                         SEQUENCE LISTING

<110>  Ramot at Tel-Aviv University Ltd.
       ELKABETZ, Yechiel
       EDRI, Reuven
       YAFFE, Yakey
       MEISSNER, Alexander
       ZILLER, Michael J.
 
<120>  POPULATIONS OF NEURAL PROGENITOR CELLS AND METHODS OF PRODUCING 
       AND USING SAME

<130>  64732

<150>  US 62/096,184
<151>  2014-12-23

<160>  4907  

<170>  PatentIn version 3.5

<210>  1
<211>  19
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  1
tggactcaac agccacgac                                                    19


<210>  2
<211>  19
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  2
cttgaactgc ttggcgaac                                                    19


<210>  3
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  3
tgtatggcaa cgtgttctcg                                                   20


<210>  4
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  4
cctcctccaa ccacttgttc                                                   20


<210>  5
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  5
tccagagcaa tctcatcgtg                                                   20


<210>  6
<211>  19
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  6
gcatgtgcgt cttcatgtg                                                    19


<210>  7
<211>  22
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  7
caacaaggaa tttgctgaag tg                                                22


<210>  8
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  8
ctatggtttc ggcttggttc                                                   20


<210>  9
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  9
gagctgagca tcctgaaagc                                                   20


<210>  10
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  10
aggcctcctt tgcaataagc                                                   20


<210>  11
<211>  21
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  11
gatagtcgcc caaagttccg t                                                 21


<210>  12
<211>  21
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  12
ctgaatgaca aggtagcgct g                                                 21


<210>  13
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  13
agagatccgc acgcagtatg                                                   20


<210>  14
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  14
tctgcaaact tggagcggta                                                   20


<210>  15
<211>  19
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  15
accagcccaa ctccaagct                                                    19


<210>  16
<211>  21
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  16
ggctttgctg tgcttcaggt a                                                 21


<210>  17
<211>  21
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  17
tgacactggc aaaacaatgc a                                                 21


<210>  18
<211>  21
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  18
ggtccttttc accagcaagc t                                                 21


<210>  19
<211>  21
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  19
cctttgtctg tgatcagtgc g                                                 21


<210>  20
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  20
cagtgccagt atgggtctgc                                                   20


<210>  21
<211>  19
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  21
aatgccgtca ccttctgtg                                                    19


<210>  22
<211>  21
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  22
ggaggacaga agctgttgtt g                                                 21


<210>  23
<211>  22
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  23
ggaaatcaaa gagcaggagg tt                                                22


<210>  24
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  24
tcctggaagt cacattcgcc                                                   20


<210>  25
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  25
tagccaaaga atgccctctc                                                   20


<210>  26
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  26
aaactcctgg cacttggttg                                                   20


<210>  27
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  27
gtcaccgcct accagaacac                                                   20


<210>  28
<211>  19
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  28
acagccggtg tagatcgtg                                                    19


<210>  29
<211>  21
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  29
agccgacaat aacatgcagg g                                                 21


<210>  30
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  30
tcctgtctca tccagtggga                                                   20


<210>  31
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  31
cctcggatga ggaaattgag                                                   20


<210>  32
<211>  20
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  32
tctgcttaca cagcccgaac                                                   20


<210>  33
<211>  20
<212>  RNA
<213>  Artificial sequence

<220>
<223>  Single strand RNA oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  5’ phosphate

<220>
<221>  misc_feature
<222>  (20)..(20)
<223>  3’ dideoxycytosine

<400>  33
agaucggaag agcgucgugc                                                   20


<210>  34
<211>  17
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  34
acacgacgct cttccga                                                      17


<210>  35
<211>  23
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  5’ phosphate

<220>
<221>  misc_feature
<222>  (23)..(23)
<223>  3’ dideoxycytosine

<400>  35
agatcggaag agcacacgtc tgc                                               23


<210>  36
<211>  124
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide


<220>
<221>  misc_feature
<222>  (83)..(90)
<223>  n is a, c, g, or t

<400>  36
aatgatacgg cgaccaccga gatctacact ctttccctac acgacgctct tccgatctca       60

agcagaagac ggcatacgag atnnnnnnnn gtgactggag ttcagacgtg tgctcttccg      120

atct                                                                   124


<210>  37
<211>  28
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  37
ctttagtttg tatgtctgtt gctattat                                          28


<210>  38
<211>  27
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  38
aatggactat catatgctta ccgtaac                                           27


<210>  39
<211>  25
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  39
ggctttatat atcttgtgga aagga                                             25


<210>  40
<211>  23
<212>  DNA
<213>  Artificial sequence

<220>
<223>  Single strand DNA oligonucleotide

<400>  40
ggatgaatac tgccatttgt ctc                                               23


<210>  41
<211>  1319
<212>  DNA
<213>  homo sapiens

<400>  41
cgcgcttggc cttgcccgcg cccgctcgcc tcgtctcgcc cggcctcccc gcgtcgcctc       60

gtcgcctgtt ccgcgccagg catggccccc agcactgtgg ccgtggagct gctcagcccc      120

aaagagaaaa accgactgcg gaagccggtg gtggagaaga tgcgccgcga ccgcatcaac      180

agcagcatcg agcagctgaa gctgctgctg gagcaggagt tcgcgcggca ccagcccaac      240

tccaagctgg agaaggccga catcctggag atggctgtca gctacctgaa gcacagcaaa      300

gccttcgtcg ccgccgccgg ccccaagagc ctgcaccagg actacagcga aggctactcg      360

tggtgcctgc aggaggccgt gcagttcctg acgctccacg ccgccagcga cacgcagatg      420

aagctgctgt accacttcca gcggcccccg gccgcgcccg ccgcgcccgc caaggagccc      480

aaggcgccgg gcgccgcgcc cccgcccgcg ctctccgcca aggccaccgc cgccgccgcc      540

gccgcgcacc agcccgcctg cggcctctgg cggccctggt gacccggcgg gacctgcggg      600

cgcgcggccc gacgaccaga gggcgagcct gctcctctcg cctgtaggga agcgccttcc      660

cgccgtcgtc cgccccgggc ttggacgcgc ccttctccgg aaggctctgg ccccaagctg      720

gccggcccgc aggagcccca ttctcagaga atgtgtgtgc agagtccctg ccgttttagg      780

acaatcaggg cccatcttct gccaagtgtc tgaccccatg gggttgttct gtgtttgcat      840

ttaagcaagt gacttctggg aagtccccgg ccgcccgggg ttctatgata tttgtagtgc      900

cggggctcgc acactgctgc ccccagcctg tagaggactt tcttcagggc ccgtagctgc      960

tgggcgtacc cctggcaggc gggctgtgcc gcgggcacat ttgccttttg tgaaggccga     1020

actcgagctg tatcctcata ggaaacagtg atcaccccgg acgggcgtcc aggaccctga     1080

gggccatggc caaaaggctc ctgagtgtgc ctggtggtct ggctggggct cacggtgggc     1140

tgtctgggga gggtgggtgc ctccactatg atccttaaag gattcctctg tgtgggtgga     1200

tgcgtgtggg cacgactttg tactcagaaa ttgaactctc agtcacgtgg aagccacggg     1260

actgctccga agccgccata ataaaatctg attgttcagc ccccaaaaaa aaaaaaaaa      1319


<210>  42
<211>  166
<212>  PRT
<213>  homo sapiens

<400>  42

Met Ala Pro Ser Thr Val Ala Val Glu Leu Leu Ser Pro Lys Glu Lys 
1               5                   10                  15      


Asn Arg Leu Arg Lys Pro Val Val Glu Lys Met Arg Arg Asp Arg Ile 
            20                  25                  30          


Asn Ser Ser Ile Glu Gln Leu Lys Leu Leu Leu Glu Gln Glu Phe Ala 
        35                  40                  45              


Arg His Gln Pro Asn Ser Lys Leu Glu Lys Ala Asp Ile Leu Glu Met 
    50                  55                  60                  


Ala Val Ser Tyr Leu Lys His Ser Lys Ala Phe Val Ala Ala Ala Gly 
65                  70                  75                  80  


Pro Lys Ser Leu His Gln Asp Tyr Ser Glu Gly Tyr Ser Trp Cys Leu 
                85                  90                  95      


Gln Glu Ala Val Gln Phe Leu Thr Leu His Ala Ala Ser Asp Thr Gln 
            100                 105                 110         


Met Lys Leu Leu Tyr His Phe Gln Arg Pro Pro Ala Ala Pro Ala Ala 
        115                 120                 125             


Pro Ala Lys Glu Pro Lys Ala Pro Gly Ala Ala Pro Pro Pro Ala Leu 
    130                 135                 140                 


Ser Ala Lys Ala Thr Ala Ala Ala Ala Ala Ala His Gln Pro Ala Cys 
145                 150                 155                 160 


Gly Leu Trp Arg Pro Trp 
                165     


<210>  43
<211>  720
<212>  DNA
<213>  Mycobacterium tuberculosis

<400>  43
atggtgagca agggcgagga gctgttcacc ggggtggtgc ccatcctggt cgagctggac       60

ggcgacgtaa acggccacaa gttcagcgtg tccggcgagg gcgagggcga tgccacctac      120

ggcaagctga ccctgaagtt catctgcacc accggcaagc tgcccgtgcc ctggcccacc      180

ctcgtgacca ccctgaccta cggcgtgcag tgcttcagcc gctaccccga ccacatgaag      240

cagcacgact tcttcaagtc cgccatgccc gaaggctacg tccaggagcg caccatcttc      300

ttcaaggacg acggcaacta caagacccgc gccgaggtga agttcgaggg cgacaccctg      360

gtgaaccgca tcgagctgaa gggcatcgac ttcaaggagg acggcaacat cctggggcac      420

aagctggagt acaactacaa cagccacaac gtctatatca tggccgacaa gcagaagaac      480

ggcatcaagg tgaacttcaa gatccgccac aacatcgagg acggcagcgt gcagctcgcc      540

gaccactacc agcagaacac ccccatcggc gacggccccg tgctgctgcc cgacaaccac      600

tacctgagca cccagtccgc cctgagcaaa gaccccaacg agaagcgcga tcacatggtc      660

ctgctggagt tcgtgaccgc cgccgggatc actctcggca tggacgagct gtacaagtaa      720


<210>  44
<211>  239
<212>  PRT
<213>  Mycobacterium tuberculosis

<400>  44

Met Val Ser Lys Gly Glu Glu Leu Phe Thr Gly Val Val Pro Ile Leu 
1               5                   10                  15      


Val Glu Leu Asp Gly Asp Val Asn Gly His Lys Phe Ser Val Ser Gly 
            20                  25                  30          


Glu Gly Glu Gly Asp Ala Thr Tyr Gly Lys Leu Thr Leu Lys Phe Ile 
        35                  40                  45              


Cys Thr Thr Gly Lys Leu Pro Val Pro Trp Pro Thr Leu Val Thr Thr 
    50                  55                  60                  


Leu Thr Tyr Gly Val Gln Cys Phe Ser Arg Tyr Pro Asp His Met Lys 
65                  70                  75                  80  


Gln His Asp Phe Phe Lys Ser Ala Met Pro Glu Gly Tyr Val Gln Glu 
                85                  90                  95      


Arg Thr Ile Phe Phe Lys Asp Asp Gly Asn Tyr Lys Thr Arg Ala Glu 
            100                 105                 110         


Val Lys Phe Glu Gly Asp Thr Leu Val Asn Arg Ile Glu Leu Lys Gly 
        115                 120                 125             


Ile Asp Phe Lys Glu Asp Gly Asn Ile Leu Gly His Lys Leu Glu Tyr 
    130                 135                 140                 


Asn Tyr Asn Ser His Asn Val Tyr Ile Met Ala Asp Lys Gln Lys Asn 
145                 150                 155                 160 


Gly Ile Lys Val Asn Phe Lys Ile Arg His Asn Ile Glu Asp Gly Ser 
                165                 170                 175     


Val Gln Leu Ala Asp His Tyr Gln Gln Asn Thr Pro Ile Gly Asp Gly 
            180                 185                 190         


Pro Val Leu Leu Pro Asp Asn His Tyr Leu Ser Thr Gln Ser Ala Leu 
        195                 200                 205             


Ser Lys Asp Pro Asn Glu Lys Arg Asp His Met Val Leu Leu Glu Phe 
    210                 215                 220                 


Val Thr Ala Ala Gly Ile Thr Leu Gly Met Asp Glu Leu Tyr Lys 
225                 230                 235                 


<210>  45
<211>  232
<212>  PRT
<213>  homo sapiens

<400>  45

Met Glu Arg Cys Pro Ser Leu Gly Val Thr Leu Tyr Ala Leu Val Val 
1               5                   10                  15      


Val Leu Gly Leu Arg Ala Thr Pro Ala Gly Gly Gln His Tyr Leu His 
            20                  25                  30          


Ile Arg Pro Ala Pro Ser Asp Asn Leu Pro Leu Val Asp Leu Ile Glu 
        35                  40                  45              


His Pro Asp Pro Ile Phe Asp Pro Lys Glu Lys Asp Leu Asn Glu Thr 
    50                  55                  60                  


Leu Leu Arg Ser Leu Leu Gly Gly His Tyr Asp Pro Gly Phe Met Ala 
65                  70                  75                  80  


Thr Ser Pro Pro Glu Asp Arg Pro Gly Gly Gly Gly Gly Ala Ala Gly 
                85                  90                  95      


Gly Ala Glu Asp Leu Ala Glu Leu Asp Gln Leu Leu Arg Gln Arg Pro 
            100                 105                 110         


Ser Gly Ala Met Pro Ser Glu Ile Lys Gly Leu Glu Phe Ser Glu Gly 
        115                 120                 125             


Leu Ala Gln Gly Lys Lys Gln Arg Leu Ser Lys Lys Leu Arg Arg Lys 
    130                 135                 140                 


Leu Gln Met Trp Leu Trp Ser Gln Thr Phe Cys Pro Val Leu Tyr Ala 
145                 150                 155                 160 


Trp Asn Asp Leu Gly Ser Arg Phe Trp Pro Arg Tyr Val Lys Val Gly 
                165                 170                 175     


Ser Cys Phe Ser Lys Arg Ser Cys Ser Val Pro Glu Gly Met Val Cys 
            180                 185                 190         


Lys Pro Ser Lys Ser Val His Leu Thr Val Leu Arg Trp Arg Cys Gln 
        195                 200                 205             


Arg Arg Gly Gly Gln Arg Cys Gly Trp Ile Pro Ile Gln Tyr Pro Ile 
    210                 215                 220                 


Ile Ser Glu Cys Lys Cys Ser Cys 
225                 230         


<210>  46
<211>  204
<212>  PRT
<213>  homo sapiens

<400>  46

Met Gly Ser Pro Arg Ser Ala Leu Ser Cys Leu Leu Leu His Leu Leu 
1               5                   10                  15      


Val Leu Cys Leu Gln Ala Gln His Val Arg Glu Gln Ser Leu Val Thr 
            20                  25                  30          


Asp Gln Leu Ser Arg Arg Leu Ile Arg Thr Tyr Gln Leu Tyr Ser Arg 
        35                  40                  45              


Thr Ser Gly Lys His Val Gln Val Leu Ala Asn Lys Arg Ile Asn Ala 
    50                  55                  60                  


Met Ala Glu Asp Gly Asp Pro Phe Ala Lys Leu Ile Val Glu Thr Asp 
65                  70                  75                  80  


Thr Phe Gly Ser Arg Val Arg Val Arg Gly Ala Glu Thr Gly Leu Tyr 
                85                  90                  95      


Ile Cys Met Asn Lys Lys Gly Lys Leu Ile Ala Lys Ser Asn Gly Lys 
            100                 105                 110         


Gly Lys Asp Cys Val Phe Thr Glu Ile Val Leu Glu Asn Asn Tyr Thr 
        115                 120                 125             


Ala Leu Gln Asn Ala Lys Tyr Glu Gly Trp Tyr Met Ala Phe Thr Arg 
    130                 135                 140                 


Lys Gly Arg Pro Arg Lys Gly Ser Lys Thr Arg Gln His Gln Arg Glu 
145                 150                 155                 160 


Val His Phe Met Lys Arg Leu Pro Arg Gly His His Thr Thr Glu Gln 
                165                 170                 175     


Ser Leu Arg Phe Glu Phe Leu Asn Tyr Pro Pro Phe Thr Arg Ser Leu 
            180                 185                 190         


Arg Gly Ser Gln Arg Thr Trp Ala Pro Glu Pro Arg 
        195                 200                 


<210>  47
<211>  233
<212>  PRT
<213>  homo sapiens

<400>  47

Met Gly Ser Pro Arg Ser Ala Leu Ser Cys Leu Leu Leu His Leu Leu 
1               5                   10                  15      


Val Leu Cys Leu Gln Ala Gln Glu Gly Pro Gly Arg Gly Pro Ala Leu 
            20                  25                  30          


Gly Arg Glu Leu Ala Ser Leu Phe Arg Ala Gly Arg Glu Pro Gln Gly 
        35                  40                  45              


Val Ser Gln Gln His Val Arg Glu Gln Ser Leu Val Thr Asp Gln Leu 
    50                  55                  60                  


Ser Arg Arg Leu Ile Arg Thr Tyr Gln Leu Tyr Ser Arg Thr Ser Gly 
65                  70                  75                  80  


Lys His Val Gln Val Leu Ala Asn Lys Arg Ile Asn Ala Met Ala Glu 
                85                  90                  95      


Asp Gly Asp Pro Phe Ala Lys Leu Ile Val Glu Thr Asp Thr Phe Gly 
            100                 105                 110         


Ser Arg Val Arg Val Arg Gly Ala Glu Thr Gly Leu Tyr Ile Cys Met 
        115                 120                 125             


Asn Lys Lys Gly Lys Leu Ile Ala Lys Ser Asn Gly Lys Gly Lys Asp 
    130                 135                 140                 


Cys Val Phe Thr Glu Ile Val Leu Glu Asn Asn Tyr Thr Ala Leu Gln 
145                 150                 155                 160 


Asn Ala Lys Tyr Glu Gly Trp Tyr Met Ala Phe Thr Arg Lys Gly Arg 
                165                 170                 175     


Pro Arg Lys Gly Ser Lys Thr Arg Gln His Gln Arg Glu Val His Phe 
            180                 185                 190         


Met Lys Arg Leu Pro Arg Gly His His Thr Thr Glu Gln Ser Leu Arg 
        195                 200                 205             


Phe Glu Phe Leu Asn Tyr Pro Pro Phe Thr Arg Ser Leu Arg Gly Ser 
    210                 215                 220                 


Gln Arg Thr Trp Ala Pro Glu Pro Arg 
225                 230             


<210>  48
<211>  244
<212>  PRT
<213>  homo sapiens

<400>  48

Met Gly Ser Pro Arg Ser Ala Leu Ser Cys Leu Leu Leu His Leu Leu 
1               5                   10                  15      


Val Leu Cys Leu Gln Ala Gln Glu Gly Pro Gly Arg Gly Pro Ala Leu 
            20                  25                  30          


Gly Arg Glu Leu Ala Ser Leu Phe Arg Ala Gly Arg Glu Pro Gln Gly 
        35                  40                  45              


Val Ser Gln Gln Val Thr Val Gln Ser Ser Pro Asn Phe Thr Gln His 
    50                  55                  60                  


Val Arg Glu Gln Ser Leu Val Thr Asp Gln Leu Ser Arg Arg Leu Ile 
65                  70                  75                  80  


Arg Thr Tyr Gln Leu Tyr Ser Arg Thr Ser Gly Lys His Val Gln Val 
                85                  90                  95      


Leu Ala Asn Lys Arg Ile Asn Ala Met Ala Glu Asp Gly Asp Pro Phe 
            100                 105                 110         


Ala Lys Leu Ile Val Glu Thr Asp Thr Phe Gly Ser Arg Val Arg Val 
        115                 120                 125             


Arg Gly Ala Glu Thr Gly Leu Tyr Ile Cys Met Asn Lys Lys Gly Lys 
    130                 135                 140                 


Leu Ile Ala Lys Ser Asn Gly Lys Gly Lys Asp Cys Val Phe Thr Glu 
145                 150                 155                 160 


Ile Val Leu Glu Asn Asn Tyr Thr Ala Leu Gln Asn Ala Lys Tyr Glu 
                165                 170                 175     


Gly Trp Tyr Met Ala Phe Thr Arg Lys Gly Arg Pro Arg Lys Gly Ser 
            180                 185                 190         


Lys Thr Arg Gln His Gln Arg Glu Val His Phe Met Lys Arg Leu Pro 
        195                 200                 205             


Arg Gly His His Thr Thr Glu Gln Ser Leu Arg Phe Glu Phe Leu Asn 
    210                 215                 220                 


Tyr Pro Pro Phe Thr Arg Ser Leu Arg Gly Ser Gln Arg Thr Trp Ala 
225                 230                 235                 240 


Pro Glu Pro Arg 
                


<210>  49
<211>  215
<212>  PRT
<213>  homo sapiens

<400>  49

Met Gly Ser Pro Arg Ser Ala Leu Ser Cys Leu Leu Leu His Leu Leu 
1               5                   10                  15      


Val Leu Cys Leu Gln Ala Gln Val Thr Val Gln Ser Ser Pro Asn Phe 
            20                  25                  30          


Thr Gln His Val Arg Glu Gln Ser Leu Val Thr Asp Gln Leu Ser Arg 
        35                  40                  45              


Arg Leu Ile Arg Thr Tyr Gln Leu Tyr Ser Arg Thr Ser Gly Lys His 
    50                  55                  60                  


Val Gln Val Leu Ala Asn Lys Arg Ile Asn Ala Met Ala Glu Asp Gly 
65                  70                  75                  80  


Asp Pro Phe Ala Lys Leu Ile Val Glu Thr Asp Thr Phe Gly Ser Arg 
                85                  90                  95      


Val Arg Val Arg Gly Ala Glu Thr Gly Leu Tyr Ile Cys Met Asn Lys 
            100                 105                 110         


Lys Gly Lys Leu Ile Ala Lys Ser Asn Gly Lys Gly Lys Asp Cys Val 
        115                 120                 125             


Phe Thr Glu Ile Val Leu Glu Asn Asn Tyr Thr Ala Leu Gln Asn Ala 
    130                 135                 140                 


Lys Tyr Glu Gly Trp Tyr Met Ala Phe Thr Arg Lys Gly Arg Pro Arg 
145                 150                 155                 160 


Lys Gly Ser Lys Thr Arg Gln His Gln Arg Glu Val His Phe Met Lys 
                165                 170                 175     


Arg Leu Pro Arg Gly His His Thr Thr Glu Gln Ser Leu Arg Phe Glu 
            180                 185                 190         


Phe Leu Asn Tyr Pro Pro Phe Thr Arg Ser Leu Arg Gly Ser Gln Arg 
        195                 200                 205             


Thr Trp Ala Pro Glu Pro Arg 
    210                 215 


<210>  50
<211>  140
<212>  PRT
<213>  homo sapiens

<400>  50

Met Ala Glu Asp Gly Asp Pro Phe Ala Lys Leu Ile Val Glu Thr Asp 
1               5                   10                  15      


Thr Phe Gly Ser Arg Val Arg Val Arg Gly Ala Glu Thr Gly Leu Tyr 
            20                  25                  30          


Ile Cys Met Asn Lys Lys Gly Lys Leu Ile Ala Lys Ser Asn Gly Lys 
        35                  40                  45              


Gly Lys Asp Cys Val Phe Thr Glu Ile Val Leu Glu Asn Asn Tyr Thr 
    50                  55                  60                  


Ala Leu Gln Asn Ala Lys Tyr Glu Gly Trp Tyr Met Ala Phe Thr Arg 
65                  70                  75                  80  


Lys Gly Arg Pro Arg Lys Gly Ser Lys Thr Arg Gln His Gln Arg Glu 
                85                  90                  95      


Val His Phe Met Lys Arg Leu Pro Arg Gly His His Thr Thr Glu Gln 
            100                 105                 110         


Ser Leu Arg Phe Glu Phe Leu Asn Tyr Pro Pro Phe Thr Arg Ser Leu 
        115                 120                 125             


Arg Gly Ser Gln Arg Thr Trp Ala Pro Glu Pro Arg 
    130                 135                 140 


<210>  51
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  51

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  52
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  52

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  53
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  53

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  54
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  54

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  55
<211>  276
<212>  PRT
<213>  homo sapiens

<400>  55

Met Leu Cys Ala Ile Ser Leu Cys Ala Arg Val Arg Lys Leu Arg Ser 
1               5                   10                  15      


Ala Gly Arg Cys Gly Lys Phe His Gln Val Arg Arg Val Met Thr Ile 
            20                  25                  30          


Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met Lys Ala Ala 
        35                  40                  45              


Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu Ala Tyr Pro 
    50                  55                  60                  


Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly Pro Lys Ala 
65                  70                  75                  80  


Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu His Val Ile 
                85                  90                  95      


Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn Glu Glu Asn 
            100                 105                 110         


Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu Ser Ser Gln 
        115                 120                 125             


Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu Tyr Lys Asn 
    130                 135                 140                 


Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg His Ser Asp 
145                 150                 155                 160 


Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile Ser Glu Trp 
                165                 170                 175     


Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser Gly Gly Thr 
            180                 185                 190         


Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln Leu Lys Gln 
        195                 200                 205             


Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr Lys Glu Gly 
    210                 215                 220                 


Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys Arg Thr Thr 
225                 230                 235                 240 


Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys Arg Ile Gly 
                245                 250                 255     


Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr Leu Thr Ile 
            260                 265                 270         


Lys Arg Gly Arg 
        275     


<210>  56
<211>  329
<212>  PRT
<213>  homo sapiens

<400>  56

Met Cys Gly Ala Thr Ser Phe Leu His Glu Cys Thr Arg Leu Ile Leu 
1               5                   10                  15      


Val Thr Thr Gln Asn Ala Glu Phe Leu Gln Lys Gly Leu Gln Val His 
            20                  25                  30          


Thr Cys Phe Gly Val Tyr Pro His Ala Ser Val Trp His Asp Cys Ala 
        35                  40                  45              


Ser Gln Lys Lys Gly Cys Ala Val Tyr Leu His Val Ser Val Glu Phe 
    50                  55                  60                  


Asn Lys Leu Ile Pro Glu Asn Gly Phe Ile Lys Phe His Gln Val Arg 
65                  70                  75                  80  


Arg Val Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly 
                85                  90                  95      


Cys Met Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly 
            100                 105                 110         


Gly Leu Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val 
        115                 120                 125             


Asn Gly Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr 
    130                 135                 140                 


Phe Glu His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg 
145                 150                 155                 160 


Pro Asn Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val 
                165                 170                 175     


Met Leu Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu 
            180                 185                 190         


Glu Glu Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val 
        195                 200                 205             


Arg Arg His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp 
    210                 215                 220                 


Ser Ile Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp 
225                 230                 235                 240 


Met Ser Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys 
                245                 250                 255     


Gly Gln Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly 
            260                 265                 270         


Tyr Thr Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser 
        275                 280                 285             


Gln Cys Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser 
    290                 295                 300                 


Lys Lys Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val 
305                 310                 315                 320 


Cys Thr Leu Thr Ile Lys Arg Gly Arg 
                325                 


<210>  57
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  57

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  58
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  58

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  59
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  59

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  60
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  60

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  61
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  61

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  62
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  62

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  63
<211>  255
<212>  PRT
<213>  homo sapiens

<400>  63

Met Phe His Gln Val Arg Arg Val Met Thr Ile Leu Phe Leu Thr Met 
1               5                   10                  15      


Val Ile Ser Tyr Phe Gly Cys Met Lys Ala Ala Pro Met Lys Glu Ala 
            20                  25                  30          


Asn Ile Arg Gly Gln Gly Gly Leu Ala Tyr Pro Gly Val Arg Thr His 
        35                  40                  45              


Gly Thr Leu Glu Ser Val Asn Gly Pro Lys Ala Gly Ser Arg Gly Leu 
    50                  55                  60                  


Thr Ser Leu Ala Asp Thr Phe Glu His Val Ile Glu Glu Leu Leu Asp 
65                  70                  75                  80  


Glu Asp Gln Lys Val Arg Pro Asn Glu Glu Asn Asn Lys Asp Ala Asp 
                85                  90                  95      


Leu Tyr Thr Ser Arg Val Met Leu Ser Ser Gln Val Pro Leu Glu Pro 
            100                 105                 110         


Pro Leu Leu Phe Leu Leu Glu Glu Tyr Lys Asn Tyr Leu Asp Ala Ala 
        115                 120                 125             


Asn Met Ser Met Arg Val Arg Arg His Ser Asp Pro Ala Arg Arg Gly 
    130                 135                 140                 


Glu Leu Ser Val Cys Asp Ser Ile Ser Glu Trp Val Thr Ala Ala Asp 
145                 150                 155                 160 


Lys Lys Thr Ala Val Asp Met Ser Gly Gly Thr Val Thr Val Leu Glu 
                165                 170                 175     


Lys Val Pro Val Ser Lys Gly Gln Leu Lys Gln Tyr Phe Tyr Glu Thr 
            180                 185                 190         


Lys Cys Asn Pro Met Gly Tyr Thr Lys Glu Gly Cys Arg Gly Ile Asp 
        195                 200                 205             


Lys Arg His Trp Asn Ser Gln Cys Arg Thr Thr Gln Ser Tyr Val Arg 
    210                 215                 220                 


Ala Leu Thr Met Asp Ser Lys Lys Arg Ile Gly Trp Arg Phe Ile Arg 
225                 230                 235                 240 


Ile Asp Thr Ser Cys Val Cys Thr Leu Thr Ile Lys Arg Gly Arg 
                245                 250                 255 


<210>  64
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  64

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  65
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  65

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  66
<211>  262
<212>  PRT
<213>  homo sapiens

<400>  66

Met Gln Ser Arg Glu Glu Glu Trp Phe His Gln Val Arg Arg Val Met 
1               5                   10                  15      


Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met Lys 
            20                  25                  30          


Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu Ala 
        35                  40                  45              


Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly Pro 
    50                  55                  60                  


Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu His 
65                  70                  75                  80  


Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn Glu 
                85                  90                  95      


Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu Ser 
            100                 105                 110         


Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu Tyr 
        115                 120                 125             


Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg His 
    130                 135                 140                 


Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile Ser 
145                 150                 155                 160 


Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser Gly 
                165                 170                 175     


Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln Leu 
            180                 185                 190         


Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr Lys 
        195                 200                 205             


Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys Arg 
    210                 215                 220                 


Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys Arg 
225                 230                 235                 240 


Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr Leu 
                245                 250                 255     


Thr Ile Lys Arg Gly Arg 
            260         


<210>  67
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  67

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15      


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30          


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45              


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60                  


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80  


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95      


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110         


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125             


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140                 


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160 


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175     


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190         


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205             


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220                 


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240 


Leu Thr Ile Lys Arg Gly Arg 
                245         


<210>  68
<211>  462
<212>  PRT
<213>  homo sapiens

<400>  68

Met Leu Leu Leu Ala Arg Cys Leu Leu Leu Val Leu Val Ser Ser Leu 
1               5                   10                  15      


Leu Val Cys Ser Gly Leu Ala Cys Gly Pro Gly Arg Gly Phe Gly Lys 
            20                  25                  30          


Arg Arg His Pro Lys Lys Leu Thr Pro Leu Ala Tyr Lys Gln Phe Ile 
        35                  40                  45              


Pro Asn Val Ala Glu Lys Thr Leu Gly Ala Ser Gly Arg Tyr Glu Gly 
    50                  55                  60                  


Lys Ile Ser Arg Asn Ser Glu Arg Phe Lys Glu Leu Thr Pro Asn Tyr 
65                  70                  75                  80  


Asn Pro Asp Ile Ile Phe Lys Asp Glu Glu Asn Thr Gly Ala Asp Arg 
                85                  90                  95      


Leu Met Thr Gln Arg Cys Lys Asp Lys Leu Asn Ala Leu Ala Ile Ser 
            100                 105                 110         


Val Met Asn Gln Trp Pro Gly Val Lys Leu Arg Val Thr Glu Gly Trp 
        115                 120                 125             


Asp Glu Asp Gly His His Ser Glu Glu Ser Leu His Tyr Glu Gly Arg 
    130                 135                 140                 


Ala Val Asp Ile Thr Thr Ser Asp Arg Asp Arg Ser Lys Tyr Gly Met 
145                 150                 155                 160 


Leu Ala Arg Leu Ala Val Glu Ala Gly Phe Asp Trp Val Tyr Tyr Glu 
                165                 170                 175     


Ser Lys Ala His Ile His Cys Ser Val Lys Ala Glu Asn Ser Val Ala 
            180                 185                 190         


Ala Lys Ser Gly Gly Cys Phe Pro Gly Ser Ala Thr Val His Leu Glu 
        195                 200                 205             


Gln Gly Gly Thr Lys Leu Val Lys Asp Leu Ser Pro Gly Asp Arg Val 
    210                 215                 220                 


Leu Ala Ala Asp Asp Gln Gly Arg Leu Leu Tyr Ser Asp Phe Leu Thr 
225                 230                 235                 240 


Phe Leu Asp Arg Asp Asp Gly Ala Lys Lys Val Phe Tyr Val Ile Glu 
                245                 250                 255     


Thr Arg Glu Pro Arg Glu Arg Leu Leu Leu Thr Ala Ala His Leu Leu 
            260                 265                 270         


Phe Val Ala Pro His Asn Asp Ser Ala Thr Gly Glu Pro Glu Ala Ser 
        275                 280                 285             


Ser Gly Ser Gly Pro Pro Ser Gly Gly Ala Leu Gly Pro Arg Ala Leu 
    290                 295                 300                 


Phe Ala Ser Arg Val Arg Pro Gly Gln Arg Val Tyr Val Val Ala Glu 
305                 310                 315                 320 


Arg Asp Gly Asp Arg Arg Leu Leu Pro Ala Ala Val His Ser Val Thr 
                325                 330                 335     


Leu Ser Glu Glu Ala Ala Gly Ala Tyr Ala Pro Leu Thr Ala Gln Gly 
            340                 345                 350         


Thr Ile Leu Ile Asn Arg Val Leu Ala Ser Cys Tyr Ala Val Ile Glu 
        355                 360                 365             


Glu His Ser Trp Ala His Arg Ala Phe Ala Pro Phe Arg Leu Ala His 
    370                 375                 380                 


Ala Leu Leu Ala Ala Leu Ala Pro Ala Arg Thr Asp Arg Gly Gly Asp 
385                 390                 395                 400 


Ser Gly Gly Gly Asp Arg Gly Gly Gly Gly Gly Arg Val Ala Leu Thr 
                405                 410                 415     


Ala Pro Gly Ala Ala Asp Ala Pro Gly Ala Gly Ala Thr Ala Gly Ile 
            420                 425                 430         


His Trp Tyr Ser Gln Leu Leu Tyr Gln Ile Gly Thr Trp Leu Leu Asp 
        435                 440                 445             


Ser Glu Ala Leu His Pro Leu Gly Met Ala Val Lys Ser Ser 
    450                 455                 460         


<210>  69
<211>  179
<212>  PRT
<213>  homo sapiens

<400>  69

Met Leu Ser Leu Phe Pro Ser Pro Gly Pro Gly Ser Ser Arg Cys Lys 
1               5                   10                  15      


Asp Lys Leu Asn Ala Leu Ala Ile Ser Val Met Asn Gln Trp Pro Gly 
            20                  25                  30          


Val Lys Leu Arg Val Thr Glu Gly Trp Asp Glu Asp Gly His His Ser 
        35                  40                  45              


Glu Glu Ser Leu His Tyr Glu Gly Arg Ala Val Asp Ile Thr Thr Ser 
    50                  55                  60                  


Asp Arg Asp Arg Ser Lys Tyr Gly Met Leu Ala Arg Leu Ala Val Glu 
65                  70                  75                  80  


Ala Gly Phe Asp Trp Val Tyr Tyr Glu Ser Lys Ala His Ile His Cys 
                85                  90                  95      


Ser Val Lys Ala Gly Lys Glu Arg Lys Pro Leu Leu Arg Asp Thr Arg 
            100                 105                 110         


Tyr Arg Ala Ser Arg Gly Cys Ser Pro Ala Pro Pro Gly Arg Gly Ala 
        115                 120                 125             


Asp Phe Ser Phe Arg Val Asp Gly Ala Lys Ser Leu Cys Lys Met Tyr 
    130                 135                 140                 


Ala Trp Trp Leu Leu Pro Ala Ser Leu Met Thr Lys Cys Ile Ser Ile 
145                 150                 155                 160 


Pro Val Lys Thr Cys Ile Thr Met Tyr Leu Lys Leu Leu Ser Leu Cys 
                165                 170                 175     


Ser Ile Val 
            


<210>  70
<211>  953
<212>  DNA
<213>  homo sapiens

<400>  70
ggactagcag ttctctgcgg agggccggtt gatacagttc cggtgggaga acgcggctgc       60

gaggttttcg gctttggctc ctgatatgca gcgacagaat tttcggcccc caactcctcc      120

ttaccctggt ccgggtggag gaggttgggg tagcggaagc agcttccggg gaaccccggg      180

cgggggcgga ccacggccgc cctcccctcg agacgggtac gggagtccgc accacacgcc      240

gccgtacggg ccccggtcta ggccgtacgg gagcagtcac tctccgcgac acggcggcag      300

cttcccgggg ggccggttcg ggtctccgtc ccctggcggc taccctggct cctactccag      360

gtcccccgcg gggtcccagc agcaattcgg ctactcccca gggcagcagc agacccaccc      420

ccagggttct ccaaggacat ctacaccatt tggatcaggg cgtgttagag aaaaaagaat      480

gtctaatgag ttggaaaatt atttcaagcc ttcaatgctt gaagatcctt gggctggcct      540

agaaccagta tctgtagtgg atataagcca acaatacagc aatactcaaa cattcacagg      600

caaaaaagga agatactttt gttaacattt ctgaaattca actggaagct tcatgtgtca      660

ggaacatctt ggacaaaact ttaagttgtg ttgatataaa tttacccaaa gatgatgact      720

ttgattggat aattagtaag gtctttttgt tatttttcat cgtatcaggt attgttgata      780

ttagagaaaa aagtaggata acttgcaaca tttagctctg gaagtaccta ccacatttta      840

gagatttacc gtttccatat atttaacatt cctggttaca taatggacat ttgtctttta      900

atgttttttc aatgttttaa aataaaacat tttgtcttct aaaaaaaaaa aaa             953


<210>  71
<211>  16114
<212>  DNA
<213>  homo sapiens

<400>  71
atggacttag caccagacag ggctactggc cgcccgtggc tcccgttgca cactctatca       60

gtatctcagc tccttcgagt gttttggcta ctgtcattgc ttccggggca ggcctgggtc      120

cacggggccg agccgcgcca ggtgttccaa gtgctggaag agcaacctcc aggcactctg      180

gtaggcacca tccagacgcg ccccggcttc acctacaggc tcagcgaaag ccacgccctg      240

tttgccataa acagtagcac cggagccctg tacaccacct ccaccatcga ccgcgagagc      300

ctgcccagcg acgtgatcaa cctggtggtc ctttccagcg cgcccaccta ccccaccgaa      360

gtgcgagtgc tggtgcggga cctcaatgac aacgcccccg ttttcccgga cccctctatc      420

gtggtcactt tcaaggaaga cagtagcagc ggacgccaag tcatcttaga caccgccacc      480

gactcggaca tcggctcaaa cggtgtggac caccgctcct accgcatcat ccgcggcaat      540

gaggcggggc gcttccgtct ggacatcacc ctgaacccga gcggcgaggg agcgttcctg      600

catctggtgt ccaagggcgg actggaccgt gaggtcactc cgcagtacca gctcctggtt      660

gaggtggagg acaagggtga gcctaagcgg cggggctacc ttcaggtaaa cgtgactgtg      720

caagacatta atgacaaccc cccggttttt ggcagttctc actaccaggc gggggtgcct      780

gaggacgcgg ttgtgggttc cagcgtcctc caggtggcgg cggcggacgc ggacgagggc      840

accaacgcgg acatccgcta tcgcctgcag gacgagggga cccccttcca aatggaccct      900

gagacgggac ttatcacggt gcgggagccc ctggacttcg aagctcggcg ccaatactcg      960

cttacggtgc aggcgatgga cagaggcgtg ccttccctca ctgggcgcgc cgaggcgctg     1020

attcagctgc tggacgtgaa tgacaatgac ccggtagtga agttccgcta cttcccggcc     1080

acctcgcgct acgcctcggt agatgagaat gctcaagtgg gcaccgtggt ggctctgctc     1140

accgtgacgg acgcagattc tcccgcggcc aacgggaaca tctccgtgca aattctcggg     1200

ggcaatgagc agcgccactt tgaagtgcaa agcagcaaag tgccgaacct gagcctaatc     1260

aaggtggcca gcgccttgga ccgcgagcgc atcccttcct acaacctcac agtttccgtc     1320

tctgataact acggggcgcc ccctggcgca gcagtccagg cgcgctcttc tgtggcaagc     1380

ctggtgattt ttgttaatga catcaatgac catcctcctg tcttttcaca gcaagtgtac     1440

agagtgaacc tgagcgagga ggcgcctccg ggaagctatg tgagtgggat atctgccact     1500

gatggcgact ctggtctcaa tgctaatctg cgttacagca ttgtctctgg caatggactg     1560

ggatggttcc atatcagtga acatagcggc ctcgtgacca ctgggtcctc tgggggcctg     1620

gaccgtgaac ttgcttccca gattgttctg aatataagtg cccgggacca gggagttcac     1680

cccaaggtgt cctatgccca gcttgtagta actctcctag atgtgaatga tgaaaagcca     1740

gtatttagcc agccagaagg gtatgatgtg tctgtggttg agaatgcccc aacagggaca     1800

gaactgttga tgctcagggc aactgacggg gacctgggtg acaacggaac agtgcgcttc     1860

tccttacaag aggcagagac tgaccggagg tccttccgtc tggatcctgt gtctgggagg     1920

ttgagtacta tttcctcctt ggacagagaa gagcaagcct tctactccct gttggttctg     1980

gccacagatc tgggctcccc tccccagtca tcaatggctc gcataaatgt gagtcttctg     2040

gatataaatg ataacagccc tgtcttctac ccggtccaat actttgctca cattaaggag     2100

aatgagcctg gaggtagcta catcaccact gtgtctgcca ctgacccaga cttgggtacc     2160

aatggtactg tcaaatatag catatctgct ggggacaggt ctcggtttca ggtcaatgct     2220

cagagtgggg ttatttctac aagaatggcc ctagacagag aagaaaaaac agcttatcag     2280

ttgcaaatag tagctactga tggtggcaat ttacaatctc ccaaccaggc aatagtaacc     2340

atcactgtat tggacactca agacaaccca cctgtattca gtcaggttgc ctacagcttt     2400

gtggtttttg agaacgtggc gctgggatat catgtgggta gtgtgtctgc atccaccatg     2460

gatctcaatt ccaacatcag ttatctcatt actactgggg atcagaaagg tatgtttgct     2520

atcaaccagg tcactgggca gcttaccaca gcaaatgtga ttgatagaga agagcaatcc     2580

ttttatcagc tgaaggtagt ggccagtggg ggcacagtga ctggagacac tatggttaac     2640

ataacagtta aggatttgaa tgacaactct ccccatttcc ttcaggcaat agagagtgta     2700

aatgtggtgg agaattggca ggcaggtcac agcattttcc aggccaaagc tgtggaccct     2760

gatgaaggtg tcaatggcat ggtactctat agtctgaagc aaaaccccaa gaacctgttt     2820

gctatcaatg aaaagaatgg cactattagt ctgcttgggc ccctggatgt tcatgctggc     2880

tcctaccaaa tagagatctt ggcatctgac atgggtgtcc cacagctctc ctctagtgtc     2940

atcttaacag tttatgtcca tgatgtaaat gacaattcac cagtgtttga ccaactctct     3000

tatgaagtca ccctttctga gtcagaacct gtgaattctc gattctttaa agtacaagct     3060

tctgataagg attcaggagc aaatggtgaa attgcataca ccattgctga aggaaataca     3120

ggggatgctt ttggcatatt cccagatggt caattgtata taaaaagtga actggaccgt     3180

gaacttcaag acagatatgt tttaatggtt gttgcttctg acagagcagt ggaacccctt     3240

agtgctactg tgaatgttac tgtaatttta gaagatgtaa atgataacag acctcttttt     3300

aacagtacca attacacatt ttacttcgaa gaagagcaga gggctgggtc gtttgtgggc     3360

aaagtaagtg ctgtagataa agactttggg ccaaatggag aagtaaggta ttcttttgaa     3420

atggtgcagc cagattttga gttgcatgcc atcagtgggg aaattacaaa tactcatcag     3480

tttgacaggg agtctcttat gaggcggaga gggactgctg tgtttagctt tacagtcata     3540

gcaacagatc aggggatccc tcagcctctc aaggatcagg ccactgtaca tgtttacatg     3600

aaggatataa atgataatgc tcccaaattt ttaaaagact tttaccaagc tacaatatca     3660

gaatcagcag ccaatctgac acaagtgtta agagtatctg cctcagatgt tgatgaaggt     3720

aataatggac ttattcacta ttctataata aaaggaaatg aagaaagaca gtttgctata     3780

gacagtacct ctggtcaggt aacactaatt ggcaaattag actatgaagc aacacctgcc     3840

tattcccttg taattcaagc agtggattca gggacaatcc ccctcaattc aacgtgtact     3900

ttaaatattg atattttaga tgaaaatgac aatacccctt ctttccctaa atcaacactc     3960

tttgttgatg ttttggaaaa catgagaatt ggtgaactcg tgtcctctgt tactgcaact     4020

gattccgatt caggtgacaa tgctgattta tattacagta ttactgggac taacaaccac     4080

ggaactttta gcattagccc aaacactggg agtatttttc ttgccaaaaa actggacttt     4140

gaaacacagt ctttgtataa attaaatata acagcaaaag accaaggaag acctcctcgt     4200

tcatctacaa tgtcagtggt tattcacgtg agggacttta atgacaatcc tcctagcttt     4260

cctcctggag atattttcaa gtctattgtt gagaacattc ccatcggtac atctgtcatt     4320

tcagtgactg cacatgaccc tgatgcagac attaatggtc aactatccta cacaatcatt     4380

caacagatgc caagaggcaa ccactttacc atagatgaag tcaaagggac tatatatact     4440

aatgctgaaa tagatcggga atttgctaat ctctttgagt tgactgtaaa agccaatgat     4500

caagctgtgc caatagaaac tagacggtat gctttgaaga acgtgaccat tttggttaca     4560

gacctcaatg acaatgtccc aatgtttata tcacaaaacg cccttgctgc agacccatca     4620

gctgtgattg gttccgttct gacaacaatt atggctgctg acccagatga aggtgctaat     4680

ggagaaatag agtatgagat catcaatggg gacacagaca ccttcattgt tgatcgttat     4740

agtggagacc tgagagtggc ttcagcgttg gtgccttcac agttgatcta caatctcata     4800

gtttcagcaa cagaccttgg gcctgaaagg aggaaatcga ccactgaatt gaccatcatt     4860

cttcagggcc ttgatggacc tgtttttact caacccaaat atataactat tttgaaggaa     4920

ggagaaccca ttggcacaaa cgtgatatca atagaagcag ctagccccag aggatctgag     4980

gccccagtgg agtattatat tgtttcagtt cgttgtgaag aaaaaactgt tggacgcctc     5040

tttactattg gacgacatac tggtataatt cagaccgcag ccattctgga ccgggagcaa     5100

ggagcatgtc tttacctggt ggatgtttat gccatagaaa aatcaactgc ttttcccaga     5160

acacagagag cagaggtaga aataacactt caggatatca atgacaatcc accagtattt     5220

ccaacggaca tgctggatct cacggtagag gagaacattg gagatggctc taagattatg     5280

cagctgacag ccatggatgc tgatgagggt gcaaatgctc tcgtcacata cactatcatt     5340

agtggagctg atgatagttt tcgcatcgac ccagaatccg gagatctgat agcaaccagg     5400

cggttggaca gggaacgccg ctccaaatat tcactgctag ttcgtgctga tgatggtctt     5460

cagtcctcgg atatgagaat taatatcact gtcagtgatg tgaatgacca tacacccaaa     5520

ttttccagac ccgtgtactc ttttgacatt cctgaggaca caatccctgg ttctttggta     5580

gcagccattt tagccacgga tgatgactct ggtgtgaatg gagaaattac atatattgtg     5640

aatgaagatg atgaagatgg catctttttc ctgaatccta ttactggggt ctttaatttg     5700

actcgattat tagattatga agtacagcaa tattatatcc tcactgttcg agcagaagat     5760

ggtgggggac aatttactac catcagagtt tatttcaata ttctagatgt aaatgataat     5820

ccacctattt tcagcttgaa ttcatacagc acatctttaa tggagaatct acctgtggga     5880

tctactgttc ttgtgtttaa tgttactgat gcagatgatg gcatcaactc tcaattgact     5940

tatagcattg cttcaggtga tagccttggg cagtttactg ttgacaagaa tggtgtactc     6000

aaagtcctaa aagctttgga tcgggaaagt cagtccttct acaacttggt tgttcaagtg     6060

catgacctgc cacagattcc agcctccaga ttcacaagca ctgctcaagt ctccattatt     6120

ttgttggatg taaatgataa cccaccgaca tttctttccc ctaaattgac atacattcca     6180

gaaaatacac ctattgatac tgttgttttc aaagctcaag caactgaccc agatagtggc     6240

ccaaacagct atattgagta cactctgctg aaccctttgg gaaacaagtt cagtattggg     6300

accattgatg gtgaagtgag gctcactgga gaactggaca gagaagaagt ttctaattat     6360

actctaacag tggtggctac agacaaaggt caaccatctc tctcttcatc tacagaggtt     6420

gtagttatgg tacttgacat caatgataac aaccccatct ttgcacaagc tttgtataaa     6480

gtggagatta atgaaaacac acttactgga acagatataa tacaagtgtt cgcagcagat     6540

ggagatgaag gcacaaatgg acaggttcgc tatggcattg ttaatggtaa taccaatcag     6600

gaatttcgga tagactctgt cacaggtgcc atcactgtcg ctaaaccttt ggatagagaa     6660

aagaccccta cctaccattt aactgttcag gcaacagatc gaggcagcac acccagaact     6720

gatacctcca cggtcagcat tgttctactg gatattaatg actttgttcc tgtatttgag     6780

ctatctccat attctgtaaa tgtccctgag aatttaggga cactacccag aacaattctt     6840

caggtggtgg caagagatga tgatcgagga tctaacagca aactctcata tgttctgttt     6900

ggtggtaatg aagacaatgc ttttactctc tcagccagtg gagaacttgg agtaacacag     6960

agtctggatc gggaaacaaa agagcgcttt gtcttaatga ttacagctac agattcagga     7020

tcccctgcct tgactggaac tggaacaatc aacgtcatag tagatgatgt caatgacaat     7080

gtccccacat ttgccagtaa agcgtatttc acaacaattc ctgaggatgc accaactgga     7140

acagatgttt tattggtaaa tgcctcagat gctgatgctt caaagaatgc agttataagg     7200

atcatcggtg gaaactctca gttcacgatc aacccatcga caggacaaat catcaccagc     7260

gcattgttag atagggaaac aaaagataat tatactttgg tagtggtctg cagtgatgcg     7320

ggatccccag agcctctttc cagttccacc agtgtgcttg tcactgtgac tgatgtcaat     7380

gacaatccac caagatttca gcatcaccca tatgtcactc acatcccatc tcctactctt     7440

ccaggttcct ttgtctttgc ggttacagtc acagatgctg atattggacc aaattctgaa     7500

ctgcattatt ctctttcggg tagaaattct gaaaaatttc acattgaccc actgagggga     7560

gccattatgg ccgccggacc actaaacgga gcttcagaag tgacattttc tgtgcatgta     7620

aaagatggtg gctcatttcc aaagacagat tctacaacag tgactgttag attcgtgaat     7680

aaggccgatt tccctaaagt gagagccaaa gaacaaacgt tcatgtttcc tgaaaaccaa     7740

ccagtcagct ctcttgtcac caccatcaca ggatcctctt taagaggaga acctatgtca     7800

tattatatcg caagtgggaa tcttggcaat actttccaga ttgatcagtt aacagggcag     7860

gtgtctatta gtcaacctct ggattttgaa aagatacaaa aatatgttgt atggatagag     7920

gccagagacg gtggtttccc tcctttctcc tcttacgaga aacttgatat aacagtatta     7980

gatgtcaatg ataatgcccc aatttttaag gaagacccat ttatatctga aatattggaa     8040

aacctttccc ctcgaaaaat acttactgtt tcggcaatgg acaaggacag tggacccaat     8100

ggacagttag attatgaaat tgttaatggc aacatggaaa atagtttcag tatcaatcat     8160

gctactggtg aaattagaag cgttagacct ttggacaggg aaaaagtatc tcattatgtc     8220

ctaaccataa aatcatcaga caaagggtcc ccgtctcaga gtacttcagt aaaagtcatg     8280

attaacattt tagatgaaaa tgataatgcc cctaggtttt ctcagatatt tagtgcccat     8340

gttcctgaaa attccccctt aggatacaca gttacccgtg tcacaacttc tgatgaagac     8400

attgggatca atgcaattag tagatattct ataatggatg caagtcttcc atttacaatt     8460

aatcccagca caggggatat tgtcataagc agacctttaa atagggaaga tacagaccgt     8520

tacagaattc gagtttccgc acatgattct gggtggactg taagtacaga tgtcacaata     8580

tttgtgacag acatcaatga caatgctcca agatttagca gaacttccta ttatttagat     8640

tgccctgaac ttactgagat tggctccaaa gtaactcagg tatttgcaac agatcctgat     8700

gagggatcaa atggacaagt gttttatttc ataaaatccc aatcagaata tttcaggatt     8760

aatgccacca ctggagagat tttcaataaa cagatcttaa aataccaaaa tgtcactggc     8820

ttcagtaatg tgaatatcaa caggcatagt tttatagtga catcttcaga tcgaggtaaa     8880

ccttccttaa ttagtgagac aacagttacc atcaatatag tggacagtaa tgacaatgca     8940

cctcaatttc ttaaaagtaa atatttcact ccagtcacca aaaatgttaa ggttggtacg     9000

aagttaatca gagttacagc aatagatgac aaagattttg gactgaattc agaagtggag     9060

tatttcattt ctaatgataa ccatttagga aaatttaagt tggacaatga tacggggtgg     9120

atttcagtag catcctccct gatttctgac ttgaaccaaa acttttttat cacagtcact     9180

gcaaaggata agggaaaccc tccactttct tcccaagcaa ctgttcacat aactgtcact     9240

gaggaaaact accatacacc tgaattctct caaagccaca tgagtgcaac catccctgag     9300

agccatagca ttgggtccat tgtcagaact gtttctgcaa gagatagaga tgcagcgatg     9360

aatggcttga ttaagtacag catttcttca ggaaatgaag aaggcatttt tgcaatcaat     9420

tcttctacag gtatattaac actagccaaa gctcttgatt atgagctatg ccagaaacac     9480

gaaatgacga ttagtgctat agatggagga tgggttgcaa gaactggtta ctgcagtgtg     9540

accgtaaatg tgattgatgt gaatgataat tctccagtat tcctctctga tgactatttc     9600

cctactgttt tggaaaatgc cccaagtgga acaacagtta tccacctaaa tgcaacagat     9660

gctgactctg gaacaaatgc tgtgattgcg tatactgtac agtcatctga cagtgacctc     9720

tttgtcattg accctaacac aggagtcata accactcaag gcttcttgga ttttgaaacc     9780

aagcagagct accatcttac tgtgaaagcc ttcaatgtcc ccgatgagga aaggtgtagc     9840

tttgccactg ttaatataca attaaaaggg acaaatgaat atgtgccccg ttttgtttcc     9900

aaactttact attttgaaat ctcagaagca gctcctaaag gtactattgt tggagaagtg     9960

tttgctagcg accgtgattt gggcactgat ggggaggtac actatttgat ttttggtaat    10020

agtcgaaaga agggtttcca gatcaataag aagactggac agatttatgt ttctggaatt    10080

cttgatcgag aaaaagaaga aagggtgtct ttgaaggtat tggccaagaa ctttggcagc    10140

attagaggtg cagatataga tgaggtcact gtaaatgtca ccgtgcttga tgcaaatgac    10200

ccacccattt ttactctaaa catctacagt gtgcagatca gtgaaggggt cccaatagga    10260

actcatgtga cctttgtcag tgcctttgac tcagactcca tccccagctg gagcaggttt    10320

tcttacttca tcggatcagg gaatgaaaat ggtgcctttt ctattaatcc gcagacagga    10380

cagatcaccg ttactgcaga attagatcga gaaacccttc ccatctataa tctctcagtt    10440

ttggctgttg attcagggac cccctcagct acaggtagtg cctctttatt agtcaccctg    10500

gaagatataa atgataacgg gcccatgctg actgtcagtg aaggagaagt catggaaaac    10560

aaacggccag gcactttggt gatgaccctt cagtccactg accctgatct ccctccaaat    10620

caaggtccct ttacttatta cttgctgagc acaggtcctg ccaccagtta tttcagtctg    10680

agcactgctg gagttctgag cacaaccaga gagattgaca gagagcagat tgcagacttc    10740

tatctgtctg tggttaccaa ggattctggt gttcctcaaa tgtcttccac aggaactgtg    10800

catatcacag ttatagacca aaatgacaat ccttcacagt ctcggacggt ggagatattt    10860

gttaattatt atggtaactt gtttcccggt gggattttag gctctgtgaa gccacaggat    10920

ccagatgtgt tagacagctt ccactgctcc cttacttcag gagttaccag cctcttcagt    10980

attccagggg gtacttgtga tctgaattcc cagccaaggt ccacagatgg cacgtttgat    11040

ctgactgtcc ttagcaatga tggagttcac agcacagtca cgagcaacat ccgagttttc    11100

tttgctggat tttccaatgc cacagtggat aacagcatct tacttcgtct cggcgtacca    11160

acagtaaagg acttcttgac caaccactat cttcattttt tacgcattgc cagctcacag    11220

ctgacaggct tagggactgc tgtgcaactg tacagtgcat atgaagagaa caatagaacg    11280

tttcttttgg cagctgtgaa gcgaaatcat aatcagtatg tgaatcccag tggcgtagcc    11340

accttctttg aaagcatcaa agagatcctt ctccggcaga gtggagtaaa ggtggaatct    11400

gtggatcatg actcctgtgt gcatggccca tgtcagaatg gagggagctg tctacgaaga    11460

ttggctgtga gctccgtatt aaaaagccgt gagagtcttc cagtcatcat cgtggcaaat    11520

gaacctctgc agcctttctt atgcaagtgt ctgccaggat atgcgggtag ctggtgtgaa    11580

atagatatag atgaatgtct tccatcacct tgccacagtg gtggaacctg tcacaattta    11640

gtgggaggat tttcatgcag ctgcccagat ggcttcactg gtagggcgtg tgagagagat    11700

atcaatgagt gcctgcagag tccttgcaag aatggtgcca tctgccagaa ttttccagga    11760

agcttcaact gtgtttgcaa aactggatac acagggaaaa tgtgtgaatc ttcagtcaat    11820

tactgtgaat gcaacccctg ctttaatggt ggttcctgcc aaagtggtgt ggattcttat    11880

tattgtcatt gtccatttgg tgtctttgga aaacactgcg agttgaacag ttatggattt    11940

gaggagttat catacatgga atttccaagc ttggacccca ataacaacta tatttatgtc    12000

aaatttgcca cgattaaaag tcatgcctta ttgctttaca actatgacaa ccagacaggc    12060

gaccgggctg agtttttggc ccttgaaatt gccgaagaaa gactaagatt ctcttataat    12120

ttaggcagtg gtacatataa gctcaccacc atgaagaagg tgtcagatgg acattttcac    12180

actgtgattg ccaggagagc aggaatggca gcctccttaa ctgtggactc ctgttctgag    12240

aaccaagagc caggatattg tactgtcagt aatgtggcag tttcagatga ctggactctt    12300

gatgttcagc caaatagagt tacagttgga ggtatcagat ctctagaacc aatccttcag    12360

agaagaggac acgtggaaag ccatgatttt gttgggtgta taatggagtt tgcagtcaat    12420

ggaaggcctc tggaacccag ccaagctttg gcagcacaag gcatcctaga tcaatgccct    12480

aggctggaag gcgcttgtac tcgcagccca tgccaacatg gtggcacatg tatggattac    12540

tggtcatggc agcagtgtca ttgcaaagag ggactcactg ggaaatactg tgaaaaatct    12600

gttactcctg acactgcctt atcattagaa ggcaaagggc gcttggacta ccacatgagt    12660

cagaatgaga agcgggaata tttgttaagg caaagcttac gaggtgccat gttggagcct    12720

tttggtgtga acagtctgga agtaaaattt aggaccagaa gcgagaatgg cgttttaatc    12780

catatccaag aaagcagcaa ttacactact gtgaagatta agaatggcaa agtatatttt    12840

acatccgatg caggaattgc tgggaaagtg gagagaaata ttcctgaagt atatgttgca    12900

gacggccact ggcacacttt tctaattggg aaaaatggaa cagcaacagt attgtctgtt    12960

gacagaatat ataacagaga tattatccac cctactcagg acttcggtgg ccttgatgtg    13020

cttactatat cacttggagg aattccaccc aatcaagcac atcgagatgc ccaaacagca    13080

ggttttgatg gctgcattgc ttctatgtgg tatggtggag aaagtcttcc tttcagcggg    13140

aagcatagct tggcctccat ctcaaaaaca gatccctcag tgaagattgg ctgccgtggc    13200

ccgaacattt gtgccagcaa cccctgctgg ggtgatttgc tgtgcattaa tcagtggtat    13260

gcctacaggt gtgtccctcc tggggactgt gcctcccacc cgtgccagaa tggtggcagc    13320

tgtgagccag gcctgcactc cggcttcacc tgtagctgcc cagactcgca cacgggaagg    13380

acctgtgaga tggtggtggc ctgtcttggc gtcctctgtc ctcaggggaa ggtgtgcaaa    13440

gctggaagtc ctgcggggca tgtctgtgtt ctgagtcagg gccctgaaga gatctctctg    13500

cctttgtggg ctgtgcctgc catcgtgggc agctgcgcaa ccgtcttggc cctcctggtc    13560

cttagcctga tcctgtgtaa ccagtgcagg gggaagaagg ccaaaaatcc caaagaggag    13620

aagaaaccga aggagaagaa gaaaaaggga agtgagaacg ttgcttttga tgaccctgac    13680

aatatccctc cctatgggga tgacatgact gtgaggaagc agcctgaagg gaacccaaaa    13740

ccagatatca ttgaaaggga aaacccctac cttatctatg atgaaactga tattcctcac    13800

aactcagaaa ccatccccag cgcccctttg gcatctccag agcaggagat agagcactat    13860

gacattgaca acgccagcag catcgcccct tcggatgcag acatcattca acactacaag    13920

cagttccgca gccacacacc aaaattttca atccagaggc acagtcccct aggctttgca    13980

aggcaatccc ccatgccctt aggagcaagc agtttgactt accagccttc atatggtcaa    14040

ggtttgagaa ccagctccct aagccactca gcatgcccaa ctcccaaccc tctgtctcga    14100

cacagtccag cccctttctc caaatcttct acgttctata gaaacagccc agcaagggaa    14160

ttgcatcttc ctataaggga tggtaatact ttggaaatgc atggtgacac ctgccaacct    14220

ggcattttca actatgccac aaggctggga aggagaagca agagtcctca ggccatggca    14280

tcacatggtt ctagaccagg gagtcgccta aagcagccga ttgggcagat tccactggaa    14340

tcttctcctc cagtcggact ttctattgaa gaagtggaga ggctcaacac acctcgccct    14400

agaaacccaa gtatctgcag tgcagaccat gggaggtctt cttcagagga ggactgcaga    14460

aggccactgt ctagaacaag gaatccagcg gatggcattc cagctccaga atcctcttct    14520

gatagtgact cccatgaatc tttcacttgc tcagaaatgg aatatgacag ggagaagcca    14580

atggtatata cttccagaat gcccaaatta tctcaagtca atgaatctga tgcagatgat    14640

gaagataatt atggagccag actgaagcct cgaaggtacc acggtcgcag ggccgaggga    14700

ggacctgtgg gcacccaggc agcagcacca ggcactgctg acaacacact gcccatgaag    14760

ctagggcagc aagcagggac tttcaactgg gacaaccttt tgaactgggg ccctggcttt    14820

ggccattatg tagatgtttt taaagatttg gcatctcttc cagaaaaagc agcagcaaat    14880

gaagaaggca aagctgggac aactaaacca gtccccaaag atggggaagc agaacagtat    14940

gtgtgaagtt tatgtactgg cactataaaa tataaaaaca agaaataata ctcaaaccat    15000

tgtaaagttg ctgactaggt tgggtcacat ttgaaaaaca ggccagtatg gactagtggt    15060

ggagggaaaa ctttaaaaat aataaccaca atgctgctga aacagactca caacaactct    15120

taatttaaac atgtgtggtt gaatttattt ccctgcatgc attgtgtttt gtaactagtt    15180

atgtggcatg cagcatttgg aaaatttttc ttatttacca gtgtttgatt tgtgattttt    15240

aaaaattgat acctttacca ttgcagaaaa gaacttgtgc tttcccagtg gcgtatgtgt    15300

attgtttcaa ctgtattatt ataattatat tttgcattgc aagattcttg atgttaaacc    15360

aatccttgta aagtgtaaaa aggaaccctc ctatcgtgga atgaaagatt aagtatatta    15420

acacttttca gaatgatagt ttctgtattt gatgttgctc agaaatgtct gagtatttga    15480

gtaagtttta catgacagtg ggtactgaaa ttaagtcatt ttgttcagca ctttaacgct    15540

ttcttataga attgtcttaa aacttctgga tccttgagca aatgattata gtctcctgac    15600

tttcatgagg cttccattag gaacagaatg attgcatgtt gtccccagaa cactgccacc    15660

ttgctatgcg aatgatgttc tcagcagcac ttctaagaaa cactcttaaa agttatttat    15720

tgaaaatttt tcgtatgctt ttaatatttt aaagaattga cctaaggaaa gcttatgatt    15780

ggacttattt tccaaccaga taacatttac tctaagtacc cagtttttat aatttatatg    15840

aaatcagatt tcaacactta ctttgtcatt ttgtagatca ttttttttaa atactgtgta    15900

aaaacttttt ttacacctaa gctgtgtttt tgatactgat attttcctat gctgaatagt    15960

tttcttactt tcagggaagg taagaaaata ctttttttat atttgttact tatgtaacat    16020

tcatattttt ctcattttga tatttgtaac atactgtatg ctttctactt gtaaatgtca    16080

acaatagaat taaaatattt atttaaaata aaaa                                16114


<210>  72
<211>  4131
<212>  DNA
<213>  homo sapiens

<400>  72
ttttgtttgg ctgaggggag cgagcggcgc tttgggggag gggtcgcgta ggcgcctcac       60

ctgaccctgc ggccgtgcgg ttgctgctcc ggggcaggtc tccttccagg ccaggggccc      120

ggaatcatgt acataaagca ggtgattatc cagggttttc gaagttacag agatcaaaca      180

attgtagatc ccttcagttc aaaacataat gtgattgtgg gcagaaatgg atctggaaaa      240

agtaactttt tttatgcaat tcagtttgtt ctcagtgatg agtttagtca tcttcgtcca      300

gaacagcggt tggctttatt gcatgaaggt actggtcctc gtgttatttc tgcttttgtg      360

gagattattt ttgataattc agacaaccgg ttaccaatcg ataaagagga agtttcactt      420

cgaagagtta ttggtgccaa aaaggatcag tatttcttag acaagaagat ggtcacgaaa      480

aatgatgtga tgaacctcct tgaaagcgct ggtttttctc gaagcaatcc ttattatatt      540

gttaaacaag gaaagatcaa ccagatggca acagcaccag attctcagag attaaagcta      600

ttaagagaag tagctggtac tagagtgtat gacgaacgaa aggaagaaag catctcctta      660

atgaaagaaa cagagggcaa acgggaaaaa atcaatgagt tgttaaaata cattgaagag      720

agattacata ctctagagga agaaaaggaa gaactagctc agtatcagaa gtgggataaa      780

atgagacgag ccctggaata taccatttac aatcaggaac ttaacgagac tcgtgccaaa      840

cttgatgagc tttctgctaa gcgagagact agtggagaaa aatccagaca attaagagat      900

gctcagcagg atgcaagaga taaaatggag gatatcgaac gccaagttag agaattgaaa      960

acaaaaattt cagctatgaa agaagaaaaa gaacagctta gtgctgaaag acaagagcag     1020

attaagcaga ggactaagtt ggagcttaaa gccaaggatt tacaagatga actagcaggc     1080

aatagtgaac aaaggaaacg tttattaaaa gagaggcaga agctgcttga aaaaatagaa     1140

gaaaagcaga aagaactggc agaaacagaa cccaaattca acagtgtgaa agagaaagaa     1200

gaacgaggaa ttgctagatt ggctcaagct acccaggaaa gaacggatct ttatgcaaag     1260

cagggtcgag gaagccagtt tacatcaaaa gaagaaaggg ataagtggat taaaaaggaa     1320

ctcaagtctt tagatcaggc tattaatgac aagaaaagac agattgctgc tatacataag     1380

gatttggaag acactgaagc aaataaagag aaaaatctgg agcagtataa taaactggac     1440

caggatctta atgaagtcaa agctcgagta gaagaactgg acagaaaata ttacgaagta     1500

aaaaataaga aagatgaact acaaagtgaa agaaactact tgtggagaga agagaatgca     1560

gaacagcaag cacttgctgc taaaagagaa gatcttgaaa agaagcaaca acttcttaga     1620

gcagcaacag gaaaggccat tttaaatgga atagacagca taaacaaagt gctagaccac     1680

ttccgtcgaa aaggaataaa ccagcatgtt caaaatggct atcatggtat tgtaatgaat     1740

aactttgaat gtgaaccagc tttctacaca tgcgtggaag tcactgctgg aaacaggtta     1800

ttttatcaca ttgttgattc agatgaagtc agcacgaaga ttttaatgga gtttaataaa     1860

atgaatcttc ctggagaggt tacttttctg cctcttaaca agttagatgt cagggataca     1920

gcctatcctg aaaccaatga tgctattcct atgatcagca aactgaggta caatcccaga     1980

tttgacaaag ctttcaaaca tgtgtttgga aagactctta tttgtcgtag catggaagtt     2040

tcaacccagc tggcccgtgc tttcactatg gactgtatta ctttggaagg tgaccaagtc     2100

agccatcggg gtgctctaac tgggggttat tatgacacaa ggaagtctcg acttgaattg     2160

caaaaagatg ttagaaaagc agaagaagaa ctaggtgaac ttgaagcaaa gctcaatgaa     2220

aacctgcgca gaaatattga aaggattaat aatgaaattg atcagttgat gaaccaaatg     2280

caacagatcg agacccagca aaggaaattt aaagcatcta gagatagcat attatcagaa     2340

atgaagatgc taaaagagaa gaggcagcag tcagagaaaa ccttcatgcc taagcaacgt     2400

agcttacaga gtttggaggc aagcttgcat gctatggagt ctaccagaga gtcattgaaa     2460

gcagaactgg gaactgattt gctttctcaa ctgagtttgg aagatcagaa gagagtagat     2520

gcactgaatg atgagattcg tcaacttcag caggaaaaca gacagttgct aaatgaaaga     2580

attaaattag aaggtattat tactcgagta gagacttatc tcaatgagaa tctgagaaaa     2640

cgcttggacc aagtagaaca ggaacttaat gagctgagag agacagaagg gggtactgtt     2700

ctcacagcca caacatcaga acttgaagcc atcaataaaa gagtaaaaga cactatggca     2760

cgatcagaag atttggacaa ttccattgat aaaacagaag ctggaattaa ggagcttcag     2820

aagagtatgg agcgctggaa aaatatggaa aaagaacata tggatgctat aaatcatgat     2880

actaaagaac tggaaaagat gacaaatcgg caaggcatgc tattgaagaa gaaagaagag     2940

tgtatgaaga aaattcgaga acttggatca cttccccagg aagcatttga aaagtaccag     3000

acactgagcc tcaaacagtt gtttcgaaaa cttgagcagt gcaacacaga attaaagaag     3060

tacagccatg ttaacaaaaa ggctttggat cagtttgtaa atttctccga gcagaaagaa     3120

aagttaataa agcgtcaaga agagttagat aggggttaca aatcaatcat ggaactgatg     3180

aatgtacttg aacttcggaa atatgaagct attcagttaa ctttcaaaca ggtatctaag     3240

aacttcagtg aagtattcca gaagttagta cctggtggca aagctacttt ggtgatgaag     3300

aaaggagatg tggagggcag tcagtctcaa gatgaaggag aagggagtgg tgagagtgag     3360

aggggttctg gctcacaaag cagtgtccca tcagttgacc agtttactgg agttggaatt     3420

agggtgtcat ttacaggaaa acaaggtgaa atgagagaaa tgcaacagct ttcaggtgga     3480

cagaaatcct tggtagccct tgctctgatt tttgccattc agaaatgtga cccggctcca     3540

ttttacttgt ttgatgaaat tgaccaggct ctggatgctc agcacagaaa ggctgtgtca     3600

gatatgatta tggaacttgc tgtacatgct cagtttatta caactacttt taggcctgaa     3660

ctgcttgagt cagctgacaa attctatggt gtaaagttca gaaataaggt tagtcatatt     3720

gatgtgatca cagcagagat ggccaaagac tttgtagaag atgataccac acatggttaa     3780

ttggaaaata ctacctactg gtttgggaga tgtatatagt aatatgattc tcatacccag     3840

gaactgtaaa tttaaaccta aatatttggc caatagtttt cagacttaaa gcatcatagt     3900

ccttttatat ttgtctttgt attttataag atactctgta atgtcatgtt tgtactgata     3960

gtttaagaat ttaatttcct gtacaacttt ttgtaaaatg ttctgctcct attttaaatg     4020

ttttgaaaca tgctaaatat tctttcctaa ttattttatc acttatacta ccttttttat     4080

agcttcaatt aaataatcgg ttttatgact aaaaaaaaaa aaaaaaaaaa a              4131


<210>  73
<211>  4611
<212>  DNA
<213>  homo sapiens

<400>  73
gttacgcatg cgccctggtc accccgcggt ttgtccgcgc ctctgctacc ccctgcgcag       60

gcgctcaagg agctcttgga ctccaggttc ccgcggctgg gagaaaagga ggcggggatc      120

cgaaggggga aatgactctg aggcgcccgg acgtcgctcg gaagccaatc agagagcgtg      180

acgtcagttt ggcgcggagt ttggcggccg gggcttacag tggcgggagt tggaggcgat      240

aacgatttgt gttgtgagag gcgcaagctg cgatttctgc tgaacttgga ggcatttcta      300

cgacttttct ctcagctgag gcttttcctc cgaccctgat gctcttcaat tcggtgctcc      360

gccagcccca gcttggcgtc ctgagaaatg gatggtcttc acaataccct cttcaatccc      420

ttctgactgg ttatcagtgc agtggtaatg atgaacacac ttcttatgga gaaacaggag      480

tcccagttcc tccttttgga tgtaccttct cttctgctcc caatatggaa catgtactag      540

cagttgccaa tgaagaaggc tttgttcgat tgtataacac agaatcacaa agtttcagaa      600

agaagtgctt caaagaatgg atggctcact ggaatgccgt ctttgacctg gcctgggttc      660

ctggtgaact taaacttgtt acagcagcag gtgatcaaac agccaaattt tgggacgtaa      720

aagctggtga gctgattgga acatgcaaag gtcatcaatg cagcctcaag tcagttgcct      780

tttctaagtt tgagaaagct gtattctgta cgggtggaag agatggcaac attatggtct      840

gggataccag gtgcaacaaa aaagatgggt tttataggca agtgaatcaa atcagtggag      900

ctcacaatac ctcagacaag caaacccctt caaaacccaa gaagaaacag aattcaaaag      960

gacttgctcc ttctgtggat ttccagcaaa gtgttactgt ggtcctcttt caagacgaga     1020

ataccttagt ctcagcagga gctgtggatg ggataatcaa agtatgggat ttacgtaaga     1080

attatactgc ttatcgacaa gaacccatag catccaagtc tttcctgtac ccaggtagca     1140

gcactcgaaa acttggatat tcaagtctga ttttggattc cactggctct actttatttg     1200

ctaattgcac agacgataac atctacatgt ttaatatgac tgggttgaag acttctccag     1260

tggctatttt caatggacac cagaactcta ccttttatgt aaaatccagc cttagtccag     1320

atgaccagtt tttagtcagt ggctcaagtg atgaagctgc ctacatatgg aaggtctcca     1380

caccctggca acctcctact gtgctcctgg gtcattctca agaggtcacg tctgtgtgct     1440

ggtgtccatc tgacttcaca aagattgcta cctgttctga tgacaataca ctaaaaatct     1500

ggcgcttgaa tagaggctta gaggagaaac caggaggtga taaactttcc acggtgggtt     1560

gggcctctca gaagaaaaaa gagtcaagac ctggcctagt aacagtaacg agtagccaga     1620

gtactcctgc caaagccccc agggtaaagt gcaatccatc caattcttcc ccgtcatccg     1680

cagcttgtgc cccaagctgt gctggagacc tccctcttcc ttcaaatact cctacgttct     1740

ctattaaaac ctctcctgcc aaggcccggt ctcccatcaa cagaagaggc tctgtctcct     1800

ccgtctctcc caagccacct tcatctttca agatgtcgat tagaaactgg gtgacccgaa     1860

caccttcctc atcaccaccc atcactccac ctgcttcgga gaccaagatc atgtctccga     1920

gaaaagccct tattcctgtg agccagaagt catcccaagc agaggcttgc tctgagtcta     1980

gaaatagagt aaagaggagg ctagactcaa gctgtctgga gagtgtgaaa caaaagtgtg     2040

tgaagagttg taactgtgtg actgagcttg atggccaagt tgaaaatctt catttggatc     2100

tgtgctgcct tgctggtaac caggaagacc ttagtaagga ctctctaggt cctaccaaat     2160

caagcaaaat tgaaggagct ggtaccagta tctcagagcc tccgtctcct atcagtccgt     2220

atgcttcaga aagctgtgga acgctacctc ttcctttgag accttgtgga gaagggtctg     2280

aaatggtagg caaagagaat agttccccag agaataaaaa ctggttgttg gccatggcag     2340

ccaaacggaa ggctgagaat ccatctccac gaagtccgtc atcccagaca cccaattcca     2400

ggagacagag cggaaagaca ttgccaagcc cggtcaccat cacgcccagc tccatgagga     2460

aaatctgcac atacttccat agaaagtccc aggaggactt ctgtggtcct gaacactcaa     2520

cagaattata gattctaatc tgagtgagtt actgagcttt ggtccactaa aacaagctga     2580

gctttggtcc actaaaacaa gatgaaaaat acaagagtga ctctataact ctggtcttta     2640

agaaagctgc cttttcattt ttagacaaaa tcttttcaac gctgaaatgt acctaatctg     2700

gttctactac cataatgtat atgcagcttc ccgaggatga atgctgtgtt taaatttcat     2760

aaagtaaatt tgtcactcta gcattttgaa tgaatagtct tcacttttta aattattcat     2820

cttctctata ataatgacat cccagttcat ggaggcaaaa aacaagtttc ttgttatcct     2880

gaaactttct atgctcagtg gaaagtatct gccagccaca gcatgaggcc tgtgaaggct     2940

gactgagaaa tcctctgctg aagacccctg gttctgttct gcctccaaca tgtataattt     3000

tatttgaaat acataatctt ttcactatgc ttttgtgggg ttttttttaa gtatgtgtaa     3060

aaatgtgatg ctcagataag tacatttata tcagttcagt gttaaaatgc agtctcttga     3120

gttaaagtca tctttatttt aaatgcagtg ataaatgtca actcttcgga gaaactagga     3180

gaacaacaac agaaagctgt gtttgtcttt tttctctcaa atatatctcc cgtatgagat     3240

ttcaggtccc catgttttca ccaagcaatc tgctatgtca gccaacccaa catcactttc     3300

tacaggaggt tatgattttt gccatttact agaggaagat gttttatgaa atcaatttgg     3360

ggtttgaatt caggtgcagt catcagttct ttaggggctg caatgtttta aaaaaaataa     3420

gtcatcagat tttaagaaaa aagtgatgat ttcttattga tatttttgta acagaatata     3480

gctcttaact gaaaatccag aaccagaaac ataaatcttg agtttctttt catgtacata     3540

aaaagcaata gccttttagt atagatagcc ctgagccaaa aagtaataga attttctcta     3600

gatatttaat acagagagtg tatagactga ctctaagtta ataatgtgca aaatatctta     3660

aacatccctc cccttattca acaattatgt atcagtgatc ttgaaccatt gttttatatt     3720

tttcaccttt gtaacctcat ggaaagaggc tttacatact ttctatgtac tatttactta     3780

gaagggagcc cccttccagt catgaaactt catttgtttt atccatatcc ctgaggactg     3840

tgtagacttt atgtcagttt ttgtcattat ttgaaaatct attctgacaa ctttttaatt     3900

cctttgatct tataagttaa agctgtaaca actgaaattg catggatcaa gtaagcatag     3960

ttttatccag ggagaaaaat aaaaggaagc catagaattg ctctggtcaa aaccaagcac     4020

accatagcct taactgaata tttaggaaat ctgcctaatc tgcttatatt tggtgtttgt     4080

tttttgactg ttgggctttg ggaagatgtt atttatgacc aatatctgcc agtaacgctg     4140

tttatctcac ttgctttgaa agccaatggg ggaaaaaaat ccatgaaaaa aaaaagattg     4200

ataaagtaga tgattttgtt tgtatcccta cccatctcct ggcagcccta ctgagtgaaa     4260

ttgggataca tttggctgtc agaaattata ccgagtctac tgggtataac atgtctcact     4320

tggaaagcta gtacttttaa atgggtgcca aaggtcaact gtaatgagat aattatccct     4380

gcctgtgtcc atgtcagact ttgagctgat cctgaataat aaagcctttt accttatctg     4440

atgtcctttt ctgagctttt tgcattacct agaagcagtc tacaaaaaag aactatagta     4500

gtcaagaatc ccttctactt gttcattaaa atgtttattc ccaaagttat aatctatttc     4560

aagctgaaag agcttttaat aaaaaacatc ttgcttgaaa aaaaaaaaaa a              4611


<210>  74
<211>  5795
<212>  DNA
<213>  homo sapiens

<400>  74
gagcagcggc agcagcagcg gaccccggcg gcggcggcgg cgcgcggtcc cagccaggcg       60

gccccggtgt cccggccccg gtggatgcac ggctggggag gagcccatgg gccggagctg      120

aggctgcccg gggcggcggg gcgcggggca gggggcgcgg tcgaggcccg gaggcggcgg      180

cgcaggagga agcggaggag gtcgggcgct cggggcccgg gaggcgggcc gcgcagcgcc      240

gcagccccgg gctcgccatg ctcctggcct cggccgtggt ggtctgggaa tggctgaacg      300

agcacggccg ctggcgtccc tacagcccag cggtgagcca ccacatcgag gcggtggtcc      360

gcgccggccc ccgcgcgggg ggcagcgtgg tgctgggcca ggtggacagc cgtctcgcgc      420

cctacatcat cgacctgcag tccatgaacc agttccgcca agacacggga actctccgcc      480

cagttcgccg caactactac gacccctcct cggcccctgg gaagggcgtg gtgtgggagt      540

gggagaacga caatggctcc tggacgccct acgacatgga agtgggcatc accatccagc      600

atgcctatga gaagcagcac ccctggatcg acctcacttc cattggcttt agctacgtaa      660

ttgacttcaa caccatgggc cagatcaacc gtcagaccca gcgccaacgc cgcgtccgcc      720

ggcgcctcga cctcatctac cccatggtca cagggacctt gcctaaggct cagtcctggc      780

cagtcagccc tgggccagcc acctcgcccc ccatgtcccc ctgctcctgt ccccagtgtg      840

tcttggtgat gagtgttaag gcagccgtgg tcaatggcag cactgggccc ctacagctgc      900

cagtgacccg caagaacatg ccgcctcctg gagtggtcaa gctaccccca ctgccaggct      960

ctggggccaa gccactggac agcacaggca ccattcgagg cccactgaag accgccccat     1020

cgcaggtgat ccggagacaa gcctccagca tgcccactgg gacaaccatg ggctctcctg     1080

ccagtccccc aggacccaac agcaagaccg gaagggtggc cctggccacc ttgaatcgta     1140

ccaacctgca gcgactggcc attgcccagt cccgggtgct gatcgcctct ggggtcccca     1200

cagtcccagt gaagaaccta aatgggtcca gtcctgtcaa ccctgccttg gcaggaatca     1260

ctgggatcct catgagtgca gcggggctgc ctgtgtgtct caccaggcca ccaaagctgg     1320

tcctacaccc accccccgtc agcaagagtg aaataaaatc catcccaggg gtttccaaca     1380

caagccgcaa gaccaccaaa aaacaagcca agaaaggtaa aaccccagag gaagtgctaa     1440

aaaaatatct acagaaagtc cggcacccac cagatgagga ctgcaccatc tgtatggaac     1500

gcctcacggc cccctcaggc tacaagggcc cgcagcctac ggtaaaacct gacctggtag     1560

ggaagctgtc cagatgcggc cacgtctacc acatctactg cttggttgcc atgtacaaca     1620

atgggaacaa ggatggaagt ttgcagtgtc caacctgcaa gaccatttat ggggtgaaga     1680

caggcaccca acctccaggg aagatggagt accacctcat cccccactcc ttgcctggcc     1740

acccagactg caaaaccatc cggatcatct acagcatccc ccccggcatt cagggaccgg     1800

aacacccgaa tcctgggaag agtttcagcg cccgaggctt cccacgacac tgttaccttc     1860

cggacagcga gaaagggaga aaagttctga agctgctgct cgtggcctgg gatcgccgcc     1920

tcatttttgc cattggcacc tccagcacca caggcgagtc agacaccgtc atctggaatg     1980

aggtccacca caagacagag tttggctcta atctcactgg ccatggctac ccagatgcca     2040

attacctgga taatgtgctg gctgaactgg ctgcccaggg catctctgag gacagcactg     2100

cccaggagaa ggactgaggc cagaaaagct ttgaggtggg aggggccatg gagactgcag     2160

gacaggaagt gaggagagtg agtcaatgta gaagaagttg gtgtcctgcc ctcccaactt     2220

tctatcctcc cctcctgccc tgtgtccatc cctcatccct cccaaccaca gtgggagcca     2280

gactgaatat agcgacatca ttcataaatc tcatccaaca caaagggaga tgggatgagg     2340

gccatcctgg gtctgttccc atggagtttt tggtgctggg taggcaggaa tcccctccct     2400

accccacctc ccaagtaggg gcatggtcag cacacctagg gtatgggcag tgcttaggca     2460

ctccatatcc tggctttggg aagccggggt ttcttgcctc agccggcttc ttgctacttc     2520

cactctgctt tgagactgga gtttctgcta ttctccctct gctggaggca gggagctctc     2580

actgtgcaag gttggggggt gggcaaaggg gtgaatcact aaactgctgt gacatcagaa     2640

actgatgcct tggtgtagag caaggaagca cttcttccca agagggtcgg agaaggaaaa     2700

gcctctggga gcacattctg ctgtcatcac agtccttggc ttctctgggc cctcctctcc     2760

tcctcacagc tctcacctgt ccaaagaggc atctggttct ctcatgtgga tggatggact     2820

ctggggttcc tctttggagt ggcatcccat gatgctgttt ctagaccctc tctgatcaaa     2880

ccagagcctg catcccactg agcatctgaa ctgtcctcag ggagaggagc ccacagcctt     2940

cttcccaact cattctagac cagctcaaag attccatgag tttcatcgag tcactgtgag     3000

tggagcccat gctgggctct gtgccctctg tgtctgtgca tgcgcgtgtg tgtgtgggcg     3060

tgtgtgcatt gctgggccag cttgaaggga aggcccgtca tgtccctgca ctctgttttg     3120

caagatgcca aaccccagtt ctgatggggc tccaacagcc aggctgtggt cctttgacgt     3180

tcctcacctg ttgccaacct atcccgtagt gaactgaaac cccaatgaag acagaactgt     3240

gcctggggag atgcaatgag gtgagggctg aactcatcct tttatatttc ttttcaagat     3300

tggatcagag ctcatctcca tccagtcttg tttctatgaa ggcttcaatc tgtttccatg     3360

caaatttgct aatcagagcc cagagctgct gggtccctca tctccctcat ctattataga     3420

ttgacttaca gcagggagag aatctcttta gctcattcct aatggagttg ggatcacaat     3480

atggtctggt ccaatctgca tcttgttgtg tcccaagacc ctatctcctc cccaacattc     3540

ttattgcctt tggctcccag taaggaacga attgggggcc agggaggaga acagggggga     3600

tcaagaaggg aaacccaatt ccccctttga aagtgggttc tttgaactat gtgtttgggg     3660

gaagttcctc tggatactaa tttgaattta tatacctcat gttttggggg tttgacgtat     3720

atatatatat atatatatgc atatatattt cataatattt ggaaggtttt tgatgctaga     3780

aaaatggaaa caagagaacc ttcaaaaatg gtacttagat gggaactgga ggccaatctt     3840

tcataaagcc agccccatag ctgcttgctg ttaggcctcc agccattttg acattggggt     3900

ggatagtcga ttcacctgcc tgtcagtcga ttcacctgcc tgtcacccag ttctgtggat     3960

gtgctggtgc tgagcctttg ctctctttcc aaatggttac agggatgttg atcagctcca     4020

ccagagggag ctctgatggg aggaattgct ctgccatcct tgtccctgtg tctcctgtcg     4080

gcaggcagcc attgtatctc accagcagac caggagactg gtcccaaggt tactgcacca     4140

cagggcaatt tcctgccata gttaggaagg aaacacctga actaaatgga agagacatcc     4200

ctgcggtgtt taatatcaca cccatgccct ttgtcaggtt accatgtaca gagattactt     4260

ggagagcctc atgccgtctc taccttcgca cactggtcaa gtatctgctg agcttcttgg     4320

ccgcaaggat gcagaaatag gctgagggtc catgggaaga aagacacaat gaggcagtag     4380

gaggtgggga agaaaagaag acagactttc aaaatggaat taggcactgg ggagagatca     4440

gtttccccac atcagggaga agaaggtata ggtggggaag ggggtggcca ggagcagaag     4500

gaagaagact caagatggaa agggagccgc tgtgcctgtg gcaataccac ttggagaggt     4560

cgacttcata ccttcaagcc ttttcccctg ggcttttgat tgtgtctgtg ccccctttct     4620

tgtcctctct gcagatgccc agtaggggct acctcatcct cgtgctgttc ttgtgtggct     4680

ttctgggcag tagggatctt gaatttcctt tctaacactg tgcccggcaa ggcggggagc     4740

attcctctgc cctttgtctt gtgccaacct ggaaaggtgc agtctagatt tcagtgagaa     4800

ccctgccagc tgagccctgt gcatctacta ccttgacaca gagtgttttc ccactagaag     4860

ctctgctctg ctctcctggc ccaagtaggg gattccatgc cttccctttc atggtcttag     4920

caccagcagc ctagtttctc ccttccagag tctccaggga tgacaaattg gattggagac     4980

aaacctcgtc agatgctcat cccctaaaag gttaattgtg tatttgtggc tgcgtgtgcc     5040

tttgtgtttt cattctcttc ccatttttgt acattttggt cttctctgtg gttttatact     5100

tggtcaaaag tactcgtctt ggtattgcac tgttgtgtgc atgagaaaac tgggggaagg     5160

ctcactggta caagaaagga cccctgaccc ctttccttct ctgtggtccc cggcattaga     5220

ttgggggttc tgggagaggc aggtgaatgt cctaagtgaa ttgttctgtt tgtaactgga     5280

atgtttttga agtctttggt gttgctccgt gaaaggacat cgccacctgg tgctcatgag     5340

gtgtctttgc agaacaataa atggcaaatg aacaaccaca aaattgttac tcttgttggc     5400

cttctgctgt ttgtagatta gtgcacctat ctgtgaggga tttgggttac ctccctgagt     5460

ctgtaagcaa ccacaagccc tgccactggg tgggggaagt ccctccccaa ccacttaaaa     5520

acaaattttc cacatattac ccacccacac atttgacctg gctagacttt gtttgcctaa     5580

aggaacagac cacattgctg ggaaaatgag taagtgaacg tgtgggagaa aaacactttt     5640

agaatcacga atattcactt ttaaaggtct ctttgcctgg ctgcaatata gtgtgtgttt     5700

aaattattta caggctgttg tttctcaaat aaatgtttaa tattaatcat tcccaaactg     5760

acaagaacac aaaaataaaa tgcaaataca gagcc                                5795


<210>  75
<211>  1752
<212>  DNA
<213>  homo sapiens

<400>  75
agcgcggtga gtttgaaact gctcgcactt ggcttcaaag ctggctcttg gaaattgagc       60

ggagagcgac gcggttgttg tagctgccgc tgcggccgcc gcggaataat aagccgggat      120

ctaccatacc cattgactaa ctatggaaga ttataccaaa atagagaaaa ttggagaagg      180

tacctatgga gttgtgtata agggtagaca caaaactaca ggtcaagtgg tagccatgaa      240

aaaaatcaga ctagaaagtg aagaggaagg ggttcctagt actgcaattc gggaaatttc      300

tctattaaag gaacttcgtc atccaaatat agtcagtctt caggatgtgc ttatgcagga      360

ttccaggtta tatctcatct ttgagtttct ttccatggat ctgaagaaat acttggattc      420

tatccctcct ggtcagtaca tggattcttc acttgttaag gtagtaacac tctggtacag      480

atctccagaa gtattgctgg ggtcagctcg ttactcaact ccagttgaca tttggagtat      540

aggcaccata tttgctgaac tagcaactaa gaaaccactt ttccatgggg attcagaaat      600

tgatcaactc ttcaggattt tcagagcttt gggcactccc aataatgaag tgtggccaga      660

agtggaatct ttacaggact ataagaatac atttcccaaa tggaaaccag gaagcctagc      720

atcccatgtc aaaaacttgg atgaaaatgg cttggatttg ctctcgaaaa tgttaatcta      780

tgatccagcc aaacgaattt ctggcaaaat ggcactgaat catccatatt ttaatgattt      840

ggacaatcag attaagaaga tgtagctttc tgacaaaaag tttccatatg ttatatcaac      900

agatagttgt gtttttattg ttaactcttg tctatttttg tcttatatat atttctttgt      960

tatcaaactt cagctgtact tcgtcttcta atttcaaaaa tataacttaa aaatgtaaat     1020

attctatatg aatttaaata taattctgta aatgtgtgta ggtctcactg taacaactat     1080

ttgttactat aataaaacta taatattgat gtcaggaatc aggaaaaaat ttgagttggc     1140

ttaaatcatc tcagtcctta tggcagtttt attttcctgt agttggaact actaaaattt     1200

aggaaaatgc taagttcaag tttcgtaatg ctttgaagta tttttatgct ctgaatgttt     1260

aaatgttctc atcagtttct tgccatgttg ttaactatac aacctggcta aagatgaata     1320

tttttctact ggtattttaa tttttgacct aaatgtttaa gcattcggaa tgagaaaact     1380

atacagattt gagaaatgat gctaaattta taggagtttt cagtaactta aaaagctaac     1440

atgagagcat gccaaaattt gctaagtctt acaaagatca agggctgtcc gcaacaggga     1500

agaacagttt tgaaaattta tgaactatct tatttttagg taggttttga aagctttttg     1560

tctaagtgaa ttcttatgcc ttggtcagag taataactga aggagttgct tatcttggct     1620

ttcgagtctg agtttaaaac tacacatttt gacatagtgt ttattagcag ccatctaaaa     1680

aggctctaat gtatatttaa ctaaaattac tagctttggg aattaaactg tttaacaaat     1740

aaaaaaaaaa aa                                                         1752


<210>  76
<211>  1772
<212>  DNA
<213>  homo sapiens

<400>  76
gggctccggc ctcagaggct gtgacaatgg actatgactt taaagtgaag ctgagcagcg       60

agcgggagcg ggtcgaggac ctgtttgaat acgagggctg caaagttggc cgaggcactt      120

atggtcacgt ctacaaagcc aagaggaaag atgggaagga tgataaagac tatgctttaa      180

aacaaataga aggaactggg atctctatgt cggcatgtag agaaatagca ttacttcgag      240

agcttaagca tccaaacgtc atttctcttc aaaaggtgtt tctgtctcat gctgatagga      300

aggtgtggct tctgtttgac tatgctgaac atgacctctg gcatataatc aagtttcaca      360

gagcttctaa agcaaacaag aagccagttc agttacctcg gggaatggtg aagtcactat      420

tatatcagat cctagatggt attcactacc tgcatgctaa ctgggtgttg cacagagatt      480

tgaaacctgc taatatttta gttatgggtg aaggtcctga gcgaggaaga gtaaaaattg      540

ctgacatggg ctttgcccga ttatttaatt cacctttgaa gcctttagca gatttggatc      600

cagtggttgt tacattctgg taccgagccc ctgaactact tcttggagca aggcattata      660

ccaaagctat tgatatttgg gctatagggt gtatatttgc agaactacta acgtcagaac      720

caatatttca ctgtcgacaa gaggacatca aaactagtaa tccttatcac catgaccagc      780

tggacagaat attcaatgta atgggatttc ctgcagataa agattgggaa gatataaaaa      840

agatgcctga acattcaaca ttaatgaaag atttcagaag aaatacgtat accaactgca      900

gccttatcaa gtatatggaa aaacataaag ttaaaccaga tagtaaagca ttccacttgc      960

ttcagaagct gcttaccatg gacccaataa agcgaattac ctcagaacag gctatgcagg     1020

acccctattt cttagaagac ccacttccta catcagacgt ttttgccggt tgtcaaatcc     1080

cttacccaaa acgagaattt ttaacggaag aagaacctga tgacaaagga gacaaaaaga     1140

accagcagca gcagcagggc aataaccaca ctaatggaac tggccaccca gggaatcaag     1200

acagcagtca cacacaggga cccccgttga agaaagtgag agttgttcct cctaccacta     1260

cctcaggtgg acttatcatg acctcagact atcagcgttc caatccacat gctgcctatc     1320

ccaaccctgg accaagcaca tcacagccgc agagcagcat gggatactca gctacctccc     1380

agcagcctcc acagtactca catcagacac atcggtactg agctgcatcg gaatcttgtc     1440

catgcactgt tgcgaatgct gcagggctga ctgtgcagct ctctgcggga acctggtatg     1500

ggccatgaga atgtactgta caaccacatc ttcaaaatgt ccagtagcca agttccacca     1560

cttttcacag attggggtag tggcttccaa gttgtaccta ttttggagtt agacttgaaa     1620

agaaagtgct agcacagttt gtgttgtgga tttgctactt ccatagttta cttgacatgg     1680

ttcagactga ccaatgcatt tttttcagtg acagtctgta gcagttgaag ctgtgaatgt     1740

gctaggggca agcatttgtc tttgtatgtg gt                                   1772


<210>  77
<211>  7592
<212>  DNA
<213>  homo sapiens

<400>  77
gcggccgcgg ccggaggagc aatagcagca gccgtggcgg ccacggggcg gggcgcggcg       60

gtcggtgacc gcggccgggg ctgcaggcgg cggagcggct ggaagttgga ttccatgggt      120

tccaagagaa gaagagctac ctccccttcc agcagtgtca gcggggactt tgatgatggg      180

caccattctg tgtcaacacc aggcccaagc aggaaaagga ggagactttc caatcttcca      240

actgtagatc ctattgccgt gtgccatgaa ctctataata ccatccgaga ctataaggat      300

gaacagggca gacttctctg tgagctcttc attagggcac caaagcgaag aaatcaacca      360

gactattatg aagtggtttc tcagcccatt gacttgatga aaatccaaca gaaactaaaa      420

atggaagagt atgatgatgt taatttgctg actgctgact tccagcttct ttttaacaat      480

gcaaagtcct attataagcc agattctcct gaatataaag ccgcttgcaa actctgggat      540

ttgtaccttc gaacaagaaa tgagtttgtt cagaaaggag aagcagatga cgaagatgat      600

gatgaagatg ggcaagacaa tcagggcaca gtgactgaag gatcttctcc agcttacttg      660

aaggagatcc tggagcagct tcttgaagcc atagttgtag ctacaaatcc atcaggacgt      720

ctcattagcg aactttttca gaaactgcct tctaaagtgc aatatccaga ttattatgca      780

ataattaagg agcctataga tctcaagacc attgcccaga ggatacagaa tggaagctac      840

aaaagtattc atgcaatggc caaagatata gatctcctcg caaaaaatgc caaaacttat      900

aatgagcctg gctctcaagt attcaaggat gcaaattcaa ttaaaaaaat attttatatg      960

aaaaaggctg aaattgaaca tcatgaaatg gctaagtcaa gtcttcgaat gaggactcca     1020

tccaacttgg ctgcagccag actgacaggt ccttcacaca gtaaaggcag ccttggtgaa     1080

gagagaaatc ccactagcaa gtattaccgt aataaaagag cagtacaagg aggtcgttta     1140

tcagcaatta caatggcact tcaatatggc tcagaaagtg aagaagatgc tgctttagct     1200

gctgcacgct atgaagaggg agagtcagaa gcagaaagca tcacttcctt tatggatgtt     1260

tcaaatcctt tttatcagct ttatgacaca gttaggagtt gtcggaataa ccaagggcag     1320

ctaatagctg aaccttttta ccatttgcct tcaaagaaaa aataccctga ttattaccag     1380

caaattaaaa tgcccatatc actacaacag atccgaacaa aactgaagaa tcaagaatat     1440

gaaactttag atcatttgga gtgtgatctg aatttaatgt ttgaaaatgc caaacgctat     1500

aatgtgccca attcagccat ctacaagcga gttctaaaat tgcagcaagt tatgcaggca     1560

aagaagaaag agcttgccag gagagacgat atcgaggacg gagacagcat gatctcttca     1620

gccacctctg atactggtag tgccaaaaga aaaagtaaaa agaacataag aaagcagcga     1680

atgaaaatct tattcaatgt tgttcttgaa gctcgagagc caggttcagg cagaagactt     1740

tgtgacctat ttatggttaa accatccaaa aaggactatc ctgattatta taaaatcatc     1800

ttggagccaa tggacttgaa aataattgag cataacatcc gcaatgacaa atatgctggt     1860

gaagagggaa tgatagaaga catgaagctg atgttccgga atgccaggca ctataatgag     1920

gagggctccc aggtttataa tgatgcacat atcctggaga agttactcaa ggagaaaagg     1980

aaagagctgg gcccactgcc tgatgatgat gacatggctt ctcccaaact caagctgagt     2040

aggaagagtg gcatttctcc taaaaaatca aaatacatga ctccaatgca gcagaaacta     2100

aatgaggtct atgaagctgt aaagaactat actgataaga ggggtcgccg cctcagtgcc     2160

atatttctga ggcttccctc tagatctgag ttgcctgact actatctgac tattaaaaag     2220

cccatggaca tggaaaaaat tcgaagtcac atgatggcca acaagtacca agatattgac     2280

tctatggttg aggactttgt catgatgttt aataatgcct gtacatacaa tgagccggag     2340

tctttgatct acaaagatgc tcttgttcta cacaaagtcc tgcttgaaac acgcagagac     2400

ctggagggag atgaggactc tcatgtccca aatgtgactt tgctgattca agagcttatc     2460

cacaatcttt ttgtgtcagt catgagtcat caggatgatg agggaagatg ctacagcgat     2520

tctttagcag aaattcctgc tgtggatccc aactttccta acaaaccacc ccttacattt     2580

gacataatta ggaagaatgt tgaaaataat cgctaccgtc ggcttgattt atttcaagag     2640

catatgtttg aagtattgga acgagcaaga aggatgaatc ggacagattc agaaatatat     2700

gaagatgcag tagaacttca gcagtttttt attaaaattc gtgatgaact ctgcaaaaat     2760

ggagagattc ttctttcacc ggcactcagc tataccacaa aacatttgca taatgatgtg     2820

gagaaagaga gaaaggaaaa attgccaaaa gaaatagagg aagataaact aaaacgagaa     2880

gaagaaaaaa gagaagctga aaagagtgaa gattcctctg gtgctgcagg cctctcaggc     2940

ttacatcgca catacagcca ggactgtagc tttaaaaaca gcatgtacca tgttggagat     3000

tacgtctatg tggaacctgc agaggccaac ctacaaccac atatcgtctg tattgaaaga     3060

ctgtgggagg attcagctga aaaagaagtt tttaagagtg actattacaa caaagttcca     3120

gttagtaaaa ttctaggcaa gtgtgtggtc atgtttgtca aggaatactt taagttatgc     3180

ccagaaaact tccgagatga ggatgttttt gtctgtgaat cacggtattc tgccaaaacc     3240

aaatctttta agaaaattaa actgtggacc atgcccatca gctcagtcag gtttgtccct     3300

cgggatgtgc ctctgcctgt ggttcgcgtg gcctctgtat ttgcaaatgc agataaaggt     3360

gatgatgaga agaatacaga caactcagag gacagtcgag ctgaagacaa ttttaacttg     3420

gaaaaggaaa aagaagatgt ccctgtggaa atgtccaatg gtgaaccagg ttgccactac     3480

tttgagcagc tccattacaa tgacatgtgg ctgaaggttg gcgactgtgt cttcatcaag     3540

tcccatggcc tggtgcgtcc tcgtgtgggc agaattgaaa aagtatgggt tcgagatgga     3600

gctgcatatt tttatggccc catcttcatt cacccagaag aaacagagca tgagcccaca     3660

aaaatgttct acaaaaaaga agtatttctg agtaatctgg aagaaacctg ccccatgaca     3720

tgtattctcg gaaagtgtgc tgtgttgtca ttcaaggact tcctctcctg caggccaact     3780

gaaataccag aaaatgacat tctgctttgt gagagccgct acaatgagag cgacaagcag     3840

atgaagaaat tcaaaggatt gaagaggttt tcactctctg ctaaagtggt agatgatgaa     3900

atttactact tcagaaaacc aattgttcct cagaaggagc catcaccttt gctggaaaag     3960

aagatccagt tgctagaagc taaatttgcc gagttagaag gtggagatga tgatattgaa     4020

gagatgggag aagaagatag tgagtctacc ccaaagtctg ccaaaggcag tgcaaagaag     4080

gaaggctcca aacggaaaat caacatgagt ggctacatcc tgttcagcag tgagatgagg     4140

gctgtgatta aggcccaaca cccagactac tctttcgggg agctcagccg cctggtgggg     4200

acagaatgga gaaatcttga gacagccaag aaagcagaat atgaaggcat gatgggtggc     4260

tatccgccag gccttccacc tttgcagggc ccagttgatg gccttgttag catgggcagc     4320

atgcagccac ttcaccctgg ggggcctcca ccccaccatc ttccgccagg tgtgcctggc     4380

ctcccgggca tcccaccacc gggtgtgatg aaccaaggag tggcccctat ggtagggact     4440

ccagcaccag gtggaagtcc atatggacaa caggtgggag ttttggggcc tccagggcag     4500

caggcaccac ctccatatcc cggcccacat ccagctggac cccctgtcat acagcagcca     4560

acaacaccca tgtttgtagc tcccccacca aagacccagc ggcttcttca ctcagaggcc     4620

tacctgaaat acattgaagg actcagtgcg gagtccaaca gcattagcaa gtgggatcag     4680

acactggcag ctcgaagacg cgacgtccat ttgtcgaaag aacaggagag ccgcctaccc     4740

tctcactggc tgaaaagcaa aggggcccac accaccatgg cagatgccct ctggcgcctt     4800

cgagatttga tgctccggga caccctcaac attcgccaag catacaacct agaaaatgtt     4860

taatcacatc attacgtttc ttttatatag aagcataaag agttgtggat cagtagccat     4920

tttagttact gggggtgggg ggaaggaaca aaggaggata atttttattg cattttactg     4980

tacatcacaa ggccattttt atatacggac acttttaata agctatttca atttgtttgt     5040

tatattaagt tgactttatc aaatacacaa agattttttt gcatatgttt ccttcgttta     5100

aaaccagttt cataattggt tgtatatgta gacttggagt tttatctttt tacttgttgc     5160

catggaactg aaaccattag aggtttttgt cttggcttgg ggtttttgtt ttcttggttt     5220

tgggtttttt tatatatata tataaaagaa caaaatgaaa aaaaacacac acacacaaga     5280

gtttacagat tagtttaaat tgataatgaa atgtgaagtt tgtcctagtt tacatcttag     5340

agaggggagt atacttgtgt ttgtttcatg tgcctgaata tcttaagcca ctttctgcaa     5400

aagctgtttc ttacagatga agtgctttct ttgaaaggtg gttatttagg ttttagatgt     5460

ttaatagaca cagcacattt gctctattaa ctcagaggct cactacagaa atatgtaatc     5520

agtgctgtgc atctgtctgc agctaatgta cctcctggac accaggaggg gaaaaagcac     5580

tttttcaatt gtgctgagtt agacatctgt gagttagact atggtgtcag tgatttttgc     5640

agaacacgtg cacaaccctg aggtatgttt aatctaggca ggtacgttta aggatatttt     5700

gatctattta taatgaattc acaatttatg cctataaatt tcagatgatt taaaatttta     5760

aacctgttac attgaaaaac attgaagttc gtcttgaaga aagcattaag gtatgcatgg     5820

aggtgattta tttttaaaca taacacctaa cctaacatgg gtaagagagt atggaactag     5880

atatgagctg tataagaagc ataattgtga acaagtagat tgattgcctt catatacaag     5940

tatgttttag tattccttat ttccttatta tcagatgtat tttttctttt aagtttcaat     6000

gttgttataa ttctcaacca gaaatttaat actttctaaa atatttttta aatttagctt     6060

gtgcttttga attacaggag aagggaatca taatttaata aaacgcttac tagaaagacc     6120

attacagatc ccaaacactt gggtttggtg accctgtctt tcttatatga ccctacaata     6180

aacatttgaa ggcagcatag gatggcagac agtaggaaca ttgtttcact tggcggcatg     6240

tttttgaaac ctgctttata gtaactgggt gattgccatt gtggtagagc ttccactgct     6300

gtttataatc tgagagagtt aatctcagag gatgcttttt tccttttaat ctgctatgaa     6360

tcagtaccca gatgtttaat tactgtactt attaaatcat gagggcaaaa gagtgtagaa     6420

tggaaaaaag tctcttgtat ctagatactt taaatatggg aggcccttta acttaattgc     6480

ctttagtcaa ccactggatt tgaatttgca tcaagtattt taaataatat tgaatttaaa     6540

aaaatgtatt gcagtagtgt gtcagtacct tattgttaaa gtgagtcaga taaatcttca     6600

attcctggct atttgggcaa ttgaatcatc atggactgta taatgcaatc agattatttt     6660

gtttctagac atccttgaat tacaccaaag aacatgaaat ttagttgtgg ttaaattatt     6720

tatttatttc atgcattcat tttatttccc ttaaggtctg gatgagactt ctttggggag     6780

cctctaaaaa aatttttcac tgggggccac gtgggtcatt agaagccaga gctctcctcc     6840

aggctccttc ccagtgccta gaggtgctat aggaaacata gatccagcca ggggcttccc     6900

taaagcagtg cagcaccggc ccagggcatc actagacagg ccctaattaa gtttttttta     6960

aaaagcctgt gtatttattt tagaatcatg tttttctgta tattaacttg ggggatatcg     7020

ttaatattta ggatataaga tttgaggtca gccatcttca aaaaagaaaa aaaaattgac     7080

tcaagaaagt acaagtaaac tatacacctt tttttcataa gttttaggaa ctgtagtaat     7140

gtggcttaga aagtataatg gcctaaatgt tttcaaaatg taagttcctg tggagaagaa     7200

ttgtttatat tgcaaacggg gggactgagg ggaacctgta ggtttaaaac agtatgtttg     7260

tcagccaact gatttaaaag gcctttaact gttttggttg ttgttttttt tttaagccac     7320

tctccccttc ctatgaggaa gaattgagag gggcacctat ttctgtaaaa tccccaaatt     7380

ggtgttgatg attttgagct tgaatgtttt catacctgat taaaacttgg tttattctaa     7440

tttctgtatc atatcatctg aggtttacgt ggtaactagt cttataacat gtatgtatct     7500

tttttttgtt gttcatctaa agctttttaa tccaaataaa tacagagttt gcaaagtgat     7560

ttggattaac caggaaaaaa aaaaaaaaaa aa                                   7592


<210>  78
<211>  6918
<212>  DNA
<213>  homo sapiens

<400>  78
aaagtttgca ttgcaatccc cctgccttcc tctcctttct cccgatcaat gcatatttgc       60

aaaaggatta agccacagat ttaagcgccg ggagcccatt tctgccttgc aaaggagacc      120

ggactgaaaa acctaaagcc agctctgatt tcttttcgcc aagtgggaag gtggtttatt      180

tttcttgctt tttggagtca acacccttcc ccaccagccc ttatccccac cctcaccccg      240

caaccccttc acgccccctc cccctccccc tcctcatcct cccaccatcc tctaaagagg      300

caaagggatt ttttttttct tttggtcttc ttttttcccc cttccctgtt tatcctgaaa      360

aggatttgaa gacaagcttg aaggataaaa agccttggtg cttcccagga gccgagccga      420

ggagcagaag aggaagagcc gggggctgcc gtagcctttg gagatggacg agcagcccag      480

gctgatgcat tcccatgctg gggtcgggat ggccggacac cccggcctgt cccagcactt      540

gcaggatggg gccggaggga ccgaggggga gggcgggagg aagcaggaca ttggagacat      600

tttacagcaa attatgacca tcacagacca gagtttggat gaggcgcagg ccagaaaaca      660

tgctttaaac tgccacagaa tgaagcctgc cttgtttaat gtgttgtgtg aaatcaaaga      720

aaaaacagtt ttgagtatcc gaggagccca ggaggaggaa cccacagacc cccagctgat      780

gcggctggac aacatgctgt tagcggaagg cgtggcgggg cctgagaagg gcggagggtc      840

ggcggcagcg gcggcagcgg cggcggcttc tggaggggca ggttcagaca actcagtgga      900

gcattcagat tacagagcca aactctcaca gatcagacaa atctaccata cggagctgga      960

gaaatacgag caggcctgca acgagttcac cacccacgtg atgaatctcc tgcgagagca     1020

aagccggacc aggcccatct ccccaaagga gattgagcgg atggtcagca tcatccaccg     1080

caagttcagc tccatccaga tgcagctcaa gcagagcacg tgcgaggcgg tgatgatcct     1140

gcgttcccga tttctggatg cgcggcggaa gagacggaat ttcaacaagc aagcgacaga     1200

aatcctgaat gaatatttct attcccatct cagcaaccct taccccagtg aggaagccaa     1260

agaggagtta gccaagaagt gtggcatcac agtctcccag gtatcaaact ggtttggaaa     1320

taagcgaatc cggtacaaga agaacatagg taaatttcaa gaggaagcca atatttatgc     1380

tgccaaaaca gctgtcactg ctaccaatgt gtcagcccat ggaagccaag ctaactcgcc     1440

ctcaactccc aactcggctg gttcttccag ttcttttaac atgtcaaact ctggagattt     1500

gttcatgagc gtgcagtcac tcaatgggga ttcttaccaa ggggcccagg ttggagccaa     1560

cgtgcaatca caggtggata cccttcgcca tgttatcagc cagacaggag gatacagtga     1620

tggactcgca gccagtcaga tgtacagtcc gcagggcatc agtgctaatg gaggttggca     1680

ggatgctact accccttcat cagtgacctc ccctacagaa ggccctggca gtgttcactc     1740

tgatacctcc aactgatctc ccagcaatcg catcccggct gaccctgtgc cccagttggg     1800

gcaggggcag gagggagggt ttctctccca acgctgaagc ggtcagactg gaggtcgaag     1860

caatcagcaa acacaataag agtctccttc tcttctcttc tttgggatgc tatttcagcc     1920

aatctggaca cttctttata ctctcttccc ttttttttct gggtagaagc cacccttccc     1980

tgcctccagc tgtcagcctg gttttcgtca tcttccctgc ccctgtgcct ctgtcctaga     2040

ctcccggggt ccccgccctc tctcatatca ctgaaggata ttttcaacaa ttagaggaat     2100

ttaaagagga aaaaaattac aaagaaaata ataaaagtgt ttgtacgttt tcatgctggt     2160

ggtttgagga gccaaattta cctcactcga atccctcact ccctatgtta acaggcaatc     2220

cttctctgtt tctcttatta ctctcactac ctcttagcag gaatactcca cattgcccta     2280

ttcattccag gcctccctgc ttcctcttgc tcttcctccc tggggacagt actgattgga     2340

acactttcct cctcttcctt cctagcccca gctattcact ggggactgtc atagctggga     2400

ttctaaaggt gccacatttt tcagtttcat ctccactagg ttggttcccg ggcaggaagt     2460

caggcagcag ggaaggacac gggaacagca ggtggagaat tcctacagtc tttcttaccc     2520

tgctagcaat agctctcagt ttcagaggca cagtctttgg agaccattca gcactgagaa     2580

agcaatattt agaacctatt gcaaaactgg gcctgagtta ggcatggtga tgaatgcatc     2640

agcaaggaat agaaagttct tatcgtgaaa cccttcaacc tcaactatgc cttcatagac     2700

acacacgttc atgcacatgt aggcacatgt accatctcac atcttcactt tcccgagatg     2760

ccatatacaa ttacctacat taataactgt agcactatgc cttttgagcc cgagagaggg     2820

aattagtgac tctaagtgaa ggtcactgac acagagaagc agtatgtgtc tggggcttcc     2880

aggacctgca ggcccactag cgtgcactta ccagaatggc atacacagga cctgatcatg     2940

aggaagacca ggtttccagt gtaaactact cttgttccca ccacctctgg agcactcagg     3000

gagccccata cagtacttac aatgtcttta atggacttga ttctgtttaa ttttttgttt     3060

tatattaggc acactgtatt aattttccaa aatgttatac cacactatgt tcttggtcct     3120

gacctattgc tctggaggaa agagttgtat aagaacgtgg ctcatgtgaa cttttgctag     3180

cttcatttga ggacctgaga atcatgggga aagggaaggt aatgttttca ttgaaatcat     3240

cacagtgatt tttattccct gggaacacag cgtgtactaa aaatacatga gaaaatagca     3300

tgtatatgaa agctattctc aaaagtcacc tgagctcacc atcttcatag ccaaccctac     3360

cagttataaa gatggcagct ctatcacttg attaagtggg aggtggtcaa atattttggt     3420

gcctcatttt cttcatctgt gagatgggaa ctgttatgcc tggcttacta agagtcttgt     3480

gagagactga gaagttgatt ttgttcatat ccaatctgta aatgcgaagt caggggaagt     3540

aatgtccctg aaataaacgg gttcatgcca tctagggaca ataaatggtt ttcttgttgt     3600

aacttctggt taatatcagt accttgatgt catcaccgtg atgacaaaga gaagagttat     3660

tgttgatctt cttggttttg gtctgtctct tttcttagga taaagaaaaa cttccaaact     3720

agaaaaacag gccctggttc ccttagtttg cacttgaacc caatatgttg ccttgtacat     3780

acttggtccc tgtcacattg actgcttggg aggcttccag ggagaagtat gagaccctga     3840

ggggtgagaa tgggcagcta gcaagaacat ggaaattctg cttggcacta cagtcataaa     3900

tagaaaacac tgtgtgtgct caggggagca ggggatgcca ctgaagaaac tcaagggaat     3960

gtgtatttga aggaaatgca aaaactaagt atttagcaaa atgaaattat gccttgatga     4020

ctaaaaggca ctagaaaggt tgtgtctact aacttcagcc ctaatcagaa cagatgccta     4080

gaaggagcat ttttgtgaca acttcatagt gattagaatc agtggagaac tccatcttag     4140

tggcaggaat ataatgaaac tacccacgca agaacatggt tgaatcacat ttgcttgact     4200

tagggcaaag tacgaaagag agacaaaagg gttctcttgg aaacaagaag agtgactcca     4260

gatgtggcct gaataattgc catgttaagt taatgcaaaa gatcagaaca gggctacatt     4320

tgcacaggca gtttctctcc gggccgtagt tttcactgat gatcaccttt cacagcattt     4380

tccccaacca gcatttcact tagtcttctc tatacccagc acctcccccg gcacccccgg     4440

caagcccact atcacttccg acttccaacg tggcatccgt gagatctgtc cacattaggc     4500

gaagcaggag aacactgaga gcagcaggat gggtttggaa agagcatgcc tctggaaaca     4560

cagcttcctg ggaattcaca tgaggccagt cctacagaga gcaagatgca ccccaggatt     4620

tcttcatttt ctaatagatg tgggagtgct ccattttccc cgacagcgaa tttcccctga     4680

gaaacgatac tagaccctgg gtttgcccac cttgtaactc ttccttatct cctccttttc     4740

atccctaatc catcctccct ctggcatgga attgacgccc gtgcagtaca tttgccaagt     4800

ggcaccttct ttcaatttat gttttatttt gctatggtgg tgattcttta tttgctggtt     4860

gtcttttctc acacatcttt ctctctgtct ctctctttcc tgctctttgt ttttctgccc     4920

agaaaaacct gacttcgata ccaaaaaaga tgaaactaca gaaactcaaa tttaaaaaaa     4980

actttaaaag aaacaaaaaa atactcaacg attctttcag ctttattaac attttccatt     5040

gtttcttgcg acttgtgtct cgttctttgt agtattgatg atgaacattt gataatgaat     5100

gttcttgtat attcagataa agaaaaaaaa aaccaaaaaa gcggtctgaa tttaatagtg     5160

tttataataa aaattttaaa aatgaccctc atagcacgca aaacaggatg gggaatttcc     5220

cctcttcttt ctgtgacaat gcgcatcatt cctgcattag tttttaacac cagactacct     5280

acattcatca tttccctcat ttttctttta ttttcttgca tttgtgaatt agttcaagaa     5340

tgctagaaaa gtgtcgagtt gtgcacatcc atttcttgtt tcacaatgtt taaaagtgac     5400

agtaattcat tttgtaaact aaaaaaaaaa aaaaaaaggt tggaatagtg agcataatag     5460

gtacaaccta acacattatt atgtttatta actttgagac ccagaaataa attcttttct     5520

tttcttgatt cttgctctta aaaatacaaa aaaaaaaatg ttttgttttg tgttattttt     5580

ggtttgttta ttggggggct ttttttaatt gtcaggatta tgatcttgct gtttttcttc     5640

aatatgtata caaggtgatg tgaaaagatg acttgggcag aggagtaaga acaagtaggc     5700

ttgttcttct actttgcttc agaattcagt taatgccaaa agcgaagatc aagcccatgt     5760

tgatgtctcg ttgctcacct gcatttccag agagtgtgac actcatgcag tccctgagaa     5820

aaataaaatc agggacatac ttctcctttt agccttttaa aaattcaaaa acgtttagtc     5880

caagggaact ttttatgcta tcaggaaagg tttttgctgt ttttgattct gattatcaca     5940

gccaagtact ttgttttatt tctccctaat taataactac attccatgag gcctcttcca     6000

accaaagagg ccttttcttc caggagagtc ccgcaggaga tgctggtatg atgggcacca     6060

ttggttaagt aaactacatg caggaagaag tccttggggc cagtctgcca gctgagtcct     6120

ggttttggat gaagagttaa tgagatattg ggccaggctc aatgctgtag ttttaatgct     6180

aagaggttac gtttacttca cagagtacac ctcttagtaa cctctgactt aggcagctgc     6240

ttaaagcaaa ttgcaaaact ggcttgattt ggaatgtttt tattagagga aaaaagaaag     6300

ccatattatc tggaaaaaaa ttcattttaa ataccatcat tcaacaaatt atgttcagaa     6360

agtggtcaga acttaagcaa gaaaagtaaa gaaagaatgc agaattgtgg agcaatgctt     6420

taggaaatat ttctacctga acacttgtac tcttgaagtc acaacaaaat aatgatgagc     6480

ttttcacatc acctttatgg tttcaatccc tagctcaaag cttcctggaa tcttttattt     6540

tttgtaaact tttttttctt ttgttaaaat aaataaaaca ttcaatgttt ttctcctttt     6600

ctctcttatt acttctttcc tttggcattt tcaatttgaa atgctttcct ttggttgttg     6660

gttttattct ccccctaccc ctcccctttt cttattattc agaatataaa cctgcaaagc     6720

tctgctctgt tttggttttg aaagtttaag cttttctgct tctgtgagag cacaggcttc     6780

tgtccctttt gattccaact gaacttttgt gttctctaat gatactaaca cggtgtaggt     6840

tttacagtct cctaatttgt actggtaatg catattccaa ataaatagtt tcttttgttg     6900

caaaaaaaaa aaaaaaaa                                                   6918


<210>  79
<211>  7292
<212>  DNA
<213>  homo sapiens

<400>  79
ctctgcgctg cccggtgggg cggggaaaga agccctgagc cgggatctgg cactcccagg       60

actcccggcc ggggtagctc ttcactcctc agcgcgacgt cgtgtcgagt tcccaaaaag      120

ctccgcaggg gctgtaggga ggcatacaag aattaaattc tgaataagtc tgcaggtagg      180

atggacagtt attttaaagc agctgtcagt gacttggaca aactccttga tgattttgaa      240

cagaacccag atgaacaaga ttatctccaa gatgtacaaa atgcatatga ttctaaccac      300

tgctcagttt cttcagagtt ggcttcctca cagcgaactt cattgctccc aaaagaccaa      360

gagtgcgtta atagttgtgc ctcatcagaa acaagctatg gaacaaatga gagttccctg      420

aatgaaaaaa cactcaaggg acttacttct atacaaaatg aaaaaaatgt aacaggactt      480

gatcttcttt cttctgtgga tggtggtact tcagatgaaa tccagccgtt atatatggga      540

cgatgtagta aacctatctg tgatctgata agtgacatgg gtaacttagt tcatgcaacc      600

aatagtgaag aagatattaa aaaattattg ccagatgatt ttaagtctaa tgcagattcc      660

ttgattggat tggatttatc ttcagtgtca gatactccct gtgtttcttc aacagaccat      720

gatagtgata ctgtcagaga acaacagaat gatatcagtt ctgaattaca aaatagagaa      780

atcggaggaa tcaaagaatt gggtataaaa gtagatacaa cactttcaga ttcctataat      840

tacagtggaa cagaaaattt aaaagataaa aagatcttta atcagttaga atcaattgtt      900

gattttaaca tgtcatctgc tttgactcga caaagttcca aaatgtttca tgccaaagac      960

aagctacaac acaagagcca gccatgtgga ttactaaaag atgttggctt agtaaaagag     1020

gaagtagatg tggcagtcat aactgccgca gaatgtttaa aagaagaggg caagacaagt     1080

gctttgacct gcagccttcc gaaaaatgaa gatttatgct taaatgattc aaattcaaga     1140

gatgaaaatt tcaaattacc tgacttttcc tttcaggaag ataagactgt tataaaacaa     1200

tctgcacaag aagactcaaa aagtttagac cttaaggata atgatgtaat ccaagattcc     1260

tcttcagctt tacatgtttc cagtaaagat gtgccgtcct cattgtcctg tcttcctgcg     1320

tctgggtcta tgtgtggatc attaattgaa agtaaagcac ggggtgattt tttacctcag     1380

catgaacata aagataatat acaagatgca gtgactatac atgaagaaat acagaacagt     1440

gttgttctag gtggggaacc attcaaagag aatgatcttt tgaaacagga aaaatgtaaa     1500

agcatactcc ttcagtcatt aattgaaggg atggaagaca gaaagataga tcctgaccag     1560

acagtaatca gagctgagtc tttggatggt ggtgacacca gttctacagt tgtagaatct     1620

caagaggggc tttctggcac tcatgtccca gagtcttctg attgttgtga aggttttatt     1680

aatacttttt caagcaatga tatggatggg caagacttag attactttaa tattgatgaa     1740

ggcgcaaaaa gtggcccact aattagtgat gctgaacttg atgcctttct gacagaacag     1800

tatcttcaga ccactaacat aaagtctttt gaagaaaatg taaatgactc taaatcgcaa     1860

atgaatcaga tagatatgaa aggcttagat gatggaaaca tcaataatat atatttcaat     1920

gcagaagcag gagctattgg ggaaagtcat ggtattaata taatttgtga aacagttgat     1980

aaacaaaata caatagaaaa tggcctttct ttaggagaaa aaagcactat tccagttcaa     2040

caagggttac ctaccagtaa gtctgagatt acaaatcaat tatcagtctc tgatattaac     2100

agtcaatctg ttggaggggc cagacctaag caattgttta gccttccatc aagaacaagg     2160

agttcaaagg acctgaataa gccagatgtt ccagatacaa tagaaagtga acccagcaca     2220

gcagataccg ttgttccaat cacttgtgct atagattcta cagctgatcc acaggttagc     2280

ttcaactcta attacattga tatagaaagt aattctgaag gtggatctag tttcgtaact     2340

gcaaatgaag attctgtacc tgaaaacact tgcaaagaag gcttggtttt gggccagaaa     2400

cagcctactt gggttcctga ttcagaagct ccaaactgta tgaactgcca agtcaaattt     2460

acttttacca aacggcgaca ccattgccga gcatgtggga aagtattttg tggtgtctgt     2520

tgtaatagga agtgtaaact gcaatatcta gaaaaggaag caagagtatg tgtagtctgc     2580

tatgaaacta ttagtaaagc tcaggcattt gaaaggatga tgagtccaac tggttctaat     2640

cttaagtcta atcattctga tgaatgtact actgtccagc ctcctcagga gaaccaaaca     2700

tccagtatac cttcaccagc aactttgcca gtctcagcac ttaaacaacc aggtgttgaa     2760

ggactatgtt ccaaagaaca gaagagagta tggtttgcag atggtatatt gcccaatggt     2820

gaagttgcag atacaacaaa attatcatct ggaagtaaaa gatgttctga agactttagt     2880

cctctctcac ctgatgtgcc tatgacagta aacacagtgg atcattccca ttctactaca     2940

gtggaaaagc caaacaatga gacaggagat attacaagaa atgagataat tcagagtcct     3000

atttctcagg ttccatcagt ggaaaaattg tctatgaaca caggaaatga ggggttacct     3060

acttctggtt catttacact agatgatgat gtttttgcag aaactgaaga accatctagt     3120

cctactggtg tcttagttaa cagcaattta cctattgcta gtatttcaga ttataggtta     3180

ctgtgtgata ttaacaagta tgtctgcaat aagattagtc ttctacctaa tgatgaggac     3240

agtttgcccc cacttctggt tgcatctgga gaaaagggat cagtgcctgt agtagaagaa     3300

catccatctc atgagcagat cattttgctt cttgaaggtg aaggctttca tcctgttaca     3360

tttgtcctaa atgctaatct actcgtgaat gtcaaattca tattttattc ctcagacaaa     3420

tattggtact tttcaaccaa tggattgcat ggcttgggac aggcagaaat tattattcta     3480

ttgttatgtt tgccaaatga agatactatt cctaaggaca tcttcagact atttatcacc     3540

atatataagg atgctctaaa aggaaaatac atagaaaact tggacaatat tacctttact     3600

gagagttttc tcagtagcaa ggatcacgga ggattcctgt ttattacacc tacttttcag     3660

aaacttgatg atctctcatt accaagtaat ccttttcttt gtggaattct tatccagaag     3720

cttgagattc cctgggcaaa ggtttttcct atgcgtttaa tgttgagatt gggtgcagaa     3780

tataaagcat atcctgctcc tctaacaagc atcagaggcc gaaaacctct ttttggagaa     3840

ataggacaca ctattatgaa cttacttgtt gaccttcgaa attaccagta taccttgcat     3900

aatatagatc aactgttgat tcatatggaa atgggaaaaa gctgcataaa aataccacgg     3960

aaaaagtaca gtgatgtaat gaaagtacta aattcttcca atgagcatgt cattagcatt     4020

ggagcaagtt tcagtacaga agcagattct catctagtct gtatacagaa tgatggaatt     4080

tatgaaacac aggccaacag tgccactggc catcctagaa aagtgacagg tgcaagtttt     4140

gtggtattca atggagctct aaaaacatct tcaggatttc ttgctaagtc cagcatagtt     4200

gaagatggct taatggtaca aataactcca gagaccatga atggcttgcg gctagcttta     4260

cgagaacaga aagactttaa aattacatgt gggaaagttg atgcagtaga cctgagagaa     4320

tacgtggata tctgctgggt agatgctgaa gaaaaaggaa acaaaggagt tatcagttca     4380

gtggatggaa tatcattaca aggatttcca agtgaaaaaa taaaactgga agcagatttt     4440

gaaaccgatg agaagattgt aaaatgtacc gaggtgttct actttctaaa ggaccaggat     4500

ttatctattt tatcaacttc ttatcagttt gcaaaagaaa tagccatggc ttgtagtgct     4560

gcgctgtgcc ctcacctgaa aactctaaaa agtaatggga tgaataaaat tggactcaga     4620

gtttccattg acactgatat ggttgaattt caggcaggat ctgaaggcca acttctgcct     4680

cagcattatc taaatgatct tgatagtgct ctgatacctg tgatccatgg tgggacctcc     4740

aactctagtt taccattaga aatagaatta gtgtttttca ttatagaaca tcttttttag     4800

tgaaagaatg tgccatatta catattgcaa cctaatttgt taaaactaac tccagcacta     4860

aagctgaaat gccacaaaca ctaaaagtat aaatatgtct gatttttgaa acacataagc     4920

tttgctcttt aggcaggaat gatcttttca aatcattagc acaatattta aatatctaaa     4980

aatttaagag atccatactt tctgtagctt tacaattaat ttaagtacta aaaagacaag     5040

gatttctttt aagaaattta tagcatttac tgtgttattt aaatgctaag ccaaagtatc     5100

tgcacttagg tatacctctt tatgccaata atgattttaa tgaaggctct tttcagatgt     5160

aaccttatga aggaaatatc tgctttgtgt atatgccagt tagaatactg gtttctaaag     5220

tctgtcaaat tgtatttcag tggcacaaaa accagttttg aggtcttaga cttataattc     5280

tttgaataaa actgataact tatttgtata attggagtgg agacctacct ccataattag     5340

ataaactctt tttggattat aatcagaatt ttgccttttt tcttctcaaa ttattacata     5400

tgtatgtatt atatatccac atatatagtt ttccctgatt aaatggatat taaaataatt     5460

gcgggtgctt caggactttt tgcttctata tttaagtata ttgtttttat agcaagaaca     5520

tattctgaat gttttataaa tctttaataa tttatatgta ggtaatattt ttgtatcaca     5580

atgcattatt tttttcctcc tttccttcca aactatacca ctgtatttac cacttctaag     5640

agtgactgac gacgggccag atgacccttg aagtagtcat tatgtagcaa taaatgaagc     5700

ctgaaacagg tttttttact tccactttaa tccttagaaa tttcttggca acttcgcata     5760

ttttcattga caccagtgta taagtataaa tttaaatgaa ctaattactt ttgcatattt     5820

taaattcttt atatggtagt tattttttat aacaggatat taacataagt taaatcctat     5880

gtatttgaaa ttgttacaga gctttcctct ttacttcaaa cagcaaaaaa gtggggggca     5940

tattgtagtc ctgtcattta agttatgtaa aaaatttaat cattattttg atgctttaaa     6000

cattctcatg tgtaatatat gtttttgtat caaaaacact catatatttc aagaaaaaga     6060

aattatgtta aatagccctg ttttaagaaa aatatttatg aagcatctca acttgaagat     6120

caagtcaaag ttataactca ggatctgagg tctcaagcta ggagagactg agaattttaa     6180

tcagtttggg catatagttt ggactgaatc acatctgtag tacttagcca aagacaattt     6240

ggaggagaat atcagccttc tggaagtagc tacttcctga acaatgtaaa gtgtcgcaga     6300

tattcaataa aatggcaacc tgttataatt tgtgaaattt attgaaatgg tgtaagatga     6360

aaacaattgc atatcaaacc caatttatgt tttctaaata tagtgtatgt attctgccat     6420

gtaagtaatt gaacagtctt aaaataacca aatggtagag ggctgttcca tgatgggaca     6480

gctttggatt tgttttcata aaatctctat attcaataaa aattggaatt atgtgcctga     6540

agtttggagg cacattttga agtattcttt gtagacatat agtatgtttc tgaatgtgtt     6600

tgttacttat ttggtcattg gtacttaatt tgaaatttta attttttaag agaagaaata     6660

gaatggttct ttgtactcag tctgcaatga tctatttttg gcttatgtct tttaatacta     6720

ctctctttct ctgaattttg aaatatgaag taaaatctag cccatttgtt ttatgcagct     6780

attcaacaaa ctttgtgtgt tcgtatactt gctacatgca gagcacttta ccaggtttct     6840

aagcaaaaat ttctaaaaat gattaattgt tctgacagaa ttaggcgtag ttctttatca     6900

acatttatgg attccatgcc acaagtagta tgcgcttaag tgcagagcat gccaagagaa     6960

agagtaggat ttggccctgt aggagcaaag attcaattgt gggaaactac ttgtttctga     7020

aaattgcatg ctaggatatt tacatcatgt tcctgttgaa aacaattcct gattaaaata     7080

caagaataat cttaaaacat caaagagatt ttccagacaa taaggaatgc caagtccaaa     7140

agtaaagaga ataagagaag caagcatgta cccttactct gacaacctta tgagtgaggg     7200

ggacagaaat taaagttcag ggcccatata aggtgatgaa cctaacagga gaccctccac     7260

acaataggct gagactccca aatactttca cc                                   7292


<210>  80
<211>  7629
<212>  DNA
<213>  homo sapiens

<400>  80
gcggccgcgg aggcggaggc agccgcggag gcggaggcgg ccggcggggg gtggcgaggg       60

gcgccgggcc cccgcggacc tgtcgtcctc ggcccgtcct ccggccccgg ccccgcgcgg      120

ctgaggaggc gcggccagga ccatgtcggc gggcggccgt gacgaggagc ggcggaagct      180

ggccgacatc atccaccact ggaacgccaa ccggctggac ctgttcgaga tcagccagcc      240

gaccgaggat ttggagttcc atggagtgat gagattttat tttcaagata aagctgctgg      300

aaactttgca acaaaatgta ttcgggtctc tagtactgcc accactcaag atgtaatcga      360

aacgctcgcg gagaaatttc gacctgatat gcgaatgctg tcctctccca agtattcact      420

ctatgaagtg catgtcagcg gagaaagaag attggatata gatgagaaac ctctagttgt      480

acaactgaat tggaacaaag atgatcggga aggcagattt gttcttaaga atgagaatga      540

cgccattcct cctaagaagg ctcaaagtaa tggacctgaa aagcaggaaa aagaaggggt      600

tatccagaac ttcaagagaa ctctctcaaa gaaagaaaag aaggaaaaaa agaagagaga      660

aaaagaggca ttgcgacagg catctgataa agatgataga cctttccaag gggaggatgt      720

tgaaaattct cgactggctg ctgaggttta caaagacatg ccggaaacca gctttactcg      780

aaccatttct aatcctgagg tggttatgaa acgacggagg cagcaaaaat tggaaaagag      840

aatgcaggaa tttcggagct cagatgggcg gcctgattca ggtggaacat tgagaattta      900

tgcagatagt ttaaaaccaa atattcccta caagacaatc ctgctgtcta ctacagatcc      960

tgcagacttt gctgtggctg aagctttaga gaagtatggt ctggaaaaag aaaaccctaa     1020

ggattactgc atcgcccggg ttatgcttcc tcctggagcc cagcattctg atgaaaaggg     1080

tgctaaagaa attattcttg atgatgatga gtgtccttta caaatcttca gggaatggcc     1140

aagtgacaaa gggattttag tctttcagtt gaagaggagg ccaccagacc acatcccaaa     1200

gaaaaccaag aaacacttgg aaggcaagac acccaaggga aaggagagag ctgacgggtc     1260

tggctatggc tccacccttc ctccggagaa gctgccctat ttagtagagt taagcccagg     1320

gagaaggaat cactttgcct actacaacta tcacacttac gaagatggtt ctgactctag     1380

agataagcca aagctttacc gccttcagtt aagtgttact gaagttggga cagaaaagtt     1440

ggatgacaac tctatccagt tgtttggccc aggaattcag ccccatcact gtgaccttac     1500

caacatggat ggagtggtca ctgtgacgcc cagaagtatg gacgcagaaa cctacgtgga     1560

aggccagcgc atctcagaaa ccaccatgct gcagagtggc atgaaagtgc agtttggggc     1620

gtcccatgta tttaagtttg tggaccccag tcaggatcat gctcttgcaa aaagatctgt     1680

ggatggaggc ctgatggtta agggcccaag acataaacct ggaattgttc aggagacaac     1740

ttttgatttg ggaggagata ttcatagtgg gacagcatta ccgacaagca agagcaccac     1800

taggctggac agcgacagag tgtcgtctgc ctctagcaca gccgagcggg gaatggtgaa     1860

gccgatgatc agagtagaac agcagccaga ttatcgcagg caagaaagca gaacacagga     1920

tgcttctggg cctgagctga tactacctgc aagcattgaa ttcagggaaa gttctgaaga     1980

ttcatttttg tctgccatta taaattatac taatagctct acagtccact ttaagttgtc     2040

ccctacatat gtattatata tggcatgccg gtatgtattg tccaaccagt acagacctga     2100

catcagccct acagagcgca cacataaagt cattgcagtc gtcaacaaga tggtgagcat     2160

gatggagggt gtcatccaga aacagaagaa tattgcaggg gcacttgcct tctggatggc     2220

aaatgcatct gaacttctca acttcattaa gcaagaccga gaccttagtc ggatcacact     2280

ggatgctcaa gatgttttag cacatttggt tcaaatggca tttaaatact tggttcactg     2340

tcttcaatca gaacttaata attacatgcc agcctttcta gatgaccctg aagagaacag     2400

tctgcaacga ccaaaaatag atgatgtgct gcacacgctc acaggagcca tgtccttgct     2460

acgacgctgc agagtcaatg ccgccctgac catccagctc ttctctcagc tcttccactt     2520

catcaatatg tggctgttca atagattggt gaccgaccca gattcggggc tgtgctccca     2580

ttactggggt gcgattatcc gtcagcagtt gggccatatt gaagcctggg ctgagaagca     2640

ggggctggaa ctggctgcgg actgtcatct gagcaggatc gtgcaggcaa cgactttgct     2700

taccatggat aagtatgcac ctgatgacat tccaaatata aacagcacct gctttaagtt     2760

aaattcatta caacttcaag ccttattaca gaactatcac tgtgcacctg atgagccttt     2820

tatcccaacg gatcttatag aaaatgtagt gactgtggct gaaaacactg ccgatgagct     2880

ggcccgcagt gatggaaggg aagtgcagtt ggaggaggat cctgatctgc agctgccgtt     2940

tcttttgcca gaagatggtt attcttgtga tgttgtcaga aacattccaa atggtttaca     3000

agaattttta gaccctctgt gccagagagg attttgcagg ttaattcctc acacacgttc     3060

accaggtact tggacaatat attttgaagg tgcagattat gaaagtcacc ttctgcgtga     3120

gaacacagag ctggctcagc ctctgaggaa agaacctgaa ataatcactg tgaccctaaa     3180

aaagcagaat ggaatgggcc ttagcattgt tgcagcaaag ggtgctggtc aagataaact     3240

aggaatctat gtgaagtcgg ttgtgaaagg aggtgctgca gatgtggatg gacgtctagc     3300

tgcaggtgat cagctcctca gtgtggatgg acgaagtctg gttggactct ctcaggaaag     3360

ggcggcagaa ctcatgacaa gaacaagctc tgtggtgaca ctggaagtag caaagcaggg     3420

tgccatctac cacggtctgg ccacccttct caatcagcca tcccccatga tgcagagaat     3480

ttcagatcgt cgtggctcag gtaaaccccg accaaagagt gaaggctttg agctctataa     3540

taattcaact caaaatgggt ctcctgagag tcctcagctg ccttgggcag aatatagtga     3600

accaaagaaa ttgcctggtg atgacagact gatgaaaaat agagctgatc accgttccag     3660

ccccaacgta gcaaatcagc ctcctagtcc tggagggaaa agtgcatatg cctctggaac     3720

aacagcgaag ataacatctg tctctactgg aaacctctgc actgaggagc agacgcctcc     3780

gcctagacct gaagcctacc ccatccccac tcagacgtac accagagagt attttacctt     3840

cccagcttcc aaatcccagg atcggatggc tcctcctcag aaccagtggc caaattatga     3900

ggaaaagcca catatgcaca cagatagtaa tcattccagt attgcaattc agcgtgttac     3960

acgttcccaa gaagaacttc gagaagataa agcttaccaa cttgagcggc atcgaataga     4020

ggcagctatg gaccgaaagt ctgatagtga tatgtggata aatcagagct cctcactgga     4080

ctccagtacc tctagccagg agcatctgaa ccattcctct aagtcggtca cccctgcttc     4140

cacactgacc aaaagtggcc ctggccgttg gaaaacacca gcagccatac cggccacccc     4200

tgtggccgtc tcccagccaa tccgaacaga cctgcctccg ccacccccgc cacctccagt     4260

ccactatgcc ggtgatttcg atggaatgtc catggatttg cctctcccac cacccccttc     4320

cgccaaccag atagggctgc cgtctgcgca ggtggctgct gctgaacgga gaaagagaga     4380

agaacatcag cgttggtatg agaaggagaa ggcccgcctg gaggaggagc gggagaggaa     4440

gcggagagag caggagagga agttgggcca gatgcgcact cagtccttaa accctgctcc     4500

gttttctccc ctgactgcac agcagatgaa gcccgaaaag ccttccacac tccagcggcc     4560

acaggaaaca gtcattcggg agctgcagcc tcagcagcag ccccgcacga tcgagcgcag     4620

agacttgcag tacattacag tcagcaaaga ggagctttcc tcgggggaca gtctgtcccc     4680

cgacccgtgg aagcgggacg ccaaggagaa gctggagaag cagcagcaga tgcacatcgt     4740

ggacatgctg agcaaggaga tccaggagct ccagagcaaa ccggaccgca gcgccgagga     4800

gagcgaccgg ctgcgcaagc tcatgctgga gtggcagttc cagaagagac tccaggagtc     4860

gaagcagaag gacgaagatg acgaggagga ggaggacgat gatgtggaca ccatgctgat     4920

catgcagcgc ctggaggctg aacgaagagc gagggacgag gagcggaggc ggcagcagca     4980

gttagaagag atgcgcaagc gggaagcgga agaccgagcg aggcaagagg aagagcgccg     5040

gcggcaggag gaggagcgaa caaaacgaga cgctgaagaa aaggttatgg tcctttaagg     5100

gcagctagaa ttttaccaag ttagcctgaa cgtaatcgat tggctggggc agagcgggct     5160

ggaagttctg tgtttcttaa gaagcacgag gcagagcagg gcctggctcc cccagctttg     5220

tgattggacc tgcaacttta ccccatctgg cccacctacc tctcttctgg actgtctcca     5280

gatcccctta tctgccaagt tttgtctcct tcaaacttct gaactcttgg gcgtgtgtag     5340

cagtgagcct ctttgcaaag ggttcgtttc ctcgggcact catctttact gaacatggcc     5400

cagcttgtca ttgtgaaggt gacattggtt cagtgattgc ttaaatggca tgtggaccgt     5460

gggaagcagt aggagcgtag taagacagtt ggctgccatt caacatttca aatagatggt     5520

ttactcaaat cactcacttc tggttgatgg taaagagagc agatggctta gaaaacatga     5580

tacaggaaaa tttagtatgt aatccagtaa atatcctaag ttatttattt tcatgtgtgt     5640

gtgtgtgttt aaatcaagta acccttttaa ttgaatttta aaatgacagc gaattttgac     5700

attctgagaa atggggattt tgagatgttt ctctccatat ctccctttgt cctgtgtgtg     5760

tggccgacgc cctctggatg aagaggctgt agccgttgag ctccctgtgg gggcctgttt     5820

catcccgagg ggactgcgtg ttgctctgtg tggtttgaga gaagctgctc ttctctgtta     5880

cttcccttct atgaaggtag aagctttcag tgttacaact tctgatggcg gaaaatttag     5940

tttttattaa taattccttc ttggatagtc tagtgaacta tattaataga acagtgtact     6000

gttcacagaa aagaacttgt agggagtttt ttgtagtgat atgctctatt aggatacaga     6060

acaatctaag agtaagcttg atagacatga tgtgacttca cttaaatgga gtagagtgaa     6120

taatgtaagg acactcacct ctgttgaaat tggtgatttc tgcattttgt agacctttgc     6180

cctctaagtt tatcatcata ttatctgttg aatctgaaca gcatttgaag tcctctcaaa     6240

gagtttgagc tttcaggatt aggttcccct gtgagtcttt cacttgtgta atggtaagtc     6300

aacattgatg atctttctaa ggaaatcaga tttacaaaat gctgagccgc ttgatgtcta     6360

agtgttggtg gtttttgctg ttgctttgct gttccatgaa agcgctccct ggctgcttgg     6420

agggctgtgc ttttccaggt cagtgccagc ttggctgtcc caggccgtgc acagtgccca     6480

ttgctatagc tgggcccagt cctggccacg ccggagcctc ggcgggggca gctgggttgt     6540

cacggcagca cagtgcacat gcagagagga ccaggccatg tttttcctgt gctgagaaac     6600

tcttgggtta tttaattttt ccaatgtgtt ttcataactc atgattattt gaaatacact     6660

tgtgttagta actgcttcta taattaagtg gtcactgtaa aaaggcgaat aacctatttt     6720

tatatcagaa tgtccaaaac tcatgggttt gctttgttat agaaaaatgt gccattcatt     6780

tgttgggtag aataaagttg tcttgtaatt gtatctgctc ttggtataac taaaagagga     6840

tattttgatt tcttcctaaa atgttaccaa gcaactgttc ttcatgttaa tactaagatt     6900

cttgatagtt ccatttaaaa gccacaagaa gtcattctgg tttattcctc actccaaggg     6960

aacacttact ttgtgtagac aagaagatga gagtctttcc ttcaggattt ctaaacacag     7020

agcaagaaga ttcaatgaaa aattgggctc agggcagtaa ttggggctgg catttattct     7080

taagagtttt ctccctcaaa aggtgaagga gtgacattgc gtattcactc tgtgtgtgtg     7140

tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtagc tctagaggga gtagggagaa     7200

aatacaggat gaaattgaaa acagggacta acaacttttc actgaatgcc agcaagctct     7260

ctaaaattag ttttctttgg ttgaacaaat ttacaattca ttgtacttca tttcacagca     7320

ttaaacattt actcgaggca gtttattctg tttgctcttt catccccctt cttatttact     7380

tttttcttgt gctctaaaac ttttgtcaat ctttaacaaa actgtgctgt tacctttttt     7440

aatgttaaaa gaattttaac actgtcaact gtagtttgtg cagatgtatg tcagaaaaaa     7500

atgtacagta tgtgtcaaaa tatatttgaa tatcttgttg ctgttgctgt tagttcctgg     7560

ctctctaatt ttctgtctgt tagggagttt cttaagattt gaaatacaag ttaagaacta     7620

tggaaagca                                                             7629


<210>  81
<211>  751
<212>  DNA
<213>  homo sapiens

<400>  81
ccctgtctcc agtgggcgtc ttgggccccg gctctattct gggctgcggg cctgggaagg       60

gctcgccggg tgccaaatga gctgtcctaa ctctgcgggg ctgcagcttc ctgcatgatg      120

ctggggagct tggcgcctga cccaggatct agaaggcact ctgggcaggc cgcgctccgc      180

ccacgaaggt acccaaccct ctgggataga tgcaggaagc gatggttaag acccattttc      240

acccaacttc tcgccgcagg tctggcttac cacacgctcc tccccattcc cagtgagccg      300

ctttttgcag caccaggcga acacttacac cagtgctttg taaaggaatc ttattgtcca      360

ccccgtgtct tggcaaaaga acagtgatca cacagattcc tacttgggct ctttccttta      420

atcttcggag gctgagtttg cccaactcag gtttaaccac caaggactct gagagctggc      480

aggtctgagt aaccctggta acaattctct tcaccttatc aaaacctgag ctaaaaccaa      540

tgcatcagct gatgatgaca gcagagagtg gcagggctga ggacccaaag tcatttccca      600

ggctggcgga gaataaactg ccagggagaa gaatgagaag acaggagaca aactgtttgg      660

aaagctaaat cttccctctt aatgaataaa ggtttttgcc ttgtcttaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                                     751


<210>  82
<211>  5066
<212>  DNA
<213>  homo sapiens

<400>  82
aaagagggct ttcctccttg aaggaagggt gttgggtgaa ctaacactat tttctcctgc       60

cctttccccc aatctcaatc cctttctctc caaacattct tccttgagca ccccactctg      120

gcactcaaaa agccatggga atgggaaaga agtggctgga agtaaacagc ctgcttactc      180

acagcaactg aaaattttgt ttcgacgatt ctggttccag gggcaggagc tgaagattaa      240

tgcctggagt ctgccccatt ctgagagcag cagcctggct cctggtggct ccagcagcag      300

ccttcatatc tgtttttttc ttatgaagct tcttctggtt ggaaacttgt caaatttcat      360

cagctatgaa acccacgtag tcgaacaccg tgatgcttct cctgcagggc gtgtgatgag      420

gaggcgagct tggctttgga gtgctgggaa cctgaggaat tgccaaggac ccagagccca      480

gccctgacca ccagagtgcc caaaacacaa tgaacaaatt gaattttcat aacaacagag      540

tcatgcaaga ccgccgcagt gtgtgcattt tccttcccaa cgatgaatct ctgaacatca      600

tcataaatgt taagattctg tgtcaccagt tgctggtcca ggtttgtgac ctgctcaggc      660

taaaggactg ccacctcttt ggactcagtg ttatacaaaa taatgaacat gtgtatatgg      720

agttgtcaca aaagctttac aaatattgtc caaaagaatg gaagaaagag gccagcaagg      780

gtatcgacca atttgggcct cctatgatca tccacttccg tgtgcagtac tatgtggaaa      840

atggcagatt gatcagtgac agagcagcaa gatactatta ttactggcac ctgagaaaac      900

aagttcttca ttctcagtgt gtgctccgag aggaggccta cttcctgctg gcagcctttg      960

ccctgcaggc tgatcttggg aacttcaaaa ggaataagca ctatggaaaa tacttcgagc     1020

cagaggctta cttcccatct tgggttgttt ccaagagggg gaaggactac atcctgaagc     1080

acattccaaa catgcacaaa gatcagtttg cactaacagc ttccgaagct catcttaaat     1140

atatcaaaga ggctgtccga ctggatgacg tcgctgttca ttactacaga ttgtataagg     1200

ataaaaggga aattgaagca tcgctgactc ttggattgac catgagggga atacagattt     1260

ttcagaattt agatgaagag aaacaattac tttatgattt cccctggaca aatgttggaa     1320

aattggtgtt tgtgggtaag aaatttgaga ttttgccaga tggcttgcct tctgcccgga     1380

agctcatata ctacacgggg tgccccatgc gctccagaca cctcctgcaa cttctgagca     1440

acagccaccg cctctatatg aatctgcagc ctgtcctgcg ccatatccgg aagctggagg     1500

aaaacgaaga gaagaagcag taccgggaat cttacatcag tgacaacctg gacctcgaca     1560

tggaccagct ggaaaaacgg tcgcgggcca gcgggagcag tgcgggcagc atgaaacaca     1620

agcgcctgtc ccgtcattcc accgccagcc acagcagttc ccacacctcg ggcattgagg     1680

cagacaccaa gccccgggac acggggccag aagacagcta ctccagcagt gccatccacc     1740

gcaagctgaa aacctgcagc tcaatgacca gtcatggcag ctcccacacc tcaggggtgg     1800

agagtggcgg caaagaccgg ctggaagagg acttacagga cgatgaaata gagatgttgg     1860

ttgatgaccc ccgggatctg gagcagatga atgaagagtc tctggaagtc agcccagaca     1920

tgtgcatcta catcacagag gacatgctca tgtcgcggaa gctgaatgga cactctgggt     1980

tgattgtgaa agaaattggg tcttccacct cgagctcttc agaaacagtt gttaagcttc     2040

gtggccagag tactgattct cttccacaga ctatatgtcg gaaaccaaag acctccactg     2100

atcgacacag cttgagcctc gatgacatca gactttacca gaaagacttc ctgcgcattg     2160

caggtctgtg tcaggacact gctcagagtt acacctttgg atgtggccat gaactggatg     2220

aggaaggcct ctattgcaac agttgcttgg cccagcagtg catcaacatc caagatgctt     2280

ttccagtcaa aagaaccagc aaatactttt ctctggatct cactcatgat gaagttccag     2340

agtttgttgt gtaaagtccg tctgtgtgca gctgtacagg cagcttactg tttgctagag     2400

gatgcgaaag tcataagttc tttacatatt acttgtgcca tatcttcttc accctaaaca     2460

tagctctttc tttataatat ttgtgatgat ggaaacaaaa gccttggaac aattgcactt     2520

taagtattac acagaagtaa aagaactaca gaaaatgtac agcaagacaa gtgcccggaa     2580

gttcactgat ccttcagaag gaaatgcgct ttactgattg caaagccttc agaatattgg     2640

agtgtggtgt gtttgctcat ctgatgcttt ttagttcagt tacatgtaac atcacatttt     2700

tttatcacgt gaaagatgtt agatttgttt gcttataaat tttttaccac tcccacataa     2760

aatgctcata gtttgggaga ggaaagaggg aagattctct cttcttttaa cagagagatg     2820

attgctctgt atacccattg cttcctccct gaggctgtcc caaagtgaac actgatggag     2880

tggtcaaaat cataaggttg tagcaagcca aagatacgta tgtgacagaa gcacataagc     2940

aataagcaga aaaccagaag tgcatgctgt gatgcctgtg actccttcat cccgctcagt     3000

gccatgtcct cttttgtgat cttccagaaa gctccaggat tcatttgagt tccacatcca     3060

agtaacagat gaattatatt catgttgtaa tgcattttgt ggagtttaca aaaccagtgt     3120

ctgttaaaac tttggaaaat gtcttagaaa acgttggtgc ttggtgatgc tttatttgtt     3180

taattatcaa gaacaaatta tggcaatgct agtttctgct taaccaaaat actctgtgta     3240

tatattatac atatataaat acatgggatt gtgtatgtct atatgtgttt aaagcttact     3300

atgtcttcat tttggcttcc atgactatct tttatacatg gaattcctta agattgagaa     3360

tatgtcactg agtgaatgat acctgcagac agtcagttga tatatgtaga gttcagaatg     3420

actgttttct catgtgcctt tggccatgat tctcaacact gattgtataa cagaattttg     3480

gggggagctt ttaaaaaata atgactgagt ctcccaccag accgattaca tcattctctt     3540

gtggcgggac ccaagtagaa ttgccttttc ttttaaagtt ctccagatgg agctaatatg     3600

caacaaagtt gaaaaccact gatcctgggg gtgtcttgtt aattttgaag taaaagtgta     3660

cagaagacgt agtgtatgag aaagggccat ttttaagaca gttacctgtt gtgctgctgt     3720

tacaatatat aatgaaacca agtcagggga gtgaatttat caatcttttg atgtaaagta     3780

aaaacgtagt tcacacttca ggagagaact tcatagcaca atgtctttct ataagatatt     3840

tttaatgatt tagtatttta caacatttgt ttaccatatt ttgatatacc atttttttct     3900

atctgcccag ttttattaaa aaaactatat attattttct aaagaaacaa tcatattttt     3960

atacaaaatt atgttttcag gtaacgaaat agatgtaggg tacagtggaa cataagcagt     4020

gttacccctg gctgggagtc agtattatac aacaaatggt gagctggaac atgccctgtc     4080

tgtgctgtcc ctcctgtgct gggtcgcgga tgtgtaggca acattgcctt atcacgctag     4140

gttcacctga cactttaaaa ggaaaaaaag ttccatagag ttctgtggtc acaaaattgt     4200

tttgctttta tcaaatactt taatagaacc aaagttgcag atattggaat gtatggaagt     4260

atctcagtct ctgcataaga ggattaaagt atgaaaggat catttaatga ctgttttact     4320

tataagtcat taagtaatcc accatttctt atggatgatg cttaagcctg gtgaggtttg     4380

tactctaagg agcccagatc ataatgcagt gcatttcctt agcccttaga gtttcttgca     4440

aacatttaaa aaaagacata tttaagaaag aaagataaag aaaaaacata tttaattact     4500

gtaaacaggt actgctttat gtttattttc tctctacttc aaccaaaatc agatctttga     4560

ggttttgctg acattgttgg tggttttgca catgttcttt ctaattggat ttatgaatag     4620

ttctatgggt tttcaaagat gaatcatgct aagaacactt ctgctttttg atccactgtt     4680

tgcagcagaa ttatatatat gtataggaaa aatccacttt gaataatcca tgttttgtat     4740

ttggaaattg tttttaaaaa taaaaaggaa aggaaatata taaagctgtt atttattctg     4800

catttcttac atatctatcg cttgtcagta tacccgtttt ggtatatatt gcctctgcac     4860

atctacattt gtatatgcaa cagtgagctt tatatctaca taaactgtaa ataatccttt     4920

ctgtgaaagg atcatcatat caagatgata ccaaaagtat gtaaaaagaa acctgcatta     4980

ttttgtaatt atttcttata gatatttcat ggtaagatta gcagtcaata aagttacttt     5040

tttgccttta aaaaaaaaaa aaaaaa                                          5066


<210>  83
<211>  4842
<212>  DNA
<213>  homo sapiens

<400>  83
ggggcggggc ggacgcggag cgcccctctg gctggcgggg ccaaggggct gagaggagtg       60

gggcaggctc ggcgccggta ggaagagtca gaggggtgac cagagagccc aacgcctggt      120

gctcaagact ttctccgagc tatgaaaccc acgtagtcga acaccgtgat gcttctcctg      180

cagggcgtgt gatgaggagg cgagcttggc tttggagtgc tgggaacctg aggaattgcc      240

aaggacccag agcccagccc tgaccaccag agtgcccaaa acacaatgaa caaattgaat      300

tttcataaca acagagtcat gcaagaccgc cgcagtgtgt gcattttcct tcccaacgat      360

gaatctctga acatcatcat aaatgttaag attctgtgtc accagttgct ggtccaggtt      420

tgtgacctgc tcaggctaaa ggactgccac ctctttggac tcagtgttat acaaaataat      480

gaacatgtgt atatggagtt gtcacaaaag ctttacaaat attgtccaaa agaatggaag      540

aaagaggcca gcaagggtat cgaccaattt gggcctccta tgatcatcca cttccgtgtg      600

cagtactatg tggaaaatgg cagattgatc agtgacagag cagcaagata ctattattac      660

tggcacctga gaaaacaagt tcttcattct cagtgtgtgc tccgagagga ggcctacttc      720

ctgctggcag cctttgccct gcaggctgat cttgggaact tcaaaaggaa taagcactat      780

ggaaaatact tcgagccaga ggcttacttc ccatcttggg ttgtttccaa gagggggaag      840

gactacatcc tgaagcacat tccaaacatg cacaaagatc agtttgcact aacagcttcc      900

gaagctcatc ttaaatatat caaagaggct gtccgactgg atgacgtcgc tgttcattac      960

tacagattgt ataaggataa aagggaaatt gaagcatcgc tgactcttgg attgaccatg     1020

aggggaatac agatttttca gaatttagat gaagagaaac aattacttta tgatttcccc     1080

tggacaaatg ttggaaaatt ggtgtttgtg ggtaagaaat ttgagatttt gccagatggc     1140

ttgccttctg cccggaagct catatactac acggggtgcc ccatgcgctc cagacacctc     1200

ctgcaacttc tgagcaacag ccaccgcctc tatatgaatc tgcagcctgt cctgcgccat     1260

atccggaagc tggaggaaaa cgaagagaag aagcagtacc gggaatctta catcagtgac     1320

aacctggacc tcgacatgga ccagctggaa aaacggtcgc gggccagcgg gagcagtgcg     1380

ggcagcatga aacacaagcg cctgtcccgt cattccaccg ccagccacag cagttcccac     1440

acctcgggca ttgaggcaga caccaagccc cgggacacgg ggccagaaga cagctactcc     1500

agcagtgcca tccaccgcaa gctgaaaacc tgcagctcaa tgaccagtca tggcagctcc     1560

cacacctcag gggtggagag tggcggcaaa gaccggctgg aagaggactt acaggacgat     1620

gaaatagaga tgttggttga tgacccccgg gatctggagc agatgaatga agagtctctg     1680

gaagtcagcc cagacatgtg catctacatc acagaggaca tgctcatgtc gcggaagctg     1740

aatggacact ctgggttgat tgtgaaagaa attgggtctt ccacctcgag ctcttcagaa     1800

acagttgtta agcttcgtgg ccagagtact gattctcttc cacagactat atgtcggaaa     1860

ccaaagacct ccactgatcg acacagcttg agcctcgatg acatcagact ttaccagaaa     1920

gacttcctgc gcattgcagg tctgtgtcag gacactgctc agagttacac ctttggatgt     1980

ggccatgaac tggatgagga aggcctctat tgcaacagtt gcttggccca gcagtgcatc     2040

aacatccaag atgcttttcc agtcaaaaga accagcaaat acttttctct ggatctcact     2100

catgatgaag ttccagagtt tgttgtgtaa agtccgtctg tgtgcagctg tacaggcagc     2160

ttactgtttg ctagaggatg cgaaagtcat aagttcttta catattactt gtgccatatc     2220

ttcttcaccc taaacatagc tctttcttta taatatttgt gatgatggaa acaaaagcct     2280

tggaacaatt gcactttaag tattacacag aagtaaaaga actacagaaa atgtacagca     2340

agacaagtgc ccggaagttc actgatcctt cagaaggaaa tgcgctttac tgattgcaaa     2400

gccttcagaa tattggagtg tggtgtgttt gctcatctga tgctttttag ttcagttaca     2460

tgtaacatca cattttttta tcacgtgaaa gatgttagat ttgtttgctt ataaattttt     2520

taccactccc acataaaatg ctcatagttt gggagaggaa agagggaaga ttctctcttc     2580

ttttaacaga gagatgattg ctctgtatac ccattgcttc ctccctgagg ctgtcccaaa     2640

gtgaacactg atggagtggt caaaatcata aggttgtagc aagccaaaga tacgtatgtg     2700

acagaagcac ataagcaata agcagaaaac cagaagtgca tgctgtgatg cctgtgactc     2760

cttcatcccg ctcagtgcca tgtcctcttt tgtgatcttc cagaaagctc caggattcat     2820

ttgagttcca catccaagta acagatgaat tatattcatg ttgtaatgca ttttgtggag     2880

tttacaaaac cagtgtctgt taaaactttg gaaaatgtct tagaaaacgt tggtgcttgg     2940

tgatgcttta tttgtttaat tatcaagaac aaattatggc aatgctagtt tctgcttaac     3000

caaaatactc tgtgtatata ttatacatat ataaatacat gggattgtgt atgtctatat     3060

gtgtttaaag cttactatgt cttcattttg gcttccatga ctatctttta tacatggaat     3120

tccttaagat tgagaatatg tcactgagtg aatgatacct gcagacagtc agttgatata     3180

tgtagagttc agaatgactg ttttctcatg tgcctttggc catgattctc aacactgatt     3240

gtataacaga attttggggg gagcttttaa aaaataatga ctgagtctcc caccagaccg     3300

attacatcat tctcttgtgg cgggacccaa gtagaattgc cttttctttt aaagttctcc     3360

agatggagct aatatgcaac aaagttgaaa accactgatc ctgggggtgt cttgttaatt     3420

ttgaagtaaa agtgtacaga agacgtagtg tatgagaaag ggccattttt aagacagtta     3480

cctgttgtgc tgctgttaca atatataatg aaaccaagtc aggggagtga atttatcaat     3540

cttttgatgt aaagtaaaaa cgtagttcac acttcaggag agaacttcat agcacaatgt     3600

ctttctataa gatattttta atgatttagt attttacaac atttgtttac catattttga     3660

tataccattt ttttctatct gcccagtttt attaaaaaaa ctatatatta ttttctaaag     3720

aaacaatcat atttttatac aaaattatgt tttcaggtaa cgaaatagat gtagggtaca     3780

gtggaacata agcagtgtta cccctggctg ggagtcagta ttatacaaca aatggtgagc     3840

tggaacatgc cctgtctgtg ctgtccctcc tgtgctgggt cgcggatgtg taggcaacat     3900

tgccttatca cgctaggttc acctgacact ttaaaaggaa aaaaagttcc atagagttct     3960

gtggtcacaa aattgttttg cttttatcaa atactttaat agaaccaaag ttgcagatat     4020

tggaatgtat ggaagtatct cagtctctgc ataagaggat taaagtatga aaggatcatt     4080

taatgactgt tttacttata agtcattaag taatccacca tttcttatgg atgatgctta     4140

agcctggtga ggtttgtact ctaaggagcc cagatcataa tgcagtgcat ttccttagcc     4200

cttagagttt cttgcaaaca tttaaaaaaa gacatattta agaaagaaag ataaagaaaa     4260

aacatattta attactgtaa acaggtactg ctttatgttt attttctctc tacttcaacc     4320

aaaatcagat ctttgaggtt ttgctgacat tgttggtggt tttgcacatg ttctttctaa     4380

ttggatttat gaatagttct atgggttttc aaagatgaat catgctaaga acacttctgc     4440

tttttgatcc actgtttgca gcagaattat atatatgtat aggaaaaatc cactttgaat     4500

aatccatgtt ttgtatttgg aaattgtttt taaaaataaa aaggaaagga aatatataaa     4560

gctgttattt attctgcatt tcttacatat ctatcgcttg tcagtatacc cgttttggta     4620

tatattgcct ctgcacatct acatttgtat atgcaacagt gagctttata tctacataaa     4680

ctgtaaataa tcctttctgt gaaaggatca tcatatcaag atgataccaa aagtatgtaa     4740

aaagaaacct gcattatttt gtaattattt cttatagata tttcatggta agattagcag     4800

tcaataaagt tacttttttg cctttaaaaa aaaaaaaaaa aa                        4842


<210>  84
<211>  4621
<212>  DNA
<213>  homo sapiens

<400>  84
gctcagaaac tgccagccca gaccacaggc tcagaggctg aagcaggagg aaggaaggac       60

tggaaggaaa aagagacagg ttagagggaa agaggcttgg gaagaaaaca gcagaaaaga      120

aactgctcat tacacttaca gagaggcaag taacggtgga gatgaggaca gagggaacca      180

agactctgaa agacaaaaaa tacaaataga gcgaaagagg aaaaaaatgt caagaagaac      240

atccatccgg agaaatgaag agaatgaaag ttttaagctg cagagccgtt ctgtgctttt      300

ccggcacaaa attatatcgc tgattttaag cccttttgca tttgccagcc gttgacatta      360

agaggcatgt ttaacggtgc caacagcatc tccttttcct tctcctcttc ctcttcttct      420

tcttcctcct cctcctcctc tttttcctcc tcctcgttct cctcccatca gcaagaagac      480

aaaccgagga cagtcttgaa atatcgaaat ttcctctttg ggatttgcca gcgccaagac      540

tgtcggaata aaggacgctg actattgtat tattgttatt ttattaatta gtcagtggaa      600

agattacaga tgaggaaagg ggacgcctgt cacccttcct gtgctaagat ttaaaaaaaa      660

atgaggctgg attgcgggaa gctctaaaat gaagcaaaag gagtaagatt tttaaagaca      720

gaaagccaca ggagccccca cgtagcgcac ttttatttgt attttttcag attttttttt      780

gtttcgtggt ggtgggggag gtgattgggt ggctgactgg ctgcgggaag ctacttcctt      840

tccttttgga gatgattgtg ctattattgt ttgccttgct ctggatggtg gaaggagtct      900

tttcccagct tcactacacg gtacaggagg agcaggaaca tggcactttc gtggggaata      960

tcgctgaaga tctgggtctg gacattacaa aactttcggc tcgcgggttt cagacggtgc     1020

ccaactcaag gaccccttac ttagacctca acctggagac aggggtgctg tacgtgaacg     1080

agaaaataga ccgcgaacaa atctgcaaac agagcccctc ctgtgtcctg cacctggagg     1140

tctttctgga gaaccccctg gagctgttcc aggtggagat cgaggtgctg gacattaatg     1200

acaacccccc ctctttcccg gagccagacc tgacggtgga aatctctgag agcgccacgc     1260

caggcactcg cttccccttg gagagcgcat tcgacccaga cgtgggcacc aactccttgc     1320

gcgactacga gatcaccccc aacagctact tctccctgga cgtgcagacc cagggggatg     1380

gcaaccgatt cgctgagctg gtgctggaga agccactgga ccgagagcag caagcggtgc     1440

accgctacgt gctgaccgcg gtggacggag gaggtggggg aggagtagga gaaggagggg     1500

gaggtggcgg gggagcaggc ctgccccccc agcagcagcg caccggcacg gccctactca     1560

ccatccgagt gctggactcc aatgacaatg tgcccgcttt cgaccaaccc gtctacactg     1620

tgtccctacc agagaactct cccccaggca ctctcgtgat ccagctcaac gccaccgacc     1680

cggacgaggg ccagaacggt gaggtcgtgt actccttcag cagccacatt tcgccccggg     1740

cgcgggagct tttcggactc tcgccgcgca ctggcagact ggaggtaagc ggcgagttgg     1800

actatgaaga gagcccagtg taccaagtgt acgtgcaagc caaggacctg ggccccaacg     1860

ccgtgcctgc gcactgcaag gtgctagtgc gagtactgga tgctaatgac aacgcgccag     1920

agatcagctt cagcaccgtg aaggaagcgg tgagtgaggg cgcggcgccc ggcactgtgg     1980

tggccctttt cagcgtgact gaccgcgact cagaggagaa tgggcaggtg cagtgcgagc     2040

tactgggaga cgtgcctttc cgcctcaagt cttcctttaa gaattactac accatcgtta     2100

ccgaagcccc cctggaccga gaggcggggg actcctacac cctgactgta gtggctcggg     2160

accggggcga gcctgcgctc tccaccagta agtcgatcca ggtacaagtg tcggatgtga     2220

acgacaacgc gccgcgtttc agccagccgg tctacgacgt gtatgtgact gaaaacaacg     2280

tgcctggcgc ctacatctac gcggtgagcg ccaccgaccg ggatgagggc gccaacgccc     2340

agcttgccta ctctatcctc gagtgccaga tccagggcat gagcgtcttc acctacgttt     2400

ctatcaactc tgagaacggc tacttgtacg ccctgcgctc cttcgactat gagcagctga     2460

aggacttcag ttttcaggtg gaagcccggg acgctggcag cccccaggcg ctggctggta     2520

acgccactgt caacatcctc atagtggatc aaaatgacaa cgcccctgcc atcgtggcgc     2580

ctctaccagg gcgcaacggg actccagcgc gtgaggtgct gccccgctcg gcggagccgg     2640

gttacctgct cacccgcgtg gccgccgtgg acgcggacga cggcgagaac gcccggctca     2700

cttacagcat cgtgcgtggc aacgaaatga acctctttcg catggactgg cgcaccgggg     2760

agctgcgcac agcacgccga gtcccggcca agcgcgaccc ccagcggcct tatgagctgg     2820

tgatcgaggt gcgcgaccat gggcagccgc ccctttcctc caccgccacc ctggtggttc     2880

agctggtgga tggcgccgtg gagccccagg gcgggggcgg gagcggaggc ggagggtcag     2940

gagagcacca gcgccccagt cgctctggcg gcggggaaac ctcgctagac ctcaccctca     3000

tcctcatcat cgcgttgggc tcggtgtcct tcatcttcct gctggccatg atcgtgctgg     3060

ccgtgcgttg ccaaaaagag aagaagctca acatctatac ttgtctggcc agcgattgct     3120

gcctctgctg ctgctgctgc ggtggcggag gttcgacctg ctgtggccgc caagcccggg     3180

cgcgcaagaa gaaactcagc aagtcagaca tcatgctggt gcagagctcc aatgtaccca     3240

gtaacccggc ccaggtgccg atagaggagt ccgggggctt tggctcccac caccacaacc     3300

agaattactg ctatcaggta tgcctgaccc ctgagtccgc caagaccgac ctgatgtttc     3360

ttaagccctg cagcccttcg cggagtacgg acactgagca caacccctgc ggggccatcg     3420

tcaccggtta caccgaccag cagcctgata tcatctccaa cggaagcatt ttgtccaacg     3480

aggtaaggct gaagcgaaag gaccaccatc tctcatctcc tccatcagaa agcctcctct     3540

agcccggccc ttgtatctct ggtgcactgt atctattttt aggatattag cttatgtgta     3600

tcgttgtggg agcagagatg ggcggtcacc ttctcccact ccttcgtgtg taacctaact     3660

ttcgcgttgt tccacccttt cacatttatt ttcattccgt ccccttggta ctttgccacc     3720

ttggagctcc ctcctttgct cttccatcct gtcagtcctt tcccttctca gtaacctggg     3780

catgaaggga aactgcgtga agggagaggg aaatgtggag gagggactta ctttctagca     3840

ctggcaaagg tcttttttct ttgcgtctgt cccaggcatt aataaagttg gctctatttt     3900

gctttgttta acgatgcttt tagtcgcgtg tacaagtaag ctatagattg tttaacttta     3960

cacagttgtc taacctcgaa ttcatgtttt agtgaacaag ttaccagatc cttctcctct     4020

gaactcgggt tgcaaaaaaa gccttcagtt cggctctgga cagcatttac agacgctctt     4080

gaagccgagc gcccacacag tgtgaatttg aatgaagctg cgttggcaca aacccctgtt     4140

aagagtaaac taacgaaagg cttaaacaat tgttgtctta aatatatctt tttagctaat     4200

aatcaccttc ttgccactgt tttggataaa tcacgctgtt ggctttcttc ataaaagaat     4260

ttggcttgtc aattctgact tctttttaaa aggatggaga agtgacaaag tcggagggtg     4320

ggggttgggg ggagaacaaa gttggtttat gtgaaagaaa gcttggaccg gaaaggtgtg     4380

tgggtggtag aggtggggag gcgaatgcag agggcctttg gaggggaaaa gaatgggggt     4440

ggtggggggc gggcaggatt atgaactcct ttcctggcag gttattttat ttgagtctta     4500

gatattatta attgactttc atgaatattt gtacagctca tttgtatctt aagcacattt     4560

tgaaaataaa caacaacata attccaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     4620

a                                                                     4621


<210>  85
<211>  5336
<212>  DNA
<213>  homo sapiens

<400>  85
gctgctccgc gcgcagccgg ctcgggccgc tcctcctgac tgaggcgcgg cggcggcggt       60

ggctgtgacc gcgcggaccg agccgagaca ttcgcgccgg gggatcgggc gccgccgccg      120

ctgggccccg ggcgcgtgga tgcggctggg tcgggcggcg ccgtacacct gaggcggaga      180

acggggcgcg gcgcgggtga cgctgtcagg gccgcggttc ctgacgccca ggcgctcgcc      240

aggacgagcc aggcagtgat ttgaggcacc ggcttcacct tcacccatgg tccggagagc      300

ctagcggggc tcgccaccgc ctcccggctc cccttccacg cctcatcctg ccagcctcgc      360

cgccccgcca gcgccgggca accgcctcgc ccgaagccct ccctcgttac tgtccgcata      420

ccccggcggc gccgccgcgg gaagcggctc cccctcctct tcctccgcgt cctcttccct      480

ctttcccccg ccggggccgc ttgttgcacc gccccgcggc ctgcgggagc cgctcgcccc      540

ggccttgtgc tcgcgtccgc acccctttcc tgtcgccccc cggggcccgc accacagccc      600

ggccggcgag accccggcca gaccccgctg cccgcacaaa atgtcggccc ggacgccatt      660

gccgacggtg aacgagcggg acacggaaaa tcatacatct gtggatggat atactgaacc      720

acacatccag cctaccaagt cgagtagcag acagaacatc ccccggtgta gaaactccat      780

tacgtcagca acagatgaac agcctcacat tggaaattac cgtttacaaa aaacaatagg      840

gaagggaaat tttgccaaag tcaaattggc aagacacgtt ctaactggta gagaggttgc      900

tgtgaaaata atagacaaaa ctcagctaaa tcctaccagt ctacaaaagt tatttcgaga      960

agtacgaata atgaagatac tgaatcatcc taatatagta aaattgtttg aagttattga     1020

aacagagaag actctctatt tagtcatgga atacgcgagt gggggtgaag tatttgatta     1080

cttagttgcc catggaagaa tgaaagagaa agaggcccgt gcaaaattta ggcagattgt     1140

atctgctgta cagtattgtc atcaaaagta cattgttcac cgtgatctta aggctgaaaa     1200

ccttctcctt gatggtgata tgaatattaa aattgctgac tttggtttta gtaatgaatt     1260

tacagttggg aacaaattgg acacattttg tggaagccca ccctatgctg ctcccgagct     1320

tttccaagga aagaagtatg atgggcctga agtggatgtg tggagtctgg gcgtcattct     1380

ctatacatta gtcagtggct ccttgccttt cgatggccag aatttaaagg aactgcgaga     1440

gcgagtttta cgagggaagt accgtattcc cttctatatg tccacagact gtgaaaatct     1500

tctgaagaaa ttattagtcc tgaatccaat aaagagaggc agcttggaac aaataatgaa     1560

agatcgatgg atgaatgttg gtcatgaaga ggaagaacta aagccatata ctgagcctga     1620

tccggatttc aatgacacaa aaagaataga cattatggtc accatgggct ttgcacgaga     1680

tgaaataaat gatgccttaa taaatcagaa gtatgatgaa gttatggcta cttatattct     1740

tctaggtaga aaaccacctg aatttgaagg tggtgaatcg ttatccagtg gaaacttgtg     1800

tcagaggtcc cggcccagta gtgacttaaa caacagcact cttcagtccc ctgctcacct     1860

gaaggtccag agaagtatct cagcaaatca gaagcagcgg cgtttcagtg atcatgctgg     1920

tccatccatt cctcctgctg tatcatatac caaaagacct caggctaaca gtgtggaaag     1980

tgaacagaaa gaggagtggg acaaagatgt ggctcgaaaa cttggcagca caacagttgg     2040

atcaaaaagc gagatgactg caagccctct tgtagggcca gagaggaaaa aatcttcaac     2100

tattccaagt aacaatgtgt attctggagg tagcatggca agaaggaata catatgtctg     2160

tgaaaggacc acagatcgat acgtagcatt gcagaatgga aaagacagca gccttacgga     2220

gatgtctgtg agtagcatat cttctgcagg ctcttctgtg gcctctgctg tcccctcagc     2280

acgaccccgc caccagaagt ccatgtccac ttctggtcat cctattaaag tcacactgcc     2340

aaccattaaa gacggctctg aagcttaccg gcctggtaca acccagagag tgcctgctgc     2400

ttccccatct gctcacagta ttagtactgc gactccagac cggacccgtt ttccccgagg     2460

gagctcaagc cgaagcactt tccatggtga acagctccgg gagcgacgca gcgttgctta     2520

taatgggcca cctgcttcac catcccatga aacgggtgca tttgcacatg ccagaagggg     2580

aacgtcaact ggtataataa gcaaaatcac atccaaattt gttcgcaggg atccaagtga     2640

aggcgaagcc agtggcagaa ccgacacctc aagaagtaca tcaggggaac caaaagaaag     2700

agacaaggaa gagggtaaag attctaagcc gcgttctttg cggttcacat ggagtatgaa     2760

gaccactagt tcaatggacc ctaatgacat gatgagagaa atccgaaaag tgttagatgc     2820

aaataactgt gattatgagc aaaaagagag atttttgctt ttctgtgtcc atggagacgc     2880

tagacaggat agcctcgtgc agtgggagat ggaagtctgc aagttgccac gactgtcact     2940

taatggggtt cgcttcaagc gaatatctgg gacatctatt gcctttaaga acattgcatc     3000

aaaaatagca aatgagctta agctgtaaag aagtccaaat ttacaggttc agggaagata     3060

catacatata tgaggtacag tttttgaatg tactggtaat gcctaatgtg gtctgcctgt     3120

gaatctcccc atgtagaatt tgcccttaat gcaataaggt tatacatagt tatgaactgt     3180

aaaattaaag tcagtatgaa ctataataaa tatctgtagc ttaaaaagta ggttcacatg     3240

tacaggtaag tatattgtgt atttctgttc attttctgtt catagagttg tataataaaa     3300

catgattgct taaaaacttg tatagttgtc tagatttctg cacctgaatg tatgtttgat     3360

gctttgattt gaaaatgttc ttccctgtta tttacattct ggtgggtttt taaaattctt     3420

acctccatca tgcaattttg aaaattgtgt ccagaattaa aagtgcatag aaatagcctt     3480

tacaattgta gcatggacct ttaaaaattg ttttaaaatc ttatttaaat ttaaaccaga     3540

agctgaaaaa tagatcagct ttattataca caaaattatt actgcttatc tttgctcttt     3600

tccttgttat cccgcaaggt ttagttgaga agatacaaaa tgtttacagt gttggcactt     3660

agagttttta aattcaagta catgaaattc agtaatagca ttgccttgag ctaactagga     3720

agtaccggga aaaaagttaa atctacatca agtttctttt gaactttgaa gtgttttctg     3780

acccactgct aactgtagca acaaaattta aaagaaaaaa aacatacttt atctggctat     3840

tataacataa actgtcacgt aggtttgctg ccttcagaat accgcaattt aattgcggga     3900

atataataat attgggactg tttcacagca caaactcatc tttacagtgt tgatcaatgc     3960

atcagttaag aaataatgcc acctcaggaa ttaactggca ttgggaacat ttgcctcatt     4020

ctcctgctat cctcttcatt cacccctgcc actgtaatat ctataagtac ttaagagact     4080

tgtgagcaaa acatactatt tataacagta tatgattgat ttatgcttat gtggttgttc     4140

agtttgttcc catgtaactc gtttgtttta aatattttgc cagatttctt gtatttattc     4200

cacatcatta tgcctataat gtgccgcttt gtgattgggc atttgcctac ttttctttca     4260

taattagtga tatatgcgat gtaaaaccac tagtaaaggt acattttaat acttgttatt     4320

ttatactgaa ttagccttgg aggttgactg tgcaatgtta tttactgttg taattactgt     4380

aataccaaca tatgggcccc atctgcacac tcctgaaaaa cagaaagtgt attcaaattt     4440

tatcagttta aagaaaataa agctgtgata aatactgtaa ttccaaccta cattagaagg     4500

tctaagtgta ggtgatgtgc cattccataa tggcttccag actagggtga attttatgtt     4560

ctgtactgta ctgtgatgta gctttcttct gtaacagtta tgttttaaaa ttaagtgagt     4620

tttttttttg ccttagcaaa gggtggtgtt tgaaaaaaaa aatgtgtagc ccctttttaa     4680

cctagtgttc attcaaaaaa aaattgatgc aaatctttat tcactttcac tggtgcacac     4740

tgaaatttta cttgaacagt tctcataata aagcacttgt cttttgctct ttatcagaat     4800

gtgaattacc tgttttctgg tacaaaagta ttctgtatga ggagtttatt gtatgtgttc     4860

taaatttagt tggcaaaggg tgaagctgtg aaggttttca agattattga aactatgaag     4920

gtttcttgtc attatgacaa gaaagtttaa tctttttata ggaattcctg tcactgaaat     4980

acgtttttaa aaaaatagac tcatgtgttt tccacggtag aaactgatat ttttttacat     5040

tttctcactg tggccaactc ttctgtgttt gtagaaagga atttgacttc aatatctttt     5100

atgaactaaa aatgaaatct tgatactcac tttagatttt tcattttatg tgttcatgac     5160

aacataaata tttttcaaag atttagagga attttgcaat gtgtttgcat aaataaatac     5220

cagtttatgt tcaccggcta tgtgatacca ggatttcctt ggcttctgtt gaaatattat     5280

ttgatatgac atcccttata ttaaattaat tattttgtaa aaaaaaaaaa aaaaaa         5336


<210>  86
<211>  1901
<212>  DNA
<213>  homo sapiens

<400>  86
cgcacttctg actcgagtcc ccgccgcgct tgtcgtcgcc gccgccggga tccgcagccc       60

cgcgccatgg agccggccgc gggcatccag cgccgcagct cccaggggcc caccgtcccg      120

ccgccgcccc ggggccacgc gccaccggct gccgcccccg gcccggcccc gctgagctcc      180

ccggtgcgcg agccgcccca gctggaggag gagcggcagg tgcggatcag cgagagcggc      240

cagttcagcg acgggctgga ggaccgaggc ttactagaaa gcagcacccg cctgaaacct      300

cacgaagccc agaactacag gaagaaggca ttgtgggtgt cctggttctc catcattgtc      360

accctggccc tcgcggtggc tgcctttact gtctccgtta tgaggtacag cgcctctgct      420

tttgggtttg catttgatgc catcctggac gtcctgtcat cggcgattgt cctgtggcgt      480

tacagcaacg cggccgctgt gcactctgcc catagggagt acatagcctg tgtcatcttg      540

ggggtgatat tccttctgtc atccatatgt atagtggtca aagccatcca tgacctctca      600

actaggctgc tcccagaagt ggacgatttc ctgttcagtg tctccatttt aagtgggatt      660

ctttgcagca tcctggccgt gttgaagttc atgctgggga aggttctgac cagtagagca      720

ctcataacag atgggtttaa ctccctcgtg ggtggcgtga tgggcttctc cattcttctg      780

agcgcggaag tgttcaagca tgactcggcg gtctggtacc tggacggcag cataggcgtt      840

ctgatcggcc tcaccatatt tgcctatggg gtcaaactcc tcatcgacat ggtgccgagg      900

gtgaggcaga cacgtcacta cgagatgttt gagtgaaggg ggccagcatc cgcatgagac      960

catcgagatg aggagtttcc acataggcaa agggtgccaa tatttaactg aacatctggt     1020

ttctttttgg aagttttctt tcacatggtt tgtcattaca agacaaggtc tgcccagcca     1080

ggtggatcta ccttgccccc atcacctgcc gcccccatca aacatgttgg gacaatgccc     1140

ataggaatgg acctccttcc ccgtctccag ctgggactgg cgttttttag tctctggagt     1200

atgatggttc tcatgggtag gatgagatct ttggcagaaa ggtcttcggt ggtgctctga     1260

gcctgcgctg cataggactg agcagaccca cctcctccag cttgggtggc cctgccactc     1320

ctggttccaa gtctctcctt tcctggcagg tcttaaggga agattgtacc cctcaccctt     1380

tacataccca gaatcatcag tatgtcactt cctaatttct atcagtgtat ctcattattt     1440

catactgttt tactaatcct aagtctaaac agatttgctc aaaaggagac cattctattt     1500

tttaaagtac ttagtgatac acgtataagc tttgcatgga cgaattaaat aagcacattg     1560

accttttctt gtacattcag aacctgaaca tccatgtgaa aactgggtcc atttttgaga     1620

gatgtgaaac tacagtttat ttgtaataaa taaatataat ctatccgtat atgcatatat     1680

ctatatgctg tgttaagtgg taatgggtac attacagtct gtgagagatg gatcgctccc     1740

tctgtaagga acaagacgtt ctcagctgat gtcacggtag gtttagattc tgtagagtgt     1800

tccccaaccc gcaccgttct gtacctctca caccactgct tgcccgggca gtagtggctg     1860

accaataaag acctttacct gttttgtatg gcaaaaaaaa a                         1901


<210>  87
<211>  8422
<212>  DNA
<213>  homo sapiens

<400>  87
gcgcgcagtg agaggcgccg gggctgccgc ccggtgctcg gcgcgctctc gggagccgcc       60

cgcccgctgg tcccgcagcc ttccgggagg aagcggtgcc ggcagcgtcc agggcgcgct      120

ctcgggcacc ctcacctgcc ggcgcccggc cgcttacccg gcagggcgtg cgcagggtag      180

ggtgcgggac cggggggacc tggaggcaga ggggagaacc ggccgtccgc gccgcagcac      240

agccgctggg agcgcctcag accccgcgcg gggcgccggc tccatggcga ccgggctcgg      300

ggagccggtc tatggacttt ccgaagacga gggagagtcc cgtattctca gagtaaaagt      360

tgtttctgga attgatctcg ccaaaaagga catctttgga gccagtgatc cgtatgtgaa      420

actttcattg tacgtagcgg atgagaatag agaacttgct ttggtccaga caaaaacaat      480

taaaaagaca ctgaacccaa aatggaatga agaattttat ttcagggtaa acccatctaa      540

tcacagactc ctatttgaag tatttgacga aaatagactg acacgagacg acttcctggg      600

ccaggtggac gtgcccctta gtcaccttcc gacagaagat ccaaccatgg agcgacccta      660

tacatttaag gactttctcc tcagaccaag aagtcataag tctcgagtta agggattttt      720

gcgattgaaa atggcctata tgccaaaaaa tggaggtcaa gatgaagaaa acagtgacca      780

gagggatgac atggagcatg gatgggaagt tgttgactca aatgactcgg cttctcagca      840

ccaagaggaa cttcctcctc ctcctctgcc tcccgggtgg gaagaaaaag tggacaattt      900

aggccgaact tactatgtca accacaacaa ccggaccact cagtggcaca gaccaagcct      960

gatggacgtg tcctcggagt cggacaataa catcagacag atcaaccagg aggcagcaca     1020

ccggcgcttc cgctcccgca ggcacatcag cgaagacttg gagcccgagc cctcggaggg     1080

cggggatgtc cccgagcctt gggagaccat ttcagaggaa gtgaatatcg ctggagactc     1140

tctcggtctg gctctgcccc caccaccggc ctccccagga tctcggacca gccctcagga     1200

gctgtcagag gaactaagca gaaggcttca gatcactcca gactccaatg gggaacagtt     1260

cagctctttg attcaaagag aaccctcctc aaggttgagg tcatgcagtg tcaccgacgc     1320

agttgcagaa cagggccatc taccaccgcc atcagtggcc tatgtacata ccacgccggg     1380

tctgccttca ggctgggaag aaagaaaaga tgctaagggg cgcacatact atgtcaatca     1440

taacaatcga accacaactt ggactcgacc tatcatgcag cttgcagaag atggtgcgtc     1500

cggatcagcc acaaacagta acaaccatct aatcgagcct cagatccgcc ggcctcgtag     1560

cctcagctcg ccaacagtaa ctttatctgc cccgctggag ggtgccaagg actcacccgt     1620

acgtcgggct gtgaaagaca ccctttccaa cccacagtcc ccacagccat caccttacaa     1680

ctcccccaaa ccacaacaca aagtcacaca gagcttcttg ccacccggct gggaaatgag     1740

gatagcgcca aacggccggc ccttcttcat tgatcataac acaaagacta caacctggga     1800

agatccacgt ttgaaatttc cagtacatat gcggtcaaag acatctttaa accccaatga     1860

ccttggcccc cttcctcctg gctgggaaga aagaattcac ttggatggcc gaacgtttta     1920

tattgatcat aatagcaaaa ttactcagtg ggaagaccca agactgcaga acccagctat     1980

tactggtccg gctgtccctt actccagaga atttaagcag aaatatgact acttcaggaa     2040

gaaattaaag aaacctgctg atatccccaa taggtttgaa atgaaacttc acagaaataa     2100

catatttgaa gagtcctatc ggagaattat gtccgtgaaa agaccagatg tcctaaaagc     2160

tagactgtgg attgagtttg aatcagagaa aggtcttgac tatgggggtg tggccagaga     2220

atggttcttc ttactgtcca aagagatgtt caacccctac tacggcctct ttgagtactc     2280

tgccacggac aactacaccc ttcagatcaa ccctaattca ggcctctgta atgaggatca     2340

tttgtcctac ttcactttta ttggaagagt tgctggtctg gccgtatttc atgggaagct     2400

cttagatggt ttcttcatta gaccatttta caagatgatg ttgggaaagc agataaccct     2460

gaatgacatg gaatctgtgg atagtgaata ttacaactct ttgaaatgga tcctggagaa     2520

tgaccctact gagctggacc tcatgttctg catagacgaa gaaaactttg gacagacata     2580

tcaagtggat ttgaagccca atgggtcaga aataatggtc acaaatgaaa acaaaaggga     2640

atatatcgac ttagtcatcc agtggagatt tgtgaacagg gtccagaagc agatgaacgc     2700

cttcttggag ggattcacag aactacttcc tattgatttg attaaaattt ttgatgaaaa     2760

tgagctggag ttgctcatgt gcggcctcgg tgatgtggat gtgaatgact ggagacagca     2820

ttctatttac aagaacggct actgcccaaa ccaccccgtc attcagtggt tctggaaggc     2880

tgtgctactc atggacgccg aaaagcgtat ccggttactg cagtttgtca cagggacatc     2940

gcgagtacct atgaatggat ttgccgaact ttatggttcc aatggtcctc agctgtttac     3000

aatagagcaa tggggcagtc ctgagaaact gcccagagct cacacatgct ttaatcgcct     3060

tgacttacct ccatatgaaa cctttgaaga tttacgagag aaacttctca tggccgtgga     3120

aaatgctcaa ggatttgaag gggtggatta agcaccctgt gcctcggggg tggttgttct     3180

tcaagcaagt tctgcttgca cttttgcatt tgcctaacag acttttgcag aggcgatggc     3240

agagagcagc tgcaggcatg gtccctggag ccgagccttc accacgcact cgtccaagtt     3300

cggatgcggg aacctggtcc cagcttgagt tcctgccttt cccaccacaa attatcaact     3360

ggttgatgtg tacactaatt acatttcagg aggacttaat gctatttatg ttgtgcctct     3420

gcaggcaaag cccttaataa atattttaca tcctttctaa tgacaatgaa tggaattaat     3480

cactcaacag gtatagtatt acgactcatg tttacttttt aaaatgattt agaccgattt     3540

tcagatttta tttcgttatg attaaagatg tctcatgtac ttggaaaagt gagcattttt     3600

tttttttttg tatttcactt tcataccagg cttaatgtca atgacatttt tatttttgaa     3660

gtactctgac acctccaccc tctactttat tagaattgga aggcaaattt ttgtccaaaa     3720

acctacagac aagtactttg agagaatttc caatataata ttagacataa tgataatttt     3780

ttccatactc agaatgaaaa actggatatt acgtttttgt tttggggttt ttttgtacaa     3840

atttagctaa tagctacagg ctgagagaat tgtaacatag catgacaaat tttgtgttga     3900

cttgaaagga atcacaccat tattccttag aagtaattac atgtgttcta acacatttga     3960

gacagggttg gactcccatt tctcatccga gaaattactt aacccttcct ggcgctgtac     4020

agtcatcttt tattctattt cctctttgct gtttgtagta gagacatttt gaatgaaact     4080

tggcactgct tgattcaaaa ctgtggaaac cagatctgtt tagtctcctg tttgtatgcg     4140

tttgctaatg gtagctaaat aaccagtttt tgttgtaaat gcaccaattc tgaaggcact     4200

ttatgtacta catggaggtc atatctggtt ttgtttttat ttttttatca tgaacattaa     4260

atgtgatgat gatttctttt ccctgcacac atctttccgg tgcaatatct atcaattgtg     4320

aatctggctg ctggtgtata aaaacctgga tgtaaagctg agcctacaga cctgtcctca     4380

ccaactgttt tgtgatttct actcaactac aaagatttat ttaatgtact cttaatctaa     4440

ctgagttttg ttaccaatga cctgttgcat gcttcaatac cgtgtactgc ctgagttgtg     4500

cctcttgtgt gctagattaa aagtgagaca gagacttgac ttgatcctct gagctcaagc     4560

tattgagctg gtagtggcag aggactgagg gtacctgcac agtttgattc ttttccacgt     4620

gtaagtctcc attgcagaat tgtcgtgctt tgagaaaaca cctgaggcag tgtgggagtt     4680

gaacgaccct gctgtccttt ttaacctgtg ttgtcctaga ccctgtcggg gcagtcaggg     4740

gacactagag atttgatctc atgcgagtca tcaataggac aaaaaagttg tggtttgggg     4800

aggtctgttt gttacataaa aaggaccttt cggtgtaaga aattgccgtt tttaccctgc     4860

cctggctggc atgtgagaag ccatggaagg ttgtggttgt aaatgagttg tctaaagggg     4920

tgcagaggcc tgaggtttct aaaagaaggt agatttctac agagctgagt gttggttcct     4980

ttttcttatt ggttgaaaat tacctggtag tgatcagaaa acttagatgc tatgtaacta     5040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaattcc cgctcatgag ttttgactat     5100

tggtgagatg ttttccgcta cagttaacat gacaaatgtc tcagtggcaa aaatcccctt     5160

tttgtaagcc cccatagtct agaggcagtt ttctttttaa gaatcatgcc agagcctgag     5220

tcgagcagta tgctttcttg gtttttgaga gtaattgtgt aattgtagag ggagaaatcc     5280

aattctaacc taagaactgg gattcttctg tcatcttgta aaccgtatat tgaaaaaaac     5340

agaatgtcac taaatgcata ttaagtcaag tattggaaag tataaaagaa aaatcattct     5400

gacaatttct aagccagaag caaacaagaa ttactgaaat ctaccccatg aatacttgga     5460

aggcagtaat tgtgagtgac acctcagttc atcaacccct taataatatc agcttaattt     5520

taatgacaac taaatatgct gaagtgagga tttagtattt tttaaaaaag caaaacaagg     5580

ttcagtagtc ctcagcaatt ctccaagttt ctctctttgc ctaaaatggt catagatctt     5640

gatttctctg aatcgtgatg accacaccca gtcatcttca cagcataatt gcaggtggca     5700

gtaaagagag tgtgctgggt aaggagcagt tgctgggtca ttccttgggc cccgacctgc     5760

ccggggagta gccctggggg agagagggca gtgttgccta tcccagaggt cccagcagtc     5820

acactgctct gcaggccggg ctctctttat agccagagaa atcaccttaa tgcagtctct     5880

ttagttgtct gctgaagctg tagttattat gggccactta catgaggctg agaagtacgt     5940

gccggagctc acacactgcc tgttgcggtt ctcttaacat cagttatcac agctgcctgt     6000

gggtcccggg tatttccatt cctgcccctt gttggcccga ggaaggatgt ggaaagagca     6060

cctggtggga tgaaggtcca acagcctgtg cctctccact gctggccctg gagccggcag     6120

cagtgaggca ttcattgtct gtgttgcggt gtattcccag cttcagtgct cttttccttt     6180

ttgcctgaaa tgtttatgct tctctgcagc cagtcctcta acaaatctca agaacaaagg     6240

taagacactt ggtttttgtt tccaggaccc ttcagaaggt gacatcagat attccctaaa     6300

ttcagacaat gagggataca gagcgacttg gcatgtatta tttctcccat gtaaggacaa     6360

agggacagat tattattgtt atttctgaga cagagtcttg ctctgtagct caggctggag     6420

tgcagtggct caatctcagc tcaccacaac ctctgcctcc tggcttcaag cgattcttct     6480

gcctcagcct ccccgaatag ttgggattac aggcacccac caccacgcct ggctaatttt     6540

tgtattttta gtagagatgg tttcaccatg ctggccaggc tggtcttgaa ctcctgacct     6600

caggtgatcc tcccgcctca gccttccaaa gtgctgggat tacaagcatg agccaccgca     6660

cccggcctca cagtgacaga ttctgagaaa cagcatgcaa aacatttgaa ccattttcta     6720

catctcccat tgttgcatag agagtgtgca ccgctgctat cttgccagat ccacactggt     6780

cctcccgaaa gccaggttca tacacagcaa ctttttaatt attctaacag ttacccatta     6840

acagtcgact cctgtatttc tgagagtctt gtactcacct ctgaaattta aaaacgtata     6900

aagagagcct gggttaatca gttctgcagc ccctacgtga cactgtgcta gttctccttc     6960

ttctgtctcc tccttaccct ggccctgcac ccctgtactt aagagggaga ggtgggaggt     7020

gctgtctggt atcatttgct gcctcgccag tagagggtgc cgctgtgcag ggtaactgcc     7080

cgcctgctcc cttcctgacc tcccctgacc ccgaagatca ctacctctgt cattcaggca     7140

ttggggtaca tcctgataag tcgtgtcaga actgccaatt tcaggactga gatgtgtttt     7200

taaaaaacaa atccttataa actccacttt gtactttaga ttttaaaact ggggaaaaat     7260

gtgatattct ttggaccact tttttaattt atataagcct taatgaacag tgtctataca     7320

tttgcataca cacaccccca ccccagagtg ttctcagtat gtcagagaaa gtgccacagc     7380

attaggacgg gagcttggag aacgttttct agaaaagggt tagcttcctg ttggcatgaa     7440

attttccaag caaacctcat taaacatctg ttgtttgtta aagatgttcc actgaaagca     7500

acgcatgttt caaaggcacg tctttccgtt cgttggtttt ctgtgtgtaa ggagtagcat     7560

tgctgttggc gcctaacctc gcgtgcactg cattctcaac cccgtaccag tgcatcatca     7620

gaagccttcc tcgtgaccat aactctgtgt ctgcagatat gtgttcccgt gtaagccagt     7680

tttccccttt tactcagact gatttcacct agattgtcac ggtttccttc atgttaactt     7740

tgcgtgactt tgttcttcct ttactactct gtatgtaata tatatacata tatacgtaca     7800

tatgctgtcc aaatatattt gtatatattt gtatagcatt tttacacctt tattgagtaa     7860

tctggtttcg aaaggaggtg agagtttagt cccttctgca gttttctcca agctgtgtcc     7920

tgtgaatttc aacccttgga gcctaagaaa accctaggaa gatgatgtta atttgctgtc     7980

atttcctaat tcaggatcta tcatcaaatg aaacatgaaa aaaacagtga cttttaaggt     8040

gaaaagagtt tcaagcattc caaataaatt atcaatgttt cataactttt tattataaac     8100

ccacctccta ataggaagcc aagtactatt tgatacagtg gtaaaaacca aactaccttg     8160

aattttttta aggcaactta tgaataatgc tcattttcac agtcagaata gctttaaaat     8220

atggttgaat ttgatacaca caggaagttt tcttgaagaa caatcctttc gcttttcttt     8280

tttcttgaga gatctaaaga gaaactgtag attgttttcc tgacagcaaa agactaatgt     8340

gacaaaatga agtcattgta aagaagcgat gcaacttgtc aaatatttaa taaagaatta     8400

tggaagctgg aacattttct ac                                              8422


<210>  88
<211>  8361
<212>  DNA
<213>  homo sapiens

<400>  88
acttccgtgt tccccacatt tgaatttgct cccgattcga gagaggcagg catccgcggc       60

agcagcttcc aacccagaca ggcttaagcc gcgcgagggt gcccgggtgg gtggctgcgc      120

agggccctac ctgggcggga gcggctgcag agccctgtcc acgcggtgcc tccccagcac      180

ggcacctccc actccaggct gttggttacc tggccgggag ctggcggaga ccaggatttc      240

tcctcgccgc cgttgctgtt gttaggggaa acagaccatc tgcatctaga cctgcctctc      300

tctccgctcc ccacttcaga cgagctcttc ctgcctggaa tctgtgatcc gtatgtgaaa      360

ctttcattgt acgtagcgga tgagaataga gaacttgctt tggtccagac aaaaacaatt      420

aaaaagacac tgaacccaaa atggaatgaa gaattttatt tcagggtaaa cccatctaat      480

cacagactcc tatttgaagt atttgacgaa aatagactga cacgagacga cttcctgggc      540

caggtggacg tgccccttag tcaccttccg acagaagatc caaccatgga gcgaccctat      600

acatttaagg actttctcct cagaccaaga agtcataagt ctcgagttaa gggatttttg      660

cgattgaaaa tggcctatat gccaaaaaat ggaggtcaag atgaagaaaa cagtgaccag      720

agggatgaca tggagcatgg atgggaagtt gttgactcaa atgactcggc ttctcagcac      780

caagaggaac ttcctcctcc tcctctgcct cccgggtggg aagaaaaagt ggacaattta      840

ggccgaactt actatgtcaa ccacaacaac cggaccactc agtggcacag accaagcctg      900

atggacgtgt cctcggagtc ggacaataac atcagacaga tcaaccagga ggcagcacac      960

cggcgcttcc gctcccgcag gcacatcagc gaagacttgg agcccgagcc ctcggagggc     1020

ggggatgtcc ccgagccttg ggagaccatt tcagaggaag tgaatatcgc tggagactct     1080

ctcggtctgg ctctgccccc accaccggcc tccccaggat ctcggaccag ccctcaggag     1140

ctgtcagagg aactaagcag aaggcttcag atcactccag actccaatgg ggaacagttc     1200

agctctttga ttcaaagaga accctcctca aggttgaggt catgcagtgt caccgacgca     1260

gttgcagaac agggccatct accaccgcca tcagtggcct atgtacatac cacgccgggt     1320

ctgccttcag gctgggaaga aagaaaagat gctaaggggc gcacatacta tgtcaatcat     1380

aacaatcgaa ccacaacttg gactcgacct atcatgcagc ttgcagaaga tggtgcgtcc     1440

ggatcagcca caaacagtaa caaccatcta atcgagcctc agatccgccg gcctcgtagc     1500

ctcagctcgc caacagtaac tttatctgcc ccgctggagg gtgccaagga ctcacccgta     1560

cgtcgggctg tgaaagacac cctttccaac ccacagtccc cacagccatc accttacaac     1620

tcccccaaac cacaacacaa agtcacacag agcttcttgc cacccggctg ggaaatgagg     1680

atagcgccaa acggccggcc cttcttcatt gatcataaca caaagactac aacctgggaa     1740

gatccacgtt tgaaatttcc agtacatatg cggtcaaaga catctttaaa ccccaatgac     1800

cttggccccc ttcctcctgg ctgggaagaa agaattcact tggatggccg aacgttttat     1860

attgatcata atagcaaaat tactcagtgg gaagacccaa gactgcagaa cccagctatt     1920

actggtccgg ctgtccctta ctccagagaa tttaagcaga aatatgacta cttcaggaag     1980

aaattaaaga aacctgctga tatccccaat aggtttgaaa tgaaacttca cagaaataac     2040

atatttgaag agtcctatcg gagaattatg tccgtgaaaa gaccagatgt cctaaaagct     2100

agactgtgga ttgagtttga atcagagaaa ggtcttgact atgggggtgt ggccagagaa     2160

tggttcttct tactgtccaa agagatgttc aacccctact acggcctctt tgagtactct     2220

gccacggaca actacaccct tcagatcaac cctaattcag gcctctgtaa tgaggatcat     2280

ttgtcctact tcacttttat tggaagagtt gctggtctgg ccgtatttca tgggaagctc     2340

ttagatggtt tcttcattag accattttac aagatgatgt tgggaaagca gataaccctg     2400

aatgacatgg aatctgtgga tagtgaatat tacaactctt tgaaatggat cctggagaat     2460

gaccctactg agctggacct catgttctgc atagacgaag aaaactttgg acagacatat     2520

caagtggatt tgaagcccaa tgggtcagaa ataatggtca caaatgaaaa caaaagggaa     2580

tatatcgact tagtcatcca gtggagattt gtgaacaggg tccagaagca gatgaacgcc     2640

ttcttggagg gattcacaga actacttcct attgatttga ttaaaatttt tgatgaaaat     2700

gagctggagt tgctcatgtg cggcctcggt gatgtggatg tgaatgactg gagacagcat     2760

tctatttaca agaacggcta ctgcccaaac caccccgtca ttcagtggtt ctggaaggct     2820

gtgctactca tggacgccga aaagcgtatc cggttactgc agtttgtcac agggacatcg     2880

cgagtaccta tgaatggatt tgccgaactt tatggttcca atggtcctca gctgtttaca     2940

atagagcaat ggggcagtcc tgagaaactg cccagagctc acacatgctt taatcgcctt     3000

gacttacctc catatgaaac ctttgaagat ttacgagaga aacttctcat ggccgtggaa     3060

aatgctcaag gatttgaagg ggtggattaa gcaccctgtg cctcgggggt ggttgttctt     3120

caagcaagtt ctgcttgcac ttttgcattt gcctaacaga cttttgcaga ggcgatggca     3180

gagagcagct gcaggcatgg tccctggagc cgagccttca ccacgcactc gtccaagttc     3240

ggatgcggga acctggtccc agcttgagtt cctgcctttc ccaccacaaa ttatcaactg     3300

gttgatgtgt acactaatta catttcagga ggacttaatg ctatttatgt tgtgcctctg     3360

caggcaaagc ccttaataaa tattttacat cctttctaat gacaatgaat ggaattaatc     3420

actcaacagg tatagtatta cgactcatgt ttacttttta aaatgattta gaccgatttt     3480

cagattttat ttcgttatga ttaaagatgt ctcatgtact tggaaaagtg agcatttttt     3540

ttttttttgt atttcacttt cataccaggc ttaatgtcaa tgacattttt atttttgaag     3600

tactctgaca cctccaccct ctactttatt agaattggaa ggcaaatttt tgtccaaaaa     3660

cctacagaca agtactttga gagaatttcc aatataatat tagacataat gataattttt     3720

tccatactca gaatgaaaaa ctggatatta cgtttttgtt ttggggtttt tttgtacaaa     3780

tttagctaat agctacaggc tgagagaatt gtaacatagc atgacaaatt ttgtgttgac     3840

ttgaaaggaa tcacaccatt attccttaga agtaattaca tgtgttctaa cacatttgag     3900

acagggttgg actcccattt ctcatccgag aaattactta acccttcctg gcgctgtaca     3960

gtcatctttt attctatttc ctctttgctg tttgtagtag agacattttg aatgaaactt     4020

ggcactgctt gattcaaaac tgtggaaacc agatctgttt agtctcctgt ttgtatgcgt     4080

ttgctaatgg tagctaaata accagttttt gttgtaaatg caccaattct gaaggcactt     4140

tatgtactac atggaggtca tatctggttt tgtttttatt tttttatcat gaacattaaa     4200

tgtgatgatg atttcttttc cctgcacaca tctttccggt gcaatatcta tcaattgtga     4260

atctggctgc tggtgtataa aaacctggat gtaaagctga gcctacagac ctgtcctcac     4320

caactgtttt gtgatttcta ctcaactaca aagatttatt taatgtactc ttaatctaac     4380

tgagttttgt taccaatgac ctgttgcatg cttcaatacc gtgtactgcc tgagttgtgc     4440

ctcttgtgtg ctagattaaa agtgagacag agacttgact tgatcctctg agctcaagct     4500

attgagctgg tagtggcaga ggactgaggg tacctgcaca gtttgattct tttccacgtg     4560

taagtctcca ttgcagaatt gtcgtgcttt gagaaaacac ctgaggcagt gtgggagttg     4620

aacgaccctg ctgtcctttt taacctgtgt tgtcctagac cctgtcgggg cagtcagggg     4680

acactagaga tttgatctca tgcgagtcat caataggaca aaaaagttgt ggtttgggga     4740

ggtctgtttg ttacataaaa aggacctttc ggtgtaagaa attgccgttt ttaccctgcc     4800

ctggctggca tgtgagaagc catggaaggt tgtggttgta aatgagttgt ctaaaggggt     4860

gcagaggcct gaggtttcta aaagaaggta gatttctaca gagctgagtg ttggttcctt     4920

tttcttattg gttgaaaatt acctggtagt gatcagaaaa cttagatgct atgtaactaa     4980

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaattccc gctcatgagt tttgactatt     5040

ggtgagatgt tttccgctac agttaacatg acaaatgtct cagtggcaaa aatccccttt     5100

ttgtaagccc ccatagtcta gaggcagttt tctttttaag aatcatgcca gagcctgagt     5160

cgagcagtat gctttcttgg tttttgagag taattgtgta attgtagagg gagaaatcca     5220

attctaacct aagaactggg attcttctgt catcttgtaa accgtatatt gaaaaaaaca     5280

gaatgtcact aaatgcatat taagtcaagt attggaaagt ataaaagaaa aatcattctg     5340

acaatttcta agccagaagc aaacaagaat tactgaaatc taccccatga atacttggaa     5400

ggcagtaatt gtgagtgaca cctcagttca tcaacccctt aataatatca gcttaatttt     5460

aatgacaact aaatatgctg aagtgaggat ttagtatttt ttaaaaaagc aaaacaaggt     5520

tcagtagtcc tcagcaattc tccaagtttc tctctttgcc taaaatggtc atagatcttg     5580

atttctctga atcgtgatga ccacacccag tcatcttcac agcataattg caggtggcag     5640

taaagagagt gtgctgggta aggagcagtt gctgggtcat tccttgggcc ccgacctgcc     5700

cggggagtag ccctggggga gagagggcag tgttgcctat cccagaggtc ccagcagtca     5760

cactgctctg caggccgggc tctctttata gccagagaaa tcaccttaat gcagtctctt     5820

tagttgtctg ctgaagctgt agttattatg ggccacttac atgaggctga gaagtacgtg     5880

ccggagctca cacactgcct gttgcggttc tcttaacatc agttatcaca gctgcctgtg     5940

ggtcccgggt atttccattc ctgccccttg ttggcccgag gaaggatgtg gaaagagcac     6000

ctggtgggat gaaggtccaa cagcctgtgc ctctccactg ctggccctgg agccggcagc     6060

agtgaggcat tcattgtctg tgttgcggtg tattcccagc ttcagtgctc ttttcctttt     6120

tgcctgaaat gtttatgctt ctctgcagcc agtcctctaa caaatctcaa gaacaaaggt     6180

aagacacttg gtttttgttt ccaggaccct tcagaaggtg acatcagata ttccctaaat     6240

tcagacaatg agggatacag agcgacttgg catgtattat ttctcccatg taaggacaaa     6300

gggacagatt attattgtta tttctgagac agagtcttgc tctgtagctc aggctggagt     6360

gcagtggctc aatctcagct caccacaacc tctgcctcct ggcttcaagc gattcttctg     6420

cctcagcctc cccgaatagt tgggattaca ggcacccacc accacgcctg gctaattttt     6480

gtatttttag tagagatggt ttcaccatgc tggccaggct ggtcttgaac tcctgacctc     6540

aggtgatcct cccgcctcag ccttccaaag tgctgggatt acaagcatga gccaccgcac     6600

ccggcctcac agtgacagat tctgagaaac agcatgcaaa acatttgaac cattttctac     6660

atctcccatt gttgcataga gagtgtgcac cgctgctatc ttgccagatc cacactggtc     6720

ctcccgaaag ccaggttcat acacagcaac tttttaatta ttctaacagt tacccattaa     6780

cagtcgactc ctgtatttct gagagtcttg tactcacctc tgaaatttaa aaacgtataa     6840

agagagcctg ggttaatcag ttctgcagcc cctacgtgac actgtgctag ttctccttct     6900

tctgtctcct ccttaccctg gccctgcacc cctgtactta agagggagag gtgggaggtg     6960

ctgtctggta tcatttgctg cctcgccagt agagggtgcc gctgtgcagg gtaactgccc     7020

gcctgctccc ttcctgacct cccctgaccc cgaagatcac tacctctgtc attcaggcat     7080

tggggtacat cctgataagt cgtgtcagaa ctgccaattt caggactgag atgtgttttt     7140

aaaaaacaaa tccttataaa ctccactttg tactttagat tttaaaactg gggaaaaatg     7200

tgatattctt tggaccactt ttttaattta tataagcctt aatgaacagt gtctatacat     7260

ttgcatacac acacccccac cccagagtgt tctcagtatg tcagagaaag tgccacagca     7320

ttaggacggg agcttggaga acgttttcta gaaaagggtt agcttcctgt tggcatgaaa     7380

ttttccaagc aaacctcatt aaacatctgt tgtttgttaa agatgttcca ctgaaagcaa     7440

cgcatgtttc aaaggcacgt ctttccgttc gttggttttc tgtgtgtaag gagtagcatt     7500

gctgttggcg cctaacctcg cgtgcactgc attctcaacc ccgtaccagt gcatcatcag     7560

aagccttcct cgtgaccata actctgtgtc tgcagatatg tgttcccgtg taagccagtt     7620

ttcccctttt actcagactg atttcaccta gattgtcacg gtttccttca tgttaacttt     7680

gcgtgacttt gttcttcctt tactactctg tatgtaatat atatacatat atacgtacat     7740

atgctgtcca aatatatttg tatatatttg tatagcattt ttacaccttt attgagtaat     7800

ctggtttcga aaggaggtga gagtttagtc ccttctgcag ttttctccaa gctgtgtcct     7860

gtgaatttca acccttggag cctaagaaaa ccctaggaag atgatgttaa tttgctgtca     7920

tttcctaatt caggatctat catcaaatga aacatgaaaa aaacagtgac ttttaaggtg     7980

aaaagagttt caagcattcc aaataaatta tcaatgtttc ataacttttt attataaacc     8040

cacctcctaa taggaagcca agtactattt gatacagtgg taaaaaccaa actaccttga     8100

atttttttaa ggcaacttat gaataatgct cattttcaca gtcagaatag ctttaaaata     8160

tggttgaatt tgatacacac aggaagtttt cttgaagaac aatcctttcg cttttctttt     8220

ttcttgagag atctaaagag aaactgtaga ttgttttcct gacagcaaaa gactaatgtg     8280

acaaaatgaa gtcattgtaa agaagcgatg caacttgtca aatatttaat aaagaattat     8340

ggaagctgga acattttcta c                                               8361


<210>  89
<211>  1788
<212>  DNA
<213>  homo sapiens

<400>  89
gtacggcctg tccggcgctc gacgttccac ccccctctct ctgctctcag gttggttcag       60

cccccgtcta cactggggtg gtgcttagcc ggcgccagac cgaccctcga cttcggagag      120

gcagcgcggt tcctctgggt gcttccgcct ccccttctcc tgcttctcca gcctcttcgg      180

cctcctcgcc cgccgcggga acccgagacc ccagtgtatg ccccacccct gaccccgctc      240

gcgacatgtc caccccggct cggcggcgcc tcatgcggga cttcaagagg ttgcaggagg      300

atcctccagc cggagtcagc ggggctccgt ccgagaacaa cataatggtg tggaacgcgg      360

tcattttcgg gcctgaaggg accccgtttg aggatgtcta tgcagatggt agtatatgtc      420

tggacatact tcagaaccgt tggagtccaa cctatgatgt gtcttccatt ctaacatcca      480

tacagtctct gttggatgaa cccaatccca atagtccagc aaacagccag gctgctcagc      540

tgtaccagga gaacaaacgg gaatatgaaa agcgtgtttc tgcaatagta gaacaaagct      600

ggcgtgattg ttgaccccgg gtacagttta aagaagctgg ccataagaaa aatatatatt      660

gatgtgtttg tcacctccct actcctgtca ttacatttac tttattaaaa gcaaaataac      720

tgttgtgctg tttccatctt ccttgccaag ttttcctacc ccttctaccc tctccttaaa      780

catcagaaaa caccctctat gaaatcaaat gtactgtacc tgggttactt gcaaaaatta      840

ctaatgcttc agtttttctg ttgtatttca tttccagttt tcaggcagtt atttttatta      900

ttgtacttta agcttttaag atgaattgtt atacaagagg tgcttatgct tagcttgatg      960

accaggatgt tatttttaac aaaatgattg ctgaagtgtt tcatcctggc tggtccttca     1020

cttgtgttgg atttagaagt gaatgtgttt ggaatatggc ctacagagaa tagaaacaaa     1080

tccatgtaaa caattttgaa ggaggcatgg gagctaaaaa tcctgtgata ctaagatctc     1140

agtcatatga attacaacgt agtatttact ggcaagaagg agaaagttga aggactcagc     1200

taaaggagta cagcaattgt agtaactgac acatcctctc tttgcaagct gctgactggg     1260

cacactcatg ccaagtttca gaattattgg tcttctgggt ttttgctttt taaaagaggt     1320

gtgggagcag aggaatggaa acaatcgtga gtttttgagc tagggaaagt tggagctcct     1380

ttaatctttt taaaggatca gtgctgccct aagtgaataa actcaattgt ccatctttat     1440

tttagagttt taatgaattc aaggaaggga gcatagcata tctgtggcaa actattttcc     1500

actcaaatcc tgagttattg ctgcatgctt taatttcttc cctttcagca tctgagaacc     1560

ttaaagccaa tgtctgcgat ctttttttgg atatttatac ttttagatat atagtacctt     1620

taagtagcag tatgggacaa ggcttgtaaa tgttttgtct aatgttctat tgtcaccttt     1680

tatgcattta tcacttccaa atctaacttt gcacaagtaa cccatgtaaa aaaaaatgta     1740

catttttcaa aagttgtaaa taaaaataac cttaaaattt catagtca                  1788


<210>  90
<211>  7658
<212>  DNA
<213>  homo sapiens

<400>  90
gctcactcgc tcaactcggc gccgccgcgg ccccacgctc cgggcccgtc ctcgaggcgc       60

gcggcgcggg gcgcgggcgc cggggcctga ggcggcgggc gacgcccggg ggcctgacgg      120

ccggccccgc gccatggtgt gagcgccgcc gcccgtgcac gctccgtccg ccctccgcgc      180

ggcccggccg gcagagagcc ccgagcggcc cgagagcgca gccgagcccg ccgccgccgc      240

ccgcggcccc gcgaggagag taccgggccg gctcggctgc cgcgcgagga gcgcggtcgg      300

cggcctggtc tgcggctgag atacacagag cgacagagac atttattgtt atttgttttt      360

tggtggcaaa aagggaaaat ggcgaacgac tcccctgcaa aaagtctggt ggacatcgac      420

ctctcctccc tgcgggatcc tgctgggatt tttgagctgg tggaagtggt tggaaatggc      480

acctatggac aagtctataa gggtcgacat gttaaaacgg gtcagttggc agccatcaaa      540

gttatggatg tcactgagga tgaagaggaa gaaatcaaac tggagataaa tatgctaaag      600

aaatactctc atcacagaaa cattgcaaca tattatggtg ctttcatcaa aaagagccct      660

ccaggacatg atgaccaact ctggcttgtt atggagttct gtggggctgg gtccattaca      720

gaccttgtga agaacaccaa agggaacaca ctcaaagaag actggatcgc ttacatctcc      780

agagaaatcc tgaggggact ggcacatctt cacattcatc atgtgattca ccgggatatc      840

aagggccaga atgtgttgct gactgagaat gcagaggtga aacttgttga ctttggtgtg      900

agtgctcagc tggacaggac tgtggggcgg agaaatacgt tcataggcac tccctactgg      960

atggctcctg aggtcatcgc ctgtgatgag aacccagatg ccacctatga ttacagaagt     1020

gatctttggt cttgtggcat tacagccatt gagatggcag aaggtgctcc ccctctctgt     1080

gacatgcatc caatgagagc actgtttctc attcccagaa accctcctcc ccggctgaag     1140

tcaaaaaaat ggtcgaagaa gttttttagt tttatagaag ggtgcctggt gaagaattac     1200

atgcagcggc cctctacaga gcagcttttg aaacatcctt ttataaggga tcagccaaat     1260

gaaaggcaag ttagaatcca gcttaaggat catatagatc gtaccaggaa gaagagaggc     1320

gagaaagatg aaactgagta tgagtacagt gggagtgagg aagaagagga ggaagtgcct     1380

gaacaggaag gagagccaag ttccattgtg aacgtgcctg gtgagtctac tcttcgccga     1440

gatttcctga gactgcagca ggagaacaag gaacgttccg aggctcttcg gagacaacag     1500

ttactacagg agcaacagct ccgggagcag gaagaatata aaaggcaact gctggcagag     1560

agacagaagc ggattgagca gcagaaagaa cagaggcgac ggctagaaga gcaacaaagg     1620

agagagcggg aagctagaag gcagcaggaa cgtgaacagc gaaggagaga acaagaagaa     1680

aagaggcgtc tagaggagtt ggagagaagg cgcaaagaag aagaggagag gagacgggca     1740

gaagaagaaa agaggagagt tgaaagagaa caggagtata tcaggcgaca gctagaagag     1800

gagcagcggc acttggaagt ccttcagcag cagctgctcc aggagcaggc catgttactg     1860

catgaccata ggaggccgca cccgcagcac tcgcagcagc cgccaccacc gcagcaggaa     1920

aggagcaagc caagcttcca tgctcccgag cccaaagccc actacgagcc tgctgaccga     1980

gcgcgagagg tggaagatag atttaggaaa actaaccaca gctcccctga agcccagtct     2040

aagcagacag gcagagtatt ggagccacca gtgccttccc gatcagagtc tttttccaat     2100

ggcaactccg agtctgtgca tcccgccctg cagagaccag cggagccaca ggttcctgtg     2160

agaacaacat ctcgctcccc tgttctgtcc cgtcgagatt ccccactgca gggcagtggg     2220

cagcagaata gccaggcagg acagagaaac tccaccagca gtattgagcc caggcttctg     2280

tgggagagag tggagaagct ggtgcccaga cctggcagtg gcagctcctc agggtccagc     2340

aactcaggat cccagcccgg gtctcaccct gggtctcaga gtggctccgg ggaacgcttc     2400

agagtgagat catcatccaa gtctgaaggc tctccatctc agcgcctgga aaatgcagtg     2460

aaaaaacctg aagataaaaa ggaagttttc agacccctca agcctgctga tctgaccgca     2520

ctggccaaag agcttcgagc agtggaagat gtacggccac ctcacaaagt aacggactac     2580

tcctcatcca gtgaggagtc ggggacgacg gatgaggagg acgacgatgt ggagcaggaa     2640

ggggctgacg agtccacctc aggaccagag gacaccagag cagcgtcatc tctgaatttg     2700

agcaatggtg aaacggaatc tgtgaaaacc atgattgtcc atgatgatgt agaaagtgag     2760

ccggccatga ccccatccaa ggagggcact ctaatcgtcc gccagagtac agttgaccaa     2820

aagcgtgcca gccatcatga gagcaatggc tttgccggtc gcattcacct cttgccagat     2880

ctcttacagc aaagccattc ctcctccact tcctccacct cctcctcccc atcctccagc     2940

cagccgacac ccaccatgtc cccacagaca ccccaggaca agctcactgc taatgagact     3000

cagtccgcta gtagcacact ccagaaacac aaatcttcct cctcctttac accttttata     3060

gaccccagat tactacagat ttctccatct agcggaacaa cagtgacatc tgtggtggga     3120

ttttcctgtg atgggatgag accagaagcc ataaggcaag atcctacccg gaaaggctca     3180

gtggtcaatg tgaatcctac caacactagg ccacagagtg acaccccgga gattcgtaaa     3240

tacaagaaga ggtttaactc tgagattctg tgtgctgcct tatggggagt gaatttgcta     3300

gtgggtacag agagtggcct gatgctgctg gacagaagtg gccaagggaa ggtctatcct     3360

cttatcaacc gaagacgatt tcaacaaatg gacgtacttg agggcttgaa tgtcttggtg     3420

acaatatctg gcaaaaagga taagttacgt gtctactatt tgtcctggtt aagaaataaa     3480

atacttcaca atgatccaga agttgagaag aagcagggat ggacaaccgt aggggatttg     3540

gaaggatgtg tacattataa agttgtaaaa tatgaaagaa tcaaatttct ggtgattgct     3600

ttgaagagtt ctgtggaagt ctatgcgtgg gcaccaaagc catatcacaa atttatggcc     3660

tttaagtcat ttggagaatt ggtacataag ccattactgg tggatctcac tgttgaggaa     3720

ggccagaggt tgaaagtgat ctatggatcc tgtgctggat tccatgctgt tgatgtggat     3780

tcaggatcag tctatgacat ttatctacca acacatatcc agtgtagcat caaaccccat     3840

gcaatcatca tcctccccaa tacagatgga atggagcttc tggtgtgcta tgaagatgag     3900

ggggtttatg taaacacata tggaaggatc accaaggatg tagttctaca gtggggagag     3960

atgcctacat cagtagcata tattcgatcc aatcagacaa tgggctgggg agagaaggcc     4020

atagagatcc gatctgtgga aactggtcac ttggatggtg tgttcatgca caaaagggct     4080

caaagactaa aattcttgtg tgaacgcaat gacaaggtgt tctttgcctc tgttcggtct     4140

ggtggcagca gtcaggttta tttcatgacc ttaggcagga cttctcttct gagctggtag     4200

aagcagtgtg atccagggat tactggcctc cagagtcttc aagatcctga gaacttggaa     4260

ttccttgtaa ctggagctcg gagctgcacc gagggcaacc aggacagctg tgtgtgcaga     4320

cctcatgtgt tgggttctct cccctccttc ctgttcctct tatataccag tttatcccca     4380

ttcttttttt ttttcttact ccaaaataaa tcaaggctgc aatgcagctg gtgctgttca     4440

gattctacca tcaggtgcta taagtgtttg ggattgagca tcatactgga aagcaaacac     4500

ctttcctcca gctccagaat tccttgtctc tgaatgactc tgtcttgtgg gtgtctgaca     4560

gtggcgacga tgaacatgcc gttggtttta ttggcagtgg gcacaaggag gtgagaagtg     4620

gtggtaaaag gagcggagtg ctgaagcaga gagcagattt aatatagtaa cattaacagt     4680

gtatttaatt gacatttctt ttttgtaatg tgacgatatg tggacaaaga agaagatgca     4740

ggtttaagaa gttaatattt ataaaatgtg aaagacacag ttactaggat aacttttttg     4800

tgggtggggc ttgggagatg gggtggggtg ggttaagggg tcccattttg tttctttgga     4860

tttggggtgg gggtcctggc caagaactca gtcatttttc tgtgtaccag gttgcctaaa     4920

tcatgtgcag atggttctaa aaaaaaaaaa aaaaaaaaaa aaaaaaggaa aaaaaaaaag     4980

aaaaagaaaa cgtgtgcatt ttgtataatg gccagaactt tgtcgtgtga cagtattagc     5040

actgcctcag ttaaaggttt aatttttgtt taaacctaga cgtgcaacaa aagttttacc     5100

acagtctgca cttgcagaag aaagaaaaaa attcaaacca catgtttatt ttttttttgc     5160

ctacctcatt gttcttaatg cattgagagg tgatttagtt tatatgtttt tggaagaaac     5220

cattaatgtt taatttaatc ttaataccaa aacgaccaga ttgaagtttg acttttattg     5280

tcacaaatca gcaggcacaa gaactgtcca tgaagatggg aaatagcctt aaggctgatg     5340

cagtttactt acaagtttag aaaccagaat gctttgtttt taccagattc accattagag     5400

gttgatgggg caactgcagc ccatgacaca agatctcatt gttctcgatg tagaggggtt     5460

ggtagcagac aggtggttac attagaatag tcacacaaac tgttcagtgt tgcaggaacc     5520

ttttcttggg ggtgggggag tttccctttt ctaaaaatgc aatgcactaa aactatttta     5580

agaatgtagt taattctgct tattcataaa gtgggcatct tctgtgtttt aggtgtaata     5640

tcgaagtcct ggcttttctc gttttctcac ttgctctctt gttctctgtt tttttaaacc     5700

aattttactt tatgaatata ttcatgacat ttgtaataaa tgtcttgaga aagaatttgt     5760

ttcatggctt catggtcatc actcaagctc ccgtaaggat attaccgtct caggaaagga     5820

tcaggactcc atgtcacagt cctgccatct tactttcctc ttgtcgagtt ctgagtggaa     5880

ataactgcat tatggctgct ttaacctcag tcatcaaaag aaacttgctg ttttttaggc     5940

ttgatctttt tcctttgtgg ttaattttcc tgtatattgt gaaaatgggg gattttccct     6000

ctgctcccac ccacctaaac acagcagcca tttgtacctg tttgcttccc atcccacttg     6060

gcacccactc tgacctcttg tcagtttcct gttcctggtt ccatcttttt gaaaaaggcc     6120

ctcctttgag ctacaaacat ctggtaagac aagtacatcc actcatgaat gcagacacag     6180

cagctggtgg ttttgtgtat acctgtaaag acaagctgag aagcttactt tttggggaag     6240

taaaagaaga tggaaatgga tgtttcattt gtatgagttt ggagcagtgc tgaaggccaa     6300

agccgcctac tggtttgtag ttaacctaga gaaggttgaa aaattaatcc tacctttaaa     6360

gggatttgag gtaggctgga ttccatcgcc acaggacttt agttagaatt aaattcctgc     6420

ttgtaattta tatccatgtt taggcttttc ataagatgaa acatgccaca gtgaacacac     6480

tcgtgtacat atcaagagaa gaaggaaagg cacaggtgga gaacagtaaa aggtgggcag     6540

atgtctttga agaaatgctc aatgtctgat gctaagtggg agaaggcaga gaacaaagga     6600

tgtggcataa tggtcttaac attatccaaa gacttgaagc tccatgtctg taagtcaaat     6660

gttacacaaa aaaaaatgca aatggtgttt cattggaatt accaagtgct tagaacttgc     6720

tggctttccc ataggtggta aaggggtctg agctcacacc gagttgtgct tggcttgctt     6780

gtgcagctcc aggcacccgg tgggcactct ggtggtgttt gtggtgaact gaattgaatc     6840

cattgttggg cttaagttac tgaaattgga acaccctttg tccttctcgg cgggggcttc     6900

ctggtctgtg ctttacttgg cttttttcct tcccgtctta gcctcacccc cttgtcaacc     6960

agattgagtt gctatagctt gatgcaggga cccagtgaag tttctccgtt aaagattggg     7020

agtcgtcgaa atgtttagat tcttttagga aaggaattat tttcccccct tttacagggt     7080

agtaacttct ccacagaagt gccaatatgg caaaattaca caagaaaaca gtattgcaat     7140

gacaccatta cataaggaac attgaactgt tagaggagtg ctcttccaaa caaaacaaaa     7200

atgtctctag gtttagtcag agctttcaca agtaataacc tttctgtatt aaaatcagag     7260

taaccctttc tgtattgagt gcagtgtttt ttactctttt ctcatgcaca tgttacgttg     7320

gagaaaatgt ttacaaaaat ggttttgtta cactaatgcg caccacatat ttatggttta     7380

ttttaagtga ctttttatgg gttatttagg ttttcgtctt agttgtagca cacttaccct     7440

aattttgcca attattaatt tgctaaatag taatacaaat gacaaactgc attaaattta     7500

ctaattataa aagctgcaaa gcagactggt ggcaagtaca cagccctttt ttttgcagtg     7560

ctaacttgtc tactgtgtat tatgaaaatt actgttgtcc ccccaccctt ttttccttaa     7620

ataaagtaaa aatgacacct aaaaaaaaaa aaaaaaaa                             7658


<210>  91
<211>  7102
<212>  DNA
<213>  homo sapiens

<400>  91
ggaaaatggc gaacgactcc cctgcaaaaa gtctggtgga catcgacctc tcctccctgc       60

gggatcctgc tgggattttt gagctggtgg aagtggttgg aaatggcacc tatggacaag      120

tctataaggg tcgacatgtt aaaacgggtc agttggcagc catcaaagtt atggatgtca      180

ctgaggatga agaggaagaa atcaaactgg agataaatat gctaaagaaa tactctcatc      240

acagaaacat tgcaacatat tatggtgctt tcatcaaaaa gagccctcca ggacatgatg      300

accaactctg gcttgttatg gagttctgtg gggctgggtc cattacagac cttgtgaaga      360

acaccaaagg gaacacactc aaagaagact ggatcgctta catctccaga gaaatcctga      420

ggggactggc acatcttcac attcatcatg tgattcaccg ggatatcaag ggccagaatg      480

tgttgctgac tgagaatgca gaggtgaaac ttgttgactt tggtgtgagt gctcagctgg      540

acaggactgt ggggcggaga aatacgttca taggcactcc ctactggatg gctcctgagg      600

tcatcgcctg tgatgagaac ccagatgcca cctatgatta cagaagtgat ctttggtctt      660

gtggcattac agccattgag atggcagaag gtgctccccc tctctgtgac atgcatccaa      720

tgagagcact gtttctcatt cccagaaacc ctcctccccg gctgaagtca aaaaaatggt      780

cgaagaagtt ttttagtttt atagaagggt gcctggtgaa gaattacatg cagcggccct      840

ctacagagca gcttttgaaa catcctttta taagggatca gccaaatgaa aggcaagtta      900

gaatccagct taaggatcat atagatcgta ccaggaagaa gagaggcgag aaagatgaaa      960

ctgagtatga gtacagtggg agtgaggaag aagaggagga agtgcctgaa caggaaggag     1020

agccaagttc cattgtgaac gtgcctggtg agtctactct tcgccgagat ttcctgagac     1080

tgcagcagga gaacaaggaa cgttccgagg ctcttcggag acaacagtta ctacaggagc     1140

aacagctccg ggagcaggaa gaatataaaa ggcaactgct ggcagagaga cagaagcgga     1200

ttgagcagca gaaagaacag aggcgacggc tagaagagca acaaaggaga gagcgggaag     1260

ctagaaggca gcaggaacgt gaacagcgaa ggagagaaca agaagaaaag aggcgtctag     1320

aggagttgga gagaaggcgc aaagaagaag aggagaggag acgggcagaa gaagaaaaga     1380

ggagagttga aagagaacag gagtatatca ggcgacagct agaagaggag cagcggcact     1440

tggaagtcct tcagcagcag ctgctccagg agcaggccat gttactgcat gaccatagga     1500

ggccgcaccc gcagcactcg cagcagccgc caccaccgca gcaggaaagg agcaagccaa     1560

gcttccatgc tcccgagccc aaagcccact acgagcctgc tgaccgagcg cgagaggtgg     1620

aagatagatt taggaaaact aaccacagct cccctgaagc ccagtctaag cagacaggca     1680

gagtattgga gccaccagtg ccttcccgat cagagtcttt ttccaatggc aactccgagt     1740

ctgtgcatcc cgccctgcag agaccagcgg agccacaggt tcctgtgaga acaacatctc     1800

gctcccctgt tctgtcccgt cgagattccc cactgcaggg cagtgggcag cagaatagcc     1860

aggcaggaca gagaaactcc accagcagta ttgagcccag gcttctgtgg gagagagtgg     1920

agaagctggt gcccagacct ggcagtggca gctcctcagg gtccagcaac tcaggatccc     1980

agcccgggtc tcaccctggg tctcagagtg gctccgggga acgcttcaga gtgagatcat     2040

catccaagtc tgaaggctct ccatctcagc gcctggaaaa tgcagtgaaa aaacctgaag     2100

ataaaaagga agttttcaga cccctcaagc ctgctggcga agtggatctg accgcactgg     2160

ccaaagagct tcgagcagtg gaagatgtac ggccacctca caaagtaacg gactactcct     2220

catccagtga ggagtcgggg acgacggatg aggaggacga cgatgtggag caggaagggg     2280

ctgacgagtc cacctcagga ccagaggaca ccagagcagc gtcatctctg aatttgagca     2340

atggtgaaac ggaatctgtg aaaaccatga ttgtccatga tgatgtagaa agtgagccgg     2400

ccatgacccc atccaaggag ggcactctaa tcgtccgcca gactcagtcc gctagtagca     2460

cactccagaa acacaaatct tcctcctcct ttacaccttt tatagacccc agattactac     2520

agatttctcc atctagcgga acaacagtga catctgtggt gggattttcc tgtgatggga     2580

tgagaccaga agccataagg caagatccta cccggaaagg ctcagtggtc aatgtgaatc     2640

ctaccaacac taggccacag agtgacaccc cggagattcg taaatacaag aagaggttta     2700

actctgagat tctgtgtgct gccttatggg gagtgaattt gctagtgggt acagagagtg     2760

gcctgatgct gctggacaga agtggccaag ggaaggtcta tcctcttatc aaccgaagac     2820

gatttcaaca aatggacgta cttgagggct tgaatgtctt ggtgacaata tctggcaaaa     2880

aggataagtt acgtgtctac tatttgtcct ggttaagaaa taaaatactt cacaatgatc     2940

cagaagttga gaagaagcag ggatggacaa ccgtagggga tttggaagga tgtgtacatt     3000

ataaagttgt aaaatatgaa agaatcaaat ttctggtgat tgctttgaag agttctgtgg     3060

aagtctatgc gtgggcacca aagccatatc acaaatttat ggcctttaag tcatttggag     3120

aattggtaca taagccatta ctggtggatc tcactgttga ggaaggccag aggttgaaag     3180

tgatctatgg atcctgtgct ggattccatg ctgttgatgt ggattcagga tcagtctatg     3240

acatttatct accaacacat atccagtgta gcatcaaacc ccatgcaatc atcatcctcc     3300

ccaatacaga tggaatggag cttctggtgt gctatgaaga tgagggggtt tatgtaaaca     3360

catatggaag gatcaccaag gatgtagttc tacagtgggg agagatgcct acatcagtag     3420

catatattcg atccaatcag acaatgggct ggggagagaa ggccatagag atccgatctg     3480

tggaaactgg tcacttggat ggtgtgttca tgcacaaaag ggctcaaaga ctaaaattct     3540

tgtgtgaacg caatgacaag gtgttctttg cctctgttcg gtctggtggc agcagtcagg     3600

tttatttcat gaccttaggc aggacttctc ttctgagctg gtagaagcag tgtgatccag     3660

ggattactgg cctccagagt cttcaagatc ctgagaactt ggaattcctt gtaactggag     3720

ctcggagctg caccgagggc aaccaggaca gctgtgtgtg cagacctcat gtgttgggtt     3780

ctctcccctc cttcctgttc ctcttatata ccagtttatc cccattcttt ttttttttct     3840

tactccaaaa taaatcaagg ctgcaatgca gctggtgctg ttcagattct accatcaggt     3900

gctataagtg tttgggattg agcatcatac tggaaagcaa acacctttcc tccagctcca     3960

gaattccttg tctctgaatg actctgtctt gtgggtgtct gacagtggcg acgatgaaca     4020

tgccgttggt tttattggca gtgggcacaa ggaggtgaga agtggtggta aaaggagcgg     4080

agtgctgaag cagagagcag atttaatata gtaacattaa cagtgtattt aattgacatt     4140

tcttttttgt aatgtgacga tatgtggaca aagaagaaga tgcaggttta agaagttaat     4200

atttataaaa tgtgaaagac acagttacta ggataacttt tttgtgggtg gggcttggga     4260

gatggggtgg ggtgggttaa ggggtcccat tttgtttctt tggatttggg gtgggggtcc     4320

tggccaagaa ctcagtcatt tttctgtgta ccaggttgcc taaatcatgt gcagatggtt     4380

ctaaaaaaaa aaaaaaaaaa aaaaaaaaaa ggaaaaaaaa aaagaaaaag aaaacgtgtg     4440

cattttgtat aatggccaga actttgtcgt gtgacagtat tagcactgcc tcagttaaag     4500

gtttaatttt tgtttaaacc tagacgtgca acaaaagttt taccacagtc tgcacttgca     4560

gaagaaagaa aaaaattcaa accacatgtt tatttttttt ttgcctacct cattgttctt     4620

aatgcattga gaggtgattt agtttatatg tttttggaag aaaccattaa tgtttaattt     4680

aatcttaata ccaaaacgac cagattgaag tttgactttt attgtcacaa atcagcaggc     4740

acaagaactg tccatgaaga tgggaaatag ccttaaggct gatgcagttt acttacaagt     4800

ttagaaacca gaatgctttg tttttaccag attcaccatt agaggttgat ggggcaactg     4860

cagcccatga cacaagatct cattgttctc gatgtagagg ggttggtagc agacaggtgg     4920

ttacattaga atagtcacac aaactgttca gtgttgcagg aaccttttct tgggggtggg     4980

ggagtttccc ttttctaaaa atgcaatgca ctaaaactat tttaagaatg tagttaattc     5040

tgcttattca taaagtgggc atcttctgtg ttttaggtgt aatatcgaag tcctggcttt     5100

tctcgttttc tcacttgctc tcttgttctc tgttttttta aaccaatttt actttatgaa     5160

tatattcatg acatttgtaa taaatgtctt gagaaagaat ttgtttcatg gcttcatggt     5220

catcactcaa gctcccgtaa ggatattacc gtctcaggaa aggatcagga ctccatgtca     5280

cagtcctgcc atcttacttt cctcttgtcg agttctgagt ggaaataact gcattatggc     5340

tgctttaacc tcagtcatca aaagaaactt gctgtttttt aggcttgatc tttttccttt     5400

gtggttaatt ttcctgtata ttgtgaaaat gggggatttt ccctctgctc ccacccacct     5460

aaacacagca gccatttgta cctgtttgct tcccatccca cttggcaccc actctgacct     5520

cttgtcagtt tcctgttcct ggttccatct ttttgaaaaa ggccctcctt tgagctacaa     5580

acatctggta agacaagtac atccactcat gaatgcagac acagcagctg gtggttttgt     5640

gtatacctgt aaagacaagc tgagaagctt actttttggg gaagtaaaag aagatggaaa     5700

tggatgtttc atttgtatga gtttggagca gtgctgaagg ccaaagccgc ctactggttt     5760

gtagttaacc tagagaaggt tgaaaaatta atcctacctt taaagggatt tgaggtaggc     5820

tggattccat cgccacagga ctttagttag aattaaattc ctgcttgtaa tttatatcca     5880

tgtttaggct tttcataaga tgaaacatgc cacagtgaac acactcgtgt acatatcaag     5940

agaagaagga aaggcacagg tggagaacag taaaaggtgg gcagatgtct ttgaagaaat     6000

gctcaatgtc tgatgctaag tgggagaagg cagagaacaa aggatgtggc ataatggtct     6060

taacattatc caaagacttg aagctccatg tctgtaagtc aaatgttaca caaaaaaaaa     6120

tgcaaatggt gtttcattgg aattaccaag tgcttagaac ttgctggctt tcccataggt     6180

ggtaaagggg tctgagctca caccgagttg tgcttggctt gcttgtgcag ctccaggcac     6240

ccggtgggca ctctggtggt gtttgtggtg aactgaattg aatccattgt tgggcttaag     6300

ttactgaaat tggaacaccc tttgtccttc tcggcggggg cttcctggtc tgtgctttac     6360

ttggcttttt tccttcccgt cttagcctca cccccttgtc aaccagattg agttgctata     6420

gcttgatgca gggacccagt gaagtttctc cgttaaagat tgggagtcgt cgaaatgttt     6480

agattctttt aggaaaggaa ttattttccc cccttttaca gggtagtaac ttctccacag     6540

aagtgccaat atggcaaaat tacacaagaa aacagtattg caatgacacc attacataag     6600

gaacattgaa ctgttagagg agtgctcttc caaacaaaac aaaaatgtct ctaggtttag     6660

tcagagcttt cacaagtaat aacctttctg tattaaaatc agagtaaccc tttctgtatt     6720

gagtgcagtg ttttttactc ttttctcatg cacatgttac gttggagaaa atgtttacaa     6780

aaatggtttt gttacactaa tgcgcaccac atatttatgg tttattttaa gtgacttttt     6840

atgggttatt taggttttcg tcttagttgt agcacactta ccctaatttt gccaattatt     6900

aatttgctaa atagtaatac aaatgacaaa ctgcattaaa tttactaatt ataaaagctg     6960

caaagcagac tggtggcaag tacacagccc ttttttttgc agtgctaact tgtctactgt     7020

gtattatgaa aattactgtt gtccccccac ccttttttcc ttaaataaag taaaaatgac     7080

acctaaaaaa aaaaaaaaaa aa                                              7102


<210>  92
<211>  7334
<212>  DNA
<213>  homo sapiens

<400>  92
gctcactcgc tcaactcggc gccgccgcgg ccccacgctc cgggcccgtc ctcgaggcgc       60

gcggcgcggg gcgcgggcgc cggggcctga ggcggcgggc gacgcccggg ggcctgacgg      120

ccggccccgc gccatggtgt gagcgccgcc gcccgtgcac gctccgtccg ccctccgcgc      180

ggcccggccg gcagagagcc ccgagcggcc cgagagcgca gccgagcccg ccgccgccgc      240

ccgcggcccc gcgaggagag taccgggccg gctcggctgc cgcgcgagga gcgcggtcgg      300

cggcctggtc tgcggctgag atacacagag cgacagagac atttattgtt atttgttttt      360

tggtggcaaa aagggaaaat ggcgaacgac tcccctgcaa aaagtctggt ggacatcgac      420

ctctcctccc tgcgggatcc tgctgggatt tttgagctgg tggaagtggt tggaaatggc      480

acctatggac aagtctataa gggtcgacat gttaaaacgg gtcagttggc agccatcaaa      540

gttatggatg tcactgagga tgaagaggaa gaaatcaaac tggagataaa tatgctaaag      600

aaatactctc atcacagaaa cattgcaaca tattatggtg ctttcatcaa aaagagccct      660

ccaggacatg atgaccaact ctggcttgtt atggagttct gtggggctgg gtccattaca      720

gaccttgtga agaacaccaa agggaacaca ctcaaagaag actggatcgc ttacatctcc      780

agagaaatcc tgaggggact ggcacatctt cacattcatc atgtgattca ccgggatatc      840

aagggccaga atgtgttgct gactgagaat gcagaggtga aacttgttga ctttggtgtg      900

agtgctcagc tggacaggac tgtggggcgg agaaatacgt tcataggcac tccctactgg      960

atggctcctg aggtcatcgc ctgtgatgag aacccagatg ccacctatga ttacagaagt     1020

gatctttggt cttgtggcat tacagccatt gagatggcag aaggtgctcc ccctctctgt     1080

gacatgcatc caatgagagc actgtttctc attcccagaa accctcctcc ccggctgaag     1140

tcaaaaaaat ggtcgaagaa gttttttagt tttatagaag ggtgcctggt gaagaattac     1200

atgcagcggc cctctacaga gcagcttttg aaacatcctt ttataaggga tcagccaaat     1260

gaaaggcaag ttagaatcca gcttaaggat catatagatc gtaccaggaa gaagagaggc     1320

gagaaagatg aaactgagta tgagtacagt gggagtgagg aagaagagga ggaagtgcct     1380

gaacaggaag gagagccaag ttccattgtg aacgtgcctg gtgagtctac tcttcgccga     1440

gatttcctga gactgcagca ggagaacaag gaacgttccg aggctcttcg gagacaacag     1500

ttactacagg agcaacagct ccgggagcag gaagaatata aaaggcaact gctggcagag     1560

agacagaagc ggattgagca gcagaaagaa cagaggcgac ggctagaaga gcaacaaagg     1620

agagagcggg aagctagaag gcagcaggaa cgtgaacagc gaaggagaga acaagaagaa     1680

aagaggcgtc tagaggagtt ggagagaagg cgcaaagaag aagaggagag gagacgggca     1740

gaagaagaaa agaggagagt tgaaagagaa caggagtata tcaggcgaca gctagaagag     1800

gagcagcggc acttggaagt ccttcagcag cagctgctcc aggagcaggc catgttactg     1860

catgaccata ggaggccgca cccgcagcac tcgcagcagc cgccaccacc gcagcaggaa     1920

aggagcaagc caagcttcca tgctcccgag cccaaagccc actacgagcc tgctgaccga     1980

gcgcgagagg ttcctgtgag aacaacatct cgctcccctg ttctgtcccg tcgagattcc     2040

ccactgcagg gcagtgggca gcagaatagc caggcaggac agagaaactc caccagtatt     2100

gagcccaggc ttctgtggga gagagtggag aagctggtgc ccagacctgg cagtggcagc     2160

tcctcagggt ccagcaactc aggatcccag cccgggtctc accctgggtc tcagagtggc     2220

tccggggaac gcttcagagt gagatcatca tccaagtctg aaggctctcc atctcagcgc     2280

ctggaaaatg cagtgaaaaa acctgaagat aaaaaggaag ttttcagacc cctcaagcct     2340

gctggcgaag tggatctgac cgcactggcc aaagagcttc gagcagtgga agatgtacgg     2400

ccacctcaca aagtaacgga ctactcctca tccagtgagg agtcggggac gacggatgag     2460

gaggacgacg atgtggagca ggaaggggct gacgagtcca cctcaggacc agaggacacc     2520

agagcagcgt catctctgaa tttgagcaat ggtgaaacgg aatctgtgaa aaccatgatt     2580

gtccatgatg atgtagaaag tgagccggcc atgaccccat ccaaggaggg cactctaatc     2640

gtccgccaga ctcagtccgc tagtagcaca ctccagaaac acaaatcttc ctcctccttt     2700

acacctttta tagaccccag attactacag atttctccat ctagcggaac aacagtgaca     2760

tctgtggtgg gattttcctg tgatgggatg agaccagaag ccataaggca agatcctacc     2820

cggaaaggct cagtggtcaa tgtgaatcct accaacacta ggccacagag tgacaccccg     2880

gagattcgta aatacaagaa gaggtttaac tctgagattc tgtgtgctgc cttatgggga     2940

gtgaatttgc tagtgggtac agagagtggc ctgatgctgc tggacagaag tggccaaggg     3000

aaggtctatc ctcttatcaa ccgaagacga tttcaacaaa tggacgtact tgagggcttg     3060

aatgtcttgg tgacaatatc tggcaaaaag gataagttac gtgtctacta tttgtcctgg     3120

ttaagaaata aaatacttca caatgatcca gaagttgaga agaagcaggg atggacaacc     3180

gtaggggatt tggaaggatg tgtacattat aaagttgtaa aatatgaaag aatcaaattt     3240

ctggtgattg ctttgaagag ttctgtggaa gtctatgcgt gggcaccaaa gccatatcac     3300

aaatttatgg cctttaagtc atttggagaa ttggtacata agccattact ggtggatctc     3360

actgttgagg aaggccagag gttgaaagtg atctatggat cctgtgctgg attccatgct     3420

gttgatgtgg attcaggatc agtctatgac atttatctac caacacatgt aagaaagaac     3480

ccacactcta tgatccagtg tagcatcaaa ccccatgcaa tcatcatcct ccccaataca     3540

gatggaatgg agcttctggt gtgctatgaa gatgaggggg tttatgtaaa cacatatgga     3600

aggatcacca aggatgtagt tctacagtgg ggagagatgc ctacatcagt agcatatatt     3660

cgatccaatc agacaatggg ctggggagag aaggccatag agatccgatc tgtggaaact     3720

ggtcacttgg atggtgtgtt catgcacaaa agggctcaaa gactaaaatt cttgtgtgaa     3780

cgcaatgaca aggtgttctt tgcctctgtt cggtctggtg gcagcagtca ggtttatttc     3840

atgaccttag gcaggacttc tcttctgagc tggtagaagc agtgtgatcc agggattact     3900

ggcctccaga gtcttcaaga tcctgagaac ttggaattcc ttgtaactgg agctcggagc     3960

tgcaccgagg gcaaccagga cagctgtgtg tgcagacctc atgtgttggg ttctctcccc     4020

tccttcctgt tcctcttata taccagttta tccccattct tttttttttt cttactccaa     4080

aataaatcaa ggctgcaatg cagctggtgc tgttcagatt ctaccatcag gtgctataag     4140

tgtttgggat tgagcatcat actggaaagc aaacaccttt cctccagctc cagaattcct     4200

tgtctctgaa tgactctgtc ttgtgggtgt ctgacagtgg cgacgatgaa catgccgttg     4260

gttttattgg cagtgggcac aaggaggtga gaagtggtgg taaaaggagc ggagtgctga     4320

agcagagagc agatttaata tagtaacatt aacagtgtat ttaattgaca tttctttttt     4380

gtaatgtgac gatatgtgga caaagaagaa gatgcaggtt taagaagtta atatttataa     4440

aatgtgaaag acacagttac taggataact tttttgtggg tggggcttgg gagatggggt     4500

ggggtgggtt aaggggtccc attttgtttc tttggatttg gggtgggggt cctggccaag     4560

aactcagtca tttttctgtg taccaggttg cctaaatcat gtgcagatgg ttctaaaaaa     4620

aaaaaaaaaa aaaaaaaaaa aaggaaaaaa aaaaagaaaa agaaaacgtg tgcattttgt     4680

ataatggcca gaactttgtc gtgtgacagt attagcactg cctcagttaa aggtttaatt     4740

tttgtttaaa cctagacgtg caacaaaagt tttaccacag tctgcacttg cagaagaaag     4800

aaaaaaattc aaaccacatg tttatttttt ttttgcctac ctcattgttc ttaatgcatt     4860

gagaggtgat ttagtttata tgtttttgga agaaaccatt aatgtttaat ttaatcttaa     4920

taccaaaacg accagattga agtttgactt ttattgtcac aaatcagcag gcacaagaac     4980

tgtccatgaa gatgggaaat agccttaagg ctgatgcagt ttacttacaa gtttagaaac     5040

cagaatgctt tgtttttacc agattcacca ttagaggttg atggggcaac tgcagcccat     5100

gacacaagat ctcattgttc tcgatgtaga ggggttggta gcagacaggt ggttacatta     5160

gaatagtcac acaaactgtt cagtgttgca ggaacctttt cttgggggtg ggggagtttc     5220

ccttttctaa aaatgcaatg cactaaaact attttaagaa tgtagttaat tctgcttatt     5280

cataaagtgg gcatcttctg tgttttaggt gtaatatcga agtcctggct tttctcgttt     5340

tctcacttgc tctcttgttc tctgtttttt taaaccaatt ttactttatg aatatattca     5400

tgacatttgt aataaatgtc ttgagaaaga atttgtttca tggcttcatg gtcatcactc     5460

aagctcccgt aaggatatta ccgtctcagg aaaggatcag gactccatgt cacagtcctg     5520

ccatcttact ttcctcttgt cgagttctga gtggaaataa ctgcattatg gctgctttaa     5580

cctcagtcat caaaagaaac ttgctgtttt ttaggcttga tctttttcct ttgtggttaa     5640

ttttcctgta tattgtgaaa atgggggatt ttccctctgc tcccacccac ctaaacacag     5700

cagccatttg tacctgtttg cttcccatcc cacttggcac ccactctgac ctcttgtcag     5760

tttcctgttc ctggttccat ctttttgaaa aaggccctcc tttgagctac aaacatctgg     5820

taagacaagt acatccactc atgaatgcag acacagcagc tggtggtttt gtgtatacct     5880

gtaaagacaa gctgagaagc ttactttttg gggaagtaaa agaagatgga aatggatgtt     5940

tcatttgtat gagtttggag cagtgctgaa ggccaaagcc gcctactggt ttgtagttaa     6000

cctagagaag gttgaaaaat taatcctacc tttaaaggga tttgaggtag gctggattcc     6060

atcgccacag gactttagtt agaattaaat tcctgcttgt aatttatatc catgtttagg     6120

cttttcataa gatgaaacat gccacagtga acacactcgt gtacatatca agagaagaag     6180

gaaaggcaca ggtggagaac agtaaaaggt gggcagatgt ctttgaagaa atgctcaatg     6240

tctgatgcta agtgggagaa ggcagagaac aaaggatgtg gcataatggt cttaacatta     6300

tccaaagact tgaagctcca tgtctgtaag tcaaatgtta cacaaaaaaa aatgcaaatg     6360

gtgtttcatt ggaattacca agtgcttaga acttgctggc tttcccatag gtggtaaagg     6420

ggtctgagct cacaccgagt tgtgcttggc ttgcttgtgc agctccaggc acccggtggg     6480

cactctggtg gtgtttgtgg tgaactgaat tgaatccatt gttgggctta agttactgaa     6540

attggaacac cctttgtcct tctcggcggg ggcttcctgg tctgtgcttt acttggcttt     6600

tttccttccc gtcttagcct cacccccttg tcaaccagat tgagttgcta tagcttgatg     6660

cagggaccca gtgaagtttc tccgttaaag attgggagtc gtcgaaatgt ttagattctt     6720

ttaggaaagg aattattttc ccccctttta cagggtagta acttctccac agaagtgcca     6780

atatggcaaa attacacaag aaaacagtat tgcaatgaca ccattacata aggaacattg     6840

aactgttaga ggagtgctct tccaaacaaa acaaaaatgt ctctaggttt agtcagagct     6900

ttcacaagta ataacctttc tgtattaaaa tcagagtaac cctttctgta ttgagtgcag     6960

tgttttttac tcttttctca tgcacatgtt acgttggaga aaatgtttac aaaaatggtt     7020

ttgttacact aatgcgcacc acatatttat ggtttatttt aagtgacttt ttatgggtta     7080

tttaggtttt cgtcttagtt gtagcacact taccctaatt ttgccaatta ttaatttgct     7140

aaatagtaat acaaatgaca aactgcatta aatttactaa ttataaaagc tgcaaagcag     7200

actggtggca agtacacagc cctttttttt gcagtgctaa cttgtctact gtgtattatg     7260

aaaattactg ttgtcccccc accctttttt ccttaaataa agtaaaaatg acacctaaaa     7320

aaaaaaaaaa aaaa                                                       7334


<210>  93
<211>  818
<212>  DNA
<213>  homo sapiens

<400>  93
aacctccgtc ccgcagtcca attagcagcc gcgacccggc gcccgcccac gccgcgtcac       60

gagtcagcca aagatggctg cgcccaggta atttgagcaa aggccacagt gaactccggc      120

gtggctgagg aaggaggagg cacccacagg ctgctgggag gagagcataa ggctcaaaat      180

ggaaaatcat aaatccaata ataaggaaaa cataacaatt gttgatatat ccagaaaaat      240

taaccagctt ccagaagcag aaaggaatct acttgaaaat ggatcggttt atgttggatt      300

aaatgctgct ctttgtggcc tcatagcaaa cagtcttttt cgacgcatct tgaatgtgac      360

aaaggctcgc atagctgctg gcttaccaat ggcagggata ccttttctta caacagactt      420

aacttacaga tgttttgtaa gttttccttt gaatacaggt gatttggatt gtgaaacctg      480

taccataaca cggagtggac tgactggtct tgttattggt ggtctatacc ctgttttctt      540

ggctatacct gtaaatggtg gtctagcagc caggtatcaa tcagctctgt taccacacaa      600

agggaacatc ttaagttact ggattagaac ttctaagcct gtctttagaa agatgttatt      660

tcctattttg ctccagacta tgttttcagc ataccttggg tctgaacaat ataaactact      720

tataaaggcc cttcagttat ctgaacctgg caaagaaatt cactgatttt aaacaaatat      780

gtaaacaaaa ataaaatggt aaaaacagtt tatgtcta                              818


<210>  94
<211>  818
<212>  DNA
<213>  homo sapiens

<400>  94
aacctccgtc ccgcagtcca attagcagcc gcgacccggc gcccgcccac gccgcgtcac       60

gagtcagcca aagatggctg cgcccaggta atttgagcaa aggccacagt gaactccggc      120

gtggctgagg aaggaggagg cacccacagg ctgctgggag gagagcataa ggctcaaaat      180

ggaaaatcat aaatccaata ataaggaaaa cataacaatt gttgatatat ccagaaaaat      240

taaccagctt ccagaagcag aaaggaatct acttgaaaat ggatcggttt atgttggatt      300

aaatgctgct ctttgtggcc tcatagcaaa cagtcttttt cgacgcatct tgaatgtgac      360

aaaggctcgc atagctgctg gcttaccaat ggcagggata ccttttctta caacagactt      420

aacttacaga tgttttgtaa gttttccttt gaatacaggt gatttggatt gtgaaacctg      480

taccataaca cggagtggac tgactggtct tgttattggt ggtctatacc ctgttttctt      540

ggctatacct gtaaatggtg gtctagcagc caggtatcaa tcagctctgt taccacacaa      600

agggaacatc ttaagttact ggattagaac ttctaagcct gtctttagaa agatgttatt      660

tcctattttg ctccagacta tgttttcagc ataccttggg tctgaacaat ataaactact      720

tataaaggcc cttcagttat ctgaacctgg caaagaaatt cactgatttt aaacaaatat      780

gtaaacaaaa ataaaatggt aaaaacagtt tatgtcta                              818


<210>  95
<211>  1785
<212>  DNA
<213>  homo sapiens

<400>  95
gtctgacgtc acttccgtcg catttcgggg cggtaccaag atggactcct cgcgggcccg       60

gcagcagctc cggcggcgat tcctcctcct gccggacgcc gaggcccagc tggaccgcga      120

gggtgacgcc gggccgggtg aggcgcgcac caagccgccc cgaggttctc agaggcgagg      180

cgtcggaaaa cggccggcct ccggcagccc tggcccagtc tggaaggact gagtttcggc      240

tttgcaagtc gaatatttaa tgtcagggaa gatccttaga atcgcggagt gctgtgcatc      300

gtcatttcag ctgcgcttca gaattctctg gagagctgat ttgacaccta tttggaaata      360

gcgattaaaa ttaaaaatac ccaccagttt taagtcttaa ggatttacca gaaacatgcg      420

tgtaccgcag tgtacaatga tgtgcgcagt gtttcacttc aggattgctt gtaatagcga      480

attactggaa atatctgcct tgcccgtcag cagaaagctg tttaagtaaa tttgggtata      540

tgtatacctg acacatcagg tcgactcgta tgtaccaatg gggatgattt tcaaagggaa      600

gtgtggaaca ctatggtatg ccgccatttg ggtacaaaac agaaacctcc acagctgttg      660

agaaaaagga gaaacctctt ccaagactta atatccattc tggattctgg attttggcat      720

ccattgttgt gacctattat gttgacttct ttaaaaccct taaagaaaac ttccacacta      780

gcagctggtt tctctgtggc agtgccttgt tgcttgtcag tttatcaatt gcattttact      840

gcatagtcta cctggaatgg tattgtggaa ttggagaata tgatgtcaag tatccagcct      900

tgatacccat taccactgcc tcctttattg cagcaggaat ttgcttcaac attgctttat      960

ggcatgtgtg gtcgtttttc actccattgt tgttgtttac ccagtttatg ggggttgtca     1020

tgtttatcac actccttgga tgatttccga agagacaggg tcttctatgt tgcccaggct     1080

gtctttgaac tcctgggatc aagtgatcct cctgcctcag ccttcgaagt agttgggact     1140

acaggcccac gccaccgtgc ctggctggac atgtaaattt gaagtgaatg gttaaacatc     1200

cagctagctg aaagcatggc agaccctaac agaaaagcta cagtgtgttt ttgcagctat     1260

gaagtgaatg gtttcctggg gaaaattgtg actttgtata actgttgttg aaaccagaat     1320

aaattatatt tcacttgcat atgcataaat tattaaaatt ttcagaagtc agtgatacag     1380

aagtactatt ttgcaatgtt aatctgtttg agtctttgga gaaagtggtt tcattgtagg     1440

tacatagtgc actgttaata ttttaaacaa gtagttcact cttccattta agggatagca     1500

gttccttgta taaaatgact ggatgtgtat aaaggaatta tgttgtcatg tgcctttaac     1560

cagctttagt aattactata atctcatatt tatgatagtt ttgttaggtg acaggaccaa     1620

atgaaaatat tttatgtttt ctcatcactt tagattttat cattatgtac attactgggt     1680

ttttagcatt tcctaatgtg aagttttaat cacttttaag tatacatttt tttctgtatc     1740

atttaaataa aatattttta taactttaaa aaaaaaaaaa aaaaa                     1785


<210>  96
<211>  5740
<212>  DNA
<213>  homo sapiens

<400>  96
cacacacaca cacacacacc acacttgtgc tttcaagaca tcgaaacgga ggctatttcc       60

ctggggaaag aaatcctgcc tggcgagatc tccccattgg ttgtttaccc ggagaaatct      120

acatgtttaa gggggatggt gcatccataa tcagtctgtc cctataggac ttgggtcttg      180

gcgacctttt tgtgacctct cccgccagag gaggctgctg tcactttaaa aatttaaaag      240

aggagcccgt ctggcttccg atcagatcac tctgggcggc gggagatagc tccctttctc      300

cctcgccccg ggttctttct ggatggccga gcagatcctc tttaaagaga cagttcatga      360

aatagaaacc cggcggctga gcttggagtt gcgaaagggg acgatcccgt gagggtccag      420

gacccgcgaa ggcgctgcgg aggatctgaa agggggatag agctcccctc gcctccccag      480

gccccccacc ttttcaaact ctcctcctcc tgcttgtttt cccccattgg aactgggaag      540

gagaagtaga agttttagtg ggtttcagat aactttcatt acacatcggg ctgataagag      600

caagagaaag tgagaaaaga gggaggtgat gtgaaccaga aggaatagct ccgagctcat      660

ttaggaaggg ggaaaaagcc aaaacacacc aaacccgggt cacccagacg aaagaagact      720

tcatttcttg tattaaaaat acactgttgg cggacaataa atccgaaacg cgtggtcctg      780

gagagcagat cctagagacg gacaaagttg tcagagaccc atttggaaat cgagacgcga      840

ggcttttaaa aaattattat tattattttt aaacatctct aaatgttgct cgggatcgtt      900

tgaaaggatt ttcgtgcagg agcgttgggg gctgctgatt attttatttt gtttattttg      960

attcttctgt gaatgcctat tattgctgag ttgaggccat agaaatctaa agatcttaga     1020

cgaattttac aatgtgaagt tctgcataga tgccagtcaa ccagatgttg gaagctggct     1080

caagtacatt agattcgctg gctgttatga tcagcacaac cttgttgcat gccagataaa     1140

tgatcagata ttctatagag tagttgcaga cattgcgccg ggagaggagc ttctgctgtt     1200

catgaagagc gaagactatc cccatgaaac tatggcgccg gatatccacg aagaacggca     1260

atatcgctgc gaagactgtg accagctctt tgaatctaag gctgaactag cagatcacca     1320

aaagtttcca tgcagtactc ctcactcagc attttcaatg gttgaagagg actttcagca     1380

aaaactcgaa agcgagaatg atctccaaga gatacacacg atccaggagt gtaaggaatg     1440

tgaccaagtt tttcctgatt tgcaaagcct ggagaaacac atgctgtcac atactgaaga     1500

gagggaatac aagtgtgatc agtgtcccaa ggcatttaac tggaagtcca atttaattcg     1560

ccaccagatg tcacatgaca gtggaaagca ctatgaatgt gaaaactgtg ccaaggtttt     1620

cacggaccct agcaaccttc agcggcacat tcgctctcag catgtcggtg cccgggccca     1680

tgcatgcccg gagtgtggca aaacgtttgc cacttcgtcg ggcctcaaac aacacaagca     1740

catccacagc agtgtgaagc cctttatctg tgaggtctgc cataaatcct atactcagtt     1800

ttcaaacctt tgccgtcata agcgcatgca tgctgattgc agaacccaaa tcaagtgcaa     1860

agactgtgga caaatgttca gcactacgtc ttccttaaat aaacacagga ggttttgtga     1920

gggcaagaac cattttgcgg caggtggatt ttttggccaa ggcatttcac ttcctggaac     1980

cccagctatg gataaaacgt ccatggttaa tatgagtcat gccaacccgg gccttgctga     2040

ctattttggc gccaataggc atcctgctgg tcttaccttt ccaacagctc ctggattttc     2100

ttttagcttc cctggtctgt ttccttccgg cttgtaccac aggcctcctt tgatacctgc     2160

tagttctcct gttaaaggac tatcaagtac tgaacagaca aacaaaagtc aaagtcccct     2220

catgacacat cctcagatac tgccagctac acaggatatt ttgaaggcac tatctaaaca     2280

cccatctgta ggggacaata agccagtgga gctccagccc gagaggtcct ctgaagagag     2340

gccctttgag aaaatcagtg accagtcaga gagtagtgac cttgatgatg tcagtacacc     2400

aagtggcagt gacctggaaa caacctcggg ctctgatctg gaaagtgaca ttgaaagtga     2460

taaagagaaa tttaaagaaa atggtaaaat gttcaaagac aaagtaagcc ctcttcagaa     2520

tctggcttca ataaataata agaaagaata cagcaatcat tccattttct caccatcttt     2580

agaggagcag actgcggtgt caggagctgt gaatgattct ataaaggcta ttgcttctat     2640

tgctgaaaaa tactttggtt caacaggact ggtggggctg caagacaaaa aagttggagc     2700

tttaccttac ccttccatgt ttcccctccc attttttcca gcattctctc aatcaatgta     2760

cccatttcct gatagagact tgagatcgtt acctttgaaa atggaacccc aatcaccagg     2820

tgaagtaaag aaactgcaga agggcagctc tgagtccccc tttgatctca ccactaagcg     2880

aaaggatgag aagcccttga ctccagtccc ctccaagcct ccagtgacac ctgccacaag     2940

ccaagaccag cccctggatc taagtatggg cagtaggagt agagccagtg ggacaaagct     3000

gactgagcct cgaaaaaacc acgtgtttgg gggaaaaaaa ggaagcaacg tcgaatcaag     3060

acctgcttca gatggttcct tgcagcatgc aagacccact cctttcttta tggaccctat     3120

ttacagagta gagaaaagaa aactaactga cccacttgaa gctttaaaag agaaatactt     3180

gaggccttct ccaggattct tgtttcaccc acaaatgtca gctattgaaa acatggcaga     3240

aaagctagag agcttcagtg ccctgaaacc tgaggccagt gagctcttac agtcagtgcc     3300

ctctatgttc aacttcaggg cgcctcccaa tgccctgcca gagaaccttc tgcggaaggg     3360

aaaggagcgc tatacctgca gatactgtgg caagattttt ccaaggtctg caaacctaac     3420

acggcacttg agaacccaca caggagagca gccttacaga tgcaaatact gtgacagatc     3480

atttagcata tcttctaact tgcaaaggca tgttcgcaac atccacaata aagagaagcc     3540

atttaagtgt cacttatgtg ataggtgttt tggtcaacaa accaatttag acagacacct     3600

aaagaaacat gagaatggga acatgtccgg tacagcaaca tcgtcgcctc attctgaact     3660

ggaaagtaca ggtgcgattc tggatgacaa agaagatgct tacttcacag aaattcgaaa     3720

tttcattggg aacagcaacc atggcagcca atctcccagg aatgtggagg agagaatgaa     3780

tggcagtcat tttaaagatg aaaaggcttt ggtgaccagt caaaattcag acttgctgga     3840

tgatgaagaa gttgaagatg aggtgttgtt agatgaggag gatgaagaca atgatattac     3900

tggaaaaaca ggaaaggaac cagtgacaag taatttacat gaaggaaacc ctgaggatga     3960

ctatgaagaa accagtgccc tggagatgag ttgcaagaca tccccagtga ggtataaaga     4020

ggaagaatat aaaagtggac tttctgctct agatcatata aggcacttca cagatagcct     4080

caaaatgagg aaaatggaag ataatcaata ttctgaagct gagctgtctt cttttagtac     4140

ttcccatgtg ccagaggaac ttaagcagcc gttacacaga aagtccaaat cgcaggcata     4200

tgctatgatg ctgtcactgt ctgacaagga gtccctccat tctacatccc acagttcttc     4260

caacgtgtgg cacagtatgg ccagggctgc ggcggaatcc agtgctatcc agtccataag     4320

ccacgtatga cgttatcaag gttgaccaga gtgggaccaa gtccaacagt agcatggctc     4380

tttcatatag gactatttac aagactgctg agcagaatgc cttataaacc tgcagggtca     4440

ctcatctaaa gtctagtgac cttaaactga atgatttaaa aaagaaaaga aagaaaaaag     4500

aaactattta ttctcgatat tttgttttgc acagcaaagg cagctgctga cttctggaag     4560

atcaatcaat gcgacttaaa gtgattcagt gaaaacaaaa aacttggtgg gctgaaggca     4620

tcttccagtt taccccacct tagggtatgg gtgggtgaga agggcagttg agatggcagc     4680

attgatatga atgaacactc catagaaact gaattctctt ttgtacaaga tcacctgaca     4740

tgattgggaa cagttgcttt taattacaga tttaattttt ttcttcgtta aagttttatg     4800

taatttaacc ctttgaagac agaagtagtt ggatgaaatg cacagtcaat tattatagaa     4860

actgataaca gggagtactt gttccccctt ttgccttctt aagtacattg tttaaaacta     4920

gggaaaaagg gtatgtgtat attgtaaact atggatgtta acactcaaag aggttaagtc     4980

agtgaagtaa cctattcatc accagtaccg ctgtaccact aataaattgt ttgccaaatc     5040

cttgtaataa catcttaatt ttagacaatc atgtcactgt ttttaatgtt tatttttttg     5100

tgtgtgttgc gtgtatcatg tatttatttg ttggcaaact attgtttgtt gattaaaata     5160

gcactgttcc agtcagccac tactttatga cgtctgaggc acaccccttt ccgaatttca     5220

aggaccaagg tgacccgacc tgtgtatgag agtgccaaat ggtgtttggc ttttcttaac     5280

attccttttt gtttgtttgt tttgttttcc ttcttaatga actaaatacg aatagatgca     5340

acttagtttt tgtaatactg aaatcgattc aattgtataa acgattataa tttctttcat     5400

ggaagcatga ttcttctgat taaaaactgt actccatatt ttatgctggt tgtctgcaag     5460

cttgtgcgat gttatgttca tgttaatcct atttgtaaaa tgaagtgttc ccaaccttat     5520

gttaaaagag agaagtaaat aacagactgt attcagttat tttgcccttt attgaggaac     5580

cagatttgtt ttctttttgt ttgtaatctc attttgaaat aatcagcaag ttgaggtact     5640

ttcttcaaat gctttgtaca atataaactg ttatgccttt cagtgcatta ctatgggagg     5700

agcaactaaa aaataaagac ttacaaaaag gagtattttt                           5740


<210>  97
<211>  6092
<212>  DNA
<213>  homo sapiens

<400>  97
gagtgttttc agaagtggga atagcaggcg aggtcttgag gcctgaagaa gcaaagcgtc       60

gcttagtcaa tgctgagatg cgtcttgtgg aacagaattt ttgggacatt tgcaggatga      120

gttagatgaa ctccgtgctg agatggaaga gatgagagac agttatttag aggaagatgt      180

ttaccagctg caggaacttc ggcgagaact ggaccgcgct aataaaaact gccgaatcct      240

gcagtaccgt cttcggaaag ccgagcagaa aagcctgaaa gtggctgaga cgggtcaggt      300

ggatggtgag cttattcgaa gcctggagca ggacttgaag gtagccaaag atgtatctgt      360

cagattgcac cacgaactta agacggtgga ggaaaagcgc gctaaagctg aggatgaaaa      420

cgaaactctc cgacagcaga tgattgaagt ggaaatatcc aaacaggccc tccagaatga      480

gctggagaga ctgaaagaga gttccctaaa aagaagaagc actcgggaaa tgtacaagga      540

gaagaaaacc tttaaccagg atgacagtgc cgatttgagg tgccagctcc agtttgccaa      600

agaggaagcc ttcctgatgc gcaaaaagat ggccaagcta ggaagggaga aggacgagct      660

ggagcaggag ctccagaagt acaagtccct ctatggggat gtggacagtc ccctgcccac      720

gggggaagca ggcgggcccc ccagcacccg ggaggccgag ctgaagctgc ggctaaagct      780

ggtggaggag gaagccaaca tcttgggccg gaagatcgtg gagctggagg tggagaaccg      840

tggcctcaag gcagagatgg aggacatgcg gggccagcag gagcgggagg gcccgggtcg      900

ggaccacgca cccagcattc ctacctcacc cttcggtgac tccctggagt cctccactga      960

gctccgccgc cacctgcagt ttgtagaaga ggaagcggag ttgctccgga ggtccatctc     1020

cgagatcgaa gaccacaacc ggcaactgac ccacgagctc agcaagttta agtttgagcc     1080

tccccgggag ccgggctggc taggagaggg tgcaagtcct ggtgccgggg gtggggcccc     1140

cctgcaggag gagctgaagt cagccaggct gcagatcagc gagctcagcg gcaaggtgct     1200

caaactgcag cacgagaacc acgcgctgct gtccaacatc cagcgctgcg acctggcagc     1260

ccacctgggg ctgcgtgccc ccagtccccg ggacagcgat gccgagagtg atgcgggcaa     1320

gaaggagagt gatggggagg agagccgcct gccccagccc aagcgggaag ggcctgttgg     1380

cggggagagt gactcggagg aaatgtttga gaagacgtcg ggcttcggga gcgggaagcc     1440

atcggaggcc agcgagccat gccccacgga gctcctgaag gcccgggagg actctgagta     1500

cctagtgacc ctaaaacacg aggcccagcg gctagagcgg acggtggagc gcctcatcac     1560

ggacaccgac agcttcctcc atgatgcggg gctgcggggt ggtgcgccct taccggggcc     1620

tggcctccag ggcgaagagg agcagggtga gggggaccag caggagcccc agctgctggg     1680

gaccatcaac gccaagatga aggctttcaa gaaagagctg caggccttcc tggagcaggt     1740

gaaccgcatt ggggatggcc tatccccctt gccccacctc acagagtcct ctagcttcct     1800

ctccactgtg acttccgtgt cccgggactc ccccatcggg aacctgggga aggagctggg     1860

cccagacttg cagtccagac tgaaagagca gctggagtgg cagctcgggc cggcccgagg     1920

ggacgagcgg gagagcctgc gcctccgagc cgcgcgggag ctgcaccgcc gcgcagacgg     1980

ggacaccggg agccacgggc tgggaggcca gacctgcttc agcctggagc tcaggggccc     2040

ccccgtttta cctgagcaga gtgtatccat agaggagcta cagggtcagc tcgtgcaggc     2100

ggccagactg catcaagagg agacagagac atttacaaac aagatccata agatggagga     2160

ggagcacctc tatgccttga ggtggaaaga actggaaatg cacagcctgg ctttgcaaaa     2220

caccctccat gagcgaacct ggagtgatga gaagaatctg atgcagcagg agctccggtc     2280

cttgaagcag aacattttcc tcttctacgt caaactcagg tggctgctga aacactggcg     2340

gcaagggaag cagatggagg aggaaggaga ggagttcact gagggtgaac atccagagac     2400

cctctccagg ctcggggagc ttggagtcca ggggggtcac caggcggatg gcccagacca     2460

cgacagtgac cgaggctgtg gctttccagt gggggagcac tccccacact cccgggtgca     2520

gattggagat cacagcttgc ggctgcagac cgcggacagg ggacagcccc acaaacaggt     2580

ggtggaaaac cagcagctgt tcagcgcctt caaggccttg ctggaggact tccgtgcgga     2640

gctgcgggag gatgagcgtg cccgactacg gctgcagcag caatatgcca gcgacaaggc     2700

ggcctgggac gtggagtggg ccgtgctcaa gtgccgtctg gaacagctgg aagagaagac     2760

tgagaacaag ttgggagaac taggctcctc cgctgagagc aagggggcct tgaagaagga     2820

gagagaggtg caccagaagc tcctggcaga cagtcacagc ctggtcatgg acctgcgctg     2880

gcagatccat cacagcgaga agaactggaa ccgggagaag gtggaacttc tcgaccgcct     2940

ggacagagat cggcaggagt gggagcggca gaagaaggaa ttcttgtgga ggatagagca     3000

gttgcagaaa gagaacagtc cccggagagg tggcagtttc ctctgtgatc aaaaagacgg     3060

caacgttcgc ccctttcccc accagggaag cctccgcatg ccccgtccag tggccatgtg     3120

gccttgtgca gatgctgact ccatcccgtt tgaagaccgg ccgctgtcca agctgaagga     3180

gtcggacagg tgctcggcca gtgagaatct ctacctggat gccttgtccc tggatgacga     3240

gccagaagag ccaccagccc acaggcccga gagggagttc aggaaccgcc tccctgagga     3300

agaagaaaat cacaaaggaa atcttcaaag ggcggtgtcc gtgtcctcca tgtctgagtt     3360

ccagcgtcta atggacatct cccccttcct gcctgagaag ggcctgccgt ccaccagcag     3420

caaggaggat gtcaccccac ccctgtctcc agacgacctc aagtacatcg aggagttcaa     3480

caagagctgg gactacacac ccaacagggg ccacaatggt ggggggccgg acctttgggc     3540

cgacaggacc gaggtggggc gggcagggca cgaggacagc acagagcctt tccccgactc     3600

ctcctggtac ctaaccacaa gtgtcaccat gaccacggac accatgacca gcccagagca     3660

ctgccagaag cagccactgc ggagccacgt cctcaccgag cagtcggggt tgcgcgtgtt     3720

acacagcccg cctgccgtgc gcagggtcga cagcatcacg gcggcaggtg gtgagggtcc     3780

ctttcccaca agcagagcca gagggagccc gggagacacc aagggaggcc ctccagaacc     3840

catgctcagc aggtggcctt gcacctcccc caggcactcc cgggactatg tggagggggc     3900

acggcgcccc cttgatagtc ccctctgtac ctccctgggg tttgcctccc cactgcacag     3960

cctggagatg tccaagaact tgagtgatga catgaaggag gtggccttct ctgtcaggaa     4020

tgccatctgc tccggccctg gcgagctgca agtcaaggac atggcctgcc agaccaatgg     4080

gtcccggacg atggggaccc agactgttca gaccatcagt gtgggcttgc agactgaagc     4140

cctgcgtggc agcggtgtca ccagcagccc ccacaagtgt ctcactccaa aggctggggg     4200

cggtgctaca cccgtgtcgt ctccttcccg gagccttagg agcagacagg tggcccctgc     4260

catcgagaag gtgcaggcca agtttgaacg cacatgctgc tcccccaagt atggttctcc     4320

caagctgcag aggaagcccc tccccaaagc cgaccagcca aataacagga cgtcaccagg     4380

gatggcccag aaagggtaca gtgagtcagc ctgggcccgc tccaccacca caagggagag     4440

ccccgtgcac accaccatta atgatggcct ctccagcctc ttcaacatca ttgaccacag     4500

ccccgtggtg caggacccct tccagaaggg gctgcgggcc ggcagtcggt ctcgctcagc     4560

agagccccga ccagagctgg gcccaggcca ggaaacaggc accaattccc gaggaaggtc     4620

gcctagcccc attggggtgg ggtcagagat gtgcagggag gaagggggag agggcacgcc     4680

agtgaagcag gacttatctg ctccccctgg ctacacgctc actgagaacg tggcccggat     4740

cctcaacaag aagctgctgg aacatgcctt aaaggaggag aggaggcagg ctgcccacgg     4800

gcccccgggt ctccacagtg acagccactc gctgggggac acagccgagc cagggcccat     4860

ggagaaccaa actgtcttgc taactgcccc ctggggactc tagccctgcc cgcctcacgc     4920

tgaactacct tgttctgcac tagctccatc cctagagccc tgcttctcca ggcccgagag     4980

accagcaaac cgtcgccctc cgtcccgttg ggccccacat tcccccactg cctcacagcc     5040

tcagtcaccc ggagacccga cgtccttgga ggagcatggt ggcgaggagc cgcccgagga     5100

gcagccacac cgagatgcaa gcttgcatgg attatcacag tataattcac tgtaatttgc     5160

ataaccacac catcaccatg aacaaaactc tgcccaacag gagagatcta gttttctcaa     5220

ggtcaaagaa tgttttttaa aaacacaaag ctgctgaatg ttcaacctgt gaaactgaga     5280

tgtttctaga atgaaacagt aaatgtgcct gtaataactt aatttttttc atagctcaga     5340

aaactatttt tgtctccatc ttttttacac acagtatatt aaacgaaaag gtaaataagg     5400

tataaataga tttaaaaaat aaaagtttta aaaaatgtac attttaagag attctgaaca     5460

ccctcgctgt caatacctga ctgcctctgt taaatttgca ctgttacatt ttggttcagt     5520

ttatttccat gttgaattag agtggattaa gttaatttta ttttgtcagt gttactgttt     5580

tttacgaatt ttttaatgct tcagactgtc tgattcagtg aactttttgt agtgaaaaag     5640

ccatgaagcc agtagacaag acagatattc tgtatgctgg aggggataca ggatgatttt     5700

gaaaaggtac aaagtcctca gtgggcttag aaaattcact gtatgatcct tatattatcc     5760

tacttggctt gcacgtcttc gggtgcatgt atataccgct actgtgtcct cgccatcacc     5820

taaatgtgac tcagtctgtt ccactgtaat atgttgtgaa tttccttgta ctgtactttt     5880

attgttggtc ttcttgcatc gatgatccaa cagcaacacc atttttaaat tattgtgaaa     5940

agattaactg gcaatgtaca gagtttactc aaagttttct taagggaaaa cactacaaaa     6000

agtcacaagg ataccaaatg gaaacacatg atgatgcctc tgggtctgta tgagaccgtg     6060

atgaagtaga aataaagccc ttctgagatg gc                                   6092


<210>  98
<211>  7477
<212>  DNA
<213>  homo sapiens

<400>  98
atgtggccgg ccggcgcggg caccaagctg ccctgtcccc gagactctgc gctccggcgg       60

gcggctttct ctgggaacct cacggccctg ccctctcacc tcgtgcccgc cggccgcagc      120

gtccgggtct tcatcagcgc caaccctgaa gatacgggag cagaaagaca ggcgctaaga      180

gaaaatgtat atcctaaact gagagaattc tgcagagaaa actatggatt ggaatttcag      240

gtcatagatc tgtactgggg agtggaagaa gatgagtggg acagcccaga gctccagaag      300

acccgcatga agctgctgga gaattgcttg aaaacttctg caggtccatg ttttgttgga      360

ctattaggtg aaaaatatgg gaatatccga atccctggag aagttgaagc ctcagagttt      420

gaaatgattt tggatgccgc catagaggca aagctggaga ccaagttgct ggaggagtgg      480

tactgtcgag atgagaactc ggtgccagca gcctattacc tcagacccaa gtcagaaatg      540

ctgagaagca atagaaatgc aatgcagcct tctaccaatg ctgaaaacga gaagacatgg      600

caagagatat cagatgagat caagaagata tttaaggctg ctgtaaagct gttacacgaa      660

aagggtaaaa tgaaacacag ccaggctaag aggtacctgt tctcagctat agaggatgag      720

tttgactttg ctctgggaaa acaaactcca gcatttctaa agaagtgtgt ttgctacatt      780

aggaaaattg ctaacattga gcgctttgtg aaaatcccag agatgggaaa atacatggat      840

ataactggaa cagaaccgag gattattcgg gacccagaag cccaagagaa gctgataaaa      900

ctcagggatg aatttattcc tactattgtt gcatcatcta atctgagagt gtacacatct      960

gttactcatt gtgacatgaa actaggctac tcccaagaaa tagaaaatca ttacatcgaa     1020

ggacttggta aacaatttta tgaggacatg attgatataa ttcaggcaac gatacaacag     1080

aattttgaca ctgaaactga tacactctat gatgaaatcc ttcaacattc atcattatgt     1140

aaaacatacg cctccttcta tgagtacaaa tgtgaatctc taaacatagt gcataactac     1200

attcttccaa gcaaagctgg acacatcaac cctcttatta tatatggtgg gccatgcact     1260

gggaagaccc ttctgctagc tgaagtagca aagaaggctt atggctggct acatgaggac     1320

acaggaccag aatctgaccc agtagtcatc gtgagatttc taggaacgac agacatgagc     1380

tctgacctta ggactctcct tctaagtgtt tgtgaacaat tggcagttaa ctaccggtgt     1440

ctggttcaaa gctaccctaa gaagatccat gacctctgtg acttatttat aaatcttttg     1500

aatgagtctt cactgcagag acctctagtc ataatattcg atgcactaga gcagctctca     1560

gagaatgatg atgccaggaa gctttggtgg ctcccagctc acctgccccg ctttgtccgg     1620

atagtccttt ccacgctgcc caacaaacat gggatcttgc agaaactaag gtgccttatc     1680

catgaagaag acaactacat cgagctgatt ccccgagaca ggaagatgtg cagccaggtc     1740

ctcaaacacc agctgctgcg cgtcaaaagg aaggtcacat caggccagca gatttatgtg     1800

aacaatgcat tatccaagtg cacactgcca atgtttgtga acctgacctt cagggaggtg     1860

aggcactgga gatctcacaa agacgtcgat gaatcctccc tctctgtcac cgttcatgaa     1920

agtatagagc agttattctg gtccttggag aagaagtgtg gtcagaaact ggtctctagg     1980

gctcttggtt acatcaccat ggccaaaatg ggtctgagtg aaatggaact ggaggatgtg     2040

ttagccctag acaacagtgt aatgagtgag ctcaaagaaa acaccagacc cagcaatccc     2100

ctgagagtac cttacttgta cattgcaagg ctcaaggagg gtctcagtgg atacctaata     2160

gaaagacatg tgaaaaatgt cacactccta gtctgggcca acagacacct gcagctcata     2220

gcccagaagc tatatctgca ggatgacaat gacctgcgtg aaatgcacac catcttagca     2280

gattattttc tgggggtttg gtcagggggc aggaggaaag ccttctgcct tgaggacccc     2340

tacttgaatg gctgccttga cttggagaac agaagtttgc tggaggaaga aaagcacttc     2400

atggaacagg cttcctttga caggcaggct ccagaccagc cctgggtttt ccagtgtaat     2460

cccctggaac ctgacatctt tttcgttaat catcggaaaa tgtctgagct gttgtaccac     2520

ttgacgaggt gtggaaaaac cgatgacctg ctttacggca tcatcatgaa cttcagctgg     2580

ctttatacca tgatcaaaat tggccagttt gacaaagtgc tttcagacat tgagctggct     2640

tacaactact cgcaagagaa ggagctgaag ttcctggcca acaccctccg cagcatcaaa     2700

aacaaggtca ctgcatttcc cggctccctt tcagcagagc ttcagcaaag actgctgcct     2760

gttgtaagct ccctgcccaa acttagacat cttcttttag agtgtgataa agatgggccc     2820

aaatattgct ccattgtacc actgcattca tccatggatg tgacatacag cccagagcgt     2880

cttcccttat catccagtca cctgcatgtc acagagatcc tgcctacctg taaccccagc     2940

actgtcctca cagctttaga aaatggttcc atcagcacct gggatgtaga gactcgacag     3000

ctactcaggc aaatcaccac agcccagtct gtcatcctgg gcatgaaact caccagtgat     3060

gaaaagtacc ttgtggtggc tacaacaaat aacaccttgt tgatttatga caatgtcaat     3120

tcttgcctcc tgtctgaagt agaaatcaag gggaccaagc atggaagcag cgccacctac     3180

atcaatggat ttacactgtc cgccaaccac gcccttgcat ggctcgaagc cagcaaagat     3240

gtcactgtca tcgatctgct gtacggatgg ccgctttacc agttccactg ctggtatgaa     3300

gtgacgtgcg tccagtgctc cctggatggt ctgtatgctt tctgtggcca atacctgaac     3360

acaaccacca tatttcattt agggagtgga gaaaagttat gtacagtgac atcagaattt     3420

tcaggtggat ttgtgaagtt tcttcttatc ttggacacag ctcaggaaat ggtcatggta     3480

gacagtgaag gaagtctttc tgtttggaat actgaggaca tttccagccc ccagctgact     3540

gatgactttg attgccgaag agaagacagt gaggtggtca gcattgagct ttcagaagac     3600

caaagtgcag ttctgatctg taaagccctc agcattgagc tcttagatac tggtctgtgg     3660

aaggtggctg aaaagttcag agccaagcac aacgaacgct ttatatctgc cgtgctgtct     3720

aaaaatggag attgtatcat cgccaccatg gaaaatacct cagctgtgtt tttttggagg     3780

cgggacacag gacagtgtat ggcaagcttg caggaaatct caggttccat tgttaagtta     3840

gtgaaatcca gtcaccacaa tatgctactg tctttatcaa ccagtggtgt tctttccatt     3900

tgggacatag atataatcac agctatgtcc aacatagata agactggaaa acccatccaa     3960

agtctgttgt tgcctgctag aggggaaatc atttactccc tggatggatc cgattgtgtt     4020

cataagtgga acttcagcag tggcttcatc gaagcagtat tcaagcatga aggaatagtt     4080

gaacactgtg tgttaacatc caccggagat ataatggtga catcagatga caaaagcagc     4140

cagtatgtct ggcacaccag cagtggtgaa aacctttttc gaattaacgg gcagagaata     4200

tctcagctgc tgattacaca caatgaccag tttgtggtct cgctctgtga ggaaaatgcc     4260

tccagggttt ggaggctcgc cacaggccac agggtctgca acattctgac cactttgcag     4320

aatgccttta ttacctccgc aaataccttc gtggtgggaa tgactaaaag caaagtgttg     4380

gcagtcagtc tttggacagg aagtatcacc aagaaatttt gctgtgaaga tgggaccacc     4440

atcgtgaatt ttaaattaat ccctgactgt cctgatatca tcgtgtttat cacatcggcc     4500

gagactgtga acatctggag tctgacagat gaagtgatct gtcggcgcgt gcaacttcca     4560

aacaacttct tgaaaaatct ggaggacttt gaaatttctc ccaatggaaa gctaggcatt     4620

atagccaggg gagatgaaaa catcaatgtg ctagatttat acagtggtaa attgcgggtg     4680

gttcacgcct ctgggatcat ctggcggcag aggttgtctc gggatggtcg ctacctggta     4740

tacatttgtt tccgaaatgg ggaggaggag gatgaaaatg gtgcaatatt cagtttaatt     4800

gtaatgagac tggcagatgg caaaaatatc ggtgcttgtt ccctttacaa aacaccaact     4860

ttccttgcac tctcccagag gcacctgaac atcattgtgg gctttgatga tgggagtata     4920

gggatctaca cggtagtaga ccgtgtagat gctgcactga aaatcaaaat tgccacttca     4980

aatagcagac aaattttcaa caatgcaaca cacacctcca ggccaaagtg taacagttat     5040

tgttttaaaa tatctgtgga ttgcttatgg agagagtcca ctgaggtctt tgcaagagac     5100

agccccatca cagttagtga ctctactgag tccaatgaag caacaccctc caagaaacac     5160

aactcttgtt atgagcgggt atgctcggcc ctagaagcca ggggccacag ctatgcccct     5220

gataactgac aaaatgtttt ccagctaagc agaaatatgt gatccacgta cagaagggaa     5280

aaaaatgtgc cccaaatgat aaactattca tttattaaaa ggcaggagcg atgctggaat     5340

tccagtgttt tattaagatg ttcatgaaat ggacaaatag gttagtcttg ggtgtggtct     5400

ttttgtcaaa gtgtatccag aatgtcagaa tttctagtag taatatttaa atggttactt     5460

catctgaaag gcagaggcta aaagttttta aattagctgt gtggtgaggc agcataatac     5520

atcccactgg ttaagatgag agaggctaga gttatataca gatcatttgg atgggaatta     5580

gttctacaaa aatcagctga aatcatgaag acaaagagct gcttgacttc aaatgattgt     5640

gtgataagta aacacagcct taatctctct ttacatttta cagtcctgac aactgtgtac     5700

acctagtctg cagtgaacgg tctaaaggtg caaaatatgt aacaaaaata cccaagtgta     5760

ttcccagttt cccgagagat atgacctgaa acatgagact gtggactgga ctgggacaag     5820

aactaactac cactatcata gggctactga acatggagag tcagtcttta ttaaaagaca     5880

gttgcaacaa ttgcatgcga gggtttctgt ataacagaat atatgatttt taaactattt     5940

cctgggttgc aaaagaacac atttagtaag aaacaacaat cttttcgcat ctttttgaaa     6000

tgcatatttg tgctgggtgt aaagaagatt acaggaaggg cattacaaat ctggtcaaaa     6060

cacctgtcca tttccatcat tgtactaaca gaagtctgta ctatttggtc agtttgtatg     6120

gaagcataaa tattccctaa attcctgcag ttagtcttca tagaaagcaa gctttctcaa     6180

catgccatct ctgagatact gatgacgttt gccttactca cattccttct ctttcctgtg     6240

taaaatgcag atagatgacc aaatactctg ggataaactg aatatgcctg tctttgtgct     6300

aaaatattcc ataaatctta agggtgtcca aaagttcttt attgtccttg tttgtaatca     6360

ctttcttact tctacacacc atctgtatgc ttctttatct gttactcttc ctgattgagg     6420

actcttctga gccttttata gtcctatcca tttcaaagca gaagctgtgg aatggtatta     6480

aatatttttt aaaattaatt cacctgttta aaagaaaaca ttgcatctca aaaggtgaag     6540

atgattgttc tttcttccat atcctcctta cggcatgtcc ttggataact tttcaaaagg     6600

tatccacact tttggttgag tttagttttc ttagaaagta gagaagtaac actttactag     6660

aataatgaac aaggaattga tttgctctag gcccagctct gccataaact cattgtgtat     6720

tcctagacag gtctttaact tcatcagtgt gttgtttttg tgaagtgcaa aataaagata     6780

gtgatagttt ctgctgtagc cctcataggg acattgggaa gcagtataag aaaaacttca     6840

gcaacatcat gattattgat gctaatagga aaaataaatt catgtaaccc atagagaatc     6900

caggtcaatt gtatttcctc ttggaaagca gtttaacatg taagcgttca aagatgtgat     6960

tcagataaaa atacccaggt ccatagtgaa agatgttttt cagtatgtta cttatggttt     7020

agctactagc cagggaggtg gtagcccaga gaaggcaaac cacatacaga tcacctggag     7080

ttgattatat gagtctatgc ttttgagctc tttaggcaac acattctcat tcctgtcatt     7140

atcagttgaa cctccatgcc acacatttct aagaattaaa tgcctagatg gattaaatgt     7200

agtatgtgaa tgttctatgt aaaagccaat agagtataca agtgacttga atgatttttc     7260

ctaacttgtt tgcaactgat agctcatatt gaatgttttt atgtaaactt tgtatcgttg     7320

ggaagaatta cccaatcaga gatttatatt ttcataaatg ttacatttag ttaaattttg     7380

ttacagagtt gttacactag aaaattattt cagtcttcaa acaatataca gtcttgtgta     7440

tgtattattt gtatgaataa aagataaact acttaga                              7477


<210>  99
<211>  2723
<212>  DNA
<213>  homo sapiens

<400>  99
gggcggggcg caggagcccc ggggcggagg agccggggag gcgggaggcg ggaggcggga       60

ggtgttgggg ccgttgaagc ggcctccctc ccgcccccag ccgcccggtc tggccccagc      120

cctgtcccga cccccggcct ggcccactcc gaccctaccc ggccgaaggg ttccgctgga      180

cacgcaggcg gcctccggag cagcccaagc ccatgagggc cgcgcgcccg gccgccggtg      240

ctgacgagac ggagctcctg gcccccgagg aggagcagag gatcaatgcg gttcaagaat      300

cgattccagc ggttcatgaa ccatcgagct ccagccaatg gccgctacaa gccaacttgc      360

tatgaacatg ctgctaactg ttacacacac gcattcctca ttgttccggc catcgtgggc      420

agtgccctcc tccatcggct gtctgatgac tgctgggaaa agataacagc atggatttat      480

ggaatgggac tctgtgccct cttcatcgtt tctacagtat ttcacattgt atcatggaaa      540

aagagccact taaggacagt ggagcattgt tttcacatgt gtgatagaat ggttatctat      600

ttcttcattg ctgcttctta tgctccatgg ttaaatcttc gtgaacttgg acccctggca      660

tctcatatgc gttggtttat ctggctcatg gcagctggag gaaccattta tgtatttctc      720

taccatgaaa aatataaggt ggttgaactc tttttctatc tcacaatggg attctctcca      780

gccttggtgg tgacatcaat gaacaacacc gatggacttc aggaacttgc ctgtgggggc      840

ttaatttatt gcttgggagt tgtgttcttc aagagtgatg gcatcattcc atttgcccac      900

gccatctggc acctgtttgt ggccacggca gctgcagtgc attactacgc catttggaaa      960

tacctttacc gaagtcctac ggactttatg cggcatttat gaccaatctg tactaattct     1020

ccaaaccagt attatttcaa ttatggcact tgggagtggg gtgagagcta aacattgcac     1080

agggaaagaa aaaaaataac tgcactgact ttatatcttt tgaatataat tactgtgaaa     1140

gtataaaggc tgtgttctgg aattttctgc ctcacagcaa ataaataagg tagtgaatta     1200

attattcatt ccattccact atcatgaagg actctgaata gacttggcca actgatgttt     1260

acaaaccaga cttttatatt ttaattttac agattttact acatgatttt tctaaattac     1320

tatgtcaggt tgtaaaagtc agtgcaataa caaaccttcc tttttaagaa gaaaattgtt     1380

tctattactt tcccattcac taggtaaaga atcatggaca gaacttacac tactttttac     1440

catgtttcat cttggcataa catggttctt ttttaaatag aaactttagt tttttgtaaa     1500

tttttaaaaa aatatttcat tgatatgcat ctctgcaggt cctcattcat gttgtaaatt     1560

tttgcagcaa gcagtcaaca ttccacaaac gaacaaacat tatacctctt ctgatagttt     1620

tattaagcat ggagaaattg ccaattttta aaaactgcag ttttccaaac ttttctgcca     1680

acctcttact ctgaattcag tgctgctttg ggacatatac ttgacctagc ttggtttacc     1740

agtgatggaa aagtattttg atatcattaa ctttttcaaa agatccaact ttttctctat     1800

gcctttgcca cattctcttc agggtctctt tccacagtgg ataaatgttt tttctgtatt     1860

atgacagtat tgttgtgatg gccatctgct ggaaactcct gaagagcatt atgtattaca     1920

gtgagcagtt gtattgcctg tttggtgccc aatggttaag tcattgtcac ttagctttat     1980

attgtcagtt tgatatttat tttaaattgt ggaactagat gcataaattc acatttctgc     2040

ctttcctttg catcttctca tatattgtgt tttttttttt ttttcctaga aaaaatattt     2100

aaagcattgt ttgacaggta gaaactcatg tatctgtagt ccatgagtta tatcctggct     2160

cagtggagtg atatttatgt attattttta cttttctctc agtgtcttat attaagatta     2220

acatgttgtt aatagttgct ttgttgatta atctctcttg ttggtgtttt aataaatgaa     2280

ataggcttgc ctttagatcg ggtgctgata ttgcctgttt cctagtaatg ggctgatcaa     2340

atgatcagtg gaattcttgg tttgatgata accttattaa ttgaaatttt ttactgatgt     2400

ggctttaaaa gaggtttatt ttgtatatgt ttagaactct ctgattttga tgaattatat     2460

gggaatgaga aacagaagaa gtggtatttg ctggcgagtt aaataggcaa ggtacccagt     2520

gataacacca accaaaccac tcctatctgc atgattctga acatctggat gcctgttgtt     2580

ttactgtgta tattttattt ttaatatatt aactttgtgg attcatttaa ggtctactca     2640

aaagtaacac tgtcaaaacc actaatatgt atgtaaaaat tgtgctgtat actacaataa     2700

agttgttact tggatttgtt cca                                             2723


<210>  100
<211>  3392
<212>  DNA
<213>  homo sapiens

<400>  100
tttctctctc tctctctctt aaagttggcg cgctctcttc acaagttcca tcactaccca       60

agaagtgagg gggcgggggg gacaggcggg aaggcattaa ttacacctaa atctgaagtt      120

tgcggcctca agtaccactt tgatggggag agcttctgaa gcttccatac aacctgccgt      180

gcctttgctg ctgccgcagt agattttcag ctcatttctt tctgctgctg cttcgcgctg      240

ctctgtcatg cctaaatcta tctcgtcact gccaaaggtg cctgaatcag ggtgaattcc      300

acgagattca ccagcggttt tgctccagtc caaggaggag gcgcgcagcc cagctcccct      360

agtctctctt cttaaatccc cctacctacg gctgccgagg ttggccgcgc gtcgggaatc      420

tccccgacag tcctggccct cccccgcccc ccgggttggt ttttcccagc tgcggaggtt      480

gggaggttgg gccaggggct ggggtgcgaa gagagtcggc gcccgcaacg cggagccggg      540

aagtcgtcgc tactctggtg gaactcagag ttggttctgg aggcggcgga cgcggaggtc      600

cctcagagga tccagcgagg ggcgccaaca agaggcgaag aggtggcacc agggcggcgg      660

caggaagagg agcgggagca ggagcgcgga gcggagcgtc ccgacccgcc gtgcgtactt      720

tctggaggga aggggcgggg gaatcggccc ctgagggaag cgcccggtgg cgagggggtt      780

agccaagttc cggctgcggc gccactccct cggttccacg agaggaaagt tttttttttc      840

cagacgcttc cgccggctcg cgccctccgg gcccagcctc ccgagccttc ggagcgggcg      900

ccgtcccagc ccagctccgg ggaaacgcga gccgcgatgc ctggggggtg ctcccggggc      960

cccgccgccg gggacgggcg tctgcggctg gcgcgactag cgctggtact cctgggctgg     1020

gtctcctcgt cttctcccac ctcctcggca tcctccttct cctcctcggc gccgttcctg     1080

gcttccgccg tgtccgccca gcccccgctg ccggaccagt gccccgcgct gtgcgagtgc     1140

tccgaggcag cgcgcacagt caagtgcgtt aaccgcaatc tgaccgaggt gcccacggac     1200

ctgcccgcct acgtgcgcaa cctcttcctt accggcaacc agctggccgt gctccctgcc     1260

ggcgccttcg cccgccggcc gccgctggcg gagctggccg cgctcaacct cagcggcagc     1320

cgcctggacg aggtgcgcgc gggcgccttc gagcatctgc ccagcctgcg ccagctcgac     1380

ctcagccaca acccactggc cgacctcagt cccttcgctt tctcgggcag caatgccagc     1440

gtctcggccc ccagtcccct tgtggaactg atcctgaacc acatcgtgcc ccctgaagat     1500

gagcggcaga accggagctt cgagggcatg gtggtggcgg ccctgctggc gggccgtgca     1560

ctgcaggggc tccgccgctt ggagctggcc agcaaccact tcctttacct gccgcgggat     1620

gtgctggccc aactgcccag cctcaggcac ctggacttaa gtaataattc gctggtgagc     1680

ctgacctacg tgtccttccg caacctgaca catctagaaa gcctccacct ggaggacaat     1740

gccctcaagg tccttcacaa tggcaccctg gctgagttgc aaggtctacc ccacattagg     1800

gttttcctgg acaacaatcc ctgggtctgc gactgccaca tggcagacat ggtgacctgg     1860

ctcaaggaaa cagaggtagt gcagggcaaa gaccggctca cctgtgcata tccggaaaaa     1920

atgaggaatc gggtcctctt ggaactcaac agtgctgacc tggactgtga cccgattctt     1980

cccccatccc tgcaaacctc ttatgtcttc ctgggtattg ttttagccct gataggcgct     2040

attttcctcc tggttttgta tttgaaccgc aaggggataa aaaagtggat gcataacatc     2100

agagatgcct gcagggatca catggaaggg tatcattaca gatatgaaat caatgcggac     2160

cccagattaa cgaacctcag ttctaactcg gatgtctgag aaatattaga ggacagacca     2220

aggacaactc tgcatgagat gtagacttaa gctttatccc tactaggctt gctccacttt     2280

catcctccac tatagataca acggactttg actaaaagca gtgaagggga tttgcttcct     2340

tgttatgtaa agtttctcgg tgtgttctgt taatgtaaga cgatgaacag ttgtgtatag     2400

tgttttaccc tcttcttttt cttggaactc ctcaacacgt atggagggat ttttcaggtt     2460

tcagcatgaa catgggcttc ttgctgtctg tctctctctc agtacagttc aaggtgtagc     2520

aagtgtaccc acacagatag cattcaacaa aagctgcctc aactttttcg agaaaaatac     2580

tttattcata aatatcagtt ttattctcat gtacctaagt tgtggagaaa ataattgcat     2640

cctataaact gcctgcagac gttagcaggc tcttcaaaat aactccatgg tgcacaggag     2700

cacctgcatc caagagcatg cttacatttt actgttctgc atattacaaa aaataacttg     2760

caacttcata acttctttga caaagtaaat tacttttttg attgcagttt atatgaaaat     2820

gtactgattt ttttttaata aactgcatcg agatccaacc gactgaattg ttaaaaaaaa     2880

aaaaaataaa gattcttaaa agaattacag tgtgtgcaag tttgctttga aaaaaggatg     2940

aagggcagga gtattcaatg gtcttggttc cgatgataat tattacttaa catagctgag     3000

aatcaaactg tagcaatgtc taatataaat agacttggga gatcgttttg aaatggtgga     3060

tccttttagt atttaaatgg agagtttgag tattcatgtg actgtatggt cccaaagtta     3120

atgctattta tgaaacagtt ttgtaagaac ataatgaagt tggtaaaagc taagcgttct     3180

gcacaataaa cagttcccag tttggggctt tttcaaggct aatgaagtta ttgttggtct     3240

agaaaaatag tatttactta ataaaactct gtttgaaatt gttctgtgga tttttagagc     3300

agaatttgaa acaaatgtaa tgcaaataaa tataaagata aagtgtctta aagacaatat     3360

tctgaaataa aagatataaa atataattta aa                                   3392


<210>  101
<211>  2096
<212>  DNA
<213>  homo sapiens

<400>  101
gcctttgcgc acgcgcacga acgcacggcc gcgcagcatc tgtcttgctg gaagcttttt       60

cctagaggtt gagcggtttg cacaatgtcg gaaatggctg agttgtccga gctgtatgaa      120

gagagcagtg acctgcagat ggatgtgatg cctggcgagg gtgaccttcc gcagatggag      180

gtaggcagcg ggagccggga gctatccctg cgtccctccc gcagcggggc ccaacagctc      240

gaggaggaag gcccaatgga ggaggaggag gcccagccaa tggcggcgcc agaggggaaa      300

cggagccttg ctaacgggcc caacgctggg gagcagccag gccaggtggc gggcgcagac      360

ttcgagagcg aggacgaggg cgaggaattt gatgactggg aggacgacta cgactatccc      420

gaagaggagc agctcagtgg tgccggctac agagtatcag ccgctcttga agaagccgac      480

aagatgtttc tgagaacaag agaaccagcc ctggatggcg ggtttcagat gcattatgag      540

aagaccccgt ttgatcagtt agcttttatc gaagagcttt tttcactgat ggttgtcaat      600

cgtctgaccg aagaactcgg ctgtgatgag attattgata gagagtagtt agatgctgtt      660

aaaagaggag gaaactactt gaggagggac ccaactttcc gctatctttt gggttcattc      720

caaatagttt tgtgccattg aaaaacttga ccttcaaaaa aatttgtttt tcagaataga      780

acacaatagg acagtgactg cacagttgtg aaaaaggaag agaatcatta aagaaaaaga      840

aaaaagattt taagaccgtt gaaatcaatt atcaagaacg tcctaaaaca cctatggctt      900

tgactttgtt attgatccag attattttcc ttgcattggg gaaaatatct ttcatatttg      960

tttgctgtaa agatggtttt gcaagaataa gtcatgacca agacaaactg ccaatacaaa     1020

agcccactga tactaattat ataatgagaa aaaaatgtat ccaactagga cacatatctt     1080

ttgagttatt tggactgaaa gcttaagaaa acttggaaaa ttctattttg tgatctagtc     1140

aagccacagt tatcaaaggc tacattttca gtgtaagata aatggatgag taaactcaaa     1200

tatgtatcac gtgtgctttg tatcttaaga tgtgtttcca agagcatctg aaattttgtt     1260

tgtacatgta tcttgatcat ttataaagcc actgtgatct ataaatcaag aaaatccatt     1320

gtcataacca tttttaaaag tcaaaaatta agacatcctt aattaaaaag tttcaaatct     1380

agacactaaa tgtgtgtgaa tgtacaaaga aaacaaacca ttgcttatgc tgttatatac     1440

tagagaaatt ttgttttgct tgctgtttta acttgacaga tgaaggactt tagttgaact     1500

tcatattgta agaactgtta ataaaagttg tcaagtaaaa agcgctatat ctaaaaagac     1560

tttatgaaca gttattctat caacttttaa aggttttaaa cctgcccaga aattaccttg     1620

gtatctgaag tttccctctg tctcctcctc taattaagct tgttatttgt catgcaccag     1680

cattggagat aataaaattt cttgttctgt gtattttgtt tggctaatag tattgcatac     1740

atactttctc tgtatactac tttctattgt atgtgttaac cagtattaag ggaaaatgat     1800

ccagcttcag ctatctaatt cacaaattaa tttctggaaa ttaaactttg taaattaagt     1860

ttttgcctat aagaatttgc tggtctggga aaacctgccc tatcaatgag tatgttgccg     1920

tggttacctt actaagatgc tgaagttcta ggagagtaat gattacatca gaaggctagg     1980

ttcagcaaaa taagtgtatc agcaggtttt atcatgatca gtaaaaatgt tccaaatgct     2040

tctgctccat tatagcagta aagaacgaat atccaatgca acaggacaat taaaaa         2096


<210>  102
<211>  2096
<212>  DNA
<213>  homo sapiens

<400>  102
gcctttgcgc acgcgcacga acgcacggcc gcgcagcatc tgtcttgctg gaagcttttt       60

cctagaggtt gagcggtttg cacaatgtcg gaaatggctg agttgtccga gctgtatgaa      120

gagagcagtg acctgcagat ggatgtgatg cctggcgagg gtgaccttcc gcagatggag      180

gtaggcagcg ggagccggga gctatccctg cgtccctccc gcagcggggc ccaacagctc      240

gaggaggaag gcccaatgga ggaggaggag gcccagccaa tggcggcgcc agaggggaaa      300

cggagccttg ctaacgggcc caacgctggg gagcagccag gccaggtggc gggcgcagac      360

ttcgagagcg aggacgaggg cgaggaattt gatgactggg aggacgacta cgactatccc      420

gaagaggagc agctcagtgg tgccggctac agagtatcag ccgctcttga agaagccgac      480

aagatgtttc tgagaacaag agaaccagcc ctggatggcg ggtttcagat gcattatgag      540

aagaccccgt ttgatcagtt agcttttatc gaagagcttt tttcactgat ggttgtcaat      600

cgtctgaccg aagaactcgg ctgtgatgag attattgata gagagtagtt agatgctgtt      660

aaaagaggag gaaactactt gaggagggac ccaactttcc gctatctttt gggttcattc      720

caaatagttt tgtgccattg aaaaacttga ccttcaaaaa aatttgtttt tcagaataga      780

acacaatagg acagtgactg cacagttgtg aaaaaggaag agaatcatta aagaaaaaga      840

aaaaagattt taagaccgtt gaaatcaatt atcaagaacg tcctaaaaca cctatggctt      900

tgactttgtt attgatccag attattttcc ttgcattggg gaaaatatct ttcatatttg      960

tttgctgtaa agatggtttt gcaagaataa gtcatgacca agacaaactg ccaatacaaa     1020

agcccactga tactaattat ataatgagaa aaaaatgtat ccaactagga cacatatctt     1080

ttgagttatt tggactgaaa gcttaagaaa acttggaaaa ttctattttg tgatctagtc     1140

aagccacagt tatcaaaggc tacattttca gtgtaagata aatggatgag taaactcaaa     1200

tatgtatcac gtgtgctttg tatcttaaga tgtgtttcca agagcatctg aaattttgtt     1260

tgtacatgta tcttgatcat ttataaagcc actgtgatct ataaatcaag aaaatccatt     1320

gtcataacca tttttaaaag tcaaaaatta agacatcctt aattaaaaag tttcaaatct     1380

agacactaaa tgtgtgtgaa tgtacaaaga aaacaaacca ttgcttatgc tgttatatac     1440

tagagaaatt ttgttttgct tgctgtttta acttgacaga tgaaggactt tagttgaact     1500

tcatattgta agaactgtta ataaaagttg tcaagtaaaa agcgctatat ctaaaaagac     1560

tttatgaaca gttattctat caacttttaa aggttttaaa cctgcccaga aattaccttg     1620

gtatctgaag tttccctctg tctcctcctc taattaagct tgttatttgt catgcaccag     1680

cattggagat aataaaattt cttgttctgt gtattttgtt tggctaatag tattgcatac     1740

atactttctc tgtatactac tttctattgt atgtgttaac cagtattaag ggaaaatgat     1800

ccagcttcag ctatctaatt cacaaattaa tttctggaaa ttaaactttg taaattaagt     1860

ttttgcctat aagaatttgc tggtctggga aaacctgccc tatcaatgag tatgttgccg     1920

tggttacctt actaagatgc tgaagttcta ggagagtaat gattacatca gaaggctagg     1980

ttcagcaaaa taagtgtatc agcaggtttt atcatgatca gtaaaaatgt tccaaatgct     2040

tctgctccat tatagcagta aagaacgaat atccaatgca acaggacaat taaaaa         2096


<210>  103
<211>  4431
<212>  DNA
<213>  homo sapiens

<400>  103
gagtcgcggc gccatttgct gccgccgagc gtggacgcag gcggatctct gaagagctgg       60

gtcgccagcc tctcccgcgc acgttgcctg gcctccagca cctacttggt cccgcgcgct      120

ccctcgtgtc gcccctcgga gcagcagccg ccgcggtcgc cgctacccgg aaagaagtca      180

gagacgccgc gaggtcgccg ccaccgccat gcccaagaat aaaggtaaag gaggtaaaaa      240

cagacgcagg ggtaagaatg agaatgaatc tgaaaaaaga gaactggtat tcaaagagga      300

tggtcaggag tatgctcagg taatcaaaat gttgggaaat ggacggctag aagcaatgtg      360

tttcgatggt gtaaagaggt tatgtcacat cagaggaaaa ttgagaaaaa aggtttggat      420

aaatacctcg gacattattt tggttggtct ccgagactac caggataaca aagctgatgt      480

aattttaaaa tacaatgcag acgaagctag aagtctgaag gcatacggcg agcttccaga      540

gcatgctaaa atcaatgaaa ctgatacatt tggtcctgga gatgatgatg aaattcagtt      600

tgatgacatt ggagatgatg atgaagatat tgatgacatc taaattgaac tcaacatttt      660

acattccatc ttttctgaag attgtcctac aatttggatt ttgatcatga caaagaagat      720

taaaatttca ttagcatgaa tgcaatttgt taaagcagac tgatttgttt ctaagatatt      780

tttggttttt ttaaaactga taataatgct gaattatctt aagtgagatg ttaagcccac      840

tttgttcttt taatgtaatg gagcttatgg gtagaagacc atgtctacta attacaaaaa      900

aaaaaaaaaa ccatgcattg ctgcttttcc taccacttcc agtaagaaaa tgggtgtttt      960

gaagaaatca tttgccttgt cctcacggaa tctgattaag ccctggcctc ttgattgtat     1020

agagtcattg tgtatattcc agttacctag atattccctt gagattttga tacaatttga     1080

gggaggcaga agtctgcagt tgaagaaaaa aaataagtct gtttgtcata tttaagtagc     1140

ctgtggctat ttttatactg attttgatat catgttcttt tcatagtcgt attttgccac     1200

cgtaaacata aaaaaaaaaa aaaagatttc caaaatgccg ttttcagaac ctgggtttta     1260

atagcagtat tgaatttgta agcttagtag ttgcagaaat tgaacactag gtggcactca     1320

gttatcttaa caggggaagt actgatacaa ttgttgactt ttcttttact atgtgtaaga     1380

aataccccaa acatgaaaag attgttttga tcatatgcat gtatgtagaa tatttttgca     1440

gagcagaaag attatgttag aagtgtgatt tttattttca gaagtcatat acatgtaagc     1500

tacaattttg agtgctttat aaacacttaa gatatatata taaattttaa tttcatagca     1560

acttgtaaaa aataaaatac ttgttgaaaa gcctttttca acatatccct aagctaaggg     1620

aagaggaagg aataacaact cagtgaaaag atggtctcca gtttctgaat gaaaaagcta     1680

cagctgagaa ataaaataaa atgtcatgct gcagaatatg ttataccctt attttgtgtt     1740

aaggatatat tttattatgt gaatggtttt gtttttgttt tttgtttttg ttttttgctt     1800

gtattgggaa ttagctttac tggtaacttc cttatttagt ttttagtggt caactctaat     1860

aaaatgaaac tagggctgag ctagttagcc ctcactagcc aaactgaaac tctatgcaac     1920

attaaaagaa gagatccatc atgtagcttg tgacactttt attttattag tcaccgggga     1980

acttttcagt gatgaaaata cacagggtaa taaaccttca catggcttca aaaggaaaac     2040

aagcaaatct tctctaatct actcttacta taatttccta agtgtacacc aaactctgga     2100

tttaaaaatc tgaagtacta tagaacatta agttgaagaa tggaaattaa gagtacgtat     2160

tcatggttta tatttcttat tctatggagt tcgtgaacac atctaggtgg aatgcatctg     2220

agactaaggg ctggttttta atcctcataa gaaaccagcc ttgaagaatt aacaattctc     2280

ttcattggta ttctaaacct cctaagatat ttaggcttct gtacataaaa gtgtttttgc     2340

taaatttaca gtatatatag atcctttcat attattttac taagaatgtt tgaactttgc     2400

atatttgata tagttcctgg taggaatagc acagctcaaa cattagtttt tctacttacc     2460

tcctctaaca cgtggtttgt ctggagagtt tctaaaaatt cagctataac cccagttcat     2520

gtatttactg gtgattgttc ttgctgaggt agtaacagcc caatcttggg ctgttaaatc     2580

ctaggaaatc tcgaatcata gtgattaaaa tagttggggt aaagttgtag cttatatgca     2640

atactacttg gaggaattct tctactaatt tgtatttaat gtggaaattg tatagtttca     2700

ttgatttaat cataaataat ggaaatggtc tccaagaagt tttatttttc atttttttgc     2760

ttatacactc tgattcctat aatacagtgc tataagctat gcacagaaaa taaaatgttt     2820

gaaatccaag aataatggtt cttactgcta agagggagta atagttatta ctaatgattt     2880

tgattgggtt gcatttttgt tgcaatgttt attccacttg cagttagaat atgaatatgt     2940

tttatcacta gtgtggctaa ataaccaaac atttgtgtaa aaaaaaaaaa aagccaagat     3000

ttcattgttt gttgaatatt tcttaagcat ctggccccta aagagaccgc ttcttaccaa     3060

gcctgtaaac tatgcatgat ggaaattctt gtattttatt taggaatggc tgttggttta     3120

ctcaccacat ctgtggaatc atggctataa atgtttgctt acaaactctt tgtgacttgt     3180

aatttaactt aatctcatct aatgtaaata ttagattatg atgttcagta acatcttcca     3240

taggtataaa ctgctgtcat tattgatttc agagtaactc tgagtaatca aataggtaaa     3300

agcatgtttt gagtaaaata gctagattta tactttactt gtatacagac ttaacaacaa     3360

ccggtattga ctggattgac agctaaagta tcagaatgaa agcaaggttt ttttgatgtt     3420

acctgactgt cataaagatg aaaatgattt gtattggtat gaaatgctta tctttattct     3480

acttcgtaag ggtaagtttt atttatactc tttggactcc catgaacttt tgcacactgc     3540

tttgtgtttt tggtttaccc taaactacca tcctttttat ctttgctttt tttcttccta     3600

ttcagaaaag agcaaaatgt gaaaagacac aagactctca ggtatagaat gaactgagca     3660

atttggagaa tgtattggac tttgtcctct cttattcccc cctcctagcc ctgcaagttg     3720

ctaggtactt gtgaggcagt gtactggaga ggggagagca tggatcctgg ggtcaaaggg     3780

cctttgcccc cacccttact tggccctcta cctgcaggtg accactggca cattctcctg     3840

cttgtctcag cttcaggttc ttcacctcta agatggggat gatgaaaaca gtacctgtca     3900

tgcagaattg ttgggaggat tgataattta gatgtttata catgtaatgt acttagatca     3960

gtgtctgctc ttttcacttg atatccagta ctatgtaaga tagaaggtgc atgtcttctg     4020

tattctgtat ttcccatttc ttttgcgtgc agtctttgat tcgtacaata gaaggaacac     4080

gtagaatgta tatttgtaca ttcatgtcaa catagtattt gaaattgcta ccaaactcat     4140

ttaatttggc ataagactaa cagatgaagt ctctcatttg cttgaagata ttttacaaaa     4200

taccaactgt tctatatttc tttagaaaaa gattatagtt attaatattg atacctctga     4260

taatatttta ttcttaaatc ttcagtgatt ccttttacta tagattcatg acagctaatt     4320

agtactaact gatttagagg tttcctttcc catcatatgg aatgatgtaa agaaatcaga     4380

tacaaactac tgcaattaga aaataaaata tgaacaactt tcaacaatgt a              4431


<210>  104
<211>  2988
<212>  DNA
<213>  homo sapiens

<400>  104
aactacaaaa ttgaaagtag agaggagggg gcagccaatg gaaaaaaaaa tttgcacagc       60

agccaatcct cctgcggcgt tttgtgcctt tgcccaacag gaaaatgtgt ctcatgcaga      120

ggggcgttac ccagtctcca atgggcggga gccggtggaa cggaggagcc aatgagtgcg      180

agatgttgag tgacagctgt ccaatggagg ccctccgtgc tagtacggct tgcggcttaa      240

gcgccgccgc ggtctgcgga atgtcaacta ttcaacatgg aggcggaggt cgataagctg      300

gaactgatgg tgagtgcaaa gtgaaggaga tctactgggt agtttatttt tcccccatgg      360

cctcggaggt ggggcacaat ttggagtcgc cggaaactcc gggcggcgga ggctggacca      420

gagtcgagtt ccctcctcct gcaccaaagg gagccgccac cgtctggtgt ctaaaccgcc      480

tcggttccag aaagctgagt ctgatctgga ttacattcaa tacaggctgg aatatgaaat      540

caagactaat catcctgatt cagcaagtga gctgtcacca ctgactaaag aagagaaaac      600

tgcggcagag caattcaaat ttcacatgcc agatttatga agaaatggac ttggaaagga      660

aattctaaca gagaagagct taattccgga gaaatttagg aagatgtctt gttaaccctt      720

gatgtctaga gattgggggc tggtgaaggg ggtttggctt caatgactgg ataatgatat      780

ctttcatgag agagattata agaagaaggg cagataatat atgaataaag ttcagccaaa      840

aggatcaaat gagaataaaa cgatttaaat atatgtacac acgcatgcac acacacactt      900

agtcttgtaa tttcaggcca gaaattctca acactatttt gcatctgttt tctttttcta      960

agtcatgata atatagatgt tctggtctat cataaaagaa tgtttatgta catttcagtc     1020

attcggtatg tggctttgta aattaaagta taggcaaaac atttgtgtta tacatgatat     1080

ataatttcat tttgtaaatg ttgattgcac atgtggtcac attattgttg agactgcttt     1140

tatgtgacct gtagtctccc acagaaccta aagtaataag ctggcttttc tgtgatagcc     1200

acgtttgcgt atttctttcc ctatttccct tgcctgctaa tgttgaacag catgaacttg     1260

ctttctgatg ctgttttaga ctgtccctgt tgtatctcaa taatatcttt gttttccttc     1320

agcctttatt actataattg ttcattctac atgaaagcta ggaaactgaa attagaagag     1380

cacttatctg ctacttgcca gttttgcgtg agtgtgttat atgtatgtgt caatttccct     1440

ttaaaataac tatttatttt aaaataacta ttggcaataa ggaaactgtt caaagtagag     1500

gcagatcttg atagaaagat gttaatcaca gggttgttta taatagcaat atacatacac     1560

atttggctag tactaggtga ataggaaaat aaatcatgct gtatgtatac aataagaggt     1620

caagttgcca ataaattatt actgttaatg ttctgggaaa tgctgaaact atgctaagtg     1680

ggggagaggg aaagcaggta ttgcagtttt gtagtgaaga ttgggctttg gagtcatatc     1740

tgagatgtaa gtagcagctt ttaaattcta gctatgaccc tgtgcagatc acttaacttt     1800

tgagtgtcag gatgtttgga aggacaagac aggaaagtgt tttaatacag ggttcagtat     1860

ttagtaagcc ttcaataagt gatattacat acatgtaata aaaactaagc attgaaagga     1920

ctaggaaaaa tgcatcaaat gttagttctg caggttatag aattatactt ttatgtaatt     1980

ttaaaatttc agttatgaac atgtttgtcc attaacaaac ttataatagc tgaaaaacag     2040

ggttgtgaga acagcttcag ttaaaattgt cctgtctagt ttgaatattt caagaacaga     2100

aagccttttt tttttttttt ttttttttga gacggagtct cactctgttg cccaggctgg     2160

aatgcagtgg tacgctctca gctcactgca acctccacct cccaggttca agcagttctc     2220

tgccccaccc tcccgagtag ctgggattac aggcgcccgc caccacgccc ggctattttt     2280

ttgtattttt agtagagatg gggcttcacc atcttgacca ggctggtctt taactcctga     2340

tggtgatcca cccacctcgg cctcccaaag tgctgggatt acaggcatga gctaccgtgc     2400

ctggccccct tttttttaat tacagagaaa taagttacac cttagtatca gatattaatt     2460

ttcttcagtg ttcaggcaat tagtatttag aaagctcttg tcatgagatg gctctgggat     2520

gtgatgatga ttgttgggat tgaaaaaacg gtagtatcat ggagagatca taataaattc     2580

ttagtattaa aagtggtttt gctttcagtt agggagaaaa attagattgt actatttttc     2640

ctctatgatt tccttcagtt atcttccaaa tgttgttttt tccccacagc ccccttaaca     2700

ttgttctcta tgcacttctc aatacatttt catttgtttc tcaagcctct ttgtggatga     2760

ctcctaaata taacttcttc cactagctct agatccgtat ttccaataaa atcccctacc     2820

tgaatattca agttaaacat gtccagaata cttactgatt ttattgttaa tagccactat     2880

tctgttgtct ggaattaaaa cctgtataac taatttgcat ccctttatct tcttagtcaa     2940

taaaacctac aatcctcttt ctaaaatggt aaaaaaaaaa aaaaaaaa                  2988


<210>  105
<211>  2656
<212>  DNA
<213>  homo sapiens

<400>  105
gaggctttaa aatctttttt catcttctag ctgtagctcg ggctgcttgt cggcttggcc       60

tccccctccc ccctttgctc tctgcctcgt ctttccccag gacttcgcta ttttgctttt      120

ttaaaaaaag gcaagaaaga actaaactcc cccctccctc tcctccagtc gggctgcacc      180

tctgccttgc actttgcaca gaggtagaga gcgcgcgagg gagagagagg aaagaaaaaa      240

aataataaag agagccaagc agaagaggag gcgagaagca tgaagtgtta actcccccgt      300

gccaaggccc gcgccgcccg gacagacgcc cgccgcgcct ccagccccga gcggacgccg      360

cgcgcgccct gcctgcagcc cgggccggcg aggcgagccc ttccttatgc aaagcgcgca      420

gcggagcggc gagcggggga cgccgcgcac cgggccgggc tcctccagct tcgccgccgc      480

agccaccacc gccgccaccg cagctcgcgg aggatcttcc cgagcctgaa gccgccggct      540

cggcgcgcaa ggaggcgagc gagcaaggag gggccggggc gagcgaggga gcacattggc      600

gtgagcaggg gggagggagg gcgggcgcgg ggggcgcggg cagggcgggg gggtgtgtgt      660

gtgagcgcgc tcggaggttt cgggccagcc accgccgcgc aagctagaag cgccccagcc      720

cggcaagctg gctcacccgc tggccaccca gcacagcccg ctggcccctc tcctgcagcc      780

catctggcgg agcggcggcg gcggcggcgg cggcggcagg agaatggcat cagaactggc      840

aatgagcaac tccgacctgc ccaccagtcc cctggccatg gaatatgtta atgacttcga      900

tctgatgaag tttgaagtga aaaaggaacc ggtggagacc gaccgcatca tcagccagtg      960

cggccgtctc atcgccgggg gctcgctgtc ctccaccccc atgagcacgc cgtgcagctc     1020

ggtgccccct tcccccagct tctcggcgcc cagcccgggc tcgggcagcg agcagaaggc     1080

gcacctggaa gactactact ggatgaccgg ctacccgcag cagctgaacc ccgaggcgct     1140

gggcttcagc cccgaggacg cggtcgaggc gctcatcagc aacagccacc agctccaggg     1200

cggcttcgat ggctacgcgc gcggggcgca gcagctggcc gcggcggccg gggccggtgc     1260

cggcgcctcc ttgggcggca gcggcgagga gatgggcccc gccgccgccg tggtgtccgc     1320

cgtgatcgcc gcggccgccg cgcagagcgg cgcgggcccg cactaccacc accaccacca     1380

ccacgccgcc ggccaccacc accacccgac ggccggcgcg cccggcgccg cgggcagcgc     1440

ggccgcctcg gccggtggcg ctgggggcgc gggcggcggt ggcccggcca gcgctggggg     1500

cggcggcggc ggcggcggcg gcggaggcgg cgggggcgcg gcgggggcgg ggggcgccct     1560

gcacccgcac cacgccgccg gcggcctgca cttcgacgac cgcttctccg acgagcagct     1620

ggtgaccatg tctgtgcgcg agctgaaccg gcagctgcgc ggggtcagca aggaggaggt     1680

gatccggctg aagcagaaga ggcggaccct gaaaaaccgc ggctatgccc agtcctgccg     1740

cttcaagagg gtgcagcaga gacacgtcct ggagtcggag aagaaccagc tgctgcagca     1800

agtcgaccac ctcaagcagg agatctccag gctggtgcgc gagagggacg cgtacaagga     1860

gaaatacgag aagttggtga gcagcggctt ccgagaaaac ggctcgagca gcgacaaccc     1920

gtcctctccc gagtttttca taactgagcc cactcgcaag ttggagccat cagtgggata     1980

cgccacattt tggaagcccc agcatcgtgt acttaccagt gtgttcacaa aatgaaattt     2040

gtgtgagagc tgtacattaa aaaaaatcat cattattatt attatttgca gtcatggaga     2100

accacctacc cctgacttct gtttagtctc ctttttaaat aaaaattact gtgttagaga     2160

agaaggctat taaatgtagt agttaactat gcctcttgtc tgggggtttc atagagaccg     2220

gtaggaaagc gcactcctgc ttttcgattt atggtgtgtg caagtaaaca ggtgcattgc     2280

tttcaacctg ccatactagt tttaaaaatt cactgaaatt acaaagatac atatatatgc     2340

atatatataa tggaaagttt cccggaatgc aacaattagc attttaaaat catatatagg     2400

catgcacatt ctaaatagta ctttttcatg cttcattgtt tctctggcag ataattttac     2460

taagaagaaa aatagatatt cgactcccct tccctaaaca aatccacggg cagaggctcc     2520

agcggagccg agccccctgg ttttctcgta ggccctagac ggtgttgcat ttatcagtga     2580

tgtcaaacgt gctcatttgt cagacatagc tgtaaatgaa aacaatgtgt ggcaaaatac     2640

aaagttaaaa aaaaaa                                                     2656


<210>  106
<211>  6887
<212>  DNA
<213>  homo sapiens

<400>  106
gaggctttaa aatctttttt catcttctag ctgtagctcg ggctgcttgt cggcttggcc       60

tccccctccc ccctttgctc tctgcctcgt ctttccccag gacttcgcta ttttgctttt      120

ttaaaaaaag gcaagaaaga actaaactcc cccctccctc tcctccagtc gggctgcacc      180

tctgccttgc actttgcaca gaggtagaga gcgcgcgagg gagagagagg aaagaaaaaa      240

aataataaag agagccaagc agaagaggag gcgagaagca tgaagtgtta actcccccgt      300

gccaaggccc gcgccgcccg gacagacgcc cgccgcgcct ccagccccga gcggacgccg      360

cgcgcgccct gcctgcagcc cgggccggcg aggcgagccc ttccttatgc aaagcgcgca      420

gcggagcggc gagcggggga cgccgcgcac cgggccgggc tcctccagct tcgccgccgc      480

agccaccacc gccgccaccg cagctcgcgg aggatcttcc cgagcctgaa gccgccggct      540

cggcgcgcaa ggaggcgagc gagcaaggag gggccggggc gagcgaggga gcacattggc      600

gtgagcaggg gggagggagg gcgggcgcgg ggggcgcggg cagggcgggg gggtgtgtgt      660

gtgagcgcgc tcggaggttt cgggccagcc accgccgcgc aagctagaag cgccccagcc      720

cggcaagctg gctcacccgc tggccaccca gcacagcccg ctggcccctc tcctgcagcc      780

catctggcgg agcggcggcg gcggcggcgg cggcggcagg agaatggcat cagaactggc      840

aatgagcaac tccgacctgc ccaccagtcc cctggccatg gaatatgtta atgacttcga      900

tctgatgaag tttgaagtga aaaaggaacc ggtggagacc gaccgcatca tcagccagtg      960

cggccgtctc atcgccgggg gctcgctgtc ctccaccccc atgagcacgc cgtgcagctc     1020

ggtgccccct tcccccagct tctcggcgcc cagcccgggc tcgggcagcg agcagaaggc     1080

gcacctggaa gactactact ggatgaccgg ctacccgcag cagctgaacc ccgaggcgct     1140

gggcttcagc cccgaggacg cggtcgaggc gctcatcagc aacagccacc agctccaggg     1200

cggcttcgat ggctacgcgc gcggggcgca gcagctggcc gcggcggccg gggccggtgc     1260

cggcgcctcc ttgggcggca gcggcgagga gatgggcccc gccgccgccg tggtgtccgc     1320

cgtgatcgcc gcggccgccg cgcagagcgg cgcgggcccg cactaccacc accaccacca     1380

ccacgccgcc ggccaccacc accacccgac ggccggcgcg cccggcgccg cgggcagcgc     1440

ggccgcctcg gccggtggcg ctgggggcgc gggcggcggt ggcccggcca gcgctggggg     1500

cggcggcggc ggcggcggcg gcggaggcgg cgggggcgcg gcgggggcgg ggggcgccct     1560

gcacccgcac cacgccgccg gcggcctgca cttcgacgac cgcttctccg acgagcagct     1620

ggtgaccatg tctgtgcgcg agctgaaccg gcagctgcgc ggggtcagca aggaggaggt     1680

gatccggctg aagcagaaga ggcggaccct gaaaaaccgc ggctatgccc agtcctgccg     1740

cttcaagagg gtgcagcaga gacacgtcct ggagtcggag aagaaccagc tgctgcagca     1800

agtcgaccac ctcaagcagg agatctccag gctggtgcgc gagagggacg cgtacaagga     1860

gaaatacgag aagttggtga gcagcggctt ccgagaaaac ggctcgagca gcgacaaccc     1920

gtcctctccc gagtttttca tgtgagtctg acacgcgatt ccagctagcc accctgataa     1980

gtgctccgcg ggggtccggc tcgggtgtgg gcttgctagt tctagagcca tgctcgccac     2040

cacctcacca cccccacccc caccgagttt ggcccccttg gccccctaca cacacacaaa     2100

cccgcacgca cacaccacac acacacacac acacacacac acaccccaca ccctgctcga     2160

gtttgtggtg gtggtggctg ttttaaactg gggagggaat gggtgtctgg ctcatggatt     2220

gccaatctga aattctccat aacttgctag cttgtttttt tttttttttt acaccccccc     2280

gccccacccc cggacttgca caatgttcaa tgatctcagc agagttcttc atgtgaaacg     2340

ttgatcacct ttgaagcctg catcattcac atattttttc ttcttcttcc ccttcagttc     2400

atgaactggt gttcattttc tgtgtgtgtg tgtgttttat tttgtttgga tttttttttt     2460

taattttact tttagagctt gctgtgttgc ccaccttttt tccaacctcc accctcactc     2520

cttctcaacc catctcttcc gagatgaaag aaaaaaaaaa gcaaagtttt tttttcttct     2580

cctgagttct tcatgtgaga ttgagcttgc aaaggaaaaa aaaatgtgaa atgttataga     2640

cttgcagcgt gccgagttcc atcgggtttt ttttttagca ttgttatgct aaaatagaga     2700

aaaaaatcct catgaacctt ccacaatcaa gcctgcatca accttctggg tgtgacttgt     2760

gagttttggc cttgtgatgc caaatctgag agtttagtct gccattaaaa aaactcattc     2820

tcatctcatg cattattatg cttgctactt tgtcttagca acaatgaact ataactgttt     2880

caaagacttt atggaaaaga gacattatat taataaaaaa aaaaagcctg catgctggac     2940

atgtatggta taattatttt ttcctttttt tttccttttg gcttggaaat ggacgttcga     3000

agacttatag catggcattc atacttttgt tttattgcct catgactttt ttgagtttag     3060

aacaaaacag tgcaaccgta gagccttctt cccatgaaat tttgcatctg ctccaaaact     3120

gctttgagtt actcagaact tcaacctccc aatgcactga aggcattcct tgtcaaagat     3180

accagaatgg gttacacatt taacctggca aacattgaag aactcttaat gttttctttt     3240

taataagaat gacgccccac tttggggact aaaattgtgc tattgccgag aagcagtcta     3300

aaatttattt tttaaaaaga gaaactgccc cattattttt ggtttgtttt atttttattt     3360

tatatttttt ggcttttggt cattgtcaaa tgtggaatgc tctgggtttc tagtatataa     3420

tttaattcta gtttttataa tctgttagcc cagttaaaat gtatgctaca gataaaggaa     3480

tgttatagat aaatttgaaa gagttaggtc tgtttagctg tagatttttt aaacgattga     3540

tgcactaaat tgtttactat tgtgatgtta aggggggtag agtttgcaag gggactgttt     3600

aaaaaaagta gcttatacag catgtgcttg caacttaaat ataagttggg tatgtgtagt     3660

ctttgctata ccactgactg tattgaaaac caaagtatta agaggggaaa cgcccctgtt     3720

tatatctgta ggggtatttt acattcaaaa atgtatgttt ttttttcttt tcaaaattaa     3780

agtatttggg actgaattgc actaagatat aacctgcaag catataatac aaaaaaaaat     3840

tgcaaaactg tttagaacgc taataaaatt tatgcagtta taaaaatggc attactgcac     3900

agttttaaga tgatgcagat ttttttacag ttgtattgtg gtgcagaact ggattttctg     3960

taacttaaaa aaaaatccac agttttaaag gcaataatca gtaaatgtta ttttcaggga     4020

ctgacatcct gtctttaaaa agaaatgaaa agtaaatctt accacaataa atataaaaaa     4080

atcttgtcag ttacttttct tttacatatt ttgctgtgca aaattgtttt atatcttgag     4140

ttactaacta accacgcgtg ttgttcctat gtgcttttct ttcattttca attctggtta     4200

tatcaagaaa agaataatct acaataataa acggcatttt tttttgattc tgtactcagt     4260

ttcttagtgt acagtttaac tgggcccaac aacctcgtta aaagtgtaaa atgcatcctt     4320

ttctccagtg gaaggattcc tggaggaata gggagacagt aattcagggt gaaattatag     4380

gctgtttttt gaagtgagga ggctggcccc atatactgat tagcaatatt taatatagat     4440

gtaaattatg acctcatttt tttctcccca aagttttcag ttttcaaatg agttgagcca     4500

taattgccct tggtaggaaa aacaaaacaa aacagtggaa ctaggcttcc tgagcatggc     4560

cctacacttc tgatcaggag caaagccatc catagacaga ggagccggac aaatatggcg     4620

catcagaggt ggcttgcgca catatgcatt gaacggtaaa gagaaacagc gcttgccttt     4680

tcactaaagt tgactatttt tccttcttct cttacacacc gagattttct tgttagcaag     4740

gcctgacaag atttaacata aacatgacaa atcatagttg tttgttttgt tttgcttttc     4800

tctttaacac tgaagatcat ttgtcttaaa taggaaaaag aaaatccact ccttacttcc     4860

atatttccaa gtacatatct ggtttaaact atgttatcaa atcatatttc accgtgaata     4920

ttcagtggag aacttctcta cctggatgag ctagtaatga tttcagatca tgctatcccc     4980

agaaataaaa gcaaaaaata atacctgtgt ggaatatagg ctgtgctttg atttactggt     5040

atttacccca aaataggctg tgtatggggg ctgacttaaa gatcccttgg aaagactcaa     5100

aactaccttc actagtagga ctcctaagcg ctgacctatt tttaaatgac acaaattcat     5160

gaaactaatg ttacaaattc atgcagtttg cactcttagt catcttcccc tagcacacca     5220

atagaatgtt agacaaagcc agcactgttt tgaaaataca gccaaacacg atgacttttg     5280

ttttgttttc tgccgttctt aaaagaaaaa aagataatat tgcaactctg actgaaagac     5340

ttatttttaa gaaaacaggt tgtgtttggt gctgctaagt tctggccagt ttatcatctg     5400

gccttcctgc ctatttttta caaaacacga agacagtgtg taacctcgac attttgacct     5460

tcctttatgt gctagtttag acaggctcct gaatccacac ttaattttgc ttaacaaaag     5520

tcttaatagt aaacctcccc tcatgagctt gaagtcaagt gttcttgact tcagatattt     5580

ctttcctttt tttttttttt tcctcatcac aactaagaga tacacaaact ctgaagaagc     5640

agaaatggag agaatgcttt taacaaaaaa gcatctgatg aaagatttta ggcaaacatt     5700

ctcaaaataa gagtgatatt ctggatgtag ttattgcagt tatctcatga caaatgaggc     5760

ctggattgga aggaaaatat agttgtgtag aattaagcat tttgatagga atctacaagg     5820

tagttgaata taataagcag gtttgggccc ccaaacttta gaaaatcaaa tgcaaaggtg     5880

ctggcaaaaa tgaggtttga gtggctggct gtaagagaag gttaactcct agtaaaaggc     5940

atttttagaa ataacaatta ctgaaaactt tgaagtatag tgggagtagc aaacaaatac     6000

atgttttttt tttcttacaa agaactccta aatcctgagt aagtgccatt cattacaata     6060

agtctctaaa tttaaaaaaa aaaaaatcat atgaggaaat ctagctttcc cctttacgct     6120

gcgtttgatc tttgtctaaa tagtgttaaa attcctttca ttccaattac agaactgagc     6180

ccactcgcaa gttggagcca tcagtgggat acgccacatt ttggaagccc cagcatcgtg     6240

tacttaccag tgtgttcaca aaatgaaatt tgtgtgagag ctgtacatta aaaaaaatca     6300

tcattattat tattatttgc agtcatggag aaccacctac ccctgacttc tgtttagtct     6360

cctttttaaa taaaaattac tgtgttagag aagaaggcta ttaaatgtag tagttaacta     6420

tgcctcttgt ctgggggttt catagagacc ggtaggaaag cgcactcctg cttttcgatt     6480

tatggtgtgt gcaagtaaac aggtgcattg ctttcaacct gccatactag ttttaaaaat     6540

tcactgaaat tacaaagata catatatatg catatatata atggaaagtt tcccggaatg     6600

caacaattag cattttaaaa tcatatatag gcatgcacat tctaaatagt actttttcat     6660

gcttcattgt ttctctggca gataatttta ctaagaagaa aaatagatat tcgactcccc     6720

ttccctaaac aaatccacgg gcagaggctc cagcggagcc gagccccctg gttttctcgt     6780

aggccctaga cggtgttgca tttatcagtg atgtcaaacg tgctcatttg tcagacatag     6840

ctgtaaatga aaacaatgtg tggcaaaata caaagttaaa aaaaaaa                   6887


<210>  107
<211>  4447
<212>  DNA
<213>  homo sapiens

<400>  107
ggagacgctg ggcgcgctgt ggggcggggg cgaggttcgg gctggttgtt ccgttgcgag       60

ctgcagctgc gatctctgtg gtaggcccag aagtgtatgc tgacttgtaa agtgaagaag      120

ccagtggtgc tgcgggtgtt cttttggggt agtgtctggg atccagtacg agttgaatca      180

ttgttcaaat aaggtgtaat tgaaaagtga tcctctcttc agagatgtca aaaacaaaca      240

aatccaagtc tggatctcgc tcttctcgct caagatctgc atcaagatct cgttctcgtt      300

cattttcgaa gtctcggtcc cgaagccgat ctctctctcg ttcaaggaag cgcaggctga      360

gttctaggtc tcgttccaga tcatattctc cagctcataa cagagaaaga aaccacccaa      420

gagtatatca gaatcgggat ttccgaggtc acaacagagg ctatagaagg ccctattatt      480

tccgtgggcg taacagaggc ttttatccat ggggccaata taaccgagga ggctatggaa      540

actaccgctc aaattggcag aattaccggc aagcatacag tcctcgtcga ggccgttcaa      600

gatcccggtc cccaaagaga aggtcccctt caccaaggtc caggagccat tctagaaact      660

ctgataagtc gtcttctgac cggtcaaggc gctcctcatc ctcccgttct tcctccaacc      720

atagccgagt tgaatcttct aagcgcaagt ctgcaaagga gaaaaagtcc tcttctaagg      780

atagccggcc atctcaggct gccggggata accagggaga tgaggccaag gagcagacat      840

tctctggagg cacctctcaa gatacaaaag catctgagag ctcgaagcca tggccagatg      900

ccacctacgg cactggttct gcatcacggg cctcagcagt ttctgagctg agtcctcggg      960

agcgaagccc agctctcaaa agccccctcc agtctgtggt ggtgaggcgg cggtcacccc     1020

gtcctagccc cgtgccaaaa cctagtcctc cactttccag cacatcccag atgggctcaa     1080

ctctgccgag tggtgccggg tatcagtctg ggacacacca aggtcagttc gaccatggtt     1140

ctgggtccct gagtccatcc aaaaagagcc ctgtgggtaa gagtccacca tccactggct     1200

ccacatatgg ctcatctcag aaggaggaga gtgctgcttc aggaggagca gcctatacaa     1260

agaggtatct agaagagcag aagacagaga atggaaaaga taaggaacag aaacaaacaa     1320

ataccgataa agaaaaaata aaagagaaag ggagcttctc tgacacaggc ttgggtgatg     1380

gaaaaatgaa atctgattct tttgctccca aaactgattc tgagaagcct tttcggggca     1440

gtcagtctcc caaaaggtat aagctccgag atgactttga gaagaagatg gctgacttcc     1500

acaaggagga gatggatgat caagataagg acaaagctaa gggaagaaag gaatctgagt     1560

ttgatgatga acccaaattt atgtctaaag tcataggtgc aaacaaaaac caggaggagg     1620

agaagtcagg caaatgggag ggcctggtat atgcacctcc agggaaggaa aagcagagaa     1680

aaacagagga gctggaggag gagtctttcc cagagagatc caaaaaggaa gatcggggca     1740

agagaagcga aggtgggcac aggggctttg tgcctgagaa gaatttccga gtgactgctt     1800

ataaagcagt ccaggagaaa agctcatcac ctcccccaag aaagacctct gagagccgag     1860

acaagctggg agcgaaagga gattttccca caggaaagtc ttccttttcc attactcgag     1920

aggcacaggt caatgtccgg atggactctt ttgatgagga cctcgcacga cccagtggct     1980

tattggctca ggaacgcaag ctttgccgag atctagtcca tagcaacaaa aaggaacagg     2040

agtttcgttc cattttccag cacatacaat cagctcagtc tcagcgtagc ccctcagaac     2100

tgtttgccca acatatagtg accattgttc accatgttaa agagcatcac tttgggtcct     2160

caggaatgac attacatgaa cgctttacta aatacctaaa gagaggaact gagcaggagg     2220

cagccaaaaa caagaaaagc ccagagatac acaggagaat agacatttcc cccagtacat     2280

tcagaaaaca tggtttggct catgatgaaa tgaaaagtcc ccgggaacct ggctacaagg     2340

ctgagggaaa atacaaagat gatcctgttg atctccgcct tgatattgaa cgtcgtaaaa     2400

aacataagga gagagatctt aaacgaggta aatcgagaga atcagtggat tcccgagact     2460

ccagtcactc aagggaaagg tcagctgaaa aaacagagaa aactcataaa ggatcaaaga     2520

aacagaagaa gcatcggaga gcaagagaca ggtccagatc ctcctcctct tcctcccagt     2580

catctcactc ctacaaagca gaagagtaca ctgaagagac agaggaaaga gaggagagca     2640

ccacgggctt tgacaaatca agactgggga ccaaagactt tgtgggtcca agtgaaagag     2700

gaggtggcag agctcgagga acctttcagt ttcgagccag aggaagaggc tggggcagag     2760

gcaactactc tgggaacaat aacaacaaca gcaacaacga ttttcaaaaa agaaaccggg     2820

aagaggagtg ggacccagag tacacaccca aaagcaagaa gtattacttg catgatgacc     2880

gtgaaggcga aggcagtgac aagtgggtga gccggggccg gggccgagga gcctttcctc     2940

ggggtcgggg ccggttcatg ttccggaaat caagtaccag ccccaagtgg gcccatgaca     3000

agttcagtgg ggaggaaggg gagattgaag acgacgagag tgggacagag aaccgagaag     3060

agaaggacaa tatacagccc acaaccgagt aggggccacc cttgacggga ttcctgccca     3120

ggggagagag gcgctgggaa gatggctggt gaggagctta acagaggaac ctcaagaaga     3180

ttctgaaaat cctaccccca ccccccacca gccgcacaga ttgtactacc gcgagaggca     3240

tccctggcgc tgtctcccac tggacagagg aggctggcca tggggcccag gggtcaggcc     3300

cagcttttga gcagaataca acgcattggg ctttagctgt ttttctcatt tgttggtgtg     3360

tggggtgggg gcaggggtag ggcgggagag cgatgcttgg atttttgttt cctattagaa     3420

accaacagtt ttgttctaat ttcatttcat ttggagctaa gatgactaat ttgatgattt     3480

tcgatctctt ttcccctgtc ctgattttaa aagccccctc cttttttttt ttttttttct     3540

ttttttaggc atatgtagta atattagaaa catttaattt gggaaacttt gattcttgaa     3600

agagaaaaca aaagcatgtg aataaacttt gaagtgttca cctcagtttg ggaccaaact     3660

gcttggatct ttgtaaaaac cggttttgta tgtcaaggag gagtttaagg cctttccgac     3720

caccttgtgt tccccttttc tgcgcagcca tgtatcacgt ggagttgctc cttaccacac     3780

ctcacgtgcc cctgagccct atttcctgat ttcttctggg ctggacttcc ccgttctcca     3840

ccagcagctc cagtatccca aactttctag tcctgctgat cctcccagca acggggtgga     3900

aactggaggg cagtgtctgg tctgttttct aagaaactta tgaattctat tatctttaca     3960

aatatgagaa aattttttca atatttttta ttaatctttt tataaaatga aaagaaactc     4020

ctatgatcga ttaaggaagg tggttatggc tgggtggttc aggggttttt ttgggtttct     4080

tttttttttt ctttgtcttt ttaaccttaa gctgtttaag ttgaagcatt ctcagatgtt     4140

tggggggaaa catcctctta aaatgggtcc ttgtgcttgc cttctgggga ggcggtcctg     4200

agcaggtgaa tcataaggca tttatgcata tgttatatgc ggactgcacc cacctctccc     4260

ccccagcctt tgcctcttgc gttgttgtgc tgctttcccc ttactttgct acatttctat     4320

agttaagttg gttttacttg aatgattcat gtttaggggg aaaatgaaaa tctcccttaa     4380

aatttgtttc aactcctcct gcaaataaaa taaatgaagt ggcagatgta aaaaaaaaaa     4440

aaaaaaa                                                               4447


<210>  108
<211>  1212
<212>  DNA
<213>  homo sapiens

<400>  108
tgcttccccg ccggccgccg ccctcctccc cgggagagag cgaggcgcgc gggtccctct       60

gcgccacccc cgcccccgcc ccttccgagc aaacttttgg cacccaccgc agcccagcgc      120

gcgttcgtgc tccgcagggc gcgcctctct ccgccaatgc caggcgcgcg ggggagccat      180

taggaggcga ggagagagga gggcgcagct cccgcccagc ccagccctgc ccagccctgc      240

ccggaggcag acgcgccgga accgggacgc gataaatatg cagagcggag gcttcgcgca      300

gcagagcccg cgcgccgccc gctccgggtg ctgaatccag gcgtggggac acgagccagg      360

cgccgccgcc ggagccagcg gagccggggc cagagccgga gcgcgtccgc gtccacgcag      420

ccgccggccg gccagcaccc agggccctgc atgccaggtc gttggaggtg gcagcgagac      480

atgcacccgg cccggaagct cctcagcctc ctcttcctca tcctgatggg cactgaactc      540

actcaagtgc tgcccaccaa ccctgaggag agctggcagg tgtacagctc tgcccaggac      600

agcgagggca ggtgtatctg cacagtggtc gctccacagc agaccatgtg ttcacgggat      660

gcccgcacaa aacagctgag gcagctactg gagaaggtgc agaacatgtc tcaatccata      720

gaggtcttgg acaggcggac ccagagagac ttgcagtacg tggagaagat ggagaaccaa      780

atgaaaggac tggagtccaa gttcaaacag gtggaggaga gtcataagca acacctggcc      840

aggcagttta agggctaact taaaagagtt ttttcaatgc tgcagtgact gaagaagcag      900

tccactccca tgtaaccatg aaagagagcc agagagcttt ttgcaccatg catttttact      960

attattttcc aatacttagc accatttcac taaggaacct tgaatacaac caggatcctc     1020

ctttgcatgc gactgtagct gcatttcatg aatagtttga acccttgtca atgcattttt     1080

tgaaaaagaa agaaaaaaaa aacttcgtgt atgtgactca aagcatgtaa ccttaagatg     1140

ttgcattcta aactgacaat aaagaccttt cccaaataaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aa                                                         1212


<210>  109
<211>  3159
<212>  DNA
<213>  homo sapiens

<400>  109
agggcgaacg ggcgagtggc agcgaggcgg ggcgggctga ggccagcgcg gaagtctcgc       60

gaggccgggc ccgagcagag tgtggcggcg gcggcgagat ctgggctcgg gttgaggagt      120

tggtatttgt gtggaaggag gcggaggcgc aggaggaagg gggaagcgga gcgccggccc      180

ggagggcggg aggaggcgcg gccagggcgg gcggttgcgg cgaggcgagg cgaggcgggg      240

agccgagacg agcagcggcc gagcgagcgc gggcgcgggc gcaccgaggc gagggaggcg      300

gggaagcccc gccgccgccg cggcgcccgc cccttccccc gccgcccgcc ccctctcccc      360

ccgcccgctc gccgccttcc tccctctgcc ttccttcccc acggccggcc gcctcctcgc      420

ccgcccgccc gcagccgagg agccgaggcc gccgcggccg tggcggcgga gccctcagcc      480

atggcctcgg gcgacaccct ctacatcgcc acggacggct cggagatgcc ggccgagatc      540

gtggagctgc acgagatcga ggtggagacc atcccggtgg agaccatcga gaccacagtg      600

gtgggcgagg aggaggagga ggacgacgac gacgaggacg gcggcggtgg cgaccacggc      660

ggcgggggcg gccacgggca cgccggccac caccaccacc accatcacca ccaccaccac      720

ccgcccatga tcgctctgca gccgctggtc accgacgacc cgacccaggt gcaccaccac      780

caggaggtga tcctggtgca gacgcgcgag gaggtggtgg gcggcgacga ctcggacggg      840

ctgcgcgccg aggacggctt cgaggatcag attctcatcc cggtgcccgc gccggccggc      900

ggcgacgacg actacattga acaaacgctg gtcaccgtgg cggcggccgg caagagcggc      960

ggcggcggct cgtcgtcgtc gggaggcggc cgcgtcaaga agggcggcgg caagaagagc     1020

ggcaagaaga gttacctcag cggcggggcc ggcgcggcgg gcggcggcgg cgccgacccg     1080

ggcaacaaga agtgggagca gaagcaggtg cagatcaaga ccctggaggg cgagttctcg     1140

gtcaccatgt ggtcctcaga tgaaaaaaaa gatattgacc atgagacagt ggttgaagaa     1200

cagatcattg gagagaactc acctcctgat tattcagaat atatgacagg aaagaaactt     1260

cctcctggag gaatacctgg cattgacctc tcagatccca aacaactggc agaatttgct     1320

agaatgaagc caagaaaaat taaagaagat gatgctccaa gaacaatagc ttgccctcat     1380

aaaggctgca caaagatgtt cagggataac tcggccatga gaaaacatct gcacacccac     1440

ggtcccagag tccacgtctg tgcagaatgt ggcaaagctt ttgttgagag ttcaaaacta     1500

aaacgacacc aactggttca tactggagag aagccctttc agtgcacgtt cgaaggctgt     1560

gggaaacgct tttcactgga cttcaatttg cgcacacatg tgcgaatcca taccggagac     1620

aggccctatg tgtgcccctt cgatggttgt aataagaagt ttgctcagtc aactaacctg     1680

aaatctcaca tcttaacaca tgctaaggcc aaaaacaacc agtgaaaaga agagagaaga     1740

cccttctcga ccacgggaag catcttccag aagtgtgatt gggaataaat atgcctctcc     1800

tttgtatatt atttctagga agaattttaa aaatgaatcc tacacaccta agggacatgt     1860

tttgataaag tagtaaaaat taaaaaaaaa aaactttact aagatgacat tgctaagatg     1920

ctctatcttg ctctgtaatc tcgtttcaaa aacacagtgt ttttgtaaag tgtggtccca     1980

acaggaggac aattcatgaa cttcgcatca aaagacaatt ctttatacaa cagtgctaaa     2040

aatgggactt cttttcacat tcttataaat atgaagctca cctgttgctt acaatttttt     2100

taattttgta ttttccaagt gtgcatattg tacacttttt tggggatatg cttagtaatg     2160

ctacgtgtga tttttctgga ggttgataac tttgcttgca gtagattttc tttaaaagaa     2220

tgggcagtta catgcatact tcaaaagtat tttcctgtaa aaaaaaaaaa gttatatagg     2280

ttttgtttgc tatcttaatt ttggttgtat tctttgatgt taacacattt tgtataattg     2340

tatcgtatag ctgtattgaa tcatgtagta tcaaatatta gatgtgattt aatagtgtta     2400

atcaatttaa acccatttta gtcacttttt ttttccaaaa aaatactgcc agatgctgat     2460

gttcagtgta atttctttgc ctgttcagtt acagaaagtg gtgctcagtt gtagaatgta     2520

ttgtaccttt taacacctga tgtgtacatc ccatgtaaca gaaagggcaa caataaaata     2580

gcaatcctaa agcaagaata tggcagaaca agatctgtaa gcacagtctt attttctttt     2640

gttgtccaga atacttataa ttcttgagcc tcccagaaat tggaagctaa ataaagcaac     2700

tcaagtttcc tttattttgc actcaattac agtgattatt gatgaaagcg atgcatggat     2760

attttaatac ttcctacatg tcctgacttc tgaaagagag taggtaacag gcatcccgag     2820

ttcaggaact acctcagaac accccaggcc aggttggtca taggctgtga ttttagcccc     2880

cggcaagtgt gagtgaagca tctgtaccac cgcgcaggct gagcgcctgc gcagggtaag     2940

gtgccacctg gcagtggggc acacagaggg aagaccaggc ctgtccatca gccggctgcc     3000

ttcagaggca gctccagcag gaccttggct tgtctgacag gaaatgcttg tggtcgttgg     3060

ttatttggtt tgagagccct tgttcctcca tctagtggag tccttattaa atgctagcaa     3120

tgtggcaatt gagtgccagt agcttaattt catgtttct                            3159


<210>  110
<211>  1310
<212>  DNA
<213>  homo sapiens

<400>  110
catttgggga cgctctcagc tctcggcgca cggcccagct tccttcaaaa tgtctactgt       60

tcacgaaatc ctgtgcaagc tcagcttgga gggtgatcac tctacacccc caagtgcata      120

tgggtctgtc aaagcctaca ctaactttga tgctgagcgg gatgctttga acattgaaac      180

agccatcaag accaaaggtg tggatgaggt caccattgtc aacattgtga ccaaccgcga      240

caatgcacag agacaggata ttgtcttctc ctaccagaga aggaccaaaa aggaacttgc      300

atcagcactg aagtcagcct tatctggcca cctggagacg gtgattttgg gcctattgaa      360

gacacctgct cagtatgacg cttctgagct aaaagcttcc atgaaggggc taggaaccga      420

cgaggactct ctcattgaga tcatctgctc cagaaccaac caggagctgc aggaaattaa      480

cagagtctac aaggaaatgt acaagactga tctggagaag gacattattt cggacacatc      540

tggtgacttc cgcaagctga tggttgccct ggcaaagggt agaagagcag aggatggctc      600

tgtcattgat tatgaactga ttgaccaaga tgcccaggat ctctatgacg ctggagtgaa      660

gaggaaagga actgatgttc ccaagtggat cagcatcatg accgagcgga gcgtgcccca      720

cctccagaaa gtatttgata ggtacaagag ttacagccct tatgacatgt tggaaagcat      780

caggaaagag gttaaaggag acctggaaaa tgctttcctg aacctggtcc agcgcattca      840

gaacaagccc ttgtattttg ctgatcagct gtacgactcc atgaagggca aggggacgcg      900

agataaggtc ctgatcagaa tcatggtctc ccgcagtgaa gtggacatgt tgaaaattag      960

gtctgaattc aagagaaagt acggcaagtc cctgtactat tacatccagc aagacactaa     1020

gggcgactac cagaaagcgc tgctgtacct gtgtggtgga gacgactgaa gcccgacaca     1080

gcctgagcgt ccagaaatgg tgctcaccat gcttccagct aacaggtcta ctaaacatac     1140

aaaagtttag ccgggcgtgg tggcgctcgc ctgtagtccc agctagtccg gaggctgagg     1200

caggagaatg gcttgaaccc ggaaggcaga ggttacagtg agccgagatc atgccactgc     1260

actccagcct gggcaacaga gctagactct gtctctaaat aaataaataa                1310


<210>  111
<211>  1184
<212>  DNA
<213>  homo sapiens

<400>  111
gcaggaccgt cattgacgcc atgagcgcgc tgctgcggct gctgcgcacg ggtgccccag       60

ccgctgcgtg cctgcggttg gggaccagtg cagggaccgg gtcgcgccgt gctatggccc      120

tgtaccacac tgaggagcgc ggccagccct gctcgcagaa ttaccgcctc ttctttaata      180

ttgatgatgt taagaagttc aaaccgggtt acctggaagc tactcttaat tggtttagat      240

tatataaggt accagatgga aaaccagaaa accagtttgc ttttaatgga gaattcaaaa      300

acaaggcttt tgctcttgaa gttattaaat ccactcatca atgttggaaa gcattgctta      360

tgaagaagtg taatggagga gctataaatt gcacaaacgt gcagatatct gatagccctt      420

tccgttgcac tcaagaggaa gcaagatcat tagttgaatc ggtatcatct tcaccaaata      480

aagaaagtaa tgaagaagag caagtgtggc acttccttgg caagtgattg aaacatctga      540

aattctgctg tcaagattcc catctctaag gactccaagt gctagagaca agggggtcta      600

tgagcattta ctgacttcct gttaaaactt cattttttca aactttttga gctatgcaat      660

atataaataa acagtaagaa ttttaaatta ctctcctttg gacatttatt gatataaaaa      720

gaagattttg gccaggcacg gtggctcatg cctgtaattt cagcactttg ggaggccgag      780

gtgggcagat cacaaggtca ggagttcaag accagcctgg ccagtatgtt gaaaccccat      840

ctctattaaa aatacaaaaa ttagccaggc gtggtggtgc atgcctgtag acccagctac      900

tcaggaggct gaggcagaag aactgcttga gcccaggagg cagaggttgc agtgagcaga      960

gattgtgcca ctgcactcca gcctaggcga cagagagaga ctccgtctca aaaaaaaaaa     1020

aaagattttg tttcatttca tagcacaaat ttagaggcat tgagttgacc atttctagtt     1080

tctatacctg aaggaaccca ttgattttac cagtttttat ttctgtagat tggatgtaaa     1140

aatcacagat tcaataaatt aataaacttt gtgtaaaaaa aaaa                      1184


<210>  112
<211>  12262
<212>  DNA
<213>  homo sapiens

<400>  112
agtgtgtggc agcggcggcg gcggcgcggc gaggctgggg ctcttgttta ccagcattaa       60

ctccgctgag cggaaaaaaa aagggaaaaa acccgaggag gagcgagcgc accaggcgaa      120

ctcgagagag gcgggagagc gagagggacg ccgccagcga gcctgcccac ggccggcgct      180

cgcagaccct cggccccgct ccccggatcc ccccgcgccc tccacgcccc tcccgcgcgg      240

gggcagctcc acggcgcgcc tcgcctcggc tgtgaccttc agcgagccgg agcccccgcg      300

cagagcaggc ggcggcgggc gggggccggg cgggggccgg cgcggggcgg gcggcggcgc      360

agagccgggc ggcgcggcgg gagtgctgag cgcggcgcgg ccggcccgcc gctttgtgtg      420

tgtcctggat ttgggaagga gctcgccgcg gcggcggcgg cgctgaggga ggaggcggcg      480

gcgagcggag ccaggaggag gaggaggagg gggagccgct cattcatttt gactccgcgt      540

ttctgcccct cgccggcctc gcctgtgacc cggacttcgg ggcgatcttg cgaactgcgt      600

cgcgccctcc cgcggcggaa gctcgggcgt ccggccgcct cccgcgcggc cagggccggg      660

cttgtttttc ctcgcctagg cagatttggg ctttgccccc tttctttgca gttttccccc      720

cttcctgcct ctccgggttt gaaaatggag gccgacgacg ccgacagccc gccccggcgc      780

gcctcgggtt cccgactccg ccgagccctg ggccgctgct gccggcgctg aggggccgcc      840

ccgcgccgcc cgccccgtcc gcgcacccgg agggccccgg cggcgccgcc ttcggagtat      900

tgtttccttc gcccttgttt ttggaggggg agcgaagact gagtttgaga cttgtttcct      960

ttcatttcct ttttttcttt tcttttcttt tttttttttt tttttttttt tgagaaaggg     1020

gaatttcatc ccaaataaaa ggaatgaagt ctggctccgg aggagggtcc ccgacctcgc     1080

tgtgggggct cctgtttctc tccgccgcgc tctcgctctg gccgacgagt ggagaaatct     1140

gcgggccagg catcgacatc cgcaacgact atcagcagct gaagcgcctg gagaactgca     1200

cggtgatcga gggctacctc cacatcctgc tcatctccaa ggccgaggac taccgcagct     1260

accgcttccc caagctcacg gtcattaccg agtacttgct gctgttccga gtggctggcc     1320

tcgagagcct cggagacctc ttccccaacc tcacggtcat ccgcggctgg aaactcttct     1380

acaactacgc cctggtcatc ttcgagatga ccaatctcaa ggatattggg ctttacaacc     1440

tgaggaacat tactcggggg gccatcagga ttgagaaaaa tgctgacctc tgttacctct     1500

ccactgtgga ctggtccctg atcctggatg cggtgtccaa taactacatt gtggggaata     1560

agcccccaaa ggaatgtggg gacctgtgtc cagggaccat ggaggagaag ccgatgtgtg     1620

agaagaccac catcaacaat gagtacaact accgctgctg gaccacaaac cgctgccaga     1680

aaatgtgccc aagcacgtgt gggaagcggg cgtgcaccga gaacaatgag tgctgccacc     1740

ccgagtgcct gggcagctgc agcgcgcctg acaacgacac ggcctgtgta gcttgccgcc     1800

actactacta tgccggtgtc tgtgtgcctg cctgcccgcc caacacctac aggtttgagg     1860

gctggcgctg tgtggaccgt gacttctgcg ccaacatcct cagcgccgag agcagcgact     1920

ccgaggggtt tgtgatccac gacggcgagt gcatgcagga gtgcccctcg ggcttcatcc     1980

gcaacggcag ccagagcatg tactgcatcc cttgtgaagg tccttgcccg aaggtctgtg     2040

aggaagaaaa gaaaacaaag accattgatt ctgttacttc tgctcagatg ctccaaggat     2100

gcaccatctt caagggcaat ttgctcatta acatccgacg ggggaataac attgcttcag     2160

agctggagaa cttcatgggg ctcatcgagg tggtgacggg ctacgtgaag atccgccatt     2220

ctcatgcctt ggtctccttg tccttcctaa aaaaccttcg cctcatccta ggagaggagc     2280

agctagaagg gaattactcc ttctacgtcc tcgacaacca gaacttgcag caactgtggg     2340

actgggacca ccgcaacctg accatcaaag cagggaaaat gtactttgct ttcaatccca     2400

aattatgtgt ttccgaaatt taccgcatgg aggaagtgac ggggactaaa gggcgccaaa     2460

gcaaagggga cataaacacc aggaacaacg gggagagagc ctcctgtgaa agtgacgtcc     2520

tgcatttcac ctccaccacc acgtcgaaga atcgcatcat cataacctgg caccggtacc     2580

ggccccctga ctacagggat ctcatcagct tcaccgttta ctacaaggaa gcacccttta     2640

agaatgtcac agagtatgat gggcaggatg cctgcggctc caacagctgg aacatggtgg     2700

acgtggacct cccgcccaac aaggacgtgg agcccggcat cttactacat gggctgaagc     2760

cctggactca gtacgccgtt tacgtcaagg ctgtgaccct caccatggtg gagaacgacc     2820

atatccgtgg ggccaagagt gagatcttgt acattcgcac caatgcttca gttccttcca     2880

ttcccttgga cgttctttca gcatcgaact cctcttctca gttaatcgtg aagtggaacc     2940

ctccctctct gcccaacggc aacctgagtt actacattgt gcgctggcag cggcagcctc     3000

aggacggcta cctttaccgg cacaattact gctccaaaga caaaatcccc atcaggaagt     3060

atgccgacgg caccatcgac attgaggagg tcacagagaa ccccaagact gaggtgtgtg     3120

gtggggagaa agggccttgc tgcgcctgcc ccaaaactga agccgagaag caggccgaga     3180

aggaggaggc tgaataccgc aaagtctttg agaatttcct gcacaactcc atcttcgtgc     3240

ccagacctga aaggaagcgg agagatgtca tgcaagtggc caacaccacc atgtccagcc     3300

gaagcaggaa caccacggcc gcagacacct acaacatcac cgacccggaa gagctggaga     3360

cagagtaccc tttctttgag agcagagtgg ataacaagga gagaactgtc atttctaacc     3420

ttcggccttt cacattgtac cgcatcgata tccacagctg caaccacgag gctgagaagc     3480

tgggctgcag cgcctccaac ttcgtctttg caaggactat gcccgcagaa ggagcagatg     3540

acattcctgg gccagtgacc tgggagccaa ggcctgaaaa ctccatcttt ttaaagtggc     3600

cggaacctga gaatcccaat ggattgattc taatgtatga aataaaatac ggatcacaag     3660

ttgaggatca gcgagaatgt gtgtccagac aggaatacag gaagtatgga ggggccaagc     3720

taaaccggct aaacccgggg aactacacag cccggattca ggccacatct ctctctggga     3780

atgggtcgtg gacagatcct gtgttcttct atgtccaggc caaaacagga tatgaaaact     3840

tcatccatct gatcatcgct ctgcccgtcg ctgtcctgtt gatcgtggga gggttggtga     3900

ttatgctgta cgtcttccat agaaagagaa ataacagcag gctggggaat ggagtgctgt     3960

atgcctctgt gaacccggag tacttcagcg ctgctgatgt gtacgttcct gatgagtggg     4020

aggtggctcg ggagaagatc accatgagcc gggaacttgg gcaggggtcg tttgggatgg     4080

tctatgaagg agttgccaag ggtgtggtga aagatgaacc tgaaaccaga gtggccatta     4140

aaacagtgaa cgaggccgca agcatgcgtg agaggattga gtttctcaac gaagcttctg     4200

tgatgaagga gttcaattgt caccatgtgg tgcgattgct gggtgtggtg tcccaaggcc     4260

agccaacact ggtcatcatg gaactgatga cacggggcga tctcaaaagt tatctccggt     4320

ctctgaggcc agaaatggag aataatccag tcctagcacc tccaagcctg agcaagatga     4380

ttcagatggc cggagagatt gcagacggca tggcatacct caacgccaat aagttcgtcc     4440

acagagacct tgctgcccgg aattgcatgg tagccgaaga tttcacagtc aaaatcggag     4500

attttggtat gacgcgagat atctatgaga cagactatta ccggaaagga gggaaagggc     4560

tgctgcccgt gcgctggatg tctcctgagt ccctcaagga tggagtcttc accacttact     4620

cggacgtctg gtccttcggg gtcgtcctct gggagatcgc cacactggcc gagcagccct     4680

accagggctt gtccaacgag caagtccttc gcttcgtcat ggagggcggc cttctggaca     4740

agccagacaa ctgtcctgac atgctgtttg aactgatgcg catgtgctgg cagtataacc     4800

ccaagatgag gccttccttc ctggagatca tcagcagcat caaagaggag atggagcctg     4860

gcttccggga ggtctccttc tactacagcg aggagaacaa gctgcccgag ccggaggagc     4920

tggacctgga gccagagaac atggagagcg tccccctgga cccctcggcc tcctcgtcct     4980

ccctgccact gcccgacaga cactcaggac acaaggccga gaacggcccc ggccctgggg     5040

tgctggtcct ccgcgccagc ttcgacgaga gacagcctta cgcccacatg aacgggggcc     5100

gcaagaacga gcgggccttg ccgctgcccc agtcttcgac ctgctgatcc ttggatcctg     5160

aatctgtgca aacagtaacg tgtgcgcacg cgcagcgggg tgggggggga gagagagttt     5220

taacaatcca ttcacaagcc tcctgtacct cagtggatct tcagaactgc ccttgctgcc     5280

cgcgggagac agcttctctg cagtaaaaca catttgggat gttccttttt tcaatatgca     5340

agcagctttt tattccctgc ccaaaccctt aactgacatg ggcctttaag aaccttaatg     5400

acaacactta atagcaacag agcacttgag aaccagtctc ctcactctgt ccctgtcctt     5460

ccctgttctc cctttctctc tcctctctgc ttcataacgg aaaaataatt gccacaagtc     5520

cagctgggaa gcccttttta tcagtttgag gaagtggctg tccctgtggc cccatccaac     5580

cactgtacac acccgcctga caccgtgggt cattacaaaa aaacacgtgg agatggaaat     5640

ttttaccttt atctttcacc tttctaggga catgaaattt acaaagggcc atcgttcatc     5700

caaggctgtt accattttaa cgctgcctaa ttttgccaaa atcctgaact ttctccctca     5760

tcggcccggc gctgattcct cgtgtccgga ggcatgggtg agcatggcag ctggttgctc     5820

catttgagag acacgctggc gacacactcc gtccatccga ctgcccctgc tgtgctgctc     5880

aaggccacag gcacacaggt ctcattgctt ctgactagat tattatttgg gggaactgga     5940

cacaataggt ctttctctca gtgaaggtgg ggagaagctg aaccggcttc cctgccctgc     6000

ctccccagcc ccctgcccaa cccccaagaa tctggtggcc atgggccccg aagcagcctg     6060

gcggacaggc ttggagtcaa ggggccccat gcctgcttct ctcccagccc cagctccccc     6120

gcccgccccc aaggacacag atgggaaggg gtttccaggg actcagcccc actgttgatg     6180

caggtttgca aggaaagaaa ttcaaacacc acaacagcag taagaagaaa agcagtcaat     6240

ggattcaagc attctaagct ttgttgacat tttctctgtt cctaggactt cttcatgggt     6300

cttacagttc tatgttagac catgaaacat ttgcatacac atcgtcttta atgtcacttt     6360

tataactttt ttacggttca gatattcatc tatacgtctg tacagaaaaa aaaaagctgc     6420

tatttttttt gttcttgatc tttgtggatt taatctatga aaaccttcag gtccaccctc     6480

tcccctttct gctcactcca agaaacttct tatgctttgt actagagtgc gtgactttct     6540

tcctcttttc ccggtaatgg atacttctat cacataattt gccatgaact gttggatgcc     6600

tttttataaa tacatccccc atccctgctc ccacctgccc ctttagttgt tttctaaccc     6660

gtaggctctc tgggcacgag gcagaaagca ggccgggcac ccatcctgag agggccgcgc     6720

tcctctcccc agcctgccct cacagcattg gagcctgtta cagtgcaaga catgatacaa     6780

actcaggtca gaaaaacaaa ggttaaatat ttcacacgtc tttgttcagt gtttccactc     6840

accgtggttg agaagcctca ccctctcttt cccttgcctt tgcttaggtt gtgacacaca     6900

tatatatata tttttttaat tcttgggtac aacagcagtg ttaaccgcag acactaggca     6960

tttggattac tatttttctt aatggctatt taatccttcc atcccacgaa aaacagctgc     7020

tgagtccaag ggagcagcag agcgtggtcc ggcagggcct gttgtggccc tcgccacccc     7080

cctcaccgga ccgactgacc tgtctttgga accagaacat cccaagggaa ctccttcgca     7140

ctggcgttga gtgggacccc gggatccagg ctggcccagg gcggcaccct cagggctgtg     7200

cccgctggag tgctaggtgg aggcagcaca gacgccacgg tggcccaaga gcccctttgc     7260

ttcttgctgg gggaccaggg ctgtggtgct ggcccacttt ccctcggcca ggaatccagg     7320

tccttggggc ccaggggtct tgtcttgttt catttttagc acttctcacc agagagatga     7380

cagcacaaga gttgcttctg ggatagaaat gtttaggagt aagaacaaag ctgggatacg     7440

gtgattgcta gttgtgactg aagattcaac acagaaaaga aagtttatac ggcttttttg     7500

ctggtcagca gtttgtccca ctgctttctc tagtctctat cccatagcgt gttcccttta     7560

aaaaaaaaaa aaaggtatta tatgtaggag ttttctttta atttattttg tgataaatta     7620

ccagtttcaa tcactgtaga aaagccccat tatgaattta aatttcaagg aaagggtgtg     7680

tgtgtgtgta tgtgtggggt gtgtgtgtgt gagagtgatg ggacagttct tgattttttg     7740

ggtttttttt cccccaaaca tttatctacc tcactcttat tttttatatg tgtatataga     7800

caaaagaata catctcacct ttctcagcac ctgacaatag gccgttgata ctggtaacct     7860

catccacgcc acaggcgcca cacccaggtg atgcaggggg aagccaggct gtattccggg     7920

gtcaaagcaa cactaactca cctctctgct catttcagac agcttgcctt tttctgagat     7980

gtcctgtttt gtgttgcttt ttttgttttg ttttctatct tggtttccac caaggtgtta     8040

gatttctcct cctcctagcc aggtggccct gtgaggccaa cgagggcacc agagcacacc     8100

tgggggagcc accaggctgt ccctggctgg ttgtctttgg aacaaactgc ttctgtgcag     8160

atggaatgac caacacattt cgtccttaag agagcagtgg ttcctcaggt tctgaggaga     8220

ggaaggtgtc caggcagcac catctctgtg cgaatcccca gggtaaaggc gtggggcatt     8280

gggtttgctc cccttgctgc tgctccatcc ctgcaggagg ctcgcgctga ggcaggaccg     8340

tgcggccatg gctgctgcat tcattgagca caaaggtgca gctgcagcag cagctggaga     8400

gcaagagtca cccagcctgt gcgccagaat gcagaggctc ctgacctcac agccagtccc     8460

tgatagaaca cacgcaggag cagagtcccc tccccctcca ggctgccctc tcaacttctc     8520

cctcacctcc ttccctaggg gtagacagag atgtaccaaa ccttccggct ggaaagccca     8580

gtggccggcg ccgaggctcg tggcgtcacg ccccccccgc cagggctgta cctccgtctc     8640

cctggtcctg ctgctcacag gacagacggc tcgctcccct cttccagcag ctgctcttac     8700

aggcactgat gatttcgctg ggaagtgtgg cgggcagctt tgcctaagcg tggatggctc     8760

ctcggcaatt ccagcctaag tgaaggcgct caggagcctc ctgctggaac gcgacccatc     8820

tctcccagga ccccggggat cttaaggtca ttgagaaata ctgttggatc agggttttgt     8880

tcttccacac tgtaggtgac cccttggaat aacggcctct cctctcgtgc acatacctac     8940

cggtttccac aactggattt ctacagatca ttcagctggt tataagggtt ttgtttaaac     9000

tgtccgagtt actgatgtca ttttgttttt gttttatgta ggtagctttt aagtagaaaa     9060

cactaacagt gtagtgccca tcatagcaaa tgcttcagaa acacctcaat aaaagagaaa     9120

acttggcttg tgtgatggtg cagtcacttt actggaccaa cccacccacc ttgactatac     9180

caaggcatca tctatccaca gttctagcct aacttcatgc tgatttctct gcctcttgat     9240

ttttctctgt gtgttccaaa taatcttaag ctgagttgtg gcattttcca tgcaacctcc     9300

ttctgccagc agctcacact gcttgaagtc atatgaacca ctgaggcaca tcatggaatt     9360

gatgtgagca ttaagacgtt ctcccacaca gcccttccct gaggcagcag gagctggtgt     9420

gtactggaga cactgttgaa cttgatcaag acccagacca ccccaggtct ccttcgtggg     9480

atgtcatgac gtttgacata cctttggaac gagcctcctc cttggaagat ggaagaccgt     9540

gttcgtggcc gacctggcct ctcctggcct gtttcttaag atgcggagtc acatttcaat     9600

ggtacgaaaa gtggcttcgt aaaatagaag agcagtcact gtggaactac caaatggcga     9660

gatgctcggt gcacattggg gtgctttggg ataaaagatt tatgagccaa ctattctctg     9720

gcaccagatt ctaggccagt ttgttccact gaagcttttc ccacagcagt ccacctctgc     9780

aggctggcag ccgaatggct tgccagtggc tctgtggcaa gatcacactg agatcgatgg     9840

gtgagaaggc taggatgctt gtctagtgtt cttagctgtc acgttggctc cttccagggt     9900

ggccagacgg tgttggccac tcccttctaa aacacaggcg ccctcctggt gacagtgacc     9960

cgccgtggta tgccttggcc cattccagca gtcccagtta tgcatttcaa gtttggggtt    10020

tgttcttttc gttaatgttc ctctgtgttg tcagctgtct tcatttcctg ggctaagcag    10080

cattgggaga tgtggaccag agatccactc cttaagaacc agtggcgaaa gacactttct    10140

ttcttcactc tgaagtagct ggtggtacaa atgagaactt caagagagga tgttatttag    10200

actgaacctc tgttgccaga gatgctgaag atacagacct tggacaggtc agagggtttc    10260

atttttggcc ttcatcttag atgactggtt gcgtcatttg gagaagtgag tgctccttga    10320

tggtggaatg accgggtggt gggtacagaa ccattgtcac agggatcctg gcacagagaa    10380

gagttacgag cagcagggtg cagggcttgg aaggaatgtg ggcaaggttt tgaacttgat    10440

tgttcttgaa gctatcagac cacatcgagg ctcagcagtc atccgtgggc atttggtttc    10500

aacaaagaaa cctaacatcc tactctggaa actgatctcg gagttaaggc gaattgttca    10560

agaacacaaa ctacatcgca ctcgtcagtt gtcagttctg gggcatgact ttagcgtttt    10620

gtttctgcga gaacataacg atcactcatt tttatgtccc acgtgtgtgt gtccgcatct    10680

ttctggtcaa cattgtttta actagtcact cattagcgtt ttcaataggg ctcttaagtc    10740

cagtagatta cgggtagtca gttgacgaag atctggttta caagaactaa ttaaatgttt    10800

cattgcattt ttgtaagaac agaataattt tataaaatgt ttgtagttta taattgccga    10860

aaataattta aagacacttt ttttttctct gtgtgtgcaa atgtgtgttt gtgatccatt    10920

tttttttttt ttttttagga cacctgttta ctagctagct ttacaatatg ccaaaaaagg    10980

atttctccct gaccccatcc gtggttcacc ctcttttccc cccatgcttt ttgccctagt    11040

ttataacaaa ggaatgatga tgatttaaaa agtagttctg tatcttcagt atcttggtct    11100

tccagaaccc tctggttggg aaggggatca ttttttactg gtcatttccc tttggagtgt    11160

agctacttta acagatggaa agaacctcat tggccatgga aacagccgag gtgttggagc    11220

ccagcagtgc atggcaccgt tcggcatctg gcttgattgg tctggctgcc gtcattgtca    11280

gcacagtgcc atggacatgg gaagacttga ctgcacagcc aatggttttc atgatgatta    11340

cagcatacac agtgatcaca taaacgatga cagctatggg gcacacaggc catttgctta    11400

catgcctcgt atcatgactg attactgctt tgttagaaca cagaagagac cctattttat    11460

ttaaggcaga accccgaaga tacgtatttc caatacagaa aagaattttt aataaaaact    11520

ataacataca caaaaattgg ttttaaagtt gactccactt cctctaactc cagtggattg    11580

ttggccatgt ctccccaact ccacaatatc tctatcatgg gaaacacctg gggtttttgc    11640

gctacatagg agaaagatct ggaaactatt tgggttttgt tttcaacttt tcatttggat    11700

gtttggcgtt gcacacacac atccaccggt ggaagagacg cccggtgaaa acacctgtct    11760

gctttctaag ccagtgaggt tgaggtgaga ggtttgccag agtttgtcta cctctgggta    11820

tccctttgtc tgggataaaa aaaatcaaac cagaaggcgg gatggaatgg atgcaccgca    11880

aataatgcat tttctgagtt ttcttgttaa aaaaaaattt ttttaagtaa gaaaaaaaaa    11940

ggtaataaca tggccaattt gttacataaa atgactttct gtgtataaat tattcctaaa    12000

aaatcctgtt tatataaaaa atcagtagat gaaaaaaatt tcaaaatgtt tttgtatatt    12060

ctgttgtaag aatttattcc tgttattgcg atatactctg gattctttac ataatggaaa    12120

aaagaaactg tctattttga atggctgaag ctaaggcaac gttagtttct cttactctgc    12180

ttttttctag taaagtacta catggtttaa gttaaataaa ataattctgt atgcaaaaaa    12240

aaaaaaaaaa aaaaaaaaaa aa                                             12262


<210>  113
<211>  8769
<212>  DNA
<213>  homo sapiens

<400>  113
atttagaggc ggcgccaggg cggccgcgga gaaacgtgac acaccagccc tctcggaggg       60

gtttcggacc gaagggaaga agctgcgccg tgtcgtccgt ctccctgcgc gccgcgggca      120

cttctcctgg gctctccccg aactctcccg cgacctctgc gcgccctcag gccgccttcc      180

ccgccctggg ctcgggacaa cttctggggt ggggtgcaaa gaaagtttgc ggctcctgcc      240

gccggcctct ccgcctcttg gcctaggagg ctcgccgccc gcgcccgctc gttcggcctt      300

gcccgggacc gcgtcctgcc ccgagaccgc caccatgaac aagctttaca tcggcaacct      360

caacgagagc gtgacccccg cggacttgga gaaagtgttt gcggagcaca agatctccta      420

cagcggccag ttcttggtca aatccggcta cgccttcgtg gactgcccgg acgagcactg      480

ggcgatgaag gccatcgaaa ctttctccgg gaaagtagaa ttacaaggaa aacgcttaga      540

gattgaacat tcggtgccca aaaaacaaag gagccggaaa attcaaatcc gaaatattcc      600

accccagctc cgatgggaag tactggacag cctgctggct cagtatggta cagtagagaa      660

ctgtgagcaa gtgaacaccg agagtgagac ggcagtggtg aatgtcacct attccaaccg      720

ggagcagacc aggcaagcca tcatgaagct gaatggccac cagttggaga accatgccct      780

gaaggtctcc tacatccccg atgagcagat agcacaggga cctgagaatg ggcgccgagg      840

gggctttggc tctcggggtc agccccgcca gggctcacct gtggcagcgg gggccccagc      900

caagcagcag caagtggaca tcccccttcg gctcctggtg cccacccagt atgtgggtgc      960

cattattggc aaggaggggg ccaccatccg caacatcaca aaacagaccc agtccaagat     1020

agacgtgcat aggaaggaga acgcaggtgc agctgaaaaa gccatcagtg tgcactccac     1080

ccctgagggc tgctcctccg cttgtaagat gatcttggag attatgcata aagaggctaa     1140

ggacaccaaa acggctgacg aggttcccct gaagatcctg gcccataata actttgtagg     1200

gcgtctcatt ggcaaggaag gacggaacct gaagaaggta gagcaagata ccgagacaaa     1260

aatcaccatc tcctcgttgc aagaccttac cctttacaac cctgagagga ccatcactgt     1320

gaagggggcc atcgagaatt gttgcagggc cgagcaggaa ataatgaaga aagttcggga     1380

ggcctatgag aatgatgtgg ctgccatgag cctgcagtct cacctgatcc ctggcctgaa     1440

cctggctgct gtaggtcttt tcccagcttc atccagcgca gtcccgccgc ctcccagcag     1500

cgttactggg gctgctccct atagctcctt tatgcaggct cccgagcagg agatggtgca     1560

ggtgtttatc cccgcccagg cagtgggcgc catcatcggc aagaaggggc agcacatcaa     1620

acagctctcc cggtttgcca gcgcctccat caagattgca ccacccgaaa cacctgactc     1680

caaagttcgt atggttatca tcactggacc gccagaggcc caattcaagg ctcagggaag     1740

aatctatggc aaactcaagg aggagaactt ctttggtccc aaggaggaag tgaagctgga     1800

gacccacata cgtgtgccag catcagcagc tggccgggtc attggcaaag gtggaaaaac     1860

ggtgaacgag ttgcagaatt tgacggcagc tgaggtggta gtaccaagag accagacccc     1920

tgatgagaac gaccaggtca tcgtgaaaat catcggacat ttctatgcca gtcagatggc     1980

tcaacggaag atccgagaca tcctggccca ggttaagcag cagcatcaga agggacagag     2040

taaccaggcc caggcacgga ggaagtgacc agcccctccc tgtcccttcg agtccaggac     2100

aacaacgggc agaaatcgag agtgtgctct ccccggcagg cctgagaatg agtgggaatc     2160

cgggacacct gggccgggct gtagatcagg tttgcccact tgattgagaa agatgttcca     2220

gtgaggaacc ctgatctctc agccccaaac acccacccaa ttggcccaac actgtctgcc     2280

cctcggggtg tcagaaattc tagcgcaagg cacttttaaa cgtggattgt ttaaagaagc     2340

tctccaggcc ccaccaagag ggtggatcac acctcagtgg gaagaaaaat aaaatttcct     2400

tcaggtttta aaaacatgca gagaggtgtt ttaatcagcc ttaaaggatg gttcatttct     2460

tgaccttaat gtttttccaa tcttcttccc cctacttggg taattgatta aaatacctcc     2520

atttacggcc tctttctata tttacactaa tttttttatc tttattgcta ccagaaaaaa     2580

atgcgaacga atgcattgct ttgcttacag tattgactca agggaaaaga actgtcagta     2640

tctgtagatt aattccaatc actccctaac caataggtac aatacggaat gaagaagagg     2700

ggaaaatggg gagaaagatg gttaaaatac ataataatcc acgtttaaaa ggagcgcact     2760

tgtggctgat ctatgccaga tcaccatctt caaattggca caactgaaat ttccccactc     2820

tgttggggct tccccaccac attcatgtcc ctctcccgtg taggtttcac attatgtcca     2880

ggtgcacata ggtggtattg aatgctcagc agggtagggg ctgaccactg tccctgattc     2940

ccatcgttct caggcggatt ttatattttt ttaaagtcta ttttaatgat tggatatgag     3000

cactgggaag gggacgctaa ctccccttga taaagtctcg gttccatgga ggacttgagt     3060

ggccccaaag gctgccacgg tgccctcacc ccagcccatg tgctcccata agggctggtt     3120

cctagaggca ggggttgtgg ggcactccca gccacggcac tgttaccttg gtggtgggac     3180

ttggaaccca accctgagct cccgataaag ctaaagtcca tcatctggca aattcagtaa     3240

attggagagt acttgcttct gtttgtatct gagaggaatt tttaactgac ggcttctgtc     3300

tccatgaatc attatcagca tgatgaaagg tgtgtctaaa aaacaattca gaataccagc     3360

agcattgtac agcaaggggt aaataagctt aatttattaa tttaccaggc ttaattaaga     3420

tcccatggag tgtttagccc ttgtgggaga cagaagccat cagttaaatg aggttaggcc     3480

tctcctccta atatactgat tgacaatgca tattagccag gtaatgcact ttagctaccc     3540

tggacaatgc tatcaagtgt gctgggaagg gaggaaggcc tctctacata tggaaaagcc     3600

catgcgtgga gttcccctcc tttcaacatt gcaacaacag taacaacaag acaaccgcaa     3660

catgtgggcg tagtcaggca atgctgtgtg cgaagtaaac tacctcaagg tatgaagtta     3720

cctcagcaat tattttcctt tttgttcccc ccaaccccat taaaaaaatt tttttttgat     3780

ttttgttttt ttgcagcttg ctgatatttt atataaaaaa gaaaagcaaa gcaaaagaga     3840

agctgatagt cttgaatatt ttattttttt aatgaaaaga aaaaacaaga aagttatgtt     3900

tcataatttc ttacaacatg agccagtaac cctttaggaa ctctctatgg agaacaggcc     3960

tggtgggaaa ggctttgggg gctgccccct taggaggagg ctagtgctaa gagggaaggc     4020

ccaggtttga gagagcccag aggggcagag cccagagcct tgtttggccc tgatctctga     4080

cttctagagc cccagctgct ggcggctgct ggaatatcct acctgatagg attaaaaggc     4140

ctagtggagc tgggggctct cagtggttaa acaatgccca acaaccaacc agctggccct     4200

tggtctcctc tctttcctcc tttggttaaa gagcatctca gccagctttt cccaccagtg     4260

gtgctgttga gatattttaa aatattgcct ccgttttatc gaggagagaa ataataacta     4320

aaaaatatac cctttaaaaa aacctatatt tctctgtcta aaaatatggg agctgagatt     4380

ccgttcgtgg aaaaaagaca aggccaccct ctcgccctca gagaggtcca cctggtttgt     4440

cattgcaatg cttttcattt tttttttttg ttattgtttc atttcagttc cgtcttgcta     4500

ttcttcctaa tctatatcca tagatctaag gggcaaacag atactagtta actgccccca     4560

cctctgtctc cctgtcttct ttagatcggt ctgattgatt ttaaaagtgg acccaaactt     4620

agggaattct tgatttaggg tggctggtgg caaggagggg caggggatat ggggacgtga     4680

ctgggacagg ttcctgcctt atcattttct ccctaggaca ttcccttgta gcccccagaa     4740

ttgtctggcc caaattgaat agaagcagaa aaacatttag ggataacatc aggccagtag     4800

aattaagcct ctccacctgt cccaaccata aaaagggtct cccagctttc catctctggc     4860

tctatatgct ttatcccaaa acaaagcaga taacgttcag acgtcggcca tttagtaatt     4920

taaagcgaat ttccagcagc aagcatgctt tgatatctgg ttcagactat catcaggaag     4980

aaaaaaaaat cccacagtac ctgaaatgtg attgttgcag tgttcagttt ccttgggggc     5040

ctgctccctt cacaccttga gcccaagtcc ttttccgttg gctgattcag ctcccagaag     5100

agacgaggaa gtgtgtggca agggactgga aaacttcact tgcttggatt aggcaaggct     5160

ccactcattg ttgatatttg cccagcagga aaatcatgta agttatacca ccagaaagca     5220

aaaggagcat ggtttggtgg ttaaggttta gtgggatgaa ggacctgtct tggtgggccg     5280

ggccctcttg tgccccgtag gctaggtctt agggcaactc cttgccctcc tgctcagcac     5340

ctccatttcc ccatccttgg tgagataaca agctatcgcg aaaagcactt gggagatttg     5400

gatgatttga gaagagtgac ttaaaaaaaa tgcttctgtg ctctaagata tatatgtgtg     5460

tgtgtgtgct acatatatat ttttaagaaa ggaccatctc tttaggatat atttttaaat     5520

tctttgaaac acataaccaa aatggtttga ttcactgact gactttgaag ctgcatctgc     5580

cagttacacc ccaaatggct ttaatcccct ctcgggtctg gttgcctttt gcagtttggg     5640

ttgtggactc agctcctgtg aggggtctgg ttaggagaga gccattttta aggacaggga     5700

gttttatagc ccttttctac tttcctcccc tcctcccagt ccttatcaat cttttttcct     5760

ttttcctgac cccctccttc tggaggcagt tgggagctat ccttgtttat gcctcactat     5820

tggcagaaaa gaccccattt aaaacccaga gaacactgga gggggatgct ctagttggtt     5880

ctgtgtccat tttcctctgt gccaaagaca gacagacaga ggctgagaga ggctgttcct     5940

gaatcaaagc aatagccagc tttcgacaca tacctggctg tctgaggagg aaggcctcct     6000

ggaaactggg agctaagggc gaggcccttc ccttcagagg ctcctggggg attagggtgt     6060

ggtgtttgcc aagccaaggg gtagggagcc gagaaattgg tctgtcggct cctggttgca     6120

ctttggggaa ggagaggaag tttggggctc caggtagctc cctgttgtgg gactgctctg     6180

tcccctgccc ctactgcaga gatagcactg ccgagttccc ttcaggcctg gcagacgggc     6240

agtgaggagg ggcctcagtt agctctcaag ggtgccttcc cctcctccca acccagacat     6300

accctctgcc aaactgggaa ccagcagtgc tagtaactac ctcacagagc cccagagggc     6360

ctgcttgagc cttcttgctc cacaggagaa gctggtgcct ctaggcaacc ccttcctccc     6420

acctctcatc aggggtgggg gttctccttt ctttcccctg aagtgtttat ggggagatcc     6480

tagtggcttt gccattcaaa ccactcgact gtttgcctgt ttcttgaaaa ccagtagaag     6540

ggaaacagca cagcctgtca cagtaattgc aggaagattg aagaaaaatc ctcatcaatg     6600

ccaggggaca taaaagccat ttcccttcca aatactcgac aatttagatg cagaacattt     6660

ctctgtattc agacttagag taacaccagc tgaaaactgc agtttctttc ctttggatac     6720

ataaggcttc tctatcgggg tacgggacag ggaggaggcc tcatgtctga agggggattt     6780

aggggcgaga gccccagccc tgaccctcgg tcctgtgcac cgctttgggg cacagtctga     6840

tggcgccttt gctggcgcct tagtatggtt gactccggat ggacaaaaga aaaaaaattt     6900

tttttcttga atgaaatagc aggaagctcc tcgggagcat gtgttttgat taaccgcagg     6960

tgatggatgc tacgagtata aatggattaa ctacctcaat ccttacagta agattggaac     7020

taagggcagg gactcatgca taagggtatg aatcccagcc aggacaagtg agttgaggct     7080

tgtgccacaa aaggtttgtc cttggggaac aggcaggcct gccaggatcc cccccatatc     7140

gattgggctg ggagggctgg ccatgaggtc cccactttct gctttccttg cccatgtgtc     7200

acccctttgg cctccagctt gtccctctct cactttctat agctttgttg gaccagatgg     7260

tgaggaaagg aatggcctct tcccttctag agggggctgg ctggagtgag acctggggct     7320

tggcctggaa cccaccacac agccccaaag tcaggaagcc tggggaaacc agagctgaga     7380

cctcttcaac agggtttctt tgagatccta cacctccatt gggccctttt tcagtcttca     7440

atgggggccc agttggctct agaaggagaa gaggtgaagc aggatccttt gccctggggg     7500

agtctgaggg cgcggtcctt ggactcattc aggccgtctt tgtagttggg ggagttccac     7560

tgggcgatcc cagcccctcc ccacccaccc tctaatggac ctcctcatag aagccccatt     7620

tcacttttgt tttatctacc tcttagcaaa acaatagata aattaggtag tggcagctcc     7680

acttgcttag gttagggggg gaaaaagatt tctttttcca aaggaaaaaa atattacctt     7740

gagaatactt tccaaaaaat aaaattaaaa aaaaaaaaac caaaaaaaaa aatttttttt     7800

taaaagggag acattttcca gtgaccactg gattgtttta atttcccaag cttttttttc     7860

ccccataaat aagtttcact ctttggcgat tttcttcact tgtttaagat aacgtgctag     7920

ctattccaac aggtaacagc tttcacagtc tgcccctggc ctgtctcacc ccatccccca     7980

ccctattcct gccagtgagt ccttcctgtg cttctctccc ttctcccctc ccagccagct     8040

gacttcagtc acccctgtcc cccctcccct gccaataagc tcccccagga ataaaggctt     8100

tgttttgggg atgcttaaat cttgactggc acttcccggc tgtgggggct ggggagccac     8160

ttgtaacatt tctgtgcaga ttttatgtta gccactgcta tgtaaaagca cgttcaaaat     8220

gaatttcagc agattatgtg ttaccataat gaataaacgt cctctatcac catttggagt     8280

ctcccttttc tccaggatct tgatcctggt ccccaaaacc agagtgaatc aaaagagctt     8340

cctcccctga ggcaaagtgg atttgtaagc agttctgaaa catcacttac tcagaagagg     8400

gaacgatgta ttttgatgag tgcaaattgg gaagagctgg aggcctactg cttgggacag     8460

tttttttttt tttttttttt ttaaatatga gtgctagctt attctgtaat tgcggcaact     8520

ttgaaaattg tattttactg gaaatctgcc agccatcacc acccgatttt gattgtatcc     8580

ttcctcccat cctttaatct gttcattgct ttgggggagg tggggcagct ggctcacacg     8640

ttggagtttg ttctttgatg gatgaacgaa cactccagtt ttctttcccg tgaaggttgt     8700

ttcagccaca aaccacttca ttttgctgtt tcaatttcaa aataaaagga aacttatatt     8760

gaaagacaa                                                             8769


<210>  114
<211>  3065
<212>  DNA
<213>  homo sapiens

<400>  114
gggagcgccg gggaggcggg cggaggcggg cggaggcggg gggcggggag cccgaggggt       60

ggaagccggc ggcggccgag cggggtcagt tctctgtagt gtttgccaat gttggagccg      120

tctgcaaagt gtccccggca agaagaggct gcctaccaca aggactttag cttacttttt      180

aaagattgaa gaaaaaaaag aagacagaaa aagaagaact caaagataca caaagtaatt      240

tgaaccaagg ctcagaagtt tttggagccg tgagggatac agcagtttgg tcaatattgt      300

cttaacatgc ttcaaataaa tcagcttctc tccaagataa aatggcaaac ccaaaagaga      360

aaactgcaat gtgtctggta aatgagttag cccgtttcaa tagagtccaa ccccagtata      420

aacttctgaa tgaaagaggg cctgctcatt caaagatgtt ctcagtgcag ctgagtcttg      480

gtgagcagac atgggaatcc gaaggcagca gtataaagaa ggctcagcag gctgttgcca      540

ataaagcttt gactgaatct acgcttccca aaccagttca gaagccaccc aaaagtaatg      600

ttaacaataa cccaggcagt ataactccaa ctgtggaact gaatgggctt gctatgaaaa      660

ggggagagcc tgccatctac aggccattag atccaaagcc attcccaaat tatagagcta      720

attacaactt tcggggcatg tacaatcaga ggtatcattg cccagtgcct aagatctttt      780

atgttcagct cactgtagga aataatgaat tttttgggga aggaaagact cgacaagctg      840

ctagacacaa tgctgcaatg aaagccctcc aagcactgca gaatgaacct attccagaaa      900

gatctcctca gaatggtgaa tcaggaaagg atgtggatga tgacaaagat gcaaataagt      960

ctgagatcag cttagtgttt gaaattgctc tgaagcgaaa tatgcctgtc agttttgagg     1020

ttattaaaga aagtggacca ccacatatga aaagctttgt tactcgagtg tcagtaggag     1080

agttctctgc agaaggagaa ggaaatagca aaaaactctc caagaagcgc gctgcgacca     1140

ccgtcttaca ggagcttaaa aaacttccac ctcttcctgt ggtggaaaag ccaaaactat     1200

tttttaaaaa acgccctaaa acaatagtaa aggccggacc agaatatggc caagggatga     1260

accctattag ccgcctggcg caaattcaac aggccaaaaa ggaaaaggag ccggattatg     1320

ttttgctttc agaaagagga atgcctcgac gtcgagaatt tgtgatgcag gtgaaggtag     1380

gcaatgaagt tgctacagga acaggaccta ataaaaagat agccaaaaaa aatgctgcag     1440

aagcaatgct gttacaactt ggttataaag catccactaa tcttcaggat caacttgaga     1500

agacagggga aaacaaagga tggagtggtc caaagcctgg gtttcctgaa ccaacaaata     1560

atactccaaa aggaattctt catttgtctc ctgatgttta tcaagagatg gaagccagcc     1620

gccacaaagt aatctctggc actactctag gctatttgtc acccaaagat atgaaccaac     1680

cttcaagctc tttcttcagt atatctccca catcgaatag ttcagctaca attgccaggg     1740

aactccttat gaatggaaca tcttctacag ctgaagccat aggtttaaaa ggaagttctc     1800

ctactccccc ttgttctcca gtacaacctt caaaacaact ggaatattta gcaaggattc     1860

aaggctttca ggcagcctta agtgccttga aacaattttc tgaacaagga ctggatccaa     1920

tcgatggagc aatgaatatc gaaaaaggtt ctcttgaaaa acaagccaag catctgagag     1980

agaaagcgga caataaccag gcacccccgg gctccatcgc tcaggactgc aagaaatcaa     2040

actcggccgt ctagcagctc ccagaacccg cggctgccac cgcatcctta taaacctgtc     2100

agcacgcatg agggtgtctg tgttcaggga aatgaatgac taataccatt atttgagtct     2160

tatgtgaaga caacactatt ctaacacgag agataatata catggtactg tttattcaac     2220

tggggaaaaa taaaactttg agcatttccc ttggaactcg agatcagatc ataactcatt     2280

tgcctagagg cagcagaaat ctgatcctgc tactggagct taaaataaca agtaaagaaa     2340

agtgttagaa acaaagctaa aattttaaca tgattaataa tagagaagtt gggtttggtt     2400

ctgttgttat gattgttttg tcgtggtgct tgtgttcagt tatattctct ctctctctca     2460

tttcaaatac tgcttgacaa ttcgaaaatg aaccaatgat gtgctgtgga atgtgatggt     2520

tgtcttcata tagagtcaca tggtttctct ttttatgcag atatttataa tcttcatcct     2580

atatcagtag gaataactat aaggtgcact acaaaaagat gtatgcaaac aaacatgttt     2640

taaatcaggt cagatatctg atgaaaaata cgaactaatg ttaagagcaa gtagtttcaa     2700

catactccag gaactgagaa acaaaacaaa gcaattgtgg gttttgagct ccatatactc     2760

ttagcaagta agggggcgtc ttgcccctat atatcatctt cccggattcc actccctgtt     2820

gtgggaatcg cgcccacccc catccgtgtg ttgtagccac tcacggtttg catcaagagt     2880

gttttttgta actgcctctg gacttgggac agtgagtagg atcaaaaata aataatgtac     2940

atgacgggga agggaaaaac ctgttggagt tgcttccagc cagccacgct ccgggccagc     3000

atgttggaat ccagcgtgga gcagatgcag taaaaatgtg gttggtttct gtgtgaaaaa     3060

aaaaa                                                                 3065


<210>  115
<211>  3033
<212>  DNA
<213>  homo sapiens

<400>  115
gctttctttg tgtggctgaa gcgctagaaa tggcatattt tctttccctt cgttaaaaaa       60

tcagaccctc tttcccctct ctccccgcgg gaacacagct agggagtggg taggagcagg      120

atctgccgac gagggcagag gcggaaaatc ctcgggcgat gagctgaaga gggccgggtc      180

cgggagggat gctgggagct tgactcactc gcacaccatg tgtccctccg cgcgcagcac      240

gggggacttt tcggtgggga ttttgggcgc cgaccagacg cggcattttc ggaaaatagc      300

gccctgtgca gctgaagcgc tttgtgtgta gcggggccgc gtcagcccgg ccgggtacga      360

ggcgcctcgg gtccccgcac cacctcctgc tgccttcccg tcgccgctcc cgaagctttt      420

ccagatgtcc ctggtagatt tgggaaagaa gcttttagaa gcggcacgag caggtcaaga      480

tgatgaagtt cgtattttga tggcaaatgg agctcccttt actacagact ggctgggaac      540

ttctccactt catctagcag cacagtatgg tcattattcc accacagagg tactgctgcg      600

agctggtgtg agcagagatg ccagaaccaa agtggaccga acaccattac atatggcagc      660

ttctgagggc catgccagca tagtagaggt tttacttaag catggtgctg atgtcaatgc      720

aaaggacatg ttaaagatga cagctctcca ttgggccaca gaacacaatc atcaagaggt      780

ggtggaactt ttaatcaaat atggtgctga tgtacacacg caaagtaaat tttgtaaaac      840

tgcatttgat atttcaatag acaatggaaa tgaagattta gcagagatat tacagattgc      900

tatgcagaac caaatcaaca caaacccaga gagtcctgac actgtgacaa tacatgctgc      960

aacaccacag tttatcattg gacctggagg ggtggtgaac ctaacagatg aaacgggtgt     1020

atctgctgtt cagtttggaa actcttctac atcagtatta gctacattag ctgccttagc     1080

tgaagcatct gctccattgt ccaattcttc agaaactcca gtagtggcca cagaagaagt     1140

agttactgca gaatctgtgg atggtgccat tcagcaagta gttagttcag ggggtcagca     1200

agtcatcaca atagttacag atggaattca gcttggaaat ttgcactcta ttccaaccag     1260

tggaattggt cagcccatca ttgtgaccat gccagatgga caacaagtat taacagtacc     1320

agcaacagac attgctgaag aaactgttat aagtgaagaa ccaccagcta agagacaatg     1380

tatcgaaata attgaaaacc gggtggaatc tgcagaaata gaagagagag aagctcttca     1440

gaaacagctg gatgaagcaa atcgagaagc acaaaaatat cgacagcagc tcctaaagaa     1500

agaacaggaa gcagaggcct acagacagaa gttggaagct atgactcgtc ttcagactaa     1560

taaagaagct gtttaattga aatgaacatg tagtttgatt ttacttttgg tcaagaaaga     1620

atacaatctt gaactgtaca caacaaaggt acagccatgg gaatacagaa tgatagaaga     1680

gactacagat ggataattgg acttaagcca tgagctctga gttcttgtaa cataaaactt     1740

tactttagaa gttgtgaaat gtatttaaaa ctgaattctg taaatagttt tttttttttt     1800

acagttccaa atgagttgat aaagattgtt gaagagatcc aaaaccagaa taagccactg     1860

tttttgtgaa ttctttttga ttttagtaca aaccttaatt tctcagaaac ggaacagttt     1920

taagggtgat cgttgttggt taggccaaat gttgtgtaat aattatggtg gactgatgct     1980

ggaattactc ctgtaggtat aaacctctgt atgaagagaa gatttctccc aggaaatctt     2040

tgtacagctt taagttgtgt cagattctct gaaaacattt tttagaaagc aaaattttta     2100

tatttgttca atttcagcta tacccaagta gatttacatg tatatgaagc aaatattttt     2160

aaaaatttct gtttgtacat attctgcatg ttttataatt tcaaaatgca tcacttacat     2220

aggtatttct cccacagaaa tgatgaaagt gaccagaaaa aaacaaaaac aaaacccctt     2280

tactctgtag gtcattgaaa cgaagtaagc tggcagctgg ttttattgga atgacagtgt     2340

tctcggaagg agcagcctac aagataactt gaatttgcca attctgcaaa atctgtgctt     2400

ttttgaaaat ttaagagtgg ggacgtgaaa ctgtattctg tgccttccat catgatttcc     2460

acatgaaagc actttaaggc actgatttta agataatgtt tttggaaaac ccaatgcata     2520

tgggtttctg aaatatttta tggacttatt tctccccagg aaatgattct tacggaaaaa     2580

aattgctttt gtatgtagaa caggaacttt ttgtattaca gtgatgcaat agacatgtct     2640

aatgtaactt ctacttttcc ttttgaaagc tcagtgtctg tgctatgact tgctctcatc     2700

acaatattgt tgaattccac aatgtatgga cattaaacac tggcagactg ttcacttttt     2760

cttttttttt tttggtaaaa tattacttca aacccctttt tcttgcttta tttttcagtg     2820

ttttattgct ttatgaactg tttaaccctg aaatccctct aggttatcta tactgtataa     2880

aaaagcaatt acccttaaaa ctgtactctg gcctactttt ctattttgca attaaatatc     2940

tttttcacat atgttcattg tagacttatg tttttatcac atcttattaa cacattaaaa     3000

atgttatcct actgcaaaaa aaaaaaaaaa aaa                                  3033


<210>  116
<211>  3069
<212>  DNA
<213>  homo sapiens

<400>  116
gctttctttg tgtggctgaa gcgctagaaa tggcatattt tctttccctt cgttaaaaaa       60

tcagaccctc tttcccctct ctccccgcgg gaacacagct agggagtggg taggagcagg      120

atctgccgac gagggcagag gcggaaaatc ctcgggcgat gagctgaaga gggccgggtc      180

cgggagggat gctgggagct tgactcactc gcacaccatg tgtccctccg cgcgcagcac      240

gggggacttt tcggtgggga ttttgggcgc cgaccagacg cggcattttc ggaaaatagc      300

gccctgtgca gctgaagcgc tttgtgtgta gcggggccgc gtcagcccgg ccgggtacga      360

ggcgcctcgg gtccccgcac cacctcctgc tgccttcccg tcgccgctcc cgaagctttt      420

ccagatgtcc ctggtagatt tgggaaagaa gcttttagaa gcggcacgag caggtcaaga      480

tgatgaagtt cgtattttga tggcaaatgg agctcccttt actacagact ggctgggaac      540

ttctccactt catctagcag cacagtatgg tcattattcc accacagagg tactgctgcg      600

agctggtgtg agcagagatg ccagaaccaa agtggaccga acaccattac atatggcagc      660

ttctgagggc catgccagca tagtagaggt tttacttaag catggtgctg atgtcaatgc      720

aaaggacatg ttaaagatga cagctctcca ttgggccaca gaacacaatc atcaagaggt      780

ggtggaactt ttaatcaaat atggtgctga tgtacacacg caaagtaaat tttgtaaaac      840

tgcatttgat atttcaatag acaatggaaa tgaagattta gcagagatat tacagattgc      900

tatgcagaac caaatcaaca caaacccaga gagtcctgac actgtgacaa tacatgctgc      960

aacaccacag tttatcattg gacctggagg ggtggtgaac ctaacaggtc tggtatcttc     1020

agaaaattca tccaaggcaa cagatgaaac gggtgtatct gctgttcagt ttggaaactc     1080

ttctacatca gtattagcta cattagctgc cttagctgaa gcatctgctc cattgtccaa     1140

ttcttcagaa actccagtag tggccacaga agaagtagtt actgcagaat ctgtggatgg     1200

tgccattcag caagtagtta gttcaggggg tcagcaagtc atcacaatag ttacagatgg     1260

aattcagctt ggaaatttgc actctattcc aaccagtgga attggtcagc ccatcattgt     1320

gaccatgcca gatggacaac aagtattaac agtaccagca acagacattg ctgaagaaac     1380

tgttataagt gaagaaccac cagctaagag acaatgtatc gaaataattg aaaaccgggt     1440

ggaatctgca gaaatagaag agagagaagc tcttcagaaa cagctggatg aagcaaatcg     1500

agaagcacaa aaatatcgac agcagctcct aaagaaagaa caggaagcag aggcctacag     1560

acagaagttg gaagctatga ctcgtcttca gactaataaa gaagctgttt aattgaaatg     1620

aacatgtagt ttgattttac ttttggtcaa gaaagaatac aatcttgaac tgtacacaac     1680

aaaggtacag ccatgggaat acagaatgat agaagagact acagatggat aattggactt     1740

aagccatgag ctctgagttc ttgtaacata aaactttact ttagaagttg tgaaatgtat     1800

ttaaaactga attctgtaaa tagttttttt ttttttacag ttccaaatga gttgataaag     1860

attgttgaag agatccaaaa ccagaataag ccactgtttt tgtgaattct ttttgatttt     1920

agtacaaacc ttaatttctc agaaacggaa cagttttaag ggtgatcgtt gttggttagg     1980

ccaaatgttg tgtaataatt atggtggact gatgctggaa ttactcctgt aggtataaac     2040

ctctgtatga agagaagatt tctcccagga aatctttgta cagctttaag ttgtgtcaga     2100

ttctctgaaa acatttttta gaaagcaaaa tttttatatt tgttcaattt cagctatacc     2160

caagtagatt tacatgtata tgaagcaaat atttttaaaa atttctgttt gtacatattc     2220

tgcatgtttt ataatttcaa aatgcatcac ttacataggt atttctccca cagaaatgat     2280

gaaagtgacc agaaaaaaac aaaaacaaaa cccctttact ctgtaggtca ttgaaacgaa     2340

gtaagctggc agctggtttt attggaatga cagtgttctc ggaaggagca gcctacaaga     2400

taacttgaat ttgccaattc tgcaaaatct gtgctttttt gaaaatttaa gagtggggac     2460

gtgaaactgt attctgtgcc ttccatcatg atttccacat gaaagcactt taaggcactg     2520

attttaagat aatgtttttg gaaaacccaa tgcatatggg tttctgaaat attttatgga     2580

cttatttctc cccaggaaat gattcttacg gaaaaaaatt gcttttgtat gtagaacagg     2640

aactttttgt attacagtga tgcaatagac atgtctaatg taacttctac ttttcctttt     2700

gaaagctcag tgtctgtgct atgacttgct ctcatcacaa tattgttgaa ttccacaatg     2760

tatggacatt aaacactggc agactgttca ctttttcttt tttttttttg gtaaaatatt     2820

acttcaaacc cctttttctt gctttatttt tcagtgtttt attgctttat gaactgttta     2880

accctgaaat ccctctaggt tatctatact gtataaaaaa gcaattaccc ttaaaactgt     2940

actctggcct acttttctat tttgcaatta aatatctttt tcacatatgt tcattgtaga     3000

cttatgtttt tatcacatct tattaacaca ttaaaaatgt tatcctactg caaaaaaaaa     3060

aaaaaaaaa                                                             3069


<210>  117
<211>  5783
<212>  DNA
<213>  homo sapiens

<400>  117
gctccgggcc agcgcggcgg cggcggcggc ggcggcagca gcaggagcag ccccggctgc       60

gggtcgcgac ggcggcgggg cgccccctcc cccgtgccgg ggcgcggcgg agggatgtgg      120

ggccttgcgg gaggaaggct tttcggcatc ttctcggccc cggtgctggt ggctgtggtg      180

tgctgcgccc agagtgtgaa cgatcccggg aacatgtcct ttgtgaagga gacggtggac      240

aagctgttga aaggctacga cattcgccta agacccgact tcgggggtcc cccggtctgc      300

gtggggatga acatcgacat cgccagcatc gacatggttt ccgaagtcaa catggattat      360

accttaacca tgtattttca acaatattgg agagataaaa ggctcgccta ttctgggatc      420

cctctcaacc tcacgcttga caatcgagtg gctgaccagc tatgggtgcc cgacacatat      480

ttcttaaatg acaaaaagtc atttgtgcat ggagtgacag tgaaaaaccg catgatccgt      540

cttcaccctg atgggacagt gctgtatggg ctcagaatca ccacgacagc agcatgcatg      600

atggacctca ggagataccc cctggacgag cagaactgca ctctggaaat tgaaagctat      660

ggctacacca cggatgacat tgagttttac tggcgaggcg gggacaaggc tgttaccgga      720

gtggaaagga ttgagctccc gcagttctcc atcgtggagc accgtctggt ctcgaggaat      780

gttgtcttcg ccacaggtgc ctatcctcga ctgtcactga gctttcggtt gaagaggaac      840

attggatact tcattcttca gacttatatg ccctctatac tgataacgat tctgtcgtgg      900

gtgtccttct ggatcaatta tgatgcatct gctgctagag ttgccctcgg gatcacaact      960

gtgctgacaa tgacaaccat caacacccac cttcgggaga ccttgcccaa aatcccctat     1020

gtcaaagcca ttgacatgta ccttatgggc tgcttcgtct ttgtgttcct ggcccttctg     1080

gagtatgcct ttgtcaacta cattttcttt ggaagaggcc ctcaaaggca gaagaagctt     1140

gcagaaaaga cagccaaggc aaagaatgac cgttcaaaga gcgaaagcaa ccgggtggat     1200

gctcatggaa atattctgtt gacatcgctg gaagttcaca atgaaatgaa tgaggtctca     1260

ggcggcattg gcgataccag gaattcagca atatcctttg acaactcagg aatccagtac     1320

aggaaacaga gcatgcctcg agaagggcat gggcgattcc tgggggacag aagcctcccg     1380

cacaagaaga cccatctacg gaggaggtct tcacagctca aaattaaaat acctgatcta     1440

accgatgtga atgccataga cagatggtcc aggatcgtgt ttccattcac tttttctctt     1500

ttcaacttag tttactggct gtactatgtt aactgagtga ctgtacttga tttttcaaag     1560

acttcattta acactgagtg aaatattact ctgcctgtca agtttttata cctgtacaca     1620

cacagacaca caagcagaca cacacatata tacatacgca attgtatata tatgtgaact     1680

ttctcagcat atatataaaa tacacgtgta tatgaggatg tatgtgtata tgtttataca     1740

cacaggagtc agtgcccatg tgtatggaag acaaatacac atacatatat acattttgca     1800

gctatggaca atttaccaca ggatgcatat taaagaaagt catagttttt ttctttttta     1860

attgaaaggg acaagtatca tctaaatatt atgccttgag aatgagggcg tgaaacacaa     1920

tatcatcccc aaatgtgtct tgtattatca taagttagat gttttagttt aaaaatcaga     1980

aagacattct tagttaatct ttgaaaactc atacagtggt attgctagtt taaaatgagt     2040

cacttacttc atatcctctc gttcagttta gtaagcaaag gcttcttggc ttctctggtg     2100

atggggtttg ttttcatcgg gcatacgttt tctgcaatgg tttagtggct ggggtgagcc     2160

actggcagtg tgcttacctg ttgtctgaaa catagataga tcccacgttg atgtctgaac     2220

gaccgtcttt tgaaaactca tcgggagtga atggcatctc gttgtaagta ctctaatata     2280

cagtgtgtag tttgtttctg ttgttcactt ggagtggatc cagcttcact gtcatgtgcg     2340

aacacagtga cacgtttggc cagtgacatt tcaatcactg aaaatgtgct ctacatctcg     2400

tatggatttc taggcctgat atccaacaga aagcatagac gtctcaggtt attcgttact     2460

ctaaggtaaa accatctagg atgattttcc cccttgcagt tatgttatca ttcttataac     2520

attgtatgtt aatagaaaat atatttgcat aatatgcata tatatgtata tttaccaaga     2580

ttttgtttct tacgcttgct atcatggcag catgcgatgt catattttcc tttatgtgat     2640

gtaactactt tctgttatct agaaattaag attgaagcta aaacacttct actgttcaat     2700

ttcagaaact aagaatcatc ctcatgcctt tatttctgta tctgacatat ttcataagca     2760

catccaacta ctcctagact gactaggatt ctgcaggaac atgacccgta cacaccacgc     2820

gtcacccaac gacccatgac cgttctctga ggcaaaggag ggcaacctga cagcaaacac     2880

agtcactgtt ggttccttct gatccacagc ctcatcagta tttggacttt ttaaagctcg     2940

tagaaacaag acaaggtgca ccggtttcat agacgcaacc ttaacttact atttagatga     3000

gatctttcta aagaaaaaaa aaagagatga tatatttttt gtaaacaata tttctatcac     3060

aggcatccat aaactgaaat gactacagtt gtgcaaacag gtgtcacagt gaagttgagc     3120

atttggagaa aaaaataaaa agcaaaattt gcaggaagaa ctgctaaatt aatactttat     3180

cccaaaatgc cacgtatgcc tcaccctctc tgttctatcc aaaaccaagg accagagtgc     3240

tccaatggta ggccccagtt gtctcgatgt aggtagaggc accaccctcc ccgaggatgc     3300

gtgtggtgtg gactatcccc atgagctgac cactacttga tttttctttg gtggccgtaa     3360

caacctttaa tttgtgggca tctgcaacag ttcaaaaccc accatcagat aaaacataat     3420

ccacaaaatc tcacgctaga ggcaattacc tacttttaga cccttttccc tctttcattc     3480

ctatcttttt cctcctaatc gctgctctct ggttttattt tcatctggag actagccagg     3540

gatttctttg gctttggctt ttctctgacc attttttcca tgggtaacaa tgggggatcc     3600

taaaagttaa acagattggg aaaaaccttg ttaagtggcc ttatcattat tatcatgtta     3660

aagaaaaaaa atacatttgc aaagacctta tccctttcaa tacttcaggt atctttttct     3720

gtatccagta attaaaggtg tgaggtccac atgcagaaga gggaccccaa aatgtaaatg     3780

gatgtggaca aaaacagtca atggtctatt taagtgtata atttatacta ttcagaactg     3840

tgacattaat tctttctggg agaaaagtga tttaaaactt ttttgatgca tagttgaggt     3900

acccaaatat caaaggcaga gaccccatgg ggctccaaag agctgcagtc tccttcccaa     3960

ggttttctgg atataaattt gcatggtata gtcataatag cttttgagct ttttatatgc     4020

atttggcacc aagactggga tccacaactt tgtagacact gcgatgaagt taacatatta     4080

gctatactat aaatagtgtt tgtaactaca cacacacaca cacacacaca cacaaataca     4140

tacatatatt ctgtaaaaac aaaaaaaaac tttttaagat ccttgggtat gtgtttgctt     4200

tactccattt cagaagaaaa ttacttttct tctaacaaaa ttattttata gcttctccat     4260

ttttaaaact tgtgagagca ttgagaagag aactctgact gtgttaacag aagagagttg     4320

aattggagtc tctgttgtgt taaaatgacc tctcgttact ccacagtagt tatttgagcc     4380

agtgactgag tcgcgttgag gaattctgaa cccggacctc tgacgttgtt gggaggtggc     4440

tgttacccac acccagacct cttgagtaag gacagaaacg ttatcattgg ggatataatg     4500

agatttcttt cttaacaatt gaaagtaata aagagttaat tttctcagta gtcctgtctt     4560

tccaaaatgc gccacagggg ctcaagatct acagaagaat cttgttatga cagtttgtta     4620

ttacccatat tcagatatcc ttgagataat ggaagagccc tgctacataa ctccctacag     4680

agaaagactg atagacttga gtagtcctta aaacaagtgt tattcctgtt caccaacccc     4740

gggactgtgg aggggtttca ctgtctatac catgcgacat ccatttcccc tgaatctcaa     4800

acgaactaga aagtatgtca tgataatatt tccattagat ttggaagcta cctgtacatc     4860

tgcaatattg tgtttttaac gccagcaccc agaactttga catgttcagt cactccctga     4920

aaggcacttc tctcttgtcc aaacacagcg ttgacatttt tactgaggag atcatctcaa     4980

aggtgatgcc aaacgagtct ggggctggtt ttaaggggac aggcacattg cagttgtagg     5040

tgttcatttt cagcatctag tagataatcc attggtgttt gtcccaccat tggtgtattc     5100

taacaagaat gtgtccaact ttgaatctcc tggcttgaaa gtataaacca tcacttaatt     5160

cttattttaa ctctccacct gaaaaccagt tcatatttct ggccatttta tgtaagcaaa     5220

actgaacaat tggtgaaaca ttttgttact cttggaattg actctggctg tcagtgtgag     5280

ccattagagt aacatcgaat cttggggcaa agaactgccc aggtgaatta aatttttcca     5340

ggacactagc tagtgtgcct tggattgatt acctcttcta ctgcattgaa aggcgccatg     5400

ttttcctgaa atactaaatt cccaacacct gggtaaacaa tgaccttcca gagagtggct     5460

cccgtatgcc tctccctagg accaacccca tgaacatgtt ttgtcacgtt tgtctcatgt     5520

ttctacttca caagtcagtg agtgtgttta aggtaagtac aggattattc tagtaggaat     5580

aggcgattgc tgtcataatc aattctcatg ttgatttcat tttattgtaa agataaattt     5640

aaacccagtt ttgcttaagc acattgatgt aattttttgg tattatttga catgaaaaaa     5700

cagcaaaatt gagtgataga tacaatatga aacttgttga tgaatgaatt caaatttatt     5760

aaaaaaggag taactgacct aaa                                             5783


<210>  118
<211>  6234
<212>  DNA
<213>  homo sapiens

<400>  118
agttcagaga gaggagaggg agaaggagag aggggcagag gggaagggag agagggagag       60

cacgcgagac ggaaaggagc gcctcagagt ctctgaagca cgcaagagat aaccgattag      120

gaatttttcg ggcaactgtc acccggatag ctgtcagaga atcatcatca ccgcaactct      180

gacgtttcct acaagaagtt agagacttaa gcagtattgg catcggatgg aaatggtatg      240

catgctgctg tggaaaatat ccctgagctg aagaagtgca actatgtgtt gtgtgtgcta      300

aatgcccaga agaacccaga cccagtgggt aagagagacg aaatgtggag agaatgacta      360

acgacaaatc cgtgaatttg ttctctggag ttgctaattt gccagcccga agcaacacat      420

tttacaagga ggaaacattt tgctgcttct gatttctccc caaactggtg ctaccagatg      480

catggctttc tatgtgttgg aacaaatcat tcctaactgc agcatactgg gaaaggggaa      540

aggttgaggc aactaaccgg ctgtctccaa ataagtgatg agatataatg catcctccag      600

tccatgcacg cttcctcttg caatttgtgc atcattcctc agtggaaacc tttaaaccct      660

aaaatccagg aaaagaaaat aaatacatta tcatggacct gagggatttt tacctgttgg      720

ctgctctgat tgcctgttta aggctggatt ccgcaatagc tcaagaactt atttacacta      780

ttagagagga attgcctgaa aatgtgccca taggaaacat accaaaggat ctgaacattt      840

ctcacatcaa tgctgccaca gggaccagcg ccagccttgt ctacagactg gtttctaaag      900

ctggggatgc ccctttggtg aaagtttcca gcagcactgg ggaaattttc acaacctcca      960

acagaataga cagagaaaaa ctctgtgctg gcgcctcata tgctgaggag aatgagtgtt     1020

tctttgaact tgaggtggtg atcctcccca atgatttctt caggctgatc aaaataaaaa     1080

taattgtcaa ggataccaat gataatgccc ccatgtttcc atctcctgtc atcaatattt     1140

ccattccaga aaacactttg atcaacagcc gctttccaat tccatcagca acagatcctg     1200

acacaggctt caatggtgta cagcattatg aattgttaaa tgggcagagt gtttttggac     1260

tggatatcgt ggaaactcca gagggagaga agtggccaca actgattgtt cagcaaaact     1320

tggatagaga acagaaagat acctatgtga tgaaaatcaa agtagaggat ggaggcactc     1380

cacagaaatc cagtacggcc atactgcagg tcacagtaag tgatgtaaat gacaacaggc     1440

cagtgtttaa agagggtcaa gtggaggtgc atattccaga gaatgctccc gtaggtacct     1500

ctgtaattca gctccatgcc actgatgcag atataggcag taatgctgaa atccggtaca     1560

tttttggtgc ccaggtcgcc cctgcaacca aaagactctt tgctttaaat aatactactg     1620

ggctgattac agttcagagg tccttagata gagaggagac agccattcac aaagtgacag     1680

tgctggctag tgacggcagc tccactcctg ctcgagcaac ggttaccatc aatgtcaccg     1740

atgtaaatga taaccctcct aatatagacc tcaggtacat tataagtccc atcaatggca     1800

ccgtgtattt atctgagaaa gatcctgtca atacaaagat tgccctaatt acagtttcag     1860

ataaggacac agatgtgaat ggcaaagtga tctgttttat tgaaagagag gtcccatttc     1920

atttgaaggc ggtatatgac aaccaatatt tgttagagac ctcttctttg ttggactatg     1980

agggcaccaa agaattcagc tttaaaattg ttgcctctga ttctgggaag cccagtttaa     2040

atcagactgc cctggtaagg gttaagcttg aggatgaaaa tgacaaccca ccaattttca     2100

accagcctgt aattgagctg tcagtttctg aaaacaaccg acgtgggtta tacttaacaa     2160

ctattagtgc cacagatgaa gacagtggga aaaatgcaga cattgtttat cagcttggac     2220

cgaatgcctc cttctttgat ctggaccgaa aaacaggagt tttgacagcc tccagagtat     2280

ttgacagaga agaacaagaa cgattcattt ttacagtaac tgccagggac aatgggaccc     2340

ctcccctcca aagccaagcg gctgtgattg ttactgttct ggatgagaat gacaatagcc     2400

ccaagtttac tcataatcat tttcaatttt ttgtgtctga gaatctgcca aagtatagta     2460

ctgtgggggt aatcacagtg acagatgcag atgctggaga gaataaagct gtgactcttt     2520

ccattctaaa tgacaatgat aattttgtgt tggatcccta ttctggagtc ataaagtcaa     2580

atgtctcatt tgatagagag cagcagagtt cctacacttt tgatgtcaaa gccactgatg     2640

gaggacaacc acctcgttcc tctactgcaa aagtaactat caacgtcatg gatgtcaatg     2700

acaacagccc agttgtcatt tctccaccgt ctaatacttc ctttaagttg gtgcccctct     2760

cagccattcc tggctccgtg gtagcagaag tttttgcagt ggatgttgac actggaatga     2820

acgctgaact aaagtatact atagtgagtg gaaacaataa aggcttattc cggattgatc     2880

cagtaacagg taacattact ctggaagaaa aaccagcacc tactgatgtg ggattgcatc     2940

gtttggtggt caacataagt gacctggggt accctaagtc tttgcacacg cttgtgcttg     3000

tattccttta tgttaacgac actgctggaa atgcctccta tatctatgac ttgatccgca     3060

ggactatgga gaccccgttg gacaggaaca taggggatag tagccaaccc tatcaaaatg     3120

aggactatct aaccatcatg attgccatca tcgccggtgc catggtggtc attgttgtga     3180

tcttcgtcac cgttctggtg cgctgtcgcc atgcatcaag gttcaaagca gctcagagga     3240

gcaagcaagg tgccgaatgg atgtccccaa accaggagaa caagcaaaac aagaaaaaga     3300

aaagaaagaa aaggaagtct cccaaaagct ctcttttgaa ctttgttact atcgaagagt     3360

ccaaacccga tgatgcagtt catgaaccta tcaatgggac aataagcctg ccggctgaac     3420

tggaggagca aagtatagga agatttgact ggggcccggc acctccaaca acattcaagc     3480

ctaacagtcc tgacctggcc aagcactaca aatctgcttc tccacagcct gcttttcatc     3540

tcaaaccaga cactccagtt tccgtgaaaa agcaccacgt gattcaggaa ctccctttgg     3600

acaacacctt tgttgggggt tgtgacaccc tttctaaacg ctcttccact agttcagatc     3660

acttcagtgc ctcagagtgc agttcccaag gaggcttcaa gacaaagggc cccttacaca     3720

ccagacagtg taactcacac agcaaaagtg acaatattcc tgtcactcct cagaaatgtc     3780

ccagctccac gggtttccac attcaggaga atgaagaaag ccattacgag tcgcagcgcc     3840

gtgttacgtt tcatctccct gatggctccc aggaaagctg cagtgacagt ggtctaggag     3900

accatgagcc ggtgggtagt ggaaccctga tctcacaccc tcttcctctg gttcagccac     3960

aggacgaatt ctatgaccag gcctctccgg acaagaggac tgaagcagat ggcaactctg     4020

atcccaactc tgatgggcct ttgggtcccc gaggattagc tgaagctaca gagatgtgca     4080

ctcaagagtg cttggttttg ggtcactctg ataattgctg gatgcctcct ggcttgggtc     4140

catatcaaca ccccaaatct cctctctcaa cctttgcacc ccagaaagaa tgggtgaaga     4200

aggacaagct tgtgaatggg cacaccctga ccagagcctg gaaagaagac agcaacagga     4260

accagttcaa tgaccgtaag cagtatggct ccaatgaagg ccatttcaac aatggcagcc     4320

acatgacaga cattcctctg gcaaatctga agtcttataa gcaagcagga ggtgctactg     4380

agagtcctaa ggagcaccaa ctctaagaaa aggctatatg ggacctaata actttaaata     4440

gacatgctaa taccgtgtgc gtcagagctt tatgtattca atagatctct acaactatgc     4500

cccttctagc agggatacct ataactttgt gttagcacca tggagaatac aatgtttttg     4560

caacatatga gagaagatag ttctagccat gcaattttgt ttactagaat tgattacact     4620

ctccagagat ctctccattg tgcaaatttt ttttattatt gcattttatt ttgaccctgg     4680

actgctgcta tgaacaatag aatatgcatt tggaaagtaa gaaagtttca tggattagag     4740

tgactgaaaa acatatccag ttagaaaatt gtgctttttt tttttttttt tttttttttt     4800

gtcattgatt tgtgctggga ctgctatact tgacattata ctgcaaacaa aacttaaaga     4860

gataagcatt aaacctattg tgctgttaac aacgttagtg gacacttgta agtcaatcag     4920

tgttaaagta tttgtaaata gaagcaagct attattaaca acttttgtgt acttataatg     4980

ttcacctaaa aatgttgtag cataattctg tgttttatgg ttgcttctgt ccttcttttt     5040

atttacctct ttgttgttat ttttgttgtt tctttcagtg aggtgtttct gtgttagtag     5100

tctgtcttga cacacattgt tcaaacaatc tcaagcactt gtgtttaaaa aaggttctga     5160

aatcttgctt ctcatatgat agcttatgat gccggaattc tgtaaacaat aaagatgaaa     5220

gaaaaaatga aaactttata caaaaaagga cttctgcaaa agcttggaaa ttcagaacct     5280

attttttatc atcttatttt caaagtaggc aaaagcaaaa tcacttaatt agtaccatta     5340

agtgagagag taatggaaaa ctgttatcca tcaaaagtga tataatatcc tgtacttgtc     5400

actcatgtaa aactaatgta tcaaaattag catatatgga agaaaaatca ctattcaaaa     5460

atagtttcaa ttgggcaaat gtgtgtctac aactttgttg aaatggcaga gtctgtgttg     5520

atcctcatat acaataatgt tgttgtaaca caagtgttat tagaccatag ccacaaaata     5580

tttaatgtgt tgtgccttca tgatgtaaca gaacattctc caggtagggt agttggggga     5640

aataaaggga taaatctcta attattgctg tttaactgtt tgttatcata gttggtcaat     5700

gcctggcagg taccagcata ttgtcactta ggtcaaacca ataaagtgac aactaatgtt     5760

aataagatct cagttgcacg tgcaaacaaa tccaaattcg aacattctta ggaggttttt     5820

gttaaggcat gacagatgat ttaaacaaat aaatagcatg caacaaaatg tctttattga     5880

aagaagtgga agttatctta atgccacggt tcaccatcaa tttaaaagta aaaaaaacaa     5940

aaaaaaaaca aaaaatttaa aaaaaaggtt tgctaatctg atagttaatt tgttcttacc     6000

aaaaaataaa attactttgt aaatagcagt tcacattttt ccacagtata atggaaaata     6060

atgggtaggg gtgcattgct tattgaagta catttttgtc ggtttgtgag gggtgtttga     6120

tgactttgac agaataaata tctaaacaat tatccttgtt actgctttgc cagttctacg     6180

ttatttacaa ttattcagct cttgcaataa atgttctgaa ttcctgaaaa aaaa           6234


<210>  119
<211>  7753
<212>  DNA
<213>  homo sapiens

<400>  119
cgcgtccatt tgaacgtctc gcacgccttc ctgccattag cactcgagcc cgctgctgtt       60

gcccgttctt cctccagaat aggggaggga gagggaatga gaagctgctg cggcccaaga      120

gtcactgtga aggaccccgc cgctgccctc gggcctcctc ggcccctgcg cctccgggga      180

gcagccgggg ctcgccgcgc ctgacgcgtc ccgagttata cagaaataat gttgatattt      240

ggaacccatg tcgaacttct atgaagaaag gacaacgatg attgcagcaa gggatttgca      300

ggaatttgtt ccttttggtc gagaccactg caagcaccac cctaatgctt tgaaccttca      360

acttcgccag ctgcagccag cttctgaatt atggtcttct gatggtgctg ctggcttggt      420

gggatccctt caggaggtta caatccacga gaaacagaag gaaagctggc agttaaggaa      480

aggagtaagt gaaattggag aagatgtgga ctatgatgag gaactctatg ttgctggaaa      540

tatggtgata tggagcaaag gaagtaaaag ccaggcattg gcagtttata aagcatttac      600

agttgacagt cctgttcagc aggcattgtg gtgtgacttc attatatcac aggataagtc      660

tgaaaaggcc tacagtagca atgaagtaga aaaatgcata tgtatattgc aaagctcatg      720

tattaacatg catagcatag aaggaaagga ttacatagct tcattaccat ttcaggttgc      780

aaatgtttgg cccactaaat atggattgct gtttgaacga agcgcttctt cacatgaagt      840

acctccaggt tcacccagag aacctttacc tactatgttc agcatgctgc acccactaga      900

tgaaataact ccacttgttt gtaaatctgg aagtcttttt ggttcatcac gggtgcaata      960

tgttgtagat catgcaatga aaattgtttt cctcaatact gacccctcta ttgtaatgac     1020

ttatgatgct gttcaaaatg tgcattctgt gtggactctc cggagagtca aatcagagga     1080

agagaatgtt gttttaaagt tctctgaaca ggggggaacc ccacagaatg tggccactag     1140

cagctccctc acagcacatc tcagaagcct ctccaaagga gattcccctg tgacttcacc     1200

tttccagaat tactcctcca ttcacagcca gagtcgctca acctcatcac ccagtctaca     1260

ttctcgctca ccttctattt ccaacatggc agctctaagt cgtgctcatt ctcctgcgtt     1320

aggagtgcac tctttttcag gggtgcaaag gttcaacatt tcaagccata atcagtctcc     1380

aaagagacat agtatttctc attctccaaa tagtaattct aatggctcct ttcttgcacc     1440

agaaacggag ccaattgttc ctgaactgtg tattgaccat ttgtggacag aaacgattac     1500

taatataaga gagaaaaatt cacaagcctc aaaagtgttt attacatctg acctatgtgg     1560

gcaaaagttc ctgtgctttt tagtagagtc ccagctccag ttacgctgtg taaagtttca     1620

agagagtaat gataaaaccc agctcatctt tggttcagtg accaacatac cagcaaagga     1680

tgcagcacca gtggagaaaa tagacaccat gctggtcttg gaaggcagtg gaaacctggt     1740

gctatacaca ggagtggttc gggtgggaaa ggtttttatt cctggactgc cagctccctc     1800

tctgacgatg tccaacacaa tgcctcggcc cagtactcca ctagatggcg ttagtactcc     1860

aaagcctctt agtaaactcc ttggatcatt ggacgaggtt gttctgttgt ccccagttcc     1920

agaactgagg gattcttcaa aacttcatga ttctctctat aatgaggatt gtactttcca     1980

acagcttgga acttacattc attctatcag agatcctgtc cataacagag tcaccctgga     2040

actgagtaat ggctccatgg ttaggatcac tattcctgaa attgccacct ctgagttagt     2100

acaaacgtgt ttgcaagcaa ttaagtttat cctgccaaaa gaaatagcag ttcagatgct     2160

tgtcaagtgg tacaatgtcc acagtgctcc aggaggaccc agttatcact cagagtggaa     2220

tttatttgtg acttgtctca tgaacatgat gggttataac acagaccgct tagcatggac     2280

tagaaatttt gactttgaag gatcactttc tcctgtcatt gcgcccaaaa aagcaaggcc     2340

ttccgagact ggatctgatg atgactggga atatttacta aattcagact accaccagaa     2400

tgttgagtct catcttttga acagatcttt atgtctgagt ccttcagaag cttcacagat     2460

gaaggatgag gatttttcac agaatctcag tctggattct tctacacttc tctttactca     2520

catacctgca atttttttcg ttcttcacct tgtgtatgag gagcttaagt tgaatactct     2580

aatgggagaa ggaatttgtt cacttgttga acttctcgtt cagttggcaa gggacttaaa     2640

attggggcct tatgtagatc attactatag agactaccca acgcttgtca gaactactgg     2700

acaagtgtgc acaattgatc caggtcaaac aggatttatg catcatccat cattttttac     2760

gtctgagcca ccaagtattt atcagtgggt gagttcttgt ctgaagggtg aaggaatgcc     2820

accttatcct tacctccctg gaatctgtga aagaagcaga cttgtagtct tgagtattgc     2880

actgtacata cttggtgatg agagcttggt ttctgatgaa tcctcacagt atttaaccag     2940

aataactata gccccccaga agttgcaagt agaacaagag gaaaacaggt ttagtttcag     3000

gcattctaca tctgtttcta gtctagctga aagattggtt gtctggatga ctaatgtagg     3060

attcacttta agagatttgg aaactcttcc ctttggaatt gctcttccca tcagagatgc     3120

aatttatcac tgtcgtgagc agcctgcctc agactggcca gaagctgtct gtctcttgat     3180

tggacgtcag gatctttcca agcaggcctg cgaaggaaac ttacccaaag ggaagtctgt     3240

gctctcatca gatgttcctt caggaacaga aactgaggag gaagatgacg gcatgaatga     3300

catgaatcac gaggtcatgt cattaatatg gagtgaagat ttaagggtgc aggatgtgcg     3360

aaggcttctt cagagtgcgc atcctgtccg tgtcaacgta gtgcagtacc cagagctcag     3420

tgaccacgag ttcatcgagg aaaaggaaaa cagattgctc caattgtgtc agcgaactat     3480

ggctcttcct gtaggacgag gaatgtttac cttgttttcg taccatcctg ttccaacaga     3540

gccattgcct attcctaaat tgaatctgac tgggcgtgcc cctcctcgga acacaacagt     3600

agaccttaat agtggaaaca tcgatgtgcc tcccaacatg acaagctggg ccagctttca     3660

taatggtgtg gctgctggcc tgaagatagc tcctgcctcc cagatcgact cagcttggat     3720

tgtttacaat aagcccaagc atgctgagtt ggccaatgag tatgctggct ttctcatggc     3780

tctgggtttg aatgggcacc ttaccaagct ggcgactctc aatatccatg actacttgac     3840

caagggccat gaaatgacaa gcattggact gctacttggt gtttctgctg caaaactagg     3900

caccatggat atgtctatta ctcggcttct tagcattcac attcctgctc tcttaccccc     3960

aacgtccaca gagctggatg ttcctcacaa tgtccaagtg gctgcagtgg ttggcattgg     4020

ccttgtatat caagggacag ctcacagaca tactgcagaa gtcctgttgg ctgagatagg     4080

acggcctcct ggtcctgaaa tggaatactg cactgacaga gagtcatact ccttagctgc     4140

tggcttggcc ctgggcatgg tctgcttggg gcatggcagc aatttgatag gtatgtctga     4200

tctcaatgtg cctgagcagc tctatcagta catggttgga ggacataggc gctttcaaac     4260

aggaatgcat agggagaaac ataaatcacc aagttatcaa atcaaagaag gagataccat     4320

aaatgtggat gtgacttgtc caggtgctac tctagctttg gctatgatct acttaaaaac     4380

caataacaga tctattgcag attggctccg agcccctgac accatgtatt tgttggactt     4440

tgtgaagcca gaatttctct tgcttaggac acttgctcga tgcctgattt tgtgggatga     4500

tattttacca aattccaagt gggttgacag caatgttcct caaattataa gagaaaatag     4560

tatctctctc agtgaaatcg aattgccgtg ctcagaggat ttgaatttgg aaactttgtc     4620

ccaagcacat gtctacataa ttgcaggagc ctgcttgtct ctgggttttc gatttgctgg     4680

ctcagaaaac ttatcagcat ttaactgttt gcataaattt gccaaagatt ttatgactta     4740

tttgtccgca cctaatgctt ctgttacagg tcctcataac ctagaaactt gtctgagcgt     4800

ggtgctgctg tctctcgcca tggtcatggc tggctcagga aacctaaagg ttttgcagct     4860

ttgtcgcttc ttacacatga aaacgggtgg tgaaatgaac tatggttttc acttagccca     4920

ccacatggcc cttggacttc tatttttggg aggaggaagg tactctttga gcacatcaaa     4980

ttcttccatt gccgctcttc tctgtgccct ttatccgcac ttcccagctc acagcactga     5040

caaccggtat catctccagg ctctccggca cctctatgtg ctggccgcgg agcccaggct     5100

tctagtgcct gtggatgtgg acacaaacac gccctgctat gccctcttag aagttaccta     5160

caagggcact cagtggtatg aacaaaccaa agaagaattg atggctccta cccttcttcc     5220

agaactccat cttttaaagc agattaaagt aaaaggccca agatactggg aactgctcat     5280

agatttaagc aaaggaacac aacacttgaa gtccatcctt tccaaggatg gggttttata     5340

tgttaaactc cgggcgggtc agctctccta caaagaagat ccaatgggat ggcaaagttt     5400

gttggctcag actgttgcta acaggaactc tgaagcccgg gctttcaagc cagaaacaat     5460

ctcagcattc acttctgatc cagcacttct gtcatttgct gaatatttct gcaagccaac     5520

tgtgaacatg ggtcagaaac aggaaattct ggatctcttt tcttcagtac tctatgaatg     5580

tgttacccag gagaccccag agatgttgcc tgcatacata gcaatggatc aggctataag     5640

aagacttggg agaagagaaa tgtctgagac ttctgaactt tggcagataa agttggtgtt     5700

agagtttttc agctcccgaa gccatcagga gcggctgcag aaccacccta agcgggggct     5760

ctttatgaac tcggaattcc tccctgttgt gaagtgcacc attgataata ccctggacca     5820

gtggctacaa gtcgggggtg atatgtgtgt gcacgcctac ctcagcgggc agcccttgga     5880

ggaatcacag ctgagcatgc tggcctgctt cctcgtctac cactctgtgc cagctccaca     5940

gcacctgcca cctataggac tagaagggag cacaagcttt gctgaactgc tcttcaaatt     6000

taagcagcta aaaatgccag tgcgagcttt gctgagattg gctcctttgc ttcttggaaa     6060

tccacagcca atggtgatgt gaccgtgtct ggcggtgaac ctaccctgaa acgtgacttc     6120

tgcacaacaa acgtgaccaa acatcaaagc taaagcaatg tttataaagt tttatggtat     6180

aactaggggg aaatgagctg cacaaacctc aatgtatttt aaatctgttg ctgtcatcat     6240

taacggtata tgacatataa aagcaagtta aaatttactt ttgtaaataa agtttttggt     6300

ttgtttccaa aactcttgat gattgcttta gttttggact tagagaatag agcaggggtt     6360

gctggagtga atattgattt ttaaagtctt tgaactgtgg tggtataggt gaagtgacta     6420

tgcccaaaaa tgccaagttt taaaagaagc tatgtcataa agttttactt tctgtggcaa     6480

aagagcgctt tagcatttcc tcagatgtca cagttgtcct gtctaaaata agtttgtact     6540

tctggtgaca atgccagaca ctcttatgat gtgatcacct taaacaggag aaggagattt     6600

ttgccctcag ttgctcaaca tgaagtactg tggactgaat tgtgtcctcc cagaattata     6660

tattgaggcc ctaatccctg tgtgactgta ttaggcaata gggcatatag gagattacta     6720

aggttaagtg aggtcatcat aagggtgggg ccttaattca gtagaattgg tggcctccta     6780

agcagaggaa gagagatttt tctttctctc tctgccatgt gaagacagtg aggagtcggc     6840

cgtctgcaag ccaagaagag cccttatcag gaacagactt ggctagcacc ttcatcgtgg     6900

acctccagcc tccagaattg caagaaaata catttccgtc gttgaaacca cccagtctgt     6960

ggtattttgt tatggcagcc caggcagact aatacgtgaa gcctgctcta aatagataaa     7020

ataagaaatt actacagagg gctctttaga aattgtattt aaaaacaaga caatccatat     7080

ttacctaaga tttacagaat gtatgtctat aaaaggaggg atttctggac tagatgatga     7140

tgaaaaatgt tcatataaag gcacctccag cttcgagttg ccaacacagg aggaagaatg     7200

ctccctgctg ttcagatgct gatatgtgtc ctgtgcttcc tggatggcca gtgggatcat     7260

aagctggtag aagcaagacc ttcatccact gacttcatat ttcttccaca tcctgaactg     7320

tggtgtttga ctttaaaaat aaattaaagc aaatagaaat gtttccattg agattttggc     7380

aaaaacccac atgacatttg cgtctgcaga gtagacttgg aaggcatgca cctggaggcc     7440

aagtggtatt ctctggactc tctgtccttg catttgcgtg gctgccccga ggactcgctt     7500

cttcctggat gtgaagcaga ggcacgatgg ggctgactga gaggctgaaa tgtgcttctc     7560

ttcacagtta catagttttc ttctaattaa aaataaattt taagtggtag attatgaaaa     7620

ttccatttga atcaagattt taaaaattca atatcaaacc agttgttact gtcttcactc     7680

tccgttgttt acgattgtgt gcttttcctg aataaagaat gactggagag acattaaaaa     7740

aaaaaaaaaa aaa                                                        7753


<210>  120
<211>  14243
<212>  DNA
<213>  homo sapiens

<400>  120
ctcctcctcc tgctttcctc cagtaagtgc atacccgcta gtggtctgta caggcggcac       60

ggtttgatgg cagagatatt ttctttccaa actgttcaaa atgatgaacg aagatgcagc      120

tcagaaaagc gacagtggag agaagttcaa cggcagtagt cagaggagaa aaagacccaa      180

gaagtctgac agcaatgcaa gcttcctccg tgctgccaga gcaggcaacc tggacaaagt      240

tgtggaatat ctgaaggggg gcatagacat caatacctgc aatcagaatg gactcaacgc      300

tctccatctg gctgccaagg aaggccacgt ggggctggtg caggagctgc tgggaagagg      360

gtcctctgtg gattctgcca ctaagaaggg aaataccgct cttcacattg catctttggc      420

tggacaagca gaagttgtca aagttcttgt taaggaagga gccaatatta atgcacagtc      480

tcagaatggc tttactcctt tatacatggc tgcccaagag aatcacattg atgttgtaaa      540

atatttgctg gaaaatggag ctaatcagag cactgctaca gaggatggct ttactcctct      600

agctgtggca ctccagcaag gacacaacca ggcggtggcc atcctcttgg agaatgacac      660

caaagggaaa gtgaggctgc cagctctgca tattgccgct aggaaagacg acaccaaatc      720

tgccgcactt ctgcttcaga atgaccacaa tgctgacgta caatccaaga tgatggtgaa      780

taggacaact gagagtggtt ttaccccttt gcacatagct gcacattacg gaaatgtcaa      840

cgtggcaact cttcttctaa accggggagc tgctgtggac ttcacagcca ggaatggaat      900

cactcctctg catgtggctt ccaaaagagg aaatacaaac atggtgaagc tcttactgga      960

tcgaggcggt cagatcgatg ccaaaactag ggatgggttg acaccacttc actgtgctgc     1020

acgaagtggg catgaccaag tggtggaact tctgttggaa cggggtgccc ccttgctggc     1080

aaggactaag aatgggctgt ctccactaca catggctgcc cagggagacc acgtggaatg     1140

tgtgaagcac ctgttacagc acaaggcacc tgttgatgat gtcaccctag actacctgac     1200

agccctccac gttgctgcgc actgtggcca ctaccgtgta accaaactcc ttttagacaa     1260

gagagccaat ccgaacgcca gagccctgaa tggttttact ccactgcaca ttgcctgcaa     1320

gaaaaaccgc atcaaagtca tggaactgct ggtgaaatat ggggcttcaa tccaagctat     1380

aacagagtct ggcctcacac caatacatgt ggctgccttc atgggccact tgaacattgt     1440

cctccttctg ctgcagaacg gagcctctcc agatgtcact aacattcgtg gtgagacggc     1500

actacacatg gcagcccgag ccgggcaggt ggaagtggtc cgatgcctcc tgagaaatgg     1560

tgcccttgtt gatgccagag ccagggagga acagacacct ttacatattg cctcccgcct     1620

gggtaagaca gaaattgtcc agctgcttct acaacatatg gctcatccag atgcggccac     1680

tacaaatggg tacacaccac tgcacatctc tgcccgggag ggccaggtgg atgtggcatc     1740

agtcctattg gaagcaggag cagcccactc cttagctacc aagaagggtt ttactcccct     1800

gcatgtagca gccaagtatg gaagcctgga tgtggcaaaa cttctcttgc aacgccgtgc     1860

tgccgcagat tctgcaggga agaacggcct taccccgctc catgttgctg ctcattatga     1920

caaccagaag gtggcgctgc tgttactgga gaagggtgct tcccctcatg ccactgccaa     1980

gaatggctat actccgttac atattgctgc caagaagaat caaatgcaga tagcttccac     2040

actcctgaac tatggagcag agacaaacat tgtgacaaag caaggagtaa ctccactcca     2100

tctggcctcg caggaggggc acacagatat ggttaccttg cttctggata agggagccaa     2160

tatccacatg tcaactaaga gtggactcac atccttacac cttgcagccc aggaagataa     2220

agtgaatgtt gctgatattc tcaccaagca tggagctgat caggatgctc atacaaagct     2280

tggttacaca cctttaattg tggcctgtca ctatggaaat gtgaaaatgg tcaactttct     2340

tctgaagcag ggagcaaatg ttaacgcaaa aaccaagaac ggctacacgc ctttgcacca     2400

ggccgctcag cagggtcaca cgcacatcat caacgtcctg ctccagcatg gggccaagcc     2460

caacgccacc actgcgaatg gcaacactgc cttggcgatt gctaagcgtc tgggctacat     2520

ctccgtggtc gacaccctga aggttgtgac tgaggaggtc accaccacca ccacaactat     2580

tacagaaaaa cacaaactaa atgtacctga gacgatgact gaggttcttg atgtttctga     2640

tgaagagggt gatgacacaa tgactggtga tgggggagaa taccttaggc ctgaggacct     2700

aaaagaactg ggtgatgact cactacccag cagtcagttc ctggatggta tgaattacct     2760

gcgatacagc ttggagggag gacgatctga cagccttcga tccttcagtt ccgacaggtc     2820

tcacactctg agccatgcct cctacctgag ggacagtgcc gtgatggatg actcagttgt     2880

gattcccagt caccaggtgt caactctagc caaggaggca gaaaggaatt cttatcgcct     2940

aagctggggc actgagaact tagacaacgt ggctctttct tctagtccta ttcattcagg     3000

tttcctggtt agttttatgg tggatgcccg aggtggtgct atgcgaggat gcagacacaa     3060

tgggctccga atcattattc cacctcggaa atgtactgct ccaacgcgag tcacctgccg     3120

actggtcaag cgccacagac tggcaacaat gcctccaatg gtggaaggag aaggcctggc     3180

cagtcgcctg atcgaagttg gaccttctgg tgctcagttc cttggtaaac ttcacctgcc     3240

aacggctcct cccccactta atgagggaga aagtttggtc agccgcattc ttcagctggg     3300

gcctcctgga accaaattcc ttgggcctgt gatcgtggag atccctcact ttgcggccct     3360

tcgaggaaag gaaagggaac tggtggtcct gcgcagtgag aatggggaca gctggaaaga     3420

gcatttctgt gactacactg aagatgaatt gaatgaaatt cttaacggca tggatgaagt     3480

actggatagc ccagaagacc tagaaaagaa acgaatctgc cgcatcatca cccgagactt     3540

cccacagtac tttgcagtgg tgtctcgtat caaacaggac agcaatctga ttggcccaga     3600

aggaggtgta ctgagcagca cagtggtgcc ccaggtgcag gccgtcttcc cagagggggc     3660

actcaccaag cggatccgcg taggcctgca ggctcaacct atgcacagtg agctggttaa     3720

gaagatccta ggcaacaaag ctaccttcag ccctatagtc actttggaac ctagaagaag     3780

aaaattccac aaaccaatta ccatgaccat tcctgtcccc aaagcttcaa gtgatgtcat     3840

gttgaatggt tttgggggag atgcaccaac cttaagatta ctatgcagca taacaggtgg     3900

aaccacccct gcccagtggg aagatattac aggaactacg ccattaacat ttgtcaatga     3960

atgtgtttcc tttacaacaa acgtgtctgc caggttctgg ctgatagatt gtcgacagat     4020

ccaggaatcc gttacttttg catcacaagt atacagagaa attatctgcg taccttatat     4080

ggccaaattt gtagtgtttg ccaaatcaca tgaccccatt gaagccaggt tgaggtgttt     4140

ctgcatgact gatgataaag tggataagac ccttgaacaa caagaaaatt ttgctgaggt     4200

ggccagaagc agggatgtgg aggtgttaga aggaaaaccc atctacgttg attgtttcgg     4260

caacttggta ccattaacta aaagtggcca gcatcatata ttcagttttt ttgccttcaa     4320

agaaaataga cttcctctat ttgtcaaggt acgcgatacg actcaggaac cttgcggacg     4380

actatcattt atgaaggagc caaaatccac gagaggcctg gtgcatcaag ctatttgcaa     4440

cttaaacatc actttgccga tttatacaaa ggaatcagag tcagatcaag aacaggagga     4500

agagatcgat atgacatcag aaaaaaatga tgagacagaa tctacagaaa catctgtcct     4560

gaaaagtcac ctggttaatg aagttcctgt cctagcaagt ccggacttgc tctctgaagt     4620

ttctgagatg aaacaagatt tgatcaaaat gaccgccatc ttgaccacag atgtgtctga     4680

taaggcaggt tctattaaag tgaaggagct ggtgaaggct gctgaggaag agccaggaga     4740

gccttttgaa atcgttgaaa gagttaaaga ggacttagag aaagtgaatg aaatcctgag     4800

aagtggaacc tgcacaagag atgaaagcag tgtgcagagc tctcggtctg agagaggatt     4860

agttgaagag gaatgggtta ttgtcagtga tgaggaaata gaagaggcta ggcaaaaagc     4920

acctttagaa atcactgaat atccatgtgt agaagttaga atagataaag agatcaaagg     4980

aaaagtagag aaagactcaa ctgggctagt gaactacctt actgatgatc tgaatacctg     5040

tgtgcctctt cccaaagagc agctgcagac agttcaagat aaggcaggga agaaatgtga     5100

ggctctggct gttggcagga gctctgaaaa ggaagggaaa gacatacccc cagatgagac     5160

acagagtaca cagaaacagc acaaaccaag cttgggaata aagaagccag taagaaggaa     5220

attaaaagaa aagcagaaac aaaaagagga aggtttacaa gctagtgcag agaaagctga     5280

acttaaaaaa ggtagttcag aagagtcatt aggtgaagac ccaggtttag cccctgaacc     5340

ccttcccact gtcaaggcca catctccttt gatagaagaa actcccattg gttccataaa     5400

ggacaaagta aaggcccttc agaagcgagt ggaagatgaa cagaaaggtc gaagcaagtt     5460

gcccatcaga gtcaaaggca aggaggacgt gccaaaaaag accacccaca ggccacatcc     5520

agctgcgtca ccctctctga agtcagagag acatgcgcca gggtctccct cccctaaaac     5580

agaaagacac tctactcttt cctcttccgc aaaaactgaa aggcaccctc cagtatcacc     5640

atcaagtaaa actgagaaac actcacctgt gtcaccctct gcaaaaacgg aaagacattc     5700

acctgcgtca tcatcgagta aaactgagaa acactcacct gtatcaccct cgacaaaaac     5760

tgaaaggcac tctcctgtgt catctacaaa aacagaaaga cacccacctg tttcgccttc     5820

aggcaaaaca gacaaacgtc cacctgtatc gccctccggg aggacagaaa aacacccgcc     5880

agtatcgcct gggagaacag aaaaacgctt gcctgtttca ccctccggaa gaacggacaa     5940

gcaccaacct gtatcaacag ctgggaaaac tgagaagcac ctgcctgtgt caccttctgg     6000

caaaacagaa aagcaaccac ctgtatcccc cacttcaaaa acagagagga ttgaggaaac     6060

catgtctgtt cgggagctga tgaaggcttt ccagtcaggt caggaccctt ctaaacataa     6120

aactggactc tttgagcaca aatcagcaaa acaaaagcag ccacaagaga aaggtaaagt     6180

tcgggtagaa aaagaaaagg ggccgatact aacccagaga gaagctcaga aaacagagaa     6240

tcagacaatc aaacgaggcc agagactccc ggtaacgggc acagcagaat ccaaaagagg     6300

agttcgtgtt tcctccatag gagttaagaa agaagatgca gctggaggaa aggagaaagt     6360

tctcagccac aaaatacctg aacctgttca gtcagtgcct gaagaagaaa gccacagaga     6420

gagcgaagtg cccaaagaaa agatggctga tgagcaggga gacatggatc tacagatcag     6480

cccagatagg aaaacctcca ctgacttctc tgaggtcatt aagcaagagt tggaagacaa     6540

tgacaaatac caacaattcc gcctgagtga ggagacagaa aaggcacagc ttcacttaga     6600

ccaagtactc actagtcctt tcaacacaac atttccactc gactacatga aagatgagtt     6660

ccttccagct ctgtctttac aaagcggtgc tttagatggc agttctgaaa gcctaaagaa     6720

tgagggggta gccggctctc cgtgtggcag cctgatggag gggacccctc agattagttc     6780

agaagaaagc tataagcatg aaggcctagc agagacccct gagacgagcc cagaaagcct     6840

ttctttctca ccaaagaaaa gtgaggagca aactggggaa acaaaggaaa gcaccaagac     6900

agaaaccacc acagaaattc gttcagaaaa agagcatccc acgaccaaag acattactgg     6960

tggctctgaa gagcgaggtg ccacagtcac tgaggactca gagacctcta ctgagagttt     7020

tcagaaagag gccactctag gctctcccaa agacacaagc cctaaaagac aagatgattg     7080

cacaggcagc tgtagtgtag cattagctaa agagacacct acaggactga ctgaggaggc     7140

agcctgtgat gaaggtcaac gtacctttgg tagttcagcc cacaagacac aaactgatag     7200

tgaggttcaa gaatccacag ccacctcaga cgagacaaag gccttgccgc tgcctgaggc     7260

ttctgtaaag acagatacag gaactgaatc aaaacctcag ggagtcatta gaagtcccca     7320

agggttagaa cttgcactcc ctagccgaga tagcgaagtc ctcagcgctg tggctgatga     7380

ctcattagca gtgagccaca aagactctct ggaagccagc cctgtgctag aagataactc     7440

ttcacacaaa acccctgatt ctctggagcc aagtcctctg aaagaatccc cttgccgtga     7500

ctctctggaa agcagccctg ttgaaccaaa gatgaaggct ggaatttttc caagtcactt     7560

tcctcttcct gcagctgttg ccaaaacaga actcttgacg gaagtggcct ctgtgcggtc     7620

ccggctactc cgagaccctg atggcagtgc tgaggatgac agtcttgagc agacatcgct     7680

catggagagc tcagggaaga gccccctttc tcctgacacc cccagctctg aagaagtcag     7740

ctatgaggtt acacccaaaa ccacagatgt aagtacacca aaaccagctg tgattcatga     7800

atgtgcagag gaggatgatt cagaaaacgg ggagaaaaag aggttcacac ctgaagagga     7860

gatgtttaaa atggtaacca aaatcaaaat gtttgatgaa cttgaacaag aagcaaagca     7920

gaaaagggac tacaaaaaag aacccaaaca agaagaatct tcttcatctt ctgacccaga     7980

tgctgactgt tcagtagatg tggatgaacc aaaacataca ggcagtgggg aggatgaaag     8040

tggtgtccct gtgttagtaa cttcggagag caggaaggtg tcttcctcct cagaaagtga     8100

acctgagttg gcacagctta aaaaaggtgc tgactcaggc cttttaccag aaccagtgat     8160

tcgagtacaa cctccttctc cacttccatc aagcatggac tccaattcca gtccagaaga     8220

agtacaattc cagcctgtcg tttccaaaca atatactttc aagatgaatg aagatactca     8280

ggaagagcca ggcaaatcag aagaagaaaa agattctgaa tcccatttag ctgaagaccg     8340

tcatgctgtt tccactgagg ctgaagacag gtcttatgat aagctaaaca gagacactga     8400

tcagccaaaa atctgtgatg gccatggatg tgaggccatg agtcctagca gctcagctgc     8460

tcctgtctct tcaggtctac agagtccgac tggtgatgat gttgatgaac agccagtcat     8520

ctataaagaa tcattagctc tccaaggcac tcatgaaaaa gacacagagg gagaagagct     8580

tgatgtttct agagcagaat ctccacaagc agattgcccc agtgaaagct tttcatcttc     8640

atcctctttg cctcattgtt tggtatctga aggaaaagaa ttagatgaag acatatctgc     8700

cacatcttct attcaaaaaa cagaggtcac aaaaactgat gaaacatttg agaacttacc     8760

aaaggactgc ccctctcaag actcatccat tactactcaa acagatagat tttccatgga     8820

tgttcccgtg tctgacctag ctgagaatga tgaaatctat gatccacaaa tcactagccc     8880

ttatgaaaat gtcccttccc aatctttttt ctctagtgaa gaaagcaaaa cccaaacaga     8940

tgcaaatcac accacaagtt ttcactcttc tgaagtgtat tctgttacca tcacatcccc     9000

tgttgaagac gttgtagtgg caagctcctc tagtggaact gttttaagca aagaatctaa     9060

ttttgagggc caggacataa aaatggaatc ccaacaggaa agtaccttgt gggaaatgca     9120

atcagacagt gtctcttcat ctttcgagcc tactatgtcc gctacaacaa cagttgttgg     9180

tgaacaaata agcaaagtca tcatcacaaa aactgatgtg gattctgatt cttggagtga     9240

aattcgggaa gacgatgaag cctttgaggc tcgtgtgaaa gaggaagaac aaaagatatt     9300

tggtttgatg gtagacagac aatcacaggg taccacccct gacaccactc ctgctaggac     9360

cccaactgaa gaggggaccc caacaagtga gcaaaaccca tttctgtttc aggaaggaaa     9420

attgtttgaa atgacccgaa gtggtgccat tgatatgacc aaaaggtcct atgcagatga     9480

aagttttcac tttttccaaa ttggtcaaga atccagggaa gagactctct ctgaagatgt     9540

gaaagaaggg gctactgggg ctgatcccct accgctggag acatcagctg aatcactagc     9600

actttcagaa tcaaaagaaa cagtggatga tgaggcagac ttacttccag atgacgtgag     9660

tgaggaagta gaggaaatac ctgcttcgga tgctcaactt aactcccaaa tggggatttc     9720

agcctccact gaaacaccta caaaagaagc tgttagtgta gggaccaagg acctccccac     9780

cgtgcaaacg ggtgatatac ctcctctctc tggtgtaaag cagatatcct gccccgactc     9840

ttctgaacca gctgtacaag tccagttaga tttttccaca ctcaccaggt ctgtttattc     9900

agataggggt gatgattctc ccgattcttc cccagaagaa cagaaatcag taatcgagat     9960

tcctactgca cccatggaga atgtgccttt tactgaaagc aaatccaaaa ttcctgtaag    10020

gactatgccc acttccaccc cagcacctcc atctgcagag tatgagagtt cagtttctga    10080

agattttcta tccagtgtag atgaggaaaa taaggcggat gaagcaaaac caaagtccaa    10140

actccctgtc aaagtacccc tccaaagagt tgaacagcag ctctcagatc tagacacctc    10200

tgtccagaag acagtggctc ctcagggaca ggacatggca agcatcgcac cagataatag    10260

aagcaaatct gaatctgatg ctagttcttt ggattcaaag accaaatgcc cagtaaaaac    10320

ccgaagttac actgagacag aaacagagag cagagagagg gccgaggaac ttgagttaga    10380

atcagaagaa ggggccacaa gaccaaagat acttacatcc cgattgccag ttaagagcag    10440

aagcactaca tcttcctgca gggggggcac gagccccaca aaagaaagta aggagcattt    10500

ctttgacctt tacagaaatt ccatagaatt ctttgaggag attagtgatg aggcttccaa    10560

attagtggat aggctgacac agtcagagag ggagcaggaa atagtttcag acgatgaaag    10620

tagtagtgcc ctggaagtat cagtaattga aaatctgcca cctgttgaga ccgagcactc    10680

agttcctgag gacatctttg acacaaggcc catttgggat gagtctattg agactctgat    10740

tgaacgcatc cctgatgaaa atggccatga ccatgctgaa gatccacagg atgagcagga    10800

acggatcgag gaaaggctgg cttatattgc tgatcacctt ggcttcagct ggacagaatt    10860

agcaagagaa ctggatttca ctgaggagca aattcatcaa attcgaattg aaaatcccaa    10920

ctctcttcaa gaccagagtc atgcactgtt gaagtactgg ctagagaggg atgggaaaca    10980

tgctacagat accaacctcg ttgaatgtct caccaagatc aaccgaatgg atattgttca    11040

tctcatggag accaacacag aacctctcca ggagcgcatc agtcatagtt atgcagaaat    11100

tgaacagacc attacactgg atcatagtga agggttctcg gtacttcaag aggagttatg    11160

cactgcacag cacaagcaga aagaggagca agctgtttct aaagaaagtg agacctgcga    11220

tcaccctcct atcgtctcag aggaagacat ttctgttggt tattccactt ttcaggatgg    11280

cgtccccaaa actgaggggg acagctcagc aacagcactc tttccccaaa ctcacaagga    11340

gcaagttcaa caggatttct cagggaaaat gcaagacctg cctgaagagt catctctgga    11400

atatcagcag gaatattttg tgacaactcc aggaacagaa acatcagaga ctcagaaggc    11460

tatgatagta cccagctctc ccagcaagac acctgaggaa gttagcaccc ctgcagagga    11520

ggagaagctg tacctccaga ccccaacatc cagcgagcgg ggaggctctc ccatcataca    11580

agaacccgaa gagccctcag agcacagaga ggagagctct ccgcggaaaa ccagcctcgt    11640

aatagtggag tctgccgata accagcctga gacctgtgaa agactcgatg aagatgcagc    11700

ttttgaaaag ggagacgata tgcctgaaat acccccagaa acagtcacag aagaagaata    11760

cattgatgag catggacaca ccgtggtaaa gaaggttact aggaaaatca ttaggcggta    11820

tgtatcctct gaaggcacag agaaagaaga gattatggtg cagggaatgc cacaggaacc    11880

tgtcaacatc gaggaagggg atggctattc caaagttata aagcgtgttg tattgaagag    11940

tgacaccgag cagtcagagg acaacaatga gtaaagccat cacacagaag agggctgtgg    12000

tgaaggacca gcatggaaaa cgcattgact tggagcacct ggaggatgta ccagaagcac    12060

tagaccagga cgacctccag cgcgatctcc agcagctcct tcggcatttc tgcaaggagg    12120

acttgaagca agaggccaag tgaggggctg cccagttctc acaccagaaa ccacacattc    12180

actcaatatg cagcttcctg tttcagtagg ggagtgacct aactggccta attaatggga    12240

taccccgaca tttccactgt tagcaaatat acggcatttt gctttagttt tcccccatcc    12300

tctttaacta taaagctaat ttgtgaccaa agatggcatc cttcatactg gatgctgtat    12360

ccaatacttt gttgtgtctg tgctaacctg ggaactggcc acctccattg ttctttgctt    12420

ctgcacaaga tccatgaaaa tccattgatc agaagaactt cacctgcaga cctcttcaag    12480

tgacactatg taggaatcct tccaaggaat atctatgtac aatgtatata gctgaaatgc    12540

tcagatgaac aacatattaa aattaaaacc actgcctatt gtaactacac tgggcatcag    12600

aataaaaggc ctctagaaat tgctgaacaa tggttaatta agatattgct aacacaatcg    12660

agtgataata cagttttact gcaaaagaag cacttcaaac ctattatgtc cttagaactt    12720

ccagagtagc cactgctccc agttaaaggt gggtcagtag ccttgcagaa ctgtcctgag    12780

aagttattgc tggtgctggc cagccatggc ttaggactcc aacagccact ctgagggagg    12840

ggagaaggga gcagaggcca cgcagaatga accgatgggg tattcagttg ctggcagcta    12900

cattgtgtgg cattctagca tcttcaggtc tttagatctt ggacaagttg gcagggtatt    12960

ttaaaagcta taactactgt agttttccag ttttcattgc tgctttagca aaccacgctg    13020

tcttacagtg gtactttctt ctggccactg cactgtagat aattcattgg aaacaagatt    13080

tacccactac ataaaaggtt aaactccttc agtatgttgg agtggtttct tttttttttt    13140

ctttctttct tttttttctt caggtttata tcttctctaa tacctgcatg tggcgtttaa    13200

aaatcaagac cacggtcaaa cccctcttct aatcacatta attgtttcca ttctttttac    13260

cctgagtgag cacttttcac tttccagcta ggtctgtttt tcagcttgca gacaagattg    13320

agaaatcctt gaaaatttgg ttttggttaa aatttttggt ttatttattt gaaatccaca    13380

ctcccttgga aactcttaag tgcatttgtg cacttctgtt tgtttgtctc aaagaaggga    13440

ctgtaacaat ctgagtaatt tccatgtcct cttccttatt cctctagtgg ttgaagctgt    13500

gtagcatttt aacatatata tattcacaaa tatattcata taaacagtat acattttgaa    13560

tcagtcattt gttaaagaaa agtatattca atgaagatga aatttaaata aaaaaggaca    13620

gagtctatcc tccagggatt gaacattttc caattatctg gtcttttcct gttgtgcaaa    13680

aatgactcat tgctccgaat gtcaaaaaca aatgcgacaa acaatggcac ttcatcattt    13740

aaagtaatgt tgccaagaga aaaaatttcc tgggagggag gtttcccaca agccaaatct    13800

cctaagcctc aaatgctagc actttttggc agttggatag gaaatgagac attctttggc    13860

agccaaaata agagaggccg atggtgaaac tttttgagac accctatggc cttcttgtca    13920

aaaccttcac tggagctcaa gaaaagcatt tctgttgtgt tatttgcagt gcagatgatg    13980

tctgtgtaac aacataatgg ttattcacct ttttttgatt ttgatttttg ctgtgttatc    14040

aaaaacttga atactgtgag aagaagtgaa ttttcagttg acgaatcagc atcttgttcc    14100

catggtgata acactaattg aatatatcta tgagggcatg tattagttaa tggaaaaaaa    14160

aatacaacac taacaataca tagctgcaat gtgtacaatg gctgatttaa ttaaataaaa    14220

tgtacaagtg ttaaatgtgg caa                                            14243


<210>  121
<211>  7988
<212>  DNA
<213>  homo sapiens

<400>  121
ctcctcctcc tgctttcctc cagtaagtgc atacccgcta gtggtctgta caggcggcac       60

ggtttgatgg cagagatatt ttctttccaa actgttcaaa atgatgaacg aagatgcagc      120

tcagaaaagc gacagtggag agaagttcaa cggcagtagt cagaggagaa aaagacccaa      180

gaagtctgac agcaatgcaa gcttcctccg tgctgccaga gcaggcaacc tggacaaagt      240

tgtggaatat ctgaaggggg gcatagacat caatacctgc aatcagaatg gactcaacgc      300

tctccatctg gctgccaagg aaggccacgt ggggctggtg caggagctgc tgggaagagg      360

gtcctctgtg gattctgcca ctaagaaggg aaataccgct cttcacattg catctttggc      420

tggacaagca gaagttgtca aagttcttgt taaggaagga gccaatatta atgcacagtc      480

tcagaatggc tttactcctt tatacatggc tgcccaagag aatcacattg atgttgtaaa      540

atatttgctg gaaaatggag ctaatcagag cactgctaca gaggatggct ttactcctct      600

agctgtggca ctccagcaag gacacaacca ggcggtggcc atcctcttgg agaatgacac      660

caaagggaaa gtgaggctgc cagctctgca tattgccgct aggaaagacg acaccaaatc      720

tgccgcactt ctgcttcaga atgaccacaa tgctgacgta caatccaaga tgatggtgaa      780

taggacaact gagagtggtt ttaccccttt gcacatagct gcacattacg gaaatgtcaa      840

cgtggcaact cttcttctaa accggggagc tgctgtggac ttcacagcca ggaatggaat      900

cactcctctg catgtggctt ccaaaagagg aaatacaaac atggtgaagc tcttactgga      960

tcgaggcggt cagatcgatg ccaaaactag ggatgggttg acaccacttc actgtgctgc     1020

acgaagtggg catgaccaag tggtggaact tctgttggaa cggggtgccc ccttgctggc     1080

aaggactaag aatgggctgt ctccactaca catggctgcc cagggagacc acgtggaatg     1140

tgtgaagcac ctgttacagc acaaggcacc tgttgatgat gtcaccctag actacctgac     1200

agccctccac gttgctgcgc actgtggcca ctaccgtgta accaaactcc ttttagacaa     1260

gagagccaat ccgaacgcca gagccctgaa tggttttact ccactgcaca ttgcctgcaa     1320

gaaaaaccgc atcaaagtca tggaactgct ggtgaaatat ggggcttcaa tccaagctat     1380

aacagagtct ggcctcacac caatacatgt ggctgccttc atgggccact tgaacattgt     1440

cctccttctg ctgcagaacg gagcctctcc agatgtcact aacattcgtg gtgagacggc     1500

actacacatg gcagcccgag ccgggcaggt ggaagtggtc cgatgcctcc tgagaaatgg     1560

tgcccttgtt gatgccagag ccagggagga acagacacct ttacatattg cctcccgcct     1620

gggtaagaca gaaattgtcc agctgcttct acaacatatg gctcatccag atgcggccac     1680

tacaaatggg tacacaccac tgcacatctc tgcccgggag ggccaggtgg atgtggcatc     1740

agtcctattg gaagcaggag cagcccactc cttagctacc aagaagggtt ttactcccct     1800

gcatgtagca gccaagtatg gaagcctgga tgtggcaaaa cttctcttgc aacgccgtgc     1860

tgccgcagat tctgcaggga agaacggcct taccccgctc catgttgctg ctcattatga     1920

caaccagaag gtggcgctgc tgttactgga gaagggtgct tcccctcatg ccactgccaa     1980

gaatggctat actccgttac atattgctgc caagaagaat caaatgcaga tagcttccac     2040

actcctgaac tatggagcag agacaaacat tgtgacaaag caaggagtaa ctccactcca     2100

tctggcctcg caggaggggc acacagatat ggttaccttg cttctggata agggagccaa     2160

tatccacatg tcaactaaga gtggactcac atccttacac cttgcagccc aggaagataa     2220

agtgaatgtt gctgatattc tcaccaagca tggagctgat caggatgctc atacaaagct     2280

tggttacaca cctttaattg tggcctgtca ctatggaaat gtgaaaatgg tcaactttct     2340

tctgaagcag ggagcaaatg ttaacgcaaa aaccaagaac ggctacacgc ctttgcacca     2400

ggccgctcag cagggtcaca cgcacatcat caacgtcctg ctccagcatg gggccaagcc     2460

caacgccacc actgcgaatg gcaacactgc cttggcgatt gctaagcgtc tgggctacat     2520

ctccgtggtc gacaccctga aggttgtgac tgaggaggtc accaccacca ccacaactat     2580

tacagaaaaa cacaaactaa atgtacctga gacgatgact gaggttcttg atgtttctga     2640

tgaagagggt gatgacacaa tgactggtga tgggggagaa taccttaggc ctgaggacct     2700

aaaagaactg ggtgatgact cactacccag cagtcagttc ctggatggta tgaattacct     2760

gcgatacagc ttggagggag gacgatctga cagccttcga tccttcagtt ccgacaggtc     2820

tcacactctg agccatgcct cctacctgag ggacagtgcc gtgatggatg actcagttgt     2880

gattcccagt caccaggtgt caactctagc caaggaggca gaaaggaatt cttatcgcct     2940

aagctggggc actgagaact tagacaacgt ggctctttct tctagtccta ttcattcagg     3000

tttcctggtt agttttatgg tggatgcccg aggtggtgct atgcgaggat gcagacacaa     3060

tgggctccga atcattattc cacctcggaa atgtactgct ccaacgcgag tcacctgccg     3120

actggtcaag cgccacagac tggcaacaat gcctccaatg gtggaaggag aaggcctggc     3180

cagtcgcctg atcgaagttg gaccttctgg tgctcagttc cttggtaaac ttcacctgcc     3240

aacggctcct cccccactta atgagggaga aagtttggtc agccgcattc ttcagctggg     3300

gcctcctgga accaaattcc ttgggcctgt gatcgtggag atccctcact ttgcggccct     3360

tcgaggaaag gaaagggaac tggtggtcct gcgcagtgag aatggggaca gctggaaaga     3420

gcatttctgt gactacactg aagatgaatt gaatgaaatt cttaacggca tggatgaagt     3480

actggatagc ccagaagacc tagaaaagaa acgaatctgc cgcatcatca cccgagactt     3540

cccacagtac tttgcagtgg tgtctcgtat caaacaggac agcaatctga ttggcccaga     3600

aggaggtgta ctgagcagca cagtggtgcc ccaggtgcag gccgtcttcc cagagggggc     3660

actcaccaag cggatccgcg taggcctgca ggctcaacct atgcacagtg agctggttaa     3720

gaagatccta ggcaacaaag ctaccttcag ccctatagtc actttggaac ctagaagaag     3780

aaaattccac aaaccaatta ccatgaccat tcctgtcccc aaagcttcaa gtgatgtcat     3840

gttgaatggt tttgggggag atgcaccaac cttaagatta ctatgcagca taacaggtgg     3900

aaccacccct gcccagtggg aagatattac aggaactacg ccattaacat ttgtcaatga     3960

atgtgtttcc tttacaacaa acgtgtctgc caggttctgg ctgatagatt gtcgacagat     4020

ccaggaatcc gttacttttg catcacaagt atacagagaa attatctgcg taccttatat     4080

ggccaaattt gtagtgtttg ccaaatcaca tgaccccatt gaagccaggt tgaggtgttt     4140

ctgcatgact gatgataaag tggataagac ccttgaacaa caagaaaatt ttgctgaggt     4200

ggccagaagc agggatgtgg aggtgttaga aggaaaaccc atctacgttg attgtttcgg     4260

caacttggta ccattaacta aaagtggcca gcatcatata ttcagttttt ttgccttcaa     4320

agaaaataga cttcctctat ttgtcaaggt acgcgatacg actcaggaac cttgcggacg     4380

actatcattt atgaaggagc caaaatccac gagaggcctg gtgcatcaag ctatttgcaa     4440

cttaaacatc actttgccga tttatacaaa ggaatcagag tcagatcaag aacaggagga     4500

agagatcgat atgacatcag aaaaaaatcc acaggatgag caggaacgga tcgaggaaag     4560

gctggcttat attgctgatc accttggctt cagctggaca gaattagcaa gagaactgga     4620

tttcactgag gagcaaattc atcaaattcg aattgaaaat cccaactctc ttcaagacca     4680

gagtcatgca ctgttgaagt actggctaga gagggatggg aaacatgcta cagataccaa     4740

cctcgttgaa tgtctcacca agatcaaccg aatggatatt gttcatctca tggagaccaa     4800

cacagaacct ctccaggagc gcatcagtca tagttatgca gaaattgaac agaccattac     4860

actggatcat agtgaagggt tctcggtact tcaagaggag ttatgcactg cacagcacaa     4920

gcagaaagag gagcaagctg tttctaaaga aagtgagacc tgcgatcacc ctcctatcgt     4980

ctcagaggaa gacatttctg ttggttattc cacttttcag gatggcgtcc ccaaaactga     5040

gggggacagc tcagcaacag cactctttcc ccaaactcac aaggagcaag ttcaacagga     5100

tttctcaggg aaaatgcaag acctgcctga agagtcatct ctggaatatc agcaggaata     5160

ttttgtgaca actccaggaa cagaaacatc agagactcag aaggctatga tagtacccag     5220

ctctcccagc aagacacctg aggaagttag cacccctgca gaggaggaga agctgtacct     5280

ccagacccca acatccagcg agcggggagg ctctcccatc atacaagaac ccgaagagcc     5340

ctcagagcac agagaggaga gctctccgcg gaaaaccagc ctcgtaatag tggagtctgc     5400

cgataaccag cctgagacct gtgaaagact cgatgaagat gcagcttttg aaaagggaga     5460

cgatatgcct gaaatacccc cagaaacagt cacagaagaa gaatacattg atgagcatgg     5520

acacaccgtg gtaaagaagg ttactaggaa aatcattagg cggtatgtat cctctgaagg     5580

cacagagaaa gaagagatta tggtgcaggg aatgccacag gaacctgtca acatcgagga     5640

aggggatggc tattccaaag ttataaagcg tgttgtattg aagagtgaca ccgagcagtc     5700

agaggacaac aatgagtaaa gccatcacac agaagagggc tgtggtgaag gaccagcatg     5760

gaaaacgcat tgacttggag cacctggagg atgtaccaga agcactagac caggacgacc     5820

tccagcgcga tctccagcag ctccttcggc atttctgcaa ggaggacttg aagcaagagg     5880

ccaagtgagg ggctgcccag ttctcacacc agaaaccaca cattcactca atatgcagct     5940

tcctgtttca gtaggggagt gacctaactg gcctaattaa tgggataccc cgacatttcc     6000

actgttagca aatatacggc attttgcttt agttttcccc catcctcttt aactataaag     6060

ctaatttgtg accaaagatg gcatccttca tactggatgc tgtatccaat actttgttgt     6120

gtctgtgcta acctgggaac tggccacctc cattgttctt tgcttctgca caagatccat     6180

gaaaatccat tgatcagaag aacttcacct gcagacctct tcaagtgaca ctatgtagga     6240

atccttccaa ggaatatcta tgtacaatgt atatagctga aatgctcaga tgaacaacat     6300

attaaaatta aaaccactgc ctattgtaac tacactgggc atcagaataa aaggcctcta     6360

gaaattgctg aacaatggtt aattaagata ttgctaacac aatcgagtga taatacagtt     6420

ttactgcaaa agaagcactt caaacctatt atgtccttag aacttccaga gtagccactg     6480

ctcccagtta aaggtgggtc agtagccttg cagaactgtc ctgagaagtt attgctggtg     6540

ctggccagcc atggcttagg actccaacag ccactctgag ggaggggaga agggagcaga     6600

ggccacgcag aatgaaccga tggggtattc agttgctggc agctacattg tgtggcattc     6660

tagcatcttc aggtctttag atcttggaca agttggcagg gtattttaaa agctataact     6720

actgtagttt tccagttttc attgctgctt tagcaaacca cgctgtctta cagtggtact     6780

ttcttctggc cactgcactg tagataattc attggaaaca agatttaccc actacataaa     6840

aggttaaact ccttcagtat gttggagtgg tttctttttt tttttctttc tttctttttt     6900

ttcttcaggt ttatatcttc tctaatacct gcatgtggcg tttaaaaatc aagaccacgg     6960

tcaaacccct cttctaatca cattaattgt ttccattctt tttaccctga gtgagcactt     7020

ttcactttcc agctaggtct gtttttcagc ttgcagacaa gattgagaaa tccttgaaaa     7080

tttggttttg gttaaaattt ttggtttatt tatttgaaat ccacactccc ttggaaactc     7140

ttaagtgcat ttgtgcactt ctgtttgttt gtctcaaaga agggactgta acaatctgag     7200

taatttccat gtcctcttcc ttattcctct agtggttgaa gctgtgtagc attttaacat     7260

atatatattc acaaatatat tcatataaac agtatacatt ttgaatcagt catttgttaa     7320

agaaaagtat attcaatgaa gatgaaattt aaataaaaaa ggacagagtc tatcctccag     7380

ggattgaaca ttttccaatt atctggtctt ttcctgttgt gcaaaaatga ctcattgctc     7440

cgaatgtcaa aaacaaatgc gacaaacaat ggcacttcat catttaaagt aatgttgcca     7500

agagaaaaaa tttcctggga gggaggtttc ccacaagcca aatctcctaa gcctcaaatg     7560

ctagcacttt ttggcagttg gataggaaat gagacattct ttggcagcca aaataagaga     7620

ggccgatggt gaaacttttt gagacaccct atggccttct tgtcaaaacc ttcactggag     7680

ctcaagaaaa gcatttctgt tgtgttattt gcagtgcaga tgatgtctgt gtaacaacat     7740

aatggttatt cacctttttt tgattttgat ttttgctgtg ttatcaaaaa cttgaatact     7800

gtgagaagaa gtgaattttc agttgacgaa tcagcatctt gttcccatgg tgataacact     7860

aattgaatat atctatgagg gcatgtatta gttaatggaa aaaaaaatac aacactaaca     7920

atacatagct gcaatgtgta caatggctga tttaattaaa taaaatgtac aagtgttaaa     7980

tgtggcaa                                                              7988


<210>  122
<211>  4846
<212>  DNA
<213>  homo sapiens

<400>  122
gagcggtgct caggggaggg ctggagggga gggaaggaga gagagagggg agggcggcac       60

cgcccctagc cccgcgctcc ggaagtgaag cggccagacc accagctaat ggatgcggag      120

cggagggccc gctgaccgct ctccgcgcct ggagcagctt ggcttggctg gagctaagag      180

ccagacacac cactgtgtgg aggtgggtga tgtcttcctg tgctaaaagg tgaataaata      240

agctcctcac ctctcgcgga acactcggga acacatcaac aggggtccaa gccgccctgc      300

tgggaggctt ctcttcaaga gttctgggtc ccagagtgga aggcattttc ccatcaactg      360

gagagagacg aaacatcaga gaccaggagg ctgtggagaa agcagctgtc ccaggtgcct      420

caactatcag agaagggtca gcgtcacgtg gctgccagca tctttgagaa aatcactggc      480

aatcggactt cagagctgcg ggcacaggtg tggttagaac tgagatacga cctgcccacc      540

tgggtcaggc ctaaagacaa gaagtcctga gttcttgcca ctgagtaggc cagggtcatt      600

tgtccagaaa actttgtgac tgtctttgag tgacctagtc tgggacccat tcattggtgg      660

gttctaaggt tagaagctca tccaggatat tttcaatatt aagtcagtgc atagctgcac      720

cactaacaaa ttggtgcctg tagagtcaga gtgggtcaat tcttaggaca atggcgctgg      780

cactgttaga ggactggtgc aggataatga gtgtggatga gcagaagtca ctgatggtta      840

cggggatacc ggcggacttt gaggaggctg agattcagga ggtccttcag gagactttaa      900

agtctctggg caggtataga ctgcttggca agatattccg gaagcaggag aatgccaatg      960

ctgtcttact agagcttctg gaagatactg atgtctcggc cattcccagt gaggtccagg     1020

gaaagggggg tgtctggaag gtgatcttta agacccctaa tcaggacact gagtttcttg     1080

aaagattgaa cctgtttcta gaaaaagagg ggcagacggt ctcgggtatg tttcgagccc     1140

tggggcagga gggcgtgtct ccagccacag tgccctgcat ctcaccagaa ttactggccc     1200

atttgttggg acaggcaatg gcacatgcgc ctcagcccct gctacccatg agataccgga     1260

aactgcgagt attctcaggg agtgctgtcc cagccccaga ggaagagtcc tttgaggtct     1320

ggttggaaca ggccacggag atagtcaaag agtggccagt aacagaggca gaaaagaaaa     1380

ggtggctggc ggaaagcctg cggggccctg ccctggacct catgcacata gtgcaggcag     1440

acaacccgtc catcagtgta gaagagtgtt tggaggcctt taagcaagtg tttgggagcc     1500

tagagagccg caggacagcc caggtgaggt atctgaagac ctatcaggag gaaggagaga     1560

aggtctcagc ctatgtgtta cggctagaaa ccctgctccg gagagcggtg gagaaacgcg     1620

ccatccctcg gcgtattgcg gaccaggtcc gcctggagca ggtcatggct ggggccactc     1680

ttaaccagat gctgtggtgc cggcttaggg agctgaagga tcagggcccg ccccccagct     1740

tccttgagct aatgaaggta atacgggaag aagaggagga agaggcctcc tttgagaatg     1800

agagtatcga agagccagag gaacgagatg gctatggccg ctggaatcat gagggagacg     1860

actgaaaacc acctgggggc aggacccaca gccagtgggc taagaccttt aaaaaatttt     1920

tttctttaat gtatgggact gaaatcaaac catgaaagcc aattattgac cttccttcct     1980

tccttccttc cctcccttcc tccttctctc cttctctcct cctctctcct ctcctctcct     2040

ctctttcctt ccttccttcc ttttttcttt ttctctttct tctttatttc ttgggtctca     2100

ctctcatcac ccaggctaga gtgcagtggc acaaaaatct cggctcactg cagccttgac     2160

ttcccaggct caggctcagg tgatcctcac accttagcct cccaagtacc tgggactaca     2220

ggcacgcacc accatgccta gctattcttt tgtatttttg gtagagacag ggttttgctg     2280

tgttgctcag gctggtctgg aacccctagg ctcaaatgat gtgcccaact cggcctccca     2340

aagtgctggg attacaggca tgaaccgcca tgcctggccc ttgatttttc tttttaagaa     2400

aaaaatatct aggagtttct tagaccctat gtagattatt aatgaacaaa agattaaact     2460

ccaaatatta aatagtaagc ctgaaggaat ctgaaacact tgtacttcca attttcttta     2520

aataatccca aatagaccag aattggccca taccatagaa gaaagaattg gcagtcaaaa     2580

aaaaaaatac cttttgtaat gtttgaaaaa taaagctgtt tgacttgtca ggtgttttcc     2640

tttctcaaat cagcaaattc tctctgagtg cctggctttg tgagacactg tacaaggagt     2700

tacaagacta cagctataac ctgcagttga gcagttataa acctacaaaa tgggccctgc     2760

cctcagagag gttccagtct agatgaggag ctgatctaga caggtaaaag gctaactaac     2820

cctttgtgta aataagttca tcaccccagt aaaagtgtca tcacccagtg aataggacca     2880

cctctgcctg cagatttttg ttgttgttgt tgtcattgtt gttgttgttt taacctggga     2940

agtgttcttc ctgcctttct gctaggtgtc agatagatgg tcccagagct aggtgctgtg     3000

tcaggccctg aagacacaga tgactcaacc taagctttac tttccagagg tccacagcct     3060

gagaggtgtc cccaaagaaa gggggacatg aggggactgc atgcttgaga gcagggttgt     3120

ttagggcagg tttggattta gtgagcaggc tggtttgctt agagaaggct tttagtggca     3180

acaaaggatg aagaggagag aaaaggaact cacatttatt gagggcctac tgtgtgcaaa     3240

gtgtttcatg tatatctcat tgaatgtata cagccaccct gttgtggtat aattttgctc     3300

tttataaaga gaaagaccga agctcagatg agttaagtgg tctcctcaac accaaaatgc     3360

caagaagtga tggagcctag acagaagccc agaactttct gactcacact agtccatcct     3420

ctaccatcac gatgactttc aaattgtgct ctgcagttct gcagattttc tagcagtgcc     3480

atctccaaaa tgtgttttaa actctttatt tttttaatta ttattagtat tattttgaga     3540

ctgagtcttg ctctatcacc caggctggag tgcagtggtg caatctcagc tcactgcaac     3600

ctccgcctcc caggttcaag cgatttcgtg cctcagcctc ccgagtagct gggattacag     3660

gcacccacca ccacgcccag ctaatttttg tatttttagt agaaatgggg tttcaccatg     3720

ttggccaggc tggtctcgaa ctcctgacct caagtgatcc actcacctcg gcctcccaaa     3780

gtgctgggat tacaggtgtg agccaccatg cctgggctaa actctttaag tctctagtaa     3840

atgcagctag attcaaatgg gctgataacc aaattttaac acatcagcat tcaccaccag     3900

gtttactttt attttcagat tggctcattt tgtgcagacc ttagagcaaa gtttccttta     3960

tggtatctgt gtacgtatcc aaacttcttt taattgttca cagattttaa aagcggtagc     4020

accacatggt tgtgtagatc agacctgtgt atttagatca gacctgtgta tcacgtaagt     4080

gtgtgagtgc agtgcagatg agcaccattt agttatatgt gctaggcaaa tctccaacac     4140

agttgatgtg tagtcttgtg gtagatttgt gcatactgta agcaaattgc ttagcttctc     4200

tagacatcag tttccacatc tgaaaaataa gaagatgaga gtacacggtt gttatgaaca     4260

aatgacttaa tgctttttaa gcacgttgca tgacatctgg aacacagaaa gccctcaata     4320

cattgaagct cttaggattt tcacgatgtt cctgtctgct caatgcatgc tttctttatt     4380

gttctgacag ttgtgtggta acaagctaat atgcttccag ttgacttcca gtctaccctg     4440

gtgttagaaa ccgtttcatc tcttattgta aatttgagtg cttgttgttt tttatatttg     4500

tgatgactct tccagcagtt gttgacaatt gttagaggtt tgacttttaa ataattactt     4560

attttttctg attgtggttc agtttaactg aagaatatcc tgagattgta agaaaagcat     4620

tttttaaaag gtatcacttg tgatcattta tctttctaaa ttctattttt aatactgttc     4680

caccaaagtg atgcagtggt taccatgaca ccctaatttc atgtgttttt gtatttatga     4740

aaatagtttc attgtcattt attggcggta tacaaagtaa aatgttataa atgtgaagtt     4800

ataaaataaa tatatgctaa taaaatcctg agtttttctg tttcct                    4846


<210>  123
<211>  4869
<212>  DNA
<213>  homo sapiens

<400>  123
gtcatgctct attgcgcata tctcggggcg ggggaggaac ggagattgac aaggaggcag       60

aggcctgagc gaggcggaaa atcctcaccc cggcccgcgg gtagacccaa acttctagcg      120

cgtcacttcc gctgggggcg gagcggggcg gggctgagtg ggtggcgacc tagctgctgc      180

gccagtgttt gtgttggaag ctcagctgat gcaggccggt tggagtggac gtcattgccg      240

ggaacgagcg agtcgccgct gcagccctag tgactgcggc ctgcatcccg attgtcttct      300

cctccaaggt ctacatgatt acctgaagtt taataatttt gcctttctag agtgttatac      360

agctggaatc atactgctat ggtccgaatg tttgtgcctc tcaaaattca tgtggaaatc      420

ataaccgcta aagtgatggt attaagaggt aagaccatga attatggcat ttcttaaatg      480

aagcgttcaa gaagtgagag aatgtcatag aaaataaatg atttttaagt tatgtctatt      540

aatctgactg tagatatata tatttacctc cttagtaatg caagaagtgt ttgtgggaag      600

cagagaagca agcaactgta tttcttgttc tcacctaagc attactggag gataagccac      660

atcagtctac aaagaggttt tcatacaaac ataataagat gtaaatggac caaaagtgaa      720

gcacattctt gcagtaagca ctgttactct ccaagcaacc atggtttaca tattgggatt      780

ttgaaactta gcacttctgc tcccaaggga cttacaaaag tgaacatttg tatgtcccgt      840

attaaaagta ctttgaactc tgtttcaaag gctgtttttg gcaatcaaaa tgaaatgatt      900

tcacgtttag ctcaatttaa gccaagttcc caaattttaa gaaaagtatc ggatagtggc      960

tggttaaaac agaaaaacat caaacaagcc atcaaatctc tgaaaaaata tagtgacaaa     1020

tcagcagaaa agagtccttt tccagaagag aaaagtcaca ttatagacaa agaagaagat     1080

ataggtaaac gcagtctttt tcattacaca agttctataa ccacaaaatt tggagactca     1140

ttctactttt tatcaaatca tattaattca tatttcaaac gtaaggaaaa aatgtctcaa     1200

caaaaggaaa atgaacattt ccgggacaaa tcagaacttg aagataaaaa ggtagaagag     1260

gggaaattaa gatctccaga tcctggcatc ctggcttata agccaggctc agaatctgta     1320

catacggtgg acaagcctac aagtccttct gcgatacctg atgttcttca agtttcaact     1380

aaacaaagta ttgctaactt tctttctcgt cccacggaag gtgtacaagc tttagtaggt     1440

ggttatattg gtggacttgt ccccaaatta aagtatgatt caaagagtca gtcagaagaa     1500

caggaagagc ctgctaaaac tgatcaggct gtcagcaaag acagaaatgc agaggagaaa     1560

aagcgtttat ctcttcagcg agaaaagatt atcgcaaggg tgagtattga taacaggacc     1620

cgggcattag ttcaggcatt aagaagaaca actgacccaa agctctgcat tactagggtt     1680

gaagaactga cttttcatct tctagaattt cctgaaggaa aaggagtggc tgtcaaggaa     1740

agaattattc catatttatt acgactgaga caaattaagg atgaaactct tcaggctgca     1800

gttagagaaa ttttggccct aattggctat gtggatccag tgaaagggag aggaatccga     1860

attctctcaa ttgatggtgg aggaacaagg ggcgtggttg ctctccagac cctacgaaaa     1920

ttagttgaac ttactcagaa gccagttcat cagctctttg attacatttg tggtgtaagc     1980

acaggtgcca tattagcttt catgttgggg ttgtttcata tgcccttgga tgaatgtgag     2040

gaactttatc gaaaattagg atcagatgta ttttcacaaa atgtcattgt tggaacagta     2100

aaaatgagtt ggagccatgc attttatgac agtcaaacat gggaaaacat tcttaaggat     2160

aggatgggat ctgcactgat gattgaaaca gcaagaaacc ccacatgtcc taaggtagct     2220

gctgtaagta ccatagtaaa tagagggata acacccaaag cttttgtgtt cagaaactat     2280

ggtcattttc ctggaatcaa ctctcattat ttgggaggct gtcagtataa aatgtggcag     2340

gccattagag cctcatctgc tgctccaggc tactttgcag aatatgcatt gggaaatgat     2400

cttcatcaag atggaggttt gcttctgaat aacccttcgg cattagctat gcatgagtgt     2460

aaatgtcttt ggccagatgt gccgttagag tgcatagtat ccctgggcac tggacgttat     2520

gagagtgatg tgagaaacac ggtaacatac acaagcttga aaactaaact ttctaatgtt     2580

atcaacagtg ctacagatac agaagaagtc catataatgc ttgatggcct gttacctcct     2640

gacacctatt ttagattcaa tcctgtaatg tgtgaaaaca tacctctaga tgaaagtcga     2700

aatgaaaagc tggatcagct gcagttggaa gggttgaaat acatagaaag aaatgaacaa     2760

aaaatgaaaa aagttgcaaa aatattaagt caagaaaaaa caactctgca gaaaattaat     2820

gattggataa aattaaaaac tgatatgtat gaaggacttc cattcttttc aaaattgtga     2880

tgagtatatg cttatgttct cataaatgaa ggtctgttta gaagatcaac cacattcaat     2940

aaggaattgt ggggttcgac atgagttaac tttgaaatac gtatgaattc tggagaatcc     3000

tgaaaaagac ggtgcttcaa ccagcttgca tagcacagag aatattcttg gttacagaat     3060

tcatatggga actaggcttt taagatgtta ataattagct aagctttagt aacccttact     3120

gtgctagtag attttagtag atattggtgt tatattgttt gatgtttgaa aatatattaa     3180

tatatgtgcc gaacaagaaa ccgaaagcta tattgtactg tgtattttta ctttagtcct     3240

cataatcatg ttgaatttat gtgatcattg attttatttc atatggaaaa gctaatttct     3300

tcttaaattt acattaccta atattctcac tagctatgtt ctccaatcca cactgccttt     3360

tattgtaata tcatctaaat agatgcagaa aaatggaatt ttctctatta aagtatttta     3420

catttgacat aaaaaagaac cagatacagt tttctattca gatatgttta ttttaacatt     3480

gtttggttaa aaaaggtgaa gttccagtca accacttttt acccctgaaa tttcaagata     3540

atgctatatt aacttttcca gatctaacac tagcttattc ttccctgtta taaaatggtt     3600

tgaacttact gaggagatat tcctatcatt aacaaaaata aactatttaa ataatctgtt     3660

gttaaaaggc taatgtcatt ttaaaattaa tttttgttca taatgtagct cccctttagc     3720

ctttgaatac acctggcagc agtatgctta aaaataagaa gttagttgcc tggcgcagta     3780

gctcacacct gtaatcccag cactttggga ggccgaggca ggcagatcac ctgacgtcag     3840

gagtccaaga ccagcctggc caacacggtg aaacctcgtc tctaataaaa atacaaacat     3900

tagcccggca tggtggtgca cacctatagt cccagctact cgggaggcta aggcaggaga     3960

atggcttgaa cctgagagac ggaggttgca gtgagccaaa tagcgccagt gcactccagc     4020

ctaggcgaca cagcgagact ccatctcaaa aaaaaaaaaa aaaaaaagaa gaagttaggc     4080

ttgttttacc ttattaactc ctttgaactg tctggatttc atggaagttg gtaagatgca     4140

cttacatgga acattgttca tgccaaacaa actcatcttt attgtatcta tttgtcacat     4200

aaatccttac atggaatgtt ttgatttctt aagaaaaatg aaacaaaggt tagcgcccct     4260

tgttttagac atacaaacta aagctagacc ctgttgccca gatagtcata ttgcttcttt     4320

gcaatatcaa ttcacagagg ctgtgagatg tggttcaaag agtggagtcg agagtctgga     4380

tgctaatcct gcctttgctg caagaaccct tctgtttgtt accttgagga aggcaaatgt     4440

ctgtaggctt tgcatatctc atttgtaaaa tgaggaaagg tagctgtaaa attttctaac     4500

atccgaatta tataaacttt agacatagta taaaatagga aactaccaat gatttctaaa     4560

gataatatag ttctttcaga ccacaaataa tacataataa catgcaacta agaacaactt     4620

gtaaatgcaa gaaaaaaaca aataattgga aatcagaata tttctgggaa ttcttcgtaa     4680

taaagcaaat ttcaagcaca ataaagtaat atttatgcat atttacatat ttgcacctca     4740

tcataaggtc actctagtcc taaactgatg tagttcatct gttttacagc tgaagttaag     4800

tatgtccctt atttgtgctt ggcttatttc tttcttaaat aatacattac acaagtgaaa     4860

aaaaaaaaa                                                             4869


<210>  124
<211>  7563
<212>  DNA
<213>  homo sapiens

<400>  124
aaaagtagtt tgtctttact aggccaccgt ctcgtcagcg ttacggagta ttttgtccgc       60

ctgccgccgc cgtcccagat attaatcacg gagttccagg gagaaggaac ttgtgaaatg      120

ggggagccgg ctggggttgc cggcaccatg gagtcacctt ttagcccggg actctttcac      180

aggctggatg aagattggga ttctgctctc tttgctgaac tcggttattt cacagacact      240

gatgagctgc aattggaagc agcaaatgag acgtatgaaa acaattttga taatcttgat      300

tttgatttgg atttgatgcc ttgggagtca gacatttggg acatcaacaa ccaaatctgt      360

acagttaaag atattaaggc agaacctcag ccactttctc cagcctcctc aagttattca      420

gtctcgtctc ctcggtcagt ggactcttat tcttcaactc agcatgttcc tgaggagttg      480

gatttgtctt ctagttctca gatgtctccc ctttccttat atggtgaaaa ctctaatagt      540

ctctcttcag cggagccact gaaggaagat aagcctgtca ctggtcctag gaacaagact      600

gaaaatggac tgactccaaa gaaaaaaatt caggtgaatt caaaaccttc aattcagccc      660

aagcctttat tgcttccagc agcacccaag actcaaacaa actccagtgt tccagcaaaa      720

accatcatta ttcagacagt accaacgctt atgccattgg caaagcagca accaattatc      780

agtttacaac ctgcacccac taaaggccag acggttttgc tgtctcagcc tactgtggta      840

caacttcaag cacctggagt tctgccctct gctcagccag tccttgctgt tgctggggga      900

gtcacacagc tccctaatca cgtggtgaat gtggtaccag ccccttcagc gaatagccca      960

gtgaatggaa aactttccgt gactaaacct gtcctacaaa gtaccatgag aaatgtcggt     1020

tcagatattg ctgtgctaag gagacagcaa cgtatgataa aaaatcgaga atccgcttgt     1080

cagtctcgca agaagaagaa agaatatatg ctagggttag aggcgagatt aaaggctgcc     1140

ctctcagaaa acgagcaact gaagaaagaa aatggaacac tgaagcggca gctggatgaa     1200

gttgtgtcag agaaccagag gcttaaagtc cctagtccaa agcgaagagt tgtctgtgtg     1260

atgatagtat tggcatttat aatactgaac tatggaccta tgagcatgtt ggaacaggat     1320

tccaggagaa tgaaccctag tgtgagccct gcaaatcaaa ggaggcacct tctaggattt     1380

tctgctaaag aggcacagga cacatcagat ggtattatcc agaaaaacag ctacagatat     1440

gatcattctg tttcaaatga caaagccctg atggtgctaa ctgaagaacc attgctttac     1500

attcctccac ctccttgtca gcccctaatt aacacaacag agtctctcag gttaaatcat     1560

gaacttcgag gatgggttca tagacatgaa gtagaaagga ccaagtcaag aagaatgaca     1620

aataatcaac agaaaacccg tattcttcag ggtgctctgg aacagggctc aaattctcag     1680

ctgatggctg ttcaatacac agaaaccact agtagtatca gcaggaactc agggagtgag     1740

ctacaagtgt attatgcttc acccagaagt tatcaagact tttttgaagc catccgcaga     1800

aggggagaca cattttatgt tgtgtcattt cgaagggatc acctgctgtt accagctacc     1860

acccataaca agaccacaag accaaaaatg tcaattgtgt taccagcaat aaacataaat     1920

gagaatgtga tcaatgggca ggactacgaa gtgatgatgc agattgactg tcaggtgatg     1980

gacaccagga tcctccatat caaaagttcg tcagttcctc cttacctccg agatcagcag     2040

aggaatcaaa ccaacacctt ctttggctcc cctcccgcag ccacagaggc aacccacgtt     2100

gtcagcacca tccctgagtc attacaatag caccctgcag ctatgctgga aaactgagcg     2160

tgggaccctg ccagactgaa gagcaggtga gcaaaatgct gctttctgcc ttggtggcag     2220

gcagagaact gtctcgtact agaattcaag gaggaaagaa gaagaaataa aagaagctgc     2280

tccatttttc atcatctacc catctatttg gaaagcactg gaattcagat gcaagagaac     2340

aatgtttctt cagtggcaaa tgtagccctg catcctccag tgttacctgg tgtagatttt     2400

tttttctgta cctttctaaa cctctcttcc ctctgtgatg gttttgtgtt taaacagtca     2460

tcttctttta aataatatcc acctctcctt tttgccattt cacttattga ttcataaagt     2520

gaattttatt taaagctatg ccacacatgc atgttcaaat ggtttccact gattcgattt     2580

ttcattcatt taatgcaaac ccattctgga tattgtgctt atttgagaaa acacatttca     2640

aaaccagaaa agccaaaaac actccaaaaa caagcaaaac aatttggagc tttagataaa     2700

aggaaaaact cccagttggt aaagtttatc tttacttagg atttgtggct cacacctaaa     2760

caaagggggt cagggagtgg gtacaaattt gagaaaatag aagggtaagg gaagggccag     2820

tggtggggtt tggagagagg agatagctcc attaatacac atgtttaaaa gatggaaagt     2880

tcacgcctgt aatcccagca ctttgggagg ccgaggcggg tggatcacga ggtcaggaga     2940

tcaagaccat cccggctaaa acggtgaaac cccgtctcta ctaaaaatac aaaaaattag     3000

ccgggcgtag tgacgggcgc ctgtagtccc agctacttgg gaggctgagg caggagaatg     3060

gcgtgaaccc gggaggcgga gcttgcagtg agccgagatc ccgccactgc actccagcct     3120

gggcgacaga gcgagactcc gtctcaaaaa aaaaaaaaaa aaaaaaaaaa gatggaaagt     3180

tcgatgtgac tgcagtatga gattaaagcc acaactattg tttattttgg ggactctagg     3240

ccaccaagta ttagcacaca tacttatgtt ttctctacta atctggtcca ggtcctcatg     3300

gaccacagga caaagctttc attttcattc attcttctat tgaaattata ccaaattcag     3360

ctgaggaata tggaagtaac tttagactta aacaagacaa aagttttttc actgaagaat     3420

tgacaagtat ttgctcctta aaacaacgca gattagtgaa cgtggattcc tgctgaggga     3480

gtgcatccca taatatggca ataattttca gtttctccaa cgaaaagata gtgaaggaat     3540

taaatctttt gtcctcccat ggttaaaaaa aaaaaaaaag ctgtgttcat ttttactgta     3600

ctatgcctct tttttcacca tagtagacaa ttatgtttca tttgatgaat tcatagaact     3660

ggatctcata cagcgatgtc ctctctaatg ttctaccttt cagtttctaa agtgagtctt     3720

cctccctctc ctacaaaact tttcaatttt ttgatgtaac tcatctacaa atactgtttc     3780

ttaccccagt tgacttgcct ttgtcagatt tcttcttgtt ccacactata gcaatcaatt     3840

tctcttcttc cttacaagaa agggaacgag aaattgtagc aacctctcaa ggattatatg     3900

cagctagtta gttttctgcc tgtgaaatta ggtctggctc ctaaataatt ttaaagaacc     3960

atcagcactt ctaactctct ggacaggtgc ctctttgtcc aagctagtta aatgctttcc     4020

aaggaaatca gttcaacttt tgtgagcggg gaaaagcagg gctttattgt tgtgttacct     4080

gggagtctgg agtttgaaaa gtgctaatta accttcctct ttttccacat tacaaacctt     4140

tttaagcagc gcagcactcc ccttagattt ggctatcctg ggtgattttc agacaagaac     4200

cattttctct ggggaccatt cttctgctgg gtgccaagga atataaggca aatgcccaga     4260

agaccttcag gtgactgggc agtcttatca tgggatattt cttctggccc tgccccttcc     4320

cattctgtaa tgtgaattag ccacaccaga ggctgtgacc atggctagta gacagtggca     4380

acatagtcat ccccaagatg ctaatcttct gctggaactg tcatacgtta tcatggtcaa     4440

tgtaaacctg gtttgtgtgg ggtgattata aatagagttt ccctcctctc tgtgacagaa     4500

tcacaggaga aggacccatc tcgtggcctt cttgttctta gcgcttcact tttacttcat     4560

ccctcgattc ccagcttttt ctatcatcat tttgccaact cctcagatgc aagactttgg     4620

ttatgtcata ctcaccaacg ttagtccctc tcttccaggt gaaaaggtgg gtagcggttg     4680

ggagggagtc tccactgaag agcaggaagg tggtagcagg gccggcagct ctgccacaga     4740

gctaggggtg cctgtaaggt gccgcctaga gcagcctggg agctttgcct tcttttgtct     4800

ctcactagcc cttctactct ttgtcattgc ctgttcttga gtggatcttt gaaatgaggg     4860

gacaggattc tcctaagggt agagtttcag gaaatgagtg aaaggcaatt gacaaatgca     4920

aagaagtagt cactttttaa attgctggca aagctataat taatccctag gcacaattgt     4980

agtttttatt ttaatgtttg tatgcacaag gccctttagg aaatgagaag ttgccatgcc     5040

agattaattt tttttttttt ttttggtggg attgcctttt gggggttgca gccagaaatt     5100

gtgggtaatg tgtgtatttt tttatttatt aaattttaaa caggattgtg caagcttatg     5160

agacaattag ataaactcat ggaggaggca ggtcctcctg ttattagatg attttgtgct     5220

cttggggctg acaataatac actcttggga agtgatggta gagactgatg ggaatagtct     5280

ttctgcctgg ttgcaagtcc caaattttta agggttaatg gaagtaagtg gatgtttcct     5340

catgttaact actgaatcag atgttaggag cttgtccctt tggggttgac ttatgcccag     5400

cagtacaggg acacagcttc attagagtgt tagtgtaaac taactccaaa gttaggagtt     5460

aatgtgaaag gatcatcctt gaaacaaatc tgctgtttgc catgcttgta gtacagaaac     5520

ttcacatgga gttttgggtg ggatttgtgt tttcacaagt aaaaaatccc tcacgattat     5580

aaaactcaga gcatcatcta attttttttt ttaatgacta caagttccag cacaaaactg     5640

gcatttcttt gccatttctt gccagtaaga agttgacacg gaggtatttg aaagcaatgt     5700

tatgtgagtc attcttaagt gttccaagta agtttagaaa cagaaaagga acttgggatt     5760

caaattgatt tttcaaatca tttttaaaga gacatcatcc tgactaaatc ttagcctgaa     5820

ccttcctccc ctgtgtgtat tccccggtag tcaccgcagc gagatgctgg tgagactgcc     5880

gtggtggcat ttagcatcgt taaaactgga aaactctcaa gctctttgcc actttcctac     5940

tattttttga ttcttgccat tttaccaagc ttaggttgtg aaacttgaca gaaatgtatt     6000

acaggaaaaa cttataattg tatttgactt tctaacacat tgcaaagttt caaagtgact     6060

ttcactttca acaacatatt agaagtaacc acttttgctt tcacagcctg aagagttaga     6120

gcctgatctg atgccccctt tcactctgaa gtcatgggaa attttccagc catgaaagcc     6180

ctctttccac tgcatactga tgggctgact cagcttcctt cagccgactg agatcttttc     6240

atactattgg ctatttcata ccaattaacc tcttaaataa gattgtgaat tgccaaaatt     6300

gatagacact tattaccacc tgtggactcc atattcctta ccacaaatgt tattttcatc     6360

agtcctgagt cattttaact tacagaaatt aggattgttg ctgctaatat gaataccaat     6420

tataactttt agaaacaaga ataaagccta aaagagaatg aaatataaga aatgttcgtt     6480

cccaccccta ataacatttg gaagtgaata ttcccatttt cttccaccca cagggattgg     6540

gattgatttt taatttccta ggaaacaata ctagactacc caaaaagatg ttgccagaat     6600

ccaaaaggaa ctatgctcgt aaaagaaatg cagttttctc ctacctaaaa aaaagaaagt     6660

aaagtgtgtt ctgttcttat ctttttaatg actaagcttt aaacagttta ttttgggtaa     6720

gactagaact ttcggccatt tgttctaata tgtgtgttat tagatgcaat agaatttatg     6780

aaaagaagaa tgacaaaggt atctgattag aaaatttgat cttacgcatg aatccatgtc     6840

atggccagcc actgtcacat agtgggtgcc attctcaaca tattggtttg ctaactttaa     6900

gcattaggga tttagcacac taaaatactt ttaattatat taggtttggt aactaaggag     6960

taaataaatc ataatttatc atttgccaag gccaacaaac aacactattg tgctgtttgc     7020

tctcaatgaa gttgaataaa ccaggaggct tggcatatcc cctttatgtt aatcccagct     7080

agagattagt aggttgactt tcacagcaat tgtatattga tccattttaa ctcatccttg     7140

ccataatttc caggccagtc accaggacag aggagatgat ggggaaacag agctttagat     7200

gaaaactact atgcactact agccttagag gcactggttt cctgttacca ctttggcaag     7260

tatggatggt ctaagtccag tagggcttca tccatggagc cattagaact gaggggggag     7320

tgttagagat gccatttcac caggatcttt ttgctcaggt tgtacccatg ccaattgaag     7380

aacgtgttaa agatgaggag gagagatgta ccattctctc ccttaataat gatgttggtt     7440

tgcaaaacct aaagaaataa taacaacaga ctatttcata ctttcaagca agtctttata     7500

ctacctgtta tttctctaaa attcaaataa agaattttta aacttaaaaa aaaaaaaaaa     7560

aaa                                                                   7563


<210>  125
<211>  7563
<212>  DNA
<213>  homo sapiens

<400>  125
aaaagtagtt tgtctttact aggccaccgt ctcgtcagcg ttacggagta ttttgtccgc       60

ctgccgccgc cgtcccagat attaatcacg gagttccagg gagaaggaac ttgtgaaatg      120

ggggagccgg ctggggttgc cggcaccatg gagtcacctt ttagcccggg actctttcac      180

aggctggatg aagattggga ttctgctctc tttgctgaac tcggttattt cacagacact      240

gatgagctgc aattggaagc agcaaatgag acgtatgaaa acaattttga taatcttgat      300

tttgatttgg atttgatgcc ttgggagtca gacatttggg acatcaacaa ccaaatctgt      360

acagttaaag atattaaggc agaacctcag ccactttctc cagcctcctc aagttattca      420

gtctcgtctc ctcggtcagt ggactcttat tcttcaactc agcatgttcc tgaggagttg      480

gatttgtctt ctagttctca gatgtctccc ctttccttat atggtgaaaa ctctaatagt      540

ctctcttcag cggagccact gaaggaagat aagcctgtca ctggtcctag gaacaagact      600

gaaaatggac tgactccaaa gaaaaaaatt caggtgaatt caaaaccttc aattcagccc      660

aagcctttat tgcttccagc agcacccaag actcaaacaa actccagtgt tccagcaaaa      720

accatcatta ttcagacagt accaacgctt atgccattgg caaagcagca accaattatc      780

agtttacaac ctgcacccac taaaggccag acggttttgc tgtctcagcc tactgtggta      840

caacttcaag cacctggagt tctgccctct gctcagccag tccttgctgt tgctggggga      900

gtcacacagc tccctaatca cgtggtgaat gtggtaccag ccccttcagc gaatagccca      960

gtgaatggaa aactttccgt gactaaacct gtcctacaaa gtaccatgag aaatgtcggt     1020

tcagatattg ctgtgctaag gagacagcaa cgtatgataa aaaatcgaga atccgcttgt     1080

cagtctcgca agaagaagaa agaatatatg ctagggttag aggcgagatt aaaggctgcc     1140

ctctcagaaa acgagcaact gaagaaagaa aatggaacac tgaagcggca gctggatgaa     1200

gttgtgtcag agaaccagag gcttaaagtc cctagtccaa agcgaagagt tgtctgtgtg     1260

atgatagtat tggcatttat aatactgaac tatggaccta tgagcatgtt ggaacaggat     1320

tccaggagaa tgaaccctag tgtgagccct gcaaatcaaa ggaggcacct tctaggattt     1380

tctgctaaag aggcacagga cacatcagat ggtattatcc agaaaaacag ctacagatat     1440

gatcattctg tttcaaatga caaagccctg atggtgctaa ctgaagaacc attgctttac     1500

attcctccac ctccttgtca gcccctaatt aacacaacag agtctctcag gttaaatcat     1560

gaacttcgag gatgggttca tagacatgaa gtagaaagga ccaagtcaag aagaatgaca     1620

aataatcaac agaaaacccg tattcttcag ggtgctctgg aacagggctc aaattctcag     1680

ctgatggctg ttcaatacac agaaaccact agtagtatca gcaggaactc agggagtgag     1740

ctacaagtgt attatgcttc acccagaagt tatcaagact tttttgaagc catccgcaga     1800

aggggagaca cattttatgt tgtgtcattt cgaagggatc acctgctgtt accagctacc     1860

acccataaca agaccacaag accaaaaatg tcaattgtgt taccagcaat aaacataaat     1920

gagaatgtga tcaatgggca ggactacgaa gtgatgatgc agattgactg tcaggtgatg     1980

gacaccagga tcctccatat caaaagttcg tcagttcctc cttacctccg agatcagcag     2040

aggaatcaaa ccaacacctt ctttggctcc cctcccgcag ccacagaggc aacccacgtt     2100

gtcagcacca tccctgagtc attacaatag caccctgcag ctatgctgga aaactgagcg     2160

tgggaccctg ccagactgaa gagcaggtga gcaaaatgct gctttctgcc ttggtggcag     2220

gcagagaact gtctcgtact agaattcaag gaggaaagaa gaagaaataa aagaagctgc     2280

tccatttttc atcatctacc catctatttg gaaagcactg gaattcagat gcaagagaac     2340

aatgtttctt cagtggcaaa tgtagccctg catcctccag tgttacctgg tgtagatttt     2400

tttttctgta cctttctaaa cctctcttcc ctctgtgatg gttttgtgtt taaacagtca     2460

tcttctttta aataatatcc acctctcctt tttgccattt cacttattga ttcataaagt     2520

gaattttatt taaagctatg ccacacatgc atgttcaaat ggtttccact gattcgattt     2580

ttcattcatt taatgcaaac ccattctgga tattgtgctt atttgagaaa acacatttca     2640

aaaccagaaa agccaaaaac actccaaaaa caagcaaaac aatttggagc tttagataaa     2700

aggaaaaact cccagttggt aaagtttatc tttacttagg atttgtggct cacacctaaa     2760

caaagggggt cagggagtgg gtacaaattt gagaaaatag aagggtaagg gaagggccag     2820

tggtggggtt tggagagagg agatagctcc attaatacac atgtttaaaa gatggaaagt     2880

tcacgcctgt aatcccagca ctttgggagg ccgaggcggg tggatcacga ggtcaggaga     2940

tcaagaccat cccggctaaa acggtgaaac cccgtctcta ctaaaaatac aaaaaattag     3000

ccgggcgtag tgacgggcgc ctgtagtccc agctacttgg gaggctgagg caggagaatg     3060

gcgtgaaccc gggaggcgga gcttgcagtg agccgagatc ccgccactgc actccagcct     3120

gggcgacaga gcgagactcc gtctcaaaaa aaaaaaaaaa aaaaaaaaaa gatggaaagt     3180

tcgatgtgac tgcagtatga gattaaagcc acaactattg tttattttgg ggactctagg     3240

ccaccaagta ttagcacaca tacttatgtt ttctctacta atctggtcca ggtcctcatg     3300

gaccacagga caaagctttc attttcattc attcttctat tgaaattata ccaaattcag     3360

ctgaggaata tggaagtaac tttagactta aacaagacaa aagttttttc actgaagaat     3420

tgacaagtat ttgctcctta aaacaacgca gattagtgaa cgtggattcc tgctgaggga     3480

gtgcatccca taatatggca ataattttca gtttctccaa cgaaaagata gtgaaggaat     3540

taaatctttt gtcctcccat ggttaaaaaa aaaaaaaaag ctgtgttcat ttttactgta     3600

ctatgcctct tttttcacca tagtagacaa ttatgtttca tttgatgaat tcatagaact     3660

ggatctcata cagcgatgtc ctctctaatg ttctaccttt cagtttctaa agtgagtctt     3720

cctccctctc ctacaaaact tttcaatttt ttgatgtaac tcatctacaa atactgtttc     3780

ttaccccagt tgacttgcct ttgtcagatt tcttcttgtt ccacactata gcaatcaatt     3840

tctcttcttc cttacaagaa agggaacgag aaattgtagc aacctctcaa ggattatatg     3900

cagctagtta gttttctgcc tgtgaaatta ggtctggctc ctaaataatt ttaaagaacc     3960

atcagcactt ctaactctct ggacaggtgc ctctttgtcc aagctagtta aatgctttcc     4020

aaggaaatca gttcaacttt tgtgagcggg gaaaagcagg gctttattgt tgtgttacct     4080

gggagtctgg agtttgaaaa gtgctaatta accttcctct ttttccacat tacaaacctt     4140

tttaagcagc gcagcactcc ccttagattt ggctatcctg ggtgattttc agacaagaac     4200

cattttctct ggggaccatt cttctgctgg gtgccaagga atataaggca aatgcccaga     4260

agaccttcag gtgactgggc agtcttatca tgggatattt cttctggccc tgccccttcc     4320

cattctgtaa tgtgaattag ccacaccaga ggctgtgacc atggctagta gacagtggca     4380

acatagtcat ccccaagatg ctaatcttct gctggaactg tcatacgtta tcatggtcaa     4440

tgtaaacctg gtttgtgtgg ggtgattata aatagagttt ccctcctctc tgtgacagaa     4500

tcacaggaga aggacccatc tcgtggcctt cttgttctta gcgcttcact tttacttcat     4560

ccctcgattc ccagcttttt ctatcatcat tttgccaact cctcagatgc aagactttgg     4620

ttatgtcata ctcaccaacg ttagtccctc tcttccaggt gaaaaggtgg gtagcggttg     4680

ggagggagtc tccactgaag agcaggaagg tggtagcagg gccggcagct ctgccacaga     4740

gctaggggtg cctgtaaggt gccgcctaga gcagcctggg agctttgcct tcttttgtct     4800

ctcactagcc cttctactct ttgtcattgc ctgttcttga gtggatcttt gaaatgaggg     4860

gacaggattc tcctaagggt agagtttcag gaaatgagtg aaaggcaatt gacaaatgca     4920

aagaagtagt cactttttaa attgctggca aagctataat taatccctag gcacaattgt     4980

agtttttatt ttaatgtttg tatgcacaag gccctttagg aaatgagaag ttgccatgcc     5040

agattaattt tttttttttt ttttggtggg attgcctttt gggggttgca gccagaaatt     5100

gtgggtaatg tgtgtatttt tttatttatt aaattttaaa caggattgtg caagcttatg     5160

agacaattag ataaactcat ggaggaggca ggtcctcctg ttattagatg attttgtgct     5220

cttggggctg acaataatac actcttggga agtgatggta gagactgatg ggaatagtct     5280

ttctgcctgg ttgcaagtcc caaattttta agggttaatg gaagtaagtg gatgtttcct     5340

catgttaact actgaatcag atgttaggag cttgtccctt tggggttgac ttatgcccag     5400

cagtacaggg acacagcttc attagagtgt tagtgtaaac taactccaaa gttaggagtt     5460

aatgtgaaag gatcatcctt gaaacaaatc tgctgtttgc catgcttgta gtacagaaac     5520

ttcacatgga gttttgggtg ggatttgtgt tttcacaagt aaaaaatccc tcacgattat     5580

aaaactcaga gcatcatcta attttttttt ttaatgacta caagttccag cacaaaactg     5640

gcatttcttt gccatttctt gccagtaaga agttgacacg gaggtatttg aaagcaatgt     5700

tatgtgagtc attcttaagt gttccaagta agtttagaaa cagaaaagga acttgggatt     5760

caaattgatt tttcaaatca tttttaaaga gacatcatcc tgactaaatc ttagcctgaa     5820

ccttcctccc ctgtgtgtat tccccggtag tcaccgcagc gagatgctgg tgagactgcc     5880

gtggtggcat ttagcatcgt taaaactgga aaactctcaa gctctttgcc actttcctac     5940

tattttttga ttcttgccat tttaccaagc ttaggttgtg aaacttgaca gaaatgtatt     6000

acaggaaaaa cttataattg tatttgactt tctaacacat tgcaaagttt caaagtgact     6060

ttcactttca acaacatatt agaagtaacc acttttgctt tcacagcctg aagagttaga     6120

gcctgatctg atgccccctt tcactctgaa gtcatgggaa attttccagc catgaaagcc     6180

ctctttccac tgcatactga tgggctgact cagcttcctt cagccgactg agatcttttc     6240

atactattgg ctatttcata ccaattaacc tcttaaataa gattgtgaat tgccaaaatt     6300

gatagacact tattaccacc tgtggactcc atattcctta ccacaaatgt tattttcatc     6360

agtcctgagt cattttaact tacagaaatt aggattgttg ctgctaatat gaataccaat     6420

tataactttt agaaacaaga ataaagccta aaagagaatg aaatataaga aatgttcgtt     6480

cccaccccta ataacatttg gaagtgaata ttcccatttt cttccaccca cagggattgg     6540

gattgatttt taatttccta ggaaacaata ctagactacc caaaaagatg ttgccagaat     6600

ccaaaaggaa ctatgctcgt aaaagaaatg cagttttctc ctacctaaaa aaaagaaagt     6660

aaagtgtgtt ctgttcttat ctttttaatg actaagcttt aaacagttta ttttgggtaa     6720

gactagaact ttcggccatt tgttctaata tgtgtgttat tagatgcaat agaatttatg     6780

aaaagaagaa tgacaaaggt atctgattag aaaatttgat cttacgcatg aatccatgtc     6840

atggccagcc actgtcacat agtgggtgcc attctcaaca tattggtttg ctaactttaa     6900

gcattaggga tttagcacac taaaatactt ttaattatat taggtttggt aactaaggag     6960

taaataaatc ataatttatc atttgccaag gccaacaaac aacactattg tgctgtttgc     7020

tctcaatgaa gttgaataaa ccaggaggct tggcatatcc cctttatgtt aatcccagct     7080

agagattagt aggttgactt tcacagcaat tgtatattga tccattttaa ctcatccttg     7140

ccataatttc caggccagtc accaggacag aggagatgat ggggaaacag agctttagat     7200

gaaaactact atgcactact agccttagag gcactggttt cctgttacca ctttggcaag     7260

tatggatggt ctaagtccag tagggcttca tccatggagc cattagaact gaggggggag     7320

tgttagagat gccatttcac caggatcttt ttgctcaggt tgtacccatg ccaattgaag     7380

aacgtgttaa agatgaggag gagagatgta ccattctctc ccttaataat gatgttggtt     7440

tgcaaaacct aaagaaataa taacaacaga ctatttcata ctttcaagca agtctttata     7500

ctacctgtta tttctctaaa attcaaataa agaattttta aacttaaaaa aaaaaaaaaa     7560

aaa                                                                   7563


<210>  126
<211>  2934
<212>  DNA
<213>  homo sapiens

<400>  126
acgccgtgtc ccggcacccc gcacccgggc acacaaaaaa cgggtcgccc gcgattctca       60

gggattgatc gcctcttcag aaaagtcctc catacatttt ctccccaatt ccattccttg      120

ggcatgccat agcatttggg aaaagtccaa ttgaatttct agaaaatgca tatgagaagt      180

atggacctgt atttagtttt accatggtag gcaagacatt tacttacctt ctggggagtg      240

atgctgctgc actgcttttt aatagtaaaa atgaagacct gaatgcagaa gatgtctaca      300

gtcgcctgac aacacctgtg tttgggaagg gagttgcata cgatgtgcct aatccagttt      360

tcttggagca gaagaaaatg ttaaaaagtg gccttaacat agcccacttt aaacagcatg      420

tttctataat tgaaaaagaa acaaaggaat actttgagag ttggggagaa agtggagaaa      480

aaaatgtgtt tgaagctctt tctgagctca taattttaac agctagccat tgtttgcatg      540

gaaaggaaat cagaagtcaa ctcaatgaaa aggtagcaca gctgtatgca gatttggatg      600

gaggtttcag ccatgcagcc tggctcttac caggttggct gcctttgcct agtttcagac      660

gcagggacag agctcatcgg gaaatcaagg atattttcta taaggcaatc cagaaacgca      720

gacagtctca agaaaaaatt gatgacattc tccaaacttt actagatgct acatacaagg      780

atgggcgtcc tttgactgat gatgaagtag cagggatgct tattggatta ctcttggcag      840

ggcagcatac atcctcaact actagtgctt ggatgggctt ctttttggcc agagacaaaa      900

cacttcaaaa aaaatgttat ttagaacaga aaacagtctg tggagagaat ctgcctcctt      960

taacttatga ccagctcaag gatctaaatt tacttgatcg ctgtataaaa gaaacattaa     1020

gacttagacc tcctataatg atcatgatga gaatggccag aactcctcag actgtggcag     1080

ggtataccat tcctccagga catcaggtgt gtgtttctcc cactgtcaat caaagactta     1140

aagactcatg ggtagaacgc ctggacttta atcctgatcg ctacttacag gataacccag     1200

catcagggga aaagtttgcc tatgtgccat ttggagctgg gcgtcatcgt tgtattgggg     1260

aaaattttgc ctatgttcaa attaagacaa tttggtccac tatgcttcgt ttatatgaat     1320

ttgatctcat tgatggatac tttcccactg tgaattatac aactatgatt cacacccctg     1380

aaaacccagt tatccgttac aaacgaagat caaaatgaaa aaggttgcaa ggaacgaata     1440

tatgtgatta tcactgtaag ccacaaaggc attcgaagag aatgaagtgt acaaaacaac     1500

tcttgtagtt tactgttttt ttaagtgtgt aattctaaaa gccagtttat gatttaggat     1560

tttgttaact gaatggttct atcaaatata atagcatttg aaacattttc taatagttat     1620

gatacttata catgtgcttt caggaagttc cttggtgaaa caattgttga ggggggatct     1680

aggtaattgg cagattctaa ataatataat ttccagatag taattttaag agtactcatc     1740

gctcttgcca aataagttca gggtattcaa atcttggact agtcctgcaa ggtataaaga     1800

ataaaaatcc cagtgagata cttggaaacc acagtttatt attatttatc tgggcaatta     1860

ttgtgtgtgt gaggatggaa gggtagggaa taatcgaaca tctaaagcct tgaataagag     1920

aatactaatt gttttggtat gatgatactc agaaatggag atattatagg aaaaagaaat     1980

cctttggaat tttaactaaa atcactgcat atgggaaatt aagagatcca ggaccatatt     2040

tgataagagt tcctaaaaat aatgtaatta ttaatgctaa agactgctca tgtatcttga     2100

tctaattact aaataattac atatttattt acctgataaa tatgtatcta gttctacaag     2160

gtcacattta tgtggaagtc caaagtcaag tccttagggg ataattttgt tttggctcag     2220

ttgttccctg cttccttttt tttttttttt ttttgagatg gagtctcgct ctgttgccca     2280

ggctggagtg cagtggtgcg atctcagctc actgcatcct ctgcctcccg ggttcaagca     2340

attctctgcc tcagcctccc aagtagttgg gattacaggc acctgccacc atgcctggct     2400

aattttttgt atttttagta gagacggggg tttcactatg ttggctaggc tggtcttgaa     2460

ctcctgacct cgtgatccac ccgccttggc ctcccaaagt gctgggatta caggcatgag     2520

ccaccgcacc tggccttccc tgcttcctct ctagaatcca attagggatg tttgttacta     2580

ctcatattga ttaaaacagt taacaaactt ttttcttttt aaaatgtgag atcagtgaac     2640

tctggtttta agataatctg aaacaaggtc cttgggagta ataaaattgg tcacattctg     2700

taaagcacat tctgtttagg aatcaactta tctcaaattg taactcgggg cctaactata     2760

tgagatggct gaaaaaatac cacatcgtct gttttcacta ggtgatgcca aaatattttg     2820

ctttatgtat attacagttc tttttaaaac actggaagac tcatgttaaa ctctaattgt     2880

gaaggcagaa tctctgctaa tttttcagat taaaattctc tttgaaaaaa taca           2934


<210>  127
<211>  7431
<212>  DNA
<213>  homo sapiens

<400>  127
cgcgcgcccg ggggagcgca gagtttggaa agtcttcgag aagcttcaga ggagggaagg       60

gggtgggaag agtgggggtg caagagagaa aaacccgcct cttgcgagtt gagcgaggaa      120

gagggggggg aaggctccga gttccgcttc ctgaacggcg ggtggataga gaaggttggc      180

gcggggaaga ccggcgggag gcgcgccccg ggcccgcggc gcgattggcg tgaccggcga      240

tggccggtga gcggacccgc aggttcaccc ggagcctgtt gagacctggg caggcggccg      300

agctccggca cagcgccgcg tccgccgccg cggtggcagt cagcagccgg cagcagcagc      360

ggcaagaaaa gcctaggctt ctcgagcctt tggattatga gactgtcatt gaagaacttg      420

aaaagaccta ccggaatgat cctcttcaag atctcttgtt cttccccagt gatgactttt      480

cagcagccac agtttcctgg gatatccgca cgttgtactc aacagtacct gaagatgcag      540

agcacaaggc agaaaattta ctggttaagg aggcttgtaa attttatagt tcccagtggc      600

atgtggtaaa ctacaaatat gaacaatatt ctggagacat tcgacagcta ccccgagcag      660

aatacaaacc agagaagctt ccttcacatt cctttgagat tgaccatgaa gatgctgata      720

aggatgaaga taccacttcc cactcgtctt ccaagggggg tggaggagcg ggaggaactg      780

gtgttttcaa gtccggctgg ctctacaagg ggaattttaa cagcaccgtg aacaacaccg      840

ttactgttcg gtcattcaaa aagcgctact tccagctgac tcagttacca gataactcct      900

acattatgaa cttttacaaa gatgagaaaa tatccaaaga acccaaagga tgcatctttt      960

tggattcctg tacaggagtg gtgcagaata acagactaag aaaatatgcc tttgaattga     1020

aaatgaatga tctgacctat tttgtgctgg cagctgaaac agagtcagat atggatgaat     1080

ggatccacac cctcaaccgc attctgcaaa tcagtcctga ggggcccctc caagggagga     1140

ggagcacaga gctcactgat ctgggtctgg attcgctgga taattctgta acttgtgaat     1200

gcacgccaga ggaaacagat tcttcagaga acaacctaca cgcagacttt gcaaagtacc     1260

tcacagaaac agaagatact gtaaaaacaa ctcgaaacat ggagaggcta aatctgttct     1320

ctctagatcc agacatagat accttgaaac ttcaaaaaaa agatctcttg gaacctgagt     1380

ctgtgatcaa accatttgaa gaaaaagctg ccaagagaat catgatcatc tgtaaagccc     1440

tcaactcaaa tcttcaggga tgtgttacgg agaatgaaaa tgatccgata acgaatattg     1500

agcctttttt tgtgagtgtg gcactttatg acctcagaga cagcaggaag atttctgctg     1560

attttcatgt ggatctaaac catgctgctg tcagacagat gctcttgggg gcttctgtgg     1620

ctttggaaaa tggcaacatc gacaccatca ctccaagaca atcagaagaa cctcacatca     1680

agggacttcc agaggaatgg ctaaaatttc caaagcaggc tgtattttct gtaagcaatc     1740

cacattctga aattgttttg gtggccaaaa tcgaaaaagt cttgatggga aacattgcaa     1800

gtggtgccga accttatatt aagaacccag actccaacaa gtatgcacaa aagatactaa     1860

aatccaacag acaattctgc agcaaattgg gaaaataccg tatgcctttt gcttgggcag     1920

taagatcagt atttaaggac aaccagggaa atgtggacag agactcaaga ttttcaccat     1980

tgtttagaca agaaagtagc aagatttcaa ctgaggacct agttaaacta gtatcagatt     2040

atagaagggc cgacagaata agcaaaatgc agaccattcc tggaagcctg gatattgctg     2100

ttgacaacgt tcccttggag catccaaatt gtgtaacatc gtcctttatc cctgtcaagc     2160

ctttcaacat gatggctcaa acagaaccca cagtggaggt ggaagaattt gtttacgatt     2220

caacaaagta ttgtcggcct tacagagtat ataaaaatca aatttatatt taccccaaac     2280

acctcaagta tgatagccag aaatgcttca acaaggcacg gaatataact gtgtgcattg     2340

aattcaaaaa ttcagatgaa gaaagtgcca agcccctgaa gtgtatttat ggaaaacctg     2400

gagggcccct cttcacctca gccgcctaca cagcagttct gcaccactct cagaatccgg     2460

atttctcaga tgaggtgaaa attgagctac caacacaact ccatgagaaa caccatattt     2520

tgttttcttt ttatcacgtc acctgtgaca tcaatgcaaa agctaatgcc aaaaagaagg     2580

aggctctgga aacgtcagtt ggatatgctt ggcttcctct gatgaaacac gatcagatag     2640

cttctcaaga gtacaacatc ccaatagcaa caagtctgcc tcctaattat ttaagctttc     2700

aagattctgc aagtggaaag catggtggga gtgacattaa atgggttgat ggtggcaaac     2760

cacttttcaa agtgtcgaca tttgttgtat caacagtaaa tactcaggat ccacatgtga     2820

atgcattttt ccaagagtgc caaaaaagag agaaagatat gtctcagtca cctacctcaa     2880

atttcatccg ctcttgtaag aacttattga atgtggaaaa gattcatgca atcatgagtt     2940

ttctgcctat aattttgaat cagctcttca aagttctggt acagaatgag gaagatgaaa     3000

taactacaac tgtcaccagg gttctgaccg acattgtggc caagtgccat gaggagcagc     3060

tggatcattc tgtccagtca tatattaagt tcgtgttcaa gaccagggca tgcaaggaga     3120

ggactgtaca tgaggaactg gctaaaaatg tgactggtct tttgaaatca aatgactcaa     3180

caacagtaaa gcatgtccta aagcattcct ggttcttctt tgcaattatc ctaaaatcga     3240

tggcacagca cttgattgac acaaataaaa tccagcttcc ccggcctcag agatttcctg     3300

aatcttacca aaatgaattg gacaatcttg tcatggtcct atccgaccat gtgatttgga     3360

aatacaagga tgcacttgaa gaaacaagaa gggcaaacca cagcgttgcc agatttctca     3420

agcgctgctt tacatttatg gaccgagggt atgtgtttaa gatggtcaac aattacatca     3480

gcatgttctc ctccggtgac cttaagacct tgtgccagta taaatttgat tttcttcaag     3540

aagtatgtca acatgaacac tttatccctt tgtgtctgcc cataagatca gcaaacattc     3600

cagatccttt gacaccttca gaatcgactc aagagttaca tgcatcagat atgcctgaat     3660

attcagtcac aaatgaattt tgtcgcaaac acttcttaat cggaattctg ctccgagaag     3720

ttggctttgc cctgcaggaa gaccaagatg tcagacactt agctttagct gtcctaaaaa     3780

atctaatggc taagcattca tttgatgatc gatacagaga gccaagaaag caggcccaga     3840

tagcaagttt atacatgccc ctgtacggca tgctcctgga caatatgcca aggatttatc     3900

tgaaggacct gtatcctttt actgtcaata catctaatca ggggtctaga gatgatctaa     3960

gcaccaatgg aggatttcaa agccagacag ctatcaaaca tgcaaactct gtggatacat     4020

cattttctaa agatgtttta aattccatag cagcattttc atcaatagct atttctacag     4080

taaaccatgc tgactccaga gcatctttag caagtcttga ctccaatcca agtaccaatg     4140

agaagagcag tgagaagacg gacaactgtg aaaagatccc aagacccttg tctttgattg     4200

gctcaactct tcgatttgac aagttagatc aagcagaaac caggagtctc ctgatgtgtt     4260

ttcttcacat tatgaaaacg atttcgtacg agactctgat tgcctactgg cagagagctc     4320

ccagcccaga ggtgtccgac ttcttcagca tcttggacgt ttgtcttcaa aatttcagat     4380

acctaggaaa acgcaacata ataagaaaaa ttgctgctgc atttaaattt gtgcagtcca     4440

cccagaacaa tggaactctc aaaggatcca atccttcctg ccagacatca ggtctcttgt     4500

cacaatggat gcactccact tccagtcatg aaggccataa gcagcacaga tcacaaactt     4560

tacctataat tcgaggcaaa aatgcacttt ctaaccccaa actcttacag atgttagaca     4620

ataccatgac cagcaactcc aatgaaatag acatcgtgca tcatgtagac actgaggcca     4680

atatagctac ggaggtttgc ctcactattc tggacctgtt atccctcttc acacagactc     4740

atcagagaca actccaacaa tgtgactgtc aaaattcatt gatgaaaagg gtctttgata     4800

cctacatgct ctttttccaa gtcaatcagt cagccacagc gctgaagcat gtgtttgcct     4860

ccttgagact gtttgtatgc aagtttcctt cagcgttctt tcaagggcct gctgacctct     4920

gtggatcatt ctgttacgaa gtcctaaaat gctgtaacca caggtcacgg tcaactcaga     4980

cagaagcctc agcccttctg tactttttca tgaggaagaa ttttgaattt aacaagcaga     5040

agtcaattgt ccggtcccac ttacaactca tcaaagctgt gagccagtta atagccgatg     5100

ctgggattgg aggctctcgg tttcaacatt cgcttgcaat taccaataat ttcgccaatg     5160

gagataagca aatgaaaaac agcaatttcc cagcagaggt gaaggacctg actaagcgta     5220

taaggactgt tttgatggcc acagctcaga tgaaggagca cgagaaggac cccgagatgc     5280

tggtggatct ccagtacagc ctggcaaact cctacgcaag cactcctgaa ctacgcagga     5340

cctggctgga aagtatggcc aagattcatg ccagaaacgg agatttatct gaggctgcca     5400

tgtgttacat ccatattgct gctctcattg cagagtatct gaaaagaaag ggttactgga     5460

aagtggaaaa gatttgcaca gcatccctgc tctcggagga tacccacccc tgtgatagca     5520

actcattact aacaactccc agtggaggaa gcatgttctc tatgggatgg ccagcttttt     5580

tgagcattac accaaacatt aaggaagaag gagcgatgaa agaggattct ggaatgcaag     5640

atacaccata caatgagaat atcctggtgg agcagctata catgtgtgtg gagtttctct     5700

ggaagtctga gcgatatgaa ctcattgctg atgtcaacaa gcccatcatt gctgtctttg     5760

agaaacaacg agacttcaaa aaattgtcag atctctacta cgacattcat cggtcatatc     5820

tgaaagtggc agaggtggtg aattcggaga agcggctgtt tggtcgctac tatcgtgtgg     5880

cattttatgg gcagggcttt tttgaagaag aagaaggtaa agagtatatt tataaagagc     5940

ctaagctgac aggtctgtcc gagatttccc aaagattact caagctctat gcagataaat     6000

ttggagcaga caatgtgaag ataatccagg attccaacaa ggtaaacccc aaggatttgg     6060

accccaaata tgcctacatc caggtgacct atgtgacgcc gttctttgag gaaaaggaaa     6120

tcgaagaccg gaagacagat ttcgaaatgc accacaacat caaccgcttt gtcttcgaga     6180

cacccttcac gctgtcgggc aagaagcacg gtggggtggc ggagcagtgc aagcggcgga     6240

cgatcctgac aacgagtcac ctgttcccct acgtgaagaa gagaatacaa gtaattagcc     6300

aatcgagcac agaactgaat ccaattgaag tggcaattga cgagatgtcc aagaaggttt     6360

ctgagcttaa tcagctttgc acaatggaag aagtggacat gatcagactg cagctcaaac     6420

tgcaaggaag tgtcagcgtg aaggttaatg ctgggccaat ggcctatgca cgagcttttc     6480

ttgaagaaac caatgcaaag aagtaccctg acaaccaagt aaagcttttg aaggagatct     6540

tcaggcaatt tgcagatgca tgtgggcagg cccttgacgt gaatgagcgc ctcatcaaag     6600

aggaccagct ggagtaccag gaagaactga ggtcccacta caaggacatg ctcagcgaac     6660

tctccacagt catgaatgag cagattacgg gcagggacga cctgtcaaag cgcggagtgg     6720

accaaacctg cactcgagta attagcaaag caactccggc cctacccacg gtctccatct     6780

catctagtgc tgaagtctga gggctctgca gcatcagacc cacctctaag agaactttct     6840

gaatttgcag ctaatctcgg ggaagagaaa gataggttta atttatttga agttttcatg     6900

gtgttaatat ttttgtttac ctcgctagct tcagaatttt gccaacctct gaatttgcac     6960

attttgtata attttttttt ctttgagcag tgttgatcaa gccaggttga atatttgcca     7020

tgaaattcca gtgaatgtgt agctcaaatg caaaccctaa gtttgctgtc agttattgta     7080

tggtcagtac cccagtccta gtacacatat tttaaaggtt aaagtgaatg tttttgtaac     7140

atttaagcat atttcagatg taaataaaag attgtaaaat atacggtttt taccaaattt     7200

aaaagatcct ttttagttaa tactatgaca gtactaaaaa tatatgaata acatttcaga     7260

taccattata ttaaaatatt tgtgtatgtg tacaaaagcg ttgataaata ctaatcttta     7320

aagtttgtgg agttccttta tttgtaatat atgtgctctt aaaagcaatg ggatgtgaaa     7380

ttatgaaagt attttattgt tcatagaaat aaaaaacaca gttactttgc a              7431


<210>  128
<211>  13804
<212>  DNA
<213>  homo sapiens

<400>  128
ggtgctcgcg aaagctcgct gtcgctggga ggcgcgcgcc ggcgttcctc ggccgctccg       60

ggtacctgag ggacgcgcgg ccgcccgcgg caggcggtgc agccccccca ccccttggag      120

ccaggcgccg gggtctgagg atagcatttc tcaagacctg acttatggag cacttgtaac      180

ctgagatatt tcagttgaag gaagaaatag ctcttctcct aagatggaat ctgtggtttg      240

ggaatgtggt tgatcaactt gatatgttgg ccaaatgtgc cccatgtaat aaaatgaaaa      300

gaagagacaa gatgatgtca ttttcccata ttgtgaaacc aaaaacaaac gccttttgtg      360

agaccaagct aacaaacctc tgacggtgcg aagagtattt aactgtttga agaatttaac      420

agtaagatac agaagaagta ccttcgagct gagacctgca ggtgtataaa tatctaaaat      480

acatattgaa taggcctgat catctgaatc tccttcagac ccaggaagga tggctatgac      540

ttggattgtc ttctctcttt ggcccttgac tgtgttcatg gggcatatag gtgggcacag      600

tttgttttct tgtgaaccta ttaccttgag gatgtgccaa gatttgcctt ataatactac      660

cttcatgcct aatcttctga atcattatga ccaacagaca gcagctttgg caatggagcc      720

attccaccct atggtgaatc tggattgttc tcgggatttc cggccttttc tttgtgcact      780

ctacgctcct atttgtatgg aatatggacg tgtcacactt ccctgtcgta ggctgtgtca      840

gcgggcttac agtgagtgtt cgaagctcat ggagatgttt ggtgttcctt ggcctgaaga      900

tatggaatgc agtaggttcc cagattgtga tgagccatat cctcgacttg tggatctgaa      960

tttagctgga gaaccaactg aaggagcccc agtggcagtg cagagagact atggtttttg     1020

gtgtccccga gagttaaaaa ttgatcctga tctgggttat tcttttctgc atgtgcgtga     1080

ttgttcacct ccttgtccaa atatgtactt cagaagagaa gaactgtcat ttgctcgcta     1140

tttcatagga ttgatttcaa tcatttgcct ctcggccaca ttgtttactt ttttaacttt     1200

tttgattgat gtcacaagat tccgttatcc tgaaaggcct attatatttt atgcagtctg     1260

ctacatgatg gtatccttaa ttttcttcat tggatttttg cttgaagatc gagtagcctg     1320

caatgcatcc atccctgcac aatataaggc ttccacagtg acacaaggat ctcataataa     1380

agcctgtacc atgcttttta tgatactcta tttttttact atggctggca gtgtatggtg     1440

ggtaattctt accatcacat ggtttttagc agctgtgcca aagtggggta gtgaagctat     1500

tgagaagaaa gcattgctgt ttcacgccag tgcatggggc atccccggaa ctctaaccat     1560

catcctttta gcgatgaata aaattgaagg tgacaatatt agtggcgtgt gttttgttgg     1620

cctctacgat gttgatgcat tgagatattt tgttcttgct cccctctgcc tgtatgtggt     1680

agttggggtt tctctcctct tagctggcat tatatcccta aacagagttc gaattgagat     1740

tccattagaa aaggagaacc aagataaatt agtgaagttt atgatccgga tcggtgtttt     1800

cagcattctt tatctcgtac cactcttggt tgtaattgga tgctactttt atgagcaagc     1860

ttaccggggc atctgggaaa caacgtggat acaagaacgc tgcagagaat atcacattcc     1920

atgtccatat caggttactc aaatgagtcg tccagacttg attctctttc tgatgaaata     1980

cctgatggct ctcatagttg gcattccctc tgtattttgg gttggaagca aaaagacatg     2040

ctttgaatgg gccagttttt ttcatggtcg taggaaaaaa gagatagtga atgagagccg     2100

acaggtactc caggaacctg attttgctca gtctctcctg agggatccaa atactcctat     2160

cataagaaag tcaaggggaa cttccactca aggaacatcc acccatgctt cttcaactca     2220

gctggctatg gtggatgatc aaagaagcaa agcaggaagc atccacagca aagtgagcag     2280

ctaccacggc agcctccaca gatcacgtga tggcaggtac acgccctgca gttacagagg     2340

aatggaggag agactacctc atggcagcat gtcacgacta acagatcact ccaggcatag     2400

tagttctcat cggctcaatg aacagtcacg acatagcagc atcagagatc tcagtaataa     2460

tcccatgact catatcacac atggcaccag catgaatcgg gttattgaag aagatggaac     2520

cagtgcttaa tttgtcttgt ctaaggtgga aatcttgtgc tgtttaaaaa gcagatttta     2580

ttctttgcct tttgcatgac tgatagctgt aactcacagt taacatgctt tcagtcaagt     2640

acagattgtg tccactggaa aggtaaatga ttgctttttt atattgcatc aaacttggaa     2700

catcaaggca tccaaaacac taagaattct atcatcacaa aaataattcg tctttctagg     2760

ttatgaagag ataattattt gtctggtaag catttttata aacccactca ttttatattt     2820

agaaaaatcc taaatgtgtg gtgactgctt tgtagtgaac tttcatatac tataaactag     2880

ttgtgagata acattctggt agctcagtta ataaaacaat ttcagaatta aagaaatttt     2940

ctatgcaagg tttacttctc agatgaacag taggactttg tagttttatt tccactaagt     3000

gaaaaaagaa ctgtgttttt aaactgtagg agaatttaat aaatcagcaa gggtatttta     3060

gctaatagaa taaaagtgca acagaagaat ttgattagtc tatgaaaggt tctcttaaaa     3120

ttctatcgaa ataatcttca tgcagagata ttcagggttt ggattagcag tggaataaag     3180

agatgggcat tgtttcccct ataattgtgc tgtttttata acttttgtaa atattacttt     3240

ttctggctgt gtttttataa cttatccata tgcatgatgg aaaaatttta atttgtagcc     3300

atcttttccc atgtaatagt attgattcat agagaactta atgttcaaaa tttgctttgt     3360

ggaggcatgt aataagataa acatcataca ttataaggta accacaatta caaaatggca     3420

aaacattttc tctgtattca ttgttgtatt tttctacagt gagatgtgat cttgccaaag     3480

ccaccagacc ttggcttcca ggccctcctg tagtgagttg attgtctgca cttgccttgc     3540

ccaatagcca gtaggctaca gcttttgccc cacaccctta ttttcagatt ctggatcatt     3600

cttgtttaca actgaaatat atataacctc agtccaaagt ggtgattgat ttgagtattt     3660

gaaaattgtt gtagctaaat gaagcatgat tagtcttagt atgaatatca tttaatcttt     3720

aaaaaatcaa gtaaaaatgt ttatctgata atgtttaaat aatttacaat ataaactgta     3780

aaacttatta ggcatgaaat caatcagaag agaaagaaaa atgctggaac atgcttgatg     3840

tattatgtaa aaagcatatt taaacaaggg tcctcaaccc tgactgcaga taagaatcac     3900

ttgggttact tcagatgcct aacaccttcc tctcatacaa ataagaattg gtagctttct     3960

taaaaaaaaa aaaaaaaaaa aaaagcgctc caggtgattc taatctgcag cctggcttga     4020

aactcactac tttaacttgc ccctgatgat ctgtcggcat catatatcac atgaacatcc     4080

acatggattc tgtctttcgc ttttatatca ttatctaata ttcagttgtt ctgcacctga     4140

tgccaaattc tgggctgtac tcctagagag acttactcag taaggccaaa gtgataggac     4200

tttaaaatct gtagttataa aaataccgca ggtgattctt acggaggtaa tccaagaatc     4260

atactttgaa gaattattct agactctgaa gaggcctggc tctgccttat gctattatag     4320

tttatgacct ttaacaattt aactctccga gcctcagttc ccttgtttgt aaatgaagat     4380

agaagataaa tacgtactct acctacctca caaagctgtc agattaagat caagtgaaaa     4440

aaattatgtg aaagctcttt gaaaactgta aagcattatg aatgataagg gattaggtta     4500

ttgtggattt aagaggtgtg aggactgcta tagtacattc cttgacgtgt gttgaattca     4560

tgtatacttt ctttcttacc ctttaaaaca aactgccaag aaattaggtg ttgaaaaaga     4620

atattctcat caggcagcaa agtcagtttt ctgatagtaa taatttgtct attatgttat     4680

atatttcaaa gtacatgtat gataatatga cttattcttc atgagagata tttgaatatt     4740

tggcccaaaa tgtttttcat ttttctctgt gttcattgcc tttctccttg gagctggagt     4800

taatgctcaa agcaggcagg tctgaattcc ctcataaccg acaattagta aacattttct     4860

ctgaaagcca aacatataac aacttattta tcaataattc atgaagcttt tgtctgagaa     4920

tctctcctgc aaacagcatg agagaactaa aacaaacatt cacaaacaaa aataagttaa     4980

aatagaaggt accagtttgg gctcgaagat gttgtcatcc attgccatct gcattatatt     5040

atcaactgcc aaaatgttaa ttggttttct tttacaagtg ggccaagtat agacagttaa     5100

gtgaacatca ctatgaaaat cttaactttg tgcttctaga tttttagata atcatttgta     5160

ttttctctat taaattgtgg gtatgtatgg gaatactata ttgacttttc agttactttc     5220

agtaagtatc ttaattttgt cccacaaaat ttatgtaata ttaatccatg gttttaaaca     5280

acagtattca gtttgggcag cagttttaag tctaactagc ttaaaccaat ctgaataagt     5340

ctggacagtt ttcctaccat atgtttaact ttgattggca tatgataatg tttagtgttt     5400

tcttttttca gttgacaact gagaaaataa tagttctctc taacatgtta atatattatc     5460

aaaaggtttt caaaaagtac tttgatttca gcaacttttt ttattcaata actagacaaa     5520

agatctaaga taatattaaa ctcaaaacag tttgtttcaa agaacaattg gttaataact     5580

cagctggcac agggattcat acacagtttt tcaataaata tttaaatgaa caattcatgt     5640

cacacaactt gcttttaccc tagtactgag tctcacatca aagaaatttg aaagatctat     5700

aacctatgtg aaatgaagtc tctgctttac cagaataata tgtggcaggt aataaatatg     5760

taaagtacac caaatgaaac atattttgca tagataacag tccatatcac tattataatt     5820

aaagaaatat atgtacagac atgtaccaat ccttttaatt aattttagaa gatgaacagt     5880

gattcttaga agtgagtaat tagactcctt ttagtcttat gctgttagat ctttgtggac     5940

cagctgagta aatgaatctt caaatcaacc tttctttttc tgctgctctt agagcagatt     6000

tataaaaatc ctaagaatgt cttcaaatta gaaaaattta ctacatttta acctacctca     6060

tcagtttctt tgtgataata gctgaaaata actcaaactg tacccatctt agttaggcta     6120

tatctctgtg aaatgaaagg aaccacttaa ttttttttat ataaattagt gaatcatttg     6180

ctggagctta gaaaatatta acataccaaa atttcattat gatgatattt atattgcttt     6240

ttgacatgcc aaaggtacat ttacatatta ccatatttgg atgacttaca tagtctggtg     6300

taatgaaaat tcccctggga ttggaatttt aagactcatg atgtcaactg ggctggtcat     6360

tttatttctc tgagtctttg tttcttcaat gtaaaatgtg gataaggtaa tttttggttt     6420

tagcctccct cactggatat tgtaaggatc aaatgaaata gtatttatta taatgctctg     6480

taacccataa attattctac ttaaaaaaat tttttataga gacagggtct tgctctgtca     6540

cacaggctgg agagcagtgg cataatcata gttcattata accttgaact cctaggctca     6600

agcagtcctc cagcttcagc ctcccaagta gctaagactg taggcatgca ccactacacc     6660

tggctaattt taattttttt ttcttttttt gagacggagt ctggctttgt tgcccaggct     6720

ggagtgcagt ggcacaatct cagctcactg caacctccac ctcccaggtt caagtgattc     6780

ttctgtctca gcctcccgag taactgggac tacaggtgcg tgccaccaca tccagctagt     6840

ttttgtattt ttagtggaga tggagttttg ccatgttggt ctcaaactcc tgacctcaag     6900

tgatctgccc acctcagcct cccaaagtgc taggattaca ggcatgagtc actgcacctg     6960

gcttaatttt aattttttta attttttgta gagatgagtc tcactatgtt gaccaggctg     7020

gtcttgaact cctggcctcc taaagcactg ggattacaag catgagccac catgcctgat     7080

ccataaattg ttctactgat accatttggt tttgttagaa tttggggggg ctatagaaaa     7140

caaggttaca gtcttcatta gtatttcttt ttagcaataa caacaaaata ggcaattaga     7200

ccagtgttca tttggtacag tctttaaatc ggtcatccaa ttaaccttta aaaagtaggt     7260

tatgctctta aattgtattg gttctttaat atgtgttata ccagagtatg cctcaaattt     7320

tatgtagttg aatttgtaga acaaatttgg ggatattcat tttatttttc cttttatatg     7380

aaattgtata agtacattag cttgacttaa attataaaaa aaaatatata tgaagaagaa     7440

tgtagaccct ataatgtttt ttgtctttga ctttttggct tttatgtacc tcattttttc     7500

tgattgagaa aaagttttga aaaagtgatt cacttgttgg ttttcattgt ggcaaaactt     7560

taaattttaa gtcatcacac tatgagaatt gtttgtacac atttataatt tttttaaagt     7620

atgtaaagta aggatttttt ctccattctt cactcacaaa ggatagcatt tttatggaac     7680

ctagatttac aaaggaactt gtgattcttt tcaatgcttt tgtgtcgttt tacagctgat     7740

taagaaaaaa tgtttacatt taattcagct gtatttccta gtagctgtat aatcttacac     7800

attattctta tataattttg acctatttta tatgaaaata attgtattgg catctcttca     7860

taatttaatt ctcttctctc cttcttttgt tccgattaga tgaatttggg aaaggagtag     7920

gaagactagg tatcgcatgc cttccgtctg attgtaatca gtctcctggg ttttttacta     7980

atttaatctt aatcctgtgc ttctttagtc atcaaattga tataggatta caattttctc     8040

tcaggatcca agtcttctaa gaatgaaaat gttgaagtct acccagaacc agccatcctt     8100

gtagacattt ctatttggtt gatttataaa gatttaatat ataaagattt aatatgagtt     8160

aaacatgttt cttattctgt gatctctaat tagaaagtaa aattctgttg ccataaatat     8220

aaaagaaagt tttcacttat attttagtca aacaccaaac cactgcatta cttacttcct     8280

ataagacaca gtagttcaat ctgttgaaag gcattgaagg ataatttcct tcagattact     8340

ttttaaatca tcatctgcct caggaaattc tttcttgaat ttttttgttg gtgtgaaagc     8400

gttgcttata ctttatgctc attttattgg tcactgtcac cagtttttcc cgataaagat     8460

taaaaatgtt ttttaccttg aaataattca gattttgaag attcactgtt tcattatttt     8520

gctaattacc attaactagt aaagttagtt tttaaagttt ttttaaggtt gatattttat     8580

catattcctg gagtaggatg gattacttta ttattattgt agctttaagg ttttttgttg     8640

tataagtcag cttgtttgta tatgctaaat tgcagatatt tctttgtgtt gtgcttattg     8700

gttttttttt ttaacttaga gcttaataat ttctattttc tatcctggag tctaaaatta     8760

aacaaaaaaa tctattttct aaattggcag gattttttta atgattagta aaactgtatt     8820

attttatttt taaaaataca ataggatttt gagtcaggaa acttgacttc tactcttgcc     8880

tctcttttgc agttagctgt gtaactttgg ataaggcatt ttatctcgtg gtgcctccat     8940

ttttctcatt ctctagggaa caagagaatt agtttaggta gcgtctaaaa ttccgcccag     9000

ctctcatttg gttctcattt gaccatttta taatcattat tttggtctca tttttattct     9060

tcttattcat cccatgaact agatcaactt gtattatttt actagatcaa cctgtattat     9120

taacgtcatt tacatgtaaa ttgatgggat tcagatattt tatcaactgt ttttccatta     9180

gtgattttaa gtaattttaa agaaggaaaa ttatattaca gataataaaa atgaaagaaa     9240

gttataaata ttggacatgg cttttttaaa tgggaaagtc ttcttaagca ccaatataag     9300

caccttaaat tgatacatag aaaagaatga cataacgttt tgtggtcttt gttctcttaa     9360

atatgaatat agctagttag cctaaaattt acacaaaatg tattcaagat caaattagtg     9420

aacaaagcaa tggttcgtat ggctaattta aaagcaattc aatttaccaa tattaaaata     9480

attataaaat gtaaaagaaa tttcagagga gttgattgaa aattttttgt tcagtaatta     9540

ttcttaaact gcattcttag gtttattaca taaatatagt tgccagattg ccatgggcaa     9600

gtgaatgtct tcatttgaaa tattattaga gatcaatgtg gcttgttatt tttaattttt     9660

ttctggctat acagaaaatg tttctggaaa aattccttaa ttgtcatctg atataatgta     9720

gagattgagg ccagacgcag tggctcacgc ctgtaatccc agcactttgg gaggccaagg     9780

tgggcagatc acctgaggtc aggagttcga gaccagcctg atgaacatgg caaatcccct     9840

tctgtactaa aaatacaaaa attagccagg cgcagtggct cacgcctgta atcccaacac     9900

tttgggaggc cgaggcgggc ggatcacgag gtcaggagat caagaccgtc ctggctaaca     9960

tggtgagacc ctgtctctac taaaaacaaa aaaattagtt gggcatggtg gcgggcacct    10020

gtagtcccag ccactcggga ggctgaggca ggagaatggc gtgaacccgg gaggcggagc    10080

ttgcagtgag ctgagatcgc accgctgcac tccagcctgg gcaacggagc gagactctat    10140

ctcaaaaaaa aaaaaagaaa aaaaaaaaag tagagattgc attagttcca tatctccgca    10200

gagttctctg gtagattaaa tgttctctgt gcactaggcc aaggaagttc ctgttacctt    10260

tgaaaatcat tgtgtttgct ctgattgtct acattagctc atatcagtct tttgaacact    10320

ggttcaaatc tgggtgttgg gttaggatct gatgagtaga gaatagtgga aagttgatat    10380

aggaaggtat actggtttct ggtgtgattc tttagctaca tttattcctt gtcttatgtc    10440

atttcactgg atcatgtaac tgtcctggct ttcagaaatt atattagatg cccagccttt    10500

ctcattcaga gatgcctgta ttattatgtt atttcgattg cctaccaaaa aaaaaaaaaa    10560

aagaaaaggt ttgtttttag ttctctgcct ctgcaagtct ttgtgatcac atttgttaaa    10620

ttgaatctga gattcaaata tttcatttaa tattttctgg gttttgataa tgggatattc    10680

tgtaagataa agcaagtaat cctagagtga tttactttat gtttagccat ccaccatttt    10740

cctatttctc tactcctccc attctccatt tttaaaagga aattaacaaa tgtcttcctt    10800

tatccctgcc tcagataatt tttccctgaa ctcatcttgt cagcagaaac atttaatgtg    10860

aaataattct gtatttctga gacaagatca acacagtagt tctttacatt gagctgaggt    10920

gaatgtatac ttaaaaatac tctattttct ttttatatga acttaaaatt tttaaaatca    10980

tatatgggac tccccaatgt gaaaatatta gtctggacat tctcttgcca tcaggtgcta    11040

tttctacctt agctgtgagt tagactaaat ccaaatttcg tatcattcat ctttttataa    11100

tatttaactt ccctagaatc accccatttc atgtctttaa ccccaacttc caacaacttt    11160

tctgctttta ttttcaaatg tcaaattgta tttttgtgtt ttattttctc attgaagtgt    11220

aaaagtatca catatatgaa ggaatggctg gtttagacat ttactttggc atagtaaaga    11280

ttgatattga taccacccac catcctttcc tctagcccca gaaagaaaag tttgacaact    11340

caaaaacgat taaattatct tatcttgtta tttaatagaa caatggaagc tgtttcgtca    11400

aaattaaaat actttaccaa aaaaatactt ttttgtattt taatctgata gtgaatttgg    11460

ggattattta tgtaaatgta tcataattaa tagtaattat gagttatttc actctctgta    11520

atttgtgata cccaagattc atatttattt aatgtgaggt gttttttgag gcttttttgt    11580

tttatcttgt tttcttaact ttttacagtg ttgttagatt atcgcggtca tctcggcatg    11640

tggatcgctc ctcctgtaga tcagctgttc tctcttagag tcaggacaag gaggtttttg    11700

ctacatggtc gtagttggat aatacagcat tattctgaac tatctgaaat tgctggtttt    11760

attggtcaaa aatgatcaga tgctagcaat ttcataatag atatattcaa gaaggaacca    11820

aactttaaaa gatcttttag aataggtatg ttaacttctc atcctaaccc tatcaatata    11880

tcagaggctt tatgaaggag actctacaga taaccacaaa tcttatcaag aaaattctcc    11940

ttaaaaaaag ttatccttta ttttgttgtt aaatttccca gtttttaaaa gtgttttatc    12000

aaaatgactt cataattgaa gcaaatacct tttggaagta tatatgttac ataagacttt    12060

cactaaatct gtgcgtaaag cttttataat ctgagatatt gttatgtatt aggtttgtgc    12120

aaacctaata taaaagggtt catctgtaag tatcatttag aggcaaaata atttccccct    12180

cacatctaat gtggactcaa attttggcaa ctggaatgtt atcctcttgg taggcattct    12240

aaattaatga atactgctat gtggtgtagt aaacaaattt gccataaaat gccatttaag    12300

gattttcttt ttacctttat ttcattataa aagtatatga gttgaagatc atataaaaaa    12360

tatgaaactc ctacacagga aatccccaat tttgtgattt aataggttgt aaaaagagtt    12420

gttccaaatt cagactacat ctcatcatat aaataatatt atgaataata agggtaaaag    12480

attagccaac aaaagctaat ctagtacacc ccatagaggt actccaggtg tcttggtttt    12540

ggataaattt ttatagtgga gaaaggttac tttgatctct caataattgc ttggtacact    12600

tcttcctagg caatatgctc atgataccct cttcatgtga cctattcctc aaatgctgca    12660

ttctccaaaa cttccttacc tgccttctat cccctagtca ttcttatcaa tacttccaaa    12720

atataaccta tctcaagtgt tagaaatttg ctttaactaa tttatattaa agtgttagtg    12780

actatagccc ttttatctct cttaaagaga aatctgcatt aaaagcaaac acattgctgt    12840

tagctcaaat taatgtcagt gagtagaatc ttaagcttta aaacaaaagt ggaaataatt    12900

taaattagtg ttgatgggac tattttgagg caagagatac cattaagtga cctagcttgg    12960

aaatctgccc cctttgccca aacccatgtg atgtctgaaa ctactgtata ttttcaatga    13020

ccttgagaaa gggagctagt catttgtatt tatgggcctt atgaagtcag ggcctgctga    13080

tcctgttttt taagttcaag cgcaatgcct gaagcatcct agatctcctt caccctcatt    13140

ctacctgaca gacagctagg tctgtcttcc agctctttct cattgatact acctttacat    13200

atgaatacta tccatgcttg ttaaaaaaaa aaaaagtctt tccccatttt actgttacaa    13260

tttttcaaga gctataaagg tagaaaaagt attccttttc attattctaa aaaatatgtc    13320

atttttaaat agctggcact tagcagttta gttttccaaa ctttattctg aatcaaattg    13380

ctgaggtgat tctaaatgtc taatgttgat ttatcatata aacatctaat tagaaagtgt    13440

ttatgctaaa gacttgtatt ttgtggcatt agttcttcat gtttcttttt tatatgttta    13500

ttaaaattgt tcacttccaa atgagtggaa aagttgctgt tgttgggatg tacagggcaa    13560

gtgcacttgg ttagagcatg aactgggaat ttcacattct ctgatgtgct ttgcactctg    13620

ctcttgtaga tttattttgt ttacagtaga ctgatgtcag tttttgtaaa tgttttttct    13680

tagcacttta actgtgagtg tacaaactga ttttaaatgt agtggttgta tattttggtt    13740

ataaattgga gatttttaat aaaattaaat aattctcttt tctgtcaaaa aaaaaaaaaa    13800

aaaa                                                                 13804


<210>  129
<211>  4311
<212>  DNA
<213>  homo sapiens

<400>  129
gtgctcgggg gttccctggc cctttcggca ggggtaaaac aataagaggg ggcggtggca       60

aagggggcgg gacgtccgtg gtccttgtcg cacgtcgcag cgcctggcgc ccgggaagag      120

gtggttgtga ggcagacgaa ctcgcggctc tccggcttcc gaggcttccg agttgtcgga      180

ggaagggggc ggcgagcaat aagaacccgc cgcacccggt cctcagcgac tcttctgacc      240

tccgcgcgac gtacccgccg ccgccgttgg ctggagcatt tgacattgtg cagcaaagaa      300

atggttatgg agaagcccag tccgctgctt gtagggcggg agtttgtgag gcaatattat      360

actttgctga ataaagctcc ggaatattta cacaggtttt atggcaggaa ttcttcctat      420

gttcatggtg gagtagatgc tagtggaaag ccccaggaag ctgtttatgg ccaaaatgat      480

atacaccaca aagtattatc tctgaacttc agtgaatgtc atactaaaat tcgtcatgtg      540

gatgctcatg caaccttgag tgatggagta gttgtccagg tcatgggttt gctgtctaac      600

agtggacaac cagaaagaaa gtttatgcaa acctttgttc tggctcctga aggatctgtt      660

ccaaataaat tttatgttca caatgatatg tttcgttatg aagatgaagt gtttggtgat      720

tctgagcctg aacttgatga agaatcagaa gatgaagtag aagaggaaca agaagaaaga      780

caaccatctc ctgaacctgt gcaagaaaat gctaacagtg gttactatga agctcaccct      840

gtgactaatg gcatagagga gcctttggaa gaatcctctc atgaacctga acctgagcca      900

gaatctgaaa caaagactga agagctgaaa ccacaagtgg aggagaagaa cttagaagaa      960

ctagaggaga aatctactac tcctcctccg gcagaacctg tttctctgcc acaagaacca     1020

ccaaagccaa gagtcgaagc taaaccagaa gttcaatctc agccacctcg tgtgcgtgaa     1080

caacgaccta gagaacgacc tggttttcct cctagaggac caagaccagg cagaggagat     1140

atggaacaga atgactctga caaccgtaga ataattcgct atccagatag tcatcaactt     1200

tttgttggta acttgccaca tgatattgat gaaaatgagc taaaggaatt cttcatgagt     1260

tttggaaacg ttgtggaact tcgcatcaat accaagggtg ttgggggaaa gcttccaaat     1320

tttggttttg tggtttttga tgactctgaa ccagttcaga gaatcttaat tgcaaaaccg     1380

attatgtttc gaggggaagt acgtttaaat gtggaagaga aaaaaacaag agctgcaaga     1440

gagcgagaaa ccagaggtgg tggtgatgat cgcagggata ttaggcgcaa tgatcgaggt     1500

cccggtggtc cacgtggaat tgtgggtggt ggaatgatgc gtgatcgtga tggaagagga     1560

cctcctccaa ggggtggcat ggcacagaaa cttggctctg gaagaggaac cgggcaaatg     1620

gagggccgct tcacaggaca gcgtcgctga agctccactg ttggcaaagt cttggcagtg     1680

gtacattatt catcgtgttt gcattcttgt taattttttt tttggctttg gaatgtgaca     1740

cagccttttt gatcatttct ttgatgtgaa aagcatcttt ggttatcagt taaattgagg     1800

tggacattat ttccccaatt tcacaacagg attcacattg ttaatttata aatctagact     1860

tggagaatta aggactgaga aatgaccata tcttaaacta tctacgacaa agtgaactta     1920

aaaggacatg cccactgaat tcaggtcctt tgagtaaaaa aaaaatcttc tgctgcacat     1980

tttgtttaag tgttactgtt tctgcctgtt aatgctggga acacaaatag tgcaatttgt     2040

gcaattggag aatcttgcct tttttcttgg ctccccccaa aaatacaaac caacagaaac     2100

ttgttatgca ctcatcaaaa tgtactaatg ggtactctga actcattaac attgacatct     2160

gcaacaggag gcaacaggga aaaaatctca tcttcttttc cagtagaaaa tagtttgtga     2220

aatgatgagg gcattttatc tgcttgctgt gaccagcgtg tgtacacata aaccttaaca     2280

agactacaag tatattccag aaggaaatca ttttagttat gaactaaata ataaaaatta     2340

gaacttcaaa tgcgatggtc ttgactatta gaccagattt agtagctcca tatctaagat     2400

ttttctacct gcccctcttc agtacaggga tggctggctg ctcaacacac tcctcctccc     2460

cttttttcct ttctttaagc tgtgtacagt gaaaattgtc tttactgtat ttttgttctc     2520

tggtaatgta ataagcatga tggtgccttc tattaataca tcattccagt cttgctggta     2580

attttgtaca gtatagtgta tgaattgctg tgctgcaaag ccaaacagct gcaaaatgtt     2640

gaaaaatcat cgaaatgtat aaaaattgca gtatctttaa aatcagtaaa atggactagc     2700

atattattta tcttgttctt cagttaacaa ctttgtgttc tctgtgggag ggagggagtc     2760

ctgtgtgttt gtggggagag ggaaggagga agtcagttat ttgagtaagc ctctagttga     2820

cttttctctt agcctgaatg tggacgttga aacatatcac ttcagggctt ggaaaagtca     2880

gtcaacttga cgtacatttt tagtgacatt ttaaaagcag tcagattcta taaatggcaa     2940

gtaagcctga agtgaggata ctgcaatttt cggagaaaag aacagcagct ctttaagtgt     3000

ttgcattttc tatttggggg gcagggaact gtcattcatt ttgcacaatt cttgaactga     3060

tgtcagcacc cgagtggctc ctgaatttaa gtctgggacg acatctttta tttttacatg     3120

aatctttaaa caattctgtg agcaaagttt gtagctgctg gattattgtc tgtctttata     3180

gcaagttcca gtaaaccaca agtatggcaa agcttatcca attttatgct tggagcagtc     3240

agtacatacc agtttctgat gtttcaggca ggagtggggt aaataagtgt gaccacttaa     3300

agctgctcgt tagcatggaa gacttctcca ttctatcttt gtaaaacaga caagatatgc     3360

acttgacata gtagcaaatt ggttctgaat tatgcaactg tttgctattt agtaaactag     3420

caaatgatgc atgtattttg tttttcatgt actgggcaat atgagtaaaa tctgtccctt     3480

tttccccctt tgaatgaggt cttccatgtt tgagggaaag tcttgcacta ttgcatatat     3540

tttggggaca cagattttca tagtttccat ttttgggggg cttaaggatt tttttttttt     3600

ctgtttgaaa cagttttata ctttctgata tagtacttga aattcttacc agaaaattac     3660

tttggagttt tgaagccttt attaatacta cttttaaaga agcagttgtt ttattgtcaa     3720

tgtttttttt cccccaagca tattttcttg tatttctgtt tccatatata tatatatata     3780

tataatttcc aattcaggat attgccctgc catccatgaa aactgttctg gcaccaaaag     3840

taatgacaaa tgttaagtgt aataatagaa aagtagagca aagagccatt cagcttcagt     3900

ctttacatac catgaataaa acattaaaac atcatatgga gaagtttaca tggtgattgt     3960

tcacctgcag tactgtggag ttttaacatt ttgtcctctt ttcagtgaaa cagagtaaaa     4020

atattcatct accattactg ttatttgctg attttgtttt attttttgat ggtaatattc     4080

tatccttatg acactattgc aaccaaattg gctttaccat cttggcttta gtaggtatag     4140

aagacaatgg attaccatct ttattgctgt aatgtgttaa gcattatatg ctagtagaat     4200

ctagtttaat tgtttcaggt ggaaagtatt ctttgagttt ccatattgaa tgtgtttgga     4260

ctaaacaaac aataaactac tgatgtctgc agcatttatc tatgtcccta a              4311


<210>  130
<211>  4129
<212>  DNA
<213>  homo sapiens

<400>  130
gtgctcgtgg ggagctggcc gagtggaaaa cgtccacatt gacccaaccg cagtgaaggg       60

agagcgcctc cagtggtgtg gtgcgtggag aaatgggaag gagagagttc tgatgagacc      120

ctttttgctc ttcctgctgc atctgagcct gtgatacgct cctctgcaga aaatatggac      180

ttgaaggagc agccaggtaa cactatttcg gctggtcaag aggatttccc atctgtcctg      240

cttgaaactg ctgcttctct tccttctctg tctcctctct cagccgcttc tttcaaagaa      300

catgaatacc ttggtaattt gtcaacagta ttacccactg aaggaacact tcaagaaaat      360

gtcagtgaag cttctaaaga ggtctcagag aaggcaaaaa ctctactcat agatagagat      420

ttaacagagt tttcagaatt agaatactca gaaatgggat catcgttcag tgtctctcca      480

aaagcagaat ctgccgtaat agtagcaaat cctagggaag aaataatcgt gaaaaataaa      540

gatgaagaag agaagttagt tagtaataac atccttcata atcaacaaga gttacctaca      600

gctcttacta aattggttaa agaggatgaa gttgtgtctt cagaaaaagc aaaagacagt      660

tttaatgaaa agagagttgc agtggaagct cctatgaggg aggaatatgc agacttcaaa      720

ccatttgagc gagtatggga agtgaaagat agtaaggaag atagtgatat gttggctgct      780

ggaggtaaaa tcgagagcaa cttggaaagt aaagtggata aaaaatgttt tgcagatagc      840

cttgagcaaa ctaatcacga aaaagatagt gagagtagta atgatgatac ttctttcccc      900

agtacgccag aaggtataaa ggatcgttca ggagcatata tcacatgtgc tccctttaac      960

ccagcagcaa ctgagagcat tgcaacaaac atttttcctt tgttaggaga tcctacttca     1020

gaaaataaga ccgatgaaaa aaaaatagaa gaaaagaagg cccaaatagt aacagagaag     1080

aatactagca ccaaaacatc aaaccctttt cttgtagcag cacaggattc tgagacagat     1140

tatgtcacaa cagataattt aacaaaggtg actgaggaag tcgtggcaaa catgcctgaa     1200

ggcctgactc cagatttagt acaggaagca tgtgaaagtg aattgaatga agttactggt     1260

acaaagattg cttatgaaac aaaaatggac ttggttcaaa catcagaagt tatgcaagag     1320

tcactctatc ctgcagcaca gctttgccca tcatttgaag agtcagaagc tactccttca     1380

ccagttttgc ctgacattgt tatggaagca ccattgaatt ctgcagttcc tagtgctggt     1440

gcttccgtga tacagcccag ctcatcacca ttagaagctt cttcagttaa ttatgaaagc     1500

ataaaacatg agcctgaaaa ccccccacca tatgaagagg ccatgagtgt atcactaaaa     1560

aaagtatcag gaataaagga agaaattaaa gagcctgaaa atattaatgc agctcttcaa     1620

gaaacagaag ctccttatat atctattgca tgtgatttaa ttaaagaaac aaagctttct     1680

gctgaaccag ctccggattt ctctgattat tcagaaatgg caaaagttga acagccagtg     1740

cctgatcatt ctgagctagt tgaagattcc tcacctgatt ctgaaccagt tgacttattt     1800

agtgatgatt caatacctga cgttccacaa aaacaagatg aaactgtgat gcttgtgaaa     1860

gaaagtctca ctgagacttc atttgagtca atgatagaat atgaaaataa ggaaaaactc     1920

agtgctttgc cacctgaggg aggaaagcca tatttggaat cttttaagct cagtttagat     1980

aacacaaaag ataccctgtt acctgatgaa gtttcaacat tgagcaaaaa ggagaaaatt     2040

cctttgcaga tggaggagct cagtactgca gtttattcaa atgatgactt atttatttct     2100

aaggaagcac agataagaga aactgaaacg ttttcagatt catctccaat tgaaattata     2160

gatgagttcc ctacattgat cagttctaaa actgattcat tttctaaatt agccagggaa     2220

tatactgacc tagaagtatc ccacaaaagt gaaattgcta atgccccgga tggagctggg     2280

tcattgcctt gcacagaatt gccccatgac ctttctttga agaacataca acccaaagtt     2340

gaagagaaaa tcagtttctc agatgacttt tctaaaaatg ggtctgctac atcaaaggtg     2400

ctcttattgc ctccagatgt ttctgctttg gccactcaag cagagataga gagcatagtt     2460

aaacccaaag ttcttgtgaa agaagctgag aaaaaacttc cttccgatac agaaaaagag     2520

gacagatcac catctgctat attttcagca gagctgagta aaacttcagt tgttgacctc     2580

ctgtactgga gagacattaa gaagactgga gtggtgtttg gtgccagcct attcctgctg     2640

ctttcattga cagtattcag cattgtgagc gtaacagcct acattgcctt ggccctgctc     2700

tctgtgacca tcagctttag gatatacaag ggtgtgatcc aagctatcca gaaatcagat     2760

gaaggccacc cattcagggc atatctggaa tctgaagttg ctatatctga ggagttggtt     2820

cagaagtaca gtaattctgc tcttggtcat gtgaactgca cgataaagga actcaggcgc     2880

ctcttcttag ttgatgattt agttgattct ctgaagtttg cagtgttgat gtgggtattt     2940

acctatgttg gtgccttgtt taatggtctg acactactga ttttggctct catttcactc     3000

ttcagtgttc ctgttattta tgaacggcat caggcacaga tagatcatta tctaggactt     3060

gcaaataaga atgttaaaga tgctatggct aaaatccaag caaaaatccc tggattgaag     3120

cgcaaagctg aatgaaaacg cccaaaataa ttagtaggag ttcatcttta aaggggatat     3180

tcatttgatt atacggggga gggtcaggga agaacgaacc ttgacgttgc agtgcagttt     3240

cacagatcgt tgttagatct ttatttttag ccatgcactg ttgtgaggaa aaattacctg     3300

tcttgactgc catgtgttca tcatcttaag tattgtaagc tgctatgtat ggatttaaac     3360

cgtaatcata tctttttcct atctatctga ggcactggtg gaataaaaaa cctgtatatt     3420

ttactttgtt gcagatagtc ttgccgcatc ttggcaagtt gcagagatgg tggagctaga     3480

aaaaaaaaaa aaaaagccct tttcagtttg tgcactgtgt atggtccgtg tagattgatg     3540

cagattttct gaaatgaaat gtttgtttag acgagatcat accggtaaag caggaatgac     3600

aaagcttgct tttctggtat gttctaggtg tattgtgact tttactgtta tattaattgc     3660

caatataagt aaatatagat tatatatgta tagtgtttca caaagcttag acctttacct     3720

tccagccacc ccacagtgct tgatatttca gagtcagtca ttggttatac atgtgtagtt     3780

ccaaagcaca taagctagaa gaagaaatat ttctaggagc actaccatct gttttcaaca     3840

tgaaatgcca cacacataga actccaacat caatttcatt gcacagactg actgtagtta     3900

attttgtcac agaatctatg gactgaatct aatgcttcca aaaatgttgt ttgtttgcaa     3960

atatcaaaca ttgttatgca agaaattatt aattacaaaa tgaagattta taccattgtg     4020

gtttaagctg tactgaacta aatctgtgga atgcattgtg aactgtaaaa gcaaagtatc     4080

aataaagctt atagacttaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                 4129


<210>  131
<211>  3154
<212>  DNA
<213>  homo sapiens

<400>  131
gagctcgccg tcgctccgtc atagagttcg ccccacccca tcccctcctt tctggactcg       60

gagctcagtt cacgcagtaa caaatgaagt gcgcgctgcg acacctccca gcccaccgaa      120

ctccgccgcc atttcctcgc ttggcctaac ggttcggcca atcccagcgc gcatcaagaa      180

ggactgaggc tccgccaatc ggaggccgcc gatttcgacc cttcgcctcg gcccggccca      240

atccaggccc cggccccgcc gcccccggcc cgcccccgcg gtgccctctc tcctccctct      300

ttgtgcgtct cgcgccgccg ccgcccgccg cgtgagagga cgggctccgc gcgctccggc      360

agcgcattcg ggtcccctcc ccccgggagg cttgcgaagg agaagccgcc gcagaggaaa      420

agcaggtgcc ggtgcctgtc cccgggggcg ccatggcgac cggagcgaac gccacgccgt      480

tggacttccc aagtaagaag cggaagagga gccgctggaa ccaagacaca atggaacaga      540

agacagtgat tccaggaatg cctacagtta ttccccctgg acttactcga gaacaagaaa      600

gagcttatat agtgcaactg cagatagaag acctgactcg taaactgcgc acaggagacc      660

tgggcatccc ccctaaccct gaggacaggt ccccttcccc tgagcccatc tacaatagcg      720

aggggaagcg gcttaacacc cgagagttcc gcacccgcaa aaagctggaa gaggagcggc      780

acaacctcat cacagagatg gttgcactca atccggattt caagccacct gcagattaca      840

aacctccagc aacacgtgtg agtgataaag tcatgattcc acaagatgag tacccagaaa      900

tcaactttgt ggggctgctc atcgggccca gagggaacac cctgaagaac atagagaagg      960

agtgcaatgc caagattatg atccggggga aagggtctgt gaaagaaggg aaggttgggc     1020

gcaaagatgg ccagatgttg ccaggagaag atgagccact tcatgccctg gttactgcca     1080

atacaatgga gaacgtcaaa aaggcagtgg aacagataag aaacatcctg aagcagggta     1140

tcgagactcc agaggaccag aatgatctac ggaagatgca gcttcgggag ttggctcgct     1200

taaatgggac ccttcgggaa gacgataaca ggatcttaag accctggcag agctcagaga     1260

cccgcagcat taccaacacc acagtgtgta ccaagtgtgg aggggctggc cacattgctt     1320

cagactgtaa attccaaagg cctggtgatc ctcagtcagc tcaggataaa gcacggatgg     1380

ataaagaata tttgtccctc atggctgaac tgggtgaagc acctgtccca gcatctgtgg     1440

gctccacctc tgggcctgcc accacacccc tggccagcgc acctcgtcct gctgctcccg     1500

ccaacaaccc acctccaccg tctctcatgt ctaccaccca gagccgccca ccctggatga     1560

attctggccc ttcagagagt cggccctacc acggcatgca tggaggtggt cctggtgggc     1620

ccggaggtgg cccccacagc ttcccacacc cattacccag cctgacaggt gggcatggtg     1680

gacatcccat gcagcacaac cccaatggac ccccaccccc ttggatgcag ccaccaccac     1740

caccgatgaa ccagggcccc caccctcctg ggcaccatgg ccctcctcca atggatcagt     1800

acctgggaag tacgcctgtg ggctctgggg tctatcgcct gcatcaagga aaaggtatga     1860

tgccgccacc acctatgggc atgatgccgc cgccgccgcc gcctcccagt gggcagcccc     1920

caccccctcc ctctggtcct cttcccccat ggcaacaaca gcagcagcag cctccgccac     1980

cccctccgcc cagcagcagt atggcttcca gtaccccctt gccatggcag caaaatacga     2040

cgactaccac cacgagcgct ggcacagggt ccatcccgcc atggcaacag cagcaggcgg     2100

ctgccgcagc ttctccagga gcccctcaga tgcaaggcaa ccccactatg gtgcccctgc     2160

cccccggggt ccagccgcct ctgccgcctg gggcccctcc ccctccgccg cctccaccgc     2220

ctggttccgc cggcatgatg atccctcccc gcggcggcga tggcccgagc catgagagtg     2280

aggactttcc gcgcccattg gtgacccttc caggcagaca gcctcagcaa cgcccctggt     2340

ggacaggatg gttcggcaaa gcagcctgag ttatttttgt ggacggaatc ggaacacgct     2400

ggctccatat cgtgaaattt ttattaattt ttttcttttt cctttgttac ttctttatct     2460

tttcctttct tcagactccg tccaaggaga tgctctcccc ggtcttctgc tgcaatttag     2520

attcctttcc cttctctcca gttctccttc ccttaccaag gagaggggag caaatggttt     2580

tgggcaaggg ctttggccat tcatgtcaag ctggttgtgg gtttttcaag gtgccatagc     2640

cacccccaaa gatgtttgtt taaagcgtgg ggttttttaa tctctgccac ccttgtcaag     2700

ggagtcttgt aaagttgccg agggtaggtt catctccagg tttcgggatt cccatccgtc     2760

ctggcgatcc tgccagcagt gggtgggcag cctgagctcc ctcgggctcg cctgccagcc     2820

tggagttctt cctgtgctcc ttgatcacct gagctgcctc agattccatt tggtcctctc     2880

cttcctggaa ggcttccttt tatgttttgt tttaatccca aatgtctgaa tgttttgcag     2940

tgtgtagggg tttgagcccc ttgttcattc tccttccttt ttcctcccgc ttccctctcc     3000

atgaagtgat tctgttgaca ataatgtata ctgcgcgttc tcttcactgg tttatctgca     3060

gaaatttctc tgggcttttt tcggtgttag attcaacact gcgctaaagc ggggatgttc     3120

cattgaataa aagagcagtg tggttttctg ggtc                                 3154


<210>  132
<211>  2114
<212>  DNA
<213>  homo sapiens

<400>  132
gagagatgtg ggttacaaag ctgccatcta gaggctagag gctcctttct gcagtgtata       60

taatgcaagt ctgcagccag cagagctcac agttgttgca aagtgctcag cactaaggga      120

gccagcgcac agcacagcca ggaaggcgag cgagcccagc cagcccagcc agcccagcca      180

gcccggaggt catttgattg cccgcctcag aacgatggat ctgcatctct tcgactactc      240

agagccaggg aacttctcgg acatcagctg gccatgcaac agcagcgact gcatcgtggt      300

ggacacggtg atgtgtccca acatgcccaa caaaagcgtc ctgctctaca cgctctcctt      360

catttacatt ttcatcttcg tcatcggcat gattgccaac tccgtggtgg tctgggtgaa      420

tatccaggcc aagaccacag gctatgacac gcactgctac atcttgaacc tggccattgc      480

cgacctgtgg gttgtcctca ccatcccagt ctgggtggtc agtctcgtgc agcacaacca      540

gtggcccatg ggcgagctca cgtgcaaagt cacacacctc atcttctcca tcaacctctt      600

cggcagcatt ttcttcctca cgtgcatgag cgtggaccgc tacctctcca tcacctactt      660

caccaacacc cccagcagca ggaagaagat ggtacgccgt gtcgtctgca tcctggtgtg      720

gctgctggcc ttctgcgtgt ctctgcctga cacctactac ctgaagaccg tcacgtctgc      780

gtccaacaat gagacctact gccggtcctt ctaccccgag cacagcatca aggagtggct      840

gatcggcatg gagctggtct ccgttgtctt gggctttgcc gttcccttct ccattatcgc      900

tgtcttctac ttcctgctgg ccagagccat ctcggcgtcc agtgaccagg agaagcacag      960

cagccggaag atcatcttct cctacgtggt ggtcttcctt gtctgctggc tgccctacca     1020

cgtggcggtg ctgctggaca tcttctccat cctgcactac atccctttca cctgccggct     1080

ggagcacgcc ctcttcacgg ccctgcatgt cacacagtgc ctgtcgctgg tgcactgctg     1140

cgtcaaccct gtcctctaca gcttcatcaa tcgcaactac aggtacgagc tgatgaaggc     1200

cttcatcttc aagtactcgg ccaaaacagg gctcaccaag ctcatcgatg cctccagagt     1260

ctcagagacg gagtactctg ccttggagca gagcaccaaa tgatctgccc tggagaggct     1320

ctgggacggg tttacttgtt tttgaacagg gtgatgggcc ctatggtttt ctagagcaaa     1380

gcaaagtagc ttcgggtctt gatgcttgag tagagtgaag aggggagcac gtgccccctg     1440

catccattct ctctttctct tgatgacgca gctgtcattt ggctgtgcgt gctgacagtt     1500

ttgcaacagg cagagctgtg tcgcacagca gtgctgtgcg tcagagccag ctgaggacag     1560

gcttgcctgg acttctgtaa gataggattt tctgtgtttc ctgaattttt tatatggtga     1620

tttgtattta aattttaaga ctttattttc tcactattgg tgtaccttat aaatgtattt     1680

gaaagttaaa tatattttaa atattgtttg ggaggcatag tgctgacata tattcagagt     1740

gttgtagttt taaggttagc gtgacttcag ttttgactaa ggatgacact aattgttagc     1800

tgttttgaaa ttatatatat ataaatatat ataaatatat aaatatatgc cagtcttggc     1860

tgaaatgttt tatttaccat agttttatat ctgtgtggtg ttttgtaccg gcacgggata     1920

tggaacgaaa actgctttgt aatgcagttt gtgacattaa tagtattgta aagttacatt     1980

ttaaaataaa caaaaaactg ttctggactg caaatctgca cacacaacga acagttgcat     2040

ttcagagagt tctctcaatt tgtaagttat ttttttttaa taaagatttt tgtttcctaa     2100

aaaaaaaaaa aaaa                                                       2114


<210>  133
<211>  2414
<212>  DNA
<213>  homo sapiens

<400>  133
agtccctgcc ctcccctggg gagggtgagt cacgccaaac tgggcggaga gtccgctggc       60

ctcactccta gctcatctgg gcggcggcgg caagtgggga cagggcgggt ggcgcatcac      120

cggcgcggag gcaggaggag cagtctcatt gttccgggag ccgtcaccac agtaggtccc      180

tcggctcagt cggcccagcc cctctcagtc ctccccaacc cccacaaccg cccgcggctc      240

tgagacgcgg ccccggcggc ggcggcagca gctgcagcat catctccacc ctccagccat      300

ggaagacctg gaccagtctc ctctggtctc gtcctcggac agcccacccc ggccgcagcc      360

cgcgttcaag taccagttcg tgagggagcc cgaggacgag gaggaagaag aggaggagga      420

agaggaggac gaggacgaag acctggagga gctggaggtg ctggagagga agcccgccgc      480

cgggctgtcc gcggccccag tgcccaccgc ccctgccgcc ggcgcgcccc tgatggactt      540

cggaaatgac ttcgtgccgc cggcgccccg gggacccctg ccggccgctc cccccgtcgc      600

cccggagcgg cagccgtctt gggacccgag cccggtgtcg tcgaccgtgc ccgcgccatc      660

cccgctgtct gctgccgcag tctcgccctc caagctccct gaggacgacg agcctccggc      720

ccggcctccc cctcctcccc cggccagcgt gagcccccag gcagagcccg tgtggacccc      780

gccagccccg gctcccgccg cgcccccctc caccccggcc gcgcccaagc gcaggggctc      840

ctcgggctca gtggttgttg acctcctgta ctggagagac attaagaaga ctggagtggt      900

gtttggtgcc agcctattcc tgctgctttc attgacagta ttcagcattg tgagcgtaac      960

agcctacatt gccttggccc tgctctctgt gaccatcagc tttaggatat acaagggtgt     1020

gatccaagct atccagaaat cagatgaagg ccacccattc agggcatatc tggaatctga     1080

agttgctata tctgaggagt tggttcagaa gtacagtaat tctgctcttg gtcatgtgaa     1140

ctgcacgata aaggaactca ggcgcctctt cttagttgat gatttagttg attctctgaa     1200

gtttgcagtg ttgatgtggg tatttaccta tgttggtgcc ttgtttaatg gtctgacact     1260

actgattttg gctctcattt cactcttcag tgttcctgtt atttatgaac ggcatcaggc     1320

acagatagat cattatctag gacttgcaaa taagaatgtt aaagatgcta tggctaaaat     1380

ccaagcaaaa atccctggat tgaagcgcaa agctgaatga aaacgcccaa aataattagt     1440

aggagttcat ctttaaaggg gatattcatt tgattatacg ggggagggtc agggaagaac     1500

gaaccttgac gttgcagtgc agtttcacag atcgttgtta gatctttatt tttagccatg     1560

cactgttgtg aggaaaaatt acctgtcttg actgccatgt gttcatcatc ttaagtattg     1620

taagctgcta tgtatggatt taaaccgtaa tcatatcttt ttcctatcta tctgaggcac     1680

tggtggaata aaaaacctgt atattttact ttgttgcaga tagtcttgcc gcatcttggc     1740

aagttgcaga gatggtggag ctagaaaaaa aaaaaaaaaa gcccttttca gtttgtgcac     1800

tgtgtatggt ccgtgtagat tgatgcagat tttctgaaat gaaatgtttg tttagacgag     1860

atcataccgg taaagcagga atgacaaagc ttgcttttct ggtatgttct aggtgtattg     1920

tgacttttac tgttatatta attgccaata taagtaaata tagattatat atgtatagtg     1980

tttcacaaag cttagacctt taccttccag ccaccccaca gtgcttgata tttcagagtc     2040

agtcattggt tatacatgtg tagttccaaa gcacataagc tagaagaaga aatatttcta     2100

ggagcactac catctgtttt caacatgaaa tgccacacac atagaactcc aacatcaatt     2160

tcattgcaca gactgactgt agttaatttt gtcacagaat ctatggactg aatctaatgc     2220

ttccaaaaat gttgtttgtt tgcaaatatc aaacattgtt atgcaagaaa ttattaatta     2280

caaaatgaag atttatacca ttgtggttta agctgtactg aactaaatct gtggaatgca     2340

ttgtgaactg taaaagcaaa gtatcaataa agcttataga cttaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaa                                                       2414


<210>  134
<211>  2321
<212>  DNA
<213>  homo sapiens

<400>  134
ctcttcaatc tcagcacctc caagggtcag cacctcccct ccggctccct ccgctaccgc       60

gggccggaac ttttgtcgat aggaacgggt ttgcacagtt gagtgttgtc ggccggcgtg      120

aaggagacta gggggccatc ctcttccttt cgccgtcgcc gccgcggagc ggagtcgagc      180

cgagctgatt tgatcgagga gcgcggttac cggacgggct gggtctatgg tcgctccgcg      240

ggccgctccg ccggctggtg cttttttatc agggcaagct gtgttccatg gcagggaact      300

tttggcagag ctcccactat ttgcaatgga ttttggataa acaagatctg ttgaaggagc      360

gccaaaagga tttaaagttt ctctcagagg aagaatattg gaagttacaa atatttttta      420

caaatgttat ccaagcatta ggtgaacatc ttaaattaag acaacaagtt attgccactg      480

ctacggtata tttcaagaga ttctatgcca ggtattctct gaaaagtata gatcctgtat      540

taatggctcc tacatgtgtg tttttggcat ccaaagtaga ggaatttgga gtagtttcaa      600

atacaagatt gattgctgct gctacttctg tattaaaaac tagattttca tatgcctttc      660

caaaggaatt tccttatagg atgaatcata tattagaatg tgaattctat ctgttagaac      720

taatggattg ttgcttgata gtgtatcatc cttatagacc tttgctccag tatgtgcagg      780

acatgggcca agaagacatg ttgcttcccc ttgcatggag gatagtgaat gatacctaca      840

gaacggatct ttgcctactg tatcctcctt tcatgatagc tttagcttgc ctacatgtag      900

cctgtgttgt acagcagaaa gatgccaggc aatggtttgc tgagctttct gtggatatgg      960

aaaagatttt ggaaataatc agggttattt taaaactata tgagcagtgg aagaatttcg     1020

atgagagaaa agagatggca accattctta gtaagatgcc aaaaccaaaa ccacctccaa     1080

acagtgaagg agagcagggt ccaaatggaa gtcagaactc tagctacagc caatcttaaa     1140

acattccgaa gaattccata gtggaccact tggaaataaa ccattggaca gatttcagta     1200

atgtcttcag tggaacacaa atgaaaatga atagcttgtt tctgtcaagc atattggaaa     1260

gtgattttat ttttgcaaaa taagtttttc tttaatatga ttctagtaca taattgatta     1320

aaatctcttg attataaatg tttggaaagg ttctaagggg acctacagac agacatacat     1380

agacatttca aaattaatag cttttgatta gtataatatt tcttaatttg gataataaaa     1440

attgtagctt tttattaagc caggaaacat gaagcataat ttgtttaaaa ttctctttgg     1500

tcattgaggg accaaaaaag gacgtaaaat ttacagtcaa tctatgaggg tttttttccc     1560

tccataagtt taactttaaa actgtattta aggaatcaaa tcttacaaaa tcctggaaga     1620

ttttggtaat gatgttgata atttcaggga aattaatcaa gtacctatat tgatttaaaa     1680

gtgtatttta ttcagtagtt tgaggatctt gccatggaag atactagccc agcctagcag     1740

aaaagtgcaa tatgtatagc atactttgac attttaaaca tgatagtcca taaccatttt     1800

gaaatgctgg gcaaactaca tgaagttatt tataattaat tcacagctaa tcaggcattt     1860

tgaaagctta attggattca aaaaccataa tgttggaatt tggtaaaatt ttaatgttga     1920

tttttactgt gaaaaggttt ttataagata tacacaccct agtttaatgt tgtgtcttgg     1980

tgtggattta cagatttact acaggtattc tgaaccagga acacaatcag gtttcaggcc     2040

agtttgatac tggctgtcct taattctaat atgagagtag gacatcatac taaatgttat     2100

gtcagtggga ctgtactgtc tgtggaactt agcaaattaa tcattttctt cagacttgaa     2160

ggagagtgat aaataaaatt tggagtcata ggatattgat gcacaattta aggattaaac     2220

atttttaatc aattgtggat gatggcttat taaatgttga cttcctagta taaaactgca     2280

agaataaaag taacttctcc agctgtaaaa aaaaaaaaaa a                         2321


<210>  135
<211>  2253
<212>  DNA
<213>  homo sapiens

<400>  135
atctaatgag gagcgaggtg cggtgccccg aagcgctcgc ttcccgcggt gcgatctagt       60

cctgcagtag gcggcccggg gccacaccgc ggccgcccaa gccagtgcaa ggcccagggg      120

cctgacatcg ctcccagcgc tcgaggaccg aggcctgctg tggaggacac cgtgctccct      180

cgggacctgc tctggattcc ggcccggacg tccccttgga gctctgcatc tccaacctgg      240

aacccaaccc agaagtctca agtttgacgc atcacgtggc gtgcggatcc actgagggtc      300

cacagagagg ggcgcccatc tcctgcgtct cagttatcct ggtgttggga attctgtgcc      360

ctaaagaatt ccgactcaga tccgaacggg gatctggtgg aatcgagggt gaaagaccag      420

agggacaatg ttctactatc ccaacgtgct tcagcgccac accggctgct ttgccaccat      480

ctggctggcg gcgactcgcg gcagccggtt ggtgaagcgc gaatacctga gggtgaatgt      540

ggtgaaaacc tgcgaggaaa tcctcaatta cgtgctggta cgagtgcaac ccccgcagcc      600

cggcctgccg cggccccgct tctccctcta tctctcagcc caacttcaga tcggtgtgat      660

ccgcgtctat tctcaacaat gccagtacct cgtggaggac atccagcaca tcttggagcg      720

cctccaccgt gcccagctgc agatccgaat agatatggag actgagctac ccagcctgct      780

gcttcctaac cacctggcca tgatggagac cctagaagat gctccagatc ccttttttgg      840

gatgatgtct gtggatccca gacttcctag tcctttcgat atccctcaga ttcgacacct      900

cttagaggct gcaatcccag agagagttga agagatccct cctgaagttc ctacagagcc      960

cagggagcca gagaggattc cggtcactgt gctgccacct gaggccatca cgatcctgga     1020

ggcagagccc atacggatgc tggagattga gggtgaacgg gagctcccag aggtcagccg     1080

ccgagaactg gacctgctga tcgcagagga agaagaagct atcttgttag aaatcccgcg     1140

gctcccacct ccagctcctg cagaggtgga aggaatagga gaggcactgg gtcctgagga     1200

gctgaggctg acaggctggg aacctggggc cctactcatg gaggtgaccc ccccggagga     1260

gctgcgtctg ccagccccac ccagcccaga gaggaggccc ccagtccccc cacctcctcg     1320

ccgccgccgt cgtcgccggt tactgttctg ggacaaggag actcagatct ccccggagaa     1380

attccaggaa caactgcaaa ccagagccca ctgctgggaa tgtcctatgg tgcagccgcc     1440

cgagaggacc atcagaggcc ctgcggagtt gttcagaacc ccaactctct ctggctggct     1500

accccctgaa ctactgggtc tctggaccca ttgtgcccag ccacccccaa aagccctcag     1560

gcgagagctg cctgaggagg cagccgctga ggaggaaagg agaaagattg aagttccaag     1620

tgagattgag gtcccgaggg aggccctgga gcccagtgtt ccccttatgg tgtctttaga     1680

gatctcccta gaggcagctg aagaggagaa gtcccgcatc agcctcatcc caccagaaga     1740

acggtgggcc tggcctgagg tggaggcgcc agaagctcct gcattgcccg tggtgcctga     1800

actccctgag gtgcccatgg agatgccttt ggtgctgccc ccagagctcg agctgctctc     1860

actggaagca gtgcacaggg cagtggcact ggagctgcag gctaacaggg agcccgactt     1920

cagcagcctg gtgtcacctc tcagcccccg caggatggct gcccgggtct tctacctgct     1980

cctggtgctc tcagcgcaac agattcttca cgtgaaacaa gaaaagccat atggtcgcct     2040

cctgatccag ccggggccca gattccactg aggttagagt ccatttacaa agctgccagg     2100

aaaccggcca cttctagtaa accacgtcgt gcctcactgg gtcctgctta cctcatttct     2160

gaatgtgcat ttccagcctt cttgctctca gagctattgt tcaagcagaa aacaagctgc     2220

ttttattaca gtaaaaaaaa aaaaaaaaaa aaa                                  2253


<210>  136
<211>  8761
<212>  DNA
<213>  homo sapiens

<400>  136
gccgaggagg aagaggttga tggcggcggc ggagctccga gagacctcgg ctgggcaggg       60

gccggccgtg gcgggccggg gactgcgcct ctagagccgc gagttctcgg gaattcgccg      120

cagcggacgc gctcggcgaa tttgtgctct tgtgccctcc tccgggcttg ggcccaggcc      180

cggcccctcg cacttgccct taccttttct atcgagtccg catccctctc cagccactgc      240

gacccggcga agagaaaaag gaacttcccc caccccctcg ggtgccgtcg gagcccccca      300

gcccacccct gggtgcggcg cggggacccc gggccgaaga agagatttcc tgaggattct      360

ggttttcctc gcttgtatct ccgaaagaat taaaaatggc cgagaatgtg gtggaaccgg      420

ggccgccttc agccaagcgg cctaaactct catctccggc cctctcggcg tccgccagcg      480

atggcacaga ttttggctct ctatttgact tggagcacga cttaccagat gaattaatca      540

actctacaga attgggacta accaatggtg gtgatattaa tcagcttcag acaagtcttg      600

gcatggtaca agatgcagct tctaaacata aacagctgtc agaattgctg cgatctggta      660

gttcccctaa cctcaatatg ggagttggtg gcccaggtca agtcatggcc agccaggccc      720

aacagagcag tcctggatta ggtttgataa atagcatggt caaaagccca atgacacagg      780

caggcttgac ttctcccaac atggggatgg gcactagtgg accaaatcag ggtcctacgc      840

agtcaacagg tatgatgaac agtccagtaa atcagcctgc catgggaatg aacacaggga      900

tgaatgcggg catgaatcct ggaatgttgg ctgcaggcaa tggacaaggg ataatgccta      960

atcaagtcat gaacggttca attggagcag gccgagggcg acagaatatg cagtacccaa     1020

acccaggcat gggaagtgct ggcaacttac tgactgagcc tcttcagcag ggctctcccc     1080

agatgggagg acaaacagga ttgagaggcc cccagcctct taagatggga atgatgaaca     1140

accccaatcc ttatggttca ccatatactc agaatcctgg acagcagatt ggagccagtg     1200

gccttggtct ccagattcag acaaaaactg tactatcaaa taacttatct ccatttgcta     1260

tggacaaaaa ggcagttcct ggtggaggaa tgcccaacat gggtcaacag ccagccccgc     1320

aggtccagca gccaggcctg gtgactccag ttgcccaagg gatgggttct ggagcacata     1380

cagctgatcc agagaagcgc aagctcatcc agcagcagct tgttctcctt ttgcatgctc     1440

acaagtgcca gcgccgggaa caggccaatg gggaagtgag gcagtgcaac cttccccact     1500

gtcgcacaat gaagaatgtc ctaaaccaca tgacacactg ccagtcaggc aagtcttgcc     1560

aagtggcaca ctgtgcatct tctcgacaaa tcatttcaca ctggaagaat tgtacaagac     1620

atgattgtcc tgtgtgtctc cccctcaaaa atgctggtga taagagaaat caacagccaa     1680

ttttgactgg agcacccgtt ggacttggaa atcctagctc tctaggggtg ggtcaacagt     1740

ctgcccccaa cctaagcact gttagtcaga ttgatcccag ctccatagaa agagcctatg     1800

cagctcttgg actaccctat caagtaaatc agatgccgac acaaccccag gtgcaagcaa     1860

agaaccagca gaatcagcag cctgggcagt ctccccaagg catgcggccc atgagcaaca     1920

tgagtgctag tcctatggga gtaaatggag gtgtaggagt tcaaacgccg agtcttcttt     1980

ctgactcaat gttgcattca gccataaatt ctcaaaaccc aatgatgagt gaaaatgcca     2040

gtgtgccctc cctgggtcct atgccaacag cagctcaacc atccactact ggaattcgga     2100

aacagtggca cgaagatatt actcaggatc ttcgaaatca tcttgttcac aaactcgtcc     2160

aagccatatt tcctacgccg gatcctgctg ctttaaaaga cagacggatg gaaaacctag     2220

ttgcatatgc tcggaaagtt gaaggggaca tgtatgaatc tgcaaacaat cgagcggaat     2280

actaccacct tctagctgag aaaatctata agatccagaa agaactagaa gaaaaacgaa     2340

ggaccagact acagaagcag aacatgctac caaatgctgc aggcatggtt ccagtttcca     2400

tgaatccagg gcctaacatg ggacagccgc aaccaggaat gacttctaat ggccctctac     2460

ctgacccaag tatgatccgt ggcagtgtgc caaaccagat gatgcctcga ataactccac     2520

aatctggttt gaatcaattt ggccagatga gcatggccca gccccctatt gtaccccggc     2580

aaacccctcc tcttcagcac catggacagt tggctcaacc tggagctctc aacccgccta     2640

tgggctatgg gcctcgtatg caacagcctt ccaaccaggg ccagttcctt cctcagactc     2700

agttcccatc acagggaatg aatgtaacaa atatcccttt ggctccgtcc agcggtcaag     2760

ctccagtgtc tcaagcacaa atgtctagtt cttcctgccc ggtgaactct cctataatgc     2820

ctccagggtc tcaggggagc cacattcact gtccccagct tcctcaacca gctcttcatc     2880

agaattcacc ctcgcctgta cctagtcgta cccccacccc tcaccatact cccccaagca     2940

taggggctca gcagccacca gcaacaacaa ttccagcccc tgttcctaca cctcctgcca     3000

tgccacctgg gccacagtcc caggctctac atccccctcc aaggcagaca cctacaccac     3060

caacaacaca acttccccaa caagtgcagc cttcacttcc tgctgcacct tctgctgacc     3120

agccccagca gcagcctcgc tcacagcaga gcacagcagc gtctgttcct accccaacag     3180

caccgctgct tcctccgcag cctgcaactc cactttccca gccagctgta agcattgaag     3240

gacaggtatc aaatcctcca tctactagta gcacagaagt gaattctcag gccattgctg     3300

agaagcagcc ttcccaggaa gtgaagatgg aggccaaaat ggaagtggat caaccagaac     3360

cagcagatac tcagccggag gatatttcag agtctaaagt ggaagactgt aaaatggaat     3420

ctaccgaaac agaagagaga agcactgagt taaaaactga aataaaagag gaggaagacc     3480

agccaagtac ttcagctacc cagtcatctc cggctccagg acagtcaaag aaaaagattt     3540

tcaaaccaga agaactacga caggcactga tgccaacttt ggaggcactt taccgtcagg     3600

atccagaatc ccttcccttt cgtcaacctg tggaccctca gcttttagga atccctgatt     3660

actttgatat tgtgaagagc cccatggatc tttctaccat taagaggaag ttagacactg     3720

gacagtatca ggagccctgg cagtatgtcg atgatatttg gcttatgttc aataatgcct     3780

ggttatataa ccggaaaaca tcacgggtat acaaatactg ctccaagctc tctgaggtct     3840

ttgaacaaga aattgaccca gtgatgcaaa gccttggata ctgttgtggc agaaagttgg     3900

agttctctcc acagacactg tgttgctacg gcaaacagtt gtgcacaata cctcgtgatg     3960

ccacttatta cagttaccag aacaggtatc atttctgtga gaagtgtttc aatgagatcc     4020

aaggggagag cgtttctttg ggggatgacc cttcccagcc tcaaactaca ataaataaag     4080

aacaattttc caagagaaaa aatgacacac tggatcctga actgtttgtt gaatgtacag     4140

agtgcggaag aaagatgcat cagatctgtg tccttcacca tgagatcatc tggcctgctg     4200

gattcgtctg tgatggctgt ttaaagaaaa gtgcacgaac taggaaagaa aataagtttt     4260

ctgctaaaag gttgccatct accagacttg gcacctttct agagaatcgt gtgaatgact     4320

ttctgaggcg acagaatcac cctgagtcag gagaggtcac tgttagagta gttcatgctt     4380

ctgacaaaac cgtggaagta aaaccaggca tgaaagcaag gtttgtggac agtggagaga     4440

tggcagaatc ctttccatac cgaaccaaag ccctctttgc ctttgaagaa attgatggtg     4500

ttgacctgtg cttctttggc atgcatgttc aagagtatgg ctctgactgc cctccaccca     4560

accagaggag agtatacata tcttacctcg atagtgttca tttcttccgt cctaaatgct     4620

tgaggactgc agtctatcat gaaatcctaa ttggatattt agaatatgtc aagaaattag     4680

gttacacaac agggcatatt tgggcatgtc caccaagtga gggagatgat tatatcttcc     4740

attgccatcc tcctgaccag aagataccca agcccaagcg actgcaggaa tggtacaaaa     4800

aaatgcttga caaggctgta tcagagcgta ttgtccatga ctacaaggat atttttaaac     4860

aagctactga agatagatta acaagtgcaa aggaattgcc ttatttcgag ggtgatttct     4920

ggcccaatgt tctggaagaa agcattaagg aactggaaca ggaggaagaa gagagaaaac     4980

gagaggaaaa caccagcaat gaaagcacag atgtgaccaa gggagacagc aaaaatgcta     5040

aaaagaagaa taataagaaa accagcaaaa ataagagcag cctgagtagg ggcaacaaga     5100

agaaacccgg gatgcccaat gtatctaacg acctctcaca gaaactatat gccaccatgg     5160

agaagcataa agaggtcttc tttgtgatcc gcctcattgc tggccctgct gccaactccc     5220

tgcctcccat tgttgatcct gatcctctca tcccctgcga tctgatggat ggtcgggatg     5280

cgtttctcac gctggcaagg gacaagcacc tggagttctc ttcactccga agagcccagt     5340

ggtccaccat gtgcatgctg gtggagctgc acacgcagag ccaggaccgc tttgtctaca     5400

cctgcaatga atgcaagcac catgtggaga cacgctggca ctgtactgtc tgtgaggatt     5460

atgacttgtg tatcacctgc tataacacta aaaaccatga ccacaaaatg gagaaactag     5520

gccttggctt agatgatgag agcaacaacc agcaggctgc agccacccag agcccaggcg     5580

attctcgccg cctgagtatc cagcgctgca tccagtctct ggtccatgct tgccagtgtc     5640

ggaatgccaa ttgctcactg ccatcctgcc agaagatgaa gcgggttgtg cagcatacca     5700

agggttgcaa acggaaaacc aatggcgggt gccccatctg caagcagctc attgccctct     5760

gctgctacca tgccaagcac tgccaggaga acaaatgccc ggtgccgttc tgcctaaaca     5820

tcaagcagaa gctccggcag caacagctgc agcaccgact acagcaggcc caaatgcttc     5880

gcaggaggat ggccagcatg cagcggactg gtgtggttgg gcagcaacag ggcctccctt     5940

cccccactcc tgccactcca acgacaccaa ctggccaaca gccaaccacc ccgcagacgc     6000

cccagcccac ttctcagcct cagcctaccc ctcccaatag catgccaccc tacttgccca     6060

ggactcaagc tgctggccct gtgtcccagg gtaaggcagc aggccaggtg acccctccaa     6120

cccctcctca gactgctcag ccaccccttc cagggccccc acctgcagca gtggaaatgg     6180

caatgcagat tcagagagca gcggagacgc agcgccagat ggcccacgtg caaatttttc     6240

aaaggccaat ccaacaccag atgcccccga tgactcccat ggcccccatg ggtatgaacc     6300

cacctcccat gaccagaggt cccagtgggc atttggagcc agggatggga ccgacaggga     6360

tgcagcaaca gccaccctgg agccaaggag gattgcctca gccccagcaa ctacagtctg     6420

ggatgccaag gccagccatg atgtcagtgg cccagcatgg tcaacctttg aacatggctc     6480

cacaaccagg attgggccag gtaggtatca gcccactcaa accaggcact gtgtctcaac     6540

aagccttaca aaaccttttg cggactctca ggtctcccag ctctcccctg cagcagcaac     6600

aggtgcttag tatccttcac gccaaccccc agctgttggc tgcattcatc aagcagcggg     6660

ctgccaagta tgccaactct aatccacaac ccatccctgg gcagcctggc atgccccagg     6720

ggcagccagg gctacagcca cctaccatgc caggtcagca gggggtccac tccaatccag     6780

ccatgcagaa catgaatcca atgcaggcgg gcgttcagag ggctggcctg ccccagcagc     6840

aaccacagca gcaactccag ccacccatgg gagggatgag cccccaggct cagcagatga     6900

acatgaacca caacaccatg ccttcacaat tccgagacat cttgagacga cagcaaatga     6960

tgcaacagca gcagcaacag ggagcagggc caggaatagg ccctggaatg gccaaccata     7020

accagttcca gcaaccccaa ggagttggct acccaccaca gcagcagcag cggatgcagc     7080

atcacatgca acagatgcaa caaggaaata tgggacagat aggccagctt ccccaggcct     7140

tgggagcaga ggcaggtgcc agtctacagg cctatcagca gcgactcctt cagcaacaga     7200

tggggtcccc tgttcagccc aaccccatga gcccccagca gcatatgctc ccaaatcagg     7260

cccagtcccc acacctacaa ggccagcaga tccctaattc tctctccaat caagtgcgct     7320

ctccccagcc tgtcccttct ccacggccac agtcccagcc cccccactcc agtccttccc     7380

caaggatgca gcctcagcct tctccacacc acgtttcccc acagacaagt tccccacatc     7440

ctggactggt agctgcccag gccaacccca tggaacaagg gcattttgcc agcccggacc     7500

agaattcaat gctttctcag cttgctagca atccaggcat ggcaaacctc catggtgcaa     7560

gcgccacgga cctgggactc agcaccgata actcagactt gaattcaaac ctctcacaga     7620

gtacactaga catacactag agacaccttg tagtattttg ggagcaaaaa aattattttc     7680

tcttaacaag actttttgta ctgaaaacaa tttttttgaa tctttcgtag cctaaaagac     7740

aattttcctt ggaacacata agaactgtgc agtagccgtt tgtggtttaa agcaaacatg     7800

caagatgaac ctgagggatg atagaataca aagaatatat ttttgttatg gctggttacc     7860

accagccttt cttccccttt gtgtgtgtgg ttcaagtgtg cactgggagg aggctgaggc     7920

ctgtgaagcc aaacaatatg ctcctgcctt gcacctccaa taggttttat tatttttttt     7980

aaattaatga acatatgtaa tattaatagt tattatttac tggtgcagat ggttgacatt     8040

tttccctatt ttcctcactt tatggaagag ttaaaacatt tctaaaccag aggacaaaag     8100

gggttaatgt tactttaaaa ttacattcta tatatatata aatatatata aatatatatt     8160

aaaataccag ttttttttct ctgggtgcaa agatgttcat tcttttaaaa aatgtttaaa     8220

aaaaaaaaaa aactgccttt cttcccctca agtcaacttt tgtgctccag aaaattttct     8280

attctgtaag tctgagcgta aaacttcaag tattaaaata atttgtacat gtagagagaa     8340

aaatgacttt ttcaaaaata tacaggggca gctgccaaat tgatgtatta tatattgtgg     8400

tttctgtttc ttgaaagaat ttttttcgtt atttttacat ctaacaaagt aaaaaaatta     8460

aaaagagggt aagaaacgat tccggtggga tgattttaac atgcaaaatg tccctggggg     8520

tttcttcttt gcttgctttc ttcctcctta ccctaccccc cactcacaca cacacacaca     8580

cacacacaca cacacacaca cacacacttt ctataaaact tgaaaatagc aaaaaccctc     8640

aactgttgta aatcatgcaa ttaaagttga ttacttataa atatgaactt tggatcactg     8700

tatagactgt taaatttgat ttcttattac ctattgttaa ataaactgtg tgagacagac     8760

a                                                                     8761


<210>  137
<211>  5961
<212>  DNA
<213>  homo sapiens

<400>  137
agttgccctg tcagtgcagg tggaggcccc ggcggggcaa agtggcagga acctcttaaa       60

gggcgagagc ggcgcggagc cagaacgcgg tcggcccggt ccccgccgca cccagcccag      120

caacatcatg acaacagaga agagtttagt gactgaggcc gaaaattcac agcaccaaca      180

gaaggaagag ggtgaggaag ccataaactc aggccaacaa gaacctcagc aggaggaatc      240

ttgtcaaaca gcagctgaag gagataattg gtgtgaacag aagctgaaag cttctaatgg      300

agacactcct acacatgaag acttgaccaa gaacaaggag cggacatcag aaagcagagg      360

actttcacga ctattctcct cgtttctcaa aaggcccaaa tctcaggtgt ccgaggaaga      420

aggcaaagaa gtagagtcag ataaagaaaa aggtgaagga ggtcagaaag agatagaatt      480

tggaaccagt cttgatgaag agatcatttt aaaggcccca attgcagctc ctgaaccgga      540

actcaaaaca gacccatctt tggatcttca ttcattaagc agtgcagaaa cacagcctgc      600

tcaggaagaa ctcagagaag atccagattt tgaaattaag gaaggagaag gacttgaaga      660

gtgctccaaa atagaagtaa aagaagaaag ccctcaatca aaagcagaaa cagaattaaa      720

agcttcccaa aaaccaatca gaaaacacag gaacatgcac tgcaaggttt ctttgttgga      780

tgacacagtt tatgaatgtg ttgtggagaa acatgctaag ggacaagatt tgcttaaacg      840

agtatgtgag catctcaatc ttttggaaga agactatttt ggtctagcca tttgggataa      900

cgcaacctct aagacatggc tggattccgc caaagaaata aaaaagcagg ttcgtggtgt      960

cccttggaat tttacattta atgtaaagtt ttatccacct gacccagcac agttaacaga     1020

agacataaca agatattatt tatgtcttca gcttcggcag gacatagttg caggacgtct     1080

gccctgttcc tttgcaacct tagcattatt aggttcttac accatccagt ctgaactggg     1140

agactacgac ccagaactcc atggcgtgga ttatgttagt gattttaaac tggccccgaa     1200

tcagaccaag gaacttgaag agaaggtcat ggaactgcat aagtcataca ggtccatgac     1260

tccagctcag gctgacttgg agtttcttga gaatgccaaa aagttgtcta tgtatggagt     1320

tgatcttcat aaagcaaagg acttggaagg agtagatatc atcctaggtg tctgctctag     1380

tggccttctg gtttacaaag ataagctgag aattaaccgc ttcccttggc ccaaagtgct     1440

gaagatttct tataaacgta gtagcttttt catcaagatt cggcctggag agcaagagca     1500

gtatgaaagt accatcggat tcaaacttcc cagttaccga gcagctaaga aattatggaa     1560

agtctgtgta gaacatcaca cgtttttcag attgacatct acagacacca ttcccaaaag     1620

caaatttctt gcgctaggat ccaaatttcg atacagtggc cggactcaag ctcagaccag     1680

gcaagctagt gctctaattg acaggcctgc cccacacttc gagcgtacag caagtaaacg     1740

ggcgtcccgg agcctcgatg gagcagcagc tgtcgattcg gcagaccgaa gtcctcggcc     1800

cacttctgca cctgccatta ctcagggtca ggttgcagaa ggtggcgtcc tagatgcctc     1860

tgctaaaaaa acagtggtcc ctaaagcaca gaaggaaaca gtgaaggctg aagtgaaaaa     1920

ggaagacgag ccacctgagc aagctgagcc agagcccaca gaagcatgga aggtggaaaa     1980

aacccacatc gaggtgacag tacccacctc aaatggtgac caaacacaga agcttgcaga     2040

aaaaactgaa gatctgataa gaatgaggaa gaaaaagaga gaaagactag atggtgaaaa     2100

catttatatc agacatagca atttaatgtt ggaggattta gacaagagtc aagaggagat     2160

caaaaaacat catgccagca tcagtgagct gaaaaagaac ttcatggagt ctgtaccaga     2220

accacggcct agtgaatggg ataaacgctt atccactcac tcacccttcc gaactcttaa     2280

catcaatggg caaatcccca caggagaagg acctcccctg gtgaagacac aaactgtcac     2340

catctcagat aatgccaatg ctgtgaaaag tgaaatccca accaaagacg tccctattgt     2400

ccacactgag accaagacca tcacttatga ggctgcccag actgacgaca acagtggaga     2460

cttggaccca ggagtcttgc tgacagctca aactatcaca tctgagaccc caagcagcac     2520

caccacaact caaattacca agactgtaaa aggtgggatt tcagagacac gtattgaaaa     2580

gagaattgtg atcacaggag atgctgatat tgaccatgat caggtccttg tacaagccat     2640

caaggaggca aaggagcagc acccagacat gtcagtgacc aaggtggtcg tccaccagga     2700

gaccgagatt gctgatgagt gagctcagga actaacctac cccaactctg cccttctccc     2760

atccaagaga aaccagcaaa atgataaaga agctaacctg ccatagtcag acttcagact     2820

ttcaagatta ttctaaatca ccagaaaatt aatttcagtt tctattggga gtttatacca     2880

agagattctt ctagatctca ttgatccttt tgaagagctt tttctatatt aggatatcag     2940

aattgttcaa cttttcactc tatagactgt tttaagagtt ttggggtttt tttaattggg     3000

tggtttgtaa ccccttcagc ctagcctctc tgcccattta tttccaaccc caacagacac     3060

tgacagggtc catggaattc ttcgggaaat cctccaagga ctcttgtcag ctgtgttgga     3120

agccaaagcc agcttagtgg gacttccgcg tctctcccta gtcttatccc ctttggatga     3180

tggcagaaac ttcatgaacc agccctttct cagagccagt gatgtgagtg tatcagaatg     3240

ccagggaggg caccagccct gatccacaga cctcggaaag atgcccctgt tcctttgttg     3300

cgggtggttt tggtaaggca gagccctctg ctgagaatgt agtattgttt ttcccctctc     3360

cctcctgctt tctttttgga gcttctttgg gtcaaagaca tggaagttgc ttcagatatc     3420

tgatactgtg aatgtttgaa catatccgtg gccttcacct ctccagctac ccttttacct     3480

catcagaagc agtggctcag ctaagtgctc cccctagctc ccatctcagg agaccaaatc     3540

tcacagaaaa ataggcactt tgggccaaaa gctctaatgg aacattttta gtggtgattt     3600

ggggaaggaa agttaatgag gtttttaaaa taaggttttc tagttttgag agtgtgcact     3660

tcacacaggg gaatggggtt acttctgtct gatcctgggc ctttctttca tcccaaatga     3720

caaggaatgt ggctcagaga agggtttttc ttttttgacc tttcttctct caacaggaac     3780

ctgcctgagg acacccttct agagcaagga attgactttt aggagccgtt ctccccacaa     3840

gacaccacat gacaaggggt ataagcccca gccctgctca ttcccactca ccagctgagg     3900

tctgtcaggt tttgaaggct tgattttgtg gtgggtttgg ggcttagttt tccttttttt     3960

cattttgatt tttgaaagtg aagatgatgc cctaattcct ggtaaggatt tggggcatag     4020

ttttttgttt ttttgagacg gagtttcgct cttgttgccc aagctggagt gcagtggcgc     4080

gatctcggct cactgcaacc tccgcctcct gggttcaagc agttctcttg cctcagcctc     4140

ccaagtagct gggatgacag gcgcacacca ccacgcccag caaatttttt gtatttttag     4200

tagaaacggg atttcacctt gttaggctgg tctcgaactc ctgacctcag gtgatccacc     4260

caccttggcc tcccaaagtg ctgggattac aggtgtgagc caccacgccc ggccgatttg     4320

gggcattttt atttaacaga acttctctaa ccttccaact gcttcccaca aacacattgg     4380

cctcaaggct ccttagaatc ccagttccag cttcctaaaa tagacagtgg gtatcgggca     4440

gcagtcactg gggctcaagg gcagtgagca agagaaatgt ctaaagctgc ttctcccaac     4500

accgtccaaa gtctccactg cctgagtttt gtttcggctg gtttgaactc atttcgggtg     4560

tgtgcatttt tcttttggta cccatgtgag acatgaacaa caggagggag ggaaagagcc     4620

caggtgggac gtgggacagg cttaggggaa agagcttgtc ctatctcagg aacaaaatta     4680

taggctgtgg gcagagggtc tgaaaggtgg gctttggggt agtgcccaag cctggtcgtg     4740

ttgccaggag tggtgacaag aaatgcagct tacatcaaac gaacatgtag tgcatgccca     4800

ctgcctgatg gccagatggc ctgtaggaag agctaccagg gcttccagac ctgtggaacg     4860

aagaggatgg ggaaaaggca gagggcactg agtgtccctt taaaaactaa cccactgaat     4920

attccgtgtg atctagaaca gtgtggcagc tttcacagca caggaccgtt catcgggggc     4980

ctaaacgttt ccctcagctc tgtcaccaac tcacttctct cggcttcgtt gtctgtaaat     5040

tggatgaaaa gagctctaat gcctttcagg ctcttagaag ccatagattt ggacaagccc     5100

agcaagatgg gtgtccttcc aggcctcttc ccctttcctc catctctggc aacagttctt     5160

ggggtttggc aattgtttgg attttttttc tttctgcagt tgtgtgtatg tgtgtttgtg     5220

tgaagaaaaa cagactctgt ccaggtagaa atggtgagga gggggaagag aattacattt     5280

ccagggtcag aaacttggca acagttttcc tagagtgact cagacacacc acagtaacaa     5340

ctctcgctgc aattttattt taatttgaga aataaagatt tcctccaagc cacatgagga     5400

ctctggcacc cacccacaaa gcaagacctg tatttataag ccgagggctc agggagccta     5460

actgcgggac ccgtcagggc cccgtgaccc atccccgtcc ccaccccccc ctccaccgct     5520

gggcccatca gtgtgtgttg gggggatgct tggcagctgg gggtgaggag acaacaaacc     5580

tcgggaactg gagccagagc tgcggcctga ctgacgcctt ttgatgctca cgggaaattt     5640

ctgcccagga tctcagcccc aggctggttg tttctacaaa tctctctcaa atgtattatt     5700

ttggtgacaa aaatgaagga gctttgtaaa ttttttttaa aattatgaat catatcaagt     5760

agttgtttac atttcttgaa aaaataggaa ctcgggcagc agaatcagat tggcagaatc     5820

tttagactac acaggcaata atcaagtctg ctgttttggc ctttcgtagt agaagtggtt     5880

gtagtgttta gatatctgtt tggtcttgct tcttgtattg catttttttc aataaacaac     5940

aacaaaaaga actctcaaaa a                                               5961


<210>  138
<211>  6159
<212>  DNA
<213>  homo sapiens

<400>  138
atggccatag accggcggcg cgaggcggcg ggcggcgggc ctgggcggca gccggccccg       60

gccgaggaga acggctccct gccgcccggg gacgcggcgg cctcggcgcc cctcggggga      120

cgcgcgggcc ccggcggcgg cgcggagatc cagccgctgc ccccactgca tcctggaggc      180

ggcccgcacc cgagctgctg ctccgcggct gcggccccga gcctcttgtt gctggactat      240

gacgggtcgg tgctgccctt cctcgggggc ctgggcgggg gctatcagaa gaccctcgtg      300

ctgctcacct ggatcccggc gctgttcatc ggcttcagcc agttctcgga ctcgttcctc      360

ctggaccagc ccaacttctg gtgccgcggg gccggcaaag gcaccgagct ggcaggggtc      420

accaccacag gccggggcgg ggacatgggc aactggacca gcctccccac cacccccttc      480

gccactgccc cctgggaggc tgcgggcaac cggagcaaca gcagcggcgc ggacggaggc      540

gacacaccac ccctgccatc ccctccggac aagggggaca acgcctccaa ctgtgactgc      600

cgcgcatggg actacggcat ccgcgccggc ctcgtccaga acgtggtcag caagtgggat      660

cttgtgtgtg ataatgcctg gaaggtccat atcgctaagt tctccttact ggttggatta      720

atctttggct acctaataac tggatgcatt gctgactggg tcggccggcg gcctgtgctg      780

ctgttttcca tcatcttcat tctgatcttt ggactgactg tggcactgtc agtgaatgtg      840

acaatgttca gcacactcag gttctttgaa ggattttgcc tggctggaat cattctcacc      900

ttgtatgctt tacgaataga gctgtgcccc cctggaaaac ggttcatgat tacgatggtg      960

gcgagcttcg tggccatggc gggccagttc ctcatgcctg ggctagccgc cctgtgccgg     1020

gattggcagg tgctgcaggc cctcatcatc tgccccttcc tgctcatgct gctctactgg     1080

tcgatattcc ccgagtccct ccggtggcta atggccaccc agcagtttga gtctgcaaag     1140

aggctgatcc tccacttcac acagaagaat cgcatgaacc ctgagggcga catcaagggt     1200

gtgataccag agctggagaa agagctttcc cggaggccca agaaggtctg catcgtgaag     1260

gtggtgggga cacggaacct gtggaagaac attgtggtcc tgtgtgtgaa ctcgctgacg     1320

gggtacggga tccaccactg ctttgccagg agcatgatgg gccacgaggt gaaggtgccg     1380

ctcctggaga acttctatgc tgactactat accacggcca gcatcgcgct ggtgtcctgc     1440

ctggccatgt gcgtggtggt ccgattcctc gggcgcaggg gagggctgct gctcttcatg     1500

atcctcaccg ccctggcctc actcctgcag ctcggcctcc tcaacctgat tggaaagtac     1560

agccagcacc cagactcagg gatgagtgac agcgtcaagg acaaattttc catcgcgttt     1620

tccatcgtgg gcatgtttgc ctcccatgcg gtggggagcc tcagcgtgtt cttctgtgcg     1680

gagatcaccc cgacggtgat aaggtgtggc gggctggggc tggtgctggc cagcgcgggc     1740

ttcggcatgc tgacggcacc catcatcgag ctgcacaacc agaaaggcta cttcctgcac     1800

cacatcatct ttgcctgctg cacgctcatc tgcatcatct gcatcctcct gctgcccgag     1860

agcagggacc agaacctgcc tgagaacatt tctaacgggg agcactacac gcgccagccg     1920

ctgctgccgc acaagaaggg ggagcagcca ctgctgctca ccaacgccga gctcaaggac     1980

tactcgggcc tccacgatgc cgcagccgcg ggtgacacac tgcccgaggg tgccacggcc     2040

aacggcatga aggccatgta gcccggcctg cggaacccgg ggctccaggg tctggggcag     2100

cttgggcaca ggtttacaga ccagggaccg aacacgcagc caggggtggg aaagctgcct     2160

cagccaagct gagcctctca actggtgtgg ggaaatcctg tctttccaaa agtccaagga     2220

gcgcgggtcg gaggagacaa actctttgga aataaccctt tcaagacttt cttttctgcc     2280

gttaaatgtg tgtatttatt ttggtcattt ttacgagaag cactttattc cctctccctc     2340

tcactgatca caaatggaat cacctccctg ggcagcgaga cgcagttgct ctgggaagat     2400

gccacagtga ccagggccat ggccggtccc tctggggaga tgggacacgg ctcctggcag     2460

cacccaggag ccccccaggc tgcctgcctg cgtgcagagg caggagagga ccgtggagcg     2520

tttccgggac tgcattttag acggagtgaa atgtacatga atttggcttt tgctagagtc     2580

tgtgtatggt tttttaaggt cctttttccc tttctgtttg taaggtaaga gcttctgttc     2640

gtgtgcaggg aaagcagctc acagacgccg ttaaaaccag cttcatcttt ccttcaggat     2700

catccttttg tacttgatgc tggaagctct tggagaaaaa gcttaaacat ttcaccagaa     2760

atcttaattg agcagcagtc atatcgccac agctttgtga gtacacagct aacagatgcg     2820

tcgagacctg agatgtgctc gtttttattc ctcctctccc agattggctc cagcagaaaa     2880

gtccctcgtg cacaggcagc tcttgtgccg gcactacttg aaaacatggc tactttctaa     2940

gctacaaacc attagaaaat aactcaaaaa gatggcagag gcaaatccac agaagggggg     3000

ctgccctcca cacacacacg cccgtcaccc acaccttgag cacacaccat gaagatcacc     3060

agcttggatg gccgtcacct cagacatcac tccagggagc acccgcagga gctgggcccc     3120

ctcacgcctg ccttcctggg ccagcttcct gcttgcagtc actcgcatag cacagaggtg     3180

gggcttcggg cagggagcgg agattcctca taggtgagtc caaatgacct ccagcctctc     3240

gaaggcatca agacaaattg aaagaaagca ataactcacc aaagctcaac gctgcccctg     3300

cctcgacctc catgggtctc ttcgtgttcc tcgtttcacc ccagaaagtg gaggtttcct     3360

cttggcattt tcggaggaaa cttgtaggac acccaaggcg actaagagac agcctccttg     3420

gcaagggcag gcaccacttt gtagcaactt gggcaccagc ttttctggac agcctggctt     3480

cttactggca ttgtccaact catcccttct cgaagcatgt ctttgccatg ggctgtgtcc     3540

ttccagggaa attgtggtct cgggcctggg tgagacaatg aagtgacttc caaccgacag     3600

ttgctagaat tcacagggca gaaaaggggt tgaccttctc cccttctggc tttccacccg     3660

gcctgctgct tgctgtcgcc actcatgtct cctccacatg cggtccacac atcagtaagg     3720

gcctggagat gtgtaaagac acagcaaggg gcaagcagac tcttggccac gtgtttccag     3780

tggctggacc acgccgacac ctgggatctt gagataccca ggaagggagg ctgtctggcc     3840

agcctctccc tgcctccact tgctccacgt ccagctcctc accttccctc ttttttaaag     3900

tcacatttcc atgtttcaac attagtttgc attcaccttt acaaaggcct ttctttagat     3960

ctgtgcagcc tttgcgtgcc aaacttgtga aattcctttt accttttttg gagtacttgc     4020

tataaagcca cctgtcaaca aacccccatt atgtacagaa taggacctat ccagtagcca     4080

ggccagtagg cagttgggga aggtgggaag gatccagcga ggcccctgag cctgcacctg     4140

gacaggtgta cgtctgcacc catcaccctc agcaccaggc caccctgcag tccacttact     4200

gtactgtgtt gtggaaggat atgctaagtg atgaaagttg cgagcagtct cactggtcgt     4260

gtaaactttt tttttttttt ggaaattgaa gctgtagagt gctgcccgaa atctctagga     4320

agttggtggc aagggacagc actcacactc ttctggtcat gatctctgat ctccacctca     4380

aatgacaata aaaaactggt ccaacgaaga cactgctcag cacttcagcc atcaggacta     4440

atccatcgat gactggaaaa gaggctagct ttgaggaaaa cagcctgggc tcttgggagc     4500

agagtccagt gggtgtgagg ctgacttgcc gacggtcggc aggtaatggc tctcagccgg     4560

cgaggcggtc ccacagctct cctcccaggg cagcctgagg aggaggaggc cgggtgcctg     4620

tttggtggca gcttcagcct agggatacct gaagctgttg agcaacacct ttatgaaatg     4680

ttgccagagc agcaacactt ccctgtgggc acagccccgg gaaatccggt accaagtgag     4740

caaggtggca ggacccaccc aagcctgata cgcatctggg cccgccgggc tcagcagggg     4800

aggctgctac ggctgcccac ttcccagcac cgtctgtcac gcttgaaccc ctctgtgctg     4860

ttcccttcct ggctaatagg gagacccttc gcaggcaccc actgtttcaa cttgaccctc     4920

ccaccccctg ctactctcct ccacacaccc ctccgttccg ctagcctacc ctgtcagcct     4980

ttcaataaaa gttatgcaca aatgtgaaca cctgagatgg agctgaacat ttcttcactt     5040

tgttcttttt ctgaagtcaa actcttatca aatgccctaa aattattacc acccaagaga     5100

aacaggaaaa aggttacatg tttttgttta ctgagagtaa gatcacctgc atctggaaga     5160

cgggctggta aattggtttg gctacagaac agaaagaaaa caaaaacaaa cctcgtaagg     5220

gaagtatcac actcagacac caccgcttcc tagagccaaa tgagcaatcc caaactgcaa     5280

gtgccataag tgggcctgtg aggtcacacc gcccggcccg aggtatcgca tgtgcggggg     5340

aggtccacac tacagctgtc ctctcgtcta gaaggcacca cctcgctttc atgtcccgtg     5400

tgttttggaa aagcagtatg gtgtgtcatg tctagcggcg aacacttccc tccctgtcct     5460

tgaggttgta atataaaaac tgtgtttctg tacgtgtggg tgggaattct ctgacggtgc     5520

tcgttcatag cacaagctta cgctgagttc tgaactgtcg ttcacagctg cgtgtctgca     5580

tggtgtcgca tctgttgtac ctttggggaa aatttgtatg taaatgtaca gaaataaaaa     5640

cgttgcccca ttaacagatt tcctctggaa tgtcttccct acctcacctg atggtatcca     5700

ccgaagggca tttcactacc attaatggtg agtaataaaa tcctccgtgt tcattcagac     5760

ctcactgcgt cactactttg aacgcctctg taagctgtgt cttcactcgc cccgaggtgg     5820

gtggagggag gcctctcact ctgcttcgag tcctggtctt aaaggtagtc agaggcagag     5880

gctggattaa acacacactg tttaccaagt gccactctca gaccacctga gagacggggg     5940

ccatcagtaa aattaagagg aatttttttc ccttgttcgt gtatgttctg ctgatccgtg     6000

gcctgaaggt tcctagagac gtcaagaaat gaatatctta cactgtgatt ctgtgaggaa     6060

agactggtaa cccaaaactc tcttctctaa tgtatttttt aacgaaaatg acaatatttc     6120

tttaataaag tatttatacc aaaaaaaaaa aaaaaaaaa                            6159


<210>  139
<211>  3428
<212>  DNA
<213>  homo sapiens

<400>  139
ccaagatctt cctcctaccc tcccctcttt cccttctccc gcggtcggcc ctcgccccct       60

cccccaggcc cagcgcgggc gctcggcgcg tccagacccg cggcgcgatg ccggcagttt      120

aggatccaaa gcttctctgc tccttttgtt ctttccttcc cttttttaaa aaaagagggg      180

ggaaatccca gtggtgggca gcctggcacg cacacagtcg ccctcatacc ccgacaaaag      240

cagatgcact ttgacttctg acagctctac ctcaagcccc ggagaactca gcggcgcttt      300

cctcgcaacc cgagctcggc gagtcgtcgt cttcttcttc tccgttttta tttatttatt      360

tccgttcccg ccgccgttct cgctgacctt cactcctccg cgggctctga gcagaagggt      420

cgcattctct cccgcctgag acttcttttc ctcgccccgg gagctcaggc ggcgccgctc      480

cagcccgggg ccccgggact ccccggctgc acacttcact gagacgcccc cccaggcccc      540

gatcagcctc gtttcctcca ccctactttg atttcctggt gcgagttttg gcttgcacgg      600

ccgagtgtgt gtcctctttt tggagagact ggggagctcg tgccgattgt cttcaggagt      660

catcccctgg gctctacttt gcccctctct ctctctgggc ctcatcagac caaaccaaag      720

accatggttc actgtgccgg ctgcaaaagg cccatcctgg accgctttct cttgaacgtg      780

ctggacaggg cctggcacgt caagtgcgtc cagtgctgtg aatgtaaatg caacctgacc      840

gagaagtgct tctccaggga aggcaaactc tactgcaaga acgacttctt ccggtgtttc      900

ggtaccaaat gcgcaggctg cgctcagggc atctccccta gcgacctggt gcggagagcg      960

cggagcaaag tgtttcacct gaactgcttc acctgcatga tgtgtaacaa gcagctctcc     1020

actggcgagg aactctacat catcgacgag aataagttcg tctgcaaaga ggattaccta     1080

agtaacagca gtgttgccaa agagaacagc cttcactcgg ccaccacggg cagtgacccc     1140

agtttgtctc cggattccca agacccgtcg caggacgacg ccaaggactc ggagagcgcc     1200

aacgtgtcgg acaaggaagc gggtagcaac gagaatgacg accagaacct gggcgccaag     1260

cggcggggac cgcgcaccac catcaaagcc aagcagctgg agacgctgaa ggccgccttc     1320

gctgctacac ccaagcccac ccgccacatc cgcgagcagc tggcgcagga gaccggcctc     1380

aacatgcgcg tcattcaggt ctggttccag aaccggcgct ccaaggagcg gaggatgaag     1440

cagctgagcg ccctgggcgc ccggcgccac gccttcttcc gcagtccgcg ccggatgcgg     1500

ccgctggtgg accgcctgga gccgggcgag ctcatcccca atggtccctt ctccttctac     1560

ggagattacc agagcgagta ctacgggccc gggggcaact acgacttctt cccgcaaggc     1620

cccccgtcct cgcaggccca gacaccagtg gacctaccct tcgtgccgtc atctgggccg     1680

tccgggacgc ccctgggtgg cctggagcac ccgctgccgg gccaccaccc gtcgagcgag     1740

gcgcagcggt ttaccgacat cctggcgcac ccacccgggg actcgcccag ccccgagccc     1800

agcctgcccg ggcctctgca ctccatgtcg gccgaggtct tcggacccag cccgcccttc     1860

tcgtcgctgt cggtcaacgg tggggcgagc tacggaaacc acctgtccca cccccccgaa     1920

atgaacgagg cggccgtgtg gtagcggggt ctcgcacggt ctgcggagtt cgtggttgta     1980

cagaaatgaa cctttattta agaaaaatag aaaaaaaaaa acataaaaag caagtcccca     2040

cccccttcct ccagcctcga gaaccattct ccttctgggg agaccggatg gaaaaggggg     2100

acacgaaata ggatccaaat cggcctcgag gtgggactgg gatccgcgca ctggctgtcg     2160

acgtgcagaa ctggggctcc ccaaaggaaa cgcagacctc tccccaactc ccacctggac     2220

ccggatccgt agacagaccc cgcgggcgtg tgcgcctggc aggcgggcgg cgaaaagacg     2280

tccagggcag ccgcgggtgc gcacagccgt tggcgatgcc aggagccgtg gggagggagg     2340

ccgtgagcac agccgggtga aggaagtgaa gcggcccagg gcgctcccgg gccagccagg     2400

agggttctag ctctgggata tcccttatta gtgttgtctc agagttcaac aacagcgaca     2460

aaaaactctt atagcttcag aaacgccgac ctgccgtgca tcaggtggga ctatatatat     2520

attttttgtc tatctggatt tttggttttt gtttttgcca aaattgcaaa attctaaatg     2580

taaagccctc cgtatcaact cttctacctt cgcaaaacta cacatacaca catacacacg     2640

tacacggaca cactcggtaa gatggtctcc agccagaccg ctcagtaaaa tgacttgaac     2700

atcagctgta caagaaaagt attctacctt cacacacaaa aagttaaaaa aaaaaaaaaa     2760

gactattgaa ctaaaaacag tcaactgttt acgtataatg ttaaattcag gagttcagtg     2820

ttttactaat atatcctgtt ttgaaacctc ttgttcgaaa acaaaatgtt ttgagcaatc     2880

aaccaaaatt gttccttttc ttttcctgta gatgttctga cagatttgca gggctttcgg     2940

ctcactgtgc tagtatgtaa aaaggtgttg tttacacgag gcaaagagaa aacatgctat     3000

tcagacagtt gccaaataga ataattatag cacaaatact gtaaaggtgc ctggcaccag     3060

caacctgaga aagtgttaaa aaaaaaaaaa aaaaagtgtt acaagattta aaaaaaaaca     3120

tctttgctaa tttttttgtc ctgttgaaca ttcatggaat tgttaatatg acttatatag     3180

acccacacag gttttatttt tgtgtcttta aaataaaagt ccaaaatatt taaattttat     3240

ggtcaaatat gcagtcaaca gctgctactt tttctttata tattaaattt ctcatatgtc     3300

ttttattgtt ctaataaacc taagcttgtg tgacctccag tgcatattag accattcact     3360

gtatgaaaga aaacatgttg aataaatttg tgagttttta ataaaaatag aaaatctgat     3420

gtttagat                                                              3428


<210>  140
<211>  2416
<212>  DNA
<213>  homo sapiens

<400>  140
gactgcagag ccggggctgg gctaggcgcg cgcttggaga gcattgcgcg cggctgggcc       60

cgcggccggc ggctcctcct cccactctgc tcctcctctt ttttctcctc ctccacctcc      120

tcctccgcct cctcctcctc ctcttcctcc tcctcttcaa ttctcccggt ggctcgactc      180

ggctcgcagg cttcggagaa acccctactc cagtcgccga ctcagcgccc aagagggtcg      240

ccttgggctg ggggcgcacc ccagggaggg gaggggtcca ggcagctggg ccgccgcgga      300

cacctagcgg cttcagggtg aaccccgacc gcagccgtcg ccgcctcggg cagagtttgc      360

gcccttgctt tgcgccccgg gcgctgaagc cgggcgggcg atgcccgcgg cgtgaaagcg      420

cccgcggcgg gcgccgacct ctgtcctagt ctcctgctcc ccccgccccg cttgtcccgt      480

gcccttgtga ccctggcttt ggcgccgtcg cccaggcgcc ccgcaatgta gctgcccctg      540

cgcctcggcg ggaggcgtcc tgccccgcga gcgcccgggg cccggagccc ggcctggggg      600

ctcagccgag ctcgggcggg gccggggccg cggtggcgat gcaccgggcc cgttagcgcc      660

aggagcgcca ggcagctgag gcggggggca agccctccct cggaggagcc gcgcccccgg      720

ccccgccggt cccgccgcga tgctgttcca cagtctgtcg ggccccgagg tgcacggggt      780

catcgacgag atggaccgca gggccaagag cgaggctccc gccatcagct ccgccatcga      840

ccgcggcgac accgagacga ccatgccgtc catcagcagt gaccgcgccg cgctgtgcgc      900

cggctgcggg ggcaagatct cggaccgcta ctacctgctg gcggtggaca agcagtggca      960

catgcgctgc ctcaagtgct gcgagtgcaa gctcaacctg gagtcggagc tcacctgttt     1020

cagcaaggac ggtagcatct actgcaagga agactactac aggcgcttct ctgtgcagcg     1080

ctgcgcccgc tgccacctgg gcatctcggc ctcggagatg gtgatgcgcg ctcgggactt     1140

ggtttatcac ctcaactgct tcacgtgcac cacgtgtaac aagatgctga ccacgggcga     1200

ccacttcggc atgaaggaca gcctggtcta ctgccgcttg cacttcgagg cgctgctgca     1260

gggcgagtac cccgcacact tcaaccatgc cgacgtggca gcggcggccg ctgcagccgc     1320

ggcggccaag agcgcggggc tgggcgcagc aggggccaac cctctgggtc ttccctacta     1380

caatggcgtg ggcactgtgc agaaggggcg gccgaggaaa cgtaagagcc cgggccccgg     1440

tgcggatctg gcggcctaca acgctgcgct aagctgcaac gaaaacgacg cagagcacct     1500

ggaccgtgac cagccatacc cgagcagcca gaagaccaag cgcatgcgca cgtccttcaa     1560

gcaccaccag cttcggacca tgaagtctta ctttgccatt aaccacaacc ccgacgccaa     1620

ggacttgaag cagctcgcgc aaaagacggg cctcaccaag cgggtcctcc aggtctggtt     1680

ccagaacgcc cgagccaagt tcaggcgcaa cctcttacgg caggaaaaca cgggcgtgga     1740

caagtcgaca gacgcggcgc tgcagacagg gacgccatcg ggcccggcct cggagctctc     1800

caacgcctcg ctcagcccct ccagcacgcc caccaccctg acagacttga ctagccccac     1860

cctgccaact gtgacgtccg tcttaacttc tgtgcctggc aacctggagg gccatgagcc     1920

tcacagcccc tcacaaacga ctcttaccaa ccttttctaa tgactcgcaa cccctcaccc     1980

cacaatttct ttaaaaaaga aattatcttt agttgaattc caagtgtatt ttaaaataga     2040

ggctttgagc aactaactaa ccacatttta ggatctcgcc tggaaacaga ggtaaaaaaa     2100

agaagtgtgc gcccggctaa tgcagcggtg tggaccgagg aacaacttgg aagatctacc     2160

tgcaacacaa catttgtgtc actgtacagt tttgtggact gagcgaggaa aaacaacaaa     2220

taatttaagt tggctagagc ttctgtattt tcaaagactg ccacgtgcct taggaatact     2280

gttttatctc catactttgg atgacttgtt catttttctc tccctctttt tctctgtata     2340

tttatgacca gagcaaaaat gtaaaaaaca aaaaaaacaa caaaaaaagt ttgttacttt     2400

gaatagtcct aaaaag                                                     2416


<210>  141
<211>  2515
<212>  DNA
<213>  homo sapiens

<400>  141
ctacaggcac tgggaacttg caagcagcca gggaacgctg aaaatagcac gtctttttct       60

ttctttgtgt tcaaaactat tttctttctt caccagattt tgttttcctc cccccgctgc      120

agttgtttcc cattagtaac tcgatctctc agagcagtaa gattcgcctt ctacgcctct      180

ttttccctcc gcccgaattg tttgttttct gcacatctcc ttcagggagc cgctgaggct      240

tccccccaac tcttcccagt tctttttgct tcccctcggc cccccaagca gaccgatttc      300

cactccatct gtttcttctc ctcctttctc tccctctttc cctccatcct cgagcgtctc      360

tgcgctccta cagggcagcc ctctctggtc ccttgcctcc ttcactcgga tgagctgaaa      420

gccccgggcg tgtgtatatg gaaatagtgg ggtgccgagc agaagacaac tcgtgtcctt      480

tccgcccccc agccatgctc tttcacggga tctccggagg ccacatccaa ggcatcatgg      540

aggagatgga gcgcagatcc aagactgagg cccgtctggc caaaggcgcc cagctcaacg      600

gccgcgacgc gggcatgccc ccgctcagcc cggagaagcc cgccctgtgc gccggctgcg      660

ggggcaagat ctcggacagg tactatctgc tggctgtgga caaacagtgg catctgagat      720

gcctgaagtg ctgtgaatgt aagctggccc tcgagtccga gctcacctgc tttgccaagg      780

acggtagcat ttactgcaag gaggattact acagaaggtt ctctgtgcag agatgtgccc      840

gctgccacct tggcatttcc gcctcggaga tggtcatgcg cgcccgagac tctgtctacc      900

acctgagctg cttcacctgc tccacttgca acaagactct gaccacgggc gaccatttcg      960

gcatgaagga cagcctggtg tactgccgcg cccacttcga gaccctcttg caaggagagt     1020

atccaccgca gctgagctac acggagctgg cggccaagag cggcggcctg gccctgcctt     1080

acttcaacgg tacgggcacc gtgcagaaag ggcggccccg gaagcggaag agcccagcgc     1140

tgggagtgga catcgtcaat tacaactcag gttgtaatga gaatgaggca gaccacttgg     1200

accgggacca gcagccttat ccaccctcgc agaagaccaa gcgcatgcga acctctttca     1260

agcatcacca gctccggacc atgaaatcct actttgccat caaccacaac ccggatgcca     1320

aggacctcaa gcagcttgcc cagaaaacag gtctgaccaa aagagttttg caggtttggt     1380

tccaaaacgc acgagccaaa ttcagaagga accttttgcg gcaggagaat gggggtgttg     1440

ataaagctga cggcacgtcg cttccggccc cgccctcagc agacagcgga gctctcactc     1500

cacccggcac tgcgaccact ttaacagacc tgaccaatcc cactatcact gtagtgacat     1560

ccgtgacctc taacatggac agccacgaat ccggaagccc ctcacaaact accttaacaa     1620

accttttcta acattggttt ttttttttta gtttttaaat tcttcctctt ctttttatta     1680

ttattctaat tattattatt ttattattta caagactttt tttttcttct aacccacaag     1740

atatttgggg aataaaaata acagcttggt gtgtagcatc tgcagccact tggcaaatga     1800

gtttacagta ttgtctcctt taagtgaata tattttgtct acaaagtgta tttggattta     1860

aaaaaattaa ttaggtcttt cagttggtaa ggagagtttt tgaataattc taataagtgc     1920

ctcttaaaat tgtatgttac ttatttccag aatctcgaag aaaaaagaaa aaagagtggt     1980

attattatgg gcaaataatc atattcccac ttaaatgatt aggttaataa agaaccagat     2040

aattaattag ttacttttta aatcttgcaa ttgtatgtgt gattatggag ttttgaaaac     2100

gttacatttt ttaaatctta aaactgaaaa cttgttttta gtatttctat ttcttacctg     2160

aactgttaat tcaagtgagg aatatgatga aataaaagca ttaactacag acattttaaa     2220

tagtaatgat taattaggtg agaaatctat tacaggaatg tgacttttcc ttctcttagg     2280

ggtgtacaac tctaaaaact ttttacttgg ttatttgttt ttcaacattt gaaaaatact     2340

taagctccct atgtatccat gaaaattccg cattgatttt gacattccat acttttaacc     2400

tcctaaagct aaaaacaata gctcggaaac cattctttct agttactttt tttcccaggg     2460

aaaatggaaa taagcaaaat ataatgtttt aagaagtaaa aaaatcaata taatt          2515


<210>  142
<211>  1021
<212>  DNA
<213>  homo sapiens

<400>  142
ccgctgttat acgtcacttc cacggctcag cgtcagggag gagagagaat gtcttttcga       60

ggcggaggtc gtggaggctt taatcgaggt ggtggaggtg gcggcttcaa ccgaggtggc      120

agcagcaacc acttccgagg tggaggcggc ggtggaggcg gcggcaattt cagaggcggc      180

ggcaggggag gatttggacg agggggtggc cgcggaggct ttaacaaagg ccaagaccaa      240

ggacctccag aacgtgtagt cttattagga gagttcctgc atccctgtga agatgacata      300

gtttgtaaat gtaccacaga tgaaaataag gtgccttatt tcaatgctcc tgtttactta      360

gaaaacaaag aacaaattgg aaaagtggat gaaatatttg gacaactcag agatttttat      420

ttttcagtta agttgtcaga aaacatgaag gcttcatcct ttaaaaaact acagaagttt      480

tatatagacc catataagct gctgccactg cagaggtttt tacctcgacc tccaggtgag      540

aaaggacctc caagaggtgg tggcagggga ggccgaggag gaggaagagg aggaggtggc      600

agaggtggtg gcagaggcgg tggttttaga ggtggaagag gaggtggagg tgggggcttc      660

agaggaggaa gaggtggtgg tttcagaggg agaggacatt aagtgaaaca gttgacagac      720

atcaccagtt gacttctgca ttaacctgca tgatctgttt ctactatgga ttggaaactt      780

gtttcttgaa caagtcttga agatcttggt cattttatga caatggatct aaaatgtcag      840

catcatgcaa agtgcaacgg aatagtgaat tttgctctaa aagagcatga acaagtcttt      900

ctaatgtttt gtacagtgcc tggcactctg tgggtgctca ataaatggat aggagttttc      960

atttgaagca tatttgaatt tttaaaataa agtgttttat tcccttaaaa aaaaaaaaaa     1020

a                                                                     1021


<210>  143
<211>  1280
<212>  DNA
<213>  homo sapiens

<400>  143
ccgctgttat acgtcacttc cacggctcag cgtcaggcaa gttggcctct ctgttgtaaa       60

ttagtggtta aggttatcta ttattgccac ttttccagcg ctaaaggctg ttttggaacc      120

agtgttgctt gttccgcggg tgattggctt ttttttttgg caaaccagtt attcaagttt      180

ctggtcttta aaaaactctg tggcggtacg gtaaccgagg aggttccagc gcggcggaag      240

taccccgcgg gtgggtgtgt gcgcaaggcc agggccagag gggcacgtgg cgccgggagg      300

agagagaatg tcttttcgag gcggaggtcg tggaggcttt aatcgaggtg gtggaggtgg      360

cggcttcaac cgaggtggca gcagcaacca cttccgaggt ggaggcggcg gtggaggcgg      420

cggcaatttc agaggcggcg gcaggggagg atttggacga gggggtggcc gcggaggctt      480

taacaaaggc caagaccaag gacctccaga acgtgtagtc ttattaggag agttcctgca      540

tccctgtgaa gatgacatag tttgtaaatg taccacagat gaaaataagg tgccttattt      600

caatgctcct gtttacttag aaaacaaaga acaaattgga aaagtggatg aaatatttgg      660

acaactcaga gatttttatt tttcagttaa gttgtcagaa aacatgaagg cttcatcctt      720

taaaaaacta cagaagtttt atatagaccc atataagctg ctgccactgc agaggttttt      780

acctcgacct ccaggtgaga aaggacctcc aagaggtggt ggcaggggag gccgaggagg      840

aggaagagga ggaggtggca gaggtggtgg cagaggcggt ggttttagag gtggaagagg      900

aggtggaggt gggggcttca gaggaggaag aggtggtggt ttcagaggga gaggacatta      960

agtgaaacag ttgacagaca tcaccagttg acttctgcat taacctgcat gatctgtttc     1020

tactatggat tggaaacttg tttcttgaac aagtcttgaa gatcttggtc attttatgac     1080

aatggatcta aaatgtcagc atcatgcaaa gtgcaacgga atagtgaatt ttgctctaaa     1140

agagcatgaa caagtctttc taatgttttg tacagtgcct ggcactctgt gggtgctcaa     1200

taaatggata ggagttttca tttgaagcat atttgaattt ttaaaataaa gtgttttatt     1260

cccttaaaaa aaaaaaaaaa                                                 1280


<210>  144
<211>  1021
<212>  DNA
<213>  homo sapiens

<400>  144
ccgctgttat acgtcacttc cacggctcag cgtcagggag gagagagaat gtcttttcga       60

ggcggaggtc gtggaggctt taatcgaggt ggtggaggtg gcggcttcaa ccgaggtggc      120

agcagcaacc acttccgagg tggaggcggc ggtggaggcg gcggcaattt cagaggcggc      180

ggcaggggag gatttggacg agggggtggc cgcggaggct ttaacaaagg ccaagaccaa      240

ggacctccag aacgtgtagt cttattagga gagttcctgc atccctgtga agatgacata      300

gtttgtaaat gtaccacaga tgaaaataag gtgccttatt tcaatgctcc tgtttactta      360

gaaaacaaag aacaaattgg aaaagtggat gaaatatttg gacaactcag agatttttat      420

ttttcagtta agttgtcaga aaacatgaag gcttcatcct ttaaaaaact acagaagttt      480

tatatagacc catataagct gctgccactg cagaggtttt tacctcgacc tccaggtgag      540

aaaggacctc caagaggtgg tggcagggga ggccgaggag gaggaagagg aggaggtggc      600

agaggtggtg gcagaggcgg tggttttaga ggtggaagag gaggtggagg tgggggcttc      660

agaggaggaa gaggtggtgg tttcagaggg agaggacatt aagtgaaaca gttgacagac      720

atcaccagtt gacttctgca ttaacctgca tgatctgttt ctactatgga ttggaaactt      780

gtttcttgaa caagtcttga agatcttggt cattttatga caatggatct aaaatgtcag      840

catcatgcaa agtgcaacgg aatagtgaat tttgctctaa aagagcatga acaagtcttt      900

ctaatgtttt gtacagtgcc tggcactctg tgggtgctca ataaatggat aggagttttc      960

atttgaagca tatttgaatt tttaaaataa agtgttttat tcccttaaaa aaaaaaaaaa     1020

a                                                                     1021


<210>  145
<211>  2844
<212>  DNA
<213>  homo sapiens

<400>  145
agcagccggc acggggacag ccggccgcac aacggatctg caggcgcgga gcaaaatgca       60

cccgccgcgc cgcgcggtcc tgcagccccg ccacggcccc gcggcccgca cccccccggg      120

gcgacagtga gcctctcccg ccaccaccgg gggccgagcg gagggctctc gggtgggaga      180

gcgggaccag atctcgacag ctgttcattt ccaggaagcc accgcagcca gagcgaaagg      240

ggaccttctg ccaccagcgg ggcatcagcc agcggcgcgc atggatttat gaagacactc      300

atgcaagaag tgggcaggac ttggacaaac ttttccaccg gctccgcgtc cgccgctccc      360

cgcgcctcgt ctcctttccc ctcctctccc ggcggccgcc gctgcccgcg atggtggccg      420

cgctgctggg cggcggcggc gaggcccgcg gggggacagt gccgggcgcc tggctgtgcc      480

tgatggcgct gctgcagctg ctgggctcgg cgccgcgggg atcggggctg gcgcacggcc      540

gccgcctcat ctgctggcag gcgctgctgc agtgccaggg ggagccggag tgcagctacg      600

cctacaacca gtacgccgag gcgtgcgcgc cggtgctggc gcagcacggc gggggcgacg      660

cgcccggggc cgccgccgcc gctttcccgg cctcggccgc ctctttctcg tcgcgctggc      720

gctgcccgag tcactgcatc tcggccctca ttcagctcaa ccacacgcgc cgcgggcccg      780

ccctggagga ctgtgactgc gcgcaggacg agaactgcaa gtccaccaag cgcgccattg      840

agccgtgcct gccccggacg agcggcggcg gcgcgggcgg ccccggcgcg ggcggggtca      900

tgggctgcac cgaggcccgg cggcgctgcg accgcgacag ccgctgcaac ctggcgctga      960

gccgctacct gacctactgc ggcaaagtct tcaacgggct gcgctgcacg gacgaatgcc     1020

gcaccgtcat tgaggacatg ctggctatgc ccaaggcggc gctgctcaac gactgcgtgt     1080

gcgacggcct cgagcggccc atctgcgagt cggtcaagga gaacatggcc cgcctgtgct     1140

tcggcgccga gctgggcaac ggccccggca gcagcggctc ggacgggggc ctggacgact     1200

actacgatga ggactacgat gacgagcagc gcaccggggg cgcgggtggt gagcagccgc     1260

tggacgacga cgacggcgtc ccgcacccac cgcgcccggg cagcggcgct gctgcatcgg     1320

gcggccgcgg ggacctgccc tatgggcctg ggcgcaggag cagcggcggc ggcggccgct     1380

tggcgccccg gggcgcctgg accccactcg cctccatctt gctgctgctg cttgggccgc     1440

tcttttagcc ctcgcgcccc ccgccgttgg ctgcgggaga gcccgcgtcc cactcccgtg     1500

ctcgcctcga ccccgcgccg ggcacctgtg gcttgggaca gatagaaggg atggttgggg     1560

atacttccca aaactttttc caagtcaact tggtgtagcc ggttccccgg ccacgactct     1620

gggcacttcc cctgaagctc ctctccggag cttgacttct tggacctcct cccccgcccc     1680

aattccaagc tccagaaact cccaactcgt ctgccgtcca gaaagctagc tgcagtgttc     1740

aggacgtccg ggaggaagca agcatgtggg ggacagaaca gtagtcctgg actcgaaagg     1800

gaaggtgctg accagtgggg ccttagcaat ttgaagggtt gggaaggagg aattatattt     1860

gcaaaggggc tgtctattag catatttcct ttgagggggc aaaaaaaagt gccagtatcg     1920

acttttacag attgtggcca gtgaggatat tataatccta tgtaaacaga aaagtcccac     1980

ttaccgattc attctttcac tgtttgtatc tgcgcccaga attctcagtg acgtgggggt     2040

gagggtgggt ggcgattgcc ttagagggaa cccctaaatt ggttttggat aagtttgagc     2100

ccttgacctt aatttcattg ctaccactct gatctcttag cacatttctt aggattaagg     2160

gtccaaaaat gctgatctaa ggggttgcca tggtgttgaa caatgcaact ttttatttaa     2220

aaaagctctg cactgccatg tatgaaagtc tctttatgat gtttgttttt ttgtcatttt     2280

tgttctttac atcaagaaat tttatgttta aatatgcgga gaatgtatat tgcctctgct     2340

cctatcaggg ttgctaaacc ctggtacatc gtatataaaa tgtattaaaa ctggggtttg     2400

ttaccagttg ctgtactttg tatatagaat ttttataaat tgtatgcttc agaaataatt     2460

tatttttaaa aagaaattaa aagttttaaa ctcacatcca tattacacct ttcccccctg     2520

aaatgtatag aatccatttg tcatcaggaa tcaaaaccca cagtccattg tgaagtgtgc     2580

tatatttaga acagtcttaa aatgtacagt gtattttata gaattgaagt taacattctt     2640

attttcaaga gaatttatgg acgttgtaga aatgtacaaa tgcatttcca aactgcctta     2700

aacgttgtat ttttatagac atgtttttta aaaatcctaa gtttttaaat aactatggat     2760

ttgtgtattt tttttggtta tttgttttat taaaacatgt acatcagtaa agagttttaa     2820

acaatgaaaa aaaaaaaaaa aaaa                                            2844


<210>  146
<211>  8865
<212>  DNA
<213>  homo sapiens

<400>  146
gtcactttca tgaattcaaa ggcaatttac cagtgatttc tgggtgctgg ggctgatatt       60

ttttgtgcat atttaagaat gtcttccaag caagccacct ctccatttgc ctgtgcagct      120

gatggagagg atgcaatgac ccaggattta acctcaaggg aaaaggaaga gggcagtgat      180

caacatgtgg cctcccatct gcctctgcac cccataatgc acaacaaacc tcactctgag      240

gagctaccaa cacttgtcag taccattcaa caagatgctg actgggacag cgttctgtca      300

tctcagcaaa gaatggaatc agagaataat aagttatgtt ccctatattc cttccgaaat      360

acctctacct caccacataa gcctgacgaa gggagtcggg accgtgagat aatgaccagt      420

gttacttttg gaaccccaga gcgccgcaaa gggagtcttg ccgatgtggt ggacacactg      480

aaacagaaga agcttgagga aatgactcgg actgaacaag aggattcctc ctgcatggaa      540

aaactacttt caaaagattg gaaggaaaaa atggaaagac taaataccag tgaacttctt      600

ggagaaatta aaggtacacc tgagagcctg gcagaaaaag aacggcagct ctccaccatg      660

attacccagc tgatcagttt acgggagcag ctactggcag cgcatgatga acagaaaaaa      720

ctggcagcgt cacaaattga gaaacaacgg cagcaaatgg accttgctcg ccaacagcaa      780

gaacagattg cgagacaaca gcagcaactt ctgcaacagc agcacaaaat taatctcctg      840

cagcaacaga tccaggttca gggtcacatg cctccgctca tgatcccaat ttttccacat      900

gaccagcgga ctctggcagc agctgctgct gcccaacagg gattcctctt cccccctgga      960

ataacataca aaccaggtga taactacccc gtacagttca ttccatcaac aatggcagct     1020

gctgctgctt ctggactcag ccctttacag ctccagaagg gtcatgtctc ccacccacaa     1080

attaaccaaa ggctaaaggg cctaagtgac cgttttggca ggaatttgga cacctttgaa     1140

catggtggtg gccactctta caaccacaaa cagattgagc agctctatgc cgctcagctg     1200

gccagcatgc aggtgtcacc tggagcaaag atgccatcaa ctccacagcc accaaacaca     1260

gcagggacgg tctcacctac tgggataaaa aatgaaaaga gagggaccag ccctgtaact     1320

caagttaagg atgaagcagc agcacagcct ctgaatctct catcccgacc caagacagca     1380

gagcctgtaa agtccccaac gtctcccacc cagaacctct tcccagccag caaaaccagc     1440

cctgtcaatc tgccaaacaa aagcagcatc cctagcccca ttggaggaag cctgggaaga     1500

ggatcctctt tagatatcct atctagtctc aactcccctg ccctttttgg ggatcaggat     1560

acagtgatga aagccattca ggaggcgcgg aagatgcgag agcagatcca gcgggagcaa     1620

cagcagcaac agccacatgg tgttgacggg aaactgtcct ccataaataa tatggggctg     1680

aacagctgca ggaatgaaaa ggaaagaacg cgctttgaga atttggggcc ccagttaacg     1740

ggaaagtcaa atgaagatgg aaaactgggc ccaggtgtca tcgaccttac tcggccagaa     1800

gatgcagagg gaggtgccac tgtggctgaa gcacgagtct acagggacgc ccgcggccgt     1860

gccagcagcg agccacacat taagcgacca atgaatgcat tcatggtttg ggcaaaggat     1920

gagaggagaa aaatccttca ggccttcccc gacatgcata actccaacat tagcaaaatc     1980

ttaggatctc gctggaaatc aatgtccaac caggagaagc aaccttatta tgaagagcag     2040

gcccggctaa gcaagatcca cttagagaag tacccaaact ataaatacaa accccgaccg     2100

aaacgcacct gcattgttga tggcaaaaag cttcggattg gggagtataa gcaactgatg     2160

aggtctcgga gacaggagat gaggcagttc tttactgtgg ggcaacagcc tcagattcca     2220

atcaccacag gaacaggtgt tgtgtatcct ggtgctatca ctatggcaac taccacacca     2280

tcgcctcaga tgacatctga ctgctctagc acctcggcca gcccggagcc cagcctcccg     2340

gtcatccaga gcacttatgg tatgaagaca gatggcggaa gcctagctgg aaatgaaatg     2400

atcaatggag aggatgaaat ggaaatgtat gatgactatg aagatgaccc caaatcagac     2460

tatagcagtg aaaatgaagc cccggaggct gtcagtgcca actgaggagt ttttgtttgc     2520

tgaattaaag tactctgaca tttcaccccc ctccccaaca aagagttatt aaagagcccg     2580

catgcatttg tggctccaca attacatcag cagaatggtc ttaattgttt cgtaaagtgt     2640

gagacagatt aagttttccc tgatttttca tgaacttgag ttttttgttg ttattgttat     2700

tgttgttgtt gttgtttttt taatttaggt gaagacatat taaatatgag acaccaggac     2760

ttgaaactta tctcaacccg tagatgtctt acaagtctta tatttttgtc ttactttttt     2820

tttcttttgg atgttgataa aggtttaagt tactgtttta gatggggtta aacattctca     2880

ctcaggtatg ctgtgccggc ctacaggttg tgaatgtgtt tttattctga attattttag     2940

aaaacaactg aggatttcat attgtgaaac agaacaagtc cacggcgtgt gcagctgcat     3000

gtagagcata ttcaaaaggc ctcggaattc caattttcca tttgtagagt taaactttga     3060

atgtgccaaa ctttttcgta acttttgaat cttaatattt tgaaagtctt aaaggagaca     3120

ctgcaaagtc ttagacaatc tttggcatct taaaataaaa tagcaaacca acattttttt     3180

ttccagaaaa tggtaaggta ctcaggaatc tggagacaag atattgtaag gaatgaacaa     3240

ggttgccaca gtgcatggac ccaattgtgt ttgcctgttg acgtgccatc agtgcgtgat     3300

gtggtatgac atacacacac cagagcaacc gccacaccag atatcgacag agtggtcttc     3360

tctgcctgag accacctctc actacatcca ttatcccttt gcctttaacc ctgacattca     3420

gtcttaacac attttatctt aaataattta ttcattccag aatgtcaagg gtccacttgc     3480

tatttatttt ttttcaattg ttggtggcat taatttaata attcttgttt ttcaccttcc     3540

ttccccgaag aacttttccg tccttttcac ctccttctcc tgtgtacata gtgattttat     3600

gtccccagaa cgcctggaag catttctgaa accaagatat tattaaaaac ctattattgt     3660

ttttaatcat gagtatgtat ctggctgcag ggctgtgtat tgggatatag gtatatagtc     3720

ttacacttaa acaggtatgc ccctgaggtt cactgtgacc tcaagtcttt tgccagaatt     3780

ttcccctaat tcagttcaca agtggtaggg tctgcatcag tggcatttcc ccctgaattc     3840

cattcagcag caaggttcaa cagtggtgac tgccaggcag gagagtcctg cggccaaacc     3900

tgaagcccaa ggctcgtggg ccatgcagga atctcagtga agctgtcatg ggctggcacc     3960

tttacactga gttgccttgt cccagctggc acatctaggg agttcattgc aaaatcccca     4020

ggatgcaaaa agccacatga cagcctcaga gcaaagatgg tggcaaatag tcatgataca     4080

tctagagaat gaaagaaaac tgtaagggag gagaaggagg ggaatacatt ccctatatgg     4140

gatgttccta ctgttaactc tggggaacag atagctccgg gggcagcaga tgagttcctc     4200

tggctgactc tatctgtagc cacatgggga cctgcctacg tgtgaacaaa atgaactgca     4260

cttatcacac aaggatttct ttgaagacat gctactgggg tgggaagcag tgaggtttta     4320

ttccccatct cctaactaca gggagctctg ccatgtcatt ttggccttcc tgaaactagg     4380

acaggttgtc tatcgggggg cttcccccag agaggtttag tgggagaatg tcagtgaatg     4440

ggatagttca cctcatggga caacccagaa tctgatcacc aggacatagg aatggcccca     4500

tcagatttct tgagccattt tgtcacttgg aagaaaatag tgtacctttg tatttattta     4560

agagtgctca aggcctaata gcaataaaca ggtctagcca agaaattaca agctattctg     4620

ttagctggga gtgctctcta taagctgatt aaggtactga taggaactct ttgttattca     4680

tgttggttgg ggattagaaa tttgtttttg tacatttatt tcaaatgagg aggaggtcat     4740

tttttctctc aaaaaatgag tatttattat tgtcttactg atttctttga ttatatacct     4800

ctcctcctca gttcactctt gttttttttc tttctctttg gcttttgctt ttgctctctc     4860

tcacttcttt cttattttgt tgcattggta gagtgttgta tggctagcat tgtattgtat     4920

gtaattaatt ttgcacaaaa gcaaacattt agcatagtag gttaattttg tttgttttta     4980

tgaccatgcc aaaataatat tctgggctgg tggagaacaa aggactgttc tttaggactg     5040

aaacttgatt ttgctcatag taagtaaaaa aaaacaaaaa acacacacac tcacagatgt     5100

tgtttcgtaa gtgttataag cactggatat aaatggtatt ttttatcact tctgactaat     5160

gtgaaactgt tgtacgaaaa ctacatgaac aaaagtcatc tgtttcgact cgtgtgggct     5220

tgcctcacag ttgccggatt tgagtcattt ttatgtcttg ttatttcatt tatttatgca     5280

aaatacatgt gtgtatgaac actttgtttt agctccagct ctgcctcagt actggggttc     5340

atttactttt agccatgttc ttaaaaatga aaggctattc aggaatgatc tgattgtaaa     5400

cgtctttttc attggatcaa acagtaatgc tgtatttgaa tctaaatttt gtgtataagc     5460

agtttattta ttagccaagt ttggctctaa atatccatgg aaattaagaa tgacaatcat     5520

agggatcaat tcattttatt ttcagtgggg cttaaacaaa gtttatatga ctttaccatc     5580

tcattttaga tttttctaat tgtgtaaata taacatagaa atagaattta tttttggttc     5640

atgaatactt agtgagatat aagttatgta tttccttttt gttctctatc catagatgtt     5700

ggtccaaact gaaagttgat gagtcactgt gcctctcggg gtagtgagtt atcagctaca     5760

gtgagagagc agtgtttggc ctgcagctgg gacagcaaaa cgtttcacca gggttctcat     5820

gcagttcaga acccactgtc cacagatcca gacatttccc ttttttctta cagaaagttg     5880

atgattggac atactaaatt tccactacag ttaggagaca gtcagtttgc tttgggagtc     5940

tacataaatc ttctaagata gttctgtgac catttaatag caagaagcat gaatgccact     6000

acaaaggcaa aaatccacct ctgagatcgg ccgttaataa acgtcccgtc atgtcagttt     6060

agattcaaga atgttaagca actttgtttt tgcggtgctc cctatttcat agtatcttca     6120

aatcaaaaat aaaaattatc tccattttgt taaagaactt acagggtcag ggttctcctt     6180

gtcacttaga attgggacac tgccaggcaa tcctctccca aaaaaaaaaa aaaaaaaaaa     6240

tagccatatg gaatggaagg aaaaggagaa aagaaggaag aaaggaaaaa agtaggaagg     6300

gagagagaaa aaaaaggtcg ctttgcggat acgagccgct aggctgacaa cttttctatt     6360

tcattggcag atatgaagca gtgtcttttc cagtaaggta cggaagcttt gttgttttca     6420

tgtgtaccca gctcagcctt ttagaagcac ctcggtttgc ttcattaggt atttgatact     6480

ctccagcctt gtcctcaggc ctgatttgat ttgccagggt cctgacacca aagcccaggc     6540

caagttctaa attcaggtgt gggctcacag tgctattgag cttgtcgaat tctggcctcc     6600

cctgaacatt agccccacgg gagcctgagg gtgtttgaaa agggcgtgat cactctaggg     6660

ctgaaattaa aggctgcttt cttttccttc tgaagccagg ctgcttcttc ggagtacacc     6720

ctcctgagcc aggagcacaa gcactagcag aaagcaggga ttgtttcagg aaagcccatt     6780

taccctcagt aggaaggcag cctggtcact tgaacagcac agctgaggct gcttctctca     6840

atttactcat tttgcaaaga attgacctct accaactcat tagggagagg aaaaagaatc     6900

acttagtaat tttaaatcat atgagaagtc ctgtaccaag tgccaacaac tgcaaagaaa     6960

tgcagctaga ggaatgtatt gaaattacta ctgggtcttc ctttttaatg agaaaatgac     7020

aaaaatggtt gctgtagccc tgcctgattt tgtacacgtt tgtctaagaa ttgagttggc     7080

acttaagctc acttctcaaa gtataataat attgtatgac ctcatttgtc ctttcacaaa     7140

agcacttgca tcatttcctt aagtcatctg ctccctgaca tgttttcttc cctaataaac     7200

aacttctgtc tgttattcct gccaatgatg ttctgtttct gatgccatat cctattgagc     7260

gtgcccctgt actaatatca ttgaaaatat tgatatgcaa acacatttcc ttttcatccc     7320

cattctatct ttccctttgg ggacagattg ctttccaaaa gctcatgaac aaatatttgg     7380

aatgctggta cctttggggc agaggtaagg gtgggcgggg tgggggcaga aaggtaatgc     7440

ttaatgcaga taactcttct aatcagtgtc catggcaata tgaacgcttg aagaaaactc     7500

agtgacatat cttgctcagt agtttcttat tcctgaagaa ccacaagcat aaagtgaggc     7560

ctcagtgctg gtgctcttgg agtatgggga atgtgcaaat atttaactgt tttgtatgct     7620

gcacattgca ggtctgctca tgtgcattct ccctttgtct tcctttgtca tatgtgtttt     7680

tgcttttttg aaagtgcagt ctttattgta ccctcctcca gcttgtagca aattagaatg     7740

cttagcattt atgttcattc attattgtat ttgccatgta aaatttttat taccttagac     7800

aagcttataa gctgttacta cataacttat cttactgtaa ctcttttatt tcccccgacg     7860

ttgtaatttg tttgtgatgt atattgtgaa attgtattct atgttaattt aatcagcaca     7920

attcactgac atgctggact gacatgctgg ctgctgtttc aaagtgtaaa gtttgtgtag     7980

ggctgttggg acaactgcaa ctctgttgtc aaggtactgt gctttggttc ctatagcaac     8040

actgggtgtg gcccttgaat tgctaagggc atttaataca tcctggagca aattttaact     8100

gcagattttc tttgtagaaa ttctatgtat aatgcaggta cctacttggc ccatggctgg     8160

taactatttg ggcaattaga aaaaaagaaa aaaacataaa aactagtgtc tattgctgct     8220

ttgaatatgt ttgaaagtct gaaaatgtaa atagtttatc aaaaaaaaat cttgtacagt     8280

ccagtgtaaa gtttttaaat gaccttaagg gttgccatca catctttctc acactctcct     8340

cttgataata ataataataa aaagtttgct aaggattaaa gaaatgggaa aaataaaaaa     8400

aatctcttca aatttacagg aatgaatcat tgttcttagc tttgttgcat acacaaactt     8460

cttggatttt gttgtgcagt attgacgtga gataaagctc aacattgaat aatctttcag     8520

tggtactttt caaagtcttc ccctcctctg cctcataatt aagggaaaag acaaaattga     8580

aagacacact gtctttatct atcctggtgt atgttggcac cttagctact tttttttttt     8640

cctttttgca caaggtgctt tcctgatatg ttcaacatgc catctttggg tgataatgta     8700

tatgccgtga tggggctcag gccccttagg ggagtgtcta taagaactgc ctatttatgc     8760

tcatttacct caagactgtc ctctctaccc taatctagtt gtcatcactc catcttttgt     8820

actgctgttg acacttacaa attaaagata aattttgttt tatga                     8865


<210>  147
<211>  8979
<212>  DNA
<213>  homo sapiens

<400>  147
agttgttagg agagaccatt ggggatagga aagatgaaag gtcatggtga gcttcaagga       60

catgaaaggt tgttgtctca tgtaacaata gtagattgtt ttttttccta atatttctag      120

ccagccccta agtcaggtga tggaacaaat acctacagtt tagtcaggtg aaacaggagt      180

gggtggagga aggaaagaag aaaaatggga agaatgtctt ccaagcaagc cacctctcca      240

tttgcctgtg cagctgatgg agaggatgca atgacccagg atttaacctc aagggaaaag      300

gaagagggca gtgatcaaca tgtggcctcc catctgcctc tgcaccccat aatgcacaac      360

aaacctcact ctgaggagct accaacactt gtcagtacca ttcaacaaga tgctgactgg      420

gacagcgttc tgtcatctca gcaaagaatg gaatcagaga ataataagtt atgttcccta      480

tattccttcc gaaatacctc tacctcacca cataagcctg acgaagggag tcgggaccgt      540

gagataatga ccagtgttac ttttggaacc ccagagcgcc gcaaagggag tcttgccgat      600

gtggtggaca cactgaaaca gaagaagctt gaggaaatga ctcggactga acaagaggat      660

tcctcctgca tggaaaaact actttcaaaa gattggaagg aaaaaatgga aagactaaat      720

accagtgaac ttcttggaga aattaaaggt acacctgaga gcctggcaga aaaagaacgg      780

cagctctcca ccatgattac ccagctgatc agtttacggg agcagctact ggcagcgcat      840

gatgaacaga aaaaactggc agcgtcacaa attgagaaac aacggcagca aatggacctt      900

gctcgccaac agcaagaaca gattgcgaga caacagcagc aacttctgca acagcagcac      960

aaaattaatc tcctgcagca acagatccag gttcagggtc acatgcctcc gctcatgatc     1020

ccaatttttc cacatgacca gcggactctg gcagcagctg ctgctgccca acagggattc     1080

ctcttccccc ctggaataac atacaaacca ggtgataact accccgtaca gttcattcca     1140

tcaacaatgg cagctgctgc tgcttctgga ctcagccctt tacagctcca gcagctctat     1200

gccgctcagc tggccagcat gcaggtgtca cctggagcaa agatgccatc aactccacag     1260

ccaccaaaca cagcagggac ggtctcacct actgggataa aaaatgaaaa gagagggacc     1320

agccctgtaa ctcaagttaa ggatgaagca gcagcacagc ctctgaatct ctcatcccga     1380

cccaagacag cagagcctgt aaagtcccca acgtctccca cccagaacct cttcccagcc     1440

agcaaaacca gccctgtcaa tctgccaaac aaaagcagca tccctagccc cattggagga     1500

agcctgggaa gaggatcctc tttaggtaaa tggaaaagtc aacaccagga agagacttac     1560

gaattagata tcctatctag tctcaactcc cctgcccttt ttggggatca ggatacagtg     1620

atgaaagcca ttcaggaggc gcggaagatg cgagagcaga tccagcggga gcaacagcag     1680

caacagccac atggtgttga cgggaaactg tcctccataa ataatatggg gctgaacagc     1740

tgcaggaatg aaaaggaaag aacgcgcttt gagaatttgg ggccccagtt aacgggaaag     1800

tcaaatgaag atggaaaact gggcccaggt gtcatcgacc ttactcggcc agaagatgca     1860

gagggaagta aagcaatgaa tggctctgca gctaaactac agcagtatta ttgttggcca     1920

acaggaggtg ccactgtggc tgaagcacga gtctacaggg acgcccgcgg ccgtgccagc     1980

agcgagccac acattaagcg accaatgaat gcattcatgg tttgggcaaa ggatgagagg     2040

agaaaaatcc ttcaggcctt ccccgacatg cataactcca acattagcaa aatcttagga     2100

tctcgctgga aatcaatgtc caaccaggag aagcaacctt attatgaaga gcaggcccgg     2160

ctaagcaaga tccacttaga gaagtaccca aactataaat acaaaccccg accgaaacgc     2220

acctgcattg ttgatggcaa aaagcttcgg attggggagt ataagcaact gatgaggtct     2280

cggagacagg agatgaggca gttctttact gtggggcaac agcctcagat tccaatcacc     2340

acaggaacag gtgttgtgta tcctggtgct atcactatgg caactaccac accatcgcct     2400

cagatgacat ctgactgctc tagcacctcg gccagcccgg agcccagcct cccggtcatc     2460

cagagcactt atggtatgaa gacagatggc ggaagcctag ctggaaatga aatgatcaat     2520

ggagaggatg aaatggaaat gtatgatgac tatgaagatg accccaaatc agactatagc     2580

agtgaaaatg aagccccgga ggctgtcagt gccaactgag gagtttttgt ttgctgaatt     2640

aaagtactct gacatttcac ccccctcccc aacaaagagt tattaaagag cccgcatgca     2700

tttgtggctc cacaattaca tcagcagaat ggtcttaatt gtttcgtaaa gtgtgagaca     2760

gattaagttt tccctgattt ttcatgaact tgagtttttt gttgttattg ttattgttgt     2820

tgttgttgtt tttttaattt aggtgaagac atattaaata tgagacacca ggacttgaaa     2880

cttatctcaa cccgtagatg tcttacaagt cttatatttt tgtcttactt tttttttctt     2940

ttggatgttg ataaaggttt aagttactgt tttagatggg gttaaacatt ctcactcagg     3000

tatgctgtgc cggcctacag gttgtgaatg tgtttttatt ctgaattatt ttagaaaaca     3060

actgaggatt tcatattgtg aaacagaaca agtccacggc gtgtgcagct gcatgtagag     3120

catattcaaa aggcctcgga attccaattt tccatttgta gagttaaact ttgaatgtgc     3180

caaacttttt cgtaactttt gaatcttaat attttgaaag tcttaaagga gacactgcaa     3240

agtcttagac aatctttggc atcttaaaat aaaatagcaa accaacattt ttttttccag     3300

aaaatggtaa ggtactcagg aatctggaga caagatattg taaggaatga acaaggttgc     3360

cacagtgcat ggacccaatt gtgtttgcct gttgacgtgc catcagtgcg tgatgtggta     3420

tgacatacac acaccagagc aaccgccaca ccagatatcg acagagtggt cttctctgcc     3480

tgagaccacc tctcactaca tccattatcc ctttgccttt aaccctgaca ttcagtctta     3540

acacatttta tcttaaataa tttattcatt ccagaatgtc aagggtccac ttgctattta     3600

ttttttttca attgttggtg gcattaattt aataattctt gtttttcacc ttccttcccc     3660

gaagaacttt tccgtccttt tcacctcctt ctcctgtgta catagtgatt ttatgtcccc     3720

agaacgcctg gaagcatttc tgaaaccaag atattattaa aaacctatta ttgtttttaa     3780

tcatgagtat gtatctggct gcagggctgt gtattgggat ataggtatat agtcttacac     3840

ttaaacaggt atgcccctga ggttcactgt gacctcaagt cttttgccag aattttcccc     3900

taattcagtt cacaagtggt agggtctgca tcagtggcat ttccccctga attccattca     3960

gcagcaaggt tcaacagtgg tgactgccag gcaggagagt cctgcggcca aacctgaagc     4020

ccaaggctcg tgggccatgc aggaatctca gtgaagctgt catgggctgg cacctttaca     4080

ctgagttgcc ttgtcccagc tggcacatct agggagttca ttgcaaaatc cccaggatgc     4140

aaaaagccac atgacagcct cagagcaaag atggtggcaa atagtcatga tacatctaga     4200

gaatgaaaga aaactgtaag ggaggagaag gaggggaata cattccctat atgggatgtt     4260

cctactgtta actctgggga acagatagct ccgggggcag cagatgagtt cctctggctg     4320

actctatctg tagccacatg gggacctgcc tacgtgtgaa caaaatgaac tgcacttatc     4380

acacaaggat ttctttgaag acatgctact ggggtgggaa gcagtgaggt tttattcccc     4440

atctcctaac tacagggagc tctgccatgt cattttggcc ttcctgaaac taggacaggt     4500

tgtctatcgg ggggcttccc ccagagaggt ttagtgggag aatgtcagtg aatgggatag     4560

ttcacctcat gggacaaccc agaatctgat caccaggaca taggaatggc cccatcagat     4620

ttcttgagcc attttgtcac ttggaagaaa atagtgtacc tttgtattta tttaagagtg     4680

ctcaaggcct aatagcaata aacaggtcta gccaagaaat tacaagctat tctgttagct     4740

gggagtgctc tctataagct gattaaggta ctgataggaa ctctttgtta ttcatgttgg     4800

ttggggatta gaaatttgtt tttgtacatt tatttcaaat gaggaggagg tcattttttc     4860

tctcaaaaaa tgagtattta ttattgtctt actgatttct ttgattatat acctctcctc     4920

ctcagttcac tcttgttttt tttctttctc tttggctttt gcttttgctc tctctcactt     4980

ctttcttatt ttgttgcatt ggtagagtgt tgtatggcta gcattgtatt gtatgtaatt     5040

aattttgcac aaaagcaaac atttagcata gtaggttaat tttgtttgtt tttatgacca     5100

tgccaaaata atattctggg ctggtggaga acaaaggact gttctttagg actgaaactt     5160

gattttgctc atagtaagta aaaaaaaaca aaaaacacac acactcacag atgttgtttc     5220

gtaagtgtta taagcactgg atataaatgg tattttttat cacttctgac taatgtgaaa     5280

ctgttgtacg aaaactacat gaacaaaagt catctgtttc gactcgtgtg ggcttgcctc     5340

acagttgccg gatttgagtc atttttatgt cttgttattt catttattta tgcaaaatac     5400

atgtgtgtat gaacactttg ttttagctcc agctctgcct cagtactggg gttcatttac     5460

ttttagccat gttcttaaaa atgaaaggct attcaggaat gatctgattg taaacgtctt     5520

tttcattgga tcaaacagta atgctgtatt tgaatctaaa ttttgtgtat aagcagttta     5580

tttattagcc aagtttggct ctaaatatcc atggaaatta agaatgacaa tcatagggat     5640

caattcattt tattttcagt ggggcttaaa caaagtttat atgactttac catctcattt     5700

tagatttttc taattgtgta aatataacat agaaatagaa tttatttttg gttcatgaat     5760

acttagtgag atataagtta tgtatttcct ttttgttctc tatccataga tgttggtcca     5820

aactgaaagt tgatgagtca ctgtgcctct cggggtagtg agttatcagc tacagtgaga     5880

gagcagtgtt tggcctgcag ctgggacagc aaaacgtttc accagggttc tcatgcagtt     5940

cagaacccac tgtccacaga tccagacatt tccctttttt cttacagaaa gttgatgatt     6000

ggacatacta aatttccact acagttagga gacagtcagt ttgctttggg agtctacata     6060

aatcttctaa gatagttctg tgaccattta atagcaagaa gcatgaatgc cactacaaag     6120

gcaaaaatcc acctctgaga tcggccgtta ataaacgtcc cgtcatgtca gtttagattc     6180

aagaatgtta agcaactttg tttttgcggt gctccctatt tcatagtatc ttcaaatcaa     6240

aaataaaaat tatctccatt ttgttaaaga acttacaggg tcagggttct ccttgtcact     6300

tagaattggg acactgccag gcaatcctct cccaaaaaaa aaaaaaaaaa aaaatagcca     6360

tatggaatgg aaggaaaagg agaaaagaag gaagaaagga aaaaagtagg aagggagaga     6420

gaaaaaaaag gtcgctttgc ggatacgagc cgctaggctg acaacttttc tatttcattg     6480

gcagatatga agcagtgtct tttccagtaa ggtacggaag ctttgttgtt ttcatgtgta     6540

cccagctcag ccttttagaa gcacctcggt ttgcttcatt aggtatttga tactctccag     6600

ccttgtcctc aggcctgatt tgatttgcca gggtcctgac accaaagccc aggccaagtt     6660

ctaaattcag gtgtgggctc acagtgctat tgagcttgtc gaattctggc ctcccctgaa     6720

cattagcccc acgggagcct gagggtgttt gaaaagggcg tgatcactct agggctgaaa     6780

ttaaaggctg ctttcttttc cttctgaagc caggctgctt cttcggagta caccctcctg     6840

agccaggagc acaagcacta gcagaaagca gggattgttt caggaaagcc catttaccct     6900

cagtaggaag gcagcctggt cacttgaaca gcacagctga ggctgcttct ctcaatttac     6960

tcattttgca aagaattgac ctctaccaac tcattaggga gaggaaaaag aatcacttag     7020

taattttaaa tcatatgaga agtcctgtac caagtgccaa caactgcaaa gaaatgcagc     7080

tagaggaatg tattgaaatt actactgggt cttccttttt aatgagaaaa tgacaaaaat     7140

ggttgctgta gccctgcctg attttgtaca cgtttgtcta agaattgagt tggcacttaa     7200

gctcacttct caaagtataa taatattgta tgacctcatt tgtcctttca caaaagcact     7260

tgcatcattt ccttaagtca tctgctccct gacatgtttt cttccctaat aaacaacttc     7320

tgtctgttat tcctgccaat gatgttctgt ttctgatgcc atatcctatt gagcgtgccc     7380

ctgtactaat atcattgaaa atattgatat gcaaacacat ttccttttca tccccattct     7440

atctttccct ttggggacag attgctttcc aaaagctcat gaacaaatat ttggaatgct     7500

ggtacctttg gggcagaggt aagggtgggc ggggtggggg cagaaaggta atgcttaatg     7560

cagataactc ttctaatcag tgtccatggc aatatgaacg cttgaagaaa actcagtgac     7620

atatcttgct cagtagtttc ttattcctga agaaccacaa gcataaagtg aggcctcagt     7680

gctggtgctc ttggagtatg gggaatgtgc aaatatttaa ctgttttgta tgctgcacat     7740

tgcaggtctg ctcatgtgca ttctcccttt gtcttccttt gtcatatgtg tttttgcttt     7800

tttgaaagtg cagtctttat tgtaccctcc tccagcttgt agcaaattag aatgcttagc     7860

atttatgttc attcattatt gtatttgcca tgtaaaattt ttattacctt agacaagctt     7920

ataagctgtt actacataac ttatcttact gtaactcttt tatttccccc gacgttgtaa     7980

tttgtttgtg atgtatattg tgaaattgta ttctatgtta atttaatcag cacaattcac     8040

tgacatgctg gactgacatg ctggctgctg tttcaaagtg taaagtttgt gtagggctgt     8100

tgggacaact gcaactctgt tgtcaaggta ctgtgctttg gttcctatag caacactggg     8160

tgtggccctt gaattgctaa gggcatttaa tacatcctgg agcaaatttt aactgcagat     8220

tttctttgta gaaattctat gtataatgca ggtacctact tggcccatgg ctggtaacta     8280

tttgggcaat tagaaaaaaa gaaaaaaaca taaaaactag tgtctattgc tgctttgaat     8340

atgtttgaaa gtctgaaaat gtaaatagtt tatcaaaaaa aaatcttgta cagtccagtg     8400

taaagttttt aaatgacctt aagggttgcc atcacatctt tctcacactc tcctcttgat     8460

aataataata ataaaaagtt tgctaaggat taaagaaatg ggaaaaataa aaaaaatctc     8520

ttcaaattta caggaatgaa tcattgttct tagctttgtt gcatacacaa acttcttgga     8580

ttttgttgtg cagtattgac gtgagataaa gctcaacatt gaataatctt tcagtggtac     8640

ttttcaaagt cttcccctcc tctgcctcat aattaaggga aaagacaaaa ttgaaagaca     8700

cactgtcttt atctatcctg gtgtatgttg gcaccttagc tacttttttt ttttcctttt     8760

tgcacaaggt gctttcctga tatgttcaac atgccatctt tgggtgataa tgtatatgcc     8820

gtgatggggc tcaggcccct taggggagtg tctataagaa ctgcctattt atgctcattt     8880

acctcaagac tgtcctctct accctaatct agttgtcatc actccatctt ttgtactgct     8940

gttgacactt acaaattaaa gataaatttt gttttatga                            8979


<210>  148
<211>  4176
<212>  DNA
<213>  homo sapiens

<400>  148
cttctggatg tgagacaggc ggatctcacc cacgcctgcc agcagctcct cggagaactg       60

tgttcctggg tcagccctgg cccagaggag cgccggggac ccgcagagtg ctgctgaagt      120

caaggctaca actcacctag gatctggggc gccagccctc cggtgggcag ggcgttctcc      180

tcccccaccc cctccccgca cgatgacatc aagtgtttgg cgttgagttg ctccataaaa      240

gctgcccggg gaagccagga gagcgaaggg cggacgtact cgccacggca cccaggctgc      300

gcgcacgcgg tcccggtgtg cagctggaga gcgagcggcc accgggagcc cccggcacag      360

cccgcgcccg ccccgcagga gcccgcgaag atgccccggc gcagcctgca cgcggcggcc      420

gtgctcctgc tggtgatctt aaaggaacag ccttccagcc cggccccagt gaacggttcc      480

aagtggactt attttggtcc tgatggggag aatagctggt ccaagaagta cccgtcgtgt      540

gggggcctgc tgcagtcccc catagacctg cacagtgaca tcctccagta tgacgccagc      600

ctcacgcccc tcgagttcca aggctacaat ctgtctgcca acaagcagtt tctcctgacc      660

aacaatggcc attcagtgaa gctgaacctg ccctcggaca tgcacatcca gggcctccag      720

tctcgctaca gtgccacgca gctgcacctg cactggggga acccgaatga cccgcacggc      780

tctgagcaca ccgtcagcgg acagcacttc gccgccgagc tgcacattgt ccattataac      840

tcagaccttt atcctgacgc cagcactgcc agcaacaagt cagaaggcct cgctgtcctg      900

gctgttctca ttgagatggg ctccttcaat ccgtcctatg acaagatctt cagtcacctt      960

caacatgtaa agtacaaagg ccaggaagca ttcgtcccgg gattcaacat tgaagagctg     1020

cttccggaga ggaccgctga atattaccgc taccgggggt ccctgaccac acccccttgc     1080

aaccccactg tgctctggac agttttccga aaccccgtgc aaatttccca ggagcagctg     1140

ctggctttgg agacagccct gtactgcaca cacatggacg acccttcccc cagagaaatg     1200

atcaacaact tccggcaggt ccagaagttc gatgagaggc tggtatacac ctccttctcc     1260

caaggcatca tcctctcact ggccctggct ggcattcttg gcatctgtat tgtggtggtg     1320

gtgtccattt ggcttttcag aaggaagagt atcaaaaaag gtgataacaa gggagtcatt     1380

tacaagccag ccaccaagat ggagactgag gcccacgctt gaggtccccg gagctcccgg     1440

gcacatccag gaaggacctt gctttggacc ctacacactt cggctctctg gacacttgcg     1500

acacctcaag gtgttctctg tagctcaatc tgcaaacatg ccaggcctca gggatcctct     1560

gctgggtgcc tccttgcctt gggaccatgg ccaccccaga gccatccgat cgatggatgg     1620

gatgcactct cagaccaagc agcaggaatt caaagctgct tgctgtaact gtgtgagatt     1680

gtgaagtggt ctgaattctg gaatcacaaa ccaagccatg ctggtgggcc attaatggtt     1740

ggaaaacact ttcatccggg gctttgccag agcgtgcttt caagtgtcct ggaaattctg     1800

ctgcttctcc aagctttcag acaagaatgt gcactctctg cttaggtttt gcttgggaaa     1860

ctcaacttct ttcctctgga gacggggcat ctccctctga tttccttctg ctatgacaaa     1920

acctttaatc tgcaccttac aactcgggga caaatgggga caggaaggat caagttgtag     1980

agagaaaaag aaaacaagag atatacattg tgatatatta gggacacttt cacagtcctg     2040

tcctctggat cacagacact gcacagacct tagggaatgg caggttcaag ttccacttct     2100

tggtggggat gagaagggag agagagctag agggacaaag agaatgagaa gacatggatg     2160

atctgggaga gtctcacttt ggaatcagaa ttggaatcac attctgttta tcaagccata     2220

atgtaaggac agaataatac aatattaagt ccaaatccaa cctcctgtca gtggagcagt     2280

tatgttttat actctacaga ttttacaaat aatgaggctg ttccttgaaa atgtgttgtt     2340

gctgtgtcct ggaggagaca tgagttccga gatgacccaa tctgcctttg aatctggagg     2400

aaataggcag aaacaaaatg actgtagaac ttattctctg taggccaaat ttcatttcag     2460

ccacttctgc aggatcccta ctgccaacct ggaatggaga cttttatcta cttctctctc     2520

tctgaagatg tcaaatcgtg gtttagatca aatatatttc aagctataaa agcaggaggt     2580

tatctgtgca gggggctggc atcatgtatt taggggcaag taataatgga atgctactaa     2640

gatactccat attcttcccc gaatcacaca gacagtttct gacaggcgca actcctccat     2700

tttcctcccg caggtgagaa ccctgtggag atgagtcagt gccatgactg agaaggaacc     2760

gacccctagt tgagagcacc ttgcagttcc ccgagaactt tctgattcac agtctcattt     2820

tgacagcatg aaatgtcctc ttgaagcata gctttttaaa tatctttttc cttctactcc     2880

tccctctgac tctaagaatt ctctcttctg gaatcgcttg aacccaggag gcggaggttg     2940

cagtaagcca aggtcatgcc actgcactct agcctgggtg acagagcgag actccatctc     3000

aaaaaaaaaa aaaaaaaaat tattctgtac catcacaact tttcacaacg atggcaagcc     3060

ttatgtcttg ggagcctgtt ttgctaggca aagttacaag tgacctaatg ggagctcaaa     3120

tgtgtgtgtg tctctctgtg tgtttgtgtg tgtgtgtgca ctcaagacct ctaacagcct     3180

cgaagcctgg ggtggcatcc cggccttgcc attagcatgc ctcatgcatc atcagatgac     3240

aaggacaacc ctcatgacga agcaacatga attagggggc ctcttggcct tggtccaaaa     3300

ttgtcaatca gaaatgaaca taaaggactc cagagcagtg ggactgtctg tcaaaagact     3360

ctgtatatct tttgtggatg agttttgtga gagaacagag agaccattgt acctggcaca     3420

agggctgttc atgaaaaggg agacttactg ggaggtgcaa gacagtggca tttctcctct     3480

cctcttgctg ctcagcacag ccctggattg cagccccgag gctgagacca gacaaagccc     3540

gggaggcaga aagatgctcc aagaaccaac actatcaatg tctttgcaaa tcctcacagg     3600

attcctgtgg gtccagcttt ggaactggga aacctttctt cggatccgca ctcattccac     3660

tgatgccagc tgcccctgaa ggatgccagt actgtggtgt gtgagtctca gcagccgccc     3720

acacgctcct aactctgctg catggcagat gcctaggtgg aaatagcaaa aacaaggccc     3780

aggctggggc cagggccaga ggggaaggcc ctggattctc actcatgtga gatcttgaat     3840

ctctttcttt gttctgtttg tttagttagt atcatctggt aaaatagtta aaaaacaaca     3900

aaaaactctg tatctgtttc tagcatgtgc tgcattgact ctattaatca catttcaaat     3960

tcaccctaca ttcctctcct cttcactagc ctctctgaag gtgtcctggc cagccctgga     4020

gaagcactgg tgtctgcagc acccctcagt tcctgtgcct cagcccacag gccactgtga     4080

taatggtctg tttagcactt ctgtatttat tgtaagaatg attataatga agatacacac     4140

tgtaactaca agaaattata aatgtttttc acatca                               4176


<210>  149
<211>  4176
<212>  DNA
<213>  homo sapiens

<400>  149
cttctggatg tgagacaggc ggatctcacc cacgcctgcc agcagctcct cggagaactg       60

tgttcctggg tcagccctgg cccagaggag cgccggggac ccgcagagtg ctgctgaagt      120

caaggctaca actcacctag gatctggggc gccagccctc cggtgggcag ggcgttctcc      180

tcccccaccc cctccccgca cgatgacatc aagtgtttgg cgttgagttg ctccataaaa      240

gctgcccggg gaagccagga gagcgaaggg cggacgtact cgccacggca cccaggctgc      300

gcgcacgcgg tcccggtgtg cagctggaga gcgagcggcc accgggagcc cccggcacag      360

cccgcgcccg ccccgcagga gcccgcgaag atgccccggc gcagcctgca cgcggcggcc      420

gtgctcctgc tggtgatctt aaaggaacag ccttccagcc cggccccagt gaacggttcc      480

aagtggactt attttggtcc tgatggggag aatagctggt ccaagaagta cccgtcgtgt      540

gggggcctgc tgcagtcccc catagacctg cacagtgaca tcctccagta tgacgccagc      600

ctcacgcccc tcgagttcca aggctacaat ctgtctgcca acaagcagtt tctcctgacc      660

aacaatggcc attcagtgaa gctgaacctg ccctcggaca tgcacatcca gggcctccag      720

tctcgctaca gtgccacgca gctgcacctg cactggggga acccgaatga cccgcacggc      780

tctgagcaca ccgtcagcgg acagcacttc gccgccgagc tgcacattgt ccattataac      840

tcagaccttt atcctgacgc cagcactgcc agcaacaagt cagaaggcct cgctgtcctg      900

gctgttctca ttgagatggg ctccttcaat ccgtcctatg acaagatctt cagtcacctt      960

caacatgtaa agtacaaagg ccaggaagca ttcgtcccgg gattcaacat tgaagagctg     1020

cttccggaga ggaccgctga atattaccgc taccgggggt ccctgaccac acccccttgc     1080

aaccccactg tgctctggac agttttccga aaccccgtgc aaatttccca ggagcagctg     1140

ctggctttgg agacagccct gtactgcaca cacatggacg acccttcccc cagagaaatg     1200

atcaacaact tccggcaggt ccagaagttc gatgagaggc tggtatacac ctccttctcc     1260

caaggcatca tcctctcact ggccctggct ggcattcttg gcatctgtat tgtggtggtg     1320

gtgtccattt ggcttttcag aaggaagagt atcaaaaaag gtgataacaa gggagtcatt     1380

tacaagccag ccaccaagat ggagactgag gcccacgctt gaggtccccg gagctcccgg     1440

gcacatccag gaaggacctt gctttggacc ctacacactt cggctctctg gacacttgcg     1500

acacctcaag gtgttctctg tagctcaatc tgcaaacatg ccaggcctca gggatcctct     1560

gctgggtgcc tccttgcctt gggaccatgg ccaccccaga gccatccgat cgatggatgg     1620

gatgcactct cagaccaagc agcaggaatt caaagctgct tgctgtaact gtgtgagatt     1680

gtgaagtggt ctgaattctg gaatcacaaa ccaagccatg ctggtgggcc attaatggtt     1740

ggaaaacact ttcatccggg gctttgccag agcgtgcttt caagtgtcct ggaaattctg     1800

ctgcttctcc aagctttcag acaagaatgt gcactctctg cttaggtttt gcttgggaaa     1860

ctcaacttct ttcctctgga gacggggcat ctccctctga tttccttctg ctatgacaaa     1920

acctttaatc tgcaccttac aactcgggga caaatgggga caggaaggat caagttgtag     1980

agagaaaaag aaaacaagag atatacattg tgatatatta gggacacttt cacagtcctg     2040

tcctctggat cacagacact gcacagacct tagggaatgg caggttcaag ttccacttct     2100

tggtggggat gagaagggag agagagctag agggacaaag agaatgagaa gacatggatg     2160

atctgggaga gtctcacttt ggaatcagaa ttggaatcac attctgttta tcaagccata     2220

atgtaaggac agaataatac aatattaagt ccaaatccaa cctcctgtca gtggagcagt     2280

tatgttttat actctacaga ttttacaaat aatgaggctg ttccttgaaa atgtgttgtt     2340

gctgtgtcct ggaggagaca tgagttccga gatgacccaa tctgcctttg aatctggagg     2400

aaataggcag aaacaaaatg actgtagaac ttattctctg taggccaaat ttcatttcag     2460

ccacttctgc aggatcccta ctgccaacct ggaatggaga cttttatcta cttctctctc     2520

tctgaagatg tcaaatcgtg gtttagatca aatatatttc aagctataaa agcaggaggt     2580

tatctgtgca gggggctggc atcatgtatt taggggcaag taataatgga atgctactaa     2640

gatactccat attcttcccc gaatcacaca gacagtttct gacaggcgca actcctccat     2700

tttcctcccg caggtgagaa ccctgtggag atgagtcagt gccatgactg agaaggaacc     2760

gacccctagt tgagagcacc ttgcagttcc ccgagaactt tctgattcac agtctcattt     2820

tgacagcatg aaatgtcctc ttgaagcata gctttttaaa tatctttttc cttctactcc     2880

tccctctgac tctaagaatt ctctcttctg gaatcgcttg aacccaggag gcggaggttg     2940

cagtaagcca aggtcatgcc actgcactct agcctgggtg acagagcgag actccatctc     3000

aaaaaaaaaa aaaaaaaaat tattctgtac catcacaact tttcacaacg atggcaagcc     3060

ttatgtcttg ggagcctgtt ttgctaggca aagttacaag tgacctaatg ggagctcaaa     3120

tgtgtgtgtg tctctctgtg tgtttgtgtg tgtgtgtgca ctcaagacct ctaacagcct     3180

cgaagcctgg ggtggcatcc cggccttgcc attagcatgc ctcatgcatc atcagatgac     3240

aaggacaacc ctcatgacga agcaacatga attagggggc ctcttggcct tggtccaaaa     3300

ttgtcaatca gaaatgaaca taaaggactc cagagcagtg ggactgtctg tcaaaagact     3360

ctgtatatct tttgtggatg agttttgtga gagaacagag agaccattgt acctggcaca     3420

agggctgttc atgaaaaggg agacttactg ggaggtgcaa gacagtggca tttctcctct     3480

cctcttgctg ctcagcacag ccctggattg cagccccgag gctgagacca gacaaagccc     3540

gggaggcaga aagatgctcc aagaaccaac actatcaatg tctttgcaaa tcctcacagg     3600

attcctgtgg gtccagcttt ggaactggga aacctttctt cggatccgca ctcattccac     3660

tgatgccagc tgcccctgaa ggatgccagt actgtggtgt gtgagtctca gcagccgccc     3720

acacgctcct aactctgctg catggcagat gcctaggtgg aaatagcaaa aacaaggccc     3780

aggctggggc cagggccaga ggggaaggcc ctggattctc actcatgtga gatcttgaat     3840

ctctttcttt gttctgtttg tttagttagt atcatctggt aaaatagtta aaaaacaaca     3900

aaaaactctg tatctgtttc tagcatgtgc tgcattgact ctattaatca catttcaaat     3960

tcaccctaca ttcctctcct cttcactagc ctctctgaag gtgtcctggc cagccctgga     4020

gaagcactgg tgtctgcagc acccctcagt tcctgtgcct cagcccacag gccactgtga     4080

taatggtctg tttagcactt ctgtatttat tgtaagaatg attataatga agatacacac     4140

tgtaactaca agaaattata aatgtttttc acatca                               4176


<210>  150
<211>  3315
<212>  DNA
<213>  homo sapiens

<400>  150
aataaatttc tctgtgattg gttggtgaag gttttcaaac cggagctgtg ggcgcggcgc       60

tgctctgccg ttgggtgagg cgcggagcga agtgaagggt ggcccaggtg gggccaggct      120

gactgaatgt atctcctagc tatggactaa ataatacatg gggggaaata aacaagtatt      180

catgagggtg aaaatgtgac ccagcaggaa aattacaact attttcaatt gacgttgaat      240

aggatgagtc atggaattta agtgatttac tgaagattat actactggta gatagaagag      300

ctaaagaaag atggatacta tgatgctgaa tgtgcggaat ctgtttgagc agcttgtgcg      360

ccgggtggag attctcagtg aaggaaatga agtccaattt atccagttgg cgaaggactt      420

tgaggatttc cgtaaaaagt ggcagaggac tgaccatgag ctggggaaat acaaggatct      480

tttgatgaaa gcagagactg agcgaagtgc tctggatgtt aagctgaagc atgcacgtaa      540

tcaggtggat gtagagatca aacggagaca gagagctgag gctgactgcg aaaagctgga      600

acgacagatt cagctgattc gagagatgct catgtgtgac acatctggca gcattcaact      660

aagcgaggag caaaaatcag ctctggcttt tctcaacaga ggccaaccat ccagcagcaa      720

tgctgggaac aaaagactat caaccattga tgaatctggt tccattttat cagatatcag      780

ctttgacaag actgatgaat cactggattg ggactcttct ttggtgaaga ctttcaaact      840

gaagaagaga gaaaagaggc gctctactag ccgacagttt gttgatggtc cccctggacc      900

tgtaaagaaa actcgttcca ttggctctgc agtagaccag gggaatgaat ccatagttgc      960

aaaaactaca gtgactgttc ccaatgatgg cgggcccatc gaagctgtgt ccactattga     1020

gactgtgcca tattggacca ggagccgaag gaaaacaggt actttacaac cttggaacag     1080

tgactccacc ctgaacagca ggcagctgga gccaagaact gagacagaca gtgtgggcac     1140

gccacagagt aatggaggga tgcgcctgca tgactttgtt tctaagacgg ttattaaacc     1200

tgaatcctgt gttccatgtg gaaagcggat aaaatttggc aaattatctc tgaagtgtcg     1260

agactgtcgt gtggtctctc atccagaatg tcgggaccgc tgtccccttc cctgcattcc     1320

taccctgata ggaacacctg tcaagattgg agagggaatg ctggcagact ttgtgtccca     1380

gacttctcca atgatcccct ccattgttgt gcattgtgta aatgagattg agcaaagagg     1440

tctgactgag acaggcctgt ataggatctc tggctgtgac cgcacagtaa aagagctgaa     1500

agagaaattc ctcagagtga aaactgtacc cctcctcagc aaagtggatg atatccatgc     1560

tatctgtagc cttctaaaag actttcttcg aaacctcaaa gaacctcttc tgacctttcg     1620

ccttaacaga gcctttatgg aagcagcaga aatcacagat gaagacaaca gcatagctgc     1680

catgtaccaa gctgttggtg aactgcccca ggccaacagg gacacattag ctttcctcat     1740

gattcacttg cagagagtgg ctcagagtcc acatactaaa atggatgttg ccaatctggc     1800

taaagtcttt ggccctacaa tagtggccca tgctgtgccc aatccagacc cagtgacaat     1860

gttacaggac atcaagcgtc aacccaaggt ggttgagcgc ctgctttcct tgcctctgga     1920

gtattggagt cagttcatga tggtggagca agagaacatt gaccccctac atgtcattga     1980

aaactcaaat gccttttcaa caccacagac accagatatt aaagtgagtt tactgggacc     2040

tgtgaccact cctgaacatc agcttctcaa gactccttca tctagttccc tgtcacagag     2100

agtccgttcc accctcacca agaacactcc tagatttggg agcaaaagca agtctgccac     2160

taacctagga cgacaaggca acttttttgc ttctccaatg ctcaagtgaa gtcacatctg     2220

cctgttactt cccagcattg actgactata agaaaggaca catctgtact ctgctctgca     2280

gcctcctgta ctcattacta cttttagcat tctccaggct tttactcaag tttaattgtg     2340

catgagggtt ttattaaaac tatatatatc tccccttcct tctcctcaag tcacataata     2400

tcagcacttt gtgctggtca ttgttgggag cttttagatg agacatcttt ccaggggtag     2460

aagggttagt atggaattgg ttgtgattct ttttggggaa gggggttatt gttcctttgg     2520

cttaaagcca aatgctgctc atagaatgat ctttctctag tttcatttag aactgatttc     2580

cgtgagacaa tgacagaaac cctacctatc tgataagatt agcttgtctc agggtgggaa     2640

gtgggagggc agggcaaaga aaggattaga ccagaggatt taggatgcct ccttctaaga     2700

accagaagtt ctcattcccc attatgaact gagctataat atggagcttt cataaaaatg     2760

ggatgcattg aggacagaac tagtgatggg agtatgcgta gctttgattt ggatgattag     2820

gtctttaata gtgttgagtg gcacaacctt gtaaatgtga aagtacaact cgtatttatc     2880

tctgatgtgc tgctggctga actttgggtt catttggggt caaagccagt ttttctttta     2940

aaattgaatt cattctgatg cttggccccc atacccccaa ccttgtccag tggagcccaa     3000

cttctaaagg tcaatatatc atcctttggc atcccaacta acaataaaga gtaggctata     3060

agggaagatt gtcaatattt tgtggtaaga aaagctacag tcattttttc tttgcacttt     3120

ggatgctgaa atttttccca tggaacatag ccacatctag atagatgtga gctttttctt     3180

ctgttaaaat tattcttaat gtctgtaaaa acgattttct tctgtagaat gtttgacttc     3240

gtattgaccc ttatctgtaa aacacctatt tgggataata tttggaaaaa aagtaaatag     3300

ctttttcaaa atgaa                                                      3315


<210>  151
<211>  2098
<212>  DNA
<213>  homo sapiens

<400>  151
ttgggaaggg tttccagaag gtgggaaatg tcacctgatt cacactgaac ttttgaaagc       60

tccccacccc caaggagccg cgcacaccct cgctcgcggc cgccctccca cagccccaca      120

cactgggaga ccgcccaccg caaaccgcgg agacccccgt ctagatttaa agcgcggctg      180

cgcccggctt ctgacgtcca ttgaatcgcg cgggcggccg gcggcgagcg cggggctgcg      240

ccgggatcgc tgcgccctcc gccgctggcc tctgcgacgc gcgccgctcg cccgagccac      300

ccgccgccgc gccggctccc cgcgccgctg cgctcctcgc cccgcgcctg cccccaggat      360

ggtccgcgcg aggcaccagc cgggtgggct ttgcctcctg ctgctgctgc tctgccagtt      420

catggaggac cgcagtgccc aggctgggaa ctgctggctc cgtcaagcga agaacggccg      480

ctgccaggtc ctgtacaaga ccgaactgag caaggaggag tgctgcagca ccggccggct      540

gagcacctcg tggaccgagg aggacgtgaa tgacaacaca ctcttcaagt ggatgatttt      600

caacgggggc gcccccaact gcatcccctg taaagaaacg tgtgagaacg tggactgtgg      660

acctgggaaa aaatgccgaa tgaacaagaa gaacaaaccc cgctgcgtct gcgccccgga      720

ttgttccaac atcacctgga agggtccagt ctgcgggctg gatgggaaaa cctaccgcaa      780

tgaatgtgca ctcctaaagg caagatgtaa agagcagcca gaactggaag tccagtacca      840

aggcagatgt aaaaagactt gtcgggatgt tttctgtcca ggcagctcca catgtgtggt      900

ggaccagacc aataatgcct actgtgtgac ctgtaatcgg atttgcccag agcctgcttc      960

ctctgagcaa tatctctgtg ggaatgatgg agtcacctac tccagtgcct gccacctgag     1020

aaaggctacc tgcctgctgg gcagatctat tggattagcc tatgagggaa agtgtatcaa     1080

agcaaagtcc tgtgaagata tccagtgcac tggtgggaaa aaatgtttat gggatttcaa     1140

ggttgggaga ggccggtgtt ccctctgtga tgagctgtgc cctgacagta agtcggatga     1200

gcctgtctgt gccagtgaca atgccactta tgccagcgag tgtgccatga aggaagctgc     1260

ctgctcctca ggtgtgctac tggaagtaaa gcactccgga tcttgcaact gaatctgccc     1320

gtaaaacctg agccattgat tcttcagaac tttctgcagt ttttgacttc atagattatg     1380

ctttaaaaaa atttttttaa cttattgcat aacagcagat gccaaaaaca aaaaaagcat     1440

ctcactgcaa gtcacataaa aatgcaacgc tgtaatatgg ctgtatcaga gggctttgaa     1500

aacatacact gagctgcttc tgcgctgttg ttgtccgtat ttaaacaaca gctcccctgt     1560

attcccccat ctagccattt cggaagacac cgaggaagag gaggaagatg aagaccagga     1620

ctacagcttt cctatatctt ctattctaga gtggtaaact ctctataagt gttcagtgtt     1680

gacatagcct ttgtgcaaaa aaaaaaaaaa aaaaaaagaa aaagaaaaaa agaaaaatat     1740

attgtccata ctgtaaataa gtgtatgctt atttatttgg ggggaaaact atacattaaa     1800

ggacctttgt cctaaagctc tctcccaggc caccttgtta ctcattggac acggagaggc     1860

attcattgtg aggtctactg gatgaggccc atagttgaga cttgtagaca tttatttata     1920

ctgtgtcatg ttttataatt tatacataaa atgtctggtt gactgtatac cttgtttttg     1980

aagaaattta ttcgtgaaag gaagagcagt tgttatttat tgtgaggtct cttgcttgta     2040

aagtaaaagc tttttttcct tgtaaaccat ttaagtccat tccttactat tcactcac       2098


<210>  152
<211>  1834
<212>  DNA
<213>  homo sapiens

<400>  152
ttgggaaggg tttccagaag gtgggaaatg tcacctgatt cacactgaac ttttgaaagc       60

tccccacccc caaggagccg cgcacaccct cgctcgcggc cgccctccca cagccccaca      120

cactgggaga ccgcccaccg caaaccgcgg agacccccgt ctagatttaa agcgcggctg      180

cgcccggctt ctgacgtcca ttgaatcgcg cgggcggccg gcggcgagcg cggggctgcg      240

ccgggatcgc tgcgccctcc gccgctggcc tctgcgacgc gcgccgctcg cccgagccac      300

ccgccgccgc gccggctccc cgcgccgctg cgctcctcgc cccgcgcctg cccccaggat      360

ggtccgcgcg aggcaccagc cgggtgggct ttgcctcctg ctgctgctgc tctgccagtt      420

catggaggac cgcagtgccc aggctgggaa ctgctggctc cgtcaagcga agaacggccg      480

ctgccaggtc ctgtacaaga ccgaactgag caaggaggag tgctgcagca ccggccggct      540

gagcacctcg tggaccgagg aggacgtgaa tgacaacaca ctcttcaagt ggatgatttt      600

caacgggggc gcccccaact gcatcccctg taaagaaacg tgtgagaacg tggactgtgg      660

acctgggaaa aaatgccgaa tgaacaagaa gaacaaaccc cgctgcgtct gcgccccgga      720

ttgttccaac atcacctgga agggtccagt ctgcgggctg gatgggaaaa cctaccgcaa      780

tgaatgtgca ctcctaaagg caagatgtaa agagcagcca gaactggaag tccagtacca      840

aggcagatgt aaaaagactt gtcgggatgt tttctgtcca ggcagctcca catgtgtggt      900

ggaccagacc aataatgcct actgtgtgac ctgtaatcgg atttgcccag agcctgcttc      960

ctctgagcaa tatctctgtg ggaatgatgg agtcacctac tccagtgcct gccacctgag     1020

aaaggctacc tgcctgctgg gcagatctat tggattagcc tatgagggaa agtgtatcaa     1080

agcaaagtcc tgtgaagata tccagtgcac tggtgggaaa aaatgtttat gggatttcaa     1140

ggttgggaga ggccggtgtt ccctctgtga tgagctgtgc cctgacagta agtcggatga     1200

gcctgtctgt gccagtgaca atgccactta tgccagcgag tgtgccatga aggaagctgc     1260

ctgctcctca ggtgtgctac tggaagtaaa gcactccgga tcttgcaact ccatttcgga     1320

agacaccgag gaagaggagg aagatgaaga ccaggactac agctttccta tatcttctat     1380

tctagagtgg taaactctct ataagtgttc agtgttgaca tagcctttgt gcaaaaaaaa     1440

aaaaaaaaaa aaagaaaaag aaaaaaagaa aaatatattg tccatactgt aaataagtgt     1500

atgcttattt atttgggggg aaaactatac attaaaggac ctttgtccta aagctctctc     1560

ccaggccacc ttgttactca ttggacacgg agaggcattc attgtgaggt ctactggatg     1620

aggcccatag ttgagacttg tagacattta tttatactgt gtcatgtttt ataatttata     1680

cataaaatgt ctggttgact gtataccttg tttttgaaga aatttattcg tgaaaggaag     1740

agcagttgtt atttattgtg aggtctcttg cttgtaaagt aaaagctttt tttccttgta     1800

aaccatttaa gtccattcct tactattcac tcac                                 1834


<210>  153
<211>  4929
<212>  DNA
<213>  homo sapiens

<400>  153
aatgagctgt ctgcagcaga gctgagagga ccagccattt tacttatgga aaacagtgtg       60

gcatattctg ctgagcttcg ccctggaaga agcctctttt atacatctct tcagggaaga      120

gagaagcaat gggcatgtta gtatacaatg atcacagcca cgcaggcctg caagctgcct      180

tttggacagg ctgttgactg ccgttccaat tagctgattg gagaatgtgg aatgcagagt      240

gataatgctg catatctgct atcaggcagc agcaaaggtt tttgtcttgg gaaggcaagc      300

tttccctgca atattatctc agcagctccc tagctgctta ccctgaaaac gagggatcca      360

aacggagggt gttgcactct gctaacgctg gtcctgtgcg tggctgtggc atatgagcgg      420

caggtctgaa aaagcaggtg tgtgctggga cgggcactgg actggaacgc aggcggacgc      480

tctcgggttt acctgcttcc tgttaacaga ttgtgggctc ccagggcata tgtctgcacg      540

ctgaggccga ggcggagaag gggcttcctg agcgtcccag tacactgaca gagacacttg      600

gattggactt aatcttaaac ctctggagtt caagaccttt taaaaagggc taaataaaca      660

atctctacat gtaaaaggcc actgactcct acttcctctg tatagagcaa ctgttgaact      720

cagctgcctg taggaaaact gaagacttta ataacaaact ctccaaggtg aaaatgaaca      780

cagcggtggg tgtgctcgca aacgtgccgc catgtctgtt acgctaacat ctgtgaagag      840

agtgcaaagt tctccaaacc tattggctgc agggcgtgat tctcagtcac cagactcagc      900

ttggagatct tacaatgatg gcaatcagga gacactgaac ggagatgcta catattcctc      960

tcttgcagca aaaggtttta gaagcgttcg accaaaccta caagataaaa gatcaccaac     1020

tcagagccag ataacagtga atggaaactc aggaggtgcc gtgagtccca tgagttacta     1080

tcagaggccg ttttccccct cggcatattc tctcccagcc tcactcaact ccagcattgt     1140

catgcagcac ggcacatccc tcgattccac agacacatat ccccagcatg cgcagtctct     1200

ggatggcacc accagcagct ctatccccct gtaccgatcc tcagaggaag agaagagagt     1260

gacagtcatc aaagccccgc attacccagg gatcgggccc gtggatgaat ccggaatccc     1320

cacagcaatt agaacgacag tcgaccggcc caaggactgg tacaagacga tgtttaagca     1380

aattcacatg gtgcacaagc cgggtctgta caacccaccc tacagtgctc agtcacaccc     1440

tgctgcaaag acccaaacct acagacctct ttccaaaagc cactccgaca acagccccaa     1500

tgcctttaag gatgcgtcct ccccagtgcc tcccccacat gttccacctc cagtcccgcc     1560

gcttcgacca agagatcggt cttcaacaga aaagcatgac tgggatcctc cagacagaaa     1620

agtggacaca agaaaatttc ggtctgagcc aaggagtatt tttgaatatg aacctggcaa     1680

gtcatcaatt cttcagcatg aaagaccagc ctccttgtat cagtcctcta tagacagaag     1740

cctggaaaga cccatgagtt ctgcaagcat ggccagtgac ttcaggaagc ggaggaagag     1800

cgagcctgca gtgggtccac cacggggctt gggagatcaa agtgcgagca ggactagccc     1860

aggccgagtg gacctcccag gatcaagcac cactcttaca aagtctttca ctagctcttc     1920

tccttcttcc ccatcaagag caaaagaccg tgagtcccct agaagttact catccacttt     1980

gactgacatg gggagaagtg caccaaggga aagaagagga actccagaaa aagagaaatt     2040

gcctgcaaaa gctgtttatg attttaaggc tcagacatct aaggagttgt catttaagaa     2100

aggagatact gtctacatcc tcaggaaaat tgatcaaaat tggtatgagg gagaacacca     2160

cgggagagtg ggcatcttcc cgatctcata cgtagagaaa ctcacacctc ctgagaaagc     2220

acagcctgca agaccacctc cgccagccca gcccggagaa atcggagaag ctatagccaa     2280

atacaacttc aacgcagaca caaatgtgga gctgtcactg agaaagggag atagagttat     2340

tcttcttaaa agagttgatc aaaactggta tgaaggtaaa atcccaggaa ccaacagaca     2400

aggcatcttc cctgtttcct atgtggaggt cgtcaagaag aacacaaaag gtgctgagga     2460

ctaccctgac cctccaatac cccacagcta ttctagtgat aggattcaca gcttgagctc     2520

aaataagcca cagcgtcctg tgtttactca tgaaaatatt caaggtgggg gggaaccgtt     2580

tcaggctctg tataactata ctcccaggaa tgaagatgag ctggagctca gagaaagtga     2640

tgtcattgat gtcatggaaa agtgtgatga cggctggttt gtggggacct caagaagaac     2700

caaattcttt ggtactttcc ccggaaacta cgtcaagagg ctgtgaattg cgctccctcc     2760

ttctgtagag gccgcctgcc agccatgcac ctgcgtcaac gcgcctgaaa caccccgcgg     2820

gcctcccgtt gtcatgcctt acggtttcca atgcgccgtc accatctcca cctgccacca     2880

aaccaccagc agagtagccg ccgctgctgt gagcctgggg acgacatggc aggctggtcc     2940

ccctccgtga aagtgtggat tcctacttcc tgctctaagc tttgacacgt caaaatgtgg     3000

gatcagaaag aaaaaaatca tgatatttaa aaatggtcaa atatttgagg caaaaaaaaa     3060

aaaaaaaagt gtctccagga ggctgtccag cctcgtggct ccatttcaac atctcccccc     3120

aggcgatgtt ctcccccaag acgaccagaa aattgtttat tggggaatgc tgtggtttgc     3180

attttcatat tcttcgcttg gcagtgtgta ttcttttcac aagtttgcct agtgtcttgg     3240

tttacacaat atgacaactg taactgtact ttagctattg tttgcctgca catacatgtt     3300

gtaatatgca cagtgattac aacctttaaa gcaagaggag gcgagttaat ttggatgagt     3360

gtgattttgc tgattgaatg tgagttttca aataggagtc tttttctgca atttgtttgc     3420

attttttaga agtgcaaaca gtaagtaaat aaaagccttc ggtaataatc atgacaatac     3480

aagaggctga gctaggctac aggggaaaac tattgtgttg taaagttgca tcgctatttt     3540

atattaaaat gtaatgatca gcatcatgaa caatgagctc ttagtgtttt atttatctga     3600

aaaaatgtaa gtaaaagcag tgttagtgag aggtgcaaag aattattcta acagacacct     3660

gaaagtatct gtaagcaata ctagtaggta agatttcact gtgtgtacac atacacattt     3720

gagattgtat gagaacatat aatccatatg atatgttgta cattttatgg aaatgtaata     3780

gaatctcaca cattatttta tagaaataga gtacagaagc atcacaagta ttaaagttgg     3840

ttttagcaag gattaggatt actacaatta tttttactat aataattatt tttcttctat     3900

ggaactcaga atcctggcta catttgagga caggaatatg ttgagcctga ttttcctggt     3960

gtgtgtaaaa tatttcctag gaataaatta ggcacttttt agaagcaatg ttaaatcatt     4020

caggttttat tttctgccct gaagcagaaa tttaaaaaat gatattggga cctggaaggt     4080

ttaatatggt tcacagtgcc tgaattacac ctgctccgaa aactagcttt gtatttctta     4140

tgactttgca taagaactgt tcatctttgg atcttgagca ccttacagat aaaacttttt     4200

atggcatctc tttcatggac agtgatattg atcttttcac aatgtacgta gcctctagaa     4260

ttttgtacat atgtttgctc tttttttgta cagactagtt gttgagaaaa caggggcgtt     4320

tcctaatttg gtctttatcc tgcgacaaca ctttcagcag actagcctct ccttatctca     4380

cagatcacaa gcacccctag atagtgtgat tctgtcagat agcatttatg caaaaatcta     4440

tgaagttaaa agatcgtaga agccaaatga aatgtacata tctactgact gatgacaagg     4500

gaatttcatt aggaagaagg taaagaaaca tcgttgagta gcctaccttg atttctgtca     4560

agttcataac cagcttcata ttttaaaggc ttcaggtttg aaattaagtc aactgcatgc     4620

agctttgctg ataaatgaat aattctcttt gatgccattt atgagaaaag acttcaatat     4680

ctgttgcctg tcatatttaa gaaaaattac tgtttctact ctctgtatct gattttaaaa     4740

gaaaaaacta ttcatacctg gcttccaggt aattgacttt gaattcttac aagcaaaggt     4800

cattgtgttt ttcttgaata gacatctaat aaattttgct tggaagtata cttcagtttt     4860

tcttcttgac atttatcttt ataaaaattg tgtattttat tccaacttgt taaactaaga     4920

gaaaatgca                                                             4929


<210>  154
<211>  2010
<212>  DNA
<213>  homo sapiens

<400>  154
gggtctgcgg gaagcccgag ccggggcggg cccgagtcaa aggcaagtga aggtggaagc       60

ggccgcggcg gcagcaggcc accatggcgg agctgcagga ggtgcagatc acagaggaga      120

agccactgtt gccaggacag acgcctgagg cggccaagac tcactctgtg gagacaccat      180

acggctctgt cactttcact gtctatggca cccccaaacc caaacgccca gcgatcctta      240

cctaccacga tgtgggactc aactataaat cttgcttcca gccactgttt cagttcgagg      300

acatgcagga aatcattcag aactttgtgc gggttcatgt ggatgcccct ggaatggaag      360

agggagcccc tgtgttccct ttgggatatc agtacccatc tctggaccag cttgcagaca      420

tgatcccttg cgtcctgcag tacctaaatt tctctacaat aattggagtt ggtgttggag      480

ctggagccta catcctggcg agatatgctc ttaaccaccc ggacactgtt gaaggtcttg      540

tcctcatcaa cattgatccc aatgccaagg gttggatgga ttgggcagcc cacaagctaa      600

caggcctcac ctcttccatt ccggagatga tccttggaca tcttttcagc caggaagagc      660

tctctggaaa ttctgagttg atacaaaagt acagaaatat cattacacat gcacccaacc      720

tggataacat tgaattgtac tggaacagct acaacaaccg ccgagacctg aactttgagc      780

gtggaggtga tatcaccctc aggtgtcctg tgatgctggt ggtaggagac caagcacctc      840

atgaagatgc agtggtggaa tgtaactcaa aactggaccc cacccagacc tcgttcctca      900

agatggctga ctccggaggt cagccccagc tgactcagcc aggcaagctg accgaggcct      960

tcaagtactt cctgcaaggc atgggctaca tggcctcatc ctgcatgact cgcctgtccc     1020

ggtctcgtac agcctctctg accagtgcag catccgttga tggcaaccgg tcccgctctc     1080

gcaccctgtc ccagagcagc gagtctggaa ctctttcttc ggggcccccg gggcacacca     1140

tggaggtctc ctgttgaatg gcccttgttg ccctagagtg ggacccagcc ctcacctccc     1200

ccagagctaa cctgggaggt gctgaagggg cattgggcca ccgtaagcaa gggaaaaagg     1260

gcagatcatg cggggagatg accttgatct ttgattgcta ccctaacctt gacctttaac     1320

ccgtgattcc ccccagctcc tggaagagat gtcctaatat ctcttaggga cccagacccc     1380

taaattctcc tcctccccca ttttgatgtt aaggtggaga gggcatatgc atcctctgtc     1440

ctgatctagg tgtctatagc tgaggggtaa gaggttgttg tagttgtcct ggtgcctcca     1500

tcagactctc cctacttgtc ccatatttgc aaggggaggg gatttggggc tggggctcca     1560

ttcaccaaag ctgaggtggc ttctcattaa ccctttagga ctctgaaggg tatggaccta     1620

cgtgaatgtg tgtcaggggg agacttgctg gtgggttagt ggtcctcagg atgtgataga     1680

aacatccagt gtaaaaagga agttggaatg ggagttggcg ggcagtgaac gagtgtgggg     1740

aaggattggt gctggggcaa caggaagggg cctggggccg tttggctgca ctaactttgg     1800

tagctcagtg tgcatctaga gtgggactgg ggagggagct aagcttgggc tgggctgctt     1860

ggggcttggc atagggtgga aagggctacc ctggggctct gaccacactg tagtatgtgt     1920

ggagggtgcc ctcccgtctc ccacaacttc tgctataaca ataaactgta gaggaatctg     1980

agtaccgtta aaaaaaaaaa aaaaaaaaaa                                      2010


<210>  155
<211>  3148
<212>  DNA
<213>  homo sapiens

<400>  155
ggagagcgcg ccacagaacg acttttacgc aggcgcagaa gcctgtttcc cctcacccgc       60

ggcttccacc ctgcgcaggc gcaaaaagcc gcgctggcaa cctccgcagc ggtcgcgcgc      120

acccttcacc cctcttgctg cttttgtctg gcacaacctt ctcaggccct ccgcgaggcc      180

ggcccttttt ttctttcact ttccccaccc ggagagccag gtgccgagaa ctaggacctc      240

gtccccttct ctatcccttc ccctgatcca tctcgtctct gttctccttc ccttttccgt      300

tcccgaagcc ggaaggagcc gaggtaccca cggaaaaagt cgaagctgtc cccggagagt      360

gaggccttca cgaagcggtg gcggaaggag ccgaagttct ctgatcggag gcgtgagcaa      420

gtggcatctc cggaaagagc cgaaacacgg actcgagctt aatcccagga ggggcccgag      480

ggcgagatcc ggaaatctcc ggaaagagcc gaaggccggg acggttagga ttgtcggaag      540

tggccgattg cttggacagg gccggcggag aagatcggag caagtccgtg gaagaagcca      600

aagactggga cggattgaat tgttggaaga acccgaactc gcagagggga ctgggcgcag      660

tggcacacga ggacacacgg aaacctccga acgttgagga gataatctcg gaaaagttac      720

ggaaacctgg gaagtcggcg aaaccctacg ttcgggtgtt ttcggaagca gccgaagcgg      780

ccgcctgctt cgccttcgtc cagtatccgg agatagccga ggcgcttcgg agccaggctc      840

ggggggaggg gcaagctcgc gggcgggcgg gcgggtgagg gggcggagcc cgggcggggc      900

ggggagggct gccggaggct tgattaggta ggaggtggcg aagcgccggc ggcggccgga      960

agtagccgaa gccagcggcg gaagtagccg aagcggctgg agcgggcggc aaggcgaggc     1020

gaaagctgca cagggcccta cgcggccgcc tcagcatgtc ggacttcgac gagttcgagc     1080

ggcagctcaa cgagaataaa caagagcggg acaaggagaa ccggcatcgg aagcgcagcc     1140

acagccgctc tcggagccgg gaccgcaaac gccggagccg gagccgcgac cggcgcaacc     1200

gggaccagcg gagcgcctcc cgggacaggc gacgacgcag caaacctttg accagaggcg     1260

ctaaagagga gcacggtgga ctgattcgtt ccccccgcca cgagaagaag aagaaggtcc     1320

gtaaatactg ggacgtgcca cccccaggct ttgagcacat caccccaatg cagtacaagg     1380

ccatgcaagc tgcgggtcag attccagcca ctgctcttct ccccaccatg acccctgacg     1440

gtctggctgt gaccccaacg ccggtgcccg tggtcgggag ccagatgacc agacaagccc     1500

ggcgcctcta cgtgggcaac atcccctttg gcatcactga ggaggccatg atggatttct     1560

tcaacgccca gatgcgcctg ggggggctga cccaggcccc tggcaaccca gtgttggctg     1620

tgcagattaa ccaggacaag aattttgcct ttttggagtt ccgctcagtg gacgagacta     1680

cccaggctat ggcctttgat ggcatcatct tccagggcca gtcactaaag atccgcaggc     1740

ctcacgacta ccagccgctt cctggcatgt cagagaaccc ctccgtctat gtgcctgggg     1800

ttgtgtccac tgtggtcccc gactctgccc acaagctgtt catcgggggc ttacccaact     1860

acctgaacga tgaccaggtc aaagagctgc tgacatcctt tgggcccctc aaggccttca     1920

acctggtcaa ggacagtgcc acggggctct ccaagggcta cgccttctgt gagtacgtgg     1980

acatcaacgt cacggatcag gccattgcgg ggctgaacgg catgcagctg ggggataaga     2040

agctgctggt ccagagggcg agtgtgggag ccaagaatgc cacgctggtg agccccccga     2100

gcaccatcaa tcagacgcct gtgaccctgc aagtgccggg cttgatgagc tcccaggtgc     2160

agatgggcgg ccacccgact gaggtcctgt gcctcatgaa catggtgctg cctgaggagc     2220

tgctggacga cgaggagtat gaggagatcg tggaggatgt gcgggacgag tgcagcaagt     2280

acgggcttgt caagtccatc gagatccccc ggcctgtgga cggcgtcgag gtgcccggct     2340

gcggaaagat ctttgtggag ttcacctctg tgtttgactg ccagaaagcc atgcagggcc     2400

tgacgggccg caagttcgcc aacagagtgg ttgtcacaaa atactgtgac cccgactctt     2460

atcaccgccg ggacttctgg tagaggcggc tgggggaggg tgggggcagg gctggctggg     2520

ggcttctccc cactcccgcc ccccccttat ccccctctga agacgatggg cagaggagtg     2580

acagccgcag acacacgaca gccggcagca actggaatgg cagcaattaa gggtgggggg     2640

cgggggttgg ggggttgggg ggttagggca gggaggggac tggggaagtg cgcacacagc     2700

ccacacagac aacacgcacc cacacagaca cagagggaag gggttgggat ggggacaggg     2760

tgcacagcag ggcggggtag gaccccagcc cctcccaaaa cagcctctcc ttctcccata     2820

gacccctttc ttctcccctt ccccacggta ggaacatagc gtgtttatat tttatggcca     2880

aactattttg aattttgttg tccggccctc agtgccctgc cctctccctt accaggacca     2940

cagctctgtt ccttcggcct ctggtcctct ctggtcccct cctgggtttc ttacgtagtt     3000

gatttttcct ctttagtctc ccccgacctg cgcccagccc cgtggcccct gcccctctcc     3060

tactctctgt ggcagtttca tatttgctaa gacgaatttg ctcattaaac attttgttgt     3120

attttacttt aaaaaaaaaa aaaaaaaa                                        3148


<210>  156
<211>  2172
<212>  DNA
<213>  homo sapiens

<400>  156
cttgaaagta accgcacctt ccaaagggca ccgtgcaatc agactgaaac cacagtgcaa       60

atttaattgc cggggaagat aacgggcctt ggtgccctcc aagcgtcagc tgagtttcca      120

agaagccggg cagcgggcgc ccgcgggttc gtctctggct cctcctccgc cacagcagcc      180

gggggcccgg gtcggaggcg gcgggggccg agcgcccggc ctcgcaagcc cacggcccgc      240

tgggggtgcc gtcccgcgcc ggggcggagc aggccccggc agcccagttc ctcattctat      300

cagcggtaca aggggctggt ggcgccacag gcgctgggac cgcgggcgga caaggatggg      360

tccgcgcggc gcggcgagct tgccccgagg ccccggacct cggcggctgc tcctccccgt      420

cgtcctcccg ctgctgctgc tgctgttgtt ggcgccgccg ggctcgggcg ccggggccag      480

ccggccgccc cacctggtct tcttgctggc agacgaccta ggctggaacg acgtcggctt      540

ccacggctcc cgcatccgca cgccgcacct ggacgcgctg gcggccggcg gggtgctcct      600

ggacaactac tacacgcagc cgctgtgcac gccgtcgcgg agccagctgc tcactggccg      660

ctaccagatc cgtacaggtt tacagcacca aataatctgg ccctgtcagc ccagctgtgt      720

tcctctggat gaaaaactcc tgccccagct cctaaaagaa gcaggttata ctacccatat      780

ggtcggaaaa tggcacctgg gaatgtaccg gaaagaatgc cttccaaccc gccgaggatt      840

tgatacctac tttggatatc tcctgggtag tgaagattat tattcccatg aacgctgtac      900

attaattgac gctctgaatg tcacacgatg tgctcttgat tttcgagatg gcgaagaagt      960

tgcaacagga tataaaaata tgtattcaac aaacatattc accaaaaggg ctatagccct     1020

cataactaac catccaccag agaagcctct gtttctctac cttgctctcc agtctgtgca     1080

tgagcccctt caggtccctg aggaatactt gaagccatat gactttatcc aagacaagaa     1140

caggcatcac tatgcaggaa tggtgtccct tatggatgaa gcagtaggaa atgtcactgc     1200

agctttaaaa agcagtgggc tctggaacaa cacggtgttc atcttttcta cagataacgg     1260

agggcagact ttggcagggg gtaataactg gccccttcga ggaagaaaat ggagcctgtg     1320

ggaaggaggc gtccgagggg tgggctttgt ggcaagcccc ttgctgaagc agaagggcgt     1380

gaagaaccgg gagctcatcc acatctctga ctggctgcca acactcgtga agctggccag     1440

gggacacacc aatggcacaa agcctctgga tggcttcgac gtgtggaaaa ccatcagtga     1500

aggaagccca tcccccagaa ttgagctgct gcataatatt gacccgaact tcgtggactc     1560

ttcaccgtac tggcctgagt gctcgctgct gttgtagcta ccaccaactt tctactgaag     1620

atgataaccc agggcataag aaatgacttc agacccaagg ttctgaaagg gcccctcaag     1680

gcctcgggtg gctcctgcag aagtggcaga agaggcggga actaggaacc tggcatcata     1740

ggaaaagtgc cttctccaag aaagaagggg ccccaggagg ctgtcttact tagatcaacc     1800

ataaactacc acagatgggt catttcttat attatttcaa aatatctttg aagatgagaa     1860

ttcatttgtg tccttcatag accaaagttc tttgtgttac cttttcccaa aagtaaattc     1920

ctttcccttt attcattcct tgtggaaata aaatgcaagc cctttatact tgtcttacag     1980

taatatggca catgtagctt acttttgagc atcccagtga ataatgtttg gaacttttct     2040

tattacctaa tagcatatag agaagagtga agtcagctaa aaacagaaat tttgaaaagc     2100

catcttcagg aaaatgtagg cccagatgct ttcctccacc ttttttgaca ggctgccaca     2160

tacagtttca ca                                                         2172


<210>  157
<211>  2132
<212>  DNA
<213>  homo sapiens

<400>  157
aatggggcgc cgactcggcg caggaacaag gcgggggttc ggggccggct gcagactctc       60

accgcagcgg ccaggaacgc cagccgttca cgcgttcggt cctccttggc tgactcaccg      120

ccctggccgc cgcaccatgg acgcccccag gcaggtggtc aactttgggc ctggtcccgc      180

caagctgccg cactcagtgt tgttagagat acaaaaggaa ttattagact acaaaggagt      240

tggcattagt gttcttgaaa tgagtcacag gtcatcagat tttgccaaga ttattaacaa      300

tacagagaat cttgtgcggg aattgctagc tgttccagac aactataagg tgatttttct      360

gcaaggaggt gggtgcggcc agttcagtgc tgtcccctta aacctcattg gcttgaaagc      420

aggaaggtgt gctgactatg tggtgacagg agcttggtca gctaaggccg cagaagaagc      480

caagaagttt gggactataa atatcgttca ccctaaactt gggagttata caaaaattcc      540

agatccaagc acctggaacc tcaacccaga tgcctcctac gtgtattatt gcgcaaatga      600

gacggtgcat ggtgtggagt ttgactttat acccgatgtc aagggagcag tactggtttg      660

tgacatgtcc tcaaacttcc tgtccaagcc agtggatgtt tccaagtttg gtgtgatttt      720

tgctggtgcc cagaagaatg ttggctctgc tggggtcacc gtggtgattg tccgtgatga      780

cctgctgggg tttgccctcc gagagtgccc ctcggtcctg gaatacaagg tgcaggctgg      840

aaacagctcc ttgtacaaca cgcctccatg tttcagcatc tacgtcatgg gcttggttct      900

ggagtggatt aaaaacaatg gaggtgccgc ggccatggag aagcttagct ccatcaaatc      960

tcaaacaatt tatgagatta ttgataattc tcaaggattc tacgtgtctg tgggaggcat     1020

ccgggcctct ctgtataatg ctgtcacaat tgaagacgtt cagaagctgg ccgccttcat     1080

gaaaaaattt ttggagatgc atcagctatg aacacatcct aaccaggata tactctgttc     1140

ttgaacaaca tacaaagttt aaagtaactt ggggatggct acaaaaagtt aacacagtat     1200

ttttctcaaa tgaacatgtt tattgcagat tcttcttttt tgaaagaaca acagcaaaac     1260

atccacaact ctgtaaagct ggtgggacct aatgtcacct taattctgac ttgaactgga     1320

agcattttaa gaaatcttgt tgcttttcta acaaattccc gcgtattttg cctttgctgc     1380

tactttttct agttagattt caaacttgcc tgtggactta ataatgcaag ttgcgattaa     1440

ttatttctgg agtcatggga acacacagca cagagggtag gggggccctc taggtgctga     1500

atctacacat ctgtggggtc tcctgggttc agcggctgtt gattcaaggt caacattgac     1560

cattggagga gtggtttaag agtgccaggc gaagggcaaa ctgtagatcg atctttatgc     1620

tgttattaca ggagaagtga catactttat atatgtttat attagcaagg tctgttttta     1680

ataccatata ctttatattt ctatacattt atatttctaa taatacagtt atcactgata     1740

tatgtagaca cttttagaat ttattaaatc cttgaccttg tgcattatag cattccatta     1800

gcaagagttg taccccctcc ccagtcttcg ccttcctctt tttaagctgt tttatgaaaa     1860

agacctagaa gttcttgatt catttttacc attctttcca taggtagaag agaaagttga     1920

ttggttggtt gtttttcaat tatgccatta aactaaacat ttctgttaaa ttaccctatc     1980

ctttgttctc tactgttttc tttgtaatgt atgactacga gagtgatact ttgctgaaaa     2040

gtctttcccc tattgtttat ctattgtcag tattttatgt tgaatatgta aagaacatta     2100

aagtcctaaa acatctaaaa aaaaaaaaaa aa                                   2132


<210>  158
<211>  2896
<212>  DNA
<213>  homo sapiens

<400>  158
acgcttgcgc gcgggattta aactgcggcg gtttacgcgg cgttaagact tcgtagggtt       60

agcgaaattg aggtttcttg gtattgcgcg tttctcttcc ttgctgactc tccgaatggc      120

catggactcg tcgcttcagg cccgcctgtt tcccggtctc gctatcaaga tccaacgcag      180

taatggttta attcacagtg ccaatgtaag gactgtgaac ttggagaaat cctgtgtttc      240

agtggaatgg gcagaaggag gtgccacaaa gggcaaagag attgattttg atgatgtggc      300

tgcaataaac ccagaactct tacagcttct tcccttacat ccgaaggaca atctgccctt      360

gcaggaaaat gtaacaatcc agaaacaaaa acggagatcc gtcaactcca aaattcctgc      420

tccaaaagaa agtcttcgaa gccgctccac tcgcatgtcc actgtctcag agcttcgcat      480

cacggctcag gagaatgaca tggaggtgga gctgcctgca gctgcaaact cccgcaagca      540

gttttcagtt cctcctgccc ccactaggcc ttcctgccct gcagtggctg aaataccatt      600

gaggatggtc agcgaggaga tggaagagca agtccattcc atccgaggca gctcttctgc      660

aaaccctgtg aactcagttc ggaggaaatc atgtcttgtg aaggaagtgg aaaaaatgaa      720

gaacaagcga gaagagaaga aggcccagaa ctctgaaatg agaatgaaga gagctcagga      780

gtatgacagt agttttccaa actgggaatt tgcccgaatg attaaagaat ttcgggctac      840

tttggaatgt catccactta ctatgactga tcctatcgaa gagcacagaa tatgtgtctg      900

tgttaggaaa cgcccactga ataagcaaga attggccaag aaagaaattg atgtgatttc      960

cattcctagc aagtgtctcc tcttggtaca tgaacccaag ttgaaagtgg acttaacaaa     1020

gtatctggag aaccaagcat tctgctttga ctttgcattt gatgaaacag cttcgaatga     1080

agttgtctac aggttcacag caaggccact ggtacagaca atctttgaag gtggaaaagc     1140

aacttgtttt gcatatggcc agacaggaag tggcaagaca catactatgg gcggagacct     1200

ctctgggaaa gcccagaatg catccaaagg gatctatgcc atggcctccc gggacgtctt     1260

cctcctgaag aatcaaccct gctaccggaa gttgggcctg gaagtctatg tgacattctt     1320

cgagatctac aatgggaagc tgtttgacct gctcaacaag aaggccaagc tgcgcgtgct     1380

ggaggacggc aagcaacagg tgcaagtggt ggggctgcag gagcatctgg ttaactctgc     1440

tgatgatgtc atcaagatga tcgacatggg cagcgcctgc agaacctctg ggcagacatt     1500

tgccaactcc aattcctccc gctcccacgc gtgcttccaa attattcttc gagctaaagg     1560

gagaatgcat ggcaagttct ctttggtaga tctggcaggg aatgagcgag gcgcggacac     1620

ttccagtgct gaccggcaga cccgcatgga gggcgcagaa atcaacaaga gtctcttagc     1680

cctgaaggag tgcatcaggg ccctgggaca gaacaaggct cacaccccgt tccgtgagag     1740

caagctgaca caggtgctga gggactcctt cattggggag aactctagga cttgcatgat     1800

tgccacgatc tcaccaggca taagctcctg tgaatatact ttaaacaccc tgagatatgc     1860

agacagggtc aaggagctga gcccccacag tgggcccagt ggagagcagt tgattcaaat     1920

ggaaacagaa gagatggaag cctgctctaa cggggcgctg attccaggca atttatccaa     1980

ggaagaggag gaactgtctt cccagatgtc cagctttaac gaagccatga ctcagatcag     2040

ggagctggag gagaaggcta tggaagagct caaggagatc atacagcaag gaccagactg     2100

gcttgagctc tctgagatga ccgagcagcc agactatgac ctggagacct ttgtgaacaa     2160

agcggaatct gctctggccc agcaagccaa gcatttctca gccctgcgag atgtcatcaa     2220

ggccttgcgc ctggccatgc agctggaaga gcaggctagc agacaaataa gcagcaagaa     2280

acggccccag tgacgactgc aaataaaaat ctgtttggtt tgacacccag cctcttccct     2340

ggccctcccc agagaacttt gggtacctgg tgggtctagg cagggtctga gctgggacag     2400

gttctggtaa atgccaagta tgggggcatc tgggcccagg gcagctgggg agggggtcag     2460

agtgacatgg gacactcctt ttctgttcct cagttgtcgc cctcacgaga ggaaggagct     2520

cttagttacc cttttgtgtt gcccttcttt ccatcaaggg gaatgttctc agcatagagc     2580

tttctccgca gcatcctgcc tgcgtggact ggctgctaat ggagagctcc ctggggttgt     2640

cctggctctg gggagagaga cggagccttt agtacagcta tctgctggct ctaaaccttc     2700

tacgcctttg ggccgagcac tgaatgtctt gtactttaaa aaaatgtttc tgagacctct     2760

ttctacttta ctgtctccct agagatccta gaggatccct actgttttct gttttatgtg     2820

tttatacatt gtatgtaaca ataaagagaa aaaataaatc agctgtttaa gtgtgtggaa     2880

aaaaaaaaaa aaaaaa                                                     2896


<210>  159
<211>  6275
<212>  DNA
<213>  homo sapiens

<400>  159
ggaatgcggc tgcgcactgg gcgctctcgc ccgagaagcc gcagtctcga gagcgtcaac       60

gaggtgtttc ggtagtctct ggccatcctt tctgcgcacc cggtgtcgct gggctgcacc      120

ccgggcgggg acgtccgccg ggcacgggag ggggccaaga tgccgatcaa taaatcagag      180

aagccagaaa gctgcgataa tgtgaaggtt gttgttaggt gccggcccct caatgagaga      240

gagaaatcaa tgtgctacaa acaggctgtc agtgtggatg agatgagggg aactatcact      300

gtacataaga ctgattcttc caatgaacct ccaaagacat ttacttttga tactgttttt      360

ggaccagaga gtaaacaact tgatgtttat aacttaactg caagacctat tattgattct      420

gtacttgaag gctacaatgg gactattttt gcatatggac aaaccggaac aggcaaaact      480

tttaccatgg aaggtgttcg agctattcct gaacttagag gaataattcc caattcattt      540

gctcacatat ttggtcatat tgcaaaagcg gagggtgata caagattttt ggttcgagtg      600

tcttatttgg aaatatataa tgaagaagtt cgtgaccttt tgggcaagga tcagacacaa      660

aggttagagg ttaaagaaag acctgatgtg ggagtttata tcaaagattt atcagcttat      720

gtggtaaata atgctgatga tatggataga attatgacgc taggccacaa aaatcgttct      780

gttggtgcaa ctaatatgaa cgaacatagt tcccgttccc atgccatctt tacaattact      840

atagaatgca gtgaaaaagg cattgatggt aacatgcatg tcaggatggg gaagctccat      900

cttgtagatc ttgctggttc agaaagacag gcaaaaactg gagctactgg acagcgccta      960

aaggaagcta caaaaatcaa tctttcactt tccacccttg gtaatgtaat ttctgccttg     1020

gttgatggaa aaagcactca tgtgccttat cgtaactcta aactgactcg tcttcttcag     1080

gattccttag gaggaaattc aaaaaccatg atgtgtgcaa atattgggcc agcagattac     1140

aattatgatg aaactatcag tacattacgg tatgccaatc gtgctaagaa tattaaaaat     1200

aaagctagaa ttaatgaaga tccaaaggat gctttgctgc gtcagttcca gaaagaaata     1260

gaagaactga aaaagaagct tgaagaagga gaagaaatat caggctctga tatcagtggg     1320

tcagaggaag atgatgatga agagggtgag gttggagaag atggagagaa aaggaaaaaa     1380

agaaggggaa aaaagaaagt ctccccagac aagatgattg aaatgcaagc aaaaattgat     1440

gaggagagaa aagcacttga aacaaagctc gacatggaag aagaagaaag aaacaaggct     1500

agagctgaat tagagaaacg ggaaaaagat cttcttaaag cccaacaaga gcatcagtct     1560

ttgctggaaa aattatctgc cctggaaaag aaggtaattg ttggtggggt tgacttgttg     1620

gccaaagctg aggaacaaga gaaacttctt gaagaatcta acatggaact ggaagaaagg     1680

aggaaaagag cagagcaact tcgcagagaa cttgaggaaa aagagcaaga acgcttggat     1740

attgaagaaa aatataccag tttgcaagag gaagcacagg gaaagaccaa gaagttaaag     1800

aaagtttgga ctatgctgat ggctgcaaag tcagagatgg ctgatctcca acaagaacat     1860

cagagggaaa ttgaaggcct actggagaac attcggcaac ttagccggga gcttcgactt     1920

cagatgctta ttattgataa ctttatacct cgggattatc aggaaatgat tgaaaactat     1980

gtccattgga atgaagacat aggagaatgg cagctaaaat gtgttgctta tacaggaaat     2040

aacatgagga agcaaacccc agtacctgat aaaaaggaga aagatccctt tgaggtggac     2100

ctttctcacg tgtatcttgc ctatactgag gagagtctgc gtcagtcttt gatgaaacta     2160

gaaagaccac gaacttcaaa ggggaaagca aggccaaaga cagggagaag aaagcgttct     2220

gcaaagcctg aaactgtaat tgactcttta ctgcagtaaa tgttacagac ttaaagtcac     2280

aataaaaatt agtgatattc tcatgcctgg acaaaatctt taattaaaac agtgaagact     2340

tctctataat ttcaattaat ggaagttgta gatcaatgaa taagactgga aataataatt     2400

tgcttaagaa cttttagtct acatatatta atataacatt aaaattgtac aactggtgat     2460

tgttcaaatt gttgtactac tactcttcaa ttgtactgtg cagggaagtt gggggaacag     2520

ttcatactat agagagttac agtttagatg tatgtgtaaa tcgattagct atttatccaa     2580

ctactgtata tttaggtaac tagaatttca aaatagaaaa aaaaaaactg tgtcctgttt     2640

tgcacataga aagaagcaga tcagattgtc ctatgttgcg ctgttatata tgaatgtttg     2700

gactgtacat ctaaagaatg attccgtcct aacacccacc cagcctgttt gaacacattc     2760

taattgtcta acatttgttg cattttaagt atgagatgac tgatcttatg aatgttttgt     2820

agaaaatgtt ataatttaac agtctttgcg agtatacatg ttttttaaca agttgaaaat     2880

gtttcatctg aacctttcct aacttttttt tgccagtttg agttcaaatc aaatacacct     2940

taagttctgg tttcatgttc tcttgaaaca ttgaattgta cgtaaatata aaggatctac     3000

tgttgcggaa aattaagaag ctaaatactg ctcagttatc tttgcctgcg tgtatatttt     3060

taaaaattca ctctgaagtg ttatggatgc ttttctttga gttctaaatt ttggtgggaa     3120

ttactttatg tctcccagtt aagaagagtc tccattttcc agaaaataca gctaagcaag     3180

aaaaatatct tttaaatact ttgcctttaa aacacttttt tattttgttt ttctatttta     3240

aaaataaaat attattttct gaatttcttc tattgggtaa tccagttaga ccatattcct     3300

ctacaaataa aaactatgtt gatttcatag taaagtaagt tgtaatagag ataattattt     3360

ttttctgttg ttagctgctt atgaaacttt tattgtattt ttttaaagtt atgctactcc     3420

tggccgggca tggtggctca cgcctgtaat cccagcactt tgggaggccg aggcacgtgg     3480

atcacttgat gtcaggagtt cgagaccagc ctggctaaca tggtgaaacc ctgtctccag     3540

tacaaataca ataattagct gggtgtggtg gcgcacacct gtaatcccag ctacttggga     3600

ggctgaggca ggagaatcac ttgaacctgg gaggcggagg ttgcagtgag ctgagatggc     3660

atcactgcac tccagcctgg gtgacagggt gacactccac ctcaaaaaat aaaaataaaa     3720

taaaaataaa gttatgctac tcctaaacca cttaatatat gttttgtggt tttcaaaatt     3780

atgtaatcag ccctgaaaca cattggttga aaatattttg agactttata agttagtatt     3840

tattaaatta atattatttt aataagtttt gttaaatcct agtttaaatg acaaagctgt     3900

gtatagagta ggggtgagtg aaggtggagt actcttgagg tggcgataaa aatgtaccca     3960

taaatttaaa gtccattctg taattggaat actgaatgtc ctgtgtgtgg tgaacatttt     4020

ctaggtgatt agaattgcat ttcactggct gcatttgttt gtggtatgta agatagctag     4080

aaatttatta cttaactctg tggggcattg tttagatact gtgaagagtt gaggtaaata     4140

tgtgtcttgt aaaagctttg tgtgatcaga atattttggt aattataaaa tgtttttgat     4200

gatacacatt taactctgtt agtaattact ctaaagaaat cttaatttta ccagtttaaa     4260

aaaaacgctt ctttttaaaa gttcatgttt ctaaccttta acaattcagt taataggaaa     4320

ggagtaactt ttaaatcaag ctttaaaaca tggaaattta agccagtatg ttagatattt     4380

tttctatccc accctaccat gataataaaa ataaatctat aaaaagtcaa aataaaaagc     4440

cgatctataa aaagtcaatt gagaagttct aaaagcaggc tactatagca ggggtgtttg     4500

ttttttgttt ggagacggag tctggctcta ttacctaggc tggagtgcag tgggacaatc     4560

tcggctcact gtaacctctg tctcttcagc ctcctgagtt gctggaacta cagctgtatg     4620

ccatcatgct cggctaattt ttgtattttt ttgtagagat ggggttttgc catgttgccc     4680

gggcctgtct tgaactccta gagcttaagt gatccacccg cctcaggctc ccgaagtgct     4740

gggattacag gcatgattat aggcctgagc caccacaccc cgcctactat agcagttttt     4800

taaaaaaagc attatgttaa aactgattat accagatgga cattaaatat ccatctcaga     4860

aataccaaaa tttgatacat aagcctggcc tgaatatctt tttttttttt ttgagacgga     4920

gtcttactct gtcgcccagg ctggagtgca gtggcgcgat ctcggctcac tgcaacctct     4980

gcctcctggg ttcaagggat tctcctgcct cagcctcttg agtagctggg attacaggtt     5040

tgcgccacca cacccagcta atttttgtat ttttttttta gtagagaccg ggtttcacca     5100

tgttggccag gctggtctca cctgactttg tgatccgccc gcctcagcct cccaaagtgc     5160

tgggattaca ggtgtgagcc accacgcctg gcctcaagcc tggtctgaat atctatatgc     5220

aaatatggga cactgacttc agagctattc atttagctcc agtcatagca attctgtagt     5280

ttcctcacat ttactgtgtc tttgtccaca aatgaaatat gttgtaaggt cagtgttaat     5340

ttcgtgagac gatatagatg aacacacttg ctcatttttt gaaataaata tgcagattta     5400

aaatgagtgg cacatatata taaataggtt attgaatggg tattctcttt tccctttaat     5460

ttaaaaagtg atatttattt attaaaagga gcattggtag aattattggt ttatagtatc     5520

ttctttaata atccttacaa ttacatatac taataggatg ttaaaattat catcgtgttt     5580

cctatttgtg tttagattct tataaagcat gagatgagta atcaagggaa gggtcgcatc     5640

tccatgtttg ccccatgaat agaatccatt tgacaagcca tttcatttcc tttctggaga     5700

aagggagttg tttttttttt ctttttacag caaaaattta aggttttatt gggggagggg     5760

gtggtgctac ttcctctgta acatgttttt aaaactatga ttatggtttt tggttgtttt     5820

ttgttttgtt tgtttccttt tagtctgttt ttaatatcct tccccttaac tcttaaggaa     5880

agtcttcttt cctacagggc tgtgaattaa ggaatgggta gcgtttacat ttaagtacac     5940

caatgtctgc ccaatttcct aatgtataca tttgttttat tttaaattat tttttgttct     6000

taaaaatact agaagaaaac atagatgttt ctagtgcctt tgaacttata ctgtagtctg     6060

actaatttaa tgaataactt cagtagcatt actataatac tgtatgctgg ccaaaattac     6120

aaattacagt ttgttgcatc agtttcaaaa gccatgcttt cattgtattt tatgtataaa     6180

ttgtatttgt tcaagttgta tatattggta ttgtatgtat acatgcagca tggttaaata     6240

agaataaaaa tcttttacct aatgccaaaa aaaaa                                6275


<210>  160
<211>  4155
<212>  DNA
<213>  homo sapiens

<400>  160
gcctgctcca agggaaggat caggagagaa gaaacgcaaa tcccagaacc gtgccaacat       60

ataaaacccc acattaaggg ttgtacagtg cactgggatt tctcaagtca cccgcttggt      120

cctcttccaa gtatacttta cttcctttca ttcctctcta aaactttttt aaaaactttc      180

actcctgctc taaaagttat cttggtttct tactctacct tatgcccctt gggcgaattt      240

tttcctctga ggagggaaga atagagttgc tgctgcagac acatcagatt ccctactggt      300

aacagctgga gtgcgtcacc tctgacaaaa ttctggggac gctgggaaca ctgaatcaac      360

atgggcaatg agaacagcac ctcggacaac cagaggactt tatcagctca gactccaagg      420

tccgcgcagc cacccgggaa cagtcagaat ataaaaagga agcagcagga cacgcccgga      480

agccctgacc acagagacgc gtccagttca cctgtggcag atgatatcat ccagcccgct      540

gcccccgcag acctggaaag cccaacctta gctgcctctt cctaccacgg tgatgttgtt      600

ggccaggtct ctacggatct gatagcccag aggagttccg attctgaaga ggcatttgag      660

accccggagt caacgacccc tgtcaaagct ccgccagctc cacccccacc accccccgaa      720

gtcatcccag aacccgaggt cagcacacag ccacccccgg aagaaccagg atgtggttct      780

gagacagtcc ctgtccctga tggcccacgg agcgactcgg tggaaggaag tcccttccgt      840

cccccgtcac actccttctc tgccgtcttc gatgaagaca agccgatagc cagcagtggg      900

acttacaact tggactttga caacattgag cttgtggata cctttcagac cttggagcct      960

cgtgcctcag acgctaagaa tcaggagggc aaagtgaaca cacggaggaa gtccacggat     1020

tccgtcccca tctctaagtc tacactgtcc cggtcgctca gcctgcaagc cagtgacttt     1080

gatggtgctt cttcctcagg caatcccgag gccgtggccc ttgccccaga tgcatatagc     1140

acgggttcca gcagtgcttc tagtaccctt aagcgaacta aaaaaccgag gccgccttcc     1200

ttaaaaaaga aacagaccac caagaaaccc acagagaccc ccccagtgaa ggagacgcaa     1260

caggagccag atgaagagag ccttgtcccc agtggggaga atctagcatc tgagacgaaa     1320

acggaatctg ccaagacgga aggtcctagc ccagccttat tggaggagac gccccttgag     1380

cccgctgtgg ggcccaaagc tgcctgccct ctggactcag agagtgcaga aggggttgtc     1440

cccccggctt ctggaggtgg cagagtgcag aactcacccc ctgtcgggag gaaaacgctg     1500

cctcttacca cggccccgga ggcaggggag gtaaccccat cggatagcgg ggggcaagag     1560

gactctccag ccaaagggct ctccgtaagg ctggagtttg actattctga ggacaagagt     1620

agttgggaca accagcagga aaacccccct cctaccaaaa agataggcaa aaagccagtt     1680

gccaaaatgc ccctgaggag gccaaagatg aaaaagacac ccgagaaact tgacaacact     1740

cctgcctcac ctcccagatc ccctgctgaa cccaatgaca tccccattgc taaaggtact     1800

tacacctttg atattgacaa gtgggatgac cccaatttta accctttttc ttccacctca     1860

aaaatgcagg agtctcccaa actgccccaa caatcataca actttgaccc agacacctgt     1920

gatgagtccg ttgacccctt taagacatcc tctaagaccc ccagctcacc ttctaaatcc     1980

ccagcctcct ttgagatccc agccagtgct atggaagcca atggagtgga cggggatggg     2040

ctaaacaagc ccgccaagaa gaagaagacg cccctaaaga ctgacacatt tagggtgaaa     2100

aagtcgccaa aacggtctcc tctctctgat ccaccttccc aggaccccac cccagctgct     2160

acaccagaaa caccaccagt gatctctgcg gtggtccacg ccacagatga ggaaaagctg     2220

gcggtcacca accagaagtg gacgtgcatg acagtggacc tagaggctga caaacaggac     2280

tacccgcagc cctcggacct gtccaccttt gtaaacgaga ccaaattcag ttcacccact     2340

gaggagttgg attacagaaa ctcctatgaa attgaatata tggagaaaat tggctcctcc     2400

ttacctcagg acgacgatgc cccgaagaag caggccttgt accttatgtt tgacacttct     2460

caggagagcc ctgtcaagtc atctcccgtc cgcatgtcag agtccccgac gccgtgttca     2520

gggtcaagtt ttgaagagac tgaagccctt gtgaacactg ctgcgaaaaa ccagcatcct     2580

gtcccacgag gactggcccc taaccaagag tcacacttgc aggtgccaga gaaatcctcc     2640

cagaaggagc tggaggccat gggcttgggc accccttcag aagcgattga aattacagct     2700

cccgagggct cctttgcctc tgctgacgcc ctcctcagca ggctagctca ccccgtctct     2760

ctctgtggtg cacttgacta tctggagccc gacttagcag aaaagaaccc cccactattc     2820

gctcagaaac tccaggagga gttagagttt gccatcatgc ggatagaagc cctgaagctg     2880

gccaggcaga ttgctttggc ttcccgcagc caccaggatg ccaagagaga ggctgctcac     2940

ccaacagacg tctccatctc caaaacagcc ttgtactccc gcatcgggac cgctgaggtg     3000

gagaaacctg caggccttct gttccagcag cccgacctgg actctgccct ccagatcgcc     3060

agagcagaga tcataaccaa ggagagagag gtctcagaat ggaaagataa atatgaagaa     3120

agcaggcggg aagtgatgga aatgaggaaa atagtggccg agtatgagaa gaccatcgct     3180

cagatgatag aggacgaaca gagagagaag tcagtctccc accagacggt gcagcagctg     3240

gttctggaga aggagcaagc cctggccgac ctgaactccg tggagaagtc tctggccgac     3300

ctcttcagaa gatatgagaa gatgaaggag gtcctagaag gcttccgcaa gaatgaagag     3360

gtgttgaaga gatgtgcgca ggagtacctg tcccgggtga agaaggagga gcagaggtac     3420

caggccctga aggtgcacgc ggaggagaaa ctggacaggg ccaatgctga gattgctcag     3480

gttcgaggca aggcccagca ggagcaagcc gcccaccagg ccagcctgcg gaaggagcag     3540

ctgcgagtgg acgccctgga aaggacgctg gagcagaaga ataaagaaat agaagaactc     3600

accaagattt gtgacgaact gattgccaaa atggggaaaa gctaactctg aaccgaatgt     3660

tttggactta actgttgcgt gcaatatgac cgtcggcaca ctgctgttcc tccagttcca     3720

tggacaggtt ctgttttcac tttttcgtat gcactactgt atttcctttc taaataaaat     3780

tgatttgatt gtatgcagta ctaaggagac tatcagaatt tcttgctatt ggtttgcatt     3840

ttcctagtat aattcatagc aagttgacct cagagttcct gtatcaggga gattgtctga     3900

ttctctaata aaagacacat tgctgacctt ggccttgccc tttgtacaca agttcccagg     3960

gtgagcagct tttggattta atatgaacat gtacagcgtg catagggact cttgccttaa     4020

ggagtgtaaa cttgatctgc atttgctgat ttgtttttaa aaaaacaaga aatgcatgtt     4080

tcaaataaaa ttctctattg taaataaaat tttttctttg gatcttggca ataaaaaaaa     4140

aaaaaaaaaa aaaaa                                                      4155


<210>  161
<211>  5049
<212>  DNA
<213>  homo sapiens

<400>  161
acagacaaga tgtcggcgga tggtagcttc gagcccttgc ggagaggagc atctctgtga       60

cagaagcttg tcgacggcgg cttctaggag ctagtcgaag gagcgaggtt gaggcgggca      120

gcgacccgtc aggtcgctca cctgggcacc ggccagctgc gagacgtgac ttggggaccg      180

caggggagtg gagagtgtga ggtgccaaag actagtaatg ccccgtatcc ccctaggaag      240

ccgggaagcc aagctccgcg ggaccgcttc atgccgctga ctggtgtaga gcccgccaga      300

atgaacagga agaaaggaga caagggcttt gaaagcccaa ggccatataa attaacccat      360

caggtcgtct gcatcaacaa cataaatttc cagagaaaat ctgttgtggg atttgtggaa      420

ctgactatat ttcccacagt tgcaaacttg aatagaatca agttgaacag caaacagtgt      480

agaatatacc gagtaaggat caatgattta gaggctgctt ttatttataa tgacccaacc      540

ttggaagttt gtcacagtga atcaaaacag agaaacctca attatttttc caatgcttat      600

gcagctgcag ttagtgctgt ggaccctgat gcaggaaatg gagaactttg cattaaggtt      660

ccatcagagc tatggaaaca cgttgatgag ttaaaggtcc tgaagataca catcaatttt      720

tctttggatc agcccaaagg aggtcttcat tttgtggtac ccagtgtaga gggaagtatg      780

gcagagagag gtgctcatgt tttctcttgt gggtatcaaa attctacaag attttggttc      840

ccttgtgttg attcatactc tgaattgtgt acatggaaat tagaatttac agtagatgct      900

gcaatggttg ctgtttctaa tggcgatttg gtggagacag tgtatactca tgatatgagg      960

aagaaaactt tccattatat gcttaccatt cctacagcag cgtcaaatat ctccttggcc     1020

attggaccat ttgaaatact ggtagatcca tacatgcatg aggttactca tttttgtttg     1080

ccccaacttc ttccattgct gaaacatacc acatcatacc ttcatgaagt ctttgaattt     1140

tatgaagaaa ttcttacatg tcgttaccca tactcctgtt ttaagactgt cttcattgat     1200

gaggcttatg ttgaagtggc tgcttatgct tccatgagca tttttagcac aaatctttta     1260

cacagtgcca tgattataga tgagacacct ttgactagaa ggtgtttagc ccaatccttg     1320

gcccagcagt tttttggttg tttcatatct agaatgtctt ggtctgatga atgggtgctg     1380

aagggaattt caggctatat ctatggactt tggatgaaaa aaacttttgg tgttaatgag     1440

taccgccatt ggattaaaga ggagctagac aaaatagtgg catatgaact aaaaactggt     1500

ggggttttac tacatcccat atttggtgga ggaaaagaga aggataatcc ggcttcccat     1560

ctacactttt caataaagca tccacataca ctgtcctggg aatactacac tatgtttcag     1620

tgtaaagccc accttgtgat gagattgatt gaaaatagga tcagtatgga atttatgcta     1680

caagttttca ataaactgct aagtctggct agtactgctt catctcagaa gttccagtca     1740

catatgtgga gtcagatgtt ggtttccaca tctgggtttt tgaaatccat ttcaaatgtc     1800

tctggcaaag atattcagcc gttaataaag cagtgggtag atcagagtgg agtggtaaaa     1860

ttttatggaa gttttgcatt taatagaaaa cgaaatgtct tggaactgga aataaaacag     1920

gactatacat ctcctggaac tcagaaatac gtgggaccac ttaaagtgac agtgcaggag     1980

ttagatggat ccttcaatca tacactgcaa attgaagaaa acagccttaa acatgatata     2040

ccctgccatt ccaaaagtag aaggaataaa aagaaaaaaa tcccactgat gaatggagaa     2100

gaagttgata tggatctttc tgcaatggat gctgattccc ctttgctgtg gataaggata     2160

gacccagata tgtcagtatt gaggaaggta gaatttgagc aagctgattt tatgtggcag     2220

tatcagctcc gctatgagag agatgttgtt gcacagcagg aatccatttt ggctttggaa     2280

aaattcccta ctccagcatc tcggcttgca ctcactgata tattagaaca agagcagtgt     2340

ttctacagag taagaatgtc agcttgcttc tgtcttgcaa agattgcaaa ttcaatggtg     2400

agcacatgga caggaccacc agccatgaag tcactcttca ctaggatgtt ttgttgtaaa     2460

agttgtccaa acattgtgaa aacaaacaac tttatgagct ttcaaagcta ttttctacag     2520

aagactatgc cagttgcaat ggctttatta agagatgttc ataatctttg tcctaaagaa     2580

gtcttaacat ttattttaga cttaatcaag tacaatgaca acaggaaaaa taagttttca     2640

gataactatt atcgtgcaga aatgattgat gccctggcca actctgttac acctgcagtc     2700

agtgtgaata atgaagttag aactttggat aacttaaatc ctgatgtgcg actcattctt     2760

gaagaaatca ccagattttt gaatatggaa aaacttcttc cgagttacag gcataccatc     2820

actgtcagtt gtttgagagc catacgggta cttcagaaga acggacatgt gccaagtgat     2880

ccagctcttt ttaaatctta tgctgaatat ggccactttg tggacattag gatagcagct     2940

ttggaagcag ttgttgatta tactaaagtg gacagaagtt atgaagaact gcaatggcta     3000

cttaatatga ttcagaatga ccctgtaccc tatgtaaggc ataagattct caacatgttg     3060

actaagaacc caccatttac taagaacatg gagtctccct tatgcaatga agccctggta     3120

gatcaacttt ggaaacttat gaattctggt acttcacatg actggaggtt acggtgtggt     3180

gctgtggact tgtacttcac actttttggc ctcagtagac cttcctgttt acccttgcca     3240

gagcttgggt tggttcttaa tctaaaggag aaaaaagctg tcttgaatcc taccataatt     3300

ccagagtcag tagcaggcaa ccaagaagct gcaaataatc caagcagtca cccacagcta     3360

gttggatttc agaacccttt ttccagttct caagatgagg aggagattga tatggatact     3420

gttcatgata gccaggcctt catttcccat catttaaaca tgcttgaaag gccgtcaact     3480

ccagggctct cgaaatatcg gccagctagc tcccgatctg ctttaatacc ccagcactca     3540

gcaggctgtg acagcacacc caccacaaaa ccccagtgga gtttggaact tgcacggaag     3600

ggaacaggta aagaacaagc acctttggag atgagtatgc atccagcggc aagcgctcca     3660

ctctcagtct ttactaagga atctacagcc tccaaacaca gtgaccacca tcaccaccat     3720

caccatgagc acaagaaaaa gaagaagaag cataaacata agcacaaaca caagcataag     3780

catgacagta aagaaaagga caaggagcct ttcactttct ccagccctgc cagtggcagg     3840

tctattcgtt ctccttccct ttcagactga gaaggggaca aaaagacctt tcctttcatg     3900

tccagaagaa tgtatgtaac taaagctttg tcctctgtga agaattataa aagggagggg     3960

ggaaaggatt cgcctctcct acagaaattc tgaattcatt taagttctaa gcatttgatt     4020

tatgttattt atacagttgg gatctaatta ggaaaatgtg ttttgtagtt ctggataaac     4080

tatttcatcc gctgtttcct ccccaaaaca cacacacaga gcaaactccc tttcataaaa     4140

gccctcatat ccactggcag tccccgttcg catcatggtc tccatgtgta ccgccaaagt     4200

caattatgtt tgaaagcctt tggtggatgt tatggggcaa agttatgatt tacacagaag     4260

caactgccaa atctgtggtg caaccactat ctccagtgaa atattgtata acaccatttg     4320

gaactactga aaagacagtg gcttttctac agtactcttc cttattgcac catttttgta     4380

ttaacgtaga aactaagcat cagaatttat gaacaaagaa tatgttattt ttccttttgc     4440

tctaaaatac tgagatttgg ggaagcaatt cttttttaaa aaaattttga ataactatct     4500

tttgataaca cattcggcgg ttacgatgtt ggaatttagc agaactatca aatccaaaat     4560

tattttcaaa tcaagatgtt taaattataa gtttttttgt tttgttttcc agtaagtata     4620

aatgaaaata ttcatatgta aaatatgttt tgcttaatgt ggacaattta cacacccaac     4680

acatactgtt tccaaaatta tttctatatg acacaaagta tgataccttt aaaaaggtga     4740

gcttatatat tgtttattaa cctggaaata gacaatttgg ctctcatacc ataagcattt     4800

aaaaacatat gaaatatttt gatttcttta tatggtggtg tgtttttatt tctgaatttt     4860

ccatgtgctt taatatttgt ttaagaatat tttttatatc tgttcaattt ttatcattcc     4920

ccttatcatt agaaagtttg acaaaaatac ttgaatcttg gacctctaaa tatactttta     4980

gttgtgttta acttgtttaa taaataactt tttaagttga aaaaaaaaaa aaaaaaaaaa     5040

aaaaaaaaa                                                             5049


<210>  162
<211>  4359
<212>  DNA
<213>  homo sapiens

<400>  162
gggggccccg ccgccccagc agcccaggac agccccctct ccccgccccc agccccctcc       60

cccggcgcgg ccatggatgt gaccagcagc tcgggcggcg gcggcgaccc ccggcagatc      120

gaggagacca agccgctgct ggggggcgac gtgtcggccc ccgaaggcac gaagatgggc      180

gccgtgccct gccgccgggc tcttctgctt tgcaacggga tgaggtacaa actgctgcag      240

gagggcgaca ttcaggtctg tgtcatccgg cacccgcgga cctttctcag caagatcctc      300

acctcgaaat tcctgaggcg ctgggagccg caccacctaa cgctggccga caacagcctg      360

gcgtccgcca cgccaactgg gtacatggaa aactcagtct cctacagcgc aattgaagac      420

gttcagctgc tgtcctggga gaatgccccg aagtactgtt tacagctcac gattcctggg      480

ggaactgtct tactgcaggc tgccaatagc tacctgcgag accagtggtt ccattctctg      540

caatggaaga aaaagattta caaatataag aaagtgctga gtaacccaag ccgctgggaa      600

gttgtcttga aagagatccg gaccctggtg gacatggccc tgacatcccc cctgcaggat      660

gactccatca accaggcccc actggaaatc gtctcgaaac tgctctcaga gaacacaaac      720

ttgaccaccc aggagcatga aaacatcatt gtggcaatcg ctcctttgct ggaaaacaac      780

cacccaccac cagatctctg tgaattcttt tgcaagcact gcagagagcg gccccggtcc      840

atggtggtca tcgaggtgtt cacccccgtg gtgcagcgaa tcctcaagca taacatggac      900

tttgggaagt gcccgcgact gaggctgttt actcaggagt acatccttgc cttgaacgag      960

ctcaacgcgg ggatggaagt ggtgaagaag ttcattcaga gcatgcacgg ccccacaggg     1020

cactgccccc acccccgggt cctgcccaac ctggtggccg tgtgcctggc tgccatctac     1080

tcctgctatg aagagttcat caacagccgc gacaattccc caagcctgaa ggaaatccgg     1140

aacggctgcc agcagccgtg cgaccggaag cccactttac ctctgcgcct tctgcacccc     1200

agcccggacc tggtgtctca ggaagccacg ctgtctgagg cccggctcaa gtcggtggtc     1260

gtggcctcca gtgagatcca cgtggaggtg gaacgcacca gcactgccaa gccggcgctg     1320

acggccagcg caggcaacga cagcgagccc aacctcatcg actgcctcat ggtcagcccc     1380

gcctgcagca ccatgagcat cgagctgggc ccccaggccg accgcacgct cggctgctac     1440

gtggaaatcc tcaagctgct gtcagactat gatgactgga gaccgtctct ggccagtttg     1500

cttcaaccca ttccattccc caaagaagct ctcgcacatg agaagttcac caaggaactg     1560

aagtacgtga ttcagaggtt cgccgaagac cccaggcaag aggtccactc atgcctgctg     1620

agcgtgcggg ccggcaaaga tggctggttc cagctctaca gccccggagg ggtggcctgc     1680

gacgatgacg gggagctgtt cgccagcatg gtgcacatcc tcatgggctc ctgttacaag     1740

accaaaaaat tcctgctctc cctggcagaa aacaagctgg gtccctgcat gctcctggca     1800

ctgaggggga accagaccat ggtggagatc ctgtgcttga tgctggaata caacatcatc     1860

gacaacaacg acacccaact gcagatcatc tcaaccctgg agagcacaga cgtggggaag     1920

cgcatgtacg agcagctgtg tgaccggcag cgggagctga aggagctgca aaggaaaggc     1980

gggcccacca ggctaacact gccctccaag tccacagacg ctgacttggc tcgtttgctg     2040

agctccggct ccttcggaaa cctggagaac ctcagtttgg ccttcaccaa tgtaaccagt     2100

gcctgcgccg agcacctcat caaactgcct tcgctcaagc agctgaacct gtggtccact     2160

cagtttggag acgctggcct tcggctcctg tcggaacacc tcaccatgct ccaggtgctg     2220

aacctgtgcg agaccccggt cacagacgct ggcctgctgg ccctgagctc catgaagagt     2280

ctctgcagtt taaacatgaa cagcaccaag ctctcagctg acacctacga agatctgaag     2340

gccaagcttc ccaatttgaa ggaagtggac gtccgctaca ccgaagcctg gtgaagctcc     2400

cagctcaagg caggaagacg tttgcaaccg cgacaaaata actcttgact aacagccgca     2460

gagcagccgg tcctggggtc ccaccctggt gccctggctg tgagatagat ggggagtctt     2520

tctgggggcg gaggggggag ggggtgggga gggggcccac aagcacgccc agcccccgcc     2580

gaattctttt agcttcgtaa ttggaacctt tgacctgatc taaagtggac tttgtagcaa     2640

caagaggagc atcagcgggt cggggagggg tttgggggtg ggctgggggg tgggggaccc     2700

tttgtggatt ttctttgcct ttgtgtttga tgccgtcgtg tgggaaaagt caactccgat     2760

gccaccattg cgggccggac gaaggatgct ttcttcctag aggctccgag ctgagctgcg     2820

aactcgcccc ccgcccttgg gacaagaaga cccagtcaca tcactgcacc cgtcctgtgt     2880

cctcaccatt gctatgcaaa gtgattcttg ttgtacataa gatttaaata atgcacctat     2940

ttaagacatg ttgacaaatt gcgggtctgg gacccgcctc ttatttatga agtctttgac     3000

cgtccccccc gcccgacccc accgccctcc cgcccccacc tggcgtgtag tactgtataa     3060

accagtcagc tgtcgggtta gtggtagtat tattgttatt tttttaaagg aaacaaacag     3120

acaacaaaaa gaagaaaaaa aaaaagaacc tccttggaaa aattaattgc tttttcgtaa     3180

tggattctct atgctaatgc tctctcgtct gtctgtctgt ctgcccactc ccccacccac     3240

cactgtgcgt ttctgatttc caaatgtctc caactccctc acgaggtggg gctcaggctg     3300

gaggaggagg gattaagatc cccttgctcc actaaggccc aagctctttc tctcggcacc     3360

ttttagactt gaatgggagg ctgctaaccc gccctctcca gtccaccccg gtaaaagagc     3420

tgttccccac ccccagggag ctcctgtccc tgtcagcctt tgctgtcccc tgtccccaac     3480

ggagactctg tcacccctgg gctccccctg ccatcgtgtg cttcacgtgg ccccatgcat     3540

gcccgcctct ctgcatggtc tcttgggaaa agagagatgt gtcgcctccg ccagtccgac     3600

tgccctcccc accccacccc cgccaccccc cacatgtgac cactgcaacg aagacactcc     3660

ttctgtcccc acctgctccg aagacaaacc aacctccgtt tcttttataa acagtcggct     3720

ttttcttaat aagccctcac tgtacagaac agcccgttga tggtttattt ggggtccccc     3780

tctcccccca gccctttttt ctgttggttt agcacaaata cttccctcct ccggcacctc     3840

caaacctacc ccacagtcag tgtacttgtt ttatatatat ttaatcttat tcaatggaaa     3900

ccatgctttt gtcgttttat actttgctag gtagacttta ttaccccccc actatgccct     3960

cattttttta aaaaaggaaa aaaaaaagaa actgggttcc agtcttaatt cattttccgt     4020

gccaggtttt atttcgtgtg tgtgtgagtg tgttctgttt tgtgttttgt tttttgttgt     4080

tgtttttagt tgtttggttt tcttttcttt cccccctccg gtcccatact tcacagcact     4140

ctggtgcggg aagaagcaga agcaaaaaaa ataaaaataa aaaaataaat aaaaataaaa     4200

aaaataaaaa aggaaaaaaa aaaaagaaga aacaagacat gccacctttc ccctcgcact     4260

gttgcttttc ctgatggtta atactactgt cacgtagctg tgtacaaaga gatgtgaaat     4320

actttcaggc aaaaataaac tgtaagtgac tcatcaaaa                            4359


<210>  163
<211>  3430
<212>  DNA
<213>  homo sapiens

<400>  163
agcggaccga gccgcagccg cagccgggcg gcgggcgaga ggcggcggcg gcgggcgggc       60

cgcgggcagt cagtcgggcg gcggcggcgg cggcggcggc ggcgatgcgg cggccccgct      120

gagtccgccc gctcctggcg ccgggagcca gccgcgcgag gcggcccggg ccgggcggca      180

gcatgcggag cggcgaggag ctggacggct tcgagggcga ggcctcgagc acctccatga      240

tctcgggcgc cagcagcccg taccagccca ccaccgagcc ggtgagccag cgccgcgggc      300

tggccggcct gcgctgcgac cccgactacc tgcgcggcgc gctcggccgc ctcaaggtcg      360

cccaagtgat cttggccctg attgcattca tctgcataga gaccatcatg gcatgctccc      420

cgtgtgaagg cctctacttt tttgagtttg tgagctgcag tgcgtttgtg gtgactggcg      480

tcttgctgat tatgttcagt ctcaacctgc acatgaggat cccccagatc aactggaatc      540

tgacagattt ggtcaacact ggactcagcg ctttcctttt ctttattgct tcaatcgtac      600

tggctgcttt aaaccataga gccggagcag aaattgctgc cgtgatattt ggcttcttgg      660

cgactgcggc atatgcagtg aacacattcc tggcagtgca gaaatggaga gtcagcgtcc      720

gccagcagag caccaatgac tacatccgag cccgcacgga gtccagggat gtggacagtc      780

gccctgagat ccagcgcctg gacacttttt cctactccac aaacgtaaca gtaaggaaaa      840

aatcacccac aaacctgctg agtttgaatc actggcaact tgcctagaaa agttcagatg      900

atgggtcctt gaactgtgta tctatttcat agggtaagtt tgttgtctat gtttgttttt      960

ttatgctgag gctttaattc aggtgacttg ctatctagac acctggggtg gcgtgttttc     1020

tttgggatgc ataatacaca aaggccaggg agcctttggc ttggaccccc agggagctat     1080

tgaaactttt aaagtttgag tttaggagta agaacatatc tcagaccacc ttagtcagct     1140

ttgctgatgg gatttagggc caggtcagag tttcttttca taactgcctg aaaagagaga     1200

tggtgtgaaa caagattctg ataatggttt gtgtgagatt tgatcatagt ctaaaactat     1260

cacgtctgag ttgccttagg atgacagtgc tgacacccag taggaagtat cccattttta     1320

tcaggaaagt cagtcacgcg tagggatggt gaggagacgc gtagggatgg tgaggagggg     1380

agaggaggga gacctgctgg tgcccttgca ccagggtgag gcctgactca cgctgcttcc     1440

ccccacaggc cctgctttgc ttgcctgctt tttccagaat cgattttgca agcttcaaga     1500

ttctgttccc ctcttcgcag aagtgaggaa ggcaaatact cagggtttga agggagacct     1560

ggccggcctg agggctggca gatgtgaggg caggacacct gggatggact cgtaggctga     1620

cccaggccca aagggggctg cctgttccca actctttcac tctgtaaccc attttaaaat     1680

gagtttttga atcttgcctc aaattgacct acttggataa aatcagtgct tttcctaact     1740

tgattttgtt tgacgtggtt ccctctaaga gaatggtagg aattgaaact atttgtatat     1800

gttgaaattt gtaggggttc aggaacccat ggcagaaaca ctaaactatt tatttacaag     1860

tatgactatt tttttttcaa agtaggcaat tctttgtata ttttaaggca aataatcact     1920

tcacctctgg tgccttccat gcgtcgcata agcactcttg tcaatcatgg aattggaaaa     1980

aaagatgtac atttagttaa acaagataac actatttttg tagcatgatt ttagattgtg     2040

tccttttaat attgttttca acaatggtag ttttgaggtt ttggccattt tctctttaca     2100

cttcgtatgt attttaaaga agaaaaaaaa caaaaaaaat tccctggcta ttcctctttc     2160

ctctctgctg ctgcttctcc tgcatcttgt tcctgcttat ttaaatagtc tgagagtaag     2220

agtatatttc tgtgaaataa ttataagtca gtataattgc atttggcatt ttttaaccac     2280

ttgctcagtt tggagccact gctcacctca aacagtacaa agaaagtggt tccatatttt     2340

acaaacagaa gagtagcatc agagccctga cctcctgtct ttgggtgtaa aatggtgaga     2400

ggccggtgtc cggctccttc ccctgtggtt tgggctggtg aactgagccc aagtgtattc     2460

tctggcctgg gccccttcca gaatcagtgc gagcgtcctg cagaggcatg gccttcctgc     2520

cactgcagag tgggaagctt cctgggggac ctcagccagc tccggggctc tcatcttcca     2580

ctcggatctc agattggttc gttgtggatg ctctggctag gctcggcggc cttttccagg     2640

cttcaggcct gaacaaaaca ggctgtttgc tgtgaggagc tagatgacac caagacacag     2700

acacgtactc ttcaccggct ccttttgctt ctccttcctg caggacgtga gttatgtctg     2760

gtcccaaaac ccttgagtaa actagctgag ccattgcaaa tgaaggtaca gatggattga     2820

aacataaaat tgtagctttt ggtgtccttc tgaagggtca gaatatgtaa ttatttgata     2880

accaaggaag tcaagtcaga tggctaagta gtaactttcc aatatgattt ctccgtggta     2940

cttcacctgg tggcactttt ggggggcaat gttaacaact atcacatttt actcatcaag     3000

tctctttcat ttcggcagtt taaagacaca actgtgggct ttctgaggcg atgcccgttg     3060

ggcaaactta ggtttatgtg tttggttttt cagctgacgt ggaagccctg ggtgggcgtc     3120

ccctggctgg cctggctttt gggttcaagt ctgtatgtat ggagtgggtt ggggccccaa     3180

agctttgctg ctattgattt gtccccgaca gcaggcaaag cctcacattg ccctcaattt     3240

tccccctttc atttgaagga ccagtttttc atggtacttg tcttgatctt tttcatagtg     3300

ttcaaatctg tatttttgta tgtagaggga aataattttc tcaacactaa tcgttaataa     3360

ctattgtatt aaattgtcat gaaggaactt gtttaataaa tggacgtgta aggaaaaaaa     3420

aaaaaaaaaa                                                            3430


<210>  164
<211>  3584
<212>  DNA
<213>  homo sapiens

<400>  164
gcaagagggc ggaacgcggg acgccaggca ccctagctcc cgacggacgc agttttcagt       60

tgcacgggcg agctccgggc cggctgcgga gcgactcccc gccgccaagt gggcggcgtg      120

gctgtcggga aagaagggct ggggcctgcc gttcttcctc ccgagtatcc cctccagctg      180

gacgacccca cgctgcagca cgggcttccg gcttctctcc tcagtggcca attcgagggc      240

acagcgggct ccggaggcgc ggcggcaagc ctatcccgcc tcccaaccac agcctccagc      300

acccgagaga acggccgccc acagcacacg ttctccggac aggagggcga aggcccaaga      360

cctggagaga tgggcagctc tcaaaaaagg cacaaacaat tgaaggatgg ataccatggc      420

atatgttaaa agcgtgttga aaggaaaata agaaagccag gaatctcagg atgaatcagt      480

ctagatcgag atcagatggt ggcagtgaag aaaccttacc tcaagaccat aatcatcatg      540

aaaatgagag aagatggcag caagagcgtc tccacagaga agaggcctat tatcagttta      600

ttaatgaact caatgatgaa gattatcggc ttatgagaga ccataatctt ttaggcaccc      660

ctggagaaat aacatcagaa gaactgcaac agcggttaga tggcgtcaag gaacaactag      720

catctcagcc tgacttgaga gatggaacga attacagaga ctcagaagtc cctagagaaa      780

gttcacatga agattctctt ctagaatggt tgaacacctt tcggcgcaca ggaaatgcaa      840

ctcgaagtgg acaaaatggg aaccaaactt ggagagctgt gagtcgaaca aacccgaaca      900

atggagagtt tcggtttagt ttggaaatcc acgtaaatca tgaaaataga ggatttgaaa      960

ttcatggaga agattataca gacattccac tttcagatag taacagagat catactgcaa     1020

ataggcaaca aaggtcaact agtcctgtgg ctaggcgaac aagaagccaa acctcagtga     1080

atttcaatgg tagtagttcc aacattccaa ggactaggct tgcttcaagg gggcaaaatc     1140

cagctgaagg atctttctca acattgggaa ggttaagaaa tggaattggg ggagcagctg     1200

gcattcctcg agctaacgct tcacgcacta atttcagtag tcacacaaac caatcaggtg     1260

gtagtgaact caggcaaagg gaggggcaac ggtttggagc agcacatgtt tgggaaaatg     1320

gggctagaag taatgttaca gtgaggaata caaaccaaag attagagcca ataagattac     1380

gatctacttc caatagtcga agccgttcac caattcagag acagagtggc actgtttatc     1440

ataattccca aagggaaagt agaccagtac agcaaaccac tagaagatct gttaggagga     1500

gaggtagaac tcgagtcttt ttagagcaag atagagaacg agaacgcaga ggtactgcat     1560

ataccccatt ctctaattca aggcttgtgt caagaataac agtagaagaa ggagaagaat     1620

ccagcagatc ctcaactgct gtacgacgac atccaacaat cacactggac cttcaagtga     1680

gaaggatccg tcctggagaa aatagagatc gggatagtat tgcaaataga actcgatcca     1740

gagtagggct agcagaaaat acagtcacta ttgaaagcaa tagtgggggc tttcgccgaa     1800

ccatttctcg tttagagcgg tcaggtattc gaacctatgt tagtaccata acagttcctc     1860

ttcgtaggat ttctgagaat gagcttgttg agccatcatc agtggctctt cggtcaattt     1920

taaggcagat catgactggg tttggagaac tgagttctct aatggaggcc gattctgagt     1980

cagaacttca aagaaatggc cagcatttac cagacatgca ctcagaactg agtaacttag     2040

gtacagataa caacaggagc cagcacaggg aaggttcctc tcaagacagg caggcccaag     2100

gagacagcac tgaaatgcat ggtgaaaacg agaccaccca gcctcatact cgaaacagtg     2160

acagtagggg tggcaggcag ttgcgaaatc caaacaattt agttgaaact ggaacactac     2220

ccattcttcg ccttgctcac ttttttttac taaatgaaag tgatgatgat gatcgaatac     2280

gtggtttaac caaagagcag attgacaatc tttccaccag gcactatgag cataacagta     2340

ttgatagtga actaggtaaa atctgtagtg tttgtattag tgactatgta actggaaaca     2400

agctcaggca attaccttgc atgcatgaat ttcacattca ttgtattgac cgatggctct     2460

cagagaattg cacttgtccg atctgtcggc agcctgtttt agggtctaac atagcaaaca     2520

atgggtaagg tgatgggatc tactcaaata ctgtttttta gtagaactga atgttcaagc     2580

attgttttgc tgagttattt gtgattagct aaccaggatg aaaaataaca gattatatat     2640

agtttgaact atttttcgtg tgctttttta aacttgttaa aaagaaattt atataaaatt     2700

taaaatacaa atgttaaatt atccagaaat acagaatagt taatattgct agaaccaaat     2760

aacctctaaa atgtttttat tttggtaatt ttgtcatgct aagcactttt gtatctgcac     2820

aattcagtag gttaagaatc aatcttcttt ttcttaatag tacagcagac tttagcttca     2880

agtttcatag gcttagtact tatatctaga catttgtgtc taaataagct tttcattaac     2940

tttttatttt aaggacagta tcttttcatg aaagagtatt tggctgaatg tttgctatat     3000

atatgttact tgaaatgtta aatttaatat gcagcatacc ataggtgtat atataggtat     3060

ataattttaa ggttaaaata ttcagtctac aagtttggtt cttatttaag cttttgggct     3120

aatactgcat atggcacaat gtttaatatt ggcaagttca tctcagagaa aggggattca     3180

gatataattt taaagtagag ataatttact gaagcgtctc tgacaatcta acttattaga     3240

cagcaagcaa tatataatac tgaaaaagta ttcagaaatg gaaaatttac atcatatagg     3300

ttatttaact tgtgttcagc ctttttgtaa cttttttgaa agtgcaaaca attctttgga     3360

ttattaaata aggtatacag tatgcatggt ttctcaaatt tagttttaaa atctaaaagt     3420

ctataaagaa tcagatgcat aggcaatatg ttaagttcac ttggaggcta aaaatctcca     3480

gtgaaaacaa aacgaaaacc tttaagagaa tgtagagttt atataaacac aaagtatgca     3540

ttgaagatct gtttctacca ataaacatta aaacaaagac tgta                      3584


<210>  165
<211>  3339
<212>  DNA
<213>  homo sapiens

<400>  165
attgcgctcc gctggctggt gattggttgg gatgcaccgt ctatcacctg cttccttgtg       60

agaatctagg tctctaaggg aagcgttact tgaggctcgg ttgggaagag atgggcagct      120

ctcaaaaaag gcacaaacaa ttgaaggatg gataccatgg catatgttaa aagcgtgttg      180

aaaggaaaat aagaaagcca ggaatctcag gatgaatcag tctagatcga gatcagatgg      240

tggcagtgaa gaaaccttac ctcaagacca taatcatcat gaaaatgaga gaagatggca      300

gcaagagcgt ctccacagag aagaggccta ttatcagttt attaatgaac tcaatgatga      360

agattatcgg cttatgagag accataatct tttaggcacc cctggagaaa taacatcaga      420

agaactgcaa cagcggttag atggcgtcaa ggaacaacta gcatctcagc ctgacttgag      480

agatggaacg aattacagag actcagaagt ccctagagaa agttcacatg aagattctct      540

tctagaatgg ttgaacacct ttcggcgcac aggaaatgca actcgaagtg gacaaaatgg      600

gaaccaaact tggagagctg tgagtcgaac aaacccgaac aatggagagt ttcggtttag      660

tttggaaatc cacgtaaatc atgaaaatag aggatttgaa attcatggag aagattatac      720

agacattcca ctttcagata gtaacagaga tcatactgca aataggcaac aaaggtcaac      780

tagtcctgtg gctaggcgaa caagaagcca aacctcagtg aatttcaatg gtagtagttc      840

caacattcca aggactaggc ttgcttcaag ggggcaaaat ccagctgaag gatctttctc      900

aacattggga aggttaagaa atggaattgg gggagcagct ggcattcctc gagctaacgc      960

ttcacgcact aatttcagta gtcacacaaa ccaatcaggt ggtagtgaac tcaggcaaag     1020

ggaggggcaa cggtttggag cagcacatgt ttgggaaaat ggggctagaa gtaatgttac     1080

agtgaggaat acaaaccaaa gattagagcc aataagatta cgatctactt ccaatagtcg     1140

aagccgttca ccaattcaga gacagagtgg cactgtttat cataattccc aaagggaaag     1200

tagaccagta cagcaaacca ctagaagatc tgttaggagg agaggtagaa ctcgagtctt     1260

tttagagcaa gatagagaac gagaacgcag aggtactgca tataccccat tctctaattc     1320

aaggcttgtg tcaagaataa cagtagaaga aggagaagaa tccagcagat cctcaactgc     1380

tgtacgacga catccaacaa tcacactgga ccttcaagtg agaaggatcc gtcctggaga     1440

aaatagagat cgggatagta ttgcaaatag aactcgatcc agagtagggc tagcagaaaa     1500

tacagtcact attgaaagca atagtggggg ctttcgccga accatttctc gtttagagcg     1560

gtcaggtatt cgaacctatg ttagtaccat aacagttcct cttcgtagga tttctgagaa     1620

tgagcttgtt gagccatcat cagtggctct tcggtcaatt ttaaggcaga tcatgactgg     1680

gtttggagaa ctgagttctc taatggaggc cgattctgag tcagaacttc aaagaaatgg     1740

ccagcattta ccagacatgc actcagaact gagtaactta ggtacagata acaacaggag     1800

ccagcacagg gaaggttcct ctcaagacag gcaggcccaa ggagacagca ctgaaatgca     1860

tggtgaaaac gagaccaccc agcctcatac tcgaaacagt gacagtaggg gtggcaggca     1920

gttgcgaaat ccaaacaatt tagttgaaac tggaacacta cccattcttc gccttgctca     1980

ctttttttta ctaaatgaaa gtgatgatga tgatcgaata cgtggtttaa ccaaagagca     2040

gattgacaat ctttccacca ggcactatga gcataacagt attgatagtg aactaggtaa     2100

aatctgtagt gtttgtatta gtgactatgt aactggaaac aagctcaggc aattaccttg     2160

catgcatgaa tttcacattc attgtattga ccgatggctc tcagagaatt gcacttgtcc     2220

gatctgtcgg cagcctgttt tagggtctaa catagcaaac aatgggtaag gtgatgggat     2280

ctactcaaat actgtttttt agtagaactg aatgttcaag cattgttttg ctgagttatt     2340

tgtgattagc taaccaggat gaaaaataac agattatata tagtttgaac tatttttcgt     2400

gtgctttttt aaacttgtta aaaagaaatt tatataaaat ttaaaataca aatgttaaat     2460

tatccagaaa tacagaatag ttaatattgc tagaaccaaa taacctctaa aatgttttta     2520

ttttggtaat tttgtcatgc taagcacttt tgtatctgca caattcagta ggttaagaat     2580

caatcttctt tttcttaata gtacagcaga ctttagcttc aagtttcata ggcttagtac     2640

ttatatctag acatttgtgt ctaaataagc ttttcattaa ctttttattt taaggacagt     2700

atcttttcat gaaagagtat ttggctgaat gtttgctata tatatgttac ttgaaatgtt     2760

aaatttaata tgcagcatac cataggtgta tatataggta tataatttta aggttaaaat     2820

attcagtcta caagtttggt tcttatttaa gcttttgggc taatactgca tatggcacaa     2880

tgtttaatat tggcaagttc atctcagaga aaggggattc agatataatt ttaaagtaga     2940

gataatttac tgaagcgtct ctgacaatct aacttattag acagcaagca atatataata     3000

ctgaaaaagt attcagaaat ggaaaattta catcatatag gttatttaac ttgtgttcag     3060

cctttttgta acttttttga aagtgcaaac aattctttgg attattaaat aaggtataca     3120

gtatgcatgg tttctcaaat ttagttttaa aatctaaaag tctataaaga atcagatgca     3180

taggcaatat gttaagttca cttggaggct aaaaatctcc agtgaaaaca aaacgaaaac     3240

ctttaagaga atgtagagtt tatataaaca caaagtatgc attgaagatc tgtttctacc     3300

aataaacatt aaaacaaaga ctgtaaaaaa aaaaaaaaa                            3339


<210>  166
<211>  2272
<212>  DNA
<213>  homo sapiens

<400>  166
gcgggcggct gtgagcggcg ctcggggcgc gctaggcggg gagccgagcc gggctggcgg       60

caggcggacg gggcgggcgc gtgcggcgcg agccgggcgc tgaggacaag ggccgctggt      120

agggccggcc ggccggcggg cggagcgccg ccgccgacgc acacgaggtg accaggcatt      180

gatgcacccc caggaaggcc acgcgctcag gaggcccccc cgccccgctg gctgctgctc      240

acatggtgtc tgggcccttg gcactctgtt catgcgggag atggcagggg ctggcacatg      300

acagtggagc agaaatttgg cctgttttct gctgagataa aggaagcaga ccccctggct      360

gcctcggaag caagtcaacc caaaccctgt ccccccgaag tgacccccca ctacatctgg      420

atcgacttcc tggtgcagcg gtttgagatc gccaagtact gcagctctga ccaagtggag      480

atcttctcca gcctgctgca gcgctccatg tccctgaaca tcggcagggc caaggggagc      540

atgaaccggc acgtggcggc catcgggccc cgcttcaagc tgctgaccct ggggctgtcc      600

ctcctgcatg ccgatgtggt tccaaatgca accatccgca atgtgcttcg cgagaagatc      660

tactccactg cctttgacta cttcagctgt cccccaaagt ttcctactca aggagagaag      720

cggctgcgtg aagacataag catcatgatt aaattttgga ccgccatgtt ctcagataag      780

aagtacctga ccgccagcca gcttgttccc ccagctgaca tcggcgacct cctggagcag      840

ttagtagagg agaacacagg ctccttgtcg ggcccagcga aggactttta ccagcgggag      900

tttgatttct ttaacaagat caccaacgtg tcggctgtca tcaagcccta ccctaaaggc      960

gacgagagaa agaaggcttg tctgtcggcc ctgtctgaag tgacggtgca gccaggctgc     1020

tccctgccca gcaaccccga agccattgtg ctggacgtcg actacaagtc tgggaccccg     1080

atgcagagtg ctgcaaaagc cccatatctg gccaagttca aggtgaagcg atgtggagtt     1140

agtgaacttg aaaaagaagg tctgcggtgc cgctcagact ctgaggatga gtgcagcacg     1200

caggaggccg acggccagaa gatctcctgg caggcagcca tcttcaaact gggagacgac     1260

tgccggcagg acatgctggc cctgcagatc atcgacctct tcaagaacat cttccagctg     1320

gtcggcctgg acctctttgt ttttccctac cgcgtggtgg ccactgcccc tgggtgcggg     1380

gtgatcgagt gcatccccga ctgcacctcc cgggaccagc tgggccgcca gacagacttc     1440

ggcatgtacg actacttcac acgccagtac ggggatgagt ccactctggc cttccagcag     1500

gcccgctaca acttcatccg aagcatggcc gcctacagcc tcctgctgtt cctgctgcag     1560

atcaaggaca gacacaacgg caacattatg ctggacaaga agggccatat catccacatc     1620

gactttggct tcatgtttga aagctcgccg ggcggcaatc tcggctggga acccgacatc     1680

aagctgacgg atgagatggt gatgatcatg gggggcaaga tggaggccac acccttcaag     1740

tggttcatgg agatgtgtgt ccaggctacc tggctgtgcg gcacaggttt agccccaaca     1800

tgactgagcg cgaggctgca aatttcatca tgaaggtcat ccagagctgc ttcctcagca     1860

acaggagccg gacctacaac atgatccagt actatcagaa tgacatcccc tactgaggag     1920

gggaccttcg agggcctctg ccccatgtgc ccttgaagct gccccacaat catggagccc     1980

tgcgacctac ccgccctgcc gccacatgca gtggaggaga ggcctgtggc ccgaagagcc     2040

tggtagcgcc tcctggggca gcacgtgggt ggcgcaggct tagtaacgcc gtggactgca     2100

gcgacaatca gtggatggtg ctgtctatgc acaggtgtga gtcctctgtt tgcactggac     2160

atattcccta cctgttttat ttcataggta catgaagtat tgtgtataaa aaaagagata     2220

agatttaacc aacatcaaca aaataaaaac ccaaaatagt gctgtgttgg aa             2272


<210>  167
<211>  4256
<212>  DNA
<213>  homo sapiens

<400>  167
gccgcggcgg tggggttggc agggtgtgct ggggcctgga ggaggcgccg cgcggccagg       60

gagccagcgg gaggccgcgc ctggcaggtt tctgaaacag atcgtgagct tcatcaagag      120

aattcaactg gaaaaccaag actggtagac tctctttttc ttcagacaat aggcaggagc      180

caggcagagt ccagggattc ttggaacacc tatcttttct tcggaggaca ctaagttcta      240

tttgaagaca aagttcaata tggcaacagg actgatggga cacgaaggag tcgctaccgt      300

gatttggtga cagttcttca aaacgacagt gtctcaagga aaggtggacc taggaactcc      360

tgaacttttg ggttgcctta agtgagaaat cagcatggct caggcaagtc tcctggcttg      420

tgaaggccta gcaggtgtga gtttggttcc cactgcagcc agcaagaaga tgatgctgag      480

ccagattgcc agcaagcagg ccgagaatgg cgagcgggca ggtagccctg atgtgctgag      540

gtgctcgagt cagggtcacc gaaaagacag tgataagtcc cggagccgca aagatgatga      600

cagcttgtct gaggcctctc attcaaaaaa gactgttaaa aaggtggtgg tagtggaaca      660

aaatggttct tttcaagtaa agattcccaa aaattttgtt tgtgaacact gctttggagc      720

ctttcggagc agttaccacc taaagaggca catccttatt cacactggtg agaagccatt      780

tgaatgcgat atatgtgata tgcgtttcat ccagaagtac cacctggaac gccacaagcg      840

tgtgcacagt ggtgaaaagc cttaccagtg tgaacggtgt catcagtgtt tttctcggac      900

agatcgatta ctcagacaca aacggatgtg ccaagggtgc cagtccaaga cttccgacgg      960

gcagttttct ctataggcgc aaggggcccc gggtggtggg agtgatcaga agaacctgcc     1020

gaagagcaca ccccctctgg tctgatggtc ccaccaccgc cccatgtgaa cctgtcccac     1080

tcctggagga gtggacccag gagaccagaa gagtgcatca ggggacagtg gccccagaac     1140

ctcagctctg taaataatct gagactatga gtatctcggg gaagttctta cagcattcct     1200

gggtagggga gctagtccct ggacccttgg ctgaggtcat aggtggggac tcaaggtaca     1260

ggaccaagac tgaagtgtgg ctcccacaac cttggactcc agctggcagc tgaaatggaa     1320

aagattgggg aaggggattt gtttgttctg ttcttgtttt tgtttatcca aaagcaactt     1380

cagcgggtaa actgtggata caggtaatcc agaggcataa gagtcctggt ccaaagtagg     1440

gactatagct ggtccagctc tccccaaaaa ttgggttttt agttgcagta gctcctcagt     1500

gtttcacaat cctgcacttc gcctcctttt tgaggaagaa taaggtcagg aatggcagct     1560

gagcttactt tggcttcctt atacactgta gggacaaaag gaaaaacggg gtggagcaga     1620

caagggctgg atccaaaaag tggatggcac ctcttccttc ctcaagggaa aaggaagagt     1680

tgtgccagtg ggtgttgtca tggcccatgt cacattggca cctgatggca tcagctcaaa     1740

tgcctttagg aggaaacttg ggtgagagtg gcccatgaag cccttttctt ctttttttgg     1800

ggagtcggtc ttggagatgg tatgtggcta cctcgctgcc attgactcct aaagtgagac     1860

agatgtgttg agcaaggagt catggaagtc aaagtgggtt ctctctcctt gtgccctctt     1920

aggaacaacc caagactggt cccaagttgg ctaacagctg ctcaagaaac aaaggaatct     1980

ggggtcttct gacatgcctg ttgagcagta ggagctgttc tccctcccca agtcctatca     2040

ctgtattcag gtagaggagg tagggagggg tctgtccttt ggtcccaaaa aacaagatct     2100

cggcttgctt cctgatggcc atccctaccc aacagagtgt gggggatggg ggtgggggtg     2160

ctgcagagaa aagactaaag aagaaaccta atgtaggttc cattcttaac catattcttt     2220

gctcctctct gctccaatac caccaccttg tccactccca aaaaagtaat cgggtgtgtg     2280

tgtgtgtgtg agagagagtg tgtgtgagat atgaatgcat gtatttgtat gcttgcagga     2340

gatggcatat tattgagcca aacccttctc tggccctcac cttcagggag gatgagtgga     2400

aaatagcctc ctcttgccca aacatgaagg gtgcttgagg tctcagcagg agctgaagaa     2460

cacaatttgg ggaacagaag ggcttttgtt ttggagggtt ttttttttta agatgaattc     2520

aacagcctgg tggttaggat gtttctaacc caagccaggg cttgtgaaca tgaattttct     2580

aaggtgaaat aaaccttttc tttctgctaa agaaagaatc cttatgggaa gttttggggt     2640

ttggttgacc cccactgtaa cctgacctga cctgtggcgg gtacgggaac tgtcttagta     2700

atcatggaga ctggctgaac ctgagtgcca agctgtcagt agggtctgag atgggaaact     2760

cctgaaagta tgatttcatt tcccagaaaa tgtaaagaat ggataccagc aatgattcct     2820

ggctgttacc tattctggag gggtggggtt ggggaggggg ttgtccatac ctctgtggta     2880

tgagtatttc agggaaaaag aaagcaggca tggcacccat tcgattttcc ctgacagcat     2940

ctgagatcct tttggggaga cgctgaggag tgtttgctgc catgtactct tacagctcta     3000

tgctgacact cccatttgat gtggtccaga acttagacct cagtccttgg atcagccctg     3060

tggtccctgc aagcaggggc atctttctgc atgtgagcca gcccccttcc tgttcaaggg     3120

ttctgctgga tctgggcttt tcctgtcctt cacttctggg atgattcacc ccacatcttc     3180

cagtaccctg taaaccattt taaaatattt agaaaactat cctcccaaaa atgcttttga     3240

aaatgagagc cctctgtccc tgccacttac agctagtctc tttgggatag gggtgtatgt     3300

ggagagattc atgtaagtct cacatgagtg acctgtgccc ctatgtgtac taatgtgtgt     3360

actgggtcag aaggtgccct gggttcccac agaccttggt ttcctgcctg ggtgggtggg     3420

agggagggaa cttcagagag tatgtgcgaa cagccatagc agagccaccc ctgccaagga     3480

cccagtgagg gaaactcagg agcaggtggt tggttcagtt cccgcgctga tgtctggggc     3540

agtgcatgtg tgagaagaga ggcgcaaagc agtgaaagga gtgatttggc atccagaggg     3600

cccgggagcc ccacggatac cccagggaag ccactgactc acaccgctgc agaggctcct     3660

gggcccaatg cccgacccct gctggccagc atggggccta gcactggaag atgcctcagg     3720

tgtgtttgga gtgggggaaa cggaagtagg gcacgctctc agagaccagg atagagagtc     3780

agggaacctg ggaaagagta gtgccagttc cgggtaggct gctgcaccag gccctaccag     3840

ctcaggctat aaacagtctg ctttgcccca agtcttttcc gtccaccccc aacagccttg     3900

tcatcactta gctactgatc acgcccatgg cttgacattg gagggttaca ttagtggagt     3960

ccgccacagc ttcgaaccct ctccccagat gccctttgcc tctgctgtgg ccctggggtt     4020

ttatcaactg tccccttcct atcctcctct ccaccctgtt ttttgttttt ttttttttta     4080

aataatattt tgctatgggg gaggggaata tcaaatggac aagatcactt ttaaatggta     4140

gtttttataa gatgttataa acttgtatct ttttaccatt aaagtgcagt gtatgttcct     4200

tcgtgatata tttaggatat ttaaataaaa ggaaaatggg gcttttctac atacta         4256


<210>  168
<211>  3616
<212>  DNA
<213>  homo sapiens

<400>  168
ctctgctctc ctcccagtct cccccgcgct gcgtgcagta aggtagccgc cgccgccgcc       60

gccgccgcgt cccctcgccg gctcgctggt accggcagtg ccatggcggc cttcagcaag      120

tacttgacgg cgcgaaactc ctcgctggct ggtgccgcgt tcctgctgct ctgcctgctc      180

cacaagcggc gccgcgccct cggcctgcac ggtaagaaaa gtggaaaacc accattacag      240

aacaatgaga aagaggggaa aaaggagcga gctgtggtgg acaaggtgtt tttctcaagg      300

ctcatacaga ttctgaaaat catggtccct agaacatttt gtaaagagac aggttacttg      360

gtacttattg ctgttatgct ggtgtctcga acatattgtg atgtttggat gattcaaaat      420

gggacactaa ttgaaagtgg tatcattggt cgtagcagga aagatttcaa gagatactta      480

ctcaacttca tcgctgccat gcctcttatc tctctggtta ataacttctt gaagtatggg      540

ttaaatgagc ttaaactgtg cttccgagta aggctcacta aatacctcta tgaggagtat      600

cttcaagctt tcacatatta taaaatgggg aatctggaca acagaatagc taatccagac      660

cagctgctta cacaagatgt agaaaaattt tgtaacagtg tagtcgatct gtattcaaat      720

cttagtaagc catttttaga catagttttg tatatcttta agttaacgag tgcaattgga      780

gctcagggcc cagcgagcat gatggcctac ttggttgttt ctgggctatt cctaactcga      840

cttcgaagac ccattggtaa gatgacaata actgagcaaa agtatgaagg agaatataga      900

tatgttaatt ctcggctcat cacaaacagt gaagaaattg ccttttacaa tgggaataaa      960

agagaaaagc agacagtcca ctcagtcttc cgaaaactgg tggaacacct acataatttc     1020

attttgtttc ggttttcaat gggcttcatt gatagtatta ttgccaaata ccttgccact     1080

gttgttggtt acctagttgt cagtcgccct ttcttagatt tgtctcatcc tcgacatctc     1140

aagagtacac attcggaact tctagaggat tactaccaaa gtggaagaat gcttttgcga     1200

atgtctcaag ctctgggtcg aatagttttg gctgggcgtg aaatgactag attggccggt     1260

tttactgctc ggattacaga attaatgcaa gtactgaagg atttaaatca tggcaaatat     1320

gagcgcacaa tggtctcaca acaggaaaag ggtattgaag gagtacaagt cattcccttg     1380

atacctggtg ctggagaaat cattattgca gataacatta taaagtttga tcatgttcct     1440

ttagcaacgc caaatggaga tgttttgatc cgagacctta attttgaagt tcgatctggg     1500

gctaatgttc taatttgtgg tccaaatggc tgcggaaaga gttcactttt ccgtgttctt     1560

ggtgaattat ggcctctttt tggaggacgt ctaactaaac ctgaaagagg aaaattattt     1620

tatgttcctc agagacctta catgaccctt ggaacacttc gagatcaagt gatatatcca     1680

gatggacgag aagatcagaa aaggaaggga atttctgacc tagtactgaa ggaatactta     1740

gacaatgtcc agttgggtca tatccttgaa cgtgaaggag gctgggacag tgttcaggat     1800

tggatggacg tactcagtgg tggagaaaag caaagaatgg cgatggcaag attattttat     1860

cataaacccc agtttgccat tttggatgaa tgcacaagtg cagttagtgt cgacgtggaa     1920

ggctacattt atagtcattg tcgaaaggtt ggcatcactc tcttcactgt gtctcatagg     1980

aaatctcttt ggaaacatca tgagtactac ctgcatatgg atggcagagg caactatgaa     2040

ttcaaacaga taacagaaga tacagttgag tttggctctt agagaaatct ggagaactat     2100

acctgcttca gtgaaataat tacagaatat acttagaaag gcaaagtaca ttgtaaaata     2160

aagttgagct tagttttttt taaaaaaaaa aacaaagcaa caaattaact agatacagaa     2220

taatggagaa caagttgtta aaacatttaa tattatatag gatattgcta attgtgtata     2280

tgttggttta attaataata tgtactaaga atgtccttat tcttgtggtt aaaaacctgc     2340

ctaaattaaa ttgggcttca atcactgtaa cctgattcat cctgggatgt aaaccattcg     2400

aagtcagcta attggacttt tatggctcta tcttttcctt cagtgaagaa ccctatttaa     2460

aactgggtca tcatttgtcc tgttctagca agatagtctt cagtttcatt ttcctgtgcc     2520

ctgtggtagt tggaaacaaa tcataatgta ttatttaaat gtttaacatc attgcataac     2580

agcgtttatt atacagtggc agatttcttt agctgccaca gtaatactca ttccttgtgt     2640

gtgtcttgga gtgcatttga ctccaggaaa agccattttg gttttcctta actaaatgat     2700

aaatgtaccc ctctcagtct gcagtattga gttgtttaaa gtatatgtgc agtcttgctt     2760

acaaggaggg gttaccatgt atcacaccta atcttcccaa tgtttgggat attaaaacac     2820

aaagtcctta acatgccagg ctcaaggtct tataagagtt ctagattttt aagagaatta     2880

gacaaatttg tgtgtgttag aagcccattc attagaagtg tggtggttat ttggtattaa     2940

actccaaatg agccatagga aggcactaca tgaaataatg cactgagtat gcaatgctat     3000

cactgtcttt gactgtgatt ttatgtttaa aaagtatgtt ctaaaattat tatatataca     3060

tgggtgaatt atgtttccga ggcactgttt tatctctgtg aatcttgaat aactttttta     3120

tatttgggtt atgatgtcaa acgatcctaa gcgaagatga tttcagttca tcaaatcatc     3180

attaatgact ttatgtatta tttgcacagg gagaattgaa actgagtata atcaataagc     3240

tagatacgaa atcagtttct caaactgagc ttcagaaagg ggcattttgt actcttgttt     3300

ttgcataact ggttttgttt ttttgcagaa ttaactataa caatcactgg ctaccgaagt     3360

aaactgatgt actgaattcc ataatacata acattcaatt tttaccactt ctgtttagcg     3420

aacttgtata cttattttct gttcagatta aaaaaaaaaa aaaaaaactc agatatccta     3480

tacaaccttt gcttgttctt tttattctgg tatctaaata ctgagaagtt catttataat     3540

tcagccttga cttgaaaaca tagatagttt aatcttgact tgaaaaacac aaaaataaat     3600

tcagaaaatg ctttta                                                     3616


<210>  169
<211>  2965
<212>  DNA
<213>  homo sapiens

<400>  169
aaagcaggcc tgtcccttta agggggttgg ctgtcaatca gaaagccctt ttcattgcag       60

gagaagagga caaagatact cagagagaaa aagtaaaaga ccgaagaagg aggctggaga      120

gaccaggatc cttccagctg aacaaagtca gccacaaagc agactagcca gccggctaca      180

attggagtca gagtcccaaa gacatgggct tgttagagtg ctgtgcaaga tgtctggtag      240

gggccccctt tgcttccctg gtggccactg gattgtgttt ctttggggtg gcactgttct      300

gtggctgtgg acatgaagcc ctcactggca cagaaaagct aattgagacc tatttctcca      360

aaaactacca agactatgag tatctcatca atgtgatcca tgccttccag tatgtcatct      420

atggaactgc ctctttcttc ttcctttatg gggccctcct gctggctgag ggcttctaca      480

ccaccggcgc agtcaggcag atctttggcg actacaagac caccatctgc ggcaagggcc      540

tgagcgcaac gtttgtgggc atcacctatg ccctgaccgt tgtgtggctc ctggtgtttg      600

cctgctctgc tgtgcctgtg tacatttact tcaacacctg gaccacctgc cagtctattg      660

ccttccccag caagacctct gccagtatag gcagtctctg tgctgatgcc agaatgtatg      720

gtgttctccc atggaatgct ttccctggca aggtttgtgg ctccaacctt ctgtccatct      780

gcaaaacagc tgagttccaa atgaccttcc acctgtttat tgctgcattt gtgggggctg      840

cagctacact ggtttccctg ctcaccttca tgattgctgc cacttacaac tttgccgtcc      900

ttaaactcat gggccgaggc accaagttct gatcccccgt agaaatcccc ctttctctaa      960

tagcgaggct ctaaccacac agcctacaat gctgcgtctc ccatcttaac tctttgcctt     1020

tgccaccaac tggccctctt cttacttgat gagtgtaaca agaaaggaga gtcttgcagt     1080

gattaaggtc tctctttgga ctctcccctc ttatgtacct cttttagtca ttttgcttca     1140

tagctggttc ctgctagaaa tgggaaatgc ctaagaagat gacttcccaa ctgcaagtca     1200

caaaggaatg gaggctctaa ttgaattttc aagcatctcc tgaggatcag aaagtaattt     1260

cttctcaaag ggtacttcca ctgatggaaa caaagtggaa ggaaagatgc tcaggtacag     1320

agaaggaatg tctttggtcc tcttgccatc tataggggcc aaatatattc tctttggtgt     1380

acaaaatgga attcattctg gtctctctat taccactgaa gatagaagaa aaaagaatgt     1440

cagaaaaaca ataagagcgt ttgcccaaat ctgcctattg cagctgggag aagggggtca     1500

aagcaaggat ctttcaccca cagaaagaga gcactgaccc cgatggcgat ggactactga     1560

agccctaact cagccaacct tacttacagc ataagggagc gtagaatctg tgtagacgaa     1620

gggggcatct ggccttacac ctcgttaggg aagagaaaca gggtgttgtc agcatcttct     1680

cactcccttc tccttgataa cagctaccat gacaaccctg tggtttccaa ggagctgaga     1740

atagaaggaa actagcttac atgagaacag actggcctga ggagcagcag ttgctggtgg     1800

ctaatggtgt aacctgagat ggccctctgg tagacacagg atagataact ctttggatag     1860

catgtctttt tttctgttaa ttagttgtgt actctggcct ctgtcatatc ttcacaatgg     1920

tgctcatttc atggggtatt atccattcag tcatcgtagg tgatttgaag gtcttgattt     1980

gttttagaat gatgcacatt tcatgtattc cagtttgttt attacttatt tggggttgca     2040

tcagaaatgt ctggagaata attctttgat tatgactgtt ttttaaacta ggaaaattgg     2100

acattaagca tcacaaatga tattaaaaat tggctagttg aatctattgg gattttctac     2160

aagtattctg cctttgcaga aacagatttg gtgaatttga atctcaattt gagtaatctg     2220

atcgttcttt ctagctaatg gaaaatgatt ttacttagca atgttatctt ggtgtgttaa     2280

gagttaggtt taacataaag gttattttct cctgatatag atcacataac agaatgcacc     2340

agtcatcagc tattcagttg gtaagcttcc aggaaaaagg acaggcagaa agagtttgag     2400

acctgaatag ctcccagatt tcagtctttt cctgtttttg ttaactttgg gttaaaaaaa     2460

aaaaaagtct gattggtttt aattgaagga aagatttgta ctacagttct tttgttgtaa     2520

agagttgtgt tgttcttttc ccccaaagtg gtttcagcaa tatttaagga gatgtaagag     2580

ctttacaaaa agacacttga tacttgtttt caaaccagta tacaagataa gcttccaggc     2640

tgcatagaag gaggagaggg aaaatgtttt gtaagaaacc aatcaagata aaggacagtg     2700

aagtaatccg taccttgtgt tttgttttga tttaataaca taacaaataa ccaacccttc     2760

cctgaaaacc tcacatgcat acatacacat atatacacac acaaagagag ttaatcaact     2820

gaaagtgttt ccttcatttc tgatatagaa ttgcaatttt aacacacata aaggataaac     2880

ttttagaaac ttatcttaca aagtgtattt tataaaatta aagaaaataa aattaagaat     2940

gttctcaatc aaaaaaaaaa aaaaa                                           2965


<210>  170
<211>  3995
<212>  DNA
<213>  homo sapiens

<400>  170
ccctcggtgc gcgggcacag cagccaggct gccggagagc tgatctcggg gattcgggtg       60

cggagccctt ggcctggagg cgatatgggt ggtccgtggc ccggttcagt cgcttgcagc      120

agcccgggga acaggcctgt ctggccctga gggagtcccc tttctgaagc tgtggtgctt      180

ggacgacctg ctctctacat tgctgggcac ctgtaggtgt ccctcgagag ctcagttttg      240

aggttcaagt cagtgtggcc atgaaggggc tgcctattgg gctgatgctg tgaccctgga      300

gtctgcctct cctgccagtc cccctgcccg gaacatgtgg ctgcggcttg gcccgccctc      360

gctgtccctg agccccaagc ccacggttgg caggagcctg tgcctcaccc tgtggttcct      420

cagtttggcg ctgagggcca gtacccaggc cccagcaccc acagtcaaca ctcactttgg      480

gaagctaagg ggtgcccgag taccactgcc cagtgagatc ctggggcctg tggaccaata      540

cctgggggtg ccctacgcag ctcccccgat cggcgagaaa cgtttcctgc cccctgaacc      600

acccccatcc tggtcgggca tccggaacgc cacacacttt cccccagtgt gcccccagaa      660

catccacaca gctgtgcccg aagtcatgct gccggtctgg ttcactgcca acttggatat      720

cgtcgctact tacatccagg agcccaacga agactgtctc tacctgaacg tctatgtgcc      780

gacggaggat gtaaagcgga tttccaagga atgcgcccga aagcccaaca agaaaatttg      840

taggaaagga ggatccggcg ctaagaaaca gggcgaggac ttagcggata atgacgggga      900

tgaagatgaa gacatccggg acagtggtgc taaacccgtc atggtctaca tccacggagg      960

ctcttacatg gaagggacag gcaacatgat tgatggcagc atcctcgcca gttatggcaa     1020

tgtcatcgtc atcaccctca actatcgggt tggagtgcta ggtttcctga gtactggaga     1080

tcaggctgcc aagggcaact atgggctcct tgaccagatc caggccctcc gctgggtgag     1140

cgagaatatt gccttcttcg ggggagaccc ccgccggatc actgtctttg gctcgggcat     1200

tggtgcatcc tgcgtcagcc tcctcacgtt gtcacatcac tcagagggac ttttccagag     1260

agccatcatc caaagtggct ctgctctgtc cagctgggct gtgaactacc aaccagtgaa     1320

gtacaccagc ctgctggcag acaaagtggg ctgtaatgtg ctggacaccg tggatatggt     1380

ggactgtctt cggcaaaaga gtgccaagga gctggtagag caggacatcc agccagcccg     1440

ctaccacgtg gcctttggcc ctgtgattga tggtgatgtc attcctgatg accctgagat     1500

cctcatggag cagggcgagt tcctcaacta tgacatcatg ctaggtgtca accagggcga     1560

gggtctcaag tttgtggaag gggtggtgga ccctgaggat ggtgtctctg gcactgactt     1620

tgactattcc gtctccaatt ttgtggacaa tctgtatggc tatcctgagg gtaaggacac     1680

cctgcgagag accatcaagt tcatgtatac agactgggca gaccgtgaca accctgagac     1740

ccgccgtaaa acactggtgg cactcttcac tgaccaccag tgggtggagc cctcagtggt     1800

gacagccgat ctgcatgccc gctacggctc gcctacctac ttctacgcct tctatcatca     1860

ctgccagagc ctcatgaagc ctgcttggtc agatgcagct catggggatg aagtacccta     1920

tgtttttggg gttcctatgg taggccccac tgaccttttc ccctgcaact tctccaagaa     1980

tgatgttatg ctcagtgctg tcgtcatgac ctattggacc aactttgcca agactgggga     2040

tcccaacaag ccggtccccc aggacaccaa gttcattcac accaaggcca accgctttga     2100

ggaagtggcc tggtccaaat acaatccccg agaccagctc taccttcaca tcgggctgaa     2160

accaagggtc cgagatcatt accgggccac taaggtggcc ttttggaaac atctggtgcc     2220

ccacctatac aacctgcatg acatgttcca ctatacgtcc accaccacca aagtgccgcc     2280

tccggatacc acccacagct cccacatcac ccgcaggccc aatggcaaga cctggagcac     2340

caagcggcca gccatctcac ctgcctacag caacgagaat gcccaggggt cctggaacgg     2400

ggaccaggat gcagggccac tcctggtgga gaaccctcgt gactactcca ctgaattaag     2460

tgtcaccatc gccgtggggg cctccctcct gttccttaac gttctggcct tcgctgccct     2520

ctactaccgt aaggacaaac ggcgccagga gcccctgcgg cagcctagcc ctcagcgggg     2580

agccggggcc ccggagttgg gagctgctcc agaggaggag ctggcagcat tacaactggg     2640

ccccacccac cacgagtgtg aggccggtcc cccccatgac acgctgcgcc tcactgcatt     2700

gcccgactac accctgaccc tgcggcgctc cccggatgac atcccactca tgacccccaa     2760

caccatcact atgatcccca actccctggt agggctgcag acattgcacc cctataacac     2820

ctttgccgca gggttcaaca gtaccgggct gccccactca cactccacta cccgggtata     2880

gctccaactc agagcacagc caatctccag gctccctccc tcccagatcc aggaacacat     2940

gcacacacac acacacacac acgcagacac acacacacac acacatatat gtatacgcac     3000

gcacccacac cctacagcag atccacctgc acaaacatag acagatgtgg acatgcaccc     3060

gcatgtacaa aaacacaaat acggaagtaa acctgaacaa accctttaaa tggggacgca     3120

gatgagtcct cggtaaaccg aggacccatg aaacagcagc tgaagccagc tccctgaatc     3180

tgaccacaga cactcctggg gggcctgaaa gcaacagctg gacaccccct tggtgctcgc     3240

cttcggcctc tcttggaact gcaccaccga ccaactccag acttgggagc tttaaagagc     3300

aggatagctc ttcctcccca ggacttggtc ttttttctgg gtcttgtttt gttgattttt     3360

cttttttaat tttggaacaa atgcttttcc aacccatgag tgctaagagc ctctggaagg     3420

gagggcttca ggcccgaagg tctctctggc tctaggaccc ccagtgctca cacaatcaga     3480

ccaaggaaca agacccccag gaaggaaaca gatttaagca agaccatggg gtggaaggag     3540

aaaggggcta gcactggatg gagctggagg gtcgtagggg agagatctcc aactctctct     3600

gtgtccgtgt ggagggctgc agagcctgca gggtgacctg cttccccaaa ggccaacagc     3660

attggcctgg ccagaccagg tgaccttaga tttggtgaac aacgtactat ggaagccaca     3720

tcactattgg gcccccaggt ctgatctggg ttttgcctct gcccttgggg aaatgctatc     3780

agaaattcgc cccattttct ttacagtctt ttgtgtctgt catttctctt tcaaaaaggc     3840

ggtgtttttt gttgttgttg gttttttttt ttttttaaag aaaagttctt aaaacactaa     3900

cggaaaccca tggagtttgt cctttgtaaa aattttaaac acagtgtctt gatataaaaa     3960

taaaaaatcc agttagcact cccaaaaaaa aaaaa                                3995


<210>  171
<211>  3935
<212>  DNA
<213>  homo sapiens

<400>  171
ccctcggtgc gcgggcacag cagccaggct gccggagagc tgatctcggg gattcgggtg       60

cggagccctt ggcctggagg cgatatgggt ggtccgtggc ccggttcagt cgcttgcagc      120

agcccgggga acaggcctgt ctggccctga gggagtcccc tttctgaagc tgtggtgctt      180

ggacgacctg ctctctacat tgctgggcac ctgtaggtgt ccctcgagag ctcagttttg      240

aggttcaagt cagtgtggcc atgaaggggc tgcctattgg gctgatgctg tgaccctgga      300

gtctgcctct cctgccagtc cccctgcccg gaacatgtgg ctgcggcttg gcccgccctc      360

gctgtccctg agccccaagc ccacggttgg caggagcctg tgcctcaccc tgtggttcct      420

cagtttggcg ctgagggcca gtacccaggc cccagcaccc acagtcaaca ctcactttgg      480

gaagctaagg ggtgcccgag taccactgcc cagtgagatc ctggggcctg tggaccaata      540

cctgggggtg ccctacgcag ctcccccgat cggcgagaaa cgtttcctgc cccctgaacc      600

acccccatcc tggtcgggca tccggaacgc cacacacttt cccccagtgt gcccccagaa      660

catccacaca gctgtgcccg aagtcatgct gccggtctgg ttcactgcca acttggatat      720

cgtcgctact tacatccagg agcccaacga agactgtctc tacctgaacg tctatgtgcc      780

gacggaggat ggatccggcg ctaagaaaca gggcgaggac ttagcggata atgacgggga      840

tgaagatgaa gacatccggg acagtggtgc taaacccgtc atggtctaca tccacggagg      900

ctcttacatg gaagggacag gcaacatgat tgatggcagc atcctcgcca gttatggcaa      960

tgtcatcgtc atcaccctca actatcgggt tggagtgcta ggtttcctga gtactggaga     1020

tcaggctgcc aagggcaact atgggctcct tgaccagatc caggccctcc gctgggtgag     1080

cgagaatatt gccttcttcg ggggagaccc ccgccggatc actgtctttg gctcgggcat     1140

tggtgcatcc tgcgtcagcc tcctcacgtt gtcacatcac tcagagggac ttttccagag     1200

agccatcatc caaagtggct ctgctctgtc cagctgggct gtgaactacc aaccagtgaa     1260

gtacaccagc ctgctggcag acaaagtggg ctgtaatgtg ctggacaccg tggatatggt     1320

ggactgtctt cggcaaaaga gtgccaagga gctggtagag caggacatcc agccagcccg     1380

ctaccacgtg gcctttggcc ctgtgattga tggtgatgtc attcctgatg accctgagat     1440

cctcatggag cagggcgagt tcctcaacta tgacatcatg ctaggtgtca accagggcga     1500

gggtctcaag tttgtggaag gggtggtgga ccctgaggat ggtgtctctg gcactgactt     1560

tgactattcc gtctccaatt ttgtggacaa tctgtatggc tatcctgagg gtaaggacac     1620

cctgcgagag accatcaagt tcatgtatac agactgggca gaccgtgaca accctgagac     1680

ccgccgtaaa acactggtgg cactcttcac tgaccaccag tgggtggagc cctcagtggt     1740

gacagccgat ctgcatgccc gctacggctc gcctacctac ttctacgcct tctatcatca     1800

ctgccagagc ctcatgaagc ctgcttggtc agatgcagct catggggatg aagtacccta     1860

tgtttttggg gttcctatgg taggccccac tgaccttttc ccctgcaact tctccaagaa     1920

tgatgttatg ctcagtgctg tcgtcatgac ctattggacc aactttgcca agactgggga     1980

tcccaacaag ccggtccccc aggacaccaa gttcattcac accaaggcca accgctttga     2040

ggaagtggcc tggtccaaat acaatccccg agaccagctc taccttcaca tcgggctgaa     2100

accaagggtc cgagatcatt accgggccac taaggtggcc ttttggaaac atctggtgcc     2160

ccacctatac aacctgcatg acatgttcca ctatacgtcc accaccacca aagtgccgcc     2220

tccggatacc acccacagct cccacatcac ccgcaggccc aatggcaaga cctggagcac     2280

caagcggcca gccatctcac ctgcctacag caacgagaat gcccaggggt cctggaacgg     2340

ggaccaggat gcagggccac tcctggtgga gaaccctcgt gactactcca ctgaattaag     2400

tgtcaccatc gccgtggggg cctccctcct gttccttaac gttctggcct tcgctgccct     2460

ctactaccgt aaggacaaac ggcgccagga gcccctgcgg cagcctagcc ctcagcgggg     2520

agccggggcc ccggagttgg gagctgctcc agaggaggag ctggcagcat tacaactggg     2580

ccccacccac cacgagtgtg aggccggtcc cccccatgac acgctgcgcc tcactgcatt     2640

gcccgactac accctgaccc tgcggcgctc cccggatgac atcccactca tgacccccaa     2700

caccatcact atgatcccca actccctggt agggctgcag acattgcacc cctataacac     2760

ctttgccgca gggttcaaca gtaccgggct gccccactca cactccacta cccgggtata     2820

gctccaactc agagcacagc caatctccag gctccctccc tcccagatcc aggaacacat     2880

gcacacacac acacacacac acgcagacac acacacacac acacatatat gtatacgcac     2940

gcacccacac cctacagcag atccacctgc acaaacatag acagatgtgg acatgcaccc     3000

gcatgtacaa aaacacaaat acggaagtaa acctgaacaa accctttaaa tggggacgca     3060

gatgagtcct cggtaaaccg aggacccatg aaacagcagc tgaagccagc tccctgaatc     3120

tgaccacaga cactcctggg gggcctgaaa gcaacagctg gacaccccct tggtgctcgc     3180

cttcggcctc tcttggaact gcaccaccga ccaactccag acttgggagc tttaaagagc     3240

aggatagctc ttcctcccca ggacttggtc ttttttctgg gtcttgtttt gttgattttt     3300

cttttttaat tttggaacaa atgcttttcc aacccatgag tgctaagagc ctctggaagg     3360

gagggcttca ggcccgaagg tctctctggc tctaggaccc ccagtgctca cacaatcaga     3420

ccaaggaaca agacccccag gaaggaaaca gatttaagca agaccatggg gtggaaggag     3480

aaaggggcta gcactggatg gagctggagg gtcgtagggg agagatctcc aactctctct     3540

gtgtccgtgt ggagggctgc agagcctgca gggtgacctg cttccccaaa ggccaacagc     3600

attggcctgg ccagaccagg tgaccttaga tttggtgaac aacgtactat ggaagccaca     3660

tcactattgg gcccccaggt ctgatctggg ttttgcctct gcccttgggg aaatgctatc     3720

agaaattcgc cccattttct ttacagtctt ttgtgtctgt catttctctt tcaaaaaggc     3780

ggtgtttttt gttgttgttg gttttttttt ttttttaaag aaaagttctt aaaacactaa     3840

cggaaaccca tggagtttgt cctttgtaaa aattttaaac acagtgtctt gatataaaaa     3900

taaaaaatcc agttagcact cccaaaaaaa aaaaa                                3935


<210>  172
<211>  1634
<212>  DNA
<213>  homo sapiens

<400>  172
ggcgcggtac aggagcagca ctgccggcgg gggcgggtgc cagggacttg gaggtggagg       60

ggacgcggcg gtactctggc gtcttccgac ttcgactcct taccttaaaa gatgctggag      120

tcatatgtaa ctccaatttt aatgagctat gtgaatcgct acatcaagaa cttaaagccg      180

tcggatctac agctttcact atggggtgga gacgtggtac tcagcaagct cgagttaaag      240

ttggatgtgc tggaacagga actgaaatta ccattcactt ttttaagtgg acatattcat      300

gaattgagga ttcatgtacc atggacaaaa ctgggttcag aaccagtggt aattaccatc      360

aatactatgg aatgcatttt gaaacttaag gatgggatac aggatgacca tgaaagctgt      420

ggttctaatt ctaccaaccg tagtactgct gagagcacaa aatcatcaat caaaccgcgg      480

agaatgcagc aggctgctcc tacagatcct gacttaccac caggttatgt gcagagtctg      540

attagacgag ttgtaaataa tgtaaacatt gtgataaata atctcatact aaaatatgtt      600

gaagatgata tcgtcctttc cgtcaatatc acttctgcag aatgttatac agtaggtgaa      660

ttatgggatc gtgcattcat ggatatttct gcaactgatt tggtgctgag aaaggttatc      720

aatttttctg actgtacagt ttgtcttgat aaacggaatg ccagtggtaa aatagaattt      780

taccaggatc ctttattata caaatgttcc ttcagaactc gtcttcattt tacatatgaa      840

aacctaaatt ccaagatgcc atctgttatt aaaattcata ctttagtgga aagtttgaaa      900

ctttctatca cagatcaaca actgcctatg tttattcgta taatgcaact tggaattgct      960

ctttactatg gagaaatagg caattttaaa gaaggcgaaa tagaggacct tacttgtcat     1020

aataaagata tgctaggaaa cattacaggt tctgaagatg aaacaagaat agatatgcaa     1080

tatcctgctc agcataaagg tcaagagtta tattcacagc aagatgagga gcagccacag     1140

ggatgggtgt catgggcctg gtcctttgtg cctgcaattg tgagttatga cgatggcgag     1200

gaagactttg ttgggaacga tcctgcatca accatgcatc aacaaaaagc acagactttg     1260

aaggatccta ttgtttctat aggattttat tgcacaaagg caacggtgac tttcaaagta     1320

ggtcttttct cttgctgttt atatctctat caactttaat gcttaaattt ggattgttag     1380

tacaattcta gctttattca agtttgcttt gcattcagta gatgtgagat agagtctaac     1440

agttcttact tcataaaatt acatggctcc tccacttgaa atctttgaat tctgatccct     1500

tcctgtcttc ttagggcatt ctccacattt cttttttatt agcttcatgg atagtttttt     1560

gccctattga atcattcagt tggtgtacaa acatgcctta atattgtcat taaaaaagaa     1620

aggaacagca aaaa                                                       1634


<210>  173
<211>  14025
<212>  DNA
<213>  homo sapiens

<400>  173
ggcgcggtac aggagcagca ctgccggcgg gggcgggtgc cagggacttg gaggtggagg       60

ggacgcggcg gtactctggc gtcttccgac ttcgactcct taccttaaaa gatgctggag      120

tcatatgtaa ctccaatttt aatgagctat gtgaatcgct acatcaagaa cttaaagccg      180

tcggatctac agctttcact atggggtgga gacgtggtac tcagcaagct cgagttaaag      240

ttggatgtgc tggaacagga actgaaatta ccattcactt ttttaagtgg acatattcat      300

gaattgagga ttcatgtacc atggacaaaa ctgggttcag aaccagtggt aattaccatc      360

aatactatgg aatgcatttt gaaacttaag gatgggatac aggatgacca tgaaagctgt      420

ggttctaatt ctaccaaccg tagtactgct gagagcacaa aatcatcaat caaaccgcgg      480

agaatgcagc aggctgctcc tacagatcct gacttaccac caggttatgt gcagagtctg      540

attagacgag ttgtaaataa tgtaaacatt gtgataaata atctcatact aaaatatgtt      600

gaagatgata tcgtcctttc cgtcaatatc acttctgcag aatgttatac agtaggtgaa      660

ttatgggatc gtgcattcat ggatatttct gcaactgatt tggtgctgag aaaggttatc      720

aatttttctg actgtacagt ttgtcttgat aaacggaatg ccagtggtaa aatagaattt      780

taccaggatc ctttattata caaatgttcc ttcagaactc gtcttcattt tacatatgaa      840

aacctaaatt ccaagatgcc atctgttatt aaaattcata ctttagtgga aagtttgaaa      900

ctttctatca cagatcaaca actgcctatg tttattcgta taatgcaact tggaattgct      960

ctttactatg gagaaatagg caattttaaa gaaggcgaaa tagaggacct tacttgtcat     1020

aataaagata tgctaggaaa cattacaggt tctgaagatg aaacaagaat agatatgcaa     1080

tatcctgctc agcataaagg tcaagagtta tattcacagc aagatgagga gcagccacag     1140

ggatgggtgt catgggcctg gtcctttgtg cctgcaattg tgagttatga cgatggcgag     1200

gaagactttg ttgggaacga tcctgcatca accatgcatc aacaaaaagc acagactttg     1260

aaggatccta ttgtttctat aggattttat tgcacaaagg caacggtgac tttcaaactc     1320

acagaaatgc aagttgagag tagttattac agtccacaga aagtaaaatc taaagaagta     1380

ttgtgttggg aacaagaagg aactacagtt gaggccctta tgatgggaga acctttcttt     1440

gattgccaga ttgggtttgt tggttgcaga gccatgtgcc ttaaaggaat tatgggtgtt     1500

aaagattttg aagagaatat gaatagaagt gaaactgaag cctgtttctt catttgtggt     1560

gacaatttga gtacgaaagg tttcacatac cttacaaatt cattgtttga ttaccgaagc     1620

ccagaaaata atggtactcg cgcagaattt atcttggatt caactcatca taaggagaca     1680

tacactgaga tagctggaat gcaacggttt ggggcttttt atatggatta cctgtataca     1740

atggagaaca ctagtggcaa aggttccaca aatcaacaag acttttcttc agggaaaagt     1800

gaagatttgg gaacagttca ggagaagtcc accaaaagcc ttgttatagg tcctcttgat     1860

tttcgtttgg atagcagtgc ggtgcatagg attttgaaaa tgattgtgtg tgccttggaa     1920

catgaatatg aaccatatag caggctaaaa tcagatatta aggatgaaaa tgaaacaata     1980

ctgaatcctg aagaggtggc tcttctggag gaatatattc ctactcgaca tacaagtgtt     2040

actctcctca aatgtacctg cacaatttcc atggctgaat tcaacttgct ggaccattta     2100

ctacctgtca ttatgggaga aaagaactca agtaacttca tgaatactac aaacttccag     2160

tctcttcggc ctttgccatc cattcgaata ttggtggata aaattaatct ggaacattca     2220

gtgccaatgt atgctgaaca gttggtgcat gtggtcagca gccttactca accttctgat     2280

aacctgcttc attattgtta tgtacactgc tatcttaaga tatttggttt ccaggcagga     2340

ctgacgtctt tggattgcag tggatcttac tgcttacctg taccagttat tccctctttc     2400

agcactgctc tttatgggaa acttctgaaa ctccccacat gctggaccaa aagatctcag     2460

attgctataa ctgaaggtat atttgaactt ccaaatctca caattcaagc tacaagagca     2520

cagacacttc tcttgcaagc aatatatcaa agttggtctc atcttggaaa tgtcagctct     2580

tccgcagtga ttgaagcttt gataaatgaa atcttcctaa gtataggtgt gaaatctaag     2640

aatcccctgc caactcttga gggctcaatc cagaatgttg aattgaagta ctgcagcaca     2700

tcattggtca aatgtgcctc tgggaccatg ggatcaataa aaatttgtgc caaagcccca     2760

gttgatagtg gaaaagagaa gttgattccc ttgcttcagg gtccttctga cactaaagac     2820

cttcatagca ccaagtggct caatgagagt agaaagccag agtctctctt agctccagat     2880

ttgatggcct tcacaatcca agttccacaa tatattgact actgccacaa ttccggtgct     2940

gtacttcttt gcagtataca aggactagca gttaatattg acccaatctt atatacgtgg     3000

ctcatctatc agcctcagaa acgaacaagt agacatatgc aacagcagcc tgtggtagct     3060

gttcctcttg ttatgccagt ttgtagaagg aaagaggatg aggtgtctat tggaagtgcc     3120

cccttggcaa agcagcaatc atatcaggcc tctgaatatg ccagcagccc tgtaaaaaca     3180

aaaacggtaa cagaatcccg cccattgtca gttcctgtta aagccatgtt gaatatatct     3240

gaaagctgta gaagtcctga agaaagaatg aaggaattta ttggaattgt ttggaatgca     3300

gtgaagcatc tcacactaca gcttgaagta caatcttgtt gtgtgtttat tccaaatgat     3360

agcctgcctt ccccaagtac aattgtatct ggtgacattc ctggaacagt aagaagttgg     3420

taccatggac aaaccagcat gccgggaaca cttgtcctct gtttgcctca aataaagatt     3480

attagtgctg ggcacaagta tatggaacct ctgcaggaga ttccatttgt tatcccacga     3540

cccatccttg aagaaggtga tgcttttcct tggacgatca gcttgcataa tttcagcata     3600

tatacccttc ttggaaaaca agtgacactt tgcctagtgg aacctatggg ttgcacctcc     3660

actctagctg tcacgtctca aaaactgctt gctacgggac ctgatacacg acattcattt     3720

gttgtctgtc tccatgttga cctagagtca ctagagataa aatgctctaa tccccaggtc     3780

cagctcttct atgaactaac tgatatcatg aataaggtct ggaacaagat tcagaagaga     3840

ggcaatctca acctatctcc aacctctcca gagaccatgg cagggcctgt tcctacttct     3900

ccagttagaa gcagtatagg cacagctcct ccagatacca gcacatgcag cccatctgct     3960

gacattggga ctactactga gggagattct atacaagcag gtgaggaatc accattctca     4020

gattctgtga ccttggaaca aactacaagt aatattggag gaaccagtgg acgtgttagt     4080

ttatggatgc agtgggtgct tcccaaaatt actataaagc tctttgctcc agatcctgaa     4140

aataaaggca cagaggtttg tatggtcagt gaactagaag atctcagtgc ttccatagat     4200

gtccaggatg tatataccaa agtgaaatgt aaaatagaga gtttcaatat tgatcactat     4260

agaagcaggc caggggaagg ttggcagtca ggacattttg aaggagtatt tctacaatgc     4320

aaagaaaaat ctgtgacaac tacaaaactt ctagatggca ctcatcagca gcatggattc     4380

ctctctctga catacacaaa agctgtaaca aaaaatgtcc gccacaagtt aacatcaaga     4440

aatgagcgaa gaagttttca taagttatct gaaggcctaa tggatggttc tcctcatttt     4500

cttcatgaaa ttcttctttc agcacaagct tttgatattg ttctttattt tcctttactt     4560

aatgccattg caagtatatt tcaagcaaaa ctaccaaaga cccaaaaaga gaaaagaaaa     4620

tctcctggtc agcccatgag gacccataca ctgacatccc gcaatttacc tttgatttat     4680

gtcaacacaa gtgtaatcag aatttttatt ccaaaaacag aagaaatgca gccaactgtt     4740

gaagctaatc aggcagcaaa agaagacact gtggttttga agattggctc tgttgccatg     4800

gctccccagg ctgacaatcc ccttggcaga tctgtcctta ggaaagatat ttaccagaga     4860

gccttgaact taggaattct tcgagatcct ggatcagaaa tcgaagacag acaataccaa     4920

atagatctgc agtccatcaa tattggtact gcacagtggc atcaactaaa accagagaag     4980

gaaagtgtct caggaggggt ggtaacagag actgaaagga attctcaaaa tccagccctt     5040

gagtggaata tggccagcag catacggcgg catcaagaaa ggagagcaat tttgaccccc     5100

gttttgacag atttttctgt ccgaataact ggagcacctg ctgtcatttt caccaaagta     5160

gtttctccag aaaatttgca tactgaggag attttagtgt gtggccattc cttagaagtg     5220

aatataacca caaacctgga cttcttccta agtgtggctc aagttcaact cttacatcag     5280

ttaatagtag caaatatgac tggactggaa ccatcaaaca aggctgcaga gatctctaaa     5340

caagaacaga aaaaagtgga tatatttgat ggaggcatgg ctgaaacctc atctcgctac     5400

agtggtgctc aggatagtgg aattggcagt gacagtgtta aaatcagaat agtgcaaata     5460

gagcagcaca gtggtgccag tcagcatcgc attgcccgtc cctcacgcca gtcatcaatt     5520

gtaaaaaatc taaattttat tccctttgac atatttatta ctgcaagtag aatctcacta     5580

atgacctatt cctgtatggc cttatccaaa tcgaaatcac aagaacagaa gaataatgaa     5640

aaaacagaca agagttcatt aaatctccca gaagttgatt cagatgttgc taagcccaac     5700

caggcatgta tttccacggt gacagcagaa gatctcttaa ggagcagcat ttcttttcct     5760

tcagggaaaa aaataggggt cctctctctt gaaagtcttc atgcatccac aaggtcatct     5820

gctagacaag cacttggtat aactattgtt cggcagcctg gtcgaagagg aactggtgac     5880

ttacagctag agccttttct gtactttatt gtgtcccagc cttccttgct tctgagttgt     5940

caccacagaa agcagcgagt ggaagtatcc atttttgatg ctgtgcttaa aggggtggcc     6000

tctgattaca aatgtataga tcctgggaag actctgcctg aagcccttga ttattgcact     6060

gtttggctac agacagtgcc tggagaaata gacagcaaaa gtggtattcc accttccttt     6120

ataacactac agattaaaga ctttctgaat ggaccagcgg atgtcaattt ggatatatca     6180

aagcctttga aagcaaacct gagtttcacc aaactggatc agataaacct ttttttaaag     6240

aagataaaaa atgcacacag tttggcacat agtgaagaga cttcagccat gtccaacacc     6300

atggtgaata aggatgatct tccagtctcc aaatattacc gtggaaagtt gtctaaaccc     6360

aaaattcatg gtgatggagt gcaaaagatt tcagctcaag aaaacatgtg gagagctgtt     6420

tcctgctttc aaaaaatttc tgttcaaact actcagattg tgatctccat ggaaactgta     6480

ccccatacca gcaaaccatg cctgttagca tctctctcaa acctcaatgg aagccttagt     6540

gtcaaggcaa cacaaaaagt acctggcata attcttgggt catcatttct actcagtata     6600

aacgattttc tccttaaaac aagtctcaaa gaaagaagcc gcattctgat aggaccatgt     6660

tgtgctactg ccaatctgga agctaagtgg tgtaaacaca gcgggaatcc aggcccagaa     6720

caatccatac caaaaatatc cattgactta agaggaggtc tactacaggt cttctggggt     6780

caagaacatt tgaattgttt agttcttcta catgaattac tcaatggata ccttaatgag     6840

gagggaaatt ttgaagtaca agtttctgaa ccagtgcctc aaatgtcatc tcctgtggaa     6900

aagaatcaga catttaaaag tgaacaaagt tcagatgacc tacggacagg tctatttcag     6960

tatgtacagg atgctgaatc tttgaaattg cctggggtct atgaagtctt attttataat     7020

gaaactgaag attgcccagg gatgatgtta tggagatatc cagaacctag agtactcacc     7080

cttgtacgaa taactcctgt accttttaac accacagagg atccagatat tagcacagca     7140

gaccttggtg atgtgctaca ggttccttgt agcttggaat actgggatga actccagaag     7200

gtttttgttg catttagaga atttaatctg tctgaaagca aagtttgtga actgcagttg     7260

ccggatatca atctcgtgaa tgaccagaag aaattagtat cttcagatct ttggagaatt     7320

gtcttgaaca gcagtcaaaa tggagctgat gaccaaagct ctgcaagtga gtctggttct     7380

caaagcactt gtgatccact tgtgactcca acagccctgg ctgcctgtac cagagttgac     7440

tcctgcttta ccccatggtt tgtcccatcc ctttgcgttt ctttccagtt tgctcacctg     7500

gaattccatc tttgtcatca ccttgaccaa ctaggcacag ctgcaccaca gtacctacag     7560

ccatttgttt ccgacagaaa tatgccatct gaactagaat acatgattgt ttccttcaga     7620

gaaccacaca tgtatcttcg acagtggaat aatggttctg tctgtcagga gatccagttc     7680

ttagctcaag cagactgtaa acttctagag tgcagaaatg tcactatgca aagtgtggtg     7740

aaacccttca gcatcttcgg gcagatggca gtttccagcg atgtagtgga aaagctgctt     7800

gactgcaccg tgatagttga ttctgtattt gtaaaccttg gacagcatgt agtccattca     7860

ctaaacactg caatacaagc ttggcaacag aacaaatgcc ctgaggtaga ggagttggtc     7920

ttcagccatt ttgtgatctg taatgacaca caggagacac tgcggtttgg ccaggtggat     7980

actgatgaaa atattctgct ggcgagtctc cacagtcacc agtacagctg gcgctctcac     8040

aaatccccac agctgttaca catctgtatt gaaggttggg gcaactggcg ttggtcagag     8100

cctttcagtg tggaccatgc cgggactttt attagaacaa ttcagtacag gggtcgaact     8160

gcttctctca tcatcaaggt tcagcaactc aatggagtac aaaaacagat tatcatctgt     8220

ggaagacaga tcatctgtag ttacttgtct caaagcatag aactaaaagt cgttcagcat     8280

tacattggtc aagatggaca agctgtagtt cgggaacatt ttgactgcct cacagccaaa     8340

cagaaattgc cttcgtacat actagaaaac aatgaactga cggagctgtg tgtgaaggcc     8400

aaaggagatg aagactggtc aagagatgtg tgcctggaat ccaaagcccc tgagtacagc     8460

attgtcattc aggtgccatc ttcaaacagt tccattattt atgtctggtg cacagttttg     8520

actttagaac ccaactctca agtgcaacaa cgaatgattg tgttcagccc tctttttatc     8580

atgaggagtc atcttccaga ccccattatc atacatttgg agaaaaggag tctgggattg     8640

agtgaaacac aaattattcc aggaaaaggg caggaaaaac cactgcaaaa catagaacct     8700

gaccttgtac atcacctgac attccaagca agagaagaat atgatccttc agattgtgca     8760

gttcccatct caacatccct cattaagcaa atagccacta aggtacaccc tggaggcaca     8820

gttaatcaga tccttgacga attctatggg ccagaaaagt cgcttcaacc catatggccc     8880

tataataaga aggattctga caggaatgaa cagctaagtc agtgggatag cccaatgcga     8940

gtgaagctgt caatctggaa gccatatgtt agaactttgt tgatagaact tctgccctgg     9000

gccctgctta tcaatgaatc caaatgggac ctctggctat ttgaaggaga gaaaattgtt     9060

ctacaggttc ctgctggcaa aattattatt cctcctaatt ttcaggaagc ttttcaaatt     9120

ggaatatact gggcaaatac aaacactgtg cacaagtcag tagcaattaa actggtccat     9180

aacctgacat ctccaaagtg gaaagatgga ggtaatggtg aagttgtgac actggatgaa     9240

gaagcgtttg ttgatactga aataagactt ggtgcttttc caggacatca gaagttatgt     9300

cagttctgca tttcctccat ggtacagcaa ggtatacaaa ttattcagat tgaagacaag     9360

actacaataa tcaataatac accatatcaa atattttata aaccacagct atctgtctgc     9420

aatccccatt ctggaaagga gtattttcgt gttccagaca gtgctacttt tagcatttgc     9480

ccaggtggag agcagcctgc tatgaaatcc agctcccttc cttgctggga cttgatgcct     9540

gacatcagtc agtcagtact ggatgcatcc ctgcttcaga aacagatcat gctgggcttt     9600

tctcctgccc caggtgctga cagctcacag tgctggagcc tgccagctat agttagacca     9660

gagtttccca gacagagtgt ggcagtaccc ctcgggaatt tccgggaaaa tggattctgt     9720

accagggcta tagtgctgac atatcaagaa cacctcggag tgacttattt aaccctctca     9780

gaagacccta gtcctcgagt aattatccac aatagatgtc cagtaaaaat gcttataaag     9840

gaaaacatta aagatattcc aaagtttgag gtttattgca aaaaaattcc ctccgagtgc     9900

tcaattcatc atgagctgta tcatcagatt tccagttatc cggactgcaa gaccaaagac     9960

ttacttccaa gcctactttt gagagttgaa cctctagatg aagtaacaac tgagtggagt    10020

gatgccattg acatcaacag tcagggaaca caggttgtgt tcctgactgg ctttggctat    10080

gtgtatgtgg atgttgtaca tcagtgtggc acagtcttca tcactgtggc cccagaagga    10140

aaagcaggac ctattttaac caataccaac agagcgccag agaagattgt tacatttaaa    10200

atgttcatca ctcagttaag cctggcagtg tttgatgacc tcacccacca caaagcatca    10260

gctgagcttc tgagactcac actggacaac atttttctct gtgtggcccc gggagctggt    10320

cccctccctg gggaagagcc tgtggctgcg ttgtttgaac tttactgtgt ggagatctgc    10380

tgtggggacc tgcagctaga caaccagctt tataacaagt ccaatttcca ctttgctgtc    10440

ttagtctgcc agggagaaaa agcagaaccc attcagtgtt ccaaaatgca gagtctcctc    10500

atatccaaca aagagttgga agaatacaag gaaaaatgtt ttatcaaact ttgcatcacc    10560

ttaaatgaag gcaagagcat cctctgtgat attaatgagt tcagctttga attaaaacct    10620

gctcggttat acgtggaaga cacatttgta tactacatca agactttgtt tgacacctac    10680

cttcctaaca gcaggttggc tggtcactcc acacacctct ccgggggtaa acaggtgttg    10740

cccatgcagg tcacacagca cgccagggcc ttggtgaatc ctgtgaagtt acggaaactg    10800

gtgatccagc cagtaaattt gctcgtcagc atccacgctt ccctcaagct gtacatagcc    10860

tcagaccaca ctcctctctc cttctcggtg tttgaaagag gacccatctt caccactgcg    10920

aggcagcttg tgcacgccct ggcaatgcac tatgccgctg gggccctttt tagagcaggc    10980

tgggtagttg ggtctctgga tattcttggc agccctgcaa gcctggtgag aagcatcggg    11040

aacggggtcg ccgacttctt caggcttccg tatgaggggc tgacccgggg ccctggagcc    11100

ttcgtgagtg gcgtctccag agggaccaca tcgtttgtaa agcacatctc caaaggtacc    11160

ctcacatcca tcaccaacct cgccacaagc ctggcccgga acatggaccg gctctcactg    11220

gatgaggagc actacaaccg gcaggaggag tggcggcggc agctccccga gagcctgggc    11280

gaggggcttc gacagggcct gtcccggctg ggcatcagcc tgcttggtgc aattgctggt    11340

atagttgatc agccgatgca gaacttccag aaaacatctg aggcacaggc ttcagcagga    11400

cacaaggcca agggtgtcat ctcgggtgtg gggaaaggaa tcatgggggt gttcacaaag    11460

cccatcggag gagctgctga gctggtgtca cagactggct atggtatttt acatggagct    11520

ggactttctc agcttcccaa acagcgccat cagccaagtg atctacatgc tgaccaggct    11580

ccaaacagcc atgtcaaata tgtctggaaa atgcttcagt ctctgggcag accagaagtc    11640

cacatggccc tggacgtggt tctggtgagg ggctcaggcc aggagcatga agggtgcttg    11700

ctgctgacat cagaagtgct cttcgtggtg agtgtcagtg aggacacaca gcagcaggcc    11760

ttccccgtca cagaaatcga ctgtgcacag gacagcaagc agaacaactt actcacagtg    11820

cagctcaagc agccaagagt ggcctgtgat gtggaggtag atggagtccg agagagactg    11880

tcagagcaac agtacaacag actggtggac tacatcacaa agacatcttg tcacctggcc    11940

cccagctgtt cttccatgca aataccatgc cctgtggtgg ctgcagaacc tcccccctcc    12000

actgttaaaa cataccatta cctggttgat ccacattttg ctcaggtctt ccttagtaaa    12060

tttaccatgg tgaaaaataa agccctgagg aaagggtttc cttgagtccc ctctgaggtg    12120

tttattcctg cttgtgtgat ttagtttttg ggtttctttg agacagggtc tcactgcatt    12180

gcccttgctg acctcaaatt ctggggttca agcaatcctc ccacctcaac ccacaagtag    12240

ctacgactgc aagcacctgc caccataaag ggctgcattt tgccaccata aagggctgca    12300

tttttttaaa aagcctaggc agctctaaca tcatctgata tggacacaag gccaacagtt    12360

tccttattta catccttacc tctaaaagat acttcaaagt gacaaaaacg tgttccttcc    12420

ccacttagag acaatgatta acagggccct atatgttctt accacataca gaggatgcat    12480

ttatttttgc tctatgacac ttgcaaaaat ctctactgta attaatttgg gtctattatt    12540

aactctctgt tccatcatag aatgtggcca ggccttacaa tggagagcca gagttaaaac    12600

ttcaagttgc atctgttttt gggctgagtc accacctttg cctcatgctc ctttgtctgc    12660

aaaggcctag gattctttct ttaaatgaaa tgcttaggac tttgtggctt gttacatttg    12720

tcatttaact gcagtgctat tctttgaaag ctgctatgtg tattttctct gaagtctgca    12780

ttttactaaa atttacaaca gtctgatgat tgattgatta ctgtccaggt acattttaga    12840

aaaagtgttc ttcttccagt ttgttttact aagcaaactt tgagtaaatc ctttgtccta    12900

tattgaatcc agtcccaaag tgttcaggtg agtttctcta gttccataaa caaaacatac    12960

atagtgggaa ctccctggta tgccatagag cacacaagaa ccccaatatt aatgctaaca    13020

attataccag tccattttgt ttattctgtg gaattgactt gacaaagcat gaagatattc    13080

ccagtgtctg tctgataata ttttgcatct aagaatgggt ttgactcaag atcttgggtt    13140

accaagatgt cttaaatgtt cagtaaatat ctttcttaca gtccagtagc ttagagcatg    13200

tttgctgatt gatattacat ttaaacttgg ggctacagct tgttacctag aattttgaga    13260

tactaagaga atgcaatttt aaatgcccac tggttttatt tgttttggag agagggtctc    13320

attctgtcac ccaggctaga gtacagtggg aacagtcatg gctcactgca gcttaagctc    13380

actgcctggg ctcaagtgat cttactccag cctcccaagc agctgggact acaccaccac    13440

aggtatgcac caccatacct ggctgatttt taaaattttt tctagagatg aggtctcact    13500

atgttgccca gctggtctca tactcctcag ttcacgcatt cctcccacct ccacctccca    13560

aactgctggg attacaggtg tgagccacca tgcccaacac ccactgatct ttaactctca    13620

catgttgggc ataagaagtc actatataat tgttactgga aagcaagact taacgaacaa    13680

ttctgactat gaaaaatgtc tctttcagtt tgttctgtaa atatttagaa aagtgacagc    13740

tgtcaacctc agagtaacta tttctaaaaa tgtaaatatg tattaatcct tgtatctttt    13800

atggtaattt tgcatattga tatgaattat ataaaattgt ttaaaataaa aggtgtcctt    13860

gaattactga ccacccatag atgtctactg ttaccaggtt ttacaatgca aattttcact    13920

aatacctggg tttaatacag ctcacatcac tgaatgttac acatgagttt aaatgggtaa    13980

tatacaggtt ttgttataat aaagttactg attaaattag ctttg                    14025


<210>  174
<211>  3747
<212>  DNA
<213>  homo sapiens

<400>  174
gggcctactc tgccgccgcc gccgcccgcc cgctccagcc gccgccgccg ccgccaccgc       60

cctccaggct ccgggacccg gcccgcgcca ccgcccccgt gcgcgccccg ccgccgccgc      120

cttcgccttc gccttttgtt tcctccgctc cggcgccccc gccccggctc gcgctttgca      180

ggggacgcag cgcgcgcccc cagcgggccc gggaaaagcc gcggcgcgcg cgcgcgcctg      240

cgcggcggac ccctccttct cctccccgcg tgcgcgtgcc cttcttggct gcgcgccggc      300

gccgcctggc gggcgggagg ggaggtggca ggcgcgtttg caggaggggc gcacctcttc      360

gctcgcgcac ccccccggaa ggtagaccgg gaaggggagg cgggcgggcg gagaggagag      420

agtggcgcgc agtccagcga gggcgggggt tggctatgtg gggggtggtg caccccgcag      480

tctagacagt ctgatccggg ctgggggcgt gtacactcgg cgcacctgcg agactacaga      540

gcctcgggcc ggcacgtgtg gggagtgtgg acacgtctgc tgcgccccgc ttctcgctgc      600

tgaggggaag ggagggggcg ggcaggtgca gcggccgggc tagtgggagg gggcggcggc      660

catggagcgg gtgaacgacg cttcgtgcgg cccgtctggc tgctacacat accaggtgag      720

cagacacagc acggagatgc tgcacaacct gaaccagcag cgcaaaaacg gcgggcgctt      780

ctgcgacgtg ctcttgcggg taggcgacga gagcttccca gcgcaccgcg ccgtgctggc      840

cgcctgcagc gagtactttg agtcggtgtt cagcgcccag ttgggcgacg gcggagctgc      900

ggacgggggt ccggctgatg tagggggcgc gacggcagca ccaggcggcg gggccggggg      960

cagccgggag ctggagatgc acactatcag ctccaaggta tttggggaca ttctggactt     1020

cgcctacact tcccgcatcg tggtgcgctt ggagagcttt cccgaactca tgacggccgc     1080

caagttcctg ctgatgaggt cggttatcga gatctgccag gaagtcatca aacagtccaa     1140

cgtacagatc ctggtacccc ctgcccgcgc cgatataatg ctctttcgcc cccctgggac     1200

ctcggacttg ggcttccctt tggacatgac caacggggca gccttggcag ccaacagcaa     1260

tggcatcgcc ggcagcatgc agccagagga ggaggcagct cgggcggctg gtgcagccat     1320

tgcaggccaa gcctctttgc ctgtgttacc tggggtggac cgcttgccca tggtggctgg     1380

acccctatcc ccccaactgc tgacttcccc attccccagt gtggcatcca gtgcccctcc     1440

cctgactggc aagcgaggcc ggggccgccc aaggaaggcc aacctgctgg actcaatgtt     1500

tgggtcccca gggggcctga gggaggcagg catccttcca tgcggtctat gtggtaaggt     1560

gttcactgat gccaaccggc tccggcagca cgaggcccag cacggtgtca ccagcctcca     1620

gctgggctac atcgaccttc ctcctccgag gctgggtgag aatgggctac ccatctctga     1680

agaccccgac ggcccccgaa agaggagccg gaccaggaag caggtggctt gtgagatctg     1740

cggcaagatc ttccgtgatg tgtatcatct taaccggcac aagctgtccc actctgggga     1800

gaagccctac tcctgccctg tgtgtgggtt gcggttcaag agaaaagacc gcatgtccta     1860

ccatgtgcgg tcccatgatg ggtccgtggg caagccttac atctgccaga gctgtgggaa     1920

aggcttctcc aggcctgatc acttgaacgg acatatcaag caggtgcaca cttctgagcg     1980

gcctcacaag tgtcagacct gcaatgcttc ttttgccacc cgagaccgtc tgcgctccca     2040

cctggcctgt catgaagaca aggtgccctg ccaggtgtgt gggaagtact tgcgggcagc     2100

atacatggca gaccacctga agaagcacag cgaggggccc agcaacttct gcagtatctg     2160

taaccgaggt ctccaggcac caggagccca tcctgaatgg gggagcagcg ttccactgcg     2220

ccaggaccta tggcaacaaa gaaggccaga aatgctcaca tcaggatccg attgagagct     2280

ctgactccta tggtgacctc tcagatgcca gcgacctgaa gacgccagag aagcagagtg     2340

ccaatggctc tttctcctgc gacatggcag tccccaaaaa caaaatggag tctgatgggg     2400

agaagaagta cccatgccct gaatgtggga gcttcttccg ctctaagtcc tacttgaaca     2460

aacacatcca gaaggtgcat gtccgggctc tcgggggccc cctgggggac ctgggccctg     2520

cccttggctc acctttctct cctcagcaga acatgtctct cctcgagtcc tttgggtttc     2580

agattgttca gtcggcattt gcgtcatctt tagtagatcc tgaggttgac cagcagccca     2640

tggggcctga agggaaatga ggcagctgct gtgtccccac ggaaacaacc atctggggac     2700

tgctgggaaa tgctgtgaat gcggagggaa gtgatgtttg ggttctgtag ctgagagatt     2760

tttattcatt tttaactgcc ccccaacccc actccaactc cttctccacc acccattctc     2820

ccaatggtct ttagaaatag attttcatct gatattctgc agaaatatca atgagacttg     2880

gtatgggaca ggggcagaaa acactacata ggcctccaag gcaaaaccag tcccagtttc     2940

tttaatggga agaagctgga attcctggtg ctcaattctt agtgacccca atcctatacc     3000

caaatctatg atattctggg acctcagtga ttttggtccc ctcccacttc tctagttcgt     3060

catcctccct tcccatatcc ttcaaaagaa ccacactagg gtctccacct acttatacaa     3120

tgcggatgcc caactgtttt taaggaagcc agaagcatcc catggaccat ggggtgagtg     3180

tcctccaaga gccccctgag ctcagccctc tgcctggagg gctccagacc tttctgagcc     3240

ctgcttggag gcgagcattt tcactgctag gacaagctca gctgttgagg acacccccac     3300

cccaaatttc agttcttacg tgattttaac cattcaacat gctgttgggt tttaattctc     3360

taattattat tattattgtt attatttttt aggaccagtt gtagtgaatt gctactgaaa     3420

gctatcccag gtgatacaga gctctttgta aaccgcagtc acacattagg gttagtatta     3480

aactttgttt agatgtacca taattaactt ggctagttga ttgtttgaag tctatggaag     3540

aaatagtttt atgcaaaatt ttaaaaaatg ccagtctggt cagggaagta gggggtttca     3600

atgctgttgg gaaccaggaa ggtgggacag ccggcaggta gggacattgt gtacctcagt     3660

tgtgtcacat gtgagcaagc ccaggttgac cttgtgatgt gaattgatct gatcagactg     3720

tattaaaaat gttagtacat tactcta                                         3747


<210>  175
<211>  3112
<212>  DNA
<213>  homo sapiens

<400>  175
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtgcct     1560

ttcattatct caagccagat atcgcgtaag tgaactgtcc acttggagct aaaactggcc     1620

ctgtttctgg tcttcgcagc ctagatatga agaatctgct ctgaaaacaa aaaaaaatta     1680

cccttttgtt ggggggggtg gggcagtggt cccaatagga gacaaaggag agtgattgat     1740

tttcttcctc caatagttgg tttcaaatcc ttttgaacac gttcgacaaa agcagtggag     1800

aagaggaaga cctggagcaa taaaagacaa atgcaacatt ttaaggcaat ggtttcacat     1860

ggttacatat caaaacatcc caattcttta gtgctgatca tcgaggagct agaacattcc     1920

atttgcttgt gtgcgtgcgt gcgtgtgtgt gtgtgtgtgt gtattgagat ttacccagac     1980

tggtttgggc aagcagactg ttctaaaata taatagaata ccctaaagta taacatgtcg     2040

atgttcgatg ctgatacttc tacaacttta aaactgctca tttcatgaag caagaatgga     2100

ggaatccttg actcttacac actggaaatt gaaataaaga taaatgcaac catttttagg     2160

aagctagact agctgtaaag gacctcctaa ataaattatt tgttactgta tcctcatttg     2220

taatctagtt gtcaataaat ggcccggaca tgtcttgcta acaggatatg ggctaccagg     2280

aagaaggact tgtttccctt tcctgtgtgg ggagaggtgt gtgacgtttt tccagttcac     2340

atttatttgg tagcccacct gggttggagg aagggcacgg tggagagaaa gtgacatgca     2400

ttcacatatc tgcttatcag tgtgcaatac tgtgtacctc atggatgctt tggcaatgcc     2460

caaggcgata taagcaaaat cagaagtata tttttgcagg tgcttttatt ttcacagccc     2520

ataattcata gtgatagagt gcagtgatgt ttgccatttg ctggacaacc aacacccggg     2580

ttgctccttt gattagagac cagatcagat aattatgctt ttaaactgat tacgtttaca     2640

ttcttctctt ttctatgaaa ggcagggcaa gaacagaagt gttcacatgg ctctcatgta     2700

cttttaaatt atacaatgat atccaatatt aaaagattat aggaactgag gtttacatac     2760

gtttgtgtgg tgacatttta gaatgtcaat aaatttgctt tttgagatgt tgagaggaac     2820

aagaaggtgg aaggcagtgt tatttatttc tttctattct tggaaccacg aatgaggtag     2880

gcacaaatac attcctttta gagttaagaa ctatgacgta gcgagttagt gagactagac     2940

atagtaccga atttagttca tgcattggtc ttagagggtg atggaacaag agaagtacta     3000

tctttgtgtt gcagcctcaa ccaacaacaa tgtgttgtaa aaatgtcttt catgtaaaaa     3060

gtgcagtaaa tatttactat ttataatgaa taaacagtta tgaaaacttg aa             3112


<210>  176
<211>  2941
<212>  DNA
<213>  homo sapiens

<400>  176
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtgcct     1560

ttcattatct caagccagat atcgcttggt ttcaaatcct tttgaacacg ttcgacaaaa     1620

gcagtggaga agaggaagac ctggagcaat aaaagacaaa tgcaacattt taaggcaatg     1680

gtttcacatg gttacatatc aaaacatccc aattctttag tgctgatcat cgaggagcta     1740

gaacattcca tttgcttgtg tgcgtgcgtg cgtgtgtgtg tgtgtgtgtg tattgagatt     1800

tacccagact ggtttgggca agcagactgt tctaaaatat aatagaatac cctaaagtat     1860

aacatgtcga tgttcgatgc tgatacttct acaactttaa aactgctcat ttcatgaagc     1920

aagaatggag gaatccttga ctcttacaca ctggaaattg aaataaagat aaatgcaacc     1980

atttttagga agctagacta gctgtaaagg acctcctaaa taaattattt gttactgtat     2040

cctcatttgt aatctagttg tcaataaatg gcccggacat gtcttgctaa caggatatgg     2100

gctaccagga agaaggactt gtttcccttt cctgtgtggg gagaggtgtg tgacgttttt     2160

ccagttcaca tttatttggt agcccacctg ggttggagga agggcacggt ggagagaaag     2220

tgacatgcat tcacatatct gcttatcagt gtgcaatact gtgtacctca tggatgcttt     2280

ggcaatgccc aaggcgatat aagcaaaatc agaagtatat ttttgcaggt gcttttattt     2340

tcacagccca taattcatag tgatagagtg cagtgatgtt tgccatttgc tggacaacca     2400

acacccgggt tgctcctttg attagagacc agatcagata attatgcttt taaactgatt     2460

acgtttacat tcttctcttt tctatgaaag gcagggcaag aacagaagtg ttcacatggc     2520

tctcatgtac ttttaaatta tacaatgata tccaatatta aaagattata ggaactgagg     2580

tttacatacg tttgtgtggt gacattttag aatgtcaata aatttgcttt ttgagatgtt     2640

gagaggaaca agaaggtgga aggcagtgtt atttatttct ttctattctt ggaaccacga     2700

atgaggtagg cacaaataca ttccttttag agttaagaac tatgacgtag cgagttagtg     2760

agactagaca tagtaccgaa tttagttcat gcattggtct tagagggtga tggaacaaga     2820

gaagtactat ctttgtgttg cagcctcaac caacaacaat gtgttgtaaa aatgtctttc     2880

atgtaaaaag tgcagtaaat atttactatt tataatgaat aaacagttat gaaaacttga     2940

a                                                                     2941


<210>  177
<211>  9150
<212>  DNA
<213>  homo sapiens

<400>  177
ctggcaggaa tttcttgctt ggagctcaga caacaaaggc atagagagat tggttttctt       60

tctctcagca tctccaccca accagcagaa aaccggtctc tgaggttcca ccaaaatatg      120

gaacttgatt ttggacactt tgacgaaaga gataagacat ccaggaacat gcgaggctcc      180

cggatgaatg ggttgcctag ccccactcac agcgcccact gtagcttcta ccgaaccaga      240

accttgcagg cactgagtaa tgagaagaaa gccaagaagg tacgtttcta ccgcaatggg      300

gaccgctact tcaaggggat tgtgtacgct gtgtcctctg accgttttcg cagctttgac      360

gccttgctgg ctgacctgac gcgatctctg tctgacaaca tcaacctgcc tcagggagtg      420

cgttacattt acaccattga tggatccagg aagatcggaa gcatggatga actggaggaa      480

ggggaaagct atgtctgttc ctcagacaac ttctttaaaa aggtggagta caccaagaat      540

gtcaatccca actggtctgt caacgtaaaa acatctgcca atatgaaagc cccccagtcc      600

ttggctagca gcaacagtgc acaggccagg gagaacaagg actttgtgcg ccccaagctg      660

gttaccatca tccgcagtgg ggtgaagcct cggaaggctg tgcgtgtgct tctgaacaag      720

aagacagccc actcttttga gcaagtcctc actgatatca cagaagccat caaactggag      780

accggggttg tcaaaaaact ctacactctg gatggaaaac aggtaacttg tctccatgat      840

ttctttggtg atgatgatgt gtttattgcc tgtggtcctg aaaaatttcg ctatgctcag      900

gatgattttt ctctggatga aaatgaatgc cgagtcatga agggaaaccc atcagccaca      960

gctggcccaa aggcatcccc aacacctcag aagacttcag ccaagagccc tggtcctatg     1020

cgccgaagca agtctccagc tgactcaggt aacgaccaag acgcaaacgg aacctccagc     1080

agccagctct ctacccccaa gtctaagcag tctcccatct ctacgcccac cagtcctggc     1140

agcctccgga agcacaagga cctgtacctg cctctgtcct tggatgactc ggactcgctt     1200

ggtgattcca tgtaaaggag gggagagtgc tcagagtcca gagtacaaat ccaagcctat     1260

cattgtagta gggtacttct gctcaagtgt ccaacagggc tattggtgct ttcaagtttt     1320

tattttgttg ttgttgttat tttgaaaaac acattgtaat atgttgggtt tattttcctg     1380

tgatttctcc tctgggccac tgatccacag ttaccaatta tgagagatag attgataacc     1440

atcctttggg gcagcattcc agggatgcaa aatgtgctag tccatgacct ttcaatggaa     1500

agcttaggtg cctgcgttat atttgccctg tctaattttg cccatacagt cttccttctg     1560

tagagggctg tttacatata cagcacttaa aatgtttgtg tgggaaaaaa aaaactcatt     1620

ggcagatcca agaatgacaa acacaagtgc cccttttctc tggatctcaa gaatggtgga     1680

ggaccctgga aggacagcaa ggcagctccc cagcctcact cttcactcct gattgaggcc     1740

cgggtttgtt gtccagcacc aattctggct gtcaatgggg agaaataaac caacaactta     1800

taattgtgac accagatgct taggatcctg gtgctgggtt agctaagaga atagacagaa     1860

ttggaaaata ctgcagacat ttccgaagag tttataaagc acagtgaatt cctggtcaat     1920

ctctccactg aggcaatttg gaatcaataa gcaattgata atagtttgga gtaagggact     1980

tcatatacct gattcctcta gaaggctgtc taacatacca catgattaca tgaactgtat     2040

ggtatccatc tatctctgtt ctattgaatg ccttgttaac agccaacact gaaaacactg     2100

tgagaatttg ttttcaggtc tgacaccttt cagtctcttt ttatagcaag aaatcaatat     2160

cctttttata aaaattcatg tctgtatttc aggagcaaac tcttcaggct ccttttttat     2220

aaactggtga tttttctttt gtctaaaaaa cacatgaaga aaatttacca aaaaaaaaaa     2280

aaaaagcaga agaataatgt agtttagaaa ttatgctgtc actgccaaac agtaacctcc     2340

aggagaaaac aagatgaata gcagaggcca attcaataga atcagttttt tgatagcttt     2400

ttaacagtta tgcttgcatt aataatttca atgtggacca gacattctaa ttatatttta     2460

aatgaaatgt tacagcatat tttaagcaac tctttttatc tataatccta atatttcata     2520

ctgaagacac agaaatcttt cacttgtctt taacattaga aaggatttct ctttactaag     2580

gactgatcat ttgaaatagt tttcagtctt ttgagataca ggtttataac actgcttttt     2640

tttttctgta atcatagccc ataatggcaa agacaactaa atttaagtga aggtcatgca     2700

tgccaattct gtgtttgctt ttagcagata tgaagatttc cttatttctt tgtaattgtg     2760

cagatatttt gaaaggcaca gcattcgaag ccaagctgct gtttggctac tgaatggctt     2820

gcagttgttc ctccactcta aatggaatga gcttgctgtg tgtgtgtgtg gtggtggtgg     2880

gagggggtgg tgcatgtgtg tgtgtgtgtg tgcatctgca gctgcttcaa aattaggaaa     2940

tactacagga cacccctgta atggattggt ggcaactggg tggcactgct gatgtgcact     3000

gtgtaggggg gaacccagtg gtggtggggt agctcagatg cccctagaca agcttcagat     3060

gtctgtagct accagaaaca ttttcggttc aggaaaagtg agatgatggt agtactggtt     3120

tctggtgaaa ttgaagaacc ccaaatgatg aggatctctt tttgccccct ctcctttttt     3180

tgtagaccca ttcaaaacca ttaataagcc cattttacta agcccctatt tctttctaga     3240

agctcagggt tttcttagtg cctcccagaa cattttgtag ttaattggga aaaagtgata     3300

cttggattag ggggtgtggg cataaagaat ggtgggaggc ctgattttaa acttcaggcc     3360

agaaccccca atgactccac ccatagtctc actttaggtc tcatttagtc catcaccttt     3420

attttaagtt gaggaagtgg aggctggtaa agagcaggac cagaggaaga atccagattt     3480

ccttatgctt gggcctcaca ctagctctct gagtatttcc ttgattgcgg tatatgtact     3540

actagaaaat accaaatgga tatattttct ttaggataac ctttgaacca acaatcttca     3600

ataacaatag tacatcttcc atcttacttt taatcgagta taaggaaatg tttctttatg     3660

gccattttgg agggagcagg ggatgaggct tggcatagtc caaaatttaa gtctccaata     3720

attaattgca ttttaaattg gcccactttc aaggcaattt tttttgtgtg tctgtaactg     3780

agctcctcca cccctgtcat tcacttccaa ttttacccaa tccaatttta gcactcaagt     3840

tccattgtgt taatttctgc acggtcaaca aacatcaagt cagcaagcat ttgccaccac     3900

tccctatact tctccctcct tcttacacac acacacacac acacacacac aatccatctc     3960

ttgcttgttc ctacctcctg atttttcttc cctacagaaa tagaaatagg gacaaagaag     4020

gggaaaatgt atatattggg gctgggctga acaactaact tcataagtag tattaactag     4080

gggtaaattg agagaaaagc tccttttctc ttcactgttt tggaaaggat agccattagc     4140

atgactgctt tgtgtcctta tggactttag tattagccta gattgaatta tagcgttttc     4200

tagctggaag gaaccttaag atcacatcat ctactcctct actccaaatt tctcattctt     4260

caggccagga aaccgagaca cagaggtaaa gtaatttccc caaggtcaca cagctggctg     4320

gggcaggatt gggtttacaa cccacatctc ctggctctta ttccagggcc ttttcccact     4380

aagtagtatt gccttccatt aggctcctga gagttatttc tcagggtcat gttgcatctt     4440

ggagccacat gctgctgccc tgatctcagt gggaaatcca cccagcaacc taatacagcc     4500

ccttttccct gcattcacct ggttcccatc cacatgggtt gcagatgtcc ttgaagagag     4560

tgaggcattg agggccaata ggagcaatgg ggtccctggc cttgtccatc tgattcagga     4620

gatcactgct ccatcgtgag gagccctctg aatagccccc cactgaatgc ttgccttgcc     4680

caaatggaat ggaggaagat tgattttctc catcagttca ccttgtgtca tctcataatg     4740

gttggtcttt ccaggctgag ggaaatgttt cttgtttcca gagtagaaaa agaaagagtg     4800

gaacaatagc tttgttcatc ctaactttct gagatggctt ttcaacattt taaaaaaact     4860

agtgtggcta ccattcactg gcaatgattt cttttagaat atgggagtaa gatgagctag     4920

agaaaataac ctggtctcac tgtggttgcc ctcatccaca atgtccccaa agccatcctg     4980

ctctgatgag gacaatttcc aggtataagc aaggggcttt gtgacaaaaa tgtaccctgg     5040

ctgatgttaa acattggctc ctgtgtttgc accaaaatag caagctgtgt gctctataca     5100

ctcttcccat cgtcttgtgt acactgctcc tgtggccttc cacagcagaa accagggcaa     5160

aagggtccaa acacatggtt ttccttgctg caaggctctt cctgggaact aagggggtat     5220

ttattagttc agttctaaga gacctccttc tgggcttacc ccactcctca ggtacttctc     5280

tctccttcct ccttctcctc cacagtcaca agtaaccaag gaacctgaaa gtggatgtgt     5340

agctatttga agaaggcaag gaaccctgag attcttcttt gaatcctcta gtccaagtct     5400

tagaccagtg attggtgctt accttgaaca aaattttgtc tgtgttccta atcccttcaa     5460

tactctgggt acaatgctcc caatcaccct gcacatttga ttctaaatgg cttttatttt     5520

ttaaaaatcc atatccctag gacaagagaa caggatgcct atatccccaa aatgagctcc     5580

aggacactga tgggaatgat cccaaagatc accccacctc agaaacgtct gtgccaagag     5640

acttccccag atagaaacac tgggacagtg gtttgaacga cttcttttat ggttgtccag     5700

tttgctatgg aaataaaagg cattgatttt ttaaaaagat gattggaacc tgtctttggc     5760

cacatagggc cacttggatc catttccagg ccttactcat atattgcctt cactgaaggg     5820

ctttggcttt aagtcccaga ctggtctccc aagtgaacca taagtgtttt ggagctcatc     5880

tggggtgagg catgagaatg ttgccccatc tatcccttca ggaaaaggtg ccttccctcc     5940

ctttctccta aagcctggtc cccagaaatt gtttttgtct ccaaaagtct agtatggtct     6000

ttatacaccc agactcttag tgttgcgtcc tgccttgttt ccttgttaag gatctatgca     6060

gacctcccgc tttggcttag ctagcgtgac attggctatc atttgacaag actaactttt     6120

tttttttttt ttttttgact gagtctccct ctgtcaccta ggctggagtg cagtggcaca     6180

atcttggctc gctgcaacct tcacccttca cctcccaggt cgaagcgatt ctcctgcctc     6240

agtctcccga gtagctggga ttacaggcgt gcgccaccaa atctggctat ttttttatta     6300

ttattatttt tagtagagat ggggtttcac catgttggcc agactggtct tgaactcttg     6360

gcctcaaatt atctgcccac ctcggcctcc caaagtgctg ggattacagg catgagccac     6420

catgcccagc tgacaagact aattttttat cccttggttt attggcttca acatcttctg     6480

gaatcagagg tgattttttc ttaccttgga tgcctgagac taggggagta tagaattcca     6540

attggtaatt aaggcatctt tctgctcctg atcagaaggg caggttagtt gggagaggtc     6600

agatggcaca acagaagtca ccttgtaagt aaggcaaaga cttgaaggca ttagcgtttc     6660

tcattactag gtcaataacc tgagggaatc aatggctttt tgccgctcta cctcttgtgt     6720

atctctttga cttttctttc tctgtctagt ttcctctgtt ctcagtttat attctatgtt     6780

atcagtctct ctttccacag tacaaacatc catcctttct cctgtgcaat tctgtctctc     6840

cctcttatta tctttatttg tactttttcc ttcctccctg tctaggcatt gggcatgtgc     6900

ctcttcttag cctgtgattt tgccttggga ctgatgataa attatttcca gattcaatca     6960

gccctggtcc taccccagtc caatcagaag tatgttggtg ggaatcaacc tgatcctggc     7020

cctttcttct tctccatttt cattcgtaat ccccctcagc agatctttac aagcagtttc     7080

cttatagctc atgtatcttt aggtctttgc cttccaagca ctgtacagaa tactttgtgg     7140

ttccttttta gtctgacatt ttgtggagca gtgaagcgtg ctcagagaca taatcagctg     7200

aagagaaaaa atccacccat ggatttatat cagctaaata ctaataattg attttgtttg     7260

atgtgcccat aatttttaaa gctgcaatat aatataatga gggaccacag gtaatttctc     7320

ctgtcatttg ttttggctgg atgggggtgg gggagtaatt gcttaaagtt ttaccattac     7380

acattaaact ctctataata atcttgtttg gggcttgcta actgttgagc tgttttaact     7440

aaactggtag gcaatcggag ttgatttaaa tgaaaagata atttaacaaa tctatactat     7500

aaaaagagac atttgcttaa ttgacatgta ttttttcctt ctgagtcacc taaacattta     7560

ctcttgacac caactgttca tgatactgaa tagacagtcc atataagaga aattagtgga     7620

cctaaagaag ccagattgta ggtgttaatt tattaaacag agtgcaaagc ccttggaaat     7680

gtcactgctt ggcaatacca tatggaatgc caaaatttac aatgactttt ctttataagt     7740

tatccaaaag ggatttgaac aagtaagagg ttatgccaaa atgtctccaa tgtatggtcc     7800

tgtaatatat tgcagcttga agccaatgat cccttatgac ttgtatacaa ctaatgcatg     7860

ttttattgaa ttttgcattt cccacgtgtg gtaagttctt taaaatgttt ttgatcacct     7920

ttttgtgcca ttaaacttgt acagaaaatg tttttatggc cattttcaaa gggagaaagt     7980

ttaaaatgga aacagcccac cctttctgcc ctatagctgt agttagaatt gagtacctgt     8040

agcaaaacag ctgtaattgg tggttgtagt gttagaggtg ttagcttgct agtgactagc     8100

tttggagagt aaatgcatgg tattgtacat cacatttctt aactcgtttt aacctctgaa     8160

aagaatatat tcttctttgt agtccttctt cccaccccct tgccctctcc ctctccctgc     8220

tcccagttgt cttacagttg taaatatctg atttgaggcc caataactct tgccaagtaa     8280

agtcagcaaa caacaaacaa accaaaatgt ggggaaaagg catttctcaa ccatctctca     8340

gcagttattg atcatttctt aaggaacagc attgtgatca aagactcaac tttacgtaaa     8400

aatcagtggt aaattggggt tgtatttggc catttgatta catttcagga ttgaatagtt     8460

ttcagaatca catgtaatcc aaagacagta ggtagtgatg tcccttatcc ctgcagctgt     8520

tttaagatag agacctcaga agactctgct tgaccgatga ccaataatta tttgaaaaaa     8580

aaagaaaaaa tgagagaaat aaaacagata tttaagaact ttagccacct atttagaata     8640

gttatagcca gaaaaaaaaa caagggcatg agttcaaatg cattactatc agtgtcctag     8700

gcaataccta acctactctg aaattgtgat tcaaaagcag tatttcaaga ggcattctcc     8760

ttttttggtt tgctgacccc acttggactg gtaggtttgg tgaggccccc ataaaccagc     8820

tggagcagac ccttttcatc tcctgtgcct gtaacacccc tcttccccca ccccctccgc     8880

aattcaatga gggctttctt gggtcagagg acttcaaggt tgtctagaga agtttgccat     8940

gtgtgtaagg tgctgtgaac tgtgagtgct gaagattcgc agcattcaat accaggcagc     9000

caaagagctg ctcttgcaat tattttggct ctcaagctct gttcttcatc gcattctcat     9060

ttctgtgtac atttgcaaga tgtgtgtaat gtcattttcc aaaaataaaa tttgatttca     9120

ataaaaaaaa aaaaaaaaaa aaaaaaaaaa                                      9150


<210>  178
<211>  9135
<212>  DNA
<213>  homo sapiens

<400>  178
ctggcaggaa tttcttgctt ggagctcaga caacaaaggc atagagagat tggttttctt       60

tctctcagca tctccaccca accagcagaa aaccggtctc tgaggttcca ccaaaatatg      120

gaacttgatt ttggacactt tgacgaaaga gataagacat ccaggaacat gcgaggctcc      180

cggatgaatg ggttgcctag ccccactcac agcgcccact gtagcttcta ccgaaccaga      240

accttgcagg cactgagtaa tgagaagaaa gccaagaagg tacgtttcta ccgcaatggg      300

gaccgctact tcaaggggat tgtgtacgct gtgtcctctg accgttttcg cagctttgac      360

gccttgctgg ctgacctgac gcgatctctg tctgacaaca tcaacctgcc tcagggagtg      420

cgttacattt acaccattga tggatccagg aagatcggaa gcatggatga actggaggaa      480

ggggaaagct atgtctgttc ctcagacaac ttctttaaaa aggtggagta caccaagaat      540

gtcaatccca actggtctgt caacgtaaaa acatctgcca atatgaaagc cccccagtcc      600

ttggctagca gcaacagtgc acaggccagg gagaacaagg actttgtgcg ccccaagctg      660

gttaccatca tccgcagtgg ggtgaagcct cggaaggctg tgcgtgtgct tctgaacaag      720

aagacagccc actcttttga gcaagtcctc actgatatca cagaagccat caaactggag      780

accggggttg tcaaaaaact ctacactctg gatggaaaac aggtaacttg tctccatgat      840

ttctttggtg atgatgatgt gtttattgcc tgtggtcctg aaaaatttcg ctatgctcag      900

gatgattttt ctctggatga aaatgaatgc cgagtcatga agggaaaccc atcagccaca      960

gctggcccaa aggcatcccc aacacctcag aagacttcag ccaagagccc tggtcctatg     1020

cgccgaagca agtctccagc tgactcagca aacggaacct ccagcagcca gctctctacc     1080

cccaagtcta agcagtctcc catctctacg cccaccagtc ctggcagcct ccggaagcac     1140

aaggacctgt acctgcctct gtccttggat gactcggact cgcttggtga ttccatgtaa     1200

aggaggggag agtgctcaga gtccagagta caaatccaag cctatcattg tagtagggta     1260

cttctgctca agtgtccaac agggctattg gtgctttcaa gtttttattt tgttgttgtt     1320

gttattttga aaaacacatt gtaatatgtt gggtttattt tcctgtgatt tctcctctgg     1380

gccactgatc cacagttacc aattatgaga gatagattga taaccatcct ttggggcagc     1440

attccaggga tgcaaaatgt gctagtccat gacctttcaa tggaaagctt aggtgcctgc     1500

gttatatttg ccctgtctaa ttttgcccat acagtcttcc ttctgtagag ggctgtttac     1560

atatacagca cttaaaatgt ttgtgtggga aaaaaaaaac tcattggcag atccaagaat     1620

gacaaacaca agtgcccctt ttctctggat ctcaagaatg gtggaggacc ctggaaggac     1680

agcaaggcag ctccccagcc tcactcttca ctcctgattg aggcccgggt ttgttgtcca     1740

gcaccaattc tggctgtcaa tggggagaaa taaaccaaca acttataatt gtgacaccag     1800

atgcttagga tcctggtgct gggttagcta agagaataga cagaattgga aaatactgca     1860

gacatttccg aagagtttat aaagcacagt gaattcctgg tcaatctctc cactgaggca     1920

atttggaatc aataagcaat tgataatagt ttggagtaag ggacttcata tacctgattc     1980

ctctagaagg ctgtctaaca taccacatga ttacatgaac tgtatggtat ccatctatct     2040

ctgttctatt gaatgccttg ttaacagcca acactgaaaa cactgtgaga atttgttttc     2100

aggtctgaca cctttcagtc tctttttata gcaagaaatc aatatccttt ttataaaaat     2160

tcatgtctgt atttcaggag caaactcttc aggctccttt tttataaact ggtgattttt     2220

cttttgtcta aaaaacacat gaagaaaatt taccaaaaaa aaaaaaaaaa gcagaagaat     2280

aatgtagttt agaaattatg ctgtcactgc caaacagtaa cctccaggag aaaacaagat     2340

gaatagcaga ggccaattca atagaatcag ttttttgata gctttttaac agttatgctt     2400

gcattaataa tttcaatgtg gaccagacat tctaattata ttttaaatga aatgttacag     2460

catattttaa gcaactcttt ttatctataa tcctaatatt tcatactgaa gacacagaaa     2520

tctttcactt gtctttaaca ttagaaagga tttctcttta ctaaggactg atcatttgaa     2580

atagttttca gtcttttgag atacaggttt ataacactgc tttttttttt ctgtaatcat     2640

agcccataat ggcaaagaca actaaattta agtgaaggtc atgcatgcca attctgtgtt     2700

tgcttttagc agatatgaag atttccttat ttctttgtaa ttgtgcagat attttgaaag     2760

gcacagcatt cgaagccaag ctgctgtttg gctactgaat ggcttgcagt tgttcctcca     2820

ctctaaatgg aatgagcttg ctgtgtgtgt gtgtggtggt ggtgggaggg ggtggtgcat     2880

gtgtgtgtgt gtgtgtgcat ctgcagctgc ttcaaaatta ggaaatacta caggacaccc     2940

ctgtaatgga ttggtggcaa ctgggtggca ctgctgatgt gcactgtgta ggggggaacc     3000

cagtggtggt ggggtagctc agatgcccct agacaagctt cagatgtctg tagctaccag     3060

aaacattttc ggttcaggaa aagtgagatg atggtagtac tggtttctgg tgaaattgaa     3120

gaaccccaaa tgatgaggat ctctttttgc cccctctcct ttttttgtag acccattcaa     3180

aaccattaat aagcccattt tactaagccc ctatttcttt ctagaagctc agggttttct     3240

tagtgcctcc cagaacattt tgtagttaat tgggaaaaag tgatacttgg attagggggt     3300

gtgggcataa agaatggtgg gaggcctgat tttaaacttc aggccagaac ccccaatgac     3360

tccacccata gtctcacttt aggtctcatt tagtccatca cctttatttt aagttgagga     3420

agtggaggct ggtaaagagc aggaccagag gaagaatcca gatttcctta tgcttgggcc     3480

tcacactagc tctctgagta tttccttgat tgcggtatat gtactactag aaaataccaa     3540

atggatatat tttctttagg ataacctttg aaccaacaat cttcaataac aatagtacat     3600

cttccatctt acttttaatc gagtataagg aaatgtttct ttatggccat tttggaggga     3660

gcaggggatg aggcttggca tagtccaaaa tttaagtctc caataattaa ttgcatttta     3720

aattggccca ctttcaaggc aatttttttt gtgtgtctgt aactgagctc ctccacccct     3780

gtcattcact tccaatttta cccaatccaa ttttagcact caagttccat tgtgttaatt     3840

tctgcacggt caacaaacat caagtcagca agcatttgcc accactccct atacttctcc     3900

ctccttctta cacacacaca cacacacaca cacacaatcc atctcttgct tgttcctacc     3960

tcctgatttt tcttccctac agaaatagaa atagggacaa agaaggggaa aatgtatata     4020

ttggggctgg gctgaacaac taacttcata agtagtatta actaggggta aattgagaga     4080

aaagctcctt ttctcttcac tgttttggaa aggatagcca ttagcatgac tgctttgtgt     4140

ccttatggac tttagtatta gcctagattg aattatagcg ttttctagct ggaaggaacc     4200

ttaagatcac atcatctact cctctactcc aaatttctca ttcttcaggc caggaaaccg     4260

agacacagag gtaaagtaat ttccccaagg tcacacagct ggctggggca ggattgggtt     4320

tacaacccac atctcctggc tcttattcca gggccttttc ccactaagta gtattgcctt     4380

ccattaggct cctgagagtt atttctcagg gtcatgttgc atcttggagc cacatgctgc     4440

tgccctgatc tcagtgggaa atccacccag caacctaata cagccccttt tccctgcatt     4500

cacctggttc ccatccacat gggttgcaga tgtccttgaa gagagtgagg cattgagggc     4560

caataggagc aatggggtcc ctggccttgt ccatctgatt caggagatca ctgctccatc     4620

gtgaggagcc ctctgaatag ccccccactg aatgcttgcc ttgcccaaat ggaatggagg     4680

aagattgatt ttctccatca gttcaccttg tgtcatctca taatggttgg tctttccagg     4740

ctgagggaaa tgtttcttgt ttccagagta gaaaaagaaa gagtggaaca atagctttgt     4800

tcatcctaac tttctgagat ggcttttcaa cattttaaaa aaactagtgt ggctaccatt     4860

cactggcaat gatttctttt agaatatggg agtaagatga gctagagaaa ataacctggt     4920

ctcactgtgg ttgccctcat ccacaatgtc cccaaagcca tcctgctctg atgaggacaa     4980

tttccaggta taagcaaggg gctttgtgac aaaaatgtac cctggctgat gttaaacatt     5040

ggctcctgtg tttgcaccaa aatagcaagc tgtgtgctct atacactctt cccatcgtct     5100

tgtgtacact gctcctgtgg ccttccacag cagaaaccag ggcaaaaggg tccaaacaca     5160

tggttttcct tgctgcaagg ctcttcctgg gaactaaggg ggtatttatt agttcagttc     5220

taagagacct ccttctgggc ttaccccact cctcaggtac ttctctctcc ttcctccttc     5280

tcctccacag tcacaagtaa ccaaggaacc tgaaagtgga tgtgtagcta tttgaagaag     5340

gcaaggaacc ctgagattct tctttgaatc ctctagtcca agtcttagac cagtgattgg     5400

tgcttacctt gaacaaaatt ttgtctgtgt tcctaatccc ttcaatactc tgggtacaat     5460

gctcccaatc accctgcaca tttgattcta aatggctttt attttttaaa aatccatatc     5520

cctaggacaa gagaacagga tgcctatatc cccaaaatga gctccaggac actgatggga     5580

atgatcccaa agatcacccc acctcagaaa cgtctgtgcc aagagacttc cccagataga     5640

aacactggga cagtggtttg aacgacttct tttatggttg tccagtttgc tatggaaata     5700

aaaggcattg attttttaaa aagatgattg gaacctgtct ttggccacat agggccactt     5760

ggatccattt ccaggcctta ctcatatatt gccttcactg aagggctttg gctttaagtc     5820

ccagactggt ctcccaagtg aaccataagt gttttggagc tcatctgggg tgaggcatga     5880

gaatgttgcc ccatctatcc cttcaggaaa aggtgccttc cctccctttc tcctaaagcc     5940

tggtccccag aaattgtttt tgtctccaaa agtctagtat ggtctttata cacccagact     6000

cttagtgttg cgtcctgcct tgtttccttg ttaaggatct atgcagacct cccgctttgg     6060

cttagctagc gtgacattgg ctatcatttg acaagactaa cttttttttt tttttttttt     6120

tgactgagtc tccctctgtc acctaggctg gagtgcagtg gcacaatctt ggctcgctgc     6180

aaccttcacc cttcacctcc caggtcgaag cgattctcct gcctcagtct cccgagtagc     6240

tgggattaca ggcgtgcgcc accaaatctg gctatttttt tattattatt atttttagta     6300

gagatggggt ttcaccatgt tggccagact ggtcttgaac tcttggcctc aaattatctg     6360

cccacctcgg cctcccaaag tgctgggatt acaggcatga gccaccatgc ccagctgaca     6420

agactaattt tttatccctt ggtttattgg cttcaacatc ttctggaatc agaggtgatt     6480

ttttcttacc ttggatgcct gagactaggg gagtatagaa ttccaattgg taattaaggc     6540

atctttctgc tcctgatcag aagggcaggt tagttgggag aggtcagatg gcacaacaga     6600

agtcaccttg taagtaaggc aaagacttga aggcattagc gtttctcatt actaggtcaa     6660

taacctgagg gaatcaatgg ctttttgccg ctctacctct tgtgtatctc tttgactttt     6720

ctttctctgt ctagtttcct ctgttctcag tttatattct atgttatcag tctctctttc     6780

cacagtacaa acatccatcc tttctcctgt gcaattctgt ctctccctct tattatcttt     6840

atttgtactt tttccttcct ccctgtctag gcattgggca tgtgcctctt cttagcctgt     6900

gattttgcct tgggactgat gataaattat ttccagattc aatcagccct ggtcctaccc     6960

cagtccaatc agaagtatgt tggtgggaat caacctgatc ctggcccttt cttcttctcc     7020

attttcattc gtaatccccc tcagcagatc tttacaagca gtttccttat agctcatgta     7080

tctttaggtc tttgccttcc aagcactgta cagaatactt tgtggttcct ttttagtctg     7140

acattttgtg gagcagtgaa gcgtgctcag agacataatc agctgaagag aaaaaatcca     7200

cccatggatt tatatcagct aaatactaat aattgatttt gtttgatgtg cccataattt     7260

ttaaagctgc aatataatat aatgagggac cacaggtaat ttctcctgtc atttgttttg     7320

gctggatggg ggtgggggag taattgctta aagttttacc attacacatt aaactctcta     7380

taataatctt gtttggggct tgctaactgt tgagctgttt taactaaact ggtaggcaat     7440

cggagttgat ttaaatgaaa agataattta acaaatctat actataaaaa gagacatttg     7500

cttaattgac atgtattttt tccttctgag tcacctaaac atttactctt gacaccaact     7560

gttcatgata ctgaatagac agtccatata agagaaatta gtggacctaa agaagccaga     7620

ttgtaggtgt taatttatta aacagagtgc aaagcccttg gaaatgtcac tgcttggcaa     7680

taccatatgg aatgccaaaa tttacaatga cttttcttta taagttatcc aaaagggatt     7740

tgaacaagta agaggttatg ccaaaatgtc tccaatgtat ggtcctgtaa tatattgcag     7800

cttgaagcca atgatccctt atgacttgta tacaactaat gcatgtttta ttgaattttg     7860

catttcccac gtgtggtaag ttctttaaaa tgtttttgat cacctttttg tgccattaaa     7920

cttgtacaga aaatgttttt atggccattt tcaaagggag aaagtttaaa atggaaacag     7980

cccacccttt ctgccctata gctgtagtta gaattgagta cctgtagcaa aacagctgta     8040

attggtggtt gtagtgttag aggtgttagc ttgctagtga ctagctttgg agagtaaatg     8100

catggtattg tacatcacat ttcttaactc gttttaacct ctgaaaagaa tatattcttc     8160

tttgtagtcc ttcttcccac ccccttgccc tctccctctc cctgctccca gttgtcttac     8220

agttgtaaat atctgatttg aggcccaata actcttgcca agtaaagtca gcaaacaaca     8280

aacaaaccaa aatgtgggga aaaggcattt ctcaaccatc tctcagcagt tattgatcat     8340

ttcttaagga acagcattgt gatcaaagac tcaactttac gtaaaaatca gtggtaaatt     8400

ggggttgtat ttggccattt gattacattt caggattgaa tagttttcag aatcacatgt     8460

aatccaaaga cagtaggtag tgatgtccct tatccctgca gctgttttaa gatagagacc     8520

tcagaagact ctgcttgacc gatgaccaat aattatttga aaaaaaaaga aaaaatgaga     8580

gaaataaaac agatatttaa gaactttagc cacctattta gaatagttat agccagaaaa     8640

aaaaacaagg gcatgagttc aaatgcatta ctatcagtgt cctaggcaat acctaaccta     8700

ctctgaaatt gtgattcaaa agcagtattt caagaggcat tctccttttt tggtttgctg     8760

accccacttg gactggtagg tttggtgagg cccccataaa ccagctggag cagacccttt     8820

tcatctcctg tgcctgtaac acccctcttc ccccaccccc tccgcaattc aatgagggct     8880

ttcttgggtc agaggacttc aaggttgtct agagaagttt gccatgtgtg taaggtgctg     8940

tgaactgtga gtgctgaaga ttcgcagcat tcaataccag gcagccaaag agctgctctt     9000

gcaattattt tggctctcaa gctctgttct tcatcgcatt ctcatttctg tgtacatttg     9060

caagatgtgt gtaatgtcat tttccaaaaa taaaatttga tttcaataaa aaaaaaaaaa     9120

aaaaaaaaaa aaaaa                                                      9135


<210>  179
<211>  907
<212>  DNA
<213>  homo sapiens

<400>  179
cttttcttaa gggaaaaatc actctgtgtt cttttaaaat ccctcaggtt ttatgtttta       60

ttgctaccag agtctgcctc cctgaggttc ttgtatagac tagttatttc cctctgtaaa      120

gaagctgttc tattcgttct cgcctggttt ggaacaaact gaacacttcc aaaggaggca      180

gtccttgcag ccttgtctcc ttccactccc ctcctcccca cagtcctggc tggagcagcg      240

agtctgtcga tcccaggcca gagacaaggc agacaaaggt tcatttgtaa agaagctcct      300

tccagcacct cctctcttct ccttttgccc aaactcaccc agtgagtgtg agcatttaag      360

aagcatcctc tgccaagacc aaaaggaaag aagaaaaagg gccaaaagcc aaaatgaaac      420

tgatggtact tgttttcacc attgggctaa ctttgctgct aggagttcaa gccatgcctg      480

caaatcgcct ctcttgctac agaaagatac taaaagatca caactgtcac aaccttccgg      540

aaggagtagc tgacctgaca cagattgatg tcaatgtcca ggatcatttc tgggatggga      600

agggatgtga gatgatctgt tactgcaact tcagcgaatt gctctgctgc ccaaaagacg      660

ttttctttgg accaaagatc tctttcgtga ttccttgcaa caatcaatga gaatcttcat      720

gtattctgga gaacaccatt cctgatttcc cacaaactgc actacatcag tataactgca      780

tttctagttt ctatatagtg caatagagca tagattctat aaattcttac ttgtctaaga      840

caagtaaatc tgtgttaaac aagtagtaat aaaagttaat tcaatctaat ttttctctgt      900

ggaaaaa                                                                907


<210>  180
<211>  5260
<212>  DNA
<213>  homo sapiens

<400>  180
agtctttgtg cagtcagggc ttctgctggg cagggccggc tgttaatctc gcctggcgga       60

gcggacaccg gggcgtggtg ggggagatgg gccttatagg tggcgtccgc tggtgagaaa      120

caccttgcgc aggtaaaagg gtggcggcga gagggagttc ccacccgtgg ctttcttaga      180

gaaatgaagt cttaagtctt aaatagacaa caaggagggg ccgatcggtg tcttttggac      240

gcgtctggag cccctccctc cgccaaagga aaagcccctt ggatgagagg caggcgcttc      300

agagaagcta agaaaagcac ctctccgcgc gccccacctc ctccgcctcg cgctcctcct      360

gagcagcggg cccagactgc gctccggccg cggccctcgc cccgcggagc cctcctaccc      420

cggcccgacg ctcggcccgc gacctgcccc gagccctctc catggaggca gcccgcccct      480

ccggctcctg gaacggagcc ctctgccggc tgctcctgct gaccctcgcg atcttaatat      540

ttgccagtga tgcctgcaaa aatgtgacat tacatgttcc ctccaaacta gatgccgaga      600

aacttgttgg tagagttaac ctgaaagagt gctttacagc tgcaaatcta attcattcaa      660

gtgatcctga cttccaaatt ttggaggatg gttcagtcta tacaacaaat actattctat      720

tgtcctcgga gaagagaagt tttaccatat tactttccaa cactgagaac caagaaaaga      780

agaaaatatt tgtctttttg gagcatcaaa caaaggtcct aaagaaaaga catactaaag      840

aaaaagttct aaggcgcgcc aagagaagat gggctccaat tccttgttcg atgctagaaa      900

actccttggg tccttttcca cttttccttc aacaggttca atctgacacg gcccaaaact      960

ataccatata ctattccata agaggtcctg gagttgacca agaacctcgg aatttatttt     1020

atgtggagag agacactgga aacttgtatt gtactcgtcc tgtagatcgt gagcagtatg     1080

aatcttttga gataattgcc tttgcaacaa ctccagatgg gtatactcca gaacttccac     1140

tgcccctaat aatcaaaata gaggatgaaa atgataacta cccaattttt acagaagaaa     1200

cttatacttt tacaattttt gaaaattgca gagtgggcac tactgtggga caagtgtgtg     1260

ctactgacaa agatgagcct gacacgatgc acacacgcct gaagtactcc atcattgggc     1320

aggtgccacc atcacccacc ctattttcta tgcatccaac tacaggcgtg atcaccacaa     1380

catcatctca gctagacaga gagttaattg acaagtacca gttgaaaata aaagtacaag     1440

acatggatgg tcagtatttt ggtctacaga caacttcaac ttgtatcatt aacattgatg     1500

atgtaaatga ccacttgcca acatttactc gtacttctta tgtgacatca gtggaagaaa     1560

atacagttga tgtggaaatc ttacgagtta ctgttgagga taaggactta gtgaatactg     1620

ctaactggag agctaattat accattttaa agggcaatga aaatggcaat tttaaaattg     1680

taacagatgc caaaaccaat gaaggagttc tttgtgtagt taagcctttg aattatgaag     1740

aaaagcaaca gatgatcttg caaattggtg tagttaatga agctccattt tccagagagg     1800

ctagtccaag atcagccatg agcacagcaa cagttactgt taatgtagaa gatcaggatg     1860

agggccctga gtgtaaccct ccaatacaga ctgttcgcat gaaagaaaat gcagaagtgg     1920

gaacaacaag caatggatat aaagcatatg acccagaaac aagaagtagc agtggcataa     1980

ggtataagaa attaactgat ccaacagggt gggtcaccat tgatgaaaat acaggatcaa     2040

tcaaagtttt cagaagcctg gatagagagg cagagaccat caaaaatggc atatataata     2100

ttacagtcct tgcatcagac caaggaggga gaacatgtac ggggacactg ggcattatac     2160

ttcaagacgt gaatgataac agcccattca tacctaaaaa gacagtgatc atctgcaaac     2220

ccaccatgtc atctgcggag attgttgcgg ttgatcctga tgagcctatc catggcccac     2280

cctttgactt tagtctggag agttctactt cagaagtaca gagaatgtgg agactgaaag     2340

caattaatga tacagcagca cgtctttcct atcagaatga tcctccattt ggctcatatg     2400

tagtacctat aacagtgaga gatagacttg gcatgtctag tgtcacttca ttggatgtta     2460

cactgtgtga ctgcattacc gaaaatgact gcacacatcg tgtagatcca aggattggcg     2520

gtggaggagt acaacttgga aagtgggcca tccttgcaat attgttgggc atagcattgc     2580

tcttttgcat cctgtttacg ctggtctgtg gggcttctgg gacgtctaaa caaccaaaag     2640

taattcctga tgatttagcc cagcagaacc taattgtatc aaacacagaa gctcctggag     2700

atgacaaagt gtattctgcg aatggcttca caacccaaac tgtgggcgct tctgctcagg     2760

gagtttgtgg caccgtggga tcaggaatca aaaacggagg tcaggagacc atcgaaatgg     2820

tgaaaggagg acaccagacc tcggaatcct gccggggggc tggccaccat cacaccctgg     2880

actcctgcag gggaggacac acggaggtgg acaactgcag atacacttac tcggagtggc     2940

acagttttac tcagccccgt cttggtgaag aatccattag aggacacact ctgattaaaa     3000

attaaacaat gaaagaaagt gtatctgtgt aatcaagatg aaaatcacaa gcatgcccaa     3060

gactatgtcc tgacatataa ctatgaagga agaggatcgg tggctgggtc tgtaggttgt     3120

tgcagtgaac gacaagaaga agatgggctt gaatttttgg ataatttgga gcccaaattt     3180

aggacactag cagaagcatg catgaagaga tgagtgtgtt ctaataagtc tctgaaagcc     3240

agtggcttta tgacttttaa aaaaaattac aaaccaagaa ttttttaaag cagaagatgc     3300

tatttgtggg ggtttttctc tcattatttg gatggaatct ctttggtcaa atgcacattt     3360

acagagagac actataaaca agtacacaaa tttttcaatt tttacatatt tttaaattac     3420

ttatcttcta tccaaggagg tctacagaga aattaaagtc tgccttattt gttacatttg     3480

ggtataatga caacagccaa tttatagtgc aataaaatgt aattaattca agtccttatt     3540

atagactatt tgaagcacaa cctaatggaa aattgtagag accttgcttt aacattatct     3600

ccagttaatt aagtgttcat gtggtgcttg gaaactgttg ttttcctgaa catctaaagt     3660

gtgtagactg cattcttgct attattttat tcttgtaatg tgaccttttc actgtgcaaa     3720

gggagatttc tagccaggca ttgactatta caatttcatt ttggtggagt ttagttttag     3780

gttttattgt atataaaatc ctgcactgaa tctgtgtctc ctctgttacc tacttttgcc     3840

agtgaaattt aagttttaaa atactttcag aatgtatttt tactactgca agtttttggt     3900

ctttaaaatg tcaagtagca tctctctctt tctctctgtc tctttctgtt tctctctcca     3960

gttttttttt tttttttaat ttccatatgg gctaaagaat ccaaatattt taaaaatctg     4020

tctctctttt cttctctcat aaagtgaatt attccttttt tttgttttat gtaagtgtat     4080

atattcttag tttttcttga aatcattgta atgttaactt tgttgtttca aatatcttgg     4140

tgattgcttc attatctctt caacaaaaaa aacctttaat tttgccattg aaactgtaga     4200

actatgccat gcttttatta gaagcagtgc tctgtgttaa caacaagaat ggtgtaatta     4260

gaattgggat gtggatattt actgtatgac aacacattta cagttctgta atgcaaggat     4320

gcagtttaaa aatgtgaagt agtgatggtt tttgaaataa gctttaaaat atagggatct     4380

tgaaggctcc ctggggtaac tattttataa cttagataaa atggctagtc atatctgtgt     4440

gtttgtaaag ttattttttt aatattttaa gattacaatt ttaacaaatg tagaaatgag     4500

ccaaactatt taaattttaa aacagtaaaa caaaatgaaa cttaatagct cacaaaattc     4560

cagtccatgt ttcatgactt attttagtca atgaattttc tatttatact aaacatatgg     4620

acattttaaa tgtgtttcta atatttttga ttatctataa tgtgcctgtc ttcaattcac     4680

aagattgggt tataacaatt atttgccaga ttaacactag ggaattattt gataaccagc     4740

ttatcttatc agtagtttta ttgctgatca ggcaaaaata gttttccaaa gttattttta     4800

ataaagtata tacaaaattc ttatatatta ctagtcatga taaagtaaat taagcagttt     4860

ttaaaactta gtgtgagttt gttcatcaca ggtctgatat gagtttaagg gatttcgcac     4920

tccctgaatc agagaagtaa gaccccttcc ttagattcct gttatacatt ttttaaaatg     4980

tagagtttgt tttggagaca ttttcagtgc attgttattg ccatatttat ataatatgac     5040

tattctaaag gctgtgaggc catggggtat tggttaagtt gcttgctttt gctttgtcca     5100

ttttcatcat tttaaaatgg gggataataa cagaacttgt ttcctagggc cattgtaagt     5160

cacttgaata aaaaatagtt ttgaagcatg agagtcatac agagcggtcc acctaaaagg     5220

cactcctgat aataataaat gattttaaac aagtaaaaaa                           5260


<210>  181
<211>  2824
<212>  DNA
<213>  homo sapiens

<400>  181
gaactttttt aaaaattaaa tttttatttt gagatcactg tttgtgttca gttgtaagaa       60

acaagagaga ttctgtgtac cctttaccca ttcctccatg ttgcaaaact agcacaatat      120

caccgccacg gtagacgcag tgaggccata agacatttcc gtcagcaaaa gggtcacttc      180

ttgtgcccct ttagaaccac acccacccct gccttccaac tattaatgct ggcaggactt      240

agccagaccg caagggcgcc tactccgaac aaggaagagg gtcaggcgct gggagggcga      300

ctgcaagcgg acaggcagca cctgcgacca cggtacttgg ggacaccaca aaagtccgca      360

gagcaggcac cgcggcactt ccgcgagcgc cgcaggccct gcccctttcg ccgtcgccga      420

ccaattgccg cccgaagacc gaaccgcttc agcggagggc cggaagtgag ccgcagcttt      480

tcctttctgc caccgccttg tccaagatgg cggacctcca ccgccagctg caggagtacc      540

tggcgcaggg gaaagctggc ggcccggcgg ccgcggagcc gctgctcgcc gcggagaagg      600

cggaggagcc cggggaccgg ccggcggagg agtggctggg ccgcgcgggc ttgcgctgga      660

cgtgggcgcg gagccctgcg gagtcggcag cggccggcct gacgtgcctc ccgagcgtga      720

cgcgcgggca gcggctggcg gcgggcggcg ggtgcctgct gctggctgca ctgtgtttcg      780

gcctagccgc gctctacgca ccggtgttgc tgctgcgcgc gcgcaagttc gcgctgctct      840

ggtcactggg ctcggcgctg gcgttggcgg gaagcgcgct gctgcggggc ggcgcggcgt      900

gcggacgcct gctgcgctgc gaagaagcgc cgtcccggcc cgcgctgctc tacatggcag      960

cgctgggcgc cacgctgttc gccgcgctgg gccttcgcag cacgctgctc acggtgctgg     1020

gcgcgggcgc gcaggtggcc gcgctgctgg ccgcgctggt tgggctgctg ccctggggcg     1080

gcggcaccgc gctgcgcctc gcactgggtc gcctgggccg cggcgccggc ctcgccaagg     1140

tgctgcccgt gtgaggacct cgcgccctcg ccgctgggga agtacgcgga gccagcgccg     1200

tcggagaccg cgccggccga gctgaggact gcacgccgct gtgcggaagc ccgtggcgaa     1260

ggccctgccc taacagcctg cgagtctaat ccgggagcgg ctgctgccag cggaggcgac     1320

agcagcgttg ggagctcctc gatgtcagct ttttgtgctg gacttggcac acgctctgaa     1380

aactgagatt ttgtcattga actggtgaca ggatgtgaga cggttattag aagttgcttt     1440

cgaagtaact gtggtcttag gttcggctga gtaaagaaaa aggatttttc ttcgagttag     1500

ctgctcttgt gatttttctc aggctgtttt gtcattttaa aatccagtgg tagatgtagc     1560

ttagcgacgg tagttttttg ttttggctat actaagactt ggaaattatt ctctccagtg     1620

tcagcgaatc cagaagggta tcagattaaa caccgaattc agccactgga cttttaaaag     1680

tacttaagat ggtttatctc gggttttttc ttcagttaac aaaatcataa atatggtgcc     1740

ttataacatg aaaggaaaat tagttgtgta tttcacgacg aaagcgacgg accaaaagaa     1800

atttcctgcc ccaagaagca tgggatccag gaaggggcgc gtagatgctt aacggtctct     1860

tcggaaatcc tgcaaataga aagataattc tagatccgga atacctgtat ctggtggaaa     1920

ccatggattt ctacaagctc gaattattcc tcattgtata gcctgctttg taaactagtt     1980

tacaatttgc aggctgatct taagattttt ttatatctaa ttgctgctgc cttcatttta     2040

ggttcagcag ttacttttaa ctaccttaat ttattgccag aaggtatgag cctaacattc     2100

tgatgagtcc agaaaactac gttttgtcag tagcaataca ctaggaagta aaatatattt     2160

agaatttaaa cattgtgtgc cagtggtcct cgcgcttgac tgcacatcag ttacttgaag     2220

agccacacct cagatcaatg cagtcagaac ctgggaagta ggtcccagac atcaggacct     2280

ttttaaagct ccccaagtga ttctacgttc cccaagtttg aggaccactt ttctgtgcat     2340

tggcttgcac aatttgaaaa taatgctttt cctgagctgg atcccagtgt tgccttaaca     2400

gggtgtctgt cgtgccgcag tagagcactg ctgcttcctc caaccccaaa atttatgttc     2460

ctaagtaagt caggtcccta agccccgtcc caagaagtga cacaagtggc caacatccac     2520

actgtaggct tgcaggctac ccgccctgag atttggtaaa gaacactgcc ttgttcccca     2580

tcagtaaaca aggttaccta cctcaggagg ctgcttgtga gagagcaaat gcagtatctt     2640

cagaatgatt tattttttta attaattgta aagacttgtg ccattggctg ctctttctag     2700

tcccctaaat ttctgttcta gttttaaatt tctctagaac ttgcaatagt tgggggtttt     2760

ataatgatgt tttacaatgt ttatttctta aataaaaact taaaaattca aaaaaaaaaa     2820

aaaa                                                                  2824


<210>  182
<211>  3534
<212>  DNA
<213>  homo sapiens

<400>  182
agtcaagagg cggggaggag aggaggaaaa agcgctgagt gagggcgggc gggcgggcgg       60

gagggaggga gtggaggagc cggggagggg ctccttaaag aaacgcttct gtcgctcgcc      120

tgctcgcttt tcgctcggca ttgcggccag ccagccgggc actcgggggg cacgcgcggc      180

caccgctaga gctctgcccc caccccaccc gccagcaggt ctggggtggg gacccaggtg      240

ggggctcctg cagccactgc ccggtgcgga ccgcacggag cgacccactc ctcccagcac      300

cgaggaagaa gcaacggagc cctcagcagg cgaccggcct ccccgcccct gaccacccgc      360

ttcccggctg cctttgtggc cgcagcttct cgccgccgag ccgagggccg gcgggggcgc      420

ggcgcgcacg gccgagcgat gcccagctcg ctgttcgcag acctggagcg caacggcagc      480

ggcggcggcg gcggcggcag cagcggaggg ggagagaccc tggatgacca aagagccctg      540

cagctcgcgc tcgaccagct ctccctgctg gggctggaca gtgacgaggg cgcctctctg      600

tacgacagcg agccgcgcaa gaagagcgtg aacatgaccg agtgcgtgcc agtacccagt      660

tctgagcatg tcgccgagat cgtggggcgg caaggttgta aaatcaaagc gctgcgggcg      720

aagaccaata cttacatcaa gaccccagtt cgcggggagg agcctgtctt tgttgtgacg      780

ggcaggaagg aggatgtggc catggctcgg agggagatca tctctgctgc cgagcacttc      840

tccatgatcc gcgcctcccg gaataagaac acggcactca acggcgcggt gcctgggccg      900

cccaacctgc ccgggcagac caccatccaa gtgcgggtac cctaccgcgt ggtggggctc      960

gtggtggggc ccaaaggcgc cacaatcaag cgcatccagc agcagacgca cacgtacatc     1020

gtgacgccca gccgggataa ggagccggtg ttcgaggtga ccggcatgcc agagaacgtg     1080

gatcgcgctc gagaggagat tgaggcgcac attgctctgc gtaccggcgg catcattgag     1140

ctcacagacg agaacgactt ccacgccaac ggcaccgatg tgggcttcga tctgcatcat     1200

gggtccggcg ggtccggccc aggcagcctc tggagcaagc ccacccccag catcacgccc     1260

acccccggcc gcaagccttt ctctagctac cgcaacgaca gctccagctc gcttggcagt     1320

gcttccacag actcttattt cggcggcggg accagcagca gcgcagcggc tacccagcgc     1380

ctggcggact acagcccccc tagccccgcc ctgagctttg cgcacaacgg aaacaataac     1440

aataacggca atgggtacac ctacacagcg gggggagaag cctcagtgcc atcccccgac     1500

ggctgccccg agctgcagcc cacttttgac ccggctcccg ctcccccacc tggggcacca     1560

cttatctggg cccagttcga gcggtccccg ggaggcggac ctgcagctcc ggtatcttct     1620

tcctgctctt cttctgcatc ttcgtctgct tcttcctcct ccgtggtctt ccccgggggt     1680

ggcgccagtg cgccctccaa cgccaacctg gggctattgg tgcaccgccg gctgcaccct     1740

ggcaccagct gcccgcgcct gtctccaccc ttgcacatgg ccccgggggc gggagagcac     1800

cacctggctc gccgggtgcg cagcgacccg ggtggaggag gcctggccta cgccgcttat     1860

gccaacgggc tgggggcaca gctgcctggc ttgcagccgt cggacacgtc gggctcctcc     1920

tcttcgtcca gctcctcctc cagctcttca tcctcttcct ccgggcttcg gcgtaaaggc     1980

agccgcgact gctccgtgtg cttcgagagc gaagtgattg ccgcgctggt gccctgtggc     2040

cacaacctct tctgcatgga gtgcgccaat cgcatctgtg agaagagcga gcccgagtgc     2100

ccggtctgcc acaccgcggt cactcaggcc atccgcatct tttcttaaag gcagcgggcg     2160

ctgctagtgc gcaccgtgct gggggaaggg ggaacccctc cccatcctct ttccccagcg     2220

ctcgcctgcc tccctgggtg ccccccctct cccttctcct tcccggcccc accaacactc     2280

tgagatccga gaggagcttg gaaagctgta gtatccgctc atttttaaaa tttaattttt     2340

aagtaaagga atttgccagg atatctgcat caagagtact gtagcctggg aaacctgaac     2400

acctgaaatg catgctctat aaataatagg aacggcgaca ttctagtaat gatagttttt     2460

acactgtact taataggaag cttccaaaag aagaaaaccc cacaagtttt ccattttctt     2520

aaagtaggaa aaaatgaaca gtaataatta tgatgaagat gatagtagtg ctatgggatg     2580

tgtggactgt ttagtgtgtt cccctttgtg ggtgggttcc tatgatactt attatagaac     2640

acagtggatc ctttttgaat gttcgtggaa gggccaggag ttcctgtgaa accaggatac     2700

tgcagcttta ttaaagttaa agaaactgta acatatctct tatatattaa aaacgtttaa     2760

aagttttaaa gagaaattgc attaatacag attgaagtat tttattcttt tttgacttga     2820

aaaattatat ttcatattgc aaagatgttt acaagtattt taatttaagt tcagtgaact     2880

tttttgtagc tgggttaaat ctttttattt tagtatggcc ttatggcaaa gaacactgta     2940

ttattttaat aatcacacaa ttgtgacgga attacaacca taaaatgtgt aatgttttga     3000

acagtattct gttgggatgg agattttata ggttcagaca aatcttctag atctgcttca     3060

cccagcatat tttctattca gtgatataaa gcatatttta ttctatatta ttacaaaaac     3120

ggaaatgtat aaacatgtca aaaagaactg ttgatgcttt ctaacatttg tataaataga     3180

attcagtgca agttacaaaa attctgttgc accactctag ttttagtatt tctattttaa     3240

tacatttgtt taccacttgt ttatgtatat gtaggtgatg ttacttgagc ttaaatgtac     3300

tttactgagc aaagtttaaa aaacaaagta tattttattt tatgataaag ggcctttaac     3360

ctcatggtca aatactaata ttatatttgc tgagacaaga tttgaaattg tatcaagagt     3420

tttatttttc tgacatttaa agttctacat aataaaggta aaacttaagt aatggtgcta     3480

cttcattttt taagtatttc tatataaata aaatattgaa gaaaatctta aaaa           3534


<210>  183
<211>  2331
<212>  DNA
<213>  homo sapiens

<400>  183
tgaggccagg agatggaggc tgcagtgagc tgtgatcaca ccactgtgct ccagcctgag       60

tgacagagca agaccctatc tcaaaaaaaa aaaaaaaaaa gaaaagctcc tgaggtgtag      120

acgccaactc tctctagctc gctagtgggt tgcaggaggt gcttacgcat gtttgtttct      180

ttgctgccgt cttccagttg ctttatctgt tcacttgtgc cctgactttc aactctgtct      240

ccttcctctt cctacagtac tcccctgccc tcaacaagat gttttgccaa ctggccaaga      300

cctgccctgt gcagctgtgg gttgattcca cacccccgcc cggcacccgc gtccgcgcca      360

tggccatcta caagcagtca cagcacatga cggaggttgt gaggcgctgc ccccaccatg      420

agcgctgctc agatagcgat ggtctggccc ctcctcagca tcttatccga gtggaaggaa      480

atttgcgtgt ggagtatttg gatgacagaa acacttttcg acatagtgtg gtggtgccct      540

atgagccgcc tgaggttggc tctgactgta ccaccatcca ctacaactac atgtgtaaca      600

gttcctgcat gggcggcatg aaccggaggc ccatcctcac catcatcaca ctggaagact      660

ccagtggtaa tctactggga cggaacagct ttgaggtgcg tgtttgtgcc tgtcctggga      720

gagaccggcg cacagaggaa gagaatctcc gcaagaaagg ggagcctcac cacgagctgc      780

ccccagggag cactaagcga gcactgccca acaacaccag ctcctctccc cagccaaaga      840

agaaaccact ggatggagaa tatttcaccc ttcagatgct acttgactta cgatggtgtt      900

acttcctgat aaactcgtcg taagttgaaa atattatccg tgggcgtgag cgcttcgaga      960

tgttccgaga gctgaatgag gccttggaac tcaaggatgc ccaggctggg aaggagccag     1020

gggggagcag ggctcactcc agccacctga agtccaaaaa gggtcagtct acctcccgcc     1080

ataaaaaact catgttcaag acagaagggc ctgactcaga ctgacattct ccacttcttg     1140

ttccccactg acagcctccc acccccatct ctccctcccc tgccattttg ggttttgggt     1200

ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac ccaggacttc catttgcttt     1260

gtcccggggc tccactgaac aagttggcct gcactggtgt tttgttgtgg ggaggaggat     1320

ggggagtagg acataccagc ttagatttta aggtttttac tgtgagggat gtttgggaga     1380

tgtaagaaat gttcttgcag ttaagggtta gtttacaatc agccacattc taggtagggg     1440

cccacttcac cgtactaacc agggaagctg tccctcactg ttgaattttc tctaacttca     1500

aggcccatat ctgtgaaatg ctggcatttg cacctacctc acagagtgca ttgtgagggt     1560

taatgaaata atgtacatct ggccttgaaa ccacctttta ttacatgggg tctagaactt     1620

gacccccttg agggtgcttg ttccctctcc ctgttggtcg gtgggttggt agtttctaca     1680

gttgggcagc tggttaggta gagggagttg tcaagtctct gctggcccag ccaaaccctg     1740

tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa tctcacccca tcccacaccc     1800

tggaggattt catctcttgt atatgatgat ctggatccac caagacttgt tttatgctca     1860

gggtcaattt cttttttctt tttttttttt ttttttcttt ttctttgaga ctgggtctcg     1920

ctttgttgcc caggctggag tggagtggcg tgatcttggc ttactgcagc ctttgcctcc     1980

ccggctcgag cagtcctgcc tcagcctccg gagtagctgg gaccacaggt tcatgccacc     2040

atggccagcc aacttttgca tgttttgtag agatggggtc tcacagtgtt gcccaggctg     2100

gtctcaaact cctgggctca ggcgatccac ctgtctcagc ctcccagagt gctgggatta     2160

caattgtgag ccaccacgtc cagctggaag ggtcaacatc ttttacattc tgcaagcaca     2220

tctgcatttt caccccaccc ttcccctcct tctccctttt tatatcccat ttttatatcg     2280

atctcttatt ttacaataaa actttgctgc cacctgtgtg tctgaggggt g              2331


<210>  184
<211>  3461
<212>  DNA
<213>  homo sapiens

<400>  184
actcgaagtg cggcgggaga ggcgggagcc caggagaggg tgcgggagct ggcggggcgg       60

ctcggagctg ccaggacgcc ctggtcccag ccgcgcacag gggagcgtgg acggcagagg      120

ggctcggcgg gagccgagat ccgcccgtcc cggctgcccc tcggcctccc tctgctccca      180

cctaccccct gacacccata gaaaagcgtg caaaggcgcg gagcgggacg gaaaccacaa      240

ataaatagcg gcggcggcag cgcgtcatct ggtggagcag gaagtgcagg cagagtccgg      300

aggctggtgc tttctgcgcg tccccaggac tttgccatgg gctgggggcc gcggaggctg      360

cgagcggccg ggcgagggca gcggcggcgg cgtccgcacc ggggctgagc gagcagcgac      420

gcgaggggcg cgcggagatg gcagcgtcca gcaactccag cctgtccggc tcgtcggtgt      480

cctccgatgc tgaagaatac cagcctccta tatggaaatc atacttatat cagttacagc      540

aagaggcacc tcgtcccaag agaatcattt gtcctcggga ggtggaaaac agaccaaaat      600

attatggaag agagtttcat gggatcatct ctcgggagca ggcggatgag cttcttggag      660

gcgtggaggg tgcctacatc cttagagaaa gccagcggca accaggatgc tacacgctgg      720

ctctcaggtt tggaaaccag accttaaact acaggctctt ccacgacggg aaacactttg      780

tgggtgagaa gaggtttgag tcgattcatg atctggtgac agatggcttg ataacactgt      840

acatagaaac aaaagctgcc gagtacattt caaaaatgac aactaacccc atctatgaac      900

acattggata tgccacccta ctcagagaaa aagtatccag aaggctgagc aggtctaaaa      960

atgaaccaag aaaaacaaac gtcacacatg aagaacacac agcggtggaa aagatctcct     1020

ccctggttcg aagggctgcc ctcacacaca acgacaacca cttcaattat gagaagacac     1080

acaactttaa ggtccacacg ttccgaggcc cacactggtg tgaatattgt gccaatttca     1140

tgtgggggct catcgcccaa ggggtccggt gctcagactg tggattgaac gtacacaaac     1200

agtgttccaa gcacgttccc aatgactgcc aacctgatct caagaggatc aagaaagtgt     1260

actgttgtga cctcacaaca cttgtgaagg ctcacaacac tcagagaccc atggtggtag     1320

acatatgcat tcgggaaatt gaagcaagag gattaaaatc ggaaggcctt tacagagtct     1380

ctgggttcac tgaacacatt gaagatgtca aaatggcatt tgacagagat ggtgaaaagg     1440

ccgatatatc tgccaatgtc tatccagaca taaacatcat cactggagcc cttaaactgt     1500

atttcagaga cttacccatc cctgtcatca catatgatac ctattccaaa tttatagatg     1560

cagcaaaaat ctccaatgca gatgagaggc tggaagccgt ccatgaagtg ctgatgctgc     1620

tgcctcctgc ccactatgaa accctccggt acctaatgat ccacctcaaa aaggttacta     1680

tgaatgaaaa agacaatttc atgaatgcag aaaatctggg gatcgtgttt gggcccactc     1740

tgatgaggcc ccctgaggac agcaccctga ccaccctgca tgatatgcgg taccaaaagc     1800

tgattgtgca gattttaata gaaaacgaag acgttttatt ctaatccatc agggaaatga     1860

gctgaatggc cccagcacca tccaagttga cacagctaaa ggaataaaaa catttcttac     1920

cacttgattt gttttccaag caagtgctag aatttgctgg actgcagagg atcgctgagt     1980

ggggtactgt gtctcataga catgcgccac ctccacgtga gaacaagggt gaaggtgagg     2040

gaagcccctc accttgggtc ttttgctgtg cctcctatgt atgtctggtt tgctggaaga     2100

gtgattaata catctttaat ttattaaaaa acaatgtaga cctttaaact tcagtcttat     2160

tggtaataaa agggaactta attcatacag gtacttgata cagttataca ttttccactt     2220

acaaaaagaa gacaattctg ttaaatgaaa cgtgtatcgt aaaatgtatt tttattttac     2280

ccacgagaat gttgttattt ttagcaaata gaactcaatg cagtgcattg gttattaccc     2340

tgtgtacctt gtccctcatt ttgctgtgac accctgaaaa agctgaccac aaatgcagta     2400

ttatcttgac atacctctgt cctcctcagt gctttttaat gaaatttcac ctgccccttg     2460

tgttcctgct ttggatagtt tttgctctta agcattggca ttcttctatt gtatggtatg     2520

tatttatagc aattgtagga tggtctgaaa tgtccacaca ctttctatgc atacaaattt     2580

tgtgaattcc caaagtatgc tttggaattg gtcatagtct tttcgtatca tgagtgtgta     2640

tcccagaaga tacagaatgc ggtcatttta cctgaaatta tttgagaaca ctggatgtat     2700

ctggtctgtg taaaaagtta gcacttaccc tcttttcttc ctggccaagc cctctgaatt     2760

catctgttaa tatcaaattg tatttttgcc acatttctgt attggtgaaa agcgaatctg     2820

cagaataact gtcaacgttt ttcattcttg ttttacaaac ctatttttta aagtgagaat     2880

aaggttggtt tttaccaaat atttgttcct ccttgacaaa agtagctctg tgtggataat     2940

atgattttat tactacagtt ccagtcactt ggttatattt atcttagcat gagcctttca     3000

caccaagatt tctatatttt gtaacatagg tgaaatattt aaaacatcaa aaactgtaaa     3060

tctagatttt taaaaaatcc aactgcaatg tcttttcctt tgattgagat gatttgtgta     3120

aactcaccag tcttgctttg gagtgagcag aagagaatga ctattttacg tggagcatca     3180

ttgtgtgact gttgacctgg acagtcccaa gggctatgca gatggactcc attggcacag     3240

ggaggtttga cctcttccct gctattatcc ctcctcccaa ctgtacagat ttgtttgttg     3300

tagtttatgt acttcttgat actgtcaaaa aattatctgg aaatggtttt attttgtgaa     3360

gtgaacaata ctttgtaatt tatgatagtg taaatggaag gcaaagcatc acatgtatta     3420

aattcttctg tctattattc tggaaaaaaa aaaaaaaaaa a                         3461


<210>  185
<211>  1744
<212>  DNA
<213>  homo sapiens

<400>  185
cagcgcccgg gccatggcgg cggcggtggc gggagctgct gtctgagcag cggttgcgga       60

ccgagcgaac ttggcccagg agcccgggcc tagggagagg cgcggcggcg gcgggagcgc      120

gaacggctgg agctggcctt cttcgccttc tcctcggctg tggagccctg gtggggggtc      180

tgcgcccggt caccatgacg acgccggcga atgcccagaa tgccagcaaa acgtgggaac      240

tgagtctgta tgagctgcac cggaccccgc aggaagccat aatggatggc acagagattg      300

ctgtttcccc tcggtcactg cattcagaac tcatgtgccc tatctgcctg gacatgctga      360

agaatacgat gaccaccaag gagtgcctcc acagattctg ctctgactgc attgtcacag      420

ccctacggag cgggaacaag gagtgtccta cctgccgaaa gaagctggtg tccaagcgat      480

ccctacggcc agaccccaac tttgatgccc tgatctctaa gatctatcct agccgggagg      540

aatacgaggc ccatcaagac cgagtgctta tccgcctgag ccgcctgcac aaccagcagg      600

cattgagctc cagcattgag gaggggctac gcatgcaggc catgcacagg gcccagcgtg      660

tgaggcggcc gataccaggg tcagatcaga ccacaacgat gagtgggggg gaaggagagc      720

ccggggaggg agaaggggat ggagaagatg tgagctcaga ctccgcccct gactctgccc      780

caggccctgc tcccaagcga ccccgtggag ggggcgcagg ggggagcagt gtagggacag      840

ggggaggcgg cactggtggg gtgggtgggg gtgccggttc ggaagactct ggtgaccggg      900

gagggactct gggaggggga acgctgggcc ccccaagccc tcctggggcc cccagccccc      960

cagagccagg tggagaaatt gagctcgtgt tccggcccca ccccctgctc gtggagaagg     1020

gagaatactg ccagacgagg tatgtgaaga caactgggaa tgccacagtg gaccacctct     1080

ccaagtactt ggccctgcgc attgccctcg agcggaggca acagcaggaa gcaggggagc     1140

caggagggcc tggagggggc gcctctgaca ccggaggacc tgatgggtgt ggcggggagg     1200

gtgggggtgc cggaggaggt gacggtcctg aggagcctgc tttgcccagc ctggagggcg     1260

tcagtgaaaa gcagtacacc atctacatcg cacctggagg cggggcgttc acgacgttga     1320

atggctcgct gaccctggag ctggtgaatg agaaattctg gaaggtgtcc cggccactgg     1380

agctgtgcta tgctcccacc aaggatccaa agtgacccca ccaggggaca gccagaggaa     1440

ggggaccatg gggtatccct gtgtcctggt ctatcacccc agcttctttg tcccccagta     1500

cccccagccc agccagccaa taagaggaca caaatgagga cacgtggctt ttatacaaag     1560

tatctatatg agattcttct atattgtaca gagtggggca aaacacgccc ccatctgctg     1620

ccttttctat tgccctgcaa cgtcccatct atacgaggtg ttggagaagg tgaagaaccc     1680

tcccattcac gcccgcctac caacaacaaa cgtgcttttt tcctctttga aacctgcaaa     1740

aaaa                                                                  1744


<210>  186
<211>  2284
<212>  DNA
<213>  homo sapiens

<400>  186
gctggaggaa gcggagtagg aagcggccgc gatgtccttt tgtgtcctac aagcagccgg       60

cggcgccgcc gagtgagggg acgcggcgcg gtggggcggc gcggcccgag gaggcggcgg      120

aggaggggcc gcccgcggcc cccggctcac tccggcactc cgggccgctc ggcccccatg      180

cctgcccgac cgcgctgccg gagccccagg tgaccagcgc catgtccagc caggtggtgg      240

gcattgagcc tctctacatc aaggcagagc cggccagccc tgacagtcca aagggttcct      300

cggagacaga gaccgagcct cctgtggccc tggcccctgg tccagctccc actcgctgcc      360

tcccaggcca caaggaagag gaggatgggg agggggctgg gcctggcgag cagggcggtg      420

ggaagctggt gctcagctcc ctgcccaagc gcctctgcct ggtctgtggg gacgtggcct      480

ccggctacca ctatggtgtg gcatcctgtg aggcctgcaa agccttcttc aagaggacca      540

tccaggggag catcgagtac agctgtccgg cctccaacga gtgtgagatc accaagcgga      600

gacgcaaggc ctgccaggcc tgccgcttca ccaagtgcct gcgggtgggc atgctcaagg      660

agggagtgcg cctggaccgc gtccggggtg ggcggcagaa gtacaagcgg cggccggagg      720

tggacccact gcccttcccg ggccccttcc ctgctgggcc cctggcagtc gctggaggcc      780

cccggaagac agcagcccca gtgaatgcac tggtgtctca tctgctggtg gttgagcctg      840

agaagctcta tgccatgcct gaccccgcag gccctgatgg gcacctccca gccgtggcta      900

ccctctgtga cctctttgac cgagagattg tggtcaccat cagctgggcc aagagcatcc      960

caggcttctc atcgctgtcg ctgtctgacc agatgtcagt actgcagagc gtgtggatgg     1020

aggtgctggt gctgggtgtg gcccagcgct cactgccact gcaggatgag ctggccttcg     1080

ctgaggactt agtcctggat gaagaggggg cacgggcagc tggcctgggg gaactggggg     1140

ctgccctgct gcaactagtg cggcggctgc aggccctgcg gctggagcga gaggagtatg     1200

ttctactaaa ggccttggcc cttgccaatt cagactctgt gcacatcgaa gatgccgagg     1260

ctgtggagca gctgcgagaa gctctgcacg aggccctgct ggagtatgaa gccggccggg     1320

ctggccccgg agggggtgct gagcggcggc gggcgggcag gctgctgctc acgctaccgc     1380

tcctccgcca gacagcgggc aaagtgctgg cccatttcta tggggtgaag ctggagggca     1440

aggtgcccat gcacaagctg ttcttggaga tgctcgaggc catgatggac tgaggcaagg     1500

ggtgggactg gtgggggttc tggcaggacc tgcctagcat ggggtcagcc ccaagggctg     1560

gggcggagct ggggtctggg cagtgccaca gcctgctggc agggccaggg caatgccatc     1620

agcccctggg aacaggcccc acgccctctc ctccccctcc tagggggtgt cagaagctgg     1680

gaacgtgtgt ccaggctctg ggcacagtgc tgccccttgc aagccataac gtgcccccag     1740

agtgtagggg gccttgcgga agccataggg ggctgcacgg gatgcgtggg aggcagaaac     1800

ctatctcagg gagggaaggg gatggaggcc agagtctccc agtgggtgat gcttttgctg     1860

ctgcttaatc ctaccccctc ttcaaagcag agtgggactt ggagagcaaa ggcccatgcc     1920

cccttcgctc ctcctctcat catttgcatt gggcattagt gtcccccctt gaagcaataa     1980

ctccaagcag actccagccc ctggacccct ggggtggcca gggcttcccc atcagctccc     2040

aacgagcctc ctcagggggt aggagagcac tgcctctatg ccctgcagag caataacact     2100

atatttattt ttgggtttgg ccagggaggc gcagggacat ggggcaagcc agggcccaga     2160

gcccttggct gtacagagac tctattttaa tgtatatttg ctgcaaagag aaaccgcttt     2220

tggttttaaa cctttaatga gaaaaaaata tataataccg agctcaaaaa aaaaaaaaaa     2280

aaaa                                                                  2284


<210>  187
<211>  1476
<212>  DNA
<213>  homo sapiens

<400>  187
ccccgccggg ctcgcgccgc agaggccggt gaggcgccgg cggccacgcc gcggaaggcg       60

cgggccgagc agagccgggc gttggagccc gcgcgcgcat ggaggcgttg ccggcagccc      120

cctgagggca gcggggagac aagacccggc gacctcgcgc atccctcgag ccgccacgcg      180

ctctcgccac cgggcggcga cgggccgcgg agccggcgcg gccatggcga cgggcggcca      240

gcagaaggag aacacgctgc ttcacctctt cgccggcggg tgtggaggca cagttggtgc      300

tattttcact tgtccactag aagtcattaa gacacggttg cagtcttcaa gattagctct      360

ccggacagtc tactatcctc aggttcatct ggggaccatt agtggagctg gaatggtgag      420

accaacatcc gtgacacctg gactctttca ggttctgaag tcgatcttgg agaaagaggg      480

accaaagtca ctttttagag gcttgggtcc aaatttggtt ggagttgcac catcaagggc      540

tgtatacttt gcatgttact ccaaagccaa agagcaattt aatggcattt tcgtgcctaa      600

cagcaatatt gtgcatattt tctcagctgg ctctgcagct tttatcacaa attccttaat      660

gaatcctata tggatggtta aaacccgaat gcagctagaa cagaaagtga ggggctctaa      720

gcagatgaat acactccagt gtgctcgtta cgtttaccag accgaaggca ttcgtggctt      780

ctatagagga ttaactgcct cgtatgctgg aatttccgaa actataatct gctttgctat      840

ttatgaaagt ttaaagaagt atctgaaaga agctccatta gcctcttctg caaatgggac      900

tgagaaaaat tccacaagtt tttttggact tatggcagct gctgctcttt ctaagggctg      960

tgcctcctgc attgcttatc cacacgaagt cataaggacg aggctccggg aagagggcac     1020

caagtacaag tcttttgtcc agacggcgcg cctggtgttc cgggaagaag gctaccttgc     1080

cttttataga ggactgtttg cccagcttat ccggcagatc ccaaatactg ccattgtgtt     1140

gtctacttat gagttaattg tgtacctgtt agaagaccgt actcagtaac aggccggaaa     1200

attgtgctct agaagaataa aactgaaaaa ctctagagaa ttttttttcc ccattgatgt     1260

ttagaaagtt tgagactgaa acaggaaagg ccataaaata tctggttcat atcacctgtt     1320

ggacatttcc ttttggattc atgctttctg gaaggtttaa attcattaac gttaatagtt     1380

aattataact ttttttttaa cttaagagga ttcagggtta agcaccaact aaattaaatc     1440

atgctattta atttaagtat aaaaaaaaaa aaaaaa                               1476


<210>  188
<211>  2817
<212>  DNA
<213>  homo sapiens

<400>  188
attggggtcg ggtcctcccc agtgagaggc gacaggagct cactgcctct cgggccctca       60

caatcacacc tgtcacaggt atacacgctg ccactcacaa acacacgctt gcactcccag      120

cctcactgac acgctgccat acagccgctc acagccagcc agacactgct gcacctgaga      180

gcaggtggcc gcgggtcttc tcccttcact ctccacattt ggggatcagg tccggcacct      240

gctgcgccag acaggccttg ctgggcacgc gcctctgaga gtccaaggag gtggcttcca      300

gagctgcagc acttcaggcc ggctccggtg gagcgatcag aggtgagggg cttggctggg      360

catgtttaag cgcacagtgc tctcctgccc acccccagca gcacccccac tgcaggcccg      420

aggagctttc cggagcttcc cacactcctg gggagaagac ttcttagcca gcttgatgtt      480

taaaattcag ctggagccct taaaacttcg agcgtggacg ctgaatgggt ttgtaaagtt      540

tcgaaacaag gagaccagtg ctggtccagt ggctgtgatg ggaaaagatt attacaagat      600

tcttgggatc ccatcggggg ccaacgagga tgagatcaag aaagcctacc ggaagatggc      660

cttgaagtac cacccagaca agaataaaga acccaacgct gaggagaagt ttaaggagat      720

tgcagaggcc tatgatgtgc taagtgaccc caagaaacgg ggcctgtatg accagtatgg      780

ggaggaaggc ctgaagaccg gcggtggcac atcaggtggc tccagtggct cctttcacta      840

cacctttcat ggggaccccc atgccacctt tgcctccttc tttggtggct ccaacccctt      900

cgatatcttc tttgccagca gccgctccac tcggcccttc agtggctttg acccagatga      960

catggatgtg gatgaagatg aggacccatt tggcgctttc ggccgttttg gcttcaatgg     1020

gctgagtagg ggtccaaggc gagccccaga accactgtac cctcggcgca aggtgcagga     1080

ccccccagtg gtgcacgagc tgcgggtgtc cctggaggag atctaccatg gctccaccaa     1140

gcgcatgaag atcacaaggc gtcgcctcaa ccctgatggg cgaactgtgc gcaccgagga     1200

caagatcctg cacatagtca tcaagcgtgg ctggaaggaa ggcaccaaga tcaccttccc     1260

caaagaaggc gacgccacac ctgacaacat ccctgctgac atcgtctttg tgctcaaaga     1320

caagccccat gcacacttcc gccgagatgg caccaacgtg ctctacagtg ccctgatcag     1380

cctcaaggag gcgctgtgtg gctgcactgt gaacattccc actatcgacg gccgagtgat     1440

ccctttgccc tgcaatgatg tcatcaagcc aggcaccgtg aagagactcc gtggggaggg     1500

ccttcccttc cccaaagtgc caactcagcg aggagacctc attgttgagt tcaaagttcg     1560

cttcccagac agattaacac cacagacaag acagatcctt aagcagcacc taccctgttc     1620

ctaggctctg ccccagccag tccagagcct accacagcaa tacccccaac actcactcca     1680

ctcaatgtgc acccagcttg atgtccactg gacactggca actttttcta aaatgcaaaa     1740

aaaagccact ggttttcagg aaaatgttcc tgtccctgac cccttttaga gctgggctgc     1800

ctggggggag tgggagggag gtggggagag ctagcccagg ccaggggtca atgttcatgt     1860

cactagcttt caatccagtt tccactgcag tggctggaga gtgacctgag tgctacttga     1920

agatatgtag agattcctta tccatgcctg tacatagcat gtcctcctcc cctcagcttt     1980

gctaatacca gtcccctccc ttccctttgg cttcctgctg ttgggggtgg aaaagactag     2040

aaaggacatt gctttctcag ccccaccccc aggtccacag tgtccaaggt aatggcacac     2100

atattcatgc acaagaagca ctcacctaga gctgtctgtg cctctctggg agaaaggaga     2160

gaggataaga agggaaagtt cacaacctgt gaacagggac ttgagcacga gacacttttc     2220

atctggagca ggggggtgag ctcctcagca gcctccgtaa cagctgccct gcctacacct     2280

gcagagctgg aggttctgtc ctccctgctg ctctcaggag tgttcaaggg tggagggcag     2340

ggaatggggc ctgaggtatt aaggctaaga ggtgggggac agggcccatc taccagcctt     2400

catcaggaag ggaaagggct ttggggtcag gtggcagcta ttccccacca agagattcag     2460

ggtcacaggt ttttccccac acctctgaac tcagggccta gccaccccca aacttccaaa     2520

tcccactttt gtgatatgtg aagctactca tttcttaccc ttggaggctg tgtggggaat     2580

ttccagccct tttatgcctg tgtgatccca ccccaccccc atagttgtat aaaggtcata     2640

gtgaagaagc tgggggaaga ctgcttcagc cagatcctgg ggtggggtct ttaggttttc     2700

tcactttgac aacccccgaa tgtttttata gtagtttttt tgtatttttt tgtaatgaca     2760

gtattatgta aaaaataaag tattttaaaa atatggcaaa aaaaaaaaaa aaaaaaa        2817


<210>  189
<211>  2953
<212>  DNA
<213>  homo sapiens

<400>  189
gagctcgccg tcgctccgtc atagagttcg ccccacccca tcccctcctt tctggactcg       60

gagctcagtt cacgcagtaa caaatgaagt gcgcgctgcg acacctccca gcccaccgaa      120

ctccgccgcc atttcctcgc ttggcctaac ggttcggcca atcccagcgc gcatcaagaa      180

ggactgaggc tccgccaatc ggaggccgcc gatttcgacc cttcgcctcg gcccggccca      240

atccaggccc cggccccgcc gcccccggcc cgcccccgcg gtgccctctc tcctccctct      300

ttgtgcgtct cgcgccgccg ccgcccgccg cgtgagagga cgggctccgc gcgctccggc      360

agcgcattcg ggtcccctcc ccccgggagg cttgcgaagg agaagccgcc gcagaggaaa      420

agcaggtgcc ggtgcctgtc cccgggggcg ccatggcgac cggagcgaac gccacgccgt      480

tggacttccc aagtaagaag cggaagagga gccgctggaa ccaagacaca atggaacaga      540

agacagtgat tccaggaatg cctacagtta ttccccctgg acttactcga gaacaagaaa      600

gagcttatat agtgcaactg cagatagaag acctgactcg taaactgcgc acaggagacc      660

tgggcatccc ccctaaccct gaggacaggt ccccttcccc tgagcccatc tacaatagcg      720

aggggaagcg gcttaacacc cgagagttcc gcacccgcaa aaagctggaa gaggagcggc      780

acaacctcat cacagagatg gttgcactca atccggattt caagccacct gcagattaca      840

aacctccagc aacacgtgtg agtgataaag tcatgattcc acaagatgag tacccagaaa      900

tcaactttgt ggggctgctc atcgggccca gagggaacac cctgaagaac atagagaagg      960

agtgcaatgc caagattatg atccggggga aagggtctgt gaaagaaggg aaggttgggc     1020

gcaaagatgg ccagatgttg ccaggagaag atgagccact tcatgccctg gttactgcca     1080

atacaatgga gaacgtcaaa aaggcagtgg aacagataag aaacatcctg aagcagggta     1140

tcgagactcc agaggaccag aatgatctac ggaagatgca gcttcgggag ttggctcgct     1200

taaatgggac ccttcgggaa gacgataaca ggatcttaag accctggcag agctcagaga     1260

cccgcagcat taccaacacc acagtgtgta ccaagtgtgg aggggctggc cacattgctt     1320

cagactgtaa attccaaagg cctggtgatc ctcagtcagc tcaggataaa gcacggatgg     1380

ataaagaata tttgtccctc atggctgaac tgggtgaagc acctgtccca gcatctgtgg     1440

gctccacctc tgggcctgcc accacacccc tggccagcgc acctcgtcct gctgctcccg     1500

ccaacaaccc acctccaccg tctctcatgt ctaccaccca gagccgccca ccctggatga     1560

attctggccc ttcagagagt cggccctacc acggcatgca tggaggtggt cctggtgggc     1620

ccggaggtgg cccccacagc ttcccacacc cattacccag cctgacaggt gggcatggtg     1680

gacatcccat gcagcacaac cccaatggac ccccaccccc ttggatgcag ccaccaccac     1740

caccgatgaa ccagggcccc caccctcctg ggcaccatgg ccctcctcca atgggtaaat     1800

cagtacctgg gaagtacgcc tgtgggctct ggggtctatc gcctgcatca aggaaaaggt     1860

atgatgccgc caccacctat gggcatgatg ccgccgccgc cgccgcctcc cagtgggcag     1920

cccccacccc ctccctctgg tcctcttccc ccatggcaac aacagcagca gcagcctccg     1980

ccaccccctc cgcccagcag cagtatggct tccagtaccc ccttgccatg gcagcaaaga     2040

tccctccccg cggcggcgat ggcccgagcc atgagagtga ggactttccg cgcccattgg     2100

tgacccttcc aggcagacag cctcagcaac gcccctggtg gacaggatgg ttcggcaaag     2160

cagcctgagt tatttttgtg gacggaatcg gaacacgctg gctccatatc gtgaaatttt     2220

tattaatttt tttctttttc ctttgttact tctttatctt ttcctttctt cagactccgt     2280

ccaaggagat gctctccccg gtcttctgct gcaatttaga ttcctttccc ttctctccag     2340

ttctccttcc cttaccaagg agaggggagc aaatggtttt gggcaagggc tttggccatt     2400

catgtcaagc tggttgtggg tttttcaagg tgccatagcc acccccaaag atgtttgttt     2460

aaagcgtggg gttttttaat ctctgccacc cttgtcaagg gagtcttgta aagttgccga     2520

gggtaggttc atctccaggt ttcgggattc ccatccgtcc tggcgatcct gccagcagtg     2580

ggtgggcagc ctgagctccc tcgggctcgc ctgccagcct ggagttcttc ctgtgctcct     2640

tgatcacctg agctgcctca gattccattt ggtcctctcc ttcctggaag gcttcctttt     2700

atgttttgtt ttaatcccaa atgtctgaat gttttgcagt gtgtaggggt ttgagcccct     2760

tgttcattct ccttcctttt tcctcccgct tccctctcca tgaagtgatt ctgttgacaa     2820

taatgtatac tgcgcgttct cttcactggt ttatctgcag aaatttctct gggctttttt     2880

cggtgttaga ttcaacactg cgctaaagcg gggatgttcc attgaataaa agagcagtgt     2940

ggttttctgg gtc                                                        2953


<210>  190
<211>  3063
<212>  DNA
<213>  homo sapiens

<400>  190
ccgaggggcg gtccctgggc tcccgctcgc cgccgctgcc gctcctcgtt ctgctcctca       60

ctccccagcg gctggaggcc ggtaccggcg ggcaggaggc gcccgaggat gtgctgctgg      120

ccgctgctcc tgctgtgggg gctgctcccc gggacggcgg cggggggctc gggccgaacc      180

tatccgcacc ggaccctcct ggactcggag ggcaagtact ggctgggctg gagccagcgg      240

ggcagccaga tcgccttccg cctccaggtg cgcactgcag gctacgtggg cttcggcttc      300

tcgcccaccg gggccatggc gtccgccgac atcgtcgtgg gcggggtggc ccacgggcgg      360

ccctacctcc aggattattt tacaaatgca aatagagagt tgaaaaaaga tgctcagcaa      420

gattaccatc tagaatatgc catggaaaat agcacacaca caataattga atttaccaga      480

gagctgcata catgtgacat aaatgacaag agtataacgg atagcactgt gagagtgatc      540

tgggcctacc accatgaaga tgcaggagaa gctggtccca agtaccatga ctccaatagg      600

ggcaccaaga gtttgcggtt attgaatcct gagaaaacta gtgtgctatc tacagcctta      660

ccatactttg atctggtaaa tcaggacgtc cccatcccaa acaaagatac aacatattgg      720

tgccaaatgt ttaagattcc tgtgttccaa gaaaagcatc atgtaataaa ggttgagcca      780

gtgatacaga gaggccatga gagtctggtg caccacatcc tgctctatca gtgcagcaac      840

aactttaacg acagcgttct ggagtccggc cacgagtgct atcaccccaa catgcccgat      900

gcattcctca cctgtgaaac tgtgattttt gcctgggcta ttggtggaga gggcttttct      960

tatccacctc atgttggatt atcccttggc actccattag atccgcatta tgtgctccta     1020

gaagtccatt atgataatcc cacttatgag gaaggcttaa tagataattc tggactgagg     1080

ttattttaca caatggatat aaggaaatat gatgctgggg tgattgaggc tggcctctgg     1140

gtgagcctct tccataccat ccctccaggg atgcctgagt tccagtctga gggtcactgc     1200

actttggagt gcctggaaga ggctctggaa gccgaaaagc caagtggaat tcatgtgttt     1260

gctgttcttc tccatgctca cctggctggc agaggcatca ggctgcgtca ttttcgaaaa     1320

gggaaggaaa tgaaattact tgcctatgat gatgattttg acttcaattt ccaggagttt     1380

cagtatctaa aggaagaaca aacaatctta ccaggagata acctaattac tgagtgtcgc     1440

tacaacacga aagatagagc tgagatgact tggggaggac taagcaccag gagtgaaatg     1500

tgtctctcat accttcttta ttacccaaga attaatctta ctcgatgtgc aagtattcca     1560

gacattatgg aacaacttca gttcattggg gttaaggaga tctacagacc agtcacgacc     1620

tggcctttca ttatcaaaag tcccaagcaa tataaaaacc tttctttcat ggatgctatg     1680

aataagttta aatggactaa aaaggaaggt ctctccttca acaagctggt cctcagcctg     1740

ccagtgaatg tgagatgttc caagacagac aatgctgagt ggtcgattca aggaatgaca     1800

gcattacctc cagatataga aagaccctat aaagcagaac ctttggtgtg tggcacgtct     1860

tcttcctctt ccctgcacag agatttctcc atcaacttgc ttgtttgcct tctgctactc     1920

agctgcacgc tgagcaccaa gagcttgtga tcaaaattct gttggacttg acaatgtttt     1980

ctatgatctg aacctgtcat ttgaagtaca ggttaaagac tgtgtccact ttgggcatga     2040

agagtgtgga gacttttctt ccccattttc cctccctcct ttttcctttc catgttacat     2100

gagagacatc aatcaggttc tcttctcttt cttagaaata tctgatgtta tatatacatg     2160

gtcaataaaa taaaactggc ctgacttaag ataaccattt taaaaaattg ggctgtcatg     2220

tgggaataaa agaattcttt ctttcctact acattctgtt ttatttaaat actcattgtt     2280

gctatttcac tttttgactt gacttttata tttctttaaa aaattccttc cttttaaaaa     2340

atataaaagg gactactgtt cattccagtt ttcttcttct ttgttgttct tctagtgtga     2400

cttttcaagt gtaacagcca ttcttcctga ctttaatatt gtccagttct ggtcttttct     2460

gtgaattacc actgggcccc ttacctcaat gctttttgtt gatgcccact ctggttccct     2520

tgtttatctg agtctgttgg taccccaaat gaccccacac ccatcttaaa gtactttttt     2580

tcaccttccc tgtttagtac tggccagatg agttttttct agagctctgt cactatctga     2640

aaagaaagag gctatgggaa acatagaaat ggtatgtatt aataactgat cataggctga     2700

ggagaaaaaa tgtagctggc tgcaaaccca gtgctgtgag gtgacttata tgaggttcca     2760

gatcaaagac aggccgtgtg agccagtcca ggagggtgta agttctgaat ggttccttgc     2820

tgactttggg tgacacatgt accacatact ggctcagttt aagtcatggt tctattgtag     2880

atttattttt atattagtta ataaatgact ttaaattgtc accaattgaa aatcttgtca     2940

ctcttttggt tttctttata tagctcagcc aaatcttgtt ttatgtcctg tcctcatctc     3000

ttaagctaaa tctgtttgga tcatattaat aaactaaatg aaattacaaa aaaaaaaaaa     3060

aaa                                                                   3063


<210>  191
<211>  3198
<212>  DNA
<213>  homo sapiens

<400>  191
atttgaggtg ttctgaccag aagaagacag agcggatgat cattcattca ccacgttgac       60

aacctcgcct gtgattgaca gctggagtgg cagaaagcca tgagatttgg tagttgggtc      120

tgaggggcgc tctttttttt ccttttcttt ctttctttct tttttttttt ttaaactgat      180

ttttggggga gagaagatct gctttttttt gcccccgctg ctgtcttgga aacggagcgc      240

ttttatgctc agtgactcgg gcgctttgct tcaggtcccg tagaccgaag atctgggacc      300

agtagctcac gttgctggag acgttaaggg atttttcgtc gtgctttttt tttttttttt      360

ttttttttcc gggggagttt gaatatttgt ttcttttcac actggcctta aagaggatat      420

attagaagtt gaagtaggaa gggagccaga gaggccgatg gcgcaaaggt acgacgatct      480

accccattac gggggcatgg atggagtagg catcccctcc acgatgtatg gggacccgca      540

tgcagccagg tccatgcagc cggtccacca cctgaaccac gggcctcctc tgcactcgca      600

tcagtacccg cacacagctc ataccaacgc catggccccc agcatgggct cctctgtcaa      660

tgacgcttta aagagagata aagatgccat ttatggacac cccctcttcc ctctcttagc      720

actgattttt gagaaatgtg aattagctac ttgtaccccc cgcgagccgg gggtggcggg      780

cggggacgtc tgctcgtcag agtcattcaa tgaagatata gccgtgttcg ccaaacagat      840

tcgcgcagaa aaacctctat tttcttctaa tccagaactg gataacttga tgattcaagc      900

catacaagta ttaaggtttc atctattgga attagagaag gtacacgaat tatgtgacaa      960

tttctgccac cggtatatta gctgtttgaa agggaaaatg cctatcgatt tggtgataga     1020

cgatagagaa ggaggatcaa aatcagacag tgaagatata acaagatcag caaatctaac     1080

tgaccagccc tcttggaaca gagatcatga tgacacggca tctactcgtt caggaggaac     1140

cccaggccct tccagcggtg gccacacgtc acacagtggg gacaacagca gtgagcaagg     1200

tgatggcttg gacaacagtg tagcttcccc cagcacaggt gacgatgatg accctgataa     1260

ggacaaaaag cgtcacaaaa agcgtggcat ctttcccaaa gtagccacaa atatcatgag     1320

ggcgtggctg ttccagcatc taacacaccc ttacccttct gaagaacaga aaaagcagtt     1380

ggcacaagac acgggactca ccatccttca agtgaacaat tggtttatta atgcccggag     1440

aagaatagtg cagcccatga tagaccagtc caaccgagca gtaagtcaag gaacacctta     1500

taatcctgat ggacagccca tgggaggttt cgtaatggac ggtcagcaac atatgggaat     1560

tagagcacca ggacctatga gtggaatggg catgaatatg ggcatggagg ggcagtggca     1620

ctacatgtaa ccttcatcta gttaaccaat cgcaaagcaa gggggaaggc tgcaaagtat     1680

gccaggggag tatgtagccc ggggtggtcc aatgggtgtg agtatgggac agccaagtta     1740

tacccaaccc cagatgcccc cccatcctgc tcagctgcgt catgggcccc ccatgcatac     1800

gtacattcct ggacaccctc accacccaac agtgatgatg catggaggac cgccccaccc     1860

tggaatgcca atgtcagcat caagccccac agttcttaat acaggagacc caacaatgag     1920

tggacaagtc atggacattc atgctcagta gcttaaggga atatgcattg tctgcaatgg     1980

tgactgattt caaatcatgt tttttctgca atgactgtgg agttccattc ttggcatcta     2040

ctctggacca aggagcatcc ctaattcttc atagggacct ttaaaaagca ggaaatacca     2100

actgaagtca atttggggga catgctaaat aactatataa gacattaaga gaacaaagag     2160

tgaaatattg taaatgctat tatactgtta tccatattac gttgtttctt atagattttt     2220

taaaaaaaat gtgaaatttt tccacactat gtgtgttgtt tccatagctc ttcacttcct     2280

ccagaagcct ccttacatta aaaagcctta cagttatcct gcaagggaca ggaaggtctg     2340

atttgcagga tttttagagc attaaaataa ctatcaggca gaagaatctt tcttctcgcc     2400

taggatttca gccatgcgcg cgctctctct ctttctctct cttttcctct ctctccctct     2460

ttctagcctg gggcttgaat ttgcatgtct aattcattta ctcaccatat ttgaattggc     2520

ctgaacagat gtaaatcggg aaggatggga aaaactgcag tcatcaacaa tgattaatca     2580

gctgttgcag gcagtgtctt aaggagactg gtaggaggag gcatggaaac caaaaggccg     2640

tgtgtttaga agcctaattg tcacatcaag catcattgtc cccatgcaac aaccaccacc     2700

ttatacatca cttcctgttt taagcagctc taaaacatag actgaagatt tatttttaat     2760

atgttgactt tatttctgag caaagcatcg gtcatgtgtg tattttttca tagtcccacc     2820

ttggagcatt tatgtagaca ttgtaaataa attttgtgca aaaaggactg gaaaaatgaa     2880

ctgtattatt gcaatttttt tttgtaaaag tagcagtttg gtatgagttg gcatgcatac     2940

aagatttact aagtgggata agctaattat actttttgtt gtggataaac aaatgcttgt     3000

tgatagcctt tttctatcaa gaaaccaagg agctaattat taataacaat cattgcacac     3060

tgagtcttag cgtttctgat ggaaacagtt tggattgtat aataacgcca agcccagttg     3120

tagtcgtttg agtgcagtaa tgaaatctga atctaaaata aaaacaagat tatttttgtc     3180

aaaaaaaaaa aaaaaaaa                                                   3198


<210>  192
<211>  2849
<212>  DNA
<213>  homo sapiens

<400>  192
tcctcctcct ctcttctctc ttacctccct ccctctctct catctttatc ccttcctctc       60

ttttctgttc gccctcttct ccctgctctt tttccctttc cacccccctc ctctgttctc      120

cctcacctcc tgcgccccct cccccttccc gggttctgac agtacgatga gctgccccat      180

tacggcggga tggacggagt aggggttccc gcttccatgt acggagaccc tcacgcgccg      240

cggccgatcc ccccggttca ccacctgaac cacgggccgc cgctccacgc cacacagcac      300

tacggcgcgc acgccccgca ccccaatgtc atgccggcca gtatgggatc cgctgtcaac      360

gacgccttga agcgggacaa ggacgcgatc tatgggcacc cgttgtttcc tctgttagct      420

ctggtctttg agaagtgcga gctggcgacc tgcactcccc gggaacctgg agtggctggc      480

ggagacgtct gctcctccga ctccttcaac gaggacatcg cggtcttcgc caagcaggtt      540

cgcgccgaaa agccactttt ttcctcaaat ccagagctgg acaatttgat gatacaagca      600

atacaagtac taaggtttca tcttttggag ttagaaaagg tccacgaact gtgcgataac      660

ttctgccacc gatacattag ctgtttgaag gggaaaatgc ccatcgacct cgtcattgat      720

gaaagagacg gcagctccaa gtcagatcat gaagaacttt caggctcctc cacaaatctc      780

gctgaccata acccttcttc ttggcgagac cacgatgatg caacctcaac ccactcagca      840

ggcaccccag ggccctccag tgggggccat gcttcccaga gcggagacaa cagcagtgag      900

caaggggatg gtttagacaa cagtgtagct tcacctggta caggtgacga tgatgatccg      960

gataaggaca aaaaacgcca gaagaaaaga ggcattttcc ccaaagtagc aacaaatatc     1020

atgagagcat ggctcttcca gcatctcaca catccgtacc cttccgaaga gcagaagaaa     1080

cagttagcgc aagacacagg acttacaatt ctccaagtaa acaactggtt tattaatgcc     1140

agaagaagaa tagtacagcc catgattgac cagtcaaatc gagcaggttt tcttcttgat     1200

ccttcagtga gccaaggagc agcatatagt ccagagggtc agcccatggg gagctttgtg     1260

ttggatggtc agcaacacat ggggatccgg cctgcaggac ctatgagtgg aatgggcatg     1320

aatatgggca tggatgggca atggcactac atgtaacctt catcatgtaa agcaatcgca     1380

aagcaagggg gaagtttgca gagcatgcca ggggactacg tttctcaggg tggtcctatg     1440

ggaatgagta tggcacagcc aagttacact cctccccaga tgaccccaca ccctactcaa     1500

ttaagacatg gacccccaat gcattcatat ttgccaagcc atccccacca cccagccatg     1560

atgatgcacg gaggaccccc tacccaccct ggaatgacta tgtcagcaca gagccccaca     1620

atgttaaatt ctgtagatcc caatgttggc ggacaggtta tggacattca tgcccaatag     1680

tataagggaa ctcaagggaa aaggaaacac acgcaaaaac tattttaaga ctttctgaac     1740

tttgaccaga tgttgacact taatatgaaa ttccagacag ctgtgattat tttttacttt     1800

tgtcattttt catcaagcaa cagaggacca atgcaacaag aacacaaatg tgaaatcatg     1860

ggctgactga gacaattctg tccatgtaaa gatcctctgg aaaaagactc cgagagttat     1920

aactactgta gtataaatat aggaactaag ttaaacttgt acatttctgt tgatcacgcc     1980

gttatgttgc ctcaaatagt tttagaagag aaaaaaaaat atatccttgt tttccacact     2040

atgtgtgttg ttcccaaaag aatgactgtt ttggttcatc agtgaattca ccatccagga     2100

gagactgtgg tatatatttt aaacctgttg ggccaatgag aaaagaacca cactggagat     2160

catgatgaac ttttggctga acctcatcac tcgaactcca gcttcaagaa tgtgttttca     2220

tgcccggcct ttgttcctcc ataaatgtgt cctttagttt caaacagatc tttatagttc     2280

gtgcttcata agccaattct tattattatt tttgggggac tcttcttcaa agagcttgcc     2340

aatgaagatt taaagacaga gcaggagctt cttccaggag ttctgagcct tggttgtgga     2400

caaaacaatc ttaagttggg cagctttcct caacacaaaa aaaagttatt aatggtcatt     2460

gaaccataac taggacttta tcagaaactc aaagcttggg ggataaaaag gagcaagaga     2520

atactgtaac aaacttcgta cagagttcgg tctattaatt gtttcatgtt agatattcta     2580

tgtgtttacc tcaattgaaa aaaaaaagaa tgtttttgct agtatcagat ctgctgtgga     2640

attggtattg tatgtccatg aattcttctt ttctcagcac gtgttcctca ctagaagaaa     2700

atgctgttac ctttaagctt tgtcaaattt acattaaaat acttgtatga ggactgtgac     2760

gttatgttaa aaaaaaaaag gtgttaagtc acaaaaagcg gtaataaata tttcattttt     2820

gattttttgt taaaaaaaaa aaaaaaaaa                                       2849


<210>  193
<211>  3139
<212>  DNA
<213>  homo sapiens

<400>  193
cccgatgcct cctctccctt caacgcttct gctgctgctc gctgcttgat gatggcggcc       60

agtattttaa aaaatagcaa aattattcat cggcttcttt ccctcccgtg cctctgcgtg      120

tgtgcgagtg tgtgtgcgtg cgtgtgtgcg tgtctgggcg cgcgtgttcc agcgctgtgc      180

gagcgggcgg gcggcgagtg cgtgtgagtg gtgtgtgtgt gtgcgtgtgc aatcgttaca      240

cgctttcgcc tcgctccagc ttttacccca gcagcgcgat tcccccggtt ctcctgctgc      300

cgctgctgcg ccgctgccgc cgtggctcgc gcggctcggg gcgggcacgg gctgcgtagg      360

agccgccgcc ggggccgccg ctggggccgc gctgccgcag ccgctgcgcc gccgcctaga      420

ctactagcct gggctgcttg ttttgtctct gaaattgaca aggacgcagg gaatccgctg      480

ctaaataatg tttctgtacg atgagctgcc ccattacggc gggatggacg gagtaggggt      540

tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg ttcaccacct      600

gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc cgcaccccaa      660

tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg acaaggacgc      720

gatctatggc tctggtcttt gagaagtgcg agctggcgac ctgcactccc cgggaacctg      780

gagtggctgg cggagacgtc tgctcctccg actccttcaa cgaggacatc gcggtcttcg      840

ccaagcaggt tcgcgccgaa aagccacttt tttcctcaaa tccagagctg gacaatttga      900

tgatacaagc aatacaagta ctaaggtttc atcttttgga gttagaaaag gtccacgaac      960

tgtgcgataa cttctgccac cgatacatta gctgtttgaa ggggaaaatg cccatcgacc     1020

tcgtcattga tgaaagagac ggcagctcca agtcagatca tgaagaactt tcaggctcct     1080

ccacaaatct cgctgaccat aacccttctt cttggcgaga ccacgatgat gcaacctcaa     1140

cccactcagc aggcacccca gggccctcca gtgggggcca tgcttcccag agcggagaca     1200

acagcagtga gcaaggggat ggtttagaca acagtgtagc ttcacctggt acaggtgacg     1260

atgatgatcc ggataaggac aaaaaacgcc agaagaaaag aggcattttc cccaaagtag     1320

caacaaatat catgagagca tggctcttcc agcatctcac acatccgtac ccttccgaag     1380

agcagaagaa acagttagcg caagacacag gacttacaat tctccaagta aacaactggt     1440

ttattaatgc cagaagaaga atagtacagc ccatgattga ccagtcaaat cgagcagtga     1500

gccaaggagc agcatatagt ccagagggtc agcccatggg gagctttgtg ttggatggtc     1560

agcaacacat ggggatccgg cctgcaggac ctatgagtgg aatgggcatg aatatgggca     1620

tggatgggca atggcactac atgtaacctt catcatgtaa agcaatcgca aagcaagggg     1680

gaagtttgca gagcatgcca ggggactacg tttctcaggg tggtcctatg ggaatgagta     1740

tggcacagcc aagttacact cctccccaga tgaccccaca ccctactcaa ttaagacatg     1800

gacccccaat gcattcatat ttgccaagcc atccccacca cccagccatg atgatgcacg     1860

gaggaccccc tacccaccct ggaatgacta tgtcagcaca gagccccaca atgttaaatt     1920

ctgtagatcc caatgttggc ggacaggtta tggacattca tgcccaatag tataagggaa     1980

ctcaagggaa aaggaaacac acgcaaaaac tattttaaga ctttctgaac tttgaccaga     2040

tgttgacact taatatgaaa ttccagacag ctgtgattat tttttacttt tgtcattttt     2100

catcaagcaa cagaggacca atgcaacaag aacacaaatg tgaaatcatg ggctgactga     2160

gacaattctg tccatgtaaa gatcctctgg aaaaagactc cgagagttat aactactgta     2220

gtataaatat aggaactaag ttaaacttgt acatttctgt tgatcacgcc gttatgttgc     2280

ctcaaatagt tttagaagag aaaaaaaaat atatccttgt tttccacact atgtgtgttg     2340

ttcccaaaag aatgactgtt ttggttcatc agtgaattca ccatccagga gagactgtgg     2400

tatatatttt aaacctgttg ggccaatgag aaaagaacca cactggagat catgatgaac     2460

ttttggctga acctcatcac tcgaactcca gcttcaagaa tgtgttttca tgcccggcct     2520

ttgttcctcc ataaatgtgt cctttagttt caaacagatc tttatagttc gtgcttcata     2580

agccaattct tattattatt tttgggggac tcttcttcaa agagcttgcc aatgaagatt     2640

taaagacaga gcaggagctt cttccaggag ttctgagcct tggttgtgga caaaacaatc     2700

ttaagttggg cagctttcct caacacaaaa aaaagttatt aatggtcatt gaaccataac     2760

taggacttta tcagaaactc aaagcttggg ggataaaaag gagcaagaga atactgtaac     2820

aaacttcgta cagagttcgg tctattaatt gtttcatgtt agatattcta tgtgtttacc     2880

tcaattgaaa aaaaaaagaa tgtttttgct agtatcagat ctgctgtgga attggtattg     2940

tatgtccatg aattcttctt ttctcagcac gtgttcctca ctagaagaaa atgctgttac     3000

ctttaagctt tgtcaaattt acattaaaat acttgtatga ggactgtgac gttatgttaa     3060

aaaaaaaaag gtgttaagtc acaaaaagcg gtaataaata tttcattttt gattttttgt     3120

taaaaaaaaa aaaaaaaaa                                                  3139


<210>  194
<211>  2542
<212>  DNA
<213>  homo sapiens

<400>  194
gtcacggagc gcttaagagg agggtcgggc tcggccgggg agtcccagtg gcggaggcta       60

cgaaacttgg gggagtgcac agaagaactt cgggagcgca cgcgggacca gggaccaggc      120

tgagactcgg ggcgccagtc cgggcagggg cagcgggagc cggccggaga tgccctgtat      180

ccaagcccaa tatgggacac cagcaccgag tccgggaccc cgtgaccacc tggcaagcga      240

ccccctgacc cctgagttca tcaagcccac catggacctg gccagccccg aggcagcccc      300

cgctgccccc actgccctgc ccagcttcag caccttcatg gacggctaca caggagagtt      360

tgacaccttc ctctaccagc tgccaggaac agtccagcca tgctcctcag cctcctcctc      420

ggcctcctcc acatcctcgt cctcagccac ctcccctgcc tctgcctcct tcaagttcga      480

ggacttccag gtgtacggct gctaccccgg ccccctgagc ggcccagtgg atgaggccct      540

gtcctccagt ggctctgact actatggcag cccctgctcg gccccgtcgc cctccacgcc      600

cagcttccag ccgccccagc tctctccctg ggatggctcc ttcggccact tctcgcccag      660

ccagacttac gaaggcctgc gggcatggac agagcagctg cccaaagcct ctgggccccc      720

acagcctcca gccttctttt ccttcagtcc tcccaccggc cccagcccca gcctggccca      780

gagccccctg aagttgttcc cctcacaggc cacccaccag ctgggggagg gagagagcta      840

ttccatgcct acggccttcc caggtttggc acccacttct ccacaccttg agggctcggg      900

gatactggat acacccgtga cctcaaccaa ggcccggagc ggggccccag gtggaagtga      960

aggccgctgt gctgtgtgtg gggacaacgc ttcatgccag cattatggtg tccgcacatg     1020

tgagggctgc aagggcttct tcaagcgcac agtgcagaaa aacgccaagt acatctgcct     1080

ggctaacaag gactgccctg tggacaagag gcggcgaaac cgctgccagt tctgccgctt     1140

ccagaagtgc ctggcggtgg gcatggtgaa ggaagttgtc cgaacagaca gcctgaaggg     1200

gcggcggggc cggctacctt caaaacccaa gcagccccca gatgcctccc ctgccaatct     1260

cctcacttcc ctggtccgtg cacacctgga ctcagggccc agcactgcca aactggacta     1320

ctccaagttc caggagctgg tgctgcccca ctttgggaag gaagatgctg gggatgtaca     1380

gcagttctac gacctgctct ccggttctct ggaggtcatc cgcaagtggg cggagaagat     1440

ccctggcttt gctgagctgt caccggctga ccaggacctg ttgctggagt cggccttcct     1500

ggagctcttc atcctccgcc tggcgtacag gtctaagcca ggcgagggca agctcatctt     1560

ctgctcaggc ctggtgctac accggctgca gtgtgcccgt ggcttcgggg actggattga     1620

cagtatcctg gccttctcaa ggtccctgca cagcttgctt gtcgatgtcc ctgccttcgc     1680

ctgcctctct gcccttgtcc tcatcaccga ccggcatggg ctgcaggagc cgcggcgggt     1740

ggaggagctg cagaaccgca tcgccagctg cctgaaggag cacgtggcag ctgtggcggg     1800

cgagccccag ccagccagct gcctgtcacg tctgttgggc aaactgcccg agctgcggac     1860

cctgtgcacc cagggcctgc agcgcatctt ctacctcaag ctggaggact tggtgccccc     1920

tccacccatc attgacaaga tcttcatgga cacgctgccc ttctgacccc tgcctgggaa     1980

cacgtgtgca catgcgcact ctcatatgcc accccatgtg cctttagtcc acggaccccc     2040

agagcacccc caagcctggg cttgagctgc agaatgactc caccttctca cctgctccag     2100

gaggtttgca gggagctcaa gcccttgggg agggggatgc cttcatgggg gtgaccccac     2160

gatttgtctt atccccccca gcctggcccc ggcctttatg ttttttgtaa gataaaccgt     2220

ttttaacaca tagcgccgtg ctgtaaataa gcccagtgct gctgtaaata caggaagaaa     2280

gagcttgagg tgggagcggg gctgggagga agggatgggc cccgccttcc tgggcagcct     2340

ttccagcctc ctgctggctc tctcttccta ccctccttcc acatgtacat aaactgtcac     2400

tctaggaaga agacaaatga cagattctga catttatatt tgtgtatttt cctggattta     2460

tagtatgtga cttttctgat taatatattt aatatattga ataaaaaata gacatgtagt     2520

tggaactgaa aaaaaaaaaa aa                                              2542


<210>  195
<211>  2468
<212>  DNA
<213>  homo sapiens

<400>  195
gcgttacagg ccctttggcg cctgcgtatt cgtgaagtgt gaaaaaagcg cgcctctgtt       60

gggacgggaa atcagccttt ctattggtca gggttagaaa ccccgccttt gaggcatttt      120

caaccaatgg aagcgcggca ttcttcattt aaactgtcta taaatttctg cctagtcaaa      180

gttaagagtg gcgccaggga tttgaaccgc gctgacgaag tttggtgatc catcttccga      240

gtatcgccgg gatttcgaat cgcgatgatc atcccctctc tagaggagct ggactccctc      300

aagtacagtg acctgcagaa cttagccaag agtctgggtc tccgggccaa cctgagggca      360

accaagttgt taaaagcctt gaaaggctac attaaacatg aggcaagaaa aggaaatgag      420

aatcaggatg aaagtcaaac ttctgcatcc tcttgtgatg agactgagat acagatcagc      480

aaccaggaag aagctgagag acagccactt ggccatgtca ccaaaacaag gagaaggtgc      540

aagactgtcc gtgtggaccc tgactcacag cagaatcatt cagagataaa aataagtaat      600

cccactgaat tccagaatca tgaaaagcag gaaagccagg atctcagagc tactgcaaaa      660

gttccttctc caccagacga gcaccaagaa gctgagaatg ctgtttcctc aggtaacaga      720

gattcaaagg taccttcaga aggaaagaaa tctctctaca cagatgagtc atccaaacct      780

ggaaaaaata aaagaactgc aatcactact ccaaacttta agaagcttca tgaagctcat      840

tttaaggaaa tggagtccat tgatcaatat attgagagaa aaaagaaaca ttttgaagaa      900

cacaattcca tgaatgaact gaagcagccc atcaataagg gaggggtcag gactccagta      960

cctccaagag gaagactctc tgtggcttct actcccatca gccaacgacg ctcgcaaggc     1020

cggtcttgtg gccctgcaag tcagagtacc ttgggtctga aggggtcact caagcgctct     1080

gctatctctg cagctaaaac gggtgtcagg ttttcagctg ctactaaaga taatgagcat     1140

aagcgttcac tgaccaagac tccagccaga aagtctgcac atgtgaccgt gtctgggggc     1200

accccaaaag gcgaggctgt gcttgggaca cacaaattaa agaccatcac ggggaattct     1260

gctgctgtta ttaccccatt caagttgaca actgaggcaa cgcagactcc agtctccaat     1320

aagaaaccag tgtttgatct taaagcaagt ttgtctcgtc ccctcaacta tgaaccacac     1380

aaaggaaagc taaaaccatg ggggcaatct aaagaaaata attatctaaa tcaacatgtc     1440

aacagaatta acttctacaa gaaaacttac aaacaacccc atctccagac aaaggaagag     1500

caacggaaga aacgcgagca agaacgaaag gagaagaaag caaaggtttt gggaatgcga     1560

aggggcctca ttttggctga agattaataa ttttttaaca tcttgtaaat attcctgtat     1620

tctcaacttt tttccttttg taaatttttt ttttttgctg tcatccccac tttagtcacg     1680

agatcttttt ctgctaactg ttcatagtct gtgtagtgtc catgggttct tcatgtgcta     1740

tgatctctga aaagacgtta tcaccttaaa gctcaaattc tttgggatgg tttttactta     1800

agtccattaa caattcaggt ttctaacgag acccatccta aaattctgtt tctagatttt     1860

taatgtcaag ttcccaagtt ccccctgctg gttctaatat taacagaact gcagtcttct     1920

gctagccaat agcatttacc tgatggcagc tagttatgca agcttcagga gaatttgaac     1980

aataacaaga atagggtaag ctgggataga aaggccacct cttcactctc tatagaatat     2040

agtaaccttt atgaaacggg gccatatagt ttggttatga catcaatatt ttacctaggt     2100

gaaattgttt aggcttatgt accttcgttc aaatatcctc atgtaattgc catctgtcac     2160

tcactatatt cacaaaaata aaactctaca actcattcta acattgctta cttaaaagct     2220

acatagccct atcgaaatgc gaggattaat gctttaatgc ttttagagac agggtctcac     2280

tgtgttgccc aggctggtct caaactccac caaatgtact tcttattcat tttatggaaa     2340

agactaggct ttgcttagta tcatgtccat gtttccttca cctcagtgga gcttctgagt     2400

tttatactgc tcaagatcgt cataaataaa attttttctc attgtcatag aaaaaaaaaa     2460

aaaaaaaa                                                              2468


<210>  196
<211>  4600
<212>  DNA
<213>  homo sapiens

<400>  196
ggctagaaga cagcagggga actcgagaag ttggttgttt tcagcagatt aaaacaatac       60

agatttatca gcaagactgt tgaacgcata actgcccaag atgcctgtcc ctccccctcc      120

agcacccccg ccgcccccga cgtttgcact ggccaataca gagaagccta ccttgaataa      180

gacagagcag gctgggagaa atgctctcct ttctgatatc agcaaaggga agaaactaaa      240

gaagacggtc accaatgaca gaagtgcacc aatactggac aaacctaaag gagctggtgc      300

tggaggcggt ggtggtggct ttggtggagg cggcggattt ggcggaggag gtggtggcgg      360

aggcggtgga agttttggag ggggcggacc tccaggtctg ggaggattgt tccaggctgg      420

aatgccgaag ctgagatcca cggccaacag ggataatgat tctggaggaa gccgaccacc      480

attgttgcca ccgggaggaa gatccacatc tgcgaaaccc ttttcacccc caagtggccc      540

agggaggttt cctgtgcctt ctccaggcca cagaagtggt cccccagagc ctcagaggaa      600

ccgaatgccg cccccaaggc ccgacgtggg ctcaaagcct gatagcattc ctcctccagt      660

acctagtact ccaagaccca ttcaatcaag tccgcacaac cgggggtccc caccagtgcc      720

cggaggcccc aggcagccca gccccgggcc cactcctccc cctttccctg gaaaccgcgg      780

cactgctttg ggaggaggct caatacgtca gtcccccttg agctcctcct cgcccttctc      840

caaccggcct cccctgccgc ctacccccag cagggccttg gatgacaaac cccctccacc      900

acctcctcca gtgggcaaca ggccctccat ccacagggaa gcggttcccc ctcctcctcc      960

tcagaacaac aagcctccag tgccttccac tccgcggcct tcggcctcct cacaggcccc     1020

acctccgccg ccacctccca gcaggcccgg gccgcctcct ctgcctccaa gttccagcgg     1080

caatgacgaa accccaagac tcccacagcg gaatctgtcc ctcagttcgt ccacgccccc     1140

gttaccttcg ccaggacgtt caggtcctct tcctcccccg cccagtgaga gacccccacc     1200

tccagtgagg gacccgccag gccgatcagg ccccctccca ccacctcctc cagtaagcag     1260

aaacggcagc acatctcggg ccctgcctgc tacccctcag ttgccatcca ggagtggagt     1320

agacagtccc aggagtggac ccaggcctcc ccttcctcct gataggccca gtgctggggc     1380

acctccccca cctccaccat caacatctat tagaaatggc ttccaagact ctccatgtga     1440

agatgagtgg gaaagcagat tctacttcca tccgatttcc gatttgccac ctccagagcc     1500

atatgtacaa acgaccaaaa gttatcccag caaactggca agaaacgaaa gccggagtgg     1560

atccaaccga agagaaaggg gtgctccacc actccctccc atcccgaggt gatctttgcc     1620

tgctcttctc tacccaagct caagagctgc ttctgttgct atctaagaac tgcataccct     1680

cctccctgct tcttcccttg tgcctcatgt atgggcagga ggaaaggtgg gagggggagt     1740

gggaatatgc gtgtgtgggt gggaatcggt aagaaatgca cctagctttt catattgtgt     1800

ttattctcca ggctattgct tgcttcagct gcagcctgcc tgtgctggct gctggggtcg     1860

ataggctttt gtcgtaatag gcagagatga cttgcatccc agctttccac caaccaaatt     1920

caaacattca ctgcttattt gttacagact gtaattatta aagtccctga gagctgtttt     1980

ctcccgttcc tttttcgcat gcttggcctc ctctctgttt ctatgaacca cagaccacct     2040

aagcaagctg ctgagtaagg gctcactgga aacttgcagt cacaggatgt ccaatctttg     2100

gcagtccgag cttggctcta ggacagagct gtccaataga aatataatgt gagccccata     2160

tacaattttt acatttctaa tatattttaa acaagtgaag ttaatatgca tccaaaatat     2220

ttcaacctgt aatcaacata aaattttaat gagatatttt atattatttt ttggtactga     2280

atcttcaaaa tccagagtgt attttacact taccgcacat ctccattcag actagtcaca     2340

tttttaagtg ctcagtagcc acatgtggct ggtggctact ggattagaca gcacgagtct     2400

ggaagatgga agctagtgca gaaacctctt gtttaaaaaa caaaaaaggc aagatgggct     2460

tgagcgattc aagaggcaac taaaaataaa attaggaccc agcaccttgt ttgacacaca     2520

gtttgacctt cgattttcct cccttaactt ccctcttccc ttaatatctg tatacaagtg     2580

ttgcttcaaa gtaccaaggt cagaaattga ttcagtacgg tttactaaag tcatgtggaa     2640

taaagccatt ggaaacaaat ggaaagcctg tcgggacttc tgggctcaga accagctggc     2700

tcacgcactc cacttgtcag ctggacttct gccttgtgaa atggaagcag cctttgttcc     2760

tttctggctg agcaagctcc tgaggctggg agagactagg aaggcttggt aggaggggaa     2820

aaaagtcagg aaaagatatc aaatcagaaa catggaagaa gaagggaacc gatttgagtt     2880

ggtgggcaaa actctaaaaa tctaaatctg atgcttatgt aagggttgag cgaattaggg     2940

agattgctag tggaaattgg agggaatttg ttttgcatca tttgtctagg atctatgcaa     3000

atatagctcc actaaaggac catagggaag agccagcctt gccttttctt atatgatttt     3060

gtttacaaaa ttttactggg acttttaaat ctagctatag agttgggaaa aaatatttcc     3120

acttagatat tttacatggt tttgtttaaa attaccatta cttgtttttt aaaaacacat     3180

gaccacatat gtatatgtat atctacctaa acattgtatc atggtttcag tatgttattc     3240

atgtattact gggagatgct accaagaaac caacccaaag aaaattctga aaaatacatt     3300

tctatttata gaataaatgt ttcatttata taaaagcaaa agaacttaga gttctaataa     3360

atgggatgtc taataaatta tgaagttact gatttgaata tattatattt ttataacttc     3420

cttgccaaag tcctgattta gtacattaga gaacctgtgt ttcctctctc ctctaccatt     3480

catctctctt ccatacagtc atttgggctt tttactcaaa gagaatcaag aaataataag     3540

gtataacaag cttggcaaag tgttggcttt ttaaaaaaaa atttttttaa tctctagcag     3600

tttggtaatt tagcagcatc atttatttgg gattctttta tctgatttca acagtgaaaa     3660

acatccctat gataaagcct aatgacccat ttcacaaaag atggaatttg cccttcctag     3720

aaaatatgac ggagaaaagt ctgactcaga gaaagtgagt ctgaatttta taaggggtag     3780

taagaattgg acaattcctt tgcatatctg aacttggcag gtaccgttct aaatctgaaa     3840

cagggtgata gctcaaagtt gccattcatc cagaatagat tgttttagaa tgtagtgttt     3900

aagtgactgt ttcattaata cacctacacc ctttctttga aagtttgcaa cctaattgca     3960

tctaaaacta tgaataagtt ctgtggtaaa atcttaaact atggaaaatt acaaaaatga     4020

atttttcttc cctgaaatca gagcttacat gtgtgttttt ttataacatt ttcagataaa     4080

tgtattcaac atgtaataca gtattttaac attcacctct tattttatat tgaaatgtat     4140

tacagtatta aaactcagtg ttcagtattt atttcactat gcattttatt tagtaaaagc     4200

caggagaaat gtttaatcca atggtgcctt actttgtgat ttaaaagaaa tcaacttttt     4260

tttatgtcta agtagtagat tatttgcata tttgtaaaaa ctgttaggtc tttatatttt     4320

aaagtgtaat accagttttg ttattttagt agcagaaatg ggatgattgt taaagttccc     4380

caaaaatgtt ggcatgaaat taatttttcc ctccttatag tcaaggaccg tagaggaaga     4440

aaaacttttt tttcatacca tgcactatgt aaacagacac attttgctat ctgtgtcatc     4500

aggatagtgt aagtggtagg gtagagacta ccctagacat ctgcatcttt gtaagttagc     4560

cagacaataa agaaaagcag aatgaaaaaa aaaaaaaaaa                           4600


<210>  197
<211>  2384
<212>  DNA
<213>  homo sapiens

<400>  197
gcggccgcca ccccaccatg ctcaagcgct gcggccggcg cctgctgctg gcgctggcgg       60

gcgcgctgct cgcctgcctg ctggtgctca ccgccgaccc gccgccgcct ccactgcccg      120

ccgagcgcgg ccggcgcgcg ctgcgcagcc tggcgggccc cgcgggggct gccccggcgc      180

ccgggctggg ggcggcggcg gcggcgcccg gggcgctggt ccgcgacgtg cacagtctgt      240

ccgagtactt cagcctgctc acccgcgcgc gcagagatgc gggcccgccg cccggggctg      300

ccccccgccc cgccgacggc cacccgcgcc ccctggccga gccgctcgcg ccccgagacg      360

tcttcatcgc tgtcaagacc accaaaaagt tccaccgcgc gcgcctcgac ctgctgctgg      420

agacctggat ctcgcgccac aaggagatga cgttcatctt cactgacggg gaagatgagg      480

ccctggccag gcacacgggc aacgtggtca tcacaaactg ctcggccgcc cacagccgcc      540

aggcgctgtc ctgcaagatg gccgtggagt atgaccgctt catcgagtcc ggcaggaagt      600

ggttctgcca cgtggacgat gacaactacg tcaacctgcg ggccctgctg cggctgctgg      660

ccagctaccc gcacacgcgg gacgtctacg tcggcaagcc cagcctggac aggcccatcc      720

aggccatgga gcgggtcagc gagaacaagg tgcgtcctgt ccacttctgg tttgccacgg      780

gcggcgctgg cttctgcatc agccgtgggc tggctctgaa gatgagcccg tgggccagcg      840

ggggtcactt catgaatacg gctgagcgga tccggctgcc tgatgactgc accatcggct      900

acatcgtgga ggccctgctg ggtgtgcccc tcatccgcag cggcctcttc cactcccacc      960

tggagaacct gcagcaggtg cccacctcgg agctccacga gcaggtgacg ctgagctacg     1020

gtatgtttga aaacaagcgg aacgccgtcc acgtgaaggg gcccttctcg gtggaggccg     1080

acccatccag gttccgctcc atccactgcc acctgtaccc ggacacaccc tggtgtcccc     1140

gcactgccat cttctagtgg ccatggctga gacccaatcc ctgggcgccc ctggtatcca     1200

aagggcccag ggaccctgtt gcgctgccct ggcctcggca ttcgaggctc ccctagggcc     1260

gtgcctgtgc gtgtgcgtgt gcgtgtgtgt gtgtgtgtac tgcatgccca cccgggtagc     1320

aggctgctgg gcagttctgc tctgtggagg ggcgggcacc agcgccactt atgtgcctct     1380

gctccgaggg ccagtgggct gcagggcctg cttggaggaa ggatttgtgt gtcggaggcc     1440

actccgaggg caattctgtt aggatttttg gatctttcta cagctacggg gctccgggct     1500

actttgcagg gatgcgatgc gtaggtgcct ttctcttcct gctgaccaca agctctgtgc     1560

tgggggtacc tgtgccctga agtcctggcc cctgtgtcat agccccaagt acgactcact     1620

gagccatgct cattgcaggg gaggctgggt ctgggggtgc gtgacccaat ccccttcctc     1680

ctggcctgga cgctgtggct taagagtaac agcagccacc gcccagttcc agtggcccca     1740

cgaagccccc agtggctggc tgtccagctg ggcaaacagt ggcacccctc ccagctcttc     1800

tgagtgggga gtcttccagg cctcctcaga ggtcttccct ttgcctcccc aggacagggt     1860

gagtcagagc tcagcattta atctcctctc caaagtagag agcaagtcgc ccacagtggg     1920

cgtgtctgta aatattgtga cagtattttt ttactgtgct gttttttttg aaaggggatg     1980

ggtaaaaagt agggtgttct tgttttttgc ttgggagggt gggggtgggg gagggtctta     2040

ttttatctta tcttttctgt ggatcagaaa aaacagaagc caaactcggg gtcatctttg     2100

tttttaaagc tgaagtggga ctgtctggca ctctgtgtat ttatgcgttc cagcatctgg     2160

aacctcccat ccctgccctc ctcctgtgta gctgccacct ccccgctggg cccagcatgg     2220

ctcacctgtc ccgtgggctg tgtttcttgt tgtttttctc tttgcaaaga catagctagg     2280

aaagcgaatg ataagggaaa agttctcagg gaattgaagt gttgttgcta tggtgacgtc     2340

cttttgctgt gaataaaggt gctctttgca gcaaaaaaaa aaaa                      2384


<210>  198
<211>  8320
<212>  DNA
<213>  homo sapiens

<400>  198
gtgtgtggat gtgtgagtga gagggaacga gagtaagaga aagaaagaag tgaggggatg       60

taaactcgaa taaatttcaa agtgcctccg agggatgcaa cgggcaaaaa ctgaactgtt      120

caggcttcag attgtaactg acgatctgag gaaaaatgag gtgctcgatg aattttcgtt      180

tgtatttttt ggcgaggcgg gggaggtgtt gagatttttt ttttttcccc tcggggtggg      240

tgcgaggggg atgcatccta gcctgcccga cccggagcaa gtcgcgtctc cccgccggag      300

cccccccacc catttctttg ctgaacttgc aattccgtgc gcctcggcgt gtttccccct      360

ccccccttcc ctccgtcccc tcccctcccc ggagaagaga gttggtgtta agagtcaggg      420

atcttggctg tgtgtctgcg gatctgtagt ggcggcggcg gcggcggcgg cggggaggca      480

gcaggcgcgg gagcgggcgc aggagcaggc ggcggcggtg gcggcggcgg ttagacatga      540

acgccgcctc ggcgccggcg gtgcacggag agccccttct cgcgcgcggg cggtttgtgt      600

gattttgcta aaatgcatca ccaacagcga atggctgcct tagggacgga caaagagctg      660

agtgatttac tggatttcag tgcgatgttt tcacctcctg tgagcagtgg gaaaaatgga      720

ccaacttctt tggcaagtgg acattttact ggctcaaatg tagaagacag aagtagctca      780

gggtcctggg ggaatggagg acatccaagc ccgtccagga actatggaga tgggactccc      840

tatgaccaca tgaccagcag ggaccttggg tcacatgaca atctctctcc accttttgtc      900

aattccagaa tacaaagtaa aacagaaagg ggctcatact catcttatgg gagagaatca      960

aacttacagg gttgccacca gcagagtctc cttggaggtg acatggatat gggcaaccca     1020

ggaacccttt cgcccaccaa acctggttcc cagtactatc agtattctag caataatccc     1080

cgaaggaggc ctcttcacag tagtgccatg gaggtacaga caaagaaagt tcgaaaagtt     1140

cctccaggtt tgccatcttc agtctatgct ccatcagcaa gcactgccga ctacaatagg     1200

gactcgccag gctatccttc ctccaaacca gcaaccagca ctttccctag ctccttcttc     1260

atgcaagatg gccatcacag cagtgaccct tggagctcct ccagtgggat gaatcagcct     1320

ggctatgcag gaatgttggg caactcttct catattccac agtccagcag ctactgtagc     1380

ctgcatccac atgaacgttt gagctatcca tcacactcct cagcagacat caattccagt     1440

cttcctccga tgtccacttt ccatcgtagt ggtacaaacc attacagcac ctcttcctgt     1500

acgcctcctg ccaacgggac agacagtata atggcaaata gaggaagcgg ggcagccggc     1560

agctcccaga ctggagatgc tctggggaaa gcacttgctt cgatctattc tccagatcac     1620

actaacaaca gcttttcatc aaacccttca actcctgttg gctctcctcc atctctctca     1680

gcaggcacag ctgtttggtc tagaaatgga ggacaggcct catcgtctcc taattatgaa     1740

ggacccttac actctttgca aagccgaatt gaagatcgtt tagaaagact ggatgatgct     1800

attcatgttc tccggaacca tgcagtgggc ccatccacag ctatgcctgg tggtcatggg     1860

gacatgcatg gaatcattgg accttctcat aatggagcca tgggtggtct gggctcaggg     1920

tatggaaccg gccttctttc agccaacaga cattcactca tggtggggac ccatcgtgaa     1980

gatggcgtgg ccctgagagg cagccattct cttctgccaa accaggttcc ggttccacag     2040

cttcctgtcc agtctgcgac ttcccctgac ctgaacccac cccaggaccc ttacagaggc     2100

atgccaccag gactacaggg gcagagtgtc tcctctggca gctctgagat caaatccgat     2160

gacgagggtg atgagaacct gcaagacacg aaatcttcgg aggacaagaa attagatgac     2220

gacaagaagg atatcaaatc aattactagc aataatgacg atgaggacct gacaccagag     2280

cagaaggcag agcgtgagaa ggagcggagg atggccaaca atgcccgaga gcgtctgcgg     2340

gtccgtgaca tcaacgaggc tttcaaagag ctcggccgca tggtgcagct ccacctcaag     2400

agtgacaagc cccagaccaa gctcctgatc ctccaccagg cggtggccgt catcctcagt     2460

ctggagcagc aagtccgaga aaggaatctg aatccgaaag ctgcgtgtct gaaaagaagg     2520

gaggaagaga aggtgtcctc agagcctccc cctctctcct tggccggccc acaccctgga     2580

atgggagacg catcgaatca catgggacag atgtaaaagg gtccaagttg ccacattgct     2640

tcattaaaac aagagaccac ttccttaaca gctgtattat cttaaaccca cataaacact     2700

tctccttaac ccccattttt gtaatataag acaagtctga gtagttatga atcgcagacg     2760

caagaggttt cagcattccc aattatcaaa aaacagaaaa acaaaaaaaa gaaagaaaaa     2820

agtgcaactt gagggacgac tttctttaac atatcattca gaatgtgcaa agcagtatgt     2880

acaggctgag acacagccca gagactgaac ggcaatcttt ccacactgtg gaacaatgca     2940

tttgtgccta aacttctttt ggaaaaaaaa aatataatta atttgtaagt ctgaaaaaaa     3000

aatatttaat ttaaaaaaaa ttgtaaactt gcaataatga aaaagtgtac ttctgaagaa     3060

aactacatga acgtttttgt tggtattcaa gtcagctagt gtttataatt actggatatt     3120

gaattagggg aagctcggct gccctagtaa caaaaccagc aaacgtcctg atgacaacga     3180

agtgatgaca ttagccattc cttagggtag gaggaacaga tggatcttat agacctatga     3240

caaatatata tataaatata tatataaata tatattaaaa atttagtgac tatggtaagc     3300

ttttgttcat ttgtttcaga cttttttctc ctgtaaaaaa atagtactga ttaacttttt     3360

taaaagaaag attttactgt aaatatggat tttttttttt ttggtcttat ttctgtccct     3420

ttccctggtt tgttatcgta acctgtagtg ccaactctgc ttccagaggg gtagtgcagg     3480

atgaaatgct gaccctgatg ttgcttctca ttcataaata agtagaaagt tgtttctcca     3540

gtcttttggg aacacaggac ttaaaagtca catcatgtgt agatattaca agcagcatta     3600

ccaagacatg gcaaaaagag tttgtctgaa ttgtaatgtt gcgtttgtga acctattctg     3660

ggattttcag aggtacaagg ttagaatgct acaatgttac cactgtgcct tccaatgttt     3720

atatcatcgg aaacataaca taatcaaagt ggctgtgatt taacaaaatg attaaagtgt     3780

tacctacctg tgtagccgaa gtagtgtgca gtgaggcgtt tctgaataca tggtcagatt     3840

tttggaaaaa aacaaaaaca aaaaaaacaa gtaaagttca aaaaccgtca aatgagaaaa     3900

ttgcaagtag tgtgacagag ctgattgatt ttgttgcttt cttgattttt tttttcaaaa     3960

tgggtttact aaaatgtaga tgacttaact gcctcctcct tcgtctgaaa aatgccaata     4020

ttcaatcatc atgcagcatt ataacaagcc ttataagtcc taaagcatta agttgcactt     4080

ttttgaggag gggtagtgca gtatttctct ggccagtatg aatgaagttt atacttacca     4140

tatttgatag aaacatagat caagctatgg cacagcgact catcagatag ctagctttga     4200

cgtctgggca caattgaacc aacttccatc gtgaatcttt ataatgattg actttggtgt     4260

atagtgcagt aaacaaatag tgctcctagt taagtatttg tcagcatcct tttgtctcta     4320

acttgtttct atttttacag ccacacaatt cttggcatgt attaagaaaa aaaaaaatcc     4380

ctgttcaagt agtttttcca cctatcagca ctgagtaaat gccataaatc cattgaaatg     4440

gtctaaatgt tccatctgtt ctcctgtttt gccagttata tagtaatgaa atacatttgt     4500

aaattttatg caacaaatgg caaacgtatc attattttga aattgtgtat gtaaaagtta     4560

tatttttaca tgtagactct tgttattatg tgttttaata cattgtatca gtttttgttt     4620

ttttttaaaa actgtggttt aaaaagaagt ctcatttaaa tgaaatagct acaagaatca     4680

gaattttatg ttcatttctg aaaatgtaag aacaaataag atagttacca cgtggtcatc     4740

ttttacaaac ccataaacat tttgattagc tgtgtgtgtg ttgaaaaact gtaaatatgt     4800

tcagtagcga taaaactaaa ataactttga tttgttgata agttcctaaa atgtggaggt     4860

ggattaaaac cttaggagaa tagcagaaat caaacttcat gaaaagttat tttggggctt     4920

tcctgtgaaa tgtatgaaca aagaggctca gagaaggaca tggaagacaa taatgtatac     4980

tctctcctcc tccctgaata atgaaaacca tgtgtatttg ttccctccgt atgttaaaga     5040

tttcctttta gtggtacatt ctgcactcat tttgtatagt ctaccaaggc gggtatccct     5100

aggaacaata ttatatagga agcaggtata ctctgatcac attcaggata agtgtacaga     5160

agaaaatacg gtgtttactc tttagggaac tggaaacact ccctgcattg atgtacattt     5220

taagaatggc acttttgata catgttatca taaaggtgct taatagagct gaattaaagt     5280

ttttcaaatc tgtaaacaaa gcaaaaaagt aaattgtagt catttgatta ttttttaaat     5340

tggtgcttta tattttgttc tcactcagag taaaagctgc aatttattgt tcaccagctt     5400

tgatgtattc attactcagt aatgcaatac ctctattgtt gaattccctt tggaaataag     5460

tgaaaattct aacggccact gaaagctgct cgctaggttt tgcttggtgg agaaacataa     5520

tctgcaccta tccatattaa ttgggttgta tccccattaa aaaagaaaaa aagggaatgt     5580

ggccttttta gtgtgttttt tattgttgtt gttttgtaat tatcaaaccc aggtaagata     5640

ttggtatcct gcactggatt ttcaaatgaa gttcagcaga agacagttaa gattaaagta     5700

ctatacaaaa atttcaaaag ggtccatact acgctatctg tatgacgaca cttaggctgg     5760

ggatctcttt cagaaactcg gactttaaaa gcaacttgga gcagttgatc cacctccaca     5820

ttcaagtaat ttatgaatat gcagaatagg gatctgttca tctagaaatt tttaccattt     5880

gtcttctgtg tagctgcaag gaacactaat gtttatacaa ctgtcagtcc acccagtggt     5940

gcaactggtt ctgattcagt cttccgattc ctttttattt ttcacttttt cctatttctg     6000

aatttttttt tttatttgtg atcttgattt tgatgagggg ttggggagtg gggagggagt     6060

cgaaccaaga cttggagtta agaggatttt catcttttgc atccaacagg cagaatatga     6120

tctgtgtcca aaagtgaact tgagtcagga atgaatcaat ttcagcataa acaagcacaa     6180

aaatttagtc tgctggctga ctggaagcaa aaaagtcaag atggaatatg atgaattcca     6240

acacaatggg gcaccaaggc ctttaggcct ctctttttat tttgctttgg ttttgtttgt     6300

ttttctttag agacatgctc tttctcatgg gacttgaagt ggactcatct ttgtgcagtg     6360

ctggttttgc catactcatt tcaagtatta tagacatatg taatggtgaa aatatatgaa     6420

ctgtggcctt tttcattctt gttacttgtg atgcaattaa gtgaagataa gaaaaaaaaa     6480

aaaaaagcag agatttacca tgtatcagtg cctggctttt tgttataaag ctttgtttgt     6540

ctagtgctct tttgctataa aatagactgt agtacaccct agtaggaaaa aaaaaaaact     6600

aaatttaaaa ataaaaaata tatttggctt atttttcgca ggagcaatcc ttttatacca     6660

tgaatattac aaaaaaattg tcagattctg aatatttctt ctttgtagat ttttggaatc     6720

attatgagta aaagtttgtt actttatttt actatttaaa agatgttatt ttaccatgtg     6780

ttaccaagat gaaactgtat gggtagcttt tttgtttgtt ttttgttttg tttttgtttt     6840

tgtttttgtt tttagttgta ggtcgcagcg gggaaatttt ttgcgactgt acacatagct     6900

gcagcattaa aaacttaaaa aaattgttaa aaaaaaaaaa agggaaaaca tttcaaaaaa     6960

aaaaaaaaag ataaacagtt acaccttgtt ttcaatgtgt ggctgagtgc ctcgattttt     7020

tcatgttttt ggtgtatttc tgatttgtag aagtgtccaa acaggttgtg tgctggagtt     7080

ccttcaagac aaaaacaaac ccagcttggt caaggccatt acctgtttcc catctgtagt     7140

tattcgatga agtcatgtac atgaccgttc tgtagcaata aatgtgccat ttttataaac     7200

tgtttctgac acttgtttca tttcattttg cattgtccat atagctatga ttctcttctg     7260

taagtaaaac gcatctatat ttcattttcc aagtgttgga ggtattgaca gcttaacaaa     7320

caaaacatac aaaaaaaatc acaaaaacaa attgaaaagc aaagcacatg attgatcaag     7380

gaagagatgc ccttaatgaa aatggaacgg gatgcatgca aaacaaaaag aaaactgtct     7440

agaggattaa ctaattgaag gaatataatt aatgtgtgtg taacactgaa gctatgcatt     7500

tgaagagctc tgaactgcac cagtgttttc ggttgtgctg caggttgcta agtcaagtca     7560

gccttaacct tttgcaccag ttggtcggct gtttggcaga acattctcag atcttttcag     7620

tcaaaaatct aagatgattt attttgtatc actttgttaa aagctgaata ttgttaacta     7680

cagttaatat taacactgta tttatacttt ctcaaactac atccgcccca ccacttctgg     7740

ttgcctctgt tgactattaa tccagatgta aacaaccaga tgtttttttc taacttgtac     7800

aaactgacgt gtgtcaacta tcatggaagg aaaaaaatgt acagattaaa attattcagt     7860

gttatgtact gtaagttaat atttttgtag aatggacatc aatctacttt gcaaaatttg     7920

gaggctattt caacattgca ctgtagaaat gtaaagtaat gtatgcaatg taaaggaaag     7980

cccgcggtag ctgagcgctt cataacagaa tgttctaatc aagtacgtgg tatttgggga     8040

tgtctccaat attgctcttg tattctttct aattgggttt agtgactagt tgaaggaaaa     8100

tgttataacg ccatttggtt cacatgtgaa gtgccctcca tagccaaatg ttgggatttt     8160

tttttttttc gtttttggtt ggactgtttg cagatattta aattttatga aatttccaaa     8220

gattttggtt gataaccccc ttttaccttc taaatgattt gagatgttct tatgttctta     8280

ctgtgtgttt taaatatata taaaagagcc acaagcattt                           8320


<210>  199
<211>  4811
<212>  DNA
<213>  homo sapiens

<400>  199
ccttgccaag taacagcttt gctgtccaac atcgtgtgct gcttcgcgag aaagtcacat       60

tcggaccctt tggctagatt atcttagacg aattttacaa tgtgaagttc tgcatagatg      120

ccagtcaacc agatgttgga agctggctca agtacattag attcgctggc tgttatgatc      180

agcacaacct tgttgcatgc cagataaatg atcagatatt ctatagagta gttgcagaca      240

ttgcgccggg agaggagctt ctgctgttca tgaagagcga agactatccc catgaaacta      300

tggcgccgga tatccacgaa gaacggcaat atcgctgcga agactgtgac cagctctttg      360

aatctaaggc tgaactagca gatcaccaaa agtttccatg cagtactcct cactcagcat      420

tttcaatggt tgaagaggac tttcagcaaa aactcgaaag cgagaatgat ctccaagaga      480

tacacacgat ccaggagtgt aaggaatgtg accaagtttt tcctgatttg caaagcctgg      540

agaaacacat gctgtcacat actgaagaga gggaatacaa gtgtgatcag tgtcccaagg      600

catttaactg gaagtccaat ttaattcgcc accagatgtc acatgacagt ggaaagcact      660

atgaatgtga aaactgtgcc aagcaggttt tcacggaccc tagcaacctt cagcggcaca      720

ttcgctctca gcatgtcggt gcccgggccc atgcatgccc ggagtgtggc aaaacgtttg      780

ccacttcgtc gggcctcaaa caacacaagc acatccacag cagtgtgaag ccctttatct      840

gtgaggtctg ccataaatcc tatactcagt tttcaaacct ttgccgtcat aagcgcatgc      900

atgctgattg cagaacccaa atcaagtgca aagactgtgg acaaatgttc agcactacgt      960

cttccttaaa taaacacagg aggttttgtg agggcaagaa ccattttgcg gcaggtggat     1020

tttttggcca aggcatttca cttcctggaa ccccagctat ggataaaacg tccatggtta     1080

atatgagtca tgccaacccg ggccttgctg actattttgg cgccaatagg catcctgctg     1140

gtcttacctt tccaacagct cctggatttt cttttagctt ccctggtctg tttccttccg     1200

gcttgtacca caggcctcct ttgatacctg ctagttctcc tgttaaagga ctatcaagta     1260

ctgaacagac aaacaaaagt caaagtcccc tcatgacaca tcctcagata ctgccagcta     1320

cacaggatat tttgaaggca ctatctaaac acccatctgt aggggacaat aagccagtgg     1380

agctccagcc cgagaggtcc tctgaagaga ggccctttga gaaaatcagt gaccagtcag     1440

agagtagtga ccttgatgat gtcagtacac caagtggcag tgacctggaa acaacctcgg     1500

gctctgatct ggaaagtgac attgaaagtg ataaagagaa atttaaagaa aatggtaaaa     1560

tgttcaaaga caaagtaagc cctcttcaga atctggcttc aataaataat aagaaagaat     1620

acagcaatca ttccattttc tcaccatctt tagaggagca gactgcggtg tcaggagctg     1680

tgaatgattc tataaaggct attgcttcta ttgctgaaaa atactttggt tcaacaggac     1740

tggtggggct gcaagacaaa aaagttggag ctttacctta cccttccatg tttcccctcc     1800

cattttttcc agcattctct caatcaatgt acccatttcc tgatagagac ttgagatcgt     1860

tacctttgaa aatggaaccc caatcaccag gtgaagtaaa gaaactgcag aagggcagct     1920

ctgagtcccc ctttgatctc accactaagc gaaaggatga gaagcccttg actccagtcc     1980

cctccaagcc tccagtgaca cctgccacaa gccaagacca gcccctggat ctaagtatgg     2040

gcagtaggag tagagccagt gggacaaagc tgactgagcc tcgaaaaaac cacgtgtttg     2100

ggggaaaaaa aggaagcaac gtcgaatcaa gacctgcttc agatggttcc ttgcagcatg     2160

caagacccac tcctttcttt atggacccta tttacagagt agagaaaaga aaactaactg     2220

acccacttga agctttaaaa gagaaatact tgaggccttc tccaggattc ttgtttcacc     2280

cacaaatgtc agctattgaa aacatggcag aaaagctaga gagcttcagt gccctgaaac     2340

ctgaggccag tgagctctta cagtcagtgc cctctatgtt caacttcagg gcgcctccca     2400

atgccctgcc agagaacctt ctgcggaagg gaaaggagcg ctatacctgc agatactgtg     2460

gcaagatttt tccaaggtct gcaaacctaa cacggcactt gagaacccac acaggagagc     2520

agccttacag atgcaaatac tgtgacagat catttagcat atcttctaac ttgcaaaggc     2580

atgttcgcaa catccacaat aaagagaagc catttaagtg tcacttatgt gataggtgtt     2640

ttggtcaaca aaccaattta gacagacacc taaagaaaca tgagaatggg aacatgtccg     2700

gtacagcaac atcgtcgcct cattctgaac tggaaagtac aggtgcgatt ctggatgaca     2760

aagaagatgc ttacttcaca gaaattcgaa atttcattgg gaacagcaac catggcagcc     2820

aatctcccag gaatgtggag gagagaatga atggcagtca ttttaaagat gaaaaggctt     2880

tggtgaccag tcaaaattca gacttgctgg atgatgaaga agttgaagat gaggtgttgt     2940

tagatgagga ggatgaagac aatgatatta ctggaaaaac aggaaaggaa ccagtgacaa     3000

gtaatttaca tgaaggaaac cctgaggatg actatgaaga aaccagtgcc ctggagatga     3060

gttgcaagac atccccagtg aggtataaag aggaagaata taaaagtgga ctttctgctc     3120

tagatcatat aaggcacttc acagatagcc tcaaaatgag gaaaatggaa gataatcaat     3180

attctgaagc tgagctgtct tcttttagta cttcccatgt gccagaggaa cttaagcagc     3240

cgttacacag aaagtccaaa tcgcaggcat atgctatgat gctgtcactg tctgacaagg     3300

agtccctcca ttctacatcc cacagttctt ccaacgtgtg gcacagtatg gccagggctg     3360

cggcggaatc cagtgctatc cagtccataa gccacgtatg acgttatcaa ggttgaccag     3420

agtgggacca agtccaacag tagcatggct ctttcatata ggactattta caagactgct     3480

gagcagaatg ccttataaac ctgcagggtc actcatctaa agtctagtga ccttaaactg     3540

aatgatttaa aaaagaaaag aaagaaaaaa gaaactattt attctcgata ttttgttttg     3600

cacagcaaag gcagctgctg acttctggaa gatcaatcaa tgcgacttaa agtgattcag     3660

tgaaaacaaa aaacttggtg ggctgaaggc atcttccagt ttaccccacc ttagggtatg     3720

ggtgggtgag aagggcagtt gagatggcag cattgatatg aatgaacact ccatagaaac     3780

tgaattctct tttgtacaag atcacctgac atgattggga acagttgctt ttaattacag     3840

atttaatttt tttcttcgtt aaagttttat gtaatttaac cctttgaaga cagaagtagt     3900

tggatgaaat gcacagtcaa ttattataga aactgataac agggagtact tgttccccct     3960

tttgccttct taagtacatt gtttaaaact agggaaaaag ggtatgtgta tattgtaaac     4020

tatggatgtt aacactcaaa gaggttaagt cagtgaagta acctattcat caccagtacc     4080

gctgtaccac taataaattg tttgccaaat ccttgtaata acatcttaat tttagacaat     4140

catgtcactg tttttaatgt ttattttttt gtgtgtgttg cgtgtatcat gtatttattt     4200

gttggcaaac tattgtttgt tgattaaaat agcactgttc cagtcagcca ctactttatg     4260

acgtctgagg cacacccctt tccgaatttc aaggaccaag gtgacccgac ctgtgtatga     4320

gagtgccaaa tggtgtttgg cttttcttaa cattcctttt tgtttgtttg ttttgttttc     4380

cttcttaatg aactaaatac gaatagatgc aacttagttt ttgtaatact gaaatcgatt     4440

caattgtata aacgattata atttctttca tggaagcatg attcttctga ttaaaaactg     4500

tactccatat tttatgctgg ttgtctgcaa gcttgtgcga tgttatgttc atgttaatcc     4560

tatttgtaaa atgaagtgtt cccaacctta tgttaaaaga gagaagtaaa taacagactg     4620

tattcagtta ttttgccctt tattgaggaa ccagatttgt tttctttttg tttgtaatct     4680

cattttgaaa taatcagcaa gttgaggtac tttcttcaaa tgctttgtac aatataaact     4740

gttatgcctt tcagtgcatt actatgggag gagcaactaa aaaataaaga cttacaaaaa     4800

ggagtatttt t                                                          4811


<210>  200
<211>  657
<212>  DNA
<213>  homo sapiens

<400>  200
gacaactcgg tggtggccac tgcgcagacc agacttcgct cgtactcgtg cgcctcgctt       60

cgcttttcct ccgcaaccat gtctgacaaa cccgatatgg ctgagatcga gaaattcgat      120

aagtcgaaac tgaagaagac agagacgcaa gagaaaaatc cactgccttc caaagaaacg      180

attgaacagg agaagcaagc aggcgaatcg taatgaggcg tgcgccgcca atatgcactg      240

tacattccac aagcattgcc ttcttatttt acttctttta gctgtttaac tttgtaagat      300

gcaaagaggt tggatcaagt ttaaatgact gtgctgcccc tttcacatca aagaactact      360

gacaacgaag gccgcgcctg cctttcccat ctgtctatct atctggctgg cagggaagga      420

aagaacttgc atgttggtga aggaagaagt ggggtggaag aagtggggtg ggacgacagt      480

gaaatctaga gtaaaaccaa gctggcccaa ggtgtcctgc aggctgtaat gcagtttaat      540

cagagtgcca tttttttttt tgttcaaatg attttaatta ttggaatgca caattttttt      600

aatatgcaaa taaaaagttt aaaaacttaa aaaaaaaaaa aaaaaaaaaa aaaaaaa         657


<210>  201
<211>  5352
<212>  DNA
<213>  homo sapiens

<400>  201
tgattgtgcc tctgcacctc ctcaggtgac cgagggctgg gcaggaggac acagactctt       60

tcatgaagca gtgactagta taggaaaaac agagcctctc tgtagagatg cttaaagtgc      120

tagctttatt taaaaatcag ctggcaaagc gggagtgaag aacacacatt ttcagaagat      180

accggtttcc tgttttcatt aagaaaacag ggaatgcgga acagctgagt gcggcggggg      240

tggtgtcact gcagccggag ggagacctcg ccggtgaaag ctcagcctat ggcatccgag      300

cgtggccggc caagtttaca cgaatgttga aacttctcct cacggggtga ggatcgaggg      360

cgcccgaggc cgggtccggc tgagctggag cgagctgtgc ggggcagcgc gggctggcgg      420

ggagcgcggc gggcgccacg tggaaaagca ggtgatattc tcagtggaga ccaggacaag      480

gaacagaaag acccttactt tgtggagacc ccctatggtt atcaactaga cttagatttc      540

ctcaaatatg tggatgacat acagaaggga aataccatca aaagactgaa catccagaag      600

aggcggaagc cgtccgtgcc atgcccagaa cccaggacca catctggtca gcaaggtata      660

tggacttcca ctgaatccct ctcatcctcc aacagtgatg acaacaagca gtgccccaac      720

ttcctcatag ccagaagtca agttacatca actccaatct caaagccacc tccccctctg      780

gagacctcac tcccttttct taccatccca gaaaatcgac agctgccacc tccctcacca      840

caactcccaa agcataacct tcatgtcacc aagacactga tggagacccg gagaagactg      900

gaacaggaga gagccaccat gcagatgaca ccgggtgagt tcagaaggcc caggctggcc      960

agttttggag gcatgggcac cacaagctcc ctcccttctt ttgtgggttc tggaaaccac     1020

aatcctgcca agcaccagct tcagaatgga taccaaggta atggggatta tggtagctat     1080

gccccagctg ctcccaccac ttcctccatg gggagctcca tccgccacag ccccctgagc     1140

tcagggatct ccaccccagt gaccaacgtg agccccatgc acctgcagca catccgcgag     1200

cagatggcca ttgctctgaa acgcctgaag gagctggagg agcaggtgcg aaccatccct     1260

gtgctccagg taaagatctc tgtcttgcaa gaagagaaaa ggcagttggt ctcacagctg     1320

aaaaaccaaa gggctgcatc ccagatcaat gtctgtggtg tgaggaagcg gtcctatagt     1380

gcggggaacg cctcccagct ggaacagctc tcccgggccc gaagaagtgg cggggaatta     1440

tacattgact atgaggagga agaaatggag accgtagaac agagcacgca gaggataaag     1500

gagttccggc aacttacagc agacatgcaa gccctggagc agaagatcca ggacagcagc     1560

tgtgaggcct cctcagagct cagggagaat ggagagtgcc ggtctgtggc tgtgggtgcc     1620

gaggagaaca tgaacgacat cgtcgtgtac cacagaggct ccaggtcctg taaggatgca     1680

gctgtaggga cacttgttga gatgagaaat tgtggggtca gcgtgacaga ggccatgctt     1740

ggagtgatga ctgaagctga caaagaaatt gagctgcaac agcagaccat agaatccttg     1800

aaggaaaaga tctatcgcct agaagtacag cttagagaaa ccacccatga ccgggagatg     1860

actaaactga aacaagagct gcaggctgct ggatcgagga aaaaggttga caaagccacg     1920

atggcccagc cgcttgtttt cagtaaggtg gtggaggcag tggtgcagac cagagaccaa     1980

atggtcggca gtcacatgga cctggtggac acgtgtgttg ggacctccgt ggaaacaaac     2040

agtgtaggca tctcctgcca gcctgaatgt aagaataaag tcgtagggcc tgagctgcct     2100

atgaattggt ggattgttaa ggagagggtg gaaatgcatg accgatgtgc tgggaggtct     2160

gtggaaatgt gtgacaagag tgtgagtgtg gaagtcagcg tctgcgaaac aggcagcaac     2220

acagaggagt ctgtgaacga cctcacactc ctcaagacaa acttgaatct caaagaagtg     2280

cggtctatcg gttgtggaga ttgttctgtt gacgtgaccg tctgctctcc aaaggagtgc     2340

gcctcccggg gcgtgaacac tgaggctgtt agccaggtgg aagctgccgt catggcagtg     2400

cctcgtactg cagaccagga cactagcaca gatttggaac aggtgcacca gttcaccaac     2460

accgagacgg ccaccctcat agagtcctgc accaacactt gtctaagcac tttggacaag     2520

cagaccagca cccagactgt ggagacgcgg acagtagctg taggagaagg ccgtgtcaag     2580

gacatcaact cctccaccaa gacgcggtcc attggtgttg gaacgttgct ttctggccat     2640

tctgggtttg acaggccatc agctgtgaag accaaagagt caggtgtggg gcagataaat     2700

attaacgaca actatctggt tggtctcaaa atgaggacta tagcttgtgg gccaccacag     2760

ttgactgtgg ggctgacagc cagcagaagg agcgtggggg ttggggatga ccctgtaggg     2820

gaatctctgg agaaccccca gcctcaagct ccacttggaa tgatgactgg cctggatcac     2880

tacattgagc gtatccagaa gctgctggca gaacagcaga cactgctggc tgagaactac     2940

agtgaactgg cagaagcttt cggggaacct cactcacaga tgggctccct caactctcag     3000

ctcatcagca ccctgtcgtc tatcaactct gtcatgaaat ctgcaagcac tgaagagctg     3060

aggaaccctg acttccagaa aaccagtctg ggtaaaatca caggcaatta tttgggatat     3120

acctgtaagt gtgggggcct tcagtcagga agtcccttaa gctcccagac atcccagcct     3180

gagcaagaag tggggacctc agaaggaaag ccaatcagca gcctggatgc cttccccact     3240

caggaaggta cgctgtctcc agtgaacctg acagacgacc agatcgccgc tggcctctat     3300

gcatgtacaa acaatgaaag tacactgaag tccatcatga agaagaaaga tggtaacaaa     3360

gattcaaatg gcgcaaaaaa gaatcttcag tttgttggca ttaatggagg gtatgaaaca     3420

acttcaagtg atgattccag ctcagatgaa agctcttctt ccgagtcaga tgacgagtgt     3480

gatgtcattg agtatcctct tgaagaagag gaggaggagg aggatgaaga cactcgggga     3540

atggcagaag ggcaccatgc agttaatatt gaaggtttga agtctgccag ggtggaagat     3600

gaaatgcagg ttcaagaatg tgaacctgag aaggtggaaa tcagagagag gtatgaatta     3660

agtgaaaaga tgttgtctgc atgcaactta ctgaaaaata ctataaatga ccccaaagct     3720

ttgaccagca aagatatgag gttctgtctg aacaccctcc agcacgagtg gttccgcgtg     3780

tccagtcaga agtcagccat tccagccatg gtgggggact acatagctgc ttttgaggcc     3840

atttccccag atgtcctccg ctatgtcatc aacttggcag acggcaacgg caacacagcc     3900

ctccattaca gcgtgtccca ctccaacttc gagattgtga agctgctgtt agatgccgat     3960

gtgtgtaatg tggatcacca gaacaaggca ggctacaccc ccatcatgtt ggcggccctc     4020

gccgctgtgg aagcagagaa ggacatgcgg attgtggaag aactcttcgg ctgtggggat     4080

gtgaatgcca aagctagtca ggcgggacag acggccctca tgctggcggt cagtcacgga     4140

cggatagaca tggtgaaggg ccttctggcc tgtggggctg atgtcaacat ccaggatgac     4200

gagggctcca cggccctcat gtgtgccagc gagcacgggc acgtggagat tgtcaagctg     4260

ctgctggccc agcccggctg caacggtcac ctagaggaca acgatggcag cactgcgctc     4320

tcaatcgccc tggaagcagg acacaaggac atcgctgttc ttctgtatgc ccatgtcaac     4380

tttgcaaaag cccagtctcc gggcacccct aggcttggaa ggaagacgtc tcctggcccc     4440

acccaccgag gttcatttga ttgattgtat gcaaatagcc ctttatttac atgccactat     4500

taagctgcta attgttcctg ttggggtgac agatactgaa tgtatacgta ttgtgcctga     4560

gctcaccagc aaacagaagc atcaagccca ggggtaaagg ctgaagcttt cacagtgcag     4620

agactgctag cctgggcaca cacacctcct ttctggccgt cttctgtgta gggcacactt     4680

taacccagtc tctgttgctg ttgagtctct gctccgtttt gtacagtcac agggaattct     4740

gatctgaagg ggcaccttct gttcactccc acaaagtggt gtctggttct cactgagacg     4800

ttttaagatt tttccacaaa tatttatatg tactaaatgt ggaaccatta gaaagttctt     4860

ccaaaatctc attccagcat agttttggat ttttcttttg tcttatttta aaataaggaa     4920

gtcgagatga ctttgatcat tggtaacttg ggcctgggcc agacaaagta taaaacttac     4980

aaaagaatat tctcatttgg tcttaactag gtagatgtaa tatatgactt tttataaaaa     5040

gggtatctat atgaacttga cacagtattt tcagcttttg tattccatac taaagccatg     5100

aagaactaca cgtaacatca tcatttgtat taattgcaca actccaatgc taaaggttgg     5160

attgtgttag aggaatcggc tctgtatttg cctctagaga aacacagtgt tctctttgta     5220

tttatggatt cctttttacc gtgtcacatt tactttggtc ctctatgtat ttaaatgttt     5280

gaagtgcctt agactcttgc catattttca aaataaaatt ccattaagct cttttaaaaa     5340

aaaaaaaaaa aa                                                         5352


<210>  202
<211>  2102
<212>  DNA
<213>  homo sapiens

<400>  202
agatctcatt ccgcctccct ctgtcgtcgc cccttcccaa ttctcgcgag acctcaagga       60

gcacagcttc tgcgcaccgc acgatactgg gagtccaggc gccaagggag ggggaaggga      120

aaaggggaaa cggtgcaaac ggcgtggccg ccatcttgct tgtgcccccg cttcgcgcgc      180

gctccgttct ccgtgacgca cacttccccc tcccctccgc cgcgcctggg cctctgcatt      240

gcccgactcc gtaggagcgc gggggcggct cctgctcttc ctggactcct gagcagagtt      300

gtcgagatgt ccacagaagg aggatttggt ggtactagca gcagtgatgc ccagcaaagc      360

ctacagtcgt tctggcctcg ggtcatggaa gaaatccgga atttaacagt gaaagacttc      420

cgagtgcagg aactcccact ggctcgtatt aagaagatta tgaaactgga tgaagatgtg      480

aagatgatca gtgcagaagc gcctgtactc tttgccaagg cagcccagat ttttatcaca      540

gagttgactc ttcgagcctg gattcacaca gaagataaca agcgccggac tctacagaga      600

aatgatatcg ccatggcaat tacaaaattt gatcagtttg attttctcat cgatattgtt      660

ccaagagatg aactgaaacc tccaaagcgt caggaggagg tgcgccagtc tgtaactcct      720

gccgagccag tccagtacta tttcacgctg gctcagcaac ccaccgctgt ccaagtccag      780

ggccagcagc aaggccagca gaccaccagc tccacgacca ccatccagcc tgggcagatc      840

atcatcgcac agcctcagca gggccagacc acacctgtga caatgcaggt tggagaaggt      900

cagcaggtgc agattgtcca ggctcagcca cagggtcaag cccaacaggc ccagagtggc      960

actggacaga ccatgcaggt gatgcagcag atcatcacta acacaggaga gatccagcag     1020

atcccggtgc agctgaatgc cggccagctg cagtatatcc gcttagccca gcctgtatca     1080

ggcactcaag ttgtgcaggg acagatccag acacttgcca ccaatgctca acagattaca     1140

cagacagagg tccagcaagg acagcagcag ttcagccagt tcacagatgg acagctctac     1200

cagatccagc aagtcaccat gcctgcgggc caggacctcg cccagcccat gttcatccag     1260

tcagccaacc agccctccga cgggcaggcc ccccaggtga ccggcgactg agggcctgag     1320

ctggcaaggc caaggacacc caacacaatt tttgccatac agccccaggc aatgggcaca     1380

gccttcctcc ccagaggacc cggccgacct cagcgcctcc tgcaggctag gacactggtg     1440

cactacaccc catgcctggg ggccgagatt ctccagcaga aagatgcaat attttttgtt     1500

tccttttttt ccattttttt ctctaaggaa tcaatatttc aatatgttga gtgtgtgtcc     1560

aatgctatga aattaaaata ttaaataaca tatttatggc attttcttga agagtgtggt     1620

tgaagaaata tttctccttt tgtttttctt ttttttttgt ttgttactgc cacttctttt     1680

taggagcaaa tctccccagg ggtgtacggt atttcttgac tctgggaaca gctgctaccc     1740

ccaagacttg ccacgttgtt ctgccctcag atggaattag gtgaatgtgt gtagctgctt     1800

tttcactcgt ggtcctctcc ccatcccttg ctctgacccc agagctctgt gtatttgcat     1860

ccagaggcca tggaaacatt ctttgcattt aagagacaga tttattccct gtggagagtg     1920

ggtggattca ttgccacact cttttctccc agggacccag gaaactagga ctttgtgtgt     1980

ttgctgccca cctccctttt attttttaaa tgcattaaaa actgtgctag tctcctttgc     2040

atggacttca agctgcatga aatgcaataa atctcatttt agataaaaaa aaaaaaaaaa     2100

aa                                                                    2102


<210>  203
<211>  4362
<212>  DNA
<213>  homo sapiens

<400>  203
gttgcggtgg ccaatagacg cattcggaac atcggcggct gcccgggtga cttggttata       60

tgtcacagaa taacattcga gaatgggaca tggaatgagg cgacggcccc agcaagcccc      120

agcagcccca gccccagccc caggcccagc agcagcagca gcagcccctg ctctcccgcc      180

gcccggagag gctctgcagc catgaagcca accgtcccga ggcaccgccg gtaagcaggg      240

agcctccgcg gagctcccgc cgccgctccc ccttggtgag tcctgccgca gcgagaggca      300

tggagaaggc cgcccccgcg gggcgctgat cccctcgccg cgcccgcgcg cacacgcccc      360

ccgccgccgc cgccgctgcc gccgccgcgc gcccccagta cctcgctccc cgcccaggcc      420

ccaccatgac cggctccgcg gccgacactc accgctgccc ccaccccaaa ggcgccaaag      480

gcacccggtc ccggagcagc cacgcgcggc ccgtgagcct cgccaccagc gggggctcag      540

aggaggagga caaagacggc ggggtgctgt tccacgtcaa caagagcggc ttccccatcg      600

acagccacac ctgggagcgc atgtggatgc acgtggccaa ggtgcaccct aaggggggag      660

aaatggtggg cgccatcagg aacgccgcct tcttggcaaa gccttcaata ccccaggtcc      720

caaactacag gctgtcgatg acgatcccag actggctcca ggcgatccag aattacatga      780

agaccctaca ctacttaacc aatgggcagc cttccattga gcggttcccc atcagcttta      840

aaacctactt ctcaggaaac tactttcacc acgttgtgct ggggatttac tgcaatggcc      900

gctatggctc attgggcatg agccgcaggg ctgagctgat ggacaagcca ttgacttttc      960

ggactctgag tgacctcatc tttgactttg aggactctta caagaaatac ctgcacacag     1020

tcaagaaggt caagattggg ctgtacgtcc cccatgagcc tcatagcttc cagcccattg     1080

agtggaagca gctggtcctc aacgtctcaa agatgctgag ggctgacata aggaaggagc     1140

tggagaaata tgccagggac atgagaatga agatcctgaa acctgcaagt gcccactctc     1200

cgacccaagt gagaagccgg ggaaaatccc tgtcccccag aaggagacag gcaagccccc     1260

cgaggaggct cggccggcga gagaagtcgc ctgcactgcc tgaaaagaag gtggctgatc     1320

tgagcactct gaatgaagtg ggctatcaaa tccgaattta gccaagccat accggccagc     1380

aagagggttt ctgtggtgct tctctctgca ctttacccag catcttcagg aggaactgca     1440

actatttatt aagaacttgt gaattttatt tttaaggatt cacctggaaa tagaatctga     1500

gtgggtggta accattagct ttaaaaaatt cactaaaagg caccatgaaa aggctgaagt     1560

aataagcccc actggggttg gactatgtcc ctcactcaag atcttaagga taaccgtaac     1620

tgaagtttta tatttttcca tttacctact ttcttttact tgctttgaac attatgcctc     1680

accaatagta aatgttcatg aaataatctc ttgaactttt ggtatagtaa ggtaactcta     1740

acagtattac tgtctttttc agcaataaca gaaagcaaaa atgggtgggt tttttttaag     1800

cagttattac ctcagcattt tgacatcaga tatgcaaact taatggcgtt ttgttttttt     1860

atattctatt tgtattcttt ccccagtatt tcccatgggg atctccacaa gtttggagtt     1920

ttttcctggt gcacacacgt gaggagattt aaggtactat atgcaagtgt tttactaaaa     1980

agcactgaaa ttcttctggc aatacaagaa ccattttcag gatcttggag ttacttcctt     2040

cttaatcttt cttaaagcat tcactgatgt ttttgttttt tcaaaatgaa acaaaaatat     2100

cacattgaga agctagtcta tgttctgtca ctaacattta aactttgcag actctaacaa     2160

aaagcacaag aggtcacgta ctattataca aatttagcgg tactggattt acctctgaca     2220

ttaacacact caggcagaga ccaggagtga tcagcaggtc ttcagaacca aaaaaccttt     2280

ctgttcacat ttcatctgat ttttaaactg aggcaggctt tgattcttct gaaggatgcc     2340

aagaatcaaa ctaagggagg actcactgtt aaagatgtgt tctgatgtct tatattaaga     2400

ccaaatgtga catgatgtga ttatcttcca gtactttgct tttaggtacc atttcatgac     2460

attttaggaa tgagtattgg aaaatataaa gaattagaaa agcagcactt tttttttaat     2520

ggaaaagtct tcggtccagt gttacacctt atagtgtaat tcagtcccta agcacagaat     2580

gaatgtctgg cctgcatatg gtagttacag tgtaacctct ggctgcagac cacacaggac     2640

aaccctaaca gcctagtctt gtatggtgta aatatcaaga gtacagcttc aatttcattt     2700

gctttatctt agcaacaatg ccaactcagg agagcagacg gccgatttca gtgaagtctg     2760

gtagtcaaca gatgttattt cagtctcagt gcatctcctc tggctttctt tgactgaagg     2820

tgtttatagg aaggaagtta aaaaaaaaaa aagctcattg agattcttta ccaattcttt     2880

acaagatttc tgggggtgac agggaaagca aaaggacttc aaagcaaaag ggtgcacaag     2940

agcttacttc accctgaaaa tcagtattat taatgaaaag tactgttttc ttaaagaagt     3000

cgaatgtcct ttagatgaac aagaccaagt atacatctcc attagattaa aatgtagcac     3060

agggttaaaa attatcagtt taatctcttt aagaacagta ttatcagagt ttaaaatgag     3120

ttagctctgt ttatctacac acagcaaacc cattcgcagc ctcttggcca catgtattca     3180

gatgtttgaa atagtgaatc atttcatttt cattctaaaa caatactgac ttagccatat     3240

accttctgtt tgtcaatctg aaacttgctt acatctaata agtagacctc ttataacact     3300

gcaaccattc taagagttgg aatttatttt tgccaagtat taagtactgt tacatctaaa     3360

atacagaatg tcaaatggtt gcatagcttg tttcccacaa caaggaggaa aagaacagga     3420

atacaaactc tgtaatatgc tgataaagaa gccttagaac tgccaactgg cttgatggtt     3480

caattagtaa gctaatttct cccacacccg ctccttgatt tttagactaa ttttcccaaa     3540

gcaaggttta gtcacacaaa cttgaaagta catttaaaat gttcttagtt gtcatcctac     3600

ttttattgcc tatggaatat gctaatttct aaaaaaaata cgggagaggc accaaacccc     3660

taaattctag tgcaataatt taaaaaacaa aaaacaaaac aaaacaaaaa acatgttata     3720

tgcacccccc tcccaaagct gattttaaga ctggctagaa ttcaaaatat aaaaaataaa     3780

actatgaagt gatttgaaat cggttttaaa aagttgttag tgcaagagaa attttatgtt     3840

taagccatca tggcaatata tgcaaagttt aaatgaatga cagaaatctt gattttagac     3900

tgtatgttgt gctgttttga gtacacttta tttcggagat atttagtatt ttctatacac     3960

tctgaaatca tgagcatttc actttttcta agtcaattat ttcataagga ttttattaat     4020

agatattggt aaatagaact ttggaaatct taattcagaa ttcttactat acctgagtct     4080

tttgtaagct atagttttat gtacaacctt gtacagtttt tttgacatac aattcagaac     4140

tttgtttatt ctcttggact ttgttctggc caatacattt tttttaaatc tttaagaaga     4200

actgtgattg ttttagtggg tatttttcta attaaatgaa aacttgtata atggtatttt     4260

agagaatgcc agtaagtgca tgtttcaagt taatgttttt ctcatcactt gtatgtttct     4320

aacacagcat gggactttaa taaaaccatc ctggaaactt aa                        4362


<210>  204
<211>  4928
<212>  DNA
<213>  homo sapiens

<400>  204
gcggggcgcg gcggcaggaa ctttcccggg gacccctgcg ggaaggcctg gccagtaagc       60

gcgcctcttt ggcccgaatc aacatggaaa cctaaggaaa aacgtctgac ctgcggaggt      120

agtttgggtg gctacttggt gttggacttg gctaaataaa taccagaggc agataaaaca      180

agcgaggggc ctaggtcaag agttccaagt ttgttcctcg ataaaaaacg acaaacgcgg      240

tcgggggcgg tgatgcccgc ctgcagtccc aacactttag gaagctgagg cggggggatc      300

gcaggagttc gagaccagtc tgggcaacat aatgagacca tccccaccac ctcccgtcct      360

taattttttt taataaaaaa aatctttaag tgagaaatgc atctgtaatg tccttattaa      420

ccaaaaacgc ctaagggata aagaagcaca cgctccctag ccaacgctag aggaacacac      480

cccgagagct ggtgctgtag gacccagttt tcccgcgaaa acgctgccgc gcagggggtc      540

agaccatctg gaccaagggg ggccgagcga ggcctacttc tggtttacgc acgggcgctg      600

aaagaagcgg cactgtcccc ccctgccgat gcgcagtggc gcctcccgga ggcggagcca      660

cgtacgagcg ccgctgtgat tggtgaggcc ccgccagggg cggagacgac cttgccgccg      720

gcgggaactc tgggtctcgc ggtttgggag cgctactcgc caggtggact cggagtccgc      780

gagcgtcgtc ggcaagcggc cgcctttcca cggtaaccgc gcgccggcgg ggagggcgtg      840

gcgcggagcc gacgggaacg tccgcgctgc ggagcagggc agggaagccg ggaggcgggc      900

ccggcccgag cttgtccttg tcgcgcaggt actccgagca ctatgtcgtc cccggcgtcg      960

accccgagcc gccgcggcag ccggcgtgga agggccaccc ccgcccagac gcctcggagt     1020

gaggatgcca ggtcatctcc ctctcagaga cgtagaggcg aggattccac ctccacgggg     1080

gagttgcagc cgatgccaac ctcgcctgga gtggacctgc agagccctgc tgcgcaggac     1140

gtgctgtttt ccagccctcc ccaaatgcat tcttcagcta tccctcttga ctttgatgtt     1200

agttcaccac tgacatacgg cactcccagc tctcgggtag agggaacccc aagaagtggt     1260

gttaggggca cacctgtgag acagaggcct gacctgggct ctgcacagaa gggcctgcaa     1320

gtggatctgc agtctgacgg ggcagcagca gaagatatag tggcaagtga gcagtctcta     1380

ggccaaaaac ttgtgatctg gggaacagat gtaaatgtgg cagcatgcaa agaaaacttt     1440

cagagatttc ttcagcgttt tattgaccct ctggctaaag aagaagaaaa tgttggcata     1500

gatattactg aacctctata catgcaacga cttggggaga ttaatgttat tggtgagcca     1560

tttttaaatg tgaactgtga acacatcaaa tcatttgaca aaaatttgta cagacaactc     1620

atctcttacc cacaggaagt tattccaact tttgacatgg ctgtcaatga aatcttcttt     1680

gaccgttacc ctgactcaat cttagaacat cagattcaag taagaccatt caacgcattg     1740

aagactaaga atatgagaaa cctgaatcca gaagacattg accagctcat caccatcagc     1800

ggcatggtga tcaggacatc ccagctgatt cccgagatgc aggaggcctt cttccagtgc     1860

caagtgtgtg cccacacgac ccgggtggag atggaccgcg gccgcattgc agagcccagt     1920

gtgtgcgggc gctgccacac cacccacagc atggcactca tccacaaccg ctccctcttc     1980

tctgacaagc agatgatcaa gcttcaggag tctccggaag acatgcctgc agggcagaca     2040

ccacacacag ttatcctgtt tgctcacaat gatctcgttg acaaggtcca gcctggggac     2100

agagtgaatg ttacaggcat ctatcgagct gtgcctattc gagtcaatcc aagagtgagt     2160

aatgtgaagt ctgtctacaa aacccacatt gatgtcattc attatcggaa aacggatgca     2220

aaacgtctgc atggccttga tgaagaagca gaacagaaac ttttttcaga gaaacgtgtg     2280

gaattgctta aggaactttc caggaaacca gacatttatg agaggcttgc ttcagccttg     2340

gctccaagca tttatgaaca tgaagatata aagaagggaa ttttgcttca gctctttggc     2400

gggacaagga aggattttag tcacactgga aggggcaaat ttcgggctga gatcaacatc     2460

ttgctgtgtg gcgaccctgg taccagcaag tcccagctgc tgcagtacgt gtacaacctc     2520

gtccccaggg gccagtacac gtctgggaag ggctccagtg cagttggcct cactgcgtac     2580

gtaatgaaag accctgagac aaggcagctg gtcctgcaga caggtgctct tgtcctgagt     2640

gacaacggca tctgctgtat cgatgagttc gacaagatga atgaaagtac aagatcggta     2700

ttgcatgaag tcatggaaca gcagactctg tccattgcaa aggctgggat catctgtcag     2760

ctcaatgcgc gcacctctgt cctggcagca gcaaatccca ttgagtctca gtggaatcct     2820

aaaaaaacaa ccattgaaaa catccagctg cctcatactt tattatcaag gtttgatttg     2880

atcttcctct tgctggaccc tcaggacgaa gcctatgaca ggcgtctggc tcaccacctg     2940

gtcgcactgt actaccagag cgaggagcag gcagaggagg agctcctgga catggcggtg     3000

ctaaaggact acattgccta cgcgcacagc accatcatgc cgcggctaag tgaggaagcc     3060

agccaggctc tcatcgaggc ttatgtagac atgaggaaga ttggcagtag ccggggaatg     3120

gtttctgcat accctcgaca gctagagtca ttaatccgct tagcagaagc ccatgctaaa     3180

gtaagattgt ctaacaaagt tgaagccatt gatgtggaag aggccaaacg cctccatcgg     3240

gaagctctga agcagtctgc aactgatccc cggactggca tcgtggacat atctattctt     3300

actacgggga tgagtgccac ctctcgtaaa cggaaagaag aattagctga agcattgaaa     3360

aagcttattt tatctaaggg caaaacacca gctctaaaat accagcaact ttttgaagat     3420

attcggggac aatctgacat agcaattact aaagatatgt ttgaagaagc actgcgtgcc     3480

ctggcagatg atgatttcct gacagtgact gggaagaccg tgcgcttgct ctgaagcctt     3540

gtgagcaagg aaggctccct gcatgtcctg cttgctgcac gccacatggg tgtggtctgc     3600

atctcagttg gccgccatca gtgtaaatag agcttaaagt catggtttgg ctgcataaaa     3660

attttctaac ttgggttcaa tatttgtagt gaagtatctg ttttcatttt tttcacgtta     3720

taaataaaaa tactatgctg gccgggcgcg gtggctcaca cctgtaatcc cagcactttg     3780

ggaggccaat gtgggtggat catgaggtca ggagttcaag accagcctag ccaagatggt     3840

gaaaccccgt ctctagtaaa gataacaaaa aattagctgg gcttgatggc atgcgcctgt     3900

aatcccagct actcgggagg ttgaggcagg agaatcgctt aaacccaggc ggcagaggtt     3960

gcagtgagcc aagatcgcgc cactgcactc cagcctcagc aatagagtga gactgtctca     4020

aaaaaaaaaa aaaaaaaaaa acctgccaat tttcaaacat accgtagaga ttattttcag     4080

gtgccatttt atagtatagc agcagggctt ttactctgtg tatgcacaga tgcagtctgg     4140

ggcatggttt gtgtgctgga ctttctcatg gccatcatca gtatgcttat ggatttgatg     4200

acaggcatag cctgggcata tcacctcatt ggtaaagggc tagagccttt cttttttatg     4260

gcacttcttt ttttgagata gggtcttact ctgtcaccct ggctagagta cactggtaca     4320

atcacggctc aatgtaggct taacctcctg ggctcaggtg tatgtcacta tgcccggcta     4380

ctttttgtat tttttggtag agacggcttc gccacgttgc ccaggctgca agcgatatgc     4440

ctaggctcaa gcgatctgcc cacctcaact tccggaagtg ctgagattac aggtgtgagc     4500

cactgcaccc agcctttgtt ttatttttta ttttttgaga ggtatgattc tttctagaga     4560

ttttttctca tggctactat tagatcagga atgggtgatt ggagattatt agattctagg     4620

ttaacttcta ccactttacc ctaatacata aaactttttc ctaaataaat gatggaagga     4680

ataatacttg gttacctggc attatttttc agtaagaaaa aagctttact aaccactaca     4740

tttatggaaa tttgtagggg taagtatttt ataggtcata aaaaacacca taatataacg     4800

aatctcattt tctttaaatg tgaattaaat cctaacagtc atctttataa aatgaccata     4860

ggctaaaatc ttacgtgtaa gtactactac aataaataat ttctgaaacc tttaaaaaaa     4920

aaaaaaaa                                                              4928


<210>  205
<211>  4800
<212>  DNA
<213>  homo sapiens

<400>  205
gcggggcgcg gcggcaggaa ctttcccggg gacccctgcg ggaaggcctg gccagtaagc       60

gcgcctcttt ggcccgaatc aacatggaaa cctaaggaaa aacgtctgac ctgcggaggt      120

agtttgggtg gctacttggt gttggacttg gctaaataaa taccagaggc agataaaaca      180

agcgaggggc ctaggtcaag agttccaagt ttgttcctcg ataaaaaacg acaaacgcgg      240

tcgggggcgg tgatgcccgc ctgcagtccc aacactttag gaagctgagg cggggggatc      300

gcaggagttc gagaccagtc tgggcaacat aatgagacca tccccaccac ctcccgtcct      360

taattttttt taataaaaaa aatctttaag tgagaaatgc atctgtaatg tccttattaa      420

ccaaaaacgc ctaagggata aagaagcaca cgctccctag ccaacgctag aggaacacac      480

cccgagagct ggtgctgtag gacccagttt tcccgcgaaa acgctgccgc gcagggggtc      540

agaccatctg gaccaagggg ggccgagcga ggcctacttc tggtttacgc acgggcgctg      600

aaagaagcgg cactgtcccc ccctgccgat gcgcagtggc gcctcccgga ggcggagcca      660

cgtacgagcg ccgctgtgat tggtgaggcc ccgccagggg cggagacgac cttgccgccg      720

gcgggaactc tgggtctcgc ggtttgggag cgctactcgc caggtggact cggagtccgc      780

gagcgtcgtc ggcaagcggc cgcctttcca cggtactccg agcactatgt cgtccccggc      840

gtcgaccccg agccgccgcg gcagccggcg tggaagggcc acccccgccc agacgcctcg      900

gagtgaggat gccaggtcat ctccctctca gagacgtaga ggcgaggatt ccacctccac      960

gggggagttg cagccgatgc caacctcgcc tggagtggac ctgcagagcc ctgctgcgca     1020

ggacgtgctg ttttccagcc ctccccaaat gcattcttca gctatccctc ttgactttga     1080

tgttagttca ccactgacat acggcactcc cagctctcgg gtagagggaa ccccaagaag     1140

tggtgttagg ggcacacctg tgagacagag gcctgacctg ggctctgcac agaagggcct     1200

gcaagtggat ctgcagtctg acggggcagc agcagaagat atagtggcaa gtgagcagtc     1260

tctaggccaa aaacttgtga tctggggaac agatgtaaat gtggcagcat gcaaagaaaa     1320

ctttcagaga tttcttcagc gttttattga ccctctggct aaagaagaag aaaatgttgg     1380

catagatatt actgaacctc tatacatgca acgacttggg gagattaatg ttattggtga     1440

gccattttta aatgtgaact gtgaacacat caaatcattt gacaaaaatt tgtacagaca     1500

actcatctct tacccacagg aagttattcc aacttttgac atggctgtca atgaaatctt     1560

ctttgaccgt taccctgact caatcttaga acatcagatt caagtaagac cattcaacgc     1620

attgaagact aagaatatga gaaacctgaa tccagaagac attgaccagc tcatcaccat     1680

cagcggcatg gtgatcagga catcccagct gattcccgag atgcaggagg ccttcttcca     1740

gtgccaagtg tgtgcccaca cgacccgggt ggagatggac cgcggccgca ttgcagagcc     1800

cagtgtgtgc gggcgctgcc acaccaccca cagcatggca ctcatccaca accgctccct     1860

cttctctgac aagcagatga tcaagcttca ggagtctccg gaagacatgc ctgcagggca     1920

gacaccacac acagttatcc tgtttgctca caatgatctc gttgacaagg tccagcctgg     1980

ggacagagtg aatgttacag gcatctatcg agctgtgcct attcgagtca atccaagagt     2040

gagtaatgtg aagtctgtct acaaaaccca cattgatgtc attcattatc ggaaaacgga     2100

tgcaaaacgt ctgcatggcc ttgatgaaga agcagaacag aaactttttt cagagaaacg     2160

tgtggaattg cttaaggaac tttccaggaa accagacatt tatgagaggc ttgcttcagc     2220

cttggctcca agcatttatg aacatgaaga tataaagaag ggaattttgc ttcagctctt     2280

tggcgggaca aggaaggatt ttagtcacac tggaaggggc aaatttcggg ctgagatcaa     2340

catcttgctg tgtggcgacc ctggtaccag caagtcccag ctgctgcagt acgtgtacaa     2400

cctcgtcccc aggggccagt acacgtctgg gaagggctcc agtgcagttg gcctcactgc     2460

gtacgtaatg aaagaccctg agacaaggca gctggtcctg cagacaggtg ctcttgtcct     2520

gagtgacaac ggcatctgct gtatcgatga gttcgacaag atgaatgaaa gtacaagatc     2580

ggtattgcat gaagtcatgg aacagcagac tctgtccatt gcaaaggctg ggatcatctg     2640

tcagctcaat gcgcgcacct ctgtcctggc agcagcaaat cccattgagt ctcagtggaa     2700

tcctaaaaaa acaaccattg aaaacatcca gctgcctcat actttattat caaggtttga     2760

tttgatcttc ctcttgctgg accctcagga cgaagcctat gacaggcgtc tggctcacca     2820

cctggtcgca ctgtactacc agagcgagga gcaggcagag gaggagctcc tggacatggc     2880

ggtgctaaag gactacattg cctacgcgca cagcaccatc atgccgcggc taagtgagga     2940

agccagccag gctctcatcg aggcttatgt agacatgagg aagattggca gtagccgggg     3000

aatggtttct gcataccctc gacagctaga gtcattaatc cgcttagcag aagcccatgc     3060

taaagtaaga ttgtctaaca aagttgaagc cattgatgtg gaagaggcca aacgcctcca     3120

tcgggaagct ctgaagcagt ctgcaactga tccccggact ggcatcgtgg acatatctat     3180

tcttactacg gggatgagtg ccacctctcg taaacggaaa gaagaattag ctgaagcatt     3240

gaaaaagctt attttatcta agggcaaaac accagctcta aaataccagc aactttttga     3300

agatattcgg ggacaatctg acatagcaat tactaaagat atgtttgaag aagcactgcg     3360

tgccctggca gatgatgatt tcctgacagt gactgggaag accgtgcgct tgctctgaag     3420

ccttgtgagc aaggaaggct ccctgcatgt cctgcttgct gcacgccaca tgggtgtggt     3480

ctgcatctca gttggccgcc atcagtgtaa atagagctta aagtcatggt ttggctgcat     3540

aaaaattttc taacttgggt tcaatatttg tagtgaagta tctgttttca tttttttcac     3600

gttataaata aaaatactat gctggccggg cgcggtggct cacacctgta atcccagcac     3660

tttgggaggc caatgtgggt ggatcatgag gtcaggagtt caagaccagc ctagccaaga     3720

tggtgaaacc ccgtctctag taaagataac aaaaaattag ctgggcttga tggcatgcgc     3780

ctgtaatccc agctactcgg gaggttgagg caggagaatc gcttaaaccc aggcggcaga     3840

ggttgcagtg agccaagatc gcgccactgc actccagcct cagcaataga gtgagactgt     3900

ctcaaaaaaa aaaaaaaaaa aaaaacctgc caattttcaa acataccgta gagattattt     3960

tcaggtgcca ttttatagta tagcagcagg gcttttactc tgtgtatgca cagatgcagt     4020

ctggggcatg gtttgtgtgc tggactttct catggccatc atcagtatgc ttatggattt     4080

gatgacaggc atagcctggg catatcacct cattggtaaa gggctagagc ctttcttttt     4140

tatggcactt ctttttttga gatagggtct tactctgtca ccctggctag agtacactgg     4200

tacaatcacg gctcaatgta ggcttaacct cctgggctca ggtgtatgtc actatgcccg     4260

gctacttttt gtattttttg gtagagacgg cttcgccacg ttgcccaggc tgcaagcgat     4320

atgcctaggc tcaagcgatc tgcccacctc aacttccgga agtgctgaga ttacaggtgt     4380

gagccactgc acccagcctt tgttttattt tttatttttt gagaggtatg attctttcta     4440

gagatttttt ctcatggcta ctattagatc aggaatgggt gattggagat tattagattc     4500

taggttaact tctaccactt taccctaata cataaaactt tttcctaaat aaatgatgga     4560

aggaataata cttggttacc tggcattatt tttcagtaag aaaaaagctt tactaaccac     4620

tacatttatg gaaatttgta ggggtaagta ttttataggt cataaaaaac accataatat     4680

aacgaatctc attttcttta aatgtgaatt aaatcctaac agtcatcttt ataaaatgac     4740

cataggctaa aatcttacgt gtaagtacta ctacaataaa taatttctga aacctttaaa     4800


<210>  206
<211>  5054
<212>  DNA
<213>  homo sapiens

<400>  206
gtgcgcccct ccgaacgtcc ccgggagccc agccagagcg agcgccgggg ccgggcgcgc       60

aggagtgaaa aggaggcggc ggccgcagct gcgagcaaca gatccggacg ccgcgagctg      120

acccgctctg ctgttgggcg attttttttt aattgcagaa aaatttatta aattggaaaa      180

tcttgcgttt ttcaatggcg ctggccccgg gtcagcgggc gattttctct gcatcaagat      240

gggctttgcc gtttccgtag tgggcaccag tggtggcctg attgtcagtc ttctcccggc      300

atttttaagg ccaggagccg agcgctgctt gtaggcgaat accctacaga gcggtttggc      360

tttttaaatt actgttatta ttttgggcag agaacagtcg gtctggtgca ccccgtcctc      420

gctgcagaag aggctgcgag tccgaggtgg gtctctcgga aggtgaaatt ccttctgggg      480

tgagcgagcc ccggccccgc gcgcagtcca gcggccccgc gtgtgtgccc tcgccctgcc      540

ggagccggga aaatggaggc tgtgattgag aaggaatgca gcgcgctcgg aggcctcttc      600

cagaccatca tcagcgacat gaaggggagc tatccagttt gggaagattt cataaacaaa      660

gcaggaaagc tgcagtccca gcttcggaca acagtagtag cagcagctgc cttcttggac      720

gcctttcaga aagtggctga catggccacc aacacacgtg gtgggaccag ggagattgga      780

tctgctctca ccaggatgtg catgaggcac agaagcattg aagccaagct gaggcagttt      840

tcgagcgctt taattgattg tctgataaac ccacttcaag aacagatgga agaatggaag      900

aaagtggcca accagctgga taaagaccac gcaaaagaat ataagaaagc ccgccaagag      960

ataaaaaaga agtcctcgga tacgctgaaa ctgcagaaga aagcaaaaaa agggagaggt     1020

gatatccagc ctcagttgga cagtgctctc caagatgtca atgataagta tctcttattg     1080

gaagaaacag aaaagcaggc tgtccggaag gctttgattg aagaacgtgg ccgattctgt     1140

accttcatct ctatgctgcg gccagtgatt gaagaagaaa tctcaatgct aggggaaata     1200

acccaccttc agaccatctc ggaagatcta aaaagcctga ccatggaccc tcacaaactg     1260

ccctcctcaa gtgaacaggt gattctggac ttgaaaggtt ctgattacag ctggtcgtat     1320

cagacgccac cctcttcccc cagcaccacc atgtccagaa agtccagtgt ctgcagcagc     1380

ctgaacagtg tcaacagcag tgactcccgg tccagcggct cccactcgca ttcccccagc     1440

tcacattacc gctaccgcag ctccaacctg gcccagcagg ctcctgtgag gctgtccagc     1500

gtgtcctccc atgactcagg attcatatcc caggatgcct tccagtccaa gtcaccatcc     1560

cccatgccgc cagaggcccc caaccagttg tctaacgggt tttctcacta tagtttatca     1620

agtgagtccc acgtggggcc cacgggtgca ggccttttcc ctcattgcct gcctgcctcc     1680

cgcctgctcc ctcgggtcac ctctgtccac cttccagact acgctcatta ttacaccatt     1740

gggcccggca tgttcccgtc atctcagatc cctagctgga aggactgggc taagcctggg     1800

ccctatgacc agcctctggt gaacaccctg cagcgccgca aagagaagcg agaaccggac     1860

cccaacgggg gaggacccac taccgccagc ggcccacctg cagcagctga ggaggctcag     1920

agaccacgga gcatgactgt atcggctgcc accaggcctg gtgaggagat ggaggcttgt     1980

gaggagctgg ccctggccct gtctcggggc ctgcagctgg acacccagag gagcagccgg     2040

gactcgcttc agtgctccag cggctacagc acccagacaa ccaccccctg ctgctctgag     2100

gacaccatcc cttcccaagt ttcagattat gattatttct ctgtaagtgg tgaccaggag     2160

gcagatcagc aggagttcga caagtcctcc accattccaa gaaacagcga catcagccag     2220

tcctaccgac ggatgttcca agccaagcgt ccagcctcaa ctgctggcct ccccaccacc     2280

ctgggacctg ctatggtcac tccaggggtt gcaactatcc gacggacccc ttccaccaag     2340

ccttctgtcc gccggggaac cattggagct ggtcccatcc ccatcaagac acccgtgatc     2400

cctgtcaaga ccccaaccgt cccagacctc ccaggggtgt tgccagcccc tccagatggg     2460

ccagaagagc ggggggagca cagccctgag tcgccatctg tgggtgaggg cccccaaggt     2520

gtcaccagca tgccctcctc aatgtggagc ggccaagctt ccgttaaccc tccacttcca     2580

ggcccgaagc ccagtatccc tgaggagcac agacaggcaa ttccagaaag tgaagctgaa     2640

gaccaggaac gggaaccccc aagtgccact gtctccccag gccagattcc agagagtgac     2700

cctgcagacc tgagcccaag ggatactcca caaggagaag acatgctgaa cgccatccga     2760

aggggcgtga aactgaagaa gaccacgaca aacgatcgct cagcccctcg cttttcttag     2820

gttcacaaga aatgcgccgg tggggaatga actgtttcat taataaaacc taatttgtct     2880

tgatccattc cactctataa taaaacaaaa gattttgtag gcaactcgga atatagctct     2940

tttgaaagta ctcgacacct ttagataaga attaaaacca acctatgtaa ctgacataat     3000

cttgatcttt taatttgtaa atattgacaa ttttctttct gcacatttta atcttagttt     3060

cccttttgat ttttctgaag gtgccaaatt ccatttaact tttttacaag tctttgtaaa     3120

attttaaatg cataaagggg gttggggcag gggaaccacg aagtagttaa ttttagaaaa     3180

ggatttacta tacttcactc ttcttttttt ttccccacaa gcttttgtag atgcattgta     3240

gtagtctagc ttagaagcaa atgcaagtta ttttaatgta caaactaaat gggtaagagg     3300

taaaatcttc atttaaatat actatgttct ggatgaaaag agcaggagta acaattgatg     3360

agcaatattc agagtgaagt aaatctggaa atggtagact gtgttgggat tggggggagg     3420

gccatgggag gggtacatcg tcaacatagc cgatcctgtt acatttaaga gtagcctcgt     3480

aggttgaatt tcttctggta gcttcatggt aaatgcatcc gaataagcca tactggattg     3540

cagtgtttgt ttctgtaggg tgtttaagga cttgacttcc tttctcccat gattcctctg     3600

gactgcacac agcacccaca accagcccca tgcatgctgc tgcctctggg cagtcgtaga     3660

atctcccact tcagtttctc gttgattgta ctcaccttta tggaatccaa atacatccaa     3720

aagggtaagg cagttttaaa aatgtgaaaa catttaaaaa tgataatagc agggaattct     3780

tagattatag taaatgcctt ttacttaact gtgcccagca ggctgggtgc gttaaaaagc     3840

ccaagtattt tgaaaaaact cgaacagatt tgacaagggt agccagcttg gagtctagca     3900

acttgccaat gtgtttacca atctgggggc ttgtttttct tttcttcttt caaataaatg     3960

gcagttaact ggctttacag taaacattga agagaggagg atttgtttat tgtcactggg     4020

aatctgacca ctatactgtc ctttttttgt attctgggta aatgtttttt ggaaaagatt     4080

tgtcttttct aagtggaagt taaatttgtt atactgccca tcccctaaag ccaacagaga     4140

tttgtagatt taaagggatc acatttgaag acaatagtgt ttaagaaagc aagcaagtcc     4200

cttagcagtc aggtcataac agggcacatt tctgaccgaa ccctctcaag gcagaggagg     4260

agtttggtgg gtttcataca ccctgcagat tcctgttggc tctaaccctc aattacctaa     4320

tcttatgctt taacacataa ctgcattgga tgtgagagta acgtaccgta tggtcattgt     4380

tctatatatt aacattgaac actgctgcga ttgctcaagg acattttatg ttacggcttt     4440

aaagcaaagg catgattatt agaaactatt taagcttttt tctttgaaaa acaagctcct     4500

tttacagaat ataaacaaca gtagtgcctg tggtttagcc caccaatctt gatgactaaa     4560

agtagctgat gcattgtgca tatgatgctt gagatggttt ttgcaaaagc agaaatcgct     4620

gcaaggtaat cacaatagat aaaagtggta ttttaaacct ttgaaataaa tggatgtaac     4680

tgtaccttgg tacagctttt cacttgttta gtttttaaac gttagtataa tctgaataaa     4740

taaaatgttg ccaaattcaa tgtagaaaga atgtgacaac acaccttggg tagttctgct     4800

tgtgtttttg catattgtaa aagcagtgtc acagctaaaa agaaagaaat cgtttctaac     4860

agtaaattat tgtgctttag ttgctagttt gtactgagag ttgacctctc cctgtgcagt     4920

tttttgttct aaacttgtat aaataacaat tgtgtaatgt gtctccctcc tacattgtaa     4980

caattgcttc agcctacgtt ataaataaag aaccactaga ttaaaaaagt cctgtatttc     5040

aaaaaaaaaa aaaa                                                       5054


<210>  207
<211>  5694
<212>  DNA
<213>  homo sapiens

<400>  207
agttgccctg tcagtgcagg tggaggcccc ggcggggcaa agtggcagga acctcttaaa       60

gggcgagagc ggcgcggagc cagaacgcgg tcggcccggt ccccgccgca cccagcccag      120

caacatcatg acaacagaga agagtttagt gactgaggcc gaaaattcac agcaccaaca      180

gaaggaagag ggtgaggaag ccataaactc aggccaacaa gaacctcagc aggaggaatc      240

ttgtcaaaca gcagctgaag gagataattg gtgtgaacag aagctgaaag cttctaatgg      300

agacactcct acacatgaag acttgaccaa gaacaaggag cggacatcag aaagcagagg      360

actttcacga ctattctcct cgtttctcaa aaggcccaaa tctcaggtgt ccgaggaaga      420

aggcaaagaa gtagagtcag ataaagaaaa aggtgaagga ggtcagaaag agatagaatt      480

tggaaccagt cttgatgaag agatcatttt aaaggcccca attgcagctc ctgaaccgga      540

actcaaaaca gacccatctt tggatcttca ttcattaagc agtgcagaaa cacagcctgc      600

tcaggaagaa ctcagagaag atccagattt tgaaattaag gaaggagaag gacttgaaga      660

gtgctccaaa atagaagtaa aagaagaaag ccctcaatca aaagcagaaa cagaattaaa      720

agcttcccaa aaaccaatca gaaaacacag gaacatgcac tgcaaggttt ctttgttgga      780

tgacacagtt tatgaatgtg ttgtggagac atggctggat tccgccaaag aaataaaaaa      840

gcaggttcgt ggtgtccctt ggaattttac atttaatgta aagttttatc cacctgaccc      900

agcacagtta acagaagaca taacaagata ttatttatgt cttcagcttc ggcaggacat      960

agttgcagga cgtctgccct gttcctttgc aaccttagca ttattaggtt cttacaccat     1020

ccagtctgaa ctgggagact acgacccaga actccatggc gtggattatg ttagtgattt     1080

taaactggcc ccgaatcaga ccaaggaact tgaagagaag gtcatggaac tgcataagtc     1140

atacaggtcc atgactccag ctcaggctga cttggagttt cttgagaatg ccaaaaagtt     1200

gtctatgtat ggagttgatc ttcataaagc aaaggacttg gaaggagtag atatcatcct     1260

aggtgtctgc tctagtggcc ttctggttta caaagataag ctgagaatta accgcttccc     1320

ttggcccaaa gtgctgaaga tttcttataa acgtagtagc tttttcatca agattcggcc     1380

tggagagcaa gagcagtatg aaagtaccat cggattcaaa cttcccagtt accgagcagc     1440

taagaaatta tggaaagtct gtgtagaaca tcacacgttt ttcagattga catctacaga     1500

caccattccc aaaagcaaat ttcttgcgct aggatccaaa tttcgataca gtggccggac     1560

tcaagctcag accaggcaag ctagtgctct aattgacagg cctgccccac acttcgagcg     1620

tacagcaagt aaacgggcgt cccggagcct cgatggagca gcagctgtcg attcggcaga     1680

ccgaagtcct cggcccactt ctgcacctgc cattactcag ggtcaggttg cagaaggtgg     1740

cgtcctagat gcctctgcta aaaaaacagt ggtccctaaa gcacagaagg aaacagtgaa     1800

ggctgaagtg aaaaaggaag acgagccacc tgagcaagct gagccagagc ccacagaagc     1860

atggaaggat ttagacaaga gtcaagagga gatcaaaaaa catcatgcca gcatcagtga     1920

gctgaaaaag aacttcatgg agtctgtacc agaaccacgg cctagtgaat gggataaacg     1980

cttatccact cactcaccct tccgaactct taacatcaat gggcaaatcc ccacaggaga     2040

aggacctccc ctggtgaaga cacaaactgt caccatctca gataatgcca atgctgtgaa     2100

aagtgaaatc ccaaccaaag acgtccctat tgtccacact gagaccaaga ccatcactta     2160

tgaggctgcc cagactgacg acaacagtgg agacttggac ccaggagtct tgctgacagc     2220

tcaaactatc acatctgaga ccccaagcag caccaccaca actcaaatta ccaagactgt     2280

aaaaggtggg atttcagaga cacgtattga aaagagaatt gtgatcacag gagatgctga     2340

tattgaccat gatcaggtcc ttgtacaagc catcaaggag gcaaaggagc agcacccaga     2400

catgtcagtg accaaggtgg tcgtccacca ggagaccgag attgctgatg agtgagctca     2460

ggaactaacc taccccaact ctgcccttct cccatccaag agaaaccagc aaaatgataa     2520

agaagctaac ctgccatagt cagacttcag actttcaaga ttattctaaa tcaccagaaa     2580

attaatttca gtttctattg ggagtttata ccaagagatt cttctagatc tcattgatcc     2640

ttttgaagag ctttttctat attaggatat cagaattgtt caacttttca ctctatagac     2700

tgttttaaga gttttggggt ttttttaatt gggtggtttg taaccccttc agcctagcct     2760

ctctgcccat ttatttccaa ccccaacaga cactgacagg gtccatggaa ttcttcggga     2820

aatcctccaa ggactcttgt cagctgtgtt ggaagccaaa gccagcttag tgggacttcc     2880

gcgtctctcc ctagtcttat cccctttgga tgatggcaga aacttcatga accagccctt     2940

tctcagagcc agtgatgtga gtgtatcaga atgccaggga gggcaccagc cctgatccac     3000

agacctcgga aagatgcccc tgttcctttg ttgcgggtgg ttttggtaag gcagagccct     3060

ctgctgagaa tgtagtattg tttttcccct ctccctcctg ctttcttttt ggagcttctt     3120

tgggtcaaag acatggaagt tgcttcagat atctgatact gtgaatgttt gaacatatcc     3180

gtggccttca cctctccagc taccctttta cctcatcaga agcagtggct cagctaagtg     3240

ctccccctag ctcccatctc aggagaccaa atctcacaga aaaataggca ctttgggcca     3300

aaagctctaa tggaacattt ttagtggtga tttggggaag gaaagttaat gaggttttta     3360

aaataaggtt ttctagtttt gagagtgtgc acttcacaca ggggaatggg gttacttctg     3420

tctgatcctg ggcctttctt tcatcccaaa tgacaaggaa tgtggctcag agaagggttt     3480

ttcttttttg acctttcttc tctcaacagg aacctgcctg aggacaccct tctagagcaa     3540

ggaattgact tttaggagcc gttctcccca caagacacca catgacaagg ggtataagcc     3600

ccagccctgc tcattcccac tcaccagctg aggtctgtca ggttttgaag gcttgatttt     3660

gtggtgggtt tggggcttag ttttcctttt tttcattttg atttttgaaa gtgaagatga     3720

tgccctaatt cctggtaagg atttggggca tagttttttg tttttttgag acggagtttc     3780

gctcttgttg cccaagctgg agtgcagtgg cgcgatctcg gctcactgca acctccgcct     3840

cctgggttca agcagttctc ttgcctcagc ctcccaagta gctgggatga caggcgcaca     3900

ccaccacgcc cagcaaattt tttgtatttt tagtagaaac gggatttcac cttgttaggc     3960

tggtctcgaa ctcctgacct caggtgatcc acccaccttg gcctcccaaa gtgctgggat     4020

tacaggtgtg agccaccacg cccggccgat ttggggcatt tttatttaac agaacttctc     4080

taaccttcca actgcttccc acaaacacat tggcctcaag gctccttaga atcccagttc     4140

cagcttccta aaatagacag tgggtatcgg gcagcagtca ctggggctca agggcagtga     4200

gcaagagaaa tgtctaaagc tgcttctccc aacaccgtcc aaagtctcca ctgcctgagt     4260

tttgtttcgg ctggtttgaa ctcatttcgg gtgtgtgcat ttttcttttg gtacccatgt     4320

gagacatgaa caacaggagg gagggaaaga gcccaggtgg gacgtgggac aggcttaggg     4380

gaaagagctt gtcctatctc aggaacaaaa ttataggctg tgggcagagg gtctgaaagg     4440

tgggctttgg ggtagtgccc aagcctggtc gtgttgccag gagtggtgac aagaaatgca     4500

gcttacatca aacgaacatg tagtgcatgc ccactgcctg atggccagat ggcctgtagg     4560

aagagctacc agggcttcca gacctgtgga acgaagagga tggggaaaag gcagagggca     4620

ctgagtgtcc ctttaaaaac taacccactg aatattccgt gtgatctaga acagtgtggc     4680

agctttcaca gcacaggacc gttcatcggg ggcctaaacg tttccctcag ctctgtcacc     4740

aactcacttc tctcggcttc gttgtctgta aattggatga aaagagctct aatgcctttc     4800

aggctcttag aagccataga tttggacaag cccagcaaga tgggtgtcct tccaggcctc     4860

ttcccctttc ctccatctct ggcaacagtt cttggggttt ggcaattgtt tggatttttt     4920

ttctttctgc agttgtgtgt atgtgtgttt gtgtgaagaa aaacagactc tgtccaggta     4980

gaaatggtga ggagggggaa gagaattaca tttccagggt cagaaacttg gcaacagttt     5040

tcctagagtg actcagacac accacagtaa caactctcgc tgcaatttta ttttaatttg     5100

agaaataaag atttcctcca agccacatga ggactctggc acccacccac aaagcaagac     5160

ctgtatttat aagccgaggg ctcagggagc ctaactgcgg gacccgtcag ggccccgtga     5220

cccatccccg tccccacccc cccctccacc gctgggccca tcagtgtgtg ttggggggat     5280

gcttggcagc tgggggtgag gagacaacaa acctcgggaa ctggagccag agctgcggcc     5340

tgactgacgc cttttgatgc tcacgggaaa tttctgccca ggatctcagc cccaggctgg     5400

ttgtttctac aaatctctct caaatgtatt attttggtga caaaaatgaa ggagctttgt     5460

aaattttttt taaaattatg aatcatatca agtagttgtt tacatttctt gaaaaaatag     5520

gaactcgggc agcagaatca gattggcaga atctttagac tacacaggca ataatcaagt     5580

ctgctgtttt ggcctttcgt agtagaagtg gttgtagtgt ttagatatct gtttggtctt     5640

gcttcttgta ttgcattttt ttcaataaac aacaacaaaa agaactctca aaaa           5694


<210>  208
<211>  953
<212>  DNA
<213>  homo sapiens

<400>  208
ggactagcag ttctctgcgg agggccggtt gatacagttc cggtgggaga acgcggctgc       60

gaggttttcg gctttggctc ctgatatgca gcgacagaat tttcggcccc caactcctcc      120

ttaccctggt ccgggtggag gaggttgggg tagcggaagc agcttccggg gaaccccggg      180

cgggggcgga ccacggccgc cctcccctcg agacgggtac gggagtccgc accacacgcc      240

gccgtacggg ccccggtcta ggccgtacgg gagcagtcac tctccgcgac acggcggcag      300

cttcccgggg ggccggttcg ggtctccgtc ccctggcggc taccctggct cctactccag      360

gtcccccgcg gggtcccagc agcaattcgg ctactcccca gggcagcagc agacccaccc      420

ccagggttct ccaaggacat ctacaccatt tggatcaggg cgtgttagag aaaaaagaat      480

gtctaatgag ttggaaaatt atttcaagcc ttcaatgctt gaagatcctt gggctggcct      540

agaaccagta tctgtagtgg atataagcca acaatacagc aatactcaaa cattcacagg      600

caaaaaagga agatactttt gttaacattt ctgaaattca actggaagct tcatgtgtca      660

ggaacatctt ggacaaaact ttaagttgtg ttgatataaa tttacccaaa gatgatgact      720

ttgattggat aattagtaag gtctttttgt tatttttcat cgtatcaggt attgttgata      780

ttagagaaaa aagtaggata acttgcaaca tttagctctg gaagtaccta ccacatttta      840

gagatttacc gtttccatat atttaacatt cctggttaca taatggacat ttgtctttta      900

atgttttttc aatgttttaa aataaaacat tttgtcttct aaaaaaaaaa aaa             953


<210>  209
<211>  1841
<212>  DNA
<213>  homo sapiens

<400>  209
agaatgattt cactacagac tctctggaaa gcctgggagc tgaattccgg aagatcccca       60

catcgatgaa agcaaagcga agccaccaag ccatcatcat gtccacgtcg ctacgagtca      120

gcccatccat ccatggctac cacttcgaca cagcctctcg taagaaagcc gtgggcaaca      180

tctttgaaaa cacagaccaa gaatcactag aaaggctctt cagaaactct ggagacaaga      240

aagcagagga gagagccaag atcatttttg ccatagatca agatgtggag gagaaaacgc      300

gtgccctgat ggccttgaag aagaggacaa aagacaagct tttccagttt ctgaaactgc      360

ggaaatattc catcaaagtt cactgaagag aagaggatgg ataaggacgt tatccaagaa      420

tggacattca aagaccaagt gagtttgtga gattctaaca gatgcagcat tttgctgcta      480

ccttacaagc ttctcttctg tcaggactcc agaggctgga aagggaccgg gactggaaag      540

ggaccaggac tgaacagact ggttacaaag actccaaaca atttcatgcc ctgtgctgtt      600

acagaggaga acaaaatgct ttcagcaagg atttgaaaac tcttccgtcc ctgcaggaaa      660

ggattgatgc tgatagaaga gcctggacag atgtaatgag aactaaagaa aacagatggc      720

tggagatgac atttatccag ggtcactttg tcaggcccta ggacttaaat cgaagttgaa      780

cttttttttt tttttttaac caaatagata ggggaaggga ggagggagag ggaggacagg      840

gagagaaaat accatgcata aattgtttac tgaattttta tatctgagtg ttcaaaatat      900

ttccaagcct gagtattgtc tattggtata gatttttaga aatcaataat tgattattta      960

tttgcactta ttacaatgcc tgaaaaagtg caccacatgg atgttaagta gaaattcaag     1020

aaagtaagat gtcttcagca actcagtaaa accttacgcc accttttggt ttgtaaaagg     1080

ttttttatac atttcaaaca ggttgcacaa aagttaaaat aatggggtct tttataaatc     1140

caaagtactg tgaaaacatt ttacatattt tttaaatctt ctgactaatg ctaaaacgta     1200

atctaattaa atttcataca gttactgcag taagcattag gaagtgaata tgatatacaa     1260

aatagtttat aaagactcta tagtttctat aatttatttt actggcaaat gtcatgcaac     1320

aataataaat tattgtaaac tttgtggctt ttggtctgtg atgcttggtc tcaaaggaaa     1380

aaataagatg gtaaatgttg atatttacaa acttttctaa agatgtgtct ctaacaataa     1440

aagttaattt tagagtagtt ttatattaat taccaaactt tttcaaaaca aattcttacg     1500

tcaaatatct gggaagtttc tctgtcccaa tcttaaaata taaaatatag atatagaagt     1560

tcatagattg actccttggc atttctattt atgtatccat taaggatgag ttttaaaagg     1620

ctttctcttc atacttttga aaaatttctt ctatgattac agtagctatg tacatgtgta     1680

catctatttt tcccaagcaa tatgttttgg gtttagagtc tgagtgatga ccaagattct     1740

gtgtgttact actgtttgtt taataggaac aaatatagaa ataatattat ctctttgctt     1800

atttcccgtt aaaactataa taaaatgttt ctaggacagc a                         1841


<210>  210
<211>  5561
<212>  DNA
<213>  homo sapiens

<400>  210
agggggccga ctggcgcggc tctggagagc gctcctccgc cccgcgcgcc gtccctgcgc       60

cccgctccgc ccgcgcctct ctcccagcgc cgcgcctcgg gcgtaaagag cgcgcccctc      120

gcaccgcagc cagtgccgac cgcagcagcc cagccccagc cttcctccgc ctccgcctct      180

ctctcctcct cctcctccgc cgccggacac gcagccgcag gccgggaccg ggacgcagct      240

ggggagtcag ggacgcgcgc agccagccct tccccctccg gctcccgcac cgccggccgc      300

ctcccctcgc cctcctactc tcccctccct gctccttcgc tttttcctcc tcctcctctc      360

ccggccccgg ctgccagcac catgtccgca gggggagatt ttgggaatcc actgagaaaa      420

ttcaagttgg tgttcttggg ggagcagagc gtcgggaaga cgtctctgat tacgaggttc      480

atgtacgaca gcttcgacaa cacataccag gcaaccattg ggattgactt cttgtcaaaa      540

accatgtact tggaggaccg cacggtgcga ctgcagctct gggacacagc tggtcaggag      600

aggttccgca gcctgatccc cagctacatc cgggactcca cggtggctgt ggtggtgtac      660

gacatcacaa atctcaactc cttccaacag acctctaagt ggatcgacga cgtcaggaca      720

gagaggggca gtgatgttat catcatgctg gtgggcaaca agacggacct ggctgataag      780

aggcagataa ccatcgagga gggggagcag cgcgccaaag aactgagcgt catgttcatt      840

gagaccagtg cgaagactgg ctacaacgtg aagcagcttt ttcgacgtgt ggcgtcggct      900

ctacccggaa tggagaatgt ccaggagaaa agcaaagaag ggatgatcga catcaagctg      960

gacaaacccc aggagccccc ggccagcgag ggcggctgct cctgctaatg cagagccgac     1020

ctgtggcttc ccatgacact ccttgcttgt tgtgttgctt cctattggct agcttcctaa     1080

ggggggaggg aaccgagtta tcaagatggg aggatttttc ttttctctct gtctttagga     1140

gtagggtggg atggggaggg aggctgggca tcagggatca catcactctt aacggctgtt     1200

acttaaacaa ctattttttg gtttggttgt aatatattgt actttattaa gattgccaaa     1260

aactgttaaa atttaaaaaa aatttaaatc atgtgtatac aattttttgc cagataaaaa     1320

tgtagtcatt tttatttgaa agatgtgctt tttgtttttg tatatttgta aacttataga     1380

gaaccttttc cacacacctc ctccttcctg ttctctttga accattcatc acctctgcct     1440

tcctcctatc cccagcccaa taaattaaaa caattaactg agcaaattaa ttaggcttca     1500

gtctggggcc atctggcccc actctctagg ccctactcca gttaaatcaa acattggttg     1560

aacacatcag cctctgaaaa ggtagctctg actcttgtct ttccatggcc agagtgggtc     1620

gtcaacctcg tgtggagctg agaccaaggt ctgtgggctc taggcagccc ggcagcagcc     1680

cccagaggaa ctgctcccac ctctccttct ctttccctga aaagccttga agggggttga     1740

gggtacaggc aaccttgtgt tctctgtgcc ctcagggact ggcagagcaa gaggccatca     1800

gaaggacgag gtgctgttgg caattgcagc tgcgtggtgc gtggtttata gactggggtg     1860

ccatgtgtac ttctgaaaat attttaacca gcccacccag cagtcagtac acatgcctgg     1920

gccaagtcta agaaactcag tgtgtgatgt tgggcagtgt gccatcctga agccttcctc     1980

ctggatgtca gggaagctgg accacctgga gttgatcctc tgtgatgggg aggcgggggg     2040

gggggggggt gttgtctgca gaaccaccac cttgaaagat ccatgttctt agagcctcag     2100

ctgctaatat tgttgagtgc tttctggaaa agctgatttg ttgctatgtt ttcaccccag     2160

tggcatggcg cagttgaagt ctttgtggac atatctttgt ggctactgtg gctgcgctgt     2220

ggtcacctga ggatgtggtt caggtggggt ctccagaagg ctgcttgccc ccagagagcc     2280

atctcttcca tttttgattc attcctgaga atggcttagt cctgagaatc tgcaaagtct     2340

ctgaagagaa ctctctcttc ccactaagtg atataaccta cttggccagc attccaaata     2400

gactcagact cactgccctg agcctgcaca gagccaggtg caatgggcag tgagtctggc     2460

caaaatgtaa accccaccct ccctgctgtc attggctctc cctccaggct gctgctgggc     2520

atgtcataga tgggatgaat gaccatctgg ggtatggtgg gctgaactcc acaaggtcgt     2580

tggaatgaat tttgaaactt ctcagaaatt aatctgaaat ggcaggcagt aagtgcagca     2640

gaatctggca ggactgatat ttgtgcagtg ggcctgccac acaccctctg cctaggaggc     2700

tgtatgccag agctcatctc tagcaaggaa tttatcttca ggtgaagaag agaggaagca     2760

ggatcccact gagcacctct tgcagaaggc aaggaccaat gtttgaacgt gtttcagatg     2820

tcatgtgttt agtttttata tgtgtgtaca taattatata tagagataga cttgtgtata     2880

caccttccac aaacacatcc tcacggagat acatgtgctc aatgtatatt cttgtttctc     2940

ctgctctcaa gttggaactt gcattgtgat aagttttgga aattcaaaag tactgcaacg     3000

tgttgaaata agaaatactt aatattgtca aataacttgt gattgtcttg ccatcaataa     3060

aataatgcat agttgtgtta aactacaggc aaacatagcc cacgggaata tctccaccat     3120

ttctctatgt actttatatg cacgggtgtg catgcctgtg tgggccagtg tccccccacc     3180

atgggcacac ccccaagtgg tgcttgttgg aagagtgctt acttacctcg agagaattta     3240

caggagtcca catgacagtg tcctgcctgg ttggcagcgg gggccatcac ctgtggcctc     3300

tgagaccgcc ccatttacag gaatctgcac tgggtctcag tgaatgaacg tatggtagat     3360

ttttattttc ttggcactaa agattagctt ttttaaaaaa acatcccata aaacagtaga     3420

aactcagttc ccttctcagg ggcacacaca tccaaggcac cgtggactgt gtttccatcc     3480

tggcctagag gagcagtaaa agatagcatt tggtttgaca tggccttagt gagtcctgcc     3540

tttcctagca tgcacacaac atcctctctt tgagtttggg ttctccccag ccccttggcc     3600

tctgaggctg agggtggctt cctcccatcc tcccatctca gtggttccat ggcgctccct     3660

tcggcacgtg cggtttccgc ccctcccttc ctggggtgtg gaaaggcagc cagacctctt     3720

tttcagaagt tgttggttcc ctgatttttg tcttgagcag gcaccatccc tgtccccttg     3780

cttgcaggta gaattggcac agagttaagg ttccataata aactgttagg tgctcttgaa     3840

gaagatgtca tggcattgcc tcagcacccc agcaagagca ttgcatcttt gctgaatcca     3900

gatgggttag cagagggcaa attggaggat tcctttgagg aaatgttctc aattgagcaa     3960

ttcagtccct ctccccaaag actagacgtg acctggcaga ttagcaggat cctcttggcc     4020

ttcttttttg gggatggtgg gagtgaaggg ggtgaatctt aaaagcttat caacaaagct     4080

cctgttctgc aggcatcagg aaagttgagt gtaagatgga aaaagcaaac agcctattta     4140

caagtggaaa cacattggtt ctgatcactc ctaacttgct gggtgatcat acatacatca     4200

acatgaaggt gtgacatcag aatcatgagc accatggctg cagttgtgtg atccaaggct     4260

agttggcttg gtagctgttg gcagcagttt cccttggtca gaggcctcct tgctatctat     4320

cgctgctctc ttcttgtcat ccttaaacat tcagtcatgt tcccaggtct gaggggagca     4380

atggccagac cagtttcagt atctctggca acagaaacaa ggattgaaat ggtggtagtt     4440

aagagtgcag acacatctgg ggtgcaacgt ctgcatcatc ctggtggcta gccagtgcgg     4500

ggaggccctg ccctgggata ccagttgtga caataaaggg atggccctcc tggcttcagc     4560

atcctgcagg tagagcagcc tcattccttc acaagatgga aggcaggtga ggatgtcagg     4620

atgagatggg accaggtagc cgaggacagt gaggcatgtc tgagccactt gaggggcagc     4680

tgaacagaag gatgtctgtg tgcatcaacc gagcagattg tgcgcacact cgtttccgaa     4740

ctgcctctcc ccaaagaatg tgaggcattg tcaccttgtt acagctatgt gaagcagagc     4800

tgtcacaact tttcctgtct acaggcagga aaaccaggat ggagaagggc aacttgctta     4860

ttaagatcac ccagcaagtt aggagtgatc agaaccagtg aagtttccat ttttcatcca     4920

ttgctgccct gtgtgtgaac aaatgtgact ccatatttat tacacagcaa ggactgctgt     4980

gtgtgggtgt gttcctcaga ccatctctac tctttttggt taggacacta ggttcttccc     5040

agcatatgag tgagaatatt ggtggtattt tgggctcctc tactgcacaa gggccagtcc     5100

ccaagtctac tctgattgat tgtcatgggc acccacacag atcaggacac cctttgaatt     5160

tttgtttgac atgaactatt taggtgttcc aaaaccttgg gatctcaatg tgcaaactcc     5220

ttggactcca gacccctgtc tggttggcac tcccagcagt gtgtggtttc atcaggaaat     5280

ccttgcagca ggggtttaga tggttccttc aggaggtggg aagcctccat agcattgaag     5340

gccagcctgc atctcgcggt gtgtgtccac ttctcccctc actttcccct cacccatccc     5400

tttaaagtga ttggctgtga ggagcacaga gggtggcaat tccatctgtt atgggctcag     5460

aagacatagc cgccatgttg atttcacatt aaactgtgta aaatgtggaa aagactcagc     5520

atgttggtca aacaataaac tgtcctaatt ctcaaaacaa a                         5561


<210>  211
<211>  10848
<212>  DNA
<213>  homo sapiens

<400>  211
gtattggtgc agcccgccag ggtgtcactg gagacagaat ggaggtgctg ccggactcgg       60

aaatggggac acatgcattg gtggccaaaa gagagaggag acaaaaccgc tgcagatggc      120

tgatgtgaat ctagtggaaa gagctactgg ggatgagaga aagaggagga ggcaggtcca      180

agggtagcca aggatggctg cagcttcata tgatcagttg ttaaagcaag ttgaggcact      240

gaagatggag aactcaaatc ttcgacaaga gctagaagat aattccaatc atcttacaaa      300

actggaaact gaggcatcta atatgaagga agtacttaaa caactacaag gaagtattga      360

agatgaagct atggcttctt ctggacagat tgatttatta gagcgtctta aagagcttaa      420

cttagatagc agtaatttcc ctggagtaaa actgcggtca aaaatgtccc tccgttctta      480

tggaagccgg gaaggatctg tatcaagccg ttctggagag tgcagtcctg ttcctatggg      540

ttcatttcca agaagagggt ttgtaaatgg aagcagagaa agtactggat atttagaaga      600

acttgagaaa gagaggtcat tgcttcttgc tgatcttgac aaagaagaaa aggaaaaaga      660

ctggtattac gctcaacttc agaatctcac taaaagaata gatagtcttc ctttaactga      720

aaatttttcc ttacaaacag atatgaccag aaggcaattg gaatatgaag caaggcaaat      780

cagagttgcg atggaagaac aactaggtac ctgccaggat atggaaaaac gagcacagcg      840

aagaatagcc agaattcagc aaatcgaaaa ggacatactt cgtatacgac agcttttaca      900

gtcccaagca acagaagcag agaggtcatc tcagaacaag catgaaaccg gctcacatga      960

tgctgagcgg cagaatgaag gtcaaggagt gggagaaatc aacatggcaa cttctggtaa     1020

tggtcagggt tcaactacac gaatggacca tgaaacagcc agtgttttga gttctagtag     1080

cacacactct gcacctcgaa ggctgacaag tcatctggga accaaggtgg aaatggtgta     1140

ttcattgttg tcaatgcttg gtactcatga taaggatgat atgtcgcgaa ctttgctagc     1200

tatgtctagc tcccaagaca gctgtatatc catgcgacag tctggatgtc ttcctctcct     1260

catccagctt ttacatggca atgacaaaga ctctgtattg ttgggaaatt cccggggcag     1320

taaagaggct cgggccaggg ccagtgcagc actccacaac atcattcact cacagcctga     1380

tgacaagaga ggcaggcgtg aaatccgagt ccttcatctt ttggaacaga tacgcgctta     1440

ctgtgaaacc tgttgggagt ggcaggaagc tcatgaacca ggcatggacc aggacaaaaa     1500

tccaatgcca gctcctgttg aacatcagat ctgtcctgct gtgtgtgttc taatgaaact     1560

ttcatttgat gaagagcata gacatgcaat gaatgaacta gggggactac aggccattgc     1620

agaattattg caagtggact gtgaaatgta tgggcttact aatgaccact acagtattac     1680

actaagacga tatgctggaa tggctttgac aaacttgact tttggagatg tagccaacaa     1740

ggctacgcta tgctctatga aaggctgcat gagagcactt gtggcccaac taaaatctga     1800

aagtgaagac ttacagcagg ttattgcgag tgttttgagg aatttgtctt ggcgagcaga     1860

tgtaaatagt aaaaagacgt tgcgagaagt tggaagtgtg aaagcattga tggaatgtgc     1920

tttagaagtt aaaaaggaat caaccctcaa aagcgtattg agtgccttat ggaatttgtc     1980

agcacattgc actgagaata aagctgatat atgtgctgta gatggtgcac ttgcattttt     2040

ggttggcact cttacttacc ggagccagac aaacacttta gccattattg aaagtggagg     2100

tgggatatta cggaatgtgt ccagcttgat agctacaaat gaggaccaca ggcaaatcct     2160

aagagagaac aactgtctac aaactttatt acaacactta aaatctcata gtttgacaat     2220

agtcagtaat gcatgtggaa ctttgtggaa tctctcagca agaaatccta aagaccagga     2280

agcattatgg gacatggggg cagttagcat gctcaagaac ctcattcatt caaagcacaa     2340

aatgattgct atgggaagtg ctgcagcttt aaggaatctc atggcaaata ggcctgcgaa     2400

gtacaaggat gccaatatta tgtctcctgg ctcaagcttg ccatctcttc atgttaggaa     2460

acaaaaagcc ctagaagcag aattagatgc tcagcactta tcagaaactt ttgacaatat     2520

agacaattta agtcccaagg catctcatcg tagtaagcag agacacaagc aaagtctcta     2580

tggtgattat gtttttgaca ccaatcgaca tgatgataat aggtcagaca attttaatac     2640

tggcaacatg actgtccttt caccatattt gaatactaca gtgttaccca gctcctcttc     2700

atcaagagga agcttagata gttctcgttc tgaaaaagat agaagtttgg agagagaacg     2760

cggaattggt ctaggcaact accatccagc aacagaaaat ccaggaactt cttcaaagcg     2820

aggtttgcag atctccacca ctgcagccca gattgccaaa gtcatggaag aagtgtcagc     2880

cattcatacc tctcaggaag acagaagttc tgggtctacc actgaattac attgtgtgac     2940

agatgagaga aatgcactta gaagaagctc tgctgcccat acacattcaa acacttacaa     3000

tttcactaag tcggaaaatt caaataggac atgttctatg ccttatgcca aattagaata     3060

caagagatct tcaaatgata gtttaaatag tgtcagtagt agtgatggtt atggtaaaag     3120

aggtcaaatg aaaccctcga ttgaatccta ttctgaagat gatgaaagta agttttgcag     3180

ttatggtcaa tacccagccg acctagccca taaaatacat agtgcaaatc atatggatga     3240

taatgatgga gaactagata caccaataaa ttatagtctt aaatattcag atgagcagtt     3300

gaactctgga aggcaaagtc cttcacagaa tgaaagatgg gcaagaccca aacacataat     3360

agaagatgaa ataaaacaaa gtgagcaaag acaatcaagg aatcaaagta caacttatcc     3420

tgtttatact gagagcactg atgataaaca cctcaagttc caaccacatt ttggacagca     3480

ggaatgtgtt tctccataca ggtcacgggg agccaatggt tcagaaacaa atcgagtggg     3540

ttctaatcat ggaattaatc aaaatgtaag ccagtctttg tgtcaagaag atgactatga     3600

agatgataag cctaccaatt atagtgaacg ttactctgaa gaagaacagc atgaagaaga     3660

agagagacca acaaattata gcataaaata taatgaagag aaacgtcatg tggatcagcc     3720

tattgattat agtttaaaat atgccacaga tattccttca tcacagaaac agtcattttc     3780

attctcaaag agttcatctg gacaaagcag taaaaccgaa catatgtctt caagcagtga     3840

gaatacgtcc acaccttcat ctaatgccaa gaggcagaat cagctccatc caagttctgc     3900

acagagtaga agtggtcagc ctcaaaaggc tgccacttgc aaagtttctt ctattaacca     3960

agaaacaata cagacttatt gtgtagaaga tactccaata tgtttttcaa gatgtagttc     4020

attatcatct ttgtcatcag ctgaagatga aataggatgt aatcagacga cacaggaagc     4080

agattctgct aataccctgc aaatagcaga aataaaagaa aagattggaa ctaggtcagc     4140

tgaagatcct gtgagcgaag ttccagcagt gtcacagcac cctagaacca aatccagcag     4200

actgcagggt tctagtttat cttcagaatc agccaggcac aaagctgttg aattttcttc     4260

aggagcgaaa tctccctcca aaagtggtgc tcagacaccc aaaagtccac ctgaacacta     4320

tgttcaggag accccactca tgtttagcag atgtacttct gtcagttcac ttgatagttt     4380

tgagagtcgt tcgattgcca gctccgttca gagtgaacca tgcagtggaa tggtaagtgg     4440

cattataagc cccagtgatc ttccagatag ccctggacaa accatgccac caagcagaag     4500

taaaacacct ccaccacctc ctcaaacagc tcaaaccaag cgagaagtac ctaaaaataa     4560

agcacctact gctgaaaaga gagagagtgg acctaagcaa gctgcagtaa atgctgcagt     4620

tcagagggtc caggttcttc cagatgctga tactttatta cattttgcca cggaaagtac     4680

tccagatgga ttttcttgtt catccagcct gagtgctctg agcctcgatg agccatttat     4740

acagaaagat gtggaattaa gaataatgcc tccagttcag gaaaatgaca atgggaatga     4800

aacagaatca gagcagccta aagaatcaaa tgaaaaccaa gagaaagagg cagaaaaaac     4860

tattgattct gaaaaggacc tattagatga ttcagatgat gatgatattg aaatactaga     4920

agaatgtatt atttctgcca tgccaacaaa gtcatcacgt aaagcaaaaa agccagccca     4980

gactgcttca aaattacctc cacctgtggc aaggaaacca agtcagctgc ctgtgtacaa     5040

acttctacca tcacaaaaca ggttgcaacc ccaaaagcat gttagtttta caccggggga     5100

tgatatgcca cgggtgtatt gtgttgaagg gacacctata aacttttcca cagctacatc     5160

tctaagtgat ctaacaatcg aatcccctcc aaatgagtta gctgctggag aaggagttag     5220

aggaggggca cagtcaggtg aatttgaaaa acgagatacc attcctacag aaggcagaag     5280

tacagatgag gctcaaggag gaaaaacctc atctgtaacc atacctgaat tggatgacaa     5340

taaagcagag gaaggtgata ttcttgcaga atgcattaat tctgctatgc ccaaagggaa     5400

aagtcacaag cctttccgtg tgaaaaagat aatggaccag gtccagcaag catctgcgtc     5460

ttcttctgca cccaacaaaa atcagttaga tggtaagaaa aagaaaccaa cttcaccagt     5520

aaaacctata ccacaaaata ctgaatatag gacacgtgta agaaaaaatg cagactcaaa     5580

aaataattta aatgctgaga gagttttctc agacaacaaa gattcaaaga aacagaattt     5640

gaaaaataat tccaaggtct tcaatgataa gctcccaaat aatgaagata gagtcagagg     5700

aagttttgct tttgattcac ctcatcatta cacgcctatt gaaggaactc cttactgttt     5760

ttcacgaaat gattctttga gttctctaga ttttgatgat gatgatgttg acctttccag     5820

ggaaaaggct gaattaagaa aggcaaaaga aaataaggaa tcagaggcta aagttaccag     5880

ccacacagaa ctaacctcca accaacaatc agctaataag acacaagcta ttgcaaagca     5940

gccaataaat cgaggtcagc ctaaacccat acttcagaaa caatccactt ttccccagtc     6000

atccaaagac ataccagaca gaggggcagc aactgatgaa aagttacaga attttgctat     6060

tgaaaatact ccggtttgct tttctcataa ttcctctctg agttctctca gtgacattga     6120

ccaagaaaac aacaataaag aaaatgaacc tatcaaagag actgagcccc ctgactcaca     6180

gggagaacca agtaaacctc aagcatcagg ctatgctcct aaatcatttc atgttgaaga     6240

taccccagtt tgtttctcaa gaaacagttc tctcagttct cttagtattg actctgaaga     6300

tgacctgttg caggaatgta taagctccgc aatgccaaaa aagaaaaagc cttcaagact     6360

caagggtgat aatgaaaaac atagtcccag aaatatgggt ggcatattag gtgaagatct     6420

gacacttgat ttgaaagata tacagagacc agattcagaa catggtctat cccctgattc     6480

agaaaatttt gattggaaag ctattcagga aggtgcaaat tccatagtaa gtagtttaca     6540

tcaagctgct gctgctgcat gtttatctag acaagcttcg tctgattcag attccatcct     6600

ttccctgaaa tcaggaatct ctctgggatc accatttcat cttacacctg atcaagaaga     6660

aaaacccttt acaagtaata aaggcccacg aattctaaaa ccaggggaga aaagtacatt     6720

ggaaactaaa aagatagaat ctgaaagtaa aggaatcaaa ggaggaaaaa aagtttataa     6780

aagtttgatt actggaaaag ttcgatctaa ttcagaaatt tcaggccaaa tgaaacagcc     6840

ccttcaagca aacatgcctt caatctctcg aggcaggaca atgattcata ttccaggagt     6900

tcgaaatagc tcctcaagta caagtcctgt ttctaaaaaa ggcccacccc ttaagactcc     6960

agcctccaaa agccctagtg aaggtcaaac agccaccact tctcctagag gagccaagcc     7020

atctgtgaaa tcagaattaa gccctgttgc caggcagaca tcccaaatag gtgggtcaag     7080

taaagcacct tctagatcag gatctagaga ttcgacccct tcaagacctg cccagcaacc     7140

attaagtaga cctatacagt ctcctggccg aaactcaatt tcccctggta gaaatggaat     7200

aagtcctcct aacaaattat ctcaacttcc aaggacatca tcccctagta ctgcttcaac     7260

taagtcctca ggttctggaa aaatgtcata tacatctcca ggtagacaga tgagccaaca     7320

gaaccttacc aaacaaacag gtttatccaa gaatgccagt agtattccaa gaagtgagtc     7380

tgcctccaaa ggactaaatc agatgaataa tggtaatgga gccaataaaa aggtagaact     7440

ttctagaatg tcttcaacta aatcaagtgg aagtgaatct gatagatcag aaagacctgt     7500

attagtacgc cagtcaactt tcatcaaaga agctccaagc ccaaccttaa gaagaaaatt     7560

ggaggaatct gcttcatttg aatctctttc tccatcatct agaccagctt ctcccactag     7620

gtcccaggca caaactccag ttttaagtcc ttcccttcct gatatgtctc tatccacaca     7680

ttcgtctgtt caggctggtg gatggcgaaa actcccacct aatctcagtc ccactataga     7740

gtataatgat ggaagaccag caaagcgcca tgatattgca cggtctcatt ctgaaagtcc     7800

ttctagactt ccaatcaata ggtcaggaac ctggaaacgt gagcacagca aacattcatc     7860

atcccttcct cgagtaagca cttggagaag aactggaagt tcatcttcaa ttctttctgc     7920

ttcatcagaa tccagtgaaa aagcaaaaag tgaggatgaa aaacatgtga actctatttc     7980

aggaaccaaa caaagtaaag aaaaccaagt atccgcaaaa ggaacatgga gaaaaataaa     8040

agaaaatgaa ttttctccca caaatagtac ttctcagacc gtttcctcag gtgctacaaa     8100

tggtgctgaa tcaaagactc taatttatca aatggcacct gctgtttcta aaacagagga     8160

tgtttgggtg agaattgagg actgtcccat taacaatcct agatctggaa gatctcccac     8220

aggtaatact cccccggtga ttgacagtgt ttcagaaaag gcaaatccaa acattaaaga     8280

ttcaaaagat aatcaggcaa aacaaaatgt gggtaatggc agtgttccca tgcgtaccgt     8340

gggtttggaa aatcgcctga actcctttat tcaggtggat gcccctgacc aaaaaggaac     8400

tgagataaaa ccaggacaaa ataatcctgt ccctgtatca gagactaatg aaagttctat     8460

agtggaacgt accccattca gttctagcag ctcaagcaaa cacagttcac ctagtgggac     8520

tgttgctgcc agagtgactc cttttaatta caacccaagc cctaggaaaa gcagcgcaga     8580

tagcacttca gctcggccat ctcagatccc aactccagtg aataacaaca caaagaagcg     8640

agattccaaa actgacagca cagaatccag tggaacccaa agtcctaagc gccattctgg     8700

gtcttacctt gtgacatctg tttaaaagag aggaagaatg aaactaagaa aattctatgt     8760

taattacaac tgctatatag acattttgtt tcaaatgaaa ctttaaaaga ctgaaaaatt     8820

ttgtaaatag gtttgattct tgttagaggg tttttgttct ggaagccata tttgatagta     8880

tactttgtct tcactggtct tattttggga ggcactcttg atggttagga aaaaaatagt     8940

aaagccaagt atgtttgtac agtatgtttt acatgtattt aaagtagcat cccatcccaa     9000

cttcctttaa ttattgcttg tcttaaaata atgaacacta cagatagaaa atatgatata     9060

ttgctgttat caatcatttc tagattataa actgactaaa cttacatcag ggaaaaattg     9120

gtatttatgc aaaaaaaaat gtttttgtcc ttgtgagtcc atctaacatc ataattaatc     9180

atgtggctgt gaaattcaca gtaatatggt tcccgatgaa caagtttacc cagcctgctt     9240

tgctttactg catgaatgaa actgatggtt caatttcaga agtaatgatt aacagttatg     9300

tggtcacatg atgtgcatag agatagctac agtgtaataa tttacactat tttgtgctcc     9360

aaacaaaaca aaaatctgtg taactgtaaa acattgaatg aaactatttt acctgaacta     9420

gattttatct gaaagtaggt agaatttttg ctatgctgta atttgttgta tattctggta     9480

tttgaggtga gatggctgct cttttattaa tgagacatga attgtgtctc aacagaaact     9540

aaatgaacat ttcagaataa attattgctg tatgtaaact gttactgaaa ttggtatttg     9600

tttgaagggt cttgtttcac atttgtatta ataattgttt aaaatgcctc ttttaaaagc     9660

ttatataaat ttttttcttc agcttctatg cattaagagt aaaattcctc ttactgtaat     9720

aaaaacaatt gaagaagact gttgccactt aaccattcca tgcgttggca cttatctatt     9780

cctgaaattt cttttatgtg attagctcat cttgattttt aatatttttc cacttaaact     9840

tttttttctt actccactgg agctcagtaa aagtaaattc atgtaatagc aatgcaagca     9900

gcctagcaca gactaagcat tgagcataat aggcccacat aatttcctct ttcttaatat     9960

tatagaattc tgtacttgaa attgattctt agacattgca gtctcttcga ggctttacag    10020

tgtaaactgt cttgcccctt catcttcttg ttgcaactgg gtctgacatg aacacttttt    10080

atcaccctgt atgttagggc aagatctcag cagtgaagta taatcagcac tttgccatgc    10140

tcagaaaatt caaatcacat ggaactttag aggtagattt aatacgatta agatattcag    10200

aagtatattt tagaatccct gcctgttaag gaaactttat ttgtggtagg tacagttctg    10260

gggtacatgt taagtgtccc cttatacagt ggagggaagt cttccttcct gaaggaaaat    10320

aaactgacac ttattaacta agataattta cttaatatat cttccctgat ttgttttaaa    10380

agatcagagg gtgactgatg atacatgcat acatatttgt tgaataaatg aaaatttatt    10440

tttagtgata agattcatac actctgtatt tggggaggga aaaccttttt aagcatggtg    10500

gggcactcag ataggagtga atacacctac ctggtgcctt gaaaatcaca tcaagtagtt    10560

aattatctac cccttacctg tgtttataac ttccaggtaa tgagaatgat tttttttaaa    10620

gctaaaatgc cagtaaataa aagtgctatg acttgagcta agatatttga ctccaatgcc    10680

tgtactgtgt ctactgcacc actttgtaaa cacttcaatt tactatcttt gaaatgattg    10740

acctttaaat ttttgccaaa tgttatctga aattgtctat gaataccatc tacttctgtt    10800

gttttcccag gcttccataa acaatggaga tacatgcaaa aaaaaaaa                 10848


<210>  212
<211>  2689
<212>  DNA
<213>  homo sapiens

<400>  212
atcccagtgg gtggcagctg gaggcggggc accctgaggg gcggggaagg actagggtgc       60

ggggaggggg ttgcaaaagg agccgagcgg cttctgctca atggcggaaa agccgccggt      120

gctctgacgg cctcgttccc ctagcagttg cgggggagtt tcctgccggc gcggctggag      180

tctctgattc tcagggttcg gtggttggaa gatgctccag agagacgagg ctgcggcgga      240

ggaggtggcg gcggccgaat cggcaacggc gctagggtgg agagaaggcg gcatcggcgg      300

cggcggcggc gtgaggggcc gggcggtgta aacagccccg gaggcggcgg tcgagacccc      360

gagggggaag cggcggctga gtcagggtcg cgcctccgtt ggaaacttgg gctgagtacc      420

gcggcgggcg cgagcgaggc gccctagaca tcttctccct cccttgcctc agatttattg      480

ctaaacatgg gtgcattttt ggataaaccc aaaactgaaa aacataatgc tcatggtgct      540

gggaatggtt tacgttatgg cctgagcagc atgcaaggat ggagagtgga aatggaagat      600

gcacacacag ctgttgtagg tattcctcac ggcttggaag actggtcatt ttttgcagtt      660

tatgatggtc atgctggatc ccgagtggca aattactgct caacacattt attagaacac      720

atcactacta acgaagactt tagggcagct ggaaaatcag gatctgctct tgagctttca      780

gtggaaaatg ttaagaatgg tatcagaact ggatttttga aaattgatga atacatgcgt      840

aacttttcag acctcagaaa cgggatggac aggagtggtt caactgcagt gggagttatg      900

atttcaccta agcatatcta ctttatcaac tgtggtgatt cacgtgctgt tctgtatagg      960

aatggacaag tctgcttttc tacccaggat cacaaacctt gcaatccaag ggaaaaggag     1020

cgaatccaaa atgcaggagg cagcgtgatg atacaacgtg ttaatggttc attagcagta     1080

tctcgtgctc tgggggacta tgattacaag tgtgttgatg gcaagggccc aacagaacaa     1140

cttgtttctc cagagcctga ggtttatgaa attttaagag cagaagagga tgaatttatc     1200

atcttggctt gtgatgggat ctgggatgtt atgagtaatg aggagctctg tgaatatgtt     1260

aaatctaggc ttgaggtatc tgatgacctg gaaaatgtgt gcaattgggt agtggacact     1320

tgtttacaca agggaagtcg agataacatg agtattgtac tagtttgctt ttcaaatgct     1380

cccaaggtct cagatgaagc ggtgaaaaaa gattcagagt tggataagca cttggaatca     1440

cgggttgaag agattatgga gaagtctggc gaggaaggaa tgcctgatct tgcccatgtc     1500

atgcgcatct tgtctgcaga aaatatccca aatttgcctc ctgggggagg tcttgctggc     1560

aagcgtaatg ttattgaagc tgtttatagt agactgaatc cacatagaga aagtgatggg     1620

gcctccgatg aagcagagga aagtggatca cagggaaaat tggtggaagc tctcaggcaa     1680

atgagaatta atcatagggg aaactaccga caacttctgg aggagatgct gactagttac     1740

aggctagcta aagtagaggg agaagaaagc cctgctgaac cagctgccac agctacttct     1800

tcgaacagtg atgctggaaa cccagtgaca atgcaggaaa gccatactga atcagaaagt     1860

ggtcttgctg aattagacag ctctaatgaa gatgcaggga caaagatgag tggtgaaaaa     1920

atatgacttt cctttttggt aatatttttg tgatctttga tggtttttaa cctaggaagt     1980

gtaatgtatg catttatata actgttttgt tatttgaatc ttggaaaact agttttatta     2040

tattcagata gccttgtttt ttaaaaaggc ctttgcatac acctttatga gatagtgtaa     2100

aattgactat ttatagtact atggatttaa tgaaattata tgtcatttca cattgtatgc     2160

cagaaattag gctaccaatt atgaattaaa gtcagtagtt aaattaatac tagatagaat     2220

tagaaatttt gattagagag attatgctat attatggaaa aacttgttaa tgtagaatta     2280

tactgcttca tattatttta cctattagta cactcatagt tagctttgta ataaatttat     2340

gttttcttta ataattttag ttcttcaaag aatggctgat gctggcctgt aatttttctt     2400

tcaaggatga taatttgtgt gttgtttgat ttgtttatat tttacatctc tgtagtttta     2460

tttttagaag ttgtgagata ttggatgtgt ggctattttt cctttctctg tattctttat     2520

gaaacataac ttttgaaaaa cctatgtatt attcatacag ctttggtttg tatattctgt     2580

atagcctaac tacacacatc aaaatgtatg tcaaccaagt gtttagaatg aaattataag     2640

tgtttaagtc caaataaagc atgtgatgtg gaataatcta taaaaaaaa                 2689


<210>  213
<211>  8318
<212>  DNA
<213>  homo sapiens

<400>  213
gccatttcca gagaggaaca accgtgtaga ctgctttcct gggagtcaag ttaaaacttc       60

tctcctgtga ccttgtcacc cggcagtgga aagttaccct tggctgcagc cacgacttcc      120

gcatactctt cagaacttgc tctgcccttg agttttccag ctttccttta atgcactaaa      180

cctttaatat tgtattctcc taaatgagac gtctcgcatt tgagcaggga gagtcccgta      240

ttctcagagt aaaagttgtt tctggaattg atctcgccaa aaaggacatc tttggagcca      300

gtgatccgta tgtgaaactt tcattgtacg tagcggatga gaatagagaa cttgctttgg      360

tccagacaaa aacaattaaa aagacactga acccaaaatg gaatgaagaa ttttatttca      420

gggtaaaccc atctaatcac agactcctat ttgaagtatt tgacgaaaat agactgacac      480

gagacgactt cctgggccag gtggacgtgc cccttagtca ccttccgaca gaagatccaa      540

ccatggagcg accctataca tttaaggact ttctcctcag accaagaagt cataagtctc      600

gagttaaggg atttttgcga ttgaaaatgg cctatatgcc aaaaaatgga ggtcaagatg      660

aagaaaacag tgaccagagg gatgacatgg agcatggatg ggaagttgtt gactcaaatg      720

actcggcttc tcagcaccaa gaggaacttc ctcctcctcc tctgcctccc gggtgggaag      780

aaaaagtgga caatttaggc cgaacttact atgtcaacca caacaaccgg accactcagt      840

ggcacagacc aagcctgatg gacgtgtcct cggagtcgga caataacatc agacagatca      900

accaggaggc agcacaccgg cgcttccgct cccgcaggca catcagcgaa gacttggagc      960

ccgagccctc ggagggcggg gatgtccccg agccttggga gaccatttca gaggaagtga     1020

atatcgctgg agactctctc ggtctggctc tgcccccacc accggcctcc ccaggatctc     1080

ggaccagccc tcaggagctg tcagaggaac taagcagaag gcttcagatc actccagact     1140

ccaatgggga acagttcagc tctttgattc aaagagaacc ctcctcaagg ttgaggtcat     1200

gcagtgtcac cgacgcagtt gcagaacagg gccatctacc accgccatca gtggcctatg     1260

tacataccac gccgggtctg ccttcaggct gggaagaaag aaaagatgct aaggggcgca     1320

catactatgt caatcataac aatcgaacca caacttggac tcgacctatc atgcagcttg     1380

cagaagatgg tgcgtccgga tcagccacaa acagtaacaa ccatctaatc gagcctcaga     1440

tccgccggcc tcgtagcctc agctcgccaa cagtaacttt atctgccccg ctggagggtg     1500

ccaaggactc acccgtacgt cgggctgtga aagacaccct ttccaaccca cagtccccac     1560

agccatcacc ttacaactcc cccaaaccac aacacaaagt cacacagagc ttcttgccac     1620

ccggctggga aatgaggata gcgccaaacg gccggccctt cttcattgat cataacacaa     1680

agactacaac ctgggaagat ccacgtttga aatttccagt acatatgcgg tcaaagacat     1740

ctttaaaccc caatgacctt ggcccccttc ctcctggctg ggaagaaaga attcacttgg     1800

atggccgaac gttttatatt gatcataata gcaaaattac tcagtgggaa gacccaagac     1860

tgcagaaccc agctattact ggtccggctg tcccttactc cagagaattt aagcagaaat     1920

atgactactt caggaagaaa ttaaagaaac ctgctgatat ccccaatagg tttgaaatga     1980

aacttcacag aaataacata tttgaagagt cctatcggag aattatgtcc gtgaaaagac     2040

cagatgtcct aaaagctaga ctgtggattg agtttgaatc agagaaaggt cttgactatg     2100

ggggtgtggc cagagaatgg ttcttcttac tgtccaaaga gatgttcaac ccctactacg     2160

gcctctttga gtactctgcc acggacaact acacccttca gatcaaccct aattcaggcc     2220

tctgtaatga ggatcatttg tcctacttca cttttattgg aagagttgct ggtctggccg     2280

tatttcatgg gaagctctta gatggtttct tcattagacc attttacaag atgatgttgg     2340

gaaagcagat aaccctgaat gacatggaat ctgtggatag tgaatattac aactctttga     2400

aatggatcct ggagaatgac cctactgagc tggacctcat gttctgcata gacgaagaaa     2460

actttggaca gacatatcaa gtggatttga agcccaatgg gtcagaaata atggtcacaa     2520

atgaaaacaa aagggaatat atcgacttag tcatccagtg gagatttgtg aacagggtcc     2580

agaagcagat gaacgccttc ttggagggat tcacagaact acttcctatt gatttgatta     2640

aaatttttga tgaaaatgag ctggagttgc tcatgtgcgg cctcggtgat gtggatgtga     2700

atgactggag acagcattct atttacaaga acggctactg cccaaaccac cccgtcattc     2760

agtggttctg gaaggctgtg ctactcatgg acgccgaaaa gcgtatccgg ttactgcagt     2820

ttgtcacagg gacatcgcga gtacctatga atggatttgc cgaactttat ggttccaatg     2880

gtcctcagct gtttacaata gagcaatggg gcagtcctga gaaactgccc agagctcaca     2940

catgctttaa tcgccttgac ttacctccat atgaaacctt tgaagattta cgagagaaac     3000

ttctcatggc cgtggaaaat gctcaaggat ttgaaggggt ggattaagca ccctgtgcct     3060

cgggggtggt tgttcttcaa gcaagttctg cttgcacttt tgcatttgcc taacagactt     3120

ttgcagaggc gatggcagag agcagctgca ggcatggtcc ctggagccga gccttcacca     3180

cgcactcgtc caagttcgga tgcgggaacc tggtcccagc ttgagttcct gcctttccca     3240

ccacaaatta tcaactggtt gatgtgtaca ctaattacat ttcaggagga cttaatgcta     3300

tttatgttgt gcctctgcag gcaaagccct taataaatat tttacatcct ttctaatgac     3360

aatgaatgga attaatcact caacaggtat agtattacga ctcatgttta ctttttaaaa     3420

tgatttagac cgattttcag attttatttc gttatgatta aagatgtctc atgtacttgg     3480

aaaagtgagc attttttttt tttttgtatt tcactttcat accaggctta atgtcaatga     3540

catttttatt tttgaagtac tctgacacct ccaccctcta ctttattaga attggaaggc     3600

aaatttttgt ccaaaaacct acagacaagt actttgagag aatttccaat ataatattag     3660

acataatgat aattttttcc atactcagaa tgaaaaactg gatattacgt ttttgttttg     3720

gggttttttt gtacaaattt agctaatagc tacaggctga gagaattgta acatagcatg     3780

acaaattttg tgttgacttg aaaggaatca caccattatt ccttagaagt aattacatgt     3840

gttctaacac atttgagaca gggttggact cccatttctc atccgagaaa ttacttaacc     3900

cttcctggcg ctgtacagtc atcttttatt ctatttcctc tttgctgttt gtagtagaga     3960

cattttgaat gaaacttggc actgcttgat tcaaaactgt ggaaaccaga tctgtttagt     4020

ctcctgtttg tatgcgtttg ctaatggtag ctaaataacc agtttttgtt gtaaatgcac     4080

caattctgaa ggcactttat gtactacatg gaggtcatat ctggttttgt ttttattttt     4140

ttatcatgaa cattaaatgt gatgatgatt tcttttccct gcacacatct ttccggtgca     4200

atatctatca attgtgaatc tggctgctgg tgtataaaaa cctggatgta aagctgagcc     4260

tacagacctg tcctcaccaa ctgttttgtg atttctactc aactacaaag atttatttaa     4320

tgtactctta atctaactga gttttgttac caatgacctg ttgcatgctt caataccgtg     4380

tactgcctga gttgtgcctc ttgtgtgcta gattaaaagt gagacagaga cttgacttga     4440

tcctctgagc tcaagctatt gagctggtag tggcagagga ctgagggtac ctgcacagtt     4500

tgattctttt ccacgtgtaa gtctccattg cagaattgtc gtgctttgag aaaacacctg     4560

aggcagtgtg ggagttgaac gaccctgctg tcctttttaa cctgtgttgt cctagaccct     4620

gtcggggcag tcaggggaca ctagagattt gatctcatgc gagtcatcaa taggacaaaa     4680

aagttgtggt ttggggaggt ctgtttgtta cataaaaagg acctttcggt gtaagaaatt     4740

gccgttttta ccctgccctg gctggcatgt gagaagccat ggaaggttgt ggttgtaaat     4800

gagttgtcta aaggggtgca gaggcctgag gtttctaaaa gaaggtagat ttctacagag     4860

ctgagtgttg gttccttttt cttattggtt gaaaattacc tggtagtgat cagaaaactt     4920

agatgctatg taactaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aattcccgct     4980

catgagtttt gactattggt gagatgtttt ccgctacagt taacatgaca aatgtctcag     5040

tggcaaaaat cccctttttg taagccccca tagtctagag gcagttttct ttttaagaat     5100

catgccagag cctgagtcga gcagtatgct ttcttggttt ttgagagtaa ttgtgtaatt     5160

gtagagggag aaatccaatt ctaacctaag aactgggatt cttctgtcat cttgtaaacc     5220

gtatattgaa aaaaacagaa tgtcactaaa tgcatattaa gtcaagtatt ggaaagtata     5280

aaagaaaaat cattctgaca atttctaagc cagaagcaaa caagaattac tgaaatctac     5340

cccatgaata cttggaaggc agtaattgtg agtgacacct cagttcatca accccttaat     5400

aatatcagct taattttaat gacaactaaa tatgctgaag tgaggattta gtatttttta     5460

aaaaagcaaa acaaggttca gtagtcctca gcaattctcc aagtttctct ctttgcctaa     5520

aatggtcata gatcttgatt tctctgaatc gtgatgacca cacccagtca tcttcacagc     5580

ataattgcag gtggcagtaa agagagtgtg ctgggtaagg agcagttgct gggtcattcc     5640

ttgggccccg acctgcccgg ggagtagccc tgggggagag agggcagtgt tgcctatccc     5700

agaggtccca gcagtcacac tgctctgcag gccgggctct ctttatagcc agagaaatca     5760

ccttaatgca gtctctttag ttgtctgctg aagctgtagt tattatgggc cacttacatg     5820

aggctgagaa gtacgtgccg gagctcacac actgcctgtt gcggttctct taacatcagt     5880

tatcacagct gcctgtgggt cccgggtatt tccattcctg ccccttgttg gcccgaggaa     5940

ggatgtggaa agagcacctg gtgggatgaa ggtccaacag cctgtgcctc tccactgctg     6000

gccctggagc cggcagcagt gaggcattca ttgtctgtgt tgcggtgtat tcccagcttc     6060

agtgctcttt tcctttttgc ctgaaatgtt tatgcttctc tgcagccagt cctctaacaa     6120

atctcaagaa caaaggtaag acacttggtt tttgtttcca ggacccttca gaaggtgaca     6180

tcagatattc cctaaattca gacaatgagg gatacagagc gacttggcat gtattatttc     6240

tcccatgtaa ggacaaaggg acagattatt attgttattt ctgagacaga gtcttgctct     6300

gtagctcagg ctggagtgca gtggctcaat ctcagctcac cacaacctct gcctcctggc     6360

ttcaagcgat tcttctgcct cagcctcccc gaatagttgg gattacaggc acccaccacc     6420

acgcctggct aatttttgta tttttagtag agatggtttc accatgctgg ccaggctggt     6480

cttgaactcc tgacctcagg tgatcctccc gcctcagcct tccaaagtgc tgggattaca     6540

agcatgagcc accgcacccg gcctcacagt gacagattct gagaaacagc atgcaaaaca     6600

tttgaaccat tttctacatc tcccattgtt gcatagagag tgtgcaccgc tgctatcttg     6660

ccagatccac actggtcctc ccgaaagcca ggttcataca cagcaacttt ttaattattc     6720

taacagttac ccattaacag tcgactcctg tatttctgag agtcttgtac tcacctctga     6780

aatttaaaaa cgtataaaga gagcctgggt taatcagttc tgcagcccct acgtgacact     6840

gtgctagttc tccttcttct gtctcctcct taccctggcc ctgcacccct gtacttaaga     6900

gggagaggtg ggaggtgctg tctggtatca tttgctgcct cgccagtaga gggtgccgct     6960

gtgcagggta actgcccgcc tgctcccttc ctgacctccc ctgaccccga agatcactac     7020

ctctgtcatt caggcattgg ggtacatcct gataagtcgt gtcagaactg ccaatttcag     7080

gactgagatg tgtttttaaa aaacaaatcc ttataaactc cactttgtac tttagatttt     7140

aaaactgggg aaaaatgtga tattctttgg accacttttt taatttatat aagccttaat     7200

gaacagtgtc tatacatttg catacacaca cccccacccc agagtgttct cagtatgtca     7260

gagaaagtgc cacagcatta ggacgggagc ttggagaacg ttttctagaa aagggttagc     7320

ttcctgttgg catgaaattt tccaagcaaa cctcattaaa catctgttgt ttgttaaaga     7380

tgttccactg aaagcaacgc atgtttcaaa ggcacgtctt tccgttcgtt ggttttctgt     7440

gtgtaaggag tagcattgct gttggcgcct aacctcgcgt gcactgcatt ctcaaccccg     7500

taccagtgca tcatcagaag ccttcctcgt gaccataact ctgtgtctgc agatatgtgt     7560

tcccgtgtaa gccagttttc cccttttact cagactgatt tcacctagat tgtcacggtt     7620

tccttcatgt taactttgcg tgactttgtt cttcctttac tactctgtat gtaatatata     7680

tacatatata cgtacatatg ctgtccaaat atatttgtat atatttgtat agcattttta     7740

cacctttatt gagtaatctg gtttcgaaag gaggtgagag tttagtccct tctgcagttt     7800

tctccaagct gtgtcctgtg aatttcaacc cttggagcct aagaaaaccc taggaagatg     7860

atgttaattt gctgtcattt cctaattcag gatctatcat caaatgaaac atgaaaaaaa     7920

cagtgacttt taaggtgaaa agagtttcaa gcattccaaa taaattatca atgtttcata     7980

actttttatt ataaacccac ctcctaatag gaagccaagt actatttgat acagtggtaa     8040

aaaccaaact accttgaatt tttttaaggc aacttatgaa taatgctcat tttcacagtc     8100

agaatagctt taaaatatgg ttgaatttga tacacacagg aagttttctt gaagaacaat     8160

cctttcgctt ttcttttttc ttgagagatc taaagagaaa ctgtagattg ttttcctgac     8220

agcaaaagac taatgtgaca aaatgaagtc attgtaaaga agcgatgcaa cttgtcaaat     8280

atttaataaa gaattatgga agctggaaca ttttctac                             8318


<210>  214
<211>  2682
<212>  DNA
<213>  homo sapiens

<400>  214
ccccacccgc ttccggccgc ggctcggttc tcccgcctcc gcctccgccg cggctcgtgg       60

ttgtcccgcc atggcactgt cgcgggggct gccccgggag ctggctgagg cggtggccgg      120

gggccgggtg ctggtggtgg gggcgggcgg catcggctgc gagctcctca agaatctcgt      180

gctcaccggt ttctcccaca tcgacctgat tgatctggat actattgatg taagcaacct      240

caacagacag tttttgtttc aaaagaaaca tgttggaaga tcaaaggcac aggttgccaa      300

ggaaagtgta ctgcagtttt acccgaaagc taatatcgtt gcctaccatg acagcatcat      360

gaaccctgac tataatgtgg aatttttccg acagtttata ctggttatga atgctttaga      420

taacagagct gcccgaaacc atgttaatag aatgtgcctg gcagctgatg ttcctcttat      480

tgaaagtgga acagctgggt atcttggaca agtaactact atcaaaaagg gtgtgaccga      540

gtgttatgag tgtcatccta agccgaccca gagaaccttt cctggctgta caattcgtaa      600

cacaccttca gaacctatac attgcatcgt ttgggcaaag tacttgttca accagttgtt      660

tggggaagaa gatgctgatc aagaagtatc tcctgacaga gctgaccctg aagctgcctg      720

ggaaccaacg gaagccgaag ccagagctag agcatctaat gaagatggtg acattaaacg      780

tatttctact aaggaatggg ctaaatcaac tggatatgat ccagttaaac tttttaccaa      840

gctttttaaa gatgacatca ggtatctgtt gacaatggac aaactatggc ggaaaaggaa      900

acctccagtt ccgttggact gggctgaagt acaaagtcaa ggagaagaaa cgaatgcatc      960

agatcaacag aatgaacccc agttaggcct gaaagaccag caggttctag atgtaaagag     1020

ctatgcacgt cttttttcaa agagcatcga gactttgaga gttcatttag cagaaaaggg     1080

ggatggagct gagctcatat gggataagga tgacccatct gcaatggatt ttgtcacctc     1140

tgctgcaaac ctcaggatgc atattttcag tatgaatatg aagagtagat ttgatatcaa     1200

atcaatggca gggaacatta ttcctgctat tgctactact aatgcagtaa ttgctgggtt     1260

gatagtattg gaaggattga agattttatc aggaaaaata gaccagtgca gaacaatttt     1320

tttgaataaa caaccaaacc caagaaagaa gcttcttgtg ccttgtgcac tggatcctcc     1380

caaccccaat tgttatgtat gtgccagcaa gccagaggtg actgtgcggc tgaatgtcca     1440

taaagtgact gttctcacct tacaagacaa gatagtgaaa gaaaaatttg ctatggtagc     1500

accagatgtc caaattgaag atgggaaagg aacaatccta atatcttccg aagagggaga     1560

gacggaagct aataatcaca agaagttgtc agaatttgga attagaaatg gcagccggct     1620

tcaagcagat gacttcctcc aggactatac tttattgatc aacatccttc atagtgaaga     1680

cctaggaaag gacgttgaat ttgaagttgt tggtgatgcc ccggaaaaag tggggcccaa     1740

acaagctgaa gatgctgcca aaagcataac caatggcagt gatgatggag ctcagccctc     1800

cacctccaca gctcaagagc aagatgacgt tctcatagtt gattcagatg aagaagattc     1860

ttcaaataat gccgacgtca gtgaagaaga gagaagccgc aagaggaaat tagatgagaa     1920

agagaatctc agtgcaaaga ggtcacgtat agaacagaag gaagagcttg atgatgtcat     1980

agcattagat tgaacagaaa tgcctctaaa cagaaccctc ttactattta gtttatctgg     2040

gcagaaccag attgttatgt cctttgttcc aaagggaaaa aattgacagc agtgacttga     2100

aaatgattct gctccctttg aaagcattca ttttgctaga actgttagac acattgcagt     2160

atgctgtatt gaaagtagga atatagtttt aaaaaccctt tgaacaaagt gtgtgcataa     2220

ccagtcatga gataaaacaa cacaatgcat gttgcctttt taatgtaaat acccgtaggt     2280

atcattaata gtttcaaaat attgtggttt agtaaagttg atacctggtt ataaatatta     2340

tgcctttatt tttggctaga agaagaatta tttttagcct agatctaacc attttcatac     2400

tcttaactga ttgaaacaga ttcaaagaag tatcgagtgc tatgcattga aacttgtttt     2460

taaatgttag atggcactat gtatattaat gtaaaacaat gttaatttac tcaagttttc     2520

agtttgtacc gcctggtatg tctgtgtaag aagccaattt ttgtgtattg ttacagtttc     2580

aggttattta tattcgatgt tttgtaaaac tcaaataacg actatactta tggaccaaat     2640

aaatggcatc tgcattcttg ttacaaaaaa aaaaaaaaaa aa                        2682


<210>  215
<211>  2486
<212>  DNA
<213>  homo sapiens

<400>  215
gcactgcctc tggcacctgg ggcagccgcg cccgcggagt tttccgcccg gcgctgacgg       60

ctgctgcgcc cgcggctccc cagtgccccg agtgccccgc gggccccgcg agcgggagtg      120

ggacccagcc cctaggcaga acccaggcgc cgcgcccggg acgcccgcgg agagagccac      180

tcccgcccac gtcccatttc gcccctcgcg tccggagtcc ccgtggccag atctaaccat      240

gagctaccct ggctatcccc cgcccccagg tggctaccca ccagctgcac caggtggtgg      300

tccctgggga ggtgctgcct accctcctcc gcccagcatg ccccccatcg ggctggataa      360

cgtggccacc tatgcggggc agttcaacca ggactatctc tcgggaatgg cggccaacat      420

gtctgggaca tttggaggag ccaacatgcc caacctgtac cctggggccc ctggggctgg      480

ctacccacca gtgccccctg gcggctttgg gcagcccccc tctgcccagc agcctgttcc      540

tccctatggg atgtatccac ccccaggagg aaacccaccc tccaggatgc cctcatatcc      600

gccataccca ggggcccctg tgccgggcca gcccatgcca ccccccggac agcagccccc      660

aggggcctac cctgggcagc caccagtgac ctaccctggt cagcctccag tgccactccc      720

tgggcagcag cagccagtgc cgagctaccc aggatacccg gggtctggga ctgtcacccc      780

cgctgtgccc ccaacccagt ttggaagccg aggcaccatc actgatgctc ccggctttga      840

ccccctgcga gatgccgagg tcctgcggaa ggccatgaaa ggcttcggga cggatgagca      900

ggccatcatt gactgcctgg ggagtcgctc caacaagcag cggcagcaga tcctactttc      960

cttcaagacg gcttacggca aggatttgat caaagatctg aaatctgaac tgtcaggaaa     1020

ctttgagaag acaatcttgg ctctgatgaa gaccccagtc ctctttgaca tttatgagat     1080

aaaggaagcc atcaaggggg ttggcactga tgaagcctgc ctgattgaga tcctcgcttc     1140

ccgcagcaat gagcacatcc gagaattaaa cagagcctac aaagcagaat tcaaaaagac     1200

cctggaagag gccattcgaa gcgacacatc agggcacttc cagcggctcc tcatctctct     1260

ctctcaggga aaccgtgatg aaagcacaaa cgtggacatg tcactcgccc agagagatgc     1320

ccaggagctg tatgcggccg gggagaaccg cctgggaaca gacgagtcca agttcaatgc     1380

ggttctgtgc tcccggagcc gggcccacct ggtagcagtt ttcaatgagt accagagaat     1440

gacaggccgg gacattgaga agagcatctg ccgggagatg tccggggacc tggaggaggg     1500

catgctggcc gtggtgaaat gtctcaagaa taccccagcc ttctttgcgg agaggctcaa     1560

caaggccatg aggggggcag gaacaaagga ccggaccctg attcgcatca tggtgtctcg     1620

cagcgagacc gacctcctgg acatcagatc agagtataag cggatgtacg gcaagtcgct     1680

gtaccacgac atctcgggag atacttcagg ggattaccgg aagattctgc tgaagatctg     1740

tggtggcaat gactgaacag tgactggtgg ctcacttctg cccacctgcc ggcaacacca     1800

gtgccaggaa aaggccaaaa gaatgtctgt ttctaacaaa tccacaaata gccccgagat     1860

tcaccgtcct agagcttagg cctgtcttcc acccctcctg acccgtatag tgtgccacag     1920

gacctgggtc ggtctagaac tctctcagga tgccttttct accccatccc tcacagcctc     1980

ttgctgctaa aatagatgtt tcatttttct gactcatgca atcattcccc tttgcctgtg     2040

gctaagactt ggcttcattt cgtcatgtaa ttgtatattt ttatttggag gcatattttc     2100

ttttcttaca gtcattgcca gacagaggca tacaagtctg tttgctgcat acacatttct     2160

ggtgagggcg actgggtggg tgaagcaccg tgtcctcgct gaggagagaa agggaggcgt     2220

gcctgagaag gtagcctgtg catctggtga gtgtgtcacg agctttgtta ctgccaaact     2280

cactcctttt tagaaaaaac aaaaaaaaag ggccagaaag tcattccttc catcttcctt     2340

gcagaaacca cgagaacaaa gccagttccc tgtcagtgac agggcttctt gtaatttgtg     2400

gtatgtgcct taaacctgaa tgtctgtagc caaaacttgt ttccacatta agagtcagcc     2460

agctctggaa tggtctggaa atgtca                                          2486


<210>  216
<211>  2535
<212>  DNA
<213>  homo sapiens

<400>  216
gcactgcctc tggcacctgg ggcagccgcg cccgcggagt tttccgcccg gcgctgacgg       60

ctgctgcgcc cgcggctccc cagtgccccg agtgccccgc gggccccgcg agcgggagtg      120

ggacccagcc cctaggcaga acccaggcgc cgcgcccggg acgcccgcgg agagagccac      180

tcccgcccac gtcccatttc gcccctcgcg tccggagtcc ccgtggccag gtgtgtgtct      240

ggggaagaga cttacagaag tggagttgct gagtcaaaga tctaaccatg agctaccctg      300

gctatccccc gcccccaggt ggctacccac cagctgcacc aggtggtggt ccctggggag      360

gtgctgccta ccctcctccg cccagcatgc cccccatcgg gctggataac gtggccacct      420

atgcggggca gttcaaccag gactatctct cgggaatggc ggccaacatg tctgggacat      480

ttggaggagc caacatgccc aacctgtacc ctggggcccc tggggctggc tacccaccag      540

tgccccctgg cggctttggg cagcccccct ctgcccagca gcctgttcct ccctatggga      600

tgtatccacc cccaggagga aacccaccct ccaggatgcc ctcatatccg ccatacccag      660

gggcccctgt gccgggccag cccatgccac cccccggaca gcagccccca ggggcctacc      720

ctgggcagcc accagtgacc taccctggtc agcctccagt gccactccct gggcagcagc      780

agccagtgcc gagctaccca ggatacccgg ggtctgggac tgtcaccccc gctgtgcccc      840

caacccagtt tggaagccga ggcaccatca ctgatgctcc cggctttgac cccctgcgag      900

atgccgaggt cctgcggaag gccatgaaag gcttcgggac ggatgagcag gccatcattg      960

actgcctggg gagtcgctcc aacaagcagc ggcagcagat cctactttcc ttcaagacgg     1020

cttacggcaa ggatttgatc aaagatctga aatctgaact gtcaggaaac tttgagaaga     1080

caatcttggc tctgatgaag accccagtcc tctttgacat ttatgagata aaggaagcca     1140

tcaagggggt tggcactgat gaagcctgcc tgattgagat cctcgcttcc cgcagcaatg     1200

agcacatccg agaattaaac agagcctaca aagcagaatt caaaaagacc ctggaagagg     1260

ccattcgaag cgacacatca gggcacttcc agcggctcct catctctctc tctcagggaa     1320

accgtgatga aagcacaaac gtggacatgt cactcgccca gagagatgcc caggagctgt     1380

atgcggccgg ggagaaccgc ctgggaacag acgagtccaa gttcaatgcg gttctgtgct     1440

cccggagccg ggcccacctg gtagcagttt tcaatgagta ccagagaatg acaggccggg     1500

acattgagaa gagcatctgc cgggagatgt ccggggacct ggaggagggc atgctggccg     1560

tggtgaaatg tctcaagaat accccagcct tctttgcgga gaggctcaac aaggccatga     1620

ggggggcagg aacaaaggac cggaccctga ttcgcatcat ggtgtctcgc agcgagaccg     1680

acctcctgga catcagatca gagtataagc ggatgtacgg caagtcgctg taccacgaca     1740

tctcgggaga tacttcaggg gattaccgga agattctgct gaagatctgt ggtggcaatg     1800

actgaacagt gactggtggc tcacttctgc ccacctgccg gcaacaccag tgccaggaaa     1860

aggccaaaag aatgtctgtt tctaacaaat ccacaaatag ccccgagatt caccgtccta     1920

gagcttaggc ctgtcttcca cccctcctga cccgtatagt gtgccacagg acctgggtcg     1980

gtctagaact ctctcaggat gccttttcta ccccatccct cacagcctct tgctgctaaa     2040

atagatgttt catttttctg actcatgcaa tcattcccct ttgcctgtgg ctaagacttg     2100

gcttcatttc gtcatgtaat tgtatatttt tatttggagg catattttct tttcttacag     2160

tcattgccag acagaggcat acaagtctgt ttgctgcata cacatttctg gtgagggcga     2220

ctgggtgggt gaagcaccgt gtcctcgctg aggagagaaa gggaggcgtg cctgagaagg     2280

tagcctgtgc atctggtgag tgtgtcacga gctttgttac tgccaaactc actccttttt     2340

agaaaaaaca aaaaaaaagg gccagaaagt cattccttcc atcttccttg cagaaaccac     2400

gagaacaaag ccagttccct gtcagtgaca gggcttcttg taatttgtgg tatgtgcctt     2460

aaacctgaat gtctgtagcc aaaacttgtt tccacattaa gagtcagcca gctctggaat     2520

ggtctggaaa tgtca                                                      2535


<210>  217
<211>  5173
<212>  DNA
<213>  homo sapiens

<400>  217
aatcggtggc cgccagacac ccgcggcgaa ggcggctcgg gctcgggctc cggatgtgct       60

aggtgtgggc cggcccccac ccgaccctga caagtgacca tggatcctgg agccgggtca      120

gagacatctc tgactgtcaa tgagcaggtc atcgtgatgt caggtcatga gaccatccga      180

gtgctggaag tcggagtgga tgcccaactc cctgctgagg aagagagcaa aggactggag      240

ggtgtggccg ccgagggctc ccagagcgga gaccctgctg aagccagtca agctgctggt      300

gaagctgggc cagacaacct gggctcctct gcagaggcaa ctgtgaagtc acccccgggg      360

atccctccga gccctgcccc tgccattgcc accttcagcc aagccccaag ccagcctcag      420

gcatcgcaga ccctgacgcc actggctgta caagctgccc cccagtattg caggtcaagt      480

ggctggtcag caggggctgg ccgtgtggac aattcctaca gcaactgtgg ctgccctccc      540

aggactgacc gctgcttctc ctacgggggg agtgttcaag ccacctttag ccggtctcca      600

agcagctgct gtgctgaaca ccgctcttcc ggcaccggta caagctgccg caccagtaca      660

ggcctcctcg acggcccaac cccggccacc agcccagccc cagacgctgt tccagaccca      720

gccgctgctg cagaccacac ctgccatcct cccgcagccc actgctgcca ccgctgctgc      780

ccctaccccc aagccagtgg acaccccccc acagatcacc gtccagcctg caggcttcgc      840

atttagccca ggaatcatca gtgctgcttc cctcggggga cagacccaga tcctggggtc      900

cctcactaca gctccagtca ttaccagcgc cattcccagc atgccaggga tcagcagtca      960

gatcctcacc aatgctcagg gacaggttat tggaaccctt ccatgggtag tgaactcagc     1020

tagtgtggcg gccccagcac cagcccaaag cctgcaggtc caggccgtga ccccccagct     1080

gttgttgaac gcccagggcc aggtgattgc gaccctggct agcagccccc tgcctccacc     1140

tgtggctgtc cggaagccaa gcacacctga gtcccctgct aagagtgagg tgcagcccat     1200

ccagcccaca ccaaccgtgc cccagcctgc tgtggtcatt gccagcccag ctccagccgc     1260

caagccatct gcctctgctc ctatcccaat tacctgctca gagaccccca ccgtcagcca     1320

gttggtgtcc aagccacata ctccaagtct ggatgaggat gggatcaact tagaagagat     1380

ccgggagttt gccaagaact ttaagatccg gcggctctcg ctgggcctta cacagaccca     1440

ggtgggtcag gctctgactg caacggaagg tccagcctac agccagtcag ccatctgccg     1500

gttcgagaag ctagacatca cacccaagag tgcccagaag ctaaagccgg tgctggaaaa     1560

gtggctaaac gaagctgaac tgcggaacca ggaaggccag cagaacctga tggagtttgt     1620

gggaggcgag ccctccaaga aacgcaaacg ccgcacctcc ttcacccccc aggccataga     1680

ggctctcaat gcctattttg agaagaaccc actgcccaca ggccaggaga tcactgaaat     1740

tgctaaggag ctcaactacg accgtgaggt agtgcgggtc tggttctgca atcggcgcca     1800

gacgctcaag aacaccagca agctgaacgt ctttcagatc ccttagggct cagcccctgg     1860

ccctgtgttc tagcactttg tccatttccc gtggcatccg gctgcagcca ctgccatgac     1920

agcacctgtc attttgccac gtgcagctgt gctcacccca ggtcatcaga ctccaccgtg     1980

tgcatgtgca tcaatgtccc tcttttctcc cacacatctc acatcatggg gaggccagag     2040

ggggccacac gagagctcca ggctctgggc tggtcactcc gaagaagagg atttgtgacg     2100

tcacttagag aagcaccttg ctagcatggt ttctgaaggg tgaattctgg tggggaacca     2160

gaaactccct gtctttgggg cagggctaaa gcagctccta aggaccactg gccattagct     2220

cttgcttttg atggcattct ctttccacct tgtcttctcc tttgctcctc tgtgttagtg     2280

tggcaggtat gacaactcat ccagtggaaa cacagcctca cactgccctt ccgcccccca     2340

cactttgcct gcaggtgcac cgaaaggacc tgggagataa aattcaaaaa agtgtgatgt     2400

gctgctcaga aggtcagact ccatgtctgc cttgacctca aggtcagaag gttcccaaac     2460

ccctggggct ggaacatggg atctcctctt ccacctcttc ctggttcctt tgcggggaaa     2520

attgcactaa aacagaacct tttcttaatc catgttggaa ggaagcaaca gtgaactcta     2580

cctgttctgg agttctcctg ggtctgcaga aggttgggaa tttagaaaat aaggctgttc     2640

tttcatattt taatttaatc tctgtcaatg gccatccctc ccacaaaaaa acgtgggtta     2700

agagaacttg cagactggat atgcaagcaa acgggcaact ctggagaaaa ataaggaaag     2760

gaatgctgac tttctctttc tttctcttgt ccccacaccc attcccaacc caatactggg     2820

gccttctcaa aaggagcaaa ttaaacaata aaccagacag caaggccctg ggggaaagga     2880

caacatcctg aaataaatga tggagcccag gaaggtctct tgtggaagtt gacttaactc     2940

taattttctt tgtaacttta agccttggat acgggaggag aaatctcatt ttgtcgagtc     3000

tcagaccatg tctgtgtgta agcaatcccc acagtgtcct ctgagccaag gacaccccca     3060

gatcagattg agttttgctt ctagacgggg tagctatggt accttggggg ttagctctca     3120

tccaagctgt taagtgagtt tccagcctca ctgtggctgg aaagccccta aaattcagta     3180

tgtaactcca ggaagtcagg agagaactga gatttgccta gatgaccaca ggcttgcggt     3240

gtagattatc cctaaagggc cccaagtcac gggggtcaac cacccctgtc ttcagtactc     3300

ttatccttac agaggctggt ctctaacagc tgcctccagt ggacctccca tgatccaccc     3360

tgagggaagg accgtcagct ggggacacat caccacctct gtcagtcact ggtgcagagc     3420

cacctcctag cctagcttcc tctggtgtcc tgtttccttt cccacttact gttggtgcct     3480

cccaggccct gcagtgccag cgtggccacc ctcttggtag cctggccagt aagaggagga     3540

cagttgtgtg ctgaattagc acacgcacgt gcagcgcgca cagacgcgcg cacacacaca     3600

cacatacacg ctctgctgca tttggacaaa ccatgcctgc cagagtgtag cagaggtgag     3660

gaagcaggtg ggcagcttgc ctgacccagc ttttcaggag agcgtgtctc caacagagag     3720

tctccacact ctagttcagg gttatcgacc tgcctcaatg agatgacaga ctcatttggg     3780

aggggtgttg caaacaagtt ttcagtgaga atagttaagt tccagagctt gtaaaggatt     3840

cagtgactga cacttcagta aattaggcca ggcacattgg cttatgcctg taattccaac     3900

actttggaag gccgaggtgg gcggatcatt tgaggtctgg agttcgagac cagcctgacc     3960

aacatggtga aaccccgtct ctactaaaaa tacaaaaatt agccaggtgt ggtagtgcac     4020

atctgtaatc ccagctactt gggaggtgga ggcaggagaa ttgcttgaac cctggaggtt     4080

gcaatgagct gagatcacac tacttcactc cagcctgggt gacagagcaa gactcggtct     4140

caaacaaaca aaaacttatg gcgatgcagg ttttcatgct cagacgcttg cattcaggta     4200

tgctttcttt tttgagagag acaaatgggt cacagctggc accctgggaa tagcacataa     4260

tccagggtgt gtctgtggtg gtggacgtgc aggggaacac catctgtcct gtgtcatgat     4320

gggaaaacaa tcatgaacca ctggtctaaa ttaggcctgg ccatgctttc tcagcccctc     4380

cctcatttaa atttgtcttc ccaaagctga gctaaaacta aaccatttct cctctgctgg     4440

aatgatggat tggtcattca gaggaacaat accaggggtg ggaggtttgc aggctgagtt     4500

ccccaggcat gggggtgcag ggtgtccctg aggtttaccc aaagcacagc tcgctggcct     4560

gtgacctctg cccttcctcc cacagtgtaa gaccccccag gaagcagctg gggcctgaac     4620

ctctcaccta ggaggtaggt ttattttatt ttttgttagc atcaggctct gaaggagttg     4680

gtatacattt tgttttgaaa acatcttctg gacttacacc agagcttagt gtcgtcttta     4740

ctatggaaag agaggagaat ggacagaaat ggtttaactg tgtggagttt tgtttgtttt     4800

gttttaaatg gaagaaagac caaaactttc ctggtggatc agctagggcc tttgaccctg     4860

cattaccacg gcattttatc caggtgaagt ccagggaaag aactcagcca aatggactaa     4920

ggaacacacg agtttggaat gcgagactct gacatttttg tgttcttgga aatccaatta     4980

ccttcccatg cccagatttc cttcctgcct cttggaccag gctctggcac tgaggttctc     5040

actgttccca acacagacaa agcttcctga gggctggagg ggcagcaagg ggagaggaga     5100

atggggaaga agcgcttgat gtagttgtgt ggaataaaca gtattttttc ttttgtaaaa     5160

aaaaaaaaaa aaa                                                        5173


<210>  218
<211>  2324
<212>  DNA
<213>  homo sapiens

<400>  218
atctctcagc gcagcaggac acggggacca tgcaagctgt aattggtcag gcatgaactc       60

tcttgggttg tgttaccctg tttgctgttt actgtcaaga tgctgaaaga atgttcttat      120

aatgatccaa gaggaagtgg caaatgagtg ctcttcttca ggatccaatg atagctggac      180

aagtcagtaa gcccttgctg tcagtgcgga gtgaaatgaa tgcggagttg agaggtgagg      240

acaaggctgc tacttcagac agcgagctga atgagcccct gcttgcgcct gtggaatcaa      300

atgacagcga ggacactccc agcaagctct tcggggctag aggaaaccca gcattatcag      360

acccaggcac tcctgaccaa caccaggcca gtcagaccca ccccccattt ccagttgggc      420

cacagccact tctgacggca cagcagttag cttctgctgt ggccggcgtg atgccgggag      480

gccccccagc cctcaaccag ccaatcctca ttcccttcaa catggcggga cagctaggag      540

gccagcaagg actggttctc acactgccaa cagcgaatct caccaacatc caagggctgg      600

tggcagcagc tgcagccgga ggcattatga ctctgccact gcaaaatcta caagctacct      660

catccctgaa ctcccagctc cagcagctcc agctccagct ccagcagcag cagcagcagc      720

agcagcagca gcctcccccg tcaaccaacc agcacccgca accagcccca caggcgccct      780

cgcagtccca gcagcagccg ctgcagccca ccccacccca gcagccacca cccgcctctc      840

agcagccgcc agctcctaca tctcagctgc aacaggcgcc tcagccccag cagcaccaac      900

cccactccca ctcccagaac cagaaccaac catctccaac ccagcagagc tccagccccc      960

cgcagaaacc tagtcagtct ccaggacatg gcctgccttc accgctcacg ccacccaatc     1020

ctctacagct ggttaataat ccactagcaa gtcaggctgc agcggctgca gcagccatga     1080

gctccatagc aagctcacag gcctttggca atgccctctc cagtcttcag ggggtcacag     1140

gtcaactagt tactaatgca caaggacaga ttatcgggac cattccactg atgcctaatc     1200

cagggccatc gagccaagca gcaagcggca ctcagggctt gcaagtgcag ccaatcaccc     1260

cccagctcct cacaaacgcc cagggccaga tcatcgccac agtcattggg aaccagatcc     1320

tgcccgtgat caacacccag ggcatcacgc tgtcacccat caagcccggc cagcagctcc     1380

accaaccctc ccagacgtca gtgggtcaag cagcctccca aggcaacctt ctgcacctgg     1440

ctcacagcca agcatccatg tctcaaagtc ccgtccggca ggcttcctct tcttcctcct     1500

catcctcctc ttcttcagct ttgagcgtgg gccagttagt cagcaatcct caaacggcag     1560

cgggtgaggt ggatggggtt aatctggagg agatccgaga atttgccaaa gcttttaaaa     1620

tccggcgcct gtcccttggc ctgacccaga ctcaggtggg acaggctctc agtgctacag     1680

agggccccgc gtacagccag tcggccatct gcagacacac catcctgaga agccactttt     1740

tcctaccaca ggaagcccaa gagaacacta tagctagcag tctgacagcc aaactgaacc     1800

ctggcctttt gtatcctgcc aggtttgaaa agctggacat cacccctaaa agtgcccaga     1860

agatcaagcc ggtgcttgag cggtggatgg ctgaggctga ggcccgccat cgagcaggta     1920

tgcagaacct gaccgagttt atcgggagtg aaccatccaa aaagcgcaag cggcgcacct     1980

ccttcacacc ccaggccctt gagatcctca atgcccactt tgagaagaac acacaccctt     2040

ctgggcagga aatgaccgaa attgctgaga agctgaacta tgaccgagaa gtagttagag     2100

tttggttctg caataagagg caagccctga agaacacaat taaacgctta aaacagcacg     2160

agccggccac ggcagtccct ttggagccct taacagactc tctggaagaa aactcctaaa     2220

gagatgccca cccataatca gaagcaaaat tcacagaaac taaactccac ccttgggact     2280

ccacaacaac aacaacaaca aaatttaatt taatttaaaa atag                      2324


<210>  219
<211>  1077
<212>  DNA
<213>  homo sapiens

<400>  219
ggcggtccgg gcgggtgact ggcggcgggc gccgcggtcg ggctggctgc cgggcagcat       60

ggaggagctg agcagcgtgg gcgagcaggt cttcgccgcc gagtgcatcc tgagcaagcg      120

gctccgcaag ggcaagctgg agtacctggt caagtggcgc ggctggtcct ccaaacataa      180

cagctgggag ccggaggaga acatcctgga cccgaggctg ctcctggcct tccagaagaa      240

ggaacatgag aaggaggtgc agaaccggaa gagaggcaag aggccgagag gccggccaag      300

gaagctcact gccatgtcct cctgcagccg gcgctccaag ctcaaggtgg gtggctgcgc      360

tgggtatgct gaccccacct cccagcaccc ccttggcgta gggggcaggc agagggaggg      420

tttggggccc tcaggaaggg ggtggcactt ctgccaacag tctgtccctc tactcggaaa      480

acaggagccc cctttcttcc tgtctctcag cttctgctgc caggggcccc agccggctga      540

gagttcctcc ccgcccctcc caggggcttc ctgcttcagc ctgtcctgca cgcctctctg      600

ctgggtggca gggtcaaact gctgcagaca agcactcttc cctcccaggg ggtccttggg      660

ggacggaaag gaacaggaag catgcgtaca gtaggtgctc ataggattgc cggctggatg      720

tgactcaaaa gcctaagatt tgggggctac tccgggccca cctgcgggtg caccttaaat      780

cgaggtggcc acgaaaggca gggctgactg aatagccagg gggtgccagg aggggccttg      840

gaggagggca gaggcagtgt gggctgatga tgtgctttgg ccttctcggg actgtcctgt      900

cacccctcct cgctacagtg atgggctcac cccgccacag gtatgcatgc gcccctgggg      960

tccgtggtag ggcccctccc tcccctgagg acaggtgagg caggacagga tgggggagga     1020

gggcctggcc tcagtcccgg gtgtggcttt gattccctcc tccgggcact gtccctg        1077


<210>  220
<211>  5878
<212>  DNA
<213>  homo sapiens

<400>  220
attgggtaca tgcgcagtgc cgctcgcgcg ggccgcgcca atcctgcagc gccttcaaca       60

ggtttcgggc ggcgaattcc agttctccgg gttttggggc tccctgcggg aggcagtgct      120

ggatctggga atctctagga aaggaaagag caaaggaggg gaaagatggg gggctgcagt      180

ctccacgtac gtccctcaaa gcgcgtccta aaacccggat aaccggagcg ctccccatgg      240

accacacgga gggctcgccc gcggaggagc cgcctgcgca tgctccatcg cctgggaaat      300

ttggtgagcg gcctccacct aaacgactta ctagggaagc tatgcgaaat tatttaaaag      360

agcgagggga tcaaacagta cttattcttc atgcaaaagt tgcacagaag tcatatggaa      420

atgaaaaaag gtttttttgc ccacctcctt gtgtatatct tatgggcagt ggatggaaga      480

aaaaaaaaga acaaatggaa cgcgatggtt gttctgaaca agagtctcaa ccgtgtgcat      540

ttattgggat aggaaatagt gaccaagaaa tgcagcagct aaacttggaa ggaaagaact      600

attgcacagc caaaacattg tatatatctg actcagacaa gcgaaagcac ttcatgttgt      660

ctgtaaagat gttctatggc aacagtgatg acattggtgt gttcctcagc aagcggataa      720

aagtcatctc caaaccttcc aaaaagaagc agtcattgaa aaatgctgac ttatgcattg      780

cctcaggaac aaaggtggct ctgtttaatc gactacgatc ccagacagtt agtaccagat      840

acttgcatgt agaaggaggt aattttcatg ccagttcaca gcagtgggga gcctttttta      900

ttcatctctt ggatgatgat gaatcagaag gagaagaatt cacagtccga gatggctaca      960

tccattatgg acaaacagtc aaacttgtgt gctcagttac tggcatggca ctcccaagat     1020

tgataattag gaaagttgat aagcagaccg cattattgga tgcagatgat cctgtgtcac     1080

aactccataa atgtgcattt taccttaagg atacagaaag aatgtatttg tgcctttctc     1140

aagaaagaat aattcaattt caggccactc catgtccaaa agaaccaaat aaagagatga     1200

taaatgatgg cgcttcctgg acaatcatta gcacagataa ggcagagtat acattttatg     1260

agggaatggg ccctgtcctt gccccagtca ctcctgtgcc tgtggtagag agccttcagt     1320

tgaatggcgg tggggacgta gcaatgcttg aacttacagg acagaatttc actccaaatt     1380

tacgagtgtg gtttggggat gtagaagctg aaactatgta caggtgtgga gagagtatgc     1440

tctgtgtcgt cccagacatt tctgcattcc gagaaggttg gagatgggtc cggcaaccag     1500

tccaggttcc agtaactttg gtccgaaatg atggaatcat ttattccacc agccttacct     1560

ttacctacac accagaacca gggccgcggc cacattgcag tgcagcagga gcaatccttc     1620

gagccaattc aagccaggtg ccccctaacg aatcaaacac aaacagcgag ggaagttaca     1680

caaacgccag cacaaattca accagtgtca catcatctac agccacagtg gtatcctaac     1740

taccgtcttt ttgctaggac ttaaactgac ttgagtgtgg caaaaagtta acaaaaaagg     1800

agaaaaaatg aacaatcgtt tgtggtttct tgggaaaact tttcatacca ggtgatacta     1860

ttcaaaaacc ccgttgtctc cctgcaagtg ctgatttgaa atgcagaagc cacagtaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaagaaaaaa aaatcaaaat gtataaatat tggaaatcaa     1980

gtttttcagc tgttttgttg gttggttggt tggtttttgt ttggttttgt ttaaatgggc     2040

aagaagtaaa taatgtggct ggaatacaag ttgaacaaac tagaagacac aaatctaaca     2100

tagtttttat ggaccaagga acttgtatat tgtataagct ttagtaaaag gtacattttc     2160

accatacctt tttttatatc acggtattat agtacacctt gttaccaaat aggttgttct     2220

cttccccacc cacctttgag cttttgctct aaaatacatt caggttccaa gcctgaccat     2280

ccttgtttaa tctatcatac tcttccaggt tttttttttt tggtctaagg ctggaacttt     2340

tttctttttt ttcagctgaa gtcttatgac ttttcatgag tcaaaattgt ttggatttca     2400

gcaagtcaaa tcttgcaaag gcctgcatat tttttttaag attatatgaa gtctgtgcaa     2460

aagctttaaa aaaatgcctc tgccttgcct gcaatacatg caatgtatgt taacttagtc     2520

tctcttctca gacactgttg gtagttattt ctgtgttttc ctttttttaa aaaaaaatat     2580

ggacttattg tggttatctg agaggttcta acattcacat gcaatttggt gtggccattt     2640

agctattaat gagttaatgg cgcagaactt gttgatattt gaagtgttct ctcccctttt     2700

cccatgacgt aaatacatag gtgtgttcca ggatttgttc aggtttttcc cccctcctaa     2760

tcttgtacat aacttgtatt atgtgtaagt taaacatttt attttgaact tggaatgttc     2820

ccagtgattt cattcagcag ggtattttct gccttgttgg caagtgacaa aaaatatggg     2880

aagtatttgc taccagttgg tagatggtgc ccttaatggt agaatgagga aaatgtccgc     2940

aaaagcatgt tttattatct ttactttttt ggggggttgg agggggtagc ctagccagaa     3000

catcattgta atcttaaaac ataagatgct tttattagat gatcaactaa aatagctgga     3060

agacagtact ttagaaacag atagttgtaa gattataaaa tgcaaatgta acttatgttt     3120

tcattttttt ctctgccttt tttgtttgtt tgttttctct tttccagtac tgagcatctc     3180

cacaaatgtc tcctaactca gaaaatgttt cttttctttt cagttgagat ttggttgcat     3240

tcagggttgt aggttggcct tgcttgctaa ccccgccggt tttaccgtgc tttcattcct     3300

gaactttgtt tatgcctttg tttggtttct tcgaaattgc agcagactca ttgggctaca     3360

tttagtacag gaaccacgtg tgtaatgtta tacaacacag tctagtaata caatcatccc     3420

tcttagagta aaaactacct ctagattgtg gtaagctttt actgtcccat aaaacaggag     3480

ccacagtacc ttatgaatgc aaaactgtaa cttcctacag tgtttcccta cagaacattg     3540

tctttctggt gtcctgggct gttttgaaaa agtttccatt aatagacttt ttagaaatta     3600

ttattagtag catttttttt ccagctttgc tgtcttcatc actcactcta tgctcagact     3660

atgccactgt aaatattctt cctaacatct ttaaatcgcc ttttcctcag ttttcaaggg     3720

gaaggtcatt tgtaaagcac gttaggtggt taaatcagtt attgcggttt tctcttactg     3780

caagcctttt taatcacccc caggctgcat tttattctat atcgcctttt ttcttcaaat     3840

ctgctccaat cactcacttc tctcttataa gctaatcctg cctcacacct taaatctgtt     3900

tcagtgatca agggcagaac tcattgtggc cttatctttc tttgttgtaa ttgttcactg     3960

tctctttctt acagaccact tatttctgag tagtagttat tcctctctat ggagtcatgg     4020

caggaatcat tacacagtgc ttttgttcag agcatggaca tgttcctagt gctgctttgc     4080

tttaacggcc acaagtttcc tccacttcct aggtttggta tttagttaag gaatcatatt     4140

aaattaacca ataacaaaag agatactttt gaagaacaaa ctattcctta cccatttttg     4200

tagctcaaaa ataatttttc aagttcatga ccttattaaa atgaacttgt gtttttttaa     4260

caaacatgta tgttttattt tgatagtttc tttccgtaag ataattgaaa tattatactg     4320

taaacccttt tcttttcttt ttttgaaaag tccaagaatg tacttataca ggcatttttc     4380

cccacctatt tttggccatt ctcataccac agactaaaga gtgaaatgat ttgtccattg     4440

tagcttattg tttatcagta gttcttttgt cagctgctta cattttttct ttcatggttt     4500

tgtgaatcat tttcagtatg taatttatag gaaccttgtc ctctggttat agtagactgt     4560

gtgccctcct ccagtgatgg cattattaga catgctggtc atttaccctc agaaagactc     4620

tcttattaga atggtgagtg cttcagttat agtatgtttg aatttttaaa aaattctgtt     4680

ttagaaatgt atcttatgct ctcatgacta tgcagtttct aaacatacac atagaagctg     4740

agtctctgat ccaatatgtt tttatttgtt ccatttaatt tatcacatag attgggaagg     4800

caagctaaaa gccttaaaaa tgccctttat attttgagtg atttcagcgt tgaacactag     4860

tatactatct aaatttgctg ctcactttct ttaaactgtg gcaattaaag gcatgtttat     4920

acatgactta atcgtgaaat gtttgtcact cttactgcac agacttatct gcaatcataa     4980

ctggttagtt tttttgtttt gttttgtttt attgttttta atgaaactgg taccatctgt     5040

gctttcacaa aaaacttcca atgccatttt tgagaactaa cctaactagt catgctaacc     5100

agaaaatcca ctggggagga ggttcctttt gaaacaaaat gctgttcagt tagtaaccaa     5160

gttactttga ttgcaaaagc agctgtgttt ctgataagta ctgaacaaat gtgtgtaatt     5220

ttctgtgcca gacttatgac tttgttttca agcactgtaa tgtgggatgg atggttagaa     5280

acaataatat attagggttt ctgtttaacc ctttcaggac tgaactgtat ctccttttgt     5340

taattttccc ctgtgttgtg ataaatgttt gccagcattc agtactgtgt tggtccagat     5400

gtaggtttat atgctcattt ttagcttatt tcttgtacct tgcagcatgc tctacgcatt     5460

cagtccttaa ggggtttatt ttacaaactg tgcgcctgta aggtttatta gcaataagat     5520

agaaaattga gcaagtttat accataattt tgtagaaaaa aagaatctgc tcagttccat     5580

atttcatccg tgaaaaactt gcaatacgag cagtttcaag gaataaataa aaaggaaatg     5640

taaaccattg taaaagtctt ctgtcgaatg tgcctgatgc atgtattatc gtcttttatt     5700

tcagaatact tcataaagat aaaattaaat tctatattat agttggtgta tttacaatct     5760

taccatgtac atcacatcaa agtgatagct ctactaattt aatttccttg tcaatgtttt     5820

taactatata gtgctttaaa gagatttttt ttccctgtgt aaaaaaaaaa aaaaaaaa       5878


<210>  221
<211>  9235
<212>  DNA
<213>  homo sapiens

<400>  221
cgcagataaa gtgagcccgg aaagggaagg agggggcggg gacaccattg ccctgaaaga       60

ataaataagt aaataaacaa actggctcct cgccgcagct ggacgcggtc ggttgagtcc      120

aggttgggtc ggacctgaac ccctaaaagc ggaaccgcct cccgccctcg ccatcccgga      180

gctgagtcgc cggcggcggt ggctgctgcc agacccggag tttcctcttt cactggatgg      240

agctgaactt tgggcggcca gagcagcaca gctgtccggg gatcgctgca cgctgagctc      300

cctcggcaag acccagcggc ggctcgggat ttttttgggg gggcggggac cagccccgcg      360

ccggcaccat gttcctggcg accctgtact tcgcgctgcc gctcttggac ttgctcctgt      420

cggccgaagt gagcggcgga gaccgcctgg attgcgtgaa agccagtgat cagtgcctga      480

aggagcagag ctgcagcacc aagtaccgca cgctaaggca gtgcgtggcg ggcaaggaga      540

ccaacttcag cctggcatcc ggcctggagg ccaaggatga gtgccgcagc gccatggagg      600

ccctgaagca gaagtcgctc tacaactgcc gctgcaagcg gggtatgaag aaggagaaga      660

actgcctgcg catttactgg agcatgtacc agagcctgca gggaaatgat ctgctggagg      720

attccccata tgaaccagtt aacagcagat tgtcagatat attccgggtg gtcccattca      780

tatcagtgga gcacattccc aaagggaaca actgcctgga tgcagcgaag gcctgcaacc      840

tcgacgacat ttgcaagaag tacaggtcgg cgtacatcac cccgtgcacc accagcgtgt      900

ccaacgatgt ctgcaaccgc cgcaagtgcc acaaggccct ccggcagttc tttgacaagg      960

tcccggccaa gcacagctac ggaatgctct tctgctcctg ccgggacatc gcctgcacag     1020

agcggaggcg acagaccatc gtgcctgtgt gctcctatga agagagggag aagcccaact     1080

gtttgaattt gcaggactcc tgcaagacga attacatctg cagatctcgc cttgcggatt     1140

tttttaccaa ctgccagcca gagtcaaggt ctgtcagcag ctgtctaaag gaaaactacg     1200

ctgactgcct cctcgcctac tcggggctta ttggcacagt catgaccccc aactacatag     1260

actccagtag cctcagtgtg gccccatggt gtgactgcag caacagtggg aacgacctag     1320

aagagtgctt gaaatttttg aatttcttca aggacaatac atgtcttaaa aatgcaattc     1380

aagcctttgg caatggctcc gatgtgaccg tgtggcagcc agccttccca gtacagacca     1440

ccactgccac taccaccact gccctccggg ttaagaacaa gcccctgggg ccagcagggt     1500

ctgagaatga aattcccact catgttttgc caccgtgtgc aaatttacag gcacagaagc     1560

tgaaatccaa tgtgtcgggc aatacacacc tctgtatttc caatggtaat tatgaaaaag     1620

aaggtctcgg tgcttccagc cacataacca caaaatcaat ggctgctcct ccaagctgtg     1680

gtctgagccc actgctggtc ctggtggtaa ccgctctgtc caccctatta tctttaacag     1740

aaacatcata gctgcattaa aaaaatacaa tatggacatg taaaaagaca aaaaccaagt     1800

tatctgtttc ctgttctctt gtatagctga aattccagtt taggagctca gttgagaaac     1860

agttccattc aactggaaca tttttttttt ttccttttaa gaaagcttct tgtgatcctt     1920

tggggcttct gtgaaaaacc tgatgcagtg ctccatccaa actcagaagg ctttgggata     1980

tgctgtattt taaagggaca gtttgtaact tgggctgtaa agcaaactgg ggctgtgttt     2040

tcgatgatga tgatgatcat gatgatgatc atcatgatca tgatgatgat catcatgatc     2100

atgatgatga ttttaacagt tttacttctg gcctttccta gctagagaag gagttaatat     2160

ttctaaggta actcccatat ctcctttaat gacattgatt tctaatgata taaatttcag     2220

cctacattga tgccaagctt ttttgccaca aagaagattc ttaccaagag tgggctttgt     2280

ggaaacagct ggtactgatg ttcaccttta tatatgtact agcattttcc acgctgatgt     2340

ttatgtactg taaacagttc tgcactcttg tacaaaagaa aaaacacctg tcacatccaa     2400

atatagtatc tgtcttttcg tcaaaataga gagtggggaa tgagtgtgcc gattcaatac     2460

ctcaatccct gaacgacact ctcctaatcc taagccttac ctgagtgaga agccctttac     2520

ctaacaaaag tccaatatag ctgaaatgtc gctctaatac tctttacaca tatgaggtta     2580

tatgtagaaa aaaattttac tactaaatga tttcaactat tggctttcta tattttgaaa     2640

gtaatgatat tgtctcattt ttttactgat ggtttaatac aaaatacaca gagcttcttt     2700

cccctcataa gtagtgttcg ctctgatatg aacttcacaa atacagctca tcaaaagcag     2760

actctgagaa gcctcgtgct gtagcagaaa gttctgcatc atgtgactgt ggacaggcag     2820

gaggaaacag aacagacaag cattgtcttt tgtcattgct cgaagtgcaa gcgtgcatac     2880

ctgtggaggg aactggtggc tgcttgtaaa tgttctgcag catctcttga cacacttgtc     2940

atgacacaat ccagtacctt ggttttcagg ttatctgaca aaggcagctt tgattgggac     3000

atggaggcat gggcaggttc tcctttcttt ggaaacacat ccatgctggg atgcacagtt     3060

cttttcctaa ggattgtgtt tactcctgac tgcaacgtct tggccactgt ttggagcagt     3120

ttggtctgaa ggtcattaag gatctgcttg catcttgttt catgtcctcc gtgacagact     3180

gcagaccatg ttagaagaga aggaaggttt gtggatcaag agggttgaca ttaggtttgg     3240

tgagatgagt tgcttggcac agatcagcag aacaggaccc tggtgataag gcatctggct     3300

ttgctaacca cttatcatct tccattattc tctttcttaa ctaagtagac ccgaaagtgc     3360

acttttgaag tctggtttag atggcgagat tccgaatcta caatgatcga gtactggtgg     3420

ccacttttct ccaacattaa gtaaagagga ggagattcca ccttcagaaa gtgctgggaa     3480

gcattggctt tcttcccaca ttggtagaag agatggagga ggaaaccagg gtgcacattt     3540

ctacagatcc cctttgcctg ctggtgtttg ccttgtaaga taagtcactg gggggaaggg     3600

gaaatctatg aaatccaaga taaaggcata gtctttcagc tctattggtg ttaaaagtat     3660

atttgtgtcc aaatgttaat caacacaaat gtacagtact cagtactgac ttttttcact     3720

tcaaaatgtt ttcaagggaa attcagcaga cacccaactg tatttaatta gtgaaaagat     3780

ctataaagac tcttactttg aataaacaca ttaagtaagt gtgtcaaaat atttggaatg     3840

ccagttatct atgagcgcat atctcttaca gagtgtattt tgttttcatt aaggtatctc     3900

tgtgtatcta cactggacta atttcatagg gatctgattc tatgtgatcc actgtagaaa     3960

gctactgatt acttctgcag taacagcagc tctaattagc atcagatgac caaagcggaa     4020

atgggagttt cagcgctaac aagggcagcc ttcattgaag aatgcatggg taggcaatat     4080

ataaattaca ttttgaaaag cctcatctgt caccaacaaa tatctcattt ttcttcagtg     4140

ataaaagcat attcaagtta ccagctcctc aatttgaaaa tcagttgctg attaaataaa     4200

tagggggaag catcttgttc agggacaaca cgttagagag attcttatca aagcaagcca     4260

agcaaggttt ccgccattca gtgtgatctt agtttgacac ggtgacccta aaacaccatc     4320

atttgcccca gaactggagc acaataagtt aaatcattta cctgtctcac ttcttcttgg     4380

cgtgcttaaa agcaaaaatg attcgctact tcctgtcctt cagtccgggc atttggggtg     4440

ccactgaaga caggggttat ctgctgaggt ttgggtgtct tgcaggaagt atctcattgc     4500

agttgatttt gatgaaacca aacagtaact agggtccatg cagaccgtga ctccctgatt     4560

acatctagcc atgccctact tatttcagag agaaagagag ggggaataaa ggcagtattg     4620

ccacactgat tagaagcaca ttcattccac tttgatgttg aatatttttg accgatacat     4680

gcttgagtat ctttttaata gagcacatga aggaagaagc acacaatata gagaaggaat     4740

tgagaatgcc aattacatat ttatttttcc atacctgatt tttttcaagt ctgtaataaa     4800

aaaagtataa gttgagatta acataggtta tttttcatga agtatagcaa acgatctaga     4860

atgtgatagg agtgtggttt ccatttcttt tttttttttt ttaacagact tttgtgctgt     4920

agtaagaatg tcttagaagt tgtgtcttcg agttcctcaa acaccggaca gggctccccc     4980

agagctgcct cagcctttga tttggtccat attcagacac ttcctgtctt gcatacactc     5040

tgaggatggg ccgcttctag ctgccgcccg tctccctctt gccttcttgt ctctaaatca     5100

gacactccca agcactccat ctgctatact aggagagtgg gagagccaaa gcattttgga     5160

gtccatgtaa agtgcctggg aaaagagatg taagagcagt gggagtttat ataattagcg     5220

aattcttttc tcagaattca gcggaaatgt atttctgttg ttattattta caaaattgtg     5280

gcctcagagg agctgtcttt tggaaaataa gttttcattc atgcagttag ttagacatgc     5340

acgatgtact tgaatcaata aactgtggac cagaaaaggg ctgcttaaat gaattcacgt     5400

gttctaattc tctttcgagg ctgttgatga cctcctggat tcataccccc atgatctgtc     5460

ttgctcttgc ctctgttctt tgataaagca catcagacta tgtgacaccc atcttttcaa     5520

gaacgaccta aaagcaatga caacaggcag gagagaatta ccactggcct gggcacagtg     5580

acagcagaag gcccacctga gcttggagag ttggcgagat aaggcaaaat caaggtgcaa     5640

cagtgggcca tgttccaagg gtgaatggat ctgagagtcc gctgatgttc cttactgatc     5700

agaacaggga ccttctaacg aaacagccag agttccttga atcaggcaga agttctttag     5760

agacaggaag ccagagctat tgataatatc cgaacgacag aggaaggaat ttcttattag     5820

aaattctaaa ataaaacaag tggggatttg gttggatacc cttagaagct acatttttct     5880

ctcatcccta agatagatat ctcaagtgta tatctgacac ctcttggctt tgacacggct     5940

ctgcttctca agtgaccatt tgttttaagt ctgttgtcta gaattctttg tgggggctgg     6000

acctctgaaa aagattctca ctgcagaggc tttaaatctg tgtttttttc cactccctcc     6060

gtcctgggat gtattcggta ggacatttca tttatatcag gatattggct gattcagctc     6120

tctttcatcg ttattattca ggcctccctc caccaccttg ttctttattg cctaagtatt     6180

gccctcccca attcttcatc gtaatagctc taaatttagt ttgacccaaa ttaatttttg     6240

ttccaacaga tatattttaa gacagagaag cctctctcag gagccagatg atctgaagat     6300

gatgctaatc cccaaatacg aagttcctcc agctaactct cctctgagct ccctcttctt     6360

agctttggga ttggggatgg tctcatcctt gccaggaatc cctttgttgc tcccagtgtc     6420

tctgatgagc ttctcctccc tcccagagac aatgcagggg tggttttcag cagaatgtgc     6480

cacctgcact tctgattgtt ctgagaccca gcccagaggg gtggagaagg cgcacaaacc     6540

ctattccaat aaactgcctg cagagaacca cagcctgcta atagtcgttg aggtctcagc     6600

cccctaaggt ctccaagctc atttgaccag cgcagctgcg acttcggctg tctgcctctg     6660

gcaggtgcca atatcagcat cttgtcccac tgccatgggg agttaatttt tgctccaggg     6720

cagctgccaa gcccagcacc ggcatcaata gaaggttttc tctgattttc ttctcttcct     6780

ctcaggctag gctttcttac caatccccaa ttttcttctg tagggcgcca ggagactggc     6840

cagagatctt tagactctta cttagtttga acatctcttg ctgctcacac ccaggcttct     6900

tcagcagaaa gcatgaccca tagtaggtac tcagaaactg gttgaatgaa aagccttgac     6960

atttaagggc tttattctgt catacggtag caagaactgg cctattggca tcgtattcct     7020

ggcattgagc tgtattgacc ctgaatgtgt cctcctgagg tttttgaggg tgacctagga     7080

gaaagggtct gaaaaagcac tgggatccaa gtgactttaa atctgcccgt ggcatttcct     7140

gctgagaggc gagaaactag catctctccc aacaggctca catccgccag gaaggacaga     7200

gcccaaaacg ggggtagact ttgtgggaaa ttcgccagtt agtccgctga gattttaatc     7260

tgcctcaagc acaggatgct gacaagaaag gtagaccact cccccgatcc cagacaaacc     7320

ccaggggtga caacttctcc atcagtatcc tgagaagcaa catcaaatgc ttaccaagtc     7380

agcacgttta ctgagtgagt actctgacgg aataaaccag catttggagc tgaacttgag     7440

aacacagggc cctctgacag cagcttaggg aaacacccat cccttccaga ttggcagaat     7500

ccttccattt catgtccttc ggagacgctg tattctcttt acaaatcatt catgaaactg     7560

agactcagtc tcccaggggt aagtcctggg ccacgtgcaa acaatggcaa atccagctct     7620

tccatgatag agaaggcaaa cacacccacc ttcatcctga gcctaaaagg ccacctctga     7680

gcacttgggc agccactcct ctgggcctca gagggccatg agcttggcca ggtaggcaca     7740

gcggcgggga agtcacagct gtcaggtacc ggccatggtg caggtgggaa taggagatgc     7800

cagagctgct ttagctgagg aaagcaaaca gtcagcagtg ctcaaaggag caaaacttcg     7860

aatgtgcaca ttgacccctg acacctgcaa gcataacaca gatcctaaga ctagagtgaa     7920

gtaggaagaa gaattagaaa atccagtgga tgtcctgagt atagggaacc agggccgttg     7980

aaaatcagta aaggttgatt acctggggcg agaccgggtg actgtggcag tgcaggtgaa     8040

ggtaccctgg accttctcag ttcgctggca cataaggctc cgccaataaa gcgtggttct     8100

ctctgtcaca cacacacaca cacacacaca cacacacaca cacacacaca cacacacaat     8160

gattggaggg ctatatgatc cagcattagc ttcctggtgt gccaagcatg cttgatcggg     8220

aatttttttt tattattatt attttttagc tgtagctgaa ggcatttctc ggatgtggag     8280

aggagaatgg aaatcgcaga accaaatcag tttgccctgc catatttggc tgtggtctgt     8340

cattgggcat ttctgatgtg cttttctgga ttcaggaaga gctgattgtc ctccgagggt     8400

tgaaaaaaaa aaaacagttt cagaaacctg aatccagggc cttatagttc tcctcattat     8460

ctatcttctt ctcccttccc tcgcccaagg gagtggggga aacacttttc actgcagagt     8520

ttgctttaaa gttttcccat cttgcgtgca ttatcccttg atattaaaat tattttctca     8580

gtttaatcca actcctgctg agaagctgtg tgagatttag gctgtggggt ttttttcttg     8640

tactcttttg gatggtgttg catttttcac tcttaacccg agggtgtgtt tcagcttatg     8700

ttcgttctgt ttcatgcagg tttatagcac ggtagagtag aaggcggctt ctgattttta     8760

gggtattttt agaattcatt cctgagtgag gggttcagac acccagtctc ctcggaacag     8820

gggtgagggg tcgactgagc tttgttgaga agcctccagt taggcttcgg gcgggtctcc     8880

atgttatatt gtgtgtttac tgagcttccc actggtagaa gatgacacat ttgtccatcg     8940

tcctgtgtat ctgctttcca gaggacaccg gagcattctc ctggggtcac tcccacatgg     9000

ctgcctcaca tagctgtttt gcaacagcct ttattgccaa cacccttgga agaacatctc     9060

ctgtagaagt acaagttttg caatatggac tttggaagtg gttttgtgat gttcgaattt     9120

tctgttagcc tattgctcaa gcactacaga atgtacatag tccctttggc catcctctca     9180

ccccagaata tcctaataaa cattgttttc ttttttaaaa aaaaaaaaaa aaaaa          9235


<210>  222
<211>  8979
<212>  DNA
<213>  homo sapiens

<400>  222
agttgttagg agagaccatt ggggatagga aagatgaaag gtcatggtga gcttcaagga       60

catgaaaggt tgttgtctca tgtaacaata gtagattgtt ttttttccta atatttctag      120

ccagccccta agtcaggtga tggaacaaat acctacagtt tagtcaggtg aaacaggagt      180

gggtggagga aggaaagaag aaaaatggga agaatgtctt ccaagcaagc cacctctcca      240

tttgcctgtg cagctgatgg agaggatgca atgacccagg atttaacctc aagggaaaag      300

gaagagggca gtgatcaaca tgtggcctcc catctgcctc tgcaccccat aatgcacaac      360

aaacctcact ctgaggagct accaacactt gtcagtacca ttcaacaaga tgctgactgg      420

gacagcgttc tgtcatctca gcaaagaatg gaatcagaga ataataagtt atgttcccta      480

tattccttcc gaaatacctc tacctcacca cataagcctg acgaagggag tcgggaccgt      540

gagataatga ccagtgttac ttttggaacc ccagagcgcc gcaaagggag tcttgccgat      600

gtggtggaca cactgaaaca gaagaagctt gaggaaatga ctcggactga acaagaggat      660

tcctcctgca tggaaaaact actttcaaaa gattggaagg aaaaaatgga aagactaaat      720

accagtgaac ttcttggaga aattaaaggt acacctgaga gcctggcaga aaaagaacgg      780

cagctctcca ccatgattac ccagctgatc agtttacggg agcagctact ggcagcgcat      840

gatgaacaga aaaaactggc agcgtcacaa attgagaaac aacggcagca aatggacctt      900

gctcgccaac agcaagaaca gattgcgaga caacagcagc aacttctgca acagcagcac      960

aaaattaatc tcctgcagca acagatccag gttcagggtc acatgcctcc gctcatgatc     1020

ccaatttttc cacatgacca gcggactctg gcagcagctg ctgctgccca acagggattc     1080

ctcttccccc ctggaataac atacaaacca ggtgataact accccgtaca gttcattcca     1140

tcaacaatgg cagctgctgc tgcttctgga ctcagccctt tacagctcca gcagctctat     1200

gccgctcagc tggccagcat gcaggtgtca cctggagcaa agatgccatc aactccacag     1260

ccaccaaaca cagcagggac ggtctcacct actgggataa aaaatgaaaa gagagggacc     1320

agccctgtaa ctcaagttaa ggatgaagca gcagcacagc ctctgaatct ctcatcccga     1380

cccaagacag cagagcctgt aaagtcccca acgtctccca cccagaacct cttcccagcc     1440

agcaaaacca gccctgtcaa tctgccaaac aaaagcagca tccctagccc cattggagga     1500

agcctgggaa gaggatcctc tttaggtaaa tggaaaagtc aacaccagga agagacttac     1560

gaattagata tcctatctag tctcaactcc cctgcccttt ttggggatca ggatacagtg     1620

atgaaagcca ttcaggaggc gcggaagatg cgagagcaga tccagcggga gcaacagcag     1680

caacagccac atggtgttga cgggaaactg tcctccataa ataatatggg gctgaacagc     1740

tgcaggaatg aaaaggaaag aacgcgcttt gagaatttgg ggccccagtt aacgggaaag     1800

tcaaatgaag atggaaaact gggcccaggt gtcatcgacc ttactcggcc agaagatgca     1860

gagggaagta aagcaatgaa tggctctgca gctaaactac agcagtatta ttgttggcca     1920

acaggaggtg ccactgtggc tgaagcacga gtctacaggg acgcccgcgg ccgtgccagc     1980

agcgagccac acattaagcg accaatgaat gcattcatgg tttgggcaaa ggatgagagg     2040

agaaaaatcc ttcaggcctt ccccgacatg cataactcca acattagcaa aatcttagga     2100

tctcgctgga aatcaatgtc caaccaggag aagcaacctt attatgaaga gcaggcccgg     2160

ctaagcaaga tccacttaga gaagtaccca aactataaat acaaaccccg accgaaacgc     2220

acctgcattg ttgatggcaa aaagcttcgg attggggagt ataagcaact gatgaggtct     2280

cggagacagg agatgaggca gttctttact gtggggcaac agcctcagat tccaatcacc     2340

acaggaacag gtgttgtgta tcctggtgct atcactatgg caactaccac accatcgcct     2400

cagatgacat ctgactgctc tagcacctcg gccagcccgg agcccagcct cccggtcatc     2460

cagagcactt atggtatgaa gacagatggc ggaagcctag ctggaaatga aatgatcaat     2520

ggagaggatg aaatggaaat gtatgatgac tatgaagatg accccaaatc agactatagc     2580

agtgaaaatg aagccccgga ggctgtcagt gccaactgag gagtttttgt ttgctgaatt     2640

aaagtactct gacatttcac ccccctcccc aacaaagagt tattaaagag cccgcatgca     2700

tttgtggctc cacaattaca tcagcagaat ggtcttaatt gtttcgtaaa gtgtgagaca     2760

gattaagttt tccctgattt ttcatgaact tgagtttttt gttgttattg ttattgttgt     2820

tgttgttgtt tttttaattt aggtgaagac atattaaata tgagacacca ggacttgaaa     2880

cttatctcaa cccgtagatg tcttacaagt cttatatttt tgtcttactt tttttttctt     2940

ttggatgttg ataaaggttt aagttactgt tttagatggg gttaaacatt ctcactcagg     3000

tatgctgtgc cggcctacag gttgtgaatg tgtttttatt ctgaattatt ttagaaaaca     3060

actgaggatt tcatattgtg aaacagaaca agtccacggc gtgtgcagct gcatgtagag     3120

catattcaaa aggcctcgga attccaattt tccatttgta gagttaaact ttgaatgtgc     3180

caaacttttt cgtaactttt gaatcttaat attttgaaag tcttaaagga gacactgcaa     3240

agtcttagac aatctttggc atcttaaaat aaaatagcaa accaacattt ttttttccag     3300

aaaatggtaa ggtactcagg aatctggaga caagatattg taaggaatga acaaggttgc     3360

cacagtgcat ggacccaatt gtgtttgcct gttgacgtgc catcagtgcg tgatgtggta     3420

tgacatacac acaccagagc aaccgccaca ccagatatcg acagagtggt cttctctgcc     3480

tgagaccacc tctcactaca tccattatcc ctttgccttt aaccctgaca ttcagtctta     3540

acacatttta tcttaaataa tttattcatt ccagaatgtc aagggtccac ttgctattta     3600

ttttttttca attgttggtg gcattaattt aataattctt gtttttcacc ttccttcccc     3660

gaagaacttt tccgtccttt tcacctcctt ctcctgtgta catagtgatt ttatgtcccc     3720

agaacgcctg gaagcatttc tgaaaccaag atattattaa aaacctatta ttgtttttaa     3780

tcatgagtat gtatctggct gcagggctgt gtattgggat ataggtatat agtcttacac     3840

ttaaacaggt atgcccctga ggttcactgt gacctcaagt cttttgccag aattttcccc     3900

taattcagtt cacaagtggt agggtctgca tcagtggcat ttccccctga attccattca     3960

gcagcaaggt tcaacagtgg tgactgccag gcaggagagt cctgcggcca aacctgaagc     4020

ccaaggctcg tgggccatgc aggaatctca gtgaagctgt catgggctgg cacctttaca     4080

ctgagttgcc ttgtcccagc tggcacatct agggagttca ttgcaaaatc cccaggatgc     4140

aaaaagccac atgacagcct cagagcaaag atggtggcaa atagtcatga tacatctaga     4200

gaatgaaaga aaactgtaag ggaggagaag gaggggaata cattccctat atgggatgtt     4260

cctactgtta actctgggga acagatagct ccgggggcag cagatgagtt cctctggctg     4320

actctatctg tagccacatg gggacctgcc tacgtgtgaa caaaatgaac tgcacttatc     4380

acacaaggat ttctttgaag acatgctact ggggtgggaa gcagtgaggt tttattcccc     4440

atctcctaac tacagggagc tctgccatgt cattttggcc ttcctgaaac taggacaggt     4500

tgtctatcgg ggggcttccc ccagagaggt ttagtgggag aatgtcagtg aatgggatag     4560

ttcacctcat gggacaaccc agaatctgat caccaggaca taggaatggc cccatcagat     4620

ttcttgagcc attttgtcac ttggaagaaa atagtgtacc tttgtattta tttaagagtg     4680

ctcaaggcct aatagcaata aacaggtcta gccaagaaat tacaagctat tctgttagct     4740

gggagtgctc tctataagct gattaaggta ctgataggaa ctctttgtta ttcatgttgg     4800

ttggggatta gaaatttgtt tttgtacatt tatttcaaat gaggaggagg tcattttttc     4860

tctcaaaaaa tgagtattta ttattgtctt actgatttct ttgattatat acctctcctc     4920

ctcagttcac tcttgttttt tttctttctc tttggctttt gcttttgctc tctctcactt     4980

ctttcttatt ttgttgcatt ggtagagtgt tgtatggcta gcattgtatt gtatgtaatt     5040

aattttgcac aaaagcaaac atttagcata gtaggttaat tttgtttgtt tttatgacca     5100

tgccaaaata atattctggg ctggtggaga acaaaggact gttctttagg actgaaactt     5160

gattttgctc atagtaagta aaaaaaaaca aaaaacacac acactcacag atgttgtttc     5220

gtaagtgtta taagcactgg atataaatgg tattttttat cacttctgac taatgtgaaa     5280

ctgttgtacg aaaactacat gaacaaaagt catctgtttc gactcgtgtg ggcttgcctc     5340

acagttgccg gatttgagtc atttttatgt cttgttattt catttattta tgcaaaatac     5400

atgtgtgtat gaacactttg ttttagctcc agctctgcct cagtactggg gttcatttac     5460

ttttagccat gttcttaaaa atgaaaggct attcaggaat gatctgattg taaacgtctt     5520

tttcattgga tcaaacagta atgctgtatt tgaatctaaa ttttgtgtat aagcagttta     5580

tttattagcc aagtttggct ctaaatatcc atggaaatta agaatgacaa tcatagggat     5640

caattcattt tattttcagt ggggcttaaa caaagtttat atgactttac catctcattt     5700

tagatttttc taattgtgta aatataacat agaaatagaa tttatttttg gttcatgaat     5760

acttagtgag atataagtta tgtatttcct ttttgttctc tatccataga tgttggtcca     5820

aactgaaagt tgatgagtca ctgtgcctct cggggtagtg agttatcagc tacagtgaga     5880

gagcagtgtt tggcctgcag ctgggacagc aaaacgtttc accagggttc tcatgcagtt     5940

cagaacccac tgtccacaga tccagacatt tccctttttt cttacagaaa gttgatgatt     6000

ggacatacta aatttccact acagttagga gacagtcagt ttgctttggg agtctacata     6060

aatcttctaa gatagttctg tgaccattta atagcaagaa gcatgaatgc cactacaaag     6120

gcaaaaatcc acctctgaga tcggccgtta ataaacgtcc cgtcatgtca gtttagattc     6180

aagaatgtta agcaactttg tttttgcggt gctccctatt tcatagtatc ttcaaatcaa     6240

aaataaaaat tatctccatt ttgttaaaga acttacaggg tcagggttct ccttgtcact     6300

tagaattggg acactgccag gcaatcctct cccaaaaaaa aaaaaaaaaa aaaatagcca     6360

tatggaatgg aaggaaaagg agaaaagaag gaagaaagga aaaaagtagg aagggagaga     6420

gaaaaaaaag gtcgctttgc ggatacgagc cgctaggctg acaacttttc tatttcattg     6480

gcagatatga agcagtgtct tttccagtaa ggtacggaag ctttgttgtt ttcatgtgta     6540

cccagctcag ccttttagaa gcacctcggt ttgcttcatt aggtatttga tactctccag     6600

ccttgtcctc aggcctgatt tgatttgcca gggtcctgac accaaagccc aggccaagtt     6660

ctaaattcag gtgtgggctc acagtgctat tgagcttgtc gaattctggc ctcccctgaa     6720

cattagcccc acgggagcct gagggtgttt gaaaagggcg tgatcactct agggctgaaa     6780

ttaaaggctg ctttcttttc cttctgaagc caggctgctt cttcggagta caccctcctg     6840

agccaggagc acaagcacta gcagaaagca gggattgttt caggaaagcc catttaccct     6900

cagtaggaag gcagcctggt cacttgaaca gcacagctga ggctgcttct ctcaatttac     6960

tcattttgca aagaattgac ctctaccaac tcattaggga gaggaaaaag aatcacttag     7020

taattttaaa tcatatgaga agtcctgtac caagtgccaa caactgcaaa gaaatgcagc     7080

tagaggaatg tattgaaatt actactgggt cttccttttt aatgagaaaa tgacaaaaat     7140

ggttgctgta gccctgcctg attttgtaca cgtttgtcta agaattgagt tggcacttaa     7200

gctcacttct caaagtataa taatattgta tgacctcatt tgtcctttca caaaagcact     7260

tgcatcattt ccttaagtca tctgctccct gacatgtttt cttccctaat aaacaacttc     7320

tgtctgttat tcctgccaat gatgttctgt ttctgatgcc atatcctatt gagcgtgccc     7380

ctgtactaat atcattgaaa atattgatat gcaaacacat ttccttttca tccccattct     7440

atctttccct ttggggacag attgctttcc aaaagctcat gaacaaatat ttggaatgct     7500

ggtacctttg gggcagaggt aagggtgggc ggggtggggg cagaaaggta atgcttaatg     7560

cagataactc ttctaatcag tgtccatggc aatatgaacg cttgaagaaa actcagtgac     7620

atatcttgct cagtagtttc ttattcctga agaaccacaa gcataaagtg aggcctcagt     7680

gctggtgctc ttggagtatg gggaatgtgc aaatatttaa ctgttttgta tgctgcacat     7740

tgcaggtctg ctcatgtgca ttctcccttt gtcttccttt gtcatatgtg tttttgcttt     7800

tttgaaagtg cagtctttat tgtaccctcc tccagcttgt agcaaattag aatgcttagc     7860

atttatgttc attcattatt gtatttgcca tgtaaaattt ttattacctt agacaagctt     7920

ataagctgtt actacataac ttatcttact gtaactcttt tatttccccc gacgttgtaa     7980

tttgtttgtg atgtatattg tgaaattgta ttctatgtta atttaatcag cacaattcac     8040

tgacatgctg gactgacatg ctggctgctg tttcaaagtg taaagtttgt gtagggctgt     8100

tgggacaact gcaactctgt tgtcaaggta ctgtgctttg gttcctatag caacactggg     8160

tgtggccctt gaattgctaa gggcatttaa tacatcctgg agcaaatttt aactgcagat     8220

tttctttgta gaaattctat gtataatgca ggtacctact tggcccatgg ctggtaacta     8280

tttgggcaat tagaaaaaaa gaaaaaaaca taaaaactag tgtctattgc tgctttgaat     8340

atgtttgaaa gtctgaaaat gtaaatagtt tatcaaaaaa aaatcttgta cagtccagtg     8400

taaagttttt aaatgacctt aagggttgcc atcacatctt tctcacactc tcctcttgat     8460

aataataata ataaaaagtt tgctaaggat taaagaaatg ggaaaaataa aaaaaatctc     8520

ttcaaattta caggaatgaa tcattgttct tagctttgtt gcatacacaa acttcttgga     8580

ttttgttgtg cagtattgac gtgagataaa gctcaacatt gaataatctt tcagtggtac     8640

ttttcaaagt cttcccctcc tctgcctcat aattaaggga aaagacaaaa ttgaaagaca     8700

cactgtcttt atctatcctg gtgtatgttg gcaccttagc tacttttttt ttttcctttt     8760

tgcacaaggt gctttcctga tatgttcaac atgccatctt tgggtgataa tgtatatgcc     8820

gtgatggggc tcaggcccct taggggagtg tctataagaa ctgcctattt atgctcattt     8880

acctcaagac tgtcctctct accctaatct agttgtcatc actccatctt ttgtactgct     8940

gttgacactt acaaattaaa gataaatttt gttttatga                            8979


<210>  223
<211>  4078
<212>  DNA
<213>  homo sapiens

<400>  223
gaggaggagg ggacccgccg ccgggggctg gctgcttcgc tccgagccga cttttcgcca       60

atggtccaaa gggacatgtc caagtcgcct cccacagcgg cggcggcggt ggcgcaggag      120

atccagatgg aactgctaga gaacgtggct cccgcggggg cgctcggagc cgccgcacag      180

tcatatggaa aaggagccag aaggaaaaac agatttaaag gatctgatgg aagcacgtca      240

tctgatacta cctcaaatag ttttgttcgc cagggttcgg cagactccta cactagccgt      300

ccatccgatt ccgatgtatc tctggaggag gaccgggagg cagtgcgcag agaagcggag      360

cggcaggccc aggcacagtt ggaaaaagca aagacaaagc ccgttgcatt tgcggttcgg      420

acaaatgtca gctacagtgc ggcccatgaa gatgatgttc cagtgcctgg catggccatc      480

tcattcgaag caaaagattt tctgcatgtt aaggaaaaat ttaacaatga ctggtggata      540

gggcgattgg taaaagaagg ctgtgaaatc ggattcattc caagcccagt caaactagaa      600

aacatgaggc tgcagcatga acagagagcc aagcaaggga aattctactc cagtaaatca      660

ggaggaaatt catcatccag tttgggtgac atagtaccta gttccagaaa atcaacacct      720

ccatcatctg ctatagacat agatgctact ggcttagatg cagaagaaaa tgatattcca      780

gcaaaccacc gctcccctaa acccagtgca aacagtgtaa cgtcacccca ctccaaagag      840

aaaagaatgc ccttctttaa gaagacagag cacactcctc cgtatgatgt ggtaccttcc      900

atgcgaccag tggtcctagt gggcccttct ctgaagggct acgaggtcac agatatgatg      960

caaaaagcgc tgtttgattt tttaaaacac agatttgaag ggcggatatc catcacaagg     1020

gtcaccgctg acatctcgct tgccaaacgc tcggtattaa acaatcccag taagcacgca     1080

ataatagaaa gatccaacac aaggtcaagc ttagcggaag ttcagagtga aatcgaaagg     1140

atttttgaac ttgcaagaac attgcagttg gtggtccttg acgcggatac aattaatcat     1200

ccagctcaac tcagtaaaac ctccttggcc cctattatag tatatgtaaa gatttcttct     1260

cctaaggttt tacaaaggtt aataaaatct cgagggaaat ctcaagctaa acacctcaac     1320

gtccagatgg tagcagctga taaactggct cagtgtcctc cagagctgtt cgatgtgatc     1380

ttggatgaga accagcttga ggatgcctgt gagcaccttg ccgactatct ggaggcctac     1440

tggaaggcca cccatcctcc cagcagtagc ctccccaacc ctctccttag ccgtacatta     1500

gccacttcaa gtctgcctct tagccccacc ctagcctcta attcacaggg ttctcaaggt     1560

gatcagagga ctgatcgctc cgctcctatc cgttctgctt cccaagctga agaagaacct     1620

agtgtggaac cagtcaagaa atcccagcac cgctcttcct cctcagcccc acaccacaac     1680

catcgcagtg ggacaagtcg cggcctctcc aggcaagaga catttgactc ggaaacccag     1740

gagagtcgag actctgccta cgtagagcca aaggaagatt attcccatga ccacgtggac     1800

cactatgcct cacaccgtga ccacaaccac agagacgaga cccacgggag cagtgaccac     1860

agacacaggg agtcccggca ccgttcccgg gacgtggatc gagagcagga ccacaacgag     1920

tgcaacaagc agcgcagccg tcataaatcc aaggatcgct actgtgaaaa ggatggagaa     1980

gtgatatcaa aaaaacggaa tgaggctggg gagtggaaca gggatgttta catccgccaa     2040

tgagttttgc ccgtttgtgt tttttttttt ttttttttga agtcttgtat aactaacagc     2100

atccccaaaa caaagtcttt ggggtctaca ctgcaatcat atgtgatctg tcttgtaata     2160

ttttgtatta ttgctgttgc ttgaatagca atagcatgga tagagtattg agatactttt     2220

tcttttgtaa gtgctacata aattggcctg gtatggctgc agtcctccgg ttgcatactg     2280

gactcttcaa aaactgtttt gggtagctgc cacttgaaca aaatctgttg ccacccaggt     2340

gatgttagtg ttttaagaaa tgtagttgat gtatccaaca agccagaatc agcacagata     2400

aaaagtggaa tttcttgttt ctccagattt ttaatacgtt aatacgcagg catctgattt     2460

gcatattcat tcatggacca ctgtttcttg cttgtacctc tggctgacta aatttgggga     2520

cagattcagt cttgccttac acaaagggga tcataaagtt agaatctatt ttctatgtac     2580

tagtactgtg tactgtatag acagtttgta aatgttattt ctgcaaacaa acaccttctt     2640

attatatata taatatatat atatatcagt ttgatcacac tattttagag tcttaatgcc     2700

aagtcagcag atttgcttta tgaattacag ggactagaaa tgcccacatt caggaaattt     2760

gtaataacat tgtctagaca cctatcctca ttctagtaga aagtgtgtac atactgtaaa     2820

tatgtgtgat tgcttgactt gaaaaggttt gaattctgaa tgttatacca tccttgtaag     2880

taagtttgta atttccacca taaattatgg taaatataaa actccagagg ttgttctact     2940

ccatacagtt cacactgatt gtgacacatt cttagtagct agtgtctgtt ctagtcactg     3000

cactggagtc tacgagccgg aactcgctat atgcacgtgt gtgtgtccgt atgtaagaaa     3060

gtgtgcaccg agtgactgaa tggttgagat gaattggaat gctgaagact aacgaagaaa     3120

ctagagactg atatcgagca ttctgcccac ctcgctctgt atttaattaa ttgtgctata     3180

tgttgcttta acaacccatt gagcagtcag ggaatgtgag taagcttgct gccaaaggta     3240

actaggaaag cattcatctg ctgcctcctt gtttttgctc ctagagagtg aaaatacagg     3300

caattttact gtgagtgttt cactggaaat gtacaatctt tgtgtgttag agtatttgtt     3360

ttagtaagaa atgtttacac agcttgtgga attatttcgt gggaaaataa atttttataa     3420

cttctcccac ttcaatttct aaccttgcct attgttcctg ttgtttgttt acctcccagt     3480

tacctaccat tcctccccac caccgactcc agcaggttca ctgtctgtca gaacccagaa     3540

gtgcttctta taaccaaagt ttctgttctt cagaagaaat cagggcaaaa tggggtgact     3600

tgaagtgaat aaaatgttaa gaatattatc ctacataaga catgtacaca gaaggggaac     3660

cttgaagaca ttatctccat gcctcaatta cactgctgta agaagcttac aatgtcatca     3720

tgtttaaggc taagaccttt tccgtgtctc aagtgtatat tttgtccagt tataactgga     3780

tggtaagaca gtattaagag tgcaagtacc tggcacttga agtttgtccc aggaaaatgc     3840

ctgtgtataa ttacctaact tcagatctgc acattaactt atttaacaaa ataaatcagc     3900

cgggcgcagt ggctcatgcc tgtaatccca gcaatttggg aggctgagga gggtggatca     3960

cctgaggtca ggagttcaag accagcctgg ccaacgtggc gaaaccccgt ctctactaaa     4020

aagataaaaa attagccagg tgtggtggtg cacacctgta atcccagcta cttgggag       4078


<210>  224
<211>  3964
<212>  DNA
<213>  homo sapiens

<400>  224
gaggaggagg ggacccgccg ccgggggctg gctgcttcgc tccgagccga cttttcgcca       60

atggtccaaa gggacatgtc caagtcgcct cccacagcgg cggcggcggt ggcgcaggag      120

atccagatgg aactgctaga gaacgtggct cccgcggggg cgctcggagc cgccgcacag      180

tcatatggaa aaggagccag aaggaaaaac agatttaaag gatctgatgg aagcacgtca      240

tctgatacta cctcaaatag ttttgttcgc cagggttcgg cagactccta cactagccgt      300

ccatccgatt ccgatgtatc tctggaggag gaccgggagg cagtgcgcag agaagcggag      360

cggcaggccc aggcacagtt ggaaaaagca aagacaaagc ccgttgcatt tgcggttcgg      420

acaaatgtca gctacagtgc ggcccatgaa gatgatgttc cagtgcctgg catggccatc      480

tcattcgaag caaaagattt tctgcatgtt aaggaaaaat ttaacaatga ctggtggata      540

gggcgattgg taaaagaagg ctgtgaaatc ggattcattc caagcccagt caaactagaa      600

aacatgaggc tgcagcatga acagagagcc aagcaaggga aattctactc cagtaaatca      660

ggaggaaatt catcatccag tttgggtgac atagtaccta gttccagaaa atcaacacct      720

ccatcatctg ctaagcagaa gcagaaatcg acagagcaca ctcctccgta tgatgtggta      780

ccttccatgc gaccagtggt cctagtgggc ccttctctga agggctacga ggtcacagat      840

atgatgcaaa aagcgctgtt tgatttttta aaacacagat ttgaagggcg gatatccatc      900

acaagggtca ccgctgacat ctcgcttgcc aaacgctcgg tattaaacaa tcccagtaag      960

cacgcaataa tagaaagatc caacacaagg tcaagcttag cggaagttca gagtgaaatc     1020

gaaaggattt ttgaacttgc aagaacattg cagttggtgg tccttgacgc ggatacaatt     1080

aatcatccag ctcaactcag taaaacctcc ttggccccta ttatagtata tgtaaagatt     1140

tcttctccta aggttttaca aaggttaata aaatctcgag ggaaatctca agctaaacac     1200

ctcaacgtcc agatggtagc agctgataaa ctggctcagt gtcctccaga gctgttcgat     1260

gtgatcttgg atgagaacca gcttgaggat gcctgtgagc accttgccga ctatctggag     1320

gcctactgga aggccaccca tcctcccagc agtagcctcc ccaaccctct ccttagccgt     1380

acattagcca cttcaagtct gcctcttagc cccaccctag cctctaattc acagggttct     1440

caaggtgatc agaggactga tcgctccgct cctatccgtt ctgcttccca agctgaagaa     1500

gaacctagtg tggaaccagt caagaaatcc cagcaccgct cttcctcctc agccccacac     1560

cacaaccatc gcagtgggac aagtcgcggc ctctccaggc aagagacatt tgactcggaa     1620

acccaggaga gtcgagactc tgcctacgta gagccaaagg aagattattc ccatgaccac     1680

gtggaccact atgcctcaca ccgtgaccac aaccacagag acgagaccca cgggagcagt     1740

gaccacagac acagggagtc ccggcaccgt tcccgggacg tggatcgaga gcaggaccac     1800

aacgagtgca acaagcagcg cagccgtcat aaatccaagg atcgctactg tgaaaaggat     1860

ggagaagtga tatcaaaaaa acggaatgag gctggggagt ggaacaggga tgtttacatc     1920

cgccaatgag ttttgcccgt ttgtgttttt tttttttttt ttttgaagtc ttgtataact     1980

aacagcatcc ccaaaacaaa gtctttgggg tctacactgc aatcatatgt gatctgtctt     2040

gtaatatttt gtattattgc tgttgcttga atagcaatag catggataga gtattgagat     2100

actttttctt ttgtaagtgc tacataaatt ggcctggtat ggctgcagtc ctccggttgc     2160

atactggact cttcaaaaac tgttttgggt agctgccact tgaacaaaat ctgttgccac     2220

ccaggtgatg ttagtgtttt aagaaatgta gttgatgtat ccaacaagcc agaatcagca     2280

cagataaaaa gtggaatttc ttgtttctcc agatttttaa tacgttaata cgcaggcatc     2340

tgatttgcat attcattcat ggaccactgt ttcttgcttg tacctctggc tgactaaatt     2400

tggggacaga ttcagtcttg ccttacacaa aggggatcat aaagttagaa tctattttct     2460

atgtactagt actgtgtact gtatagacag tttgtaaatg ttatttctgc aaacaaacac     2520

cttcttatta tatatataat atatatatat atcagtttga tcacactatt ttagagtctt     2580

aatgccaagt cagcagattt gctttatgaa ttacagggac tagaaatgcc cacattcagg     2640

aaatttgtaa taacattgtc tagacaccta tcctcattct agtagaaagt gtgtacatac     2700

tgtaaatatg tgtgattgct tgacttgaaa aggtttgaat tctgaatgtt ataccatcct     2760

tgtaagtaag tttgtaattt ccaccataaa ttatggtaaa tataaaactc cagaggttgt     2820

tctactccat acagttcaca ctgattgtga cacattctta gtagctagtg tctgttctag     2880

tcactgcact ggagtctacg agccggaact cgctatatgc acgtgtgtgt gtccgtatgt     2940

aagaaagtgt gcaccgagtg actgaatggt tgagatgaat tggaatgctg aagactaacg     3000

aagaaactag agactgatat cgagcattct gcccacctcg ctctgtattt aattaattgt     3060

gctatatgtt gctttaacaa cccattgagc agtcagggaa tgtgagtaag cttgctgcca     3120

aaggtaacta ggaaagcatt catctgctgc ctccttgttt ttgctcctag agagtgaaaa     3180

tacaggcaat tttactgtga gtgtttcact ggaaatgtac aatctttgtg tgttagagta     3240

tttgttttag taagaaatgt ttacacagct tgtggaatta tttcgtggga aaataaattt     3300

ttataacttc tcccacttca atttctaacc ttgcctattg ttcctgttgt ttgtttacct     3360

cccagttacc taccattcct ccccaccacc gactccagca ggttcactgt ctgtcagaac     3420

ccagaagtgc ttcttataac caaagtttct gttcttcaga agaaatcagg gcaaaatggg     3480

gtgacttgaa gtgaataaaa tgttaagaat attatcctac ataagacatg tacacagaag     3540

gggaaccttg aagacattat ctccatgcct caattacact gctgtaagaa gcttacaatg     3600

tcatcatgtt taaggctaag accttttccg tgtctcaagt gtatattttg tccagttata     3660

actggatggt aagacagtat taagagtgca agtacctggc acttgaagtt tgtcccagga     3720

aaatgcctgt gtataattac ctaacttcag atctgcacat taacttattt aacaaaataa     3780

atcagccggg cgcagtggct catgcctgta atcccagcaa tttgggaggc tgaggagggt     3840

ggatcacctg aggtcaggag ttcaagacca gcctggccaa cgtggcgaaa ccccgtctct     3900

actaaaaaga taaaaaatta gccaggtgtg gtggtgcaca cctgtaatcc cagctacttg     3960

ggag                                                                  3964


<210>  225
<211>  4098
<212>  DNA
<213>  homo sapiens

<400>  225
gactttgatg agctcctctg ctctgcctaa gtggttctgg aacagagagc tgttgtgatc       60

cgacgaactt tagaaagtca cactaactaa gactacacac cccaagccag caagaaaaag      120

gaaagcagtt gctatgctgt tcagcaaagc aagacttggc tgccttttag ctagtcctga      180

attcttgctc ctgtgaagaa aattcctgct ggagtgctgg gcgcacttgg aattggtcta      240

gcatgcttga cagacgcctt atagctcctc aaactaaata cattattcct gggggttcgg      300

cagactccta cactagccgt ccatccgatt ccgatgtatc tctggaggag gaccgggagg      360

cagtgcgcag agaagcggag cggcaggccc aggcacagtt ggaaaaagca aagacaaagc      420

ccgttgcatt tgcggttcgg acaaatgtca gctacagtgc ggcccatgaa gatgatgttc      480

cagtgcctgg catggccatc tcattcgaag caaaagattt tctgcatgtt aaggaaaaat      540

ttaacaatga ctggtggata gggcgattgg taaaagaagg ctgtgaaatc ggattcattc      600

caagcccagt caaactagaa aacatgaggc tgcagcatga acagagagcc aagcaaggga      660

aattctactc cagtaaatca ggaggaaatt catcatccag tttgggtgac atagtaccta      720

gttccagaaa atcaacacct ccatcatctg ctatagacat agatgctact ggcttagatg      780

cagaagaaaa tgatattcca gcaaaccacc gctcccctaa acccagtgca aacagtgtaa      840

cgtcacccca ctccaaagag aaaagaatgc ccttctttaa gaagacagag cacactcctc      900

cgtatgatgt ggtaccttcc atgcgaccag tggtcctagt gggcccttct ctgaagggct      960

acgaggtcac agatatgatg caaaaagcgc tgtttgattt tttaaaacac agatttgaag     1020

ggcggatatc catcacaagg gtcaccgctg acatctcgct tgccaaacgc tcggtattaa     1080

acaatcccag taagcacgca ataatagaaa gatccaacac aaggtcaagc ttagcggaag     1140

ttcagagtga aatcgaaagg atttttgaac ttgcaagaac attgcagttg gtggtccttg     1200

acgcggatac aattaatcat ccagctcaac tcagtaaaac ctccttggcc cctattatag     1260

tatatgtaaa gatttcttct cctaaggttt tacaaaggtt aataaaatct cgagggaaat     1320

ctcaagctaa acacctcaac gtccagatgg tagcagctga taaactggct cagtgtcctc     1380

cagagctgtt cgatgtgatc ttggatgaga accagcttga ggatgcctgt gagcaccttg     1440

ccgactatct ggaggcctac tggaaggcca cccatcctcc cagcagtagc ctccccaacc     1500

ctctccttag ccgtacatta gccacttcaa gtctgcctct tagccccacc ctagcctcta     1560

attcacaggg ttctcaaggt gatcagagga ctgatcgctc cgctcctatc cgttctgctt     1620

cccaagctga agaagaacct agtgtggaac cagtcaagaa atcccagcac cgctcttcct     1680

cctcagcccc acaccacaac catcgcagtg ggacaagtcg cggcctctcc aggcaagaga     1740

catttgactc ggaaacccag gagagtcgag actctgccta cgtagagcca aaggaagatt     1800

attcccatga ccacgtggac cactatgcct cacaccgtga ccacaaccac agagacgaga     1860

cccacgggag cagtgaccac agacacaggg agtcccggca ccgttcccgg gacgtggatc     1920

gagagcagga ccacaacgag tgcaacaagc agcgcagccg tcataaatcc aaggatcgct     1980

actgtgaaaa ggatggagaa gtgatatcaa aaaaacggaa tgaggctggg gagtggaaca     2040

gggatgttta catccgccaa tgagttttgc ccgtttgtgt tttttttttt ttttttttga     2100

agtcttgtat aactaacagc atccccaaaa caaagtcttt ggggtctaca ctgcaatcat     2160

atgtgatctg tcttgtaata ttttgtatta ttgctgttgc ttgaatagca atagcatgga     2220

tagagtattg agatactttt tcttttgtaa gtgctacata aattggcctg gtatggctgc     2280

agtcctccgg ttgcatactg gactcttcaa aaactgtttt gggtagctgc cacttgaaca     2340

aaatctgttg ccacccaggt gatgttagtg ttttaagaaa tgtagttgat gtatccaaca     2400

agccagaatc agcacagata aaaagtggaa tttcttgttt ctccagattt ttaatacgtt     2460

aatacgcagg catctgattt gcatattcat tcatggacca ctgtttcttg cttgtacctc     2520

tggctgacta aatttgggga cagattcagt cttgccttac acaaagggga tcataaagtt     2580

agaatctatt ttctatgtac tagtactgtg tactgtatag acagtttgta aatgttattt     2640

ctgcaaacaa acaccttctt attatatata taatatatat atatatcagt ttgatcacac     2700

tattttagag tcttaatgcc aagtcagcag atttgcttta tgaattacag ggactagaaa     2760

tgcccacatt caggaaattt gtaataacat tgtctagaca cctatcctca ttctagtaga     2820

aagtgtgtac atactgtaaa tatgtgtgat tgcttgactt gaaaaggttt gaattctgaa     2880

tgttatacca tccttgtaag taagtttgta atttccacca taaattatgg taaatataaa     2940

actccagagg ttgttctact ccatacagtt cacactgatt gtgacacatt cttagtagct     3000

agtgtctgtt ctagtcactg cactggagtc tacgagccgg aactcgctat atgcacgtgt     3060

gtgtgtccgt atgtaagaaa gtgtgcaccg agtgactgaa tggttgagat gaattggaat     3120

gctgaagact aacgaagaaa ctagagactg atatcgagca ttctgcccac ctcgctctgt     3180

atttaattaa ttgtgctata tgttgcttta acaacccatt gagcagtcag ggaatgtgag     3240

taagcttgct gccaaaggta actaggaaag cattcatctg ctgcctcctt gtttttgctc     3300

ctagagagtg aaaatacagg caattttact gtgagtgttt cactggaaat gtacaatctt     3360

tgtgtgttag agtatttgtt ttagtaagaa atgtttacac agcttgtgga attatttcgt     3420

gggaaaataa atttttataa cttctcccac ttcaatttct aaccttgcct attgttcctg     3480

ttgtttgttt acctcccagt tacctaccat tcctccccac caccgactcc agcaggttca     3540

ctgtctgtca gaacccagaa gtgcttctta taaccaaagt ttctgttctt cagaagaaat     3600

cagggcaaaa tggggtgact tgaagtgaat aaaatgttaa gaatattatc ctacataaga     3660

catgtacaca gaaggggaac cttgaagaca ttatctccat gcctcaatta cactgctgta     3720

agaagcttac aatgtcatca tgtttaaggc taagaccttt tccgtgtctc aagtgtatat     3780

tttgtccagt tataactgga tggtaagaca gtattaagag tgcaagtacc tggcacttga     3840

agtttgtccc aggaaaatgc ctgtgtataa ttacctaact tcagatctgc acattaactt     3900

atttaacaaa ataaatcagc cgggcgcagt ggctcatgcc tgtaatccca gcaatttggg     3960

aggctgagga gggtggatca cctgaggtca ggagttcaag accagcctgg ccaacgtggc     4020

gaaaccccgt ctctactaaa aagataaaaa attagccagg tgtggtggtg cacacctgta     4080

atcccagcta cttgggag                                                   4098


<210>  226
<211>  4006
<212>  DNA
<213>  homo sapiens

<400>  226
gaggaggagg ggacccgccg ccgggggctg gctgcttcgc tccgagccga cttttcgcca       60

atggtccaaa gggacatgtc caagtcgcct cccacagcgg cggcggcggt ggcgcaggag      120

atccagatgg aactgctaga gaacgtggct cccgcggggg cgctcggagc cgccgcacag      180

tcatatggaa aaggagccag aaggaaaaac agatttaaag gatctgatgg aagcacgtca      240

tctgatacta cctcaaatag ttttgttcgc cagggttcgg cagactccta cactagccgt      300

ccatccgatt ccgatgtatc tctggaggag gaccgggagg cagtgcgcag agaagcggag      360

cggcaggccc aggcacagtt ggaaaaagca aagacaaagc ccgttgcatt tgcggttcgg      420

acaaatgtca gctacagtgc ggcccatgaa gatgatgttc cagtgcctgg catggccatc      480

tcattcgaag caaaagattt tctgcatgtt aaggaaaaat ttaacaatga ctggtggata      540

gggcgattgg taaaagaagg ctgtgaaatc ggattcattc caagcccagt caaactagaa      600

aacatgaggc tgcagcatga acagagagcc aagcaaggga aattctactc cagtaaatca      660

ggaggaaatt catcatccag tttgggtgac atagtaccta gttccagaaa atcaacacct      720

ccatcatctg gtgcaaaatc tgcagatgaa caagaccagt ggaaaactgc aggcttgttt      780

tggcggttta ctacagagca cactcctccg tatgatgtgg taccttccat gcgaccagtg      840

gtcctagtgg gcccttctct gaagggctac gaggtcacag atatgatgca aaaagcgctg      900

tttgattttt taaaacacag atttgaaggg cggatatcca tcacaagggt caccgctgac      960

atctcgcttg ccaaacgctc ggtattaaac aatcccagta agcacgcaat aatagaaaga     1020

tccaacacaa ggtcaagctt agcggaagtt cagagtgaaa tcgaaaggat ttttgaactt     1080

gcaagaacat tgcagttggt ggtccttgac gcggatacaa ttaatcatcc agctcaactc     1140

agtaaaacct ccttggcccc tattatagta tatgtaaaga tttcttctcc taaggtttta     1200

caaaggttaa taaaatctcg agggaaatct caagctaaac acctcaacgt ccagatggta     1260

gcagctgata aactggctca gtgtcctcca gagctgttcg atgtgatctt ggatgagaac     1320

cagcttgagg atgcctgtga gcaccttgcc gactatctgg aggcctactg gaaggccacc     1380

catcctccca gcagtagcct ccccaaccct ctccttagcc gtacattagc cacttcaagt     1440

ctgcctctta gccccaccct agcctctaat tcacagggtt ctcaaggtga tcagaggact     1500

gatcgctccg ctcctatccg ttctgcttcc caagctgaag aagaacctag tgtggaacca     1560

gtcaagaaat cccagcaccg ctcttcctcc tcagccccac accacaacca tcgcagtggg     1620

acaagtcgcg gcctctccag gcaagagaca tttgactcgg aaacccagga gagtcgagac     1680

tctgcctacg tagagccaaa ggaagattat tcccatgacc acgtggacca ctatgcctca     1740

caccgtgacc acaaccacag agacgagacc cacgggagca gtgaccacag acacagggag     1800

tcccggcacc gttcccggga cgtggatcga gagcaggacc acaacgagtg caacaagcag     1860

cgcagccgtc ataaatccaa ggatcgctac tgtgaaaagg atggagaagt gatatcaaaa     1920

aaacggaatg aggctgggga gtggaacagg gatgtttaca tccgccaatg agttttgccc     1980

gtttgtgttt tttttttttt ttttttgaag tcttgtataa ctaacagcat ccccaaaaca     2040

aagtctttgg ggtctacact gcaatcatat gtgatctgtc ttgtaatatt ttgtattatt     2100

gctgttgctt gaatagcaat agcatggata gagtattgag atactttttc ttttgtaagt     2160

gctacataaa ttggcctggt atggctgcag tcctccggtt gcatactgga ctcttcaaaa     2220

actgttttgg gtagctgcca cttgaacaaa atctgttgcc acccaggtga tgttagtgtt     2280

ttaagaaatg tagttgatgt atccaacaag ccagaatcag cacagataaa aagtggaatt     2340

tcttgtttct ccagattttt aatacgttaa tacgcaggca tctgatttgc atattcattc     2400

atggaccact gtttcttgct tgtacctctg gctgactaaa tttggggaca gattcagtct     2460

tgccttacac aaaggggatc ataaagttag aatctatttt ctatgtacta gtactgtgta     2520

ctgtatagac agtttgtaaa tgttatttct gcaaacaaac accttcttat tatatatata     2580

atatatatat atatcagttt gatcacacta ttttagagtc ttaatgccaa gtcagcagat     2640

ttgctttatg aattacaggg actagaaatg cccacattca ggaaatttgt aataacattg     2700

tctagacacc tatcctcatt ctagtagaaa gtgtgtacat actgtaaata tgtgtgattg     2760

cttgacttga aaaggtttga attctgaatg ttataccatc cttgtaagta agtttgtaat     2820

ttccaccata aattatggta aatataaaac tccagaggtt gttctactcc atacagttca     2880

cactgattgt gacacattct tagtagctag tgtctgttct agtcactgca ctggagtcta     2940

cgagccggaa ctcgctatat gcacgtgtgt gtgtccgtat gtaagaaagt gtgcaccgag     3000

tgactgaatg gttgagatga attggaatgc tgaagactaa cgaagaaact agagactgat     3060

atcgagcatt ctgcccacct cgctctgtat ttaattaatt gtgctatatg ttgctttaac     3120

aacccattga gcagtcaggg aatgtgagta agcttgctgc caaaggtaac taggaaagca     3180

ttcatctgct gcctccttgt ttttgctcct agagagtgaa aatacaggca attttactgt     3240

gagtgtttca ctggaaatgt acaatctttg tgtgttagag tatttgtttt agtaagaaat     3300

gtttacacag cttgtggaat tatttcgtgg gaaaataaat ttttataact tctcccactt     3360

caatttctaa ccttgcctat tgttcctgtt gtttgtttac ctcccagtta cctaccattc     3420

ctccccacca ccgactccag caggttcact gtctgtcaga acccagaagt gcttcttata     3480

accaaagttt ctgttcttca gaagaaatca gggcaaaatg gggtgacttg aagtgaataa     3540

aatgttaaga atattatcct acataagaca tgtacacaga aggggaacct tgaagacatt     3600

atctccatgc ctcaattaca ctgctgtaag aagcttacaa tgtcatcatg tttaaggcta     3660

agaccttttc cgtgtctcaa gtgtatattt tgtccagtta taactggatg gtaagacagt     3720

attaagagtg caagtacctg gcacttgaag tttgtcccag gaaaatgcct gtgtataatt     3780

acctaacttc agatctgcac attaacttat ttaacaaaat aaatcagccg ggcgcagtgg     3840

ctcatgcctg taatcccagc aatttgggag gctgaggagg gtggatcacc tgaggtcagg     3900

agttcaagac cagcctggcc aacgtggcga aaccccgtct ctactaaaaa gataaaaaat     3960

tagccaggtg tggtggtgca cacctgtaat cccagctact tgggag                    4006


<210>  227
<211>  2794
<212>  DNA
<213>  homo sapiens

<400>  227
tgattgaggt gcagagcaaa gtgaagggct gcccaggtga ggccaggctg actgaaaaag       60

atggatacta ctatgctgaa tatgcggaat ctgtttgagc agcttgtgcg cggggcggag      120

attctcaagg aaggaaacga actccaattt atccagttgg tgaaggactt tgaggatttc      180

tttaaaaagt gggagaggac tgactatgag ctggggaaat acaaggatct tttgataaaa      240

gcagagactg agtgaagtgc tctggatgtt aagctgaagc atgcacataa tcaggtggat      300

gcagacatcc aaacggagag ctgaggctaa ctgcgaaaag ctggagtaac agattcagct      360

gattggagag atgttcctgt gtgacatatc tggcagcatt caactaagcg gggagcaaaa      420

atcagctttg gcttttctca acagaggcca accatccagc agcaatgctg ggaacaaaag      480

actttaaatt agcgatgaat ctggttccat tttatcaggt atcagctttg acaagactga      540

tgaatcactg gattgcgact cttctttggt gaagactttc aagcggaagc agagagaaaa      600

gaggtgctct agtagccgac agtttgttga tggtccctct ggacctgtaa aggaaactcg      660

ttccattggc tccacagtag accaggggga atgaatccat agttgcaaaa actacagtga      720

ctgttcccaa ggatggcggg cccatcaaag ctgtgcccac tattgagact gtgccatact      780

ggaccaggag ccaaaggaaa acaggtactt tacaaccttg gaacagtgac cccaccctga      840

acagcaggca gctggagcca agaactgaga caatgtgggc acgccacaga gtaacagagg      900

gatgtgcctg aatgactttg tctctaagac ggttattaaa cctgaattct atgttccatg      960

tggaaagcag ataaaatttg ggaaactatc tctgaagtgt caggactgtt gtgtgatctc     1020

tcgtccagaa tgtcgggacc actgtcccct tccctgcatt cctaccctga taggaacacc     1080

tgtcaagatt ggagagggaa tgctggccga ctttgtgtcc cagacttttc caatgatccc     1140

ccgcattgtt gtgcattgtg taaatgagat tgagcagaga ggtcttactg agacaggcct     1200

gtataggatc ttgggctgtg acagcacagt aaaagctgaa agagaaattc ctcagagtga     1260

aaactgtacc cctcgtcagc aaagtggatg atatccatgc tatctgtagc cttcttaaag     1320

actttcttcg aaacttcaaa gaacctcttc tgacctttcg cctaaacaaa gcctttatgg     1380

aagcagcaga aatcacagat gaagacaaca gcatatctgc catgtaccag gctgttggtg     1440

aactgcccca ggccaacagg gacacattgg ttttcctcat gattcacttg cagagagtgg     1500

ctcagagtcc atatactaaa atgaatgttg ccaatctggc tgaagtcttt ggctctacaa     1560

tagtggccca tgctgtgccc aatccagaac cagtgacgat gttacaggac atcaagtgtc     1620

aacccaaggt ggtcgagcgc ctgccttcct tgcccctgga gtactggagt cagttctcaa     1680

tagtggagca gagaacattg accccctaca tgtcactgaa aactcaaatg ccttttcaac     1740

accagatatt aaagtgagtt tactgggacc tgtgaccact cctgatcatc agcttctcaa     1800

gactccttca tctagttccc tgtcacaggg agtctgttcc accctcacaa agaacactcc     1860

cagatttggg agcaaaggca agtctgccac taacctagga aggcaaggca acctttttgc     1920

ttcttcaatg ctcaagtgaa gtcacatcta cctattactc ccagcattga ttgactataa     1980

gaaaggatgc acctgtactc tctgctctac agcctcctct tctcattact atttttagca     2040

ttctccaggc ttttactcaa gtttaatttt gcatgagggt tttactaaaa ttttatatat     2100

ctccccttcc ttctcctcga gtcacataat atcagtacct tgttctggtc actgttggga     2160

gcttttagat gagacatctt tccaggagta gaagggttag tatggaattg attgtgattc     2220

ttttggggga agggggttac tatccctttg gcttaaagcc aaatgctgct catggaatga     2280

acgatctttc tctagtttca ttcaactgat ttccatgaga caatgacaga aaccctacct     2340

atctgataag attggcttgt ctcagggtgg gaagtgggag ggtggggcga agaaaggatt     2400

acaccagaag atttaggatg cctccttcta agaactggaa gttctcattc cccattatga     2460

actgagctat aatatggagc tttcataaaa atgggatgca ttgaggacag aactagtgat     2520

gggagtatgt gtagctttga tttggatgat taggtcttta atagtgttga gtggcacaac     2580

cttgtaaatg tgaaagtaca acgcatattt atctctgatg tgccattggc tgaaccttgg     2640

gttaatttgg ggtcaaagtc agtttttctt ttaaaattga attcattctg atgcttgacc     2700

cccatactcc caaccttgtc cagtggagcc caacttccaa aggtcaatat gtcgtccttt     2760

ggcatcccaa ctaacaataa agaataggct ataa                                 2794


<210>  228
<211>  3315
<212>  DNA
<213>  homo sapiens

<400>  228
aataaatttc tctgtgattg gttggtgaag gttttcaaac cggagctgtg ggcgcggcgc       60

tgctctgccg ttgggtgagg cgcggagcga agtgaagggt ggcccaggtg gggccaggct      120

gactgaatgt atctcctagc tatggactaa ataatacatg gggggaaata aacaagtatt      180

catgagggtg aaaatgtgac ccagcaggaa aattacaact attttcaatt gacgttgaat      240

aggatgagtc atggaattta agtgatttac tgaagattat actactggta gatagaagag      300

ctaaagaaag atggatacta tgatgctgaa tgtgcggaat ctgtttgagc agcttgtgcg      360

ccgggtggag attctcagtg aaggaaatga agtccaattt atccagttgg cgaaggactt      420

tgaggatttc cgtaaaaagt ggcagaggac tgaccatgag ctggggaaat acaaggatct      480

tttgatgaaa gcagagactg agcgaagtgc tctggatgtt aagctgaagc atgcacgtaa      540

tcaggtggat gtagagatca aacggagaca gagagctgag gctgactgcg aaaagctgga      600

acgacagatt cagctgattc gagagatgct catgtgtgac acatctggca gcattcaact      660

aagcgaggag caaaaatcag ctctggcttt tctcaacaga ggccaaccat ccagcagcaa      720

tgctgggaac aaaagactat caaccattga tgaatctggt tccattttat cagatatcag      780

ctttgacaag actgatgaat cactggattg ggactcttct ttggtgaaga ctttcaaact      840

gaagaagaga gaaaagaggc gctctactag ccgacagttt gttgatggtc cccctggacc      900

tgtaaagaaa actcgttcca ttggctctgc agtagaccag gggaatgaat ccatagttgc      960

aaaaactaca gtgactgttc ccaatgatgg cgggcccatc gaagctgtgt ccactattga     1020

gactgtgcca tattggacca ggagccgaag gaaaacaggt actttacaac cttggaacag     1080

tgactccacc ctgaacagca ggcagctgga gccaagaact gagacagaca gtgtgggcac     1140

gccacagagt aatggaggga tgcgcctgca tgactttgtt tctaagacgg ttattaaacc     1200

tgaatcctgt gttccatgtg gaaagcggat aaaatttggc aaattatctc tgaagtgtcg     1260

agactgtcgt gtggtctctc atccagaatg tcgggaccgc tgtccccttc cctgcattcc     1320

taccctgata ggaacacctg tcaagattgg agagggaatg ctggcagact ttgtgtccca     1380

gacttctcca atgatcccct ccattgttgt gcattgtgta aatgagattg agcaaagagg     1440

tctgactgag acaggcctgt ataggatctc tggctgtgac cgcacagtaa aagagctgaa     1500

agagaaattc ctcagagtga aaactgtacc cctcctcagc aaagtggatg atatccatgc     1560

tatctgtagc cttctaaaag actttcttcg aaacctcaaa gaacctcttc tgacctttcg     1620

ccttaacaga gcctttatgg aagcagcaga aatcacagat gaagacaaca gcatagctgc     1680

catgtaccaa gctgttggtg aactgcccca ggccaacagg gacacattag ctttcctcat     1740

gattcacttg cagagagtgg ctcagagtcc acatactaaa atggatgttg ccaatctggc     1800

taaagtcttt ggccctacaa tagtggccca tgctgtgccc aatccagacc cagtgacaat     1860

gttacaggac atcaagcgtc aacccaaggt ggttgagcgc ctgctttcct tgcctctgga     1920

gtattggagt cagttcatga tggtggagca agagaacatt gaccccctac atgtcattga     1980

aaactcaaat gccttttcaa caccacagac accagatatt aaagtgagtt tactgggacc     2040

tgtgaccact cctgaacatc agcttctcaa gactccttca tctagttccc tgtcacagag     2100

agtccgttcc accctcacca agaacactcc tagatttggg agcaaaagca agtctgccac     2160

taacctagga cgacaaggca acttttttgc ttctccaatg ctcaagtgaa gtcacatctg     2220

cctgttactt cccagcattg actgactata agaaaggaca catctgtact ctgctctgca     2280

gcctcctgta ctcattacta cttttagcat tctccaggct tttactcaag tttaattgtg     2340

catgagggtt ttattaaaac tatatatatc tccccttcct tctcctcaag tcacataata     2400

tcagcacttt gtgctggtca ttgttgggag cttttagatg agacatcttt ccaggggtag     2460

aagggttagt atggaattgg ttgtgattct ttttggggaa gggggttatt gttcctttgg     2520

cttaaagcca aatgctgctc atagaatgat ctttctctag tttcatttag aactgatttc     2580

cgtgagacaa tgacagaaac cctacctatc tgataagatt agcttgtctc agggtgggaa     2640

gtgggagggc agggcaaaga aaggattaga ccagaggatt taggatgcct ccttctaaga     2700

accagaagtt ctcattcccc attatgaact gagctataat atggagcttt cataaaaatg     2760

ggatgcattg aggacagaac tagtgatggg agtatgcgta gctttgattt ggatgattag     2820

gtctttaata gtgttgagtg gcacaacctt gtaaatgtga aagtacaact cgtatttatc     2880

tctgatgtgc tgctggctga actttgggtt catttggggt caaagccagt ttttctttta     2940

aaattgaatt cattctgatg cttggccccc atacccccaa ccttgtccag tggagcccaa     3000

cttctaaagg tcaatatatc atcctttggc atcccaacta acaataaaga gtaggctata     3060

agggaagatt gtcaatattt tgtggtaaga aaagctacag tcattttttc tttgcacttt     3120

ggatgctgaa atttttccca tggaacatag ccacatctag atagatgtga gctttttctt     3180

ctgttaaaat tattcttaat gtctgtaaaa acgattttct tctgtagaat gtttgacttc     3240

gtattgaccc ttatctgtaa aacacctatt tgggataata tttggaaaaa aagtaaatag     3300

ctttttcaaa atgaa                                                      3315


<210>  229
<211>  2911
<212>  DNA
<213>  homo sapiens

<400>  229
ggtgctcggc tcgcggggac tggcctcctt cggcagctgg aggcggtcac tcacgctggg       60

ctaggagctg aggcgagaag ggccatgcgg acggcgaggg agtccagagc cttgagcccg      120

gtgctcctcc ctcgcgcagc ggtggctctg cggccgctgg agtaaacact gcctttgttc      180

cctagcgcct cgtctttcgt cgccccgtgc cctcacgccg ccgggctctg gccggcccgc      240

cctcggtcct tgaaccccat ttcggctcgt gccgtgcgga tgcagctgcc gggcctgggt      300

ttgggcattg agcgggagga ggaggaggag cggcggcgcc tgggcggcat gcgatgggga      360

actgctgctg gacgcagtgc ttcggactgc ttcgcaagga agcggggcgg ctgcagcgag      420

taggcggcgg cggaggatcc aagtatttta gaacatgctc aagaggtgag cacttaacaa      480

tagagtttga gaatctagta gaaagtgatg aaggggagag cccaggaagc agtcataggc      540

ctcttactga ggaagaaatt gttgacctaa gagaaaggca ttatgattcc attgccgaaa      600

aacaaaaaga tcttgataag aaaattcaaa aagagttagc cttacaagaa gagaagttaa      660

gactagaaga agaagcttta tacgctgcac agcgtgaagc agccagggca gcaaagcagc      720

gaaagctctt ggagcaagaa aggcagagaa ttgtgcagca atatcatcct tccaacaatg      780

gagaatatca aagttcagga ccagaagatg acttcgaatc ttgtttgaga aatatgaagt      840

cacagtatga agtttttcga agtagtagac tctcatcaga tgctacagtt ttgacaccaa      900

atacagaaag cagttgtgat ttaatgacca aaactaaatc aactagtgga aatgacgaca      960

gcacatcctt agatctagag tgggaagatg aagaaggaat gaatagaatg cttccaatga     1020

gagaacgttc caaaacagag gaagacattc tacgggcagc acttaagtat agcaacaaga     1080

agactggaag taatcctaca tcagcctctg atgattccaa tgggctggag tgggaaaatg     1140

attttgttag tgccgaaatg gatgataatg gaaattccga gtattctgga tttgtaaatc     1200

ctgtattaga actgtctgat tctggcataa ggcattctga cacagatcaa cagactcgat     1260

agggtaaaat tgtgtgacct tgtttatcag ttatgaccaa atgttaaaaa ccaactagaa     1320

tgtataagtg attgtgctta gcctttttgt aagggagatg tgtaagaaac catgttgtaa     1380

atgcttattt tattacaaag gagtagggat gataggatct gaattgatac agaattaagt     1440

gcaatttcat catctgcctt ctgcttttca agaccaattt aatggtcctg tcatgttact     1500

gattaaattt actttgtctt gtctttatag catttctgtt tactatggta gatttccact     1560

ttcaattttt aaaattaatt ttactttgaa tgatttatga agcctatttc attgtctaac     1620

tatgaaaata ttaagacttt tttgttaatt ctcagccgat gtgaaggaag catgaggagg     1680

gatcgtcaga ttcagattta gaatagtgtt cccgtttcca gcattattta tttctatgac     1740

ttctttggat tttattatct aatagtaagt acagttgatg tgggtagatg actctaagaa     1800

atgctgaagt atcggcatta catgtgttta tttacatgtc ctagtatgat aatgttgatt     1860

caatctgaac aaaagataat ataaaaataa cccttcagag tttggacatt tcaagttggt     1920

aataataaaa aataatattt aagaagatat atatatatat atatttagtt ttttccactt     1980

cattttacat gccactatat tgactttaat tgatatacag tattaagttt ttaggtgcca     2040

ttatttttaa aaaattctat atttccaatg aacgatgtta gattttacac agaacatatt     2100

ctctgcatga tttcagaaaa gaaaatctaa aaaggtaata cgggtatttc aaataaaatc     2160

ctttctggta tgaaaggctc cattgatttt attaagcctt cctttacctt gtagtacaag     2220

gtgctttaat gggatagaac taagcatatc aatatctata actgcatttt gtgctagaca     2280

attactgttc ttttctctaa aatgtatatg tcaatttaca aggccaggga tagaaaacac     2340

tccataattg ctttccttga ttttgctgag gatttggtat gattttagta agcaaactgt     2400

tttttggttt ttccttaatg tttttaattt tttttcctct tgcaacaatg acggtgcatg     2460

ttcttataaa tataggaagg tccagatata aatagtaacc taaagttctt gctgtgctta     2520

aaaaaaaaaa tcatgtggcc ctttcaatat ttgaactgct aagcaatgac atctgtagtt     2580

ttatctcctt ttttatgtca tagaaattaa tatgatactt taaatatgta aatataatac     2640

attaggtaat gctattattt atatctgtct taacataatt taagttgtag ctgtgtcttg     2700

gaaatatttt taaggtaatc tatattcaca ttgcctgtgt taatgctttt taaagtttgt     2760

atacatcaga tgtatatttt tggtttggca taagctacga ttgtaatttt tcttggcttt     2820

ttgttcataa agaatttttt gaaggaatgg taacaaatgg taatttacaa atggttgtga     2880

ataaacacat ttttacactt aaaggtaaaa a                                    2911


<210>  230
<211>  3352
<212>  DNA
<213>  homo sapiens

<400>  230
tttaaagaga gaggatcgta ttatagatac cgcgggggca aagctaaaaa aggggggagg       60

ggggaggaaa aaattcaaga agcagaaacc cctcgcggag ttttactgga agaaaaaaac      120

gggtctgaaa gattcctcct cttcatcatc atcaaccatc attcattcac taccttgaca      180

ttccgggctt tgattgacag ctggagtggc aaaaagccat gaaacacgac agttcggtta      240

catgtgggct gctgacgggc cgctcgtaac cttcagttcg ggggcttgac aatttttttc      300

ttctttttct tctttttctt ttctttcttt ttttttccaa ctgaggggaa gagaagagaa      360

agagggggaa aggaggaccg aagaggagga ggaggggagg ggggaggagg aggaggtgga      420

ggaggaggag gaagatcagg aggaggagga agaagaggaa aaaagagaaa aagaagaaat      480

atcacagaaa aaaaaattct tcgttgtcta gactgggctt tttttccccc ctaaaaaata      540

gcatattgga gaattgggag aagtctcttt ggtttggaaa aaaaaaaaag gaatcttcag      600

cctagatcac tttcttatcc ggactgggat attaaatata cgacacatcc aggagtttat      660

tggagcgcag actgatggcg caaaggtacg atgagctgcc ccattacggc gggatggacg      720

gagtaggggt tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg      780

ttcaccacct gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc      840

cgcaccccaa tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg      900

acaaggacgc gatctatggg cacccgttgt ttcctctgtt agctctggtc tttgagaagt      960

gcgagctggc gacctgcact ccccgggaac ctggagtggc tggcggagac gtctgctcct     1020

ccgactcctt caacgaggac atcgcggtct tcgccaagca ggttcgcgcc gaaaagccac     1080

ttttttcctc aaatccagag ctggacaatt tgatgataca agcaatacaa gtactaaggt     1140

ttcatctttt ggagttagaa aaggtccacg aactgtgcga taacttctgc caccgataca     1200

ttagctgttt gaaggggaaa atgcccatcg acctcgtcat tgatgaaaga gacggcagct     1260

ccaagtcaga tcatgaagaa ctttcaggct cctccacaaa tctcgctgac cataaccctt     1320

cttcttggcg agaccacgat gatgcaacct caacccactc agcaggcacc ccagggccct     1380

ccagtggggg ccatgcttcc cagagcggag acaacagcag tgagcaaggg gatggtttag     1440

acaacagtgt agcttcacct ggtacaggtg acgatgatga tccggataag gacaaaaaac     1500

gccagaagaa aagaggcatt ttccccaaag tagcaacaaa tatcatgaga gcatggctct     1560

tccagcatct cacacatccg tacccttccg aagagcagaa gaaacagtta gcgcaagaca     1620

caggacttac aattctccaa gtaaacaact ggtttattaa tgccagaaga agaatagtac     1680

agcccatgat tgaccagtca aatcgagcag tgagccaagg agcagcatat agtccagagg     1740

gtcagcccat ggggagcttt gtgttggatg gtcagcaaca catggggatc cggcctgcag     1800

gacctatgag tggaatgggc atgaatatgg gcatggatgg gcaatggcac tacatgtaac     1860

cttcatcatg taaagcaatc gcaaagcaag ggggaagttt gcagagcatg ccaggggact     1920

acgtttctca gggtggtcct atgggaatga gtatggcaca gccaagttac actcctcccc     1980

agatgacccc acaccctact caattaagac atggaccccc aatgcattca tatttgccaa     2040

gccatcccca ccacccagcc atgatgatgc acggaggacc ccctacccac cctggaatga     2100

ctatgtcagc acagagcccc acaatgttaa attctgtaga tcccaatgtt ggcggacagg     2160

ttatggacat tcatgcccaa tagtataagg gaactcaagg gaaaaggaaa cacacgcaaa     2220

aactatttta agactttctg aactttgacc agatgttgac acttaatatg aaattccaga     2280

cagctgtgat tattttttac ttttgtcatt tttcatcaag caacagagga ccaatgcaac     2340

aagaacacaa atgtgaaatc atgggctgac tgagacaatt ctgtccatgt aaagatcctc     2400

tggaaaaaga ctccgagagt tataactact gtagtataaa tataggaact aagttaaact     2460

tgtacatttc tgttgatcac gccgttatgt tgcctcaaat agttttagaa gagaaaaaaa     2520

aatatatcct tgttttccac actatgtgtg ttgttcccaa aagaatgact gttttggttc     2580

atcagtgaat tcaccatcca ggagagactg tggtatatat tttaaacctg ttgggccaat     2640

gagaaaagaa ccacactgga gatcatgatg aacttttggc tgaacctcat cactcgaact     2700

ccagcttcaa gaatgtgttt tcatgcccgg cctttgttcc tccataaatg tgtcctttag     2760

tttcaaacag atctttatag ttcgtgcttc ataagccaat tcttattatt atttttgggg     2820

gactcttctt caaagagctt gccaatgaag atttaaagac agagcaggag cttcttccag     2880

gagttctgag ccttggttgt ggacaaaaca atcttaagtt gggcagcttt cctcaacaca     2940

aaaaaaagtt attaatggtc attgaaccat aactaggact ttatcagaaa ctcaaagctt     3000

gggggataaa aaggagcaag agaatactgt aacaaacttc gtacagagtt cggtctatta     3060

attgtttcat gttagatatt ctatgtgttt acctcaattg aaaaaaaaaa gaatgttttt     3120

gctagtatca gatctgctgt ggaattggta ttgtatgtcc atgaattctt cttttctcag     3180

cacgtgttcc tcactagaag aaaatgctgt tacctttaag ctttgtcaaa tttacattaa     3240

aatacttgta tgaggactgt gacgttatgt taaaaaaaaa aaggtgttaa gtcacaaaaa     3300

gcggtaataa atatttcatt tttgattttt tgttaaaaaa aaaaaaaaaa aa             3352


<210>  231
<211>  2717
<212>  DNA
<213>  homo sapiens

<400>  231
gcgcttccgg tgcgacgctg tctctccatg ccaggactga gttgtggggg agggaggcgg       60

ttagcgggct ttagcgcctt ttctggcggc ggtagatttg aagcgcttca aaggaccgga      120

cccagagaag aggaaaactc taccggtgca ggagcacagg gatcagttgt ccttgttttt      180

ttttggtctt ttcttcattt gaagattaag tattggagcc atgggaataa aggttcaacg      240

tcctcgatgt ttttttgaca ttgccattaa caatcaacct gctggaagag ttgtctttga      300

attattttct gatgtgtgcc ccaaaacatg cgagaacttt cgttgtcttt gtacaggtga      360

aaaggggacc gggaaatcaa ctcagaaacc attacattat aagagttgtc tctttcacag      420

agttgtcaag gattttatgg ttcaaggtgg tgacttcagt gaaggaaatg gacgaggagg      480

ggaatctatc tatggaggat tttttgaaga cgagagtttc gctgttaaac acaacaaaga      540

atttctcttg tcaatggcca acagagggaa ggatacaaat ggttcacagt tcttcataac      600

aacgaaacca actcctcatt tagatgggca tcatgttgtt tttggacaag taatctctgg      660

tcaagaagtt gtaagagaga ttgaaaacca gaaaacagat gcagctagca aaccgtttgc      720

ggaggtacgg atactcagtt gtggagagct gattcccaaa tctaaagtta agaaagaaga      780

aaagaaaagg cataaatcat catcatcttc ctcctcctca tctagtgact cagatagctc      840

aagtgattct cagtcctctt ctgattcctc tgattccgaa agtgctactg aagagaaatc      900

aaagaaaaga aaaaagaaac atcggaaaaa ttcccgaaaa cacaagaaag aaaagaaaaa      960

gcgaaagaaa agcaagaaga gtgcatctag tgagagtgaa gctgaaaatc ttgaagcaca     1020

accccagtct actgtccgtc cagaagagat ccctcctata cctgaaaata gattcctaat     1080

gagaaaaagt cctcctaaag ctgatgagaa ggaaaggaaa aacagagaga gagaaaggga     1140

aagagagtgt aatccaccta actcccagcc tgcttcatac cagagacgac ttttagttac     1200

tagatctggc aggaaaatta aaggaagagg accaaggcgt tatcgaactc cttccagatc     1260

cagatcaagg gatcgtttca gacgtagtga gactcctcca cattggaggc aagagatgca     1320

gagagctcaa agaatgaggg tatcaagtgg tgaaagatgg atcaaggggg ataagagtga     1380

gttgaatgaa ataaaagaaa atcagagaag tccagttaga gtaaaagaga gaaaaataac     1440

agatcacagg aatgtatctg agagtccaaa cagaaaaaat gaaaaggaga agaaagttaa     1500

agaccataaa tctaacagca aagagagaga catcagaaga aattcagaaa aagatgacaa     1560

gtataaaaac aaagtgaaga aaagggccaa atctaaaagt aggagtaaga gcaaagagaa     1620

atcaaagagt aaagaaagag attcaaaaca taatagaaat gaagaaaaga ggatgaggtc     1680

aaggagtaaa ggaagggatc atgaaaatgt taaagaaaaa gaaaagcagt ctgattctaa     1740

aggaaaagat caggaaagga gtagaagtaa agagaagtct aaacagttag aatcaaagag     1800

taatgagcat gatcacagta aaagtaagga aaaggataga cgcgcacaat ccaggagtag     1860

agaatgtgat ataactaaag gtaaacacag ttataatagc agaacaagag aacgaagcag     1920

aagtagggac agaagcagaa gagtgcgatc aagaacccat gacagagatc gcagcagaag     1980

caaggagtac catagataca gagaacagga atacaggaga agaggacggt cacgaagccg     2040

agagagaaga acaccaccag gaagatcaag aagtaaagat aggaggagaa ggaggagaga     2100

ctcacggagc tcagagagag aagaaagtca aagcagaaac aaagacaaat acagaaacca     2160

agagagtaag agctcacaca gaaaagaaaa ttctgagagt gagaaaagaa tgtactctaa     2220

aagtcgtgat cataatagct caaataacag cagggaaaaa aaggctgata gagatcaaag     2280

tcccttctca aaaataaaac aaagcagtca ggacaatgaa ttaaagtcct ccatgttgaa     2340

aaataaggag gatgagaaga tcagatcctc agtggaaaaa gaaaaccaaa aatcaaaagg     2400

tcaagaaaat gaccatgtac atgaaaaaaa taaaaaattt gatcatgaat caagccctgg     2460

aacagatgaa gacaaaagcg gatgagtgag ttatataaac ttacttccat tctgtttcgg     2520

attttaagtt tgagagactt gctaatgaat ctcctttatg ttgttttcct tttcattgtt     2580

tttggattgt tttatgtttg tccttttttt tcttaatgtg gatttcattg agttgatttt     2640

ttgataatct gcaatctgga taatttgtac tgctaaagtt ttaataaact cgacatgaga     2700

aaaacaaaaa aaaaaaa                                                    2717


<210>  232
<211>  1259
<212>  DNA
<213>  homo sapiens

<400>  232
ctggactctg agtgtggagc caggggcagc agggctgtct ctgaactccc aggcttgtgt       60

ttgagcaaag gaattctctc cccctccctc tcccctcggg gcgggcccga gcctccagct      120

ataaactccc cggagcttca gtgccctcag caaggctcag cctcaagatt cacagcatct      180

cagacacagc ctaggccgca ccaggatgtc ggacaccgag gagcaggaat atgaggagga      240

gcagccggaa gaggaggctg cggaggagga ggaggaagcc cccgaagagc cggagccggt      300

ggcagagcca gaagaggaac gccccaaacc aagccgcccc gtggtgcctc ctttgatccc      360

gccaaagatc ccagaagggg agcgcgttga cttcgatgac atccaccgca agcgcatgga      420

gaaagacctg ctggagctgc agacactcat cgatgtacat ttcgagcagc ggaagaagga      480

ggaagaggag ctggttgcct tgaaggagcg cattgagcgg cgccggtcag agagagccga      540

gcaacagcgc ttcagaactg agaaggaacg cgaacgtcag gctaagctgg cggaggagaa      600

gatgaggaag gaagaggaag aggccaagaa gcgggcagag gatgatgcca agaaaaagaa      660

ggtgctgtcc aacatggggg cccattttgg cggctacctg gtcaaggcag aacagaagcg      720

tggtaagcgg cagacggggc gggagatgaa ggtgcgcatc ctctccgagc gtaagaagcc      780

tctggacatt gactacatgg gggaggaaca gctccgggcc cggtctgcct ggctgcctcc      840

atcacagccc tcctgccctg ccagggagaa agcccaggag ctgtcggact ggatccacca      900

gctggagtct gagaagttcg acctgatggc gaagctgaaa cagcagaaat atgagatcaa      960

cgtgctgtac aaccgcatca gccacgccca gaagttccgg aagggggcag ggaagggccg     1020

cgttggaggc cgctggaagt gaggatgccg ccccggacag tggcacctgg gaagcctggg     1080

agtgtttgtc ccatcggtag cttgaaataa acgctcccct cagacacccg ctgggttctc     1140

tgatgttatt atggttgaga tgcagctggt ctctcctggt taattgactt cttattacca     1200

acaagttact tgaaagagtg tcaccaataa tcattaaagt acggcaggct gaaccttca      1259


<210>  233
<211>  2995
<212>  DNA
<213>  homo sapiens

<400>  233
ggtgactctc ggagcgggag gcggaggctg aggcggccgc tcctgctgct gctactgccg       60

ccgccgcagc ggctgctcgg gctgagcacg ccccggaaca ggccgccgcg cgctgcgcgc      120

cggacccgct gcccctgccg gcccggccgg gtcgggcggc ccagggaccg acagacttga      180

caacggtgac agcactgggg cggcaccttc ctacttctgc ccagccacag ccctcccctc      240

acagttgagc acctgtttgc ctgaagttaa tttccagaag caggagtccc cagagccagg      300

cagggggatg aaccgcgagg gagctcccgg gaagagtccg gaggagatgt acattcagca      360

gaaggtccga gtgctgctca tgctgcggaa gatgggatca aacctgacag ccagcgagga      420

ggagttcctg cgcacctatg caggggtggt caacagccag ctcagccagc tgcctccgca      480

ctccatcgac cagggtgcag aggacgtggt gatggcgttt tccaggtcgg agacggaaga      540

ccggaggcag tagctgcaaa gcccttggaa caccctggat gctgttgagg gccaagagat      600

ctgtgtggct cctgggccgg ctgagtggca gcagcccccc ttgccccacc tcccccttcc      660

cctacccaac cctgccctgc cccaccccac ctcacagcta ctcagtgggg ctggcatcaa      720

gggagacacc agtggtgcgt ttataattgg cttaaaggga tggacttgtg attggctgca      780

ggaagaaact tttttatttt ttaaatcttg accaacagaa accttttatt tttatttctg      840

actcttattt tttaaaaaat ttgcgcctcg gtatctggct tccctggaag ctctccgagc      900

tctggtgctt tagttaggtc atttttttag aaatgtgaag aggtctgatt ggctgcttaa      960

actggaaagg atctgtgatt ggctggttaa tgggaaacgg tttttttctt tggctgcagg     1020

tgttctgctg atatcaacag cttccctatt ttgaatgcag aaaacagggt ctgggacatt     1080

agtcgttata tttgacttga aaagaaagaa accaagtgcg ctttgcaata tttattacac     1140

aaagaacttg ctgctgcctt cacatttggg gtttgtgttt gattggcttt cgatgcgtgt     1200

gtttggtttc ccattggttc acctgtgact cctgttgcca tggattcacc cccctctgct     1260

gccggctctg ggcctgaggg tccacctgga gagtacattt gctttaatga gtgcacctgc     1320

ctccaccagc aaggggaccc cgagaaccct gagcagggtc cacagctgga aagttgggcc     1380

cctgaggagc tttgtgtcgt cttgaacgag cagcccaggg cctagaggta accgttaggc     1440

gggatttatg tgcactgcct gcatgagctg gcaaccagcc agcgtccctt ggtgagaaag     1500

ggattgctga ggcaccgtcc aggccccacc ggccaggccg cgcccagcag aggcgtacta     1560

cccagctctg tcctcttggc catccttctg tgtaccactt cctgaggcct cattttgggg     1620

gtcatcttgg aaaggggagg agcttctccc agtgtgagac cccaaagact ctggaggtca     1680

tctggcggag gtctctggga gcccagaacc cacataaaag ccccagcttg gctcacaagg     1740

cccaggagac ctccagctaa acaccaaccc ctgacctacc ccagccaggc tcctacctgt     1800

ctgctgccag cacagtaggt cccggccagc tctggagttc tctcatcgga ggcccatgcc     1860

ctccactcca ctgcctttgg aagggtctct ctccaggtca gcctggaagg gacagtatcg     1920

tttgtttatg aaatgccact gggacagctg gctgggcctt caccaagcaa gtcccttcag     1980

actggccctt aagccaaact caggcccaga attgcagttc agaatggcag tcctggaggc     2040

agggggtgag gggcaggtct agtgttcctg caccaaacct aagtccttcc acctgccacc     2100

cccttccctg ggagggaggt ggtcctccta tctccctggc tcactggcag gtgtgggatc     2160

tggggagagc ggctggagaa agatgcagtc ctcaggaagg gggccgccac cctcccctat     2220

gctggtagat gctgaggccc ctaggtgccc agggccagtg ggaccctctc agaaccaaat     2280

ctttcccctt tctcggggct tggggctcgg gccgtagggg ctcctgagtg tcatgaagtg     2340

cacaggagcc aaatgaccga gccctggaga gccccatggt gggtaggtgg ttcgtgctgt     2400

gctctggcac catcagcctg ttccagaagg aggattcgag catcaggcta agaccctgtg     2460

tcctccacca tgcactcacc cctagccctg gttagctgac agtcagctgt ggggaacaca     2520

gctacaaccc taccctggca gggacctgag agcatctcag gaggggcagc gcatgtgtgc     2580

atgtgctgtg tgagtgagca cacccgtgtg cacactcata cacatgtgca cacacacgca     2640

ctctccccgc tcaggggcct ggaggtctgg ctgagcccct ggggaaaggt gagttctttc     2700

atctccctcc tccaggtcgg agtgcctgga gtcaggtgtc gaggccacat tgctggctgc     2760

cccctctttg tagctcctat aaagggccca cacctggtgg atacctggtt gagtgtgtgg     2820

tctctgcccc agcctgtcct tgtcacgatc acaggccttg cttttgtaac aatgatgacc     2880

ccggcctgtc tcatcttctg aagaggaaaa gtcaaagtgt tgctgtggct ccatatttca     2940

actaaaaata tatctgttgg agaaagaaat taacaataaa gaattttcat aggtt          2995


<210>  234
<211>  7431
<212>  DNA
<213>  homo sapiens

<400>  234
cgcgcgcccg ggggagcgca gagtttggaa agtcttcgag aagcttcaga ggagggaagg       60

gggtgggaag agtgggggtg caagagagaa aaacccgcct cttgcgagtt gagcgaggaa      120

gagggggggg aaggctccga gttccgcttc ctgaacggcg ggtggataga gaaggttggc      180

gcggggaaga ccggcgggag gcgcgccccg ggcccgcggc gcgattggcg tgaccggcga      240

tggccggtga gcggacccgc aggttcaccc ggagcctgtt gagacctggg caggcggccg      300

agctccggca cagcgccgcg tccgccgccg cggtggcagt cagcagccgg cagcagcagc      360

ggcaagaaaa gcctaggctt ctcgagcctt tggattatga gactgtcatt gaagaacttg      420

aaaagaccta ccggaatgat cctcttcaag atctcttgtt cttccccagt gatgactttt      480

cagcagccac agtttcctgg gatatccgca cgttgtactc aacagtacct gaagatgcag      540

agcacaaggc agaaaattta ctggttaagg aggcttgtaa attttatagt tcccagtggc      600

atgtggtaaa ctacaaatat gaacaatatt ctggagacat tcgacagcta ccccgagcag      660

aatacaaacc agagaagctt ccttcacatt cctttgagat tgaccatgaa gatgctgata      720

aggatgaaga taccacttcc cactcgtctt ccaagggggg tggaggagcg ggaggaactg      780

gtgttttcaa gtccggctgg ctctacaagg ggaattttaa cagcaccgtg aacaacaccg      840

ttactgttcg gtcattcaaa aagcgctact tccagctgac tcagttacca gataactcct      900

acattatgaa cttttacaaa gatgagaaaa tatccaaaga acccaaagga tgcatctttt      960

tggattcctg tacaggagtg gtgcagaata acagactaag aaaatatgcc tttgaattga     1020

aaatgaatga tctgacctat tttgtgctgg cagctgaaac agagtcagat atggatgaat     1080

ggatccacac cctcaaccgc attctgcaaa tcagtcctga ggggcccctc caagggagga     1140

ggagcacaga gctcactgat ctgggtctgg attcgctgga taattctgta acttgtgaat     1200

gcacgccaga ggaaacagat tcttcagaga acaacctaca cgcagacttt gcaaagtacc     1260

tcacagaaac agaagatact gtaaaaacaa ctcgaaacat ggagaggcta aatctgttct     1320

ctctagatcc agacatagat accttgaaac ttcaaaaaaa agatctcttg gaacctgagt     1380

ctgtgatcaa accatttgaa gaaaaagctg ccaagagaat catgatcatc tgtaaagccc     1440

tcaactcaaa tcttcaggga tgtgttacgg agaatgaaaa tgatccgata acgaatattg     1500

agcctttttt tgtgagtgtg gcactttatg acctcagaga cagcaggaag atttctgctg     1560

attttcatgt ggatctaaac catgctgctg tcagacagat gctcttgggg gcttctgtgg     1620

ctttggaaaa tggcaacatc gacaccatca ctccaagaca atcagaagaa cctcacatca     1680

agggacttcc agaggaatgg ctaaaatttc caaagcaggc tgtattttct gtaagcaatc     1740

cacattctga aattgttttg gtggccaaaa tcgaaaaagt cttgatggga aacattgcaa     1800

gtggtgccga accttatatt aagaacccag actccaacaa gtatgcacaa aagatactaa     1860

aatccaacag acaattctgc agcaaattgg gaaaataccg tatgcctttt gcttgggcag     1920

taagatcagt atttaaggac aaccagggaa atgtggacag agactcaaga ttttcaccat     1980

tgtttagaca agaaagtagc aagatttcaa ctgaggacct agttaaacta gtatcagatt     2040

atagaagggc cgacagaata agcaaaatgc agaccattcc tggaagcctg gatattgctg     2100

ttgacaacgt tcccttggag catccaaatt gtgtaacatc gtcctttatc cctgtcaagc     2160

ctttcaacat gatggctcaa acagaaccca cagtggaggt ggaagaattt gtttacgatt     2220

caacaaagta ttgtcggcct tacagagtat ataaaaatca aatttatatt taccccaaac     2280

acctcaagta tgatagccag aaatgcttca acaaggcacg gaatataact gtgtgcattg     2340

aattcaaaaa ttcagatgaa gaaagtgcca agcccctgaa gtgtatttat ggaaaacctg     2400

gagggcccct cttcacctca gccgcctaca cagcagttct gcaccactct cagaatccgg     2460

atttctcaga tgaggtgaaa attgagctac caacacaact ccatgagaaa caccatattt     2520

tgttttcttt ttatcacgtc acctgtgaca tcaatgcaaa agctaatgcc aaaaagaagg     2580

aggctctgga aacgtcagtt ggatatgctt ggcttcctct gatgaaacac gatcagatag     2640

cttctcaaga gtacaacatc ccaatagcaa caagtctgcc tcctaattat ttaagctttc     2700

aagattctgc aagtggaaag catggtggga gtgacattaa atgggttgat ggtggcaaac     2760

cacttttcaa agtgtcgaca tttgttgtat caacagtaaa tactcaggat ccacatgtga     2820

atgcattttt ccaagagtgc caaaaaagag agaaagatat gtctcagtca cctacctcaa     2880

atttcatccg ctcttgtaag aacttattga atgtggaaaa gattcatgca atcatgagtt     2940

ttctgcctat aattttgaat cagctcttca aagttctggt acagaatgag gaagatgaaa     3000

taactacaac tgtcaccagg gttctgaccg acattgtggc caagtgccat gaggagcagc     3060

tggatcattc tgtccagtca tatattaagt tcgtgttcaa gaccagggca tgcaaggaga     3120

ggactgtaca tgaggaactg gctaaaaatg tgactggtct tttgaaatca aatgactcaa     3180

caacagtaaa gcatgtccta aagcattcct ggttcttctt tgcaattatc ctaaaatcga     3240

tggcacagca cttgattgac acaaataaaa tccagcttcc ccggcctcag agatttcctg     3300

aatcttacca aaatgaattg gacaatcttg tcatggtcct atccgaccat gtgatttgga     3360

aatacaagga tgcacttgaa gaaacaagaa gggcaaacca cagcgttgcc agatttctca     3420

agcgctgctt tacatttatg gaccgagggt atgtgtttaa gatggtcaac aattacatca     3480

gcatgttctc ctccggtgac cttaagacct tgtgccagta taaatttgat tttcttcaag     3540

aagtatgtca acatgaacac tttatccctt tgtgtctgcc cataagatca gcaaacattc     3600

cagatccttt gacaccttca gaatcgactc aagagttaca tgcatcagat atgcctgaat     3660

attcagtcac aaatgaattt tgtcgcaaac acttcttaat cggaattctg ctccgagaag     3720

ttggctttgc cctgcaggaa gaccaagatg tcagacactt agctttagct gtcctaaaaa     3780

atctaatggc taagcattca tttgatgatc gatacagaga gccaagaaag caggcccaga     3840

tagcaagttt atacatgccc ctgtacggca tgctcctgga caatatgcca aggatttatc     3900

tgaaggacct gtatcctttt actgtcaata catctaatca ggggtctaga gatgatctaa     3960

gcaccaatgg aggatttcaa agccagacag ctatcaaaca tgcaaactct gtggatacat     4020

cattttctaa agatgtttta aattccatag cagcattttc atcaatagct atttctacag     4080

taaaccatgc tgactccaga gcatctttag caagtcttga ctccaatcca agtaccaatg     4140

agaagagcag tgagaagacg gacaactgtg aaaagatccc aagacccttg tctttgattg     4200

gctcaactct tcgatttgac aagttagatc aagcagaaac caggagtctc ctgatgtgtt     4260

ttcttcacat tatgaaaacg atttcgtacg agactctgat tgcctactgg cagagagctc     4320

ccagcccaga ggtgtccgac ttcttcagca tcttggacgt ttgtcttcaa aatttcagat     4380

acctaggaaa acgcaacata ataagaaaaa ttgctgctgc atttaaattt gtgcagtcca     4440

cccagaacaa tggaactctc aaaggatcca atccttcctg ccagacatca ggtctcttgt     4500

cacaatggat gcactccact tccagtcatg aaggccataa gcagcacaga tcacaaactt     4560

tacctataat tcgaggcaaa aatgcacttt ctaaccccaa actcttacag atgttagaca     4620

ataccatgac cagcaactcc aatgaaatag acatcgtgca tcatgtagac actgaggcca     4680

atatagctac ggaggtttgc ctcactattc tggacctgtt atccctcttc acacagactc     4740

atcagagaca actccaacaa tgtgactgtc aaaattcatt gatgaaaagg gtctttgata     4800

cctacatgct ctttttccaa gtcaatcagt cagccacagc gctgaagcat gtgtttgcct     4860

ccttgagact gtttgtatgc aagtttcctt cagcgttctt tcaagggcct gctgacctct     4920

gtggatcatt ctgttacgaa gtcctaaaat gctgtaacca caggtcacgg tcaactcaga     4980

cagaagcctc agcccttctg tactttttca tgaggaagaa ttttgaattt aacaagcaga     5040

agtcaattgt ccggtcccac ttacaactca tcaaagctgt gagccagtta atagccgatg     5100

ctgggattgg aggctctcgg tttcaacatt cgcttgcaat taccaataat ttcgccaatg     5160

gagataagca aatgaaaaac agcaatttcc cagcagaggt gaaggacctg actaagcgta     5220

taaggactgt tttgatggcc acagctcaga tgaaggagca cgagaaggac cccgagatgc     5280

tggtggatct ccagtacagc ctggcaaact cctacgcaag cactcctgaa ctacgcagga     5340

cctggctgga aagtatggcc aagattcatg ccagaaacgg agatttatct gaggctgcca     5400

tgtgttacat ccatattgct gctctcattg cagagtatct gaaaagaaag ggttactgga     5460

aagtggaaaa gatttgcaca gcatccctgc tctcggagga tacccacccc tgtgatagca     5520

actcattact aacaactccc agtggaggaa gcatgttctc tatgggatgg ccagcttttt     5580

tgagcattac accaaacatt aaggaagaag gagcgatgaa agaggattct ggaatgcaag     5640

atacaccata caatgagaat atcctggtgg agcagctata catgtgtgtg gagtttctct     5700

ggaagtctga gcgatatgaa ctcattgctg atgtcaacaa gcccatcatt gctgtctttg     5760

agaaacaacg agacttcaaa aaattgtcag atctctacta cgacattcat cggtcatatc     5820

tgaaagtggc agaggtggtg aattcggaga agcggctgtt tggtcgctac tatcgtgtgg     5880

cattttatgg gcagggcttt tttgaagaag aagaaggtaa agagtatatt tataaagagc     5940

ctaagctgac aggtctgtcc gagatttccc aaagattact caagctctat gcagataaat     6000

ttggagcaga caatgtgaag ataatccagg attccaacaa ggtaaacccc aaggatttgg     6060

accccaaata tgcctacatc caggtgacct atgtgacgcc gttctttgag gaaaaggaaa     6120

tcgaagaccg gaagacagat ttcgaaatgc accacaacat caaccgcttt gtcttcgaga     6180

cacccttcac gctgtcgggc aagaagcacg gtggggtggc ggagcagtgc aagcggcgga     6240

cgatcctgac aacgagtcac ctgttcccct acgtgaagaa gagaatacaa gtaattagcc     6300

aatcgagcac agaactgaat ccaattgaag tggcaattga cgagatgtcc aagaaggttt     6360

ctgagcttaa tcagctttgc acaatggaag aagtggacat gatcagactg cagctcaaac     6420

tgcaaggaag tgtcagcgtg aaggttaatg ctgggccaat ggcctatgca cgagcttttc     6480

ttgaagaaac caatgcaaag aagtaccctg acaaccaagt aaagcttttg aaggagatct     6540

tcaggcaatt tgcagatgca tgtgggcagg cccttgacgt gaatgagcgc ctcatcaaag     6600

aggaccagct ggagtaccag gaagaactga ggtcccacta caaggacatg ctcagcgaac     6660

tctccacagt catgaatgag cagattacgg gcagggacga cctgtcaaag cgcggagtgg     6720

accaaacctg cactcgagta attagcaaag caactccggc cctacccacg gtctccatct     6780

catctagtgc tgaagtctga gggctctgca gcatcagacc cacctctaag agaactttct     6840

gaatttgcag ctaatctcgg ggaagagaaa gataggttta atttatttga agttttcatg     6900

gtgttaatat ttttgtttac ctcgctagct tcagaatttt gccaacctct gaatttgcac     6960

attttgtata attttttttt ctttgagcag tgttgatcaa gccaggttga atatttgcca     7020

tgaaattcca gtgaatgtgt agctcaaatg caaaccctaa gtttgctgtc agttattgta     7080

tggtcagtac cccagtccta gtacacatat tttaaaggtt aaagtgaatg tttttgtaac     7140

atttaagcat atttcagatg taaataaaag attgtaaaat atacggtttt taccaaattt     7200

aaaagatcct ttttagttaa tactatgaca gtactaaaaa tatatgaata acatttcaga     7260

taccattata ttaaaatatt tgtgtatgtg tacaaaagcg ttgataaata ctaatcttta     7320

aagtttgtgg agttccttta tttgtaatat atgtgctctt aaaagcaatg ggatgtgaaa     7380

ttatgaaagt attttattgt tcatagaaat aaaaaacaca gttactttgc a              7431


<210>  235
<211>  6638
<212>  DNA
<213>  homo sapiens

<400>  235
gcagtgagtc cacccgcccg ccgaggtccg cccgcccgcc gagacccgcc cgccgccgct       60

gccatggccg aagtgcgcaa attcaccaaa cggctcagca agcctggcac ggcggctgag      120

ctccggcaga gcgtgtctga ggccgtgcgg ggctccgtgg tgctggaaaa ggccaaagtt      180

gttgagcccc tggactatga gaatgttatt gcccaaagaa aaacccagat ttacagcgac      240

cccctccgag atctgcttat gttcccaatg gaagatatat ctatctcggt gataggtcgt      300

caacgcagaa cggtgcagtc tactgtacca gaagatgctg aaaagagggc ccagagttta      360

tttgttaaag agtgtattaa aacctatagc acagattggc acgtggtaaa ctacaagtat      420

gaggacttct ctggggactt tcgaatgttg ccatgtaaat ctttgagacc agaaaagatt      480

cctaatcatg tatttgagat agatgaagac tgtgagaaag atgaggactc atcttcttta      540

tgttctcaga agggtggtgt gataaaacaa ggctggttgc ataaagcaaa tgtaaatagt      600

accatcacag taaccatgaa ggtattcaag agacgatatt tttacttgac ccaacttcct      660

gacggttcat atattctcaa ttcctataaa gatgagaaaa attcaaaaga atcgaaaggt      720

tgcatctact tggacgcctg cattgatgtt gttcagtgcc ccaaaatgcg ccgtcatgct      780

tttgaactca agatgttaga taaatatagc cattatctgg ctgctgaaac tgagcaggaa      840

atggaggaat ggttgataac tttgaaaaag attattcaga tcaacaccga cagtttagtt      900

caagaaaaaa aggagacggt agaaacagca caagatgatg aaactagcag ccaaggaaaa      960

gccgagaaca tcatggcaag tttggaaagg agcatgcatc cggaactgat gaagtatgga     1020

agagaaactg aacaactaaa caaactcagt agaggagatg gaagacagaa tctcttttct     1080

tttgattcag aagttcagag gttggacttt tcaggaattg aacctgatat aaagccattt     1140

gaagaaaaat gcaataaacg tttcctggtg aattgccatg atttaacttt caatatcttg     1200

ggccaaattg gagacaatgc aaaaggacca cccacaaatg ttgagccctt ttttatcaat     1260

cttgccttat ttgatgtaaa gaacaattgt aagatttcag cagactttca tgtagacctg     1320

aatcccccat ctgtccgtga aatgctgtgg ggctcttcaa cccaactggc cagtgacggt     1380

agcccaaagg gctcttcacc cgaatcttac attcatggaa ttgccgaatc tcagttacgc     1440

tacatacaac agggaatttt ctcagtgacg aatccacatc ctgaaatttt tctagttgcc     1500

agaattgaaa aggtactaca gggaaacatt acacactgtg cagaacccta tatcaaaaat     1560

tctgatccag taaagacggc ccagaaggtg cacaggacag ctaaacaagt gtgtagccgc     1620

cttggacaat acagaatgcc cttcgcttgg gctgccagac ccattttcaa agatactcaa     1680

ggctctcttg atctggatgg gagattttct cctctgtata aacaagacag tagcaagctt     1740

tcaagtgaag acattctcaa gttgctctca gaatataaga agccagaaaa gaccaaactg     1800

cagattattc ctgggcagct aaacatcaca gtagaatgtg ttcctgtgga tttatcaaat     1860

tgtattactt cttcatatgt gcccttgaag ccttttgaaa agaattgcca aaatattact     1920

gtggaggttg aagagtttgt tccagaaatg acaaaatatt gttatccatt tactatttac     1980

aaaaaccatc tgtatgtata tcccctgcaa ttaaaatacg atagccagaa aacatttgcc     2040

aaggcaagga acattgcagt ctgtgtggaa ttccgggatt cagatgaaag tgacgctagt     2100

gccctaaagt gtatttatgg aaaacctgca gggtctgttt ttaccacaaa tgcttatgct     2160

gttgtctcgc atcacaacca aaatccagag ttctatgatg agattaaaat tgagcttccc     2220

attcacctac atcaaaaaca tcatttgctt ttcacttttt atcatgtaag ttgtgaaatt     2280

aacacaaagg gaacaaccaa aaagcaagac acagttgaaa ctccagttgg gtttgcctgg     2340

gtacctttgc tgaaagatgg tagaatcatc acatttgagc agcagctgcc agtttccgcc     2400

aatcttcccc caggctactt gaatctgaat gatgcagaat caagaaggca atgtaacgtg     2460

gatattaaat gggtagatgg tgcaaagcct ttgttgaaga ttaaaagcca cttagaatct     2520

accatttaca ctcaagatct gcatgtgcac aaattcttcc atcattgcca gctgattcag     2580

tcaggctcga aagaagttcc aggggagctc attaaatatt taaagtgttt gcatgccatg     2640

gagatccaag tcatgataca gtttctacct gtaattctta tgcaactctt ccgagttctc     2700

acaaatatga cccatgaaga tgacgttcct atcaactgca ccatggttct cttacatatt     2760

gtatcaaagt gccatgaaga aggcttggat agttatctaa gatcattcat aaagtatagc     2820

ttccgacctg aaaaaccgag tgctcctcag gcccagctga tacatgaaac cctggctact     2880

acgatgatag caatattgaa acagtctgca gattttttat caataaacaa attgctaaag     2940

tactcatggt ttttctttga aataattgca aagtcaatgg ccacatactt gttggaagag     3000

aataagatta agcttccccg aggccagaga tttcccgaga catatcatca tgtcttacat     3060

tcactgcttc ttgcaataat tccccatgtg actattcggt atgcggagat tcccgatgag     3120

tccagaaatg tgaactatag tttggctagc ttcctgaagc gctgtttgac actaatggat     3180

agaggattta ttttcaattt aataaatgac tatatatctg gattcagccc caaagatcct     3240

aaggttctgg ctgaatacaa gtttgaattt ctgcaaacaa tttgcaatca cgaacattac     3300

attcctctga acttgccaat ggcatttgca aaacctaaac tgcagcgggt tcaagattca     3360

aatcttgaat acagtttatc agatgagtat tgcaagcatc acttcttggt tggtctactt     3420

ctgagggaaa cttccattgc tcttcaggac aattatgaga tcagatatac agctatctct     3480

gttataaaga atcttttgat aaaacatgca tttgacacaa gataccagca caagaaccaa     3540

caagccaaaa tagcacaatt gtacctcccc tttgttggac tacttttgga aaatatacag     3600

cgattagcag gtcgagatac cttgtattct tgtgcagcca tgcctaattc tgcatccaga     3660

gatgagtttc catgtggctt tacttcacct gccaatagag ggagtctgag cactgacaaa     3720

gacaccgctt atgggtcttt tcaaaatgga catggaatta agagagaaga ttcaagaggt     3780

tccctcatcc cagaaggagc aacaggattt ccagatcagg gcaacactgg tgaaaatacc     3840

cgacagagtt ctacaaggag tagtgtatcc cagtataacc gcctggatca gtatgaaatc     3900

agaagcctcc tgatgtgcta cctgtatata gtaaaaatga tttcagaaga tactctctta     3960

acttactgga ataaagtatc acctcaggag ctcataaaca ttcttatact tttagaagta     4020

tgcttgtttc actttagata tatggggaaa agaaacatag caagggtgca tgatgcctgg     4080

ctgtcaaaac acttcggaat agaccgaaaa tcgcaaacca tgcctgctct tcgaaacaga     4140

tcaggagtaa tgcaggcccg gcttcagcat cttagtagcc tagaaagttc atttacactt     4200

aatcacagtt ctacaacaac tgaagcagac attttccacc aggcacttct tgaaggcaat     4260

acagctactg aagtttccct aacagtacta gacaccatat catttttcac tcagtgcttc     4320

aagacccaac ttttaaataa tgatggccat aacccattaa tgaaaaaagt gtttgatata     4380

catcttgctt ttcttaaaaa tggacaatct gaagtgtcgc tgaaacatgt atttgcctca     4440

ctgagagctt tcatcagtaa gtttccttca gcatttttca aaggaagagt aaacatgtgt     4500

gctgcatttt gctatgaggt tttaaagtgc tgcacatcga agattagctc aaccaggaat     4560

gaagcatctg cacttttgta tcttttgatg agaaacaact ttgagtatac caaaaggaaa     4620

acctttttga ggacacatct acagataata attgctgtaa gccaactgat agctgatgta     4680

gcactaagcg gaggatcaag atttcaggag tctttattca ttatcaataa ttttgcaaat     4740

agtgacagac ctatgaaggc aactgccttt cccgcagaag tcaaagactt gaccaagaga     4800

atccgcactg ttcttatggc cactgcccaa atgaaggagc atgagaaaga ccctgaaatg     4860

ctaattgatc tccagtatag cttagccaag tcctatgcaa gcaccccaga gctcaggaaa     4920

acctggcttg atagcatggc caagattcat gtaaaaaatg gagatttttc agaggctgcg     4980

atgtgttatg tccatgtagc agctctagtt gcagagtttc ttcatcgaaa aaaattattt     5040

cctaacggat gttcagcgtt caagaaaatt actcccaata tagatgaaga aggagcaatg     5100

aaagaagatg ctgggatgat ggatgtccat tatagtgaag aggtcttgct ggagttgcta     5160

gaacaatgtg tggatggctt atggaaggca gaacgttatg aaataatttc tgagatttcc     5220

aagttgatcg ttccaattta tgagaaacgt cgtgagtttg agaaacttac tcaagtttat     5280

agaactcttc atggagctta cacaaaaatt ctggaagtta tgcatacaaa aaagagactt     5340

ttaggcactt tcttcagagt tgccttttat ggccaatctt tttttgaaga agaagatgga     5400

aaggagtaca tctataaaga accaaagctc actggcctct cagaaatttc cttgagactt     5460

gttaaacttt atggtgaaaa gtttggtacg gagaatgtca aaataattca ggattcagac     5520

aaggtaaatg ccaaagagct tgatccaaaa tatgctcata tacaagttac ttatgtgaag     5580

ccttactttg atgacaaaga actcacagaa aggaagaccg agtttgaaag aaatcataat     5640

atcagcagat ttgtttttga ggccccttac actttatcag gcaaaaaaca gggctgtata     5700

gaagaacagt gcaaacgccg tacaatcttg acaacttcaa actcgtttcc ttacgtgaag     5760

aagaggattc ctattaactg tgaacagcag attaatttaa aaccaattga tgttgccact     5820

gatgaaataa aagataaaac tgcagagctg caaaagcttt gctcctctac tgacgtggac     5880

atgattcagc tccaacttaa attgcagggc tgtgtttctg tgcaggtcaa tgctggtcca     5940

ttagcatatg caagagcttt cttaaatgac agccaagcta gcaagtatcc acctaagaaa     6000

gtgagtgagt tgaaagacat gtttaggaaa tttatacaag catgcagcat tgcacttgaa     6060

ctaaatgagc ggctaattaa agaagatcaa gttgagtacc atgaagggct aaagtcaaat     6120

ttcagagaca tggtaaaaga attatctgac attatccatg agcagatatt acaagaagac     6180

acaatgcatt ctccctggat gagcaacaca ttacatgtat tttgtgcaat tagtggtaca     6240

tcaagtgacc gaggttatgg ttccccaaga tacgctgaag tgtgaggaaa tgcagatgta     6300

cgtgacaatg agactgacct ttctcaggaa tatttggagc tgtgcaaatg ttaaaattta     6360

aagatttgat atacatggag tgtttcttct cgacaccaaa attttcatgt gttccaacag     6420

ggtgcttaca tatttgtaaa taagcaactt gaaagtgcct ggaaaattgc accactgtgc     6480

ttggtttgta cttttttagg taaatctata tgctgaaaag tagagctcaa aaacagtagt     6540

tcaatttgct taattattgc ttaaaataat ggtactatgt aaaattgtat aatggaatac     6600

aataaaaggt aaaacttatt tgtaattaga agtgaaag                             6638


<210>  236
<211>  2949
<212>  DNA
<213>  homo sapiens

<400>  236
gagctcgccg tcgctccgtc atagagttcg ccccacccca tcccctcctt tctggactcg       60

gagctcagtt cacgcagtaa caaatgaagt gcgcgctgcg acacctccca gcccaccgaa      120

ctccgccgcc atttcctcgc ttggcctaac ggttcggcca atcccagcgc gcatcaagaa      180

ggactgaggc tccgccaatc ggaggccgcc gatttcgacc cttcgcctcg gcccggccca      240

atccaggccc cggccccgcc gcccccggcc cgcccccgcg gtgccctctc tcctccctct      300

ttgtgcgtct cgcgccgccg ccgcccgccg cgtgagagga cgggctccgc gcgctccggc      360

agcgcattcg ggtcccctcc ccccgggagg cttgcgaagg agaagccgcc gcagaggaaa      420

agcaggtgcc ggtgcctgtc cccgggggcg ccatggcgac cggagcgaac gccacgccgt      480

tggacttccc aagtaagaag cggaagagga gccgctggaa ccaagacaca atggaacaga      540

agacagtgat tccaggaatg cctacagtta ttccccctgg acttactcga gaacaagaaa      600

gagcttatat agtgcaactg cagatagaag acctgactcg taaactgcgc acaggagacc      660

tgggcatccc ccctaaccct gaggacaggt ccccttcccc tgagcccatc tacaatagcg      720

aggggaagcg gcttaacacc cgagagttcc gcacccgcaa aaagctggaa gaggagcggc      780

acaacctcat cacagagatg gttgcactca atccggattt caagccacct gcagattaca      840

aacctccagc aacacgtgtg agtgataaag tcatgattcc acaagatgag tacccagaaa      900

tcaactttgt ggggctgctc atcgggccca gagggaacac cctgaagaac atagagaagg      960

agtgcaatgc caagattatg atccggggga aagggtctgt gaaagaaggg aaggttgggc     1020

gcaaagatgg ccagatgttg ccaggagaag atgagccact tcatgccctg gttactgcca     1080

atacaatgga gaacgtcaaa aaggcagtgg aacagataag aaacatcctg aagcagggta     1140

tcgagactcc agaggaccag aatgatctac ggaagatgca gcttcgggag ttggctcgct     1200

taaatgggac ccttcgggaa gacgataaca ggatcttaag accctggcag agctcagaga     1260

cccgcagcat taccaacacc acagtgtgta ccaagtgtgg aggggctggc cacattgctt     1320

cagactgtaa attccaaagg cctggtgatc ctcagtcagc tcaggataaa gcacggatgg     1380

ataaagaata tttgtccctc atggctgaac tgggtgaagc acctgtccca gcatctgtgg     1440

gctccacctc tgggcctgcc accacacccc tggccagcgc acctcgtcct gctgctcccg     1500

ccaacaaccc acctccaccg tctctcatgt ctaccaccca gagccgccca ccctggatga     1560

attctggccc ttcagagagt cggccctacc acggcatgca tggaggtggt cctggtgggc     1620

ccggaggtgg cccccacagc ttcccacacc cattacccag cctgacaggt gggcatggtg     1680

gacatcccat gcagcacaac cccaatggac ccccaccccc ttggatgcag ccaccaccac     1740

caccgatgaa ccagggcccc caccctcctg ggcaccatgg ccctcctcca atggatcagt     1800

acctgggaag tacgcctgtg ggctctgggg tctatcgcct gcatcaagga aaaggtatga     1860

tgccgccacc acctatgggc atgatgccgc cgccgccgcc gcctcccagt gggcagcccc     1920

caccccctcc ctctggtcct cttcccccat ggcaacaaca gcagcagcag cctccgccac     1980

cccctccgcc cagcagcagt atggcttcca gtaccccctt gccatggcag caaagatccc     2040

tccccgcggc ggcgatggcc cgagccatga gagtgaggac tttccgcgcc cattggtgac     2100

ccttccaggc agacagcctc agcaacgccc ctggtggaca ggatggttcg gcaaagcagc     2160

ctgagttatt tttgtggacg gaatcggaac acgctggctc catatcgtga aatttttatt     2220

aatttttttc tttttccttt gttacttctt tatcttttcc tttcttcaga ctccgtccaa     2280

ggagatgctc tccccggtct tctgctgcaa tttagattcc tttcccttct ctccagttct     2340

ccttccctta ccaaggagag gggagcaaat ggttttgggc aagggctttg gccattcatg     2400

tcaagctggt tgtgggtttt tcaaggtgcc atagccaccc ccaaagatgt ttgtttaaag     2460

cgtggggttt tttaatctct gccacccttg tcaagggagt cttgtaaagt tgccgagggt     2520

aggttcatct ccaggtttcg ggattcccat ccgtcctggc gatcctgcca gcagtgggtg     2580

ggcagcctga gctccctcgg gctcgcctgc cagcctggag ttcttcctgt gctccttgat     2640

cacctgagct gcctcagatt ccatttggtc ctctccttcc tggaaggctt ccttttatgt     2700

tttgttttaa tcccaaatgt ctgaatgttt tgcagtgtgt aggggtttga gccccttgtt     2760

cattctcctt cctttttcct cccgcttccc tctccatgaa gtgattctgt tgacaataat     2820

gtatactgcg cgttctcttc actggtttat ctgcagaaat ttctctgggc ttttttcggt     2880

gttagattca acactgcgct aaagcgggga tgttccattg aataaaagag cagtgtggtt     2940

ttctgggtc                                                             2949


<210>  237
<211>  2943
<212>  DNA
<213>  homo sapiens

<400>  237
ctcgcctcca gccccgggac gcggcccgcc accgccgctg ccgccagccc agacgcgccg       60

cccgcatgcg ccgcgaccat ggagcgcccc gaagcgggag gaattaattc caatgagtgt      120

gaaaatgtat caagaaaaaa gaaaatgtca gaggaatttg aagccaatac tatggattct      180

ctggtagaca tgccatttgc tactgtagat attcaggatg actgtggaat cactgatgaa      240

cctcaaataa atttgaagag aagtcaagaa aatgaatggg tcaagagtga tcaagtaaag      300

aagaggaaaa aaaagagaaa agattatcaa cccaactatt tcctgtccat tccaatcacc      360

aacaaagaga ttataaaagg aattaagatc ctgcagaatg caataataca acaagatgag      420

cgactggcca aagcaatggt cagtgatggt tcctttcata ttaccctgct ggtgatgcaa      480

ttattaaatg aagatgaagt aaacattggt attgatgctc ttttggaatt gaaaccattc      540

atagaagaac tcctccaggg aaaacatttg actttgccct ttcaagggat tggtactttt      600

ggaaatcagg ttggatttgt gaagctggca gaaggagatc atgtaaactc acttttggag      660

atagcagaga ctgcaaatag gacatttcaa gaaaaaggca tcctggtagg agagagcaga      720

agttttaaac ctcatttgac cttcatgaag ttgtcaaaat caccgtggct ccgtaagaat      780

ggagtgaaaa aaatagatcc tgatttatat gaaaagttta tcagtcacag atttggagaa      840

gaaatattat atcgcataga tctttgctcc atgctgaaga aaaaacaaag taatggttat      900

tatcactgtg aatcttccat tgtgattggt gaaaagaacg gaggggagcc cgatgacgct      960

gaactagtaa ggctcagtaa gaggctggtg gagaacgcgg tgctcaaggc tgtccagcag     1020

tatctggagg aaacacagaa taaaaacaag ccgggggagg ggagctctgt gaaaaccgaa     1080

gcagctgatc agaatggcaa tgacaatgag aacaacagga aatgagcccg gaacgcaggc     1140

ccccatgtct ctgtgcaaag cctccctgct tccctctgct gagtctaggg actgacttgc     1200

agcgtgctgt ttaagttaag tttctctggt gcaatctgtg aagattgcct aatacttttc     1260

atgatcgatg tgttcgcatt gctgaaacac aacagaagaa aaatggagtg ctgggactgg     1320

cagaggaaat taattgatga aagaagaatg gcccaagttt cattcgccct cagccacgca     1380

caagggaaag ggaactttgg gttatgcctc ctggacgcaa attaaaggcc gagaaagagg     1440

ccttgccatc aatggaatac tgccatttat attgcttagc agggcatttg actactttat     1500

ctgaggccag aactctcaca cacagctatc aagtgctaag tttaaaataa tcactgttgg     1560

aattgtcatc tgtacaatta gtccataatg tttcatgttt gtcctaagtg tgctgttgct     1620

atgcagtgtg atctttattt atagtaaatt atgtttcatg taaatgatat atttttggtg     1680

aaatgcaacc ttttctataa aatgtgggca acattttaaa gtttttttaa aatcctattt     1740

tgataagtca gtatgccata tttaatgaaa tgttattata taattttttt ttcttaggca     1800

agaaacctat tggaattcga gacttaatta atgaagcttt gcatcgagaa acgatgggtc     1860

tgaagtccaa agtgaaacag ataaaggaac ttttattaaa gcctgagact caggccagaa     1920

ttaggaggga gctttttgaa ggaagactta ttaacaacag taattcagca aatgacgttg     1980

atttcagcac aactttgaca taagctctac attgcgattg tgacaacata gcttatgaaa     2040

tcttttcagc ttattaagta gctctttggt aaacaccaaa gaagtttctg atagtgtctg     2100

cacaacagca aaccaacatt tggtgaggaa ttagcaattt cttgccaaag aaaattgatt     2160

ctgcccaatt attttttgag ctacacttgt gttttagaat atctgtttct gtaatattga     2220

gagttatttt atagaaatga tttcttaatt agctgttgtg agatatttct cgggtccttg     2280

cagaaaaaaa catacagact gtgaacaaat cattcacaaa cagaataaaa cagagccaac     2340

aacagtattt taagggtcac ttgcctcctg ttgacacaat tgttgctaaa tcaaaagaag     2400

cgttgtccag gtgtgtctac atctagtgtt acttttaatg agaatttgaa tgtttattga     2460

acaatagtac ttgaatgaac atttataaat gtaattattg cgatcactgg ttaagaatgt     2520

tttatatatc cttataatat ttttcactga tcaaaatgtt gttctgcttt ttcatttctt     2580

aaggaataca tgtttgggat ttttattttt tacgtgtccg aagataagct ccaggtctta     2640

tcgtatccct tgccatctga acttgtttgc actgcttctg tttgaaagag catcttgaaa     2700

aacttccccg gtatgatgat tgttggtaac aactttttct atagtcattg atggagtaga     2760

tcatgatgga ggggaaatca ctggagatca aatatgtaaa atcatttcaa atataaaatc     2820

cagtttactc atggatttta gctatttttt cactgggtaa attatactac atttatttac     2880

aaatgagttt atgcattttc atggctctta ataaacatat tgttttccct tgttaaaaaa     2940

aaa                                                                   2943


<210>  238
<211>  5481
<212>  DNA
<213>  homo sapiens

<400>  238
gcgtcgggag ccgcctctcg cccgcggcgc tcgcccctgc cgcccgccag catcccttgt       60

cccgcggccg cgctcagaca acaaaagcgg aagatgctgc agttgggcaa ggtcaggacc      120

ttgccctgaa gccgggcggc gccgcgcacg cctcttcccg gactgaggag ctgtcgccgg      180

cggagggtgc atgtttgcga ggaagccgcc gggcgccgcg cctttgggag ctatgcctgt      240

tccagaccag ccttcatcag cctcagagaa gacgagttcc ctgagccccg gcttaaacac      300

ctccaacggg gatggctctg aaacagaaac cacctctgcc atcctcgcct cagtcaaaga      360

acaggaatta cagtttgaaa ggctgacccg agagctggag gctgaacggc agatcgtagc      420

cagccagctg gagcgatgca agctcggatc cgagactggc agcatgagca gcatgagttc      480

agcagaagag cagtttcagt ggcagtcaca agatggtcaa aaagatatcg aagatgagct      540

tacaacaggt ctcgagctgg tggactcctg tattaggtca ctacaggaat caggaatact      600

tgacccacag gattattcta caggtgaaag gcccagcctg ctctcccaga gtgcacttca      660

gctcaattcc aaacctgaag ggtctttcca gtatccggcc agctaccata gcaaccagac      720

cctggccctg ggggaaacca ccccttcaca gctcccggcc cgaggcacac aagcccgagc      780

tacgggccag agcttcagcc agggcacgac cagccgcgcc ggccacctgg cggggcccga      840

gcccgcgccg ccgccgccgc cgccgccgcg ggagccgttc gcgcccagcc tgggcagcgc      900

cttccacctg cccgacgcgc cgcccgccgc cgccgccgcc gcgctctact actccagctc      960

cacgctgccc gcgccgccgc gcgggggctc cccgctggcc gcgccccagg gcggttcgcc     1020

caccaagctg cagcgcggcg gctcggcccc cgagggcgcc acctacgccg cgccgcgcgg     1080

ctcctcgccc aagcagtcgc ccagccgcct ggccaagtcc tacagcacca gctcgcccat     1140

caacatcgtc gtgtcctcgg ccggcctgtc cccgatccgc gtgacctcgc cccccaccgt     1200

gcagtccacc atctcctcct cgcccatcca ccagctgagc tccaccatcg gcacgtacgc     1260

caccctgtcg cccaccaagc gcctggtcca cgcgtccgag cagtacagca agcactcgca     1320

ggagctgtat gccacggcca ccctccagag gccgggcagc ctggcagctg gttcccgagc     1380

ctcatacagc agccagcatg ggcacctggg cccagagttg cgggccctgc agtccccaga     1440

acaccacata gatcccatct atgaagaccg cgtctatcag aagcccccta tgaggagtct     1500

cagccagagc cagggggacc ctctgccgcc agcacacacc ggcacctacc gcacgagcac     1560

agccccatct tcccctggtg tcgactccgt ccccttgcag cgcacaggca gccagcacgg     1620

cccacagaat gccgccgcgg ccaccttcca gagggccagc tatgccgccg gcccagcctc     1680

caattacgcg gacccctacc gacagctgca gtattgtccc tctgttgagt ctccatacag     1740

caaatccggc cctgctctcc cgcctgaagg caccttggcc aggtccccgt ccattgatag     1800

cattcagaaa gatcccagag aatttggatg gagagacccg gaactgccgg aagtgattca     1860

gatgttgcag caccagtttc cctcggtcca gtctaacgcg gcagcctact tgcaacacct     1920

ctgttttgga gacaacaaaa ttaaagccga gataaggaga caaggaggca tccagctcct     1980

ggtggacctg ttggatcatc ggatgaccga agtccaccgt agtgcctgtg gagctctgag     2040

aaacctggtg tatgggaagg ccaacgatga taacaaaatt gccctgaaaa actgtggtgg     2100

catcccagca ctggtgaggt tactccgcaa gacgactgac ctggagatcc gggagctggt     2160

cacaggagtc ctttggaacc tctcctcatg cgatgcactc aaaatgccaa tcatccagga     2220

tgccctagca gtactgacca acgcggtgat tatcccccac tcaggctggg aaaattcgcc     2280

tcttcaggat gatcggaaaa tacagctgca ttcatcacag gtgctgcgta acgccaccgg     2340

gtgcctaagg aatgttagtt cggccggaga ggaggcccgc agaaggatga gagagtgtga     2400

tgggcttacg gatgccttgc tgtacgtgat ccagtctgcg ctggggagca gtgagatcga     2460

tagcaagacc gttgaaaact gtgtgtgcat tttaaggaac ctctcgtacc ggctggcggc     2520

agaaacgtct cagggacagc acatgggcac ggacgagctg gacgggctac tctgtggcga     2580

ggccaatggc aaggatgctg agagctctgg gtgctggggc aagaagaaga agaaaaagaa     2640

atcccaagat cagtgggatg gagtaggacc tcttccagac tgtgctgaac caccaaaagg     2700

gatccagatg ctgtggcacc catcaatagt caaaccctac ctcacactgc tctctgagtg     2760

ctcaaatcca gacacgctgg aaggggcggc aggcgccctg cagaacttgg ctgcagggag     2820

ctggaagtgg tcagtatata tccgagccgc tgtccgaaaa gagaaaggcc tgcccatcct     2880

cgtggagctg ctccgaatag acaatgaccg tgtggtgtgc gcggtggcca ctgcgctgcg     2940

gaacatggcc ttggacgtca gaaataagga gctcatcggc aaatacgcca tgcgagacct     3000

agtccacagg cttccaggag ggaacaacag caacaacact gcaagcaagg ccatgtcgga     3060

tgacacagtg acagctgtct gctgcacact gcacgaagtg attaccaaga acatggagaa     3120

cgccaaggcc ttacgggatg ccggtggcat cgagaagttg gtcggcatct ccaaaagcaa     3180

aggagataaa cactctccaa aagtggtcaa ggctgcatct caggtcctca acagcatgtg     3240

gcagtaccga gatctgagga gtctctacaa aaaggatgga tggtcacaat accactttgt     3300

agcctcgtct tcaaccatcg agagggaccg gcaaaggccc tactcctcct cccgcacgcc     3360

ctccatctcc cctgtgcgcg tgtctcccaa caaccgctca gcaagtgccc cagcttcacc     3420

tcgggaaatg atcagcctca aagaaaggaa aacagactac gagtgcaccg gcagcaacgc     3480

cacctaccac ggagctaaag gcgaacacac ttccaggaaa gatgccatga cagctcaaaa     3540

cactggaatt tcaactttgt ataggaattc ttatggtgcg cccgctgaag acatcaaaca     3600

caaccaggtt tcagcacagc cagtcccaca ggagcccagc agaaaagatt acgagaccta     3660

ccagccattt cagaattcca caagaaatta cgatgagtcc ttcttcgagg accaggtcca     3720

ccatcgccct cccgccagcg agtacaccat gcacctgggt ctcaagtcca ccggcaacta     3780

cgttgacttc tactcagctg cccgtcccta cagtgaactg aactatgaaa cgagccacta     3840

cccggcctcc cccgactcct gggtgtgagg agcagggcac aggcgctccg ggaacagtgc     3900

atgtgcatgc ataccacaag acatttcttt ctgttttgtt tttttctcct gcaaatttag     3960

tttgttaaag cctgttccat aggaaggctg tgataaccag taaggaaata ttaagagcta     4020

ttttagaaag ctaaatgaat cgcaagttaa cttggaaatc agtagaaagc taaagtgatc     4080

ctaaatatga cagtgggcag cacctttcta gcgtgagctg tagagtaacg agaagtgctt     4140

tatactgaac gtggttgatg ggaggagaga cgaggcattc gggccggtgg ggcgtaaggg     4200

ttatcgttaa gcacaagaca cagaatagtt tacacactgt gtgggggacg gcttctcacg     4260

ctttgtttac tctcttcatc cgttgtgact ctaggcttca ggttgcattg gggttcctct     4320

gtacagcaag atgtttcttg ccttttgtta atgcattgtt gtaaagtatt tgatgtacat     4380

tacagattaa agaagaaaag cgcgttgtgt atattacacc aatgccgccg tgtttcctca     4440

tctatggttc taaatattgc ttcaatttca aacttttgaa agatgtatgg atttccagtt     4500

tttctttact ttctcccagt atgttttaac aaaaaaaaaa aaaagcagga aaaaaggaat     4560

atttagcagt attgttcgtt ctgatatgtg aatttgtttg tgacaactaa acaaggcatt     4620

cagcagtttc tgacaattaa catacatcat tccacactcc ttgtcaacaa agtgcttttt     4680

cactgcctaa aattttagat gtagatattt gaaatagatt ttttcattta taccagtttt     4740

ctttatgatg atacagtgtt aaaagaaaat aaattacaat tgatctgtca tccatatttg     4800

ctaagaatgt ctatttccaa gaacctatat cttacaaaat acacattctt gcttgtgtgt     4860

ctgtgtgtgt gggtgtatgt atgtccacgt actagaaaaa ttacctgtgt gagattttat     4920

tttgacagaa gctatttcat ttgctgttca tcttgtacaa actttgtttt tggtttttta     4980

gtataaatgt acatcagttt gttccttttg tactgtatct attcttctga ccatctagtg     5040

actcaggata ttaggccagt tgaagtggag ttataggatt ttcacacatt cacgcatact     5100

tggatatcaa ccctctctac aggtccgttt ccttacacat tttatcccct cagaacacga     5160

taaaccatgg ccaattcagt ttcactttgg ggccaattac ttgaagtatc cacagaaaat     5220

gtaaactgct cgccttattc ccccaaactt tttgttcatg tggcagggag cagtacacaa     5280

ctatggaata gattattaaa actgaacttg aagctaacgt tagaatagtg gttaacagag     5340

ctaagaaata aggctaacca tcgaaaagaa catgggccgc gggtaaacta gctttgctct     5400

ttagatgcaa gtggctgagg ccaataggtg cctagtaaat gttaactgtt cttggaaaaa     5460

ataaaaacat cagtaacaaa a                                               5481


<210>  239
<211>  13760
<212>  DNA
<213>  homo sapiens

<400>  239
ccgcggcgcc gggacagccc cgggactctg ccaggtggat gttgtgcgta gccggagcca       60

ggttgaagag agaactcgat gccaccgcaa cggtattggc gaaccggcag gatgaaagtg      120

agcagtccag aaagcggctt atcgaacaga gccgggagtt caagaagaac actccagagg      180

atttgcgcaa gcaggtagcg ccgctgctga agagtttcca aggagagatt gatgcactga      240

gtaaaagaag caaggaagct gaagcagctt tcttgaatgt ctacaaaaga ttgattgacg      300

tcccagatcc cgtaccagct ttggatctcg gacagcaact ccagctcaaa gtgcagcgcc      360

tgcacgatat tgaaacagag aaccagaaac ttagggaaac tctggaagaa tacaacaagg      420

aatttgctga agtgaaaaat caagaggtta cgataaaagc acttaaagag aaaatccgag      480

aatatgaaca gacactgaag aaccaagccg aaaccatagc tcttgagaag gaacagaagt      540

tacagaatga ctttgcagaa aaggagagaa agctgcagga gacacagatg tccaccacct      600

caaagctgga ggaagctgag cataaggttc agagcctaca aacagccctg gaaaaaactc      660

gaacagaatt atttgacctg aaaaccaaat acgatgaaga aactactgca aaggccgacg      720

agattgaaat gatcatgacg gaccttgaaa gggcaaacca gagggcagag gtggctcaga      780

gagaggcgga gaccttaagg gaacagctct catcggccaa tcactccctc cagctggcct      840

cacagatcca gaaggcacca gacgtggagc aggccataga ggtgctgacc cgctccagcc      900

tagaagttga gttggccgcc aaggagcggg agatcgcaca gctggtggag gacgtgcaga      960

gactccaggc cagcctcacc aagctgcggg agaattcggc cagccagatc tcacagcttg     1020

agcagcagct gagcgccaaa aacagcacac tcaaacaact ggaagaaaaa ctcaaaggcc     1080

aggctgacta tgaagaggtg aagaaagagc tgaacattct gaagtccatg gagtttgcac     1140

cgtccgaggg cgctgggaca caggatgcgg ccaagcccct ggaggtgctg ttgctggaga     1200

agaaccgctc gctgcagtcc gagaacgccg cgctgcgcat ctccaacagc gacctgagcg     1260

ggtcagccag gaggaaaggg aaagaccagc ctgaaagtcg gcgcccggga tctttgccgg     1320

ccccccctcc ttctcagttg ccccgcaacc cgggggagca ggcttccaat actaatggta     1380

cacaccagtt ctcaccagcg gggttaagtc aagacttttt cagctcatcc ctggcaagcc     1440

ccagcctacc cctggcttct acaggaaaat ttgcactaaa ctctcttctc cagcggcagc     1500

taatgcagtc cttctactcc aaggctatgc aggaagccgg aagcacaagc atgatttttt     1560

caacaggtcc atacagcaca aactccatat cttcccaaag tccattacaa caaagcccag     1620

atgtcaatgg catggcccca tcccccagcc agtcagaaag tgctgggagc gtctccgagg     1680

gcgaggagat ggacactgca gaaatcgccc ggcaggtcaa agagcagctg attaagcaca     1740

atatcggaca acgtattttc ggacattatg tgttgggact gtctcaaggg tccgtgagcg     1800

agattctggc ccggcccaag ccatggaata aactgactgt tcgtggcaag gagccatttc     1860

acaagatgaa acagttcctc tccgatgagc agaacatcct ggccctccgt agcatccaag     1920

gcagacaaag agagaatcca ggccagagcc tgaacagact atttcaggaa gtaccgaaac     1980

gaagaaatgg gtctgaaggt aacatcacca cccggatccg agcctcggag actggctctg     2040

atgaagccat caagtccatc ctagagcaag ccaagaggga gctccaagtg cagaaaactg     2100

cagagccggc ccagccttcc tccgcatccg gcagcgggaa ctctgatgac gccatccgct     2160

ccatcctgca gcaagcccgc cgggagatgg aggcccagca ggctgccctc gaccctgcct     2220

taaagcaggc accactgtcc cagagtgaca tcaccatcct cacccccaag cttctgtcca     2280

cctcgcccat gcccaccgtg tccagctacc cacctctcgc catctccctg aagaagccct     2340

ccgcagctcc tgaggccggt gcctctgctc tgccgaaccc cccggccctc aaaaaggagg     2400

cccaggacgc ccccgggctg gacccccagg gagcagccga ttgtgcacaa ggggtcctga     2460

gacaggtgaa aaatgaggtg ggccgcagcg gtgcctggaa ggaccactgg tggagcgcgg     2520

tgcagccgga gagaagaaat gccgcctcct ccgaggaggc caaggccgaa gaaacgggcg     2580

gcgggaaaga gaagggcagc ggtggcagcg gaggtggcag ccagcctcgg gccgagcgca     2640

gtcagctcca gggaccctcg tcgtcagagt actggaagga gtggcccagc gctgagtccc     2700

catactccca gagctcagag ctgagtctga ccggggccag ccgcagcgag acaccacaga     2760

acagccccct gccatcctcc ccgatcgtgc ccatgtccaa gcccaccaag ccctcggtcc     2820

ccccgctgac ccccgagcag tacgaggtct acatgtacca ggaggtggac accatcgagc     2880

tcacccggca ggttaaggaa aagctggcca agaacggcat ctgccagaga atcttcgggg     2940

agaaggtgct gggcctgtcc cagggcagcg tcagcgacat gctgtcccga ccgaagccat     3000

ggagcaagct gacgcagaaa ggccgagaac ccttcatccg gatgcagctc tggctgaacg     3060

gcgagctagg ccagggtgtt ctacccgtcc agggccagca gcaagggcca gtcctccact     3120

ccgtgacatc gctccaggac ccgctgcagc agggctgtgt gagctcagaa agcactccaa     3180

agacctccgc cagctgcagc cctgcccctg agtccccgat gagttccagt gagtcggtga     3240

agagcctgac cgagctggtc cagcagccct gtccccccat cgaggcgagc aaggacagca     3300

agccaccaga gcccagtgac ccgccagcat ccgactccca gcccacaacc ccgctgcctc     3360

tctccggaca ctcggccctc agcatccaag aattagtagc catgtccccg gagctggaca     3420

cctacggcat aaccaagcgg gtgaaggagg tgctgacgga caacaacctc ggccagcgct     3480

tatttgggga gaccatctta gggctcaccc aaggctctgt ctctgacctc cttgcccgcc     3540

ccaaaccctg gcataagctc agtctgaaag gacgagagcc cttcgtccgg atgcagctgt     3600

ggctgaacga ccccaacaat gtggagaagc tgatggacat gaaacggatg gagaagaaag     3660

cctacatgaa gcggcggcac agctcagtca gtgacagcca gccctgcgaa ccgccctctg     3720

tcggcaccga gtacagccag ggcgccagcc cccagcccca gcaccagctg aagaaacccc     3780

gggtggtgct ggctccggag gagaaggagg cgctgaaacg agcgtatcag caaaagccat     3840

acccgtcacc aaaaaccatc gaagacctcg ccacccagct caacctgaaa accagcaccg     3900

tcatcaactg gttccacaac tacaggtctc ggatccgcag agaactgttc attgaggaaa     3960

ttcaggccgg gagtcagggc caggcgggcg ccagcgactc accctcggcc cgcagcggcc     4020

gggcggcgcc cagctcggag ggcgacagct gcgacggcgt ggaggccact gagggcccag     4080

gcagcgccga caccgaggag cccaagtctc agggagaggc cgagcgggag gaggtgccgc     4140

ggccggcgga gcagacggag ccgccgccct cggggacccc gggcccggac gacgcccgcg     4200

acgacgacca cgagggaggc cccgtggaag gcccggggcc cctgcccagc cccgcctccg     4260

cgaccgccac cgccgcgccc gcggcccccg aggacgccgc tacctcagcc gccgccgcgc     4320

cgggggaggg ccccgcggcc ccgagctccg cgccgccgcc cagcaacagc agcagcagca     4380

gcgccccccg caggcccagc tcgctgcaga gccttttcgg cctccccgag gccgcgggcg     4440

cccgggactc gcgcgacaac cccctgcgca agaagaaggc cgcgaacttg aacagcatca     4500

tccaccgcct ggagaaggcc gccagccggg aggaacctat cgaatgggag ttctgagggg     4560

ccgcggccct ggggcgggca gccaggctgg gccgcaaggg cctggacggg gtcggacggg     4620

gcaggcgctg cggacaccgt ggcctgggct tggcccgcgg cctgcaccga ccccgggccg     4680

gacctgagcc cgcagcccag accccctcca cggtccgcgg cctgcaccga cccgaggccc     4740

agatccaagg ccgcggccca gacccactct gcggcccggg ccgaccctgc ggcctccacc     4800

aaccccgcgg cccagaccca gcccgcggcc tggacccctg gaccgctttg cgcacttacc     4860

gccctgcggg ccacagggca aaatcgccat aggccaaggt gcatatagaa aacaaaggag     4920

cattaagccc aatctatgtc gtgttttcaa ggaagaaaac ggaaatgtgt ggtcgagctt     4980

ttttgtaccc tgaagtgttt tttttattgc cctaagtgat ttccacaggt tctggaataa     5040

ctcttacagc tttgccttgt gtcctcctgt tccgtgtggg ctttaaaaga aaaaaaatca     5100

aacccacata ttaaaagggg gctttttatc tgccatctaa tggcttcaga gcgataatac     5160

actattatct tcttaaacca ggaaaaaata aaaggggggg tgggattttt cagaaaaatt     5220

aaaaaagaaa gtttttgtag ctgttcagtt gccactaaga gattgcacag tcaaaacgac     5280

tctaaacaca ctagtttgga ttcctaaata ttttcaagaa aagaatcttc tcgtttgaaa     5340

ctttgaatta aaataaaaca catttactcc acatattttt taacaaaaag aaaacgtcac     5400

atcaggaaac tctgattttg tggtagctga catagtgttt tcttgtacgt gaatagaatc     5460

ctgacatgta gtgcacattg atgtatagct ttaactgacc ctgggttttg cagaccaggg     5520

tttgtttaat acactccatt ctaggccaaa tcaggacaaa aaaaagaaaa aaaaagaaaa     5580

aaaaaaaaga aaagatccga atctaggtat tttataatct gctttttaac ctctaaccgc     5640

agagcacgct gatcagacct catatcttgg aggtttagga gacaagttag aactgtagca     5700

tgtacctgtt aattttgttt aatttatggt gtctcaatct gtctgtgcgt ctgcacgtgt     5760

gcaagcattg aaagaaagga gagagtagtc cgggcgagca cagcaggcag ttccagggcc     5820

agacgggccc atccccaagt agatagcagt ctacggatct ctctctggca cagaaggcac     5880

ctcacctcac accactctcc tggatacctg atgaactgag ccctcccagg ggaagacact     5940

ccccaggcct gggcagggct tacacgcgca ctctctctct tctttccctt tttcttccca     6000

ccgcaagcac tgatgaccct gttgaactcg tgggaaactt cctttctctg caggagagag     6060

aacgtggcat tctgggctcc ccactcccat ccctgtagaa atggcccaaa ctcacaccaa     6120

aacgtggatg ctcttcaact tccaaaccta ccatttgccc ttctttcatt tcgcctctta     6180

gttcttttta tgcacagttt tagggcagtc taagtacaaa ctgaaagtct aacttgtctc     6240

tgattcctcc cttgtctatg tgtatatgcg tgagaataga ggcgggtgag agtgtgcgtg     6300

cgtgtgcgtg tgtgcaattt tatacgtctg tgtattttct taagtacctg tgcacacgta     6360

gagtgcatta ctgccacctt tttcaataag ctgttttatc agttacggct tctacaagtt     6420

tgctaattta gacttcttta ttgccatatc tttaaactaa caatagatga tttcggtata     6480

tatatatatt tttttttgct tatttatagg tgctgtattt tattatctga ttgttaggaa     6540

gggatgaaag gggcaaatat tctttagagg gatagactgc cggcagtatt gggtataatt     6600

tacaagatgt agttgtcata ctgtatatta ctgattgaaa actttttgac cgtattgtgt     6660

atcattgaaa cctttgtctt aggtcaacat ctttggatga cattttaatg gtgcattcat     6720

tatttcttaa gtttaattaa tattactttt ttttttattt ggggggtggg agggagttat     6780

aattttaaag gtatgctctg gctgttccac ctccgtgtgc ttgttaatta acttgtagga     6840

ctttgactgt aagatgtgaa accacgtttc ttgcatgatg ttttagagat tatttcattt     6900

acagtctttt aacctgcagc tgcagcactt agttcacgtt ttcacaaatt tcaagagtca     6960

ctacactaaa gacaatgcct tttcatgaat aagaagtttt cagaaggctc tagggggctg     7020

ggaggcaggc tgttcgtttg tcttttgttg ggggtatcat ttctgaactt gaaatccagt     7080

tcagggagaa gagaattcaa aattagagga gcttaagggg acacgggtca acatctagct     7140

cgattcaggt gcattgagaa gagtgagttc acatcggtga cccttaggac agtgagtggc     7200

agagccctga cgactgtggt gtcctctcca caaaaccctc aagggacttt tgtcatcatg     7260

tgtgatgaat ctttaaatat cgtctaattt tcataagaat gaaaagaagt taacaggaaa     7320

tagtaggcta gggtttagtt ttaaaggcat gactgttatt tacaaaggtg ttaaatctga     7380

ggaaattgac aaatacagat ttgtccattc tagtggccaa acagtaacag tctaaaatgc     7440

agtcattttg accctcccaa gcaatttagt catatgtgtt gttttctctt ttctgttttt     7500

acttcttaga tttttaacta ggttactgtt ggttcccatt ctgtcttttt tgccagactt     7560

acatctggtg ccagatacaa tcagttggtt aaattttgct tgcagttctg tgtatttttt     7620

ttcctctatt atttattttt ttaaaaaaaa tagagatcct aaccttagat ctttgatgtg     7680

aagctagcac tgtctgtaat acttctaaga gctgccacta aaataataca gcaatccgtg     7740

gccaggggag caccccctcc tggttgggcc cctcagttgg agtctaaggg ttaatctctc     7800

atcttgctaa gcagtattca agtgccttga acagtgtccc ctcggcatgg ctccccttca     7860

gcaggctggc attccaagca gtggcccccg caggcagccg acccccttcc tcttcacgct     7920

ctatgagttt aaaaagctga tttgtacctc tcccctgggg gaaacggttc catataaaac     7980

actaacactt aattacaagc tccattatgc cattttaaat ggcttctttt tgttaattgg     8040

aggcattgtt cataacttaa ggcttttgcc attaacttag ctggctaagc agaggctcgg     8100

ggtaaaatca gtgtttgcat ttagcctctt gacccggagt tccggcccaa gctcccttgt     8160

gatagccgag atggcaggtg tgtgagttct gtcctagacc tgtgcccaac tcacttccac     8220

cccagaggag tcttctgtcc tcctccccaa cccccgagct ccctggtaac ctcctcttga     8280

acttctgtat cagtgaagac atctgtggtt tctgctcacc agacctctct ttagaaaggg     8340

ttatcagagc catggagctt agctcaattg gattcttcta gacgatctta ggaggcatct     8400

tggcatgagg cagcttctaa gcgtctcctg ggacaggatt ggggtgacag cccagggatg     8460

catgcatggg agaactctct gagaaatgcc aggatcgtgg ctcacaggga cccaccatca     8520

aaacctgcta ctttgtgcaa gtaattgagg caaaagatac cagtcgacag cctccctggg     8580

gtagatccct tgtacctcca aagtacaaat acctccctgc tcagtttcct tcctgtcgcc     8640

atctttgttt tcttcccatt gaaaaaccat cctgtctgat gtggacgttc aggtctgctg     8700

gttggcggtc cgggcccaga gtgcagcaga gctctgggtt aaatattcct ttctggccac     8760

cgcccaagcc caggtggcca gctctcatac cccatctccc tccttggcca gggccagcat     8820

caggcgtgca gctcatgacc agtttacaca ggctgcaaag agatcgctgt gggcctcggc     8880

tgactacttt aagattatgc cacagccagg ccctaaaaag agaggggaac aggagtcccc     8940

aggtgagctc tctgacgggc aggtgccttc ccgactaagg ttggactgga tgactttgtt     9000

cctcctgcat gcatgtcctt tgatgcaagg gtgatcaatg aactctgttg acattctatg     9060

caatgttttt cattcctctg attttagcaa agcaaatctt actgaaaaat agcagagcca     9120

ggggaacaga cgcatgtcct tctgggagtc acacaaaagc agagagattt tgaactgagg     9180

ggcgacagcc tttgccttaa atgcagtatg acaggcgctt cttggcagac cagtaaaaac     9240

aaaagcccat agaccttact catcccaagg ccgacaagcc agctgtacag ggcgagatgt     9300

agcaacacgg ggcatgagcg gtgggcgtgc tgggctattt gctgtggtac tttaggctgg     9360

aggtttggct cctgtgctgc cggtgggggg ccctgtccct ccccagatgt cctccctctt     9420

cttcacactc ctcattgtcc cttctacctc actaacctgt cttctccatc tgatgtcacc     9480

cagaaccaca ccccacagaa ctgtgaggca cgtgggctgg agagagcaga aaagctgcca     9540

gcgcagcaga cacgaacatc cctctgcctg gtgggccggc tttgtgtgtc tctccttttg     9600

tgagcgcaac acggacaaac agctgtgctc tgcaaggcac acggatgttt cccttccacc     9660

tgttcccaaa gctccagcag ctgtttcttt tgcaggcagg gcgtggtctc ggggctccga     9720

gggtcttgtc tttggtccgc cttcctttct gtccagtcct gctcagctgt taagatccat     9780

catggccatt atccttgtcc cggactgccc caaagttccc agctggcttt ggggaacact     9840

gtagctcttg ggtgtctctt gtctctggca tggttttagc gtcactgcga acactccttt     9900

gcaaacatca aacatctcaa agacggaaaa ggatagatgg cttcctccag cctacacgcc     9960

ccgtccacag tggcatcacc ctcttatccc aaaagaatat gccagttccc atccagcacc    10020

gaagaaaatc agctcctggg gctggtggtt ggaggtgggt ctgtccactg tgggggccaa    10080

agtgttcccc tgctggagac agtttgcaag taagaaccta aggatgggga cagcatcctg    10140

tgcttgggca ttgaccagcc aaagctcaca tttagaaagc cctcagtgct tctgtggttt    10200

cacctgggca tcgacgacat tagggaagcc tttgtgacca caagggcagg gcttgtgccc    10260

tgagtggcga ggtggtgacc tgaggccagt gtgatgtggt tggatctcag cgtgtactga    10320

atgccagtct ggccggcaca ctcgaacgct aagagaatgg tccaatttga tgatcttatt    10380

tctatttcga tcaggttttg actttttgta gatgaaaact accagggaaa aggggaagca    10440

ggtacccaat aaagtttaga aagatccagt ctgtgaaacc cttagagatg ggctgaaagt    10500

taagtccacc aacccttggg cttaatcagg acggaagagg agggggtgtg gggggcagag    10560

cgtaaaacaa gccccagccc tactcccggc cccccagccc agtcttccca atcccagagg    10620

ccccggcggc ctgtgctcct caccaccctg gtcaggggaa tagaaggaaa tgcaatttcc    10680

gcctgtctgc ccgacttcca aaaactgcct cctcctgccc aggcctctcc caccaccacc    10740

ttccctccaa agataaccgt gtccatgcca tccgtggcat catctcgagt tttcattttt    10800

ggatgaagtg acatttagct ttaacaagac atttccaaag cgcctagtct cctccaaaat    10860

gctaacttta aaagttgggc attgtaggcg aaaaatccca aaaaaaaaaa aagacaaaaa    10920

aaaaaggctg gcgagagaaa gacatttggc tatgcataaa tgtgcacttc ccccatgccc    10980

ccgttcttaa actcttaaga tgcctttgag ttgcttttca tgaatccttt tagtttaccc    11040

gataatgtta agaaagcatt agtctacgtt actgtaattt ctgtagtgtt tacgctttaa    11100

tttctaccac aaaatatgct atatgctatg tatcaagctt tctgtaatca gaaagaaaag    11160

gtgccttata tcccaatgtc acggctacat ccctatggaa attaatcaga agcacagtgt    11220

gtacggaagc attgggactt ctgctggtga aacaagagac cattcagcaa gacacattga    11280

agtggcacgg agctgctttt gttttataat tcttttttcc ccccttttcc ttcttctttt    11340

ttattatttt attatttttt ttgtactttg ctttaaacgg aaagcactta aatagatgac    11400

tatgtgtaaa agctctgtgc aattgaaatc atttttcttc attttaaaaa aataacgtat    11460

tgcacaccaa atgaactcaa agtaagcttt agaccaggac gattcaggtt atgaatgagt    11520

ttgttcactg tagttccgtt tgttcatgaa ccgaagggaa aacaggcctc cccgactccc    11580

tccagtctcc cagcctgcct cttggtgacc actgtgctgg gcgtgcaggg cccgcgggct    11640

ctggccggag ccgctggcct gacgaggcag gatagggagt atccgtgatt cagaagctga    11700

gacccttccc cagtgtctga ggccacagcc atcccttcca gcacttaatc ttgtcttgtt    11760

gaaatggact gactgctact gacctgccgg cgtgcgtgag ggtgattata aaaggatgtt    11820

tccttgagaa aaaaaaaatt atttctatcc tcttctattt attattaggt taatcattta    11880

agtacttatc aggagtgtat tgttattttg tgttttgttg tcataaatgc tttttgctgt    11940

cactctagtg gttactatcc tctgccttcc tctcctcccc tactccccca gagaaccaag    12000

gcgtctgggg gattgactgg ggggcagagg gggtttcccc agcaaaatca aacacctgtc    12060

tccagagtag ccactcaaaa actggtggtc tctatgtgtc taacttttta aatgagagtg    12120

tttatgaaca aaaaaattta ccaacgtgtg agggagttgc tgagttgaag aatgctcgct    12180

tgaggagctt cagaggaatc ttagcaaagc caagttcagt tccccaaagc ctcctagagc    12240

ctctggtaag acttctgggt tcatgaagtt tcggcgagcc gtggtcagag agggcgcggt    12300

ggcctggcca agactttacc tccaagcgag agagtgattt cttgcaaggc ccgcatgggt    12360

tgatacgttt tggttggttt tttgttgttg tttttcttgc gtacaaagtt ggtcaaaacc    12420

atctttcaaa gcaacagtgt tttgtagtac caggctgtgg cttgagggct cacctaggag    12480

atcataggca gagggcccct ttcccctata ggtggttcaa cgtggaggaa ggttgggtgt    12540

ggagattgct tgctgtggcc ccaagctcag ccagcaggac acccagttgt tgccaatcag    12600

gtgtgaaggt gaggcgccct gccttgatcc catgggccca gcagaaggaa acttacccca    12660

ggccaaggca agggccctgc tcaccccaag gtaggctggg aagagcatct ctttccatat    12720

catcacctcc ccttctccaa gattgccggg ggccctgatt ttgttctctc tttgaaagaa    12780

accctccacc gaaacaatgg tccccatctc cccagaagcc tttttttttt tcatttttct    12840

ctaattagtc tatgcatttc tctctctcaa accatcttct gcctcttccc ttgagaaaac    12900

gggcatctca cgtaccccca tctgagacct cttggaaaaa aaaaatcccg tgtattctgg    12960

agatgtgaga attcacccaa aattcttaaa acattggaga atagcttgtt ataaaataaa    13020

agtgggggta aaaagaaggt ggttttcccc acatcccttt gcattgaata agagacctag    13080

ttctttgcgt ttgtgcaata actctttgct gcttgccttg agagcgggta gcaccacgct    13140

cctgtccaga ctactaacag cacaagacgc actcacaggg tggcggaatc ttccggaaaa    13200

ctctctataa gctcagctcc ccccacccca cccccactct agcgttttgt cacgtcttac    13260

attttagcag tattttatat tttctgtaac gcaccaagtc ttagatcttt ctagagcttg    13320

tttgttcatc ctcacaatca cagatttttt tctccaatcc tcacagagac ccaattgacc    13380

aaaaaagaaa aaaggaaaaa aaaaaagtcg tctttttttt ttttttttgt acaaatcgct    13440

ttgagatgcc tctggtgtgt tgctgtgtga catctctctg gtaacatttt atttcttgct    13500

atttgttttt ctacattaag agtcaaagtt gacctggctg gcgtgggggt gggggaggca    13560

cccgtcggcc ccttggtgtt gtccctctgt ctttggttag ccatacgatg tttgttctca    13620

gcactgtaca acggtcccta tataatacgg agaagcaata tcactgtatg agactcacac    13680

catgtattat tattcactag caccctaggt gtgataattg aagtaaatat cttttataca    13740

aacacaaaaa aaaaaaaaaa                                                13760


<210>  240
<211>  2666
<212>  DNA
<213>  homo sapiens

<400>  240
ggggcggacg ccgctcgccg gctggcccca tcctccactg cagcagtaac gtcgcggcgg       60

gttgcgggta ggactggacg ccagagcagc cgcgcagcgc ctgaaccgct gcgggccgcc      120

gcggccgccc cttcccaccc tcgcctctgc tgtctccagc ctcgcttctc cgactttcct      180

gctcctctgc tgccttcgtt tctggtcctc ggccgtcctc gccgcccgcc cagaggagtc      240

cccgcgcccg ccaagaagcc gctttccgct ggcccgcagc cgccgcgact tcggcacagt      300

ttctccctct ggctagtctc ccaaacggcc gctcctcgcc cgcgggaaga ccaggctgcg      360

accgcgaacg cccgatcctc tccaggagcc gcagcgagcg cccggcggcc acgccccgcg      420

accacacccc ggcggctctc ggcccagcgc gcctgccttc gccgcccgcc gtcgctcctc      480

gcccgctgca cgacgacgcg acgcccctgc tgcaggcggc ggacccgacc ggacccagac      540

ccagacgcaa gatggcgacg gccgcgtgac tgcctcagcg tccccgagct cggctccgag      600

tgcacctacg gactgactgt gggggcagag aagggcgaga tcaggactct gtctttgtta      660

atcgtgactg catgaaggtc gcctccctcg ggcctacttg gtgggagtgt ctggtattgt      720

tctaaggcca ggagcacggt gagccacagt ctgttggtag aatttggcgt cttgatagtt      780

gagaaaatgg cgatgacact gttggaagac tggtgccggg ggatggatgt gaactcccag      840

agagctctgt tagtctgggg catcccagtg aactgtgatg aggctgaaat cgaagagacc      900

ctccaggctg cgatgcccca ggtctcctac cgaatgcttg ggagaatgtt ctggagggaa      960

gaaaatgcga aagcagcctt attagagctc actggcgctg tagattacgc cgcgatcccc     1020

agggagatgc cgggcaaagg aggggtctgg aaagtgttat ttaagccccc aacttctgat     1080

gctgaatttt tagaaagatt gcacctcttc ctagctagag aggggtggac cgtgcaagat     1140

gttgcccgtg tccttgggtt tcagaaccct actccgaccc cgggcccaga gatgccagca     1200

gagatgctaa actatatttt ggataatgtt attcagcctc ttgttgagtc catatggtac     1260

aagaggctga cacttttctc ggggagggac atcccagggc ctggagagga aacctttgat     1320

ccctggctgg agcacactaa tgaggtccta gaggagtggc aggtgtccga tgtagaaaag     1380

aggcggcggt tgatggagag tcttagaggc cccgccgctg atgttattcg catccttaag     1440

tccaacaacc ccgcgataac cactgccgaa tgcctgaagg cgcttgagca ggtgtttggg     1500

agcgttgaga gctctaggga tgcccagatc aaatttctga acacttatca gaacccggga     1560

gaaaaattgt ctgcttatgt cattcgtctg gagcctctgc tacagaaggt ggtagagaag     1620

ggggccattg ataaagataa tgtgaaccag gcccgcctag agcaggtcat tgccggggcc     1680

aaccacagcg gggccatccg aaggcagctg tggcttaccg gggctgggga agggccagcc     1740

ccaaacctct ttcagttgct ggtgcagatc cgtgaggagg aagccaagga ggaggaggag     1800

gaggctgagg ccacccttct gcagttaggc ctggaagggc acttctgagt gccaggaaag     1860

gcagctttag tgcagaccta gatcacagct acttttcttg tccctgtggg gtcttacaga     1920

tgtgtctctg agtagtaaag gcttagcctt gttctgtttt gttgtttttt ggaggggaag     1980

gttagtcagg cctgagtatt catgtaacat tctaaaattg tgccagcgag caccgtgaac     2040

gactgcaatg caagcgggtc ttgctggcta aaatgccagg taaagggttg gttggacaca     2100

gcgcttagtg cacgctgtca tcatggacat cataatcagt tgtgaaaaac acgcgaacct     2160

atgacacttc ttattccaca ctgaatgtga aattgcatgt tcagatgttt actacgaggc     2220

ctggctcaca ggaagtgttc agtaaaagta tgcactgtta gattactgat aacgcggata     2280

gatttttgtt taccataaat tgttccagat ttatattaat ggaaggaagt gtgcatttat     2340

tagctattac tcaactttac aatgcaaaca tcttatttct catctttaaa catgtcgacc     2400

agtttaattg aaaagtattc tgagactgca aaatggggtg ttaaaaaata ctgcagttac     2460

ggagctgtgt aaaccagttt ctcattgcat aagatacaga tgtaaattgc atggagaggt     2520

tgatatgcac ctgtacagta attcactccc ccatttcaca tctttgtcag agaatagttc     2580

ttgttcatac tgagtgttct aaatttgaag ttatatatac aaattaaaat attttaaaaa     2640

ttcaaaaaaa aaaaaaaaaa aaaaaa                                          2666


<210>  241
<211>  2414
<212>  DNA
<213>  homo sapiens

<400>  241
agtccctgcc ctcccctggg gagggtgagt cacgccaaac tgggcggaga gtccgctggc       60

ctcactccta gctcatctgg gcggcggcgg caagtgggga cagggcgggt ggcgcatcac      120

cggcgcggag gcaggaggag cagtctcatt gttccgggag ccgtcaccac agtaggtccc      180

tcggctcagt cggcccagcc cctctcagtc ctccccaacc cccacaaccg cccgcggctc      240

tgagacgcgg ccccggcggc ggcggcagca gctgcagcat catctccacc ctccagccat      300

ggaagacctg gaccagtctc ctctggtctc gtcctcggac agcccacccc ggccgcagcc      360

cgcgttcaag taccagttcg tgagggagcc cgaggacgag gaggaagaag aggaggagga      420

agaggaggac gaggacgaag acctggagga gctggaggtg ctggagagga agcccgccgc      480

cgggctgtcc gcggccccag tgcccaccgc ccctgccgcc ggcgcgcccc tgatggactt      540

cggaaatgac ttcgtgccgc cggcgccccg gggacccctg ccggccgctc cccccgtcgc      600

cccggagcgg cagccgtctt gggacccgag cccggtgtcg tcgaccgtgc ccgcgccatc      660

cccgctgtct gctgccgcag tctcgccctc caagctccct gaggacgacg agcctccggc      720

ccggcctccc cctcctcccc cggccagcgt gagcccccag gcagagcccg tgtggacccc      780

gccagccccg gctcccgccg cgcccccctc caccccggcc gcgcccaagc gcaggggctc      840

ctcgggctca gtggttgttg acctcctgta ctggagagac attaagaaga ctggagtggt      900

gtttggtgcc agcctattcc tgctgctttc attgacagta ttcagcattg tgagcgtaac      960

agcctacatt gccttggccc tgctctctgt gaccatcagc tttaggatat acaagggtgt     1020

gatccaagct atccagaaat cagatgaagg ccacccattc agggcatatc tggaatctga     1080

agttgctata tctgaggagt tggttcagaa gtacagtaat tctgctcttg gtcatgtgaa     1140

ctgcacgata aaggaactca ggcgcctctt cttagttgat gatttagttg attctctgaa     1200

gtttgcagtg ttgatgtggg tatttaccta tgttggtgcc ttgtttaatg gtctgacact     1260

actgattttg gctctcattt cactcttcag tgttcctgtt atttatgaac ggcatcaggc     1320

acagatagat cattatctag gacttgcaaa taagaatgtt aaagatgcta tggctaaaat     1380

ccaagcaaaa atccctggat tgaagcgcaa agctgaatga aaacgcccaa aataattagt     1440

aggagttcat ctttaaaggg gatattcatt tgattatacg ggggagggtc agggaagaac     1500

gaaccttgac gttgcagtgc agtttcacag atcgttgtta gatctttatt tttagccatg     1560

cactgttgtg aggaaaaatt acctgtcttg actgccatgt gttcatcatc ttaagtattg     1620

taagctgcta tgtatggatt taaaccgtaa tcatatcttt ttcctatcta tctgaggcac     1680

tggtggaata aaaaacctgt atattttact ttgttgcaga tagtcttgcc gcatcttggc     1740

aagttgcaga gatggtggag ctagaaaaaa aaaaaaaaaa gcccttttca gtttgtgcac     1800

tgtgtatggt ccgtgtagat tgatgcagat tttctgaaat gaaatgtttg tttagacgag     1860

atcataccgg taaagcagga atgacaaagc ttgcttttct ggtatgttct aggtgtattg     1920

tgacttttac tgttatatta attgccaata taagtaaata tagattatat atgtatagtg     1980

tttcacaaag cttagacctt taccttccag ccaccccaca gtgcttgata tttcagagtc     2040

agtcattggt tatacatgtg tagttccaaa gcacataagc tagaagaaga aatatttcta     2100

ggagcactac catctgtttt caacatgaaa tgccacacac atagaactcc aacatcaatt     2160

tcattgcaca gactgactgt agttaatttt gtcacagaat ctatggactg aatctaatgc     2220

ttccaaaaat gttgtttgtt tgcaaatatc aaacattgtt atgcaagaaa ttattaatta     2280

caaaatgaag atttatacca ttgtggttta agctgtactg aactaaatct gtggaatgca     2340

ttgtgaactg taaaagcaaa gtatcaataa agcttataga cttaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaa                                                       2414


<210>  242
<211>  1808
<212>  DNA
<213>  homo sapiens

<400>  242
agcctagtta cagattgcac tgcgtcagac tgttccacac ccagaagacg tcaggtgact       60

tcagtcctgc tgcagttgtg cagcagagga gactgcagac ttcggttgag gaaacgggta      120

tttcatgtct cagggagtag gtttgtgcag ttacagcttt tctgttggta tgcataatta      180

ataattggag ctgcaaagca gatcgtgaca agagatggac ggtcagaaga aaaattggaa      240

ggacaaggtt gttgacctcc tgtactggag agacattaag aagactggag tggtgtttgg      300

tgccagccta ttcctgctgc tttcattgac agtattcagc attgtgagcg taacagccta      360

cattgccttg gccctgctct ctgtgaccat cagctttagg atatacaagg gtgtgatcca      420

agctatccag aaatcagatg aaggccaccc attcagggca tatctggaat ctgaagttgc      480

tatatctgag gagttggttc agaagtacag taattctgct cttggtcatg tgaactgcac      540

gataaaggaa ctcaggcgcc tcttcttagt tgatgattta gttgattctc tgaagtttgc      600

agtgttgatg tgggtattta cctatgttgg tgccttgttt aatggtctga cactactgat      660

tttggctctc atttcactct tcagtgttcc tgttatttat gaacggcatc aggcacagat      720

agatcattat ctaggacttg caaataagaa tgttaaagat gctatggcta aaatccaagc      780

aaaaatccct ggattgaagc gcaaagctga atgaaaacgc ccaaaataat tagtaggagt      840

tcatctttaa aggggatatt catttgatta tacgggggag ggtcagggaa gaacgaacct      900

tgacgttgca gtgcagtttc acagatcgtt gttagatctt tatttttagc catgcactgt      960

tgtgaggaaa aattacctgt cttgactgcc atgtgttcat catcttaagt attgtaagct     1020

gctatgtatg gatttaaacc gtaatcatat ctttttccta tctatctgag gcactggtgg     1080

aataaaaaac ctgtatattt tactttgttg cagatagtct tgccgcatct tggcaagttg     1140

cagagatggt ggagctagaa aaaaaaaaaa aaaagccctt ttcagtttgt gcactgtgta     1200

tggtccgtgt agattgatgc agattttctg aaatgaaatg tttgtttaga cgagatcata     1260

ccggtaaagc aggaatgaca aagcttgctt ttctggtatg ttctaggtgt attgtgactt     1320

ttactgttat attaattgcc aatataagta aatatagatt atatatgtat agtgtttcac     1380

aaagcttaga cctttacctt ccagccaccc cacagtgctt gatatttcag agtcagtcat     1440

tggttataca tgtgtagttc caaagcacat aagctagaag aagaaatatt tctaggagca     1500

ctaccatctg ttttcaacat gaaatgccac acacatagaa ctccaacatc aatttcattg     1560

cacagactga ctgtagttaa ttttgtcaca gaatctatgg actgaatcta atgcttccaa     1620

aaatgttgtt tgtttgcaaa tatcaaacat tgttatgcaa gaaattatta attacaaaat     1680

gaagatttat accattgtgg tttaagctgt actgaactaa atctgtggaa tgcattgtga     1740

actgtaaaag caaagtatca ataaagctta tagacttaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaa                                                              1808


<210>  243
<211>  2676
<212>  DNA
<213>  homo sapiens

<400>  243
agagccagcg gacggaacca ttccaaacag cctagtctcg tgctgagagc ctctccggtt       60

tcacgctgag acccgctcac ccccgctctg gccccttaga tgctattttg gcccgagtgt      120

cacgtcgggc gctctttaga gaggactggg acaagagttg cggacgcgaa gaacgagtaa      180

gcggtggttc atccctcctg accccacccc cgtggcctgg cccgatggtc gcgcccgggg      240

ttgcgagatt tgcgcctgcg cagtgcggcg cctagaggga aagcgagagg gagacggacg      300

ttgagagaac gaggaggaag gagagaaaat ggcgtccacg gattacagta cctatagcca      360

agctgcagcg cagcagggct acagtgctta caccgcccag cccactcaag gatatgcaca      420

gaccacccag gcatatgggc aacaaagcta tggaacctat ggacagccca ctgatgtcag      480

ctatacccag gctcagacca ctgcaaccta tgggcagacc gcctatgcaa cttcttatgg      540

acagcctccc actggttata ctactccaac tgccccccag gcatacagcc agcctgtcca      600

ggggtatggc actggtgctt atgataccac cactgctaca gtcaccacca cccaggcctc      660

ctatgcagct cagtctgcat atggcactca gcctgcttat ccagcctatg ggcagcagcc      720

agcagccact gcacctacaa gaccgcagga tggaaacaag cccactgaga ctagtcaacc      780

tcaatctagc acagggggtt acaaccagcc cagcctagga tatggacaga gtaactacag      840

ttatccccag gtacctggga gctaccccat gcagccagtc actgcacctc catcctaccc      900

tcctaccagc tattcctcta cacagccgac tagttatgat cagagcagtt actctcagca      960

gaacacctat gggcaaccga gcagctatgg acagcagagt agctatggtc aacaaagcag     1020

ctatgggcag cagcctccca ctagttaccc accccaaact ggatcctaca gccaagctcc     1080

aagtcaatat agccaacaga gcagcagcta cgggcagcag agttcattcc gacaggacca     1140

ccccagtagc atgggtgttt atgggcagga gtctggagga ttttccggac caggagagaa     1200

ccggagcatg agtggccctg ataaccgggg caggggaaga gggggatttg atcgtggagg     1260

catgagcaga ggtgggcggg gaggaggacg cggtggaatg ggcgctggag agcgaggtgg     1320

cttcaataag cctggtggac ccatggatga aggaccagat cttgatctag gcccacctgt     1380

agatccagat gaagactctg acaacagtgc aatttatgta caaggattaa atgacagtgt     1440

gactctagat gatctggcag acttctttaa gcagtgtggg gttgttaaga tgaacaagag     1500

aactgggcaa cccatgatcc acatctacct ggacaaggaa acaggaaagc ccaaaggcga     1560

tgccacagtg tcctatgaag acccacccac tgccaaggct gccgtggaat ggtttgatgg     1620

gaaagatttt caagggagca aacttaaagt ctcccttgct cggaagaagc ctccaatgaa     1680

cagtatgcgg ggtggtctgc caccccgtga gggcagaggc atgccaccac cactccgtgg     1740

aggtccagga ggcccaggag gtcctggggg acccatgggt cgcatgggag gccgtggagg     1800

agatagagga ggcttccctc caagaggacc ccggggttcc cgagggaacc cctctggagg     1860

aggaaacgtc cagcaccgag ctggagactg gcagtgtccc aatccgggtt gtggaaacca     1920

gaacttcgcc tggagaacag agtgcaacca gtgtaaggcc ccaaagcctg aaggcttcct     1980

cccgccaccc tttccgcccc cgggtggtga tcgtggcaga ggtggccctg gtggcatgcg     2040

gggaggaaga ggtggcctca tggatcgtgg tggtcccggt ggaatgttca gaggtggccg     2100

tggtggagac agaggtggct tccgtggtgg ccggggcatg gaccgaggtg gctttggtgg     2160

aggaagacga ggtggccctg gggggccccc tggacctttg atggaacaga tgggaggaag     2220

aagaggagga cgtggaggac ctggaaaaat ggataaaggc gagcaccgtc aggagcgcag     2280

agatcggccc tactagatgc agagaccccg cagagctgca ttgactacca gatttatttt     2340

ttaaaccaga aaatgtttta aatttataat tccatattta taatgttggc cacaacatta     2400

tgattattcc ttgtctgtac tttagtattt ttcaccattt gtgaagaaac attaaaacaa     2460

gttaaatggt agtgtgcgga gttttttttt cttccttctt ttaaaaatgg ttgtttaaga     2520

ctttaacaat gggaacccct tgtgagcatg ctcagtatca ttgtggagaa ccaagagggc     2580

ctcttaactg taacaatgtt catggttgtg atgttttttt ttttttttta aataaaattc     2640

caaatgttta taaagagtca aaaaaaaaaa aaaaaa                               2676


<210>  244
<211>  3027
<212>  DNA
<213>  homo sapiens

<400>  244
gggatatgta gtgcgtgact tccgcagtgc acgctgcgcc tgccgggcat tttttcctgg       60

tttgggggca aggtctcatg ggaaaggtca tgtctctcga agaaaggtta taaaccctga      120

gatatgaggg ttgggcgaga catccgagcc tgtttcgttc cgtgttggga ccaggaataa      180

ccctgacttc tgagctttca taaccccagg atcctccaga aaatttgcgg cgcgctgagg      240

gaaaaccttg ctgaagctgt acattggaat gcgtttacag tcattgtaat ggaagcaaaa      300

tacatgaagg aaaaactgtt atttgtatcc ctgcttattg cacctgacga ctagttgcag      360

atggttttgt ttacctaaga aaacttgtga tataaatgaa aaaaacacct gttttcctag      420

agtcattggt tacaaatatg cttcgtctaa gagctatttg tccattctcc tggagagtgt      480

ttcaatttcg acccatcagt tgtgaaccac taattattca gatgaataag tgtacagatg      540

aggagcaaat gtttggtttt attgaaagaa acaaagccat actttcagaa aagcaagtgg      600

gatgtgcatt tgatatgctt tggaagcttc aaaagcagaa gaccagcctg ttaaaaaatg      660

ctgagtatgt cagagaccat cctcaatttc ttactcttca taatttagct acaaataaat      720

tcaaattaat gaatgacgat accctggtga atgtgttata cgtcacacaa cagtttgctg      780

gtgaggccca tgacccgcta gttgaagcac tagttacaga agcatggaga aggctagaaa      840

ggtttgatat taaactgctc tcagaatttt cctcttgcct agcagatcag catttgtatt      900

ttagtccatt aatgggaaaa atagctgata ttgttcatag gaacttggaa accacacagg      960

acttaagttc cttgtctgtc ttgatggtca acatatcttc tttaatatca cgacattttc     1020

aacaacaact ggtgaacaaa acagaacttc tttttgacac catagattct tctgaggtca     1080

acgttgcaaa aagcatagca aagtttcttc gaaatgttag atatcgttat caaccactat     1140

tagaaagatg taataacgta tttttaagta atgtggacca ccttgatttg gattccatca     1200

gtaaaatact tagtgtatac aaatttctac aatttaatag ttttgaattt attataatgg     1260

ctaaaaagaa gctaactgaa atgattcctc tgtgtaatca tcctgctagc tttgtaaaat     1320

tgtttgtagc attgggaccc attgcaggac ctgaagaaaa gaaacaactt aaatcaacta     1380

tgttattgat gtcagaggac ctaactggcg agcaagccct ggcagtgttg ggagcaatgg     1440

gagatatgga aagcagaaac tcatgtctga ttaaaagagt tacttcagtt ctgcataaac     1500

atttggatgg ctataaacca ttagagttgt tgaagataac tcaagaatta acttttctgc     1560

atttccaaag gaaggagttt tttgcgaaac ttagagaatt actgcttagt tatttgaaaa     1620

atagtttcat accaactgag gtgtctgttc tggtccgtgc tatttccctg ctcccttctc     1680

ctcacttgga cgaagtgggg atatcccgaa ttgaagccgt tttaccacag tgtgacctaa     1740

ataacctgag tagttttgcc acatctgttt taagatggat tcagcatgat cacatgtatt     1800

tggataatat gactgcgaaa caactgaaac tacttcaaaa attagatcac tatggtcgtc     1860

agagactaca acacagcaac agtttggatc tgttacggaa ggaacttaaa tctctcaaag     1920

gaaacacgtt tcctgagtca cttcttgaag aaatgattgc tactttacag catttcatgg     1980

atgatattaa ttacataaat gttggggaga ttgcatcttt tatttctagt actgattacc     2040

tcagtacttt gctactagat aggatagcct cagtggctgt tcagcagatt gaaaagatcc     2100

atccttttac aatccctgct attattcgtc cattcagcgt attgaactat gatccacctc     2160

aaagggatga atttttggga acttgcgtgc aacatcttaa ttcttactta ggtatattgg     2220

atccttttat attagtgttt cttggtttct ctttggccac acttgaatat tttccagaag     2280

atctgctaaa ggcaattttt aacatcaaat tcttagctag attggattct caacttgaaa     2340

ttttatctcc atctcgaagt gcaagagtcc agtttcatct tatggagtta aatagatcag     2400

tctgcttgga atgccctgag tttcagattc catggtttca tgaccgcttc tgtcaacaat     2460

ataataaagg tattggtggc atggatggaa cacaacagca gatttttaaa atgttagcag     2520

aggtactagg aggaatcaat tgtgtaaaag cctcggttct tacgccttat taccacaaag     2580

tagattttga gtgtatcttg gataaaagaa aaaaacctct tccgtatgga agccataata     2640

tagcattggg acaactacca gaaatgccct gggaatcaaa tatcgaaata gttggatcaa     2700

ggctgccacc aggggctgaa aggattgctt tggaattttt ggattcaaaa gcactttgta     2760

gaaatatccc tcacatgaaa ggaaaatctg ctatgaaaaa acgacatttg gaaattctgg     2820

ggtatcgtgt aattcagatt tcccagtttg aatggaactc tatggcactg tcaacaaagg     2880

atgctcggat ggactacctg agagaatgta tatttggaga agtcaagtca tgtttgtagt     2940

ttttatttaa aatgaatgtt atcgtgtgtt acatttggac ctattttaat aaagtggcct     3000

gtctcaatta aaaaaaaaaa aaaaaaa                                         3027


<210>  245
<211>  1999
<212>  DNA
<213>  homo sapiens

<400>  245
ccggagcccc gccagagccc gacttcagcc ccagccagat cccgcgtcaa cggaggcgga       60

acggcggacc ccgtaccctg gcagcatcgg agcaccggcg ggtgaaggca aggtccctgg      120

actggtcata tacctcttgt ggccctggca gaatcaagat gaggccctgt catgcctccc      180

cagtgaggcc tacagtctga gcagacagca tggcctgcca ctggcagtga acaccatgtc      240

tgcaggaggt ggccgggcct ttgcttggca agtgttcccc cccatgccca cttgccgggt      300

ctatggcaca gtggcacacc aagatgggca cctgctggtg ttggggggtt gtggccgggc      360

tggactgccc ctggacactg ctgagacact ggacatggcc tcgcacacat ggctggcact      420

ggcacccctg cccactgccc gggctggtgc agctgcggta gttctgggca agcaggtgct      480

agtggtgggt ggtgtggatg aggtccagag cccggtagct gctgtagagg ccttcctgat      540

ggatgagggc cgctgggagc gtcgggccac cctccctcaa gcagccatgg gggttgcaac      600

tgtggagaga gatggtatgg tgtatgctct ggggggaatg ggccctgaca cggcccccca      660

ggcccaggta cgtgtgtatg agccccgtcg ggactgctgg ctttcgctac cctccatgcc      720

cacaccctgc tatggggcct ccaccttcct gcacgggaac aagatctatg tcctgggggg      780

ccgccagggc aagctcccgg tgactgcttt tgaagccttt gatctggagg cccgtacatg      840

gacccggcat ccaagcctac ccagccgtcg ggcctttgct ggctgcgcca tggctgaagg      900

cagcgtcttt agcctgggtg gcctgcagca gcctgggccc cacaacttct actctcgccc      960

acactttgtc aacactgtgg agatgtttga cctggagcat gggtcctgga ccaaattgcc     1020

ccgcagcctg cgcatgaggg ataagagggc agactttgtg gttgggtccc ttgggggcca     1080

cattgtggcc attgggggcc ttggaaacca gccatgtcct ttgggctctg tggagagctt     1140

tagccttgca cggcggcgct gggaggcatt gcctgccatg cccactgccc gctgctcctg     1200

ctctagtctg caggctgggc cccggctgtt tgttattggg ggtgtggccc agggccccag     1260

tcaagccgtg gaggcactgt gtctgcgtga tggggtctga aggcttggtg ggagctgtcc     1320

actggagcag ctcattgcca gaggcagcta tttctatggc tccttttgct gctgaggaca     1380

ctcactgtgg ctctgtggga tgagagaggc atgggggtga gcacttgaaa cactgccttg     1440

gggccttggg ttaggggagc ctttgtcttt agtgcaggac acacatatgc ttacacctac     1500

ctttatcacc attcgttcat gaatcatgcc tagctccatc cttgccctgg gacctactag     1560

gccttccatc caactgggaa atggggagaa gcaaagctgg cctcatgctc ttcagggtca     1620

gttcctatct ggagttgacc aggcctaccc cagttgccat tcctgaaaaa tctcagctgc     1680

caggctgcct ttagggtccc tgcagaccca ggagagttga gagggtgggg gacacagaga     1740

gaatagagag gatgtgggaa ctgccagagg gccggagcgc aggagttcaa gtggaggaat     1800

gctggctttg agccctctac actgctggtt gtatgacctt ggacaagtca cttcacctct     1860

ctgtgcctca gcatcctcat ctataaatgg ggatctctga aaccttccta ccctacctac     1920

ctcacagggc tgttgtgagg acccagggag tttggatgtg gaagtaaaag tgctgctaaa     1980

acctaaaaaa aaaaaaaaa                                                  1999


<210>  246
<211>  6874
<212>  DNA
<213>  homo sapiens

<400>  246
agctgcaagt tgggctgcag gggcagcgca tacactacaa tggctgctgg aaagaggcgt       60

aaggaaacaa tttccaggcc cgccgcgtcc agcccgaaat atgagaaaaa aattattaga      120

aattccgcgg gcggtgtaga ggcggcggac gggccggagg gaggatgtta aagccccgcg      180

attggccaaa atgggaagga ttggattcca ctctcttcca cgaagagtca atgggactgg      240

ctaagatcaa agtctgaggc tttttccatc agtaatcagg cacatggcta ctcattctcc      300

tgagaaaacc cacaagtgta attattgtga gaaaatgttt caccggaaag atcatctgaa      360

gaatcacctc catacacacg accctaacaa agagacgttt aagtgcgaag aatgtggcaa      420

gaactacaat accaagcttg gatttaaacg tcacttggcc ttgcatgccg caacaagtgg      480

tgacctcacc tgtaaggtat gtttgcaaac ttttgaaagc acgggagtgc ttctggagca      540

ccttaaatct catgcaggca agtcgtctgg tggggttaaa gaaaaaaagc accagtgcga      600

acattgtgat cgccggttct acacccgaaa ggatgtccgg agacacatgg tggtgcacac      660

tggaagaaag gacttcctct gtcagtattg tgcacagaga tttgggcgaa aggatcacct      720

gactcgacat atgaagaaga gtcacaatca agagcttctg aaggtcaaaa cagaaccagt      780

ggatttcctt gacccattta cctgcaatgt gtctgtgcct ataaaagacg agctccttcc      840

ggtgatgtcc ttaccttcca gtgaactgtt atcaaagcca ttcacaaaca ctttgcagtt      900

aaacctctac aacactccat ttcagtccat gcagagctcg ggatctgccc accaaatgat      960

cacaacttta cctttgggaa tgacatgccc aatagatatg gacactgttc atccctctca     1020

ccacctttct ttcaaatatc cgttcagttc tacctcatat gcaatttcta ttcctgaaaa     1080

agaacagcca ttaaaggggg aaattgagag ttacctgatg gagttacaag gtggcgtgcc     1140

ctcttcatcc caagattctc aagcatcgtc atcatctaag ctagggttgg atcctcagat     1200

tgggtcccta gatgatggtg caggagacct ctccctatcc aaaagctcta tctccatcag     1260

tgacccccta aacacaccag cattggattt ttctcagttg tttaatttca tacctttaaa     1320

tggtcctccc tataatcctc tatcagtggg gagccttgga atgagctatt cccaggaaga     1380

agcacattct tctgtttccc agctcccccc acaaacacag gatcttcagg atcctgcaaa     1440

cactataggg cttgggtctc tgcactcact gtcagcagct ttcaccagca gtttaagcac     1500

aagtaccacc ctcccacgtt tccatcaagc ttttcagtag gattctggga catggattca     1560

ttacagaaat gtatgtgtag ctgtgcccta gatgaccatt tttattttag tgcctacttt     1620

aaaacagtat aaaaatttct gcttttgtat aatacaaatt ttcattaagc cagtataaaa     1680

tagaaactag cttttaaact gagctttgga accatttgtg ttcagttaag tttacctggg     1740

tattttgtcc tgattcactg ccaattgtca cattttaaga cttttttttt tccatatagg     1800

aaagccatta ttagtagtaa acttttacaa atcccatttt caaattactt ttagatctta     1860

aaattttcat ttttgtctaa taacagtggc tctacctttt gacatctggc tcattaaaaa     1920

atttagcaat agaatgtaaa ttgtataaaa agtttgtgaa taactcaagg gtttaaattt     1980

tcttactagc ttctaaatgg attaataatc aagtgcttca aatgaattaa gagtccagtt     2040

tcggaagata ataaatgttt gttagataca ccataatttc agatcagtat attctgaaga     2100

ctccctgttg tctggctaaa atatttgcca tctttattat gagcctttaa ggaaaacaaa     2160

ccctaaacac aaagcatcag tatttatagc aaaaagagac tctgttaggt gacatggcat     2220

ttcgtgtcac ttaatagttg gccctaaatt agtacacagg atattttgtc gtgtttcatc     2280

cttcttaaca tgctatcttt tcatttaata atagtaatag tgtatggcat tggggtcttc     2340

agagtcgata tataggtaga tctctttagt cttttccacc tttcacatcc aaggggtggg     2400

tcaagtgcag ccagcaattt attttcattg ttggcccacg gttagtccat aatctagagc     2460

cattgtggaa ctgcagccat gaggtgtgtt tatcccacag tggattgact cagcctctgt     2520

gggtgacaga cttctaagca ggaagataga cgtgaagcac atggttacat ttgggaactt     2580

gtgtagggat catggcccct gtagccaggg ttaaaaactg gactttttag aagtaaagta     2640

aaagcatatc gcttatatca tttcttgctg aatttgatat gtttttcttt cccttaagaa     2700

tcaaaagcag aaaacaaaaa caacagtcct actccgatgt tatctttctg attcaatgtg     2760

aatccatctt tccttgcaat attttggatg gagaatttga agttaaatgc attagaaaac     2820

tacctgatga actaccacaa agttttaagt gactagaaat atatacagta aaatcccact     2880

ttcatgcatc tctgggaaat gataggagta ttgcaaataa gttgagtttg tagagggtaa     2940

caaagtaaag taaaacaaac ctatcttggt taacatgaaa ataacaattg agaatatatt     3000

atattcactg aataattata ggcttttcct cacattagac aaccaacata atcttcttaa     3060

aggtctaatt aatatatttt tctaagggtc agttgggaca ttaacctaag aaacatatct     3120

attaagcact tgttaacacc ttattttagg accctttccg ttggggatgg gggcaagggt     3180

gggaggtttt tagaagagta tatatctctt taaaaaaaaa cagaaagaaa aatatttctg     3240

agcactcatt agccctatat ggaaacttct ttcctttttg tagggccagt tatcactgca     3300

gattgcaatg tttaccaaga atttctaaaa atgagtgcag attactgaat ataatacatt     3360

atttaaaata tttgggagta gtataatttg tggagaaatg taaattgtaa taatgtaaat     3420

gggggcttca atatatatat ataatacaca cacacacaca catgcacaca taccgcactt     3480

catagaatca aagttgctct ctgaaggagc tttggctcct gatattttat catgctccta     3540

tattttttta atccttggag cagtagtttt tatacttatg tatttaaatt ttattatgaa     3600

aaattacatt tattaaaaaa gtgtgttcca aaggcattaa aattatatat gttaataagg     3660

aagtacattt ttaaattttt caaactgctc ctagcttttg attaggagaa tattttttct     3720

gaaagtaggc ttttcgctct gcttcattac tgcttccttt agtttctatg aaacagattg     3780

cttacctaaa tctttagttg aatgattagt gttcaatatt gctttaatca ccatataaaa     3840

ggaaaaaaat tggtgacaga gcacaaatag aaaacctatt tttaaataga aatcacaaat     3900

agcaagtgtg gaagcactac tttattctgt ttaaaatgta cttaagaagt catcaaatta     3960

gtgaactgag acattggcct tagtaggctg tattcactgc taatttaaaa aagggagtac     4020

caggatttat taagtaaagc attttggaaa tggggaatag cgccatatat gtatgtatgt     4080

gtatgtgtgt gtgtgtgtgt gtatatatac acacacacac acatacttaa atcttgccct     4140

gcatgaaatt caaatacatg gaggcacatc ttcagggcac cagtgttaaa attttggagt     4200

cttaattttc atgtgtacac ctctttgcct gttcccaccc ccagacttga aataacactt     4260

cagagtaaga gggaattcag ctaatttgtt tttaaaattg actgtagtgg tcactaaacc     4320

ctttttgaga gaatttctat taaagatgag gcagactcgc ttatttgaat tgcacaatgt     4380

tctaacaagg atgtaacaca gaattggctt ttttttccct agaaaaagat tgtttgtttc     4440

tatgtcaact agatatgatt aaaaataagt attgccaatg ctgttttcat tctctagtgg     4500

ccagaatcat tatccttgaa atttctggta gtgccttagc ttggttaaaa aaaaaaaaaa     4560

aaaaaaaaaa aagggattaa cattaaataa aagtagttta gaatttgggc ctcagacaag     4620

atattgaacc tcattcagtt tcacttccac atgtatgtac aagttaggtc accaaacacg     4680

gaagtgtgag tgtggaagga tcttggcact gtaagcaatg ctatccattg atgtatacaa     4740

gtacctttat agttatcgat cactgttaaa actttcattt taaaatccta ttaccaagtt     4800

cagtttttta aaacttcaat tgtcctggct gattatgcat cactctgtgt gcaacttttt     4860

tatttcattt agtgtttctt tcaagctgtg tatttttgcc tatttgttgc ttgtgcttta     4920

tttttcttag tcatttgtgg aatatagtga tatattgtgt taatttggac agtagcggtt     4980

tttaaaaacc atatactgac tgaaacatga gccagagccg attgctttat taagctaata     5040

atgaatgtta aagagtacat attttcagga tcgttcatct agtgagcaat acacatatta     5100

taggccaata tttttttaaa aaatagagct tggtcaacct ctatactaca catattacaa     5160

gatatagcac tttcaaaatg aatctaaacc tttacagaaa ctttcttata ggttatgcct     5220

tttattttaa gacttattat aattcaagtg ccattagatg atatatatgt aggcctttga     5280

tatataatgc tttgtgtaca aaaatggtag atggtatttt aaacaggtac atttttacag     5340

tgttttctta tcaatttgct atattgcaca gaatcagtgt gtgtcttttc ataaggtttt     5400

acaatggttt atttttttac aaggtttacg tgtctcaaag cacactgtct tcccagtacg     5460

taagttaaaa aataccagtt cacccaagtt gcttctagcc tactgagatc catgtgacat     5520

tggaggagat cttttaaatg tttagtattc gtcattagca atggctggct gttagttctg     5580

gtaaatgtgt gcctaagttg aatttgtctt gtttttctca cactgtgtca gcagccatgt     5640

ctacaacaca gataagtctg ttgtgatcac atagatctac ataagttgtg cagttttgtg     5700

ctaaaaaccc atagggagct cctttgggat catagaaaag aagatcatgc aaccagcatt     5760

ggtgaaggca cactcagatt gcacttaggg cctttctatg atgttgtcaa ccctctgagg     5820

atggaaggca gtgtcttttg atgttatcta gcctagaaat gacacagaac tattgctaat     5880

gtataaaaca cttcattata taagcttcag tggtacagat gaaccagaat gaatgtttat     5940

cttctcagaa acactccttc aatattatat tggatcatgc tgctaatgta acttgggcta     6000

caactcttca tggtgctaca aacttctctg tctcattcag tcgtattttt ttatccatag     6060

aaaaaggact acattaggtg taaaagtgta caatatattt ttatactgtg acttaatttg     6120

tcattaacaa acttttacac caccacaatg tattcatgtg cacttgcaaa aggagatctc     6180

ggacatgcaa atgttaccag aacaaaccca gcttttgtcc acaaggtgac tgtaactcag     6240

aatggaaagt gggctttata atagggtgtg gagtgaagaa catgctgtat gttactaaca     6300

gccctttgaa tttaacaaaa actgggaatc cattaggaaa cggattgcat catacctgaa     6360

cataagctgg actgctgaaa ttgtattttt agctaatgaa aaagtgtttg gactagtact     6420

ctaaaaatgt tctaatgata aagttttgag tcaaaataga aaagaaaaaa atctgcattc     6480

caggccgaat tttgtatatt tttattgcat ttaaaattgc tattctgtaa tattgggaaa     6540

tcaagtggct tatcatgtat atcgtgtact taaaatgtat tcacaaacta ctgttgtatt     6600

tgtataaaat atagacaaag atcatatttt ttgtgtgtgt ataagctctg taaaatagca     6660

atcacattat gaagctgcag tgatactaca ttttaaacat tcacatccaa agaagcagac     6720

tatttattgt ccatatacca gatttaaaat attaatttgc tgctaattaa ataatagtac     6780

tgcagcttct tgtggcctac agtgttatgt ttgctgtaag aataagatat gtgaattcca     6840

caaaatatat gaataaaatt atagaatggc ttta                                 6874


<210>  247
<211>  7103
<212>  DNA
<213>  homo sapiens

<400>  247
cactcgctct ctccctctgt gtatagagga tgtgctgaat ggtgcgcttt gaggcggcgg       60

cggcggagga gcagaatccg ccgcgactgg cagcctcggc tgaccggctc ggcttctctt      120

cgccttccga ggctcctcat ccaccgcggg ctccagacct cgcgtcccgc ccggggcatg      180

gccgggcgct gcgcccccgc gcgctctgcc tgctgagcgg cgccggaggg aggtgcggag      240

gccgggaggc cggggaggcc ggcggggagc agagtcgagc gcctccggag cagagaaagg      300

agcccgcgcc ccgcgccccg cgccccgcgc acggtcccca gtccctgccg cgctcgcccg      360

ggccgcccgg agcccagatg agcccagatg gccggggctc aacccggagt gcacgccttg      420

caactcaagc ccgtgtgcgt gtccgacagc ctcaagaagg gcaccaaatt cgtcaagtgg      480

gatgatgact caactattgt tactccaatt attttgagga ctgaccctca gggatttttc      540

ttttactgga cagatcaaaa caaggagaca gagctactgg atctcagcct tgtcaaagat      600

gccagatgtg ggagacacgc caaagctccc aaggacccca aattacgtga acttttggat      660

gtggggaaca tcgggcgcct ggagcagcgc atgatcacag tggtgtatgg gcctgacctc      720

gtgaacatct cccatttgaa tctcgtggct ttccaagaag aagtggccaa ggaatggaca      780

aatgaggttt tcagtttggc aacaaacctg ctggcccaaa acatgtccag ggatgcattt      840

ctggaaaaag cctatactaa acttaagctg caagtcactc cagaagggcg tattcctctc      900

aaaaacatat atcgcttgtt ttcagcagat cggaagcgag ttgaaactgc tttagaggct      960

tgtagtcttc catcttcaag gaatgattca atacctcaag aagatttcac tccagaagtg     1020

tacagagttt tcctcaacaa cctttgccct cgacctgaaa ttgataacat cttttcagaa     1080

tttggtgcaa aaagcaaacc atatcttacc gttgatcaga tgatggattt tatcaacctt     1140

aagcagcgag atcctcggct taatgaaata ctttatccac ctctaaaaca agagcaagtc     1200

caagtattga ttgagaagta tgaacccaac aacagcctcg ccagaaaagg acaaatatca     1260

gtggatgggt tcatgcgcta tctgagtgga gaagaaaacg gagtcgtttc acctgagaaa     1320

ctggatttga atgaagacat gtctcagccc ctttctcact atttcattaa ttcctcgcac     1380

aacacctacc tcacagctgg ccaactggct ggaaactcct ctgttgagat gtatcgccaa     1440

gtgctcctgt ctggttgtcg ctgtgtggag ctggactgct ggaagggacg gactgcagaa     1500

gaggaacctg tcatcaccca tggcttcacc atgacaactg aaatatcttt caaggaagtg     1560

atagaagcaa ttgcggagtg tgcatttaag acttcacctt ttccaattct cctttcgttt     1620

gagaaccatg tggattcccc aaagcagcaa gccaagatgg cggagtactg ccgactgatc     1680

tttggggatg cccttctcat ggagcccctg gaaaaatatc cactggaatc tggagttcct     1740

cttccaagcc ctatggattt aatgtataaa attttggtga aaaataagaa gaaatcacac     1800

aagtcatcag aaggaagcgg caaaaagaag ctctcagaac aagcctccaa cacctacagt     1860

gactcctcca gcatgttcga gccctcatcc ccaggagccg gagaagctga tacggaaagt     1920

gacgacgacg atgatgatga tgactgtaaa aaatcttcaa tggatgaggg gactgctgga     1980

agtgaggcta tggccacaga agaaatgtct aatctggtga actatattca gccagtcaag     2040

tttgagtcat ttgaaatttc aaaaaaaaga aataaaagtt ttgaaatgtc ttccttcgtg     2100

gaaaccaaag gacttgaaca actcaccaag tctccagtgg aatttgtaga atataacaaa     2160

atgcagctta gcaggatata tccaaaagga acacgtgtgg attcatccaa ctatatgcct     2220

cagctcttct ggaatgcagg ttgtcagatg gtggcactta atttccagac aatggacctg     2280

gctatgcaaa taaatatggg gatgtatgaa tacaacggga agagtggcta cagattgaag     2340

ccagagttca tgaggaggcc tgacaagcat tttgatccat ttactgaagg catcgtagat     2400

gggatagtgg caaacacttt gtctgttaag attatttcag gtcagtttct ttctgataag     2460

aaagttggga cttacgtgga agtagatatg tttggtttgc ctgtggatac aaggaggaag     2520

gcatttaaga ccaaaacatc ccaaggaaat gctgtgaatc ctgtctggga agaagaacct     2580

attgtgttca aaaaggtggt tcttcctact ctggcctgtt tgagaatagc agtttatgaa     2640

gaaggaggta aattcattgg ccaccgtatc ttgccagtgc aagccattcg gccaggctat     2700

cactatatct gtctaaggaa tgaaaggaac cagcctctga cgctgcctgc tgtctttgtc     2760

tacatagaag tgaaagacta tgtgccagac acatatgcag atgtcatcga agctttatca     2820

aacccaatcc gatatgtgaa cctgatggaa cagagagcta agcaattggc tgctttgaca     2880

ctggaagatg aagaagaagt aaagaaagag gctgatcctg gagaaacacc atcagaggct     2940

ccaagtgaag cgagaacgac tccagcagaa aatggggtga atcacactac aaccctgaca     3000

cccaagccac cctcccaggc tctccacagc cagccagctc caggttctgt aaaggcacct     3060

gccaaaacag aagatcttat tcagagtgtc ttaacagaag tggaagcaca gaccatcgaa     3120

gaactaaagc aacagaaatc gtttgtgaaa cttcaaaaga aacactacaa agaaatgaaa     3180

gacctggtta agagacacca caagaaaacc actgacctta tcaaagaaca cactaccaag     3240

tataatgaaa ttcagaatga ctacttgaga aggagagccg ctttggaaaa gtccgccaaa     3300

aaggacagta agaaaaaatc ggaacccagc agccctgatc atggttcatc aacgattgag     3360

caagacctcg ctgctctgga tgctgaaatg acccaaaagt taatagactt gaaggacaaa     3420

caacagcagc agctgcttaa tcttcggcaa gaacagtatt atagtgaaaa ataccagaag     3480

cgagaacata ttaaactgct tattcaaaag ttgacggatg tcgcagaaga gtgtcagaac     3540

aatcagttaa agaagctcaa agaaatctgt gagaaagaaa agaaagaatt aaagaagaaa     3600

atggataaaa agaggcagga gaagataaca gaagctaaat ccaaagacaa aagtcagatg     3660

gaagaggaga agacagagat gatccggtca tatatccagg aagtggtgca gtatatcaag     3720

aggctagaag aagcgcaaag taaacggcaa gaaaaactcg tagagaaaca caaggaaata     3780

cgtcagcaga tcctggatga aaagcccaag ctgcaggtgg agctggagca agaataccaa     3840

gacaaattca aaagactgcc cctcgagatt ttggaattcg tgcaggaagc catgaaagga     3900

aagatcagtg aagacagcaa tcacggttct gcccctctct ccctgtcctc agaccctgga     3960

aaagtgaacc acaagactcc ctccagtgag gagctgggag gagacatccc aggaaaagaa     4020

tttgatactc ctctgtgaat gctcctgcca ggccttcaga aattgcatgg ccactccagc     4080

gtcatcggac tctctcttat tacaaagatc actgcccagg accatcttcc cgagaagcat     4140

cccttagcct aaaatccaca ccaaagggag agttccagag gaatccatga agaattccca     4200

tgcccaggct ccatgtgtca tgtggaaacc tccacaggtc tgctagtgaa gaatgcatgt     4260

atgtgagatt tttgttttct ttccaatagc aaattcaaag caagcaactt gcaggctcca     4320

tggaactttt aatgaaggac agtgtcttct ttgaagaaaa tcaagctcgt gtttttattc     4380

gaagctctgg tgtaaaatat ttcaaagtca tagaaatagt ttgagaaatg catagcatta     4440

tttaacacta ttgaacagcc gactttgagc attgtttctt ctaactgccc ctcaactacc     4500

attatcttca agtcaacatg catattacat tttcatcctt tgctttgcaa gcactggtgg     4560

cttgcagttt gctaatttat ttatcataga gtcatcaatg tatttgttgc tgacatggtt     4620

ttattagata ctgtagtgat tcaaataagt tttctatttg aaaaaaaaaa tcacttgatt     4680

gtatccttgc ccagtgaagc catcctaaga cttagcaata tggattgtac atttggctgc     4740

atgagcaagt cggccgcaca cttccagaca gtgtgctgtt tgaattgact atttgcactc     4800

aaagtctggg tattcattgg ttattggcct gaaatgatca aataactaca aatgatctgt     4860

tgaataaaaa tagttgagct gatatatgtt aagcagatat tcaatcagaa tgaacaggtt     4920

ccggtggtta ttttgccgtt tgacattttt tatggttcat ttatttttaa tatagagagg     4980

aagattgaat atttatctag agaatacaaa gacccacatg taaatgatag gtattatctc     5040

catgtatata tgtacccact tagtcatgta agtgcatata cacatacaca cacatgagtg     5100

tagacatgtg tttattaatt gacaatgacc caaatctctt ccacaagact taaaaccaaa     5160

ttcagggaca aatggataga gaagaaaagg gtcaaacatc gagattacat ggatgttaaa     5220

ttatatggag acgctaagaa ataattgatg gagccattga tgcaaaccga agtagattta     5280

gaacttatat gaatttgatt tatattttgc aagatcaaaa attagatgtt aagtatcaga     5340

ttttaagctt gttttaatgg tcaaaaaatt aggacagaaa taatatggac atttattagt     5400

atcttccata atttttaagt ctgacacatt tctattttat tctaacataa aaaaacttcc     5460

attatatatt tactaagtat atttaattca cttaactctg tctttataag ttcctatttt     5520

agatggaata agagaaacaa attatatcaa ggtaaaactg atcaaaagca taattgaaag     5580

ttctgaaaaa agaaaaataa taatatgtag aaaaatgtaa cttagagagt aacacatgaa     5640

cattgaagtt aaaacccaga agccagatgc tcacagtttt attttacttt aaaataaacc     5700

tgtctgactg tagctttgtg aaatatctta aaacgcaaaa accaattgtg tcctgaaaat     5760

tgtttcaaga atttaatatt tttatgaaaa ttattttatt taactttaag caataactag     5820

agattacaat taaattttaa tcaaaatgaa ggcttagttc aaacataagg aaacagtgtt     5880

tgattaaaaa aaacacatct agtaagacgt aaggggaaaa tcacatcctc tttggagatg     5940

attatatttt gatctgaagg gtttggggtg ttcattagac acttaataaa acttaacttc     6000

caatgaaaaa gaaatctttt gtaaatcatt ctacttttgc actttgaaag aaaggcgtta     6060

atcataaaga agcaagaatg gtcaaaatcg aatgctgcat ttttataaac aaaattacag     6120

actgtctgaa attgaagaag aatgaactaa taatagcatt cataaccaaa cacaatgatg     6180

attattgcag aacattgtat cacattttag tccagagata gaataaagtt gaataacctt     6240

gacttacaca aaactgtttt ggtagttgga tttcattatc ttagtgaatt tagtcatttt     6300

acaatatgtt tgtatttggc catttactgt aatcacattt ttatatctgt acaatgacac     6360

tttttgcagt tgtggggtag tgtgtaacac tgtccatctt gcatcattga aactactaca     6420

atgatactat catttaataa tattaatatt acttgaaata gactaagata aagaaaaggg     6480

gtctgtatga tgtgcagttt tgtgccttta tgtatttgcc ttgttctttg tcgaatgtgt     6540

gaaattccgt actgtggttt ttcctataat agaaagtaga gctgtgtatt aaattagact     6600

gtgtctctct gataccttta cactactgag aatagcatgg ttttggccat gtaaaccaat     6660

tttcaaagtt ctaatgacat agccatgtgt ttttggtttt ttatatttca ttttaaaatt     6720

tgagtatcac catacattaa ttaatactcc tgtagtagat aagctgtcat taagtaattc     6780

ccaaaaaaag ggccatttgc ttgcattact ttgaatttaa tgttgcgctt gtgcactgtg     6840

ttaatattgt ttgtgatgga ttggacgttg tgactcttgc cttttaagaa gaaaaaaaag     6900

ataggacaaa gtatttgaag ctcttaaaat gtacatattt tggttcttct atctcaaatt     6960

atttaaaatg cataattcac atttttgtaa taattctatg caattttgtg gcatgatgtt     7020

tcttccactt gtaattttat gtgctttcat cacaaatcca aaggaaagaa taaaaatttc     7080

ttaacacaaa aaaaaaaaaa aaa                                             7103


<210>  248
<211>  1687
<212>  DNA
<213>  homo sapiens

<400>  248
gattgtggga aggcagctga actcggcgcc tggaaagatg gaggcagcgg agacagaggc       60

ggaagctgca gccctagagg tcctggctga ggtggcaggc atcttggaac ctgtaggcct      120

gcaggaggag gcagaactgc cagccaagat cctggttgag tttgtggtgg actctcagaa      180

gaaagacaag ctgctctgca gccagcttca ggtagcggat ttcctgcaga acatcctggc      240

tcaggaggac actgctaagg gtctcgaccc cttggcttct gaagacacga gccgacagaa      300

ggcaattgca gctaaggaac aatggaaaga gctgaaggcc acctacaggg agcacgtaga      360

ggccatcaaa attggcctca ccaaggccct gactcagatg gaggaagccc agaggaaacg      420

gacacaactc cgggaagcct ttgagcagct ccaggccaag aaacaaatgg ccatggagaa      480

acgcagagca gtccagaacc agtggcagct acaacaggag aagcatctgc agcatctggc      540

ggaggtttct gcagaggtga gggagcgtaa gacagggact cagcaggagc ttgacagggt      600

gtttcagaaa cttggaaacc tgaagcagca ggcagaacag gagcgggaca agctgcagag      660

gtatcagacc ttcctccagc ttctgtatac cctgcagggt aagctgttgt tccctgaggc      720

tgaggctgag gcagagaatc ttccagatga taaaccccag cagccgactc gaccccagga      780

gcagagtaca ggagacacca tggggagaga ccctggtgtg tccttcaagg ctgttggtct      840

acaacctgct ggagatgtaa atttgccatg acttcctgga ggacagcagc atggagaaag      900

atcctagaaa aggcctctga cttccctcac ctcccaacca tcattacagg aaagactgtg      960

aactcctgag ttcagcttga tttctgacta catcccagca agctctggca tctgtggatt     1020

aaaatccctg gatctctctc agttgtgtat ttgttcatct tcatatgctg gcaggaacaa     1080

ctattaatac agatactcag aagccaataa catgacagga gctgggactg gtttgaacac     1140

agggtgtgca gatggggagg gggtactggc cttgggcctc ctatgatgca gacatggtga     1200

atttaattca aggaggagga gaatgtttta ggcaggtggt tatatgtggg aagataattt     1260

tattcatgga tccaaatgtt tgttgagtcc tttctttgtg ctaaggttct tgcggtgaac     1320

cagaattata acagtgagct catctgactg ttttaggatg tacagcctag tgttaacatt     1380

cttggtatct ttttgtgcct tatctaaaac atttctcgat cactggtttc agatgttcat     1440

ttattatatt cttttcaaag attcagagat tggcttttgt catccactat tgtatgtttt     1500

gtttcattga cctctagtga taccttgatc tttcccactt tctgttttcg gattggagaa     1560

gatgtacctt ttttgtcaac tcttactttt atcagatgat caactcacgt atttggatct     1620

ttatttgttt tctcaaataa atatttaagg ttatacattt aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaa                                                               1687


<210>  249
<211>  2447
<212>  DNA
<213>  homo sapiens

<400>  249
ggggcggggc tggcggcgcc ggcgcagccc gggggcggcg ggaggaggag gtggcggcgg       60

tggcgctggg agctcctgtc accgctgggg ccgggccggg cgggagtgca ggggacgtga      120

gggcgcaagg gccgggacat ggggcccgcc agccccgctg ctcgcggtct aagtcgccgc      180

ccgggccagc cgccgctgcc gctgctgctg ccactattgc tgctgcttct gcgcgcgcag      240

cccgccatcg ggagcctggc cggtgggagc cccggcgcgg ccgaggcccc ggggtcggcc      300

caggtggctg gactatgcgg gcgcctaacc cttcaccggg acctgcgcac cggccgctgg      360

gaaccagacc cacagcgctc tcgacgctgt ctccgggacc cgcagcgcgt gctggagtac      420

tgcagacaga tgtacccgga gctgcagatt gcacgtgtgg agcaggctac gcaggccatc      480

cccatggagc gctggtgcgg gggttcccgg agcggcagct gcgcccaccc ccaccaccag      540

gttgtgccct tccgctgcct gcctggtgaa tttgtgagtg aggccctgct ggtgcctgaa      600

ggctgccggt tcttgcacca ggagcgcatg gaccaatgtg agagttcaac ccggaggcat      660

caggaggcac aggaggcctg cagctcccag ggcctcatcc tgcacggctc gggcatgctc      720

ttaccctgtg gctcggatcg gttccgtggt gtggagtatg tgtgctgtcc ccctccaggg      780

acccccgacc catctgggac agcagttggt gacccctcca cccggtcctg gcccccgggg      840

agcagagtag agggggctga ggacgaggaa gaggaggaat ccttcccaca gccagtagat      900

gattacttcg tggagcctcc gcaggctgaa gaggaagagg aaacggtccc acccccaagc      960

tcccatacac ttgcagtggt cggcaaagtc actcccaccc cgaggcccac agacggtgtg     1020

gatatttact ttggcatgcc tggggaaatc agtgagcacg aggggttcct gagggccaag     1080

atggacctgg aggagcgtag gatgcgccag attaatgagg tgatgcgtga atgggccatg     1140

gcagacaacc agtccaagaa cctgcctaaa gccgacagac aggccctgaa tgagcacttc     1200

cagtccattc tgcagactct ggaggagcag gtgtctggtg agcgacagcg cctggtggaa     1260

acccacgcca cccgcgtcat cgcccttatc aacgaccagc gccgggctgc cttggagggc     1320

ttcctggcag ccctgcaggc agatccgcct caggcggagc gtgtcctgtt ggccctgcgg     1380

cgctacctgc gtgcggagca gaaggaacag aggcacacgc tgcgccacta ccagcatgtg     1440

gccgccgtgg atcccgagaa ggcacagcag atgcgcttcc aggtgcatac ccaccttcaa     1500

gtgattgagg agagggtgaa tcagagcctg ggcctgcttg accagaaccc ccacctggct     1560

caggagctgc ggccccaaat ccaggaactc ctccactctg aacacctggg tcccagtgaa     1620

ttggaagccc ctgcccctgg gggcagcagc gaggacaagg gtgggctgca gcctccagat     1680

tccaaggatg acacccccat gacccttcca aaagggtcca cagaacaaga tgctgcatcc     1740

cctgagaaag agaagatgaa cccgctggaa cagtatgagc gaaaggtgaa tgcgtctgtt     1800

ccaaggggtt tccctttcca ctcatcggag attcagaggg atgagctggc accagctggg     1860

acaggggtgt cccgtgaggc tgtgtcgggt ctgctgatca tgggagcggg cggaggctcc     1920

ctcatcgtcc tctccatgct gctcctgcgc aggaagaagc cctacggggc tatcagccat     1980

ggcgtggtgg aggtggaccc catgctgacc ctggaggagc agcagctccg cgaactgcag     2040

cggcacggct atgagaaccc cacttaccgc ttcctggagg aacgaccctg acccggcccc     2100

cttcacccct tcagccgagc ccagacctcc cctcttcctg gagccccaga accccaactc     2160

ccagcctagg gcagcaggga gtcttgaagt gatcatttca cacccttttg tgagacggct     2220

ggaaattctt atttcccctt tccaattcca aaattccatc cctaagaatt cccagatagt     2280

cccagcagcc tccccacgtg gcacctcctc accttaattt attttttaag tttatttatg     2340

gctctttaag gtgaccgcca ccttggtcct agtgtctatt ccctggaatt caccctctca     2400

tgtttcccta ctaacatccc aataaagtcc tcttccctac caggcca                   2447


<210>  250
<211>  2669
<212>  DNA
<213>  homo sapiens

<400>  250
gcggccgcct ccccctcccc ctccccctct ttcttctcct ccctcgtcgc cgccgccgcc       60

gccgccgcct cagccttcgc ctcagccgcc gcccgctccc gcccgcgcgc ggcgggatgg      120

acgatcaatc caggatgctg cagactctgg ccggggtgaa cctggctggc cactcggtgc      180

aggggggcat ggccctgccg cctcccccgc acggccacga aggggcggac ggcgacggca      240

ggaagcagga catcggcgac atcctccacc agatcatgac catcaccgac cagagcttgg      300

acgaggcgca agcaaagaaa catgccctga actgtcacag aatgaaacca gcgctcttca      360

gcgtcctgtg tgagatcaaa gagaaaacag gcatgtaatg aatttactac acatgtgatg      420

aaccttctcc gagaacagag tagaacacgt cccatttctc caaaagagat tgaaagaatg      480

gtgggcatca tccatcgaaa atttagttcc attcagatgc agctcaaaca aagcacttgt      540

gaagcagtta tgattttaag atcaaggttc cttgatgcca gacggaaaag gcgtaacttc      600

agtaaacagg ccacagaaat cttgaatgaa tatttttact cacacctcag caacccctac      660

cccagtgaag aagccaaaga ggagctggcc aagaaatgca gcatcacagt gtcacaggta      720

tccaattggt ttggcaacaa acgaatcagg tacaagaaga acattggcaa gtttcaggaa      780

gaagccaacc tctatgctgc aaagacggcc gtgacagctg cacacgcagt agcagcagct      840

gtgcagaaca accagaccaa ttcgcccacc acaccaaatt ccggttcttc tggttctttt      900

aacctcccaa attctgggga catgttcatg aacatgcaga gtctgaatgg ggattcttac      960

caagggtccc aagtcggagc caatgtgcaa tcacaggtgg ataccctccg tcatgttatc     1020

aatcagacgg gaggctacag tgatggcctt ggaggaaatt cactgtacag tccacataat     1080

ttaaatgcta atggaggctg gcaggacgca acaactccat cttctgtgac ttctcctaca     1140

gaaggcccag gaagtgtgca ctcggatacc tctaactaat ctctggccac acttttccct     1200

gagctacatg ccttgataag tgcattcaga gcaataggag gaaaaggaaa gcgtttttgt     1260

agcccaccat ctacagcttt actgtaaaac cttgtcttat tcgagaactt ggtaaatctg     1320

ttttttaagg aatcataatc atttgtattt atacttaaaa acacacaatg ttaaaaaaaa     1380

taaagcactt tatccaatta ggccaagatt taacattgtt gacagtcctg tagctatttt     1440

atcataattt attatcaata ttttacatta atggtttcac agttgccaat tacttggcct     1500

taagggtaaa aagtacaata tacactaaac ctcaaccgtt aaagcagatg caaaaattca     1560

cctcacctaa attgaacttc ttgcatattt ccattactga cttggattgt ctttctttca     1620

tatcactaat ggagttggaa taaagagctg tttgcctatc cctgttaatg atggttgtgt     1680

ttaagaatct tcctcgtcac gtttgtgttc agatctctta tgttataatt agatcagaga     1740

ctggtagcat cgtttctctc tctgaaagca ccagtgccca gagtctgctc ggtaataaaa     1800

ttatggatcc agattgttct gagagacgaa gatacttgct gctgatagag gtgaaaacga     1860

gattgatccg tctggggttt tacggtgtgc actgggtgct gcacagactt gtcaaggttt     1920

gctacgtcct ctgggcatct gcaaaaggcc ctgctctctg gagtgttgta tatagtgtag     1980

caaaagagta tttatacatc ccaccaatca aaacacagct ttattacctc atgcgaactc     2040

atacaaacca atagaatttc aacatgttct gtagcttaga gtgctcactt actacctctg     2100

aacaatactc acgctgtagt ttgtctcttt cttatctttt tgcatcttgt aattaactct     2160

ttgtttccct tcataaaatg taatgtacat tgtaatcttt taaaagaaaa atcagggttg     2220

cacttgcaac ttttaaaaaa ccgagtgtgg aaacattggg tcttaattca acacaggatc     2280

ggtaaaactg ttgtaaatac tgagaaacat tttgaatgtt cttcatctta ttactaatcc     2340

atgcaaaaaa aaaaaaaaaa gcagcgacta attgtgatgc attcagattt cagtattcag     2400

tactgtatat ttcaccctgt gtaatggggc cccctctcct ttctctcttt ttgtattgta     2460

tgcgattctg aaactgattg agtcatgaaa ataatttgtg gcggtgattc taatgtatta     2520

aaaacgtttc gtgttccttt ctaactggat tacaccctgg attgaaaaag tcttcctcgt     2580

ggtagttata tgtagtttca aacatgaata aactttttgc tttcatgatt aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                                       2669


<210>  251
<211>  2991
<212>  DNA
<213>  homo sapiens

<400>  251
ccgcctggct ttggactctt ctcctcctcc acctcctcct cctcctcccg cgccgccgcc       60

tcctcctcct cttcctctcc gcgccttcgc tacgcgcccg gccgcccgag gcagatccag      120

gcggcggcgg aggcggcggg cgcaggagag cggctcccag ggctgaagtg gccgccacca      180

ccgccgcctg cgcctggagc ccggtggccg ccggacgcac cgcgcggatc gggagcggga      240

gtcgaggcgg cgcggaggcg cagggctcgc aggggcgggc gggcgcgctg gccatgctcc      300

tggacgcggg tccgcagttc ccggccatcg gggtgggcag cttcgcgcgc caccatcacc      360

actccgccgc ggcggcggcg gcggctgccg ccgagatgca ggaccgtgaa ctgagcctgg      420

cggcggcgca gaacggcttc gttgactccg ccgccgcgca catgggagcc ttcaagctca      480

acccgggcgc gcacgagctg tccccgggcc agagctcggc gttcacgtcg cagggccccg      540

gcgcctaccc cggctccgct gcggctgccg ctgcggccgc agcgctcggg ccccacgccg      600

cgcacgttgg ctcctactct gggccgccct tcaactccac ccgggacttc ctgttccgca      660

gccgcggctt cggggactcg gcgccgggcg gcgggcagca cgggctgttc gggccgggcg      720

cgggcggcct gcaccacgcg cactcggacg cgcagggcca cctcctcttc ccgggcctgc      780

cagagcagca cgggccgcac ggctcgcaga atgtgctcaa cgggcagatg cgcctcgggc      840

tgcccggcga ggtgttcggg cgctcggagc aataccgcca ggtggccagc ccgcggaccg      900

acccctactc ggcggcgcaa ctccacaacc agtacggccc catgaatatg aacatgggta      960

tgaacatggc agcagccgcg gcccaccacc accaccacca ccaccaccac cccggtgcct     1020

ttttccgcta tatgcggcag cagtgcatca agcaggagct aatctgcaag tggatcgacc     1080

ccgagcaact gagcaatccc aagaagagct gcaacaaaac tttcagcacc atgcacgagc     1140

tggtgacaca cgtctcggtg gagcacgtcg gcggcccgga gcagagcaac cacgtctgct     1200

tctgggagga gtgtccgcgc gagggcaagc ccttcaaggc caaatacaaa ctggtcaacc     1260

acatccgcgt gcacacaggc gagaaaccct tcccctgccc cttcccgggc tgtggcaaag     1320

tcttcgcgcg ctccgagaac ctcaagatcc acaaaaggac ccacacaggg gagaagccgt     1380

tccagtgtga gtttgagggc tgcgaccggc gcttcgccaa cagcagcgac aggaagaagc     1440

acatgcacgt ccacacctcc gataagccct atctctgcaa gatgtgcgac aagtcctaca     1500

cgcaccccag ctcgctgcgg aagcacatga aggtccatga gtcctccccg cagggctctg     1560

aatcctcccc ggccgccagc tccggctatg agtcgtccac gcccccgggg ctggtgtccc     1620

ccagcgccga gccccagagc agctccaacc tgtccccagc ggcggcggca gcggcggcgg     1680

cggctgcggc ggcggcggcc gcggtgtccg cggtgcaccg gggcggaggc tcgggcagtg     1740

gcggcgcggg aggcggctca ggcggcggca gcggcagtgg cgggggcggc ggcggggcgg     1800

gcggcggggg cggcggcagc tctggcgggg gcagcgggac agccgggggt cacagcggcc     1860

tctcctccaa cttcaatgaa tggtacgtgt gacgggtcgg ggcctctctc cctctccctg     1920

tccccacccc agcgcagcag ccctccccgc agctagcagc gagggcacct tgtgatcatg     1980

ttgttaaaat tatgaatctg atttttatga tgatgaaaat tttaccagca gaaggatttt     2040

ttaaagtttt tttttttttt ttaataataa tctaggcatg aagagcaaaa atatcccttc     2100

cggagtcttt gaagctgaaa atataaaaca aataaaaaat aaaaaaataa aaacccacaa     2160

aaatgttgaa ccaaacctcc ctgctaatct ccatgcccac gttctttccc accctgttcc     2220

cagtcttctg acaaactgtg tacatagcgg actcctcctt tctcctccga ggtggtttta     2280

aaggcttttt ggtgtataga agtttgtcca tttgtaaaac tccggattgc gttcctcccc     2340

gccttccgcc ccttcccttc cctaaagtga tgggctttct cttttctctt tttagtttac     2400

ccggtttctt tttaagtaat gtggaagaaa atggtttatt ttgtattgtg gtattgaata     2460

ttgtgttcct ttttatgagg caacctgatt gtaaacttca tgtaactata gactggaaaa     2520

aatgagccgt gccaaagtct cccttctgtt tcttcagcac attgacccat agcacacaca     2580

tacacaccac caccaacaac gcttgtgaat gtatttttct gttagctggg tttacatgtg     2640

atgttttagt gcttttgcaa gttcaatttg ttagttcctg tatgaaagat tgtgggggaa     2700

aaataaacgt cgtgccgtta gctttttccg taataacacc cttccttctg taaatacccg     2760

ttaccatatt tatccatttg taattaaatt atggtattaa cttgctacag aggaaacaat     2820

atttataaag aatgtttctt aactataaat atgtacaatt gtgggcataa actgtttcag     2880

attttttatt tgaaggtttt aagtggtttg atcatttctt gtgatgtttt gagagtaatg     2940

catacagaaa tataataaaa tgtgttgaaa ctgcaaaaaa aaaaaaaaaa a              2991


<210>  252
<211>  3935
<212>  DNA
<213>  homo sapiens

<400>  252
ccctcggtgc gcgggcacag cagccaggct gccggagagc tgatctcggg gattcgggtg       60

cggagccctt ggcctggagg cgatatgggt ggtccgtggc ccggttcagt cgcttgcagc      120

agcccgggga acaggcctgt ctggccctga gggagtcccc tttctgaagc tgtggtgctt      180

ggacgacctg ctctctacat tgctgggcac ctgtaggtgt ccctcgagag ctcagttttg      240

aggttcaagt cagtgtggcc atgaaggggc tgcctattgg gctgatgctg tgaccctgga      300

gtctgcctct cctgccagtc cccctgcccg gaacatgtgg ctgcggcttg gcccgccctc      360

gctgtccctg agccccaagc ccacggttgg caggagcctg tgcctcaccc tgtggttcct      420

cagtttggcg ctgagggcca gtacccaggc cccagcaccc acagtcaaca ctcactttgg      480

gaagctaagg ggtgcccgag taccactgcc cagtgagatc ctggggcctg tggaccaata      540

cctgggggtg ccctacgcag ctcccccgat cggcgagaaa cgtttcctgc cccctgaacc      600

acccccatcc tggtcgggca tccggaacgc cacacacttt cccccagtgt gcccccagaa      660

catccacaca gctgtgcccg aagtcatgct gccggtctgg ttcactgcca acttggatat      720

cgtcgctact tacatccagg agcccaacga agactgtctc tacctgaacg tctatgtgcc      780

gacggaggat ggatccggcg ctaagaaaca gggcgaggac ttagcggata atgacgggga      840

tgaagatgaa gacatccggg acagtggtgc taaacccgtc atggtctaca tccacggagg      900

ctcttacatg gaagggacag gcaacatgat tgatggcagc atcctcgcca gttatggcaa      960

tgtcatcgtc atcaccctca actatcgggt tggagtgcta ggtttcctga gtactggaga     1020

tcaggctgcc aagggcaact atgggctcct tgaccagatc caggccctcc gctgggtgag     1080

cgagaatatt gccttcttcg ggggagaccc ccgccggatc actgtctttg gctcgggcat     1140

tggtgcatcc tgcgtcagcc tcctcacgtt gtcacatcac tcagagggac ttttccagag     1200

agccatcatc caaagtggct ctgctctgtc cagctgggct gtgaactacc aaccagtgaa     1260

gtacaccagc ctgctggcag acaaagtggg ctgtaatgtg ctggacaccg tggatatggt     1320

ggactgtctt cggcaaaaga gtgccaagga gctggtagag caggacatcc agccagcccg     1380

ctaccacgtg gcctttggcc ctgtgattga tggtgatgtc attcctgatg accctgagat     1440

cctcatggag cagggcgagt tcctcaacta tgacatcatg ctaggtgtca accagggcga     1500

gggtctcaag tttgtggaag gggtggtgga ccctgaggat ggtgtctctg gcactgactt     1560

tgactattcc gtctccaatt ttgtggacaa tctgtatggc tatcctgagg gtaaggacac     1620

cctgcgagag accatcaagt tcatgtatac agactgggca gaccgtgaca accctgagac     1680

ccgccgtaaa acactggtgg cactcttcac tgaccaccag tgggtggagc cctcagtggt     1740

gacagccgat ctgcatgccc gctacggctc gcctacctac ttctacgcct tctatcatca     1800

ctgccagagc ctcatgaagc ctgcttggtc agatgcagct catggggatg aagtacccta     1860

tgtttttggg gttcctatgg taggccccac tgaccttttc ccctgcaact tctccaagaa     1920

tgatgttatg ctcagtgctg tcgtcatgac ctattggacc aactttgcca agactgggga     1980

tcccaacaag ccggtccccc aggacaccaa gttcattcac accaaggcca accgctttga     2040

ggaagtggcc tggtccaaat acaatccccg agaccagctc taccttcaca tcgggctgaa     2100

accaagggtc cgagatcatt accgggccac taaggtggcc ttttggaaac atctggtgcc     2160

ccacctatac aacctgcatg acatgttcca ctatacgtcc accaccacca aagtgccgcc     2220

tccggatacc acccacagct cccacatcac ccgcaggccc aatggcaaga cctggagcac     2280

caagcggcca gccatctcac ctgcctacag caacgagaat gcccaggggt cctggaacgg     2340

ggaccaggat gcagggccac tcctggtgga gaaccctcgt gactactcca ctgaattaag     2400

tgtcaccatc gccgtggggg cctccctcct gttccttaac gttctggcct tcgctgccct     2460

ctactaccgt aaggacaaac ggcgccagga gcccctgcgg cagcctagcc ctcagcgggg     2520

agccggggcc ccggagttgg gagctgctcc agaggaggag ctggcagcat tacaactggg     2580

ccccacccac cacgagtgtg aggccggtcc cccccatgac acgctgcgcc tcactgcatt     2640

gcccgactac accctgaccc tgcggcgctc cccggatgac atcccactca tgacccccaa     2700

caccatcact atgatcccca actccctggt agggctgcag acattgcacc cctataacac     2760

ctttgccgca gggttcaaca gtaccgggct gccccactca cactccacta cccgggtata     2820

gctccaactc agagcacagc caatctccag gctccctccc tcccagatcc aggaacacat     2880

gcacacacac acacacacac acgcagacac acacacacac acacatatat gtatacgcac     2940

gcacccacac cctacagcag atccacctgc acaaacatag acagatgtgg acatgcaccc     3000

gcatgtacaa aaacacaaat acggaagtaa acctgaacaa accctttaaa tggggacgca     3060

gatgagtcct cggtaaaccg aggacccatg aaacagcagc tgaagccagc tccctgaatc     3120

tgaccacaga cactcctggg gggcctgaaa gcaacagctg gacaccccct tggtgctcgc     3180

cttcggcctc tcttggaact gcaccaccga ccaactccag acttgggagc tttaaagagc     3240

aggatagctc ttcctcccca ggacttggtc ttttttctgg gtcttgtttt gttgattttt     3300

cttttttaat tttggaacaa atgcttttcc aacccatgag tgctaagagc ctctggaagg     3360

gagggcttca ggcccgaagg tctctctggc tctaggaccc ccagtgctca cacaatcaga     3420

ccaaggaaca agacccccag gaaggaaaca gatttaagca agaccatggg gtggaaggag     3480

aaaggggcta gcactggatg gagctggagg gtcgtagggg agagatctcc aactctctct     3540

gtgtccgtgt ggagggctgc agagcctgca gggtgacctg cttccccaaa ggccaacagc     3600

attggcctgg ccagaccagg tgaccttaga tttggtgaac aacgtactat ggaagccaca     3660

tcactattgg gcccccaggt ctgatctggg ttttgcctct gcccttgggg aaatgctatc     3720

agaaattcgc cccattttct ttacagtctt ttgtgtctgt catttctctt tcaaaaaggc     3780

ggtgtttttt gttgttgttg gttttttttt ttttttaaag aaaagttctt aaaacactaa     3840

cggaaaccca tggagtttgt cctttgtaaa aattttaaac acagtgtctt gatataaaaa     3900

taaaaaatcc agttagcact cccaaaaaaa aaaaa                                3935


<210>  253
<211>  2293
<212>  DNA
<213>  homo sapiens

<400>  253
atttgggaga gtgctgtgac tcatgctgga ctctaaccca cgagggtttc tcagagtcag       60

cagctggggg atgaagaagt gaaaagtgac tggcaggaaa ttctgcaagc aaggaaaggg      120

aaagagaaat gaactggtgc aggtctgcgg gaagagaatg aggctggatc ctcaaaatca      180

caggaggaag caggcccaga cctcagaggc agaaagagaa agaaaccaga gcttagagtc      240

aggaggagga aaccagaccc cggagccaca aggagagggc tggatccccg gctcagaggg      300

aagagtgtcg ccgcctctgc ctgcgtagcc ccggccatgg ctctgtagcc tcgacccctt      360

tgtgcccccg gcccgtctcc gcgctcacca cgcctgcgct ctccgctccc accttctttc      420

ttcagccgag gccgccgccg cctctccttg ctgcagccat ggagtcttcc actttcgcct      480

tggtgcctgt cttcgcccac ctgagcatcc tccagagcct cgtgccagct gctggtgcag      540

cctctcctgt tgccatcagt gcccagcacc tgtgctacag ccatgtcact cctggcgacc      600

ctggggctgg agctggacag ggccctgctc ccagctagtg ggctgggatg gctcgtagac      660

tatgggaaac tccccccggc ccctgccccc ctggctccct atgaggtcct tgggggagcc      720

ctggagggcg ggcttccagt ggggggagag cccctggcag gtgatggctt ctctgactgg      780

atgactgagc gagttgattt cacagctctc ctccctctgg agcctccctt accccccggc      840

accctccccc aaccttcccc aaccccacct gacctggaag ctatggcctc cctcctcaag      900

aaggagctgg aacagatgga agacttcttc ctagatgccc cgcccctccc accaccctcc      960

ccgccgccac taccaccacc accactacca ccagccccct ccctccccct gtccctcccc     1020

tcctttgacc tcccccagcc ccctgtcttg gatactctgg acttgctggc catctactgc     1080

cgcaacgagg ccgggcagga ggaagtgggg atgccgcctc tgcccccgcc acagcagccc     1140

cctcctcctt ctccacctca accttctcgc ctggccccct acccacatcc tgccaccacc     1200

cgaggggacc gcaagcaaaa gaagagagac cagaacaagt cggcggctct gaggtaccgc     1260

cagcggaagc gggcagaggg tgaggccctg gagggcgagt gccaggggct ggaggcacgg     1320

aatcgcgagc tgaaggaacg ggcagagtcc gtggagcgcg agatccagta cgtcaaggac     1380

ctgctcatcg aggtttacaa ggcccggagc cagaggaccc gtagctgcta gaagggcagg     1440

ggtgtggctt ctgggggctg gtcttcagct ctggcgcctt catccccctg cctctacctt     1500

cattccaaac ccctctcggc cgggtgcagt ggcttatgct tgtaatccca gcactttggg     1560

aggccaaggc aggaggatcg tttgaggcca ggaggtcaat accagcctgg gcaacatagt     1620

aagaccctgt ctctattaaa aaaaaaaaat caacccttct tccccaccaa accacccaac     1680

tcctctctac tcttatcctt ttatcctctg tctctgctta tcacctctct tgcgtatttc     1740

tggatctcct tccctccttt ctcgtccaaa tcatgaaatg tttggcctta gtcaatgtct     1800

atgcccgtca cataacagcc gaggcaccga ggcccacagg gaagcagctg ggagcttgga     1860

aacctggtct cttgaatttc aaacctggtt tcttacaggt ggttgtctgg ggtgggtgga     1920

gtggcgacag gatagagctg aaggactatg caaatgagga agtaagtcag ggcgggcttt     1980

gagaagggga cccatatcct acaggcaaaa agcaggctag gtgaccttgg gacactacgc     2040

taagggaggg aggctaaagg cggccaggtt tgcagtgcgg gaagatgagc aggccagtgg     2100

gaggaggggc agggcagggc tgtagttggt gactgggtgt tcattttagc tctaagaaaa     2160

aaaatcagtg tttcgtgaag gtgttggaga ggggctgtgt ctgggtgagg gatggcgggg     2220

tactgatttt tttgggaggt tatgagcaaa aataaaacga aacatttcct ctggcaaaaa     2280

aaaaaaaaaa aaa                                                        2293


<210>  254
<211>  3415
<212>  DNA
<213>  homo sapiens

<400>  254
ttccgcggag gtcctgcctc tccctgcgga cgggcgctga ttggcccgtt tgaaatgcgc       60

caggcgggag ctcacctggg ctcttagcgt cgccgccggc ttcgcagagc accgcgcctt      120

agccgcgaag ttctagttct tgctgccggt cctaacgtcc cgcagtcttc gccagccagc      180

cgtcccgcat gcgcgtttgg gcggcgtgga gcctgctgcc atgaagtcag cgagagctaa      240

gacaccccgg aaacctaccg tgaaaaaagg gtcccaaacg aaccttaaag acccagttgg      300

ggtatactgt agggtgcgcc cactgggctt tcctgatcaa gagtgttgca tagaagtgat      360

caataataca actgttcagc ttcatactcc tgagggctac agactcaacc gaaatggaga      420

ctataaggag actcagtatt catttaaaca agtatttggc actcacacca cccagaagga      480

actctttgat gttgtggcta atcccttggt caatgacctc attcatggca aaaatggtct      540

tctttttaca tatggtgtga cgggaagtgg aaaaactcac acaatgactg gttctccagg      600

ggaaggaggg ctgcttcctc gttgtttgga catgatcttt aacagtatag ggtcatttca      660

agctaaacga tatgttttca aatctaatga taggaatagt atggatatac agtgtgaggt      720

tgatgcctta ttagaacgtc agaaaagaga agctatgccc aatccaaaga cttcttctag      780

caaacgacaa gtagatccag agtttgcaga tatgataact gtacaagaat tctgcaaagc      840

agaagaggtt gatgaagata gtgtctatgg tgtatttgtc tcttatattg aaatatataa      900

taattacata tatgatctat tggaagaggt gccgtttgat cccataaaac ccaaacctcc      960

acaatctaaa ttgcttcgtg aagataagaa ccataacatg tatgttgcag gatgtacaga     1020

agttgaagtg aaatctactg aggaggcttt tgaagttttc tggagaggcc agaaaaagag     1080

acgtattgct aatacccatt tgaatcgtga gtccagccgt tcccatagcg tgttcaacat     1140

taaattagtt caggctccct tggatgcaga tggagacaat gtcttacagg aaaaagaaca     1200

aatcactata agtcagttgt ccttggtaga tcttgctgga agtgaaagaa ctaaccggac     1260

cagagcagaa gggaacagat tacgtgaagc tggtaatatt aatcagtcac taatgacgct     1320

aagaacatgt atggatgtcc taagagagaa ccaaatgtat ggaactaaca agatggttcc     1380

atatcgagat tcaaagttaa cccatctgtt caagaactac tttgatgggg aaggaaaagt     1440

gcggatgatc gtgtgtgtga accccaaggc tgaagattat gaagaaaact tgcaagtcat     1500

gagatttgcg gaagtgactc aagaagttga agtagcaaga cctgtagaca aggcaatatg     1560

tggtttaacg cctgggagga gatacagaaa ccagcctcga ggtccagttg gaaatgaacc     1620

attggttact gacgtggttt tgcagagttt tccacctttg ccatcatgcg aaattttgga     1680

tatcaacgat gagcagacac ttccaaggct gattgaagcc ttagagaaac gacataactt     1740

acgacaaatg atgattgatg agtttaacaa acaatctaat gcttttaaag ctttgttaca     1800

agaatttgac aatgctgttt taagtaaaga aaaccacatg caagggaaac taaatgaaaa     1860

ggagaagatg atctcaggac agaaattgga aatagaacga ctggaaaaga aaaacaaaac     1920

tttagaatat aagattgaga ttttagagaa aacaactact atctatgagg aagataaacg     1980

caatttgcaa caggaacttg aaactcagaa ccagaaactt cagcgacagt tttctgacaa     2040

acgcagatta gaagccaggt tgcaaggcat ggtgacagaa acgacaatga agtgggagaa     2100

agaatgtgag cgtagagtgg cagccaaaca gctggagatg cagaataaac tctgggttaa     2160

agatgaaaag ctgaaacaac tgaaggctat tgttaccgaa cctaaaactg agaagccaga     2220

gagaccctct cgggagcgag atcgagaaaa agttactcaa agatctgttt ctccatcacc     2280

tgtgccttta ctctttcaac ctgatcagaa cgcaccacca attcgtctcc gacacagacg     2340

atcacgctct gcaggagaca gatgggtaga tcataagccc gcctctaaca tgcaaactga     2400

aacagtcatg cagccacatg tccctcatgc catcacagta tctgttgcaa atgaaaaggc     2460

actagctaag tgtgagaagt acatgctgac ccaccaggaa ctagcctccg atggggagat     2520

tgaaactaaa ctaattaagg gtgatattta taaaacaagg ggtggtggac aatctgttca     2580

gtttactgat attgagactt taaagcaaga atcaccaaat ggtagtcgaa aacgaagatc     2640

ttccacagta gcacctgccc aaccagatgg tgcagagtct gaatggaccg atgtagaaac     2700

aaggtgttct gtggctgtgg agatgagagc aggatcccag ctgggacctg gatatcagca     2760

tcacgcacaa cccaagcgca aaaagccatg aactgacagt cccagtactg aaagaacatt     2820

ttcatttgtg tggatgattt ctcgaaagcc atgccagaag cagtcttcca ggtcatcttg     2880

tagaactcca gctttgttga aaatcacgga cctcagctac atcatacact gacccagagc     2940

aaagctttcc ctatggttcc aaagacaact agtattcaac aaaccttgta tagtatatgt     3000

tttgccatat ttaatattaa tagcagagga agactccttt tttcatcact gtatgaattt     3060

tttataatgt ttttttaaaa tatatttcat gtatacttat aaactaattc acacaagtgt     3120

ttgtcttaga tgattaagga agactatatc tagatcatgt ctgatttttt attgtgactt     3180

ctccagccct ggtctgaatt tcttaaggtt ttataaacaa atgctgctat ttattagctg     3240

caagaatgca ctttagaact atttgacaat tcagactttc aaaataaaga tgtaaatgac     3300

tggccaataa taaccatttt aggaaggtgt tttgaattct gtatgtatat attcactttc     3360

tgacatttag atatgccaaa agaattaaaa tcaaaagcac taagaaatac aaaaa          3415


<210>  255
<211>  9717
<212>  DNA
<213>  homo sapiens

<400>  255
gcctgctcca agggaaggat caggagagaa gaaacgcaaa tcccagaacc gtgccaacat       60

ataaaacccc acattaaggg ttgtacagtg cactgggatt tctcaagtca cccgcttggt      120

cctcttccaa gtatacttta cttcctttca ttcctctcta aaactttttt aaaaactttc      180

actcctgctc taaaagttat cttggtttct tactctacct tatgcccctt gggcgaattt      240

tttcctctga ggagggaaga atagagttgc tgctgcagac acatcagatt ccctactggt      300

aacagctgga gtgcgtcacc tctgacaaaa ttctggggac gctgggaaca ctgaatcaac      360

atgggcaatg agaacagcac ctcggacaac cagaggactt tatcagctca gactccaagg      420

tccgcgcagc cacccgggaa cagtcagaat ataaaaagga agcagcagga cacgcccgga      480

agccctgacc acagagacgc gtccagcatt ggcagcgttg ggcttggagg cttctgcacc      540

gcttctgaga gttctgccag cctggatcca tgccttgtgt ccccagaggt gactgagcca      600

aggaaggacc cacagggagc cagggggcca gaaggttctt tgctgcccag cccaccaccg      660

tcccaggagc gagagcaccc ctcgtcctcc atgccctttg ccgagtgtcc cccggaaggt      720

tgcttggcaa gtccagcagc ggcacctgaa gatggtcctc agactcagtc tcccaggagg      780

gaacctgccc caaatgcccc aggagacatc gcggcggcat ttcccgctga gagggacagc      840

tctactccat accaagagat tgctgccgtc cccagtgctg gaagagagag acagccgaag      900

gaagaaggac agaagtcctc cttctccttc tccagtggca tcgaccagtc acctggaatg      960

tcgccagtac ccctcagaga gccaatgaag gcaccgctgt gtggagaggg ggaccagcct     1020

ggtggttttg agtcccaaga gaaagaggct gcaggtggct ttccccctgc agagtccagg     1080

cagggggtgg cttctgtgca agtgacccct gaggcccctg ctgcagccca gcagggcaca     1140

gaaagctcag cggtcttgga gaagtccccc ctaaaaccca tggccccgat cccacaagat     1200

ccagccccaa gagcctcaga cagagaaaga ggccaagggg aggcgccgcc tcagtattta     1260

acagatgact tggaattcct cagggcctgc catctcccta ggagcaattc aggggctgcc     1320

ccagaagcag aagtgaatgc cgcttcccag gagagctgcc agcagccagt gggagcatat     1380

ctgccgcacg cagagctgcc ctggggcttg ccaagtcctg ccctggtgcc agaggctggg     1440

ggctctggga aggaggctct ggacaccatt gatgttcagg gtcacccaca gacagggatg     1500

cgaggaacca agcccaatca agttgtctgt gtggcagcag gcggccagcc cgaagggggt     1560

ttgcctgtga gccctgaacc ttccctgctc actccgactg aggaagcaca tccagcttca     1620

agcctcgctt cattcccagc tgctcagatt cctattgctg tagaagaacc tggatcatca     1680

tccagggaat cagtttccaa ggctgggatg ccagtttctg cagatgcagc caaagaggtg     1740

gtggatgcag ggttggtggg actggagagg caggtgtcag atcttggaag caagggagag     1800

catccagaag gggaccctgg agaggttcct gccccatcac cccaggagag gggagagcac     1860

ttgaacacgg agcaaagcca tgaggtccaa ccaggagtac caccccctcc tcttcccaag     1920

gagcaaagcc atgaggtcca accaggagca ccaccccctc ctcttcccaa ggcaccaagt     1980

gaaagtgcca gagggccacc ggggccaacg gatggagcca aggtccatga agattccaca     2040

agcccagccg tggctaaaga aggaagcaga tcacctggtg acagccctgg aggaaaggag     2100

gaagccccag agccacctga tggtggagac ccagggaacc tgcaaggaga ggactctcag     2160

gctttcagca gcaagcgtga tccagaagta ggcaaagatg agctttcaaa gccaagcagt     2220

gatgcagaga gcagagacca tcccagctca cactcagcac agccacccag aaaggggggt     2280

gctgggcaca cggacgggcc ccactctcag acagcagagg ctgatgcatc tggcctacca     2340

cacaagctgg gtgaggagga ccccgtcctg ccccctgtgc cagatggagc tggtgagccc     2400

actgttcccg aaggagccat ctgggagggg tcaggattgc agcccaaatg tcctgacacc     2460

cttcagagca gggaaggatt gggaagaatg gagtctttcc tgactttaga atcagagaaa     2520

tcagattttc caccaactcc tgttgcagag gttgcaccca aagcccagga aggtgagagc     2580

acattggaaa taaggaagat gggcagctgt gatggggagg gcttgctgac gtccccagat     2640

caaccccgcg ggccggcgtg tgatgcgtcg agacaggaat ttcatgctgg ggtgccacat     2700

cccccccagg gggagaactt ggcagcagac ctggggctca cggcactcat cctggaccaa     2760

gatcagcagg gaatcccatc ctgcccaggg gaaggctgga taagaggagc tgcatccgag     2820

tggcccctac tatcttctga gaagcatctc cagccatccc aggcacaacc agagacatcc     2880

atctttgacg tgctcaagga gcaggcccag ccacctgaaa atgggaaaga gacttctcca     2940

agccatccag gttttaagga ccagggagca gattcttccc aaatccatgt acctgtggaa     3000

cctcaggaag ataacaactt gcccactcat ggaggacagg agcaggcttt gggatcagaa     3060

cttcaaagtc agctccccaa aggcaccctg tctgatactc caacttcatc tcccactgac     3120

atggtttggg agagttctct gacagaagag tcagaattgt cagcaccaac gagacagaag     3180

ttgcctgcac taggggagaa gcggccagag ggagcatgcg gtgatggtca gtcctcgagg     3240

gtctcgcctc cagcagcaga tgtcttaaaa gacttttctc ttgcagggaa cttcagcaga     3300

aaggaaactt gctgcactgg gcaggggcca aacaagtctc aacaggcatt ggctgatgcc     3360

ttggaagaag gcagccagca tgaagaagca tgtcaaaggc atccaggagc ttctgaagca     3420

gctgatggtt gttccccact ctggggcttg agtaagaggg agatggcaag tggaaacaca     3480

ggggaggccc caccttgtca gcctgactca gtagctctcc tggatgcagt tccctgcctg     3540

ccagccctgg cgcccgccag ccccggagtc acacccaccc aggatgcccc agagacagag     3600

gcatgtgatg aaacccagga aggcaggcag caaccagtgc cggccccgca gcagaaaatg     3660

gagtgccggg ccacttcgga tgcagagtcc ccaaagcttc ttgcaagttt cccatcagct     3720

ggggagcaag gtggtgaagc cggggctgct gagactggtg gcagcgctgg tgcaggagac     3780

ccaggaaagc agcaggctcc ggagaaacct ggagaagcta ctttgagttg tggcctcctt     3840

cagactgagc actgccttac ctccggggag gaagcttcta cctctgccct acgtgagtcc     3900

tgccaagctg agcaccccat ggccagctgc caggatgcct tgctgccagc cagagagctg     3960

ggtgggattc ccaggagcac catggatttt tctacacacc aggctgtccc agacccaaag     4020

gagctcctgc tgtctgggcc accagaagtg gctgctcctg acacccctta cctgcatgtc     4080

gacagtgctg cccagagagg agcagaagac agtggagtga aagctgtttc ctctgcagac     4140

cccagagctc ctggcgaaag cccctgtcct gtaggggagc ccccacttgc cttggaaaat     4200

gctgcctcct tgaagctgtt tgctggctcc ctcgcccccc tgttgcaacc aggagctgca     4260

ggtggggaaa tccctgcagt gcaagccagc agtggtagtc ccaaagccag aaccactgag     4320

ggaccagtgg actccatgcc atgcctggac cggatgccac ttctggccaa gggcaagcag     4380

gcaacagggg aagagaaagc agcaacagct ccaggtgcag gtgccaaggc cagtggggag     4440

ggcatggcag gtgatgcagc aggagagaca gagggcagca tggagaggat gggagagcct     4500

tcccaggacc caaagcaggg cacatcaggt ggtgtggaca caagctctga gcaaatcgcc     4560

accctcactg gcttcccaga cttcagggag cacatcgcca agatcttcga gaagcctgtg     4620

ctcggagccc tggccacacc tggagaaaag gcaggagctg ggaggagtgc agtgggtaaa     4680

gacctcacca ggccattggg cccagagaag cttctagatg ggcctccagg agtggatgtc     4740

acccttctcc ctgcacctcc tgctcgactc caggtggaga agaagcaaca gttggctgga     4800

gaggctgaga tttcccatct ggctctgcaa gatccagctt cagacaagct tctgggtcca     4860

gcagggctga cctgggagcg gaacttgcca ggtgccggtg tggggaagga gatggcaggt     4920

gtcccaccca cactgaggga agacgagagg ccagaggggc ctggggcagc ctggccaggc     4980

ctggaaggcc aggcttactc acagctggag aggagcaggc aggaattagc ttcaggtctt     5040

ccttcaccag cagctactca ggagctccct gtggagagag ctgctgcctt ccaggtggct     5100

ccccatagcc atggagaaga ggccgtggcc caagacagaa ttccttctgg aaagcagcac     5160

caggaaacat ctgcctgcga cagtccacat ggagaagatg gtcccgggga ctttgctcac     5220

acaggggttc caggacatgt gccaaggtcc acgtgtgccc cttctcctca gagggaggtt     5280

ttgactgtgc ctgaggccaa cagtgagccc tggacccttg acacgcttgg gggtgaaagg     5340

agacccggag tcactgctgg catcttggaa atgcgaaatg ccctgggcaa ccagagcacc     5400

cctgcaccac caactggaga agtggcagac actcccctgg agcctggcaa ggtggcaggc     5460

gctgctgggg aagcagaggg tgacatcacc ctgagcacag ctgagacaca ggcatgtgcg     5520

tccggtgatc tgcctgaagc aggtactacg aggacattct ccgttgtggc aggtgacttg     5580

gtgctgccag gaagctgtca ggacccagcc tgctctgaca aggctccggg gatggagggt     5640

acagctgccc ttcatgggga cagcccagcc aggccccagc aggctaagga gcagccaggg     5700

cctgagcgcc ccattccagc tggggatggg aaggtgtgcg tctcctcacc tccagagcct     5760

gacgaaactc acgacccgaa gctgcaacat ttggctccag aagagctcca cactgacaga     5820

gagagcccca ggcctggccc atccatgtta ccttcggttc ctaagaagga tgctccaaga     5880

gtcatggata aagtcacttc agatgagacc agaggtgcgg aaggaacaga aagttcacct     5940

gtggcagatg atatcatcca gcccgctgcc cccgcagacc tggaaagccc aaccttagct     6000

gcctcttcct accacggtga tgttgttggc caggtctcta cggatctgat agcccagagc     6060

atctccccag ctgctgccca tgcgggtctt cctccctcgg ctgcagaaca catagtttcg     6120

ccatctgccc cagctggtga cagagtagaa gcttccactc cctcctgccc agatccggcc     6180

aaggacctca gcaggagttc cgattctgaa gaggcatttg agaccccgga gtcaacgacc     6240

cctgtcaaag ctccgccagc tccaccccca ccaccccccg aagtcatccc agaacccgag     6300

gtcagcacac agccaccccc ggaagaacca ggatgtggtt ctgagacagt ccctgtccct     6360

gatggcccac ggagcgactc ggtggaagga agtcccttcc gtcccccgtc acactccttc     6420

tctgccgtct tcgatgaaga caagccgata gccagcagtg ggacttacaa cttggacttt     6480

gacaacattg agcttgtgga tacctttcag accttggagc ctcgtgcctc agacgctaag     6540

aatcaggagg gcaaagtgaa cacacggagg aagtccacgg attccgtccc catctctaag     6600

tctacactgt cccggtcgct cagcctgcaa gccagtgact ttgatggtgc ttcttcctca     6660

ggcaatcccg aggccgtggc ccttgcccca gatgcatata gcacgggttc cagcagtgct     6720

tctagtaccc ttaagcgaac taaaaaaccg aggccgcctt ccttaaaaaa gaaacagacc     6780

accaagaaac ccacagagac ccccccagtg aaggagacgc aacaggagcc agatgaagag     6840

agccttgtcc ccagtgggga gaatctagca tctgagacga aaacggaatc tgccaagacg     6900

gaaggtccta gcccagcctt attggaggag acgccccttg agcccgctgt ggggcccaaa     6960

gctgcctgcc ctctggactc agagagtgca gaaggggttg tccccccggc ttctggaggt     7020

ggcagagtgc agaactcacc ccctgtcggg aggaaaacgc tgcctcttac cacggccccg     7080

gaggcagggg aggtaacccc atcggatagc ggggggcaag aggactctcc agccaaaggg     7140

ctctccgtaa ggctggagtt tgactattct gaggacaaga gtagttggga caaccagcag     7200

gaaaaccccc ctcctaccaa aaagataggc aaaaagccag ttgccaaaat gcccctgagg     7260

aggccaaaga tgaaaaagac acccgagaaa cttgacaaca ctcctgcctc acctcccaga     7320

tcccctgctg aacccaatga catccccatt gctaaaggta cttacacctt tgatattgac     7380

aagtgggatg accccaattt taaccctttt tcttccacct caaaaatgca ggagtctccc     7440

aaactgcccc aacaatcata caactttgac ccagacacct gtgatgagtc cgttgacccc     7500

tttaagacat cctctaagac ccccagctca ccttctaaat ccccagcctc ctttgagatc     7560

ccagccagtg ctatggaagc caatggagtg gacggggatg ggctaaacaa gcccgccaag     7620

aagaagaaga cgcccctaaa gactgacaca tttagggtga aaaagtcgcc aaaacggtct     7680

cctctctctg atccaccttc ccaggacccc accccagctg ctacaccaga aacaccacca     7740

gtgatctctg cggtggtcca cgccacagat gaggaaaagc tggcggtcac caaccagaag     7800

tggacgtgca tgacagtgga cctagaggct gacaaacagg actacccgca gccctcggac     7860

ctgtccacct ttgtaaacga gaccaaattc agttcaccca ctgaggagtt ggattacaga     7920

aactcctatg aaattgaata tatggagaaa attggctcct ccttacctca ggacgacgat     7980

gccccgaaga agcaggcctt gtaccttatg tttgacactt ctcaggagag ccctgtcaag     8040

tcatctcccg tccgcatgtc agagtccccg acgccgtgtt cagggtcaag ttttgaagag     8100

actgaagccc ttgtgaacac tgctgcgaaa aaccagcatc ctgtcccacg aggactggcc     8160

cctaaccaag agtcacactt gcaggtgcca gagaaatcct cccagaagga gctggaggcc     8220

atgggcttgg gcaccccttc agaagcgatt gaaattacag ctcccgaggg ctcctttgcc     8280

tctgctgacg ccctcctcag caggctagct caccccgtct ctctctgtgg tgcacttgac     8340

tatctggagc ccgacttagc agaaaagaac cccccactat tcgctcagaa actccaggag     8400

gagttagagt ttgccatcat gcggatagaa gccctgaagc tggccaggca gattgctttg     8460

gcttcccgca gccaccagga tgccaagaga gaggctgctc acccaacaga cgtctccatc     8520

tccaaaacag ccttgtactc ccgcatcggg accgctgagg tggagaaacc tgcaggcctt     8580

ctgttccagc agcccgacct ggactctgcc ctccagatcg ccagagcaga gatcataacc     8640

aaggagagag aggtctcaga atggaaagat aaatatgaag aaagcaggcg ggaagtgatg     8700

gaaatgagga aaatagtggc cgagtatgag aagaccatcg ctcagatgat agaggacgaa     8760

cagagagaga agtcagtctc ccaccagacg gtgcagcagc tggttctgga gaaggagcaa     8820

gccctggccg acctgaactc cgtggagaag tctctggccg acctcttcag aagatatgag     8880

aagatgaagg aggtcctaga aggcttccgc aagaatgaag aggtgttgaa gagatgtgcg     8940

caggagtacc tgtcccgggt gaagaaggag gagcagaggt accaggccct gaaggtgcac     9000

gcggaggaga aactggacag ggccaatgct gagattgctc aggttcgagg caaggcccag     9060

caggagcaag ccgcccacca ggccagcctg cggaaggagc agctgcgagt ggacgccctg     9120

gaaaggacgc tggagcagaa gaataaagaa atagaagaac tcaccaagat ttgtgacgaa     9180

ctgattgcca aaatggggaa aagctaactc tgaaccgaat gttttggact taactgttgc     9240

gtgcaatatg accgtcggca cactgctgtt cctccagttc catggacagg ttctgttttc     9300

actttttcgt atgcactact gtatttcctt tctaaataaa attgatttga ttgtatgcag     9360

tactaaggag actatcagaa tttcttgcta ttggtttgca ttttcctagt ataattcata     9420

gcaagttgac ctcagagttc ctgtatcagg gagattgtct gattctctaa taaaagacac     9480

attgctgacc ttggccttgc cctttgtaca caagttccca gggtgagcag cttttggatt     9540

taatatgaac atgtacagcg tgcataggga ctcttgcctt aaggagtgta aacttgatct     9600

gcatttgctg atttgttttt aaaaaaacaa gaaatgcatg tttcaaataa aattctctat     9660

tgtaaataaa attttttctt tggatcttgg caataaaaaa aaaaaaaaaa aaaaaaa        9717


<210>  256
<211>  16114
<212>  DNA
<213>  homo sapiens

<400>  256
atggacttag caccagacag ggctactggc cgcccgtggc tcccgttgca cactctatca       60

gtatctcagc tccttcgagt gttttggcta ctgtcattgc ttccggggca ggcctgggtc      120

cacggggccg agccgcgcca ggtgttccaa gtgctggaag agcaacctcc aggcactctg      180

gtaggcacca tccagacgcg ccccggcttc acctacaggc tcagcgaaag ccacgccctg      240

tttgccataa acagtagcac cggagccctg tacaccacct ccaccatcga ccgcgagagc      300

ctgcccagcg acgtgatcaa cctggtggtc ctttccagcg cgcccaccta ccccaccgaa      360

gtgcgagtgc tggtgcggga cctcaatgac aacgcccccg ttttcccgga cccctctatc      420

gtggtcactt tcaaggaaga cagtagcagc ggacgccaag tcatcttaga caccgccacc      480

gactcggaca tcggctcaaa cggtgtggac caccgctcct accgcatcat ccgcggcaat      540

gaggcggggc gcttccgtct ggacatcacc ctgaacccga gcggcgaggg agcgttcctg      600

catctggtgt ccaagggcgg actggaccgt gaggtcactc cgcagtacca gctcctggtt      660

gaggtggagg acaagggtga gcctaagcgg cggggctacc ttcaggtaaa cgtgactgtg      720

caagacatta atgacaaccc cccggttttt ggcagttctc actaccaggc gggggtgcct      780

gaggacgcgg ttgtgggttc cagcgtcctc caggtggcgg cggcggacgc ggacgagggc      840

accaacgcgg acatccgcta tcgcctgcag gacgagggga cccccttcca aatggaccct      900

gagacgggac ttatcacggt gcgggagccc ctggacttcg aagctcggcg ccaatactcg      960

cttacggtgc aggcgatgga cagaggcgtg ccttccctca ctgggcgcgc cgaggcgctg     1020

attcagctgc tggacgtgaa tgacaatgac ccggtagtga agttccgcta cttcccggcc     1080

acctcgcgct acgcctcggt agatgagaat gctcaagtgg gcaccgtggt ggctctgctc     1140

accgtgacgg acgcagattc tcccgcggcc aacgggaaca tctccgtgca aattctcggg     1200

ggcaatgagc agcgccactt tgaagtgcaa agcagcaaag tgccgaacct gagcctaatc     1260

aaggtggcca gcgccttgga ccgcgagcgc atcccttcct acaacctcac agtttccgtc     1320

tctgataact acggggcgcc ccctggcgca gcagtccagg cgcgctcttc tgtggcaagc     1380

ctggtgattt ttgttaatga catcaatgac catcctcctg tcttttcaca gcaagtgtac     1440

agagtgaacc tgagcgagga ggcgcctccg ggaagctatg tgagtgggat atctgccact     1500

gatggcgact ctggtctcaa tgctaatctg cgttacagca ttgtctctgg caatggactg     1560

ggatggttcc atatcagtga acatagcggc ctcgtgacca ctgggtcctc tgggggcctg     1620

gaccgtgaac ttgcttccca gattgttctg aatataagtg cccgggacca gggagttcac     1680

cccaaggtgt cctatgccca gcttgtagta actctcctag atgtgaatga tgaaaagcca     1740

gtatttagcc agccagaagg gtatgatgtg tctgtggttg agaatgcccc aacagggaca     1800

gaactgttga tgctcagggc aactgacggg gacctgggtg acaacggaac agtgcgcttc     1860

tccttacaag aggcagagac tgaccggagg tccttccgtc tggatcctgt gtctgggagg     1920

ttgagtacta tttcctcctt ggacagagaa gagcaagcct tctactccct gttggttctg     1980

gccacagatc tgggctcccc tccccagtca tcaatggctc gcataaatgt gagtcttctg     2040

gatataaatg ataacagccc tgtcttctac ccggtccaat actttgctca cattaaggag     2100

aatgagcctg gaggtagcta catcaccact gtgtctgcca ctgacccaga cttgggtacc     2160

aatggtactg tcaaatatag catatctgct ggggacaggt ctcggtttca ggtcaatgct     2220

cagagtgggg ttatttctac aagaatggcc ctagacagag aagaaaaaac agcttatcag     2280

ttgcaaatag tagctactga tggtggcaat ttacaatctc ccaaccaggc aatagtaacc     2340

atcactgtat tggacactca agacaaccca cctgtattca gtcaggttgc ctacagcttt     2400

gtggtttttg agaacgtggc gctgggatat catgtgggta gtgtgtctgc atccaccatg     2460

gatctcaatt ccaacatcag ttatctcatt actactgggg atcagaaagg tatgtttgct     2520

atcaaccagg tcactgggca gcttaccaca gcaaatgtga ttgatagaga agagcaatcc     2580

ttttatcagc tgaaggtagt ggccagtggg ggcacagtga ctggagacac tatggttaac     2640

ataacagtta aggatttgaa tgacaactct ccccatttcc ttcaggcaat agagagtgta     2700

aatgtggtgg agaattggca ggcaggtcac agcattttcc aggccaaagc tgtggaccct     2760

gatgaaggtg tcaatggcat ggtactctat agtctgaagc aaaaccccaa gaacctgttt     2820

gctatcaatg aaaagaatgg cactattagt ctgcttgggc ccctggatgt tcatgctggc     2880

tcctaccaaa tagagatctt ggcatctgac atgggtgtcc cacagctctc ctctagtgtc     2940

atcttaacag tttatgtcca tgatgtaaat gacaattcac cagtgtttga ccaactctct     3000

tatgaagtca ccctttctga gtcagaacct gtgaattctc gattctttaa agtacaagct     3060

tctgataagg attcaggagc aaatggtgaa attgcataca ccattgctga aggaaataca     3120

ggggatgctt ttggcatatt cccagatggt caattgtata taaaaagtga actggaccgt     3180

gaacttcaag acagatatgt tttaatggtt gttgcttctg acagagcagt ggaacccctt     3240

agtgctactg tgaatgttac tgtaatttta gaagatgtaa atgataacag acctcttttt     3300

aacagtacca attacacatt ttacttcgaa gaagagcaga gggctgggtc gtttgtgggc     3360

aaagtaagtg ctgtagataa agactttggg ccaaatggag aagtaaggta ttcttttgaa     3420

atggtgcagc cagattttga gttgcatgcc atcagtgggg aaattacaaa tactcatcag     3480

tttgacaggg agtctcttat gaggcggaga gggactgctg tgtttagctt tacagtcata     3540

gcaacagatc aggggatccc tcagcctctc aaggatcagg ccactgtaca tgtttacatg     3600

aaggatataa atgataatgc tcccaaattt ttaaaagact tttaccaagc tacaatatca     3660

gaatcagcag ccaatctgac acaagtgtta agagtatctg cctcagatgt tgatgaaggt     3720

aataatggac ttattcacta ttctataata aaaggaaatg aagaaagaca gtttgctata     3780

gacagtacct ctggtcaggt aacactaatt ggcaaattag actatgaagc aacacctgcc     3840

tattcccttg taattcaagc agtggattca gggacaatcc ccctcaattc aacgtgtact     3900

ttaaatattg atattttaga tgaaaatgac aatacccctt ctttccctaa atcaacactc     3960

tttgttgatg ttttggaaaa catgagaatt ggtgaactcg tgtcctctgt tactgcaact     4020

gattccgatt caggtgacaa tgctgattta tattacagta ttactgggac taacaaccac     4080

ggaactttta gcattagccc aaacactggg agtatttttc ttgccaaaaa actggacttt     4140

gaaacacagt ctttgtataa attaaatata acagcaaaag accaaggaag acctcctcgt     4200

tcatctacaa tgtcagtggt tattcacgtg agggacttta atgacaatcc tcctagcttt     4260

cctcctggag atattttcaa gtctattgtt gagaacattc ccatcggtac atctgtcatt     4320

tcagtgactg cacatgaccc tgatgcagac attaatggtc aactatccta cacaatcatt     4380

caacagatgc caagaggcaa ccactttacc atagatgaag tcaaagggac tatatatact     4440

aatgctgaaa tagatcggga atttgctaat ctctttgagt tgactgtaaa agccaatgat     4500

caagctgtgc caatagaaac tagacggtat gctttgaaga acgtgaccat tttggttaca     4560

gacctcaatg acaatgtccc aatgtttata tcacaaaacg cccttgctgc agacccatca     4620

gctgtgattg gttccgttct gacaacaatt atggctgctg acccagatga aggtgctaat     4680

ggagaaatag agtatgagat catcaatggg gacacagaca ccttcattgt tgatcgttat     4740

agtggagacc tgagagtggc ttcagcgttg gtgccttcac agttgatcta caatctcata     4800

gtttcagcaa cagaccttgg gcctgaaagg aggaaatcga ccactgaatt gaccatcatt     4860

cttcagggcc ttgatggacc tgtttttact caacccaaat atataactat tttgaaggaa     4920

ggagaaccca ttggcacaaa cgtgatatca atagaagcag ctagccccag aggatctgag     4980

gccccagtgg agtattatat tgtttcagtt cgttgtgaag aaaaaactgt tggacgcctc     5040

tttactattg gacgacatac tggtataatt cagaccgcag ccattctgga ccgggagcaa     5100

ggagcatgtc tttacctggt ggatgtttat gccatagaaa aatcaactgc ttttcccaga     5160

acacagagag cagaggtaga aataacactt caggatatca atgacaatcc accagtattt     5220

ccaacggaca tgctggatct cacggtagag gagaacattg gagatggctc taagattatg     5280

cagctgacag ccatggatgc tgatgagggt gcaaatgctc tcgtcacata cactatcatt     5340

agtggagctg atgatagttt tcgcatcgac ccagaatccg gagatctgat agcaaccagg     5400

cggttggaca gggaacgccg ctccaaatat tcactgctag ttcgtgctga tgatggtctt     5460

cagtcctcgg atatgagaat taatatcact gtcagtgatg tgaatgacca tacacccaaa     5520

ttttccagac ccgtgtactc ttttgacatt cctgaggaca caatccctgg ttctttggta     5580

gcagccattt tagccacgga tgatgactct ggtgtgaatg gagaaattac atatattgtg     5640

aatgaagatg atgaagatgg catctttttc ctgaatccta ttactggggt ctttaatttg     5700

actcgattat tagattatga agtacagcaa tattatatcc tcactgttcg agcagaagat     5760

ggtgggggac aatttactac catcagagtt tatttcaata ttctagatgt aaatgataat     5820

ccacctattt tcagcttgaa ttcatacagc acatctttaa tggagaatct acctgtggga     5880

tctactgttc ttgtgtttaa tgttactgat gcagatgatg gcatcaactc tcaattgact     5940

tatagcattg cttcaggtga tagccttggg cagtttactg ttgacaagaa tggtgtactc     6000

aaagtcctaa aagctttgga tcgggaaagt cagtccttct acaacttggt tgttcaagtg     6060

catgacctgc cacagattcc agcctccaga ttcacaagca ctgctcaagt ctccattatt     6120

ttgttggatg taaatgataa cccaccgaca tttctttccc ctaaattgac atacattcca     6180

gaaaatacac ctattgatac tgttgttttc aaagctcaag caactgaccc agatagtggc     6240

ccaaacagct atattgagta cactctgctg aaccctttgg gaaacaagtt cagtattggg     6300

accattgatg gtgaagtgag gctcactgga gaactggaca gagaagaagt ttctaattat     6360

actctaacag tggtggctac agacaaaggt caaccatctc tctcttcatc tacagaggtt     6420

gtagttatgg tacttgacat caatgataac aaccccatct ttgcacaagc tttgtataaa     6480

gtggagatta atgaaaacac acttactgga acagatataa tacaagtgtt cgcagcagat     6540

ggagatgaag gcacaaatgg acaggttcgc tatggcattg ttaatggtaa taccaatcag     6600

gaatttcgga tagactctgt cacaggtgcc atcactgtcg ctaaaccttt ggatagagaa     6660

aagaccccta cctaccattt aactgttcag gcaacagatc gaggcagcac acccagaact     6720

gatacctcca cggtcagcat tgttctactg gatattaatg actttgttcc tgtatttgag     6780

ctatctccat attctgtaaa tgtccctgag aatttaggga cactacccag aacaattctt     6840

caggtggtgg caagagatga tgatcgagga tctaacagca aactctcata tgttctgttt     6900

ggtggtaatg aagacaatgc ttttactctc tcagccagtg gagaacttgg agtaacacag     6960

agtctggatc gggaaacaaa agagcgcttt gtcttaatga ttacagctac agattcagga     7020

tcccctgcct tgactggaac tggaacaatc aacgtcatag tagatgatgt caatgacaat     7080

gtccccacat ttgccagtaa agcgtatttc acaacaattc ctgaggatgc accaactgga     7140

acagatgttt tattggtaaa tgcctcagat gctgatgctt caaagaatgc agttataagg     7200

atcatcggtg gaaactctca gttcacgatc aacccatcga caggacaaat catcaccagc     7260

gcattgttag atagggaaac aaaagataat tatactttgg tagtggtctg cagtgatgcg     7320

ggatccccag agcctctttc cagttccacc agtgtgcttg tcactgtgac tgatgtcaat     7380

gacaatccac caagatttca gcatcaccca tatgtcactc acatcccatc tcctactctt     7440

ccaggttcct ttgtctttgc ggttacagtc acagatgctg atattggacc aaattctgaa     7500

ctgcattatt ctctttcggg tagaaattct gaaaaatttc acattgaccc actgagggga     7560

gccattatgg ccgccggacc actaaacgga gcttcagaag tgacattttc tgtgcatgta     7620

aaagatggtg gctcatttcc aaagacagat tctacaacag tgactgttag attcgtgaat     7680

aaggccgatt tccctaaagt gagagccaaa gaacaaacgt tcatgtttcc tgaaaaccaa     7740

ccagtcagct ctcttgtcac caccatcaca ggatcctctt taagaggaga acctatgtca     7800

tattatatcg caagtgggaa tcttggcaat actttccaga ttgatcagtt aacagggcag     7860

gtgtctatta gtcaacctct ggattttgaa aagatacaaa aatatgttgt atggatagag     7920

gccagagacg gtggtttccc tcctttctcc tcttacgaga aacttgatat aacagtatta     7980

gatgtcaatg ataatgcccc aatttttaag gaagacccat ttatatctga aatattggaa     8040

aacctttccc ctcgaaaaat acttactgtt tcggcaatgg acaaggacag tggacccaat     8100

ggacagttag attatgaaat tgttaatggc aacatggaaa atagtttcag tatcaatcat     8160

gctactggtg aaattagaag cgttagacct ttggacaggg aaaaagtatc tcattatgtc     8220

ctaaccataa aatcatcaga caaagggtcc ccgtctcaga gtacttcagt aaaagtcatg     8280

attaacattt tagatgaaaa tgataatgcc cctaggtttt ctcagatatt tagtgcccat     8340

gttcctgaaa attccccctt aggatacaca gttacccgtg tcacaacttc tgatgaagac     8400

attgggatca atgcaattag tagatattct ataatggatg caagtcttcc atttacaatt     8460

aatcccagca caggggatat tgtcataagc agacctttaa atagggaaga tacagaccgt     8520

tacagaattc gagtttccgc acatgattct gggtggactg taagtacaga tgtcacaata     8580

tttgtgacag acatcaatga caatgctcca agatttagca gaacttccta ttatttagat     8640

tgccctgaac ttactgagat tggctccaaa gtaactcagg tatttgcaac agatcctgat     8700

gagggatcaa atggacaagt gttttatttc ataaaatccc aatcagaata tttcaggatt     8760

aatgccacca ctggagagat tttcaataaa cagatcttaa aataccaaaa tgtcactggc     8820

ttcagtaatg tgaatatcaa caggcatagt tttatagtga catcttcaga tcgaggtaaa     8880

ccttccttaa ttagtgagac aacagttacc atcaatatag tggacagtaa tgacaatgca     8940

cctcaatttc ttaaaagtaa atatttcact ccagtcacca aaaatgttaa ggttggtacg     9000

aagttaatca gagttacagc aatagatgac aaagattttg gactgaattc agaagtggag     9060

tatttcattt ctaatgataa ccatttagga aaatttaagt tggacaatga tacggggtgg     9120

atttcagtag catcctccct gatttctgac ttgaaccaaa acttttttat cacagtcact     9180

gcaaaggata agggaaaccc tccactttct tcccaagcaa ctgttcacat aactgtcact     9240

gaggaaaact accatacacc tgaattctct caaagccaca tgagtgcaac catccctgag     9300

agccatagca ttgggtccat tgtcagaact gtttctgcaa gagatagaga tgcagcgatg     9360

aatggcttga ttaagtacag catttcttca ggaaatgaag aaggcatttt tgcaatcaat     9420

tcttctacag gtatattaac actagccaaa gctcttgatt atgagctatg ccagaaacac     9480

gaaatgacga ttagtgctat agatggagga tgggttgcaa gaactggtta ctgcagtgtg     9540

accgtaaatg tgattgatgt gaatgataat tctccagtat tcctctctga tgactatttc     9600

cctactgttt tggaaaatgc cccaagtgga acaacagtta tccacctaaa tgcaacagat     9660

gctgactctg gaacaaatgc tgtgattgcg tatactgtac agtcatctga cagtgacctc     9720

tttgtcattg accctaacac aggagtcata accactcaag gcttcttgga ttttgaaacc     9780

aagcagagct accatcttac tgtgaaagcc ttcaatgtcc ccgatgagga aaggtgtagc     9840

tttgccactg ttaatataca attaaaaggg acaaatgaat atgtgccccg ttttgtttcc     9900

aaactttact attttgaaat ctcagaagca gctcctaaag gtactattgt tggagaagtg     9960

tttgctagcg accgtgattt gggcactgat ggggaggtac actatttgat ttttggtaat    10020

agtcgaaaga agggtttcca gatcaataag aagactggac agatttatgt ttctggaatt    10080

cttgatcgag aaaaagaaga aagggtgtct ttgaaggtat tggccaagaa ctttggcagc    10140

attagaggtg cagatataga tgaggtcact gtaaatgtca ccgtgcttga tgcaaatgac    10200

ccacccattt ttactctaaa catctacagt gtgcagatca gtgaaggggt cccaatagga    10260

actcatgtga cctttgtcag tgcctttgac tcagactcca tccccagctg gagcaggttt    10320

tcttacttca tcggatcagg gaatgaaaat ggtgcctttt ctattaatcc gcagacagga    10380

cagatcaccg ttactgcaga attagatcga gaaacccttc ccatctataa tctctcagtt    10440

ttggctgttg attcagggac cccctcagct acaggtagtg cctctttatt agtcaccctg    10500

gaagatataa atgataacgg gcccatgctg actgtcagtg aaggagaagt catggaaaac    10560

aaacggccag gcactttggt gatgaccctt cagtccactg accctgatct ccctccaaat    10620

caaggtccct ttacttatta cttgctgagc acaggtcctg ccaccagtta tttcagtctg    10680

agcactgctg gagttctgag cacaaccaga gagattgaca gagagcagat tgcagacttc    10740

tatctgtctg tggttaccaa ggattctggt gttcctcaaa tgtcttccac aggaactgtg    10800

catatcacag ttatagacca aaatgacaat ccttcacagt ctcggacggt ggagatattt    10860

gttaattatt atggtaactt gtttcccggt gggattttag gctctgtgaa gccacaggat    10920

ccagatgtgt tagacagctt ccactgctcc cttacttcag gagttaccag cctcttcagt    10980

attccagggg gtacttgtga tctgaattcc cagccaaggt ccacagatgg cacgtttgat    11040

ctgactgtcc ttagcaatga tggagttcac agcacagtca cgagcaacat ccgagttttc    11100

tttgctggat tttccaatgc cacagtggat aacagcatct tacttcgtct cggcgtacca    11160

acagtaaagg acttcttgac caaccactat cttcattttt tacgcattgc cagctcacag    11220

ctgacaggct tagggactgc tgtgcaactg tacagtgcat atgaagagaa caatagaacg    11280

tttcttttgg cagctgtgaa gcgaaatcat aatcagtatg tgaatcccag tggcgtagcc    11340

accttctttg aaagcatcaa agagatcctt ctccggcaga gtggagtaaa ggtggaatct    11400

gtggatcatg actcctgtgt gcatggccca tgtcagaatg gagggagctg tctacgaaga    11460

ttggctgtga gctccgtatt aaaaagccgt gagagtcttc cagtcatcat cgtggcaaat    11520

gaacctctgc agcctttctt atgcaagtgt ctgccaggat atgcgggtag ctggtgtgaa    11580

atagatatag atgaatgtct tccatcacct tgccacagtg gtggaacctg tcacaattta    11640

gtgggaggat tttcatgcag ctgcccagat ggcttcactg gtagggcgtg tgagagagat    11700

atcaatgagt gcctgcagag tccttgcaag aatggtgcca tctgccagaa ttttccagga    11760

agcttcaact gtgtttgcaa aactggatac acagggaaaa tgtgtgaatc ttcagtcaat    11820

tactgtgaat gcaacccctg ctttaatggt ggttcctgcc aaagtggtgt ggattcttat    11880

tattgtcatt gtccatttgg tgtctttgga aaacactgcg agttgaacag ttatggattt    11940

gaggagttat catacatgga atttccaagc ttggacccca ataacaacta tatttatgtc    12000

aaatttgcca cgattaaaag tcatgcctta ttgctttaca actatgacaa ccagacaggc    12060

gaccgggctg agtttttggc ccttgaaatt gccgaagaaa gactaagatt ctcttataat    12120

ttaggcagtg gtacatataa gctcaccacc atgaagaagg tgtcagatgg acattttcac    12180

actgtgattg ccaggagagc aggaatggca gcctccttaa ctgtggactc ctgttctgag    12240

aaccaagagc caggatattg tactgtcagt aatgtggcag tttcagatga ctggactctt    12300

gatgttcagc caaatagagt tacagttgga ggtatcagat ctctagaacc aatccttcag    12360

agaagaggac acgtggaaag ccatgatttt gttgggtgta taatggagtt tgcagtcaat    12420

ggaaggcctc tggaacccag ccaagctttg gcagcacaag gcatcctaga tcaatgccct    12480

aggctggaag gcgcttgtac tcgcagccca tgccaacatg gtggcacatg tatggattac    12540

tggtcatggc agcagtgtca ttgcaaagag ggactcactg ggaaatactg tgaaaaatct    12600

gttactcctg acactgcctt atcattagaa ggcaaagggc gcttggacta ccacatgagt    12660

cagaatgaga agcgggaata tttgttaagg caaagcttac gaggtgccat gttggagcct    12720

tttggtgtga acagtctgga agtaaaattt aggaccagaa gcgagaatgg cgttttaatc    12780

catatccaag aaagcagcaa ttacactact gtgaagatta agaatggcaa agtatatttt    12840

acatccgatg caggaattgc tgggaaagtg gagagaaata ttcctgaagt atatgttgca    12900

gacggccact ggcacacttt tctaattggg aaaaatggaa cagcaacagt attgtctgtt    12960

gacagaatat ataacagaga tattatccac cctactcagg acttcggtgg ccttgatgtg    13020

cttactatat cacttggagg aattccaccc aatcaagcac atcgagatgc ccaaacagca    13080

ggttttgatg gctgcattgc ttctatgtgg tatggtggag aaagtcttcc tttcagcggg    13140

aagcatagct tggcctccat ctcaaaaaca gatccctcag tgaagattgg ctgccgtggc    13200

ccgaacattt gtgccagcaa cccctgctgg ggtgatttgc tgtgcattaa tcagtggtat    13260

gcctacaggt gtgtccctcc tggggactgt gcctcccacc cgtgccagaa tggtggcagc    13320

tgtgagccag gcctgcactc cggcttcacc tgtagctgcc cagactcgca cacgggaagg    13380

acctgtgaga tggtggtggc ctgtcttggc gtcctctgtc ctcaggggaa ggtgtgcaaa    13440

gctggaagtc ctgcggggca tgtctgtgtt ctgagtcagg gccctgaaga gatctctctg    13500

cctttgtggg ctgtgcctgc catcgtgggc agctgcgcaa ccgtcttggc cctcctggtc    13560

cttagcctga tcctgtgtaa ccagtgcagg gggaagaagg ccaaaaatcc caaagaggag    13620

aagaaaccga aggagaagaa gaaaaaggga agtgagaacg ttgcttttga tgaccctgac    13680

aatatccctc cctatgggga tgacatgact gtgaggaagc agcctgaagg gaacccaaaa    13740

ccagatatca ttgaaaggga aaacccctac cttatctatg atgaaactga tattcctcac    13800

aactcagaaa ccatccccag cgcccctttg gcatctccag agcaggagat agagcactat    13860

gacattgaca acgccagcag catcgcccct tcggatgcag acatcattca acactacaag    13920

cagttccgca gccacacacc aaaattttca atccagaggc acagtcccct aggctttgca    13980

aggcaatccc ccatgccctt aggagcaagc agtttgactt accagccttc atatggtcaa    14040

ggtttgagaa ccagctccct aagccactca gcatgcccaa ctcccaaccc tctgtctcga    14100

cacagtccag cccctttctc caaatcttct acgttctata gaaacagccc agcaagggaa    14160

ttgcatcttc ctataaggga tggtaatact ttggaaatgc atggtgacac ctgccaacct    14220

ggcattttca actatgccac aaggctggga aggagaagca agagtcctca ggccatggca    14280

tcacatggtt ctagaccagg gagtcgccta aagcagccga ttgggcagat tccactggaa    14340

tcttctcctc cagtcggact ttctattgaa gaagtggaga ggctcaacac acctcgccct    14400

agaaacccaa gtatctgcag tgcagaccat gggaggtctt cttcagagga ggactgcaga    14460

aggccactgt ctagaacaag gaatccagcg gatggcattc cagctccaga atcctcttct    14520

gatagtgact cccatgaatc tttcacttgc tcagaaatgg aatatgacag ggagaagcca    14580

atggtatata cttccagaat gcccaaatta tctcaagtca atgaatctga tgcagatgat    14640

gaagataatt atggagccag actgaagcct cgaaggtacc acggtcgcag ggccgaggga    14700

ggacctgtgg gcacccaggc agcagcacca ggcactgctg acaacacact gcccatgaag    14760

ctagggcagc aagcagggac tttcaactgg gacaaccttt tgaactgggg ccctggcttt    14820

ggccattatg tagatgtttt taaagatttg gcatctcttc cagaaaaagc agcagcaaat    14880

gaagaaggca aagctgggac aactaaacca gtccccaaag atggggaagc agaacagtat    14940

gtgtgaagtt tatgtactgg cactataaaa tataaaaaca agaaataata ctcaaaccat    15000

tgtaaagttg ctgactaggt tgggtcacat ttgaaaaaca ggccagtatg gactagtggt    15060

ggagggaaaa ctttaaaaat aataaccaca atgctgctga aacagactca caacaactct    15120

taatttaaac atgtgtggtt gaatttattt ccctgcatgc attgtgtttt gtaactagtt    15180

atgtggcatg cagcatttgg aaaatttttc ttatttacca gtgtttgatt tgtgattttt    15240

aaaaattgat acctttacca ttgcagaaaa gaacttgtgc tttcccagtg gcgtatgtgt    15300

attgtttcaa ctgtattatt ataattatat tttgcattgc aagattcttg atgttaaacc    15360

aatccttgta aagtgtaaaa aggaaccctc ctatcgtgga atgaaagatt aagtatatta    15420

acacttttca gaatgatagt ttctgtattt gatgttgctc agaaatgtct gagtatttga    15480

gtaagtttta catgacagtg ggtactgaaa ttaagtcatt ttgttcagca ctttaacgct    15540

ttcttataga attgtcttaa aacttctgga tccttgagca aatgattata gtctcctgac    15600

tttcatgagg cttccattag gaacagaatg attgcatgtt gtccccagaa cactgccacc    15660

ttgctatgcg aatgatgttc tcagcagcac ttctaagaaa cactcttaaa agttatttat    15720

tgaaaatttt tcgtatgctt ttaatatttt aaagaattga cctaaggaaa gcttatgatt    15780

ggacttattt tccaaccaga taacatttac tctaagtacc cagtttttat aatttatatg    15840

aaatcagatt tcaacactta ctttgtcatt ttgtagatca ttttttttaa atactgtgta    15900

aaaacttttt ttacacctaa gctgtgtttt tgatactgat attttcctat gctgaatagt    15960

tttcttactt tcagggaagg taagaaaata ctttttttat atttgttact tatgtaacat    16020

tcatattttt ctcattttga tatttgtaac atactgtatg ctttctactt gtaaatgtca    16080

acaatagaat taaaatattt atttaaaata aaaa                                16114


<210>  257
<211>  10724
<212>  DNA
<213>  homo sapiens

<400>  257
ctttccaata tccgtcttcg gagcgcacgg gaatccgccg agctctgcgt gcaggccctt       60

ttttcttttg aggttcacat tttttgaaat tttacgccag ggcttttgta atttcctccc      120

ccgcccgctg acggtcctgg agtcgctcgg ggctttaggc cggttatgca acgtgtaccg      180

ctcggggctg ccggctgcac ctccgccgcg cctcgccgct cactgcgcta gacccggcgc      240

cccgcgtctc gcttcgcggg cagtcagggg gccggcgctc tgtcgaggtc tccagctaga      300

gcagggagcc cgagcccgag ggagtccccg gagccgacga agggcttatt agaccctgac      360

tcttttctga ggcgcgcaga ttttgtcttt gatcactccc tctccgcggg tctacggccg      420

cgcgctttcg gcgccggcga tggggagaag acggaggctg tgtctccagc tctacttcct      480

gtggctgggc tgtgtggtgc tctgggcgca gggcacggcc ggccagcctc agcctcctcc      540

gcccaagccg ccccggcccc agccgccgcc gcaacaggtt cggtccgcta cagcaggctc      600

tgaaggcggg tttctagcgc ccgagtatcg cgaggagggt gccgcagtgg ccagccgcgt      660

ccgccggcga ggacagcagg acgtgctccg agggcccaac gtgtgcggct ccagattcca      720

ctcctactgc tgccctggat ggaagacgct ccctggagga aaccagtgca ttgtcccgat      780

ttgtagaaat agttgtggag atggattttg ttcccgtcct aacatgtgta cttgttccag      840

tgggcaaata tcatcaacct gtggatcaaa atcaattcag cagtgcagtg tgagatgcat      900

gaatggtggg acctgtgcag atgaccactg ccagtgccag aaaggatata ttggaactta      960

ttgtggacaa cctgtctgtg aaaatggatg tcagaatggt ggacgttgca tcggacccaa     1020

ccgctgtgct tgtgtttatg ggttcactgg tccacagtgt gaaagagatt acaggacagg     1080

cccgtgtttc actcaggtca acaaccagat gtgccaaggg cagctgacag gcattgtctg     1140

cacgaagact ctgtgctgtg ccaccattgg acgggcgtgg ggccatccct gtgagatgtg     1200

tccagcccag cctcagccct gccgacgggg tttcatcccc aacatccgca ctggagcttg     1260

ccaagatgtt gatgaatgcc aggctatccc agggatatgc caaggaggaa actgtatcaa     1320

tacagtgggc tcttttgaat gcagatgccc tgctggtcac aaacagagtg aaactactca     1380

gaaatgtgaa gacattgatg agtgcagcat cattcctggg atatgtgaaa ctggtgaatg     1440

ttccaacacc gtgggaagct atttttgtgt ttgtccacgt ggatatgtaa cctcaacaga     1500

tggctctcga tgcatcgatc agagaacagg catgtgtttc tcgggcctgg tgaatggccg     1560

ctgtgcacaa gagctcccgg ggagaatgac gaaaatgcag tgctgctgtg agcctggccg     1620

ctgctggggc atcggaacca ttcctgaagc ctgtcctgtc agaggttctg aggaatatcg     1680

cagactttgc atggatggac ttccaatggg aggaattcca gggagtgctg gttccagacc     1740

tggaggcact gggggaaatg gctttgcccc aagtggcaat ggcaatggct atggcccagg     1800

agggacaggc ttcatcccca tccctggagg caatggcttt tctcctggcg ttgggggagc     1860

cggtgtgggg gccgggggac agggacctat catcactgga ctaacaattc tgaaccagac     1920

aatagatatc tgtaagcatc atgctaacct ttgtttaaat ggacgctgta taccaactgt     1980

ctcaagctac cgatgtgaat gcaacatggg ttataagcag gatgcaaatg gagattgtat     2040

agatgttgat gaatgcacat caaatccctg cactaatgga gattgtgtta acacacctgg     2100

ttcctattat tgtaaatgtc atgctggatt ccagaggact cctaccaagc aagcatgcat     2160

tgatattgat gagtgcatcc agaatggggt tctttgtaaa aacggtcgat gcgtgaacac     2220

agatggaagt ttccagtgca tttgcaatgc cggctttgaa ttaactacag atggaaaaaa     2280

ctgtgttgat catgatgaat gtacaactac caacatgtgt ttgaatggaa tgtgcatcaa     2340

tgaagatggc agcttcaagt gcatctgcaa accaggattt gtcttggctc caaatgggcg     2400

ttactgtact gatgttgatg aatgccagac cccaggaatc tgcatgaatg ggcactgcat     2460

caacagtgaa gggtccttcc gctgtgactg tcccccaggc ctggctgtgg gcatggatgg     2520

acgtgtgtgt gttgatactc acatgcgcag tacctgctat ggaggaatca agaaaggagt     2580

gtgtgtgcgt cctttccccg gtgcagtgac caagtccgaa tgctgctgtg ccaatccaga     2640

ctatggtttt ggagaaccct gccagccatg ccctgcaaaa aattcagctg aattccacgg     2700

cctttgtagt agtggagtag gtatcactgt ggatggaaga gatatcaatg aatgtgcttt     2760

ggatcctgat atatgtgcca atgggatttg tgaaaactta cgtggtagtt accgttgtaa     2820

ttgcaacagt ggctatgaac cagatgcctc tggaagaaac tgtattgaca ttgatgaatg     2880

tttagtaaac agactgcttt gtgataacgg attgtgccga aacacgccag gaagttacag     2940

ctgtacgtgc ccaccagggt atgtgttcag gactgagaca gagacctgtg aagatataaa     3000

tgaatgtgaa agcaacccat gtgtcaatgg ggcctgcaga aacaaccttg gatctttcaa     3060

ttgtgaatgt tcgcccggca gcaaactcag ctccacagga ttgatctgta ttgacagcct     3120

gaaggggacc tgttggctca acatccagga cagccgctgt gaggtgaata ttaatggagc     3180

cactctgaaa tctgaatgct gtgccaccct cggagccgcc tgggggagcc cctgtgagcg     3240

gtgtgaacta gatacagctt gcccaagagg gcttgccagg attaaaggtg ttacgtgtga     3300

agatgttaat gagtgtgagg tgttccctgg cgtttgtcca aatggacgct gtgtcaacag     3360

taagggatct tttcattgcg agtgccctga aggccttacg ttggatggga ctggccgtgt     3420

atgtttggat attcgcatgg agcagtgtta cttgaagtgg gatgaagatg aatgcatcca     3480

ccccgttcct ggaaagttcc gcatggatgc ctgctgctgt gctgtcgggg cggcttgggg     3540

caccgagtgt gaggagtgcc ccaaacctgg caccaaggaa tacgagacgc tgtgcccccg     3600

cggggctggc tttgctaacc gaggggatgt tcttactggg cggccatttt acaaagacat     3660

caatgaatgc aaagcatttc ctgggatgtg cacttatggg aagtgcagaa atacaatcgg     3720

aagcttcaaa tgccgttgca atagtggctt tgctctagac atggaggaaa gaaactgcac     3780

ggacatcgac gagtgcagga tttctcctga cctctgtggc agtggaatct gcgtcaatac     3840

accgggcagc tttgagtgcg agtgcttcga aggctatgaa agtggcttca tgatgatgaa     3900

gaactgcatg gacattgacg aatgtgaacg taaccctctc ctttgtaggg gtggcacctg     3960

tgtgaacact gagggcagct ttcagtgtga ctgcccactg ggacacgagc tgtcaccatc     4020

ccgtgaggac tgtgtggata ttaatgaatg ctccctgagt gacaatctct gcagaaatgg     4080

aaaatgtgtg aacatgattg gaacctatca gtgctcttgc aatcctggat atcaggctac     4140

gccagaccgc cagggctgta cagatattga tgaatgtatg ataatgaacg gaggctgtga     4200

cacccagtgc acaaattcag agggaagcta cgaatgcagc tgcagtgagg gttatgccct     4260

gatgccagat gggagatcgt gtgcagacat tgatgaatgt gaaaacaatc ctgatatctg     4320

tgatggcggc cagtgtacca acattcctgg agagtatcgc tgcctctgct atgatggctt     4380

catggcttcc atggacatga aaacatgcat tgatgtcaat gaatgtgacc taaattcaaa     4440

tatctgcatg tttggggaat gtgagaacac aaagggatcc ttcatttgcc actgtcagct     4500

gggttactca gtgaagaagg ggaccacagg atgtacagat gtggatgagt gtgaaattgg     4560

tgctcataac tgcgacatgc atgcctcatg tctgaatatc ccaggaagct tcaagtgtag     4620

ctgcagagaa ggctggattg gaaacggcat caagtgtatt gatctggacg aatgttctaa     4680

tggaacccac cagtgtagca tcaatgctca gtgtgtaaat accccgggct cataccgctg     4740

tgcctgctcc gaaggtttca ctggtgatgg ctttacctgc tcagatgttg atgagtgtgc     4800

agaaaacata aacctctgtg agaacggaca gtgccttaat gtcccgggtg catatcgctg     4860

cgagtgtgag atgggcttca ctccagcctc agacagcaga tcctgccaag atattgatga     4920

atgctccttc caaaacattt gtgtctttgg aacatgtaat aacctgcctg gaatgtttca     4980

ttgcatctgc gatgatggtt atgaattgga cagaacagga gggaactgta cagatattga     5040

tgagtgtgca gatcctataa actgtgtcaa tggcctatgt gtcaacacgc ctggtcgcta     5100

tgagtgtaac tgcccacccg attttcagtt gaacccaact ggtgtgggtt gtgttgacaa     5160

ccgtgtgggc aactgctacc tgaagtttgg acctcgagga gatgggagtc tgtcttgcaa     5220

caccgagatc ggggtgggcg tcagtcgctc ttcatgctgc tgctctctgg gaaaggcctg     5280

gggaaacccc tgtgagacat gcccccctgt caatagcact gaatattaca ccctgtgtcc     5340

cggaggtgaa ggcttcagac ctaaccccat cacaatcatt ttagaagaca ttgacgaatg     5400

ccaggagtta ccaggtctct gccagggtgg aaactgcatc aacacttttg ggagcttcca     5460

gtgtgagtgc ccacaaggct actacctcag cgaggatacc cgcatctgtg aagatattga     5520

tgagtgtttt gcacatcctg gtgtgtgtgg gcctgggacc tgctataaca ccctgggaaa     5580

ttacacctgc atttgcccac ctgagtacat gcaggtcaat ggaggccaca actgcatgga     5640

catgagaaaa agcttttgct accgaagcta taatggaacc acttgtgaga atgagttgcc     5700

tttcaatgtg acaaaaagga tgtgctgctg cacatataat gtgggcaaag cctggaacaa     5760

accttgtgaa ccatgcccaa ctccaggaac agctgacttt aaaaccatat gtggaaatat     5820

tcctggattc acctttgaca ttcacacagg aaaagctgtt gacattgatg aatgtaaaga     5880

gattccaggc atttgtgcaa atggtgtgtg cattaaccag attggcagtt tccgctgtga     5940

atgccctaca ggattcagtt acaatgacct gctgttggtt tgtgaagata tagatgagtg     6000

cagcaatggt gataatctct gccagcggaa tgcagactgc atcaatagtc ctggtagtta     6060

ccgctgtgaa tgtgccgcgg gtttcaaact ttcacccaat ggggcctgtg tagatcgcaa     6120

tgaatgttta gaaattccta acgtttgcag tcatggcttg tgtgttgatc tgcaaggaag     6180

ttaccagtgc atctgccaca atggctttaa ggcttctcag gaccagacca tgtgcatgga     6240

tgttgatgag tgcgagcggc atccatgtgg aaatggaact tgtaaaaaca ccgttggatc     6300

ctataactgt ctgtgctacc cagggtttga actcactcat aataatgatt gcctggacat     6360

agatgagtgc agttcctttt ttggtcaggt gtgcagaaat ggacgttgtt ttaatgaaat     6420

tggttctttc aagtgtctat gtaacgaagg ttatgaactt accccagatg gcaaaaactg     6480

tatagacact aatgagtgtg tcgcccttcc cggctcttgc tctcctggta cctgtcagaa     6540

tttggaggga tccttcagat gcatctgtcc cccagggtat gaagtaaaaa gcgagaactg     6600

cattgatata aatgaatgtg atgaagatcc caacatttgt ctttttggtt cctgtactaa     6660

tactccaggg ggcttccagt gcctctgccc ccctggcttt gtactatctg ataatggacg     6720

gagatgcttt gatactcgcc agagcttctg cttcacaaat tttgaaaatg gaaagtgttc     6780

tgtacccaaa gctttcaaca ccacaaaagc aaaatgctgc tgtagtaaga tgccaggaga     6840

gggctggggg gacccctgtg agctgtgccc caaagacgat gaagttgcat ttcaggattt     6900

gtgtccatat ggccatggaa ctgtccctag tcttcatgat acacgtgaag atgtcaatga     6960

gtgtcttgag agcccaggca tttgttcaaa tggtcaatgt atcaacaccg acggatcttt     7020

tcgctgtgaa tgtccaatgg gctacaacct tgactacact ggagtacgct gtgtggatac     7080

tgatgagtgt tcaatcggca atccgtgtgg aaatggtaca tgcaccaatg ttattgggag     7140

ttttgaatgc aattgcaatg aaggctttga gccagggccc atgatgaatt gtgaagatat     7200

caacgaatgt gcccagaacc cactgctgtg tgctttccgc tgcatgaaca cttttgggtc     7260

ctatgaatgc acgtgcccga ttggctatgc cctcagggaa gatcaaaaga tgtgcaaaga     7320

tctggatgaa tgtgctgaag ggttacacga ctgtgaatct aggggcatga tgtgtaagaa     7380

tctaatcggc accttcatgt gcatctgccc tcctggaatg gcccgaaggc ccgatggaga     7440

aggctgtgta gatgaaaatg aatgcaggac caagccagga atctgtgaaa atggacgttg     7500

tgttaacatt attggaagct atagatgtga gtgtaatgaa ggattccagt caagttcttc     7560

aggcactgaa tgccttgaca atcgacaggg tctctgcttt gcagaggtac tgcagacaat     7620

atgtcaaatg gcatccagta gtcgcaatct cgtcactaag tcagaatgct gctgtgatgg     7680

tgggcgaggc tggggccacc agtgcgagct ttgcccactt cctggaactg cccagtacaa     7740

aaagatatgt cctcatggcc caggatatac aactgatgga agagatattg atgaatgtaa     7800

ggtaatgcca aacctctgca ccaatggtca gtgcatcaat accatgggct cattccgatg     7860

cttctgcaag gttggctaca ccacagacat cagtggaacc tcttgtatag accttgatga     7920

atgctcccag tccccgaaac catgcaacta catctgcaag aacactgagg ggagttatca     7980

gtgttcatgt ccgagggggt atgtcctgca agaggatgga aagacatgca aagaccttga     8040

tgaatgtcaa acaaagcagc ataactgcca gttcctctgt gtcaacaccc tgggggggtt     8100

tacctgtaaa tgtccacctg gtttcacaca gcatcacact gcttgtatcg acaacaacga     8160

atgtgggtct caaccttcgc tttgtggagc aaagggaatc tgtcaaaaca ctccaggcag     8220

tttcagctgt gaatgccaaa gagggttctc tcttgatgcc accggactga actgtgaaga     8280

tgttgatgaa tgtgatggga accacaggtg ccaacacggc tgccagaaca tcctgggtgg     8340

ctacagatgt ggctgccccc aaggctacat ccagcactac cagtggaatc agtgtgtcga     8400

tgagaatgaa tgctccaatc ccaatgcctg tggctctgct tcctgctaca acaccctggg     8460

gagttacaag tgcgcctgcc cctcggggtt ctccttcgac cagttctcca gtgcctgcca     8520

cgacgtgaat gagtgctcgt cctccaagaa cccctgcaat tacggctgct ctaacacgga     8580

ggggggctac ctctgtggct gcccccctgg gtattacaga gtgggacaag gccactgtgt     8640

ctcaggaatg ggatttaaca aggggcagta cctgtcactg gatacagagg tcgatgagga     8700

aaatgctctg tccccagaag catgctacga gtgcaaaatc aacggctatt ctaagaaaga     8760

cagcaggcag aagagaagta ttcatgaacc tgatcccact gctgttgaac agatcagcct     8820

agagagtgtc gacatggaca gccccgtcaa catgaagttc aacctctccc acctcggctc     8880

taaggagcac atcctggaac taaggcccgc catccagccc ctcaacaacc acatccgtta     8940

tgtcatctct caagggaacg atgacagcgt cttccgcatc caccaaagga atgggctcag     9000

ctacttgcac acggccaaga agaagctcat gcccggcaca tacacactgg aaatcactag     9060

catccctctc tacaagaaga aggagcttaa gaaactggaa gagagcaatg aggatgacta     9120

cctcctaggg gagcttgggg aggctctcag aatgaggctg cagattcagc tctattaacc     9180

cttcacagac ttgggcccag gctcaaatcc tagcacagcc agtctgcaga agcatttgaa     9240

aagtcaagga ctaattttaa agaggaaaaa taataataac tcttgtttct ttcctccctg     9300

tcttagactt tgaatgttga ccctcacagg gagggataat ttagactctg gtatggccaa     9360

agatttgagc acaaaggcaa ccgtggttac tgtatttttt atataacttc attttaaaat     9420

atattaaaag aaacctaaat gttcaagata tcagcatatg gcactaaatg cacaaaaata     9480

atgtgagctt tttttttttt tcctgttagc agtctgtaac actttgggta ttttgctata     9540

gttgctaatt aaaaaaatat agatgtttat ttatttttaa tgcagtaata tatggagaaa     9600

tgaacaaact atgtaaacaa aaagggaaac tcacttgttt ttctttagat ttataaattt     9660

gagctatttt ttttagaggt gctttttaaa aatccaatag atacaagaga tgtttccttt     9720

ggttttctgc cagtcatcca gctgatacac acctgatgat tttaaagaaa gccacacaga     9780

gctgaatggg cagtgtaatc aataatttaa aaaacatgaa tgtcattaga tcctttataa     9840

cgtagatcga agccaaagca gctcatttgt gacaacattt catatcacca gacacaccag     9900

gcaacagaag ttgaagcaca accactgtag caaaatacct tgactgcttg tgagaccatt     9960

agcattgcag gccaaaccgt actgtatttc cttctcataa cctcaaggaa ccatatgtgc    10020

tacccacaac acctcattct tacccagggt gcgctgcgtc ctcatggtac tgtaggcagc    10080

tgaagaaccg ccgttccctt gaaagggaac acctggcatt ctgtggtgtt tcgtgctgtc    10140

ttaaataatg gtgcatttat tatgttcaag ttatttcagg attgccatat gtgcaaacaa    10200

atcatgcaat gcagccaagg aatatatgtt gttgttgttg ttttaaaccc attttttttt    10260

tagaattttc attaatactg tagttataca ccatatgcct cattttatca tagcctattg    10320

tgtatgaaag atgtttgtac aatgaattga tgtttagttt gctttagtca tttaaaaaga    10380

tattgtacca ggatgtgcta ttaagagcac gtatccatta ttcttctcaa cccaagaacc    10440

tgtttcctgg accagtgacc aaacctcata tgtgaaatgg ccaaagcaca tgcaggctcc    10500

tggttgttcc tctcaaacct gtgctgacca aagattagta accagttata cccagtattt    10560

tgaggtttta ttgttttttt aataactaaa aagaaaaaag gaacagtgta aatttgtaat    10620

caagagtttg tgaggaaaaa cttatggttt ttggttttgt ttgtttttgt aggtctgtgt    10680

atcaaatatg acacttttct tgcaataaag cttattttgg ggta                     10724


<210>  258
<211>  4131
<212>  DNA
<213>  homo sapiens

<400>  258
ttttgtttgg ctgaggggag cgagcggcgc tttgggggag gggtcgcgta ggcgcctcac       60

ctgaccctgc ggccgtgcgg ttgctgctcc ggggcaggtc tccttccagg ccaggggccc      120

ggaatcatgt acataaagca ggtgattatc cagggttttc gaagttacag agatcaaaca      180

attgtagatc ccttcagttc aaaacataat gtgattgtgg gcagaaatgg atctggaaaa      240

agtaactttt tttatgcaat tcagtttgtt ctcagtgatg agtttagtca tcttcgtcca      300

gaacagcggt tggctttatt gcatgaaggt actggtcctc gtgttatttc tgcttttgtg      360

gagattattt ttgataattc agacaaccgg ttaccaatcg ataaagagga agtttcactt      420

cgaagagtta ttggtgccaa aaaggatcag tatttcttag acaagaagat ggtcacgaaa      480

aatgatgtga tgaacctcct tgaaagcgct ggtttttctc gaagcaatcc ttattatatt      540

gttaaacaag gaaagatcaa ccagatggca acagcaccag attctcagag attaaagcta      600

ttaagagaag tagctggtac tagagtgtat gacgaacgaa aggaagaaag catctcctta      660

atgaaagaaa cagagggcaa acgggaaaaa atcaatgagt tgttaaaata cattgaagag      720

agattacata ctctagagga agaaaaggaa gaactagctc agtatcagaa gtgggataaa      780

atgagacgag ccctggaata taccatttac aatcaggaac ttaacgagac tcgtgccaaa      840

cttgatgagc tttctgctaa gcgagagact agtggagaaa aatccagaca attaagagat      900

gctcagcagg atgcaagaga taaaatggag gatatcgaac gccaagttag agaattgaaa      960

acaaaaattt cagctatgaa agaagaaaaa gaacagctta gtgctgaaag acaagagcag     1020

attaagcaga ggactaagtt ggagcttaaa gccaaggatt tacaagatga actagcaggc     1080

aatagtgaac aaaggaaacg tttattaaaa gagaggcaga agctgcttga aaaaatagaa     1140

gaaaagcaga aagaactggc agaaacagaa cccaaattca acagtgtgaa agagaaagaa     1200

gaacgaggaa ttgctagatt ggctcaagct acccaggaaa gaacggatct ttatgcaaag     1260

cagggtcgag gaagccagtt tacatcaaaa gaagaaaggg ataagtggat taaaaaggaa     1320

ctcaagtctt tagatcaggc tattaatgac aagaaaagac agattgctgc tatacataag     1380

gatttggaag acactgaagc aaataaagag aaaaatctgg agcagtataa taaactggac     1440

caggatctta atgaagtcaa agctcgagta gaagaactgg acagaaaata ttacgaagta     1500

aaaaataaga aagatgaact acaaagtgaa agaaactact tgtggagaga agagaatgca     1560

gaacagcaag cacttgctgc taaaagagaa gatcttgaaa agaagcaaca acttcttaga     1620

gcagcaacag gaaaggccat tttaaatgga atagacagca taaacaaagt gctagaccac     1680

ttccgtcgaa aaggaataaa ccagcatgtt caaaatggct atcatggtat tgtaatgaat     1740

aactttgaat gtgaaccagc tttctacaca tgcgtggaag tcactgctgg aaacaggtta     1800

ttttatcaca ttgttgattc agatgaagtc agcacgaaga ttttaatgga gtttaataaa     1860

atgaatcttc ctggagaggt tacttttctg cctcttaaca agttagatgt cagggataca     1920

gcctatcctg aaaccaatga tgctattcct atgatcagca aactgaggta caatcccaga     1980

tttgacaaag ctttcaaaca tgtgtttgga aagactctta tttgtcgtag catggaagtt     2040

tcaacccagc tggcccgtgc tttcactatg gactgtatta ctttggaagg tgaccaagtc     2100

agccatcggg gtgctctaac tgggggttat tatgacacaa ggaagtctcg acttgaattg     2160

caaaaagatg ttagaaaagc agaagaagaa ctaggtgaac ttgaagcaaa gctcaatgaa     2220

aacctgcgca gaaatattga aaggattaat aatgaaattg atcagttgat gaaccaaatg     2280

caacagatcg agacccagca aaggaaattt aaagcatcta gagatagcat attatcagaa     2340

atgaagatgc taaaagagaa gaggcagcag tcagagaaaa ccttcatgcc taagcaacgt     2400

agcttacaga gtttggaggc aagcttgcat gctatggagt ctaccagaga gtcattgaaa     2460

gcagaactgg gaactgattt gctttctcaa ctgagtttgg aagatcagaa gagagtagat     2520

gcactgaatg atgagattcg tcaacttcag caggaaaaca gacagttgct aaatgaaaga     2580

attaaattag aaggtattat tactcgagta gagacttatc tcaatgagaa tctgagaaaa     2640

cgcttggacc aagtagaaca ggaacttaat gagctgagag agacagaagg gggtactgtt     2700

ctcacagcca caacatcaga acttgaagcc atcaataaaa gagtaaaaga cactatggca     2760

cgatcagaag atttggacaa ttccattgat aaaacagaag ctggaattaa ggagcttcag     2820

aagagtatgg agcgctggaa aaatatggaa aaagaacata tggatgctat aaatcatgat     2880

actaaagaac tggaaaagat gacaaatcgg caaggcatgc tattgaagaa gaaagaagag     2940

tgtatgaaga aaattcgaga acttggatca cttccccagg aagcatttga aaagtaccag     3000

acactgagcc tcaaacagtt gtttcgaaaa cttgagcagt gcaacacaga attaaagaag     3060

tacagccatg ttaacaaaaa ggctttggat cagtttgtaa atttctccga gcagaaagaa     3120

aagttaataa agcgtcaaga agagttagat aggggttaca aatcaatcat ggaactgatg     3180

aatgtacttg aacttcggaa atatgaagct attcagttaa ctttcaaaca ggtatctaag     3240

aacttcagtg aagtattcca gaagttagta cctggtggca aagctacttt ggtgatgaag     3300

aaaggagatg tggagggcag tcagtctcaa gatgaaggag aagggagtgg tgagagtgag     3360

aggggttctg gctcacaaag cagtgtccca tcagttgacc agtttactgg agttggaatt     3420

agggtgtcat ttacaggaaa acaaggtgaa atgagagaaa tgcaacagct ttcaggtgga     3480

cagaaatcct tggtagccct tgctctgatt tttgccattc agaaatgtga cccggctcca     3540

ttttacttgt ttgatgaaat tgaccaggct ctggatgctc agcacagaaa ggctgtgtca     3600

gatatgatta tggaacttgc tgtacatgct cagtttatta caactacttt taggcctgaa     3660

ctgcttgagt cagctgacaa attctatggt gtaaagttca gaaataaggt tagtcatatt     3720

gatgtgatca cagcagagat ggccaaagac tttgtagaag atgataccac acatggttaa     3780

ttggaaaata ctacctactg gtttgggaga tgtatatagt aatatgattc tcatacccag     3840

gaactgtaaa tttaaaccta aatatttggc caatagtttt cagacttaaa gcatcatagt     3900

ccttttatat ttgtctttgt attttataag atactctgta atgtcatgtt tgtactgata     3960

gtttaagaat ttaatttcct gtacaacttt ttgtaaaatg ttctgctcct attttaaatg     4020

ttttgaaaca tgctaaatat tctttcctaa ttattttatc acttatacta ccttttttat     4080

agcttcaatt aaataatcgg ttttatgact aaaaaaaaaa aaaaaaaaaa a              4131


<210>  259
<211>  2474
<212>  DNA
<213>  homo sapiens

<400>  259
aaaggcgggg cgggcggctg ccaagccggc caataggcgg ctctccggct gctaagccga       60

gagggcaggg gcgccgtcag tagcaccacc gccttccaag tttccccttg tggatgcgcg      120

gccccgcggc tctgctcctc ccggcgcaga ggggccggga gaggccacag gagcggacct      180

ggcacgggat ttctgaggaa cgggagaaga ctggcgcccg acccgctctg gagggtcggt      240

gaacgatgaa gggccggcgg cggcgacgcc gagagtactg caagttcgcg ctgctgttgg      300

tgctgtacac gctggtgctg ttgctcgtcc cctccgtatt ggacggcggc cgcgacgggg      360

acaagggcgc cgagcactgc cccggcctgc agcgcagcct gggagtgtgg agcctggagg      420

cggcggcggc cggcgaacgc gagcagggag cggaggcgcg ggccgccgag gaagggggcg      480

cgaaccagtc tcctcggttc ccaagcaacc tcagcggcgc tgtcggggag gcagtgtctc      540

gcgagaagca gcacatctac gtgcatgcca cctggcgcac cggctcgtcc ttcctgggcg      600

aactctttaa ccagcacccg gacgttttct acttgtatga gcccatgtgg catctatggc      660

aggcgctgta tccgggcgac gccgagagct tgcagggcgc gctgcgcgac atgctgcgtt      720

cgctcttccg ctgcgacttc tccgtgctgc ggctgtacgc gccgccgggg gaccccgctg      780

cgcgcgcccc ggacacggcc aatcttacca cggccgccct cttccgctgg cggactaaca      840

aggtcatctg ctcgccgcca ctgtgtcctg gcgcaccccg tgcccgggcc gaggtgggcc      900

tcgtcgagga caccgcctgc gagcgcagct gcccacccgt ggcgatacgc gccctggagg      960

ccgagtgccg aaagtacccg gtggtggtca tcaaggacgt gcgcctgctc gatctgggcg     1020

tgctggtgcc cctgttgcgt gatccaggcc tcaacctgaa ggtggtgcag cttttccgcg     1080

acccgagggc ggtgcacaac tcgcgcctca agtctaggca gggactgctg cgcgagagca     1140

tccaggtgct gcgcacccgc cagaggggcg accgcttcca ccgtgtgctg ctggcgcacg     1200

gcgtgggtgc tcgccccggg ggccagtctc gcgcgctgcc cgccgcgccg cgcgccgatt     1260

tcttcctgac cggtgcgctc gaggtgatct gcgaagcctg gctgcgcgat ctgcttttcg     1320

cgcgcggcgc gcccgcctgg ctgcggcgcc gctacctgag gctgcgctat gaggacctgg     1380

tgcggcagcc acgcgcccag ctgcgccgcc tgctgcgctt ctccgggcta cgcgcgctcg     1440

cagcgctcga tgccttcgcg ctcaacatga ctcgcggcgc ggcctacggc gccgaccggc     1500

ccttccacct gtcagcgcgc gacgcccggg aggcggtgca cgcctggcgc gagcgcctga     1560

gccgagagca ggtgcgccag gtggaggccg cctgcgctcc agccatgcgt ctgctcgcct     1620

accctcgcag cggagaggag ggcgacgcgg agcagcccag ggaaggggag acgccgctgg     1680

agatggatgc cgacggcgcc acgtagcctc ccatccctgt ccccggcacg gatccgggtc     1740

agtcaccacg aacaggggca ctcggcatgc tgccccagca ctggagaagc agcgctgtgg     1800

gggcaatctg tcacactctc agagtctggg acttgacttg ctaccaacaa ctgctgtgca     1860

attctgctga gcaggaatat catgagctgt tcaataatga cggacgcatt ggttgagatg     1920

aagtttccag taaggaagtg acagtgcaat gtggatattt atggctgtaa aataggaaga     1980

gctttagttc ccaggctgaa cctgccactg ctggagccat ttcaacaagg catcctcaca     2040

acaaagaaga gatgtgattt ggtaccattt cacaccagca ggtgtctgga cgaaaacatc     2100

aatgtgaata agggccaagt gcagtcctgt cttgattaaa ttacttaata atattattaa     2160

ataataatag gtctgggcag tattgttttt aacctgactc atccagctgt ccttcaaata     2220

gctccgtctc cctctaccca gaactgattt ttaaaaagaa gtaatttttc tccctgggct     2280

gggaaaaccc taatgaactg aaacacactt ttactttaaa atttttctgt ctggcgtttt     2340

tgtaatcata ctattaaatg actctggagt catgttaatg acaggatttg ttttgtttgg     2400

atgcagttca attgcatggt ttgggtaaaa gctagcctac atacaaagga atatgaagac     2460

tgtggaagaa actg                                                       2474


<210>  260
<211>  2863
<212>  DNA
<213>  homo sapiens

<400>  260
ggatgaggcc tcgccctcgc ctctttagta ggtcgggtga gtgtagtgtg cagggaagag       60

acgcgtcagc gccagggcca ggcccgcccg ggggcagccc ggcagccgaa tcttgggcta      120

ctctgtccca acagccggag cagatcagac cgaccggccc tgcccgctcg gtcccgcgcc      180

ctccagaccc tacggtctcc gtttctaggg gcacatggtt agcggcaggc gcccacagcc      240

aatccacttt gccagcctgc cccttcctct gccaagagca gcttcttcag ccgcgctcca      300

gttccgcaga cgcctgcccc accctgctct tcccttccag ggaagacgga tcacgcggcc      360

aagaacgaga ctcgcaaact gggcatttct ccgagccggg ctagagcaag tagcgagact      420

ccgcgtgaga gtgggaaaga gccttaacag gcaaccatgt tgcccagtgg gttttctgtg      480

cctttgggtg cggaccaatg aggcgcgtgg ggcgggactt ccgcttcgcc taggtgttgt      540

cgtccctgct agtactccgg gctgtggggg tcggtgcgga tattcagtca tgaaatcagg      600

gtagggactt ctcccgcagc gacgcggctg gcaagactgt ttgtgttgcg ggggccggac      660

ttcaaggtga ttttacaacg agatgctgct ctccataggg atgctcatgc tgtcagccac      720

acaagtctac accatcttga ctgtccagct ctttgcattc ttaaacctac tgcctgtaga      780

agcagacatt ttagcatata actttgaaaa tgcatctcag acatttgatg acctccctgc      840

aagatttggt tatagacttc cagctgaagg tttaaagggt tttttgatta actcaaaacc      900

agagaatgcc tgtgaaccca tagtgcctcc accagtaaaa gacaattcat ctggcacttt      960

catcgtgtta attagaagac ttgattgtaa ttttgatata aaggttttaa atgcacagag     1020

agcaggatac aaggcagcca tagttcacaa tgttgattct gatgacctca ttagcatggg     1080

atccaacgac attgaggtac taaagaaaat tgacattcca tctgtcttta ttggtgaatc     1140

atcagctaat tctctgaaag atgaattcac atatgaaaaa gggggccacc ttatcttagt     1200

tccagaattt agtcttcctt tggaatacta cctaattccc ttccttatca tagtgggcat     1260

ctgtctcatc ttgatagtca ttttcatgat cacaaaattt gtccaggata gacatagagc     1320

tagaagaaac agacttcgta aagatcaact taagaaactt cctgtacata aattcaagaa     1380

aggagatgag tatgatgtat gtgccatttg tttggatgag tatgaagatg gagacaaact     1440

cagaatcctt ccctgttccc atgcttatca ctgcaagtgt gtagaccctt ggctaactaa     1500

aaccaaaaaa acctgtccag tgtgcaagca aaaagttgtt ccttctcaag gcgattcaga     1560

ctctgacaca gacagtagtc aagaagaaaa tgaagtgaca gaacataccc ctttactgag     1620

acctttagct tctgtcagtg cccagtcatt tggggcttta tcggaatccc gctcacatca     1680

gaacatgaca gaatcttcag actatgagga agacgacaat gaagatactg acagtagtga     1740

tgcagaaaat gaaattaatg aacatgatgt cgtggtccag ttgcagccta atggtgaacg     1800

ggattacaac atagcaaata ctgtttgact ttcagaagat gattggttta tttcccttta     1860

aaatgattag gtatatactg taatttgatt ttttgctccc ttcaaagatt tctgtagaaa     1920

taacttattt tttagtattc tacagtttaa tcaaattact gaaacaggac ttttgatctg     1980

gtatttatct gccaagaata tacttcattc actaataata gactggtgct gtaactcaag     2040

catcaattca gctcttcttt tggaatgaaa gtatagccaa aacataaaaa aaaaaaaatc     2100

ctcagtatag cttgcaatta agacctagat cacagtattt aagtgttttg cgttttatac     2160

atgaggtcag tgctacagcc acctagcatg aactaaccca gcttccacct ccataaagtt     2220

acctagagtt gttgagttgg aatatgttct ggcatttacc tgacctgcca atcattaggg     2280

agaggcaaca aggtaattca gcctttcctc ctatcagcac aaagaaactc aaagctgttt     2340

tttccctttc tgttccaaag cagtcttatc ctgacaggag cggtctatac tagtgcagat     2400

ttcaacactt ttttttaacg ttttaattac tatagtgtta tgtagagatt tgattgagca     2460

gctaatgttt ctgaacttta cttactaatt ttcagtgtcc ttaagggttc tgtagtgtta     2520

tcaaagcaaa aagaaaatgc tgcataaaaa taccaaactt cagcaactgt taatactcag     2580

atcatatacc tcttaataaa tagcatctta tgctaattag ccctgctaaa ctatgtacag     2640

aggaaactgt tcaagtattg gatttgaaag taagtgactt atgtttaaca gaactaatga     2700

tgtattgaaa cactgtatta tgaaaagcta aattatacat cattgtaact atgtagaaag     2760

tgtagactaa tgtataatca aaatgctaag gatttttata tggccttgta tgaggggagt     2820

ttgaatgtta ataaacatgt tttccacttt aagatccagt aaa                       2863


<210>  261
<211>  1644
<212>  DNA
<213>  homo sapiens

<400>  261
gctcagcatt tggggacgct ctcagctctc ggcgcacggc ccaggttatc ttgtagcata       60

gcaacttcgg atttcactct acccggagag tttcccgctt ggttgaacac attggcctca      120

ggaagcttcc ttcaaaatgt ctactgttca cgaaatcctg tgcaagctca gcttggaggg      180

tgatcactct acacccccaa gtgcatatgg gtctgtcaaa gcctatacta actttgatgc      240

tgagcgggat gctttgaaca ttgaaacagc catcaagacc aaaggtgtgg atgaggtcac      300

cattgtcaac attttgacca accgcagcaa tgcacagaga caggatattg ccttcgccta      360

ccagagaagg accaaaaagg aacttgcatc agcactgaag tcagccttat ctggccacct      420

ggagacggtg attttgggcc tattgaagac acctgctcag tatgacgctt ctgagctaaa      480

agcttccatg aaggggctgg gaaccgacga ggactctctc attgagatca tctgctccag      540

aaccaaccag gagctgcagg aaattaacag agtctacaag gaaatgtaca agactgatct      600

ggagaaggac attatttcgg acacatctgg tgacttccgc aagctgatgg ttgccctggc      660

aaagggtaga agagcagagg atggctctgt cattgattat gaactgattg accaagatgc      720

tcgggatctc tatgacgctg gagtgaagag gaaaggaact gatgttccca agtggatcag      780

catcatgacc gagcggagcg tgccccacct ccagaaagta tttgataggt acaagagtta      840

cagcccttat gacatgttgg aaagcatcag gaaagaggtt aaaggagacc tggaaaatgc      900

tttcctgaac ctggttcagt gcattcagaa caagcccctg tattttgctg atcggctgta      960

tgactccatg aagggcaagg ggacgcgaga taaggtcctg atcagaatca tggtctcccg     1020

cagtgaagtg gacatgttga aaattaggtc tgaattcaag agaaagtacg gcaagtccct     1080

gtactattat atccagcaag acactaaggg cgactaccag aaagcgctgc tgtacctgtg     1140

tggtggagat gactgaagcc cgacacggcc tgagcgtcca gaaatggtgc tcaccatgct     1200

tccagctaac aggtctagaa aaccagcttg cgaataacag tccccgtggc catccctgtg     1260

agggtgacgt tagcattacc cccaacctca ttttagttgc ctaagcattg cctggccttc     1320

ctgtctagtc tctcctgtaa gccaaagaaa tgaacattcc aaggagttgg aagtgaagtc     1380

tatgatgtga aacactttgc ctcctgtgta ctgtgtcata aacagatgaa taaactgaat     1440

ttgtacttta gaaacacgta ctttgtggcc ctgctttcaa ctgaattgtt tgaaaattaa     1500

acgtgcttgg ggttcagctg gtgaggctgt ccctgtagga agaaagctct gggactgagc     1560

tgtacagtat ggttgcccct atccaagtgt cgctatttaa gttaaattta aatgaaataa     1620

aataaaataa aatcaaaaaa aaaa                                            1644


<210>  262
<211>  1595
<212>  DNA
<213>  homo sapiens

<400>  262
gcaggaccgt cattgacgcc atgagcgcgc tgctgcggct gctgcgcacg ggtgccccag       60

ccgctgcgtg cctgcggttg gggaccagtg cagggaccgg gtcgcgccgt gctatggccc      120

tgtaccacac tgaggagcgc ggccagccct gctcgcagaa ttaccgcctc ttctttaaga      180

atgtaactgg tcactacatt tccccctttc atgatattcc tctgaaggtg aactctaaag      240

aggaaaatgg cattcctatg aagaaagcac gaaatgatga atatgagaat ctgtttaata      300

tgattgtaga aatacctcgg tggacaaatg ctaaaatgga gattgccacc aaggagccaa      360

tgaatcccat taaacaatat gtaaaggatg gaaagctacg ctatgtggcg aatatcttcc      420

cttacaaggg ttatatatgg aattatggta ccctccctca gattctttct tgtggagaag      480

ttattcatgt gaagatcctt ggaattttgg ctcttattga tgaaggtgaa acagattgga      540

aattaattgc tatcaatgcg aatgatcctg aagcctcaaa gtttcatgat attgatgatg      600

ttaagaagtt caaaccgggt tacctggaag ctactcttaa ttggtttaga ttatataagg      660

taccagatgg aaaaccagaa aaccagtttg cttttaatgg agaattcaaa aacaaggctt      720

ttgctcttga agttattaaa tccactcatc aatgttggaa agcattgctt atgaagaagt      780

gtaatggagg agctataaat tgcacaaacg tgcagatatc tgatagccct ttccgttgca      840

ctcaagagga agcaagatca ttagttgaat cggtatcatc ttcaccaaat aaagaaagta      900

atgaagaaga gcaagtgtgg cacttccttg gcaagtgatt gaaacatctg aaattctgct      960

gtcaagattc ccatctctaa ggactccaag tgctagagac aagggggtct atgagcattt     1020

actgacttcc tgttaaaact tcattttttc aaactttttg agctatgcaa tatataaata     1080

aacagtaaga attttaaatt actctccttt ggacatttat tgatataaaa agaagatttt     1140

ggccaggcac ggtggctcat gcctgtaatt tcagcacttt gggaggccga ggtgggcaga     1200

tcacaaggtc aggagttcaa gaccagcctg gccagtatgt tgaaacccca tctctattaa     1260

aaatacaaaa attagccagg cgtggtggtg catgcctgta gacccagcta ctcaggaggc     1320

tgaggcagaa gaactgcttg agcccaggag gcagaggttg cagtgagcag agattgtgcc     1380

actgcactcc agcctaggcg acagagagag actccgtctc aaaaaaaaaa aaaagatttt     1440

gtttcatttc atagcacaaa tttagaggca ttgagttgac catttctagt ttctatacct     1500

gaaggaaccc attgatttta ccagttttta tttctgtaga ttggatgtaa aaatcacaga     1560

ttcaataaat taataaactt tgtgtaaaaa aaaaa                                1595


<210>  263
<211>  10022
<212>  DNA
<213>  homo sapiens

<400>  263
aattgctccg ggagagacac aggactggag ggcttgagga atgtggtggt ccctctcttc       60

gttgtttctg ccccctgagg ttgtgctttc tcagggatat gcactctgca cttccattcc      120

tgcagtgaaa ttaactcgag cttggcagct cgagaggaga atgtggccac tttccgaggc      180

tcagagtatc tgtgctacga cctgtctcag aacccgatcc agagcagcag tgatgaaatc      240

accctctcct ttaagacctg gcagcgtaac ggcctcatcc tgcacacggg caagtcggct      300

gactatgtca acctggctct gaaggatggt gcggtctcct tggtcattaa cctggggtcc      360

ggggcctttg aggccattgt ggagccagtg aatggaaaat tcaacgacaa cgcctggcat      420

gatgtcaaag tgacacgcaa cctccggcag gtgacaatct ctgtggatgg cattcttacc      480

acgacgggct acactcaaga ggactatacc atgctgggct cggacgactt cttctatgta      540

ggaggaagcc caagtaccgc tgacttgcct ggctcccctg tcagcaacaa cttcatgggc      600

tgccttaaag aggttgttta taagaataat gacatccgtc tggagctgtc tcgcctggcc      660

cggattgcgg acaccaagat gaaaatctat ggcgaagttg tgtttaagtg tgagaatgtg      720

gccacactgg accccatcaa ctttgagacc ccagaggctt acatcagctt gcccaagtgg      780

aacactaaac gtatgggctc catctccttt gacttccgca ccacagagcc caatggcctg      840

atcctcttca ctcatggaaa gccccaagag aggaaggatg ctcggagcca gaagaataca      900

aaagtagact tctttgccgt ggaactcctc gatggcaacc tgtacttgct gcttgacatg      960

ggctctggca ccatcaaagt gaaagccact cagaagaaag ccaatgatgg ggaatggtac     1020

catgtggaca ttcagcgaga tggcagatca ggtactatat cagtgaacag caggcgcacg     1080

ccattcaccg ccagtgggga gagcgagatc ctggacctgg aaggagacat gtacctggga     1140

gggctgccgg agaaccgtgc tggccttatt ctccccaccg agctgtggac tgccatgctc     1200

aactatggct acgtgggctg catccgcgac ctattcattg atgggcgcag caagaacatt     1260

cgacagctgg cagagatgca gaatgctgcg ggtgtcaagt cctcctgttc acggatgagt     1320

gccaagcagt gtgacagcta cccctgcaag aataatgctg tgtgcaagga cggctggaac     1380

cgcttcatct gcgactgcac cggcaccgga tactggggaa gaacctgcga aagggaggca     1440

tccatcctga gctatgatgg tagcatgtac atgaagatca tcatgcccat ggtcatgcat     1500

actgaggcag aggatgtgtc cttccgcttc atgtcccagc gagcttatgg gctgctggtg     1560

gctacgacct ccagggactc tgccgacacc ctgcgtctgg agctggatgg ggggcgtgtc     1620

aagctcatgg ttaacttaga ctgtatcagg ataaactgta actccagcaa aggaccagag     1680

accttgtatg cagggcagaa gctcaatgac aacgagtggc acaccgttcg ggtggtgcgg     1740

agaggaaaaa gccttaagtt aaccgtggat gatgatgtgg ctgagggtac aatggtggga     1800

gaccataccc gtttggagtt ccacaacatt gaaacgggaa tcatgactga gaaacgctac     1860

atctccgttg tcccctccag ctttattggc catctgcaga gcctcatgtt taatggcctt     1920

ctctacattg acttgtgcaa aaatggtgac attgattatt gtgagctgaa ggctcgtttt     1980

ggactgagga acatcatcgc tgaccctgtc acctttaaga ccaagagcag ctacctgagc     2040

cttgccactc ttcaggctta cacctccatg cacctcttct tccagttcaa gaccacctca     2100

ccagatggct tcattctctt caatagtggt gatggcaatg acttcattgc agtcgagctt     2160

gtcaaggggt atatacacta cgtttttgac ctcggaaacg gtcccaatgt gatcaaaggc     2220

aacagtgacc gccccctgaa tgacaaccag tggcacaatg tcgtcatcac tcgggacaat     2280

agtaacactc atagcctgaa agtggacacc aaagtggtca ctcaggttat caatggtgcc     2340

aaaaatctgg atttgaaagg tgatctctat atggctggtc tggcccaagg catgtacagc     2400

aacctcccaa agctcgtggc ctctcgagat ggctttcagg gctgtctagc atcagtggac     2460

ttgaatggac gcctgccaga cctcatcaat gatgctcttc atcggagcgg acagatcgag     2520

cgtggctgtg aaggacccag taccacctgc caggaagatt catgtgccaa ccagggggtc     2580

tgcatgcaac aatgggaggg cttcacctgt gattgttcta tgacctctta ttctggaaac     2640

cagtgcaatg atcctggcgc tacgtacatc tttgggaaaa gtggtgggct tatcctctac     2700

acctggccag ccaatgacag gcccagcacg cggtctgacc gccttgccgt gggcttcagc     2760

accactgtga aggatggcat cttggtccgc atcgacagtg ctccaggact tggtgacttc     2820

ctccagcttc acatagaaca ggggaaaatt ggagttgtct tcaacattgg cacagttgac     2880

atctccatca aagaggagag aacccctgta aatgacggca aataccatgt ggtacgcttc     2940

accaggaacg gcggcaacgc caccctgcag gtggacaact ggccagtgaa tgaacattat     3000

cctacaggcc ggcagttaac catcttcaac actcaggcgc aaatagccat tggtggaaag     3060

gacaaaggac gcctcttcca aggccaactc tctgggctct attatgatgg tttgaaagta     3120

ctgaacatgg cggctgagaa caaccccaat attaaaatca atggaagtgt tcggctggtt     3180

ggagaagtcc catcaatttt gggaacaaca cagacgacct ccatgccacc agaaatgtct     3240

actactgtca tggaaaccac tactacaatg gcgactacca caacccgtaa gaatcgctct     3300

acagccagca ttcagccaac atcagatgat cttgtttcat ctgctgaatg ttcaagtgat     3360

gatgaagact ttgttgaatg tgagccgagt acagcaaacc ccacggagcc gggaatcaga     3420

cgggttccgg gggcctcaga ggtgatccgg gagtcgagca gcacaacagg gatggtcgtc     3480

ggcattgtgg ctgctgccgc cctctgcatc ttgatcctcc tgtacgccat gtacaagtac     3540

aggaacaggg acgaggggtc ctatcaagtg gacgagacgc ggaactacat cagcaactcc     3600

gcccagagca acggcacgct catgaaggag aagcagcaga gctcgaagag cggccacaag     3660

aaacagaaaa acaaggacag ggagtattac gtgtaaacat gcgaacactg ctcacacgcg     3720

agttttcaca gttatttcta tccacgccta tgaatctttg gacggtgaga tctcacagat     3780

gtcagaactg ctggaactat gaaatggggt atataaccac gactctggtg gggaaaaccg     3840

ttttttaaag gacacacaca cacacagcga tgcatctctc tctaaagctc agccacggct     3900

gcggcaaggt cccagcggtc gctgggagac agaaggtttt gtgccctgct gtatcataaa     3960

gcacacactt agcgctctgg agccggacgg tggctccacc acttccgcag gcctggaaac     4020

ttccttctcc ggaggacctt ttactaaaag gtagaagact tcatggctta cttgttccat     4080

aactccaagt gagtctgtaa tgtttgtgaa gcttgactgt aaccatgttt tttctgttta     4140

attatgtaaa aaacaaaact acaacaacaa aaaaagaaaa aagttaaaaa agaaaaaaac     4200

accaaaaaac aaaaacaaac aaaaaaaaaa acccacaacc cttatctggt tctgaccagt     4260

gtgcgtgtaa ctttatgatc tgaggggaaa aatggctttt gggtttttgt ttattttttt     4320

gataatgact ggacatcaga agaggaaaaa aactcaaaac aaaagcgaga gagactattg     4380

ccatatgaac tcaaaagcta tcatggtgtt cactctacat atcaggttat ggtgtctcta     4440

gaatctgttg tttgtttcct ataagatgct ttgctgaaca catagcaaaa ttcatgtgac     4500

ggatgataaa ttgattcgaa aagctggtcc cccaggatct aatttcagaa tttaccaccc     4560

aaacccggaa cagatgggtt tagggctggt gttatcagag ctattggctt tacgtaacaa     4620

tattgttcct gtccattcac ccagccaaat tgtgttaaag aggaaagccc cacaaactaa     4680

aacagccttt cctagggaag aggaagggga ggtgggctgg atctgtgact gattgaaatg     4740

catgcaaata aaaaagacaa tattaaagtc tgttatcaaa ccagacagta ggggagttca     4800

actcgtgatg gaaccacaaa aggtcacaca agccaaccat gtcatgccag agtacaaaac     4860

acatagttct ttccccgccc cgaatgtgac aatggttttc atagtggttt aattttgtag     4920

cctgacattt atggataact ctgtccttcc atttgctcac ttctctcttc acccatcttt     4980

tttaaaaaca aataaatgaa taaagctgct gtgacacaca cacaaaagga atttaatagt     5040

ataatatata tataaataaa tatatataca gatatattta tcatggtatg tttgatggga     5100

tgactgacac aggaaatctg ttaaagtctt aaaatggaat gagaatgttg ttttaaaaga     5160

aaatagcaaa acaacaaaaa agcaaacctt aaaatgtgaa gaaagtgtga attttagttt     5220

tgtcacagtt aactgtgtca aagagaatta aaaaaaaaaa cttcagattt tgtttacata     5280

ttttactaca tttttgctgg tataattcct tagccaccta tgtacatact gctttaagaa     5340

atgttttttt cctgtttatt tctgtttggt ttatattctg gttgtctttt tctttttgta     5400

aagaggaaac aatgtacaga aaaacaataa actggttgta tggccatagc tatccgaaaa     5460

gcaagagaca aagcaagaca aatattcaca caaaaatgaa gtgtgtcctc tggagggtca     5520

gatatacaat ttcttttgta cagatgaaaa tcaatcagct gcttagattt agaaatctac     5580

tcttgctggt ctttgtaagt tgcatgaata tttgactttg aaaaaatatc ttaacgacat     5640

ggggcaaaaa gtgcaatcta aatggtagcc tttactaatg tgtgtggaaa gaggtgttcc     5700

tcattatcta atatttcaat gtgttaagag tttaattttt ttgttatcat taaaaaagac     5760

aggattataa agagatatca aagcacgatt ttagataacc taaacggccc agcctatacg     5820

aagttgatta tatctcgatg tctgtaaaag attgctgttc ttggagtctt gaggtcttgt     5880

gaattgattt cctgctttct ttcatttttt tcaatttaag taataataca tttgttatat     5940

tcctttcagt gtaagtttct atttggacaa ttttatggga acatgtgcat tctctatgtg     6000

agcttctatc atattcctgt tttattagca gaacctaaag gaatttattt aatgatgttg     6060

tgacattact gctttttctt ttttcttttc ttagttcata tttgcatttt cgttcaagga     6120

tatgcttagc aataaaatgt tcttcccaaa accttgtatg ctgatgcact tttattttct     6180

taacatttga gaaaatctcg cactgaagct aattatgtca tatcttatta aaagccgagt     6240

aagagctaga ccactttcat gtgatagaag atattctaag cagttactaa ttattacatt     6300

atcaaaatgc catatttatg agataattat ctgttacttg aggcattatt ttttagattg     6360

ctatgataga ataaccagga gggagtgcat ttttctggaa agatgataga aacattgtat     6420

tctagaaaag attattggat actatggttt tgtttgtttg tttttgtttt ttgtttttcg     6480

ttttttgttt gttttttttt tgagacagag tctcgctctg tcgcccgggc tggagtgcag     6540

tggcacgatc tcggctcact gcaagctccg cctcccgggt tcacaccatt ctcctgcctc     6600

agccccccga gtaggtggga ctacaggtgc ccgccaccac gcccggctaa ttttttgtat     6660

ttttcgtaga gacggggttt caccgtgtta gccgggatgg tctcgatctc ctgacctcgt     6720

aatccacccg cctcggcctc ccaaagtgct gggattacag gcgtgagcca ccgcgcccgg     6780

cttggatact atgtttttta aaggcatttc gtacctttta cgtattttct ataagtcaac     6840

aagctttaaa cagtatttaa aactatgttc acatagtgcc ataagcacta gaaagtctta     6900

gatgtcttct ttccaagcct cccaccatat taaaatttaa aattaaaaaa cagaatccaa     6960

aaccaaaatt taaatgagtt cttcaatttt aacagcttct tacaagaatt tctgattaca     7020

acttgtttca tacacccatt gtagcagtaa tgtctcatat ttctcgttct ctcagcacac     7080

acttacttgg ccaattggat aatccatcta ccctttgttc ttcactgtaa tctagaaata     7140

tagatttaac tgaacagctg tcctttatcc atatgttggt taccagtttt caaagagtta     7200

gaattttaaa aatatatatt tagttaagcc tgtgccttca agataacatt agtggagtgg     7260

ttatactatc gactatgtta ggaatggggg ggagaaagtc aggttcagtg atgtcaaatt     7320

atgtaaagtt ttttttttgt tcctgtcttc aaagttctgt attagatgtt ctcccatcat     7380

tttttgagat ggagtcttgc agcctacagt gcagtggcat gatattggct cactgcaacc     7440

tctgcctctc aacctcaaac gattctcctg cctcagcctc ctgagtagct gcgactacag     7500

gcatgggcca ccacacccag ctcatttttt aatttatttt ttattttttt agtaaggaag     7560

ggtttcacca tgttggcaag gctggtctcg aactccttac ttcaagtgat ccacccacct     7620

tggccttgca aaatgctggg attataggtg tgagccactc ctcctgaaat ctttctaaat     7680

ctcactaata tataattcta ggactacttt aagcattcac tttttcttta attcaagaaa     7740

catttattga acacttatgt acaagctagt ctactattgg ctattgttac tttgtttcaa     7800

tgaaggcaga aaatggctag aaggatttta agcctttttg tctcttgtat aaatctatac     7860

aggtccagtc tctctttgct catattcaaa ttgaagtttg atctttctcc aaaaaatatc     7920

caagccctgt gtttgtccca gttgaactaa tatcttgatt atatagttta agatcagttt     7980

gataatgtct attgaatatt tactaaatga ttatgggata ttaaattgag agccttggga     8040

gcttatcatc tagtaaagat gaacaaaaaa tggtactata gtgaatgcaa ataagctatc     8100

aaaaagtaca aactaagttg ggagcttaga agaaattatg taagggaagg cttcatagaa     8160

ggggtgacat tttggtaaac cttggaaaac tgataggcag aaataagggc tgtatatcat     8220

tctaagcaaa cccttaaagt gggagcaagc aggatcaaaa ccataatttg gattgatgac     8280

agactgcaaa aagtacattg gaggaagata tgagtaggaa ggtttttgaa atcatgtcaa     8340

tgaatgggaa gagagaaatg ggagaatagc ttgagaagtt caaggtcaag ggctgctttg     8400

tcgagtacaa aggactcgag catatttgaa atgaaaggta ataactgatc tactcttatg     8460

gagcaaccga gtttcctgat agagatgttt atctggggga aaaaggcata agtcaatctt     8520

cttggagaga atgggatcag aaactgacat attgctacag aggttacaaa agctgtagtc     8580

agagggcttc agtgttctgg atatattaaa ggacaaggtc agatacccaa gtgggaccgt     8640

gagtgattaa tggcagcagt ccactgacag caccagtagg aaggcgctaa tgaaaagatc     8700

tctaaatatc agtaaggggt tagctgccat taataataca actttatagc tttactattt     8760

tttcttttat tgttgaaata gtgagggcac gtatttttct aattgtgttt attacaaaga     8820

aaacagaccc gaagaactta aatgacttct ccaaggtcac acagctaata catgacaatg     8880

tcatgactta aaatccagtc ttgtggttcc aaatttagag ctctttcata aacctgtctc     8940

tagagaagca agtcattttc tactttttcc agaagcattt gaagtggaag ctaaggcagg     9000

aaatgagagg atattgtgtt agtctactgg gattaccctg gcaaaatacc acaggctggg     9060

tagacaactg aaatgtattt ctcagttcca gaaacaaagt tgcagatcaa agtttgttag     9120

ggctcagttt ctgggaaggg ctctcttcct ggcttgtaga taataagcta ccttctcact     9180

atgtactcac agggcctttc ttctgttcat gcactgagag atttcttttt cttgctcttc     9240

ttataagacc accagtgcta ttggttaaag ccctgccatt atgactttgt ttgaccttaa     9300

ttacttccta aagacactac ctcccaatac agtcatgttt ggggttggga cttcaacata     9360

tgaatgttgg aggggatatg gttctgtttc tagcaaatgt atagtagtgg gaattgcaaa     9420

ggttgaagtt ccaaagtatc aagggaatca gaattgggaa gcaattctaa cctttttgaa     9480

gtggttacat ggcccaagta gaagagcaaa taattccaag agacaccaag ccacagagca     9540

ggtaggatca cgtgagtagg gcccaggata gaagagcagt gttagggttg catgagagtg     9600

agggcatata agacaacaac agctaaaagc aatgcatgct cagatcttgg gagatgtatt     9660

aaatgagtag agtgaatttc aagatatctg agtttttttt ttttaatgat tacatgggtt     9720

ctagagtcaa aatgccatgg ctcatctggt actgtaactt aagataaact gcttagctaa     9780

ggctcagctt tcatacctat aattttgtta tacttatctt gcaggtttct tgagaaatat     9840

tggatgaaat aattcatgtg aaatgcttaa catatgtgtg acaaataatt atccttaaat     9900

aaatgttggt cgttattaca attggctttg ttacttgatt caggcaggat caaaattagc     9960

tgctatatgc atgactaacc aggaccaaaa agttaataaa aatacgaaag tttggcactc    10020

tt                                                                   10022


<210>  264
<211>  8578
<212>  DNA
<213>  homo sapiens

<400>  264
atatgacttg cccatttgtg aatttggctc cccaactcct cgcttcactt cacctgtgcc       60

tccctggtcc gcgcacttcg caggcgcccg cccgcctctc ggccacctct gcagcctgcc      120

aggcacctcc tcttgcgctc tcgctgattt cgcccaccca cctccctcca ccccgtgcca      180

cgttggtttg ggtggctgct ccgcaccggg ttcctcctcc tctcctcttt ccctccagtc      240

cttcttattc tcttcctctg gctgcggtgg ctgctgctgc tgctggtttt catccagttg      300

ggaaacccag gaagccggcg gctgctccgt ggcgctagtc cagcacgccc agggttaaaa      360

gcctcgcgcc cttccgcgga gactcccagg aacacccgaa gaactcttcc acctgcagcc      420

cccttttgcc tggcagttct gcattgcatc tcatggaagt ggaaacagga aaataaaaat      480

gttcaaactc cttggatgtt gggataaact cacctgaacc cacttgggtt cgggctgcct      540

ccttctcttc cttcattgcc acctttcctc tgtgtggctc ccgggagtgt gcggttaagt      600

catcagactc gaagtgccta gagatccgga ggaagccgcg ccggtcttcc cctgacatgc      660

gtggcatgcc ggggctccgt aggaggtttg ctatacctgg gaggaccctg gcattctaaa      720

tttcagctcc gggaaagaga aggggctttt tgccttttat cttttttttt tctttcttta      780

agtagtaatt ttttaactga ttcattgttt ggaaagcgca tattgcttcc ctcttccccg      840

aattctggca actcttcctc ctgctatgat gggcccttgg gcatcatgaa cttcattact      900

cctcactggc tggaattcaa actgcccatc tgtagtggtc ccgtgcgttg accatgcacc      960

tgagaatcca cgcgagacgg agccctcctc gccggccggc ctggacgctt gggatctggt     1020

tcctgttctg gggatgtatc gtcagctctg tatggagttc ttctaatgta gcttcctcct     1080

cctccacctc ttcctcgccg gggtctcact ctcagcacga gcaccatttc catggcagca     1140

agcatcactc agtgcctatt tctatctatc gttcccctgt ttcccttcga ggaggacacg     1200

ctggcgctac gtacatcttt gggaaaagtg gtgggcttat cctctacacc tggccagcca     1260

atgacaggcc cagcacgcgg tctgaccgcc ttgccgtggg cttcagcacc actgtgaagg     1320

atggcatctt ggtccgcatc gacagtgctc caggacttgg tgacttcctc cagcttcaca     1380

tagaacaggg gaaaattgga gttgtcttca acattggcac agttgacatc tccatcaaag     1440

aggagagaac ccctgtaaat gacggcaaat accatgtggt acgcttcacc aggaacggcg     1500

gcaacgccac cctgcaggtg gacaactggc cagtgaatga acattatcct acaggccggc     1560

agttaaccat cttcaacact caggcgcaaa tagccattgg tggaaaggac aaaggacgcc     1620

tcttccaagg ccaactctct gggctctatt atgatggttt gaaagtactg aacatggcgg     1680

ctgagaacaa ccccaatatt aaaatcaatg gaagtgttcg gctggttgga gaagtcccat     1740

caattttggg aacaacacag acgacctcca tgccaccaga aatgtctact actgtcatgg     1800

aaaccactac tacaatggcg actaccacaa cccgtaagaa tcgctctaca gccagcattc     1860

agccaacatc agatgatctt gtttcatctg ctgaatgttc aagtgatgat gaagactttg     1920

ttgaatgtga gccgagtaca ggtaggtcag caaaccccac ggagccggga atcagacggg     1980

ttccgggggc ctcagaggtg atccgggagt cgagcagcac aacagggatg gtcgtcggca     2040

ttgtggctgc tgccgccctc tgcatcttga tcctcctgta cgccatgtac aagtacagga     2100

acagggacga ggggtcctat caagtggacg agacgcggaa ctacatcagc aactccgccc     2160

agagcaacgg cacgctcatg aaggagaagc agcagagctc gaagagcggc cacaagaaac     2220

agaaaaacaa ggacagggag tattacgtgt aaacatgcga acactgctca cacgcgagtt     2280

ttcacagtta tttctatcca cgcctatgaa tctttggacg gtgagatctc acagatgtca     2340

gaactgctgg aactatgaaa tggggtatat aaccacgact ctggtgggga aaaccgtttt     2400

ttaaaggaca cacacacaca cagcgatgca tctctctcta aagctcagcc acggctgcgg     2460

caaggtccca gcggtcgctg ggagacagaa ggttttgtgc cctgctgtat cataaagcac     2520

acacttagcg ctctggagcc ggacggtggc tccaccactt ccgcaggcct ggaaacttcc     2580

ttctccggag gaccttttac taaaaggtag aagacttcat ggcttacttg ttccataact     2640

ccaagtgagt ctgtaatgtt tgtgaagctt gactgtaacc atgttttttc tgtttaatta     2700

tgtaaaaaac aaaactacaa caacaaaaaa agaaaaaagt taaaaaagaa aaaaacacca     2760

aaaaacaaaa acaaacaaaa aaaaaaaccc acaaccctta tctggttctg accagtgtgc     2820

gtgtaacttt atgatctgag gggaaaaatg gcttttgggt ttttgtttat ttttttgata     2880

atgactggac atcagaagag gaaaaaaact caaaacaaaa gcgagagaga ctattgccat     2940

atgaactcaa aagctatcat ggtgttcact ctacatatca ggttatggtg tctctagaat     3000

ctgttgtttg tttcctataa gatgctttgc tgaacacata gcaaaattca tgtgacggat     3060

gataaattga ttcgaaaagc tggtccccca ggatctaatt tcagaattta ccacccaaac     3120

ccggaacaga tgggtttagg gctggtgtta tcagagctat tggctttacg taacaatatt     3180

gttcctgtcc attcacccag ccaaattgtg ttaaagagga aagccccaca aactaaaaca     3240

gcctttccta gggaagagga aggggaggtg ggctggatct gtgactgatt gaaatgcatg     3300

caaataaaaa agacaatatt aaagtctgtt atcaaaccag acagtagggg agttcaactc     3360

gtgatggaac cacaaaaggt cacacaagcc aaccatgtca tgccagagta caaaacacat     3420

agttctttcc ccgccccgaa tgtgacaatg gttttcatag tggtttaatt ttgtagcctg     3480

acatttatgg ataactctgt ccttccattt gctcacttct ctcttcaccc atctttttta     3540

aaaacaaata aatgaataaa gctgctgtga cacacacaca aaaggaattt aatagtataa     3600

tatatatata aataaatata tatacagata tatttatcat ggtatgtttg atgggatgac     3660

tgacacagga aatctgttaa agtcttaaaa tggaatgaga atgttgtttt aaaagaaaat     3720

agcaaaacaa caaaaaagca aaccttaaaa tgtgaagaaa gtgtgaattt tagttttgtc     3780

acagttaact gtgtcaaaga gaattaaaaa aaaaaacttc agattttgtt tacatatttt     3840

actacatttt tgctggtata attccttagc cacctatgta catactgctt taagaaatgt     3900

ttttttcctg tttatttctg tttggtttat attctggttg tctttttctt tttgtaaaga     3960

ggaaacaatg tacagaaaaa caataaactg gttgtatggc catagctatc cgaaaagcaa     4020

gagacaaagc aagacaaata ttcacacaaa aatgaagtgt gtcctctgga gggtcagata     4080

tacaatttct tttgtacaga tgaaaatcaa tcagctgctt agatttagaa atctactctt     4140

gctggtcttt gtaagttgca tgaatatttg actttgaaaa aatatcttaa cgacatgggg     4200

caaaaagtgc aatctaaatg gtagccttta ctaatgtgtg tggaaagagg tgttcctcat     4260

tatctaatat ttcaatgtgt taagagttta atttttttgt tatcattaaa aaagacagga     4320

ttataaagag atatcaaagc acgattttag ataacctaaa cggcccagcc tatacgaagt     4380

tgattatatc tcgatgtctg taaaagattg ctgttcttgg agtcttgagg tcttgtgaat     4440

tgatttcctg ctttctttca tttttttcaa tttaagtaat aatacatttg ttatattcct     4500

ttcagtgtaa gtttctattt ggacaatttt atgggaacat gtgcattctc tatgtgagct     4560

tctatcatat tcctgtttta ttagcagaac ctaaaggaat ttatttaatg atgttgtgac     4620

attactgctt tttctttttt cttttcttag ttcatatttg cattttcgtt caaggatatg     4680

cttagcaata aaatgttctt cccaaaacct tgtatgctga tgcactttta ttttcttaac     4740

atttgagaaa atctcgcact gaagctaatt atgtcatatc ttattaaaag ccgagtaaga     4800

gctagaccac tttcatgtga tagaagatat tctaagcagt tactaattat tacattatca     4860

aaatgccata tttatgagat aattatctgt tacttgaggc attatttttt agattgctat     4920

gatagaataa ccaggaggga gtgcattttt ctggaaagat gatagaaaca ttgtattcta     4980

gaaaagatta ttggatacta tggttttgtt tgtttgtttt tgttttttgt ttttcgtttt     5040

ttgtttgttt tttttttgag acagagtctc gctctgtcgc ccgggctgga gtgcagtggc     5100

acgatctcgg ctcactgcaa gctccgcctc ccgggttcac accattctcc tgcctcagcc     5160

ccccgagtag gtgggactac aggtgcccgc caccacgccc ggctaatttt ttgtattttt     5220

cgtagagacg gggtttcacc gtgttagccg ggatggtctc gatctcctga cctcgtaatc     5280

cacccgcctc ggcctcccaa agtgctggga ttacaggcgt gagccaccgc gcccggcttg     5340

gatactatgt tttttaaagg catttcgtac cttttacgta ttttctataa gtcaacaagc     5400

tttaaacagt atttaaaact atgttcacat agtgccataa gcactagaaa gtcttagatg     5460

tcttctttcc aagcctccca ccatattaaa atttaaaatt aaaaaacaga atccaaaacc     5520

aaaatttaaa tgagttcttc aattttaaca gcttcttaca agaatttctg attacaactt     5580

gtttcataca cccattgtag cagtaatgtc tcatatttct cgttctctca gcacacactt     5640

acttggccaa ttggataatc catctaccct ttgttcttca ctgtaatcta gaaatataga     5700

tttaactgaa cagctgtcct ttatccatat gttggttacc agttttcaaa gagttagaat     5760

tttaaaaata tatatttagt taagcctgtg ccttcaagat aacattagtg gagtggttat     5820

actatcgact atgttaggaa tgggggggag aaagtcaggt tcagtgatgt caaattatgt     5880

aaagtttttt ttttgttcct gtcttcaaag ttctgtatta gatgttctcc catcattttt     5940

tgagatggag tcttgcagcc tacagtgcag tggcatgata ttggctcact gcaacctctg     6000

cctctcaacc tcaaacgatt ctcctgcctc agcctcctga gtagctgcga ctacaggcat     6060

gggccaccac acccagctca ttttttaatt tattttttat ttttttagta aggaagggtt     6120

tcaccatgtt ggcaaggctg gtctcgaact ccttacttca agtgatccac ccaccttggc     6180

cttgcaaaat gctgggatta taggtgtgag ccactcctcc tgaaatcttt ctaaatctca     6240

ctaatatata attctaggac tactttaagc attcactttt tctttaattc aagaaacatt     6300

tattgaacac ttatgtacaa gctagtctac tattggctat tgttactttg tttcaatgaa     6360

ggcagaaaat ggctagaagg attttaagcc tttttgtctc ttgtataaat ctatacaggt     6420

ccagtctctc tttgctcata ttcaaattga agtttgatct ttctccaaaa aatatccaag     6480

ccctgtgttt gtcccagttg aactaatatc ttgattatat agtttaagat cagtttgata     6540

atgtctattg aatatttact aaatgattat gggatattaa attgagagcc ttgggagctt     6600

atcatctagt aaagatgaac aaaaaatggt actatagtga atgcaaataa gctatcaaaa     6660

agtacaaact aagttgggag cttagaagaa attatgtaag ggaaggcttc atagaagggg     6720

tgacattttg gtaaaccttg gaaaactgat aggcagaaat aagggctgta tatcattcta     6780

agcaaaccct taaagtggga gcaagcagga tcaaaaccat aatttggatt gatgacagac     6840

tgcaaaaagt acattggagg aagatatgag taggaaggtt tttgaaatca tgtcaatgaa     6900

tgggaagaga gaaatgggag aatagcttga gaagttcaag gtcaagggct gctttgtcga     6960

gtacaaagga ctcgagcata tttgaaatga aaggtaataa ctgatctact cttatggagc     7020

aaccgagttt cctgatagag atgtttatct gggggaaaaa ggcataagtc aatcttcttg     7080

gagagaatgg gatcagaaac tgacatattg ctacagaggt tacaaaagct gtagtcagag     7140

ggcttcagtg ttctggatat attaaaggac aaggtcagat acccaagtgg gaccgtgagt     7200

gattaatggc agcagtccac tgacagcacc agtaggaagg cgctaatgaa aagatctcta     7260

aatatcagta aggggttagc tgccattaat aatacaactt tatagcttta ctattttttc     7320

ttttattgtt gaaatagtga gggcacgtat ttttctaatt gtgtttatta caaagaaaac     7380

agacccgaag aacttaaatg acttctccaa ggtcacacag ctaatacatg acaatgtcat     7440

gacttaaaat ccagtcttgt ggttccaaat ttagagctct ttcataaacc tgtctctaga     7500

gaagcaagtc attttctact ttttccagaa gcatttgaag tggaagctaa ggcaggaaat     7560

gagaggatat tgtgttagtc tactgggatt accctggcaa aataccacag gctgggtaga     7620

caactgaaat gtatttctca gttccagaaa caaagttgca gatcaaagtt tgttagggct     7680

cagtttctgg gaagggctct cttcctggct tgtagataat aagctacctt ctcactatgt     7740

actcacaggg cctttcttct gttcatgcac tgagagattt ctttttcttg ctcttcttat     7800

aagaccacca gtgctattgg ttaaagccct gccattatga ctttgtttga ccttaattac     7860

ttcctaaaga cactacctcc caatacagtc atgtttgggg ttgggacttc aacatatgaa     7920

tgttggaggg gatatggttc tgtttctagc aaatgtatag tagtgggaat tgcaaaggtt     7980

gaagttccaa agtatcaagg gaatcagaat tgggaagcaa ttctaacctt tttgaagtgg     8040

ttacatggcc caagtagaag agcaaataat tccaagagac accaagccac agagcaggta     8100

ggatcacgtg agtagggccc aggatagaag agcagtgtta gggttgcatg agagtgaggg     8160

catataagac aacaacagct aaaagcaatg catgctcaga tcttgggaga tgtattaaat     8220

gagtagagtg aatttcaaga tatctgagtt tttttttttt aatgattaca tgggttctag     8280

agtcaaaatg ccatggctca tctggtactg taacttaaga taaactgctt agctaaggct     8340

cagctttcat acctataatt ttgttatact tatcttgcag gtttcttgag aaatattgga     8400

tgaaataatt catgtgaaat gcttaacata tgtgtgacaa ataattatcc ttaaataaat     8460

gttggtcgtt attacaattg gctttgttac ttgattcagg caggatcaaa attagctgct     8520

atatgcatga ctaaccagga ccaaaaagtt aataaaaata cgaaagtttg gcactctt       8578


<210>  265
<211>  1810
<212>  DNA
<213>  homo sapiens

<400>  265
ggcgctgggc ggctgcggcg cgcggtgcgc ggtgcgtagt ctggagctat ggtggtggtg       60

gcagccgcgc cgaacccggc cgacgggacc cctaaagttc tgcttctgtc ggggcagccc      120

gcctccgccg ccggagcccc ggccggccag gccctgccgc tcatggtgcc agcccagaga      180

ggggccagcc cggaggcagc gagcgggggg ctgccccagg cgcgcaagcg acagcgcctc      240

acgcacctga gccccgagga gaaggcgctg aggaggaaac tgaaaaacag agtagcagct      300

cagactgcca gagatcgaaa gaaggctcga atgagtgagc tggaacagca agtggtagat      360

ttagaagaag agaaccaaaa acttttgcta gaaaatcagc ttttacgaga gaaaactcat      420

ggccttgtag ttgagaacca ggagttaaga cagcgcttgg ggatggatgc cctggttgct      480

gaagaggagg cggaagccaa ggggaatgaa gtgaggccag tggccgggtc tgctgagtcc      540

gcagcaggtg caggcccagt tgtcacccct ccagaacatc tccccatgga ttctggcggt      600

attgactctt cagattcaga gtctgatatc ctgttgggca ttctggacaa cttggaccca      660

gtcatgttct tcaaatgccc ttccccagag cctgccagcc tggaggagct cccagaggtc      720

tacccagaag gacccagttc cttaccagcc tccctttctc tgtcagtggg gacgtcatca      780

gccaagctgg aagccattaa tgaactaatt cgttttgacc acatatatac caagccccta      840

gtcttagaga taccctctga gacagagagc caagctaatg tggtagtgaa aatcgaggaa      900

gcacctctca gcccctcaga gaatgatcac cctgaattca ttgtctcagt gaaggaagaa      960

cctgtagaag atgacctcgt tccggagctg ggtatctcaa atctgctttc atccagccac     1020

tgcccaaagc catcttcctg cctactggat gcttacagtg actgtggata cgggggttcc     1080

ctttccccat tcagtgacat gtcctctctg cttggtgtaa accattcttg ggaggacact     1140

tttgccaatg aactctttcc ccagctgatt agtgtctaag gaatgatcca atactgttgc     1200

ccttttcctt gactattaca ctgcctggag gatagcagag aagcctgtct gtacttcatt     1260

caaaaagcca aaatagagag tatacagtcc tagagaattc ctctatttgt tcagatctca     1320

tagatgaccc ccaggtattg tcttttgaca tccagcagtc caaggtattg agacatatta     1380

ctggaagtaa gaaatattac tataattgag aactacagct tttaagattg tacttttatc     1440

ttaaaagggt ggtagttttc cctaaaatac ttattatgta agggtcatta gacaaatgtc     1500

ttgaagtaga catggaattt atgaatggtt ctttatcatt tctcttcccc ctttttggca     1560

tcctggcttg cctccagttt taggtccttt agtttgcttc tgtaagcaac gggaacacct     1620

gctgaggggg ctctttccct catgtatact tcaagtaaga tcaagaatct tttgtgaaat     1680

tatagaaatt tactatgtaa atgcttgatg gaattttttc ctgctagtgt agcttctgaa     1740

aggtgctttc tccatttatt taaaactacc catgcaatta aaaggtacaa tgcaaaaaaa     1800

aaaaaaaaaa                                                            1810


<210>  266
<211>  1820
<212>  DNA
<213>  homo sapiens

<400>  266
ggcgctgggc ggctgcggcg cgcggtgcgc ggtgcgtagt ctggagctat ggtggtggtg       60

gcagccgcgc cgaacccggc cgacgggacc cctaaagttc tgcttctgtc ggggcagccc      120

gcctccgccg ccggagcccc ggccggccag gccctgccgc tcatggtgcc agcccagaga      180

ggggccagcc cggaggcagc gagcgggggg ctgccccagg cgcgcaagcg acagcgcctc      240

acgcacctga gccccgagga gaaggcgctg aggaggaaac tgaaaaacag agtagcagct      300

cagactgcca gagatcgaaa gaaggctcga atgagtgagc tggaacagca agtggtagat      360

ttagaagaag agaaccaaaa acttttgcta gaaaatcagc ttttacgaga gaaaactcat      420

ggccttgtag ttgagaacca ggagttaaga cagcgcttgg ggatggatgc cctggttgct      480

gaagaggagg cggaagccaa ggggaatgaa gtgaggccag tggccgggtc tgctgagtcc      540

gcagcactca gactacgtgc acctctgcag caggtgcagg cccagttgtc acccctccag      600

aacatctccc catggattct ggcggtattg actcttcaga ttcagagtct gatatcctgt      660

tgggcattct ggacaacttg gacccagtca tgttcttcaa atgcccttcc ccagagcctg      720

ccagcctgga ggagctccca gaggtctacc cagaaggacc cagttcctta ccagcctccc      780

tttctctgtc agtggggacg tcatcagcca agctggaagc cattaatgaa ctaattcgtt      840

ttgaccacat atataccaag cccctagtct tagagatacc ctctgagaca gagagccaag      900

ctaatgtggt agtgaaaatc gaggaagcac ctctcagccc ctcagagaat gatcaccctg      960

aattcattgt ctcagtgaag gaagaacctg tagaagatga cctcgttccg gagctgggta     1020

tctcaaatct gctttcatcc agccactgcc caaagccatc ttcctgccta ctggatgctt     1080

acagtgactg tggatacggg ggttcccttt ccccattcag tgacatgtcc tctctgcttg     1140

gtgtaaacca ttcttgggag gacacttttg ccaatgaact ctttccccag ctgattagtg     1200

tctaaggaat gatccaatac tgttgccctt ttccttgact attacactgc ctggaggata     1260

gcagagaagc ctgtctgtac ttcattcaaa aagccaaaat agagagtata cagtcctaga     1320

gaattcctct atttgttcag atctcataga tgacccccag gtattgtctt ttgacatcca     1380

gcagtccaag gtattgagac atattactgg aagtaagaaa tattactata attgagaact     1440

acagctttta agattgtact tttatcttaa aagggtggta gttttcccta aaatacttat     1500

tatgtaaggg tcattagaca aatgtcttga agtagacatg gaatttatga atggttcttt     1560

atcatttctc ttcccccttt ttggcatcct ggcttgcctc cagttttagg tcctttagtt     1620

tgcttctgta agcaacggga acacctgctg agggggctct ttccctcatg tatacttcaa     1680

gtaagatcaa gaatcttttg tgaaattata gaaatttact atgtaaatgc ttgatggaat     1740

tttttcctgc tagtgtagct tctgaaaggt gctttctcca tttatttaaa actacccatg     1800

caattaaaag gtacaatgca                                                 1820


<210>  267
<211>  7102
<212>  DNA
<213>  homo sapiens

<400>  267
ggaaaatggc gaacgactcc cctgcaaaaa gtctggtgga catcgacctc tcctccctgc       60

gggatcctgc tgggattttt gagctggtgg aagtggttgg aaatggcacc tatggacaag      120

tctataaggg tcgacatgtt aaaacgggtc agttggcagc catcaaagtt atggatgtca      180

ctgaggatga agaggaagaa atcaaactgg agataaatat gctaaagaaa tactctcatc      240

acagaaacat tgcaacatat tatggtgctt tcatcaaaaa gagccctcca ggacatgatg      300

accaactctg gcttgttatg gagttctgtg gggctgggtc cattacagac cttgtgaaga      360

acaccaaagg gaacacactc aaagaagact ggatcgctta catctccaga gaaatcctga      420

ggggactggc acatcttcac attcatcatg tgattcaccg ggatatcaag ggccagaatg      480

tgttgctgac tgagaatgca gaggtgaaac ttgttgactt tggtgtgagt gctcagctgg      540

acaggactgt ggggcggaga aatacgttca taggcactcc ctactggatg gctcctgagg      600

tcatcgcctg tgatgagaac ccagatgcca cctatgatta cagaagtgat ctttggtctt      660

gtggcattac agccattgag atggcagaag gtgctccccc tctctgtgac atgcatccaa      720

tgagagcact gtttctcatt cccagaaacc ctcctccccg gctgaagtca aaaaaatggt      780

cgaagaagtt ttttagtttt atagaagggt gcctggtgaa gaattacatg cagcggccct      840

ctacagagca gcttttgaaa catcctttta taagggatca gccaaatgaa aggcaagtta      900

gaatccagct taaggatcat atagatcgta ccaggaagaa gagaggcgag aaagatgaaa      960

ctgagtatga gtacagtggg agtgaggaag aagaggagga agtgcctgaa caggaaggag     1020

agccaagttc cattgtgaac gtgcctggtg agtctactct tcgccgagat ttcctgagac     1080

tgcagcagga gaacaaggaa cgttccgagg ctcttcggag acaacagtta ctacaggagc     1140

aacagctccg ggagcaggaa gaatataaaa ggcaactgct ggcagagaga cagaagcgga     1200

ttgagcagca gaaagaacag aggcgacggc tagaagagca acaaaggaga gagcgggaag     1260

ctagaaggca gcaggaacgt gaacagcgaa ggagagaaca agaagaaaag aggcgtctag     1320

aggagttgga gagaaggcgc aaagaagaag aggagaggag acgggcagaa gaagaaaaga     1380

ggagagttga aagagaacag gagtatatca ggcgacagct agaagaggag cagcggcact     1440

tggaagtcct tcagcagcag ctgctccagg agcaggccat gttactgcat gaccatagga     1500

ggccgcaccc gcagcactcg cagcagccgc caccaccgca gcaggaaagg agcaagccaa     1560

gcttccatgc tcccgagccc aaagcccact acgagcctgc tgaccgagcg cgagaggtgg     1620

aagatagatt taggaaaact aaccacagct cccctgaagc ccagtctaag cagacaggca     1680

gagtattgga gccaccagtg ccttcccgat cagagtcttt ttccaatggc aactccgagt     1740

ctgtgcatcc cgccctgcag agaccagcgg agccacaggt tcctgtgaga acaacatctc     1800

gctcccctgt tctgtcccgt cgagattccc cactgcaggg cagtgggcag cagaatagcc     1860

aggcaggaca gagaaactcc accagcagta ttgagcccag gcttctgtgg gagagagtgg     1920

agaagctggt gcccagacct ggcagtggca gctcctcagg gtccagcaac tcaggatccc     1980

agcccgggtc tcaccctggg tctcagagtg gctccgggga acgcttcaga gtgagatcat     2040

catccaagtc tgaaggctct ccatctcagc gcctggaaaa tgcagtgaaa aaacctgaag     2100

ataaaaagga agttttcaga cccctcaagc ctgctggcga agtggatctg accgcactgg     2160

ccaaagagct tcgagcagtg gaagatgtac ggccacctca caaagtaacg gactactcct     2220

catccagtga ggagtcgggg acgacggatg aggaggacga cgatgtggag caggaagggg     2280

ctgacgagtc cacctcagga ccagaggaca ccagagcagc gtcatctctg aatttgagca     2340

atggtgaaac ggaatctgtg aaaaccatga ttgtccatga tgatgtagaa agtgagccgg     2400

ccatgacccc atccaaggag ggcactctaa tcgtccgcca gactcagtcc gctagtagca     2460

cactccagaa acacaaatct tcctcctcct ttacaccttt tatagacccc agattactac     2520

agatttctcc atctagcgga acaacagtga catctgtggt gggattttcc tgtgatggga     2580

tgagaccaga agccataagg caagatccta cccggaaagg ctcagtggtc aatgtgaatc     2640

ctaccaacac taggccacag agtgacaccc cggagattcg taaatacaag aagaggttta     2700

actctgagat tctgtgtgct gccttatggg gagtgaattt gctagtgggt acagagagtg     2760

gcctgatgct gctggacaga agtggccaag ggaaggtcta tcctcttatc aaccgaagac     2820

gatttcaaca aatggacgta cttgagggct tgaatgtctt ggtgacaata tctggcaaaa     2880

aggataagtt acgtgtctac tatttgtcct ggttaagaaa taaaatactt cacaatgatc     2940

cagaagttga gaagaagcag ggatggacaa ccgtagggga tttggaagga tgtgtacatt     3000

ataaagttgt aaaatatgaa agaatcaaat ttctggtgat tgctttgaag agttctgtgg     3060

aagtctatgc gtgggcacca aagccatatc acaaatttat ggcctttaag tcatttggag     3120

aattggtaca taagccatta ctggtggatc tcactgttga ggaaggccag aggttgaaag     3180

tgatctatgg atcctgtgct ggattccatg ctgttgatgt ggattcagga tcagtctatg     3240

acatttatct accaacacat atccagtgta gcatcaaacc ccatgcaatc atcatcctcc     3300

ccaatacaga tggaatggag cttctggtgt gctatgaaga tgagggggtt tatgtaaaca     3360

catatggaag gatcaccaag gatgtagttc tacagtgggg agagatgcct acatcagtag     3420

catatattcg atccaatcag acaatgggct ggggagagaa ggccatagag atccgatctg     3480

tggaaactgg tcacttggat ggtgtgttca tgcacaaaag ggctcaaaga ctaaaattct     3540

tgtgtgaacg caatgacaag gtgttctttg cctctgttcg gtctggtggc agcagtcagg     3600

tttatttcat gaccttaggc aggacttctc ttctgagctg gtagaagcag tgtgatccag     3660

ggattactgg cctccagagt cttcaagatc ctgagaactt ggaattcctt gtaactggag     3720

ctcggagctg caccgagggc aaccaggaca gctgtgtgtg cagacctcat gtgttgggtt     3780

ctctcccctc cttcctgttc ctcttatata ccagtttatc cccattcttt ttttttttct     3840

tactccaaaa taaatcaagg ctgcaatgca gctggtgctg ttcagattct accatcaggt     3900

gctataagtg tttgggattg agcatcatac tggaaagcaa acacctttcc tccagctcca     3960

gaattccttg tctctgaatg actctgtctt gtgggtgtct gacagtggcg acgatgaaca     4020

tgccgttggt tttattggca gtgggcacaa ggaggtgaga agtggtggta aaaggagcgg     4080

agtgctgaag cagagagcag atttaatata gtaacattaa cagtgtattt aattgacatt     4140

tcttttttgt aatgtgacga tatgtggaca aagaagaaga tgcaggttta agaagttaat     4200

atttataaaa tgtgaaagac acagttacta ggataacttt tttgtgggtg gggcttggga     4260

gatggggtgg ggtgggttaa ggggtcccat tttgtttctt tggatttggg gtgggggtcc     4320

tggccaagaa ctcagtcatt tttctgtgta ccaggttgcc taaatcatgt gcagatggtt     4380

ctaaaaaaaa aaaaaaaaaa aaaaaaaaaa ggaaaaaaaa aaagaaaaag aaaacgtgtg     4440

cattttgtat aatggccaga actttgtcgt gtgacagtat tagcactgcc tcagttaaag     4500

gtttaatttt tgtttaaacc tagacgtgca acaaaagttt taccacagtc tgcacttgca     4560

gaagaaagaa aaaaattcaa accacatgtt tatttttttt ttgcctacct cattgttctt     4620

aatgcattga gaggtgattt agtttatatg tttttggaag aaaccattaa tgtttaattt     4680

aatcttaata ccaaaacgac cagattgaag tttgactttt attgtcacaa atcagcaggc     4740

acaagaactg tccatgaaga tgggaaatag ccttaaggct gatgcagttt acttacaagt     4800

ttagaaacca gaatgctttg tttttaccag attcaccatt agaggttgat ggggcaactg     4860

cagcccatga cacaagatct cattgttctc gatgtagagg ggttggtagc agacaggtgg     4920

ttacattaga atagtcacac aaactgttca gtgttgcagg aaccttttct tgggggtggg     4980

ggagtttccc ttttctaaaa atgcaatgca ctaaaactat tttaagaatg tagttaattc     5040

tgcttattca taaagtgggc atcttctgtg ttttaggtgt aatatcgaag tcctggcttt     5100

tctcgttttc tcacttgctc tcttgttctc tgttttttta aaccaatttt actttatgaa     5160

tatattcatg acatttgtaa taaatgtctt gagaaagaat ttgtttcatg gcttcatggt     5220

catcactcaa gctcccgtaa ggatattacc gtctcaggaa aggatcagga ctccatgtca     5280

cagtcctgcc atcttacttt cctcttgtcg agttctgagt ggaaataact gcattatggc     5340

tgctttaacc tcagtcatca aaagaaactt gctgtttttt aggcttgatc tttttccttt     5400

gtggttaatt ttcctgtata ttgtgaaaat gggggatttt ccctctgctc ccacccacct     5460

aaacacagca gccatttgta cctgtttgct tcccatccca cttggcaccc actctgacct     5520

cttgtcagtt tcctgttcct ggttccatct ttttgaaaaa ggccctcctt tgagctacaa     5580

acatctggta agacaagtac atccactcat gaatgcagac acagcagctg gtggttttgt     5640

gtatacctgt aaagacaagc tgagaagctt actttttggg gaagtaaaag aagatggaaa     5700

tggatgtttc atttgtatga gtttggagca gtgctgaagg ccaaagccgc ctactggttt     5760

gtagttaacc tagagaaggt tgaaaaatta atcctacctt taaagggatt tgaggtaggc     5820

tggattccat cgccacagga ctttagttag aattaaattc ctgcttgtaa tttatatcca     5880

tgtttaggct tttcataaga tgaaacatgc cacagtgaac acactcgtgt acatatcaag     5940

agaagaagga aaggcacagg tggagaacag taaaaggtgg gcagatgtct ttgaagaaat     6000

gctcaatgtc tgatgctaag tgggagaagg cagagaacaa aggatgtggc ataatggtct     6060

taacattatc caaagacttg aagctccatg tctgtaagtc aaatgttaca caaaaaaaaa     6120

tgcaaatggt gtttcattgg aattaccaag tgcttagaac ttgctggctt tcccataggt     6180

ggtaaagggg tctgagctca caccgagttg tgcttggctt gcttgtgcag ctccaggcac     6240

ccggtgggca ctctggtggt gtttgtggtg aactgaattg aatccattgt tgggcttaag     6300

ttactgaaat tggaacaccc tttgtccttc tcggcggggg cttcctggtc tgtgctttac     6360

ttggcttttt tccttcccgt cttagcctca cccccttgtc aaccagattg agttgctata     6420

gcttgatgca gggacccagt gaagtttctc cgttaaagat tgggagtcgt cgaaatgttt     6480

agattctttt aggaaaggaa ttattttccc cccttttaca gggtagtaac ttctccacag     6540

aagtgccaat atggcaaaat tacacaagaa aacagtattg caatgacacc attacataag     6600

gaacattgaa ctgttagagg agtgctcttc caaacaaaac aaaaatgtct ctaggtttag     6660

tcagagcttt cacaagtaat aacctttctg tattaaaatc agagtaaccc tttctgtatt     6720

gagtgcagtg ttttttactc ttttctcatg cacatgttac gttggagaaa atgtttacaa     6780

aaatggtttt gttacactaa tgcgcaccac atatttatgg tttattttaa gtgacttttt     6840

atgggttatt taggttttcg tcttagttgt agcacactta ccctaatttt gccaattatt     6900

aatttgctaa atagtaatac aaatgacaaa ctgcattaaa tttactaatt ataaaagctg     6960

caaagcagac tggtggcaag tacacagccc ttttttttgc agtgctaact tgtctactgt     7020

gtattatgaa aattactgtt gtccccccac ccttttttcc ttaaataaag taaaaatgac     7080

acctaaaaaa aaaaaaaaaa aa                                              7102


<210>  268
<211>  5887
<212>  DNA
<213>  homo sapiens

<400>  268
gaagttgagc aaacacctcc tacttcccgg ccttccatcc cagtttcttc taggaattcg       60

gagcctcccc tgcagcgact cggaagattc gaggcggcgg gggacaagtc ggcgccccag      120

agcggacgag tcaccaggtg tcaagatgct gcaagtacat aggactggac tgggcaggct      180

gggggtcagc ctctccaagg gtcttcacca caaagctgtg ttggccgtcc ggagggagga      240

tgtgaacgcc tgggagagaa gggccccgct agctcccaag cacatcaaag gcatcaccaa      300

tctgggatac aaggtcttga tacagccttc gaatcggcgg gccattcatg ataaggacta      360

tgtcaaagct ggtggcattc ttcaggagga tatttctgaa gcttgtctaa ttttaggagt      420

taaaagacct ccagaggaaa aattaatgtc caggaagact tatgcatttt tctcccacac      480

aataaaagct caggaggcca atatgggctt gttggatgag attctaaaac aggaaattcg      540

ccttattgat tatgagaaaa tggtggatca tagaggagta cgggtagtgg catttggaca      600

gtgggctggt gtggcaggaa tgatcaacat tttacatgga atgggtttaa ggctccttgc      660

tttgggacat cacacacctt ttatgcacat tggcatggct cataactaca ggaatagcag      720

tcaggctgtg caagctgtcc gtgatgctgg ctatgaaata tctttgggtt tgatgcctaa      780

gtcaatagga cccttaacat ttgtgttcac aggaactggt aatgtttcta agggagccca      840

agcaatcttt aatgagctac cttgtgaata tgtggagccc catgaattaa aagaagtttc      900

ccaaactgga gacctcagaa aagtgtatgg gacggtgtta agtcgtcatc atcatcttgt      960

caggaaaaca gatgctgtgt atgatcctgc agagtatgac aaacatccgg agcgctacat     1020

aagtcgtttt aatactgata ttgcacccta tacaacttgc ttaattaatg gaatctactg     1080

ggaacaaaac actcctcgcc tcctaacccg ccaagatgct cagagtctcc tggctccggg     1140

caagttctca cctgctggtg tggaaggctg ccctgcatta ccacacaaac tcgtggcaat     1200

atgtgacatt tcagctgaca caggagggtc tatagagttt atgactgagt gtacaacaat     1260

agagcatccc ttttgcatgt atgatgcaga ccagcatatt attcatgaca gtgttgaagg     1320

ctcggggatc ctgatgtgtt ccattgacaa tttgccggca cagctcccaa ttgaagctac     1380

agaatgcttt ggagacatgc tttaccctta tgttgaagaa atgatattat cagacgcgac     1440

acagcctctt gaaagtcaga atttttctcc tgtggtgaga gatgcagtga ttacatccaa     1500

cggtacatta cctgataaat ataaatatat ccagacactc cgggagagca gggaacgtgc     1560

tcagtcactt tcaatgggca ccaggagaaa ggttttggtt cttggatctg gctacatatc     1620

tgagcctgta ttagaatatt tatcaagaga tggcaatata gaaataacag taggatctga     1680

catgaagaat caaattgaac agttaggcaa gaaatataat attaatcctg ttagcatgga     1740

catttgtaaa caagaagaga agctgggctt cttggtggca aaacaggatc ttgtcatcag     1800

cttgttgcct tatgtattgc accctcttgt ggccaaggcc tgcatcacaa acaaagttaa     1860

catggtcact gcaagctaca tcacaccagc actaaaagaa ttggaaaaga gtgtggaaga     1920

tgctggcatc acaatcattg gtgaattggg attggaccct ggtctggatc acatgttagc     1980

aatggaaaca atagataaag ccaaggaagt gggagccacg attgaatcat atatttccta     2040

ctgtggtggg cttccagccc ctgaacattc aaacaatcca ttgagatata aatttagctg     2100

gagtccagtg ggagttttga tgaatgtaat gcagtctgcc acctatctgc tcgatggaaa     2160

ggttgtgaat gttgcaggag gcatctcctt tcttgatgcc gttacgtcca tggatttttt     2220

tccaggatta aatttggaag gctatcctaa cagagacagt acgaaatatg ctgagattta     2280

tggcatttct tctgctcaca ctttgttgcg ggggacactg agatataagg gatatatgaa     2340

agctttgaat ggatttgtaa aattaggtct tataaacaga gaagcgcttc ctgcctttag     2400

acctgaggcc aaccctctca cctggaaaca actcctctgt gacctagttg ggatttcacc     2460

ctcctctgag catgatgtgt tgaaggaagc tgttcttaag aaactaggag gagacaatac     2520

ccagttggag gctgctgaat ggttgggctt acttggggat gaacaagttc ctcaggcaga     2580

gtccattctg gatgccctct ccaagcattt ggtcatgaag ctttcctatg gtcctgaaga     2640

aaaagatatg attgtgatga gagacagctt tggaatcaga catccttctg gacatttaga     2700

acataaaacg attgatcttg tggcttatgg ggacatcaat ggcttttcag ccatggctaa     2760

aaccgtgggg ttacccaccg ccatggcagc caaaatgttg cttgatggtg aaattggagc     2820

caaaggccta atggggccct tttcaaagga gatctatgga ccaatattgg agcgaattaa     2880

agcagaaggc attatatata ctacacagag tacaattaaa ccataattgg gaattatatt     2940

ttgttttttt cttcccaggc aatacacctc tgaacatgtg tgtgataaat gggtttgcta     3000

atgtgctgtt ttaaagtata aagcataata tgttttggtt aacacaatgt actttttgaa     3060

ctataaatct ttattttaat atggaaatgt ttggaacagg agatgcaagc cactaacaga     3120

gaactttaat aattctaccc tgtattttat aaatacgtat gtgaaagtga tgatcatgct     3180

atttgttaat ttattgtgcc actttttttc ttttgttttt tttttgttgt tgttgttttt     3240

tgagatggag tctcgctctg tcacccaggc tggagtgcag tggcgcgatc tcggctcact     3300

gcaagctccg cctcctgggt tcacgccatt ctcctgcctc agcctcccaa gtagctggga     3360

ctacaggcac ccgccaccac gcccggctaa attttttgta tttttcagta gagacggggt     3420

ttcaccatgt tagccaggat gtccactttt ttcttaaatg aacatattgt cttataacca     3480

gcaaatgaag ttttactttt ttagtcagaa aaaatttcgt cataaagcta tatttttata     3540

tttttaaaat tgatacagtt agataccttc agattaccta agttaagttt ttgccaaaat     3600

gctattttat gccctttttg taaagttatg atttattttg taaatatagt tccttatagt     3660

tttctcttga gtgtttggac atgagaatag ataagattaa attacaattt acaagatcac     3720

ttcattaggc acaggaaaag tatttaacaa aattcaacac cctttcacaa taaaaaataa     3780

aaaataaaaa accctcaaca aactaggaat agaaggaaac ttcctcaacc tgataaaggg     3840

catctatgaa gaacccatgg ttagcatcat acttaatggt gaaggactgg attatttccc     3900

cctgagatca gaaacaagac aaggatgtct gctttggcca tttctattca acttgtactg     3960

gacagtcaag aaagggcaat taggcaagaa aataaaataa aagtcatcta ggttggaaag     4020

gaagaagtat aactaaatag agatgggaga cgatatggtg gttttgtgca tagtaatcca     4080

agggaaaact atagaaaatc caaaggcatg atttattaat aaataaattc agcaaagtta     4140

caggatacag gattaaatat gcagaaattg gttatctttc aatatagtat caatgaataa     4200

atcaaaaatg atgttaagaa aacaatttaa ttttcaacaa tggtcaagct tggtggcttg     4260

tgcctgtaat cccaacactt tgggagtctg aggcagaaag actgctagag gccaggagac     4320

cagcctggga aacagtgaga tcccatctct acaaaaacaa acaaacaaaa aacaacaagc     4380

aaacaaaaaa cagctggatg tgatgacact catctgtcgt ctcagctact cagaggctga     4440

ggtgtaagga tggcttgagc cccaaagttc gaagctgcaa tgagctataa ctgggtcact     4500

gcaatccagc ctggatgaca gagttagacc ttgactcaaa aaaaacaaaa aagaaaagaa     4560

aaaaattgac agcatcagaa agagtaaaat accaatataa ttgagggtcc agaaatattg     4620

atcacattta tcatcaactg acttttgaaa atagtgctaa gacaattcaa tgggggcaaa     4680

atagtctttt tcattaaatg atgcttggaa acatggatat ccacatgcaa aataatgaaa     4740

ttggactcct acctcatatt gcatataaaa attaactcaa agttgaccta agatctaaat     4800

gtaagagcta atattgtaag tatcttcaaa gaaaacatgg cgtaaatctt tctgactttg     4860

aattaggcaa tgatttctta aataaatgac actaaaaaca caagcaacaa aagaagaaaa     4920

taggtaaatt aaaattaaaa ccatttgtgt ttccaaggac aatatcaaga aagcaaaaat     4980

acaacccaca gaatgagata atttttttta aaatcatgta ttagttaagg gaggaatttg     5040

tatttagaat atgtaaagaa ctgttacaat aataattaaa aggcatataa ttcaattttt     5100

aaaaatcaac aagagatctg aattaacagt tctccaaaga agatacacaa aaggccaata     5160

agcacatgaa aaggttctca acatcactag ccatcaggga aatgcaaatg agatctacaa     5220

tgagatatca cttaacactc actggaatag atatataatc aaagtgataa tatcaagtgt     5280

tggtgaggat gcagagaaat tggaaccctc atgcactgtt ggtggatacc cacgtgatat     5340

aaaaacaaat gtctacacaa aaacttgtgc acagatgttc tttgcagcat tatttataat     5400

agcccaaaat tgaaacagcc ctaatttcta tcaactaaca agtgaataaa caaaacgtgg     5460

catatccata caaggaatat tattcagcaa taaaaaaaga gatgaagtac tgatatgcac     5520

cacaacatgg aaaaaccttg aaaacatatc aagtgaagaa tgccagacat gaaaggccac     5580

atattatatg atttcattta tatgaaatgt ccagaacagg cgaatatata tagagagaag     5640

gcagattagt ggttgcttag gctgaagggt tggggaggac aaaggggtga ctgctaatta     5700

gtatggggtt tcttttttgg ggtgatgtaa acgttgtaaa gttgattgtg gtaatggtgg     5760

cacaactctg aatatactaa aaaccactga attgtatact ttgaatgttt gaactgtgtg     5820

gtatgtagat tttatctcaa gttgttataa aaaattaaat tacaaatgca aaaaaaaaaa     5880

aaaaaaa                                                               5887


<210>  269
<211>  3152
<212>  DNA
<213>  homo sapiens

<400>  269
acttcatggc ttctcacgct tgtgctgcat atcccacacc aattagaccc aaggatcagt       60

tggaagtttc caggacatct tcattttatt tccaccctca atccacattt ccagatgtct      120

ctgcagcaaa gcgaaattcc aggagaagag gacaaagata ctcagagaga aaaagtaaaa      180

gaccgaagaa ggaggctgga gagaccagga tccttccagc tgaacaaagt cagccacaaa      240

gcagactagc cagccggcta caattggagt cagagtccca aagacatggg cttgttagag      300

tgctgtgcaa gatgtctggt aggggccccc tttgcttccc tggtggccac tggattgtgt      360

ttctttgggg tggcactgtt ctgtggctgt ggacatgaag ccctcactgg cacagaaaag      420

ctaattgaga cctatttctc caaaaactac caagactatg agtatctcat caatgtgatc      480

catgccttcc agtatgtcat ctatggaact gcctctttct tcttccttta tggggccctc      540

ctgctggctg agggcttcta caccaccggc gcagtcaggc agatctttgg cgactacaag      600

accaccatct gcggcaaggg cctgagcgca acggtaacag ggggccagaa ggggaggggt      660

tccagaggcc aacatcaagc tcattctttg gagcgggtgt gtcattgttt gggaaaatgg      720

ctaggacatc ccgacaagtt tgtgggcatc acctatgccc tgaccgttgt gtggctcctg      780

gtgtttgcct gctctgctgt gcctgtgtac atttacttca acacctggac cacctgccag      840

tctattgcct tccccagcaa gacctctgcc agtataggca gtctctgtgc tgatgccaga      900

atgtatggtg ttctcccatg gaatgctttc cctggcaagg tttgtggctc caaccttctg      960

tccatctgca aaacagctga gttccaaatg accttccacc tgtttattgc tgcatttgtg     1020

ggggctgcag ctacactggt ttccctgctc accttcatga ttgctgccac ttacaacttt     1080

gccgtcctta aactcatggg ccgaggcacc aagttctgat cccccgtaga aatccccctt     1140

tctctaatag cgaggctcta accacacagc ctacaatgct gcgtctccca tcttaactct     1200

ttgcctttgc caccaactgg ccctcttctt acttgatgag tgtaacaaga aaggagagtc     1260

ttgcagtgat taaggtctct ctttggactc tcccctctta tgtacctctt ttagtcattt     1320

tgcttcatag ctggttcctg ctagaaatgg gaaatgccta agaagatgac ttcccaactg     1380

caagtcacaa aggaatggag gctctaattg aattttcaag catctcctga ggatcagaaa     1440

gtaatttctt ctcaaagggt acttccactg atggaaacaa agtggaagga aagatgctca     1500

ggtacagaga aggaatgtct ttggtcctct tgccatctat aggggccaaa tatattctct     1560

ttggtgtaca aaatggaatt cattctggtc tctctattac cactgaagat agaagaaaaa     1620

agaatgtcag aaaaacaata agagcgtttg cccaaatctg cctattgcag ctgggagaag     1680

ggggtcaaag caaggatctt tcacccacag aaagagagca ctgaccccga tggcgatgga     1740

ctactgaagc cctaactcag ccaaccttac ttacagcata agggagcgta gaatctgtgt     1800

agacgaaggg ggcatctggc cttacacctc gttagggaag agaaacaggg tgttgtcagc     1860

atcttctcac tcccttctcc ttgataacag ctaccatgac aaccctgtgg tttccaagga     1920

gctgagaata gaaggaaact agcttacatg agaacagact ggcctgagga gcagcagttg     1980

ctggtggcta atggtgtaac ctgagatggc cctctggtag acacaggata gataactctt     2040

tggatagcat gtcttttttt ctgttaatta gttgtgtact ctggcctctg tcatatcttc     2100

acaatggtgc tcatttcatg gggtattatc cattcagtca tcgtaggtga tttgaaggtc     2160

ttgatttgtt ttagaatgat gcacatttca tgtattccag tttgtttatt acttatttgg     2220

ggttgcatca gaaatgtctg gagaataatt ctttgattat gactgttttt taaactagga     2280

aaattggaca ttaagcatca caaatgatat taaaaattgg ctagttgaat ctattgggat     2340

tttctacaag tattctgcct ttgcagaaac agatttggtg aatttgaatc tcaatttgag     2400

taatctgatc gttctttcta gctaatggaa aatgatttta cttagcaatg ttatcttggt     2460

gtgttaagag ttaggtttaa cataaaggtt attttctcct gatatagatc acataacaga     2520

atgcaccagt catcagctat tcagttggta agcttccagg aaaaaggaca ggcagaaaga     2580

gtttgagacc tgaatagctc ccagatttca gtcttttcct gtttttgtta actttgggtt     2640

aaaaaaaaaa aaagtctgat tggttttaat tgaaggaaag atttgtacta cagttctttt     2700

gttgtaaaga gttgtgttgt tcttttcccc caaagtggtt tcagcaatat ttaaggagat     2760

gtaagagctt tacaaaaaga cacttgatac ttgttttcaa accagtatac aagataagct     2820

tccaggctgc atagaaggag gagagggaaa atgttttgta agaaaccaat caagataaag     2880

gacagtgaag taatccgtac cttgtgtttt gttttgattt aataacataa caaataacca     2940

acccttccct gaaaacctca catgcataca tacacatata tacacacaca aagagagtta     3000

atcaactgaa agtgtttcct tcatttctga tatagaattg caattttaac acacataaag     3060

gataaacttt tagaaactta tcttacaaag tgtattttat aaaattaaag aaaataaaat     3120

taagaatgtt ctcaatcaaa aaaaaaaaaa aa                                   3152


<210>  270
<211>  4335
<212>  DNA
<213>  homo sapiens

<400>  270
acgtaccagg gctcattgcg tgacggttac acttccggcg ggctacgtgc gcgcggcgag       60

cgccgggcgt acttttgcgt ggttgctcca ccccctcagc cttgccttcg ccgccgttgg      120

ggctggaagt tcccgccagg tccgtgccgg gcgagagaga tgctgcccgg cccgcctcgg      180

ctttgaggcg agagaagtgt cccagaccca tttcgccttg ctgacggcgt cgagccctgg      240

ccagacatgt ccacagggtt ctccttcggg tccgggactc tgggctccac caccgtggcc      300

gccggcggga ccagcacagg cggcgttttc tccttcggaa cgggagcgtc tagcaaccct      360

tctgtggggc tcaattttgg aaatcttgga agtacttcaa ctccagcaac tacatctgct      420

ccttcaagtg gttttggaac cgggctcttt ggatctaaac ctgccactgg gttcactcta      480

ggaggaacaa atacaggaat agcaacaact ataactacag gattaactct gggaacgcca      540

gccactacat ctgcagctac aacaggcttc agtttaggat tcaataaacc tgcagcatct      600

gccacaccat ttgctctacc tattacctct acctcagcta gcggtctgac tctttcgtct      660

gctctgacat caactccagc agcatccaca ggatttactc taaataattt gggtgggaca      720

acagccacaa ctacaactgc atcaacaggc ctctctttag ggggagcctt agctggtttg      780

ggaggttcac ttttccagag tacaaacaca ggaacatcag gacttggaca gaatgcttta      840

gggttgactt tgggaactac agcagctact tcaactgcag gcaatgaagg ccttggtggt      900

atagatttca gtagctcctc agataaaaag agtgataaaa cgggaacaag accagaggat      960

agtaaagctc tgaaggatga aaatctacct cctgtcatct gccaggatgt tgaaaatctc     1020

cagaaatttg tgaaggagca gaaacaagtt caagaagaaa ttagtagaat gtcttcaaaa     1080

gcaatgctta aggtacaaga agatattaaa gctctgaagc agctcctgtc gttggctgcc     1140

aatggaatac agagaaacac tctcaacatt gacaaattga aaatagaaac tgctcaggag     1200

ttgaagaatg ctgaaatagc tttaagaacc cagaagacac cacctggact tcaacatgaa     1260

tatgcagctc ctgctgacta cttcagaatc ttggttcagc aatttgaggt acagcttcag     1320

cagtacaggc agcagattga agaactagaa aaccatcttg ccactcaagc aaataattca     1380

catataaccc ctcaagattt gtcaatggct atgcagaaaa tttatcaaac atttgtagct     1440

ttagcggcac aacttcagtc tattcatgaa aatgtaaagg ttctgaaaga acagtacctt     1500

ggctacagga aaatgttctt gggagatgct gttgatgtgt ttgaaacaag gcgagcagaa     1560

gccaagaagt ggcagaacac acccagagtt actactggac ccactccttt cagcaccatg     1620

ccaaacgcag cagccgttgc catggctgca acacttacac agcagcaaca gcctgctaca     1680

gggccacagc catctctggg agttagtttt ggaacgccat tcggctcagg tattggcact     1740

ggcttgcaat caagtggctt aggttcttca aaccttggag gatttggaac tagctctggt     1800

tttggatgca gcaccacagg ggcctccaca tttggatttg gaacaacaaa taaaccctca     1860

ggaagtctta gtgcaggctt tggcagctca agtacatctg ggtttaactt cagcaatcct     1920

ggcatcacgg catcagctgg tttgactttt ggggtgtcca atcctgcctc tgcaggtttt     1980

ggaacaggag gacaactcct tcagttgaag aaacctccag ctggaaacaa aagaggaaaa     2040

agataaacat gggttgatgt gttgagagaa tccatagcag caccgttcat tctatgagtc     2100

tatttttcta atgatgcagt aattaaattg catcccagga gatttataaa gttttgatat     2160

ttttccctac tctggaattt gaactttctt catgtttgcc atactgaaca tcttttttct     2220

tgtggaattt aaagtccagc tgtgttttct ttttaatttg attctcagtg taagaaatgt     2280

tctgattaca tcactgattg gtaatggtta gaaaccatta acctaaaact tactatttaa     2340

cctagtgttt ttgttgatga ggtttacatt atgtgaatac atgcacattt gtttcttata     2400

caggtggtgt gaactctagg gcctatacta gaatcaattt gttccttgtt aaaggccttt     2460

tgaattatac tgcagggcat cttgtgaata tgtatgtaaa tatatacaga ataatacaca     2520

cagttgtgtg tgcatataaa atacatattt acgccaggcg tggtggctca cgcctgtaat     2580

cccagcactt tgggaggccg aggcaggcgg atcacctgag gtcaggagtt tgagaccagc     2640

ctgacatggt gaaaccccat ctctacgaaa aatacaaaaa ttagctgggc atagtggcgg     2700

gtacctataa tcccagctac tcgggaggct gaggcacgag aatcacttga agccgggagg     2760

tgggggttgc agtgagccga gatcacacca ctgcactcca gcctgggcaa caagagcaaa     2820

actccgtctc aaaaaagatg aaaataaaat aaaatatata tttacaggcc tacaactttt     2880

gcctcagact gttccccttt tctaagggta ttcaagtttt caccttttaa gcttcatatc     2940

ctcagtgctt gtagaatgat gagcttagag gtaccaggtc attgcagttg tttgcttaaa     3000

gacttattga aatggttact ggcgtaaata cttggccaac tcaactttat tgcccctgat     3060

cttttccatt tttgtttcca ccttaaccta tagcagctcc tccaaatgag gaatgctgta     3120

agtaagactc atcaaacaga ttttaaccat tttattatcc tgtgtgtcct tacattgctt     3180

ctgtgagatg tttttttctt atctgagatg aactttcagg agcctatttg aactccagac     3240

tggtgttctg gggcaaagag ctattagcca aactgattct atgcaggtga aggatgcact     3300

aaagttctca ctttagtgag aacttttcta gctattccaa tacagagttc tttcttatag     3360

ggctattgat attgacacca aatggagtgg cttctcagcc tcttaatgtc ttaagtaagt     3420

gcttaatttg gaatagagaa accagtatat tttaaaaaag aaaaatattc tttgtagcaa     3480

ctgtaaattc tcccattata acagtgaaca gagctccagg taataacgca taggcatgtc     3540

aggttgcatc tgtatatttg actacattag tattagtgac atcaggtgga tataaaagaa     3600

aacccttgga aagagaactg ccttagccat gatttcgtta gtagacctat ttatgattca     3660

attgcaattt tcagatagga tgtgaacatg gaatttcatt gaaaatagtt taatttttta     3720

tataaaaggt tttgtatata atgtgtgtca gtgactattt tcaaaatcat tttcatcaag     3780

acaccttttt tctaaaatag gcattgcata cacatatgca cacgtatgtg catgtgccac     3840

acattttttg tataatgttg ggtttgatta taaaagtgtt gtcaaatgtt ttatttatct     3900

gcatatagca gtggttggct tttttgaatt gaaatttttg cgcattgatg cattgaaata     3960

aggaaaatta tttatctctg agcactaaac ttatttttgc atatttctgt aatattgcag     4020

tccccagatc cagaacatgg gaagttaggg aaaatgtgtg attttgtgtt ttgaattact     4080

gtcagaatta catacacaat tacaacaaac tttttttaaa agacatttca ttgtactgca     4140

aaaatctgaa tatttatatt tcttgttttt ttctttatat gttttgcatt ttaatatgtt     4200

gagccactgg aaatttgtaa cagattaatt tgttatagga gtttaaatgt gttgtcattg     4260

tctccattgt ctttgtccag agcctattat tatggaaaca ataaaattta ttgtgtcagt     4320

tgctttgatt cttta                                                      4335


<210>  271
<211>  1509
<212>  DNA
<213>  homo sapiens

<400>  271
ccgttgcgcc tgcgcgcggt gcggccgtcg cccctctttt cgcggcgttc tccacctgcg       60

cgggcctgaa tggccttcag gagcacagtc ggcctgagga gttgacggtt actcaccgcc      120

gtgagcccaa gtaactcgcc ctccttcggc tagaaaccct ccgcctgggc ccgcgcgaca      180

ggagcgcggt ctctgagggg agcggcgacc ccgccagccc cggtctcttt ccctggcggc      240

ggcggcttct tccgtgggac aatatgttca agagaatggc cgaatttggg cctgactccg      300

gcgggagagt aaagggtgtt actatcgtta aaccaatagt ttacggtaat gttgctcggt      360

attttggaaa gaaaagagaa gaagatgggc acactcatca gtggacagta tatgtgaaac      420

catatagaaa tgaggatatg tcagcatatg tgaagaaaat ccagtttaaa ttacatgaaa      480

gctatggcaa tcctttaaga gttgttacta aacctccata tgaaattact gaaacaggat      540

ggggtgaatt cgaaataatc atcaaaatat ttttcattga ccctaatgaa agacctgtaa      600

ccctgtatca tttgctaaag ctgtttcaat cagacaccaa tgcaatgctg gggaaaaaga      660

cagtggtttc agagttctat gatgaaatga tatttcaaga cccaacagca atgatgcaac      720

aattattgac aacatctcgt cagctaacat taggagccta taagcatgaa acagaatttg      780

cagagcttga agtgaaaacc agagaaaaat tagaagctgc taagaaaaaa acaagctttg      840

agattgcaga gcttaaggag agattaaaag caagtcgtga aactataaat tgtttaaaaa      900

atgaaatcag aaaacttgaa gaagatgacc aagcaaaaga catataaaca gttctcatga      960

gaacttggta gtaagctaaa ctgaaaataa ggtgggcttc actggagaaa tggacttact     1020

gcaaatgctg tgatgtttct tagaggaact tcatatacag ctgttgacca tgaatttctt     1080

agcaatagga atttgtacta tttaagcaat ctttaatgga aaatatgtgt gtaagaatgg     1140

atgctatata ggtattttac caacccattt taagaaaatt ctatgatatt aagcacagtt     1200

tttaaaaatg tttattgtag tatatgtata gcttattacc cttttgacag gcatcaaaat     1260

ttcattataa agtattactt gtacaaattt tgtacttctt tagtggctag aattagtgaa     1320

gaaacttaat gtgtatattt aatttcttca agttcttacc tgcccccatc cttttttgta     1380

tatgatgtgt ccagtaagta ttcaataaat gtagtttaca gatcctattt ctccctcctg     1440

atgtgtttct tcctctttga agactttctg gaactccctc aatacagtta aagtatcttt     1500

aaaaaaaaa                                                             1509


<210>  272
<211>  4234
<212>  DNA
<213>  homo sapiens

<400>  272
aagaatcgtt tggtctcctg ccgtgcccgg ttcgtattcc ctactccctg ccacgagccg       60

ccccgtccgg gatcctccac ccgtccaaag ttgtgagggg gcgccgggcg tgctcgcgga      120

tcggcggccg cgggcgtgcg gagggctgga cgagccctgg agcgccagga atcccagtca      180

gaagttccag cctgccactg ttctctgatg ccatgccagc accaactcaa ctgttttttc      240

ctctcatccg taactgtgaa ctgagcagga tctatggcac tgcatgttac tgccaccaca      300

aacatctctg ttgttcctca tcgtacattc ctcagagtcg actgagatac acacctcatc      360

cagcatatgc taccttttgc aggccaaagg agaactggtg gcagtacacc caaggaagga      420

gatatgcttc cacaccacag aaattttacc tcacacctcc acaagtcaat agcatcctta      480

aagctaatga atacagtttc aaagtgccag aatttgacgg caaaaatgtc agttctatcc      540

ttggatttga cagcaatcag ctgcctgcaa atgcacccat tgaggaccgg agaagtgcag      600

caacctgctt gcagaccaga gggatgcttt tgggggtttt tgatggccat gcaggttgtg      660

cttgttccca ggcagtcagt gaaagactct tttattatat tgctgtctct ttgttacccc      720

atgagacttt gctagagatt gaaaatgcag tggagagcgg ccgggcactg ctacccattc      780

tccagtggca caagcacccc aatgattact ttagtaagga ggcatccaaa ttgtacttta      840

acagcttgag gacttactgg caagagctta tagacctcaa cactggtgag tcgactgata      900

ttgatgttaa ggaggctcta attaatgcct tcaagaggct tgataatgac atctccttgg      960

aggcgcaagt tggtgatcct aattcttttc tcaactacct ggtgcttcga gtggcatttt     1020

ctggagccac tgcttgtgtg gcccatgtgg atggtgttga ccttcatgtg gccaatactg     1080

gcgatagcag agccatgctg ggtgtgcagg aagaggacgg ctcatggtca gcagtcacgc     1140

tgtctaatga ccacaatgct caaaatgaaa gagaactaga acggctgaaa ttggaacatc     1200

caaagagtga ggccaagagt gtcgtgaaac aggatcggct gcttggcttg ctgatgccat     1260

ttagggcatt tggagatgta aagttcaaat ggagcattga ccttcaaaag agagtgatag     1320

aatctggccc agaccagttg aatgacaatg aatataccaa gtttattcct cctaattatc     1380

acacacctcc ttatctcact gctgagccag aggtaactta ccaccgatta aggccacagg     1440

ataagtttct ggtgttggct actgatgggt tgtgggagac tatgcatagg caggatgtgg     1500

ttaggattgt gggtgagtac ctaactggca tgcatcacca acagccaata gctgttggtg     1560

gctacaaggt gactctggga cagatgcatg gccttttaac agaaaggaga accaaaatgt     1620

cctcggtatt tgaggatcag aacgcagcaa cccatctcat tcgccacgct gtgggcaaca     1680

acgagtttgg gactgttgat catgagcgcc tctctaaaat gcttagtctt cctgaagagc     1740

ttgctcgaat gtacagagat gacattacaa tcattgtagt tcagttcaat tctcatgttg     1800

taggggcgta tcaaaaccaa gaatagtgag tggctctttc actggcaatt ctcaaatgat     1860

atacatttaa agggcagatt ttttaaaaag atactactat aataaacatt tccagttggt     1920

cattctaagc atttaccctt ttgatactct agctagtcag gtactccaaa ttgactttgc     1980

agcagggtgg cagggtcagg agagtctggt cctgcctagc tcagatttca tggcacctgc     2040

acttgaagca agtcacttct ttatcacagg tgtcttgaaa cattagcttc ttttaccaac     2100

ctgagaaaat taggatgacc tggcaaataa gatcttgaat aggccaaaag caagtatctt     2160

gctgtgtgta gtctcttggt taaagtgaag aaacagtact gttcacacct ttcttcactg     2220

agattccagt gtacatgaga acatatattt attgcatgat tttctagata cacagtctat     2280

gcattattca tatacattta ttttagccta aagtggtttt caaatccagt tcttcaagcc     2340

ataaatgacc aagatccaag caatctgaat ttgtttttgt gattatttga ctggaatgct     2400

tcttaagtgg aataactata ctccgttatc cacccgattt cctaatgtaa ttgaaagatt     2460

ttctattttg ccacacactt ggagacaata agggttttta gttttatcta ctcttctatt     2520

gaagttaaag aaagaaaaaa agattttttt atttgtatta atgaaaagct ttagtttaaa     2580

ataaggagat ccagaataaa aagaagagac tgatctcttc aattattgtc atctgtagcc     2640

accagcacat cactcttatg taatccccaa aggcttggca tgccgtaagt gtgtggtggg     2700

tagactgctg ccggggaatc gtacttctta tttagtaatg ataagacttt tcattatttt     2760

tggaatttta aagatgacat aaataagttt aaatatcaat ttggggagta aggtttaata     2820

ttgccatcgg gtattgagac aggaggaagt ttctgttttt ctccatttag acataggtca     2880

attaaaatat ttgggtttaa aatgactaaa tgctttaaac atattgtagc ttaagatata     2940

tgtgttaaga tatatacatg agaaacttta aaaggtaact actgtgcatg cctgatgctt     3000

aatagaatac ttagtggcat caaatgtttg cagcagtctc cataattata ttcagtccct     3060

tctaatactg tatcaatgta aatgaaataa atatattcaa attggctttt tgatatgcat     3120

caagtggcat tttgttcctg tgtttaatag tgatctgtat acagctgtgc acatattgtc     3180

atcacttatt ctagcatcac tgttaaggct gtgattatgt ttgatattca cctggatttt     3240

aatacaagcc aatatcagct tcccattgtg taataacttg ggtgtttagg agtcttttca     3300

cattttttgg ggatatgaac tagatgttca agaactcctt ctggactgtg gatactgaat     3360

cagtgtacta ttggctgcag aatttgtttc aattgaaaat agactcagga agattgctgc     3420

tcagaatatc atataatgtt tattttttga ggtgtttttg tttttatttg tgtgtttttt     3480

tttttttaag tcagcttgga acttttttcc tgggtagtat ttgggagagg gaaaggctgt     3540

actatatatt tatttctaaa tgttttgact gggcattttt cttttaatga aatatgtgga     3600

ctgctctagc aaaccctatt ttcagctact atttgaatat tcttgaacac caccactgaa     3660

gagtttcata tacaccaaat aatgtctcat ctctatagta cagggaatat aaaattggtt     3720

tcctgtggtc atgatcaaga tagtagtatt attacacaag aaacttggtc tgcagtctgg     3780

aagcttgtct gctctataga aatgaaaatg cagcatgaag ttgacattgt ggaaatgaaa     3840

gtaattgggt attagaaatc tgaaagtact gtcatctaaa agcaattgtg attttattgt     3900

aattggttgt cactgttgta cggtgtctag aattaaagaa tacatgtaaa ctttcatggt     3960

atttagcctt tcttaaattt ttttaaaatt taaactttct aacctatgta ttcaacttct     4020

gtatttatat ttaatcagtg gttcatgtta tataatacac ccttaactag ttaaatggaa     4080

tgttggtatg gtacagagta ccatattgct aagaaaactg tcttataaaa gatgtatatg     4140

tgtgaagaca tgaaagttta atgtacagaa tggttggaga aatgcctatg gtgaattaaa     4200

gcttcatatc tgctttctga aaaaaaaaaa aaaa                                 4234


<210>  273
<211>  2125
<212>  DNA
<213>  homo sapiens

<400>  273
cgacgacaag gatggggccc atctcttcgg agcctaagga tccagcccag gtccagccct       60

gcgcagccgc ccaccaagct gccagaagac gagccggacg cccaaggcta cgagaggacg      120

attgcagaat tgtacaggct agtggttggg gaatattttt tcgtggaagg gaccgtcttc      180

cttagctgtg gccctctcat caggtctggg aagaggtaat tggaaaatag aactcatgga      240

gaagtgttac cacaggccat ggacaaggcc agaatttccc tgacatctgt ccgccagcac      300

cgcccttcag gtacaattcc acaagagacc ccccaaactt gatgaagtca cccgcttaca      360

agggctcact ctccacctgc gcaaggactg caattcccag gggcctccag ggcacccggc      420

cgctccagtc cagtcgtgca ggcggcgcgc tctttctcgc tccgctcaag tccaggaacc      480

ggttcccggg ctcccagcct ctcggcagcg cccacgcgcc tgggccaaag tccgcgaacg      540

gaagccggcg gcgaggagga ttctgggagt tggaggccga ggctgcgacc tgcgcaggcg      600

caaacctgcc cctggggtga gggctgtaag tggcgcgatt cgcggcagcg ccccgatgga      660

acctcctggt cctgtgaggg ggcccttgca agattccagc tggtatgagc cttctgcaga      720

gctagtgcag actaggatgg ctgtatcact aacagcagct gaaactctgg cccttcaggg      780

tacacaggga caagagaaga tgatgatgat gggaccaaag gaagaggaac agtcttgtga      840

gtatgagacc aggctacctg ggaaccactc taccagtcaa gagatcttcc gccaacgctt      900

caggcatctc cgctaccagg agactcctgg tccccgggag gccttgagcc aactacgagt      960

actctgctgt gagtggctga ggccagagaa acacacgaag gagcagatcc tggagttcct     1020

ggtgctggaa caattcttga ccatcctgcc tgaggagctc caatcctggg tgcggggaca     1080

tcaccctaag agtggagagg aggctgtgac tgtgctggag gatttagaga aaggacttga     1140

accagagccg caggtcccag gccctgcaca tggacctgca caggaagagc catgggagaa     1200

gaaggaatct ctgggagcag cccaggaagc actgagcatc cagctccagc ctaaggagac     1260

ccagcctttc ccaaagagtg aacaggtata tttacatttt ctgtcagttg ttacagaaga     1320

tggcccagag cccaaggaca aaggatcatt gccacaacca cccattactg aagtggaatc     1380

acaggtgttc tcagaaaaac ttgctactga cacctctaca tttgaagcta cctctgaggg     1440

taccttagaa ctgcagcaga gaaatcccaa agcggagaga ctgaggtggt cccctgccca     1500

ggaggaaagt ttcaggcaga tggttgtcat ccataaggaa attcccacag ggaagaaaga     1560

ccatgaatgt agtgaatgtg gtaaaacctt catttataac tcacatcttg ttgtccacca     1620

gagagttcat tctggagaga aaccctataa gtgtagtgac tgtgggaaaa ctttcaaaca     1680

gagctcaaac ctcggtcagc atcagagaat tcatacagga gagaaaccct tcgaatgtaa     1740

tgaatgtggg aaggccttca gatggggtgc tcatcttgtt cagcatcaga ggattcactc     1800

aggagagaag ccctatgagt gtaatgagtg tgggaaggcc tttagtcaaa gctcatatct     1860

aagtcagcat cggagaattc acagtggaga gaaacctttt atatgtaaag aatgtgggaa     1920

agcttatgga tggtgctcag agctcattag acatcggaga gttcatgcca gaaaagagcc     1980

ttcccattga attgaagggg agaacgtctc cagacagaat tctacatcgg tctaatctac     2040

tttaggactg gatcccataa aagttataag ttccttaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaa                                           2125


<210>  274
<211>  2141
<212>  DNA
<213>  homo sapiens

<400>  274
gccgacgcgt gcagacgtcc ttctaatcct agtcttcgtt tggtccggtt gcactcttcc       60

tatagcccag agggcgagag ggcctgtggc ctgggggaag gaggacgagg ttctgcctgg      120

atcccagcag taggacgctg tgccatttgg gaacaaagga atagtctgcc tggaatccct      180

gcagatcttg gggccggagg ccagtccaac ccttggagca ggaagaaacg caaagttgtc      240

aagaaccaag tcgagctgcc tcagagccgg cccgcagtag ctgcagactc cgcccgcgac      300

gtgtgcgcgc ttctctgggc cagagcgagc ctgttttgtg ctcgggttaa gagatttgtc      360

ccagctatac catgggccgc actcgggaag ctggctgcgt ggccgctggt gtggttatcg      420

gggctggtgc ctgctactgt gtatacagac tggcttgggg aagagacgag aacgagaaaa      480

tctgggacga agacgaggag tctacggaca cctcagagat tggggttgag actgtgaaag      540

gagctaaaac taacgctggg gcagggtctg gggccaaact tcagggtgat tcagaggtca      600

agcctgaggt gagtttggga ctcgaggatt gtccgggtgt aaaagagaag gcccattcag      660

gatcccacag cggaggtggc ctagaggcca aggccaaggc ccttttcaac acgctgaagg      720

aacaggcaag tgcaaaggca ggcaaagggg ctagggtggg taccatctct gggaacagga      780

cccttgcacc gagtttaccc tgcccaggag gcaggggtgg aggctgccac cccaccagga      840

gtggatctag ggccgggggc agggcaagtg gaaaatccaa gggaaaggcc cgaagtaaga      900

gcaccagggc tccagctaca acatggcctg tccggagagg caagttcaac tttccttata      960

aaattgatga tattctgagt gctcccgacc tccaaaaggt cctcaacatc ctggagcgaa     1020

caaatgatcc ttttattcaa gaagtagcct tggtcactct gggtaacaat gcagcatatt     1080

catttaacca gaatgccata cgtgaattgg gtggtgtccc aattattgca aaactgataa     1140

aaacaaaaga ccccataatt agggaaaaga cttacaatgc ccttaataac ttgagtgtga     1200

acgcagaaaa tcagggcaag attaagacgt acatcagtca agtgtgtgat gacaccatgg     1260

tctgtcgctt ggactcagct gtgcagatgg ctgggctaag actgttaacc aacatgactg     1320

tgactaatca ttaccaacat ttgctttcct attcttttcc agactttttt gctttgttat     1380

tcctgggaaa tcacttcacc aagatacaga ttatgaaact aattataaac tttactgaaa     1440

atccagccat gacaagagag ctggtcagtt gtaaagtacc atcagaattg atttccctct     1500

ttaataaaga atgggataga gagattcttc ttaatatcct taccctattt gagaatataa     1560

atgacaacat aaaaaatgaa gggctcgcat catccaggaa agaattcagc agaagttcac     1620

tttttttctt attcaaagag tctggagttt gtgttaagaa aatcaaagca ctagcaaatc     1680

acaatgatct ggtggtgaaa gtaaaagtcc tgaaagtatt aaccaaactc taatttggag     1740

tctgtcccaa acaatattga gatatttgca gttggtacga tgtgatttgt aaattctttg     1800

tttttcattg tgcgtatatg gtaaagagat cttttcagct gctattttgg aataatgact     1860

atcatatatc ataacagtga ctgatgttgg ttgtaatggt tgggtttagg atgaaccatt     1920

ttaaggatgc caaatgaaat attagtattt gtacacagaa agaatttatt gatttgatct     1980

tattacctag attgagattt tttaatcttt cctctaccta aactgacaat gaattggtta     2040

tacatcatgc ataagctaca cttttatatt agtttatatt tgttattcta agacttgtgt     2100

ttcatcaata aagttgtgtt ttaagcagca gaaaaaaaaa a                         2141


<210>  275
<211>  13416
<212>  DNA
<213>  homo sapiens

<400>  275
ggggcatttc cgggtccggg ccgagcgggc gcacgcgcgg gagcgggact cggcggcatg       60

gcgggctccg gagccggtgt gcgttgctcc ctgctgcggc tgcaggagac cttgtccgct      120

gcggaccgct gcggtgctgc cctggccggt catcaactga tccgcggcct ggggcaggaa      180

tgcgtcctga gcagcagccc cgcggtgctg gcattacaga catctttagt tttttccaga      240

gatttcggtt tgcttgtatt tgtccggaag tcactcaaca gtattgaatt tcgtgaatgt      300

agagaagaaa tcctaaagtt tttatgtatt ttcttagaaa aaatgggcca gaagatcgca      360

ccttactctg ttgaaattaa gaacacttgt accagtgttt atacaaaaga tagagctgct      420

aaatgtaaaa ttccagccct ggaccttctt attaagttac ttcagacttt tagaagttct      480

agactcatgg atgaatttaa aattggagaa ttatttagta aattctatgg agaacttgca      540

ttgaaaaaaa aaataccaga tacagtttta gaaaaagtat atgagctcct aggattattg      600

ggtgaagttc atcctagtga gatgataaat aatgcagaaa acctgttccg cgcttttctg      660

ggtgaactta agacccagat gacatcagca gtaagagagc ccaaactacc tgttctggca      720

ggatgtctga aggggttgtc ctcacttctg tgcaacttca ctaagtccat ggaagaagat      780

ccccagactt caagggagat ttttaatttt gtactaaagg caattcgtcc tcagattgat      840

ctgaagagat atgctgtgcc ctcagctggc ttgcgcctat ttgccctgca tgcatctcag      900

tttagcacct gccttctgga caactacgtg tctctatttg aagtcttgtt aaagtggtgt      960

gcccacacaa atgtagaatt gaaaaaagct gcactttcag ccctggaatc ctttctgaaa     1020

caggtttcta atatggtggc gaaaaatgca gaaatgcata aaaataaact gcagtacttt     1080

atggagcagt tttatggaat catcagaaat gtggattcga acaacaagga gttatctatt     1140

gctatccgtg gatatggact ttttgcagga ccgtgcaagg ttataaacgc aaaagatgtt     1200

gacttcatgt acgttgagct cattcagcgc tgcaagcaga tgttcctcac ccagacagac     1260

actggtgacg accgtgttta tcagatgcca agcttcctcc agtctgttgc aagcgtcttg     1320

ctgtaccttg acacagttcc tgaggtgtat actccagttc tggagcacct cgtggtgatg     1380

cagatagaca gtttcccaca gtacagtcca aaaatgcagc tggtgtgttg cagagccata     1440

gtgaaggtgt tcctagcttt ggcagcaaaa gggccagttc tcaggaattg cattagtact     1500

gtggtgcatc agggtttaat cagaatatgt tctaaaccag tggtccttcc aaagggccct     1560

gagtctgaat ctgaagacca ccgtgcttca ggggaagtca gaactggcaa atggaaggtg     1620

cccacataca aagactacgt ggatctcttc agacatctcc tgagctctga ccagatgatg     1680

gattctattt tagcagatga agcatttttc tctgtgaatt cctccagtga aagtctgaat     1740

catttacttt atgatgaatt tgtaaaatcc gttttgaaga ttgttgagaa attggatctt     1800

acacttgaaa tacagactgt tggggaacaa gagaatggag atgaggcgcc tggtgtttgg     1860

atgatcccaa cttcagatcc agcggctaac ttgcatccag ctaaacctaa agatttttcg     1920

gctttcatta acctggtgga attttgcaga gagattctcc ctgagaaaca agcagaattt     1980

tttgaaccat gggtgtactc attttcatat gaattaattt tgcaatctac aaggttgccc     2040

ctcatcagtg gtttctacaa attgctttct attacagtaa gaaatgccaa gaaaataaaa     2100

tatttcgagg gagttagtcc aaagagtctg aaacactctc ctgaagaccc agaaaagtat     2160

tcttgctttg ctttatttgt gaaatttggc aaagaggtgg cagttaaaat gaagcagtac     2220

aaagatgaac ttttggcctc ttgtttgacc tttcttctgt ccttgccaca caacatcatt     2280

gaactcgatg ttagagccta cgttcctgca ctgcagatgg ctttcaaact gggcctgagc     2340

tataccccct tggcagaagt aggcctgaat gctctagaag aatggtcaat ttatattgac     2400

agacatgtaa tgcagcctta ttacaaagac attctcccct gcctggatgg atacctgaag     2460

acttcagcct tgtcagatga gaccaagaat aactgggaag tgtcagctct ttctcgggct     2520

gcccagaaag gatttaataa agtggtgtta aagcatctga agaagacaaa gaacctttca     2580

tcaaacgaag caatatcctt agaagaaata agaattagag tagtacaaat gcttggatct     2640

ctaggaggac aaataaacaa aaatcttctg acagtcacgt cctcagatga gatgatgaag     2700

agctatgtgg cctgggacag agagaagcgg ctgagctttg cagtgccctt tagagagatg     2760

aaacctgtca ttttcctgga tgtgttcctg cctcgagtca cagaattagc gctcacagcc     2820

agtgacagac aaactaaagt tgcagcctgt gaacttttac atagcatggt tatgtttatg     2880

ttgggcaaag ccacgcagat gccagaaggg ggacagggag ccccacccat gtaccagctc     2940

tataagcgga cgtttcctgt gctgcttcga cttgcgtgtg atgttgatca ggtgacaagg     3000

caactgtatg agccactagt tatgcagctg attcactggt tcactaacaa caagaaattt     3060

gaaagtcagg atactgttgc cttactagaa gctatattgg atggaattgt ggaccctgtt     3120

gacagtactt taagagattt ttgtggtcgg tgtattcgag aattccttaa atggtccatt     3180

aagcaaataa caccacagca gcaggagaag agtccagtaa acaccaaatc gcttttcaag     3240

cgactttata gccttgcgct tcaccccaat gctttcaaga ggctgggagc atcacttgcc     3300

tttaataata tctacaggga attcagggaa gaagagtctc tggtggaaca gtttgtgttt     3360

gaagccttgg tgatatacat ggagagtctg gccttagcac atgcagatga gaagtcctta     3420

ggtacaattc aacagtgttg tgatgccatt gatcacctat gccgcatcat tgaaaagaag     3480

catgtttctt taaataaagc aaagaaacga cgtttgccgc gaggatttcc accttccgca     3540

tcattgtgtt tattggatct ggtcaagtgg cttttagctc attgtgggag gccccagaca     3600

gaatgtcgac acaaatccat tgaactcttt tataaattcg ttcctttatt gccaggcaac     3660

agatccccta atttgtggct gaaagatgtt ctcaaggaag aaggtgtctc ttttctcatc     3720

aacacctttg aggggggtgg ctgtggccag ccctcgggca tcctggccca gcccaccctc     3780

ttgtaccttc gggggccatt cagcctgcag gccacgctat gctggctgga cctgctcctg     3840

gccgcgttgg agtgctacaa cacgttcatt ggcgagagaa ctgtaggagc gctccaggtc     3900

ctaggtactg aagcccagtc ttcacttttg aaagcagtgg ctttcttctt agaaagcatt     3960

gccatgcatg acattatagc agcagaaaag tgctttggca ctggggcagc aggtaacaga     4020

acaagcccac aagagggaga aaggtacaac tacagcaaat gcaccgttgt ggtccggatt     4080

atggagttta ccacgactct gctaaacacc tccccggaag gatggaagct cctgaagaag     4140

gacttgtgta atacacacct gatgagagtc ctggtgcaga cgctgtgtga gcccgcaagc     4200

ataggtttca acatcggaga cgtccaggtt atggctcatc ttcctgatgt ttgtgtgaat     4260

ctgatgaaag ctctaaagat gtccccatac aaagatatcc tagagaccca tctgagagag     4320

aaaataacag cacagagcat tgaggagctt tgtgccgtca acttgtatgg ccctgacgcg     4380

caagtggaca ggagcaggct ggctgctgtt gtgtctgcct gtaaacagct tcacagagct     4440

gggcttctgc ataatatatt accgtctcag tccacagatt tgcatcattc tgttggcaca     4500

gaacttcttt ccctggttta taaaggcatt gcccctggag atgagagaca gtgtctgcct     4560

tctctagacc tcagttgtaa gcagctggcc agcggacttc tggagttagc ctttgctttt     4620

ggaggactgt gtgagcgcct tgtgagtctt ctcctgaacc cagcggtgct gtccacggcg     4680

tccttgggca gctcacaggg cagcgtcatc cacttctccc atggggagta tttctatagc     4740

ttgttctcag aaacgatcaa cacggaatta ttgaaaaatc tggatcttgc tgtattggag     4800

ctcatgcagt cttcagtgga taataccaaa atggtgagtg ccgttttgaa cggcatgtta     4860

gaccagagct tcagggagcg agcaaaccag aaacaccaag gactgaaact tgcgactaca     4920

attctgcaac actggaagaa gtgtgattca tggtgggcca aagattcccc tctcgaaact     4980

aaaatggcag tgctggcctt actggcaaaa attttacaga ttgattcatc tgtatctttt     5040

aatacaagtc atggttcatt ccctgaagtc tttacaacat atattagtct acttgctgac     5100

acaaagctgg atctacattt aaagggccaa gctgtcactc ttcttccatt cttcaccagc     5160

ctcactggag gcagtctgga ggaacttaga cgtgttctgg agcagctcat cgttgctcac     5220

ttccccatgc agtccaggga atttcctcca ggaactccgc ggttcaataa ttatgtggac     5280

tgcatgaaaa agtttctaga tgcattggaa ttatctcaaa gccctatgtt gttggaattg     5340

atgacagaag ttctttgtcg ggaacagcag catgtcatgg aagaattatt tcaatccagt     5400

ttcaggagga ttgccagaag gggttcatgt gtcacacaag taggccttct ggaaagcgtg     5460

tatgaaatgt tcaggaagga tgacccccgc ctaagtttca cacgccagtc ctttgtggac     5520

cgctccctcc tcactctgct gtggcactgt agcctggatg ctttgagaga attcttcagc     5580

acaattgtgg tggatgccat tgatgtgttg aagtccaggt ttacaaagct aaatgaatct     5640

acctttgata ctcaaatcac caagaagatg ggctactata agattctaga cgtgatgtat     5700

tctcgccttc ccaaagatga tgttcatgct aaggaatcaa aaattaatca agttttccat     5760

ggctcgtgta ttacagaagg aaatgaactt acaaagacat tgattaaatt gtgctacgat     5820

gcatttacag agaacatggc aggagagaat cagctgctgg agaggagaag actttaccat     5880

tgtgcagcat acaactgcgc catatctgtc atctgctgtg tcttcaatga gttaaaattt     5940

taccaaggtt ttctgtttag tgaaaaacca gaaaagaact tgcttatttt tgaaaatctg     6000

atcgacctga agcgccgcta taattttcct gtagaagttg aggttcctat ggaaagaaag     6060

aaaaagtaca ttgaaattag gaaagaagcc agagaagcag caaatgggga ttcagatggt     6120

ccttcctata tgtcttccct gtcatatttg gcagacagta ccctgagtga ggaaatgagt     6180

caatttgatt tctcaaccgg agttcagagc tattcataca gctcccaaga ccctagacct     6240

gccactggtc gttttcggag acgggagcag cgggacccca cggtgcatga tgatgtgctg     6300

gagctggaga tggacgagct caatcggcat gagtgcatgg cgcccctgac ggccctggtc     6360

aagcacatgc acagaagcct gggcccgcct caaggagaag aggattcagt gccaagagat     6420

cttccttctt ggatgaaatt cctccatggc aaactgggaa atccaatagt accattaaat     6480

atccgtctct tcttagccaa gcttgttatt aatacagaag aggtctttcg cccttacgcg     6540

aagcactggc ttagcccctt gctgcagctg gctgcttctg aaaacaatgg aggagaagga     6600

attcactaca tggtggttga gatagtggcc actattcttt catggacagg cttggccact     6660

ccaacagggg tccctaaaga tgaagtgtta gcaaatcgat tgcttaattt cctaatgaaa     6720

catgtctttc atccaaaaag agctgtgttt agacacaacc ttgaaattat aaagaccctt     6780

gtcgagtgct ggaaggattg tttatccatc ccttataggt taatatttga aaagttttcc     6840

ggtaaagatc ctaattctaa agacaactca gtagggattc aattgctagg catcgtgatg     6900

gccaatgacc tgcctcccta tgacccacag tgtggcatcc agagtagcga atacttccag     6960

gctttggtga ataatatgtc ctttgtaaga tataaagaag tgtatgccgc tgcagcagaa     7020

gttctaggac ttatacttcg atatgttatg gagagaaaaa acatactgga ggagtctctg     7080

tgtgaactgg ttgcgaaaca attgaagcaa catcagaata ctatggagga caagtttatt     7140

gtgtgcttga acaaagtgac caagagcttc cctcctcttg cagacaggtt catgaatgct     7200

gtgttctttc tgctgccaaa atttcatgga gtgttgaaaa cactctgtct ggaggtggta     7260

ctttgtcgtg tggagggaat gacagagctg tacttccagt taaagagcaa ggacttcgtt     7320

caagtcatga gacatagaga tgatgaaaga caaaaagtat gtttggacat aatttataag     7380

atgatgccaa agttaaaacc agtagaactc cgagaacttc tgaaccccgt tgtggaattc     7440

gtttcccatc cttctacaac atgtagggaa caaatgtata atattctcat gtggattcat     7500

gataattaca gagatccaga aagtgagaca gataatgact cccaggaaat atttaagttg     7560

gcaaaagatg tgctgattca aggattgatc gatgagaacc ctggacttca attaattatt     7620

cgaaatttct ggagccatga aactaggtta ccttcaaata ccttggaccg gttgctggca     7680

ctaaattcct tatattctcc taagatagaa gtgcactttt taagtttagc aacaaatttt     7740

ctgctcgaaa tgaccagcat gagcccagat tatccaaacc ccatgttcga gcatcctctg     7800

tcagaatgcg aatttcagga atataccatt gattctgatt ggcgtttccg aagtactgtt     7860

ctcactccga tgtttgtgga gacccaggcc tcccagggca ctctccagac ccgtacccag     7920

gaagggtccc tctcagctcg ctggccagtg gcagggcaga taagggccac ccagcagcag     7980

catgacttca cactgacaca gactgcagat ggaagaagct catttgattg gctgaccggg     8040

agcagcactg acccgctggt cgaccacacc agtccctcat ctgactcctt gctgtttgcc     8100

cacaagagga gtgaaaggtt acagagagca cccttgaagt cagtggggcc tgattttggg     8160

aaaaaaaggc tgggccttcc aggggacgag gtggataaca aagtgaaagg tgcggccggc     8220

cggacggacc tactacgact gcgcagacgg tttatgaggg accaggagaa gctcagtttg     8280

atgtatgcca gaaaaggcgt tgctgagcaa aaacgagaga aggaaatcaa gagtgagtta     8340

aaaatgaagc aggatgccca ggtcgttctg tacagaagct accggcacgg agaccttcct     8400

gacattcaga tcaagcacag cagcctcatc accccgttac aggccgtggc ccagagggac     8460

ccaataattg caaaacagct ctttagcagc ttgttttctg gaattttgaa agagatggat     8520

aaatttaaga cactgtctga aaaaaacaac atcactcaaa agttgcttca agacttcaat     8580

cgttttctta ataccacctt ctctttcttt ccaccctttg tctcttgtat tcaggacatt     8640

agctgtcagc acgcagccct gctgagcctc gacccagcgg ctgttagcgc tggttgcctg     8700

gccagcctac agcagcccgt gggcatccgc ctgctagagg aggctctgct ccgcctgctg     8760

cctgctgagc tgcctgccaa gcgagtccgt gggaaggccc gcctccctcc tgatgtcctc     8820

agatgggtgg agcttgctaa gctgtataga tcaattggag aatacgacgt cctccgtggg     8880

atttttacca gtgagatagg aacaaagcaa atcactcaga gtgcattatt agcagaagcc     8940

agaagtgatt attctgaagc tgctaagcag tatgatgagg ctctcaataa acaagactgg     9000

gtagatggtg agcccacaga agccgagaag gatttttggg aacttgcatc ccttgactgt     9060

tacaaccacc ttgctgagtg gaaatcactt gaatactgtt ctacagccag tatagacagt     9120

gagaaccccc cagacctaaa taaaatctgg agtgaaccat tttatcagga aacatatcta     9180

ccttacatga tccgcagcaa gctgaagctg ctgctccagg gagaggctga ccagtccctg     9240

ctgacattta ttgacaaagc tatgcacggg gagctccaga aggcgattct agagcttcat     9300

tacagtcaag agctgagtct gctttacctc ctgcaagatg atgttgacag agccaaatat     9360

tacattcaaa atggcattca gagttttatg cagaattatt ctagtattga tgtcctctta     9420

caccaaagta gactcaccaa attgcagtct gtacaggctt taacagaaat tcaggagttc     9480

atcagcttta taagcaaaca aggcaattta tcatctcaag ttccccttaa gagacttctg     9540

aacacctgga caaacagata tccagatgct aaaatggacc caatgaacat ctgggatgac     9600

atcatcacaa atcgatgttt ctttctcagc aaaatagagg agaagcttac ccctcttcca     9660

gaagataata gtatgaatgt ggatcaagat ggagacccca gtgacaggat ggaagtgcaa     9720

gagcaggaag aagatatcag ctccctgatc aggagttgca agttttccat gaaaatgaag     9780

atgatagaca gtgcccggaa gcagaacaat ttctcacttg ctatgaaact actgaaggag     9840

ctgcataaag agtcaaaaac cagagacgat tggctggtga gctgggtgca gagctactgc     9900

cgcctgagcc actgccggag ccggtcccag ggctgctctg agcaggtgct cactgtgctg     9960

aaaacagtct ctttgttgga tgagaacaac gtgtcaagct acttaagcaa aaatattctg    10020

gctttccgtg accagaacat tctcttgggt acaacttaca ggatcatagc gaatgctctc    10080

agcagtgagc cagcctgcct tgctgaaatc gaggaggaca aggctagaag aatcttagag    10140

ctttctggat ccagttcaga ggattcagag aaggtgatcg cgggtctgta ccagagagca    10200

ttccagcacc tctctgaggc tgtgcaggcg gctgaggagg aggcccagcc tccctcctgg    10260

agctgtgggc ctgcagctgg ggtgattgat gcttacatga cgctggcaga tttctgtgac    10320

caacagctgc gcaaggagga agagaatgca tcagttattg attctgcaga actgcaggcg    10380

tatccagcac ttgtggtgga gaaaatgttg aaagctttaa aattaaattc caatgaagcc    10440

agattgaagt ttcctagatt acttcagatt atagaacggt atccagagga gactttgagc    10500

ctcatgacaa aagagatctc ttccgttccc tgctggcagt tcatcagctg gatcagccac    10560

atggtggcct tactggacaa agaccaagcc gttgctgttc agcactctgt ggaagaaatc    10620

actgataact acccgcaggc tattgtttat cccttcatca taagcagcga aagctattcc    10680

ttcaaggata cttctactgg tcataagaat aaggagtttg tggcaaggat taaaagtaag    10740

ttggatcaag gaggagtgat tcaagatttt attaatgcct tagatcagct ctctaatcct    10800

gaactgctct ttaaggattg gagcaatgat gtaagagctg aactagcaaa aacccctgta    10860

aataaaaaaa acattgaaaa aatgtatgaa agaatgtatg cagccttggg tgacccaaag    10920

gctccaggcc tgggggcctt tagaaggaag tttattcaga cttttggaaa agaatttgat    10980

aaacattttg ggaaaggagg ttctaaacta ctgagaatga agctcagtga cttcaacgac    11040

attaccaaca tgctactttt aaaaatgaac aaagactcaa agccccctgg gaatctgaaa    11100

gaatgttcac cctggatgag cgacttcaaa gtggagttcc tgagaaatga gctggagatt    11160

cccggtcagt atgacggtag gggaaagcca ttgccagagt accacgtgcg aatcgccggg    11220

tttgatgagc gggtgacagt catggcgtct ctgcgaaggc ccaagcgcat catcatccgt    11280

ggccatgacg agagggaaca ccctttcctg gtgaagggtg gcgaggacct gcggcaggac    11340

cagcgcgtgg agcagctctt ccaggtcatg aatgggatcc tggcccaaga ctccgcctgc    11400

agccagaggg ccctgcagct gaggacctat agcgttgtgc ccatgacctc cagtgatccc    11460

agggcaccgc cgtgtgaata taaagattgg ctgacaaaaa tgtcaggaaa acatgatgtt    11520

ggagcttaca tgctaatgta taagggcgct aatcgtactg aaacagtcac gtcttttaga    11580

aaacgagaaa gtaaagtgcc tgctgatctc ttaaagcggg ccttcgtgag gatgagtaca    11640

agccctgagg ctttcctggc gctccgctcc cacttcgcca gctctcacgc tctgatatgc    11700

atcagccact ggatcctcgg gattggagac agacatctga acaactttat ggtggccatg    11760

gagactggcg gcgtgatcgg gatcgacttt gggcatgcgt ttggatccgc tacacagttt    11820

ctgccagtcc ctgagttgat gccttttcgg ctaactcgcc agtttatcaa tctgatgtta    11880

ccaatgaaag aaacgggcct tatgtacagc atcatggtac acgcactccg ggccttccgc    11940

tcagaccctg gcctgctcac caacaccatg gatgtgtttg tcaaggagcc ctcctttgat    12000

tggaaaaatt ttgaacagaa aatgctgaaa aaaggagggt catggattca agaaataaat    12060

gttgctgaaa aaaattggta cccccgacag aaaatatgtt acgctaagag aaagttagca    12120

ggtgccaatc cagcagtcat tacttgtgat gagctactcc tgggtcatga gaaggcccct    12180

gccttcagag actatgtggc tgtggcacga ggaagcaaag atcacaacat tcgtgcccaa    12240

gaaccagaga gtgggctttc agaagagact caagtgaagt gcctgatgga ccaggcaaca    12300

gaccccaaca tccttggcag aacctgggaa ggatgggagc cctggatgtg aggtctgtgg    12360

gagtctgcag atagaaagca ttacattgtt taaagaatct actatacttt ggttggcagc    12420

attccatgag ctgattttcc tgaaacacta aagagaaatg tcttttgtgc tacagtttcg    12480

tagcatgagt ttaaatcaag attatgatga gtaaatgtgt atgggttaaa tcaaagataa    12540

ggttatagta acatcaaaga ttaggtgagg tttatagaaa gatagatatc caggcttacc    12600

aaagtattaa gtcaagaata taatatgtga tcagctttca aagcatttac aagtgctgca    12660

agttagtgaa acagctgtct ccgtaaatgg aggaaatgtg gggaagcctt ggaatgccct    12720

tctggttctg gcacattgga aagcacactc agaaggcttc atcaccaaga ttttgggaga    12780

gtaaagctaa gtatagttga tgtaacattg tagaagcagc ataggaacaa taagaacaat    12840

aggtaaagct ataattatgg cttatattta gaaatgactg catttgatat tttaggatat    12900

ttttctaggt tttttccttt cattttattc tcttctagtt ttgacatttt atgatagatt    12960

tgctctctag aaggaaacgt ctttatttag gagggcaaaa attttggtca tagcattcac    13020

ttttgctatt ccaatctaca actggaagat acataaaagt gctttgcatt gaatttggga    13080

taacttcaaa aatcccatgg ttgttgttag ggatagtact aagcatttca gttccaggag    13140

aataaaagaa attcctattt gaaatgaatt cctcatttgg aggaaaaaaa gcatgcattc    13200

tagcacaaca agatgaaatt atggaataca aaagtggctc cttcccatgt gcagtccctg    13260

tccccccccg ccagtcctcc acacccaaac tgtttctgat tggcttttag ctttttgttg    13320

tttttttttt tccttctaac acttgtattt ggaggctctt ctgtgatttt gagaagtata    13380

ctcttgagtg tttaataaag tttttttcca aaagta                              13416


<210>  276
<211>  1403
<212>  DNA
<213>  homo sapiens

<400>  276
gcggccgcca ccccaccatg ctcaagcgct gcggccggcg cctgctgctg gcgctggcgg       60

gcgcgctgct cgcctgcctg ctggtgctca ccgccgaccc gccgccgcct ccactgcccg      120

ccgagcgcgg ccggcgcgcg ctgcgcagcc tggcgggccc cgcgggggct gccccggcgc      180

ccgggctggg ggcggcggcg gcggcgcccg gggcgctggt ccgcgacgtg cacagtctgt      240

ccgagtactt cagcctgctc acccgcgcgc gcagagatgc gggcccgccg cccggggctg      300

ccccccgccc cgccgacggc cacccgcgcc ccctggccga gccgctcgcg ccccgagacg      360

tcttcatcgc tgtcaagacc accaaaaagt tccaccgcgc gcgcctcgac ctgctgctgg      420

agacctggat ctcgcgccac aaggagatga cgttcatctt cactgacggg gaagatgagg      480

ccctggccag gcacacgggc aacgtggtca tcacaaactg ctcggccgcc cacagccgcc      540

aggcgctgtc ctgcaagatg gccgtggagt atgaccgctt catcgagtcc ggcaggaagt      600

ggttctgcca cgtggacgat gacaactacg tcaacctgcg ggccctgctg cggctgctgg      660

ccagctaccc gcacacgcgg gacgtctacg tcggcaagcc cagcctggac aggcccatcc      720

aggccatgga gcgggtcagc gagaacaagg tgcgtcctgt ccacttctgg tttgccacgg      780

gcggcgctgg cttctgcatc agccgtgggc tggctctgaa gatgagcccg tgggccagcg      840

ggggtcactt catgaatacg gctgagcgga tccggctgcc tgatgactgc accatcggct      900

acatcgtgga ggccctgctg ggtgtgcccc tcatccgcag cggcctcttc cactcccacc      960

tggagaacct gcagcaggtg cccacctcgg agctccacga gcaggtgacg ctgagctacg     1020

gtatgtttga aaacaagcgg aacgccgtcc acgtgaaggg gcccttctcg gtggaggccg     1080

acccatccag gtggggaaac tgaggcacgg agcagctgat gcccaaggtc cagcagccat     1140

gctggtgggc tggggaggcg ctcagactcc aagccaggca ggccgtgggt ccggccgccc     1200

cacagctggt aatgctgcac ctccctctcc tgtgatgtgg ccccaggccc cgaccccgct     1260

caggggtggt gggaagagtc ctggagagca ggagcagtgc cggagccccc actgcagctg     1320

gtcccagccc ctgcagagat ccagacgctt gttttttaaa tacagcagct ctgcggtgct     1380

tttccttcct caaaaaaaaa aaa                                             1403


<210>  277
<211>  2932
<212>  DNA
<213>  homo sapiens

<400>  277
ggggagccct aggctcggcg ctgccggagg ggcccgagcc gagccgcctg cgccccggcc       60

gggcagcgcc gggcccgctt cccgcggggc cacgccctgt caaactttgt tgcggcggct      120

agcgcagcgg gcccgcaagc gggcgggagg ggcgccgggc cgggccgggc agggcgcggg      180

cggctagggg ctccgagagc ggcggccccg gcccgcggcc ccaccatgcc ccagctcggc      240

ggcgggggcg gcggcggcgg cggcggcagc gggggaggcg gcggctccag cgccggggcg      300

gccggcggag gggacgacct cggggcgaac gacgagctga tccccttcca ggacgagggg      360

ggcgaggagc aggagccgag cagcgatagc gcctcggcgc agcgggacct agacgaggtc      420

aagtcgtccc tggtcaacga gtcggagaac cagagcagca gctcggactc ggaggcggag      480

aggcgcccgc agcccgtccg ggacactttc cagaagccgc gggactattt cgccgaagtg      540

agaaggcctc aggacagcgc gttctttaaa ggacccccgt accctgggta ccccttcctg      600

atgatcccgg acctgagcag cccgtacctc tccaacggac ccctgtctcc cggaggagcg      660

cgcacctacc tgcagatgaa atggcccctc ctcgatgtcc cctccagcgc cacagtcaag      720

gacacgaggt caccatctcc agcacacttg tctaataaag ttcctgtcgt tcagcacccg      780

catcacatgc atccgctgac tcccctcatc acctacagca atgaccactt ctcccccggc      840

tcccctccca cccacctctc cccagagatc gatccaaaga caggaatccc ccggccccct      900

cacccatccg agctgtcacc gtattaccca ctctctcccg gagctgtcgg acaaatcccc      960

caccccctcg gctggctcgt cccacagcaa ggccagccca tgtactccct tcctcccggt     1020

ggcttccggc acccttaccc cgccctcgcc atgaacgcct cgatgtccag cctggtctcc     1080

agtcggttct ctcctcacat ggtggctcct gcccaccctg gcctgcccac ctcagggatc     1140

ccccaccctg ccatcgtctc ccccatcgtc aagcaggaac cggcaccccc cagcctgagc     1200

cctgcagtga gcgtgaaatc accagtcacc gtgaaaaagg aggaggaaaa gaagccccac     1260

gtgaagaagc ctctgaatgc cttcatgttg tatatgaagg agatgagggc caaggtggtg     1320

gctgagtgca ccctgaagga aagtgcagcc attaaccaga tccttggaag aaagtggcac     1380

aacctgtctc gagaagaaca ggccaagtac tacgagctgg cccggaagga gcggcagctt     1440

cactcgcagc tctacccaac ctggtcagcc cgggacaact atggtaagaa aaagaagagg     1500

aagagagaaa agcagctgtc ccagacacag tcacagcagc aagtccagga ggcagagggt     1560

gccctggcct ccaagagcaa gaagccatgt gttcagtacc tgccccccga gaagccctgt     1620

gacagccctg cctcctccca cgggagcatg ctggactccc cggccactcc ctctgcagct     1680

ttggcctcac cagctgcccc tgctgccacc cattcggagc aagcccagcc cctctccctc     1740

accaccaaac cagaaacccg ggcccagctg gctctccact ctgccgcctt cctgtcggct     1800

aaggctgcag cctcctcctc tgggcagatg ggcagccagc ctcccctcct gtcccggccc     1860

ctcccccttg ggtccatgcc cacagctctg ctggcctctc ccccgtcctt ccccgccacg     1920

ctccatgccc accaggccct cccggtgcta caggcccagc ctctttccct ggtcaccaag     1980

tctgcccact aagctccccc cgacccctgc aggctgtcac atgactcatt gagtagtaat     2040

gattcagaag aaaaagaaaa aggagacttt attggtcaat atttgaccac tctggactgt     2100

tctgtaaagt ggctggtaac aacagcactt tacagtttgt agatgtaacc agtagctgat     2160

cttaaggctt ttttaaaaaa caaaacaaaa caacaaaaaa aaatctttat aagaaagaga     2220

actgaaaagt agcgtgctat tcgtcctgta ggtgctgtgg tggatggacc tgggcagagg     2280

gcacttctct ctcttacctc tcttgcactt tctgtctcct gtctcttctc gcccctgccg     2340

cctgccccag cttccccgac tccatctgca gctctgccat tgtgacattt cctgttaccc     2400

agcccaagtt ttcatcgtct gctcaatacc gtgggttctt cttcgtcctc tgtcctctgc     2460

ccagtgtgag gccatcacca tgtgagaaga catcttggcc tgatttgctg ccaccagcgt     2520

cccctccctc agtgggcccg aactcgccag ccccagcttt cagtggagaa agcggtcctc     2580

tgaaatggtt tcctcccaac ccccgcattt aaagggactc aaggtgcctg ccacttcctc     2640

agcgaagaag tctgtgttcc tccccgtcct tgccagtggc gatcatccct tcacaatccc     2700

agagtggcag gcgggaccgg ccccatggtc tggctcctgt cacctgggtc cgtgccagca     2760

caatctgcca aagttctaga gaccctgttc ccttccccat cacctcacat gcttcttctg     2820

tgtgtatttc tttttgtttt tatggttttt ggagcaattt aaactcccag ttgtttattt     2880

tcacaaaaga aaataaaatt gcagttgcaa gaccttttaa aaaaaaaaaa aa             2932


<210>  278
<211>  3932
<212>  DNA
<213>  homo sapiens

<400>  278
tcccagacag aacctactat gtgcggcggc agctggggcg ggaaggcggg agctgggggc       60

gctgggggcg ctgcggccgc tgcggccgct gcagccgctg cagcgccagg gtccacctgg      120

tcggctgcac ctgtggagga ggaggtggat ttcaggcttc ccgtagactg gaagaatcgg      180

ctcaaaaccg cttgcctcgc aggggctgag ctggaggcag cgaggccgcc cgacgcaggc      240

ttccggcgag acatggcagg gcaaggatgg cagcccggcg gcagggcctg gcgaggagcg      300

cgagcccgcg gccgcagttc ccaggcgtct gcgggcgcga gcacgccgcg accctgcgtg      360

cgccggggcg ggggggcggg gcctcgcctg cacaaatggg gacgaggggg gcggggcggc      420

cacaatttcg cgccaaactt gaccgcgcgt tctgctgtaa cgagcgggct cggaggtcct      480

cccgctgctg tcatggttgg ttcgctaaac tgcatcgtcg ctgtgtccca gaacatgggc      540

atcggcaaga acggggacct gccctggcca ccgctcagga atgaattcag atatttccag      600

agaatgacca caacctcttc agtagaaggt aaacagaatc tggtgattat gggtaagaag      660

acctggttct ccattcctga gaagaatcga cctttaaagg gtagaattaa tttagttctc      720

agcagagaac tcaaggaacc tccacaagga gctcattttc tttccagaag tctagatgat      780

gccttaaaac ttactgaaca accagaatta gcaaataaag tagacatggt ctggatagtt      840

ggtggcagtt ctgtttataa ggaagccatg aatcacccag gccatcttaa actatttgtg      900

acaaggatca tgcaagactt tgaaagtgac acgttttttc cagaaattga tttggagaaa      960

tataaacttc tgccagaata cccaggtgtt ctctctgatg tccaggagga gaaaggcatt     1020

aagtacaaat ttgaagtata tgagaagaat gattaatatg aaggtgtttt ctagtttaag     1080

ttgttccccc tccctctgaa aaaagtatgt atttttacat tagaaaaggt tttttgttga     1140

ctttagatct ataattattt ctaagcaact agtttttatt ccccactact cttgtctcta     1200

tcagatacca tttatgagac attcttgcta taactaagtg cttctccaag accccaactg     1260

agtccccagc acctgctaca gtgagctgcc attccacacc catcacatgt ggcactcttg     1320

ccagtccttg acattgtcgg gcttttcaca tgttggtaat atttattaaa gatgaagatc     1380

cacataccct tcaactgagc agtttcacta gtggaaatac caaaagcttc ctacgtgtat     1440

atccagaggt ttgtagataa atgttgccac cttgtttgta acagtgaaaa attgaaaaca     1500

acctggaagt ccagtgatgg gaaaatgagt atgtttctgt cttagattgg ggaacccaaa     1560

gcagattgca agactgaaat ttcagtgaaa gcagtgtatt tgctaggtca taccagaaat     1620

catcaattga ggtacggaga aactgaactg agaaggtaag aaaagcaatt taaagtcagc     1680

gagcaggttc tcattgataa caagctccat actgctgaga tacagggaaa tggagggggg     1740

aaagctggag tattgatccc gcccccctcc ttggttgtca gctccctgtc ctgtgtgtgg     1800

gcggaacata gtccagctgc tctatagcaa gtctcaggtg tttgcagtaa gaagctgctg     1860

gcatgcacgg gaacagtgaa tgccaaacac ttaaagcaat tcgatgttta agtatgtaag     1920

ttcttttttt tttagacagc gtttcgctct tgttgcccag gctagcatgc aatggtgtga     1980

cctcggctta ctgcaacctc cgccttccca gattcaagcg attctcctgc ctcaggctcc     2040

caagtagcta ggaccaggtg cgcgccacca cgcccggcta atttttgtat tttgtatttt     2100

tagtagagat ggggtttcac catgttggtc aggctagtct cgaactcgtg accgcaagcg     2160

attcacccac ctcagcctcc caaagtgctg ggattaccgg cttgagccac cacacccggc     2220

acatcttcat tctttttatg tagtaaaaag tataaggcca cacatggttt atttgaagta     2280

ttttataatt taaaaaaata cagaagcagg aaaaccaatt ataagttcaa gtgagggatg     2340

atggttgctt gaaccaaagg gttgcatgta gtaagaaatt gtgatttaag atatatttta     2400

aagttataag tagcaggata ttctgatgga gtttgacttt ggttttgggc ccagggagtt     2460

tcagatgcct ttgagaaatg aatgaagtag agagaaaata aaagaaaaac cagccaggca     2520

cagtggctca cacctgtaat cccagcgctt tgggaggcta aggcaggcag atcacttgag     2580

accagcttgg gcaacatggc aaagccccat ctctacaaaa aacacaaaaa ttagctgggc     2640

attgtggcgc acacctgtat tcccatctag tcaggaagct gagatggaag aattaattga     2700

gcccacgagt tcaaggctgc agtgagtcgt gattgtgcca ctgcactcca gccggggtga     2760

cagaagagac cttgtctcga aaaggaatct gaaaacaatg gaaccatgcc ttcataattc     2820

tagaaagtta ttttcaactg ataaatctat attcacccaa ataatcaagg gtgaaggtaa     2880

aataatacat ttttagacaa gcaaagactc aggggttacc tccatgtgcc ctttttaggg     2940

aagctgttgg agaaaatact ccagcaaaat gaaggagtac acaaaccaga gaatgacatg     3000

aatccagcaa ataggatcca acacaggcaa tattccagct atggagctag ctttaaaaag     3060

gaacagtaaa aatattaatc ggttagctgg gtggaatggc ccatgcctgt agtcccagct     3120

actcaggagg ctcagcagca ggacgacttg agcccaagag ttccagacca gcctggccac     3180

cttagtgaga tcccttctct taaaaataat aacttattgc cagatttggg gcatttggaa     3240

agaagttcat tgaagataaa gcaaaagtaa aaaaaaaaaa aaaaaaaaca aggggaaagg     3300

gttggttagg caatcattct agggcagaaa gaagtacagg ataggaagag cataatacac     3360

tgtttttctc aacaaggagc agtatgtaca cagtcataat gatgtgactg cttagcccct     3420

aaatatggta actactctgg gacaatatgg gaggaaaagt gaagattgtg atggtgtaag     3480

agctaaatcc tcatctgtca tatccagaaa tcactatata atatataata atgaaatgac     3540

taagttatgt gaggaaaaaa acagaagaca ttgctaaaag agttaaaagt cattgctctg     3600

gagaattagg agggatgggg caggggactg ttaggatgca ttataaactg aaaagccttt     3660

ttaaaatttt atgtattaat atatgcattc acttgaaaaa ctaaaaaaaa acaataattt     3720

ggaaaaaccc atgaaggtaa ctaacggaag gaaaaactaa gagaatgaaa agtatttgcc     3780

tctggaaaga acaactggca ggactgttgt tttcattgta agacttttgg agccatttaa     3840

ttgtacttaa ccattttcat ctatttcttt aataagaaca attccatctt aataaagagt     3900

tacacttgtt aataagtaaa aaaaaaaaaa aa                                   3932


<210>  279
<211>  5217
<212>  DNA
<213>  homo sapiens

<400>  279
gggggcgttg tctgggggcg gggctccggc cgcctctgac gagtcccgga tttaccaggg       60

ccggtgggat cccctcgggc tcccgcctta gcatgctggc cgggacatct ggtgaacatg      120

gcctctgcta ctgcggcagc agcacgacgg ggcctcggcc gggctctccc tctcctctgg      180

cgtggctacc agaccgagcg gggcgtttac ggctaccggc cgaggaagcc cgagagccgc      240

gagccccagg gcgccctgga gcgcccccca gttgatcatg gccttgccag gttggtgaca      300

gtatattgtg agcatggtca taaagctgcc aaaatcaacc ccctcttcac cggacaagcc      360

ctgctggaga atgtgcctga aatccaagcc ctggtgcaga cactgcaggg acccttccac      420

acggcaggat tattgaacat ggggaaggaa gaggcctcac ttgaggaagt gttagtctat      480

ctcaatcaaa tctactgtgg gcagatttct attgaaacct cccaacttca gagccaggat      540

gagaaagact ggtttgccaa gcggtttgag gaactgcaaa aggagacgtt taccacagaa      600

gagcgaaaac atctgtcgaa actaatgctg gaatctcagg agtttgacca ctttctggcc      660

accaagttct cgacagtgaa gcgatatgga ggcgaagggg ctgaaagcat gatgggcttt      720

ttccacgagc tgctgaaaat gtcggcctac agcgggatca ctgatgtcat tattgggatg      780

ccccatagag ggaggctgaa tttattgaca ggccttctgc agttccctcc agagctgatg      840

ttccgtaaaa tgcgaggctt aagtgaattt ccagagaatt tctcagccac tggagacgtc      900

ctgtctcacc tgacctcctc tgtggacctg tactttgggg cgcaccatcc cctccatgtg      960

acaatgttgc ccaatccctc gcacctggag gccgtcaacc ccgtggccgt gggcaaaact     1020

cgcggcaggc agcagtctcg ccaagacggc gattactctc cagacaactc agcccagccg     1080

ggggacaggg tcatttgctt acaggtccat ggtgatgctt ctttctgtgg tcaagggatt     1140

gttcctgaaa cattcacgct gtccaatctc ccacatttca gaattggtgg gagtgtgcat     1200

ttgattgtta ataaccagct gggttacacc actccagctg aaagaggaag gtcttcttta     1260

tactgcagtg atattgggaa gcttgtgggc tgtgccatca tccatgtcaa tggagacagc     1320

ccagaggaag tggtccgtgc cacacgactg gcttttgaat accaacgcca gttccgcaag     1380

gatgtgatta ttgatctgtt gtgctacagg cagtggggcc acaatgagct ggatgagcca     1440

ttctacacca accccatcat gtacaaaatc atcagagctc gaaagagcat tccagacaca     1500

tatgcagagc acctcattgc tggcggactc atgacgcagg aggaggtgtc tgaaataaaa     1560

tcctcctact atgccaagtt gaatgatcac ttaaataaca tggcccacta caggccccct     1620

gccctgaacc tgcaggccca ctggcagggc ctggctcagc cagaagcgca aatcaccacc     1680

tggagtacag gtgtgcccct cgacctcctg cggtttgttg gcatgaagtc tgtagaggtg     1740

ccaagagagc tgcagatgca cagtcacctg ctgaagacac atgttcagtc cagaatggag     1800

aagatgatgg acggaatcaa gctagactgg gccaccgcgg aagctcttgc cttgggttct     1860

ttacttgctc aaggttttaa tgttcgtcta agtggccaag atgttggtcg tggaactttc     1920

agtcagaggc atgcaatcgt ggtttgccag gagacggatg acacctacat ccccctgaac     1980

catatggacc caaatcagaa ggggtttcta gaggtcagca acagccccct gtcagaagag     2040

gccgtcctgg gattcgaata tgggatgagc attgagagcc caaagttact gcccctgtgg     2100

gaggcacagt ttggcgattt cttcaatggt gcccagatca tctttgacac attcatctct     2160

ggaggagagg ccaagtggct cctacaaagc ggcatcgtca tcctccttcc acatggctac     2220

gatggggctg ggccagacca ctcatcctgt cgaatagagc gtttcctgca gatgtgtgac     2280

agtgcggaag agggggtgga cggagacact gtgaacatgt ttgtggttca cccaacaact     2340

cctgcacagt atttccactt gcttaggaga cagatggtcc ggaacttcag aaaaccactc     2400

attgttgctt cccctaagat gttactcagg ctcccggcag ccgtgtcaac tcttcaagaa     2460

atggcaccag gaacaacatt taacccggtc attggtgatt catctgtgga tccaaaaaag     2520

gttaagaccc tcgtgttctg ctccggcaaa catttctact ccctggtgaa acaaagagaa     2580

tctctggggg ccaagaagca tgactttgcc atcatccgag tagaggaact ctgccccttc     2640

ccgttggatt ctttacagca agagatgagc aaatacaaac atgttaaaga tcatatttgg     2700

agtcaggagg aacctcagaa catgggtccg tggtcgtttg tttctccaag gtttgaaaag     2760

cagctggcct gcaagctccg tctggtgggc cggccccctt tgccagtacc cgctgtagga     2820

attggcacag ttcacttgca ccagcatgaa gatatcctcg ccaagacctt cgcttgatga     2880

tgacttttga agaaacacta tttctcttta agaaaatggc cattaaggcc gggtggggtg     2940

gcacatgcct gtaatcccag cactttggga ggccaaggct ggtggatcac ctgaggtcag     3000

gagttcgaga ccagcctggc caacacggtg aaaccccgcc tctactaaaa atacaaaaaa     3060

tagccgggtg tggtggtggg cacctgtgat cccagcttcc tgggaggctg aggcaagaga     3120

atcgcttgaa tctgggaggc ggaggttgca gtgagccagg atcacaccat tgctgtccag     3180

cctgggtgac agagcaagac tgcgtttcaa aaaaaaaaaa aaaaaaaccc attaaaagag     3240

gcctccttcc tccactctct caacccctct gttgggtaac atgaaaagac tgtattcctc     3300

taagatgttg ggattgatat acgtgattta atctgcaata ggtggaataa ccaggggaac     3360

tggttatgaa tatgtgaatg caaccagcaa atttatcctt gaaggtgtga tggtagaaat     3420

aggaaaacaa caaaagaaaa acaataacaa aaaaagaaag tgtgatggct gggtgcagtg     3480

gctcacgcct gtaatcccag cactttggga ggcttaggcg gctggatcac ctgaggtcag     3540

gagttcaaga ccagcctggt caacgtggtg aaacgccgtt tctactaaaa atatgaaaat     3600

tagttgggtg tggtggcatg cgcttgtagt ctcagctact ccggaggctg aggcaggaga     3660

attgcttgaa cctggaaggc agaggttgca gtgagccgaa atggcgccac tgtactccaa     3720

cctgggcgac agagcaagac tccatctcat aaattaaaag gaaagtatga tagtgttatg     3780

gattttagct ctgagtgagc tggaaaacta ggtcattatc tagatgattt cagacttgac     3840

cctaattgac catatatgac caggaaacac ttctgagttt acagctccgt ggagatgacc     3900

tcaacactgc ctcttgattt gtttgatgca tgtcactttc attaattttc cccctccttt     3960

ttgaaagtcc tgtggcagta ctaatatttt cattttatgt aatctctggt gctgctttcc     4020

agtcactgta tgaagtgtct ccccaacact agcaaatcta ggtcctacta aatacaaatc     4080

tctgggtgga tgatcttcta gtactgtatt tttaaattaa ggagttttag ttataatgaa     4140

attgatttgt agtctgtttt gccgtaaact tgtttttctt taaattgttc ttacagtgat     4200

atcttactat ttttaactgt ctggggtttc tgatatgggg atttcagccc ctggttaatc     4260

agtcttgtcc ctacaagtcc ctgatgcagt atgtttattt gtgatgttta aagaacattt     4320

cttggctggg cgctgcggct tgcgcctgta atctcagcac tttgggaggc tgagatgggt     4380

ggatcacctg aggttgggag ttcgagacca gcctgacaaa acatagtgaa accccgtctc     4440

tactaaaaat acaaaaatta gctgggcgtg gtggtgggtg tctgtaatcc cagctattcg     4500

ggaggctgag gcaggagaat cgcttgaacc caggaggtgg aggttgcagt gagctgagat     4560

cctgccactg cactccagtc tgggtgacag agcaagactc catctcaaaa aataaataaa     4620

tagaaagaga gagagaggaa aaaaaaagaa aagaacactt ctttatttga gggactttcc     4680

caacaccagg tgcttgggga tttcttagag atcaccaacc gactccctca ctgtgaaatt     4740

aaaccaagta ctggaaacgt aactaaacag cgaaccatgt agcttcacct gactcagtgc     4800

tgggggcctc taccatctac tgtgcttgtg tcatgatgct ttttctctga agtggtgtgg     4860

gaagtaccag gggactggca gaagcccagg ccctctctac ttttaccagc aactgatcat     4920

gtctttcaga atccatgtac atataggctg ttctagccac agtggtagat ttatgattca     4980

catccgaaag tgtgccttag ttatcaattt aacatttctc tagtattcat atcccttttc     5040

ttaccatata cctcagtgta tccttcctgt gtcaagcctt ataaatcatg taatttagtg     5100

ccactcatgt aaatcagtaa aatcacaaag gtctatttaa tgaaaacgat ttaccaatgt     5160

tgtttttttt taacaagaaa aaaaataaaa gcacattgtc attttttttc ctcagga        5217


<210>  280
<211>  4709
<212>  DNA
<213>  homo sapiens

<400>  280
ggcgcgttcc ttcctcttcc tctctcctct ccggccccgc cttcccttcc ctccgcccac       60

ctccctgaag cggagccgcc gtcgccacca gcgccgtcat gtcggccccc gccgggtcct      120

ctcacccggc cgccagcgcc cggatcccgc ccaagttcgg cggagcggcc gtctcaggag      180

ccgcagcgcc cgcgggcccg ggtgcgggcc cggcgccgca ccagcagaac ggtccagccc      240

agaatcaaat gcaggttcca tctggatatg gattgcatca tcaaaactat attgctccct      300

caggacatta ctctcaagga cctgggaaaa tgacctcatt gccattggat acccagtgtg      360

gtgattacta ctctgctctc tatacagtac caacacaaaa tgtgactcct aacacagtga      420

accagcaacc aggagcacag cagttgtaca gcaggggtcc tcctgcccct catattgtgg      480

gatccactct aggatctttc caaggtgctg catcgtcagc atcccatttg catacgagtg      540

cctcccaacc atactcctct tttgtgaatc actacaatag tccagccatg tactctgcca      600

gctcttctgt tgcgtctcag ggatttccct ctacttgtgg tcattatgct atgtcaactg      660

tttctaatgc cgcgtatcct agtgtttcat atccctctct gcctgctggt gatacatatg      720

ggcaaatgtt tacctcacag aatgctccga ctgttaggcc agttaaagat aattcattct      780

ctggtcaaaa tacagctatc agccatccat cgccacttcc acctctacca tcacaacagc      840

accaccagca gcaaagtctt tcaggataca gtactctaac gtggtcatct ccaggccttc      900

catcgactca agacaatctc atccgaaacc acacaggatc cctggctgta gcgaacaaca      960

acccaaccat tactgttgca gattctttat cctgtcctgt tatgcaaaat gttcagcctc     1020

ccaagtccag cccagtggta tccactgttt tatcaggatc ctcaggatcc tcatcaacaa     1080

gaacacctcc cactgcaaat cacccagttg agcctgtgac ctcagttaca cagccatcag     1140

agctattaca acaaaaaggc gtgcagtatg gtgaatatgt taataaccaa gctagctccg     1200

caccaactcc cttgtcatca acttccgatg atgaggaaga ggaggaggag gatgaggaag     1260

caggtgttga cagctcttct accacaagca gtgcttctcc aatgcccaac agttatgatg     1320

ccctggaagg aggcagttac ccagatatgc tttcttcatc agcaagcagt cctgctcctg     1380

atcccgcccc tgaacctgat cctgcttctg ctccagctcc agcttcagct ccagctcctg     1440

tcgtccctca gccttcaaaa atggctaagc cttttggcta tggctatcca acacttcagc     1500

ctggttatca gaatgctaca gcaccactta tttctggagt acagcccagt aacccggtat     1560

attctggatt ccagcagtat cctcaacagt atcctggtgt gaaccagcta tcctccagta     1620

taggaggatt gagtcttcag agttctccac aaccagaaag cctgagacct gtaaacctta     1680

ctcaggagag gaatatttta cctatgactc ctgtttgggc tcctgtacct aacttgaatg     1740

cagacctcaa aaaattaaac tgtagcccag attcatttcg gtgtactttg acaaatattc     1800

cacagacaca ggctttactg aataaagcta agcttccttt aggattgttg ttacatccct     1860

tcagagacct aacgcaatta ccagtgataa catcaaatac cattgtgagg tgccgatcct     1920

gtcgaacgta tattaacccc tttgtatcct tcattgatca acgtagatgg aaatgcaatt     1980

tgtgctatag agtaaacgat gttcctgaag aatttatgta taaccccctt acccgatctt     2040

atggagagcc tcataaacga ccagaagttc agaattcaac tgtggagttc attgcttctt     2100

cagattacat gctgcgtcct cctcaacctg cagtttactt gtttgtttta gatgtgtctc     2160

ataatgcagt ggaagctgga tatttgacaa ttttgtgcca gtcactccta gaaaatctag     2220

acaagcttcc tggagattca cgaacaagaa taggattcat gacctttgat agcactattc     2280

atttctacaa tttacaagaa ggattatcac agcctcaaat gttgattgtg tctgatatag     2340

atgatgtttt tctacctaca ccggatagtt tacttgtgaa tctatatgaa agtaaagagc     2400

ttataaaaga cttactgaat gcattaccaa acatgttcac caatacaaga gaaacacaca     2460

gtgcccttgg tcctgcactt caggctgcct ttaaattaat gtctccaaca ggtggccgtg     2520

tgtctgtatt tcagacacag ttaccttcct tgggtgcagg acttctgcaa tccagagaag     2580

atcctaatca gagatcaagt acaaaggtgg tacaacatct tggccctgca actgattttt     2640

ataagaaact tgcattagat tgctcgggac agcaaactgc agtggatttg ttccttttaa     2700

gttcacagta ttctgatctt gcttctctag cttgcatgtc caagtattct gcagggtgca     2760

tctattatta tccatcattc cactatactc acaatccttc acaagcagaa aagttacaaa     2820

aagacctaaa acggtatctc acaagaaaaa ttgggtttga agctgttatg agaataaggt     2880

gtactaaagg tctttcaatg cacacttttc acggtaactt ctttgtccgt tctactgatt     2940

tgttatccct tgccaacatc aatcctgatg ctggatttgc ggtgcagttg tcaattgaag     3000

aaagtttaac agatacttcc ttagtatgtt ttcaaacagc cctattatat acatcaagca     3060

aaggtgagcg gagaattaga gtacatacac tttgtttgcc agtggtaagt tcactagcag     3120

atgtatatgc gggagtggat gtacaagctg ccatctgcct tctggcaaac atggctgtgg     3180

atcggtccgt ttcatcaagt ctgtcagatg caagagatgc cttagtgaat gctgtagtgg     3240

actcattgtc tgcatatggc tcaactgtct caaatttaca gcactctgca ttgatggcgc     3300

ccagctccct caagttgttt cctctctatg ttttggccct tctcaaacag aaagcattta     3360

gaacgggtac aagcacacgg ctggatgatc gtgtatatgc catgtgtcag ataaagtctc     3420

agccacttgt tcatctaatg aaaatgattc atcccaactt atacaggata gacagattga     3480

cagatgaggg tgcagtacat gttaatgaca ggattgtacc acagccacct cttcaaaaat     3540

tgtctgcaga gaagctgaca agagaaggtg ctttccttat ggactgtggc tctgtttttt     3600

acatttgggt tgggaaaggc tgtgacaata acttcataga ggatgtgctt ggatatacta     3660

attttgcatc aataccacag aaaatgacac atcttccaga gctagataca ctttcatcag     3720

aaagagccag atccttcata acttggctta gagacagcag accattaagt ccaatccttc     3780

acatagtaaa agatgagagt cctgccaaag cagaattttt tcagcatttg attgaagacc     3840

ggacagaggc tgcattttct tactatgaat ttttgcttca tgttcagcag cagatttgta     3900

agtgaagtag aataaaattg aataagaaaa agatctataa cctaggtaaa gcataatctg     3960

tcagagaagc gcgtgagaaa tttgaaatga aggcatttgt taatacaaga tgcaacgcac     4020

agcactctgt ctgaggcttt ggtaaaaagt aaaggggaag aaagaacttg acagatcttt     4080

ttcaactcaa attaatggta acgatgatgc tgtttcacca agtatatttt gaattggttt     4140

ctacacattt ccagtagtat ggcagtacag tgctctgttc attgcaagct ggcaaattta     4200

tgtagctatg tggaatgata tgtcataatg taaaattaga taaattcttt tttcttataa     4260

ttaatataac atttctggac ttgaactctg gcaagagatg ccaaaaggca ttggtaccgt     4320

gttatttgtt tatatgaatt actttttaac aaggaatgtt tcttattcat taaatgaatt     4380

caacattttc tctgtaaaaa caatagagtt tcagtacatg aactatagaa aaaaatctat     4440

atataatgta cataaatgtt acatttgtaa agaaaatgta aaaatgtaac tatagcatat     4500

gaattgctta aactgtgctg cattgttgga tgacaactct ttttgtcaca gttagagaat     4560

gaggttgact aatgcatatt atgaattgag tccacaaagg aacacaaaac tctttgtaat     4620

tctgttaaat cttttatgta gatttattta tgatcagcct actaattaaa actatttcgc     4680

ttgacagtaa aaaaaaaaaa aaaaaaaaa                                       4709


<210>  281
<211>  1352
<212>  DNA
<213>  homo sapiens

<400>  281
cgtgaagtgg gcggagcgag cgatttgaac gcgagcggcg cggacttctg ccaagcaccg       60

gctcatgtga ggctcgcggc acagcgttct ctgggctccc cagaagccag cctttcgctc      120

ccggacccgg cagcccgagc aggagccgtg ggaccgggcg ccagcaccct ctgcggcgtg      180

tcatgggccc gcgccgccgg agccgaaagc ccgaggcccc gaggaggcgc agcccgagcc      240

cgaccccgac ccccggcccc tcccggcggg gcccctcctt aggcgcttcc tcccatcaac      300

acagtcggcg gagacaaggt tggctaaagg agatccgaaa gcttcagaag agcacacacc      360

tcttgataag gaagctgccc ttcagccgcc tggcagcaga agcatttcta gttcatctct      420

ttgaggacgc ctatctcctc accttacatg caggccgagt tactctcttc ccaaaggatg      480

tgcaactggc ccggaggatc cggggccttg aggagggact cggctgagct cctgcaccca      540

gtgtttctgt cagtctttcc tgctcagcca ggggggatga taccggggac tctccagagc      600

catgactaga tccaatggat tctgcgatgc tgtctggact ttgctgtctc tgaacagtat      660

gtgtgtgttg ctttaaatat ttttcttttt tttgagaagg agaagactgc atgactttcc      720

tctgtaacag aggtaatata tgagacaatc aacaccgttc caaaggcctg aaaataattt      780

tcagataaag agactccaag gttgacttta gtttgtgagt tactcatgtg actatttgag      840

gattttgaaa acatcagatt tgctgtggta tgggagaaaa ggctatgtac ttattatttt      900

agctctttct gtaatattta cattttttac catatgtaca tttgtacttt tattttacac      960

ataagggaaa aaataagacc actttgagca gttgcctgga aggctgggca tttccatcat     1020

atagacctct gcccttcaga gtagcctcac cattagtggc agcatcatgt aactgagtgg     1080

actgtgcttg tcaacggatg tgtagctttt cagaaactta attggggatg aatagaaaac     1140

ctgtaagctt tgatgttctg gttacttcta gtaaattcct gtcaaaatca attcagaaat     1200

tctaacttgg agaatttaac attttactct tgtaaatcat agaagatgta tcataacagt     1260

tcagaatttt aaagtacatt ttcgatgctt ttatgggtat ttttgtagtt tctttgtaga     1320

gagataataa aaatcaaaat atttaatgaa aa                                   1352


<210>  282
<211>  3965
<212>  DNA
<213>  homo sapiens

<400>  282
atctgacgag cggccattca tcaggccggc tggcctatca atgacattgc tcccatcggg       60

gctcctataa aatgatgctt tttcccatga aacatccgca aacattttga cgggtttggc      120

tttgcccggc tggattactg agtgtcccct tgctcgctcg ctttttctct ctcccccttc      180

tccgagctcg ctcccttctc tccctctctc tcctcttttc ttctttctct tttctttcct      240

cttctttttc ttttcttttc ctttcctcct ttatccttgt gccccctcac tttctgcgtc      300

tctctctctc cccttctccc tccctccctc ccttcctccc tgggcatctc tagcacaggg      360

gatccccaaa catcaggact tttggggggc gcctgtgctg tccatgggaa gagcatgcat      420

tgtgggttac tggaggaacc cgacatggat tccacagaga gctggattga aagatgtctc      480

aacgaaagtg aaaacaaacg ttattccagc cacacatctc tggggaatgt ttctaatgat      540

gaaaatgagg aaaaagaaaa taatagagca tccaagcccc actccactcc tgctactctg      600

caatggctgg aggagaacta tgagattgca gagggggtct gcatccctcg cagtgccctc      660

tatatgcatt acctggattt ctgcgagaag aatgataccc aacctgtcaa tgctgccagc      720

tttggaaaga tcataaggca gcagtttcct cagttaacca ccagaagact cgggacccga      780

ggacagtcaa agtaccatta ctatggcatt gcagtgaaag aaagctccca atattatgat      840

gtgatgtatt ccaagaaagg agctgcctgg gtgagtgaga cgggcaagaa agaagtgagc      900

aaacagacag tggcatattc accccggtcc aaactcggaa cactgctgcc agaatttccc      960

aatgtcaaag atctaaatct gccagccagc ctgcctgagg agaaggtttc tacctttatt     1020

atgatgtaca gaacacactg tcagagaata ctggacactg taataagagc caactttgat     1080

gaggttcaaa gtttccttct gcacttttgg caaggaatgc cgccccacat gctgcctgtg     1140

ctgggctcct ccacggtggt gaacattgtc ggcgtgtgtg actccatcct ctacaaagct     1200

atctccgggg tgctgatgcc cactgtgctg caggcattac ctgacagctt aactcaggtg     1260

attcgaaagt ttgccaagca actggatgag tggctaaaag tggctctcca cgacctccca     1320

gaaaacttgc gaaacatcaa gttcgaattg tcgagaaggt tctcccaaat tctgagacgg     1380

caaacatcac taaatcatct ctgccaggca tctcgaacag tgatccacag tgcagacatc     1440

acgttccaaa tgctggaaga ctggaggaac gtggacctga acagcatcac caagcaaacc     1500

ctttacacca tggaagactc tcgcgatgag caccggaaac tcatcaccca attatatcag     1560

gagtttgacc atctcttgga ggagcagtct cccatcgagt cctacattga gtggctggat     1620

accatggttg accgctgtgt tgtgaaggtg gctgccaaga gacaagggtc cttgaagaaa     1680

gtggcccagc agttcctctt gatgtggtcc tgtttcggca caagggtgat ccgggacatg     1740

accttgcaca gcgcccccag cttcgggtct tttcacctaa ttcacttaat gtttgatgac     1800

tacgtgctct acctgttaga atctctgcac tgtcaggagc gggccaatga gctcatgcga     1860

gccatgaagg gagaaggaag cactgcagaa gtccgagaag agatcatctt gacagaggct     1920

gccgcaccaa ccccttcacc agtgccatcg ttttctccag caaaatctgc cacatctgtg     1980

gaagtgccac ctccctcttc ccctgttagc aatccttccc ctgagtacac tggcctcagc     2040

actacaggag caatgcagtc ttacacgtgg tctctaacat acacagtgac gacggctgct     2100

gggtccccag ctgagaactc ccaacagctg ccctgtatga ggaacactca tgtgccttct     2160

tcctccgtca cacacaggat accagtttat ccccacagag aggaacatgg atacacggga     2220

agctataact atgggagcta tggcaaccag catcctcacc ccatgcagag ccagtatccg     2280

gccctccctc atgacacagc tatctctggg ccactccact atgcccctta ccacaggagc     2340

tctgcacagt acccttttaa tagccccact tcccggatgg aaccttgttt gatgagcagt     2400

actcccagac tgcatcctac cccagtcact ccccgctggc cagaggtgcc ctcagccaac     2460

acgtgctaca caagcccgtc tgtgcattct gcgaggtacg gaaactctag tgacatgtat     2520

acacctctga caacgcgcag gaattctgaa tatgagcaca tgcaacactt tcctggcttt     2580

gcttacatca acggagaggc ctctacagga tgggctaaat gactgctatc ataggcatcc     2640

atatttaata ttaataataa taattaataa taataataaa cccaacaccc atcccccaga     2700

agactttatc tctatacatt gtaactcatg ggctattcct aagtgcccat tttcctaatg     2760

aacatgagga tgggatcaat gtgggatgaa taaactttag ttcagaaaca ggacttacta     2820

aaagtcagtg ggactgggtt tctgtagcca agccagactt gactgtttct gtagagcact     2880

atctcgggca ggccattctg tgccttttcc ctctgttcca tgactttgct ttgtgttggc     2940

aaccacttct agtaagctac tgattttcct gttgacaaaa tctctttagt cttgaaggat     3000

ggatactgga gacagaatct ggtttgtgtt cttggatggg cacataattt accaagagca     3060

ttcaccttgc catctgtctt gtcattgtac tgtacaagga acagccctca gacgtgttct     3120

gcacatccct tcttcctggt ggtaccatcc ctatttcctg gagcaccagg gctaaatggg     3180

gagctatctg gaaactctag attttctgtc atacccacat ctgtcacagt acctgcattg     3240

tcttggaatg taagcactgt cttgagggaa ggaagaggtc tgttctgtat tgccttaagt     3300

tgattgaggt ttgtaggaga ctggttcttc tacatacaag gatttgtctt aagtttgcac     3360

aatggctagt gtcagcaaaa ggcaggagag ggtttttgtt ttttttttaa gttctatgag     3420

aatgtggatt tatggcattg agtatcacac tcagctctgc tgtgttaact ttgtgaaact     3480

ggatggaaca aactttaact taccaagcac caagtgtgaa agtgactttc acggttcctt     3540

cataaaacta taataatatc cgacactttg atagaaaaaa attcaaagct gtgcctttga     3600

gcctatacta tactgtgtat gtgtggaaat aaaaatgtat tgtacttttg gagaattttt     3660

tgtaggcatt tttctgtcag atttgtagta atttgtgagg tttgttagag attaatatag     3720

gttttctttc tgtattataa aatgcaccaa gcaattatgg tggacctatt accctatggg     3780

taagaaataa atggaaatat gacatcggat gtttcagcaa ctgttctgta aataaaatct     3840

ttgatcacac cactcagtgt gataattgtg tctacagcta aaatggaaat agttttatct     3900

gtacagttgt gcaagatatg aatggtttca cactcaaata aaaaatattg aaacgacaaa     3960

aaaaa                                                                 3965


<210>  283
<211>  7384
<212>  DNA
<213>  homo sapiens

<400>  283
gattcgggcc ggctcgcggg cgctgccagt ctcgggcggc ggtgtccggc gcgcgggcgg       60

cctgctgggc gggctgaagg gttagcggag cacgggcaag gcggagagtg acggagtcgg      120

cgagcccccg cggcgacagg ttctctactt aaaagacaat gactactgat gaaggtgcca      180

agaacaatga agaaagcccc acagccactg ttgctgagca gggagaggat attacctcca      240

aaaaagacag gggagtatta aagattgtca aaagagtggg gaatggtgag gaaacgccga      300

tgattggaga caaagtttat gtccattaca aaggaaaatt gtcaaatgga aagaagtttg      360

attccagtca tgatagaaat gaaccatttg tctttagtct tggcaaaggc caagtcatca      420

aggcatggga cattggggtg gctaccatga agaaaggaga gatatgccat ttactgtgca      480

aaccagaata tgcatatggc tcggctggca gtctccctaa aattccctcg aatgcaactc      540

tcttttttga gattgagctc cttgatttca aaggagagga tttatttgaa gatggaggca      600

ttatccggag aaccaaacgg aaaggagagg gatattcaaa tccaaacgaa ggagcaacag      660

tagaaatcca cctggaaggc cgctgtggtg gaaggatgtt tgactgcaga gatgtggcat      720

tcactgtggg cgaaggagaa gaccacgaca ttccaattgg aattgacaaa gctctggaga      780

aaatgcagcg ggaagaacaa tgtattttat atcttggacc aaggccaaag aatcctggga      840

gatggatacc aaagaaaaat tggagcaggc tgccattgtc aaagagaagg gaaccgtata      900

cttcaaggtg tgtgagtccc tatgcaatcc tttccatctc aaagaattta ttcaagtgtt      960

ggtgaattgt gctgatattc cctactctga attttgtcaa cactgcttgg taagaataag     1020

ctgcaatttt tataaatctg tcattttcaa tatgaaaaat ggtgagaaaa caatcatgtg     1080

gaaaaaaaaa aaagtacaga ttcctctttt acacattctg ctctagattg taaccttcca     1140

tacaggcaga ccaggtctgg catccccacc caccacagta tcactcactc ctaaagcatc     1200

ttgcttggta catagttggc actcaacaag tgtttttgga atgaaaaaag aatgaataga     1260

ataattgtta gcaaagaatg gaattcataa gggtaagttt cacatcattt ttctttcttc     1320

cttttttttt ttttgtatga gagacagggt ctccctttct ttcccaggct ggtctcaaac     1380

ttctagcctc aagcaatcct cccacctcag cttcccaaag tgctgagatt acaggcgtga     1440

gccactgcac cgggcccatc ttcctttaga ctgtcttgat gaagtcacta gagcatatga     1500

taaaaggaga gaggacatgc acaaatttca aaacaaactg acaggagagt attgattgct     1560

tctaatggcc aagatgattc ctgcacactt gcttttatga ggaatctccg gatattcctg     1620

aatgatattc atcataaatt gcttctcaga aacccttctt ggagcaacta ggagtgtgat     1680

attttctcac ttagatctta aacctctaga tgtaagaaaa aaagaaaccg cccttcattc     1740

tgttttaatc agtgttctac ccattgcttc cccaccccaa atatatgcct tctccatgtc     1800

aagcagaaag ggcttagtga tgagaattag agggagaatg ggagttctgt caaggtttct     1860

ttcgttttct gccactgcaa tacagaaatt agatgttttt cagcagtata aagcagtgag     1920

gcataagtgt actttaacaa gtctttatgg ggcatctgct ataagacatg ctattattaa     1980

gttacaacct tgtcaggagg gaggagtggc aatgttaatc caaatgaaac aactagagaa     2040

ttatgtaaga atatataatc aacccaaaat taacacagcc agagggcacc atgtgttttc     2100

agaatttgag ctgagacaat attgggtcat gaaatcagtt ttgtggaagt gtattgcaat     2160

atgttataag gatcagtttt gttgcataaa actttgcttg tgtatgagta agtactggat     2220

tgcatatttc ttactgtggg tggtattcaa acaaatttta aatcatgggt ttagataagt     2280

ataaatatat aaatatgtta tttatcatta tttactatgt atactaaact cttatggatc     2340

accagaaagc atgggggtat gatagaataa gctcagaatt gggaaaaatg ggctttattg     2400

ctcttcaaat gatttagtca tttaaggtcc aaagaggtta tattttcaag tgaaaaatag     2460

gggagttaga tgttccccaa gtttctttcc agcctgaatt tctgtgagtt tctaaactct     2520

caagaacaag tgttattttt ttggttttgt tttgttttta attctaattg aggtatattg     2580

gatacttcta aactattcaa gtaagattcc aagtgggtta tttgtatatc caaatacata     2640

atacactaga gggaaaaatg tttctacaaa atttcttaag atcgtgagtc cttaacagta     2700

ttttctatat ttccgaagtc cataaaaatc cttaactata ttttatatat ttcctcaata     2760

cttccaaata gaatattaac agtttgggaa gatttgaggc ttttggcctt tgactagaat     2820

tatatcgatt cagtgtagta aaacagctca gctattcaga ggctctaatc ggtgctatga     2880

tacagaattt tggagaacat tattggtaat gaaataatgt tatgaagcca tctgtcatat     2940

agctgtgttc tgaatatata cagagagatg gccagaatta gtgatcagta gcagaaagca     3000

atgagtgtct gtacagttac ttaactttgt tgcttatcag catcacaact gcaagagtga     3060

tactattatg aacctactta aaattaccaa tctttggata aaatctggat cagcagtcac     3120

acacatggaa aaaattattt ttaacatgga atttgatagg caaaattttt caaaacatta     3180

gtccattggg gaaaaattaa tgaaaggttc aaaaccactg acctgagact tttctcccag     3240

aatgtctctg aacattttgt accactaaaa acttccctgg aggcaccttt ataattatag     3300

gtaaaagatc ccagcagtag tcctagcgtt agctgtaaaa cttcaaaatg gttagtagat     3360

agtttcctgt acatattccc ttcccaactc agggcaggtt tcaatctgcc atactgccct     3420

cccgggcctt gtctttccag ggtgtctgac ttggcatgtt atgcatttgc acagagtcca     3480

gatgtgtagg tgagagcaga gatgggctga actaaagatc tgtatttcat gccatctgca     3540

tattggaatt ctgtttccat tgatctgttg gtttggttta tacctaaatg ggtaaagcct     3600

ctctcctgag taggattgaa ttgtactcag cttttaagtg ggaatgattt tgccattgaa     3660

gatgtaaagt cctcatttca acctctgaat actaaagaga agaaaaatag agaactctat     3720

ttggctctga aaataattat taagtacagg taacagcata atattaagcc aggcattgtg     3780

caagcgagtt aaacagacac gatttttgcc ctcatagctg acagtgttct gcaggacagg     3840

agcattaact cacacctggt cagtgttttt cttttttctg acttggcagc agagtggcaa     3900

gaaggctaag aacactgaag tgatgtggga ttcttgcgcc cccttgtgct tctcctggga     3960

agaaagcatt tctaaaacaa actagttgag gagaattgtt caacctctaa actcttcaga     4020

taaatcgggc tttgctatat tttcaccacc cttgctgttc caagatacca gtaatgtgat     4080

ttagaaacaa gccgtttatg actctaggat ttgatgtttt aaaaaaaatt cctaagaaga     4140

gtccaccctg tctttcatct ctttccttta gtgcagaatt tttcaacctc agtactatca     4200

acatttggag tgggataatt cttgattgtg tggggctgtc ttgtgcattg tagaatattt     4260

agcagcattc ctggcctctg cccattagat gccagtagca tcctacccag ttatgacaac     4320

taaaaatgcc tccagacctg ccaggtgttc cctggggggc aaaatcaccc cccagttgag     4380

aactgcttta gtacctcaga agcagggagt acaagacaga cttttcgcta attggaagtt     4440

gaagtctaaa taaagttaca tgatatatat gcaagagctt tcaaaaaatt aaaatgccct     4500

atgtgaagga actattaaga agtctaatac ctgttttttg tgttttgttt tgttttacca     4560

tggccttcta ccattctgat tattcagaac ttattgaaat gttaagatct aggtttttgt     4620

cctccctggc tcttcttttc tttccctata caatatatta ggagataatc agaaaagtta     4680

agttaatcaa tgcattagag agggaggagg agagaggatg aagaaatgag gcatgacagg     4740

ggaaatgcct gtccttccta tctcatctca gtgaaacaac acttttcatt tccacccaca     4800

cattttttgc tcccaatgat agcaaaaggt tttgttgttg gtattgtttt tagagagaga     4860

gggtcttact ctgtcaccca ggctggagtg cagtggcaca agcatagcta actgcagctt     4920

cgaactcctg gacttaagag atcctcctgc ctcagcttcc caaagtgctg ggactatagg     4980

cgtgagccac cacaccactt tagaaaaagt cttgattcca tatttacatt cctttgattt     5040

caatatttac tcaacaaacc tttattaaag acctcttggt gctaaaccct gaatattcca     5100

aaagggagag gacaatgctg cctgtcctca aagaccagca agagaaaagg cagtgacaga     5160

aagaaaatgc cgacctgaaa ctggtgagga ctttattctt ttttttttgt agcatccaaa     5220

aaaggagtgg taggcctaag actatgacaa aatttaagta ttgtcttagc ttgggctgcc     5280

acagtaaaat accatacact gggtggcttc aacaacagga atttacttct ggagactgta     5340

agtcccagat caaggtgtta gcaggatcag tgtctgggga gggcctctcc tctggttcct     5400

tgtagctccc ttcttgctgt gttctcacat ggcctttcca catgcatgtg agtggagaga     5460

gggcagaggg cagcaagcac ccgagtttct tcttataaag gctctaatcc catcatgagg     5520

ccccaccctc atgaccacat ctaacctaat tccctcccca aatgctccat ctgcaaatat     5580

cacattcggg gtgagggctt caacatagga atttaggatg ggggacacaa ttcagtccat     5640

agcaaatcta atttcctcaa gaatttcagc atttaaaata aaatgccctg gtttcgtgtt     5700

cttatgaatg acctgtatca cacacttctg aggcagagag ggtgacagac tttgatttta     5760

gtgccagtct tccctctcct aagtgagtga cttgggaaga aggatgttcg agggatgtag     5820

cctggccctc attcacaccc aggccctcca gctggaacag gtctgcccca tcttcatcac     5880

cagaaaatcc acaccagggc ttcctttcta caggcagagc tcgtttctta catcacccac     5940

ttgaagtcct gtatcacagg catgtcctct tagacctgct ctatggtttt tctcttactc     6000

agactccttg ggtgagggtt ggagtatttg tggggagaga caactcggca gtgagatgta     6060

cgcgctgctt gggctgtggt aaatcctagt aacatggtct taacactgtt ggtcaggcat     6120

tgaatttaat gtcctaatag gtctggctgc tcctctgcca tctggcagga tgtatcatct     6180

gtggttttga gcttatcacc tcctcaaagg agaatcccca cttgtactcc tgtttctatt     6240

tgcgtattta ccagcgattc cccagtgctt tcatttacct taaaatcaca gtggacacat     6300

tgtctcagcc ctggaggggt tttgttttgt tttgttttgt tttgttttgt ttttgaggag     6360

tctcgctctg tcacccaggc tggagtgcag tggcatgatc ttggctcact gcaacctctg     6420

cctcttaggt tcaagcagtt ctcctgcctc agcctcctaa gtagccggga ttacaggcat     6480

atgccaccat gcctggctca tttttgtatt tttagtagag acggccaggc tggtctcgaa     6540

ctcctgacct caggtgatcc acctgtctcg gcctccaaag tgctgggatt acaggtatga     6600

gccactgtgc tcagccccca gcgtttctca tatgagcatg tatatatata tatattatat     6660

atatattata tatgtttata tttatatata ttatatataa ctgacagacc tttctgatgt     6720

atattgtttt atagttgtta tttatgttgt atgctactat ccaactattc atattcccat     6780

tgcctataga tcaggggtca gcaaactaca gtttgctggc caaatctggt ccctgcctgt     6840

ttttgtaagt acagtttaac tgaaacacag ctgcacccat tgatttacat actgtctaga     6900

gcagcttttg cactacaaat gataagaatt tagtagttgc aacagagact ggttcaaata     6960

ggattggctg tgtttggaac tagcacttgc cagaatgtaa tatttgctgt gaagtgctga     7020

aaagaaaagt aacttccttt tcattttttt agtggcatag tctaaaactg ctcacaatcc     7080

ttttgaaaga ctaaagaata ggccaggtgt ggtggctcat gcctgtaatc ccagcacttt     7140

gggaggccaa ggcaggcgga tcacaaggtc aggagttcaa gaccagcctg gccaacatag     7200

tgaaacgctg tctctactaa aaatacaaaa aaaaatagct gggcttggtg gcggccacct     7260

gtagtcccca gctactcggg aggctgaggc aggagaatcg ctggaacccg ggaggcggag     7320

gttgcagtga gctgagatgg cgccattgca ctccagccct ggagacagtg cgagactgtg     7380

tctc                                                                  7384


<210>  284
<211>  6614
<212>  DNA
<213>  homo sapiens

<400>  284
aggttatgta agggtttgct ttcaccccat tcaaaaggta cctcttcctc ttctcttgct       60

ccctctcgcc ctcattcttg tgcctatgca gacatttgag tagaggcgaa tcactttcac      120

ttctgctggg gaaattgcaa cacgcttctt taaatggcag agagaaggag aaaacttaga      180

tcttctgata ccaaatcact ggaccttaga aggtcagaaa tctttcaagc cctgcaggac      240

cgtaaaatgc gcatgtgtcc aacggaagca ctggggcatg agtggggaag gaatagaaac      300

agaaagaggt tgatattcac tgatggactc caaagaatca ttaactcctg gtagagaaga      360

aaaccccagc agtgtgcttg ctcaggagag gggagatgtg atggacttct ataaaaccct      420

aagaggagga gctactgtga aggtttctgc gtcttcaccc tcactggctg tcgcttctca      480

atcagactcc aagcagcgaa gacttttggt tgattttcca aaaggctcag taagcaatgc      540

gcagcagcca gatctgtcca aagcagtttc actctcaatg ggactgtata tgggagagac      600

agaaacaaaa gtgatgggaa atgacctggg attcccacag cagggccaaa tcagcctttc      660

ctcgggggaa acagacttaa agcttttgga agaaagcatt gcaaacctca ataggtcgac      720

cagtgttcca gagaacccca agagttcagc atccactgct gtgtctgctg cccccacaga      780

gaaggagttt ccaaaaactc actctgatgt atcttcagaa cagcaacatt tgaagggcca      840

gactggcacc aacggtggca atgtgaaatt gtataccaca gaccaaagca cctttgacat      900

tttgcaggat ttggagtttt cttctgggtc cccaggtaaa gagacgaatg agagtccttg      960

gagatcagac ctgttgatag atgaaaactg tttgctttct cctctggcgg gagaagacga     1020

ttcattcctt ttggaaggaa actcgaatga ggactgcaag cctctcattt taccggacac     1080

taaacccaaa attaaggata atggagatct ggttttgtca agccccagta atgtaacact     1140

gccccaagtg aaaacagaaa aagaagattt catcgaactc tgcacccctg gggtaattaa     1200

gcaagagaaa ctgggcacag tttactgtca ggcaagcttt cctggagcaa atataattgg     1260

taataaaatg tctgccattt ctgttcatgg tgtgagtacc tctggaggac agatgtacca     1320

ctatgacatg aatacagcat ccctttctca acagcaggat cagaagccta tttttaatgt     1380

cattccacca attcccgttg gttccgaaaa ttggaatagg tgccaaggat ctggagatga     1440

caacttgact tctctgggga ctctgaactt ccctggtcga acagtttttt ctaatggcta     1500

ttcaagcccc agcatgagac cagatgtaag ctctcctcca tccagctcct caacagcaac     1560

aacaggacca cctcccaaac tctgcctggt gtgctctgat gaagcttcag gatgtcatta     1620

tggagtctta acttgtggaa gctgtaaagt tttcttcaaa agagcagtgg aaggacagca     1680

caattaccta tgtgctggaa ggaatgattg catcatcgat aaaattcgaa gaaaaaactg     1740

cccagcatgc cgctatcgaa aatgtcttca ggctggaatg aacctggaag ctcgaaaaac     1800

aaagaaaaaa ataaaaggaa ttcagcaggc cactacagga gtctcacaag aaacctctga     1860

aaatcctggt aacaaaacaa tagttcctgc aacgttacca caactcaccc ctaccctggt     1920

gtcactgttg gaggttattg aacctgaagt gttatatgca ggatatgata gctctgttcc     1980

agactcaact tggaggatca tgactacgct caacatgtta ggagggcggc aagtgattgc     2040

agcagtgaaa tgggcaaagg caataccagg tttcaggaac ttacacctgg atgaccaaat     2100

gaccctactg cagtactcct ggatgtttct tatggcattt gctctggggt ggagatcata     2160

tagacaatca agtgcaaacc tgctgtgttt tgctcctgat ctgattatta atgagcagag     2220

aatgactcta ccctgcatgt acgaccaatg taaacacatg ctgtatgttt cctctgagtt     2280

acacaggctt caggtatctt atgaagagta tctctgtatg aaaaccttac tgcttctctc     2340

ttcagttcct aaggacggtc tgaagagcca agagctattt gatgaaatta gaatgaccta     2400

catcaaagag ctaggaaaag ccattgtcaa gagggaagga aactccagcc agaactggca     2460

gcggttttat caactgacaa aactcttgga ttctatgcat gaagtggttg aaaatctcct     2520

taactattgc ttccaaacat ttttggataa gaccatgagt attgaattcc ccgagatgtt     2580

agctgaaatc atcaccaatc agataccaaa atattcaaat ggaaatatca aaaaacttct     2640

gtttcatcaa aagtgactgc cttaataaga atggttgcct taaagaaagt cgaattaata     2700

gcttttattg tataaactat cagtttgtcc tgtagaggtt ttgttgtttt attttttatt     2760

gttttcatct gttgttttgt tttaaatacg cactacatgt ggtttataga gggccaagac     2820

ttggcaacag aagcagttga gtcgtcatca cttttcagtg atgggagagt agatggtgaa     2880

atttattagt taatatatcc cagaaattag aaaccttaat atgtggacgt aatctccaca     2940

gtcaaagaag gatggcacct aaaccaccag tgcccaaagt ctgtgtgatg aactttctct     3000

tcatactttt tttcacagtt ggctggatga aattttctag actttctgtt ggtgtatccc     3060

ccccctgtat agttaggata gcatttttga tttatgcatg gaaacctgaa aaaaagttta     3120

caagtgtata tcagaaaagg gaagttgtgc cttttatagc tattactgtc tggttttaac     3180

aatttccttt atatttagtg aactacgctt gctcattttt tcttacataa ttttttattc     3240

aagttattgt acagctgttt aagatgggca gctagttcgt agctttccca aataaactct     3300

aaacattaat caatcatctg tgtgaaaatg ggttggtgct tctaacctga tggcacttag     3360

ctatcagaag accacaaaaa ttgactcaaa tctccagtat tcttgtcaaa aaaaaaaaaa     3420

aaaaagctca tattttgtat atatctgctt cagtggagaa ttatataggt tgtgcaaatt     3480

aacagtccta actggtatag agcacctagt ccagtgacct gctgggtaaa ctgtggatga     3540

tggttgcaaa agactaattt aaaaaataac taccaagagg ccctgtctgt acctaacgcc     3600

ctatttttgc aatggctata tggcaagaaa gctggtaaac tatttgtctt tcaggacctt     3660

ttgaagtagt ttgtataact tcttaaaagt tgtgattcca gataaccagc tgtaacacag     3720

ctgagagact tttaatcaga caaagtaatt cctctcacta aactttaccc aaaaactaaa     3780

tctctaatat ggcaaaaatg gctagacacc cattttcaca ttcccatctg tcaccaattg     3840

gttaatcttt cctgatggta caggaaagct cagctactga tttttgtgat ttagaactgt     3900

atgtcagaca tccatgtttg taaaactaca catccctaat gtgtgccata gagtttaaca     3960

caagtcctgt gaatttcttc actgttgaaa attattttaa acaaaataga agctgtagta     4020

gccctttctg tgtgcacctt accaactttc tgtaaactca aaacttaaca tatttactaa     4080

gccacaagaa atttgatttc tattcaaggt ggccaaatta tttgtgtaat agaaaactga     4140

aaatctaata ttaaaaatat ggaacttcta atatattttt atatttagtt atagtttcag     4200

atatatatca tattggtatt cactaatctg ggaagggaag ggctactgca gctttacatg     4260

caatttatta aaatgattgt aaaatagctt gtatagtgta aaataagaat gatttttaga     4320

tgagattgtt ttatcatgac atgttatata ttttttgtag gggtcaaaga aatgctgatg     4380

gataacctat atgatttata gtttgtacat gcattcatac aggcagcgat ggtctcagaa     4440

accaaacagt ttgctctagg ggaagaggga gatggagact ggtcctgtgt gcagtgaagg     4500

ttgctgaggc tctgacccag tgagattaca gaggaagtta tcctctgcct cccattctga     4560

ccacccttct cattccaaca gtgagtctgt cagcgcaggt ttagtttact caatctcccc     4620

ttgcactaaa gtatgtaaag tatgtaaaca ggagacagga aggtggtgct tacatcctta     4680

aaggcaccat ctaatagcgg gttactttca catacagccc tcccccagca gttgaatgac     4740

aacagaagct tcagaagttt ggcaatagtt tgcatagagg taccagcaat atgtaaatag     4800

tgcagaatct cataggttgc caataataca ctaattcctt tctatcctac aacaagagtt     4860

tatttccaaa taaaatgagg acatgttttt gttttctttg aatgcttttt gaatgttatt     4920

tgttattttc agtattttgg agaaattatt taataaaaaa acaatcattt gctttttgaa     4980

tgctctctaa aagggaatgt aatattttaa gatggtgtgt aacccggctg gataaatttt     5040

tggtgcctaa gaaaactgct tgaatattct tatcaatgac agtgttaagt ttcaaaaaga     5100

gcttctaaaa cgtagattat cattccttta tagaatgtta tgtggttaaa accagaaagc     5160

acatctcaca cattaatctg attttcatcc caacaatctt ggcgctcaaa aaatagaact     5220

caatgagaaa aagaagatta tgtgcacttc gttgtcaata ataagtcaac tgatgctcat     5280

cgacaactat aggaggcttt tcattaaatg ggaaaagaag ctgtgccctt ttaggatacg     5340

tgggggaaaa gaaagtcatc ttaattatgt ttaattgtgg atttaagtgc tatatggtgg     5400

tgctgtttga aagcagattt atttcctatg tatgtgttat ctggccatcc caacccaaac     5460

tgttgaagtt tgtagtaact tcagtgagag ttggttactc acaacaaatc ctgaaaagta     5520

tttttagtgt ttgtaggtat tctgtgggat actatacaag cagaactgag gcacttagga     5580

cataacactt ttggggtata tatatccaaa tgcctaaaac tatgggagga aaccttggcc     5640

accccaaaag gaaaactaac atgatttgtg tctatgaagt gctggataat tagcatggga     5700

tgagctctgg gcatgccatg aaggaaagcc acgctccctt cagaattcag aggcagggag     5760

caattccagt ttcacctaag tctcataatt ttagttccct tttaaaaacc ctgaaaacta     5820

catcaccatg gaatgaaaaa tattgttata caatacattg atctgtcaaa cttccagaac     5880

catggtagcc ttcagtgaga tttccatctt ggctggtcac tccctgactg tagctgtagg     5940

tgaatgtgtt tttgtgtgtg tgtgtctggt tttagtgtca gaagggaaat aaaagtgtaa     6000

ggaggacact ttaaaccctt tgggtggagt ttcgtaattt cccagactat tttcaagcaa     6060

cctggtccac ccaggattag tgaccaggtt ttcaggaaag gatttgcttc tctctagaaa     6120

atgtctgaaa ggattttatt ttctgatgaa aggctgtatg aaaataccct cctcaaataa     6180

cttgcttaac tacatataga ttcaagtgtg tcaatattct attttgtata ttaaatgcta     6240

tataatgggg acaaatctat attatactgt gtatggcatt attaagaagc tttttcatta     6300

ttttttatca cagtaatttt aaaatgtgta aaaattaaaa ccagtgactc ctgtttaaaa     6360

ataaaagttg tagtttttta ttcatgctga ataataatct gtagttaaaa aaaaagtgtc     6420

tttttaccta cgcagtgaaa tgtcagactg taaaaccttg tgtggaaatg tttaactttt     6480

attttttcat ttaaatttgc tgttctggta ttaccaaacc acacatttgt accgaattgg     6540

cagtaaatgt tagccattta cagcaatgcc aaatatggag aaacatcata ataaaaaaat     6600

ctgctttttc atta                                                       6614


<210>  285
<211>  4746
<212>  DNA
<213>  homo sapiens

<400>  285
agcacaaccg cctaagcggc ggaactctgg agagtgcgga acctaggatc ctaggaaact       60

gaaggcaacg gaacctgggg gcgatggaat ccgggagcgg tggaacccgg agcctgtaga      120

acttgaatct agaggaacct gacagcggcg ccgagggggc cacccggact ctgtttggaa      180

cggaagcaca gtgtccgccg cttcctggtt gcgggtcagc gcccaggtcc tgggctggcc      240

gccgggatgt tgccctacac agtgaacttc aaggtgtcgg cgcgcaccct cacgggggcc      300

ctcaacgccc acaacaaggc ggcggtggac tggggctggc aaggtttaat tgcttatgga      360

tgtcattcac ttgtggtagt gattgattcc attactgccc aaactcttca agttttagaa      420

aagcataaag ctgatgttgt aaaggttaaa tgggccaggg aaaactatca ccataacatt      480

ggctcaccat attgcttacg gttagcttct gctgatgtca atgggaagat catcgtctgg      540

gatgtagcag caggagtagc tcagtgtgag atccaagagc atgccaagcc tatccaggat      600

gttcagtggt tgtggaatca agatgcttcc cgcgatttac tgcttgctat ccacccgcca      660

aattacattg tgctctggaa tgccgacact ggcaccaaac tatggaagaa gagctatgca      720

gataacattc tttctttttc ttttgaccct tttgatccct cacatttaac tttgcttacc      780

agcgagggta ttgttttcat ctcagacttc tccccatcca agcctccctc aggccctggg      840

aaaaaagttt acatatccag cccacactct agcccagctc ataacaagct ggccacagcc      900

acaggtgcca agaaagctct aaataaagta aaaattttaa tcactcaaga gaaacctagt      960

gctgaattca taactctcaa tgattgcctt cagttggcat acctgccttc aaaaaggaat     1020

cacatgttgt tgctctatcc tcgagagatt ttaatccttg accttgaggt gaatcagacg     1080

gtgggtgtga ttgcaataga acgcacagga gttccatttt tacaggtaat accctgcttt     1140

cagcgtgatg gtttattttg tctacatgaa aatggttgta taactttacg tgttcgaaga     1200

tcttataata acatttttac cacttcaaat gaggaaccag atccagatcc agttcaggag     1260

cttacctatg atttacgaag ccagtgtgat gcaatcaggg tgacaaaaac cgtccgtccc     1320

ttcagtatgg tgtgctgtcc tgtcaatgag aatgcagccg ccctcgtagt gagtgatggc     1380

agggtcatga tatgggaact caagtctgca gtttgtaatc gaaattcacg gaacagtagt     1440

tctggtgtgt cacctttata ttcaccagtg tctttctgtg gaattcctgt aggagtgcta     1500

cagaataaac tcccagacct ttccttagat aacatgattg ggcaaagtgc aattgctggg     1560

gaagaacatc ccagaggttc aattctgcgg gaagtgcacc tcaagttcct gctgacggga     1620

ctgctttcag gactgcccgc accacagttt gctattcgta tgtgtccacc gttgaccaca     1680

aaaaacatca agatgtatca gccactgctg gctgttggta caagtaatgg ttctgtcctg     1740

gtgtaccatc tcaccagtgg tctgctacac aaagagttaa gcatccactc atgtgaagtc     1800

aagggtattg aatggacaag tttgactagt tttctttctt ttgctacctc aacaccaaac     1860

aatatgggat tagtgagaaa tgaacttcaa ctggttgatc ttccaacagg taggagcatt     1920

gcttttcgtg gtgaaagagg caatgatgaa tctgccatcg aaatgattaa agtatctcat     1980

ttgaagcagt atttggcagt cgtattcaga gataaacccc tggagctatg ggatgttagg     2040

acttgtaccc ttcttagaga gatgtccaaa aacttcccta caataactgc tttggagtgg     2100

tcaccatctc acaacttgaa gagcctgaga aagaagcaac ttgcaactcg agaggccatg     2160

gcccgccaga ccgtagtctc agacacagag ctgagtattg ttgaatcatc tgtgatcagc     2220

ttgctgcagg aggcagaaag taaatctgaa cttagtcaga acatctctgc ccgggaacat     2280

tttgtattta ccgatattga tggccaagtg tatcatctca ctgttgaagg aaactcagta     2340

aaagacagtg ctcggattcc accagatgga agtatgggta gtattacctg catcgcttgg     2400

aaaggtgata cattagtgct tggagatatg gatggaaatt taaatttctg ggacttgaaa     2460

ggcagagtat ccagaggaat acccacacac cgaagttggg tgaggaagat tcgttttgct     2520

cctggtaaag gaaatcaaaa attaatagca atgtacaatg atggagctga agtgtgggat     2580

actaaagagg ttcagatggt gagcagttta agaagtggca gaaatgtgac ctttcgtata     2640

ttggatgtgg actggtgtac gtcagataaa gtgatcttgg cctcagatga tgggtgcatc     2700

agagtcctag agatgtctat gaagtctgcg tgctttagaa tggatgaaca agagttaacc     2760

gagcctgtgt ggtgccccta tctccttgtt ccaagggcct ctcttgcctt gaaagccttc     2820

ttattacacc agccttggaa tggacagtat tctttggaca tttctcatgt tgactatcca     2880

gaaaatgaag aaataaagaa tctcctccaa gaacagttga attcattgtc taatgacata     2940

aagaaactgt tgcttgatcc agaattcact ctcttgcaga ggtgcctgct tgtttcaagg     3000

ctctatggtg atgaatcgga gctgcacttc tggactgtcg ctgcccacta cctgcacagc     3060

ttatcccagg aaaagtcagc cagcacaaca gctcctaaag aagctgctcc tcgagacaaa     3120

ctgagcaacc cactggatat atgctatgac gtgctctgtg aaaatgccta ctttcagaaa     3180

tttcagctag aaagggttaa tctgcaggaa gtgaaacggt caacttatga tcatacaagg     3240

aaatgtacag accagctact gctcttgggt caaacagaca gagctgtgca gttgctgttg     3300

gaaacaagtg cagataacca gcattattac tgtgattcac tgaaagcctg tttagtcact     3360

actgtcacct cgtcaggccc ctctcagagc accattaagt tggtggcaac gaatatgatt     3420

gccaatggca aattggcaga gggcgttcag ttgctctgcc tgatagataa ggctgcagac     3480

gcctgccgct acctgcagac atacggcgag tggaatcggg ctgcatggct ggcaaaagtc     3540

cgtttgaatc ctgaggagtg tgccgatgtt ttaaggcggt gggttgacca cctttgttct     3600

ccacaagtca atcagaaatc aaaggctctc ctggttctcc tctctctggg ctgctttttt     3660

agcgtggcag agacgcttca cagcatgaga tactttgata gagcagcctt atttgtggaa     3720

gcttgcctca agtatggagc atttgaagtc actgaggaca cagagaaact catcactgct     3780

atatatgcag attatgcccg gagtttgaag aacctcggtt ttaagcaggg agcagttctc     3840

tttgcttcaa aagccggagc agctggcaaa gacttattga atgagcttga gtcccccaag     3900

gaagaaccca ttgaagagtg acagcttaat aaatgccagg gaatctgacc tggaaggcag     3960

atgggagggg gctggtctgg ctgtggccac cgtcacagtc caggatgaag aggagtacag     4020

ggtcctgtga gctgtttgac cactgttcta agactatgtg tgcccaaaag cacataagca     4080

tctatgttga gagtaagttt gtatcctgcg ttggtctcag aaagaacgtg aatgcttaag     4140

attttgaaag tacataatat tttatacttt gggagagagc tttaagagtc cctggaaata     4200

ctttttaatt tttttaactt aaaattcaag agactgaatc acttttctca ttgattaaat     4260

gtaaagatta ttgagaaacc tatagtaaat gaaatttgtg agatgttttc tcaaatatat     4320

gctgtgcctg tacttatata cagtctttca agagagatac aaacaaggca gaaacattta     4380

aactagtatt aaaggtagtt taccaaagca ttttttgttt tcttaccttg aaaacacaga     4440

accgttaatt ccttggttta agcagttgct aagttttgta attttaggct cagaggacca     4500

taggaggttt taagatttat gtttagtccg ataggtgagg tctttgatat tttgaatttt     4560

aactcctttt atgatacatc acagtaacct catttttgaa gtctttcttt gtactttaat     4620

gttctctctg ttctaatagt tgaagtatga gatgtaacta ttataaactg ttgctgaaaa     4680

cataaatgtc tgtaacttac aaacatgata aataaattaa aaattccatc caggaaaaaa     4740

aaaaaa                                                                4746


<210>  286
<211>  5081
<212>  DNA
<213>  homo sapiens

<400>  286
tttcagttgg aaggaggtag ggaaaataag tgctttaatt cctaggattt tggaagtaaa       60

aatggaacac cagacaaaaa tggaattttt aggcaaatgt aaagctttgt acttgggtat      120

ctcaaagtat tatacagtgt aaactatcat gattattaac caactagaag tagttctttt      180

ttttaaattt tatttttaat tttagacatg agggtcttgc tatgttgccc aggctgaagt      240

ggctactgac aggcacgatg tggcactgca gcctggaact cttgggctta agtgatcctt      300

cctgcttctt ctatcttaaa aaaaaaaagt tacgcttgct tgttaaaata tttttaaaat      360

gctgtgttta aactaagaag taaatatcca ccccacctct gacttctaaa aattatctaa      420

agtatgactg gtaagatttt tacctttaat cccacataag tctaaaattt gtgttcattt      480

ccaacaacca aagtgtgtca cttttatacc agaattttgt cctgcttata cgtttagtac      540

agaaatctca tgggagagag catccatgca tttacaaatt gttattgaat tattttattg      600

aatgatgaca cccaaactga gctagaacat aattctggct ctgctagtac atcttctgtg      660

tgatcttgga caagtcactc tactttcctt tcaattttct tttctcacag ggagataatc      720

ataaaaacga ctgtaaagta cagcacttca tagagtgctt tttgtttaaa gagctgacaa      780

taaatacgag tctcaaggtc taggaaagcc tccctcacaa cctgagctgc ttgaggacaa      840

gggattttct tttgaatcag cagtacctta tttgtgtatc tgtgatagag ttcctggtac      900

ataagaaggt ctcaataaat atgtgaattt atgaatatta ggcagattgc aaccttgaca      960

ggccactgcc tcttaaatct cctttctgtg atcttttaat atttaacatc taaaaggccg     1020

ccgctacttg ctttgggata agtatccccg gtatgtactt taaaatgccc aagcctagag     1080

aaatgattct tgtcttaagg gcaccatttc gctctcccac cgtaaagcgc cccaggcttg     1140

ggatctgggt cccaaggcta cagggaagag tttggaacgg gaagctcatc ttccggccct     1200

ctgattggcc ggctcgcact ccactcacgc ggcgcgcagc tctgattggc ctcggcggca     1260

cccctcgtcc cgcgactact ttgtgtgctg gggcggcgcg ctccggtcct cccgctcagc     1320

tggcggtctg ggctgctctg gggcagccct tcggtccact gctctgcatc gcgggcgccg     1380

ggaattttcc gagtccgagc ggcatgtaga gcgcatgaag tacaggacaa taaagcttcc     1440

tacacatatc accaggagga tctctttgaa agattcactg caggactacc agagagaata     1500

atttgtctga agcatcatgt gttgaaacaa cagaagtcta ttcacctgtg cactaactag     1560

aaacagagtt acaatgtttt caattctttg agctccagga ctccagggaa gtgagttgaa     1620

aatctgaaaa tgcggccatg gactggttcc tggcgttgga ttatgctcat tctttttgcc     1680

tgggggacct tgctgtttta tataggtggt cacttggtac gagataatga ccatcctgat     1740

cactctagcc gagaactgtc caagattctg gcaaagcttg aacgcttaaa acaacagaat     1800

gaagacttga ggcgaatggc cgaatctctc cggataccag aaggccctat tgatcagggg     1860

ccagctatag gaagagtacg cgttttagaa gagcagcttg ttaaggccaa agaacagatt     1920

gaaaattaca agaaacagac cagaaatggt ctggggaagg atcatgaaat cctgaggagg     1980

aggattgaaa atggagctaa agagctctgg tttttcctac agagtgaatt gaagaaatta     2040

aagaacttag aaggaaatga actccaaaga catgcagatg aatttctttt ggatttagga     2100

catcatgaaa ggtctataat gacggatcta tactacctca gtcagacaga tggagcaggt     2160

gattggcggg aaaaagaggc caaagatctg acagaactgg ttcagcggag aataacatat     2220

cttcagaatc ccaaggactg cagcaaagcc aaaaagctgg tgtgtaatat caacaaaggc     2280

tgtggctatg gctgtcagct ccatcatgtg gtctactgct tcatgattgc atatggcacc     2340

cagcgaacac tcatcttgga atctcagaat tggcgctatg ctactggtgg atgggagact     2400

gtatttaggc ctgtaagtga gacatgcaca gacagatctg gcatctccac tggacactgg     2460

tcaggtgaag tgaaggacaa aaatgttcaa gtggtcgagc ttcccattgt agacagtctt     2520

catccccgtc ctccatattt acccttggct gtaccagaag acctcgcaga tcgacttgta     2580

cgagtgcatg gtgaccctgc agtgtggtgg gtgtctcagt ttgtcaaata cttgatccgc     2640

ccacagcctt ggctagaaaa agaaatagaa gaagccacca agaagcttgg cttcaaacat     2700

ccagttattg gagtccatgt cagacgcaca gacaaagtgg gaacagaagc tgccttccat     2760

cccattgaag agtacatggt gcatgttgaa gaacattttc agcttcttgc acgcagaatg     2820

caagtggaca aaaaaagagt gtatttggcc acagatgacc cttctttatt aaaggaggca     2880

aaaacaaagt accccaatta tgaatttatt agtgataact ctatttcctg gtcagctgga     2940

ctgcacaatc gatacacaga aaattcactt cgtggagtga tcctggatat acattttctc     3000

tctcaggcag acttcctagt gtgtactttt tcatcccagg tctgtcgagt tgcttatgaa     3060

attatgcaaa cactacatcc tgatgcctct gcaaacttcc attctttaga tgacatctac     3120

tattttgggg gccagaatgc ccacaatcaa attgccattt atgctcacca accccgaact     3180

gcagatgaaa ttcccatgga acctggagat atcattggtg tggctggaaa tcattgggat     3240

ggctattcta aaggtgtcaa caggaaattg ggaaggacgg gcctatatcc ctcctacaaa     3300

gttcgagaga agatagaaac ggtcaagtac cccacatatc ctgaggctga gaaataaagc     3360

tcagatggaa gagataaacg accaaactca gttcgaccaa actcagttca aaccatttca     3420

gccaaactgt agatgaagag ggctctgatc taacaaaata aggttatatg agtagatact     3480

ctcagcacca agagcagctg ggaactgaca taggcttcaa ttggtggaat tcctctttaa     3540

caagggctgc aatgccctca tacccatgca cagtacaata atgtactcac atataacatg     3600

caaacaggtt gttttctact ttgccccttt cagtatgtcc ccataagaca aacactgcca     3660

tattgtgtaa tttaagtgac acagacattt tgtgtgagac ttaaaacatg gtgcctatat     3720

ctgagagacc tgtgtgaact attgagaaga tcggaacagc tccttactct gaggaagttg     3780

attcttattt gatggtggta ttgtgaccac tgaattcact ccagtcaaca gattcagaat     3840

gagaatggac gtttggtttt tttttgtttt tgtttttgtt ttttccttta taaggttgtc     3900

tgtttttttt tttttaaata attgcatcag ttcattgacc tcatcattaa taagtgaaga     3960

atacatcaga aaataaaata ttcactctcc attagaaaat tttgtaaaac aatgccatga     4020

acaaattctt tagtactcaa tgtttctgga cattctcttt gataacaaaa aataaatttt     4080

aaaaaggaat tttgtaaagt ttctagaatt ttatatcatt ggatgatatg ttgatcagcc     4140

ttatgtggaa gaactgtgat aaaaagagga gctttttagt ttttcagctt atttactttg     4200

ttttttttcc tgtttctgat atagtaacta attcttaact cagagacatt ggtccatttt     4260

aatactgaaa accaattttc attggtacac attacaaaat tgctaagaac actgtttggg     4320

agctttcatt ctcatatttt ggacattgtt ttaattgagt gaaataatca taactccttg     4380

ctcccagaga agctatcacc tccatttcta aaaccatttc aggtttgttt ggtagtcttt     4440

cttaatgtat ttattatcgc tttttgtgag tagggtcctg ttttatccag gaaccaattt     4500

ctgccctagc ctatcatgcc ctgcttttga gagtaccagg tatctttggg attgggaagc     4560

tggctgtttc agaagtatat gtctcatagt gtgcagaact tggtgaccaa gtgagaagcg     4620

ggaccaatgg gagactcaca atggactgag tcttgggatt atcttttcca aattcttcca     4680

tgttagaatc acttcagaaa ataagacttt gatgctttgt ctctgagcat catttttctc     4740

ctcataaaaa cacttcctta ttgtatgtag cctgcctcct acagaggcct ggtaggtgtt     4800

actgcattct aaaagaaaaa tgtcatctct gtaggagcga ctatcaggcc tagtgtgaaa     4860

tattagggat cctaggcaga agagctatta gtcctggcct tcatatcttc accaaatgaa     4920

aatactgtat ataaaatttc accaccaaac ttaactaaat tctttttctc aagtcaagcc     4980

tcccaaagaa aaaagaaatt aacttcctac agtgtcagca agcaattttc catttagttt     5040

tggtacaaat aaaagtcatt tgaaacaaaa aaaaaaaaaa a                         5081


<210>  287
<211>  4718
<212>  DNA
<213>  homo sapiens

<400>  287
agttgtaaag caaacagtgt aggtattgga agccgttcac acctcctttc cgagtatctg       60

catgccttgc tggcccagag cacaagaccc ccattgtgct cccccggctc agaatccaag      120

gaaagaaagg aagcgaagcc tctgcattga gttctaggac agctgagaca cttggattgg      180

acttaatctt aaacctctgg agttcaagac cttttaaaaa gggctaaata aacaatctct      240

acatgtaaaa ggccactgac tcctacttcc tctgtataga gcaactgttg aactcagctg      300

cctgtagata gcggtgggtg tgctcgcaaa cgtgccgcca tgtctgttac gctaacatct      360

gtgaagagag tgcaaagttc tccaaaccta ttggctgcag ggcgtgattc tcagtcacca      420

gactcagctt ggagatctta caatgatggc aatcaggaga cactgaacgg agatgctaca      480

tattcctctc ttgcagcaaa aggttttaga agcgttcgac caaacctaca agataaaaga      540

tcaccaactc agagccagat aacagtgaat ggaaactcag gaggtgccgt gagtcccatg      600

agttactatc agaggccgtt ttccccctcg gcatattctc tcccagcctc actcaactcc      660

agcattgtca tgcagcacgg cacatccctc gattccacag acacatatcc ccagcatgcg      720

cagtctctgg atggcaccac cagcagctct atccccctgt accgatcctc agaggaagag      780

aagagagtga cagtcatcaa agccccgcat tacccaggga tcgggcccgt ggatgaatcc      840

ggaatcccca cagcaattag aacgacagtc gaccggccca aggactggta caagacgatg      900

tttaagcaaa ttcacatggt gcacaagccg gatgatgaca cagacatgta taatactcct      960

tatacataca atgcaggtct gtacaaccca ccctacagtg ctcagtcaca ccctgctgca     1020

aagacccaaa cctacagacc tctttccaaa agccactccg acaacagccc caatgccttt     1080

aaggatgcgt cctccccagt gcctccccca catgttccac ctccagtccc gccgcttcga     1140

ccaagagatc ggtcttcaac agaaaagcat gactgggatc ctccagacag aaaagtggac     1200

acaagaaaat ttcggtctga gccaaggagt atttttgaat atgaacctgg caagtcatca     1260

attcttcagc atgaaagacc accccctctc ccaacaactc cgacacctgt tccaagggaa     1320

cctggccgga agcctctttc tagctcccga ctcggagaag tcactggtag cccctcccct     1380

ccgccccgga gtggcgcccc cacaccaagc tcgcgcgccc cggctctgtc tcccacccgg     1440

cctcctaaaa agcctctgga ctatgttcaa gatcattctt ctggtgtttt caatgaggcc     1500

tccttgtatc agtcctctat agacagaagc ctggaaagac ccatgagttc tgcaagcatg     1560

gccagtgact tcaggaagcg gaggaagagc gagcctgcag tgggtccacc acggggcttg     1620

ggagatcaaa gtgcgagcag gactagccca ggccgagtgg acctcccagg atcaagcacc     1680

actcttacaa agtctttcac tagctcttct ccttcttccc catcaagagc aaaagaccgt     1740

gagtccccta gaagttactc atccactttg actgacatgg ggagaagtgc accaagggaa     1800

agaagaggaa ctccagaaaa agagaaattg cctgcaaaag ctgtttatga ttttaaggct     1860

cagacatcta aggagttgtc atttaagaaa ggagatactg tctacatcct caggaaaatt     1920

gatcaaaatt ggtatgaggg agaacaccac gggagagtgg gcatcttccc gatctcatac     1980

gtagagaaac tcacacctcc tgagaaagca cagcctgcaa gaccacctcc gccagcccag     2040

cccggagaaa tcggagaagc tatagccaaa tacaacttca acgcagacac aaatgtggag     2100

ctgtcactga gaaagggaga tagagttatt cttcttaaaa gagttgatca aaactggtat     2160

gaaggtaaaa tcccaggaac caacagacaa ggcatcttcc ctgtttccta tgtggaggtc     2220

gtcaagaaga acacaaaagg tgctgaggac taccctgacc ctccaatacc ccacagctat     2280

tctagtgata ggattcacag cttgagctca aataagccac agcgtcctgt gtttactcat     2340

gaaaatattc aaggtggggg ggaaccgttt caggctctgt ataactatac tcccaggaat     2400

gaagatgagc tggagctcag agaaagtgat gtcattgatg tcatggaaaa gtgtgatgac     2460

ggctggtttg tggggacctc aagaagaacc aaattctttg gtactttccc cggaaactac     2520

gtcaagaggc tgtgaattgc gctccctcct tctgtagagg ccgcctgcca gccatgcacc     2580

tgcgtcaacg cgcctgaaac accccgcggg cctcccgttg tcatgcctta cggtttccaa     2640

tgcgccgtca ccatctccac ctgccaccaa accaccagca gagtagccgc cgctgctgtg     2700

agcctgggga cgacatggca ggctggtccc cctccgtgaa agtgtggatt cctacttcct     2760

gctctaagct ttgacacgtc aaaatgtggg atcagaaaga aaaaaatcat gatatttaaa     2820

aatggtcaaa tatttgaggc aaaaaaaaaa aaaaaaagtg tctccaggag gctgtccagc     2880

ctcgtggctc catttcaaca tctcccccca ggcgatgttc tcccccaaga cgaccagaaa     2940

attgtttatt ggggaatgct gtggtttgca ttttcatatt cttcgcttgg cagtgtgtat     3000

tcttttcaca agtttgccta gtgtcttggt ttacacaata tgacaactgt aactgtactt     3060

tagctattgt ttgcctgcac atacatgttg taatatgcac agtgattaca acctttaaag     3120

caagaggagg cgagttaatt tggatgagtg tgattttgct gattgaatgt gagttttcaa     3180

ataggagtct ttttctgcaa tttgtttgca ttttttagaa gtgcaaacag taagtaaata     3240

aaagccttcg gtaataatca tgacaataca agaggctgag ctaggctaca ggggaaaact     3300

attgtgttgt aaagttgcat cgctatttta tattaaaatg taatgatcag catcatgaac     3360

aatgagctct tagtgtttta tttatctgaa aaaatgtaag taaaagcagt gttagtgaga     3420

ggtgcaaaga attattctaa cagacacctg aaagtatctg taagcaatac tagtaggtaa     3480

gatttcactg tgtgtacaca tacacatttg agattgtatg agaacatata atccatatga     3540

tatgttgtac attttatgga aatgtaatag aatctcacac attattttat agaaatagag     3600

tacagaagca tcacaagtat taaagttggt tttagcaagg attaggatta ctacaattat     3660

ttttactata ataattattt ttcttctatg gaactcagaa tcctggctac atttgaggac     3720

aggaatatgt tgagcctgat tttcctggtg tgtgtaaaat atttcctagg aataaattag     3780

gcacttttta gaagcaatgt taaatcattc aggttttatt ttctgccctg aagcagaaat     3840

ttaaaaaatg atattgggac ctggaaggtt taatatggtt cacagtgcct gaattacacc     3900

tgctccgaaa actagctttg tatttcttat gactttgcat aagaactgtt catctttgga     3960

tcttgagcac cttacagata aaacttttta tggcatctct ttcatggaca gtgatattga     4020

tcttttcaca atgtacgtag cctctagaat tttgtacata tgtttgctct ttttttgtac     4080

agactagttg ttgagaaaac aggggcgttt cctaatttgg tctttatcct gcgacaacac     4140

tttcagcaga ctagcctctc cttatctcac agatcacaag cacccctaga tagtgtgatt     4200

ctgtcagata gcatttatgc aaaaatctat gaagttaaaa gatcgtagaa gccaaatgaa     4260

atgtacatat ctactgactg atgacaaggg aatttcatta ggaagaaggt aaagaaacat     4320

cgttgagtag cctaccttga tttctgtcaa gttcataacc agcttcatat tttaaaggct     4380

tcaggtttga aattaagtca actgcatgca gctttgctga taaatgaata attctctttg     4440

atgccattta tgagaaaaga cttcaatatc tgttgcctgt catatttaag aaaaattact     4500

gtttctactc tctgtatctg attttaaaag aaaaaactat tcatacctgg cttccaggta     4560

attgactttg aattcttaca agcaaaggtc attgtgtttt tcttgaatag acatctaata     4620

aattttgctt ggaagtatac ttcagttttt cttcttgaca tttatcttta taaaaattgt     4680

gtattttatt ccaacttgtt aaactaagag aaaatgca                             4718


<210>  288
<211>  3338
<212>  DNA
<213>  homo sapiens

<400>  288
gacatcatgg gctattttta ggggttgact ggtagcagat aagtgttgag ctcgggctgg       60

ataagggctc agagttgcac tgagtgtggc tgaagcagcg aggcgggagt ggaggtgcgc      120

ggagtcaggc agacagacag acacagccag ccagccaggt cggcagtata gtccgaactg      180

caaatcttat tttcttttca ccttctctct aactgcccag agctagcgcc tgtggctccc      240

gggctggtgt ttcgggagtg tccagagagc ctggtctcca gccgcccccg ggaggagagc      300

cctgctgccc aggcgctgtt gacagcggcg gaaagcagcg gtacccacgc gcccgccggg      360

ggaagtcggc gagcggctgc agcagcaaag aactttcccg gctgggagga ccggagacaa      420

gtggcagagt cccggagcga acttttgcaa gcctttcctg cgtcttaggc ttctccacgg      480

cggtaaagac cagaaggcgg cggagagcca cgcaagagaa gaaggacgtg cgctcagctt      540

cgctcgcacc ggttgttgaa cttgggcgag cgcgagccgc ggctgccggg cgccccctcc      600

ccctagcagc ggaggagggg acaagtcgtc ggagtccggg cggccaagac ccgccgccgg      660

ccggccactg cagggtccgc actgatccgc tccgcgggga gagccgctgc tctgggaagt      720

gagttcgcct gcggactccg aggaaccgct gcgcccgaag agcgctcagt gagtgaccgc      780

gacttttcaa agccgggtag cgcgcgcgag tcgacaagta agagtgcggg aggcatctta      840

attaaccctg cgctccctgg agcgagctgg tgaggagggc gcagcgggga cgacagccag      900

cgggtgcgtg cgctcttaga gaaactttcc ctgtcaaagg ctccgggggg cgcgggtgtc      960

ccccgcttgc cagagccctg ttgcggcccc gaaacttgtg cgcgcagccc aaactaacct     1020

cacgtgaagt gacggactgt tctatgactg caaagatgga aacgaccttc tatgacgatg     1080

ccctcaacgc ctcgttcctc ccgtccgaga gcggacctta tggctacagt aaccccaaga     1140

tcctgaaaca gagcatgacc ctgaacctgg ccgacccagt ggggagcctg aagccgcacc     1200

tccgcgccaa gaactcggac ctcctcacct cgcccgacgt ggggctgctc aagctggcgt     1260

cgcccgagct ggagcgcctg ataatccagt ccagcaacgg gcacatcacc accacgccga     1320

cccccaccca gttcctgtgc cccaagaacg tgacagatga gcaggagggc ttcgccgagg     1380

gcttcgtgcg cgccctggcc gaactgcaca gccagaacac gctgcccagc gtcacgtcgg     1440

cggcgcagcc ggtcaacggg gcaggcatgg tggctcccgc ggtagcctcg gtggcagggg     1500

gcagcggcag cggcggcttc agcgccagcc tgcacagcga gccgccggtc tacgcaaacc     1560

tcagcaactt caacccaggc gcgctgagca gcggcggcgg ggcgccctcc tacggcgcgg     1620

ccggcctggc ctttcccgcg caaccccagc agcagcagca gccgccgcac cacctgcccc     1680

agcagatgcc cgtgcagcac ccgcggctgc aggccctgaa ggaggagcct cagacagtgc     1740

ccgagatgcc cggcgagaca ccgcccctgt cccccatcga catggagtcc caggagcgga     1800

tcaaggcgga gaggaagcgc atgaggaacc gcatcgctgc ctccaagtgc cgaaaaagga     1860

agctggagag aatcgcccgg ctggaggaaa aagtgaaaac cttgaaagct cagaactcgg     1920

agctggcgtc cacggccaac atgctcaggg aacaggtggc acagcttaaa cagaaagtca     1980

tgaaccacgt taacagtggg tgccaactca tgctaacgca gcagttgcaa acattttgaa     2040

gagagaccgt cgggggctga ggggcaacga agaaaaaaaa taacacagag agacagactt     2100

gagaacttga caagttgcga cggagagaaa aaagaagtgt ccgagaacta aagccaaggg     2160

tatccaagtt ggactgggtt gcgtcctgac ggcgccccca gtgtgcacga gtgggaagga     2220

cttggcgcgc cctcccttgg cgtggagcca gggagcggcc gcctgcgggc tgccccgctt     2280

tgcggacggg ctgtccccgc gcgaacggaa cgttggactt ttcgttaaca ttgaccaaga     2340

actgcatgga cctaacattc gatctcattc agtattaaag gggggagggg gagggggtta     2400

caaactgcaa tagagactgt agattgcttc tgtagtactc cttaagaaca caaagcgggg     2460

ggagggttgg ggaggggcgg caggagggag gtttgtgaga gcgaggctga gcctacagat     2520

gaactctttc tggcctgcct tcgttaactg tgtatgtaca tatatatatt ttttaatttg     2580

atgaaagctg attactgtca ataaacagct tcatgccttt gtaagttatt tcttgtttgt     2640

ttgtttgggt atcctgccca gtgttgtttg taaataagag atttggagca ctctgagttt     2700

accatttgta ataaagtata taattttttt atgttttgtt tctgaaaatt ccagaaagga     2760

tatttaagaa aatacaataa actattggaa agtactcccc taacctcttt tctgcatcat     2820

ctgtagatac tagctatcta ggtggagttg aaagagttaa gaatgtcgat taaaatcact     2880

ctcagtgctt cttactatta agcagtaaaa actgttctct attagacttt agaaataaat     2940

gtacctgatg tacctgatgc tatggtcagg ttatactcct cctcccccag ctatctatat     3000

ggaattgctt accaaaggat agtgcgatgt ttcaggaggc tggaggaagg ggggttgcag     3060

tggagaggga cagcccactg agaagtcaaa catttcaaag tttggattgt atcaagtggc     3120

atgtgctgtg accatttata atgttagtag aaattttaca ataggtgctt attctcaaag     3180

caggaattgg tggcagattt tacaaaagat gtatccttcc aatttggaat cttctctttg     3240

acaattccta gataaaaaga tggcctttgc ttatgaatat ttataacagc attcttgtca     3300

caataaatgt attcaaatac caaaaaaaaa aaaaaaaa                             3338


<210>  289
<211>  3981
<212>  DNA
<213>  homo sapiens

<400>  289
aaagtgagtg agtgagacgg gcagatggag gagggattgt aatggcggca gccggcagct       60

ccctgctctg acccacggca ggcacacagc aacgacccct tccccgcccc tctcccggcc      120

ggcctccgcc ccgcagccag cgcggggcca ccctctccgg cccttccccc agctgtcggc      180

gtctcgccct gcgccccggc cggggcccca cacacaatgg acgagcttgc cggaggcggt      240

ggtggcggcc cggggatggc ggcccctccc cggcagcagc agggacctgg ggggaacctg      300

ggcctttcgc ccggggggaa cggagcggcg ggcggcgggg gtcctccggc ctccgaggga      360

gcgggtcccg cggcaggccc cgagctgtcc cggccgcagc agtacactat cccggggata      420

ctgcactaca tccagcacga gtgggctcgg ttcgagatgg agcgggcgca ctgggaggtg      480

gaacgggccg aactgcaggc ccggattgca tttctacaag gcgaaagaaa aggtcaagag      540

aacctgaaga aggacttagt aagaagaata aagatgttag agtatgcatt aaaacaagaa      600

agggcaaaat atcacaaatt aaaatatggc acggaactga accaaggtga cttgaaaatg      660

ccaacctttg agtcagaaga aaccaaagac acagaggctc ccacagcacc tcagaatagc      720

cagttaacgt ggaagcaagg cagacagctt ttaagacagt atcttcagga agtaggttat      780

acagatacaa tattagatgt acggtctcag cgggtaaggt cattacttgg actatctaat      840

tcagaaccaa atggatcagt agaaacaaag aatttagaac agatcctgaa tggaggtgaa      900

tctcctaagc aaaagggaca agaaataaaa aggtcctctg gtgatgttct tgagacgttc      960

aatttcttag aaaatgccga tgacagtgat gaagatgagg aaaatgacat gatcgaaggc     1020

atcccagaag gaaaagacaa acatcggatg aataaacata aaataggtaa tgaaggttta     1080

gctgctgacc taactgacga tcctgatact gaggaagcac tgaaagaatt tgatttttta     1140

gtgactgctg aagatggtga aggagctgga gaagcacgga gttcggggga tggcacagaa     1200

tgggctgaac caataacgtt tccatctgga ggaggcaagt catttattat gggttctgat     1260

gatgttttgt taagtgtact gggccttgga gaccttgcag acttgacggt aacaaatgat     1320

gcagactata gttatgattt gcctgctaat aaagatgcct ttcgaaagac atggaatccc     1380

aagtatacac tacgtagcca ttttgatgga gtacgggcat tagcttttca tcctgtagaa     1440

cctgtgctgg ttactgcttc tgaggaccat accctgaaac tttggaacct gcaaaaaaca     1500

gttcctgcca aaaagagtgc ctctttagat gtagagccta tctacacatt tagggcccac     1560

atcggccctg ttctgtcatt agctattagt tctaatggag aacagtgttt tagtggtggt     1620

attgatgcaa ccatccagtg gtggaatatg ccgagtccca gtgtagatcc atatgataca     1680

tatgagccaa atgttctagc tggcacttta gttggtcata cagatgcagt ttggggtctt     1740

gcttatagtg gcataaaaaa tcaattactg tcttgttcag cagatggcac tgttaggtta     1800

tggaatccac aagaaaaatt gccatgtatt tgcacttaca atggagataa aaagcatgga     1860

atacctacat cagttgactt tataggctgt gatccagctc atatggtaac ctctttcaac     1920

actggtagtg cagtaattta tgatttagaa acatcacagt cattggtgat actttcatca     1980

caggtagatt ctggtttaca atctaataat catatcaaca gagtagtaag tcatcccaca     2040

cttcctgtta caataactgc tcatgaagat agacacatca aattttttga caataaaacg     2100

ggtaaaatga tccattctat ggtagctcac ttggatgctg ttacaagtct agcagtagat     2160

cctaatggaa tctatttgat gtctggaagc catgactgtt ccatcagatt atggaattta     2220

gacagcaaga catgtgtgca agaaataaca gctcacagaa agaaattgga tgaatcaatt     2280

tatgatgttg ctttccactc gtcaaaagca tatatagcta gtgcaggagc tgatgctctt     2340

gccaaagtat ttgtatgaat caacaaaaac ttgcatcgta acaagatttg cttggacaga     2400

aagagggtct gcatcactgc catcagaaag gttactgata tgacactaca tgtgatctgc     2460

ctggtgaagg ctatctgggg caggcacaaa ttggtggaaa tcacatctta atgtcaagct     2520

cattaagtta actgtaatta ctgtattttg tgggacaaag aaaaaaggac tccagtattt     2580

gtggcctgta ctggatgtga actgagcgta tatctgtttt taggtgtctt taagccaatg     2640

tggagtctga tctttcaaaa aagttttttt ttttctcttc ttcttcttct tttttttttt     2700

tttttttttt tttttggact ctgtgtgctg ccttaggggt taggaatgtg gtgctcttgt     2760

tgggggaagt gagctccaag agtagctttt tttcatctct tagtgatctt ctgtttatcg     2820

gttgaatgcc acagattccc ttttaaactt attttgcttt aaaaaaaaaa aaaaagaaaa     2880

agaaaattta acttaaaata ttttagcatt agttgcacaa aatgtttgga taaaattcta     2940

gtttttataa gtctttttat atatttagcc tgtcacaaca gtgctcaaga ttgtattgaa     3000

gtttttctgc attatacaac cctaaaacac agagatctca ctgacccgtt gccctgtaac     3060

cactttcttt ccttcttttg cctaatacag ctcagctaag tccttccata aagatgctaa     3120

ataactttca tcatcacata aatgtcttca taaaccaagg actattaagt gtattaaaat     3180

gaaacagtgg ggtttagtac tccaaatgaa ctcttaaaga aaaaaactaa tcttggcatc     3240

ctatcactat gtgatatttt gtacatctta ctgtatttac aagtttattt atcaaggatt     3300

atccatcttg ctaatggcct attatttatt tcactttttg ttggtcttta tatcctttta     3360

ttaatgtgct aaaggaacct gtatatctat tttggaactc tttgaatagt ctaaaataga     3420

ctaaaaatgg agtattttat agtttaaatt acaaaccaag gtggttcccc ctaagatata     3480

tatcttggtt taccatgatt ccaaacaaaa ctaacttgtt taaaaatatt tggagtaaag     3540

ttttatttgc attacaaata ggatacaaaa atagttgaat caggatacag aaatctgctg     3600

tgttttgact agttatccct gttttatttt tttagatgtg cttaatttta tggtgtaact     3660

aaagattttg tttgtgtaat gcatgattaa gacaataaag tattttttct agtcttccga     3720

gaaacttttc tgatcagttt gcgagttttg atgagttttg taaggttttt gttttacaaa     3780

ctatgaatca gcaaattttt aagattgtac cacatagcaa acatacagct gttgaaaaat     3840

aatgtatata aaatgcatat aataaatatt aaattgtgta cctgtatgtt actgttggct     3900

acatcatttt gtgttgaata ataaagtgca atactttatt ctccataatt aaactaggaa     3960

atggagattt aaaaaaaaaa a                                               3981


<210>  290
<211>  1102
<212>  DNA
<213>  homo sapiens

<400>  290
attgcaactt ggtctcacag tggcttaggc cagggtggga gcagtgaacg gagtcacaaa       60

agaaattttt cagctgtcct ctctgacacc accccggcct gcctctttgt tgccatgaga      120

gctgcctacc tcttcctgct attcctgcct ggcttgctgg ctcagggcca gtatgacctg      180

gacccgctgc cgccgttccc tgaccacgtc cagtacaccc actatagcga ccagatcgac      240

aacccagact actatgatta tcaagaggtg actcctcggc cctccgagga acagttccag      300

ttccagtccc agcagcaagt ccaacaggaa gtcatcccag ccccaacccc agaaccagga      360

aatgcagagc tggagcccac agagcctggg cctcttgact gccgtgagga acagtacccg      420

tgcacccgcc tctactccat acacaggcct tgcaaacagt gtctcaacga ggtctgcttc      480

tacagcctcc gccgtgtgta cgtcattaac aaggagatct gtgttcgtac agtgtgtgcc      540

catgaggagc tcctccgagc tgacctctgt cgggacaagt tctccaaatg tggcgtgatg      600

gccagcagcg gcctgtgcca atccgtggcg gcctcctgtg ccaggagctg tgggagctgc      660

tagggtggtg ctggcatcct gagtcctggc cctcctggga tctggggccc tcgggccctg      720

cctgacctgg tgcttttttc cccatcccca tgttcctttt attctgtaaa aagttagtgg      780

actgcagccc tgggggttgc aggctgcggt gcctcaggcc cctccttcag cctgtggcca      840

cctctggggc acaatggggg ctccccactg cccagtctgc ccctcgggtt gggggagtat      900

cccaggcctc tctgtgggac ctgggcccct gacgggcctt ctcagcccgt tttgaggaca      960

gacagtcccc cgaggtaggc tacatccccc caccccagct ggtctgcttg gatttcctac     1020

agcccccgtg ggcatggacc acctttattt tatacaaaat taaaaacaag tttttacaaa     1080

aaaaaaaaaa aaaaaaaaaa aa                                              1102


<210>  291
<211>  2588
<212>  DNA
<213>  homo sapiens

<400>  291
gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt       60

ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt      120

gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggccagac      180

tgccttccgg gtcactgcca tggaggagcc gcagtcagat cctagcgtcg agccccctct      240

gagtcaggaa acattttcag acctatggaa actacttcct gaaaacaacg ttctgtcccc      300

cttgccgtcc caagcaatgg atgatttgat gctgtccccg gacgatattg aacaatggtt      360

cactgaagac ccaggtccag atgaagctcc cagaatgcca gaggctgctc cccccgtggc      420

ccctgcacca gcagctccta caccggcggc ccctgcacca gccccctcct ggcccctgtc      480

atcttctgtc ccttcccaga aaacctacca gggcagctac ggtttccgtc tgggcttctt      540

gcattctggg acagccaagt ctgtgacttg cacgtactcc cctgccctca acaagatgtt      600

ttgccaactg gccaagacct gccctgtgca gctgtgggtt gattccacac ccccgcccgg      660

cacccgcgtc cgcgccatgg ccatctacaa gcagtcacag cacatgacgg aggttgtgag      720

gcgctgcccc caccatgagc gctgctcaga tagcgatggt ctggcccctc ctcagcatct      780

tatccgagtg gaaggaaatt tgcgtgtgga gtatttggat gacagaaaca cttttcgaca      840

tagtgtggtg gtgccctatg agccgcctga ggttggctct gactgtacca ccatccacta      900

caactacatg tgtaacagtt cctgcatggg cggcatgaac cggaggccca tcctcaccat      960

catcacactg gaagactcca gtggtaatct actgggacgg aacagctttg aggtgcgtgt     1020

ttgtgcctgt cctgggagag accggcgcac agaggaagag aatctccgca agaaagggga     1080

gcctcaccac gagctgcccc cagggagcac taagcgagca ctgcccaaca acaccagctc     1140

ctctccccag ccaaagaaga aaccactgga tggagaatat ttcacccttc agatccgtgg     1200

gcgtgagcgc ttcgagatgt tccgagagct gaatgaggcc ttggaactca aggatgccca     1260

ggctgggaag gagccagggg ggagcagggc tcactccagc cacctgaagt ccaaaaaggg     1320

tcagtctacc tcccgccata aaaaactcat gttcaagaca gaagggcctg actcagactg     1380

acattctcca cttcttgttc cccactgaca gcctcccacc cccatctctc cctcccctgc     1440

cattttgggt tttgggtctt tgaacccttg cttgcaatag gtgtgcgtca gaagcaccca     1500

ggacttccat ttgctttgtc ccggggctcc actgaacaag ttggcctgca ctggtgtttt     1560

gttgtgggga ggaggatggg gagtaggaca taccagctta gattttaagg tttttactgt     1620

gagggatgtt tgggagatgt aagaaatgtt cttgcagtta agggttagtt tacaatcagc     1680

cacattctag gtaggggccc acttcaccgt actaaccagg gaagctgtcc ctcactgttg     1740

aattttctct aacttcaagg cccatatctg tgaaatgctg gcatttgcac ctacctcaca     1800

gagtgcattg tgagggttaa tgaaataatg tacatctggc cttgaaacca ccttttatta     1860

catggggtct agaacttgac ccccttgagg gtgcttgttc cctctccctg ttggtcggtg     1920

ggttggtagt ttctacagtt gggcagctgg ttaggtagag ggagttgtca agtctctgct     1980

ggcccagcca aaccctgtct gacaacctct tggtgaacct tagtacctaa aaggaaatct     2040

caccccatcc cacaccctgg aggatttcat ctcttgtata tgatgatctg gatccaccaa     2100

gacttgtttt atgctcaggg tcaatttctt ttttcttttt tttttttttt tttctttttc     2160

tttgagactg ggtctcgctt tgttgcccag gctggagtgg agtggcgtga tcttggctta     2220

ctgcagcctt tgcctccccg gctcgagcag tcctgcctca gcctccggag tagctgggac     2280

cacaggttca tgccaccatg gccagccaac ttttgcatgt tttgtagaga tggggtctca     2340

cagtgttgcc caggctggtc tcaaactcct gggctcaggc gatccacctg tctcagcctc     2400

ccagagtgct gggattacaa ttgtgagcca ccacgtccag ctggaagggt caacatcttt     2460

tacattctgc aagcacatct gcattttcac cccacccttc ccctccttct ccctttttat     2520

atcccatttt tatatcgatc tcttatttta caataaaact ttgctgccac ctgtgtgtct     2580

gaggggtg                                                              2588


<210>  292
<211>  3747
<212>  DNA
<213>  homo sapiens

<400>  292
gggcctactc tgccgccgcc gccgcccgcc cgctccagcc gccgccgccg ccgccaccgc       60

cctccaggct ccgggacccg gcccgcgcca ccgcccccgt gcgcgccccg ccgccgccgc      120

cttcgccttc gccttttgtt tcctccgctc cggcgccccc gccccggctc gcgctttgca      180

ggggacgcag cgcgcgcccc cagcgggccc gggaaaagcc gcggcgcgcg cgcgcgcctg      240

cgcggcggac ccctccttct cctccccgcg tgcgcgtgcc cttcttggct gcgcgccggc      300

gccgcctggc gggcgggagg ggaggtggca ggcgcgtttg caggaggggc gcacctcttc      360

gctcgcgcac ccccccggaa ggtagaccgg gaaggggagg cgggcgggcg gagaggagag      420

agtggcgcgc agtccagcga gggcgggggt tggctatgtg gggggtggtg caccccgcag      480

tctagacagt ctgatccggg ctgggggcgt gtacactcgg cgcacctgcg agactacaga      540

gcctcgggcc ggcacgtgtg gggagtgtgg acacgtctgc tgcgccccgc ttctcgctgc      600

tgaggggaag ggagggggcg ggcaggtgca gcggccgggc tagtgggagg gggcggcggc      660

catggagcgg gtgaacgacg cttcgtgcgg cccgtctggc tgctacacat accaggtgag      720

cagacacagc acggagatgc tgcacaacct gaaccagcag cgcaaaaacg gcgggcgctt      780

ctgcgacgtg ctcttgcggg taggcgacga gagcttccca gcgcaccgcg ccgtgctggc      840

cgcctgcagc gagtactttg agtcggtgtt cagcgcccag ttgggcgacg gcggagctgc      900

ggacgggggt ccggctgatg tagggggcgc gacggcagca ccaggcggcg gggccggggg      960

cagccgggag ctggagatgc acactatcag ctccaaggta tttggggaca ttctggactt     1020

cgcctacact tcccgcatcg tggtgcgctt ggagagcttt cccgaactca tgacggccgc     1080

caagttcctg ctgatgaggt cggttatcga gatctgccag gaagtcatca aacagtccaa     1140

cgtacagatc ctggtacccc ctgcccgcgc cgatataatg ctctttcgcc cccctgggac     1200

ctcggacttg ggcttccctt tggacatgac caacggggca gccttggcag ccaacagcaa     1260

tggcatcgcc ggcagcatgc agccagagga ggaggcagct cgggcggctg gtgcagccat     1320

tgcaggccaa gcctctttgc ctgtgttacc tggggtggac cgcttgccca tggtggctgg     1380

acccctatcc ccccaactgc tgacttcccc attccccagt gtggcatcca gtgcccctcc     1440

cctgactggc aagcgaggcc ggggccgccc aaggaaggcc aacctgctgg actcaatgtt     1500

tgggtcccca gggggcctga gggaggcagg catccttcca tgcggtctat gtggtaaggt     1560

gttcactgat gccaaccggc tccggcagca cgaggcccag cacggtgtca ccagcctcca     1620

gctgggctac atcgaccttc ctcctccgag gctgggtgag aatgggctac ccatctctga     1680

agaccccgac ggcccccgaa agaggagccg gaccaggaag caggtggctt gtgagatctg     1740

cggcaagatc ttccgtgatg tgtatcatct taaccggcac aagctgtccc actctgggga     1800

gaagccctac tcctgccctg tgtgtgggtt gcggttcaag agaaaagacc gcatgtccta     1860

ccatgtgcgg tcccatgatg ggtccgtggg caagccttac atctgccaga gctgtgggaa     1920

aggcttctcc aggcctgatc acttgaacgg acatatcaag caggtgcaca cttctgagcg     1980

gcctcacaag tgtcagacct gcaatgcttc ttttgccacc cgagaccgtc tgcgctccca     2040

cctggcctgt catgaagaca aggtgccctg ccaggtgtgt gggaagtact tgcgggcagc     2100

atacatggca gaccacctga agaagcacag cgaggggccc agcaacttct gcagtatctg     2160

taaccgaggt ctccaggcac caggagccca tcctgaatgg gggagcagcg ttccactgcg     2220

ccaggaccta tggcaacaaa gaaggccaga aatgctcaca tcaggatccg attgagagct     2280

ctgactccta tggtgacctc tcagatgcca gcgacctgaa gacgccagag aagcagagtg     2340

ccaatggctc tttctcctgc gacatggcag tccccaaaaa caaaatggag tctgatgggg     2400

agaagaagta cccatgccct gaatgtggga gcttcttccg ctctaagtcc tacttgaaca     2460

aacacatcca gaaggtgcat gtccgggctc tcgggggccc cctgggggac ctgggccctg     2520

cccttggctc acctttctct cctcagcaga acatgtctct cctcgagtcc tttgggtttc     2580

agattgttca gtcggcattt gcgtcatctt tagtagatcc tgaggttgac cagcagccca     2640

tggggcctga agggaaatga ggcagctgct gtgtccccac ggaaacaacc atctggggac     2700

tgctgggaaa tgctgtgaat gcggagggaa gtgatgtttg ggttctgtag ctgagagatt     2760

tttattcatt tttaactgcc ccccaacccc actccaactc cttctccacc acccattctc     2820

ccaatggtct ttagaaatag attttcatct gatattctgc agaaatatca atgagacttg     2880

gtatgggaca ggggcagaaa acactacata ggcctccaag gcaaaaccag tcccagtttc     2940

tttaatggga agaagctgga attcctggtg ctcaattctt agtgacccca atcctatacc     3000

caaatctatg atattctggg acctcagtga ttttggtccc ctcccacttc tctagttcgt     3060

catcctccct tcccatatcc ttcaaaagaa ccacactagg gtctccacct acttatacaa     3120

tgcggatgcc caactgtttt taaggaagcc agaagcatcc catggaccat ggggtgagtg     3180

tcctccaaga gccccctgag ctcagccctc tgcctggagg gctccagacc tttctgagcc     3240

ctgcttggag gcgagcattt tcactgctag gacaagctca gctgttgagg acacccccac     3300

cccaaatttc agttcttacg tgattttaac cattcaacat gctgttgggt tttaattctc     3360

taattattat tattattgtt attatttttt aggaccagtt gtagtgaatt gctactgaaa     3420

gctatcccag gtgatacaga gctctttgta aaccgcagtc acacattagg gttagtatta     3480

aactttgttt agatgtacca taattaactt ggctagttga ttgtttgaag tctatggaag     3540

aaatagtttt atgcaaaatt ttaaaaaatg ccagtctggt cagggaagta gggggtttca     3600

atgctgttgg gaaccaggaa ggtgggacag ccggcaggta gggacattgt gtacctcagt     3660

tgtgtcacat gtgagcaagc ccaggttgac cttgtgatgt gaattgatct gatcagactg     3720

tattaaaaat gttagtacat tactcta                                         3747


<210>  293
<211>  3812
<212>  DNA
<213>  homo sapiens

<400>  293
gggcctactc tgccgccgcc gccgcccgcc cgctccagcc gccgccgccg ccgccaccgc       60

cctccaggct ccgggacccg gcccgcgcca ccgcccccgt gcgcgccccg ccgccgccgc      120

cttcgccttc gccttttgtt tcctccgctc cggcgccccc gccccggctc gcgctttgca      180

ggggacgcag cgcgcgcccc cagcgggccc gggaaaagcc gcggcgcgcg cgcgcgcctg      240

cgcggcggac ccctccttct cctccccgcg tgcgcgtgcc cttcttggct gcgcgccggc      300

gccgcctggc gggcgggagg ggaggtggca ggcgcgtttg caggaggggc gcacctcttc      360

gctcgcgcac ccccccggaa ggtagaccgg gaaggggagg cgggcgggcg gagaggagag      420

agtggcgcgc agtccagcga gggcgggggt tggctatgtg gggggtggtg caccccgcag      480

tctagacagt ctgatccggg ctgggggcgt gtacactcgg cgcacctgcg agactacaga      540

gcctcgggcc ggcacgtgtg gggagtgtgg acacgtctgc tgcgccccgc ttctcgctgc      600

tgaggggaag ggagggggcg ggcaggtgca gcggccgggc tagtgggagg gggcggcggc      660

catggagcgg gtgaacgacg cttcgtgcgg cccgtctggc tgctacacat accaggtgag      720

cagacacagc acggagatgc tgcacaacct gaaccagcag cgcaaaaacg gcgggcgctt      780

ctgcgacgtg ctcttgcggg taggcgacga gagcttccca gcgcaccgcg ccgtgctggc      840

cgcctgcagc gagtactttg agtcggtgtt cagcgcccag ttgggcgacg gcggagctgc      900

ggacgggggt ccggctgatg tagggggcgc gacggcagca ccaggcggcg gggccggggg      960

cagccgggag ctggagatgc acactatcag ctccaaggta tttggggaca ttctggactt     1020

cgcctacact tcccgcatcg tggtgcgctt ggagagcttt cccgaactca tgacggccgc     1080

caagttcctg ctgatgaggt cggttatcga gatctgccag gaagtcatca aacagtccaa     1140

cgtacagatc ctggtacccc ctgcccgcgc cgatataatg ctctttcgcc cccctgggac     1200

ctcggacttg ggcttccctt tggacatgac caacggggca gccttggcag ccaacagcaa     1260

tggcatcgcc ggcagcatgc agccagagga ggaggcagct cgggcggctg gtgcagccat     1320

tgcaggccaa gcctctttgc ctgtgttacc tggggtggac cgcttgccca tggtggctgg     1380

acccctatcc ccccaactgc tgacttcccc attccccagt gtggcatcca gtgcccctcc     1440

cctgactggc aagcgaggcc ggggccgccc aaggaaggcc aacctgctgg actcaatgtt     1500

tgggtcccca gggggcctga gggaggcagg catccttcca tgcggtctat gtggtaaggt     1560

gttcactgat gccaaccggc tccggcagca cgaggcccag cacggtgtca ccagcctcca     1620

gctgggctac atcgaccttc ctcctccgag gctgggtgag aatgggctac ccatctctga     1680

agaccccgac ggcccccgaa agaggagccg gaccaggaag caggtggctt gtgagatctg     1740

cggcaagatc ttccgtgatg tgtatcatct taaccggcac aagctgtccc actctgggga     1800

gaagccctac tcctgccctg tgtgtgggtt gcggttcaag agaaaagacc gcatgtccta     1860

ccatgtgcgg tcccatgatg ggtccgtggg caagccttac atctgccaga gctgtgggaa     1920

aggcttctcc aggcctgatc acttgaacgg acatatcaag caggtgcaca cttctgagcg     1980

gcctcacaag tgtcagacct gcaatgcttc ttttgccacc cgagaccgtc tgcgctccca     2040

cctggcctgt catgaagaca aggtgccctg ccaggtgtgt gggaagtact tgcgggcagc     2100

atacatggca gaccacctga agaagcacag cgaggggccc agcaacttct gcagtatctg     2160

taaccgaggt ttctcctctg cctcctactt aaaggtccat gttaaaaccc accacggtgt     2220

tccccttccc caggtctcca ggcaccagga gcccatcctg aatgggggag cagcgttcca     2280

ctgcgccagg acctatggca acaaagaagg ccagaaatgc tcacatcagg atccgattga     2340

gagctctgac tcctatggtg acctctcaga tgccagcgac ctgaagacgc cagagaagca     2400

gagtgccaat ggctctttct cctgcgacat ggcagtcccc aaaaacaaaa tggagtctga     2460

tggggagaag aagtacccat gccctgaatg tgggagcttc ttccgctcta agtcctactt     2520

gaacaaacac atccagaagg tgcatgtccg ggctctcggg ggccccctgg gggacctggg     2580

ccctgccctt ggctcacctt tctctcctca gcagaacatg tctctcctcg agtcctttgg     2640

gtttcagatt gttcagtcgg catttgcgtc atctttagta gatcctgagg ttgaccagca     2700

gcccatgggg cctgaaggga aatgaggcag ctgctgtgtc cccacggaaa caaccatctg     2760

gggactgctg ggaaatgctg tgaatgcgga gggaagtgat gtttgggttc tgtagctgag     2820

agatttttat tcatttttaa ctgcccccca accccactcc aactccttct ccaccaccca     2880

ttctcccaat ggtctttaga aatagatttt catctgatat tctgcagaaa tatcaatgag     2940

acttggtatg ggacaggggc agaaaacact acataggcct ccaaggcaaa accagtccca     3000

gtttctttaa tgggaagaag ctggaattcc tggtgctcaa ttcttagtga ccccaatcct     3060

atacccaaat ctatgatatt ctgggacctc agtgattttg gtcccctccc acttctctag     3120

ttcgtcatcc tcccttccca tatccttcaa aagaaccaca ctagggtctc cacctactta     3180

tacaatgcgg atgcccaact gtttttaagg aagccagaag catcccatgg accatggggt     3240

gagtgtcctc caagagcccc ctgagctcag ccctctgcct ggagggctcc agacctttct     3300

gagccctgct tggaggcgag cattttcact gctaggacaa gctcagctgt tgaggacacc     3360

cccaccccaa atttcagttc ttacgtgatt ttaaccattc aacatgctgt tgggttttaa     3420

ttctctaatt attattatta ttgttattat tttttaggac cagttgtagt gaattgctac     3480

tgaaagctat cccaggtgat acagagctct ttgtaaaccg cagtcacaca ttagggttag     3540

tattaaactt tgtttagatg taccataatt aacttggcta gttgattgtt tgaagtctat     3600

ggaagaaata gttttatgca aaattttaaa aaatgccagt ctggtcaggg aagtaggggg     3660

tttcaatgct gttgggaacc aggaaggtgg gacagccggc aggtagggac attgtgtacc     3720

tcagttgtgt cacatgtgag caagcccagg ttgaccttgt gatgtgaatt gatctgatca     3780

gactgtatta aaaatgttag tacattactc ta                                   3812


<210>  294
<211>  3218
<212>  DNA
<213>  homo sapiens

<400>  294
cttttagttt ctcttctttc taaagaaggc tcgcggagcc cggctggaga acctcaccct       60

cgccgagcct agaaccgaga gggggccacc ccaggcggtc accagcagat ttgcccgcgc      120

gttctctttc tttccaccca gttgcccttg cggccggctg taaacctgcc actaggaccc      180

ggtcggtgag atctagcctc ttgacctgag agccgagagt ggatcgctgg gctgggctaa      240

cggcgacgga gagcgcgccc tcgctgactc cgggcgcgcc cagcagtagc accgcccgcg      300

cccgcccctg gacacttgta agtttcgatt tccgatttcc gcggaaccga gtcccgcgcc      360

gcggcagagc cagcacagcc agcgcgccat ggcggacccg gaggtgtgct gcttcatcac      420

caaaatcctg tgcgcccacg ggggccgcat ggccctggac gcgctgctcc aggagatcgc      480

gctgtctgag ccgcagctct gtgaggtgct gcaggtggcc gggcccgacc gctttgtggt      540

gttggagacc ggcggcgagg ccgggatcac ccgatcggtg gtggccacca ctcgagcccg      600

ggtctgccgt cgcaagtact gccagagacc ctgcgataac ctgcatctct gcaaactcaa      660

cttgctgggc cggtgcaact attcgcagtc cgagcggaat ttatgcaaat attctcatga      720

ggttctctca gaagagaact tcaaagtcct gaaaaatcac gaactctctg gactgaacaa      780

agaggaatta gcagtgctcc tcctccaaag tgatcctttt tttatgcccg agatatgcaa      840

aagttataag ggagagggtc ggcagcagat ttgtaaccag cagccaccgt gttcaagact      900

ccacatctgt gaccacttca cccgagggaa ctgtcgtttt cccaactgcc tccggtccca      960

taacctgatg gacagaaagg tgctggccat catgagggag cacgggctga accccgacgt     1020

ggtccagaac atccaggaca tctgcaacag caagcacatg cagaagaatc ccccagggcc     1080

cagagctcct tcttcacatc gtagaaacat ggcatatagg gctagaagca agagtagaga     1140

tcggttcttt cagggcagcc aagaatttct tgcgtctgct tcagcgtctg ctgagaggtc     1200

ctgcacacct agtccagatc agatcagcca cagggcttcc ctggaggacg cgcctgtgga     1260

cgatctcacc cgcaagttca cgtatctggg gagtcaggat cgcgctcggc ctccctcagg     1320

ctcgtccaag gctactgatc ttggaggaac aagtcaggcc gggacaagcc agaggttttt     1380

agagaacggc agtcaagagg acctcttgca tggaaatcca ggcagcactt accttgcttc     1440

caattcaaca tcagccccca actggaagag cctcacatcc tggacgaatg accaaggcgc     1500

caggagaaag actgtgtttt ctcccacgct acctgccgcc cgctcttctc ttggctctct     1560

gcaaacacct gaagctgtga ccaccagaaa gggcacaggc ttgctttcct cagactacag     1620

gatcatcaat ggcaaaagtg gaactcagga catccagcct ggccctcttt ttaataataa     1680

tgctgatgga gtggccacag atataacttc taccagatcc ttaaattaca aaagcactag     1740

cagcggtcac agagaaatat catcacctag gattcaggat gctggacctg cttcccgaga     1800

tgtccaggcc actggcagaa tcgcagatga tgctgaccca agagtagcac ttgttaacga     1860

ttctttatct gatgtcacaa gtaccacatc ttctagggtg gatgatcatg actcagagga     1920

aatttgtctt gaccatctgt gtaagggttg tccgcttaat ggtagctgca gcaaagtcca     1980

cttccatctg ccttaccggt ggcagatgct tattggtaaa acctggacgg actttgagca     2040

catggagacg atcgagaaag gctactgtaa ccccggaatc cacctctgtt ctgtaggaag     2100

ttatacaatc aattttcggg taatgagttg tgattccttt cccatccgac gcctctccac     2160

tccttcttct gtcaccaagc cagccaattc tgtcttcacc accaaatgga tttggtattg     2220

gaagaatgaa tctggcacat ggattcagta tggagaagag aaagacaaac ggaaaaattc     2280

aaacgtcgac tcttcatacc tggagtctct ctatcaatcc tgtccgaggg gagttgtgcc     2340

atttcaggcg ggctcacgga actatgagct gagtttccaa gggatgattc agacaaacat     2400

agcttccaaa actcaaaagg atgtcatcag aagaccaaca tttgtgcctc agtggtatgt     2460

gcagcagatg aagagagggc cagagtaagt gttctgaagc agctgtttgc tgacagatgc     2520

ttgagatgtt catgccctgg gctcatcaag tcactcgtga atctggagcc tgttttcctg     2580

aaaagttcct gtttgcatta ctctgcagtt tccatttgca ttatcgatga gtaagatgct     2640

tgttaagcag catggtgtga ctgaaaggat actagatcgg aaaatgaatt ttctttctga     2700

aagggaagtc tgagcgagtc tcctaaatac tctgggcttt agcttctcca gctgtgaaga     2760

gctggattga tgcagtacac ctaaggaata atcatatata ctgggttttt gttttgctgt     2820

ggattctttt tttttttttt ttttttagag ggggtctcac tttgttgccc aggctggtct     2880

tgaactcctg agctcaagtg atcctcctac ctcagtctcc caaagtgctg ggattacagg     2940

catgagccac cgtgcctggc tttgctgtgg attcttttgg gtgtcttttg ttttcctaca     3000

cgatttatag aggatgaggg gcggagaaag agatagaaaa aagggatgag ctagctgtta     3060

gagcaagggt tttggtgaga gataatattg attgaaggga ttttaaagga aatgttgctg     3120

tgggggattc attgtaactc tccttgtgaa ctgctcagta aactctacat tgttcatgaa     3180

caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                             3218


<210>  295
<211>  1431
<212>  DNA
<213>  homo sapiens

<400>  295
ccgtgaagtg ggcggagcga gcgatttgaa cgcgagcggc gcggacttct gccaagcacc       60

ggctcatgtg aggctcgcgg cacagcgttc tctgggctcc ccagaagcca gcctttcgct      120

cccggacccg gcagcccgag caggagccgt gggaccgggc gccagcaccc tctgcggcgt      180

gtcatgggcc cgcgccgccg gagccgaaag cccgaggccc cgaggaggcg cagcccgagc      240

ccgaccccga cccccggccc ctcccggcgg ggcccctcct taggcgcttc ctcccatcaa      300

cacagtcggc ggagacaagg ttggctaaag gagatccgaa agcttcagaa gagcacacac      360

ctcttgataa ggaagctgcc cttcagccgc ctggcaagag aaatatgtgt taaattcact      420

cgtggtgtgg acttcaattg gcaagcccag gccctattgg ccctacaaga ggcagcagaa      480

gcatttctag ttcatctctt tgaggacgcc tatctcctca ccttacatgc aggccgagtt      540

actctcttcc caaaggatgt gcaactggcc cggaggatcc ggggccttga ggagggactc      600

ggctgagctc ctgcacccag tgtttctgtc agtctttcct gctcagccag gggggatgat      660

accggggact ctccagagcc atgactagat ccaatggatt ctgcgatgct gtctggactt      720

tgctgtctct gaacagtatg tgtgtgttgc tttaaatatt tttctttttt ttgagaagga      780

gaagactgca tgactttcct ctgtaacaga ggtaatatat gagacaatca acaccgttcc      840

aaaggcctga aaataatttt cagataaaga gactccaagg ttgactttag tttgtgagtt      900

actcatgtga ctatttgagg attttgaaaa catcagattt gctgtggtat gggagaaaag      960

gctatgtact tattatttta gctctttctg taatatttac attttttacc atatgtacat     1020

ttgtactttt attttacaca taagggaaaa aataagacca ctttgagcag ttgcctggaa     1080

ggctgggcat ttccatcata tagacctctg cccttcagag tagcctcacc attagtggca     1140

gcatcatgta actgagtgga ctgtgcttgt caacggatgt gtagcttttc agaaacttaa     1200

ttggggatga atagaaaacc tgtaagcttt gatgttctgg ttacttctag taaattcctg     1260

tcaaaatcaa ttcagaaatt ctaacttgga gaatttaaca ttttactctt gtaaatcata     1320

gaagatgtat cataacagtt cagaatttta aagtacattt tcgatgcttt tatgggtatt     1380

tttgtagttt ctttgtagag agataataaa aatcaaaata tttaatgaaa a              1431


<210>  296
<211>  3384
<212>  DNA
<213>  homo sapiens

<400>  296
gtgagttcca ggtgggaagg cagttatgac agttgagaag tagtagaaga cacggaaggc       60

acagaaggca gacttcgctc agcacaaaga attttctgat aaccatactg gcaaaatgaa      120

ctgggctgcc ttcggagggt ctgaattctt catcccagaa ggcattcaga tagattcgag      180

atgcccacta agcagaaata tcacggaatg gtaccattac tatggcattg cagtgaaaga      240

aagctcccaa tattatgatg tgatgtattc caagaaagga gctgcctggg tgagtgagac      300

gggcaagaaa gaagtgagca aacagacagt ggcatattca ccccggtcca aactcggaac      360

actgctgcca gaatttccca atgtcaaaga tctaaatctg ccagccagcc tgcctgagga      420

gaaggtttct acctttatta tgatgtacag aacacactgt cagagaatac tggacactgt      480

aataagagcc aactttgatg aggttcaaag tttccttctg cacttttggc aaggaatgcc      540

gccccacatg ctgcctgtgc tgggctcctc cacggtggtg aacattgtcg gcgtgtgtga      600

ctccatcctc tacaaagcta tctccggggt gctgatgccc actgtgctgc aggcattacc      660

tgacagctta actcaggtga ttcgaaagtt tgccaagcaa ctggatgagt ggctaaaagt      720

ggctctccac gacctcccag aaaacttgcg aaacatcaag ttcgaattgt cgagaaggtt      780

ctcccaaatt ctgagacggc aaacatcact aaatcatctc tgccaggcat ctcgaacagt      840

gatccacagt gcagacatca cgttccaaat gctggaagac tggaggaacg tggacctgaa      900

cagcatcacc aagcaaaccc tttacaccat ggaagactct cgcgatgagc accggaaact      960

catcacccaa ttatatcagg agtttgacca tctcttggag gagcagtctc ccatcgagtc     1020

ctacattgag tggctggata ccatggttga ccgctgtgtt gtgaaggtgg ctgccaagag     1080

acaagggtcc ttgaagaaag tggcccagca gttcctcttg atgtggtcct gtttcggcac     1140

aagggtgatc cgggacatga ccttgcacag cgcccccagc ttcgggtctt ttcacctaat     1200

tcacttaatg tttgatgact acgtgctcta cctgttagaa tctctgcact gtcaggagcg     1260

ggccaatgag ctcatgcgag ccatgaaggg agaaggaagc actgcagaag tccgagaaga     1320

gatcatcttg acagaggctg ccgcaccaac cccttcacca gtgccatcgt tttctccagc     1380

aaaatctgcc acatctgtgg aagtgccacc tccctcttcc cctgttagca atccttcccc     1440

tgagtacact ggcctcagca ctacaggagc aatgcagtct tacacgtggt ctctaacata     1500

cacagtgacg acggctgctg ggtccccagc tgagaactcc caacagctgc cctgtatgag     1560

gaacactcat gtgccttctt cctccgtcac acacaggata ccagtttatc cccacagaga     1620

ggaacatgga tacacgggaa gctataacta tgggagctat ggcaaccagc atcctcaccc     1680

catgcagagc cagtatccgg ccctccctca tgacacagct atctctgggc cactccacta     1740

tgccccttac cacaggagct ctgcacagta cccttttaat agccccactt cccggatgga     1800

accttgtttg atgagcagta ctcccagact gcatcctacc ccagtcactc cccgctggcc     1860

agaggtgccc tcagccaaca cgtgctacac aagcccgtct gtgcattctg cgaggtacgg     1920

aaactctagt gacatgtata cacctctgac aacgcgcagg aattctgaat atgagcacat     1980

gcaacacttt cctggctttg cttacatcaa cggagaggcc tctacaggat gggctaaatg     2040

actgctatca taggcatcca tatttaatat taataataat aattaataat aataataaac     2100

ccaacaccca tcccccagaa gactttatct ctatacattg taactcatgg gctattccta     2160

agtgcccatt ttcctaatga acatgaggat gggatcaatg tgggatgaat aaactttagt     2220

tcagaaacag gacttactaa aagtcagtgg gactgggttt ctgtagccaa gccagacttg     2280

actgtttctg tagagcacta tctcgggcag gccattctgt gccttttccc tctgttccat     2340

gactttgctt tgtgttggca accacttcta gtaagctact gattttcctg ttgacaaaat     2400

ctctttagtc ttgaaggatg gatactggag acagaatctg gtttgtgttc ttggatgggc     2460

acataattta ccaagagcat tcaccttgcc atctgtcttg tcattgtact gtacaaggaa     2520

cagccctcag acgtgttctg cacatccctt cttcctggtg gtaccatccc tatttcctgg     2580

agcaccaggg ctaaatgggg agctatctgg aaactctaga ttttctgtca tacccacatc     2640

tgtcacagta cctgcattgt cttggaatgt aagcactgtc ttgagggaag gaagaggtct     2700

gttctgtatt gccttaagtt gattgaggtt tgtaggagac tggttcttct acatacaagg     2760

atttgtctta agtttgcaca atggctagtg tcagcaaaag gcaggagagg gtttttgttt     2820

tttttttaag ttctatgaga atgtggattt atggcattga gtatcacact cagctctgct     2880

gtgttaactt tgtgaaactg gatggaacaa actttaactt accaagcacc aagtgtgaaa     2940

gtgactttca cggttccttc ataaaactat aataatatcc gacactttga tagaaaaaaa     3000

ttcaaagctg tgcctttgag cctatactat actgtgtatg tgtggaaata aaaatgtatt     3060

gtacttttgg agaatttttt gtaggcattt ttctgtcaga tttgtagtaa tttgtgaggt     3120

ttgttagaga ttaatatagg ttttctttct gtattataaa atgcaccaag caattatggt     3180

ggacctatta ccctatgggt aagaaataaa tggaaatatg acatcggatg tttcagcaac     3240

tgttctgtaa ataaaatctt tgatcacacc actcagtgtg ataattgtgt ctacagctaa     3300

aatggaaata gttttatctg tacagttgtg caagatatga atggtttcac actcaaataa     3360

aaaatattga aacgacaaaa aaaa                                            3384


<210>  297
<211>  2483
<212>  DNA
<213>  homo sapiens

<400>  297
tcgtcggagc gcggctcagc ggcgcggcgg agactcggca cggcggcggc caggcgcagg       60

cgggcgggcg gagcagcgga cggcgccgag gccgccccac gcgccgggct cgcggcggcg      120

cagcgcgccg gagtggtcgg ggcccgcggc cgctcgcgcc tctcgatggg cagctcgcac      180

ttgctcaaca agggcctgcc gcttgtaaga ctttgacccc gacgcaggct tcagtgattg      240

ccgcggatca gaagcctgag cactttggct cgagacaatt aaggacgtgg gatgaggctc      300

cgagacagga cgcggttctg cctggggatc ctgaagataa aaagctttga aaagtcgaat      360

tcatggtcgt ggaagctgag cccatattaa gagatgtcag gcgtccgacc tccgatcatg      420

aacgggcccc tgcacccgcg gcccctggtg gcattgctgg atggccggga ctgcacagtg      480

gagatgccca tcctgaagga cgtggccact gtggccttct gcgacgcgca gtccacgcag      540

gagatccatg agaaggtcct gaacgaggct gtgggggccc tgatgtacca caccatcact      600

ctcaccaggg aggacctgga gaagttcaaa gccctccgca tcatcgtccg gattggcagt      660

ggttttgaca acatcgacat caagtcggcc ggggatttag gcattgccgt ctgcaacgtg      720

cccgcggcgt ctgtggagga gacggccgac tcgacgctgt gccacatcct gaacctgtac      780

cggcgggcca cctggctgca ccaggcgctg cgggagggca cacgagtcca gagcgtcgag      840

cagatccgcg aggtggcgtc cggcgctgcc aggatccgcg gggagacctt gggcatcatc      900

ggacttggtc gcgtggggca ggcagtggcg ctgcgggcca aggccttcgg cttcaacgtg      960

ctcttctacg acccttactt gtcggatggc gtggagcggg cgctggggct gcagcgtgtc     1020

agcaccctgc aggacctgct cttccacagc gactgcgtga ccctgcactg cggcctcaac     1080

gagcacaacc accacctcat caacgacttc accgtcaagc agatgagaca aggggccttc     1140

ctggtgaaca cagcccgggg tggcctggtg gatgagaagg cgctggccca ggccctgaag     1200

gagggccgga tccgcggcgc ggccctggat gtgcacgagt cggaaccctt cagctttagc     1260

cagggccctc tgaaggatgc acccaacctc atctgcaccc cccatgctgc atggtacagc     1320

gagcaggcat ccatcgagat gcgagaggag gcggcacggg agatccgcag agccatcaca     1380

ggccggatcc cagacagcct gaagaactgt gtcaacaagg accatctgac agccgccacc     1440

cactgggcca gcatggaccc cgccgtcgtg caccctgagc tcaatggggc tgcctatagg     1500

taccctccgg gcgtggtggg cgtggccccc actggcatcc cagctgctgt ggaaggtatc     1560

gtccccagcg ccatgtccct gtcccacggc ctgccccctg tggcccaccc gccccacgcc     1620

ccttctcctg gccaaaccgt caagcccgag gcggatagag accacgccag tgaccagttg     1680

tagcccggga ggagctctcc agcctcggcg cctgggcaga gggcccggaa accctcggac     1740

cagagtgtgt ggaggaggca tctgtgtggt ggccctggca ctgcagagac tggtccgggc     1800

tgtcaggagg cgggaggggg cagcgctggg cctcgtgtcg cttgtcgtcg tccgtcctgt     1860

gggcgctctg ccctgtgtcc ttcgcgttcc tcgttaagca gaagaagtca gtagttattc     1920

tcccatgaac gttcttgtct gtgtacagtt tttagaacat tacaaaggat ctgtttgctt     1980

agctgtcaac aaaaagaaaa cctgaaggag catttggaag tcaatttgag gttttttttt     2040

ttgttttttt tttttttgta tgttggaacg tgccccagaa tgaggcagtt ggcaaacttc     2100

tcaggacaat gaatccttcc cgtttttctt tttatgccac acagtgcatt gttttttcta     2160

cctgcttgtc ttatttttag aataatttag aaaaacaaaa caaaggctgt ttttcctaat     2220

tttggcatga accccccctt gttccaaatg aagacggcat cacgaagcag ctccaaaagg     2280

aaaagcttgg gcggtgccca gcgtgcccgc tgcccatcga cgtctgtcct ggggacgtgg     2340

agggtggcag cgtccccgcc tgcaccagtg ccgtcctgct gatgtggtag gctagcaata     2400

ttttggttaa aatcatgttt gtgactgtaa ccatttgtat gaattatttt aaagaaataa     2460

aaatcctgga aagagccagc gtg                                             2483


<210>  298
<211>  4422
<212>  DNA
<213>  homo sapiens

<400>  298
gcggccgccg cgccgcgcac ccatggacgg cccggccatc atcacccagg tgaccaaccc       60

caaggaggac gagggccggt tgccgggcgc gggcgagaaa gcctcccagt gcaacgtcag      120

cttaaagaag cagaggagcc gcagcatcct tagctccttc ttctgctgct tccgtgatta      180

caatgtggag gcccctccac ccagcagccc cagtgtgctt ccgccactgg tggaggagaa      240

tggtgggctt cagaagccac cagctaagta ccttcttcca gaggtgacgg tgcttgacta      300

tggaaagaaa tgtgtggtca ttgatttaga tgaaacattg gtgcacagtt cgtttaagcc      360

tattagtaat gctgatttta ttgttccggt tgaaatcgat ggaactatac atcaggtgta      420

tgtgctgaag cggccacatg tggacgagtt cctccagagg atggggcagc tttttgaatg      480

tgtgctcttt actgccagct tggccaagta tgcagaccct gtggctgacc tcctagaccg      540

ctggggtgtg ttccgggccc ggctcttcag agaatcatgt gtttttcatc gtgggaacta      600

cgtgaaggac ctgagtcgcc ttgggcggga gctgagcaaa gtgatcattg ttgacaattc      660

ccctgcctca tacatcttcc atcctgagaa tgcagtgcct gtgcagtcct ggttcgatga      720

catgacggac acggagctgc tggacctcat ccccttcttt gagggcctga gccgggagga      780

cgacgtgtac agcatgctgc acagactctg caataggtag ccctggcctc tgcctgcctc      840

ccgcctgtgc actctggaac ctctggcctc aggggacctg cctgtcctca gctccctggg      900

agctgaaagt gaggatactc cgtgctccag gccacagggt gaatgtggcc atgcctacct      960

gttttgtttt tttaagaaca gaaacaacta ttttaaaaga actcttttaa gaaatttcat     1020

aaagggacat gcattttact gggtttgctt ttcttaaaac ataccaaaaa agaaaaaaat     1080

agaaaaaaaa aaaaaaaaag cttgatctct atcagacttc ctttcaactg tcctcccctc     1140

caagcagacc acctgtcccc ttctatccca gctcagagca gctgacccaa ctcagaatct     1200

ctttcctaca ggatgaagtg ccttttgaat gttattttaa gccgagagtt aatttttcta     1260

cacaacatat ttccagacat cttttagtct tttattgtct tagatactat aagaagatga     1320

acatgacaat tttctagaac ctggtagcgt gtgtgtgtgt ggcggggggt gctgagggag     1380

gggagtgagt cacaggagcc tgtcccccaa caggtgtgac tgctctgaca acctgtggca     1440

tgctgcaggg tcaggctcct gataggagga tttcatgact atgtcattgt ctccactcat     1500

ttttgaccca gtttggaatg tatctgcaat tgtgtggctc aacactttag gaaacaatag     1560

attattttat attattattt ctgatggtga caagtttgtc ttgaggtcac attttctcct     1620

tgaaaagtga catcctgtca cttctgctct cacactactg ccatacattt gtgttttttg     1680

ttgttattgt ttgggtagag cagttacaag aaaccctaaa acccttggat ataaaagaaa     1740

tctgtttatt gatttttaaa tctttccttt ccaaaagctg gatacacatg gagctgtttg     1800

ggaattttcc ttgctgctac cgcgctgcca ccaaatggaa ttgaccagcg gctgttacac     1860

tgttctttgc cactgtgcct atgctcagaa tatgctcact gctaagctac aaactcggac     1920

agggtcagaa acagaggtgt cccatcccat tgcagcctcc accacctgta accccttcct     1980

ggcattggcc actgaagggt acaaaggcaa aaggaccaca gcaccactta ggtgtagcat     2040

ggattttaaa ctgcagtcag tatcagatcc tgtttgataa ataagctgac tgttctctct     2100

tgagaacctg tggcctcaac cagccaccaa gctgatgtgg cccaagtcca tctcttggtc     2160

ttctcctttg aagcacagcc tatttctgag ccaagggttg gggaagcctg tctagatgtg     2220

ggactcattg ccccaaacca gggagaggaa gagctcccac agggagagcc caggctctct     2280

ttgcagcctt tcccagtttg gtgtttaagc agtgccatgt tccttgtttg acaacaagac     2340

agtctgtaaa gtattgctct taaaaacaat taaaaagaac cctttcatat tggcaccatt     2400

gccttagtcc tctgtgggtt ggtcttcagc cagcattctg gtgggagtga ctggcattaa     2460

caagactgga aatcgggggt caaagtaaaa tatctttgtt ttgctttcat tcacaaagta     2520

atgaagccag ctgccaatta catcctccca acagcacttt ggtctgtgga ctgctgtgtg     2580

aatattcaga agggaagtaa gtattcaggg ggtaaacagg tctcccagca ttctgagtgt     2640

tccaaaccag taatccacat gccaattcaa atagaacagc cccttgctag atattaccac     2700

agataatgac agttacatgg tagaactgcc catgccacaa atatttattt ggaaaagtag     2760

tcattaaatg aacccactgc cttaaatgtc ttgaatgttg cagtcaagtg tctgtcatgt     2820

gttgatatcc acacagaatt aggccctaat gagagcctta gaccctcaac catgccccct     2880

tcgttggcat cacagggcct tatttggaag agcgggcaaa gaggatggaa atcataaaat     2940

atttcatggg aatcgaacct agggatagtg ctccacttct gacgatggag tgaagacact     3000

tggcagactt gagccagaca cttcacctag tagttcctga aactgtgagc accactgcac     3060

taagccagtg cggagctgtt agggacgggc ccagctcctg caccacggac acagaatgtc     3120

tggagagggc cagcaggccc tctgagggtt ctggaatctg tgcaccttat ttgaccacac     3180

tccaaaattc tgtttttatt ttaacccttg aatctgcttt atgtacataa tcaaaatatc     3240

tatatctata tctatatcta tatctatata tttttaatca tctacatgta aatgaagcaa     3300

tagaattcta acataaggcc aagaaatgag acgaatgttt ggggtttatg ttttttaagg     3360

taaatacggg tattgttttt aattattacc atgtattaaa ttgtgggctt tgaaacctaa     3420

tgaaacctgt tagccacttc tctgtgccat atacttccca tgttaccaaa atacccccaa     3480

ctctttagcc aaaagagaac cctgacctcc tgagtttcca tgctcctttc tgtaccaggt     3540

ttaaatgtag tcttctggag aagtattttt gacattgagc tctgggacag gacaccttgg     3600

gtttgtggac tgcagcccac tatgatgtta ttacttctct ggccaggcct ccagtggaag     3660

tgcacaggca ctcccaatgt tgttaatgct ctgtcttcca tttgttctgg aatcctacgt     3720

gttggtctgt ggttccatgc attagctgtt tgtaaataat gcatttgcat actgaaaaag     3780

gaatgccacc tgccacagtt gatggtgagg aagctccttt gacgtggtgc aattttgatg     3840

agatgtctct ggggacacga ggatgcccta atgatgctga cttgtcatgg ttgcagcatt     3900

tgaacttttg gtgttaaaaa aaaaaacctg taagtctgta acctggcaac attttacaac     3960

cctgtatttt taaagatggc tttctaataa aaaatccaga accacacagc cctatggtca     4020

aacaatccta cgtttgtgcc tctgctttta aaggtgctgt gctggacagt tggcatgcca     4080

gggttcgaga agagtgaatg gcttgacgta cttgcagtta actgtgcaaa attggctggc     4140

tgcctctgtt cctactgtac tgtaactttg atcatgtctg ttcctgttcc attctcccag     4200

gagcttctct gcagactgac acaccctccc ccaccccggg tagtggagat gctggtgtct     4260

gggtagtcat ggatttctgc tggacatttg aatgtgataa acaatccagc attacttagg     4320

aaatgctaca tgcggaatgt gcacgtttcc aggggcgagt attgtcaatc aaaaggtttg     4380

caatgatttc cttcctgcca aaaataaaca tgtgaaactg ca                        4422


<210>  299
<211>  4455
<212>  DNA
<213>  homo sapiens

<400>  299
gcggccgccg cgccgcgcac ccatggacgg cccggccatc atcacccagg tgaccaaccc       60

caaggaggac gagggccggt tgccgggcgc gggcgagaaa gcctcccagt gcaacgtcag      120

cttaaagaag cagaggagcc gcagcatcct tagctccttc ttctgctgct tccgtgatta      180

caatgtggag gcccctccac ccagcagccc cagtgtgctt ccgccactgg tggaggagaa      240

tggtgggctt cagaagggtg accagaggca ggtcattccc ataccaagtc caccagctaa      300

gtaccttctt ccagaggtga cggtgcttga ctatggaaag aaatgtgtgg tcattgattt      360

agatgaaaca ttggtgcaca gttcgtttaa gcctattagt aatgctgatt ttattgttcc      420

ggttgaaatc gatggaacta tacatcaggt gtatgtgctg aagcggccac atgtggacga      480

gttcctccag aggatggggc agctttttga atgtgtgctc tttactgcca gcttggccaa      540

gtatgcagac cctgtggctg acctcctaga ccgctggggt gtgttccggg cccggctctt      600

cagagaatca tgtgtttttc atcgtgggaa ctacgtgaag gacctgagtc gccttgggcg      660

ggagctgagc aaagtgatca ttgttgacaa ttcccctgcc tcatacatct tccatcctga      720

gaatgcagtg cctgtgcagt cctggttcga tgacatgacg gacacggagc tgctggacct      780

catccccttc tttgagggcc tgagccggga ggacgacgtg tacagcatgc tgcacagact      840

ctgcaatagg tagccctggc ctctgcctgc ctcccgcctg tgcactctgg aacctctggc      900

ctcaggggac ctgcctgtcc tcagctccct gggagctgaa agtgaggata ctccgtgctc      960

caggccacag ggtgaatgtg gccatgccta cctgttttgt ttttttaaga acagaaacaa     1020

ctattttaaa agaactcttt taagaaattt cataaaggga catgcatttt actgggtttg     1080

cttttcttaa aacataccaa aaaagaaaaa aatagaaaaa aaaaaaaaaa aagcttgatc     1140

tctatcagac ttcctttcaa ctgtcctccc ctccaagcag accacctgtc cccttctatc     1200

ccagctcaga gcagctgacc caactcagaa tctctttcct acaggatgaa gtgccttttg     1260

aatgttattt taagccgaga gttaattttt ctacacaaca tatttccaga catcttttag     1320

tcttttattg tcttagatac tataagaaga tgaacatgac aattttctag aacctggtag     1380

cgtgtgtgtg tgtggcgggg ggtgctgagg gaggggagtg agtcacagga gcctgtcccc     1440

caacaggtgt gactgctctg acaacctgtg gcatgctgca gggtcaggct cctgatagga     1500

ggatttcatg actatgtcat tgtctccact catttttgac ccagtttgga atgtatctgc     1560

aattgtgtgg ctcaacactt taggaaacaa tagattattt tatattatta tttctgatgg     1620

tgacaagttt gtcttgaggt cacattttct ccttgaaaag tgacatcctg tcacttctgc     1680

tctcacacta ctgccataca tttgtgtttt ttgttgttat tgtttgggta gagcagttac     1740

aagaaaccct aaaacccttg gatataaaag aaatctgttt attgattttt aaatctttcc     1800

tttccaaaag ctggatacac atggagctgt ttgggaattt tccttgctgc taccgcgctg     1860

ccaccaaatg gaattgacca gcggctgtta cactgttctt tgccactgtg cctatgctca     1920

gaatatgctc actgctaagc tacaaactcg gacagggtca gaaacagagg tgtcccatcc     1980

cattgcagcc tccaccacct gtaacccctt cctggcattg gccactgaag ggtacaaagg     2040

caaaaggacc acagcaccac ttaggtgtag catggatttt aaactgcagt cagtatcaga     2100

tcctgtttga taaataagct gactgttctc tcttgagaac ctgtggcctc aaccagccac     2160

caagctgatg tggcccaagt ccatctcttg gtcttctcct ttgaagcaca gcctatttct     2220

gagccaaggg ttggggaagc ctgtctagat gtgggactca ttgccccaaa ccagggagag     2280

gaagagctcc cacagggaga gcccaggctc tctttgcagc ctttcccagt ttggtgttta     2340

agcagtgcca tgttccttgt ttgacaacaa gacagtctgt aaagtattgc tcttaaaaac     2400

aattaaaaag aaccctttca tattggcacc attgccttag tcctctgtgg gttggtcttc     2460

agccagcatt ctggtgggag tgactggcat taacaagact ggaaatcggg ggtcaaagta     2520

aaatatcttt gttttgcttt cattcacaaa gtaatgaagc cagctgccaa ttacatcctc     2580

ccaacagcac tttggtctgt ggactgctgt gtgaatattc agaagggaag taagtattca     2640

gggggtaaac aggtctccca gcattctgag tgttccaaac cagtaatcca catgccaatt     2700

caaatagaac agccccttgc tagatattac cacagataat gacagttaca tggtagaact     2760

gcccatgcca caaatattta tttggaaaag tagtcattaa atgaacccac tgccttaaat     2820

gtcttgaatg ttgcagtcaa gtgtctgtca tgtgttgata tccacacaga attaggccct     2880

aatgagagcc ttagaccctc aaccatgccc ccttcgttgg catcacaggg ccttatttgg     2940

aagagcgggc aaagaggatg gaaatcataa aatatttcat gggaatcgaa cctagggata     3000

gtgctccact tctgacgatg gagtgaagac acttggcaga cttgagccag acacttcacc     3060

tagtagttcc tgaaactgtg agcaccactg cactaagcca gtgcggagct gttagggacg     3120

ggcccagctc ctgcaccacg gacacagaat gtctggagag ggccagcagg ccctctgagg     3180

gttctggaat ctgtgcacct tatttgacca cactccaaaa ttctgttttt attttaaccc     3240

ttgaatctgc tttatgtaca taatcaaaat atctatatct atatctatat ctatatctat     3300

atatttttaa tcatctacat gtaaatgaag caatagaatt ctaacataag gccaagaaat     3360

gagacgaatg tttggggttt atgtttttta aggtaaatac gggtattgtt tttaattatt     3420

accatgtatt aaattgtggg ctttgaaacc taatgaaacc tgttagccac ttctctgtgc     3480

catatacttc ccatgttacc aaaatacccc caactcttta gccaaaagag aaccctgacc     3540

tcctgagttt ccatgctcct ttctgtacca ggtttaaatg tagtcttctg gagaagtatt     3600

tttgacattg agctctggga caggacacct tgggtttgtg gactgcagcc cactatgatg     3660

ttattacttc tctggccagg cctccagtgg aagtgcacag gcactcccaa tgttgttaat     3720

gctctgtctt ccatttgttc tggaatccta cgtgttggtc tgtggttcca tgcattagct     3780

gtttgtaaat aatgcatttg catactgaaa aaggaatgcc acctgccaca gttgatggtg     3840

aggaagctcc tttgacgtgg tgcaattttg atgagatgtc tctggggaca cgaggatgcc     3900

ctaatgatgc tgacttgtca tggttgcagc atttgaactt ttggtgttaa aaaaaaaaac     3960

ctgtaagtct gtaacctggc aacattttac aaccctgtat ttttaaagat ggctttctaa     4020

taaaaaatcc agaaccacac agccctatgg tcaaacaatc ctacgtttgt gcctctgctt     4080

ttaaaggtgc tgtgctggac agttggcatg ccagggttcg agaagagtga atggcttgac     4140

gtacttgcag ttaactgtgc aaaattggct ggctgcctct gttcctactg tactgtaact     4200

ttgatcatgt ctgttcctgt tccattctcc caggagcttc tctgcagact gacacaccct     4260

cccccacccc gggtagtgga gatgctggtg tctgggtagt catggatttc tgctggacat     4320

ttgaatgtga taaacaatcc agcattactt aggaaatgct acatgcggaa tgtgcacgtt     4380

tccaggggcg agtattgtca atcaaaaggt ttgcaatgat ttccttcctg ccaaaaataa     4440

acatgtgaaa ctgca                                                      4455


<210>  300
<211>  1678
<212>  DNA
<213>  homo sapiens

<400>  300
ggggcgtgaa gggagccggg atcagccagg ggccagcatg agccggaggg agggaagtct       60

ggacccccag actgattcct cagtctcact tcttccccac ttggaggcca agatccgtca      120

gacacacagc cttgcgcacc tcctcaccaa atacgctgag cagctgctcc aggaatatgt      180

gcagctccag ggagacccct tcgggctgcc cagcttctcg ccgccgcggc tgccggtggc      240

cggcctgagc gccccggctc cgagccacgc ggggctgcca gtgcacgagc ggctgcggct      300

ggacgcggcg gcgctggccg cgctgccccc gctgctggac gcagtgtgtc gccgccaggc      360

cgagctgaac ccgcgcgcgc cgcgcctgct gcgccgcctg gaggacgcgg cgcgccaggc      420

ccgggccctg ggcgccgccg tggaggcctt gctggccgcg ctgggcgccg ccaaccgcgg      480

gccccgggcc gagccccccg ccgccaccgc ctcagccgcc tccgccaccg gggtcttccc      540

cgccaaggtg ctggggctcc gcgtttgcgg cctctaccgc gagtggctga gccgcaccga      600

gggcgacctg ggccagctgc tgcccggggg ctcggcctga gcgccgcggg gcagctcgcc      660

ccgcctcctc ccgctgggtt ccgtctctcc ttccgcttct ttgtctttct ctgccgctgt      720

cggtgtctgt ctgtctgctc ttagctgtct ccattgcctc ggccttcttt gctttttgtg      780

ggggagaggg gaggggacgg gcagggtctc tgtcgcccag gctggggtgc agtggcgcga      840

tcccagcact gcagcctcaa cctcctgggc tcaagccatc cttccgcctc agcttcccca      900

gcagctggga ctacaggcac gcgccaccac agccggctaa ttttttattt aattttttgt      960

agagacgagg tttcgccatg ttgcccaggc tggtcttgaa ctccggggct caagcgatcc     1020

tcccgcttca gcctccctaa gtgctgggat tgcaggcgtg agccactttc ccagcctctc     1080

tttgctttgc ctgccccgtt ctcttaactc ttggaccctc ctcgtctgca tggtaactcc     1140

gtctgagtct accattttct tgctctccct ccttccttgg gcctgcctca gttccctttg     1200

gcctccccct ttacccagct cttggggtgt ctctgttttt tccatcccca cttcctgcct     1260

tctcgtggcc ctgtgtgagc acatgtgtac atctcagcct tatctcaagg aggtgacacc     1320

ttctctcctt gtccccatct ggccgtctct ctgtgcttcc ctggccaggg gcgtgcctgc     1380

tggtcctatg gggggaaggc tactctgcat ctcagccacc ttcctcaggc tcactccacc     1440

tacatcccca gtctgccaca ccccatccct ttgggcctca gccctgtccc tttgatgtcc     1500

tcctttcctt cagcccctct gccctgtccc tgcacacctc cactgcctcc cagcagatct     1560

gtggagacaa aacaagcaac accttaaaag agttttattt ctgaaaataa attaattttt     1620

tgtaaataaa atgtttaaaa ataaaaaaga aactaaagtt aaaaaaaaaa aaaaaaaa       1678


<210>  301
<211>  3720
<212>  DNA
<213>  homo sapiens

<400>  301
aggatacagc ggcttctgcg cgacttataa gagctccttg tgcggcgcca ttttaagcct       60

ctcggtctgt ggcagcagcg ttggcccggc cccgggagcg gagagcgagg ggaggcggag      120

acggaggaag gtctgaggag cagcttcagt ccccgccgag ccgccaccgc aggtcgagga      180

cggtcggact cccgcggcgg gaggagcctg ttcccctgag ggtatttgaa gtataccata      240

caactgtttt gaaaatccag cgtggacaat ggctactcaa gctgatttga tggagttgga      300

catggccatg gaaccagaca gaaaagcggc tgttagtcac tggcagcaac agtcttacct      360

ggactctgga atccattctg gtgccactac cacagctcct tctctgagtg gtaaaggcaa      420

tcctgaggaa gaggatgtgg atacctccca agtcctgtat gagtgggaac agggattttc      480

tcagtccttc actcaagaac aagtagctga tattgatgga cagtatgcaa tgactcgagc      540

tcagagggta cgagctgcta tgttccctga gacattagat gagggcatgc agatcccatc      600

tacacagttt gatgctgctc atcccactaa tgtccagcgt ttggctgaac catcacagat      660

gctgaaacat gcagttgtaa acttgattaa ctatcaagat gatgcagaac ttgccacacg      720

tgcaatccct gaactgacaa aactgctaaa tgacgaggac caggtggtgg ttaataaggc      780

tgcagttatg gtccatcagc tttctaaaaa ggaagcttcc agacacgcta tcatgcgttc      840

tcctcagatg gtgtctgcta ttgtacgtac catgcagaat acaaatgatg tagaaacagc      900

tcgttgtacc gctgggacct tgcataacct ttcccatcat cgtgagggct tactggccat      960

ctttaagtct ggaggcattc ctgccctggt gaaaatgctt ggttcaccag tggattctgt     1020

gttgttttat gccattacaa ctctccacaa ccttttatta catcaagaag gagctaaaat     1080

ggcagtgcgt ttagctggtg ggctgcagaa aatggttgcc ttgctcaaca aaacaaatgt     1140

taaattcttg gctattacga cagactgcct tcaaatttta gcttatggca accaagaaag     1200

caagctcatc atactggcta gtggtggacc ccaagcttta gtaaatataa tgaggaccta     1260

tacttacgaa aaactactgt ggaccacaag cagagtgctg aaggtgctat ctgtctgctc     1320

tagtaataag ccggctattg tagaagctgg tggaatgcaa gctttaggac ttcacctgac     1380

agatccaagt caacgtcttg ttcagaactg tctttggact ctcaggaatc tttcagatgc     1440

tgcaactaaa caggaaggga tggaaggtct ccttgggact cttgttcagc ttctgggttc     1500

agatgatata aatgtggtca cctgtgcagc tggaattctt tctaacctca cttgcaataa     1560

ttataagaac aagatgatgg tctgccaagt gggtggtata gaggctcttg tgcgtactgt     1620

ccttcgggct ggtgacaggg aagacatcac tgagcctgcc atctgtgctc ttcgtcatct     1680

gaccagccga caccaagaag cagagatggc ccagaatgca gttcgccttc actatggact     1740

accagttgtg gttaagctct tacacccacc atcccactgg cctctgataa aggctactgt     1800

tggattgatt cgaaatcttg ccctttgtcc cgcaaatcat gcacctttgc gtgagcaggg     1860

tgccattcca cgactagttc agttgcttgt tcgtgcacat caggataccc agcgccgtac     1920

gtccatgggt gggacacagc agcaatttgt ggagggggtc cgcatggaag aaatagttga     1980

aggttgtacc ggagcccttc acatcctagc tcgggatgtt cacaaccgaa ttgttatcag     2040

aggactaaat accattccat tgtttgtgca gctgctttat tctcccattg aaaacatcca     2100

aagagtagct gcaggggtcc tctgtgaact tgctcaggac aaggaagctg cagaagctat     2160

tgaagctgag ggagccacag ctcctctgac agagttactt cactctagga atgaaggtgt     2220

ggcgacatat gcagctgctg ttttgttccg aatgtctgag gacaagccac aagattacaa     2280

gaaacggctt tcagttgagc tgaccagctc tctcttcaga acagagccaa tggcttggaa     2340

tgagactgct gatcttggac ttgatattgg tgcccaggga gaaccccttg gatatcgcca     2400

ggatgatcct agctatcgtt cttttcactc tggtggatat ggccaggatg ccttgggtat     2460

ggaccccatg atggaacatg agatgggtgg ccaccaccct ggtgctgact atccagttga     2520

tgggctgcca gatctggggc atgcccagga cctcatggat gggctgcctc caggtgacag     2580

caatcagctg gcctggtttg atactgacct gtaaatcatc ctttaggtaa gaagttttaa     2640

aaagccagtt tgggtaaaat acttttactc tgcctacaga acttcagaaa gacttggttg     2700

gtagggtggg agtggtttag gctatttgta aatctgccac aaaaacaggt atatactttg     2760

aaaggagatg tcttggaaca ttggaatgtt ctcagatttc tggttgttat gtgatcatgt     2820

gtggaagtta ttaactttaa tgttttttgc cacagctttt gcaacttaat actcaaatga     2880

gtaacatttg ctgttttaaa cattaatagc agcctttctc tctttataca gctgtattgt     2940

ctgaacttgc attgtgattg gcctgtagag ttgctgagag ggctcgaggg gtgggctggt     3000

atctcagaaa gtgcctgaca cactaaccaa gctgagtttc ctatgggaac aattgaagta     3060

aactttttgt tctggtcctt tttggtcgag gagtaacaat acaaatggat tttgggagtg     3120

actcaagaag tgaagaatgc acaagaatgg atcacaagat ggaatttatc aaaccctagc     3180

cttgcttgtt aaattttttt tttttttttt ttaagaatat ctgtaatggt actgactttg     3240

cttgctttga agtagctctt tttttttttt tttttttttt tttgcagtaa ctgtttttta     3300

agtctctcgt agtgttaagt tatagtgaat actgctacag caatttctaa tttttaagaa     3360

ttgagtaatg gtgtagaaca ctaattcata atcactctaa ttaattgtaa tctgaataaa     3420

gtgtaacaat tgtgtagcct ttttgtataa aatagacaaa tagaaaatgg tccaattagt     3480

ttccttttta atatgcttaa aataagcagg tggatctatt tcatgttttt gatcaaaaac     3540

tatttgggat atgtatgggt agggtaaatc agtaagaggt gttatttgga accttgtttt     3600

ggacagttta ccagttgcct tttatcccaa agttgttgta acctgctgtg atacgatgct     3660

tcaagagaaa atgcggttat aaaaaatggt tcagaattaa acttttaatt cattcgattg     3720


<210>  302
<211>  3415
<212>  DNA
<213>  homo sapiens

<400>  302
aggatacagc ggcttctgcg cgacttataa gagctccttg tgcggcgcca ttttaagcct       60

ctcggtctgt ggcagcagcg ttggcccggc cccgggagcg gagagcgagg ggaggcggag      120

acggaggaag gtctgaggag cagcttcagt ccccgccgag ccgccaccgc aggtcgagga      180

cggtcggact cccgcggcgg gaggagcctg ttcccctgag ggtatttgaa gtataccata      240

caactgtttt gaaaatccag cgtggacaat ggctactcaa gctgatttga tggagttgga      300

catggccatg gaaccagaca gaaaagcggc tgttagtcac tggcagcaac agtcttacct      360

ggactctgga atccattctg gtgccactac cacagctcct tctctgagtg gtaaaggcaa      420

tcctgaggaa gaggatgtgg atacctccca agtcctgtat gagtgggaac agggattttc      480

tcagtccttc actcaagaac aagtagctga tattgatgga cagtatgcaa tgactcgagc      540

tcagagggta cgagctgcta tgttccctga gacattagat gagggcatgc agatcccatc      600

tacacagttt gatgctgctc atcccactaa tgtccagcgt ttggctgaac catcacagat      660

gctgaaacat gcagttgtaa acttgattaa ctatcaagat gatgcagaac ttgccacacg      720

tgcaatccct gaactgacaa aactgctaaa tgacgaggac caggtggtgg ttaataaggc      780

tgcagttatg gtccatcagc tttctaaaaa ggaagcttcc agacacgcta tcatgcgttc      840

tcctcagatg gtgtctgcta ttgtacgtac catgcagaat acaaatgatg tagaaacagc      900

tcgttgtacc gctgggacct tgcataacct ttcccatcat cgtgagggct tactggccat      960

ctttaagtct ggaggcattc ctgccctggt gaaaatgctt ggttcaccag tggattctgt     1020

gttgttttat gccattacaa ctctccacaa ccttttatta catcaagaag gagctaaaat     1080

ggcagtgcgt ttagctggtg ggctgcagaa aatggttgcc ttgctcaaca aaacaaatgt     1140

taaattcttg gctattacga cagactgcct tcaaatttta gcttatggca accaagaaag     1200

caagctcatc atactggcta gtggtggacc ccaagcttta gtaaatataa tgaggaccta     1260

tacttacgaa aaactactgt ggaccacaag cagagtgctg aaggtgctat ctgtctgctc     1320

tagtaataag ccggctattg tagaagctgg tggaatgcaa gctttaggac ttcacctgac     1380

agatccaagt caacgtcttg ttcagaactg tctttggact ctcaggaatc tttcagatgc     1440

tgcaactaaa caggaaggga tggaaggtct ccttgggact cttgttcagc ttctgggttc     1500

agatgatata aatgtggtca cctgtgcagc tggaattctt tctaacctca cttgcaataa     1560

ttataagaac aagatgatgg tctgccaagt gggtggtata gaggctcttg tgcgtactgt     1620

ccttcgggct ggtgacaggg aagacatcac tgagcctgcc atctgtgctc ttcgtcatct     1680

gaccagccga caccaagaag cagagatggc ccagaatgca gttcgccttc actatggact     1740

accagttgtg gttaagctct tacacccacc atcccactgg cctctgataa aggctactgt     1800

tggattgatt cgaaatcttg ccctttgtcc cgcaaatcat gcacctttgc gtgagcaggg     1860

tgccattcca cgactagttc agttgcttgt tcgtgcacat caggataccc agcgccgtac     1920

gtccatgggt gggacacagc agcaatttgt ggagggggtc cgcatggaag aaatagttga     1980

aggttgtacc ggagcccttc acatcctagc tcgggatgtt cacaaccgaa ttgttatcag     2040

aggactaaat accattccat tgtttgtgca gctgctttat tctcccattg aaaacatcca     2100

aagagtagct gcaggggtcc tctgtgaact tgctcaggac aaggaagctg cagaagctat     2160

tgaagctgag ggagccacag ctcctctgac agagttactt cactctagga atgaaggtgt     2220

ggcgacatat gcagctgctg ttttgttccg aatgtctgag gacaagccac aagattacaa     2280

gaaacggctt tcagttgagc tgaccagctc tctcttcaga acagagccaa tggcttggaa     2340

tgagactgct gatcttggac ttgatattgg tgcccaggga gaaccccttg gatatcgcca     2400

ggatgatcct agctatcgtt cttttcactc tggtggatat ggccaggatg ccttgggtat     2460

ggaccccatg atggaacatg agatgggtgg ccaccaccct ggtgctgact atccagttga     2520

tgggctgcca gatctggggc atgcccagga cctcatggat gggctgcctc caggtgacag     2580

caatcagctg gcctggtttg atactgacct gtaaatcatc ctttagctgt attgtctgaa     2640

cttgcattgt gattggcctg tagagttgct gagagggctc gaggggtggg ctggtatctc     2700

agaaagtgcc tgacacacta accaagctga gtttcctatg ggaacaattg aagtaaactt     2760

tttgttctgg tcctttttgg tcgaggagta acaatacaaa tggattttgg gagtgactca     2820

agaagtgaag aatgcacaag aatggatcac aagatggaat ttatcaaacc ctagccttgc     2880

ttgttaaatt tttttttttt tttttttaag aatatctgta atggtactga ctttgcttgc     2940

tttgaagtag ctcttttttt tttttttttt ttttttttgc agtaactgtt ttttaagtct     3000

ctcgtagtgt taagttatag tgaatactgc tacagcaatt tctaattttt aagaattgag     3060

taatggtgta gaacactaat tcataatcac tctaattaat tgtaatctga ataaagtgta     3120

acaattgtgt agcctttttg tataaaatag acaaatagaa aatggtccaa ttagtttcct     3180

ttttaatatg cttaaaataa gcaggtggat ctatttcatg tttttgatca aaaactattt     3240

gggatatgta tgggtagggt aaatcagtaa gaggtgttat ttggaacctt gttttggaca     3300

gtttaccagt tgccttttat cccaaagttg ttgtaacctg ctgtgatacg atgcttcaag     3360

agaaaatgcg gttataaaaa atggttcaga attaaacttt taattcattc gattg          3415


<210>  303
<211>  8352
<212>  DNA
<213>  homo sapiens

<400>  303
atttagaggc ggcgccaggg cggccgcgga gaaacgtgac acaccagccc tctcggaggg       60

gtttcggacc gaagggaaga agctgcgccg tgtcgtccgt ctccctgcgc gccgcgggca      120

cttctcctgg gctctccccg aactctcccg cgacctctgc gcgccctcag gccgccttcc      180

ccgccctggg ctcgggacaa cttctggggt ggggtgcaaa gaaagtttgc ggctcctgcc      240

gccggcctct ccgcctcttg gcctaggagg ctcgccgccc gcgcccgctc gttcggcctt      300

gcccgggacc gcgtcctgcc ccgagaccgc caccatgaac aagctttaca tcggcaacct      360

caacgagagc gtgacccccg cggacttgga gaaagtgttt gcggagcaca agatctccta      420

cagcggccag ttcttggtca aatccggcta cgccttcgtg gactgcccgg acgagcactg      480

ggcgatgaag gccatcgaaa ctttctccgg gaaagtagaa ttacaaggaa aacgcttaga      540

gattgaacat tcggtgccca aaaaacaaag gagccggaaa attcaaatcc gaaatattcc      600

accccagctc cgatgggaag tactggacag cctgctggct cagtatggta cagtagagaa      660

ctgtgagcaa gtgaacaccg agagtgagac ggcagtggtg aatgtcacct attccaaccg      720

ggagcagacc aggcaggctg acgaggttcc cctgaagatc ctggcccata ataactttgt      780

agggcgtctc attggcaagg aaggacggaa cctgaagaag gtagagcaag ataccgagac      840

aaaaatcacc atctcctcgt tgcaagacct taccctttac aaccctgaga ggaccatcac      900

tgtgaagggg gccatcgaga attgttgcag ggccgagcag gaaataatga agaaagttcg      960

ggaggcctat gagaatgatg tggctgccat gagcctgcag tctcacctga tccctggcct     1020

gaacctggct gctgtaggtc ttttcccagc ttcatccagc gcagtcccgc cgcctcccag     1080

cagcgttact ggggctgctc cctatagctc ctttatgcag gctcccgagc aggagatggt     1140

gcaggtgttt atccccgccc aggcagtggg cgccatcatc ggcaagaagg ggcagcacat     1200

caaacagctc tcccggtttg ccagcgcctc catcaagatt gcaccacccg aaacacctga     1260

ctccaaagtt cgtatggtta tcatcactgg accgccagag gcccaattca aggctcaggg     1320

aagaatctat ggcaaactca aggaggagaa cttctttggt cccaaggagg aagtgaagct     1380

ggagacccac atacgtgtgc cagcatcagc agctggccgg gtcattggca aaggtggaaa     1440

aacggtgaac gagttgcaga atttgacggc agctgaggtg gtagtaccaa gagaccagac     1500

ccctgatgag aacgaccagg tcatcgtgaa aatcatcgga catttctatg ccagtcagat     1560

ggctcaacgg aagatccgag acatcctggc ccaggttaag cagcagcatc agaagggaca     1620

gagtaaccag gcccaggcac ggaggaagtg accagcccct ccctgtccct tcgagtccag     1680

gacaacaacg ggcagaaatc gagagtgtgc tctccccggc aggcctgaga atgagtggga     1740

atccgggaca cctgggccgg gctgtagatc aggtttgccc acttgattga gaaagatgtt     1800

ccagtgagga accctgatct ctcagcccca aacacccacc caattggccc aacactgtct     1860

gcccctcggg gtgtcagaaa ttctagcgca aggcactttt aaacgtggat tgtttaaaga     1920

agctctccag gccccaccaa gagggtggat cacacctcag tgggaagaaa aataaaattt     1980

ccttcaggtt ttaaaaacat gcagagaggt gttttaatca gccttaaagg atggttcatt     2040

tcttgacctt aatgtttttc caatcttctt ccccctactt gggtaattga ttaaaatacc     2100

tccatttacg gcctctttct atatttacac taattttttt atctttattg ctaccagaaa     2160

aaaatgcgaa cgaatgcatt gctttgctta cagtattgac tcaagggaaa agaactgtca     2220

gtatctgtag attaattcca atcactccct aaccaatagg tacaatacgg aatgaagaag     2280

aggggaaaat ggggagaaag atggttaaaa tacataataa tccacgttta aaaggagcgc     2340

acttgtggct gatctatgcc agatcaccat cttcaaattg gcacaactga aatttcccca     2400

ctctgttggg gcttccccac cacattcatg tccctctccc gtgtaggttt cacattatgt     2460

ccaggtgcac ataggtggta ttgaatgctc agcagggtag gggctgacca ctgtccctga     2520

ttcccatcgt tctcaggcgg attttatatt tttttaaagt ctattttaat gattggatat     2580

gagcactggg aaggggacgc taactcccct tgataaagtc tcggttccat ggaggacttg     2640

agtggcccca aaggctgcca cggtgccctc accccagccc atgtgctccc ataagggctg     2700

gttcctagag gcaggggttg tggggcactc ccagccacgg cactgttacc ttggtggtgg     2760

gacttggaac ccaaccctga gctcccgata aagctaaagt ccatcatctg gcaaattcag     2820

taaattggag agtacttgct tctgtttgta tctgagagga atttttaact gacggcttct     2880

gtctccatga atcattatca gcatgatgaa aggtgtgtct aaaaaacaat tcagaatacc     2940

agcagcattg tacagcaagg ggtaaataag cttaatttat taatttacca ggcttaatta     3000

agatcccatg gagtgtttag cccttgtggg agacagaagc catcagttaa atgaggttag     3060

gcctctcctc ctaatatact gattgacaat gcatattagc caggtaatgc actttagcta     3120

ccctggacaa tgctatcaag tgtgctggga agggaggaag gcctctctac atatggaaaa     3180

gcccatgcgt ggagttcccc tcctttcaac attgcaacaa cagtaacaac aagacaaccg     3240

caacatgtgg gcgtagtcag gcaatgctgt gtgcgaagta aactacctca aggtatgaag     3300

ttacctcagc aattattttc ctttttgttc cccccaaccc cattaaaaaa attttttttt     3360

gatttttgtt tttttgcagc ttgctgatat tttatataaa aaagaaaagc aaagcaaaag     3420

agaagctgat agtcttgaat attttatttt tttaatgaaa agaaaaaaca agaaagttat     3480

gtttcataat ttcttacaac atgagccagt aaccctttag gaactctcta tggagaacag     3540

gcctggtggg aaaggctttg ggggctgccc ccttaggagg aggctagtgc taagagggaa     3600

ggcccaggtt tgagagagcc cagaggggca gagcccagag ccttgtttgg ccctgatctc     3660

tgacttctag agccccagct gctggcggct gctggaatat cctacctgat aggattaaaa     3720

ggcctagtgg agctgggggc tctcagtggt taaacaatgc ccaacaacca accagctggc     3780

ccttggtctc ctctctttcc tcctttggtt aaagagcatc tcagccagct tttcccacca     3840

gtggtgctgt tgagatattt taaaatattg cctccgtttt atcgaggaga gaaataataa     3900

ctaaaaaata taccctttaa aaaaacctat atttctctgt ctaaaaatat gggagctgag     3960

attccgttcg tggaaaaaag acaaggccac cctctcgccc tcagagaggt ccacctggtt     4020

tgtcattgca atgcttttca tttttttttt ttgttattgt ttcatttcag ttccgtcttg     4080

ctattcttcc taatctatat ccatagatct aaggggcaaa cagatactag ttaactgccc     4140

ccacctctgt ctccctgtct tctttagatc ggtctgattg attttaaaag tggacccaaa     4200

cttagggaat tcttgattta gggtggctgg tggcaaggag gggcagggga tatggggacg     4260

tgactgggac aggttcctgc cttatcattt tctccctagg acattccctt gtagccccca     4320

gaattgtctg gcccaaattg aatagaagca gaaaaacatt tagggataac atcaggccag     4380

tagaattaag cctctccacc tgtcccaacc ataaaaaggg tctcccagct ttccatctct     4440

ggctctatat gctttatccc aaaacaaagc agataacgtt cagacgtcgg ccatttagta     4500

atttaaagcg aatttccagc agcaagcatg ctttgatatc tggttcagac tatcatcagg     4560

aagaaaaaaa aatcccacag tacctgaaat gtgattgttg cagtgttcag tttccttggg     4620

ggcctgctcc cttcacacct tgagcccaag tccttttccg ttggctgatt cagctcccag     4680

aagagacgag gaagtgtgtg gcaagggact ggaaaacttc acttgcttgg attaggcaag     4740

gctccactca ttgttgatat ttgcccagca ggaaaatcat gtaagttata ccaccagaaa     4800

gcaaaaggag catggtttgg tggttaaggt ttagtgggat gaaggacctg tcttggtggg     4860

ccgggccctc ttgtgccccg taggctaggt cttagggcaa ctccttgccc tcctgctcag     4920

cacctccatt tccccatcct tggtgagata acaagctatc gcgaaaagca cttgggagat     4980

ttggatgatt tgagaagagt gacttaaaaa aaatgcttct gtgctctaag atatatatgt     5040

gtgtgtgtgt gctacatata tatttttaag aaaggaccat ctctttagga tatattttta     5100

aattctttga aacacataac caaaatggtt tgattcactg actgactttg aagctgcatc     5160

tgccagttac accccaaatg gctttaatcc cctctcgggt ctggttgcct tttgcagttt     5220

gggttgtgga ctcagctcct gtgaggggtc tggttaggag agagccattt ttaaggacag     5280

ggagttttat agcccttttc tactttcctc ccctcctccc agtccttatc aatctttttt     5340

cctttttcct gaccccctcc ttctggaggc agttgggagc tatccttgtt tatgcctcac     5400

tattggcaga aaagacccca tttaaaaccc agagaacact ggagggggat gctctagttg     5460

gttctgtgtc cattttcctc tgtgccaaag acagacagac agaggctgag agaggctgtt     5520

cctgaatcaa agcaatagcc agctttcgac acatacctgg ctgtctgagg aggaaggcct     5580

cctggaaact gggagctaag ggcgaggccc ttcccttcag aggctcctgg gggattaggg     5640

tgtggtgttt gccaagccaa ggggtaggga gccgagaaat tggtctgtcg gctcctggtt     5700

gcactttggg gaaggagagg aagtttgggg ctccaggtag ctccctgttg tgggactgct     5760

ctgtcccctg cccctactgc agagatagca ctgccgagtt cccttcaggc ctggcagacg     5820

ggcagtgagg aggggcctca gttagctctc aagggtgcct tcccctcctc ccaacccaga     5880

cataccctct gccaaactgg gaaccagcag tgctagtaac tacctcacag agccccagag     5940

ggcctgcttg agccttcttg ctccacagga gaagctggtg cctctaggca accccttcct     6000

cccacctctc atcaggggtg ggggttctcc tttctttccc ctgaagtgtt tatggggaga     6060

tcctagtggc tttgccattc aaaccactcg actgtttgcc tgtttcttga aaaccagtag     6120

aagggaaaca gcacagcctg tcacagtaat tgcaggaaga ttgaagaaaa atcctcatca     6180

atgccagggg acataaaagc catttccctt ccaaatactc gacaatttag atgcagaaca     6240

tttctctgta ttcagactta gagtaacacc agctgaaaac tgcagtttct ttcctttgga     6300

tacataaggc ttctctatcg gggtacggga cagggaggag gcctcatgtc tgaaggggga     6360

tttaggggcg agagccccag ccctgaccct cggtcctgtg caccgctttg gggcacagtc     6420

tgatggcgcc tttgctggcg ccttagtatg gttgactccg gatggacaaa agaaaaaaaa     6480

ttttttttct tgaatgaaat agcaggaagc tcctcgggag catgtgtttt gattaaccgc     6540

aggtgatgga tgctacgagt ataaatggat taactacctc aatccttaca gtaagattgg     6600

aactaagggc agggactcat gcataagggt atgaatccca gccaggacaa gtgagttgag     6660

gcttgtgcca caaaaggttt gtccttgggg aacaggcagg cctgccagga tcccccccat     6720

atcgattggg ctgggagggc tggccatgag gtccccactt tctgctttcc ttgcccatgt     6780

gtcacccctt tggcctccag cttgtccctc tctcactttc tatagctttg ttggaccaga     6840

tggtgaggaa aggaatggcc tcttcccttc tagagggggc tggctggagt gagacctggg     6900

gcttggcctg gaacccacca cacagcccca aagtcaggaa gcctggggaa accagagctg     6960

agacctcttc aacagggttt ctttgagatc ctacacctcc attgggccct ttttcagtct     7020

tcaatggggg cccagttggc tctagaagga gaagaggtga agcaggatcc tttgccctgg     7080

gggagtctga gggcgcggtc cttggactca ttcaggccgt ctttgtagtt gggggagttc     7140

cactgggcga tcccagcccc tccccaccca ccctctaatg gacctcctca tagaagcccc     7200

atttcacttt tgttttatct acctcttagc aaaacaatag ataaattagg tagtggcagc     7260

tccacttgct taggttaggg ggggaaaaag atttcttttt ccaaaggaaa aaaatattac     7320

cttgagaata ctttccaaaa aataaaatta aaaaaaaaaa aaccaaaaaa aaaaattttt     7380

ttttaaaagg gagacatttt ccagtgacca ctggattgtt ttaatttccc aagctttttt     7440

ttcccccata aataagtttc actctttggc gattttcttc acttgtttaa gataacgtgc     7500

tagctattcc aacaggtaac agctttcaca gtctgcccct ggcctgtctc accccatccc     7560

ccaccctatt cctgccagtg agtccttcct gtgcttctct cccttctccc ctcccagcca     7620

gctgacttca gtcacccctg tcccccctcc cctgccaata agctccccca ggaataaagg     7680

ctttgttttg gggatgctta aatcttgact ggcacttccc ggctgtgggg gctggggagc     7740

cacttgtaac atttctgtgc agattttatg ttagccactg ctatgtaaaa gcacgttcaa     7800

aatgaatttc agcagattat gtgttaccat aatgaataaa cgtcctctat caccatttgg     7860

agtctccctt ttctccagga tcttgatcct ggtccccaaa accagagtga atcaaaagag     7920

cttcctcccc tgaggcaaag tggatttgta agcagttctg aaacatcact tactcagaag     7980

agggaacgat gtattttgat gagtgcaaat tgggaagagc tggaggccta ctgcttggga     8040

cagttttttt tttttttttt tttttaaata tgagtgctag cttattctgt aattgcggca     8100

actttgaaaa ttgtatttta ctggaaatct gccagccatc accacccgat tttgattgta     8160

tccttcctcc catcctttaa tctgttcatt gctttggggg aggtggggca gctggctcac     8220

acgttggagt ttgttctttg atggatgaac gaacactcca gttttctttc ccgtgaaggt     8280

tgtttcagcc acaaaccact tcattttgct gtttcaattt caaaataaaa ggaaacttat     8340

attgaaagac aa                                                         8352


<210>  304
<211>  8769
<212>  DNA
<213>  homo sapiens

<400>  304
atttagaggc ggcgccaggg cggccgcgga gaaacgtgac acaccagccc tctcggaggg       60

gtttcggacc gaagggaaga agctgcgccg tgtcgtccgt ctccctgcgc gccgcgggca      120

cttctcctgg gctctccccg aactctcccg cgacctctgc gcgccctcag gccgccttcc      180

ccgccctggg ctcgggacaa cttctggggt ggggtgcaaa gaaagtttgc ggctcctgcc      240

gccggcctct ccgcctcttg gcctaggagg ctcgccgccc gcgcccgctc gttcggcctt      300

gcccgggacc gcgtcctgcc ccgagaccgc caccatgaac aagctttaca tcggcaacct      360

caacgagagc gtgacccccg cggacttgga gaaagtgttt gcggagcaca agatctccta      420

cagcggccag ttcttggtca aatccggcta cgccttcgtg gactgcccgg acgagcactg      480

ggcgatgaag gccatcgaaa ctttctccgg gaaagtagaa ttacaaggaa aacgcttaga      540

gattgaacat tcggtgccca aaaaacaaag gagccggaaa attcaaatcc gaaatattcc      600

accccagctc cgatgggaag tactggacag cctgctggct cagtatggta cagtagagaa      660

ctgtgagcaa gtgaacaccg agagtgagac ggcagtggtg aatgtcacct attccaaccg      720

ggagcagacc aggcaagcca tcatgaagct gaatggccac cagttggaga accatgccct      780

gaaggtctcc tacatccccg atgagcagat agcacaggga cctgagaatg ggcgccgagg      840

gggctttggc tctcggggtc agccccgcca gggctcacct gtggcagcgg gggccccagc      900

caagcagcag caagtggaca tcccccttcg gctcctggtg cccacccagt atgtgggtgc      960

cattattggc aaggaggggg ccaccatccg caacatcaca aaacagaccc agtccaagat     1020

agacgtgcat aggaaggaga acgcaggtgc agctgaaaaa gccatcagtg tgcactccac     1080

ccctgagggc tgctcctccg cttgtaagat gatcttggag attatgcata aagaggctaa     1140

ggacaccaaa acggctgacg aggttcccct gaagatcctg gcccataata actttgtagg     1200

gcgtctcatt ggcaaggaag gacggaacct gaagaaggta gagcaagata ccgagacaaa     1260

aatcaccatc tcctcgttgc aagaccttac cctttacaac cctgagagga ccatcactgt     1320

gaagggggcc atcgagaatt gttgcagggc cgagcaggaa ataatgaaga aagttcggga     1380

ggcctatgag aatgatgtgg ctgccatgag cctgcagtct cacctgatcc ctggcctgaa     1440

cctggctgct gtaggtcttt tcccagcttc atccagcgca gtcccgccgc ctcccagcag     1500

cgttactggg gctgctccct atagctcctt tatgcaggct cccgagcagg agatggtgca     1560

ggtgtttatc cccgcccagg cagtgggcgc catcatcggc aagaaggggc agcacatcaa     1620

acagctctcc cggtttgcca gcgcctccat caagattgca ccacccgaaa cacctgactc     1680

caaagttcgt atggttatca tcactggacc gccagaggcc caattcaagg ctcagggaag     1740

aatctatggc aaactcaagg aggagaactt ctttggtccc aaggaggaag tgaagctgga     1800

gacccacata cgtgtgccag catcagcagc tggccgggtc attggcaaag gtggaaaaac     1860

ggtgaacgag ttgcagaatt tgacggcagc tgaggtggta gtaccaagag accagacccc     1920

tgatgagaac gaccaggtca tcgtgaaaat catcggacat ttctatgcca gtcagatggc     1980

tcaacggaag atccgagaca tcctggccca ggttaagcag cagcatcaga agggacagag     2040

taaccaggcc caggcacgga ggaagtgacc agcccctccc tgtcccttcg agtccaggac     2100

aacaacgggc agaaatcgag agtgtgctct ccccggcagg cctgagaatg agtgggaatc     2160

cgggacacct gggccgggct gtagatcagg tttgcccact tgattgagaa agatgttcca     2220

gtgaggaacc ctgatctctc agccccaaac acccacccaa ttggcccaac actgtctgcc     2280

cctcggggtg tcagaaattc tagcgcaagg cacttttaaa cgtggattgt ttaaagaagc     2340

tctccaggcc ccaccaagag ggtggatcac acctcagtgg gaagaaaaat aaaatttcct     2400

tcaggtttta aaaacatgca gagaggtgtt ttaatcagcc ttaaaggatg gttcatttct     2460

tgaccttaat gtttttccaa tcttcttccc cctacttggg taattgatta aaatacctcc     2520

atttacggcc tctttctata tttacactaa tttttttatc tttattgcta ccagaaaaaa     2580

atgcgaacga atgcattgct ttgcttacag tattgactca agggaaaaga actgtcagta     2640

tctgtagatt aattccaatc actccctaac caataggtac aatacggaat gaagaagagg     2700

ggaaaatggg gagaaagatg gttaaaatac ataataatcc acgtttaaaa ggagcgcact     2760

tgtggctgat ctatgccaga tcaccatctt caaattggca caactgaaat ttccccactc     2820

tgttggggct tccccaccac attcatgtcc ctctcccgtg taggtttcac attatgtcca     2880

ggtgcacata ggtggtattg aatgctcagc agggtagggg ctgaccactg tccctgattc     2940

ccatcgttct caggcggatt ttatattttt ttaaagtcta ttttaatgat tggatatgag     3000

cactgggaag gggacgctaa ctccccttga taaagtctcg gttccatgga ggacttgagt     3060

ggccccaaag gctgccacgg tgccctcacc ccagcccatg tgctcccata agggctggtt     3120

cctagaggca ggggttgtgg ggcactccca gccacggcac tgttaccttg gtggtgggac     3180

ttggaaccca accctgagct cccgataaag ctaaagtcca tcatctggca aattcagtaa     3240

attggagagt acttgcttct gtttgtatct gagaggaatt tttaactgac ggcttctgtc     3300

tccatgaatc attatcagca tgatgaaagg tgtgtctaaa aaacaattca gaataccagc     3360

agcattgtac agcaaggggt aaataagctt aatttattaa tttaccaggc ttaattaaga     3420

tcccatggag tgtttagccc ttgtgggaga cagaagccat cagttaaatg aggttaggcc     3480

tctcctccta atatactgat tgacaatgca tattagccag gtaatgcact ttagctaccc     3540

tggacaatgc tatcaagtgt gctgggaagg gaggaaggcc tctctacata tggaaaagcc     3600

catgcgtgga gttcccctcc tttcaacatt gcaacaacag taacaacaag acaaccgcaa     3660

catgtgggcg tagtcaggca atgctgtgtg cgaagtaaac tacctcaagg tatgaagtta     3720

cctcagcaat tattttcctt tttgttcccc ccaaccccat taaaaaaatt tttttttgat     3780

ttttgttttt ttgcagcttg ctgatatttt atataaaaaa gaaaagcaaa gcaaaagaga     3840

agctgatagt cttgaatatt ttattttttt aatgaaaaga aaaaacaaga aagttatgtt     3900

tcataatttc ttacaacatg agccagtaac cctttaggaa ctctctatgg agaacaggcc     3960

tggtgggaaa ggctttgggg gctgccccct taggaggagg ctagtgctaa gagggaaggc     4020

ccaggtttga gagagcccag aggggcagag cccagagcct tgtttggccc tgatctctga     4080

cttctagagc cccagctgct ggcggctgct ggaatatcct acctgatagg attaaaaggc     4140

ctagtggagc tgggggctct cagtggttaa acaatgccca acaaccaacc agctggccct     4200

tggtctcctc tctttcctcc tttggttaaa gagcatctca gccagctttt cccaccagtg     4260

gtgctgttga gatattttaa aatattgcct ccgttttatc gaggagagaa ataataacta     4320

aaaaatatac cctttaaaaa aacctatatt tctctgtcta aaaatatggg agctgagatt     4380

ccgttcgtgg aaaaaagaca aggccaccct ctcgccctca gagaggtcca cctggtttgt     4440

cattgcaatg cttttcattt tttttttttg ttattgtttc atttcagttc cgtcttgcta     4500

ttcttcctaa tctatatcca tagatctaag gggcaaacag atactagtta actgccccca     4560

cctctgtctc cctgtcttct ttagatcggt ctgattgatt ttaaaagtgg acccaaactt     4620

agggaattct tgatttaggg tggctggtgg caaggagggg caggggatat ggggacgtga     4680

ctgggacagg ttcctgcctt atcattttct ccctaggaca ttcccttgta gcccccagaa     4740

ttgtctggcc caaattgaat agaagcagaa aaacatttag ggataacatc aggccagtag     4800

aattaagcct ctccacctgt cccaaccata aaaagggtct cccagctttc catctctggc     4860

tctatatgct ttatcccaaa acaaagcaga taacgttcag acgtcggcca tttagtaatt     4920

taaagcgaat ttccagcagc aagcatgctt tgatatctgg ttcagactat catcaggaag     4980

aaaaaaaaat cccacagtac ctgaaatgtg attgttgcag tgttcagttt ccttgggggc     5040

ctgctccctt cacaccttga gcccaagtcc ttttccgttg gctgattcag ctcccagaag     5100

agacgaggaa gtgtgtggca agggactgga aaacttcact tgcttggatt aggcaaggct     5160

ccactcattg ttgatatttg cccagcagga aaatcatgta agttatacca ccagaaagca     5220

aaaggagcat ggtttggtgg ttaaggttta gtgggatgaa ggacctgtct tggtgggccg     5280

ggccctcttg tgccccgtag gctaggtctt agggcaactc cttgccctcc tgctcagcac     5340

ctccatttcc ccatccttgg tgagataaca agctatcgcg aaaagcactt gggagatttg     5400

gatgatttga gaagagtgac ttaaaaaaaa tgcttctgtg ctctaagata tatatgtgtg     5460

tgtgtgtgct acatatatat ttttaagaaa ggaccatctc tttaggatat atttttaaat     5520

tctttgaaac acataaccaa aatggtttga ttcactgact gactttgaag ctgcatctgc     5580

cagttacacc ccaaatggct ttaatcccct ctcgggtctg gttgcctttt gcagtttggg     5640

ttgtggactc agctcctgtg aggggtctgg ttaggagaga gccattttta aggacaggga     5700

gttttatagc ccttttctac tttcctcccc tcctcccagt ccttatcaat cttttttcct     5760

ttttcctgac cccctccttc tggaggcagt tgggagctat ccttgtttat gcctcactat     5820

tggcagaaaa gaccccattt aaaacccaga gaacactgga gggggatgct ctagttggtt     5880

ctgtgtccat tttcctctgt gccaaagaca gacagacaga ggctgagaga ggctgttcct     5940

gaatcaaagc aatagccagc tttcgacaca tacctggctg tctgaggagg aaggcctcct     6000

ggaaactggg agctaagggc gaggcccttc ccttcagagg ctcctggggg attagggtgt     6060

ggtgtttgcc aagccaaggg gtagggagcc gagaaattgg tctgtcggct cctggttgca     6120

ctttggggaa ggagaggaag tttggggctc caggtagctc cctgttgtgg gactgctctg     6180

tcccctgccc ctactgcaga gatagcactg ccgagttccc ttcaggcctg gcagacgggc     6240

agtgaggagg ggcctcagtt agctctcaag ggtgccttcc cctcctccca acccagacat     6300

accctctgcc aaactgggaa ccagcagtgc tagtaactac ctcacagagc cccagagggc     6360

ctgcttgagc cttcttgctc cacaggagaa gctggtgcct ctaggcaacc ccttcctccc     6420

acctctcatc aggggtgggg gttctccttt ctttcccctg aagtgtttat ggggagatcc     6480

tagtggcttt gccattcaaa ccactcgact gtttgcctgt ttcttgaaaa ccagtagaag     6540

ggaaacagca cagcctgtca cagtaattgc aggaagattg aagaaaaatc ctcatcaatg     6600

ccaggggaca taaaagccat ttcccttcca aatactcgac aatttagatg cagaacattt     6660

ctctgtattc agacttagag taacaccagc tgaaaactgc agtttctttc ctttggatac     6720

ataaggcttc tctatcgggg tacgggacag ggaggaggcc tcatgtctga agggggattt     6780

aggggcgaga gccccagccc tgaccctcgg tcctgtgcac cgctttgggg cacagtctga     6840

tggcgccttt gctggcgcct tagtatggtt gactccggat ggacaaaaga aaaaaaattt     6900

tttttcttga atgaaatagc aggaagctcc tcgggagcat gtgttttgat taaccgcagg     6960

tgatggatgc tacgagtata aatggattaa ctacctcaat ccttacagta agattggaac     7020

taagggcagg gactcatgca taagggtatg aatcccagcc aggacaagtg agttgaggct     7080

tgtgccacaa aaggtttgtc cttggggaac aggcaggcct gccaggatcc cccccatatc     7140

gattgggctg ggagggctgg ccatgaggtc cccactttct gctttccttg cccatgtgtc     7200

acccctttgg cctccagctt gtccctctct cactttctat agctttgttg gaccagatgg     7260

tgaggaaagg aatggcctct tcccttctag agggggctgg ctggagtgag acctggggct     7320

tggcctggaa cccaccacac agccccaaag tcaggaagcc tggggaaacc agagctgaga     7380

cctcttcaac agggtttctt tgagatccta cacctccatt gggccctttt tcagtcttca     7440

atgggggccc agttggctct agaaggagaa gaggtgaagc aggatccttt gccctggggg     7500

agtctgaggg cgcggtcctt ggactcattc aggccgtctt tgtagttggg ggagttccac     7560

tgggcgatcc cagcccctcc ccacccaccc tctaatggac ctcctcatag aagccccatt     7620

tcacttttgt tttatctacc tcttagcaaa acaatagata aattaggtag tggcagctcc     7680

acttgcttag gttagggggg gaaaaagatt tctttttcca aaggaaaaaa atattacctt     7740

gagaatactt tccaaaaaat aaaattaaaa aaaaaaaaac caaaaaaaaa aatttttttt     7800

taaaagggag acattttcca gtgaccactg gattgtttta atttcccaag cttttttttc     7860

ccccataaat aagtttcact ctttggcgat tttcttcact tgtttaagat aacgtgctag     7920

ctattccaac aggtaacagc tttcacagtc tgcccctggc ctgtctcacc ccatccccca     7980

ccctattcct gccagtgagt ccttcctgtg cttctctccc ttctcccctc ccagccagct     8040

gacttcagtc acccctgtcc cccctcccct gccaataagc tcccccagga ataaaggctt     8100

tgttttgggg atgcttaaat cttgactggc acttcccggc tgtgggggct ggggagccac     8160

ttgtaacatt tctgtgcaga ttttatgtta gccactgcta tgtaaaagca cgttcaaaat     8220

gaatttcagc agattatgtg ttaccataat gaataaacgt cctctatcac catttggagt     8280

ctcccttttc tccaggatct tgatcctggt ccccaaaacc agagtgaatc aaaagagctt     8340

cctcccctga ggcaaagtgg atttgtaagc agttctgaaa catcacttac tcagaagagg     8400

gaacgatgta ttttgatgag tgcaaattgg gaagagctgg aggcctactg cttgggacag     8460

tttttttttt tttttttttt ttaaatatga gtgctagctt attctgtaat tgcggcaact     8520

ttgaaaattg tattttactg gaaatctgcc agccatcacc acccgatttt gattgtatcc     8580

ttcctcccat cctttaatct gttcattgct ttgggggagg tggggcagct ggctcacacg     8640

ttggagtttg ttctttgatg gatgaacgaa cactccagtt ttctttcccg tgaaggttgt     8700

ttcagccaca aaccacttca ttttgctgtt tcaatttcaa aataaaagga aacttatatt     8760

gaaagacaa                                                             8769


<210>  305
<211>  3547
<212>  DNA
<213>  homo sapiens

<400>  305
gagagacgag ggcagcggag gaggcgagga gcgccgggta ccgggccggg ggagccgcgg       60

gctctcgggg aagagacgga tgatgaacaa gctttacatc gggaacctga gccccgccgt      120

caccgccgac gacctccggc agctctttgg ggacaggaag ctgcccctgg cgggacaggt      180

cctgctgaag tccggctacg ccttcgtgga ctaccccgac cagaactggg ccatccgcgc      240

catcgagacc ctctcgggta aagtggaatt gcatgggaaa atcatggaag ttgattactc      300

agtctctaaa aagctaagga gcaggaaaat tcagattcga aacatccctc ctcacctgca      360

gtgggaggtg ttggatggac ttttggctca atatgggaca gtggagaatg tggaacaagt      420

caacacagac acagaaaccg ccgttgtcaa cgtcacatat gcaacaagag aagaagcaaa      480

aatagccatg gagaagctaa gcgggcatca gtttgagaac tactccttca agatttccta      540

catcccggat gaagaggtga gctccccttc gccccctcag cgagcccagc gtggggacca      600

ctcttcccgg gagcaaggcc acgcccctgg gggcacttct caggccagac agattgattt      660

cccgctgcgg atcctggtcc ccacccagtt tgttggtgcc atcatcggaa aggagggctt      720

gaccataaag aacatcacta agcagaccca gtcccgggta gatatccata gaaaagagaa      780

ctctggagct gcagagaagc ctgtcaccat ccatgccacc ccagagggga cttctgaagc      840

atgccgcatg attcttgaaa tcatgcagaa agaggcagat gagaccaaac tagccgaaga      900

gattcctctg aaaatcttgg cacacaatgg cttggttgga agactgattg gaaaagaagg      960

cagaaatttg aagaaaattg aacatgaaac agggaccaag ataacaatct catctttgca     1020

ggatttgagc atatacaacc cggaaagaac catcactgtg aagggcacag ttgaggcctg     1080

tgccagtgct gagatagaga ttatgaagaa gctgcgtgag gcctttgaaa atgatatgct     1140

ggctgttaac acccactccg gatacttctc cagcctgtac ccccatcacc agtttggccc     1200

gttcccgcat catcactctt atccagagca ggagattgtg aatctcttca tcccaaccca     1260

ggctgtgggc gccatcatcg ggaagaaggg ggcacacatc aaacagctgg cgagattcgc     1320

cggagcctct atcaagattg cccctgcgga aggcccagac gtcagcgaaa ggatggtcat     1380

catcaccggg ccaccggaag cccagttcaa ggcccaggga cggatctttg ggaaactgaa     1440

agaggaaaac ttctttaacc ccaaagaaga agtgaagctg gaagcgcata tcagagtgcc     1500

ctcttccaca gctggccggg tgattggcaa aggtggcaag accgtgaacg aactgcagaa     1560

cttaaccagt gcagaagtca tcgtgcctcg tgaccaaacg ccagatgaaa atgaggaagt     1620

gatcgtcaga attatcgggc acttctttgc tagccagact gcacagcgca agatcaggga     1680

aattgtacaa caggtgaagc agcaggagca gaaataccct cagggagtcg cctcacagcg     1740

cagcaagtga ggctcccaca ggcaccagca aaacaacgga tgaatgtagc ccttccaaca     1800

cctgacagaa tgagaccaaa cgcagccagc cagatcggga gcaaaccaaa gaccatctga     1860

ggaatgagaa gtctgcggag gcggccaggg actctgccga ggccctgaga accccagggg     1920

ccgaggaggg gcggggaagg tcagccaggt ttgccagaac caccgagccc cgcctcccgc     1980

cccccagggc ttctgcaggc ttcagccatc cacttcacca tccactcgga tctctcctga     2040

actcccacga cgctatccct tttagttgaa ctaacatagg tgaacgtgtt caaagccaag     2100

caaaatgcac accctttttc tgtggcaaat cgtctctgta catgtgtgta catattagaa     2160

agggaagatg ttaagatatg tggcctgtgg gttacacagg gtgcctgcag cggtaatata     2220

ttttagaaat aatatatcaa ataactcaac taactccaat ttttaatcaa ttattaattt     2280

ttttttcttt ttaaagagaa agcaggcttt tctagacttt aaagaataaa gtctttggga     2340

ggtctcacgg tgtagagagg agctttgagg ccacccgcac aaaattcacc cagagggaaa     2400

tctcgtcgga aggacactca cggcagttct ggatcacctg tgtatgtcaa cagaagggat     2460

accgtctcct tgaagaggaa actctgtcac tcctcatgcc tgtctagctc atacacccat     2520

ttctctttgc ttcacaggtt ttaaactggt tttttgcata ctgctatata attctctgtc     2580

tctctctgtt tatctctccc ctccctcccc tccccttctt ctccatctcc attcttttga     2640

atttcctcat ccctccatct caatcccgta tctacgcacc cccccccccc caggcaaagc     2700

agtgctctga gtatcacatc acacaaaagg aacaaaagcg aaacacacaa accagcctca     2760

acttacactt ggttactcaa aagaacaaga gtcaatggta cttgtcctag cgttttggaa     2820

gaggaaaaca ggaacccacc aaaccaacca atcaaccaaa caaagaaaaa attccacaat     2880

gaaagaatgt attttgtctt tttgcatttt ggtgtataag ccatcaatat tcagcaaaat     2940

gattcctttc tttaaaaaaa aaaaatgtgg aggaaagtag aaatttacca aggttgttgg     3000

cccagggcgt taaattcaca gattttttta acgagaaaaa cacacagaag aagctacctc     3060

aggtgttttt acctcagcac cttgctcttg tgtttccctt agagattttg taaagctgat     3120

agttggagca tttttttatt tttttaataa aaatgagttg gaaaaaaaat aagatatcaa     3180

ctgccagcct ggagaaggtg acagtccaag tgtgcaacag ctgttctgaa ttgtcttccg     3240

ctagccaaga acctatatgg ccttcttttg gacaaacctt gaaaatgttt atttaaaaaa     3300

aaaaaagatg acaaagaaaa acagagagag agaatattgg agatgtcctg aattttaata     3360

gggtacgcgc cattagggct ttttgcgcta aaggatgaac atgtactggt ttatgtggac     3420

aagccattat accaccagac tgcaatgcca gtttcctcta ctgcaaacag tgttctgtga     3480

caaaaaaaaa aaaaaaaaaa agaaaaaaaa agaaaaaaca gaaatatatc cagctaacaa     3540

gaaaaaa                                                               3547


<210>  306
<211>  4583
<212>  DNA
<213>  homo sapiens

<400>  306
gcggccgccc cggcggctcc tggaaccccg gttcgcggcg atgccagcca ccccagcgaa       60

gccgccgcag ttcagtgctt ggataatttg aaagtacaat agttggtttc cctgtccacc      120

cgccccactt cgcttgccat cacagcacgc ctatcggatg tgagaggaga agtcccgctg      180

ctcgggcact gtctatatac gcctaacacc tacatatatt ttaaaaacat taaatataat      240

taacaatcaa aagaaagagg agaaaggaag ggaagcatta ctgggttact atgcacttgc      300

gactgatttc ttggcttttt atcattttga actttatgga atacatcggc agccaaaacg      360

cctcccgggg aaggcgccag cgaagaatgc atcctaacgt tagtcaaggc tgccaaggag      420

gctgtgcaac atgctcagat tacaatggat gtttgtcatg taagcccaga ctattttttg      480

ctctggaaag aattggcatg aagcagattg gagtatgtct ctcttcatgt ccaagtggat      540

attatggaac tcgatatcca gatataaata agtgtacaaa atgcaaagct gactgtgata      600

cctgtttcaa caaaaatttc tgcacaaaat gtaaaagtgg attttactta caccttggaa      660

agtgccttga caattgccca gaagggttgg aagccaacaa ccatactatg gagtgtgtca      720

gtattgtgca ctgtgaggtc agtgaatgga atccttggag tccatgcacg aagaagggaa      780

aaacatgtgg cttcaaaaga gggactgaaa cacgggtccg agaaataata cagcatcctt      840

cagcaaaggg taacctgtgt cccccaacaa atgagacaag aaagtgtaca gtgcaaagga      900

agaagtgtca gaagggagaa cgaggaaaaa aaggaaggga gaggaaaaga aaaaaaccta      960

ataaaggaga aagtaaagaa gcaatacctg acagcaaaag tctggaatcc agcaaagaaa     1020

tcccagagca acgagaaaac aaacagcagc agaagaagcg aaaagtccaa gataaacaga     1080

aatcggtatc agtcagcact gtacactaga gggttccatg agattattgt agactcatga     1140

tgctgctatc tcaaccagat gcccaggaca ggtgctctag ccattaggac cacaaatgga     1200

catgtcagtt attgctctgt ctaaacaaca ttcccagtag ttgctatatt cttcatacaa     1260

gcatagttaa caacaaagag ccaaaagatc aaagaaggga tactttcaga tggttgtctt     1320

gtgtgcttct ctgcattttt aaaagacaag acattcttgt acatattatc aataggctat     1380

aagatgtaac aacgaaatga tgacatctgg agaagaaaca tcttttcctt ataaaaatgt     1440

gttttcaagc tgttgtttta agaagcaaaa gatagttctg caaattcaaa gatacagtat     1500

cccttcaaaa caaataggag ttcagggaag agaaacatcc ttcaaaggac agtgttgttt     1560

tgaccgggag atctagagag tgctcagaat tagggcctgg catttggaat cacaggattt     1620

atcatcacag aaacaactgt tttaagatta gttccatcac tctcatcctg tatttttata     1680

agaaacacaa gagtgcatac cagaattgaa tataccatat gggattggag aaagacaaat     1740

gtggaagaaa tcatagagct ggagactact tttgtgcttt acaaaactgt gaaggattgt     1800

ggtcacctgg aacaggtctc caatctatgt tagcactatg tggctcagcc tctgttaccc     1860

cttggattat atatcaacct gtaaacatgt gcctgtaact tacttccaaa aacaaaatca     1920

tacttattag aagaaaattc tgattttata gaaaaaaaat agagcaagga gaatataaca     1980

tgtttgcaaa gtcatgtgtt ttctttctca atgagggaaa aacaatttta ttacctgctt     2040

aatggtccac ctggaactaa aagggatact attttctaac aaggtatatc tagtagggga     2100

gaaagccacc acaataaata tatttgttaa tagtttttca agttttgttc actctgtttt     2160

attgtttgtt ttattgagaa attcttactc ttagagactc atgaattaag aaagagaatt     2220

ctgctaactc agagaacctg gttcctatgt aattcagaat atattacatt tctcagtaat     2280

atttgttttt tgaatccacc tttatctgag ccaatggaga tttacttata gcgtattagg     2340

agatatttat tccattttct tattttaatc aacattctaa ttatagacac atgggcctcc     2400

ctagctgatt tcactgctcc cccttcattg cttagaaatg ggcatcattt cttgtatgtc     2460

agatccccct gcatcttcaa catttagtct tttcttctcc atattttcta tctgtggatc     2520

tctttagggg attgaagtca ccctagctga aggcctcacc agtgtttcac agaggacaca     2580

gcccacccct tgcaggagga ggtatctctg agtgtgcagc acagaatcgc atgacccacc     2640

ttaaccttcc tgttgtcatg gaaggatgca cggctgctct gtccactgtg attcctagcc     2700

ctctcaagat cactgctttc tgaagaattt gcaatgactc tggcttctgg ctgcttatct     2760

ctggacaccc gttctccacc agttgtacag ttcatgtaat ctacttggct taattgattt     2820

tccacttctc tcttcctctt ctaagatata aacattttaa atgatttatt cctgtttctt     2880

attctggtgt ttctttcctt gtccctatga gataagtgtc tcaactcact aaatctattc     2940

ccaatgtata aaataattct aattccattt tcagctaaaa catatattac caagaagaaa     3000

caaactttat cctacagaat gatgttaggt agaaatatgt ccccaggttt gagacctttc     3060

ggatgatttc atataccatc tttcttctga gtgttaccca gtcaagtata agtagccaaa     3120

ttatttttgc acatctttct gtttctcatg tcttcattta ttcaacaagc acttactggg     3180

aaggtctaca cctgcatagg caatgctgga aaaagggtta agtaaaccag gacatgacaa     3240

tggtggcaaa tgactatcag gtcttcccat gtgtttgact caaacttatt accctatggt     3300

ccttctgaca atggcagaag gtctgaatcc ttgatgctaa acttatataa aagtagaatt     3360

attacaaagg aaaaagaaat aaaaactaac attcattttc atatgttgga tgaaatataa     3420

atgaagaaaa agataacatc aattttaact gtaattctcc atccaccagt aacagatcct     3480

taagacaata gaatcataca gtattcaaac cagcagcctt ctcaaatttg agcaaaaact     3540

ctatcaacct ctggtaaagt tcctacacta gtcacagaag gtgttaactt tctactctga     3600

ttctgtctcc ataatggggt aaactgttga tagtttaccc catcaacaga tggtcggtaa     3660

attattgatt cgaagaatcg agagagtgca gcaacataaa tctgttaatg tctgatcaag     3720

ctcctgccct gttctccgaa ttcagcttca taattaaggg aaggcctgtt ttctatcctc     3780

agatttaggt tctagtagca gttgtgtaac cactagtgag tcacttaact cctctgggtc     3840

cccatttctc atgtgcaaca agaaagaggg gaactggaga tgatcactct agttccagac     3900

aagggaacat ttcacacttt gtttacttca gggtgatgtc cctgagtcct cattagtgac     3960

tgcgtccttt ggaagttatc ccaaccctgc ttttctcaaa agtgaaaatg tataggctct     4020

cagaggagac agatttaact ctgcttctct aatgttattg aattaaaagc tgttcacatt     4080

agtggttatt aaatattgaa ataacactgg gaagaaaaag catatataaa tacagctaaa     4140

aacaagaata gatattcatt ctcacaaagg gagacagcaa agaaaatgga aagtgcactg     4200

gtgctagcgt tagacagctt gtgttaatgt ctcaattctg ctactaactg gttgcagctt     4260

gtgtgacctt gggcacattg tatgatctcg cagaatatca tcccaaatct gcaaaatgga     4320

attggcatca tctcttttgc aagattgtta tgagaattaa aaggttcttc attcaatata     4380

ataataaata ttttgtatat aaatgaatat caattaaaag ttatgactaa ttccacaagt     4440

caaacatata aattttattt cttgattcat gatatgtgat agtattcata aaaatgtaca     4500

tgcatgataa tttcaaggaa taagtatata tgtgagaatc atggaaatga aattaataat     4560

attaactagt aattaaattg taa                                             4583


<210>  307
<211>  3327
<212>  DNA
<213>  homo sapiens

<400>  307
ggaagaggag gggggagaag gaggagctga agcgggaaga gcggcaggca gcggctcggc       60

ggagttgcag cagaggcggc ggcgacgctg agacaccgca gcttccctga gcgccgagtc      120

cctccgggga cagcagcagg gagcgcccgc gcagccaccg agcctctgcc cagccaagcc      180

gccgtcgccg cgccggggga ccgccagcca tggccgcgcc gggggatccg caggacgagc      240

tgctgccgct ggccggcccc gggtcccagt ggctcaggca ccggggggag ggggagaacg      300

aagcggtgac gccgaaaggg gccacgccgg cgccgcaggc tggggagccc agcccggggt      360

tgggcgccag ggcccgggaa gcggcgtcgc gggaagccgg ctcgggcccc gcccggcagt      420

cgcccgttgc catggaaact gcatccacag gtgtggcagg tgtttccagt gccatggacc      480

acaccttctc aacaacatca aaagatgggg aaggatcgtg ttacacatct ctcatttctg      540

acatctgcta tccacctcag gaggattcta catattttac tggaattctt cagaaggaaa      600

atggccacgt caccatttca gagagccctg aggagctggg tacacccggc ccctccttac      660

cagatgtgcc tgggatagag tctcgtggct tatttagttc tgattctgga atagagatga      720

ctcctgcaga gtccacggaa gtgaacaaga tcttagcaga ccctctggac cagatgaaag      780

cagaggccta taaatacatt gacataacca gacccgagga ggtgaagcac caagaacaac      840

atcaccccga gctggaagat aaagacttgg actttaagaa taaagacact gacatctcaa      900

ttaaacctga aggagtccgt gaacctgaca aaccagctcc tgtggaggga aaaatcatca      960

aggaccattt attggaagaa tccacatttg ctccatacat agatgatctc tctgaagaac     1020

agcgcagggc tcctcagatc accacccctg tcaaaatcac actgacggaa atagaacctt     1080

ctgttgaaac cactacccaa gagaagaccc ctgagaagca agatatatgt ctaaagccaa     1140

gtcctgacac agtccccact gtcactgtct cggagcctga agacgacagc ccaggatcta     1200

tcacccctcc atcttctgga acagaaccat ctgctgcaga atcccagggg aaaggcagca     1260

tctccgagga tgagctgatc accgccatca aagaagcaaa gggattatcg tatgaaaccg     1320

ccgagaaccc acggccggtg ggccagctgg ccgacaggcc cgaggtcaag gccaggtccg     1380

gaccgccaac catccccagc cccctggacc acgaggccag cagcgcggag tcgggggact     1440

cagagatcga gctggtgtcc gaggacccca tggccgcgga ggacgcgctg ccctcaggct     1500

atgtgagctt tggccacgtg ggcggcccgc cgccctcgcc cgcctcgcca tccatccagt     1560

acagcatcct gagggaggag cgcgaggccg agctggacag cgagctcatc atcgagtcgt     1620

gcgacgcctc ctcggcctcg gaggagagcc ccaagcggga gcaggactca cccccgatga     1680

agcccagcgc cctggatgcc atccgggagg agactggcgt ccgggccgag gagcgtgcgc     1740

caagccggcg gggcctggcc gagccgggtt ccttcctcga ctacccctca actgagcccc     1800

agcctggccc cgagctgccc cctggagacg gagccctgga gcctgagacg cccatgttgc     1860

cacggaagcc tgaagaagac tcgagttcca accaaagtcc tgcggccaca aagggccctg     1920

ggcctctagg tcctggcgcc ccgcccccac tgctgtttct caataagcaa aaagctattg     1980

acctgttgta ttggcgggac atcaagcaga cgggcatcgt gtttgggagt ttcctgctgc     2040

tgctcttctc cctgacccag ttcagcgtgg tgagcgtcgt ggcctacctg gccctggccg     2100

cactctcagc caccatcagt ttccgcatct acaagtctgt tttacaagca gtgcagaaaa     2160

ccgacgaagg ccaccctttc aaggcctact tggagcttga gatcaccctt tctcaggagc     2220

agattcagaa gtacacggac tgcctgcagt tctacgtgaa cagcacactt aaggaactga     2280

ggaggctctt ccttgtccag gacctggtgg attccttaaa atttgcagtc ctgatgtggc     2340

tcctgaccta cgttggcgct ctcttcaatg gcctgaccct gctgctcatg gctgtggttt     2400

caatgtttac tctacctgta gtgtatgtta agcaccaggc acagattgac caatatctgg     2460

gacttgtgag gactcacata aatgctgttg tggcaaagat tcaggctaaa atcccaggcg     2520

ctaagaggca cgctgagtaa actgatttcc caccggggac tggacacaaa caggaatgtc     2580

tggagtggta acagctctct tcttactcat tactgcaaat tgattgtctt tcccccctcc     2640

ctccagtacc ataatcttag agacaaacct taaaacagct gtttttaggc tgttccttgt     2700

actcttagga tatttgagtc acttgtgtca accactaaag tatagagaaa agtgtattag     2760

atgtggtttt taattttgtg ttgctaaaaa aagtgcatga tggtgagagc ccaagttatc     2820

tttccctctt cggtgttctt cttctcttct ctgcaatgct tctgtagctt ctaatgttcc     2880

ccgtggctag gcctttcctg ccgagtgctc tgatgcaata gtggaaatcg cttatatgtc     2940

cttgggttgc tggttggatt aatctttaat aacaatatat agaattgtag actgatgttt     3000

tagcattttt ccaacacaca caacgtaaaa ataaaagcag tcgaccgcac ttatggtaat     3060

cagttttgta taacttaaaa taattaaata aatgaataaa tccaaaacaa acatgcagta     3120

cttttgttgt atgggattgg tgggctgatt tacatgtatg gttactaaaa agtaccagca     3180

tgttaacttt attacaattt gtattacttt ctctgtagtt cctaatggat tcaattacgg     3240

actctggata tttgcactta tgtacttgat actgaatgca taaataaatg ttactaaatg     3300

tagaatgtta aaaaaaaaaa aaaaaaa                                         3327


<210>  308
<211>  1722
<212>  DNA
<213>  homo sapiens

<400>  308
agaaccgctt tacccgtctc cagggtagca cccttgggca gcccagccaa cgctgtcgcg       60

tggagcggcg cccgcatccc catgcgcgca ggcggctccg gggccgcgcc gcgctgattc      120

gctgccggcc gcgcagactg cggcgccagc gacgctcccg cccctcaccg cgcgccgcct      180

ggtgcagcct cagtctctcc gcagccgcgc ggccactgcg agcccagccg cagcagccgg      240

gcaccaacgc ttgagtgcac gctcggcgcc cccgaggaga gccacggcga gcccccaaag      300

cccgcacgat gcaggccact gccgattcca ccaagatgga ctgtgtgtgg agcaactgga      360

aaagtcaggc tattgacctg ttgtattggc gggacatcaa gcagacgggc atcgtgtttg      420

ggagtttcct gctgctgctc ttctccctga cccagttcag cgtggtgagc gtcgtggcct      480

acctggccct ggccgcactc tcagccacca tcagtttccg catctacaag tctgttttac      540

aagcagtgca gaaaaccgac gaaggccacc ctttcaaggc ctacttggag cttgagatca      600

ccctttctca ggagcagatt cagaagtaca cggactgcct gcagttctac gtgaacagca      660

cacttaagga actgaggagg ctcttccttg tccaggacct ggtggattcc ttaaaatttg      720

cagtcctgat gtggctcctg acctacgttg gcgctctctt caatggcctg accctgctgc      780

tcatggctgt ggtttcaatg tttactctac ctgtagtgta tgttaagcac caggcacaga      840

ttgaccaata tctgggactt gtgaggactc acataaatgc tgttgtggca aagattcagg      900

ctaaaatccc aggcgctaag aggcacgctg agtaaactga tttcccaccg gggactggac      960

acaaacagga atgtctggag tggtaacagc tctcttctta ctcattactg caaattgatt     1020

gtctttcccc cctccctcca gtaccataat cttagagaca aaccttaaaa cagctgtttt     1080

taggctgttc cttgtactct taggatattt gagtcacttg tgtcaaccac taaagtatag     1140

agaaaagtgt attagatgtg gtttttaatt ttgtgttgct aaaaaaagtg catgatggtg     1200

agagcccaag ttatctttcc ctcttcggtg ttcttcttct cttctctgca atgcttctgt     1260

agcttctaat gttccccgtg gctaggcctt tcctgccgag tgctctgatg caatagtgga     1320

aatcgcttat atgtccttgg gttgctggtt ggattaatct ttaataacaa tatatagaat     1380

tgtagactga tgttttagca tttttccaac acacacaacg taaaaataaa agcagtcgac     1440

cgcacttatg gtaatcagtt ttgtataact taaaataatt aaataaatga ataaatccaa     1500

aacaaacatg cagtactttt gttgtatggg attggtgggc tgatttacat gtatggttac     1560

taaaaagtac cagcatgtta actttattac aatttgtatt actttctctg tagttcctaa     1620

tggattcaat tacggactct ggatatttgc acttatgtac ttgatactga atgcataaat     1680

aaatgttact aaatgtagaa tgttaaaaaa aaaaaaaaaa aa                        1722


<210>  309
<211>  3327
<212>  DNA
<213>  homo sapiens

<400>  309
ggaagaggag gggggagaag gaggagctga agcgggaaga gcggcaggca gcggctcggc       60

ggagttgcag cagaggcggc ggcgacgctg agacaccgca gcttccctga gcgccgagtc      120

cctccgggga cagcagcagg gagcgcccgc gcagccaccg agcctctgcc cagccaagcc      180

gccgtcgccg cgccggggga ccgccagcca tggccgcgcc gggggatccg caggacgagc      240

tgctgccgct ggccggcccc gggtcccagt ggctcaggca ccggggggag ggggagaacg      300

aagcggtgac gccgaaaggg gccacgccgg cgccgcaggc tggggagccc agcccggggt      360

tgggcgccag ggcccgggaa gcggcgtcgc gggaagccgg ctcgggcccc gcccggcagt      420

cgcccgttgc catggaaact gcatccacag gtgtggcagg tgtttccagt gccatggacc      480

acaccttctc aacaacatca aaagatgggg aaggatcgtg ttacacatct ctcatttctg      540

acatctgcta tccacctcag gaggattcta catattttac tggaattctt cagaaggaaa      600

atggccacgt caccatttca gagagccctg aggagctggg tacacccggc ccctccttac      660

cagatgtgcc tgggatagag tctcgtggct tatttagttc tgattctgga atagagatga      720

ctcctgcaga gtccacggaa gtgaacaaga tcttagcaga ccctctggac cagatgaaag      780

cagaggccta taaatacatt gacataacca gacccgagga ggtgaagcac caagaacaac      840

atcaccccga gctggaagat aaagacttgg actttaagaa taaagacact gacatctcaa      900

ttaaacctga aggagtccgt gaacctgaca aaccagctcc tgtggaggga aaaatcatca      960

aggaccattt attggaagaa tccacatttg ctccatacat agatgatctc tctgaagaac     1020

agcgcagggc tcctcagatc accacccctg tcaaaatcac actgacggaa atagaacctt     1080

ctgttgaaac cactacccaa gagaagaccc ctgagaagca agatatatgt ctaaagccaa     1140

gtcctgacac agtccccact gtcactgtct cggagcctga agacgacagc ccaggatcta     1200

tcacccctcc atcttctgga acagaaccat ctgctgcaga atcccagggg aaaggcagca     1260

tctccgagga tgagctgatc accgccatca aagaagcaaa gggattatcg tatgaaaccg     1320

ccgagaaccc acggccggtg ggccagctgg ccgacaggcc cgaggtcaag gccaggtccg     1380

gaccgccaac catccccagc cccctggacc acgaggccag cagcgcggag tcgggggact     1440

cagagatcga gctggtgtcc gaggacccca tggccgcgga ggacgcgctg ccctcaggct     1500

atgtgagctt tggccacgtg ggcggcccgc cgccctcgcc cgcctcgcca tccatccagt     1560

acagcatcct gagggaggag cgcgaggccg agctggacag cgagctcatc atcgagtcgt     1620

gcgacgcctc ctcggcctcg gaggagagcc ccaagcggga gcaggactca cccccgatga     1680

agcccagcgc cctggatgcc atccgggagg agactggcgt ccgggccgag gagcgtgcgc     1740

caagccggcg gggcctggcc gagccgggtt ccttcctcga ctacccctca actgagcccc     1800

agcctggccc cgagctgccc cctggagacg gagccctgga gcctgagacg cccatgttgc     1860

cacggaagcc tgaagaagac tcgagttcca accaaagtcc tgcggccaca aagggccctg     1920

ggcctctagg tcctggcgcc ccgcccccac tgctgtttct caataagcaa aaagctattg     1980

acctgttgta ttggcgggac atcaagcaga cgggcatcgt gtttgggagt ttcctgctgc     2040

tgctcttctc cctgacccag ttcagcgtgg tgagcgtcgt ggcctacctg gccctggccg     2100

cactctcagc caccatcagt ttccgcatct acaagtctgt tttacaagca gtgcagaaaa     2160

ccgacgaagg ccaccctttc aaggcctact tggagcttga gatcaccctt tctcaggagc     2220

agattcagaa gtacacggac tgcctgcagt tctacgtgaa cagcacactt aaggaactga     2280

ggaggctctt ccttgtccag gacctggtgg attccttaaa atttgcagtc ctgatgtggc     2340

tcctgaccta cgttggcgct ctcttcaatg gcctgaccct gctgctcatg gctgtggttt     2400

caatgtttac tctacctgta gtgtatgtta agcaccaggc acagattgac caatatctgg     2460

gacttgtgag gactcacata aatgctgttg tggcaaagat tcaggctaaa atcccaggcg     2520

ctaagaggca cgctgagtaa actgatttcc caccggggac tggacacaaa caggaatgtc     2580

tggagtggta acagctctct tcttactcat tactgcaaat tgattgtctt tcccccctcc     2640

ctccagtacc ataatcttag agacaaacct taaaacagct gtttttaggc tgttccttgt     2700

actcttagga tatttgagtc acttgtgtca accactaaag tatagagaaa agtgtattag     2760

atgtggtttt taattttgtg ttgctaaaaa aagtgcatga tggtgagagc ccaagttatc     2820

tttccctctt cggtgttctt cttctcttct ctgcaatgct tctgtagctt ctaatgttcc     2880

ccgtggctag gcctttcctg ccgagtgctc tgatgcaata gtggaaatcg cttatatgtc     2940

cttgggttgc tggttggatt aatctttaat aacaatatat agaattgtag actgatgttt     3000

tagcattttt ccaacacaca caacgtaaaa ataaaagcag tcgaccgcac ttatggtaat     3060

cagttttgta taacttaaaa taattaaata aatgaataaa tccaaaacaa acatgcagta     3120

cttttgttgt atgggattgg tgggctgatt tacatgtatg gttactaaaa agtaccagca     3180

tgttaacttt attacaattt gtattacttt ctctgtagtt cctaatggat tcaattacgg     3240

actctggata tttgcactta tgtacttgat actgaatgca taaataaatg ttactaaatg     3300

tagaatgtta aaaaaaaaaa aaaaaaa                                         3327


<210>  310
<211>  1722
<212>  DNA
<213>  homo sapiens

<400>  310
agaaccgctt tacccgtctc cagggtagca cccttgggca gcccagccaa cgctgtcgcg       60

tggagcggcg cccgcatccc catgcgcgca ggcggctccg gggccgcgcc gcgctgattc      120

gctgccggcc gcgcagactg cggcgccagc gacgctcccg cccctcaccg cgcgccgcct      180

ggtgcagcct cagtctctcc gcagccgcgc ggccactgcg agcccagccg cagcagccgg      240

gcaccaacgc ttgagtgcac gctcggcgcc cccgaggaga gccacggcga gcccccaaag      300

cccgcacgat gcaggccact gccgattcca ccaagatgga ctgtgtgtgg agcaactgga      360

aaagtcaggc tattgacctg ttgtattggc gggacatcaa gcagacgggc atcgtgtttg      420

ggagtttcct gctgctgctc ttctccctga cccagttcag cgtggtgagc gtcgtggcct      480

acctggccct ggccgcactc tcagccacca tcagtttccg catctacaag tctgttttac      540

aagcagtgca gaaaaccgac gaaggccacc ctttcaaggc ctacttggag cttgagatca      600

ccctttctca ggagcagatt cagaagtaca cggactgcct gcagttctac gtgaacagca      660

cacttaagga actgaggagg ctcttccttg tccaggacct ggtggattcc ttaaaatttg      720

cagtcctgat gtggctcctg acctacgttg gcgctctctt caatggcctg accctgctgc      780

tcatggctgt ggtttcaatg tttactctac ctgtagtgta tgttaagcac caggcacaga      840

ttgaccaata tctgggactt gtgaggactc acataaatgc tgttgtggca aagattcagg      900

ctaaaatccc aggcgctaag aggcacgctg agtaaactga tttcccaccg gggactggac      960

acaaacagga atgtctggag tggtaacagc tctcttctta ctcattactg caaattgatt     1020

gtctttcccc cctccctcca gtaccataat cttagagaca aaccttaaaa cagctgtttt     1080

taggctgttc cttgtactct taggatattt gagtcacttg tgtcaaccac taaagtatag     1140

agaaaagtgt attagatgtg gtttttaatt ttgtgttgct aaaaaaagtg catgatggtg     1200

agagcccaag ttatctttcc ctcttcggtg ttcttcttct cttctctgca atgcttctgt     1260

agcttctaat gttccccgtg gctaggcctt tcctgccgag tgctctgatg caatagtgga     1320

aatcgcttat atgtccttgg gttgctggtt ggattaatct ttaataacaa tatatagaat     1380

tgtagactga tgttttagca tttttccaac acacacaacg taaaaataaa agcagtcgac     1440

cgcacttatg gtaatcagtt ttgtataact taaaataatt aaataaatga ataaatccaa     1500

aacaaacatg cagtactttt gttgtatggg attggtgggc tgatttacat gtatggttac     1560

taaaaagtac cagcatgtta actttattac aatttgtatt actttctctg tagttcctaa     1620

tggattcaat tacggactct ggatatttgc acttatgtac ttgatactga atgcataaat     1680

aaatgttact aaatgtagaa tgttaaaaaa aaaaaaaaaa aa                        1722


<210>  311
<211>  2934
<212>  DNA
<213>  homo sapiens

<400>  311
gggagcgccg gggaggcggg cggaggcggg cggaggcggg gggcggggag cccgaggggt       60

ggaagccggc ggcggccgag cggggtcagt tctctgtagt gtttgccaat gttggagccg      120

tctgcaaagt gtccccggca agaagaggct gcctaccaca aggactttag cttacttttt      180

aaagattgaa gaaaaaaaag aagacagaaa aagaagaact caaagataca caaagtaatt      240

tgaaccaagg ctcagaagtt tttggagccg tgagggatac agcagtttgg tcaatattgt      300

cttaacatgc ttcaaataaa tcagatgttc tcagtgcagc tgagtcttgg tgagcagaca      360

tgggaatccg aaggcagcag tataaagaag gctcagcagg ctgttgccaa taaagctttg      420

actgaatcta cgcttcccaa accagttcag aagccaccca aaagtaatgt taacaataac      480

ccaggcagta taactccaac tgtggaactg aatgggcttg ctatgaaaag gggagagcct      540

gccatctaca ggccattaga tccaaagcca ttcccaaatt atagagctaa ttacaacttt      600

cggggcatgt acaatcagag gtatcattgc ccagtgccta agatctttta tgttcagctc      660

actgtaggaa ataatgaatt ttttggggaa ggaaagactc gacaagctgc tagacacaat      720

gctgcaatga aagccctcca agcactgcag aatgaaccta ttccagaaag atctcctcag      780

aatggtgaat caggaaagga tgtggatgat gacaaagatg caaataagtc tgagatcagc      840

ttagtgtttg aaattgctct gaagcgaaat atgcctgtca gttttgaggt tattaaagaa      900

agtggaccac cacatatgaa aagctttgtt actcgagtgt cagtaggaga gttctctgca      960

gaaggagaag gaaatagcaa aaaactctcc aagaagcgcg ctgcgaccac cgtcttacag     1020

gagcttaaaa aacttccacc tcttcctgtg gtggaaaagc caaaactatt ttttaaaaaa     1080

cgccctaaaa caatagtaaa ggccggacca gaatatggcc aagggatgaa ccctattagc     1140

cgcctggcgc aaattcaaca ggccaaaaag gaaaaggagc cggattatgt tttgctttca     1200

gaaagaggaa tgcctcgacg tcgagaattt gtgatgcagg tgaaggtagg caatgaagtt     1260

gctacaggaa caggacctaa taaaaagata gccaaaaaaa atgctgcaga agcaatgctg     1320

ttacaacttg gttataaagc atccactaat cttcaggatc aacttgagaa gacaggggaa     1380

aacaaaggat ggagtggtcc aaagcctggg tttcctgaac caacaaataa tactccaaaa     1440

ggaattcttc atttgtctcc tgatgtttat caagagatgg aagccagccg ccacaaagta     1500

atctctggca ctactctagg ctatttgtca cccaaagata tgaaccaacc ttcaagctct     1560

ttcttcagta tatctcccac atcgaatagt tcagctacaa ttgccaggga actccttatg     1620

aatggaacat cttctacagc tgaagccata ggtttaaaag gaagttctcc tactccccct     1680

tgttctccag tacaaccttc aaaacaactg gaatatttag caaggattca aggctttcag     1740

gcagccttaa gtgccttgaa acaattttct gaacaaggac tggatccaat cgatggagca     1800

atgaatatcg aaaaaggttc tcttgaaaaa caagccaagc atctgagaga gaaagcggac     1860

aataaccagg cacccccggg ctccatcgct caggactgca agaaatcaaa ctcggccgtc     1920

tagcagctcc cagaacccgc ggctgccacc gcatccttat aaacctgtca gcacgcatga     1980

gggtgtctgt gttcagggaa atgaatgact aataccatta tttgagtctt atgtgaagac     2040

aacactattc taacacgaga gataatatac atggtactgt ttattcaact ggggaaaaat     2100

aaaactttga gcatttccct tggaactcga gatcagatca taactcattt gcctagaggc     2160

agcagaaatc tgatcctgct actggagctt aaaataacaa gtaaagaaaa gtgttagaaa     2220

caaagctaaa attttaacat gattaataat agagaagttg ggtttggttc tgttgttatg     2280

attgttttgt cgtggtgctt gtgttcagtt atattctctc tctctctcat ttcaaatact     2340

gcttgacaat tcgaaaatga accaatgatg tgctgtggaa tgtgatggtt gtcttcatat     2400

agagtcacat ggtttctctt tttatgcaga tatttataat cttcatccta tatcagtagg     2460

aataactata aggtgcacta caaaaagatg tatgcaaaca aacatgtttt aaatcaggtc     2520

agatatctga tgaaaaatac gaactaatgt taagagcaag tagtttcaac atactccagg     2580

aactgagaaa caaaacaaag caattgtggg ttttgagctc catatactct tagcaagtaa     2640

gggggcgtct tgcccctata tatcatcttc ccggattcca ctccctgttg tgggaatcgc     2700

gcccaccccc atccgtgtgt tgtagccact cacggtttgc atcaagagtg ttttttgtaa     2760

ctgcctctgg acttgggaca gtgagtagga tcaaaaataa ataatgtaca tgacggggaa     2820

gggaaaaacc tgttggagtt gcttccagcc agccacgctc cgggccagca tgttggaatc     2880

cagcgtggag cagatgcagt aaaaatgtgg ttggtttctg tgtgaaaaaa aaaa           2934


<210>  312
<211>  2888
<212>  DNA
<213>  homo sapiens

<400>  312
gggagcgccg gggaggcggg cggaggcggg cggaggcggg gggcggggag cccgaggggt       60

ggaagccggc ggcggccgag cggggtcagt tctctgtagt gtttgccaat gttggagccg      120

tctgcaaagt gtccccggca agaagaggct gcctaccaca aggactttag cttacttttt      180

aaagattgaa gaaaaaaaag aagacagaaa aagaagaact caaagataca caaagtaatt      240

tgaaccaagg ctcagaagtt tttggagccg tgagggatac agcagtttgg tcaatattgt      300

cttaacatgc ttcaaataaa tcaggcagta taactccaac tgtggaactg aatgggcttg      360

ctatgaaaag gggagagcct gccatctaca ggccattaga tccaaagcca ttcccaaatt      420

atagagctaa ttacaacttt cggggcatgt acaatcagag gtatcattgc ccagtgccta      480

agatctttta tgttcagctc actgtaggaa ataatgaatt ttttggggaa ggaaagactc      540

gacaagctgc tagacacaat gctgcaatga aagccctcca agcactgcag aatgaaccta      600

ttccagaaag atctcctcag aatggtgaat caggaaagga tgtggatgat gacaaagatg      660

caaataagtc tgagatcagc ttagtgtttg aaattgctct gaagcgaaat atgcctgtca      720

gttttgaggt tattaaagaa agtggaccac cacatatgaa aagctttgtt actcgagtgt      780

cagtaggaga gttctctgca gaaggagaag gaaatagcaa aaaactctcc aagaagcgcg      840

ctgcgaccac cgtcttacag gagcttaaaa aacttccacc tcttcctgtg gtggaaaagc      900

caaaactatt ttttaaaaaa cgccctaaaa caatagtaaa ggccggacca gaatatggcc      960

aagggatgaa ccctattagc cgcctggcgc aaattcaaca ggccaaaaag gaaaaggagc     1020

cggattatgt tttgctttca gaaagaggaa tgcctcgacg tcgagaattt gtgatgcagg     1080

tgaaggtagg caatgaagtt gctacaggaa caggacctaa taaaaagata gccaaaaaaa     1140

atgctgcaga agcaatgctg ttacaacttg gttataaagc atccactaat cttcaggatc     1200

aacttgagaa gacaggggaa aacaaaggat ggagtggtcc aaagcctggg tttcctgaac     1260

caacaaataa tactccaaaa ggaattcttc atttgtctcc tgatgtttat caagagatgg     1320

aagccagccg ccacaaagta atctctggca ctactctagg ctatttgtca cccaaagata     1380

tgaaccaacc ttcaagctct ttcttcagta tatctcccac atcgaatagt tcagctacaa     1440

ttgccaggga actccttatg aatggaacat cttctacagc tgaagccata ggtttaaaag     1500

gaagttctcc tactccccct tgttctccag tacaaccttc aaaacaactg gaatatttag     1560

caaggattca aggctttcag gttcactact gtgatagaca aagtggcaaa gagtgtgtga     1620

cctgtctgac attagcccct gtgcagatga ctttccatgc tattggaagc tccattgaag     1680

ccagccatga tcaggcagcc ttaagtgcct tgaaacaatt ttctgaacaa ggactggatc     1740

caatcgatgg agcaatgaat atcgaaaaag gttctcttga aaaacaagcc aagcatctga     1800

gagagaaagc ggacaataac caggcacccc cgggctccat cgctcaggac tgcaagaaat     1860

caaactcggc cgtctagcag ctcccagaac ccgcggctgc caccgcatcc ttataaacct     1920

gtcagcacgc atgagggtgt ctgtgttcag ggaaatgaat gactaatacc attatttgag     1980

tcttatgtga agacaacact attctaacac gagagataat atacatggta ctgtttattc     2040

aactggggaa aaataaaact ttgagcattt cccttggaac tcgagatcag atcataactc     2100

atttgcctag aggcagcaga aatctgatcc tgctactgga gcttaaaata acaagtaaag     2160

aaaagtgtta gaaacaaagc taaaatttta acatgattaa taatagagaa gttgggtttg     2220

gttctgttgt tatgattgtt ttgtcgtggt gcttgtgttc agttatattc tctctctctc     2280

tcatttcaaa tactgcttga caattcgaaa atgaaccaat gatgtgctgt ggaatgtgat     2340

ggttgtcttc atatagagtc acatggtttc tctttttatg cagatattta taatcttcat     2400

cctatatcag taggaataac tataaggtgc actacaaaaa gatgtatgca aacaaacatg     2460

ttttaaatca ggtcagatat ctgatgaaaa atacgaacta atgttaagag caagtagttt     2520

caacatactc caggaactga gaaacaaaac aaagcaattg tgggttttga gctccatata     2580

ctcttagcaa gtaagggggc gtcttgcccc tatatatcat cttcccggat tccactccct     2640

gttgtgggaa tcgcgcccac ccccatccgt gtgttgtagc cactcacggt ttgcatcaag     2700

agtgtttttt gtaactgcct ctggacttgg gacagtgagt aggatcaaaa ataaataatg     2760

tacatgacgg ggaagggaaa aacctgttgg agttgcttcc agccagccac gctccgggcc     2820

agcatgttgg aatccagcgt ggagcagatg cagtaaaaat gtggttggtt tctgtgtgaa     2880

aaaaaaaa                                                              2888


<210>  313
<211>  3039
<212>  DNA
<213>  homo sapiens

<400>  313
ctcggtggcg gcggcggcgg ccggctccag gccgggtttt ggcgccgccc gcctgctgcc       60

tcctggcggc tcctgaactc cagccccctc tctatcagcc gctcactccg tctcaatatg      120

tctcaagatg gcggccaatg tgggatcgat gtttcaatat tggaagcgct ttgatttaca      180

gcagctgcag agagaactcg atgccaccgc aacggtattg gcgaaccggc aggatgaaag      240

tgagcagtcc agaaagcggc ttatcgaaca gagccgggag ttcaagaaga acactccaga      300

ggatttgcgc aagcaggtag cgccgctgct gaagagtttc caaggagaga ttgatgcact      360

gagtaaaaga agcaaggaag ctgaagcagc tttcttgaat gtctacaaaa gattgattga      420

cgtcccagat cccgtaccag ctttggatct cggacagcaa ctccagctca aagtgcagcg      480

cctgcacgat attgaaacag agaaccagaa acttagggaa actctggaag aatacaacaa      540

ggaatttgct gaagtgaaaa atcaagaggt tacgataaaa gcacttaaag agaaaatccg      600

agaatatgaa cagacactga agaaccaagc cgaaaccata gctcttgaga aggaacagaa      660

gttacagaat gactttgcag aaaaggagag aaagctgcag gagacacaga tgtccaccac      720

ctcaaagctg gaggaagctg agcataaggt tcagagccta caaacagccc tggaaaaaac      780

tcgaacagaa ttatttgacc tgaaaaccaa atacgatgaa gaaactactg caaaggccga      840

cgagattgaa atgatcatga cggaccttga aagggcaaac cagagggcag aggtggctca      900

gagagaggcg gagaccttaa gggaacagct ctcatcggcc aatcactccc tccagctggc      960

ctcacagatc cagaaggcac cagacgtgga gcaggccata gaggtgctga cccgctccag     1020

cctagaagtt gagttggccg ccaaggagcg ggagatcgca cagctggtgg aggacgtgca     1080

gagactccag gccagcctca ccaagctgcg ggagaattcg gccagccaga tctcacagct     1140

tgagcagcag ctgagcgcca aaaacagcac actcaaacaa ctggaagaaa aactcaaagg     1200

ccaggctgac tatgaagagg tgaagaaaga gctgaacatt ctgaagtcca tggagtttgc     1260

accgtccgag ggcgctggga cacaggatgc ggccaagccc ctggaggtgc tgttgctgga     1320

gaagaaccgc tcgctgcagt ccgagaacgc cgcgctgcgc atctccaaca gcgacctgag     1380

cggacgctgt gcggagctgc aagtccgtat cactgaggct gtggccacag ccactgagca     1440

gagagagctg atcgcccgcc tggagcagga cctgagcatc attcagtcca tccagcggcc     1500

cgatgccgag ggtgccgctg agcaccgcct ggagaagatc ccagagccca tcaaagaggc     1560

cactgcccta ttctacggac ctgcagcacc agccagcggt gccctcccag agggccaggt     1620

ggattcactg ctttccatca tctccagcca gagggagcgc ttccgtgccc ggaaccagga     1680

gcttgaggcc gagaaccgcc tggcccagca caccctccag gccctgcaga gtgagctgga     1740

cagcctgcgc gccgacaaca tcaagctctt tgagaagatc aagttcctgc agagctaccc     1800

tggccggggc agcggcagtg atgacacgga gctgcggtac tcgtcccagt acgaggagcg     1860

cctggacccc ttctcctcct tcagcaagcg ggagcggcag aggaagtacc tgagcttgag     1920

tccctgggac aaggccaccc tcagcatggg gcgtctggtt ctctccaaca agatggcgcg     1980

caccatcggc ttcttctaca cactgttcct gcactgcctg gtcttcctgg tgctctacaa     2040

gctggcatgg agcgagagca tggagaggga ctgtgccacc ttctgcgcca agaagttcgc     2100

tgaccacctg cacaagttcc acgagaatga caacggggct gcggctggtg acttgtggca     2160

gtgatacccc ggggcctccc ccgtgacagt gacggctgcg cctccacccc gactgctcag     2220

tgcatctaat cacttagact cccctgaaga atcccccatg gaaactgccc ttatccgctg     2280

tccagcagct gccagaggcc ccaggtcacc tcgggtcccc ttgaaagaat gtctcggtca     2340

catcaggccc gctaggtcca gagagcgagc ccccaatgcc cggccaggct aagccgcaga     2400

gaccctctca gcccccacct caggttaggg ctctgcccgc agcctgacct ctagccctgg     2460

tggcagaggt ccctcagctg cgaggctaat tgggtgacca ccgattccag ctgcggttaa     2520

tccagcttgg gcctgtctgc actgcgatcc tcttgggctc tcctaggatc cccccatgcc     2580

ccgtaagagg tggaagacgc ttccttccag gacagcaggc tttgagtcca gcacccccag     2640

cctgcctttg ccaccagccc caccctgcag agtatatgag gcttgacaga gtctgccccc     2700

tcccccactg caccccaaga gagagagccc cagccagcgg aacagtttct attaccccct     2760

ccctgccccc agacccatgt gatttctgct ttcttcttta gcaagatatt ctggtttcta     2820

gataaggaag agtctctaat gagcccccga gccccagtct cttcagactc atggattggt     2880

atgaggggtc tgaacgtctc ctagccaatc agaactggct gtggaccacc ctagcacggc     2940

cacctctcag ggccactggc aggccttcct gagttagatt tgtagttgca tatttagctt     3000

tgcacatttg aaataaacca cggttgcagc caaaaaaaa                            3039


<210>  314
<211>  3033
<212>  DNA
<213>  homo sapiens

<400>  314
ctcggtggcg gcggcggcgg ccggctccag gccgggtttt ggcgccgccc gcctgctgcc       60

tcctggcggc tcctgaactc cagccccctc tctatcagcc gctcactccg tctcaatatg      120

tctcaagatg gcggccaatg tgggatcgat gtttcaatat tggaagcgct ttgatttaca      180

gcagctgcag agagaactcg atgccaccgc aacggtattg gcgaaccggc aggatgaaag      240

tgagcagtcc agaaagcggc ttatcgaaca gagccgggag ttcaagaaga acactccaga      300

ggatttgcgc aagcaggtag cgccgctgct gaagagtttc caaggagaga ttgatgcact      360

gagtaaaaga agcaaggaag ctgaagcagc tttcttgaat gtctacaaaa gattgattga      420

cgtcccagat cccgtaccag ctttggatct cggacagcaa ctccagctca aagtgcagcg      480

cctgcacgat attgaaacag agaaccagaa acttagggaa actctggaag aatacaacaa      540

ggaatttgct gaagtgaaaa atcaagaggt tacgataaaa gcacttaaag agaaaatccg      600

agaatatgaa cagacactga agaaccaagc cgaaaccata gctcttgaga aggaacagaa      660

gttacagaat gactttgcag aaaaggagag aaagctgcag gagacacaga tgtccaccac      720

ctcaaagctg gaggaagctg agcataaggt tcagagccta caaacagccc tggaaaaaac      780

tcgaacagaa ttatttgacc tgaaaaccaa atacgatgaa gaaactactg caaaggccga      840

cgagattgaa atgatcatga cggaccttga aagggcaaac cagagggcag aggtggctca      900

gagagaggcg gagaccttaa gggaacagct ctcatcggcc aatcactccc tccagctggc      960

ctcacagatc cagaaggcac cagacgtggc catagaggtg ctgacccgct ccagcctaga     1020

agttgagttg gccgccaagg agcgggagat cgcacagctg gtggaggacg tgcagagact     1080

ccaggccagc ctcaccaagc tgcgggagaa ttcggccagc cagatctcac agcttgagca     1140

gcagctgagc gccaaaaaca gcacactcaa acaactggaa gaaaaactca aaggccaggc     1200

tgactatgaa gaggtgaaga aagagctgaa cattctgaag tccatggagt ttgcaccgtc     1260

cgagggcgct gggacacagg atgcggccaa gcccctggag gtgctgttgc tggagaagaa     1320

ccgctcgctg cagtccgaga acgccgcgct gcgcatctcc aacagcgacc tgagcggacg     1380

ctgtgcggag ctgcaagtcc gtatcactga ggctgtggcc acagccactg agcagagaga     1440

gctgatcgcc cgcctggagc aggacctgag catcattcag tccatccagc ggcccgatgc     1500

cgagggtgcc gctgagcacc gcctggagaa gatcccagag cccatcaaag aggccactgc     1560

cctattctac ggacctgcag caccagccag cggtgccctc ccagagggcc aggtggattc     1620

actgctttcc atcatctcca gccagaggga gcgcttccgt gcccggaacc aggagcttga     1680

ggccgagaac cgcctggccc agcacaccct ccaggccctg cagagtgagc tggacagcct     1740

gcgcgccgac aacatcaagc tctttgagaa gatcaagttc ctgcagagct accctggccg     1800

gggcagcggc agtgatgaca cggagctgcg gtactcgtcc cagtacgagg agcgcctgga     1860

ccccttctcc tccttcagca agcgggagcg gcagaggaag tacctgagct tgagtccctg     1920

ggacaaggcc accctcagca tggggcgtct ggttctctcc aacaagatgg cgcgcaccat     1980

cggcttcttc tacacactgt tcctgcactg cctggtcttc ctggtgctct acaagctggc     2040

atggagcgag agcatggaga gggactgtgc caccttctgc gccaagaagt tcgctgacca     2100

cctgcacaag ttccacgaga atgacaacgg ggctgcggct ggtgacttgt ggcagtgata     2160

ccccggggcc tcccccgtga cagtgacggc tgcgcctcca ccccgactgc tcagtgcatc     2220

taatcactta gactcccctg aagaatcccc catggaaact gcccttatcc gctgtccagc     2280

agctgccaga ggccccaggt cacctcgggt ccccttgaaa gaatgtctcg gtcacatcag     2340

gcccgctagg tccagagagc gagcccccaa tgcccggcca ggctaagccg cagagaccct     2400

ctcagccccc acctcaggtt agggctctgc ccgcagcctg acctctagcc ctggtggcag     2460

aggtccctca gctgcgaggc taattgggtg accaccgatt ccagctgcgg ttaatccagc     2520

ttgggcctgt ctgcactgcg atcctcttgg gctctcctag gatcccccca tgccccgtaa     2580

gaggtggaag acgcttcctt ccaggacagc aggctttgag tccagcaccc ccagcctgcc     2640

tttgccacca gccccaccct gcagagtata tgaggcttga cagagtctgc cccctccccc     2700

actgcacccc aagagagaga gccccagcca gcggaacagt ttctattacc ccctccctgc     2760

ccccagaccc atgtgatttc tgctttcttc tttagcaaga tattctggtt tctagataag     2820

gaagagtctc taatgagccc ccgagcccca gtctcttcag actcatggat tggtatgagg     2880

ggtctgaacg tctcctagcc aatcagaact ggctgtggac caccctagca cggccacctc     2940

tcagggccac tggcaggcct tcctgagtta gatttgtagt tgcatattta gctttgcaca     3000

tttgaaataa accacggttg cagccaaaaa aaa                                  3033


<210>  315
<211>  4129
<212>  DNA
<213>  homo sapiens

<400>  315
gtgctcgtgg ggagctggcc gagtggaaaa cgtccacatt gacccaaccg cagtgaaggg       60

agagcgcctc cagtggtgtg gtgcgtggag aaatgggaag gagagagttc tgatgagacc      120

ctttttgctc ttcctgctgc atctgagcct gtgatacgct cctctgcaga aaatatggac      180

ttgaaggagc agccaggtaa cactatttcg gctggtcaag aggatttccc atctgtcctg      240

cttgaaactg ctgcttctct tccttctctg tctcctctct cagccgcttc tttcaaagaa      300

catgaatacc ttggtaattt gtcaacagta ttacccactg aaggaacact tcaagaaaat      360

gtcagtgaag cttctaaaga ggtctcagag aaggcaaaaa ctctactcat agatagagat      420

ttaacagagt tttcagaatt agaatactca gaaatgggat catcgttcag tgtctctcca      480

aaagcagaat ctgccgtaat agtagcaaat cctagggaag aaataatcgt gaaaaataaa      540

gatgaagaag agaagttagt tagtaataac atccttcata atcaacaaga gttacctaca      600

gctcttacta aattggttaa agaggatgaa gttgtgtctt cagaaaaagc aaaagacagt      660

tttaatgaaa agagagttgc agtggaagct cctatgaggg aggaatatgc agacttcaaa      720

ccatttgagc gagtatggga agtgaaagat agtaaggaag atagtgatat gttggctgct      780

ggaggtaaaa tcgagagcaa cttggaaagt aaagtggata aaaaatgttt tgcagatagc      840

cttgagcaaa ctaatcacga aaaagatagt gagagtagta atgatgatac ttctttcccc      900

agtacgccag aaggtataaa ggatcgttca ggagcatata tcacatgtgc tccctttaac      960

ccagcagcaa ctgagagcat tgcaacaaac atttttcctt tgttaggaga tcctacttca     1020

gaaaataaga ccgatgaaaa aaaaatagaa gaaaagaagg cccaaatagt aacagagaag     1080

aatactagca ccaaaacatc aaaccctttt cttgtagcag cacaggattc tgagacagat     1140

tatgtcacaa cagataattt aacaaaggtg actgaggaag tcgtggcaaa catgcctgaa     1200

ggcctgactc cagatttagt acaggaagca tgtgaaagtg aattgaatga agttactggt     1260

acaaagattg cttatgaaac aaaaatggac ttggttcaaa catcagaagt tatgcaagag     1320

tcactctatc ctgcagcaca gctttgccca tcatttgaag agtcagaagc tactccttca     1380

ccagttttgc ctgacattgt tatggaagca ccattgaatt ctgcagttcc tagtgctggt     1440

gcttccgtga tacagcccag ctcatcacca ttagaagctt cttcagttaa ttatgaaagc     1500

ataaaacatg agcctgaaaa ccccccacca tatgaagagg ccatgagtgt atcactaaaa     1560

aaagtatcag gaataaagga agaaattaaa gagcctgaaa atattaatgc agctcttcaa     1620

gaaacagaag ctccttatat atctattgca tgtgatttaa ttaaagaaac aaagctttct     1680

gctgaaccag ctccggattt ctctgattat tcagaaatgg caaaagttga acagccagtg     1740

cctgatcatt ctgagctagt tgaagattcc tcacctgatt ctgaaccagt tgacttattt     1800

agtgatgatt caatacctga cgttccacaa aaacaagatg aaactgtgat gcttgtgaaa     1860

gaaagtctca ctgagacttc atttgagtca atgatagaat atgaaaataa ggaaaaactc     1920

agtgctttgc cacctgaggg aggaaagcca tatttggaat cttttaagct cagtttagat     1980

aacacaaaag ataccctgtt acctgatgaa gtttcaacat tgagcaaaaa ggagaaaatt     2040

cctttgcaga tggaggagct cagtactgca gtttattcaa atgatgactt atttatttct     2100

aaggaagcac agataagaga aactgaaacg ttttcagatt catctccaat tgaaattata     2160

gatgagttcc ctacattgat cagttctaaa actgattcat tttctaaatt agccagggaa     2220

tatactgacc tagaagtatc ccacaaaagt gaaattgcta atgccccgga tggagctggg     2280

tcattgcctt gcacagaatt gccccatgac ctttctttga agaacataca acccaaagtt     2340

gaagagaaaa tcagtttctc agatgacttt tctaaaaatg ggtctgctac atcaaaggtg     2400

ctcttattgc ctccagatgt ttctgctttg gccactcaag cagagataga gagcatagtt     2460

aaacccaaag ttcttgtgaa agaagctgag aaaaaacttc cttccgatac agaaaaagag     2520

gacagatcac catctgctat attttcagca gagctgagta aaacttcagt tgttgacctc     2580

ctgtactgga gagacattaa gaagactgga gtggtgtttg gtgccagcct attcctgctg     2640

ctttcattga cagtattcag cattgtgagc gtaacagcct acattgcctt ggccctgctc     2700

tctgtgacca tcagctttag gatatacaag ggtgtgatcc aagctatcca gaaatcagat     2760

gaaggccacc cattcagggc atatctggaa tctgaagttg ctatatctga ggagttggtt     2820

cagaagtaca gtaattctgc tcttggtcat gtgaactgca cgataaagga actcaggcgc     2880

ctcttcttag ttgatgattt agttgattct ctgaagtttg cagtgttgat gtgggtattt     2940

acctatgttg gtgccttgtt taatggtctg acactactga ttttggctct catttcactc     3000

ttcagtgttc ctgttattta tgaacggcat caggcacaga tagatcatta tctaggactt     3060

gcaaataaga atgttaaaga tgctatggct aaaatccaag caaaaatccc tggattgaag     3120

cgcaaagctg aatgaaaacg cccaaaataa ttagtaggag ttcatcttta aaggggatat     3180

tcatttgatt atacggggga gggtcaggga agaacgaacc ttgacgttgc agtgcagttt     3240

cacagatcgt tgttagatct ttatttttag ccatgcactg ttgtgaggaa aaattacctg     3300

tcttgactgc catgtgttca tcatcttaag tattgtaagc tgctatgtat ggatttaaac     3360

cgtaatcata tctttttcct atctatctga ggcactggtg gaataaaaaa cctgtatatt     3420

ttactttgtt gcagatagtc ttgccgcatc ttggcaagtt gcagagatgg tggagctaga     3480

aaaaaaaaaa aaaaagccct tttcagtttg tgcactgtgt atggtccgtg tagattgatg     3540

cagattttct gaaatgaaat gtttgtttag acgagatcat accggtaaag caggaatgac     3600

aaagcttgct tttctggtat gttctaggtg tattgtgact tttactgtta tattaattgc     3660

caatataagt aaatatagat tatatatgta tagtgtttca caaagcttag acctttacct     3720

tccagccacc ccacagtgct tgatatttca gagtcagtca ttggttatac atgtgtagtt     3780

ccaaagcaca taagctagaa gaagaaatat ttctaggagc actaccatct gttttcaaca     3840

tgaaatgcca cacacataga actccaacat caatttcatt gcacagactg actgtagtta     3900

attttgtcac agaatctatg gactgaatct aatgcttcca aaaatgttgt ttgtttgcaa     3960

atatcaaaca ttgttatgca agaaattatt aattacaaaa tgaagattta taccattgtg     4020

gtttaagctg tactgaacta aatctgtgga atgcattgtg aactgtaaaa gcaaagtatc     4080

aataaagctt atagacttaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                 4129


<210>  316
<211>  2742
<212>  DNA
<213>  homo sapiens

<400>  316
gtaactctac ggcctagcaa ccgttgccaa ggagctcgac tctgggagcg gtctagagcc       60

cgggcgcctc ctggggggtg gggaaacggt ttcgtgagga gaatttgagt taaaattata      120

agacctaatt atgagtgatc aaattaaatt cattatggac agtctcaata aggagccctt      180

taggaagaac tataatttaa tcacgtttga ttccttggag ccaatgcaac tattacaagt      240

tctcagtgat gttctggctg agattgaccc aaagcaactt gtggatatca gagaggagat      300

gccagagcag acagccaaac gaatgttgag ccttcttggt attcttaagt acaaaccttc      360

aggaaatgcc acagatatga gtacttttcg tcagggtttg gtgattggaa gtaaacctgt      420

aatttaccca gtgctccact ggcttcttca gaggactaat gaactgaaga aaagagcata      480

tttagctcgt tttttaataa aacttgaggt accaagtgag tttcttcagg atgaaactgt      540

ggctgacacc aataaacagt atgaagagtt aatggaagcc tttaaaactt tgcataaaga      600

atatgagcag ctcaagatat ctggattttc tacagcagaa ataagaaagg atatcagtgc      660

aatggaagaa gaaaaggatc agctcattaa gagagttgaa catttgaaga aaagggttga      720

gacagctcag aatcatcaat ggatgcttaa aatagcaagg caacttcgag ttgaaaaaga      780

gagagaagaa tatcttgcac aacagaaaca ggaacaaaag aatcagctat ttcatgcagt      840

gcaaagattg caaagagtac aaaaccagct gaaaagcatg cgccaagctg cagcagatgc      900

aaagcctgaa agtttaatga agaggctaga ggaggagata aaatttaatt tatatatggt      960

aactgaaaaa tttcctaaag aattagaaaa taagaaaaag gaattacatt ttttacaaaa     1020

agtagtttca gagccagcta tgggccattc tgatcttctt gaacttgaat ctaaaataaa     1080

tgaaataaac acagaaatta accagttgat tgaaaagaaa atgatgagaa atgagcccat     1140

tgaaggcaaa ctctcactgt ataggcaaca ggcatctatc atttcccgta aaaaagaagc     1200

caaagctgag gaacttcagg aggccaagga gaagttagcc agcctagaga gagaagcatc     1260

agtaaagaga aatcagaccc gtgaatttga tggtactgaa gttttaaagg gagatgagtt     1320

caaacgatat gtcaataaac ttcgaagcaa gagtacagtt ttcaaaaaga agcatcagat     1380

aatagctgaa cttaaagctg aattcggtct tttgcagagg actgaagaac ttcttaagca     1440

acgtcatgaa aatattcaac aacaactgca aactatggag gagaaaaagg gtatatctgg     1500

atatagttac acccaagaag agctagaaag agtatctgca ctgaagagtg aagttgatga     1560

aatgaaagga cgaacattgg atgatatgtc tgaaatggtg aaaaaactgt attcattggt     1620

atctgaaaag aagtcagctc ttgcctcagt tataaaagag ctacgacagt tgcgtcaaaa     1680

atatcaagaa ctgacccagg agtgtgatga aaagaaatcc cagtatgata gctgtgcagc     1740

aggcctcgaa agcaatcggt ccaaattaga acaggaagtt agaagactcc gtgaagaatg     1800

tcttcaagaa gaaagtagat accattatac aaattgtatg attaagaacc tagaagttca     1860

acttcgtcgt gctactgatg agatgaaggc atatatctct tctgatcaac aagaaaaaag     1920

aaaggcaatt agggaacagt ataccaaaaa tactgctgaa caagaaaacc ttggaaagaa     1980

acttcgggaa aaacaaaaag ttatacgaga aagtcatggt ccaaatatga aacaagcaaa     2040

aatgtggcgt gatttggaac aattaatgga atgtaagaaa cagtgctttc tgaaacaaca     2100

aagccaaact tccattggtc aggtaattca ggagggtggg gaggaccggc taatactgtg     2160

aattcttgtg tcatcgtttg gggttttact tgataccact agctataagc ctaatctcat     2220

aatgtatttc ttttttgaaa ctgatttgta tagcattttg ttttcagaag agccattctt     2280

tattaagttt tcatagaaaa taatgttaag gtagatttag tttgaatgtt ttttcatatg     2340

aaaaagaggc ttttattctt ttccatagtt tagacatcac tggcgtcttc tgagttttat     2400

gagacaggaa actaagttta ctatctgtaa atgtaaacat atgtccatta agaaacatgt     2460

agtttttttt tagaatgtaa taacccagtg gcttactgtt tttcttaatc tcttttaaaa     2520

aaactttaga agaatctttt aggaactaat atctcttgtt ctgaagaaac atttatctga     2580

cgttcagcag ttcctacagt tttacttcag tttatttttc ttctgtaaaa tgcaagaaaa     2640

tttaatattt tgactaacat gtcttttctg tttgtatcat ttaaaggcaa ataaacttgg     2700

tacgtatttc atatctattt aaaaaatgta aaaaaaaaaa aa                        2742


<210>  317
<211>  3160
<212>  DNA
<213>  homo sapiens

<400>  317
gtaactctac ggcctagcaa ccgttgccaa ggagctcgac tctgggagcg gtctagagcc       60

cgggcgcctc ctggggggtg gggaaacggt ttcgtgagga gaatttgagg taacctcgcc      120

aactcgcggt cggaagctcc tctgaacccc gaaataggag agagctcccg tcctctctcg      180

gtcctgatgc agcacctcgc aagtggaagg ggtcgtcgcg gttaagcccc cggatagggg      240

aatcgggccc cttctgggat tcgagcggat ccaggccgct ccctggaggg atgaactgtc      300

gaggggccca gggcagcccc cgctagaggc ccggtcgggt gtggggtccc ctgtcccctg      360

tcccgagccc ggggaggggg acactatttc tggtactccc aggaggctgc gggtcgatgc      420

tcgtgccagc ctgggaccca ggcagcacgg tttctctccc aaattgtgcc agagaacacg      480

cacgtcctgg ttttcattgt tccccgcctc ctgcgactcg tttgtggtta aaattataag      540

acctaattat gagtgatcaa attaaattca ttatggacag tctcaataag gagcccttta      600

ggaagaacta taatttaatc acgtttgatt ccttggagcc aatgcaacta ttacaagttc      660

tcagtgatgt tctggctgag attgacccaa agcaacttgt ggatatcaga gaggagatgc      720

cagagcagac agccaaacga atgttgagcc ttcttggtat tcttaagtac aaaccttcag      780

gaaatgccac agatatgagt acttttcgtc agggtttggt gattggaagt aaacctgtaa      840

tttacccagt gctccactgg cttcttcaga ggactaatga actgaagaaa agagcatatt      900

tagctcgttt tttaataaaa cttgaggtac caagtgagtt tcttcaggat gaaactgtgg      960

ctgacaccaa taaacagtat gaagagttaa tggaagcctt taaaactttg cataaagaat     1020

atgagcagct caagatatct ggattttcta cagcagaaat aagaaaggat atcagtgcaa     1080

tggaagaaga aaaggatcag ctcattaaga gagttgaaca tttgaagaaa agggttgaga     1140

cagctcagaa tcatcaatgg atgcttaaaa tagcaaggca acttcgagtt gaaaaagaga     1200

gagaagaata tcttgcacaa cagaaacagg aacaaaagaa tcagctattt catgcagtgc     1260

aaagattgca aagagtacaa aaccagctga aaagcatgcg ccaagctgca gcagatgcaa     1320

agcctgaaag tttaatgaag aggctagagg aggagataaa atttaattta tatatggtaa     1380

ctgaaaaatt tcctaaagaa ttagaaaata agaaaaagga attacatttt ttacaaaaag     1440

tagtttcaga gccagctatg ggccattctg atcttcttga acttgaatct aaaataaatg     1500

aaataaacac agaaattaac cagttgattg aaaagaaaat gatgagaaat gagcccattg     1560

aaggcaaact ctcactgtat aggcaacagg catctatcat ttcccgtaaa aaagaagcca     1620

aagctgagga acttcaggag gccaaggaga agttagccag cctagagaga gaagcatcag     1680

taaagagaaa tcagacccgt gaatttgatg gtactgaagt tttaaaggga gatgagttca     1740

aacgatatgt caataaactt cgaagcaaga gtacagtttt caaaaagaag catcagataa     1800

tagctgaact taaagctgaa ttcggtcttt tgcagaggac tgaagaactt cttaagcaac     1860

gtcatgaaaa tattcaacaa caactgcaaa ctatggagga gaaaaagggt atatctggat     1920

atagttacac ccaagaagag ctagaaagag tatctgcact gaagagtgaa gttgatgaaa     1980

tgaaaggacg aacattggat gatatgtctg aaatggtgaa aaaactgtat tcattggtat     2040

ctgaaaagaa gtcagctctt gcctcagtta taaaagagct acgacagttg cgtcaaaaat     2100

atcaagaact gacccaggag tgtgatgaaa agaaatccca gtatgatagc tgtgcagcag     2160

gcctcgaaag caatcggtcc aaattagaac aggaagttag aagactccgt gaagaatgtc     2220

ttcaagaaga aagtagatac cattatacaa attgtatgat taagaaccta gaagttcaac     2280

ttcgtcgtgc tactgatgag atgaaggcat atatctcttc tgatcaacaa gaaaaaagaa     2340

aggcaattag ggaacagtat accaaaaata ctgctgaaca agaaaacctt ggaaagaaac     2400

ttcgggaaaa acaaaaagtt atacgagaaa gtcatggtcc aaatatgaaa caagcaaaaa     2460

tgtggcgtga tttggaacaa ttaatggaat gtaagaaaca gtgctttctg aaacaacaaa     2520

gccaaacttc cattggtcag gtaattcagg agggtgggga ggaccggcta atactgtgaa     2580

ttcttgtgtc atcgtttggg gttttacttg ataccactag ctataagcct aatctcataa     2640

tgtatttctt ttttgaaact gatttgtata gcattttgtt ttcagaagag ccattcttta     2700

ttaagttttc atagaaaata atgttaaggt agatttagtt tgaatgtttt ttcatatgaa     2760

aaagaggctt ttattctttt ccatagttta gacatcactg gcgtcttctg agttttatga     2820

gacaggaaac taagtttact atctgtaaat gtaaacatat gtccattaag aaacatgtag     2880

ttttttttta gaatgtaata acccagtggc ttactgtttt tcttaatctc ttttaaaaaa     2940

actttagaag aatcttttag gaactaatat ctcttgttct gaagaaacat ttatctgacg     3000

ttcagcagtt cctacagttt tacttcagtt tatttttctt ctgtaaaatg caagaaaatt     3060

taatattttg actaacatgt cttttctgtt tgtatcattt aaaggcaaat aaacttggta     3120

cgtatttcat atctatttaa aaaatgtaaa aaaaaaaaaa                           3160


<210>  318
<211>  2324
<212>  DNA
<213>  homo sapiens

<400>  318
gtaactctac ggcctagcaa ccgttgccaa ggagctcgac tctgggagcg gtctagagcc       60

cgggcgcctc ctggggggtg gggaaacggt ttcgtgagga gaatttgagg taacctcgcc      120

aactcgcggt cggaagctcc tctgaacccc gaaataggag agagctcccg tcctctctcg      180

gtcctgatgc agcacctcgc aagtggaagg ggtcgtcgcg gttaagcccc cggatagggg      240

aatcgggccc cttctgggat tcgagcggat ccaggccgct ccctggaggg atgaactgtc      300

gaggggccca gggcagcccc cgctagaggc ccggtcgggt gtggggtccc ctgtcccctg      360

tcccgagccc ggggaggggg acactatttc tggtactccc aggaggctgc gggtcgatgc      420

tcgtgccagc ctgggaccca ggcagcacgg tttctctccc aaattgtgcc agagaacacg      480

cacgtcctgg ttttcattgt tccccgcctc ctgcgactcg tttgtggtta aaattataag      540

acctaattat gagtgatcaa attaaattca ttatggacag tctcaataag gagcccttta      600

ggaagaacta taatttaatc acgtttgatt ccttggagcc aatgcaacta ttacaagttc      660

tcagtgatgt tctggctgag attgacccaa agcaacttgt ggatatcaga gaggagatgc      720

cagagcagac agccaaacga atgttgagcc ttcttggtat tcttaagtac aaaccttcag      780

gaaatgccac agatatgagt acttttcgtc agggtttggt gattggaagt aaacctgtaa      840

tttacccagt gctccactgg cttcttcaga ggactaatga actgaagaaa agagcatatt      900

tagctcgttt tttaataaaa cttgaggtac caagtgagtt tcttcaggat gaaactgtgg      960

ctgacaccaa taaacagtat gaagagttaa tggaagcctt taaaactttg cataaagaat     1020

atgagcagct caagatatct ggattttcta cagcagaaat aagaaaggat atcagtgcaa     1080

tggaagaaga aaaggatcag ctcattaaga gagttgaaca tttgaagaaa agggttgaga     1140

cagctcagaa tcatcaatgg atgcttaaaa tagcaaggca acttcgagtt gaaaaagaga     1200

gagaagaata tcttgcacaa cagaaacagg aacaaaagaa tcagctattt catgcagtgc     1260

aaagattgca aagagtacaa aaccagctga aaagcatgcg ccaagctgca gcagatgcaa     1320

agcctgaaag tttaatgaag aggctagagg aggagataaa atttaattta tatatggtaa     1380

ctgaaaaatt tcctaaagaa ttagaaaata agaaaaagga attacatttt ttacaaaaag     1440

tagtttcaga gccagctatg ggccattctg atcttcttga acttgaatct aaaataaatg     1500

aaataaacac agaaattaac cagttgattg aaaagaaaat gatgagaaat gagcccattg     1560

aaggcaaact ctcactgtat aggcaacagg catctatcat ttcccgtaaa aaagaagcca     1620

aagctgagga acttcaggag gccaaggaga agttagccag cctagagaga gaagcatcag     1680

taaagagaaa tcagacccgt gaatttgatg gtactgaagt tttaaaggga gatgagagac     1740

aggatctcac tctgtcaccc aggctggagt gcggtggtgt gatcatggct tactgcagcc     1800

tgaaactcct aggctcaagt gatcctccta cctcagcctc ctgagaagct cggactacag     1860

gcacgagcca ccatgcccag ctaattttct ttttttgttt tgttttgtag agatgtggtc     1920

tcactatgtt tcccaggctg gtcttaaact cccggcctca agcagtcctc ccacttcggc     1980

ctcctgaagt gttaggatta caggcgtgag cctgcgcctg gctgtaatta ctatacccag     2040

tttttacaga taaaggatct gagacatgca gaggttttaa gctgacttgc ctgacacccc     2100

attgctagta agtagtagaa ccaggagttg gatttagcag tctggctgta gagtcatcaa     2160

tagtttgcac atgacagaaa gctggaagaa atagtcaacc tgaaacacat gatggaatta     2220

taattcagaa tcatcttggt agataggggc actgtgctta aacaaaatgc cattaatggg     2280

attataataa atataatgtg gtagaattca aaaaaaaaaa aaaa                      2324


<210>  319
<211>  4161
<212>  DNA
<213>  homo sapiens

<400>  319
gggagcgccg gggaggcggg cggaggcggg cggaggcggg gggcggggag cccgaggggt       60

ggaagccggc ggcggccgag cggggtcagt tctctgtagt gtttgccaat gttggagccg      120

tctgcaaagt gtccccggca agaagaggct gcctaccaca aggactttag cttacttttt      180

aaagattgaa gaaaaaaaag aagacagaaa aagaagaact caaagataca caaagtaatt      240

tgaaccaagg ctcagaagtt tttggagccg tgagggatac agcagtttgg tcaatattgt      300

cttaacatgc ttcaaataaa tcagatgttc tcagtgcagc tgagtcttgg tgagcagaca      360

tgggaatccg aaggcagcag tataaagaag gctcagcagg ctgttgccaa taaagctttg      420

actgaatcta cgcttcccaa accagttcag aagccaccca aaagtaatgt taacaataac      480

ccaggcagta taactccaac tgtggaactg aatgggcttg ctatgaaaag gggagagcct      540

gccatctaca ggccattaga tccaaagcca ttcccaaatt atagagctaa ttacaacttt      600

cggggcatgt acaatcagag gtatcattgc ccagtgccta agatctttta tgttcagctc      660

actgtaggaa ataatgaatt ttttggggaa ggaaagactc gacaagctgc tagacacaat      720

gctgcaatga aagccctcca agcactgcag aatgaaccta ttccagaaag atctcctcag      780

aatggtgaat caggaaagga tgtggatgat gacaaagatg caaataagtc tgagatcagc      840

ttagtgtttg aaattgctct gaagcgaaat atgcctgtca gttttgaggt tattaaagaa      900

agtggaccac cacatatgaa aagctttgtt actcgagtgt cagtaggaga gttctctgca      960

gaaggagaag gaaatagcaa aaaactctcc aagaagcgcg ctgcgaccac cgtcttacag     1020

gagcttaaaa aacttccacc tcttcctgtg gtggaaaagc caaaactatt ttttaaaaaa     1080

cgccctaaaa caatagtaaa ggccggacca gaatatggcc aagggatgaa ccctattagc     1140

cgcctggcgc aaattcaaca ggccaaaaag gaaaaggagc cggattatgt tttgctttca     1200

gaaagaggaa tgcctcgacg tcgagaattt gtgatgcagg tgaaggtagg caatgaagtt     1260

gctacaggaa caggacctaa taaaaagata gccaaaaaaa atgctgcaga agcaatgctg     1320

ttacaacttg gttataaagc atccactaat cttcaggatc aacttgagaa gacaggggaa     1380

aacaaaggat ggagtggtcc aaagcctggg tttcctgaac caacaaataa tactccaaaa     1440

ggaattcttc atttgtctcc tgatgtttat caagagatgg aagccagccg ccacaaagta     1500

atctctggca ctactctagg ctatttgtca cccaaagata tgaaccaacc ttcaagctct     1560

ttcttcagta tatctcccac atcgaatagt tcagctacaa ttgccaggga actccttatg     1620

aatggaacat cttctacagc tgaagccata ggtttaaaag gaagttctcc tactccccct     1680

tgttctccag tacaaccttc aaaacaactg gaatatttag caaggattca aggctttcag     1740

gtatgaatta aaagcaaaaa caaaaaacaa aacaattcat tagcctcaga ttcttcatct     1800

gtatacatca caaggctcat tcttgcctgc tagtatggcc tacatgccac ttacgtttta     1860

agttatttag gaacacaaag gacagacaaa aaagccatat gcacatgcct cattttctct     1920

tatttttgat ctatctagta attcttttgc tgcctgtctc ttctccattt tccttcttct     1980

tttttaagca tttttcatat tcttcactgt cttctatttg gtcttgatta ggtgcatcta     2040

tctcttcgct ctgtcttcca caaacaaaaa ttctgccttc agacatttgg tgttagtatt     2100

tcacactcag ttctcccttt ttttacataa ggattgagtt tctttttatg atgattttac     2160

ctttatagca attttgaatt ttgcattcta ttgctagtat tgattcaggt acaccattaa     2220

gatacaacat tctagaagtc tattacctta ggagttaatt aaacatgata tttgaagaat     2280

aatgaaatgc tttatagttg tttgaggcat aacaatgtgt atttgtttta ctggatcatg     2340

ttttgaactg actagggagg gtagcacctg cctcagatag taccaacaat tctgtttcac     2400

tgggtagtct aaaactagct tatagtttaa cttaacttgt tgtgtatgtg aatttaggga     2460

tggaaacttt ttttccccta tttattcttt gtttccttct gggaaaaaac cccacaaaaa     2520

tcagcactcc tttatggata cattggagct tttgaaagaa ttgtaaactc taggaagggg     2580

aaatatctgt gtcttgattt cttagttgcc ttgaaaatca tgtactgaac tgtaaccgct     2640

aacttgactg gatgaactag tttgcttgtg tgtagagagt gtattgcttc ctcagatttc     2700

actgttttca tctccttttc catcttagtc tttattcctt aagaccaaaa actgtaatat     2760

cctttagaaa tgctctagaa gatctgtatt gtgtagaatg atcatgtatt tataaatatt     2820

ttacaagttt agattataaa atgaaaaaga aggtcatgtg ttttgggggg tattttgcat     2880

gttcggattt ttttttcact tcaccgaacc cttctgattc tttcaaacta ttgccaggta     2940

gttgttagtg tttctaattg gactcttaat atgaacttca agaagctgtt accagttatc     3000

ggctctgtca tctgaaattt taaccactta atttaaagtt acaattttag aatttgtttt     3060

tgttgtttta ccttaagaaa cacaataaat cactgtttaa aaaagatctc aatttatata     3120

aagtactgga aaaaagctaa gtaattttta gttctatcta taatctccgt aggatgaatt     3180

agaaataaat tgtgatgaaa agaaattaac tgcttattta tgaatctaat catttagaaa     3240

tgtctgagag taacactgca ttcttataga aacaaagcac aaattgcatt caagctctga     3300

attgattttt tgcttggagc tgttgttaca gtagctgtaa ttttgctacc agaatgtctt     3360

aattttttaa atttgttttt atttctaagc tcttggcaat gacaataatt ataattttaa     3420

catatcttca ctgtagtcaa catgtagagt ctgcttccct cattattgca ttgctaaggc     3480

ctttttaaaa agcttatgct tacataatat actctttttt atggacacgt tatatgtttc     3540

caaatctgtg tattgtgatt tttacatact aatgaatata aacaggtgat tttaaaatat     3600

tactgtgctt ctttggttga atgagctggt attgatgtaa aatactctgt cattgatgga     3660

ccactacctg cagctaagca gtgagcagaa tctccgggaa atgacttagt ctggccacat     3720

gcatagccca tcttcataat gtcgcagcag aaggttcttt gtggttaaaa gttttaaagc     3780

ctatttcttt ataggtaacc ctctcaggta tatttacctg gtagaaaaac atgtagattg     3840

tttctattac ttaaatgttt taattggact gtagtttaga aattacagga ccagcttgtt     3900

acagattata cactattctg ttacttttat ttctgaaact taaaaacaat aaattctttt     3960

tctgtgtttc taggttagaa cttttttatt ttattgcaca ctgaacagat actgttgctt     4020

attgaatatt gtgtaaaccc ttctttggct ttccttgccc attgcaattt gatttaagcc     4080

tactagagcc attgtatgtg acagctatat tgtattacaa agtaaaaata tatgagtgta     4140

ttgaaaacaa aaaaaaaaaa a                                               4161


<210>  320
<211>  1114
<212>  DNA
<213>  homo sapiens

<400>  320
cgagccgcga agattgtttt tgtcccgccg aaatcgagca aagcacgctg gaacttgtag       60

tccttgaggc cccttcccta ggtccttcga gctactccgt ctggccccgc cttttctctg      120

ctctcctgaa cctttaggct tgtctcggcc catttgaaga ccaggaagtt gatcaatccc      180

gaggctgctg agagacggtg gcgcgattgg gacagtcgcc agggatggct gagcgtgaag      240

atgcagcggg tgtccgggct gctctcctgg acgctgagca gagtcctgtg gctctccggc      300

ctctctgagc cgggagctgc ccggcagccc cggatcatgg aagagaaagc gctagaagtt      360

tatgatttga ttagaactat ccgggaccca gaaaagccca atactttaga agaactggaa      420

gtggtctcgg aaagttgtgt ggaagttcag gagataaatg aagaagaata tctggttatt      480

atcaggttca cgccaacagt acctcattgc tctttggcga ctcttattgg gctgtgctta      540

agagtaaaac ttcagcgatg tttaccattt aaacataagt tggaaatcta catttctgaa      600

ggaacccact caacagaaga agacatcaat aagcagataa atgacaaaga gcgagtggca      660

gctgcaatgg aaaaccccaa cttacgggaa attgtggaac agtgtgtcct tgaacctgac      720

tgatagctgt tttaagagcc actggcctgt aattgtttga tatatttgtt taaactcttt      780

gtataatgtc agagactcat gtttaataca taggtgattt gtacctcaga gtatttttta      840

aaggattctt tccaagcgag atttaattat aaggtagtac ctaatttgtt caatgtataa      900

cattctcagg atttgtaaca cttaaatgat cagacagaat aatattttct agttattatg      960

tgtaagatga gttgctattt ttctgatgct cattctgata caactatttt tcgtgtcaaa     1020

tatctactgt gcccaaatgt actcaattta aatcattact ctgtaaaata aataagcaga     1080

tgattcttat aatgaaaaaa aaaaaaaaaa aaaa                                 1114


<210>  321
<211>  4569
<212>  DNA
<213>  homo sapiens

<400>  321
tcttgttgtt acgggtaacg gaagtgtggc ggcgttgggt tgagcgggct ttttggaagt       60

ttgtggcgga gttctgtgat atgagcaaca atggaccaga agattttatc tctagcagca      120

gaaaaaacag cagacaaact gcaagaattt cttcaaaccc tgagagaagg tgatttgact      180

aatctccttc agaatcaagc agtgaaagga aaagttgctg gagcactcct gagagccatc      240

ttcaaaggtt ccccctgctc tgaggaagct ggaacactta ggagacgtaa gatatacact      300

tgttgtatcc agttggtgga atcgggggat ttgcagaaag aaatagcgtc tgagatcata      360

ggattactga tgctggaggc tcaccatttt ccaggaccat tattggttga attagccaat      420

gagtttatta gtgctgtcag agaaggcagc ctagtgaatg gaaaatcttt ggagttacta      480

cctatcattc tcactgccct ggctacgaaa aaggaaaatc tggcttatgg aaaaggtgta      540

ctgagtgggg aagaatgtaa gaaacagttg attaacaccc tgtgttctgg caggtgggat      600

cagcaatatg taatccaact cacctccatg ttcaaggatg tccctctgac tgcagaagag      660

gtggaatttg tggtggaaaa agcattgagc atgttctcca agatgaatct tcaagaaata      720

ccacctttgg tctatcagct tctggttctc tcctccaagg gaagcagaaa gagtgttttg      780

gaaggaatca tagccttctt cagtgcacta gataagcagc acaatgagga acagagtggt      840

gacgagctat tggatgttgt cactgtgcca tcaggtgaac ttcgtcatgt ggaaggcacc      900

attattctac acattgtgtt tgccatcaaa ttggactatg aactaggcag agaactcgtg      960

aaacacttaa aggtaggaca gcaaggagat tccaataata acttaagtcc cttcagcatt     1020

gctcttcttc tgtctgtaac aagaatacaa agatttcagg accaggtgct tgatctttta     1080

aagacttcgg ttgtaaagag ctttaaggat cttcaactcc tccaaggctc aaaatttctt     1140

cagaatctag ttcctcatag atcttatgtt tcaaccatga tcttggaagt agtgaagaat     1200

agcgttcata gctgggacca tgttactcag ggcctcgtag aacttggttt cattttgatg     1260

gattcatatg ggccaaagaa ggttcttgat ggaaaaacta ttgaaaccag cccaagtctt     1320

tctagaatgc caaaccagca tgcatgtaag ctcggagcta atatcctgtt ggaaactttt     1380

aagatccatg agatgatcag acaagaaatt ttggagcagg tcctcaacag ggttgttacc     1440

agagcatctt ctcccatcag tcatttctta gacctgcttt caaatatcgt catgtatgca     1500

cccttagttc ttcaaagttg ttcttctaaa gtcacagaag cttttgacta tttgtccttt     1560

ctgccccttc agactgtaca aaggctgctt aaggcagtgc agccccttct caaagtcagc     1620

atgtcaatga gagactgctt gatacttgtc cttcggaaag ctatgtttgc caaccagctt     1680

gatgcccgaa aatctgcagt tgctgggttt ttgctgctcc tgaagaactt taaagtttta     1740

ggcagcctgt catcctctca gtgcagtcag tctctcagtg tcagtcaggt tcatgtggat     1800

gttcacagcc attacaattc tgtcgccaat gaaacttttt gccttgagat catggatagt     1860

ttgaggagat gcttaagcca gcaagctgat gttcgactca tgctttatga ggggttttat     1920

gatgttcttc gaaggaactc tcagctggct aattcagtca tgcaaactct gctctcacag     1980

ttaaaacagt tctatgagcc aaaacctgat ctgctgcctc ctctgaaatt agaagcttgt     2040

attctgaccc aaggagataa gatctctcta caagaaccac tggattatct gctgtgttgt     2100

attcagcatt gtttggcctg gtataagaat acagtcatac ccttacagca gggagaggag     2160

gaagaggagg aggaagaggc attctacgaa gacctagatg atatattgga gtccattact     2220

aatagaatga ttaagagtga gctggaagac tttgaactgg ataaatcagc agatttttct     2280

cagagcacca gtattggcat aaaaaataat atctgtgctt ttcttgtgat gggagtttgt     2340

gaggttttaa tagaatacaa tttctccata agtagtttca gtaagaatag gtttgaggac     2400

attctgagct tatttatgtg ttacaaaaaa ctctctgaca ttcttaatga aaaagcgggt     2460

aaagccaaaa ctaaaatggc caacaagaca agtgatagtc ttttgtccat gaaatttgtg     2520

tccagtcttc tcactgctct tttcagagtc ttgctatgga gatacacttc aattcctact     2580

tcagtggaag agtcgggaaa gaaagagaaa ggaaagagca tctcactgct gtgcttggag     2640

ggtttacaga aaatattcag tgctgtgcaa cagttctatc agcccaagat tcagcagttt     2700

ctcagagctc tggatgtcac agataaggaa ggagaagaga gagaagatgc agatgtcagt     2760

gtcactcaga gaacagcatt ccagatccgg caatttcaga ggtccttgtt gaatttactt     2820

agcagtcaag aggaagattt taatagcaaa gaagccctcc tgctagtcac ggttcttacc     2880

agtttgtcca agttactgga gccctcctct cctcagtttg tgcagatgtt atcctggaca     2940

tcaaagattt gcaaggaaaa cagccgggag gatgccttgt tttgcaagag cttgatgaac     3000

ttgctcttca gcctgcatgt ttcgtataag agtcctgtca ttctgctgcg tgacttgtcc     3060

caggatatcc acgggcatct gggagatata gaccaggatg tagaggtgga gaaaacaaac     3120

cactttgcaa tagtgaattt gagaacggct gcccccactg tctgtttact tgttctgagt     3180

caggccgaga aggttctaga agaagtggac tggctaatca ccaagcttaa gggacaagtg     3240

agccaagaaa ccttatcaga agaggcctct tctcaggcaa ccctaccaaa tcagcctgtt     3300

gagaaagcta tcatcatgca actgggaact ctgcttacat ttttccacga gctggtgcag     3360

acagctctgc catcaggcag ctgtgtggac accttgttaa aggacttgtg caaaatgtac     3420

accacactta cagcccttgt cagatattat ctccaggtgt gtcagagctc cggaggaatt     3480

ccaaaaaata tggaaaagct ggtgaagctg tctggttctc atctgacccc cctgtgttat     3540

tctttcattt cttacgtaca gaataagagt aagagcctga actatacggg agagaaaaag     3600

gagaaacctg ctgccgttgc cacagccatg gccagagttc ttcgggaaac caagccaatc     3660

cctaacctca tctttgccat agaacagtat gaaaaatttc tcatccacct ttctaagaag     3720

tccaaggtga acctgatgca gcacatgaag ctcagcacct cacgagactt caagatcaaa     3780

ggaaacatcc tagacatggt tcttcgagag gatggtgaag atgaaaatga agagggcact     3840

gcatcagagc atgggggaca gaacaaagaa ccagccaaga agaaaaggaa aaaataaatg     3900

aaatgcctga gttaatgtga actttggggc ttctgcttca tttttaccca acaagcaaca     3960

atgccccttg tcctgtagtc cacaccgatg ttggcatctt ggttctgaac ccactgaatt     4020

caactgcacc ttcagttaga aggaatcttc ttggcaggtc ctgctactga aaaatggctg     4080

gccttaggca agcccttttg caaaaagcac agctgaaagc ctgagtttgg gagcctgcac     4140

caccccgatg aagctccacg ggagcaaata cagagcctcc aggcagtgct atggtccagg     4200

ctggcttcgt ttttccaagg agcctttggt gagttcaatt atctggtaaa tatccagcgc     4260

ttcacctgaa agatagtgca aattggttag gatgccacct caagaactgt aactgagagc     4320

tcagaagtga gcaaaggagc ttaatgctaa ggtcaaaagg agagtgaaag gttgagaaca     4380

attgccacga acggtaatgt tacatgttag gagggtctgt tttcttttta tataagtgtg     4440

tcttagatat attttaaata gaaaataagc tttctgattt acttgtttgg tatttaaagc     4500

acagtttgtt tttctgtcac ctatagagtg caagaatgca ctctatagaa taaattatct     4560

ttaaacatt                                                             4569


<210>  322
<211>  4749
<212>  DNA
<213>  homo sapiens

<400>  322
tcttgttgtt acgggtaacg gaagtgtggc ggcgttgggt tgagcgggct ttttggaagt       60

ttgtggcgga gttctgtgat atgagcaaca atggaccaga agattttatc tctagcagca      120

gaaaaaacag cagacaaact gcaagaattt cttcaaaccc tgagagaagg tgatttgact      180

aatctccttc agaatcaagc agtgaaagga aaagttgctg gagcactcct gagagccatc      240

ttcaaaggtt ccccctgctc tgaggaagct ggaacactta ggagacgtaa gatatacact      300

tgttgtatcc agttggtgga atcgggggat ttgcagaaag aaatagcgtc tgagatcata      360

ggattactga tgctggaggc tcaccatttt ccaggaccat tattggttga attagccaat      420

gagtttatta gtgctgtcag agaaggcagc ctagtgaatg gaaaatcttt ggagttacta      480

cctatcattc tcactgccct ggctacgaaa aaggaaaatc tggcttatgg aaaaggtgta      540

ctgagtgggg aagaatgtaa gaaacagttg attaacaccc tgtgttctgg caggtgggat      600

cagcaatatg taatccaact cacctccatg ttcaaggatg tccctctgac tgcagaagag      660

gtggaatttg tggtggaaaa agcattgagc atgttctcca agatgaatct tcaagaaata      720

ccacctttgg tctatcagct tctggttctc tcctccaagg gaagcagaaa gagtgttttg      780

gaaggaatca tagccttctt cagtgcacta gataagcagc acaatgagga acagagtggt      840

gacgagctat tggatgttgt cactgtgcca tcaggtgaac ttcgtcatgt ggaaggcacc      900

attattctac acattgtgtt tgccatcaaa ttggactatg aactaggcag agaactcgtg      960

aaacacttaa aggtaggaca gcaaggagat tccaataata acttaagtcc cttcagcatt     1020

gctcttcttc tgtctgtaac aagaatacaa agatttcagg accaggtgct tgatctttta     1080

aagacttcgg ttgtaaagag ctttaaggat cttcaactcc tccaaggctc aaaatttctt     1140

cagaatctag ttcctcatag atcttatgtt tcaaccatga tcttggaagt agtgaagaat     1200

agcgttcata gctgggacca tgttactcag ggcctcgtag aacttggttt cattttgatg     1260

gattcatatg ggccaaagaa ggttcttgat ggaaaaacta ttgaaaccag cccaagtctt     1320

tctagaatgc caaaccagca tgcatgtaag ctcggagcta atatcctgtt ggaaactttt     1380

aagatccatg agatgatcag acaagaaatt ttggagcagg tcctcaacag ggttgttacc     1440

agagcatctt ctcccatcag tcatttctta gacctgcttt caaatatcgt catgtatgca     1500

cccttagttc ttcaaagttg ttcttctaaa gtcacagaag cttttgacta tttgtccttt     1560

ctgccccttc agactgtaca aaggctgctt aaggcagtgc agccccttct caaagtcagc     1620

atgtcaatga gagactgctt gatacttgtc cttcggaaag ctatgtttgc caaccagctt     1680

gatgcccgaa aatctgcagt tgctgggttt ttgctgctcc tgaagaactt taaagtttta     1740

ggcagcctgt catcctctca gtgcagtcag tctctcagtg tcagtcaggt tcatgtggat     1800

gttcacagcc attacaattc tgtcgccaat gaaacttttt gccttgagat catggatagt     1860

ttgaggagat gcttaagcca gcaagctgat gttcgactca tgctttatga ggggttttat     1920

gatgttcttc gaaggaactc tcagctggct aattcagtca tgcaaactct gctctcacag     1980

ttaaaacagt tctatgagcc aaaacctgat ctgctgcctc ctctgaaatt agaagcttgt     2040

attctgaccc aaggagataa gatctctcta caagaaccac tggattatct gctgtgttgt     2100

attcagcatt gtttggcctg gtataagaat acagtcatac ccttacagca gggagaggag     2160

gaagaggagg aggaagaggc attctacgaa gacctagatg atatattgga gtccattact     2220

aatagaatga ttaagagtga gctggaagac tttgaactgg ataaatcagc agatttttct     2280

cagagcacca gtattggcat aaaaaataat atctgtgctt ttcttgtgat gggagtttgt     2340

gaggttttaa tagaatacaa tttctccata agtagtttca gtaagaatag gtttgaggac     2400

attctgagct tatttatgtg ttacaaaaaa ctctctgaca ttcttaatga aaaagcgggt     2460

aaagccaaaa ctaaaatggc caacaagaca agtgatagtc ttttgtccat gaaatttgtg     2520

tccagtcttc tcactgctct tttcagggat agtatccaaa gccaccaaga aagcctttct     2580

gttctcaggt ccagcaatga gtttatgcgc tatgcagtga atgtagctct gcagaaagta     2640

cagcagctaa aggaaacagg gcatgtgagt ggccctgatg gccaaaaccc agaaaagatc     2700

tttcagaacc tctgtgacat aactcgagtc ttgctatgga gatacacttc aattcctact     2760

tcagtggaag agtcgggaaa gaaagagaaa ggaaagagca tctcactgct gtgcttggag     2820

ggtttacaga aaatattcag tgctgtgcaa cagttctatc agcccaagat tcagcagttt     2880

ctcagagctc tggatgtcac agataaggaa ggagaagaga gagaagatgc agatgtcagt     2940

gtcactcaga gaacagcatt ccagatccgg caatttcaga ggtccttgtt gaatttactt     3000

agcagtcaag aggaagattt taatagcaaa gaagccctcc tgctagtcac ggttcttacc     3060

agtttgtcca agttactgga gccctcctct cctcagtttg tgcagatgtt atcctggaca     3120

tcaaagattt gcaaggaaaa cagccgggag gatgccttgt tttgcaagag cttgatgaac     3180

ttgctcttca gcctgcatgt ttcgtataag agtcctgtca ttctgctgcg tgacttgtcc     3240

caggatatcc acgggcatct gggagatata gaccaggatg tagaggtgga gaaaacaaac     3300

cactttgcaa tagtgaattt gagaacggct gcccccactg tctgtttact tgttctgagt     3360

caggccgaga aggttctaga agaagtggac tggctaatca ccaagcttaa gggacaagtg     3420

agccaagaaa ccttatcaga agaggcctct tctcaggcaa ccctaccaaa tcagcctgtt     3480

gagaaagcta tcatcatgca actgggaact ctgcttacat ttttccacga gctggtgcag     3540

acagctctgc catcaggcag ctgtgtggac accttgttaa aggacttgtg caaaatgtac     3600

accacactta cagcccttgt cagatattat ctccaggtgt gtcagagctc cggaggaatt     3660

ccaaaaaata tggaaaagct ggtgaagctg tctggttctc atctgacccc cctgtgttat     3720

tctttcattt cttacgtaca gaataagagt aagagcctga actatacggg agagaaaaag     3780

gagaaacctg ctgccgttgc cacagccatg gccagagttc ttcgggaaac caagccaatc     3840

cctaacctca tctttgccat agaacagtat gaaaaatttc tcatccacct ttctaagaag     3900

tccaaggtga acctgatgca gcacatgaag ctcagcacct cacgagactt caagatcaaa     3960

ggaaacatcc tagacatggt tcttcgagag gatggtgaag atgaaaatga agagggcact     4020

gcatcagagc atgggggaca gaacaaagaa ccagccaaga agaaaaggaa aaaataaatg     4080

aaatgcctga gttaatgtga actttggggc ttctgcttca tttttaccca acaagcaaca     4140

atgccccttg tcctgtagtc cacaccgatg ttggcatctt ggttctgaac ccactgaatt     4200

caactgcacc ttcagttaga aggaatcttc ttggcaggtc ctgctactga aaaatggctg     4260

gccttaggca agcccttttg caaaaagcac agctgaaagc ctgagtttgg gagcctgcac     4320

caccccgatg aagctccacg ggagcaaata cagagcctcc aggcagtgct atggtccagg     4380

ctggcttcgt ttttccaagg agcctttggt gagttcaatt atctggtaaa tatccagcgc     4440

ttcacctgaa agatagtgca aattggttag gatgccacct caagaactgt aactgagagc     4500

tcagaagtga gcaaaggagc ttaatgctaa ggtcaaaagg agagtgaaag gttgagaaca     4560

attgccacga acggtaatgt tacatgttag gagggtctgt tttcttttta tataagtgtg     4620

tcttagatat attttaaata gaaaataagc tttctgattt acttgtttgg tatttaaagc     4680

acagtttgtt tttctgtcac ctatagagtg caagaatgca ctctatagaa taaattatct     4740

ttaaacatt                                                             4749


<210>  323
<211>  5588
<212>  DNA
<213>  homo sapiens

<400>  323
gcggccgcgg cggcgggagg cggcgggagg cgggcggagg aggaggcgga ggaggcggga       60

gctgagctga gtggggcggg cggcggcggg gcccgagccg gagaagatgg cggtgcggaa      120

gaaggacggc ggccccaacg tgaagtacta cgaggccgcg gacaccgtga cccagttcga      180

caacgtgcgg ctgtggctcg gcaagaacta caagaagtat atacaagctg aaccacccac      240

caacaagtcc ctgtctagcc tggttgtaca gttgctacaa tttcaggaag aagtttttgg      300

caaacatgtc agcaatgcac cgctcactaa actgccgatc aaatgtttcc tagatttcaa      360

agcgggaggc tccttgtgcc acattcttgc agctgcctac aaattcaaga gtgaccaggg      420

atggcggcgt tacgatttcc agaatccatc acgcatggac cgcaatgtgg aaatgtttat      480

gaccattgag aagtccttgg tgcagaataa ttgcctgtct cgacctaaca tttttctgtg      540

cccagaaatt gagcccaaac tactagggaa attaaaggac attatcaaga gacaccaggg      600

aacagtcact gaggataaga acaatgcctc ccatgttgtg tatcctgtcc cggggaatct      660

agaagaagag gaatgggtac gaccagtcat gaagagggat aagcaggttc ttctgcactg      720

gggctactat cctgacagtt acgacacgtg gatcccagcg agtgaaattg aggcatctgt      780

ggaagatgct ccaactcctg agaaacctag gaaggttcat gcaaagtgga tcctggacac      840

cgacaccttc aatgaatgga tgaatgagga agactatgaa gtaaatgatg acaaaaaccc      900

tgtctcccgc cgaaagaaga tttcagccaa gacactgaca gatgaggtga acagcccaga      960

ttcagatcga cgggacaaga aggggggaaa ctataagaag aggaagcgct ccccctctcc     1020

ttcaccaacc ccagaagcaa agaagaaaaa tgctaagaaa ggtccctcaa caccttacac     1080

taagtcaaag cgtggccaca gagaagagga gcaagaagac ctgacaaagg acatggacga     1140

gccctcacca gtccccaatg tagaagaggt gacacttccc aaaacagtca acacaaagaa     1200

agactcagag tcggccccag tcaaaggcgg caccatgacc gacctggatg aacaggaaga     1260

tgaaagcatg gagacgacgg gcaaggatga ggatgagaac agtacgggga acaagggaga     1320

gcagaccaag aatccagacc tgcatgagga caatgtgact gaacagaccc accacatcat     1380

cattcccagc tacgctgcct ggtttgacta caatagtgtt catgccattg agcggagggc     1440

tctccccgag ttcttcaacg gcaagaacaa gtccaagact ccagagatct acctggccta     1500

tcgaaacttt atgattgaca cttaccgact gaacccccaa gagtatctta cctctaccgc     1560

ctgccgccga aacctagcgg gtgatgtctg tgccatcatg agggtccatg ccttcctaga     1620

acagtggggt cttattaact accaggtgga tgctgagagt cgaccaaccc caatggggcc     1680

tccgcctacc tctcacttcc atgtcttggc tgacacacca tcagggctgg tgcctctgca     1740

gcccaagaca cctcagcaga cctctgcttc ccaacaaatg ctcaactttc ctgacaaagg     1800

caaagagaaa ccaacagaca tgcaaaactt tgggctgcgc acagacatgt acacaaaaaa     1860

gaatgttccc tccaagagca aggctgcagc cagtgccact cgtgagtgga cagaacagga     1920

aaccctgctt ctcctggagg cactggaaat gtacaaagat gactggaaca aagtgtccga     1980

gcatgtggga agccgcacac aggacgagtg catcttgcat tttcttcgtc ttcccattga     2040

agacccatac ctggaggact cagaggcctc cctaggcccc ctggcctacc aacccatccc     2100

cttcagtcag tcgggcaacc ctgttatgag cactgttgcc ttcctggcct ctgtcgtcga     2160

tccccgagtc gcctctgctg ctgcaaagtc agccctagag gagttctcca aaatgaagga     2220

agaggtaccc acggccttgg tggaggccca tgttcgaaaa gtggaagaag cagccaaagt     2280

aacaggcaag gcggaccctg ccttcggtct ggaaagcagt ggcattgcag gaaccacctc     2340

tgatgagcct gagcggattg aggagagcgg gaatgacgag gctcgggtgg aaggccaggc     2400

cacagatgag aagaaggagc ccaaggaacc ccgagaagga gggggtgcta tagaggagga     2460

agcaaaagag aaaaccagcg aggctcccaa gaaggatgag gagaaaggga aagaaggcga     2520

cagtgagaag gagtccgaga agagtgatgg agacccaata gtcgatcctg agaaggagaa     2580

ggagccaaag gaagggcagg aggaagtgct gaaggaagtg gtggagtctg agggggaaag     2640

gaagacaaag gtggagcggg acattggcga gggcaacctc tccaccgctg ctgccgccgc     2700

cctggccgcc gccgcagtga aagctaagca cttggctgct gttgaggaaa ggaagatcaa     2760

atctttggtg gccctgctgg tggagaccca gatgaaaaag ttggagatca aacttcggca     2820

ctttgaggag ctggagacta tcatggaccg ggagcgagaa gcactggagt atcagaggca     2880

gcagctcctg gccgacagac aagccttcca catggagcag ctgaagtatg cggagatgag     2940

ggctcggcag cagcacttcc aacagatgca ccaacagcag cagcagccac caccagccct     3000

gcccccaggc tcccagccta tccccccaac aggggctgct gggccacccg cagtccatgg     3060

cttggctgtg gctccagcct ctgtagtccc tgctcctgct ggcagtgggg cccctccagg     3120

aagtttgggc ccttctgaac agattgggca ggcagggtca actgcagggc cacagcagca     3180

gcaaccagct ggagcccccc agcctggggc agtcccacca ggggttcccc cccctggacc     3240

ccatggcccc tcaccgttcc ccaaccaaca aactcctccc tcaatgatgc caggggcagt     3300

gccaggcagc gggcacccag gcgtggcggg taatgctcct ttgggtttgc cttttggcat     3360

gccgcctcct cctcctcctc ctgctccatc catcatccca tttggtagtc tagctgactc     3420

catcagtatt aacctccccg ctcctcctaa cctgcatggg catcaccacc atctcccgtt     3480

cgccccgggc actctccccc cacctaacct gcctgtgtcc atggcgaacc ctctacatcc     3540

taacctgccg gcgaccacca ccatgccatc ttccttgcct ctcgggccgg ggctcggatc     3600

cgccgcagcc caaagccctg ccattgtggc agctgttcag ggcaacctcc tgcccagtgc     3660

cagcccactg ccagacccag gcacccccct gcctccagac cccacagccc cgagcccagg     3720

cacggtcacc cctgtgccac ctccacagtg aggagccagc cagacatctc tccccctcac     3780

cccctgtgga catcacggtt ccaggaacag cccttccccc accactggga ccctccccag     3840

cctggagagt tcatcactac gtaaggaaag ctccttccgc ccctccaaag ccctcaccat     3900

gcctaacaga ggcatgcatt tttatatcag attattcaag gacttctgtt taaaagatgt     3960

ttataatgtc tgggagagag gataggatgg gaatgctgcc ctaaaggaag ggctggtgaa     4020

aggtgtttat acaaggttct attaaccact tctaagggta cacctccctc caaactactg     4080

cattttctat ggattaaaaa aaaaaaaaaa aagtagattt taaaaagcca cattggagct     4140

cccttctacc cactaaaaaa taaccaattt ttacattttt tgagggggag tgagttttag     4200

gaaaggggaa ttaagattcc agggagagct ctggggatag aacagggcgc agattccatc     4260

tctccccaag ccccttttta gtgactaagt caaggcccca actcccctcc cccaccctac     4320

gctgagctta ttcgagttca ttcgtactaa taatccctcc tgcggcttcc tcattgttgc     4380

tgttttaggc caccccagct cagccaatga ttcctttccc tctgaatgtc agttttgttt     4440

ttaaaagtca cttgcttagt tgatgtcagc gtatgtgtat ttggtgggga aaacctaatt     4500

tcggggattt ctgtggtagg taataggaga agaaagggca ctgggggctg ttctccttcc     4560

ttccctgggc tgtatccatg gactcctgga aggcacagag aagggagcta taagaggatg     4620

tgaagtttta aaacctgaaa ttgtttttta aagcacttaa gcacctccat attatgactt     4680

ggtgggtcac cccttagctt cctccctctc ccaccaagac tatgagaact tcagctgata     4740

gctgggggct ccccagatga ggatgcaggg atttgggagc agtggaagag ggtgcccaac     4800

cttgggttgg accaaccctt ggctcgcagc tcaactctgc ttcccgcatt cctgctccac     4860

gtgtcccagc ttctcccctg tgacgggaag gcaggtgtga ctccaggctc tgcactggtt     4920

cttcttggtt cctcccacca ggccctttgt tcctcatgtc cccatgtttc tctccctctg     4980

cgtcttagca cctttcttct gttcaaagtt ttctgtaaat tttctctttt tttctttctt     5040

tctttttttt ttttttataa attaatttgc tttcagttcc atcttgtggg tgcattctgt     5100

gttcttacct gtggctgtca ggcaggggga ttgtgatggg agcagctttc ctggagtcct     5160

tcacagcggc gtttacctgg gccgaaagac actctgcaag ccacacggcc tacagacact     5220

gcgcctcccc acaaaacacg aacggcagca caactgtcga gactatgtgc tggtatagga     5280

gcagaggctc tcacctgccc taaaagctgt ttaagacttg gaaggacatt cccacaacat     5340

ggaattttgt atctctgtcc cttcagaagt agtggtttca ctccttccct tattagagag     5400

gaggcaagcc ccttacctac ttttgttata attggccctt caccctgctg aggtgacgga     5460

caggcttagg cagtgctaat aatggcctgg ctttagctcc aataaacact ccacaggctt     5520

ccccacaaaa ggccttattg ggagcttggg agggcggggg ccagatttaa ggagctggaa     5580

gggtagga                                                              5588


<210>  324
<211>  5336
<212>  DNA
<213>  homo sapiens

<400>  324
gcggccgcgg cggcgggagg cggcgggagg cgggcggagg aggaggcgga ggaggcggga       60

gctgagctga gtggggcggg cggcggcggg gcccgagccg gagaagatgg cggtgcggaa      120

gaaggacggc ggccccaacg tgaagtacta cgaggccgcg gacaccgtga cccagttcga      180

caacgtgcgg ctgtggctcg gcaagaacta caagaagtat atacaagctg aaccacccac      240

caacaagtcc ctgtctagcc tggttgtaca gttgctacaa tttcaggaag aagtttttgg      300

caaacatgtc agcaatgcac cgctcactaa actgccgatc aaatgtttcc tagatttcaa      360

agcgggaggc tccttgtgcc acattcttgc agctgcctac aaattcaaga gtgaccaggg      420

atggcggcgt tacgatttcc agaatccatc acgcatggac cgcaatgtgg aaatgtttat      480

gaccattgag aagtccttgg tgcagaataa ttgcctgtct cgacctaaca tttttctgtg      540

cccagaaatt gagcccaaac tactagggaa attaaaggac attatcaaga gacaccaggg      600

aacagtcact gaggataaga acaatgcctc ccatgttgtg tatcctgtcc cggggaatct      660

agaagaagag gaatgggtac gaccagtcat gaagagggat aagcaggttc ttctgcactg      720

gggctactat cctgacagtt acgacacgtg gatcccagcg agtgaaattg aggcatctgt      780

ggaagatgct ccaactcctg agaaacctag gaaggttcat gcaaagtgga tcctggacac      840

cgacaccttc aatgaatgga tgaatgagga agactatgaa gtaaatgatg acaaaaaccc      900

tgtctcccgc cgaaagaaga tttcagccaa gacactgaca gatgaggtga acagcccaga      960

ttcagatcga cgggacaaga aggggggaaa ctataagaag aggaagcgct ccccctctcc     1020

ttcaccaacc ccagaagcaa agaagaaaaa tgctaagaaa ggtccctcaa caccttacac     1080

taagtcaaag cgtggccaca gagaagagga gcaagaagac ctgacaaagg acatggacga     1140

gccctcacca gtccccaatg tagaagaggt gacacttccc aaaacagtca acacaaagaa     1200

agactcagag tcggccccag tcaaaggcgg caccatgacc gacctggatg aacaggaaga     1260

tgaaagcatg gagacgacgg gcaaggatga ggatgagaac agtacgggga acaagggaga     1320

gcagaccaag aatccagacc tgcatgagga caatgtgact gaacagaccc accacatcat     1380

cattcccagc tacgctgcct ggtttgacta caatagtgtt catgccattg agcggagggc     1440

tctccccgag ttcttcaacg gcaagaacaa gtccaagact ccagagatct acctggccta     1500

tcgaaacttt atgattgaca cttaccgact gaacccccaa gagtatctta cctctaccgc     1560

ctgccgccga aacctagcgg gtgatgtctg tgccatcatg agggtccatg ccttcctaga     1620

acagtggggt cttattaact accaggtgga tgctgagagt cgaccaaccc caatggggcc     1680

tccgcctacc tctcacttcc atgtcttggc tgacacacca tcagggctgg tgcctctgca     1740

gcccaagaca cctcagggcc gccaggttga tgctgatacc aaggctgggc gaaagggcaa     1800

agagctggat gacctggtgc cagagacggc taagggcaag ccagagctgc agacctctgc     1860

ttcccaacaa atgctcaact ttcctgacaa aggcaaagag aaaccaacag acatgcaaaa     1920

ctttgggctg cgcacagaca tgtacacaaa aaagaatgtt ccctccaaga gcaaggctgc     1980

agccagtgcc actcgtgagt ggacagaaca ggaaaccctg cttctcctgg aggcactgga     2040

aatgtacaaa gatgactgga acaaagtgtc cgagcatgtg ggaagccgca cacaggacga     2100

gtgcatcttg cattttcttc gtcttcccat tgaagaccca tacctggagg actcagaggc     2160

ctccctaggc cccctggcct accaacccat ccccttcagt cagtcgggca accctgttat     2220

gagcactgtt gccttcctgg cctctgtcgt cgatccccga gtcgcctctg ctgctgcaaa     2280

gtcagcccta gaggagttct ccaaaatgaa ggaagaggta cccacggcct tggtggaggc     2340

ccatgttcga aaagtggaag aagcagccaa agtaacaggc aaggcggacc ctgccttcgg     2400

tctggaaagc agtggcattg caggaaccac ctctgatgag cctgagcgga ttgaggagag     2460

cgggaatgac gaggctcggg tggaaggcca ggccacagat gagaagaagg agcccaagga     2520

accccgagaa ggagggggtg ctatagagga ggaagcaaaa gagaaaacca gcgaggctcc     2580

caagaaggat gaggagaaag ggaaagaagg cgacagtgag aaggagtccg agaagagtga     2640

tggagaccca atagtcgatc ctgagaagga gaaggagcca aaggaagggc aggaggaagt     2700

gctgaaggaa gtggtggagt ctgaggggga aaggaagaca aaggtggagc gggacattgg     2760

cgagggcaac ctctccaccg ctgctgccgc cgccctggcc gccgccgcag tgaaagctaa     2820

gcacttggct gctgttgagg aaaggaagat caaatctttg gtggccctgc tggtggagac     2880

ccagatgaaa aagttggaga tcaaacttcg gcactttgag gagctggaga ctatcatgga     2940

ccgggagcga gaagcactgg agtatcagag gcagcagctc ctggccgaca gacaagcctt     3000

ccacatggag cagctgaagt atgcggagat gagggctcgg cagcagcact tccaacagat     3060

gcaccaacag cagcagcagc caccaccagc cctgccccca ggctcccagc ctatcccccc     3120

aacaggggct gctgggccac ccgcagtcca tggcttggct gtggctccag cctctgtagt     3180

ccctgctcct gctggcagtg gggcccctcc aggaagtttg ggcccttctg aacagattgg     3240

gcaggcaggg tcaactgcag ggccacagca gcagcaacca gctggagccc cccagcctgg     3300

ggcagtccca ccaggggttc ccccccctgg accccatggc ccctcaccgt tccccaacca     3360

acaaactcct ccctcaatga tgccaggggc agtgccaggc agcgggcacc caggcgtggc     3420

ggacccaggc acccccctgc ctccagaccc cacagccccg agcccaggca cggtcacccc     3480

tgtgccacct ccacagtgag gagccagcca gacatctctc cccctcaccc cctgtggaca     3540

tcacggttcc aggaacagcc cttcccccac cactgggacc ctccccagcc tggagagttc     3600

atcactacgt aaggaaagct ccttccgccc ctccaaagcc ctcaccatgc ctaacagagg     3660

catgcatttt tatatcagat tattcaagga cttctgttta aaagatgttt ataatgtctg     3720

ggagagagga taggatggga atgctgccct aaaggaaggg ctggtgaaag gtgtttatac     3780

aaggttctat taaccacttc taagggtaca cctccctcca aactactgca ttttctatgg     3840

attaaaaaaa aaaaaaaaaa gtagatttta aaaagccaca ttggagctcc cttctaccca     3900

ctaaaaaata accaattttt acattttttg agggggagtg agttttagga aaggggaatt     3960

aagattccag ggagagctct ggggatagaa cagggcgcag attccatctc tccccaagcc     4020

cctttttagt gactaagtca aggccccaac tcccctcccc caccctacgc tgagcttatt     4080

cgagttcatt cgtactaata atccctcctg cggcttcctc attgttgctg ttttaggcca     4140

ccccagctca gccaatgatt cctttccctc tgaatgtcag ttttgttttt aaaagtcact     4200

tgcttagttg atgtcagcgt atgtgtattt ggtggggaaa acctaatttc ggggatttct     4260

gtggtaggta ataggagaag aaagggcact gggggctgtt ctccttcctt ccctgggctg     4320

tatccatgga ctcctggaag gcacagagaa gggagctata agaggatgtg aagttttaaa     4380

acctgaaatt gttttttaaa gcacttaagc acctccatat tatgacttgg tgggtcaccc     4440

cttagcttcc tccctctccc accaagacta tgagaacttc agctgatagc tgggggctcc     4500

ccagatgagg atgcagggat ttgggagcag tggaagaggg tgcccaacct tgggttggac     4560

caacccttgg ctcgcagctc aactctgctt cccgcattcc tgctccacgt gtcccagctt     4620

ctcccctgtg acgggaaggc aggtgtgact ccaggctctg cactggttct tcttggttcc     4680

tcccaccagg ccctttgttc ctcatgtccc catgtttctc tccctctgcg tcttagcacc     4740

tttcttctgt tcaaagtttt ctgtaaattt tctctttttt tctttctttc tttttttttt     4800

ttttataaat taatttgctt tcagttccat cttgtgggtg cattctgtgt tcttacctgt     4860

ggctgtcagg cagggggatt gtgatgggag cagctttcct ggagtccttc acagcggcgt     4920

ttacctgggc cgaaagacac tctgcaagcc acacggccta cagacactgc gcctccccac     4980

aaaacacgaa cggcagcaca actgtcgaga ctatgtgctg gtataggagc agaggctctc     5040

acctgcccta aaagctgttt aagacttgga aggacattcc cacaacatgg aattttgtat     5100

ctctgtccct tcagaagtag tggtttcact ccttccctta ttagagagga ggcaagcccc     5160

ttacctactt ttgttataat tggcccttca ccctgctgag gtgacggaca ggcttaggca     5220

gtgctaataa tggcctggct ttagctccaa taaacactcc acaggcttcc ccacaaaagg     5280

ccttattggg agcttgggag ggcgggggcc agatttaagg agctggaagg gtagga         5336


<210>  325
<211>  6574
<212>  DNA
<213>  homo sapiens

<400>  325
aagagcaaaa agcgaaggcg caatctggac actgggagat tcggagcgca gggagtttga       60

gagaaacttt tattttgaag agaccaaggt tgaggggggg cttatttcct gacagctatt      120

tacttagagc aaatgattag ttttagaagg atggactata acattgaatc aattacaaaa      180

cgcggttttt gagcccatta ctgttggagc tacagggaga gaaacagagg aggagactgc      240

aagagatcat tggaggccgt gggcacgctc tttactccat gtgtgggaca ttcattgcgg      300

aataacatcg gaggagaagt ttcccagagc tatggggact tcccatccgg cgttcctggt      360

cttaggctgt cttctcacag ggctgagcct aatcctctgc cagctttcat taccctctat      420

ccttccaaat gaaaatgaaa aggttgtgca gctgaattca tccttttctc tgagatgctt      480

tggggagagt gaagtgagct ggcagtaccc catgtctgaa gaagagagct ccgatgtgga      540

aatcagaaat gaagaaaaca acagcggcct ttttgtgacg gtcttggaag tgagcagtgc      600

ctcggcggcc cacacagggt tgtacacttg ctattacaac cacactcaga cagaagagaa      660

tgagcttgaa ggcaggcaca tttacatcta tgtgccagac ccagatgtag cctttgtacc      720

tctaggaatg acggattatt tagtcatcgt ggaggatgat gattctgcca ttataccttg      780

tcgcacaact gatcccgaga ctcctgtaac cttacacaac agtgaggggg tggtacctgc      840

ctcctacgac agcagacagg gctttaatgg gaccttcact gtagggccct atatctgtga      900

ggccaccgtc aaaggaaaga agttccagac catcccattt aatgtttatg ctttaaaagc      960

aacatcagag ctggatctag aaatggaagc tcttaaaacc gtgtataagt caggggaaac     1020

gattgtggtc acctgtgctg tttttaacaa tgaggtggtt gaccttcaat ggacttaccc     1080

tggagaagtg aaaggcaaag gcatcacaat gctggaagaa atcaaagtcc catccatcaa     1140

attggtgtac actttgacgg tccccgaggc cacggtgaaa gacagtggag attacgaatg     1200

tgctgcccgc caggctacca gggaggtcaa agaaatgaag aaagtcacta tttctgtcca     1260

tgagaaaggt ttcattgaaa tcaaacccac cttcagccag ttggaagctg tcaacctgca     1320

tgaagtcaaa cattttgttg tagaggtgcg ggcctaccca cctcccagga tatcctggct     1380

gaaaaacaat ctgactctga ttgaaaatct cactgagatc accactgatg tggaaaagat     1440

tcaggaaata aggtatcgaa gcaaattaaa gctgatccgt gctaaggaag aagacagtgg     1500

ccattatact attgtagctc aaaatgaaga tgctgtgaag agctatactt ttgaactgtt     1560

aactcaagtt ccttcatcca ttctggactt ggtcgatgat caccatggct caactggggg     1620

acagacggtg aggtgcacag ctgaaggcac gccgcttcct gatattgagt ggatgatatg     1680

caaagatatt aagaaatgta ataatgaaac ttcctggact attttggcca acaatgtctc     1740

aaacatcatc acggagatcc actcccgaga caggagtacc gtggagggcc gtgtgacttt     1800

cgccaaagtg gaggagacca tcgccgtgcg atgcctggct aagaatctcc ttggagctga     1860

gaaccgagag ctgaagctgg tggctcccac cctgcgttct gaactcacgg tggctgctgc     1920

agtcctggtg ctgttggtga ttgtgatcat ctcacttatt gtcctggttg tcatttggaa     1980

acagaaaccg aggtatgaaa ttcgctggag ggtcattgaa tcaatcagcc cagatggaca     2040

tgaatatatt tatgtggacc cgatgcagct gccttatgac tcaagatggg agtttccaag     2100

agatggacta gtgcttggtc gggtcttggg gtctggagcg tttgggaagg tggttgaagg     2160

aacagcctat ggattaagcc ggtcccaacc tgtcatgaaa gttgcagtga agatgctaaa     2220

acccacggcc agatccagtg aaaaacaagc tctcatgtct gaactgaaga taatgactca     2280

cctggggcca catttgaaca ttgtaaactt gctgggagcc tgcaccaagt caggccccat     2340

ttacatcatc acagagtatt gcttctatgg agatttggtc aactatttgc ataagaatag     2400

ggatagcttc ctgagccacc acccagagaa gccaaagaaa gagctggata tctttggatt     2460

gaaccctgct gatgaaagca cacggagcta tgttatttta tcttttgaaa acaatggtga     2520

ctacatggac atgaagcagg ctgatactac acagtatgtc cccatgctag aaaggaaaga     2580

ggtttctaaa tattccgaca tccagagatc actctatgat cgtccagcct catataagaa     2640

gaaatctatg ttagactcag aagtcaaaaa cctcctttca gatgataact cagaaggcct     2700

tactttattg gatttgttga gcttcaccta tcaagttgcc cgaggaatgg agtttttggc     2760

ttcaaaaaat tgtgtccacc gtgatctggc tgctcgcaac gtcctcctgg cacaaggaaa     2820

aattgtgaag atctgtgact ttggcctggc cagagacatc atgcatgatt cgaactatgt     2880

gtcgaaaggc agtacctttc tgcccgtgaa gtggatggct cctgagagca tctttgacaa     2940

cctctacacc acactgagtg atgtctggtc ttatggcatt ctgctctggg agatcttttc     3000

ccttggtggc accccttacc ccggcatgat ggtggattct actttctaca ataagatcaa     3060

gagtgggtac cggatggcca agcctgacca cgctaccagt gaagtctacg agatcatggt     3120

gaaatgctgg aacagtgagc cggagaagag accctccttt taccacctga gtgagattgt     3180

ggagaatctg ctgcctggac aatataaaaa gagttatgaa aaaattcacc tggacttcct     3240

gaagagtgac catcctgctg tggcacgcat gcgtgtggac tcagacaatg catacattgg     3300

tgtcacctac aaaaacgagg aagacaagct gaaggactgg gagggtggtc tggatgagca     3360

gagactgagc gctgacagtg gctacatcat tcctctgcct gacattgacc ctgtccctga     3420

ggaggaggac ctgggcaaga ggaacagaca cagctcgcag acctctgaag agagtgccat     3480

tgagacgggt tccagcagtt ccaccttcat caagagagag gacgagacca ttgaagacat     3540

cgacatgatg gatgacatcg gcatagactc ttcagacctg gtggaagaca gcttcctgta     3600

actggcggat tcgaggggtt ccttccactt ctggggccac ctctggatcc cgttcagaaa     3660

accactttat tgcaatgcag aggttgagag gaggacttgg ttgatgttta aagagaagtt     3720

cccagccaag ggcctcgggg agcgttctaa atatgaatga atgggatatt ttgaaatgaa     3780

ctttgtcagt gttgcctctt gcaatgcctc agtagcatct cagtggtgtg tgaagtttgg     3840

agatagatgg ataagggaat aataggccac agaaggtgaa ctttgtgctt caaggacatt     3900

ggtgagagtc caacagacac aatttatact gcgacagaac ttcagcattg taattatgta     3960

aataactcta accaaggctg tgtttagatt gtattaacta tcttctttgg acttctgaag     4020

agaccactca atccatccat gtacttccct cttgaaacct gatgtcagct gctgttgaac     4080

tttttaaaga agtgcatgaa aaaccatttt tgaaccttaa aaggtactgg tactatagca     4140

ttttgctatc ttttttagtg ttaaagagat aaagaataat aattaaccaa ccttgtttaa     4200

tagatttggg tcatttagaa gcctgacaac tcattttcat attgtaatct atgtttataa     4260

tactactact gttatcagta atgctaaatg tgtaataatg taacatgatt tccctccaga     4320

gaaagcacaa tttaaaacaa tccttactaa gtaggtgatg agtttgacag tttttgacat     4380

ttatattaaa taacatgttt ctctataaag tatggtaata gctttagtga attaaattta     4440

gttgagcata gagaacaaag taaaagtagt gttgtccagg aagtcagaat ttttaactgt     4500

actgaatagg ttccccaatc catcgtatta aaaaacaatt aactgccctc tgaaataatg     4560

ggattagaaa caaacaaaac tcttaagtcc taaaagttct caatgtagag gcataaacct     4620

gtgctgaaca taacttctca tgtatattac ccaatggaaa atataatgat cagcaaaaag     4680

actggatttg cagaagtttt tttttttttt ttcttcatgc ctgatgaaag ctttggcgac     4740

cccaatatat gtattttttg aatctatgaa cctgaaaagg gtcagaagga tgcccagaca     4800

tcagcctcct tctttcaccc cttaccccaa agagaaagag tttgaaactc gagaccataa     4860

agatattctt tagtggaggc tggatgtgca ttagcctgga tcctcagttc tcaaatgtgt     4920

gtggcagcca ggatgactag atcctgggtt tccatccttg agattctgaa gtatgaagtc     4980

tgagggaaac cagagtctgt atttttctaa actccctggc tgttctgatc ggccagtttt     5040

cggaaacact gacttaggtt tcaggaagtt gccatgggaa acaaataatt tgaactttgg     5100

aacagggttg gcattcaacc acgcaggaag cctactattt aaatccttgg cttcaggtta     5160

gtgacattta atgccatcta gctagcaatt gcgaccttaa tttaactttc cagtcttagc     5220

tgaggctgag aaagctaaag tttggttttg acaggttttc caaaagtaaa gatgctactt     5280

cccactgtat gggggagatt gaactttccc cgtctcccgt cttctgcctc ccactccata     5340

ccccgccaag gaaaggcatg tacaaaaatt atgcaattca gtgttccaag tctctgtgta     5400

accagctcag tgttttggtg gaaaaaacat tttaagtttt actgataatt tgaggttaga     5460

tgggaggatg aattgtcaca tctatccaca ctgtcaaaca ggttggtgtg ggttcattgg     5520

cattctttgc aatactgctt aattgctgat accatatgaa tgaaacatgg gctgtgatta     5580

ctgcaatcac tgtgctatcg gcagatgatg ctttggaaga tgcagaagca ataataaagt     5640

acttgactac ctactggtgt aatctcaatg caagccccaa ctttcttatc caactttttc     5700

atagtaagtg cgaagactga gccagattgg ccaattaaaa acgaaaacct gactaggttc     5760

tgtagagcca attagacttg aaatacgttt gtgtttctag aatcacagct caagcattct     5820

gtttatcgct cactctccct tgtacagcct tattttgttg gtgctttgca ttttgatatt     5880

gctgtgagcc ttgcatgaca tcatgaggcc ggatgaaact tctcagtcca gcagtttcca     5940

gtcctaacaa atgctcccac ctgaatttgt atatgactgc atttgtgtgt gtgtgtgtgt     6000

tttcagcaaa ttccagattt gtttcctttt ggcctcctgc aaagtctcca gaagaaaatt     6060

tgccaatctt tcctactttc tatttttatg atgacaatca aagccggcct gagaaacact     6120

atttgtgact ttttaaacga ttagtgatgt ccttaaaatg tggtctgcca atctgtacaa     6180

aatggtccta tttttgtgaa gagggacata agataaaatg atgttataca tcaatatgta     6240

tatatgtatt tctatataga cttggagaat actgccaaaa catttatgac aagctgtatc     6300

actgccttcg tttatatttt tttaactgtg ataatcccca caggcacatt aactgttgca     6360

cttttgaatg tccaaaattt atattttaga aataataaaa agaaagatac ttacatgttc     6420

ccaaaacaat ggtgtggtga atgtgtgaga aaaactaact tgatagggtc taccaataca     6480

aaatgtatta cgaatgcccc tgttcatgtt tttgttttaa aacgtgtaaa tgaagatctt     6540

tatatttcaa taaatgatat ataatttaaa gtta                                 6574


<210>  326
<211>  3263
<212>  DNA
<213>  homo sapiens

<400>  326
agtccgctac ggaggtgagt gcagggctcc gggcgctgtg tgccgtgccc tgtcccccag       60

gctctgggtc cggttgagac gcactcccac cctgggtgct gcagggtctc ccgtggccta      120

cgctgccagg aggcccaggc tgggagaggg agcagggcgg cggcccgggg tgctcttccg      180

cgctcctcga ctccagcttt ggtctttgtg gctcaatagc ttgcgcccat tggaagggga      240

aacgcacgtt gctgtcccag ccacgaggcc ctgagcattt agcacttggt cgacggggga      300

agatgtgtcg gtgcagctaa aagatggaat atttgcgggc gtgaagcggc ccgaggtgat      360

accacaagtc ttttgacatg ctgaggtctg gcaggaacat taacctatgt gcatcccgag      420

tatggaccgt gtgctcccag gctcctgaca tagggtcatg aattagggcc gagtgggagc      480

gcagagcccc tcccagtcac ccggcagcag aagcagcccg gcttttggag gacattgtct      540

cctggagcag tgtcagtccc aaaagctcca gcccttctct gagacgggga ccaggggatg      600

gcagccatgc acctgacagc ctggccccag ggacttcacg gatcccctga agctcatcca      660

tggacttcca tggactacag ggcctgagct atggaattgg ccctagggca gcaggaacct      720

attgtttcag aagtcggtga cctttgagga cgtggctgtg tacttcaccc aggcggaatg      780

ggatggcctg tcccctgcac agaggaccct gtacagggat gtgatgctgg agaattatgg      840

gaatgtggcc tccctgggat ttccacttct caaacctgct gtgatctcac aactggaggg      900

aggaagtgag ctggggggct catctccact ggctgcagga acaggcctcc agggcctcca      960

gactgatatt cagactgaca atgatttgac aaaggaaatg tatgaaggaa aagagaatgt     1020

atcatttgaa cttcaaagag acttttccca ggaaacagac ttttcagaag cctctcttct     1080

agagaaacaa caggaagtcc actcagcagg aaatataaag aaggagaaga gcaacaccat     1140

tgatggaaca gtgaaagatg agacaagccc cgtggaggag tgttttttta gtcaaagttc     1200

aaactcatat cagtgtcata ccatcactgg agagcagccc tctgggtgta caggattggg     1260

gaaatccatc agctttgata caaaactcgt gaagcatgaa ataattaatt ctgaggaaag     1320

acctttcaaa tgtgaagaat tagtagagcc ctttaggtgt gactctcaac ttattcaaca     1380

tcaagagaac aacactgagg aaaagcctta tcagtgttcg gagtgtggca aagctttcag     1440

cattaatgag aaattaattt ggcatcagag acttcacagt ggggagaaac ccttcaaatg     1500

tgtggagtgt gggaaaagct tcagctacag ttcccattat atcacacatc agacaatcca     1560

cagtggggag aagccctatc agtgtaagat gtgtgggaag gccttcagtg ttaatggaag     1620

cctaagtagg catcagagaa tccatacggg agagaagccc tatcagtgca aggaatgtgg     1680

aaatggcttc agctgtagtt ctgcatatat tacacatcag agagtccaca ctggagagaa     1740

accttacgag tgtaatgact gtgggaaagc gttcaatgtt aatgcaaaat taattcaaca     1800

tcagagaatc catactggag agaaacctta tgaatgtaat gaatgtggaa aaggcttcag     1860

gtgcagctcc cagcttaggc agcatcagag catccacaca ggagaaaagc cctatcagtg     1920

taaagagtgt ggaaaaggct tcaataataa tacaaaactc attcagcatc agagaatcca     1980

cacaggtgag aaaccctatg aatgcactga atgtggaaaa gccttcagtg tcaaagggaa     2040

gttaatccaa caccagagaa ttcacacagg cgagaaaccc tatgagtgta atgaatgcgg     2100

gaaagccttc agatgtaact cccaatttcg gcagcatctg agaattcaca ctggggagaa     2160

gccctatgag tgtaatgagt gtggaaaggc cttcagcgtt aatgggaaac taatgcggca     2220

tcagagaatt cacactgggg agaaaccttt tgaatgtaat gagtgtggga gatgctttac     2280

ttctaaaaga aacctacttg atcatcaccg aatccatact ggagaaaagc cctatcaatg     2340

taaggaatgt gggaaagcct tcagtatcaa tgccaaacta actaggcatc agaggataca     2400

tactggggag aaacctttca aatgtatgga atgtgagaaa gcattcagct gtagttctaa     2460

ctatattgtg caccagagaa tccatacagg agagaaaccc tttcagtgta aggagtgtgg     2520

aaaagccttc catgttaatg cccatttaat tcggcatcag agaagccaca ctggggagaa     2580

acccttcaga tgtgtggaat gtggcaaagg cttcagcttt agttctgact acattataca     2640

tcagacagtc cacacttgga agaaacccta tatgtgtagt gtgtgtggga aagcattcag     2700

gtttagcttc cagctcagtc agcatcagag tgtccatagt gaaggaaaat cctaataatg     2760

agaaagatat agaaaactct taaggttaat gccaaaatgg atcaagtatc atcagattca     2820

tccattgaaa aacctccaag agggcatgaa tatggcagag tcttcatatg gaaacagttt     2880

ttattctatt cagtttaaat caggaaagga tgaccagtta aagagaaaca tccaaaaata     2940

gctttgtttt gtaccaacag gaattagaaa atataatgaa aagatttcgt tcccagcagc     3000

atcaagaaaa gtagattttc tagaaataaa cagttatgga ggacttgtat ggagaaattt     3060

aagtcttcac tgagggccac tttacaaagg aaatttgaat aaatggagag agagagaagc     3120

cttgttgttg gataggaaaa cccgtactaa agatactcta cctacattaa tttatttgtt     3180

taatttttga caacaagcat gtattacttt tgaaaagatg aaaaataaag atttatttaa     3240

aaaaggaaaa aaaaaaaaaa aaa                                             3263


<210>  327
<211>  4291
<212>  DNA
<213>  homo sapiens

<400>  327
actcgtcact gcgcagccaa tcggcaggcg ggaagcactc cggcccgaac gtgcgggcgg       60

ggcagggtgg cggccccgca cggtagggga gcagagtggg caggccgggg gtgagggctc      120

gcgctccggg agctgcacgg ggctgcgtgg aaagagcgcc gagcggtggc gtcgttgtcg      180

ccccctcctc gtcgggaaga atcgtttggt ctcctgccgt gcccggaatc ccagtcagaa      240

gttccagcct gccactgttc tctgatgcca tgccagcacc aactcaactg ttttttcctc      300

tcatccgtaa ctgtgaactg agcaggatct atggcactgc atgttactgc caccacaaac      360

atctctgttg ttcctcatcg tacattcctc agagtcgact gagatacaca cctcatccag      420

catatgctac cttttgcagg ccaaaggaga actggtggca gtacacccaa ggaaggagat      480

atgcttccac accacagaaa ttttacctca cacctccaca agtcaatagc atccttaaag      540

ctaatgaata cagtttcaaa gtgccagaat ttgacggcaa aaatgtcagt tctatccttg      600

gatttgacag caatcagctg cctgcaaatg cacccattga ggaccggaga agtgcagcaa      660

cctgcttgca gaccagaggg atgcttttgg gggtttttga tggccatgca ggttgtgctt      720

gttcccaggc agtcagtgaa agactctttt attatattgc tgtctctttg ttaccccatg      780

agactttgct agagattgaa aatgcagtgg agagcggccg ggcactgcta cccattctcc      840

agtggcacaa gcaccccaat gattacttta gtaaggaggc atccaaattg tactttaaca      900

gcttgaggac ttactggcaa gagcttatag acctcaacac tggtgagtcg actgatattg      960

atgttaagga ggctctaatt aatgccttca agaggcttga taatgacatc tccttggagg     1020

cgcaagttgg tgatcctaat tcttttctca actacctggt gcttcgagtg gcattttctg     1080

gagccactgc ttgtgtggcc catgtggatg gtgttgacct tcatgtggcc aatactggcg     1140

atagcagagc catgctgggt gtgcaggaag aggacggctc atggtcagca gtcacgctgt     1200

ctaatgacca caatgctcaa aatgaaagag aactagaacg gctgaaattg gaacatccaa     1260

agagtgaggc caagagtgtc gtgaaacagg atcggctgct tggcttgctg atgccattta     1320

gggcatttgg agatgtaaag ttcaaatgga gcattgacct tcaaaagaga gtgatagaat     1380

ctggcccaga ccagttgaat gacaatgaat ataccaagtt tattcctcct aattatcaca     1440

cacctcctta tctcactgct gagccagagg taacttacca ccgattaagg ccacaggata     1500

agtttctggt gttggctact gatgggttgt gggagactat gcataggcag gatgtggtta     1560

ggattgtggg tgagtaccta actggcatgc atcaccaaca gccaatagct gttggtggct     1620

acaaggtgac tctgggacag atgcatggcc ttttaacaga aaggagaacc aaaatgtcct     1680

cggtatttga ggatcagaac gcagcaaccc atctcattcg ccacgctgtg ggcaacaacg     1740

agtttgggac tgttgatcat gagcgcctct ctaaaatgct tagtcttcct gaagagcttg     1800

ctcgaatgta cagagatgac attacaatca ttgtagttca gttcaattct catgttgtag     1860

gggcgtatca aaaccaagaa tagtgagtgg ctctttcact ggcaattctc aaatgatata     1920

catttaaagg gcagattttt taaaaagata ctactataat aaacatttcc agttggtcat     1980

tctaagcatt tacccttttg atactctagc tagtcaggta ctccaaattg actttgcagc     2040

agggtggcag ggtcaggaga gtctggtcct gcctagctca gatttcatgg cacctgcact     2100

tgaagcaagt cacttcttta tcacaggtgt cttgaaacat tagcttcttt taccaacctg     2160

agaaaattag gatgacctgg caaataagat cttgaatagg ccaaaagcaa gtatcttgct     2220

gtgtgtagtc tcttggttaa agtgaagaaa cagtactgtt cacacctttc ttcactgaga     2280

ttccagtgta catgagaaca tatatttatt gcatgatttt ctagatacac agtctatgca     2340

ttattcatat acatttattt tagcctaaag tggttttcaa atccagttct tcaagccata     2400

aatgaccaag atccaagcaa tctgaatttg tttttgtgat tatttgactg gaatgcttct     2460

taagtggaat aactatactc cgttatccac ccgatttcct aatgtaattg aaagattttc     2520

tattttgcca cacacttgga gacaataagg gtttttagtt ttatctactc ttctattgaa     2580

gttaaagaaa gaaaaaaaga tttttttatt tgtattaatg aaaagcttta gtttaaaata     2640

aggagatcca gaataaaaag aagagactga tctcttcaat tattgtcatc tgtagccacc     2700

agcacatcac tcttatgtaa tccccaaagg cttggcatgc cgtaagtgtg tggtgggtag     2760

actgctgccg gggaatcgta cttcttattt agtaatgata agacttttca ttatttttgg     2820

aattttaaag atgacataaa taagtttaaa tatcaatttg gggagtaagg tttaatattg     2880

ccatcgggta ttgagacagg aggaagtttc tgtttttctc catttagaca taggtcaatt     2940

aaaatatttg ggtttaaaat gactaaatgc tttaaacata ttgtagctta agatatatgt     3000

gttaagatat atacatgaga aactttaaaa ggtaactact gtgcatgcct gatgcttaat     3060

agaatactta gtggcatcaa atgtttgcag cagtctccat aattatattc agtcccttct     3120

aatactgtat caatgtaaat gaaataaata tattcaaatt ggctttttga tatgcatcaa     3180

gtggcatttt gttcctgtgt ttaatagtga tctgtataca gctgtgcaca tattgtcatc     3240

acttattcta gcatcactgt taaggctgtg attatgtttg atattcacct ggattttaat     3300

acaagccaat atcagcttcc cattgtgtaa taacttgggt gtttaggagt cttttcacat     3360

tttttgggga tatgaactag atgttcaaga actccttctg gactgtggat actgaatcag     3420

tgtactattg gctgcagaat ttgtttcaat tgaaaataga ctcaggaaga ttgctgctca     3480

gaatatcata taatgtttat tttttgaggt gtttttgttt ttatttgtgt gttttttttt     3540

ttttaagtca gcttggaact tttttcctgg gtagtatttg ggagagggaa aggctgtact     3600

atatatttat ttctaaatgt tttgactggg catttttctt ttaatgaaat atgtggactg     3660

ctctagcaaa ccctattttc agctactatt tgaatattct tgaacaccac cactgaagag     3720

tttcatatac accaaataat gtctcatctc tatagtacag ggaatataaa attggtttcc     3780

tgtggtcatg atcaagatag tagtattatt acacaagaaa cttggtctgc agtctggaag     3840

cttgtctgct ctatagaaat gaaaatgcag catgaagttg acattgtgga aatgaaagta     3900

attgggtatt agaaatctga aagtactgtc atctaaaagc aattgtgatt ttattgtaat     3960

tggttgtcac tgttgtacgg tgtctagaat taaagaatac atgtaaactt tcatggtatt     4020

tagcctttct taaatttttt taaaatttaa actttctaac ctatgtattc aacttctgta     4080

tttatattta atcagtggtt catgttatat aatacaccct taactagtta aatggaatgt     4140

tggtatggta cagagtacca tattgctaag aaaactgtct tataaaagat gtatatgtgt     4200

gaagacatga aagtttaatg tacagaatgg ttggagaaat gcctatggtg aattaaagct     4260

tcatatctgc tttctgaaaa aaaaaaaaaa a                                    4291


<210>  328
<211>  4291
<212>  DNA
<213>  homo sapiens

<400>  328
actcgtcact gcgcagccaa tcggcaggcg ggaagcactc cggcccgaac gtgcgggcgg       60

ggcagggtgg cggccccgca cggtagggga gcagagtggg caggccgggg gtgagggctc      120

gcgctccggg agctgcacgg ggctgcgtgg aaagagcgcc gagcggtggc gtcgttgtcg      180

ccccctcctc gtcgggaaga atcgtttggt ctcctgccgt gcccggaatc ccagtcagaa      240

gttccagcct gccactgttc tctgatgcca tgccagcacc aactcaactg ttttttcctc      300

tcatccgtaa ctgtgaactg agcaggatct atggcactgc atgttactgc caccacaaac      360

atctctgttg ttcctcatcg tacattcctc agagtcgact gagatacaca cctcatccag      420

catatgctac cttttgcagg ccaaaggaga actggtggca gtacacccaa ggaaggagat      480

atgcttccac accacagaaa ttttacctca cacctccaca agtcaatagc atccttaaag      540

ctaatgaata cagtttcaaa gtgccagaat ttgacggcaa aaatgtcagt tctatccttg      600

gatttgacag caatcagctg cctgcaaatg cacccattga ggaccggaga agtgcagcaa      660

cctgcttgca gaccagaggg atgcttttgg gggtttttga tggccatgca ggttgtgctt      720

gttcccaggc agtcagtgaa agactctttt attatattgc tgtctctttg ttaccccatg      780

agactttgct agagattgaa aatgcagtgg agagcggccg ggcactgcta cccattctcc      840

agtggcacaa gcaccccaat gattacttta gtaaggaggc atccaaattg tactttaaca      900

gcttgaggac ttactggcaa gagcttatag acctcaacac tggtgagtcg actgatattg      960

atgttaagga ggctctaatt aatgccttca agaggcttga taatgacatc tccttggagg     1020

cgcaagttgg tgatcctaat tcttttctca actacctggt gcttcgagtg gcattttctg     1080

gagccactgc ttgtgtggcc catgtggatg gtgttgacct tcatgtggcc aatactggcg     1140

atagcagagc catgctgggt gtgcaggaag aggacggctc atggtcagca gtcacgctgt     1200

ctaatgacca caatgctcaa aatgaaagag aactagaacg gctgaaattg gaacatccaa     1260

agagtgaggc caagagtgtc gtgaaacagg atcggctgct tggcttgctg atgccattta     1320

gggcatttgg agatgtaaag ttcaaatgga gcattgacct tcaaaagaga gtgatagaat     1380

ctggcccaga ccagttgaat gacaatgaat ataccaagtt tattcctcct aattatcaca     1440

cacctcctta tctcactgct gagccagagg taacttacca ccgattaagg ccacaggata     1500

agtttctggt gttggctact gatgggttgt gggagactat gcataggcag gatgtggtta     1560

ggattgtggg tgagtaccta actggcatgc atcaccaaca gccaatagct gttggtggct     1620

acaaggtgac tctgggacag atgcatggcc ttttaacaga aaggagaacc aaaatgtcct     1680

cggtatttga ggatcagaac gcagcaaccc atctcattcg ccacgctgtg ggcaacaacg     1740

agtttgggac tgttgatcat gagcgcctct ctaaaatgct tagtcttcct gaagagcttg     1800

ctcgaatgta cagagatgac attacaatca ttgtagttca gttcaattct catgttgtag     1860

gggcgtatca aaaccaagaa tagtgagtgg ctctttcact ggcaattctc aaatgatata     1920

catttaaagg gcagattttt taaaaagata ctactataat aaacatttcc agttggtcat     1980

tctaagcatt tacccttttg atactctagc tagtcaggta ctccaaattg actttgcagc     2040

agggtggcag ggtcaggaga gtctggtcct gcctagctca gatttcatgg cacctgcact     2100

tgaagcaagt cacttcttta tcacaggtgt cttgaaacat tagcttcttt taccaacctg     2160

agaaaattag gatgacctgg caaataagat cttgaatagg ccaaaagcaa gtatcttgct     2220

gtgtgtagtc tcttggttaa agtgaagaaa cagtactgtt cacacctttc ttcactgaga     2280

ttccagtgta catgagaaca tatatttatt gcatgatttt ctagatacac agtctatgca     2340

ttattcatat acatttattt tagcctaaag tggttttcaa atccagttct tcaagccata     2400

aatgaccaag atccaagcaa tctgaatttg tttttgtgat tatttgactg gaatgcttct     2460

taagtggaat aactatactc cgttatccac ccgatttcct aatgtaattg aaagattttc     2520

tattttgcca cacacttgga gacaataagg gtttttagtt ttatctactc ttctattgaa     2580

gttaaagaaa gaaaaaaaga tttttttatt tgtattaatg aaaagcttta gtttaaaata     2640

aggagatcca gaataaaaag aagagactga tctcttcaat tattgtcatc tgtagccacc     2700

agcacatcac tcttatgtaa tccccaaagg cttggcatgc cgtaagtgtg tggtgggtag     2760

actgctgccg gggaatcgta cttcttattt agtaatgata agacttttca ttatttttgg     2820

aattttaaag atgacataaa taagtttaaa tatcaatttg gggagtaagg tttaatattg     2880

ccatcgggta ttgagacagg aggaagtttc tgtttttctc catttagaca taggtcaatt     2940

aaaatatttg ggtttaaaat gactaaatgc tttaaacata ttgtagctta agatatatgt     3000

gttaagatat atacatgaga aactttaaaa ggtaactact gtgcatgcct gatgcttaat     3060

agaatactta gtggcatcaa atgtttgcag cagtctccat aattatattc agtcccttct     3120

aatactgtat caatgtaaat gaaataaata tattcaaatt ggctttttga tatgcatcaa     3180

gtggcatttt gttcctgtgt ttaatagtga tctgtataca gctgtgcaca tattgtcatc     3240

acttattcta gcatcactgt taaggctgtg attatgtttg atattcacct ggattttaat     3300

acaagccaat atcagcttcc cattgtgtaa taacttgggt gtttaggagt cttttcacat     3360

tttttgggga tatgaactag atgttcaaga actccttctg gactgtggat actgaatcag     3420

tgtactattg gctgcagaat ttgtttcaat tgaaaataga ctcaggaaga ttgctgctca     3480

gaatatcata taatgtttat tttttgaggt gtttttgttt ttatttgtgt gttttttttt     3540

ttttaagtca gcttggaact tttttcctgg gtagtatttg ggagagggaa aggctgtact     3600

atatatttat ttctaaatgt tttgactggg catttttctt ttaatgaaat atgtggactg     3660

ctctagcaaa ccctattttc agctactatt tgaatattct tgaacaccac cactgaagag     3720

tttcatatac accaaataat gtctcatctc tatagtacag ggaatataaa attggtttcc     3780

tgtggtcatg atcaagatag tagtattatt acacaagaaa cttggtctgc agtctggaag     3840

cttgtctgct ctatagaaat gaaaatgcag catgaagttg acattgtgga aatgaaagta     3900

attgggtatt agaaatctga aagtactgtc atctaaaagc aattgtgatt ttattgtaat     3960

tggttgtcac tgttgtacgg tgtctagaat taaagaatac atgtaaactt tcatggtatt     4020

tagcctttct taaatttttt taaaatttaa actttctaac ctatgtattc aacttctgta     4080

tttatattta atcagtggtt catgttatat aatacaccct taactagtta aatggaatgt     4140

tggtatggta cagagtacca tattgctaag aaaactgtct tataaaagat gtatatgtgt     4200

gaagacatga aagtttaatg tacagaatgg ttggagaaat gcctatggtg aattaaagct     4260

tcatatctgc tttctgaaaa aaaaaaaaaa a                                    4291


<210>  329
<211>  3922
<212>  DNA
<213>  homo sapiens

<400>  329
attctaacac acagacaggg agttagtgtg tgcggatctg tggtggagaa ggtatctcat       60

tcctctctaa catcatctcc actttgcatc tgtctctctt agtctgcttt ttttccaccg      120

atgtaacaga cctggagcca gcaggactca gaggaaagga cttaatcagg tttatgtgtc      180

ctaaaggtta tgaagacagt atggagtttc cagaccatag tagacatttg ctacagtgtc      240

tgagcgagca gagacaccag ggttttcttt gtgactgcac tgttctggtg ggagatgccc      300

agttccgagc gcaccgagct gtactggctt catgcagcat gtatttccac ctcttttaca      360

aggaccagct ggacaaaaga gacattgttc atctgaacag cgacattgtt acagcccccg      420

ctttcgctct cctgcttgaa ttcatgtatg aagggaaact ccagttcaaa gacttgccca      480

ttgaagacgt gctagcagct gccagttatc tccacatgta tgacattgtc aaagtctgca      540

aaaagaagct gaaagagaaa gccaccacgg aggcagacag caccaaaaag gaagaagatg      600

cttcaagttg ttcggacaaa gtcgagagtc tctccgatgg cagcagccac atagcaggcg      660

atttgcccag tgatgaagat gaaggagaag atgaaaaatt gaacatcctg cccagcaaaa      720

gggacttggc ggccgagcct gggaacatgt ggatgcgatt gccctcagac tcagcaggca      780

tcccccaggc tggcggagag gcagagccac acgccacagc agctggaaaa acagtagcca      840

gcccctgcag ctcaacagag tctttgtccc agaggtctgt cacctccgtg agggattcgg      900

cagatgttga ctgtgtgctg gacctgtctg tcaagtccag cctttcagga gttgaaaatc      960

tgaacagctc ttatttctct tcacaggacg tgctgagaag caacctggtg caggtgaagg     1020

tggagaaaga ggcttcctgt gatgagagtg atgttggcac taatgactat gacatggaac     1080

atagcactgt gaaagaaagt gtgagcacta ataacagggt acagtatgag ccggcccatc     1140

tggctcccct gagggaggac tcggtcttga gggagctgga ccgggaggac aaagccagtg     1200

atgatgagat gatgacccca gagagcgagc gtgtccaggt ggagggaggc atggagagca     1260

gtctgctccc ctacgtctcc aacatcctga gccccgcggg ccagatcttc atgtgccccc     1320

tgtgcaacaa ggtcttcccc agcccccaca tcctgcagat ccacctgagc acgcacttcc     1380

gcgagcagga cggcatccgc agcaagcccg ccgccgatgt caacgtgccc acgtgctcgc     1440

tgtgtgggaa gactttctct tgcatgtaca ccctcaagcg ccacgagagg actcactcgg     1500

gggagaagcc ctacacatgc acccagtgcg gcaagagctt ccagtactcg cacaacctga     1560

gccgccatgc cgtggtgcac acccgcgaga agccgcacgc ctgcaagtgg tgcgagcgca     1620

ggttcacgca gtccggggac ctgtacagac acattcgcaa gttccactgt gagttggtga     1680

actccttgtc ggtcaaaagc gaagcactga gcttgcctac tgtcagagac tggaccttag     1740

aagatagctc tcaagaactt tggaaataat tttatatata tataaataat atatatatat     1800

atacatatat ataaatagat ctctatatag ttgtggtacg gtctaaaagc agtcttgttt     1860

cctggaaata aaaagttggg atattaactt gtttttgcac tttagaatag catgagaatc     1920

tcactaattt agcattctga taaaagaaac tttagagcaa gtcagaatag agaggtgttt     1980

ttcctttgag gggatagggg aagtaagcca ataagaacct tttaaacaaa tcgtcctgtc     2040

acaaaatgct ttcatatggc ttaattttgt caacactgca ttgtcttttg agctcttttt     2100

tcccccccaa caaagttttt ttgttttttg tttttttttt taagtagaaa ttccctccag     2160

ttttattagc ctctttatat gtctcaaatt gcatgaattt tttctggctg ttggaaacct     2220

gaatgctttt agacccaaat ggaaaatttc tgaaatgctg gattatctat ttttaaacaa     2280

gcagttgact taaaactttc tgtggcaact tctggttttc tgacagttcc cagtgagaga     2340

aatgctgaaa gtacactggg atcactggga cactgtctta tgaaggtttg cttgggatga     2400

aaaaggatat tgcagcttca gcagtgttga actgtgtgtt taaaaatgtg aattactgtt     2460

attgtatact gtaattgatt acatgggctg ggggggtgtc aaagaacttg acaggttgtg     2520

ttgatgctct tagttgagtc ttgaaaagta aatattaacg ctacagaaat gcatgagttt     2580

caatatattt tttgtctttg tttgcattgt ataactttaa cgagtgagtt taaaattatt     2640

taatttcctt agaaaaatag caccatttgg aaaaaaaaac tggtgttatg aagaacgtaa     2700

atgcactgtt tttattttta ttttatataa tttaaattga ctttcccact gtctttaagt     2760

tgaaactgtt aagctgaata aaaacttaag ctgcaaattg ataacttcgc tacataacaa     2820

ggaaaatata aatgtttaca aacagcttaa agatttgcat gtgcagtgtg catttataac     2880

aaacttctaa ttgcacaaaa cccatgccag ctcagagttt aggtgtacac atttacccag     2940

ttgagcgttc ttagaataac tactgcacaa gttgacaata ggtcgttctc tctttttttt     3000

tgtttgctcc ctttttcttt ttctcccctt cctccttacc ctccctccct tactctcccc     3060

ccccaccacc accctccacc cccaactcat gaaaagattc tatggactga aaaagcccca     3120

ggctgaaagg actggactgc cttgattgac atggggaagg gggttagtag actatgtgga     3180

ttgcggcagc agaggctgca gcctaacgtg tggttttaat gaccagcacg caaggcaaaa     3240

gcattttgca cagtgtttgt tttcctgtct tgcacttaca aataaggtct atgggagtag     3300

catggaaaac gtttgctgtt tttccctttt ttttttaatt gcttttgttt aaaatttgat     3360

cgccttaact actgtaaaca tagcctattt ttgtgcttaa gatactgaat ggaaaactcc     3420

attgtgtgtt gctggactgt tttggaaata tttggttaaa tgtgtgttaa tttggctgta     3480

atggcattta aagcaaacaa acaaacaaaa aaagctgtga aaatggcctt ggagcattat     3540

ctttagttac ttgaagagtt tctagttttt ttaaaataca gtttatgtta aaataatttt     3600

tattaattta gagaagacaa tcaatgtctg tgagaaaacg gactttcttt tggattttct     3660

ttttgtggtc attgtgagtg attgcttttt ccttttctta gtttcacatt cttcctttgt     3720

tctaaaactt agactgacat ctagctttga caatcatagt atgttttatt ttcctgaggg     3780

ggaataactt ataatgctgt ttagttttgt actattggtg tgttggtgaa tttttaaact     3840

gtgtgctaac tgcaataaat tatatgaact gagaaaaaaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aa                                              3922


<210>  330
<211>  4319
<212>  DNA
<213>  homo sapiens

<400>  330
gttgtttgct aatttctgga ctaattatgc aatttcattt ttttttcttg attcagccaa       60

atgtgtgtgt gtgtgtttaa actgtgcttt ctaagcacag tcaggtagca aaagtaataa      120

aaaggatggt tgaacaagtt ttcttgtatg ttccaggata tgtttgggac ttttctttgt      180

ttattatatg agttgttccc tttgaaatta aagctatttt gtaggttttg tgggacataa      240

tttgataagt agagttaatt aaatttcttc tggaagagat ctaaattctt attcttagtg      300

agagactgta gttaaaggaa ggcttttaga acttgggttc aaggaagatg gagatgcgtc      360

ggaagctctt tggcgggggt gaggaagttc agaaagtgtg cattttcctt ctggcattta      420

ggtcttgtcc gtgtgatttg gtggtgcttg ggtcataagc ctgattaaaa ttcagggaca      480

tgtaccacgg cggccaaagc ggaattaatt tttttatatg gggactggag cgctgaaaag      540

ttgttcctga ccaggctcta atgagaaatt cctctctccc caggttatga agacagtatg      600

gagtttccag accatagtag acatttgcta cagtgtctga gcgagcagag acaccagggt      660

tttctttgtg actgcactgt tctggtggga gatgcccagt tccgagcgca ccgagctgta      720

ctggcttcat gcagcatgta tttccacctc ttttacaagg accagctgga caaaagagac      780

attgttcatc tgaacagcga cattgttaca gcccccgctt tcgctctcct gcttgaattc      840

atgtatgaag ggaaactcca gttcaaagac ttgcccattg aagacgtgct agcagctgcc      900

agttatctcc acatgtatga cattgtcaaa gtctgcaaaa agaagctgaa agagaaagcc      960

accacggagg cagacagcac caaaaaggaa gaagatgctt caagttgttc ggacaaagtc     1020

gagagtctct ccgatggcag cagccacata gcaggcgatt tgcccagtga tgaagatgaa     1080

ggagaagatg aaaaattgaa catcctgccc agcaaaaggg acttggcggc cgagcctggg     1140

aacatgtgga tgcgattgcc ctcagactca gcaggcatcc cccaggctgg cggagaggca     1200

gagccacacg ccacagcagc tggaaaaaca gtagccagcc cctgcagctc aacagagtct     1260

ttgtcccaga ggtctgtcac ctccgtgagg gattcggcag atgttgactg tgtgctggac     1320

ctgtctgtca agtccagcct ttcaggagtt gaaaatctga acagctctta tttctcttca     1380

caggacgtgc tgagaagcaa cctggtgcag gtgaaggtgg agaaagaggc ttcctgtgat     1440

gagagtgatg ttggcactaa tgactatgac atggaacata gcactgtgaa agaaagtgtg     1500

agcactaata acagggtaca gtatgagccg gcccatctgg ctcccctgag ggaggactcg     1560

gtcttgaggg agctggaccg ggaggacaaa gccagtgatg atgagatgat gaccccagag     1620

agcgagcgtg tccaggtgga gggaggcatg gagagcagtc tgctccccta cgtctccaac     1680

atcctgagcc ccgcgggcca gatcttcatg tgccccctgt gcaacaaggt cttccccagc     1740

ccccacatcc tgcagatcca cctgagcacg cacttccgcg agcaggacgg catccgcagc     1800

aagcccgccg ccgatgtcaa cgtgcccacg tgctcgctgt gtgggaagac tttctcttgc     1860

atgtacaccc tcaagcgcca cgagaggact cactcggggg agaagcccta cacatgcacc     1920

cagtgcggca agagcttcca gtactcgcac aacctgagcc gccatgccgt ggtgcacacc     1980

cgcgagaagc cgcacgcctg caagtggtgc gagcgcaggt tcacgcagtc cggggacctg     2040

tacagacaca ttcgcaagtt ccactgtgag ttggtgaact ccttgtcggt caaaagcgaa     2100

gcactgagct tgcctactgt cagagactgg accttagaag atagctctca agaactttgg     2160

aaataatttt atatatatat aaataatata tatatatata catatatata aatagatctc     2220

tatatagttg tggtacggtc taaaagcagt cttgtttcct ggaaataaaa agttgggata     2280

ttaacttgtt tttgcacttt agaatagcat gagaatctca ctaatttagc attctgataa     2340

aagaaacttt agagcaagtc agaatagaga ggtgtttttc ctttgagggg ataggggaag     2400

taagccaata agaacctttt aaacaaatcg tcctgtcaca aaatgctttc atatggctta     2460

attttgtcaa cactgcattg tcttttgagc tcttttttcc cccccaacaa agtttttttg     2520

ttttttgttt ttttttttaa gtagaaattc cctccagttt tattagcctc tttatatgtc     2580

tcaaattgca tgaatttttt ctggctgttg gaaacctgaa tgcttttaga cccaaatgga     2640

aaatttctga aatgctggat tatctatttt taaacaagca gttgacttaa aactttctgt     2700

ggcaacttct ggttttctga cagttcccag tgagagaaat gctgaaagta cactgggatc     2760

actgggacac tgtcttatga aggtttgctt gggatgaaaa aggatattgc agcttcagca     2820

gtgttgaact gtgtgtttaa aaatgtgaat tactgttatt gtatactgta attgattaca     2880

tgggctgggg gggtgtcaaa gaacttgaca ggttgtgttg atgctcttag ttgagtcttg     2940

aaaagtaaat attaacgcta cagaaatgca tgagtttcaa tatatttttt gtctttgttt     3000

gcattgtata actttaacga gtgagtttaa aattatttaa tttccttaga aaaatagcac     3060

catttggaaa aaaaaactgg tgttatgaag aacgtaaatg cactgttttt atttttattt     3120

tatataattt aaattgactt tcccactgtc tttaagttga aactgttaag ctgaataaaa     3180

acttaagctg caaattgata acttcgctac ataacaagga aaatataaat gtttacaaac     3240

agcttaaaga tttgcatgtg cagtgtgcat ttataacaaa cttctaattg cacaaaaccc     3300

atgccagctc agagtttagg tgtacacatt tacccagttg agcgttctta gaataactac     3360

tgcacaagtt gacaataggt cgttctctct ttttttttgt ttgctccctt tttctttttc     3420

tccccttcct ccttaccctc cctcccttac tctccccccc caccaccacc ctccaccccc     3480

aactcatgaa aagattctat ggactgaaaa agccccaggc tgaaaggact ggactgcctt     3540

gattgacatg gggaaggggg ttagtagact atgtggattg cggcagcaga ggctgcagcc     3600

taacgtgtgg ttttaatgac cagcacgcaa ggcaaaagca ttttgcacag tgtttgtttt     3660

cctgtcttgc acttacaaat aaggtctatg ggagtagcat ggaaaacgtt tgctgttttt     3720

cccttttttt tttaattgct tttgtttaaa atttgatcgc cttaactact gtaaacatag     3780

cctatttttg tgcttaagat actgaatgga aaactccatt gtgtgttgct ggactgtttt     3840

ggaaatattt ggttaaatgt gtgttaattt ggctgtaatg gcatttaaag caaacaaaca     3900

aacaaaaaaa gctgtgaaaa tggccttgga gcattatctt tagttacttg aagagtttct     3960

agttttttta aaatacagtt tatgttaaaa taatttttat taatttagag aagacaatca     4020

atgtctgtga gaaaacggac tttcttttgg attttctttt tgtggtcatt gtgagtgatt     4080

gctttttcct tttcttagtt tcacattctt cctttgttct aaaacttaga ctgacatcta     4140

gctttgacaa tcatagtatg ttttattttc ctgaggggga ataacttata atgctgttta     4200

gttttgtact attggtgtgt tggtgaattt ttaaactgtg tgctaactgc aataaattat     4260

atgaactgag aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa      4319


<210>  331
<211>  8031
<212>  DNA
<213>  homo sapiens

<400>  331
agggatccta cctcttttga ccggagatgt tgaaaagcac gaccaaagtt tttggcttgg       60

tctcttgctt tccacaacga gataaagtct gaagcctgta actctccctg tcccgcggga      120

gcgtgcaaag ggagggaaga taagcggcgt gggtgagggg tggcggcgca gaacccagga      180

agggagcaga ggcgagagcc agcctccggc aggagggcgt agaccccggt gccagccaga      240

acggctccag ccttcccgcg gccagagagc cagcggcggg aggggacggg cgggacctcc      300

gcggacagcc ccgggtgcgg accagcgggc agcggccggc gagaccctcc ctggatccgc      360

ccagagctta ccggaccctg cgcgcccccg tcccggctcc cggccggctc gggggagaag      420

gcgcccgagg ggaggcgccg gacagatcgc gtttcggagg cggcgcaggt gctgtaaact      480

gcaaaccata atcctgtctt aatactgcaa acaaatcata gtggaactaa ggggaactta      540

atttactgtt tccaggttaa ctaaggtctc agctgtaaac caaaagtgag aggagacatt      600

aagattttca ttcttaccgg gttgtcttct tcctgaagag caatggagcc gcttttactt      660

ggaagaggac taatcgtata tctaatgttc ctcctgttaa aattctcaaa agcaattgaa      720

ataccatctt cagttcaaca ggttccaaca atcataaaac agtcaaaagt ccaagttgcc      780

tttcccttcg atgagtattt tcaaattgaa tgtgaagcta aaggaaatcc agaaccaaca      840

ttttcgtgga ctaaggatgg caaccctttt tatttcactg accatcggat aattccatcg      900

aacaattcag gaacattcag gatcccaaac gaggggcaca tatctcactt tcaagggaaa      960

taccgctgct ttgcttcaaa taaactggga atcgctatgt cagaagaaat agaatttata     1020

gttccaagtg ttccaaaatt cccaaaagaa aaaattgacc ctcttgaagt ggaggaggga     1080

gatccaattg tcctcccatg caatcctccc aaaggcctcc cacctttaca catttattgg     1140

atgaatattg aattagaaca catcgaacaa gatgaaagag tatacatgag ccaaaaggga     1200

gatctatact tcgcaaacgt ggaagaaaag gacagtcgca atgactactg ttgctttgct     1260

gcatttccaa gattaaggac tattgtacag aaaatgccaa tgaaactaac agttaacagt     1320

ttaaagcatg ctaatgactc aagttcatcc acagaaattg gttccaaggc aaattccatc     1380

aagcaaagaa aacccaaact gctgttgcct cccactgaga gtggcagtga gtcttcaatt     1440

accatcctca aaggggaaat cttgctgctt gagtgttttg ctgaaggctt gccaactcca     1500

caggttgatt ggaacaaaat tggtggtgac ttaccaaagg ggagagaaac aaaagaaaat     1560

tatggcaaga ctttgaagat agagaatgtc tcctaccagg acaaaggaaa ttatcgctgc     1620

acagccagca atttcttggg aacagccact cacgattttc acgttatagt agaagagcct     1680

cctcgctgga caaagaagcc tcagagtgct gtgtatagca ccggaagcaa tggcatcttg     1740

ttatgtgagg ctgaaggaga acctcaaccc acaatcaagt ggagagtcaa tggctcccca     1800

gttgacaatc atccatttgc tggtgatgtt gtcttcccca gggaaatcag ttttaccaac     1860

cttcaaccaa atcatactgc tgtgtaccag tgtgaagcct caaatgtcca tggaactatc     1920

cttgccaatg ccaatattga tgttgtggat gtccgtccat tgatacaaac caaagatgga     1980

gaaaattacg ctacagtggt tgggtacagt gctttcttac attgcgagtt ctttgcttca     2040

cctgaggcag tcgtgtcctg gcagaaggtg gaagaagtga aacccctgga gggcaggcgg     2100

tatcatatct atgaaaatgg cacattgcag atcaacagaa ccaccgaaga agatgctggg     2160

tcttactcat gttgggtaga aaatgctata ggaaaaactg cagtcacagc caatttggat     2220

attagaaatg ctacaaaact tagagtttct cctaagaatc ctcgtatccc caaattgcat     2280

atgcttgaat tacattgtga aagcaaatgt gactcacatt tgaaacacag tttgaagttg     2340

tcctggagta aagatggaga agcctttgaa attaatggca cagaagatgg caggataatt     2400

attgatggag ctaatttgac catatctaat gtaactttag aggaccaagg tatttactgc     2460

tgttcagctc atactgctct agacagtgct gccgatataa ctcaagtaac tgttcttgat     2520

gttccggatc caccagaaaa ccttcacttg tctgaaagac agaacaggag tgttcggctg     2580

acctgggaag ctggagctga ccacaacagc aatattagcg agtatattgt tgaatttgaa     2640

ggaaacaaag aagagcctgg aaggtgggag gaactgacca gagtccaagg aaagaaaacc     2700

acagttatct tacctttggc tccatttgtg agataccagt tcagggtcat agccgtgaac     2760

gaagtaggga gaagtcagcc tagccagccg tcagaccatc atgaaacacc accagcagct     2820

ccagatagga atccacaaaa cataagggtt caagcctctc aacccaagga aatgattata     2880

aagtgggagc ctttgaaatc catggagcag aatggaccag gcctagagta cagagtgacc     2940

tggaagccac agggagcccc agtggagtgg gaagaagaaa cagtcacaaa ccacacattg     3000

cgggtgatga cgcctgctgt ctatgcccct tatgatgtca aggtccaggc tatcaatcaa     3060

ctaggatctg ggcctgaccc tcagtcagtg actctctatt ctggagaaga ctatcctgat     3120

acagctccag tgatccatgg ggtggacgtt ataaacagta cattagttaa agttacctgg     3180

tcaacagttc caaaggacag agtacatgga cgtctgaaag gctatcagat aaattggtgg     3240

aaaacaaaaa gtctgttgga tggaagaaca catcccaaag aagtgaacat tctaagattt     3300

tcaggacaaa gaaactctgg aatggttcct tccttagatg cctttagtga atttcattta     3360

acagtcttag cctataactc taaaggagct ggtcctgaaa gtgagcctta tatatttcaa     3420

acaccagaag gagtacctga acagccaact tttctaaagg tcatcaaagt tgataaagac     3480

actgccactt tatcttgggg actacctaag aaattaaatg gaaacttaac tggctatctt     3540

ttgcaatatc agataataaa tgacacctac gagattggag aattaaatga tattaacatt     3600

acaactccat caaagcccag ctggcacctc tcaaacctga atgcaactac caagtacaaa     3660

ttctacttga gggcttgcac ttcacagggc tgtggaaaac cgatcacgga ggaaagctcc     3720

accttaggag aagggagtaa aggtatcggg aagatatcag gagtaaatct tactcaaaag     3780

actcacccaa tagaggtatt tgagccggga gctgaacata tagttcgcct aatgactaag     3840

aattggggcg ataatgatag catttttcaa gatgtaattg agacaagagg gagagaatat     3900

gctggtttat atgatgacat ctccactcaa ggctggttta ttggactgat gtgtgcgatt     3960

gctcttctca cactactatt attaactgtt tgctttgtga agaggaatag aggtggaaag     4020

tactcagtta aagaaaagga agatttgcat ccagacccag aaattcagtc agtaaaagat     4080

gaaacctttg gtgaatacag tgacagtgat gaaaagcctc tcaaaggaag ccttcggtcc     4140

cttaataggg atatgcagcc tactgaaagt gctgacagct tagtcgaata cggagaggga     4200

gaccatggtc tcttcagtga agatggatca tttattggtg cctacgctgg atctaaggag     4260

aagggatctg ttgaaagcaa tggaagttct acagcaactt ttccccttcg ggcataaaca     4320

caacatatgt aagcaacgct actggttcac cccaaccttc catatttatc tgttcaaagg     4380

agcaagaact ttcatatagg aatagaaaca tgctggccga agatttcatc cagaagtcaa     4440

catcctgcaa ttatgttgaa aagagtagta ctttcttcaa aatataaaat gccaagcact     4500

tcaggcctat gttttgctta tattgttttc aggtgctcaa aatgcaaaac acaaaacaaa     4560

tcctgcattt agatacacct caactaaatc caaagtcccc attcagtata ttccatattt     4620

gcctgatttt actattcggt gtgtttgcat agatgttgct acttggtggg tttttctccg     4680

tatgcacatt ggtatacagt ctctgagaac tggcttggtg actttgcttc actacaggtt     4740

aaaagaccat aagcaaactg gttatttaaa atgtaaaaag gaatatgaaa gtcttattaa     4800

aacacttcat tgaaaatata cagtctaaat ttattattta aattttacta gcaaaagtct     4860

taggtgaaca atcaactagt atttgttgag ctcctatttg cccagagatg gtcatattta     4920

aacagaagta tacgtttttc agtttcaaca tgaatttttt tatttctgtc agttatgaca     4980

tccacaagca tcactttttg tgtctgtttt tttttttttt cttggactaa attcaactgc     5040

atggaagcgg tggtcagaag gttgttttat acgagaacag gcagaaagtg cccattgttc     5100

aggattctaa tagctacatc tacttaatat cttcatttct aaattgactg cttttacctt     5160

tttctcatgt ttatataatg gtatgcttgc atatatttca tgaatacatt gtacatatta     5220

tgttaatatt tacacaattt aaaatataga tgtgttttat tttgaagtga gaaaatgaac     5280

attaacaggc atgtttgtac agctagaata tattagtaag atactgtttt tcgtcattcc     5340

agagctacaa ctaataacac gaggttccaa agctgaagac tttgtataaa gtatttgggt     5400

tttgttcttg tattgctttc tttcaacagt ttcaaaataa aatatcatat aaatattgag     5460

ggaaatgttt tcatattttt caaaataggt ttttattgtt gaatgtacat ctaccccagc     5520

ccctcaaaag aaaaactgtt tacatagaaa ttcctacaca tacgtttgcg tatatgttat     5580

tttaaacatc tttgtggtga gaattttttc cccgatattc tccttctgtc aaagtcagaa     5640

caaattcagg gaatttattt tctggcagtt gtgctccagt ccttttaaaa ttgtacatga     5700

acatgtttta gaaacaatat ggaggatgat gcatacatgt cggtcaagtt cagcgctcga     5760

cattttatgg aaagattttt ttaaccttac cacgaaatac ttaactactg tttaagtgaa     5820

ttgacttatt tcactttagt ttttgaactg tgattattgg tatactgtta tatcctcaac     5880

ttggatttat ggtaacccct tatagttcat ggagaccaaa atttggggta tttataatag     5940

tcagcgcagg aatgcacatg gaatatctac ttgtcctttt gaacctcacg agtcatccag     6000

aatgtataga caggaaaagc atgtcttatt taaaactgta atttatgggc tcaggatctg     6060

accgcagtcc cgggagtaag catttcaaag ggggaaggca gtgtggtccc taccctgtgt     6120

gaatgtgagg atgtagacat ccatcagtgc aactcgagct ccatcctcct ccgatttcta     6180

aggttccagt tttctggagg gacagtcatc atgttttgat ttatctggga gaaaactgtg     6240

gtgcacagct tgtgaggagg gcaaggttgt gacgttcgag cttagttctg gtgttattct     6300

gtctcctctt ctttgtcatc agccaaaacg tggtttttaa agagagtcat gcaggttaga     6360

aataatgtca aaaatattta ggaatttaat aacctttaag tcagaaacta aaacaaatac     6420

tgaaatatta gctcttccta cacttcgtgt tcccctttag ctgcctgaaa atcaagattg     6480

ctcctgctca gatcttctga gtggctaaaa cttatggata tgaaaaatga gattgaatga     6540

tgactatgct ttgctatcat tgttaccttt cctcaatact atttggcaac tactgggact     6600

cttcagcaca aaaggaatag atctatgatt gaccctgatt ttaattgtga aattatatga     6660

ttcatatatt ttatgaatca gaataacctt caaataaaat aaatctaagt cggttaaaat     6720

ggatttcatg attttccctc agaaaatgag taacagagtc cacggcgtgc aatggtaatt     6780

ataaattggt gatgcttgtt tgcaaattgc ccactcgtga taagtcaaca gccaatattt     6840

aaaactttgt tcgttactgg ctttacccta actttctcta gtctactgtc aatatcattt     6900

taatgtaatt gattgtatat agtctcaaga atggttggtg ggcatgagtt cctagagaac     6960

tgtccaaggg ttgggaaaat ccaaattctc ttcctggttc cagcactgat tttgtacata     7020

aacattaggc aggttgctta acctttttat ttcaaactct ctcaactcta aagtgctaat     7080

aataatctca gttaccttat ctttgtcaca gggtgttctt ttttatgaag aaaaatttga     7140

aaatgataaa agctaagatg ccttctaact tcataagcaa acctttaact aattatgtat     7200

ctgaaagtca cccccacata ccaactcaac ttttttcctg tgaacacata aatatatttt     7260

tatagaaaaa caaatctaca taaaataaat ctactgttta gtgagcagta tgatttgtac     7320

atgccattga aaattattaa tcagaagaaa attaagcagg gtctttgcta tacaaaagtg     7380

ttttccacta attttgcatg cgtatttata agaaaaatgt gaatttggtg gttttattct     7440

atcggtataa aggcattgat attttagatg cacccgtgtt tgtaaaaatg tagagcacaa     7500

tggaattatg ctggaagtct caaataatat ttttttccta ttttatactc atggaagaga     7560

taagctaaag aggggacaat aatgagaaat gttggtgtgc ttttctaagc atttaaaaca     7620

taattgccaa ttgaaaccct aaatatgttt acataccatt aagatatgat tcatgtaaca     7680

atgttaaatt aattataatg ggattgggtt tgttatctgt ggtagtatat atcctagtgt     7740

tcctatagtg aaataagtag ggttcagcca aagctttctt tgttttgtac cttaaattgt     7800

tcgattacgt catcaaaaga gatgaaaggt atgtagaaca ggttcacgtg attacctttt     7860

tcttttggct tggattaata ttcatagtag aactttataa aacgtgtttg tattgtaggt     7920

ggtgtttgta ttatgcttat gactatgtat ggtttgaaaa tattttcatt atacatgaaa     7980

ttcaactttc caaataaaag ttctacttca tgtaatccaa aaaaaaaaaa a              8031


<210>  332
<211>  7233
<212>  DNA
<213>  homo sapiens

<400>  332
cgtgggctgc tgcggagccg gcagcgcagg cgggcggagc ggagctgccc ccgtggtggc       60

gggcgatgcc cccgtgagcc tccctcgccg cccctccccg ccccgcgtgc ctatccactc      120

ggagtccgcg ccagcctggg gccgggccgc gcctactgcc gggttcgcgg ggcggggtcc      180

cggggcagca cctgccccgc cttgcggagc cgcctcggcc tgtggaggcc ccctccctgt      240

ctggaccccg gccccacctc cggacccttt tatcacatcg cctcctctgg gagcctgccc      300

tgattgcctt cacctcattt cttgaaaatt ggtgttttgg cagaagtcaa ttgaagcctt      360

gtgcaaatgc cctaggggtg tgctgttggg aggcagcccc ctgtgatgcg gaacaccagg      420

ctcagattca tcagttcgag ctgcctgagg ccctgccacc ccggggacca tgtttaacgg      480

ggagccaggt cctgcctcat ctggggcctc caggaatgtg gtgcggagct ccagcattag      540

cggtgaaatc tgcggatccc agcaagccgg gggcggggct gggaccacca ccgccaagaa      600

gcggcggagc agcctgggtg ccaagatggt ggccatcgtg ggcctgactc agtggagcaa      660

gagcacactc cagcttccgc agcctgaagg ggccaccaag aagctgcgca gcaacatccg      720

ccggagcacg gagacaggca tcgcggtgga gatgcggagc cgggtcacac gccagggcag      780

ccgggagtcc accgatggga gcaccaacag caacagctcc gacggcacgt tcatcttccc      840

cactacccgg ctaggggctg aaagccagtt cagcgatttc ctggatgggc tgggaccagc      900

tcagattgtg gggcgacaga cactggcaac accacccatg ggagatgtgc acattgccat      960

catggaccgg agtggccagc tggaggtgga agtgattgaa gctcggggcc tgacccccaa     1020

accaggctcc aaatccctcc cagccaccta tatcaaggtt tacctgctgg agaatggggc     1080

ctgcttggcc aagaagaaga caaagatgac caagaagacc tgtgatcccc tgtaccagca     1140

ggctctgctc tttgacgagg gaccccaggg caaggtgctg caggtgatcg tctggggaga     1200

ctatggccgc atggaccaca agtgcttcat gggcatggcc cagatcatgc tggacgagct     1260

ggacctcagc gccgcggtca ccggctggta caaactcttc cccacctcct cagtggcaga     1320

ctccacactc ggatccctca ccaggcgcct gtcccagtct tccctggaga gtgccaccag     1380

cccctcatgc tcttaaggat gtcaggaaga ggccaggatg gtggtgtggg gaggggtgcc     1440

tgctggcccc atgtcctccc ctgtacatag tcttcgtgtc tttctggacc ccttgtcctg     1500

ctgcatgcct gttggctact gggctcatcc cagctggcag tggagactgt agtgtgtgcg     1560

tgtgtgcgtg cgtgtgtgtg tgtgtgtacg tgaccacgtt ctatctgttc atttgtctgg     1620

gtatagtcac tcctggtgat gatatgggct gaaatgtctc cacgtctctt tgtgtcttgt     1680

tgaaaagaaa cccaaaggag tgttgtgtgg acatgactca ccctgaggag tctccaggga     1740

tggaggtggg gcatgcggcc actggtcggt gctgcctggt cctggcctgg ggcagagcct     1800

gtgtgttctt cacctgtgcc tgctcctggt ggtctctgct ttgttttctg tcttgtcttt     1860

tgttccactc ttgactctcc cggctctgcc actgttttct gagaaatgta gcatccgctg     1920

cagctggcca cactgagggc cctctgggaa ccccacccca ctggagccgc tccggcagct     1980

cttcctgcca ctgaatgcgt tctgcagcat gtagcatgcc cacctagctc cctggccagg     2040

gccctgggga ggcagagggt acccagggga ctgagggctt agaaatgact ttctctatga     2100

ggctggaacc tcctccttct tccagtgaag cacgaggtct tggttccagg gttcctggcc     2160

aggtgccccc ttagcatttg ttcttcatct cctgtctctt caagcctccc cactccaccg     2220

tgccgaagga gctctgccag tgggcctggg caggcagcca cagagggcat gttatctgct     2280

aaagcaaaca gtcctcctga ggccctgagg gtggccctga ccccctcagg gctcattcct     2340

ggtgggcatg actcggtaag gaggttctgt gggtagggct gtttgctgga ataaggaggg     2400

ctgaggctga gttgttcccc gccactgttg aggatcccat ctgacatttg gggattcact     2460

gcatgaagtt gttcatttgg ggctccagtt tttgtgcatt tccagaccag ggtccctgtc     2520

tgggagctca gacttagctg ggctccagca gcctggctcc ggactctcgt ctgccaccat     2580

caccagctct gtctaagcaa tacttacccc tccgggcttc cctgctttcc tgtgccccac     2640

tgctgccctc tgcagagcca tctgctccag gcacccacct gcctctgctt gctttctcac     2700

ccatgtctgg ttggagcttc tcacagccac tcaaaccctg acttgatttg acaactgggc     2760

cctgttggtg gagaccagtg cctgaactgg accctgtgaa atctgtcccg tgggaatcct     2820

gaagtctgac tcaggaatgc ccagacctgt ccctgtccct cctcagctct agggtgaaag     2880

gcgagaggtt gcacaggaca tggacagagc agcccttggg tttgtatctg gtaggggaga     2940

aagcagcagg acagtggagg tgtgtggaag gcactctttc cacctctctc caggcattat     3000

ccccaggtgc tgaaatggct gtggccccag cacctgaggc aggggtacgc tacctggggt     3060

agcagtagaa aggtcttggg gtctgaatga cttggggcct ccattcataa ccaaagttgt     3120

aggggcatgg aggcagtggc gccttatgga taggtcatct cagcccaaag ggcctccttg     3180

gctggcatgg ttctgtgtta cgttgaagcc agagtcttat aacacctccc aagaaagata     3240

ggggaagaag ccagaacccc acctggcctg cccacaggac aagaagtggg taagggcagg     3300

aaggaaatga acggagttag ctcccaggct cctatctctg cctgagcctc tattcttata     3360

ttatcagaga aagggaccat tgggtgcata gagatgggga ggaggccact gggctgaatt     3420

ttctctttag gcggaaatgc tctccccagg cccattgcgt tcgtcaagtt cttggaaatg     3480

gacaaagggc tctgtcctcc tcgaccctag tgggggatca agaaggaaac tccgttgcaa     3540

aagggtattt taatctcctg tttatgatat attcacctct agagcagtca ctgtcagggt     3600

gttgcgaaaa tactctacac ctttgggatg atagggttgt tagtgaccca caggacagta     3660

tagatgtttg tggatgtagc actgagtggt gatacccaga ccagcagtca ccccaggaag     3720

tgggggctac ccataccctc attcctctgg tggggagctg cctgcagaga ggcctgccac     3780

tgggggttcc aggccgtggt gacccttgcc tctggggaag ggttagcaca ggggaggttc     3840

tagctggagg aggggtctga tgtgctggta acttgggctg acctacctac agtccctggc     3900

tgccaaaact gctcagcagt tgggccactc cactattcca cctctctaaa agaaggtaat     3960

ttcctcccca aattgacctt ggggaattat tcttttaacc ctttgcacca aataagttac     4020

tcatccccac ctggatttta ccccatgagg gtaaagttgt gtgaggctga cacgtctgtg     4080

tgatgcagtg tggctgcact taagggtctg tttctcagca tcatggatgc aggggcttgt     4140

ctgaaaagcc actctggacc tagcctgtcc cagaagagga gaatgcacaa gtgtaactcc     4200

tggttgtttg ctggggtggg ggagcatctg ctgtttgagg acggggggtg gggaaggaag     4260

gaacatgatc cctccagaag tctcccaccc tggggccaac tcactgccat gttcagtgtc     4320

ccggctccaa atgccccctt gcccagatga aaccctgcag tggttacagg aatggagctc     4380

tttgtcattc cacctcctct ggtcaggcga ggttcactgt gcatatggca gagacaggag     4440

tggccctgca gtgatgttgg gttgtgggca gggacagtga tggatgactc agagcgtctg     4500

tctttgtatt tctgctctgt tcattctgtc ccactttctt catagactcc ttttccctgc     4560

aatgggtttt tggtatgaaa aaggctccag taaatggagc caagtcttgg tttgacaagg     4620

ggaacttgat ccttcaggga agaatcatct ccaaaatgac tccccatctg gtttcttcta     4680

ccacccaatt ctactaggaa aggagcactt aggaggctct tgggatgcag caagtcccag     4740

gcaatgccag catttcatgg gggctgaggc agaacccagg agctccaaga aaggccaccc     4800

atagagctca tcctctgtgg aatcactgcc ggttagaaca ctgaggtcaa gccagtcctc     4860

ccatggtcat gccacccacc agggaagcat gcctgatctc ttctttactg ccagccttga     4920

ggagagcaga agcctccatt tttaaagaca ataaagacct ccaagggtac ttctttggaa     4980

atgaaatgta gcacaatctt agcctacgtt accaggagcc ctgacatgca accagggtcc     5040

ctcttccatg ccctgctgcc caggagttgc tgagctcctc ttcccctggg gttccagccc     5100

tcctaatacc tcatattccc catcttcctc agcccagaaa gcaatggggc tttagtgatg     5160

ctcctctttt gtgtctctct ggttgcctct agcactgtgc aaactctgca agaaattgct     5220

gcctttgctt gatgttgtag atgagttgcc ctccacctgg ctggagagat ggcacatcat     5280

tcagggccag aaggttgtcc agcagtgttt ctgcagtggc tgcagggaga tggaaaagaa     5340

gagccctgct tccctgcctc ctcctacctt tctcttccac tcctcagagt tttcttctcc     5400

agtatcctga catgtaaaga gattctttaa aatgctgctt cttctactgg actgtctttc     5460

actgagtagt cagggaggag atgaaaatgt ggacacatcc ccccgccttc tccctcaacc     5520

ttttcactca cgtcagaaga ggttggggca aaacaaaaca agcatgattg aagagcaggg     5580

gaagcccaca caatcaggtg agccctgatg ggggctggac tggcctggtc tggctgggaa     5640

aggattcttt taaaagcgtg cctgagcatc tcagagcaat gtcagtgatg ccaaagagag     5700

caacttggcc tccttgggca ccaactctga tggctgagtt gcacaaacgt ggctcagatg     5760

ttggcatgcc cgatggtggg accttgttct ctgataaagg gcttaatctt tccatgtagc     5820

aaagcaactt tccctccctc ccctcccccc gaaccctgag cttgggcttg tgtgggccca     5880

gcatggctgt gcctgtgagg gaagccacat cagtgagaga aagttgcatt ctctcagggg     5940

cctagattgg cttggggcag gtgcttgttg aaaagcatga gtgtttctgc tttgggaaac     6000

ccttccaggg ctctggttgg aaacttggcc agtaaggaca gggccttggg cctcccaagg     6060

agttcacaat gatgccagga agggtccctg agcctgggtt ccagtcagct tggctaacag     6120

aatggggctt gggaattcca ggggcaactg agcatccacc ccattagcca gtgatctgga     6180

cagggacagc tggctacagg gaatcaaagg ctgttctgta cagttttacc agaaactgtg     6240

accttgggta aggctcctca cttttctggg cctcaacttc ctcatctgca aaatcagagc     6300

attagctgct ctccccatga ttccctccca gttttaatta aaagtctctg atctggagca     6360

catgagggtt gcgagcctgg tgcacctggt tcctgtctcc gtgggctggt ttccttcagc     6420

ccctgatgcc caggctgggt gcaggctctc atctggtcca tgcccagatg ctgcctcaga     6480

caagaactct gggaatccta acagactctg ctttcctctc ttcgtggttt gtcctccctc     6540

ttttattctt gtgtaatgat gagacataat taagggtcat ctacaatgga caattttcaa     6600

ggtgctgatg tgatgtcaca acctccgcta catcctgagt aagtcagtgt ccccaacagc     6660

agatgaggct gggtctttcc tcatttctgc ttctgggatg acatcagtgg gagagttgaa     6720

gatctgagaa ttctaaagga aatgttctct gatgggagga gagagggaac ttatttccct     6780

tcaaagtagt ttgcttctta agaccactcc tccctccaga atgtctttaa ccagacatca     6840

tttcagaagg tggggcagct gcttccttag gaagagtggg cctgatagct caaccaactc     6900

ctttagcatg taaactcaca gaaggcaaga accccttttt ttagactttc caaatgcatc     6960

ctgcaaagag agagatagct gatagggact gacaagcaca ctgtttagat aagaagcaat     7020

tagcctttta tatctgtgct ctatacattt tctatgtgca gcatctttcc taacttgttg     7080

tggttcccgg gtggcaggtg cacagctggg agggactgcc ggctgtttcg tacaacattc     7140

ttgccaattc ccttgaggag aaaattcttc acatggcttc tgcatgtaca gtatttgggc     7200

agcaaaacat gattaaagtc agtttgaaaa tgg                                  7233


<210>  333
<211>  2450
<212>  DNA
<213>  homo sapiens

<400>  333
ggggcggggc tggcggcgcc ggcgcagccc gggggcggcg ggaggaggag gtggcggcgg       60

tggcgctggg agctcctgtc accgctgggg ccgggccggg cgggagtgca ggggacgtga      120

gggcgcaagg gccgggacat ggggcccgcc agccccgctg ctcgcggtct aagtcgccgc      180

ccgggccagc cgccgctgcc gctgctgctg ccactattgc tgctgcttct gcgcgcgcag      240

cccgccatcg ggagcctggc cggtgggagc cccggcgcgg ccgaggcccc ggggtcggcc      300

caggtggctg gactatgcgg gcgcctaacc cttcaccggg acctgcgcac cggccgctgg      360

gaaccagacc cacagcgctc tcgacgctgt ctccgggacc cgcagcgcgt gctggagtac      420

tgcagacaga tgtacccgga gctgcagatt gcacgtgtgg agcaggctac gcaggccatc      480

cccatggagc gctggtgcgg gggttcccgg agcggcagct gcgcccaccc ccaccaccag      540

gttgtgccct tccgctgcct gcctggtgaa tttgtgagtg aggccctgct ggtgcctgaa      600

ggctgccggt tcttgcacca ggagcgcatg gaccaatgtg agagttcaac ccggaggcat      660

caggaggcac aggaggcctg cagctcccag ggcctcatcc tgcacggctc gggcatgctc      720

ttaccctgtg gctcggatcg gttccgtggt gtggagtatg tgtgctgtcc ccctccaggg      780

acccccgacc catctgggac agcagttggt gacccctcca cccggtcctg gcccccgggg      840

agcagagtag agggggctga ggacgaggaa gaggaggaat ccttcccaca gccagtagat      900

gattacttcg tggagcctcc gcaggctgaa gaggaagagg aaacggtccc acccccaagc      960

tcccatacac ttgcagtggt cggcaaagtc actcccaccc cgaggcccac agacggtgtg     1020

gatatttact ttggcatgcc tggggaaatc agtgagcacg aggggttcct gagggccaag     1080

atggacctgg aggagcgtag gatgcgccag attaatgagg tgatgcgtga atgggccatg     1140

gcagacaacc agtccaagaa cctgcctaaa gccgacagac aggccctgaa tgagcacttc     1200

cagtccattc tgcagactct ggaggagcag gtgtctggtg agcgacagcg cctggtggaa     1260

acccacgcca cccgcgtcat cgcccttatc aacgaccagc gccgggctgc cttggagggc     1320

ttcctggcag ccctgcaggc agatccgcct caggcggagc gtgtcctgtt ggccctgcgg     1380

cgctacctgc gtgcggagca gaaggaacag aggcacacgc tgcgccacta ccagcatgtg     1440

gccgccgtgg atcccgagaa ggcacagcag atgcgcttcc aggtgcatac ccaccttcaa     1500

gtgattgagg agagggtgaa tcagagcctg ggcctgcttg accagaaccc ccacctggct     1560

caggagctgc ggccccaaat ccaggaactc ctccactctg aacacctggg tcccagtgaa     1620

ttggaagccc ctgcccctgg gggcagcagc gaggacaagg gtgggctgca gcctccagat     1680

tccaaggatg cagacacccc catgaccctt ccaaaagggt ccacagaaca agatgctgca     1740

tcccctgaga aagagaagat gaacccgctg gaacagtatg agcgaaaggt gaatgcgtct     1800

gttccaaggg gtttcccttt ccactcatcg gagattcaga gggatgagct ggcaccagct     1860

gggacagggg tgtcccgtga ggctgtgtcg ggtctgctga tcatgggagc gggcggaggc     1920

tccctcatcg tcctctccat gctgctcctg cgcaggaaga agccctacgg ggctatcagc     1980

catggcgtgg tggaggtgga ccccatgctg accctggagg agcagcagct ccgcgaactg     2040

cagcggcacg gctatgagaa ccccacttac cgcttcctgg aggaacgacc ctgacccggc     2100

ccccttcacc ccttcagccg agcccagacc tcccctcttc ctggagcccc agaaccccaa     2160

ctcccagcct agggcagcag ggagtcttga agtgatcatt tcacaccctt ttgtgagacg     2220

gctggaaatt cttatttccc ctttccaatt ccaaaattcc atccctaaga attcccagat     2280

agtcccagca gcctccccac gtggcacctc ctcaccttaa tttatttttt aagtttattt     2340

atggctcttt aaggtgaccg ccaccttggt cctagtgtct attccctgga attcaccctc     2400

tcatgtttcc ctactaacat cccaataaag tcctcttccc taccaggcca                2450


<210>  334
<211>  2519
<212>  DNA
<213>  homo sapiens

<400>  334
aatcttggtc gctaggacac ggctaacttc cgctttcttc cccctctcct aggctcaaac       60

tagtcaaatc ttgttcactc gaccaatggc aaatcggaag tgggcgggac ttcacaagtc      120

cggaccaaag aaacgcgagc ttagccctgg gtagcgcggc caatggccgt ggagcagccc      180

ctgtaaactg gctcgggcgc ccccacgccc gcccttcctt cttctcccag cattgccccc      240

cccacgtttc agcacagcgc tggccgcagt ctgacaggaa agggacggag ccaagatggc      300

ggcggccgac ggcgacgact cgctgtaccc catcgcggtg ctcatagacg aactccgcaa      360

tgaggacgtt cagcttcgcc tcaacagcat caagaagctg tccaccatcg ccttggccct      420

tggggttgaa aggacccgaa gtgagcttct gcctttcctt acagatacca tctatgatga      480

agatgaggtc ctcctggccc tggcagaaca gctgggaacc ttcactaccc tggtgggagg      540

cccagagtac gtgcactgcc tgctgccacc gctggagtcg ctggccacag tggaggagac      600

agtggtgcgg gacaaggcag tggagtcctt acgggccatc tcacacgagc actcgccctc      660

tgacctggag gcgcactttg tgccgctagt gaagcggctg gcgggcggcg actggttcac      720

ctcccgcacc tcggcctgcg gcctcttctc cgtctgctac ccccgagtgt ccagtgctgt      780

gaaggcggaa cttcgacagt acttccggaa cctgtgctca gatgacaccc ccatggtgcg      840

gcgggccgca gcctccaagc tgggggagtt tgccaaggtg ctggagctgg acaacgtcaa      900

gagtgagatc atccccatgt tctccaacct ggcctctgac gagcaggact cggtgcggct      960

gctggcggtg gaggcgtgcg tgaacatcgc ccagcttctg ccccaggagg atctggaggc     1020

cctggtgatg cccactctgc gccaggccgc tgaagacaag tcctggcgcg tccgctacat     1080

ggtggctgac aagttcacag agctccagaa agcagtgggg cctgagatca ccaagacaga     1140

cctggtccct gccttccaga acctgatgaa agactgtgag gccgaggtga gggccgcagc     1200

ctcccacaag gtcaaagagt tctgtgaaaa cctctcagct gactgtcggg agaatgtgat     1260

catgtcccag atcttgccct gcatcaagga gctggtgtcc gatgccaacc aacatgtcaa     1320

gtctgccctg gcctcagtca tcatgggtct ctctcccatc ttgggcaaag acaacaccat     1380

cgagcacctc ttgcccctct tcctggctca gctgaaggat gagtgccctg aggtacggct     1440

gaacatcatc tctaacctgg actgtgtgaa cgaggtgatt ggcatccggc agctgtccca     1500

gtccctgctc cctgccattg tggagctggc tgaggacgcc aagtggcggg tgcggctggc     1560

catcattgag tacatgcccc tcctggctgg acagctggga gtggagttct ttgatgagaa     1620

acttaactcc ttgtgcatgg cctggcttgt ggatcatgta tatgccatcc gcgaggcagc     1680

caccagcaac ctgaagaagc tagtggaaaa gtttgggaag gagtgggccc atgccacaat     1740

catccccaag gtcttggcca tgtccggaga ccccaactac ctgcaccgca tgactacgct     1800

cttctgcatc aatgtgctgt ctgaggtctg tgggcaggac atcaccacca agcacatgct     1860

acccacggtt ctgcgcatgg ctggggaccc ggttgccaat gtccgcttca atgtggccaa     1920

gtctctgcag aagatagggc ccatcctgga caacagcacc ttgcagagtg aagtcaagcc     1980

catcctagag aagctgaccc aggaccagga tgtggacgtc aaatactttg cccaggaggc     2040

tctgactgtt ctgtctctcg cctgatgctg gaagaggagc aaacactggc ctctggtgtc     2100

caccctccaa cccccacaag tccctctttg gggagacact ggggggcctt tggctgtcac     2160

tccctgtgca tggtctgacc ccaggcccct tcccccagca cggttcctcc tctccccagc     2220

ctgggaagat gtctcactgt ccacctccca acgggctagg ggagcacggg gttggacagg     2280

acagtgacct tgggaggaag gggctactcc gcccacgtca gggagagatg tgagcatccc     2340

gggtcactgg atcctgctgc tgtaatggga acccctcccc catttacttc tccacctccc     2400

gtcctcccca tcattggttt ttttttgtgt gtcaactgtg ccgtttttat tttattcctt     2460

ttattttccc ccttttcaca gagaaataaa ggtctagaag tagttggtca aaaaaaaaa      2519


<210>  335
<211>  2775
<212>  DNA
<213>  homo sapiens

<400>  335
agagctgtgg acctgccagc ctgcgaggcg gaggacgggc tccatctctt agaaacgcct       60

acggcgcatg ctctatgggg tcaactgggg ggctggcaag cggcagcgct ggtctggggc      120

ggagtctccg aggcacttcc cggtggctgg ctgctctgat tggctgaaca aatagtccga      180

gggtggtggg catccgccct cccgacaagg cagaccaggc cccctgcagg tcccctatcc      240

gcaccccggc ccctgagagc tggcactgcg actcgagaca gcggcccggc aggacagctc      300

cagaatgaaa atgcggttct tggggttggt ggtctgtttg gttctctgga ccctgcattc      360

tgaggggtct ggagggaaac tgacagctgt ggatcctgaa acaaacatga atgtgagtga      420

aattatctct tactggggat tccctagtga ggaataccta gttgagacag aagatggata      480

tattctgtgc cttaaccgaa ttcctcatgg gaggaagaac cattctgaca aaggtcccaa      540

accagttgtc ttcctgcaac atggcttgct ggcagattct agtaactggg tcacaaacct      600

tgccaacagc agcctgggct tcattcttgc tgatgctggt tttgacgtgt ggatgggcaa      660

cagcagagga aatacctggt ctcggaaaca taagacactc tcagtttctc aggatgaatt      720

ctgggctttc agttatgatg agatggcaaa atatgaccta ccagcttcca ttaacttcat      780

tctgaataaa actggccaag aacaagtgta ttatgtgggt cattctcaag gcaccactat      840

aggttttata gcattttcac agatccctga gctggctaaa aggattaaaa tgttttttgc      900

cctgggtcct gtggcttccg tcgccttctg tactagccct atggccaaat taggacgatt      960

accagatcat ctcattaagg acttatttgg agacaaagaa tttcttcccc agagtgcgtt     1020

tttgaagtgg ctgggtaccc acgtttgcac tcatgtcata ctgaaggagc tctgtggaaa     1080

tctctgtttt cttctgtgtg gatttaatga gagaaattta aatatgtcta gagtggatgt     1140

atatacaaca cattctcctg ctggaacttc tgtgcaaaac atgttacact ggagccaggc     1200

tgttaaattc caaaagtttc aagcctttga ctggggaagc agtgccaaga attattttca     1260

ttacaaccag agttatcctc ccacatacaa tgtgaaggac atgcttgtgc cgactgcagt     1320

ctggagcggg ggtcacgact ggcttgcaga tgtctacgac gtcaatatct tactgactca     1380

gatcaccaac ttggtgttcc atgagagcat tccggaatgg gagcatcttg acttcatttg     1440

gggcctggat gccccttgga ggctttataa taaaattatt aatctaatga ggaaatatca     1500

gtgaaagctg gacttgagct gtgtaccacc aagtcaatga ttatgtcatg tgaaaatgtg     1560

tttgcttcat ttctgtaaaa cacttgtttt tctttcccag gtcttttgtt tttttatatc     1620

caagaaaatg ataactttga agatgcccag ttcactctag tttcaattag aaacatacta     1680

gctatttttt ctttaattag ggctggaata ggaagccagt gtctcaacca tagtattgtc     1740

tctttaagtc ttttaaatat cactgatgtg taaaaaggtc attatatcca ttctgttttt     1800

aaaatttaaa atatattgac tttttgccct tcataggaca aagtaatata tgtgttggaa     1860

ttttaaaatt gtgttgtcat tggtaaatct gtcactgact taagcgaggt ataaaagtac     1920

gcagttttca tgtccttgcc ttaaagagct ctctagtcta acggtcttgt agttagagat     1980

ctaaatgaca ttttatcatg ttttcctgca gcaggtgcat agtcaaatcc agaaatatca     2040

cagctgtgcc agtaataagg atgctaacaa ttaattttat caaacctaac tgtgacagct     2100

gtgatttgac acgttttaat tgctcaggtt aaatgaaata gttttccggc gtcttcaaaa     2160

acaaattgca ctgataaaac aaaaacaaaa gtatgtttta aatgctttga agactgatac     2220

actcaaccat ctatattcat gagctctcaa tttcatggca ggccatagtt ctacttatct     2280

gagaagcaaa tccctgtgga gactatacca ctattttttc tgagattaat gtactcttgg     2340

agcccgctac tgtcgttatt gatcacatct gtgtgaagcc aaagccccgt ggttgcccat     2400

gagaagtgtc cttgttcatt ttcacccaaa tgaagtgtga acgtgatgtt ttcggatgca     2460

aactcagctc agggattcat tttgtgtctt agttttatat gcatccttat ttttaataca     2520

cctgcttcac gtccctatgt tgggaagtcc atatttgtct gcttttcttg cagcatcatt     2580

tccttacaat actgtccggt ggacaaaatg acaattgata tgtttttctg atataattac     2640

tttagctgca ctaacagtac aatgcttgtt aatggttaat ataggcaggg cgaatactac     2700

tttgtaactt ttaaagtctt aaacttttca ataaaattga gtgagactta taggcccaaa     2760

gaaaaaaaaa aaaaa                                                      2775


<210>  336
<211>  2674
<212>  DNA
<213>  homo sapiens

<400>  336
ggcacttccc ggtggctggc tgctctgatt ggctgaacaa atagtccgag ggtggtgggc       60

atccgccctc ccgacaaggc agaccaggcc ccctgcaggt cccctatccg caccccggcc      120

cctgagagct ggcactgcga ctcgagacag cggcccggca ggacagctcc aggtgagagt      180

gccggcgccg cggcgctgcc agaatgaaaa tgcggttctt ggggttggtg gtctgtttgg      240

ttctctggac cctgcattct gaggggtctg gagggaaact gacagctgtg gatcctgaaa      300

caaacatgaa tgtgagtgaa attatctctt actggggatt ccctagtgag gaatacctag      360

ttgagacaga agatggatat attctgtgcc ttaaccgaat tcctcatggg aggaagaacc      420

attctgacaa aggtcccaaa ccagttgtct tcctgcaaca tggcttgctg gcagattcta      480

gtaactgggt cacaaacctt gccaacagca gcctgggctt cattcttgct gatgctggtt      540

ttgacgtgtg gatgggcaac agcagaggaa atacctggtc tcggaaacat aagacactct      600

cagtttctca ggatgaattc tgggctttca gttatgatga gatggcaaaa tatgacctac      660

cagcttccat taacttcatt ctgaataaaa ctggccaaga acaagtgtat tatgtgggtc      720

attctcaagg caccactata ggttttatag cattttcaca gatccctgag ctggctaaaa      780

ggattaaaat gttttttgcc ctgggtcctg tggcttccgt cgccttctgt actagcccta      840

tggccaaatt aggacgatta ccagatcatc tcattaagga cttatttgga gacaaagaat      900

ttcttcccca gagtgcgttt ttgaagtggc tgggtaccca cgtttgcact catgtcatac      960

tgaaggagct ctgtggaaat ctctgttttc ttctgtgtgg atttaatgag agaaatttaa     1020

atatgtctag agtggatgta tatacaacac attctcctgc tggaacttct gtgcaaaaca     1080

tgttacactg gagccaggct gttaaattcc aaaagtttca agcctttgac tggggaagca     1140

gtgccaagaa ttattttcat tacaaccaga gttatcctcc cacatacaat gtgaaggaca     1200

tgcttgtgcc gactgcagtc tggagcgggg gtcacgactg gcttgcagat gtctacgacg     1260

tcaatatctt actgactcag atcaccaact tggtgttcca tgagagcatt ccggaatggg     1320

agcatcttga cttcatttgg ggcctggatg ccccttggag gctttataat aaaattatta     1380

atctaatgag gaaatatcag tgaaagctgg acttgagctg tgtaccacca agtcaatgat     1440

tatgtcatgt gaaaatgtgt ttgcttcatt tctgtaaaac acttgttttt ctttcccagg     1500

tcttttgttt ttttatatcc aagaaaatga taactttgaa gatgcccagt tcactctagt     1560

ttcaattaga aacatactag ctattttttc tttaattagg gctggaatag gaagccagtg     1620

tctcaaccat agtattgtct ctttaagtct tttaaatatc actgatgtgt aaaaaggtca     1680

ttatatccat tctgttttta aaatttaaaa tatattgact ttttgccctt cataggacaa     1740

agtaatatat gtgttggaat tttaaaattg tgttgtcatt ggtaaatctg tcactgactt     1800

aagcgaggta taaaagtacg cagttttcat gtccttgcct taaagagctc tctagtctaa     1860

cggtcttgta gttagagatc taaatgacat tttatcatgt tttcctgcag caggtgcata     1920

gtcaaatcca gaaatatcac agctgtgcca gtaataagga tgctaacaat taattttatc     1980

aaacctaact gtgacagctg tgatttgaca cgttttaatt gctcaggtta aatgaaatag     2040

ttttccggcg tcttcaaaaa caaattgcac tgataaaaca aaaacaaaag tatgttttaa     2100

atgctttgaa gactgataca ctcaaccatc tatattcatg agctctcaat ttcatggcag     2160

gccatagttc tacttatctg agaagcaaat ccctgtggag actataccac tattttttct     2220

gagattaatg tactcttgga gcccgctact gtcgttattg atcacatctg tgtgaagcca     2280

aagccccgtg gttgcccatg agaagtgtcc ttgttcattt tcacccaaat gaagtgtgaa     2340

cgtgatgttt tcggatgcaa actcagctca gggattcatt ttgtgtctta gttttatatg     2400

catccttatt tttaatacac ctgcttcacg tccctatgtt gggaagtcca tatttgtctg     2460

cttttcttgc agcatcattt ccttacaata ctgtccggtg gacaaaatga caattgatat     2520

gtttttctga tataattact ttagctgcac taacagtaca atgcttgtta atggttaata     2580

taggcagggc gaatactact ttgtaacttt taaagtctta aacttttcaa taaaattgag     2640

tgagacttat aggcccaaag aaaaaaaaaa aaaa                                 2674


<210>  337
<211>  1166
<212>  DNA
<213>  homo sapiens

<400>  337
attcccaact gccagtgatc tctgaagccg actctgaggc tccctctttg ctctaacaga       60

cagcagcgac tttaggctgg ataatagtca aattcttacc tcgctctttc actgctagta      120

agatcagatt gcgtttcttt cagttactct tcaatcgcca gtttcttgat ctgcttctaa      180

aagaagaagt agagaagata aatcctgtct tcaatacctg gaaggaaaaa caaaataacc      240

tcaactccgt tttgaaaaaa acattccaag aactttcatc agagatttta cttagatgat      300

ttacacaatg aagaaagtac atgcactttg ggcttctgta tgcctgctgc ttaatcttgc      360

ccctgcccct cttaatgctg attctgagga agatgaagaa cacacaatta tcacagatac      420

ggagttgcca ccactgaaac ttatgcattc attttgtgca ttcaaggcgg atgatggccc      480

atgtaaagca atcatgaaaa gatttttctt caatattttc actcgacagt gcgaagaatt      540

tatatatggg ggatgtgaag gaaatcagaa tcgatttgaa agtctggaag agtgcaaaaa      600

aatgtgtaca agagataatg caaacaggat tataaagaca acattgcaac aagaaaagcc      660

agatttctgc tttttggaag aagatcctgg aatatgtcga ggttatatta ccaggtattt      720

ttataacaat cagacaaaac agtgtgaacg tttcaagtat ggtggatgcc tgggcaatat      780

gaacaatttt gagacactgg aagaatgcaa gaacatttgt gaagatggtc cgaatggttt      840

ccaggtggat aattatggaa cccagctcaa tgctgtgaat aactccctga ctccgcaatc      900

aaccaaggtt cccagccttt ttgttacaaa agaaggaaca aatgatggtt ggaagaatgc      960

ggctcatatt taccaagtct ttctgaacgc cttctgcatt catgcatcca tgttctttct     1020

aggattggat agcatttcat gcctatgtta atatttgtgc ttttggcatt tccttaatat     1080

ttatatgtat acgtgatgcc tttgatagca tactgctaat aaagttttaa tatttacatg     1140

catagtaaaa aaaaaaaaaa aaaaaa                                          1166


<210>  338
<211>  3927
<212>  DNA
<213>  homo sapiens

<400>  338
attcccaact gccagtgatc tctgaagccg actctgaggc tccctctttg ctctaacaga       60

cagcagcgac tttaggctgg ataatagtca aattcttacc tcgctctttc actgctagta      120

agatcagatt gcgtttcttt cagttactct tcaatcgcca gtttcttgat ctgcttctaa      180

aagaagaagt agagaagata aatcctgtct tcaatacctg gaaggaaaaa caaaataacc      240

tcaactccgt tttgaaaaaa acattccaag aactttcatc agagatttta cttagatgat      300

ttacacaatg aagaaagtac atgcactttg ggcttctgta tgcctgctgc ttaatcttgc      360

ccctgcccct cttaatgctg attctgagga agatgaagaa cacacaatta tcacagatac      420

ggagttgcca ccactgaaac ttatgcattc attttgtgca ttcaaggcgg atgatggccc      480

atgtaaagca atcatgaaaa gatttttctt caatattttc actcgacagt gcgaagaatt      540

tatatatggg ggatgtgaag gaaatcagaa tcgatttgaa agtctggaag agtgcaaaaa      600

aatgtgtaca agagataatg caaacaggat tataaagaca acattgcaac aagaaaagcc      660

agatttctgc tttttggaag aagatcctgg aatatgtcga ggttatatta ccaggtattt      720

ttataacaat cagacaaaac agtgtgaacg tttcaagtat ggtggatgcc tgggcaatat      780

gaacaatttt gagacactgg aagaatgcaa gaacatttgt gaagatggtc cgaatggttt      840

ccaggtggat aattatggaa cccagctcaa tgctgtgaat aactccctga ctccgcaatc      900

aaccaaggtt cccagccttt ttgaatttca cggtccctca tggtgtctca ctccagcaga      960

cagaggattg tgtcgtgcca atgagaacag attctactac aattcagtca ttgggaaatg     1020

ccgcccattt aagtacagtg gatgtggggg aaatgaaaac aattttactt ccaaacaaga     1080

atgtctgagg gcatgtaaaa aaggtttcat ccaaagaata tcaaaaggag gcctaattaa     1140

aaccaaaaga aaaagaaaga agcagagagt gaaaatagca tatgaagaaa tttttgttaa     1200

aaatatgtga atttgttata gcaatgtaac attaattcta ctaaatattt tatatgaaat     1260

gtttcactat gattttctat ttttcttcta aaatgctttt aattaatatg ttcattaaat     1320

tttctatgct tattgtactt gttatcaaca cgtttgtatc agagttgctt ttctaatctt     1380

gttaaattgc ttattctagg tctgtaattt attaactggc tactgggaaa ttacttattt     1440

tctggatcta tctgtatttt catttaacta caaattatca tactaccggc tacatcaaat     1500

cagtcctttg attccatttg gtgaccatct gtttgagaat atgatcatgt aaatgattat     1560

ctcctttata gcctgtaacc agattaagga atacagctct taaaaaatca agaacttcct     1620

gagtttcaca tataaaatgg tgacaaacac ctgcttctga taaagtttat ccaattttgt     1680

atttatagta ttctattgta ataatagaat tctattatgt gcttccctcc ttagacatag     1740

tttttctcct tttgtactaa ccagtacttc catctatatt gagctaaact gtctttgaac     1800

agtcaactct gcatcatgtg cctgcctgat ttggattggt ttcacttttt tttttgtttg     1860

accatagccc attctatcag tcaagatgac tgaataattg tgtgttaaat acaactcatg     1920

ataaggagaa cctttatgga aacaagaagt tttatggcaa tcgagaggga attatttata     1980

tgtacttctt aatactatgc ttcccaatat tttttcttac taaaaataac aaaaatattt     2040

aaaccttctg aaatctattc agttatcatt aggatttgca cacaatgcaa ctaataattc     2100

atgctttaaa aagtaggtta tttctgttga agagaaaatt atcagcaggg aagagtctac     2160

tagaaaattc atgtgctagt cattcttggg gatttaatat tttgctggag ttaattcact     2220

atatccagac ctgtatcttt catttattgc tgagccatgt gcagtctggc atctcaacaa     2280

cctcaacaac ctcaacaacc tccaagacat gtcagtttct gtagtgttca cctcaaatct     2340

gacactggaa ttggaactga tttagaaaca accatttcat tcatttggta tgactagctt     2400

catgactagc ttcatgaata gcttcatgaa tagcttcatg acttctcgct aacaatgata     2460

gtataattct gcctgttctt caggattgaa attttgaact caatttagat ttcctgtttt     2520

ccctcatata ccacatctaa acagtctcca aatctttatg cttttttttt tttttttcga     2580

aaaagttcac ccaatcccta ggctttttac ttttttcttt ttcttttctt ttttcttgtt     2640

tttttttttt tttcattttg ttttgttttg ttatgttttt ttagacaggg tcccactctg     2700

tcacccaggc tggagtgcag tggtgcaatc acaggacact gaaacctccc acctagctgg     2760

gactagaggt gcaggccacc acaccagcta atttatgtaa tttttgtaga gacgagtttc     2820

accacgttac ctaggcttgt cttgaacacc tgggctcaag caatcttcca gccccagcct     2880

cccaaagtgc tgggattaca ggtataaacc acaatgcccc cgtttttact ctttactgca     2940

tccttcccat cagtattaat tcctcagaaa tttagtacat tcctccacca tttcaaaatg     3000

ctcccagaac tcacactagt tggtacttaa ctacaacctt caacctcacc atttaatttt     3060

gatgtatgtt tttggattta ccaacagtac tttctttcat gactactttg atttagttaa     3120

gaatgctcac tgtacactga atgttaatta ctcagctaat tcacactgat ttcctgttta     3180

aaaatatgat cccctccagg ccattcatgt gaagtcaggg tacagctgat gccagctaca     3240

gaatcactat gtttcaatat ggaatatgaa aagtcctaac acataattgc aaatcatttt     3300

ctactatggt atacaaattt tatcattaca aaatagtatc agcttttttc acttaaggaa     3360

aataatacat cttcattcaa atattcagtg cataaataat tgccttaaat tgagtctttg     3420

ctgtggaatt tgagagtttt ggaaatcaaa ggcccttgtg aaacatttcc tgttgccatt     3480

tatttataga tagcaatagc ttcaaatgag tgggaaagtc tacttaggtg aagtggtaaa     3540

tagtcactaa gattgtataa atagcgcatt gatgagttgc ctaattgttt tctccaacaa     3600

taaccactgg tccattggtt cactacttac tcaagaaaga catatactga gatggcttga     3660

aatgtttaat gcatgtgaac gttattttta ccgtgttttg gaaaaagatc ttgatgttat     3720

tgtcttcctt tattttccac aattaagtgc atctaactgt gaattgtata tggaattaca     3780

ttattcagca tatacatata tttacctgct ttgttcattc tctgtattca aaattaacag     3840

atcatgctga aaaccactca aacgattata ttttttacat tataagaagt aaaatatatt     3900

attctgaata atgaaaaaaa aaaaaaa                                         3927


<210>  339
<211>  5632
<212>  DNA
<213>  homo sapiens

<400>  339
tacttacccc gccagccccg ggaggctcgc agagcgagcg gcgccggcgt catgtgactg       60

cccggagttg gtgccaggag ccagagggga gccaggagcg gagccgcgcg gagccggggc      120

ccgagccgga gcgcagcgag agcgcccgcc gcacgcgcgc ccgtccccgt cccctgcggc      180

cgccaacgcc gcccggactg gagccctgac attgctgcgc tcggggggct ccaggcagcc      240

cgtatcgggg cctttatttc tcgtcggcgg cgccctgcac cgcgcctcgc aaagccaaac      300

accagagcac cctagaaggt ttaactaaaa gaatgctcat gtttgaccca gttcctgtca      360

agcaagaggc catggaccct gtctcagtgt catacccatc taattacatg gaatccatga      420

agcctaacaa gtatggggtc atctactcca caccattgcc tgagaagttc tttcagaccc      480

cagaaggtct gtcgcacgga atacagatgg agccagtgga cctcacggtg aacaagcgga      540

gttcaccccc ttcggctggg aattcgccct cctctctgaa gttcccgtcc tcacaccgga      600

gagcctcgcc tgggttgagc atgccttctt ccagcccacc gataaaaaaa tactcacccc      660

cttctccagg cgtgcagccc ttcggcgtgc cgctgtccat gccaccagtg atggcagctg      720

ccctctcgcg gcatggaata cggagcccgg ggatcctgcc cgtcatccag ccggtggtgg      780

tgcagcccgt cccctttatg tacacaagtc acctccagca gcctctcatg gtctccttat      840

cggaggagat ggaaaattcc agtagtagca tgcaagtacc tgtaattgaa tcatatgaga      900

agcctatatc acagaaaaaa attaaaatag aacctgggat cgaaccacag aggacagatt      960

attatcctga agaaatgtca ccccccttaa tgaactcagt gtcccccccg caagcattgt     1020

tgcaagagaa tcacccttcg gtcatcgtgc agcctgggaa gagaccttta cctgtggaat     1080

ccccggatac tcaaaggaag cggaggatac acagatgtga ttatgatgga tgcaacaaag     1140

tgtacactaa aagctcccac ttgaaagcac acagaagaac acacacagga gaaaaaccct     1200

acaaatgtac atgggaaggg tgcacatgga agtttgctcg gtctgatgaa ctaacaagac     1260

atttccgaaa acatactgga atcaaacctt tccagtgccc ggactgtgac cgcagcttct     1320

cccgttctga ccatcttgcc ctccatagga aacgccacat gctagtctga ttgcctctgt     1380

gtcctgcctc agcgtgactc cccactcacc tggctctctc tctgtcctgc ctcccattat     1440

ctaacacatt ttttacatgt acattttaat ttgattcagc tggtctgaat ctctgaattt     1500

atatcatcca aaacttccat atggtcagta gtagatgttc tctaatcctc cctctcctta     1560

ccacgggtca gacctaaaga atgtgaacac tttttttttt ttttctgggg atgctaagca     1620

aacccttctt acagatacgt ttaatgtaat aagaacaagg gaacatgtaa actaacataa     1680

ccaattgtca gttctccatg tattcctcaa aagaatgtca gagtaaatgt attagaaata     1740

cagtatccag actgctagtc cttgccagag acattcttac ctctgccctg tgataatatt     1800

ttatgcttga cagtgaaaac aagtgtggcc ccttgcaccg gttagctaga agtacagcca     1860

gatttcaagc tagtgcagtc acctcttccg tcattcttca caaatcttgt caacctggat     1920

cttagacttc atctgaatcg agttctttgc cctcctttgt gcctgcagct catatggagg     1980

tctttgccac caatgggaga tgagcccaaa ctttcgatct aggtgggtga tgtgtagcag     2040

ttcaagggaa gggtgctgtg ttttcatagc atggagtcgg aggagagggc catttagcag     2100

ggggagcaga agaggcaatt cctcctgggc taggggttgt cagtgaggtt tcaacatttt     2160

gttagctgtg tgcagcattc ccagagcttc agtctctgtg catactcagc tttgtagaac     2220

catgctgcaa agccatatac cgatggggtt atccatgcaa ctatctccat tcctacaatg     2280

tccttaatat gagatcatca aacattgata gtagggactc catggaatat ttgcccagta     2340

atggtaagaa atctttcggg taagagtatg gatggttctt cttttaccca atctgcttat     2400

agcttttttt gtaaacaggg aaatgttgag tggtacttgt attcccttat caaattaatc     2460

acatagcttt tatacagaaa ctcttcctgt gtgagctgtt aaggtgccaa attggctgtc     2520

atttgtattc atgacacata ccataaagca tctgctaatg ctttaatgga ttgattcaat     2580

taagacctga gtgacactat ttgtaaatat aactagttgt gaagcacaca tacctttatt     2640

ttgggaattt atgagaaaat atagaaaacc acagatcagg gattcatata tgtagctcaa     2700

aaattcccaa aagtttactg ttagagttgg caatttccta tcactatttc agtgtcagaa     2760

caaactgaaa ataatggctc gtgtttatgt tgaagataaa tagcaccatt attgggggaa     2820

gttattcaaa agcaggcttt tgagcaccat agtctaaatg ccaataaaaa taattcatac     2880

atagaaatgt cattggtcct gaatttgaag aaagtgagca acagtagtta aatgtgggtg     2940

catataacca aattcccctt catcaagaat ggaggagaag agagaagaat gaaatcctga     3000

agattcatcc cagccgcaac tcaggatcca acacaacttt aactgggagg aatacattgt     3060

ttgatcattt ttaaaacatc tgtgaatgag tgattccgga ggcctgtgaa ttgtgtgggg     3120

agcttgcttt gatggcactg tgttaataaa agttgtaggg actgtgcacc taagaggcta     3180

agaggtccca ctcatccgcc ctgtgaacca gctgtaaaga aatgtagtta agaaatgcaa     3240

agaaatgtgt tatcttggca cttgggtttg attttccttt ttttaaagca ctgcaaaact     3300

tctttaggat actaaaacat cctaattggg ctgttttttt gttttgtttt gtttttcagc     3360

taaaggcaaa gataattttt ttttcagctg aagtttttct tttttgcaac tatgacatga     3420

attgagtgat aaaatggctc tttgaaaagt agatattgtc tgtattgtaa atgcttagtc     3480

atattcatgg caaagtgttc atttcttgag atggttcttt cacaacacac aagaatcaag     3540

atggaacgca aggaaaatct ttttgttttg accgaggtaa ccagtttatg tgtgttccaa     3600

tccatagaga agtgggggaa agggcgagaa aggatcagat tgatctggga tcagctttga     3660

gcctgagttc agtgaatagc ctcatgggca tctcatggaa ttgatgcatt tgctgtggca     3720

tatttaaatt ttgttcaaaa gatttgaagc aagaccttgc aaagactctt aacattactg     3780

ttcagcttgc ttagattgtg ttaacagttc atttaacaaa gatccgtttt aactctgaac     3840

aaaagcaacc cagagcggcc attctctatt cccatgctgg tcaatacgct ttcattacca     3900

attggccctt accaaacttt tcttatatat atatttgtat tttactatga tagttgagaa     3960

atttagcctc ttagtcattt ttagctgtta ttgtggaaga cctcaaatac aagattagat     4020

gcccttgaac atgttttaat gatgtgtgtc atgttactat caatggtgat ttcaatcgca     4080

atattttaaa ttgatgagaa tgatttgtaa acatgaagtt actattacgt aaattctgtt     4140

tgttatagag tttcttcagt tgttacccaa gtgtcatcct agagaagtca gaagaatcag     4200

aatccatcgt attttagagt tatgtgaatc tacatcataa atgggcatta acattctaaa     4260

ttgcttggtt tggagaatgt gttagcagca tagctatatt caactaggga gatgctaaat     4320

acacagaagt ttcaagagcc ttggaacaga attacagggg aactatatat gtatatgtat     4380

attttattaa acacccatct gcactatcag tattgcacta atgtggaatt tgaaagacta     4440

ttttgctgat actgtatata tgcgcatcat tcctgattag attgttgtaa agacaatctg     4500

aaagatctaa ggttttaaaa taatttggtt tgaaaatata cagttgtctt gaaggaattg     4560

ctgtcataca tgaagttgct ccgagctgtc tttattctct tcttggtcaa ggttaacaat     4620

tgctaaatga tcgcaaattc acctaaacaa tacatttaca aagccatctt tacatgcatt     4680

aaacgagggc tacaacaata ttgttttaca aatactagca cttttttttc tgttatgtac     4740

ttagtgttag agggtcaaaa taatctttct gcttagcatc tcttaaacca tacctgcaaa     4800

tatagcagga ttattacatt tacagtactt taatacttgt ataaactatg cagaaatttt     4860

taataaagtg taatatattt tataagctaa taagactgaa tgggtaaagg tttttagcat     4920

gcattagtat acttgcagat actgaaacat tttggtaatc tttcttacta aagatgtgaa     4980

tgtttaatgt accttctctg tttctactct gtagtccaat gggaattcag taatgacatt     5040

ttgtcatgtc aaactgtgaa cataaatttg tactgtacag tcctcatata ctatatacag     5100

tatgcaatat atattatata cttgttaata aaaccatcag aatattaaat gtgatcatgt     5160

gattacttca tatgcagtga tcactagagc aaaacttaca gagcaatgta agaacccttg     5220

cttagaacat tacttactct gatgggcagt tattgttgat ggagggacag aaaaatagat     5280

ctaactggaa gatgaactac cggaattaac tcagccctca agctatgtcc ctggttttct     5340

gaaaacagcc aacaggaagt ctcctaggct gaaatcataa aactgcagac aatccagcaa     5400

aaatctacaa actcacctag ttcattcttg aaatacttct tgtatttgtt atttatgaac     5460

ccctgcctgc ttccaaaaag aacttgcagc attttgtatt aaaagacgca tgtgtataat     5520

actttaaact tttagagtaa aatatcaaga ctctcatgtt ggggagtggg gaacgaggaa     5580

cagaacaata acgcattaaa gtaaataact ctggaaaaaa aaaaaaaaaa aa             5632


<210>  340
<211>  4339
<212>  DNA
<213>  homo sapiens

<400>  340
cctagacaaa ggggccggcg cggcggagca gactggtgca gcctgggccg cgcgctcaga       60

gcgctgggcg tctgggcagc tgagtgggca gagctgaccc ggtgcgggtg ggagtcaggg      120

cgcccggaaa acccggctct gggtagcaga ccccgcccgg gctggctcgg cgccgggcct      180

tcgggcttcc actcagtctt tgaccctcgg tcctcgctca gcggcccggc aggccgcaca      240

actgtaaccg ctgccccggc cgccgcccgc tccttctcgg tccggcgggc acagagcgca      300

gcgcggcggg gccggcggca tggctgtgtc ctggaggagc tggctcgcca acgaaggggt      360

taaacacctc tgcctgttca tctggctctc catgaatgtc ctgcttttct ggaaaacctt      420

cttgctgtat aaccaagggc cagagtatca ctacctccac cagatgttgg ggctaggatt      480

gtgtctaagc agagcctcag catctgttct taacctcaac tgcagcctta tccttttacc      540

catgtgccga acactcttgg cttacctccg aggatcacag aaggttccaa gcaggagaac      600

caggagattg ttggataaaa gcagaacatt ccatattacc tgtggtgtta ctatctgtat      660

tttctcaggc gtgcatgtgg ctgcccatct ggtgaatgcc ctcaacttct cagtgaatta      720

cagtgaagac tttgttgaac tgaatgcagc aagataccga gatgaggatc ctagaaaact      780

tctcttcaca actgttcctg gcctgacagg ggtctgcatg gtggtggtgc tattcctcat      840

gatcacagcc tctacatatg caataagagt ttctaactat gatatcttct ggtatactca      900

taacctcttc tttgtcttct acatgctgct gacgttgcat gtttcaggag ggctgctgaa      960

gtatcaaact aatttagata cccaccctcc cggctgcatc agtcttaacc gaaccagctc     1020

tcagaatatt tccttaccag agtatttctc agaacatttt catgaacctt tccctgaagg     1080

attttcaaaa ccggcagagt ttacccagca caaatttgtg aagatttgta tggaagagcc     1140

cagattccaa gctaattttc cacagacttg gctttggatt tctggacctt tgtgcctgta     1200

ctgtgccgaa agactttaca ggtatatccg gagcaataag ccagtcacca tcatttcggt     1260

cataagtcat ccctcagatg tcatggaaat ccgaatggtc aaagaaaatt ttaaagcaag     1320

acctggtcag tatattactc tacattgtcc cagtgtatct gcattagaaa atcatccatt     1380

taccctcaca atgtgtccaa ctgaaaccaa agcaacattt ggggttcatc ttaaaatagt     1440

aggagactgg acagaacgat ttcgagattt actactgcct ccatctagtc aagactccga     1500

aattctgccc ttcattcaat ctagaaatta tcccaaggat gactggaaac catacaagct     1560

tagaagacta tactttattt gggtatgcag agatatccag tccttccgtt ggtttgcaga     1620

tttactctgt atgttgcata acaagttttg gcaagagaac agacctgact atgtcaacat     1680

ccagctgtac ctcagtcaaa cagatgggat acagaagata attggagaaa aatatcatgc     1740

actgaattca agactgttta taggacgtcc tcggtggaaa cttttgtttg atgaaatagc     1800

aaaatataac agaggaaaaa cagttggtgt tttctgttgt ggacccaatt cactatccaa     1860

gactcttcat aaactgagta accagaacaa ctcatatggg acaagatttg aatacaataa     1920

agagtctttc agctgaaaac ttttgccatg aagcaggact ctaaagaagg aatgagtgca     1980

atttctaaga ctttgaaact cagcggaatc aatcagctgt gttatgccaa agaatagtaa     2040

ggttttctta tttatgatta tttaaaatgg aaatgtgaga atgtggcaag atgaccgtca     2100

cattacatgt ttaatctgga aaccaaagag accctgaaga atatttgatg tgatgattca     2160

cttttcagtt ctcaaattaa aagaaaactg ttagatgcac actgttgatt ttcatggtgg     2220

attcaagaac tccctagtga ggagctgaac ttgctcaatc taaggctgat tgtcgtgttc     2280

ctctttaaat tgtttttggt tgaacaaatg caagattgaa caaaattaaa aattcattga     2340

agctgaaatt ccattttctg tgttgtgtat aaacagagta gctttaattt gcaagcactc     2400

caggcaaata tattagatgt ttgaaaacac agcacaagac tctgtattga tacgggtact     2460

ttgtgtcaat atctaatcgt ctccactact tatgctaata cctctatttg atatctgaag     2520

actatatgct aactgaacct tcctcaaatg ttgttatagt atctattttt atatattttt     2580

ttctttttat tcctctctct agggaaatat gccttccctt agcatgcatt agacataatg     2640

atttaatagg tccctttcat cttcatttaa atctatcact attgcatggt aatgaaaata     2700

ttcctactat aaattataaa gggatatata tatatggata tatatatgta tatacacata     2760

tatatataca cacacacaca catatatata tatatatata tatatacaca tatactaata     2820

acttttccct tttttcagca tttttgtctc tattattatt attgtttttt tcccaggtag     2880

ggtttgtctt aggctgtagc ctctaaggat agttagttaa tttgcacttt gagaccaaag     2940

gacatcatgt gtgtcagtag ggactgaata taagatttat ctcctttgcc acacattggt     3000

ttatgatgga gacattgaaa gtctagtcat attcctgaac agtaaaacct gtattttacc     3060

ttttaagtaa gaggaaatat gatattctta ttcaaactta agtttagaat ccagaatatt     3120

actgtcgcac tttttggtat cctgagtttc catagggaac tattgggttt aaagtcaccg     3180

ttggaactac actgtgtgat cttataaact tatgttccct ggctatcata ttcttggctc     3240

agaacaatat ttcccattac tatcttaaga attaaggcat tcatggctca cgcctgtaat     3300

cccggcactt tgggaggcca aggcaggtgg atcacgaggt cagagttcaa gaccagcctg     3360

accaagttgg tgaaacccca tcgctactaa aaatacaaat attaggcggg tgtggtggcg     3420

ggtgcctata atcccaacta ctcgggagac tgaggcaaag aatcgcttga acccggtggg     3480

cggaggttgc agtgagccaa gattgcacca ctgcactcca gcctgggtga cagagcaaga     3540

ttccatctca aaaaaaaaaa aaaaaaaaaa aaaaaagaat taaagcattc atacagttta     3600

gtgattttgt ttagtagtcg gctatcaatt gctatcaaat ataacactgc tgaaatcagc     3660

agtgtgactt accttgccat tgttaaaatg ttacataaaa cataacatga tagatgctaa     3720

ggcctttttt tgctataatt caccaatagc aatcaagcat gctaacccat actgaatgat     3780

atttacttgt agatatttct tcctttcctt gaaattctcc tttctatgga aagaagatga     3840

acccaaaaaa gtgataggaa atgtggaatg ctcatgcaga tttagctctg aaggcatatt     3900

taataactag tatgtcttga caacagtctt tagattaaaa agaattttca tggaaacatt     3960

taacagaaag aactagtaaa aagacacttt gagttagtcc aggcttaatg tgcaatactg     4020

actctatact gatcataatt tatttatgcg atcatattaa tagacctaat ttcattaaaa     4080

caggtagaag atttttcaaa agaaagatga tgtttcaaag ctggtctgcc attctagatg     4140

agcctccttg cttatttaag ttccagtagg tgttcaaatg ttaaatgtta aacataggtc     4200

atctttgctt ctgcagggct tcatcttgca tgtttaagag aactttgttt tattttgagg     4260

gattatttct ctggggatca ttcttataat acaagcctta aatcactaat tttagtagca     4320

ataaatgtta aaattgaaa                                                  4339


<210>  341
<211>  5507
<212>  DNA
<213>  homo sapiens

<400>  341
gcggccgcgg gctctcgcgg ggcggcgacg ccgcggggag gatgctgctt gccgcgcccg       60

cgtcctcacc gtcctcccgg gccgcctgct ggggctttgt tgtggcccgg acgccgcggg      120

ccaccccctg aagtcgcctg ccgccgccgc cgccgcacct agcggacggg cgggcgggcg      180

cgcgtgtgcc caggagtgcg cgcctgtcgc ggtggtgggt gcaggactgg acccacgggc      240

ccattgtgcg cccgcccgcg gcagccagga ccatgtgggt gaacccggag gaggtgttgc      300

tggccaacgc gctgtggatc accgagaggg ccaacccata cttcatcctg cagcggagga      360

agggccacgc cggcgatgga ggcggcggcg gcggactggc gggcctgctg gtgggtaccc      420

ttgatgttgt gttggactcc agcgcccggg tcgctcctta ccgaatcttg taccagactc      480

cagactccct ggtctactgg accatcgcct gtggtggttc caggaaagaa atcactgaac      540

actgggaatg gcttgagcaa aatctcttgc agacactctc catctttgaa aatgagaatg      600

atatcaccac atttgtgaga ggaaaaatac agggcatcat tgcagaatac aacaaaatca      660

atgatgtaaa ggaagatgat gacacggaga agtttaaaga agccattgtg aaatttcata      720

ggctgtttgg gatgccagag gaagagaaac tcgtcaacta ttactcttgc agctattgga      780

aggggaaggt cccccgtcag ggttggatgt acctcagcat taaccacctt tgcttttatt      840

cttttcttat gggaagggaa gcgaaactgg tcatccggtg ggtagacatc actcagcttg      900

agaagaatgc caccctgctt ctgcctgatg tgatcaaagt gagcacacgg tccagtgagc      960

atttcttctc tgtattcctc aacatcaacg agaccttcaa gttaatggag cagcttgcca     1020

acatagccat gaggcaactc ttagacaatg agggatttga acaagatcga tccctgccca     1080

aactcaaaag gaaatctcct aaaaaagtgt ctgctctaaa acgtgatctt gatgccaggg     1140

caaagagtga gagataccgt gcacttttcc ggctgcccaa agatgaaaaa ttagatggcc     1200

acacagactg cactctctgg actccattta acaaaatgca cattttgggg cagatgtttg     1260

tgtccacaaa ttacatctgt tttaccagca aggaggagaa cttatgtagc ctcattatcc     1320

cgctccgtga ggtgacaatt gtggaaaagg cagacagctc cagtgtgctc cccagtccct     1380

tatccatcag cacccgaaac aggatgacct tcctatttgc caacttgaaa gatagagact     1440

ttctagtgca gaggatctca gatttcctgc aacagactac ttccaaaata tattctgaca     1500

aggagtttgc aggaagttac aacagttcag atgatgaggt gtactctcga cccagcagcc     1560

tcgtctcctc cagcccccag agaagcacga gctctgatgc tgatggagag cgccagttta     1620

acctaaatgg caacagcgtc cccacagcca cacagaccct gatgaccatg tatcggcggc     1680

ggtctcccga ggagttcaac ccgaaattgg ccaaagagtt tctgaaagag caagcctgga     1740

agattcactt tgctgagtat gggcaaggga tctgcatgta ccgcacagag aaaacgcggg     1800

agctggtgtt gaagggcatc ccggagagca tgcgtgggga gctctggctg ctgctgtcag     1860

gtgccatcaa tgagaaggcc acacatcctg ggtactatga agacctagtg gagaagtcca     1920

tggggaagta taatctcgcc acggaggaga ttgagaggga tttacaccgc tcccttccag     1980

aacacccagc ttttcagaat gaaatgggca ttgctgcact aaggagagtc ttaacagctt     2040

atgcttttcg aaatcccaac atagggtatt gccaggccat gaatattgtc acttcagtgc     2100

tgctgcttta tgccaaagag gaggaagctt tctggctgct tgtggctttg tgtgagcgca     2160

tgctcccaga ttactacaac accagagttg tgggtgcact ggtggaccaa ggtgtctttg     2220

aggagctagc acgagactac gtcccacagc tgtacgactg catgcaagac ctgggcgtga     2280

tttccaccat ctccctgtct tggttcctca cactatttct cagtgtgatg ccttttgaga     2340

gtgcagttgt ggttgttgac tgtttcttct atgaaggaat taaagtgata ttccagttgg     2400

ccctagctgt gctggatgca aatgtggaca aactgttgaa ctgcaaggat gatggggagg     2460

ccatgaccgt tttgggaagg tatttagaca gtgtgaccaa taaagacagc acactgcctc     2520

ccattcctca cctccactcc ttgctcagcg atgatgtgga accttaccct gaggtagaca     2580

tctttagact catcagaact tcctacgaga aattcggaac tatccgggca gatttgattg     2640

aacagatgag attcaaacag agactgaaag tgatccagac gctggaggat actacgaaac     2700

gcaacgtggt acgaaccatt gtgacagaaa cttcctttac cattgatgag ctggaagaac     2760

tttatgctct tttcaaggca gaacatctca ccagctgcta ctggggcggg agcagcaacg     2820

cgctggaccg gcatgacccc agcctgccct acctggaaca gtatcgcatt gacttcgagc     2880

agttcaaggg aatgtttgct cttctctttc cttgggcatg tggaactcac tctgacgttc     2940

tggcctcccg cttgttccag ttattagatg aaaatggaga ctctttgatt aacttccggg     3000

agtttgtctc tgggctaagt gctgcatgcc atggggacct cacagagaag ctcaaactcc     3060

tgtacaaaat gcacgtcttg cctgagccat cctctgatca agatgaacca gattctgctt     3120

ttgaagcaac tcagtacttc tttgaagata ttaccccaga atgtacacat gttgttggat     3180

tggatagcag aagcaaacag ggtgcagatg atggctttgt tacggtgagc ctaaagccag     3240

acaaagggaa gagagcaaat tcccaagaaa atcgtaatta tttgagactg tggactccag     3300

aaaataaatc taagtcaaag aatgcaaagg atttacccaa attaaatcag gggcagttca     3360

ttgaactgtg taagacaatg tataacatgt tcagcgaaga ccccaatgag caggagctgt     3420

accacgccac ggcagcagtg accagcctcc tgctggagat tggggaggtc ggcaagttgt     3480

tcgtggccca gcctgcaaag gagggcggga gcggaggcag tgggccgtcc tgccaccagg     3540

gcatcccagg cgtgctcttc cccaagaaag ggccaggcca gccttacgtg gtggagtctg     3600

ttgagcccct gccggccagc ctggcccccg acagcgagga acactccctt ggaggacaaa     3660

tggaggacat caagctggag gactcctcgc cccgggacaa cggggcctgc tcctccatgc     3720

tgatctctga cgacgacacc aaggacgaca gctccatgtc ctcatactcg gtgctgagtg     3780

ccggctccca cgaggaggac aagctgcact gcgaggacat cggagaggac acggtcctgg     3840

tgcggagcgg ccagggcacg gcggcactgc cccggagcac cagcctggac cgggactggg     3900

ccatcacctt cgagcagttc ctggcctccc tcttaactga gcctgccctg gtcaagtact     3960

ttgacaagcc cgtgtgcatg atggccagga ttaccagtgc aaaaaacatc cggatgatgg     4020

gcaagcccct cacctcggcc agtgactatg aaatctcggc catgtccggc tgacacgggc     4080

gccttcccgg gggagtggga ggagagggag gggagggatt ttttatgttc ttctgtgttg     4140

agttttttct ttctttcttt taaattaaat atttattagt acctggcttg aagcctagtg     4200

ttttcataat gtaattcaat gaaaactgtt ggagaaatat ttaaacacct caatgtaggt     4260

acattacact cttgttgcgg ggaggggatt taccagaata cagtttattt cgtgaattct     4320

aaaaaacaaa aagatgaatc tgtcagtgat atgtgtgtat tataacttat taatcttgct     4380

gttgagctgt atacatggtt taaaaaatag tactgtttaa tgctaagtaa ggcagcagtc     4440

atttgtgtat tcaggctttt taaataaaat tagagctgta aggaaaatga aaagccacaa     4500

atgcaagact gttcttaaat ggaaggcata gtcagcgagg gtaaatccta taccacttta     4560

ggaagtatta aaaatatttt taagatttga aatatatttc atagaagtcc tctattcaaa     4620

atcatattcc acagatgttc cccttcaaag ggaaaacatt tggggttcta aacagttatg     4680

aaagtaagtg atttttacat gattccagaa taacacttgt attgaccaat ttagacagat     4740

accagaccaa ttttgcattt aagaaattgt tctgattatt tacgtcaact cattagaatt     4800

cagtgaaaag taacagtctt ttgtcacaga gaatctgaaa gtagcagcaa agacagaggg     4860

ctcatgacag gtttttgctt ttgctttgct tttgtttttg aaagagtaaa agtactgatg     4920

cttctgatac tggatgttta gcttcttact gcaaaaacat aagtaaaaca gtcaacttta     4980

ccatttccgt attctccata gattgaagaa atttatacca catatcgcat atgaccatct     5040

ttccatcaaa tcaatgtaga gataatgtaa actgaaaaaa aatctgcaag ataatgtaac     5100

tgaatgtttt aaaaacagaa cttgtcactt tatataaaag aatagtatgc tctatttcct     5160

gaatggatgt ggaaatgaaa gctagcgcac ctgcactttg aattcttgct tcttttttat     5220

tactgttatg attttgcttt ttacagatgt tggacgattt tttcttctga ttgttgaatt     5280

cataatcatg gtctcatttc ctttgcttct ttggaatatt tctttcaaca cattccttta     5340

ttttattata cattgtgtcc tttttttagc tattgctgct gttgtttttt attctattta     5400

caggatgatt tttaaactgt caaatgaagt agtgttaacc tcaaataggc taaatgtgaa     5460

caaataaaat acagcaaata ctcagaaaaa aaaaaaaaaa aaaaaaa                   5507


<210>  342
<211>  3224
<212>  DNA
<213>  homo sapiens

<400>  342
attccagatg cctgggccga ctcgaagccc ttataaggcg cggagacacc ggctctggct       60

gggccgcccg cctccacagc cgccgcccag ggttctcccg ccactgccgc ccgcaccccc      120

gcccccgcgg ggttaagatc acacacgcgc ccacgccggc ccgcggggcg tgcactttcg      180

ctgggttccg tccgccgcag cccaaacagt gctcttacag cctgttccaa gtgtggctta      240

atccgtctcc accaccagat ctttctccgt ggattcctct gctaagaccg ctgccatgcc      300

agtgacggta acccgcacca ccatcacaac caccacgacg tcatcttcgg gcctggggtc      360

ccccatgatc gtggggtccc ctcgggccct gacacagccc ctgggtctcc ttcgcctgct      420

gcagctggtg tctacctgcg tggccttctc gctggtggct agcgtgggcg cctggacggg      480

gtccatgggc aactggtcca tgttcacctg gtgcttctgc ttctccgtga ccctgatcat      540

cctcatcgtg gagctgtgcg ggctccaggc ccgcttcccc ctgtcttggc gcaacttccc      600

catcaccttc gcctgctatg cggccctctt ctgcctctcg gcctccatca tctaccccac      660

cacctatgtc cagttcctgt cccacggccg ttcgcgggac cacgccatcg ccgccacctt      720

cttctcctgc atcgcgtgtg tggcttacgc caccgaagtg gcctggaccc gggcccggcc      780

cggcgagatc actggctata tggccaccgt acccgggctg ctgaaggtgc tggagacctt      840

cgttgcctgc atcatcttcg cgttcatcag cgaccccaac ctgtaccagc accagccggc      900

cctggagtgg tgcgtggcgg tgtacgccat ctgcttcatc ctagcggcca tcgccatcct      960

gctgaacctg ggggagtgca ccaacgtgct acccatcccc ttccccagct tcctgtcggg     1020

gctggccttg ctgtctgtcc tcctctatgc caccgccctt gttctctggc ccctctacca     1080

gttcgatgag aagtatggcg gccagcctcg gcgctcgaga gatgtaagct gcagccgcag     1140

ccatgcctac tacgtgtgtg cctgggaccg ccgactggct gtggccatcc tgacggccat     1200

caacctactg gcgtatgtgg ctgacctggt gcactctgcc cacctggttt ttgtcaaggt     1260

ctaagactct cccaagaggc tcccgttccc tctccaacct ctttgttctt cttgcccgag     1320

ttttctttat ggagtacttc tttcctccgc ctttcctctg ttttcctctt cctgtctccc     1380

ctccctccca cctttttctt tccttcccaa ttccttgcac tctaaccagt tcttggatgc     1440

atcttcttcc ttccctttcc tcttgctgtt tccttcctgt gttgttttgt tgcccacatc     1500

ctgttttcac ccctgagctg tttctctttt tcttttcttt tttttttttt ttttttttta     1560

agacggattc tcactctgtg gcccaggctg gagtgcagtg gtgcgatctc gactcactgc     1620

aacccccgcc tcctgggttc aagcgattct cctgccccag cctcccaagt agctgggagg     1680

acaggtgtga gctgccgcac ccagcctgtt tctctttttc cactcttctt ttttctcatc     1740

tcttttctgg gttgcctgtc ggctttctta tctgcctgtt ttgcaagcac cttctcctgt     1800

gtccttggga gccctgagac ttctttctct ccttgcctcc acccacctcc aaaggtgctg     1860

agctcacatc cacacccctt gcagccgtcc atgccacagc cccccaaggg gccccattgc     1920

caaagcatgc ctgcccaccc tcgctgtgcc ttagtcagtg tgtacgtgtg tgtgtgtgtg     1980

tgtgtgtgtg tgtgtgtttg gggggtgggg ggtgggtagc tggggattgg gccctctttc     2040

tcccagtgga ggaaggtgtg cagtgtactt cccctttaaa ttaaaaaaca tatatatata     2100

tatatttgga ggtcagtaat ttccaatggg cgggaggctt taagcaccga ccctgggtcc     2160

ctaggccccg cctggcactc agccttgcca gagattggct ccagaatttt tgccaggctt     2220

acagaacacc cactgcctag aggccatctt aaaggaagca ggggctggat gcctttcatc     2280

ccaactattc tctgtggtat caaaaagaaa aaaaaaaaaa aagaaggagt cggggccggg     2340

cgtggtggct cacgcctgta atcccagcac tttgggagac caagtcaggc aatcatctga     2400

agtcaggagt tcaagaccag cctggccaac atggtgaaag catgtctcta ttaaaaatac     2460

aaaaattagc cgggcgtggt ggcgggcgcc tgtaatccca ggtatttggg gggactgaga     2520

caggagaatc ccttcaaccc gggaggtgga ggttgcagta agtcaagatg gcaccactgt     2580

gctccagcct gggggacaga gcgagactcc atctcaaaaa aaaaaaggaa tcggacgaag     2640

aaccacagga tgttgaagac aactgtctga agtatttgtg agggacagcg atgtggccct     2700

ctgtgttaag aataacgtgt cctgctttgg cagagagaag aaaatagcca ctgcccgctt     2760

tcaaggcaag atcgaccttt tctgttttgt tttgtttttc tttctttttc ctggccatga     2820

ggacaaaaat tactgagtgg cccttaaaga gggaagtttg ttttcagctg ttctcttttg     2880

cccgtaggtg ggagggtggg gattgctgcg tcctagctag aggaatggct ttgcttgaat     2940

gtgtagtgca cacgcacggg tgtttctgtg tgctagttgc ttcttgctgc tgcttcctgc     3000

ttgtctggga ctcacataca taacgtgata tatatatata tatatataaa tgtataaata     3060

tatattttat ttttttttaa atccctggag cttctggttc ctatcagttc ctgttgttaa     3120

tcgtagaacc gttgtccctt cccccattcc cgtatccatc atgttctttt tcttttaaat     3180

atcaatataa aggtaaaaga aaaaaaaaaa aaaaaaaaaa aaaa                      3224


<210>  343
<211>  3649
<212>  DNA
<213>  homo sapiens

<400>  343
aaggaggagt gcactggccg ggatcggtgc agcgctcaca ctcactcaca gtcactctct       60

ctgagcgcgt ctcgctcgct ctcatacacg cccggagccc aggagcgctc aggatcccga      120

gcgccgcgaa aaagttcccc cggcttttgc tggagactca tcgctttggg aagtgcattt      180

gcttcgtggc tccgccgagc ctgctgaatc ctgtcctcgc ggctcgggac cccgggatcg      240

ctgaccgctg ccgccgccgc ctctgcctcc cggactatcg gcagcctcgg caacaatagt      300

ggcggccgcc cccagcgagg ctccgggagc ccttgcctgc gggggtccgg ggactcgagc      360

cggcctccgc ctcccggacg cacagccagc gtggtccccg cgtgcaacgc gagcgccggg      420

gagtggctcc tgctttgccc ctcgtggggg ccgagccaag accagtctgc aaactccatc      480

ccgccggctg gaagaagtcg cggagccggc accaaacccg cagcgtcttc ccgcgcggat      540

cccgggactt aaaaagccgg ggccaccccg gcccaggacg ggatgcgggt cggtccggtg      600

cgctctgcca tgagcggcgc ctcgcagccc cgcggcccgg ccctgctctt cccagccacc      660

cgaggcgtcc cggccaaacg cctgctggac gccgacgacg cggcggctgt ggcggccaag      720

tgcccgcgcc tctccgagtg ctccagcccc ccggactacc tcagcccccc cggctcgccc      780

tgcagcccgc agcccccgcc tgccgctccg ggggccggcg gaggctccgg gagcgcgccg      840

gggcccagcc gcatcgccga ctacctgctg ctgcccctag ccgagcgcga gcatgtgtcc      900

cgggcgctgt gcatccacac tggacgcgag ctgcgctgca aggtgtttcc cattaaacac      960

taccaggaca aaatcaggcc ttacatccag ctgccatcgc acagcaacat tactggcatt     1020

gtggaagtga tccttgggga aaccaaggcc tatgtcttct ttgagaagga ctttggggac     1080

atgcactcct atgtgcgaag ccggaagagg ctgcgggaag aggaagccgc ccggctcttc     1140

aagcagattg tctccgccgt cgcccactgc caccagtcag ccatcgtgct gggggacctg     1200

aagcttagga agttcgtctt ctccacggag gagagaaccc agcttagact agaaagtcta     1260

gaagacacac acataatgaa gggggaagat gatgctttgt cagacaaaca tggctgccca     1320

gcctacgtga gccctgagat cctcaacacc actgggacct actccggaaa ggctgcggac     1380

gtttggagcc tgggggtgat gctctacacc cttctggttg gacgataccc cttccatgac     1440

tcagacccca gtgccctttt ctccaaaatt cggcgtggac agttctgcat tcctgagcac     1500

atttccccca aagccaggtg cctcattcgc agcctcttga gacgggagcc ctccgagaga     1560

ctcactgccc ccgagatcct actgcacccc tggtttgagt ccgtcttgga acccgggtac     1620

atcgactcag aaataggaac ttcagaccag attgttccag agtaccagga ggacagtgac     1680

attagttcct tcttctgcta atccccaaaa cctcagaaac ctcataattc ttaacacctg     1740

gcatttccat ttctaaagat ggacaggccc tttggcgtgg taccaaccag ataatgactg     1800

catcaggatg aaagctgctg aactcggcat ggcgcctcct cttctctgtt gggatgagtg     1860

actttattga tttgagcagc atatgctgtg attggctgcc ctgcaaattt gtttccctta     1920

aggaaccctc accaactatc tctgctggat ttgggagttc cgcatctttt gtggagggca     1980

gagtatggac atcttacacc cggtggtcaa gtgtgtaata aacttgagca ttcgaatggg     2040

agaaaaagca aatcgcacaa tgacatattt tgagtaataa ccgtattttt cacagggtga     2100

caaattgggc caataaatct gccatctttg aactcatctt tggtggctag actgctacgg     2160

cagcttctct gatgggaaag ttcctttttt ggcttaacac tcaccctttc ttcacactca     2220

catttaccaa tgactctgct ccgtttttgg agcagactgt tttaagttgc tcaggagcct     2280

gatggaacca tgaaccgaga ctcttctctg tttcctgcca agacctcatc tgcactaatg     2340

ccttctccct gaccttgaca cttccccctt tagctataaa agcacttacc agccgaacgt     2400

ggaacagtat cacaaaagat tccatctccc aacgatttca gaactctgag ctcagagaga     2460

ctccagattt taaaaaataa tttgagtgct tggaaactat tagcttttta agttccttcc     2520

aaatatgtta gtacctaccc tttacttttt ccccaagacc atctcagggt ggagcattct     2580

gtctaagaga agaaagataa ggaggctccc acccacctct cccaagagca gacattaaac     2640

atctttgtgc tttgaagaga gtgaattttg gatagtcttg tgattctcag actaacttcc     2700

agaattatac tttaacccct cccagatatg gtccgccttt ggcattgtgt gtacatctgc     2760

agttttgcat ggtgggttgt taatatttca aatgtgtggt ttatgaatac gtctgtataa     2820

tcggcttctg gagtgaaaca gcaaacccca aatcttcaaa gttggaagga actttaaaaa     2880

tcatccggtc caatctcttt cctctttctg ccacctccca aggcagaaat cccctcttca     2940

gcttcttttg taggtgggaa tccagcctct gttagatatg tccagagatg gaaactcact     3000

cccctacaaa agatggagct taatggagaa attgcaactt tcattaaaaa acaaattcag     3060

atgaaatatc agtaactgtc ttggacagtg ctgaaatcag gtggttaaac gggtaaacaa     3120

aatatactgt attttgagaa atggcacaaa aacaggcagt catctttaag ggctatgcct     3180

aggcaaacta ctaacatgca ttgtgagaat gccgtgtata cctcacgtac tgtgtacttt     3240

gtacatatat tttacctttt atacctatgt tcgattttgt tttgttttgt tttgttctgg     3300

ctttgaggct tgttttgttg tctgtgtctg tctgaataac ctgcgtgtct aaaaccacgt     3360

gaaatgtgaa tgattattgg caatattacc ttgacagaat catgggactt tgagaagagg     3420

gaggacagag gcctctgtcg cactaacgct ctcgtggttg ctcgactgtt gtatctgtga     3480

tacattatcc gactaaggac tctgggctgg cagggccttc tgccgggaaa gctagaaaca     3540

ctaggttctt cctgtacata cgtgtatata tgtgaacagt gagatggccg tttctgactt     3600

gtagagaaat tttaataaac ctggtttcgt aaataaaaaa aaaaaaaaa                 3649


<210>  344
<211>  4004
<212>  DNA
<213>  homo sapiens

<400>  344
agtggcgtcc gttgtaagtg ctatgacaac agggcgaaga tggctcagag ttaggctgga       60

gaggggaggt gtcccttccg ctgcggccgt cgggtttctg ctacatccca ttcaccgcct      120

cctccatcct ttcctcctcg gtgtgagcag caggacttgc atttgttctc gcctgcctag      180

tgtcttccaa gggatagatg ccgtttcctc tgctggtctc tgggggtgac ggggggcgca      240

ggggagcttc ttgggggaat cactccaact ctgtggagct ggtggtgctg cctggtgggg      300

ctctctcttt gcccgggacg tggaacaact ttcagctgga ggacgagagg gaatagtgaa      360

gctaaaggtt gcttttctct gcaccgtccg ttcttgctcc ctctgctcca tcactgggac      420

cttgtcaggc gttcataaag caaaatttgc cgaacgaggg ttcgcagaaa ggtggggcag      480

agctcatctg acgtggcatc agtgtgaaag aaaatgtctt tatttaaagc ccgtgattgg      540

tggtctacta ttctgggaga taaagaagaa tttgatcaag gctgtttgtg tctggctaat      600

gttgacaata gtggaaatgg acaagataaa ataattgtgg gtagctttat gggataccta      660

aggatcttta gcccccatcc tgcaaaaaca ggagatggag ctcaagccga agatttgctt      720

ctagaagtgg atctacgaga tccagtactt caagtggaag taggaaagtt tgtttcaggt      780

accgaaatgc tacatttggc tgtgttacat tctagaaaac tttgtgtcta ctctgtctca      840

ggaaccttgg gtaatgtgga acatgggaac caatgtcaga tgaaattgat gtatgaacat      900

aatcttcaga gaacagcctg caatatgacc tatggatcat ttggtggtgt aaaaggtcga      960

gatttaattt gcatccagtc tatggatggg atgctgatgg tatttgagca ggagagctat     1020

gcttttggaa gatttctccc tggctttctt ctgcctggtc ctcttgccta cagttcccgt     1080

acagattcct tccttactgt ctcttcctgc caacaagtgg aaagttataa gtaccaggta     1140

cttgcttttg caacagatgc agataaaagg caggagactg aacagcaaaa acttggttct     1200

ggaaaaagac tagttgtgga ttggactcta aatattggag agcaagccct tgacatatgt     1260

attgtctctt tcaatcagtc ggcatcctct gtttttgttc ttggtgagag aaactttttt     1320

tgccttaagg ataatggaca aattcgattc atgaagaagc ttgattggag cccaagttgt     1380

tttctgccat attgctcagt ttctgaagga acaataaata ctttgattgg aaatcataat     1440

aacatgctgc atatttatca agatgtgaca ctgaagtggg ccacccaact tccccacatt     1500

cctgtagcag taagagtggg ctgtttgcat gatttaaagg gagtgatagt cactctgagt     1560

gatgatggtc acttgcagtg ttcatacctg gggacagatc cttctctgtt ccaagctcca     1620

aacgttcaat ctcgagaact aaactatgat gaacttgatg tagaaatgaa agaacttcag     1680

aaaatcatca aagatgttaa caaatcacaa ggtgtttggc ccatgactga gagagaagat     1740

gacttgaacg tttctgtcgt ggtttctcct aactttgatt cagtttctca agcgaccgat     1800

gttgaggtgg gaactgacct tgtcccttct gtcacggtga aggtcacact gcagaacaga     1860

gtgatattgc aaaaagccaa attatcagtc tacgtgcaac caccattaga attgacttgt     1920

gatcagttca cctttgaatt tatgacacca gatttgacta gaacagtaag cttttctgtt     1980

tatctgaaaa gaagttatac accatcagaa ttggaaggaa atgctgttgt ttcttattcc     2040

agaccaacag gcattccgcg agttatccaa tgtaaattta gacttcccct aaagttaatt     2100

tgcctaccag gtcagccttc aaaaactgca agccacaaaa ttactattga taccaacaaa     2160

tctccagtca gtcttcttag tctcttccca ggttttgcca gtcagtcaga tgatgatcag     2220

gtgaatgtaa tgggttttca cttcttagga ggtgctcgaa ttactgttct tgcttccaaa     2280

acttctcaac gatatcgcat tcagagtgaa caatttgaag atctttggct cataaccaat     2340

gagcttattc ttcgccttca agaatatttt gaaaaacagg gagtcaaaga ttttgcatgt     2400

tctttttcgg gatctatacc ccttcaagaa tattttgagt tgattgatca tcattttgag     2460

ctacggataa atggtgaaaa attagaagaa ctcttatctg agagagctgt acaatttcgg     2520

gccattcaac gccggctact agcaagattc aaagataaaa ctcctgcccc tcttcaacac     2580

ctggacacct tgttagatgg aacctacaag caggtaattg ctctagcaga tgcagtggag     2640

gaaaaccaag gcaatctgtt ccagtcattc accaggctga agagtgccac ccatttggtg     2700

attctgctga tcgcgctgtg gcagaagctt agtgctgacc aggttgctat tctggaagcg     2760

gcatttctgc cgctacaaga agacactcaa gaattgggct gggaagaaac ggtggatgcc     2820

gccatttccc acctgttgaa gacttgcctg tcgaagagtt ctaaggagca ggctttgaac     2880

ctcaacagcc agctgaacat acccaaagac acaagccaac tgaagaaaca tatcaccttg     2940

ctctgcgata gattatccaa aggtggccgt ctctgcctaa gtaccgatgc agcagcccca     3000

cagaccatgg tcatgccagg tggttgtact acaatcccag agtcagacct agaagaaaga     3060

tcagtagaac aagactctac agaactgttt accaaccaca gacatctcac tgcagagaca     3120

cccaggcctg aagtttcacc cctccaagga gtctcggaat aattcaagta gagttgtttg     3180

gttgagagga acatccccat ctcaaggccg aacctgtgtg aacctcatgc caagcacaga     3240

tatagggctg gcgcaggtgc ttcctaaagc tcaccttcct ggagatgaca tgcatagaaa     3300

gaggggttgg gactttttac ttcactagga gaacttgtaa caccatgggg aagtcagctg     3360

aaacttgtct tgttttgcca ggaaaggaag tagttgcctt tggtcatcca tctgctaata     3420

gtcacagaat acagtgaaat gacatagttt tgggttagat tttataatgc aaagattcag     3480

atccaaaata atttcatacc ccattttttc acagaattct tatatagtaa atgtatcaag     3540

tttaataaag catctcattg tcaaataata tcttggattt tatttataat tagagggatt     3600

tatgagtgat tgctctacat tatttcttca aaggaaagga aaggaattga agactttgct     3660

actctctggt aagacttgaa tgtgattatt ttataaataa aagaaccact atgaaacttt     3720

catgtgattt gttctattaa gctaaacgtg gaagaaggga agttttctag tattgtatga     3780

aaatgtttaa atattttcaa ggaagctagt acattaacat ccccttttca ttaccccatt     3840

gggtggcacc ttttaaaaat ccaggttatt aaaggattca cactttatta cagttaaaat     3900

ttaaggtttt tatgtgtaag aagtgaaaga aactttgcta atttcaagtt cgaattacag     3960

ttgtgagatt gatttattta aataaaaata tgcctttgcc agtt                      4004


<210>  345
<211>  4808
<212>  DNA
<213>  homo sapiens

<400>  345
cggcgtcgcc gcaagagcgc gagaggcgcg gcgggaggag ccggcggcgc gcgcctccct       60

gggcccggac tcggccgcct cccgccgcct cccgcgcggc catggactga gcgccgccgg      120

ccaggccgcg gggatggggc cgccgctccc gctgctgctg ctgctactgc tgctgctgcc      180

gccacgcgtc ctgcctgccg ccccttcgtc cgtcccccgc ggccggcagc tcccggggcg      240

tctggatgga gtgtttggaa ggtgccagaa ggttccggca atggactttt accgctacga      300

ggtgtcgccc gtggccctgc agcgcctgcg cgtggcgttg cagaagcttt ccggcacagg      360

tttcacgtgg caggatgact atactcagta tgtgatggac caggaacttg cagacctccc      420

gaaaacctac ctgaggcgtc ctgaagcatc cagcccagcc aggccctcaa aacacagcgt      480

tggcagcgag aggaggtaca gtcgggaggg cggtgctgcc ctggccaacg ccctccgacg      540

ccacctgccc ttcctggagg ccctgtccca ggccccagcc tcagacgtgc tcgccaggac      600

ccatacggcg caggacagac cccccgctga gggtgatgac cgcttctccg agagcatcct      660

gacctatgtg gcccacacgt ctgcgctgac ctaccctccc gggtcccgga cccagctccg      720

cgaggacctc ctgccgcgga ccctcggcca gctccagcca gatgagctca gccctaaggt      780

ggacagtggt gtggacagac accatctgat ggcggccctc agtgcctatg ctgcccagag      840

gcccccagct ccccccgggg agggcagcct ggagccacag taccttctgc gtgcaccctc      900

aagaatgccc aggcctttgc tggcaccagc cgccccccag aagtggcctt cacctctggg      960

agattccgaa gacccctcca gcacaggcga tggagcacgg attcataccc tcctgaagga     1020

cctgcagagg cagccggctg aggtgagggg cctgagtggc ctggagctgg acggcatggc     1080

tgagctgatg gctggcctga tgcaaggcgt ggaccatgga gtagctcgag gcagccctgg     1140

gagagcggcc ctgggagagt ctggagaaca ggcggatggc cccaaggcca ccctccgtgg     1200

agacagcttt ccagatgacg gagtgcagga cgacgatgat agactttacc aagaggtcca     1260

tcgtctgagt gccacactcg ggggcctcct gcaggaccac gggtctcgac tcttacctgg     1320

agccctcccc tttgcaaggc ccctcgacat ggagaggaag aagtccgagc accctgagtc     1380

ttccctgtct tcagaagagg agactgccgg agtggagaac gtcaagagcc agacgtattc     1440

caaagatctg ctggggcagc agccgcattc ggagcccggg gccgctgcgt ttggggagct     1500

ccaaaaccag atgcctgggc cctcgaagga ggagcagagc cttccagcgg gtgctcagga     1560

ggccctcagc gacggcctgc aattggaggt ccagccttcc gaggaagagg cgcggggcta     1620

catcgtgaca gacagagacc ccctgcgccc cgaggaagga aggcggctgg tggaggacgt     1680

cgcccgcctc ctgcaggtgc ccagcagtgc gttcgctgac gtggaggttc tcggaccagc     1740

agtgaccttc aaagtgagcg ccaatgtcca aaacgtgacc actgaggatg tggagaaggc     1800

cacagttgac aacaaagaca aactggagga aacctctgga ctgaaaattc ttcaaaccgg     1860

agtcgggtcg aaaagcaaac tcaagttcct gcctcctcag gcggagcaag aagactccac     1920

caagttcatc gcgctcaccc tggtctccct cgcctgcatc ctgggcgtcc tcctggcctc     1980

tggcctcatc tactgcctcc gccatagctc tcagcacagg ctgaaggaga agctctcggg     2040

actagggggc gacccaggtg cagatgccac tgccgcctac caggagctgt gccgccagcg     2100

tatggccacg cggccaccag accgacctga gggcccgcac acgtcacgca tcagcagcgt     2160

ctcatcccag ttcagcgacg ggccgatccc cagcccctcc gcacgcagca gcgcctcatc     2220

ctggtccgag gagcctgtgc agtccaacat ggacatctcc accggccaca tgatcctgtc     2280

ctacatggag gaccacctga agaacaagaa ccggctggag aaggagtggg aagcgctgtg     2340

cgcctaccag gcggagccca acagctcgtt cgtggcccag agggaggaga acgtgcccaa     2400

gaaccgctcc ctggccgtgc tgacctatga ccactcccgg gtcctgctga aggcggagaa     2460

cagccacagc cactcagact acatcaacgc tagccccatc atggatcacg acccgaggaa     2520

ccccgcgtac atcgccaccc agggaccgct gcccgccacc gtggctgact tttggcagat     2580

ggtgtgggag agcggctgcg tggtgatcgt catgctgaca cccctcgcgg agaacggcgt     2640

ccggcagtgc taccactact ggccggatga aggctccaat ctctaccaca tctatgaggt     2700

gaacctggtc tccgagcaca tctggtgtga ggacttcctg gtgaggagct tctatctgaa     2760

gaacctgcag accaacgaga cgcgcaccgt gacgcagttc cacttcctga gttggtatga     2820

ccgaggagtc ccttcctcct caaggtccct cctggacttc cgcagaaaag taaacaagtg     2880

ctacaggggc cgttcttgtc caataattgt tcattgcagt gacggtgcag gccggagcgg     2940

cacctacgtc ctgatcgaca tggttctcaa caagatggcc aaaggtgcta aagagattga     3000

tatcgcagcg accctggagc acttgaggga ccagagaccc ggcatggtcc agacgaagga     3060

gcagtttgag ttcgcgctga cagccgtggc tgaggaggtg aacgccatcc tcaaggccct     3120

tccccagtga gcggcagcct caggggcctc aggggagccc ccaccccacg gatgttgtca     3180

ggaatcatga tctgacttta attgtgtgtc ttctattata actgcatagt aatagggccc     3240

ttagctctcc cgtagtcagc gcagtttagc agttaaaagt gtatttttgt ttaatcaaac     3300

aataataaag agagatttgt ggaaaaatcc agttacgggt ggaggggaat cggttcatca     3360

attttcactt gcttaaaaaa aatacttttt cttaaagcac ccgttcacct tcttggttga     3420

agttgtgtta acaatgcagt agccagcacg ttcgaggcgg tttccaggaa gagtgtgctt     3480

gtcatctgcc actttcggga gggtggatcc actgtgcagg agtggccggg gaagctggca     3540

gcactcagtg aggccgcccg gcacacaagg cacgtttggc atttctcttt gagagagttt     3600

atcattggga gaagccgcgg ggacagaact gaacgtcctg cagcttcggg gcaagtgaga     3660

caatcacagc tcctcgctgc gtctccatca acactgcgcc gggtaccatg gacggccccg     3720

tcagccacac ctgtcagccc aagcagagtg attcaggggc tccccggggg cagacacctg     3780

tgcaccccat gagtagtgcc cacttgaggc tggcactccc ctgacctcac ctttgcaaag     3840

ttacagatgc accccaacat tgagatgtgt ttttaatgtt aaaatattga tttctacgtt     3900

atgaaaacag atgcccccgt gaatgcttac ctgtgagata accacaacca ggaagaacaa     3960

atctgggcat tgagcaagct atgagggtcc ccgggagcac acgaaccctg ccaggccccc     4020

gctggctcct ccaggcacgt cccggacctg tggggcccca gagaggggac atttccctcc     4080

tgggagagaa ggagatcagg gcaactcgga gagggctgcg agcatttccc tcccgggaga     4140

ggagatcagg gcgacctgca cgcactgcgt agagcctgga agggaagtga gaaaccagcc     4200

gaccggccct gcccctcttc ccgggatcac ttaatgaacc acgtgttttg acatcatgta     4260

aacctaagca cgtagagatg attcggattt gacaaaataa catttgagta tccgattcgc     4320

catcaccccc taccccagaa ataggacaat tcacttcatt gaccaagatg atcacatgga     4380

aggcggcaca gaggcagctg tgtgggctgc agatttcctg tgtggggttc agcgtagaaa     4440

acgcacctcc atcccgccct tcccacagca ttcctccatc ttagatagat ggtactctcc     4500

aaaggcccta ccagagggaa cacggcctac tgagcggaca gaatgatgcc aaaatattgc     4560

ttatgtctct acatggtatt gtaatgaata tctgctttaa tatagctatc atttcttttc     4620

caaaattact tctctctatc tggaatttaa ttaatcgaaa tgaatttatc tgaatatagg     4680

aagcatatgc ctacttgtaa tttctaactc cttatgtttg aagagaaacc tccggtgtga     4740

gatatacaaa tatatttaat tgtgtcatat taaacttctg atttcacatt caaaaaaaaa     4800

aaaaaaaa                                                              4808


<210>  346
<211>  2542
<212>  DNA
<213>  homo sapiens

<400>  346
gtcacggagc gcttaagagg agggtcgggc tcggccgggg agtcccagtg gcggaggcta       60

cgaaacttgg gggagtgcac agaagaactt cgggagcgca cgcgggacca gggaccaggc      120

tgagactcgg ggcgccagtc cgggcagggg cagcgggagc cggccggaga tgccctgtat      180

ccaagcccaa tatgggacac cagcaccgag tccgggaccc cgtgaccacc tggcaagcga      240

ccccctgacc cctgagttca tcaagcccac catggacctg gccagccccg aggcagcccc      300

cgctgccccc actgccctgc ccagcttcag caccttcatg gacggctaca caggagagtt      360

tgacaccttc ctctaccagc tgccaggaac agtccagcca tgctcctcag cctcctcctc      420

ggcctcctcc acatcctcgt cctcagccac ctcccctgcc tctgcctcct tcaagttcga      480

ggacttccag gtgtacggct gctaccccgg ccccctgagc ggcccagtgg atgaggccct      540

gtcctccagt ggctctgact actatggcag cccctgctcg gccccgtcgc cctccacgcc      600

cagcttccag ccgccccagc tctctccctg ggatggctcc ttcggccact tctcgcccag      660

ccagacttac gaaggcctgc gggcatggac agagcagctg cccaaagcct ctgggccccc      720

acagcctcca gccttctttt ccttcagtcc tcccaccggc cccagcccca gcctggccca      780

gagccccctg aagttgttcc cctcacaggc cacccaccag ctgggggagg gagagagcta      840

ttccatgcct acggccttcc caggtttggc acccacttct ccacaccttg agggctcggg      900

gatactggat acacccgtga cctcaaccaa ggcccggagc ggggccccag gtggaagtga      960

aggccgctgt gctgtgtgtg gggacaacgc ttcatgccag cattatggtg tccgcacatg     1020

tgagggctgc aagggcttct tcaagcgcac agtgcagaaa aacgccaagt acatctgcct     1080

ggctaacaag gactgccctg tggacaagag gcggcgaaac cgctgccagt tctgccgctt     1140

ccagaagtgc ctggcggtgg gcatggtgaa ggaagttgtc cgaacagaca gcctgaaggg     1200

gcggcggggc cggctacctt caaaacccaa gcagccccca gatgcctccc ctgccaatct     1260

cctcacttcc ctggtccgtg cacacctgga ctcagggccc agcactgcca aactggacta     1320

ctccaagttc caggagctgg tgctgcccca ctttgggaag gaagatgctg gggatgtaca     1380

gcagttctac gacctgctct ccggttctct ggaggtcatc cgcaagtggg cggagaagat     1440

ccctggcttt gctgagctgt caccggctga ccaggacctg ttgctggagt cggccttcct     1500

ggagctcttc atcctccgcc tggcgtacag gtctaagcca ggcgagggca agctcatctt     1560

ctgctcaggc ctggtgctac accggctgca gtgtgcccgt ggcttcgggg actggattga     1620

cagtatcctg gccttctcaa ggtccctgca cagcttgctt gtcgatgtcc ctgccttcgc     1680

ctgcctctct gcccttgtcc tcatcaccga ccggcatggg ctgcaggagc cgcggcgggt     1740

ggaggagctg cagaaccgca tcgccagctg cctgaaggag cacgtggcag ctgtggcggg     1800

cgagccccag ccagccagct gcctgtcacg tctgttgggc aaactgcccg agctgcggac     1860

cctgtgcacc cagggcctgc agcgcatctt ctacctcaag ctggaggact tggtgccccc     1920

tccacccatc attgacaaga tcttcatgga cacgctgccc ttctgacccc tgcctgggaa     1980

cacgtgtgca catgcgcact ctcatatgcc accccatgtg cctttagtcc acggaccccc     2040

agagcacccc caagcctggg cttgagctgc agaatgactc caccttctca cctgctccag     2100

gaggtttgca gggagctcaa gcccttgggg agggggatgc cttcatgggg gtgaccccac     2160

gatttgtctt atccccccca gcctggcccc ggcctttatg ttttttgtaa gataaaccgt     2220

ttttaacaca tagcgccgtg ctgtaaataa gcccagtgct gctgtaaata caggaagaaa     2280

gagcttgagg tgggagcggg gctgggagga agggatgggc cccgccttcc tgggcagcct     2340

ttccagcctc ctgctggctc tctcttccta ccctccttcc acatgtacat aaactgtcac     2400

tctaggaaga agacaaatga cagattctga catttatatt tgtgtatttt cctggattta     2460

tagtatgtga cttttctgat taatatattt aatatattga ataaaaaata gacatgtagt     2520

tggaactgaa aaaaaaaaaa aa                                              2542


<210>  347
<211>  5352
<212>  DNA
<213>  homo sapiens

<400>  347
tgattgtgcc tctgcacctc ctcaggtgac cgagggctgg gcaggaggac acagactctt       60

tcatgaagca gtgactagta taggaaaaac agagcctctc tgtagagatg cttaaagtgc      120

tagctttatt taaaaatcag ctggcaaagc gggagtgaag aacacacatt ttcagaagat      180

accggtttcc tgttttcatt aagaaaacag ggaatgcgga acagctgagt gcggcggggg      240

tggtgtcact gcagccggag ggagacctcg ccggtgaaag ctcagcctat ggcatccgag      300

cgtggccggc caagtttaca cgaatgttga aacttctcct cacggggtga ggatcgaggg      360

cgcccgaggc cgggtccggc tgagctggag cgagctgtgc ggggcagcgc gggctggcgg      420

ggagcgcggc gggcgccacg tggaaaagca ggtgatattc tcagtggaga ccaggacaag      480

gaacagaaag acccttactt tgtggagacc ccctatggtt atcaactaga cttagatttc      540

ctcaaatatg tggatgacat acagaaggga aataccatca aaagactgaa catccagaag      600

aggcggaagc cgtccgtgcc atgcccagaa cccaggacca catctggtca gcaaggtata      660

tggacttcca ctgaatccct ctcatcctcc aacagtgatg acaacaagca gtgccccaac      720

ttcctcatag ccagaagtca agttacatca actccaatct caaagccacc tccccctctg      780

gagacctcac tcccttttct taccatccca gaaaatcgac agctgccacc tccctcacca      840

caactcccaa agcataacct tcatgtcacc aagacactga tggagacccg gagaagactg      900

gaacaggaga gagccaccat gcagatgaca ccgggtgagt tcagaaggcc caggctggcc      960

agttttggag gcatgggcac cacaagctcc ctcccttctt ttgtgggttc tggaaaccac     1020

aatcctgcca agcaccagct tcagaatgga taccaaggta atggggatta tggtagctat     1080

gccccagctg ctcccaccac ttcctccatg gggagctcca tccgccacag ccccctgagc     1140

tcagggatct ccaccccagt gaccaacgtg agccccatgc acctgcagca catccgcgag     1200

cagatggcca ttgctctgaa acgcctgaag gagctggagg agcaggtgcg aaccatccct     1260

gtgctccagg taaagatctc tgtcttgcaa gaagagaaaa ggcagttggt ctcacagctg     1320

aaaaaccaaa gggctgcatc ccagatcaat gtctgtggtg tgaggaagcg gtcctatagt     1380

gcggggaacg cctcccagct ggaacagctc tcccgggccc gaagaagtgg cggggaatta     1440

tacattgact atgaggagga agaaatggag accgtagaac agagcacgca gaggataaag     1500

gagttccggc aacttacagc agacatgcaa gccctggagc agaagatcca ggacagcagc     1560

tgtgaggcct cctcagagct cagggagaat ggagagtgcc ggtctgtggc tgtgggtgcc     1620

gaggagaaca tgaacgacat cgtcgtgtac cacagaggct ccaggtcctg taaggatgca     1680

gctgtaggga cacttgttga gatgagaaat tgtggggtca gcgtgacaga ggccatgctt     1740

ggagtgatga ctgaagctga caaagaaatt gagctgcaac agcagaccat agaatccttg     1800

aaggaaaaga tctatcgcct agaagtacag cttagagaaa ccacccatga ccgggagatg     1860

actaaactga aacaagagct gcaggctgct ggatcgagga aaaaggttga caaagccacg     1920

atggcccagc cgcttgtttt cagtaaggtg gtggaggcag tggtgcagac cagagaccaa     1980

atggtcggca gtcacatgga cctggtggac acgtgtgttg ggacctccgt ggaaacaaac     2040

agtgtaggca tctcctgcca gcctgaatgt aagaataaag tcgtagggcc tgagctgcct     2100

atgaattggt ggattgttaa ggagagggtg gaaatgcatg accgatgtgc tgggaggtct     2160

gtggaaatgt gtgacaagag tgtgagtgtg gaagtcagcg tctgcgaaac aggcagcaac     2220

acagaggagt ctgtgaacga cctcacactc ctcaagacaa acttgaatct caaagaagtg     2280

cggtctatcg gttgtggaga ttgttctgtt gacgtgaccg tctgctctcc aaaggagtgc     2340

gcctcccggg gcgtgaacac tgaggctgtt agccaggtgg aagctgccgt catggcagtg     2400

cctcgtactg cagaccagga cactagcaca gatttggaac aggtgcacca gttcaccaac     2460

accgagacgg ccaccctcat agagtcctgc accaacactt gtctaagcac tttggacaag     2520

cagaccagca cccagactgt ggagacgcgg acagtagctg taggagaagg ccgtgtcaag     2580

gacatcaact cctccaccaa gacgcggtcc attggtgttg gaacgttgct ttctggccat     2640

tctgggtttg acaggccatc agctgtgaag accaaagagt caggtgtggg gcagataaat     2700

attaacgaca actatctggt tggtctcaaa atgaggacta tagcttgtgg gccaccacag     2760

ttgactgtgg ggctgacagc cagcagaagg agcgtggggg ttggggatga ccctgtaggg     2820

gaatctctgg agaaccccca gcctcaagct ccacttggaa tgatgactgg cctggatcac     2880

tacattgagc gtatccagaa gctgctggca gaacagcaga cactgctggc tgagaactac     2940

agtgaactgg cagaagcttt cggggaacct cactcacaga tgggctccct caactctcag     3000

ctcatcagca ccctgtcgtc tatcaactct gtcatgaaat ctgcaagcac tgaagagctg     3060

aggaaccctg acttccagaa aaccagtctg ggtaaaatca caggcaatta tttgggatat     3120

acctgtaagt gtgggggcct tcagtcagga agtcccttaa gctcccagac atcccagcct     3180

gagcaagaag tggggacctc agaaggaaag ccaatcagca gcctggatgc cttccccact     3240

caggaaggta cgctgtctcc agtgaacctg acagacgacc agatcgccgc tggcctctat     3300

gcatgtacaa acaatgaaag tacactgaag tccatcatga agaagaaaga tggtaacaaa     3360

gattcaaatg gcgcaaaaaa gaatcttcag tttgttggca ttaatggagg gtatgaaaca     3420

acttcaagtg atgattccag ctcagatgaa agctcttctt ccgagtcaga tgacgagtgt     3480

gatgtcattg agtatcctct tgaagaagag gaggaggagg aggatgaaga cactcgggga     3540

atggcagaag ggcaccatgc agttaatatt gaaggtttga agtctgccag ggtggaagat     3600

gaaatgcagg ttcaagaatg tgaacctgag aaggtggaaa tcagagagag gtatgaatta     3660

agtgaaaaga tgttgtctgc atgcaactta ctgaaaaata ctataaatga ccccaaagct     3720

ttgaccagca aagatatgag gttctgtctg aacaccctcc agcacgagtg gttccgcgtg     3780

tccagtcaga agtcagccat tccagccatg gtgggggact acatagctgc ttttgaggcc     3840

atttccccag atgtcctccg ctatgtcatc aacttggcag acggcaacgg caacacagcc     3900

ctccattaca gcgtgtccca ctccaacttc gagattgtga agctgctgtt agatgccgat     3960

gtgtgtaatg tggatcacca gaacaaggca ggctacaccc ccatcatgtt ggcggccctc     4020

gccgctgtgg aagcagagaa ggacatgcgg attgtggaag aactcttcgg ctgtggggat     4080

gtgaatgcca aagctagtca ggcgggacag acggccctca tgctggcggt cagtcacgga     4140

cggatagaca tggtgaaggg ccttctggcc tgtggggctg atgtcaacat ccaggatgac     4200

gagggctcca cggccctcat gtgtgccagc gagcacgggc acgtggagat tgtcaagctg     4260

ctgctggccc agcccggctg caacggtcac ctagaggaca acgatggcag cactgcgctc     4320

tcaatcgccc tggaagcagg acacaaggac atcgctgttc ttctgtatgc ccatgtcaac     4380

tttgcaaaag cccagtctcc gggcacccct aggcttggaa ggaagacgtc tcctggcccc     4440

acccaccgag gttcatttga ttgattgtat gcaaatagcc ctttatttac atgccactat     4500

taagctgcta attgttcctg ttggggtgac agatactgaa tgtatacgta ttgtgcctga     4560

gctcaccagc aaacagaagc atcaagccca ggggtaaagg ctgaagcttt cacagtgcag     4620

agactgctag cctgggcaca cacacctcct ttctggccgt cttctgtgta gggcacactt     4680

taacccagtc tctgttgctg ttgagtctct gctccgtttt gtacagtcac agggaattct     4740

gatctgaagg ggcaccttct gttcactccc acaaagtggt gtctggttct cactgagacg     4800

ttttaagatt tttccacaaa tatttatatg tactaaatgt ggaaccatta gaaagttctt     4860

ccaaaatctc attccagcat agttttggat ttttcttttg tcttatttta aaataaggaa     4920

gtcgagatga ctttgatcat tggtaacttg ggcctgggcc agacaaagta taaaacttac     4980

aaaagaatat tctcatttgg tcttaactag gtagatgtaa tatatgactt tttataaaaa     5040

gggtatctat atgaacttga cacagtattt tcagcttttg tattccatac taaagccatg     5100

aagaactaca cgtaacatca tcatttgtat taattgcaca actccaatgc taaaggttgg     5160

attgtgttag aggaatcggc tctgtatttg cctctagaga aacacagtgt tctctttgta     5220

tttatggatt cctttttacc gtgtcacatt tactttggtc ctctatgtat ttaaatgttt     5280

gaagtgcctt agactcttgc catattttca aaataaaatt ccattaagct cttttaaaaa     5340

aaaaaaaaaa aa                                                         5352


<210>  348
<211>  5090
<212>  DNA
<213>  homo sapiens

<400>  348
gagctccggg tccgcggcgg agcgagcgag cggccggcag gttgggagga gcggccgaag       60

gttgaatgcc tttgagaact tgatgcataa aatttgcatg actcctcact cctttctgga      120

tctctcattg gactcaagcc agcatggctc acaccacaaa ggttaacggc agtgcctcag      180

gaaaagcagg tgatattctc agtggagacc aggacaagga acagaaagac ccttactttg      240

tggagacccc ctatggttat caactagact tagatttcct caaatatgtg gatgacatac      300

agaagggaaa taccatcaaa agactgaaca tccagaagag gcggaagccg tccgtgccat      360

gcccagaacc caggaccaca tctggtcagc aaggtatatg gacttccact gaatccctct      420

catcctccaa cagtgatgac aacaagcagt gccccaactt cctcatagcc agaagtcaag      480

ttacatcaac tccaatctca aagccacctc cccctctgga gacctcactc ccttttctta      540

ccatcccaga aaatcgacag ctgccacctc cctcaccaca actcccaaag cataaccttc      600

atgtcaccaa gacactgatg gagacccgga gaagactgga acaggagaga gccaccatgc      660

agatgacacc gggtgagttc agaaggccca ggctggccag ttttggaggc atgggcacca      720

caagctccct cccttctttt gtgggttctg gaaaccacaa tcctgccaag caccagcttc      780

agaatggata ccaaggtaat ggggattatg gtagctatgc cccagctgct cccaccactt      840

cctccatggg gagctccatc cgccacagcc ccctgagctc agggatctcc accccagtga      900

ccaacgtgag ccccatgcac ctgcagcaca tccgcgagca gatggccatt gctctgaaac      960

gcctgaagga gctggaggag caggtgcgaa ccatccctgt gctccaggta aagatctctg     1020

tcttgcaaga agagaaaagg cagttggtct cacagctgaa aaaccaaagg gctgcatccc     1080

agatcaatgt ctgtggtgtg aggaagcggt cctatagtgc ggggaacgcc tcccagctgg     1140

aacagctctc ccgggcccga agaagtggcg gggaattata cattgactat gaggaggaag     1200

aaatggagac cgtagaacag agcacgcaga ggataaagga gttccggcaa cttacagcag     1260

acatgcaagc cctggagcag aagatccagg acagcagctg tgaggcctcc tcagagctca     1320

gggagaatgg agagtgccgg tctgtggctg tgggtgccga ggagaacatg aacgacatcg     1380

tcgtgtacca cagaggctcc aggtcctgta aggatgcagc tgtagggaca cttgttgaga     1440

tgagaaattg tggggtcagc gtgacagagg ccatgcttgg agtgatgact gaagctgaca     1500

aagaaattga gctgcaacag cagaccatag aatccttgaa ggaaaagatc tatcgcctag     1560

aagtacagct tagagaaacc acccatgacc gggagatgac taaactgaaa caagagctgc     1620

aggctgctgg atcgaggaaa aaggttgaca aagccacgat ggcccagccg cttgttttca     1680

gtaaggtggt ggaggcagtg gtgcagacca gagaccaaat ggtcggcagt cacatggacc     1740

tggtggacac gtgtgttggg acctccgtgg aaacaaacag tgtaggcatc tcctgccagc     1800

ctgaatgtaa gaataaagtc gtagggcctg agctgcctat gaattggtgg attgttaagg     1860

agagggtgga aatgcatgac cgatgtgctg ggaggtctgt ggaaatgtgt gacaagagtg     1920

tgagtgtgga agtcagcgtc tgcgaaacag gcagcaacac agaggagtct gtgaacgacc     1980

tcacactcct caagacaaac ttgaatctca aagaagtgcg gtctatcggt tgtggagatt     2040

gttctgttga cgtgaccgtc tgctctccaa aggagtgcgc ctcccggggc gtgaacactg     2100

aggctgttag ccaggtggaa gctgccgtca tggcagtgcc tcgtactgca gaccaggaca     2160

ctagcacaga tttggaacag gtgcaccagt tcaccaacac cgagacggcc accctcatag     2220

agtcctgcac caacacttgt ctaagcactt tggacaagca gaccagcacc cagactgtgg     2280

agacgcggac agtagctgta ggagaaggcc gtgtcaagga catcaactcc tccaccaaga     2340

cgcggtccat tggtgttgga acgttgcttt ctggccattc tgggtttgac aggccatcag     2400

ctgtgaagac caaagagtca ggtgtggggc agataaatat taacgacaac tatctggttg     2460

gtctcaaaat gaggactata gcttgtgggc caccacagtt gactgtgggg ctgacagcca     2520

gcagaaggag cgtgggggtt ggggatgacc ctgtagggga atctctggag aacccccagc     2580

ctcaagctcc acttggaatg atgactggcc tggatcacta cattgagcgt atccagaagc     2640

tgctggcaga acagcagaca ctgctggctg agaactacag tgaactggca gaagctttcg     2700

gggaacctca ctcacagatg ggctccctca actctcagct catcagcacc ctgtcgtcta     2760

tcaactctgt catgaaatct gcaagcactg aagagctgag gaaccctgac ttccagaaaa     2820

ccagtctggg taaaatcaca ggcaattatt tgggatatac ctgtaagtgt gggggccttc     2880

agtcaggaag tcccttaagc tcccagacat cccagcctga gcaagaagtg gggacctcag     2940

aaggaaagcc aatcagcagc ctggatgcct tccccactca ggaaggtacg ctgtctccag     3000

tgaacctgac agacgaccag atcgccgctg gcctctatgc atgtacaaac aatgaaagta     3060

cactgaagtc catcatgaag aagaaagatg gtaacaaaga ttcaaatggc gcaaaaaaga     3120

atcttcagtt tgttggcatt aatggagggt atgaaacaac ttcaagtgat gattccagct     3180

cagatgaaag ctcttcttcc gagtcagatg acgagtgtga tgtcattgag tatcctcttg     3240

aagaagagga ggaggaggag gatgaagaca ctcggggaat ggcagaaggg caccatgcag     3300

ttaatattga aggtttgaag tctgccaggg tggaagatga aatgcaggtt caagaatgtg     3360

aacctgagaa ggtggaaatc agagagaggt atgaattaag tgaaaagatg ttgtctgcat     3420

gcaacttact gaaaaatact ataaatgacc ccaaagcttt gaccagcaaa gatatgaggt     3480

tctgtctgaa caccctccag cacgagtggt tccgcgtgtc cagtcagaag tcagccattc     3540

cagccatggt gggggactac atagctgctt ttgaggccat ttccccagat gtcctccgct     3600

atgtcatcaa cttggcagac ggcaacggca acacagccct ccattacagc gtgtcccact     3660

ccaacttcga gattgtgaag ctgctgttag atgccgatgt gtgtaatgtg gatcaccaga     3720

acaaggcagg ctacaccccc atcatgttgg cggccctcgc cgctgtggaa gcagagaagg     3780

acatgcggat tgtggaagaa ctcttcggct gtggggatgt gaatgccaaa gctagtcagg     3840

cgggacagac ggccctcatg ctggcggtca gtcacggacg gatagacatg gtgaagggcc     3900

ttctggcctg tggggctgat gtcaacatcc aggatgacga gggctccacg gccctcatgt     3960

gtgccagcga gcacgggcac gtggagattg tcaagctgct gctggcccag cccggctgca     4020

acggtcacct agaggacaac gatggcagca ctgcgctctc aatcgccctg gaagcaggac     4080

acaaggacat cgctgttctt ctgtatgccc atgtcaactt tgcaaaagcc cagtctccgg     4140

gcacccctag gcttggaagg aagacgtctc ctggccccac ccaccgaggt tcatttgatt     4200

gattgtatgc aaatagccct ttatttacat gccactatta agctgctaat tgttcctgtt     4260

ggggtgacag atactgaatg tatacgtatt gtgcctgagc tcaccagcaa acagaagcat     4320

caagcccagg ggtaaaggct gaagctttca cagtgcagag actgctagcc tgggcacaca     4380

cacctccttt ctggccgtct tctgtgtagg gcacacttta acccagtctc tgttgctgtt     4440

gagtctctgc tccgttttgt acagtcacag ggaattctga tctgaagggg caccttctgt     4500

tcactcccac aaagtggtgt ctggttctca ctgagacgtt ttaagatttt tccacaaata     4560

tttatatgta ctaaatgtgg aaccattaga aagttcttcc aaaatctcat tccagcatag     4620

ttttggattt ttcttttgtc ttattttaaa ataaggaagt cgagatgact ttgatcattg     4680

gtaacttggg cctgggccag acaaagtata aaacttacaa aagaatattc tcatttggtc     4740

ttaactaggt agatgtaata tatgactttt tataaaaagg gtatctatat gaacttgaca     4800

cagtattttc agcttttgta ttccatacta aagccatgaa gaactacacg taacatcatc     4860

atttgtatta attgcacaac tccaatgcta aaggttggat tgtgttagag gaatcggctc     4920

tgtatttgcc tctagagaaa cacagtgttc tctttgtatt tatggattcc tttttaccgt     4980

gtcacattta ctttggtcct ctatgtattt aaatgtttga agtgccttag actcttgcca     5040

tattttcaaa ataaaattcc attaagctct tttaaaaaaa aaaaaaaaaa                5090


<210>  349
<211>  4728
<212>  DNA
<213>  homo sapiens

<400>  349
gcggagacgg ggaaggggtc gccgtggctg ccggtcctcg agttgggggc tgccgcggac       60

actgctaggc agacggcgag taccgagcgc gggtggccgc ggtgtccgtg ggccacgctc      120

agctgcggtc agaggcgaca tgagtgccgc ggggctgctg gccccggccc cggcccaggc      180

tggagcgccg ccggcccccg agtactaccc cgaggaggat gaagagctgg agagcgccga      240

ggacgacgag cgcagctgtc ggggccgcga gtcggacgaa gacactgagg atgctagtga      300

aactgacctg gcaaagcatg atgaagaaga ctatgtagaa atgaaggaac agatgtatca      360

ggacaaactg gcttctctca agaggcagtt gcaacaactg caagaaggta cattacagga      420

atatcagaag agaatgaaaa aactagatca gcagtacaaa gagaggatac ggaatgcaga      480

actcttcctc cagctggaaa ctgaacaagt ggaacgaaat tacattaaag aaaagaaggc      540

agcagtgaaa gaatttgaag acaagaaggt tgagctgaaa gagaacctga ttgctgagct      600

agaagaaaag aagaaaatga ttgaaaatga aaagctgaca atggaactga ctggagattc      660

tatggaggtg aaacctatca tgaccagaaa gttgcggagg cgaccaaatg atcccgtccc      720

catcccagac aagaggagga aacctgctcc agcccagcta aactatttgt taacagatga      780

acagatcatg gaggatctga gaacattaaa taagcttaag tcacccaaga gaccagcatc      840

tccatcctct cctgagcact tgcctgcaac acccgcggaa tctccagccc agaggttcga      900

agctcggata gaagatggca aactgtacta tgacaaaaga tggtaccaca agagccaggc      960

catctatctg gagtcaaagg acaaccagaa actgagctgc gtgatcagtt ctgtaggagc     1020

caatgagatc tgggtgagga agacaagtga cagcaccaag atgaggatct acctgggcca     1080

gcttcagcgc gggctcttcg tgatccgccg gcgctcagct gcttgacttt ctacagtgct     1140

cttctcttga ccctttttct ggagtgggtt ttatttttgt tttgtttcgt tttctcctta     1200

atagaaaaat gttaacttac tgggaatagc tactcagcct tggaaatgga gagcactgca     1260

gtgaattctt tagggcactt ttgtggccgg atgcttccaa ctttgtcagt cttttctgcc     1320

tcaacttctt ccagacatca gtcaccatga gactgtttta ctttcaggcg tattgggggg     1380

tttgatttac tttcctttta tttctttatt ttttgcttat acttgttttt gaaaacctcc     1440

tctgagtttg aagggacagc tatttttatt gattatcttt aagtctctct accatggaga     1500

agagcaggaa gggatacact ctccagtgca ttttcatgtt ttgaatctga ttagtggatc     1560

acgtagctac tttccctgtc gcgtccaatt cactatttgc ccagaagctt ggggcagagg     1620

tcctagcagg agatgatgaa ttctcgtggc tctcggcctt ctcagagaaa taaatgcttt     1680

gtgtaacatc tgtgcacacc atccattccg ctcgctgagc gatggaaaag cttgcctgga     1740

agactatgtg cactgaagta aatggggttg ggggagggga catttcatat ttataatgtg     1800

ctgaaggtac catattttaa atgttattta atgcaggtga tttattcaaa catttgttct     1860

agcttaagct ggaataagca gtggtcattt cagaagtttt catttgtaat tccttcctct     1920

cccttgttcc caagtaggta gtagtaagta tgtgccacag gctgattatc tgggtaatct     1980

tttacgggtg ggaggtgaga ttgatagtgc aataatcagt gatctataga ccctcatgca     2040

cgattcaagt ttcactcttg tggctgatgc cattattgca cattggccat tccaaacctg     2100

tggagaactt tgttgtcagg ccctgagcgc tcacagcttc atttggccca ggttgaagac     2160

aaggaaagct ctgctgtggc tgcctctgga ctgacaccct ccctaatgag tcctgatgaa     2220

acagcctttc ctacatcctt ccctcactcc catgattgga gaaatgattc attgggtgat     2280

gagtgttggg gttttctata ctcatgttgc catcttgaga tgttcaaaaa atttggggtt     2340

agagcaactg ttagcgtctc tatgagcaat cagtagaact tacacatcct aggaaatctt     2400

tctttgtaag taattctttt ggtctcaagt gattctcttc atgttgtctc ttgatgtaca     2460

tacccccaag caagttgggg ggactgtgat gacaattaaa tcaccttctc tgaagttctg     2520

gctctgcaga gaccaaacct tactgacttg tacagacttg tacaagtaaa gacttataca     2580

gatagatttt tgttttaact tacaatccgt tttttcctct tttttttttt tttttctggt     2640

gttggagtct tatttagaaa acaggataaa tgacgctgtt atcaaaagtt gcctggggtt     2700

ctgtatttct tctctgccct ccaatccccg actgctatga tgtttactac agtgaaccca     2760

gcccatggta aacacaggct tcacctgttc ttgtttgtta gccttgactg tgaggcagga     2820

cttccctcgc ttgaactgtt acacatacga tgtgtgtgtc acatcacata ttgtgcagct     2880

gttggttttc atgtagtgcc ctgcgatgga aattagatat atttcatgta tttttccatt     2940

gaaggtggag tttttcaatg atcatgtgtt ttgtcctcct aaacagtata ccaaagtttg     3000

tttttatagt tgaggattgt attgataacc actggggttc cgcattgaag caggaacaaa     3060

ttgcctcttt ttctggcctt ctctgtggga cctctgcttt tgtgaagcaa ctatttattt     3120

gaagaccagg gtatgggcac ttttgccttc tctcctctct gacttttgag ggtattgagg     3180

gcgcccttag tcatagtctc gactccgcca ttgccttctc ctcggcgtcc tcacaactct     3240

taattgggcc tagtgaaaat gggggcaggt gagaagtcca ttttgagaat cagcatagta     3300

aattacattt ctaatcccag aggacttaat attttctttt gtcaccccag aggtgaaaaa     3360

tcagcagttg aagcctgaca ggcctcagtg gtgaccagga acagaagcag ccttcctgtt     3420

agtagatggg ggtacttctg tggtgggcag aagccttact aaaggggaag acagactttg     3480

aagtttctag acgagaagga ggctagcttc tagcctgggt ggccattatt ccaaaaggtc     3540

attgtttctc actagacccc agggcaccag atgaatttcc aagtttaaac tctttcctgc     3600

aggtgattac tttgaaaaag gttggtccag accattttga tcaagaacct gtatatgtgt     3660

tgtgttagag gcatctgcct caagtctatg tacagtgttt gctgcgggtg tgttccaata     3720

ttcattttac ctctgcttgg gggttttgtg tgttcccctc cccccatgcc ctgcctaccc     3780

ccttttccct gaaccacgtc cttttgaata atttccagat ggatttctgt agccatacca     3840

aagccagggt gttttcattc atgcggatac tagtatttat agatgtctga ctacctaact     3900

taatttttgt ttttgaactt ctaattgggg ccagtgtaag gtcgatccca gaggctgatc     3960

tgcaaatcaa gctacatgta tttgtgtata agaccctgtg ttcaggactg ggtgactttt     4020

ctaagaaata tggggtttag aatggggttg actgtatttt ttaacctaat tctggagaga     4080

agattgtatt ttttacagtt ttttgggttt ggcttccttc tcacatttct ttagctttga     4140

atttttacta aataaatttc ctcctgatta attttttttt tctcatctgg gaatttgaaa     4200

tctcggtgct tactgttaca ccaatttgtc caaagagttg aaatcacttt aatgccagaa     4260

catggtaaat ttgcagccat ttcaagcagg tgatggtctt tttttataac atcgttaacg     4320

ggtaccatta aatattctga gaggtgaatg taaaatataa aaggtatagg tttttttttt     4380

tttttaaaga aaacaataaa ctttcaaaga gaaaaccagc atgaagtctg tattgtatcc     4440

attgacttga taagtgatag aaatttattt taggtttttg atccattgct tatggggaaa     4500

ggaagttagg gcagaggaag ggatattcta gacatttaat tcttagtgaa gactaagata     4560

cagaatgatg tcaggctaat actcagtttt gtaaagagca atctggggtg ttgaccctta     4620

aatgtttgtg cactcttctt gttgcagata aaagtcatta aaaatcaagt gaatagaatg     4680

gatcttgggt ggaaaaacaa tcttgaaata aacttgtgat tgaggata                  4728


<210>  350
<211>  4728
<212>  DNA
<213>  homo sapiens

<400>  350
gcggagacgg ggaaggggtc gccgtggctg ccggtcctcg agttgggggc tgccgcggac       60

actgctaggc agacggcgag taccgagcgc gggtggccgc ggtgtccgtg ggccacgctc      120

agctgcggtc agaggcgaca tgagtgccgc ggggctgctg gccccggccc cggcccaggc      180

tggagcgccg ccggcccccg agtactaccc cgaggaggat gaagagctgg agagcgccga      240

ggacgacgag cgcagctgtc ggggccgcga gtcggacgaa gacactgagg atgctagtga      300

aactgacctg gcaaagcatg atgaagaaga ctatgtagaa atgaaggaac agatgtatca      360

ggacaaactg gcttctctca agaggcagtt gcaacaactg caagaaggta cattacagga      420

atatcagaag agaatgaaaa aactagatca gcagtacaaa gagaggatac ggaatgcaga      480

actcttcctc cagctggaaa ctgaacaagt ggaacgaaat tacattaaag aaaagaaggc      540

agcagtgaaa gaatttgaag acaagaaggt tgagctgaaa gagaacctga ttgctgagct      600

agaagaaaag aagaaaatga ttgaaaatga aaagctgaca atggaactga ctggagattc      660

tatggaggtg aaacctatca tgaccagaaa gttgcggagg cgaccaaatg atcccgtccc      720

catcccagac aagaggagga aacctgctcc agcccagcta aactatttgt taacagatga      780

acagatcatg gaggatctga gaacattaaa taagcttaag tcacccaaga gaccagcatc      840

tccatcctct cctgagcact tgcctgcaac acccgcggaa tctccagccc agaggttcga      900

agctcggata gaagatggca aactgtacta tgacaaaaga tggtaccaca agagccaggc      960

catctatctg gagtcaaagg acaaccagaa actgagctgc gtgatcagtt ctgtaggagc     1020

caatgagatc tgggtgagga agacaagtga cagcaccaag atgaggatct acctgggcca     1080

gcttcagcgc gggctcttcg tgatccgccg gcgctcagct gcttgacttt ctacagtgct     1140

cttctcttga ccctttttct ggagtgggtt ttatttttgt tttgtttcgt tttctcctta     1200

atagaaaaat gttaacttac tgggaatagc tactcagcct tggaaatgga gagcactgca     1260

gtgaattctt tagggcactt ttgtggccgg atgcttccaa ctttgtcagt cttttctgcc     1320

tcaacttctt ccagacatca gtcaccatga gactgtttta ctttcaggcg tattgggggg     1380

tttgatttac tttcctttta tttctttatt ttttgcttat acttgttttt gaaaacctcc     1440

tctgagtttg aagggacagc tatttttatt gattatcttt aagtctctct accatggaga     1500

agagcaggaa gggatacact ctccagtgca ttttcatgtt ttgaatctga ttagtggatc     1560

acgtagctac tttccctgtc gcgtccaatt cactatttgc ccagaagctt ggggcagagg     1620

tcctagcagg agatgatgaa ttctcgtggc tctcggcctt ctcagagaaa taaatgcttt     1680

gtgtaacatc tgtgcacacc atccattccg ctcgctgagc gatggaaaag cttgcctgga     1740

agactatgtg cactgaagta aatggggttg ggggagggga catttcatat ttataatgtg     1800

ctgaaggtac catattttaa atgttattta atgcaggtga tttattcaaa catttgttct     1860

agcttaagct ggaataagca gtggtcattt cagaagtttt catttgtaat tccttcctct     1920

cccttgttcc caagtaggta gtagtaagta tgtgccacag gctgattatc tgggtaatct     1980

tttacgggtg ggaggtgaga ttgatagtgc aataatcagt gatctataga ccctcatgca     2040

cgattcaagt ttcactcttg tggctgatgc cattattgca cattggccat tccaaacctg     2100

tggagaactt tgttgtcagg ccctgagcgc tcacagcttc atttggccca ggttgaagac     2160

aaggaaagct ctgctgtggc tgcctctgga ctgacaccct ccctaatgag tcctgatgaa     2220

acagcctttc ctacatcctt ccctcactcc catgattgga gaaatgattc attgggtgat     2280

gagtgttggg gttttctata ctcatgttgc catcttgaga tgttcaaaaa atttggggtt     2340

agagcaactg ttagcgtctc tatgagcaat cagtagaact tacacatcct aggaaatctt     2400

tctttgtaag taattctttt ggtctcaagt gattctcttc atgttgtctc ttgatgtaca     2460

tacccccaag caagttgggg ggactgtgat gacaattaaa tcaccttctc tgaagttctg     2520

gctctgcaga gaccaaacct tactgacttg tacagacttg tacaagtaaa gacttataca     2580

gatagatttt tgttttaact tacaatccgt tttttcctct tttttttttt tttttctggt     2640

gttggagtct tatttagaaa acaggataaa tgacgctgtt atcaaaagtt gcctggggtt     2700

ctgtatttct tctctgccct ccaatccccg actgctatga tgtttactac agtgaaccca     2760

gcccatggta aacacaggct tcacctgttc ttgtttgtta gccttgactg tgaggcagga     2820

cttccctcgc ttgaactgtt acacatacga tgtgtgtgtc acatcacata ttgtgcagct     2880

gttggttttc atgtagtgcc ctgcgatgga aattagatat atttcatgta tttttccatt     2940

gaaggtggag tttttcaatg atcatgtgtt ttgtcctcct aaacagtata ccaaagtttg     3000

tttttatagt tgaggattgt attgataacc actggggttc cgcattgaag caggaacaaa     3060

ttgcctcttt ttctggcctt ctctgtggga cctctgcttt tgtgaagcaa ctatttattt     3120

gaagaccagg gtatgggcac ttttgccttc tctcctctct gacttttgag ggtattgagg     3180

gcgcccttag tcatagtctc gactccgcca ttgccttctc ctcggcgtcc tcacaactct     3240

taattgggcc tagtgaaaat gggggcaggt gagaagtcca ttttgagaat cagcatagta     3300

aattacattt ctaatcccag aggacttaat attttctttt gtcaccccag aggtgaaaaa     3360

tcagcagttg aagcctgaca ggcctcagtg gtgaccagga acagaagcag ccttcctgtt     3420

agtagatggg ggtacttctg tggtgggcag aagccttact aaaggggaag acagactttg     3480

aagtttctag acgagaagga ggctagcttc tagcctgggt ggccattatt ccaaaaggtc     3540

attgtttctc actagacccc agggcaccag atgaatttcc aagtttaaac tctttcctgc     3600

aggtgattac tttgaaaaag gttggtccag accattttga tcaagaacct gtatatgtgt     3660

tgtgttagag gcatctgcct caagtctatg tacagtgttt gctgcgggtg tgttccaata     3720

ttcattttac ctctgcttgg gggttttgtg tgttcccctc cccccatgcc ctgcctaccc     3780

ccttttccct gaaccacgtc cttttgaata atttccagat ggatttctgt agccatacca     3840

aagccagggt gttttcattc atgcggatac tagtatttat agatgtctga ctacctaact     3900

taatttttgt ttttgaactt ctaattgggg ccagtgtaag gtcgatccca gaggctgatc     3960

tgcaaatcaa gctacatgta tttgtgtata agaccctgtg ttcaggactg ggtgactttt     4020

ctaagaaata tggggtttag aatggggttg actgtatttt ttaacctaat tctggagaga     4080

agattgtatt ttttacagtt ttttgggttt ggcttccttc tcacatttct ttagctttga     4140

atttttacta aataaatttc ctcctgatta attttttttt tctcatctgg gaatttgaaa     4200

tctcggtgct tactgttaca ccaatttgtc caaagagttg aaatcacttt aatgccagaa     4260

catggtaaat ttgcagccat ttcaagcagg tgatggtctt tttttataac atcgttaacg     4320

ggtaccatta aatattctga gaggtgaatg taaaatataa aaggtatagg tttttttttt     4380

tttttaaaga aaacaataaa ctttcaaaga gaaaaccagc atgaagtctg tattgtatcc     4440

attgacttga taagtgatag aaatttattt taggtttttg atccattgct tatggggaaa     4500

ggaagttagg gcagaggaag ggatattcta gacatttaat tcttagtgaa gactaagata     4560

cagaatgatg tcaggctaat actcagtttt gtaaagagca atctggggtg ttgaccctta     4620

aatgtttgtg cactcttctt gttgcagata aaagtcatta aaaatcaagt gaatagaatg     4680

gatcttgggt ggaaaaacaa tcttgaaata aacttgtgat tgaggata                  4728


<210>  351
<211>  4615
<212>  DNA
<213>  homo sapiens

<400>  351
acacttcact caaatggctg gctgcagctg gtgctagtta tggtctggga tctcagatga       60

ggctgctaag ccgaatgtgt tgttactcct ttacatcgtc tctccacatg gcttgaactt      120

ctcacagcat gcctgctgga ttcgaagaga tggcattcaa gtgcttaaaa atcaagaaga      180

ccctcaccag gtgccagcgt ctagacattg gattttccag cctccagaac ttacttctag      240

tctagttgga gaaacaacct agaaaatgca ccaacaaatg gggcacaata actactctga      300

gagagagtgg cacacagtgg acgcaaagaa gaggttcctg atgcagctgg gaagagtcta      360

catgggcctc tagcaggaga agatactggt cttgagtttg gagactaagt aagcatctcc      420

agtgtcgaat aggtacctgg gtcaactcca cacacttctc actcttcact ggacctctgg      480

tacaagattg agaggattcc tattacttac aaacagacta gttcatctgg ctctccatga      540

atgtcctgct tttctggaaa accttcttgc tgtataacca agggccagag tatcactacc      600

tccaccagat gttggggcta ggattgtgtc taagcagagc ctcagcatct gttcttaacc      660

tcaactgcag ccttatcctt ttacccatgt gccgaacact cttggcttac ctccgaggat      720

cacagaaggt tccaagcagg agaaccagga gattgttgga taaaagcaga acattccata      780

ttacctgtgg tgttactatc tgtattttct caggcgtgca tgtggctgcc catctggtga      840

atgccctcaa cttctcagtg aattacagtg aagactttgt tgaactgaat gcagcaagat      900

accgagatga ggatcctaga aaacttctct tcacaactgt tcctggcctg acaggggtct      960

gcatggtggt ggtgctattc ctcatgatca cagcctctac atatgcaata agagtttcta     1020

actatgatat cttctggtat actcataacc tcttctttgt cttctacatg ctgctgacgt     1080

tgcatgtttc aggagggctg ctgaagtatc aaactaattt agatacccac cctcccggct     1140

gcatcagtct taaccgaacc agctctcaga atatttcctt accagagtat ttctcagaac     1200

attttcatga acctttccct gaaggatttt caaaaccggc agagtttacc cagcacaaat     1260

ttgtgaagat ttgtatggaa gagcccagat tccaagctaa ttttccacag acttggcttt     1320

ggatttctgg acctttgtgc ctgtactgtg ccgaaagact ttacaggtat atccggagca     1380

ataagccagt caccatcatt tcggtcataa gtcatccctc agatgtcatg gaaatccgaa     1440

tggtcaaaga aaattttaaa gcaagacctg gtcagtatat tactctacat tgtcccagtg     1500

tatctgcatt agaaaatcat ccatttaccc tcacaatgtg tccaactgaa accaaagcaa     1560

catttggggt tcatcttaaa atagtaggag actggacaga acgatttcga gatttactac     1620

tgcctccatc tagtcaagac tccgaaattc tgcccttcat tcaatctaga aattatccca     1680

agctgtatat tgatggtcct tttggaagtc catttgagga atcactgaac tatgaggtca     1740

gcctctgcgt ggctggaggc attggagtaa ctccatttgc atcaatactc aacaccctgt     1800

tggatgactg gaaaccatac aagcttagaa gactatactt tatttgggta tgcagagata     1860

tccagtcctt ccgttggttt gcagatttac tctgtatgtt gcataacaag ttttggcaag     1920

agaacagacc tgactatgtc aacatccagc tgtacctcag tcaaacagat gggatacaga     1980

agataattgg agaaaaatat catgcactga attcaagact gtttatagga cgtcctcggt     2040

ggaaactttt gtttgatgaa atagcaaaat ataacagagg aaaaacagtt ggtgttttct     2100

gttgtggacc caattcacta tccaagactc ttcataaact gagtaaccag aacaactcat     2160

atgggacaag atttgaatac aataaagagt ctttcagctg aaaacttttg ccatgaagca     2220

ggactctaaa gaaggaatga gtgcaatttc taagactttg aaactcagcg gaatcaatca     2280

gctgtgttat gccaaagaat agtaaggttt tcttatttat gattatttaa aatggaaatg     2340

tgagaatgtg gcaagatgac cgtcacatta catgtttaat ctggaaacca aagagaccct     2400

gaagaatatt tgatgtgatg attcactttt cagttctcaa attaaaagaa aactgttaga     2460

tgcacactgt tgattttcat ggtggattca agaactccct agtgaggagc tgaacttgct     2520

caatctaagg ctgattgtcg tgttcctctt taaattgttt ttggttgaac aaatgcaaga     2580

ttgaacaaaa ttaaaaattc attgaagctg aaattccatt ttctgtgttg tgtataaaca     2640

gagtagcttt aatttgcaag cactccaggc aaatatatta gatgtttgaa aacacagcac     2700

aagactctgt attgatacgg gtactttgtg tcaatatcta atcgtctcca ctacttatgc     2760

taatacctct atttgatatc tgaagactat atgctaactg aaccttcctc aaatgttgtt     2820

atagtatcta tttttatata tttttttctt tttattcctc tctctaggga aatatgcctt     2880

cccttagcat gcattagaca taatgattta ataggtccct ttcatcttca tttaaatcta     2940

tcactattgc atggtaatga aaatattcct actataaatt ataaagggat atatatatat     3000

ggatatatat atgtatatac acatatatat atacacacac acacacatat atatatatat     3060

atatatatat acacatatac taataacttt tccctttttt cagcattttt gtctctatta     3120

ttattattgt ttttttccca ggtagggttt gtcttaggct gtagcctcta aggatagtta     3180

gttaatttgc actttgagac caaaggacat catgtgtgtc agtagggact gaatataaga     3240

tttatctcct ttgccacaca ttggtttatg atggagacat tgaaagtcta gtcatattcc     3300

tgaacagtaa aacctgtatt ttacctttta agtaagagga aatatgatat tcttattcaa     3360

acttaagttt agaatccaga atattactgt cgcacttttt ggtatcctga gtttccatag     3420

ggaactattg ggtttaaagt caccgttgga actacactgt gtgatcttat aaacttatgt     3480

tccctggcta tcatattctt ggctcagaac aatatttccc attactatct taagaattaa     3540

ggcattcatg gctcacgcct gtaatcccgg cactttggga ggccaaggca ggtggatcac     3600

gaggtcagag ttcaagacca gcctgaccaa gttggtgaaa ccccatcgct actaaaaata     3660

caaatattag gcgggtgtgg tggcgggtgc ctataatccc aactactcgg gagactgagg     3720

caaagaatcg cttgaacccg gtgggcggag gttgcagtga gccaagattg caccactgca     3780

ctccagcctg ggtgacagag caagattcca tctcaaaaaa aaaaaaaaaa aaaaaaaaaa     3840

agaattaaag cattcataca gtttagtgat tttgtttagt agtcggctat caattgctat     3900

caaatataac actgctgaaa tcagcagtgt gacttacctt gccattgtta aaatgttaca     3960

taaaacataa catgatagat gctaaggcct ttttttgcta taattcacca atagcaatca     4020

agcatgctaa cccatactga atgatattta cttgtagata tttcttcctt tccttgaaat     4080

tctcctttct atggaaagaa gatgaaccca aaaaagtgat aggaaatgtg gaatgctcat     4140

gcagatttag ctctgaaggc atatttaata actagtatgt cttgacaaca gtctttagat     4200

taaaaagaat tttcatggaa acatttaaca gaaagaacta gtaaaaagac actttgagtt     4260

agtccaggct taatgtgcaa tactgactct atactgatca taatttattt atgcgatcat     4320

attaatagac ctaatttcat taaaacaggt agaagatttt tcaaaagaaa gatgatgttt     4380

caaagctggt ctgccattct agatgagcct ccttgcttat ttaagttcca gtaggtgttc     4440

aaatgttaaa tgttaaacat aggtcatctt tgcttctgca gggcttcatc ttgcatgttt     4500

aagagaactt tgttttattt tgagggatta tttctctggg gatcattctt ataatacaag     4560

ccttaaatca ctaattttag tagcaataaa tgttaaaatt gaaaaaaaaa aaaaa          4615


<210>  352
<211>  2766
<212>  DNA
<213>  homo sapiens

<400>  352
gtcacgtgtc ccccccgcgg ggggcggccc ttgagggcgg cgcttccggt cggcggagcc       60

tggtggccgc agcggcggtg gcgacgacgg ccgagacgtg gggatggcgg gcgccgggag      120

cgaagcccgg ttcgccgggc tgtcgctggt gcagctcaac gagctgctgg aggacgaggg      180

ccagctgacg gagatggtgc agaagatgga ggagacacag aatgttcagc ttaacaaaga      240

aatgacactt gccagcaacc ggagcctggc agaaggaaac cttttgtacc agccccagct      300

ggacacgttg aaagcacgct tgacccagaa ataccaggaa ctccaggttc tctttgaagc      360

ctatcagata aagaagacca aattagacag acagtctagc agtgcttcct tggagaccct      420

gttagcactt cttcaggcag aaggggccaa gattgaggaa gacactgaga acatggcaga      480

gaagtttctg gatggagaac ttcctctgga ttccttcatt gatgtctatc agagcaaacg      540

gaaactggcc cacatgcgac gggtgaaaat cgagaagctc caggagatgg tcctaaaggg      600

gcagagactc ccacaggccc tggccccgct gccccccagg ctgcccgaac tggcacctac      660

cgcccccctt ccctaccctg ccccagaggc cagtgggcct cctgccgttg cacctcggcg      720

catccccccc ccaccacccc cggtgcctgc gggacgctta gccaccccgt ttactgcggc      780

catgagttcg ggacaggccg tgccgtaccc aggattacag tgcccgcccc tgcccccccg      840

cgtgggcctc cccactcagc aaggattctc ttcgcagttc gtgtccccat atccgccacc      900

tctccctcag agacccccgc cccggctccc tccacaccag ccgggtttca tcctccagtg      960

agcgccggcg cggtccttcc cgggagactt cttccacctg gcgtgttgtg ctctgctcac     1020

gggaaggagg ctggaggtcc gctctgtgcc aagggctctg gggccctggg ccagcgtgtc     1080

tgtctgattt tagaactgta ggtcagtggt gagtagtagg agcccaggct ttgggcatca     1140

aggcagttgt gtgtgccggg ttacagcctg acacctgtgc gttgcatcgg tttgcattat     1200

ccgtgtgatt tctaagtatc ttagcgttga tgaactcatg tttgggaaga aataggcctc     1260

tcccccagtc ccatttagaa tcgtggtcct tctgttgcag ctttatttaa tgagcatggt     1320

tcatgatact tattttattt tcgaaagaca gtcctatgtg tctcacccac cggccactgc     1380

agccctggtg agggcgggtg ggcgccggcc ggcctggaag agcgccgtgg ctgggccacc     1440

acctgtggct gcgttgttgc tcactgaatc tgttggggag aggtcaccat agtcaccgcc     1500

tgacctggct gctgctcttg cttcagagcc acaagcaaag tttgcactgg gcccactgcc     1560

gagtccagag gccggagaac ggccactggt gtgggagggg agcgcacgag tgggactttg     1620

cacagcaaat tgtgtcccca gctcctcctc tcccgcctgc ctggagccgg ccctgaaggt     1680

ttctatgaag aaataatccc ccaatatttt tactacgtgt gtgattttcc tgttttatat     1740

tgaaaaaact tttttgacac tcccaagacc attcagggaa attttataaa aaatgcagat     1800

actgtcttga gcagatcgaa atgccgatga agtggatgca atttcctttt gtgcaagcag     1860

tgcacggtgc ccccccctcg ggtgtccgtg ctgtgcctta gcttccccag gtgccgggac     1920

tcacacctgc taggggctgg gcaaggcccc ggctctgctt tctctgaagg gcttgtccaa     1980

gttcattgcc ctgttacagg tggtcaagac gtccggccgc cttgacccag gctaccctta     2040

gccaatatcc tctgcccctg ggtggctggt ggctgggcct cagggtgggc aacgttaggg     2100

gtttggcgaa agcccgcccc atgggattga gggacggggc tgcactccaa ccgtctgcac     2160

ctgctcttcc cccacccctg tgggacctca tcttcacgtg ccatgtgtgc tgaaggccca     2220

gggcccagca gggggcagtg gcacctgttg acggaaaagg ccgaggtgct taccagtgga     2280

ccttctggcc cgcccctccc ctgtcacttg tcgggcatcc agggccccga cctgtgccta     2340

gccgccaggg tgacagaagg cagaactgaa gcggggtctg ggccacgggc caggccactg     2400

ccttttgtcc tcagtgaccg tacattcctg ctctcggact tgaactctac tgtaactgtt     2460

ttcttaaagg aaatgaagct gtacaggacg attcactgcc atgccagtca ggcgggcttg     2520

ccatgttctg tgaatctcga gtgagcggtg ccacccgccc ccatacctcc gccaccggcc     2580

gctgtcgggg atgccacagc ctgccacggt cgcagccaga cgtgagcttg gcattgaagt     2640

tgcaaagcgg cccctggccg ggctcgccgt cgctgtccag ggccgtgtcc ggtgctgtgg     2700

ctgtaaagct gtaggaccct ttttaataaa tagagaatta ttaataacaa aaaaaaaaaa     2760

aaaaaa                                                                2766


<210>  353
<211>  2055
<212>  DNA
<213>  homo sapiens

<400>  353
gttgctatcc cagaatcctc agagaaggag tagcgcgttc gtgcgtccta gttccagtac       60

agcgtggagg gtttaggcag cgtgttctga ttctttgcgg gacggcgagc gcatttgtgc      120

tttgcccgcc gcggcctagg aggccttttg aggccgcgta gtcggtgttt ttgaactgac      180

tctacagctt ctggcaggcc gtgcggcgcc ctgacccggc ctcaccatgt tggtgctgtt      240

tgaaacgtct gtgggttacg ccatctttaa ggttctaaat gagaagaaac ttcaagaggt      300

tgatagttta tggaaagaat ttgaaactcc agagaaagca aacaaaatag taaagctaaa      360

acattttgag aaatttcagg atacagcaga agcattagca gcattcacag ctctgatgga      420

gggcaaaatc aataagcagc tgaaaaaagt tctgaagaaa atagtaaaag aagcccatga      480

accgctggca gtagctgatg ctaaactagg aggggtcata aaggaaaagc tgaatctcag      540

ttgtatccat agtcctgttg ttaatgaact tatgagagga attcgttcac aaatggatgg      600

attaatccct ggggtagaac cacgtgaaat ggcagctatg tgtcttggat tggctcacag      660

cctgtctcga tatagattga agtttagcgc tgataaagta gacacaatga ttgttcaggc      720

aatttccttg ttagatgact tggataaaga actaaacaac tacattatgc gatgtagaga      780

atggtatggc tggcatttcc ctgaattagg aaaaattatt tcagataatt taacatactg      840

caagtgttta cagaaagttg gcgataggaa gaactatgcc tctgccaagc tttctgagtt      900

gctgccagaa gaagttgaag cagaagtgaa agcagctgca gagatatcaa tgggaacaga      960

ggtttcagaa gaagatattt gcaatattct gcatctttgc acccaggtga ttgaaatctc     1020

tgaatatcga acccagctct atgaatatct acaaaatcga atgatggcca ttgcacccaa     1080

tgttacagtc atggttgggg aattagttgg agcacggctt attgctcatg caggttctct     1140

tttaaatttg gccaagcatg cagcttctac cgttcagatt cttggagctg aaaaggcact     1200

tttcagagcc ctcaaatcta gacgggatac ccctaagtat ggtctcattt atcatgcttc     1260

actcgtgggc cagacaagtc ccaaacacaa aggaaagatt tctcgaatgc tggcagccaa     1320

aaccgttttg gctatccgtt atgatgcttt tggtgaggat tcaagttctg caatgggagt     1380

tgagaacaga gccaaattag aggccaggtt gagaactttg gaagacagag ggataagaaa     1440

aataagtgga acaggaaaag cattagcaaa aacagaaaaa tatgaacaca aaagtgaagt     1500

gaagacttac gatccttctg gtgactccac acttccaacc tgttctaaaa aacgcaaaat     1560

agaacaggta gataaagagg atgaaattac tgaaaagaaa gccaaaaaag ccaagattaa     1620

agttaaagtt gaagaagagg aagaagaaaa agtggcagaa gaagaagaaa catctgtgaa     1680

gaagaagaag aaaaggggta aaaagaaaca cattaaggaa gaaccacttt ctgaggaaga     1740

accatgtacc agcacagcaa ttgctagtcc agagaaaaag aagaaaaaga aaaaaaagag     1800

agagaacgag gattaacaga aaggaattac gattatatca cccggacaca catcatgctt     1860

aagattcaac tgggagcata ccagggatgc tctctaacgt aatcaaggga aggttcagta     1920

agacaaagtg atttatcatc tataacttca aacctatttg tcttgacatc aactctgtta     1980

accttatgtc atcatttctt agagtctttg atatacaaat aaaattttct ttgtatttta     2040

aaaaaaaaaa aaaaa                                                      2055


<210>  354
<211>  2707
<212>  DNA
<213>  homo sapiens

<400>  354
gagcggtcac gtgtgagggg cggcccgagg tcacgtgacg gagcgccgga gcggagggag       60

ccggggctgg gagttctcct gagggaagag gagtggagta ggggggacgc ggcggcggcg      120

ttgacaatga gttttcttgg aggctttttt ggtccaattt gtgagatcga tattgttctt      180

aatgatgggg aaaccaggaa aatggcagaa atgaaaactg aagatggcaa agtagaaaaa      240

cactatctct tctatgacgg agaatccgtt tcaggaaagg taaacctagc ctttaagcaa      300

cctggaaaga ggctagaaca ccaaggaatt agaattgaat ttgtaggtca aattgaactt      360

ttcaatgaca agagtaatac tcatgaattt gtaaacctag tgaaagaact agccttacct      420

ggagaactga ctcagagcag aagttatgat tttgaattta tgcaagttga aaagccatat      480

gaatcttaca tcggtgccaa tgtccgcttg aggtattttc ttaaagtgac aatagtgaga      540

agactgacag atttggtaaa agagtatgat cttattgttc accagcttgc cacctatcct      600

gatgttaaca actctattaa gatggaagtg ggcattgaag attgtctaca tatagaattt      660

gaatataata aatcaaagta tcatttaaag gatgtgattg ttggaaaaat ttacttctta      720

ttagtaagaa taaaaataca acatatggag ttacagctga tcaaaaaaga gatcacagga      780

attggaccca gtaccacaac agaaacagaa acaatcgcca aatatgaaat aatggatggt      840

gcaccagtaa aaggtgaatc aattccaata aggctatttt tagcaggata tgacccaact      900

ccaacaatga gagatgtgaa caaaaaattt tcagtaaggt actttttgaa tttagtgctt      960

gttgatgagg aagaccggag gtacttcaaa cagcaggaga taattttatg gagaaaagct     1020

cctgaaaaac tgaggaaaca gagaacaaac tttcaccagc gatttgaatc tccagaatca     1080

caggcatctg ccgaacagcc tgaaatgtga actgaacagg agaaaaaaag aaaagcaaaa     1140

aactcctgta acccttgaga ttaagttcag caggttaaag atggttgcag ctggaggggg     1200

cggaaaaagg ccaaaactcc atatatgtta gtcttccttt atcttacagc gcagcattta     1260

ttttatgata taatgaaatg ttcgttcatg tatatacatt tttaaaagtg ctttctttga     1320

aacactggaa ctttgttaag ctgccttttt ttttttaact tcctactttg atgataagca     1380

ctcagatata tatcagcgta aacatgaaaa attttcatgt gagtaggctg gtatttgtaa     1440

ttttgctttc tttctgcata atgttgatta taaatcctct cttttcaggc taatgattac     1500

ctcttattct ctacatgcaa aaaattaaat attttgtgtt caaataaaat tagaaaacct     1560

gagtggcctc ttgtgtcctg cagagattta aaacatggca tctcaatatt tttgagaact     1620

acatttgttt ttaacatatg tgtttgagaa aagcatatgg agtgtttcac cgcaggcact     1680

tctgagtacc attccatggc ttccagaatt ttatcctctt tgaggtcttc tgtgctatga     1740

atattagatt tctttcccca agggattatg tggcaggtca ttatggcctt cttttttttg     1800

gccatattaa gtaacagttt tgctatattc cagtagtacc gttgtgtgtt ttctgcaatg     1860

tggagttgac ttagcttggc attttagatt tgttaaaact attttttcca taaatacttt     1920

gaaacatatt tatatatttc aatttaagga atctttttgc catgtgtatg caaatattat     1980

tttcttcata cattcatttt cttttcaggg gaaaattttg ggatggggga ctcaggagga     2040

cctgtgaagc atgtagttat ctagatctgg gtaatttcat gtttattaaa ctcgaacttt     2100

ggctagttaa actcatattg aaacttcatc tagtctctta attttttaac actaaattca     2160

agtcatttgt tttaagtctc taaaaaagaa gattgcagtc atccattcat atgcatgggg     2220

tctgatcgca aatacactaa atgtggagtg taggaaccaa aatgaaacct gctgtatgga     2280

aactactttc acttatggtt cattggtttt tgtaccaata ttttttatgc acttcagtgc     2340

aagtcttgtc agttaacctt actttatgag taagctaaat aacccaaatt acatttcttt     2400

aaacctgttt tactactatg gcactttgat aaaatggtca ggaaccaact ttactggcaa     2460

aagggtccat gtaccaccat gtgctggagc atctgttcta catgtggata tctatgaatg     2520

gtaatgtttt ccttcatgta agtgcctatt cagagtttca gaattttaaa atgccaaata     2580

ttttcatggt catttgcatg tagtaagcca gaaaatattc aaagagattt tgaaaaccaa     2640

ttgtatttaa ccagcctcaa attgtgcaac catgatgtat aataaagaat ttgaaacaga     2700

aaaaaaa                                                               2707


<210>  355
<211>  3734
<212>  DNA
<213>  homo sapiens

<400>  355
cctctttctc ccccctctct ccctcctctc ctctctctct cctctcttct ctgaacctct       60

cttctctttc tcttttctta catattctac tagttgtttt ccccttcttc ttctcctttc      120

tctccttttt ctccctcctc cttgtctctt ttactccatt cctgcagaag agagagggct      180

aaacttaaag aaaaaaaaaa ggaggaggag gaggaggagg cacccccttc gtattcttct      240

tatcgttatt ttatacatat atgatttttt ttggagggag ggtgttggtt gccggctgaa      300

gagcacttat ttaaaatact aaaaaaagaa catttttggg cgatctccag ggttttttta      360

actagctctg tgtgttatag cagaagaagc agaagaagga gcaagaaaga ggaaaagaag      420

aggattattt attcgaccta ctttggatgt ctctctcgct tttccttttt cctttttttg      480

gcaattattt tcttctgatt tttatttttt ctatttcgct gtgatttcgt cgccggcgtg      540

aattatcccg tatttttctc ccccttccgt cacctcccga aagaagaagg cagcgagagc      600

ccggcgccac cggcacaaca aaaagagcaa agtgtgtgat cttcctcgcc ggctgcctcc      660

cgctctccag cgctgccttc ctgaatggct ggctgcgtcc ggccctggac ctggcccccc      720

gacacccgcg cgccctgatc gccggcggca gcctcgccca gcgccctgct cggctcaccg      780

cgctccccgc actcccgagc ccggcgaggg ctcccgccgg gacagcggcg gcgccgcggg      840

cggccccggc ctccgctcgc gctccggctg cggccccgac tcctgctcgg actccggccc      900

gggtcccggc tcctccagcg gcgctcgccg cagcagctcc ggcggcagct ccagcggcgc      960

ctgcagccgc gacctcctcc tcctccgccg ccgccgccgc ctccgccctc gccggcttcc     1020

tctatgtcgg ctcagcccgc gcgctgcgcg tagcccgagc ggccggcggg cgggcgcccg     1080

gcgcgggtga gcgactgtgt gtgcgagtgt gtgtgtgcgc gggggtgcgg gcgaggcgga     1140

gggcgagtgt gtgcgcgcgc cgtggcccat gcccgccgcc cccggcgctg cgccccgcgc     1200

cgctcccggc tgccgcctgt gccatttctg attttgcaac ttggggaaga agaaaaaagc     1260

gagagaaggg agcttgctcg ccggggggtg gggagggggg aaggagagcg cggccccccc     1320

aggaacggag cgcgggggga gcgggcgagg ggagcagggg tgttgggggg ggagcctgag     1380

agcctggggg ggctgcaaaa agagagaaag aaaacagcag gaaccacaac aaaacgccag     1440

cagggcgggc gggcgcgcag cagcagcggg gcggccgagg cagtagcggc ggcagcggcg     1500

gcggcggcgg aggcagcggc cggtgtccgg ctcgggctcg gctcctgcga ccccggggcg     1560

cccggcgggc cccccgcccc ctccccctcc ccccttcccc ttccccttcc cctcccagcg     1620

cgcccgcgcg ccccgcggcc ctcggcgagc agctcggctc cccccagcgc tccccgggcc     1680

caaagatatg gcaatggtag ttagcagctg gcgagatccg caggacgacg tggccggggg     1740

caaccccggc ggccccaacc ccgcagcgca ggcggcccgc ggcggcggcg gcggcgccgg     1800

cgagcagcag cagcaggcgg gctcgggcgc gccgcacacg ccgcagaccc cgggccagcc     1860

cggagcgccc gccacccccg gcacggcggg ggacaagggc cagggcccgc ccggttcggg     1920

ccagagccag cagcacatcg agtgcgtggt gtgcggggac aagtcgagcg gcaagcacta     1980

cggccaattc acctgcgagg gctgcaaaag tttcttcaag aggagcgtcc gcaggaactt     2040

aacttacaca tgccgtgcca acaggaactg tcccatcgac cagcaccacc gcaaccagtg     2100

ccaatactgc cgcctcaaga agtgcctcaa agtgggcatg aggcgggaag cggttcagcg     2160

aggaagaatg cctccaaccc agcccaatcc aggccagtac gcactcacca acggggaccc     2220

cctcaacggc cactgctacc tgtccggcta catctcgctg ctgctgcgcg ccgagcccta     2280

ccccacgtcg cgctacggca gccagtgcat gcagcccaac aacattatgg gcatcgagaa     2340

catctgcgag ctggccgcgc gcctgctctt cagcgccgtc gagtgggccc gcaacatccc     2400

cttcttcccg gatctgcaga tcaccgacca ggtgtccctg ctacgcctca cctggagcga     2460

gctgttcgtg ctcaacgcgg cccagtgctc tatgccgctg cacgtggcgc cgttgctggc     2520

cgccgccggc ctgcatgcct cgcccatgtc tgccgaccgc gtcgtggcct tcatggacca     2580

catccgcatc ttccaggagc aggtggagaa gctcaaggcg ctacacgtcg actcagccga     2640

gtacagctgc ctcaaagcca tcgtgctgtt cacgtcagac gcctgtggcc tgtcggatgc     2700

ggcccacatc gagagcctgc aggagaagtc gcagtgcgca ctggaggagt acgtgaggag     2760

ccagtacccc aaccagccca gccgttttgg caaactgctg ctgcgactgc cctcgctgcg     2820

caccgtgtcc tcctccgtca tcgagcagct cttcttcgtc cgtttggtag gtaaaacccc     2880

catcgaaact ctcatccgcg atatgttact gtctgggagc agcttcaact ggccttacat     2940

gtccatccag tgctcctaga ccttgggcgc ttcccacctg ccccgtcccc ctagagactc     3000

agaggaccca cctgggccaa ggactccaaa gccgcgggga caccgggaag tgcagcgggc     3060

caggcaggct gggtgggagg gaggagggcc gagacaggag cagcccaccc agcagaaata     3120

caatccgagc tacaaagcat gggaaaaaga gactctttta ggatcagatc tgtgagcacg     3180

ttggcgagga aaaacaaaac aaacaaaaaa aagaaccttg tgtctgtctg gtgaaaaaaa     3240

gaaaaacaaa ttggaagaga ggaccatgag aattttaata aaacagaagg aaactaatgg     3300

accttccagg atttattgtg gacggatgtg gatatattct gtacaggaac aacacatatg     3360

gaagtggact gaagcctatg tagaaacaca cacacactga acattgttat tcattttgta     3420

aaatactagt ctttattttc attttttgta aaatttaaac atcgtatgcg cataaagaaa     3480

aaggaaacaa gaattagggg aaaataacat tttccaaata attataaaaa attgtcctgt     3540

gtctatgtat ctatatctgt tttgtatttt tttctggttc caaaccagat ttcctgtgat     3600

tctatactaa taatttttga tataaccctt tgcttcttat aatgagtgcg atatatgttg     3660

tcgaggctgt tcttcaagaa ttaaaattga agtgaaaatt taaacaaaaa taaaagaatt     3720

tagcaaaaaa aaaa                                                       3734


<210>  356
<211>  1099
<212>  DNA
<213>  homo sapiens

<400>  356
actggtgacg tagatctcat gtgaccagga gtcgacgtgt gcagaagtcc tggtaatctg       60

gtccttgttc ccgtctggat accagcttcc ttcagcagcg caggcggtgg tccctgaggc      120

ccgtggaagg agtcaaactt gcgggaattt tgcagtttat ctgcagggct gttgtttcca      180

gcaagaccca aagctagaaa aggaggagga agaaactgac ccgatcagtg ccagtcattg      240

tattcaaaga agaataagca agaaagaaaa gaaggaagga agagaggtag acagatacaa      300

gatgaaatcc tgtcaaaaaa tggaaggaaa accagaaaat gagagtgaac caaagcatga      360

ggaagagcca aagcctgagg aaaagccaga agaggaggag aagctagagg aggaggccaa      420

agcaaaagga acttttagag aaaggctgat tcaatctctc caggagttta aagaagatat      480

acacaacagg catttaagca atgaagatat gtttagagaa gtggatgaaa tagatgagat      540

aaggagagtc agaaacaaac ttatagtgat gcgttggaag gttaatcgaa accatcctta      600

cccctattta atgtagttta ccttgatttt tatctgatat taacaatacc atatagcttg      660

ctttttatta gcatttcctg atattccttt gtccatattt ctacttataa cctgttgcta      720

ttaatggttt tagatgtatc tcttgttatc tgcatctcat tgtttattgt attttgaacc      780

aatctacaag tctctgtctt ttaataaaag aactttacac atttgtaaaa aagaggttct      840

tggtaagata taaaatggaa aaaggctaag taatatgtga atatcatatt tttgaaaggt      900

aaaaagtaca tttgtatatt acatatatgg acataacttg tgaaggatga aagaaagtac      960

agcctctcgg tggtgggatt atgaatgatt tttctccttt tgcttgtttg tattttctat     1020

attcctaaaa ttaacacaca ttattattgc tagaataata aaagttttat aaaaaagaag     1080

caacaaaaaa aaaaaaaaa                                                  1099


<210>  357
<211>  2403
<212>  DNA
<213>  homo sapiens

<400>  357
aagctttgaa ccgagtttgg ggagctcagc agcatcatgc ttagactttt caaagagaca       60

aactccattt tcttatgaat ggaaagtgaa aacccctgtt ccgcttaaat tgggttcctt      120

cctgtcctga gaaacataga gacccccaaa agggaagcag aggagagaaa gtcccacacc      180

cagaccccgc gagaagagat gaccatgacc accatgccag aaagtctcaa cagccccgtg      240

tcgggcaagg cggtgtttat ggagtttggg ccgcccaacc agcaaatgtc tccttctccc      300

atgtcccacg ggcactactc catgcactgt ttacactcgg cgggccattc gcagcccgac      360

ggcgcctaca gctcagcctc gtccttctcc cgaccgctgg gctaccccta cgtcaactcg      420

gtcagcagcc acgcatccag cccctacatc agttcggtgc agtcctaccc gggcagcgcc      480

agcctcgccc agagccgcct ggaggaccca ggggcggact cggagaagag cacggtggtg      540

gaaggcggtg aagtgcgctt caatggcaag ggaaaaaaga tccgtaaacc caggacgatt      600

tattccagtt tgcagttgca ggctttgaac cggaggttcc agcaaactca gtacctagct      660

ctgccggaga gggcggagct cgcggcctct ttgggactca cacagactca ggtcaagatc      720

tggttccaaa acaagcgatc caagttcaag aagctgatga agcagggtgg ggcggctctg      780

gagggtagtg cgttggccaa cggtcgggcc ctgtctgctg gctccccacc cgtgccgccc      840

ggctggaacc ctaactcttc atccgggaag ggctcaggag gaaacgcggg ctcctatatc      900

cccagctaca catcgtggta cccttcagcg caccaagaag ctatgcagca accccaactt      960

atgtgaggtt gcccgcccgt ctccttcttg tctccccggc ccaggtccct cccgcctcca     1020

ggtccatcca tcccgtccgg aaaagaagga cccagaggga agaaggaaca gtggaggcgg     1080

gacgccctcc atctcctcgg agccccgcga ggtccggccc agcaacttcc cggcatccgc     1140

gctctagcct gaaccctggc ctgggccgag cagtggcagc agagagtggc ctcggaggga     1200

agccactgcc acctgagaca gcccaagcag caagataaac ccgctccacc cgacccgccg     1260

accttcagct ttgtgggact atcaggaaaa aacaaaacaa aaacaaaatg tagaaaaagc     1320

aaaagctctt ttctgtcctg tcagtctcct gtctcctttt gctctgtctg tgcgctggta     1380

aagtccaggt cctcatccgt ccgctgtcct cattctgcgg cctcagcaaa aagccacaag     1440

gtctgagcgg cccgggtcct gccgggctga ccatctccgg atcctgggac actctgcctg     1500

accatctgtg tagctggtgt gggaatctgg gggcattgga gggagggggt tttatttatt     1560

gagaaatgga cttcgcctga ggctgtttgc caattcaggg ttctgctggg cgcaaggaac     1620

gcactgttca aacgcactgt ttactttaag cgcacgggga gaaacgaata aggaggacgt     1680

ggtgattttt aatttataca gtaacttttg tacttctctg gtatggagag tttggagccg     1740

aatgatttgc attttttaca tgtccgacat tatttaataa ataattttta aaagaaaaga     1800

acgataaatg aagccaacat gattttctca tttcgggagg aactctgttg cttcgcctgg     1860

acaagaagga aaatgctgat ttcctccttg ggtagaaaga gggagcgagg gcaaatgggg     1920

agtagagaga aaacaggcga gaacaagcac tctaattcca gtgggcttta aaataagaca     1980

aaatcagctt tacaacaatc cctagaggct cgaccacaga ataatgccag tcaccaccct     2040

gaacgcacaa tctccagtgc aggatctaat gactgtacat attattgtta ttattattat     2100

tgttattatt gttgttctgt aaacatgttg cacaagctta gcctttttgc gttctgttgt     2160

gtgtggctgt aaaaccccat gctttgtgaa atgagaatct tgacattttt cttgtgaaat     2220

ttggaaaatg tgatcaattg aaatcaactg tgttttgtgt tctctatgtc aaagtttagt     2280

tttatattga gaatgttaac ttattgcttt gtatcttggg aaaaaaactt tgtaaataag     2340

ttataaagtt tctttgagac agtaaaatta tgatttcttg aaaaaaaaaa aaaaaaaaaa     2400

aaa                                                                   2403


<210>  358
<211>  1121
<212>  DNA
<213>  homo sapiens

<400>  358
gccccgtcgg gggcccggag ggggactcgg agcgggccaa ggggcggctc cggcgggcgg       60

actcggagcg ggcggcggag tgacccggac agctgtcctc tctgacacca ccccggcctg      120

cctctttgtt gccatgagag ctgcctacct cttcctgcta ttcctgcctg gcttgctggc      180

tcagggccag tatgacctgg acccgctgcc gccgttccct gaccacgtcc agtacaccca      240

ctatagcgac cagatcgaca acccagacta ctatgattat caagaggtga ctcctcggcc      300

ctccgaggaa cagttccagt tccagtccca gcagcaagtc caacaggaag tcatcccagc      360

cccaacccca gaaccaggaa atgcagagct ggagcccaca gagcctgggc ctcttgactg      420

ccgtgaggaa cagtacccgt gcacccgcct ctactccata cacaggcctt gcaaacagtg      480

tctcaacgag gtctgcttct acagcctccg ccgtgtgtac gtcattaaca aggagatctg      540

tgttcgtaca gtgtgtgccc atgaggagct cctccgagct gacctctgtc gggacaagtt      600

ctccaaatgt ggcgtgatgg ccagcagcgg cctgtgccaa tccgtggcgg cctcctgtgc      660

caggagctgt gggagctgct agggtggtgc tggcatcctg agtcctggcc ctcctgggat      720

ctggggccct cgggccctgc ctgacctggt gcttttttcc ccatccccat gttcctttta      780

ttctgtaaaa agttagtgga ctgcagccct gggggttgca ggctgcggtg cctcaggccc      840

ctccttcagc ctgtggccac ctctggggca caatgggggc tccccactgc ccagtctgcc      900

cctcgggttg ggggagtatc ccaggcctct ctgtgggacc tgggcccctg acgggccttc      960

tcagcccgtt ttgaggacag acagtccccc gaggtaggct acatcccccc accccagctg     1020

gtctgcttgg atttcctaca gcccccgtgg gcatggacca cctttatttt atacaaaatt     1080

aaaaacaagt ttttacaaaa aaaaaaaaaa aaaaaaaaaa a                         1121


<210>  359
<211>  2651
<212>  DNA
<213>  homo sapiens

<400>  359
gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt       60

ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt      120

gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca      180

gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc      240

tctgagtcag gaaacatttt cagacctatg gaaactactt cctgaaaaca acgttctgtc      300

ccccttgccg tcccaagcaa tggatgattt gatgctgtcc ccggacgata ttgaacaatg      360

gttcactgaa gacccaggtc cagatgaagc tcccagaatg ccagaggctg ctccccccgt      420

ggcccctgca ccagcagctc ctacaccggc ggcccctgca ccagccccct cctggcccct      480

gtcatcttct gtcccttccc agaaaaccta ccagggcagc tacggtttcc gtctgggctt      540

cttgcattct gggacagcca agtctgtgac ttgcacgtac tcccctgccc tcaacaagat      600

gttttgccaa ctggccaaga cctgccctgt gcagctgtgg gttgattcca cacccccgcc      660

cggcacccgc gtccgcgcca tggccatcta caagcagtca cagcacatga cggaggttgt      720

gaggcgctgc ccccaccatg agcgctgctc agatagcgat ggtctggccc ctcctcagca      780

tcttatccga gtggaaggaa atttgcgtgt ggagtatttg gatgacagaa acacttttcg      840

acatagtgtg gtggtgccct atgagccgcc tgaggttggc tctgactgta ccaccatcca      900

ctacaactac atgtgtaaca gttcctgcat gggcggcatg aaccggaggc ccatcctcac      960

catcatcaca ctggaagact ccagtggtaa tctactggga cggaacagct ttgaggtgcg     1020

tgtttgtgcc tgtcctggga gagaccggcg cacagaggaa gagaatctcc gcaagaaagg     1080

ggagcctcac cacgagctgc ccccagggag cactaagcga gcactgccca acaacaccag     1140

ctcctctccc cagccaaaga agaaaccact ggatggagaa tatttcaccc ttcagatgct     1200

acttgactta cgatggtgtt acttcctgat aaactcgtcg taagttgaaa atattatccg     1260

tgggcgtgag cgcttcgaga tgttccgaga gctgaatgag gccttggaac tcaaggatgc     1320

ccaggctggg aaggagccag gggggagcag ggctcactcc agccacctga agtccaaaaa     1380

gggtcagtct acctcccgcc ataaaaaact catgttcaag acagaagggc ctgactcaga     1440

ctgacattct ccacttcttg ttccccactg acagcctccc acccccatct ctccctcccc     1500

tgccattttg ggttttgggt ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac     1560

ccaggacttc catttgcttt gtcccggggc tccactgaac aagttggcct gcactggtgt     1620

tttgttgtgg ggaggaggat ggggagtagg acataccagc ttagatttta aggtttttac     1680

tgtgagggat gtttgggaga tgtaagaaat gttcttgcag ttaagggtta gtttacaatc     1740

agccacattc taggtagggg cccacttcac cgtactaacc agggaagctg tccctcactg     1800

ttgaattttc tctaacttca aggcccatat ctgtgaaatg ctggcatttg cacctacctc     1860

acagagtgca ttgtgagggt taatgaaata atgtacatct ggccttgaaa ccacctttta     1920

ttacatgggg tctagaactt gacccccttg agggtgcttg ttccctctcc ctgttggtcg     1980

gtgggttggt agtttctaca gttgggcagc tggttaggta gagggagttg tcaagtctct     2040

gctggcccag ccaaaccctg tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa     2100

tctcacccca tcccacaccc tggaggattt catctcttgt atatgatgat ctggatccac     2160

caagacttgt tttatgctca gggtcaattt cttttttctt tttttttttt ttttttcttt     2220

ttctttgaga ctgggtctcg ctttgttgcc caggctggag tggagtggcg tgatcttggc     2280

ttactgcagc ctttgcctcc ccggctcgag cagtcctgcc tcagcctccg gagtagctgg     2340

gaccacaggt tcatgccacc atggccagcc aacttttgca tgttttgtag agatggggtc     2400

tcacagtgtt gcccaggctg gtctcaaact cctgggctca ggcgatccac ctgtctcagc     2460

ctcccagagt gctgggatta caattgtgag ccaccacgtc cagctggaag ggtcaacatc     2520

ttttacattc tgcaagcaca tctgcatttt caccccaccc ttcccctcct tctccctttt     2580

tatatcccat ttttatatcg atctcttatt ttacaataaa actttgctgc cacctgtgtg     2640

tctgaggggt g                                                          2651


<210>  360
<211>  945
<212>  DNA
<213>  homo sapiens

<400>  360
ccaagcgcgg ggccggagcg gccttcccgg agtcctttgc gcggcacctg gcgacaaaat       60

ggctgcccga gggagacggg cggagcctca gggccgggag gctccgggcc ccgcgggcgg      120

tggcggtggc gggagccgtt gggctgagtc gggatcgggg acgtcgcccg agagcgggga      180

cgaggaggtg tcgggcgcgg gttcgagccc ggtgtcgggc ggcgtgaact tgttcgccaa      240

cgacggcagc ttcctggagc tgttcaagcg gaagatggag gaggagcagc ggcagcggca      300

ggaggagccg cccccgggtc cgcagcgacc cgaccagtcg gccgccgccg ctggccccgg      360

ggatccgaag aggaagggcg gtccgggctc cacacttagc ttcgtgggca aacgcagagg      420

cgggaacaaa ctagccctca agacgggaat agtagccaag aagcagaaga cggaggatga      480

ggtattaaca agtaaaggtg acgcgtgggc caagtacatg gcagaagtga aaaagtacaa      540

agctcaccag tgcggtgacg atgataaaac tcggcccctg gtgaaatgac gcccctcccc      600

cacctgccca tggcctggga ctctctgcga tgtacataac tatttaatgc agcggcagcg      660

gcgacagcct tccctgagag gacttaaaag cagaaggaaa ccgagatgct tcccgcagcc      720

gtggacgatt ctccaggact ctttttttac cttgagcact tgcctcgtga gacttcatag      780

aacagtggtt tactgtcccc cccttctcac ctcctcattc tctctggctc tttctgtctt      840

cctcttctca ccctcctccc tccccttagc catcacttct gggaagtaaa gaacttgact      900

tagtgccgga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                      945


<210>  361
<211>  945
<212>  DNA
<213>  homo sapiens

<400>  361
ccaagcgcgg ggccggagcg gccttcccgg agtcctttgc gcggcacctg gcgacaaaat       60

ggctgcccga gggagacggg cggagcctca gggccgggag gctccgggcc ccgcgggcgg      120

tggcggtggc gggagccgtt gggctgagtc gggatcgggg acgtcgcccg agagcgggga      180

cgaggaggtg tcgggcgcgg gttcgagccc ggtgtcgggc ggcgtgaact tgttcgccaa      240

cgacggcagc ttcctggagc tgttcaagcg gaagatggag gaggagcagc ggcagcggca      300

ggaggagccg cccccgggtc cgcagcgacc cgaccagtcg gccgccgccg ctggccccgg      360

ggatccgaag aggaagggcg gtccgggctc cacacttagc ttcgtgggca aacgcagagg      420

cgggaacaaa ctagccctca agacgggaat agtagccaag aagcagaaga cggaggatga      480

ggtattaaca agtaaaggtg acgcgtgggc caagtacatg gcagaagtga aaaagtacaa      540

agctcaccag tgcggtgacg atgataaaac tcggcccctg gtgaaatgac gcccctcccc      600

cacctgccca tggcctggga ctctctgcga tgtacataac tatttaatgc agcggcagcg      660

gcgacagcct tccctgagag gacttaaaag cagaaggaaa ccgagatgct tcccgcagcc      720

gtggacgatt ctccaggact ctttttttac cttgagcact tgcctcgtga gacttcatag      780

aacagtggtt tactgtcccc cccttctcac ctcctcattc tctctggctc tttctgtctt      840

cctcttctca ccctcctccc tccccttagc catcacttct gggaagtaaa gaacttgact      900

tagtgccgga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                      945


<210>  362
<211>  4009
<212>  DNA
<213>  homo sapiens

<400>  362
ggccggcggc cacgtgaccc accgcggcgg ggccggcggc ccagaaatag cagcggcggc       60

ggttccgccc gcgggcggcg cgagcgaggg gcagaggcga gagacgccgg cggggcgcgg      120

gcgcggcggc cccggaggat gctgctgagc cccggcactg cctggctgcg agcacatgat      180

ggcgatacgg gagctcaaag tgtgccttct cggggacact ggggttggga aatcaagcat      240

cgtgtgtcga tttgtccagg atcactttga ccacaacatc agccctacta ttggggcatc      300

ttttatgacc aaaactgtgc cttgtggaaa tgaacttcac aagttcctca tctgggacac      360

tgctggtcag gaacggtttc attcattggc tcccatgtac tatcgaggct cagctgcagc      420

tgttatcgtg tatgatatta ccaagcagga ttcattttat accttgaaga aatgggtcaa      480

ggagctgaaa gaacatggtc cagaaaacat tgtaatggcc atcgctggaa acaagtgcga      540

cctctcagat attagggagg ttcccctgaa ggatgctaag gaatacgctg aatccatagg      600

tgccatcgtg gttgagacaa gtgcaaaaaa tgctattaat atcgaagagc tctttcaagg      660

aatcagccgc cagatcccac ccttggaccc ccatgaaaat ggaaacaatg gaacaatcaa      720

agttgagaag ccaaccatgc aagccagccg ccggtgctgt tgacccaagg gccgtggtcc      780

acggtacttg aagaagccag agcccacatc ctgtgcactg ctgaaggacc ctacgctcgg      840

tggcctggca cctcactttg agaagagtga gcacactggc tttgcatcct ggaagacctg      900

cagggggcgg ggcaggaaat gtacctgaaa aggattttag aaaaccctgg gaaaacccac      960

cacaccacca caaaatggcc tttagtgtat gaaatgcaca tggaggggat gtagttgcat     1020

ttttgctaaa aaaaaaaaaa aacctttaaa aattgttgga tgtgtacaaa agtcttactg     1080

ccttattatg tgtatgggat tctaaagtgg cattccactt ggatttcctg tgctacctat     1140

ccaaattcca gtaactactt cagtgtcatt gcctttgtta cctaaccaac cttcactgaa     1200

aggcaaattt agttcaggag gttagttttt agctagcttt ggaagtaagc ctttatttat     1260

tactttttgg aggaaatcag agaagtgtca atggaccgtc actcagactg agacttgagt     1320

tattacagaa gccaggaaaa gtgtattaga aactgttgtc tacaccactt ttaattggtg     1380

aacaattttt ctaagttatg gtcatatata cccaaacaaa ccaaatcaaa ctaaattact     1440

gcatataatt ttgggattgg gtggcctagt ttgaaagagt gatttaagta atcactatgt     1500

aagtggtgag agatgcagga catacacatt attcaagaga ccacctgaca tgcatctcct     1560

ccgcaggaat acattcgtcc tctcttagag aagtttaacg cacatagtat tattttacta     1620

agagaatatc tcttggtgtc atatctaggg gaagagaatt aactagaatt aaatttaatg     1680

tttgaatcta aatcattggg caaacttcta ataataacaa ttaataatag gttacaggaa     1740

agccagccag aggaagtgtc agcactttaa aattctagac cccaaaaaac tacaaaatca     1800

gaaaaagtat ttttatgttt ctagcttgag gagaagggct ttagggctaa ccagaggtct     1860

gaccctagaa tgccaaggaa ctgagaatgg gctccgatga aaaccttcct tttcagattc     1920

cctgtctgct caattaaaga tgtttgaatc caaaggaagt caaggaagaa aaagcatgga     1980

aaggaagaga actgattcct actgaaaatt caaattctat taccattcta actttcataa     2040

aaagttggga tcaagaagca gctgatttcc tgccagggct tatattaggg ggtgattctt     2100

aaaggacatt aggattggtg ctcagaaatg gttaatcatg ctgtgtgcta gccagggcca     2160

gctggtacct tctttgccat gagcattcaa gggacggcta acctttattg acaatctata     2220

tcgcaaaagt caggaaagag gttgtgagct gattggatta aagacctggc acttcagtaa     2280

ctcagcacgc ttccacttca ctcaacttaa gagagttcat tgacagtgtt aggatgtgaa     2340

ggctgggaaa cacttatttt gcttcaagag ttccacttgg ctctcccaaa taggtacctc     2400

aaaaactgtt agcaagcggc atttggatgt cttgacaggg gctttgcagg gatttttagg     2460

gttttttcca cattgtccac attaatggtt ggcatgattg tgcttgcagg ccaagaaatg     2520

atcatacccc ttgccaaagg taaaaaaaaa aaaaaaaaaa tgagttgaaa attgaagtga     2580

cctctttcca gctgagttgc aggcttattt tgtaaccttt cctcatccag ttttccctga     2640

gaacctgggt ttatctctag atagctgttc aggtttttta gctgaggggt aagtatccta     2700

gctgagagtt ttgcatcttt gggctgggtt tgcagtggtt gtgttttgca taaaatgtct     2760

agtctttgcc acagatagtg agctacccac taatgagccc atggttttat ttcagaagca     2820

catgagggtg tgaaaccact ctgttacctt tctgtattgt cttagctatt caagccagtc     2880

agaggataat atatatattc tcatcagcac tcagagtagt cagtgaagag agtagatcac     2940

acttgggcac accaggattc acataaacat tgtatcttct ctgtggatgc tcaggccttg     3000

tctacaatga ggctttacaa ccttcctttg ttttggctcg ggattacttc ctggctgtct     3060

aataattgaa ccataaccat gtaatattat gtaaaggcct ggaaattact gttgctaaaa     3120

aaagtcatgt agtttcatgt agtgtagcat ccttggcatc gttttccaaa atttgttcct     3180

tctccctttt ttttttcttt cgtgtgtggc atgagtgtgt atctgtgtaa atatgattgt     3240

atatgtgtta ctccgatatg taatccattt cactggctga gtttggcccc tagccatgtg     3300

ttaatataaa gtaggcatgg cttcccaatg gaaatctctg agaatgacag tggagttgtg     3360

caagcatttt acattgccac ataattgact tgccatttta tggttaaaaa cggcacatta     3420

ggcagttgaa tatgacgtta ccttgcagac taaaaggttg aaggcccgaa actaactttt     3480

agctaacaat aagggctgtg ccccaatgga aactgagttc attttctgag aaaggtttgg     3540

atgactgaaa tatttcctct acagtcaagg actttggcat gtggtggctg aaactgagct     3600

tttttgtgtg ggctccagtt ctcactgttc tgcaatgctc atggcaagtt gaatggtgag     3660

ctagcttata aattaaagag ctctgaactg tattcagacc gactgggtat ctagcttact     3720

gttttaacat cattgttgaa accagaccct gtagtccagt ggtgctgccc tgttgtgcaa     3780

actgctcctt tttctcgtgt ttttgtaaag agcttccatc tgggctggac ccagttcttg     3840

cacatacaag acaccgctgc agtcagctag gacctttccg ccatgtattc tattctgtag     3900

taaagcattt ccatcaacaa tgcctaattg tatctgttat ttttggttta acacacactg     3960

attcatacta ataaatattt tcagttttac cgttaaaaaa aaaaaaaaa                 4009


<210>  363
<211>  10740
<212>  DNA
<213>  homo sapiens

<400>  363
gtattggtgc agcccgccag ggtgtcactg gagacagaat ggaggtgctg ccggactcgg       60

aaatggggtc caagggtagc caaggatggc tgcagcttca tatgatcagt tgttaaagca      120

agttgaggca ctgaagatgg agaactcaaa tcttcgacaa gagctagaag ataattccaa      180

tcatcttaca aaactggaaa ctgaggcatc taatatgaag gaagtactta aacaactaca      240

aggaagtatt gaagatgaag ctatggcttc ttctggacag attgatttat tagagcgtct      300

taaagagctt aacttagata gcagtaattt ccctggagta aaactgcggt caaaaatgtc      360

cctccgttct tatggaagcc gggaaggatc tgtatcaagc cgttctggag agtgcagtcc      420

tgttcctatg ggttcatttc caagaagagg gtttgtaaat ggaagcagag aaagtactgg      480

atatttagaa gaacttgaga aagagaggtc attgcttctt gctgatcttg acaaagaaga      540

aaaggaaaaa gactggtatt acgctcaact tcagaatctc actaaaagaa tagatagtct      600

tcctttaact gaaaattttt ccttacaaac agatatgacc agaaggcaat tggaatatga      660

agcaaggcaa atcagagttg cgatggaaga acaactaggt acctgccagg atatggaaaa      720

acgagcacag cgaagaatag ccagaattca gcaaatcgaa aaggacatac ttcgtatacg      780

acagctttta cagtcccaag caacagaagc agagaggtca tctcagaaca agcatgaaac      840

cggctcacat gatgctgagc ggcagaatga aggtcaagga gtgggagaaa tcaacatggc      900

aacttctggt aatggtcagg gttcaactac acgaatggac catgaaacag ccagtgtttt      960

gagttctagt agcacacact ctgcacctcg aaggctgaca agtcatctgg gaaccaaggt     1020

ggaaatggtg tattcattgt tgtcaatgct tggtactcat gataaggatg atatgtcgcg     1080

aactttgcta gctatgtcta gctcccaaga cagctgtata tccatgcgac agtctggatg     1140

tcttcctctc ctcatccagc ttttacatgg caatgacaaa gactctgtat tgttgggaaa     1200

ttcccggggc agtaaagagg ctcgggccag ggccagtgca gcactccaca acatcattca     1260

ctcacagcct gatgacaaga gaggcaggcg tgaaatccga gtccttcatc ttttggaaca     1320

gatacgcgct tactgtgaaa cctgttggga gtggcaggaa gctcatgaac caggcatgga     1380

ccaggacaaa aatccaatgc cagctcctgt tgaacatcag atctgtcctg ctgtgtgtgt     1440

tctaatgaaa ctttcatttg atgaagagca tagacatgca atgaatgaac tagggggact     1500

acaggccatt gcagaattat tgcaagtgga ctgtgaaatg tatgggctta ctaatgacca     1560

ctacagtatt acactaagac gatatgctgg aatggctttg acaaacttga cttttggaga     1620

tgtagccaac aaggctacgc tatgctctat gaaaggctgc atgagagcac ttgtggccca     1680

actaaaatct gaaagtgaag acttacagca ggttattgcg agtgttttga ggaatttgtc     1740

ttggcgagca gatgtaaata gtaaaaagac gttgcgagaa gttggaagtg tgaaagcatt     1800

gatggaatgt gctttagaag ttaaaaagga atcaaccctc aaaagcgtat tgagtgcctt     1860

atggaatttg tcagcacatt gcactgagaa taaagctgat atatgtgctg tagatggtgc     1920

acttgcattt ttggttggca ctcttactta ccggagccag acaaacactt tagccattat     1980

tgaaagtgga ggtgggatat tacggaatgt gtccagcttg atagctacaa atgaggacca     2040

caggcaaatc ctaagagaga acaactgtct acaaacttta ttacaacact taaaatctca     2100

tagtttgaca atagtcagta atgcatgtgg aactttgtgg aatctctcag caagaaatcc     2160

taaagaccag gaagcattat gggacatggg ggcagttagc atgctcaaga acctcattca     2220

ttcaaagcac aaaatgattg ctatgggaag tgctgcagct ttaaggaatc tcatggcaaa     2280

taggcctgcg aagtacaagg atgccaatat tatgtctcct ggctcaagct tgccatctct     2340

tcatgttagg aaacaaaaag ccctagaagc agaattagat gctcagcact tatcagaaac     2400

ttttgacaat atagacaatt taagtcccaa ggcatctcat cgtagtaagc agagacacaa     2460

gcaaagtctc tatggtgatt atgtttttga caccaatcga catgatgata ataggtcaga     2520

caattttaat actggcaaca tgactgtcct ttcaccatat ttgaatacta cagtgttacc     2580

cagctcctct tcatcaagag gaagcttaga tagttctcgt tctgaaaaag atagaagttt     2640

ggagagagaa cgcggaattg gtctaggcaa ctaccatcca gcaacagaaa atccaggaac     2700

ttcttcaaag cgaggtttgc agatctccac cactgcagcc cagattgcca aagtcatgga     2760

agaagtgtca gccattcata cctctcagga agacagaagt tctgggtcta ccactgaatt     2820

acattgtgtg acagatgaga gaaatgcact tagaagaagc tctgctgccc atacacattc     2880

aaacacttac aatttcacta agtcggaaaa ttcaaatagg acatgttcta tgccttatgc     2940

caaattagaa tacaagagat cttcaaatga tagtttaaat agtgtcagta gtagtgatgg     3000

ttatggtaaa agaggtcaaa tgaaaccctc gattgaatcc tattctgaag atgatgaaag     3060

taagttttgc agttatggtc aatacccagc cgacctagcc cataaaatac atagtgcaaa     3120

tcatatggat gataatgatg gagaactaga tacaccaata aattatagtc ttaaatattc     3180

agatgagcag ttgaactctg gaaggcaaag tccttcacag aatgaaagat gggcaagacc     3240

caaacacata atagaagatg aaataaaaca aagtgagcaa agacaatcaa ggaatcaaag     3300

tacaacttat cctgtttata ctgagagcac tgatgataaa cacctcaagt tccaaccaca     3360

ttttggacag caggaatgtg tttctccata caggtcacgg ggagccaatg gttcagaaac     3420

aaatcgagtg ggttctaatc atggaattaa tcaaaatgta agccagtctt tgtgtcaaga     3480

agatgactat gaagatgata agcctaccaa ttatagtgaa cgttactctg aagaagaaca     3540

gcatgaagaa gaagagagac caacaaatta tagcataaaa tataatgaag agaaacgtca     3600

tgtggatcag cctattgatt atagtttaaa atatgccaca gatattcctt catcacagaa     3660

acagtcattt tcattctcaa agagttcatc tggacaaagc agtaaaaccg aacatatgtc     3720

ttcaagcagt gagaatacgt ccacaccttc atctaatgcc aagaggcaga atcagctcca     3780

tccaagttct gcacagagta gaagtggtca gcctcaaaag gctgccactt gcaaagtttc     3840

ttctattaac caagaaacaa tacagactta ttgtgtagaa gatactccaa tatgtttttc     3900

aagatgtagt tcattatcat ctttgtcatc agctgaagat gaaataggat gtaatcagac     3960

gacacaggaa gcagattctg ctaataccct gcaaatagca gaaataaaag aaaagattgg     4020

aactaggtca gctgaagatc ctgtgagcga agttccagca gtgtcacagc accctagaac     4080

caaatccagc agactgcagg gttctagttt atcttcagaa tcagccaggc acaaagctgt     4140

tgaattttct tcaggagcga aatctccctc caaaagtggt gctcagacac ccaaaagtcc     4200

acctgaacac tatgttcagg agaccccact catgtttagc agatgtactt ctgtcagttc     4260

acttgatagt tttgagagtc gttcgattgc cagctccgtt cagagtgaac catgcagtgg     4320

aatggtaagt ggcattataa gccccagtga tcttccagat agccctggac aaaccatgcc     4380

accaagcaga agtaaaacac ctccaccacc tcctcaaaca gctcaaacca agcgagaagt     4440

acctaaaaat aaagcaccta ctgctgaaaa gagagagagt ggacctaagc aagctgcagt     4500

aaatgctgca gttcagaggg tccaggttct tccagatgct gatactttat tacattttgc     4560

cacggaaagt actccagatg gattttcttg ttcatccagc ctgagtgctc tgagcctcga     4620

tgagccattt atacagaaag atgtggaatt aagaataatg cctccagttc aggaaaatga     4680

caatgggaat gaaacagaat cagagcagcc taaagaatca aatgaaaacc aagagaaaga     4740

ggcagaaaaa actattgatt ctgaaaagga cctattagat gattcagatg atgatgatat     4800

tgaaatacta gaagaatgta ttatttctgc catgccaaca aagtcatcac gtaaagcaaa     4860

aaagccagcc cagactgctt caaaattacc tccacctgtg gcaaggaaac caagtcagct     4920

gcctgtgtac aaacttctac catcacaaaa caggttgcaa ccccaaaagc atgttagttt     4980

tacaccgggg gatgatatgc cacgggtgta ttgtgttgaa gggacaccta taaacttttc     5040

cacagctaca tctctaagtg atctaacaat cgaatcccct ccaaatgagt tagctgctgg     5100

agaaggagtt agaggagggg cacagtcagg tgaatttgaa aaacgagata ccattcctac     5160

agaaggcaga agtacagatg aggctcaagg aggaaaaacc tcatctgtaa ccatacctga     5220

attggatgac aataaagcag aggaaggtga tattcttgca gaatgcatta attctgctat     5280

gcccaaaggg aaaagtcaca agcctttccg tgtgaaaaag ataatggacc aggtccagca     5340

agcatctgcg tcttcttctg cacccaacaa aaatcagtta gatggtaaga aaaagaaacc     5400

aacttcacca gtaaaaccta taccacaaaa tactgaatat aggacacgtg taagaaaaaa     5460

tgcagactca aaaaataatt taaatgctga gagagttttc tcagacaaca aagattcaaa     5520

gaaacagaat ttgaaaaata attccaaggt cttcaatgat aagctcccaa ataatgaaga     5580

tagagtcaga ggaagttttg cttttgattc acctcatcat tacacgccta ttgaaggaac     5640

tccttactgt ttttcacgaa atgattcttt gagttctcta gattttgatg atgatgatgt     5700

tgacctttcc agggaaaagg ctgaattaag aaaggcaaaa gaaaataagg aatcagaggc     5760

taaagttacc agccacacag aactaacctc caaccaacaa tcagctaata agacacaagc     5820

tattgcaaag cagccaataa atcgaggtca gcctaaaccc atacttcaga aacaatccac     5880

ttttccccag tcatccaaag acataccaga cagaggggca gcaactgatg aaaagttaca     5940

gaattttgct attgaaaata ctccggtttg cttttctcat aattcctctc tgagttctct     6000

cagtgacatt gaccaagaaa acaacaataa agaaaatgaa cctatcaaag agactgagcc     6060

ccctgactca cagggagaac caagtaaacc tcaagcatca ggctatgctc ctaaatcatt     6120

tcatgttgaa gataccccag tttgtttctc aagaaacagt tctctcagtt ctcttagtat     6180

tgactctgaa gatgacctgt tgcaggaatg tataagctcc gcaatgccaa aaaagaaaaa     6240

gccttcaaga ctcaagggtg ataatgaaaa acatagtccc agaaatatgg gtggcatatt     6300

aggtgaagat ctgacacttg atttgaaaga tatacagaga ccagattcag aacatggtct     6360

atcccctgat tcagaaaatt ttgattggaa agctattcag gaaggtgcaa attccatagt     6420

aagtagttta catcaagctg ctgctgctgc atgtttatct agacaagctt cgtctgattc     6480

agattccatc ctttccctga aatcaggaat ctctctggga tcaccatttc atcttacacc     6540

tgatcaagaa gaaaaaccct ttacaagtaa taaaggccca cgaattctaa aaccagggga     6600

gaaaagtaca ttggaaacta aaaagataga atctgaaagt aaaggaatca aaggaggaaa     6660

aaaagtttat aaaagtttga ttactggaaa agttcgatct aattcagaaa tttcaggcca     6720

aatgaaacag ccccttcaag caaacatgcc ttcaatctct cgaggcagga caatgattca     6780

tattccagga gttcgaaata gctcctcaag tacaagtcct gtttctaaaa aaggcccacc     6840

ccttaagact ccagcctcca aaagccctag tgaaggtcaa acagccacca cttctcctag     6900

aggagccaag ccatctgtga aatcagaatt aagccctgtt gccaggcaga catcccaaat     6960

aggtgggtca agtaaagcac cttctagatc aggatctaga gattcgaccc cttcaagacc     7020

tgcccagcaa ccattaagta gacctataca gtctcctggc cgaaactcaa tttcccctgg     7080

tagaaatgga ataagtcctc ctaacaaatt atctcaactt ccaaggacat catcccctag     7140

tactgcttca actaagtcct caggttctgg aaaaatgtca tatacatctc caggtagaca     7200

gatgagccaa cagaacctta ccaaacaaac aggtttatcc aagaatgcca gtagtattcc     7260

aagaagtgag tctgcctcca aaggactaaa tcagatgaat aatggtaatg gagccaataa     7320

aaaggtagaa ctttctagaa tgtcttcaac taaatcaagt ggaagtgaat ctgatagatc     7380

agaaagacct gtattagtac gccagtcaac tttcatcaaa gaagctccaa gcccaacctt     7440

aagaagaaaa ttggaggaat ctgcttcatt tgaatctctt tctccatcat ctagaccagc     7500

ttctcccact aggtcccagg cacaaactcc agttttaagt ccttcccttc ctgatatgtc     7560

tctatccaca cattcgtctg ttcaggctgg tggatggcga aaactcccac ctaatctcag     7620

tcccactata gagtataatg atggaagacc agcaaagcgc catgatattg cacggtctca     7680

ttctgaaagt ccttctagac ttccaatcaa taggtcagga acctggaaac gtgagcacag     7740

caaacattca tcatcccttc ctcgagtaag cacttggaga agaactggaa gttcatcttc     7800

aattctttct gcttcatcag aatccagtga aaaagcaaaa agtgaggatg aaaaacatgt     7860

gaactctatt tcaggaacca aacaaagtaa agaaaaccaa gtatccgcaa aaggaacatg     7920

gagaaaaata aaagaaaatg aattttctcc cacaaatagt acttctcaga ccgtttcctc     7980

aggtgctaca aatggtgctg aatcaaagac tctaatttat caaatggcac ctgctgtttc     8040

taaaacagag gatgtttggg tgagaattga ggactgtccc attaacaatc ctagatctgg     8100

aagatctccc acaggtaata ctcccccggt gattgacagt gtttcagaaa aggcaaatcc     8160

aaacattaaa gattcaaaag ataatcaggc aaaacaaaat gtgggtaatg gcagtgttcc     8220

catgcgtacc gtgggtttgg aaaatcgcct gaactccttt attcaggtgg atgcccctga     8280

ccaaaaagga actgagataa aaccaggaca aaataatcct gtccctgtat cagagactaa     8340

tgaaagttct atagtggaac gtaccccatt cagttctagc agctcaagca aacacagttc     8400

acctagtggg actgttgctg ccagagtgac tccttttaat tacaacccaa gccctaggaa     8460

aagcagcgca gatagcactt cagctcggcc atctcagatc ccaactccag tgaataacaa     8520

cacaaagaag cgagattcca aaactgacag cacagaatcc agtggaaccc aaagtcctaa     8580

gcgccattct gggtcttacc ttgtgacatc tgtttaaaag agaggaagaa tgaaactaag     8640

aaaattctat gttaattaca actgctatat agacattttg tttcaaatga aactttaaaa     8700

gactgaaaaa ttttgtaaat aggtttgatt cttgttagag ggtttttgtt ctggaagcca     8760

tatttgatag tatactttgt cttcactggt cttattttgg gaggcactct tgatggttag     8820

gaaaaaaata gtaaagccaa gtatgtttgt acagtatgtt ttacatgtat ttaaagtagc     8880

atcccatccc aacttccttt aattattgct tgtcttaaaa taatgaacac tacagataga     8940

aaatatgata tattgctgtt atcaatcatt tctagattat aaactgacta aacttacatc     9000

agggaaaaat tggtatttat gcaaaaaaaa atgtttttgt ccttgtgagt ccatctaaca     9060

tcataattaa tcatgtggct gtgaaattca cagtaatatg gttcccgatg aacaagttta     9120

cccagcctgc tttgctttac tgcatgaatg aaactgatgg ttcaatttca gaagtaatga     9180

ttaacagtta tgtggtcaca tgatgtgcat agagatagct acagtgtaat aatttacact     9240

attttgtgct ccaaacaaaa caaaaatctg tgtaactgta aaacattgaa tgaaactatt     9300

ttacctgaac tagattttat ctgaaagtag gtagaatttt tgctatgctg taatttgttg     9360

tatattctgg tatttgaggt gagatggctg ctcttttatt aatgagacat gaattgtgtc     9420

tcaacagaaa ctaaatgaac atttcagaat aaattattgc tgtatgtaaa ctgttactga     9480

aattggtatt tgtttgaagg gtcttgtttc acatttgtat taataattgt ttaaaatgcc     9540

tcttttaaaa gcttatataa atttttttct tcagcttcta tgcattaaga gtaaaattcc     9600

tcttactgta ataaaaacaa ttgaagaaga ctgttgccac ttaaccattc catgcgttgg     9660

cacttatcta ttcctgaaat ttcttttatg tgattagctc atcttgattt ttaatatttt     9720

tccacttaaa cttttttttc ttactccact ggagctcagt aaaagtaaat tcatgtaata     9780

gcaatgcaag cagcctagca cagactaagc attgagcata ataggcccac ataatttcct     9840

ctttcttaat attatagaat tctgtacttg aaattgattc ttagacattg cagtctcttc     9900

gaggctttac agtgtaaact gtcttgcccc ttcatcttct tgttgcaact gggtctgaca     9960

tgaacacttt ttatcaccct gtatgttagg gcaagatctc agcagtgaag tataatcagc    10020

actttgccat gctcagaaaa ttcaaatcac atggaacttt agaggtagat ttaatacgat    10080

taagatattc agaagtatat tttagaatcc ctgcctgtta aggaaacttt atttgtggta    10140

ggtacagttc tggggtacat gttaagtgtc cccttataca gtggagggaa gtcttccttc    10200

ctgaaggaaa ataaactgac acttattaac taagataatt tacttaatat atcttccctg    10260

atttgtttta aaagatcaga gggtgactga tgatacatgc atacatattt gttgaataaa    10320

tgaaaattta tttttagtga taagattcat acactctgta tttggggagg gaaaaccttt    10380

ttaagcatgg tggggcactc agataggagt gaatacacct acctggtgcc ttgaaaatca    10440

catcaagtag ttaattatct accccttacc tgtgtttata acttccaggt aatgagaatg    10500

atttttttta aagctaaaat gccagtaaat aaaagtgcta tgacttgagc taagatattt    10560

gactccaatg cctgtactgt gtctactgca ccactttgta aacacttcaa tttactatct    10620

ttgaaatgat tgacctttaa atttttgcca aatgttatct gaaattgtct atgaatacca    10680

tctacttctg ttgttttccc aggcttccat aaacaatgga gatacatgca aaaaaaaaaa    10740


<210>  364
<211>  3844
<212>  DNA
<213>  homo sapiens

<400>  364
gtctttacgt agacgtcggg ggcgcagccg cgctgtgcgc ggtgactggc ggctgcactg       60

gcggcagctg gaggtgtaat agtgcgggta gtgggtttgg agaagttccg aggcggcggt      120

ggcgccggtc aggacaagga tagcggaacc gggccctggg cttgtcgctc accatgccga      180

cagtagagga gctttaccgc aattatggca tcctggccga tgccacggag caagtgggcc      240

agactcatcc atctccccca actcaaaaat gaaacaaaga tggagggaga acggaattgg      300

gaagcataaa gatgcctatc aagtgatatt ggatggtgtg aaaggtggta ctaaggaaaa      360

gcgattagca gctcaattta ttccgaaatt ctttaagcat tttccagaat tggctgattc      420

tgctatcaat gcacagttag acctctgtga ggatgaagat gtatctattc gacgtcaagc      480

aattaaagaa ctgcctcaat ttgccactgg agaaaatctt cctcgagtgg cagatatact      540

aacgcaactt ttgcagacag atgactctgc agaatttaac ctagtgaaca atgccctatt      600

aagtatattt aaaatggatg caaaagggac tttaggtggg ttgttcagcc aaatacttca      660

aggagaggac attgttagag aacgagcaat taaattcctt tctacaaaac ttaagacttt      720

accagatgaa gtcttaacaa aggaagtgga agagcttata ctaactgaat ccaaaaaggt      780

cctagaagat gtgactggtg aagaatttgt tctatttatg aagatactgt ctgggttaaa      840

aagcttacag acagtgagtg gaagacagca acttgtagag ttggtggctg aacaggccga      900

cctagaacag accttcaatc cctcggatcc tgactgtgtg gacaggctct tacagtgcac      960

tcggcaggca gtacccctct tctctaaaaa tgtccattcc acaaggtttg tgacatattt     1020

ctgtgagcag gttctcccta acctcggtac cttgactacc ccagtggaag gtcttgatat     1080

acagttggag gtattgaaat tgttggcgga gatgagttca ttttgtggtg acatggaaaa     1140

actagaaaca aatttaagga aactatttga taagttattg gaatacatgc ccctccctcc     1200

agaagaggca gaaaatggag agaatgctgg taatgaagaa cccaagctac agttcagtta     1260

tgtggaatgt ttgttgtaca gttttcacca gttgggccga aaacttccag atttcttaac     1320

agccaaactg aatgcagaaa agctcaaaga tttcaaaatc aggctgcagt actttgcacg     1380

gggcctgcaa gtttatatca gacaacttcg cttagctctc cagggtaaaa cgggtgaggc     1440

cttaaaaaca gaagagaaca agattaaagt cgttgcattg aaaataacaa acaatatcaa     1500

tgttttaatc aaggatctct tccacattcc tccttcttat aagagcacag taacactatc     1560

ctggaaacct gtacaaaagg ttgagattgg gcaaaagaga gccagtgaag atacaacttc     1620

aggttcacca cccaagaaat cttcagcagg accaaaaaga gatgccaggc agatttataa     1680

ccctcccagt gggaaatata gcagcaattt gggcaacttt aattatgagc agagaggagc     1740

cttcagggga agtagaggtg gccgaggttg gggcacacga ggaaatcgta gtcggggaag     1800

actctactga ataagacatc agcattcttc agcattgtca tgagcttaat atacttaaat     1860

tctactactc attggattgc cggggatgtc cctttaaaca gactgctgcc ttcagctaaa     1920

aacttaatgt tctttatacc tttgtatgta tgacctactt ttgtaacaga ccatggttgt     1980

gtccaaggta aaaccacagt gatatttttg gatgctttgt ctgcaatctt gacttgtttt     2040

tgcagtatca ttattcagac ttcaaattgt gaatctttta aacatcttga taatttgttg     2100

ttgagagctg ttcattctaa aatgtaatga aattcagtct agttctgctg ataaagatca     2160

tcagttttga aaggttactg attttcctct tccctcttag ttttttaccc aatatatgga     2220

gaagagtaat ggtcaatctt aacattttgt tttaattgtt taataaagct gctgggcagt     2280

ggtgcagcat tcctacctag tgtcataaaa gcaaaatact tacatagctt tcttaaaata     2340

taggaatgac attacatttt taggagaaag taagttgctt tgcaccgcct acttaattct     2400

tttccatata ttgtgataca aacttttgaa tatggaatct tactatttga atagaaatgt     2460

gtatgtataa tatacataca tacataagca tatatgtgtg tgtgtgtgtg tatatatata     2520

tatatgcatg ctgtgaaact tgactacaca acataaatca ctttttaaat tccaggaacg     2580

ggtagtctga cacggtgatt atccttttga ggctgaatcc gttattaact tgttatttag     2640

gtttttactc ccagtagcaa gggattctaa gttagttgca cttacatgat tattgttatt     2700

taaaactaag aataaaggct gcattttcaa agataaattg gaattgctgt tggtgaaata     2760

acaaccaaaa tactgaatct gatgtacata caggtttcta caggaagaga tggtataatt     2820

tacaatttgg agatttaata accagggcta cccagaaaaa gtgacttgat aacatggtac     2880

caataagtaa gggatgctct ctcggtttgc ttttgccact ttcaagattt taacttctca     2940

ggttattaat caaaattatt gtataagtta gccaatagaa tttttaggtt aaaacaacag     3000

atggggggtt tgtggagtgt ttaatgtcat gggcattttt agtagcatag accctttgtt     3060

ctgcatttga atgtttcgta tatttttgtt tcacagttaa tcttccctcc ccaagtttgc     3120

tattcaaatc aactgcctga atgacatttc tagtagtctg atgtattttt ctgaggaata     3180

gtttgtgatt ccaatgcagg tgtcttcatt accattacct ctacactgca gaagaagcaa     3240

aactccttta ttagaattac tgcacatgtg tatggggaaa atagttctga aaggctagaa     3300

tgatacaagt gagcaaaagt tggtcagctt ggctatggag tggtggcaat aatctctaaa     3360

cattccaaaa gaccatgagc tgaacctaaa ctcccttgga atctgaacaa aggaatataa     3420

aattgccatt tgaaaactga ccagctaatc tggacctcag agatagatca gccagtggcc     3480

caaagccatt tcaagtacag aaattataga gactacagct aaataaattt gaacattaaa     3540

tataatttta ccactttttg tctttataag catatttgta aactcagaac tgagcagaag     3600

tgactttact ttctcaagtt tgatactgag ttgactgttc ccttatccct cacccttccc     3660

cttccctttc ctaaggcaat agtgcacaac ttaggttatt tttgcttccg aatttgaatg     3720

aaaaacttaa tgccatggat ttttttcttt tgcaagacac ctgtttatca tcttgtttaa     3780

atgtaaatgt ccccttatgc ttttgaaata aatttccttt tgtaattttg aaaaaaaaaa     3840

aaaa                                                                  3844


<210>  365
<211>  3908
<212>  DNA
<213>  homo sapiens

<400>  365
atcccagtgg gtggcagctg gaggcggggc accctgaggg gcggggaagg actagggtgc       60

ggggaggggg ttgcaaaagg agccgagcgg cttctgctca atggcggaaa agccgccggt      120

gctctgacgg cctcgttccc ctagcagttg cgggggagtt tcctgccggc gcggctggag      180

tctctgattc tcagggttcg gtggttggaa gatgctccag agagacgagg ctgcggcgga      240

ggaggtggcg gcggccgaat cggcaacggc gctagggtgg agagaaggcg gcatcggcgg      300

cggcggcggc gtgaggggcc gggcggtgta aacagccccg gaggcggcgg tcgagacccc      360

gagggggaag cggcggctga gtcagggtcg cgcctccgtt ggaaacttgg gctgagtacc      420

gcggcgggcg cgagcgaggc gccctagaca tcttctccct cccttgcctc agatttattg      480

ctaaacatgg gtgcattttt ggataaaccc aaaactgaaa aacataatgc tcatggtgct      540

gggaatggtt tacgttatgg cctgagcagc atgcaaggat ggagagtgga aatggaagat      600

gcacacacag ctgttgtagg tattcctcac ggcttggaag actggtcatt ttttgcagtt      660

tatgatggtc atgctggatc ccgagtggca aattactgct caacacattt attagaacac      720

atcactacta acgaagactt tagggcagct ggaaaatcag gatctgctct tgagctttca      780

gtggaaaatg ttaagaatgg tatcagaact ggatttttga aaattgatga atacatgcgt      840

aacttttcag acctcagaaa cgggatggac aggagtggtt caactgcagt gggagttatg      900

atttcaccta agcatatcta ctttatcaac tgtggtgatt cacgtgctgt tctgtatagg      960

aatggacaag tctgcttttc tacccaggat cacaaacctt gcaatccaag ggaaaaggag     1020

cgaatccaaa atgcaggagg cagcgtgatg atacaacgtg ttaatggttc attagcagta     1080

tctcgtgctc tgggggacta tgattacaag tgtgttgatg gcaagggccc aacagaacaa     1140

cttgtttctc cagagcctga ggtttatgaa attttaagag cagaagagga tgaatttatc     1200

atcttggctt gtgatgggat ctgggatgtt atgagtaatg aggagctctg tgaatatgtt     1260

aaatctaggc ttgaggtatc tgatgacctg gaaaatgtgt gcaattgggt agtggacact     1320

tgtttacaca agggaagtcg agataacatg agtattgtac tagtttgctt ttcaaatgct     1380

cccaaggtct cagatgaagc ggtgaaaaaa gattcagagt tggataagca cttggaatca     1440

cgggttgaag agattatgga gaagtctggc gaggaaggaa tgcctgatct tgcccatgtc     1500

atgcgcatct tgtctgcaga aaatatccca aatttgcctc ctgggggagg tcttgctggc     1560

aagcgtaatg ttattgaagc tgtttatagt agactgaatc cacatagaga aagtgatggg     1620

ggtgctggag atctagaaga cccatggtag ccttaaaaac cttctaaaat gcttttgatt     1680

ctgaaaattg ggggaaaaaa cttttaatca caattttctt caatacaagg ggaaaatatt     1740

cttgcggatt cccaacgttt tgtgatatga gcagaaaatc attagcattt cccatcattt     1800

gttcatattt gtgttttctg acagttgcca cttgtagcat tgcctgtact acagtatttt     1860

ttgccaacct caggcatact cgttacatct gtattgaact ttcggcccta gaaaccagtg     1920

gagttatttc accacaaatc aacaatgtgc ctgaggtgca tgggaaatat agttagctat     1980

actctgaaaa tacattatgt tttttttctt taaacaaaac acacaacatg taagcatgta     2040

agagtaaaga attgtatgat atgttccttt tttcagttca ccaagttgga agccttttgc     2100

agctctgtgg cttggaattt catttgagca atttctatag gatatgtatt tattattgat     2160

tgttatttaa tttttttcca attttacctg tattaccaaa ctgggttctc caataatgtc     2220

caaattgtaa tgttgccttg cttcaagata aagtgtattt gggaataata ttataaaccc     2280

ttacaaattt tatgcatgta tctactgcat ccttcaactc tcactagaaa atcttttgaa     2340

accaaatgga ttaatttatg gctatttata atttgctttg acatctcact gttggaaatt     2400

ttttaaagat gagatttgcc tttataatgt aaattgtgat ttttgtttta catgtgggtt     2460

tctatagttt taattttttc agcttttaag atacgagttt tgtgtaattt ggtattttta     2520

atcatttatg ttattttaaa agctcagaat atcacattga aattactata aatacattta     2580

aaattatcta ttttagatct aaggaaatac tacagagata ttttcatggg ttcagtaact     2640

tttcatttta taacattggg cacggtacag agtgattgtc acataaggta cttgaagatt     2700

tattagttta attctatttt tacagtaacc ttgaattctt ctgagttttg catgtattaa     2760

attcaattaa tgctgaacat gaagagtaaa gtatttatct gaaagaagtt tctgggttag     2820

gagaagtaat gaatgtatcc atttgtacat ggtttacatg ttgtggatgc tttgtaaaca     2880

ttttcctgta tgtttaaatt gtgtttcagc aggatgtaat tgcccttgtg tgtagttaaa     2940

atgagtcatc atctggtcct ttgtgaaatg gaattcatgg tattttctgt aacgttttcc     3000

tgaagctgtt tctggagagc cacacattta aatacagaca gctttcctga tcatttgatt     3060

tattgtgcac ctgatttttg gtctaaaagg aattattgcc acaatatatt ttatttattc     3120

tttagatttt agccttgtaa gttaaagtgc tttacatgat gatgtgaaaa gctgtttgtc     3180

cctttactgg gtttgggggg ttgttaaaag atagggaatg aagaatgcaa aatggtttat     3240

cgttcaaact gtccactctg atccaaccct gtactgatag tacttcccag tatgatattg     3300

tgatgtttca tacaatgcag tgaacataac caacttgtta cctaaataaa gaattgataa     3360

aaacagtgtg acatattact atttggtatg attcagtttt taatgttatt ttaaacttct     3420

tatatggttg gcatatttct gaaaatttaa ttccaaagag gaattaacca aactgtacag     3480

gacaatatta accccttctg tactctagaa atatttatac tccttttaaa aaaacctgcc     3540

tttggccggg tgcattggct cacacctgta atcccagcac tttgggaggc caaggcgggt     3600

ggatcacgag gtcaagagat cgtgaccatc ctggccaaca cggtgaaacc ctgcctctac     3660

taaaaataca aagattagct gggcatggtg gtgcttgcct gtaatcccag ctgcttggga     3720

ggctgaggca gaagaattgc ttgaacccag gaggcggagg ttgcagtgag ctaagatcgc     3780

gccactgcac tccagcctgg cgacagagcg agactccgtc tcaaaaaaaa aaaaaaagaa     3840

aaaaaaaaac ttttccggca gggggcaggg tgggggttac tggtgcttga aacagaaata     3900

atgtatga                                                              3908


<210>  366
<211>  2000
<212>  DNA
<213>  homo sapiens

<400>  366
agtcgctgag ccctggcgcc tccttaaagc cgcagctccg ccccgaccgc cccgcccgcc       60

agtccgtcct cagaccctcc caaccgccgg gtccccgccg cctcggcgga gtgttgtaga      120

gcctcgagcc tgcgaggagc gcgccgcccg ccagctccct gcgtcccgtc ccgcgtcccc      180

gcgttcccgc gtcctgcgat ccgccgccat ggccagtgag gagctggcgt gcaagctgga      240

gcgccggctg cggcgcgagg aggccgagga gagtggcccc cagctggctc ccctcggcgc      300

cccagccccg gagcccaagc ccgagcccga gcctcccgcc cgtgcgccca cggccagcgc      360

cgacgcggag ctgagcgccc agctgagccg gcggctggac atcaacgagg gcgctgcgcg      420

gccccggcgc tgcagggtct tcaaccccta cacggagttc ccggagttca gccgccgcct      480

catcaaggac ctggagagca tgttcaaact gtatgacgct gggcgggatg gcttcatcga      540

cctgatggag ctgaagctga tgatggagaa gctgggggcc ccccagaccc acctgggcct      600

gaagagcatg atcaaggagg tggatgagga cttcgatggc aagctcagct tccgggagtt      660

cctgctcatt ttccacaagg ccgcggcagg ggagctgcag gaggacagtg ggctgatggc      720

gctggcaaag ctttctgaga tcgatgtggc cctggagggt gtcaaaggtg ccaagaactt      780

ctttgaagcc aaggtccaag ccttgtcatc ggccagtaag tttgaagcag agttgaaagc      840

tgagcaagat gagcggaagc gggaggagga ggagaggcgg ctccgccagg cagccttcca      900

gaaactcaag gccaacttca atacatagtc ctgctgacct tgccctctgc ccacagctgt      960

gcctcacaga tgccccgaga agagatgact aggcatcttc atcactgctg tcggtcccct     1020

ccctgagcca gcatctccat ccaccacccc gtgccagctc ccgtgccagc cttcattcct     1080

cccagtgtcc aagcccctcc aggagggtcc tggggtgggc cagatgcctg cccacctctg     1140

tctcctgcct ctgctcctct gcccttctta tagccagaac ttgtatcttc tcagcaacct     1200

tcactttgtc cttgtccctt taccattccc catcaaagag tagtctgcta tatcaatttg     1260

tgtagatatg tctgtctttt tgggtcctca gagaaaatgc ccattttctc ggagaattct     1320

ctgcactcct ctctgcttca cattcaactt ccctgttctc atctttggta ggattctgcc     1380

agttgctttt gcatcttctg ttcctgggta atggtgggtc ttaatggagg ctgggtggac     1440

cactgcccgt ccactcttca acaggaggaa cagcatgcca ccatagtaac acacattaga     1500

gaaaggacag aggtctgctc cttcctgcca cctttctcct ggccccttag cattccccca     1560

gtccctccct cttcaccttg ctccgtctat gtcttcccag ctcagccttt tccccactct     1620

taaatactgt actacttcac tgtaagaacg aaagaatagt taggatacca atgagtaaaa     1680

gggttcctgt tcactctgac tctgtgcaaa ttgtattaca gtagaccgct gacgttccca     1740

agtgacagat ccagggcctt tcaaacatcc ccaaagtcat ggccatactc accattagcc     1800

agtttctaac atctgtttca gggtatccag ctgtagatgt tcttatcccc catacttgtg     1860

agttcttggg gttgctcaca aatactaggg gtttttgttg tatttttaac aaatatatcc     1920

taatgtcata tttattctct tttgtaactg ctgtctttac aataaagaaa tcatctgcct     1980

ttctatctta aaaaaaaaaa                                                 2000


<210>  367
<211>  9953
<212>  DNA
<213>  homo sapiens

<400>  367
gacctagcgt gtgctcagct ctggacaaga catggatgta ggcagacatg cttcctgcct       60

gctgggctta gtgcaccaat gctaaggaca gacatgaagg gcttgggaaa ggcatgaaga      120

tgcagggagt ctaggagaga ggataagaaa aacaagcatt ttgtggtggg ttgaattgcg      180

ttgtcgtttt tagaggcatt tcgtgatcca tggttgcgct cccgtgaaga gcgagtctag      240

agaaggaatc cgaagcggcg gcggcgagcg cggctcaggt tgatttagaa tacgggtgac      300

agtggcctgg cgcgagccca ctgctgacga aagcggctta tcccgcgcgg tttccatgga      360

gacgagccgg agccgcggcg gcggcggggc tgtcagcgag cgcggcggag ctggcgcgtc      420

cgtgggggtc tgcaggagga aggcggaggc cggggccggg accgggaccc tcgcggcaga      480

catggacttg cattgtgact gtgccgccga aacgccggcc gccgagccgc cgtcggggaa      540

gattaataaa gctgccttca aattattcaa gaagaggaaa tcgggtggca ccatgcccag      600

catttttggg gtcaaaaaca aaggggacgg gaaaagctcg ggtccgacgg ggctggtgag      660

gagcaggacc cacgacggac ttgccgaggt gctggtgctg gagagcggca ggaaggagga      720

gccgcgcggc gggggcgaca gcggcggggg cggcgggggg cggccgaacc cggggccccc      780

cagagccgca gggcccggcg ggggctccct cgccagcagc tcggtggcca agtcgcacag      840

cttcttctcg ctgctgaaga agaacgggcg ctcggaaaac ggcaagggag agcctgtgga      900

cgcgagcaag gccggcggca aacaaaagcg ggggctgcgg gggctgttca gcggcatgcg      960

ctggcacagg aaagacaagc gggccaaggc ggaggccgcg gaggggcgcg cgcccggggg     1020

cggcttgatc ctacccggct cgctcaccgc cagcctggag tgcgtcaagg aggagacgcc     1080

cagagccgcg cgcgagccgg aggagcccag ccaggacgcc ccgcgagacc cagcaggctg     1140

tggagatatt attgcagacc aagaggaaga ggcaggtccc agctgtgaca agcatgtccc     1200

cgggccaggc aagccggctc tgtctaaaaa gaaccccggc gtggtggcct accaaggagg     1260

cggggaagag atggccagcc cggacgaggt ggacgacacc tatctacagg agttctggga     1320

catgctctcc cagaccgagg agcagggacc cgagccccag gagggcgcgg ctaaggtggc     1380

agctgcgctg gaaaccaagg tggtgcccga gacccccaaa gacaccaggt gtgtggaagc     1440

ggccaaggac gcgtcctcgg tcaagcgcag gaggctcaac cggattccca tcgagcccca     1500

tcctaaggag gagcccaagc acccggagaa ggagcagcag gaaggcgtcc ccaacagcga     1560

cgagggctac tgggactcca ccacgccagg cccagaggaa gacagctcga gcagcgggaa     1620

gaaggcgggc atcccccggg atagctacag cggggacgcg ctctatgatc tctatgctga     1680

cccggacgga agtccagcaa cccttcctgg agggaaggac aacgaggaga cgtcctccct     1740

gtcccggtta aagcccgtat ctccaggcac catcacctgt ccactgcgaa caccaggcag     1800

cttgctgaag gactctaaga tccctattag catcaagcac ctgaccaacc ttccatctag     1860

ccatcccgtg gtgcaccagc aaccctccag gagtgagatg cccagaacaa aaatcccggt     1920

ttccaaagtg ctggtccgca gagtcagcaa ccggggcttg gctgggacca ccatcagagc     1980

aacggcctgc cacgacagtg ccaaaaagtt gtgaggtctt ccaggccaag gtggatgggc     2040

cccatgccaa ggaatacaac ttttccctgg aaaccactaa agtaagtttt gcttttccta     2100

aagaaagtct tttaggacac cacccgtccc ccgccctgct ccagagcgtg gaccgaggag     2160

gtctttgtgc cctgagcagg gaccggataa caccagaaag agggatgcta cacgggggtt     2220

tctcctctca agataagtcc ctgagaatta ttttcaagca cttttttctt ttttaccttt     2280

aagtttttct tccttttgct ttaatatact gaacacttgg aagtcacctt tacttgcctt     2340

tgcagaaaac agaacttagc caaacctaag taagagtcat gcctggatat tgggataagc     2400

cagtgtctag aggcctgaag gaaccgctga agaaccagag gagatctcct cttccaagac     2460

acgtttcctt ccttcccttc tttcctcttt cctttccagt taaaaaaaaa caaaaacaaa     2520

aacaaaaccc tttgctgtat cactgtgtgg aaaatacctc caaagctgaa agagccaggt     2580

atttacctga tgagcagagg ggaccactga ttggcagaaa acttccctac gttcagttgt     2640

tagatatgca aattgataag gatctaacac taggaaaata aaggcgagtt ttggtttggt     2700

tggtttcagt catttgtttg gggagatata aaaggctcag gagagcaggc ttttgctttt     2760

gcttttgttt gtttcttccc ccacccagtg cagaaatcag gatcagggaa agattttatt     2820

aaatgccaat agatacagta tttaagcatt tataaactga aaccttttca tgtgaagata     2880

atgcatattt taccgtttat ccagctgtta acattttgta atcagtcaat tcaatagaat     2940

tattctggat aattctatat ctagaatata aaatctggtc ttatagctag acatgatgat     3000

ggtccccaaa ccattgatgt tctgttatgt actgtaatgg gaagcgattc tgattttgtt     3060

ttatatgggt tctctggttc tcaaaaaaaa aaaaaatcta ttgtgctggt gtcccagagg     3120

aatggctctg ccttgttttg ggtaagagtc tgtttctcac cccaaaccct gttttcagat     3180

ttttttttac cttgattgta aaatttcaga tccaaccatt cctcaatata atgagtgcaa     3240

aatgaggaac acataaagaa aaacaataga aagatacagt ttttcacatc atttgccttt     3300

tgctttatag acttatgaca aagacaagtg tgttcagaat atgacactgg caagcttatg     3360

tattgtaaac actttatgcc aagttttttt tgaaaagtgg tttgcttcta tgtatgtttt     3420

ctaatatttc agatgaaaca tttatttcag aaagggttat tatatgccta gtttgaatga     3480

taaactgaag cagttcctag aatgctatta gtgtctaatg atgaaattaa tatccttttt     3540

gaaatacact tcagtgtatt taatcaaaag accagagctt ctactaggag gtgattcatc     3600

ataccaggaa gattatgcat attcacgtga aactgcacat atgtaaatga catgaacact     3660

tctgtataag tctcatttcc agagagattg cattagtaat gaactgttat tacatgcttt     3720

ttaagtttgt tttctgtttc ataaatgaaa gaacaaggca agttaaatat atgaaaacct     3780

attttaataa tatgaagaaa gtaacaaaat aaatggacat caaaggaaag caaattgagc     3840

cagtagcaga aagtaggcca ttccccattt taaatttgca gtgattcaat taggagaggt     3900

ttgctgaatt tcttcattag tcatatgact ggcttttatt gcattgtctc agatccataa     3960

tgttatttca aagtaatctt ttaatattta atttctttat gtgtgtaaat gaggccctat     4020

atgcagtcat agccttaagc attctgaaca cactaccaag aattcatata agcatctcac     4080

actcacgtgc tcatgcactc aactgtgtac agactaacag acaaaagaca tctactctag     4140

atctggaaat tatttttgaa attatttctg tattaaacaa gggatttaca tttgatttca     4200

tgccgctggt actatttagg ctcaaaatac attcatcttc ccctagtgaa tggagaaaat     4260

ataaatttta ttcctagctg taaaacaaag gatcttgatt tccttgttgt acattttcct     4320

gcaagggtta tattctcctt tgcatgaatc catggcaaag ttatgttggt tcatttgttc     4380

aattgtacag gaaagttaag aatacctgaa aaacttatga gaatattgta atagtaaagg     4440

caatctattt cttaagcagt agaagaaaag tttttgcttt cataatttta ggacttaatc     4500

ctccatttac accattatgc tgtgtctcct ctttataaga aaaggaacac gtgagcaaag     4560

tttatcttaa tttccactga cctgtcaatt aaccagttat aaaagatata aaatattttc     4620

ttttaaaatt tatattttcc actttttttt taccttattt tttaagaatt gcacccacac     4680

caatcaaata aaggatttgg gcaatgaatt aaacagcctc aatcacttga tgggaaatcc     4740

ctggagtggc aggaagagta gattctcaac tttttccaac catagaaaag ggatcatagt     4800

tgctttcttg tgccaagggc tactttctct catttgtgtt catggagatt gttttttcaa     4860

gaattttcct agatttacat tccaattttt attaatacat tatatctaat gaccttgtga     4920

agattattca ggcccatatt tgctgacttt ttaagggaag gattggatag aggctaatta     4980

tatctttccc acatgtatgt atattctaag atacttggtt gattgacttc ctttagttga     5040

aaggctgccc aaattagaca ggaaaaagtc aaatcaattg ttgggcgaaa atttatcggt     5100

tggtttaata gctctgcaca aagacagcct gacttgaatg tctatattac acatacactg     5160

ttatttgaaa cactctgctt tagtacagat ggtggttgat gcgtttatcc tgccattagc     5220

accaattggg agaaatttta ctacagcatt ttaaataatc acaagagtaa atagatttct     5280

attattttat ctaataacaa caatagaata tagaatacaa aggacttcct ctagatacat     5340

tttattttat ctaataacaa caatggaata tagaatacaa aggacttcct ttagatacat     5400

tttccacaaa ttatctgctt atttaaatac aaagggttta atatctatga aggtaataac     5460

tcaccgtgtt taaaggattt atttcttcat ctcagaggta gtcttcaagt atttgcagtt     5520

aaacagtatg caaatagccc tttgcttaca caattatcca ggtaaaaaga ctatgtcagg     5580

tgttgagatt tctttgaatt ttctaagagt tttcattatt tacgcctttg tcagattaat     5640

tttaaaggca actcttgact gttagcttgg tgtgaagaga tccactcagg cagctcatgt     5700

ctcctaagtg ccctcagaca gcagtgacgg gacacttcac atgacgctag catgttggct     5760

ctgtccgcat ggcggaatgc attccctgct gttagttatc tgaatttttc tcctgaatta     5820

caaatatatg gatttggctc ccctgatgct gggcttctgc tgagacctgt tccagtacat     5880

tcacgtatgc tttgctcccc ttcattgtta agaaattaat tcaagaagtt ttttgctgtt     5940

aaacataagg aataagcatc acaattgcct catctcatca ctgaggaaag ctggtttaaa     6000

gtatctgagt gaaataagag gaaaacccca aatacttcac ctaacccagt ttccctttcc     6060

cctcctccag gcagagcaag gaaaagaaca gttgtaattt gtgtaaactc agccttagaa     6120

aatttcaatt cattacacac aaaaatattt atgaagcagt ttggaaccaa aggggtagta     6180

tggtagacga gtgtcttaca gagcctgtgt ggggaagcaa aaggcaaggg tgtagttcac     6240

aggcagaagc gagctgtgac attgtcagtg cagcgtgtaa gtgtggctcc tcacaggcgg     6300

ccattgattg tgagacctca tcttgctctg aagatttccc ggtggctgtc atgcattgct     6360

tctcaaaagc cttgcactgt gataaggttt aaggagacag attgttgcaa caatagccac     6420

ttctaaggaa tgttattatg tcactgcaga tgatgttttt aagaggtgat tcagaatgat     6480

agtttcgtga ttacggaaag gagttccttc tcaaactgca aaaggaaaga tgaaaatagt     6540

catgaagcct ccagaactga aattgggcac cttttatgat ggatatttac tttaattcaa     6600

tgcaacacat atttatgggg catagactgt atcaaatact taataaaacc cattcagttt     6660

ggagctcaca cctaagctgc gctgtaattg gattttctta atattcatta aaaacacaaa     6720

acaatattat tttacttttt tttggtattt gcatttgttg cttatagttt gtggggtgaa     6780

gcaaagtggt gtgaagttga agaagggcac tatgaattaa gccacacaaa tgcctctaaa     6840

aaatagtaaa tgtaacaatg gttaacattc attgaatact tactatgtgt caggcactgc     6900

taggagattt agaaataatt acttagtcct cttaacagcc atgtggggta ggtaatatta     6960

tctccccagt aagacagctt taattcatcc tttttgtttc tatccctttc catctctgtc     7020

tgtctgtctc tctctctctt ttcccctagt ctctaggaca gggatataaa ctctttagtg     7080

attttcagta atagagagct aagcactgct tagtgtcatt gtcagctcac ttctaataga     7140

aagagctaac ccatgtccac gcagctgaaa attagttttg tgtctgagat gatggtgctc     7200

acaatcatat acagggaacc ctgccactgt gctatgctga gtaggcaaac attggccttc     7260

ccttggaggg atcctcttct cttaggatta atgtgggaag tacagacaga aatctcttct     7320

gttgtcatgg cgatacttct tccctgacag ggtatcattc attcaaagca tatttgtttc     7380

atttgttttt attcctacct taagccatct tggtgggttc tgggtggtct atgcatatgt     7440

gtgtgtgttt taattgcagt aagaatattg aatatgagat ctaccctctt taattttttt     7500

tttttttttt tttgagatgg agtcttactc tgtcacccag gctggagtgc agtggcttga     7560

tctcggctca ctataacctc cacctcccag gttcaagtga ttctcctgcc tcagcctccc     7620

aagtagctga gactacaggc gtgcaccacc atgcccgtta gtttttgtat ttttagtaga     7680

gacagggttt caccatgttg gccaggctgg tctcaaactc ctgacctcaa atgatctgcc     7740

cacctctacc tccaaagtgt tgggattaca ggcaatgagc caccacgccc gggttacctt     7800

ctttaatttt taagtacaca atacagtatt gttaactata gccacagtgt tgtacagcaa     7860

atctctctca cctatgcatc ctgcgtaact gaaactctgt gcccattgaa cagcagctcc     7920

tcatttcctc ccccatcagc ccctggcagc catcattcta ctctctgctt ctgtgagtct     7980

ggctatttta gatcccttat agaagtggaa acgcgcagta tttgtccttc tgtgactggc     8040

ttatttcatt gagcataacg acccccaagt ttagccatgt tgttgcttat ggcaggattt     8100

ccttcttttt tcaggctgaa taatatttcc ttatatgtat atgctgcatt tttaaaaacc     8160

ctttcatcta ctgacagacg tttagattat ttccacatct tggctattat gagtaatgct     8220

acaacgaacg agggagtgaa aatatctctt taagatcctg atttcagttt ttttgaataa     8280

atacccagaa gtggaatgac tgggtcattc atatggtaat tctaattaaa catagaatta     8340

tttttaattt tttgagaaac ttctgtgctg ctttccacag tggttgcatc tgtttacata     8400

cttaccaatg gtgcacaagg gttccaattt ctccacatct ttgccaactt gttatctgtg     8460

tttgtttaaa tgacagctgt atgagttgtc ccttgcctcc atgcaattct gaacttcaga     8520

aataagcact tggctccttt aatagctgtc cgtcctatgt tgtgtctaca gccactgaat     8580

cctgtcctac attttctgat tcattaactc attcaactaa tagctattga acaccatcaa     8640

taagtcagcc accatgaaga tgagtatttt atattgaatt ctactaacat atcctgtatg     8700

tttactatgt tgccagagag gatgctgtgt gcttttttta cattgttatc tttactcttc     8760

acaagaacca tgtaaggtag gtattggtaa aatgggtaat tttggaaatg cttcaataat     8820

cgagtagaat aacttttgct ctatgtgaga agatacgttt taaataagat atggcttagg     8880

tttctggtta cctgagacat actatacctt ctcagatact ctcagacctg aatcatttaa     8940

caaactaagg cagaaatact aaaaatatct ggttcaataa cataggggca tggagtagac     9000

atgcagaaaa tgcttgttca cttgccttga aatggctcca ggtggcctga aggaatcaat     9060

gaaacttctc aagtatctac attacaacca ctggtcccca ctacacattt atttctaaat     9120

aaaggaggag aaactctagc aaagtaatat ttaacatttt cattgcttcc aggataaatc     9180

ttattgaata tggaggatct gatagtggta ggtctatcag gaatatcagg gaaaatgctt     9240

ttgatgttgt tggcaaagtc aattcctatc atttgtactt gacaccagct acctagcagg     9300

ctcattgtga acttcaggtt tcgcccacgt tatttatata aagtatctca gtgtaatata     9360

gggagttgct ggttatttga aaatagtaac aaaaataacc caaacgagaa actccatttc     9420

cataattagc tttcctgaaa gtcaggcatg tctttgagga caggttttgg cagtattatt     9480

tttgtgcaca ggaggaaaat tgttagtagg tttatagatg ttatttttat aatagaatgt     9540

taaacccctg aaaaacatca aaaattgtct cctagaacta attctatgtt ttaaaaactt     9600

gttttaaaaa ggattctaaa tagcaatagg gtctttcctc ctttctccac tccaatggtt     9660

taatgggata gaggaatcaa tgtttatatt tttaaacctg taaatatttt attttgggta     9720

ttttgtatat ttgttgatat aattccattt tgtgcatatg taccattgtg catgttgctg     9780

tttttgatag tcactctttt aatgaatgta agaagcttgg gctaatagca cttttcttgt     9840

tccattcaaa catctgaaaa tgaaattaca acactgccat tttactgttg tgtttaattc     9900

agtcaataaa ttttgttgct cctttgcatt taaagtgaaa aaaaaaaaaa aaa            9953


<210>  368
<211>  3352
<212>  DNA
<213>  homo sapiens

<400>  368
ggaatgttag cgggtgggag gtgcggctgg gttgctacag ccagagctgg gcggtggcgg       60

gcgctgctga aggagtctcg ctgagctcga ggaggtggcg cgatggaggg actggaagag      120

aatggaggtg ttgtccaagt tggagaattg ttaccttgca agatttgtgg aagaacattc      180

tttccagtag cattaaaaaa acatggaccc atttgccaga agactgcaac taaaaaacgg      240

aagacttttg attcaagcag acagagagct gaaggaactg atattccaac agtaaaacct      300

ctcaaaccga ggccagaacc accaaagaaa ccatctaatt ggagaaggaa acatgaagaa      360

ttcattgcta ccataagagc agctaaaggc cttgatcagg ccctcaaaga gggtggcaaa      420

cttcctcctc ctcctccacc ttcttatgat cctgattata ttcaatgtcc atattgtcag      480

aggagattca atgaaaatgc agctgataga catataaatt tctgtaaaga acaggcagca      540

cgtattagta ataaagggaa attttctaca gataccaaag gaaaaccaac ttctcggaca      600

caggtgtata agccacccgc acttaaaaag tcaaattctc ctggaactgc atcatcagga      660

tcttcacgat taccgcagcc aagtggcgct ggcaaaactg ttgtaggtgt tccttcaggt      720

aaagtgtctt caagtagcag ctctttggga aacaaacttc agaccttatc tccctctcat      780

aaagggatag cagcccctca tgcaggagct aatgtcaaac cccgaaattc cacaccacct      840

agtttggcaa gaaatcctgc cccaggtgtg cttacaaaca aaagaaaaac atatactgag      900

agctacatag ccaggccaga tggggactgt gcatcttccc ttaatggtgg aaatattaaa      960

ggcattgaag gacattcacc tggaaactta ccaaaattct gccatgagtg tgggactaaa     1020

taccctgtag aatgggccaa attttgctgt gaatgtggca ttcgaagaat gattctatga     1080

atagaatctc aaaaaaaaaa aaaagccaag ttcagagttt atgattattg ctgcttggac     1140

agctagagca catcctctag ttagtttgtg ctaaaaatac tcgaaatacc atttccagtt     1200

aattttgaag tgtaatcttt tggctatata atgtgtgtat gtttatatgt gtacatatac     1260

tgtatataat aaatatctga taccccagac tgtgtcattc aaggaaatat tcacttatct     1320

gtcagaaaat aatttcaaat ggaacaatta atttaggtgt tacttttctg ttgttgttaa     1380

agcacgttaa gtacatttcc acaaactctc atactctagt gcttagccct tcaagcttta     1440

ggataagtat aactttgagc aaaaaatttg gataaacatt tgtattattg gtgcctatct     1500

tcagatagta tcatagtagg atagatgctg ggaattttgt aattaaagag aacagtttta     1560

gttaccatta ggtatgttaa ggtcactcct gtagagcatg tcaacaaatt atttcataaa     1620

tccgaaaaac taagagaaaa aaaaacccct ctattagtta cgtaatttaa acatcttact     1680

tgttttgtaa aagtgtaatt atgcaatttc cttttcaaat acacaagact aaaaatacaa     1740

atctatcttg ttctatttat aactgatttt ttttagttct gtatgtattc gttgaacata     1800

tttttttact tccaattgtt tttccagatt tcacttttcc tctttttcca taacccgtga     1860

agatagtttt aatttgctag ttcatttttt gctgtatttg aaaatgtaat tatttaatat     1920

agaaggcaca gaattccctg caaaatctta catgtttaaa aacatataat tttttgtatc     1980

tgaatttaga ataaatcatt ttaatgcatc ttaaatcacg tcacctaatc ataatagttg     2040

tggtaactaa tcattagtgc agagcatgca gataaaaaat atttgaattt ttttttcttg     2100

gaagtacatg tagttatgag taggttaaga gaatatctaa ttttcctact ctttttttca     2160

tctttagcat ttaatgttga aacaccattc acgtcacatt aaggacccac tgaaaatgta     2220

ttgttttaat gcataattga cttacctaat taaacataca cacaaattta attatttttt     2280

tctctttaac ctgatcacga cacagctctt aatcattgtc actttcagta tatcatagta     2340

gttagtagta gattgccttg atggcagtaa ttctgtagta atttctattc aatcaaacct     2400

aagagagctt tgatcttact gtaaaggtac aaacaaatct cttatataat tcctagcttt     2460

tttttttgtt tatgattctg atcaactata agacacaatg taaagaattg tggcttataa     2520

tttatctgaa atttattagc ttagtttagt ttgggcagga gttacaaact taataggaat     2580

tgtcatttta cttacagttt atttcctgat tagttgttaa tttttttccc ctcagttatc     2640

tttattcagt cttattggtc aaaacaaaga aacaaatagt ccatcaacta aaataagctg     2700

taatgaattt agaagatgaa tgcatatatt agatttccat ttaaatcact tctgttataa     2760

atcatataaa gaactttaaa cttgttttat ctaatactga gcactgtttt tttgtcaagt     2820

atttttttaa gaccacataa ttctttttgt ctgctcaagg aaaggataga taaataattg     2880

gcacacattt gtttctcact gaattttaca gtagtaaatt aatgttataa tgtaccacat     2940

ggagatgagt tggtaagaaa tcatctagtt ccagagccca gagattataa acagtaggtg     3000

aaatagattt atgacttacg aaatatgttg tgacaatata tttaaatgca tttttatatt     3060

acttgcatat tctcacattg atttgtgcaa tagttcagtt ttaaaaaaaa tcttcctatg     3120

catcatgtat tttattttta tttattttca caagtatttg acagtatggt agaataaaag     3180

atgattgtaa gattaaaaat gtaaaaattg cttatgtatt attctgaatt gtgttaggtt     3240

gaaaaagatg attgtggtga ctattatttc ttgtccacta tttgtttttt gttttttcac     3300

caataatgtc ttcatatttg aacctattca ataaagacat gaagcataaa aa             3352


<210>  369
<211>  3352
<212>  DNA
<213>  homo sapiens

<400>  369
ggaatgttag cgggtgggag gtgcggctgg gttgctacag ccagagctgg gcggtggcgg       60

gcgctgctga aggagtctcg ctgagctcga ggaggtggcg cgatggaggg actggaagag      120

aatggaggtg ttgtccaagt tggagaattg ttaccttgca agatttgtgg aagaacattc      180

tttccagtag cattaaaaaa acatggaccc atttgccaga agactgcaac taaaaaacgg      240

aagacttttg attcaagcag acagagagct gaaggaactg atattccaac agtaaaacct      300

ctcaaaccga ggccagaacc accaaagaaa ccatctaatt ggagaaggaa acatgaagaa      360

ttcattgcta ccataagagc agctaaaggc cttgatcagg ccctcaaaga gggtggcaaa      420

cttcctcctc ctcctccacc ttcttatgat cctgattata ttcaatgtcc atattgtcag      480

aggagattca atgaaaatgc agctgataga catataaatt tctgtaaaga acaggcagca      540

cgtattagta ataaagggaa attttctaca gataccaaag gaaaaccaac ttctcggaca      600

caggtgtata agccacccgc acttaaaaag tcaaattctc ctggaactgc atcatcagga      660

tcttcacgat taccgcagcc aagtggcgct ggcaaaactg ttgtaggtgt tccttcaggt      720

aaagtgtctt caagtagcag ctctttggga aacaaacttc agaccttatc tccctctcat      780

aaagggatag cagcccctca tgcaggagct aatgtcaaac cccgaaattc cacaccacct      840

agtttggcaa gaaatcctgc cccaggtgtg cttacaaaca aaagaaaaac atatactgag      900

agctacatag ccaggccaga tggggactgt gcatcttccc ttaatggtgg aaatattaaa      960

ggcattgaag gacattcacc tggaaactta ccaaaattct gccatgagtg tgggactaaa     1020

taccctgtag aatgggccaa attttgctgt gaatgtggca ttcgaagaat gattctatga     1080

atagaatctc aaaaaaaaaa aaaagccaag ttcagagttt atgattattg ctgcttggac     1140

agctagagca catcctctag ttagtttgtg ctaaaaatac tcgaaatacc atttccagtt     1200

aattttgaag tgtaatcttt tggctatata atgtgtgtat gtttatatgt gtacatatac     1260

tgtatataat aaatatctga taccccagac tgtgtcattc aaggaaatat tcacttatct     1320

gtcagaaaat aatttcaaat ggaacaatta atttaggtgt tacttttctg ttgttgttaa     1380

agcacgttaa gtacatttcc acaaactctc atactctagt gcttagccct tcaagcttta     1440

ggataagtat aactttgagc aaaaaatttg gataaacatt tgtattattg gtgcctatct     1500

tcagatagta tcatagtagg atagatgctg ggaattttgt aattaaagag aacagtttta     1560

gttaccatta ggtatgttaa ggtcactcct gtagagcatg tcaacaaatt atttcataaa     1620

tccgaaaaac taagagaaaa aaaaacccct ctattagtta cgtaatttaa acatcttact     1680

tgttttgtaa aagtgtaatt atgcaatttc cttttcaaat acacaagact aaaaatacaa     1740

atctatcttg ttctatttat aactgatttt ttttagttct gtatgtattc gttgaacata     1800

tttttttact tccaattgtt tttccagatt tcacttttcc tctttttcca taacccgtga     1860

agatagtttt aatttgctag ttcatttttt gctgtatttg aaaatgtaat tatttaatat     1920

agaaggcaca gaattccctg caaaatctta catgtttaaa aacatataat tttttgtatc     1980

tgaatttaga ataaatcatt ttaatgcatc ttaaatcacg tcacctaatc ataatagttg     2040

tggtaactaa tcattagtgc agagcatgca gataaaaaat atttgaattt ttttttcttg     2100

gaagtacatg tagttatgag taggttaaga gaatatctaa ttttcctact ctttttttca     2160

tctttagcat ttaatgttga aacaccattc acgtcacatt aaggacccac tgaaaatgta     2220

ttgttttaat gcataattga cttacctaat taaacataca cacaaattta attatttttt     2280

tctctttaac ctgatcacga cacagctctt aatcattgtc actttcagta tatcatagta     2340

gttagtagta gattgccttg atggcagtaa ttctgtagta atttctattc aatcaaacct     2400

aagagagctt tgatcttact gtaaaggtac aaacaaatct cttatataat tcctagcttt     2460

tttttttgtt tatgattctg atcaactata agacacaatg taaagaattg tggcttataa     2520

tttatctgaa atttattagc ttagtttagt ttgggcagga gttacaaact taataggaat     2580

tgtcatttta cttacagttt atttcctgat tagttgttaa tttttttccc ctcagttatc     2640

tttattcagt cttattggtc aaaacaaaga aacaaatagt ccatcaacta aaataagctg     2700

taatgaattt agaagatgaa tgcatatatt agatttccat ttaaatcact tctgttataa     2760

atcatataaa gaactttaaa cttgttttat ctaatactga gcactgtttt tttgtcaagt     2820

atttttttaa gaccacataa ttctttttgt ctgctcaagg aaaggataga taaataattg     2880

gcacacattt gtttctcact gaattttaca gtagtaaatt aatgttataa tgtaccacat     2940

ggagatgagt tggtaagaaa tcatctagtt ccagagccca gagattataa acagtaggtg     3000

aaatagattt atgacttacg aaatatgttg tgacaatata tttaaatgca tttttatatt     3060

acttgcatat tctcacattg atttgtgcaa tagttcagtt ttaaaaaaaa tcttcctatg     3120

catcatgtat tttattttta tttattttca caagtatttg acagtatggt agaataaaag     3180

atgattgtaa gattaaaaat gtaaaaattg cttatgtatt attctgaatt gtgttaggtt     3240

gaaaaagatg attgtggtga ctattatttc ttgtccacta tttgtttttt gttttttcac     3300

caataatgtc ttcatatttg aacctattca ataaagacat gaagcataaa aa             3352


<210>  370
<211>  6256
<212>  DNA
<213>  homo sapiens

<400>  370
gcggccgccg cctccgcccc gcgttcgggg ccttcccgac cctgcactgc tgccgtccgc       60

ccgcccggcc gctcttctct tcgccgtggg agccgctccg ggcgcagggc cgcgcgccga      120

gccccgcagg ctgcagcgcc gcggcccggc ccggcgcccc ggcaacttcg ccgagagttg      180

aggcgaagtt tgggcgaccg cggcaggccc cggccgagct cccctctgcg cccccggcgt      240

cccgtcgagc ccagccccgc cgggggcgct cctcgccgcc cgcgcgccct ccccagccat      300

gtcgtccatc ctgcctttca ctcccccgat cgtgaagcgc ctgctgggct ggaagaaggg      360

cgagcagaac gggcaggagg agaaatggtg cgagaaggcg gtcaagagcc tggtcaagaa      420

actcaagaag acggggcagc tggacgagct ggagaaggcc atcaccacgc agaacgtcaa      480

caccaagtgc atcaccatcc ccaggtccct ggatggccgg ttgcaggtgt cccatcggaa      540

ggggctccct catgtcatct actgccgcct gtggcgatgg ccagacctgc acagccacca      600

cgagctacgg gccatggagc tgtgtgagtt cgccttcaat atgaagaagg acgaggtctg      660

cgtgaatccc taccactacc agagagtaga gacaccagtt ctacctcctg tgttggtgcc      720

acgccacaca gagatcccgg ccgagttccc cccactggac gactacagcc attccatccc      780

cgaaaacact aacttccccg caggcatcga gccccagagc aatattccag agaccccacc      840

ccctggctac ctgagtgaag atggagaaac cagtgaccac cagatgaacc acagcatgga      900

cgcaggttct ccaaacctat ccccgaatcc gatgtcccca gcacataata acttggacct      960

gcagccagtt acctactgcg agccggcctt ctggtgctcc atctcctact acgagctgaa     1020

ccagcgcgtc ggggagacat tccacgcctc gcagccatcc atgactgtgg atggcttcac     1080

cgacccctcc aattcggagc gcttctgcct agggctgctc tccaatgtca acaggaatgc     1140

agcagtggag ctgacacgga gacacatcgg aagaggcgtg cggctctact acatcggagg     1200

ggaggtcttc gcagagtgcc tcagtgacag cgctattttt gtccagtctc ccaactgtaa     1260

ccagcgctat ggctggcacc cggccaccgt ctgcaagatc ccaccaggat gcaacctgaa     1320

gatcttcaac aaccaggagt tcgctgccct cctggcccag tcggtcaacc agggctttga     1380

ggctgtctac cagttgaccc gaatgtgcac catccgcatg agcttcgtca aaggctgggg     1440

agcggagtac aggagacaga ctgtgaccag taccccctgc tggattgagc tgcacctgaa     1500

tgggcctttg cagtggcttg acaaggtcct cacccagatg ggctccccaa gcatccgctg     1560

ttccagtgtg tcttagagac atcaagtatg gtaggggagg gcaggcttgg ggaaaatggc     1620

catgcaggag gtggagaaaa ttggaactct actcaaccca ttgttgtcaa ggaagaagaa     1680

atctttctcc ctcaactgaa ggggtgcacc cacctgtttt ctgaaacaca cgagcaaacc     1740

cagaggtgga tgttatgaac agctgtgtct gccaaacaca tttacccttt ggccccactt     1800

tgaagggcaa gaaatggcgt ctgctctggt ggcttaagtg agcagaacag gtagtattac     1860

accaccggcc ccctcccccc agactctttt tttgagtgac agctttctgg gatgtcacag     1920

tccaaccaga aacacccctc tgtctaggac tgcagtgtgg agttcacctt ggaagggcgt     1980

tctaggtagg aagagcccgc agggccatgc agacctcatg cccagctctc tgacgcttgt     2040

gacagtgcct cttccagtga acattcccag cccagccccg ccccgccccg ccccaccact     2100

ccagcagacc ttgccccttg tgagctggat agacttggga tggggaggga gggagttttg     2160

tctgtctccc tcccctctca gaacatactg attgggaggt gcgtgttcag cagaacctgc     2220

acacaggaca gcgggaaaaa tcgatgagcg ccacctcttt aaaaactcac ttacgtttgt     2280

cctttttcac tttgaaaagt tggaaggatc tgctgaggcc cagtgcatat gcaatgtata     2340

gtgtctatta tcacattaat ctcaaagaga ttcgaatgac ggtaagtgtt ctcatgaagc     2400

aggaggccct tgtcgtggga tggcatttgg tctcaggcag caccacactg ggtgcgtctc     2460

cagtcatctg taagagcttg ctccagattc tgatgcatac ggctatattg gtttatgtag     2520

tcagttgcat tcattaaatc aactttatca tatgctcttt taaatgtttg gtttatatat     2580

tttctttaaa aatcctgggc tggcacattg actgggaaac ctgagtgaga cccagcaact     2640

gcttctctcc cttctctctc ctgaggtgaa gcttttccag gttttgttga agagatacct     2700

gccagcactt ctgcaagctg aaatttacag aagcaaattc accagaaggg aaacatctca     2760

ggccaacata ggcaaatgaa aagggctatt aaaatatttt tacacctttg aaaattgcag     2820

gcttggtaca aagaggtctg tcatcttccc cctgggatat aagatgatct agctcccggt     2880

agaggatcac cggtgacaac tatagcagtt gtattgtgta acaagtactg ctcccagcag     2940

caattaggga gaaaactagt ctaaattatt tcaactggaa aaaagaaaaa agagtcctct     3000

tcttttccca gccttttgca gaacacagta gacagaactg ccaccttcaa ttggtacttt     3060

attctttgct gctgtttttg tataaaatga cctatcccac gtttttgcat gaatttatag     3120

caggaaaaat caagggattt cctatggaag tcctgcttta ttccaggtga agggaaggaa     3180

gtgtatatac ttttggcaag tcatacagct caaatgtgat gagatttctg atgttagagg     3240

gagatggaga ggcttcctga tgcctcatct gcagggtcct gtgcctctga agttctagcc     3300

atgaggtttc caggtaggac agctgctccc caagcctcct gaggacacag gaagagacgg     3360

aaggagcacc ttgacagact tgtgtgagtc ttctcgaagg agggttgact cagaacccag     3420

agacaataca aaacccctca cttcctctga gagggccaaa tgctgtgagt ctgaagtatg     3480

tgcctggtgt gaaatgatct atggcctgtt tcttacacag gaagccccct gaacctcctg     3540

tacatgtgtt catgttccca gccagctctg agacccagga accaaatatt ccattttggc     3600

ttctgctaga gcagtcatgg ttcctctcct aaaagccatg ggcagcagtt tccgagggcc     3660

tgcatgatcc acctgctgca cgatcctatg agggcttcct gtggcacaca gccctctggg     3720

tgcttgggaa ctagcttcag gcacagcctg attctggtga tccagtgatc tatggaagtc     3780

gtgtcttact ccaggtgaag ggggaaaaaa aaagcctata ctttggcagg ttatgaactt     3840

tgaatgtgat gaaatgacac gtttggctgc atttggatgg tgtcttagaa ccctcattgc     3900

tcagacctga aggctacttc taggagcatg aagtttgagt tttgtgtttt tccaaaggat     3960

acttccttgg ccctttttct ttattgacta gaccaccaga ggaggatgtg tgggattgta     4020

ggcaaaccca cctgtggcat cactgaaaat aaatttgatc atacctaaga ggttaggaaa     4080

tggtgccatt cccaccttag agtgctacat aggtgctttg ggcgtatgta acattagtgt     4140

ccttccttga agccacaagc tagttttctt agttttaaaa tcctgttgta tgaatggcat     4200

ttgtatatta aaacactttt ttaaaggaca gttgaaaagg gcaagaggaa accagggcag     4260

ttctagagga gtgctggtga ctggatagca gttttaagtg gcgttcacct agtcaacacg     4320

accgcgtgtg ttgcccctgc cctgggctcc ccgccatgac atcttcacct tgcagcttgt     4380

gctgagactg acccaagtgc agctagcact gggacacaga tccttgtctt cagcaccttc     4440

caaggagcca acttttattc cctttcctct ctcccctccc cacctcgctt cttcccaatt     4500

tagtaactta gatgcttcca gcacatacgt aggtagctac cccagccggt ttggattaca     4560

ggcctgtgct ggaacatcat ctcagttggc caccttcctg gcaggctgta gacctgacat     4620

tttgagacaa gcctagagtc aggagcaggg actttgactc ttaggaagag cacacatgag     4680

ggcaaggctg ctggcagacg tctccattgt ccttatgttg tctgtgttgt attttttttt     4740

ttttattgac catggtgatt atttttttaa accatcgtta atatactgaa gtgagctata     4800

gcacatatca tgtgcttagt ttgtttattt ttctccatct ccccttggct tcctagagtt     4860

tggacatatt ccaggctaaa tgcttttact caagactaca gaaaggtttg aagtagtgtg     4920

tgcatggcat gcacgtatgt aagtaatctg gggaagaagc aaagatctgt ttcattctta     4980

gcctcaggcc tcatgagggt ctccacaggg ccggagctca ggttacacca ctccttcgtc     5040

cttacaggag atgtagggag aagaatctgc aggctgcttg taggactgtt caccaagggg     5100

gataccagca gcaagagagt gcacccgttt agccctggac cctgtttctt actgtgtgac     5160

ttggctagag ttgggagttc ccccaaaata aacgtgtccc cattttacca gaaccaaacc     5220

tcaacacagc gaagctgtac tgtctttgtg tggcaaagat gttcccttgt aggccccttt     5280

caggtaaccg tcttcacaat gtattttcat cacagtttaa ggagcatcag ccgcttctca     5340

agtgggtagg gaaagcagaa aaacgtacgc aagaggacat ggatccaaaa tgatgatgaa     5400

gcatctccca tggggaggtg atggtgggga gatgatgggc taaacaggca acttttcaaa     5460

aacacagcta tcatagaaaa gaaacttgcc tcatgtaaac tggattgaga aattctcagt     5520

gattctgcaa tggatttttt tttaatgcag aagtaatgta tactctagta ttctggtgtt     5580

tttatattta tgtaataatt tcttaaaacc attcagacag ataactattt aatttttttt     5640

aagaaagttg gaaaggtctc tcctcccaag gacagtggct ggaagagttg gggcacagcc     5700

agttctgaat gttggtggag ggtgtagtgg ctttttggct cagcatccag aaacaccaaa     5760

ccaggctggc taaacaagtg gccgcgtgta aaaacagaca gctctgagtc aaatctgggc     5820

ccttccacaa gggtcctctg aaccaagccc cactcccttg ctaggggtga aagcattaca     5880

gagagatgga gccatctatc caagaagcct tcactcacct tcactgctgc tgttgcaact     5940

cggctgttct ggactctgat gtgtgtggag ggatggggaa tagaacattg actgtgttga     6000

ttaccttcac tattcggcca gcctgacctt ttaataactt tgtaaaaagc atgtatgtat     6060

ttatagtgtt ttagattttt ctaactttta tatcttaaaa gcagagcacc tgtttaagca     6120

ttgtacccct attgttaaag atttgtgtcc tctcattccc tctcttcctc ttgtaagtgc     6180

ccttctaata aacttttcat ggaaaagctc ctgtgccagg agctcagtct gaaaaaaaaa     6240

aaaaaaaaaa aaaaaa                                                     6256


<210>  371
<211>  1321
<212>  DNA
<213>  homo sapiens

<400>  371
aggggtaggg atggttcagc cccgccccgc tagggcgggg cctgcgcctg cgcgctcagc       60

ggccgggcgt gtaacccacg ggtgcgcgcc cacgaccgcc agactcgagc agtctctgga      120

acacgctgcg gggctcccgg gcctgagcca ggtctgttct ccacgcaggt gttccgcgcg      180

ccccgttcag ccatgtcgtc cggcatccat gtagcgctgg tgactggagg caacaagggc      240

atcggcttgg ccatcgtgcg cgacctgtgc cggctgttct cgggggacgt ggtgctcacg      300

gcgcgggacg tgacgcgggg ccaggcggcc gtacagcagc tgcaggcgga gggcctgagc      360

ccgcgcttcc accagctgga catcgacgat ctgcagagca tccgcgccct gcgcgacttc      420

ctgcgcaagg agtacggggg cctggacgtg ctggtcaaca acgcgggcat cgccttcaag      480

gttgctgatc ccacaccctt tcatattcaa gctgaagtga cgatgaaaac aaatttcttt      540

ggtacccgag atgtgtgcac agaattactc cctctaataa aaccccaagg gagagtggtg      600

aacgtatcta gcatcatgag cgtcagagcc cttaaaagct gcagcccaga gctgcagcag      660

aagttccgca gtgagaccat cactgaggag gagctggtgg ggctcatgaa caagtttgtg      720

gaggatacaa agaagggagt gcaccagaag gagggctggc ccagcagcgc atacggggtg      780

acgaagattg gcgtcaccgt tctgtccagg atccacgcca ggaaactgag tgagcagagg      840

aaaggggaca agatcctcct gaatgcctgc tgcccagggt gggtgagaac tgacatggcg      900

ggacccaagg ccaccaagag cccagaagaa ggtgcagaga cccctgtgta cttggccctt      960

ttgcccccag atgctgaggg tccccatgga caatttgttt cagagaagag agttgaacag     1020

tggtgagctg ggctcacagc tccatccatg ggccccattt tgtaccttgt cctgagttgg     1080

tccaaagggc atttacaatg tcataaatat ccttatataa gaaaaaaaat gatctcttat     1140

caattagcac tcactaatgt actactaatt gagcaaccta cgcactcagt tgactacgta     1200

aatctgtcag gtcttttgtg atttcctctg atgcaggaga ggaaaaattg taattgatga     1260

aaataatgaa tgaaaatcaa cagatgaata aatggttctt tataagtgtc catttgtaca     1320

g                                                                     1321


<210>  372
<211>  4265
<212>  DNA
<213>  homo sapiens

<400>  372
ggcggtccgg gcgggtgact ggcggcgggc gccgcggtcg ggctggctgc cgggcagcat       60

ggaggagctg agcagcgtgg gcgagcaggt cttcgccgcc gagtgcatcc tgagcaagcg      120

gctccgcaag ggcaagctgg agtacctggt caagtggcgc ggctggtcct ccaaacataa      180

cagctgggag ccggaggaga acatcctgga cccgaggctg ctcctggcct tccagaagaa      240

ggaacatgag aaggaggtgc agaaccggaa gagaggcaag aggccgagag gccggccaag      300

gaagctcact gccatgtcct cctgcagccg gcgctccaag ctcaaggaac ccgatgctcc      360

ctccaaatcc aagtccagca gttcctcctc ttcctccacg tcatcctcct cttcctcaga      420

tgaagaggat gacagtgact tagatgctaa gaggggtccc cggggccgcg agacccaccc      480

agtgccgcag aagaaggccc agatcctggt ggccaaaccc gagctgaagg atcccatccg      540

gaagaagcgg ggacgaaagc ccctgccccc agagcaaaag gcaacccgaa gacccgtgag      600

cctggccaag gtgctgaaga ccgcccggaa ggatctgggg gccccggcca gcaagctgcc      660

ccctccactc agcgcccccg ttgcaggcct ggcagctctg aaggcccacg ccaaggaggc      720

ctgtggcggc cccagtgcca tggccacccc agagaacctg gccagcctaa tgaagggcat      780

ggccagtagc cccggccggg gtggcatcag ctggcagagc tccatcgtgc actacatgaa      840

ccggatgacc cagagccagg cccaggctgc cagcaggttg gcgctgaagg cccaggccac      900

caacaagtgc ggcctcgggc tggacctgaa ggtgaggacg cagaaagggg agctgggaat      960

gagccctcca ggaagcaaaa tcccgaaggc ccccagcggt ggggctgtgg agcagaaagt     1020

ggggaacaca gggggccccc cgcacaccca tggtgccagc agggtgcctg ctgggtgccc     1080

aggcccccag ccagcaccca cccaggagct gagcctccag gtcttggact tgcagagtgt     1140

caagaatggc atgcccgggg tgggtctcct tgcccgccac gccaccgcca ccaagggtgt     1200

cccggccacc aacccagccc ctgggaaggg cactgggagt ggcctcattg gggccagcgg     1260

ggccaccatg cccaccgaca caagcaaaag tgagaagctg gcttccagag cagtggcgcc     1320

acccacccct gccagcaaga gggactgtgt caagggcagt gctaccccca gtgggcagga     1380

gagccgcaca gcccccggag aagcccgcaa ggcggccaca ctgccagaga tgagcgcagg     1440

tgaggagagt agcagctcgg actccgaccc cgactccgcc tcgccgccca gcactggaca     1500

gaacccgtca gtgtccgttc agaccagcca ggactggaag cccacccgca gcctcatcga     1560

gcacgtattt gtcaccgacg tcactgccaa cctcatcacc gtcacagtga aggagtctcc     1620

caccagcgtg ggcttcttca acctgaggca ttactgaagc cccggcgcca ccagctgcgc     1680

ggtcttactc cccttccctg cctatggtgt cgcttggcta agtgactccc agcccaagcc     1740

ccctcaagag tctgggtcgg gggaggagga gtgggtggcc tccttgatgg gcaggcttgg     1800

aagggacttc tcccgcaccc cactctgtcc caggacatag ggcagggggc ctcactgcct     1860

tgttggtctc caccttgttc ctacctctgc aggcctcttt gctctcccct cttgcctcag     1920

gaaacccggt ggcacctgtg gctccaggtg actgtcttga acagagcggg cttcttcatg     1980

gctgcgttgt tgctgagttt gaactgctcc tccctggcct gcgtgactga atcacagctt     2040

tggtccctgt cttgcagggg ctgaggtgtc aggaggggac ttctggccca ccttgccttc     2100

agccctggag tgggcagaga gtattgtggg gaggcatggc cagtgggact agtgttccct     2160

ccatctggcc acagcttttg ggagatgggg tgggcagggg tggtcctggc tggcattgcc     2220

tgagccggca gtgatgaagt ggggagcttg cccttgacag gtgggggctg gctggggcct     2280

taatgtgaaa agacagtggc aggcagctgg agtagagcga gcccagcagc cctaaaaggc     2340

tgccttcatg gccatctagc cccagttcag ggcagcatcc atagcccaca agccagcgtg     2400

ggtggggcgg gggtggtccc acagctgggt tccacctgaa gagcctccgt gcctcggagc     2460

aggagaggca ggctatggct gccaccctcc ctcctgcctg tgtcccagtg agaactgacc     2520

tgagtcccct tccaaaccca gacccacctc ctgccccagg cccactgaag catgttccat     2580

ttctaaaaag cccagagttc agtgtgtccc aaggaaaacc caaagtggag gtgctcaggt     2640

ccaggggagt ccagtgggca ggacccttgg caggcaagcc cctcccttca ctcccaggac     2700

ctaccttctg ctagtaaagg actggcttca ttctaattat ggcccacaga ctgccccgga     2760

gacctggagg acagcagtgc tggcacttgg gtgtccatgg gcccgtctgc cggctctgcc     2820

tgtgctgcaa gtgttggccg tgggtccagc caacaactcc ctacgtcctg tgtggggccc     2880

tgcccaagtg gatgaggcat tccttgagga gtatcatttt ccctgacaat ccccatcacc     2940

tttaggggtt ccctgcttgg ctcctttcca gctgaaaaac tagacctgtg ccattgggga     3000

agctggacaa agtctagggg gcccgcctgg tagagggtcc cgggaagctg gatctgtcag     3060

cctcggccct gaggcccctg ttaactcaag actgtgagct gcctctaggt ggtcacgtct     3120

gggagctagc ttgtatggct tctgaccagt atcaggattt ctgttctgag agcagcgtgg     3180

gcagcaaggc agggcagccc agaggtggca gcggcaggca atctggtcac taggtctttg     3240

tgatgccaaa aataaaagag ggtggggtgg gtgctttctg ttcctctgat tggatggagt     3300

ccgccagcag gcatggggct acattccagt gcctgactat agggaggcac tcctgattcc     3360

atggagcagc ccggactttg agaatgggct ctggtttgcg gggggcaggc gtaccagact     3420

gcaagacccc ccagtacctc accgtgccaa ataggaagag gtggccttgg tgtagccaaa     3480

tggatctttt taacagtgtg cctttgggga gggacccatg tccatggctt cgttgagggc     3540

catccatatg ccagctgggg gccagcccac agtggccata ttggctgcag caggaatggt     3600

gcccacctcg gcgaattgaa gggctaagag tcccagatag ctaggccaga gctggaagca     3660

gacagtaagg ggaagagctg ctcccacagg agagggagag attccagctc actgcgcagc     3720

ctgggaggag gcgtggatcc tggcacgctg agcctcaggc accagcctcc ctgtgctcga     3780

cagcaaagtc ttgactcctt cctgctgagc actgtgctac cttcactgct ccaaagccag     3840

actaacagct ctccaagccc ttggggtgac tcggcttcca ggagctgttg gagaaatgag     3900

gatgtctgtc cctgtctgcc tgggcaggcc agattcctcc ccagcagccg ggtctctcca     3960

gaccctgatt cggtgccttt ctgtttacca gctacttcaa tcccaaagtt tgaatctgca     4020

gataccttac tcccagccac tttgccttct tactgtgttg tgtgtttttc ctggtgcttc     4080

aagagcgtgt gcagggcaag tgccgtcact gggaactgca ccagatgctc agacttggtt     4140

gtcttatgtt taccaataaa taaaagtaga ctttttctat ttttatttgc tgctatttgt     4200

gtgtgtgttt gtgtttgtgt agctaggtat ctggcacttc tgacgatgca ttgttgcttt     4260

tttcc                                                                 4265


<210>  373
<211>  6008
<212>  DNA
<213>  homo sapiens

<400>  373
atcgcctggg taggtttcca gggaaggcag cgagcaggat cccctactct gcgggcggcg       60

cgaggcgtct ggctcttcgc ggcggcggcg aggggaaagg gagcgcgggg gctgggtgga      120

atcgaggagt gaggaaaaag ggaaggggcg ggggagaggg accagggaag gcgtcggggg      180

gaatctcgcg agggttggag ttttggcgag agtttgtgga agatggcgcc tgttgtgaca      240

ggtcattgaa attatgagac tatcattcaa atggaagcat tatagttctt cggaaccatt      300

atgatctcaa aacgaaagga gaatgataca gatacactgg ctgaggtgtt ttgaggtgca      360

tcgaagtgtt ccaagctgtg acttacctta acatgttctt gaagtaccat ggcgtggatt      420

aaaaggaaat ttggtgagcg gcctccacct aaacgactta ctagggaagc tatgcgaaat      480

tatttaaaag agcgagggga tcaaacagta cttattcttc atgcaaaagt tgcacagaag      540

tcatatggaa atgaaaaaag gtttttttgc ccacctcctt gtgtatatct tatgggcagt      600

ggatggaaga aaaaaaaaga acaaatggaa cgcgatggtt gttctgaaca agagtctcaa      660

ccgtgtgcat ttattgggat aggaaatagt gaccaagaaa tgcagcagct aaacttggaa      720

ggaaagaact attgcacagc caaaacattg tatatatctg actcagacaa gcgaaagcac      780

ttcatgttgt ctgtaaagat gttctatggc aacagtgatg acattggtgt gttcctcagc      840

aagcggataa aagtcatctc caaaccttcc aaaaagaagc agtcattgaa aaatgctgac      900

ttatgcattg cctcaggaac aaaggtggct ctgtttaatc gactacgatc ccagacagtt      960

agtaccagat acttgcatgt agaaggaggt aattttcatg ccagttcaca gcagtgggga     1020

gcctttttta ttcatctctt ggatgatgat gaatcagaag gagaagaatt cacagtccga     1080

gatggctaca tccattatgg acaaacagtc aaacttgtgt gctcagttac tggcatggca     1140

ctcccaagat tgataattag gaaagttgat aagcagaccg cattattgga tgcagatgat     1200

cctgtgtcac aactccataa atgtgcattt taccttaagg atacagaaag aatgtatttg     1260

tgcctttctc aagaaagaat aattcaattt caggccactc catgtccaaa agaaccaaat     1320

aaagagatga taaatgatgg cgcttcctgg acaatcatta gcacagataa ggcagagtat     1380

acattttatg agggaatggg ccctgtcctt gccccagtca ctcctgtgcc tgtggtagag     1440

agccttcagt tgaatggcgg tggggacgta gcaatgcttg aacttacagg acagaatttc     1500

actccaaatt tacgagtgtg gtttggggat gtagaagctg aaactatgta caggtgtgga     1560

gagagtatgc tctgtgtcgt cccagacatt tctgcattcc gagaaggttg gagatgggtc     1620

cggcaaccag tccaggttcc agtaactttg gtccgaaatg atggaatcat ttattccacc     1680

agccttacct ttacctacac accagaacca gggccgcggc cacattgcag tgcagcagga     1740

gcaatccttc gagccaattc aagccaggtg ccccctaacg aatcaaacac aaacagcgag     1800

ggaagttaca caaacgccag cacaaattca accagtgtca catcatctac agccacagtg     1860

gtatcctaac taccgtcttt ttgctaggac ttaaactgac ttgagtgtgg caaaaagtta     1920

acaaaaaagg agaaaaaatg aacaatcgtt tgtggtttct tgggaaaact tttcatacca     1980

ggtgatacta ttcaaaaacc ccgttgtctc cctgcaagtg ctgatttgaa atgcagaagc     2040

cacagtaaaa aaaaaaaaaa aaaaaaaaaa aaagaaaaaa aaatcaaaat gtataaatat     2100

tggaaatcaa gtttttcagc tgttttgttg gttggttggt tggtttttgt ttggttttgt     2160

ttaaatgggc aagaagtaaa taatgtggct ggaatacaag ttgaacaaac tagaagacac     2220

aaatctaaca tagtttttat ggaccaagga acttgtatat tgtataagct ttagtaaaag     2280

gtacattttc accatacctt tttttatatc acggtattat agtacacctt gttaccaaat     2340

aggttgttct cttccccacc cacctttgag cttttgctct aaaatacatt caggttccaa     2400

gcctgaccat ccttgtttaa tctatcatac tcttccaggt tttttttttt tggtctaagg     2460

ctggaacttt tttctttttt ttcagctgaa gtcttatgac ttttcatgag tcaaaattgt     2520

ttggatttca gcaagtcaaa tcttgcaaag gcctgcatat tttttttaag attatatgaa     2580

gtctgtgcaa aagctttaaa aaaatgcctc tgccttgcct gcaatacatg caatgtatgt     2640

taacttagtc tctcttctca gacactgttg gtagttattt ctgtgttttc ctttttttaa     2700

aaaaaaatat ggacttattg tggttatctg agaggttcta acattcacat gcaatttggt     2760

gtggccattt agctattaat gagttaatgg cgcagaactt gttgatattt gaagtgttct     2820

ctcccctttt cccatgacgt aaatacatag gtgtgttcca ggatttgttc aggtttttcc     2880

cccctcctaa tcttgtacat aacttgtatt atgtgtaagt taaacatttt attttgaact     2940

tggaatgttc ccagtgattt cattcagcag ggtattttct gccttgttgg caagtgacaa     3000

aaaatatggg aagtatttgc taccagttgg tagatggtgc ccttaatggt agaatgagga     3060

aaatgtccgc aaaagcatgt tttattatct ttactttttt ggggggttgg agggggtagc     3120

ctagccagaa catcattgta atcttaaaac ataagatgct tttattagat gatcaactaa     3180

aatagctgga agacagtact ttagaaacag atagttgtaa gattataaaa tgcaaatgta     3240

acttatgttt tcattttttt ctctgccttt tttgtttgtt tgttttctct tttccagtac     3300

tgagcatctc cacaaatgtc tcctaactca gaaaatgttt cttttctttt cagttgagat     3360

ttggttgcat tcagggttgt aggttggcct tgcttgctaa ccccgccggt tttaccgtgc     3420

tttcattcct gaactttgtt tatgcctttg tttggtttct tcgaaattgc agcagactca     3480

ttgggctaca tttagtacag gaaccacgtg tgtaatgtta tacaacacag tctagtaata     3540

caatcatccc tcttagagta aaaactacct ctagattgtg gtaagctttt actgtcccat     3600

aaaacaggag ccacagtacc ttatgaatgc aaaactgtaa cttcctacag tgtttcccta     3660

cagaacattg tctttctggt gtcctgggct gttttgaaaa agtttccatt aatagacttt     3720

ttagaaatta ttattagtag catttttttt ccagctttgc tgtcttcatc actcactcta     3780

tgctcagact atgccactgt aaatattctt cctaacatct ttaaatcgcc ttttcctcag     3840

ttttcaaggg gaaggtcatt tgtaaagcac gttaggtggt taaatcagtt attgcggttt     3900

tctcttactg caagcctttt taatcacccc caggctgcat tttattctat atcgcctttt     3960

ttcttcaaat ctgctccaat cactcacttc tctcttataa gctaatcctg cctcacacct     4020

taaatctgtt tcagtgatca agggcagaac tcattgtggc cttatctttc tttgttgtaa     4080

ttgttcactg tctctttctt acagaccact tatttctgag tagtagttat tcctctctat     4140

ggagtcatgg caggaatcat tacacagtgc ttttgttcag agcatggaca tgttcctagt     4200

gctgctttgc tttaacggcc acaagtttcc tccacttcct aggtttggta tttagttaag     4260

gaatcatatt aaattaacca ataacaaaag agatactttt gaagaacaaa ctattcctta     4320

cccatttttg tagctcaaaa ataatttttc aagttcatga ccttattaaa atgaacttgt     4380

gtttttttaa caaacatgta tgttttattt tgatagtttc tttccgtaag ataattgaaa     4440

tattatactg taaacccttt tcttttcttt ttttgaaaag tccaagaatg tacttataca     4500

ggcatttttc cccacctatt tttggccatt ctcataccac agactaaaga gtgaaatgat     4560

ttgtccattg tagcttattg tttatcagta gttcttttgt cagctgctta cattttttct     4620

ttcatggttt tgtgaatcat tttcagtatg taatttatag gaaccttgtc ctctggttat     4680

agtagactgt gtgccctcct ccagtgatgg cattattaga catgctggtc atttaccctc     4740

agaaagactc tcttattaga atggtgagtg cttcagttat agtatgtttg aatttttaaa     4800

aaattctgtt ttagaaatgt atcttatgct ctcatgacta tgcagtttct aaacatacac     4860

atagaagctg agtctctgat ccaatatgtt tttatttgtt ccatttaatt tatcacatag     4920

attgggaagg caagctaaaa gccttaaaaa tgccctttat attttgagtg atttcagcgt     4980

tgaacactag tatactatct aaatttgctg ctcactttct ttaaactgtg gcaattaaag     5040

gcatgtttat acatgactta atcgtgaaat gtttgtcact cttactgcac agacttatct     5100

gcaatcataa ctggttagtt tttttgtttt gttttgtttt attgttttta atgaaactgg     5160

taccatctgt gctttcacaa aaaacttcca atgccatttt tgagaactaa cctaactagt     5220

catgctaacc agaaaatcca ctggggagga ggttcctttt gaaacaaaat gctgttcagt     5280

tagtaaccaa gttactttga ttgcaaaagc agctgtgttt ctgataagta ctgaacaaat     5340

gtgtgtaatt ttctgtgcca gacttatgac tttgttttca agcactgtaa tgtgggatgg     5400

atggttagaa acaataatat attagggttt ctgtttaacc ctttcaggac tgaactgtat     5460

ctccttttgt taattttccc ctgtgttgtg ataaatgttt gccagcattc agtactgtgt     5520

tggtccagat gtaggtttat atgctcattt ttagcttatt tcttgtacct tgcagcatgc     5580

tctacgcatt cagtccttaa ggggtttatt ttacaaactg tgcgcctgta aggtttatta     5640

gcaataagat agaaaattga gcaagtttat accataattt tgtagaaaaa aagaatctgc     5700

tcagttccat atttcatccg tgaaaaactt gcaatacgag cagtttcaag gaataaataa     5760

aaaggaaatg taaaccattg taaaagtctt ctgtcgaatg tgcctgatgc atgtattatc     5820

gtcttttatt tcagaatact tcataaagat aaaattaaat tctatattat agttggtgta     5880

tttacaatct taccatgtac atcacatcaa agtgatagct ctactaattt aatttccttg     5940

tcaatgtttt taactatata gtgctttaaa gagatttttt ttccctgtgt aaaaaaaaaa     6000

aaaaaaaa                                                              6008


<210>  374
<211>  1841
<212>  DNA
<213>  homo sapiens

<400>  374
agaatgattt cactacagac tctctggaaa gcctgggagc tgaattccgg aagatcccca       60

catcgatgaa agcaaagcga agccaccaag ccatcatcat gtccacgtcg ctacgagtca      120

gcccatccat ccatggctac cacttcgaca cagcctctcg taagaaagcc gtgggcaaca      180

tctttgaaaa cacagaccaa gaatcactag aaaggctctt cagaaactct ggagacaaga      240

aagcagagga gagagccaag atcatttttg ccatagatca agatgtggag gagaaaacgc      300

gtgccctgat ggccttgaag aagaggacaa aagacaagct tttccagttt ctgaaactgc      360

ggaaatattc catcaaagtt cactgaagag aagaggatgg ataaggacgt tatccaagaa      420

tggacattca aagaccaagt gagtttgtga gattctaaca gatgcagcat tttgctgcta      480

ccttacaagc ttctcttctg tcaggactcc agaggctgga aagggaccgg gactggaaag      540

ggaccaggac tgaacagact ggttacaaag actccaaaca atttcatgcc ctgtgctgtt      600

acagaggaga acaaaatgct ttcagcaagg atttgaaaac tcttccgtcc ctgcaggaaa      660

ggattgatgc tgatagaaga gcctggacag atgtaatgag aactaaagaa aacagatggc      720

tggagatgac atttatccag ggtcactttg tcaggcccta ggacttaaat cgaagttgaa      780

cttttttttt tttttttaac caaatagata ggggaaggga ggagggagag ggaggacagg      840

gagagaaaat accatgcata aattgtttac tgaattttta tatctgagtg ttcaaaatat      900

ttccaagcct gagtattgtc tattggtata gatttttaga aatcaataat tgattattta      960

tttgcactta ttacaatgcc tgaaaaagtg caccacatgg atgttaagta gaaattcaag     1020

aaagtaagat gtcttcagca actcagtaaa accttacgcc accttttggt ttgtaaaagg     1080

ttttttatac atttcaaaca ggttgcacaa aagttaaaat aatggggtct tttataaatc     1140

caaagtactg tgaaaacatt ttacatattt tttaaatctt ctgactaatg ctaaaacgta     1200

atctaattaa atttcataca gttactgcag taagcattag gaagtgaata tgatatacaa     1260

aatagtttat aaagactcta tagtttctat aatttatttt actggcaaat gtcatgcaac     1320

aataataaat tattgtaaac tttgtggctt ttggtctgtg atgcttggtc tcaaaggaaa     1380

aaataagatg gtaaatgttg atatttacaa acttttctaa agatgtgtct ctaacaataa     1440

aagttaattt tagagtagtt ttatattaat taccaaactt tttcaaaaca aattcttacg     1500

tcaaatatct gggaagtttc tctgtcccaa tcttaaaata taaaatatag atatagaagt     1560

tcatagattg actccttggc atttctattt atgtatccat taaggatgag ttttaaaagg     1620

ctttctcttc atacttttga aaaatttctt ctatgattac agtagctatg tacatgtgta     1680

catctatttt tcccaagcaa tatgttttgg gtttagagtc tgagtgatga ccaagattct     1740

gtgtgttact actgtttgtt taataggaac aaatatagaa ataatattat ctctttgctt     1800

atttcccgtt aaaactataa taaaatgttt ctaggacagc a                         1841


<210>  375
<211>  4209
<212>  DNA
<213>  homo sapiens

<400>  375
cttctggatg tgagacaggc ggatctcacc cacgcctgcc agcagctcct cggagaactg       60

tgttcctggg tcagccctgg cccagaggag cgccggggac ccgcagagtg ctgctgaagt      120

caaggctaca actcacctag gatctggggc gccagccctc cggtgggcag ggcgttctcc      180

tcccccaccc cctccccgca cgatgacatc aagtgtttgg cgttgagttg ctccataaaa      240

gctgcccggg gaagccagga gagcgaaggg cggacgtact cgccacggca cccaggctgc      300

gcgcacgcgg tcccggtgtg cagctggaga gcgagcggcc accgggagcc cccggcacag      360

cccgcgcccg ccccgcagga gcccgcgaag atgccccggc gcagcctgca cgcggcggcc      420

gtgctcctgc tggtgatctt aaaggaacag ccttccagcc cggccccagt gaacggttcc      480

aagtggactt attttggtcc tgatggggag aatagctggt ccaagaagta cccgtcgtgt      540

gggggcctgc tgcagtcccc catagacctg cacagtgaca tcctccagta tgacgccagc      600

ctcacgcccc tcgagttcca aggctacaat ctgtctgcca acaagcagtt tctcctgacc      660

aacaatggcc attcagtgaa gctgaacctg ccctcggaca tgcacatcca gggcctccag      720

tctcgctaca gtgccacgca gctgcacctg cactggggga acccgaatga cccgcacggc      780

tctgagcaca ccgtcagcgg acagcacttc gccgccgagc tgcacattgt ccattataac      840

tcagaccttt atcctgacgc cagcactgcc agcaacaagt cagaaggcct cgctgtcctg      900

gctgttctca ttgagatggg ctccttcaat ccgtcctatg acaagatctt cagtcacctt      960

caacatgtaa agtacaaagg ccaggaagca ttcgtcccgg gattcaacat tgaagagctg     1020

cttccggaga ggaccgctga atattaccgc taccgggggt ccctgaccac acccccttgc     1080

aaccccactg tgctctggac agttttccga aaccccgtgc aaatttccca ggagcagctg     1140

ctggctttgg agacagccct gtactgcaca cacatggacg acccttcccc cagagaaatg     1200

atcaacaact tccggcaggt ccagaagttc gatgagaggc tggtatacac ctccttctcc     1260

caagtgcaag tctgtactgc ggcaggactg agtctgggca tcatcctctc actggccctg     1320

gctggcattc ttggcatctg tattgtggtg gtggtgtcca tttggctttt cagaaggaag     1380

agtatcaaaa aaggtgataa caagggagtc atttacaagc cagccaccaa gatggagact     1440

gaggcccacg cttgaggtcc ccggagctcc cgggcacatc caggaaggac cttgctttgg     1500

accctacaca cttcggctct ctggacactt gcgacacctc aaggtgttct ctgtagctca     1560

atctgcaaac atgccaggcc tcagggatcc tctgctgggt gcctccttgc cttgggacca     1620

tggccacccc agagccatcc gatcgatgga tgggatgcac tctcagacca agcagcagga     1680

attcaaagct gcttgctgta actgtgtgag attgtgaagt ggtctgaatt ctggaatcac     1740

aaaccaagcc atgctggtgg gccattaatg gttggaaaac actttcatcc ggggctttgc     1800

cagagcgtgc tttcaagtgt cctggaaatt ctgctgcttc tccaagcttt cagacaagaa     1860

tgtgcactct ctgcttaggt tttgcttggg aaactcaact tctttcctct ggagacgggg     1920

catctccctc tgatttcctt ctgctatgac aaaaccttta atctgcacct tacaactcgg     1980

ggacaaatgg ggacaggaag gatcaagttg tagagagaaa aagaaaacaa gagatataca     2040

ttgtgatata ttagggacac tttcacagtc ctgtcctctg gatcacagac actgcacaga     2100

ccttagggaa tggcaggttc aagttccact tcttggtggg gatgagaagg gagagagagc     2160

tagagggaca aagagaatga gaagacatgg atgatctggg agagtctcac tttggaatca     2220

gaattggaat cacattctgt ttatcaagcc ataatgtaag gacagaataa tacaatatta     2280

agtccaaatc caacctcctg tcagtggagc agttatgttt tatactctac agattttaca     2340

aataatgagg ctgttccttg aaaatgtgtt gttgctgtgt cctggaggag acatgagttc     2400

cgagatgacc caatctgcct ttgaatctgg aggaaatagg cagaaacaaa atgactgtag     2460

aacttattct ctgtaggcca aatttcattt cagccacttc tgcaggatcc ctactgccaa     2520

cctggaatgg agacttttat ctacttctct ctctctgaag atgtcaaatc gtggtttaga     2580

tcaaatatat ttcaagctat aaaagcagga ggttatctgt gcagggggct ggcatcatgt     2640

atttaggggc aagtaataat ggaatgctac taagatactc catattcttc cccgaatcac     2700

acagacagtt tctgacaggc gcaactcctc cattttcctc ccgcaggtga gaaccctgtg     2760

gagatgagtc agtgccatga ctgagaagga accgacccct agttgagagc accttgcagt     2820

tccccgagaa ctttctgatt cacagtctca ttttgacagc atgaaatgtc ctcttgaagc     2880

atagcttttt aaatatcttt ttccttctac tcctccctct gactctaaga attctctctt     2940

ctggaatcgc ttgaacccag gaggcggagg ttgcagtaag ccaaggtcat gccactgcac     3000

tctagcctgg gtgacagagc gagactccat ctcaaaaaaa aaaaaaaaaa aattattctg     3060

taccatcaca acttttcaca acgatggcaa gccttatgtc ttgggagcct gttttgctag     3120

gcaaagttac aagtgaccta atgggagctc aaatgtgtgt gtgtctctct gtgtgtttgt     3180

gtgtgtgtgt gcactcaaga cctctaacag cctcgaagcc tggggtggca tcccggcctt     3240

gccattagca tgcctcatgc atcatcagat gacaaggaca accctcatga cgaagcaaca     3300

tgaattaggg ggcctcttgg ccttggtcca aaattgtcaa tcagaaatga acataaagga     3360

ctccagagca gtgggactgt ctgtcaaaag actctgtata tcttttgtgg atgagttttg     3420

tgagagaaca gagagaccat tgtacctggc acaagggctg ttcatgaaaa gggagactta     3480

ctgggaggtg caagacagtg gcatttctcc tctcctcttg ctgctcagca cagccctgga     3540

ttgcagcccc gaggctgaga ccagacaaag cccgggaggc agaaagatgc tccaagaacc     3600

aacactatca atgtctttgc aaatcctcac aggattcctg tgggtccagc tttggaactg     3660

ggaaaccttt cttcggatcc gcactcattc cactgatgcc agctgcccct gaaggatgcc     3720

agtactgtgg tgtgtgagtc tcagcagccg cccacacgct cctaactctg ctgcatggca     3780

gatgcctagg tggaaatagc aaaaacaagg cccaggctgg ggccagggcc agaggggaag     3840

gccctggatt ctcactcatg tgagatcttg aatctctttc tttgttctgt ttgtttagtt     3900

agtatcatct ggtaaaatag ttaaaaaaca acaaaaaact ctgtatctgt ttctagcatg     3960

tgctgcattg actctattaa tcacatttca aattcaccct acattcctct cctcttcact     4020

agcctctctg aaggtgtcct ggccagccct ggagaagcac tggtgtctgc agcacccctc     4080

agttcctgtg cctcagccca caggccactg tgataatggt ctgtttagca cttctgtatt     4140

tattgtaaga atgattataa tgaagataca cactgtaact acaagaaatt ataaatgttt     4200

ttcacatca                                                             4209


<210>  376
<211>  5561
<212>  DNA
<213>  homo sapiens

<400>  376
agggggccga ctggcgcggc tctggagagc gctcctccgc cccgcgcgcc gtccctgcgc       60

cccgctccgc ccgcgcctct ctcccagcgc cgcgcctcgg gcgtaaagag cgcgcccctc      120

gcaccgcagc cagtgccgac cgcagcagcc cagccccagc cttcctccgc ctccgcctct      180

ctctcctcct cctcctccgc cgccggacac gcagccgcag gccgggaccg ggacgcagct      240

ggggagtcag ggacgcgcgc agccagccct tccccctccg gctcccgcac cgccggccgc      300

ctcccctcgc cctcctactc tcccctccct gctccttcgc tttttcctcc tcctcctctc      360

ccggccccgg ctgccagcac catgtccgca gggggagatt ttgggaatcc actgagaaaa      420

ttcaagttgg tgttcttggg ggagcagagc gtcgggaaga cgtctctgat tacgaggttc      480

atgtacgaca gcttcgacaa cacataccag gcaaccattg ggattgactt cttgtcaaaa      540

accatgtact tggaggaccg cacggtgcga ctgcagctct gggacacagc tggtcaggag      600

aggttccgca gcctgatccc cagctacatc cgggactcca cggtggctgt ggtggtgtac      660

gacatcacaa atctcaactc cttccaacag acctctaagt ggatcgacga cgtcaggaca      720

gagaggggca gtgatgttat catcatgctg gtgggcaaca agacggacct ggctgataag      780

aggcagataa ccatcgagga gggggagcag cgcgccaaag aactgagcgt catgttcatt      840

gagaccagtg cgaagactgg ctacaacgtg aagcagcttt ttcgacgtgt ggcgtcggct      900

ctacccggaa tggagaatgt ccaggagaaa agcaaagaag ggatgatcga catcaagctg      960

gacaaacccc aggagccccc ggccagcgag ggcggctgct cctgctaatg cagagccgac     1020

ctgtggcttc ccatgacact ccttgcttgt tgtgttgctt cctattggct agcttcctaa     1080

ggggggaggg aaccgagtta tcaagatggg aggatttttc ttttctctct gtctttagga     1140

gtagggtggg atggggaggg aggctgggca tcagggatca catcactctt aacggctgtt     1200

acttaaacaa ctattttttg gtttggttgt aatatattgt actttattaa gattgccaaa     1260

aactgttaaa atttaaaaaa aatttaaatc atgtgtatac aattttttgc cagataaaaa     1320

tgtagtcatt tttatttgaa agatgtgctt tttgtttttg tatatttgta aacttataga     1380

gaaccttttc cacacacctc ctccttcctg ttctctttga accattcatc acctctgcct     1440

tcctcctatc cccagcccaa taaattaaaa caattaactg agcaaattaa ttaggcttca     1500

gtctggggcc atctggcccc actctctagg ccctactcca gttaaatcaa acattggttg     1560

aacacatcag cctctgaaaa ggtagctctg actcttgtct ttccatggcc agagtgggtc     1620

gtcaacctcg tgtggagctg agaccaaggt ctgtgggctc taggcagccc ggcagcagcc     1680

cccagaggaa ctgctcccac ctctccttct ctttccctga aaagccttga agggggttga     1740

gggtacaggc aaccttgtgt tctctgtgcc ctcagggact ggcagagcaa gaggccatca     1800

gaaggacgag gtgctgttgg caattgcagc tgcgtggtgc gtggtttata gactggggtg     1860

ccatgtgtac ttctgaaaat attttaacca gcccacccag cagtcagtac acatgcctgg     1920

gccaagtcta agaaactcag tgtgtgatgt tgggcagtgt gccatcctga agccttcctc     1980

ctggatgtca gggaagctgg accacctgga gttgatcctc tgtgatgggg aggcgggggg     2040

gggggggggt gttgtctgca gaaccaccac cttgaaagat ccatgttctt agagcctcag     2100

ctgctaatat tgttgagtgc tttctggaaa agctgatttg ttgctatgtt ttcaccccag     2160

tggcatggcg cagttgaagt ctttgtggac atatctttgt ggctactgtg gctgcgctgt     2220

ggtcacctga ggatgtggtt caggtggggt ctccagaagg ctgcttgccc ccagagagcc     2280

atctcttcca tttttgattc attcctgaga atggcttagt cctgagaatc tgcaaagtct     2340

ctgaagagaa ctctctcttc ccactaagtg atataaccta cttggccagc attccaaata     2400

gactcagact cactgccctg agcctgcaca gagccaggtg caatgggcag tgagtctggc     2460

caaaatgtaa accccaccct ccctgctgtc attggctctc cctccaggct gctgctgggc     2520

atgtcataga tgggatgaat gaccatctgg ggtatggtgg gctgaactcc acaaggtcgt     2580

tggaatgaat tttgaaactt ctcagaaatt aatctgaaat ggcaggcagt aagtgcagca     2640

gaatctggca ggactgatat ttgtgcagtg ggcctgccac acaccctctg cctaggaggc     2700

tgtatgccag agctcatctc tagcaaggaa tttatcttca ggtgaagaag agaggaagca     2760

ggatcccact gagcacctct tgcagaaggc aaggaccaat gtttgaacgt gtttcagatg     2820

tcatgtgttt agtttttata tgtgtgtaca taattatata tagagataga cttgtgtata     2880

caccttccac aaacacatcc tcacggagat acatgtgctc aatgtatatt cttgtttctc     2940

ctgctctcaa gttggaactt gcattgtgat aagttttgga aattcaaaag tactgcaacg     3000

tgttgaaata agaaatactt aatattgtca aataacttgt gattgtcttg ccatcaataa     3060

aataatgcat agttgtgtta aactacaggc aaacatagcc cacgggaata tctccaccat     3120

ttctctatgt actttatatg cacgggtgtg catgcctgtg tgggccagtg tccccccacc     3180

atgggcacac ccccaagtgg tgcttgttgg aagagtgctt acttacctcg agagaattta     3240

caggagtcca catgacagtg tcctgcctgg ttggcagcgg gggccatcac ctgtggcctc     3300

tgagaccgcc ccatttacag gaatctgcac tgggtctcag tgaatgaacg tatggtagat     3360

ttttattttc ttggcactaa agattagctt ttttaaaaaa acatcccata aaacagtaga     3420

aactcagttc ccttctcagg ggcacacaca tccaaggcac cgtggactgt gtttccatcc     3480

tggcctagag gagcagtaaa agatagcatt tggtttgaca tggccttagt gagtcctgcc     3540

tttcctagca tgcacacaac atcctctctt tgagtttggg ttctccccag ccccttggcc     3600

tctgaggctg agggtggctt cctcccatcc tcccatctca gtggttccat ggcgctccct     3660

tcggcacgtg cggtttccgc ccctcccttc ctggggtgtg gaaaggcagc cagacctctt     3720

tttcagaagt tgttggttcc ctgatttttg tcttgagcag gcaccatccc tgtccccttg     3780

cttgcaggta gaattggcac agagttaagg ttccataata aactgttagg tgctcttgaa     3840

gaagatgtca tggcattgcc tcagcacccc agcaagagca ttgcatcttt gctgaatcca     3900

gatgggttag cagagggcaa attggaggat tcctttgagg aaatgttctc aattgagcaa     3960

ttcagtccct ctccccaaag actagacgtg acctggcaga ttagcaggat cctcttggcc     4020

ttcttttttg gggatggtgg gagtgaaggg ggtgaatctt aaaagcttat caacaaagct     4080

cctgttctgc aggcatcagg aaagttgagt gtaagatgga aaaagcaaac agcctattta     4140

caagtggaaa cacattggtt ctgatcactc ctaacttgct gggtgatcat acatacatca     4200

acatgaaggt gtgacatcag aatcatgagc accatggctg cagttgtgtg atccaaggct     4260

agttggcttg gtagctgttg gcagcagttt cccttggtca gaggcctcct tgctatctat     4320

cgctgctctc ttcttgtcat ccttaaacat tcagtcatgt tcccaggtct gaggggagca     4380

atggccagac cagtttcagt atctctggca acagaaacaa ggattgaaat ggtggtagtt     4440

aagagtgcag acacatctgg ggtgcaacgt ctgcatcatc ctggtggcta gccagtgcgg     4500

ggaggccctg ccctgggata ccagttgtga caataaaggg atggccctcc tggcttcagc     4560

atcctgcagg tagagcagcc tcattccttc acaagatgga aggcaggtga ggatgtcagg     4620

atgagatggg accaggtagc cgaggacagt gaggcatgtc tgagccactt gaggggcagc     4680

tgaacagaag gatgtctgtg tgcatcaacc gagcagattg tgcgcacact cgtttccgaa     4740

ctgcctctcc ccaaagaatg tgaggcattg tcaccttgtt acagctatgt gaagcagagc     4800

tgtcacaact tttcctgtct acaggcagga aaaccaggat ggagaagggc aacttgctta     4860

ttaagatcac ccagcaagtt aggagtgatc agaaccagtg aagtttccat ttttcatcca     4920

ttgctgccct gtgtgtgaac aaatgtgact ccatatttat tacacagcaa ggactgctgt     4980

gtgtgggtgt gttcctcaga ccatctctac tctttttggt taggacacta ggttcttccc     5040

agcatatgag tgagaatatt ggtggtattt tgggctcctc tactgcacaa gggccagtcc     5100

ccaagtctac tctgattgat tgtcatgggc acccacacag atcaggacac cctttgaatt     5160

tttgtttgac atgaactatt taggtgttcc aaaaccttgg gatctcaatg tgcaaactcc     5220

ttggactcca gacccctgtc tggttggcac tcccagcagt gtgtggtttc atcaggaaat     5280

ccttgcagca ggggtttaga tggttccttc aggaggtggg aagcctccat agcattgaag     5340

gccagcctgc atctcgcggt gtgtgtccac ttctcccctc actttcccct cacccatccc     5400

tttaaagtga ttggctgtga ggagcacaga gggtggcaat tccatctgtt atgggctcag     5460

aagacatagc cgccatgttg atttcacatt aaactgtgta aaatgtggaa aagactcagc     5520

atgttggtca aacaataaac tgtcctaatt ctcaaaacaa a                         5561


<210>  377
<211>  5274
<212>  DNA
<213>  homo sapiens

<400>  377
cggccgcccc tctggctgct ctgcctggtc gcgtgctggc tcctgggcgc cggggccgaa       60

gccgacttct ccatcctgga cgaggcgcaa gtgctggcga gccagatgcg gaggctggcg      120

gccgaggagc tgggggtcgt caccatgcag cggatattca actcctttgt ttacactgag      180

aaaatctcaa atggagaaag tgaagtacag cagctagcca aaaaaatccg agagaagttc      240

aaccgttact tggatgtggt caatcggaac aagcaagttg tagaagcatc ctatacggct      300

cacctaacct ctcccctaac tgcaattcaa gactgctgta ctatcccacc ttccatgatg      360

gaattcgatg ggaactttaa taccaatgtg tctagaacaa ttagttgtga tcgactttct      420

actactgtta atagccgggc cttcaatcca ggacgagact taaattcagt tcttgcagac      480

aacctgaaat ccaaccctgg aattaagtgg caatatttca gttcagaaga aggaattttc      540

actgttttcc cagcacacaa gttccggtgt aagggcagct acgaacaccg cagtagaccc      600

atctacgtct ctacagtccg gccgcagtca aagcacatag tagtgattct ggaccacggg      660

gcttcagtca cagacactca gcttcagatt gccaaggacg ctgctcaggt catcctcagc      720

gccatcgatg aacatgacaa gatttctgtg ttaactgtgg cagataccgt ccggacttgc      780

tcactagacc agtgctataa gaccttcttg tctccagcca ccagtgagac aaaaaggaaa      840

atgtccacct ttgttagcag cgtgaagtct tcagacagtc ctacccagca cgcagtggga      900

ttccaaaagg catttcagct gattcgaagt acaaacaata acacaaagtt ccaagcaaat      960

acagacatgg tcatcattta cctgtcagct ggcattacat caaaggactc ttcggaagaa     1020

gataaaaaag cgactctcca agtcatcaat gaagaaaata gctttctaaa caactctgta     1080

atgattctca cctatgccct catgaacgat ggggtgactg gtttgaaaga gctggctttt     1140

ctgagggatc tagctgaaca gaattcaggg aagtacggtg tgccagaccg gatggccttg     1200

cctgtgatta agggcagcat gatggtgctg aatcagttga gcaacctgga gaccacagtg     1260

ggcaggttct acacaaacct tcccaaccgg atgattgatg aagccgtctt cagcctgccc     1320

ttctctgatg agatgggaga tggtttgata atgactgtga gtaaaccctg ttattttgga     1380

aacctacttc tgggaattgt aggtgtggac gtgaatctgg cttacattct tgaagacgtg     1440

acgtattacc aagactcttt ggcttcctat acttttctca tagacgacaa aggatataca     1500

cttatgcacc catctcttac caggccatat ttattgtcag agcccccact tcatactgac     1560

atcatacatt atgaaaatat tccaaaattt gaattagttc ggcaaaatat cctaagcctc     1620

cctctgggca gccagattat cgcagtccct gtgaactcat ccctgtcttg gcacataaac     1680

aagctgagag aaactggaaa ggaagcctac aatgttagct atgcctggaa gatggtacaa     1740

gacacttcct ttattctgtg tattgtggtg atacaaccag aaatacctgt gaaacaactg     1800

aagaacctca acactgttcc cagcagcaag ctgctgtacc accggctgga tctccttggc     1860

cagcccagtg cttgcctcca cttcaaacag ctggcaaccc tagaaagtcc caccatcatg     1920

ctgtctgctg gcagcttttc ctccccctat gagcacctca gccagccaga gacaaagcgc     1980

atggtagagc actacaccgc ctatctcagc gacaacaccc gcctcattgc taacccgggc     2040

ctcaaattct ctgtcagaaa tgaagtaatg gctaccagcc acgtcacaga tgaatggatg     2100

acacaaatgg aaatgagtag cctgaacact tacattgtcc gccgttacat agcaacaccc     2160

aatggcgtcc tcagaattta tcctggttcc ctcatggaca aagcatttga tcccactagg     2220

agacaatggt atctccatgc agtagctaat ccagggttga tttctttgac tggtccttac     2280

ttagatgttg gaggagctgg ttatgttgtg acaatcagtc acacaattca ttcatccagt     2340

acacagctgt cttctgggca cactgtggct gtgatgggca ttgacttcac actcagatac     2400

ttctacaaag ttctgatgga cctattacct gtctgtaacc aagatggtgg caacaaaata     2460

aggtgcttca taatggagga caggggttat ctggtggcgc acccgactct catcgacccc     2520

aaaggacatg cacctgtgga gcagcagcac atcacccaca aggagcccct ggtagcaaat     2580

gatatcctca accaccccaa ctttgtaaag aaaaacctgt gcaacagctt cagtgacaga     2640

acggtccaga ggttttataa attcaacacc agccttgcgg gggatttgac gaaccttgtg     2700

catggcagcc actgttccaa atacagatta gcaaggatcc caggaaccaa cgcgtttgtt     2760

ggcattgtca acgaaacctg cgactctctt gccttctgtg cctgcagcat ggtggaccga     2820

ctctgtctca actgtcaccg aatggaacaa aatgaatgtg aatgtccttg tgagtgccct     2880

ctagaggtca atgagtgcac tggcaacctc accaatgcag agaaccgaaa ccccagctgc     2940

gaggtccacc aggagccggt gacatacaca gctattgacc ctggcctgca agatgctctt     3000

caccagtgtg tcaacagcag gtgcagtcag aggctggaaa gtggggactg ttttggggtg     3060

ctggattgtg aatggtgcat ggtggacagt gatggaaaga ctcacctgga caaaccctac     3120

tgtgcccccc agaaagaatg cttcgggggg attgtgggag ccaaaagtcc ctacgttgat     3180

gacatgggag caataggtga tgaggtgatc acattaaaca tgattaaaag cgcccctgtg     3240

ggtcctgtgg ctggagggat catgggatgc atcatggtct tggtcctggc ggtgtatgcc     3300

taccgccacc agattcatcg ccggagccat cagcatatgt ctcctcttgc tgcccaagaa     3360

atgtcagtgc gtatgtccaa cctggagaat gacagagatg aaagggacga cgacagccac     3420

gaagacagag gcatcatcag caacactcgg tttatagctg cggtcatcga acgacatgca     3480

cacagtccag aaagaaggcg ccgctactgg ggtcgatcag gaacagaaag tgatcatggt     3540

tacagcacca tgagcccaca ggaggacagt gaaaatcctc catgcaacaa tgaccccttg     3600

tcagccgggg tcgatgtggg aaaccatgat gaggacttag acctggatac cccccctcag     3660

actgctgccc tactaagtca caagttccac cactaccggt cacaccaccc tacacttcat     3720

catagccacc acttacaggc ggccgtcacg gtacacactg tcgatgcaga atgctaacaa     3780

tctcctcacc tccacgccaa gatgagatct gggagctaca gaatgttctg gaaagaaaaa     3840

gaaccggctt aaaacccaca gcaagagacc tcccttgtgt ttgtgctttg tgcagagttg     3900

tttgagtcat ttcctgcctg tcgacatggt taaaaacgag agaaacaaca acacagtcac     3960

atttgtgaag atgtgaggct ggttctgaaa tggaggggaa ataagcctga tgaacagacc     4020

tgccataaca ctaatggaag gtaacagaag gcgaacctcc aaacacagag acggaacctg     4080

caagtgaagc tgagccagag gaatgttcca aagagccaga agcattcagc tctccttaac     4140

tggaagagag aaaaatctgc tcacccagag actggaatgt ggcacatgca gatacaaatg     4200

tgtgcattga agatttcgct ttgtttctta gcggtacctg gataccacag ttgctgtatg     4260

gaactcatgt tatgctctaa acgatgcatc tcagaatttc taagtaaagg attatttttc     4320

tactatttat tgaactttca aacattctca aactttgggg aaaaggaaag gaaacacagg     4380

agaagttttc agcagttgcc ccgagctgtt ttgtgtgtaa tgaagtggtt ctttgattaa     4440

ggagctctat ttcttattta actgatatcc cactgcccca ctccacaaaa taggaaaatg     4500

aagaaatctt tctctctgac ttgtttacat catttcacgg aaacacatct ttgtttgtaa     4560

tgcagtattc tttctctgtg tttgacagag atggggaggg gcagaggaat ttaagaggtt     4620

ttaaaagaaa tgttatgttt cttatgactt gtttccactc ctcgtacaat gctattctta     4680

ggtttctacg aaacctaatg ttagaaccgc atcctttcag ctaagggagg gttggattta     4740

ttttccttgt tttagagact acaaattttt aaatatccca ttttgactga gaatattgac     4800

atataaggga agaagttttc taaattgtga aagtctggtt cttaattaaa gaattttttt     4860

tttaatatca cggttaaaag ctgctgccag ttagccaaga cattatccac caaattgctt     4920

tgtgatttat acagggatta atcaaatctg gctactataa catggggcat tgtaacttta     4980

aagtagtgtt ttaattacag tgatgtattt tagactcaca ttttgtgatt caaatatgtt     5040

ataaaggcat tcttgcacca tggtaaagaa tgtgtgtggt aaatctccgt ttatatgtag     5100

ttggaaaaaa ttcactgaat aatgttttaa tgatagggta ttatgataca atgtaaaaaa     5160

caattggttc ttcagcagta cagaaagtaa actatatatg tgctatcagg aaaccccttc     5220

atactgtgta taaaattgca atctagtgaa ataaaccgta tgcaatggac catt           5274


<210>  378
<211>  5274
<212>  DNA
<213>  homo sapiens

<400>  378
cggccgcccc tctggctgct ctgcctggtc gcgtgctggc tcctgggcgc cggggccgaa       60

gccgacttct ccatcctgga cgaggcgcaa gtgctggcga gccagatgcg gaggctggcg      120

gccgaggagc tgggggtcgt caccatgcag cggatattca actcctttgt ttacactgag      180

aaaatctcaa atggagaaag tgaagtacag cagctagcca aaaaaatccg agagaagttc      240

aaccgttact tggatgtggt caatcggaac aagcaagttg tagaagcatc ctatacggct      300

cacctaacct ctcccctaac tgcaattcaa gactgctgta ctatcccacc ttccatgatg      360

gaattcgatg ggaactttaa taccaatgtg tctagaacaa ttagttgtga tcgactttct      420

actactgtta atagccgggc cttcaatcca ggacgagact taaattcagt tcttgcagac      480

aacctgaaat ccaaccctgg aattaagtgg caatatttca gttcagaaga aggaattttc      540

actgttttcc cagcacacaa gttccggtgt aagggcagct acgaacaccg cagtagaccc      600

atctacgtct ctacagtccg gccgcagtca aagcacatag tagtgattct ggaccacggg      660

gcttcagtca cagacactca gcttcagatt gccaaggacg ctgctcaggt catcctcagc      720

gccatcgatg aacatgacaa gatttctgtg ttaactgtgg cagataccgt ccggacttgc      780

tcactagacc agtgctataa gaccttcttg tctccagcca ccagtgagac aaaaaggaaa      840

atgtccacct ttgttagcag cgtgaagtct tcagacagtc ctacccagca cgcagtggga      900

ttccaaaagg catttcagct gattcgaagt acaaacaata acacaaagtt ccaagcaaat      960

acagacatgg tcatcattta cctgtcagct ggcattacat caaaggactc ttcggaagaa     1020

gataaaaaag cgactctcca agtcatcaat gaagaaaata gctttctaaa caactctgta     1080

atgattctca cctatgccct catgaacgat ggggtgactg gtttgaaaga gctggctttt     1140

ctgagggatc tagctgaaca gaattcaggg aagtacggtg tgccagaccg gatggccttg     1200

cctgtgatta agggcagcat gatggtgctg aatcagttga gcaacctgga gaccacagtg     1260

ggcaggttct acacaaacct tcccaaccgg atgattgatg aagccgtctt cagcctgccc     1320

ttctctgatg agatgggaga tggtttgata atgactgtga gtaaaccctg ttattttgga     1380

aacctacttc tgggaattgt aggtgtggac gtgaatctgg cttacattct tgaagacgtg     1440

acgtattacc aagactcttt ggcttcctat acttttctca tagacgacaa aggatataca     1500

cttatgcacc catctcttac caggccatat ttattgtcag agcccccact tcatactgac     1560

atcatacatt atgaaaatat tccaaaattt gaattagttc ggcaaaatat cctaagcctc     1620

cctctgggca gccagattat cgcagtccct gtgaactcat ccctgtcttg gcacataaac     1680

aagctgagag aaactggaaa ggaagcctac aatgttagct atgcctggaa gatggtacaa     1740

gacacttcct ttattctgtg tattgtggtg atacaaccag aaatacctgt gaaacaactg     1800

aagaacctca acactgttcc cagcagcaag ctgctgtacc accggctgga tctccttggc     1860

cagcccagtg cttgcctcca cttcaaacag ctggcaaccc tagaaagtcc caccatcatg     1920

ctgtctgctg gcagcttttc ctccccctat gagcacctca gccagccaga gacaaagcgc     1980

atggtagagc actacaccgc ctatctcagc gacaacaccc gcctcattgc taacccgggc     2040

ctcaaattct ctgtcagaaa tgaagtaatg gctaccagcc acgtcacaga tgaatggatg     2100

acacaaatgg aaatgagtag cctgaacact tacattgtcc gccgttacat agcaacaccc     2160

aatggcgtcc tcagaattta tcctggttcc ctcatggaca aagcatttga tcccactagg     2220

agacaatggt atctccatgc agtagctaat ccagggttga tttctttgac tggtccttac     2280

ttagatgttg gaggagctgg ttatgttgtg acaatcagtc acacaattca ttcatccagt     2340

acacagctgt cttctgggca cactgtggct gtgatgggca ttgacttcac actcagatac     2400

ttctacaaag ttctgatgga cctattacct gtctgtaacc aagatggtgg caacaaaata     2460

aggtgcttca taatggagga caggggttat ctggtggcgc acccgactct catcgacccc     2520

aaaggacatg cacctgtgga gcagcagcac atcacccaca aggagcccct ggtagcaaat     2580

gatatcctca accaccccaa ctttgtaaag aaaaacctgt gcaacagctt cagtgacaga     2640

acggtccaga ggttttataa attcaacacc agccttgcgg gggatttgac gaaccttgtg     2700

catggcagcc actgttccaa atacagatta gcaaggatcc caggaaccaa cgcgtttgtt     2760

ggcattgtca acgaaacctg cgactctctt gccttctgtg cctgcagcat ggtggaccga     2820

ctctgtctca actgtcaccg aatggaacaa aatgaatgtg aatgtccttg tgagtgccct     2880

ctagaggtca atgagtgcac tggcaacctc accaatgcag agaaccgaaa ccccagctgc     2940

gaggtccacc aggagccggt gacatacaca gctattgacc ctggcctgca agatgctctt     3000

caccagtgtg tcaacagcag gtgcagtcag aggctggaaa gtggggactg ttttggggtg     3060

ctggattgtg aatggtgcat ggtggacagt gatggaaaga ctcacctgga caaaccctac     3120

tgtgcccccc agaaagaatg cttcgggggg attgtgggag ccaaaagtcc ctacgttgat     3180

gacatgggag caataggtga tgaggtgatc acattaaaca tgattaaaag cgcccctgtg     3240

ggtcctgtgg ctggagggat catgggatgc atcatggtct tggtcctggc ggtgtatgcc     3300

taccgccacc agattcatcg ccggagccat cagcatatgt ctcctcttgc tgcccaagaa     3360

atgtcagtgc gtatgtccaa cctggagaat gacagagatg aaagggacga cgacagccac     3420

gaagacagag gcatcatcag caacactcgg tttatagctg cggtcatcga acgacatgca     3480

cacagtccag aaagaaggcg ccgctactgg ggtcgatcag gaacagaaag tgatcatggt     3540

tacagcacca tgagcccaca ggaggacagt gaaaatcctc catgcaacaa tgaccccttg     3600

tcagccgggg tcgatgtggg aaaccatgat gaggacttag acctggatac cccccctcag     3660

actgctgccc tactaagtca caagttccac cactaccggt cacaccaccc tacacttcat     3720

catagccacc acttacaggc ggccgtcacg gtacacactg tcgatgcaga atgctaacaa     3780

tctcctcacc tccacgccaa gatgagatct gggagctaca gaatgttctg gaaagaaaaa     3840

gaaccggctt aaaacccaca gcaagagacc tcccttgtgt ttgtgctttg tgcagagttg     3900

tttgagtcat ttcctgcctg tcgacatggt taaaaacgag agaaacaaca acacagtcac     3960

atttgtgaag atgtgaggct ggttctgaaa tggaggggaa ataagcctga tgaacagacc     4020

tgccataaca ctaatggaag gtaacagaag gcgaacctcc aaacacagag acggaacctg     4080

caagtgaagc tgagccagag gaatgttcca aagagccaga agcattcagc tctccttaac     4140

tggaagagag aaaaatctgc tcacccagag actggaatgt ggcacatgca gatacaaatg     4200

tgtgcattga agatttcgct ttgtttctta gcggtacctg gataccacag ttgctgtatg     4260

gaactcatgt tatgctctaa acgatgcatc tcagaatttc taagtaaagg attatttttc     4320

tactatttat tgaactttca aacattctca aactttgggg aaaaggaaag gaaacacagg     4380

agaagttttc agcagttgcc ccgagctgtt ttgtgtgtaa tgaagtggtt ctttgattaa     4440

ggagctctat ttcttattta actgatatcc cactgcccca ctccacaaaa taggaaaatg     4500

aagaaatctt tctctctgac ttgtttacat catttcacgg aaacacatct ttgtttgtaa     4560

tgcagtattc tttctctgtg tttgacagag atggggaggg gcagaggaat ttaagaggtt     4620

ttaaaagaaa tgttatgttt cttatgactt gtttccactc ctcgtacaat gctattctta     4680

ggtttctacg aaacctaatg ttagaaccgc atcctttcag ctaagggagg gttggattta     4740

ttttccttgt tttagagact acaaattttt aaatatccca ttttgactga gaatattgac     4800

atataaggga agaagttttc taaattgtga aagtctggtt cttaattaaa gaattttttt     4860

tttaatatca cggttaaaag ctgctgccag ttagccaaga cattatccac caaattgctt     4920

tgtgatttat acagggatta atcaaatctg gctactataa catggggcat tgtaacttta     4980

aagtagtgtt ttaattacag tgatgtattt tagactcaca ttttgtgatt caaatatgtt     5040

ataaaggcat tcttgcacca tggtaaagaa tgtgtgtggt aaatctccgt ttatatgtag     5100

ttggaaaaaa ttcactgaat aatgttttaa tgatagggta ttatgataca atgtaaaaaa     5160

caattggttc ttcagcagta cagaaagtaa actatatatg tgctatcagg aaaccccttc     5220

atactgtgta taaaattgca atctagtgaa ataaaccgta tgcaatggac catt           5274


<210>  379
<211>  3744
<212>  DNA
<213>  homo sapiens

<400>  379
tttcagccaa ccagactgga gcagctgcga gtgctacatc ttggctgtct gaagcgattg       60

gctcctctct ggggagtgga gggtgttcag ttattaatga ccgctgagca ggcagcacca      120

tgtcagtgtg acaactgatc gggtgaacga tgcaccacta accaccatgg aaacaaggaa      180

aaataaagcc agctcacagg atctctcttc actggattga gagcctcagc ctgccgactg      240

agaaaaagag ttccaggaaa aagaaggaat cccggctgca gcctcctgcc ttcctttata      300

ttttaaaata gagagataag attgcgtgca tgtgtgcata tctatagtat atattttgta      360

cactttgtta cacagacaca caaatgcacc tatttatacc gggcaagaac acaaccatgt      420

gattatctca accaaggaac tgaggaatcc agcacgcaag gacatcggag gtgggctagc      480

actgaaactg cttttcaagg aggtgaagca ttccacagat aatcagctac tctattcagg      540

gaaggagtgt aaacatcacc actttttgca tgtttgcata aaaaaggccc actgaatcag      600

ttaaagacga ggaagaggag gagaaagaga aagaagagga agatgttggg caacatttat      660

ttaacatgct ccacagcccg gaccctggca tcatgctgct attcctgcaa atactgaaga      720

agcatgggat ttaaatattt tacttctaaa taaatgaatt actcaatctc ctatgaccat      780

ctatacatac tccaccttca aaaagtacat caatattata tcattaagga aatagtaacc      840

ttctcttctc caatatgcat gacatttttg gacaatgcaa ttgtggcact ggcacttatt      900

tcagtgaaga aaaactttgt ggttctatgg cattcatcat ttgacaaatg caagcatctt      960

ccttatcaat cagctcctat tgaacttact agcactgact gtggaatcct taagggccca     1020

ttacatttct gaagaagaaa gctaagatga aggacatgcc actccgaatt catgtgctac     1080

ttggcctagc tatcactaca ctagtacaag ctgtagataa aaaagtggat tgtccacggt     1140

tatgtacgtg tgaaatcagg ccttggttta cacccagatc catttatatg gaagcatcta     1200

cagtggattg taatgattta ggtcttttaa ctttcccagc cagattgcca gctaacacac     1260

agattcttct cctacagact aacaatattg caaaaattga atactccaca gactttccag     1320

taaaccttac tggcctggat ttatctcaaa acaatttatc ttcagtcacc aatattaatg     1380

taaaaaagat gcctcagctc ctttctgtgt acctagagga aaacaaactt actgaactgc     1440

ctgaaaaatg tctgtccgaa ctgagcaact tacaagaact ctatattaat cacaacttgc     1500

tttctacaat ttcacctgga gcctttattg gcctacataa tcttcttcga cttcatctca     1560

attcaaatag attgcagatg atcaacagta agtggtttga tgctcttcca aatctagaga     1620

ttctgatgat tggggaaaat ccaattatca gaatcaaaga catgaacttt aagcctctta     1680

tcaatcttcg cagcctggtt atagctggta taaacctcac agaaatacca gataacgcct     1740

tggttggact ggaaaactta gaaagcatct ctttttacga taacaggctt attaaagtac     1800

cccatgttgc tcttcaaaaa gttgtaaatc tcaaattttt ggatctaaat aaaaatccta     1860

ttaatagaat acgaaggggt gattttagca atatgctaca cttaaaagag ttggggataa     1920

ataatatgcc tgagctgatt tccatcgata gtcttgctgt ggataacctg ccagatttaa     1980

gaaaaataga agctactaac aaccctagat tgtcttacat tcaccccaat gcatttttca     2040

gactccccaa gctggaatca ctcatgctga acagcaatgc tctcagtgcc ctgtaccatg     2100

gtaccattga gtctctgcca aacctcaagg aaatcagcat acacagtaac cccatcaggt     2160

gtgactgtgt catccgttgg atgaacatga acaaaaccaa cattcgattc atggagccag     2220

attcactgtt ttgcgtggac ccacctgaat tccaaggtca gaatgttcgg caagtgcatt     2280

tcagggacat gatggaaatt tgtctccctc ttatagctcc tgagagcttt ccttctaatc     2340

taaatgtaga agctgggagc tatgtttcct ttcactgtag agctactgca gaaccacagc     2400

ctgaaatcta ctggataaca ccttctggtc aaaaactctt gcctaatacc ctgacagaca     2460

agttctatgt ccattctgag ggaacactag atataaatgg cgtaactccc aaagaagggg     2520

gtttatatac ttgtatagca actaacctag ttggcgctga cttgaagtct gttatgatca     2580

aagtggatgg atcttttcca caagataaca atggctcttt gaatattaaa ataagagata     2640

ttcaggccaa ttcagttttg gtgtcctgga aagcaagttc taaaattctc aaatctagtg     2700

ttaaatggac agcctttgtc aagactgaaa attctcatgc tgcgcaaagt gctcgaatac     2760

catctgatgt caaggtatat aatcttactc atctgaatcc atcaactgag tataaaattt     2820

gtattgatat tcccaccatc tatcagaaaa acagaaaaaa atgtgtaaat gtcaccacca     2880

aaggtttgca ccctgatcaa aaagagtatg aaaagaataa taccacaaca cttatggcct     2940

gtcttggagg ccttctgggg attattggtg tgatatgtct tatcagctgc ctctctccag     3000

aaatgaactg tgatggtgga cacagctatg tgaggaatta cttacagaaa ccaacctttg     3060

cattaggtga gctttatcct cctctgataa atctctggga agcaggaaaa gaaaaaagta     3120

catcactgaa agtaaaagca actgttatag gtttaccaac aaatatgtcc taaaaaccac     3180

caaggaaacc tactccaaaa atgaacaaaa aaaaaaaaag cgaaagactg cagttgtgct     3240

aaaaacaaaa caaaacaaac aaacaaacaa aaaagtaaaa aaagattact ttcgagagag     3300

aagtttaagc ttcaccaatg ctgctcctga ccaatggaaa tatgtacaac ttcagcattt     3360

taagtaactg gcttcaaggg gtactgtggc aaccaaataa aataactcca ttttctaaaa     3420

ctttcatgta acttttatgt ctggactaca gttcaagtgg acaaaaacat ttctgtattt     3480

tttttaagta aataagagta gttgaactga gcaatacctc ctcctgtgtt gtattacaca     3540

tattagccac gagtttttgc agtgaccaga taaacttgaa ttgacacgtg gtgtaataaa     3600

atggacaaat tctgtagagt agacacagtg agtatgtgga cctcttttat aaggaaaaat     3660

acattttgga ttaaaatcaa ttgcttctgt cttgttttgt ttctaaataa agaataattt     3720

ctgggaaaaa aaaaaaaaaa aaaa                                            3744


<210>  380
<211>  11425
<212>  DNA
<213>  homo sapiens

<400>  380
gcgcgcgcgc aggctcttca gctggagcgg acacacggtg tgcgaaccga acagaataac       60

ccgcccccag cgggatgtga aggactccgg gtgaggccgg ccacgccccg cacggatggg      120

aaggccattg tgactatgtg gtgattacag ttgtcttact actgagtttc ctactgaaat      180

catggaggag aaacagcaga ttatattggc taatcaagat ggtggaacag tggcaggagc      240

agcacctacc ttctttgtca tcttaaagca gccaggaaat ggcaaaactg atcaaggaat      300

tttggttact aatcaggatg cctgtgcttt ggctagtagt gtgtcatcac cagtaaaatc      360

taaagggaag atttgccttc cagctgattg tactgtgggt ggaatcactg ttaccctcga      420

taacaatagt atgtggaatg agttctatca tcgaagcaca gagatgattc tgaccaagca      480

aggaagacgc atgtttcctt actgtcgtta ttggataaca ggtttagatt caaatttgaa      540

gtatattctt gtcatggata tatctcctgt ggataaccat cgttataagt ggaatggtcg      600

ttggtgggaa cctagtggga aggctgaacc tcatgttttg gggagggttt tcattcatcc      660

agaatctcct tccacaggtc attattggat gcatcaacca gtatctttct ataaactcaa      720

acttaccaac aatacactgg accaagaagg gcatatcatc ttgcactcta tgcatcgtta      780

cctgccgagg cttcatttgg tgcctgcaga aaaggctgtg gaggtgatac aattaaatgg      840

ccctggtgtc cacactttta ccttcccaca gactgaattc tttgcagtaa cagcttatca      900

gaacattcag attactcagc tgaaaataga ttacaatcca tttgccaaag gctttcggga      960

tgatgggctg aataataagc cccagagaga tggaaaacaa aagaacagct ctgaccaaga     1020

agggaataat atttccagtt cttctggtca tcgggtccgt cttacagaag gtcaggggtc     1080

agagatacaa ccaggtgatt tggatccttt gtcaaggggt catgaaacat caggcaaggg     1140

tttggagaag acttccctta atataaaacg agactttctt ggtttcatgg atactgattc     1200

agcacttagt gaagttcctc aattgaagca agagatttct gaatgtctta ttgccagcag     1260

ttttgaagat gactcccgtg tagcctcacc gttagaccag aacggaagct tcaatgttgt     1320

tattaaagag gaacctctag atgattatga ctacgaactt ggtgagtgcc cagaaggggt     1380

cactgtgaaa caggaagaga cagatgaaga gacggatgta tactcaaaca gtgatgatga     1440

tcctatacta gagaaacagc taaagaggca caataaagtt gacaacccag aagctgacca     1500

tctatcttct aaatggcttc caagcagccc atcaggtgtt gctaaagcta aaatgttcaa     1560

attagacact ggaaagatgc cagtagtcta tctggagccc tgtgctgtca ccagaagcac     1620

agttaagatt tctgaactcc ccgataacat gctttccaca tctcgaaagg ataaatcttc     1680

tatgttggca gaattggaat atttgcctac atacattgaa aattccaatg agactgcctt     1740

ctgcttaggc aaggaatcag aaaatggtct tagaaaacat tcaccagatc tcagagtggt     1800

acaaaaatat cccttactga aagagcctca gtggaaatat cctgatatat ctgacagcat     1860

tagcacagaa agaatactcg acgattcaaa ggattcagtt ggagactcac tttcaggaaa     1920

agaggacttg ggcagaaaga gaacaactat gcttaagatt gcaacagccg caaaggtagt     1980

gaatgctaat cagaatgcct ctccaaatgt ccctggaaaa agaggaaggc cacgaaaatt     2040

gaaactctgt aaggcaggac gaccacctaa gaacacagga aagtctttaa tttctacaaa     2100

gaatacacct gtaagccctg ggagtacctt tccagatgtg aagcctgatc tggaagatgt     2160

ggatggtgtt ctctttgttt cctttgaatc aaaggaagct ctagacattc atgcagttga     2220

tgggacaaca gaagaatctt ctagtctcca ggcatcaacc acaaatgact caggttacag     2280

agcaagaatt tcccagttgg aaaaggaatt gatagaagat ttgaagactt tgcggcacaa     2340

gcaggtgata catcctggtc ttcaagaagt gggcttaaaa ttgaattcag tggatccaac     2400

aatgagcatt gatcttaaat acttgggagt acagttacct ttggctccag ctactagctt     2460

tcctttttgg aaccttacag gaaccaaccc tgcctctcct gatgcgggat ttccctttgt     2520

ttctaggaca gggaaaacca atgatttcac taagatcaag ggatggaggg gaaaatttca     2580

tagtgcttct gcatctagga atgaaggtgg aaattcagaa agttcactga aaaatcgttc     2640

tgctttctgt agtgataagc tagatgaata cttggaaaat gaaggcaagc tgatggaaac     2700

aagcatgggt ttttcttcta atgctcccac atctcctgtg gtgtaccagc ttcccactaa     2760

gagtaccagt tatgtacgaa cacttgatag tgtactaaag aagcaatcta ctatttcccc     2820

ttctacctct tattctttga aacctcattc tgtaccccct gtctctcgaa aggcaaagtc     2880

tcaaaacaga caggcaactt tcagtggccg aactaaatca tcttataaat ccattttacc     2940

ataccctgtt tcaccaaagc agaaatactc tcatgtgatt ctaggagata aggttaccaa     3000

gaattcttca ggcatcatct cagaaaatca ggcgaataac tttgttgtgc caactttgga     3060

tgaaaatata tttccaaagc agattagttt gcggcaggca cagcagcagc agcaacagca     3120

acagggaagt cgccctccag gcttgtctaa atctcaggtg aagctaatgg acctggaaga     3180

ctgtgcactt tgggaaggaa aaccaaggac atacatcaca gaagagcgag cagatgtatc     3240

cttaacaact ctacttacag ctcaagcatc cctcaaaact aaacctatcc acacaatcat     3300

aaggaaacga gcccctccct gcaacaatga cttctgtcga ctgggttgtg tatgttccag     3360

tctagctttg gagaagcgcc aacctgctca ctgccgccga ccagactgca tgtttggttg     3420

tacttgtttg aaaagaaaag ttgtacttgt taaaggagga tccaaaacta agcattttca     3480

gaggaaggct gctcatcgag atccagtatt ttatgatact ctgggagagg aggcaaggga     3540

ggaggaagaa ggaatcaggg aggaggagga acaattgaaa gagaaaaaga agagaaagaa     3600

gctagaatac actatatgtg agacagagcc tgaacagcct gttcgacatt acccattatg     3660

ggtaaaagta gaaggtgaag tagatccaga accagtttat atccccacgc cttctgtcat     3720

tgagcctatg aaaccattgt tattgcctca gccagaagtt ttatctccta ctgtgaaggg     3780

caaactgctc actggaatta aatctccacg gtcatatact cccaaaccca atcctgtgat     3840

tcgggaagag gacaaagatc cagtctactt gtactttgaa agtatgatga cttgtgctcg     3900

agttcgagta tatgagcgaa aaaaagagga ccagagacaa ccatcttcct cctcctcccc     3960

atctccatca tttcagcagc aaacttcatg tcattctagc cctgagaacc ataataatgc     4020

aaaggaacct gattctgaac agcagccctt aaaacaactc acctgtgact tggaggatga     4080

ttctgataaa ttacaagaaa agagctggaa gtcttcctgc aatgaaggag aatcctcttc     4140

tacttcttat atgcatcaga ggtcacctgg tggtcccacc aaactgattg agatcatctc     4200

agactgcaac tgggaggaag atcggaacaa gattttgagc atcttatccc agcacatcaa     4260

tagcaacatg ccacaatcac ttaaggtggg cagcttcatc attgagttgg cttctcagcg     4320

aaagagccgg ggtgagaaga accctcctgt ttattcttct cgtgtgaaaa tctctatgcc     4380

atcatgtcaa gaccaagatg atatggctga gaaatctgga tcagagactc ctgatggtcc     4440

attgtcccct gggaaaatgg aggatatctc tcctgtgcag acagatgccc tggattcagt     4500

gagggagaga ttacatggag gcaaaggtct gcctttttat gcagggcttt ctcctgcagg     4560

gaagcttgtg gcctataaac gtaaacccag ttcaagtaca tctgggctta tccaggtagc     4620

atccaatgcc aaggtggctg catccaggaa accacgtacc ctgttgcctt caacatccaa     4680

ttccaaaatg gcatcctcct ctggcactgc aacaaatcgc cctgggaaga atctgaaggc     4740

gtttgtccca gcaaaacggc caattgaaaa tgctgctcaa attccagtgg ctactccaca     4800

ggtctctcct aacacagtga aacgtgctgg acctcgattg ttgttgattc cagtgcagca     4860

gggttctcct actcttagac ctgtctcaaa cacacaactt cagggacatc ggatggtctt     4920

gcagcctgtt aggagtccaa gtggaatgaa cttattcagg caccctaatg ggcagattgt     4980

ccagcttcta cctttgcatc agcttcgagg ctctaatacc cagcccaact tacagcctgt     5040

catgtttcgg aacccagggt ctgtgatggg aatccggtta cctgctcctt ccaaaccctc     5100

tgagactccg ccatcttcca cttcgtcctc tgctttctct gtcatgaatc ctgtaattca     5160

agctgttggg tcttcttcag cagtgaatgt tatcactcag gcaccatcat tgctttcctc     5220

tggagctagt tttgtgtctc aggctggtac attgaccctg aggatttctc ctcctgaacc     5280

acaaagcttt gcaagtaaaa caggctctga aaccaaaata acttatagct caggaggaca     5340

gcctgttggt acagccagtc ttattcctct ccagtctggt agttttgcct tgttacagct     5400

cccaggacaa aagcctgttc ctagctccat tcttcagcat gttgcttccc ttcagatgaa     5460

gagagaatct cagaatccag accagaaaga tgaaacaaac tcaataaaaa gagagcaaga     5520

aacgaagaag gttctacagt cagaaggaga ggctgtagac cctgaggcta atgtaataaa     5580

acaaaactca ggagctgcta cctcagaaga aactctgaat gattccttgg aagatagggg     5640

tgatcatttg gatgaagaat gccttccaga agaaggttgt gcaactgtca aaccatctga     5700

gcattcctgt atcactgggt cacatacaga tcaagattat aaagatgtta atgaagaata     5760

tggggctagg aatcgtaaga gttccaaaga aaaagtggct gttctggaag ttaggaccat     5820

ttctgaaaaa gccagtaata agacagtcca aaatttaagt aaagtacagc atcaaaaact     5880

tggtgatgtg aaggtggaac agcagaaagg atttgacaat ccagaagaaa actcaagtga     5940

atttccagtc acctttaagg aagaaagtaa atttgaattg tcaggaagca aagttatgga     6000

gcagcaatct aatctacagc cagaggccaa agagaaggaa tgtggagact ctctggagaa     6060

agacagggaa agatggagaa aacatctgaa gggcccctta accaggaaat gtgttggagc     6120

ttcacaggaa tgtaagaaag aggcagacga gcagttaatt aaagaaacaa agacatgtca     6180

ggaaaattca gatgtgtttc agcaagaaca aggcatctct gacttacttg gaaaaagtgg     6240

aattactgaa gatgccagag ttttgaaaac tgaatgtgat tcttggagta ggatttctaa     6300

tccttcagcc ttctccattg ttcctaggag agctgcaaaa agcagcagag ggaatggaca     6360

ttttcagggt cacttactgc tacctggaga acagatacaa ccaaagcaag agaagaaggg     6420

tgggagaagc agtgctgact tcactgtttt ggatttggaa gaagatgatg aagatgataa     6480

tgagaaaact gatgattcta ttgatgaaat tgtggatgtt gtttctgact accagagtga     6540

ggaggttgat gatgtagaaa agaataactg tgtagaatac attgaggatg atgaggagca     6600

cgtggacatt gagactgtag aagagctctc agaggaaatt aatgttgctc acctgaagac     6660

cacagcggcc cacacacagt cattcaaaca gccgtcctgt actcacatct ctgcagatga     6720

aaaagcagct gaaaggagtc gaaaggctcc accaattcct ctaaaactga agcctgatta     6780

ctggagtgac aaactacaga aagaagcaga agcgtttgct tattatcgcc ggacacacac     6840

tgccaatgag cggcggcggc gtggtgaaat gagggatctc tttgagaaat taaagatcac     6900

attgggatta cttcattctt ccaaggtttc caaaagtctc attcttactc gagccttcag     6960

tgaaattcag ggactaacag atcaggcaga caaattgata ggacagaaaa atctcctgac     7020

tcgaaaacgg aatattctga tacggaaagt atcgtctctt tcaggtaaga cagaagaagt     7080

ggtcctgaag aagctagagt atatttatgc aaaacagcaa gcactagagg cacaaaaaag     7140

aaaaaagaag atgggatcag atgagtttga catatctccc agaattagca aacagcagga     7200

aggatcttct gcatcatctg tagatcttgg acagatgttt ataaataaca ggagggggaa     7260

acctttgatt ctttccagaa aaaaagacca ggccacagaa aatacctcac ccttgaacac     7320

tccacacacc tctgccaacc ttgtgatgac tccgcaaggg caattgctca ccctaaaagg     7380

tcccctattc tcaggaccag tggtagctgt ttctcctgat ctcttagaat ctgatcttaa     7440

gcctcaagtt gccggtagtg ctgtggctct accagaaaat gacgacttat ttatgatgcc     7500

acgaattgtt aatgtgacat cattggccac agagggaggt ttggtagata tgggtggcag     7560

caaatatcct catgaagttc ctgatagcaa gccatctgac catctgaaag acaccgtcag     7620

gaatgaagat aattccttag aggataaggg tagaatctct tccagaggaa acagagatgg     7680

cagagtgacg ttgggtccaa cgcaggtttt tctggcaaac aaagattctg gttatccaca     7740

aatagttgac gtttccaata tgcagaaagc acaagagttc ttacctaaaa agatttctgg     7800

tgatatgaga gggattcagt ataaatggaa agagagtgaa tcaagagggg agagagtgaa     7860

gtcaaaggat tcttcatttc ataaattaaa gatgaaagat ctcaaggact caagcataga     7920

gatggaactg aggaaagtaa catcagctat agaggaagca gctcttgatt ccagtgaact     7980

gctgactaac atggaagatg aggatgatac tgatgagaca ctgacttcac tgctcaatga     8040

aattgccttt cttaatcaac aactaaatga tgactctgtt ggcctggctg aactacccag     8100

ctctatggat acagagttcc caggggatgc tcggcgggct tttattagta aggttcctcc     8160

tggaagcaga gcaactttcc aggttgagca cttgggaact ggtttgaaag agttgcctga     8220

tgttcaaggg gagagtgact ctatcagtcc cctcctcttg cacttggaag acgatgactt     8280

ttctgagaat gaaaaacaac ttgcagaacc agcctctgag ccagatgtcc ttaagattgt     8340

tattgactct gaaataaagg attccctcct ttccaacaag aaagctattg atggagggaa     8400

gaatacttct ggcctccctg cagagcccga aagtgtgtcc tcacccccca ccctacacat     8460

gaagactggc ttggagaaca gcaacagcac agacactttg tggaggccta tgccaaagtt     8520

ggcccctcta ggtttaaaag tagctaatcc ttccagtgat gcagatggtc agagtctcaa     8580

ggtgatgcct tgtttggcac ctatagctgc caaagttggg tcagttggac acaaaatgaa     8640

cttaacaggg aatgaccagg aaggccggga aagcaaggtg atgcctacat tggcacctgt     8700

tgtggctaaa ttgggcaact cgggggcctc accaagttct gcagggaaat gaacttactt     8760

gtccttaagc agaagccagg ctgtgagggg aaatagatct cacctccttt ctctgcaggc     8820

atctgtttgt ttgtgtctta gaacttggat ccttgacttc aatgatgcag tggataatga     8880

tgggagaaag ggggtagggt gctgaccctg gtataagaag tactctgaaa ttctgatcat     8940

gttaaaatgt gttacctcac ttgtggtgct gggtcccctc atcctctcta agaagatgtg     9000

atccattact gaacatgagg tgcccctctt acccaaggaa tttataacat gactctggct     9060

ccacagtggt ttctagttct tcccccacaa gcgaaagagc tgtttgcaac tttggagttg     9120

ctgtagactg aactgtagct tgtagctgtt gaattaagtc caaaatctaa ggaatgcgat     9180

ggacttgtgc aaagggatcc agaagagaca ctttttagtt gatgtttcaa gaatagggag     9240

agagaggatg ggtaccatgg aataccaaag tgaaggactt tgtgtcattc agtaaaattt     9300

tcttttttca tatcctaagt agctcccatt ccctcacctt ttcaatcaga attaacaaat     9360

tcaagccttc agtaaagtag ggatgctttt aacttttatt attaattatt ttgagatctt     9420

aaaaaaatag tagttctccc ttattatttt tgtgggcatt gaaaagctca tttcacagta     9480

ccagagattt ttactgggag tatatatttt ggaggtaggc atagagggag ccctacccct     9540

tccacaaatt acgttactca agagacagct aaaataaaat gcattatctc cccagaccag     9600

agacagtggc caaaataaaa aatcatgggg ctggaaattt cccaaatcaa accagcctcc     9660

tggtgcttga aggtttcatt cactattacc tgcacaggat gtaaagaaaa gtcacagtag     9720

gcactcttta ccagggaaat aaggcagtat ttgaatcaca agatatattt tttatctgca     9780

accatggatc caatgatctg tagagctttt tcactcatta actgtcagga tatgaaggac     9840

tgacagtctg taaagatatt tatatttttg tatagttgtt ttcatagatt tctcaaaggc     9900

tgaagttttc aacctagaag atgagatttg tattgagtat agaaatgatg tttcctatct     9960

agtttgtaaa taatcatggt gcacttgagg ggtctcttgg aaactcctag ggggtcaaga    10020

atcactattc tgaaactgta tagactggga tttagctgct gcattttgcc tttcttaaat    10080

aattatattt tggaatgtaa cccctgttct gtcttcattg acaggatttg cttgtgttgt    10140

taaaacacta acacaagagc ttccagtgcc tgggccgtgc ctaggtgatg ctatttcttc    10200

tatatctcct gtcttcttta tcccaaatcc cactcagcat atcttcagac ctaggttgta    10260

agaccaactt tggattggat ctagccagtg aattattatt tccatggttg gttccctttc    10320

tgttaactct ggtaatcaac agattgaaaa cggtggaaga acttctgaaa attgcagtgg    10380

gagcaaattc ttgttggttt tgtgctgctt gcctttctag atctgctcat cagcacttaa    10440

ccttccctcc tctaaaggtt actaaagaag cctgaagtag gtaaagagtg ctcctcagct    10500

tcttatcctt ccactcttta cccagcagat ttcattcaat gccttagcca aggagtccag    10560

cacctgtctc ccctgctaat aattgtcctt agagatgcta gtactttaat ccaggtatag    10620

cagtttcccg ttattttctt gcttgtcgtt cccctacatt tcctcctgat ttcccaagac    10680

tctctttgtg gcttttgagg gtcagccaag gagcaggcaa gtgagtgaac aatcctcagg    10740

aaaagaagga ccattttagc ttaacacttc cttttttttt tttttttttt taagaagaat    10800

ataggtaaac aggtaatgat tcttgattgg agataccatt tgactcttga tgagagttgt    10860

acgaagatgg aaatgaggga tgattccagg cgttttaggg ggaaggctgc agataccatt    10920

ctaaccccca agatactgtg ttctcaagac ctcttagaac taggtgttgt cagggataat    10980

ttgaggaggg cttagtcttc agaacaatcc tgcagtcttg acagaaatct aaaatctcca    11040

aaaactccta ccctttaacc ttaccctagg gggaactgat ctatgaatat tacatgtgtg    11100

attatgaaag gtgaagttga gtgagaggag ttgaggaacg tggaagacag tgagctctca    11160

ccctaacact ataagaagca tgatctcaat agaccaataa ttcacctttt tatacatctg    11220

taaataaatg gaatgttttt aagaatataa ttatgtcaga tttagcattt tcttttatat    11280

attaaatata tatatctttc cttttctgct ttcgaaaagt gactattttt ttagaaatct    11340

aagaacagaa gtttggtgat tgaaaggtag aatatataaa cctgaaataa agcagttaaa    11400

acaattaaag cagaaaaaaa aaaaa                                          11425


<210>  381
<211>  1902
<212>  DNA
<213>  homo sapiens

<400>  381
ggcactgggc aggaagggga gggggagcga gcgcgagaaa tgcagaggct gcagcggcgg       60

cggcggcggc agtagcggca gcggcgacga cggcggcggc agcgctccaa ctggctcctc      120

gctccgggct ccgccgtcga gccgggagag agcctccgcc agcggccagg caccagccag      180

acgacgccag cgaccccggc ctctcggcgg caccgcgcta actcaggggc tgcataggca      240

cccagagccg aactccaaga tgggaggcaa gctcagcaag aagaagaagg gctacaatgt      300

gaacgacgag aaagccaagg agaaagacaa gaaggccgag ggcgcggcga cggaagagga      360

ggggaccccg aaggagagtg agccccaggc ggccgcagag cccgccgagg ccaaggaggg      420

caaggagaag cccgaccagg acgccgaggg caaggccgag gagaaggagg gcgagaagga      480

cgcggcggct gccaaggagg aggccccgaa ggcggagccc gagaagacgg agggcgcggc      540

agaggccaag gctgagcccc cgaaggcgcc cgagcaggag caggcggccc ccggccccgc      600

tgcgggcggc gaggccccca aagctgctga ggccgccgcg gccccggccg agagcgcggc      660

ccctgccgcc ggggaggagc ccagcaagga ggaaggggaa cccaaaaaga ctgaggcgcc      720

cgcagctcct gccgcccagg agaccaaaag tgacggggcc ccagcttcag actcaaaacc      780

cggcagctcg gaggctgccc cctcttccaa ggagaccccc gcagccacgg aagcgcctag      840

ttccacaccc aaggcccagg gccccgcagc ctctgcagaa gagcccaagc cggtggaggc      900

cccggcagct aattccgacc aaaccgtaac cgtgaaagag tgacaaggac agcctatagg      960

aaaaacaata ccacttaaaa caatctcctc tctctctctc tctctctctc tctatctctc     1020

tctctatctc ctctctctct ctcctctcct atctctcctc tctctctctc ctatactaac     1080

ttgtttcaaa ttggaagtaa tgatatgtat tgcccaagga aaaatacagg atgttgtccc     1140

atcaagggag ggagggggtg ggagaatcca aatagtattt ttgtggggaa atatctaata     1200

taccttcagt caactttacc aagaagtcct ggatttccaa gatccgcgtc tgaaagtgca     1260

gtacatcgtt tgtacctgaa actgccgcca catgcactcc tccaccgctg agagttgaat     1320

agcttttctt ctgcaatggg agttgggagt gatgcgtttg attctgccca cagggcctgt     1380

gccaaggcaa tcagatcttt atgagagcag tattttctgt gttttctttt taatttacag     1440

cctttcttat tttgatattt ttttaatgtt gtggatgaat gccagctttc agacagagcc     1500

cacttagctt gtccacatgg atctcaatgc caatcctcca ttcttcctct ccagatattt     1560

ttgggagtga caaacattct ctcatcctac ttagcctacc tagatttctc atgacgagtt     1620

aatgcatgtc cgtggttggg tgcacctgta gttctgttta ttggtcagtg gaaatgaaaa     1680

aaaaaaaaaa aaaaagtctg cgttcattgc agttccagtt tctcttccat tctgtgtcac     1740

agacaccaac acaccactca ttggaaaatg gaaaaaaaaa acaaaaaaaa aacaaaaaaa     1800

tgtacaatgg atgcattgaa attatatgta attgtataaa tggtgcaaca gtaataaagt     1860

taaacaatta aaaagaagta ataaagacaa aaaaaaaaaa aa                        1902


<210>  382
<211>  2809
<212>  DNA
<213>  homo sapiens

<400>  382
aactgagcga ggagcaattg attaatagct cggcgagggg actcactgac tgttataata       60

acactacacc agcaactcct ggcttcccag cagccggaac acagacagga gagagtagcg      120

agggagttgg gtctccaggt tgtgcgagga gcaaatgatg accgccaagg ccgtagacaa      180

aatcccagta actctcagtg gttttgtgca ccagctgtct gacaacatct acccggtgga      240

ggacctcgcc gccacgtcgg tgaccatctt tcccaatgcc gaactgggag gcccctttga      300

ccagatgaac ggagtggccg gagatggcat gatcaacatt gacatgactg gagagaagag      360

gtcgttggat ctcccatatc ccagcagctt tgctcccgtc tctgcaccta gaaaccagac      420

cttcacttac atgggcaagt tctccattga ccctcagtac cctggtgcca gctgctaccc      480

agaaggcata atcaatattg tgagtgcagg catcttgcaa ggggtcactt ccccagcttc      540

aaccacagcc tcatccagcg tcacctctgc ctcccccaac ccactggcca caggacccct      600

gggtgtgtgc accatgtccc agacccagcc tgacctggac cacctgtact ctccgccacc      660

gcctcctcct ccttattctg gctgtgcagg agacctctac caggaccctt ctgcgttcct      720

gtcagcagcc accacctcca cctcttcctc tctggcctac ccaccacctc cttcctatcc      780

atcccccaag ccagccacgg acccaggtct cttcccaatg atcccagact atcctggatt      840

ctttccatct cagtgccaga gagacctaca tggtacagct ggcccagacc gtaagccctt      900

tccctgccca ctggacaccc tgcgggtgcc ccctccactc actccactct ctacaatccg      960

taactttacc ctggggggcc ccagtgctgg ggtgaccgga ccaggggcca gtggaggcag     1020

cgagggaccc cggctgcctg gtagcagctc agcagcagca gcagccgccg ccgccgccgc     1080

ctataaccca caccacctgc cactgcggcc cattctgagg cctcgcaagt accccaacag     1140

acccagcaag acgccggtgc acgagaggcc ctacccgtgc ccagcagaag gctgcgaccg     1200

gcggttctcc cgctctgacg agctgacacg gcacatccga atccacactg ggcataagcc     1260

cttccagtgt cggatctgca tgcgcaactt cagccgcagt gaccacctca ccacccatat     1320

ccgcacccac accggtgaga agcccttcgc ctgtgactac tgtggccgaa agtttgcccg     1380

gagtgatgag aggaagcgcc acaccaagat ccacctgaga cagaaagagc ggaaaagcag     1440

tgccccctct gcatcggtgc cagccccctc tacagcctcc tgctctgggg gcgtgcagcc     1500

tgggggtacc ctgtgcagca gtaacagcag cagtcttggc ggagggccgc tcgccccttg     1560

ctcctctcgg acccggacac cttgagatga gactcaggct gatacaccag ctcccaaagg     1620

tcccggaggc cctttgtcca ctggagctgc acaacaaaca ctaccaccct ttcctgtccc     1680

tctctccctt tgttgggcaa agggctttgg tggagctagc actgccccct ttccacctag     1740

aagcaggttc ttcctaaaac ttagcccatt ctagtctctc ttaggtgagt tgactatcaa     1800

cccaaggcaa aggggaggct cagaaggagg tggtgtgggg acccctggcc aagagggctg     1860

aggtctgacc ctgctttaaa gggttgtttg actaggtttt gctaccccac ttccccttat     1920

tttgacccat cacaggtttt tgaccctgga tgtcagagtt gatctaagac gttttctaca     1980

ataggttggg agatgctgat cccttcaagt ggggacagca aaaagacaag caaaactgat     2040

gtgcacttta tggcttggga ctgatttggg ggacattgta cagtgagtga agtatagcct     2100

ttatgccaca ctctgtggcc ctaaaatggt gaatcagagc atatctagtt gtctcaaccc     2160

ttgaagcaat atgtattata aactcagaga acagaagtgc aatgtgatgg gaggaacata     2220

gcaatatctg ctccttttcg agttgtttga gaaatgtagg ctattttttc agtgtatatc     2280

cactcagatt ttgtgtattt ttgatgtaca ctgttctcta aattctgaat ctttgggaaa     2340

aaatgtaaag catttatgat ctcagaggtt aacttattta agggggatgt acatatattc     2400

tctgaaacta ggatgcatgc aattgtgttg gaagtgtcct tggtgccttg tgtgatgtag     2460

acaatgttac aaggtctgca tgtaaatggg ttgccttatt atggagaaaa aaatcactcc     2520

ctgagtttag tatggctgta tatttctgcc tattaatatt tggaattttt tttagaaagt     2580

atatttttgt atgctttgtt ttgtgactta aaagtgttac ctttgtagtc aaatttcaga     2640

taagaatgta cataatgtta ccggagctga tttgtttggt cattagctct taatagttgt     2700

gaaaaaataa atctattcta acgcaaaacc actaactgaa gttcagataa tggatggttt     2760

gtgactatag tgtaaataaa tacttttcaa caataaaaaa aaaaaaaaa                 2809


<210>  383
<211>  2533
<212>  DNA
<213>  homo sapiens

<400>  383
gcgggtgtgt gtgtgtgtgg atgtgtgtgg ggtgtgggtg tcccttacgc ccttcctcct       60

ctccctcctc ctcctgctcc cccctccttt ccttctcctc ctcccccctc tcctctccct      120

cctcctggtc ctcatcgccc ctctcctcct cttcctcccc tctctcttcc tctccctgaa      180

ttttctcctc tcctctcagg tcagtccatg gtattccgct cccccctaga cctctattcc      240

tcccacttct tgttgccaaa cttcgccgat tctcaccacc gctccatact tctggcgagt      300

agcggcggcg ggaacggtgc gggaggcggc ggcggcgcgg gaggcggcag cggcggcggg      360

aacggtgcgg gaggcggcgg tgctggcgga gcaggcggcg gcggcggcgg cggctccagg      420

gcccccccgg aagagttgtc catgttccag ctgcccaccc tcaacttctc gccggagcag      480

gtggccagcg tctgtgagac gctggaggag acgggcgaca tcgagcggct gggccgcttc      540

ctctggtcgc tgcccgtggc ccccggggcg tgcgaggcca tcaacaaaca cgagtcgatc      600

ctgcgcgcgc gcgccgtggt cgccttccac acgggcaact tccgcgacct ctaccacatc      660

cttgagaacc acaagttcac caaggagtct cacggcaagc tgcaggccat gtggctcgag      720

gcgcactacc aggaggccga gaagctgcgc ggccgcccac tcggcccggt ggacaagtac      780

cgcgtgcgca agaagttccc gctgccacgc accatctggg acggcgagca gaagacgcat      840

tgcttcaagg agcggactcg gagcctgttg cgggagtggt acctacagga cccctacccc      900

aaccccagca agaaacgcga actggcgcag gccaccggcc tcactcccac acaagtaggc      960

aactggttta agaaccggcg gcagcgcgac cgcgccgcgg cggccaagaa caggctccag     1020

caccaggcca ttggaccgag cggcatgcgc tcgctggccg agcccggctg ccccacgcac     1080

ggctcggcag agtcgccgtc cacggcggcc agcccgacca ccagcgtgtc cagcctgacg     1140

gagcgcgcag acaccggcac ctccatcctc tcggtaacct ccagcgactc ggaatgtgat     1200

gtatgatagc caaggccgcc ctcctccctc tccttcccct cctcccccac tccttcccct     1260

ccgcctccta gccctcctcc tcttcctcct cttccttctc ctcctccatc cccagaacaa     1320

accgaaatca ggatacccaa ccatacacac atacaagtcc acacacactc ccaccccagc     1380

caaaaatata taaaaaacaa gaaaataaca aattaaccgc aaactatcaa caacccccaa     1440

ccaccatcta ccactacggc caccccaaag gaccccgacg ccaacagaca gtcaaacgct     1500

gatgttgcgg gcagaaaaca taaaagaggt gacaattgta tactttctag gacaagcacg     1560

gcttctcctt tcggttccca tggacccggc accccacctg catgacgatt tatttgtatc     1620

tgggaaaata ttctctctag ttaaaaatga tttaaagagt cgactataca aaaatcaatc     1680

accaccacga ggacaagagg gcaaaagcaa aacagacaaa aagaaaaaaa atcgccgtct     1740

ccgttccgaa tttgttaaaa aaaaaaaaaa aaaaaaaaaa aaggacaggg ggaaaaaaaa     1800

aaaaaaagaa ctcctggaga gggaaatagc aaatgtgtct tgccttttgt tgctctctct     1860

ctcttttttt ttctctcgct ctctttcttt ctcttcttct ctctgttttt aagtcaagta     1920

ttggtcaaaa aaatgcaatc ttctgttttt tgttcagcag acaatcattt tcttcgtaag     1980

cacctttttc tctccactct gtcactgcct gtgtgggtac tggttataaa tgtggaaaaa     2040

gaatagttat gactgtaaca gatttttatt tttatttcaa aattttatat gaattatgta     2100

tatcttaatg atcggtcatt ttcccagttt gtaatatatg tgtagaaatt gcctgtatat     2160

gatattgctt tttctcctct ccctttctct ttctctcctc tccctctctc tgtctttctc     2220

cccgctcaac tgtctctttt ctttttgggg ttctcctccc actcggtgct cctggtgtcg     2280

acttggcagt caaggagagg catggtggcc tgggttagga agagggaccc tgtcgctagc     2340

aaaagcggag agtgagattg tagtattctt atgcaaaagc tatttccagt atttcttagc     2400

agcttcagag gtatctctca ctccctgtag ggcgctttta ctgttatctt aaactgcgtg     2460

tttatctata tgtaaaaact ttctaaagca aatacagtat tctccatttt cttatcactc     2520

ccaaaaaaaa aaa                                                        2533


<210>  384
<211>  2728
<212>  DNA
<213>  homo sapiens

<400>  384
cacgcccctg ggcggtgcgc gcgggcggtg ggtaggccgg gcaggctcac gtgatgcggg       60

ccccgcggcc cgccatataa acccgcgcgc ccgccaggcg ctgcggccgt cccgggccgt      120

gactcctcct ttcccccgcc ccgcctccgt tcggagagcc ggcgggcggg cgcctctcgg      180

ccaggaagcg cctcttggac gcgtgtgacc gatgcccaga ttgcacgacc acttctggag      240

ctgctcctgt gcgcacagcg cgaggcgccg aggccccccg cgagccagcg ccgcggggct      300

ggcggccaag gttggggaga tgatcaacgt ttccgtgtcc gggccctccc tgctggcggc      360

ccacggtgcc ccggacgctg accccgcgcc caggggccgc agtgctgcga tgagcggccc      420

cgagcccggc agcccctacc ccaacacctg gcatcatcgc ctgttgcaga ggagcctcgt      480

gctcttctcg gttggggtgg tcctagccct ggtgctcaac ctgctgcaga tccagaggaa      540

tgtcactctc ttccccgagg aggtgatcgc caccatcttt tcctccgcct ggtgggtccc      600

tccctgctgc gggacagcag ctggtataca tccccagatt tcctctatat tcgttcttgg      660

ctcccttgta tatttttctc aggaggcgtc acggtgggga acataggacg acagttagct      720

atgggtgttc ctgaaaagcc ccatagtgat tgagtcttca aaaccaccga ttctgagagc      780

aaggaagatt ttggaagaaa atctgactgt ggattatgac aaagattatc ttttttctta      840

agtaatctat ttagatcggg ctgactgtac aaatgactcc tggaaaaaac tcttcaccta      900

gtctagaata gggaggtgga gaatgatgac ttaccctgaa gtcttccctt gactgcccgc      960

actggcgcct gtctgtgccc tggagcattc tgcccaggct acgtgggttc aggcaggtgg     1020

cagcttccca agtattcgat ttcattcatg tgattaaaac aagttgccat atttcaaagc     1080

cttgaactaa gactcaatta ccaacccgca gttttgtgtc agtgcccaaa ggaggtaggt     1140

tgatggtgct taacaaacat gaagtatggt gtaataggaa taatatttat ccaaaagatt     1200

tttaaaaata gggctgtgtt taaaaaaaaa aacaaaacaa gaaaagcagc agtgattata     1260

gagaggtcac actctaagtg gggtcgcggc gtggccacgc ttcacggtca cgctcgtccg     1320

tcctgcagtg gcgtgtttac atggtcacac gtgtgtgtat caccagtggg tcaactgctt     1380

gtcattcctc ccgtggcagt ttgtgtagac aatcttactg agcaaaaggc aatgaaaagt     1440

cttggttccc acactgcgat atattggaat tttcacctca gtttatgaag tttatttcga     1500

aatccatagt catctaagaa tgaatacctg tctgccatgt atttcaatct tagtgagcca     1560

aaattgtttg tttgttacta cagaatagag atgactgttt tttgccacag ccctatggaa     1620

tttgcaatct gtgattgcct tgtaaaaagg agagtgcata tggcactgca ttaaacgtgt     1680

ggtgtttcta gtcaatgata ttggtgagca caatgtattc atttaatggc atagaccata     1740

ccagacctaa tttgcaagta ttgggtctta aacttcaagt gcaatgtata tgaaaaccaa     1800

tctgagcctt gtatctctta aatatttatt ttttttaacg tgtgagatgt tcgagagaag     1860

gttctccatt catttcagtg ctgcctggag gaaactcggc aatgatttct ttcagttgtg     1920

aagttccttt cgtgttacac cctccactga accctcaacc ttcgaaatac tccagttttg     1980

tgggtttggt catttttact tataaattta cctttttgta ttttgcaatt tacatgtgtt     2040

tggtttgttt taaattctgt gaaagtggct tgattaaaag actcctttta aatggaagcc     2100

accagtcagc agaatggaag cttagaggaa cttgcctgtg agcgctggtc tttgtgtttg     2160

gttttgtgat gtaacgatct ttgctggggt tttttgcttt gttttgaggg aaatgtcttg     2220

gagtaaattt taagttcctg gagttaattt gttttacagg aattttgttt tttaaaaaaa     2280

taggatcatt ctgaactttg gaatgacccc cttatatatt ttctgaaaat gaaaacagtt     2340

acatgaaaaa aatttccaat gaagatgtca gcattttatg aaaaaccaga agttattaga     2400

tgaaagcagc gagtgaatct ttaaaacaga cttgatcacg cacacacaat aagtctttct     2460

ctccgaaacc ggaagtaaat ctatatctgt tagaaataat gtagccaaaa gaatgtaaat     2520

ttgaggattt ttttgccaat agtttataga aaatatatga accaaagtga tttgagtttg     2580

taaaaatgta aaatagtatg aacaaaattt gcactctacc agatttgaac atctagtgag     2640

gttcacattc atactaagtt ttcaacattg tgttcttttt gcattcattt tttactttta     2700

ttaaaggttc aaaaccaaaa aaaaaaaa                                        2728


<210>  385
<211>  3020
<212>  DNA
<213>  homo sapiens

<400>  385
cacgcccctg ggcggtgcgc gcgggcggtg ggtaggccgg gcaggctcac gtgatgcggg       60

ccccgcggcc cgccatataa acccgcgcgc ccgccaggcg ctgcggccgt cccgggccgt      120

gactcctcct ttcccccgcc ccgcctccgt tcggagagcc ggcgggcggg cgcctctcgg      180

ccaggaagcg cctcttggac gcgtgtgacc gatgcccaga ttgcacgacc acttctggag      240

ctgctcctgt gcgcacagcg cgaggcgccg aggccccccg cgagccagcg ccgcggggct      300

ggcggccaag gttggggaga tgatcaacgt ttccgtgtcc gggccctccc tgctggcggc      360

ccacggtgcc ccggacgctg accccgcgcc caggggccgc agtgctgcga tgagcggccc      420

cgagcccggc agcccctacc ccaacacctg gcatcatcgc ctgttgcaga ggagcctcgt      480

gctcttctcg gttggggtgg tcctagccct ggtgctcaac ctgctgcaga tccagaggaa      540

tgtcactctc ttccccgagg aggtgatcgc caccatcttt tcctccgcct ggtgggtccc      600

tccctgctgc gggacagcag ctgctgttgt tggcctactg tacccctgta tcgacagtca      660

cctcggagaa ccccacaaat ttaagagaga atgggccagt gtcatgcgct gcatagcagt      720

ttttgttggc attaaccacg ccagtgctaa attggatttt gccaataatg tccagctgtc      780

cttgacttta gcagccctat ctttgggcct ttggtggaca tttgatcgtt ccagaagtgg      840

ccttgggctg gggatcacca tagcttttct agctacgctg atcacgcagt ttctcgtgta      900

taatggtgtc tatcagtata catccccaga tttcctctat attcgttctt ggctcccttg      960

tatatttttc tcaggaggcg tcacggtggg gaacatagga cgacagttag ctatgggtgt     1020

tcctgaaaag ccccatagtg attgagtctt caaaaccacc gattctgaga gcaaggaaga     1080

ttttggaaga aaatctgact gtggattatg acaaagatta tcttttttct taagtaatct     1140

atttagatcg ggctgactgt acaaatgact cctggaaaaa actcttcacc tagtctagaa     1200

tagggaggtg gagaatgatg acttaccctg aagtcttccc ttgactgccc gcactggcgc     1260

ctgtctgtgc cctggagcat tctgcccagg ctacgtgggt tcaggcaggt ggcagcttcc     1320

caagtattcg atttcattca tgtgattaaa acaagttgcc atatttcaaa gccttgaact     1380

aagactcaat taccaacccg cagttttgtg tcagtgccca aaggaggtag gttgatggtg     1440

cttaacaaac atgaagtatg gtgtaatagg aataatattt atccaaaaga tttttaaaaa     1500

tagggctgtg tttaaaaaaa aaaacaaaac aagaaaagca gcagtgatta tagagaggtc     1560

acactctaag tggggtcgcg gcgtggccac gcttcacggt cacgctcgtc cgtcctgcag     1620

tggcgtgttt acatggtcac acgtgtgtgt atcaccagtg ggtcaactgc ttgtcattcc     1680

tcccgtggca gtttgtgtag acaatcttac tgagcaaaag gcaatgaaaa gtcttggttc     1740

ccacactgcg atatattgga attttcacct cagtttatga agtttatttc gaaatccata     1800

gtcatctaag aatgaatacc tgtctgccat gtatttcaat cttagtgagc caaaattgtt     1860

tgtttgttac tacagaatag agatgactgt tttttgccac agccctatgg aatttgcaat     1920

ctgtgattgc cttgtaaaaa ggagagtgca tatggcactg cattaaacgt gtggtgtttc     1980

tagtcaatga tattggtgag cacaatgtat tcatttaatg gcatagacca taccagacct     2040

aatttgcaag tattgggtct taaacttcaa gtgcaatgta tatgaaaacc aatctgagcc     2100

ttgtatctct taaatattta ttttttttaa cgtgtgagat gttcgagaga aggttctcca     2160

ttcatttcag tgctgcctgg aggaaactcg gcaatgattt ctttcagttg tgaagttcct     2220

ttcgtgttac accctccact gaaccctcaa ccttcgaaat actccagttt tgtgggtttg     2280

gtcattttta cttataaatt tacctttttg tattttgcaa tttacatgtg tttggtttgt     2340

tttaaattct gtgaaagtgg cttgattaaa agactccttt taaatggaag ccaccagtca     2400

gcagaatgga agcttagagg aacttgcctg tgagcgctgg tctttgtgtt tggttttgtg     2460

atgtaacgat ctttgctggg gttttttgct ttgttttgag ggaaatgtct tggagtaaat     2520

tttaagttcc tggagttaat ttgttttaca ggaattttgt tttttaaaaa aataggatca     2580

ttctgaactt tggaatgacc cccttatata ttttctgaaa atgaaaacag ttacatgaaa     2640

aaaatttcca atgaagatgt cagcatttta tgaaaaacca gaagttatta gatgaaagca     2700

gcgagtgaat ctttaaaaca gacttgatca cgcacacaca ataagtcttt ctctccgaaa     2760

ccggaagtaa atctatatct gttagaaata atgtagccaa aagaatgtaa atttgaggat     2820

ttttttgcca atagtttata gaaaatatat gaaccaaagt gatttgagtt tgtaaaaatg     2880

taaaatagta tgaacaaaat ttgcactcta ccagatttga acatctagtg aggttcacat     2940

tcatactaag ttttcaacat tgtgttcttt ttgcattcat tttttacttt tattaaaggt     3000

tcaaaaccaa aaaaaaaaaa                                                 3020


<210>  386
<211>  2635
<212>  DNA
<213>  homo sapiens

<400>  386
cacgcccctg ggcggtgcgc gcgggcggtg ggtaggccgg gcaggctcac gtgatgcggg       60

ccccgcggcc cgccatataa acccgcgcgc ccgccaggcg ctgcggccgt cccgggccgt      120

gactcctcct ttcccccgcc ccgcctccgt tcggagagcc ggcgggcggg cgcctctcgg      180

ccaggaagcg cctcttggac gcgtgtgacc gatgcccaga ttgcacgacc acttctggag      240

ctgctcctgt gcgcacagcg cgaggcgccg aggccccccg cgagccagcg ccaaattgga      300

ttttgccaat aatgtccagc tgtccttgac tttagcagcc ctatctttgg gcctttggtg      360

gacatttgat cgttccagaa gtggccttgg gctggggatc accatagctt ttctagctac      420

gctgatcacg cagtttctcg tgtataatgg tgtctatcag tatacatccc cagatttcct      480

ctatattcgt tcttggctcc cttgtatatt tttctcagga ggcgtcacgg tggggaacat      540

aggacgacag ttagctatgc tgataccctt ctgtgaggag ttgaatttga agaccacttg      600

gctgtttcac aaaaccagaa gtaattacag ggtgttcctg aaaagcccca tagtgattga      660

gtcttcaaaa ccaccgattc tgagagcaag gaagattttg gaagaaaatc tgactgtgga      720

ttatgacaaa gattatcttt tttcttaagt aatctattta gatcgggctg actgtacaaa      780

tgactcctgg aaaaaactct tcacctagtc tagaataggg aggtggagaa tgatgactta      840

ccctgaagtc ttcccttgac tgcccgcact ggcgcctgtc tgtgccctgg agcattctgc      900

ccaggctacg tgggttcagg caggtggcag cttcccaagt attcgatttc attcatgtga      960

ttaaaacaag ttgccatatt tcaaagcctt gaactaagac tcaattacca acccgcagtt     1020

ttgtgtcagt gcccaaagga ggtaggttga tggtgcttaa caaacatgaa gtatggtgta     1080

ataggaataa tatttatcca aaagattttt aaaaataggg ctgtgtttaa aaaaaaaaac     1140

aaaacaagaa aagcagcagt gattatagag aggtcacact ctaagtgggg tcgcggcgtg     1200

gccacgcttc acggtcacgc tcgtccgtcc tgcagtggcg tgtttacatg gtcacacgtg     1260

tgtgtatcac cagtgggtca actgcttgtc attcctcccg tggcagtttg tgtagacaat     1320

cttactgagc aaaaggcaat gaaaagtctt ggttcccaca ctgcgatata ttggaatttt     1380

cacctcagtt tatgaagttt atttcgaaat ccatagtcat ctaagaatga atacctgtct     1440

gccatgtatt tcaatcttag tgagccaaaa ttgtttgttt gttactacag aatagagatg     1500

actgtttttt gccacagccc tatggaattt gcaatctgtg attgccttgt aaaaaggaga     1560

gtgcatatgg cactgcatta aacgtgtggt gtttctagtc aatgatattg gtgagcacaa     1620

tgtattcatt taatggcata gaccatacca gacctaattt gcaagtattg ggtcttaaac     1680

ttcaagtgca atgtatatga aaaccaatct gagccttgta tctcttaaat atttattttt     1740

tttaacgtgt gagatgttcg agagaaggtt ctccattcat ttcagtgctg cctggaggaa     1800

actcggcaat gatttctttc agttgtgaag ttcctttcgt gttacaccct ccactgaacc     1860

ctcaaccttc gaaatactcc agttttgtgg gtttggtcat ttttacttat aaatttacct     1920

ttttgtattt tgcaatttac atgtgtttgg tttgttttaa attctgtgaa agtggcttga     1980

ttaaaagact ccttttaaat ggaagccacc agtcagcaga atggaagctt agaggaactt     2040

gcctgtgagc gctggtcttt gtgtttggtt ttgtgatgta acgatctttg ctggggtttt     2100

ttgctttgtt ttgagggaaa tgtcttggag taaattttaa gttcctggag ttaatttgtt     2160

ttacaggaat tttgtttttt aaaaaaatag gatcattctg aactttggaa tgaccccctt     2220

atatattttc tgaaaatgaa aacagttaca tgaaaaaaat ttccaatgaa gatgtcagca     2280

ttttatgaaa aaccagaagt tattagatga aagcagcgag tgaatcttta aaacagactt     2340

gatcacgcac acacaataag tctttctctc cgaaaccgga agtaaatcta tatctgttag     2400

aaataatgta gccaaaagaa tgtaaatttg aggatttttt tgccaatagt ttatagaaaa     2460

tatatgaacc aaagtgattt gagtttgtaa aaatgtaaaa tagtatgaac aaaatttgca     2520

ctctaccaga tttgaacatc tagtgaggtt cacattcata ctaagttttc aacattgtgt     2580

tctttttgca ttcatttttt acttttatta aaggttcaaa accaaaaaaa aaaaa          2635


<210>  387
<211>  2728
<212>  DNA
<213>  homo sapiens

<400>  387
cacgcccctg ggcggtgcgc gcgggcggtg ggtaggccgg gcaggctcac gtgatgcggg       60

ccccgcggcc cgccatataa acccgcgcgc ccgccaggcg ctgcggccgt cccgggccgt      120

gactcctcct ttcccccgcc ccgcctccgt tcggagagcc ggcgggcggg cgcctctcgg      180

ccaggaagcg cctcttggac gcgtgtgacc gatgcccaga ttgcacgacc acttctggag      240

ctgctcctgt gcgcacagcg cgaggcgccg aggccccccg cgagccagcg ccgcggggct      300

ggcggccaag gttggggaga tgatcaacgt ttccgtgtcc gggccctccc tgctggcggc      360

ccacggtgcc ccggacgctg accccgcgcc caggggccgc agtgctgcga tgagcggccc      420

cgagcccggc agcccctacc ccaacacctg gcatcatcgc ctgttgcaga ggagcctcgt      480

gctcttctcg gttggggtgg tcctagccct ggtgctcaac ctgctgcaga tccagaggaa      540

tgtcactctc ttccccgagg aggtgatcgc caccatcttt tcctccgcct ggtgggtccc      600

tccctgctgc gggacagcag ctggtataca tccccagatt tcctctatat tcgttcttgg      660

ctcccttgta tatttttctc aggaggcgtc acggtgggga acataggacg acagttagct      720

atgggtgttc ctgaaaagcc ccatagtgat tgagtcttca aaaccaccga ttctgagagc      780

aaggaagatt ttggaagaaa atctgactgt ggattatgac aaagattatc ttttttctta      840

agtaatctat ttagatcggg ctgactgtac aaatgactcc tggaaaaaac tcttcaccta      900

gtctagaata gggaggtgga gaatgatgac ttaccctgaa gtcttccctt gactgcccgc      960

actggcgcct gtctgtgccc tggagcattc tgcccaggct acgtgggttc aggcaggtgg     1020

cagcttccca agtattcgat ttcattcatg tgattaaaac aagttgccat atttcaaagc     1080

cttgaactaa gactcaatta ccaacccgca gttttgtgtc agtgcccaaa ggaggtaggt     1140

tgatggtgct taacaaacat gaagtatggt gtaataggaa taatatttat ccaaaagatt     1200

tttaaaaata gggctgtgtt taaaaaaaaa aacaaaacaa gaaaagcagc agtgattata     1260

gagaggtcac actctaagtg gggtcgcggc gtggccacgc ttcacggtca cgctcgtccg     1320

tcctgcagtg gcgtgtttac atggtcacac gtgtgtgtat caccagtggg tcaactgctt     1380

gtcattcctc ccgtggcagt ttgtgtagac aatcttactg agcaaaaggc aatgaaaagt     1440

cttggttccc acactgcgat atattggaat tttcacctca gtttatgaag tttatttcga     1500

aatccatagt catctaagaa tgaatacctg tctgccatgt atttcaatct tagtgagcca     1560

aaattgtttg tttgttacta cagaatagag atgactgttt tttgccacag ccctatggaa     1620

tttgcaatct gtgattgcct tgtaaaaagg agagtgcata tggcactgca ttaaacgtgt     1680

ggtgtttcta gtcaatgata ttggtgagca caatgtattc atttaatggc atagaccata     1740

ccagacctaa tttgcaagta ttgggtctta aacttcaagt gcaatgtata tgaaaaccaa     1800

tctgagcctt gtatctctta aatatttatt ttttttaacg tgtgagatgt tcgagagaag     1860

gttctccatt catttcagtg ctgcctggag gaaactcggc aatgatttct ttcagttgtg     1920

aagttccttt cgtgttacac cctccactga accctcaacc ttcgaaatac tccagttttg     1980

tgggtttggt catttttact tataaattta cctttttgta ttttgcaatt tacatgtgtt     2040

tggtttgttt taaattctgt gaaagtggct tgattaaaag actcctttta aatggaagcc     2100

accagtcagc agaatggaag cttagaggaa cttgcctgtg agcgctggtc tttgtgtttg     2160

gttttgtgat gtaacgatct ttgctggggt tttttgcttt gttttgaggg aaatgtcttg     2220

gagtaaattt taagttcctg gagttaattt gttttacagg aattttgttt tttaaaaaaa     2280

taggatcatt ctgaactttg gaatgacccc cttatatatt ttctgaaaat gaaaacagtt     2340

acatgaaaaa aatttccaat gaagatgtca gcattttatg aaaaaccaga agttattaga     2400

tgaaagcagc gagtgaatct ttaaaacaga cttgatcacg cacacacaat aagtctttct     2460

ctccgaaacc ggaagtaaat ctatatctgt tagaaataat gtagccaaaa gaatgtaaat     2520

ttgaggattt ttttgccaat agtttataga aaatatatga accaaagtga tttgagtttg     2580

taaaaatgta aaatagtatg aacaaaattt gcactctacc agatttgaac atctagtgag     2640

gttcacattc atactaagtt ttcaacattg tgttcttttt gcattcattt tttactttta     2700

ttaaaggttc aaaaccaaaa aaaaaaaa                                        2728


<210>  388
<211>  5361
<212>  DNA
<213>  homo sapiens

<400>  388
tttctccttc cctccacggg ccgggtgaga aagtagccgg gggctatccc gacccggcgg       60

ttcttgggga gggggccgaa caagaaaagg gaggagatgg agataacttc cccggattta      120

gcttttttgt ctttgttttt gttctcacca cttccatcgg atgactggag agtaaaaggg      180

aacccggagc ggggtggcga gcagcgcttt gagaaaatgc aggagtgtgt ttggagacgc      240

gtaaagttgc ctttcaagct ctggcctccg ggcacgcgat gctccgcggc gggctgactc      300

agggctgcct tgggcctccc tgccaccctc ctggaaatga tgcaagtcct gactgtcacc      360

tggatccctg cagcccagcc tggaatgcgt ctggattagg ggaaagacga gaaacgacac      420

tccaggtgtt gcacggccca ccaaagcggg aagatagggc agttgctcag accaaatact      480

gtatctagtg cttctgctcc tatcttcaat cgtggggttc tttttaatgc aaagtgtcac      540

aaggccagga attcccatgt gtgctcagtt ggcccacagc atcattgtgc ctaggaaact      600

gcttcaattt atcaagtcct ctgggctggg aatctcactg aattccaaac ggcggaaaga      660

ggaaactttc ccaacccgat gtgggtgtga cgcgagccag gggccccagg gacactgtcc      720

cagagcacac cgtccccctt taacagcaac tggagcttgg attcgctctt atattgtaca      780

gtcctttcga ccattgccct ggagcacccg cacacgcgca cgcatctccg gccgcgctca      840

cacacactca tacacacgca cgcaaacgcg tggccgccgc caggtcggca actttgtccg      900

gcgctcccag cggcgctcgg cttcctcctg tagtagttga gcgcaggccc cgcctcccgg      960

ccgtgttgtc aaaagggccg gggtctcgga ttggtccagc cgccgggaca acacctgctc     1020

gactccttca ttcaagtgac accagagctt ccagggatat ttgaggcacc atccctgcca     1080

ttgccgggca ctcgcggcgc tgctaacggc ctggtcacat gctctccgga gagctacggg     1140

agggcgctgg gtaacctcta tccgagccgc ggccgcgagg aggagggaaa aggcgagcaa     1200

aaaggaagag tgggaggagg aggggaagcg gcgaaggagg aagaggagga ggaggaagag     1260

gggagcacaa aggatccagg tctcccgacg ggaggttaat accaagaacc atgtgtgccg     1320

agcggctggg ccagttcatg accctggctt tggtgttggc cacctttgac ccggcgcggg     1380

ggaccgacgc caccaaccca cccgagggtc cccaagacag gagctcccag cagaaaggcc     1440

gcctgtccct gcagaataca gcggagatcc agcactgttt ggtcaacgct ggcgatgtgg     1500

ggtgtggcgt gtttgaatgt ttcgagaaca actcttgtga gattcggggc ttacatggga     1560

tttgcatgac ttttctgcac aacgctggaa aatttgatgc ccagggcaag tcattcatca     1620

aagacgcctt gaaatgtaag gcccacgctc tgcggcacag gttcggctgc ataagccgga     1680

agtgcccggc catcagggaa atggtgtccc agttgcagcg ggaatgctac ctcaagcacg     1740

acctgtgcgc ggctgcccag gagaacaccc gggtgatagt ggagatgatc catttcaagg     1800

acttgctgct gcacgaaccc tacgtggacc tcgtgaactt gctgctgacc tgtggggagg     1860

aggtgaagga ggccatcacc cacagcgtgc aggttcagtg tgagcagaac tggggaagcc     1920

tgtgctccat cttgagcttc tgcacctcgg ccatccagaa gcctcccacg gcgccccccg     1980

agcgccagcc ccaggtggac agaaccaagc tctccagggc ccaccacggg gaagcaggac     2040

atcacctccc agagcccagc agtagggaga ctggccgagg tgccaagggt gagcgaggta     2100

gcaagagcca cccaaacgcc catgcccgag gcagagtcgg gggccttggg gctcagggac     2160

cttccggaag cagcgagtgg gaagacgaac agtctgagta ttctgatatc cggaggtgaa     2220

atgaaaggcc tggccacgaa atctttcctc cacgccgtcc attttcttat ctatggacat     2280

tccaaaacat ttaccattag agagggggga tgtcacacgc aggattctgt ggggactgtg     2340

gacttcatcg aggtgtgtgt tcgcggaacg gacaggtgag atggagaccc ctggggccgt     2400

ggggtctcag gggtgcctgg tgaattctgc acttacacgt actcaaggga gcgcgcccgc     2460

gttatcctcg tacctttgtc ttctttccat ctgtggagtc agtgggtgtc ggccgctctg     2520

ttgtggggga ggtgaaccag ggaggggcag ggcaaggcag ggcccccaga gctgggccac     2580

acagtgggtg ctgggcctcg ccccgaagct tctggtgcag cagcctctgg tgctgtctcc     2640

gcggaagtca gggcggctgg attccaggac aggagtgaat gtaaaaataa atatcgctta     2700

gaatgcagga gaagggtgga gaggaggcag gggccgaggg ggtgcttggt gccaaactga     2760

aattcagttt cttgtgtggg gccttgcggt tcagagctct tggcgagggt ggagggagga     2820

gtgtcatttc tatgtgtaat ttctgagcca ttgtactgtc tgggctgggg gggacactgt     2880

ccaagggagt ggcccctatg agtttatatt ttaaccactg cttcaaatct cgatttcact     2940

ttttttattt atccagttat atctacatat ctgtcatcta aataaatggc tttcaaacaa     3000

agcaactggg tcattaaaac cagctcaaag ggggtttaaa aaaaaaaaac cagcccatcc     3060

tttgaggctg atttttcttt tttttaagtt ctattttaaa agctatcaaa cagcgacata     3120

gccatacatc tgactgcctg acatggactc ctgcccactt gggggaaacc ttatacccag     3180

aggaaaatac acacctgggg agtacatttg acaaatttcc cttaggattt cgttatctca     3240

ccttgaccct cagccaagat tggtaaagct gcgtcctggc gattccagga gacccagctg     3300

gaaacctggc ttctccatgt gaggggatgg gaaaggaaag aagagaatga agactactta     3360

gtaattccca tcaggaaatg ctgacctttt acataaaatc aaggagactg ctgaaaatct     3420

ctaagggaca ggattttcca gatcctaatt ggaaatttag caataaggag aggagtccaa     3480

ggggacaaat aaaggcagag agaagagaca gaactaaaaa tacgaggaaa ggagagtgag     3540

gattttcatt aaaagtctca gcagtgggtt tcttgggtta tttaaaacat cacctaaata     3600

ggccttttct tcctaattgg ccatcaaatt aaagcctatc ctttctcaag caggagctgg     3660

tattgtaggg agtggccggg tattctgggc tgggctcttc tggagtaggg ggtcagcaaa     3720

cattgtctgc aaagggccag atactgaatc cagtactttc agtttggcga gccgtgaggt     3780

ctctgtcgaa actactcaac tctgccgtcc tagcacaaaa gcagccatag acaacacaca     3840

aacgagaggg cttggctccc ttccaggaag atttatttaa caggctccca gctgaatttc     3900

actcacagga cacagtttac tgatctctgt tctagtgagt gggtcaaaaa gcatatgcat     3960

ccttatccgt caactcatca gctcttcctc aaggcaacct gaggccagac accaagaaac     4020

caagcgtatc tgctctaaaa tgacttgttc ctggggaatg ccttcaacca aaacacagct     4080

agtatttcta tgccccaaat ccaatcccag tctttcatga tccatgccgg cggttgggtg     4140

gggaggggaa tcattggttg ggggaaggga ggaaacccca cctccagccc ccgccaccgg     4200

gctccctggg cacccagcaa gatctggggc tgcagagaac agaagagctg gtgcacttaa     4260

tccagctctg cccttggggg gaggaggacc tgtgtgtcag gctctgccat gggaacgagt     4320

gtaaaccgtg gctgtctcct gcagtgagcc accgcggcag gcacgttgac tgttttactg     4380

acatcactca aaagctaaag caataacatt ctcctgcgtt gctgagtcag ctgttcattt     4440

gtccgccagc tcctggactg gatgtgtgaa aggcatcaca tttccatttt cctccgtgta     4500

aatgttttat gtgttcgcct actgatccca ttcgttgctt ctattgtaaa tatttgtcat     4560

ttgtatttat tatctctgtg ttttccccct aaggcataaa atggtttact gtgttcattt     4620

gaacccattt actgatctct gttgtatatt tttcatgcca ctgctttgtt ttctcctcag     4680

aagtcgggta gatagcattt ctatcccatc cctcacgtta ttggaagcat gcaacagtat     4740

ttattgctca gggtcttctg cttaaaactg aggaaggtcc acattcctgc aagcattgat     4800

tgagacattt gcacaatcta aaatgtaagc aaagtagtca ttaaaaatac accctctact     4860

tgggctttat actgcataca aatttactca tgagccttcc tttgaggaag gatgtggatc     4920

tccaaataaa gatttagtgt ttattttgag ctctgcatct taacaagatg atctgaacac     4980

ctctcctttg tatcaataaa tagccctgtt attctgaagt gagaggacca agtatagtaa     5040

aatgctgaca tctaaaacta aataaataga aaacaccagg ccagaactat agtcatactc     5100

acacaaaggg agaaatttaa actcgaacca agcaaaaggc ttcacggaaa tagcatggaa     5160

aaacaatgct tccagtggcc acttcctaag gaggaacaac cccgtctgat ctcagaattg     5220

gcaccacgtg agcttgctaa gtgataatat ctgtttctac tacggattta ggcaacagga     5280

cctgtacatt gtcacattgc attatttttc ttcaagcgtt aataaaagtt ttaaataaat     5340

ggcaaaaaaa aaaaaaaaaa a                                               5361


<210>  389
<211>  4678
<212>  DNA
<213>  homo sapiens

<400>  389
gcacacagag cagcataaag cccagttgct ttgggaagtg tttgggacca gatggattgt       60

agggagtagg gtacaataca gtctgttctc ctccagctcc ttctttctgc aacatgggga      120

agaacaaact ccttcatcca agtctggttc ttctcctctt ggtcctcctg cccacagacg      180

cctcagtctc tggaaaaccg cagtatatgg ttctggtccc ctccctgctc cacactgaga      240

ccactgagaa gggctgtgtc cttctgagct acctgaatga gacagtgact gtaagtgctt      300

ccttggagtc tgtcagggga aacaggagcc tcttcactga cctggaggcg gagaatgacg      360

tactccactg tgtcgccttc gctgtcccaa agtcttcatc caatgaggag gtaatgttcc      420

tcactgtcca agtgaaagga ccaacccaag aatttaagaa gcggaccaca gtgatggtta      480

agaacgagga cagtctggtc tttgtccaga cagacaaatc aatctacaaa ccagggcaga      540

cagtgaaatt tcgtgttgtc tccatggatg aaaactttca ccccctgaat gagttgattc      600

cactagtata cattcaggat cccaaaggaa atcgcatcgc acaatggcag agtttccagt      660

tagagggtgg cctcaagcaa ttttcttttc ccctctcatc agagcccttc cagggctcct      720

acaaggtggt ggtacagaag aaatcaggtg gaaggacaga gcaccctttc accgtggagg      780

aatttgttct tcccaagttt gaagtacaag taacagtgcc aaagataatc accatcttgg      840

aagaagagat gaatgtatca gtgtgtggcc tatacacata tgggaagcct gtccctggac      900

atgtgactgt gagcatttgc agaaagtata gtgacgcttc cgactgccac ggtgaagatt      960

cacaggcttt ctgtgagaaa ttcagtggac agctaaacag ccatggctgc ttctatcagc     1020

aagtaaaaac caaggtcttc cagctgaaga ggaaggagta tgaaatgaaa cttcacactg     1080

aggcccagat ccaagaagaa ggaacagtgg tggaattgac tggaaggcag tccagtgaaa     1140

tcacaagaac cataaccaaa ctctcatttg tgaaagtgga ctcacacttt cgacagggaa     1200

ttcccttctt tgggcaggtg cgcctagtag atgggaaagg cgtccctata ccaaataaag     1260

tcatattcat cagaggaaat gaagcaaact attactccaa tgctaccacg gatgagcatg     1320

gccttgtaca gttctctatc aacaccacca atgttatggg tacctctctt actgttaggg     1380

tcaattacaa ggatcgtagt ccctgttacg gctaccagtg ggtgtcagaa gaacacgaag     1440

aggcacatca cactgcttat cttgtgttct ccccaagcaa gagctttgtc caccttgagc     1500

ccatgtctca tgaactaccc tgtggccata ctcagacagt ccaggcacat tatattctga     1560

atggaggcac cctgctgggg ctgaagaagc tctccttcta ttatctgata atggcaaagg     1620

gaggcattgt ccgaactggg actcatggac tgcttgtgaa gcaggaagac atgaagggcc     1680

atttttccat ctcaatccct gtgaagtcag acattgctcc tgtcgctcgg ttgctcatct     1740

atgctgtttt acctaccggg gacgtgattg gggattctgc aaaatatgat gttgaaaatt     1800

gtctggccaa caaggtggat ttgagcttca gcccatcaca aagtctccca gcctcacacg     1860

cccacctgcg agtcacagcg gctcctcagt ccgtctgcgc cctccgtgct gtggaccaaa     1920

gcgtgctgct catgaagcct gatgctgagc tctcggcgtc ctcggtttac aacctgctac     1980

cagaaaagga cctcactggc ttccctgggc ctttgaatga ccaggacgat gaagactgca     2040

tcaatcgtca taatgtctat attaatggaa tcacatatac tccagtatca agtacaaatg     2100

aaaaggatat gtacagcttc ctagaggaca tgggcttaaa ggcattcacc aactcaaaga     2160

ttcgtaaacc caaaatgtgt ccacagcttc aacagtatga aatgcatgga cctgaaggtc     2220

tacgtgtagg tttttatgag tcagatgtaa tgggaagagg ccatgcacgc ctggtgcatg     2280

ttgaagagcc tcacacggag accgtacgaa agtacttccc tgagacatgg atctgggatt     2340

tggtggtggt aaactcagca ggtgtggctg aggtaggagt aacagtccct gacaccatca     2400

ccgagtggaa ggcaggggcc ttctgcctgt ctgaagatgc tggacttggt atctcttcca     2460

ctgcctctct ccgagccttc cagcccttct ttgtggagct cacaatgcct tactctgtga     2520

ttcgtggaga ggccttcaca ctcaaggcca cggtcctaaa ctaccttccc aaatgcatcc     2580

gggtcagtgt gcagctggaa gcctctcccg ccttcctagc tgtcccagtg gagaaggaac     2640

aagcgcctca ctgcatctgt gcaaacgggc ggcaaactgt gtcctgggca gtaaccccaa     2700

agtcattagg aaatgtgaat ttcactgtga gcgcagaggc actagagtct caagagctgt     2760

gtgggactga ggtgccttca gttcctgaac acggaaggaa agacacagtc atcaagcctc     2820

tgttggttga acctgaagga ctagagaagg aaacaacatt caactcccta ctttgtccat     2880

caggtggtga ggtttctgaa gaattatccc tgaaactgcc accaaatgtg gtagaagaat     2940

ctgcccgagc ttctgtctca gttttgggag acatattagg ctctgccatg caaaacacac     3000

aaaatcttct ccagatgccc tatggctgtg gagagcagaa tatggtcctc tttgctccta     3060

acatctatgt actggattat ctaaatgaaa cacagcagct tactccagag atcaagtcca     3120

aggccattgg ctatctcaac actggttacc agagacagtt gaactacaaa cactatgatg     3180

gctcctacag cacctttggg gagcgatatg gcaggaacca gggcaacacc tggctcacag     3240

cctttgttct gaagactttt gcccaagctc gagcctacat cttcatcgat gaagcacaca     3300

ttacccaagc cctcatatgg ctctcccaga ggcagaagga caatggctgt ttcaggagct     3360

ctgggtcact gctcaacaat gccataaagg gaggagtaga agatgaagtg accctctccg     3420

cctatatcac catcgccctt ctggagattc ctctcacagt cactcaccct gttgtccgca     3480

atgccctgtt ttgcctggag tcagcctgga agacagcaca agaaggggac catggcagcc     3540

atgtatatac caaagcactg ctggcctatg cttttgccct ggcaggtaac caggacaaga     3600

ggaaggaagt actcaagtca cttaatgagg aagctgtgaa gaaagacaac tctgtccatt     3660

gggagcgccc tcagaaaccc aaggcaccag tggggcattt ttacgaaccc caggctccct     3720

ctgctgaggt ggagatgaca tcctatgtgc tcctcgctta tctcacggcc cagccagccc     3780

caacctcgga ggacctgacc tctgcaacca acatcgtgaa gtggatcacg aagcagcaga     3840

atgcccaggg cggtttctcc tccacccagg acacagtggt ggctctccat gctctgtcca     3900

aatatggagc agccacattt accaggactg ggaaggctgc acaggtgact atccagtctt     3960

cagggacatt ttccagcaaa ttccaagtgg acaacaacaa ccgcctgtta ctgcagcagg     4020

tctcattgcc agagctgcct ggggaataca gcatgaaagt gacaggagaa ggatgtgtct     4080

acctccagac atccttgaaa tacaatattc tcccagaaaa ggaagagttc ccctttgctt     4140

taggagtgca gactctgcct caaacttgtg atgaacccaa agcccacacc agcttccaaa     4200

tctccctaag tgtcagttac acagggagcc gctctgcctc caacatggcg atcgttgatg     4260

tgaagatggt ctctggcttc attcccctga agccaacagt gaaaatgctt gaaagatcta     4320

accatgtgag ccggacagaa gtcagcagca accatgtctt gatttacctt gataaggtgt     4380

caaatcagac actgagcttg ttcttcacgg ttctgcaaga tgtcccagta agagatctga     4440

aaccagccat agtgaaagtc tatgattact acgagacgga tgagtttgca attgctgagt     4500

acaatgctcc ttgcagcaaa gatcttggaa atgcttgaag accacaaggc tgaaaagtgc     4560

tttgctggag tcctgttctc agagctccac agaagacacg tgtttttgta tctttaaaga     4620

cttgatgaat aaacactttt tctggtcaat gtcaaaaaaa aaaaaaaaaa aaaaaaaa       4678


<210>  390
<211>  2931
<212>  DNA
<213>  homo sapiens

<400>  390
aagtaattgt ccgtgtcagg aaggtaggcg tgccaagccg cggctctgcg gagaaaccac       60

gaccaccgcg gccgccggaa acccaaagcg ctccagagcg tccccgggtg gccgggcagc      120

accagggaca gcgcccggga ctccactggg gaccggctcc tgggcttccc agcgtcgcgg      180

gtagaggtac agctgctccg tgtgccgcag gctccagatt ctcgccaccc cacccctccc      240

tcagaaactc ggactgctct cgtctgccgt gtggttctct tttcttccga aaggccagtg      300

tcttatctct ccacttcaag tccagaggac ttgctcagtc tcctcccctt aagtcatttc      360

caccatcctc aggcagctgt gggaagccga gagtcctgga ctgttcgtcc gggtgccagc      420

gctggcagtc ccagtccgtc cggtgcagca gcccggcgca ttcccctctc tccctccctc      480

ttgctctccc tccctttctg tcttcctctc tttcctcctc tactgctccc tccctctctt      540

gcctcttaag tttcctgcac cgtgaatcca actgtgccaa gccttggctc ccgcgaacca      600

atcctgagcg cgacccgggc actgggacgg cgactccgcc aaagctggac gaggcagccg      660

gacccgtctg cgctcgagca tggagacgga gcgcctggga gggcacgtcc ggggcgctgg      720

agacgccagg cccgagtagc ttctccatgg agcctgccca gagcggtccc ttctcgcagg      780

attcgcccca agtcctgtgc ggctgctgag agcgctcctt gctctgtaaa gtggatgtca      840

ggtggatcta tgtttctgaa ggaacaaaga ctcaaagaag gcaccgccaa ggaagtttga      900

gacgcgggag aatgcaggct gcgtgctggt acgtgctttt cctcctgcag cccaccgtct      960

acttggtcac atgtgccaat ttaacgaacg gtggaaagtc agaacttctg aaatcaggaa     1020

gcagcaaatc cacactaaag cacatatgga cagaaagcag caaagacttg tctatcagcc     1080

gactcctgtc acagactttt cgtggcaaag agaatgatac agatttggac ctgagatatg     1140

acaccccaga accttattct gagcaagacc tctgggactg gctgaggaac tccacagacc     1200

ttcaagagcc tcggcccagg gccaagagaa ggcccattgt taaaacgggc aagtttaaga     1260

aaatgtttgg atggggcgat tttcattcca acatcaaaac agtgaagctg aacctgttga     1320

taactgggaa aattgtagat catggcaatg ggacatttag tgtttatttc aggcataatt     1380

caactggtca agggaatgta tctgtcagct tggtaccccc tacaaaaatc gtggaatttg     1440

acttggcaca acaaaccgtg attgatgcca aagattccaa gtcttttaat tgtcgcattg     1500

aatatgaaaa ggttgacaag gctaccaaga acacactctg caactatgac ccttcaaaaa     1560

cctgttacca ggagcaaacc caaagtcatg tatcctggct ctgctccaag ccctttaagg     1620

tgatctgtat ttacatttcc ttttatagta cagattataa actggtacag aaagtgtgcc     1680

ctgactacaa ctaccacagt gacacacctt actttccctc gggatgaagg tgaacatggg     1740

ggtgagactg aagcctgagg aattaaaggt catatgacag ggctgttacc tcaaagaaga     1800

aggtcacatc tgttgcctgg aatgtgtcta cactgctgct cttgtcaact ggctgcaaaa     1860

tacactagtg gaaaacactc tgatgtaatt tctgcccagt cagcttcatc cctcagtata     1920

attgtaaatc atcacagatt ttgaattcac acctgaagac atgctctcac atatagaggt     1980

acacaaacac accgtcatgc acatttcagc ttgcgtctat catgattcct gttgagaggg     2040

ctttcattgt ctgactcata atggttcagg atcaactatc atcaaacgga aggattaact     2100

agacagagaa tgtttctaac agttgctgtt atggaaatct cttttaaagt cttgagtaca     2160

tgctaatcaa taatctccac tcatgcattc ctactgcttg gagtagctgt actggtaaat     2220

actactgtag gagtatctgc ttgttaaaat ggaaaaatgt gtctttagag ctcagtattc     2280

tttattttac aaacacaaca aaatgtagta acttttttcc agcatacagt aggcacattc     2340

aaagtggtcc aagatggctc ttttttcttt gaaaggggcc tgttctcagt aaagatgagc     2400

aaacatttgg aatttacatg tgggcagaca ttgggataac aactttcatc accaatcatt     2460

ggacttttgt gaagttgaca ccagctaagg ctgcttaaaa taagttctga tcattatata     2520

agaagggaaa tgcctggcag acaccatgta agttataagt gtctgtctta tctttactac     2580

acatattgta acaaattcaa tatcctagtc ttcatttgta tgaatggttt gtattgtaca     2640

tagtttaacc aagtgttatt tgagctgctt attaatatta acttgtactt gtctctctgc     2700

ttgttattgg ttaagaaaaa aggatatgag gaattcattt tatcaatgta gctgtgaagg     2760

ccattaaaaa gacaaactta atgtacagag catttattca gatcaagtat tgttgaaagc     2820

tatacatata caacattaca gtctgtctgt atttagatat tttatttctg gaaaaaatga     2880

aatgtacata aaaataaaac acttaaagtt gagtttcaat aaaaaaaaaa a              2931


<210>  391
<211>  5214
<212>  DNA
<213>  homo sapiens

<400>  391
agtctttgtg cagtcagggc ttctgctggg cagggccggc tgttaatctc gcctggcgga       60

gcggacaccg gggcgtggtg ggggagatgg gccttatagg tggcgtccgc tggtgagaaa      120

caccttgcgc aggtaaaagg gtggcggcga gagggagttc ccacccgtgg ctttcttaga      180

gaaatgaagt cttaagtctt aaatagacaa caaggagggg ccgatcggtg tcttttggac      240

gcgtctggag cccctccctc cgccaaagga aaagcccctt ggatgagagg caggcgcttc      300

agagaagcta agaaaagcac ctctccgcgc gccccacctc ctccgcctcg cgctcctcct      360

gagcagcggg cccagactgc gctccggccg cggccctcgc cccgcggagc cctcctaccc      420

cggcccgacg ctcggcccgc gacctgcccc gagccctctc catggaggca gcccgcccct      480

ccggctcctg gaacggagcc ctctgccggc tgctcctgct gaccctcgcg atcttaatat      540

ttgccagtga tgcctgcaaa aatgtgacat tacatgttcc ctccaaacta gatgccgaga      600

aacttgttgg tagagttaac ctgaaagagt gctttacagc tgcaaatcta attcattcaa      660

gtgatcctga cttccaaatt ttggaggatg gttcagtcta tacaacaaat actattctat      720

tgtcctcgga gaagagaagt tttaccatat tactttccaa cactgagaac caagaaaaga      780

agaaaatatt tgtctttttg gagcatcaaa caaaggtcct aaagaaaaga catactaaag      840

aaaaagttct aaggcgcgcc aagagaagat gggctccaat tccttgttcg atgctagaaa      900

actccttggg tccttttcca cttttccttc aacaggttca atctgacacg gcccaaaact      960

ataccatata ctattccata agaggtcctg gagttgacca agaacctcgg aatttatttt     1020

atgtggagag agacactgga aacttgtatt gtactcgtcc tgtagatcgt gagcagtatg     1080

aatcttttga gataattgcc tttgcaacaa ctccagatgg gtatactcca gaacttccac     1140

tgcccctaat aatcaaaata gaggatgaaa atgataacta cccaattttt acagaagaaa     1200

cttatacttt tacaattttt gaaaattgca gagtgggcac tactgtggga caagtgtgtg     1260

ctactgacaa agatgagcct gacacgatgc acacacgcct gaagtactcc atcattgggc     1320

aggtgccacc atcacccacc ctattttcta tgcatccaac tacaggcgtg atcaccacaa     1380

catcatctca gctagacaga gagttaattg acaagtacca gttgaaaata aaagtacaag     1440

acatggatgg tcagtatttt ggtctacaga caacttcaac ttgtatcatt aacattgatg     1500

atgtaaatga ccacttgcca acatttactc gtacttctta tgtgacatca gtggaagaaa     1560

atacagttga tgtggaaatc ttacgagtta ctgttgagga taaggactta gtgaatactg     1620

ctaactggag agctaattat accattttaa agggcaatga aaatggcaat tttaaaattg     1680

taacagatgc caaaaccaat gaaggagttc tttgtgtagt taagcctttg aattatgaag     1740

aaaagcaaca gatgatcttg caaattggtg tagttaatga agctccattt tccagagagg     1800

ctagtccaag atcagccatg agcacagcaa cagttactgt taatgtagaa gatcaggatg     1860

agggccctga gtgtaaccct ccaatacaga ctgttcgcat gaaagaaaat gcagaagtgg     1920

gaacaacaag caatggatat aaagcatatg acccagaaac aagaagtagc agtggcataa     1980

ggtataagaa attaactgat ccaacagggt gggtcaccat tgatgaaaat acaggatcaa     2040

tcaaagtttt cagaagcctg gatagagagg cagagaccat caaaaatggc atatataata     2100

ttacagtcct tgcatcagac caaggaggga gaacatgtac ggggacactg ggcattatac     2160

ttcaagacgt gaatgataac agcccattca tacctaaaaa gacagtgatc atctgcaaac     2220

ccaccatgtc atctgcggag attgttgcgg ttgatcctga tgagcctatc catggcccac     2280

cctttgactt tagtctggag agttctactt cagaagtaca gagaatgtgg agactgaaag     2340

caattaatga tacagcagca cgtctttcct atcagaatga tcctccattt ggctcatatg     2400

tagtacctat aacagtgaga gatagacttg gcatgtctag tgtcacttca ttggatgtta     2460

cactgtgtga ctgcattacc gaaaatgact gcacacatcg tgtagatcca aggattggcg     2520

gtggaggagt acaacttgga aagtgggcca tccttgcaat attgttgggc atagcattgc     2580

tcttttgcat cctgtttacg ctggtctgtg gggcttctgg gacgtctaaa caaccaaaag     2640

taattcctga tgatttagcc cagcagaacc taattgtatc aaacacagaa gctcctggag     2700

atgacaaagt gtattctgcg aatggcttca caacccaaac tgtgggcgct tctgctcagg     2760

gagtttgtgg caccgtggga tcaggaatca aaaacggagg tcaggagacc atcgaaatgg     2820

tgaaaggagg acaccagacc tcggaatcct gccggggggc tggccaccat cacaccctgg     2880

actcctgcag gggaggacac acggaggtgg acaactgcag atacacttac tcggagtggc     2940

acagttttac tcagccccgt cttggtgaaa aagtgtatct gtgtaatcaa gatgaaaatc     3000

acaagcatgc ccaagactat gtcctgacat ataactatga aggaagagga tcggtggctg     3060

ggtctgtagg ttgttgcagt gaacgacaag aagaagatgg gcttgaattt ttggataatt     3120

tggagcccaa atttaggaca ctagcagaag catgcatgaa gagatgagtg tgttctaata     3180

agtctctgaa agccagtggc tttatgactt ttaaaaaaaa ttacaaacca agaatttttt     3240

aaagcagaag atgctatttg tgggggtttt tctctcatta tttggatgga atctctttgg     3300

tcaaatgcac atttacagag agacactata aacaagtaca caaatttttc aatttttaca     3360

tatttttaaa ttacttatct tctatccaag gaggtctaca gagaaattaa agtctgcctt     3420

atttgttaca tttgggtata atgacaacag ccaatttata gtgcaataaa atgtaattaa     3480

ttcaagtcct tattatagac tatttgaagc acaacctaat ggaaaattgt agagaccttg     3540

ctttaacatt atctccagtt aattaagtgt tcatgtggtg cttggaaact gttgttttcc     3600

tgaacatcta aagtgtgtag actgcattct tgctattatt ttattcttgt aatgtgacct     3660

tttcactgtg caaagggaga tttctagcca ggcattgact attacaattt cattttggtg     3720

gagtttagtt ttaggtttta ttgtatataa aatcctgcac tgaatctgtg tctcctctgt     3780

tacctacttt tgccagtgaa atttaagttt taaaatactt tcagaatgta tttttactac     3840

tgcaagtttt tggtctttaa aatgtcaagt agcatctctc tctttctctc tgtctctttc     3900

tgtttctctc tccagttttt tttttttttt taatttccat atgggctaaa gaatccaaat     3960

attttaaaaa tctgtctctc ttttcttctc tcataaagtg aattattcct tttttttgtt     4020

ttatgtaagt gtatatattc ttagtttttc ttgaaatcat tgtaatgtta actttgttgt     4080

ttcaaatatc ttggtgattg cttcattatc tcttcaacaa aaaaaacctt taattttgcc     4140

attgaaactg tagaactatg ccatgctttt attagaagca gtgctctgtg ttaacaacaa     4200

gaatggtgta attagaattg ggatgtggat atttactgta tgacaacaca tttacagttc     4260

tgtaatgcaa ggatgcagtt taaaaatgtg aagtagtgat ggtttttgaa ataagcttta     4320

aaatataggg atcttgaagg ctccctgggg taactatttt ataacttaga taaaatggct     4380

agtcatatct gtgtgtttgt aaagttattt ttttaatatt ttaagattac aattttaaca     4440

aatgtagaaa tgagccaaac tatttaaatt ttaaaacagt aaaacaaaat gaaacttaat     4500

agctcacaaa attccagtcc atgtttcatg acttatttta gtcaatgaat tttctattta     4560

tactaaacat atggacattt taaatgtgtt tctaatattt ttgattatct ataatgtgcc     4620

tgtcttcaat tcacaagatt gggttataac aattatttgc cagattaaca ctagggaatt     4680

atttgataac cagcttatct tatcagtagt tttattgctg atcaggcaaa aatagttttc     4740

caaagttatt tttaataaag tatatacaaa attcttatat attactagtc atgataaagt     4800

aaattaagca gtttttaaaa cttagtgtga gtttgttcat cacaggtctg atatgagttt     4860

aagggatttc gcactccctg aatcagagaa gtaagacccc ttccttagat tcctgttata     4920

cattttttaa aatgtagagt ttgttttgga gacattttca gtgcattgtt attgccatat     4980

ttatataata tgactattct aaaggctgtg aggccatggg gtattggtta agttgcttgc     5040

ttttgctttg tccattttca tcattttaaa atgggggata ataacagaac ttgtttccta     5100

gggccattgt aagtcacttg aataaaaaat agttttgaag catgagagtc atacagagcg     5160

gtccacctaa aaggcactcc tgataataat aaatgatttt aaacaagtaa aaaa           5214


<210>  392
<211>  5260
<212>  DNA
<213>  homo sapiens

<400>  392
agtctttgtg cagtcagggc ttctgctggg cagggccggc tgttaatctc gcctggcgga       60

gcggacaccg gggcgtggtg ggggagatgg gccttatagg tggcgtccgc tggtgagaaa      120

caccttgcgc aggtaaaagg gtggcggcga gagggagttc ccacccgtgg ctttcttaga      180

gaaatgaagt cttaagtctt aaatagacaa caaggagggg ccgatcggtg tcttttggac      240

gcgtctggag cccctccctc cgccaaagga aaagcccctt ggatgagagg caggcgcttc      300

agagaagcta agaaaagcac ctctccgcgc gccccacctc ctccgcctcg cgctcctcct      360

gagcagcggg cccagactgc gctccggccg cggccctcgc cccgcggagc cctcctaccc      420

cggcccgacg ctcggcccgc gacctgcccc gagccctctc catggaggca gcccgcccct      480

ccggctcctg gaacggagcc ctctgccggc tgctcctgct gaccctcgcg atcttaatat      540

ttgccagtga tgcctgcaaa aatgtgacat tacatgttcc ctccaaacta gatgccgaga      600

aacttgttgg tagagttaac ctgaaagagt gctttacagc tgcaaatcta attcattcaa      660

gtgatcctga cttccaaatt ttggaggatg gttcagtcta tacaacaaat actattctat      720

tgtcctcgga gaagagaagt tttaccatat tactttccaa cactgagaac caagaaaaga      780

agaaaatatt tgtctttttg gagcatcaaa caaaggtcct aaagaaaaga catactaaag      840

aaaaagttct aaggcgcgcc aagagaagat gggctccaat tccttgttcg atgctagaaa      900

actccttggg tccttttcca cttttccttc aacaggttca atctgacacg gcccaaaact      960

ataccatata ctattccata agaggtcctg gagttgacca agaacctcgg aatttatttt     1020

atgtggagag agacactgga aacttgtatt gtactcgtcc tgtagatcgt gagcagtatg     1080

aatcttttga gataattgcc tttgcaacaa ctccagatgg gtatactcca gaacttccac     1140

tgcccctaat aatcaaaata gaggatgaaa atgataacta cccaattttt acagaagaaa     1200

cttatacttt tacaattttt gaaaattgca gagtgggcac tactgtggga caagtgtgtg     1260

ctactgacaa agatgagcct gacacgatgc acacacgcct gaagtactcc atcattgggc     1320

aggtgccacc atcacccacc ctattttcta tgcatccaac tacaggcgtg atcaccacaa     1380

catcatctca gctagacaga gagttaattg acaagtacca gttgaaaata aaagtacaag     1440

acatggatgg tcagtatttt ggtctacaga caacttcaac ttgtatcatt aacattgatg     1500

atgtaaatga ccacttgcca acatttactc gtacttctta tgtgacatca gtggaagaaa     1560

atacagttga tgtggaaatc ttacgagtta ctgttgagga taaggactta gtgaatactg     1620

ctaactggag agctaattat accattttaa agggcaatga aaatggcaat tttaaaattg     1680

taacagatgc caaaaccaat gaaggagttc tttgtgtagt taagcctttg aattatgaag     1740

aaaagcaaca gatgatcttg caaattggtg tagttaatga agctccattt tccagagagg     1800

ctagtccaag atcagccatg agcacagcaa cagttactgt taatgtagaa gatcaggatg     1860

agggccctga gtgtaaccct ccaatacaga ctgttcgcat gaaagaaaat gcagaagtgg     1920

gaacaacaag caatggatat aaagcatatg acccagaaac aagaagtagc agtggcataa     1980

ggtataagaa attaactgat ccaacagggt gggtcaccat tgatgaaaat acaggatcaa     2040

tcaaagtttt cagaagcctg gatagagagg cagagaccat caaaaatggc atatataata     2100

ttacagtcct tgcatcagac caaggaggga gaacatgtac ggggacactg ggcattatac     2160

ttcaagacgt gaatgataac agcccattca tacctaaaaa gacagtgatc atctgcaaac     2220

ccaccatgtc atctgcggag attgttgcgg ttgatcctga tgagcctatc catggcccac     2280

cctttgactt tagtctggag agttctactt cagaagtaca gagaatgtgg agactgaaag     2340

caattaatga tacagcagca cgtctttcct atcagaatga tcctccattt ggctcatatg     2400

tagtacctat aacagtgaga gatagacttg gcatgtctag tgtcacttca ttggatgtta     2460

cactgtgtga ctgcattacc gaaaatgact gcacacatcg tgtagatcca aggattggcg     2520

gtggaggagt acaacttgga aagtgggcca tccttgcaat attgttgggc atagcattgc     2580

tcttttgcat cctgtttacg ctggtctgtg gggcttctgg gacgtctaaa caaccaaaag     2640

taattcctga tgatttagcc cagcagaacc taattgtatc aaacacagaa gctcctggag     2700

atgacaaagt gtattctgcg aatggcttca caacccaaac tgtgggcgct tctgctcagg     2760

gagtttgtgg caccgtggga tcaggaatca aaaacggagg tcaggagacc atcgaaatgg     2820

tgaaaggagg acaccagacc tcggaatcct gccggggggc tggccaccat cacaccctgg     2880

actcctgcag gggaggacac acggaggtgg acaactgcag atacacttac tcggagtggc     2940

acagttttac tcagccccgt cttggtgaag aatccattag aggacacact ctgattaaaa     3000

attaaacaat gaaagaaagt gtatctgtgt aatcaagatg aaaatcacaa gcatgcccaa     3060

gactatgtcc tgacatataa ctatgaagga agaggatcgg tggctgggtc tgtaggttgt     3120

tgcagtgaac gacaagaaga agatgggctt gaatttttgg ataatttgga gcccaaattt     3180

aggacactag cagaagcatg catgaagaga tgagtgtgtt ctaataagtc tctgaaagcc     3240

agtggcttta tgacttttaa aaaaaattac aaaccaagaa ttttttaaag cagaagatgc     3300

tatttgtggg ggtttttctc tcattatttg gatggaatct ctttggtcaa atgcacattt     3360

acagagagac actataaaca agtacacaaa tttttcaatt tttacatatt tttaaattac     3420

ttatcttcta tccaaggagg tctacagaga aattaaagtc tgccttattt gttacatttg     3480

ggtataatga caacagccaa tttatagtgc aataaaatgt aattaattca agtccttatt     3540

atagactatt tgaagcacaa cctaatggaa aattgtagag accttgcttt aacattatct     3600

ccagttaatt aagtgttcat gtggtgcttg gaaactgttg ttttcctgaa catctaaagt     3660

gtgtagactg cattcttgct attattttat tcttgtaatg tgaccttttc actgtgcaaa     3720

gggagatttc tagccaggca ttgactatta caatttcatt ttggtggagt ttagttttag     3780

gttttattgt atataaaatc ctgcactgaa tctgtgtctc ctctgttacc tacttttgcc     3840

agtgaaattt aagttttaaa atactttcag aatgtatttt tactactgca agtttttggt     3900

ctttaaaatg tcaagtagca tctctctctt tctctctgtc tctttctgtt tctctctcca     3960

gttttttttt tttttttaat ttccatatgg gctaaagaat ccaaatattt taaaaatctg     4020

tctctctttt cttctctcat aaagtgaatt attccttttt tttgttttat gtaagtgtat     4080

atattcttag tttttcttga aatcattgta atgttaactt tgttgtttca aatatcttgg     4140

tgattgcttc attatctctt caacaaaaaa aacctttaat tttgccattg aaactgtaga     4200

actatgccat gcttttatta gaagcagtgc tctgtgttaa caacaagaat ggtgtaatta     4260

gaattgggat gtggatattt actgtatgac aacacattta cagttctgta atgcaaggat     4320

gcagtttaaa aatgtgaagt agtgatggtt tttgaaataa gctttaaaat atagggatct     4380

tgaaggctcc ctggggtaac tattttataa cttagataaa atggctagtc atatctgtgt     4440

gtttgtaaag ttattttttt aatattttaa gattacaatt ttaacaaatg tagaaatgag     4500

ccaaactatt taaattttaa aacagtaaaa caaaatgaaa cttaatagct cacaaaattc     4560

cagtccatgt ttcatgactt attttagtca atgaattttc tatttatact aaacatatgg     4620

acattttaaa tgtgtttcta atatttttga ttatctataa tgtgcctgtc ttcaattcac     4680

aagattgggt tataacaatt atttgccaga ttaacactag ggaattattt gataaccagc     4740

ttatcttatc agtagtttta ttgctgatca ggcaaaaata gttttccaaa gttattttta     4800

ataaagtata tacaaaattc ttatatatta ctagtcatga taaagtaaat taagcagttt     4860

ttaaaactta gtgtgagttt gttcatcaca ggtctgatat gagtttaagg gatttcgcac     4920

tccctgaatc agagaagtaa gaccccttcc ttagattcct gttatacatt ttttaaaatg     4980

tagagtttgt tttggagaca ttttcagtgc attgttattg ccatatttat ataatatgac     5040

tattctaaag gctgtgaggc catggggtat tggttaagtt gcttgctttt gctttgtcca     5100

ttttcatcat tttaaaatgg gggataataa cagaacttgt ttcctagggc cattgtaagt     5160

cacttgaata aaaaatagtt ttgaagcatg agagtcatac agagcggtcc acctaaaagg     5220

cactcctgat aataataaat gattttaaac aagtaaaaaa                           5260


<210>  393
<211>  4611
<212>  DNA
<213>  homo sapiens

<400>  393
gttacgcatg cgccctggtc accccgcggt ttgtccgcgc ctctgctacc ccctgcgcag       60

gcgctcaagg agctcttgga ctccaggttc ccgcggctgg gagaaaagga ggcggggatc      120

cgaaggggga aatgactctg aggcgcccgg acgtcgctcg gaagccaatc agagagcgtg      180

acgtcagttt ggcgcggagt ttggcggccg gggcttacag tggcgggagt tggaggcgat      240

aacgatttgt gttgtgagag gcgcaagctg cgatttctgc tgaacttgga ggcatttcta      300

cgacttttct ctcagctgag gcttttcctc cgaccctgat gctcttcaat tcggtgctcc      360

gccagcccca gcttggcgtc ctgagaaatg gatggtcttc acaataccct cttcaatccc      420

ttctgactgg ttatcagtgc agtggtaatg atgaacacac ttcttatgga gaaacaggag      480

tcccagttcc tccttttgga tgtaccttct cttctgctcc caatatggaa catgtactag      540

cagttgccaa tgaagaaggc tttgttcgat tgtataacac agaatcacaa agtttcagaa      600

agaagtgctt caaagaatgg atggctcact ggaatgccgt ctttgacctg gcctgggttc      660

ctggtgaact taaacttgtt acagcagcag gtgatcaaac agccaaattt tgggacgtaa      720

aagctggtga gctgattgga acatgcaaag gtcatcaatg cagcctcaag tcagttgcct      780

tttctaagtt tgagaaagct gtattctgta cgggtggaag agatggcaac attatggtct      840

gggataccag gtgcaacaaa aaagatgggt tttataggca agtgaatcaa atcagtggag      900

ctcacaatac ctcagacaag caaacccctt caaaacccaa gaagaaacag aattcaaaag      960

gacttgctcc ttctgtggat ttccagcaaa gtgttactgt ggtcctcttt caagacgaga     1020

ataccttagt ctcagcagga gctgtggatg ggataatcaa agtatgggat ttacgtaaga     1080

attatactgc ttatcgacaa gaacccatag catccaagtc tttcctgtac ccaggtagca     1140

gcactcgaaa acttggatat tcaagtctga ttttggattc cactggctct actttatttg     1200

ctaattgcac agacgataac atctacatgt ttaatatgac tgggttgaag acttctccag     1260

tggctatttt caatggacac cagaactcta ccttttatgt aaaatccagc cttagtccag     1320

atgaccagtt tttagtcagt ggctcaagtg atgaagctgc ctacatatgg aaggtctcca     1380

caccctggca acctcctact gtgctcctgg gtcattctca agaggtcacg tctgtgtgct     1440

ggtgtccatc tgacttcaca aagattgcta cctgttctga tgacaataca ctaaaaatct     1500

ggcgcttgaa tagaggctta gaggagaaac caggaggtga taaactttcc acggtgggtt     1560

gggcctctca gaagaaaaaa gagtcaagac ctggcctagt aacagtaacg agtagccaga     1620

gtactcctgc caaagccccc agggtaaagt gcaatccatc caattcttcc ccgtcatccg     1680

cagcttgtgc cccaagctgt gctggagacc tccctcttcc ttcaaatact cctacgttct     1740

ctattaaaac ctctcctgcc aaggcccggt ctcccatcaa cagaagaggc tctgtctcct     1800

ccgtctctcc caagccacct tcatctttca agatgtcgat tagaaactgg gtgacccgaa     1860

caccttcctc atcaccaccc atcactccac ctgcttcgga gaccaagatc atgtctccga     1920

gaaaagccct tattcctgtg agccagaagt catcccaagc agaggcttgc tctgagtcta     1980

gaaatagagt aaagaggagg ctagactcaa gctgtctgga gagtgtgaaa caaaagtgtg     2040

tgaagagttg taactgtgtg actgagcttg atggccaagt tgaaaatctt catttggatc     2100

tgtgctgcct tgctggtaac caggaagacc ttagtaagga ctctctaggt cctaccaaat     2160

caagcaaaat tgaaggagct ggtaccagta tctcagagcc tccgtctcct atcagtccgt     2220

atgcttcaga aagctgtgga acgctacctc ttcctttgag accttgtgga gaagggtctg     2280

aaatggtagg caaagagaat agttccccag agaataaaaa ctggttgttg gccatggcag     2340

ccaaacggaa ggctgagaat ccatctccac gaagtccgtc atcccagaca cccaattcca     2400

ggagacagag cggaaagaca ttgccaagcc cggtcaccat cacgcccagc tccatgagga     2460

aaatctgcac atacttccat agaaagtccc aggaggactt ctgtggtcct gaacactcaa     2520

cagaattata gattctaatc tgagtgagtt actgagcttt ggtccactaa aacaagctga     2580

gctttggtcc actaaaacaa gatgaaaaat acaagagtga ctctataact ctggtcttta     2640

agaaagctgc cttttcattt ttagacaaaa tcttttcaac gctgaaatgt acctaatctg     2700

gttctactac cataatgtat atgcagcttc ccgaggatga atgctgtgtt taaatttcat     2760

aaagtaaatt tgtcactcta gcattttgaa tgaatagtct tcacttttta aattattcat     2820

cttctctata ataatgacat cccagttcat ggaggcaaaa aacaagtttc ttgttatcct     2880

gaaactttct atgctcagtg gaaagtatct gccagccaca gcatgaggcc tgtgaaggct     2940

gactgagaaa tcctctgctg aagacccctg gttctgttct gcctccaaca tgtataattt     3000

tatttgaaat acataatctt ttcactatgc ttttgtgggg ttttttttaa gtatgtgtaa     3060

aaatgtgatg ctcagataag tacatttata tcagttcagt gttaaaatgc agtctcttga     3120

gttaaagtca tctttatttt aaatgcagtg ataaatgtca actcttcgga gaaactagga     3180

gaacaacaac agaaagctgt gtttgtcttt tttctctcaa atatatctcc cgtatgagat     3240

ttcaggtccc catgttttca ccaagcaatc tgctatgtca gccaacccaa catcactttc     3300

tacaggaggt tatgattttt gccatttact agaggaagat gttttatgaa atcaatttgg     3360

ggtttgaatt caggtgcagt catcagttct ttaggggctg caatgtttta aaaaaaataa     3420

gtcatcagat tttaagaaaa aagtgatgat ttcttattga tatttttgta acagaatata     3480

gctcttaact gaaaatccag aaccagaaac ataaatcttg agtttctttt catgtacata     3540

aaaagcaata gccttttagt atagatagcc ctgagccaaa aagtaataga attttctcta     3600

gatatttaat acagagagtg tatagactga ctctaagtta ataatgtgca aaatatctta     3660

aacatccctc cccttattca acaattatgt atcagtgatc ttgaaccatt gttttatatt     3720

tttcaccttt gtaacctcat ggaaagaggc tttacatact ttctatgtac tatttactta     3780

gaagggagcc cccttccagt catgaaactt catttgtttt atccatatcc ctgaggactg     3840

tgtagacttt atgtcagttt ttgtcattat ttgaaaatct attctgacaa ctttttaatt     3900

cctttgatct tataagttaa agctgtaaca actgaaattg catggatcaa gtaagcatag     3960

ttttatccag ggagaaaaat aaaaggaagc catagaattg ctctggtcaa aaccaagcac     4020

accatagcct taactgaata tttaggaaat ctgcctaatc tgcttatatt tggtgtttgt     4080

tttttgactg ttgggctttg ggaagatgtt atttatgacc aatatctgcc agtaacgctg     4140

tttatctcac ttgctttgaa agccaatggg ggaaaaaaat ccatgaaaaa aaaaagattg     4200

ataaagtaga tgattttgtt tgtatcccta cccatctcct ggcagcccta ctgagtgaaa     4260

ttgggataca tttggctgtc agaaattata ccgagtctac tgggtataac atgtctcact     4320

tggaaagcta gtacttttaa atgggtgcca aaggtcaact gtaatgagat aattatccct     4380

gcctgtgtcc atgtcagact ttgagctgat cctgaataat aaagcctttt accttatctg     4440

atgtcctttt ctgagctttt tgcattacct agaagcagtc tacaaaaaag aactatagta     4500

gtcaagaatc ccttctactt gttcattaaa atgtttattc ccaaagttat aatctatttc     4560

aagctgaaag agcttttaat aaaaaacatc ttgcttgaaa aaaaaaaaaa a              4611


<210>  394
<211>  5836
<212>  DNA
<213>  homo sapiens

<400>  394
gctttgccca gtagttggaa agtgaactcg actcgtgatg gttctcctgt cactttggtt       60

gatagcagcc gctctggtag aggttaggac ttcagctgat ggacaagctg gtaatgaaga      120

aatggtgcaa atagatttac caataaagag atatagagag tatgagctgg tgactccagt      180

cagcacaaat ctagaaggac gctatctctc ccatactctt tctgcgagtc acaaaaagag      240

gtcagcgagg gacgtgtctt ccaaccctga gcagttgttc tttaacatca cggcatttgg      300

aaaagatttt catctgcgac taaagcccaa cactcaacta gtagctcctg gggctgttgt      360

ggagtggcat gagacatctc tggtgcctgg gaatataacc gatcccatta acaaccatca      420

accaggaagt gctacgtata gaatccggag aacagagcct ttgcagacta actgtgctta      480

tgttggtgac atcgtggaca ttccaggaac ctctgttgcc atcagcaact gtgatggtct      540

ggctggaatg ataaaaagtg ataatgaaga gtatttcatt gaacccttgg aaagaggtaa      600

acagatggag gaagaaaaag gaaggattca tgttgtctac aagagatcag ctgtagaaca      660

ggctcccata gacatgtcca aagacttcca ctacagagag tcggacctgg aaggccttga      720

tgatctaggt actgtttatg gcaacatcca ccagcagctg aatgaaacaa tgagacgccg      780

cagacacgcg ggagaaaacg attacaatat cgaggtactg ctgggagtgg atgactctgt      840

ggtccgtttc catggcaaag agcacgtcca aaactacctc ctgaccctaa tgaacattgt      900

gaatgaaatt taccatgatg agtccctcgg agtgcatata aatgtggtcc tggtgcgcat      960

gataatgctg ggatatgcaa agtccatcag cctcatagaa aggggaaacc catccagaag     1020

cttggagaat gtgtgtcgct gggcgtccca acagcaaaga tctgatctca accactctga     1080

acaccatgac catgcaattt ttttaaccag gcaagacttt ggacctgctg gaatgcaagg     1140

atatgctcca gtcaccggca tgtgtcatcc agtgagaagt tgtaccctga atcatgagga     1200

tggtttttca tctgcttttg tagtagccca tgaaacgggc catgtgttgg gaatggagca     1260

tgatggacaa ggcaacaggt gtggtgatga gactgctatg ggaagtgtca tggctccctt     1320

ggtacaagca gcattccatc gttaccactg gtcccgatgc agtggtcaag aactgaaaag     1380

atatatccat tcctatgact gtctccttga tgaccctttt gatcatgatt ggcctaaact     1440

cccagaactt cctggaatca attattctat ggatgagcaa tgtcgttttg attttggtgt     1500

tggctataaa atgtgcaccg cgttccgaac ctttgaccca tgtaaacagc tgtggtgtag     1560

ccatcctgat aatccctact tttgtaagac taaaaaggga cctccacttg atgggactga     1620

atgtgctgct ggaaaatggt gctataaggg tcattgcatg tggaagaatg ctaatcagca     1680

aaaacaagat ggcaattggg ggtcatggac taaatttggc tcctgttctc ggacatgtgg     1740

aactggtgtt cgtttcagaa cacgccagtg caataatccc atgcccatca atggtggtca     1800

ggattgtcct ggtgttaatt ttgagtacca gctttgtaac acagaagaat gccaaaaaca     1860

ctttgaggac ttcagagcac agcagtgtca gcagcgaaac tcccactttg aataccagaa     1920

taccaaacac cactggttgc catatgaaca tcctgacccc aagaaaagat gccaccttta     1980

ctgtcagtcc aaggagactg gagatgttgc ttacatgaaa caactggtgc atgatggaac     2040

gcactgttct tacaaagatc catatagcat atgtgtgcga ggagagtgtg tgaaagtggg     2100

ctgtgataaa gaaattggtt ctaataaggt tgaggataag tgtggtgtct gtggaggaga     2160

taattcccac tgccgaaccg tgaaggggac atttaccaga actcccagga agcttgggta     2220

ccttaagatg tttgatatac cccctggggc tagacatgtg ttaatccaag aagacgaggc     2280

ttctcctcat attcttgcta ttaagaacca ggctacaggc cattatattt taaatggcaa     2340

aggggaggaa gccaagtcgc ggaccttcat agatcttggt gtggagtggg attataacat     2400

tgaagatgac attgaaagtc ttcacaccga tggaccttta catgatcctg ttattgtttt     2460

gattatacct caagaaaatg atacccgctc tagcctgaca tataagtaca tcatccatga     2520

agactctgta cctacaatca acagcaacaa tgtcatccag gaagaattag atacttttga     2580

gtgggctttg aagagctggt ctcagtgttc caaaccctgt ggtggaggtt tccagtacac     2640

taaatatgga tgccgtagga aaagtgataa taaaatggtc catcgcagct tctgtgaggc     2700

caacaaaaag ccgaaaccta ttagacgaat gtgcaatatt caagagtgta cacatccact     2760

ctgggtagca gaagaatggg aacactgcac caaaacctgt ggaagttctg gctatcagct     2820

tcgcactgta cgctgccttc agccactcct tgatggcacc aaccgctctg tgcacagcaa     2880

atactgcatg ggtgaccgtc ccgagagccg ccggccctgt aacagagtgc cctgccctgc     2940

acagtggaaa acaggaccct ggagtgagtg ttcagtgacc tgcggtgaag gaacggaggt     3000

gaggcaggtc ctctgcaggg ctggggacca ctgtgatggt gaaaagcctg agtcggtcag     3060

agcctgtcaa ctgcctcctt gtaatgatga accatgtttg ggagacaagt ccatattctg     3120

tcaaatggaa gtgttggcac gatactgctc cataccaggt tataacaagt tatgttgtga     3180

gtcctgcagc aagcgcagta gcaccctgcc accaccatac cttctagaag ctgctgaaac     3240

tcatgatgat gtcatctcta accctagtga cctccctaga tctctagtga tgcctacatc     3300

tttggttcct tatcattcag agacccctgc aaagaagatg tctttgagta gcatctcttc     3360

agtgggaggt ccaaatgcat atgctgcttt caggccaaac agtaaacctg atggtgctaa     3420

tttacgccag aggagtgctc agcaagcagg aagtaagact gtgagactgg tcaccgtacc     3480

atcctcccca cccaccaaga gggtccacct cagttcagct tcacaaatgg ctgctgcttc     3540

cttctttgca gccagtgatt caataggtgc ttcttctcag gcaagaacct caaagaaaga     3600

tggaaagatc attgacaaca gacgtccgac aagatcatcc accttagaaa gatgagaaag     3660

tgaaccaaaa aggctagaaa ccagaggaaa acctggacaa cctctctctt cccatggtgc     3720

atatgcttgt ttaaagtgga aatctctata gatcgtcagc tcattttatc tgtaattgga     3780

agaacagaaa gtgctggctc actttctagt tgctttcatc ctccttttgt tctgcattga     3840

ctcatttacc agaattcatt ggaagaaatc accaaagatt attacaaaag aaaaatatgt     3900

tgctaagatt gtgttggtcg ctctctgaag cagaaaaggg actggaacca attgtgcata     3960

tcagctgact ttttgtttgt tttagaaaag ttacagtaaa aattaaaaag agataccaat     4020

ggtttacact ttaacaagaa attttggata tggaacaaag aattcttaga cttgtattcc     4080

tatttatcta tattagaaat attgtatgag caaatttgca gctgttgtgt aaatactgta     4140

tattgcaaaa atcagtatta ttttaagaga tgtgttctca aatgattgtt tactatatta     4200

catttctgga tgttctaggt gcctgtcgtt gagtattgcc ttgtttgaca ttctataggt     4260

taattttcaa agcagagtat tacaaaagag aagttagaat tacagctact gacaatataa     4320

agggttttgt tgaatcaaca atgtgatacg taaattatag aaaaagaaaa gaaacacaaa     4380

agctatagat atacagatat cagcttacct attgccttct atacttataa tttaaaggat     4440

tggtgtctta gtacacttgt ggtcacaggg atcaacgaat agtaaataat gaactcgtgc     4500

aagacaaaac tgaaaccctc tttccaggac ctcagtaggc accgttgagg tgtcctttgt     4560

ttttgtgtgt gtgtgttctt ttttaatttt cgcattgttg acagatacaa acagttatac     4620

tcaatgtact gtaataatcg caaaggaaaa agttttggga taacttattt gtatgttggt     4680

agctgagaaa aatatcatca gtctagaatt gatatttgag tatagtagag ctttggggct     4740

ttgaaggcag gttcaagaaa gcatatgtcg atggttgaga tatttatttt ccatatggtt     4800

catgttcaaa tgttcacaac cacaatgcat ctgactgcaa taatgtgcta ataatttatg     4860

tcagtagtca ccttgctcac agcaaagcca gaaatgctct ctccagggag tagatgtaaa     4920

gtacttgtac atagaattca gaactgaaga tatttattaa aagttgattt tttttcttga     4980

tagtattttt atgtactaaa tatttacact aatatcaatt acatattttg gtaaactaga     5040

gagacataat tagagatgca tgctttgttc tgtgcataga gacctttaag caaactacta     5100

cagccaactc aaaagctaaa actgaacaaa tttgatgtta tgcaaacatc ttgcattttt     5160

agtagttgat attaagttga tgacttgttt cccttcaagg aaacattaaa ttgtatggac     5220

tcagctagct gttcaatgaa attgtgaatt agaaacattt ttaaaagttt ttgaaagaga     5280

taagtgcatc atgaattaca tgtacatgag aggagatagt gatatcagca taatgatttt     5340

gaggtcagta cctgagctgt ctaaaaatat attatacaaa ctaaaatgta gatgaattaa     5400

cctctcaaag cacagaatgt gcaagaactt ttgcatttta atcgttgtaa actaacagct     5460

taaactattg actctatacc tctaaagaat tgctgctact ttgtgcaaga actttgaagg     5520

tcaaattagg caaattccag atagtaaaac aatccctaag ccttaagtct tttttttttc     5580

ctaaaaattc ccatagaata aaattctctc tagtttactt gtgtgtgcat acatctcatc     5640

cacaggggaa gataaagatg gtcacacaaa cagtttccat aaagatgtac atattcatta     5700

tacttctgac ctttgggctt tcttttctac taagctaaaa attccttttt atcaaagtgt     5760

acactactga tgctgtttgt tgtactgaga gcacgtacca ataaaaatgt taacaaaata     5820

taaaaaaaaa aaaaaa                                                     5836


<210>  395
<211>  3976
<212>  DNA
<213>  homo sapiens

<400>  395
ctgggtcctg tgtgtgccac aggggtgggg tgtccagcga gcggtctcct cctcctgcta       60

gtgctgctgc ggcgtcccgc ggcctccccg agtcgggcgg gaggggagag cgggtgtgga      120

tttgtcttga cggtaattgt tgcgtttcca cgtctcggag gcctgcgcgc tgggttgctc      180

cttcttcggg agcgagctgt tctcagcgat cccactccca gccggggctc cccacacaca      240

ctgggctgcg tgcgtgtgga gtgggacccg cgcacacgcg tgtctctgga cagctacggc      300

gccgaaagaa ctaaaattcc agatggcaaa ctcaatgaat ggcagaaacc ctggtggtcg      360

aggaggaaat ccccgaaaag gtcgaatttt gggtattatt gatgctattc aggatgcagt      420

tggaccccct aagcaagctg ccgcagatcg caggaccgtg gagaagactt ggaagctcat      480

ggacaaagtg gtaagactgt gccaaaatcc caaacttcag ttgaaaaata gcccaccata      540

tatacttgat attttgcctg atacatatca gcatttacga cttatattga gtaaatatga      600

tgacaaccag aaacttgccc aactcagtga gaatgagtac tttaaaatct acattgatag      660

ccttatgaaa aagtcaaaac gggcaataag actctttaaa gaaggcaagg agagaatgta      720

tgaagaacag tcacaggaca gacgaaatct cacaaaactg tcccttatct tcagtcacat      780

gctggcagaa atcaaagcaa tctttcccaa tggtcaattc cagggagata actttcgtat      840

cacaaaagca gatgctgctg aattctggag aaagtttttt ggagacaaaa ctatcgtacc      900

atggaaagta ttcagacagt gccttcatga ggtccaccag attagctctg gcctggaagc      960

aatggctcta aaatcaacaa ttgatttaac ttgcaatgat tacatttcag tttttgaatt     1020

tgatattttt accaggctgt ttcagccttg gggctctatt ttgcggaatt ggaatttctt     1080

agctgtgaca catccaggtt acatggcatt tctcacatat gatgaagtta aagcacgact     1140

acagaaatat agcaccaaac ccggaagcta tattttccgg ttaagttgca ctcgattggg     1200

acagtgggcc attggctatg tgactgggga tgggaatatc ttacagacca tacctcataa     1260

caagccctta tttcaagccc tgattgatgg cagcagggaa ggattttatc tttatcctga     1320

tgggaggagt tataatcctg atttaactgg attatgtgaa cctacacctc atgaccatat     1380

aaaagttaca caggaacaat atgaattata ttgtgaaatg ggctccactt ttcagctctg     1440

taagatttgt gcagagaatg acaaagatgt caagattgag ccttgtgggc atttgatgtg     1500

cacctcttgc cttacggcat ggcaggagtc ggatggtcag ggctgccctt tctgtcgttg     1560

tgaaataaaa ggaactgagc ccataatcgt ggaccccttt gatccaagag atgaaggctc     1620

caggtgttgc agcatcattg acccctttgg catgccgatg ctagacttgg acgacgatga     1680

tgatcgtgag gagtccttga tgatgaatcg gttggcaaac gtccgaaagt gcactgacag     1740

gcagaactca ccagtcacat caccaggatc ctctcccctt gcccagagaa gaaagccaca     1800

gcctgaccca ctccagatcc cacatctaag cctgccaccc gtgcctcctc gcctggatct     1860

aattcagaaa ggcatagtta gatctccctg tggcagccca acgggttcac caaagtcttc     1920

tccttgcatg gtgagaaaac aagataaacc actcccagca ccacctcctc ccttaagaga     1980

tcctcctcca ccgccacctg aaagacctcc accaatccca ccagacaata gactgagtag     2040

acacatccat catgtggaaa gcgtgccttc cagagacccg ccaatgcctc ttgaagcatg     2100

gtgccctcgg gatgtgtttg ggactaatca gcttgtggga tgtcgactcc taggggaggg     2160

ctctccaaaa cctggaatca cagcgagttc aaatgtcaat ggaaggcaca gtagagtggg     2220

ctctgaccca gtgcttatgc ggaaacacag acgccatgat ttgcctttag aaggagctaa     2280

ggtcttttcc aatggtcacc ttggaagtga agaatatgat gttcctcccc ggctttctcc     2340

tcctcctcca gttaccaccc tcctccctag cataaagtgt actggtccgt tagcaaattc     2400

tctttcagag aaaacaagag acccagtaga ggaagatgat gatgaataca agattccttc     2460

atcccaccct gtttccctga attcacaacc atctcattgt cataatgtaa aacctcctgt     2520

tcggtcttgt gataatggtc actgtatgct gaatggaaca catggtccat cttcagagaa     2580

gaaatcaaac atccctgact taagcatata tttaaaggga gatgtttttg attcagcctc     2640

tgatcccgtg ccattaccac ctgccaggcc tccaactcgg gacaatccaa agcatggttc     2700

ttcactcaac aggacgccct ctgattatga tcttctcatc cctccattag gtgaagatgc     2760

ttttgatgcc ctccctccat ctctcccacc tcccccacct cctgcaaggc atagtctcat     2820

tgaacattca aaacctcctg gctccagtag ccggccatcc tcaggacagg atctttttct     2880

tcttccttca gatccctttg ttgatctagc aagtggccaa gttcctttgc ctcctgctag     2940

aaggttacca ggtgaaaatg tcaaaactaa cagaacatca caggactatg atcagcttcc     3000

ttcatgttca gatggttcac aggcaccagc cagaccccct aaaccacgac cgcgcaggac     3060

tgcaccagaa attcaccaca gaaaacccca tgggcctgag gcggcattgg aaaatgtcga     3120

tgcaaaaatt gcaaaactca tgggagaggg ttatgccttt gaagaggtga agagagcctt     3180

agagatagcc cagaataatg tcgaagttgc ccggagcatc ctccgagaat ttgccttccc     3240

tcctccagta tccccacgtc taaatctata gcagccagaa ctgtagacac caaaatggaa     3300

agcaatcgat gtattccaag agtgtggaaa taaagagaac tgagatggaa ttcaagagag     3360

aagtgtctcc tcctcgtgta gcagcttgag aagaggcttg ggagtgcagc ttctcaaagg     3420

agaccgatgc ttgctcagga tgtcgacagc tgtggcttcc ttgtttttgc tagccatatt     3480

tttaaatcag ggttgaactg acaaaaataa tttaaagacg tttacttccc ttgaactttg     3540

aacctgtgaa atgctttacc ttgtttacag tttggcaaag ttgcagtttg ttcttgtttt     3600

tagtttagtt ttgttttggt gttttgatac ctgtactgtg ttcttcacag accctttgta     3660

gcgtggtcag gtctgctgta acatttccca ccaactctct tgctgtccac atcaacagct     3720

aaatcattta ttcatatgga tctctaccat ccccatgcct tgcccaggtc cagttccatt     3780

tctctcattc acaagatgct ttgaaggttc tgattttcaa ctgatcaaac taatgcaaaa     3840

aaaaaaaagt atgtattctt cactactgag tttcttcttt ggaaaccatc actattgaga     3900

gatgggaaaa acctgaatgt ataaagcatt tatttgtcaa taaactgcct tttgtaaggg     3960

gttttcacat aacata                                                     3976


<210>  396
<211>  5762
<212>  DNA
<213>  homo sapiens

<400>  396
attgggtaca tgcgcagtgc cgctcgcgcg ggccgcgcca atcctgcagc gccttcaaca       60

ggtttcgggc ggcgaattcc agttctccgg gttttggggc tccctgcggg aggcagtgct      120

ggatctggga atctctagga aaggaaagag caaaggaggg gaaagatggg gggctgcagg      180

aaatttggtg agcggcctcc acctaaacga cttactaggg aagctatgcg aaattattta      240

aaagagcgag gggatcaaac agtacttatt cttcatgcaa aagttgcaca gaagtcatat      300

ggaaatgaaa aaaggttttt ttgcccacct ccttgtgtat atcttatggg cagtggatgg      360

aagaaaaaaa aagaacaaat ggaacgcgat ggttgttctg aacaagagtc tcaaccgtgt      420

gcatttattg ggataggaaa tagtgaccaa gaaatgcagc agctaaactt ggaaggaaag      480

aactattgca cagccaaaac attgtatata tctgactcag acaagcgaaa gcacttcatg      540

ttgtctgtaa agatgttcta tggcaacagt gatgacattg gtgtgttcct cagcaagcgg      600

ataaaagtca tctccaaacc ttccaaaaag aagcagtcat tgaaaaatgc tgacttatgc      660

attgcctcag gaacaaaggt ggctctgttt aatcgactac gatcccagac agttagtacc      720

agatacttgc atgtagaagg aggtaatttt catgccagtt cacagcagtg gggagccttt      780

tttattcatc tcttggatga tgatgaatca gaaggagaag aattcacagt ccgagatggc      840

tacatccatt atggacaaac agtcaaactt gtgtgctcag ttactggcat ggcactccca      900

agattgataa ttaggaaagt tgataagcag accgcattat tggatgcaga tgatcctgtg      960

tcacaactcc ataaatgtgc attttacctt aaggatacag aaagaatgta tttgtgcctt     1020

tctcaagaaa gaataattca atttcaggcc actccatgtc caaaagaacc aaataaagag     1080

atgataaatg atggcgcttc ctggacaatc attagcacag ataaggcaga gtatacattt     1140

tatgagggaa tgggccctgt ccttgcccca gtcactcctg tgcctgtggt agagagcctt     1200

cagttgaatg gcggtgggga cgtagcaatg cttgaactta caggacagaa tttcactcca     1260

aatttacgag tgtggtttgg ggatgtagaa gctgaaacta tgtacaggtg tggagagagt     1320

atgctctgtg tcgtcccaga catttctgca ttccgagaag gttggagatg ggtccggcaa     1380

ccagtccagg ttccagtaac tttggtccga aatgatggaa tcatttattc caccagcctt     1440

acctttacct acacaccaga accagggccg cggccacatt gcagtgcagc aggagcaatc     1500

cttcgagcca attcaagcca ggtgccccct aacgaatcaa acacaaacag cgagggaagt     1560

tacacaaacg ccagcacaaa ttcaaccagt gtcacatcat ctacagccac agtggtatcc     1620

taactaccgt ctttttgcta ggacttaaac tgacttgagt gtggcaaaaa gttaacaaaa     1680

aaggagaaaa aatgaacaat cgtttgtggt ttcttgggaa aacttttcat accaggtgat     1740

actattcaaa aaccccgttg tctccctgca agtgctgatt tgaaatgcag aagccacagt     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa aaaaaaatca aaatgtataa atattggaaa     1860

tcaagttttt cagctgtttt gttggttggt tggttggttt ttgtttggtt ttgtttaaat     1920

gggcaagaag taaataatgt ggctggaata caagttgaac aaactagaag acacaaatct     1980

aacatagttt ttatggacca aggaacttgt atattgtata agctttagta aaaggtacat     2040

tttcaccata ccttttttta tatcacggta ttatagtaca ccttgttacc aaataggttg     2100

ttctcttccc cacccacctt tgagcttttg ctctaaaata cattcaggtt ccaagcctga     2160

ccatccttgt ttaatctatc atactcttcc aggttttttt tttttggtct aaggctggaa     2220

cttttttctt ttttttcagc tgaagtctta tgacttttca tgagtcaaaa ttgtttggat     2280

ttcagcaagt caaatcttgc aaaggcctgc atattttttt taagattata tgaagtctgt     2340

gcaaaagctt taaaaaaatg cctctgcctt gcctgcaata catgcaatgt atgttaactt     2400

agtctctctt ctcagacact gttggtagtt atttctgtgt tttccttttt ttaaaaaaaa     2460

atatggactt attgtggtta tctgagaggt tctaacattc acatgcaatt tggtgtggcc     2520

atttagctat taatgagtta atggcgcaga acttgttgat atttgaagtg ttctctcccc     2580

ttttcccatg acgtaaatac ataggtgtgt tccaggattt gttcaggttt ttcccccctc     2640

ctaatcttgt acataacttg tattatgtgt aagttaaaca ttttattttg aacttggaat     2700

gttcccagtg atttcattca gcagggtatt ttctgccttg ttggcaagtg acaaaaaata     2760

tgggaagtat ttgctaccag ttggtagatg gtgcccttaa tggtagaatg aggaaaatgt     2820

ccgcaaaagc atgttttatt atctttactt ttttgggggg ttggaggggg tagcctagcc     2880

agaacatcat tgtaatctta aaacataaga tgcttttatt agatgatcaa ctaaaatagc     2940

tggaagacag tactttagaa acagatagtt gtaagattat aaaatgcaaa tgtaacttat     3000

gttttcattt ttttctctgc cttttttgtt tgtttgtttt ctcttttcca gtactgagca     3060

tctccacaaa tgtctcctaa ctcagaaaat gtttcttttc ttttcagttg agatttggtt     3120

gcattcaggg ttgtaggttg gccttgcttg ctaaccccgc cggttttacc gtgctttcat     3180

tcctgaactt tgtttatgcc tttgtttggt ttcttcgaaa ttgcagcaga ctcattgggc     3240

tacatttagt acaggaacca cgtgtgtaat gttatacaac acagtctagt aatacaatca     3300

tccctcttag agtaaaaact acctctagat tgtggtaagc ttttactgtc ccataaaaca     3360

ggagccacag taccttatga atgcaaaact gtaacttcct acagtgtttc cctacagaac     3420

attgtctttc tggtgtcctg ggctgttttg aaaaagtttc cattaataga ctttttagaa     3480

attattatta gtagcatttt ttttccagct ttgctgtctt catcactcac tctatgctca     3540

gactatgcca ctgtaaatat tcttcctaac atctttaaat cgccttttcc tcagttttca     3600

aggggaaggt catttgtaaa gcacgttagg tggttaaatc agttattgcg gttttctctt     3660

actgcaagcc tttttaatca cccccaggct gcattttatt ctatatcgcc ttttttcttc     3720

aaatctgctc caatcactca cttctctctt ataagctaat cctgcctcac accttaaatc     3780

tgtttcagtg atcaagggca gaactcattg tggccttatc tttctttgtt gtaattgttc     3840

actgtctctt tcttacagac cacttatttc tgagtagtag ttattcctct ctatggagtc     3900

atggcaggaa tcattacaca gtgcttttgt tcagagcatg gacatgttcc tagtgctgct     3960

ttgctttaac ggccacaagt ttcctccact tcctaggttt ggtatttagt taaggaatca     4020

tattaaatta accaataaca aaagagatac ttttgaagaa caaactattc cttacccatt     4080

tttgtagctc aaaaataatt tttcaagttc atgaccttat taaaatgaac ttgtgttttt     4140

ttaacaaaca tgtatgtttt attttgatag tttctttccg taagataatt gaaatattat     4200

actgtaaacc cttttctttt ctttttttga aaagtccaag aatgtactta tacaggcatt     4260

tttccccacc tatttttggc cattctcata ccacagacta aagagtgaaa tgatttgtcc     4320

attgtagctt attgtttatc agtagttctt ttgtcagctg cttacatttt ttctttcatg     4380

gttttgtgaa tcattttcag tatgtaattt ataggaacct tgtcctctgg ttatagtaga     4440

ctgtgtgccc tcctccagtg atggcattat tagacatgct ggtcatttac cctcagaaag     4500

actctcttat tagaatggtg agtgcttcag ttatagtatg tttgaatttt taaaaaattc     4560

tgttttagaa atgtatctta tgctctcatg actatgcagt ttctaaacat acacatagaa     4620

gctgagtctc tgatccaata tgtttttatt tgttccattt aatttatcac atagattggg     4680

aaggcaagct aaaagcctta aaaatgccct ttatattttg agtgatttca gcgttgaaca     4740

ctagtatact atctaaattt gctgctcact ttctttaaac tgtggcaatt aaaggcatgt     4800

ttatacatga cttaatcgtg aaatgtttgt cactcttact gcacagactt atctgcaatc     4860

ataactggtt agtttttttg ttttgttttg ttttattgtt tttaatgaaa ctggtaccat     4920

ctgtgctttc acaaaaaact tccaatgcca tttttgagaa ctaacctaac tagtcatgct     4980

aaccagaaaa tccactgggg aggaggttcc ttttgaaaca aaatgctgtt cagttagtaa     5040

ccaagttact ttgattgcaa aagcagctgt gtttctgata agtactgaac aaatgtgtgt     5100

aattttctgt gccagactta tgactttgtt ttcaagcact gtaatgtggg atggatggtt     5160

agaaacaata atatattagg gtttctgttt aaccctttca ggactgaact gtatctcctt     5220

ttgttaattt tcccctgtgt tgtgataaat gtttgccagc attcagtact gtgttggtcc     5280

agatgtaggt ttatatgctc atttttagct tatttcttgt accttgcagc atgctctacg     5340

cattcagtcc ttaaggggtt tattttacaa actgtgcgcc tgtaaggttt attagcaata     5400

agatagaaaa ttgagcaagt ttataccata attttgtaga aaaaaagaat ctgctcagtt     5460

ccatatttca tccgtgaaaa acttgcaata cgagcagttt caaggaataa ataaaaagga     5520

aatgtaaacc attgtaaaag tcttctgtcg aatgtgcctg atgcatgtat tatcgtcttt     5580

tatttcagaa tacttcataa agataaaatt aaattctata ttatagttgg tgtatttaca     5640

atcttaccat gtacatcaca tcaaagtgat agctctacta atttaatttc cttgtcaatg     5700

tttttaacta tatagtgctt taaagagatt ttttttccct gtgtaaaaaa aaaaaaaaaa     5760

aa                                                                    5762


<210>  397
<211>  7917
<212>  DNA
<213>  homo sapiens

<400>  397
agagagcaag tgagcgagag cccagccgga gggagagcca gagctaggcg caaaagaagg       60

gccagcacat tacatcatcg cttggcctgg aatcaaatgg gaaggatatg actcactcaa      120

gctagttaag ctttggctca aattctacac acactcattc cagagctctc atgttctgca      180

cctcaggagg gaattcagcc tcagtgatgt ccatgaggcc tgtcccaggc tctctatctt      240

ctctgctaca tctccacaac agacagagac agcccatgcc agcctccatg cctgggaccc      300

tgcccaaccc tacaatgcca ggatcttccg ccgtcttgat gccaatggag cgacaaatgt      360

cagtgaactc cagcatcatg gggatgcaag gtccaaatct cagcaacccc tgtgcttctc      420

cccaggtcca gccaatgcat tcagaagcca aaatgaggtt gaaggctgca ttgactcacc      480

accctgctgc catgtcaaat gggaacatga acaccatggg acacatgatg gagatgatgg      540

gctcccggca ggaccagacg ccacaccatc acatgcactc gcacccgcat cagcaccaga      600

cactgccacc ccatcaccct tacccacacc agcaccagca cccagcacac catcctcacc      660

ctcaacccca tcaccagcag aaccatccac atcaccactc ccattcccac cttcatgcac      720

acccagcaca tcaccagacc tcgccacatc cgcccctgca caccggcaac caagcacagg      780

tttcaccagc aacacaacag atgcagccaa cccagacaat acagccaccc cagcccacag      840

gggggcgccg gcgaagggtg gtagacgagg atccggacga gaggcggcgg aaatttctgg      900

aacggaaccg ggcagctgcc acccgctgca gacagaagag gaaggtctgg gtgatgtcat      960

tggaaaagaa agcagaagaa ctcacccaga caaacatgca gcttcagaat gaagtgtcta     1020

tgttgaaaaa tgaggtggcc cagctgaaac agttgttgtt aacacataaa gactgcccaa     1080

taacagccat gcagaaagaa tcacaaggat atctaagtcc agagagtagc cctcctgcta     1140

gtcctgtccc agcttgctcc cagcaacaag tcatccagca taataccatc actacttcct     1200

catcggtcag cgaggtggta ggaagctcca ccctcagcca gctcaccact cacagaacag     1260

acctgaatcc gattctttaa aatgcaccat cagacctggc ctccaagaag agctgtagcg     1320

taccatgcgt cctttctttt aagggcattt ttagaattaa ctcagacctg gaagactcct     1380

cagttcttca aagactggct ttcattttta tagttattat ggaaatgttg tcttttatac     1440

ttagttatat aagaaaaaag ggagttatgc aattaatatc tatcagcttg ggaaacgctt     1500

tggtgctttt ctccagtttt ctggtaccag ttacttgttt ataaactgaa ccttttctgt     1560

atatagccat ggtttcattc ttatcagtcc aaccctttgc ctgaaacatt gaatcttgtt     1620

aaaccacagc ttttagctaa aatgaggtat acctagatgt caagtaagac agatccaagg     1680

taactgggta ggaaatcttt tgacatctta actcatgttg agtttgtgct gtggtgtcac     1740

cagaattcca gataaacaca cagcctttcc catacctttt tttttcttac tataaaatat     1800

tataagatcc attgatgtcc aaataatacc accaagcatc tcttcacctc tcctcctctt     1860

ggtccacttg ctaatgccca gttttcttct ccatttccac tttttcttag gctccctatt     1920

tactattcat tttgacttcc ttctgtttta tttttttccc tttagcattg catgtgaata     1980

agaaaataat gtttaaagaa aaaaaaaaaa aagcaaacct ccaaaacgtg gacctaacca     2040

ttgcttcact tacacttcac ccacagctgg agttcattca actcttgctt ttcacaaaat     2100

agtaaccagg agatgtttaa tgtgcctgat ttaatgtttt taataatcac agcaaatgaa     2160

aggtggttta gttataagtg aagcatggtt gaataccagc tggggagaca ctagggaagg     2220

gagctttgta agccttgatt gcgaaagtcc aaattttgat gtggggctat aacatgacac     2280

ccttggattg cgactggttt tatacggcct gcctataacg ttgaaaatcc atgtactaca     2340

taataattca gaagggctct attcactaca cagattacat tgttcaatca tcagctgcta     2400

atagcctaag atttattttt ttttttttct taagcctatg gaaccggctt tgctgttctg     2460

gggggtgaaa atagactaac tactggagaa acaaagagag aaagaaaacc cagtgtttcc     2520

ataggggcac ttttagcctt cccacaacag ttaagcactc tttgactgct gaaggaaccc     2580

catggatgag gtgcaggcta cttcactctt tttttttctt ttttgagaca gagtctcacc     2640

tattgcccag actgaagtgc agtggtgcga tcatggatca ctgcagcagc atcctccgag     2700

ttcaagctat ccttccacct ccgcctcctg agtagctggg accacaggtt cacataacca     2760

tgcctggcta atttattttt acttttattt taaaataaaa gatgaggtct gtcttatgtt     2820

gcccaggctg gtctcaaact atcctacttc ttcctcccaa agtgttggga ttataggtgt     2880

gagccactgc acccagccta cttcactctt ctgaattatt ctgatttatt ttcaacaact     2940

tttgtgaact tgcccgtgat acaaagcaga tagtccctga accacagtcg tgcctccttg     3000

aaacaagcca ttctactgtg ctaatgtttt aatatcacat ctcacaaata acaggggtga     3060

atgtttctct ctagcaatct aggcaggtgc tggtgtttca tctccatttg aatgcttgac     3120

ctcttaatgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt tcatgggttt taaaagaaca     3180

gtattttaca aaaggtgtag cttttataag agtgcagaaa agggaaggat gtgttttttt     3240

ctctcactat agtataagaa tctattttgg agaaaaaaag aaaatatgag ggtctcgaag     3300

catgattttt atataactag tttcagtttt atctaataac ttacttttta aatcaatatt     3360

tatcaacaat ctttccttgt atgcagtgct ttcaaaagat ggttttgagt gtccagtgaa     3420

acttatgact tggatatatg gttgaagaat caaaacaaaa gcaaaaaaaa aaagcaaaaa     3480

aagaaaagag aaaaaaagaa aaaatgcaaa tggaataatt ttctattata ttttagacaa     3540

acatatcatt ttcgagtatt ttaaatactg aattcatagt tgttgttttt taaattccaa     3600

cagtaacagc tgaatggttt aatctgactg gcttcctaag aaatgtttaa gactcagctt     3660

taaaaagaag ttaacattca tatctctgtt ttgaaatcaa aaatcatatt tcaaaattct     3720

ttcctaggac catctatgtg tctcccctcc cctccacaaa aaggagaaag agtgcattaa     3780

aatgtttagt tgggtttttt aatttttaat ttttatgtta tgttttgctt tgttttaagt     3840

aaacaaaaat ttttctttct ttactgcatg catagcactt aataaaatgg atttttaaaa     3900

aatccactag taatatcaga atgtccaggg agtgactgtc actacaatga tggtttagtt     3960

tacttctgtt ccaccttttg attgaaatat ttagttgtta ggctgaaagc ctcggcagtt     4020

aagaacttgc ctgagttttc ttcgttcagc aacttgacag tttgactgat gtgcattata     4080

tatagctcaa ttatgtctgt tttttatgct aagtaggaaa accaaccaca cacattagca     4140

aaccggcctc aacatataat tagaataaac tgtcttcttg ttctactcag ggcctttagg     4200

tgtgttcatt cacggtatgg aaatacagta aatgaaagat tccaactagt tgtcagtgct     4260

tcttgaaatt ccaaacagaa agatacattg gtcaaatcca acacttggct tatcaatatt     4320

aagtctttta cctaaaggcc cagccgtcac cagacaacag aataatcaat ctgcctgaaa     4380

atccctcctc cttgtcctac actttttgcc tgtttgggag aatatctttg tactccattc     4440

tcctccctca gccagttact gggtcaccca tccatgtgtt catgaatcaa tcatcacggc     4500

ctgcagagca cctgtcctaa ggagggaaaa tcctgtcaca ctgcctctcc ccattcgtgt     4560

gtggttttct tgatcggtga gatctgtctc tgaagtcact gccagcctcc ctgggaacgt     4620

ctatagtgcc tcccctgcct tatgtgatgg gagttaacaa ctcagataag tacacctgag     4680

agcatttcta tcaggtaaac tgtcacttaa atggaggtgt ccacatctta attgtttctc     4740

cttgacacat ttctcaatcc acgaagccag gagaggtaga gtgaaaatcc cagccatgga     4800

tgaatgtact aatttgaaag ccaagtgtta agtcggatgt tttcccgtta cactactact     4860

cagccctctc ctgcggccac atcaacggat gcaagtcaca gtcttaacac agcctgtggg     4920

agacaagcag tttgtgtgct cacagtatat attatagtaa ttagggtgac ttagagcaaa     4980

tactcttcag atcctatgta gtcagtgaaa caaaatggag agcgtattct gatagaagga     5040

cgtcgacggt gaatgttctg gtggttgttg cctgttaagt aaactttagt gtgtaagttg     5100

agtttgtcat taaaatcata aaccagctgc ggtaacagac aagcctttgg ctggggagtt     5160

ttaagcctcg gtaactgcta taaaactagc catccagtta ggatagaatg tgtttctttc     5220

tggttaaaaa aaggaaaaac catctaagaa aatatatatg tatgtatgtg tgtatacagt     5280

ggaattcaaa ggaccaaagc aaaatttgaa caggaatcta ttaatttaga attttataag     5340

atatttatta ataaatgtta tttttaaaca ttccatttga acagtattct gtaggatcta     5400

cttgttttta aagtgttagt ccataataaa ctactatagt tatgtgtatt ttcatttttc     5460

agggtttcaa atggctattc tccatcattt ggtggaaatg tttgcttaga tctctgtgca     5520

tagacatttc aaggattttt attgctctgt gagttatttt ttaatcaaca ttctgaacag     5580

ttttttttaa acatttattt ctgtgtgttc atttttaaag taagctcttt catttaggaa     5640

gcagagttca gctaaaggga atcagtaact ctaactggaa cagctttctt gtagaagtgt     5700

aaaaacagct tcatctctgc ctctctccac cccaccccaa tttcctagaa agccttgcac     5760

tattcagctc ccttagtgct ttttgtccct tcccgaacaa tatgcagtag ctttaagcca     5820

ttcaagctcc attatgcagt atatctgaga agggaaagga aacaacccat ttaaatttga     5880

ataaaaccgt gcctatgcga acagtagcaa tttagaatct cttttctgct tttaaaataa     5940

tttatattta aaaattgcac tttagctttt tgatcccttt gtatttctct tattctcttt     6000

ctaacctctt ctctgtcctc aaacttgcct ttgctctcct ttacaatacc ccccacccct     6060

cctccaaggc tctgagcggc atcatttaaa atactttaca gatatttgca ccaggtacat     6120

ttatgtgcgt ccattggtag cacagctgag acctgtgtct cacatcagcc taggtgaagc     6180

ctactacaag aatgccaagg agaagagcca gtacactata tggtttatac tctttatccc     6240

tttattcata gcatgttttt taaaaatgtt atattatgca acagatgtga ggcagcagct     6300

aagctatact taagaatttt ctctcacctt ccaaaccaaa gtgtcctgaa taagccagga     6360

gacttattct tttgtgcacc ctggtgcaca tctgactgtt gtcctagcca tagactctct     6420

gaggccactg aaagaacagt ggccctatcg atttcattcc taggtctcaa aaatacaatg     6480

ttgccttgta acataattag ggacagcacc tctatttcac aattataatc taaggtagga     6540

taagacgaca cagcagcaat aaacttacaa gtaaaattca ataccaaaac aaacacaaag     6600

aaatttaaaa aacaaaaaac ctagctcatc atgttgtgaa aatgaaaaag tgaatgtcca     6660

ttcaaaatat tttactattt cttgtggagt ttttcagtga tgtaatgctt gtagccaaat     6720

tgcttaaaga gtgtttatat atttttttcc ttataaattg tctatttttt aaaaaagcta     6780

tttaaccaca gctgaagtgg ggggtaaggc caaattgcca acacttgtta aaagattaat     6840

actcttaagt ggcactctga tacctttcca acttgtcatc agaaaggaat caataattac     6900

caactgttgt atttagacca acttacaata tctagctcat tagaagccag gatctagaaa     6960

gctccttcta agccatttaa gatattctta cattgagctt catattatag aactttatag     7020

gattggatat tttacaatag aataatttag cctcaggact gagaatgtgg aagctgaata     7080

aattagcttt aaatacatca ttaaaatctt atgcacaata agctcattag attctagttt     7140

tctcctttag aataccaatg ccacagacac tacaggagat aatgaaaggt atcagttgtg     7200

ttgagtggag ggagtttaag agaaaggacc cttcccaacc agcagccagt agaaaataca     7260

acctactcac ctttttccct tctaagttct gctaaatcac atctgcctca tagagaaagg     7320

aatgttgcct ttgagaactg tcttggagaa cagataagct tgaaatgttc tctctagaga     7380

ggacataggg tttgggatcc tctgaaaagg cccagaaaaa tagctcagtt caaatacaat     7440

gttctaggac aattggaata taaatattgt ccaaaaatat aattaaaaga aaaaagttta     7500

gcactgtgta aagtaagtgt taactgagga agtcccaaaa aggtgctgtc actttaagtt     7560

ctggacttgg ggttctttgt atttgtaaac agcaaagcat ttgtgtttgt ttgtctattt     7620

gtaaagcaac caccttcctt attggaagga gaaaaaaagg ggtacataca tgtaaatact     7680

tgctgcagca tttaatatgt ttaattttgt gttaagcttt ttgttgcatc gtgaacacat     7740

ttattgttac caatggacaa tgagttcatt aagactgttc aactaggtca gatttttaca     7800

tctctttcta gcaagaagag acaagatttt gtgcatttgt acaaatgtta atatcactgc     7860

aattccaata taataaagca ctcaaatgca aataaaaaaa aaaaaaaaaa aaaaaaa        7917


<210>  398
<211>  8568
<212>  DNA
<213>  homo sapiens

<400>  398
gcgccggggt cgccagctcc tcgcccacct ccctccctgt gggagaagag gaggagggga       60

agtgactgcg gagttgatga actttgcaca tccagaaacg ccattttgat tccttttccg      120

gaacaagttt gcatctctcc tcggtctctc cctgaagccc accggtcccc aacgcatcat      180

gccagggagc caagcgtcct gcccggccgt tgctccgact gtgtgttcca ggagtggtgg      240

ctctgaggtg tgaccctgcc cacgtttggg cccagccagg ttcagccccc caataaggag      300

ggcagcttga taacacaaag aaaacagtgt caacgagtac taccaagaga agaagacaag      360

aggtcaacac agactcattt tctactccgt gtgaatgata gctacagcag gggaaagttt      420

catagtctat cagtgggtca gaaaatggag ttttatagca gaggcttctt agaagcttaa      480

acccctgtcc caatgacgtc aagttcgccc gctggcttgg aaggttcaga cctatcttcc      540

atcaacacca tgatgtcggc ggtcatgagt gtagggaagg tcacagagaa tggcgggagc      600

ccccagggga tcaagtcccc ctcgaagcct ccaggaccaa atcggattgg cagaaggaac      660

caggaaacga aagaggagaa gtcttcctat aactgccccc tgtgtgagaa gatttgcact      720

acccagcacc agctgaccat gcacattcgc cagcacaaca cagacactgg aggagccgac      780

cactcatgca gcatctgcgg aaagtcactg agctcggcca gctccctcga tcgccacatg      840

ctggtgcact ctggcgagag gccttacaag tgcactgtgt gtggccagtc atttaccacc      900

aatgggaaca tgcacagaca tatgaagatc catgagaagg accctaacag tgccacagcc      960

acagcccctc catctcctct gaaacgtagg cgattgtcct ccaagaggaa actgagtcac     1020

gatgccgagt cagagagaga agacccagca ccagctaaaa agatggtaga agacgggcag     1080

tcaggtgact tggagaagaa agctgatgaa gtctttcact gcccagtatg tttcaaggag     1140

tttgtttgca agtatggact ggagacccac atggagaccc attcagataa cccactaaga     1200

tgtgacattt gttgtgtcac ctttcgaaca catcgaggac tgctgcgtca caacgcgctt     1260

gtccacaaac aacttcccag ggatgcaatg ggcagacctt tcatacagaa caacccttca     1320

attcctgctg gcttccacga cttaggattc acggacttct cctgtaggaa gtttcctcgc     1380

atttctcagg cctggtgcga aacaaacctg cggaggtgca tcagcgagca acaccgtttt     1440

gtctgcgaca cctgtgacaa ggcgttcccc atgctctgct cactggctct gcacaagcag     1500

acccatgtgg cggcagacca gggtcaagaa aagccgcagg ccacgcccct gcctggtgac     1560

gccctggacc agaagggctt cctggccttg cttggcctgc agcacaccaa agacgtcagg     1620

cctgcccccg ccgaggagcc cctgccggat gacaaccagg caattcagct ccagacactc     1680

aagtgtcagc tacctcagga ccccggctgc accaacctgc tgagcctgtc acctttcgaa     1740

gctgcttccc taggcggttc tctcacagtt ctccccgcga ccaaggacag cataaagcac     1800

ctgtccctgc agcccttcca gaagggcttc atcatccagc ctgacagcag cattgtggtc     1860

aagcccatct ctggcgagtc ggccatcgag ctggcagaca tccagcaaat tctgaagatg     1920

gcagcctcgg ctccccctca gatcagtctt ccgcccttct ccaaggcccc tgccgcccca     1980

ctgcaggcga tcttcaagca catgccccct ctgaagccaa agcccctggt cacaccacgg     2040

acggtggtgg ccacctccac gcccccgcct ctcatcaacg cccagcaggc ttccccgggc     2100

tgtatcagcc ccagcctgcc gccaccgccc ctgaagctcc tcaaaggctc agtggaggcg     2160

gcctccaacg cccacctgct gcagtccaag tccgggaccc agccccacgc ggccacgcgg     2220

ctctccctgc agcagccgcg ggcggagctg ccgggccagc ctgagatgaa gacgcagctg     2280

gagcaggaca gcatcatcga ggccctgctg ccgctgagca tggaggccaa gatcaagcag     2340

gagatcacag agggggaact caaggccttc atgacagcgc ccggcggcaa gaagacgccc     2400

gccatgcgca aggtgctcta cccctgccgc ttctgcaacc aggtgtttgc cttctcgggg     2460

gtcttgcgtg cccacgtgcg ctcccacctg ggcatctcgc cataccagtg caacatctgc     2520

gactacatcg ccgccgacaa ggccgcgctc atccgccacc tgcgcacgca cagtggggag     2580

cggccctaca tttgcaagat ctgccactac cccttcactg tcaaagccaa ctgcgagcgg     2640

cacctgcgca agaagcacct caaggccacc cgcaaggata tcgagaagaa catcgagtat     2700

gtgagtagca gcgcggccga gctggtggac gccttctgcg ccccggacac cgtgtgccgg     2760

ctgtgcggcg aggacctcaa gcactatcgt gccctgcgca tccacatgcg cacgcactgc     2820

ggccgcggcc tgggcggggg ccacaagggc cgcaagccct tcgagtgcaa ggagtgcagc     2880

gccgcgttcg cggccaagcg caactgcatc caccacatcc tcaagcagca cctgcacgtg     2940

cccgagcagg acatcgagag ctacgtgctg gccgccgacg gcctgggccc cgcagaggcg     3000

ccggccgctg aggcgtcggg gcgcggggag gacagtggct gcgctgccct tggtgactgc     3060

aagcccctca ctgccttcct ggaaccccag aacggctttc ttcacagggg ccccacccag     3120

cctccacctc cccatgtctc gatcaagttg gagcccgcca gtagctttgc ggtggacttc     3180

aatgagcccc tggacttctc gcagaagggc ctggccctgg tccaagtgaa gcaggaaaac     3240

atctcctttc tgagcccttc ttccctggtc ccctatgact gctccatgga gcccatcgac     3300

ctgtccatcc ccaagaactt caggaaaggg gacaaggatt tggccactcc cagcgaagcc     3360

aagaagcctg aggaggaggc ggggagcagc gagcagccct ctccctgccc agcacccggc     3420

ccttctcttc ctgtaacttt ggggcccagc ggaatcctgg aaagccccat ggcccctgct     3480

ccggcggcca ccccggaacc cccagcacag cccctgcagg gccctgttca gctggcggtc     3540

ccaatctact cctcagccct ggtcagcagc cctccactcg tgggcagctc agccctcctg     3600

agtggcacag ccttgctgcg tccactgcgg cccaagcccc cgctgctttt gccaaagccc     3660

cccgtgacag aagagctgcc cccgctggcc tccattgccc agatcatctc atctgtatcc     3720

tcggccccca ccctgctgaa aaccaaggtg gcggacccag ggcccgcaag cactggcagt     3780

aacaccacgg cttcagacag cttaggaggt tctgtcccca aagccgccac caccgccacc     3840

cccgctgcca ccaccagccc aaaagagtct agtgagcctc ccgctccagc cagcagccca     3900

gaggctgcct ctcccaccga gcagggccca gcgggcacgt cgaagaagag gggccggaaa     3960

agggggatga ggagccgacc ccgcgccaac agcggcgggg tggacctgga ctccagcggg     4020

gagtttgcca gcatcgagaa gatgctggcc accacagaca ccaacaagtt cagtccgttt     4080

ctgcagacag cggaggacaa cactcaggat gaggtggccg gagcccctgc cgaccaccat     4140

gggcccagtg atgaagagca gggcagtccc ccagaagaca agctgctgag ggccaagcgg     4200

aactcgtaca ccaactgcct gcagaagatc acctgtcccc actgtccccg ggttttccct     4260

tgggccagct ccctacagag gcacatgctc acacacactg acagtcagtc ggatgcggag     4320

actgcagccg ccgcgggcga agtgctagac ctcacctcac gggacagaga gcagccgtcg     4380

gagggcgcca ctgagctccg ccaggtcgca ggggatgcgc ctgtggagca ggccacggcg     4440

gaaacggcct cgccggtgca ccgggaagag cacgggcgtg gggagagcca tgagccggag     4500

gaggagcatg gcactgagga gagcactggg gacgccgacg gcgcggaaga ggacgcgtcg     4560

agcaaccaga gcctggacct ggacttcgcc accaagctca tggacttcaa gctggcggag     4620

ggcgacggcg aggcaggcgc cgggggcgcg gcctcgcagg agcagaagct cgcctgcgac     4680

acctgtggga agagcttcaa gttcctgggc accctgagcc gccaccggaa ggcgcacggc     4740

cgccaggagc ccaaggacga gaagggagat ggcgccagca ctgcagagga ggggccccag     4800

cccgcccctg aacaggagga gaagcccccc gagaccccgg cagaggtggt ggagtcggcc     4860

ccgggtgccg gggaggcccc ggcggaaaag ctcgcggagg agacggaggg cccctccgac     4920

ggggagagcg cggccgagaa aaggtcctca gagaagagcg acgatgacaa gaaaccaaag     4980

acagactccc ccaaaagcgt ggccagcaag gcagacaaga ggaagaaggt ctgcagcgtg     5040

tgcaacaagc ggttctggtc gctgcaggac ctgacccggc acatgcgctc ccacacaggg     5100

gaaaggccat acaaatgtca gacctgcgag cgaaccttca ccttgaagca cagcctggtt     5160

cgccaccagc ggatccacca gaaagccagg catgccaaac accacgggaa ggacagcgac     5220

aaggaagagc ggggtgagga ggacagcgag aatgagtcca cccacagcgg caacaacgcc     5280

gtctcagaga acgaggctga gctggctccc aatgccagca accacatggc tgtcacccgg     5340

agccggaagg agggcttggc cagtgccacc aaggactgca gccacaggga ggagaaggtc     5400

acggcagggt ggccgtctga gcctggccag ggtgacctta acccagagag cccggcggcc     5460

ctggggcagg acctgctgga gccgcgcagc aagaggcctg cccacccaat cctggccaca     5520

gctgatggcg cctcccagct cgtggggatg gagtgacagc ctcagtcccc ctcagcacag     5580

acaaaagcca gcagagcaaa gcgtctatac ttcatggggt ttcctcagtg ccctttggct     5640

gttgaggagt gagagagaga gagagagaga gagagagaga gagagagaga gacaagcagg     5700

agcgtggctg ctcgctcagt gccatagcct taccgcagcc tgcgcgggag gccacagccc     5760

gtgccgattc cagtgcctta actacttacc ggatccctcc atattatcat gggtgttgta     5820

tttttccaaa atgacttctt aaacaaaaca aatattataa tgaattgtct ggagaggacc     5880

tcttcatttg agcattagcg ttattttgta ttggtgtgtg tgagcttgtt cttgtgaatc     5940

tgtgatagca ccgtttgttc tgtgagctgg aaacagaagg aaaaaacata cccttgggta     6000

cccatagcca ataactggaa gaaaatgatg tgaatttcat gtaaatgacc agaggaaaga     6060

tggataagat gataatttct taaatagaca ttttcctttt ttctttgtgc ttcatggtgg     6120

agctgtcatc tggtccttgg tattacagga tgtggttgat gaaggtttcc aatatggttt     6180

caggccaaaa ccagggaaga ttctagcttc agcctcatgt ccatttccag tctgtcagca     6240

ttagacatgg tcactgttca agtttcaaga catccattct taactataga gaagagttac     6300

tcccctggcg tcttaaccta tggaaaacat gcacggatag gatatatttg attgcctcct     6360

cttccctttc agtatatgta ttattaatat tattattatt attattatta ttagttcatc     6420

agtttgctgt tctctgcagt gagcagaatc aaatgggcaa tatttgtcct gggagacctg     6480

tgccgcaccc aggtccccgt gttaacgtgt gcctgcggtt gtggttggca ccctcgggtg     6540

gtagctcttc tactgtaatg agacaagcct ttcttctgtc actgcagaat ttagaagggg     6600

ccgtgagcag tcttcccaag catggtccag gagcagctca gagagggtgg agtgaggatg     6660

catgcatcca gggaacaggc atcaagaagc cagggccgtg cctggagcac tgcagagatg     6720

actttggaga aagcaaagca gtgacccagt gaccaggcac attactcgtg agcgaggtat     6780

tcccagtctt cctgctaagc ctaatccaag ccttacccag ctgtgctact gtcatttgca     6840

aagcaaggaa atactactac tggtaataaa actacacatg caagatgtca gataagaaat     6900

aggtttatat ttaccttcct gcgatgtggg gttggtgctt gaagataaat gtgctgtttc     6960

tagtttctta aatagcccac acccctggat gcaaaaaggc agggttattt ttacccatga     7020

gcatcctgtg caggcaatag acttccctca ctgtctccgc ctgcagggag gagaatgtac     7080

cccactgcac ctgagctcct ggtccctcag ccaagacctc aggggtcccc agccagcctg     7140

ctgctgggga cccctgtgct tgctgcagtg tatggagcct cttgccttcc cctggggagg     7200

cacccctgta ccccagcttc cttcccctgg ccttttctgg ccccagtgct cctcctttac     7260

atagacttgt tcacacagaa acgtgcacgc ccccttttct ccgccacttc accagtttct     7320

gaaatccaac ctcccagact tcacaggaag atagatattc ttgagataat gaaaagtgat     7380

atcttcgcat acgaaaggaa aaaaggttga ggtatatatg atttttaact gtattagggg     7440

tgtatgaacc agtttaaaaa cgaggtttta tttactgtag agatgaatgc aaatcagaac     7500

caatgatccc ttggcctact tagttaaaac cagttcatac atcccttagg gtttttatta     7560

ttattattat tattattaca gttgttattg ttgtttttgt tgttattatt atttggggtt     7620

tcttgtgttt tttctttgcg actctccaca ctaaacttgc aatattgtgg ggagaagctg     7680

tgactaaact ctacgctgcg gtgagatgta gcagtaatca gctcccagcg acgtgtgtag     7740

ctggggctgc cgctcgcaat aatcactatt gatttaaagc tttacttagc cttgatctgt     7800

accctcgtag tcaataaggt cttgccacat tttattagtg aggtggagaa acgtattatt     7860

tgtttgttgt ttttgccctt cccccacccc ccaatattaa actgtgaaat ttgtgatttg     7920

tttaaactct gggtgaatca tagcttagtt tgcatgtcca gctaatttgt ttctatacat     7980

tttgtttgat tctctttctc cttctctcag ggcttttaca aaaaaatata tatatatgga     8040

tcttctgaaa agttttttga ggtgcaagtt ttttctcttt tttttttttt tttttttttc     8100

tcattgatta atggacatga tgctgagatt caatcactac atgaaacacc tggctgtgaa     8160

aacaaaacaa cccagagggc tgtgttccaa gcagcgctgg ggaagctacg taacagtcgg     8220

atgccagttt tggaagattc accatgcgtt ctgaccctct gttcgtctct ttcctctcct     8280

ctttcttcaa gaaggaaatt gatcctagtg atttcagccc atgcattaaa caggaaacaa     8340

taataaattt gtagaattca tatttttcta aagggaactt aaaaactgct gctacatgtt     8400

atgtacaaaa ctggtttatg ccacatgaac agagaatcac aagtttggtt ttggtacttt     8460

ttgttcctct ttgtattcag ttgtatagaa cttccaaatt cagaatgaga agaaagctgt     8520

tctgtatcaa accatttaag caataaatgt tatattttaa aagctgca                  8568


<210>  399
<211>  1105
<212>  DNA
<213>  homo sapiens

<400>  399
attgcaactt ggtctcacag tggcttaggc cagggtggga gcagtgaacg gagtcacaaa       60

agaaattttt cagctgtcct ctctgacacc accccggcct gcctctttgt tgccatgaga      120

gctgcctacc tcttcctgct attcctgcct gcaggcttgc tggctcaggg ccagtatgac      180

ctggacccgc tgccgccgtt ccctgaccac gtccagtaca cccactatag cgaccagatc      240

gacaacccag actactatga ttatcaagag gtgactcctc ggccctccga ggaacagttc      300

cagttccagt cccagcagca agtccaacag gaagtcatcc cagccccaac cccagaacca      360

ggaaatgcag agctggagcc cacagagcct gggcctcttg actgccgtga ggaacagtac      420

ccgtgcaccc gcctctactc catacacagg ccttgcaaac agtgtctcaa cgaggtctgc      480

ttctacagcc tccgccgtgt gtacgtcatt aacaaggaga tctgtgttcg tacagtgtgt      540

gcccatgagg agctcctccg agctgacctc tgtcgggaca agttctccaa atgtggcgtg      600

atggccagca gcggcctgtg ccaatccgtg gcggcctcct gtgccaggag ctgtgggagc      660

tgctagggtg gtgctggcat cctgagtcct ggccctcctg ggatctgggg ccctcgggcc      720

ctgcctgacc tggtgctttt ttccccatcc ccatgttcct tttattctgt aaaaagttag      780

tggactgcag ccctgggggt tgcaggctgc ggtgcctcag gcccctcctt cagcctgtgg      840

ccacctctgg ggcacaatgg gggctcccca ctgcccagtc tgcccctcgg gttgggggag      900

tatcccaggc ctctctgtgg gacctgggcc cctgacgggc cttctcagcc cgttttgagg      960

acagacagtc ccccgaggta ggctacatcc ccccacccca gctggtctgc ttggatttcc     1020

tacagccccc gtgggcatgg accaccttta ttttatacaa aattaaaaac aagtttttac     1080

aaaaaaaaaa aaaaaaaaaa aaaaa                                           1105


<210>  400
<211>  6723
<212>  DNA
<213>  homo sapiens

<400>  400
atggaactat ctcctgagtg ctgcaagttg taacgggcac cgctgagcct gtttcccttt       60

ggagcacttc ttatctagaa gcagtgttta gtttcttcca aactgggcca cttcgtccac      120

ctactctgtt ctgagtaagg aaacagcctc caagcatcag cagagcccag atgagcacgg      180

gccgcggagc cgcttagcag tctcccggga cccagctccg gaggagccgc aagcatgcac      240

cctgggttgt ggctgctcct ggttacgttg tgcctgaccg aggaactggc agcagcggga      300

gagaagtctt atggaaagcc atgtgggggc caggactgca gtgggagctg tcagtgtttt      360

cctgagaaag gagcgagagg acgacctgga ccaattggaa ttcaaggccc aacaggtcct      420

caaggattca ctggctctac tggtttatcg ggattgaaag gagaaagggg tttcccaggc      480

cttctgggac cttatggacc aaaaggagat aagggtccca tgggagttcc tggctttctt      540

ggcatcaatg ggattccggg ccaccctgga caaccaggcc ccagaggccc acctggtctg      600

gatggctgta atggaactca aggagctgtt ggatttccag gccctgatgg ctatcctggg      660

cttctcggac cacccgggct tcctggtcag aaaggatcaa aaggtgaccc tgtccttgct      720

ccaggtagtt tcaaaggaat gaagggggat cctgggctgc ctggactgga tggaatcact      780

ggcccacaag gagcacccgg atttcctgga gctgtaggac ctgcaggacc accaggatta      840

caaggtcctc cagggcctcc tggtcctctt ggtcctgatg ggaatatggg gctaggtttt      900

caaggagaga aaggagtcaa gggggatgtt ggcctccctg gcccagcagg acctccacca      960

tctactggag agctggaatt catgggattc cccaaaggga agaaaggatc caagggtgaa     1020

ccagggccta agggttttcc aggcataagt ggccctccag gcttcccggg ccttggaact     1080

actggagaaa agggagaaaa gggagaaaag ggaatccctg gtttgccagg acctaggggt     1140

cccatgggtt cagaaggagt ccaaggccct ccagggcaac agggcaagaa agggaccctg     1200

ggatttcctg ggcttaatgg attccaagga attgagggtc aaaagggtga cattggcctg     1260

ccaggcccag atgttttcat cgatatagat ggtgctgtga tctcaggtaa tcctggagat     1320

cctggtgtac ctggcctccc aggccttaaa ggagatgaag gcatccaagg cctacgtggc     1380

ccttctggtg tccctggatt gccagcatta tcaggtgtcc caggagccct agggcctcag     1440

ggatttccag ggctgaaggg ggaccaagga aacccaggcc gtaccacaat tggagcagct     1500

ggcctccctg gcagagatgg tttgccaggc ccaccaggtc caccaggccc acctagtcca     1560

gaatttgaga ctgaaactct acacaacaaa gagtcagggt tccctggtct ccgaggagaa     1620

caaggtccaa aaggaaacct aggcctcaaa ggaataaaag gagactcagg tttctgtgct     1680

tgtgacggtg gtgttcccaa cactggacca cccggggaac caggcccacc tggtccatgg     1740

ggtctcatag gccttccagg ccttaaagga gccagaggag atcgaggctc tgggggtgca     1800

cagggcccag caggggctcc aggcttagtt gggcctctgg gtccttcagg acccaaagga     1860

aagaaggggg aaccaattct cagtacaatc caaggaatgc caggagatcg gggtgattct     1920

ggctcccagg gcttccgtgg tgtaatagga gaaccaggca aggacggagt accaggttta     1980

ccaggtctgc caggccttcc gggtgatggt ggacagggct tcccaggtga aaaggggtta     2040

cctggacttc ctggtgaaaa aggccatcct ggtccacctg gcctcccagg aaatgggtta     2100

ccaggacttc ctggaccccg tgggcttcct ggagataaag gcaaggatgg attaccggga     2160

caacaaggcc ttcccggatc taagggaatc accctgccct gtattattcc tgggtcatac     2220

ggtccatcag gatttccagg cactcccgga ttcccaggcc ctaaagggtc tcgaggcctc     2280

cctgggaccc caggccagcc tgggtcaagt ggaagtaaag gagagccagg gagtccagga     2340

ttggttcatc ttcctgaatt accaggattt cctggacctc gtggggagaa gggcttgcct     2400

gggtttcctg ggctccctgg aaaagatggc ttgcctggga tgattggcag tccaggctta     2460

cctggttcca agggagccac tggtgacatc tttggtgctg aaaatggtgc tccgggggaa     2520

caaggcctac aaggattaac agggcacaaa ggatttcttg gagactctgg ccttccagga     2580

ctcaagggtg tgcacgggaa gcctggctta ctaggcccca aaggtgagcg gggcagccct     2640

gggacaccag gacaggtggg acagccaggc accccaggat ctagtggtcc atatggcatc     2700

aagggcaaat ctgggctccc aggagcacca ggcttcccag gcatctcagg acatcctgga     2760

aagaaaggaa caagaggcaa gaaaggtcct cctggatcaa ttgtaaagaa agggctgcca     2820

gggctaaaag gccttcctgg aaatccaggc ctagtaggac tgaaaggaag cccaggctct     2880

ccaggggtcg ctgggttgcc agccctctct ggacccaagg gagagaaggg gtctgttgga     2940

ttcgtaggtt ttccaggaat accaggtctg cctggtattc ctggaacaag aggattaaaa     3000

ggaattccag gatcaactgg aaaaatggga ccatctggac gtgctggtac tcctggtgaa     3060

aagggagaca gaggcaatcc ggggccagtc ggaataccta gtccaagacg tccaatgtca     3120

aacctttggc tcaaaggaga caaaggctct caaggctcag ccggatccaa tggatttcct     3180

gggccaagag gtgacaaagg agaggctggt cgacctggac caccaggcct acctggagct     3240

cctggcctcc caggcattat caaaggagtt agtggaaagc cagggccccc tggcttcatg     3300

ggaatccggg gcttacctgg cctgaagggg tcctctggga tcacaggttt cccaggaatg     3360

ccaggagaaa gtggttcaca aggtatcaga gggtcgcctg gactcccagg agcatctggt     3420

ctcccaggcc tgaaaggaga caacggccag acagttgaaa tttccggtag cccaggaccc     3480

aagggacagc ctggcgaatc tggttttaaa ggcacaaaag gaagagatgg actaataggc     3540

aatataggct tccctggaaa caaaggtgaa gatggaaaag ttggtgtttc tggagatgtt     3600

ggccttcctg gagctccagg atttccagga gttgccggca tgagaggaga accaggactt     3660

ccaggttctt ctggtcacca aggggcaatt gggcctctag gatcccccgg attaatagga     3720

cccaaaggct tccctggatt tcctggttta catggactga atgggcttcc gggcaccaag     3780

ggtacccatg gcactccagg acctagtatc accggtgtgc ctgggcctgc tggtctccct     3840

ggacccaaag gagaaaaagg atatccagga attggcatcg gagctccagg gaagccgggc     3900

ctgagagggc aaaaaggtga tcgaggtttc ccaggtctcc agggccctgc tggtctcccc     3960

ggtgccccag gcatctcctt gccctcactc atagcaggac agcctggtga ccccgggcga     4020

ccaggcctag atggagaacg aggccgccca ggccccgctg gacccccagg tccccctggg     4080

ccatcctcga atcaaggcga caccggagac cctggcttcc ctggaattcc tggacctaaa     4140

gggcctaagg gagaccaagg aattccaggt ttttctggcc tccctggaga gctaggactg     4200

aaaggcatga gaggtgagcc tggcttcatg gggactccag gcaaggttgg gccacctgga     4260

gacccaggat ttcccggaat gaaggggaag gcagggccaa gaggctcttc tggcctccaa     4320

ggtgatcctg gacaaacacc aactgcagaa gctgtccagg ttcctcctgg acccttgggt     4380

ctaccaggga tcgatggcat ccctggcctc actggggacc ctggggctca aggccctgta     4440

ggcctacaag gctccaaagg tttacctggc atccccggta aagatggccc cagtgggctc     4500

ccaggcccac ctggggctct tggtgatcct ggtctgcctg gactgcaagg ccctccagga     4560

tttgaaggag ctccagggca gcaaggcccc ttcgggatgc ctggaatgcc tggccagagc     4620

atgagagtgg gctacacgtt ggtaaagcac agccagtcgg aacaggtgcc cccgtgtccc     4680

atcgggatga gccagctgtg ggtggggtac agcttactgt ttgtggaggg gcaagagaaa     4740

gcccacaacc aggacctggg ctttgctggc tcctgtctgc cccgcttcag caccatgccc     4800

ttcatctact gcaacatcaa cgaggtgtgc cactatgcca ggcgcaatga taaatcttac     4860

tggctctcca ctaccgcccc tatccccatg atgcccgtca gccagaccca gattccccag     4920

tacatcagcc gctgctctgt gtgtgaggca ccctcgcaag ccattgctgt gcacagccag     4980

gacatcacca tcccgcagtg ccccctgggc tggcgcagcc tctggattgg gtactctttc     5040

ctcatgcaca ctgccgctgg tgccgagggt ggaggccagt ccctggtctc acctggctcc     5100

tgcctagagg actttcgggc cactcctttc atcgaatgca gtggtgcccg aggcacctgc     5160

cactactttg caaacaagta cagtttctgg ttgaccacag tggaggagag gcagcagttt     5220

ggggagttgc ctgtgtctga aacgctgaaa gctgggcagc tccacactcg agtcagtcgc     5280

tgccaggtgt gtatgaaaag cctgtagggt ggcacctgcc actctgcccc ttgccctccc     5340

ctgcccctca caacagtcac ctcacaaacc tgaatggtct gaagaaggaa ggcctgagcc     5400

cctttgcctg tcaagttgta cattggagtc tcatttgggc tagactaccg gacactcgtc     5460

accccagccc tcgggtccat agagatgagc ccaccctgct gagatctgct gtcctgtttc     5520

tgtcaagctg gtgctactgt ttgatttgga tgattgtgtg actattcatg gctacctcag     5580

aaagatttga tgggccacaa ctgtcttaga ctgctagctt tctccttacc gtcttgatcg     5640

gaaagctctt cctaatcgct aatcagtcat ttcttcatgt acagaggtca gcacacatta     5700

tttggcttaa accagaaccc agtgtttcca cacttaaatt ctctaaccga atattcatgg     5760

atggctcaag tctgcacaga gcaagtcctc actcttcaag gaggcccact gtgtctaggc     5820

aggcaagaga attgaaatga ggtgccaccc agtagcccag agtgagcttt agctctctct     5880

agaatgagca agactgggcc ccacatggct tagagaggct tgaaggccag cagctgggtt     5940

gggggtggtg gtcattaatg gcatatggtc ctagacaaac catctcctcc ttgccggctc     6000

cccctccagc cagagacaga ggatgtggcc tggttcaaag taaagcagag gatgcaacaa     6060

atgtggccaa gcctatcaaa ggaaatgaga atgacagcct tttttcctgg gccagaagta     6120

gaggggtggg tgcgtaagga tgtgtgagtt ttgcttttga ctccaggaac aaaaaggtaa     6180

atcccacatc ccagtttctc agaagtccct gtttattcca aatgccatcc agatgtgtgc     6240

aatgtggcaa actgaagctg cacagtgttg gtttccttgt attctgagga tgttaaagac     6300

tttgttaaat ggttatccaa ttgctctttc acaggtagcc tattaaacta ttttaatatg     6360

tttttttaaa cctcataaaa atctagcaca ctcttctctt gagcagttag cagacctaaa     6420

gcaagcctga attggctatg cagtacattg tattctgttt gggggaattt gttttagcca     6480

ttttctttaa ttaccagttt tccagaacac tcttagctat gttgacatga ggcagttcct     6540

tccaggtgat tctgtttcct taagtattat ataaactgtg ccaatacaga caaagcataa     6600

tcaatataat ctgaattatt gttatcttta cctcctgagt aataagcatg gtgtcagttt     6660

tgtacatagc aaataaaata aatgaaatct gaacatgtga aaaaaaaaaa aaaaaaaaaa     6720

aaa                                                                   6723


<210>  401
<211>  4494
<212>  DNA
<213>  homo sapiens

<400>  401
ggcccggccg gactgagttc gctgctgtcc cggttcctct cgagtcggct ccaactgcca       60

gcccgggttg gcgccatgta cgccgtgtac aaacaggcgc atccgcccac cggtctggag      120

ttctccatgt actgcaactt cttcaacaac agcgagcgca acctggtagt ggccgggacc      180

tcgcagctct acgtgtaccg cctcaaccgc gacgccgagg ctctgaccaa gaatgacagg      240

agcacagagg ggaaggccca ccgggagaag ctcgagcttg ctgcctcctt ctccttcttt      300

ggcaacgtca tgtccatggc cagcgtgcag ctggcaggag ccaagcggga tgccctgctc      360

ctaagcttca aggatgccaa gctgtctgtg gtggagtacg acccgggcac ccatgacctg      420

aagaccctgt cactgcacta ctttgaggag cctgagcttc gggacgggtt tgtgcagaat      480

gtacacacgc cgcgagtgcg ggtggacccc gacgggcgct gtgcagccat gcttgtctac      540

ggcacgcggc tggtggtcct gcccttccgc agggagagcc tggctgagga gcacgagggg      600

ctcgtgggtg aggggcagag gtccagcttc ctgcccagct acatcatcga cgtgcgggcc      660

ctagacgaga agctgctcaa catcatcgac ctgcagttcc tgcatggcta ctacgagcct      720

accctcctca tcctgtttga gcccaaccag acctggcctg ggcgcgtggc cgtgcggcag      780

gacacgtgct ccattgtggc catctcactg aacatcacgc agaaggtgca ccccgtcatc      840

tggtccctca ccagcctgcc ctttgactgc acccaggctc tggctgtgcc caagcccata      900

ggtggggtgg tggtgtttgc cgtcaactcg ctgttgtacc tgaaccagag cgtccccccg      960

tatggcgtgg ctctcaacag cctcaccaca ggaaccacgg ctttcccgct tcgcacccag     1020

gagggtgtgc ggatcaccct ggactgcgcc caggccacct tcatctccta cgacaagatg     1080

gtcatctccc tcaagggcgg cgagatctac gtgctgaccc tcatcaccga cggcatgcgc     1140

agtgtccgag cgttccactt tgacaaggcg gccgccagcg tcctcaccac cagcatggtc     1200

accatggagc ccgggtacct gttcctgggt tctcgcctgg gcaattccct cctcctcaag     1260

tacacggaga agctgcagga gcccccggcc agtgctgtcc gtgaggctgc cgacaaggaa     1320

gagcctccct caaagaagaa gcgagtggat gcgacggccg gctggtcagc tgcgggtaag     1380

tcggtgccgc aggatgaggt ggacgagatt gaagtgtacg gcagcgaggc ccagtcggga     1440

acacagctgg ccacctactc ctttgaggtg tgtgacagca tcctgaacat tggaccctgt     1500

gccaatgccg ccgtgggcga gcctgccttc ctctctgaag agtttcagaa cagccccgag     1560

ccggacctgg agattgtggt ttgctccggc cacgggaaga acggggcttt gtcggtgctg     1620

cagaagagca tccggcccca ggtggtgaca acctttgagc ttcccggctg ctatgacatg     1680

tggacagtca tcgccccggt gcgtaaggag gaggaggaca atcccaaggg ggagggcaca     1740

gagcaggaac ccagcaccac ccctgaagca gacgacgacg gccgcagaca cggattcctg     1800

attctgagcc gggaagactc caccatgatc ctgcagacgg ggcaggagat catggagctg     1860

gacaccagtg gcttcgccac tcagggcccc acggtctttg ctgggaacat cggggacaac     1920

cgctacattg tccaagtgtc accactgggc atccgcctgc tggaaggagt gaatcagctg     1980

cacttcatcc ccgtggacct gggcgccccc atcgtgcagt gcgccgtggc cgacccctat     2040

gtggtcatca tgagtgccga gggccacgtc accatgttcc tgctgaagag tgactcctac     2100

ggtggccgcc accaccgcct ggcgctgcac aagcccccgc tgcaccatca gtccaaggtg     2160

attacgctgt gcctgtaccg agacctcagc ggcatgttca ccactgagag ccgcctgggt     2220

ggggcccgtg acgagctcgg gggccgcagt ggcccggagg ccgagggcct gggctcagag     2280

actagcccca cagtggatga cgaggaggag atgctgtatg gggattcggg ctccctcttc     2340

agccccagca aggaggaggc ccgaagaagc agccagcccc ctgctgaccg ggaccctgca     2400

cccttccggg cagagcctac ccactggtgc ctgctggtgc gggagaatgg caccatggag     2460

atctaccagc ttcccgactg gcggctggtg ttcctggtga agaacttccc tgtggggcag     2520

cgggtccttg tggacagctc ctttggacag cccactacac agggcgaggc ccgcagggag     2580

gaggccacgc gccaggggga gctgcccctc gtcaaggagg tgctgctggt ggcgctgggc     2640

agccgccaga gcaggcccta cctgctggtg catgtggacc aagagctgct tatctacgag     2700

gccttccccc acgactctca gctcggccag ggcaatctca aagtccgctt taagaaggtc     2760

cctcacaaca tcaacttccg tgagaagaag ccaaagccat ccaagaagaa agcagaaggt     2820

ggcggcgcag aggagggggc tggggcccgg ggccgcgtgg cgcgtttccg ctacttcgag     2880

gatatttatg gctactcagg ggtcttcatc tgcggcccct cccctcactg gctcttggtg     2940

accggccgag gggctctgcg gctacacccc atggccatcg acggcccggt cgactctttc     3000

gctccattcc acaatgtcaa ctgtccccgc ggcttcctgt acttcaacag acagggcgag     3060

ctgaggatca gtgtcctgcc tgcctacctg tcctatgatg ccccatggcc tgtcaggaag     3120

atcccgctgc gctgcacggc ccactatgtg gcttaccacg tggagtctaa ggtgtatgct     3180

gtggccacca gcaccaacac gccgtgtgcc cgcatcccac gcatgactgg cgaggagaag     3240

gagtttgaga ccatcgagag agatgagcgg tacatccacc cccagcagga ggccttctcc     3300

atccagctca tctccccggt cagctgggag gctattccca atgccaggat cgagctgcag     3360

gagtgggagc atgtgacctg catgaagaca gtgtctctgc gcagtgagga gaccgtgtcg     3420

ggcctcaaag gctacgtggc cgccgggacc tgcctcatgc agggggagga ggtcacgtgc     3480

cgagggcgga tcttgatcat ggatgtgatt gaggtggtgc ccgagcctgg ccagcccttg     3540

accaagaaca agttcaaagt cctttacgag aaggagcaga aggggcccgt gaccgccctg     3600

tgccactgca atggccacct ggtgtcggcc atcggccaga agattttcct gtggagcctg     3660

cgggccagcg agctgacggg catggccttc atcgacacgc agctctacat acaccagatg     3720

atcagcgtca agaacttcat cctggcagcc gacgtcatga agagcatttc gctgctgcgc     3780

taccaggagg aaagcaagac gctgagcctg gtgtcgcggg atgccaagcc cctggaggtg     3840

tacagcgtgg acttcatggt ggacaatgcc cagctgggtt ttctggtgtc tgaccgcgac     3900

cgcaacctca tggtgtacat gtacctgccc gaagccaagg agagtttcgg gggcatgcgc     3960

ctgctgcgtc gggcagactt ccacgtgggt gcccacgtga acacgttctg gaggaccccg     4020

tgccgggggg ccactgaagg gctcagcaaa aagtcggtcg tgtgggagaa taagcacatc     4080

acgtggtttg ccaccctgga cggcggcatc gggctgctgc tgcccatgca ggagaagacc     4140

taccggcggc tgctgatgct gcagaacgcg ctgaccacca tgctgccaca ccacgccggc     4200

ctcaaccccc gcgccttccg gatgctgcac gtggaccgcc gcaccctcca gaatgccgtg     4260

cgcaacgtgc tggatgggga gctgctcaac cgctacctgt acctgagcac catggagcgc     4320

agcgagctag ccaagaagat cggcaccaca ccagacataa tcctggacga cttgctggag     4380

acggaccgcg tcaccgccca cttctagccc cgtggatgcc gtcaccacca gcacacggaa     4440

ctacctccca cccccttttt gtacaaaaca caaggaaaaa cattttttgc ttga           4494


<210>  402
<211>  6630
<212>  DNA
<213>  homo sapiens

<400>  402
ctcggaagtg acgcaagcgc ccccccaccg ccgctagatc cgctgctgct gccgcggcgg       60

gcagacctgc aggaggcggc ggcggcggcg gcggccgagg ctgaaggaag atggcggacg      120

gcgtggacca catagacatt tacgcggatg tcggcgaaga gttcaaccag gaagctgaat      180

atggtgggca tgatcagata gatttgtatg acgatgtcat atctccatct gcaaataatg      240

gagatgcccc agaagaccga gattacatgg atactctccc accaactgtt ggtgatgatg      300

tgggtaaagg agcagcacca aatgttgtct atacatatac tggaaagaga attgcattat      360

atattggaaa tctaacatgg tggacaacag atgaagactt aactgaagca gttcattctt      420

tgggagtaaa tgatattttg gagataaaat tttttgaaaa tcgggcaaat ggccagtcaa      480

aggggtttgc ccttgttggt gttggatctg aagcatcttc aaaaaagtta atggatctgt      540

tacctaaaag agaacttcat ggtcagaatc ctgttgtaac tccatgcaat aaacagttcc      600

tgagtcaatt tgaaatgcag tccaggaaaa ctacacaatc aggacaaatg tctggggaag      660

gtaaagctgg tcctccagga ggcagttccc gtgcagcatt tccacaaggt ggtagaggac      720

ggggccgttt tccaggggct gttcctggtg gggacagatt tcctgggcca gcaggaccag      780

gagggccacc cccacctttt ccagctggac agactccacc acgtccaccc ttaggtcctc      840

caggcccacc tggtccacca ggtcctccac ctcctggtca ggttctgcct cctcctctag      900

ctgggcctcc taatcgagga gatcgccctc caccaccagt tctttttcct ggacaacctt      960

ttgggcagcc tccattgggt ccacttcctc ctggccctcc acctccagtt ccaggctacg     1020

gcccccctcc tggcccacca cctccacaac agggaccacc tccacctcca ggcccctttc     1080

cacctcgtcc acccggtcca cttgggccac cccttacact agctcctcct ccgcatcttc     1140

ctggaccacc tccaggtgcc ccaccgccag ctccgcatgt gaacccagct ttctttcctc     1200

caccaactaa cagtggcatg cctacatcag atagccgagg tccaccacca acagatccat     1260

atgggcgacc tccaccatat gataggggtg actatggccc ccctggaagg gaaatggata     1320

ctgcaagaac gccattgagt gaagctgaat ttgaagaaat catgaataga aatagggcaa     1380

tctcaagcag tgctatttcg agagctgtgt ctgatgccag tgctggtgat tatgggagtg     1440

ctattgagac actggtaact gcaatttctt taattaaaca atccaaagta tctgctgatg     1500

atcgttgcaa agttcttatt agttctttgc aagattgcct tcatggaatt gagtccaagt     1560

cttatggttc tggatcaaga cgtgaacgat caagagagag ggaccatagt agatcacgag     1620

aaaagagtcg acgtcataaa tcccgtagta gagaccgtca tgacgattat tacagagaga     1680

gaagcagaga acgagagagg caccgggatc gtgaccgaga ccgtgaccga gagcgtgacc     1740

gagagcgcga atatcgtcat cgttagaagc tgaaggaaga ggatcacctt ccaagacaaa     1800

acagtcttca tgggggaaaa atgacgcttg tccagcagtt tgcttcttgt gattgaactg     1860

aacctgtaag gattcatgga taaaatgaac aggaatagat ctgaataaag caaatctgca     1920

taaatggtaa ccagtagctc tacttttatt ttttatgttg cttaactgtt ttatttgaag     1980

gaaacctgtg tgatttaaaa agttatagct tttgcaactt tattactggt tatatacatt     2040

tggccattat gatgtgcaag caattggaaa aaaagtcaag taaatgcttg tttttgtagt     2100

agtttgttct tgttaaaaat gtttatatga taatgtctgt aaacagcatc actttgatta     2160

caatagatgt agtgttgtaa taaactgttt aatggggctg atgtgtaaag ctgttcaagt     2220

tatttgatgt ttacacctca gggaaagtct tgtgttcagc aatatctaaa gataatgtta     2280

ctatgacaac atttttactg tcctttaaag cattgcaata gcgtttttgg atatgcctca     2340

atctaatctt gcgttcagtg aattaaacat agtaattaag tgtcttttgc ccttgatttt     2400

gatattagaa taggtgatta catggatatt taatatttct atattctgct tttctagctg     2460

tttttaccta gttagcttgt gactttgctg aatggtatgt aaacttgtaa aaatagagat     2520

ttgacagaca tagcaatcta gtcaatgtgt aaggggtcaa aaaaacagag gttttaacac     2580

ataagtaaaa acccgtacat atttgatgtg taatgcaggt taattacaac acagatgtac     2640

cgaaacactt aattgtgaac cgctaacatt gaagaaattt tgacaattcc gatttgatgc     2700

tgcaattact tgctgttttt attgatctta tggtttattt cttaagccat agtcagtgta     2760

aatacagccc tgcagcaggt aaatgtgagt aaagagagcc ttatattttc caattggtat     2820

aaatttttga aggatgtgat gttcattaac attcggttgt attccccagt atttgtaatg     2880

ggaaattaca gataaaccgt gtctgcacag tttaaggaat actatgtata ttcatgcacc     2940

gtattgattc atgctatagt tacttaatca aagatttttt tcaaacctgc cttacatata     3000

ggcccacttt aaaagcacct gactagcatg tgttcttgat tgcaaaattg gcagaggcag     3060

ggtgtcaact tgattaggtg tttttatggg aatgtaattt gaaatcacta cttcagaaat     3120

ttgacttaaa attcttgagc acgttaatat gtttttaaga tctgattatc tttgagagat     3180

cttctgttaa tacacattgg ttgttaaaga gtacccaaat tctaggacaa tgcttaaagt     3240

gttaaaatac cctagatact gtgttatgtg caactgtaga aaccctccag aaatttccac     3300

tgctgttctt cactttcatc ttgtctgcta tcaaaccact tctgacaaaa ttagctgttt     3360

tgaattaccc atatcactgc cagttttatt ttaaaatatt ttgtgtttga agtatctgtg     3420

catgggatcg ttgatgttta tcagaactgt tcactttcag aaatgatttt ttaaagcatt     3480

ttgttgaaaa tgcggttgct tttttaacat tattttagag ttgtatcaaa attttcctgt     3540

tttctgtata ttgttgtgtc atttcttggc tttttaatat tttgactaca atgccctaat     3600

gcgaagaagt atggacatat aaatattaca agagaaatta gttaatagta aagggttaaa     3660

aggtaagtaa aatgtccatg aaaataaaat tttctttgaa cagtttaaaa atggaatcac     3720

aaaaatctaa ctgcacttga aatgaaactg gaaattttat actaattaaa tcctttattt     3780

accttttcat attttatcaa tggaaccttt taattgctcc ttctatatca ctcttctcct     3840

tgcttggctg atctcattac atgactttcg ttacagacag tgtgagtgta ctagatttgt     3900

ttgctgctaa tccgttattt taagtgttgt cagaaggaaa taacttcttg gtttgaccaa     3960

gtaattttgc aaagtccttc tctacctgat aacacgtgaa tgtatagcag taaaggtgaa     4020

aattgcaggc cttgttttgt tcttcatacc cccttcagtt gtttatgggt taatgttatt     4080

tgaaaactct tccttttttt aatgtgtaaa aacaatccaa agagataaat ccttgcatag     4140

acaccaaaaa cagtgtctca gagacctttt cattttttcc ttagttaata actgtagtgg     4200

atgtgaaaac aaacgagttg aattttaaaa catagcattt attagtgcta tacagtcaca     4260

ttcctttcag ccagtagtaa agttaaacag atgagtgata cagtacctga atggtactgc     4320

ttctgaggca acactttgga ttgaaagtgc tgcttttggt taaaggaact atgttgtgga     4380

aagcatattc cagtgtaaat ttgcagatgt gtgttttttt tttttgtcac ttttcataag     4440

gtttggagta agttgcagtg gcttttgatc atagtttagc ccatttaatg gtccttttac     4500

ctagaatgtt cttaagcagt taatgacaat ttggaataca cagataactt gtagcttaag     4560

atactatttt catttaattc tcctgtggag aatattgctt tattttttac tagtttcagg     4620

tcagttatta aaataaacat ggaggtttta atgaatgttg tataatattt tatagtgaag     4680

gaaaattgtg gaaagggcaa agactttctc tttcccttat gtatttaact gtgccaatct     4740

aaatacatac tgttttatac aatgagatgc attacaagac ttttctgttg gagtgctctc     4800

gacattttgg ttttcatacc tgaatgatca ttgcattttc tgtattttct aaaatggctc     4860

caattttgtg ttttaagctt cagcttaaga ggaagtttat gttctaattc ttgactgaga     4920

atacagtatt gagattctct gttttacaga taacaactgg tttttattac tcattaagtt     4980

catttgcatc ccgtagccct ctgtaaatgt ttcccctagt tgtatgtacg taaatgcacg     5040

cttatccagt gtatattaga catttttgtg ctaaaatata ttaagtggga tttttgtagc     5100

aaagcattct atttttctgt tcttacagtg tgtgtgtgtg tgtgtgtgtg tgtgtatgcg     5160

tttttttaac cttaacttca gtttaaacac tggtgtattt atttttttaa gcaacttgac     5220

tcttagaagc cttagactga ttttttcaat aaatattcaa ccaaaaatta taaatttatt     5280

aagatgtggc cttacatatg gcattccttg tgttcgtaat gtgagatttt tgatttagat     5340

aaatcaagat tcaggattaa agtttcattg taagttgaaa tagaaaatgt attaaaatgt     5400

ctaggcttct gggaggaagt tcttatactc ttctttcttg gcattagaaa gaagcaatat     5460

gaatttttgt gaatattcta aatattcagg caacactgtt cagattgatt taggtttgtc     5520

ttaaccaatg ttcttttttt agaatttcag gttgtggcat tcactgagta tgcagctact     5580

atggtttttg tatgggacgt ataaatactt gattatatac gacagatttt aatgtcttta     5640

aagacttcct gctgtattaa catattgtaa tggagtcttt taaatactag gttgaattta     5700

attgaagtca cacacatctt gaagtggtaa ctgcatagta aatactacca agagtttttt     5760

tcacgtggga gtatcctaaa actctgccat gggtgtaaat gttttacatt aatttcataa     5820

ttggacagac cctgcattta gcgaaaacat tttgttttga aagtgtgttc tttttgtcgc     5880

actgttactg cgtaacactt ctcaacattc tgtaagttaa attattttaa aataactatg     5940

gtgaattcat gtttattttt ttactttgaa aattgtagta ctcaggtggt atttaatggg     6000

aaaggatcct ttgggtataa atcataatgt attttaagga atgcatctat aacattgata     6060

actttagcct taaaaaaaag gtctattatt ccttcctctg catcccatgg tatattagca     6120

aagtagttta cagccctgta cagccttaca aagttgtttt acaattttta atggaaagcc     6180

cttaacaaca acaacaaaaa attgtatcat tttaccaata tccacgaatt actgatcaca     6240

gtttgtaaat aatttgttta atatcagaag gccaaagaaa gtcttaaaat tttagctatt     6300

gactctatgg tgacttcaca ataagatttc tgtgcaaaaa ggtaaggtga taattgatct     6360

aatagacttt tttttttttt tttttgctgt ccatgagaat tagacttcat attagcttca     6420

attaaaaagc tcattccatt ttattaaaat gtttgtaatt gcaattttgt gtttaatgtt     6480

tactttgtct ttcctttctt tagcatttag gtgactgttc ggcagtttga tatatggcca     6540

ttgtcggcct taaactgcac tagtaacaag catggtattt atcttgtatt gaaaataaaa     6600

caaacttttg ataagaaaaa aaaaaaaaaa                                      6630


<210>  403
<211>  6630
<212>  DNA
<213>  homo sapiens

<400>  403
ctcggaagtg acgcaagcgc ccccccaccg ccgctagatc cgctgctgct gccgcggcgg       60

gcagacctgc aggaggcggc ggcggcggcg gcggccgagg ctgaaggaag atggcggacg      120

gcgtggacca catagacatt tacgcggatg tcggcgaaga gttcaaccag gaagctgaat      180

atggtgggca tgatcagata gatttgtatg acgatgtcat atctccatct gcaaataatg      240

gagatgcccc agaagaccga gattacatgg atactctccc accaactgtt ggtgatgatg      300

tgggtaaagg agcagcacca aatgttgtct atacatatac tggaaagaga attgcattat      360

atattggaaa tctaacatgg tggacaacag atgaagactt aactgaagca gttcattctt      420

tgggagtaaa tgatattttg gagataaaat tttttgaaaa tcgggcaaat ggccagtcaa      480

aggggtttgc ccttgttggt gttggatctg aagcatcttc aaaaaagtta atggatctgt      540

tacctaaaag agaacttcat ggtcagaatc ctgttgtaac tccatgcaat aaacagttcc      600

tgagtcaatt tgaaatgcag tccaggaaaa ctacacaatc aggacaaatg tctggggaag      660

gtaaagctgg tcctccagga ggcagttccc gtgcagcatt tccacaaggt ggtagaggac      720

ggggccgttt tccaggggct gttcctggtg gggacagatt tcctgggcca gcaggaccag      780

gagggccacc cccacctttt ccagctggac agactccacc acgtccaccc ttaggtcctc      840

caggcccacc tggtccacca ggtcctccac ctcctggtca ggttctgcct cctcctctag      900

ctgggcctcc taatcgagga gatcgccctc caccaccagt tctttttcct ggacaacctt      960

ttgggcagcc tccattgggt ccacttcctc ctggccctcc acctccagtt ccaggctacg     1020

gcccccctcc tggcccacca cctccacaac agggaccacc tccacctcca ggcccctttc     1080

cacctcgtcc acccggtcca cttgggccac cccttacact agctcctcct ccgcatcttc     1140

ctggaccacc tccaggtgcc ccaccgccag ctccgcatgt gaacccagct ttctttcctc     1200

caccaactaa cagtggcatg cctacatcag atagccgagg tccaccacca acagatccat     1260

atgggcgacc tccaccatat gataggggtg actatggccc ccctggaagg gaaatggata     1320

ctgcaagaac gccattgagt gaagctgaat ttgaagaaat catgaataga aatagggcaa     1380

tctcaagcag tgctatttcg agagctgtgt ctgatgccag tgctggtgat tatgggagtg     1440

ctattgagac actggtaact gcaatttctt taattaaaca atccaaagta tctgctgatg     1500

atcgttgcaa agttcttatt agttctttgc aagattgcct tcatggaatt gagtccaagt     1560

cttatggttc tggatcaaga cgtgaacgat caagagagag ggaccatagt agatcacgag     1620

aaaagagtcg acgtcataaa tcccgtagta gagaccgtca tgacgattat tacagagaga     1680

gaagcagaga acgagagagg caccgggatc gtgaccgaga ccgtgaccga gagcgtgacc     1740

gagagcgcga atatcgtcat cgttagaagc tgaaggaaga ggatcacctt ccaagacaaa     1800

acagtcttca tgggggaaaa atgacgcttg tccagcagtt tgcttcttgt gattgaactg     1860

aacctgtaag gattcatgga taaaatgaac aggaatagat ctgaataaag caaatctgca     1920

taaatggtaa ccagtagctc tacttttatt ttttatgttg cttaactgtt ttatttgaag     1980

gaaacctgtg tgatttaaaa agttatagct tttgcaactt tattactggt tatatacatt     2040

tggccattat gatgtgcaag caattggaaa aaaagtcaag taaatgcttg tttttgtagt     2100

agtttgttct tgttaaaaat gtttatatga taatgtctgt aaacagcatc actttgatta     2160

caatagatgt agtgttgtaa taaactgttt aatggggctg atgtgtaaag ctgttcaagt     2220

tatttgatgt ttacacctca gggaaagtct tgtgttcagc aatatctaaa gataatgtta     2280

ctatgacaac atttttactg tcctttaaag cattgcaata gcgtttttgg atatgcctca     2340

atctaatctt gcgttcagtg aattaaacat agtaattaag tgtcttttgc ccttgatttt     2400

gatattagaa taggtgatta catggatatt taatatttct atattctgct tttctagctg     2460

tttttaccta gttagcttgt gactttgctg aatggtatgt aaacttgtaa aaatagagat     2520

ttgacagaca tagcaatcta gtcaatgtgt aaggggtcaa aaaaacagag gttttaacac     2580

ataagtaaaa acccgtacat atttgatgtg taatgcaggt taattacaac acagatgtac     2640

cgaaacactt aattgtgaac cgctaacatt gaagaaattt tgacaattcc gatttgatgc     2700

tgcaattact tgctgttttt attgatctta tggtttattt cttaagccat agtcagtgta     2760

aatacagccc tgcagcaggt aaatgtgagt aaagagagcc ttatattttc caattggtat     2820

aaatttttga aggatgtgat gttcattaac attcggttgt attccccagt atttgtaatg     2880

ggaaattaca gataaaccgt gtctgcacag tttaaggaat actatgtata ttcatgcacc     2940

gtattgattc atgctatagt tacttaatca aagatttttt tcaaacctgc cttacatata     3000

ggcccacttt aaaagcacct gactagcatg tgttcttgat tgcaaaattg gcagaggcag     3060

ggtgtcaact tgattaggtg tttttatggg aatgtaattt gaaatcacta cttcagaaat     3120

ttgacttaaa attcttgagc acgttaatat gtttttaaga tctgattatc tttgagagat     3180

cttctgttaa tacacattgg ttgttaaaga gtacccaaat tctaggacaa tgcttaaagt     3240

gttaaaatac cctagatact gtgttatgtg caactgtaga aaccctccag aaatttccac     3300

tgctgttctt cactttcatc ttgtctgcta tcaaaccact tctgacaaaa ttagctgttt     3360

tgaattaccc atatcactgc cagttttatt ttaaaatatt ttgtgtttga agtatctgtg     3420

catgggatcg ttgatgttta tcagaactgt tcactttcag aaatgatttt ttaaagcatt     3480

ttgttgaaaa tgcggttgct tttttaacat tattttagag ttgtatcaaa attttcctgt     3540

tttctgtata ttgttgtgtc atttcttggc tttttaatat tttgactaca atgccctaat     3600

gcgaagaagt atggacatat aaatattaca agagaaatta gttaatagta aagggttaaa     3660

aggtaagtaa aatgtccatg aaaataaaat tttctttgaa cagtttaaaa atggaatcac     3720

aaaaatctaa ctgcacttga aatgaaactg gaaattttat actaattaaa tcctttattt     3780

accttttcat attttatcaa tggaaccttt taattgctcc ttctatatca ctcttctcct     3840

tgcttggctg atctcattac atgactttcg ttacagacag tgtgagtgta ctagatttgt     3900

ttgctgctaa tccgttattt taagtgttgt cagaaggaaa taacttcttg gtttgaccaa     3960

gtaattttgc aaagtccttc tctacctgat aacacgtgaa tgtatagcag taaaggtgaa     4020

aattgcaggc cttgttttgt tcttcatacc cccttcagtt gtttatgggt taatgttatt     4080

tgaaaactct tccttttttt aatgtgtaaa aacaatccaa agagataaat ccttgcatag     4140

acaccaaaaa cagtgtctca gagacctttt cattttttcc ttagttaata actgtagtgg     4200

atgtgaaaac aaacgagttg aattttaaaa catagcattt attagtgcta tacagtcaca     4260

ttcctttcag ccagtagtaa agttaaacag atgagtgata cagtacctga atggtactgc     4320

ttctgaggca acactttgga ttgaaagtgc tgcttttggt taaaggaact atgttgtgga     4380

aagcatattc cagtgtaaat ttgcagatgt gtgttttttt tttttgtcac ttttcataag     4440

gtttggagta agttgcagtg gcttttgatc atagtttagc ccatttaatg gtccttttac     4500

ctagaatgtt cttaagcagt taatgacaat ttggaataca cagataactt gtagcttaag     4560

atactatttt catttaattc tcctgtggag aatattgctt tattttttac tagtttcagg     4620

tcagttatta aaataaacat ggaggtttta atgaatgttg tataatattt tatagtgaag     4680

gaaaattgtg gaaagggcaa agactttctc tttcccttat gtatttaact gtgccaatct     4740

aaatacatac tgttttatac aatgagatgc attacaagac ttttctgttg gagtgctctc     4800

gacattttgg ttttcatacc tgaatgatca ttgcattttc tgtattttct aaaatggctc     4860

caattttgtg ttttaagctt cagcttaaga ggaagtttat gttctaattc ttgactgaga     4920

atacagtatt gagattctct gttttacaga taacaactgg tttttattac tcattaagtt     4980

catttgcatc ccgtagccct ctgtaaatgt ttcccctagt tgtatgtacg taaatgcacg     5040

cttatccagt gtatattaga catttttgtg ctaaaatata ttaagtggga tttttgtagc     5100

aaagcattct atttttctgt tcttacagtg tgtgtgtgtg tgtgtgtgtg tgtgtatgcg     5160

tttttttaac cttaacttca gtttaaacac tggtgtattt atttttttaa gcaacttgac     5220

tcttagaagc cttagactga ttttttcaat aaatattcaa ccaaaaatta taaatttatt     5280

aagatgtggc cttacatatg gcattccttg tgttcgtaat gtgagatttt tgatttagat     5340

aaatcaagat tcaggattaa agtttcattg taagttgaaa tagaaaatgt attaaaatgt     5400

ctaggcttct gggaggaagt tcttatactc ttctttcttg gcattagaaa gaagcaatat     5460

gaatttttgt gaatattcta aatattcagg caacactgtt cagattgatt taggtttgtc     5520

ttaaccaatg ttcttttttt agaatttcag gttgtggcat tcactgagta tgcagctact     5580

atggtttttg tatgggacgt ataaatactt gattatatac gacagatttt aatgtcttta     5640

aagacttcct gctgtattaa catattgtaa tggagtcttt taaatactag gttgaattta     5700

attgaagtca cacacatctt gaagtggtaa ctgcatagta aatactacca agagtttttt     5760

tcacgtggga gtatcctaaa actctgccat gggtgtaaat gttttacatt aatttcataa     5820

ttggacagac cctgcattta gcgaaaacat tttgttttga aagtgtgttc tttttgtcgc     5880

actgttactg cgtaacactt ctcaacattc tgtaagttaa attattttaa aataactatg     5940

gtgaattcat gtttattttt ttactttgaa aattgtagta ctcaggtggt atttaatggg     6000

aaaggatcct ttgggtataa atcataatgt attttaagga atgcatctat aacattgata     6060

actttagcct taaaaaaaag gtctattatt ccttcctctg catcccatgg tatattagca     6120

aagtagttta cagccctgta cagccttaca aagttgtttt acaattttta atggaaagcc     6180

cttaacaaca acaacaaaaa attgtatcat tttaccaata tccacgaatt actgatcaca     6240

gtttgtaaat aatttgttta atatcagaag gccaaagaaa gtcttaaaat tttagctatt     6300

gactctatgg tgacttcaca ataagatttc tgtgcaaaaa ggtaaggtga taattgatct     6360

aatagacttt tttttttttt tttttgctgt ccatgagaat tagacttcat attagcttca     6420

attaaaaagc tcattccatt ttattaaaat gtttgtaatt gcaattttgt gtttaatgtt     6480

tactttgtct ttcctttctt tagcatttag gtgactgttc ggcagtttga tatatggcca     6540

ttgtcggcct taaactgcac tagtaacaag catggtattt atcttgtatt gaaaataaaa     6600

caaacttttg ataagaaaaa aaaaaaaaaa                                      6630


<210>  404
<211>  10998
<212>  DNA
<213>  homo sapiens

<400>  404
gattcacagg gcctctgagc attatccccc atactcctcc ccatcattct ccacccagct       60

gttggagcca tctgtctgat caccttggac tccatagtac actggggcaa agcacagccc      120

cagtttctgg aggcagatgg gtaaccagga aaaggcatga atgagggggc cccaggagac      180

agtgacttag agactgaggc aagagtgccg tggtcaatca tgggtcattg tcttcgaact      240

ggacaggcca gaatgtctgc cacacccaca cctgcaggtg aaggagccag aagggatgaa      300

ctttttggga ttctccaaat actccatcag tgtatcctgt cttcaggtga tgcttttgtt      360

cttactggcg tctgttgttc ctggaggcag aatggcaagc caccatattc acaaaaggaa      420

gataaggaag tacaaactgg atacatgaat gctcaaattg aaattattcc atgcaagatc      480

tgtggagaca aatcatcagg aatccattat ggtgtcatta catgtgaagg ctgcaagggc      540

tttttcagga gaagtcagca aagcaatgcc acctactcct gtcctcgtca gaagaactgt      600

ttgattgatc gaaccagtag aaaccgctgc caacactgtc gattacagaa atgccttgcc      660

gtagggatgt ctcgagatgc tgtaaaattt ggccgaatgt caaaaaagca gagagacagc      720

ttgtatgcag aagtacagaa acaccggatg cagcagcagc agcgcgacca ccagcagcag      780

cctggagagg ctgagccgct gacgcccacc tacaacatct cggccaacgg gctgacggaa      840

cttcacgacg acctcagtaa ctacattgac gggcacaccc ctgaggggag taaggcagac      900

tccgccgtca gcagcttcta cctggacata cagccttccc cagaccagtc aggtcttgat      960

atcaatggaa tcaaaccaga accaatatgt gactacacac cagcatcagg cttctttccc     1020

tactgttcgt tcaccaacgg cgagacttcc ccaactgtgt ccatggcaga attagaacac     1080

cttgcacaga atatatctaa atcgcatctg gaaacctgcc aatacttgag agaagagctc     1140

cagcagataa cgtggcagac ctttttacag gaagaaattg agaactatca aaacaagcag     1200

cgggaggtga tgtggcaatt gtgtgccatc aaaattacag aagctataca gtatgtggtg     1260

gagtttgcca aacgcattga tggatttatg gaactgtgtc aaaatgatca aattgtgctt     1320

ctaaaagcag gttctctaga ggtggtgttt atcagaatgt gccgtgcctt tgactctcag     1380

aacaacaccg tgtactttga tgggaagtat gccagccccg acgtcttcaa atccttaggt     1440

tgtgaagact ttattagctt tgtgtttgaa tttggaaaga gtttatgttc tatgcacctg     1500

actgaagatg aaattgcatt attttctgca tttgtactga tgtcagcaga tcgctcatgg     1560

ctgcaagaaa aggtaaaaat tgaaaaactg caacagaaaa ttcagctagc tcttcaacac     1620

gtcctacaga agaatcaccg agaagatgga atactaacaa agttaatatg caaggtgtct     1680

acattaagag ccttatgtgg acgacataca gaaaagctaa tggcatttaa agcaatatac     1740

ccagacattg tgcgacttca ttttcctcca ttatacaagg agttgttcac ttcagaattt     1800

gagccagcaa tgcaaattga tgggtaaatg ttatcaccta agcacttcta gaatgtctga     1860

agtacaaaca tgaaaaacaa acaaaaaaat taaccgagac actttatatg gccctgcaca     1920

gacctggagc gccacacact gcacatcttt tggtgatcgg ggtcaggcaa aggaggggaa     1980

acaatgaaaa caaataaaag ttgaacttgt ttttctcatg catatgattt ccattatgcc     2040

tacagatatg gacccttttt ctgtcttgac ttcttgatca ttgacctctg tttacaacag     2100

gaggagggta ctaaagtcgg aggatttcct tttcttgtag ctcactgccc acagactttc     2160

tacagagtca ccaatctgtc agtaacaaca gagagtccag caataatcgg tgactggtgt     2220

gcatagcgga ggttgcggca ttactttgca caactagctc tttgtttcat gaaggaagtt     2280

tttatttttt caccgattat tgccagtccg caggatggca tgaaaagggt ccatagcagt     2340

agcaacaata gcattataat atattacagg gtaaatgggc atgaagacta tatatagcta     2400

aaagagatat tgtttatata ttgttttaag taatataaaa tgtagttact ggtgtagctt     2460

ttcctgttga attgataagg cactttcatt ttgcaccttt ttctttaaat taaatgctag     2520

cgtgttcact gtcgtgtcgc atgtgcacca gaaacacaag tttaactgag aaggcttgga     2580

aggtacgttg ggaggtattt atgctgctgt ttacaaaatt atttttaaga gactggctgg     2640

tcatatctag aaatcaccac gttggatttt ttttttaaca tgtgaatttg gaattagaaa     2700

cggaactctc cctaaattat actttgcttt ttggtaagtt taatgataga tgtgtttatg     2760

cttcatacaa agttgaatga ttgattggcg tggtggacat ataccatcat gctcattttt     2820

tttttttaaa gctttttaaa atgccacctc atggaggcga gggggaggag aagctcattt     2880

tacacaattc agtagttaaa tatggactcg gtctcaactt ggaattctta tgctttgaga     2940

acaaatcaac aaccagaata tttattggaa tctagctttt attataagaa ggacccaaag     3000

attatatcct gagcaaatgc acactcccca tgtgaggaca tgaagtattt actttgtgaa     3060

tgtttatgtt cttggtataa tctaggaacc ctatgagttt atctcagagt gaactaattc     3120

tagatttgtt gtcaatagat gctataattc aagaatgttg ctctccatat ttgaaaaacg     3180

atggatagga gggtgaggga agcatacaat gttgaaccag tttctcttat ttaaatatta     3240

aatactttaa gcctttaaag tgaagttgat gctagctgca aacatttact cttgtattta     3300

tcttcactag gaaactgtgg actgtaattt attttattaa atatttagaa gattatttgg     3360

cttgtgtgtt caggtgagaa atactgagtt gtttttgttt aatttcatgg tttttttttt     3420

tttaatgatc cctagtgggg gaaggggaaa ggaatagtct gataaacaga tgtgcatatt     3480

ttaaaaacaa gtgacctttt gggaatgtag gcatttagac gatgatttta gtcgcactag     3540

gggtgggatt caaactactg gtcaaagacc attttgtaca gaaaagggaa catctccgat     3600

gggtgttaag gtaggagttt ccatgcagcc ctttatgtct gagaaatagt ctcctctgcc     3660

attggggtcc ctgcggaatc ttctacagga attgcagctc ttcacgtcat gctaggttac     3720

cagcatgggc ttcccagagc acttcactct gtttctaact ccactgactt ttctgacttg     3780

tttcttgagg gacttggaaa aggggaaggt attattcaca cagatgtgtg tatgaagcct     3840

aaataacatc caactttttt tccaaaaaca tagtaagagt ttaaccataa atagaagagt     3900

aatattcctt taaatttctt acaggcatgt aaaattttat gtgtttatag agagatgcta     3960

actgtcagca tatagtattt atattggggc aagaagggtt aaatcaaatc tttaatttaa     4020

gtaagcatag ttcctttaaa gatcagtagt atttatactc tgaaaagagt accaagctta     4080

gttcagttat ttattcatcc attttttttc tattgtttct cctctggggg gaaatggtgt     4140

tttgtttttg tttgagtttt gtgttttagt tttttggttt tggttttgtt ttgttttttt     4200

gtcattcaga ttcactaaat ttggggatgg ttttattaaa gtatattaac ttctttttaa     4260

ccaaagcttt ctgaatatga ccagcctcag gtgctagcgc attaaagagc aactaaacct     4320

aattccagtg tcgatttgtg aaataataaa agctaattga atttctctaa gggtgagaga     4380

gaacataatg atgaacttaa aaagaaattc cttttcccag aagggattct gcatgtacct     4440

acaaacaatc atgctctaac cacagtaata gtcatgccat ggtgacattg cttttacggt     4500

aaaccaagat aggtaatatg atgcttcttc ccaggtgttt ctgaaagaaa agcagcggtg     4560

gagcttaaga gccaagtcca ctgattgaca taataggatg gaattgtaga cagagacatg     4620

ctccatgaaa caaggaaaca actgactact atttggatct aagttgggat ctgatgttaa     4680

acaataaatt cagtttaaaa aaaatatgga gctcagaaaa ggatgtgaaa aactttgcat     4740

tttcctttct tcattattac aaaaacacct atgtgatgac ataaaatact tgggtgatat     4800

cagaacaatt atccttaata gtttttataa ttaaagtttc ctaaacttca gtctccaata     4860

gtcttttaag gattggaacc acatcactgt cagccccgct gctacaatgc ctttgtacaa     4920

tttttttaca taaggcaaat aaggcttttg tacaaagcct gaataccttc tgttccaatg     4980

gtgtccaaat ggttattata ttgtgaaaaa cctggccttg gtcacaatgc aaacaaaagt     5040

acagatgaaa gtgctttttg gacagtttgc aaattgtgtt aaagctacgg atttttttta     5100

aagtgttcag catcttaacg tgtattaaag ctatggattt ttttttaaag tcttcagcat     5160

cctaattcac cctttctaac ttaagaaaaa catgacttaa gacactgctt ctaagtttgg     5220

ttgttcttta tagtgtggat acccagttat ctgtgagcgt atgggggtgg gctgagggtc     5280

aggtgaggaa ggagtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgatttgcat     5340

gtgtatgatg tgtgtgcgtc ggaccgcttc taggctacta agtgtcaatg gaaaagaaaa     5400

tgtattcaaa atacttaaat caaaactaga agatggggaa aaaaagattt attctataca     5460

aagccttgtc tggaccactt tagagagact tctatttttt taacccttct ataaatattt     5520

gatggcactt gaaatattcc tgcaataaaa tgtgatttgt gtaaagaaaa aaagattttg     5580

taatgtgaaa caaagaaaga aagtaatgta attttctaaa aaaaaaaata caaacaaaca     5640

aactttgtat tattttcttg atggaatttg tctatctgtc tttggaaaac tttttatttc     5700

attgaatgtg ccatagtaga aatgtgtgtt tttagtttta gactaaggaa tagctagttg     5760

ttgtgttccg acattccaaa atgcaaaaca acctagtagt atctttcatg aaaaggttta     5820

agtagtatgt aagcttctct cattgttgct tttttgcaca tgttcttcat tcctctctag     5880

tgcaatatgt acatagagca cttgcgggtg taccttgatc cctcagggaa aaatacatat     5940

ttgtacagtt ttttggggtt tttttgtttt ttggtttttt ttgttttgcc ttttgttttt     6000

ggctaaggaa tgtcgatcga atcacttgtt attgttgagg ggcagccaga taataatcct     6060

aaagccactg tttccaacat tgattgttta aatcatatgt ccttccaatg ctattatttt     6120

aagataataa taaaaagtta ttttctgaca gttctttgtg ctgactggtg aaaaacaagg     6180

gtaaataagc accttataat tgacttactg tgaatgacaa tccatcttgg tatcaacgat     6240

agaagcccta tcattttgga gttggggtta agagtcagaa acaatgtgct cagggatctc     6300

ctaaaactct taaaacaggg tggccagtac tactgggaca aattgtgttt tttattatta     6360

ataataatga taataatact atccctccaa ggcacaagtg aactatatag aactgcgtgt     6420

gtgtaaactc tttactctcg tctcattttg ttgagtttag aacttgatgt gctcgtcagt     6480

cttgtgtttc aaaacactga ataacttcca aagcaaagtt atgccagtgt gttcaaaaga     6540

taaattaata atgtaccagc aaagagcatc attcaaagta tagtccttgc atattccagt     6600

taccatttct ctaataatta aaatattcat gataaatata tatatagcat catatgttaa     6660

aaactatttc aaattctaca tattaaggat gaaaatttta aaatccagta ataagaggag     6720

agacctgcct atcagtacag tgatataggt aaaagatgaa atatgttttt aaaataccag     6780

caattaacta ttgttttcat gggttctcct ctagaagcaa accaaaaatt ccttcatgga     6840

aaacaattct tacttctaca tgtgtagttt atatctgatg cattacaaga gctaatgttt     6900

aaagacaaaa caaaacctgc ctgtatgaca gcagcaactc gagccaacat ttagtgttac     6960

atgttatatt tttgaaatac cgttttgtta tcatattcca catattactt tccataaagt     7020

cagagaagtt caatgtaatt gttggctctg attcttccac cttgggatac acattcacaa     7080

gaagatttat atattttctt actatgatag aggaacataa tctgggaaaa cttcccatgt     7140

ctgtaagatg aaaaggatac ctttaccatg ttgtttttga taataaagaa tatggaaaat     7200

ggtagaaatc tctcctctct atgtgtattt gtatatgtgt gtatacacac acacgttgac     7260

atttttacat aacatgtgat tgccacttct tataaagtta tgatatagaa ccccatgaaa     7320

acaactttat attatagatc aaataatgtg cccagaaacg caattgcaac agtaaatctt     7380

gatctattgg taagagtcta tgatacaggt cttcattcta tccctaaaca taatgttagt     7440

aaagaggttc catcagattg tattatagag accttcctat tgctatttat ttttaagaga     7500

tgagaagact gactagcaat gtctccacag tgcaattggt ttcacttctg ggtctgtctg     7560

tctgtttgtg taggtgagat cagtgttgtc aggctctcag aataattttt aaaagaatcc     7620

agaagcctga cttcacacca agtagccatc ctagatgggc gggggggatc tccatgttca     7680

accaaaccct cagaacttag agcaataaat acattcagtc atttatttat aaatgaatga     7740

cagaatattc aatccaaata gaaacaacct tttgtcagtg atgcaacata acatggagtc     7800

ttatattgag aaagtgaata tgaatatttt aaatagatgc ctaggaaatc tgtgtttgct     7860

gtttacattt aatgtacttt gccacattag cagtaccaca cttcttttac tttcatcctt     7920

ctaagaacta atgaaagata gcttgctatt agctttgaca tgttgcacat gccattatgt     7980

tgttctctaa gaacaactaa attctctcca gtgttcatgt gtgattcctt tttcatcatt     8040

attactttaa tgtggatgaa tactatttct aggaacttga ttatcactga acagattgca     8100

tatgtaaatg cagataattc ttgagcaata tagtgaaaat gatttcacaa aaaaaatcca     8160

tatgtactgt atacatcttc ctgaatccaa aattctcctg ttatccacac agtttgaaat     8220

ctcatattaa acagtggtaa atttttaaac attaggacat tagctggctg cttctataaa     8280

tgtacctgta ttgtctgcct gctccttttg tggagatgtg tttttgtatt ggatgtttgg     8340

gccaatggga ggcttcaagc tacaacatat tttcccactt taaataatat ttaacatatg     8400

acaaacccca gacaaggctt ttaatatgta taaagaactg cagtgttagg tggtttattt     8460

gcaaactgtt ttcagtgttg tccattttta tggcaccttt aacaatattc ttgtttccaa     8520

agtacaaaaa aaataggtta aataatctag ccataactga atgtcaagca ataaaacaaa     8580

tgacttttgt gcatagactt aaaaaataca aattttagac atctgcatgt aaatgcaatc     8640

tcttgtttac tgctttcttc aacttgagca atcgattcct tatttactat taacttaaga     8700

acttgtaacg gcctgtaaac attttctctc ttactcttct ttcaaattta cctgtccctg     8760

cttttgagtc ataatattta atgttgttct gcacatctct atacagttaa ctttttggct     8820

ttcattctgt atagataaga aaatgttata ttataaacag cctactcagt gcaaatattt     8880

atctgtttat caaatccaca atatgctgta taataccggt tttactatat aatctatttt     8940

agacatagct gtttagaact agagtgtgct atttttgtgt ttttctgatg tgtggtgcta     9000

gacaagttac ttttgtgaac aacaaaaatt atccctttta ttcctagaca ataccacctt     9060

tgggtcttgt taatttcact gagtataact atatatttgt atatatatac atatatatat     9120

atatctacct atgcccaact ggcagctgta tcagagtgct ggatttggga catgcttttc     9180

tctttaaata cataatatca ttatataaat tattctagag tgtatttaat taggataaaa     9240

ttacttcctt agtatggata tttgacatct atagggtgaa tttgtttata aatatggcta     9300

tatggaaact tattagcatt tactttatgt ttgctacttg gctttacagc atatctccta     9360

agctgaaaaa taatttgcca ggccttcaag atcctaaaga aacttgttta atggagtaat     9420

atactttttt ttcttattaa ggaattgtat tactggcacc taacacagtt gtattcttag     9480

ctcctattat agataatggg catttacata aaatatccta gatggcttga tggcagaata     9540

aacctttccc ctcctacctg agtcatgaga aggatggaga cgtcctctgc cataacatgg     9600

gccataaagc aaattcgaca tgggatgttc tgtttcagta tgacctcaac cagttccatg     9660

aactgagtga aggaccttca ttttcaaagt tatttaataa gtagcttaat taagcctttc     9720

tacccattct cccaagatct actggcatta ttgaaaagca aagtttatca aatatctaac     9780

taaggatgta gttaacctta ttaaatattg attagaattg ttctgtaata ttactgaatt     9840

tgtaagatct ttagcaaaga tttttgagca atttataaat gtagagcaaa tgtttctgtt     9900

tactgcactt tttgtaactg aaggtgataa attctcaagc catgattatt ggcttccatg     9960

cactgcaata tttatccaca attctagaca ttttccattt ttgtggaaga gttgctgtta    10020

ccttaattat aaatgcaatt gtgtggttaa tgagagctaa tgctagtagt taacctttta    10080

aagtggattg gctacagttg agggagaaat ctcttttaat ataaatcaca tcattcctta    10140

actgcctctc ttggaaagag attgaaacct tttttttaaa gcacgattta gcatcctaag    10200

cttcctgagg gtagagattg tatctttttg cgtctgcaca atggctagca catgtcagca    10260

tttgacaatt gttaaatgat aacaagtgtg ccccaattaa aacgtttttc ctgggttgtt    10320

ttgttaaatt tacaaagtaa gccaagcctt acggttaaca ttctcctcta caaccaagta    10380

ttaaagccac atttaaaaag accacatgaa atgctgattc taattgtgtg taggtcttga    10440

ggattaagca cacaaatttc acaaacttct gtttgagtaa acaaactcag ccttctgtaa    10500

atatacatgc aagtttggaa acagtaatac tgtacctata aatatatgct gtctgttttg    10560

tgtacagtat gtaaaaactc cttttctgcc acactaaaaa tgcaagccat ttatgggaat    10620

cctaaaacta gtattgaact aaaactttgc taatgatctt tattagagga tcgtccaact    10680

tttcacttac cttgggtttt cttttcaatt cactcttaca ctagtctgct tatttccagc    10740

tgtttatttt attgagtcct gaatttaaaa aaaaaatatt ttgattcatt ttgtaaatac    10800

aagctgtaca aaaaagagag atttaatgtt gtcttttaaa tactccaatt ttcattctaa    10860

tatgaatgtt gttatattgt acttagaaac tgtaccttta atattacatt acctttatta    10920

aaagtgcatt gaacacatca attttagatg tgctttatgt actgttatcc tataataaaa    10980

cttcagcttc taatggaa                                                  10998


<210>  405
<211>  8051
<212>  DNA
<213>  homo sapiens

<400>  405
gtctctccaa gggaatgaaa ggtgagggga gcgtgagtgc aggcatgatg ggaatctccg       60

tgacttgtga accaaggact gggttttgct ctggaagcct gtcctgattg cttctgtaat      120

ctggcgctat gcatccggat cttggaccct tatgtacact gctgtatgtt actcttacaa      180

ttctgtgctc ttctgtgagt tcagacttgg caccttattt tacttctgag ccgctctctg      240

ctgtccagaa acttggtgga cctgtagtac tgcattgttc tgctcaacct gtgaccactc      300

gtatctcatg gctgcataac ggaaaaacat tggatggaaa cctggaacat gttaagattc      360

atcaggggac tctgacaatt ctttctctca actcctctct tttgggttac taccagtgcc      420

ttgccaacaa tagcatcggt gccattgtga gtggccctgc gacagtatct gtggcagttc      480

ttggtgattt tggttcatcc acaaagcatg ttattacagc agaagaaaaa agtgctggtt      540

tcattggctg cagggtaccg gagagtaacc ccaaagctga ggtgcgctat aaaatccggg      600

gaaaatggct ggaacattcc acagagaatt acttaatcct tccatcagga aatcttcaga      660

ttttgaatgt atccttagag gacaagggat catacaaatg tgcagcttat aatcctgtca      720

cacatcaatt aaaagttgaa cctattggcc gaaagctcct tgtgagtcgt ccttcttcag      780

atgatgttca cattcttcac cccacccatt cacaggcatt agctgttctt tctcgtagcc      840

ctgtaacctt ggagtgtgtg gtgagtgggg tcccggctcc tcaagtgtat tggctaaagg      900

acgggcagga cattgcacca ggaagcaact ggagaaggtt gtattctcat cttgccactg      960

atagcgttga cccggcggac tccggaaact attcctgcat ggcgggaaac aagtctggag     1020

atgtaaaata tgtgacttac atggttaatg tacttgaaca tgcttccatt tctaaaggac     1080

tacaggatca gatagtgtct ctgggtgcca cagtacactt tacctgcgac gttcatggga     1140

acccagcccc caactgtacc tggtttcaca atgcacagcc tattcatcct tctgcacgac     1200

atctaactgc aggaaacgga ctgaaaatca gtggggttac tgtggaagat gttgggatgt     1260

atcagtgtgt agcagataat gggattggat ttatgcactc tactggaaga cttgaaattg     1320

aaaatgacgg tggattcaag ccagttataa ttacggcacc agtaagtgca aaggttgcag     1380

acggagactt tgttactctg tcctgcaatg ccagtgggct gccggttccg gtcattcgtt     1440

ggtatgacag ccatggattg ataaccagcc atccatctca agtcctgaga tcgaaatccc     1500

gaaaatcaca gttatcaaga cctgagggct tgaacctgga gcctgtgtac ttcgtcctgt     1560

cccaagctgg tgcaagctct ctccatattc aggctgtgac tcaggaacat gcggggaaat     1620

acatctgcga agctgcaaat gaacatggta ccacacaggc agaagcatct ctcatggttg     1680

ttccttttga aacaaataca aaagcagaga cagtcacact tcctgatgct gctcagaatg     1740

atgacagaag taagagagat ggttcagaaa ctgggttact gagctcattt ccggtgaagg     1800

tccatcccag tgcagtggaa tcagcaccag agaaaaacgc cagcggcatc tctgttcctg     1860

atgcccccat catactgagc cccccacaga cccacacacc agacacgtac aacctggtgt     1920

ggagggcagg caaggatggt gggctgccca tcaatgctta ctttgtgaag tatcgaaagc     1980

tggatgatgg ggttggcatg ctgggaagct ggcacacggt tcgagtccca ggaagtgaaa     2040

atgagctcca tttagctgag ctggagccat ctagtcttta tgaagtcttg atggtagcaa     2100

gaagcgcagc aggtgaaggc caacctgcca tgcttacctt ccgaaccagc aaagaaaaaa     2160

cagcgtcatc aaaaaacacc caggcatcct ctccacccgt gggcatccct aagtatcccg     2220

ttgtttcaga ggctgcaaac aacaattttg gagtggtact tacagattcc tctaggcaca     2280

gtggagttcc agaggcacca gatcggccta ccatctccac tgcatcagag acatcagtct     2340

atgtcacttg gattcctcgg gcaaacgggg gttctccaat cactgccttc aaagtcgaat     2400

ataaacggat gaggaccagc aattggctgg tggcagctga agacatccct ccttccaaac     2460

tttcagtgga agttcgtagt ttagaaccag gttcaacata caaatttagg gtcattgcca     2520

tcaaccatta tggtgagagt tttcggagtt cagcatctcg tccttatcaa gtggttgggt     2580

tccccaatcg cttttccagc cgtccaataa ctggacctca cattgcatac acagaggctg     2640

tcagcgatac tcagatcatg ctaaagtgga cgtacattcc atcaagtaac aataacactc     2700

ccattcaagg attttatatc tattaccgac caacagatag tgacaatgac agtgattaca     2760

agagggatgt tgtagaaggt tcaaagcagt ggcacatgat tggccacctg cagccagaaa     2820

cctcctatga cattaaaatg caatgcttca atgaaggagg agaaagtgaa tttagcaatg     2880

tgatgatctg cgagactaaa gtgaaacgtg ttcctggagc ttctgaatat cctgtcaaag     2940

acttgagtac ccctccaaat tctttgggaa gtggaggaaa tgtggggcct gcaaccagcc     3000

ctgccagaag cagtgacatg ttatatctga tcgttggctg tgtgctgggc gtcatggtcc     3060

tcattctgat ggttttcatt gcaatgtgcc tgtggaagaa tcgccagcag aataccatac     3120

aaaaatatga cccaccagga tatctctacc aaggatcaga tatgaacggg cagatggtgg     3180

actacaccac tctctcagga gcaagtcaga taaatggaaa tgttcacgga ggcttcctaa     3240

ccaatggcgg tctcagcagt ggctattccc accttcacca taaggtcccc aatgcagtca     3300

atggaattgt gaatgggagc ctaaatggag ggctttactc cgggcacagc aactctctaa     3360

ccaggacaca cgtggatttt gaacatcctc atcatctagt gaatggtggt ggaatgtaca     3420

cggccgtgcc tcagattgac cctctggagt gtgttaactg ccgaaattgt cgaaacaaca     3480

ataggtgttt caccaaaacc aacagcactt tcagcagcag ccctcctcct gtggtccctg     3540

tggtagcacc ttatcctcag gatggtttgg aaatgaagcc cctcagtcac gtgaaggtgc     3600

ctgtatgcct gacttccgca gtccctgatt gtggccagtt gccggaggag agcgtcaagg     3660

acaatgtgga accagtccct actcagcgta cctgctgtca ggacattgta aatgacgtca     3720

gctctgatgg ctcagaagat ccagcagagt tcagcagagg agacagctgt gcccattcag     3780

aaacagagat caacattgta agttggaatg ctcttatttt gccacctgtc cccgagggct     3840

gtgctgagaa gacaatgtgg tctccacctg gcattccttt agacagcccg acagaggtcc     3900

ttcagcagcc ccgggaaacc tgaggacatg caaacaacca gtcatgttcc aacttcaagc     3960

cggtaactgc acacaacagg cctgggagcg aactgtgtga aggaccttaa ttcaaatcag     4020

agaaaatcat tatttatttt tttgtagtag taatgtcata tgaatgtatc ttaaaacgtg     4080

tgccctttta tattatttat gccttaaatg ttttcttccc cattccttcc tccccctcgg     4140

taggaaacaa ccttgttttg catagtattc agtcacctgg agggcagagg ggtccttcca     4200

tgttttctaa cagctatagt gacagcaaga gctcctcatg caaaggatcc catctcttgg     4260

ctgcttcggc taggagggaa tgcaggggcc cgttgaaggt tgccaccagc tgggttttca     4320

ggtggaaaat ggtctttcaa tagtgtattc tcagactttt ttttgtttgt tttttgagat     4380

ggagtcttgc tgtcatccag gctggagtgc aatggctcga tcttggctca ctgcaacctc     4440

cgcctcccag gttcaagcaa ttctcccgcc tcagcctcct gagtagctgg gactacaggc     4500

acctgccacc acgtccagct aattgtcttg tatttttatt agagacaagg tttcaggctg     4560

gttttgaact cctgacctca agtgatccac ccgcctccgc ctcccaaagt gcgaggatta     4620

caggcgtgag ccaccacgtc tggcctgtat tatcagactt cctgagaaca ctttgaaatc     4680

aactgcagtt gtgacccatg tttataataa cagacctggc tgacggattt tacaagagtg     4740

ccttccacag aagtggtaat gtgacctgtt gactttgtat ctgcacgtgg gcacgagtga     4800

tgttcagttt gctaggcact agtcatagtg ttatggacgt ggtggagtgt aaggtcttga     4860

tgaattacgg cagtatgcag aaaaggaacc aaggccagag agacaaataa tgcctcatgt     4920

cccactgctt taaaattaca ttaatttata aaatggccac tatgggctct ttttgactgt     4980

ttctcggagt aggaacaaaa taagacatta aatggtggct tgaagagaaa gatacacatt     5040

ttcagaagaa agaaagggga gggctgcagg gagcctgtct tggcgggagc tctccagtct     5100

gttggattag cacagggaca cgcttatggt gccatgacgc cgaaactagt catcccccat     5160

ctccagcata ggcaacggcc tgcaggggtg agtgtcagaa aagacttact ttggaagaaa     5220

agggtttttt tttgtttgtt tgttttttgt ttttttttgt ttgtttgttt tgggtttttt     5280

tcctgaaatt tcctgatacc tttttcagaa tgtcaccctt gtaaataggc acctaaagcc     5340

aagttggtca gcagagctcc tgaccacggc tgcctctgcg tgacaaggac atttgcagct     5400

gcctttggaa ggctcttcac attaaaaaac aataattatg taagtgtgtt tcatagcttg     5460

agtcaagctt tcaaggatca ctgctccttt gtgcattgtg catccctttg gggaaagaaa     5520

cagaaaatta ttctctttct atagagtcaa gcaattccag cagaagtgaa gaaatgttag     5580

tttcccagaa atcgcagtgg aatagaatac aatactgtgt taaccaactt tctgtataaa     5640

tgcatcagta ttcccttaca tatgtctata tattttataa tagaactgtt agtgaaaatg     5700

tgcttgttta agctgggtca ctatgcaaga gttacttcca gtagaatgta gtgaatgtaa     5760

ttccctagtc ggatattagg gatgctgtag acccaagttc tacattccag atgtccgtgc     5820

ctatagtata ctggatttat tcttcatgtt gcttaaatgc agttagctct ggagggggat     5880

agctgcatcc cttacttctg tgactagcaa aggacaaagt cccagcgcac agaatatgaa     5940

aacataccct gtgttagcca atcaagttac agcaatgctg tcacaaaggg agttttagaa     6000

aactggggag tcattgtccg tagacagcca ttttgattta ggaaacaggt gtattagcat     6060

gagccttagg tcatgaactg cttttaaaga ttgagtttga atatgggatc tgtccacgag     6120

gaagagaaaa tggctttacc tttaggacaa tctcattgtg gactgcttta tttatattat     6180

tagtaacgct gttttaagtg ttattctttt tattgtattt tatttataaa aaatgccttt     6240

atatattgaa atatataaat atatatatat aaacacacac acacacacac acacacacat     6300

atatatatat atatataatt gcctttatat ttaggcggta tgagttctcc ctaagcgtga     6360

gttggctctg ccctgcacag gcacccaaac agtcctacct aatgtcactt caccaggaaa     6420

tgagaggaca tggtacagtg tgggagacag cactaacacg tgctgaataa ctactgtgta     6480

ccaggcactg tgctcggtgc ttgttactgt taactcattt aacccccaca actcatctac     6540

aaagttggca ttaaaatccc caagtcactc agtgagccat gggacctgaa tccgaaccta     6600

gtttatctgg agccataatc tgggctcctc ccatttttcc atactgcttt ccaaaagcat     6660

tgtggttcac tctttggatg gaaccagtcc cgttccgtat gctgtgatct atccctgccg     6720

tggaattcct ccgaggctcc aactccgcag ccagagaagc tgctctctgg cctccgcggg     6780

cagagctctg cttatgactt cgtcttccag aggtccacat ttctcccctt gacgccccct     6840

gtctaccacc tccacctgga aatttgatct ttactgtgct cagtgatcac gaaattggtc     6900

aagcctattc atgttccttc tcatctagaa ttctgtgtga ttgttttagc ataaactgcc     6960

ccgctcccac tgtatcattt cacgatctcc ttttaatgtt tttctttcag ttttgcactg     7020

acagtctggt gacaggtgct gccagggtgc aagttacatt gcaatgttct aaaccttttg     7080

aagtgttctt agcaaaagcc tttctttctg ggtgtttttg tcgaatgagt ctatgaagac     7140

tcaatgcatc catcttgggc tgatcatgcc acagatctca ttccagctat agtactgcca     7200

agaagtgaag tttatcattg aattttacct gtgttgctct cttttaaagt aatgactttg     7260

agatgcatgc tttgtatcat attgaaaagt atgttttatt ttccttaaag ttgtaatatt     7320

gtgtgtgaaa ctgtacatat tttaaatgat gtagctttgg caggttttat ttggttgata     7380

tgattttata ttaaaagaga aggctgcttt catatagcat agcccctgaa ggtgggaata     7440

ctccctgttt gtacaacgct gcttatagtt tgtgattggg gtgggcgaat gtcttcctct     7500

gaaattcttt ggaacccccc acccctgtcc tcccctgaaa ctcccctgtg cacacccctc     7560

tgttctgact gcagagatca aggccctgaa ggagcaggat cttgggcaag tgttttaggg     7620

gacgctgaga acatacctga ccctgggggc gatgtggagg caggcccacc tcctcggggc     7680

aactttgcgt ttccttggag ggaagggagg tgggtaggag aggagcttgg gaggatgagg     7740

aggagcggtc ccgcctcaca cattgtctat ttttaccatt aaccgagcgc cacatgttta     7800

tgaacttcag gatagaaatt tagcctcctt gtgaaaacgt tttgttttac tgccctaaga     7860

aaatacacat ctctaggctt gtctgaccag aaagccagca aagtcttttg catcgggtgt     7920

ggcccttttg tattttattt cccatattta aataagcctt ccttaaaccc tagccccagt     7980

cctgagagct ttgagggtag ccgaaacccc ttatctaata aagtctaact ctgtgagaac     8040

cacagaaaaa a                                                          8051


<210>  406
<211>  3784
<212>  DNA
<213>  homo sapiens

<400>  406
gcaggccggc gctcccattg gccgggatgg cggcggcggc gcgcgcggcc ccggcgagca       60

ggggaagccg gtggccgcgg ctgcggaacg ggcggaggct gccggtttcg taaccgtcgc      120

tcctcctcgc tgactcgcgg gctgtgaggc ctgggtcggc tcgggccgca ccgcgcgggg      180

ccgctcggag tggaggccgc ctgggggcag gcgggctaga ggagcaggta catgtgaaga      240

ttttttggca gcttagcgtg gaaaccattg atcaccctgc tctcatttct acctgttctg      300

tgttggcaag ggagagtgcc caaatgagca agatatcgca gcaaaacagc actccagggg      360

tgaacggaat tagtgttatc catacccagg cacatgccag cggcttacag caggttcctc      420

agctggtgcc tgctggccct gggggaggag gcaaagctgt ggctcccagc aagcagagca      480

aaaagagttc gcccatggat cgaaacagtg acgagtatcg gcaacgccga gagaggaaca      540

acatggctgt gaaaaagagc cggttgaaaa gcaagcagaa agcacaagac acactgcaga      600

gagtcaatca gctcaaagaa gagaatgaac ggttggaagc aaaaatcaaa ttgctgacca      660

aggaattaag tgtactcaaa gatttgtttc ttgagcatgc acacaacctt gcagacaacg      720

tacagtccat tagcactgaa aatacgacag cagatggcga caatgcagga cagtagacct      780

caccctttcc agactttaga gcttgtggct tgaatgttaa aggtgtgacc accgacacca      840

ctcatgtcaa tggctgaaag ttgtccattt ccatgactca aagacccatt ggaggctatt      900

ttctgggatc agcactgaag agttgattag ctaaaaatgt tagccttgta attcgaatat      960

ctggttttaa atgatagagg tttttgtggg aatcaaaatc ccccaaatgt taaggtatat     1020

ggtaaaaaaa gaaatatctg ggatcccgat gttcttaata aatcctgact tcccaagaaa     1080

tgcttctttt ttaagttgac aaaaggaatg gggaactggc aggccgcgca gaaggttctt     1140

ggttttaatg gataggctga attggattaa gaaaagttga atgccaccta tggtaatcta     1200

tttgtgattt tcttctaaat tatgtattat aaattcgtag agctatagaa agcaatgagt     1260

gtgtaatttg gagtgatttt atatatggca taaactttgt tttaacataa ttagtactgt     1320

tttcccccaa aagtacaagt ttttgagtag caatgtcagg ttaagtaaag aaacttcatc     1380

acatcttata ggtagtgtgt ggccaattga cttaaaaaat acaaataaca tttaggaagc     1440

aaatagatta aacacaaaaa taaaactaaa gcataggaat tatgtttttg agataccttt     1500

gggcttagat tggcattgtt ttattctaaa aacccaactc agtggtgtag agaaacttgt     1560

gtaccaaaat tttagtttct gcagatgcta gtgttttttt ggatacaatt ttgacaacca     1620

agttagtaaa caaaatatct taacagtttg atgacacaag ctactgatga gggtttggaa     1680

tattaattca gaaggtagtt tctcttgtgt tcaaaatagc tgccatgggg ctgttacttt     1740

taaagtcaaa attttcttct gaaggctcat tttggtattt gatcttaacc aagtgattat     1800

tagagaaatg tatcaactcc atgccatctc ccaaaataat tgtctaagaa aacttgaaag     1860

tgtaaggttt taacctttaa tttatttctc ttaaatacat cttttgatat tgttgttgtg     1920

acatttcttt ttctggttag tgggctttcc agactttgta ccactgcttc tgtttattca     1980

tttatatgct tttgtgtccc ataaattatt tcagaaaatg ctgataaaac tcaggatatt     2040

gacatttttg ttgagactaa aaaatggcag tcgctaaagt agggactcta gagtctggct     2100

tacgtcagtg ttggtagttt agattgtctt tgtcaacgtt ttttcttctc tcttttgctt     2160

tcttttcttt ctcttttttt cttagcacag ttctagctca aatttgtgta ttttttgtgt     2220

gcctgggctg gagatgagag actgagtcat aactgattta aaagtttgtg ttatcaggta     2280

tcttatttga acatggtcat ttttggccac attgctgttt catactagga cttgggatga     2340

tgtagccaga ataaaactca agttgcaccc tccggttggt ggaagattgc tgaccgtgcc     2400

gtttctgggc aggagaagac atcatggtgt ccagcaactc agcaaagcca ttcttaagag     2460

tcgtgaggtc cttctgaatg taaaactgga gcccaggaga agctgtccca ggagggctgt     2520

taactcccta tagagccagg agacaggata ggggtttcta gggtccaaca ccagcttacc     2580

ttggagtatg aatctaccca tgaaggatga gagatgtttt gaaaaactag ccaggacaca     2640

cccacaggat cctactggct ccttagcagc tgattggtgt tacataatta acttaattgg     2700

agatgcatta ggtcacttga atgtataagc aagcacctat ggtaggcgct acagacattt     2760

aaatctcttg ggaattcgat gctcccatgg aatttatacc agttatatga attgacttaa     2820

gtatcttgaa aaagaaactt tagagaaagc atcaggggtg tgtactcagt atttcaaatc     2880

agaacacaag attggaactt ttggaaaaat gggttcaagc tttcctatta gccatggaaa     2940

tgcaaagttt agcagaagca agcaattagg cagagaacaa aaatgttaag catggtgttg     3000

tctatcttat tgaagtggtt ggaaatgaaa gcttttaatt tgatagattt atcagtataa     3060

aattagggaa accacgtgtg gggaatgaat caatttagag cttcgggaat tgtgaggtga     3120

cttttgtaac ttttgttctg tgtgtgacct gtgaaccact aggatgtgat ctgcccttgt     3180

gggcaggtcc agcatagtta ggagttaggc tttagcataa atttctagct gcatctgagt     3240

ctcctgggat gggtgctctt tggctggttt tggctgcgga tggtgagatc agagcagctc     3300

ttcctgctgc tggcccctgc aatcagttgt tgggatgcca gtgcagatca ctaagtagta     3360

agattttaat caaacacgac caggtccgaa atgcaggtca tgagtgtgaa attctcaaat     3420

ttacataaaa agtagaagta tagacagttt aacatttggt attaaaggag aggaaattgt     3480

agcagctttt cacgtttccc agtccccatt agagggcttg agaccttgta cctgaacaac     3540

ccattttgca ctcagtgctt tctgatgcct taggagaatt gttttgtttc acaaaagctg     3600

ggaaggaaga agtccattct gcagctgtta gatctgcctc tcaggaaaaa gtactaactt     3660

gttctttttg ttcctggctt tcatcagttt gtgagatttc tctatttttt ttaaatataa     3720

ttttatttct ttcaacaaat ataaaataaa aaacaacttt ggaacaatga aaaaaaaaaa     3780

aaaa                                                                  3784


<210>  407
<211>  1902
<212>  DNA
<213>  homo sapiens

<400>  407
ggcactgggc aggaagggga gggggagcga gcgcgagaaa tgcagaggct gcagcggcgg       60

cggcggcggc agtagcggca gcggcgacga cggcggcggc agcgctccaa ctggctcctc      120

gctccgggct ccgccgtcga gccgggagag agcctccgcc agcggccagg caccagccag      180

acgacgccag cgaccccggc ctctcggcgg caccgcgcta actcaggggc tgcataggca      240

cccagagccg aactccaaga tgggaggcaa gctcagcaag aagaagaagg gctacaatgt      300

gaacgacgag aaagccaagg agaaagacaa gaaggccgag ggcgcggcga cggaagagga      360

ggggaccccg aaggagagtg agccccaggc ggccgcagag cccgccgagg ccaaggaggg      420

caaggagaag cccgaccagg acgccgaggg caaggccgag gagaaggagg gcgagaagga      480

cgcggcggct gccaaggagg aggccccgaa ggcggagccc gagaagacgg agggcgcggc      540

agaggccaag gctgagcccc cgaaggcgcc cgagcaggag caggcggccc ccggccccgc      600

tgcgggcggc gaggccccca aagctgctga ggccgccgcg gccccggccg agagcgcggc      660

ccctgccgcc ggggaggagc ccagcaagga ggaaggggaa cccaaaaaga ctgaggcgcc      720

cgcagctcct gccgcccagg agaccaaaag tgacggggcc ccagcttcag actcaaaacc      780

cggcagctcg gaggctgccc cctcttccaa ggagaccccc gcagccacgg aagcgcctag      840

ttccacaccc aaggcccagg gccccgcagc ctctgcagaa gagcccaagc cggtggaggc      900

cccggcagct aattccgacc aaaccgtaac cgtgaaagag tgacaaggac agcctatagg      960

aaaaacaata ccacttaaaa caatctcctc tctctctctc tctctctctc tctatctctc     1020

tctctatctc ctctctctct ctcctctcct atctctcctc tctctctctc ctatactaac     1080

ttgtttcaaa ttggaagtaa tgatatgtat tgcccaagga aaaatacagg atgttgtccc     1140

atcaagggag ggagggggtg ggagaatcca aatagtattt ttgtggggaa atatctaata     1200

taccttcagt caactttacc aagaagtcct ggatttccaa gatccgcgtc tgaaagtgca     1260

gtacatcgtt tgtacctgaa actgccgcca catgcactcc tccaccgctg agagttgaat     1320

agcttttctt ctgcaatggg agttgggagt gatgcgtttg attctgccca cagggcctgt     1380

gccaaggcaa tcagatcttt atgagagcag tattttctgt gttttctttt taatttacag     1440

cctttcttat tttgatattt ttttaatgtt gtggatgaat gccagctttc agacagagcc     1500

cacttagctt gtccacatgg atctcaatgc caatcctcca ttcttcctct ccagatattt     1560

ttgggagtga caaacattct ctcatcctac ttagcctacc tagatttctc atgacgagtt     1620

aatgcatgtc cgtggttggg tgcacctgta gttctgttta ttggtcagtg gaaatgaaaa     1680

aaaaaaaaaa aaaaagtctg cgttcattgc agttccagtt tctcttccat tctgtgtcac     1740

agacaccaac acaccactca ttggaaaatg gaaaaaaaaa acaaaaaaaa aacaaaaaaa     1800

tgtacaatgg atgcattgaa attatatgta attgtataaa tggtgcaaca gtaataaagt     1860

taaacaatta aaaagaagta ataaagacaa aaaaaaaaaa aa                        1902


<210>  408
<211>  4923
<212>  DNA
<213>  homo sapiens

<400>  408
gcacgcggtt ctccctgatc ccggagctgg gctcagggct cggactcagt cctgcagcgc       60

ctctaggctg cggatccgcg cttcaaccac ctgctttgcg ctgcgtccgg ggaagtgggg      120

aggagacggg agggagggag gaggcgggga gaggaggaaa gaggcagctt acacacgcct      180

tccagtccct ctactcagag cagcccggag accgctgccg ccgctgccgc tgctaccacc      240

gctgccacct gaggagaccc gccgcccccc cgtcgccgcc tcctgcgagt ccttcttagc      300

acctggcgtt tcatgcacat tgccactgcc attattatta tcattccaat acaaggaaaa      360

taaaagaaga taccagcgaa aagaaccgct tacacctttc cgaattactc aagtgtctcc      420

tggaaacaga gggtcgttgt ccccggagga gcagccgaag ggcccgtggg ctggtgttga      480

ccgggaggga ggaggagttg ggggcattgc gtggtggaaa gttgcgtgcg gcagagaacc      540

gaaggtgcag cgccacagcc caggggacgg tgtgtctggg agaagacgct gcccctgcgt      600

cgggacccgc cagcgcgcgg gcaccgcggg gcccgggacg acgccccctc ctgcggcgtg      660

gactccgtca gtggcccacc aagaaggagg aggaatatgg aatccaaggg ggccagttcc      720

tgccgtctgc tcttctgcct cttgatctcc gccaccgtct tcaggccagg ccttggatgg      780

tatactgtaa attcagcata tggagatacc attatcatac cttgccgact tgacgtacct      840

cagaatctca tgtttggcaa atggaaatat gaaaagcccg atggctcccc agtatttatt      900

gccttcagat cctctacaaa gaaaagtgtg cagtacgacg atgtaccaga atacaaagac      960

agattgaacc tctcagaaaa ctacactttg tctatcagta atgcaaggat cagtgatgaa     1020

aagagatttg tgtgcatgct agtaactgag gacaacgtgt ttgaggcacc tacaatagtc     1080

aaggtgttca agcaaccatc taaacctgaa attgtaagca aagcactgtt tctcgaaaca     1140

gagcagctaa aaaagttggg tgactgcatt tcagaagaca gttatccaga tggcaatatc     1200

acatggtaca ggaatggaaa agtgctacat ccccttgaag gagcggtggt cataattttt     1260

aaaaaggaaa tggacccagt gactcagctc tataccatga cttccaccct ggagtacaag     1320

acaaccaagg ctgacataca aatgccattc acctgctcgg tgacatatta tggaccatct     1380

ggccagaaaa caattcattc tgaacaggca gtatttgata tttactatcc tacagagcag     1440

gtgacaatac aagtgctgcc accaaaaaat gccatcaaag aaggggataa catcactctt     1500

aaatgcttag ggaatggcaa ccctccccca gaggaatttt tgttttactt accaggacag     1560

cccgaaggaa taagaagctc aaatacttac acactgacgg atgtgaggcg caatgcaaca     1620

ggagactaca agtgttccct gatagacaaa aaaagcatga ttgcttcaac agccatcaca     1680

gttcactatt tggatttgtc cttaaaccca agtggagaag tgactagaca gattggtgat     1740

gccctacccg tgtcatgcac aatatctgct agcaggaatg caactgtggt atggatgaaa     1800

gataacatca ggcttcgatc tagcccgtca ttttctagtc ttcattatca ggatgctgga     1860

aactatgtct gcgaaactgc tctgcaggag gttgaaggac taaagaaaag agagtcattg     1920

actctcattg tagaaggcaa acctcaaata aaaatgacaa agaaaactga tcccagtgga     1980

ctatctaaaa caataatctg ccatgtggaa ggttttccaa agccagccat tcaatggaca     2040

attactggca gtggaagcgt cataaaccaa acagaggaat ctccttatat taatggcagg     2100

tattatagta aaattatcat ttcccctgaa gagaatgtta cattaacttg cacagcagaa     2160

aaccaactgg agagaacagt aaactccttg aatgtctctg ctataagtat tccagaacac     2220

gatgaggcag acgagataag tgatgaaaac agagaaaagg tgaatgacca ggcaaaacta     2280

attgtgggaa tcgttgttgg tctcctcctt gctgcccttg ttgctggtgt cgtctactgg     2340

ctgtacatga agaagtcaaa gactgcatca aaacatgtaa acaaggacct cggtaatatg     2400

gaagaaaaca aaaagttaga agaaaacaat cacaaaactg aagcctaaga gagaaactgt     2460

cctagttgtc cagagataaa aatcatatag accaattgaa gcatgaacgt ggattgtatt     2520

taagacataa acaaagacat tgacagcaat tcatggttca agtattaagc agttcattct     2580

accaagctgt cacaggtttt cagagaatta tctcaagtaa aacaaatgaa atttaattac     2640

aaacaataag aacaagtttt ggcagccatg ataataggtc atatgttgtg tttggttcaa     2700

ttttttttcc gtaaatgtct gcactgagga tttctttttg gtttgccttt tatgtaaatt     2760

ttttacgtag ctatttttat acactgtaag ctttgttctg ggagttgctg ttaatctgat     2820

gtataatgta atgtttttat ttcaattgtt tatatggata atctgagcag gtacatttct     2880

gattctgatt gctatcagca atgccccaaa ctttctcata agcacctaaa acccaaaggt     2940

ggcagcttgt gaagattggg gacactcata ttgccctaat taaaaactgt gatttttatc     3000

acaagggagg ggaggccgag agtcagactg atagacacca taggagccga ctctttgata     3060

tgccaccagc gaactctcag aaataaatca cagatgcata tagacacaca tacataatgg     3120

tactcccaaa ctgacaattt tacctattct gaaaaagaca taaaacagaa tttggtagca     3180

cttacctcta cagacacctg ctaataaatt attttctgtc aaaagaaaaa acacaagcat     3240

gtgtgagaga cagtttggaa aaatcatggt caacattccc attttcatag atcacaatgt     3300

aaatcactat aattacaaat tggtgttaaa tcctttgggt tatccactgc cttaaaatta     3360

tacctatttc atgtttaaaa agatatcaat cagaattgga gtttttaaca gtggtcatta     3420

tcaaagctgt gttattttcc acagaatata gaatatatat ttttttcgtg tgtgtttttg     3480

ttaactaccc tacagatatt gaatgcacct tgagataatt tagtgttttt aactgataca     3540

taatttatca agcagtacat gaaagtgtaa taataaaatg tctatgtatc tttagttaca     3600

ttcaaatttg taactttata aacatgtttt atgcttgagg aaatttttaa ggtggtagta     3660

taaatggaaa ctttttgaag tagaccagat atgggctact tgtgactaga cttttaaact     3720

ttgctctttc aagcagaagc ctggtttctg ggagaacact gcacagcgat ttctttccca     3780

ggatttacac aactttaaag ggaagataaa tgaacatcag atttctaggt atagaactat     3840

gttattgaaa ggaaaaggaa aactggtgtt tgtttcttag actcatgaaa taaaaaatta     3900

tgaaggcaat gaaaaataaa ttgaaaatta aagtcagatg agaataggaa taatactttg     3960

ccacttctgc attatttaga aacatacgtt attgtacatt tgtaaaccat ttactgtctg     4020

ggcaatagtg actccgttta ataaaagctt ccgtagtgca ttggtatgga ttaaatgcat     4080

aaaatattct tagactcgat gctgtataaa atattatggg aaaaaaagaa aatacgttat     4140

tttgcctcta aacttttatt gaagttttat ttggcaggaa aaaaaattga atcttggtca     4200

acatttaaac caaagtaaaa ggggaaaaac caaagttatt tgttttgcat ggctaagcca     4260

ttctgttatc tctgtaaata ctgtgatttc ttttttattt tctctttaga attttgttaa     4320

agaaattcta aaatttttaa acacctgctc tccacaataa atcacaaaca ctaaaataaa     4380

attacttcca tataaatatt attttctctt ttggtgtggg agatcaaagg tttaaagtct     4440

aacttctaag atatatttgc agaaagaagc aacatgacaa tagagagagt tatgctacaa     4500

ttatttcttg gtttccactt gcaatggtta attaagtcca aaaacagctg tcagaacctc     4560

gagagcagaa catgagaaac tcagagctct ggaccgaaag cagaaagttt gccgggaaaa     4620

aaaaagacaa cattattacc atcgattcag tgcctggata aagaggaaag cttacttgtt     4680

taatggcagc cacatgcacg aagatgctaa gaagaaaaag aattccaaat cctcaacttt     4740

tgaggtttcg gctctccaat ttaactcttt ggcaacagga aacaggtttt gcaagttcaa     4800

ggttcactcc ctatatgtga ttataggaat tgtttgtgga aatggattaa catacccgtc     4860

tatgcctaaa agataataaa actgaaatat gtcttcacag gtctcccaca aaaaaaaaaa     4920

aaa                                                                   4923


<210>  409
<211>  2666
<212>  DNA
<213>  homo sapiens

<400>  409
ggggcggacg ccgctcgccg gctggcccca tcctccactg cagcagtaac gtcgcggcgg       60

gttgcgggta ggactggacg ccagagcagc cgcgcagcgc ctgaaccgct gcgggccgcc      120

gcggccgccc cttcccaccc tcgcctctgc tgtctccagc ctcgcttctc cgactttcct      180

gctcctctgc tgccttcgtt tctggtcctc ggccgtcctc gccgcccgcc cagaggagtc      240

cccgcgcccg ccaagaagcc gctttccgct ggcccgcagc cgccgcgact tcggcacagt      300

ttctccctct ggctagtctc ccaaacggcc gctcctcgcc cgcgggaaga ccaggctgcg      360

accgcgaacg cccgatcctc tccaggagcc gcagcgagcg cccggcggcc acgccccgcg      420

accacacccc ggcggctctc ggcccagcgc gcctgccttc gccgcccgcc gtcgctcctc      480

gcccgctgca cgacgacgcg acgcccctgc tgcaggcggc ggacccgacc ggacccagac      540

ccagacgcaa gatggcgacg gccgcgtgac tgcctcagcg tccccgagct cggctccgag      600

tgcacctacg gactgactgt gggggcagag aagggcgaga tcaggactct gtctttgtta      660

atcgtgactg catgaaggtc gcctccctcg ggcctacttg gtgggagtgt ctggtattgt      720

tctaaggcca ggagcacggt gagccacagt ctgttggtag aatttggcgt cttgatagtt      780

gagaaaatgg cgatgacact gttggaagac tggtgccggg ggatggatgt gaactcccag      840

agagctctgt tagtctgggg catcccagtg aactgtgatg aggctgaaat cgaagagacc      900

ctccaggctg cgatgcccca ggtctcctac cgaatgcttg ggagaatgtt ctggagggaa      960

gaaaatgcga aagcagcctt attagagctc actggcgctg tagattacgc cgcgatcccc     1020

agggagatgc cgggcaaagg aggggtctgg aaagtgttat ttaagccccc aacttctgat     1080

gctgaatttt tagaaagatt gcacctcttc ctagctagag aggggtggac cgtgcaagat     1140

gttgcccgtg tccttgggtt tcagaaccct actccgaccc cgggcccaga gatgccagca     1200

gagatgctaa actatatttt ggataatgtt attcagcctc ttgttgagtc catatggtac     1260

aagaggctga cacttttctc ggggagggac atcccagggc ctggagagga aacctttgat     1320

ccctggctgg agcacactaa tgaggtccta gaggagtggc aggtgtccga tgtagaaaag     1380

aggcggcggt tgatggagag tcttagaggc cccgccgctg atgttattcg catccttaag     1440

tccaacaacc ccgcgataac cactgccgaa tgcctgaagg cgcttgagca ggtgtttggg     1500

agcgttgaga gctctaggga tgcccagatc aaatttctga acacttatca gaacccggga     1560

gaaaaattgt ctgcttatgt cattcgtctg gagcctctgc tacagaaggt ggtagagaag     1620

ggggccattg ataaagataa tgtgaaccag gcccgcctag agcaggtcat tgccggggcc     1680

aaccacagcg gggccatccg aaggcagctg tggcttaccg gggctgggga agggccagcc     1740

ccaaacctct ttcagttgct ggtgcagatc cgtgaggagg aagccaagga ggaggaggag     1800

gaggctgagg ccacccttct gcagttaggc ctggaagggc acttctgagt gccaggaaag     1860

gcagctttag tgcagaccta gatcacagct acttttcttg tccctgtggg gtcttacaga     1920

tgtgtctctg agtagtaaag gcttagcctt gttctgtttt gttgtttttt ggaggggaag     1980

gttagtcagg cctgagtatt catgtaacat tctaaaattg tgccagcgag caccgtgaac     2040

gactgcaatg caagcgggtc ttgctggcta aaatgccagg taaagggttg gttggacaca     2100

gcgcttagtg cacgctgtca tcatggacat cataatcagt tgtgaaaaac acgcgaacct     2160

atgacacttc ttattccaca ctgaatgtga aattgcatgt tcagatgttt actacgaggc     2220

ctggctcaca ggaagtgttc agtaaaagta tgcactgtta gattactgat aacgcggata     2280

gatttttgtt taccataaat tgttccagat ttatattaat ggaaggaagt gtgcatttat     2340

tagctattac tcaactttac aatgcaaaca tcttatttct catctttaaa catgtcgacc     2400

agtttaattg aaaagtattc tgagactgca aaatggggtg ttaaaaaata ctgcagttac     2460

ggagctgtgt aaaccagttt ctcattgcat aagatacaga tgtaaattgc atggagaggt     2520

tgatatgcac ctgtacagta attcactccc ccatttcaca tctttgtcag agaatagttc     2580

ttgttcatac tgagtgttct aaatttgaag ttatatatac aaattaaaat attttaaaaa     2640

ttcaaaaaaa aaaaaaaaaa aaaaaa                                          2666


<210>  410
<211>  2033
<212>  DNA
<213>  homo sapiens

<400>  410
cggccccccg cattccccgc ccccacctcc ccgccttgtt gtccaacttc tcccggagca       60

gccggagagc aggcgtcggg acgcagcaaa gagaggagag gccaccatgg cggagctgca      120

ggaggtgcag atcacagagg agaagccact gttgccagga cagacgcctg aggcggccaa      180

gactcactct gtggagacac catacggctc tgtcactttc actgtctatg gcacccccaa      240

acccaaacgc ccagcgatcc ttacctacca cgatgtggga ctcaactata aatcttgctt      300

ccagccactg tttcagttcg aggacatgca ggaaatcatt cagaactttg tgcgggttca      360

tgtggatgcc cctggaatgg aagagggagc ccctgtgttc cctttgggat atcagtaccc      420

atctctggac cagcttgcag acatgatccc ttgcgtcctg cagtacctaa atttctctac      480

aataattgga gttggtgttg gagctggagc ctacatcctg gcgagatatg ctcttaacca      540

cccggacact gttgaaggtc ttgtcctcat caacattgat cccaatgcca agggttggat      600

ggattgggca gcccacaagc taacaggcct cacctcttcc attccggaga tgatccttgg      660

acatcttttc agccaggaag agctctctgg aaattctgag ttgatacaaa agtacagaaa      720

tatcattaca catgcaccca acctggataa cattgaattg tactggaaca gctacaacaa      780

ccgccgagac ctgaactttg agcgtggagg tgatatcacc ctcaggtgtc ctgtgatgct      840

ggtggtagga gaccaagcac ctcatgaaga tgcagtggtg gaatgtaact caaaactgga      900

ccccacccag acctcgttcc tcaagatggc tgactccgga ggtcagcccc agctgactca      960

gccaggcaag ctgaccgagg ccttcaagta cttcctgcaa ggcatgggct acatggcctc     1020

atcctgcatg actcgcctgt cccggtctcg tacagcctct ctgaccagtg cagcatccgt     1080

tgatggcaac cggtcccgct ctcgcaccct gtcccagagc agcgagtctg gaactctttc     1140

ttcggggccc ccggggcaca ccatggaggt ctcctgttga atggcccttg ttgccctaga     1200

gtgggaccca gccctcacct cccccagagc taacctggga ggtgctgaag gggcattggg     1260

ccaccgtaag caagggaaaa agggcagatc atgcggggag atgaccttga tctttgattg     1320

ctaccctaac cttgaccttt aacccgtgat tccccccagc tcctggaaga gatgtcctaa     1380

tatctcttag ggacccagac ccctaaattc tcctcctccc ccattttgat gttaaggtgg     1440

agagggcata tgcatcctct gtcctgatct aggtgtctat agctgagggg taagaggttg     1500

ttgtagttgt cctggtgcct ccatcagact ctccctactt gtcccatatt tgcaagggga     1560

ggggatttgg ggctggggct ccattcacca aagctgaggt ggcttctcat taacccttta     1620

ggactctgaa gggtatggac ctacgtgaat gtgtgtcagg gggagacttg ctggtgggtt     1680

agtggtcctc aggatgtgat agaaacatcc agtgtaaaaa ggaagttgga atgggagttg     1740

gcgggcagtg aacgagtgtg gggaaggatt ggtgctgggg caacaggaag gggcctgggg     1800

ccgtttggct gcactaactt tggtagctca gtgtgcatct agagtgggac tggggaggga     1860

gctaagcttg ggctgggctg cttggggctt ggcatagggt ggaaagggct accctggggc     1920

tctgaccaca ctgtagtatg tgtggagggt gccctcccgt ctcccacaac ttctgctata     1980

acaataaact gtagaggaat ctgagtaccg ttaaaaaaaa aaaaaaaaaa aaa            2033


<210>  411
<211>  2100
<212>  DNA
<213>  homo sapiens

<400>  411
cggccccccg cattccccgc ccccacctcc ccgccttgtt gtccaacttc tcccggagca       60

gccggagagc aggcgtcggg acgcagcaaa gagaggagag accccagagt cagaaggagt      120

gagaaccctg acccctaatc ccactgcatc cagccaatag gagcccagcc accatggcgg      180

agctgcagga ggtgcagatc acagaggaga agccactgtt gccaggacag acgcctgagg      240

cggccaagac tcactctgtg gagacaccat acggctctgt cactttcact gtctatggca      300

cccccaaacc caaacgccca gcgatcctta cctaccacga tgtgggactc aactataaat      360

cttgcttcca gccactgttt cagttcgagg acatgcagga aatcattcag aactttgtgc      420

gggttcatgt ggatgcccct ggaatggaag agggagcccc tgtgttccct ttgggatatc      480

agtacccatc tctggaccag cttgcagaca tgatcccttg cgtcctgcag tacctaaatt      540

tctctacaat aattggagtt ggtgttggag ctggagccta catcctggcg agatatgctc      600

ttaaccaccc ggacactgtt gaaggtcttg tcctcatcaa cattgatccc aatgccaagg      660

gttggatgga ttgggcagcc cacaagctaa caggcctcac ctcttccatt ccggagatga      720

tccttggaca tcttttcagc caggaagagc tctctggaaa ttctgagttg atacaaaagt      780

acagaaatat cattacacat gcacccaacc tggataacat tgaattgtac tggaacagct      840

acaacaaccg ccgagacctg aactttgagc gtggaggtga tatcaccctc aggtgtcctg      900

tgatgctggt ggtaggagac caagcacctc atgaagatgc agtggtggaa tgtaactcaa      960

aactggaccc cacccagacc tcgttcctca agatggctga ctccggaggt cagccccagc     1020

tgactcagcc aggcaagctg accgaggcct tcaagtactt cctgcaaggc atgggctaca     1080

tggcctcatc ctgcatgact cgcctgtccc ggtctcgtac agcctctctg accagtgcag     1140

catccgttga tggcaaccgg tcccgctctc gcaccctgtc ccagagcagc gagtctggaa     1200

ctctttcttc ggggcccccg gggcacacca tggaggtctc ctgttgaatg gcccttgttg     1260

ccctagagtg ggacccagcc ctcacctccc ccagagctaa cctgggaggt gctgaagggg     1320

cattgggcca ccgtaagcaa gggaaaaagg gcagatcatg cggggagatg accttgatct     1380

ttgattgcta ccctaacctt gacctttaac ccgtgattcc ccccagctcc tggaagagat     1440

gtcctaatat ctcttaggga cccagacccc taaattctcc tcctccccca ttttgatgtt     1500

aaggtggaga gggcatatgc atcctctgtc ctgatctagg tgtctatagc tgaggggtaa     1560

gaggttgttg tagttgtcct ggtgcctcca tcagactctc cctacttgtc ccatatttgc     1620

aaggggaggg gatttggggc tggggctcca ttcaccaaag ctgaggtggc ttctcattaa     1680

ccctttagga ctctgaaggg tatggaccta cgtgaatgtg tgtcaggggg agacttgctg     1740

gtgggttagt ggtcctcagg atgtgataga aacatccagt gtaaaaagga agttggaatg     1800

ggagttggcg ggcagtgaac gagtgtgggg aaggattggt gctggggcaa caggaagggg     1860

cctggggccg tttggctgca ctaactttgg tagctcagtg tgcatctaga gtgggactgg     1920

ggagggagct aagcttgggc tgggctgctt ggggcttggc atagggtgga aagggctacc     1980

ctggggctct gaccacactg tagtatgtgt ggagggtgcc ctcccgtctc ccacaacttc     2040

tgctataaca ataaactgta gaggaatctg agtaccgtta aaaaaaaaaa aaaaaaaaaa     2100


<210>  412
<211>  2075
<212>  DNA
<213>  homo sapiens

<400>  412
cggccccccg cattccccgc ccccacctcc ccgccttgtt gtccaacttc tcccggagca       60

gccggagagc aggcgtcggg acgcagcaaa gagaggagag gccaccatgg cggagctgca      120

ggaggtgcag atcacagagg agaagccact gttgccagga cagacgcctg aggcggccaa      180

ggaggctgag ttagctgccc gaatcctcct ggaccaggga cagactcact ctgtggagac      240

accatacggc tctgtcactt tcactgtcta tggcaccccc aaacccaaac gcccagcgat      300

ccttacctac cacgatgtgg gactcaacta taaatcttgc ttccagccac tgtttcagtt      360

cgaggacatg caggaaatca ttcagaactt tgtgcgggtt catgtggatg cccctggaat      420

ggaagaggga gcccctgtgt tccctttggg atatcagtac ccatctctgg accagcttgc      480

agacatgatc ccttgcgtcc tgcagtacct aaatttctct acaataattg gagttggtgt      540

tggagctgga gcctacatcc tggcgagata tgctcttaac cacccggaca ctgttgaagg      600

tcttgtcctc atcaacattg atcccaatgc caagggttgg atggattggg cagcccacaa      660

gctaacaggc ctcacctctt ccattccgga gatgatcctt ggacatcttt tcagccagga      720

agagctctct ggaaattctg agttgataca aaagtacaga aatatcatta cacatgcacc      780

caacctggat aacattgaat tgtactggaa cagctacaac aaccgccgag acctgaactt      840

tgagcgtgga ggtgatatca ccctcaggtg tcctgtgatg ctggtggtag gagaccaagc      900

acctcatgaa gatgcagtgg tggaatgtaa ctcaaaactg gaccccaccc agacctcgtt      960

cctcaagatg gctgactccg gaggtcagcc ccagctgact cagccaggca agctgaccga     1020

ggccttcaag tacttcctgc aaggcatggg ctacatggcc tcatcctgca tgactcgcct     1080

gtcccggtct cgtacagcct ctctgaccag tgcagcatcc gttgatggca accggtcccg     1140

ctctcgcacc ctgtcccaga gcagcgagtc tggaactctt tcttcggggc ccccggggca     1200

caccatggag gtctcctgtt gaatggccct tgttgcccta gagtgggacc cagccctcac     1260

ctcccccaga gctaacctgg gaggtgctga aggggcattg ggccaccgta agcaagggaa     1320

aaagggcaga tcatgcgggg agatgacctt gatctttgat tgctacccta accttgacct     1380

ttaacccgtg attcccccca gctcctggaa gagatgtcct aatatctctt agggacccag     1440

acccctaaat tctcctcctc ccccattttg atgttaaggt ggagagggca tatgcatcct     1500

ctgtcctgat ctaggtgtct atagctgagg ggtaagaggt tgttgtagtt gtcctggtgc     1560

ctccatcaga ctctccctac ttgtcccata tttgcaaggg gaggggattt ggggctgggg     1620

ctccattcac caaagctgag gtggcttctc attaaccctt taggactctg aagggtatgg     1680

acctacgtga atgtgtgtca gggggagact tgctggtggg ttagtggtcc tcaggatgtg     1740

atagaaacat ccagtgtaaa aaggaagttg gaatgggagt tggcgggcag tgaacgagtg     1800

tggggaagga ttggtgctgg ggcaacagga aggggcctgg ggccgtttgg ctgcactaac     1860

tttggtagct cagtgtgcat ctagagtggg actggggagg gagctaagct tgggctgggc     1920

tgcttggggc ttggcatagg gtggaaaggg ctaccctggg gctctgacca cactgtagta     1980

tgtgtggagg gtgccctccc gtctcccaca acttctgcta taacaataaa ctgtagagga     2040

atctgagtac cgttaaaaaa aaaaaaaaaa aaaaa                                2075


<210>  413
<211>  1652
<212>  DNA
<213>  homo sapiens

<400>  413
acggggcggg gtctggggcc cgccctcccg acacgtggcc ggggaccggg tatataaggc       60

ccttcggggc cggccaccct ttcactactt ctcccccgga ctccttggta gtctgttagt      120

gggagatcct tgttgccgtc ccttcgcctc cttcaccgcc gcagacccct tcaagttcta      180

gtcatgcgtg agtgcatctc catccacgtt ggccaggctg gtgtccagat tggcaatgcc      240

tgctgggagc tctactgcct ggaacacggc atccagcccg atggccagat gccaagtgac      300

aagaccattg ggggaggaga tgattccttc aacaccttct tcagtgaaac gggtgctggc      360

aagcatgtgc cccgggcagt gtttgtagac ttggaaccca cagtcattga tgaagttcgc      420

actggcactt accgccagct cttccaccct gagcaactca tcacaggcaa ggaagatgct      480

gccaataact atgcccgagg gcactacacc attggcaagg agatcattga cctcgtgttg      540

gaccgaattc gcaagctggc tgaccagtgc accggtcttc agggcttctt ggttttccac      600

agctttggtg ggggaactgg ttctgggttc acctcgctgc tcatggaacg tctctcagtt      660

gattatggca agaagtccaa gctggagttc tccatttacc cggcgcccca ggtttccaca      720

gctgtagttg agccctacaa ctccatcctc accacccaca ccaccctgga gcactctgat      780

tgtgccttca tggtagacaa tgaggccatc tatgacatct gtcgtagaaa cctcgatatc      840

gagcgcccaa cctacactaa ccttaaccgc cttattagcc agattgtgtc ctccatcact      900

gcttccctga gatttgatgg agccctgaat gttgacctga cagaattcca gaccaacctg      960

gtgccctacc cccgcatcca cttccctctg gccacatatg cccctgtcat ctctgctgag     1020

aaagcctacc acgaacagct tactgtagca gagatcacca atgcttgctt tgagccagcc     1080

aaccagatgg tgaaatgtga ccctcgccat ggtaaataca tggcttgctg cctgttatac     1140

cgtggtgacg tggttcccaa agatgtcaat gctgccattg ccaccatcaa aaccaagcgt     1200

accatccagt ttgtggattg gtgccccact ggcttcaagg ttggcattaa ttaccagcct     1260

cccactgtgg tgcctggcgg agacctggcc aaggtacaga gagctgtgtg catgctgagc     1320

aataccacag ctgttgccga ggcctgggct cgcctggacc acaagtttga cctgatgtat     1380

gccaagcgtg cctttgttca ctggtacgtg ggtgagggga tggaggaagg cgagttttca     1440

gaggcccgtg aggacatggc tgcccttgag aaggattatg aggaggttgg agcagatagt     1500

gctgacggag aggatgaggg tgaagagtat taacctgtgt gctgtacttt tacactcctt     1560

tgtcttggaa ctgtcttatt tttgttctgt aaatgtctat tgccgtaaat tgttaataaa     1620

attgaagttt ccattttaaa tgtcaaaaaa aa                                   1652


<210>  414
<211>  2535
<212>  DNA
<213>  homo sapiens

<400>  414
ttaaggccgc gctcgccagc ctcggcgggg cggctcccgc cgccgcaacc aatggatctc       60

ctcctctgtt taaatagact cgccgtgtca atcattttct tcttcgtcag cctcccttcc      120

accgccatat tgggccacta aaaaaagggg gctcgtcttt tcggggtgtt tttctccccc      180

tcccctgtcc ccgcttgctc acggctctgc gactccgacg ccggcaaggt ttggagagcg      240

gctgggttcg cgggacccgc gggcttgcac ccgcccagac tcggacgggc tttgccaccc      300

tctccgcttg cctggtcccc tctcctctcc gccctcccgc tcgccagtcc atttgatcag      360

cggagactcg gcggccgggc cggggcttcc ccgcagcccc tgcgcgctcc tagagctcgg      420

gccgtggctc gtcggggtct gtgtcttttg gctccgaggg cagtcgctgg gcttccgaga      480

ggggttcggg ctgcgtaggg gcgctttgtt ttgttcggtt ttgttttttt gagagtgcga      540

gagaggcggt cgtgcagacc cgggagaaag atgtcaaacg tgcgagtgtc taacgggagc      600

cctagcctgg agcggatgga cgccaggcag gcggagcacc ccaagccctc ggcctgcagg      660

aacctcttcg gcccggtgga ccacgaagag ttaacccggg acttggagaa gcactgcaga      720

gacatggaag aggcgagcca gcgcaagtgg aatttcgatt ttcagaatca caaaccccta      780

gagggcaagt acgagtggca agaggtggag aagggcagct tgcccgagtt ctactacaga      840

cccccgcggc cccccaaagg tgcctgcaag gtgccggcgc aggagagcca ggatgtcagc      900

gggagccgcc cggcggcgcc tttaattggg gctccggcta actctgagga cacgcatttg      960

gtggacccaa agactgatcc gtcggacagc cagacggggt tagcggagca atgcgcagga     1020

ataaggaagc gacctgcaac cgacgattct tctactcaaa acaaaagagc caacagaaca     1080

gaagaaaatg tttcagacgg ttccccaaat gccggttctg tggagcagac gcccaagaag     1140

cctggcctca gaagacgtca aacgtaaaca gctcgaatta agaatatgtt tccttgttta     1200

tcagatacat cactgcttga tgaagcaagg aagatataca tgaaaatttt aaaaatacat     1260

atcgctgact tcatggaatg gacatcctgt ataagcactg aaaaacaaca acacaataac     1320

actaaaattt taggcactct taaatgatct gcctctaaaa gcgttggatg tagcattatg     1380

caattaggtt tttccttatt tgcttcattg tactacctgt gtatatagtt tttacctttt     1440

atgtagcaca taaactttgg ggaagggagg gcagggtggg gctgaggaac tgacgtggag     1500

cggggtatga agagcttgct ttgatttaca gcaagtagat aaatatttga cttgcatgaa     1560

gagaagcaat tttggggaag ggtttgaatt gttttcttta aagatgtaat gtccctttca     1620

gagacagctg atacttcatt taaaaaaatc acaaaaattt gaacactggc taaagataat     1680

tgctatttat ttttacaaga agtttattct catttgggag atctggtgat ctcccaagct     1740

atctaaagtt tgttagatag ctgcatgtgg cttttttaaa aaagcaacag aaacctatcc     1800

tcactgccct ccccagtctc tcttaaagtt ggaatttacc agttaattac tcagcagaat     1860

ggtgatcact ccaggtagtt tggggcaaaa atccgaggtg cttgggagtt ttgaatgtta     1920

agaattgacc atctgctttt attaaatttg ttgacaaaat tttctcattt tcttttcact     1980

tcgggctgtg taaacacagt caaaataatt ctaaatccct cgatattttt aaagatctgt     2040

aagtaacttc acattaaaaa atgaaatatt ttttaattta aagcttactc tgtccattta     2100

tccacaggaa agtgttattt ttcaaggaag gttcatgtag agaaaagcac acttgtagga     2160

taagtgaaat ggatactaca tctttaaaca gtatttcatt gcctgtgtat ggaaaaacca     2220

tttgaagtgt acctgtgtac ataactctgt aaaaacactg aaaaattata ctaacttatt     2280

tatgttaaaa gatttttttt aatctagaca atatacaagc caaagtggca tgttttgtgc     2340

atttgtaaat gctgtgttgg gtagaatagg ttttcccctc ttttgttaaa taatatggct     2400

atgcttaaaa ggttgcatac tgagccaagt ataatttttt gtaatgtgtg aaaaagatgc     2460

caattattgt tacacattaa gtaatcaata aagaaaactt ccatagctat tcattgagtc     2520

aaaaaaaaaa aaaaa                                                      2535


<210>  415
<211>  1943
<212>  DNA
<213>  homo sapiens

<400>  415
agtgcgctgt gctcgagggg tgccggccag gcctgagcga gcgagctagc cagcaggcat       60

cgagggggcg cggctgccgt ccggacgaga caggcgaacc cgacgcagaa gagtccacca      120

ccggacagcc aggtagccgc cgcgtccctc gcacacgcag agtcgggcgg cgcggggtct      180

cccttgcgcc cggcctccgc cctctcctcc tctcctttcc ccttcttctc gctgtcctct      240

cctctctcgc tgcccgcgtt tgcgcagccc cgggccatgt ccgacgcgtc cctccgcagc      300

acatccacga tggagcgtct tgtcgcccgt gggaccttcc cagtactagt gcgcaccagc      360

gcctgccgca gcctcttcgg gccggtggac cacgaggagc tgagccgcga gctgcaggcc      420

cgcctggccg agctgaacgc cgaggaccag aaccgctggg attacgactt ccagcaggac      480

atgccgctgc ggggccctgg acgcctgcag tggaccgaag tggacagcga ctcggtgccc      540

gcgttctacc gcgagacggt gcaggtgggg cgctgccgcc tgctgctggc gccgcggccc      600

gtcgcggtcg cggtggctgt cagcccgccc ctcgagccgg ccgctgagtc cctcgacggc      660

ctcgaggagg cgccggagca gctgcctagt gtcccggtcc cggccccggc gtccaccccg      720

cccccagtcc cggtcctggc tccagccccg gccccggctc cggctccggt cgcggctccg      780

gtcgcggctc cggtcgcggt cgcggtcctg gccccggccc cggccccggc tccggctccg      840

gctccggccc cggctccagt cgcggccccg gccccagccc cggccccggc cccggccccg      900

gcccccgccc cggccccggc cccggacgcg gcgcctcaag agagcgccga gcagggcgcg      960

aaccaggggc agcgcggcca ggagcctctc gctgaccagc tgcactcggg gatttcggga     1020

cgtcccgcgg ccggcaccgc ggccgccagc gccaacggcg cggcgatcaa gaagctgtcc     1080

gggcctctga tctccgattt cttcgccaag cgcaagagat cagcgcctga gaagtcgtcg     1140

ggcgatgtcc ccgcgccgtg tccctctcca agcgccgccc ctggcgtggg ctcggtggag     1200

cagaccccgc gcaagaggct gcggtgagcc aatttagagc ccaaagagcc ccgagggaac     1260

ctgccggggc agcggacgtt ggaagggcgc tgggcctcgg ctgggaccgt tcatgtagca     1320

gcaaccggcg gcggctgccg cagagcagcg ttcggttttg tttttaaatt ttgaaaactg     1380

tgcaatgtat taataacgtc tttttatatc taaatgtatt ctgcacgaga aggtacactg     1440

gtcccaaggt gtaaagcttt aagagtcatt tatataaaat gtttaatctc tgctgaaact     1500

cagtgcaaaa aaaagaaaaa agaaaaaaaa aaggaaaaaa taaaaaaacc atgtatattt     1560

gtacaaaaag tttttaaagt tatactaact tatattttct atttatgtcc aggcgtggac     1620

cgctctgcca cgcactagct cggttattgg ttatgccaaa ggcactctcc atctcccaca     1680

tctggttatt gacaagtgta actttatttt catcgcggac tctggggaag ggggtcactc     1740

acaagctgta gctgccatac atgcccatct agcttgcagt ctcttcgcgc tttcgctgtc     1800

tctcttatta tgactgtgtt tatctgaaac ttgaagacaa gtctgttaaa atggttcctg     1860

agccgtctgt accactgccc cggcccctcg tccgccgggt tctaaataaa gaggccgaaa     1920

aatgctgcaa aaaaaaaaaa aaa                                             1943


<210>  416
<211>  1776
<212>  DNA
<213>  homo sapiens

<400>  416
agtgcgctgt gctcgagggg tgccggccag gcctgagcga gcgagctagc cagcaggcat       60

cgagggggcg cggctgccgt ccggacgaga caggcgaacc cgacgcagaa gagtccacca      120

ccggacagcc agcacatcca cgatggagcg tcttgtcgcc cgtgggacct tcccagtact      180

agtgcgcacc agcgcctgcc gcagcctctt cgggccggtg gaccacgagg agctgagccg      240

cgagctgcag gcccgcctgg ccgagctgaa cgccgaggac cagaaccgct gggattacga      300

cttccagcag gacatgccgc tgcggggccc tggacgcctg cagtggaccg aagtggacag      360

cgactcggtg cccgcgttct accgcgagac ggtgcaggtg gggcgctgcc gcctgctgct      420

ggcgccgcgg cccgtcgcgg tcgcggtggc tgtcagcccg cccctcgagc cggccgctga      480

gtccctcgac ggcctcgagg aggcgccgga gcagctgcct agtgtcccgg tcccggcccc      540

ggcgtccacc ccgcccccag tcccggtcct ggctccagcc ccggccccgg ctccggctcc      600

ggtcgcggct ccggtcgcgg ctccggtcgc ggtcgcggtc ctggccccgg ccccggcccc      660

ggctccggct ccggctccgg ccccggctcc agtcgcggcc ccggccccag ccccggcccc      720

ggccccggcc ccggcccccg ccccggcccc ggccccggac gcggcgcctc aagagagcgc      780

cgagcagggc gcgaaccagg ggcagcgcgg ccaggagcct ctcgctgacc agctgcactc      840

ggggatttcg ggacgtcccg cggccggcac cgcggccgcc agcgccaacg gcgcggcgat      900

caagaagctg tccgggcctc tgatctccga tttcttcgcc aagcgcaaga gatcagcgcc      960

tgagaagtcg tcgggcgatg tccccgcgcc gtgtccctct ccaagcgccg cccctggcgt     1020

gggctcggtg gagcagaccc cgcgcaagag gctgcggtga gccaatttag agcccaaaga     1080

gccccgaggg aacctgccgg ggcagcggac gttggaaggg cgctgggcct cggctgggac     1140

cgttcatgta gcagcaaccg gcggcggctg ccgcagagca gcgttcggtt ttgtttttaa     1200

attttgaaaa ctgtgcaatg tattaataac gtctttttat atctaaatgt attctgcacg     1260

agaaggtaca ctggtcccaa ggtgtaaagc tttaagagtc atttatataa aatgtttaat     1320

ctctgctgaa actcagtgca aaaaaaagaa aaaagaaaaa aaaaaggaaa aaataaaaaa     1380

accatgtata tttgtacaaa aagtttttaa agttatacta acttatattt tctatttatg     1440

tccaggcgtg gaccgctctg ccacgcacta gctcggttat tggttatgcc aaaggcactc     1500

tccatctccc acatctggtt attgacaagt gtaactttat tttcatcgcg gactctgggg     1560

aagggggtca ctcacaagct gtagctgcca tacatgccca tctagcttgc agtctcttcg     1620

cgctttcgct gtctctctta ttatgactgt gtttatctga aacttgaaga caagtctgtt     1680

aaaatggttc ctgagccgtc tgtaccactg ccccggcccc tcgtccgccg ggttctaaat     1740

aaagaggccg aaaaatgctg caaaaaaaaa aaaaaa                               1776


<210>  417
<211>  2122
<212>  DNA
<213>  homo sapiens

<400>  417
gcgagagttg cttttgcgcg cgaactgtaa gtgccagggt ctcagggtca ggtcgcggct       60

ggtcactgtg caggcgcttg ggtgacgcga cgatctcagc ggatctggtc accttcgtct      120

ccccgccatg gagacctcag cactcaagca gcaggagcag cccgcggcga ccaagatcag      180

gaacctgccc tgggttgaaa aataccggcc acagaccctg aatgatctca tttctcatca      240

ggacattctg agtaccattc agaagtttat caatgaagac cgactgccac acttgcttct      300

ctacggtccc ccagggacag gcaagacatc taccatccta gcctgtgcga aacagctata      360

taaagacaaa gaatttggct ccatggtctt ggagctgaat gcttcagatg accgaggaat      420

agacatcatt cgaggaccga tcctgagctt tgctagcaca aggacaatat ttaagaaagg      480

ctttaagcta gtgatcttgg atgaagcaga cgccatgact caggacgccc agaatgcctt      540

gagaagagta attgagaaat tcacagaaaa taccagattc tgcctcatct gtaactatct      600

gtcaaagatc atccctgcct tgcagtcccg ctgcacgagg tttcggttcg gtcccctgac      660

tcctgaactc atggttcccc gcctggaaca tgtcgtggaa gaagagaaag ttgatataag      720

tgaagatgga atgaaagcac tagtcactct ttccagtgga gacatgcgta gggctctgaa      780

cattttgcag agcaccaata tggcctttgg gaaggtgaca gaggagactg tctacacctg      840

caccgggcac ccgctcaagt cagacattgc caacatcctg gactggatgt tgaatcaaga      900

tttcaccaca gcctacagaa atattacaga gttgaaaact ctgaaggggt tggcactgca      960

tgatatcctg acagagatac acttgtttgt gcatagagtt gactttccat cttcagttcg     1020

aatacattta ttgaccaaaa tggcagacat tgagtacagg ctttctgttg gcaccaacga     1080

gaagatccag ctgagctccc tcattgctgc atttcaagtc accagagacc tgattgttgc     1140

agaggcctag atgctctgag ggccattcac aattctcagg gctcagcagt gatgggagaa     1200

cagaggacag ttccaggata aactgctgcc tggggctgtg ggatgaatca gtcaccccga     1260

atcttggaaa aacccccttc caggagagga tgggcaggca tttaaaaagt accatttttg     1320

tggttgtttg gagcagggat gtacaaaata attttaatgt attaactcat actgcctgtc     1380

ttttataggg gaaaaaaata acctttttta ttttaaagtt ataaggtttt taccttttag     1440

ttgcttggat gacagggaat tagcctaccc cattttggtc tggaacagaa gactttcaaa     1500

tttaatatgg tccaagtgtc ttcctactca aggtaaacat tatctccaaa attacattta     1560

tgattctaat atttggcatt gtgtctgtat ctaatttaaa cagatgttaa tggacgtctg     1620

gccgaaacta ttatactttt ataagatgag ctgaatcctc ttactttaaa aactggtctt     1680

tttatttacc ctctgtggta gaagagtcac cagcaggttc caaattgatg tgtatgatag     1740

gaaaaaaacc ttaattttaa atataatata gagccttaaa ctatgccact gggtggcaga     1800

ggctgtataa aacgcacttg ttttcatgca ggagcggggc aagtaaggtt gagcctgact     1860

gtaaacctag aactgcggaa ggactgggac ttttgtacaa atttcacatt tattttacag     1920

caatcatgct gcatttgtgt tagtgttctt tataataaaa aacaaagcag cctcctggct     1980

ggctgtgtta caagtgactc ttccttagac agctagaaag atgctgactt tgtcaaactt     2040

gcatttatat gaaaaccttc tgtctctaat atcacagaat aaactttctt tagatgctgt     2100

tctttataaa aaaaaaaaaa aa                                              2122


<210>  418
<211>  2032
<212>  DNA
<213>  homo sapiens

<400>  418
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtaatg     1560

ggactcctga ccaaccacgg tggggtacct catcagcccc agactgatta cgcgctctcc     1620

cctctcaccg ggggtctgga acctaccacc acggtgtcgg ccagctgcag tcagagacta     1680

gaccatatga agagcttgga cagtctgcca acatctcagt cctactgtcc acccacctat     1740

agcaccacag gctacagtat ggaccctgtc acaggctacc aatatgggca gtatggacaa     1800

agtaagcctt ggacttttta gggggcaatt tctcctggaa gggagataaa ctcaactctt     1860

ccttaagaaa ggtgaattag aggcaagatt aagccacaca tgccggtatc aatttttttt     1920

tttttttgca aagccagctg actgttccag caggggcttc cttgtgtaat tattttctta     1980

actgatgtca acaacatctt gcggttatta attgttgaga cgtgaaacct ga             2032


<210>  419
<211>  2512
<212>  DNA
<213>  homo sapiens

<400>  419
aattggtacc aggagagccc agaagccaca cacgcatctc tgcctctttg ctctggctct       60

cccaccctct tcccgtcttt ctctgcttcc ttgtcactgt tactccagga gacgttcact      120

tttcaccaac ctttctccaa gcatctccaa gccactgact atatatattt tgctacaaga      180

gacctagaag aggaaaaaag gcacgagact tttcaacaca tcgtttaaaa aaatcatcaa      240

cgaatttctt gcaatgtttg agaacaatta aaaggaaaaa gcgtttttta aaaaatctat      300

caactaagtg aacaatcatt catatcgtct acatcctgag atattattgt ccctcgctgc      360

ggacaccagc gagatgacag ctgctttttc atttttgaat gtaataaata tttgctgctt      420

ttaatatttt ccggaatctc ccctcgctat tccttggaat tttaactcta aagattggag      480

aacagattat caaaaaggct tttgcaagcc tccaaaatga tgctgagtcc ggaccaagca      540

gcagattcgg accatcccag ctcggcgcac tcggatccgg agtccctggg cggcacggac      600

accaaggtgc tcggcagcgt gtcggacctg gagccggtgg aggaggccga gggcgacggc      660

aagggcggca gccgagccgc gctctacccg cacccgcagc agctgagccg cgaggagaag      720

cgccgccgcc ggcgcgccac ggccaagtac cgctcggccc acgccacccg cgagcgcatc      780

cgcgtggaag ccttcaactt ggccttcgcc gagctccgca aattgctgcc cacgctgccc      840

ccggacaaga agctctccaa gatcgagatc ctgcgcctgg ccatctgcta catctcctat      900

ctcaaccacg tcctggacgt gtagggcggg gtgcgccgcg gggggccgcc tgtcccggcg      960

tccgcgaaac gctacggatc cggacgggcg ccgtcgctcg ggtggcggag gctgcggtgg     1020

cccagcgaga cggccgcctc gagagacggc cggggaagaa gctcgctacc tgttctctct     1080

ggtcagcagg gcgacgaggg aaggtttccg acgcaggcag gtggggttgt ctggcgagcc     1140

cgggggctcg caggggggat tttccaggcc aggagaacct cgtggagaca cccgagatga     1200

gccacttctg gggctcccca agggttgtgg ttttaaccca ctggagactt tgagttctcc     1260

tacattcatc cgccacaaat cttaatgtgt tgaaagaatg agggcagaag ttcagagtat     1320

gcaggctcat aactttaggc tatctggaat ttttctaatg gacaaatcac caaacactgg     1380

gaaggaggag agaggaggga tctctcccat agagatggaa ggcacagaaa ggtgcgactg     1440

gaaactttcc tttctgttgt gaaaataaag attatattag aatccaaata aaccctgaat     1500

atttagtaag tttaaaaaga caaattgaga acaagtagac acactgtggg aggatctgag     1560

cttggtgata ttttatcccc aagatatgac accaaggtag acaggaaaat ccatatttaa     1620

atggaaactt taatatctga ttacttttgc aggcgaagtg cccctttata tatccaaaaa     1680

catctatttg tgaccttaaa catgtggacc cataggtgca gttagaaaaa gacaacctat     1740

ttttatttat gttagaagga gtagagtatt tttttcaaga catttatttt tcagagtggt     1800

gatactttta ctttggatac tctgtgccaa tttatttata gtcaagtgtt tacacttttt     1860

cctgtggaat aattatgtct aactttttac gtgtttgttg agattatact gtggtctttc     1920

tttctgctct aattatattg cacttgtata acaaatttcc cacttctccc tgtttctaaa     1980

catattttat atattaagat gtttgttctt gaaaggttct tttgttgtga gatcagcaac     2040

actagcactt cactattata gttttttaaa aagtgtatta ttcttatctg tagttatgtc     2100

tgagaagtcc tttacaagct gtttataagg agagtagctt ctttgtgtgt gtgatgtttg     2160

tgcgtgtgat gaatttagca aattaagtta ttttcctaaa aaaaaaagaa aaaaagaatt     2220

cagaactact ttcctctgtg acaccaaaaa gaaaagtcta taacctgaaa atgtttcatg     2280

ttctctgctg tgaaactctt aaaacaagga gtgtatttta gagacaaggg aaaaaaacca     2340

catctgctat ccaaagattt tagtcttttt cagggttttt ttgtgtctct gttgctttat     2400

ataatgcaat attttgtagt gaaaatagat ataatctggt ttctatctga cgagtttttc     2460

atatctcatg aatggtgcgc tgttttgcat ataaataaag gtatcaaata aa             2512


<210>  420
<211>  1652
<212>  DNA
<213>  homo sapiens

<400>  420
aatcacggaa tcccggcggc cggcggcccg ggaggcagtc gcgcgctcgc atccccaaga       60

tggcggccgt taaggacagt tgtggcaaag gagaaatggc cacagggaat gggcggcggc      120

tccacctggg gattcctgag gccgtgtttg tggaagatgt agattccttc atgaaacagc      180

ctgggaatga gactgcagat acagtattaa agaagctgga tgaacagtac cagaagtata      240

agtttatgga actcaacctt gctcaaaaga aaagaaggct aaaaggtcag attcctgaaa      300

ttaaacagac tttggaaatt ctaaaataca tgcagaagaa aaaagagtcc accaactcaa      360

tggagaccag attcttgctg gcagataacc tgtattgcaa agcttcagtt cctcctaccg      420

ataaagtgtg tctgtggttg ggggctaatg taatgcttga atatgatatt gatgaagctc      480

aggcattgtt ggaaaagaat ttatcgactg ccacaaagaa tcttgattcc ctggaggaag      540

accttgactt tcttcgagat caatttacta ccacagaagt caatatggcc agggtttata      600

attgggatgt aaaaagaaga aacaaggatg actctaccaa gaacaaagca taatgctggc      660

aattaaaaat gtggtttagt tttccaaaca tgttatctta aatacccctt tatccttaca      720

ggttgacata actttgaatg ttttaacagc aagaatttta agaaaagata aacaccattt      780

tatttattta taaaaacaaa attagtttca aatatttttg acattgtgat ttttttttcc      840

acatttctca gcaaagctaa tggtatttta atcattattt ttgcctgtca taagaaaact      900

cttagctgaa atggccgaaa actgtgagac atgctatgga agctgaatgc cggacgctag      960

cacagtttac tttttccctt tctaattggc tgatgttact ctcacttgat gtggttaaac     1020

cattttagag gtagagaaga cagacagttt gaatatttgt aaacttgttt ttctttggta     1080

tatttaggac ttagtggtcc tctgttgcta ttgtcttcta taagtggagt ttcatgactt     1140

actgcttaac gaataactaa ctactatgat attctggaca ttttaggaaa tggtaatttg     1200

ccttgctaca cattaagagg gctattaaga ctacattttt tctaacctca gataagtgca     1260

gtgtctttgc aatgccaaca taagggagat cttggccaac gtgaaataaa attactcatt     1320

caaaactctg cctaaggtga ttttgtagtt cttaacagtt ctccagagca tcttgaacag     1380

gaatattaag ataaatgtga atctgcaatg gctgaaaaga gttgtgagct tttttattca     1440

tgataaaacc ttataggaat agtataaaaa atccctgtgg aaagctacta gtacattgac     1500

cagcgctggg tgatacagat tctgataaaa acataaatgt attagttcat ctccatgtag     1560

taaaaagtat acttatacaa tgttttgtac ttgtatttca tgaaattaaa acagtgatgc     1620

taaaactatg gcagagcact tttttcatgt ta                                   1652


<210>  421
<211>  2723
<212>  DNA
<213>  homo sapiens

<400>  421
gggcggggcg caggagcccc ggggcggagg agccggggag gcgggaggcg ggaggcggga       60

ggtgttgggg ccgttgaagc ggcctccctc ccgcccccag ccgcccggtc tggccccagc      120

cctgtcccga cccccggcct ggcccactcc gaccctaccc ggccgaaggg ttccgctgga      180

cacgcaggcg gcctccggag cagcccaagc ccatgagggc cgcgcgcccg gccgccggtg      240

ctgacgagac ggagctcctg gcccccgagg aggagcagag gatcaatgcg gttcaagaat      300

cgattccagc ggttcatgaa ccatcgagct ccagccaatg gccgctacaa gccaacttgc      360

tatgaacatg ctgctaactg ttacacacac gcattcctca ttgttccggc catcgtgggc      420

agtgccctcc tccatcggct gtctgatgac tgctgggaaa agataacagc atggatttat      480

ggaatgggac tctgtgccct cttcatcgtt tctacagtat ttcacattgt atcatggaaa      540

aagagccact taaggacagt ggagcattgt tttcacatgt gtgatagaat ggttatctat      600

ttcttcattg ctgcttctta tgctccatgg ttaaatcttc gtgaacttgg acccctggca      660

tctcatatgc gttggtttat ctggctcatg gcagctggag gaaccattta tgtatttctc      720

taccatgaaa aatataaggt ggttgaactc tttttctatc tcacaatggg attctctcca      780

gccttggtgg tgacatcaat gaacaacacc gatggacttc aggaacttgc ctgtgggggc      840

ttaatttatt gcttgggagt tgtgttcttc aagagtgatg gcatcattcc atttgcccac      900

gccatctggc acctgtttgt ggccacggca gctgcagtgc attactacgc catttggaaa      960

tacctttacc gaagtcctac ggactttatg cggcatttat gaccaatctg tactaattct     1020

ccaaaccagt attatttcaa ttatggcact tgggagtggg gtgagagcta aacattgcac     1080

agggaaagaa aaaaaataac tgcactgact ttatatcttt tgaatataat tactgtgaaa     1140

gtataaaggc tgtgttctgg aattttctgc ctcacagcaa ataaataagg tagtgaatta     1200

attattcatt ccattccact atcatgaagg actctgaata gacttggcca actgatgttt     1260

acaaaccaga cttttatatt ttaattttac agattttact acatgatttt tctaaattac     1320

tatgtcaggt tgtaaaagtc agtgcaataa caaaccttcc tttttaagaa gaaaattgtt     1380

tctattactt tcccattcac taggtaaaga atcatggaca gaacttacac tactttttac     1440

catgtttcat cttggcataa catggttctt ttttaaatag aaactttagt tttttgtaaa     1500

tttttaaaaa aatatttcat tgatatgcat ctctgcaggt cctcattcat gttgtaaatt     1560

tttgcagcaa gcagtcaaca ttccacaaac gaacaaacat tatacctctt ctgatagttt     1620

tattaagcat ggagaaattg ccaattttta aaaactgcag ttttccaaac ttttctgcca     1680

acctcttact ctgaattcag tgctgctttg ggacatatac ttgacctagc ttggtttacc     1740

agtgatggaa aagtattttg atatcattaa ctttttcaaa agatccaact ttttctctat     1800

gcctttgcca cattctcttc agggtctctt tccacagtgg ataaatgttt tttctgtatt     1860

atgacagtat tgttgtgatg gccatctgct ggaaactcct gaagagcatt atgtattaca     1920

gtgagcagtt gtattgcctg tttggtgccc aatggttaag tcattgtcac ttagctttat     1980

attgtcagtt tgatatttat tttaaattgt ggaactagat gcataaattc acatttctgc     2040

ctttcctttg catcttctca tatattgtgt tttttttttt ttttcctaga aaaaatattt     2100

aaagcattgt ttgacaggta gaaactcatg tatctgtagt ccatgagtta tatcctggct     2160

cagtggagtg atatttatgt attattttta cttttctctc agtgtcttat attaagatta     2220

acatgttgtt aatagttgct ttgttgatta atctctcttg ttggtgtttt aataaatgaa     2280

ataggcttgc ctttagatcg ggtgctgata ttgcctgttt cctagtaatg ggctgatcaa     2340

atgatcagtg gaattcttgg tttgatgata accttattaa ttgaaatttt ttactgatgt     2400

ggctttaaaa gaggtttatt ttgtatatgt ttagaactct ctgattttga tgaattatat     2460

gggaatgaga aacagaagaa gtggtatttg ctggcgagtt aaataggcaa ggtacccagt     2520

gataacacca accaaaccac tcctatctgc atgattctga acatctggat gcctgttgtt     2580

ttactgtgta tattttattt ttaatatatt aactttgtgg attcatttaa ggtctactca     2640

aaagtaacac tgtcaaaacc actaatatgt atgtaaaaat tgtgctgtat actacaataa     2700

agttgttact tggatttgtt cca                                             2723


<210>  422
<211>  751
<212>  DNA
<213>  homo sapiens

<400>  422
ccctgtctcc agtgggcgtc ttgggccccg gctctattct gggctgcggg cctgggaagg       60

gctcgccggg tgccaaatga gctgtcctaa ctctgcgggg ctgcagcttc ctgcatgatg      120

ctggggagct tggcgcctga cccaggatct agaaggcact ctgggcaggc cgcgctccgc      180

ccacgaaggt acccaaccct ctgggataga tgcaggaagc gatggttaag acccattttc      240

acccaacttc tcgccgcagg tctggcttac cacacgctcc tccccattcc cagtgagccg      300

ctttttgcag caccaggcga acacttacac cagtgctttg taaaggaatc ttattgtcca      360

ccccgtgtct tggcaaaaga acagtgatca cacagattcc tacttgggct ctttccttta      420

atcttcggag gctgagtttg cccaactcag gtttaaccac caaggactct gagagctggc      480

aggtctgagt aaccctggta acaattctct tcaccttatc aaaacctgag ctaaaaccaa      540

tgcatcagct gatgatgaca gcagagagtg gcagggctga ggacccaaag tcatttccca      600

ggctggcgga gaataaactg ccagggagaa gaatgagaag acaggagaca aactgtttgg      660

aaagctaaat cttccctctt aatgaataaa ggtttttgcc ttgtcttaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                                     751


<210>  423
<211>  2631
<212>  DNA
<213>  homo sapiens

<400>  423
caacagaaac caagcagcaa cagcccttgg aaagaggcta aatttttctt gacttctgca       60

gcaacaaaga ccgtgaaaag ttggcacttc tggcctaacg ctgccgtcat cctacccctc      120

accccagggc aacccaggct ggacatttag tgcctccctc tttattcctc tgtgatcatc      180

cagatcagca cttgactgtt tattttcaaa tctcacgaac ctcaccccaa gatcttcaca      240

ttctggatct cagctgctct tgaaggacag tgacttgtta ccaccgcaac agcagagcct      300

gccatcccca acagatcacc agttgtccct gacatcgtgc cctaccttgt ctccctttgt      360

ggtctcctaa atgcccatct cgttggcctt ggttcggcta gtggtatgga ggggtgctgc      420

ctagcactga cctgagagtg tgtgtgaccc actgacccaa tggacatcaa aggccagttc      480

tggaatgatg acgactcgga gggagataat gaatcagagg aatttctcta tggcgttcag      540

gggagctgtg cagctgacct gtatcgacac ccacagcttg atgcagacat tgaagccgtg      600

aaggagatct acagtgagaa ctctgtatcc atcagagaat atggaactat cgatgacgtg      660

gacattgacc tccacatcaa catcagcttc ctcgatgagg aagtctctac agcctggaag      720

gtcctccgga cagaacctat tgtgttgagg ctgcgatttt ctctctccca gtacctagat      780

ggaccagaac catccattga ggttttccag ccatcaaata aggaaggatt tgggctgggt      840

cttcagttga aaaagatcct gggtatgttt acatcccaac aatggaaaca tctgagcaat      900

gatttcttga agacccagca ggagaagagg cacagttggt tcaaggcaag tggtaccatc      960

aagaagttcc gagctggcct cagcatcttt tcacccatcc ccaagtctcc cagtttccct     1020

atcatacagg actccatgct gaaaggcaaa ctaggtgtac cagagcttcg ggttgggcgc     1080

ctcatgaacc gttccatctc ctgtaccatg aagaacccca aagtggaagt gtttggctac     1140

cctcccagcc cccaggcagg tctcctgtgc cctcagcacg tgggcctccc tcccccagca     1200

cggacctctc ctttggtcag tggtcactgc aagaacattc ccactctgga gtatggattc     1260

ctcgttcaga tcatgaagta tgcagaacag aggattccaa cattgaatga gtactgtgtg     1320

gtgtgtgatg agcagcatgt cttccaaaat ggatctatgc tgaagccagc tgtctgtact     1380

cgtgaactat gcgttttctc cttctacaca ctgggcgtca tgtctggagc tgcagaggag     1440

gtggccactg gagcagaggt ggtggatctg ctggtggcca tgtgtagggc agctttagag     1500

tcccctagaa agagcatcat ctttgagcct tatccctctg tggtggaccc cactgatccc     1560

aagactctgg cctttaaccc taagaagaag aattatgagc ggcttcagaa agctctggat     1620

agtgtgatgt ctattcggga gatgacccag ggctcatatt tggaaatcaa gaaacagatg     1680

gacaagttgg atcccctggc ccatcctctc ctgcagtgga tcatctctag caacaggtca     1740

cacattgtca aactacctct cagcaggctg aagttcatgc acacctcaca ccagttcctc     1800

ctgctgagca gccctcctgc caaggaggct cggttccgga ccgccaagaa gctctatggc     1860

agcacctttg ccttccatgg gtcccacatt gagaactggc attcgatcct gcgcaatggg     1920

ctggtcaatg catcctacac caaactgcag ctgcatggag cagcctatgg caaaggcatc     1980

tacctgagcc ccatctccag tatttccttt ggatactcag gaatgggaaa aggacagcac     2040

aggatgccct ccaaggatga gctggtccag agatacaaca ggatgaatac catcccccag     2100

acccgatcca ttcagtcacg gttcctgcag agtcggaatc taaactgtat agcactttgt     2160

gaagtgatta catctaagga cctccagaag catgggaaca tctgggtgtg ccctgtgtcc     2220

gaccatgtct gcacaagatt cttctttgta tatgaggatg gtcaggtggg cgatgccaac     2280

attaatactc aggaccccaa gatacagaag gaaatcatgc gtgtgatcgg aactcaggtt     2340

tacacaaact gagggggccc cagccctcgt accacccctg ttaccccagg atccatctgc     2400

cctcataaaa gtgttcaggt acagcagctg aggctgccct gaggaatcaa ggggccatta     2460

ccaaggggca ggaaaaggat atgtaagagg tggccttcat ggtagagctt gacccaagaa     2520

ctactccaca ttcggatggc ccagactgac tccatcccct gactttccct ttgacttcac     2580

cctgtttgta aataaaacaa taaaatggaa ggtgctgtgg actggaaaaa a              2631


<210>  424
<211>  2631
<212>  DNA
<213>  homo sapiens

<400>  424
caacagaaac caagcagcaa cagcccttgg aaagaggcta aatttttctt gacttctgca       60

gcaacaaaga ccgtgaaaag ttggcacttc tggcctaacg ctgccgtcat cctacccctc      120

accccagggc aacccaggct ggacatttag tgcctccctc tttattcctc tgtgatcatc      180

cagatcagca cttgactgtt tattttcaaa tctcacgaac ctcaccccaa gatcttcaca      240

ttctggatct cagctgctct tgaaggacag tgacttgtta ccaccgcaac agcagagcct      300

gccatcccca acagatcacc agttgtccct gacatcgtgc cctaccttgt ctccctttgt      360

ggtctcctaa atgcccatct cgttggcctt ggttcggcta gtggtatgga ggggtgctgc      420

ctagcactga cctgagagtg tgtgtgaccc actgacccaa tggacatcaa aggccagttc      480

tggaatgatg acgactcgga gggagataat gaatcagagg aatttctcta tggcgttcag      540

gggagctgtg cagctgacct gtatcgacac ccacagcttg atgcagacat tgaagccgtg      600

aaggagatct acagtgagaa ctctgtatcc atcagagaat atggaactat cgatgacgtg      660

gacattgacc tccacatcaa catcagcttc ctcgatgagg aagtctctac agcctggaag      720

gtcctccgga cagaacctat tgtgttgagg ctgcgatttt ctctctccca gtacctagat      780

ggaccagaac catccattga ggttttccag ccatcaaata aggaaggatt tgggctgggt      840

cttcagttga aaaagatcct gggtatgttt acatcccaac aatggaaaca tctgagcaat      900

gatttcttga agacccagca ggagaagagg cacagttggt tcaaggcaag tggtaccatc      960

aagaagttcc gagctggcct cagcatcttt tcacccatcc ccaagtctcc cagtttccct     1020

atcatacagg actccatgct gaaaggcaaa ctaggtgtac cagagcttcg ggttgggcgc     1080

ctcatgaacc gttccatctc ctgtaccatg aagaacccca aagtggaagt gtttggctac     1140

cctcccagcc cccaggcagg tctcctgtgc cctcagcacg tgggcctccc tcccccagca     1200

cggacctctc ctttggtcag tggtcactgc aagaacattc ccactctgga gtatggattc     1260

ctcgttcaga tcatgaagta tgcagaacag aggattccaa cattgaatga gtactgtgtg     1320

gtgtgtgatg agcagcatgt cttccaaaat ggatctatgc tgaagccagc tgtctgtact     1380

cgtgaactat gcgttttctc cttctacaca ctgggcgtca tgtctggagc tgcagaggag     1440

gtggccactg gagcagaggt ggtggatctg ctggtggcca tgtgtagggc agctttagag     1500

tcccctagaa agagcatcat ctttgagcct tatccctctg tggtggaccc cactgatccc     1560

aagactctgg cctttaaccc taagaagaag aattatgagc ggcttcagaa agctctggat     1620

agtgtgatgt ctattcggga gatgacccag ggctcatatt tggaaatcaa gaaacagatg     1680

gacaagttgg atcccctggc ccatcctctc ctgcagtgga tcatctctag caacaggtca     1740

cacattgtca aactacctct cagcaggctg aagttcatgc acacctcaca ccagttcctc     1800

ctgctgagca gccctcctgc caaggaggct cggttccgga ccgccaagaa gctctatggc     1860

agcacctttg ccttccatgg gtcccacatt gagaactggc attcgatcct gcgcaatggg     1920

ctggtcaatg catcctacac caaactgcag ctgcatggag cagcctatgg caaaggcatc     1980

tacctgagcc ccatctccag tatttccttt ggatactcag gaatgggaaa aggacagcac     2040

aggatgccct ccaaggatga gctggtccag agatacaaca ggatgaatac catcccccag     2100

acccgatcca ttcagtcacg gttcctgcag agtcggaatc taaactgtat agcactttgt     2160

gaagtgatta catctaagga cctccagaag catgggaaca tctgggtgtg ccctgtgtcc     2220

gaccatgtct gcacaagatt cttctttgta tatgaggatg gtcaggtggg cgatgccaac     2280

attaatactc aggaccccaa gatacagaag gaaatcatgc gtgtgatcgg aactcaggtt     2340

tacacaaact gagggggccc cagccctcgt accacccctg ttaccccagg atccatctgc     2400

cctcataaaa gtgttcaggt acagcagctg aggctgccct gaggaatcaa ggggccatta     2460

ccaaggggca ggaaaaggat atgtaagagg tggccttcat ggtagagctt gacccaagaa     2520

ctactccaca ttcggatggc ccagactgac tccatcccct gactttccct ttgacttcac     2580

cctgtttgta aataaaacaa taaaatggaa ggtgctgtgg actggaaaaa a              2631


<210>  425
<211>  3558
<212>  DNA
<213>  homo sapiens

<400>  425
ccgcggccgg gccgagccgc aggcgctgcc cgagccgcgg gcgctggagc ggctgtcggc       60

gcggtggcag gcgggagcca ggagtccggg gctcgggcgg gcggagcgca gcgcggggac      120

gcggcggagc gggccccgcg gctcggcggg ggccggcaga caggtgtgcc ggcggcgggc      180

ggctcgcgct caggcggctc caggccgggc ccggggtccg gagcggggag ccgggagccg      240

agcgaggacc cggcgcccgc agtccagtct tggccgcgcc cgtgctcggc ttggccgcgg      300

ggtgcgggga ccacggcccg gccgggccac ccgaagccta gtgctgggcc gggccgggcc      360

ggggtgggtg ggggcccgcc cggcccgccc atgggctcag gatgccggtg cggaggggcc      420

acgtcgcgcc gcagaacacc ttcctggaca ccatcatccg caagtttgag ggccagagcc      480

gtaagttcat catcgccaac gctcgggtgg agaactgcgc cgtcatctac tgcaacgacg      540

gcttctgcga gctgtgcggc tactcgcggg ccgaggtgat gcagcgaccc tgcacctgcg      600

acttcctgca cgggccgcgc acgcagcgcc gcgctgccgc gcagatcgcg caggcactgc      660

tgggcgccga ggagcgcaaa gtggaaatcg ccttctaccg gaaagatggg agctgcttcc      720

tatgtctggt ggatgtggtg cccgtgaaga acgaggatgg ggctgtcatc atgttcatcc      780

tcaatttcga ggtggtgatg gagaaggaca tggtggggtc cccggctcat gacaccaacc      840

accggggccc ccccaccagc tggctggccc caggccgcgc caagaccttc cgcctgaagc      900

tgcccgcgct gctggcgctg acggcccggg agtcgtcggt gcggtcgggc ggcgcgggcg      960

gcgcgggcgc cccgggggcc gtggtggtgg acgtggacct gacgcccgcg gcacccagca     1020

gcgagtcgct ggccctggac gaagtgacag ccatggacaa ccacgtggca gggctcgggc     1080

ccgcggagga gcggcgtgcg ctggtgggtc ccggctctcc gccccgcagc gcgcccggcc     1140

agctcccatc gccccgggcg cacagcctca accccgacgc ctcgggctcc agctgcagcc     1200

tggcccggac gcgctcccga gaaagctgcg ccagcgtgcg ccgcgcctcg tcggccgacg     1260

acatcgaggc catgcgcgcc ggggtgctgc ccccgccacc gcgccacgcc agcaccgggg     1320

ccatgcaccc actgcgcagc ggcttgctca actccacctc ggactccgac ctcgtgcgct     1380

accgcaccat tagcaagatt ccccaaatca ccctcaactt tgtggacctc aagggcgacc     1440

ccttcttggc ttcgcccacc agtgaccgtg agatcatagc acctaagata aaggagcgaa     1500

cccacaatgt cactgagaag gtcacccagg tcctgtccct gggcgccgac gtgctgcctg     1560

agtacaagct gcaggcaccg cgcatccacc gctggaccat cctgcattac agccccttca     1620

aggccgtgtg ggactggctc atcctgctgc tggtcatcta cacggctgtc ttcacaccct     1680

actcggctgc cttcctgctg aaggagacgg aagaaggccc gcctgctacc gagtgtggct     1740

acgcctgcca gccgctggct gtggtggacc tcatcgtgga catcatgttc attgtggaca     1800

tcctcatcaa cttccgcacc acctacgtca atgccaacga ggaggtggtc agccaccccg     1860

gccgcatcgc cgtccactac ttcaagggct ggttcctcat cgacatggtg gccgccatcc     1920

ccttcgacct gctcatcttc ggctctggct ctgaggagct gatcgggctg ctgaagactg     1980

cgcggctgct gcggctggtg cgcgtggcgc ggaagctgga tcgctactca gagtacggcg     2040

cggccgtgct gttcttgctc atgtgcacct ttgcgctcat cgcgcactgg ctagcctgca     2100

tctggtacgc catcggcaac atggagcagc cacacatgga ctcacgcatc ggctggctgc     2160

acaacctggg cgaccagata ggcaaaccct acaacagcag cggcctgggc ggcccctcca     2220

tcaaggacaa gtatgtgacg gcgctctact tcaccttcag cagcctcacc agtgtgggct     2280

tcggcaacgt ctctcccaac accaactcag agaagatctt ctccatctgc gtcatgctca     2340

ttggctccct catgtatgct agcatcttcg gcaacgtgtc ggccatcatc cagcggctgt     2400

actcgggcac agcccgctac cacacacaga tgctgcgggt gcgggagttc atccgcttcc     2460

accagatccc caatcccctg cgccagcgcc tcgaggagta cttccagcac gcctggtcct     2520

acaccaacgg catcgacatg aacgcggtgc tgaagggctt ccctgagtgc ctgcaggctg     2580

acatctgcct gcacctgaac cgctcactgc tgcagcactg caaacccttc cgaggggcca     2640

ccaagggctg ccttcgggcc ctggccatga agttcaagac cacacatgca ccgccagggg     2700

acacactggt gcatgctggg gacctgctca ccgccctgta cttcatctcc cggggctcca     2760

tcgagatcct gcggggcgac gtcgtcgtgg ccatcctggg tatggggtgg ggggcgggca     2820

ctggactgga aatgccctct gcagcctcaa gaggtgcgag ccttctgaat atgcagtcac     2880

tggggctgtg gacctgggac tgcctgcagg gtcactgggc tcctttaatt cacctaaact     2940

caggccctcc aagcggggcc atggagagga gccccacgtg gggtgaggct gctgaactct     3000

ggggttccca cattctcctt cccttcagga tccgccacaa acagacactt tttgcttcct     3060

taaagtagga tcaaatctag atcctctagc ctgggcagta gaggaagaaa tgctagcctg     3120

gaagctcggc atttggtttc actaagggcc atgtggttcc ctgcagcctc atgcctggcc     3180

ccttgacaca tccaaagcaa agggagtcct gccccctccc cccacttcct ttctaccctg     3240

cctgtgcaca gtgggtgggt tggtgtgtct ggacactgag gacttcctcc ccctttgcct     3300

gtccttccct cggccctgtg tgcctcaggg cagatatagc aagctctttc gaccatagtt     3360

gatggtagga cattttagac tttgtttctc agctctgtac aaacacaaat acacaccccc     3420

acaaaactaa aatcaaagtt tcactacata acactgggcc ttactgcatg tggttcattc     3480

tagcatttct gttctgtgct gtgctaagct atactactgt atgttctttc agtaaaaaaa     3540

aaaaaaaaaa aaaaaaaa                                                   3558


<210>  426
<211>  6419
<212>  DNA
<213>  homo sapiens

<400>  426
agtctgcggg cctccggggc agcggcgagg ccggagcgtc gcggcggaga ggacgagacc       60

gggacaagac cagggcagga gggagccggc cagccgcgag aaccccgcac gcccggcaag      120

atgctgtcct ggcggctgca gacgggcccc gagaaggccg agctccagga gctcaacgcc      180

cggctctatg actacgtgtg tcgggtgcgg gagctggagc gcgaaaacct actcctggag      240

gaggagctgc gcggccggcg cgggcgagag ggcctgtggg ccgaggggca ggcccgctgc      300

gccgaggagg cgcgcagctt gcggcagcag ctggacgagc tgagctgggc cactgcgctg      360

gcggagggcg agcgggacgc tctgcggcgc gagctgcggg agctgcagcg cctggatgcg      420

gaggagcgcg ccgcccgcgg ccgcctggac gccgagctgg gtgcgcagca gcgcgagctg      480

caggaggcgc tgggcgcgcg cgccgccctc gaggcgctgc tgggccggct gcaggccgag      540

cgccgaggcc tcgacgcggc ccacgaacgc gacgtgaggg agctgcgcgc gcgcgccgcc      600

agccttacca tgcatttccg cgcccgcgcc accggccccg ccgcgccgcc gccacgcctg      660

cgggaggtgc acgacagcta cgcactgctg gtggccgagt cgtggcggga gacggtgcag      720

ctgtacgagg acgaggtgcg cgagctggag gaggcgctgc ggcgcggcca ggagagcaga      780

ctccaggcgg aggaagagac gcggctgtgc gcgcaggagg cagaggcgct gcggcgcgag      840

gcgctcgggt tggagcagct gcgcgcgcgg ctggaggacg cgctgctgcg gatgcgcgag      900

gagtacggga tacaggccga ggagcggcag agagtgattg actgcctgga ggatgagaag      960

gcaaccctca ccttggccat ggctgactgg ctgcgggact atcaggacct cctgcaggtg     1020

aagaccggcc tcagtctgga ggtggcgacc taccgggcct tattggaagg agaaagtaat     1080

ccagagatag tgatctgggc tgagcacgtt gaaaacatgc cgtcagaatt cagaaacaaa     1140

tcctatcact ataccgactc actactacag agggaaaatg aaaggaatct attttcaagg     1200

cagaaagcac ctttggcaag tttcaatcac agctcggcac tgtattctaa cctgtcaggg     1260

caccgtggat ctcagacggg cacatctatt ggaggtgatg ccagaagagg cttcttgggc     1320

tcgggatatt cttcctcggc cactacccag caggaaaact catacggaaa agccgtcagc     1380

agtcaaacca acgtcagaac tttctctcca acctatggcc ttttaagaaa tactgaggct     1440

caagtgaaaa cattccctga cagaccaaaa gccggagata caagggaggt ccccgtttac     1500

ataggtgaag attccacaat tgcccgcgag tcgtaccggg atcgccgaga caaggtggca     1560

gcaggtgctt cggaaagcac acggtcaaat gagaggaccg tcattctggg aaagaaaaca     1620

gaagtgaaag ccacgaggga gcaagaaaga aacagaccag aaaccatccg aacaaagcca     1680

gaagagaaaa tgttcgattc taaagagaag gcttccgagg agagaaacct aagatgggaa     1740

gaattgacaa agttagataa ggaagcgaga cagagagaaa gccagcagat gaaggagaag     1800

gctaaggaga aggactcacc gaaggagaag agcgtgcgag agagagaggt gccgattagt     1860

ctagaagtat cccaggacag aagagcagag gtgtccccga aaggtttgca gacgcctgtg     1920

aaggatgctg gtggtgggac cggtagagag gcagaagcaa gagagctacg gttcaggttg     1980

ggcaccagtg atgccactgg ttctctgcaa ggcgattcca tgacagaaac cgtagcagaa     2040

aacatcgtta ccagtatcct gaagcagttc actcagtctc cagagacaga agcatctgct     2100

gattcttttc cagacacaaa agtcacttac gtggacagga aagagcttcc tggggaaagg     2160

aaaacaaaga ctgaaatagt tgtggagtct aaactgactg aggatgttga tgtttccgat     2220

gaagctggcc tggactacct tttaagcaag gatattaagg aagtggggct gaaaggcaag     2280

tcagccgagc agatgatagg agacatcatc aacctcggcc tgaaagggag ggaggggaga     2340

gcaaaggtcg tcaacgtgga gatcgtggag gagcccgtga gttatgtcag cggggagaag     2400

ccggaggagt tttccgtccc attcaaagtg gaggaggtcg aagatgtgtc gccaggcccc     2460

tgggggttgg ttaaggagga ggaaggttat ggagaaagcg atgtcacatt ctcagttaat     2520

cagcatcgaa ggaccaagca gcctcaggag aacacgactc acgtggaaga agtgacagag     2580

gcaggtgatt cagagggcga gcagagttat tttgtgtcca ctccagatga acaccccggg     2640

gggcacgaca gagatgacgg ctcggtgtac gggcagatcc acatcgagga ggaatccacc     2700

atcaggtact cttggcagga tgaaatcgtg caggggactc gaaggaggac acagaaggac     2760

ggtgcagtgg gcgagaaggt tgtgaagccc ttggatgtcc cagcgccctc tctggagggg     2820

gacctgggtt ccactcactg gaaagaacaa gctagaagcg gtgaatttca tgccgaaccc     2880

acagtcattg aaaaagaaat taaaataccc cacgaattcc acacctccat gaagggcatc     2940

tcctccaagg agccccggca gcagctggtg gaggtcatcg ggcagctgga ggaaaccctt     3000

cccgagcgca tgagggagga gctgtccgcc ctcaccagag aggggcaggg tgggccgggg     3060

agcgtttccg tggatgtcaa gaaggtccag ggtgctggtg gcagttccgt gaccctggtt     3120

gctgaagtca acgtctcaca aactgtggat gccgatcggt tagacctgga ggagctgagc     3180

aaagatgagg ccagtgagat ggagaaggct gtggagtcgg tggttcggga gagcctgagc     3240

aggcaacgca gcccagcgcc tggcagccca gatgaggaag gtggagcgga ggccccggct     3300

gctggcattc gctttaggcg ttgggccacc cgggagctgt acatcccttc aggcgagagc     3360

gaggttgctg gtggggcctc tcacagctcg ggacagcgca ctccccaggg cccagtgtcg     3420

gccactgtgg aggtcagcag ccccacaggc tttgcccagt cacaggtgct ggaggatgtg     3480

agccaggctg caaggcacat aaaactcggc ccctctgaag tctggaggac tgagcgaatg     3540

tcatatgaag gacccactgc agaagtggtg gagatggatg tgagtaacgt agaggcgatc     3600

cgcagccgga cacaggaagc gggagctctc ggtgtgtctg accgtggttc ctggagagac     3660

gcggacagta ggaatgacca ggcagttggt gtgagcttta aggcctctgc tggggaagga     3720

gaccaggccc acagagaaca gggcaaggag caggccatgt ttgataagaa ggtgcagctc     3780

cagagaatgg tagaccaaag gtcggtgatt tcagatgaaa agaaagttgc cctcctctat     3840

ctagacaatg aggaggagga gaatgatggg cattggtttt aataagcaga aacattttgt     3900

tttaatggca gcctgttggc gacgtgccaa catccaaagg ccttaactta ttttaagagg     3960

ccgagggagt ctatgaaaat ctcccctttt ttactttttt aaagagtact cccggcatgg     4020

tcaatttcct ttatagttaa tccgtaaagg tttccagtta attcatgcct taaaaggcac     4080

tgcaatttta tttttgagtt gggactttta caaaacactt ttttccctgg agtcttctct     4140

ccacttctgg agatgaattt ctatgttttg cacctggtca cagacatggc ttgcatctgt     4200

ttgaaactac aattaattat agatgtcaaa acattaacca gattaaagta atatatttaa     4260

gagtaaattt tgcttgcatg tgctaatatg aaataacaga ctaacatttt aggggaaaaa     4320

taaatacaat ttagactcta aaaagtcttt tcaaaaagaa atgggaaata ggcagactgt     4380

ttatgttaaa aaaattcttg ctaaatgatt tcatctttag gaaaaaatta cttgccatat     4440

agagctaaat tcatcttaag acttgaatga attgctttct atgtacagaa ctttaaacaa     4500

tatagtattt atggcgagga cagctgtagt ctgttgtgat atttcacatt ctatttgcac     4560

aggttccctg gcactggtag ggtagatgat tattgggaat cgcttacagt accatttcat     4620

tttttggcac taggtcatta agtagcacac agtctgaatg cccttttctg gagtggccag     4680

ttcctatcag actgtgcaga cttgcgcttc tctgcacctt atcccttagc acccaaacat     4740

ttaatttcac tggtgggagg tagaccttga agacaatgaa gagaatgccg atactcagac     4800

tgcagctgga ccggcaagct ggctgtgtac aggaaaattg gaagcacaca gtggactgtg     4860

cctcttaaag atgcctttcc caaccctcca ttcatgggat gcaggtcttt ctgagctcaa     4920

gggtgaaaga tgaatacaat aacaaccatg aacccacctc acggaagctt tttttgcact     4980

ttgaacagaa gtcattgcag ttggggtgtt ttgtccaggg aaacagttta ttaaatagaa     5040

ggatgttttg gggaaggaac tggatatctc tcctgcagcc cagcaccgag atacccagga     5100

cgggcctggg gggcgagaaa ggcccccatg ctcatgggcc gcggagtgtg gacctgtaga     5160

taggcaccac cgagtttaag atactgggat gagcatgctt cattggattc attttatttt     5220

acacgtcagt attgttttaa agtttctgtc tgtaaagtgt agcatcatat ataaaaagag     5280

tttcgctagc agcgcatttt ttttagttca ggctagcttc tttcacataa tgctgtctca     5340

gctgtatttc cagtaacaca gcatcatcgc actgactgtg gcgcactggg gaataacagt     5400

ctgagctagc accaccctca gccaggctac aacgacagca ctggagggtc ttccctctca     5460

gattcacctg gaggccctca gacccccagg gtgcacgtct ccccaggtcc tgggagtggc     5520

taccgcaggt agtttctgga gagcacgttt tcttcattga taagtggagg agaaatgcag     5580

cacagctttc aagatactat tttaaaaaca ccatgaatca gatagggaaa gaaagttgat     5640

tggaatagca agtttaaacc tttgttgtcc atctgccaaa tgaactagtg attgtcagac     5700

tggtatggag gtgactgctt tgtaaggttt tgtcgtttct aatacagaca gagatgtgct     5760

gattttgttt tagctgtaac aggtaatggt ttttggatag atgattgact ggtgagaatt     5820

tggtcaaggt gacagcctcc tgtctgatga caggacagac tggtggtgag gagtctaagt     5880

gggctcagtt tgatgtcagt gtctgggctc atgacttgta aatggaagct gatgtgaaca     5940

ggtaattaat attatgaccc acttctattt actttgggaa atatcttgga tcttaattat     6000

catctgcaag tttcaagaag tattctgcca aaagtattta caagtatgga ctcatgagct     6060

attgttggtt gctaaatgtg aatcacgcgg gagtgagtgt gcccttcaca ctgtgacatt     6120

gtgacattgt gacaagctcc atgtccttta aaatcagtca ctctgcacac aagagaaatc     6180

aacttcgtgg ttggatgggg ccggaacaca accagtcttt ttgtatttat tgttactgag     6240

acaaaacagt actcactgag tgtttttcag tttcctactg gtggttttga tattgtttgt     6300

ttaagatgta tatttagaat gacatcatct aagaagctga ttttgctaaa ctcctgttcc     6360

ctacaatggg aaatgtcaca agaatgtgca aaaataaaaa tctgaggaaa aaacccaca      6419


<210>  427
<211>  6046
<212>  DNA
<213>  homo sapiens

<400>  427
gggtggcggg gggttgcaag tgggaagcct gctgttcagc tgccggggct ctccgcctcc       60

ccccacctgt atgaggctgg gtctggggaa cctgtgctca gcattccacc ccctggagct      120

tgggcttggt cttccctgcg ggtccctgcg ctgacattca ggcggggagc caggaggcct      180

ggcgcgcctc cagagcccgc cgggggagcc gggcgagggt tctgggctct gacggcgggg      240

tcgcagggtc gcccgcctcc tggacacgtc tgtaggccta gggaagcctg ccggccggga      300

ggtacagagt aggagaagcc agatcccagg gcggacaacg agaagtcgtc aggctaagaa      360

atggcatttc aaaaggcagt gaaagggacg attcttgttg gaggaggtgc tcttgcaact      420

gttttaggac tttctcagtt tgctcattac agaaggaaac aaatgaacct ggcctatgtt      480

aaagcagcag actgcatttc agaaccagtt aacagggagc ctccttccag agaagctcag      540

ctactgactt tgcaaaacac atctgaattt gatatccttg ttattggagg aggagcaaca      600

ggaagtggct gtgcgctaga tgctgtcacc agaggactaa aaacagccct tgtagaaaga      660

gatgatttct catcagggac cagcagcaga agcactaaat tgatccatgg tggtgtgaga      720

tatctgcaga aggccatcat gaagttggat attgagcagt ataggatggt aaaagaagcc      780

cttcatgagc gtgccaacct gctagaaatt gctccccatt tatcagctcc attgcctata      840

atgcttccag tttacaagtg gtggcagtta ccttactact gggtaggaat caagctgtat      900

gatttggttg caggaagcaa ttgcctaaaa agcagttatg tcctcagcaa atcaagagcc      960

cttgaacatt tcccaatgct ccagaaggac aaactggtag gagcaattgt ctactatgac     1020

ggacaacata acgatgcacg gatgaacctt gccattgctc tgactgctgc caggtatggg     1080

gctgccacag ccaattacat ggaggtagtg agcttgctca agaagacaga cccccagaca     1140

gggaaagtgc gtgtgagcgg cgcacggtgc aaggatgtcc tcacagggca ggaatttgac     1200

gtgagagcca aatgtgttat caatgccacg ggacctttca cggactctgt gcgcaaaatg     1260

gatgataaag acgcagcagc tatctgccag ccaagtgctg gtgtccatat tgtgatgcct     1320

ggttattaca gcccagagag catgggactt cttgacccag cgaccagtga tgggcgagtt     1380

attttcttct taccctggca aaagatgacg atcgctggca ctactgatac tccaactgat     1440

gttacacacc atccaattcc ttcagaagaa gatatcaact tcattttgaa tgaagtgcgt     1500

aattacctga gttgtgatgt tgaagtgaga agaggggatg tcctggcagc atggagtgga     1560

atccgtcctc ttgttacaga ccccaaatct gcagatactc agtctatctc ccgaaatcat     1620

gttgttgata tcagtgagag tggccttatt actatagcag gtggaaagtg gacaacttat     1680

cggtctatgg cagaagatac cataaatgct gctgtcaaaa ctcataattt aaaagcagga     1740

ccaagtagaa cagttgggct tttccttcaa gggggtaaag attggagccc cacactctac     1800

attaggcttg tgcaggatta tggacttgaa agcgaggtgg cacagcatct tgccgccacc     1860

tatggtgata aggcctttga ggtggccaaa atggcaagtg tgactggcaa aaggtggcct     1920

attgttggag tacgtcttgt gtcagaattt ccatatattg aagcagaggt gaaatatggg     1980

attaaggagt atgcctgcac tgctgtggat atgatttcac gtcgtactcg cctggccttt     2040

ctaaatgtcc aggcagcaga ggaagcccta cccaggattg ttgaactgat gggcagggaa     2100

ctgaattggg atgattataa gaagcaggaa caacttgaaa cagccaggaa gtttctatat     2160

tatgaaatgg gctataaatc tcgatcagaa cagttaacag atcgctctga aattagccta     2220

ctgccttcag acattgacag gtataagaag agatttcata agtttgatgc agaccagaaa     2280

ggctttatta ccattgttga tgttcagcgt gtattagaga gtatcaatgt ccaaatggat     2340

gaaaatacac tccatgaaat tctaaatgaa gttgatttga ataaaaatgg acaggttgaa     2400

ctcaatgaat ttttgcagct gatgagtgct attcaaaaag gaagggtatc tggaagccgg     2460

cttgctatac taatgaaaac tgcagaagag aacctcgaca gaagagttcc aattccagtg     2520

gaccgtagtt gtggaggatt gtgagtctgg gcagtaaatc cacagccaac aaacatagaa     2580

acgacaaatc accatgtaac aaccagagat gactgaaacc actctgaaat aatgaatgtg     2640

gatagctgcc ttttttaaca ctagaaaaca ttccaaaact ttaaggtgtt ggtgtatttg     2700

ccagctttat ttgctgtact ttatttgtat ttgccattca gtctagcttt taagtatatt     2760

tttttctttt tctcattttc aatgcacatt agttttgcat ctgttttgtg acctgttaga     2820

tgtgacacat tctctttttg tttattccct tattctaaat gagttctaaa aacataatat     2880

tttggcaaaa attgaaaaaa gctggagaca ttttgtgaca tgcatacaga tagcatgtgt     2940

tattaaaaag agttgcctat tgaaatgatc gtgtttctgg agaaattaag cttatagaca     3000

gcatgtgtta ttaaaaagag ttacctattg aaatgatagt gtttctggag atttctcagc     3060

cccatcttcc tccagcttgt ctaccttcct catgcaaaca atattccaca tttttatatc     3120

tagagcatga ctggctaact ggagagggaa ggaaaagttt agatctggtt actggagcaa     3180

gtctcaaaga gaaactctga aagcttccag aatcacaggt ataagataag gatagcattg     3240

acatttgctg ggagttacag tgatagtttc atctcagcag ttcatttttt tcttcagtca     3300

ctgctggttt tctttgacta ttatagttgc caggaagatc cttgctcttc ttactttaaa     3360

accagcattt aagtggcaat ttggatgtaa taggatgaga ccaaatttat ctaattatta     3420

cagtagtaat acatttaaga gttaaaaatg tgtttttata tatccacata tgataacaaa     3480

agattcaatt cccaagccta aattttgaag catgtggtat tgtcaaatct agcttaccat     3540

cttttttggg ggtacttgca accatagtaa aggaagatgg aatagacttt agttaacttt     3600

aattataatt atatgttaaa taaggcacat aaccagtttc caaggtcatc atggttgctt     3660

aaagtctttc cccttctgta ctccatggaa atattctcag taaaccaaaa acaaaaatgg     3720

aaaaataatc accaaccccc atcccgacac acacacagag tccaaagcaa aagtcagtgt     3780

gtattgaatt taacaagtaa tgcagtttgg gatgcttttg ctacattttg gtggcatttt     3840

aactagttat ctgaatattt attaatcgta cttcctcttg taaagttaac tacttacttt     3900

tttgttgttg tttttttaac atcaggttct gtatctaata ggagatgtaa cactttattt     3960

catggcaggt ttttattgca gagacttgaa gtcttagttt tttaaactgg cacataaaac     4020

actttttgct gttattttta tttatgtcaa tactgcagag tatctttatg ccttattcaa     4080

gtggattctg agcctgtatg tcacaatgta aacactggag gttcactcac ctacgcactc     4140

acccaccacc tctgaaagaa acagaaactg cagagaaaga cagcatctta gctcattttg     4200

tttttaaatg aggttttaga cgcttgccac ttcctaaggg aaatcctaaa acagagcaag     4260

tgatgctccc aggtatcact gtgaactttt ttctttcaaa gtgtgaattt ttacactggc     4320

tttttcattt ttttaaagta attgaagctt gtggctttac aacttagtgt tttttgctat     4380

ccagataaca agtttcattg tttagaaccc agtgacactt aataggtaga taaattgtcc     4440

tttaaaatat cccagatgat atacacaata tggtacattt gtgctctctc tctctgtttt     4500

tctctctttc tctttctagt tagatcaaga taacgatgac ttgtaccctc cctgattctg     4560

ttacagtagg gcccgggcag atctgtgttt gttaaacagg ccttgtttgt gcatgctttg     4620

ctatgaatga agttccttta aggacaaaga aaagcacact tttcttcttt tgagcatatc     4680

tgcttttact ttaaatctgc taatttctaa aatgtagagt ccttcaccaa tcccagagac     4740

tcaatttgga aatgaactga tttcaagccg ttactgtgaa taaagcaccc cagcattttg     4800

tataagctct taattaaacc tgtacagctt ctttacctga tttaagaaag ggagacaagc     4860

aatagggggg aataagcttc ttcaaaattc attccaagca caaaagaaat tttttccctt     4920

tgcatataaa cttgacatca gttgattctg ttggggtcgg ggtgggtatg cagggattgc     4980

cttttattat caagtgattt atttcaagag cctttgaggg gattcaggtg aaggaacccc     5040

catctgtgct ggagagttgg atactccttt aaatagcccc caccacagtc ataacaataa     5100

tgataatgct ggattatttg ttaagccaag gttgtctgcc tcatatccat catgctgttt     5160

gcaatattct tgctttcaat caatttatac tgagtgtaac tttaggattt ctgctattaa     5220

atgcatgctc tctatcctgc ttcagtttct ggctttgctt tgtctgtttc aaaatatgta     5280

gcttcctctt ttgtacaaca aaaaactcat tctcactttt actaaatata ctgtaggagt     5340

catcattgat gttatttttc tcttatgtat ctgtaaagat ttttggcata tgaatgtaat     5400

attaaagtca atgatgctat aacttgcgat gtttgcatca tgtcaacctt tttgaaggag     5460

tgaaaaagcc ctactatgtt tttaaatagc aagtgtaagc tcagtgctag agtggatata     5520

cacaccgcat gttttcatat gtggcacttt tatgtatcat gttgggttat tgttctagac     5580

tggactgtta aatactatgt ttgaggctgg gttgtcattt ttataactgt cttggtgttt     5640

tatggccatt atttattact tttgatacac agaatgagct gcatgcattt atagagcaat     5700

aagaggatgt atttaatgtg ccttgttttt aactgaataa gaactggaag catgaatcaa     5760

taaaactgat taaaatggtc tatttgctag cattttgatg ttacttgcag tcagataact     5820

ttgattactg ttgaagttta aaaaaagttt gaaaatattt ttacaaactg tgtttttgat     5880

gacacaaaag tgaaatatct acagagatag atgtaatttt ataagactgc cagaattatt     5940

tgtattaatt tgttgctgta gcctttaggg catgacttct gtatttgtgc aatcctattc     6000

tacaattaca ttcatcctat tacaactcaa aaaaaaaaaa aaaaaa                    6046


<210>  428
<211>  5063
<212>  DNA
<213>  homo sapiens

<400>  428
gccttagaaa agttaacgag aaccagatgt ggtggccact gccgaacttt ctcagagccg       60

gtgattggtc cccagccgag ggcctcagcc aattagcttg ctgggtgggc ctggagtccc      120

gccccgccca ggcgcccgcg gagatccagg ttcgaggctg gcgcggcgcg gagagtgggc      180

tggaggccgg ggcgggacgc gttgtgcagc gggtaagcgc acggccgagc gagcatggag      240

ggggaccggg tggccgggcg gccggtgctg tcgtcgttac cagtgctact gctgctgccg      300

ttgctaatgt tgcgggccgc ggcgctgcac ccagacgagc tcttcccaca cggggagtcg      360

tggggggacc agctcctgca ggaaggcgac gacgaaagct cagccgtggt gaagctggcg      420

aatcccctgc acttctacga agcccgattc agcaacctct acgtgggcac caacggcatc      480

atctccactc aggacttccc cagggaaacg cagtatgtgg actatgattt ccccaccgac      540

ttcccggcca tcgccccttt tctggcggac atcgacacga gccacggcag aggccgagtc      600

ctgtaccgag aggacacctc ccccgcagtg ctgggcctgg ccgcccgcta tgtgcgcgct      660

ggcttcccgc gctctgcgcg ctttaccccc acccacgcct tcctggccac ctgggagcag      720

gtaggcgctt acgaggaggt caagcgcggg gcgctgccct cgggagagct gaacactttc      780

caggcagttt tggcatctga tgggtctgat agctacgccc tctttcttta tcctgccaac      840

ggcctgcagt tccttggaac ccgccccaaa gagtcttaca atgtccagct tcagcttcca      900

gctcgggtgg gcttctgccg aggggaggct gatgatctga agtcagaagg accatatttc      960

agcttgacta gcactgaaca gtctgtgaaa aatctctatc aactaagcaa cctggggatc     1020

cctggagtgt gggctttcca tatcggcagc acttccccgt tggacaatgt caggccagct     1080

gcagttggag acctttccgc tgcccactct tctgttcccc tgggacgttc cttcagccat     1140

gctacagccc tggaaagtga ctataatgag gacaatttgg attactatga tgtgaatgag     1200

gaggaagctg aataccttcc gggtgaacca gaggaggcat tgaatggcca cagcagcatt     1260

gatgtttcct tccaatccaa agtggataca aagcctttag aggaatcttc caccttggat     1320

cctcacacca aagaaggaac atctctggga gaggtagggg gcccagattt aaaaggccaa     1380

gttgagccct gggatgagag agagaccaga agcccagctc caccagaggt agacagagat     1440

tcactggctc cttcctggga aaccccacca ccgtaccccg aaaacggaag catccagccc     1500

tacccagatg gagggccagt gccttcggaa atggatgttc ccccagctca tcctgaagaa     1560

gaaattgttc ttcgaagtta ccctgcttca ggtcacacta cacccttaag tcgagggacg     1620

tatgaggtgg gactggaaga caacataggt tccaacaccg aggtcttcac gtataatgct     1680

gccaacaagg aaacctgtga acacaaccac agacaatgct cccggcatgc cttctgcacg     1740

gactatgcca ctggcttctg ctgccactgc caatccaagt tttatggaaa tgggaagcac     1800

tgtctgcctg aaggggcacc tcaccgagtg aatgggaaag tgagtggcca cctccacgtg     1860

ggccatacac ccgtgcactt cactgatgtg gacctgcatg cgtatatcgt gggcaatgat     1920

ggcagagcct acacggccat cagccacatc ccacagccag cagcccaggc cctcctcccc     1980

ctcacaccaa ttggaggcct gtttggctgg ctctttgctt tagaaaaacc tggctctgag     2040

aacggcttca gcctcgcagg tgctgccttt acccatgaca tggaagttac attctacccg     2100

ggagaggaga cggttcgtat cactcaaact gctgagggac ttgacccaga gaactacctg     2160

agcattaaga ccaacattca aggccaggtg ccttacgtct cagcaaattt cacagcccac     2220

atctctccct acaaggagct gtaccactac tccgactcca ctgtgacctc tacaagttcc     2280

agagactact ctctgacttt tggtgcaatc aaccaaacat ggtcctaccg catccaccag     2340

aacatcactt accaggtgtg caggcacgcc cccagacacc cgtccttccc caccacccag     2400

cagctgaacg tggaccgggt ctttgccttg tataatgacg aagaaagagt gcttagattt     2460

gctgtgacca atcaaattgg cccggtcaaa gaggattcag accccactcc ggggaatcct     2520

tgctatgatg ggagccacat gtgtgacaca acagcacggt gccatccagg gacaggtgta     2580

gattacacct gtgagtgcgc atctgggtac cagggagatg gacggaactg tgtggatgaa     2640

aatgaatgtg caactggctt tcatcgctgt ggccccaact ctgtatgtat caacttgcct     2700

ggaagctaca ggtgtgagtg ccggagtggt tatgagtttg cagatgaccg gcatacttgc     2760

atcttgatca ccccacctgc caacccctgt gaggatggca gtcatacctg tgctcctgct     2820

gggcaggccc ggtgtgttca ccatggaggc agcacgttca gctgtgcctg cctgcctggt     2880

tatgccggcg atgggcacca gtgcactgat gtagatgaat gctcagaaaa cagatgtcac     2940

cctgcagcta cctgctacaa tactcctggt tccttctcct gccgttgtca acccggatat     3000

tatggggatg gatttcagtg catacctgac tccacctcaa gcctgacacc ctgtgaacaa     3060

cagcagcgcc atgcccaggc ccagtatgcc taccctgggg cccggttcca catcccccaa     3120

tgcgacgagc agggcaactt cctgccccta cagtgtcatg gcagcactgg tttctgctgg     3180

tgcgtggacc ctgatggtca tgaagttcct ggtacccaga ctccacctgg ctccaccccg     3240

cctcactgtg gaccatcacc agagcccacc cagaggcccc cgaccatctg tgagcgctgg     3300

agggaaaacc tgctggagca ctacggtggc accccccggg atgaccagta cgtgccccag     3360

tgcgatgacc tgggccactt catccccctg cagtgccacg gaaagagcga cttctgctgg     3420

tgtgtggaca aagatggcag agaggtgcag ggcacccgct cccagccagg caccacccct     3480

gcgtgtatac ccaccgtcgc tccacccatg gtccggccca cgccccggcc agatgtgacc     3540

cctccatctg tgggcacctt cctgctctat actcagggcc agcagattgg ctacttaccc     3600

ctcaatggca ccaggcttca gaaggatgca gctaagaccc tgctgtctct gcatggctcc     3660

ataatcgtgg gaattgatta cgactgccgg gagaggatgg tgtactggac agatgttgct     3720

ggacggacaa tcagccgtgc tggtctggaa ctgggagcag agcctgagac gatcgtgaat     3780

tcaggtctga taagccctga aggacttgcc atagaccaca tccgcagaac aatgtactgg     3840

acggacagtg tcctggataa gatagagagc gccctgctgg atggctctga gcgcaaggtc     3900

ctcttctaca cagatctggt gaatccccgt gccatcgctg tggatccaat ccgaggcaac     3960

ttgtactgga cagactggaa tagagaagct cctaaaattg aaacgtcatc tttagatgga     4020

gaaaacagaa gaattctgat caatacagac attggattgc ccaatggctt aacctttgac     4080

cctttctcta aactgctctg ctgggcagat gcaggaacca aaaaactgga gtgtacacta     4140

cctgatggaa ctggacggcg tgtcattcaa aacaacctca agtacccctt cagcatcgta     4200

agctatgcag atcacttcta ccacacagac tggaggaggg atggtgttgt atcagtaaat     4260

aaacatagtg gccagtttac tgatgagtat ctcccagaac aacgatctca cctctacggg     4320

ataactgcag tctaccccta ctgcccaaca ggaagaaagt aagtacagta atgtaaagga     4380

agacttggag tttacaatca gaacctggac cctaaagaac agtgactgca aaggcaaaga     4440

aagtaaaaaa ggaattggcc attagacgtt cctgagcatc caagatgaac attttgtagt     4500

gcaaaaagac ttttgtgaaa agctgatacc tcaatcttta ctactgtatt tttaaaaatg     4560

aaggttgtta ttgcaagttt aaaaaggtaa cagaatttta actgttgctt attaaagcaa     4620

cttcttgtaa acatttatca ttaatattta aaagatcaaa ttcattcaac taagaattag     4680

agtttaagac tctaaacctg atttttgcca tggattcctt ctggccaaga aattaaagca     4740

catgtgatca atataacaat ataatcctaa accttgacag ttggagaagc caatgcagaa     4800

ctgatgggaa aggaccaatt atttatagtt tcccaacaaa agttctaaga ttttttacct     4860

ctgcatcagt gcatttctat ttatatcaaa aggtgctaaa atgattcaat ttgcattttc     4920

tgatcctgta gtgcctctat agaagtaccc acagaaagta aagtatcaca tttataaata     4980

ccaaagatgt aacaatttta aaattttcta gattactcca ataaagtgtt ttaagttttc     5040

ctatgaaaaa aaaaaaaaaa aaa                                             5063


<210>  429
<211>  14100
<212>  DNA
<213>  homo sapiens

<400>  429
ggcgcggtac aggagcagca ctgccggcgg gggcgggtgc cagggacttg gaggtggagg       60

ggacgcggcg gtactctggc gtcttccgac ttcgactcct taccttaaaa gatgctggag      120

tcatatgtaa ctccaatttt aatgagctat gtgaatcgct acatcaagaa cttaaagccg      180

tcggatctac agctttcact atggggtgga gacgtggtac tcagcaagct cgagttaaag      240

ttggatgtgc tggaacagga actgaaatta ccattcactt ttttaagtgg acatattcat      300

gaattgagga ttcatgtacc atggacaaaa ctgggttcag aaccagtggt aattaccatc      360

aatactatgg aatgcatttt gaaacttaag gatgggatac aggatgacca tgaaagctgt      420

ggttctaatt ctaccaaccg tagtactgct gagagcacaa aatcatcaat caaaccgcgg      480

agaatgcagc aggctgctcc tacagatcct gacttaccac caggttatgt gcagagtctg      540

attagacgag ttgtaaataa tgtaaacatt gtgataaata atctcatact aaaatatgtt      600

gaagatgata tcgtcctttc cgtcaatatc acttctgcag aatgttatac agtaggtgaa      660

ttatgggatc gtgcattcat ggatatttct gcaactgatt tggtgctgag aaaggttatc      720

aatttttctg actgtacagt ttgtcttgat aaacggaatg ccagtggtaa aatagaattt      780

taccaggatc ctttattata caaatgttcc ttcagaactc gtcttcattt tacatatgaa      840

aacctaaatt ccaagatgcc atctgttatt aaaattcata ctttagtgga aagtttgaaa      900

ctttctatca cagatcaaca actgcctatg tttattcgta taatgcaact tggaattgct      960

ctttactatg gagaaatagg caattttaaa gaaggcgaaa tagaggacct tacttgtcat     1020

aataaagata tgctaggaaa cattacaggt tctgaagatg aaacaagaat agatatgcaa     1080

tatcctgctc agcataaagg tcaagagtta tattcacagc aagatgagga gcagccacag     1140

ggatgggtgt catgggcctg gtcctttgtg cctgcaattg tgagttatga cgatggcgag     1200

gaagactttg ttgggaacga tcctgcatca accatgcatc aacaaaaagc acagactttg     1260

aaggatccta ttgtttctat aggattttat tgcacaaagg caacggtgac tttcaaactc     1320

acagaaatgc aagttgagag tagttattac agtccacaga aagtaaaatc taaagaagta     1380

ttgtgttggg aacaagaagg aactacagtt gaggccctta tgatgggaga acctttcttt     1440

gattgccaga ttgggtttgt tggttgcaga gccatgtgcc ttaaaggaat tatgggtgtt     1500

aaagattttg aagagaatat gaatagaagt gaaactgaag cctgtttctt catttgtggt     1560

gacaatttga gtacgaaagg tttcacatac cttacaaatt cattgtttga ttaccgaagc     1620

ccagaaaata atggtactcg cgcagaattt atcttggatt caactcatca taaggagaca     1680

tacactgaga tagctggaat gcaacggttt ggggcttttt atatggatta cctgtataca     1740

atggagaaca ctagtggcaa aggttccaca aatcaacaag acttttcttc agggaaaagt     1800

gaagatttgg gaacagttca ggagaagtcc accaaaagcc ttgttatagg tcctcttgat     1860

tttcgtttgg atagcagtgc ggtgcatagg attttgaaaa tgattgtgtg tgccttggaa     1920

catgaatatg aaccatatag caggctaaaa tcagatatta aggatgaaaa tgaaacaata     1980

ctgaatcctg aagaggtggc tcttctggag gaatatattc ctactcgaca tacaagtgtt     2040

actctcctca aatgtacctg cacaatttcc atggctgaat tcaacttgct ggaccattta     2100

ctacctgtca ttatgggaga aaagaactca agtaacttca tgaatactac aaacttccag     2160

tctcttcggc ctttgccatc cattcgaata ttggtggata aaattaatct ggaacattca     2220

gtgccaatgt atgctgaaca gttggtgcat gtggtcagca gccttactca accttctgat     2280

aacctgcttc attattgtta tgtacactgc tatcttaaga tatttggttt ccaggcagga     2340

ctgacgtctt tggattgcag tggatcttac tgcttacctg taccagttat tccctctttc     2400

agcactgctc tttatgggaa acttctgaaa ctccccacat gctggaccaa aagatctcag     2460

attgctataa ctgaaggtat atttgaactt ccaaatctca caattcaagc tacaagagca     2520

cagacacttc tcttgcaagc aatatatcaa agttggtctc atcttggaaa tgtcagctct     2580

tccgcagtga ttgaagcttt gataaatgaa atcttcctaa gtataggtgt gaaatctaag     2640

aatcccctgc caactcttga gggctcaatc cagaatgttg aattgaagta ctgcagcaca     2700

tcattggtca aatgtgcctc tgggaccatg ggatcaataa aaatttgtgc caaagcccca     2760

gttgatagtg gaaaagagaa gttgattccc ttgcttcagg gtccttctga cactaaagac     2820

cttcatagca ccaagtggct caatgagagt agaaagccag agtctctctt agctccagat     2880

ttgatggcct tcacaatcca agttccacaa tatattgact actgccacaa ttccggtgct     2940

gtacttcttt gcagtataca aggactagca gttaatattg acccaatctt atatacgtgg     3000

ctcatctatc agcctcagaa acgaacaagt agacatatgc aacagcagcc tgtggtagct     3060

gttcctcttg ttatgccagt ttgtagaagg aaagaggatg aggtgtctat tggaagtgcc     3120

cccttggcaa agcagcaatc atatcaggcc tctgaatatg ccagcagccc tgtaaaaaca     3180

aaaacggtaa cagaatcccg cccattgtca gttcctgtta aagccatgtt gaatatatct     3240

gaaagctgta gaagtcctga agaaagaatg aaggaattta ttggaattgt ttggaatgca     3300

gtgaagcatc tcacactaca gcttgaagta caatcttgtt gtgtgtttat tccaaatgat     3360

agcctgcctt ccccaagtac aattgtatct ggtgacattc ctggaacagt aagaagttgg     3420

taccatggac aaaccagcat gccgggaaca cttgtcctct gtttgcctca aataaagatt     3480

attagtgctg ggcacaagta tatggaacct ctgcaggaga ttccatttgt tatcccacga     3540

cccatccttg aagaaggtga tgcttttcct tggacgatca gcttgcataa tttcagcata     3600

tatacccttc ttggaaaaca agtgacactt tgcctagtgg aacctatggg ttgcacctcc     3660

actctagctg tcacgtctca aaaactgctt gctacgggac ctgatacacg acattcattt     3720

gttgtctgtc tccatgttga cctagagtca ctagagataa aatgctctaa tccccaggtc     3780

cagctcttct atgaactaac tgatatcatg aataaggtct ggaacaagat tcagaagaga     3840

ggcaatctca acctatctcc aacctctcca gagaccatgg cagggcctgt tcctacttct     3900

ccagttagaa gcagtatagg cacagctcct ccagatacca gcacatgcag cccatctgct     3960

gacattggga ctactactga gggagattct atacaagcag gtgaggaatc accattctca     4020

gattctgtga ccttggaaca aactacaagt aatattggag gaaccagtgg acgtgttagt     4080

ttatggatgc agtgggtgct tcccaaaatt actataaagc tctttgctcc agatcctgaa     4140

aataaaggca cagaggtttg tatggtcagt gaactagaag atctcagtgc ttccatagat     4200

gtccaggatg tatataccaa agtgaaatgt aaaatagaga gtttcaatat tgatcactat     4260

agaagcagcc ttggggaaga gtgttggtct ttggggcaat gtggaggtgt cttcctttcc     4320

tgtactgaca agctgaacag acgcaccttg ttggttcgac ccatcagcaa gcaggaccct     4380

ttcagtaatt gctctggctt ctttccttct acaactacaa aacttctaga tggcactcat     4440

cagcagcatg gattcctctc tctgacatac acaaaagctg taacaaaaaa tgtccgccac     4500

aagttaacat caagaaatga gcgaagaagt tttcataagt tatctgaagg cctaatggat     4560

ggttctcctc attttcttca tgaaattctt ctttcagcac aagcttttga tattgttctt     4620

tattttcctt tacttaatgc cattgcaagt atatttcaag caaaactacc aaagacccaa     4680

aaagagaaaa gaaaatctcc tggtcagccc atgaggaccc atacactgac atcccgcaat     4740

ttacctttga tttatgtcaa cacaagtgta atcagaattt ttattccaaa aacagaagaa     4800

atgcagccaa ctgttgaagc taatcaggca gcaaaagaag acactgtggt tttgaagatt     4860

ggctctgttg ccatggctcc ccaggctgac aatccccttg gcagatctgt ccttaggaaa     4920

gatatttacc agagagcctt gaacttagga attcttcgag atcctggatc agaaatcgaa     4980

gacagacaat accaaataga tctgcagtcc atcaatattg gtactgcaca gtggcatcaa     5040

ctaaaaccag agaaggaaag tgtctcagga ggggtggtaa cagagactga aaggaattct     5100

caaaatccag cccttgagtg gaatatggcc agcagcatac ggcggcatca agaaaggaga     5160

gcaattttga cccccgtttt gacagatttt tctgtccgaa taactggagc acctgctgtc     5220

attttcacca aagtagtttc tccagaaaat ttgcatactg aggagatttt agtgtgtggc     5280

cattccttag aagtgaatat aaccacaaac ctggacttct tcctaagtgt ggctcaagtt     5340

caactcttac atcagttaat agtagcaaat atgactggac tggaaccatc aaacaaggct     5400

gcagagatct ctaaacaaga acagaaaaaa gtggatatat ttgatggagg catggctgaa     5460

acctcatctc gctacagtgg tgctcaggat agtggaattg gcagtgacag tgttaaaatc     5520

agaatagtgc aaatagagca gcacagtggt gccagtcagc atcgcattgc ccgtccctca     5580

cgccagtcat caattgtaaa aaatctaaat tttattccct ttgacatatt tattactgca     5640

agtagaatct cactaatgac ctattcctgt atggccttat ccaaatcgaa atcacaagaa     5700

cagaagaata atgaaaaaac agacaagagt tcattaaatc tcccagaagt tgattcagat     5760

gttgctaagc ccaaccaggc atgtatttcc acggtgacag cagaagatct cttaaggagc     5820

agcatttctt ttccttcagg gaaaaaaata ggggtcctct ctcttgaaag tcttcatgca     5880

tccacaaggt catctgctag acaagcactt ggtataacta ttgttcggca gcctggtcga     5940

agaggaactg gtgacttaca gctagagcct tttctgtact ttattgtgtc ccagccttcc     6000

ttgcttctga gttgtcacca cagaaagcag cgagtggaag tatccatttt tgatgctgtg     6060

cttaaagggg tggcctctga ttacaaatgt atagatcctg ggaagactct gcctgaagcc     6120

cttgattatt gcactgtttg gctacagaca gtgcctggag aaatagacag caaaagtggt     6180

attccacctt cctttataac actacagatt aaagactttc tgaatggacc agcggatgtc     6240

aatttggata tatcaaagcc tttgaaagca aacctgagtt tcaccaaact ggatcagata     6300

aacctttttt taaagaagat aaaaaatgca cacagtttgg cacatagtga agagacttca     6360

gccatgtcca acaccatggt gaataaggat gatcttccag tctccaaata ttaccgtgga     6420

aagttgtcta aacccaaaat tcatggtgat ggagtgcaaa agatttcagc tcaagaaaac     6480

atgtggagag ctgtttcctg ctttcaaaaa atttctgttc aaactactca gattgtgatc     6540

tccatggaaa ctgtacccca taccagcaaa ccatgcctgt tagcatctct ctcaaacctc     6600

aatggaagcc ttagtgtcaa ggcaacacaa aaagtacctg gcataattct tgggtcatca     6660

tttctactca gtataaacga ttttctcctt aaaacaagtc tcaaagaaag aagccgcatt     6720

ctgataggac catgttgtgc tactgccaat ctggaagcta agtggtgtaa acacagcggg     6780

aatccaggcc cagaacaatc cataccaaaa atatccattg acttaagagg aggtctacta     6840

caggtcttct ggggtcaaga acatttgaat tgtttagttc ttctacatga attactcaat     6900

ggatacctta atgaggaggg aaattttgaa gtacaagttt ctgaaccagt gcctcaaatg     6960

tcatctcctg tggaaaagaa tcagacattt aaaagtgaac aaagttcaga tgacctacgg     7020

acaggtctat ttcagtatgt acaggatgct gaatctttga aattgcctgg ggtctatgaa     7080

gtcttatttt ataatgaaac tgaagattgc ccagggatga tgttatggag atatccagaa     7140

cctagagtac tcacccttgt acgaataact cctgtacctt ttaacaccac agaggatcca     7200

gatattagca cagcagacct tggtgatgtg ctacaggttc cttgtagctt ggaatactgg     7260

gatgaactcc agaaggtttt tgttgcattt agagaattta atctgtctga aagcaaagtt     7320

tgtgaactgc agttgccgga tatcaatctc gtgaatgacc agaagaaatt agtatcttca     7380

gatctttgga gaattgtctt gaacagcagt caaaatggag ctgatgacca aagctctgca     7440

agtgagtctg gttctcaaag cacttgtgat ccacttgtga ctccaacagc cctggctgcc     7500

tgtaccagag ttgactcctg ctttacccca tggtttgtcc catccctttg cgtttctttc     7560

cagtttgctc acctggaatt ccatctttgt catcaccttg accaactagg cacagctgca     7620

ccacagtacc tacagccatt tgtttccgac agaaatatgc catctgaact agaatacatg     7680

attgtttcct tcagagaacc acacatgtat cttcgacagt ggaataatgg ttctgtctgt     7740

caggagatcc agttcttagc tcaagcagac tgtaaacttc tagagtgcag aaatgtcact     7800

atgcaaagtg tggtgaaacc cttcagcatc ttcgggcaga tggcagtttc cagcgatgta     7860

gtggaaaagc tgcttgactg caccgtgata gttgattctg tatttgtaaa ccttggacag     7920

catgtagtcc attcactaaa cactgcaata caagcttggc aacagaacaa atgccctgag     7980

gtagaggagt tggtcttcag ccattttgtg atctgtaatg acacacagga gacactgcgg     8040

tttggccagg tggatactga tgaaaatatt ctgctggcga gtctccacag tcaccagtac     8100

agctggcgct ctcacaaatc cccacagctg ttacacatct gtattgaagg ttggggcaac     8160

tggcgttggt cagagccttt cagtgtggac catgccggga cttttattag aacaattcag     8220

tacaggggtc gaactgcttc tctcatcatc aaggttcagc aactcaatgg agtacaaaaa     8280

cagattatca tctgtggaag acagatcatc tgtagttact tgtctcaaag catagaacta     8340

aaagtcgttc agcattacat tggtcaagat ggacaagctg tagttcggga acattttgac     8400

tgcctcacag ccaaacagaa attgccttcg tacatactag aaaacaatga actgacggag     8460

ctgtgtgtga aggccaaagg agatgaagac tggtcaagag atgtgtgcct ggaatccaaa     8520

gcccctgagt acagcattgt cattcaggtg ccatcttcaa acagttccat tatttatgtc     8580

tggtgcacag ttttgacttt agaacccaac tctcaagtgc aacaacgaat gattgtgttc     8640

agccctcttt ttatcatgag gagtcatctt ccagacccca ttatcataca tttggagaaa     8700

aggagtctgg gattgagtga aacacaaatt attccaggaa aagggcagga aaaaccactg     8760

caaaacatag aacctgacct tgtacatcac ctgacattcc aagcaagaga agaatatgat     8820

ccttcagatt gtgcagttcc catctcaaca tccctcatta agcaaatagc cactaaggta     8880

caccctggag gcacagttaa tcagatcctt gacgaattct atgggccaga aaagtcgctt     8940

caacccatat ggccctataa taagaaggat tctgacagga atgaacagct aagtcagtgg     9000

gatagcccaa tgcgagtgaa gctgtcaatc tggaagccat atgttagaac tttgttgata     9060

gaacttctgc cctgggccct gcttatcaat gaatccaaat gggacctctg gctatttgaa     9120

ggagagaaaa ttgttctaca ggttcctgct ggcaaaatta ttattcctcc taattttcag     9180

gaagcttttc aaattggaat atactgggca aatacaaaca ctgtgcacaa gtcagtagca     9240

attaaactgg tccataacct gacatctcca aagtggaaag atggaggtaa tggtgaagtt     9300

gtgacactgg atgaagaagc gtttgttgat actgaaataa gacttggtgc ttttccagga     9360

catcagaagt tatgtcagtt ctgcatttcc tccatggtac agcaaggtat acaaattatt     9420

cagattgaag acaagactac aataatcaat aatacaccat atcaaatatt ttataaacca     9480

cagctatctg tctgcaatcc ccattctgga aaggagtatt ttcgtgttcc agacagtgct     9540

acttttagca tttgcccagg tggagagcag cctgctatga aatccagctc ccttccttgc     9600

tgggacttga tgcctgacat cagtcagtca gtactggatg catccctgct tcagaaacag     9660

atcatgctgg gcttttctcc tgccccaggt gctgacagct cacagtgctg gagcctgcca     9720

gctatagtta gaccagagtt tcccagacag agtgtggcag tacccctcgg gaatttccgg     9780

gaaaatggat tctgtaccag ggctatagtg ctgacatatc aagaacacct cggagtgact     9840

tatttaaccc tctcagaaga ccctagtcct cgagtaatta tccacaatag atgtccagta     9900

aaaatgctta taaaggaaaa cattaaagat attccaaagt ttgaggttta ttgcaaaaaa     9960

attccctccg agtgctcaat tcatcatgag ctgtatcatc agatttccag ttatccggac    10020

tgcaagacca aagacttact tccaagccta cttttgagag ttgaacctct agatgaagta    10080

acaactgagt ggagtgatgc cattgacatc aacagtcagg gaacacaggt tgtgttcctg    10140

actggctttg gctatgtgta tgtggatgtt gtacatcagt gtggcacagt cttcatcact    10200

gtggccccag aaggaaaagc aggacctatt ttaaccaata ccaacagagc gccagagaag    10260

attgttacat ttaaaatgtt catcactcag ttaagcctgg cagtgtttga tgacctcacc    10320

caccacaaag catcagctga gcttctgaga ctcacactgg acaacatttt tctctgtgtg    10380

gccccgggag ctggtcccct ccctggggaa gagcctgtgg ctgcgttgtt tgaactttac    10440

tgtgtggaga tctgctgtgg ggacctgcag ctagacaacc agctttataa caagtccaat    10500

ttccactttg ctgtcttagt ctgccaggga gaaaaagcag aacccattca gtgttccaaa    10560

atgcagagtc tcctcatatc caacaaagag ttggaagaat acaaggaaaa atgttttatc    10620

aaactttgca tcaccttaaa tgaaggcaag agcatcctct gtgatattaa tgagttcagc    10680

tttgaattaa aacctgctcg gttatacgtg gaagacacat ttgtatacta catcaagact    10740

ttgtttgaca cctaccttcc taacagcagg ttggctggtc actccacaca cctctccggg    10800

ggtaaacagg tgttgcccat gcaggtcaca cagcacgcca gggccttggt gaatcctgtg    10860

aagttacgga aactggtgat ccagccagta aatttgctcg tcagcatcca cgcttccctc    10920

aagctgtaca tagcctcaga ccacactcct ctctccttct cggtgtttga aagaggaccc    10980

atcttcacca ctgcgaggca gcttgtgcac gccctggcaa tgcactatgc cgctggggcc    11040

ctttttagag caggctgggt agttgggtct ctggatattc ttggcagccc tgcaagcctg    11100

gtgagaagca tcgggaacgg ggtcgccgac ttcttcaggc ttccgtatga ggggctgacc    11160

cggggccctg gagccttcgt gagtggcgtc tccagaggga ccacatcgtt tgtaaagcac    11220

atctccaaag gtaccctcac atccatcacc aacctcgcca caagcctggc ccggaacatg    11280

gaccggctct cactggatga ggagcactac aaccggcagg aggagtggcg gcggcagctc    11340

cccgagagcc tgggcgaggg gcttcgacag ggcctgtccc ggctgggcat cagcctgctt    11400

ggtgcaattg ctggtatagt tgatcagccg atgcagaact tccagaaaac atctgaggca    11460

caggcttcag caggacacaa ggccaagggt gtcatctcgg gtgtggggaa aggaatcatg    11520

ggggtgttca caaagcccat cggaggagct gctgagctgg tgtcacagac tggctatggt    11580

attttacatg gagctggact ttctcagctt cccaaacagc gccatcagcc aagtgatcta    11640

catgctgacc aggctccaaa cagccatgtc aaatatgtct ggaaaatgct tcagtctctg    11700

ggcagaccag aagtccacat ggccctggac gtggttctgg tgaggggctc aggccaggag    11760

catgaagggt gcttgctgct gacatcagaa gtgctcttcg tggtgagtgt cagtgaggac    11820

acacagcagc aggccttccc cgtcacagaa atcgactgtg cacaggacag caagcagaac    11880

aacttactca cagtgcagct caagcagcca agagtggcct gtgatgtgga ggtagatgga    11940

gtccgagaga gactgtcaga gcaacagtac aacagactgg tggactacat cacaaagaca    12000

tcttgtcacc tggcccccag ctgttcttcc atgcaaatac catgccctgt ggtggctgca    12060

gaacctcccc cctccactgt taaaacatac cattacctgg ttgatccaca ttttgctcag    12120

gtcttcctta gtaaatttac catggtgaaa aataaagccc tgaggaaagg gtttccttga    12180

gtcccctctg aggtgtttat tcctgcttgt gtgatttagt ttttgggttt ctttgagaca    12240

gggtctcact gcattgccct tgctgacctc aaattctggg gttcaagcaa tcctcccacc    12300

tcaacccaca agtagctacg actgcaagca cctgccacca taaagggctg cattttgcca    12360

ccataaaggg ctgcattttt ttaaaaagcc taggcagctc taacatcatc tgatatggac    12420

acaaggccaa cagtttcctt atttacatcc ttacctctaa aagatacttc aaagtgacaa    12480

aaacgtgttc cttccccact tagagacaat gattaacagg gccctatatg ttcttaccac    12540

atacagagga tgcatttatt tttgctctat gacacttgca aaaatctcta ctgtaattaa    12600

tttgggtcta ttattaactc tctgttccat catagaatgt ggccaggcct tacaatggag    12660

agccagagtt aaaacttcaa gttgcatctg tttttgggct gagtcaccac ctttgcctca    12720

tgctcctttg tctgcaaagg cctaggattc tttctttaaa tgaaatgctt aggactttgt    12780

ggcttgttac atttgtcatt taactgcagt gctattcttt gaaagctgct atgtgtattt    12840

tctctgaagt ctgcatttta ctaaaattta caacagtctg atgattgatt gattactgtc    12900

caggtacatt ttagaaaaag tgttcttctt ccagtttgtt ttactaagca aactttgagt    12960

aaatcctttg tcctatattg aatccagtcc caaagtgttc aggtgagttt ctctagttcc    13020

ataaacaaaa catacatagt gggaactccc tggtatgcca tagagcacac aagaacccca    13080

atattaatgc taacaattat accagtccat tttgtttatt ctgtggaatt gacttgacaa    13140

agcatgaaga tattcccagt gtctgtctga taatattttg catctaagaa tgggtttgac    13200

tcaagatctt gggttaccaa gatgtcttaa atgttcagta aatatctttc ttacagtcca    13260

gtagcttaga gcatgtttgc tgattgatat tacatttaaa cttggggcta cagcttgtta    13320

cctagaattt tgagatacta agagaatgca attttaaatg cccactggtt ttatttgttt    13380

tggagagagg gtctcattct gtcacccagg ctagagtaca gtgggaacag tcatggctca    13440

ctgcagctta agctcactgc ctgggctcaa gtgatcttac tccagcctcc caagcagctg    13500

ggactacacc accacaggta tgcaccacca tacctggctg atttttaaaa ttttttctag    13560

agatgaggtc tcactatgtt gcccagctgg tctcatactc ctcagttcac gcattcctcc    13620

cacctccacc tcccaaactg ctgggattac aggtgtgagc caccatgccc aacacccact    13680

gatctttaac tctcacatgt tgggcataag aagtcactat ataattgtta ctggaaagca    13740

agacttaacg aacaattctg actatgaaaa atgtctcttt cagtttgttc tgtaaatatt    13800

tagaaaagtg acagctgtca acctcagagt aactatttct aaaaatgtaa atatgtatta    13860

atccttgtat cttttatggt aattttgcat attgatatga attatataaa attgtttaaa    13920

ataaaaggtg tccttgaatt actgaccacc catagatgtc tactgttacc aggttttaca    13980

atgcaaattt tcactaatac ctgggtttaa tacagctcac atcactgaat gttacacatg    14040

agtttaaatg ggtaatatac aggttttgtt ataataaagt tactgattaa attagctttg    14100


<210>  430
<211>  466
<212>  DNA
<213>  homo sapiens

<400>  430
cttgccgcgc tgcactccac cacgcctcct ccaagtccca gcgaacccgc gtgcaacctg       60

tcccgactct agccgcctct tcagctcgcc atggatccca actgctcctg cgccgccggt      120

gactcctgca cctgcgccgg ctcctgcaaa tgcaaagagt gcaaatgcac ctcctgcaag      180

aaaagctgct gctcctgctg ccctgtgggc tgtgccaagt gtgcccaggg ctgcatctgc      240

aaaggggcgt cggacaagtg cagctgctgc gcctgatgct gggacagccc cgctcccaga      300

tgtaaagaac gcgacttcca caaacctgga ttttttatgt acaaccctga ccgtgaccgt      360

ttgctatatt cctttttcta tgaaataatg tgaatgataa taaaacagct ttgacttgaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                     466


<210>  431
<211>  1288
<212>  DNA
<213>  homo sapiens

<400>  431
ttggtttggg ccaggtggac tggaaggggc ggaggtaacc agaagcggct agtggcggct       60

gcctgcgtcc ccaaccccct ccgcgcagcg ctcgcgacac gcgtgccagg agtgggagcg      120

agcggcgggg ccagctgcgt tctgagcctg ggcgcagctg ccatctgctc tgggaagcac      180

cagggtgtcc ccgccgccct cagctcgaag tcagccacca tggaggcgca ggcacaaggt      240

ttgttggaga ctgaaccgtt gcaaggaaca gacgaagatg cagtagccag tgctgacttc      300

tctagcatgc tctctgagga ggaaaaggaa gagttaaaag cagagttagt tcagctagaa      360

gacgaaatta caacactacg acaagttttg tcagcgaaag aaaggcatct agttgagata      420

aaacaaaaac tcggcatgaa cctgatgaat gaattaaaac agaacttcag caaaagctgg      480

catgacatgc agactaccac tgcctacaag aaaacacatg aaaccctgag tcacgcaggg      540

caaaaggcaa ctgcagcttt cagcaacgtt ggaacggcca tcagcaagaa gttcggagac      600

atgagacgaa agtaggcggt acgaacccta atggaggcag ttttgaggag gtcctcagct      660

ccacggccca tgccagtgcc cagagcttgg caggaggctc ccggcggacc aaggaggagg      720

agctgcagtg ctaagtccag ccagcgtgca gctgcatcca gaaaccggcc actacccagc      780

ccatctctgc ctgtgcttat ccagataaga agaccaaaat cccgctggga aaaacccagg      840

ccttgacatt gttattcaaa tggcccctcc agaaagttta atgatttcca tttgtatttg      900

tgttgatgat ggaccacttg accatcacat ttcagtattc atagatgact gtcacatttt      960

aaaatgttcc cacttgagca ggtacacaac tggtcataat tcctgtctgt gtaattcgat     1020

gtatattttt ccaaacatgt agctattgtt tgctttgatt tttgcttggc ctcctttatg     1080

atgtgcatgt ccttgaaggc tgaatgaaca gtccctttca gttcagcaga tcaacaggat     1140

ggagctcttc atgactgtct ccagcaatag gatgatttac tataaatttc atccaactac     1200

ttgtgatctc tctcacctac atcaattatg tatgttaatt tcagcaatta aaagaattga     1260

ttttaatgac aaaaaaaaaa aaaaaaaa                                        1288


<210>  432
<211>  6410
<212>  DNA
<213>  homo sapiens

<400>  432
cttctctccc agtgcgagag cgcggcggcg gcagctgaag acccggccgc ccagatgatg       60

cggtggtggg ggacctgccg gcacgcgact ccccccgggc ccaaattgat attcactgat      120

ggactccaaa gaatcattaa ctcctggtag agaagaaaac cccagcagtg tgcttgctca      180

ggagagggga gatgtgatgg acttctataa aaccctaaga ggaggagcta ctgtgaaggt      240

ttctgcgtct tcaccctcac tggctgtcgc ttctcaatca gactccaagc agcgaagact      300

tttggttgat tttccaaaag gctcagtaag caatgcgcag cagccagatc tgtccaaagc      360

agtttcactc tcaatgggac tgtatatggg agagacagaa acaaaagtga tgggaaatga      420

cctgggattc ccacagcagg gccaaatcag cctttcctcg ggggaaacag acttaaagct      480

tttggaagaa agcattgcaa acctcaatag gtcgaccagt gttccagaga accccaagag      540

ttcagcatcc actgctgtgt ctgctgcccc cacagagaag gagtttccaa aaactcactc      600

tgatgtatct tcagaacagc aacatttgaa gggccagact ggcaccaacg gtggcaatgt      660

gaaattgtat accacagacc aaagcacctt tgacattttg caggatttgg agttttcttc      720

tgggtcccca ggtaaagaga cgaatgagag tccttggaga tcagacctgt tgatagatga      780

aaactgtttg ctttctcctc tggcgggaga agacgattca ttccttttgg aaggaaactc      840

gaatgaggac tgcaagcctc tcattttacc ggacactaaa cccaaaatta aggataatgg      900

agatctggtt ttgtcaagcc ccagtaatgt aacactgccc caagtgaaaa cagaaaaaga      960

agatttcatc gaactctgca cccctggggt aattaagcaa gagaaactgg gcacagttta     1020

ctgtcaggca agctttcctg gagcaaatat aattggtaat aaaatgtctg ccatttctgt     1080

tcatggtgtg agtacctctg gaggacagat gtaccactat gacatgaata cagcatccct     1140

ttctcaacag caggatcaga agcctatttt taatgtcatt ccaccaattc ccgttggttc     1200

cgaaaattgg aataggtgcc aaggatctgg agatgacaac ttgacttctc tggggactct     1260

gaacttccct ggtcgaacag ttttttctaa tggctattca agccccagca tgagaccaga     1320

tgtaagctct cctccatcca gctcctcaac agcaacaaca ggaccacctc ccaaactctg     1380

cctggtgtgc tctgatgaag cttcaggatg tcattatgga gtcttaactt gtggaagctg     1440

taaagttttc ttcaaaagag cagtggaagg acagcacaat tacctatgtg ctggaaggaa     1500

tgattgcatc atcgataaaa ttcgaagaaa aaactgccca gcatgccgct atcgaaaatg     1560

tcttcaggct ggaatgaacc tggaagctcg aaaaacaaag aaaaaaataa aaggaattca     1620

gcaggccact acaggagtct cacaagaaac ctctgaaaat cctggtaaca aaacaatagt     1680

tcctgcaacg ttaccacaac tcacccctac cctggtgtca ctgttggagg ttattgaacc     1740

tgaagtgtta tatgcaggat atgatagctc tgttccagac tcaacttgga ggatcatgac     1800

tacgctcaac atgttaggag ggcggcaagt gattgcagca gtgaaatggg caaaggcaat     1860

accaggtttc aggaacttac acctggatga ccaaatgacc ctactgcagt actcctggat     1920

gtttcttatg gcatttgctc tggggtggag atcatataga caatcaagtg caaacctgct     1980

gtgttttgct cctgatctga ttattaatga gcagagaatg actctaccct gcatgtacga     2040

ccaatgtaaa cacatgctgt atgtttcctc tgagttacac aggcttcagg tatcttatga     2100

agagtatctc tgtatgaaaa ccttactgct tctctcttca gttcctaagg acggtctgaa     2160

gagccaagag ctatttgatg aaattagaat gacctacatc aaagagctag gaaaagccat     2220

tgtcaagagg gaaggaaact ccagccagaa ctggcagcgg ttttatcaac tgacaaaact     2280

cttggattct atgcatgaag tggttgaaaa tctccttaac tattgcttcc aaacattttt     2340

ggataagacc atgagtattg aattccccga gatgttagct gaaatcatca ccaatcagat     2400

accaaaatat tcaaatggaa atatcaaaaa acttctgttt catcaaaagt gactgcctta     2460

ataagaatgg ttgccttaaa gaaagtcgaa ttaatagctt ttattgtata aactatcagt     2520

ttgtcctgta gaggttttgt tgttttattt tttattgttt tcatctgttg ttttgtttta     2580

aatacgcact acatgtggtt tatagagggc caagacttgg caacagaagc agttgagtcg     2640

tcatcacttt tcagtgatgg gagagtagat ggtgaaattt attagttaat atatcccaga     2700

aattagaaac cttaatatgt ggacgtaatc tccacagtca aagaaggatg gcacctaaac     2760

caccagtgcc caaagtctgt gtgatgaact ttctcttcat actttttttc acagttggct     2820

ggatgaaatt ttctagactt tctgttggtg tatccccccc ctgtatagtt aggatagcat     2880

ttttgattta tgcatggaaa cctgaaaaaa agtttacaag tgtatatcag aaaagggaag     2940

ttgtgccttt tatagctatt actgtctggt tttaacaatt tcctttatat ttagtgaact     3000

acgcttgctc attttttctt acataatttt ttattcaagt tattgtacag ctgtttaaga     3060

tgggcagcta gttcgtagct ttcccaaata aactctaaac attaatcaat catctgtgtg     3120

aaaatgggtt ggtgcttcta acctgatggc acttagctat cagaagacca caaaaattga     3180

ctcaaatctc cagtattctt gtcaaaaaaa aaaaaaaaaa agctcatatt ttgtatatat     3240

ctgcttcagt ggagaattat ataggttgtg caaattaaca gtcctaactg gtatagagca     3300

cctagtccag tgacctgctg ggtaaactgt ggatgatggt tgcaaaagac taatttaaaa     3360

aataactacc aagaggccct gtctgtacct aacgccctat ttttgcaatg gctatatggc     3420

aagaaagctg gtaaactatt tgtctttcag gaccttttga agtagtttgt ataacttctt     3480

aaaagttgtg attccagata accagctgta acacagctga gagactttta atcagacaaa     3540

gtaattcctc tcactaaact ttacccaaaa actaaatctc taatatggca aaaatggcta     3600

gacacccatt ttcacattcc catctgtcac caattggtta atctttcctg atggtacagg     3660

aaagctcagc tactgatttt tgtgatttag aactgtatgt cagacatcca tgtttgtaaa     3720

actacacatc cctaatgtgt gccatagagt ttaacacaag tcctgtgaat ttcttcactg     3780

ttgaaaatta ttttaaacaa aatagaagct gtagtagccc tttctgtgtg caccttacca     3840

actttctgta aactcaaaac ttaacatatt tactaagcca caagaaattt gatttctatt     3900

caaggtggcc aaattatttg tgtaatagaa aactgaaaat ctaatattaa aaatatggaa     3960

cttctaatat atttttatat ttagttatag tttcagatat atatcatatt ggtattcact     4020

aatctgggaa gggaagggct actgcagctt tacatgcaat ttattaaaat gattgtaaaa     4080

tagcttgtat agtgtaaaat aagaatgatt tttagatgag attgttttat catgacatgt     4140

tatatatttt ttgtaggggt caaagaaatg ctgatggata acctatatga tttatagttt     4200

gtacatgcat tcatacaggc agcgatggtc tcagaaacca aacagtttgc tctaggggaa     4260

gagggagatg gagactggtc ctgtgtgcag tgaaggttgc tgaggctctg acccagtgag     4320

attacagagg aagttatcct ctgcctccca ttctgaccac ccttctcatt ccaacagtga     4380

gtctgtcagc gcaggtttag tttactcaat ctccccttgc actaaagtat gtaaagtatg     4440

taaacaggag acaggaaggt ggtgcttaca tccttaaagg caccatctaa tagcgggtta     4500

ctttcacata cagccctccc ccagcagttg aatgacaaca gaagcttcag aagtttggca     4560

atagtttgca tagaggtacc agcaatatgt aaatagtgca gaatctcata ggttgccaat     4620

aatacactaa ttcctttcta tcctacaaca agagtttatt tccaaataaa atgaggacat     4680

gtttttgttt tctttgaatg ctttttgaat gttatttgtt attttcagta ttttggagaa     4740

attatttaat aaaaaaacaa tcatttgctt tttgaatgct ctctaaaagg gaatgtaata     4800

ttttaagatg gtgtgtaacc cggctggata aatttttggt gcctaagaaa actgcttgaa     4860

tattcttatc aatgacagtg ttaagtttca aaaagagctt ctaaaacgta gattatcatt     4920

cctttataga atgttatgtg gttaaaacca gaaagcacat ctcacacatt aatctgattt     4980

tcatcccaac aatcttggcg ctcaaaaaat agaactcaat gagaaaaaga agattatgtg     5040

cacttcgttg tcaataataa gtcaactgat gctcatcgac aactatagga ggcttttcat     5100

taaatgggaa aagaagctgt gcccttttag gatacgtggg ggaaaagaaa gtcatcttaa     5160

ttatgtttaa ttgtggattt aagtgctata tggtggtgct gtttgaaagc agatttattt     5220

cctatgtatg tgttatctgg ccatcccaac ccaaactgtt gaagtttgta gtaacttcag     5280

tgagagttgg ttactcacaa caaatcctga aaagtatttt tagtgtttgt aggtattctg     5340

tgggatacta tacaagcaga actgaggcac ttaggacata acacttttgg ggtatatata     5400

tccaaatgcc taaaactatg ggaggaaacc ttggccaccc caaaaggaaa actaacatga     5460

tttgtgtcta tgaagtgctg gataattagc atgggatgag ctctgggcat gccatgaagg     5520

aaagccacgc tcccttcaga attcagaggc agggagcaat tccagtttca cctaagtctc     5580

ataattttag ttccctttta aaaaccctga aaactacatc accatggaat gaaaaatatt     5640

gttatacaat acattgatct gtcaaacttc cagaaccatg gtagccttca gtgagatttc     5700

catcttggct ggtcactccc tgactgtagc tgtaggtgaa tgtgtttttg tgtgtgtgtg     5760

tctggtttta gtgtcagaag ggaaataaaa gtgtaaggag gacactttaa accctttggg     5820

tggagtttcg taatttccca gactattttc aagcaacctg gtccacccag gattagtgac     5880

caggttttca ggaaaggatt tgcttctctc tagaaaatgt ctgaaaggat tttattttct     5940

gatgaaaggc tgtatgaaaa taccctcctc aaataacttg cttaactaca tatagattca     6000

agtgtgtcaa tattctattt tgtatattaa atgctatata atggggacaa atctatatta     6060

tactgtgtat ggcattatta agaagctttt tcattatttt ttatcacagt aattttaaaa     6120

tgtgtaaaaa ttaaaaccag tgactcctgt ttaaaaataa aagttgtagt tttttattca     6180

tgctgaataa taatctgtag ttaaaaaaaa agtgtctttt tacctacgca gtgaaatgtc     6240

agactgtaaa accttgtgtg gaaatgttta acttttattt tttcatttaa atttgctgtt     6300

ctggtattac caaaccacac atttgtaccg aattggcagt aaatgttagc catttacagc     6360

aatgccaaat atggagaaac atcataataa aaaaatctgc tttttcatta                6410


<210>  433
<211>  7286
<212>  DNA
<213>  homo sapiens

<400>  433
aggttatgta agggtttgct ttcaccccat tcaaaaggta cctcttcctc ttctcttgct       60

ccctctcgcc ctcattcttg tgcctatgca gacatttgag tagaggcgaa tcactttcac      120

ttctgctggg gaaattgcaa cacgcttctt taaatggcag agagaaggag aaaacttaga      180

tcttctgata ccaaatcact ggaccttaga aggtcagaaa tctttcaagc cctgcaggac      240

cgtaaaatgc gcatgtgtcc aacggaagca ctggggcatg agtggggaag gaatagaaac      300

agaaagaggg taagagaaga aaaaagggaa agtggtgaag gcagggagga aaattgctta      360

gtgtgaatat gcacgcattc atttagtttt caaatccttg ttgagcatga taaaattccc      420

agcatcagac ctcacatgtt ggtttccatt aggatctgcc tgggggaata tctgctgaat      480

cagtggctct gagctgaact aggaaattca ccataattag gagagtcact gtatttctct      540

ccaaaaaaaa aaaagttata cccgagagac aggatcttct gatctgaaat tttcttcact      600

tctgaaattc tctggtttgt gctcatcgtt ggtagctatt tgttcatcaa gagttgtgta      660

gctggcttct tctgaaaaaa ggaatctgcg tcatatctaa gtcagatttc attctggtgc      720

tctcagagca gttagcccag gaaaggggcc agcttctgtg acgactgctg cagaggcagg      780

tgcagtttgt gtgccacaga tattaacttt gataagcact taatgagtgc cttctctgtg      840

cgagaatggg gaggaacaaa atgcagctcc taccctcctc gggctttagt tgtaccttaa      900

taacaggaat tttcatctgc ctggctcctt tcctcaaaga acaaagaaga ctttgcttca      960

ttaaagtgtc tgagaaggaa gttgatattc actgatggac tccaaagaat cattaactcc     1020

tggtagagaa gaaaacccca gcagtgtgct tgctcaggag aggggagatg tgatggactt     1080

ctataaaacc ctaagaggag gagctactgt gaaggtttct gcgtcttcac cctcactggc     1140

tgtcgcttct caatcagact ccaagcagcg aagacttttg gttgattttc caaaaggctc     1200

agtaagcaat gcgcagcagc cagatctgtc caaagcagtt tcactctcaa tgggactgta     1260

tatgggagag acagaaacaa aagtgatggg aaatgacctg ggattcccac agcagggcca     1320

aatcagcctt tcctcggggg aaacagactt aaagcttttg gaagaaagca ttgcaaacct     1380

caataggtcg accagtgttc cagagaaccc caagagttca gcatccactg ctgtgtctgc     1440

tgcccccaca gagaaggagt ttccaaaaac tcactctgat gtatcttcag aacagcaaca     1500

tttgaagggc cagactggca ccaacggtgg caatgtgaaa ttgtatacca cagaccaaag     1560

cacctttgac attttgcagg atttggagtt ttcttctggg tccccaggta aagagacgaa     1620

tgagagtcct tggagatcag acctgttgat agatgaaaac tgtttgcttt ctcctctggc     1680

gggagaagac gattcattcc ttttggaagg aaactcgaat gaggactgca agcctctcat     1740

tttaccggac actaaaccca aaattaagga taatggagat ctggttttgt caagccccag     1800

taatgtaaca ctgccccaag tgaaaacaga aaaagaagat ttcatcgaac tctgcacccc     1860

tggggtaatt aagcaagaga aactgggcac agtttactgt caggcaagct ttcctggagc     1920

aaatataatt ggtaataaaa tgtctgccat ttctgttcat ggtgtgagta cctctggagg     1980

acagatgtac cactatgaca tgaatacagc atccctttct caacagcagg atcagaagcc     2040

tatttttaat gtcattccac caattcccgt tggttccgaa aattggaata ggtgccaagg     2100

atctggagat gacaacttga cttctctggg gactctgaac ttccctggtc gaacagtttt     2160

ttctaatggc tattcaagcc ccagcatgag accagatgta agctctcctc catccagctc     2220

ctcaacagca acaacaggac cacctcccaa actctgcctg gtgtgctctg atgaagcttc     2280

aggatgtcat tatggagtct taacttgtgg aagctgtaaa gttttcttca aaagagcagt     2340

ggaaggacag cacaattacc tatgtgctgg aaggaatgat tgcatcatcg ataaaattcg     2400

aagaaaaaac tgcccagcat gccgctatcg aaaatgtctt caggctggaa tgaacctgga     2460

agctcgaaaa acaaagaaaa aaataaaagg aattcagcag gccactacag gagtctcaca     2520

agaaacctct gaaaatcctg gtaacaaaac aatagttcct gcaacgttac cacaactcac     2580

ccctaccctg gtgtcactgt tggaggttat tgaacctgaa gtgttatatg caggatatga     2640

tagctctgtt ccagactcaa cttggaggat catgactacg ctcaacatgt taggagggcg     2700

gcaagtgatt gcagcagtga aatgggcaaa ggcaatacca ggtttcagga acttacacct     2760

ggatgaccaa atgaccctac tgcagtactc ctggatgttt cttatggcat ttgctctggg     2820

gtggagatca tatagacaat caagtgcaaa cctgctgtgt tttgctcctg atctgattat     2880

taatgagcag agaatgactc taccctgcat gtacgaccaa tgtaaacaca tgctgtatgt     2940

ttcctctgag ttacacaggc ttcaggtatc ttatgaagag tatctctgta tgaaaacctt     3000

actgcttctc tcttcagttc ctaaggacgg tctgaagagc caagagctat ttgatgaaat     3060

tagaatgacc tacatcaaag agctaggaaa agccattgtc aagagggaag gaaactccag     3120

ccagaactgg cagcggtttt atcaactgac aaaactcttg gattctatgc atgaagtggt     3180

tgaaaatctc cttaactatt gcttccaaac atttttggat aagaccatga gtattgaatt     3240

ccccgagatg ttagctgaaa tcatcaccaa tcagatacca aaatattcaa atggaaatat     3300

caaaaaactt ctgtttcatc aaaagtgact gccttaataa gaatggttgc cttaaagaaa     3360

gtcgaattaa tagcttttat tgtataaact atcagtttgt cctgtagagg ttttgttgtt     3420

ttatttttta ttgttttcat ctgttgtttt gttttaaata cgcactacat gtggtttata     3480

gagggccaag acttggcaac agaagcagtt gagtcgtcat cacttttcag tgatgggaga     3540

gtagatggtg aaatttatta gttaatatat cccagaaatt agaaacctta atatgtggac     3600

gtaatctcca cagtcaaaga aggatggcac ctaaaccacc agtgcccaaa gtctgtgtga     3660

tgaactttct cttcatactt tttttcacag ttggctggat gaaattttct agactttctg     3720

ttggtgtatc ccccccctgt atagttagga tagcattttt gatttatgca tggaaacctg     3780

aaaaaaagtt tacaagtgta tatcagaaaa gggaagttgt gccttttata gctattactg     3840

tctggtttta acaatttcct ttatatttag tgaactacgc ttgctcattt tttcttacat     3900

aattttttat tcaagttatt gtacagctgt ttaagatggg cagctagttc gtagctttcc     3960

caaataaact ctaaacatta atcaatcatc tgtgtgaaaa tgggttggtg cttctaacct     4020

gatggcactt agctatcaga agaccacaaa aattgactca aatctccagt attcttgtca     4080

aaaaaaaaaa aaaaaaagct catattttgt atatatctgc ttcagtggag aattatatag     4140

gttgtgcaaa ttaacagtcc taactggtat agagcaccta gtccagtgac ctgctgggta     4200

aactgtggat gatggttgca aaagactaat ttaaaaaata actaccaaga ggccctgtct     4260

gtacctaacg ccctattttt gcaatggcta tatggcaaga aagctggtaa actatttgtc     4320

tttcaggacc ttttgaagta gtttgtataa cttcttaaaa gttgtgattc cagataacca     4380

gctgtaacac agctgagaga cttttaatca gacaaagtaa ttcctctcac taaactttac     4440

ccaaaaacta aatctctaat atggcaaaaa tggctagaca cccattttca cattcccatc     4500

tgtcaccaat tggttaatct ttcctgatgg tacaggaaag ctcagctact gatttttgtg     4560

atttagaact gtatgtcaga catccatgtt tgtaaaacta cacatcccta atgtgtgcca     4620

tagagtttaa cacaagtcct gtgaatttct tcactgttga aaattatttt aaacaaaata     4680

gaagctgtag tagccctttc tgtgtgcacc ttaccaactt tctgtaaact caaaacttaa     4740

catatttact aagccacaag aaatttgatt tctattcaag gtggccaaat tatttgtgta     4800

atagaaaact gaaaatctaa tattaaaaat atggaacttc taatatattt ttatatttag     4860

ttatagtttc agatatatat catattggta ttcactaatc tgggaaggga agggctactg     4920

cagctttaca tgcaatttat taaaatgatt gtaaaatagc ttgtatagtg taaaataaga     4980

atgattttta gatgagattg ttttatcatg acatgttata tattttttgt aggggtcaaa     5040

gaaatgctga tggataacct atatgattta tagtttgtac atgcattcat acaggcagcg     5100

atggtctcag aaaccaaaca gtttgctcta ggggaagagg gagatggaga ctggtcctgt     5160

gtgcagtgaa ggttgctgag gctctgaccc agtgagatta cagaggaagt tatcctctgc     5220

ctcccattct gaccaccctt ctcattccaa cagtgagtct gtcagcgcag gtttagttta     5280

ctcaatctcc ccttgcacta aagtatgtaa agtatgtaaa caggagacag gaaggtggtg     5340

cttacatcct taaaggcacc atctaatagc gggttacttt cacatacagc cctcccccag     5400

cagttgaatg acaacagaag cttcagaagt ttggcaatag tttgcataga ggtaccagca     5460

atatgtaaat agtgcagaat ctcataggtt gccaataata cactaattcc tttctatcct     5520

acaacaagag tttatttcca aataaaatga ggacatgttt ttgttttctt tgaatgcttt     5580

ttgaatgtta tttgttattt tcagtatttt ggagaaatta tttaataaaa aaacaatcat     5640

ttgctttttg aatgctctct aaaagggaat gtaatatttt aagatggtgt gtaacccggc     5700

tggataaatt tttggtgcct aagaaaactg cttgaatatt cttatcaatg acagtgttaa     5760

gtttcaaaaa gagcttctaa aacgtagatt atcattcctt tatagaatgt tatgtggtta     5820

aaaccagaaa gcacatctca cacattaatc tgattttcat cccaacaatc ttggcgctca     5880

aaaaatagaa ctcaatgaga aaaagaagat tatgtgcact tcgttgtcaa taataagtca     5940

actgatgctc atcgacaact ataggaggct tttcattaaa tgggaaaaga agctgtgccc     6000

ttttaggata cgtgggggaa aagaaagtca tcttaattat gtttaattgt ggatttaagt     6060

gctatatggt ggtgctgttt gaaagcagat ttatttccta tgtatgtgtt atctggccat     6120

cccaacccaa actgttgaag tttgtagtaa cttcagtgag agttggttac tcacaacaaa     6180

tcctgaaaag tatttttagt gtttgtaggt attctgtggg atactataca agcagaactg     6240

aggcacttag gacataacac ttttggggta tatatatcca aatgcctaaa actatgggag     6300

gaaaccttgg ccaccccaaa aggaaaacta acatgatttg tgtctatgaa gtgctggata     6360

attagcatgg gatgagctct gggcatgcca tgaaggaaag ccacgctccc ttcagaattc     6420

agaggcaggg agcaattcca gtttcaccta agtctcataa ttttagttcc cttttaaaaa     6480

ccctgaaaac tacatcacca tggaatgaaa aatattgtta tacaatacat tgatctgtca     6540

aacttccaga accatggtag ccttcagtga gatttccatc ttggctggtc actccctgac     6600

tgtagctgta ggtgaatgtg tttttgtgtg tgtgtgtctg gttttagtgt cagaagggaa     6660

ataaaagtgt aaggaggaca ctttaaaccc tttgggtgga gtttcgtaat ttcccagact     6720

attttcaagc aacctggtcc acccaggatt agtgaccagg ttttcaggaa aggatttgct     6780

tctctctaga aaatgtctga aaggatttta ttttctgatg aaaggctgta tgaaaatacc     6840

ctcctcaaat aacttgctta actacatata gattcaagtg tgtcaatatt ctattttgta     6900

tattaaatgc tatataatgg ggacaaatct atattatact gtgtatggca ttattaagaa     6960

gctttttcat tattttttat cacagtaatt ttaaaatgtg taaaaattaa aaccagtgac     7020

tcctgtttaa aaataaaagt tgtagttttt tattcatgct gaataataat ctgtagttaa     7080

aaaaaaagtg tctttttacc tacgcagtga aatgtcagac tgtaaaacct tgtgtggaaa     7140

tgtttaactt ttattttttc atttaaattt gctgttctgg tattaccaaa ccacacattt     7200

gtaccgaatt ggcagtaaat gttagccatt tacagcaatg ccaaatatgg agaaacatca     7260

taataaaaaa atctgctttt tcatta                                          7286


<210>  434
<211>  2716
<212>  DNA
<213>  homo sapiens

<400>  434
ggctcaacga aggaagttca gggcgggacc agagattggc cattccgcta ctgcgcaaag       60

atggtggagg aggagaacat ccgcgtggtt cgttgtggcg gcagcgagtt gaactttagg      120

agagctgtgt tctctgcaga ttctaagtat atcttctgtg tctctggaga ctttgttaaa      180

gtttacagca cagttacaga agagtgtgta cacatactgc atggacacag aaatctggtg      240

actggaatcc agcttaaccc caacaaccat ctacagctgt attcttgttc ccttgatggc      300

acaattaaac tgtgggacta tatagatggc atcttaataa agactttcat agttggatgt      360

aaacttcatg ccctctttac tcttgcccaa gctgaggatt ctgtctttgt tatagtgaat      420

aaagaaaaac cagatatatt tcagctggtt tcagtgaaac tgccaaaatc ctcaagccag      480

gaagtagaag ccaaggagct gtcctttgtt ttggattaca taaaccagtc acccaagtgc      540

attgcctttg gaaacgaggg agtatatgtt gctgcagtac gggaatttta cttgtctgtt      600

tattttttca aaaagaaaac aacatcaagg tttactttat catcatcaag aaataagaag      660

catgctaaaa acaattttac atgtgtagca tgtcacccaa cggaagactg catcgcatct      720

ggtcacatgg atggcaaaat tcgtctttgg aggaattttt atgatgataa gaaatatacg      780

tacacatgtt tacattggca ccatgatatg gttatggatt tggctttttc agtgacaggc      840

accagtctgc tgagtggcgg tcgtgaatct gtacttgtag agtggcgcga tgcaacagag      900

aagaataagg agtttctccc gcgtttagga gctactattg aacatatctc agtctcgcct      960

gcaggagatt tattctgcac ttctcactct gataataaga taataattat tcaccgaaac     1020

cttgaagcat ccgcagtaat tcaaggccta gtgaaagata ggagtatctt cactggtttg     1080

atgattgatc caagaactaa agctttggtt ttgaatggaa aacctggcca cctgcagttt     1140

tattctctcc agagtgataa acagttatac aatttagata ttatacagca agaatatatt     1200

aatgattatg gtctgatcca aattgaacta acaaaggctg catttggctg ctttggtaac     1260

tggcttgcaa cagtggaaca gcggcaagaa aaggaaactg agcttgaatt gcaaatgaaa     1320

ctgtggatgt ataataagaa aacacaaggg tttattctta acactaaaat taacatgcca     1380

cacgaagact gcattacagc tctctgtttc tgtaatgcag aaaaatctga acagcccacc     1440

ttggttacag ctagcaaaga tggttacttc aaagtatgga tattaacaga tgactctgac     1500

atatacaaaa aagctgttgg ctggacctgt gactttgttg gtagttatca caagtatcaa     1560

gcaactaact gttgtttctc cgaagatggt tctttactag cagttagttt tgaggaaata     1620

gtcacaatat gggattctgt aacatgggaa cttaaatgta cattttgcca acgagctggg     1680

aaaataaggc acctttgctt tgggagattg acgtgttcaa agtatctact tggtgctact     1740

gaaaatggca ttctttgctg ttggaatctg ctgagctgtg cattggagtg gaatgcaaaa     1800

ttaaatgtta gagttatgga acccgatcct aattcagaga atattgctgc aatctctcag     1860

tcttcagtgg gttcagactt gtttgtattt aaacctagtg agccaaggcc attgtatatt     1920

caaaagggta tctccagaga gaaagtccag tggggagtgt ttgttccacg agatgtccct     1980

gaatccttca cctcagaagc ttaccagtgg ctaaatagat cccagtttta cttcctaaca     2040

aaatcacaga gtttattgac attcagtaca aagtctccag aagaaaaact cacaccaaca     2100

agcaaacagc tgctagcaga agaaagtctt cccacaaccc cattttattt catattggga     2160

aaacacaggc aacagcagga tgaaaaacta aacgaaactt tagagaatga gctggtacaa     2220

ctacccttaa cagaaaacat acccgcaatt agtgagcttc ttcacactcc agcccatgtc     2280

ctgccatctg ctgctttcct gtgctccatg tttgtaaatt cattgctgct gtctaaagag     2340

actaagagtg ctaaggaaat tcctgaagat gtagatatgg aagaagaaaa agaaagtgaa     2400

gattcagatg aagaaaatga ttttaccgaa aaagtccagg atacaagtaa cacaggttta     2460

ggagaagaca ttatacatca gttgtcaaaa tctgaagaaa aagaactgag aaaatttagg     2520

aaaatagact acagctggat agctgccctt taagccttgg agatggggag gatccttgga     2580

ctttgtgttt ttgattgtat gttgatattc taaaaacatc tattttaatg ttatttctgt     2640

tctaaaaata agataataaa tattaacaaa ctttgctttt ttaaaaaact gataatataa     2700

aaaaaaaaaa aaaaaa                                                     2716


<210>  435
<211>  10241
<212>  DNA
<213>  homo sapiens

<400>  435
ccggcgtcgg cggcgcgcgc gctccctcct ctcggagaga gggctgtggt aaaagccgtc       60

cggaaaatgg ccgccgccgc cgccgccgcg ccgagcggag gaggaggagg aggcgaggag      120

gagagactgc tccataaaaa tacagactca ccagttcctg ctttgatgtg acatgtgact      180

ccccagaata caccttgctt ctgtagacca gctccaacag gattccatgg tagctgggat      240

gttagggctc agggaagaaa agtcagaaga ccaggacctc cagggcctca aggacaaacc      300

cctcaagttt aaaaaggtga agaaagataa gaaagaagag aaagagggca agcatgagcc      360

cgtgcagcca tcagcccacc actctgctga gcccgcagag gcaggcaaag cagagacatc      420

agaagggtca ggctccgccc cggctgtgcc ggaagcttct gcctccccca aacagcggcg      480

ctccatcatc cgtgaccggg gacccatgta tgatgacccc accctgcctg aaggctggac      540

acggaagctt aagcaaagga aatctggccg ctctgctggg aagtatgatg tgtatttgat      600

caatccccag ggaaaagcct ttcgctctaa agtggagttg attgcgtact tcgaaaaggt      660

aggcgacaca tccctggacc ctaatgattt tgacttcacg gtaactggga gagggagccc      720

ctcccggcga gagcagaaac cacctaagaa gcccaaatct cccaaagctc caggaactgg      780

cagaggccgg ggacgcccca aagggagcgg caccacgaga cccaaggcgg ccacgtcaga      840

gggtgtgcag gtgaaaaggg tcctggagaa aagtcctggg aagctccttg tcaagatgcc      900

ttttcaaact tcgccagggg gcaaggctga ggggggtggg gccaccacat ccacccaggt      960

catggtgatc aaacgccccg gcaggaagcg aaaagctgag gccgaccctc aggccattcc     1020

caagaaacgg ggccgaaagc cggggagtgt ggtggcagcc gctgccgccg aggccaaaaa     1080

gaaagccgtg aaggagtctt ctatccgatc tgtgcaggag accgtactcc ccatcaagaa     1140

gcgcaagacc cgggagacgg tcagcatcga ggtcaaggaa gtggtgaagc ccctgctggt     1200

gtccaccctc ggtgagaaga gcgggaaagg actgaagacc tgtaagagcc ctgggcggaa     1260

aagcaaggag agcagcccca aggggcgcag cagcagcgcc tcctcacccc ccaagaagga     1320

gcaccaccac catcaccacc actcagagtc cccaaaggcc cccgtgccac tgctcccacc     1380

cctgccccca cctccacctg agcccgagag ctccgaggac cccaccagcc cccctgagcc     1440

ccaggacttg agcagcagcg tctgcaaaga ggagaagatg cccagaggag gctcactgga     1500

gagcgacggc tgccccaagg agccagctaa gactcagccc gcggttgcca ccgccgccac     1560

ggccgcagaa aagtacaaac accgagggga gggagagcgc aaagacattg tttcatcctc     1620

catgccaagg ccaaacagag aggagcctgt ggacagccgg acgcccgtga ccgagagagt     1680

tagctgactt tacacggagc ggattgcaaa gcaaaccaac aagaataaag gcagctgttg     1740

tctcttctcc ttatgggtag ggctctgaca aagcttcccg attaactgaa ataaaaaata     1800

tttttttttc tttcagtaaa cttagagttt cgtggcttca gggtgggagt agttggagca     1860

ttggggatgt ttttcttacc gacaagcaca gtcaggttga agacctaacc agggccagaa     1920

gtagctttgc acttttctaa actaggctcc ttcaacaagg cttgctgcag atactactga     1980

ccagacaagc tgttgaccag gcacctcccc tcccgcccaa acctttcccc catgtggtcg     2040

ttagagacag agcgacagag cagttgagag gacactcccg ttttcggtgc catcagtgcc     2100

ccgtctacag ctcccccagc tccccccacc tcccccactc ccaaccacgt tgggacaggg     2160

aggtgtgagg caggagagac agttggattc tttagagaag atggatatga ccagtggcta     2220

tggcctgtgc gatcccaccc gtggtggctc aagtctggcc ccacaccagc cccaatccaa     2280

aactggcaag gacgcttcac aggacaggaa agtggcacct gtctgctcca gctctggcat     2340

ggctaggagg ggggagtccc ttgaactact gggtgtagac tggcctgaac cacaggagag     2400

gatggcccag ggtgaggtgg catggtccat tctcaaggga cgtcctccaa cgggtggcgc     2460

tagaggccat ggaggcagta ggacaaggtg caggcaggct ggcctggggt caggccgggc     2520

agagcacagc ggggtgagag ggattcctaa tcactcagag cagtctgtga cttagtggac     2580

aggggagggg gcaaaggggg aggagaagaa aatgttcttc cagttacttt ccaattctcc     2640

tttagggaca gcttagaatt atttgcacta ttgagtcttc atgttcccac ttcaaaacaa     2700

acagatgctc tgagagcaaa ctggcttgaa ttggtgacat ttagtccctc aagccaccag     2760

atgtgacagt gttgagaact acctggattt gtatatatac ctgcgcttgt tttaaagtgg     2820

gctcagcaca tagggttccc acgaagctcc gaaactctaa gtgtttgctg caattttata     2880

aggacttcct gattggtttc tcttctcccc ttccatttct gccttttgtt catttcatcc     2940

tttcacttct ttcccttcct ccgtcctcct ccttcctagt tcatcccttc tcttccaggc     3000

agccgcggtg cccaaccaca cttgtcggct ccagtcccca gaactctgcc tgccctttgt     3060

cctcctgctg ccagtaccag ccccaccctg ttttgagccc tgaggaggcc ttgggctctg     3120

ctgagtccga cctggcctgt ctgtgaagag caagagagca gcaaggtctt gctctcctag     3180

gtagccccct cttccctggt aagaaaaagc aaaaggcatt tcccaccctg aacaacgagc     3240

cttttcaccc ttctactcta gagaagtgga ctggaggagc tgggcccgat ttggtagttg     3300

aggaaagcac agaggcctcc tgtggcctgc cagtcatcga gtggcccaac aggggctcca     3360

tgccagccga ccttgacctc actcagaagt ccagagtcta gcgtagtgca gcagggcagt     3420

agcggtacca atgcagaact cccaagaccc gagctgggac cagtacctgg gtccccagcc     3480

cttcctctgc tccccctttt ccctcggagt tcttcttgaa tggcaatgtt ttgcttttgc     3540

tcgatgcaga cagggggcca gaacaccaca catttcactg tctgtctggt ccatagctgt     3600

ggtgtagggg cttagaggca tgggcttgct gtgggttttt aattgatcag ttttcatgtg     3660

ggatcccatc tttttaacct ctgttcagga agtccttatc tagctgcata tcttcatcat     3720

attggtatat ccttttctgt gtttacagag atgtctctta tatctaaatc tgtccaactg     3780

agaagtacct tatcaaagta gcaaatgaga cagcagtctt atgcttccag aaacacccac     3840

aggcatgtcc catgtgagct gctgccatga actgtcaagt gtgtgttgtc ttgtgtattt     3900

cagttattgt ccctggcttc cttactatgg tgtaatcatg aaggagtgaa acatcataga     3960

aactgtctag cacttccttg ccagtcttta gtgatcagga accatagttg acagttccaa     4020

tcagtagctt aagaaaaaac cgtgtttgtc tcttctggaa tggttagaag tgagggagtt     4080

tgccccgttc tgtttgtaga gtctcatagt tggactttct agcatatatg tgtccatttc     4140

cttatgctgt aaaagcaagt cctgcaacca aactcccatc agcccaatcc ctgatccctg     4200

atcccttcca cctgctctgc tgatgacccc cccagcttca cttctgactc ttccccagga     4260

agggaagggg ggtcagaaga gagggtgagt cctccagaac tcttcctcca aggacagaag     4320

gctcctgccc ccatagtggc ctcgaactcc tggcactacc aaaggacact tatccacgag     4380

agcgcagcat ccgaccaggt tgtcactgag aagatgttta ttttggtcag ttgggttttt     4440

atgtattata cttagtcaaa tgtaatgtgg cttctggaat cattgtccag agctgcttcc     4500

ccgtcacctg ggcgtcatct ggtcctggta agaggagtgc gtggcccacc aggcccccct     4560

gtcacccatg acagttcatt cagggccgat ggggcagtcg tggttgggaa cacagcattt     4620

caagcgtcac tttatttcat tcgggcccca cctgcagctc cctcaaagag gcagttgccc     4680

agcctctttc ccttccagtt tattccagag ctgccagtgg ggcctgaggc tccttagggt     4740

tttctctcta tttccccctt tcttcctcat tccctcgtct ttcccaaagg catcacgagt     4800

cagtcgcctt tcagcaggca gccttggcgg tttatcgccc tggcaggcag gggccctgca     4860

gctctcatgc tgcccctgcc ttggggtcag gttgacagga ggttggaggg aaagccttaa     4920

gctgcaggat tctcaccagc tgtgtccggc ccagttttgg ggtgtgacct caatttcaat     4980

tttgtctgta cttgaacatt atgaagatgg gggcctcttt cagtgaattt gtgaacagca     5040

gaattgaccg acagctttcc agtacccatg gggctaggtc attaaggcca catccacagt     5100

ctcccccacc cttgttccag ttgttagtta ctacctcctc tcctgacaat actgtatgtc     5160

gtcgagctcc ccccaggtct acccctcccg gccctgcctg ctggtgggct tgtcatagcc     5220

agtgggattg ccggtcttga cagctcagtg agctggagat acttggtcac agccaggcgc     5280

tagcacagct cccttctgtt gatgctgtat tcccatatca aaagacacag gggacaccca     5340

gaaacgccac atcccccaat ccatcagtgc caaactagcc aacggcccca gcttctcagc     5400

tcgctggatg gcggaagctg ctactcgtga gcgccagtgc gggtgcagac aatcttctgt     5460

tgggtggcat cattccaggc ccgaagcatg aacagtgcac ctgggacagg gagcagcccc     5520

aaattgtcac ctgcttctct gcccagcttt tcattgctgt gacagtgatg gcgaaagagg     5580

gtaataacca gacacaaact gccaagttgg gtggagaaag gagtttcttt agctgacaga     5640

atctctgaat tttaaatcac ttagtaagcg gctcaagccc aggagggagc agagggatac     5700

gagcggagtc ccctgcgcgg gaccatctgg aattggttta gcccaagtgg agcctgacag     5760

ccagaactct gtgtcccccg tctaaccaca gctccttttc cagagcattc cagtcaggct     5820

ctctgggctg actgggccag gggaggttac aggtaccagt tctttaagaa gatctttggg     5880

catatacatt tttagcctgt gtcattgccc caaatggatt cctgtttcaa gttcacacct     5940

gcagattcta ggacctgtgt cctagacttc agggagtcag ctgtttctag agttcctacc     6000

atggagtggg tctggaggac ctgcccggtg ggggggcaga gccctgctcc ctccgggtct     6060

tcctactctt ctctctgctc tgacgggatt tgttgattct ctccattttg gtgtctttct     6120

cttttagata ttgtatcaat ctttagaaaa ggcatagtct acttgttata aatcgttagg     6180

atactgcctc ccccagggtc taaaattaca tattagaggg gaaaagctga acactgaagt     6240

cagttctcaa caatttagaa ggaaaaccta gaaaacattt ggcagaaaat tacatttcga     6300

tgtttttgaa tgaatacgag caagctttta caacagtgct gatctaaaaa tacttagcac     6360

ttggcctgag atgcctggtg agcattacag gcaaggggaa tctggaggta gccgacctga     6420

ggacatggct tctgaacctg tcttttggga gtggtatgga aggtggagcg ttcaccagtg     6480

acctggaagg cccagcacca ccctccttcc cactcttctc atcttgacag agcctgcccc     6540

agcgctgacg tgtcaggaaa acacccaggg aactaggaag gcacttctgc ctgaggggca     6600

gcctgccttg cccactcctg ctctgctcgc ctcggatcag ctgagccttc tgagctggcc     6660

tctcactgcc tccccaaggc cccctgcctg ccctgtcagg aggcagaagg aagcaggtgt     6720

gagggcagtg caaggaggga gcacaacccc cagctcccgc tccgggctcc gacttgtgca     6780

caggcagagc ccagaccctg gaggaaatcc tacctttgaa ttcaagaaca tttggggaat     6840

ttggaaatct ctttgccccc aaacccccat tctgtcctac ctttaatcag gtcctgctca     6900

gcagtgagag cagatgaggt gaaaaggcca agaggtttgg ctcctgccca ctgatagccc     6960

ctctccccgc agtgtttgtg tgtcaagtgg caaagctgtt cttcctggtg accctgatta     7020

tatccagtaa cacatagact gtgcgcatag gcctgctttg tctcctctat cctgggcttt     7080

tgttttgctt tttagttttg cttttagttt ttctgtccct tttatttaac gcaccgacta     7140

gacacacaaa gcagttgaat ttttatatat atatctgtat attgcacaat tataaactca     7200

ttttgcttgt ggctccacac acacaaaaaa agacctgtta aaattatacc tgttgcttaa     7260

ttacaatatt tctgataacc atagcatagg acaagggaaa ataaaaaaag aaaaaaaaga     7320

aaaaaaaacg acaaatctgt ctgctggtca cttcttctgt ccaagcagat tcgtggtctt     7380

ttcctcgctt ctttcaaggg ctttcctgtg ccaggtgaag gaggctccag gcagcaccca     7440

ggttttgcac tcttgtttct cccgtgcttg tgaaagaggt cccaaggttc tgggtgcagg     7500

agcgctccct tgacctgctg aagtccggaa cgtagtcggc acagcctggt cgccttccac     7560

ctctgggagc tggagtccac tggggtggcc tgactccccc agtccccttc ccgtgacctg     7620

gtcagggtga gcccatgtgg agtcagcctc gcaggcctcc ctgccagtag ggtccgagtg     7680

tgtttcatcc ttcccactct gtcgagcctg ggggctggag cggagacggg aggcctggcc     7740

tgtctcggaa cctgtgagct gcaccaggta gaacgccagg gaccccagaa tcatgtgcgt     7800

cagtccaagg ggtcccctcc aggagtagtg aagactccag aaatgtccct ttcttctccc     7860

ccatcctacg agtaattgca tttgcttttg taattcttaa tgagcaatat ctgctagaga     7920

gtttagctgt aacagttctt tttgatcatc tttttttaat aattagaaac accaaaaaaa     7980

tccagaaact tgttcttcca aagcagagag cattataatc accagggcca aaagcttccc     8040

tccctgctgt cattgcttct tctgaggcct gaatccaaaa gaaaaacagc cataggccct     8100

ttcagtggcc gggctacccg tgagcccttc ggaggaccag ggctggggca gcctctgggc     8160

ccacatccgg ggccagctcc ggcgtgtgtt cagtgttagc agtgggtcat gatgctcttt     8220

cccacccagc ctgggatagg ggcagaggag gcgaggaggc cgttgccgct gatgtttggc     8280

cgtgaacagg tgggtgtctg cgtgcgtcca cgtgcgtgtt ttctgactga catgaaatcg     8340

acgcccgagt tagcctcacc cggtgacctc tagccctgcc cggatggagc ggggcccacc     8400

cggttcagtg tttctgggga gctggacagt ggagtgcaaa aggcttgcag aacttgaagc     8460

ctgctccttc ccttgctacc acggcctcct ttccgtttga tttgtcactg cttcaatcaa     8520

taacagccgc tccagagtca gtagtcaatg aatatatgac caaatatcac caggactgtt     8580

actcaatgtg tgccgagccc ttgcccatgc tgggctcccg tgtatctgga cactgtaacg     8640

tgtgctgtgt ttgctcccct tccccttcct tctttgccct ttacttgtct ttctggggtt     8700

tttctgtttg ggtttggttt ggtttttatt tctccttttg tgttccaaac atgaggttct     8760

ctctactggt cctcttaact gtggtgttga ggcttatatt tgtgtaattt ttggtgggtg     8820

aaaggaattt tgctaagtaa atctcttctg tgtttgaact gaagtctgta ttgtaactat     8880

gtttaaagta attgttccag agacaaatat ttctagacac tttttcttta caaacaaaag     8940

cattcggagg gagggggatg gtgactgaga tgagagggga gagctgaaca gatgacccct     9000

gcccagatca gccagaagcc acccaaagca gtggagccca ggagtcccac tccaagccag     9060

caagccgaat agctgatgtg ttgccacttt ccaagtcact gcaaaaccag gttttgttcc     9120

gcccagtgga ttcttgtttt gcttcccctc cccccgagat tattaccacc atcccgtgct     9180

tttaaggaaa ggcaagattg atgtttcctt gaggggagcc aggaggggat gtgtgtgtgc     9240

agagctgaag agctggggag aatggggctg ggcccaccca agcaggaggc tgggacgctc     9300

tgctgtgggc acaggtcagg ctaatgttgg cagatgcagc tcttcctgga caggccaggt     9360

ggtgggcatt ctctctccaa ggtgtgcccc gtgggcatta ctgtttaaga cacttccgtc     9420

acatcccacc ccatcctcca gggctcaaca ctgtgacatc tctattcccc accctcccct     9480

tcccagggca ataaaatgac catggagggg gcttgcactc tcttggctgt cacccgatcg     9540

ccagcaaaac ttagatgtga gaaaacccct tcccattcca tggcgaaaac atctccttag     9600

aaaagccatt accctcatta ggcatggttt tgggctccca aaacacctga cagcccctcc     9660

ctcctctgag aggcggagag tgctgactgt agtgaccatt gcatgccggg tgcagcatct     9720

ggaagagcta ggcagggtgt ctgccccctc ctgagttgaa gtcatgctcc cctgtgccag     9780

cccagaggcc gagagctatg gacagcattg ccagtaacac aggccaccct gtgcagaagg     9840

gagctggctc cagcctggaa acctgtctga ggttgggaga ggtgcacttg gggcacaggg     9900

agaggccggg acacacttag ctggagatgt ctctaaaagc cctgtatcgt attcaccttc     9960

agtttttgtg ttttgggaca attactttag aaaataagta ggtcgtttta aaaacaaaaa    10020

ttattgattg cttttttgta gtgttcagaa aaaaggttct ttgtgtatag ccaaatgact    10080

gaaagcactg atatatttaa aaacaaaagg caatttatta aggaaatttg taccatttca    10140

gtaaacctgt ctgaatgtac ctgtatacgt ttcaaaaaca cccccccccc actgaatccc    10200

tgtaacctat ttattatata aagagtttgc cttataaatt t                        10241


<210>  436
<211>  2287
<212>  DNA
<213>  homo sapiens

<400>  436
ttctcgccac gcacctgcgt cagctcgctc tgcgcgtgcg ccggtggcgg gactctgggg       60

aaaatggctg cgtcttcgag tggtgagaag gagaaggagc ggctgggagg cggtttggga      120

gtggcgggtg gtaacagcac acgagagcgg ctgctgtctg cgcttgagga cttggaggtc      180

ctgtctaggg aacttataga aatgctggca atttcaagaa accaaaagtt gttacaggct      240

ggagaggaaa accaggtcct ggagttgtta attcaccgag atggggaatt tcaagaacta      300

atgaaattgg cacttaatca gggaaaaatt catcatgaaa tgcaagtttt agaaaaagaa      360

gtagagaaga gagacagtga tattcagcag ctacaaaaac agctaaagga agcagaacaa      420

atactggcaa cagctgttta ccaagcgaag gagaaactca agtcaataga aaaagcaaga      480

aaaggtgcta tctcctctga agaaataatt aagtatgcac ataggatcag tgcaagtaat      540

gctgtatgtg ctccactgac ctgggttcca ggggaccccc ggagacccta cccaactgat      600

ttagagatga gaagtgggtt actgggtcag atgaacaatc cttccactaa tggcgtgaat      660

ggccatttac caggagatgc acttgcagca ggaagattgc cagatgtcct tgctccacag      720

tatccatggc agtcaaatga catgtcgatg aatatgttac caccaaatca tagtagtgac      780

tttttgttgg aacctcctgg gcataataaa gaaaatgaag atgatgtaga gattatgtca      840

acggactcct caagcagtag tagtgagtct gattgaaaaa ccttaaaaga caatatacag      900

aattgaatac tgtagaattc tgtttcttta acagtagcag ggaaatgtaa actacaggtg      960

acaaaaaata cccaggtaaa cactggcttt ggtagaattg tgcagtcatt aaaagtcaaa     1020

attttttgac tttcttttta aagccaaaga ccatagtttt agttttaagc cactaggtag     1080

atatttaggg gaatagtcaa aatttactgt tgaaaaagca gttgctatgt gctttcttac     1140

cctgttctgt tccagttttg ctggatttgt acatagccat tctagaaata gagttgaggg     1200

aaattatcca tatacatatc actaataggc ttcttggaat tatttagaaa agcattttta     1260

aactggcagt ggatgactga ataggcatca tatttctttt tgtgtgtcat ttaaaagtaa     1320

caaaaactgc catttgacag taaaggctct tggcttctgt tggaggcatg ggaaattgtc     1380

tcaatttgta cagtttgtaa ttgtaatttt tgtaaataaa tttgtttgta cattgtatgc     1440

ttttttttta gtttaaatat actgtcagtg taggtaggaa attatttctg taaatccagt     1500

tgcattttat aatacttgag tgactaactg aattgaaacc tattacaatt aatagggttc     1560

tcaaaggcct attcctatta gaagaaataa ttttttttaa taattgaaaa aatttaccac     1620

agccttgtct gattttaaga atagattgtg tgaagattta gaatggaaag caaccatttc     1680

ttcccttcac cttcctcttc ttacagttcc ccaggagtca tttttaacca cttttaattt     1740

ctgttggtaa cctctgtgtt taggtaatat gcttatacaa ctatttcttg atgtatcagt     1800

tttagacaat gtatcttctg atttcaaagg taatacaaca tttaatgtga aacatttagt     1860

gaatacagta aaggagaaaa taaaattgtt agcattctac ccagagataa tatcaattca     1920

tattgtagtg tagatttttt taaagttcac atacactttt ttgtaaaatg agaataatgt     1980

ttatttcctg agatactgct gtatttttta attgctaatc tgtattcttc aaatgaactg     2040

agaattccat ttttccatca ttttttcctt ttgattattt tcgatctcta gaaaaattgg     2100

aaaataggag attaatctta tattttcacc atctagaatt aaggacatac aatgtttgaa     2160

tgtctttccc tccagggtta tttttaggaa tggactaaca caatatctaa ttttaacctt     2220

gccttgtccg tatactagga atattgatcc atgtgtatac attcttgaaa gatttacttt     2280

aatggct                                                               2287


<210>  437
<211>  1625
<212>  DNA
<213>  homo sapiens

<400>  437
gttgccgggc tacgggagag cgcggagccc tgcgctggga ggtgcacggt gtgcacgctg       60

gactggaccc ccatgcaacc ccgcgccctg cgccttaacc aggactgctc cgcgcgcccc      120

tgagcctcgg gctccggccc ggacctgcag cctcccaggt ggctgggaag aactctccaa      180

caataaatac atttgataag aaagatggct ttaaaagtgc tactagaaca agagaaaacg      240

tttttcactc ttttagtatt actaggctat ttgtcatgta aagtgacttg tgaatcagga      300

gactgtagac agcaagaatt cagggatcgg tctggaaact gtgttccctg caaccagtgt      360

gggccaggca tggagttgtc taaggaatgt ggcttcggct atggggagga tgcacagtgt      420

gtgacgtgcc ggctgcacag gttcaaggag gactggggct tccagaaatg caagccctgt      480

ctggactgcg cagtggtgaa ccgctttcag aaggcaaatt gttcagccac cagtgatgcc      540

atctgcgggg actgcttgcc aggattttat aggaagacga aacttgtcgg ctttcaagac      600

atggagtgtg tgccttgtgg agaccctcct cctccttacg aaccgcactg tgccagcaag      660

gtcaacctcg tgaagatcgc gtccacggcc tccagcccac gggacacggc gctggctgcc      720

gttatctgca gcgctctggc caccgtcctg ctggccctgc tcatcctctg tgtcatctat      780

tgtaagagac agtttatgga gaagaaaccc agctggtctc tgcggtcaca ggacattcag      840

tacaacggct ctgagctgtc gtgttttgac agacctcagc tccacgaata tgcccacaga      900

gcctgctgcc agtgccgccg tgactcagtg cagacctgcg ggccggtgcg cttgctccca      960

tccatgtgct gtgaggaggc ctgcagcccc aacccggcga ctcttggttg tggggtgcat     1020

tctgcagcca gtcttcaggc aagaaacgca ggcccagccg gggagatggt gccgactttc     1080

ttcggatccc tcacgcagtc catctgtggc gagttttcag atgcctggcc tctgatgcag     1140

aatcccatgg gtggtgacaa catctctttt tgtgactctt atcctgaact cactggagaa     1200

gacattcatt ctctcaatcc agaacttgaa agctcaacgt ctttggattc aaatagcagt     1260

caagatttgg ttggtggggc tgttccagtc cagtctcatt ctgaaaactt tacagcagct     1320

actgatttat ctagatataa caacacactg gtagaatcag catcaactca ggatgcacta     1380

actatgagaa gccagctaga tcaggagagt ggtgctgtca tccacccagc cactcagacg     1440

tccctccagg taaggcagcg actgggttcc ctgtgaacac agcactgact tacagtagat     1500

cagaactctg ttcccagcat aagatttggg ggaacctgat gagttttttt tttgcatctt     1560

taataatttc ttgtatgttg tagagtatgt tttaaaataa atttcaagta tttttttaaa     1620

aaact                                                                 1625


<210>  438
<211>  3968
<212>  DNA
<213>  homo sapiens

<400>  438
gtcgcgggca gctggcgccg cgcggtcctg ctctgccggt cgcacggacg caccggcggg       60

ccgccggccg gagggacggg gcgggagctg ggcccgcgga cagcgagccg gagcgggagc      120

cgcgcgtagc gagccgggct ccggcgctcg ccagtctccc gagcggcgcc cgcctcccgc      180

cggtgcccgc gccgggccgt ggggggcagc atgcccgcgc gcgctgcctg aggacgccgc      240

ggcccccgcc cccgccatgg gcgcccctgc ctgcgccctc gcgctctgcg tggccgtggc      300

catcgtggcc ggcgcctcct cggagtcctt ggggacggag cagcgcgtcg tggggcgagc      360

ggcagaagtc ccgggcccag agcccggcca gcaggagcag ttggtcttcg gcagcgggga      420

tgctgtggag ctgagctgtc ccccgcccgg gggtggtccc atggggccca ctgtctgggt      480

caaggatggc acagggctgg tgccctcgga gcgtgtcctg gtggggcccc agcggctgca      540

ggtgctgaat gcctcccacg aggactccgg ggcctacagc tgccggcagc ggctcacgca      600

gcgcgtactg tgccacttca gtgtgcgggt gacagacgct ccatcctcgg gagatgacga      660

agacggggag gacgaggctg aggacacagg tgtggacaca ggggcccctt actggacacg      720

gcccgagcgg atggacaaga agctgctggc cgtgccggcc gccaacaccg tccgcttccg      780

ctgcccagcc gctggcaacc ccactccctc catctcctgg ctgaagaacg gcagggagtt      840

ccgcggcgag caccgcattg gaggcatcaa gctgcggcat cagcagtgga gcctggtcat      900

ggaaagcgtg gtgccctcgg accgcggcaa ctacacctgc gtcgtggaga acaagtttgg      960

cagcatccgg cagacgtaca cgctggacgt gctggagcgc tccccgcacc ggcccatcct     1020

gcaggcgggg ctgccggcca accagacggc ggtgctgggc agcgacgtgg agttccactg     1080

caaggtgtac agtgacgcac agccccacat ccagtggctc aagcacgtgg aggtgaatgg     1140

cagcaaggtg ggcccggacg gcacacccta cgttaccgtg ctcaaggtgt ccctggagtc     1200

caacgcgtcc atgagctcca acacaccact ggtgcgcatc gcaaggctgt cctcagggga     1260

gggccccacg ctggccaatg tctccgagct cgagctgcct gccgacccca aatgggagct     1320

gtctcgggcc cggctgaccc tgggcaagcc ccttggggag ggctgcttcg gccaggtggt     1380

catggcggag gccatcggca ttgacaagga ccgggccgcc aagcctgtca ccgtagccgt     1440

gaagatgctg aaagacgatg ccactgacaa ggacctgtcg gacctggtgt ctgagatgga     1500

gatgatgaag atgatcggga aacacaaaaa catcatcaac ctgctgggcg cctgcacgca     1560

gggcgggccc ctgtacgtgc tggtggagta cgcggccaag ggtaacctgc gggagtttct     1620

gcgggcgcgg cggcccccgg gcctggacta ctccttcgac acctgcaagc cgcccgagga     1680

gcagctcacc ttcaaggacc tggtgtcctg tgcctaccag gtggcccggg gcatggagta     1740

cttggcctcc cagaagtgca tccacaggga cctggctgcc cgcaatgtgc tggtgaccga     1800

ggacaacgtg atgaagatcg cagacttcgg gctggcccgg gacgtgcaca acctcgacta     1860

ctacaagaag acaaccaacg gccggctgcc cgtgaagtgg atggcgcctg aggccttgtt     1920

tgaccgagtc tacactcacc agagtgacgt ctggtccttt ggggtcctgc tctgggagat     1980

cttcacgctg gggggctccc cgtaccccgg catccctgtg gaggagctct tcaagctgct     2040

gaaggagggc caccgcatgg acaagcccgc caactgcaca cacgacctgt acatgatcat     2100

gcgggagtgc tggcatgccg cgccctccca gaggcccacc ttcaagcagc tggtggagga     2160

cctggaccgt gtccttaccg tgacgtccac cgacgagtac ctggacctgt cggcgccttt     2220

cgagcagtac tccccgggtg gccaggacac ccccagctcc agctcctcag gggacgactc     2280

cgtgtttgcc cacgacctgc tgcccccggc cccacccagc agtgggggct cgcggacgtg     2340

aagggccact ggtccccaac aatgtgaggg gtccctagca gcccaccctg ctgctggtgc     2400

acagccactc cccggcatga gactcagtgc agatggagag acagctacac agagctttgg     2460

tctgtgtgtg tgtgtgtgcg tgtgtgtgtg tgtgtgtgca catccgcgtg tgcctgtgtg     2520

cgtgcgcatc ttgcctccag gtgcagaggt accctgggtg tccccgctgc tgtgcaacgg     2580

tctcctgact ggtgctgcag caccgagggg cctttgttct ggggggaccc agtgcagaat     2640

gtaagtgggc ccacccggtg ggacccccgt ggggcaggga gctgggcccg acatggctcc     2700

ggcctctgcc tttgcaccac gggacatcac agggtgggcc tcggcccctc ccacacccaa     2760

agctgagcct gcagggaagc cccacatgtc cagcaccttg tgcctggggt gttagtggca     2820

ccgcctcccc acctccaggc tttcccactt cccaccctgc ccctcagaga ctgaaattac     2880

gggtacctga agatgggagc ctttaccttt tatgcaaaag gtttattccg gaaactagtg     2940

tacatttcta taaatagatg ctgtgtatat ggtatatata catatatata tataacatat     3000

atggaagagg aaaaggctgg tacaacggag gcctgcgacc ctgggggcac aggaggcagg     3060

catggccctg ggcggggcgt gggggggcgt ggagggaggc cccagggggt ctcacccatg     3120

caagcagagg accagggcct tttctggcac cgcagttttg ttttaaaact ggacctgtat     3180

atttgtaaag ctatttatgg gcccctggca ctcttgttcc cacaccccaa cacttccagc     3240

atttagctgg ccacatggcg gagagtttta atttttaact tattgacaac cgagaaggtt     3300

tatcccgccg atagagggac ggccaagaat gtacgtccag cctgccccgg agctggagga     3360

tcccctccaa gcctaaaagg ttgttaatag ttggaggtga ttccagtgaa gatattttat     3420

ttcctttgtc ctttttcagg agaattagat ttctatagga tttttcttta ggagatttat     3480

tttttggact tcaaagcaag ctggtatttt catacaaatt cttctaattg ctgtgtgtcc     3540

caggcaggga gacggtttcc agggaggggc cggccctgtg tgcaggttcc gatgttatta     3600

gatgttacaa gtttatatat atctatatat ataatttatt gagtttttac aagatgtatt     3660

tgttgtagac ttaacacttc ttacgcaatg cttctagagt tttatagcct ggactgctac     3720

ctttcaaagc ttggagggaa gccgtgaatt cagttggttc gttctgtact gttactgggc     3780

cctgagtctg ggcagctgtc ccttgcttgc ctgcagggcc atggctcagg gtggtctctt     3840

cttggggccc agtgcatggt ggccagaggt gtcacccaaa ccggcaggtg cgattttgtt     3900

aacccagcga cgaactttcc gaaaaataaa gacacctggt tgctaacctg gaaaaaaaaa     3960

aaaaaaaa                                                              3968


<210>  439
<211>  4310
<212>  DNA
<213>  homo sapiens

<400>  439
gtcgcgggca gctggcgccg cgcggtcctg ctctgccggt cgcacggacg caccggcggg       60

ccgccggccg gagggacggg gcgggagctg ggcccgcgga cagcgagccg gagcgggagc      120

cgcgcgtagc gagccgggct ccggcgctcg ccagtctccc gagcggcgcc cgcctcccgc      180

cggtgcccgc gccgggccgt ggggggcagc atgcccgcgc gcgctgcctg aggacgccgc      240

ggcccccgcc cccgccatgg gcgcccctgc ctgcgccctc gcgctctgcg tggccgtggc      300

catcgtggcc ggcgcctcct cggagtcctt ggggacggag cagcgcgtcg tggggcgagc      360

ggcagaagtc ccgggcccag agcccggcca gcaggagcag ttggtcttcg gcagcgggga      420

tgctgtggag ctgagctgtc ccccgcccgg gggtggtccc atggggccca ctgtctgggt      480

caaggatggc acagggctgg tgccctcgga gcgtgtcctg gtggggcccc agcggctgca      540

ggtgctgaat gcctcccacg aggactccgg ggcctacagc tgccggcagc ggctcacgca      600

gcgcgtactg tgccacttca gtgtgcgggt gacagacgct ccatcctcgg gagatgacga      660

agacggggag gacgaggctg aggacacagg tgtggacaca ggggcccctt actggacacg      720

gcccgagcgg atggacaaga agctgctggc cgtgccggcc gccaacaccg tccgcttccg      780

ctgcccagcc gctggcaacc ccactccctc catctcctgg ctgaagaacg gcagggagtt      840

ccgcggcgag caccgcattg gaggcatcaa gctgcggcat cagcagtgga gcctggtcat      900

ggaaagcgtg gtgccctcgg accgcggcaa ctacacctgc gtcgtggaga acaagtttgg      960

cagcatccgg cagacgtaca cgctggacgt gctggagcgc tccccgcacc ggcccatcct     1020

gcaggcgggg ctgccggcca accagacggc ggtgctgggc agcgacgtgg agttccactg     1080

caaggtgtac agtgacgcac agccccacat ccagtggctc aagcacgtgg aggtgaatgg     1140

cagcaaggtg ggcccggacg gcacacccta cgttaccgtg ctcaagtcct ggatcagtga     1200

gagtgtggag gccgacgtgc gcctccgcct ggccaatgtg tcggagcggg acgggggcga     1260

gtacctctgt cgagccacca atttcatagg cgtggccgag aaggcctttt ggctgagcgt     1320

tcacgggccc cgagcagccg aggaggagct ggtggaggct gacgaggcgg gcagtgtgta     1380

tgcaggcatc ctcagctacg gggtgggctt cttcctgttc atcctggtgg tggcggctgt     1440

gacgctctgc cgcctgcgca gcccccccaa gaaaggcctg ggctccccca ccgtgcacaa     1500

gatctcccgc ttcccgctca agcgacaggt gtccctggag tccaacgcgt ccatgagctc     1560

caacacacca ctggtgcgca tcgcaaggct gtcctcaggg gagggcccca cgctggccaa     1620

tgtctccgag ctcgagctgc ctgccgaccc caaatgggag ctgtctcggg cccggctgac     1680

cctgggcaag ccccttgggg agggctgctt cggccaggtg gtcatggcgg aggccatcgg     1740

cattgacaag gaccgggccg ccaagcctgt caccgtagcc gtgaagatgc tgaaagacga     1800

tgccactgac aaggacctgt cggacctggt gtctgagatg gagatgatga agatgatcgg     1860

gaaacacaaa aacatcatca acctgctggg cgcctgcacg cagggcgggc ccctgtacgt     1920

gctggtggag tacgcggcca agggtaacct gcgggagttt ctgcgggcgc ggcggccccc     1980

gggcctggac tactccttcg acacctgcaa gccgcccgag gagcagctca ccttcaagga     2040

cctggtgtcc tgtgcctacc aggtggcccg gggcatggag tacttggcct cccagaagtg     2100

catccacagg gacctggctg cccgcaatgt gctggtgacc gaggacaacg tgatgaagat     2160

cgcagacttc gggctggccc gggacgtgca caacctcgac tactacaaga agacaaccaa     2220

cggccggctg cccgtgaagt ggatggcgcc tgaggccttg tttgaccgag tctacactca     2280

ccagagtgac gtctggtcct ttggggtcct gctctgggag atcttcacgc tggggggctc     2340

cccgtacccc ggcatccctg tggaggagct cttcaagctg ctgaaggagg gccaccgcat     2400

ggacaagccc gccaactgca cacacgacct gtacatgatc atgcgggagt gctggcatgc     2460

cgcgccctcc cagaggccca ccttcaagca gctggtggag gacctggacc gtgtccttac     2520

cgtgacgtcc accgacgagt acctggacct gtcggcgcct ttcgagcagt actccccggg     2580

tggccaggac acccccagct ccagctcctc aggggacgac tccgtgtttg cccacgacct     2640

gctgcccccg gccccaccca gcagtggggg ctcgcggacg tgaagggcca ctggtcccca     2700

acaatgtgag gggtccctag cagcccaccc tgctgctggt gcacagccac tccccggcat     2760

gagactcagt gcagatggag agacagctac acagagcttt ggtctgtgtg tgtgtgtgtg     2820

cgtgtgtgtg tgtgtgtgtg cacatccgcg tgtgcctgtg tgcgtgcgca tcttgcctcc     2880

aggtgcagag gtaccctggg tgtccccgct gctgtgcaac ggtctcctga ctggtgctgc     2940

agcaccgagg ggcctttgtt ctggggggac ccagtgcaga atgtaagtgg gcccacccgg     3000

tgggaccccc gtggggcagg gagctgggcc cgacatggct ccggcctctg cctttgcacc     3060

acgggacatc acagggtggg cctcggcccc tcccacaccc aaagctgagc ctgcagggaa     3120

gccccacatg tccagcacct tgtgcctggg gtgttagtgg caccgcctcc ccacctccag     3180

gctttcccac ttcccaccct gcccctcaga gactgaaatt acgggtacct gaagatggga     3240

gcctttacct tttatgcaaa aggtttattc cggaaactag tgtacatttc tataaataga     3300

tgctgtgtat atggtatata tacatatata tatataacat atatggaaga ggaaaaggct     3360

ggtacaacgg aggcctgcga ccctgggggc acaggaggca ggcatggccc tgggcggggc     3420

gtgggggggc gtggagggag gccccagggg gtctcaccca tgcaagcaga ggaccagggc     3480

cttttctggc accgcagttt tgttttaaaa ctggacctgt atatttgtaa agctatttat     3540

gggcccctgg cactcttgtt cccacacccc aacacttcca gcatttagct ggccacatgg     3600

cggagagttt taatttttaa cttattgaca accgagaagg tttatcccgc cgatagaggg     3660

acggccaaga atgtacgtcc agcctgcccc ggagctggag gatcccctcc aagcctaaaa     3720

ggttgttaat agttggaggt gattccagtg aagatatttt atttcctttg tcctttttca     3780

ggagaattag atttctatag gatttttctt taggagattt attttttgga cttcaaagca     3840

agctggtatt ttcatacaaa ttcttctaat tgctgtgtgt cccaggcagg gagacggttt     3900

ccagggaggg gccggccctg tgtgcaggtt ccgatgttat tagatgttac aagtttatat     3960

atatctatat atataattta ttgagttttt acaagatgta tttgttgtag acttaacact     4020

tcttacgcaa tgcttctaga gttttatagc ctggactgct acctttcaaa gcttggaggg     4080

aagccgtgaa ttcagttggt tcgttctgta ctgttactgg gccctgagtc tgggcagctg     4140

tcccttgctt gcctgcaggg ccatggctca gggtggtctc ttcttggggc ccagtgcatg     4200

gtggccagag gtgtcaccca aaccggcagg tgcgattttg ttaacccagc gacgaacttt     4260

ccgaaaaata aagacacctg gttgctaacc tggaaaaaaa aaaaaaaaaa                4310


<210>  440
<211>  4277
<212>  DNA
<213>  homo sapiens

<400>  440
ggagttcgcg cgacgaccgc ggggtcggcg ggcggggcga ggccctggac ggcggcggca       60

gtggggctcc tccttctgtt tcccagaccg agagccgcgc cggcaccatg tcagcttacc      120

ctaaaagcta caatccgttc gacgacgacg gggaggacga aggcgcccgg ccggcccctt      180

ggagggacgc ccgagacctc cccgacgggc ccgacgcgcc cgcggacagg cagcagtact      240

tgcggcagga ggtcctccgc agggctgagg ccacggccgc cagcaccagc aggtccctgg      300

ccctcatgta cgagtccgag aaggttgggg tcgcctcttc cgaggagctc gcccgtcagc      360

gaggagtcct ggagcgcaca gagaagatgg tggacaagat ggaccaagat ttgaagatca      420

gccagaaaca catcaatagc attaagagcg tgtttggggg gctggtcaat tacttcaaat      480

ccaaaccagt agagacccca cctgaacaga atggcaccct cacctcccag cccaacaaca      540

gattgaaaga agctataagt acaagtaaag aacaggaagc aaagtaccag gccagccacc      600

caaaccttag aaagctggat gatacagacc ctgtccccag aggggctggt tctgccatga      660

gtactgatgc ttacccaaag aacccacacc ttcgagccta tcaccagaag atcgacagca      720

acctagatga gctgtccatg ggactgggtc gtctgaagga catagccctg gggatgcaga      780

cagaaattga ggagcaagat gacattcttg accggctgac aaccaaagtg gacaagttag      840

atgtcaacat aaaaagcaca gaaagaaaag ttcgacaact ctgaagacag acggatttcc      900

actctattgt gatgaaaaga tttgaaagat ctttttttga acttccaaga aatttcattt      960

actattttag tatgtaaatt aatgtgtgtt tgcaaatgtt ataatagagt aggtcttaag     1020

acatttttgc tgttataagg aagtgtttgt cccacatttt cctagggtta acacctcacc     1080

aagttcttcc agcaaaatgc ttattagagt ttttgtctga gcacagtagc ctggccctgc     1140

atatcttggg cgtttgatta ccatgctgga ataagaagag ttgcatttct cattttaatg     1200

agcatatgga aagatgggaa cagaatttca gtcttgcagc catgagcctc tatttctcat     1260

tcctaagcct taccatgagt cagagtgtta agggggcctg tgaaccagtc gtttggtgga     1320

ggagggtcct tcccacacct ttgtttagga gtcatcattc acacacacac acacacacac     1380

acacacacac acacacacac acactctctg agcacattat ctgtgattct ttcatcctcc     1440

cagaaaggat cagtgttaga atgggaaata gagtgtgcca tcttgctctt ttgttggcag     1500

atgtccccgc ttccctccag ccccccatcc ttggcatgta tattagtagg agggcttcac     1560

accagcactg ctcactgcga ctcctggaaa tgtgtgggga attgggtgag cccctcttcc     1620

ccacgtgctc ccatctgtaa ctctccatct gtgatttgca acaggtcttc cactggctcg     1680

aggctgcgag gctgaccgac aggggcgccc aatagagttt gtgggaatgg agtattgcac     1740

agatgcagct gcacaatggt cttcctccac ccctctggga atcaccatta ggcaggcctc     1800

agtagggcaa aatgtttatt tggtaccggg ggtctcctga cctgtctagc attcccaccc     1860

actcttctgc acttcttgca aggtaacttg aatcatcact tatttctctg ccacctggtt     1920

ttaggactgg cactctataa atgacgctga ctttgtatag aaggattttg ctaagggggc     1980

aaaaagccca gataccattt taactggccc agttcatttt ctcctttcat tttacaaaag     2040

aaatcatgca gaagcatcaa ttaaaactga tttatttatg ttggtacatc caacaaaata     2100

gttggagcca caaggccctt gtctttttaa aaaaacaaaa tattttgaag atggtgaaag     2160

tgactgattt taataatgag ataggtcact taaaataaca gtgcctttga ccttaaaaca     2220

tggcactggc ccatgtgacc tttgccattt cccagtactt ccctttacag tctgcagcct     2280

ataaacagtg gtgtctcaaa gcaaaggaaa cctccacaag tgctgcaaca gtgcattagt     2340

ttttatgtag caatttgttt ataaaaattc ccatcccata atgcatgacc ttcctaaaaa     2400

tatccacagc ctccataggc aaggtgagct ttctgtgcta cccacttgtt agattccagc     2460

cacctcaggg attctgatcc atgtcattaa cgaccatccc agggtgtgag ggcctgatta     2520

aagcttatcg aactagacat ttgtttatta gatgagctcg gcattattat tttctcaata     2580

actggtagaa gggaaatttt aaacataaca ctcaacccaa acaaaactac ttcgtgaggc     2640

tttcagcaaa aaggctgctt aaaagcatga acccgggatg cagagcagct tttgtgcacg     2700

gttccactta ctgtaattgt ttctggttct ttcctctaac accttccatg tatgtcaact     2760

ttttatcacc gtcaggcata gactcgtgga gattagtcat tatagctcag acctaagcta     2820

attatttaaa ataaatacat gtaaaggcca ctgccacatt ctcagcagac ttccacttgc     2880

ctaatgagat tagtgattca actgacttga agcacagtaa catcttattt tatgcacatt     2940

ccctgtcttt tgctggactg atgaagccag tcacccgccc ttctctgttt tttggttttt     3000

tttttcttaa ccccaggtat atggaagggg agttgccttc acttttctgg aaatttgtct     3060

tcgtctgaca tattagaggg cctcgttttg tcctgttctt gttcagaccc tctcgttcta     3120

cgtcctgtgc tgaggggact gtccgtaagc tacaggacag cgagctggtc ctttctgcca     3180

cttcttcccc actcccatgc ccaggaaggc ctggttgctg atgctacttt ataaatgagt     3240

tgcttgcatt ttcacagaga atgaaggaag acgtaacatg gctccagaaa cttttcacat     3300

gatgattggg atcgacaaaa aaatgctacc ctctagacta gacacatttc atggagacaa     3360

gcaaaatggt gccagggctg ggctgactgt gggatgggat ttggtactgc agacagattt     3420

tgatttccac agttgagctg gaaacaaact gtgccttcaa aaaatgactt ttctaactta     3480

aggttggtta tatgttaagt gtgctactaa cttaaaaaat agtggctggg cgcggtggct     3540

catgcctgta atcccagtgc tttgggaggc caaggcgggg ggatcacgag gtcaggagat     3600

cgagaccatc ctggctaaca cggtgaaacc ccatctctac taaaaacaca caaaaaatta     3660

gctgggcgtg gtggtgggcg cctgtagtcc cagctactca ggaggctgag gcaggagaat     3720

ggcatgaacc tgggaggcag agcttgcagt gagccgagac agcgccattg cactccagcc     3780

tgggcaacag agcaagactc cgtctcaaaa aaaaaaaaaa aaaaaaaata gtgcactctc     3840

tggctggtca cggtggctca cgcctgtaat ctcagcactt tggaaggcca aggcaggcgg     3900

atcacgaggt cagaagatcg agaccatcct ggctaacaca gtgaaacccc gtctctacta     3960

aaaatataaa aaattagtcg ggcatggtgg cgggcgcctg tagtcccaac tactcgggag     4020

actgaggcag aagaatggcg tgaactcagg aggcggagct tgcagtgagc caaggcgaca     4080

gagcaagact ctgtctcaaa aaataaaaaa tagtgcactg tccttcgaga aagttttcta     4140

acatctagta atttgtaact tagaagtgga gttgccttgt ggatgtcttt tttgcattct     4200

gtaggaaatg aaacgtgaat ttaactcggg ttgcaagaaa taaaaatgtc agtgcattta     4260

aaaaaaaaaa aaaaaaa                                                    4277


<210>  441
<211>  2045
<212>  DNA
<213>  homo sapiens

<400>  441
tgcgtgccgc cgttgatccg gtgctgcagt gaggaggtgg ttcttgcccg tgttgtgtgt       60

gtgtgtgagt gagagagcga gtgagtgagt gagtgagtgt gtgtgtgggg gggactcggc      120

ttgttgttgt cggtgacttc cccctcccct tcaccccttc ccctccccgc cgccgctgca      180

gtggccgctc cctgggccgt aggaaatgag cgataacgat gacatcgagg tggagagcga      240

cgaagagcaa ccgaggtttc aatctgcggc tgacaaacgg gctcatcata atgcactgga      300

acgaaaacgt agggaccaca tcaaagacag ctttcacagt ttgcgggact cagtcccatc      360

actccaagga gagaaggcat cccgggccca aatcctagac aaagccacag aatatatcca      420

gtatatgcga aggaaaaacc acacacacca gcaagatatt gacgacctca agcggcagaa      480

tgctcttctg gagcagcaag tccgtgcact ggagaaggcg aggtcaagtg cccaactgca      540

gaccaactac ccctcctcag acaacagcct ctacaccaac gccaagggca gcaccatctc      600

tgccttcgat gggggctcgg actccagctc ggagtctgag cctgaagagc cccaaagcag      660

gaagaagctc cggatggagg ccagctaagc cactcggggc aggccagcaa taaaaactgt      720

ctgtctccat cgtctcatcc tcctttcagt tcgttggtag agccctcaga accatttaag      780

agactcttta tttttctctt tctccctttt ttttttaaat ttttattttt acgtagaagc      840

tcttggacaa cagctctcgt tctccttccc catttccact gtatattttt taatgtattc      900

ccttcaggga ttccctgtcc ccaacaggaa tttttaaacc aaaacacccc aacttggcag      960

ctttttctgt ggaggacaga cggccggccg gacctctgag cacatagtgt cctgcccacc     1020

ctaccagctc ctccagccct gccgggcaca tgcccggggg acgcctgccc tgcccaggtg     1080

gcctcctggc ccgccctcac ctctgataga ctttgtgaat ctgaactgct ctactttgag     1140

aagatgaccg gtttggagta atcagaatga accctcctcc tttttaaggg tttttttttt     1200

ttcctttttc taaaaagcta tgtatcgctc ctattgaaag accagatcct tagagaagtt     1260

tgtggtataa aaaggaagtg gggacagatt cgcagcacag agtcgctggc atgtttcact     1320

cctgcttctc tcagccagct gtttaagcct gcggcgccag cctcacggag ggccgtgtga     1380

cactctcgtg gtatgtatgg gagatggcag cagtgaagca gcagccacca gggagtggcc     1440

atttggggtt gggacaggga gggtgttttg ggtggcatag aggttttgta ttgagggcca     1500

gtgatgatgt tttgatattt atttcctgct acttaaattt gaatctgagt gaattgtacc     1560

tatttctgat gatgtcggtc ttgcaaagcg acagattcat aaagtaatga tgaaatcttt     1620

ctttcttccc gtgtgtattt ctaagaaata gagccaactg attttgtatg taaataccaa     1680

gagcaattta cctggtacta aacccgcacc ccagtgcgga cccttcccag ccctcatccc     1740

acttcctttc ctactgtcct ggaacctgtc tccattgtgt gatccagccc tggttctggc     1800

tgtggtcagc agatgccagt gaagggtttt gtgtgtttag gcctcatttc tttgtctttt     1860

tcctactccg ttcctggcat ttgctgattt ctagtgtata ctctgtagtc tcagttcgtg     1920

tttgattcca ttccatggaa ataaaaagta tgttgtacat actgccgaag aattgtcttg     1980

caagttaagg cttccccctt tactataaga ctataaataa aaacttattt tatccttctt     2040

aaaaa                                                                 2045


<210>  442
<211>  8413
<212>  DNA
<213>  homo sapiens

<400>  442
ccgccgccgc ccggcacccg aggagagggc ggcgggcgcc cctcggggaa gatgaaggcg       60

gaggggggcg accactccat gatcaacctg tcggtgcagc aggtcctgag cctctgggcc      120

cacgggacgg tgctgaggaa cctcacggag atgtggtact ggatcttcct ctgggctctc      180

ttctcttctc tgtttgtcca tggtgctgca ggagtgttga tgtttgtgat gctgcagagg      240

cataggcagg gaagagtcat ctctgtcatt gcagtcagca ttggatttct ggcttctgta      300

actggagcga tgattaccag tgcagcagta gcgggcattt acagagtagc tgggaagaac      360

atggcccctt tggaagcgct ggtatggggc gttggacaga ctgtactgac attaatcatc      420

tccttttcaa ggatcctcgc tacactttga ggtttctgtg ggaatgtctt acttcacata      480

aggaaacaga tgtacagatt ccctgaaaac ggcattgtta acaagtggaa atgaaattgt      540

gcaagaatgt ggactgagca ggtcaaagca taaggaagac cttgagctgt gtggaaggat      600

tgccctctgg tgttcaagtg attgcactac cgcactgcac cttatgtgcc tctgtctcag      660

gcaaggtgca ttaagacact atgtaaagtt acaagaaaaa gcaccttgtt tagctgccta      720

tcaggttaac attggtgttg aaatcatcgt tcctaacagt gttatgttaa gttacaggga      780

cgttttgagg tattgatata tgtgccaaac tcttttcttt ttgttaacat tgatcatgtg      840

acaatttgca agtgtagatg tagctgagtg ctgtgaacat atttgacatg aattcaggta      900

atgtactaag atttttgttc ggtaacacta aatcccgtat gagtgctaaa tactgaattg      960

tttaatatga gagaaattat ttggttttta atgttgcgcg tttctgggat ttagggcttc     1020

aatatgttta ggtattattg ttatttaatt gatgtggaag ataagtcttc ttaactgaag     1080

actagctcaa ctgttttaag aactcagagt agctctatag ggtgcatact tttcaccaac     1140

ttaagtaaca cccttttaat agcttctctc atgcatccat attctgttta tacaaattca     1200

gaaacttgaa gggtcataca cattgattgt agtttgtgcg tcataaaaat gtaatttgaa     1260

gattttctta aaaatttttg taagaaaaaa gtctgaaatg catgttgcat tctttgaccc     1320

ttctaaagaa agtttttgcc ttgtatctca tggacaaaac atctttataa ctagtatctc     1380

agtgggattg tattacgtgt tgcatatatc ttgatttttg acaaaacata aacagtcttt     1440

cattctggag tattaactgt ttttagagac tggcctaaat taggctctgg aaataaagac     1500

ctcatttgta gaaataagta acaagtaagt tatataggaa gagtaatgaa ctattttact     1560

ttggacatgt ggcaacatca taattttgct aagtaaaaat tggggaatat agtagataat     1620

tttaaaattt ggcaattagt ctcagcatat caatgcagta ctgagcgtgt attagagtaa     1680

ttcagttgtt cagttcttga tttatgatat gaagttatga tttaagttta gtagaagaat     1740

ctgtgagggc atatagcaaa agtggaaatg tcctttatat aaaacatttt aagaggttct     1800

ggcaatacgt aattgtaaga gtataggaag tagggttgaa ctggtctcct aatgagattt     1860

tttttggcac cagatacaat tataatgtgc taactcaaag gagacattgc agagaatatg     1920

aagttaagga taatccaaaa ataacctggt agccttgctg tttaatccaa tttgctataa     1980

aagtaggcct ttgttatatt acattcaaat ttaagaactt tgttacccat accacttttt     2040

ctctatccag aagcagagta tatccacaac ttaccaatga gaagttggag aggcagtact     2100

tttctcagta tggaagccaa tttgggagat ttactaacac tggcttggaa atttgtttta     2160

aaaaaataat aagcaactat gcatggatct ttgaagtaaa tcttaaaatt gattattttt     2220

attatgtaca ggcctgaaat tgttttcatg tgttctttat attcctgatg tttttacaaa     2280

ttaaatttag gcataacttt tccaagtcaa tctgattttt tcttttctgc cagacttgaa     2340

ttgtgttctt cttttacttt ggctattctg tcaataattt aaagcattcg tattcttcca     2400

gaggaattac caatagcatg tggaaattgt ttcagatctc cagaatgaat acttatttta     2460

acatatgttt attttatgat ttaagaaagt tatggtaaag taatatggag catgattcat     2520

aatccaaaat taacaagaaa ataacttgga tacattaaat gtactaatgt gtggaccaaa     2580

gagatttaaa ctattgtttt tactctagaa tgaaagtata attgaacggt taataattag     2640

tttgtagagt gtcctgcagt tattatcaag ttgctttaca ttatcaattg tgtgtgtatg     2700

tgtatacttt taattttagg ggttattttt ggtttctttg ctgttttcag ttatttccat     2760

tgagattttg tgcaactgtc tctcttttga tgttttgaga tgcagttgaa tagtttgagt     2820

ttgtgaattg tcttaatagc tatttatatg ctgaaatttt taaaaagtta gtagctttcc     2880

tatagacaca agaaatgttt aatgatatat atacacacac gtatatatca ttatataggt     2940

atatagagag ctgctatata tgaatacagt ctacttggaa agcttttttt cagtgaacac     3000

tttcatgttc tagtggaaaa tttgttcagt gtaatgatct tttaaatagg tttgaggatg     3060

tttgaaaatt ttgaattttg ggaaaatttt cttcacttaa tagagctgga gacccttgtt     3120

tgggacatga caaaagtcct tattgatgta tttgggttat atactttgtt aaaattcgta     3180

tgtgatttag cagtacattt tcttcgtgac aaatgcaaga agggagggag gatcctctat     3240

agtggacact cctttattta aaaaatgttt aataaaatat tgtttatagt gaaatcagct     3300

ccccaaagaa ggaactccta catgcccaaa ctaattacag ttgaacatac tgattaaaaa     3360

tgccatagat cacagctagt caggaggcct caaataaact gcaaataatg cttaaaactt     3420

taaaagaagg agaaccagca gtcttccgaa ccatgggaca gttccaaggt aatagcctac     3480

cttgcctagg ataagtgaag tcctaaatga tggctatctt cagggcctgg agcagaatta     3540

ttctttagat cttaatgttt accaaacagt gttacagttt gttacccaat atactttctt     3600

agtatttgca gcatacattt cactgctcaa aaaagtataa gggttttgtt tgtactttaa     3660

atgagagaaa taaagaaatg agttggcctg tatatcttgt atttgtgata tgagcaacgg     3720

gataatttga aatcacagaa tgttgtggga aaggtcttta aagaacctct aatgaagaaa     3780

atgtggctgc cacattgatg tacctaggct gccactcata cagcaaataa ttctattttg     3840

taaacacttc gtgtggatcc actatgtaaa gtgctctacc aagtattttc tctagtaaga     3900

agtacaagaa ttaccaagat ggaattcttt accttgagta caccaagagc tagcaagatg     3960

atttttaaat cctaaaaagt ttgggacaac attttgcttc ctgattttag ttgagagtta     4020

gcctgttatc cctccaaatt ctcattttcc tggttcatcc actaaataga atttccataa     4080

ctgagatatc atggctgtga catagtgaag agaatacgag actccaagcc agcaacacag     4140

attgaattaa gactctgtca cttgtcaact ttttgacctt gagcaaatca cttaacttct     4200

ctgagcctca gttcatactc cgtaaaatgt gactaatacc tcatgtagtt attgtgagga     4260

ttacgtgaga ttgtttatga atggcaaagc agtatgtatt tcacagtaaa tgatcaactg     4320

atagtctcta gaattttttt aaattacatt ttgcaattgc attaccaatt gaatatgttg     4380

ttttgtaaaa ttcatcaatt ttgtttcatt tctatatttt ccttacatat gctttaggaa     4440

agaaactaaa aacgttttct tataatcttg cttcatctcc ttttcacttt ttctttttaa     4500

aatcagcaga tctttaagaa ccttttgtga attggtggtg gtggaaatgg ccagtgcaag     4560

caggattaaa ttaggagttc tgttgaccac tggttaaaat aggaaaaggg tagagaggta     4620

gtcagccttg actcccttat ctattcccac ttacttccct tggattcatt cagccatgtt     4680

gatttattga ctttctgcta tttgctaatt attcttcttg aaaagtaaga gcgatatata     4740

acccttcagt cttctatatg tctgtttctt ctgccggccc tgggcccttg gctctacagt     4800

gtagtgccaa ttctgtagaa aaatagaacg atattcagtg tctaccaagt tctttcttcc     4860

acaggccaag ggtgcttaag ccctagctgt tattttgttt cttttattta tttatttttt     4920

gagacggagt ttcgctcttg ttgcccaggc tgcagtgcaa tggcatgatc tcagctcacc     4980

gcaacctctg cctcccaggt tcaagcgatt ctccttcctc agcctcccga gtagctggga     5040

ttacaggcgt gcaccaccat gcctggccag ttttgtattt ttagtagaga cagatttctc     5100

tatgttggtc aggctggtct caaactcccg acctcaaggg atccacccac cttggcctcc     5160

caaagtgctg ggattacagg tgtaagctgc cgtgcccagc ctattttttt ttaacttcaa     5220

atactattat tttaaattta tgttcattat gtaattcagg gagtaacgat gcctggagca     5280

atttctgaaa tattctcaaa ccacttcact cttgacacta cagatttttc tctcagtctc     5340

aatcagaatc tctgcagtca ttatttgttt ttaagatgtg agggacgagg aaaattactg     5400

aagaaattct agcagatttc gattgcagag aaatttggta acactttttg ggtaactggg     5460

taaattacta tttcttttaa taatcgggtg aaactctgaa ttgttaaaac ggaccaataa     5520

tcaaatggtt ttataatctt tcttaacttc ccgtccttgt tataacatct tggaagaaga     5580

ctcttcagga taaaaaggat attatttgat taaaaattat agcatttgga gaggtaacac     5640

acaaaaacaa aaacatattt gacaaagcgc cctacatcct gtgttttgtt aggactagaa     5700

actatactgg atgagtatgt atactgcatg tttacacatg ctgtgtttct ttatatgtga     5760

ggcttcactg accaccgtgc attttgaaat tgtattgcat tttgtgtgtg tgtgtggtga     5820

caggtttgct cttctcactt aaggagctct ggtctgtgta ggcagtacag tgttgttagg     5880

gaggttgctg aattatctaa aaatgtatcc atgaatttgg gggaaataat gcttaatatc     5940

tgaagtattt tcagtaaatg tggagatata tcagataata cttttaaatt agtggaaaca     6000

catttctgag tgaactgagc tatgaactat aatcatctct tcccctgagt ttagggaagt     6060

tgttttcaca ttctttacat ttattgcaca tatactgaac ttacataata actcttccct     6120

gattttgaga acgaatttag caatttccta aaaatcttcc tcctctttcc atacagatgt     6180

cgtatgttat agtttaaaca tatgtacaat ttgttgatag aatccaagga gctggtttag     6240

gaaagaatac tcttaacccc tacagttatg cagctctaat cttactgaaa agtaaatact     6300

ttaggcaagt caggagagca tgaacctcat acatacattt ttacgattat gtactgcacc     6360

cacatgtatc tactcttggt agtaacatga ctccaccctt tttgggaatg tatttaggtg     6420

gataactgaa acggaaaagc agtttgacac aaatacacag aaagaggaat tgcggtgcat     6480

aatcaatcgt ctgagtccca taactgtaac actttttctc ttataaattg gtagttccta     6540

aaaatcacca ctttaaaaat tttattctgt cttgctgaat taagcagaaa tcactttttt     6600

tagagccttg tttaaaggaa cgttaactcg agagtactac tgatgatgac gcttctcttg     6660

tttttaaagt atttacacat cattgttaag tatttttgga atggaacatt ttaaagtttt     6720

ctccatagaa agcaacatag tggcacttgt tgagtaaatg atcataaaaa tgacttgctt     6780

ttaatagcag atgagttgat agtttaactg ttgacacttt cttaatgttt ttgatgttgg     6840

atgcatttac aatggaagaa tttttttgaa agatttggcc ctctcaccaa tacacacatt     6900

cagacttgag ctgcacgcat ttagatgaac aaataggaaa ttcacggtat tttttgtttt     6960

agccatccaa aattcatagg attctaccaa aaatattagc ccctgactct agttattctg     7020

agatgaggga atcaacttta tcttgaaagt taactagcta aaatgtcttt atttaaatag     7080

caaaaatata gtttacctga caagtattaa aagtctcact ttcaaattgt gttaactctc     7140

agaccactga tgaatctttt ggtaaatcac aggcagattt taaaagctaa atgaagcctt     7200

agtgccttga aagttaagat acttgtgcaa aatggattta gcaagattca ggattggcac     7260

cagtgagttg gctagataca catcaccagt gactgggaat tcaaagttta gaaagcctaa     7320

cgaatagtag ctactaactt catatggttc aatgtaaatc agttacttag tcattgactg     7380

tgacagatga cagctacttt cactatattt tcatgatgtg gtatttttct ctattttttc     7440

tttttccaag tatgaaatgg aaaaaaatgt agttaagaaa attaagtgtg agactttaaa     7500

atttagtttt gttgtaaact agagattcta gtgaacagtg ttagttttat actgtagtac     7560

agggcacaca ctttaacctt tagaaatatg tttaccatca gggatttatt tttactatag     7620

aaatactaaa tgtactgtga agcttaaaga caggagaata aatgttggag gggtaataca     7680

caaaaacaaa ggcatatttg atgaagtacc ctgtgttatg tgaacacaat ttccccttct     7740

gttaagacta taaactatat gagtatgtgt actgcatgtt tacataaaac agtttaattt     7800

tgaaggatta ttttaaaaac tatgtttata tataatacct aacaagctgt aaatattgta     7860

tattattgat ttttaatttt atataagcaa ttttttattt cccaattcat gtacaaatct     7920

cattatgtat atagcataat ttcctggaga acacaaattt tgcagtgaat tttaagtaat     7980

tttaattgca gtaagcatca gtttagccta gagatgttga tctttatttt aaattatttt     8040

tcaccattct cattttcttc aaagggcagc aataaacata tgcaagttat ttttaattat     8100

agaaagtagg tctacaaaga taagatctag gttccaattc attgctttaa ggaaaagatg     8160

cacaattact atcattcagt gtctaatcac aggaccattt ctgaggtcca catgtggctc     8220

tcctctttgt aatatacagg gtgaactctt tactgataca cacaagacaa ctgttaaaaa     8280

gtgaatccag cacttaaatg tcattacaca gaatttattg gattaaaaat ttgtaatata     8340

cagtatttta ataaagtttc tgtattcaat ttcatgcact tatatataaa taaacctgtc     8400

tttgaaagct tta                                                        8413


<210>  443
<211>  2416
<212>  DNA
<213>  homo sapiens

<400>  443
gactgcagag ccggggctgg gctaggcgcg cgcttggaga gcattgcgcg cggctgggcc       60

cgcggccggc ggctcctcct cccactctgc tcctcctctt ttttctcctc ctccacctcc      120

tcctccgcct cctcctcctc ctcttcctcc tcctcttcaa ttctcccggt ggctcgactc      180

ggctcgcagg cttcggagaa acccctactc cagtcgccga ctcagcgccc aagagggtcg      240

ccttgggctg ggggcgcacc ccagggaggg gaggggtcca ggcagctggg ccgccgcgga      300

cacctagcgg cttcagggtg aaccccgacc gcagccgtcg ccgcctcggg cagagtttgc      360

gcccttgctt tgcgccccgg gcgctgaagc cgggcgggcg atgcccgcgg cgtgaaagcg      420

cccgcggcgg gcgccgacct ctgtcctagt ctcctgctcc ccccgccccg cttgtcccgt      480

gcccttgtga ccctggcttt ggcgccgtcg cccaggcgcc ccgcaatgta gctgcccctg      540

cgcctcggcg ggaggcgtcc tgccccgcga gcgcccgggg cccggagccc ggcctggggg      600

ctcagccgag ctcgggcggg gccggggccg cggtggcgat gcaccgggcc cgttagcgcc      660

aggagcgcca ggcagctgag gcggggggca agccctccct cggaggagcc gcgcccccgg      720

ccccgccggt cccgccgcga tgctgttcca cagtctgtcg ggccccgagg tgcacggggt      780

catcgacgag atggaccgca gggccaagag cgaggctccc gccatcagct ccgccatcga      840

ccgcggcgac accgagacga ccatgccgtc catcagcagt gaccgcgccg cgctgtgcgc      900

cggctgcggg ggcaagatct cggaccgcta ctacctgctg gcggtggaca agcagtggca      960

catgcgctgc ctcaagtgct gcgagtgcaa gctcaacctg gagtcggagc tcacctgttt     1020

cagcaaggac ggtagcatct actgcaagga agactactac aggcgcttct ctgtgcagcg     1080

ctgcgcccgc tgccacctgg gcatctcggc ctcggagatg gtgatgcgcg ctcgggactt     1140

ggtttatcac ctcaactgct tcacgtgcac cacgtgtaac aagatgctga ccacgggcga     1200

ccacttcggc atgaaggaca gcctggtcta ctgccgcttg cacttcgagg cgctgctgca     1260

gggcgagtac cccgcacact tcaaccatgc cgacgtggca gcggcggccg ctgcagccgc     1320

ggcggccaag agcgcggggc tgggcgcagc aggggccaac cctctgggtc ttccctacta     1380

caatggcgtg ggcactgtgc agaaggggcg gccgaggaaa cgtaagagcc cgggccccgg     1440

tgcggatctg gcggcctaca acgctgcgct aagctgcaac gaaaacgacg cagagcacct     1500

ggaccgtgac cagccatacc cgagcagcca gaagaccaag cgcatgcgca cgtccttcaa     1560

gcaccaccag cttcggacca tgaagtctta ctttgccatt aaccacaacc ccgacgccaa     1620

ggacttgaag cagctcgcgc aaaagacggg cctcaccaag cgggtcctcc aggtctggtt     1680

ccagaacgcc cgagccaagt tcaggcgcaa cctcttacgg caggaaaaca cgggcgtgga     1740

caagtcgaca gacgcggcgc tgcagacagg gacgccatcg ggcccggcct cggagctctc     1800

caacgcctcg ctcagcccct ccagcacgcc caccaccctg acagacttga ctagccccac     1860

cctgccaact gtgacgtccg tcttaacttc tgtgcctggc aacctggagg gccatgagcc     1920

tcacagcccc tcacaaacga ctcttaccaa ccttttctaa tgactcgcaa cccctcaccc     1980

cacaatttct ttaaaaaaga aattatcttt agttgaattc caagtgtatt ttaaaataga     2040

ggctttgagc aactaactaa ccacatttta ggatctcgcc tggaaacaga ggtaaaaaaa     2100

agaagtgtgc gcccggctaa tgcagcggtg tggaccgagg aacaacttgg aagatctacc     2160

tgcaacacaa catttgtgtc actgtacagt tttgtggact gagcgaggaa aaacaacaaa     2220

taatttaagt tggctagagc ttctgtattt tcaaagactg ccacgtgcct taggaatact     2280

gttttatctc catactttgg atgacttgtt catttttctc tccctctttt tctctgtata     2340

tttatgacca gagcaaaaat gtaaaaaaca aaaaaaacaa caaaaaaagt ttgttacttt     2400

gaatagtcct aaaaag                                                     2416


<210>  444
<211>  2900
<212>  DNA
<213>  homo sapiens

<400>  444
gcagtaccca agcgagccat ttaacatggc ggaggatgtt tcctcagcgg ccccgagccc       60

gcggggctgt gcggatggta gggatgccga ccctactgag gagcagatgg cagaaacaga      120

gagaaacgac gaggagcagt tcgaatgcca ggaactgctc gagtgccagg tgcaggtggg      180

ggcccccgag gaggaggagg aggaggagga ggacgcgggc ctggtggccg aggccgaggc      240

cgtggctgcc ggctggatgc tcgatttcct ctgcctctct ctttgccgag ctttccgcga      300

cggccgctcc gaggacttcc gcaggacccg caacagcgca gaggctatta ttcatggact      360

atccagtcta acagcttgcc agttgagaac gatatacata tgtcagtttt tgacaagaat      420

tgcagcagga aaaacccttg atgcacagtt tgaaaatgat gaacgaatta cacccttgga      480

atcagccctg atgatttggg gttcaattga aaaggaacat gacaaacttc atgaagaaat      540

acagaattta attaaaattc aggctatagc tgtttgtatg gaaaatggca actttaaaga      600

agcagaagaa gtctttgaaa gaatatttgg tgatccaaat tctcatatgc ctttcaaaag      660

caaattgctt atgataatct ctcagaaaga tacatttcat tccttttttc aacacttcag      720

ctacaaccac atgatggaga aaattaagag ttatgtgaat tatgtgctaa gtgaaaaatc      780

atcaaccttt ctaatgaagg cagcggcaaa agtagtagaa agcaaaagga caagaacaat      840

aacttctcaa gataaaccta gtggtaatga tgttgaaatg gaaactgaag ctaatttgga      900

tacaagaaaa aggtctcaca agaatctttt cttatctaag ttgcaacatg gaacccagca      960

acaagacctt aataagaaag aaagaagagt aggaactcct caaagtacaa aaaagaaaaa     1020

agaaagcaga agagccactg aaagcagaat acctgtttca aagagtcagc cggtaactcc     1080

tgaaaaacat cgagctagaa aaagacaggc atggctttgg gaagaagaca agaatttgag     1140

atctggcgtg aggaaatatg gagagggaaa ctggtctaaa atactgttgc attataaatt     1200

caacaaccgg acaagtgtca tgttaaaaga cagatggagg accatgaaga aactaaaact     1260

gatttcctca gacagcgaag actgattgtg tttgtaaaag cttgatgaaa ggacagttaa     1320

gtattttgat cactgcattt tgtttgaaac ttgtgtcatt gatgtaattt aaaacttttg     1380

tttaaagcat tacagtattt ttctgtgacc atcaattaat gagggtttgt gctaccagag     1440

ttaaagcata tgctatcatt gtattcttta agaaccttat tttgataaaa tgtaaatttg     1500

ttgaaccctg ccacatttag tatccccacc cccaaatcct gttccaatga aaaaattaaa     1560

acctgatacg aaaaaaaaaa aattccagtt aacctatttt gtgtctgtag gctgacctca     1620

accctgtaac gtaacccatt aaaatgaatt tctttttttt taagacagag tttctctctg     1680

ttgcccaggc tggagtgcag tggcgcaatt tcagctcact gcaacctctg cctcccaggt     1740

tcaagtgatt ctcctgcctc agcctcctga gtagctggga ttacaggcac acaccaccac     1800

gcccagctaa tttttgtatt tttagtagag gcggggtttc accatgctgg tcaggatgtt     1860

ctccaactcc tgacttcatg atccacccac ctcggcctcc caaagtgctg agattacaga     1920

cgtgagccac tgcgtcctgc ctaaaatgaa ttttctagat gattgaataa cagtagtcct     1980

ttgatagaag ataatgactt ggtttatggc cttaatatac tacttaatta cttaagatgt     2040

ttattaatag aatgataaat gtacagagta acctataagc atgacatact tttgctttca     2100

gtagtttcat gtaaagaaaa aaacttgaaa atagtaatac ctgagtaccc atgggaataa     2160

tagacactgg ggaggtaggg tggggagcgg gagcaagagc tgaaaaactt acctactggg     2220

gactgtgctc actacctggg tgacaggatc atacgtaccc caaacctcaa catcacacag     2280

tatactcagc taacaaacct gcccatgtgt ttcctgaatc taaaataaaa atcgaaataa     2340

tttttttaaa aaagaaaaag acaatagtat tacccatggg acaaaatttg tactattagc     2400

aagaatcatt ttgtgtctca tttagaaaca atttgacttt tgttccagtg tttaaacttt     2460

gacaaaaatg gttttgaata gatctttata acctgatgcc ataaatacaa gattctctga     2520

taccttcatt taatatatca atattgggcc taaaacagta ttctgtaaag cttaaattgg     2580

tattaactat gatcatcttg atgtctatga tagataataa acaaggtcat acatacctta     2640

ctaaacaatt ttggtttttc accaacattt tattctttaa aagatttaga ctaacagaat     2700

tatttagcat ttcgagtcat gtgctttatt tagcaagtga gtaaaaatat tggaatattg     2760

aagtatttgc ataaaaaatc aaatggtggt gttttgtaat ctctattgta tttcctatta     2820

aggtttcata tattactttc ccattgttcc tgaatttgtt atcctatata taaacagaaa     2880

catggatgag taccatatac                                                 2900


<210>  445
<211>  6406
<212>  DNA
<213>  homo sapiens

<400>  445
ggggctggac ccggcgcgga gctggctgag tcggagcgca gcgtcctttg tgcccggcgg       60

ccgccccggg atgcgtccga gctaggagcc agatccagga tgggggcccc gtttgtctgg      120

gccttgggcc ttttgatgct gcagatgctg ctctttgtgg ctggggaaca gggcacacag      180

gatatcaccg atgccagcga aagggggctc cacatgcaga agctggggtc tgggtcagtg      240

caggctgcgc tggcggagct ggtggccctg ccctgtctct ttaccctgca gccacggcca      300

agcgcagccc gagatgcccc tcggataaag tggaccaagg tgcggactgc gtcgggccag      360

cgacaggact tgcccatcct ggtggccaag gacaatgtcg tgagggtggc caaaagctgg      420

cagggacgag tgtcactgcc ttcctacccc cggcgccgag ccaacgccac gctacttctg      480

gggccactga gggccagtga ctctgggctg taccgctgcc aggtggtgag gggcatcgag      540

gatgagcagg acctggtgcc cttggaggtg acaggtgttg tgttccacta ccgatcagcc      600

cgggaccgct atgcactgac cttcgctgag gcccaggagg cctgccgtct cagctcagcc      660

atcattgcag cccctcggca tctacaggct gcctttgagg atggctttga caactgtgat      720

gctggctggc tctctgaccg cactgttcgg tatcctatca cccagtcccg tcctggttgc      780

tatggcgacc gtagcagcct tccaggggtt cggagctatg ggaggcgcaa cccacaggaa      840

ctctacgatg tgtattgctt tgcccgggag ctggggggcg aggtcttcta cgtgggcccg      900

gcccgccgcc tgacactggc cggcgcgcgt gcacagtgcc gccgccaggg tgccgcgctg      960

gcctcggtgg gacagctgca cctggcctgg catgagggcc tggaccagtg cgacccgggc     1020

tggctggccg acggcagcgt gcgctacccg atccagacgc cgcgccggcg ctgcgggggc     1080

ccagccccgg gcgtgcgcac cgtctaccgc ttcgctaacc ggaccggctt cccctcaccc     1140

gccgagcgct tcgacgccta ctgcttccga gctcatcacc ccacgtcaca acatggagac     1200

ctagagaccc catcctctgg ggatgagggg gagattctgt cagcagaggg gcccccagtt     1260

agagaactgg agcccaccct ggaggaggaa gaggtggtca cccctgactt ccaggagcct     1320

ctggtgtcca gtggggaaga agaaaccctg attttggagg agaagcagga gtctcaacag     1380

accctcagcc ctacccctgg ggaccccatg ctggcctcat ggcccactgg ggaagtgtgg     1440

ctaagcacgg tggcccccag ccctagcgac atgggggcag gcactgcagc aagttcacac     1500

acggaggtgg ccccaactga ccctatgcct aggagaaggg ggcgcttcaa agggttgaat     1560

gggcgctact tccagcagca ggaaccggag ccggggctgc aaggggggat ggaggccagc     1620

gcccagcccc ccacctcaga ggctgcagtg aaccaaatgg agcctccgtt ggccatggca     1680

gtcacagaga tgttgggcag tggccagagc cggagcccct gggctgatct gaccaatgag     1740

gtggatatgc ctggagctgg ttctgctggt ggcaagagct ccccagagcc ctggctgtgg     1800

ccccctacca tggtcccacc cagcatctca ggccacagca gggcccctgt cctggagcta     1860

gagaaagccg agggccccag tgccaggcca gccaccccag acctgttttg gtcccccttg     1920

gaggccactg tctcagctcc cagccctgcc ccctgggagg cattccctgt ggccacctcc     1980

ccagatctcc ctatgatggc catgctgcgt ggtcccaaag agtggatgct accacacccc     2040

acccccatct ccaccgaggc caatagagtt gaggcacatg gtgaggccac cgccacggct     2100

ccaccctccc ctgctgcaga gaccaaggtg tattccctgc ctctctcttt gaccccaaca     2160

ggacagggtg gagaggccat gcccacaaca cctgagtccc ccagggcaga cttcagagaa     2220

actggggaga ccagccctgc tcaggtcaac aaagctgagc actccagctc cagcccatgg     2280

ccttctgtaa acaggaatgt ggctgtaggt tttgtcccca ctgagactgc cactgagcca     2340

acgggcctca ggggtatccc ggggtctgag tctggggtct tcgacacagc agaaagcccc     2400

acttctggct tgcaggccac tgtagatgag gtgcaggacc cctggccctc agtgtacagc     2460

aaagggctgg atgcaagttc cccatctgcc cccctgggga gccctggagt cttcttggta     2520

cccaaagtca ccccaaattt ggagccttgg gttgctacag atgaaggacc cactgtgaat     2580

cccatggatt ccacagtcac gccggccccc agtgatgcta gtggaatttg ggaacctgga     2640

tcccaggtgt ttgaagaagc cgaaagcacc accttgagcc ctcaggtggc cctggataca     2700

agcattgtga cgcccctcac gaccctggag cagggggaca aggttggagt tccagccatg     2760

tctacactgg gctcctcaag ctcccaaccc cacccagagc cagaggatca ggtggagacc     2820

cagggaacat caggagcttc agtgcctccg catcagagca gtcccctagg gaaaccggct     2880

gttcctcctg ggacaccgac tgcagccagt gtgggcgagt ctgcctcagt ttcctcaggg     2940

gagcctacgg taccgtggga cccctccagc accctgctgc ctgtcaccct gggcatagag     3000

gacttcgaac tggaggtcct ggcagggagc ccgggtgtag agagcttctg ggaggaggtg     3060

gcaagtggag aggagccagc cctgccaggg acccctatga atgcaggtgc ggaggaggtg     3120

cactcagatc cctgtgagaa caacccttgt cttcatggag ggacatgtaa tgccaatggc     3180

accatgtatg gctgtagctg tgatcagggc ttcgccgggg agaactgtga gattgacatt     3240

gatgactgcc tctgcagccc ctgtgagaat ggaggcacct gtattgatga ggtcaatggc     3300

tttgtctgcc tttgcctccc cagctatggg ggcagctttt gtgagaaaga caccgagggc     3360

tgtgaccgcg gctggcataa gttccagggc cactgttacc gctattttgc ccaccggagg     3420

gcatgggaag atgccgagaa ggactgccgc cgccgctccg gccacctgac cagcgtccac     3480

tcaccggagg aacacagctt cattaatagc tttgggcatg aaaacacgtg gatcggcctg     3540

aacgacagga tcgtggagag agatttccag tggacggaca acaccgggct gcaatttgag     3600

aactggcgag agaaccagcc ggacaatttc ttcgcgggtg gcgaggactg tgtggtgatg     3660

gtggcgcatg aaagcgggcg ctggaacgat gtcccctgca actacaacct accctatgtc     3720

tgcaagaagg gcacagtgct ctgtggtccc cctccggcag tggagaatgc ctcactcatc     3780

ggtgcccgca aggccaagta caatgtccat gccactgtaa ggtaccagtg caatgaagga     3840

tttgcccagc accatgtggc caccattcga tgccggagca atggcaagtg ggacaggccc     3900

caaattgtct gcaccaaacc cagacgttca catcggatgc ggcgacacca ccaccaccac     3960

caacaccacc accagcatca ccaccacaaa tcccgcaagg agcgcagaaa acacaagaaa     4020

cacccaacgg aggactggga gaaggacgaa gggaatttct gctgaagaac cagaaaaaag     4080

aaagcacaac acctttccca tgcctcctct ggagccttcg cctggggaga cagaacccag     4140

agagaaacaa gagagtccag aagtccctga accccaaacc acatccccca cacacataat     4200

cctttgtaca aagctcctct tttccctttt tttacataca caagatcctc ttggcaggtg     4260

gagccaggtg tctgaaaagt tcattctcgt ctggctgaac tctgggagtg tgtcccagct     4320

gagggaagca caagtagcaa agctcattgg tctggtctct tgtttgccag gctgattgaa     4380

gcaggccttg atgagggtgc atgagtgtat gtttgcattc acatgaagga attgcttttc     4440

acaccagaaa ttcagactta gtcaatgttg gctgaattcc taaatccagg aagaagcctg     4500

gacgtagggt cattagcttt gggaatagaa ggctacacag aagcacactg tttttgaact     4560

tgacaacagc tctcccttta ccctggactt cagcccaagt tccgtctttg gtcttggtgg     4620

ataaacacac agtgtggaga tcccacgtac tgcattttag ggatgttttt aggacaacct     4680

ccctccatgc cttcagagtt aggagtgaga atgatcaaag caatatgtag gtgatggagg     4740

gagagtgtat tgctaaccct tccaggtcta gtccagcgct gagatttggt ggttctgcat     4800

gtgtgatgaa tctctttcac acaaatagac gagaggatat ttagggctag atgagcccag     4860

atttcttccc cctccatctc tcagggagac aaagaacctc cttcctggac caaggaggtg     4920

ctgccaagtt ttctagccca gtgcacatac ccagtcctta agcagacatt ggtagtgccc     4980

ctgccctggg tcccactcct gccccacccc acccttgtcc ctggccattg cctggtggtc     5040

tagaaacact taaaacttga agtagtgaca cctacctgcg gtcatattgt agagagatgc     5100

tcagtgttaa aactgaaaca cacaaacaca cacacacaca catttttctc ttgtagattt     5160

taatttttta agtgggaaag aactcacctt gccttcctcc cccaaatgtg caacctgtaa     5220

aaggtctctc cacaccaggg gccaggatcc agttccctca tctctggcag gaaagatcca     5280

cagcttttcc tccatgtctg ttactcactt tcagcagtcc gggtaaaatc tgtggatcag     5340

ggttaaaaaa gcaccgtgga gaatggccct cttcaggaaa gaaaaataag caaatgaatg     5400

gtccacctag gggttcagta aagaaagaaa tgtgttaact gagcctgaat cccttctggg     5460

aagtaataat gaccattgac aactaagaag tagacaccat gctaaagact tacatacaat     5520

ctccttgaat cttctcaata gcccattgac ttagaaactg ttactttccc attttacaca     5580

cagtgaaact gaggctcaga tataaaggaa aggtactggc ttgaagtcac aaccacgaca     5640

ggagtaagga tttggaataa ggatttggtc ctgttttctg gaccaaatcc ttactctggc     5700

tctgcttaca ctttctctcc atcaccaaat ccttactcca aatccagaag tcagagccaa     5760

ctcccatctt ggttctgacc caaatcctgc tctggactct ggagaggaga ttgaaatata     5820

attgcaccct catacacatt taggaaatgg ttaagaagtg taaactgaac ccttatcctt     5880

gtcttcaatc ttcctccctg tagacatcta tcttattatg gttattattc agaaaaccca     5940

gggatacagg tttgtcttct tactttgata actcttctta gtttaaaata ataataataa     6000

cacatctttg gtcatctatg tcacacaaaa attttccttt gtttgcgggg ggctggggat     6060

gcagtgtttt ttggggggtc ttggtttatg ctccctgccc ttgagcccct cagccgtttg     6120

ccctgccccc acctcggctc catggtggga gggggctctg gtcttttcta aagtgggcgg     6180

tttgtctttt gatctttccc ttttggatgt gcgtgtgtgt ctgcgtgtgc catgtgcgtg     6240

gcacgcatat gagtgtgtgt gcgtgtgaac ggctttgggt cctgctggtt ttgctgtgag     6300

ctgcagtgtt ctgtgggtct gtggtatctg acactgtgga cattaatgta cttcttggac     6360

attttaataa attttttaac agttcaacct gcccgtcacc acctga                    6406


<210>  446
<211>  1875
<212>  DNA
<213>  homo sapiens

<400>  446
ctgcctcccc cccgctcccg ctcccctgag cccagccaga ccccgcgccg cccgcgcccc       60

gctcgactcc ggaggctccc gcagccccgg cgtccgcccc gctgccccct cccccggggg      120

ccatgggggc gcccccgggc taccggccct cagcttgggt gcatctcctc caccagctgc      180

cccgcgccga cttccagctc cgcccggtgc ccagcgtttt cgcgccccaa gagcaggaat      240

accagcaggc cttgttgctg gtggcggcct tggcgggcct gggcttgggc ctgagcctca      300

ttttcatcgc tgtctacctc atccgcttct gctgctgccg gccccccgag ccccccgggt      360

ccaagatccc ctcgcccggg ggaggctgcg tcacctggag ctgcattgtc gcccttctcg      420

ccggctgcac tggcattggc atcggtttct atggcaacag tgagaccagt gatggggtgt      480

cccagctcag ctctgcgctg ctgcacgcca accacacact cagcaccatt gaccacctgg      540

tgttggagac ggtggagagg ctgggcgagg cggtgaggac agagctgacc accctggagg      600

aggtgctcga gccgcgcacg gagctggtgg ctgccgcccg aggggctcga cggcaggcgg      660

aggctgcggc ccagcagctg caggggctgg ccttctggca gggagtgccc ctgagccccc      720

tgcaggtggc tgaaaatgtg tcctttgtgg aggagtacag gtggctggcc tacgtcctcc      780

tgctgctcct ggagctgctg gtctgcctct tcaccctcct gggcctggcg aagcagagca      840

agtggctggt gatcgtgatg acagtcatga gtctcctggt tctcgtcctg agctggggct      900

ccatgggcct ggaggcagcc acggccgtgg gcctcagtga cttctgctcc aatccagacc      960

cttatgttct gaacctgacc caggaggaga cagggctcag ctcagacatc ctgagctatt     1020

atctcctctg caaccgggcc gtctccaacc ccttccaaca gaggctgact ctgtcccagc     1080

gagctctggc caacatccac tcccagctgc tgggcctgga gcgagaagct gtgcctcagt     1140

tcccttcagc gcagaagcct ctgctgtcct tggaggagac tctgaatgtg acagaaggaa     1200

atttccacca gttggtggca ctgctacact gccgcagcct gcacaaggac tatggtgcag     1260

ccctgcgggg cctgtgcgaa gacgccctgg aaggcctgct cttcctgcta ctcttctccc     1320

tgctgtctgc aggagcgctg gccactgccc tctgcagcct gccccgagcc tgggccctct     1380

tcccacccag gaatccaagc gctttgtgca gtggcagtcg tctatctgag cccctcctcc     1440

cggctggact ggagcctggc tcccctcttc gttccttccc tggctgccgg aggagacccc     1500

actaacccag cctgcctggg ctctgaccac taacactctt ggccatggac agcctgcaca     1560

ggaccgcctc cctgctcttg gccactgtgc tcccatttct gtccttggcc ttgggagtag     1620

ctgagggggc agactaggga gtagggctgg caggggaggg ggcagacagc ctcgcctcgc     1680

acccttcatc cctggctgcc ggtcccatcc ttggagggac taagctgggg gtgggggaca     1740

tgagtccccc tgctgcccct gccacatccc agtgggctct gaccccctga tctcaactcg     1800

tggcactaac ttggaaaagg gttgatttaa aataaaaggg aagactattt tacaagcaaa     1860

aaaaaaaaaa aaaaa                                                      1875


<210>  447
<211>  5837
<212>  DNA
<213>  homo sapiens

<400>  447
cccgctctgc ttcagcgcac gctgaagacg gcactaggac ccagggaagt ccccgagcgg       60

ggttcgcgga aaggcagcca gactcctcct tatctccagt gtcaaacttg acatcagcct      120

gcgagcggag catggtaact tctccagcaa tcagagcgct ccccctcaca tcagtggcat      180

gcttcatgga gatatgctcc tctcactgcc ctctgcacca gcaacatgga ttgtcagctc      240

tccatcctcc tccttctcag ctgctctgtt ctcgacagct tcggggaact gattccgcag      300

ccttccaatg aagtcaatct actggattca aaaacaattc aaggggagct gggctggatc      360

tcttatccat cacatgggtg ggaagagatc agtggtgtgg atgaacatta cacacccatc      420

aggacttacc aggtgtgcaa tgtcatggac cacagtcaaa acaattggct gagaacaaac      480

tgggtcccca ggaactcagc tcagaagatt tatgtggagc tcaagttcac tctacgagac      540

tgcaatagca ttccattggt tttaggaact tgcaaggaga cattcaacct gtactacatg      600

gagtctgatg atgatcatgg ggtgaaattt cgagagcatc agtttacaaa gattgacacc      660

attgcagctg atgaaagttt cactcaaatg gatcttgggg accgtattct gaagctcaac      720

actgagatta gagaagtagg tcctgtcaac aagaagggat tttatttggc atttcaagat      780

gttggtgctt gtgttgcctt ggtgtctgtg agagtatact tcaaaaagtg cccatttaca      840

gtgaagaatc tggctatgtt tccagacacg gtacccatgg actcccagtc cctggtggag      900

gttagagggt cttgtgtcaa caattctaag gaggaagatc ctccaaggat gtactgcagt      960

acagaaggcg aatggcttgt acccattggc aagtgttcct gcaatgctgg ctatgaagaa     1020

agaggtttta tgtgccaagc ttgtcgacca ggtttctaca aggcattgga tggtaatatg     1080

aagtgtgcta agtgcccgcc tcacagttct actcaggaag atggttcaat gaactgcagg     1140

tgtgagaata attacttccg ggcagacaaa gaccctccat ccatggcttg tacccgacct     1200

ccatcttcac caagaaatgt tatctctaat ataaacgaga cctcagttat cctggactgg     1260

agttggcccc tggacacagg aggccggaaa gatgttacct tcaacatcat atgtaaaaaa     1320

tgtgggtgga atataaaaca gtgtgagcca tgcagcccaa atgtccgctt cctccctcga     1380

cagtttggac tcaccaacac cacggtgaca gtgacagacc ttctggcaca tactaactac     1440

acctttgaga ttgatgccgt taatggggtg tcagagctga gctccccacc aagacagttt     1500

gctgcggtca gcatcacaac taatcaggct gctccatcac ctgtcctgac gattaagaaa     1560

gatcggacct ccagaaatag catctctttg tcctggcaag aacctgaaca tcctaatggg     1620

atcatattgg actacgaggt caaatactat gaaaagcagg aacaagaaac aagttatacc     1680

attctgaggg caagaggcac aaatgttacc atcagtagcc tcaagcctga cactatatac     1740

gtattccaaa tccgagcccg aacagccgct ggatatggga cgaacagccg caagtttgag     1800

tttgaaacta gtccagactc tttctccatc tctggtgaaa gtagccaagt ggtcatgatc     1860

gccatttcag cggcagtagc aattattctc ctcactgttg tcatctatgt tttgattggg     1920

aggttctgtg gctataagtc aaaacatggg gcagatgaaa aaagacttca ttttggcaat     1980

gggcatttaa aacttccagg tctcaggact tatgttgacc cacatacata tgaagaccct     2040

acccaagctg ttcatgagtt tgccaaggaa ttggatgcca ccaacatatc cattgataaa     2100

gttgttggag caggtgaatt tggagaggtg tgcagtggtc gcttaaaact tccttcaaaa     2160

aaagagattt cagtggccat taagaccctg aaagttggct acacagaaaa gcagaggaga     2220

gacttcctgg gagaagcaag cattatggga cagtttgacc accccaatat cattcgactg     2280

gaaggagttg ttaccaaaag taagccagtt atgattgtca cagaatacat ggagaatggt     2340

tccttggata gtttcctacg taaacacgat gcccagttta ctgtcattca gctagtgggg     2400

atgcttcgag ggatagcatc tggcatgaag tacctgtcag acatgggcta tgttcaccga     2460

gacctcgctg ctcggaacat cttgatcaac agtaacttgg tgtgtaaggt ttctgatttc     2520

ggactttcgc gtgtcctgga ggatgaccca gaagctgctt atacaacaag aggagggaag     2580

atcccaatca ggtggacatc accagaagct atagcctacc gcaagttcac gtcagccagc     2640

gatgtatgga gttatgggat tgttctctgg gaggtgatgt cttatggaga gagaccatac     2700

tgggagatgt ccaatcagga tgtaattaaa gctgtagatg agggctatcg actgccaccc     2760

cccatggact gcccagctgc cttgtatcag ctgatgctgg actgctggca gaaagacagg     2820

aacaacagac ccaagtttga gcagattgtt agtattctgg acaagcttat ccggaatccc     2880

ggcagcctga agatcatcac cagtgcagcc gcaaggccat caaaccttct tctggaccaa     2940

agcaatgtgg atatcactac cttccgcaca acaggtgact ggcttaatgg tgtctggaca     3000

gcacactgca aggaaatctt cacgggtgtg gagtacagtt cttgtgacac aatagccaag     3060

atttccacag atgacatgaa aaaggttggt gtcaccgtgg ttgggccaca gaagaagatc     3120

atcagtagca ttaaagctct agaaacgcaa tcaaagaatg gcccagttcc cgtgtaaagc     3180

acgggacgga agtgcttctg gacggaagtg gtggctgtgg aaggcgtagc atcatcctgc     3240

agacagacaa taattctgga gatactggtg gaagttccaa gtccaataag acactcaaat     3300

atgagtacaa atgccttaaa atggaattga aaaactcttt attttcccct atcatttatt     3360

ggatgggtgg gtggggtatt tttttgtaat tgctttttta aatattagtt aatggattaa     3420

atttaattct tcagcgtaaa atggtgaaga actagcatat agccattgat cataaactga     3480

ctatcataaa atcaaaacaa gtgaaataac aaaatggaca tggtggcttt gtttaggtag     3540

agccacaaaa gaaaagactt gtaatatttt tatatacaga ggaaatctgt aacaggtatt     3600

ttgtttcttt taaagcaagc aacacagagg aatttatacc tcaaactatc tggccatatt     3660

tactacctta tcactgcatt attctctttt atctgtttaa agcatataga gatgaagttt     3720

gtagttgttt taagtactac acatttttaa attgttagct tccttaagta tatcatgtaa     3780

agaaatgtct taatttttga aaaaagtaca tatttatttt cttttgaatt gtttttattg     3840

ttttctattt atgccttgat gatttaatat ggatttgtta cagccaagtg ccaaatgctc     3900

tctcaaattg tcagcaattt aactagacac agataataat gggtttcttt cagatttttt     3960

gaaccatcca cttacatata tttttaaaaa atgaaatcct tttcctgttc atacactaac     4020

caaatctctc aaatctgtta tcccaatcat tgttgcctct ccgtttatta taaactgtat     4080

gctcacaact tagtgtaata taccagcttg tatgcaatgg attttcaacc agataacata     4140

cctttcctgc tctggtgctt agagactatc aactccctcc tttagtgaag gagccgtgtt     4200

agagcttccg agaatagctc cactggagag aagtggaatc ctatatagaa tgctgcacta     4260

attgacaaca cagcctatag gccaatgcat gagtaaaaaa aaaaacaatt actggctcac     4320

tggctttgaa aagtcactta ctattgttgc tgaaacttgc tgagctgttt atagagaatg     4380

atgataacag aacttttcct ctgtatcact ggtgtttagg tgaattaatt aaacattgtg     4440

atcattagta ccaggtatta ttatctttaa gagtcttcca cttcaatgca catggtgcag     4500

ttttggtgtg taacttagaa ggattgaact tctttgaatt tactggacat aacattttca     4560

gaatagttgg tcatctagca accgcctcaa aatgtgtaag caggagagaa atttctcatc     4620

acagggattt agacttacta ttacataaag gctaactatg agcttgctca ttaattttga     4680

aaagatgtac ctggtggata tctagctagt aatatattct gaagcaacat tttagctcta     4740

ttgatactct ttctaatgct gatatgatct tgagtataag aaatgcatat gtcactagaa     4800

tggataaaat aatgctgcaa acttaatgtt cttatgcaaa atggaacgct aatgaaacac     4860

agcttacaat cgcaaatcaa aactcacaag tgctcatctg ttgtagattt agtgtaataa     4920

gacttagatt gtgctccttc ggatatgatt gtttctcaaa tcttggcaat attccttagt     4980

caaatcaggc tactagaatt ctgtattgga tatataagag catgaaattt ttaaaaatac     5040

acttgtgatt ataaaattaa tcacaaattt cacttatacc tgctatcagc agctagaaaa     5100

catttttttt ttaaatcaag tattttgtgt ttggaatgtt agaatgagat ctgaatgtgg     5160

tttcaatcta attttttccc agactactat tttctttttt aggtactatt ctgagcatac     5220

tcaacaaaac ccatgcattt cataaactaa tagaagttga ggattgttga atctatttca     5280

cttattttgg ctgtggtttc catctgaaag tagaggttgt atacaccata tactgttctt     5340

cattttatta atatttttct ccttgacctc tcataaattt actttacaca attcttaccc     5400

tgtacatatg taaacataag tgtacgattc ttaaccatgg agtagaggta ctagaatgct     5460

tacggccatc tctttgtaca ggaactgcat tgactttcag taaacataaa gccacaactc     5520

ctacatgatg ttatgtacca tatgatctgt tttgtatctt aaatttgatt tacatatatt     5580

atttatttct ggtaactcac tcagtttatg ctgtgctaaa tatcaatcaa gccatgtata     5640

aatgtgatat gattggcaat atgtgtttac tttaaacttg tcttttcaaa atattactca     5700

gtttatgttg tacaatgtag atggcctctt actaatgtaa aatgatttgt agtggaaaca     5760

tttatatttt tataataaac ataatgaaaa tattttttac agattggaaa aaaaaaaaaa     5820

aaaaaaaaaa aaaaaaa                                                    5837


<210>  448
<211>  2684
<212>  DNA
<213>  homo sapiens

<400>  448
cccgctctgc ttcagcgcac gctgaagacg gcactaggac ccagggaagt ccccgagcgg       60

ggttcgcgga aaggcagcca gactcctcct tatctccagt gtcaaacttg acatcagcct      120

gcgagcggag catggtaact tctccagcaa tcagagcgct ccccctcaca tcagtggcat      180

gcttcatgga gatatgctcc tctcactgcc ctctgcacca gcaacatgga ttgtcagctc      240

tccatcctcc tccttctcag ctgctctgtt ctcgacagct tcggggaact gattccgcag      300

ccttccaatg aagtcaatct actggattca aaaacaattc aaggggagct gggctggatc      360

tcttatccat cacatgggtg ggaagagatc agtggtgtgg atgaacatta cacacccatc      420

aggacttacc aggtgtgcaa tgtcatggac cacagtcaaa acaattggct gagaacaaac      480

tgggtcccca ggaactcagc tcagaagatt tatgtggagc tcaagttcac tctacgagac      540

tgcaatagca ttccattggt tttaggaact tgcaaggaga cattcaacct gtactacatg      600

gagtctgatg atgatcatgg ggtgaaattt cgagagcatc agtttacaaa gattgacacc      660

attgcagctg atgaaagttt cactcaaatg gatcttgggg accgtattct gaagctcaac      720

actgagatta gagaagtagg tcctgtcaac aagaagggat tttatttggc atttcaagat      780

gttggtgctt gtgttgcctt ggtgtctgtg agagtatact tcaaaaagtg cccatttaca      840

gtgaagaatc tggctatgtt tccagacacg gtacccatgg actcccagtc cctggtggag      900

gttagagggt cttgtgtcaa caattctaag gaggaagatc ctccaaggat gtactgcagt      960

acagaaggcg aatggcttgt acccattggc aagtgttcct gcaatgctgg ctatgaagaa     1020

agaggtttta tgtgccaagc ttgtcgacca ggtttctaca aggcattgga tggtaatatg     1080

aagtgtgcta agtgcccgcc tcacagttct actcaggaag atggttcaat gaactgcagg     1140

tgtgagaata attacttccg ggcagacaaa gaccctccat ccatggcttg tacccgacct     1200

ccatcttcac caagaaatgt tatctctaat ataaacgaga cctcagttat cctggactgg     1260

agttggcccc tggacacagg aggccggaaa gatgttacct tcaacatcat atgtaaaaaa     1320

tgtgggtgga atataaaaca gtgtgagcca tgcagcccaa atgtccgctt cctccctcga     1380

cagtttggac tcaccaacac cacggtgaca gtgacagacc ttctggcaca tactaactac     1440

acctttgaga ttgatgccgt taatggggtg tcagagctga gctccccacc aagacagttt     1500

gctgcggtca gcatcacaac taatcaggct gctccatcac ctgtcctgac gattaagaaa     1560

gatcggacct ccagaaatag catctctttg tcctggcaag aacctgaaca tcctaatggg     1620

atcatattgg actacgaggt caaatactat gaaaagcagg aacaagaaac aagttatacc     1680

attctgaggg caagaggcac aaatgttacc atcagtagcc tcaagcctga cactatatac     1740

gtattccaaa tccgagcccg aacagccgct ggatatggga cgaacagccg caagtttgag     1800

tttgaaacta gtccagactg tatgtattat ttcaatgcag tctagaggag ggggcaggga     1860

tcttgcaaaa gatgtctgat cgtttattct cactgtttct aagttttaaa caaatgtgat     1920

acatttaagg tatattgctt gggacattgc aatttgcaga gccctgtgtc tgtatacagt     1980

atttgtgttt gtgtgggtgt acattttgtg tttctttttt tcttgtatgc aaatcaaaca     2040

tattctaatg cctgaaatgc ttctgttttt tttttttagc cataaattgc ttttgaggaa     2100

cattatttaa tatagtaaca cacttccagt gtctgtcatt tcagatattc caggttcatt     2160

gcgtgattca atgaaccaca aaaaagaaac ttgctgatcc atgagaatct taattttgtt     2220

ttaatcctta acacattcaa tagcatatca cagagagaat aaggattttc taaaatgtgt     2280

tttatcactt cattcacatt cagaagtaat ttgaatagcc tgttccttta accccaaatt     2340

tggctaaaat tggcctaaaa ctggcaaaca tttttccagt aacttttctt tttttcaaat     2400

gaattttctt catacttaaa aaagcccttt gctaaaatat aattttcaaa aaggtaaaat     2460

tatgtctatg gcactaatat aaaatgagta gaagttaatg attttactta actcattttt     2520

ttctttcttt cttttttttt tttttttttt gagacggagt cttgctctgt cacccaggct     2580

ggagtacagc agagcgatct cggctcactg caagctcctg caagctccgc ctcctggctt     2640

cacgccattc tccccctcag cctcccgagt agctgggact acag                      2684


<210>  449
<211>  6159
<212>  DNA
<213>  homo sapiens

<400>  449
atggccatag accggcggcg cgaggcggcg ggcggcgggc ctgggcggca gccggccccg       60

gccgaggaga acggctccct gccgcccggg gacgcggcgg cctcggcgcc cctcggggga      120

cgcgcgggcc ccggcggcgg cgcggagatc cagccgctgc ccccactgca tcctggaggc      180

ggcccgcacc cgagctgctg ctccgcggct gcggccccga gcctcttgtt gctggactat      240

gacgggtcgg tgctgccctt cctcgggggc ctgggcgggg gctatcagaa gaccctcgtg      300

ctgctcacct ggatcccggc gctgttcatc ggcttcagcc agttctcgga ctcgttcctc      360

ctggaccagc ccaacttctg gtgccgcggg gccggcaaag gcaccgagct ggcaggggtc      420

accaccacag gccggggcgg ggacatgggc aactggacca gcctccccac cacccccttc      480

gccactgccc cctgggaggc tgcgggcaac cggagcaaca gcagcggcgc ggacggaggc      540

gacacaccac ccctgccatc ccctccggac aagggggaca acgcctccaa ctgtgactgc      600

cgcgcatggg actacggcat ccgcgccggc ctcgtccaga acgtggtcag caagtgggat      660

cttgtgtgtg ataatgcctg gaaggtccat atcgctaagt tctccttact ggttggatta      720

atctttggct acctaataac tggatgcatt gctgactggg tcggccggcg gcctgtgctg      780

ctgttttcca tcatcttcat tctgatcttt ggactgactg tggcactgtc agtgaatgtg      840

acaatgttca gcacactcag gttctttgaa ggattttgcc tggctggaat cattctcacc      900

ttgtatgctt tacgaataga gctgtgcccc cctggaaaac ggttcatgat tacgatggtg      960

gcgagcttcg tggccatggc gggccagttc ctcatgcctg ggctagccgc cctgtgccgg     1020

gattggcagg tgctgcaggc cctcatcatc tgccccttcc tgctcatgct gctctactgg     1080

tcgatattcc ccgagtccct ccggtggcta atggccaccc agcagtttga gtctgcaaag     1140

aggctgatcc tccacttcac acagaagaat cgcatgaacc ctgagggcga catcaagggt     1200

gtgataccag agctggagaa agagctttcc cggaggccca agaaggtctg catcgtgaag     1260

gtggtgggga cacggaacct gtggaagaac attgtggtcc tgtgtgtgaa ctcgctgacg     1320

gggtacggga tccaccactg ctttgccagg agcatgatgg gccacgaggt gaaggtgccg     1380

ctcctggaga acttctatgc tgactactat accacggcca gcatcgcgct ggtgtcctgc     1440

ctggccatgt gcgtggtggt ccgattcctc gggcgcaggg gagggctgct gctcttcatg     1500

atcctcaccg ccctggcctc actcctgcag ctcggcctcc tcaacctgat tggaaagtac     1560

agccagcacc cagactcagg gatgagtgac agcgtcaagg acaaattttc catcgcgttt     1620

tccatcgtgg gcatgtttgc ctcccatgcg gtggggagcc tcagcgtgtt cttctgtgcg     1680

gagatcaccc cgacggtgat aaggtgtggc gggctggggc tggtgctggc cagcgcgggc     1740

ttcggcatgc tgacggcacc catcatcgag ctgcacaacc agaaaggcta cttcctgcac     1800

cacatcatct ttgcctgctg cacgctcatc tgcatcatct gcatcctcct gctgcccgag     1860

agcagggacc agaacctgcc tgagaacatt tctaacgggg agcactacac gcgccagccg     1920

ctgctgccgc acaagaaggg ggagcagcca ctgctgctca ccaacgccga gctcaaggac     1980

tactcgggcc tccacgatgc cgcagccgcg ggtgacacac tgcccgaggg tgccacggcc     2040

aacggcatga aggccatgta gcccggcctg cggaacccgg ggctccaggg tctggggcag     2100

cttgggcaca ggtttacaga ccagggaccg aacacgcagc caggggtggg aaagctgcct     2160

cagccaagct gagcctctca actggtgtgg ggaaatcctg tctttccaaa agtccaagga     2220

gcgcgggtcg gaggagacaa actctttgga aataaccctt tcaagacttt cttttctgcc     2280

gttaaatgtg tgtatttatt ttggtcattt ttacgagaag cactttattc cctctccctc     2340

tcactgatca caaatggaat cacctccctg ggcagcgaga cgcagttgct ctgggaagat     2400

gccacagtga ccagggccat ggccggtccc tctggggaga tgggacacgg ctcctggcag     2460

cacccaggag ccccccaggc tgcctgcctg cgtgcagagg caggagagga ccgtggagcg     2520

tttccgggac tgcattttag acggagtgaa atgtacatga atttggcttt tgctagagtc     2580

tgtgtatggt tttttaaggt cctttttccc tttctgtttg taaggtaaga gcttctgttc     2640

gtgtgcaggg aaagcagctc acagacgccg ttaaaaccag cttcatcttt ccttcaggat     2700

catccttttg tacttgatgc tggaagctct tggagaaaaa gcttaaacat ttcaccagaa     2760

atcttaattg agcagcagtc atatcgccac agctttgtga gtacacagct aacagatgcg     2820

tcgagacctg agatgtgctc gtttttattc ctcctctccc agattggctc cagcagaaaa     2880

gtccctcgtg cacaggcagc tcttgtgccg gcactacttg aaaacatggc tactttctaa     2940

gctacaaacc attagaaaat aactcaaaaa gatggcagag gcaaatccac agaagggggg     3000

ctgccctcca cacacacacg cccgtcaccc acaccttgag cacacaccat gaagatcacc     3060

agcttggatg gccgtcacct cagacatcac tccagggagc acccgcagga gctgggcccc     3120

ctcacgcctg ccttcctggg ccagcttcct gcttgcagtc actcgcatag cacagaggtg     3180

gggcttcggg cagggagcgg agattcctca taggtgagtc caaatgacct ccagcctctc     3240

gaaggcatca agacaaattg aaagaaagca ataactcacc aaagctcaac gctgcccctg     3300

cctcgacctc catgggtctc ttcgtgttcc tcgtttcacc ccagaaagtg gaggtttcct     3360

cttggcattt tcggaggaaa cttgtaggac acccaaggcg actaagagac agcctccttg     3420

gcaagggcag gcaccacttt gtagcaactt gggcaccagc ttttctggac agcctggctt     3480

cttactggca ttgtccaact catcccttct cgaagcatgt ctttgccatg ggctgtgtcc     3540

ttccagggaa attgtggtct cgggcctggg tgagacaatg aagtgacttc caaccgacag     3600

ttgctagaat tcacagggca gaaaaggggt tgaccttctc cccttctggc tttccacccg     3660

gcctgctgct tgctgtcgcc actcatgtct cctccacatg cggtccacac atcagtaagg     3720

gcctggagat gtgtaaagac acagcaaggg gcaagcagac tcttggccac gtgtttccag     3780

tggctggacc acgccgacac ctgggatctt gagataccca ggaagggagg ctgtctggcc     3840

agcctctccc tgcctccact tgctccacgt ccagctcctc accttccctc ttttttaaag     3900

tcacatttcc atgtttcaac attagtttgc attcaccttt acaaaggcct ttctttagat     3960

ctgtgcagcc tttgcgtgcc aaacttgtga aattcctttt accttttttg gagtacttgc     4020

tataaagcca cctgtcaaca aacccccatt atgtacagaa taggacctat ccagtagcca     4080

ggccagtagg cagttgggga aggtgggaag gatccagcga ggcccctgag cctgcacctg     4140

gacaggtgta cgtctgcacc catcaccctc agcaccaggc caccctgcag tccacttact     4200

gtactgtgtt gtggaaggat atgctaagtg atgaaagttg cgagcagtct cactggtcgt     4260

gtaaactttt tttttttttt ggaaattgaa gctgtagagt gctgcccgaa atctctagga     4320

agttggtggc aagggacagc actcacactc ttctggtcat gatctctgat ctccacctca     4380

aatgacaata aaaaactggt ccaacgaaga cactgctcag cacttcagcc atcaggacta     4440

atccatcgat gactggaaaa gaggctagct ttgaggaaaa cagcctgggc tcttgggagc     4500

agagtccagt gggtgtgagg ctgacttgcc gacggtcggc aggtaatggc tctcagccgg     4560

cgaggcggtc ccacagctct cctcccaggg cagcctgagg aggaggaggc cgggtgcctg     4620

tttggtggca gcttcagcct agggatacct gaagctgttg agcaacacct ttatgaaatg     4680

ttgccagagc agcaacactt ccctgtgggc acagccccgg gaaatccggt accaagtgag     4740

caaggtggca ggacccaccc aagcctgata cgcatctggg cccgccgggc tcagcagggg     4800

aggctgctac ggctgcccac ttcccagcac cgtctgtcac gcttgaaccc ctctgtgctg     4860

ttcccttcct ggctaatagg gagacccttc gcaggcaccc actgtttcaa cttgaccctc     4920

ccaccccctg ctactctcct ccacacaccc ctccgttccg ctagcctacc ctgtcagcct     4980

ttcaataaaa gttatgcaca aatgtgaaca cctgagatgg agctgaacat ttcttcactt     5040

tgttcttttt ctgaagtcaa actcttatca aatgccctaa aattattacc acccaagaga     5100

aacaggaaaa aggttacatg tttttgttta ctgagagtaa gatcacctgc atctggaaga     5160

cgggctggta aattggtttg gctacagaac agaaagaaaa caaaaacaaa cctcgtaagg     5220

gaagtatcac actcagacac caccgcttcc tagagccaaa tgagcaatcc caaactgcaa     5280

gtgccataag tgggcctgtg aggtcacacc gcccggcccg aggtatcgca tgtgcggggg     5340

aggtccacac tacagctgtc ctctcgtcta gaaggcacca cctcgctttc atgtcccgtg     5400

tgttttggaa aagcagtatg gtgtgtcatg tctagcggcg aacacttccc tccctgtcct     5460

tgaggttgta atataaaaac tgtgtttctg tacgtgtggg tgggaattct ctgacggtgc     5520

tcgttcatag cacaagctta cgctgagttc tgaactgtcg ttcacagctg cgtgtctgca     5580

tggtgtcgca tctgttgtac ctttggggaa aatttgtatg taaatgtaca gaaataaaaa     5640

cgttgcccca ttaacagatt tcctctggaa tgtcttccct acctcacctg atggtatcca     5700

ccgaagggca tttcactacc attaatggtg agtaataaaa tcctccgtgt tcattcagac     5760

ctcactgcgt cactactttg aacgcctctg taagctgtgt cttcactcgc cccgaggtgg     5820

gtggagggag gcctctcact ctgcttcgag tcctggtctt aaaggtagtc agaggcagag     5880

gctggattaa acacacactg tttaccaagt gccactctca gaccacctga gagacggggg     5940

ccatcagtaa aattaagagg aatttttttc ccttgttcgt gtatgttctg ctgatccgtg     6000

gcctgaaggt tcctagagac gtcaagaaat gaatatctta cactgtgatt ctgtgaggaa     6060

agactggtaa cccaaaactc tcttctctaa tgtatttttt aacgaaaatg acaatatttc     6120

tttaataaag tatttatacc aaaaaaaaaa aaaaaaaaa                            6159


<210>  450
<211>  5945
<212>  DNA
<213>  homo sapiens

<400>  450
aaacagcccc caccctggaa gcctcaggtg ccttccttcc tccccttggt ggggtgagga       60

cgaccgggat gagtcgtctg agaagcactt tgagggggga ggagctgaag gccacacctg      120

gaagggcgat ttattccttg ggcgctgcca ggtgtctgcc gccttcaccc agaaaccgat      180

gatgttcgga gccaggcttc ttcaaagtct cacagccagc ctaccctcaa agcctgagtg      240

attgtggaag gagccagcgt tcactcagca gaggaacaga gctttcctgc cgcaggctct      300

cagtgaagat ccagggagca gaggcgtggg caaggagcac tgggctcaga tgcaggagaa      360

ccggtttgaa ccctagcact accgcctcta cactgaggaa ccttggggat tactcagccc      420

cctggaacct aatttccaag tgggatcttg tgtgtgataa tgcctggaag gtccatatcg      480

ctaagttctc cttactggtt ggattaatct ttggctacct aataactgga tgcattgctg      540

actgggtcgg ccggcggcct gtgctgctgt tttccatcat cttcattctg atctttggac      600

tgactgtggc actgtcagtg aatgtgacaa tgttcagcac actcaggttc tttgaaggat      660

tttgcctggc tggaatcatt ctcaccttgt atgctttacg aatagagctg tgcccccctg      720

gaaaacggtt catgattacg atggtggcga gcttcgtggc catggcgggc cagttcctca      780

tgcctgggct agccgccctg tgccgggatt ggcaggtgct gcaggccctc atcatctgcc      840

ccttcctgct catgctgctc tactggtcga tattccccga gtccctccgg tggctaatgg      900

ccacccagca gtttgagtct gcaaagaggc tgatcctcca cttcacacag aagaatcgca      960

tgaaccctga gggcgacatc aagggtgtga taccagagct ggagaaagag ctttcccgga     1020

ggcccaagaa ggtctgcatc gtgaaggtgg tggggacacg gaacctgtgg aagaacattg     1080

tggtcctgtg tgtgaactcg ctgacggggt acgggatcca ccactgcttt gccaggagca     1140

tgatgggcca cgaggtgaag gtgccgctcc tggagaactt ctatgctgac tactatacca     1200

cggccagcat cgcgctggtg tcctgcctgg ccatgtgcgt ggtggtccga ttcctcgggc     1260

gcaggggagg gctgctgctc ttcatgatcc tcaccgccct ggcctcactc ctgcagctcg     1320

gcctcctcaa cctgattgga aagtacagcc agcacccaga ctcagggatg agtgacagcg     1380

tcaaggacaa attttccatc gcgttttcca tcgtgggcat gtttgcctcc catgcggtgg     1440

ggagcctcag cgtgttcttc tgtgcggaga tcaccccgac ggtgataagg tgtggcgggc     1500

tggggctggt gctggccagc gcgggcttcg gcatgctgac ggcacccatc atcgagctgc     1560

acaaccagaa aggctacttc ctgcaccaca tcatctttgc ctgctgcacg ctcatctgca     1620

tcatctgcat cctcctgctg cccgagagca gggaccagaa cctgcctgag aacatttcta     1680

acggggagca ctacacgcgc cagccgctgc tgccgcacaa gaagggggag cagccactgc     1740

tgctcaccaa cgccgagctc aaggactact cgggcctcca cgatgccgca gccgcgggtg     1800

acacactgcc cgagggtgcc acggccaacg gcatgaaggc catgtagccc ggcctgcgga     1860

acccggggct ccagggtctg gggcagcttg ggcacaggtt tacagaccag ggaccgaaca     1920

cgcagccagg ggtgggaaag ctgcctcagc caagctgagc ctctcaactg gtgtggggaa     1980

atcctgtctt tccaaaagtc caaggagcgc gggtcggagg agacaaactc tttggaaata     2040

accctttcaa gactttcttt tctgccgtta aatgtgtgta tttattttgg tcatttttac     2100

gagaagcact ttattccctc tccctctcac tgatcacaaa tggaatcacc tccctgggca     2160

gcgagacgca gttgctctgg gaagatgcca cagtgaccag ggccatggcc ggtccctctg     2220

gggagatggg acacggctcc tggcagcacc caggagcccc ccaggctgcc tgcctgcgtg     2280

cagaggcagg agaggaccgt ggagcgtttc cgggactgca ttttagacgg agtgaaatgt     2340

acatgaattt ggcttttgct agagtctgtg tatggttttt taaggtcctt tttccctttc     2400

tgtttgtaag gtaagagctt ctgttcgtgt gcagggaaag cagctcacag acgccgttaa     2460

aaccagcttc atctttcctt caggatcatc cttttgtact tgatgctgga agctcttgga     2520

gaaaaagctt aaacatttca ccagaaatct taattgagca gcagtcatat cgccacagct     2580

ttgtgagtac acagctaaca gatgcgtcga gacctgagat gtgctcgttt ttattcctcc     2640

tctcccagat tggctccagc agaaaagtcc ctcgtgcaca ggcagctctt gtgccggcac     2700

tacttgaaaa catggctact ttctaagcta caaaccatta gaaaataact caaaaagatg     2760

gcagaggcaa atccacagaa ggggggctgc cctccacaca cacacgcccg tcacccacac     2820

cttgagcaca caccatgaag atcaccagct tggatggccg tcacctcaga catcactcca     2880

gggagcaccc gcaggagctg ggccccctca cgcctgcctt cctgggccag cttcctgctt     2940

gcagtcactc gcatagcaca gaggtggggc ttcgggcagg gagcggagat tcctcatagg     3000

tgagtccaaa tgacctccag cctctcgaag gcatcaagac aaattgaaag aaagcaataa     3060

ctcaccaaag ctcaacgctg cccctgcctc gacctccatg ggtctcttcg tgttcctcgt     3120

ttcaccccag aaagtggagg tttcctcttg gcattttcgg aggaaacttg taggacaccc     3180

aaggcgacta agagacagcc tccttggcaa gggcaggcac cactttgtag caacttgggc     3240

accagctttt ctggacagcc tggcttctta ctggcattgt ccaactcatc ccttctcgaa     3300

gcatgtcttt gccatgggct gtgtccttcc agggaaattg tggtctcggg cctgggtgag     3360

acaatgaagt gacttccaac cgacagttgc tagaattcac agggcagaaa aggggttgac     3420

cttctcccct tctggctttc cacccggcct gctgcttgct gtcgccactc atgtctcctc     3480

cacatgcggt ccacacatca gtaagggcct ggagatgtgt aaagacacag caaggggcaa     3540

gcagactctt ggccacgtgt ttccagtggc tggaccacgc cgacacctgg gatcttgaga     3600

tacccaggaa gggaggctgt ctggccagcc tctccctgcc tccacttgct ccacgtccag     3660

ctcctcacct tccctctttt ttaaagtcac atttccatgt ttcaacatta gtttgcattc     3720

acctttacaa aggcctttct ttagatctgt gcagcctttg cgtgccaaac ttgtgaaatt     3780

ccttttacct tttttggagt acttgctata aagccacctg tcaacaaacc cccattatgt     3840

acagaatagg acctatccag tagccaggcc agtaggcagt tggggaaggt gggaaggatc     3900

cagcgaggcc cctgagcctg cacctggaca ggtgtacgtc tgcacccatc accctcagca     3960

ccaggccacc ctgcagtcca cttactgtac tgtgttgtgg aaggatatgc taagtgatga     4020

aagttgcgag cagtctcact ggtcgtgtaa actttttttt ttttttggaa attgaagctg     4080

tagagtgctg cccgaaatct ctaggaagtt ggtggcaagg gacagcactc acactcttct     4140

ggtcatgatc tctgatctcc acctcaaatg acaataaaaa actggtccaa cgaagacact     4200

gctcagcact tcagccatca ggactaatcc atcgatgact ggaaaagagg ctagctttga     4260

ggaaaacagc ctgggctctt gggagcagag tccagtgggt gtgaggctga cttgccgacg     4320

gtcggcaggt aatggctctc agccggcgag gcggtcccac agctctcctc ccagggcagc     4380

ctgaggagga ggaggccggg tgcctgtttg gtggcagctt cagcctaggg atacctgaag     4440

ctgttgagca acacctttat gaaatgttgc cagagcagca acacttccct gtgggcacag     4500

ccccgggaaa tccggtacca agtgagcaag gtggcaggac ccacccaagc ctgatacgca     4560

tctgggcccg ccgggctcag caggggaggc tgctacggct gcccacttcc cagcaccgtc     4620

tgtcacgctt gaacccctct gtgctgttcc cttcctggct aatagggaga cccttcgcag     4680

gcacccactg tttcaacttg accctcccac cccctgctac tctcctccac acacccctcc     4740

gttccgctag cctaccctgt cagcctttca ataaaagtta tgcacaaatg tgaacacctg     4800

agatggagct gaacatttct tcactttgtt ctttttctga agtcaaactc ttatcaaatg     4860

ccctaaaatt attaccaccc aagagaaaca ggaaaaaggt tacatgtttt tgtttactga     4920

gagtaagatc acctgcatct ggaagacggg ctggtaaatt ggtttggcta cagaacagaa     4980

agaaaacaaa aacaaacctc gtaagggaag tatcacactc agacaccacc gcttcctaga     5040

gccaaatgag caatcccaaa ctgcaagtgc cataagtggg cctgtgaggt cacaccgccc     5100

ggcccgaggt atcgcatgtg cgggggaggt ccacactaca gctgtcctct cgtctagaag     5160

gcaccacctc gctttcatgt cccgtgtgtt ttggaaaagc agtatggtgt gtcatgtcta     5220

gcggcgaaca cttccctccc tgtccttgag gttgtaatat aaaaactgtg tttctgtacg     5280

tgtgggtggg aattctctga cggtgctcgt tcatagcaca agcttacgct gagttctgaa     5340

ctgtcgttca cagctgcgtg tctgcatggt gtcgcatctg ttgtaccttt ggggaaaatt     5400

tgtatgtaaa tgtacagaaa taaaaacgtt gccccattaa cagatttcct ctggaatgtc     5460

ttccctacct cacctgatgg tatccaccga agggcatttc actaccatta atggtgagta     5520

ataaaatcct ccgtgttcat tcagacctca ctgcgtcact actttgaacg cctctgtaag     5580

ctgtgtcttc actcgccccg aggtgggtgg agggaggcct ctcactctgc ttcgagtcct     5640

ggtcttaaag gtagtcagag gcagaggctg gattaaacac acactgttta ccaagtgcca     5700

ctctcagacc acctgagaga cgggggccat cagtaaaatt aagaggaatt tttttccctt     5760

gttcgtgtat gttctgctga tccgtggcct gaaggttcct agagacgtca agaaatgaat     5820

atcttacact gtgattctgt gaggaaagac tggtaaccca aaactctctt ctctaatgta     5880

ttttttaacg aaaatgacaa tatttcttta ataaagtatt tataccaaaa aaaaaaaaaa     5940

aaaaa                                                                 5945


<210>  451
<211>  1556
<212>  DNA
<213>  homo sapiens

<400>  451
acttgtttca ctttgttttt ggacatagct gagccatgta cttcaaacag aaggcagcca       60

attactaact tctggttgct aggtgtggct tcctttaaaa tcctataaaa tcagaagccc      120

aagtctccac tgccagtgtg aaatcttcag agaagaattt ctctttagtt ctttgcaaga      180

aggtagagat aaagacactt tttcaaaaat ggcaatggta tcagaattcc tcaagcaggc      240

ctggtttatt gaaaatgaag agcaggaata tgttcaaact gtgaagtcat ccaaaggtgg      300

tcccggatca gcggtgagcc cctatcctac cttcaatcca tcctcggatg tcgctgcctt      360

gcataaggcc ataatggtta aaggtgtgga tgaagcaacc atcattgaca ttctaactaa      420

gcgaaacaat gcacagcgtc aacagatcaa agcagcatat ctccaggaaa caggaaagcc      480

cctggatgaa acactgaaga aagcccttac aggtcacctt gaggaggttg ttttagctct      540

gctaaaaact ccagcgcaat ttgatgctga tgaacttcgt gctgccatga agggccttgg      600

aactgatgaa gatactctaa ttgagatttt ggcatcaaga actaacaaag aaatcagaga      660

cattaacagg gtctacagag aggaactgaa gagagatctg gccaaagaca taacctcaga      720

cacatctgga gattttcgga acgctttgct ttctcttgct aagggtgacc gatctgagga      780

ctttggtgtg aatgaagact tggctgattc agatgccagg gccttgtatg aagcaggaga      840

aaggagaaag gggacagacg taaacgtgtt caataccatc cttaccacca gaagctatcc      900

acaacttcgc agagtgtttc agaaatacac caagtacagt aagcatgaca tgaacaaagt      960

tctggacctg gagttgaaag gtgacattga gaaatgcctc acagctatcg tgaagtgcgc     1020

cacaagcaaa ccagctttct ttgcagagaa gcttcatcaa gccatgaaag gtgttggaac     1080

tcgccataag gcattgatca ggattatggt ttcccgttct gaaattgaca tgaatgatat     1140

caaagcattc tatcagaaga tgtatggtat ctccctttgc caagccatcc tggatgaaac     1200

caaaggagat tatgagaaaa tcctggtggc tctttgtgga ggaaactaaa cattcccttg     1260

atggtctcaa gctatgatca gaagacttta attatatatt ttcatcctat aagcttaaat     1320

aggaaagttt cttcaacagg attacagtgt agctacctac atgctgaaaa atatagcctt     1380

taaatcattt ttatattata actctgtata atagagataa gtccattttt taaaaatgtt     1440

ttccccaaac cataaaaccc tatacaagtt gttctagtaa caatacatga gaaagatgtc     1500

tatgtagctg aaaataaaat gacgtcacaa gacaaaaaaa aaaaaaaaaa aaaaaa         1556


<210>  452
<211>  2551
<212>  DNA
<213>  homo sapiens

<400>  452
gtagggagag aactctggag gaacgctgag ctgagcagca ccgaggacag cgcccggcag       60

cgcccgcgcc caggtctccc tccgcagccc tgactcgcgc acacgctgag cttttgctca      120

ctccccctcg cgcggacaca gacacacgca tattcacaca cccagacaca caccccgctg      180

tacaatggca gaatcccacc tgcagtcatc cctcatcaca gcctcacagt ttttcgagat      240

ctggctccat ttcgacgctg acggaagtgg ttacctggaa ggaaaggagc tgcagaactt      300

gatccaggag ctccagcagg cgcgaaagaa ggctggattg gagttatcac ctgaaatgaa      360

aacttttgtg gatcagtatg ggcaaagaga tgatggaaaa ataggaattg tagagttggc      420

tcacgtatta cccacagaag agaatttcct gctgctcttc cgatgccagc agctgaagtc      480

ctgtgaggaa ttcatgaaga catggagaaa atatgatact gaccacagtg gcttcataga      540

aactgaggag cttaagaact ttctaaagga cctgctagaa aaagcaaaca agactgttga      600

tgacacaaaa ttagccgagt atacagacct aatgctgaaa ctatttgatt caaataatga      660

tgggaagctg gaattaactg agatggccag gttactacca gtgcaggaga attttcttct      720

taaattccag ggaatcaaaa tgtgtgggaa agagttcaat aaggcttttg agctgtatga      780

tcaggacggc aatggataca tagatgaaaa tgaactggat gctttactga aggatctgtg      840

cgagaagaat aaacaggatc tggatattaa taatattaca acatacaaga agaacataat      900

ggctttgtcg gatggaggga agctgtaccg aacggatctt gctcttattc tctgtgctgg      960

ggataactag agttggtggc cgcaaccact tgctagtgat acactgtatc taaaaaataa     1020

ctgtgcacta taagggagta ggctgtattt tcttttatat ctgtaaattt aactgcatat     1080

agataattat ccaggatgtg tggctcattc ttttcagctt gtttctatac tgtttgtaat     1140

atacagtttt tgtaaccata tgattgaaaa gaagaaagtc tatgcttagg ccagtcagta     1200

cacccaattt taaaaaataa catattcttg ctttcacaaa tatagttgaa caagatttcc     1260

ctaaaaattc caccaggatt aatctctaaa attctagtct ctgatttgca aatgcacatt     1320

tgtcactgaa taatggaatt atgtataaca agccaaacat tcttatttta gacaaccata     1380

gaactgtccc acaaaatatt tctaagctta tttctaacta ttaggaggaa tgtgcttttc     1440

catctaaaat actcaccaaa atatagttaa ttgtggcttt atgaagttaa cagtctcatt     1500

acagatttag tttaccaatc aacagcatgt ctactgcttg gatccataca aaactatcgg     1560

ttcaagttga tgtgacaagg gaagggagca ccagatgaca cataaatctg tctgattcta     1620

tgcctgtatt tccaacaaac ttactgtcag agaatatgac ctaaatccat tttctaaact     1680

gttttcatgt gttgcaaatt attctagtca actgctgttt tatgtcatac tctgtgtaat     1740

ctctgattaa atttaatata ctgcatatcc tggtgtctag tttgcatact tcctggattt     1800

tctttctatg tagaactgtt catttccacc aagggtatct gctgcctctg aaaatatttt     1860

tttctagcta taacaactct attttttact acataattaa attttaatgt aaaattcata     1920

gcatcctgat tattgaatgt tatatcatca atacttttgt gtattctgtg gattctatat     1980

ttcatattga gatcagcatt caaaatagtt ctatttctat ctgcaaatag tttcaaatga     2040

gtttaaaaaa ataacatctg aaaagaaatg ctaatgtaat catttatctt atctagcaag     2100

aagattctaa aacattcttt aacatacatc taagtcagtt tcacatattt gtagctagaa     2160

tatcctatac tggttatagt tgatatgtaa cagttggtga ttttagattt ctttgattgt     2220

gaaacaggga gctatgagag atgtgtccat gtgaaattta cagttactgc ctaggagtta     2280

atgatcgttc tgggtcagct tgaatgtccc cattctataa attcaacact tattttctga     2340

attcataaaa ataaccaaaa aatgtgagct ataatgtttc cctcaagaac aaacagaaac     2400

gagatttgcc aaaaactaaa attcaacaaa tgatgttgag tgggagattg gctttgcctt     2460

tagcgtgtaa atggaagcac tgccattaga ctgaatttaa ctactaagaa taaataaaga     2520

agaaaataac cttaaaaaaa aaaaaaaaaa a                                    2551


<210>  453
<211>  5173
<212>  DNA
<213>  homo sapiens

<400>  453
aatcggtggc cgccagacac ccgcggcgaa ggcggctcgg gctcgggctc cggatgtgct       60

aggtgtgggc cggcccccac ccgaccctga caagtgacca tggatcctgg agccgggtca      120

gagacatctc tgactgtcaa tgagcaggtc atcgtgatgt caggtcatga gaccatccga      180

gtgctggaag tcggagtgga tgcccaactc cctgctgagg aagagagcaa aggactggag      240

ggtgtggccg ccgagggctc ccagagcgga gaccctgctg aagccagtca agctgctggt      300

gaagctgggc cagacaacct gggctcctct gcagaggcaa ctgtgaagtc acccccgggg      360

atccctccga gccctgcccc tgccattgcc accttcagcc aagccccaag ccagcctcag      420

gcatcgcaga ccctgacgcc actggctgta caagctgccc cccagtattg caggtcaagt      480

ggctggtcag caggggctgg ccgtgtggac aattcctaca gcaactgtgg ctgccctccc      540

aggactgacc gctgcttctc ctacgggggg agtgttcaag ccacctttag ccggtctcca      600

agcagctgct gtgctgaaca ccgctcttcc ggcaccggta caagctgccg caccagtaca      660

ggcctcctcg acggcccaac cccggccacc agcccagccc cagacgctgt tccagaccca      720

gccgctgctg cagaccacac ctgccatcct cccgcagccc actgctgcca ccgctgctgc      780

ccctaccccc aagccagtgg acaccccccc acagatcacc gtccagcctg caggcttcgc      840

atttagccca ggaatcatca gtgctgcttc cctcggggga cagacccaga tcctggggtc      900

cctcactaca gctccagtca ttaccagcgc cattcccagc atgccaggga tcagcagtca      960

gatcctcacc aatgctcagg gacaggttat tggaaccctt ccatgggtag tgaactcagc     1020

tagtgtggcg gccccagcac cagcccaaag cctgcaggtc caggccgtga ccccccagct     1080

gttgttgaac gcccagggcc aggtgattgc gaccctggct agcagccccc tgcctccacc     1140

tgtggctgtc cggaagccaa gcacacctga gtcccctgct aagagtgagg tgcagcccat     1200

ccagcccaca ccaaccgtgc cccagcctgc tgtggtcatt gccagcccag ctccagccgc     1260

caagccatct gcctctgctc ctatcccaat tacctgctca gagaccccca ccgtcagcca     1320

gttggtgtcc aagccacata ctccaagtct ggatgaggat gggatcaact tagaagagat     1380

ccgggagttt gccaagaact ttaagatccg gcggctctcg ctgggcctta cacagaccca     1440

ggtgggtcag gctctgactg caacggaagg tccagcctac agccagtcag ccatctgccg     1500

gttcgagaag ctagacatca cacccaagag tgcccagaag ctaaagccgg tgctggaaaa     1560

gtggctaaac gaagctgaac tgcggaacca ggaaggccag cagaacctga tggagtttgt     1620

gggaggcgag ccctccaaga aacgcaaacg ccgcacctcc ttcacccccc aggccataga     1680

ggctctcaat gcctattttg agaagaaccc actgcccaca ggccaggaga tcactgaaat     1740

tgctaaggag ctcaactacg accgtgaggt agtgcgggtc tggttctgca atcggcgcca     1800

gacgctcaag aacaccagca agctgaacgt ctttcagatc ccttagggct cagcccctgg     1860

ccctgtgttc tagcactttg tccatttccc gtggcatccg gctgcagcca ctgccatgac     1920

agcacctgtc attttgccac gtgcagctgt gctcacccca ggtcatcaga ctccaccgtg     1980

tgcatgtgca tcaatgtccc tcttttctcc cacacatctc acatcatggg gaggccagag     2040

ggggccacac gagagctcca ggctctgggc tggtcactcc gaagaagagg atttgtgacg     2100

tcacttagag aagcaccttg ctagcatggt ttctgaaggg tgaattctgg tggggaacca     2160

gaaactccct gtctttgggg cagggctaaa gcagctccta aggaccactg gccattagct     2220

cttgcttttg atggcattct ctttccacct tgtcttctcc tttgctcctc tgtgttagtg     2280

tggcaggtat gacaactcat ccagtggaaa cacagcctca cactgccctt ccgcccccca     2340

cactttgcct gcaggtgcac cgaaaggacc tgggagataa aattcaaaaa agtgtgatgt     2400

gctgctcaga aggtcagact ccatgtctgc cttgacctca aggtcagaag gttcccaaac     2460

ccctggggct ggaacatggg atctcctctt ccacctcttc ctggttcctt tgcggggaaa     2520

attgcactaa aacagaacct tttcttaatc catgttggaa ggaagcaaca gtgaactcta     2580

cctgttctgg agttctcctg ggtctgcaga aggttgggaa tttagaaaat aaggctgttc     2640

tttcatattt taatttaatc tctgtcaatg gccatccctc ccacaaaaaa acgtgggtta     2700

agagaacttg cagactggat atgcaagcaa acgggcaact ctggagaaaa ataaggaaag     2760

gaatgctgac tttctctttc tttctcttgt ccccacaccc attcccaacc caatactggg     2820

gccttctcaa aaggagcaaa ttaaacaata aaccagacag caaggccctg ggggaaagga     2880

caacatcctg aaataaatga tggagcccag gaaggtctct tgtggaagtt gacttaactc     2940

taattttctt tgtaacttta agccttggat acgggaggag aaatctcatt ttgtcgagtc     3000

tcagaccatg tctgtgtgta agcaatcccc acagtgtcct ctgagccaag gacaccccca     3060

gatcagattg agttttgctt ctagacgggg tagctatggt accttggggg ttagctctca     3120

tccaagctgt taagtgagtt tccagcctca ctgtggctgg aaagccccta aaattcagta     3180

tgtaactcca ggaagtcagg agagaactga gatttgccta gatgaccaca ggcttgcggt     3240

gtagattatc cctaaagggc cccaagtcac gggggtcaac cacccctgtc ttcagtactc     3300

ttatccttac agaggctggt ctctaacagc tgcctccagt ggacctccca tgatccaccc     3360

tgagggaagg accgtcagct ggggacacat caccacctct gtcagtcact ggtgcagagc     3420

cacctcctag cctagcttcc tctggtgtcc tgtttccttt cccacttact gttggtgcct     3480

cccaggccct gcagtgccag cgtggccacc ctcttggtag cctggccagt aagaggagga     3540

cagttgtgtg ctgaattagc acacgcacgt gcagcgcgca cagacgcgcg cacacacaca     3600

cacatacacg ctctgctgca tttggacaaa ccatgcctgc cagagtgtag cagaggtgag     3660

gaagcaggtg ggcagcttgc ctgacccagc ttttcaggag agcgtgtctc caacagagag     3720

tctccacact ctagttcagg gttatcgacc tgcctcaatg agatgacaga ctcatttggg     3780

aggggtgttg caaacaagtt ttcagtgaga atagttaagt tccagagctt gtaaaggatt     3840

cagtgactga cacttcagta aattaggcca ggcacattgg cttatgcctg taattccaac     3900

actttggaag gccgaggtgg gcggatcatt tgaggtctgg agttcgagac cagcctgacc     3960

aacatggtga aaccccgtct ctactaaaaa tacaaaaatt agccaggtgt ggtagtgcac     4020

atctgtaatc ccagctactt gggaggtgga ggcaggagaa ttgcttgaac cctggaggtt     4080

gcaatgagct gagatcacac tacttcactc cagcctgggt gacagagcaa gactcggtct     4140

caaacaaaca aaaacttatg gcgatgcagg ttttcatgct cagacgcttg cattcaggta     4200

tgctttcttt tttgagagag acaaatgggt cacagctggc accctgggaa tagcacataa     4260

tccagggtgt gtctgtggtg gtggacgtgc aggggaacac catctgtcct gtgtcatgat     4320

gggaaaacaa tcatgaacca ctggtctaaa ttaggcctgg ccatgctttc tcagcccctc     4380

cctcatttaa atttgtcttc ccaaagctga gctaaaacta aaccatttct cctctgctgg     4440

aatgatggat tggtcattca gaggaacaat accaggggtg ggaggtttgc aggctgagtt     4500

ccccaggcat gggggtgcag ggtgtccctg aggtttaccc aaagcacagc tcgctggcct     4560

gtgacctctg cccttcctcc cacagtgtaa gaccccccag gaagcagctg gggcctgaac     4620

ctctcaccta ggaggtaggt ttattttatt ttttgttagc atcaggctct gaaggagttg     4680

gtatacattt tgttttgaaa acatcttctg gacttacacc agagcttagt gtcgtcttta     4740

ctatggaaag agaggagaat ggacagaaat ggtttaactg tgtggagttt tgtttgtttt     4800

gttttaaatg gaagaaagac caaaactttc ctggtggatc agctagggcc tttgaccctg     4860

cattaccacg gcattttatc caggtgaagt ccagggaaag aactcagcca aatggactaa     4920

ggaacacacg agtttggaat gcgagactct gacatttttg tgttcttgga aatccaatta     4980

ccttcccatg cccagatttc cttcctgcct cttggaccag gctctggcac tgaggttctc     5040

actgttccca acacagacaa agcttcctga gggctggagg ggcagcaagg ggagaggaga     5100

atggggaaga agcgcttgat gtagttgtgt ggaataaaca gtattttttc ttttgtaaaa     5160

aaaaaaaaaa aaa                                                        5173


<210>  454
<211>  3796
<212>  DNA
<213>  homo sapiens

<400>  454
ctctggatgg accagaatac gaggaggaag aggtggccat accgttgacc gctcctccaa       60

ctaaccagta agttaagact gctgttcagg aatttgggaa gctggctcca gaaaagaagt      120

ggaaatgaag gggtggtatc acggaaaact tgacagaacg atagcagaag aacgcctcag      180

gcaggcaggg aagtctggca gttatcttat aagagagagt gatcggaggc cagggtcctt      240

tgtactttca tttcttagcc agatgaatgt tgtcaaccat tttaggatta ttgctatgtg      300

tggagattac tacattggtg gaagacgttt ttcttcactg tcagacctaa taggttatta      360

cagtcatgtt tcttgtttgc ttaaaggaga aaaattactt tacccagttg caccaccaga      420

gccagtagaa gatagaaggc gtgtacgagc tattctacct tacacaaaag taccagacac      480

tgatgaaata agtttcttaa aaggagatat gttcattgtt cataatgaat tagaagatgg      540

atggatgtgg gttacaaatt taagaacaga tgaacaaggc cttattgttg aagacctagt      600

agaagaggtg ggccgggaag aagatccaca tgaaggaaaa atatggttcc atgggaagat      660

ttccaaacag gaagcttata atttactaat gacagttggt caagtctgca gttttcttgt      720

gaggccctca gataatactc ctggcgatta ttcactttat ttccggacca atgaaaatat      780

tcagcgattt aaaatatgtc caacgccaaa caatcagttt atgatgggag gccggtatta      840

taacagcatt ggggacatca tagatcacta tcgaaaagaa cagattgttg aaggatatta      900

tcttaaggaa cctgtaccaa tgcaggatca agaacaagta ctcaatgaca cagtggatgg      960

caaggaaatc tataatacca tccgtcgtaa aacaaaggat gccttttata aaaacattgt     1020

taagaaaggt tatcttctga aaaagggcaa aggaaaacgt tggaaaaatt tatattttat     1080

cttagagggt agtgatgccc aacttattta ttttgaaagc gaaaaacgag ctaccaaacc     1140

aaaaggatta atagatctca gtgtatgttc tgtctatgtc gttcatgata gtctctttgg     1200

caggccaaac tgttttcaga tagtagttca gcactttagt gaagaacatt acatctttta     1260

ctttgcagga gaaactccag aacaagcaga ggattggatg aaaggtctgc aggcattttg     1320

caatttacgg aaaagtagtc cagggacatc caataaacgc cttcgtcagg tcagcagcct     1380

tgttttacat attgaagaag cccataaact cccagtaaaa cattttacta atccatattg     1440

taacatctac ctgaatagtg tccaagtagc aaaaactcat gcaagggaag ggcaaaaccc     1500

agtatggtca gaagagtttg tctttgatga tcttcctcct gacatcaata gatttgaaat     1560

aactcttagt aataaaacaa agaaaagcaa agatcctgat atcttattta tgcgctgcca     1620

gttgagccga ttacagaaag ggcatgccac agatgaatgg tttctgctca gctcccatat     1680

accattaaaa ggtattgaac cagggtccct gcgtgttcga gcacgatact ctatggaaaa     1740

aatcatgcca gaagaagagt acagtgaatt taaagagctt atactgcaaa aggaacttca     1800

tgtagtctat gctttatcac atgtatgtgg acaagaccga acactactgg ccagcatcct     1860

actgaggatt tttcttcacg aaaagcttga atcgttgttg ttatgcacac taaatgacag     1920

agaaataagc atggaagatg aagccactac cctatttcga gccacaacac ttgcaagcac     1980

cttgatggag cagtatatga aagccactgc tacacagttt gttcatcatg ctttgaaaga     2040

ctctatttta aagataatgg aaagcaagca gtcttgtgag ttaagtccat caaagttaga     2100

aaaaaatgaa gatgtgaaca ctaatttaac acacctattg aacatacttt cagagcttgt     2160

ggagaaaata ttcatggctt cagaaatact tccaccgaca ttgagatata tttatgggtg     2220

tttacagaaa tctgttcagc ataagtggcc tacaaatacc accatgagaa caagagttgt     2280

tagtggtttt gtttttcttc gactcatctg tcctgccatc ctgaatccac ggatgttcaa     2340

tatcatctca gattctccat ctcctattgc tgcaagaaca ctgatattag tggctaaatc     2400

tgtgcagaac ttagcaaatc ttgtggaatt tggagctaag gagccctaca tggaaggtgt     2460

caatccattc atcaaaagca acaaacatcg tatgatcatg tttttagatg aacttgggaa     2520

tgtacctgaa cttccggaca ctacagagca ttctagaacg gacctgtccc gtgatttagc     2580

agcattgcat gagatttgcg tggctcattc agatgaactt cgaacgctca gtaatgagcg     2640

tggtgcacag cagcacgtat tgaaaaagct tctggctata acagaactgc ttcaacaaaa     2700

acaaaaccag tatacaaaaa ccaatgatgt caggtagcag ccttcgcccc agtgttctgc     2760

atggattcag catgtccaac atggtaattc acttcagttt aatgtctcct ttgctcttgc     2820

caaaaaatag cacacttttc cacattccag tgatgtgtga gctatgcaaa caaaatccaa     2880

gattctgctg gtgaataact atgccagcaa ccttgtaagc tatctgtgca ggatatttgc     2940

actatttcca catggaatca atctttaaca acctctgagc cttggtgtac agaccacctt     3000

tcacaaaacg aaatgctatg actgtatctt gatatctcga actttcaaaa tatattttca     3060

gtacacccag ttgccaaagt tttgctgtct cttagagaaa gaactatgaa atcaactgac     3120

aagaaacaca ttcttattga caattgtgta taactggatt gcagactgtt cttactgtaa     3180

ctacttcctg attaggaata tgaccatttg actgttcaat gattatttgt atttacagtt     3240

tccagagttt gtcattataa taggaacaat ctttgctgta tacttttaaa aaatactctg     3300

ctatttctct tgctggaact gttgaaagaa aatatataga atgatctatt gctcatcagc     3360

tttatttttt aaacatacga cttattttgt tgaaattgtc aaagactgta tttagatctc     3420

ataatgcttt gttaaatgtt tacaagtaaa tagtttgaat tcagtaaata ttattggttg     3480

ttgtattgat caatgcatgt tacccattca accattttat agactaccaa tttcttttat     3540

gttaactaga atgcttttgt taaaagttat ttgttcatta tttgtgctac ccctttgatt     3600

atgcagacaa cctcatcagc tgcctaactt atccatcttt gaacttctga ctacttgttg     3660

tatctgctgg atatttagtt caactgtata gttttattta cttctgtatg tgtatttttg     3720

tgaagtattc acaaaggtta agttaaaata aaaccaaggg atatcttgca taattgatta     3780

aaaaaaaaaa aaaaaa                                                     3796


<210>  455
<211>  7331
<212>  DNA
<213>  homo sapiens

<400>  455
gttgtgagct gcggcagaga ctggtggctg gaggagacgc cggcgctgga gagtgcgctg       60

cgccgcccgc cgctgaggga ccgcggggtt agccactgct ggctgcttcc agtgttcgcc      120

gagaggtacc gggggtgaca gctccgggac cggccgaaag gcgaggaacc ggtgtggaaa      180

ttaaaagaac acacatattt tgactggggc tttgatcaac caaatgctaa aaagccacat      240

aaagaagatc cctaatagtc atttctcaac aattatatag tcaactgatg taacaatggt      300

actaatattg ggacgcagac taaacagaga ggatcttggg gtgcgtgatt ccccagcaac      360

taagcgaaaa gtttttgaaa tggaccccaa atctctgaca ggtcatgagt tttttgactt      420

ctcttcagga tcatcccatg ccgaaaacat actccagata tttaatgaat ttcgtgatag      480

ccgcttattc acagatgtta tcatttgtgt ggaaggaaaa gaatttcctt gccatagagc      540

tgtgctctca gcctgtagca gctacttcag agctatgttt tgtaatgacc acagggaaag      600

ccgagaaatg ttggttgaga tcaatggtat tttagctgaa gctatggaat gttttttgca      660

gtatgtttat actggaaagg tgaagatcac tacagagaat gtacagtatc tctttgagac      720

atcaagcctc tttcagatta gtgttctccg tgatgcatgt gccaagttct tggaggagca      780

acttgatcct tgtaattgct taggaatcca gcgctttgct gatacccatt cactcaaaac      840

actcttcaca aaatgcaaaa attttgcgtt acagactttt gaggatgtat cccagcacga      900

agaatttctt gagcttgaca aagatgaact tattgattat atttgtagtg atgaacttgt      960

tattggtaaa gaggagatgg tttttgaagc cgtcatgcgt tgggtctatc gtgccgttga     1020

tctgagaaga ccactgttac acgagctcct gacacatgtg agactccctc tgttgcatcc     1080

caactacttt gttcaaacag ttgaagtgga ccaattgatc cagaattctc ctgagtgtta     1140

tcagttgttg catgaagcaa gacggtacca catacttggg aatgaaatga tgtccccaag     1200

gactaggcca cgcaggtcca ctggctattc tgaggtgata gttgtcgttg gaggatgtga     1260

gcgagttgga ggatttaatc ttccatacac tgagtgctac gatcctgtaa caggagaatg     1320

gaagtctttg gctaagcttc cagaatttac caaatcagag tatgcagtct gtgctctaag     1380

gaatgacatt cttgtttcag gtggaagaat caacagccgt gatgtctgga tttataactc     1440

acagttaaat atttggatca gagttgcctc tctcaataaa ggcagatggc gtcacaaaat     1500

ggctgtcctc cttggtaaag tatatgttgt cggtggctat gatgggcaaa acagacttag     1560

cagcgtagaa tgttatgatt ccttttcaaa tcgatggact gaagttgctc cccttaagga     1620

agccgtgagt tctcctgcag tgactagctg tgtaggcaaa ctgtttgtga ttggtggagg     1680

acctgatgat aatacttgtt ctgataaggt tcaatcttat gatccagaaa ccaattcttg     1740

gctacttcgt gcagctatcc caattgccaa aaggtgtata acagctgtat ccctaaacaa     1800

cctgatctat gttgccggtg gactgaccaa ggcaatatac tgttacgatc cagttgaaga     1860

ttactggatg cacgtacaga atacattcag ccgtcaggaa aactgtggta tgtctgtgtg     1920

taatggtaaa atatatatcc tgggcggaag acgggaaaat ggagaagcca cagacactat     1980

tctctgttat gatcctgcaa caagtatcat cacaggggta gctgcaatgc ccaggccagt     2040

gtcctatcat ggctgtgtga ctattcatag atacaatgag aaatgcttta aactctgaag     2100

acaggatacc tcaccgaaga agccacactg atccaagatg ggaggtttta aaaactctac     2160

agtgggaact tcacatatct cctttgtgcc atatgcaaaa aatagtaaaa ataataattt     2220

ggtgcctttc tcctcaaaat atcaatcttt caaactataa taaagccttt cctataattg     2280

aaaaaaaaaa cttttttgtt aaaggtaatg gtggttgtta cttggccttt gaagagtgta     2340

cctttgtaag tatttgtaag aagtctatgt gaattaggaa atgtctgtct gcataccttt     2400

taggagcgtg tgaatggtgt cttcacttat tatgtatgtt tatctgtatg tatattcctt     2460

attttgtcat atatgtagag aaaattgcat gacttgaggc atcatttagg ttgaagaagt     2520

taatgcttag gatgcattct aggagaaaaa atcagtttta aaaacctttg ttgttaacaa     2580

agtatatcca gattggttaa ttttattgaa gggttttttt ctgtaattga taaaaatgta     2640

atgacaacaa ttcaggcatc ataaaatact gaactattgt gactttattc ttagaattgc     2700

tgtcttacat taaacatgtt tttaggggga agttaggtag gagatagaaa aataagtgcc     2760

cctacaaggg ggattaaaat tacaagttaa ttcctaagag aaaaatggaa tggcctttga     2820

aggaaaaatg acccactatg gctctcaaag tttttatgca tcatctcttc aatcctctaa     2880

gaaagcctct tttcttaact tgataaagca gtggaaaccc attttgcaat attgttttgt     2940

gaaaaacagg gacagacagc caggtacaga gactcacacc tgtactccca actactcagc     3000

aggctggggc aggaggattg cttgagccca ggagtctgag gctacagtga gctatgaacg     3060

cacacggcac cctagcctgg gcaacaggtt gcgacactgt ctcaagagaa aagaaaaaga     3120

aaaataggga taggttttcc ttcctagccc agtagagttt gacctcatta gtatggtgct     3180

ttgggtgagg acctcttcct tgattatccc actttctagt gaacagctaa aattcctgag     3240

agtctctact gttaaggtac ctttaatagg ataaagcagg gaccacctat ctcagtgggt     3300

ccatttttct tttaaaatta gttatctgaa aaaacttagc agtagttccc atctttaagg     3360

taagtctttc atttggtccc cattgtgtaa aatactaatc aacattttca agcttctgta     3420

caacagactg cttttgtcta gatttctcaa ctccacttta taaagcttat cagttttcag     3480

agaggaatgt gaattttttt tctaatgcaa ataaatggat atggcaggaa ctacagcata     3540

agtgattatt gtgattctgg gtggacggat ataatttaca acatttaggg atgttctagg     3600

tagcctgctg tagtttgact tccagtcact gttgtctttc acattataat ttgtatattt     3660

cttgtgatag aagggatgat gcaaatatgt aattaaagtg tcaccagatt tctgttaaaa     3720

ccaaggttga aataaaaagc ctaacattgg taagctacat tgttttctca ttttagaatg     3780

attcagagat ttcagataga cattttttaa actttaatgc ttagctagaa tctacattct     3840

gaggaaaact ctaaaaaact taaaaatttt tagggaattt ttatttttca aatcataatt     3900

ttaaaatgat agataccatt ttgtgataac aacaattcag aaaacaattt tctatcctct     3960

tagttgaaag aatgtaggta cagtttggat acttgtactt taattttaga gtaaacatct     4020

gcattatact cttatagata atagaattat ttagttaaga aattctttac agtaaatgag     4080

ataatgtgtg aaaaagtatt ttgtaaatgc tgaggattct acaaatgata gttgttattt     4140

tcatgtgtat ttgtaagatc atgtccattt catgaatata ggacttcaca taaaaaaaga     4200

ctttctcaag acaactttat attctagtat ttttctgttg taaaaagtat taactattta     4260

cttttatttt gttatacatt tattttaata tccatgtgtt tattatagta aatttgaaat     4320

gaaatcctga aaaacagaat ttttttaaac acagacctca caccaatatt aattttttct     4380

ctacataatt taaaactaca taaattaagt acttaaaatt tatattgaag gccaccaaga     4440

acttaggttg aatcttagaa aatttaaata actattttta aagttaccca acttaatatt     4500

ttaatttttt aatatttatc ttcctttact aattcttgat aaataatagc attagacttg     4560

ataaaataaa aaagaatttt agagtagaat taatatatca aaaggggtat atcaaccaaa     4620

ttggtgtcag attgtattca ttctctcatc acataaagat ttttcttttg ataggtgatg     4680

ctcatatgaa cctttggttt agaatctata tatgtacatg tgtatgtatg tagatagtat     4740

ggttgtatac acacatatat accaaacacc atgaatttta gcagtctgtg atgatcagca     4800

aaaaagcaca taaagtaaaa attagttgac catgctaaat tcaattctgg aatttttttt     4860

tatttgggca tttctagaac tttttacatt tgaaagtaca tgatgagtat tagtaacgat     4920

gacttatgta taatcagaat ctttatgaca atttagtttt acaaggtcag aagagatgag     4980

tttgctaaac ccagctgtga tacctcagtt ggaaagggaa ttcaaaggta tgctttgtag     5040

aacagaaaag tatagttttt ttttcatgaa ctttaatcat tttctgtttt tcctctatgt     5100

gagtcagcta caaaagtggt ctaattttta caacagtaga acttcctcct tttctactgt     5160

aatcttccca ctgactttac tgcacaggta tgaaatacta gtgtattgga tcttcagtaa     5220

cctttttatt tcctagatga ttgaaatata ggtatttact ccatttaaac caggtgataa     5280

gatgatgtaa atactcaggg agggtattaa cttgttactt ttgctcgttt ggggtgtaaa     5340

gtgccatgac tgaataatct tcaattcatg attctagagt aagtttaatt tggaaaaagg     5400

ggcttcacac atggtggtgg ttgaacattg attcttttat acttaaaaag atgaaaatgt     5460

tttgtggact gatacatttt atcttactga atatgaattg tttatgtatc tctactgtca     5520

aatagccttt ttgaaactca ggaaagacaa aggttcaatt acaccacttt tgtcaataag     5580

caaaccaggt attttttttt tctcctgttg tctggatatg gcaatagatt ttttaaattg     5640

ctgtgagaac ccatatatga aaagagagga gttgaattgt gtgtgccttt tatgtcttga     5700

gatttatatg tggaaaagac gacatctact tcaaactgta tttttttcgt tttttttttt     5760

ttttggggaa ggggggagaa cggggtcttg ctctgtcgcc caggctggag tgcagtggcg     5820

cgatctcagc tgactgcaac ctccacctcc cgggttcaag ggattctgcc tcagcctccc     5880

gagtagctga gaccacaggt gcgtgccacc acacccggct aatttttttg tatttttagt     5940

agagacgggg tttagtagag acggatcact cctgaccacg tgatccgccc acctcggcct     6000

cccaaagtgc tgggattaca ggcgtgagcc accacccccg gcctgtattt tcagagagga     6060

gagcttggtg tttttgtggt gccaagtggt aagataatgt ctctttgagg cttcctatgg     6120

actgccttta ttttagtaaa ctcaagacac cagttaacct caacagagtt ttggccttat     6180

tagaatttgt tgtgcatctt attgaaagcc aggtttacat cacctcaccc cattattctt     6240

tttagttaaa taaatttacc atgccaagta accagaatgg agcaaattgg ttgatcttta     6300

aggcagtagg tttgactagc tagctatcat tattgtcaca tctaatgcta ggcaccagaa     6360

accatttgag ccaggagtgt gaatgaataa ttccagagac actttagaca ttttttaatg     6420

ttttatatga acattttaca tttgtgtgat tgccttagat attaaatttt cctagtgctg     6480

ataaaaacag caacattcat aacttatttt atatattgtt ccaaagaaaa gaatttgttt     6540

taatggtttc aaaataactg cacctgaatt tgtttatgtg ccttaagttc tctagtgcta     6600

tttcaacttt tttttcaatc taaatgaagc ttaccttaga taaggttcat atttgtttcc     6660

tatagagtaa ataaacttcc ccttcttaaa ttgtgtaata agcaccaacg tgtggttgct     6720

tggcagaatg agaatgttaa gggagattgt tggatgtttg gagtttcatt atattttttg     6780

tttttatttt ttgataccta ggtgcttttt aaaatattca gacaaatatc tatcttacat     6840

tgattaaacc cgtgtaaatt catttgcagt atctacatcg aatgtcaaaa aagtatactt     6900

atttttgttc catacttatg tacaattttt tccctcttca ggctttttca tttacctttt     6960

tgaaaaagca cttactctcc ccttccctat cacccctccc ccaaggtttc tttatttaaa     7020

tttttattga gagttgttgg agctctaaga caatacaaat ttagagttga acaaaagtat     7080

aatctgcttt acaactagta tagacctaag gtcatttgct ttcaattaga ggctccagag     7140

tcttcatagt ggaaagaatg ctttgtattt aattgttctt agttaagttg tagcacgtga     7200

atacttactt acatgttttg tttaaatata cttcttgcat agtttaattt tttaaaagtt     7260

gtatctaata aaatgtcttt taaccattat tacttgacta tatggttgta ttaaattttg     7320

tttacgaaaa a                                                          7331


<210>  456
<211>  3186
<212>  DNA
<213>  homo sapiens

<400>  456
caggtgatta tcctaattaa tgtctatcta attaaattac tgtcagcagc taaccaatgg       60

caggagccgt ttcatcggct gcacaagcag caagatcaaa agtgagcctt ttctgattgc      120

tgcatagtgt caattggcca atctcttctc ccagggaaaa aaaaaagtaa atcaaacctt      180

tgagaagcat ttgctggttg aagtgctttc tgtctagtga gggggtctgt ggatttctag      240

tttatgataa ataggacttt aaaaaccagg gacgggaggg cgagtgttca ggttctagag      300

ctatgcagct ggagcactgc ctttctcctt ctatcatgct ctccaagaaa tttctcaatg      360

tgagcagcag ctacccacat tcaggcggat ccgagcttgt cttgcacgat catcccatta      420

tctcgaccac tgacaacctg gagagaagtt cacctttgaa aaaaattacc agggggatga      480

cgaatcagtc agatacagac aattttcctg actccaagga ctcaccaggg gacgtccaga      540

gaagtaaact ctctcctgtc ttggacgggg tctctgagct tcgtcacagt ttcgatggct      600

ctgctgcaga tcgctacctc ctctctcagt ccagccagcc acagtctgcg gccactgctc      660

ccagtgccat gttcccgtac cccggccagc acggaccggc gcaccccgcc ttctccatcg      720

gcagccctag ccgctacatg gcccaccacc cggtcatcac caacggagcc tacaacagcc      780

tcctgtccaa ctcctcgccg cagggatacc ccacggccgg ctacccctac ccacagcagt      840

acggccactc ctaccaagga gctccgttct accagttctc ctccacccag ccggggctgg      900

tgcccggcaa agcacaggtg tacctgtgca acaggcccct ttggctgaaa tttcaccggc      960

accaaacgga gatgatcatc accaaacagg gaaggcgcat gtttcctttt ttaagtttta     1020

acatttctgg tctcgatccc acggctcatt acaatatttt tgtggatgtg attttggcgg     1080

atcccaatca ctggaggttt caaggaggca aatgggttcc ttgcggcaaa gcggacacca     1140

atgtgcaagg aaatcgggtc tatatgcatc cggattcccc caacactggg gctcactgga     1200

tgcgccaaga aatctctttt ggaaaattaa aacttacgaa caacaaagga gcttcaaata     1260

acaatgggca gatggtggtt ttacagtcct tgcacaagta ccagccccgc ctgcatgtgg     1320

tggaagtgaa cgaggacggc acggaggaca ctagccagcc cggccgcgtg cagacgttca     1380

ctttccctga gactcagttc atcgccgtca ccgcctacca gaacacggat attacacaac     1440

tgaaaataga tcacaaccct tttgcaaaag gatttcggga taattatgac acgatctaca     1500

ccggctgtga catggaccgc ctgaccccct cgcccaacga ctcgccgcgc tcgcagatcg     1560

tgcccggggc ccgctacgcc atggccggct ctttcctgca ggaccagttc gtgagcaact     1620

acgccaaggc ccgcttccac ccgggcgcgg gcgcgggccc cgggccgggt acggaccgca     1680

gcgtgccgca caccaacggg ctgctgtcgc cgcagcaggc cgaggacccg ggcgcgccct     1740

cgccgcaacg ctggtttgtg acgccggcca acaaccggct ggacttcgcg gcctcggcct     1800

atgacacggc cacggacttc gcgggcaacg cggccacgct gctctcttac gcggcggcgg     1860

gcgtgaaggc gctgccgctg caggctgcag gctgcactgg ccgcccgctc ggctactacg     1920

ccgacccgtc gggctggggc gcccgcagtc ccccgcagta ctgcggcacc aagtcgggct     1980

cggtgctgcc ctgctggccc aacagcgccg cggccgccgc gcgcatggcc ggcgccaatc     2040

cctacctggg cgaggaggcc gagggcctgg ccgccgagcg ctcgccgctg ccgcccggcg     2100

ccgccgagga cgccaagccc aaggacctgt ccgattccag ctggatcgag acgccctcct     2160

cgatcaagtc catcgactcc agcgactcgg ggatttacga gcaggccaag cggaggcgga     2220

tctcgccggc cgacacgccc gtgtccgaga gttcgtcccc gctcaagagc gaggtgctgg     2280

cccagcggga ctgcgagaag aactgcgcca aggacattag cggctactat ggcttctact     2340

cgcacagcta ggccgcccct gcccgcccgg ccccgccgcg gcccggaccc ccagccagcc     2400

cctcacagct cttccccagc tccgcctccc cacactcctc cttgcgcacc cactcatttt     2460

atttgaccct cgatggccgt ctgcagcgaa taagtgcagg tctccgagcg tgattttaac     2520

cttttttgca cagcagtctc tgcaattagc tcaccgacct tcaactttgc tgtaaacctt     2580

ttggttttcc tacttactct tcttctgtgg agttatcctc ctacaattcc cctccccctc     2640

gtctttctct tacctcctac ttctctttct tgtaatgaaa ctcttcacct ttaggagacc     2700

tgggcagtcc tgtcaggcag cagcgattcc gacccgccaa gtctcggcct ccacattaac     2760

cataggatgt tgactctaga acctggaccc acccagcgcg tcctttctta tccccgagtg     2820

gatggatgga tggatggatg gtagggatgt taataatttt agtggaacaa agcctgtgaa     2880

atgattgtac atagtgttaa tttattgtaa cgaatggcta gtttttattc tcgtcaaggc     2940

acaaaaccag ttcatgctta accttttttt cctttccttt ctttgctttt ctttctctcc     3000

tctcatactt tctcttctct ctcttttaat tttcttgtga gataatattc taagaggctc     3060

tagaaacatg aaatactcag tagtgatggg tttcccactt ctcctcaatc cgttgcatga     3120

aataattact atgtgcccta atgcacacaa atagctaagg agaatccacc caaacacctt     3180

taaagg                                                                3186


<210>  457
<211>  6883
<212>  DNA
<213>  homo sapiens

<400>  457
accctctttt cttatcattg acatttaaac tctggggcag gtcctcgcgt agaacgcggc       60

tgtcagatct gccacttccc ctgccgagcg gcggtgagaa gtgtgggaac cggcgctgcc      120

aggctcacct gcctccccgc cctccgctcc caggaatctg agaattgctc tcacacacca      180

acccagcaac atccgtggag aaaactctca ccagcaactc ctttaaaaca ccgtcatttc      240

aaaccattgt ggtcttcaag caacaacagc agcacaaaaa accccaacca aacaaaactc      300

ttgacagaag ctgtgacaac cagaaaggat gcctcataaa gggggaagac tttaactagg      360

ggcgcgcaga tgtgtgaggc cttttattgt gagagtggac agacatccga gatttcagag      420

ccccatattc gagccccgtg gaatcccgcg gcccccagcc agagccagca tgcagaacag      480

tcacagcgga gtgaatcagc tcggtggtgt ctttgtcaac gggcggccac tgccggactc      540

cacccggcag aagattgtag agctagctca cagcggggcc cggccgtgcg acatttcccg      600

aattctgcag gtgtccaacg gatgtgtgag taaaattctg ggcaggtatt acgagactgg      660

ctccatcaga cccagggcaa tcggtggtag taaaccgaga gtagcgactc cagaagttgt      720

aagcaaaata gcccagtata agcgggagtg cccgtccatc tttgcttggg aaatccgaga      780

cagattactg tccgaggggg tctgtaccaa cgataacata ccaagcgtgt catcaataaa      840

cagagttctt cgcaacctgg ctagcgaaaa gcaacagatg ggcgcagacg gcatgtatga      900

taaactaagg atgttgaacg ggcagaccgg aagctggggc acccgccctg gttggtatcc      960

ggggacttcg gtgccagggc aacctacgca agatggctgc cagcaacagg aaggaggggg     1020

agagaatacc aactccatca gttccaacgg agaagattca gatgaggctc aaatgcgact     1080

tcagctgaag cggaagctgc aaagaaatag aacatccttt acccaagagc aaattgaggc     1140

cctggagaaa gagtttgaga gaacccatta tccagatgtg tttgcccgag aaagactagc     1200

agccaaaata gatctacctg aagcaagaat acaggtatgg ttttctaatc gaagggccaa     1260

atggagaaga gaagaaaaac tgaggaatca gagaagacag gccagcaaca cacctagtca     1320

tattcctatc agcagtagtt tcagcaccag tgtctaccaa ccaattccac aacccaccac     1380

accggtttcc tccttcacat ctggctccat gttgggccga acagacacag ccctcacaaa     1440

cacctacagc gctctgccgc ctatgcccag cttcaccatg gcaaataacc tgcctatgca     1500

acccccagtc cccagccaga cctcctcata ctcctgcatg ctgcccacca gcccttcggt     1560

gaatgggcgg agttatgata cctacacccc cccacatatg cagacacaca tgaacagtca     1620

gccaatgggc acctcgggca ccacttcaac aggactcatt tcccctggtg tgtcagttcc     1680

agttcaagtt cccggaagtg aacctgatat gtctcaatac tggccaagat tacagtaaaa     1740

aaaaaaaaaa aaaaaaaaag gaaaggaaat attgtgttaa ttcagtcagt gactatgggg     1800

acacaacagt tgagctttca ggaaagaaag aaaaatggct gttagagccg cttcagttct     1860

acaattgtgt cctgtattgt accactgggg aaggaatgga cttgaaacaa ggacctttgt     1920

atacagaagg cacgatatca gttggaacaa atcttcattt tggtatccaa acttttattc     1980

attttggtgt attatttgta aatgggcatt tgtatgttat aatgaaaaaa agaacaatgt     2040

agactggatg gatgtttgat ctgtgttggt catgaagttg tttttttttt ttttaaaaag     2100

aaaaccatga tcaacaagct ttgccacgaa tttaagagtt ttatcaagat atatcgaata     2160

cttctaccca tctgttcata gtttatggac tgatgttcca agtttgtatc attcctttgc     2220

atataattaa acctggaaca acatgcacta gatttatgtc agaaatatct gttggttttc     2280

caaaggttgt taacagatga agtttatgtg caaaaaaggg taagatataa attcaaggaa     2340

gaaaaaaagt tgatagctaa aaggtagagt gtgtcttcga tataatccaa tttgttttat     2400

gtcaaaatgt aagtatttgt cttccctaga aatcctcaga atgatttcta taataaagtt     2460

aatttcattt atatttgaca agaatataga tgttttatac acattttcat gcaatcatac     2520

gtttcttttt tggccagcaa aagttaattg ttcttagata tagttgtatt actgttcacg     2580

gtccaatcat tttgtgcatc tagagttcat tcctaatcaa ttaaaagtgc ttgcaagagt     2640

tttaaactta agtgttttga agttgttcac aactacatat caaaattaac cattgttgat     2700

tgtaaaaaac catgccaaag cctttgtatt tcctttatta tacagttttc tttttaacct     2760

tatagtgtgg tgttacaaat tttatttcca tgttagatca acattctaaa ccaatggtta     2820

ctttcacaca cactctgttt tacatcctga tgatccttaa aaaataatcc ttatagatac     2880

cataaatcaa aaacgtgtta gaaaaaaatt ccacttacag cagggtgtag atctgtgccc     2940

atttataccc acaacatata tacaaaatgg taacatttcc cagttagcca tttaattcta     3000

aagctcaaag tctagaaata atttaaaaat gcaacaagcg attagctagg aattgttttt     3060

tgaattagga ctggcatttt caatctgggc agatttccat tgtcagccta tttcaacaat     3120

gatttcactg aagtatattc aaaagtagat ttcttaaagg agactttctg aaagctgttg     3180

cctttttcaa ataggccctc tcccttttct gtctccctcc cctttgcaca agaggcatca     3240

tttcccattg aaccactaca gctgttccca tttgaatctt gctttctgtg cggttgtgga     3300

tggttggagg gtggaggggg gatgttgcat gtcaaggaat aatgagcaca gacacatcaa     3360

cagacaacaa caaagcagac tgtgactggc cggtgggaat taaaggcctt cagtcattgg     3420

cagcttaagc caaacattcc caaatctatg aagcagggcc cattgttggt cagttgttat     3480

ttgcaatgaa gcacagttct gatcatgttt aaagtggagg cacgcagggc aggagtgctt     3540

gagcccaagc aaaggatgga aaaaaataag cctttgttgg gtaaaaaagg actgtctgag     3600

actttcattt gttctgtgca acatataagt caatacagat aagtcttcct ctgcaaactt     3660

cactaaaaag cctgggggtt ctggcagtct agattaaaat gcttgcacat gcagaaacct     3720

ctggggacaa agacacactt ccactgaatt atactctgct ttaaaaaaat ccccaaaagc     3780

aaatgatcag aaatgtagaa attaatggaa ggatttaaac atgaccttct cgttcaatat     3840

ctactgtttt ttagttaagg aattacttgt gaacagataa ttgagattca ttgctccggc     3900

atgaaatata ctaataattt tattccacca gagttgctgc acatttggag acaccttcct     3960

aagttgcagt ttttgtatgt gtgcatgtag ttttgttcag tgtcagcctg cactgcacag     4020

cagcacattt ctgcagggga gtgagcacac atacgcactg ttggtacaat tgccggtgca     4080

gacatttcta cctcctgaca ttttgcagcc tacattccct gagggctgtg tgctgaggga     4140

actgtcagag aagggctatg tgggagtgca tgccacagct gctggctggc ttacttcttc     4200

cttctcgctg gctgtaattt ccaccacggt caggcagcca gttccggccc acggttctgt     4260

tgtgtagaca gcagagactt tggagacccg gatgtcgcac gccaggtgca agaggtggga     4320

atgggagaaa aggagtgacg tgggagcgga gggtctgtat gtgtgcactt gggcacgtat     4380

atgtgtgctc tgaaggtcag gattgccagg gcaaagtagc acagtctggt atagtctgaa     4440

gaagcggctg ctcagctgca gaagccctct ggtccggcag gatgggaacg gctgccttgc     4500

cttctgccca caccctaggg acatgagctg tccttccaaa cagagctcca ggcactctct     4560

tggggacagc atggcaggct ctgtgtggta gcagtgcctg ggagttggcc ttttactcat     4620

tgttgaaata atttttgttt attatttatt taacgataca tatatttata tatttatcaa     4680

tggggtatct gcagggatgt tttgacacca tcttccagga tggagattat ttgtgaagac     4740

ttcagtagaa tcccaggact aaacgtctaa attttttctc caaacttgac tgacttggga     4800

aaaccaggtg aatagaataa gagctgaatg ttttaagtaa taaacgttca aactgctcta     4860

agtaaaaaaa tgcattttac tgcaatgaat ttctagaata tttttccccc aaagctatgc     4920

ctcctaaccc ttaaatggtg aacaactggt ttcttgctac agctcactgc catttcttct     4980

tactatcatc actaggtttc ctaagattca ctcatacagt attatttgaa gattcagctt     5040

tgttctgtga atgtcatctt aggattgtgt ctatattctt ttgcttattt ctttttactc     5100

tgggcctctc atactagtaa gattttaaaa agccttttct tctctgtatg tttggctcac     5160

caaggcgaaa tatatattct tctctttttc atttctcaag aataaacctc atctgctttt     5220

ttgtttttct gtgttttggc ttggtactga atgactcaac tgctcggttt taaagttcaa     5280

agtgtaagta cttagggtta gtactgctta tttcaataat gttgacggtg actatctttg     5340

gaaagcagta acatgctgtc ttagaaatga cattaataat gggcttaaac aaatgaatag     5400

gggggtcccc ccactctcct tttgtatgcc tatgtgtgtc tgatttgtta aaagatggac     5460

agggaattga ttgcagagtg tcgcttcctt ctaaagtagt tttattttgt ctactgttag     5520

tatttaaaga tcctggaggt ggacataagg aataaatgga agagaaaagt agatattgta     5580

tggtggctac taaaaggaaa ttcaaaaagt cttagaaccc gagcacctga gcaaactgca     5640

gtagtcaaaa tatttatctc atgttaaaga aaggcaaatc tagtgtaaga aatgagtacc     5700

atatagggtt ttgaagttca tatactagaa acacttaaaa gatatcattt cagatattac     5760

gtttggcatt gttcttaagt atttatatct ttgagtcaag ctgataatta aaaaaaatct     5820

gttaatggag tgtatatttc ataatgtatc aaaatggtgt ctatacctaa ggtagcatta     5880

ttgaagagag atatgtttat gtagtaagtt attaacataa tgagtaacaa ataatgtttc     5940

cagaagaaag gaaaacacat tttcagagtg cgtttttatc agaggaagac aaaaatacac     6000

acccctctcc agtagcttat ttttacaaag ccggcccagt gaattagaaa aacaaagcac     6060

ttggatatga tttttggaaa gcccaggtac acttattatt caaaatgcac ttttactgag     6120

tttgaaaagt ttcttttata tttaaaataa gggttcaaat atgcatattc aatttttata     6180

gtagttatct atttgcaaag catatattaa ctagtaattg gctgttaatt ttatagacat     6240

ggtagccagg gaagtatatc aatgacctat taagtatttt gacaagcaat ttacatatct     6300

gatgacctcg tatctctttt tcagcaagtc aaatgctatg taattgttcc attgtgtgtt     6360

gtataaaatg aatcaacacg gtaagaaaaa ggttagagtt attaaaataa taaactgact     6420

aaaatactca tttgaattta ttcagaatgt tcataatgct ttcaaaggac atagcagagc     6480

ttttgtggag tatccgcaca acattattta ttatctatgg actaaatcaa ttttttgaag     6540

ttgctttaaa atttaaaagc acctttgctt aatataaagc cctttaattt taactgacag     6600

atcaattctg aaactttatt ttgaaaagaa aatggggaag aatctgtgtc tttagaatta     6660

aaagaaatga aaaaaataaa cccgacattc taaaaaaata gaataagaaa cctgattttt     6720

agtactaatg aaatagcggg tgacaaaata gttgtctttt tgattttgat cacaaaaaat     6780

aaactggtag tgacaggata tgatggagag atttgacatc ctggcaaatc actgtcattg     6840

attcaattat tctaattctg aataaaagct gtatacagta aaa                       6883


<210>  458
<211>  2660
<212>  DNA
<213>  homo sapiens

<400>  458
agtttctcct ttgttttacg tttgggagga ggtggcattg gaaatagcag agtgcttcgc       60

ggtaacaggg gttggagtgc aatggtgtga tctcagctca ctgcaacccc tgcctcccag      120

gctccagcga tcctcccacc tcagcctcct gaatagctga ccaccagcac actaggcaaa      180

cccaccccac tcacggcctc ccttgggaat tcagacctaa ccatcgctga gctgaaacaa      240

atgtactgag gctggagcct gtgtgaacag aacagaagag gccttcactc tagtagtgct      300

cacagtccag caggtgtttg ctgaagacag cttactcaga tcactactgc ctggaggtgg      360

ttgatatatc ctggtgtaaa ccttcaagaa gggcacaggc aggaaaacat gagccagcaa      420

ctgaagaaac gggcaaagac aagacaccag aaaggcctgg gtggaagagc ccccagtggg      480

gctaagccca ggcaaggcaa gtcaagccaa gacctgcagg cggaaataga acctgtcagc      540

gcggtgtggg ccttatgtga tggctatgtg tgctatgagc ctggccctca ggctctcgga      600

ggggatgatt tctcagactg ttacatagaa tgcgtcataa ggggtgagtt ttctcaaccc      660

atcctggaag aggactcact ttttgagtcc ttggaatacc taaagaaagg atcagaacaa      720

cagctttctc aaaaggtttt cgaagcaagc tcccttgaat gttctttgga atacatgaaa      780

aaaggggtaa agaaagagct tccacaaaag atagttggag agaattcgct tgagtattct      840

gagtacatga caggcaagaa gcttccgcct ggaggaatac ctggcattga cctatcagat      900

cctaaacagc tcgcagaatt tgctagaaag aagcccccca taaataaaga atatgacagt      960

ctgagcgcaa tcgcttgtcc tcagagtgga tgcactagga agttgaggaa tagagctgcc     1020

ctgagaaagc atctcctcat tcatggtccc cgagaccacg tctgtgcgga atgtgggaaa     1080

gcgttcgttg agagctcaaa actaaagaga catttcctgg ttcatactgg agagaagccg     1140

tttcggtgca cttttgaagg gtgcggaaag cgcttctctc tggactttaa tttgcgtacg     1200

cacgtgcgca tccacacggg ggagaaacgt ttcgtgtgtc cctttcaagg ctgcaacagg     1260

aggtttattc agtcaaataa cctgaaagcc cacatcctaa cgcatgcaaa tacgaacaag     1320

aatgaacaag agggaaagta gtcctccaac aggatgaagc agattaacag aagagtgatc     1380

agtgacaaac atgcctcatt gattattgtt tctaggaagg aatttctaaa tcaatattgc     1440

aaccccaaaa gcggttataa tttggtgtta ctaagatgct cctacacttt gtgataccgt     1500

tttaaggaca tggtgcattt ttttttcttt tatttgtttt atttagaact ttttttattt     1560

gttttattta gaactttgtg tgttcttaaa gtgtgcttcc aacaggaagg tcagtgataa     1620

attttcaaaa gcataacctt caatatatta tctgttggat tattggatat aagacttatt     1680

ttcatgtact ataaatatga aaataacttt gatttttaat tgtgtagttt ccatttctta     1740

gcttttgcct tttaaattta tacttcagcc aggcatagtg actgatgcct gtaatcccaa     1800

cactttgttg ggaggccaaa gcaggaggat agcttgaggc caggagttcc agaccagcct     1860

gggcaacata gtgagatcct gtctctacaa aaaaatttgt ttttatttgt atttatatat     1920

ttttattttt gtttttgttg gtaggcgtct cgctctgtca cccaggctgg agtctagtgt     1980

cgtgatcttg gctcactgca acctccacct cccgggttca agtgattctc tggcctcagc     2040

ctcccaagta gctgggacta caggtgtgtg tcaccacgcc cggctaattt ttgtattttt     2100

agtagagatg gggtttcacc atgttggcca ggctagtctc aaactcctga cctccagtga     2160

tctgcccacc tcggcctccc aaagtgctgg gattacaggt gtgagccact gtgcctggcc     2220

ccccacaaca tgtttaaact tagctaggcc tggttgcata cgcctgtgtt cccagctact     2280

caggaggctg aagcaggagg atagcttgag cccaggagtt tgaggctaca gtgagctgtg     2340

attgcaccac tgtactccag actggataac agcaagagcc catcttttaa aaaaagtaaa     2400

aattaaaaat atacttcatg gttcatgtca tagccctaga gaatgaaaaa tttgcagtag     2460

atagtcaata aatgaatcag tagttaaata ttccttaaag tcaactgtat ttcattgtga     2520

tttttgtttt ctttttatca ttgtatcaaa ctatatggaa atcatatggt tagatgtgat     2580

tatttgataa tgttagtcca tttgaatcca ttttagatat ttcacaatta aagaatatga     2640

aacttcagaa aaaaaaaaaa                                                 2660


<210>  459
<211>  2543
<212>  DNA
<213>  homo sapiens

<400>  459
gaggatgggt aacatgcccg aaggcacaga gagtgtcttg gtctgtccgg acgcgtctgt       60

agagttacag gaagagaagg gccgccctcc agagggccgg gagcgcccca gcgcgggtcc      120

ggggtcgagg taaaatgtcg gttccaggac cttaccaggc ggccactggg ccttcctcag      180

caccatccgc acctccatcc tatgaagaga cagtggctgt taacagttat taccccacac      240

ctccagctcc catgcctggg ccaactacgg ggcttgtgac ggggcctgat gggaagggca      300

tgaatcctcc ttcgtattat acccagccag cgcccatccc caataacaat ccaattaccg      360

tgcagacggt ctacgtgcag caccccatca cctttttgga ccgccctatc caaatgtgtt      420

gtccttcctg caacaagatg atcgtgagtc agctgtccta taacgccggt gctctgacct      480

ggctgtcctg cgggagcctg tgcctgctgg ggtgcatagc gggctgctgc ttcatcccct      540

tctgcgtgga tgccctgcag gacgtggacc attactgtcc caactgcaga gctctcctgg      600

gcacctacaa gcgtttgtag gactcagcca gacgtggagg gagccgggtg ccgcaggaag      660

tcctttccac ctctcatcca gcttcacgcc tggtggaggt tctgccctgg tggtctcacc      720

tctccagggg gcccaccttc atgtcttctt ttggggggaa tacgtcgcaa aactaacaaa      780

tctccaaacc ccagaaattg ctgcttggag tcgtgcatag gacttgcaaa gacattcccc      840

ttgagtgtca gttccacggt ttcctgcctc cctgagaccc tgagtcctgc catctaactg      900

tgatcattgc cctatccgaa tatcttcctg tgatctgcca tcagtggctc ttttttcctg      960

cttccatggg cctttctggt ggcagtctca aactgagaag ccacagttgc cttatttttg     1020

aggctgttct gcccagagct cggctgaacc agcctttagt gcctaccatt atcttatccg     1080

tctcttcccg tccctgatga caaagatctt gccttacaga ctttacaggc ttggctttga     1140

gattctgtaa ctgcagactt cattagcaca cagattcact ttaatttctt aatttttttt     1200

ttaaatacaa ggagggggct attaacaccc agtacagaca tatccacaag gtcgtaaatg     1260

catgctagaa aaatagggct ggatcttatc actgccctgt ctccccttgt ttctctgtgc     1320

cagatcttca gtgccccttt ccatacaggg atttttttct catagagtaa ttatatgaac     1380

agtttttatg acctcctttt ggtctgaaat acttttgaac agaatttctt ttttttaaaa     1440

aaaaacagag atggggtctt actatgttgc ccaggctggt gtcgaactcc tgggctcaag     1500

cgatccttct gccttggcct cccgaagtgc tgggattgca ggcataagct accatgctgg     1560

gcctgaacat aatttcaaga ggaggattta taaaaccatt ttctgtaatc aaatgattgg     1620

tgtcattttc ccatttgcca atgtagtctc acttaaaaaa aaaaaaaaga aaaagaaatg     1680

gataatttca tctactgcct ttacttgggg ttaatgtgat tcttaaacac cttcatcatg     1740

gaactctcag agtggggtcc gttttggttt cctggtggtg ggttttgaaa gataagggaa     1800

agcacatttt gagcatgtct gggtaccatg gtgcggatgc ttgggaacca gaactgtttc     1860

agaggaatct aaagtctgat tttagttttc agagacacag cttgttgtaa aacatgagaa     1920

gacatgattt ctaggactca agcagcaagc caggattcta ggttggctgc tgtgtcatct     1980

ttgaagtcaa gacaaagctg ggctcgacct tcaagggtcc tcgttttgat aatacttcag     2040

aatagggaac tcatgtgaat actactatgt agaaataaaa cctagacctt gagcgaacat     2100

ctgtatattg gttgaaaacg atagtggtaa ccattgatcc cccttcattt gatgtttgga     2160

aaattccagt aattatcatt tttgcaacga atatggatac cacatagtac tttggtgtta     2220

cctgcttttg aaaaataaag tctttggttc acccggtgaa ctatttatga gttcttttgg     2280

tgtgaagaaa gggctcatgt tgcatttcca gccattgcta caaagaacct ttatttgttc     2340

agtaacggta gaaaatcctt cccgattaaa aacttcagac ttgctgaata tcctgcaatg     2400

tcaagatgac cgatgttgag ttgggtggat ttgctaacga gtcagatttg aacatgaggc     2460

tattggaacc caataggcgt cattgatggc ggcaagccat agctttcaag ttttaataaa     2520

atgcacaaaa gagaaaaaaa aaa                                             2543


<210>  460
<211>  1620
<212>  DNA
<213>  homo sapiens

<400>  460
actctgacag cgccgaggtg cgccgagcag gagcagggaa caaaggagcg gagaggggag       60

gggagagagt tgggcgaggg agagcccccg gccggctgcc agaagatccc ggcgggagga      120

agcccaagtg tcacttgaat tccacccaag gagcgggcgc ctgggatcag agcgtcctgt      180

ttagcaataa cggctggagc acgtcctaca agttacggga gagtcggctg tgaaggagac      240

gttcgcttat cccctgtgtc cccgctcctg gcccctccag acccccgcct tgcctcgcgc      300

tgggagggga gatccagaat gaaaggcaag aaaggtattg ttgcagcatc tggcagtgag      360

actgaggatg aggacagcat ggacattccc ttggaccttt cttcatccgc tggctcaggc      420

aagagaagga gaaggggcaa cctacccaag gagtctgtgc agattcttcg ggattggctg      480

tatgagcacc gttacaatgc ctatccttca gagcaagaaa aagcgttgct gtcccagcaa      540

acacacctgt ctacgctaca ggtctgtaac tggttcatca acgcccgccg caggctcctc      600

cctgacatgc tgagaaagga tggcaaagat ccaaatcagt tcacaatttc ccgccgtggg      660

gccaagattt ctgaaacgag ctctgtggag tccgtgatgg gcatcaaaaa cttcatgcca      720

gctctagagg agaccccatt tcattcctgt acagctgggc caaacccaac cctagggagg      780

ccactgtctc ctaagccgtc atccccggga tcagttttgg ctcgtccatc agtgatctgc      840

cataccactg tgactgcatt gaaagatgtc cctttctctc tctgccagtc ggtcggtgtg      900

ggacaaaaca cagatataca gcagatagcg gccaaaaact tcacagacac ctctctcatg      960

tacccagagg acacttgtaa atctggacca agtacgaata cacagagtgg tcttttcaac     1020

actcctcccc ctactccacc ggacctcaac caggacttca gtggatttca gcttctagtg     1080

gatgttgcac tcaaacgggc tgcagagatg gagcttcagg caaaacttac agcttaaccc     1140

attttcaagc aaaacagttc tcagaaatgt catgattgcc ggggtgaagg caagagatga     1200

attgcattat tttatatatt ttttattaat atttgcacat gggattgcta aaacagcttc     1260

ctgttactga gatgtcttca atggaataca gtcattccaa gaactataaa cttaaagcta     1320

ctgtagaaac aaagggtttt cttttttaaa tgtttcttgg tagattattc ataatgtgag     1380

atggttccca atatcatgtg attttttttt tcctcccctt cccttttttt gttatttttt     1440

cagactgtgc aatacttaga gaacctatag catcttctca ttcccatgtg gaacaggatg     1500

cccacatact gtctaattaa taaattttcc attttttttc aaacaagtat gaatctagtt     1560

ggttgatgcc ttttttttca tgacataata aagtattttc tttaaaaaaa aaaaaaaaaa     1620


<210>  461
<211>  5090
<212>  DNA
<213>  homo sapiens

<400>  461
gagctccggg tccgcggcgg agcgagcgag cggccggcag gttgggagga gcggccgaag       60

gttgaatgcc tttgagaact tgatgcataa aatttgcatg actcctcact cctttctgga      120

tctctcattg gactcaagcc agcatggctc acaccacaaa ggttaacggc agtgcctcag      180

gaaaagcagg tgatattctc agtggagacc aggacaagga acagaaagac ccttactttg      240

tggagacccc ctatggttat caactagact tagatttcct caaatatgtg gatgacatac      300

agaagggaaa taccatcaaa agactgaaca tccagaagag gcggaagccg tccgtgccat      360

gcccagaacc caggaccaca tctggtcagc aaggtatatg gacttccact gaatccctct      420

catcctccaa cagtgatgac aacaagcagt gccccaactt cctcatagcc agaagtcaag      480

ttacatcaac tccaatctca aagccacctc cccctctgga gacctcactc ccttttctta      540

ccatcccaga aaatcgacag ctgccacctc cctcaccaca actcccaaag cataaccttc      600

atgtcaccaa gacactgatg gagacccgga gaagactgga acaggagaga gccaccatgc      660

agatgacacc gggtgagttc agaaggccca ggctggccag ttttggaggc atgggcacca      720

caagctccct cccttctttt gtgggttctg gaaaccacaa tcctgccaag caccagcttc      780

agaatggata ccaaggtaat ggggattatg gtagctatgc cccagctgct cccaccactt      840

cctccatggg gagctccatc cgccacagcc ccctgagctc agggatctcc accccagtga      900

ccaacgtgag ccccatgcac ctgcagcaca tccgcgagca gatggccatt gctctgaaac      960

gcctgaagga gctggaggag caggtgcgaa ccatccctgt gctccaggta aagatctctg     1020

tcttgcaaga agagaaaagg cagttggtct cacagctgaa aaaccaaagg gctgcatccc     1080

agatcaatgt ctgtggtgtg aggaagcggt cctatagtgc ggggaacgcc tcccagctgg     1140

aacagctctc ccgggcccga agaagtggcg gggaattata cattgactat gaggaggaag     1200

aaatggagac cgtagaacag agcacgcaga ggataaagga gttccggcaa cttacagcag     1260

acatgcaagc cctggagcag aagatccagg acagcagctg tgaggcctcc tcagagctca     1320

gggagaatgg agagtgccgg tctgtggctg tgggtgccga ggagaacatg aacgacatcg     1380

tcgtgtacca cagaggctcc aggtcctgta aggatgcagc tgtagggaca cttgttgaga     1440

tgagaaattg tggggtcagc gtgacagagg ccatgcttgg agtgatgact gaagctgaca     1500

aagaaattga gctgcaacag cagaccatag aatccttgaa ggaaaagatc tatcgcctag     1560

aagtacagct tagagaaacc acccatgacc gggagatgac taaactgaaa caagagctgc     1620

aggctgctgg atcgaggaaa aaggttgaca aagccacgat ggcccagccg cttgttttca     1680

gtaaggtggt ggaggcagtg gtgcagacca gagaccaaat ggtcggcagt cacatggacc     1740

tggtggacac gtgtgttggg acctccgtgg aaacaaacag tgtaggcatc tcctgccagc     1800

ctgaatgtaa gaataaagtc gtagggcctg agctgcctat gaattggtgg attgttaagg     1860

agagggtgga aatgcatgac cgatgtgctg ggaggtctgt ggaaatgtgt gacaagagtg     1920

tgagtgtgga agtcagcgtc tgcgaaacag gcagcaacac agaggagtct gtgaacgacc     1980

tcacactcct caagacaaac ttgaatctca aagaagtgcg gtctatcggt tgtggagatt     2040

gttctgttga cgtgaccgtc tgctctccaa aggagtgcgc ctcccggggc gtgaacactg     2100

aggctgttag ccaggtggaa gctgccgtca tggcagtgcc tcgtactgca gaccaggaca     2160

ctagcacaga tttggaacag gtgcaccagt tcaccaacac cgagacggcc accctcatag     2220

agtcctgcac caacacttgt ctaagcactt tggacaagca gaccagcacc cagactgtgg     2280

agacgcggac agtagctgta ggagaaggcc gtgtcaagga catcaactcc tccaccaaga     2340

cgcggtccat tggtgttgga acgttgcttt ctggccattc tgggtttgac aggccatcag     2400

ctgtgaagac caaagagtca ggtgtggggc agataaatat taacgacaac tatctggttg     2460

gtctcaaaat gaggactata gcttgtgggc caccacagtt gactgtgggg ctgacagcca     2520

gcagaaggag cgtgggggtt ggggatgacc ctgtagggga atctctggag aacccccagc     2580

ctcaagctcc acttggaatg atgactggcc tggatcacta cattgagcgt atccagaagc     2640

tgctggcaga acagcagaca ctgctggctg agaactacag tgaactggca gaagctttcg     2700

gggaacctca ctcacagatg ggctccctca actctcagct catcagcacc ctgtcgtcta     2760

tcaactctgt catgaaatct gcaagcactg aagagctgag gaaccctgac ttccagaaaa     2820

ccagtctggg taaaatcaca ggcaattatt tgggatatac ctgtaagtgt gggggccttc     2880

agtcaggaag tcccttaagc tcccagacat cccagcctga gcaagaagtg gggacctcag     2940

aaggaaagcc aatcagcagc ctggatgcct tccccactca ggaaggtacg ctgtctccag     3000

tgaacctgac agacgaccag atcgccgctg gcctctatgc atgtacaaac aatgaaagta     3060

cactgaagtc catcatgaag aagaaagatg gtaacaaaga ttcaaatggc gcaaaaaaga     3120

atcttcagtt tgttggcatt aatggagggt atgaaacaac ttcaagtgat gattccagct     3180

cagatgaaag ctcttcttcc gagtcagatg acgagtgtga tgtcattgag tatcctcttg     3240

aagaagagga ggaggaggag gatgaagaca ctcggggaat ggcagaaggg caccatgcag     3300

ttaatattga aggtttgaag tctgccaggg tggaagatga aatgcaggtt caagaatgtg     3360

aacctgagaa ggtggaaatc agagagaggt atgaattaag tgaaaagatg ttgtctgcat     3420

gcaacttact gaaaaatact ataaatgacc ccaaagcttt gaccagcaaa gatatgaggt     3480

tctgtctgaa caccctccag cacgagtggt tccgcgtgtc cagtcagaag tcagccattc     3540

cagccatggt gggggactac atagctgctt ttgaggccat ttccccagat gtcctccgct     3600

atgtcatcaa cttggcagac ggcaacggca acacagccct ccattacagc gtgtcccact     3660

ccaacttcga gattgtgaag ctgctgttag atgccgatgt gtgtaatgtg gatcaccaga     3720

acaaggcagg ctacaccccc atcatgttgg cggccctcgc cgctgtggaa gcagagaagg     3780

acatgcggat tgtggaagaa ctcttcggct gtggggatgt gaatgccaaa gctagtcagg     3840

cgggacagac ggccctcatg ctggcggtca gtcacggacg gatagacatg gtgaagggcc     3900

ttctggcctg tggggctgat gtcaacatcc aggatgacga gggctccacg gccctcatgt     3960

gtgccagcga gcacgggcac gtggagattg tcaagctgct gctggcccag cccggctgca     4020

acggtcacct agaggacaac gatggcagca ctgcgctctc aatcgccctg gaagcaggac     4080

acaaggacat cgctgttctt ctgtatgccc atgtcaactt tgcaaaagcc cagtctccgg     4140

gcacccctag gcttggaagg aagacgtctc ctggccccac ccaccgaggt tcatttgatt     4200

gattgtatgc aaatagccct ttatttacat gccactatta agctgctaat tgttcctgtt     4260

ggggtgacag atactgaatg tatacgtatt gtgcctgagc tcaccagcaa acagaagcat     4320

caagcccagg ggtaaaggct gaagctttca cagtgcagag actgctagcc tgggcacaca     4380

cacctccttt ctggccgtct tctgtgtagg gcacacttta acccagtctc tgttgctgtt     4440

gagtctctgc tccgttttgt acagtcacag ggaattctga tctgaagggg caccttctgt     4500

tcactcccac aaagtggtgt ctggttctca ctgagacgtt ttaagatttt tccacaaata     4560

tttatatgta ctaaatgtgg aaccattaga aagttcttcc aaaatctcat tccagcatag     4620

ttttggattt ttcttttgtc ttattttaaa ataaggaagt cgagatgact ttgatcattg     4680

gtaacttggg cctgggccag acaaagtata aaacttacaa aagaatattc tcatttggtc     4740

ttaactaggt agatgtaata tatgactttt tataaaaagg gtatctatat gaacttgaca     4800

cagtattttc agcttttgta ttccatacta aagccatgaa gaactacacg taacatcatc     4860

atttgtatta attgcacaac tccaatgcta aaggttggat tgtgttagag gaatcggctc     4920

tgtatttgcc tctagagaaa cacagtgttc tctttgtatt tatggattcc tttttaccgt     4980

gtcacattta ctttggtcct ctatgtattt aaatgtttga agtgccttag actcttgcca     5040

tattttcaaa ataaaattcc attaagctct tttaaaaaaa aaaaaaaaaa                5090


<210>  462
<211>  2522
<212>  DNA
<213>  homo sapiens

<400>  462
accccaacgc cgcttctgcg gccaaagtag gttgggagtg gaaggtggtg gctgctgctc       60

cgcagtgtcg ggaagatggc gccgccggtg gcagagaggg ggctaaagag cgtcgtgtgg      120

cagaagataa aagcaacagt gtttgatgac tgcaagaaag aaggcgaatg gaagataatg      180

cttttagatg aatttaccac taagcttttg gcatcgtgtt gcaaaatgac agatcttcta      240

gaagaaggta ttactgttgt agagaatatt tataagaacc gtgaacctgt cagacaaatg      300

aaagctcttt atttcatcac tccgacatca aagtctgtag attgtttctt acatgatttt      360

gcaagtaaat cggagaacaa gtataaagca gcatatattt acttcactga cttttgccct      420

gataatctct ttaacaaaat taaggcttct tgctccaagt caataagaag atgtaaagaa      480

ataaatattt ccttcattcc acatgaatct caggtgtata ctcttgatgt accagatgca      540

ttctattact gttatagtcc agaccctggt aatgcaaagg gaaaagatgc cattatggaa      600

acaatggctg accagatagt tacagtgtgt gccaccttgg atgaaaatcc cggagtaaga      660

tataaaagta aacctctaga taatgccagt aagcttgcac agcttgttga aaaaaagctt      720

gaagactact acaagattga tgaaaagagc ctaataaagg gtaaaactca ttcacagctc      780

ttaataattg atcgtggctt tgatcctgtg tccactgtcc tgcatgaact gacctttcag      840

gcaatggcat atgatctact accaattgag aatgatacat acaaatataa aacagatgga      900

aaagaaaagg aggccatcct tgaagaagaa gatgacctct gggttagaat tcgacatcga      960

catattgcgg ttgtgttaga ggaaattccc aagcttatga aagaaatttc atcaacaaag     1020

aaagcaacag aaggaaagac atcacttagt gctcttaccc agctgatgaa aaagatgccc     1080

catttccgaa aacagattac taagcaagtt gtccatctta acttagcaga agattgcatg     1140

aataagttca agcttaatat agaaaagctc tgcaaaactg aacaggacct ggcacttgga     1200

actgatgcag aaggacagaa ggtgaaagat tccatgcgag tactccttcc agttctactc     1260

aacaaaaatc atgataattg tgataaaata agagcaattc tactttatat cttcagtatt     1320

aatggaacta cggaagaaaa tttggacagg ttgatccaga atgtaaagat agaaaatgag     1380

agtgacatga ttcgtaactg gagttacctt ggtgttccca ttgttcccca atctcaacaa     1440

ggcaaaccgt taagaaagga tcggtctgca gaagaaactt ttcagctctc tcggtggaca     1500

ccttttatca aagatattat ggaggatgct attgataata gattagattc aaaagaatgg     1560

ccatattgtt cccagtgtcc agcagtatgg aatggttcag gagctgtaag tgctcgccag     1620

aaacccagag ctaattattt agaagaccga aaaaatgggt caaagctgat tgtttttgta     1680

attggaggga tcacatactc tgaagtgcgt tgtgcttatg aagtttctca ggcacataaa     1740

tcctgtgaag ttattattgg ttctacacat gttttaacac ccaaaaagct gttggatgat     1800

ataaagatgc tgaataaacc caaggataaa gtctccttaa ttaaagatga atagcatttc     1860

tttttggagg gtttagagat tcttactaat atgttgaact aaaatagaaa gaaaatgttg     1920

ctgtcatgta atttaaacaa tgtaaatatt ttatggaata atggcttttc aaatacattt     1980

cttaaggaac tgtttatgat tattactgga tttgtcattt ttgataattt aaatattgct     2040

gctgctttgt agatgatgag aagaaatgtt aaagtgcttt ctaaaaggaa attttttcac     2100

ctttggagga gaatatatta gagttgtggg taatttttca cagccaccta tgtacatact     2160

aattacccat tggatactta tatctaaaag tctcatgctg aagtatagtt tttgggaaag     2220

aatgatttta aataaagaga ttgtaaaagt aaaaaactgt aaatgtatat gtatgataga     2280

attgtttcct ctaagtgtag tttttctttc aactaaaatt cagtttatgt gtaaaataat     2340

tcagtcatta atagaaatgg agtgatttca cagtgtgtac tgttttgcca catacttcta     2400

aagaacacaa ttttatataa ttttgaaatc atgtatgttt aaattagaaa accaaaaatc     2460

atgaacattc taagagaaaa taaatataga atttaaaaaa ttaaaaaaaa aaaaaaaaaa     2520

aa                                                                    2522


<210>  463
<211>  2226
<212>  DNA
<213>  homo sapiens

<400>  463
aaacggagtg ggagaagggg gctagcgagg aggaagaggc gggaggtgcg gcaggggcac       60

aggtgacgct cctcccgcct gcctagcaga gctccaggcg cacatccgca gtcagccacc      120

tcgcgcgcgc ctccaggagc aaggatggag aggctggtga tcaggatgcc cttctctcat      180

ctgtctacct acagcctggt ttgggtcatg gcagcagtgg tgctgtgcac agcacaagtg      240

caagtggtga cccaggatga aagagagcag ctgtacacac ctgcttcctt aaaatgctct      300

ctgcaaaatg cccaggaagc cctcattgtg acatggcaga aaaagaaagc tgtaagccca      360

gaaaacatgg tcaccttcag cgagaaccat ggggtggtga tccagcctgc ctataaggac      420

aagataaaca ttacccagct gggactccaa aactcaacca tcaccttctg gaatatcacc      480

ctggaggatg aagggtgtta catgtgtctc ttcaatacct ttggttttgg gaagatctca      540

ggaacggcct gcctcaccgt ctatgtacag cccatagtat cccttcacta caaattctct      600

gaagaccacc taaatatcac ttgctctgcc actgcccgcc cagcccccat ggtcttctgg      660

aaggtccctc ggtcagggat tgaaaatagt acagtgactc tgtctcaccc aaatgggacc      720

acgtctgtta ccagcatcct ccatatcaaa gaccctaaga atcaggtggg gaaggaggtg      780

atctgccagg tgctgcacct ggggactgtg accgacttta agcaaaccgt caacaaaggc      840

tattggtttt cagttccgct attgctaagc attgtttccc tggtaattct tctcgtccta      900

atctcaatct tactgtactg gaaacgtcac cggaatcagg accgagagcc ctaaataagt      960

cacacagcac cctgaaagtg attccctggt ctacttgaat ttgacacaag agaaaagcag     1020

gaggaaaagg ggccattctc caaaggacct gaaagagcaa aagaggtggg agcgaaagcc     1080

ttaaggatcc cacgactttt tactgccatc tgagctactc agtgtttgaa tcccaagagg     1140

aagtcagttt acctctcagg tctgttgtag gacttgattt tgtaaagcaa tgccatgtta     1200

tgtggttgaa agggcactgg acttagttag tatcaggagc actgagctca cagactgact     1260

tgggctccta ctggtgggga cctctgttag tcactttacc tcatccaaag tataaaggaa     1320

ttggaccaaa taatttacca catagctcta aaacttaatt taaaatgtaa ttccagaaaa     1380

aaaaagggaa taagcaaagg gggaagaatt gaaagagaga gagaagaaag aatacagaga     1440

gcttaccttt tgcctttctg ttgatgttac atctcttctt cctatgttct taggtctatg     1500

agtctgtttc cccatcattt ggtatctagt ccagttcctg cttactgctt tgctaatagc     1560

tggccttgct agaatccttg gtttcactgc tgttcttcat gtgcttctat gagatttact     1620

ccaacacaaa taggactgaa tttattgtga agtaacattg gcaatcttaa cttattcatt     1680

taacttattt ttatagctag ataaatattg ttagtcttag acaatagctc acattttttg     1740

agaagcatgc cctccctgtc catttgtctt ataacatgac ccagccctat tttacgtcat     1800

tctaaattca gcctcatata atgaaaatac attatgaaaa cagatgttta ggagatttcc     1860

tgtatagcag tcagccaatt catatgcttt gtctctgctg gcttcttttt ccatgcgtta     1920

acttttccca atagcagagg aggcaaatat gagcatacaa tccctttgtt ctaaagatat     1980

tgttccagct agtggaatga tgttgaatct ttaataacca taattagttg ctttttcagt     2040

atcttctgct ttgtctgtgt ctatccagtg gcctaggaat taaagtgtaa gttgttttcg     2100

ctgttaaatt ggatatttat atatatatat agcaagattt tcatgtgtta tttaattctg     2160

tattgtttct tatatttgta gtaaaatatt gaacaattaa aagtgttgac tccaaaaaaa     2220

aaaaaa                                                                2226


<210>  464
<211>  2765
<212>  DNA
<213>  homo sapiens

<400>  464
ccggcctcag ggacgcaccg gagccgcctt tccgggcctc aggcggattc tccggcgcgg       60

cccgccccgc ccctcggact ccccgggccg cccccggccc ccattcgggc cgggcctcgc      120

tgcggcggcg actgagccag gctgggccgc gtccctgagt cccagagtcg gcgcggcgcg      180

gcaggggcag ccttccacca cggggagccc agctgtcagc cgcctcacag gaagatgctg      240

cgtcggcggg gcagccctgg catgggtgtg catgtgggtg cagccctggg agcactgtgg      300

ttctgcctca caggagccct ggaggtccag gtccctgaag acccagtggt ggcactggtg      360

ggcaccgatg ccaccctgtg ctgctccttc tcccctgagc ctggcttcag cctggcacag      420

ctcaacctca tctggcagct gacagatacc aaacagctgg tgcacagctt tgctgagggc      480

caggaccagg gcagcgccta tgccaaccgc acggccctct tcccggacct gctggcacag      540

ggcaacgcat ccctgaggct gcagcgcgtg cgtgtggcgg acgagggcag cttcacctgc      600

ttcgtgagca tccgggattt cggcagcgct gccgtcagcc tgcaggtggc cgctccctac      660

tcgaagccca gcatgaccct ggagcccaac aaggacctgc ggccagggga cacggtgacc      720

atcacgtgct ccagctaccg gggctaccct gaggctgagg tgttctggca ggatgggcag      780

ggtgtgcccc tgactggcaa cgtgaccacg tcgcagatgg ccaacgagca gggcttgttt      840

gatgtgcaca gcgtcctgcg ggtggtgctg ggtgcgaatg gcacctacag ctgcctggtg      900

cgcaaccccg tgctgcagca ggatgcgcac ggctctgtca ccatcacagg gcagcctatg      960

acattccccc cagaggccct gtgggtgacc gtggggctgt ctgtctgtct cattgcactg     1020

ctggtggccc tggctttcgt gtgctggaga aagatcaaac agagctgtga ggaggagaat     1080

gcaggagctg aggaccagga tggggaggga gaaggctcca agacagccct gcagcctctg     1140

aaacactctg acagcaaaga agatgatgga caagaaatag cctgaccatg aggaccaggg     1200

agctgctacc cctccctaca gctcctaccc tctggctgca atggggctgc actgtgagcc     1260

ctgcccccaa cagatgcatc ctgctctgac aggtgggctc cttctccaaa ggatgcgata     1320

cacagaccac tgtgcagcct tatttctcca atggacatga ttcccaagtc atcctgctgc     1380

cttttttctt atagacacaa tgaacagacc acccacaacc ttagttctct aagtcatcct     1440

gcctgctgcc ttatttcaca gtacatacat ttcttaggga cacagtacac tgaccacatc     1500

accaccctct tcttccagtg ctgcgtggac catctggctg ccttttttct ccaaaagatg     1560

caatattcag actgactgac cccctgcctt atttcaccaa agacacgatg catagtcacc     1620

ccggccttgt ttctccaatg gccgtgatac actagtgatc atgttcagcc ctgcttccac     1680

ctgcatagaa tcttttcttc tcagacaggg acagtgcggc ctcaacatct cctggagtct     1740

agaagctgtt tcctttcccc tccttcctcc tcttgctcta gccttaatac tggccttttc     1800

cctccctgcc ccaagtgaag acagggcact ctgcgcccac cacatgcaca gctgtgcatg     1860

gagacctgca ggtgcacgtg ctggaacacg tgtggttccc ccctggccca gcctcctctg     1920

cagtgcccct ctcccctgcc catcctcccc acggaagcat gtgctggtca cactggttct     1980

ccaggggtct gtgatggggc ccctgggggt cagcttctgt ccctctgcct tctcacctct     2040

ttgttccttt cttttcatgt atccattcag ttgatgttta ttgagcaact acagatgtca     2100

gcactgtgtt aggtgctggg ggccctgcgt gggaagataa agttcctccc tcaaggactc     2160

cccatccagc tgggagacag acaactaact acactgcacc ctgcggtttg cagggggctc     2220

ctgcctggct ccctgctcca cacctcctct gtggctcaag gcttcctgga tacctcaccc     2280

ccatcccacc cataattctt acccagagca tggggttggg gcggaaacct ggagagaggg     2340

acatagcccc tcgccacggc tagagaatct ggtggtgtcc aaaatgtctg tccaggtgtg     2400

ggcaggtggg caggcaccaa ggccctctgg acctttcata gcagcagaaa aggcagagcc     2460

tggggcaggg cagggccagg aatgctttgg ggacaccgag gggactgccc cccaccccca     2520

ccatggtgct attctggggc tggggcagtc ttttcctggc ttgcctctgg ccagctcctg     2580

gcctctggta gagtgagact tcagacgttc tgatgccttc cggatgtcat ctctccctgc     2640

cccaggaatg gaagatgtga ggacttctaa tttaaatgtg ggactcggag ggattttgta     2700

aactgggggt atattttggg gaaaataaat gtctttgtaa aaagcttaaa aaaaaaaaaa     2760

aaaaa                                                                 2765


<210>  465
<211>  4089
<212>  DNA
<213>  homo sapiens

<400>  465
acggcccggc gacgggggag ttcccgcgag tggcctcgcg cccagaccgt gcggggggct       60

gttcgggtgg aggcggggga gccgccggga caccaaaata ggagctgctt gtggggtgga      120

gcggcactag ctggcggctt ccgagcgcct cttccaaaga tggtcagagg ggccggaggc      180

gtccccgctc ccgctcgcta ctagcccgcg ggccagcgcc gcgtcccgag ccccggcggg      240

agccatggct ctaaaaggac aagaagatta tatttatctt ttcaaggatt caacacatcc      300

agtggatttt ctggatgcat tcagaacatt ttacttggat ggattattta ctgatattac      360

tcttcagtgt ccttcaggca taattttcca ttgtcaccga gccgttttag ctgcttgcag      420

caattatttt aaggcaatgt tcacagctga catgaaagaa aaatttaaaa ataaaataaa      480

actctctggc atccaccatg atattctgga aggccttgta aattatgcat acacttccca      540

aattgaaata actaaaagaa atgttcaaag cctgcttgag gcagcggatc tgctacagtt      600

cctttcagta aagaaggctt gtgagcggtt tttggtaagg cacttggata ttgataattg      660

tattggaatg cactcctttg cagaatttca tgtgtgtcca gaactagaga aggaatctcg      720

aagaattcta tgttcaaagt ttaaggaagt gtggcaacaa gaagaatttc tggaaatcag      780

ccttgaaaag tttctcttta tcttgtccag aaagaatctc agtgtttgga aagaagaagc      840

tatcatagag ccagttatta agtggactgc tcatgatgta gaaaatcgaa ttgaatgcct      900

ctataatcta ctgagctata tcaacattga tatagatcca gtgtacttaa aaacagcctt      960

aggccttcaa agaagctgcc tgctcaccga aaataagatc cgctccctaa tatacaatgc     1020

cttgaatccc atgcataaag agatttccca gaggtccaca gccacaatgt atataattgg     1080

aggctattac tggcatcctt tatcagaggt tcacatatgg gatcctttga caaatgtttg     1140

gattcaggga gcagaaatac cagattatac cagggagagc tatggtgtta catgtttagg     1200

acccaacatt tatgtaactg ggggctacag gacggataac atagaagctc ttgacacagt     1260

gtggatctat aacagtgaaa gtgatgaatg gacagaaggt ttgccaatgc tcaatgccag     1320

gtattaccac tgtgcagtca ccttgggtgg ctgtgtctat gctttaggtg gttacagaaa     1380

aggggctcca gcagaagagg ctgagttcta tgatccttta aaagagaaat ggattcctat     1440

tgcaaacatg attaaaggtg tgggaaatgc tactgcctgt gtcttacatg atgttatcta     1500

cgtcattggt ggccactgtg gctacagagg aagctgcacc tatgacaaag ttcagagcta     1560

caattccgat atcaacgaat ggagcctcat cacctccagt ccacatccag aatatggatt     1620

gtgctcagtt ccgtttgaaa ataagctcta tctagtcggc ggacaaacta caatcacaga     1680

atgctatgac cctgaacaaa atgaatggag agagatagct cccatgatgg aaaggaggat     1740

ggagtgcggt gccgtcatca tgaatggatg tatttatgtc actggaggat actcctactc     1800

aaagggaacg tatcttcaga gcattgagaa atatgatcca gatcttaata agtgggaaat     1860

agtgggtaat cttcccagtg ccatgcggtc tcatgggtgt gtttgtgtgt ataatgtcta     1920

attgaatctg cagaaatgac caagcaatca cttttttgga gtatagtttt ataaaaaaag     1980

aatgcagggt ttgaagttcc ttacctgata attgtgtctg gcacatgata ggggatcagt     2040

aaattgtaat tcctaaccct actgtactcc caaacatggt gattcatggt caagaaaaat     2100

cttatatata tatatatata cacacacaca tatatgtgtt catatatatg tatacatata     2160

tatgtgtata tatacgtatg tatacatata tgtgtatata tacgtatgta tgtatacata     2220

tgtgtatata tagtatgtat gtatacatgt atgtgtatat atacgtatgt atgtatacat     2280

atatgtgtat acatatatat gtgtgtatat atatacacat atatacgtat atatgtgtat     2340

atatatacac agttgaatca gtgggattaa tacctataat ctctggtttt caaaggtaat     2400

atagaatatt tgacacttgg taaaaggtga actacctttg tagtgaatct tttcctcttg     2460

gtagcatcaa cactggggat aaatcagaac cattctgtgg aatgaaatgt ttctcaagag     2520

cctataatat agtagatagt gcatattaag atgtctggct gggcatggtg gctcatgcct     2580

gtaatcccag cactttggga ggctgaggcg ggaggatcac ttgagcctag aagttggaga     2640

ctaacctggc gagaccctgt ctcaaaaaaa aaaaaaaatc aatttagcta gcaggaattt     2700

gacatttaaa gagggaatct tctctacctc tacaaaatca acccttaaca cttttttcac     2760

cttcagaatt atttagaatg tggatttact ttgtctagtt ttttccttta tagtgtaatt     2820

tattgttact ctctatttac tgactaccag agatatacaa aatactgtgc aaaagattgt     2880

tactgttcaa agagcttaca aactaaattt aaaagaatag caagtctgaa aaatagaaga     2940

tagtcaaata tttgtttatg ctaagaactg tttttaattt tcagctttga tgtaaattgc     3000

tagcttagtt gtctttagtt caagcatgtt aggaaatcct ctttattctt aaatatagat     3060

acatgtctgc atatatgatt gaattttaga gccagaaagc atgtagagca gttgtgatta     3120

gtagaaaata cactgacaag aagatatttg catttatttc ccaaagctgc cagtaactag     3180

attttgtgac ttaagtcatt taacctctcc ttgattagag cttcctgagc catgcacact     3240

ggcactgcaa atcacagaca ggcctagata cagatcccct caccccttgc tacatccaaa     3300

ggtggcctgg gtggctggag cctctgggcc agaaccacct ttgtccattt tcctcagtgt     3360

gcctacagca tcgctttcca tgtgtgccat aacttgggaa tagttgggat gtgttgctta     3420

actcctttac accattagtt atctgtgaga ccatctattc cacactcttc attttttaaa     3480

aagagacaat aattattttt aactcactga agtttaaaac tacctagcat ttctgattaa     3540

aaaaaattta gaaggaaaat tttaatgcat ttatttcaga tggcgtttta aatagataca     3600

accctttgga aacacaatat ggtactacat agcaagggct gtaaaaatga ccatatcctt     3660

tgccccataa attctacttc tatactttta accttaaaaa taattcagaa aaaagataaa     3720

tgcatgaaga catttatgtc tgcattcttt ataataacaa aaattgggga aaaaaactcc     3780

atgtcaagaa agtgggataa gaaaaatagt gaagtattat actgccatta aaataattat     3840

ttggaagact gtagaaacgt ggacatgttt gatatggtaa gtaaaatgag cacaatacaa     3900

aatagtatgc atactatgat tgtgactttg taaaatcttt atgcatgtgg aaggtaatct     3960

gcaaaacaaa ttcattgtgt tagtgtagcg ggatatggaa tgactttatt tatttaaatc     4020

ttttctttaa tattactttg tattttcaat aaaaataaat cactgtacat agtaaaaaaa     4080

aaaaaaaaa                                                             4089


<210>  466
<211>  3598
<212>  DNA
<213>  homo sapiens

<400>  466
atctgtgatt ggctgaacgg accgacccgg aagggtggat gctctcagct ggctggcggg       60

aagattttac tcccgagtag cggaaagatc tgctcgaggc ctgggtgctt tggtgtcgga      120

gatccgagag tcggagatcg gagagtcgga cacaggacag tcggacaccg gacagtcaaa      180

caccggagag ttagaccggg cttctcggtg gggagaggct ctgggataac tactgttaca      240

gctttgaagg gtcaagggag gattggccac caaagcctgt ttattagcag ctgccatttg      300

ttgaaagaaa tttggattat tttagaaaca aatttggaaa gaaaaagaat ggcgtccgtt      360

tcagctctaa ctgaggaact ggattctata accagtgagc tacatgcagt agaaattcaa      420

attcaagaac ttacggaaag gcaacaagag cttattcaga aaaaaaaagt cctgacaaag      480

aaaataaagc agtgtttaga ggattctgat gccggggcaa gcaatgaata tgattcttca      540

cctgccgctt ggaataaaga agattttcca tggtctggta aagttaaaga tattctgcaa      600

aatgtcttta aactggaaaa gttcagacca cttcagcttg aaactattaa cgtaacaatg      660

gctggaaagg aggtatttct tgttatgcct acaggaggtg gaaagagctt atgttaccag      720

ttaccagcat tatgttcaga tggttttaca ctcgtcattt gcccattgat ctctcttatg      780

gaagaccaat taatggtttt aaaacaatta ggaatttcag caaccatgtt aaatgcttct      840

agttctaagg agcatgttaa atgggttcat gctgaaatgg taaataaaaa ctccgagtta      900

aagctgattt atgtgactcc agagaaaatt gcaaaaagca aaatgtttat gtcaagacta      960

gagaaagcct atgaagcaag gagatttact cgaattgctg tggatgaagt tcactgctgt     1020

agtcagtggg gacatgattt cagacctgat tataaggcac ttggtatctt aaagcggcag     1080

ttccctaacg catcactaat tgggctgact gcaactgcaa caaatcacgt tttgacggat     1140

gctcagaaaa ttttgtgcat tgaaaagtgt tttactttta cagcttcttt taataggcca     1200

aatctatatt atgaggttcg gcagaagccc tcaaacactg aagattttat tgaggatatt     1260

gtaaagctca ttaatgggag atacaaaggg caatcaggaa tcatatattg tttttctcag     1320

aaagactctg aacaagttac ggttagtttg cagaatctgg gaattcatgc aggtgcttac     1380

catgccaatt tggagccaga agataagacc acagttcata gaaaatggtc agccaatgaa     1440

attcaggtag tagtggcaac tgttgcattt ggtatgggaa ttgataagcc agatgtgagg     1500

tttgttatcc atcattcaat gagtaaatcc atggaaaatt attaccaaga gagtggacgt     1560

gcaggtcgag atgacatgaa agcagactgt attttgtact acggctttgg agatatattc     1620

agaataagtt caatggtggt gatggaaaat gtgggacagc agaagcttta tgagatggta     1680

tcatactgtc aaaacataag caaatgtcgt cgtgtgttga tggctcaaca ttttgatgaa     1740

gtatggaact cagaagcatg taacaaaatg tgcgataact gctgtaaaga cagtgcattt     1800

gaaagaaaga acataacaga gtactgcaga gatctaatca agatcctgaa gcaggcagag     1860

gaactgaatg aaaaactcac tccattgaaa ctgattgatt cttggatggg aaagggtgca     1920

gcaaaactga gagtagcagg tgttgtggct cccacacttc ctcgtgaaga tctggagaag     1980

attattgcac actttctaat acagcagtat cttaaagaag actacagttt tacagcttat     2040

gctaccattt cgtatttgaa aataggacct aaagctaatc ttctgaacaa tgaggcacat     2100

gctattacta tgcaagtgac aaagtccacg cagaactctt tcagggctga atcgtctcaa     2160

acttgtcatt ctgaacaagg tgataaaaag atggaggaaa aaaattcagg caacttccag     2220

aagaaggctg caaacatgct tcagcaatct ggttctaaga atacaggagc taagaaaaga     2280

aaaatcgatg atgcctgata tgaatgttac taaattttct aattaaagat ggtttatgca     2340

tgtatatgcc attatttttg tagttagaca atagttttta aaagaatttc atagatattt     2400

tatatgtatg gatctatatt ttcagagctt atctctgaag atctaaactt ttgagaatgt     2460

ttgaaaatta gagatcatga attatataat tttccagtat aaaacaaggg aaaaattttt     2520

atgtaaaacc ctttaaatgt aaaatatttg agaataagtt catacaatcg tcttaagttt     2580

tttatgcctt tatatactta gctatatttt ttcttttgac ataactatct ttttgaaagc     2640

aatattatac tgacagaggc tcactgagtg atactttaag ttaaatatgt agatcaagga     2700

tgtccaatct tttggcttcc ctgagccaca ttggaagaag aattgtcttg ggccgcacat     2760

aaaatatgct aacactgatg atagctgatg agcttaaaaa aaaaattgca agaaaaatct     2820

catgttttaa gaaagtttac aaaaaatgta aaatatttga gaataagttc atgtaattgt     2880

cttaagtttt ttatgccttt atatacttag ctatattttt tcttttgaca taaccatctt     2940

tttgaaagca atattatact gacagaggtt cactgagtga tactttaagt taaatatgta     3000

gatcagggat gtccaatctt ttggcttccc tgagccacat tggaagaaga attgtcttgg     3060

gccgcacata aaatatgcta acactgacga tagctgatga gcttaaaaaa aaaaaaattg     3120

caagaaaaat ctcatgtttt aagaaagttt acagatttgt gttgggctgc attcaaagct     3180

gttctgggct gcattagacc cgtgggctag agttggacaa gcttgtagat gatttcaggt     3240

tataaaacca gaagtacaat tcaacaaaaa aggagtaagt catcaatata aatattagca     3300

aacgagatat tgctacatct ctatttaaag taaaatacaa ccgattttaa agttcctgaa     3360

accatagcca tattttgaca tttcacaaag aatggttcta gtctactaga gtacatttgg     3420

ctaagtagat aacttaccta aatttgctcc aaagctaaat cacaagtaaa catatttatg     3480

tttaaaacac agaaataaat aacttaagat ttttatctaa gcggtcagtg ttgtattgga     3540

aagatatatc tataaataaa ctttgaactg atttcaaact taaaaaaaaa aaaaaaaa       3598


<210>  467
<211>  5507
<212>  DNA
<213>  homo sapiens

<400>  467
gcggccgcgg gctctcgcgg ggcggcgacg ccgcggggag gatgctgctt gccgcgcccg       60

cgtcctcacc gtcctcccgg gccgcctgct ggggctttgt tgtggcccgg acgccgcggg      120

ccaccccctg aagtcgcctg ccgccgccgc cgccgcacct agcggacggg cgggcgggcg      180

cgcgtgtgcc caggagtgcg cgcctgtcgc ggtggtgggt gcaggactgg acccacgggc      240

ccattgtgcg cccgcccgcg gcagccagga ccatgtgggt gaacccggag gaggtgttgc      300

tggccaacgc gctgtggatc accgagaggg ccaacccata cttcatcctg cagcggagga      360

agggccacgc cggcgatgga ggcggcggcg gcggactggc gggcctgctg gtgggtaccc      420

ttgatgttgt gttggactcc agcgcccggg tcgctcctta ccgaatcttg taccagactc      480

cagactccct ggtctactgg accatcgcct gtggtggttc caggaaagaa atcactgaac      540

actgggaatg gcttgagcaa aatctcttgc agacactctc catctttgaa aatgagaatg      600

atatcaccac atttgtgaga ggaaaaatac agggcatcat tgcagaatac aacaaaatca      660

atgatgtaaa ggaagatgat gacacggaga agtttaaaga agccattgtg aaatttcata      720

ggctgtttgg gatgccagag gaagagaaac tcgtcaacta ttactcttgc agctattgga      780

aggggaaggt cccccgtcag ggttggatgt acctcagcat taaccacctt tgcttttatt      840

cttttcttat gggaagggaa gcgaaactgg tcatccggtg ggtagacatc actcagcttg      900

agaagaatgc caccctgctt ctgcctgatg tgatcaaagt gagcacacgg tccagtgagc      960

atttcttctc tgtattcctc aacatcaacg agaccttcaa gttaatggag cagcttgcca     1020

acatagccat gaggcaactc ttagacaatg agggatttga acaagatcga tccctgccca     1080

aactcaaaag gaaatctcct aaaaaagtgt ctgctctaaa acgtgatctt gatgccaggg     1140

caaagagtga gagataccgt gcacttttcc ggctgcccaa agatgaaaaa ttagatggcc     1200

acacagactg cactctctgg actccattta acaaaatgca cattttgggg cagatgtttg     1260

tgtccacaaa ttacatctgt tttaccagca aggaggagaa cttatgtagc ctcattatcc     1320

cgctccgtga ggtgacaatt gtggaaaagg cagacagctc cagtgtgctc cccagtccct     1380

tatccatcag cacccgaaac aggatgacct tcctatttgc caacttgaaa gatagagact     1440

ttctagtgca gaggatctca gatttcctgc aacagactac ttccaaaata tattctgaca     1500

aggagtttgc aggaagttac aacagttcag atgatgaggt gtactctcga cccagcagcc     1560

tcgtctcctc cagcccccag agaagcacga gctctgatgc tgatggagag cgccagttta     1620

acctaaatgg caacagcgtc cccacagcca cacagaccct gatgaccatg tatcggcggc     1680

ggtctcccga ggagttcaac ccgaaattgg ccaaagagtt tctgaaagag caagcctgga     1740

agattcactt tgctgagtat gggcaaggga tctgcatgta ccgcacagag aaaacgcggg     1800

agctggtgtt gaagggcatc ccggagagca tgcgtgggga gctctggctg ctgctgtcag     1860

gtgccatcaa tgagaaggcc acacatcctg ggtactatga agacctagtg gagaagtcca     1920

tggggaagta taatctcgcc acggaggaga ttgagaggga tttacaccgc tcccttccag     1980

aacacccagc ttttcagaat gaaatgggca ttgctgcact aaggagagtc ttaacagctt     2040

atgcttttcg aaatcccaac atagggtatt gccaggccat gaatattgtc acttcagtgc     2100

tgctgcttta tgccaaagag gaggaagctt tctggctgct tgtggctttg tgtgagcgca     2160

tgctcccaga ttactacaac accagagttg tgggtgcact ggtggaccaa ggtgtctttg     2220

aggagctagc acgagactac gtcccacagc tgtacgactg catgcaagac ctgggcgtga     2280

tttccaccat ctccctgtct tggttcctca cactatttct cagtgtgatg ccttttgaga     2340

gtgcagttgt ggttgttgac tgtttcttct atgaaggaat taaagtgata ttccagttgg     2400

ccctagctgt gctggatgca aatgtggaca aactgttgaa ctgcaaggat gatggggagg     2460

ccatgaccgt tttgggaagg tatttagaca gtgtgaccaa taaagacagc acactgcctc     2520

ccattcctca cctccactcc ttgctcagcg atgatgtgga accttaccct gaggtagaca     2580

tctttagact catcagaact tcctacgaga aattcggaac tatccgggca gatttgattg     2640

aacagatgag attcaaacag agactgaaag tgatccagac gctggaggat actacgaaac     2700

gcaacgtggt acgaaccatt gtgacagaaa cttcctttac cattgatgag ctggaagaac     2760

tttatgctct tttcaaggca gaacatctca ccagctgcta ctggggcggg agcagcaacg     2820

cgctggaccg gcatgacccc agcctgccct acctggaaca gtatcgcatt gacttcgagc     2880

agttcaaggg aatgtttgct cttctctttc cttgggcatg tggaactcac tctgacgttc     2940

tggcctcccg cttgttccag ttattagatg aaaatggaga ctctttgatt aacttccggg     3000

agtttgtctc tgggctaagt gctgcatgcc atggggacct cacagagaag ctcaaactcc     3060

tgtacaaaat gcacgtcttg cctgagccat cctctgatca agatgaacca gattctgctt     3120

ttgaagcaac tcagtacttc tttgaagata ttaccccaga atgtacacat gttgttggat     3180

tggatagcag aagcaaacag ggtgcagatg atggctttgt tacggtgagc ctaaagccag     3240

acaaagggaa gagagcaaat tcccaagaaa atcgtaatta tttgagactg tggactccag     3300

aaaataaatc taagtcaaag aatgcaaagg atttacccaa attaaatcag gggcagttca     3360

ttgaactgtg taagacaatg tataacatgt tcagcgaaga ccccaatgag caggagctgt     3420

accacgccac ggcagcagtg accagcctcc tgctggagat tggggaggtc ggcaagttgt     3480

tcgtggccca gcctgcaaag gagggcggga gcggaggcag tgggccgtcc tgccaccagg     3540

gcatcccagg cgtgctcttc cccaagaaag ggccaggcca gccttacgtg gtggagtctg     3600

ttgagcccct gccggccagc ctggcccccg acagcgagga acactccctt ggaggacaaa     3660

tggaggacat caagctggag gactcctcgc cccgggacaa cggggcctgc tcctccatgc     3720

tgatctctga cgacgacacc aaggacgaca gctccatgtc ctcatactcg gtgctgagtg     3780

ccggctccca cgaggaggac aagctgcact gcgaggacat cggagaggac acggtcctgg     3840

tgcggagcgg ccagggcacg gcggcactgc cccggagcac cagcctggac cgggactggg     3900

ccatcacctt cgagcagttc ctggcctccc tcttaactga gcctgccctg gtcaagtact     3960

ttgacaagcc cgtgtgcatg atggccagga ttaccagtgc aaaaaacatc cggatgatgg     4020

gcaagcccct cacctcggcc agtgactatg aaatctcggc catgtccggc tgacacgggc     4080

gccttcccgg gggagtggga ggagagggag gggagggatt ttttatgttc ttctgtgttg     4140

agttttttct ttctttcttt taaattaaat atttattagt acctggcttg aagcctagtg     4200

ttttcataat gtaattcaat gaaaactgtt ggagaaatat ttaaacacct caatgtaggt     4260

acattacact cttgttgcgg ggaggggatt taccagaata cagtttattt cgtgaattct     4320

aaaaaacaaa aagatgaatc tgtcagtgat atgtgtgtat tataacttat taatcttgct     4380

gttgagctgt atacatggtt taaaaaatag tactgtttaa tgctaagtaa ggcagcagtc     4440

atttgtgtat tcaggctttt taaataaaat tagagctgta aggaaaatga aaagccacaa     4500

atgcaagact gttcttaaat ggaaggcata gtcagcgagg gtaaatccta taccacttta     4560

ggaagtatta aaaatatttt taagatttga aatatatttc atagaagtcc tctattcaaa     4620

atcatattcc acagatgttc cccttcaaag ggaaaacatt tggggttcta aacagttatg     4680

aaagtaagtg atttttacat gattccagaa taacacttgt attgaccaat ttagacagat     4740

accagaccaa ttttgcattt aagaaattgt tctgattatt tacgtcaact cattagaatt     4800

cagtgaaaag taacagtctt ttgtcacaga gaatctgaaa gtagcagcaa agacagaggg     4860

ctcatgacag gtttttgctt ttgctttgct tttgtttttg aaagagtaaa agtactgatg     4920

cttctgatac tggatgttta gcttcttact gcaaaaacat aagtaaaaca gtcaacttta     4980

ccatttccgt attctccata gattgaagaa atttatacca catatcgcat atgaccatct     5040

ttccatcaaa tcaatgtaga gataatgtaa actgaaaaaa aatctgcaag ataatgtaac     5100

tgaatgtttt aaaaacagaa cttgtcactt tatataaaag aatagtatgc tctatttcct     5160

gaatggatgt ggaaatgaaa gctagcgcac ctgcactttg aattcttgct tcttttttat     5220

tactgttatg attttgcttt ttacagatgt tggacgattt tttcttctga ttgttgaatt     5280

cataatcatg gtctcatttc ctttgcttct ttggaatatt tctttcaaca cattccttta     5340

ttttattata cattgtgtcc tttttttagc tattgctgct gttgtttttt attctattta     5400

caggatgatt tttaaactgt caaatgaagt agtgttaacc tcaaataggc taaatgtgaa     5460

caaataaaat acagcaaata ctcagaaaaa aaaaaaaaaa aaaaaaa                   5507


<210>  468
<211>  2856
<212>  DNA
<213>  homo sapiens

<400>  468
gcccgccgcc cggcgacgcg cccgccggcg tccccggagg tgcccccggc ccggccgggt       60

cgtcgccccg ccgccgcgcc cgcgagccgc tttgtctcgg gcggggcgcg cgggagaggc      120

cgccaggtgc cccccgccac gggcccgggc cccccgcccc ggggcggcgg cggcggcgcc      180

gggccccggg gcggggggcg cgccgggatg ggccccaaga ggcgacagct gacgttccgg      240

gagaagtcac ggatcatcca ggaggtggag gagaatccgg acctgcgcaa gggcgagatc      300

gcgcggcgct tcaacatccc gccgtccacg ctgagcacga tcctgaagaa caagcgcgcc      360

atcctggcgt cggagcgcaa gtacggggtg gcctccacct gccgcaagac caacaagctg      420

tctccctacg acaagctcga gggcttgctc atcgcctggt tccagcagat ccgcgccgcc      480

ggcctgccgg tcaagggcat catcctcaag gagaaggcgc tgcgcatagc cgaggagctg      540

ggcatggacg acttcaccgc ctccaacggc tggctggacc gcttccgccg gcgccacggc      600

gtggtgtcct gcagcggcgt ggcccgcgcc cgcgcgcgaa acgctgcccc ccgcaccccg      660

gcggcgcctg ccagtccggc cgcggtgccc tcggagggca gtggcgggag cactactggt      720

tggcgcgctc gggaggagca gccgccgtcg gtggccgagg gctacgcctc gcaggacgtg      780

ttcagcgcca ccgagaccag tctatggtac gacttcctgc ccgaccaggc cgcggggctg      840

tgcggaggcg acggacggcc gcgtcaagcc acccagcgcc tgagcgtcct gctatgcgcc      900

aatgccgacg gcagcgagaa gctgcccccg ctggtggccg gcaagtcggc caagccccgc      960

gcaggccaag ccggcctgcc ctgcgactac accgccaact ccaagggtgg tgtcaccacc     1020

caggccctgg ccaagtactt gaaggccttg gacacccgaa tggctgcaga gtctcgccgg     1080

gtcctgctgt tggccggccg cttggctgcc cagtccttgg acacctcggg cctgcggcat     1140

gtgcagctgg ccttcttccc tcccggcacc gtgcatccgc tggagagggg agtggtccag     1200

caggtgaagg gccactaccg ccaggccatg ctgctcaagg ccatggccgc gctagagggc     1260

caggatccct caggcctgca gctgggtctc acggaggccc tgcactttgt ggctgccgcc     1320

tggcaggcag tggagccttc ggacatagcc gcctgctttc gtgaggctgg ctttgggggt     1380

ggccctaatg ccaccatcac cacttccctc aagagtgagg gagaggaaga ggaggaggag     1440

gaggaagaag aggaggagga agagggtgaa ggagaggaag aggaggagga aggggaggag     1500

gaggaggagg aaggggggga aggagaggaa ttgggggagg aagaggaggt ggaggaggag     1560

ggtgatgttg atagtgatga agaagaggag gaagatgagg agagctcctc ggagggcttg     1620

gaggctgagg actgggccca gggagtagtg gaggccggtg gcagcttcgg ggcttatggt     1680

gcccaggagg aagcccagtg ccctactctg catttcctgg aaggtgggga ggactctgat     1740

tcagacagtg aggaagagga cgatgaggaa gaggatgatg aagatgaaga cgacgatgat     1800

gatgaggagg atggtgatga ggtgcctgta cccagctttg gggaggccat ggcttacttt     1860

gccatggtca agaggtacct gacctccttc cccattgatg accgcgtgca gagccacatc     1920

ctccacttgg aacacgatct ggttcatgtg accaggaaga accacgccag gcaggcggga     1980

gttcgaggtc ttggacatca aagctgagtc actggaccta gctgtgcccc caacctagat     2040

tggcagcacc accccagggc agaggactct ctgggcaccc gctgtgcatg gagccagagt     2100

gcagagcccc agatccttta gtaatgcttc ccctggtcct gcaacaggcc cggtcacctc     2160

ggccgggccc ggggctgagg tcagcctcac tgcctgctta ttgcctcttt ctcagaatcc     2220

tctttcctcc ccatttggcc ctgggctcag gggaccaggt ggggcgggtg gggagctgtc     2280

cggtgctacc acaccgtgcc ctcagtggac taaccacagc agcagccagg gatgggccct     2340

ggaggttccc ggccggagag tgcctctccc ctctgccatc cacgtcaggt ctttggtggg     2400

gggaccccaa agccattctg ggaagggctc cagaagaagg tccagcctag gccccctgca     2460

aggctggcag cccccacccc caccccccag gccgccttga gaagcacagt ttaactcact     2520

gcgggctcct gagcctgctt ctgcctgctt tccacctccc cagtcccttt ctctggccct     2580

gtccatgtga ctttggccct tggttttctt tccagattgg aggtttccaa gaggcccccc     2640

accgtggaag taaccaaggg cgcttccttg tgggcagctg caggccccat gcctctcctc     2700

cctctctggc agggccccat cctgggcaga ggggcctggg gctgggccca gagtccagcc     2760

gtccagctgc tcctttccca gtttgatttc aataaatctg tccactcccc ttttgtgggg     2820

gtgaacgttt taacagccaa aaaaaaaaaa aaaaaa                               2856


<210>  469
<211>  2095
<212>  DNA
<213>  homo sapiens

<400>  469
cttttaaagt ttgaggggcg gtggtggcgg cggccggcag gcgcggggga acacaggggc       60

cgctacggga gccgcgccgc cgcccatgtc attccacttc aagtgacttc atgtgatgtc      120

agctgaatgt aaaagacagt gatctcacgc ggaggggaag atgtttgcca tcaaaatgtg      180

acagaagaga cacgctgcat ggctcggaac gcatctcctt ggtggtgggg gaaagagact      240

tagaggagag aggctgcgcc ctggcccagc ctggctcggc tcagctccgc gcgccatggc      300

aagctcggct tccctggaga ccatggtgcc cccggcctgc ccgcgcgccg gagcgtcgcc      360

ggccacttcc aagacactgg ccttttccat cgagcgcatc atggccaaga cgtcggagcc      420

ccgtgcgccc tttgagcccc ggcctggagc gctagaggcg gacggcagcc agggcaagaa      480

actgctcaac ctctgctcgc cgctgccctg tatgatcccc ctccagcccc taggctacga      540

ggtgccgtca aagacactgc tcagttactc ggagctctgg aaaagcagcc tccgggcggg      600

cggcggcgga ggcggcggcg gcggtggcgg cggcggcggc gggggggccc cagtgtgcgg      660

cgccagcggc ttgtgcaaaa ccaactgtgg cgtgtgctgc aaggccgagc tgggcctggc      720

gccgtccgcg ctgcccgcgg gcagggtcat caagccgcag gtcatcaacc aggctgtggg      780

gctgccggcc agcggctcgc tctactactt caactacctg gactcgaccg cgtacccgcc      840

gtctgagctc ctcagcggcc acctcttccc gtctggcctc ctcaatgcgc aggcccccgc      900

cgccctggct gctcacccca agctctttct gctggagaac gccaagctgg ccggcctggc      960

tgcggacaag ttcccccacc cggctcccta tccccataag gagcgcttgc cggcgccgct     1020

ggagcaggta ctgaaggaaa actcggccct gactgccgag cgcggaggcg tcaagggcca     1080

cagcaagctg ccaggaggct ccgcagatgg caagcccaaa aacttcacct gcgaggtgtg     1140

cggcaaggtg tttaacgctc actataatct cacccgccac atgccggtcc acaccggagc     1200

cagaccgttc gtgtgcaaag tctgcggcaa aggctttcgc caggccagca cgctctgcag     1260

gcacaaaatt atccacaccc aggaaaagcc acataaatgc aaccagtgcg gcaaagcgtt     1320

caaccgcagc tccacgctca acacgcatat ccgcatccac gcgggctaca agcccttcgt     1380

ctgcgaattt tgcggcaaag gctttcacca aaaagggaac tacaagaacc acaagctgac     1440

ccacagcggc gagaagcagt acaaatgtac catctgcaac aaggccttcc accaggtcta     1500

caacctaacc ttccatatgc acacccacaa cgacaagaag cctttcacgt gcgccacttg     1560

cggcaaaggg ttttgcagaa actttgactt aaagaaacat gtgcgcaaac tccacgacag     1620

cgtgggccct gctgccccct ccgcaaagga cctgactagg acagtgcaga gctgagagct     1680

actgccttgc ccttccttcc ctccctgtac cacctgaaaa cagatcacac atataaactt     1740

atttctaaaa ttaaaagaaa aaaaaactat agcagagagg ctaaaatcta tttatcgaaa     1800

ccagcatatt tttggaaagc taaatgtttc ctcgatgact ggcagcaaac tcgtggcccc     1860

cacctttgta tattcaggaa acttatttaa atccagtgcg ccgaaacgta tttaattcca     1920

ggcctccgct tctcctgggg cagccagttt taaccccagc ctgtcaccgt gagcgcccca     1980

gaagagcgcg gcgcccctag ccatctttat acagccatgt aaatcctcct gtacaagcga     2040

acacggaata tatacatata taactcaata aacagaatca ttagtgaaaa aaaaa          2095


<210>  470
<211>  4077
<212>  DNA
<213>  homo sapiens

<400>  470
agcttctgta agagacggag aggcgcagag tgagggcggg tccgcgcgtc ctcagagccc       60

gctggaggct cggagctgct acccgcagac ttctcccgca cagggctcgc aaagagcgtg      120

attccgagag cctgagactg acgcccgacc tggaaaccag agaagacttc cttagccttt      180

cggatcgcac ttgaggctgg aggcatgagt cctgtgaggc gttggggcag cccctgcctt      240

ttccccttgc agctcttcag cctctgctgg gtgctctcag tggcccagag caaaacagtc      300

cgatacagca ccttcgagga ggatgccccc ggcacggtca tcgggaccct ggccgaggac      360

ctgcatatga aagtatcggg tgacacaagc ttccgcctga tgaagcaatt caacagctct      420

ctgctccggg tgcgcgaagg cgacgggcag ctgaccgtcg gggacgccgg cctggaccgc      480

gagcggctgt gtggccaggc cccgcagtgc gtgctggcct tcgatgtggt cagcttctcg      540

caggagcagt tccggctggt gcacgtggag gtagaggtga gggacgtcaa cgaccacgcg      600

ccgcgcttcc ccagggccca gatcccggta gaggtgtccg agggtgcggc agtgggcacg      660

cgcatcccct tggaggtgcc ggtggacgag gacgtgggcg ccaacgggct gcagaccgtg      720

cgcctggccg agccgcacag cccctttcgc gtggagctgc agacgcgagc ggacggcgct      780

cagtgcgcag acctggtgct gctgcaggag ctggaccgcg agagccaggc cgcctacagc      840

ctggagctgg tggcccagga cggcggccgc ccgccgcgct ccgccacggc tgccctcagc      900

gtgcgcgtcc tggatgcgaa tgaccacagc ccggccttcc cgcagggcgc cgtggccgaa      960

gtggagctgg cggaagacgc gcccgtgggc tccctgcttc tcgacctgga cgcagccgac     1020

cccgacgagg gacctaacgg cgacgtggtg ttcgcatttg gcgcccgcac cccgccggag     1080

gcgcgccgcc tctttcggct tgacccgcga tcaggccgcc tcaccctggc cgggcccgtg     1140

gactacgagc gtcaggacac ctacgagctg gacgtgcggg cgcaggaccg cggacccggg     1200

ccccgcgctg ccacctgcaa ggtcatcgtg cgcatccgag acgtcaatga caacgcaccc     1260

gacatcgcca tcaccccgct ggccgcccca ggcgcgccgg caacctcacc cttcgccgct     1320

gccgccgccg ccgctgcact cgggggagcg gacgctagct cgccggcggg agccgggacg     1380

ccggaggctg gtgccacttc gctggtgccg gagggggcgg cgcgcgagag cctggtggcc     1440

ctggtcagca cctcggacag ggactcgggc gccaacgggc aagtgcgctg cgccctctat     1500

gggcacgagc acttccggct gcagccggcc tacgcgggca gctacctggt ggtgaccgcg     1560

gcgtcgctgg accgcgaacg catcgccgag tacaacttga cgctggtggc cgaggatcgc     1620

ggcgcgcccc cgctgcgcac agtgcggccc tacacggtgc gtgtgggcga cgagaacgac     1680

aacgcgccgc tcttcacgcg gccggtctat gaggtgtcgg tgcgcgagaa caacccgcca     1740

ggcgcctacc tggccacggt ggccgcccgc gaccgggacc tgggccgcaa cggccaggtc     1800

acctaccggc tgctggaggc cgaggtgggc cgcgccgggg gcgccgtgtc cacttatgtc     1860

tcggtggacc cagctaccgg agccatctac gcgctgcgca gcttcgacta tgagacgctg     1920

cgccaactcg acgttcgcat ccaagctagc gacggcggct cccctcagct ttccagcagc     1980

gccctagtgc aagtgcgcgt gctggaccag aacgaccatg cgccagtcct ggtgcacccg     2040

gcgccagcca atggctccct agaagtggcg gtgcctgggc gcaccgcaaa ggacacggtt     2100

gtggcccgtg tgcaggcccg ggatgcagac gagggagcca acggggagct ggcgttcgag     2160

ctgcagcagc aggagccgcg cgaagccttc gccatcggcc gccgcacggg ggagatactg     2220

ctcaccggcg acctctcgca ggagccaccc ggtcgcgtgt tcagggcgct cctggtcata     2280

tccgacggcg gccgtccccc gctcaccacc accgcaactg tcagcttcgt ggtaacagca     2340

gggggcgggc gtgggccggc tgcgcctgcc agtgcaggaa gcccggagcg ttcccgcccg     2400

cctggctctc ggctcggggt gtccgggtcg gtgctgcaat gggacacgcc gctgatcgtc     2460

atcatcgtgc tggccgggag ctgcacgctg ctgctggccg ccatcatcgc catcgccacc     2520

acctgcaacc gccgcaagaa ggaggtgcgc aaaggggggg ccctccggga agagcggccc     2580

ggggcggcgg gcggcggagc ctcggctccc ggctccccgg aggaggccgc ccggggagcc     2640

gggcccaggc ccaacatgtt cgacgtgctc accttccctg gcaccggcaa agcgcccttt     2700

ggcagccccg cggcggacgc gcctccgcct gcggtcgccg cggccgaagt gccgggctca     2760

gagggcggca gcgccactgg ggaaagcgcc tgtcacttcg aggggcagca gcggctccgc     2820

ggcgcgcacg ccgagcccta cggtgcctcc ccgggttttg gaaaggagcc ggcgccccct     2880

gtggcggtgt ggaaaggaca ctccttcaac accatttctg gcagagaagc agagaagttc     2940

agcggcaaag acagcggtaa aggggacagt gatttcaacg acagcgattc cgacatcagc     3000

ggggacgctc tgaaaaagga tctcatcaac cacatgcaga gtggactgtg ggcgtgcacc     3060

gctgagtgta agatcctggg ccactctgac cgctgctgga gcccatcctg cagcgggccc     3120

aacgcacatc catcgcctca cccaccagcc cagatgtcaa ccttctgtaa gagcacgtca     3180

ctgcctcggg atcctctgcg cagggacaat tactaccagg cccagctgcc caagacagtg     3240

gggctgcaga gcgtctatga gaaagtactg cacagagact atgacaggac agtcactctg     3300

ctctcccctc cccgtccagg gaggctccca gacctgcagg agattggagt acccctctac     3360

cagtcccctc ctggcaggta cctgtccccg aagaagggag ccaatgaaaa tgtgtaatcc     3420

catgctgcat gtcttcacac atatacaggt cactccgaga agcccctaag ttattgaccg     3480

gtttcagtgt tgtatatata aatatgcaag atgtgcctta caatgaagtt gttggaagct     3540

atttccaatc acattggtac tgtttggtat ttgcaaacaa aaatgtagtt aatgtaattt     3600

ttatgaaatg tgtgcagtat ttaatttttc ttatgctatt gactttgatt tcaattgcgg     3660

cttgccattt tcttagtgtt tttaacctgt acattgtgta atgtaatgtt tgtatataat     3720

gaaattttgt tatattttta tataataaaa gctaaagtgg aagttattgc caaaggaact     3780

gtctgtaaga caaaaaacaa aacatgttgg aattacttaa ttgaaattta tctttcacct     3840

gaaacaacct agtgtttgag aaattttgcc ttgccaagta taacttgtat atcttgactc     3900

tgtggtagat ttcaagttca atgttattta attacatttg gttttccgta aaccgtgtca     3960

cttataagca cagtaataaa agatttgtca tgtgtttgaa gaaaaaaaaa aaaaaaaaaa     4020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa        4077


<210>  471
<211>  3965
<212>  DNA
<213>  homo sapiens

<400>  471
atctgacgag cggccattca tcaggccggc tggcctatca atgacattgc tcccatcggg       60

gctcctataa aatgatgctt tttcccatga aacatccgca aacattttga cgggtttggc      120

tttgcccggc tggattactg agtgtcccct tgctcgctcg ctttttctct ctcccccttc      180

tccgagctcg ctcccttctc tccctctctc tcctcttttc ttctttctct tttctttcct      240

cttctttttc ttttcttttc ctttcctcct ttatccttgt gccccctcac tttctgcgtc      300

tctctctctc cccttctccc tccctccctc ccttcctccc tgggcatctc tagcacaggg      360

gatccccaaa catcaggact tttggggggc gcctgtgctg tccatgggaa gagcatgcat      420

tgtgggttac tggaggaacc cgacatggat tccacagaga gctggattga aagatgtctc      480

aacgaaagtg aaaacaaacg ttattccagc cacacatctc tggggaatgt ttctaatgat      540

gaaaatgagg aaaaagaaaa taatagagca tccaagcccc actccactcc tgctactctg      600

caatggctgg aggagaacta tgagattgca gagggggtct gcatccctcg cagtgccctc      660

tatatgcatt acctggattt ctgcgagaag aatgataccc aacctgtcaa tgctgccagc      720

tttggaaaga tcataaggca gcagtttcct cagttaacca ccagaagact cgggacccga      780

ggacagtcaa agtaccatta ctatggcatt gcagtgaaag aaagctccca atattatgat      840

gtgatgtatt ccaagaaagg agctgcctgg gtgagtgaga cgggcaagaa agaagtgagc      900

aaacagacag tggcatattc accccggtcc aaactcggaa cactgctgcc agaatttccc      960

aatgtcaaag atctaaatct gccagccagc ctgcctgagg agaaggtttc tacctttatt     1020

atgatgtaca gaacacactg tcagagaata ctggacactg taataagagc caactttgat     1080

gaggttcaaa gtttccttct gcacttttgg caaggaatgc cgccccacat gctgcctgtg     1140

ctgggctcct ccacggtggt gaacattgtc ggcgtgtgtg actccatcct ctacaaagct     1200

atctccgggg tgctgatgcc cactgtgctg caggcattac ctgacagctt aactcaggtg     1260

attcgaaagt ttgccaagca actggatgag tggctaaaag tggctctcca cgacctccca     1320

gaaaacttgc gaaacatcaa gttcgaattg tcgagaaggt tctcccaaat tctgagacgg     1380

caaacatcac taaatcatct ctgccaggca tctcgaacag tgatccacag tgcagacatc     1440

acgttccaaa tgctggaaga ctggaggaac gtggacctga acagcatcac caagcaaacc     1500

ctttacacca tggaagactc tcgcgatgag caccggaaac tcatcaccca attatatcag     1560

gagtttgacc atctcttgga ggagcagtct cccatcgagt cctacattga gtggctggat     1620

accatggttg accgctgtgt tgtgaaggtg gctgccaaga gacaagggtc cttgaagaaa     1680

gtggcccagc agttcctctt gatgtggtcc tgtttcggca caagggtgat ccgggacatg     1740

accttgcaca gcgcccccag cttcgggtct tttcacctaa ttcacttaat gtttgatgac     1800

tacgtgctct acctgttaga atctctgcac tgtcaggagc gggccaatga gctcatgcga     1860

gccatgaagg gagaaggaag cactgcagaa gtccgagaag agatcatctt gacagaggct     1920

gccgcaccaa ccccttcacc agtgccatcg ttttctccag caaaatctgc cacatctgtg     1980

gaagtgccac ctccctcttc ccctgttagc aatccttccc ctgagtacac tggcctcagc     2040

actacaggag caatgcagtc ttacacgtgg tctctaacat acacagtgac gacggctgct     2100

gggtccccag ctgagaactc ccaacagctg ccctgtatga ggaacactca tgtgccttct     2160

tcctccgtca cacacaggat accagtttat ccccacagag aggaacatgg atacacggga     2220

agctataact atgggagcta tggcaaccag catcctcacc ccatgcagag ccagtatccg     2280

gccctccctc atgacacagc tatctctggg ccactccact atgcccctta ccacaggagc     2340

tctgcacagt acccttttaa tagccccact tcccggatgg aaccttgttt gatgagcagt     2400

actcccagac tgcatcctac cccagtcact ccccgctggc cagaggtgcc ctcagccaac     2460

acgtgctaca caagcccgtc tgtgcattct gcgaggtacg gaaactctag tgacatgtat     2520

acacctctga caacgcgcag gaattctgaa tatgagcaca tgcaacactt tcctggcttt     2580

gcttacatca acggagaggc ctctacagga tgggctaaat gactgctatc ataggcatcc     2640

atatttaata ttaataataa taattaataa taataataaa cccaacaccc atcccccaga     2700

agactttatc tctatacatt gtaactcatg ggctattcct aagtgcccat tttcctaatg     2760

aacatgagga tgggatcaat gtgggatgaa taaactttag ttcagaaaca ggacttacta     2820

aaagtcagtg ggactgggtt tctgtagcca agccagactt gactgtttct gtagagcact     2880

atctcgggca ggccattctg tgccttttcc ctctgttcca tgactttgct ttgtgttggc     2940

aaccacttct agtaagctac tgattttcct gttgacaaaa tctctttagt cttgaaggat     3000

ggatactgga gacagaatct ggtttgtgtt cttggatggg cacataattt accaagagca     3060

ttcaccttgc catctgtctt gtcattgtac tgtacaagga acagccctca gacgtgttct     3120

gcacatccct tcttcctggt ggtaccatcc ctatttcctg gagcaccagg gctaaatggg     3180

gagctatctg gaaactctag attttctgtc atacccacat ctgtcacagt acctgcattg     3240

tcttggaatg taagcactgt cttgagggaa ggaagaggtc tgttctgtat tgccttaagt     3300

tgattgaggt ttgtaggaga ctggttcttc tacatacaag gatttgtctt aagtttgcac     3360

aatggctagt gtcagcaaaa ggcaggagag ggtttttgtt ttttttttaa gttctatgag     3420

aatgtggatt tatggcattg agtatcacac tcagctctgc tgtgttaact ttgtgaaact     3480

ggatggaaca aactttaact taccaagcac caagtgtgaa agtgactttc acggttcctt     3540

cataaaacta taataatatc cgacactttg atagaaaaaa attcaaagct gtgcctttga     3600

gcctatacta tactgtgtat gtgtggaaat aaaaatgtat tgtacttttg gagaattttt     3660

tgtaggcatt tttctgtcag atttgtagta atttgtgagg tttgttagag attaatatag     3720

gttttctttc tgtattataa aatgcaccaa gcaattatgg tggacctatt accctatggg     3780

taagaaataa atggaaatat gacatcggat gtttcagcaa ctgttctgta aataaaatct     3840

ttgatcacac cactcagtgt gataattgtg tctacagcta aaatggaaat agttttatct     3900

gtacagttgt gcaagatatg aatggtttca cactcaaata aaaaatattg aaacgacaaa     3960

aaaaa                                                                 3965


<210>  472
<211>  2112
<212>  DNA
<213>  homo sapiens

<400>  472
aaaacgggct cagttcgtaa aggagccggg tgacttcaga ggcgccggcc cgtccgtctg       60

ccgcacctga gcacggcccc tgcccgagcc tggcccgccg cgatgctgta gggaccgccg      120

tgtcctcccg ccggaccgtt atccgcgccg ggcgcccgcc agacccgctg gcaagatgcc      180

gcgctccttc ctggtcaaga agcatttcaa cgcctccaaa aagccaaact acagcgaact      240

ggacacacat acagtgatta tttccccgta tctctatgag agttactcca tgcctgtcat      300

accacaacca gagatcctca gctcaggagc atacagcccc atcactgtgt ggactaccgc      360

tgctccattc cacgcccagc tacccaatgg cctctctcct ctttccggat actcctcatc      420

tttggggcga gtgagtcccc ctcctccatc tgacacctcc tccaaggacc acagtggctc      480

agaaagcccc attagtgatg aagaggaaag actacagtcc aagctttcag acccccatgc      540

cattgaagct gaaaagtttc agtgcaattt atgcaataag acctattcaa ctttttctgg      600

gctggccaaa cataagcagc tgcactgcga tgcccagtct agaaaatctt tcagctgtaa      660

atactgtgac aaggaatatg tgagcctggg cgccctgaag atgcatattc ggacccacac      720

attaccttgt gtttgcaaga tctgcggcaa ggcgttttcc agaccctggt tgcttcaagg      780

acacattaga actcacacgg gggagaagcc tttttcttgc cctcactgca acagagcatt      840

tgcagacagg tcaaatctga gggctcatct gcagacccat tctgatgtaa agaaatacca      900

gtgcaaaaac tgctccaaaa ccttctccag aatgtctctc ctgcacaaac atgaggaatc      960

tggctgctgt gtagcacact gagtgacgca atcaatgttt actcgaacag aatgcatttc     1020

ttcactccga agccaaatga caaataaagt ccaaaggcat tttctcctgt gctgaccaac     1080

caaataatat gtatagacac acacacatat gcacacacac acacacacac ccacagagag     1140

agagctgcaa gagcatggaa ttcatgtgtt taaagataat cctttccatg tgaagtttaa     1200

aattactata tatttgctga tggctagatt gagagaataa aagacagtaa cctttctctt     1260

caaagataaa atgaaaagca cattgcatct tttcttccta aaaaaatgca aagatttaca     1320

ttgctgccaa atcatttcaa ctgaaaagaa cagtattgct ttgtaataga gtctgtaata     1380

ggatttccca taggaagaga tctgccagac gcgaactcag gtgccttaaa aagtattcca     1440

agtttactcc attacatgtc ggttgtctgg ttgccattgt tgaactaaag cctttttttg     1500

attacctgta gtgctttaaa gtatattttt aaaagggagg aaaaaaataa caagaacaaa     1560

acacaggaga atgtattaaa agtatttttg ttttgttttg tttttgccaa ttaacagtat     1620

gtgccttggg ggaggaggga aagattagct ttgaacattc ctggcgcatg ctccattgtc     1680

ttactatttt aaaacatttt aataattttt gaaaattaat taaagatggg aataagtgca     1740

aaagaggatt cttacaaatt cattaatgta cttaaactat ttcaaatgca taccacaaat     1800

gcaataatac aatacccctt ccaagtgcct ttttaaattg tatagttgat gagtcaatgt     1860

aaatttgtgt ttatttttat atgattgaat gagttctgta tgaaactgag atgttgtcta     1920

tagctatgtc tataaacaac ctgaagactt gtgaaatcaa tgtttctttt ttaaaaaaca     1980

attttcaagt tttttttaca ataaacagtt ttgatttaaa atctcgtttg tatactattt     2040

tcagagactt tacttgcttc atgattagta ccaaaccact gtacaaagaa ttgtttgtta     2100

acaagaaaaa aa                                                         2112


<210>  473
<211>  4278
<212>  DNA
<213>  homo sapiens

<400>  473
agagggaaaa taattcttca aaaaagaaaa gtcagtcttc tcctctccag tccgtggaaa       60

atccaacggg gacgttgaca agagggtatt tttaggaaac acatccaaat atacagggta      120

agagtgaatg tgagaaaaaa aaaagttgtg ggttgtagaa gttatcaagt gggatttgcg      180

gcgctctctg caggaaacgc gaacggctcc agttcaaagc cacatgcacc aacgtgacat      240

ataagccatt aaaatatcat cctgacggct catttctgct tcatcataca ttccctaact      300

gcttcctgaa agctggaaaa ggagaagtga aggatgaccg cctcgctgga accacaaaag      360

agaggcttgg aggggtttgt ggtcccctct cagccacccc gaaatgatgt gcagaaatga      420

ggcgatcctg gcaacaggtg gagtggggct caaagtcaga aaatgagata caagacatcc      480

ttggtgatga ggaaacgatt acggctttac cgaaacactc ttaaagagtc aagtagcagc      540

tctggacacc atggccccca gctcaccgcc gcctccagcc cctcggtgtt cccgggcctc      600

cacgaggagc ctccccaggc ctcccccagc cgtcctttga atggactcct gcgtctgggg      660

ctccctggag acatgtacgc gcggccggag cccttcccgc cagggcctgc ggcccgcagc      720

gacgccctgg cagctgccgc agccctgcat ggctacgggg gcatgaacct gacggtgaac      780

ctcgctgcgc cccacggtcc tggcgctttc ttccgctaca tgcgccagcc catcaaacag      840

gagctcatct gcaagtggct ggcggccgac ggcaccgcga ccccgagcct ctgctccaaa      900

actttcagca ccatgcacga gctggtcacg cacgtcaccg tggagcacgt cggcggcccg      960

gaacaggcca accacatttg cttctgggag gagtgtccgc gccagggaaa gcccttcaaa     1020

gccaaataca aacttgtaaa tcacatccgc gtgcacacgg gcgagaagcc cttcccttgt     1080

cctttcccgg ggtgtgggaa ggtctttgct agatcagaaa atctcaaaat acacaaacga     1140

actcacacag gcgagaagcc cttcagatgc gagttcgagg gctgcgagcg gcgcttcgcc     1200

aacagcagcg accgtaagaa gcattcgcac gtgcacacta gcgacaagcc atacacgtgc     1260

aaggtgcggg gctgcgacaa gtgctacacg caccccagct cgctgcgtaa gcacatgaag     1320

gtgcacgggc gctcgccgcc gcccagctct ggctacgatt cggctacacc gtctgccctc     1380

gtgtcgccct cgtcggactg cggccacaag tcccaggtgg cctcctcggc ggcggtggcg     1440

gcgcgtaccg ccgacttgag cgaatgatgt ccaccgcgtt gctcgcaagg taatctcgct     1500

ccgcgcagct gagcgccccg catctcgcgc ctgctacatc aaagggcccg cgcacaaagc     1560

agtgtttctt cgccacggtg catcttcatg gtaagttagg atttctatgg caatgtgcaa     1620

gtcgcactga aatcctgaaa ggccaagcct ggagcccgtc caggcttttc attaaggaca     1680

taatatttac gtctaacaga ccttttttct tgtgtataca agtatatatt tttgtttgac     1740

gcggactaaa tcattttcat ttaatttccg gtaaacaaaa cccacgcgaa tgggcacttg     1800

tacccgatca taataaaaat ggataataat gtgaaggaag aaaagagccg cttgaatcgc     1860

cgctcagccc cctttgtttc tgctttctgc ggtgatcaga gggcgcgttt gggtttgatg     1920

gcgagtttct aaaggcgagg aaatggtttg taagagggga aagaaaagga gaaaggtcta     1980

atcaagctcg ggttgttcaa agagtcgggt tttggggttg aaagtgtgag tttgacggtg     2040

catcagcatg ccgcgttagg ctcgccatgg aaatacgcgc ggggagcggc cgcttcaaag     2100

gcggcacact tcactacaga cactctatta agatacattt gcgctgacct ttgctttcac     2160

gccatttaat actgtcactg cgctctccag tatatacttc ctttctagaa cccgacttgc     2220

ccacgtttag gggttcactc tgcaccctga tgtgggaggc tttggcgcag gggacacttt     2280

caggaaaggg aggagcacaa ggactctgtg catcttgact gcaccccaaa gaggctccag     2340

gatcaggagt gaaagatttt aaagcagcct ccgaagctta acaaatgagc attccaagct     2400

cagttttgtg caaatcgcct ttctgactct tgagtaggat ggaggcttaa atttaatggc     2460

gacttggggg gaagggagcc accctggggg agtctgagga gttcagactg tgcccttggg     2520

aatttccact ctggctttcc gtgccactct tcttcctttc catcccaaaa gtctcttgcg     2580

gcccctgaaa cttgtttctt tctaaggcag ggtgtgtggt acccttaggc ctggactagt     2640

cctagatgca aactcaagag cccaaggcca aggggatgtg gggaagatgg caggaaagtt     2700

agaagtccat gttcccttaa ttgtcttgtt gtttatttta tccaagtacc ccagtgaata     2760

ggggaaaaat aaacacagtg aaaaaaaaaa tcaaacagtg gagtcttctt tagtgccagt     2820

ccttgtggtt gaataaaaag gatggtccgc tttctattga gctgagaaat ctttgaagtg     2880

ggagttatta tctgagacat tcctgcttgt cgtcctaaca acgctgatga aacgtaaaag     2940

gttctttgtc agcgatttgt tctcctctct gtcaaactcc ctctgccccg ttagtttcaa     3000

accgtttcta aagagataaa aatcaaactt cttttaaaac aatatccaca cactgcatca     3060

atacataact ttaggtctaa gtcttgctaa gggataaaca aaagcaatgc ctagacatca     3120

gggtcagggc ctggtctggt gaagtatgca gaagttgggg ggccctcggg acaagctttg     3180

ggacatgagg aaaagaatgc agagagggtg caagcagaat acatacccta agtccataat     3240

tgtgtttctg cttctttctg ctctggtttg cattcaatca gcccaagttg ggtcacatag     3300

atgggtttcc tttgggtacc cctcaggctc ctaatattct tgcccaggat ccttggaact     3360

taagaatgca gccaagcaat tgttaatatc tcctgctcct tcaaagccac ctctgctaaa     3420

aatagaccca ttgtgtgttt cttctcacta gcagcaatca acaagccctt tctgccgtta     3480

ataagaagga gaatagctga aggagagaga tattttatta atttcctgtt tccttcagaa     3540

tcttggcaat tgaagtttag aaggtttggt ctacaacaca gtgatcgaaa atgcatgtaa     3600

atgcccatcc ttcccttcat tcacgtgtga agttgttcat tttatattgt gcccagcaaa     3660

gaaactttca cccagttcag gtttccccaa aactcctgtg gtggttttaa aggtggttta     3720

aataaataag gatgtgctgg tccccctact ctgtgtgtgc tgaataaatg gcttgtaaag     3780

aagtttttcc aagctgtaac ccatgctgtt attatagttg ctgcaaaatg ttcttcctga     3840

tattgatttt atttgttaac tgaaggtctc catatgtttg tttatattgc taatttatga     3900

gaaaatgtaa taattgcaat gaatgtgaat tatacagaca ggcaaacatt ttgtaatcat     3960

aattcacata tacacaaaag cctggctgaa atctttagac tatttgtacc ctctctaccc     4020

acactgtttg tgatttatca tctgtctctt tagtgtcagt taaattatga actaacttga     4080

aaataaaagt tgtttgactg aaagtgattg ttgaatgaac aacaaagttg aaagccatgg     4140

cttgatcttg taaatatata aatgtaaatg atattaaatc tgtgattcct tttccctcca     4200

aaggcttttg tgtacatggc gctgcatttg gctattttct ttggaaataa ataatgtgat     4260

gtttctcttc ctcttttg                                                   4278


<210>  474
<211>  2041
<212>  DNA
<213>  homo sapiens

<400>  474
agccatttct actttgcccg cccacagatg tagttttctc tgcgcgtgtg cgttttccct       60

cctccccgcc ctcagggtcc acggccacca tggcgtatta ggggcagcag tgcctgcggc      120

agcattggcc tttgcagcgg cggcagcagc accaggctct gcagcggcaa cccccagcgg      180

cttaagccat ggcgtgagta ccggggcggg tcgtccagct gtgctcctgg ggccggcgcg      240

ggttttggat tggtggggtg cggcctgggg ccagggcggt gccgccaagg gggaagcgat      300

ttaacgagcg cccgggacgc gtggtctttg cttgggtgtc cccgagacgc tcgcgtgcct      360

gggatcggga aagcgtagtc gggtgcccgg actgcttccc caggagccct acagccctcg      420

gaccccgagc cccgcaaggg tcccaggggt cttggctgtt gccccacgaa acgtggcagg      480

aaccaagatg gcggcggcag ggcggcggcg cgggcgtgag tcaagggcgg gcggtgggcg      540

gggcgcggcc gccctggccg tatttggacg tggggacgga gcgctttcct cttggcggcc      600

ggtggaagaa tcccctggtc tccgtgagcg tccattttgt ggaacctgag ttgcaagcag      660

ggaggggcaa atacaactgc cctgttcccg attctctaga tggccgatct agagaagtcc      720

cgcctcataa gtggaaggat gaaattctca gaacagctaa cctctaatgg gagttggctt      780

ctgattctca ttcaggcttc tcacggcatt cagcagcagc gttgctgtaa ccgacaaaga      840

caccttcgaa ttaagcacat tcctcgattc cagcaaagca ccgcaacatg accgaaatga      900

gcttcctgag cagcgaggtg ttggtggggg acttgatgtc ccccttcgac cagtcgggtt      960

tgggggctga agaaagccta ggtctcttag atgattacct ggaggtggcc aagcacttca     1020

aacctcatgg gttctccagc gacaaggcta aggcgggctc ctccgaatgg ctggctgtgg     1080

atgggttggt cagtccctcc aacaacagca aggaggatgc cttctccggg acagattgga     1140

tgttggagaa aatggatttg aaggagttcg acttggatgc cctgttgggt atagatgacc     1200

tggaaaccat gccagatgac cttctgacca cgttggatga cacttgtgat ctctttgccc     1260

ccctagtcca ggagactaat aagcagcccc cccagacggt gaacccaatt ggccatctcc     1320

cagaaagttt aacaaaaccc gaccaggttg cccccttcac cttcttacaa cctcttcccc     1380

tttccccagg ggtcctgtcc tccactccag atcattcctt tagtttagag ctgggcagtg     1440

aagtggatat cactgaagga gataggaagc cagactacac tgcttacgtt gccatgatcc     1500

ctcagtgcat aaaggaggaa gacacccctt cagataatga tagtggcatc tgtatgagcc     1560

cagagtccta tctggggtct cctcagcaca gcccctctac caggggctct ccaaatagga     1620

gcctcccatc tccaggtgtt ctctgtgggt ctgcccgtcc caaaccttac gatcctcctg     1680

gagagaagat ggtagcagca aaagtaaagg gtgagaaact ggataagaag ctgaaaaaaa     1740

tggagcaaaa caagacagca gccactaggt accgccagaa gaagagggcg gagcaggagg     1800

ctcttactgg tgagtgcaaa gagctggaaa agaagaacga ggctctaaaa gagagggcgg     1860

attccctggc caaggagatc cagtacctga aagatttgat agaagaggtc cgcaaggcaa     1920

gggggaagaa aagggtcccc tagttgagga tagtcaggag cgtcaatgtg cttgtacata     1980

gagtgctgta gctgtgtgtt ccaataaatt attttgtagg gaaagtaaaa aaaaaaaaaa     2040

a                                                                     2041


<210>  475
<211>  6132
<212>  DNA
<213>  homo sapiens

<400>  475
agttcagaga gaggagaggg agaaggagag aggggcagag gggaagggag agagggagag       60

cacgcgagac ggaaaggagc gcctcagagt ctctgaagca cgcaagagat aaccgattag      120

gaatttttcg ggcaactgtc acccggatag ctgtcagaga atcatcatca ccgcaactct      180

gacgtttcct acaagaagtt agagacttaa gcagtattgg catcggatgg aaatggtatg      240

catgctgctg tggaaaatat ccctgagctg aagaagtgca actatgtgtt gtgtgtgcta      300

aatgcccaga agaacccaga cccagtgggt aagagagacg aaatgtggag agaatgacta      360

acgacaaatc cgtgaatttg ttctctggag ttgctaattt gccagcccga agcaacacat      420

tttacaagga ggaaacattt tgctgcttct gatttctccc caaactggtg ctaccagatg      480

catggctttc tatgtgttgg aacaaatcat tcctaactgc agcatactgg gaaaggggaa      540

aggttgaggc aactaaccgg ctgtctccaa ataagtgatg agatataatg catcctccag      600

tccatgcacg cttcctcttg caatttgtgc atcattcctc agtggaaacc tttaaaccct      660

aaaatccagg aaaagaaaat aaatacatta tcatggacct gagggatttt tacctgttgg      720

ctgctctgat tgcctgttta aggctggatt ccgcaatagc tcaagaactt atttacacta      780

ttagagagga attgcctgaa aatgtgccca taggaaacat accaaaggat ctgaacattt      840

ctcacatcaa tgctgccaca gggaccagcg ccagccttgt ctacagactg gtttctaaag      900

ctggggatgc ccctttggtg aaagtttcca gcagcactgg ggaaattttc acaacctcca      960

acagaataga cagagaaaaa ctctgtgctg gcgcctcata tgctgaggag aatgagtgtt     1020

tctttgaact tgaggtggtg atcctcccca atgatttctt caggctgatc aaaataaaaa     1080

taattgtcaa ggataccaat gataatgccc ccatgtttcc atctcctgtc atcaatattt     1140

ccattccaga aaacactttg atcaacagcc gctttccaat tccatcagca acagatcctg     1200

acacaggctt caatggtgta cagcattatg aattgttaaa tgggcagagt gtttttggac     1260

tggatatcgt ggaaactcca gagggagaga agtggccaca actgattgtt cagcaaaact     1320

tggatagaga acagaaagat acctatgtga tgaaaatcaa agtagaggat ggaggcactc     1380

cacagaaatc cagtacggcc atactgcagg tcacagtaag tgatgtaaat gacaacaggc     1440

cagtgtttaa agagggtcaa gtggaggtgc atattccaga gaatgctccc gtaggtacct     1500

ctgtaattca gctccatgcc actgatgcag atataggcag taatgctgaa atccggtaca     1560

tttttggtgc ccaggtcgcc cctgcaacca aaagactctt tgctttaaat aatactactg     1620

ggctgattac agttcagagg tccttagata gagaggagac agccattcac aaagtgacag     1680

tgctggctag tgacggcagc tccactcctg ctcgagcaac ggttaccatc aatgtcaccg     1740

atgtaaatga taaccctcct aatatagacc tcaggtacat tataagtccc atcaatggca     1800

ccgtgtattt atctgagaaa gatcctgtca atacaaagat tgccctaatt acagtttcag     1860

ataaggacac agatgtgaat ggcaaagtga tctgttttat tgaaagagag gtcccatttc     1920

atttgaaggc ggtatatgac aaccaatatt tgttagagac ctcttctttg ttggactatg     1980

agggcaccaa agaattcagc tttaaaattg ttgcctctga ttctgggaag cccagtttaa     2040

atcagactgc cctggtaagg gttaagcttg aggatgaaaa tgacaaccca ccaattttca     2100

accagcctgt aattgagctg tcagtttctg aaaacaaccg acgtgggtta tacttaacaa     2160

ctattagtgc cacagatgaa gacagtggga aaaatgcaga cattgtttat cagcttggac     2220

cgaatgcctc cttctttgat ctggaccgaa aaacaggagt tttgacagcc tccagagtat     2280

ttgacagaga agaacaagaa cgattcattt ttacagtaac tgccagggac aatgggaccc     2340

ctcccctcca aagccaagcg gctgtgattg ttactgttct ggatgagaat gacaatagcc     2400

ccaagtttac tcataatcat tttcaatttt ttgtgtctga gaatctgcca aagtatagta     2460

ctgtgggggt aatcacagtg acagatgcag atgctggaga gaataaagct gtgactcttt     2520

ccattctaaa tgacaatgat aattttgtgt tggatcccta ttctggagtc ataaagtcaa     2580

atgtctcatt tgatagagag cagcagagtt cctacacttt tgatgtcaaa gccactgatg     2640

gaggacaacc acctcgttcc tctactgcaa aagtaactat caacgtcatg gatgtcaatg     2700

acaacagccc agttgtcatt tctccaccgt ctaatacttc ctttaagttg gtgcccctct     2760

cagccattcc tggctccgtg gtagcagaag tttttgcagt ggatgttgac actggaatga     2820

acgctgaact aaagtatact atagtgagtg gaaacaataa aggcttattc cggattgatc     2880

cagtaacagg taacattact ctggaagaaa aaccagcacc tactgatgtg ggattgcatc     2940

gtttggtggt caacataagt gacctggggt accctaagtc tttgcacacg cttgtgcttg     3000

tattccttta tgttaacgac actgctggaa atgcctccta tatctatgac ttgatccgca     3060

ggactatgga gaccccgttg gacaggaaca taggggatag tagccaaccc tatcaaaatg     3120

aggactatct aaccatcatg attgccatca tcgccggtgc catggtggtc attgttgtga     3180

tcttcgtcac cgttctggtg cgctgtcgcc atgcatcaag gttcaaagca gctcagagga     3240

gcaagcaagg tgccgaatgg atgtccccaa accaggagaa caagcaaaac aagaaaaaga     3300

aaagaaagaa aaggaagtct cccaaaagct ctcttttgaa ctttgttact atcgaagagt     3360

ccaaacccga tgatgcagtt catgaaccta tcaatgggac aataagcctg ccggctgaac     3420

tggaggagca aagtatagga agatttgact ggggcccggc acctccaaca acattcaagc     3480

ctaacagtcc tgacctggcc aagcactaca aatctgcttc tccacagcct gcttttcatc     3540

tcaaaccaga cactccagtt tccgtgaaaa agcaccacgt gattcaggaa ctccctttgg     3600

acaacacctt tgttgggggt tgtgacaccc tttctaaacg ctcttccact agttcagatc     3660

acttcagtgc ctcagagtgc agttcccaag gaggcttcaa gacaaagggc cccttacaca     3720

ccagacagtc gcagcgccgt gttacgtttc atctccctga tggctcccag gaaagctgca     3780

gtgacagtgg tctaggagac catgagccgg tgggtagtgg aaccctgatc tcacaccctc     3840

ttcctctggt tcagccacag gacgaattct atgaccaggc ctctccggac aagaggactg     3900

aagcagatgg caactctgat cccaactctg atgggccttt gggtccccga ggattagctg     3960

aagctacaga gatgtgcact caagagtgct tggttttggg tcactctgat aattgctgga     4020

tgcctcctgg cttgggtcca tatcaacacc ccaaatctcc tctctcaacc tttgcacccc     4080

agaaagaatg ggtgaagaag gacaagcttg tgaatgggca caccctgacc agagcctgga     4140

aagaagacag caacaggaac cagttcaatg accgtaagca gtatggctcc aatgaaggcc     4200

atttcaacaa tggcagccac atgacagaca ttcctctggc aaatctgaag tcttataagc     4260

aagcaggagg tgctactgag agtcctaagg agcaccaact ctaagaaaag gctatatggg     4320

acctaataac tttaaataga catgctaata ccgtgtgcgt cagagcttta tgtattcaat     4380

agatctctac aactatgccc cttctagcag ggatacctat aactttgtgt tagcaccatg     4440

gagaatacaa tgtttttgca acatatgaga gaagatagtt ctagccatgc aattttgttt     4500

actagaattg attacactct ccagagatct ctccattgtg caaatttttt ttattattgc     4560

attttatttt gaccctggac tgctgctatg aacaatagaa tatgcatttg gaaagtaaga     4620

aagtttcatg gattagagtg actgaaaaac atatccagtt agaaaattgt gctttttttt     4680

tttttttttt ttttttttgt cattgatttg tgctgggact gctatacttg acattatact     4740

gcaaacaaaa cttaaagaga taagcattaa acctattgtg ctgttaacaa cgttagtgga     4800

cacttgtaag tcaatcagtg ttaaagtatt tgtaaataga agcaagctat tattaacaac     4860

ttttgtgtac ttataatgtt cacctaaaaa tgttgtagca taattctgtg ttttatggtt     4920

gcttctgtcc ttctttttat ttacctcttt gttgttattt ttgttgtttc tttcagtgag     4980

gtgtttctgt gttagtagtc tgtcttgaca cacattgttc aaacaatctc aagcacttgt     5040

gtttaaaaaa ggttctgaaa tcttgcttct catatgatag cttatgatgc cggaattctg     5100

taaacaataa agatgaaaga aaaaatgaaa actttataca aaaaaggact tctgcaaaag     5160

cttggaaatt cagaacctat tttttatcat cttattttca aagtaggcaa aagcaaaatc     5220

acttaattag taccattaag tgagagagta atggaaaact gttatccatc aaaagtgata     5280

taatatcctg tacttgtcac tcatgtaaaa ctaatgtatc aaaattagca tatatggaag     5340

aaaaatcact attcaaaaat agtttcaatt gggcaaatgt gtgtctacaa ctttgttgaa     5400

atggcagagt ctgtgttgat cctcatatac aataatgttg ttgtaacaca agtgttatta     5460

gaccatagcc acaaaatatt taatgtgttg tgccttcatg atgtaacaga acattctcca     5520

ggtagggtag ttgggggaaa taaagggata aatctctaat tattgctgtt taactgtttg     5580

ttatcatagt tggtcaatgc ctggcaggta ccagcatatt gtcacttagg tcaaaccaat     5640

aaagtgacaa ctaatgttaa taagatctca gttgcacgtg caaacaaatc caaattcgaa     5700

cattcttagg aggtttttgt taaggcatga cagatgattt aaacaaataa atagcatgca     5760

acaaaatgtc tttattgaaa gaagtggaag ttatcttaat gccacggttc accatcaatt     5820

taaaagtaaa aaaaacaaaa aaaaaacaaa aaatttaaaa aaaaggtttg ctaatctgat     5880

agttaatttg ttcttaccaa aaaataaaat tactttgtaa atagcagttc acatttttcc     5940

acagtataat ggaaaataat gggtaggggt gcattgctta ttgaagtaca tttttgtcgg     6000

tttgtgaggg gtgtttgatg actttgacag aataaatatc taaacaatta tccttgttac     6060

tgctttgcca gttctacgtt atttacaatt attcagctct tgcaataaat gttctgaatt     6120

cctgaaaaaa aa                                                         6132


<210>  476
<211>  2955
<212>  DNA
<213>  homo sapiens

<400>  476
gggcgggcct cagacacact atgcgggttg cggggcctgg gggccggacg gctgtttcct       60

gtcctggtgc atggtggtcg gacgaaggaa ttgttggaaa attttctcgg aggtagaaga      120

tgttgttagc ccaaataaat cgagattctc agggaatgac agagtttcct ggaggaggga      180

tggaggcgca acatgttacg ctgtgcttga cagaggcagt caccgtggca gatggtgaca      240

acttagaaaa tatggaaggc gtaagcttgc aagcagtaac acttgcagat ggttctactg      300

cttacataca acacaattct aaagatgcaa aactcataga tggccaggtc attcagttgg      360

aagatggttc tgcggcctat gttcaacatg tacccatacc taaaagtaca ggggacagtt      420

tgcgtctaga ggatggtcaa gcagtacagt tagaagatgg taccacagca tttattcacc      480

acacctccaa agatagttat gaccagagtg cattacaggc ggttcagctg gaagatggta      540

ccacagctta tatccaccat gcagtgcaag tcccgcagtc tgacaccatc ttggcaattc      600

aggctgatgg gacagtggca ggtctgcaca ctggggatgc tacaattgac cctgacacca      660

tcagtgcttt ggaacagtat gcagcaaagg tgtccattga tggaagtgaa agtgtagcag      720

gtactggaat gattggagaa aatgagcaag agaaaaaaat gcagattgtt ttacaaggac      780

atgctacaag agtaactgct aaatctcaac agagtggaga gaaggcattt cgatgtgaat      840

atgatggatg tggaaaatta tatacaacag ctcatcatct caaggtccat gagaggtcac      900

acacaggaga tcggccttat cagtgtgagc atgcaggctg tgggaaggca tttgcaacag      960

gttatggatt aaaaagtcac gtcagaactc atacaggaga aaagccatat cggtgttcgg     1020

aagataattg tactaaatct ttcaaaactt caggagatct acagaaacac atcagaactc     1080

atacaggaga aaggcccttt aagtgtccct tcgaaggctg cggtcggtcc tttacaacat     1140

caaatatcag aaaagtgcac gttaggacac acacaggaga aagaccttat tactgcacag     1200

agccaggatg tgggagggca tttgccagtg caacaaatta taaaaaccat gtgaggatac     1260

acacaggaga aaagccatat gtttgtacag ttcctgggtg tgacaaaagg tttacagaat     1320

attccagttt gtacaaacat catgttgtcc acactcattc caaaccttac aactgtaacc     1380

actgtgggaa gacatacaag cagatctcca cgctggccat gcacaaacgg acagcccaca     1440

acgacactga gcccatcgag gaggagcagg aagccttctt tgagccgccc ccaggtcaag     1500

gtgaagatgt tcttaaaggg tcccagatta cgtatgttac aggtgtagaa ggggacgacg     1560

ttgtttctac acaagtagcc acagtaaccc aatctggact gagtcaacaa gttacactca     1620

tatcccagga tgggactcag catgtcaaca tatctcaagc tgacatgcag gccattggca     1680

acaccatcac aatggtaacg caggatggca cgcccatcac agtccccgcc catgatgcag     1740

tcatctcctc agcaggaacg cactctgttg ctatggttac tgctgagggt acagaagggg     1800

aacaggttgc aattgtagct caagacttgg cagcattcca tactgcctca tcagaaatgg     1860

ggcaccagca gcatagccat cacttagtaa ccacagaaac cagacctctg accttagtag     1920

caacatccaa tggcacccag attgcagttc agcttggaga acagccatct ctggaagaag     1980

ccatcagaat agcgtctaga atccaacaag gagaaacgcc agggttggat gattaatcct     2040

cagaacaatg gagcaataaa gcagaaggag tctttcatct tctggcagca gaaatccatg     2100

aagcccgggc ccaggaaaat tagaagtttt ccattcctga tacactgtac acatttttat     2160

gcgagagtgg agaacatttt attcttgaca cttttgtgta tataaccctt ggaatagatt     2220

ctcagagtga ttcattgtgt acaaggaagt atgaaattag ggcaatacag taaattttca     2280

tgttactctt ttatcagatc acaaactcct agagtctaca tgcaagacta gtaaagtctt     2340

atggagtctt atgatggatt tttaacttcc cgtggaaaaa aaaataaagg ctgtatctaa     2400

aatatcaaag gttctatatg tcacacaatc gtaattccaa aagccattat ggataataaa     2460

gggtgtaaag ccttcagata tttccccagt tagtagagtg tctgcggttt ttgttctact     2520

atatgcttgt ccatttttat ttgtatctca tggtttgcag actgtttgaa taatttatag     2580

tttcccatcc ctgttaaaaa ccagctcttc aagctgaaat gctaattata ttggcattac     2640

attgaattat gtacaaaatt ataaaatttg gttatttaaa attaaaaagt taaatccagt     2700

ggttttgtta aagattttgc ttagtattca atttttatta ctgtttttta aaaataatga     2760

atcatcaaag tttaaccaca ggctggtgcc cgggataaca gtactgtaat tggaaatggc     2820

tttactctga aaattaggtt agtgggttgg tgtaaattat ttatttttgc ttatgtactt     2880

ttgttttaaa gcttatttac cccaaagttt attattaatt ttgaatacag caatttttaa     2940

aatgttaaaa aaaaa                                                      2955


<210>  477
<211>  8053
<212>  DNA
<213>  homo sapiens

<400>  477
aaaagggcgg tggggcgggg ggcggggcag ggagagggag agaaatccag cagacatcta       60

gctctgcctt tctttcccag ccacagccag ggtagggctg ataaggcgct gatgcgttga      120

tggcagcctt gcagagctag acctgcactt aacttgcagc tgcctcccga gcctccaaga      180

tgtccacgcc ctgggtgaca ggcggcaggg cgctgccccg tgctcccccg gctctgctcg      240

acagcagcac gcagtgagag cctcgccgcc gccgaggagc aactcatgta acggcacagc      300

caacaagatg aacggagctt tggatcactc agaccaacca gacccagatg ccattaagat      360

gtttgtcgga cagatccccc ggtcatggtc ggaaaaggag ctgaaagaac tttttgagcc      420

ttacggagcc gtctaccaga tcaacgtcct ccgggaccgg agtcagaacc ctccgcagag      480

taaaggttgt tgtttcgtaa cattttatac aagaaaagct gcacttgagg cccagaatgc      540

actgcacaat attaaaactt tacctgggat gcatcatccc attcagatga aacctgcaga      600

tagtgaaaag tccaacgctg tggaagacag aaaattgttc ataggaatgg tatcgaagaa      660

atgtaatgag aacgacatca gggtgatgtt ctctccattt ggccagatag aagaatgccg      720

gatcctccgg ggacctgatg ggctgagtcg aggctgtgcg tttgtcacat tttctacaag      780

ggcaatggca cagaatgcaa tcaaagccat gcatcagtct cagaccatgg agggctgctc      840

ttcacctatc gtggtgaagt ttgctgacac tcagaaggac aaagagcaaa ggcgcctcca      900

gcagcagctc gctcagcaga tgcagcagct caacactgcc acctggggga acctgacagg      960

gctgggcgga ctgaccccac agtatctggc gctcctgcag caggccacct cctccagcaa     1020

cctgggtgcg ttcagcggca ttcaacaaat ggcaggcatg aatgctttac agttgcagaa     1080

cctggcgacg ctggctgctg ctgcagctgc ggcccagacc tcagccacca gcaccaatgc     1140

aaaccctctc tctaccacga gcagcgccct gggagccctc acgagtcccg tggctgcttc     1200

aacccccaac tccactgctg gtgcagccat gaactccttg acctctctcg ggactctgca     1260

aggactggct ggagccactg ttggactgaa taatattaat gcactagcag gtaccatcaa     1320

cagtatggcg gctctgaatg gaggacttgg cgccacaggc ttgacgaatg gcacggctgg     1380

caccatggac gccctcaccc aggcctactc aggaattcaa cagtacgcag ccgccgcgct     1440

gcccactctg tacagccaga gcctgctgca gcagcagagc gctgcaggca gccagaagga     1500

aggtccagag ggggcaaacc tctttattta ccaccttcca caggaatttg gagaccagga     1560

cattctgcag atgttcatgc cttttggaaa tgttatctct gctaaagtct tcattgacaa     1620

acagaccaat ctgagcaagt gctttggttt tgttagctac gacaatccag tctctgcaca     1680

agctgctatc caagctatga atggctttca gatcggcatg aaacgcttga aggtgcagct     1740

gaagcgttcc aaaaacgaca gcaaacctta ctgatcctaa ccccagaggc tccctgctct     1800

cattttagct ttcttaggac atcttcatgc ccgttagttc atcgtttgcc tagcatgtcc     1860

ctgtggcgtc tcaaaaaaaa gtttcatcgt cccgtcattg tttctgatgt ctttctgacc     1920

tcacatcata tttggttctc ctactgacct ttgatctagt ttgacctttg aaatttgcat     1980

gtgacctcat ctagctatga attctgggaa gtcaatgtga aaaacattgc tgcattcatg     2040

caagactgaa atttattatt agacaaattc attatagaaa aaacctgtgg caaaaacgtt     2100

tctttcttat tttttttctt ttcctaaaac agacttgaaa gtattataca gggattggca     2160

ttcttcccgg tcactggtaa caatagcaat atgtgtccag ggacacagaa tgttggtttc     2220

taacagacta cttccaaaaa cagtttgaga aaaaaactgt ctgattttaa gtctctagag     2280

gtctgtaata gtttttacat ttttcaggca gtgtaaagtt ttttgataag gccattttag     2340

gtggctcact ttctcattaa gatatatata tagaaccact ttttgtagat tagtataaga     2400

aaaatattta ccctgttttg gggcaaatgc tacctatttg tgtcaccttt tgctgaactc     2460

acagttagac aatccatggt ttaatgcaca tgaaattacc tatattttat actgtttcaa     2520

tgtacaggag aaaggttact gtaaactgtg ttatgttggt gcttctgtga attaagttgt     2580

ggtttcatca tgagtcttaa tgttctttgt tgataagaca agtttagaat tggtttactt     2640

aatacaaaaa aaaaaaaaag aatttcaaaa aaaaaagttg tttgcttaaa aaaaatttca     2700

tgtgagggaa aaaaaaaaaa cctattccag aataagtttt gtgttggctt gtgaagcatt     2760

gatgtcattt tttttaattg tggactattt agatgtgttt gtgttcagca aaatgtgatc     2820

tgtttttttc ttttaaagaa aaaaagtgaa aatatatagt gccaaattcc aaaggtactt     2880

ccttcctaga gcttcagtgt gtttcttgtg agaagtaatt tgataacatg ggtattttat     2940

tatgtgtttt gtataaatcc ctaatattta aaaaaaaaaa caaaacaaaa aaaggttaca     3000

aagtttgtta acttgctatc ctgtggtctt gttgcctgaa attgttattg tttgttattt     3060

ctctctgatg ttttttgtaa gacattgtat aagtgcccat gtcccacttt tttaaccact     3120

ccgcacatca gtgctgtgaa ggcaacctca ccatgtattt tcttcataat ctatggaaac     3180

ctctaaggtg agaaagtttt gaacttttaa ccctttctac ccagagctat ctggaatgtt     3240

gatgactttt tatactgtca tgatttgagt ttgttttggg gtgtttccaa tttggatttt     3300

tttccctgca tctatcctct aagttgtttc ggtttgacta ctttgttctt tggttaagat     3360

ccaaaagaaa acagaaaaca attccacgag gccaatctaa agggaaaaaa tcctacacta     3420

cttttactac ttttgattat ttctcatttt tgggaaaaga attcctaatg tgctactaga     3480

attccttctt cagttttaac gagtaattgg ataaaccctg agggaaaacg gaggtagatt     3540

cagcacctaa caatcctgta tgcttttgag atcacgttta gtgctatgtc ctagtctaga     3600

atattttcat ataccttgca gtaaaacgac tttgtggcag gacagtctct tgaggggttt     3660

tgtttctgtt tcctaaatac tcctaaataa tatttctaat cagccattat gctggggcat     3720

ctctgatccc agtaggtacc tctgaatata ccaggtgtct ggagttagaa gcccatagcc     3780

ctttcccagc ctttttggtt tttttaattg aacacatttc atctaagtaa agctcagttc     3840

tttatcacaa tttactgacc aaatacctag caccagttcc tgctgccact ttttaaagtg     3900

ccatatgact ttctacgaac aggtaccttg ctgtcttgac aaatcctaat gtcacgccta     3960

cagccccaac acaagctcca gtcttcctct tcggcatgcc ctggaagctt cttggcctca     4020

gctccccttc cccgctcagc accctgttag gatcagtgtg tgtggatggg atagccctgg     4080

gatggaaagg actagcctct actgatgcaa aaaaacaaaa agcaacacaa acgtttcctt     4140

cttatagcac atgcacttcc ttacaatgac atgatttgta ttatcctcac atgtgtttac     4200

tactgctggg gccttccttc atcctctgag ggctattttg tactttctgc agcaatcagc     4260

ttaataacaa cacttattgc acctgtctct ctctgagaac acggtgtgtc tcgacacgta     4320

ccacgtacgt ggaaacacaa gagcccacca cttgaatttc taagaccatt tcattctgaa     4380

acttcttatc aattacctaa atctcaacga aaaacaattt actgaagccg actcccctcc     4440

ccatctccct ctcaacctca acccacctgc atgcatctcc cccagaggaa acactgaggg     4500

taggggacag gaggctcagg acgcgccctc tgaatcgagt gtttcttctt cacaagtcac     4560

caagagagga catgaggggg aaagtccttt tttgcccttc tccaaaaaat aaccttccac     4620

agagacaaac tgtccttcta tccactttta tcttttaata aatatcaaaa ggaaaaagct     4680

gcaagggtgc aaagggcctg tgccagaaga aaacacacac agggaaaccg ctttttttaa     4740

tcaattgtag agaatagtca tttttaatct aaattagaga attgtgatac aatggcagtc     4800

ctcaaaggcg taacgagttc atctttcttt caccataggg gttatagttg gcttgtgcta     4860

ctctggaatc attttactgt ttgtttttat tatcttaagt gctaattaaa aaaaaaataa     4920

aattttaaaa aaacctgtag tttcattacc tttttgaata atgtcataca aaaaatgtat     4980

ttgttttttt gtgctgtgag aattgatgtt tgtagattaa taatcatttt gtttagaatt     5040

acaaaatagt ttttaaatat tgtctgagaa aagccaaagt taatgcaacc tagtggaaac     5100

tgtaagacca tttgagtatt gtttgtttta ttgatgcatt tggattttgt tgtttgatgg     5160

aatttgagcc aaaaaaaaaa tacgcaggct ttcctatttc tacaactgat tgtacttatg     5220

cattttgtac cagtggaact ttttatactg gagattaaaa aaaaaatgga aatttttgtg     5280

gcttgctctg gtgggcccct gacaatgact gatttcaagt ttgatttcgg gttgattgat     5340

tgattgattg atagaaagaa agttgctttt cttttgagaa ttaaaaactt tggcttgatt     5400

tcttttttcc ctttgcttat atctagcatt agaattttgt cttaaaataa cagcggtaag     5460

tttcactttt tattctgtat tgtgcagtta cacaataagg taattagatt tagaagtact     5520

cagtcacttt aagtggataa atgtattagt taaaacttta gggtttgctt ttttgctgtt     5580

tagatcaaag ttttttctga ttcttctgtc ctcattgtga acataaccgt gtagttgaaa     5640

cagtcaaact tatttttgta atgtatgtta ttgtgtgatg cagttttttg cttctgtctc     5700

caatattaaa ccattttcct aatacttgtt tctctctctg cgtgttgtat tgttggtagt     5760

cattatatgt tggtgataca tctgcacacc tcactgtttc acgtatctgt ttttttctct     5820

atgttgtgta aaaagataca gtcgattcca cttaagtgaa tatctgattt ggggaagagg     5880

aaactgcaca gcagccacct ttgatttatg tacaaccgcc cacttgaact cctgcttcca     5940

agatttatac acttttttcc tacagttcac ctcagtaact gcctttgggg ttggatttgc     6000

caaggtgttt tacggtcttt tgaccacaca ggttaatttc cccttctctc ccctccctca     6060

tgagtctatc cacgcagttc ttaacataca ttccaaactg ctgcggggtt tcctctccac     6120

acccacgagg ccaaacccgc atcattacag tccaactctt cttagacact aatcactttc     6180

taaaagaagt gagttctcca gggaagaaaa atcaacttag ccagtgaaaa gggttaaact     6240

taagtctatt atttgttgcc ctcaatcaaa agatatgtat agaaaagtca tttaaattat     6300

ttatttctac aagctaattg aatccaggag cagctttaat tattaacact aacggaagag     6360

aaaagaagta tttccaaggg ctcaaatgga agctgtactc agtccggtgg aggcaggggg     6420

aggtaaagtt tctcacactc aagtcgtctt catagtttac tgtccttttc caaacaaaag     6480

ctaataacgc catacgcatc cacacactcc ctcctggatg aacctaagtc tcgtccccac     6540

tgtcacccca aggccagtta tcaaaaactg ttccttctct gccctcaaag actgaagccg     6600

caggccctgt tctgcctctg ctcaggaatc tgattgctct taaagtgctc ttacaagatt     6660

ccgtcgatgt ttgctccctc tgtcttatct ctccttccag tattttcaga cgcacaagct     6720

ctgactcagg ccacccagca cctggcagcc ttcctctgcg tgccagtgaa atctctccca     6780

gtaggtgctc aggctcttca ccctctcgtt gcagcagccc ctctggcccg agattgtatt     6840

ttctagtctg ctcaagaaca gaggggcctg gcgaggtgga ggaagggagg ctccctcccc     6900

ggggctggcc gcctcagtga tggtgatgcc accagctcca gcctgcacgg atggagctca     6960

cttcctacca tcacttctgc tttcagtctc ctcatagcct tcggcagtct cctctgaaaa     7020

cacactgcct acgttagtgg gaaaggatgg ctaagggtgt gatttctttt tattagggag     7080

gtgggagggg gatgttggga ggcatggggg gtgattaaat tatcatttcc aaggtgcaag     7140

tgtttatttt tcaaatctat aagtacatag ttccaccatt ttggcacaag acaaaatact     7200

catgctaagc aaaggaagag aaagacaaag ccagtttttg ttgcttttct aaagcaacaa     7260

ataattctcc aaagaagggg atgaaaatgc tagttccttt aagcacttac tgactgtaaa     7320

gttggtccct gcttaaattc atacccatag ttttgagtcg gtatgacacc actgcagtgt     7380

gagcaaggtg aatccgtgtg ccatgcatgg accaccttgg gataccgcag caccatcaac     7440

atccgccttg ctgatggaag ccacacacgc tgcccagccc acagcagtcg cacgcagccg     7500

atgggctcgg actcttagct ggcaggctag gacacacagt gaacattaat gtactgtgaa     7560

tcgttcctga taagtgaata aaacattgtg accaaacaat cagcttattc acttatcagg     7620

aatcgactgt tctgctaatt tgctgttgtt gtttttcatc tctgttgtag ttcactattt     7680

ttgctgtgtt ctgttttctc ctctcatgct tgggcaaatc actgggaata ttatcttcat     7740

gtgaccatga aacgtttcta ttgagtgaaa atgatatctt aacaaaatct atgcacttgc     7800

tatcaggaac acaatactgg atgtgtctta tatatattga actatatagt actcgatttc     7860

ttaaataaag cttaagaaag gactctgttg tgtgtaaagt taatgtgatt atttttcaaa     7920

gcagtgtttc taaggggtat ttttgttctt ttaagtcttg agtgatacag gatatttttc     7980

attaaaatta tatcactggc tttatgactt aatattcaat aaattgactt tggaaacaaa     8040

aaaaaaaaaa aaa                                                        8053


<210>  478
<211>  6132
<212>  DNA
<213>  homo sapiens

<400>  478
agttcagaga gaggagaggg agaaggagag aggggcagag gggaagggag agagggagag       60

cacgcgagac ggaaaggagc gcctcagagt ctctgaagca cgcaagagat aaccgattag      120

gaatttttcg ggcaactgtc acccggatag ctgtcagaga atcatcatca ccgcaactct      180

gacgtttcct acaagaagtt agagacttaa gcagtattgg catcggatgg aaatggtatg      240

catgctgctg tggaaaatat ccctgagctg aagaagtgca actatgtgtt gtgtgtgcta      300

aatgcccaga agaacccaga cccagtgggt aagagagacg aaatgtggag agaatgacta      360

acgacaaatc cgtgaatttg ttctctggag ttgctaattt gccagcccga agcaacacat      420

tttacaagga ggaaacattt tgctgcttct gatttctccc caaactggtg ctaccagatg      480

catggctttc tatgtgttgg aacaaatcat tcctaactgc agcatactgg gaaaggggaa      540

aggttgaggc aactaaccgg ctgtctccaa ataagtgatg agatataatg catcctccag      600

tccatgcacg cttcctcttg caatttgtgc atcattcctc agtggaaacc tttaaaccct      660

aaaatccagg aaaagaaaat aaatacatta tcatggacct gagggatttt tacctgttgg      720

ctgctctgat tgcctgttta aggctggatt ccgcaatagc tcaagaactt atttacacta      780

ttagagagga attgcctgaa aatgtgccca taggaaacat accaaaggat ctgaacattt      840

ctcacatcaa tgctgccaca gggaccagcg ccagccttgt ctacagactg gtttctaaag      900

ctggggatgc ccctttggtg aaagtttcca gcagcactgg ggaaattttc acaacctcca      960

acagaataga cagagaaaaa ctctgtgctg gcgcctcata tgctgaggag aatgagtgtt     1020

tctttgaact tgaggtggtg atcctcccca atgatttctt caggctgatc aaaataaaaa     1080

taattgtcaa ggataccaat gataatgccc ccatgtttcc atctcctgtc atcaatattt     1140

ccattccaga aaacactttg atcaacagcc gctttccaat tccatcagca acagatcctg     1200

acacaggctt caatggtgta cagcattatg aattgttaaa tgggcagagt gtttttggac     1260

tggatatcgt ggaaactcca gagggagaga agtggccaca actgattgtt cagcaaaact     1320

tggatagaga acagaaagat acctatgtga tgaaaatcaa agtagaggat ggaggcactc     1380

cacagaaatc cagtacggcc atactgcagg tcacagtaag tgatgtaaat gacaacaggc     1440

cagtgtttaa agagggtcaa gtggaggtgc atattccaga gaatgctccc gtaggtacct     1500

ctgtaattca gctccatgcc actgatgcag atataggcag taatgctgaa atccggtaca     1560

tttttggtgc ccaggtcgcc cctgcaacca aaagactctt tgctttaaat aatactactg     1620

ggctgattac agttcagagg tccttagata gagaggagac agccattcac aaagtgacag     1680

tgctggctag tgacggcagc tccactcctg ctcgagcaac ggttaccatc aatgtcaccg     1740

atgtaaatga taaccctcct aatatagacc tcaggtacat tataagtccc atcaatggca     1800

ccgtgtattt atctgagaaa gatcctgtca atacaaagat tgccctaatt acagtttcag     1860

ataaggacac agatgtgaat ggcaaagtga tctgttttat tgaaagagag gtcccatttc     1920

atttgaaggc ggtatatgac aaccaatatt tgttagagac ctcttctttg ttggactatg     1980

agggcaccaa agaattcagc tttaaaattg ttgcctctga ttctgggaag cccagtttaa     2040

atcagactgc cctggtaagg gttaagcttg aggatgaaaa tgacaaccca ccaattttca     2100

accagcctgt aattgagctg tcagtttctg aaaacaaccg acgtgggtta tacttaacaa     2160

ctattagtgc cacagatgaa gacagtggga aaaatgcaga cattgtttat cagcttggac     2220

cgaatgcctc cttctttgat ctggaccgaa aaacaggagt tttgacagcc tccagagtat     2280

ttgacagaga agaacaagaa cgattcattt ttacagtaac tgccagggac aatgggaccc     2340

ctcccctcca aagccaagcg gctgtgattg ttactgttct ggatgagaat gacaatagcc     2400

ccaagtttac tcataatcat tttcaatttt ttgtgtctga gaatctgcca aagtatagta     2460

ctgtgggggt aatcacagtg acagatgcag atgctggaga gaataaagct gtgactcttt     2520

ccattctaaa tgacaatgat aattttgtgt tggatcccta ttctggagtc ataaagtcaa     2580

atgtctcatt tgatagagag cagcagagtt cctacacttt tgatgtcaaa gccactgatg     2640

gaggacaacc acctcgttcc tctactgcaa aagtaactat caacgtcatg gatgtcaatg     2700

acaacagccc agttgtcatt tctccaccgt ctaatacttc ctttaagttg gtgcccctct     2760

cagccattcc tggctccgtg gtagcagaag tttttgcagt ggatgttgac actggaatga     2820

acgctgaact aaagtatact atagtgagtg gaaacaataa aggcttattc cggattgatc     2880

cagtaacagg taacattact ctggaagaaa aaccagcacc tactgatgtg ggattgcatc     2940

gtttggtggt caacataagt gacctggggt accctaagtc tttgcacacg cttgtgcttg     3000

tattccttta tgttaacgac actgctggaa atgcctccta tatctatgac ttgatccgca     3060

ggactatgga gaccccgttg gacaggaaca taggggatag tagccaaccc tatcaaaatg     3120

aggactatct aaccatcatg attgccatca tcgccggtgc catggtggtc attgttgtga     3180

tcttcgtcac cgttctggtg cgctgtcgcc atgcatcaag gttcaaagca gctcagagga     3240

gcaagcaagg tgccgaatgg atgtccccaa accaggagaa caagcaaaac aagaaaaaga     3300

aaagaaagaa aaggaagtct cccaaaagct ctcttttgaa ctttgttact atcgaagagt     3360

ccaaacccga tgatgcagtt catgaaccta tcaatgggac aataagcctg ccggctgaac     3420

tggaggagca aagtatagga agatttgact ggggcccggc acctccaaca acattcaagc     3480

ctaacagtcc tgacctggcc aagcactaca aatctgcttc tccacagcct gcttttcatc     3540

tcaaaccaga cactccagtt tccgtgaaaa agcaccacgt gattcaggaa ctccctttgg     3600

acaacacctt tgttgggggt tgtgacaccc tttctaaacg ctcttccact agttcagatc     3660

acttcagtgc ctcagagtgc agttcccaag gaggcttcaa gacaaagggc cccttacaca     3720

ccagacagtc gcagcgccgt gttacgtttc atctccctga tggctcccag gaaagctgca     3780

gtgacagtgg tctaggagac catgagccgg tgggtagtgg aaccctgatc tcacaccctc     3840

ttcctctggt tcagccacag gacgaattct atgaccaggc ctctccggac aagaggactg     3900

aagcagatgg caactctgat cccaactctg atgggccttt gggtccccga ggattagctg     3960

aagctacaga gatgtgcact caagagtgct tggttttggg tcactctgat aattgctgga     4020

tgcctcctgg cttgggtcca tatcaacacc ccaaatctcc tctctcaacc tttgcacccc     4080

agaaagaatg ggtgaagaag gacaagcttg tgaatgggca caccctgacc agagcctgga     4140

aagaagacag caacaggaac cagttcaatg accgtaagca gtatggctcc aatgaaggcc     4200

atttcaacaa tggcagccac atgacagaca ttcctctggc aaatctgaag tcttataagc     4260

aagcaggagg tgctactgag agtcctaagg agcaccaact ctaagaaaag gctatatggg     4320

acctaataac tttaaataga catgctaata ccgtgtgcgt cagagcttta tgtattcaat     4380

agatctctac aactatgccc cttctagcag ggatacctat aactttgtgt tagcaccatg     4440

gagaatacaa tgtttttgca acatatgaga gaagatagtt ctagccatgc aattttgttt     4500

actagaattg attacactct ccagagatct ctccattgtg caaatttttt ttattattgc     4560

attttatttt gaccctggac tgctgctatg aacaatagaa tatgcatttg gaaagtaaga     4620

aagtttcatg gattagagtg actgaaaaac atatccagtt agaaaattgt gctttttttt     4680

tttttttttt ttttttttgt cattgatttg tgctgggact gctatacttg acattatact     4740

gcaaacaaaa cttaaagaga taagcattaa acctattgtg ctgttaacaa cgttagtgga     4800

cacttgtaag tcaatcagtg ttaaagtatt tgtaaataga agcaagctat tattaacaac     4860

ttttgtgtac ttataatgtt cacctaaaaa tgttgtagca taattctgtg ttttatggtt     4920

gcttctgtcc ttctttttat ttacctcttt gttgttattt ttgttgtttc tttcagtgag     4980

gtgtttctgt gttagtagtc tgtcttgaca cacattgttc aaacaatctc aagcacttgt     5040

gtttaaaaaa ggttctgaaa tcttgcttct catatgatag cttatgatgc cggaattctg     5100

taaacaataa agatgaaaga aaaaatgaaa actttataca aaaaaggact tctgcaaaag     5160

cttggaaatt cagaacctat tttttatcat cttattttca aagtaggcaa aagcaaaatc     5220

acttaattag taccattaag tgagagagta atggaaaact gttatccatc aaaagtgata     5280

taatatcctg tacttgtcac tcatgtaaaa ctaatgtatc aaaattagca tatatggaag     5340

aaaaatcact attcaaaaat agtttcaatt gggcaaatgt gtgtctacaa ctttgttgaa     5400

atggcagagt ctgtgttgat cctcatatac aataatgttg ttgtaacaca agtgttatta     5460

gaccatagcc acaaaatatt taatgtgttg tgccttcatg atgtaacaga acattctcca     5520

ggtagggtag ttgggggaaa taaagggata aatctctaat tattgctgtt taactgtttg     5580

ttatcatagt tggtcaatgc ctggcaggta ccagcatatt gtcacttagg tcaaaccaat     5640

aaagtgacaa ctaatgttaa taagatctca gttgcacgtg caaacaaatc caaattcgaa     5700

cattcttagg aggtttttgt taaggcatga cagatgattt aaacaaataa atagcatgca     5760

acaaaatgtc tttattgaaa gaagtggaag ttatcttaat gccacggttc accatcaatt     5820

taaaagtaaa aaaaacaaaa aaaaaacaaa aaatttaaaa aaaaggtttg ctaatctgat     5880

agttaatttg ttcttaccaa aaaataaaat tactttgtaa atagcagttc acatttttcc     5940

acagtataat ggaaaataat gggtaggggt gcattgctta ttgaagtaca tttttgtcgg     6000

tttgtgaggg gtgtttgatg actttgacag aataaatatc taaacaatta tccttgttac     6060

tgctttgcca gttctacgtt atttacaatt attcagctct tgcaataaat gttctgaatt     6120

cctgaaaaaa aa                                                         6132


<210>  479
<211>  2639
<212>  DNA
<213>  homo sapiens

<400>  479
ggcgccttgg gaccgcgtgg gagccgcagc cgaaccgagt agggaccggg accgcgcggc       60

gccgccgtcc ccggccgggc ccggcccccg cgagccgagc gcgcgccccc gtcgcccacc      120

cgggcgcggc tggatgcggc ggggtccccg cggcggcgac ccccggcccc gagcgcccgg      180

agcgcccaga ggcggcgtgc ggggcccggg gacgccgcgc cctccatgcg ccgaggcgcg      240

ccccgagaca gccgggggcc cgcgccgcag ccgccgcccg cgctgagccc cggcccggcc      300

cgcggcccgc gcccggcggc agcatgagcc aggccgagct gtccacctgc tccgcgccgc      360

agacgcagcg catcttccag gaggctgtgc gcaagggcaa cacgcaggag ctgcagtcgc      420

tgctgcagaa catgaccaac tgcgagttca acgtgaactc gttcgggccc gagggccaga      480

cggcgctgca ccagtcggtc atcgacggca acctggagct cgtgaagctg ctggtcaagt      540

tcggcgccga catccgcctg gccaaccgcg acggctggag cgcgctgcac atcgccgcgt      600

tcggtggcca ccaggacatc gtgctctatc tcatcaccaa ggcgaagtac gcggccagcg      660

gccggtgatg cccgccggga ccccggaccc cggccctgcg cccgcgtcgt ctctgctgta      720

ccttcccgcc aactacctcg gtgcgcgccc ggctcgcagg ccccgccaga aggcccgtgg      780

ccacggcgaa tacggcgcgt gcgtcccggc cccagggtcc ggcagccccg ccggccgagc      840

gcctccctgc ggcctagccg ggcccggccg ggccggagca gcttcccacg gcccccaccc      900

gctcgcctgc ccgccgcctc gcgggtgggg gcggggcgcg ggctccagcc ccttttgaaa      960

tttgagtctc gcaaccagca agttcggaat cccgagatac cggatcctct gcgcaaaatg     1020

ttttctcccg aaggtgaaag gcgggcggcg ggagccgaag gcggactcgg agcgctccgc     1080

cgccgccttc aggacccgcc cgcaggcccg ggacgcgccg atgccggctg cagccgagga     1140

gcagccccga ggtccgaggt ccgcgccgct ggcgcgcggc cgaggagacg ctcggctgtt     1200

cgctgttgct ggtgttctaa actatttatc ttgtgtgtgt acatttgtgg gtggagtttg     1260

tgcgcctggt ttttttgttt ggaaaacact gcgtggtcaa tgtggttatg ggggggagtg     1320

atgcattttt ttctagtctt aaaactaaaa acttgagtct accatttctt ggttgcactg     1380

aaaataccgc ccagcctgat ggtgttcccg tgctgtccct cccccttccc ttctccccgc     1440

gtctacctcc ccaccccgtt ctgttccccc tccctccttc tccctctccc tcaaatccgt     1500

gagttttgga agccccaggg cctctctccc ccgcccctcc tggatgaggc caccatcccc     1560

caaaccggct tgttttgcag tttccccagg atcctggaag ctcgctggcg ctcgagggtg     1620

gcggggacac gggggggtgg gtgaaggttc gttacctttt ctagtgcgtt ctatcatagt     1680

taacggttgc acactttttt aaaaaaagta aatggatttg ccacaattaa atgtcataac     1740

atttatgaca gaatataaaa tattaacata ttttaagcca agttttaggt gtattttttg     1800

aatcttggtt ataaacccaa ttttaaaggg cgatgtatcc agcgttgtga aggcaacaga     1860

gtgtacccat atttatattt ttataaaata cctataagac tgtgaatctc ttgtgctaat     1920

ggctgagtta attgaaggat cgttttgccc ctttttagcc tcccagagct tcgaggactc     1980

aattcgaacc cgaaatcctg ccgtggggga ggggttgcgt cgagacctgg gcccggggag     2040

gttctcctgc gtcactttct gtcctgaaag gcgcccttcc tggtttctgt ggctccaatt     2100

ttctatgcag ccccacaccc cttgttgttt tgatcctgag aaataaaagg gaggctgaat     2160

tattcaaatt taaatgaggt ttccccttca tggaagtgct gctgaccctt cgtgcagaaa     2220

tggggagcac ttgaggacac aggtgggtgg aggccctttg tgcgtggctg gtcgtattcg     2280

ggcagccctc cgtcgctttt tataaaactt tgtgtgagaa gaatatattg ataatgtcag     2340

tgaaacaagc agacattgaa atggaggcac agattactcc acaaggagtt cttctgtata     2400

ttttttctag atgcaaatac ctttttaatt atgttaatta atgttaagac tttctaggct     2460

tatatcgaag ctgtgtgtgg gtcacggggt gatcactgct aactggataa agtttgtgca     2520

gcacattcct gagtgtacga tattgacctg tagcccagcg tgaaaaattt ataaataaat     2580

ttttcattga tctttttata ttaaaaaaaa gtttcttggt caaaaaaaaa aaaaaaaaa      2639


<210>  480
<211>  6322
<212>  DNA
<213>  homo sapiens

<400>  480
agtccgagcc tcagacgcgc gggcgcgggg gacggcgcag gggccgcctg gctggagcag       60

ccagagggga tagcttcgtc gagaacggag gacaccggcg gtccagggtc ctgggcagtc      120

gcgccagagc tgagcggagg gcgcggcgcg agaacgaatc tttgtgacat tctctctcag      180

cattctttat cccctgtttg ctgaagactt cgacaaaagc tggtcttagc tgttggcatt      240

ctcctgagaa aaggatagct tcagaaatca gaaaaacatt tgggaggtgt ctagcccagt      300

ggaccttctg aagagcaatg ctaagaagac gtttggttta aagaattaaa aggaagaaca      360

acttaagagc ttcttcaaag tttcccgcat gaaaattact taaacgttgc acacaacgtt      420

tcacaaaatc ttttgtgaaa gaagaaaagg aaattcagtg tgtgagtctc agcaggagtt      480

aagctaatgc agcttaaaat aatgccgaaa aagaagcgct tatctgcggg cagagtgccc      540

ctgattctct tcctgtgcca gatgattagt gcactggaag tacctcttga tctggtacag      600

cctccaacca tcacccaaca gtctccaaaa gattacatta ttgaccctcg ggagaatatt      660

gtaatccagt gtgaagccaa agggaaaccg cccccaagct tttcctggac ccgtaatggg      720

actcattttg acatcgataa agaccctctg gtcaccatga agcctggcac aggaacgctc      780

ataattaaca tcatgagcga agggaaagct gagacctatg aaggagtcta tcagtgtaca      840

gcaaggaacg aacgcggagc tgcagtttct aataacattg ttgtccgccc atccagatca      900

ccattgtgga ccaaagaaaa acttgaacca atcacacttc aaagtggtca gtctttagta      960

cttccctgca gacccccaat tggattacca ccacctataa tattttggat ggataattcc     1020

tttcaaagac ttccacaaag tgagagagtt tctcaaggtt tgaatgggga cctttatttt     1080

tccaatgtcc tcccagagga cacccgcgaa gactatatct gttatgctag atttaatcat     1140

actcaaacca tacagcagaa gcaacctatt tctgtgaagg tgatttcagt ggatgaattg     1200

aatgacacta tagctgctaa tttgagtgac actgagtttt atggtgctaa atcaagtaga     1260

gagaggccac caacattttt aactccagaa ggcaatgcaa gtaacaaaga ggaattaaga     1320

ggaaatgtgc tttcactgga gtgcattgca gaaggactgc ctaccccaat tatttactgg     1380

gcaaaggaag atggaatgct acccaaaaac aggacagttt ataagaactt tgagaaaacc     1440

ttgcagatca ttcatgtttc agaagcagac tctggaaatt accaatgtat agcaaaaaac     1500

gcattaggag ccatccacca taccatttct gttagagtta aagcggctcc atactggatc     1560

acagcccctc aaaatcttgt gctgtcccca ggagaggatg ggaccttgat ctgcagagct     1620

aatggcaacc ccaaacccag aattagctgg ttaacaaatg gagtcccaat agaaattgcc     1680

cctgatgacc ccagcagaaa aatagatggc gataccatta ttttttcaaa tgttcaagaa     1740

agatcaagtg cagtctatca gtgcaatgcc tctaatgaat atggatattt actggcaaac     1800

gcatttgtaa atgtgctggc tgagccacca cgaatcctca cacctgcaaa cacactctac     1860

caggtcattg caaacaggcc tgctttacta gactgtgcct tctttgggtc tcctctccca     1920

accatcgagt ggtttaaagg agctaaagga agtgctcttc atgaagatat ttatgtttta     1980

catgaaaatg gaactttgga aattcctgtg gcccaaaagg acagtacagg aacttatacg     2040

tgtgttgcaa ggaataaatt agggatggcg aagaatgaag ttcacttaga aatcaaagat     2100

cctacatgga tcgttaaaca gcccgaatat gcagttgtgc aaagagggag catggtgtcc     2160

tttgaatgca aagtgaaaca tgatcacacc ttatccctca ctgtcctgtg gctgaaggac     2220

aacagggaac tgcccagtga tgaaaggttc actgttgaca aggatcatct agtggtagct     2280

gatgtcagtg acgatgacag cgggacctac acgtgtgtgg ccaacaccac tctggacagc     2340

gtctccgcca gcgctgtgct tagcgttgtt gatgtcccaa atcctccctt tgacttagaa     2400

ctgacagatc aacttgacaa aagtgttcag ctgtcatgga ccccaggcga tgacaacaat     2460

agccccatta caaaattcat catcgaatat gaagatgcaa tgcacaagcc agggctgtgg     2520

caccaccaaa ctgaagtttc tggaacacag accacagccc agctgaagct gtctccttac     2580

gtgaactact ccttccgcgt gatggcagtg aacagcattg ggaagagctt gcccagcgag     2640

gcgtctgagc agtatttgac gaaagcctca gaaccagata aaaaccccac agctgtggaa     2700

ggactgggat cagagcctga taatttggtg attacgtgga agcccttgaa tggtttcgaa     2760

tctaatgggc caggccttca gtacaaagtt agctggcgcc agaaagatgg tgatgatgaa     2820

tggacatctg tggttgtggc aaatgtatcc aaatatattg tctcaggcac gccaaccttt     2880

gttccatacc tgatcaaagt tcaggccctg aatgacatgg ggtttgcccc cgagccagct     2940

gtagtcatgg gacattctgg agaagacctc ccaatggtgg ctcctgggaa cgtgcgtgtg     3000

aatgtggtga acagtacctt agccgaggtg cactgggacc cagtacctct gaaaagcatc     3060

cgaggacacc tacaaggcta tcggatttac tattggaaga cccagagttc atctaaaaga     3120

aacagacgtc acattgagaa aaagatcctc accttccaag gcagcaagac tcatggcatg     3180

ttgccggggc tagagccctt tagccactac acactgaatg tccgagtggt caatgggaaa     3240

ggggagggcc cagccagccc tgacagagtc tttaatactc cagaaggagt ccccagtgct     3300

ccctcgtctt tgaagattgt gaatccaaca ctggactctc tcactttgga atgggatcca     3360

ccgagccacc cgaatggcat tttgacagag tacaccttaa agtatcagcc aattaacagc     3420

acacatgaat taggccctct ggtagatttg aaaattcctg ccaacaagac acggtggact     3480

ttaaaaaatt taaatttcag cactcgatat aagttttatt tctatgcaca aacatcagca     3540

ggatcaggaa gtcaaattac agaggaagca gtaacaactg tggatgaagc gatggcaagc     3600

cggcaggtgg atattgcaac tcagggctgg ttcattggtc tgatgtgtgc tgttgctctc     3660

cttatcttaa ttttgctgat tgtttgcttc atcagaagaa acaagggtgg taaatatcca     3720

gttaaagaaa aggaagatgc ccatgctgac cctgaaatcc agcctatgaa ggaagatgat     3780

gggacatttg gagaatacag tgatgcagaa gaccacaagc ctttgaaaaa aggaagtcga     3840

actccttcag acaggactgt gaaaaaagaa gatagtgacg acagcctagt tgactatgga     3900

gaaggggtta atggccagtt caatgaggat ggctccttta ttggacaata cagtggtaag     3960

aaagagaaag agccggctga aggaaacgaa agctcagagg caccttctcc tgtcaacgcc     4020

atgaattcct ttgtttaatt tttaagctct ttgccaatat tccatttctc tagaatgttt     4080

atcctaagca cttgtttgtc agccctctca tactatgaac atatgggtag agagtatatt     4140

ttctgctgta tgttagtatt atgagaatag ttacagcaaa aacataactc agtcaaatga     4200

tatgttaata tgaactggaa tgcaaagtgc atactttttc attcaaaatg ggtattcttg     4260

atttcctcag aactgataaa aaataatgca acatcaccaa cagatcctgt tatttcctct     4320

gcaggataca gttcaatatg atgcatgaaa aatgctccac atttaaagga catacccgtg     4380

tatgttatga aaacatggtt tgatactttg tttatactac cctcagctga acccctatat     4440

atgaattccg ttttcattgt caagaatgtt actgtagtat tctctagaac ttcaatgtct     4500

ttgtggacat tgttgtgaaa ttggtgacta tgtatagctg tcgttagtct ttttgggaga     4560

ctgttaggaa cagtttgtac agtatatact tgctaaatga gttcattatg acagtcacat     4620

tgctgatgct tactgagaac tattacctac tcttggctcc tgttactccg taggcttctt     4680

aatcttccag gcattacagc agcacagtgt tctacttttt acatcatttc tatgttcggt     4740

tgtttttagg cataaacaat gtgtattgca gtgcatttcg gcatttgtgc catactgaaa     4800

gaatcaaaaa caaatcatcc aaattaaatt tcaaacatta tttcagagaa cacagggcaa     4860

gacacataca gtgccttcag atattaagca ttccacaaca tcgtgcattc tgtatcagct     4920

ggtccagtcc attctgggtc ctagattact gtcattgtct aaaagtaact tttaaaaagc     4980

agagttcatg aaaactgcaa tgctgggaaa agaaggaaac atgaaaataa aaataagaca     5040

gtttattaga aatagcattt cctcataagc ataaaaagaa aatctttgtt gccaactgaa     5100

gcacatgatg attttgtggt cctttatggt ttctattaca ttcagtaaga aagatgtcaa     5160

catgctagaa aattaatttt aaaactaagt tattccaaca ctaaaagcat acaacagcat     5220

gccaacagta atatattatt ctccaagact ttacctatgt aagtgttcaa aactctgcag     5280

cattaaacaa cgtgtatgca aattgttatg gatacatttc agaatctaag aaatcaggca     5340

agtgcttaaa aggccaacgg tccaagggat tacatctgca gtttaaaaag taaatatata     5400

ttctatcgta ttcataaaca atatctatca aatgggttac ctccaaatat gaaaatctat     5460

aacaacctat ggttgaagga atgctcagtt tcatttgcca ataaattggt ttctcataac     5520

ttgcatcaag tttaatttta agtaaagctt tttatatgta gatattttgt tgaatttgta     5580

aatacactta aaatgtagat gctatatgct tataggtgtt acatacaaat aaacatgcaa     5640

tgtttatgtt gtactgtata agaggtaagc taattaatgc agtgaatggg attggaaagc     5700

atctacttaa atatctattg ggttcccccc tccccccacc ttttttgctg tgaaactgaa     5760

atagtgaact tttctacgta ttgacagcag atttttcgat gaaatcttca gagctttgcc     5820

tatggggcac agtaggccta gtaacctggc atgtttgata tatgtaggta aagcataatt     5880

taaagtaatc ccaggtaaag atggccctaa atactttcat gtctctatat tcatttttca     5940

cagatccacc tgtctcttga aaatataaaa agacaaaaca ggtttgcctt ggcatcagag     6000

agcacaaaga ttaaaagtta ctttaaattt gccaatattt tgggagaaca ataaaactac     6060

attttttcct cttccatact ggtagatgcg aaatttatct gtgcatgaaa gggtcacttc     6120

tgtaatagtg caacagattt ggtattaaaa attaaatgtg gttttaaaag ttcctctctc     6180

ttttgtaatt tatgttccca attgagtgtg aatgtccaag taatggtgta tgtaatggta     6240

caggcaaatg tgactggatt tccctcaaaa aagtaactat taaacagtct tgatctcttt     6300

gtgactttta actttttcaa ac                                              6322


<210>  481
<211>  5827
<212>  DNA
<213>  homo sapiens

<400>  481
ggcgcgggtg cgggcgcccc agccggccgc gatcgcggga tttctgcgcc aggagatgag       60

gggcggtaga gccctggaat ggagatgtcc ttgacgcctg ggcagaggct gcagctgcag      120

gaccctgtgg ccactggaga taagtaatgg tgccatttga acacctactg gaaacggggc      180

aggaacagtg agtgacccca ggcgagcaca ggcaggtgcc aggagccagg atgcaaggat      240

gacgcctccg gaggccctgg cctcactccc acctgggcgc taggagccat cccggggctc      300

cagccaggag ccctgctgcc caggggcatg gccaaacctt tcttccgact ccagaagttt      360

ctccgccgaa cacagttcct gctgttcttc ctcacggctg cctacctgat gaccggcagc      420

ctgctgctgc tgcagcgggt ccgcgtggct ctcccacagg gcccccgggc acccggcccc      480

ctgcagacct tgccagtggc cgccgtggcg ctgggcgtgg gcttgctgga cagcagagcc      540

ctgcacgacc ctcgagtcag cccagagctg ctgctgggtg tggacatgct gcagagcccc      600

ctgacccggc cccggcccgg cccccgctgg ctccggagcc gcaactcgga gctgcgtcag      660

ttgcgtcgcc gctggttcca ccacttcatg agtgactccc agggaccgcc cgccctgggc      720

cccgaggctg ccaggcccgc catccacagc cgaggcacct acattggatg cttcagtgac      780

gatggccacg agaggactct gaaaggagct gtgttttatg acttgagaaa gatgactgtc      840

tcccactgcc aggatgcgtg tgctgagcgg tcctatgtct acgccggctt ggaggccggg      900

gcggagtgtt actgcgggaa ccggctgcca gcggtgagcg tggggctgga agagtgtaac      960

catgagtgca aaggcgagaa gggctctgtg tgcggggctg tggaccggct ctccgtgtac     1020

cgtgtggacg agctgcagcc gggctccagg aagcggcgga ccgccaccta ccgcggatgc     1080

ttccgactgc cagagaacat cacacatgcc ttccccagct ccctgataca ggccaatgtg     1140

accgtgggga cttgctcggg cttttgttcc cagaaagagt tccccttggc cattctcagg     1200

ggctgggaat gctactgtgc ttaccctacc ccccggttca acctgcggga tgccatggac     1260

agctcagtat gtggccagga ccctgaggca cagaggctgg cagaatactg tgaggtctac     1320

cagacacctg tgcaagacac tcgttgtaca gacaggaggt tcctgcctaa caaatccaaa     1380

gtgtttgtgg ctttgtcaag cttcccagga gccgggaaca catgggcacg gcacctcatt     1440

gagcatgcca ctggcttcta tacagggagc tactactttg atggaaccct ctacaacaaa     1500

gggttcaagg gcgaaaagga ccactggcgg agccgacgca ccatctgtgt caaaacccac     1560

gagagtggca ggagggagat tgagatgttt gattcagcca tcctgctaat ccggaaccca     1620

tacaggtccc tggtggcaga attcaacaga aaatgtgccg ggcacctggg atatgcagct     1680

gaccgcaact ggaagagcaa agagtggccg gactttgtca acagctacgc ctcgtggtgg     1740

tcctcgcacg tcctggactg gctcaagtac gggaagcggc tgctggtggt gcactacgag     1800

gagctgcggc gcagcctggt gcccacgtta cgggagatgg tggccttcct caacgtgtct     1860

gtgagcgagg agcggctgct ctgcgtggag aacaacaagg agggcagctt ccggcggcgc     1920

ggccggcgct cccacgaccc tgagcccttc accccggaga tgaaagactt gatcaatggc     1980

tacatccgga cggtggacca agccctgcgt gaccacaact ggacggggct gcccagggag     2040

tatgtgccca gatgataggc ctggcccacg ccgccgcccc cgctgagtga cgcaatcgca     2100

ccacggggct gcgctcccca ctctgatgct caggcccgtg gcctcactgg gacgaacggt     2160

gggtgggggg ctcaccctgg tgctgcctcc cgcacaagga gacctggaca caacagacac     2220

acatcacaag gcgaacacaa atggacacac atacctggcc acgaacccac acctcctcag     2280

acactcagac accactccag gctcatagcc ccgtcttgat gcagagaagc cacccacgtg     2340

gggtgtgcca ggcaccccca gatacaaatg cagccacgca cagacgtaac acacaggtgc     2400

caggccgtgt gctcctggag gctggctggc tgtctctctc acacagatac acgtgcgctc     2460

cctgggatcc gggaggccct gggcttcctg tgtgtagccc tggcatagac ttgctcgtca     2520

gggtgttcga ctctgggatg ctgggccggg cagacattta tgctctgagc agcaaggacc     2580

attgggatgg aggtgggcac aaagactgct gcttccaggg tgtgcggccc tggccgtgtg     2640

tctgacatcc cataaatgtg tgtgtggtgt gactacgggc accacaaact ccgcagcctt     2700

gcctctcttt tctctgtggc tgggctggct gcaccatggg cagggttgag gactgccccc     2760

caccccgccc aagccaatgc agacactgac ctcaagacca gccacaccaa gtctgtgcac     2820

tgcccaccac ccccttcaac ccctcctaca ccatgctccg gggcctgggg cctccttgcc     2880

tggcttcttc ctccagctat cctcagggaa gctggagatt caagtcatgc cccagaagca     2940

aggtgtaagc atgggggcgt ggggaagagg gcaggagctg aagttccagg ggagcccagg     3000

acccctgggg acctgtacac tagcaggatg ggtcttggga gttggcatgg ggagattgta     3060

agggctgtat ctccgcgatt actggtactg gtgctccacc cataggggcc ctgttctctc     3120

tggggtccca cactggggtc atgagagcta gttagtactc agcctgaccc ctaggtctgg     3180

tcctgccagc ctgggatggg ggtcaatgta tgctacacat cttgggctca caagtgaggc     3240

tgtggaggcc aggaggttca agtatggagg gtaggagtgc aacccaggag caacgctcaa     3300

ggtggccgag atgcagggag gattgtggcg atccggttgc acactggcct ctgtggaggt     3360

cagggaggtg ggaaggtggg tgggcctgaa ctcaggcagc ccttcagtgg cttcttcagg     3420

cctaggataa ccctggccag gccccatggt cctgctctgg gtcagctgtc agggagacct     3480

cccttcagcc tgagccaagc tgcattggga ggagaaggca gggtgaggga tctgggagag     3540

caggacgttg agatatcctg accctctgct tcctagcctg atgatgggga acccagagcc     3600

acccgctatg agcacaggcc gggggtggaa ggcccagtag agctgccctt ccccagatgg     3660

aagcttcctc caaccttcag tttggccagt gggtgggttt gggcatctgt gcccctggtg     3720

gcctccaaat ccttcctggg attcccccaa acccacactg atgcgaagct gttcttgacc     3780

ctcccatagc atcaactcag ttcagctcaa agctagaaac accaaggtct ttgaaaatgt     3840

ttattggctc aggatagctt cggcatccaa tctgcgaagg cccctgatgg agctatttct     3900

tcctagtatc aggagcaatt gagacccctc aggagtttcc acactgctgt ggacgggata     3960

gccagggcag acctgcatcc cagagcaagc ctagatcctt gaaagcaatg tcaggcgtgg     4020

cagtggggaa gccatggagg ctgggaaggg caaagtgtgg agagaggagt gaccgggact     4080

ggagccaggg tctggggaga gcaacagcac caggcttttc ctggtagttg gattggtaca     4140

ttcactgctg ccaggtaccc agagatgtca tctctctcca ggtagagcat caccagctcc     4200

tgtggccttg tagatgactc tgtacctcag tgaagagtgc aggcaagtag agtgatgggg     4260

tcagtgtcca tccagtttac gctgagtcag tccatacagc aagacacctg gcacttggca     4320

ggtactcctg gatgttgatg agcaaggaag agcaacggcc ctgtcagctg gcagtggtcc     4380

tcacagcctt catcccaggt ctgcctacgt gggagatctc atcagaaaca ggaacgggga     4440

tctgtctgtg cttgcaggaa agtccatttg tttttctcca agttaggtct catctacagc     4500

tcttagcttc tcagtaaaga ggatactctc ccaaccagcc aaggaataaa agctgatctg     4560

tatgtagggc agaagtgtgg caaatgcatc aggaaccggt tagaacagaa cagagaaacc     4620

ctgactgtct acagattcca actttaatag caagcctgtg gagttacaca aacctgtgtt     4680

aaaacatgta atttttatgg atttcatctc ccgttgtgga tcaatttgga aaaaccaaaa     4740

tatgtaattt taaaaaacta aaacacatcc tggtagtccc agtgatgtgt aaatgagaga     4800

gaagaataga caggcttcca aaccctggga agaaagctgc ttaattatgt gaacatctta     4860

taatgaagtc tcttgcagct aaaattagat tttgagtgca tgaatctgtg ataatgtttg     4920

catatcagaa tgcattctcc ccttaaaagt agcagtagcc acttggttct tagggggccc     4980

caagaggaga ggagaagtgc tgaggttgat gttacgactg caagaattct tgggacacag     5040

gtttgttttc tgctgacttg ctcggaaacc cattggaggt atctgaaatg tgatgactcc     5100

aaaggggttc atttcactat agggagaaat tgattcgtct gacttcctat ttatcaccac     5160

tcaatattgg gtgagttggt ctgaacaagg tggggataaa gtagagtgga aataatgtag     5220

agtcgtcaga ctgaaaggcc aggttgtagt cccagctctt atctgccatc ttggacaaag     5280

cttttcccat ctccagtctc agtttcccat ccataaaatg ggggaagtgg taggtcttgc     5340

tgattgcatc cacattcatt cctccatttc ctttcccagc aaccccccat ttctgtttgg     5400

gaattcatat gatctgccag agcctctcca ggggtggaat acatgtcctg gactaagcca     5460

atgacacctt ccatctttcc agctatggtg actgggttag gtatgatctt gtgagttaag     5520

acaatgaagc cagagggaat ttcaagactt atgggaatgc tgggtagaag ctgttttaat     5580

tcccctgttg aatgtgaaaa aggtagtagt attcctgggt ctttatgatg accaccttgg     5640

gccttgggat catgaccagg aatcacgtga agctgacacc actgaaggga gagttgagag     5700

gcagaaagag atcaagtcct tggtgaaatt gtttaagtac aggatcaagc cttgcttgag     5760

attggcctta cctctggact ttttttgtta tatgagctaa taaattctgt ttattgttta     5820

aaaaaaa                                                               5827


<210>  482
<211>  5946
<212>  DNA
<213>  homo sapiens

<400>  482
tttttttttt ttttttgctt aaaaaaaagc catgacggct ctcccacaat tcatcttccc       60

tgcgccatct ttgtattatt tctaatttat tttggatgtc aaaaggcact gatgaagata      120

ttttctctgg agtctccttc tttctaaccc ggctctcccg atgtgaaccg agccgtcgtc      180

cgcccgccgc cgccgccgcc gccgccgccg cccgccccgc agcccaccat gtctcgccgc      240

aagcaaggca aaccccagca cttaagcaaa cgggaattct cgcccgagcc tcttgaagcc      300

attcttacag atgatgaacc agaccacggc ccgttgggag ctccagaagg ggatcatgac      360

ctcctcacct gtgggcagtg ccagatgaac ttcccattgg gggacattct tatttttatc      420

gagcacaaac ggaaacaatg caatggcagc ctctgcttag aaaaagctgt ggataagcca      480

ccttcccctt caccaatcga gatgaaaaaa gcatccaatc ccgtggaggt tggcatccag      540

gtcacgccag aggatgacga ttgtttatca acgtcatcta gaggaatttg ccccaaacag      600

gaacacatag cagataaact tctgcactgg aggggcctct cctcccctcg ttctgcacat      660

ggagctctaa tccccacgcc tgggatgagt gcagaatatg ccccgcaggg tatttgtaaa      720

gatgagccca gcagctacac atgtacaact tgcaaacagc cattcaccag tgcatggttt      780

ctcttgcaac acgcacagaa cactcatgga ttaagaatct acttagaaag cgaacacgga      840

agtcccctga ccccgcgggt tggtatccct tcaggactag gtgcagaatg tccttcccag      900

ccacctctcc atgggattca tattgcagac aataacccct ttaacctgct aagaatacca      960

ggatcagtat cgagagaggc ttccggcctg gcagaagggc gctttccacc cactcccccc     1020

ctgtttagtc caccaccgag acatcacttg gacccccacc gcatagagcg cctgggggcg     1080

gaagagatgg ccctggccac ccatcacccg agtgcctttg acagggtgct gcggttgaat     1140

ccaatggcta tggagcctcc cgccatggat ttctctagga gacttagaga gctggcaggg     1200

aacacgtcta gcccaccgct gtccccaggc cggcccagcc ctatgcaaag gttactgcaa     1260

ccattccagc caggtagcaa gccgcccttc ctggcgacgc cccccctccc tcctctgcaa     1320

tccgcccctc ctccctccca gcccccggtc aagtccaagt catgcgagtt ctgcggcaag     1380

acgttcaaat ttcagagcaa cctggtggtg caccggcgca gccacacggg cgagaagccc     1440

tacaagtgca acctgtgcga ccacgcgtgc acccaggcca gcaagctgaa gcgccacatg     1500

aagacgcaca tgcacaaatc gtcccccatg acggtcaagt ccgacgacgg tctctccacc     1560

gccagctccc cggaacccgg caccagcgac ttggtgggca gcgccagcag cgcgctcaag     1620

tccgtggtgg ccaagttcaa gagcgagaac gaccccaacc tgatcccgga gaacggggac     1680

gaggaggaag aggaggacga cgaggaagag gaagaagagg aggaagagga ggaggaggag     1740

ctgacggaga gcgagagggt ggactacggc ttcgggctga gcctggaggc ggcgcgccac     1800

cacgagaaca gctcgcgggg cgcggtcgtg ggcgtgggcg acgagagccg cgccctgccc     1860

gacgtcatgc agggcatggt gctcagctcc atgcagcact tcagcgaggc cttccaccag     1920

gtcctgggcg agaagcataa gcgcggccac ctggccgagg ccgagggcca cagggacact     1980

tgcgacgaag actcggtggc cggcgagtcg gaccgcatag acgatggcac tgttaatggc     2040

cgcggctgct ccccgggcga gtcggcctcg gggggcctgt ccaaaaagct gctgctgggc     2100

agccccagct cgctgagccc cttctctaag cgcatcaagc tcgagaagga gttcgacctg     2160

cccccggccg cgatgcccaa cacggagaac gtgtactcgc agtggctcgc cggctacgcg     2220

gcctccaggc agctcaaaga tcccttcctt agcttcggag actccagaca atcgcctttt     2280

gcctcctcgt cggagcactc ctcggagaac gggagtttgc gcttctccac accgcccggg     2340

gagctggacg gagggatctc ggggcgcagc ggcacgggaa gtggagggag cacgccccat     2400

attagtggtc cgggcccggg caggcccagc tcaaaagagg gcagacgcag cgacacttgt     2460

gagtactgtg ggaaagtctt caagaactgt agcaatctca ctgtccacag gagaagccac     2520

acgggcgaaa ggccttataa atgcgagctg tgcaactatg cctgtgccca gagtagcaag     2580

ctcaccaggc acatgaaaac gcatggccag gtggggaagg acgtttacaa atgtgaaatt     2640

tgtaagatgc cttttagcgt gtacagtacc ctggagaaac acatgaaaaa atggcacagt     2700

gatcgagtgt tgaataatga tataaaaact gaatagaggt atattaatac ccctccctca     2760

ctcccacctg acaccccctt tttcaccact ccccttcccc atcgccctcc agccccactc     2820

cctgtaggat ttttttctag tcccatgtga tttaaacaaa caaacaaaca aacagaagta     2880

acgaagctaa gaatatgaga gtgcttgtca ccagcacacc tgtttttttt ctttttcttt     2940

ttcttttttc tttttccttt tttttttttt tcctttatgt tctcaccgtt tgaatgcatg     3000

atctgtatgg ggcaatacta ttgcatttta cgcaaacttt gagcctttct cttgtgcaat     3060

aatttacatg ttgtgtatgt ttttttttaa acttagacag catgtatggt atgttatggc     3120

tattttaaat tgtccctaat tcgttgctga gcaaacatgt tgctgtttcc agttccgttc     3180

tgagagaaaa agagagagag agagaaaaag accatgctgc atacattctg taatacatat     3240

catgtacagt tttattttat aacgtgagga ggaaaaacag tctttggatt aaccctctat     3300

agacagaata gatagcactg aaaaaaaatc tctatgagct aaatgtctgt ctctaaaggg     3360

ttaaatgtat caattggaaa ggaagaaaaa aggccttgaa ttgacaaatt aacagaaaaa     3420

cagaacaagt ttattctatc atttggtttt aaaatatgag tgccttggat ctattaaaac     3480

cacatcgatg gttctttcta cttgttataa acttgtagct taattcagca ttgggtgagg     3540

taataaacct taggaactag catataattc tatattgtat ttctcacaac aatggctacc     3600

taaaaagatg acccattatg tcctagttaa tcatcatttt tcctttagtt taattttata     3660

aacaaaactg attataccag tataaaagct actttgctcc tggtgagagc ttaaaagaaa     3720

tgggctgttt tgcccaaagt tttatttttt ttaaacaatg attaaattga atgtgtaatg     3780

tgcaaaagcc ctggaacgca attaaataca ctagtaagga gttcatttta tgaagatatt     3840

tgctttaata atgtcttttt aaaaatactg gcaccaaaag aaatagatcc agatctactt     3900

ggttgtcaag tggacaatca aatgataaac tttaagacct tgtataccat attgaaagga     3960

agaggctgac aataaggttt gacagagggg aacagaagaa aataatatga tttattagca     4020

caacgtggta ctatttgcca tttaaaacta gaacaggtat ataagctaat attgatacaa     4080

tgatgattaa ctatgaattc ttaagacttg catttaaatg tgacattctt aaaaaaagaa     4140

gagaaagaat tttaagagta gcagtatata tgtctgtgct ccctaaaagt tgtacttcat     4200

ttcttttcca tacactgtgt gctatttgtg ttaacatgga agaggattca ttgtttttat     4260

ttttattttt ttaatttttt cttttttatt aagctagcat ctgccccagt tggtgttcaa     4320

atagcacttg actctgcctg tgatatctgt atcttttctc taatcagaga tacagaggtt     4380

gagtataaaa taaacctgct cagataggac aattaagtgc actgtacaat tttcccagtt     4440

tacaggtcta tacttaaggg aaaagttgca agaatgctga aaaaaaattg aacacaatct     4500

cattgaggag cattttttaa aaactaaaaa aaaaaaaact ttgccagcca tttacttgac     4560

tattgagctt acttacttgg acgcaacatt gcaagcgctg tgaatggaaa cagaatacac     4620

ttaacataga aatgaatgat tgctttcgct tctacagtgc aaggattttt ttgtacaaaa     4680

cttttttaaa tataaatgtt aagaaaaatt ttttttaaaa aacacttcat tatgtttagg     4740

ggggaactgc attttagggt tccattgtct tggtggtgtt acaagacttg ttatccattt     4800

aaaaatggta gtggaaattc tatgccttgg atacacaccg ctcttcaggt tgtaaaaaaa     4860

aaaaacatac attggggaaa ggtttaagat tatatagtac ttaaatatag gaaaatgcac     4920

actcatgttg attcctatgc taaaatacat ttatggtctt ttttctgtat ttctagaatg     4980

gtatttgaat taaatgttca tctagtgtta ggcactatag tatttatatt gaagcttgta     5040

tttttaactg ttgcttgttc tcttaaaagg tatcaatgta ccttttttgg tagtggaaaa     5100

aaaaaagaca ggctgccaca gtatattttt ttaatttggc aggataatat agtgcaaatt     5160

atttgtatgc ttcaaaaaaa aaaaaaagag agaaacaaaa aagtgtgaca ttacagatga     5220

gaagccatat aatggcggtt tgggggagcc tgctagaatg tcacatggat ggctgtcata     5280

ggggttgtac atatcctttt ttgttccttt ttcctgctgc catactgtat gcagtactgc     5340

aagctaataa cgttggtttg ttatgtagtg tgctttttgt ccctttcctt ctatcaccct     5400

acattccagc atcttacctt catatgcagt aaaagaaaga aagaaaaaaa aaggaaaaaa     5460

aaaaaaaaac caatgttttg cagttttttt cattgccaaa aactaaatgg tgctttatat     5520

ttagattgga aagaatttca tatgcaaagc atattaaaga gaaagcccgc tttagtcaat     5580

acttttttgt aaatggcaat gcagaatatt ttgttattgg ccttttctat tcctgtaatg     5640

aaagctgttt gtcgtaactt gaaattttat cttttactat gggagtcact atttattatt     5700

gcttatgtgc cctgttcaaa acagaggcac ttaatttgat cttttatttt tctttgtttt     5760

tatttttttt tttatttaga tgaccaaagg tcattacaac ctggcttttt attgtatttg     5820

tttctggtct ttgttaagtt ctattggaaa aaccactgtc tgtgtttttt tggcagttgt     5880

ctgcattaac ctgttcatac acccattttg tccctttatt gaaaaaataa aaaaaattaa     5940

agtaca                                                                5946


<210>  483
<211>  977
<212>  DNA
<213>  homo sapiens

<400>  483
gggctccgcg cccggccagc ctgaggtggg gtcggtgccc ccggcggcac ggcgctgggg       60

aggcgatggc gccggccgcg tccaggctgc gggccgaagc cgggctcggg gcgctgccgc      120

ggcgggcgct cgcccagtac ctgctcttcc tgcggctcta cccggtgctc accaaggcgg      180

ccaccagtgg cattttgtca gcacttggga acttcctggc ccagatgatt gagaagaagc      240

ggaaaaaaga aaactctaga agtctggatg tcggtgggcc tctgagatat gccgtttacg      300

ggttcttctt cacagggccg ctgagtcact tcttctactt cttcatggaa cattggatcc      360

ctcctgaggt ccccctggca gggctcagga ggcttctcct ggaccgcctc gtctttgcac      420

cggccttcct catgttgttc ttcctcatca tgaactttct ggaggggaaa gacgcctcag      480

ccttcgccgc caagatgagg gggggcttct ggccggcgct gaggatgaac tggcgggtgt      540

ggacgccact acagttcatc aacatcaact acgtccctct gaagttccgg gtgctcttcg      600

ccaacctggc agctctgttc tggtatgcct acctggcctc cttggggaag tgacgaccgc      660

tgggagaaca tcaggtgcac tgtggacgtg ggtctggggg tctcacccgc ccagcgagag      720

cagaaccaat ccagtcagga tgtcactgac tctaaatcag gtgattcaag atgcccaaaa      780

atgatggata gagaaacaga aatctctgaa tgtcagaacc ctgtctttta aaaaggcagt      840

cgctgccttc aggtggtgct gccccagaaa cttaaaattt agtcgaggca gtttcaattg      900

ttactgtgga ccgaattagg atcacaataa acgataatgc aggttcttca atggtgaaaa      960

aaaaaaaaaa aaaaaaa                                                     977


<210>  484
<211>  1752
<212>  DNA
<213>  homo sapiens

<400>  484
agggcgcagc aggccaaggg ggaggtgcga gcgtggacct gggacgggtc tgggcggctc       60

tcggtggttg gcacgggttc gcacacccat tcaagcggca ggacgcactt gtcttagcag      120

ttctcgctga ccgcgctagc tgcggcttct acgctccggc actctgagtt catcagcaaa      180

cgccctggcg tctgtcctca ccatgcctag cctttgggac cgcttctcgt cgtcgtccac      240

ctcctcttcg ccctcgtcct tgccccgaac tcccacccca gatcggccgc cgcgctcagc      300

ctgggggtcg gcgacccggg aggaggggtt tgaccgctcc acgagcctgg agagctcgga      360

ctgcgagtcc ctggacagca gcaacagtgg cttcgggccg gaggaagaca cggcttacct      420

ggatggggtg tcgttgcccg acttcgagct gctcagtgac cctgaggatg aacacttgtg      480

tgccaacctg atgcagctgc tgcaggagag cctggcccag gcgcggctgg gctctcgacg      540

ccctgcgcgc ctgctgatgc ctagccagtt ggtaagccag gtgggcaaag aactactgcg      600

cctggcctac agcgagccgt gcggcctgcg gggggcgctg ctggacgtct gcgtggagca      660

gggcaagagc tgccacagcg tgggccagct ggcactcgac cccagcctgg tgcccacctt      720

ccagctgacc ctcgtgctgc gcctggactc acgactctgg cccaagatcc aggggctgtt      780

tagctccgcc aactctccct tcctccctgg cttcagccag tccctgacgc tgagcactgg      840

cttccgagtc atcaagaaga agctgtacag ctcggaacag ctgctcattg aggagtgttg      900

aacttcaacc tgagggggcc gacagtgccc tccaagacag agacgactga acttttgggg      960

tggagactag aggcaggagc tgagggactg attcctgtgg ttggaaaact gaggcagcca     1020

cctaaggtgg aggtggggga atagtgtttc ccaggaagct cattgagttg tgtgcgggtg     1080

gctgtgcatt ggggacacat acccctcagt actgtagcat gaaacaaagg cttaggggcc     1140

aacaaggctt ccagctggat gtgtgtgtag catgtacctt attatttttg ttactgacag     1200

ttaacagtgg tgtgacatcc agagagcagc tgggctgctc ccgccccagc ccggcccagg     1260

gtgaaggaag aggcacgtgc tcctcagagc agccggaggg aggggggagg tcggaggtcg     1320

tggaggtggt ttgtgtatct tactggtctg aagggaccaa gtgtgtttgt tgtttgtttt     1380

gtatcttgtt tttctgatcg gagcatcact actgacctgt tgtaggcagc tatcttacag     1440

acgcatgaat gtaagagtag gaaggggtgg gtgtcaggga tcacttggga tctttgacac     1500

ttgaaaaatt acacctggca gctgcgttta agccttcccc catcgtgtac tgcagagttg     1560

agctggcagg ggaggggctg agagggtggg ggctggaacc cctccccggg aggagtgcca     1620

tctgggtctt ccatctagaa ctgtttacat gaagataaga tactcactgt tcatgaatac     1680

acttgatgtt caagtattaa gacctatgca atatttttta cttttctaat aaacatgttt     1740

gttaaaacag tt                                                         1752


<210>  485
<211>  7735
<212>  DNA
<213>  homo sapiens

<400>  485
ctctctcccg gcgaagctgg gaattgggtg ggattacacg gagcagcccc gccgccgccg       60

ctggcagagg ccggcttgga gagggcgggg gttcccctcc gtcagtcgcc cctggcgccc      120

ctcgcctcgt cgcactctcc gcctcgctct ccccgacgtc cggccaggag gagccggtag      180

catcgggagc ctcgcgccga gggcgccgcg gtccgcgccc cgcgactgca gcccccggcc      240

tggccccggc ggggcgcccc ctcccctccc cctcctgcga gctgggatcc ggccggcttc      300

cgccctcccc tggccgcgag accggccccg gcggctgggc cgccagtagc tccagccatg      360

ggctcggggc gcgtacccgg gctctgcctg cttgtcctgc tggtccacgc ccgcgccgcc      420

cagtacagca aagccgcgca agatgtggat gagtgtgtgg aggggactga caactgccac      480

atcgatgcta tctgccagaa caccccgagg tcatacaagt gcatctgcaa gtctggctac      540

acaggggacg gcaaacactg caaagacgtg gatgagtgcg agcgagagga taatgcaggt      600

tgtgtgcatg actgtgtcaa catccctggc aattaccggt gtacctgcta tgatggattc      660

cacctggcac atgacggaca caactgtctg gatgtggacg agtgtgccga gggcaacggc      720

ggctgtcagc agagctgtgt caacatgatg ggcagctatg agtgccactg ccgggaaggc      780

ttcttcctca gcgacaacca gcatacctgt atccagcggc cagaagaagg aatgaattgc      840

atgaacaaga accacggctg tgcccacatt tgccgggaga cacccaaggg gggtattgcc      900

tgtgaatgcc gtcctggctt tgagcttacc aagaaccaac gggactgtaa attgacatgc      960

aactatggta acggcggctg ccagcacacg tgtgatgaca cagagcaggg tccccggtgc     1020

ggctgccata tcaagtttgt gctccatacc gacgggaaga catgcatcga gacctgtgct     1080

gtcaacaacg ggggctgtga cagtaagtgc catgatgcag cgactggtgt ccactgcacc     1140

tgccctgtgg gcttcatgct gcagccagac aggaagacgt gcaaagatat agatgagtgc     1200

cgcttaaaca acgggggctg tgaccatatt tgccgcaaca cagtgggcag cttcgaatgc     1260

agttgcaaga aaggctataa gcttctcatc aatgagagga actgccagga tatagacgag     1320

tgttcctttg atcgaacctg tgaccacata tgtgtcaaca caccaggaag cttccagtgt     1380

ctctgccatc gtggctacct gttgtatggt atcacccact gtggggatgt ggatgaatgc     1440

agcatcaacc ggggaggttg ccgctttggc tgcatcaaca ctcctggcag ctaccagtgt     1500

acctgcccag caggccaggg tcggctgcac tggaatggca aagattgcac agagccactg     1560

aagtgtcagg gcagtcctgg ggcctcgaaa gccatgctca gctgcaaccg gtctggcaag     1620

aaggacacct gtgccctgac ctgtccctcc agggcccgat ttttgccaga gtctgagaat     1680

ggcttcacgg tgagctgtgg gacccccagc cccagggctg ctccagcccg agctggccac     1740

aatgggaaca gcaccaactc caaccactgc catgaggctg cagtgctgtc cattaaacaa     1800

cgggcctcct tcaagatcaa ggatgccaaa tgccgtttgc acctgcgaaa caaaggcaaa     1860

acagaggagg ctggcagaat cacagggcca ggtggtgccc cctgctctga atgccaggtc     1920

accttcatcc accttaagtg tgactcctct cggaagggca agggccgacg ggcccggacc     1980

cctccaggca aagaggtcac aaggctcacc ctggaactgg aggcagaggt cagagccgaa     2040

gaaaccacag ccagctgtgg gctgccctgc ctccgacagc gaatggaacg gcggctgaaa     2100

ggatccctga agatgctcag aaagtccatc aaccaggacc gcttcctgct gcgcctggca     2160

ggccttgatt atgagctggc ccacaagccg ggcctggtag ccggggagcg agcagagccg     2220

atggagtcct gtaggcccgg gcagcaccgt gctgggacca agtgtgtcag ctgcccgcag     2280

ggaacgtatt accacggcca gacggagcag tgtgtgccat gcccagcggg caccttccag     2340

gagagagaag ggcagctctc ctgcgacctt tgccctggga gtgatgccca cgggcctctt     2400

ggagccacca acgtcaccac gtgtgcaggt cagtgcccac ctggccaaca ctctgtagat     2460

gggttcaagc cctgtcagcc atgcccacgt ggcacctacc aacctgaagc aggacggacc     2520

ctatgcttcc cttgtggtgg gggcctcacc accaagcatg aaggggccat ttccttccaa     2580

gactgtgaca ccaaagtcca gtgctcccca gggcactact acaacaccag catccaccgc     2640

tgtattcgct gtgccatggg ctcctatcag cccgacttcc gtcagaactt ctgcagccgc     2700

tgtccaggaa acacaagcac agactttgat ggctctacca gtgtggccca atgcaagaat     2760

cgtcagtgtg gtggggagct gggtgagttc actggctata ttgagtcccc caactacccg     2820

ggcaactacc cagctggtgt ggagtgcatc tggaacatca accccccacc caagcgcaag     2880

atccttatcg tggtaccaga gatcttcctg ccatctgagg atgagtgtgg ggacgtcctc     2940

gtcatgagaa agaactcatc cccatcctcc attaccactt atgagacctg ccagacctac     3000

gagcgtccca ttgccttcac tgcccgttcc aggaagctct ggatcaactt caagacaagc     3060

gaggccaaca gcgcccgtgg cttccagatt ccctatgtta cctatgatga ggactatgag     3120

cagctggtag aagacattgt gcgagatggc cggctctatg cctctgaaaa ccaccaggag     3180

attttaaagg acaagaagct catcaaggcc ttctttgagg tgctagccca cccccagaac     3240

tacttcaagt acacagagaa acacaaggag atgctgccaa aatccttcat caagctgctc     3300

cgctccaaag tttccagctt cctgaggccc tacaaatagt aaccctaggc tcagagaccc     3360

aattttttaa gcccccagac tccttagccc tcagagccgg cagcccccta ccctcagaca     3420

aggaactctc tcctctcttt ttggagggaa aaaaaaaata tcactacaca aaccaggcac     3480

tctccctttc tgtctttcta gtttcctttc cttgtctctc tctgcctgcc tctctactgt     3540

tccccctttt ctaacacact acctagaaaa gccattcagt actggctcta gtccccgtga     3600

gatgtaaaga aacagtacag ccccttccac tgcccatttt accagctcac attcccgacc     3660

ccatcagctt ggaagggtgc tagaggccca tcaaggaagt gggtctggtg ggaaacgggg     3720

aggggaaaga agggcttctg ccattatagg gttgtgcctt gctagtcagg ggccaaaatg     3780

tcccctggct ctgctcccta gggtgattct aacagcccag ggtcctgcca aagaagcctt     3840

tgatttacag gcttaatgcc agcaccagtc ctctggggca catggtttga gctctggact     3900

tcccacatgg ccagctttct tgtctataca gatcctctct ttctttccct acgtctgcct     3960

ggggtctact ccataagggt ttacaaatgg cccacaacac tgagttagtg gacaccggct     4020

aaatgaggaa gagcagcagg cattgtcatg gtgaatgccc cgctgtagct ccctgagaga     4080

aagactgtaa ctctgcagga cagaaacaag gttttaaagc attgccaaaa aaaagaaaac     4140

agaaagaaaa aatgtatcat ctaaaggact agacacagaa caattggaag tcaacttcaa     4200

acactaatcc cttttcttgt cttccctggc ccagccacct cctcagcccc atgtgatgct     4260

ccctggggga gccctactcc ccttgctaca tgttgtcctt aaacatggtt attgacctga     4320

agccagccta ggccttgccc tacagttgtt tttcccttgt agccccagct ggcttgtggg     4380

cttcaccaaa gaggacccca ctctgaagcc agcctggagc cacctacctc tggcctcagg     4440

ctgtgggcag caaaaggaat gtgtgtgcac ttggcgagcc tcctgcccac cctgtccaca     4500

cctaataagt gcaatcattt tgagtctttc tatgttgtct agacggaggg gtttttgttt     4560

tctgggtttg ttttttgttt ttgtttcttc ttcctctatt agcaaaaccc tatttatagc     4620

tgcccaagag aaaagagtgt atgtttggag tggaagaaaa tcggttttga atctcatgaa     4680

ccttgagtgc tggagcatct gatctgtctc tatgccacca ctggccacct agagcccttg     4740

gctgtggtaa tccagggtaa ttgcgcagag gcatctgatg tgtaggaaag taattctggg     4800

gatttgatgg agcagaaagg agagagacct atgtttgcta aaccaatctt gctatcccta     4860

tgcctctcca tggagtcagt gtggacctca tgattataga ggccaatgga actggtcagt     4920

gattctctac cccaagtagg gaaaacctcc atcttttccc tgtcttcatc ctgttatccc     4980

ctggtgtaca catggaagag gaccaggaca taccacctgg ggatgggctg actcagggtc     5040

ccgaggccag agacaaagct gtgggagcca agaataagac agaaggcatc agatatttgc     5100

ctggctctgg tcacttccct ttgaagttga cttcaagctt agcttcctca actactgttt     5160

ttcagaagga agaaagaatc aaatggaaga agaatcaagt ccatgcccaa gcccaaagcc     5220

tgcacacatt ctgcccttaa tccaagtgtt gcctataaaa ttattttctg ttttctcact     5280

ctagttcccc caaagctgta gtcccaatca atcaaaggct accaactgag tcctcaggtt     5340

catttctttt tttttttttt ttctttttaa ctctcctggt aactcacaga acagctcagg     5400

ttcatttcta ggtgactgtc ctaggctact gctcccccag gagactcaac actaaataaa     5460

ggagtctgac tccctgccct cccatcagta gcattcatca gccaaaacgg ccatagcagt     5520

aggtagccaa tgacacagct agattccctg acaaccatta gccaacatca tggtccttgt     5580

gggtagagtg tctggctacc tttgtctttc tgggtcaagg agggccactg taaagatgca     5640

aaatggctgc ttccaaacaa gggaaatggt catttagtat gagtgtctct gtacttccca     5700

ggaagcacca tgaaaactgc tttaatcaac tctgactatc ctaattctcc accagaagct     5760

aggataactt tctttctttc tttctttttt tttttttttt tttttgagat ggagtctcgc     5820

tctgtcaccc aggctggagt gtaatggtgc tatctcggcc tactgcaacc tccgcctccc     5880

aggctcaagc aattctgcct cggcctccca agtagctggg attacaggca tgcgccaccg     5940

cgcccagcta atttttgtat ttttagtaga gatggggttt caccatgttg cccgggctgg     6000

tcttgaactc ttgacctcag gtgatccacc cgcctcagtc tcccaaagtg ctgggattac     6060

aggcatgagc caccgcgccc agcctaggat aactttctga ttcctctctg ccagccgttt     6120

tgcgtctctt ggaaagccaa acggtgacca tgcttcttaa tttatgcctt cagggtctgg     6180

cttctccttt ctcccttcct ttcctgtcac accatgcata catacataca aatacacatc     6240

cttcaaccat ttattccatg gcttatgaga cctgcaaatg agttccacag tacggaaggc     6300

atagaccact aggcttctta attgatgtca aggcagatct tggtgagcag gtaaaaacct     6360

gctattgtcc accaagttta atttaggtcc tccaagttgg agggttaaga acccaggcaa     6420

agctgctgct gaatctatgg aggaggctgg ccctgggaca tcaaactagg ggttaactgg     6480

attgaatgag gagtcaacgc tcagggacat tctaggtctt tacaggtcag acagaagaga     6540

ggtttttacc attggaggga aatggaaaga tggtataaat aggatccctt catgaagcaa     6600

cccagaggcc tctctgcagc gtgtagggtg tggggcgaca gtattgtggg gcttccattc     6660

atcttagtac aaaacctcac ctgctctgag cctggaaatg ggagggcttc acgcaccaag     6720

taatgcacac cagaaaggca cttatatcct cagcaacatg gcagttcctc tttacttctc     6780

tgcctccctc tttctatatt atcaggccat gcctattcct acaacctgag acaactcttg     6840

gagtcagaag aaaactgacc agatcctgga tctgagctgc ctgctccagg cctagaaatc     6900

cccaaaggct ggcactgagc tgtgactgct ttaacagccc ccaagatttg gtcagtttga     6960

ggtggtggag actcagattt gttgctgaaa gttcagtaac acagtcctgg tctttggccc     7020

tagagaaact ttttatatga gaagtgttct ctatatacat gtttgaggtg actctggaat     7080

ggattatgag gtcatatctc aaaatgtcag aaaacgttat agagcactcg aacttttgta     7140

tttgctgctt aacctcaata ttacagccac aaacaagggg taccaagaca aagtataact     7200

gagcataagc agaaaatgtt aaccctccag gtttctttct taagcacaat aaaagtggga     7260

gcgaacaaca caaggatatt tttacatttg acccgtctca aaagtagcac accctatcct     7320

tgtgccatta tttgtacaag gaaatatatg attagaagga atagaacccc cagttgtcat     7380

cagctttttt agacaccaca ggttgtagca gtttgaacaa actgaaaact ttatacttct     7440

gtgtgagctg aactcaagtt tcagaataat catcgccatg tgggaggctt tttgttaaat     7500

gcagaagaaa tttcaaaata ttgtatttat atctgccttc cactgctgcc aatttagtaa     7560

gcatctccta tacaatcgac aataaacagc aaatgatgca gttcatagag tattttgcac     7620

ttggggaaaa atatgtatct gaattgtaaa aagaaatgtt tggattttgt atgtcttttt     7680

tattattatt aaaatactaa atgaaactcc tcaaaaaaaa aaaaaaaaaa aaaaa          7735


<210>  486
<211>  5782
<212>  DNA
<213>  homo sapiens

<400>  486
agttgccctg tcagtgcagg tggaggcccc ggcggggcaa agtggcagga acctcttaaa       60

gggcgagagc ggcgcggagc cagaacgcgg tcggcccggt ccccgccgca cccagcccag      120

agaagagttt agtgactgag gccgaaaatt cacagcacca acagaaggaa gagggtgagg      180

aagccataaa ctcaggccaa caagaacctc agcaggagga atcttgtcaa acagcagctg      240

aaggagataa ttggtgtgaa cagaagctga aagcttctaa tggagacact cctacacatg      300

aagacttgac caagaacaag gagcggacat cagaaagcag aggactttca cgactattct      360

cctcgtttct caaaaggccc aaatctcagg tgtccgagga agaaggcaaa gaagtagagt      420

cagataaaga aaaaggtgaa ggaggtcaga aagagataga atttggaacc agtcttgatg      480

aagagatcat tttaaaggcc ccaattgcag ctcctgaacc ggaactcaaa acagacccat      540

ctttggatct tcattcatta agcagtgcag aaacacagcc tgctcaggaa gaactcagag      600

aagatccaga ttttgaaatt aaggaaggag aaggacttga agagtgctcc aaaatagaag      660

taaaagaaga aagccctcaa tcaaaagcag aaacagaatt aaaagcttcc caaaaaccaa      720

tcagaaaaca caggaacatg cactgcaagg tttctttgtt ggatgacaca gtttatgaat      780

gtgttgtgga gaaacatgct aagggacaag atttgcttaa acgagtatgt gagcatctca      840

atcttttgga agaagactat tttggtctag ccatttggga taacgcaacc tctaagacat      900

ggctggattc cgccaaagaa ataaaaaagc aggttcgtgg tgtcccttgg aattttacat      960

ttaatgtaaa gttttatcca cctgacccag cacagttaac agaagacata acaagatatt     1020

atttatgtct tcagcttcgg caggacatag ttgcaggacg tctgccctgt tcctttgcaa     1080

ccttagcatt attaggttct tacaccatcc agtctgaact gggagactac gacccagaac     1140

tccatggcgt ggattatgtt agtgatttta aactggcccc gaatcagacc aaggaacttg     1200

aagagaaggt catggaactg cataagtcat acaggtccat gactccagct caggctgact     1260

tggagtttct tgagaatgcc aaaaagttgt ctatgtatgg agttgatctt cataaagcaa     1320

aggacttgga aggagtagat atcatcctag gtgtctgctc tagtggcctt ctggtttaca     1380

aagataagct gagaattaac cgcttccctt ggcccaaagt gctgaagatt tcttataaac     1440

gtagtagctt tttcatcaag attcggcctg gagagcaaga gcagtatgaa agtaccatcg     1500

gattcaaact tcccagttac cgagcagcta agaaattatg gaaagtctgt gtagaacatc     1560

acacgttttt cagattgaca tctacagaca ccattcccaa aagcaaattt cttgcgctag     1620

gatccaaatt tcgatacagt ggccggactc aagctcagac caggcaagct agtgctctaa     1680

ttgacaggcc tgccccacac ttcgagcgta cagcaagtaa acgggcgtcc cggagcctcg     1740

atggagcagc agctgtcgat tcggcagacc gaagtcctcg gcccacttct gcacctgcca     1800

ttactcaggg tcaggttgca gaaggtggcg tcctagatgc ctctgctaaa aaaacagtgg     1860

tccctaaagc acagaaggaa acagtgaagg ctgaagtgaa aaaggaagac gagccacctg     1920

agcaagctga gccagagccc acagaagcat ggaaggattt agacaagagt caagaggaga     1980

tcaaaaaaca tcatgccagc atcagtgagc tgaaaaagaa cttcatggag tctgtaccag     2040

aaccacggcc tagtgaatgg gataaacgct tatccactca ctcacccttc cgaactctta     2100

acatcaatgg gcaaatcccc acaggagaag gacctcccct ggtgaagaca caaactgtca     2160

ccatctcaga taatgccaat gctgtgaaaa gtgaaatccc aaccaaagac gtccctattg     2220

tccacactga gaccaagacc atcacttatg aggctgccca gactgacgac aacagtggag     2280

acttggaccc aggagtcttg ctgacagctc aaactatcac atctgagacc ccaagcagca     2340

ccaccacaac tcaaattacc aagactgtaa aaggtgggat ttcagagaca cgtattgaaa     2400

agagaattgt gatcacagga gatgctgata ttgaccatga tcaggtcctt gtacaagcca     2460

tcaaggaggc aaaggagcag cacccagaca tgtcagtgac caaggtggtc gtccaccagg     2520

agaccgagat tgctgatgag tgagctcagg aactaaccta ccccaactct gcccttctcc     2580

catccaagag aaaccagcaa aatgataaag aagctaacct gccatagtca gacttcagac     2640

tttcaagatt attctaaatc accagaaaat taatttcagt ttctattggg agtttatacc     2700

aagagattct tctagatctc attgatcctt ttgaagagct ttttctatat taggatatca     2760

gaattgttca acttttcact ctatagactg ttttaagagt tttggggttt ttttaattgg     2820

gtggtttgta accccttcag cctagcctct ctgcccattt atttccaacc ccaacagaca     2880

ctgacagggt ccatggaatt cttcgggaaa tcctccaagg actcttgtca gctgtgttgg     2940

aagccaaagc cagcttagtg ggacttccgc gtctctccct agtcttatcc cctttggatg     3000

atggcagaaa cttcatgaac cagccctttc tcagagccag tgatgtgagt gtatcagaat     3060

gccagggagg gcaccagccc tgatccacag acctcggaaa gatgcccctg ttcctttgtt     3120

gcgggtggtt ttggtaaggc agagccctct gctgagaatg tagtattgtt tttcccctct     3180

ccctcctgct ttctttttgg agcttctttg ggtcaaagac atggaagttg cttcagatat     3240

ctgatactgt gaatgtttga acatatccgt ggccttcacc tctccagcta cccttttacc     3300

tcatcagaag cagtggctca gctaagtgct ccccctagct cccatctcag gagaccaaat     3360

ctcacagaaa aataggcact ttgggccaaa agctctaatg gaacattttt agtggtgatt     3420

tggggaagga aagttaatga ggtttttaaa ataaggtttt ctagttttga gagtgtgcac     3480

ttcacacagg ggaatggggt tacttctgtc tgatcctggg cctttctttc atcccaaatg     3540

acaaggaatg tggctcagag aagggttttt cttttttgac ctttcttctc tcaacaggaa     3600

cctgcctgag gacacccttc tagagcaagg aattgacttt taggagccgt tctccccaca     3660

agacaccaca tgacaagggg tataagcccc agccctgctc attcccactc accagctgag     3720

gtctgtcagg ttttgaaggc ttgattttgt ggtgggtttg gggcttagtt ttcctttttt     3780

tcattttgat ttttgaaagt gaagatgatg ccctaattcc tggtaaggat ttggggcata     3840

gttttttgtt tttttgagac ggagtttcgc tcttgttgcc caagctggag tgcagtggcg     3900

cgatctcggc tcactgcaac ctccgcctcc tgggttcaag cagttctctt gcctcagcct     3960

cccaagtagc tgggatgaca ggcgcacacc accacgccca gcaaattttt tgtattttta     4020

gtagaaacgg gatttcacct tgttaggctg gtctcgaact cctgacctca ggtgatccac     4080

ccaccttggc ctcccaaagt gctgggatta caggtgtgag ccaccacgcc cggccgattt     4140

ggggcatttt tatttaacag aacttctcta accttccaac tgcttcccac aaacacattg     4200

gcctcaaggc tccttagaat cccagttcca gcttcctaaa atagacagtg ggtatcgggc     4260

agcagtcact ggggctcaag ggcagtgagc aagagaaatg tctaaagctg cttctcccaa     4320

caccgtccaa agtctccact gcctgagttt tgtttcggct ggtttgaact catttcgggt     4380

gtgtgcattt ttcttttggt acccatgtga gacatgaaca acaggaggga gggaaagagc     4440

ccaggtggga cgtgggacag gcttagggga aagagcttgt cctatctcag gaacaaaatt     4500

ataggctgtg ggcagagggt ctgaaaggtg ggctttgggg tagtgcccaa gcctggtcgt     4560

gttgccagga gtggtgacaa gaaatgcagc ttacatcaaa cgaacatgta gtgcatgccc     4620

actgcctgat ggccagatgg cctgtaggaa gagctaccag ggcttccaga cctgtggaac     4680

gaagaggatg gggaaaaggc agagggcact gagtgtccct ttaaaaacta acccactgaa     4740

tattccgtgt gatctagaac agtgtggcag ctttcacagc acaggaccgt tcatcggggg     4800

cctaaacgtt tccctcagct ctgtcaccaa ctcacttctc tcggcttcgt tgtctgtaaa     4860

ttggatgaaa agagctctaa tgcctttcag gctcttagaa gccatagatt tggacaagcc     4920

cagcaagatg ggtgtccttc caggcctctt cccctttcct ccatctctgg caacagttct     4980

tggggtttgg caattgtttg gatttttttt ctttctgcag ttgtgtgtat gtgtgtttgt     5040

gtgaagaaaa acagactctg tccaggtaga aatggtgagg agggggaaga gaattacatt     5100

tccagggtca gaaacttggc aacagttttc ctagagtgac tcagacacac cacagtaaca     5160

actctcgctg caattttatt ttaatttgag aaataaagat ttcctccaag ccacatgagg     5220

actctggcac ccacccacaa agcaagacct gtatttataa gccgagggct cagggagcct     5280

aactgcggga cccgtcaggg ccccgtgacc catccccgtc cccacccccc cctccaccgc     5340

tgggcccatc agtgtgtgtt ggggggatgc ttggcagctg ggggtgagga gacaacaaac     5400

ctcgggaact ggagccagag ctgcggcctg actgacgcct tttgatgctc acgggaaatt     5460

tctgcccagg atctcagccc caggctggtt gtttctacaa atctctctca aatgtattat     5520

tttggtgaca aaaatgaagg agctttgtaa atttttttta aaattatgaa tcatatcaag     5580

tagttgttta catttcttga aaaaatagga actcgggcag cagaatcaga ttggcagaat     5640

ctttagacta cacaggcaat aatcaagtct gctgttttgg cctttcgtag tagaagtggt     5700

tgtagtgttt agatatctgt ttggtcttgc ttcttgtatt gcattttttt caataaacaa     5760

caacaaaaag aactctcaaa aa                                              5782


<210>  487
<211>  4749
<212>  DNA
<213>  homo sapiens

<400>  487
tttcagttgg aaggaggtag ggaaaataag tgctttaatt cctaggattt tggaagtaaa       60

aatggaacac cagacaaaaa tggaattttt aggcaaatgt aaagctttgt acttgggtat      120

ctcaaagtat tatacagtgt aaactatcat gattattaac caactagaag tagttctttt      180

ttttaaattt tatttttaat tttagacatg agggtcttgc tatgttgccc aggctgaagt      240

ggctactgac aggcacgatg tggcactgca gcctggaact cttgggctta agtgatcctt      300

cctgcttctt ctatcttaaa aaaaaaaagt tacgcttgct tgttaaaata tttttaaaat      360

gctgtgttta aactaagaag taaatatcca ccccacctct gacttctaaa aattatctaa      420

agtatgactg gtaagatttt tacctttaat cccacataag tctaaaattt gtgttcattt      480

ccaacaacca aagtgtgtca cttttatacc agaattttgt cctgcttata cgtttagtac      540

agaaatctca tgggagagag catccatgca tttacaaatt gttattgaat tattttattg      600

aatgatgaca cccaaactga gctagaacat aattctggct ctgctagtac atcttctgtg      660

tgatcttgga caagtcactc tactttcctt tcaattttct tttctcacag ggagataatc      720

ataaaaacga ctgtaaagta cagcacttca tagagtgctt tttgtttaaa gagctgacaa      780

taaatacgag tctcaaggtc taggaaagcc tccctcacaa cctgagctgc ttgaggacaa      840

gggattttct tttgaatcag cagtacctta tttgtgtatc tgtgatagag ttcctggtac      900

ataagaaggt ctcaataaat atgtgaattt atgaatatta ggcagattgc aaccttgaca      960

ggccactgcc tcttaaatct cctttctgtg atcttttaat atttaacatc taaaaggccg     1020

ccgctacttg ctttgggata agtatccccg gtatgtactt taaaatgccc aagcctagag     1080

aaatgattct tgtcttaagg gcaccatttc gctctcccac cgtaaagcgc cccaggcttg     1140

ggatctgggt cccaaggcta cagggaagag tttggaacgg gaagctcatc ttccggccct     1200

ctgattggcc ggctcgcact ccactcacgc ggcgcgcagc tctgattggc ctcggcggca     1260

cccctcgtcc cgcgactact ttgtgtgctg gggcggcgcg ctccggtcct cccgctcagc     1320

tggcggtctg ggctgctctg gggcagccct tcggtccact gctctgcatc gcgggcgccg     1380

ggaattttcc gagtccgagc gggttgctgc ttttgctcag aggacatcca tgaccctaat     1440

ggtctttttg ttcaagataa agtgattttt tgcctttgtt gattaactgg acaaattcag     1500

gataccagaa ggccctattg atcaggggcc agctatagga agagtacgcg ttttagaaga     1560

gcagcttgtt aaggccaaag aacagattga aaattacaag aaacagacca gaaatggtct     1620

ggggaaggat catgaaatcc tgaggaggag gattgaaaat ggagctaaag agctctggtt     1680

tttcctacag agtgaattga agaaattaaa gaacttagaa ggaaatgaac tccaaagaca     1740

tgcagatgaa tttcttttgg atttaggaca tcatgaaagg tctataatga cggatctata     1800

ctacctcagt cagacagatg gagcaggtga ttggcgggaa aaagaggcca aagatctgac     1860

agaactggtt cagcggagaa taacatatct tcagaatccc aaggactgca gcaaagccaa     1920

aaagctggtg tgtaatatca acaaaggctg tggctatggc tgtcagctcc atcatgtggt     1980

ctactgcttc atgattgcat atggcaccca gcgaacactc atcttggaat ctcagaattg     2040

gcgctatgct actggtggat gggagactgt atttaggcct gtaagtgaga catgcacaga     2100

cagatctggc atctccactg gacactggtc aggtgaagtg aaggacaaaa atgttcaagt     2160

ggtcgagctt cccattgtag acagtcttca tccccgtcct ccatatttac ccttggctgt     2220

accagaagac ctcgcagatc gacttgtacg agtgcatggt gaccctgcag tgtggtgggt     2280

gtctcagttt gtcaaatact tgatccgccc acagccttgg ctagaaaaag aaatagaaga     2340

agccaccaag aagcttggct tcaaacatcc agttattgga gtccatgtca gacgcacaga     2400

caaagtggga acagaagctg ccttccatcc cattgaagag tacatggtgc atgttgaaga     2460

acattttcag cttcttgcac gcagaatgca agtggacaaa aaaagagtgt atttggccac     2520

agatgaccct tctttattaa aggaggcaaa aacaaagtac cccaattatg aatttattag     2580

tgataactct atttcctggt cagctggact gcacaatcga tacacagaaa attcacttcg     2640

tggagtgatc ctggatatac attttctctc tcaggcagac ttcctagtgt gtactttttc     2700

atcccaggtc tgtcgagttg cttatgaaat tatgcaaaca ctacatcctg atgcctctgc     2760

aaacttccat tctttagatg acatctacta ttttgggggc cagaatgccc acaatcaaat     2820

tgccatttat gctcaccaac cccgaactgc agatgaaatt cccatggaac ctggagatat     2880

cattggtgtg gctggaaatc attgggatgg ctattctaaa ggtgtcaaca ggaaattggg     2940

aaggacgggc ctatatccct cctacaaagt tcgagagaag atagaaacgg tcaagtaccc     3000

cacatatcct gaggctgaga aataaagctc agatggaaga gataaacgac caaactcagt     3060

tcgaccaaac tcagttcaaa ccatttcagc caaactgtag atgaagaggg ctctgatcta     3120

acaaaataag gttatatgag tagatactct cagcaccaag agcagctggg aactgacata     3180

ggcttcaatt ggtggaattc ctctttaaca agggctgcaa tgccctcata cccatgcaca     3240

gtacaataat gtactcacat ataacatgca aacaggttgt tttctacttt gcccctttca     3300

gtatgtcccc ataagacaaa cactgccata ttgtgtaatt taagtgacac agacattttg     3360

tgtgagactt aaaacatggt gcctatatct gagagacctg tgtgaactat tgagaagatc     3420

ggaacagctc cttactctga ggaagttgat tcttatttga tggtggtatt gtgaccactg     3480

aattcactcc agtcaacaga ttcagaatga gaatggacgt ttggtttttt tttgtttttg     3540

tttttgtttt ttcctttata aggttgtctg tttttttttt tttaaataat tgcatcagtt     3600

cattgacctc atcattaata agtgaagaat acatcagaaa ataaaatatt cactctccat     3660

tagaaaattt tgtaaaacaa tgccatgaac aaattcttta gtactcaatg tttctggaca     3720

ttctctttga taacaaaaaa taaattttaa aaaggaattt tgtaaagttt ctagaatttt     3780

atatcattgg atgatatgtt gatcagcctt atgtggaaga actgtgataa aaagaggagc     3840

tttttagttt ttcagcttat ttactttgtt ttttttcctg tttctgatat agtaactaat     3900

tcttaactca gagacattgg tccattttaa tactgaaaac caattttcat tggtacacat     3960

tacaaaattg ctaagaacac tgtttgggag ctttcattct catattttgg acattgtttt     4020

aattgagtga aataatcata actccttgct cccagagaag ctatcacctc catttctaaa     4080

accatttcag gtttgtttgg tagtctttct taatgtattt attatcgctt tttgtgagta     4140

gggtcctgtt ttatccagga accaatttct gccctagcct atcatgccct gcttttgaga     4200

gtaccaggta tctttgggat tgggaagctg gctgtttcag aagtatatgt ctcatagtgt     4260

gcagaacttg gtgaccaagt gagaagcggg accaatggga gactcacaat ggactgagtc     4320

ttgggattat cttttccaaa ttcttccatg ttagaatcac ttcagaaaat aagactttga     4380

tgctttgtct ctgagcatca tttttctcct cataaaaaca cttccttatt gtatgtagcc     4440

tgcctcctac agaggcctgg taggtgttac tgcattctaa aagaaaaatg tcatctctgt     4500

aggagcgact atcaggccta gtgtgaaata ttagggatcc taggcagaag agctattagt     4560

cctggccttc atatcttcac caaatgaaaa tactgtatat aaaatttcac caccaaactt     4620

aactaaattc tttttctcaa gtcaagcctc ccaaagaaaa aagaaattaa cttcctacag     4680

tgtcagcaag caattttcca tttagttttg gtacaaataa aagtcatttg aaacaaaaaa     4740

aaaaaaaaa                                                             4749


<210>  488
<211>  5179
<212>  DNA
<213>  homo sapiens

<400>  488
tttcagttgg aaggaggtag ggaaaataag tgctttaatt cctaggattt tggaagtaaa       60

aatggaacac cagacaaaaa tggaattttt aggcaaatgt aaagctttgt acttgggtat      120

ctcaaagtat tatacagtgt aaactatcat gattattaac caactagaag tagttctttt      180

ttttaaattt tatttttaat tttagacatg agggtcttgc tatgttgccc aggctgaagt      240

ggctactgac aggcacgatg tggcactgca gcctggaact cttgggctta agtgatcctt      300

cctgcttctt ctatcttaaa aaaaaaaagt tacgcttgct tgttaaaata tttttaaaat      360

gctgtgttta aactaagaag taaatatcca ccccacctct gacttctaaa aattatctaa      420

agtatgactg gtaagatttt tacctttaat cccacataag tctaaaattt gtgttcattt      480

ccaacaacca aagtgtgtca cttttatacc agaattttgt cctgcttata cgtttagtac      540

agaaatctca tgggagagag catccatgca tttacaaatt gttattgaat tattttattg      600

aatgatgaca cccaaactga gctagaacat aattctggct ctgctagtac atcttctgtg      660

tgatcttgga caagtcactc tactttcctt tcaattttct tttctcacag ggagataatc      720

ataaaaacga ctgtaaagta cagcacttca tagagtgctt tttgtttaaa gagctgacaa      780

taaatacgag tctcaaggtc taggaaagcc tccctcacaa cctgagctgc ttgaggacaa      840

gggattttct tttgaatcag cagtacctta tttgtgtatc tgtgatagag ttcctggtac      900

ataagaaggt ctcaataaat atgtgaattt atgaatatta ggcagattgc aaccttgaca      960

ggccactgcc tcttaaatct cctttctgtg atcttttaat atttaacatc taaaaggccg     1020

ccgctacttg ctttgggata agtatccccg gtatgtactt taaaatgccc aagcctagag     1080

aaatgattct tgtcttaagg gcaccatttc gctctcccac cgtaaagcgc cccaggcttg     1140

ggatctgggt cccaaggcta cagggaagag tttggaacgg gaagctcatc ttccggccct     1200

ctgattggcc ggctcgcact ccactcacgc ggcgcgcagc tctgattggc ctcggcggca     1260

cccctcgtcc cgcgactact ttgtgtgctg gggcggcgcg ctccggtcct cccgctcagc     1320

tggcggtctg ggctgctctg gggcagccct tcggtccact gctctgcatc gcgggcgccg     1380

ggaattttcc gagtccgagc gggttgctgc ttttgctcag aggacatcca tgaccctaat     1440

ggtctttttg ttcaagataa agtgattttt tgcctttgtt gattaactgg acaaattcag     1500

catgtagagc gcatgaagta caggacaata aagcttccta cacatatcac caggaggatc     1560

tctttgaaag attcactgca ggactaccag agagaataat ttgtctgaag catcatgtgt     1620

tgaaacaaca gaagtctatt cacctgtgca ctaactagaa acagagttac aatgttttca     1680

attctttgag ctccaggact ccagggaagt gagttgaaaa tctgaaaatg cggccatgga     1740

ctggttcctg gcgttggatt atgctcattc tttttgcctg ggggaccttg ctgttttata     1800

taggtggtca cttggtacga gataatgacc atcctgatca ctctagccga gaactgtcca     1860

agattctggc aaagcttgaa cgcttaaaac aacagaatga agacttgagg cgaatggccg     1920

aatctctccg gataccagaa ggccctattg atcaggggcc agctatagga agagtacgcg     1980

ttttagaaga gcagcttgtt aaggccaaag aacagattga aaattacaag aaacagacca     2040

gaaatggtct ggggaaggat catgaaatcc tgaggaggag gattgaaaat ggagctaaag     2100

agctctggtt tttcctacag agtgaattga agaaattaaa gaacttagaa ggaaatgaac     2160

tccaaagaca tgcagatgaa tttcttttgg atttaggaca tcatgaaagg tctataatga     2220

cggatctata ctacctcagt cagacagatg gagcaggtga ttggcgggaa aaagaggcca     2280

aagatctgac agaactggtt cagcggagaa taacatatct tcagaatccc aaggactgca     2340

gcaaagccaa aaagctggtg tgtaatatca acaaaggctg tggctatggc tgtcagctcc     2400

atcatgtggt ctactgcttc atgattgcat atggcaccca gcgaacactc atcttggaat     2460

ctcagaattg gcgctatgct actggtggat gggagactgt atttaggcct gtaagtgaga     2520

catgcacaga cagatctggc atctccactg gacactggtc aggtgaagtg aaggacaaaa     2580

atgttcaagt ggtcgagctt cccattgtag acagtcttca tccccgtcct ccatatttac     2640

ccttggctgt accagaagac ctcgcagatc gacttgtacg agtgcatggt gaccctgcag     2700

tgtggtgggt gtctcagttt gtcaaatact tgatccgccc acagccttgg ctagaaaaag     2760

aaatagaaga agccaccaag aagcttggct tcaaacatcc agttattgga gtccatgtca     2820

gacgcacaga caaagtggga acagaagctg ccttccatcc cattgaagag tacatggtgc     2880

atgttgaaga acattttcag cttcttgcac gcagaatgca agtggacaaa aaaagagtgt     2940

atttggccac agatgaccct tctttattaa aggaggcaaa aacaaagtac cccaattatg     3000

aatttattag tgataactct atttcctggt cagctggact gcacaatcga tacacagaaa     3060

attcacttcg tggagtgatc ctggatatac attttctctc tcaggcagac ttcctagtgt     3120

gtactttttc atcccaggtc tgtcgagttg cttatgaaat tatgcaaaca ctacatcctg     3180

atgcctctgc aaacttccat tctttagatg acatctacta ttttgggggc cagaatgccc     3240

acaatcaaat tgccatttat gctcaccaac cccgaactgc agatgaaatt cccatggaac     3300

ctggagatat cattggtgtg gctggaaatc attgggatgg ctattctaaa ggtgtcaaca     3360

ggaaattggg aaggacgggc ctatatccct cctacaaagt tcgagagaag atagaaacgg     3420

tcaagtaccc cacatatcct gaggctgaga aataaagctc agatggaaga gataaacgac     3480

caaactcagt tcgaccaaac tcagttcaaa ccatttcagc caaactgtag atgaagaggg     3540

ctctgatcta acaaaataag gttatatgag tagatactct cagcaccaag agcagctggg     3600

aactgacata ggcttcaatt ggtggaattc ctctttaaca agggctgcaa tgccctcata     3660

cccatgcaca gtacaataat gtactcacat ataacatgca aacaggttgt tttctacttt     3720

gcccctttca gtatgtcccc ataagacaaa cactgccata ttgtgtaatt taagtgacac     3780

agacattttg tgtgagactt aaaacatggt gcctatatct gagagacctg tgtgaactat     3840

tgagaagatc ggaacagctc cttactctga ggaagttgat tcttatttga tggtggtatt     3900

gtgaccactg aattcactcc agtcaacaga ttcagaatga gaatggacgt ttggtttttt     3960

tttgtttttg tttttgtttt ttcctttata aggttgtctg tttttttttt tttaaataat     4020

tgcatcagtt cattgacctc atcattaata agtgaagaat acatcagaaa ataaaatatt     4080

cactctccat tagaaaattt tgtaaaacaa tgccatgaac aaattcttta gtactcaatg     4140

tttctggaca ttctctttga taacaaaaaa taaattttaa aaaggaattt tgtaaagttt     4200

ctagaatttt atatcattgg atgatatgtt gatcagcctt atgtggaaga actgtgataa     4260

aaagaggagc tttttagttt ttcagcttat ttactttgtt ttttttcctg tttctgatat     4320

agtaactaat tcttaactca gagacattgg tccattttaa tactgaaaac caattttcat     4380

tggtacacat tacaaaattg ctaagaacac tgtttgggag ctttcattct catattttgg     4440

acattgtttt aattgagtga aataatcata actccttgct cccagagaag ctatcacctc     4500

catttctaaa accatttcag gtttgtttgg tagtctttct taatgtattt attatcgctt     4560

tttgtgagta gggtcctgtt ttatccagga accaatttct gccctagcct atcatgccct     4620

gcttttgaga gtaccaggta tctttgggat tgggaagctg gctgtttcag aagtatatgt     4680

ctcatagtgt gcagaacttg gtgaccaagt gagaagcggg accaatggga gactcacaat     4740

ggactgagtc ttgggattat cttttccaaa ttcttccatg ttagaatcac ttcagaaaat     4800

aagactttga tgctttgtct ctgagcatca tttttctcct cataaaaaca cttccttatt     4860

gtatgtagcc tgcctcctac agaggcctgg taggtgttac tgcattctaa aagaaaaatg     4920

tcatctctgt aggagcgact atcaggccta gtgtgaaata ttagggatcc taggcagaag     4980

agctattagt cctggccttc atatcttcac caaatgaaaa tactgtatat aaaatttcac     5040

caccaaactt aactaaattc tttttctcaa gtcaagcctc ccaaagaaaa aagaaattaa     5100

cttcctacag tgtcagcaag caattttcca tttagttttg gtacaaataa aagtcatttg     5160

aaacaaaaaa aaaaaaaaa                                                  5179


<210>  489
<211>  4957
<212>  DNA
<213>  homo sapiens

<400>  489
aatgagctgt ctgcagcaga gctgagagga ccagccattt tacttatgga aaacagtgtg       60

gcatattctg ctgagcttcg ccctggaaga agcctctttt atacatctct tcagggaaga      120

gagaagcaat gggcatgtta gtatacaatg atcacagcca cgcaggcctg caagctgcct      180

tttggacagg ctgttgactg ccgttccaat tagctgattg gagaatgtgg aatgcagagt      240

gataatgctg catatctgct atcaggcagc agcaaaggtt tttgtcttgg gaaggcaagc      300

tttccctgca atattatctc agcagctccc tagctgctta ccctgaaaac gagggatcca      360

aacggagggt gttgcactct gctaacgctg gtcctgtgcg tggctgtggc atatgagcgg      420

caggtctgaa aaagcaggtg tgtgctggga cgggcactgg actggaacgc aggcggacgc      480

tctcgggttt acctgcttcc tgttaacaga ttgtgggctc ccagggcata tgtctgcacg      540

ctgaggccga ggcggagaag gggcttcctg agcgtcccag tacactgaca gagacacttg      600

gattggactt aatcttaaac ctctggagtt caagaccttt taaaaagggc taaataaaca      660

atctctacat gtaaaaggcc actgactcct acttcctctg tatagagcaa ctgttgaact      720

cagctgcctg taggaaaact gaagacttta ataacaaact ctccaaggtg aaaatgaaca      780

cagggcgtga ttctcagtca ccagactcag caaaaggttt tagaagcgtt cgaccaaacc      840

tacaagataa aagatcacca actcagagcc agataacagt gaatggaaac tcaggaggtg      900

ccgtgagtcc catgagttac tatcagaggc cgttttcccc ctcggcatat tctctcccag      960

cctcactcaa ctccagcatt gtcatgcagc acggcacatc cctcgattcc acagacacat     1020

atccccagca tgcgcagtct ctggatggca ccaccagcag ctctatcccc ctgtaccgat     1080

cctcagagga agagaagaga gtgacagtca tcaaagcccc gcattaccca gggatcgggc     1140

ccgtggatga atccggaatc cccacagcaa ttagaacgac agtcgaccgg cccaaggact     1200

ggtacaagac gatgtttaag caaattcaca tggtgcacaa gccggatgat gacacagaca     1260

tgtataatac tccttataca tacaatgcag gtctgtacaa cccaccctac agtgctcagt     1320

cacaccctgc tgcaaagacc caaacctaca gacctctttc caaaagccac tccgacaaca     1380

gccccaatgc ctttaaggat gcgtcctccc cagtgcctcc cccacatgtt ccacctccag     1440

tcccgccgct tcgaccaaga gatcggtctt caacagaaaa gcatgactgg gatcctccag     1500

acagaaaagt ggacacaaga aaatttcggt ctgagccaag gagtattttt gaatatgaac     1560

ctggcaagtc atcaattctt cagcatgaaa gaccaactga tcgcataaat ccagatgaca     1620

tagatttaga aaatgagccc tggtataaat tcttttcaga actggagttt ggacgcccgc     1680

ctcctaaaaa gcctctggac tatgttcaag atcattcttc tggtgttttc aatgaggcct     1740

ccttgtatca gtcctctata gacagaagcc tggaaagacc catgagttct gcaagcatgg     1800

ccagtgactt caggaagcgg aggaagagcg agcctgcagt gggtccacca cggggcttgg     1860

gagatcaaag tgcgagcagg actagcccag gccgagtgga cctcccagga tcaagcacca     1920

ctcttacaaa gtctttcact agctcttctc cttcttcccc atcaagagca aaagaccgtg     1980

agtcccctag aagttactca tccactttga ctgacatggg gagaagtgca ccaagggaaa     2040

gaagaggaac tccagaaaaa gagaaattgc ctgcaaaagc tgtttatgat tttaaggctc     2100

agacatctaa ggagttgtca tttaagaaag gagatactgt ctacatcctc aggaaaattg     2160

atcaaaattg gtatgaggga gaacaccacg ggagagtggg catcttcccg atctcatacg     2220

tagagaaact cacacctcct gagaaagcac agcctgcaag accacctccg ccagcccagc     2280

ccggagaaat cggagaagct atagccaaat acaacttcaa cgcagacaca aatgtggagc     2340

tgtcactgag aaagggagat agagttattc ttcttaaaag agttgatcaa aactggtatg     2400

aaggtaaaat cccaggaacc aacagacaag gcatcttccc tgtttcctat gtggaggtcg     2460

tcaagaagaa cacaaaaggt gctgaggact accctgaccc tccaataccc cacagctatt     2520

ctagtgatag gattcacagc ttgagctcaa ataagccaca gcgtcctgtg tttactcatg     2580

aaaatattca aggtgggggg gaaccgtttc aggctctgta taactatact cccaggaatg     2640

aagatgagct ggagctcaga gaaagtgatg tcattgatgt catggaaaag tgtgatgacg     2700

gctggtttgt ggggacctca agaagaacca aattctttgg tactttcccc ggaaactacg     2760

tcaagaggct gtgaattgcg ctccctcctt ctgtagaggc cgcctgccag ccatgcacct     2820

gcgtcaacgc gcctgaaaca ccccgcgggc ctcccgttgt catgccttac ggtttccaat     2880

gcgccgtcac catctccacc tgccaccaaa ccaccagcag agtagccgcc gctgctgtga     2940

gcctggggac gacatggcag gctggtcccc ctccgtgaaa gtgtggattc ctacttcctg     3000

ctctaagctt tgacacgtca aaatgtggga tcagaaagaa aaaaatcatg atatttaaaa     3060

atggtcaaat atttgaggca aaaaaaaaaa aaaaaagtgt ctccaggagg ctgtccagcc     3120

tcgtggctcc atttcaacat ctccccccag gcgatgttct cccccaagac gaccagaaaa     3180

ttgtttattg gggaatgctg tggtttgcat tttcatattc ttcgcttggc agtgtgtatt     3240

cttttcacaa gtttgcctag tgtcttggtt tacacaatat gacaactgta actgtacttt     3300

agctattgtt tgcctgcaca tacatgttgt aatatgcaca gtgattacaa cctttaaagc     3360

aagaggaggc gagttaattt ggatgagtgt gattttgctg attgaatgtg agttttcaaa     3420

taggagtctt tttctgcaat ttgtttgcat tttttagaag tgcaaacagt aagtaaataa     3480

aagccttcgg taataatcat gacaatacaa gaggctgagc taggctacag gggaaaacta     3540

ttgtgttgta aagttgcatc gctattttat attaaaatgt aatgatcagc atcatgaaca     3600

atgagctctt agtgttttat ttatctgaaa aaatgtaagt aaaagcagtg ttagtgagag     3660

gtgcaaagaa ttattctaac agacacctga aagtatctgt aagcaatact agtaggtaag     3720

atttcactgt gtgtacacat acacatttga gattgtatga gaacatataa tccatatgat     3780

atgttgtaca ttttatggaa atgtaataga atctcacaca ttattttata gaaatagagt     3840

acagaagcat cacaagtatt aaagttggtt ttagcaagga ttaggattac tacaattatt     3900

tttactataa taattatttt tcttctatgg aactcagaat cctggctaca tttgaggaca     3960

ggaatatgtt gagcctgatt ttcctggtgt gtgtaaaata tttcctagga ataaattagg     4020

cactttttag aagcaatgtt aaatcattca ggttttattt tctgccctga agcagaaatt     4080

taaaaaatga tattgggacc tggaaggttt aatatggttc acagtgcctg aattacacct     4140

gctccgaaaa ctagctttgt atttcttatg actttgcata agaactgttc atctttggat     4200

cttgagcacc ttacagataa aactttttat ggcatctctt tcatggacag tgatattgat     4260

cttttcacaa tgtacgtagc ctctagaatt ttgtacatat gtttgctctt tttttgtaca     4320

gactagttgt tgagaaaaca ggggcgtttc ctaatttggt ctttatcctg cgacaacact     4380

ttcagcagac tagcctctcc ttatctcaca gatcacaagc acccctagat agtgtgattc     4440

tgtcagatag catttatgca aaaatctatg aagttaaaag atcgtagaag ccaaatgaaa     4500

tgtacatatc tactgactga tgacaaggga atttcattag gaagaaggta aagaaacatc     4560

gttgagtagc ctaccttgat ttctgtcaag ttcataacca gcttcatatt ttaaaggctt     4620

caggtttgaa attaagtcaa ctgcatgcag ctttgctgat aaatgaataa ttctctttga     4680

tgccatttat gagaaaagac ttcaatatct gttgcctgtc atatttaaga aaaattactg     4740

tttctactct ctgtatctga ttttaaaaga aaaaactatt catacctggc ttccaggtaa     4800

ttgactttga attcttacaa gcaaaggtca ttgtgttttt cttgaataga catctaataa     4860

attttgcttg gaagtatact tcagtttttc ttcttgacat ttatctttat aaaaattgtg     4920

tattttattc caacttgtta aactaagaga aaatgca                              4957


<210>  490
<211>  1634
<212>  DNA
<213>  homo sapiens

<400>  490
gggtggggaa gcttagagac cggtgaggga gcagagctgg ggcgcctgtg tacagggata       60

gagcccggcg gcagcagggc gcggcttccc tttcccgggg cctggggccg caatcaggtg      120

gagtcgagag gccggaggag gggcaggagg aaggggtgcg gtcgcgatcc ggacccggag      180

ccagcgcgga gcacctgcgc ccgcggctga caccttcgct cgcagtttgt tcgcagttta      240

ctcgcacacc agtttccccc accgcgcttt ggattagtgt gatctcagct caaggcaaag      300

gtgggatatc atggcatcta tctgggttgg acaccgagga acagtaagag attatccaga      360

ctttagccca tcagtggatg ctgaagctat tcagaaagca atcagaggaa ttggaactga      420

tgagaaaatg ctcatcagca ttctgactga gaggtcaaat gcacagcggc agctgattgt      480

taaggaatat caagcagcat atggaaagga gctgaaagat gacttgaagg gtgatctctc      540

tggccacttt gagcatctca tggtggccct agtgactcca ccagcagtct ttgatgcaaa      600

gcagctaaag aaatccatga agggcgcggg aacaaacgaa gatgccttga ttgaaatctt      660

aactaccagg acaagcaggc aaatgaagga tatctctcaa gcctattata cagtatacaa      720

gaagagtctt ggagatgaca ttagttccga aacatctggt gacttccgga aagctctgtt      780

gactttggca gatggcagaa gagatgaaag tctgaaagtg gatgagcatc tggccaaaca      840

agatgcccag attctctata aagctggtga gaacagatgg ggcacggatg aagacaaatt      900

cactgagatc ctgtgtttaa ggagctttcc tcaattaaaa ctaacatttg atgaatacag      960

aaatatcagc caaaaggaca ttgtggacag cataaaagga gaattatctg ggcattttga     1020

agacttactg ttggccatag ttaattgtgt gaggaacacg ccggcctttt tagccgaaag     1080

actgcatcga gccttgaagg gtattggaac tgatgagttt actctgaacc gaataatggt     1140

gtccagatca gaaattgacc ttttggacat tcgaacagag ttcaagaagc attatggcta     1200

ttccctatat tcagcaatta aatcggatac ttctggagac tatgaaatca cactcttaaa     1260

aatctgtggt ggagatgact gaaccaagaa gataatctcc aaaggtccac gatgggcttt     1320

cccaacagct ccaccttact tcttctcata ctatttaaga gaacaagcaa atataaacag     1380

caacttgtgt tcctaacagg aattttcatt gttctataac aacaacaaca aaagcgatta     1440

ttattttaga gcatctcatt tataatgtag cagctcataa atgaaattga aaatggtatt     1500

aaagatctgc aactactatc caacttatat ttctgctttc aaagttaaga atctttatag     1560

ttctactcca ttaaatataa agcaagataa taaaaattgt tgcttttgtt aaaagtaaaa     1620

aaaaaaaaaa aaaa                                                       1634


<210>  491
<211>  3324
<212>  DNA
<213>  homo sapiens

<400>  491
gacctcgtga aataaaagtg cagaaaacaa acccaggcga tcacagcagc agccgccgcg       60

gcagcagcac caacagcagg aggagcagga ggagccggag gaggaggagg aggaggaggc      120

aaagttagag ttggggctgg cgctccggag ttgctgggct cagcgcagct cccattcatt      180

aaggaaccag ctgcggagga aggtggccga gcgcccgcgc tgcccactcg ctcgctcgcg      240

cactcagacg cgcgccacaa cagcgcgccc caagctgcgc agctctgcaa aagtttctgc      300

tcgggatctg gctctcttcc ccttggactt tagaacgatt tagggttgac agaggaaagc      360

agaggcgcgc aggaggagca gaaaacacca ccttctgcag ttggaggcag gcagccccgg      420

ctgcactcta gccgccgcgc ccggagccgg ggccgacccg ccactatccg cagcagcctc      480

ggccaggagg cgacccgggc gcctgggtgt gtggctgctg ttgcgggacg tcttcgcggg      540

gcgggaggct cgcgccgcag ccagcgccat gcaaaactac aagtacgaca aagcgatcgt      600

cccggagagc aagaacggcg gcagcccggc gctcaacaac aacccgagga ggagcggcag      660

caagcgggtg ctgctcatct gcctcgacct cttctgcctc ttcatggcgg gcctcccctt      720

cctcatcatc gagacaagca ccatcaagcc ttaccaccga gggttttact gcaatgatga      780

gagcatcaag tacccactga aaactggtga gacaataaat gacgctgtgc tctgtgccgt      840

ggggatcgtc attgccatcc tcgcgatcat cacgggggaa ttctaccgga tctattacct      900

gaagaagtcg cggtcgacga ttcagaaccc ctacgtggca gcactctata agcaagtggg      960

ctgcttcctc tttggctgtg ccatcagcca gtctttcaca gacattgcca aagtgtccat     1020

agggcgcctg cgtcctcact tcttgagtgt ctgcaaccct gatttcagcc agatcaactg     1080

ctctgaaggc tacattcaga actacagatg cagaggtgat gacagcaaag tccaggaagc     1140

caggaagtcc ttcttctctg gccatgcctc cttctccatg tacactatgc tgtatttggt     1200

gctatacctg caggcccgct tcacttggcg aggagcccgc ctgctccggc ccctcctgca     1260

gttcaccttg atcatgatgg ccttctacac gggactgtct cgcgtatcag accacaagca     1320

ccatcccagt gatgttctgg caggatttgc tcaaggagcc ctggtggcct gctgcatagt     1380

tttcttcgtg tctgacctct tcaagactaa gacgacgctc tccctgcctg cccctgctat     1440

ccggaaggaa atcctttcac ctgtggacat tattgacagg aacaatcacc acaacatgat     1500

gtaggtgcca cccacctcct gagctgtttt tgtaaaatga ctgctgacag caagttcttg     1560

ctgctctcca atctcatcag acagtagaat gtagggaaaa acttttgccc gactgatttt     1620

taaaaaggaa aaaaaaaatg ttttactatg tggccttcca aaataggtag tgtttgccta     1680

tgtggaaaca acagcaaact aacaccaagt gccagagtcc tggatgtgca attggtttaa     1740

gtgttcatgt tctagtgaac acagcttgtt caggaacaaa cactaaaacg atttgagtag     1800

aggctgctgg tcaccttttg tgacctgagg aatcccaggc ctgtgagaaa agcaaaaatt     1860

cacattgcag cacatgatgc cagaaatagc actgaatcaa gaaaatagcc attgcggagc     1920

tgccctcttg agtctttctg tccatcccat tctattctgt actgtgactt tagttcagga     1980

agttttgttt tgtgttttaa ataaaaggaa agagcaagtt tgctcagtca agtgatcaga     2040

tcccgaatct agattcccag ttctaaggcc ttatcacctc ccctgcccat aggccaacaa     2100

ccatagttcc tcacattagt gattagcaga ctctttgtgg acgagtgaat ttcacaaaca     2160

gcacaatttc agaagaaatc gagggcacag gccctcactt ttcttctttt gacgcatcat     2220

cctgtgatgt tgaaatgtca attgcaggat gctgatgttg tgcacgtcaa tcaccgggca     2280

cttgcatact cttagaaaca gttcgacttc ggttactgcc ttctcccttg aaatccttgc     2340

tgcgtgccca ccaggatttc ctgtgagggc ccaggaatga gcaaggcatg gtctgccacc     2400

agctgacgga aagcagcctt ctgtacaaca gatgggaggg tgaagggggc agaatgaaaa     2460

tcgaaccaac cttttagctg ttgcaaatca gaaggagcca gagaagcagg cagtctcatg     2520

catgagaggt tacccttcag gatgacagag ctgagggtct ttgtaggagt tgctcttgct     2580

gtgtaaagca ctattgtctt ggggttgagc cctagggcag ttcttggtag gttctgctgg     2640

gcagaacata tgggttaaat ctcggtagag agtttccctc atcctctatc cgtaagtgtc     2700

cttccatgca aggtcccact ctaggtgata gacagggacc ccttctactg aacctttgag     2760

gaaaggagga aggaagaaat gcgtttagat cttggatgca gacctttcaa agggttaaat     2820

gtaaccatat ggatcaacca catgcacatc cttactacag aatccgtcct ttcatttcaa     2880

cttatagcaa gctatgattt ttatatataa atattatata aataatgtat aaaacattaa     2940

aagttaacta tgtaagatat tatttctgaa acaatttagc tatatccact atgattataa     3000

actgtgtctc gacctgtgtt atttacatta gctgcttaaa aaagcattga gttaattttt     3060

ttaaatatca actaaaatat catagttctg tggtagacat tgttttataa tgaaataact     3120

gcaactagag aaaactgtat aaaaacatta aattgtcagt atttttgtaa ggttccattt     3180

tgtaaagaga ataatattca aagacttttg tagcatacaa agtgaaaact tgtatctgcg     3240

aaactatact tgtattaaat gtgcttttta aataaaagct cgtaacacaa ctaattaagg     3300

acttgcaaaa aaaaaaaaaa aaaa                                            3324


<210>  492
<211>  2509
<212>  DNA
<213>  homo sapiens

<400>  492
gcacgggctg gtctctgccc taatgcggcg gctggcggcg agaggcgctg caggggacgc       60

gggggaagtg gcggcgccgg cagcggacag ctcggacagc gcccagggcc ggagcccgag      120

cccttggagg ttgattgact tatgtgcaat ttgggacgct ggagtttacc ttccctccgc      180

agcctggaac agagcctcct ctggtgttgc aaggaagagg ctgaatgagg cagagaagct      240

gagtgctgtc caggaggccc agttaaagcg gctcgaggtg acaagacccc gagtgctggg      300

gagcagggag cagggccagg tgccgaggat ggccaggcag ccaccgccgc cctgggtcca      360

tgcagccttc ctcctctgcc tcctcagtct tggcggagcc atcgaaattc ctatggatct      420

gacgcagccg ccaaccatca ccaagcagtc agcgaaggat cacatcgtgg acccccgtga      480

taacatcctg attgagtgtg aagcaaaagg gaaccctgcc cccagcttcc actggacacg      540

aaacagcaga ttcttcaaca tcgccaagga cccccgggtg tccatgagga ggaggtctgg      600

gaccctggtg attgacttcc gcagtggcgg gcggccggag gaatatgagg gggaatatca      660

gtgcttcgcc cgcaacaaat ttggcacggc cctgtccaat aggatccgcc tgcaggtgtc      720

taaatctcct ctgtggccca aggaaaacct agaccctgtc gtggtccaag agggcgctcc      780

tttgacgctc cagtgcaacc ccccgcctgg acttccatcc ccggtcatct tctggatgag      840

cagctccatg gagcccatca cccaagacaa acgtgtctct cagggccata acggagacct      900

atacttctcc aacgtgatgc tgcaggacat gcagaccgac tacagttgta acgcccgctt      960

ccacttcacc cacaccatcc agcagaagaa ccctttcacc ctcaaggtcc tcaccacccg     1020

aggagttgca gaaagaacac caagcttcat gtatccccag ggcaccgcga gcagccagat     1080

ggtgcttcgt ggcatggacc tcctgctgga atgcatcgcc tccggggtcc caacaccaga     1140

catcgcatgg tacaagaaag gtggggacct cccatctgat aaggccaagt ttgagaactt     1200

taataaggcc ctgcgtatca caaatgtctc tgaggaagac tccggggagt atttctgcct     1260

ggcctccaac aagatgggca gcatccggca cacgatctcg gtgagagtaa aggctgctcc     1320

ctactggctg gacgaaccca agaaccttat tctggctcct ggcgaggatg ggagactggt     1380

gtgtcgagcc aatggaaacc ccaaacccac tgtccagtgg atggtgaatg gggaaccttt     1440

gcaatcggca ccacctaacc caaaccgtga ggtggccgga gacaccatca tcttccggga     1500

cacccagatc agcagcaggg ctgtgtacca gtgcaacacc tccaacgagc atggctacct     1560

gctggccaac gcctttgtca gtgtgctgga tgtgccgcct cggatgctgt cgccccggaa     1620

ccagctcatt cgagtgattc tttacaaccg gacgcggctg gactgccctt tctttgggtc     1680

tcccatcccc acactgcgat ggtttaagaa tgggcaagga agcaacctgg atggtggcaa     1740

ctaccatgtt tatgagaacg gcagtctgga aattaagatg atccgcaaag aggaccaggg     1800

catctacacc tgtgtcgcca ccaacatcct gggcaaagct gaaaaccaag tccgcctgga     1860

ggtcaaagac cccaccagga tctaccggat gcccgaggac caggtggcca gaaggggcac     1920

cacggtgcag ctggagtgtc gggtgaagca cgacccctcc ctgaaactca ccgtctcctg     1980

gctgaaggat gacgagccgc tctatattgg aaacaggatg aagaaggaag acgactccct     2040

gaccatcttt ggggtggcag agcgggacca gggcagttac acgtgtgtcg ccagcaccga     2100

gctagaccaa gacctggcca aggcctacct caccgtgcta ggtaactgcc catgctcacc     2160

ctggcactga ccagccccac cccctcccca gcagccagag aagcagtggc ccggggcagt     2220

tccgagggca gtgcctgcag tcaagtggcc gggtcaggcg tggtgatctc ttcttgcctc     2280

gtgatgtcag ggttagggag ctgccagttt cagaacaagc tgtgctggac aggttacctc     2340

ctgagtggag tcattaactt ccccacgtct caactgaaag gggcctgagt gatatagaga     2400

aagtggagag gggtttctcg ttgtgatcat tttacctttc ttacagctaa ctccaccact     2460

aagtcaatta aaacaatcca tccttaaagc aaaaaaaaaa aaaaaaaaa                 2509


<210>  493
<211>  2070
<212>  DNA
<213>  homo sapiens

<400>  493
gccaattgct gaccgccaca gccacagcca gggctagcct cgccggttcc cgggtggcgc       60

gcgttcgctg cctcctcagc tccaggatga tcggccagaa gacgctctac tcctttttct      120

cccccagccc cgccaggaag cgacacgccc ccagccccga gccggccgtc caggggaccg      180

gcgtggctgg ggtgcctgag gaaagcggag atgcggcggc catcccagcc aagaaggccc      240

cggctgggca ggaggagcct gggacgccgc cctcctcgcc gctgagtgcc gagcagttgg      300

accggatcca gaggaacaag gccgcggccc tgctcagact cgcggcccgc aacgtgcccg      360

tgggctttgg agagagctgg aagaagcacc tcagcgggga gttcgggaaa ccgtatttta      420

tcaagctaat gggatttgtt gcagaagaaa gaaagcatta cactgtttat ccacccccac      480

accaagtctt cacctggacc cagatgtgtg acataaaaga tgtgaaggtt gtcatcctgg      540

gacaggatcc atatcatgga cctaatcaag ctcacgggct ctgctttagt gttcaaaggc      600

ctgttccgcc tccgcccagt ttggagaaca tttataaaga gttgtctaca gacatagagg      660

attttgttca tcctggccat ggagatttat ctgggtgggc caagcaaggt gttctccttc      720

tcaacgctgt cctcacggtt cgtgcccatc aagccaactc tcataaggag cgaggctggg      780

agcagttcac tgatgcagtt gtgtcctggc taaatcagaa ctcgaatggc cttgttttct      840

tgctctgggg ctcttatgct cagaagaagg gcagtgccat tgataggaag cggcaccatg      900

tactacagac ggctcatccc tcccctttgt cagtgtatag agggttcttt ggatgtagac      960

acttttcaaa gaccaatgag ctgctgcaga agtctggcaa gaagcccatt gactggaagg     1020

agctgtgatc atcagctgag gggtggcctt tgagaagctg ctgttaacgt atttgccagt     1080

tacgaagttc cactgaaaat tttcctatta attcttaagt actctgcata agggggaaaa     1140

gcttccagaa agcagccatg aaccaggctg tccaggaatg gcagctgtat ccaaccacaa     1200

acaacaaagg ctaccctttg accaaatgtc tttctctgca acatggcttc ggcctaaaat     1260

atgcagaaga cagatgaggt caaatactca gttggctctc tttatctccc ttgcctttat     1320

ggtgaaacag gggagatgtg cacctttcag gcacagccct agtttggcgc ctgctgctcc     1380

ttggttttgc ctggttagac tttcagtgac agatgttggg gtgtttttgc ttagaaaggt     1440

ccccttgtct cagccttgca gggcaggcat gccagtctct gccagttcca ctgccccctt     1500

gatctttgaa ggagtcctca ggcccctcgc agcataagga tgttttgcaa ctttccagaa     1560

tctggcccag aaattagggc tcaatttcct gattgtagta gaggttaaga ttgctgtgag     1620

ctttatcaga taagagaccg agagaagtaa gctgggtctt gttattcctt gggtgttggt     1680

ggaataagca gtggaatttg aacaaggaag aggagaaaag ggaattttgt ctttatgggg     1740

tggggtgatt ttctcctagg gttatgtcca gttggggttt ttaaggcagc acagactgcc     1800

aagtactgtt ttttttaacc gactgaaatc actttgggat attttttcct gcaacactgg     1860

aaagttttag ttttttaaga agtactcatg cagatatata tatatatatt tttcccagtc     1920

ctttttttaa gagacggtct ttattgggtc tgcacctcca tccttgatct tgttagcaat     1980

gctgtttttg ctgttagtcg ggttagagtt ggctctacgc gaggtttgtt aataaaagtt     2040

tgttaaaagt ttaaaaaaaa aaaaaaaaaa                                      2070


<210>  494
<211>  8513
<212>  DNA
<213>  homo sapiens

<400>  494
ggcggcggcg gcggcggagc caggacccag acatctggga ctgttgttct ctcgcggcgc       60

gaccgcctca gtcacttcgc ccagagaccc ggacctggtc cgctggggag caggcggcca      120

taaaccccct ctctcccggt tccctgacgc cgcggcagga gctgttacaa acaccctgcg      180

gttggtctcc gatgcccttc agtgaggtgg ggacgcctgg accctggtga gcgaacccca      240

agccaccccc caccccaact cagtgtcttc gccggccccc ggcccgtacg cctgtctggt      300

cgccatggct gaaaacacag agggggatct gaactccaac ctgctccacg ccccctacca      360

caccggggac cctcagctgg acacggccat cgggcagtgg ctccgctggg ataagaatcc      420

caaaacaaaa gagcagattg aaaacctgtt acggaatggg atgaacaagg agctgcgaga      480

tcgtctttgt tgccgaatga cttttgggac tgcaggactt cgttctgcca tgggggcagg      540

gttttgctat attaatgacc ttacagtaat acagtcaaca caggggatgt acaaatacct      600

tgagagatgt ttctcagact tcaagcagag aggctttgtg gttgggtatg acactcgggg      660

tcaagtaact agcagctgca gcagccagag gcttgctaaa ctcactgctg cagtcttgct      720

ggccaaagat gttcctgtgt accttttttc aagatatgtt cctacacctt ttgtaccata      780

tgcagttcag aagctcaaag cagttgcagg tgtgatgatt actgcctctc acaaccgcaa      840

ggaagacaat ggatacaagg tttactggga aactggtgct cagatcacat ctcctcatga      900

taaagaaatt ctaaaatgta tagaagaatg tgtggaaccc tggaatggtt cctggaatga      960

taatttagtg gataccagcc cgctgaagag agaccctctg caggacattt gcaggagata     1020

catggaagat ctgaaaaaga tctgttttta cagggagtta aactcgaaga ccaccttgaa     1080

atttgtgcac acatcttttc atggggtcgg acatgactat gtgcagttgg cttttaaagt     1140

gtttggtttt aagcctccaa ttccagtacc agaacaaaaa gatcctgatc cagacttttc     1200

taccgttaaa tgtccaaatc ctgaagaagg agaatctgtg ctggaacttt ccttgagact     1260

ggcagagaaa gaaaatgccc gggtagtgct agccacagat cctgatgcag acagactggc     1320

agcagcagaa cttcaggaga atggttgttg gaaagttttc acagggaatg agttggcagc     1380

tttgtttgga tggtggatgt ttgattgctg gaagaaaaat aaatcaagaa atgctgatgt     1440

gaagaacgtt tatatgttag ccaccacagt ctcttctaaa attctgaagg caattgcact     1500

taaagaagga tttcattttg aagaaacatt accaggtttt aaatggattg gaagtaggat     1560

aatagacctc ctggaaaatg ggaaagaagt cctttttgca tttgaagagt ctattggttt     1620

tctctgtgga acttcagttt tggataaaga tggggtgagt gcagctgttg tggttgctga     1680

gatggcatct tacctggaaa ccatgaatat aacattgaaa cagcaactgg ttaaggttta     1740

tgaaaaatat ggttatcata tttcaaaaac ttcctatttc ttgtgttatg aaccacctac     1800

catcaaaagt atatttgaaa ggcttcgtaa ttttgattct ccaaaagaat atccaaaatt     1860

ttgtggaaca tttgctatat tgcatgtacg ggacgttacc actggatatg acagtagcca     1920

gcctaataag aaatcagtgc tgcctgtgag taaaaacagc caaatgatta catttacttt     1980

tcaaaatggc tgtgttgcta cccttcggac aagtggaaca gaaccaaaga taaagtatta     2040

tgcagagatg tgtgcgtcac ctgaccagag tgacactgct ttactggagg aagaactgaa     2100

gaaactcatt gatgctctga tagagaattt tcttcagcct agtaagaatg gactgatctg     2160

gcgttctgtt taggggtaca ccaatatgtc atgacactgt gtgggcatat ggaacagagc     2220

aaccgagaac tgcatacatt gaaccttgtg ttagcattct ctctctatct catctggccg     2280

agtatctttt tccttttatt ttctttcttt ttggtcaact ggctagacta aacaaagtat     2340

aagtttgaaa tgaaatggtc tagagggaaa tgattcaaat tttttcataa ttcaaacaaa     2400

agttattaca ctaaaagtat tatagtaacg tattgtcctt ccgttaacag aaacatcaca     2460

attcaaaagt gagttttctt attatagtgt gattaagcct agttctgtat ctcgtaattg     2520

tgtatagcat ggtaaaagaa aaaaaaaaag acaggtaaat gttatataat tgtagggtta     2580

gttaaggaaa ttagtccata aaattggcaa gaaaatggta ctttccttga ttgttatgaa     2640

aaagtgtcat tgtgacatca caggtattaa tttacaaatt agagtatttg aaataggata     2700

tttagcattt ctgtagttta gaacagatgt tacagtgtgt ggttttggca tgtctgtttc     2760

aggtgccctt ggtgcagtat aaatttactg tatgtattta aaattctgat gtttactgaa     2820

cataaaacaa tagtggcaac actcctattg gctttgttct tatcaaattt ctcagtgcct     2880

tctcagggtc tggtgtgaac agaaaaaaca gtgttcctgc atttaccata atttaatcag     2940

tcaatttgca gatagctaag gaaaatcttc caaaatctgt aggtgcttcc tctatatcaa     3000

gtgagtttgc tgattttaaa atcttaggaa tataaataaa gatcttaata aaagcaagct     3060

taatgtagtt aaggatcttc atattagaat tgtgtcattt atcaaacctt ttattacaga     3120

aaaaaatctg aactgagaaa ggagctctga atttatttga cagtctaact tttgaattac     3180

atttttgtaa gtagatttat tcttttattt tatgaagtaa tgttaatttt actaagaata     3240

aaacatccaa attttaagta ttatgaaata ctaaaactac atgttttaaa acagaggtcc     3300

agtttattct aacatcttgc tgacttctgt agaatttctg attgcatgac tattatttat     3360

cttcttttag tgtagaaaat aattttttac aaaaagtcac ttttgggctg ggcgcagtgg     3420

ctcacgcctg taatcccagc actttgggag gctgaggcag gtggatcaca atgtcaggag     3480

tttgagacta gcctggccaa tatggtgaaa ccctgtctct actaaaaata caaaaattag     3540

ccgggtgtgg tggtgggcac ctgtagtccc agctactcgg gaggctgagg caggagaatt     3600

gcttgaacct aggaggctga gattgcagtg agccgaaatc acgccactac actccagcct     3660

gggcaacaga gggagactcc atctcaaaaa aaaaaaaagt cacttttggc taatcatgca     3720

gtcttctgaa aaggtttaat agagaaatgc tgtttaggct gggcttggtg gctcacatct     3780

gtaataccag cgctttggga ggctgaggca ggaggattgc ttgaggccag gagtttaagt     3840

tacagaacta tgatcacact gccgcactga agcctggatg acagagtgag accttatctc     3900

aaaaaaaaaa aaaaaaagag agagagagag aaaaagaaat gctgtgttta atcttcttaa     3960

aatgtatctt gtcctacata gttctcagaa tacatatggg gtatagttag gagataacaa     4020

taacaagacc taaacaaatt gcttatggga gatagcactg taattagaga atttatttca     4080

tataaaataa taatataaag tttgaactga ttagaatgtt ccttaaatca tggtttcgtt     4140

tgttgcagct gtcagctaac atttggttga gctcatataa tccaaaccta attgtccaac     4200

tattgtattg ccactattgt taatttgttc cttccttact ttcttattgt tggatcttat     4260

atgactgtat gactgtagat aatagacagc tagctaaatg tagagcacca tttttctcaa     4320

tgagtttgtt ttcaaaggct ttgcactgga gaagatatgt gtagaatttt tgttttattt     4380

ttaaaatgtg taaaacatct tttgttttat atgcttttaa gaatgtagat tgtaatttag     4440

gaaatggcat atattctgca aagtggtata atgttgtata tatgaaaaac aggtatattt     4500

ggtttagttc tgtgtttcag tgactgataa acaaaaatga agctaaaatg aatcaacggc     4560

tcattcatag ttactaaagc catgtcatga ctgtcattct attatgaaga aaacagtttt     4620

atttgagtgc tttaatataa tgcaacattt aagtcatctt aaggtgaaaa gttattgaag     4680

tgttcttctc tcaagttaac aaaattttac aaatgttcct gaagtgtatc gattgaggga     4740

attattttat tctagcctgt catgagtctg tctgagcatg atacttaaca tgaacttgat     4800

gtagtaggtg cacatttgcc taacaggata aattcagtga tagcccaagc tggtcaggag     4860

agacagaagt gctggctagg aggtctcagc ctcgggcact acaatgttta tctttttctt     4920

tttgaacaat attgtgaaaa tgattgcatt ctcattgagc atgaaagtca aaactggaat     4980

tttctaaagc tttggagaaa aggagagaat tagtagggca agatcaaagc atacattgga     5040

aataaacagt agaaataagc aaacaatata aagagacacg ggaaatgctt ctcgtgaagg     5100

gcaaatgtaa caccataaca gtagggaata aactgtgtcc cacctgttta cttgtgttta     5160

tttgttgtta tgatgagtat gcacctacca ttttccttta ttgtgatcac taaaatgagg     5220

ccaaggttta ggaggtgaga aaaagtatcc cttttacgga ttcagttcct gctaggatgt     5280

tgtatcagaa tcatgtgaga actcaggaag aggtagagca gaaataaaaa ggaagaaaat     5340

gtagattaga aaataagact tctgagaaaa agttcaagga ataaagattg tttgactctg     5400

gagaggagaa agctgttgag atagtttgct aagtttgcta ataaagcttt attgagtctt     5460

ttattgaagg gttcaaagta agaaatacta tgccatagtg ttctccatct ctagtgaaga     5520

cagaaccaga gggaataagg atcttttttt taaagacagc atggaaagtt taagatttag     5580

gaacttcttg agaaatcttc ataatatctt ctattcaaaa tctttttttt atttttaagg     5640

gaataaaaat tttaaaaatt aagagatata cagatgactt tttaagggtc cttctttcca     5700

gcacattttt tttaaaaact caggttagaa caaaaatgtc ataaagggca ctaaaagtaa     5760

catttgggtt tcactccata tctagaagaa tttagctcac aaaacaattt ttgtgtgttt     5820

tgagtaactg atgcataagt gcaatgaata attttcctgc ttcactgtta tttttaattt     5880

aacctggcaa attaagtgag acttgaacaa aattttgttc atcttgaaga atgtatagtg     5940

gcttaggtta tttgaggttt tcgttttgaa tatatatgtt gttattttga tgtagatacg     6000

ttagcagatg gagaggttct aagagattgg atactttgga atgtctttat ataggaaata     6060

gacctcccat ttcttaagca agttgcttct ggaattgatg caacagggat attagctgta     6120

gtttaatgga taagttgttc tatgagctgc tgctatcagt acttttttcc acattttcca     6180

ttgatatttg tgatgcttga aaaatccaaa cttcacttgg atacatttaa ttttatgcct     6240

ttttctctct acctcccact tttcctaggc acccttgcac attttgttac tgtgaaggac     6300

tattgccctg ttacctcact gataagaaat ctcaactgta ttcattcaga atgctttaag     6360

cttagtcata aactacattt gcctatggac ctttggttat tttgttaatg ttgtcattat     6420

atttaagact tattgtagga agtaatttta aatctatttc ataacctgtt ttgatctgtc     6480

tgcatactgc tatatgttaa tttattacgg ccttttacaa ttcacttgtc atctgagatt     6540

gttctagaaa ctgatgagga aagagtcgta ctaaccaaaa tgaatgggca attgacataa     6600

cattctattt caggtttcct tgtacttggg gagccaaagc acaagatcta aggaaatctt     6660

attcacattt gtccctcaga gcatcttacc ctaagccata gaggtataaa tagtaagatg     6720

agaattgctc attgtctgac tccttgcaca gcatgaattt aattctagtt ggaaacaaag     6780

ttagtgttga ctactggtta ccttaaagta ttcaccatac tatatattta ttagaccatc     6840

tttcctcttt gtttattcaa gactatgtac ttataaaaga gaacctataa gaatgtgtag     6900

agtgaccaaa tagggacaaa gtgacatacc tagagtttgc tgctcaaatt tttccactag     6960

cgtaacccta aagcagaggg gcatgatgaa gggggaaggg gttctgagag caaaatcaga     7020

atcagcctac cactgacatg aagtgtgttc tgtctttaaa atgtaagtga attttgcatt     7080

ctttataata aaacttttaa tataaaaatg atatgtttaa tctttactga aacttatgcc     7140

accacaaagg agcaccatgt tcatcacgtg gctgctcagt tttctccccc agtgccctca     7200

cccccagtgg aggcaagtcc ttgagctaca cacactggct gtagtgcaag atatataaac     7260

ataggccggg ctcggtggct catgcctgta atcctagcac tttgggaggc cgaagcaggt     7320

ggatcatctg aggtcgggag attgagacta gcctgaccga catggagaaa ccctgtgtcc     7380

actaaaaata caaaattagc cgggtgtggt ggcacatgcc tgtaatccca gctactcggg     7440

aggctgaggc aggagaatca cttgaaccca ggaggtggag gttgtggtga gccaagatcg     7500

cgccgttgca ctccagcctg ggcaacaaga gtgaaactcc atctcaaaaa aaaaaaaaaa     7560

agatatataa acatagaaca tatccagact atttcctgcc cttggaatct gaccttcaga     7620

aggattaatg ccaaactaaa ctgacctgaa acagttttgt tactattggc attccttgac     7680

taaaaaggac cacctgatgc tcagtcccga gagtaggaat cgtggtttat tatttttcat     7740

atccatacca cctagttcag tacctgttat agagtgttta attgctgata ctaggaatta     7800

agggattttt taaaagtagc aaatagttta aggaacaatc aaaaaatgaa ttttctaatt     7860

cagttttttc aatgaagtcc catcactgaa ctttataatg taatgtttat taagcagaca     7920

tccccttaaa tactcagttt ctttggagag agcaaagcat atctctctgt ggaaattata     7980

tataatgcct ggtattttac actcaaagca aggtgttggc caggaaggta aagaaatggt     8040

gtctatgtag acttaatatc actagtctaa gtgtcatttt gagcctagta gcactacctt     8100

ccaagtgagt cacaacaaat ttgatcctat ttggtatgtt tttgtccact gttatgattc     8160

atcatgtatc ttacaagagc cactcaagca agactctgct tctatgtatg gtgaggcctt     8220

gttgttctag gctagaataa actctttgta tgcctcattg aatatgccag gtaaaattta     8280

tgcagtcaag aatgaattat ttttctgact aaagtgtgta gcagtagttc aaaattgtgc     8340

ccttgtttta acagtttctg tcaacatctt ctcatttttc cctacaaaaa caccagggtg     8400

tattataagt actgcctgtg agaatttgca ctttatgtat ttgtgtgtgg atttcttgtg     8460

gttttagcca aatgaagtgt tatcagtaat aaacaggtct cttcataggc atg            8513


<210>  495
<211>  9642
<212>  DNA
<213>  homo sapiens

<400>  495
atccgctggg caggatccgc cgcgccggct gcggccggcc gggctgggag acccgcgcgg       60

ggtagaaggt gaggggaccc ggcgggccgc tcggcacagg ccgggacatg aacgcctgga      120

agtctggctg ggagcggacc catgatcgaa ggaccaaagg agccgcttga tcgctggacc      180

tggccctgcg accccagtca tgggccagac ctcggtgtcc acgctgtccc cgcagcccgg      240

cagcgttgac ggactggaca aagcttctat agcaaactca gatggcccca cagcaggttc      300

ccaaacacct cccttcaaaa gaaaggggaa actatccacc attggtaaaa tctttaagcc      360

ttggaaatgg aggaaaaaga agaccagcga caaatttaga gaaacctcgg cagtattaga      420

aaggaagata tccacacgac aaagtagaga ggagctgata agaaggggag tgcttaagga      480

attgcctgat caagatggag atgtaacagt taactttgaa aattcaaacg ggcacatgat      540

acccatcgga gaggaatcta cccgagagga aaatgtagta aagtctgaag aaggtaatgg      600

ctctgtatct gaaaaaacac cacctctgga ggaacaggca gaagataaga aagagaacac      660

tgaaaaccac tctgaaacac cggcagctcc tgctctacct ccttctgctc ctcctaagcc      720

tagacccaaa cctaaaccca aaaaatcacc tgtgcctccg aaaggggcca ctgctggggc      780

cagccacaaa ggtgatgaag tgcctcccat taaaaaaaat accaaggctc ctggtaagca      840

ggcccccgtc cctccaccca agccagcaag ccgaaacacg acccgagagg ctgctggctc      900

ctctcattca aaaaaaacaa ctggctctaa agcatcagct tcgccatcca cttcatccac      960

ctcatctcgt cccaaagctt caaaggagac agtttctagc aaagcaggga cagtggggac     1020

caccaagggc aagagaaaaa ctgacaagca gccaataact tctcacctgt cctcagacac     1080

aacaacttct ggcacatccg acctgaaagg agagcctgca gagaccagag tggagagttt     1140

caaactcgaa cagactgtcc ctggagctga ggagcagaac acaggcaaat tcaagtccat     1200

ggtccctcca ccccctgtgg ctccagcacc ttctcctctg gccccccctc tccctcttga     1260

ggatcagtgc attactgcct cagacactcc agttgtcctc gtcagcgttg gagctgacct     1320

gcccgtctct gccttagacc caagtcagct tctttgggct gaagagccga cgaacagaac     1380

cactctctac tcaggcactg gcttaagtgt taacagagaa aatgcaaaat gtttcacaac     1440

caaagaggag ctggggaaga cagtgcctca gctactgact cctgggctga tgggcgaatc     1500

ttcagaatcc tttagtgcct cagaagatga aggccacagg gaataccaag ccaatgactc     1560

tgactcggac gggcctatct tgtacaccga tgatgaggac gaagacgaag atgaggatgg     1620

cagtggagaa agtgctttgg caagtaaaat acgccggagg gatactcttg ctatcaaact     1680

tggcaacaga ccatctaaga aagaactaga ggacaaaaac atcttgcagc gtacatctga     1740

agaagagagg caggaaatcc gacaacaaat tggaaccaag ttagtcagga ggctgagcca     1800

gaggcccaca actgaagaat tagagcaaag aaacatccta aaacaaaaga atgaagaaga     1860

ggaacaagaa gcaaaaatgg aacttaaacg cagactcagc agaaagctca gcctgagacc     1920

cacagtggca gagctacaag ctcgaaggat cctgcgattt aacgagtatg tagaagtcac     1980

ggattctcct gactatgacc gccgagcaga caagccctgg gccaggttaa cacctgcaga     2040

caaggcagca ataaggaaag aactaaatga atttaaaagc acagaaatgg aagttcatga     2100

agagagtcga cagtttacaa ggtttcatcg tccataacga agagtgagac tatttggaaa     2160

cagagactga tcatctttgg gggaagccct gcttcctgaa aacctgatat tgcactggga     2220

tttgaatgtg tgtgtttccg tttaacttgt ggtgaaggaa gtgtgtgact cagcttggct     2280

gggaagtgct cctcacctgt gtggcccaga tggctccaac aagcaaaagg aaggatgcag     2340

tgactcttgc tgcccagaat gcacagcgat ggtaagagac accgtggata ttcttcatca     2400

gaagctttaa tcaaagaaga tgagcagaag acaatcactg gctccctgtt accagaaagc     2460

caaattttat aatgcgggtg aaagaaaaat atagattaaa attgctgggc actgaaaagg     2520

ggtgggagtt ggaaatcaga aagaaagaga aatatttcat tatgttaatg aagaaaagag     2580

aaaattgaag cataaatgta tttttgaagt agttattcgg tagctgagaa cttattaagg     2640

gatttaggaa tttaacctcc tgatgtggat tcctcaaaga cttgatcgga gaatactctt     2700

gtttcaccat tatgttggta cagtatagta ccattatttt atgttgtgcc agtgaatcca     2760

gttgccagaa ataagtctga atgttttcat gcatcttttt cttaaatgca agagcttcta     2820

ctgactctta acaagcatgc ttacccaaat tttgttgcat gcttttaagt agcattagct     2880

atgcacactt gacattttta aatatccctt tcctagtgta ccagccttca caggataaga     2940

ggactgggaa taaagtcaga tgtaatgtga ccctagaaaa ctgtagcaag cttcagaaat     3000

aaatcttttg atctttccct atcttgatta gatccaaagt caaagcaacc atacttcacc     3060

tagagaagac agtattggca atcatgacac ctgtaataaa aacttgaatc caaagtcaaa     3120

acttaagcaa gatacaaatg tgctgcctgc agttagtcct gcatgggaat aaggactagt     3180

tattttttta gtgctgcatt tttttaaagt tggattgctg ctatttaaaa aaaaaaaaag     3240

gacacagatc aaaaaaacac ccaaaggctt aacagaacat ggaaagttcc cactaagttg     3300

tgtgtgagga aatcctcatc ttgtatttta agaatctgca gatggcatcc atagatacag     3360

tacagtattt actgtcaatg caaaagaatc agtgaggtta aagtagtgga agttttccct     3420

atgagcctac agtctgtatt gtttacatta agaaactctc tattattgtg ttgctatttt     3480

ccatggagtc acaggcacac tatgacttct gctcccaaat acatatgacc atatgtaaat     3540

accaccttgc atttcattgt tcttcacaag tgctttgtgc ccctttaatt aaaaacacat     3600

gaaatgaata acaaaacaag acccaaatag agtttatttt attctcagag tttggactac     3660

aattttctaa gatgtttctg gttcaagact gtcattttct atttcaaccg aaaagtaagc     3720

atttaacccg gtgaataaat gtagatcctg ccattcattg gtattttaaa gaaccacttg     3780

aaatcggatc attttattta aaaataaaaa atgttaatgc cagttggcct actataaaaa     3840

gccaggacca tgttagaatt aggaaaagta accagcatta ctgcacctct tgttagactc     3900

tgtgcattaa taaaacacac ctagagtctg ttgtcatttc actaatagga taagacaaat     3960

tttttgcttt gaaaaaattt ttctgcatgc ccaggtgtct gtctctggct gaggttttgt     4020

ctattttaca gtgtttcaat ccagccataa aaattaactt gtgatttttt ttttcccaaa     4080

gtcatgcttt tccttaatta tatttttatt ttattatttt agtgtcttga gaaaaatacc     4140

aagagatata atgtttcttt taattgtcta tgcttaatca tctttaaaca ctttttaaat     4200

ttctaaccac aagacctctc tataatggta aatgtaagac atcaccattt tatcactcaa     4260

agtatgttat tgaaagtttc tatttggttg ataaaaggaa caattttttc ccacttttga     4320

tgcctgtgat gcaatttttt attgcctaca atgagataca cttagtacaa aaaatgaaaa     4380

tctggtattt caaaattgca tttcttgtat aataggtcag atttattaac tactcatact     4440

ttttctttac actaatcgat acatttagaa aaaattttct aagttagaga caagtttaaa     4500

agtaaaaaaa aaaaaaaatt agccactgct agtctactgt ttaggtaatc ggaatcacca     4560

attattttat tagaatgatg gcttgagtaa aaagctgtgg aaagaattaa aggattatga     4620

gctaagctgt attttgcaga atatggttct attttagtag agcagagatg agacatatcc     4680

ccaccggcca cccagccaga ggtctcctac ctgggggccc taaagggatg cagaggtctg     4740

gcccaccctc cgtgcatagg cacctctgtc caccaccagc gtttcagcaa tccaaccagt     4800

aagcatatgc tgtataggaa aaataaaagt gtgtgggaat tggatttctt ttgttgtaac     4860

acaattccag gtttttggct atttaaagtt tgacattagg ctgacatcga ggaagtaagt     4920

gggttttcct gagttcccaa gatatgatta aggaagaaaa caaacccatc tccaggaaga     4980

tcccaggcag gaaagaacta gacagatgta gaaaccaaag tgaccatttt agttttttta     5040

ttggagaata aaacattaat attagggtat taagaagatg ctcagcaagc ttgatcagaa     5100

tcttcatggt cattaccaat cagtctgaca aaatagttct ctggtagtca gcattcattt     5160

aaggcagctt gcctgataat ttcctgtgtt atgtgaagtg tcttgcactt tcacatgtta     5220

gctataattc cttaaattac ttaactgaaa tctgtaatag agaaccattt tggcatttga     5280

acagctattt tacatggaga aaaagcaaac acatctgttt gctttaccca gaaaaactga     5340

ctttctggtt tcatcttcat attgtttagt agcataatga gagtagtcct ttatctttct     5400

ctaatgttag taaatatatt ctgttagtag gaagttctga aattgaaggg aaaatatatt     5460

taaggaaata aaggaattca atacaccctt caaaagtcac caaatactga aaataagaga     5520

tgagtcctta aaacctgagt caaaaaaggt ccagttttac agcctgcaat taattcaggg     5580

ctgcgttggc attaaaaaag aaaatatata tatatatata tatatatata tatatatata     5640

tatatatgta tattatatat acagtagctt acacttaaaa gaggaaaaat ttgcattaac     5700

attgcatatt ctgatatgta ccatattaac acataacagg cattttattt atgcttcata     5760

gaatcagaca gacacaactt tcaaaaatct tactgtattc acaatagaaa agggtagtct     5820

tgtctaccac agaggagtat gtccacactt aataatgaaa actttcttcc tttcctgccc     5880

aaaaatttct tcagtctgtt attattttta agtgcccctt gctgcaaatt tcaaacagag     5940

caagaaatct tcctcagagt aggtggtatg aaattaaact agtacaatat atatgaattc     6000

atgtcattta cccctgagta tggtagaatt gttaaagcat tcttaaattc caattatatg     6060

aagcctatca ttactaggaa aagtatattc tttgggataa gaattaattt cttcacacta     6120

ttagagcatg ttgtgagtag taaggaacta cttagatgca atttatttac agaattgtcc     6180

cttgacctct tgaaatggct agatctttca ctactgtgta ggtagtctct acttactggt     6240

aggatagatt acattgcttt actggacaaa gcagaatgaa cttatataac taaaatatgt     6300

cctatattgg ctgggtgcgg tggcttacac ctgtaatacc agcactttgg gaggccaagg     6360

tgggtggatc agttgaggtc aggagttcga gaccagcctg gccaacatgg tgaaaccctg     6420

tctctactga aaatacaaaa aaaaaaaagt atctgggcat ggtggcttgt gcctgtaatc     6480

ccagctactt gggaggctga ggcagggaaa tcgcttaaac ccgggaggtg gaggttgcag     6540

tgggcccaga tcgtgccact ccactccagc ctgggagaca gagcaagact ccatctcaaa     6600

ataataataa tagtaataat gaataaaata aaataaaata tgtcctccag ggaaaagcaa     6660

tgacagagta atcaccaaat taataggaac atctttctag agaaagtaca tgcccagtta     6720

gttcaaaccc aggtttcaaa gaagtagcac tgggctctac tgtaaaggca ggcagtgacc     6780

aagaggtggt ggggagagag gtagagtacc ctcaaatcat tcccattttc acttccaatt     6840

tcccttttgt aatcattaag cttaagctat gtatggaaat gcaaagcacc attagcattt     6900

ctagaaagca gctggaacct tacccaccaa tgcttttttg aagacagtat catcccaaat     6960

ttaaaaatcc tattgtatat gttgtaaaat ttctggcaaa gaaatggagg atcctgtggc     7020

agctattccc acctaaagcc aaccctataa ggatgggtca ttttttagcc atgctaggat     7080

ttactgcaca cacaaaaaat gtcatttagc ttgtcacatt gctagcacag ctgcacatat     7140

gagcaaagca ctgttggtct gtgtttctca gtgggggtac tcttggcatt tggagctgga     7200

taggtctttg ctgtacagaa tcatcccatg cattgccaga tgtttaatat cccaggcccc     7260

tgctgactaa atgtcagtag cattctcagt cattgtaaac accaagaata aaaagcattc     7320

ccccaggttc aaatgccctc cctgggaggt tggtatcacc tcccctgaat gccactgtct     7380

actgcatttt gaggacacag ggagaaaaag tgcctatcct caaacattgt ctctgctgcc     7440

ttgcatttct ttgggccctg aatggttttt ctcccttcat ttttcgagcc tttctctcag     7500

tgcagctgtt cttcagggag gaggttactg ggcagccttg gccattcagt gggcatgggg     7560

acttggccta gtccctatat atatatactt aaagtcccta tatatactta aaggagagat     7620

catacatgaa gaaagctttt tttttttttt ttttttttgc cttacaactt ttctttagaa     7680

ccacattatt ggtcataatc cttgttactg tcatgaggat tgttgcatgg gttaaacaca     7740

aacacagact agcaatgcac ttgaacaaac ctggtggtct ttggaaataa atcaccatta     7800

gatttcacct ggttatgctg catcccataa gttccaaatg aatcacctgc ttatcctatt     7860

aacgaagcat ttaattcaca cacaaatgct tgaatttccc ctgtataaat gtagtcatgc     7920

gattcaactt ttctaataag atttgtgaat gctgcatcat gatgaaaatg tggattaact     7980

gtgggttgca tgcctgttgt tcatacttca gtgatggtca cacacaaaac aagatgagtt     8040

ttacttaggt gaaacattat taaactgtac taacaataca gaaacatatt ctctttgtcg     8100

ctttttatca ccaaaactga atggcaaata tgtcttgaca ttacttggat gaactgtggc     8160

tagcaaaatg gaattaactt agccactata attttttaaa acattaaagt ttctaaattg     8220

tttttggggc cgagtaacgc agagtcaata aaggtggtta tattgtaagc ttttagatgg     8280

tgcttaagaa ttcttatctt tttaaatagc agtatttttt ttttaagaat aaattgtaag     8340

gagcaaataa ggcagaatgc cactctaccc tcaggtcaat tttatggtat atgaaaatgc     8400

cagtaatatt tgtgccactt gccaactcgg gggaggaggg gcttttccct tactggatac     8460

ttttgttata gtttgactat gtcattatgt tgtttagaga gcctccacaa tgagaagttg     8520

ccactgcagg gctaactcgc cttcagaaat aatcagaatg attcaagggt caaaccactt     8580

tcatccctta aaatataggg actaatattt ctttttcttt tttttaaaaa aaacatttct     8640

tctgtggctt agaaatgtgc cagtgtgttc aaaacattta caccaatttc accagattta     8700

ggacctatta aaaattcaaa caagtttctt tttttttttt ttttttctgt gtaacaggga     8760

tttttaaata acggactata tgcattcttt tgttatttca cacttcagtt aaagtgataa     8820

caatggtaaa ctgtgatcat tatcagactg actgaatgct ttctgatttc cagtgagtga     8880

tctagttcta cgtattacac aggtgtaata tctgtgagtg taaataactg gaactgtaca     8940

ctgattaaca tgacagtttc tcttttgttg ttcttatctg tactgtatta tagtatgtgg     9000

gtataaatat ctacaagtat acacacatat gtacttgtat tccactattg taacctgaaa     9060

gaaagactat gtattccctt ttttaattcc gtactggtat ttgtgttatt taaaaagcaa     9120

aattctgctc tatttagttg tataatatta gaggatactt tgctgtgcac aattccaagt     9180

gccttagaac attgtttagc tttcctaagt atatataaat gcatatatgt ataaaattgg     9240

gaaaagttac ctcaataaaa tcattgggaa atccccagtt ttagtttgtt ccagtttctc     9300

ttatatttgg atagtgctca gcctttttaa atgaaaaaag aaaaaagagt aagacaactt     9360

ccctaattgc ctgttatttc agcttcacct aagtttttaa cacctctttg tatgtaaggt     9420

cttgagacat gtaaggcctg gtacttttta tttaaaatgt ctgtctaaag aattactgct     9480

cttaaaagaa acttccagta ttttttttaa cttgctatct ttttatgtct gaggtatttg     9540

atattgatgt ttttattgcc attattatat gtaaacataa aagatagtcc atttagagtt     9600

tataatatag aaaataaaca gacttcctca ttaaaaaaaa aa                        9642


<210>  496
<211>  9402
<212>  DNA
<213>  homo sapiens

<400>  496
atccgctggg caggatccgc cgcgccggct gcggccggcc gggctgggag acccgcgcgg       60

ggtagaaggt gaggggaccc ggcgggccgc tcggcacagg ccgggacatg aacgcctgga      120

agtctggctg ggagcggacc catgatcgaa ggaccaaagg agccgcttga tcgctggacc      180

tggccctgcg accccagtca tgggccagac ctcggtgtcc acgctgtccc cgcagcccgg      240

cagcgttgac ggactggaca aagcttctat agcaaactca gatggcccca cagcaggttc      300

ccaaacacct cccttcaaaa gaaaggggaa actatccacc attggtaaaa tctttaagcc      360

ttggaaatgg aggaaaaaga agaccagcga caaatttaga gaaacctcgg cagtattaga      420

aaggaagata tccacacgac aaagtagaga ggagctgata agaaggggag tgcttaagga      480

attgcctgat caagatggag atgtaacagt taactttgaa aattcaaacg ggcacatgat      540

acccatcgga gaggaatcta cccgagagga aaatgtagta aagtctgaag aaggtaatgg      600

ctctgtatct gaaaaaacac cacctctgga ggaacaggca gaagataaga aagctggctc      660

ctctcattca aaaaaaacaa ctggctctaa agcatcagct tcgccatcca cttcatccac      720

ctcatctcgt cccaaagctt caaaggagac agtttctagc aaagcaggga cagtggggac      780

caccaagggc aagagaaaaa ctgacaagca gccaataact tctcacctgt cctcagacac      840

aacaacttct ggcacatccg acctgaaagg agagcctgca gagaccagag tggagagttt      900

caaactcgaa cagactgtcc ctggagctga ggagcagaac acaggcaaat tcaagtccat      960

ggtccctcca ccccctgtgg ctccagcacc ttctcctctg gccccccctc tccctcttga     1020

ggatcagtgc attactgcct cagacactcc agttgtcctc gtcagcgttg gagctgacct     1080

gcccgtctct gccttagacc caagtcagct tctttgggct gaagagccga cgaacagaac     1140

cactctctac tcaggcactg gcttaagtgt taacagagaa aatgcaaaat gtttcacaac     1200

caaagaggag ctggggaaga cagtgcctca gctactgact cctgggctga tgggcgaatc     1260

ttcagaatcc tttagtgcct cagaagatga aggccacagg gaataccaag ccaatgactc     1320

tgactcggac gggcctatct tgtacaccga tgatgaggac gaagacgaag atgaggatgg     1380

cagtggagaa agtgctttgg caagtaaaat acgccggagg gatactcttg ctatcaaact     1440

tggcaacaga ccatctaaga aagaactaga ggacaaaaac atcttgcagc gtacatctga     1500

agaagagagg caggaaatcc gacaacaaat tggaaccaag ttagtcagga ggctgagcca     1560

gaggcccaca actgaagaat tagagcaaag aaacatccta aaacaaaaga atgaagaaga     1620

ggaacaagaa gcaaaaatgg aacttaaacg cagactcagc agaaagctca gcctgagacc     1680

cacagtggca gagctacaag ctcgaaggat cctgcgattt aacgagtatg tagaagtcac     1740

ggattctcct gactatgacc gccgagcaga caagccctgg gccaggttaa cacctgcaga     1800

caaggcagca ataaggaaag aactaaatga atttaaaagc acagaaatgg aagttcatga     1860

agagagtcga cagtttacaa ggtttcatcg tccataacga agagtgagac tatttggaaa     1920

cagagactga tcatctttgg gggaagccct gcttcctgaa aacctgatat tgcactggga     1980

tttgaatgtg tgtgtttccg tttaacttgt ggtgaaggaa gtgtgtgact cagcttggct     2040

gggaagtgct cctcacctgt gtggcccaga tggctccaac aagcaaaagg aaggatgcag     2100

tgactcttgc tgcccagaat gcacagcgat ggtaagagac accgtggata ttcttcatca     2160

gaagctttaa tcaaagaaga tgagcagaag acaatcactg gctccctgtt accagaaagc     2220

caaattttat aatgcgggtg aaagaaaaat atagattaaa attgctgggc actgaaaagg     2280

ggtgggagtt ggaaatcaga aagaaagaga aatatttcat tatgttaatg aagaaaagag     2340

aaaattgaag cataaatgta tttttgaagt agttattcgg tagctgagaa cttattaagg     2400

gatttaggaa tttaacctcc tgatgtggat tcctcaaaga cttgatcgga gaatactctt     2460

gtttcaccat tatgttggta cagtatagta ccattatttt atgttgtgcc agtgaatcca     2520

gttgccagaa ataagtctga atgttttcat gcatcttttt cttaaatgca agagcttcta     2580

ctgactctta acaagcatgc ttacccaaat tttgttgcat gcttttaagt agcattagct     2640

atgcacactt gacattttta aatatccctt tcctagtgta ccagccttca caggataaga     2700

ggactgggaa taaagtcaga tgtaatgtga ccctagaaaa ctgtagcaag cttcagaaat     2760

aaatcttttg atctttccct atcttgatta gatccaaagt caaagcaacc atacttcacc     2820

tagagaagac agtattggca atcatgacac ctgtaataaa aacttgaatc caaagtcaaa     2880

acttaagcaa gatacaaatg tgctgcctgc agttagtcct gcatgggaat aaggactagt     2940

tattttttta gtgctgcatt tttttaaagt tggattgctg ctatttaaaa aaaaaaaaag     3000

gacacagatc aaaaaaacac ccaaaggctt aacagaacat ggaaagttcc cactaagttg     3060

tgtgtgagga aatcctcatc ttgtatttta agaatctgca gatggcatcc atagatacag     3120

tacagtattt actgtcaatg caaaagaatc agtgaggtta aagtagtgga agttttccct     3180

atgagcctac agtctgtatt gtttacatta agaaactctc tattattgtg ttgctatttt     3240

ccatggagtc acaggcacac tatgacttct gctcccaaat acatatgacc atatgtaaat     3300

accaccttgc atttcattgt tcttcacaag tgctttgtgc ccctttaatt aaaaacacat     3360

gaaatgaata acaaaacaag acccaaatag agtttatttt attctcagag tttggactac     3420

aattttctaa gatgtttctg gttcaagact gtcattttct atttcaaccg aaaagtaagc     3480

atttaacccg gtgaataaat gtagatcctg ccattcattg gtattttaaa gaaccacttg     3540

aaatcggatc attttattta aaaataaaaa atgttaatgc cagttggcct actataaaaa     3600

gccaggacca tgttagaatt aggaaaagta accagcatta ctgcacctct tgttagactc     3660

tgtgcattaa taaaacacac ctagagtctg ttgtcatttc actaatagga taagacaaat     3720

tttttgcttt gaaaaaattt ttctgcatgc ccaggtgtct gtctctggct gaggttttgt     3780

ctattttaca gtgtttcaat ccagccataa aaattaactt gtgatttttt ttttcccaaa     3840

gtcatgcttt tccttaatta tatttttatt ttattatttt agtgtcttga gaaaaatacc     3900

aagagatata atgtttcttt taattgtcta tgcttaatca tctttaaaca ctttttaaat     3960

ttctaaccac aagacctctc tataatggta aatgtaagac atcaccattt tatcactcaa     4020

agtatgttat tgaaagtttc tatttggttg ataaaaggaa caattttttc ccacttttga     4080

tgcctgtgat gcaatttttt attgcctaca atgagataca cttagtacaa aaaatgaaaa     4140

tctggtattt caaaattgca tttcttgtat aataggtcag atttattaac tactcatact     4200

ttttctttac actaatcgat acatttagaa aaaattttct aagttagaga caagtttaaa     4260

agtaaaaaaa aaaaaaaatt agccactgct agtctactgt ttaggtaatc ggaatcacca     4320

attattttat tagaatgatg gcttgagtaa aaagctgtgg aaagaattaa aggattatga     4380

gctaagctgt attttgcaga atatggttct attttagtag agcagagatg agacatatcc     4440

ccaccggcca cccagccaga ggtctcctac ctgggggccc taaagggatg cagaggtctg     4500

gcccaccctc cgtgcatagg cacctctgtc caccaccagc gtttcagcaa tccaaccagt     4560

aagcatatgc tgtataggaa aaataaaagt gtgtgggaat tggatttctt ttgttgtaac     4620

acaattccag gtttttggct atttaaagtt tgacattagg ctgacatcga ggaagtaagt     4680

gggttttcct gagttcccaa gatatgatta aggaagaaaa caaacccatc tccaggaaga     4740

tcccaggcag gaaagaacta gacagatgta gaaaccaaag tgaccatttt agttttttta     4800

ttggagaata aaacattaat attagggtat taagaagatg ctcagcaagc ttgatcagaa     4860

tcttcatggt cattaccaat cagtctgaca aaatagttct ctggtagtca gcattcattt     4920

aaggcagctt gcctgataat ttcctgtgtt atgtgaagtg tcttgcactt tcacatgtta     4980

gctataattc cttaaattac ttaactgaaa tctgtaatag agaaccattt tggcatttga     5040

acagctattt tacatggaga aaaagcaaac acatctgttt gctttaccca gaaaaactga     5100

ctttctggtt tcatcttcat attgtttagt agcataatga gagtagtcct ttatctttct     5160

ctaatgttag taaatatatt ctgttagtag gaagttctga aattgaaggg aaaatatatt     5220

taaggaaata aaggaattca atacaccctt caaaagtcac caaatactga aaataagaga     5280

tgagtcctta aaacctgagt caaaaaaggt ccagttttac agcctgcaat taattcaggg     5340

ctgcgttggc attaaaaaag aaaatatata tatatatata tatatatata tatatatata     5400

tatatatgta tattatatat acagtagctt acacttaaaa gaggaaaaat ttgcattaac     5460

attgcatatt ctgatatgta ccatattaac acataacagg cattttattt atgcttcata     5520

gaatcagaca gacacaactt tcaaaaatct tactgtattc acaatagaaa agggtagtct     5580

tgtctaccac agaggagtat gtccacactt aataatgaaa actttcttcc tttcctgccc     5640

aaaaatttct tcagtctgtt attattttta agtgcccctt gctgcaaatt tcaaacagag     5700

caagaaatct tcctcagagt aggtggtatg aaattaaact agtacaatat atatgaattc     5760

atgtcattta cccctgagta tggtagaatt gttaaagcat tcttaaattc caattatatg     5820

aagcctatca ttactaggaa aagtatattc tttgggataa gaattaattt cttcacacta     5880

ttagagcatg ttgtgagtag taaggaacta cttagatgca atttatttac agaattgtcc     5940

cttgacctct tgaaatggct agatctttca ctactgtgta ggtagtctct acttactggt     6000

aggatagatt acattgcttt actggacaaa gcagaatgaa cttatataac taaaatatgt     6060

cctatattgg ctgggtgcgg tggcttacac ctgtaatacc agcactttgg gaggccaagg     6120

tgggtggatc agttgaggtc aggagttcga gaccagcctg gccaacatgg tgaaaccctg     6180

tctctactga aaatacaaaa aaaaaaaagt atctgggcat ggtggcttgt gcctgtaatc     6240

ccagctactt gggaggctga ggcagggaaa tcgcttaaac ccgggaggtg gaggttgcag     6300

tgggcccaga tcgtgccact ccactccagc ctgggagaca gagcaagact ccatctcaaa     6360

ataataataa tagtaataat gaataaaata aaataaaata tgtcctccag ggaaaagcaa     6420

tgacagagta atcaccaaat taataggaac atctttctag agaaagtaca tgcccagtta     6480

gttcaaaccc aggtttcaaa gaagtagcac tgggctctac tgtaaaggca ggcagtgacc     6540

aagaggtggt ggggagagag gtagagtacc ctcaaatcat tcccattttc acttccaatt     6600

tcccttttgt aatcattaag cttaagctat gtatggaaat gcaaagcacc attagcattt     6660

ctagaaagca gctggaacct tacccaccaa tgcttttttg aagacagtat catcccaaat     6720

ttaaaaatcc tattgtatat gttgtaaaat ttctggcaaa gaaatggagg atcctgtggc     6780

agctattccc acctaaagcc aaccctataa ggatgggtca ttttttagcc atgctaggat     6840

ttactgcaca cacaaaaaat gtcatttagc ttgtcacatt gctagcacag ctgcacatat     6900

gagcaaagca ctgttggtct gtgtttctca gtgggggtac tcttggcatt tggagctgga     6960

taggtctttg ctgtacagaa tcatcccatg cattgccaga tgtttaatat cccaggcccc     7020

tgctgactaa atgtcagtag cattctcagt cattgtaaac accaagaata aaaagcattc     7080

ccccaggttc aaatgccctc cctgggaggt tggtatcacc tcccctgaat gccactgtct     7140

actgcatttt gaggacacag ggagaaaaag tgcctatcct caaacattgt ctctgctgcc     7200

ttgcatttct ttgggccctg aatggttttt ctcccttcat ttttcgagcc tttctctcag     7260

tgcagctgtt cttcagggag gaggttactg ggcagccttg gccattcagt gggcatgggg     7320

acttggccta gtccctatat atatatactt aaagtcccta tatatactta aaggagagat     7380

catacatgaa gaaagctttt tttttttttt ttttttttgc cttacaactt ttctttagaa     7440

ccacattatt ggtcataatc cttgttactg tcatgaggat tgttgcatgg gttaaacaca     7500

aacacagact agcaatgcac ttgaacaaac ctggtggtct ttggaaataa atcaccatta     7560

gatttcacct ggttatgctg catcccataa gttccaaatg aatcacctgc ttatcctatt     7620

aacgaagcat ttaattcaca cacaaatgct tgaatttccc ctgtataaat gtagtcatgc     7680

gattcaactt ttctaataag atttgtgaat gctgcatcat gatgaaaatg tggattaact     7740

gtgggttgca tgcctgttgt tcatacttca gtgatggtca cacacaaaac aagatgagtt     7800

ttacttaggt gaaacattat taaactgtac taacaataca gaaacatatt ctctttgtcg     7860

ctttttatca ccaaaactga atggcaaata tgtcttgaca ttacttggat gaactgtggc     7920

tagcaaaatg gaattaactt agccactata attttttaaa acattaaagt ttctaaattg     7980

tttttggggc cgagtaacgc agagtcaata aaggtggtta tattgtaagc ttttagatgg     8040

tgcttaagaa ttcttatctt tttaaatagc agtatttttt ttttaagaat aaattgtaag     8100

gagcaaataa ggcagaatgc cactctaccc tcaggtcaat tttatggtat atgaaaatgc     8160

cagtaatatt tgtgccactt gccaactcgg gggaggaggg gcttttccct tactggatac     8220

ttttgttata gtttgactat gtcattatgt tgtttagaga gcctccacaa tgagaagttg     8280

ccactgcagg gctaactcgc cttcagaaat aatcagaatg attcaagggt caaaccactt     8340

tcatccctta aaatataggg actaatattt ctttttcttt tttttaaaaa aaacatttct     8400

tctgtggctt agaaatgtgc cagtgtgttc aaaacattta caccaatttc accagattta     8460

ggacctatta aaaattcaaa caagtttctt tttttttttt ttttttctgt gtaacaggga     8520

tttttaaata acggactata tgcattcttt tgttatttca cacttcagtt aaagtgataa     8580

caatggtaaa ctgtgatcat tatcagactg actgaatgct ttctgatttc cagtgagtga     8640

tctagttcta cgtattacac aggtgtaata tctgtgagtg taaataactg gaactgtaca     8700

ctgattaaca tgacagtttc tcttttgttg ttcttatctg tactgtatta tagtatgtgg     8760

gtataaatat ctacaagtat acacacatat gtacttgtat tccactattg taacctgaaa     8820

gaaagactat gtattccctt ttttaattcc gtactggtat ttgtgttatt taaaaagcaa     8880

aattctgctc tatttagttg tataatatta gaggatactt tgctgtgcac aattccaagt     8940

gccttagaac attgtttagc tttcctaagt atatataaat gcatatatgt ataaaattgg     9000

gaaaagttac ctcaataaaa tcattgggaa atccccagtt ttagtttgtt ccagtttctc     9060

ttatatttgg atagtgctca gcctttttaa atgaaaaaag aaaaaagagt aagacaactt     9120

ccctaattgc ctgttatttc agcttcacct aagtttttaa cacctctttg tatgtaaggt     9180

cttgagacat gtaaggcctg gtacttttta tttaaaatgt ctgtctaaag aattactgct     9240

cttaaaagaa acttccagta ttttttttaa cttgctatct ttttatgtct gaggtatttg     9300

atattgatgt ttttattgcc attattatat gtaaacataa aagatagtcc atttagagtt     9360

tataatatag aaaataaaca gacttcctca ttaaaaaaaa aa                        9402


<210>  497
<211>  9300
<212>  DNA
<213>  homo sapiens

<400>  497
agtgcatgaa gtatgctcag tgtgccagca agggctgata atcagcagaa ggacagggtg       60

cttcgttagt cagaagagcc agggcttccc ggctgccagg ctacagaact cgcctcgcca      120

ctcctgagac atggacaacg ccgttgacgg actggacaaa gcttctatag caaactcaga      180

tggccccaca gcaggttccc aaacacctcc cttcaaaaga aaggggaaac tatccaccat      240

tggtaaaatc tttaagcctt ggaaatggag gaaaaagaag accagcgaca aatttagaga      300

aacctcggca gtattagaaa ggaagatatc cacacgacaa agtagagagg agctgataag      360

aaggggagtg cttaaggaat tgcctgatca agatggagat gtaacagtta actttgaaaa      420

ttcaaacggg cacatgatac ccatcggaga ggaatctacc cgagaggaaa atgtagtaaa      480

gtctgaagaa ggtaatggct ctgtatctga aaaaacacca cctctggagg aacaggcaga      540

agataagaaa gctggctcct ctcattcaaa aaaaacaact ggctctaaag catcagcttc      600

gccatccact tcatccacct catctcgtcc caaagcttca aaggagacag tttctagcaa      660

agcagggaca gtggggacca ccaagggcaa gagaaaaact gacaagcagc caataacttc      720

tcacctgtcc tcagacacaa caacttctgg cacatccgac ctgaaaggag agcctgcaga      780

gaccagagtg gagagtttca aactcgaaca gactgtccct ggagctgagg agcagaacac      840

aggcaaattc aagtccatgg tccctccacc ccctgtggct ccagcacctt ctcctctggc      900

cccccctctc cctcttgagg atcagtgcat tactgcctca gacactccag ttgtcctcgt      960

cagcgttgga gctgacctgc ccgtctctgc cttagaccca agtcagcttc tttgggctga     1020

agagccgacg aacagaacca ctctctactc aggcactggc ttaagtgtta acagagaaaa     1080

tgcaaaatgt ttcacaacca aagaggagct ggggaagaca gtgcctcagc tactgactcc     1140

tgggctgatg ggcgaatctt cagaatcctt tagtgcctca gaagatgaag gccacaggga     1200

ataccaagcc aatgactctg actcggacgg gcctatcttg tacaccgatg atgaggacga     1260

agacgaagat gaggatggca gtggagaaag tgctttggca agtaaaatac gccggaggga     1320

tactcttgct atcaaacttg gcaacagacc atctaagaaa gaactagagg acaaaaacat     1380

cttgcagcgt acatctgaag aagagaggca ggaaatccga caacaaattg gaaccaagtt     1440

agtcaggagg ctgagccaga ggcccacaac tgaagaatta gagcaaagaa acatcctaaa     1500

acaaaagaat gaagaagagg aacaagaagc aaaaatggaa cttaaacgca gactcagcag     1560

aaagctcagc ctgagaccca cagtggcaga gctacaagct cgaaggatcc tgcgatttaa     1620

cgagtatgta gaagtcacgg attctcctga ctatgaccgc cgagcagaca agccctgggc     1680

caggttaaca cctgcagaca aggcagcaat aaggaaagaa ctaaatgaat ttaaaagcac     1740

agaaatggaa gttcatgaag agagtcgaca gtttacaagg tttcatcgtc cataacgaag     1800

agtgagacta tttggaaaca gagactgatc atctttgggg gaagccctgc ttcctgaaaa     1860

cctgatattg cactgggatt tgaatgtgtg tgtttccgtt taacttgtgg tgaaggaagt     1920

gtgtgactca gcttggctgg gaagtgctcc tcacctgtgt ggcccagatg gctccaacaa     1980

gcaaaaggaa ggatgcagtg actcttgctg cccagaatgc acagcgatgg taagagacac     2040

cgtggatatt cttcatcaga agctttaatc aaagaagatg agcagaagac aatcactggc     2100

tccctgttac cagaaagcca aattttataa tgcgggtgaa agaaaaatat agattaaaat     2160

tgctgggcac tgaaaagggg tgggagttgg aaatcagaaa gaaagagaaa tatttcatta     2220

tgttaatgaa gaaaagagaa aattgaagca taaatgtatt tttgaagtag ttattcggta     2280

gctgagaact tattaaggga tttaggaatt taacctcctg atgtggattc ctcaaagact     2340

tgatcggaga atactcttgt ttcaccatta tgttggtaca gtatagtacc attattttat     2400

gttgtgccag tgaatccagt tgccagaaat aagtctgaat gttttcatgc atctttttct     2460

taaatgcaag agcttctact gactcttaac aagcatgctt acccaaattt tgttgcatgc     2520

ttttaagtag cattagctat gcacacttga catttttaaa tatccctttc ctagtgtacc     2580

agccttcaca ggataagagg actgggaata aagtcagatg taatgtgacc ctagaaaact     2640

gtagcaagct tcagaaataa atcttttgat ctttccctat cttgattaga tccaaagtca     2700

aagcaaccat acttcaccta gagaagacag tattggcaat catgacacct gtaataaaaa     2760

cttgaatcca aagtcaaaac ttaagcaaga tacaaatgtg ctgcctgcag ttagtcctgc     2820

atgggaataa ggactagtta tttttttagt gctgcatttt tttaaagttg gattgctgct     2880

atttaaaaaa aaaaaaagga cacagatcaa aaaaacaccc aaaggcttaa cagaacatgg     2940

aaagttccca ctaagttgtg tgtgaggaaa tcctcatctt gtattttaag aatctgcaga     3000

tggcatccat agatacagta cagtatttac tgtcaatgca aaagaatcag tgaggttaaa     3060

gtagtggaag ttttccctat gagcctacag tctgtattgt ttacattaag aaactctcta     3120

ttattgtgtt gctattttcc atggagtcac aggcacacta tgacttctgc tcccaaatac     3180

atatgaccat atgtaaatac caccttgcat ttcattgttc ttcacaagtg ctttgtgccc     3240

ctttaattaa aaacacatga aatgaataac aaaacaagac ccaaatagag tttattttat     3300

tctcagagtt tggactacaa ttttctaaga tgtttctggt tcaagactgt cattttctat     3360

ttcaaccgaa aagtaagcat ttaacccggt gaataaatgt agatcctgcc attcattggt     3420

attttaaaga accacttgaa atcggatcat tttatttaaa aataaaaaat gttaatgcca     3480

gttggcctac tataaaaagc caggaccatg ttagaattag gaaaagtaac cagcattact     3540

gcacctcttg ttagactctg tgcattaata aaacacacct agagtctgtt gtcatttcac     3600

taataggata agacaaattt tttgctttga aaaaattttt ctgcatgccc aggtgtctgt     3660

ctctggctga ggttttgtct attttacagt gtttcaatcc agccataaaa attaacttgt     3720

gatttttttt ttcccaaagt catgcttttc cttaattata tttttatttt attattttag     3780

tgtcttgaga aaaataccaa gagatataat gtttctttta attgtctatg cttaatcatc     3840

tttaaacact ttttaaattt ctaaccacaa gacctctcta taatggtaaa tgtaagacat     3900

caccatttta tcactcaaag tatgttattg aaagtttcta tttggttgat aaaaggaaca     3960

attttttccc acttttgatg cctgtgatgc aattttttat tgcctacaat gagatacact     4020

tagtacaaaa aatgaaaatc tggtatttca aaattgcatt tcttgtataa taggtcagat     4080

ttattaacta ctcatacttt ttctttacac taatcgatac atttagaaaa aattttctaa     4140

gttagagaca agtttaaaag taaaaaaaaa aaaaaattag ccactgctag tctactgttt     4200

aggtaatcgg aatcaccaat tattttatta gaatgatggc ttgagtaaaa agctgtggaa     4260

agaattaaag gattatgagc taagctgtat tttgcagaat atggttctat tttagtagag     4320

cagagatgag acatatcccc accggccacc cagccagagg tctcctacct gggggcccta     4380

aagggatgca gaggtctggc ccaccctccg tgcataggca cctctgtcca ccaccagcgt     4440

ttcagcaatc caaccagtaa gcatatgctg tataggaaaa ataaaagtgt gtgggaattg     4500

gatttctttt gttgtaacac aattccaggt ttttggctat ttaaagtttg acattaggct     4560

gacatcgagg aagtaagtgg gttttcctga gttcccaaga tatgattaag gaagaaaaca     4620

aacccatctc caggaagatc ccaggcagga aagaactaga cagatgtaga aaccaaagtg     4680

accattttag tttttttatt ggagaataaa acattaatat tagggtatta agaagatgct     4740

cagcaagctt gatcagaatc ttcatggtca ttaccaatca gtctgacaaa atagttctct     4800

ggtagtcagc attcatttaa ggcagcttgc ctgataattt cctgtgttat gtgaagtgtc     4860

ttgcactttc acatgttagc tataattcct taaattactt aactgaaatc tgtaatagag     4920

aaccattttg gcatttgaac agctatttta catggagaaa aagcaaacac atctgtttgc     4980

tttacccaga aaaactgact ttctggtttc atcttcatat tgtttagtag cataatgaga     5040

gtagtccttt atctttctct aatgttagta aatatattct gttagtagga agttctgaaa     5100

ttgaagggaa aatatattta aggaaataaa ggaattcaat acacccttca aaagtcacca     5160

aatactgaaa ataagagatg agtccttaaa acctgagtca aaaaaggtcc agttttacag     5220

cctgcaatta attcagggct gcgttggcat taaaaaagaa aatatatata tatatatata     5280

tatatatata tatatatata tatatgtata ttatatatac agtagcttac acttaaaaga     5340

ggaaaaattt gcattaacat tgcatattct gatatgtacc atattaacac ataacaggca     5400

ttttatttat gcttcataga atcagacaga cacaactttc aaaaatctta ctgtattcac     5460

aatagaaaag ggtagtcttg tctaccacag aggagtatgt ccacacttaa taatgaaaac     5520

tttcttcctt tcctgcccaa aaatttcttc agtctgttat tatttttaag tgccccttgc     5580

tgcaaatttc aaacagagca agaaatcttc ctcagagtag gtggtatgaa attaaactag     5640

tacaatatat atgaattcat gtcatttacc cctgagtatg gtagaattgt taaagcattc     5700

ttaaattcca attatatgaa gcctatcatt actaggaaaa gtatattctt tgggataaga     5760

attaatttct tcacactatt agagcatgtt gtgagtagta aggaactact tagatgcaat     5820

ttatttacag aattgtccct tgacctcttg aaatggctag atctttcact actgtgtagg     5880

tagtctctac ttactggtag gatagattac attgctttac tggacaaagc agaatgaact     5940

tatataacta aaatatgtcc tatattggct gggtgcggtg gcttacacct gtaataccag     6000

cactttggga ggccaaggtg ggtggatcag ttgaggtcag gagttcgaga ccagcctggc     6060

caacatggtg aaaccctgtc tctactgaaa atacaaaaaa aaaaaagtat ctgggcatgg     6120

tggcttgtgc ctgtaatccc agctacttgg gaggctgagg cagggaaatc gcttaaaccc     6180

gggaggtgga ggttgcagtg ggcccagatc gtgccactcc actccagcct gggagacaga     6240

gcaagactcc atctcaaaat aataataata gtaataatga ataaaataaa ataaaatatg     6300

tcctccaggg aaaagcaatg acagagtaat caccaaatta ataggaacat ctttctagag     6360

aaagtacatg cccagttagt tcaaacccag gtttcaaaga agtagcactg ggctctactg     6420

taaaggcagg cagtgaccaa gaggtggtgg ggagagaggt agagtaccct caaatcattc     6480

ccattttcac ttccaatttc ccttttgtaa tcattaagct taagctatgt atggaaatgc     6540

aaagcaccat tagcatttct agaaagcagc tggaacctta cccaccaatg cttttttgaa     6600

gacagtatca tcccaaattt aaaaatccta ttgtatatgt tgtaaaattt ctggcaaaga     6660

aatggaggat cctgtggcag ctattcccac ctaaagccaa ccctataagg atgggtcatt     6720

ttttagccat gctaggattt actgcacaca caaaaaatgt catttagctt gtcacattgc     6780

tagcacagct gcacatatga gcaaagcact gttggtctgt gtttctcagt gggggtactc     6840

ttggcatttg gagctggata ggtctttgct gtacagaatc atcccatgca ttgccagatg     6900

tttaatatcc caggcccctg ctgactaaat gtcagtagca ttctcagtca ttgtaaacac     6960

caagaataaa aagcattccc ccaggttcaa atgccctccc tgggaggttg gtatcacctc     7020

ccctgaatgc cactgtctac tgcattttga ggacacaggg agaaaaagtg cctatcctca     7080

aacattgtct ctgctgcctt gcatttcttt gggccctgaa tggtttttct cccttcattt     7140

ttcgagcctt tctctcagtg cagctgttct tcagggagga ggttactggg cagccttggc     7200

cattcagtgg gcatggggac ttggcctagt ccctatatat atatacttaa agtccctata     7260

tatacttaaa ggagagatca tacatgaaga aagctttttt tttttttttt ttttttgcct     7320

tacaactttt ctttagaacc acattattgg tcataatcct tgttactgtc atgaggattg     7380

ttgcatgggt taaacacaaa cacagactag caatgcactt gaacaaacct ggtggtcttt     7440

ggaaataaat caccattaga tttcacctgg ttatgctgca tcccataagt tccaaatgaa     7500

tcacctgctt atcctattaa cgaagcattt aattcacaca caaatgcttg aatttcccct     7560

gtataaatgt agtcatgcga ttcaactttt ctaataagat ttgtgaatgc tgcatcatga     7620

tgaaaatgtg gattaactgt gggttgcatg cctgttgttc atacttcagt gatggtcaca     7680

cacaaaacaa gatgagtttt acttaggtga aacattatta aactgtacta acaatacaga     7740

aacatattct ctttgtcgct ttttatcacc aaaactgaat ggcaaatatg tcttgacatt     7800

acttggatga actgtggcta gcaaaatgga attaacttag ccactataat tttttaaaac     7860

attaaagttt ctaaattgtt tttggggccg agtaacgcag agtcaataaa ggtggttata     7920

ttgtaagctt ttagatggtg cttaagaatt cttatctttt taaatagcag tatttttttt     7980

ttaagaataa attgtaagga gcaaataagg cagaatgcca ctctaccctc aggtcaattt     8040

tatggtatat gaaaatgcca gtaatatttg tgccacttgc caactcgggg gaggaggggc     8100

ttttccctta ctggatactt ttgttatagt ttgactatgt cattatgttg tttagagagc     8160

ctccacaatg agaagttgcc actgcagggc taactcgcct tcagaaataa tcagaatgat     8220

tcaagggtca aaccactttc atcccttaaa atatagggac taatatttct ttttcttttt     8280

tttaaaaaaa acatttcttc tgtggcttag aaatgtgcca gtgtgttcaa aacatttaca     8340

ccaatttcac cagatttagg acctattaaa aattcaaaca agtttctttt tttttttttt     8400

ttttctgtgt aacagggatt tttaaataac ggactatatg cattcttttg ttatttcaca     8460

cttcagttaa agtgataaca atggtaaact gtgatcatta tcagactgac tgaatgcttt     8520

ctgatttcca gtgagtgatc tagttctacg tattacacag gtgtaatatc tgtgagtgta     8580

aataactgga actgtacact gattaacatg acagtttctc ttttgttgtt cttatctgta     8640

ctgtattata gtatgtgggt ataaatatct acaagtatac acacatatgt acttgtattc     8700

cactattgta acctgaaaga aagactatgt attccctttt ttaattccgt actggtattt     8760

gtgttattta aaaagcaaaa ttctgctcta tttagttgta taatattaga ggatactttg     8820

ctgtgcacaa ttccaagtgc cttagaacat tgtttagctt tcctaagtat atataaatgc     8880

atatatgtat aaaattggga aaagttacct caataaaatc attgggaaat ccccagtttt     8940

agtttgttcc agtttctctt atatttggat agtgctcagc ctttttaaat gaaaaaagaa     9000

aaaagagtaa gacaacttcc ctaattgcct gttatttcag cttcacctaa gtttttaaca     9060

cctctttgta tgtaaggtct tgagacatgt aaggcctggt actttttatt taaaatgtct     9120

gtctaaagaa ttactgctct taaaagaaac ttccagtatt ttttttaact tgctatcttt     9180

ttatgtctga ggtatttgat attgatgttt ttattgccat tattatatgt aaacataaaa     9240

gatagtccat ttagagttta taatatagaa aataaacaga cttcctcatt aaaaaaaaaa     9300


<210>  498
<211>  2645
<212>  DNA
<213>  homo sapiens

<400>  498
ataggagtcc cgaaggccga gagtgagtga gtgagtggga gcggggcggc tgcggctcct       60

cctgtccggg gcggagccct gcgtcgcggg cctggggagg ccccgccagc acccttgacg      120

tctgggtccc gagcagtgcg gcagccacac gacactgagg cgagcgagtg ggtgtgtgcg      180

tggggggtca gccaaacttc ctgtcccgcg ctcgagctgc ttccggcggg agccggaaga      240

cgctgtgtgt ggacggaatt cgggaccgac tgacggccgg ccggcttccc ggaactggaa      300

ggttacattg attacccacc tagtacaaca tcttacggga agagcatagt atttcctaga      360

ggaatatgaa cataacagga aggtatcatt ggctctgaat taaatttgaa cttgtcccct      420

gaatagctac aggttttgga agctgaatca atgttatcag atgagttaga atccaaacca      480

gagctcctgg tacagtttgt tcagaatacg tccatcccat tgggacaggg gcttgtagaa      540

tcagaagcta aagatattac ttgcttgtcc ctccttcccg tgactgaagc ctcagaatgc      600

agtcggctaa tgttaccaga tgatactaca aatcattcta actcctccaa ggaggtccct      660

tcctcagctg ttttgagaag ccttcgggtg aatgtgggtc cagacggaga ggagacgaga      720

gctcagactg tacagaaatc cccggagttt ttgtccactt cagagtcttc tagcttgttg      780

caagatctac agccaagtga tagcacttct tttattcttc ttaacctaac aagagcaggt      840

ctgggctctt cagctgagca cttagtgttt gtacaggatg aggcagaaga ttcagggaat      900

gatttcctct ccagtgagag cacagacagt agcattccat ggttcctccg ggttcaggag      960

ttggcccatg acagtttgat tgctgctact cgtgcacaac tggcaaagaa tgcaaaaacc     1020

agcagcaatg gagaaaatgt ccaccttggt tctggtgatg ggcagtcaaa agattctggg     1080

ccccttcctc aagtggaaaa gaagctcaag tgtacagttg aaggttgtga ccggacattt     1140

gtatggccag ctcactttaa ataccacctc aagactcatc gaaatgaccg ctccttcatc     1200

tgtcctgcag aaggttgtgg gaaaagcttc tatgtgctgc agaggctgaa ggtgcacatg     1260

aggacccaca atggagagaa gccctttatg tgccatgagt ctggctgtgg taagcagttt     1320

actacagctg gaaacctgaa gaaccaccgg cgcatccaca caggagagaa acctttcctt     1380

tgtgaagccc aaggatgtgg ccgttccttt gctgagtatt ctagcctccg aaaacatctg     1440

gtggttcact caggagagaa gcctcatcag tgccaagtct gtgggaagac cttctctcag     1500

agtggaagca ggaatgtgca tatgagaaag catcacctgc agctgggagc agctgggagt     1560

caagagcagg agcaaactgc tgagccacta atgggcagta gtttgcttga agaggcttca     1620

gtacccagta aaaacctggt gtctatgaat tcccagccca gccttggtgg agagtccttg     1680

aacctaccaa ataccaattc tatcctggga gttgatgatg aggtgcttgc tgaaggatcc     1740

ccacgttccc tgtcttcagt gcctgatgtg acacatcacc tggtgaccat gcagtcaggg     1800

aggcaatcat atgaagtttc tgtcttaact gcagtaaatc cacaagagtt actaaaccaa     1860

ggagatttaa ctgaaagacg gacatgagcg tgggtgctga ctcctggaag agcaactcta     1920

tctgatctca aaatgcgtat actgggaaca ggatgcctta gcccacaaca gaaccagaat     1980

gaatctttga aggcacaaga ctctgctttt gccactcttc ctctttcctg gtatagaaga     2040

tggatgtagg agagcttctt ttctaactac catctgatca gacaaggaat gaagcaatga     2100

ctgtgggctg ggaaactgta cctacctctc ttcccactgc aaatttctgg gatagaccaa     2160

aagtgaattt gattatgtgt tggctgaagt tcttcattct gactgttgag gggaggtttt     2220

cctttgaaga gttttcatcc cagactcagc tgtcttttca catggatgaa ataattcctg     2280

ctaccaacaa cagagcttca ccaggaagtt gagttttcaa gatgccttgt tgctttgaag     2340

aagggagtga tgtcaattct cttgttacat tctcccttta gcaacctgag taagagactc     2400

tctgccactg ggctgcaaaa aaataaatta cttgaatctc cccttggccc aggctgaggt     2460

actatcttgt cctatacact tctacttggt cactttgctt tcttcgttaa tggaacatac     2520

agtagcatgt taagagggat ttcatgtttt tgttttttta aagttaaaaa ttacatgatg     2580

cagagattca ggttttcctt taaataaaca aaacagccca gtcagttctt tggcaaaaaa     2640

aaaaa                                                                 2645


<210>  499
<211>  2645
<212>  DNA
<213>  homo sapiens

<400>  499
ataggagtcc cgaaggccga gagtgagtga gtgagtggga gcggggcggc tgcggctcct       60

cctgtccggg gcggagccct gcgtcgcggg cctggggagg ccccgccagc acccttgacg      120

tctgggtccc gagcagtgcg gcagccacac gacactgagg cgagcgagtg ggtgtgtgcg      180

tggggggtca gccaaacttc ctgtcccgcg ctcgagctgc ttccggcggg agccggaaga      240

cgctgtgtgt ggacggaatt cgggaccgac tgacggccgg ccggcttccc ggaactggaa      300

ggttacattg attacccacc tagtacaaca tcttacggga agagcatagt atttcctaga      360

ggaatatgaa cataacagga aggtatcatt ggctctgaat taaatttgaa cttgtcccct      420

gaatagctac aggttttgga agctgaatca atgttatcag atgagttaga atccaaacca      480

gagctcctgg tacagtttgt tcagaatacg tccatcccat tgggacaggg gcttgtagaa      540

tcagaagcta aagatattac ttgcttgtcc ctccttcccg tgactgaagc ctcagaatgc      600

agtcggctaa tgttaccaga tgatactaca aatcattcta actcctccaa ggaggtccct      660

tcctcagctg ttttgagaag ccttcgggtg aatgtgggtc cagacggaga ggagacgaga      720

gctcagactg tacagaaatc cccggagttt ttgtccactt cagagtcttc tagcttgttg      780

caagatctac agccaagtga tagcacttct tttattcttc ttaacctaac aagagcaggt      840

ctgggctctt cagctgagca cttagtgttt gtacaggatg aggcagaaga ttcagggaat      900

gatttcctct ccagtgagag cacagacagt agcattccat ggttcctccg ggttcaggag      960

ttggcccatg acagtttgat tgctgctact cgtgcacaac tggcaaagaa tgcaaaaacc     1020

agcagcaatg gagaaaatgt ccaccttggt tctggtgatg ggcagtcaaa agattctggg     1080

ccccttcctc aagtggaaaa gaagctcaag tgtacagttg aaggttgtga ccggacattt     1140

gtatggccag ctcactttaa ataccacctc aagactcatc gaaatgaccg ctccttcatc     1200

tgtcctgcag aaggttgtgg gaaaagcttc tatgtgctgc agaggctgaa ggtgcacatg     1260

aggacccaca atggagagaa gccctttatg tgccatgagt ctggctgtgg taagcagttt     1320

actacagctg gaaacctgaa gaaccaccgg cgcatccaca caggagagaa acctttcctt     1380

tgtgaagccc aaggatgtgg ccgttccttt gctgagtatt ctagcctccg aaaacatctg     1440

gtggttcact caggagagaa gcctcatcag tgccaagtct gtgggaagac cttctctcag     1500

agtggaagca ggaatgtgca tatgagaaag catcacctgc agctgggagc agctgggagt     1560

caagagcagg agcaaactgc tgagccacta atgggcagta gtttgcttga agaggcttca     1620

gtacccagta aaaacctggt gtctatgaat tcccagccca gccttggtgg agagtccttg     1680

aacctaccaa ataccaattc tatcctggga gttgatgatg aggtgcttgc tgaaggatcc     1740

ccacgttccc tgtcttcagt gcctgatgtg acacatcacc tggtgaccat gcagtcaggg     1800

aggcaatcat atgaagtttc tgtcttaact gcagtaaatc cacaagagtt actaaaccaa     1860

ggagatttaa ctgaaagacg gacatgagcg tgggtgctga ctcctggaag agcaactcta     1920

tctgatctca aaatgcgtat actgggaaca ggatgcctta gcccacaaca gaaccagaat     1980

gaatctttga aggcacaaga ctctgctttt gccactcttc ctctttcctg gtatagaaga     2040

tggatgtagg agagcttctt ttctaactac catctgatca gacaaggaat gaagcaatga     2100

ctgtgggctg ggaaactgta cctacctctc ttcccactgc aaatttctgg gatagaccaa     2160

aagtgaattt gattatgtgt tggctgaagt tcttcattct gactgttgag gggaggtttt     2220

cctttgaaga gttttcatcc cagactcagc tgtcttttca catggatgaa ataattcctg     2280

ctaccaacaa cagagcttca ccaggaagtt gagttttcaa gatgccttgt tgctttgaag     2340

aagggagtga tgtcaattct cttgttacat tctcccttta gcaacctgag taagagactc     2400

tctgccactg ggctgcaaaa aaataaatta cttgaatctc cccttggccc aggctgaggt     2460

actatcttgt cctatacact tctacttggt cactttgctt tcttcgttaa tggaacatac     2520

agtagcatgt taagagggat ttcatgtttt tgttttttta aagttaaaaa ttacatgatg     2580

cagagattca ggttttcctt taaataaaca aaacagccca gtcagttctt tggcaaaaaa     2640

aaaaa                                                                 2645


<210>  500
<211>  4596
<212>  DNA
<213>  homo sapiens

<400>  500
gaaaacttcc tggagaagga tggattttac cctgtaaaag aagaaagaca tggatgcata       60

agaagagggt tgaagagggg gaggcctcag acttctcgct ggcctgggat tcctccgtga      120

cagcagcagg aggcctagaa ggagagccag agtgcgatca gaaaaccagc cgtgcgctgg      180

aagacaggaa cagcgtgaca agtcaagagg agagaaatga ggatgatgaa gacatggagg      240

atgaatcaat ttacacctgc gatcactgtc agcaggactt cgagtctctg gcagacctga      300

cggaccaccg ggcccaccgc tgtcctggag atggtgatga cgacccacaa ctctcctggg      360

tggcctcgtc tccctccagc aaggatgttg cgtcacccac gcagatgatc ggagatggtt      420

gtgacctcgg cctcggcgag gaggaagggg gcacgggcct gccataccct tgccagttct      480

gcgacaagtc cttcatccgc ttgagctact tgaagaggca cgagcagatc cacagcgaca      540

agctgccgtt caagtgcacc tactgcagcc gcctcttcaa gcacaagagg agccgtgacc      600

ggcacatcaa gctgcatacg ggcgacaaga agtatcactg ccacgagtgc gaggcagcct      660

tctcccgcag cgaccacctc aagatccacc tgaagaccca cagctccagc aagcccttca      720

agtgcactgt gtgcaagcgc ggcttctcct ccaccagctc gctgcagagc cacatgcagg      780

cccacaaaaa gaacaaggag catctggcca agtcggagaa ggaagccaag aaggacgact      840

tcatgtgcga ctactgcgag gacaccttca gccagacgga ggagctggag aagcacgtgc      900

tcacccgcca cccgcagctg tccgagaagg cggacctgca gtgcattcac tgccctgagg      960

tcttcgtcga cgagaacaca ctgctcgccc atatccacca agcccacgcc aaccagaaac     1020

acaagtgccc catgtgccct gagcagttct cctcagtgga aggtgtctac tgccacctgg     1080

acagccaccg gcagcccgac tccagcaacc acagtgtcag tcccgaccct gtactgggca     1140

gcgtggcctc catgagcagc gccacacccg actccagcgc ctctgtggag cgtggctcca     1200

ccccggactc caccttgaag ccgctgcggg ggcagaagaa gatgcgggat gacgggcagg     1260

gctggaccaa ggtggtctat agctgcccct attgttccaa gcgggacttt aacagcctgg     1320

ccgtgctgga gatccacctg aagaccatcc acgcggacaa gccccagcag agccacacat     1380

gtcagatctg cctggactcc atgcccaccc tctacaacct caacgagcac gttcgcaagc     1440

tgcacaagaa ccatgcctac cctgtgatgc agtttggcaa catctctgcc ttccactgca     1500

actactgccc cgagatgttc gccgacatca atagcctgca ggagcacatc cgcgtctccc     1560

actgcggccc caacgccaac ccctctgacg gtaataatgc tttcttctgc aaccagtgct     1620

ccatgggttt ccttactgag tcctccctca ccgagcacat ccagcaggcc cactgcagtg     1680

tgggcagtgc caaactagag tctccggtgg tgcagcccac gcagtccttc atggaggtct     1740

attcctgccc ctactgcacc aactccccca tctttggctc catcctgaaa ctcaccaagc     1800

acatcaagga gaaccacaag aacattccac tggcccacag caagaagtcc aaggccgagc     1860

agagcccagt ctcgtccgat gtggaggtgt cttccccgaa gcggcagcgg ctctcagcaa     1920

gcgccaactc catctccaat ggggagtatc cttgcaatca atgcgacctc aagttctcca     1980

actttgagag cttccagacc cacctgaagc tgcacctgga gctgctgctg cggaagcaag     2040

cgtgccccca gtgcaaagag gactttgact cccaggagtc cctcctgcag cacctgacag     2100

tgcattacat gaccacgtcg acccactatg tgtgcgagag ctgcgacaag caattttcct     2160

cggtggatga cctgcagaag cacctgctgg acatgcacac ctttgtgttg taccactgca     2220

ccctgtgtca ggaggtcttc gactccaagg tgtccatcca ggtgcacctg gcggtgaagc     2280

acagcaatga gaagaagatg taccgctgca cggcctgcaa ctgggacttc cgcaaggagg     2340

ctgacctgca ggtgcacgtc aaacacagcc acctgggcaa cccggccaag gctcacaagt     2400

gcatcttctg tggggagacc ttcagcaccg aggtggagct gcagtgccac atcaccacac     2460

acagcaagaa gtataactgt aagttctgca gcaaggcctt ccacgccatc atcctgctgg     2520

agaagcacct gcgggagaag cactgtgtgt ttgatgctgc gaccgagaac ggcacggcca     2580

atggggtacc cccaatggcc accaagaaag ctgagcctgc tgacctgcag ggcatgctgc     2640

ttaagaaccc tgaggcacct aacagccatg aggccagcga ggatgacgtg gacgcgtcgg     2700

agcccatgta cggctgtgac atctgtgggg cggcctacac catggaggtg ctgctgcaga     2760

atcaccggct gcgggaccac aatatccggc cgggcgagga tgatggctca cgcaagaagg     2820

ctgagtttat caagggcagt cacaagtgca acgtttgttc acggactttc ttctcggaga     2880

acgggctacg ggagcacctg cagacgcacc ggggccctgc caagcactac atgtgtccca     2940

tctgtggtga gcgcttccct tcgctgctga cgctcaccga acacaaggtg acccacagca     3000

agagcctgga cacgggcacc tgtcgcatct gcaagatgcc cctgcagagc gaggaggagt     3060

ttattgagca ctgccagatg caccctgacc tgcgcaactc actcacgggc ttccgctgtg     3120

tggtctgcat gcagacagtc acttccacgc ttgagctcaa gatccatggc accttccaca     3180

tgcagaagct ggcgggcagc tcagcggcgt cctcccccaa tggccagggg ctgcagaagc     3240

tctacaagtg cgccctgtgc ctcaaggagt tccgcagcaa gcaggacctg gtgaagcttg     3300

acgtcaatgg gctgccctac ggcctctgcg ccggctgcat ggcccgcagc gccaacggac     3360

aggtgggtgg cctggccccg cccgagcccg ccgaccggcc ctgtgccggc ctccgttgcc     3420

ccgagtgcag tgtcaagttt gagagtgccg aagacctgga gagccacatg caggtggacc     3480

accgtgacct cacgccggag accagtgggc cccggaaagg cacccagaca tcgccagtgc     3540

cccggaaaaa gacataccag tgcatcaagt gccagatgac cttcgagaac gagagagaga     3600

tccaaatcca cgttgccaac cacatgattg aggaaggcat caaccacgag tgtaagctgt     3660

gcaaccagat gttcgactcc ccggccaagc tcctctgtca cctcattgag cacagcttcg     3720

agggcatggg cggcaccttc aaatgccccg tgtgtttcac agtcttcgtc caggccaaca     3780

agttgcagca gcacatcttt gccgtgcacg ggcaggagga caagatctac gactgctcac     3840

agtgccctca gaagttcttc ttccagaccg agctgcagaa ccacacgatg agccagcacg     3900

cacagtgagg gatcgctcaa caggacacct ctccgcagaa ggcttgccgg agacgccgtg     3960

gggagggcca tttgaacatt acatccaatc aaagtgtcat ttgcaaccca gatgtaaaac     4020

tctaatgatt tggccatgag gcgctgctat tataagcagc tggaaatgaa tattaatggc     4080

agagattaaa agtattccat gctcagtatt ttttattgtc ctgctacagc tagtgtgctt     4140

ttagactttc cgccgcagac tacatttcta gagttagaga aacctgcttt ttaaggctat     4200

tgtcctttgt tccttcatgt attatattga tagtttttaa aaaagaatta gtgtgatttt     4260

ttttctttgc ttcttttttt tctttcttgt ttttcttccc ccccaccccc cacccccttc     4320

ggttaactac tttttaattg caattctagg taattgtgca tcgtgatgtg attgcttggc     4380

tattgtctga atatttcctt ttaatttttt aattaaagac taatgctttg attggatttg     4440

ccagttcacc ggacagtgat taaaactatg taatgaatat aatcggtttc agtgcaactg     4500

gatggtctgc ttttaaatgt gacttaatct gactgcagta actagtacag ttcaataaag     4560

ggaatccatg cgattagcaa aaaaaaaaaa aaaaaa                               4596


<210>  501
<211>  2142
<212>  DNA
<213>  homo sapiens

<400>  501
cggccccccg cattccccgc ccccacctcc ccgccttgtt gtccaacttc tcccggagca       60

gccggagagc aggcgtcggg acgcagcaaa gagaggagag accccagagt cagaaggagt      120

gagaaccctg acccctaatc ccactgcatc cagccaatag gagcccagcc accatggcgg      180

agctgcagga ggtgcagatc acagaggaga agccactgtt gccaggacag acgcctgagg      240

cggccaagga ggctgagtta gctgcccgaa tcctcctgga ccagggacag actcactctg      300

tggagacacc atacggctct gtcactttca ctgtctatgg cacccccaaa cccaaacgcc      360

cagcgatcct tacctaccac gatgtgggac tcaactataa atcttgcttc cagccactgt      420

ttcagttcga ggacatgcag gaaatcattc agaactttgt gcgggttcat gtggatgccc      480

ctggaatgga agagggagcc cctgtgttcc ctttgggata tcagtaccca tctctggacc      540

agcttgcaga catgatccct tgcgtcctgc agtacctaaa tttctctaca ataattggag      600

ttggtgttgg agctggagcc tacatcctgg cgagatatgc tcttaaccac ccggacactg      660

ttgaaggtct tgtcctcatc aacattgatc ccaatgccaa gggttggatg gattgggcag      720

cccacaagct aacaggcctc acctcttcca ttccggagat gatccttgga catcttttca      780

gccaggaaga gctctctgga aattctgagt tgatacaaaa gtacagaaat atcattacac      840

atgcacccaa cctggataac attgaattgt actggaacag ctacaacaac cgccgagacc      900

tgaactttga gcgtggaggt gatatcaccc tcaggtgtcc tgtgatgctg gtggtaggag      960

accaagcacc tcatgaagat gcagtggtgg aatgtaactc aaaactggac cccacccaga     1020

cctcgttcct caagatggct gactccggag gtcagcccca gctgactcag ccaggcaagc     1080

tgaccgaggc cttcaagtac ttcctgcaag gcatgggcta catggcctca tcctgcatga     1140

ctcgcctgtc ccggtctcgt acagcctctc tgaccagtgc agcatccgtt gatggcaacc     1200

ggtcccgctc tcgcaccctg tcccagagca gcgagtctgg aactctttct tcggggcccc     1260

cggggcacac catggaggtc tcctgttgaa tggcccttgt tgccctagag tgggacccag     1320

ccctcacctc ccccagagct aacctgggag gtgctgaagg ggcattgggc caccgtaagc     1380

aagggaaaaa gggcagatca tgcggggaga tgaccttgat ctttgattgc taccctaacc     1440

ttgaccttta acccgtgatt ccccccagct cctggaagag atgtcctaat atctcttagg     1500

gacccagacc cctaaattct cctcctcccc cattttgatg ttaaggtgga gagggcatat     1560

gcatcctctg tcctgatcta ggtgtctata gctgaggggt aagaggttgt tgtagttgtc     1620

ctggtgcctc catcagactc tccctacttg tcccatattt gcaaggggag gggatttggg     1680

gctggggctc cattcaccaa agctgaggtg gcttctcatt aaccctttag gactctgaag     1740

ggtatggacc tacgtgaatg tgtgtcaggg ggagacttgc tggtgggtta gtggtcctca     1800

ggatgtgata gaaacatcca gtgtaaaaag gaagttggaa tgggagttgg cgggcagtga     1860

acgagtgtgg ggaaggattg gtgctggggc aacaggaagg ggcctggggc cgtttggctg     1920

cactaacttt ggtagctcag tgtgcatcta gagtgggact ggggagggag ctaagcttgg     1980

gctgggctgc ttggggcttg gcatagggtg gaaagggcta ccctggggct ctgaccacac     2040

tgtagtatgt gtggagggtg ccctcccgtc tcccacaact tctgctataa caataaactg     2100

tagaggaatc tgagtaccgt taaaaaaaaa aaaaaaaaaa aa                        2142


<210>  502
<211>  2033
<212>  DNA
<213>  homo sapiens

<400>  502
cggccccccg cattccccgc ccccacctcc ccgccttgtt gtccaacttc tcccggagca       60

gccggagagc aggcgtcggg acgcagcaaa gagaggagag gccaccatgg cggagctgca      120

ggaggtgcag atcacagagg agaagccact gttgccagga cagacgcctg aggcggccaa      180

gactcactct gtggagacac catacggctc tgtcactttc actgtctatg gcacccccaa      240

acccaaacgc ccagcgatcc ttacctacca cgatgtggga ctcaactata aatcttgctt      300

ccagccactg tttcagttcg aggacatgca ggaaatcatt cagaactttg tgcgggttca      360

tgtggatgcc cctggaatgg aagagggagc ccctgtgttc cctttgggat atcagtaccc      420

atctctggac cagcttgcag acatgatccc ttgcgtcctg cagtacctaa atttctctac      480

aataattgga gttggtgttg gagctggagc ctacatcctg gcgagatatg ctcttaacca      540

cccggacact gttgaaggtc ttgtcctcat caacattgat cccaatgcca agggttggat      600

ggattgggca gcccacaagc taacaggcct cacctcttcc attccggaga tgatccttgg      660

acatcttttc agccaggaag agctctctgg aaattctgag ttgatacaaa agtacagaaa      720

tatcattaca catgcaccca acctggataa cattgaattg tactggaaca gctacaacaa      780

ccgccgagac ctgaactttg agcgtggagg tgatatcacc ctcaggtgtc ctgtgatgct      840

ggtggtagga gaccaagcac ctcatgaaga tgcagtggtg gaatgtaact caaaactgga      900

ccccacccag acctcgttcc tcaagatggc tgactccgga ggtcagcccc agctgactca      960

gccaggcaag ctgaccgagg ccttcaagta cttcctgcaa ggcatgggct acatggcctc     1020

atcctgcatg actcgcctgt cccggtctcg tacagcctct ctgaccagtg cagcatccgt     1080

tgatggcaac cggtcccgct ctcgcaccct gtcccagagc agcgagtctg gaactctttc     1140

ttcggggccc ccggggcaca ccatggaggt ctcctgttga atggcccttg ttgccctaga     1200

gtgggaccca gccctcacct cccccagagc taacctggga ggtgctgaag gggcattggg     1260

ccaccgtaag caagggaaaa agggcagatc atgcggggag atgaccttga tctttgattg     1320

ctaccctaac cttgaccttt aacccgtgat tccccccagc tcctggaaga gatgtcctaa     1380

tatctcttag ggacccagac ccctaaattc tcctcctccc ccattttgat gttaaggtgg     1440

agagggcata tgcatcctct gtcctgatct aggtgtctat agctgagggg taagaggttg     1500

ttgtagttgt cctggtgcct ccatcagact ctccctactt gtcccatatt tgcaagggga     1560

ggggatttgg ggctggggct ccattcacca aagctgaggt ggcttctcat taacccttta     1620

ggactctgaa gggtatggac ctacgtgaat gtgtgtcagg gggagacttg ctggtgggtt     1680

agtggtcctc aggatgtgat agaaacatcc agtgtaaaaa ggaagttgga atgggagttg     1740

gcgggcagtg aacgagtgtg gggaaggatt ggtgctgggg caacaggaag gggcctgggg     1800

ccgtttggct gcactaactt tggtagctca gtgtgcatct agagtgggac tggggaggga     1860

gctaagcttg ggctgggctg cttggggctt ggcatagggt ggaaagggct accctggggc     1920

tctgaccaca ctgtagtatg tgtggagggt gccctcccgt ctcccacaac ttctgctata     1980

acaataaact gtagaggaat ctgagtaccg ttaaaaaaaa aaaaaaaaaa aaa            2033


<210>  503
<211>  2100
<212>  DNA
<213>  homo sapiens

<400>  503
cggccccccg cattccccgc ccccacctcc ccgccttgtt gtccaacttc tcccggagca       60

gccggagagc aggcgtcggg acgcagcaaa gagaggagag accccagagt cagaaggagt      120

gagaaccctg acccctaatc ccactgcatc cagccaatag gagcccagcc accatggcgg      180

agctgcagga ggtgcagatc acagaggaga agccactgtt gccaggacag acgcctgagg      240

cggccaagac tcactctgtg gagacaccat acggctctgt cactttcact gtctatggca      300

cccccaaacc caaacgccca gcgatcctta cctaccacga tgtgggactc aactataaat      360

cttgcttcca gccactgttt cagttcgagg acatgcagga aatcattcag aactttgtgc      420

gggttcatgt ggatgcccct ggaatggaag agggagcccc tgtgttccct ttgggatatc      480

agtacccatc tctggaccag cttgcagaca tgatcccttg cgtcctgcag tacctaaatt      540

tctctacaat aattggagtt ggtgttggag ctggagccta catcctggcg agatatgctc      600

ttaaccaccc ggacactgtt gaaggtcttg tcctcatcaa cattgatccc aatgccaagg      660

gttggatgga ttgggcagcc cacaagctaa caggcctcac ctcttccatt ccggagatga      720

tccttggaca tcttttcagc caggaagagc tctctggaaa ttctgagttg atacaaaagt      780

acagaaatat cattacacat gcacccaacc tggataacat tgaattgtac tggaacagct      840

acaacaaccg ccgagacctg aactttgagc gtggaggtga tatcaccctc aggtgtcctg      900

tgatgctggt ggtaggagac caagcacctc atgaagatgc agtggtggaa tgtaactcaa      960

aactggaccc cacccagacc tcgttcctca agatggctga ctccggaggt cagccccagc     1020

tgactcagcc aggcaagctg accgaggcct tcaagtactt cctgcaaggc atgggctaca     1080

tggcctcatc ctgcatgact cgcctgtccc ggtctcgtac agcctctctg accagtgcag     1140

catccgttga tggcaaccgg tcccgctctc gcaccctgtc ccagagcagc gagtctggaa     1200

ctctttcttc ggggcccccg gggcacacca tggaggtctc ctgttgaatg gcccttgttg     1260

ccctagagtg ggacccagcc ctcacctccc ccagagctaa cctgggaggt gctgaagggg     1320

cattgggcca ccgtaagcaa gggaaaaagg gcagatcatg cggggagatg accttgatct     1380

ttgattgcta ccctaacctt gacctttaac ccgtgattcc ccccagctcc tggaagagat     1440

gtcctaatat ctcttaggga cccagacccc taaattctcc tcctccccca ttttgatgtt     1500

aaggtggaga gggcatatgc atcctctgtc ctgatctagg tgtctatagc tgaggggtaa     1560

gaggttgttg tagttgtcct ggtgcctcca tcagactctc cctacttgtc ccatatttgc     1620

aaggggaggg gatttggggc tggggctcca ttcaccaaag ctgaggtggc ttctcattaa     1680

ccctttagga ctctgaaggg tatggaccta cgtgaatgtg tgtcaggggg agacttgctg     1740

gtgggttagt ggtcctcagg atgtgataga aacatccagt gtaaaaagga agttggaatg     1800

ggagttggcg ggcagtgaac gagtgtgggg aaggattggt gctggggcaa caggaagggg     1860

cctggggccg tttggctgca ctaactttgg tagctcagtg tgcatctaga gtgggactgg     1920

ggagggagct aagcttgggc tgggctgctt ggggcttggc atagggtgga aagggctacc     1980

ctggggctct gaccacactg tagtatgtgt ggagggtgcc ctcccgtctc ccacaacttc     2040

tgctataaca ataaactgta gaggaatctg agtaccgtta aaaaaaaaaa aaaaaaaaaa     2100


<210>  504
<211>  1868
<212>  DNA
<213>  homo sapiens

<400>  504
ggaagcgagg gtgcggcgca atccggagag gacgccagga cgacgcccga gttccctttc       60

aggctagaac tcttcctttt tctagcttgg ggtagaaggc ggagccggag ccccggaacc      120

cccgccctcg gggtgcgagg cggcagcagg gccgtcccct acatttgcat agcccctggg      180

acgtggcgct gcacccaagc ctcttctcag ttggagggaa ctccaagtcc cacagtgcca      240

cggggtgggg tgcgtcactt tcgctgcgtt ggaggctgag gagaattgag cctgggaggc      300

gggtccggag agggctatgg aaagccgccg gcggggaatc ccggccgtag agggacagtg      360

gataggtgcc cgaggcctac agctggcctg gggctcgtgt ctgggcttcg gacgttgggg      420

cccggtggcc caccctttcc gtagttgtcc caaatggagc tggaattgga tgctggtgac      480

caagacctgc tggccttcct gctagaggaa agtggagatt tggggacggc acccgatgag      540

gccgtgaggg ccccactgga ctgggcgctg ccgctttctg aggtaccgag cgactgggaa      600

gtagatgatt tgctgtgctc cctgctgagt cccccagcgt cgttgaacat tctcagctcc      660

tccaacccct gccttgtcca ccatgaccac acctactccc tcccacggga aactgtctct      720

atggatctag agagtgagag ctgtagaaaa gaggggaccc agatgactcc acagcatatg      780

gaggagctgg cagagcagga gattgctagg ctagtactga cagatgagga gaagagtcta      840

ttggagaagg aggggcttat tctgcctgag acacttcctc tcactaagac agaggaacaa      900

attctgaaac gtgtgcggag gaagattcga aataaaagat ctgctcaaga gagccgcagg      960

aaaaagaagg tgtatgttgg gggtttagag agcagggtct tgaaatacac agcccagaat     1020

atggagcttc agaacaaagt acagcttctg gaggaacaga atttgtccct tctagatcaa     1080

ctgaggaaac tccaggccat ggtgattgag atatcaaaca aaaccagcag cagcagcacc     1140

tgcatcttgg tcctactagt ctccttctgc ctcctccttg tacctgctat gtactcctct     1200

gacacaaggg ggagcctgcc agctgagcat ggagtgttgt cccgccagct tcgtgccctc     1260

cccagtgagg acccttacca gctggagctg cctgccctgc agtcagaagt gccgaaagac     1320

agcacacacc agtggttgga cggctcagac tgtgtactcc aggcccctgg caacacttcc     1380

tgcctgctgc attacatgcc tcaggctccc agtgcagagc ctcccctgga gtggccattc     1440

cctgacctct tctcagagcc tctctgccga ggtcccatcc tccccctgca ggcaaatctc     1500

acaaggaagg gaggatggct tcctactggt agcccctctg tcattttgca ggacagatac     1560

tcaggctaga tatgaggata tgtggggggt ctcagcagga gcctgggggg ctccccatct     1620

gtgtccaaat aaaaagcggt gggcaagggc tggccgcagc tcctgtgccc tgtcaggacg     1680

actgagggct caaacacacc acacttaatg gctttctggg tcttttattt gtacccatgt     1740

gtctgtcaca ccatgaatgt acctggggaa atcaactgac ctccctgaac atttcacgca     1800

gtcagggaac aggtgaggaa agaaataaat aagtgattct aatgctgcct aaaaaaaaaa     1860

aaaaaaaa                                                              1868


<210>  505
<211>  3831
<212>  DNA
<213>  homo sapiens

<400>  505
gggtcgtcag ggcgacgaaa aaggggaagg ggtgctgggc ctggcgggca aactaaggct       60

gcggaccgtt gggcggttcc gcggggcgtt gtccggagag ctgcgaggcc ggggttccca      120

gggttcacgc cacactctag gaagtgcctg agctagtgag ctggccaacg agctccgcgg      180

gctgggacca tgggctgctt cttctccaag agacggaagg ctgacaagga gtcgcggccc      240

gagaacgagg aggagcggcc aaagcagtac agctgggatc agcgcgagaa ggttgatcca      300

aaagactaca tgttcagtgg actgaaggat gaaacagtag gtcgcttacc tgggacggta      360

gcaggacaac agtttctcat tcaagactgt gagaactgta acatctatat ttttgatcac      420

tctgctacag ttaccattga tgactgtact aactgcataa tttttctggg acccgtgaaa      480

ggcagcgtgt ttttccggaa ttgcagagat tgcaagtgca cattagcctg ccaacaattt      540

cgtgtgcgag attgtagaaa gctggaagtc tttttgtgtt gtgccactca acccatcatt      600

gagtcttcct caaatatcaa atttggatgt tttcaatggt actatcctga attagctttc      660

cagttcaaag atgcagggct aagtatcttc aacaatacat ggagtaacat tcatgacttt      720

acacctgtgt caggagaact caactggagc cttcttccag aagatgctgt ggttcaggac      780

tatgttccta tacctactac cgaagagctc aaagctgttc gtgtttccac agaagccaat      840

agaagcattg ttccaatatc ccggggtcag agacagaaga gcagcgatga atcatgctta      900

gtggtattat ttgctggtga ttacactatt gcaaatgcca gaaaactaat tgatgagatg      960

gttggtaaag gctttttcct agttcagaca aaggaagtgt ccatgaaagc tgaggatgct     1020

caaagggttt ttcgggaaaa agcacctgac ttccttcctc ttctgaacaa aggtcctgtt     1080

attgccttgg agtttaatgg ggatggtgct gtagaagtat gtcaacttat tgtaaacgag     1140

atattcaatg ggaccaagat gtttgtatct gaaagcaagg agacggcatc tggagatgta     1200

gacagcttct acaactttgc tgatatacag atgggaatat gaagtgcaat gtggaaccag     1260

gacttggtat taagcctttc ccaacttgtg aatatagaat ttgataatac acttttgtgt     1320

attagcaatg gtttttacta atgctaaaac ttttaaagtt tattttttaa taaattgttg     1380

agtattacat catttacttg aggttcaaaa ataattcatt ttaaattaag tagttttaat     1440

cagcttaaaa gctatttaac ccattttaat aagcttgcag ttttgtttct ctgcatatga     1500

tattcttatt agaaaacaga agtagctaaa agtttattat tttaatccta tttaaatgtt     1560

ctttcaaatc tctaataatt taaactttcc tcagtgctcc atgatacttt ttttgagact     1620

ccatatcatt gcttatttta cctttttcaa tttagaggga tttgttacta gtcgatcaat     1680

tagaatgaac ctatgcacat ttttatgtac acatatccag ttatataatt gcttcctagt     1740

tgcattatat ggcaaatgag attttgtaca tggagttgac ataatacttt gtaaattgaa     1800

ttttttaaag aaataggcat ttgataacca gcttggcaag taactctact aacagatgtt     1860

ggtatagcta tttaaagact acttcgtaag tagtatgatt atttgaataa attacacatt     1920

gtttagtttt ttaatacaac tgctatatga ctcttctgct tcctgataag aaaaggtata     1980

tgcaatgcta aaactgtaga agcccaatca ccagcagttt ttaaaaaggt gataactttt     2040

attagctctt gtgggctatc aagagaattg gaacaaaacc ttgtgacttt taggtaagaa     2100

ataggcatga tgataagcta tgcagattat taaaaagctt gatacatttg atttttcatt     2160

agatatgcca ttcatatcaa gtaatgttca agtatgataa aattattttg gttgctttaa     2220

agcactgttt cccaaatcta cctgatcata ataatttacc aggaagcaga ggagagctac     2280

ttgtttaaaa atccacattc ttggacccaa tcctcagatg cacggattca gtcttcaggg     2340

gaaactctgt tttaaggggt atgttgtaat ctaaagtaat tggttcagga ggtgtcaata     2400

ggttgaactt gtgagaaggc actgaatctg ccatccacat cacatatagc agctattatg     2460

aaatcagctt tcataggcct atttttaaaa ggaatctgaa atttaattct attttgataa     2520

aactaagact gaaaataacc acttgtaaac attcctatga ttgttactaa aatgtatttt     2580

catgtttaaa atgtttttgg atatttttgg gttaataact actacattga attgcatgtt     2640

aaggtgcaga aataatacat taaaagattt tcactttaaa ttaattagta atattgagcg     2700

ctcaccctgt gcgtggcctt gtgctaacca ttagcactgc atcatttcaa ttcttttata     2760

agggcattca atactacaaa atcaacatga tttcataagg tgcaaataaa agttggtgac     2820

agatttaata taattttgat cacaatttac aaatgatctt tgcaaatagt ggtcagacgg     2880

cattagtttt tcccttagtt aagctaaatt aaagggactc catcctgtta tgattatatt     2940

attattatta ttattattat ttttgaggtg gagtttcact cttgttgccc aagctggagt     3000

gcaatggcgc gatctcggct caccacaaca tccgcctcct gggttcaagc gattctcctg     3060

cctcagcctc ctgagtagct gggaatacag gcatgcgcca ctacacctgg ctaatttttg     3120

tatttttagt tgagatgggg tttttccacg ttggtcaggc tggtctcgaa ctcctgacct     3180

caggtgatcc gtccacctca gcctcccaaa gagctgggat tacaggtgtg agctaccgcg     3240

cctggccatg atgatattat taaacaccat tattcacatt tcaaataata acaatacttt     3300

ttgtttttca aaaataaaat gcaatgttat ataaagctat aaactaagtt ctttatgata     3360

tttgagcaac aactcaggaa tataacatat aagggagatg ttaatttaaa aatttccact     3420

acacttatta tctattaacc aaagcttaaa attttgtatt cttctgttag ataagacctt     3480

ttacccattt aatttgtctt taaggacagt catttggctt ctgaatgttt gaaacgattt     3540

taaaaaataa gtagtgctat ggttgtttct ataattctaa cctttgatag taatcagaat     3600

gtattacatt tcatttctga atagcttttg aatttatgaa aaattattaa caatgaaaaa     3660

ttggtaattt tattaagtta tatgtgttta aatattatat tagcttattt ctcttgcatt     3720

aatagtactg ctgtttttgt tttgcttctt tatatttatg tctagctttt atatgtaatt     3780

tatctagtgt ttataaaatg tgatttgtaa taaatgttgt taaaatgaaa a              3831


<210>  506
<211>  2211
<212>  DNA
<213>  homo sapiens

<400>  506
tgttcctccc ggcgtgctcc gcggctcttg gctcacagcc gtcccttcgc tggtgggaag       60

aagccgagat ggcggcagcc agcgctgggg caacccggct gctcctgctc ttgctgatgg      120

cggtagcagc gcccagtcga gcccggggca gcggctgccg ggccgggact ggtgcgcgag      180

gggctggggc ggaaggtcga gagggcgagg cctgtggcac ggtggggctg ctgctggagc      240

actcatttga gatcgatgac agtgccaact tccggaagcg gggctcactg ctctggaacc      300

agcaggatgg taccttgtcc ctgtcacagc ggcagctcag cgaggaggag cggggccgac      360

tccgggatgt ggcagccctg aatggcctgt accgggtccg gatcccaagg cgacccgggg      420

ccctggatgg cctggaagct ggtggctatg tctcctcctt tgtccctgcg tgctccctgg      480

tggagtcgca cctgtcggac cagctgaccc tgcacgtgga tgtggccggc aacgtggtgg      540

gcgtgtcggt ggtgacgcac cccgggggct gccggggcca tgaggtggag gacgtggacc      600

tggagctgtt caacacctcg gtgcagctgc agccgcccac cacagcccca ggccctgaga      660

cggcggcctt cattgagcgc ctggagatgg aacaggccca gaaggccaag aacccccagg      720

agcagaagtc cttcttcgcc aaatactggc acatcatcct ggggggggcc gtgttgctca      780

cagccctgcg tcctgctgcg ccagggcccg cgccaccgcc acaggaggcc tgatggatgt      840

acatcattcc cgtcgtcctg ttcctcatga tgtcaggagc gccagacacc gggggccagg      900

gtgggggtgg gggtgggggt ggtggtgggg gtagtggccg gtgagggccc aggctggtca      960

gcgtcccgtc ttgcacaccc aggggcctcc ctttctgctg gagtcccctg tgtcctcagc     1020

catcccaaga agggtttgct ggtccctcct ttccccccgt cccacgaggc cacctgggcc     1080

agccccttgt cctctgcctt ctgctggcag aggagcagct ggactggggc ctttggcaca     1140

gcagccggtg tctcctgcgc ccgcctcccc catggcccca tgcagcccca ggggcttccc     1200

ccctgcccat ggagtagagc ccgagatcct ggccactatg ccagttctga cctcgcatcc     1260

ccctaccccg agcccatgca gtctgggaac atgccgcctt ctctccagcc tctgtgcctt     1320

tgttccaggt ggtctcaccc tcctgtccct ggctgggcta ggtggtcctg tccaggctcc     1380

tgcagcgccc ccctcacttt gacactggac taggatgcag cctcccttct gtgtcccctt     1440

gagggtaccc tgggtcccct catcaggggc agaggcatga aagagtcggg gctggatggc     1500

cgggggcttc tgggcccgac gcctagtgca gcccctgggg tcgtggtttg acatttgtct     1560

gcctggtgca aacaaggaat ccttgccttt aaggtgacag gccctccaca ggcttccaga     1620

cttgaaggaa aaggtttaag aaagaaaaca aaaccaacag ttagtggagt caaagcccag     1680

acactgtaaa tagaaccccc tccaccaccc cccgccgccc agcatcctac ctggactgcg     1740

gtgctacgag ggcctgcggg cctttgctgt gtgccaccct ccctgtaagt ctatttaaaa     1800

acatcgacga tacattgaaa tgtgtgaacg ttttgaaaag ctacagcttc cagcagccaa     1860

aagcaactgt tgttttggca agacggtcct gatgtacaag cttgattgaa attcactgct     1920

cacttgatac gttattcaga aacccaagga atggctgtcc ccatcctcat gtggctgtgt     1980

ggagctcagc tgtgttgtgt ggcagtttat taaactgtcc cccagatcga cacgcagcta     2040

gcctcctgca ttgtatggtt ataaatagca ccctagtgag tgctgtcgtc cagtctctct     2100

tgggtgtggt ttgaatgatc tcgggatgca tgactaaaat ggaattacga tggcagatcg     2160

gaaacgcgtt tataaacaag tgatggtttg tgagtcgact gtcaagacca g              2211


<210>  507
<211>  2124
<212>  DNA
<213>  homo sapiens

<400>  507
tgttcctccc ggcgtgctcc gcggctcttg gctcacagcc gtcccttcgc tggtgggaag       60

aagccgagat ggcggcagcc agcgctgggg caacccggct gctcctgctc ttgctgatgg      120

cggtagcagc gcccagtcga gcccggggca gcggctgccg ggccgggact ggtgcgcgag      180

gggctggggc ggaaggtcga gagggcgagg cctgtggcac ggtggggctg ctgctggagc      240

actcatttga gatcgatgac agtgccaact tccggaagcg gggctcactg ctctggaacc      300

agcaggatgg taccttgtcc ctgtcacagc ggcagctcag cgaggaggag cggggccgac      360

tccgggatgt ggcagccctg aatggcctgt accgggtccg gatcccaagg cgacccgggg      420

ccctggatgg cctggaagct ggtggctatg tctcctcctt tgtccctgcg tgctccctgg      480

tggagtcgca cctgtcggac cagctgaccc tgcacgtgga tgtggccggc aacgtggtgg      540

gcgtgtcggt ggtgacgcac cccgggggct gccggggcca tgaggtggag gacgtggacc      600

tggagctgtt caacacctcg gtgcagctgc agccgcccac cacagcccca ggccctgaga      660

cggcggcctt cattgagcgc ctggagatgg aacaggccca gaaggccaag aacccccagg      720

agcagaagtc cttcttcgcc aaatactgga tgtacatcat tcccgtcgtc ctgttcctca      780

tgatgtcagg agcgccagac accgggggcc agggtggggg tgggggtggg ggtggtggtg      840

ggggtagtgg ccggtgaggg cccaggctgg tcagcgtccc gtcttgcaca cccaggggcc      900

tccctttctg ctggagtccc ctgtgtcctc agccatccca agaagggttt gctggtccct      960

cctttccccc cgtcccacga ggccacctgg gccagcccct tgtcctctgc cttctgctgg     1020

cagaggagca gctggactgg ggcctttggc acagcagccg gtgtctcctg cgcccgcctc     1080

ccccatggcc ccatgcagcc ccaggggctt cccccctgcc catggagtag agcccgagat     1140

cctggccact atgccagttc tgacctcgca tccccctacc ccgagcccat gcagtctggg     1200

aacatgccgc cttctctcca gcctctgtgc ctttgttcca ggtggtctca ccctcctgtc     1260

cctggctggg ctaggtggtc ctgtccaggc tcctgcagcg cccccctcac tttgacactg     1320

gactaggatg cagcctccct tctgtgtccc cttgagggta ccctgggtcc cctcatcagg     1380

ggcagaggca tgaaagagtc ggggctggat ggccgggggc ttctgggccc gacgcctagt     1440

gcagcccctg gggtcgtggt ttgacatttg tctgcctggt gcaaacaagg aatccttgcc     1500

tttaaggtga caggccctcc acaggcttcc agacttgaag gaaaaggttt aagaaagaaa     1560

acaaaaccaa cagttagtgg agtcaaagcc cagacactgt aaatagaacc ccctccacca     1620

ccccccgccg cccagcatcc tacctggact gcggtgctac gagggcctgc gggcctttgc     1680

tgtgtgccac cctccctgta agtctattta aaaacatcga cgatacattg aaatgtgtga     1740

acgttttgaa aagctacagc ttccagcagc caaaagcaac tgttgttttg gcaagacggt     1800

cctgatgtac aagcttgatt gaaattcact gctcacttga tacgttattc agaaacccaa     1860

ggaatggctg tccccatcct catgtggctg tgtggagctc agctgtgttg tgtggcagtt     1920

tattaaactg tcccccagat cgacacgcag ctagcctcct gcattgtatg gttataaata     1980

gcaccctagt gagtgctgtc gtccagtctc tcttgggtgt ggtttgaatg atctcgggat     2040

gcatgactaa aatggaatta cgatggcaga tcggaaacgc gtttataaac aagtgatggt     2100

ttgtgagtcg actgtcaaga ccag                                            2124


<210>  508
<211>  5946
<212>  DNA
<213>  homo sapiens

<400>  508
tttttttttt ttttttgctt aaaaaaaagc catgacggct ctcccacaat tcatcttccc       60

tgcgccatct ttgtattatt tctaatttat tttggatgtc aaaaggcact gatgaagata      120

ttttctctgg agtctccttc tttctaaccc ggctctcccg atgtgaaccg agccgtcgtc      180

cgcccgccgc cgccgccgcc gccgccgccg cccgccccgc agcccaccat gtctcgccgc      240

aagcaaggca aaccccagca cttaagcaaa cgggaattct cgcccgagcc tcttgaagcc      300

attcttacag atgatgaacc agaccacggc ccgttgggag ctccagaagg ggatcatgac      360

ctcctcacct gtgggcagtg ccagatgaac ttcccattgg gggacattct tatttttatc      420

gagcacaaac ggaaacaatg caatggcagc ctctgcttag aaaaagctgt ggataagcca      480

ccttcccctt caccaatcga gatgaaaaaa gcatccaatc ccgtggaggt tggcatccag      540

gtcacgccag aggatgacga ttgtttatca acgtcatcta gaggaatttg ccccaaacag      600

gaacacatag cagataaact tctgcactgg aggggcctct cctcccctcg ttctgcacat      660

ggagctctaa tccccacgcc tgggatgagt gcagaatatg ccccgcaggg tatttgtaaa      720

gatgagccca gcagctacac atgtacaact tgcaaacagc cattcaccag tgcatggttt      780

ctcttgcaac acgcacagaa cactcatgga ttaagaatct acttagaaag cgaacacgga      840

agtcccctga ccccgcgggt tggtatccct tcaggactag gtgcagaatg tccttcccag      900

ccacctctcc atgggattca tattgcagac aataacccct ttaacctgct aagaatacca      960

ggatcagtat cgagagaggc ttccggcctg gcagaagggc gctttccacc cactcccccc     1020

ctgtttagtc caccaccgag acatcacttg gacccccacc gcatagagcg cctgggggcg     1080

gaagagatgg ccctggccac ccatcacccg agtgcctttg acagggtgct gcggttgaat     1140

ccaatggcta tggagcctcc cgccatggat ttctctagga gacttagaga gctggcaggg     1200

aacacgtcta gcccaccgct gtccccaggc cggcccagcc ctatgcaaag gttactgcaa     1260

ccattccagc caggtagcaa gccgcccttc ctggcgacgc cccccctccc tcctctgcaa     1320

tccgcccctc ctccctccca gcccccggtc aagtccaagt catgcgagtt ctgcggcaag     1380

acgttcaaat ttcagagcaa cctggtggtg caccggcgca gccacacggg cgagaagccc     1440

tacaagtgca acctgtgcga ccacgcgtgc acccaggcca gcaagctgaa gcgccacatg     1500

aagacgcaca tgcacaaatc gtcccccatg acggtcaagt ccgacgacgg tctctccacc     1560

gccagctccc cggaacccgg caccagcgac ttggtgggca gcgccagcag cgcgctcaag     1620

tccgtggtgg ccaagttcaa gagcgagaac gaccccaacc tgatcccgga gaacggggac     1680

gaggaggaag aggaggacga cgaggaagag gaagaagagg aggaagagga ggaggaggag     1740

ctgacggaga gcgagagggt ggactacggc ttcgggctga gcctggaggc ggcgcgccac     1800

cacgagaaca gctcgcgggg cgcggtcgtg ggcgtgggcg acgagagccg cgccctgccc     1860

gacgtcatgc agggcatggt gctcagctcc atgcagcact tcagcgaggc cttccaccag     1920

gtcctgggcg agaagcataa gcgcggccac ctggccgagg ccgagggcca cagggacact     1980

tgcgacgaag actcggtggc cggcgagtcg gaccgcatag acgatggcac tgttaatggc     2040

cgcggctgct ccccgggcga gtcggcctcg gggggcctgt ccaaaaagct gctgctgggc     2100

agccccagct cgctgagccc cttctctaag cgcatcaagc tcgagaagga gttcgacctg     2160

cccccggccg cgatgcccaa cacggagaac gtgtactcgc agtggctcgc cggctacgcg     2220

gcctccaggc agctcaaaga tcccttcctt agcttcggag actccagaca atcgcctttt     2280

gcctcctcgt cggagcactc ctcggagaac gggagtttgc gcttctccac accgcccggg     2340

gagctggacg gagggatctc ggggcgcagc ggcacgggaa gtggagggag cacgccccat     2400

attagtggtc cgggcccggg caggcccagc tcaaaagagg gcagacgcag cgacacttgt     2460

gagtactgtg ggaaagtctt caagaactgt agcaatctca ctgtccacag gagaagccac     2520

acgggcgaaa ggccttataa atgcgagctg tgcaactatg cctgtgccca gagtagcaag     2580

ctcaccaggc acatgaaaac gcatggccag gtggggaagg acgtttacaa atgtgaaatt     2640

tgtaagatgc cttttagcgt gtacagtacc ctggagaaac acatgaaaaa atggcacagt     2700

gatcgagtgt tgaataatga tataaaaact gaatagaggt atattaatac ccctccctca     2760

ctcccacctg acaccccctt tttcaccact ccccttcccc atcgccctcc agccccactc     2820

cctgtaggat ttttttctag tcccatgtga tttaaacaaa caaacaaaca aacagaagta     2880

acgaagctaa gaatatgaga gtgcttgtca ccagcacacc tgtttttttt ctttttcttt     2940

ttcttttttc tttttccttt tttttttttt tcctttatgt tctcaccgtt tgaatgcatg     3000

atctgtatgg ggcaatacta ttgcatttta cgcaaacttt gagcctttct cttgtgcaat     3060

aatttacatg ttgtgtatgt ttttttttaa acttagacag catgtatggt atgttatggc     3120

tattttaaat tgtccctaat tcgttgctga gcaaacatgt tgctgtttcc agttccgttc     3180

tgagagaaaa agagagagag agagaaaaag accatgctgc atacattctg taatacatat     3240

catgtacagt tttattttat aacgtgagga ggaaaaacag tctttggatt aaccctctat     3300

agacagaata gatagcactg aaaaaaaatc tctatgagct aaatgtctgt ctctaaaggg     3360

ttaaatgtat caattggaaa ggaagaaaaa aggccttgaa ttgacaaatt aacagaaaaa     3420

cagaacaagt ttattctatc atttggtttt aaaatatgag tgccttggat ctattaaaac     3480

cacatcgatg gttctttcta cttgttataa acttgtagct taattcagca ttgggtgagg     3540

taataaacct taggaactag catataattc tatattgtat ttctcacaac aatggctacc     3600

taaaaagatg acccattatg tcctagttaa tcatcatttt tcctttagtt taattttata     3660

aacaaaactg attataccag tataaaagct actttgctcc tggtgagagc ttaaaagaaa     3720

tgggctgttt tgcccaaagt tttatttttt ttaaacaatg attaaattga atgtgtaatg     3780

tgcaaaagcc ctggaacgca attaaataca ctagtaagga gttcatttta tgaagatatt     3840

tgctttaata atgtcttttt aaaaatactg gcaccaaaag aaatagatcc agatctactt     3900

ggttgtcaag tggacaatca aatgataaac tttaagacct tgtataccat attgaaagga     3960

agaggctgac aataaggttt gacagagggg aacagaagaa aataatatga tttattagca     4020

caacgtggta ctatttgcca tttaaaacta gaacaggtat ataagctaat attgatacaa     4080

tgatgattaa ctatgaattc ttaagacttg catttaaatg tgacattctt aaaaaaagaa     4140

gagaaagaat tttaagagta gcagtatata tgtctgtgct ccctaaaagt tgtacttcat     4200

ttcttttcca tacactgtgt gctatttgtg ttaacatgga agaggattca ttgtttttat     4260

ttttattttt ttaatttttt cttttttatt aagctagcat ctgccccagt tggtgttcaa     4320

atagcacttg actctgcctg tgatatctgt atcttttctc taatcagaga tacagaggtt     4380

gagtataaaa taaacctgct cagataggac aattaagtgc actgtacaat tttcccagtt     4440

tacaggtcta tacttaaggg aaaagttgca agaatgctga aaaaaaattg aacacaatct     4500

cattgaggag cattttttaa aaactaaaaa aaaaaaaact ttgccagcca tttacttgac     4560

tattgagctt acttacttgg acgcaacatt gcaagcgctg tgaatggaaa cagaatacac     4620

ttaacataga aatgaatgat tgctttcgct tctacagtgc aaggattttt ttgtacaaaa     4680

cttttttaaa tataaatgtt aagaaaaatt ttttttaaaa aacacttcat tatgtttagg     4740

ggggaactgc attttagggt tccattgtct tggtggtgtt acaagacttg ttatccattt     4800

aaaaatggta gtggaaattc tatgccttgg atacacaccg ctcttcaggt tgtaaaaaaa     4860

aaaaacatac attggggaaa ggtttaagat tatatagtac ttaaatatag gaaaatgcac     4920

actcatgttg attcctatgc taaaatacat ttatggtctt ttttctgtat ttctagaatg     4980

gtatttgaat taaatgttca tctagtgtta ggcactatag tatttatatt gaagcttgta     5040

tttttaactg ttgcttgttc tcttaaaagg tatcaatgta ccttttttgg tagtggaaaa     5100

aaaaaagaca ggctgccaca gtatattttt ttaatttggc aggataatat agtgcaaatt     5160

atttgtatgc ttcaaaaaaa aaaaaaagag agaaacaaaa aagtgtgaca ttacagatga     5220

gaagccatat aatggcggtt tgggggagcc tgctagaatg tcacatggat ggctgtcata     5280

ggggttgtac atatcctttt ttgttccttt ttcctgctgc catactgtat gcagtactgc     5340

aagctaataa cgttggtttg ttatgtagtg tgctttttgt ccctttcctt ctatcaccct     5400

acattccagc atcttacctt catatgcagt aaaagaaaga aagaaaaaaa aaggaaaaaa     5460

aaaaaaaaac caatgttttg cagttttttt cattgccaaa aactaaatgg tgctttatat     5520

ttagattgga aagaatttca tatgcaaagc atattaaaga gaaagcccgc tttagtcaat     5580

acttttttgt aaatggcaat gcagaatatt ttgttattgg ccttttctat tcctgtaatg     5640

aaagctgttt gtcgtaactt gaaattttat cttttactat gggagtcact atttattatt     5700

gcttatgtgc cctgttcaaa acagaggcac ttaatttgat cttttatttt tctttgtttt     5760

tatttttttt tttatttaga tgaccaaagg tcattacaac ctggcttttt attgtatttg     5820

tttctggtct ttgttaagtt ctattggaaa aaccactgtc tgtgtttttt tggcagttgt     5880

ctgcattaac ctgttcatac acccattttg tccctttatt gaaaaaataa aaaaaattaa     5940

agtaca                                                                5946


<210>  509
<211>  2358
<212>  DNA
<213>  homo sapiens

<400>  509
tttttttttt ttttttgctt aaaaaaaagc catgacggct ctcccacaat tcatcttccc       60

tgcgccatct ttgtattatt tctaatttat tttggatgtc aaaaggcact gatgaagata      120

ttttctctgg agtctccttc tttctaaccc ggctctcccg atgtgaaccg agccgtcgtc      180

cgcccgccgc cgccgccgcc gccgccgccg cccgccccgc agcccaccat gtctcgccgc      240

aagcaaggca aaccccagca cttaagcaaa cgggaattct cgcccgagcc tcttgaagcc      300

attcttacag atgatgaacc agaccacggc ccgttgggag ctccagaagg ggatcatgac      360

ctcctcacct gtgggcagtg ccagatgaac ttcccattgg gggacattct tatttttatc      420

gagcacaaac ggaaacaatg caatggcagc ctctgcttag aaaaagctgt ggataagcca      480

ccttcccctt caccaatcga gatgaaaaaa gcatccaatc ccgtggaggt tggcatccag      540

gtcacgccag aggatgacga ttgtttatca acgtcatcta gaggaatttg ccccaaacag      600

gaacacatag cagataaact tctgcactgg aggggcctct cctcccctcg ttctgcacat      660

ggagctctaa tccccacgcc tgggatgagt gcagaatatg ccccgcaggg tatttgtaaa      720

gatgagccca gcagctacac atgtacaact tgcaaacagc cattcaccag tgcatggttt      780

ctcttgcaac acgcacagaa cactcatgga ttaagaatct acttagaaag cgaacacgga      840

agtcccctga ccccgcgggt tcttcacaca cccccattcg gcgtagtacc cagagagctc      900

aagatgtgtg gcagttttcg gatggaagct cgagagccct taagttctga gaaaatttga      960

agcccccagg ggtggggtgg acgcgtgccg cccagtcgac gtcagcgtgg tctgtcatcc     1020

tgctagtttg tgatgttttc tgacagtagc ctccaagaag ccgttgtgcg aagacagagt     1080

cctgcagagt ccttccagcc taggcctgca gcgccatttt atttatattt tttaataaaa     1140

agtaaaaaca aaaaaacaga cccacattgg aacagtgaat cagtcccata gagagggccc     1200

gtggaccatc gctgtcatga gtgatgccct ggcccttctg aaaccagcca acctaattac     1260

ctgtattgtg gaaatgcgca tgagtcccca accccttgtt tctatacatt ctatgttgtc     1320

ttttaaaaag tgtgcttaac attgacacaa taaatgttgg agctttaggt ggtgtttgct     1380

tgttctttaa tttttaatgc ttataagaca atgaggctgc ttatgatttt gtacttctgt     1440

acctgtttcc tacagacacc catcgggtgg gtaggaggaa cagatttgag aaatgggcag     1500

gagatgtagg aggggaacta ggttaccgct tatcagatgg cataaatttt caaggagaat     1560

caaaatgcaa aacttgggaa taaatcatag caatatcata attaatgtag tagtaatatt     1620

gctgtttatt aatgctgaag tgtggttttc ctaactgtct gacttataat ttgcatacca     1680

ttaaataatg cataatatgg cacgccgaat cctgtttttc aaatatatgc ttttggtggc     1740

taccatgcag gatttgaatt tgtcttttaa tttagcttag gaaagaacat cactgggcga     1800

gcggtaaatc ctaaagaagg tgataaatgt cagtagtttc ttattaaata ttctaatttt     1860

aggttcccaa accttcagga aatatatctt aatgcagaca aacaaacata aaacttcttt     1920

agtacttaca tcaggaaatt tggggcagat tttagagggg ggaaattata ggaggaaaga     1980

agttcacatc agaacagaca atcacagcaa tgctctattc cttagaaatt agtgccacaa     2040

ataagttaca tctacaaaca ggtggtaaaa attctttctg gcccagttaa tttgcacaga     2100

acttttctca gtttggtatt ttttactgct tggagatcca gaagagaatt agaaacaaca     2160

tagcaaatta aaataggttt gtcaataata gagctcagac acctgtgtgc tgtagattca     2220

catacaggcc gtgaacctaa gtggggaaaa tcctacctat ccaccttctg gctagattac     2280

ctagcttagt gaaaagatag ccaaataatt ggcatgtgaa ttatttcctg cttattcata     2340

ataaataatg actgtcta                                                   2358


<210>  510
<211>  5265
<212>  DNA
<213>  homo sapiens

<400>  510
acgcgggcgg gtgccgaggg gaggggagtg gcggcggcgg cgggcggctc ccgcttcagc       60

ctcggcagtg gcgtcggcga cggcggtgtc gaggcagccg ccagcgttcg gccaagtgtc      120

agccggcagc gacggcgcta gagctgggag ctggggacgc gcgcgccgga ccttccacag      180

cctccgccca gagcctgagg cgccggggcc gggggagccg gggggcgggc gggcgagcgg      240

gccgggggga gggtggggga tggcgcggac cctgcggccg tccccgctgt gtcctggagg      300

cggcaaagca caactttcct ccgcttctct cctcggagcc gggctcctgc tgcagccccc      360

gacgccacct ccgctgctgc tgctgctctt cccgctgctg ctcttctcca ggctctgtgg      420

tgccttagct ggaccaatta ttgtggagcc acatgtcaca gcagtatggg gaaagaatgt      480

ttcattaaag tgtttaattg aagtaaatga aaccataaca cagatttcat gggagaagat      540

acatggcaaa agttcacaga ctgttgcagt tcaccatccc caatatggat tctctgttca      600

aggagaatat cagggaagag tcttgtttaa aaattactca cttaatgatg caacaattac      660

tctgcataac ataggattct ctgattctgg aaaatacatc tgcaaagctg ttacattccc      720

gcttggaaat gcccagtcct ctacaactgt aactgtgtta gttgaaccca ctgtgagcct      780

gataaaaggg ccagattctt taattgatgg aggaaatgaa acagtagcag ccatttgcat      840

cgcagccact ggaaaacccg ttgcacatat tgactgggaa ggtgatcttg gtgaaatgga      900

atccactaca acttcttttc caaatgaaac ggcaacgatt atcagccagt acaagctatt      960

tccaaccaga tttgctagag gaaggcgaat tacttgtgtt gtaaaacatc cagccttgga     1020

aaaggacatc cgatactctt tcatattaga catacagtat gctcctgaag tttcggtaac     1080

aggatatgat ggaaattggt ttgtaggaag aaaaggtgtt aatctcaaat gtaatgctga     1140

tgcaaatcca ccacccttca aatctgtgtg gagcaggttg gatggacaat ggcctgatgg     1200

tttattggct tcagacaata ctcttcattt tgtccatcca ttgactttca attattctgg     1260

tgtttatatc tgtaaagtga ccaattccct tggtcaaaga agtgaccaaa aagtcatcta     1320

catttcagat cctcctacta ctaccaccct tcagcctaca attcagtggc atccctcaac     1380

tgctgacatc gaggatctag caacagaacc taaaaaattg cccttcccat tgtcaacttt     1440

ggcaacaatt aaggatgaca caattgccac gatcattgct agtgtagtgg gtggggctct     1500

cttcatagta cttgtaagtg ttttggctgg aatattctgc tataggagaa gacggacgtt     1560

tcgtggagac tactttgcca agaactacat tccaccatca gatatgcaaa aagaatcaca     1620

aatagatgtt cttcaacaag atgagcttga ttcttaccca gacagtgtaa aaaaagaaaa     1680

caaaaatcca gtgaacaatc taatacgtaa agactattta gaagagcctg aaaaaactca     1740

gtggaacaat gtagaaaatc tcaataggtt tgaaagacca atggattatt atgaagatct     1800

aaaaatggga atgaagtttg tcagtgatga acattatgat gaaaacgaag atgacttagt     1860

ttcacatgta gatggttccg taatttccag gagggagtgg tatgtttagc aaccactgaa     1920

tgtgacttaa ctatgtacaa tgttcattca cactagttga tcattttcag attgttcata     1980

ctttttcttg aggaagaata agctttttca agttgatttt caagcttact ttttatattc     2040

taatctgaca aatgaaaatg taaaatctga gttcagtgta tctaagctgc tttacaattt     2100

tttttcaatg ctgtactact gtctcaagat ttaaatttta atgcagagta ctttattggt     2160

gtgaggcaca caggtaagaa gaaatgtcaa cattaaatgt atgacttact tggtacaaaa     2220

attttttaaa aagggaacta ccttgacatt gtgtattaaa tgtttaccta agactataat     2280

ctcaagtatg atgtttgttt aacatatacc tctcaaaatt tatcaccact caatgacact     2340

gcatcaaaat tgactataaa actaattcaa gaaatattta tatatatttt ttaatataca     2400

aaaaatattt agcctgatgg aatggctttc cttttcaaac attattttct aagtttctat     2460

acaaatgaaa tctttacctc tgcatattaa tgagccttgc cataattact gtagagtggc     2520

ttttcaaaga tattttgttg cactaaaact gtggtagtaa actcagtgaa catgatgtgt     2580

ggaagagcat aattagctgg tcaatatttt tgtccaaaat acctgcaaga gtaataaaat     2640

acataccttt caaacatgat aattattagt tttttttttt cctttctgga acatggattt     2700

tggtacatta gcagtagcct tattttaatg ctttatgtcc taaacatact aatagaaatg     2760

aaaagacgca gagagagcat ttcggaatac tgaagtacta gttttagaaa tgagactttc     2820

agccaacaat ctatagaaag aattttatgg accatcttgt tttagttatt taatgttgat     2880

gttgttcaaa tgggtaaatg tacagaaaga aaattttaga gtaaacttgg aactttggat     2940

ataactagaa aaaactagat tatagaatta gtcggtaaca cttgctaatg gacattggca     3000

ttcatctcct ttttcctcct aagtgtatgt atgtgtttta agatttctgt ttttacgatt     3060

aaaactggaa acatgaggtt ttttgttttt gtttttttac ataattacat atattccttc     3120

tgaatcattt atcttttgag aaagaaatgt tacctaaact tcaaatgtgc tttttgtttg     3180

tgaggtaatt aaattgcttc tacagtggag gcttacaaaa ttattgtgac aactattttg     3240

aagctgaaag gatagttttt ctattgctaa gtcatttgaa aaagtgacca ttttgccagt     3300

gaaatgaagt ggaagttagt aggagaatca taaattaaat atattatttt gttaataaaa     3360

aggcaaagta gtaggtactt tttaaaccct cccaaccagc cctttctcaa tattcatcaa     3420

atctaaaaca tttagggggc aaaattctaa catgttcatg gtatcttgca aatagtgaaa     3480

gctttattct gaaggattat aaactagttt tcttcatttt aactagcact attttgtgga     3540

aattagaaac ctcttttatt tctcttccca aaagtaatac ttattataag gctgtagtat     3600

caggttaagg atacagataa ataaagttca cttatatctt cttacaaatg tctgggtttt     3660

aatatggtta atcacttata tacaaatatt acaacttttt agtgcaagtt tttggaagaa     3720

aactttttga taaaacactg tgattgatgt gactttattt ttaatttaaa cgatgaggtg     3780

gccagaagaa agatgggtct aaaatttctc cccatgaaag atgtaaaact atggcttttt     3840

ttaaaatcaa aatttcatct tttaaaataa tggtttgaaa tactgtatgg atctgaacag     3900

aataatcaca tttaggattc tatataaatc tcaactggag tataatctga aggaaattag     3960

cagtgtattt taagaaatat atttcaaaaa tataaatact gattatgaac ttccttttac     4020

attgtggtta tttgtgcgat taggtttttt tgtttgtttc ttttgtgttt gtttggcggg     4080

agagggtgac ctggaaagcc acaagtgagt atttgacata ttctgtatcc ttaatccaat     4140

catttggcaa actaaaaggt ttctgtgttg taagaatctg atactagtgc ttaagacttt     4200

gggaagcatt gcactgttgt ttattagaac tttatgtata tttactgtac atagagactt     4260

gtttgaaaac atgaatagtc attaaataaa gacattgtta aattagtttt tgaataccag     4320

tgatattcat aactacttga caggtatata tgaaaattct actatcgtga aaaaaaatga     4380

atatttgtac tatttttggc catatttata tttatttctt tcatatggtt tgaactgttt     4440

tagcattttg taaattcact tgagagtttt ctttcatact ggttaaaata tttcaatgat     4500

ataatgaaga tgaatgcaac tcttattttt ctgccatttt ttattaaaat acattgaaac     4560

taaagtaggc tcggggttaa ctttaaaagt gatatttgag aagtgcttta gagttgaaag     4620

atttagtatt ttaccacgtg cctagtaggg ttctatttgc taactctaat attgaggaaa     4680

ctattaaggt tttcagtagt aagtgttgct tctaatagcc atatacagga aagttttata     4740

agataaccca cggctaaata ttttgcatta aggagctgta ggagtacagt gtataagtac     4800

agaaattgag agaaatgtag tcattttata tgtgaaaaca tctgatttga gtttttgata     4860

aatactgcta aaacacagta tatgaacaag taagaagttt atgtatgaaa gtaatcaatg     4920

taaaatataa gaaaggaata aatggtaccc attttgaatt tttaattcta ataggagagt     4980

agattgtaga ttgaattgtc tttcctgttt acttgttaat tagaaaatgc atccttcata     5040

aacagctcct ttctcaaatt ttttgtatat tgtgtttgtg tttgggtttt agtttgtacc     5100

cgcgctaagt tttggttttg ttgtgtttgg tgttttttgt tttgttttgt tttgttttgt     5160

tttttctttt ttaaccaacc tgtgtattag gtgttagccc caatagccat gcatgaaatc     5220

tttaaataaa agttaaaaaa gttctttaga ggcaaaaaaa aaaaa                     5265


<210>  511
<211>  4410
<212>  DNA
<213>  homo sapiens

<400>  511
gtgctcgggg gttccctggc cctttcggca ggggtaaaac aataagaggg ggcggtggca       60

aagggggcgg gacgtccgtg gtccttgtcg cacgtcgcag cgcctggcgc ccgggaagag      120

gtggttgtga ggcagacgaa ctcgcggctc tccggcttcc gaggcttccg agttgtcgga      180

ggaagggggc ggcgagcaat aagaacccgc cgcacccggt cctcagcgac tcttctgacc      240

tccgcgcgac gtacccgccg ccgccgttgg ctggagcatt tgacattgtg cagcaaagaa      300

atggttatgg agaagcccag tccgctgctt gtagggcggg agtttgtgag gcaatattat      360

actttgctga ataaagctcc ggaatattta cacaggtttt atggcaggaa ttcttcctat      420

gttcatggtg gagtagatgc tagtggaaag ccccaggaag ctgtttatgg ccaaaatgat      480

atacaccaca aagtattatc tctgaacttc agtgaatgtc atactaaaat tcgtcatgtg      540

gatgctcatg caaccttgag tgatggagta gttgtccagg tcatgggttt gctgtctaac      600

agtggacaac cagaaagaaa gtttatgcaa acctttgttc tggctcctga aggatctgtt      660

ccaaataaat tttatgttca caatgatatg tttcgttatg aagatgaagt gtttggtgat      720

tctgagcctg aacttgatga agaatcagaa gatgaagtag aagaggaaca agaagaaaga      780

caaccatctc ctgaacctgt gcaagaaaat gctaacagtg gttactatga agctcaccct      840

gtgactaatg gcatagagga gcctttggaa gaatcctctc atgaacctga acctgagcca      900

gaatctgaaa caaagactga agagctgaaa ccacaagtgg aggagaagaa cttagaagaa      960

ctagaggaga aatctactac tcctcctccg gcagaacctg tttctctgcc acaagaacca     1020

ccaaaggctt tctcctgggc ttcagtgacc agtaaaaacc tgcctcctag tggtactgtt     1080

tcttcctctg gaattccacc ccatgttaaa gcaccagtct cacagccaag agtcgaagct     1140

aaaccagaag ttcaatctca gccacctcgt gtgcgtgaac aacgacctag agaacgacct     1200

ggttttcctc ctagaggacc aagaccaggc agaggagata tggaacagaa tgactctgac     1260

aaccgtagaa taattcgcta tccagatagt catcaacttt ttgttggtaa cttgccacat     1320

gatattgatg aaaatgagct aaaggaattc ttcatgagtt ttggaaacgt tgtggaactt     1380

cgcatcaata ccaagggtgt tgggggaaag cttccaaatt ttggttttgt ggtttttgat     1440

gactctgaac cagttcagag aatcttaatt gcaaaaccga ttatgtttcg aggggaagta     1500

cgtttaaatg tggaagagaa aaaaacaaga gctgcaagag agcgagaaac cagaggtggt     1560

ggtgatgatc gcagggatat taggcgcaat gatcgaggtc ccggtggtcc acgtggaatt     1620

gtgggtggtg gaatgatgcg tgatcgtgat ggaagaggac ctcctccaag gggtggcatg     1680

gcacagaaac ttggctctgg aagaggaacc gggcaaatgg agggccgctt cacaggacag     1740

cgtcgctgaa gctccactgt tggcaaagtc ttggcagtgg tacattattc atcgtgtttg     1800

cattcttgtt aatttttttt ttggctttgg aatgtgacac agcctttttg atcatttctt     1860

tgatgtgaaa agcatctttg gttatcagtt aaattgaggt ggacattatt tccccaattt     1920

cacaacagga ttcacattgt taatttataa atctagactt ggagaattaa ggactgagaa     1980

atgaccatat cttaaactat ctacgacaaa gtgaacttaa aaggacatgc ccactgaatt     2040

caggtccttt gagtaaaaaa aaaatcttct gctgcacatt ttgtttaagt gttactgttt     2100

ctgcctgtta atgctgggaa cacaaatagt gcaatttgtg caattggaga atcttgcctt     2160

ttttcttggc tccccccaaa aatacaaacc aacagaaact tgttatgcac tcatcaaaat     2220

gtactaatgg gtactctgaa ctcattaaca ttgacatctg caacaggagg caacagggaa     2280

aaaatctcat cttcttttcc agtagaaaat agtttgtgaa atgatgaggg cattttatct     2340

gcttgctgtg accagcgtgt gtacacataa accttaacaa gactacaagt atattccaga     2400

aggaaatcat tttagttatg aactaaataa taaaaattag aacttcaaat gcgatggtct     2460

tgactattag accagattta gtagctccat atctaagatt tttctacctg cccctcttca     2520

gtacagggat ggctggctgc tcaacacact cctcctcccc ttttttcctt tctttaagct     2580

gtgtacagtg aaaattgtct ttactgtatt tttgttctct ggtaatgtaa taagcatgat     2640

ggtgccttct attaatacat cattccagtc ttgctggtaa ttttgtacag tatagtgtat     2700

gaattgctgt gctgcaaagc caaacagctg caaaatgttg aaaaatcatc gaaatgtata     2760

aaaattgcag tatctttaaa atcagtaaaa tggactagca tattatttat cttgttcttc     2820

agttaacaac tttgtgttct ctgtgggagg gagggagtcc tgtgtgtttg tggggagagg     2880

gaaggaggaa gtcagttatt tgagtaagcc tctagttgac ttttctctta gcctgaatgt     2940

ggacgttgaa acatatcact tcagggcttg gaaaagtcag tcaacttgac gtacattttt     3000

agtgacattt taaaagcagt cagattctat aaatggcaag taagcctgaa gtgaggatac     3060

tgcaattttc ggagaaaaga acagcagctc tttaagtgtt tgcattttct atttgggggg     3120

cagggaactg tcattcattt tgcacaattc ttgaactgat gtcagcaccc gagtggctcc     3180

tgaatttaag tctgggacga catcttttat ttttacatga atctttaaac aattctgtga     3240

gcaaagtttg tagctgctgg attattgtct gtctttatag caagttccag taaaccacaa     3300

gtatggcaaa gcttatccaa ttttatgctt ggagcagtca gtacatacca gtttctgatg     3360

tttcaggcag gagtggggta aataagtgtg accacttaaa gctgctcgtt agcatggaag     3420

acttctccat tctatctttg taaaacagac aagatatgca cttgacatag tagcaaattg     3480

gttctgaatt atgcaactgt ttgctattta gtaaactagc aaatgatgca tgtattttgt     3540

ttttcatgta ctgggcaata tgagtaaaat ctgtcccttt ttcccccttt gaatgaggtc     3600

ttccatgttt gagggaaagt cttgcactat tgcatatatt ttggggacac agattttcat     3660

agtttccatt tttggggggc ttaaggattt tttttttttc tgtttgaaac agttttatac     3720

tttctgatat agtacttgaa attcttacca gaaaattact ttggagtttt gaagccttta     3780

ttaatactac ttttaaagaa gcagttgttt tattgtcaat gttttttttc ccccaagcat     3840

attttcttgt atttctgttt ccatatatat atatatatat ataatttcca attcaggata     3900

ttgccctgcc atccatgaaa actgttctgg caccaaaagt aatgacaaat gttaagtgta     3960

ataatagaaa agtagagcaa agagccattc agcttcagtc tttacatacc atgaataaaa     4020

cattaaaaca tcatatggag aagtttacat ggtgattgtt cacctgcagt actgtggagt     4080

tttaacattt tgtcctcttt tcagtgaaac agagtaaaaa tattcatcta ccattactgt     4140

tatttgctga ttttgtttta ttttttgatg gtaatattct atccttatga cactattgca     4200

accaaattgg ctttaccatc ttggctttag taggtataga agacaatgga ttaccatctt     4260

tattgctgta atgtgttaag cattatatgc tagtagaatc tagtttaatt gtttcaggtg     4320

gaaagtattc tttgagtttc catattgaat gtgtttggac taaacaaaca ataaactact     4380

gatgtctgca gcatttatct atgtccctaa                                      4410


<210>  512
<211>  4275
<212>  DNA
<213>  homo sapiens

<400>  512
acattccatt cgcgctccgc ggcgcgaggc aatcgtccgg tgtgtgagcc cgggagccgg       60

aggtgtagcg gcagagacat tgttcttgcc ggctccctac ggtgccgtgt gtgcgtgaga      120

gaagaccagt ctttcctcta gcatttgaca ttgtgcagca aagaaatggt tatggagaag      180

cccagtccgc tgcttgtagg gcgggagttt gtgaggcaat attatacttt gctgaataaa      240

gctccggaat atttacacag gttttatggc aggaattctt cctatgttca tggtggagta      300

gatgctagtg gaaagcccca ggaagctgtt tatggccaaa atgatataca ccacaaagta      360

ttatctctga acttcagtga atgtcatact aaaattcgtc atgtggatgc tcatgcaacc      420

ttgagtgatg gagtagttgt ccaggtcatg ggtttgctgt ctaacagtgg acaaccagaa      480

agaaagttta tgcaaacctt tgttctggct cctgaaggat ctgttccaaa taaattttat      540

gttcacaatg atatgtttcg ttatgaagat gaagtgtttg gtgattctga gcctgaactt      600

gatgaagaat cagaagatga agtagaagag gaacaagaag aaagacaacc atctcctgaa      660

cctgtgcaag aaaatgctaa cagtggttac tatgaagctc accctgtgac taatggcata      720

gaggagcctt tggaagaatc ctctcatgaa cctgaacctg agccagaatc tgaaacaaag      780

actgaagagc tgaaaccaca agtggaggag aagaacttag aagaactaga ggagaaatct      840

actactcctc ctccggcaga acctgtttct ctgccacaag aaccaccaaa ggctttctcc      900

tgggcttcag tgaccagtaa aaacctgcct cctagtggta ctgtttcttc ctctggaatt      960

ccaccccatg ttaaagcacc agtctcacag ccaagagtcg aagctaaacc agaagttcaa     1020

tctcagccac ctcgtgtgcg tgaacaacga cctagagaac gacctggttt tcctcctaga     1080

ggaccaagac caggcagagg agatatggaa cagaatgact ctgacaaccg tagaataatt     1140

cgctatccag atagtcatca actttttgtt ggtaacttgc cacatgatat tgatgaaaat     1200

gagctaaagg aattcttcat gagttttgga aacgttgtgg aacttcgcat caataccaag     1260

ggtgttgggg gaaagcttcc aaattttggt tttgtggttt ttgatgactc tgaaccagtt     1320

cagagaatct taattgcaaa accgattatg tttcgagggg aagtacgttt aaatgtggaa     1380

gagaaaaaaa caagagctgc aagagagcga gaaaccagag gtggtggtga tgatcgcagg     1440

gatattaggc gcaatgatcg aggtcccggt ggtccacgtg gaattgtggg tggtggaatg     1500

atgcgtgatc gtgatggaag aggacctcct ccaaggggtg gcatggcaca gaaacttggc     1560

tctggaagag gaaccgggca aatggagggc cgcttcacag gacagcgtcg ctgaagctcc     1620

actgttggca aagtcttggc agtggtacat tattcatcgt gtttgcattc ttgttaattt     1680

tttttttggc tttggaatgt gacacagcct ttttgatcat ttctttgatg tgaaaagcat     1740

ctttggttat cagttaaatt gaggtggaca ttatttcccc aatttcacaa caggattcac     1800

attgttaatt tataaatcta gacttggaga attaaggact gagaaatgac catatcttaa     1860

actatctacg acaaagtgaa cttaaaagga catgcccact gaattcaggt cctttgagta     1920

aaaaaaaaat cttctgctgc acattttgtt taagtgttac tgtttctgcc tgttaatgct     1980

gggaacacaa atagtgcaat ttgtgcaatt ggagaatctt gccttttttc ttggctcccc     2040

ccaaaaatac aaaccaacag aaacttgtta tgcactcatc aaaatgtact aatgggtact     2100

ctgaactcat taacattgac atctgcaaca ggaggcaaca gggaaaaaat ctcatcttct     2160

tttccagtag aaaatagttt gtgaaatgat gagggcattt tatctgcttg ctgtgaccag     2220

cgtgtgtaca cataaacctt aacaagacta caagtatatt ccagaaggaa atcattttag     2280

ttatgaacta aataataaaa attagaactt caaatgcgat ggtcttgact attagaccag     2340

atttagtagc tccatatcta agatttttct acctgcccct cttcagtaca gggatggctg     2400

gctgctcaac acactcctcc tccccttttt tcctttcttt aagctgtgta cagtgaaaat     2460

tgtctttact gtatttttgt tctctggtaa tgtaataagc atgatggtgc cttctattaa     2520

tacatcattc cagtcttgct ggtaattttg tacagtatag tgtatgaatt gctgtgctgc     2580

aaagccaaac agctgcaaaa tgttgaaaaa tcatcgaaat gtataaaaat tgcagtatct     2640

ttaaaatcag taaaatggac tagcatatta tttatcttgt tcttcagtta acaactttgt     2700

gttctctgtg ggagggaggg agtcctgtgt gtttgtgggg agagggaagg aggaagtcag     2760

ttatttgagt aagcctctag ttgacttttc tcttagcctg aatgtggacg ttgaaacata     2820

tcacttcagg gcttggaaaa gtcagtcaac ttgacgtaca tttttagtga cattttaaaa     2880

gcagtcagat tctataaatg gcaagtaagc ctgaagtgag gatactgcaa ttttcggaga     2940

aaagaacagc agctctttaa gtgtttgcat tttctatttg gggggcaggg aactgtcatt     3000

cattttgcac aattcttgaa ctgatgtcag cacccgagtg gctcctgaat ttaagtctgg     3060

gacgacatct tttattttta catgaatctt taaacaattc tgtgagcaaa gtttgtagct     3120

gctggattat tgtctgtctt tatagcaagt tccagtaaac cacaagtatg gcaaagctta     3180

tccaatttta tgcttggagc agtcagtaca taccagtttc tgatgtttca ggcaggagtg     3240

gggtaaataa gtgtgaccac ttaaagctgc tcgttagcat ggaagacttc tccattctat     3300

ctttgtaaaa cagacaagat atgcacttga catagtagca aattggttct gaattatgca     3360

actgtttgct atttagtaaa ctagcaaatg atgcatgtat tttgtttttc atgtactggg     3420

caatatgagt aaaatctgtc cctttttccc cctttgaatg aggtcttcca tgtttgaggg     3480

aaagtcttgc actattgcat atattttggg gacacagatt ttcatagttt ccatttttgg     3540

ggggcttaag gatttttttt ttttctgttt gaaacagttt tatactttct gatatagtac     3600

ttgaaattct taccagaaaa ttactttgga gttttgaagc ctttattaat actactttta     3660

aagaagcagt tgttttattg tcaatgtttt ttttccccca agcatatttt cttgtatttc     3720

tgtttccata tatatatata tatatataat ttccaattca ggatattgcc ctgccatcca     3780

tgaaaactgt tctggcacca aaagtaatga caaatgttaa gtgtaataat agaaaagtag     3840

agcaaagagc cattcagctt cagtctttac ataccatgaa taaaacatta aaacatcata     3900

tggagaagtt tacatggtga ttgttcacct gcagtactgt ggagttttaa cattttgtcc     3960

tcttttcagt gaaacagagt aaaaatattc atctaccatt actgttattt gctgattttg     4020

ttttattttt tgatggtaat attctatcct tatgacacta ttgcaaccaa attggcttta     4080

ccatcttggc tttagtaggt atagaagaca atggattacc atctttattg ctgtaatgtg     4140

ttaagcatta tatgctagta gaatctagtt taattgtttc aggtggaaag tattctttga     4200

gtttccatat tgaatgtgtt tggactaaac aaacaataaa ctactgatgt ctgcagcatt     4260

tatctatgtc cctaa                                                      4275


<210>  513
<211>  4422
<212>  DNA
<213>  homo sapiens

<400>  513
gcggccgccg cgccgcgcac ccatggacgg cccggccatc atcacccagg tgaccaaccc       60

caaggaggac gagggccggt tgccgggcgc gggcgagaaa gcctcccagt gcaacgtcag      120

cttaaagaag cagaggagcc gcagcatcct tagctccttc ttctgctgct tccgtgatta      180

caatgtggag gcccctccac ccagcagccc cagtgtgctt ccgccactgg tggaggagaa      240

tggtgggctt cagaagccac cagctaagta ccttcttcca gaggtgacgg tgcttgacta      300

tggaaagaaa tgtgtggtca ttgatttaga tgaaacattg gtgcacagtt cgtttaagcc      360

tattagtaat gctgatttta ttgttccggt tgaaatcgat ggaactatac atcaggtgta      420

tgtgctgaag cggccacatg tggacgagtt cctccagagg atggggcagc tttttgaatg      480

tgtgctcttt actgccagct tggccaagta tgcagaccct gtggctgacc tcctagaccg      540

ctggggtgtg ttccgggccc ggctcttcag agaatcatgt gtttttcatc gtgggaacta      600

cgtgaaggac ctgagtcgcc ttgggcggga gctgagcaaa gtgatcattg ttgacaattc      660

ccctgcctca tacatcttcc atcctgagaa tgcagtgcct gtgcagtcct ggttcgatga      720

catgacggac acggagctgc tggacctcat ccccttcttt gagggcctga gccgggagga      780

cgacgtgtac agcatgctgc acagactctg caataggtag ccctggcctc tgcctgcctc      840

ccgcctgtgc actctggaac ctctggcctc aggggacctg cctgtcctca gctccctggg      900

agctgaaagt gaggatactc cgtgctccag gccacagggt gaatgtggcc atgcctacct      960

gttttgtttt tttaagaaca gaaacaacta ttttaaaaga actcttttaa gaaatttcat     1020

aaagggacat gcattttact gggtttgctt ttcttaaaac ataccaaaaa agaaaaaaat     1080

agaaaaaaaa aaaaaaaaag cttgatctct atcagacttc ctttcaactg tcctcccctc     1140

caagcagacc acctgtcccc ttctatccca gctcagagca gctgacccaa ctcagaatct     1200

ctttcctaca ggatgaagtg ccttttgaat gttattttaa gccgagagtt aatttttcta     1260

cacaacatat ttccagacat cttttagtct tttattgtct tagatactat aagaagatga     1320

acatgacaat tttctagaac ctggtagcgt gtgtgtgtgt ggcggggggt gctgagggag     1380

gggagtgagt cacaggagcc tgtcccccaa caggtgtgac tgctctgaca acctgtggca     1440

tgctgcaggg tcaggctcct gataggagga tttcatgact atgtcattgt ctccactcat     1500

ttttgaccca gtttggaatg tatctgcaat tgtgtggctc aacactttag gaaacaatag     1560

attattttat attattattt ctgatggtga caagtttgtc ttgaggtcac attttctcct     1620

tgaaaagtga catcctgtca cttctgctct cacactactg ccatacattt gtgttttttg     1680

ttgttattgt ttgggtagag cagttacaag aaaccctaaa acccttggat ataaaagaaa     1740

tctgtttatt gatttttaaa tctttccttt ccaaaagctg gatacacatg gagctgtttg     1800

ggaattttcc ttgctgctac cgcgctgcca ccaaatggaa ttgaccagcg gctgttacac     1860

tgttctttgc cactgtgcct atgctcagaa tatgctcact gctaagctac aaactcggac     1920

agggtcagaa acagaggtgt cccatcccat tgcagcctcc accacctgta accccttcct     1980

ggcattggcc actgaagggt acaaaggcaa aaggaccaca gcaccactta ggtgtagcat     2040

ggattttaaa ctgcagtcag tatcagatcc tgtttgataa ataagctgac tgttctctct     2100

tgagaacctg tggcctcaac cagccaccaa gctgatgtgg cccaagtcca tctcttggtc     2160

ttctcctttg aagcacagcc tatttctgag ccaagggttg gggaagcctg tctagatgtg     2220

ggactcattg ccccaaacca gggagaggaa gagctcccac agggagagcc caggctctct     2280

ttgcagcctt tcccagtttg gtgtttaagc agtgccatgt tccttgtttg acaacaagac     2340

agtctgtaaa gtattgctct taaaaacaat taaaaagaac cctttcatat tggcaccatt     2400

gccttagtcc tctgtgggtt ggtcttcagc cagcattctg gtgggagtga ctggcattaa     2460

caagactgga aatcgggggt caaagtaaaa tatctttgtt ttgctttcat tcacaaagta     2520

atgaagccag ctgccaatta catcctccca acagcacttt ggtctgtgga ctgctgtgtg     2580

aatattcaga agggaagtaa gtattcaggg ggtaaacagg tctcccagca ttctgagtgt     2640

tccaaaccag taatccacat gccaattcaa atagaacagc cccttgctag atattaccac     2700

agataatgac agttacatgg tagaactgcc catgccacaa atatttattt ggaaaagtag     2760

tcattaaatg aacccactgc cttaaatgtc ttgaatgttg cagtcaagtg tctgtcatgt     2820

gttgatatcc acacagaatt aggccctaat gagagcctta gaccctcaac catgccccct     2880

tcgttggcat cacagggcct tatttggaag agcgggcaaa gaggatggaa atcataaaat     2940

atttcatggg aatcgaacct agggatagtg ctccacttct gacgatggag tgaagacact     3000

tggcagactt gagccagaca cttcacctag tagttcctga aactgtgagc accactgcac     3060

taagccagtg cggagctgtt agggacgggc ccagctcctg caccacggac acagaatgtc     3120

tggagagggc cagcaggccc tctgagggtt ctggaatctg tgcaccttat ttgaccacac     3180

tccaaaattc tgtttttatt ttaacccttg aatctgcttt atgtacataa tcaaaatatc     3240

tatatctata tctatatcta tatctatata tttttaatca tctacatgta aatgaagcaa     3300

tagaattcta acataaggcc aagaaatgag acgaatgttt ggggtttatg ttttttaagg     3360

taaatacggg tattgttttt aattattacc atgtattaaa ttgtgggctt tgaaacctaa     3420

tgaaacctgt tagccacttc tctgtgccat atacttccca tgttaccaaa atacccccaa     3480

ctctttagcc aaaagagaac cctgacctcc tgagtttcca tgctcctttc tgtaccaggt     3540

ttaaatgtag tcttctggag aagtattttt gacattgagc tctgggacag gacaccttgg     3600

gtttgtggac tgcagcccac tatgatgtta ttacttctct ggccaggcct ccagtggaag     3660

tgcacaggca ctcccaatgt tgttaatgct ctgtcttcca tttgttctgg aatcctacgt     3720

gttggtctgt ggttccatgc attagctgtt tgtaaataat gcatttgcat actgaaaaag     3780

gaatgccacc tgccacagtt gatggtgagg aagctccttt gacgtggtgc aattttgatg     3840

agatgtctct ggggacacga ggatgcccta atgatgctga cttgtcatgg ttgcagcatt     3900

tgaacttttg gtgttaaaaa aaaaaacctg taagtctgta acctggcaac attttacaac     3960

cctgtatttt taaagatggc tttctaataa aaaatccaga accacacagc cctatggtca     4020

aacaatccta cgtttgtgcc tctgctttta aaggtgctgt gctggacagt tggcatgcca     4080

gggttcgaga agagtgaatg gcttgacgta cttgcagtta actgtgcaaa attggctggc     4140

tgcctctgtt cctactgtac tgtaactttg atcatgtctg ttcctgttcc attctcccag     4200

gagcttctct gcagactgac acaccctccc ccaccccggg tagtggagat gctggtgtct     4260

gggtagtcat ggatttctgc tggacatttg aatgtgataa acaatccagc attacttagg     4320

aaatgctaca tgcggaatgt gcacgtttcc aggggcgagt attgtcaatc aaaaggtttg     4380

caatgatttc cttcctgcca aaaataaaca tgtgaaactg ca                        4422


<210>  514
<211>  1681
<212>  DNA
<213>  homo sapiens

<400>  514
ggggcgtgaa gggagccggg atcagccagg ggccagcatg agccggaggg agggaagtct       60

ggaagacccc cagactgatt cctcagtctc acttcttccc cacttggagg ccaagatccg      120

tcagacacac agccttgcgc acctcctcac caaatacgct gagcagctgc tccaggaata      180

tgtgcagctc cagggagacc ccttcgggct gcccagcttc tcgccgccgc ggctgccggt      240

ggccggcctg agcgccccgg ctccgagcca cgcggggctg ccagtgcacg agcggctgcg      300

gctggacgcg gcggcgctgg ccgcgctgcc cccgctgctg gacgcagtgt gtcgccgcca      360

ggccgagctg aacccgcgcg cgccgcgcct gctgcgccgc ctggaggacg cggcgcgcca      420

ggcccgggcc ctgggcgccg ccgtggaggc cttgctggcc gcgctgggcg ccgccaaccg      480

cgggccccgg gccgagcccc ccgccgccac cgcctcagcc gcctccgcca ccggggtctt      540

ccccgccaag gtgctggggc tccgcgtttg cggcctctac cgcgagtggc tgagccgcac      600

cgagggcgac ctgggccagc tgctgcccgg gggctcggcc tgagcgccgc ggggcagctc      660

gccccgcctc ctcccgctgg gttccgtctc tccttccgct tctttgtctt tctctgccgc      720

tgtcggtgtc tgtctgtctg ctcttagctg tctccattgc ctcggccttc tttgcttttt      780

gtgggggaga ggggagggga cgggcagggt ctctgtcgcc caggctgggg tgcagtggcg      840

cgatcccagc actgcagcct caacctcctg ggctcaagcc atccttccgc ctcagcttcc      900

ccagcagctg ggactacagg cacgcgccac cacagccggc taatttttta tttaattttt      960

tgtagagacg aggtttcgcc atgttgccca ggctggtctt gaactccggg gctcaagcga     1020

tcctcccgct tcagcctccc taagtgctgg gattgcaggc gtgagccact ttcccagcct     1080

ctctttgctt tgcctgcccc gttctcttaa ctcttggacc ctcctcgtct gcatggtaac     1140

tccgtctgag tctaccattt tcttgctctc cctccttcct tgggcctgcc tcagttccct     1200

ttggcctccc cctttaccca gctcttgggg tgtctctgtt ttttccatcc ccacttcctg     1260

ccttctcgtg gccctgtgtg agcacatgtg tacatctcag ccttatctca aggaggtgac     1320

accttctctc cttgtcccca tctggccgtc tctctgtgct tccctggcca ggggcgtgcc     1380

tgctggtcct atggggggaa ggctactctg catctcagcc accttcctca ggctcactcc     1440

acctacatcc ccagtctgcc acaccccatc cctttgggcc tcagccctgt ccctttgatg     1500

tcctcctttc cttcagcccc tctgccctgt ccctgcacac ctccactgcc tcccagcaga     1560

tctgtggaga caaaacaagc aacaccttaa aagagtttta tttctgaaaa taaattaatt     1620

ttttgtaaat aaaatgttta aaaataaaaa agaaactaaa gttaaaaaaa aaaaaaaaaa     1680

a                                                                     1681


<210>  515
<211>  3256
<212>  DNA
<213>  homo sapiens

<400>  515
aggatacagc ggcttctgcg cgacttataa gagctccttg tgcggcgcca ttttaagcct       60

ctcggtctgt ggcagcagcg ttggcccggc cccgggagcg gagagcgagg ggaggcggag      120

acggaggaag gtctgaggag cagcttcagt ccccgccgag ccgccaccgc aggtcgagga      180

cggtcggact cccgcggcgg gaggagcctg ttcccctgag ggtatttgaa gtataccata      240

caactgtttt gaaaatccag cgtggacaat ggctactcaa gctgatttga tggagttgga      300

catggccatg gaaccagaca gaaaagcggc tgttagtcac tggcagcaac agtcttacct      360

ggactctgga atccattctg gtgccactac cacagctcct tctctgagtg gtaaaggcaa      420

tcctgaggaa gaggatgtgg atacctccca agtcctgtat gagtgggaac agggattttc      480

tcagtccttc actcaagaac aagtagctga tattgatgga cagtatgcaa tgactcgagc      540

tcagagggta cgagctgcta tgttccctga gacattagat gagggcatgc agatcccatc      600

tacacagttt gatgctgctc atcccactaa tgtccagcgt ttggctgaac catcacagat      660

gctgaaacat gcagttgtaa acttgattaa ctatcaagat gatgcagaac ttgccacacg      720

tgcaatccct gaactgacaa aactgctaaa tgacgaggac caggtggtgg ttaataaggc      780

tgcagttatg gtccatcagc tttctaaaaa ggaagcttcc agacacgcta tcatgcgttc      840

tcctcagatg gtgtctgcta ttgtacgtac catgcagaat acaaatgatg tagaaacagc      900

tcgttgtacc gctgggacct tgcataacct ttcccatcat cgtgagggct tactggccat      960

ctttaagtct ggaggcattc ctgccctggt gaaaatgctt ggttcaccag tggattctgt     1020

gttgttttat gccattacaa ctctccacaa ccttttatta catcaagaag gagctaaaat     1080

ggcagtgcgt ttagctggtg ggctgcagaa aatggttgcc ttgctcaaca aaacaaatgt     1140

taaattcttg gctattacga cagactgcct tcaaatttta gcttatggca accaagaaag     1200

caagctcatc atactggcta gtggtggacc ccaagcttta gtaaatataa tgaggaccta     1260

tacttacgaa aaactactgt ggaccacaag cagagtgctg aaggtgctat ctgtctgctc     1320

tagtaataag ccggctattg tagaagctgg tggaatgcaa gctttaggac ttcacctgac     1380

agatccaagt caacgtcttg ttcagaactg tctttggact ctcaggaatc tttcagatgc     1440

tgcaactaaa caggaaggga tggaaggtct ccttgggact cttgttcagc ttctgggttc     1500

agatgatata aatgtggtca cctgtgcagc tggaattctt tctaacctca cttgcaataa     1560

ttataagaac aagatgatgg tctgccaagt gggtggtata gaggctcttg tgcgtactgt     1620

ccttcgggct ggtgacaggg aagacatcac tgagcctgcc atctgtgctc ttcgtcatct     1680

gaccagccga caccaagaag cagagatggc ccagaatgca gttcgccttc actatggact     1740

accagttgtg gttaagctct tacacccacc atcccactgg cctctgataa aggctactgt     1800

tggattgatt cgaaatcttg ccctttgtcc cgcaaatcat gcacctttgc gtgagcaggg     1860

tgccattcca cgactagttc agttgcttgt tcgtgcacat caggataccc agcgccgtac     1920

gtccatgggt gggacacagc agcaatttgt ggagggggtc cgcatggaag aaatagttga     1980

aggttgtacc ggagcccttc acatcctagc tcgggatgtt cacaaccgaa ttgttatcag     2040

aggactaaat accattccat tgtttgtgca gctgctttat tctcccattg aaaacatcca     2100

aagagtagct gcaggggtcc tctgtgaact tgctcaggac aaggaagctg cagaagctat     2160

tgaagctgag ggagccacag ctcctctgac agagttactt cactctagga atgaaggtgt     2220

ggcgacatat gcagctgctg ttttgttccg aatgtctgag gacaagccac aagattacaa     2280

gaaacggctt tcagttgagc tgaccagctc tctcttcaga acagagccaa tggcttggaa     2340

tgagactgct gatcttggac ttgatattgg tgcccaggga gaaccccttg gatatcgcca     2400

ggatgatcct agctatcgtt cttttcactc tggtggatat ggccaggatg ccttgggtat     2460

ggaccccatg atggaacatg agatgggtgg ccaccaccct ggtgctgact atccagttga     2520

tgggctgcca gatctggggc atgcccagga cctcatggat gggctgcctc caggtgacag     2580

caatcagctg gcctggtttg atactgacct gtaaatcatc ctttaggagt aacaatacaa     2640

atggattttg ggagtgactc aagaagtgaa gaatgcacaa gaatggatca caagatggaa     2700

tttatcaaac cctagccttg cttgttaaat tttttttttt ttttttttaa gaatatctgt     2760

aatggtactg actttgcttg ctttgaagta gctctttttt tttttttttt tttttttttg     2820

cagtaactgt tttttaagtc tctcgtagtg ttaagttata gtgaatactg ctacagcaat     2880

ttctaatttt taagaattga gtaatggtgt agaacactaa ttcataatca ctctaattaa     2940

ttgtaatctg aataaagtgt aacaattgtg tagccttttt gtataaaata gacaaataga     3000

aaatggtcca attagtttcc tttttaatat gcttaaaata agcaggtgga tctatttcat     3060

gtttttgatc aaaaactatt tgggatatgt atgggtaggg taaatcagta agaggtgtta     3120

tttggaacct tgttttggac agtttaccag ttgcctttta tcccaaagtt gttgtaacct     3180

gctgtgatac gatgcttcaa gagaaaatgc ggttataaaa aatggttcag aattaaactt     3240

ttaattcatt cgattg                                                     3256


<210>  516
<211>  8636
<212>  DNA
<213>  homo sapiens

<400>  516
gcttccggtt gctagcgccg gtcagagaga aagtcggcat gttctcgcag gctgccgggc       60

gtcccggggt tgcctcttgc ccgtgaccct gacgggagac agagcgcggg cggccgcggc      120

gtccctgtca gcgcccgcgg cgaggacccc ggggctgggg cggacggcgt gcccctgagg      180

ggggtccccg cgggagcgcg gagccggcga ctggtgcttc ccacgtgcgc cggtgtcgcg      240

agggcccggg aggacgcaga gcacggccgg gagaagcatg ggaaggaggc cgagccggga      300

tctcaggtcc tcgggggcgg cggccacgcc aaggacggta caaaactttt taccaacaaa      360

aaaaagcaag tagttatact caggaagaac ttcaagacac ttacgggttt cttctgtttg      420

atactgaaaa gcaggtgtat acatttccaa atactccgac tgtcttcatt caagaccatg      480

gtatcatggg aaatctggtt atgttgtaat ttttaatata attaagtatt acttttacga      540

actttcaggc aacaccgtta ttgaacgacc cagacagatc tgtccttatg taattgtagc      600

ttttcgatac agggaatcta aaactatggc accaccagct cataaaagca tacttgaacg      660

cagtgaaaat gttctcatgt ctccatggaa agggaaatta attgttcaag accgtatgct      720

atgtgatata gctctttggt ccacttacgg tgcaatgatt ccaacacagc taccgcagga      780

actagatttt aaatatgtaa tgaaagtgtc ttccttgaaa aaaagactac cagaggctgc      840

cttcagaaaa cagaattact tggaggagaa agtctgtttt caagatttgt gcttcaattt      900

gtatgaggta gaactgtcaa acagacaagg ggaaaatata gataaattaa cagaatgtat      960

taaaaacaag caattggcaa tcatcaaatg cttagaagat cgagggtttt tcattttact     1020

tacatcatca gccttactat cagaaccaga ttttggaggc aagcagatgg gtctgcatgg     1080

gttacattta tttcgttcac ccctgtcaac aggggtgaaa gatttgaaag ttgaagatga     1140

catctcaatg aaggtgatac ctattttatc tacccttaat tgtgccctgc tagaaacaaa     1200

gaaatcactt cctgaagaaa gaatccatcc aaacacatta gtaaagcgtc atttccaaga     1260

attgtacaag gcggacagaa gcccttcatt gagtgttgct cctcaggata gaatgaaaga     1320

ccctacattc ttggggaaac tgcccagtgg ttttgacttg attcctccag ctgaaaagtg     1380

cccttcagag tctttaactc agttgaactc ttatttttca gaccctagtg cttacatttt     1440

ggaagtgtct actgctttgg acttgctagc agagcatcct cagtctcctt gtgtttcaga     1500

cggaatttgt gatgctggat tttccttagt tatgactcca gatcctgaat ttcttgtctc     1560

agaggcagaa gtgagaaaag aaactgaaac aaaaaaggat tctgaagaaa tgttgaaagc     1620

aaagaagaga gtttttccat tgagtccagc gtcaaatctg agagtgcagc ctaagaggaa     1680

ggccagcatg ccccacatgg tgcagagtaa aaaggtgaac ttgtgccgcc cctttcccaa     1740

aagaactgct tccagagcag acaacagctc ggactctcca acaactctta agttagttaa     1800

aggacagttt cctcagaaaa gaaaaagagg tgcggaagtg ctgactgcac agtttgtaca     1860

gaaaaccaaa ttggatagga aaaaccaaga agctcctatt tctaaagatg ttccagtgcc     1920

aacaaatgct aaaagggcaa ggaaacaaga gaaatctcca gtcaaaactg ttccaagggc     1980

taagccacct gtgaagaaat ctccacaaaa acagagagta aatatagtaa aaggcaatga     2040

gaaccccaga aacagaaagc agctacaacc tgtcaaagga gaaactgctt caaagcttca     2100

atcagaaatt tcaagaggtt gtcaagaaga tgggattagc ataaatagtg ttcaaccaga     2160

aaataccaca gcggctcaca atgatcttcc tgaaaactcc atcgtcaact atgactccca     2220

ggccctaaat atgttagccg atctagcatt aagctctgct acttcttcca caccagtatc     2280

tgaggctaga aatcttcact gttcctctga attgccacaa aatgatgttt tgctctctaa     2340

agaaaattct ttgcgaggta catctgacca tgaatatcat agaggagtta aaactcaaaa     2400

aggtgaatta ctacctaacc catcttctga taggaagagt aattctggat cagacttaac     2460

agttagccaa gatgaagaaa gcttggttcc ttgtagtcag gcccctgcta aagcccagtc     2520

agcacttact gaggaaatgc tagaatcttc agatgcaagc caaagctctt ctgtttctgt     2580

ggaacattca tatgccctgc tccttacaga acattcaaag aaacatctac aggagagaga     2640

gatactaagc cctctgtttc ccaggaatgg gacaaaaagc cctgaagcag caaccccagt     2700

ggggaaagtc atgccatttc ggcatcagcc cggccttttg cttcagcaaa agcctcctga     2760

cgaccccgtg gtgaagccca aggatcgacc accgtctgcc cgtgtgaaaa aatcttcttg     2820

ctctcgtata gtgcttagct gtgatgactc cgttaagatc actttcaaat gtgaaacaga     2880

atatgcattc agtttagaca gcaaatatac caacaaccca ctggagaaaa ctgtagtaag     2940

agcattacat gggccctgga atactgattt gcctgataat gtggaagaag tgaagctttt     3000

acttcatatg tgggtagctc tgttttacag caatcagaac aaaatcatac gatcttcccg     3060

aaaggttgta gaacacagca acccagcaaa atatgtgtct ataaatagca cgttagaatc     3120

ttgtgagctc cgtgaaattg aggagtccct tggtttggaa aaatgttctg cagactctct     3180

gttggagact aacgaaattt ccagggctca tgctgctgaa gtatccttcc gtgatcctaa     3240

ctgcttgctt cctttcatta aaacaccact tacccaaggc ttggaactct gtgtacaaaa     3300

tgaacagaaa aaaacttttg caagagagtg tgatccagac acccaagaag accagaattt     3360

catctgttct tacaataatg aggtaactgg ggaagaagct aaacaagaat cattggagac     3420

ttctaatctt gtgctttcgg gtattggaag tacacaaact aatggacctt ctgttcctag     3480

tgaagaagaa attgttcagc cactggatag cacaagagtg gcttcttaca gtggcactgt     3540

tactcaagcc acattcacca ggacttacga tgggcctggc agtcagccag tgatatgtca     3600

gagctctgtg tacggcaccc ttgaaaacaa agtggatatt cttgatgcag cagtgcaaac     3660

aaaaacaggt actttacagg accttatcca acatggcagc cccataaaca atgaatgtca     3720

cccttccttg gaaagaaagg atgataatat ggggtgtgca gtgattaacc cggaaccaat     3780

tactctcacc tttgaaaaaa atgcacatgt accaatacag acagaaggtg taaatactgc     3840

tgatgaacgt acaaccttta agaaggagtt gattaagcaa gtatcacctg ctgcaagcct     3900

tagacatcct gtatccacct cggaaaatgc acgaacacaa ggcctgaggg acattccctc     3960

tctagtagtt gcaggacaga agggcactaa gtacctttgt gcctcgtcag taggtggaga     4020

gacacttgat aaagcagtgt gttcattaca gaaggagacg ccccttccag tctctctacc     4080

atctgataaa acaatggtca tggaggcact atcattagct aaaagttcta gtcatctatc     4140

acccagtgaa gaagtgagat gcactcagga tttcctttca cagactcaga gtctcctcgg     4200

cctatcttca gaagggcttc tagaactgac acaggttgaa gtggactcat catcagcctc     4260

taccaccttg ggaaggcagt gttcacttaa ctgcatttcg tcaggatgcc acacatcagg     4320

tgactcttta gaactaagga agaatcacaa gaatggtcca aacactgaaa atatgaattt     4380

ggaagcgttt gattcagtat ttatcaaaca aacaagcctg tctgtgagta gagaggtcag     4440

cctagagtta tcagaggaag attctgacat tgacttagct ctaacaatat caccacctac     4500

aagtcccaga gaagaaatgc cagctggtga aatagagcaa tttgaggagg ccccattctc     4560

aaatttagaa cttcaggatg tagctgagga aataggtgaa ccggaagagg tggctctcac     4620

agaaagcaga gaagtgagtt ctgctgacaa tgtgtcagta tatccctcag tgtcagaaga     4680

accagtagaa aataaggaga gaaaggggga taatttacaa ccagttactt taatactttc     4740

taaagaaaat tgcacccttg agattgcaga ggaaattaat gtgacctctg attttccctt     4800

tgattctgta attgaagaag tatcaccagc gtctagtcct gaacctccag taccagttaa     4860

agagacacga ccatatcagg ctgtgactcc atgcatttta aaacttcatg gtacacagtg     4920

tgagaagagc aaccaaatct cccaatgtga gtcagaagac ttaggcataa cagaaaaaga     4980

aaatgttttt gttggtccta cccatccagt ggggcaagat aactttaccc aggtacaaca     5040

aatgcaggtc tctgccgaaa tgcctctaat attaactgat catccaggaa gaacaggtag     5100

accaaccctt cctggtaaag taactgagga aattgtctca agtgagcatg atgagggttt     5160

atctttctca ggaaaggtgc agtgctatgg tagggagtta aaccagcctg cctcagctgc     5220

caaatgcaca ggtgacttca gtccttctcc tgaaaaactg gtaaaatcag gaaatccatt     5280

gcagccagtt agtatagaga atagaaattt ggacttaaaa catcttgtct tggagtccag     5340

tgaacctcca tttggtccta gaaatgttat tgaaaataag tctttgtctg acacattggt     5400

ttccacaact gcaccaagtg gtatagtgaa tgtgtcagta aaacagcaga ctagccctaa     5460

aagcagtcag aaccatctct ttcccggtga tttgaaaaca gatgaaggca tttatctgca     5520

ggtgaagtcc ttgacagctg cctcggttga tggagcttat tctacacagg gatgcatgtg     5580

ctcagtggtc cccacgcttt gttcttcctc agacaatgct acattaaccc attatgtaag     5640

accaataaat gcagagccag cgtttcaagc acaggaaata ccagcaggca gaatggccag     5700

tttgcttaag aatggtgagc ctgaagctga gttacataaa gaaaccacag gtccaggcac     5760

tgctggccct cagtccaaca ccacatcttc tctaaaaggt gaacgcaaag ccatccacac     5820

gctgcaagat gtgtcaacat gtgaaacaaa ggagctattg aatgtcgggg tttcctccct     5880

ttgtgctggt ccctaccaaa atacagcaga caccaaggaa aacctcagta aagagccttt     5940

ggcctccttt gtttcagaat cctttgatac ttctgtttgt ggaatagcca cagagcacgt     6000

agaaattgag aacagtgggg aggggctcag ggctgaggct ggttctgaaa ccctaggcag     6060

agatggagag gtcggtgtga attccgacat gcactatgaa ctctctggag attctgatct     6120

agacctgctt ggtgattgta gaaatcccag actggatttg gaggattctt atactttaag     6180

aggtagttac accaggaaaa aagatgttcc cacagatggc tatgagtcgt cgttgaactt     6240

ccacaacaac aaccaagagg actggggctg ctctagctgg gttccaggca tggagacgag     6300

cctccctccc gggcactgga ctgctgcggt aaagaaagaa gagaagtgtg tgccgcctta     6360

cgtccaaatc cgagatctcc acgggatcct caggacttac gccaacttct ctataacaaa     6420

agaactcaaa gataccatga gaacttcaca cggcctgagg aggcacccga gtttcagtgc     6480

aaactgtggc ctgcccagct cctggacaag cacttggcag gtggcagacg acctcaccca     6540

gaacacttta gacctggagt atctgcgttt tgcacataaa ctaaaacaga ccataaagaa     6600

tggggattct cagcattctg cctcctctgc caatgtcttt ccaaaggagt caccaaccca     6660

gatctccatt ggtgctttcc cttcgacaaa aatctctgag gccccatttc tgcatcctgc     6720

acctaggagc agaagccccc ttctggtaac agttgtggag tcagatccca gaccacaggg     6780

gcagcccagg agaggctaca cagccagcag tctggacagc tcttcctctt ggagagagag     6840

atgtagtcat aatagagatc ttagaaattc tcaaagaaat cacactgttt cattccacct     6900

caacaaactg aaatacaaca gtactgtgaa ggaatctcgg aatgatattt cacttattct     6960

caatgagtat gctgaattca acaaggtgat gaagaatagc aaccaattca ttttccaaga     7020

caaagagcta aatgatgttt ctggagaagc cactgctcaa gagatgtatc tgcctttccc     7080

aggacggtca gcctcctatg aagacataat catagacgtg tgcaccaatt tgcacgtcaa     7140

actaagaagt gttgtgaaag aggcttgtaa aagtaccttc ctgttctacc ttgtcgaaac     7200

agaagacaaa tcattctttg taagaacaaa gaaccttctg aggaaaggag gccatacaga     7260

aattgaacct cagcacttct gtcaagcttt ccacagagag aatgatacac taatcatcat     7320

catcagaaat gaagatatat catcacattt gcatcagatt ccttctttgc tgaagctgaa     7380

gcatttcccc agtgtcatct ttgctggagt agacagccct ggagatgttc ttgatcacac     7440

ctaccaagaa ctgtttcgtg caggaggctt tgtgatatca gatgacaaga tactagaagc     7500

tgtaacatta gttcaactga aggaaattat caaaatcctg gaaaaactaa atggaaatgg     7560

aagatggaag tggttgcttc actacaggga aaataaaaag ctaaaagaag atgaaagagt     7620

ggattcaact gcacataaga agaacataat gttgaagtca tttcagagtg caaatatcat     7680

tgaattgctt cattatcacc agtgtgactc tcgatcatca acaaaagcag aaattctgaa     7740

atgtttgcta aacctgcaaa ttcagcatat tgatgccagg tttgctgtcc tcctaacaga     7800

caagcctact atccccagag aagtctttga aaatagtgga atccttgtta cagatgtaaa     7860

taactttata gaaaacatag aaaaaatagc agctccattt aggagtagct attggtgact     7920

caactacagc ctgcctggat atggatgatg ccaataaaaa attagtattt tccctttgga     7980

aaacttgtga acatgtgaat acacatgtga acagtcttac atttgaaaaa ccaatgttct     8040

acaacttgga aagttttcat tttttatatt ttgctgaaat atgtcacagt ggcattgcag     8100

ttgtctgtta gctttgggtt gcagtgctag atattgtttt aaattatttt cattttaaac     8160

aagatgcctt ctaagctatt gagcttatta aaaataattt tacatgttta cttagttgga     8220

gcaaaaataa gtctatttta acaaatagct ttgtttttgc atgctaatgt cagaaaggca     8280

tacgatgcac attatgctct gttttaaagg ttttaccacc cttgtaaaaa ctataatctt     8340

aaatggtttt atttgctgtt acacaaacaa cactacataa aacatttttt cctaaatggt     8400

acaaatttat aaactatcat ttttcactta cggtatttgt aaatactaca ctacaaaaat     8460

cagctttctg agaaagaaat aatcatttat ttatgatatt gaaaatttct acagtaaaca     8520

ctcaaaacca agcaaaaaac atttgtaaga tacacggtat ctatttggag caacggtttt     8580

tgtaactaat gtgtttcatt ttttaaataa agacaactaa aaataaaaaa aaaaaa         8636


<210>  517
<211>  8636
<212>  DNA
<213>  homo sapiens

<400>  517
gcttccggtt gctagcgccg gtcagagaga aagtcggcat gttctcgcag gctgccgggc       60

gtcccggggt tgcctcttgc ccgtgaccct gacgggagac agagcgcggg cggccgcggc      120

gtccctgtca gcgcccgcgg cgaggacccc ggggctgggg cggacggcgt gcccctgagg      180

ggggtccccg cgggagcgcg gagccggcga ctggtgcttc ccacgtgcgc cggtgtcgcg      240

agggcccggg aggacgcaga gcacggccgg gagaagcatg ggaaggaggc cgagccggga      300

tctcaggtcc tcgggggcgg cggccacgcc aaggacggta caaaactttt taccaacaaa      360

aaaaagcaag tagttatact caggaagaac ttcaagacac ttacgggttt cttctgtttg      420

atactgaaaa gcaggtgtat acatttccaa atactccgac tgtcttcatt caagaccatg      480

gtatcatggg aaatctggtt atgttgtaat ttttaatata attaagtatt acttttacga      540

actttcaggc aacaccgtta ttgaacgacc cagacagatc tgtccttatg taattgtagc      600

ttttcgatac agggaatcta aaactatggc accaccagct cataaaagca tacttgaacg      660

cagtgaaaat gttctcatgt ctccatggaa agggaaatta attgttcaag accgtatgct      720

atgtgatata gctctttggt ccacttacgg tgcaatgatt ccaacacagc taccgcagga      780

actagatttt aaatatgtaa tgaaagtgtc ttccttgaaa aaaagactac cagaggctgc      840

cttcagaaaa cagaattact tggaggagaa agtctgtttt caagatttgt gcttcaattt      900

gtatgaggta gaactgtcaa acagacaagg ggaaaatata gataaattaa cagaatgtat      960

taaaaacaag caattggcaa tcatcaaatg cttagaagat cgagggtttt tcattttact     1020

tacatcatca gccttactat cagaaccaga ttttggaggc aagcagatgg gtctgcatgg     1080

gttacattta tttcgttcac ccctgtcaac aggggtgaaa gatttgaaag ttgaagatga     1140

catctcaatg aaggtgatac ctattttatc tacccttaat tgtgccctgc tagaaacaaa     1200

gaaatcactt cctgaagaaa gaatccatcc aaacacatta gtaaagcgtc atttccaaga     1260

attgtacaag gcggacagaa gcccttcatt gagtgttgct cctcaggata gaatgaaaga     1320

ccctacattc ttggggaaac tgcccagtgg ttttgacttg attcctccag ctgaaaagtg     1380

cccttcagag tctttaactc agttgaactc ttatttttca gaccctagtg cttacatttt     1440

ggaagtgtct actgctttgg acttgctagc agagcatcct cagtctcctt gtgtttcaga     1500

cggaatttgt gatgctggat tttccttagt tatgactcca gatcctgaat ttcttgtctc     1560

agaggcagaa gtgagaaaag aaactgaaac aaaaaaggat tctgaagaaa tgttgaaagc     1620

aaagaagaga gtttttccat tgagtccagc gtcaaatctg agagtgcagc ctaagaggaa     1680

ggccagcatg ccccacatgg tgcagagtaa aaaggtgaac ttgtgccgcc cctttcccaa     1740

aagaactgct tccagagcag acaacagctc ggactctcca acaactctta agttagttaa     1800

aggacagttt cctcagaaaa gaaaaagagg tgcggaagtg ctgactgcac agtttgtaca     1860

gaaaaccaaa ttggatagga aaaaccaaga agctcctatt tctaaagatg ttccagtgcc     1920

aacaaatgct aaaagggcaa ggaaacaaga gaaatctcca gtcaaaactg ttccaagggc     1980

taagccacct gtgaagaaat ctccacaaaa acagagagta aatatagtaa aaggcaatga     2040

gaaccccaga aacagaaagc agctacaacc tgtcaaagga gaaactgctt caaagcttca     2100

atcagaaatt tcaagaggtt gtcaagaaga tgggattagc ataaatagtg ttcaaccaga     2160

aaataccaca gcggctcaca atgatcttcc tgaaaactcc atcgtcaact atgactccca     2220

ggccctaaat atgttagccg atctagcatt aagctctgct acttcttcca caccagtatc     2280

tgaggctaga aatcttcact gttcctctga attgccacaa aatgatgttt tgctctctaa     2340

agaaaattct ttgcgaggta catctgacca tgaatatcat agaggagtta aaactcaaaa     2400

aggtgaatta ctacctaacc catcttctga taggaagagt aattctggat cagacttaac     2460

agttagccaa gatgaagaaa gcttggttcc ttgtagtcag gcccctgcta aagcccagtc     2520

agcacttact gaggaaatgc tagaatcttc agatgcaagc caaagctctt ctgtttctgt     2580

ggaacattca tatgccctgc tccttacaga acattcaaag aaacatctac aggagagaga     2640

gatactaagc cctctgtttc ccaggaatgg gacaaaaagc cctgaagcag caaccccagt     2700

ggggaaagtc atgccatttc ggcatcagcc cggccttttg cttcagcaaa agcctcctga     2760

cgaccccgtg gtgaagccca aggatcgacc accgtctgcc cgtgtgaaaa aatcttcttg     2820

ctctcgtata gtgcttagct gtgatgactc cgttaagatc actttcaaat gtgaaacaga     2880

atatgcattc agtttagaca gcaaatatac caacaaccca ctggagaaaa ctgtagtaag     2940

agcattacat gggccctgga atactgattt gcctgataat gtggaagaag tgaagctttt     3000

acttcatatg tgggtagctc tgttttacag caatcagaac aaaatcatac gatcttcccg     3060

aaaggttgta gaacacagca acccagcaaa atatgtgtct ataaatagca cgttagaatc     3120

ttgtgagctc cgtgaaattg aggagtccct tggtttggaa aaatgttctg cagactctct     3180

gttggagact aacgaaattt ccagggctca tgctgctgaa gtatccttcc gtgatcctaa     3240

ctgcttgctt cctttcatta aaacaccact tacccaaggc ttggaactct gtgtacaaaa     3300

tgaacagaaa aaaacttttg caagagagtg tgatccagac acccaagaag accagaattt     3360

catctgttct tacaataatg aggtaactgg ggaagaagct aaacaagaat cattggagac     3420

ttctaatctt gtgctttcgg gtattggaag tacacaaact aatggacctt ctgttcctag     3480

tgaagaagaa attgttcagc cactggatag cacaagagtg gcttcttaca gtggcactgt     3540

tactcaagcc acattcacca ggacttacga tgggcctggc agtcagccag tgatatgtca     3600

gagctctgtg tacggcaccc ttgaaaacaa agtggatatt cttgatgcag cagtgcaaac     3660

aaaaacaggt actttacagg accttatcca acatggcagc cccataaaca atgaatgtca     3720

cccttccttg gaaagaaagg atgataatat ggggtgtgca gtgattaacc cggaaccaat     3780

tactctcacc tttgaaaaaa atgcacatgt accaatacag acagaaggtg taaatactgc     3840

tgatgaacgt acaaccttta agaaggagtt gattaagcaa gtatcacctg ctgcaagcct     3900

tagacatcct gtatccacct cggaaaatgc acgaacacaa ggcctgaggg acattccctc     3960

tctagtagtt gcaggacaga agggcactaa gtacctttgt gcctcgtcag taggtggaga     4020

gacacttgat aaagcagtgt gttcattaca gaaggagacg ccccttccag tctctctacc     4080

atctgataaa acaatggtca tggaggcact atcattagct aaaagttcta gtcatctatc     4140

acccagtgaa gaagtgagat gcactcagga tttcctttca cagactcaga gtctcctcgg     4200

cctatcttca gaagggcttc tagaactgac acaggttgaa gtggactcat catcagcctc     4260

taccaccttg ggaaggcagt gttcacttaa ctgcatttcg tcaggatgcc acacatcagg     4320

tgactcttta gaactaagga agaatcacaa gaatggtcca aacactgaaa atatgaattt     4380

ggaagcgttt gattcagtat ttatcaaaca aacaagcctg tctgtgagta gagaggtcag     4440

cctagagtta tcagaggaag attctgacat tgacttagct ctaacaatat caccacctac     4500

aagtcccaga gaagaaatgc cagctggtga aatagagcaa tttgaggagg ccccattctc     4560

aaatttagaa cttcaggatg tagctgagga aataggtgaa ccggaagagg tggctctcac     4620

agaaagcaga gaagtgagtt ctgctgacaa tgtgtcagta tatccctcag tgtcagaaga     4680

accagtagaa aataaggaga gaaaggggga taatttacaa ccagttactt taatactttc     4740

taaagaaaat tgcacccttg agattgcaga ggaaattaat gtgacctctg attttccctt     4800

tgattctgta attgaagaag tatcaccagc gtctagtcct gaacctccag taccagttaa     4860

agagacacga ccatatcagg ctgtgactcc atgcatttta aaacttcatg gtacacagtg     4920

tgagaagagc aaccaaatct cccaatgtga gtcagaagac ttaggcataa cagaaaaaga     4980

aaatgttttt gttggtccta cccatccagt ggggcaagat aactttaccc aggtacaaca     5040

aatgcaggtc tctgccgaaa tgcctctaat attaactgat catccaggaa gaacaggtag     5100

accaaccctt cctggtaaag taactgagga aattgtctca agtgagcatg atgagggttt     5160

atctttctca ggaaaggtgc agtgctatgg tagggagtta aaccagcctg cctcagctgc     5220

caaatgcaca ggtgacttca gtccttctcc tgaaaaactg gtaaaatcag gaaatccatt     5280

gcagccagtt agtatagaga atagaaattt ggacttaaaa catcttgtct tggagtccag     5340

tgaacctcca tttggtccta gaaatgttat tgaaaataag tctttgtctg acacattggt     5400

ttccacaact gcaccaagtg gtatagtgaa tgtgtcagta aaacagcaga ctagccctaa     5460

aagcagtcag aaccatctct ttcccggtga tttgaaaaca gatgaaggca tttatctgca     5520

ggtgaagtcc ttgacagctg cctcggttga tggagcttat tctacacagg gatgcatgtg     5580

ctcagtggtc cccacgcttt gttcttcctc agacaatgct acattaaccc attatgtaag     5640

accaataaat gcagagccag cgtttcaagc acaggaaata ccagcaggca gaatggccag     5700

tttgcttaag aatggtgagc ctgaagctga gttacataaa gaaaccacag gtccaggcac     5760

tgctggccct cagtccaaca ccacatcttc tctaaaaggt gaacgcaaag ccatccacac     5820

gctgcaagat gtgtcaacat gtgaaacaaa ggagctattg aatgtcgggg tttcctccct     5880

ttgtgctggt ccctaccaaa atacagcaga caccaaggaa aacctcagta aagagccttt     5940

ggcctccttt gtttcagaat cctttgatac ttctgtttgt ggaatagcca cagagcacgt     6000

agaaattgag aacagtgggg aggggctcag ggctgaggct ggttctgaaa ccctaggcag     6060

agatggagag gtcggtgtga attccgacat gcactatgaa ctctctggag attctgatct     6120

agacctgctt ggtgattgta gaaatcccag actggatttg gaggattctt atactttaag     6180

aggtagttac accaggaaaa aagatgttcc cacagatggc tatgagtcgt cgttgaactt     6240

ccacaacaac aaccaagagg actggggctg ctctagctgg gttccaggca tggagacgag     6300

cctccctccc gggcactgga ctgctgcggt aaagaaagaa gagaagtgtg tgccgcctta     6360

cgtccaaatc cgagatctcc acgggatcct caggacttac gccaacttct ctataacaaa     6420

agaactcaaa gataccatga gaacttcaca cggcctgagg aggcacccga gtttcagtgc     6480

aaactgtggc ctgcccagct cctggacaag cacttggcag gtggcagacg acctcaccca     6540

gaacacttta gacctggagt atctgcgttt tgcacataaa ctaaaacaga ccataaagaa     6600

tggggattct cagcattctg cctcctctgc caatgtcttt ccaaaggagt caccaaccca     6660

gatctccatt ggtgctttcc cttcgacaaa aatctctgag gccccatttc tgcatcctgc     6720

acctaggagc agaagccccc ttctggtaac agttgtggag tcagatccca gaccacaggg     6780

gcagcccagg agaggctaca cagccagcag tctggacagc tcttcctctt ggagagagag     6840

atgtagtcat aatagagatc ttagaaattc tcaaagaaat cacactgttt cattccacct     6900

caacaaactg aaatacaaca gtactgtgaa ggaatctcgg aatgatattt cacttattct     6960

caatgagtat gctgaattca acaaggtgat gaagaatagc aaccaattca ttttccaaga     7020

caaagagcta aatgatgttt ctggagaagc cactgctcaa gagatgtatc tgcctttccc     7080

aggacggtca gcctcctatg aagacataat catagacgtg tgcaccaatt tgcacgtcaa     7140

actaagaagt gttgtgaaag aggcttgtaa aagtaccttc ctgttctacc ttgtcgaaac     7200

agaagacaaa tcattctttg taagaacaaa gaaccttctg aggaaaggag gccatacaga     7260

aattgaacct cagcacttct gtcaagcttt ccacagagag aatgatacac taatcatcat     7320

catcagaaat gaagatatat catcacattt gcatcagatt ccttctttgc tgaagctgaa     7380

gcatttcccc agtgtcatct ttgctggagt agacagccct ggagatgttc ttgatcacac     7440

ctaccaagaa ctgtttcgtg caggaggctt tgtgatatca gatgacaaga tactagaagc     7500

tgtaacatta gttcaactga aggaaattat caaaatcctg gaaaaactaa atggaaatgg     7560

aagatggaag tggttgcttc actacaggga aaataaaaag ctaaaagaag atgaaagagt     7620

ggattcaact gcacataaga agaacataat gttgaagtca tttcagagtg caaatatcat     7680

tgaattgctt cattatcacc agtgtgactc tcgatcatca acaaaagcag aaattctgaa     7740

atgtttgcta aacctgcaaa ttcagcatat tgatgccagg tttgctgtcc tcctaacaga     7800

caagcctact atccccagag aagtctttga aaatagtgga atccttgtta cagatgtaaa     7860

taactttata gaaaacatag aaaaaatagc agctccattt aggagtagct attggtgact     7920

caactacagc ctgcctggat atggatgatg ccaataaaaa attagtattt tccctttgga     7980

aaacttgtga acatgtgaat acacatgtga acagtcttac atttgaaaaa ccaatgttct     8040

acaacttgga aagttttcat tttttatatt ttgctgaaat atgtcacagt ggcattgcag     8100

ttgtctgtta gctttgggtt gcagtgctag atattgtttt aaattatttt cattttaaac     8160

aagatgcctt ctaagctatt gagcttatta aaaataattt tacatgttta cttagttgga     8220

gcaaaaataa gtctatttta acaaatagct ttgtttttgc atgctaatgt cagaaaggca     8280

tacgatgcac attatgctct gttttaaagg ttttaccacc cttgtaaaaa ctataatctt     8340

aaatggtttt atttgctgtt acacaaacaa cactacataa aacatttttt cctaaatggt     8400

acaaatttat aaactatcat ttttcactta cggtatttgt aaatactaca ctacaaaaat     8460

cagctttctg agaaagaaat aatcatttat ttatgatatt gaaaatttct acagtaaaca     8520

ctcaaaacca agcaaaaaac atttgtaaga tacacggtat ctatttggag caacggtttt     8580

tgtaactaat gtgtttcatt ttttaaataa agacaactaa aaataaaaaa aaaaaa         8636


<210>  518
<211>  1235
<212>  DNA
<213>  homo sapiens

<400>  518
ctctttcccg gagcctgggc ggagagggag gaaaacttct tcctggcctg ggctccgtgc       60

cgctctgttt gccaaccgtc cagtcccgcc taccagtgcc gggcgctccc cacccctccc      120

ccggctcccc cggtgtccgc catggccaaa gcctacgacc acctcttcaa gttgctgctg      180

atcggggact cgggggtggg caagacttgt ctgatcattc gctttgcaga ggacaacttc      240

aacaacactt acatctccac catcggaatt gatttcaaga tccgcactgt ggatatagag      300

gggaagaaga tcaaactaca agtctgggac acggctggcc aagagcggtt caagacaata      360

actactgcct actaccgtgg agccatgggc attatcctag tatacgacat cacggatgag      420

aaatctttcg agaatattca gaactggatg aaaagcatca aggagaatgc ctcggctggg      480

gtggagcgcc tcttgctggg gaacaaatgt gacatggagg ccaagaggaa ggtgcagaag      540

gagcaggccg ataagttggc tcgagagcat ggaatccgat ttttcgaaac tagtgctaaa      600

tccagtatga atgtggatga ggcttttagt tccctggccc gggacatctt gctcaagtca      660

ggaggccgga gatcaggaaa cggcaacaag cctcccagta ctgacctgaa aacttgtgac      720

aagaagaaca ccaacaagtg ctccctgggc tgaggaccct ttcttgcctc cccaccccgg      780

aagctgaacc tgagggagac aacggcagag ggagtgagca ggggagaaat agcagagggg      840

cttggagggt cacataggta gatggtaaag agaatgagga gaaaaaggag aaaagggaaa      900

agcagaaagg aaaaaaagga agagagagga agggagaagg gagaggaatg aattgaggaa      960

gtgaaagaag gcaaggaggt aggaagagag ggaggaggaa aggaaggaga gatgcctcag     1020

gcttcagacc ttacctgggt tttcagggca aacataaatg taaatacact gatttattct     1080

gttactagat caggttttag ggtcctgcaa aaggctagct cggcactaca ctagggaatt     1140

tgctcctgtt ctgtcacttg tcatggtctt tcttggtatt aaaggccacc atttgcacaa     1200

atgttcctgt tttgggtaac ttggattatt gtcag                                1235


<210>  519
<211>  3523
<212>  DNA
<213>  homo sapiens

<400>  519
ttcctggtcc agaactttac acagaaaagg tgctcaaagg atatttgttt aatgaatgtg       60

gtatgctgac atttaaacag gacaaaactt gtagaacttc atggaggaac acggagtgac      120

ccaaaccgaa catatggcta ccatagaagc acatgcagtg gcccagcaag tgcagcaggt      180

ccatgtggct acttacaccg agcatagtat gctgagtgct gatgaagact cgccttcttc      240

tcccgaggac acctcttacg atgactcaga tatactcaac tccacagcag ctgatgaggt      300

gacagctcat ctggcagctg caggtcctgt gggaatggcc gctgctgctg ctgtggcaac      360

aggaaagaaa cggaaacggc ctcatgtatt tgagtctaat ccatctatcc ggaagaggca      420

acaaacacgt ttgcttcgga aacttcgagc cacgttagat gaatatacta ctcgtgtggg      480

acagcaagct attgtcctct gtatctcacc ctccaaacct aaccctgtct ttaaagtgtt      540

tggtgcagca cctttggaga atgtggtgcg taagtacaag agcatgatcc tggaagacct      600

ggagtctgct ctggcagaac acgcccctgc gccacaggag gttaactcag aactgccgcc      660

tctcaccatc gacggaattc cagtctctgt ggacaaaatg acccaggccc agcttcgggc      720

atttatccca gagatgctca agtactctac aggtcgggga aaaccaggct gggggaaaga      780

aagctgcaag cccatctggt ggcctgaaga tatcccctgg gcaaatgtcc ggagtgatgt      840

ccgcacagaa gagcaaaagc agagggtttc atggacccag gcactacgga ccatagttaa      900

aaactgttat aaacagcatg ggcgggaaga ccttttgtat gcctttgaag atcagcaaac      960

gcaaacacag gccacagcca cacatagtat agctcatctt gtaccatcac agactgtagt     1020

ccagactttt agtaaccctg atggcactgt ctcacttatc caggttggta cgggggcaac     1080

agtagccaca ttggctgatg cttcagaatt gccaaccacg gtcaccgttg cccaagtgaa     1140

ttattctgcc gtggctgatg gagaggtgga acaaaattgg gccacgttac agggaggtga     1200

gatgaccatc cagacgacgc aagcatcaga ggccacccag gcggtggcat cgttggcaga     1260

ggccgcagtg gcagcttctc aggagatgca gcagggagct acagtcacta tggcgcttaa     1320

cagcgaagct gccgcccatg ctgtcgccac cctggctgag gccaccttac aaggtggggg     1380

acagatcgtc ttgtctgggg aaaccgcagc agccgtcgga gcacttactg gagtccaaga     1440

tgctaatggc ctggtccaga tccctgtgag catgtaccag actgtggtga ccagcctcgc     1500

ccagggcaac ggaccagtgc aggtggccat ggcccctgtg accaccagga tatcagacag     1560

cgcagtcacc atggacggcc aagctgtgga ggtggtgaca ttggaacagt gacatacagc     1620

catattatgg catcgttttc tagtctactt caaaattttt tacacgtttg cagaggtgca     1680

atcaaatgga attaagtctc tcgactttgg aaggaaagtt ttgttaacct tttttttttt     1740

aaaaggaaga aagcggattt tggaattgca ttttttaaag caccactctt gattttctgg     1800

gattggtgaa gaaactgcat tgtcaatttc actgtcccaa aaaagccaaa ttgtggcagg     1860

acttctttct gcggaaatgt gtgtgtatac ttatgtgtgt gtatgtgtga gtgtgaatat     1920

atgtatatgt gtacatatgg acatacacat ttacatatat ataaagtata tatatacata     1980

tatatatata tatatgtatg aaacccgcat ggaattatct gtatgaaatc aaggtgcgct     2040

gtggaaacaa taattcaccc agtttagtgg gtggtagggt acgtggccag acacagtcac     2100

ccagtttttg ttcataccag ggtcatgcgt tgagctactg acaaactcag gcggaggtga     2160

ccatgccctt caccaaagct gcctcccagt ggccacacag aactctccct gctggactca     2220

cctgaggaaa gaggctccag catggggtgg gtcagagatg tgcttgcaag gtccagggac     2280

tgcgtggtct gccagctgag atgctcctcg ggctggccca ggtgctgacc ttgccacagg     2340

cagatgaatg tcttgaaagc tcccgggcct cagcctccca tctcctctcc ttcccaggaa     2400

tccttgatct catgactatt aaaatgttgc tctggtttta aggtcagtcc tgaattgctc     2460

gtatatatga actgaaggta accgaagtat taggggtttg aggagtgcgt gcgtgtaagt     2520

gtgcttgtgt gtgtgcgtgc atggtggggg agaggatggg aagggggcgg gggcagtgga     2580

agggaaagga aggaaagaaa aatcgtccta gaccaggata cacccgtggg agcaattttc     2640

tctactgtct gtagcttcac agaggaggcg ctggaatgaa caagaagaga catctggtct     2700

gtggccacag caccctgaac gcccctgatc ttgtgtgatc ttggaagcta agcttggttg     2760

ggcccggtca gtacgcggaa gggaagaagg gacacctggc catagaaaac agctgagggt     2820

gtttgctgtg ttcctggatc aggccctgct tcagaaggga ctcctggagg cccatgttcc     2880

ttgatgcaac ctcgtggccc aggccgggag cagcttgcct cctcagaggt gttgactatc     2940

tgggtgttct tggtaaccgt taactctgtc tttctcagct gcaagccctg agtctccagt     3000

agctgaattc acctgacttt tcaacaggcc aaatctctga accttgagta cagggacagc     3060

tcctcctccc tcctcccagc tctccccatg tgtgtgatgg tgtatttaat gtgttttttt     3120

aatgcgacat taaaagattc tccacgtctt gctcaacctt tgagagaagt ttcagattct     3180

tgtatttgct tgttttatat aaaactatct aatgttcttt atatgttctt ttctgtacgt     3240

aatgggggga ggggagggaa atttacatat aaatagtcct agttctacaa tttgttattt     3300

ttttaattat tattttttat cgtcattgtg aagttgtcca gggactttaa agtccatgtt     3360

cctttgtggt gaaataacct ccaaatagtt tgagaagttg ccaagacgaa gaaaaaagca     3420

aaaccccagt agcagagcat ggattctgtg ttgtttccca ttctgtcttt gactgcctca     3480

ttcaataaat agttaaaaat gtggcaacag gaaaaaaaaa aaa                       3523


<210>  520
<211>  6168
<212>  DNA
<213>  homo sapiens

<400>  520
ggtcgcgccc gctggggccc gcgatggcgg gggcctggct caggtggggg ctcctgctct       60

gggcagggct cctcgcgtcc tcggcgcacg gccggctgcg gaggatcacc tacgtggtgc      120

acccgggccc cggcctggca gccggcgcct tgcccctgag cgggcccccg cgttcgcgga      180

cattcaacgt cgcgctcaac gccaggtaca gccgcagctc ggcggctgcc ggcgccccca      240

gccgtgcctc ccccggggtc ccctcggaga ggacccggcg cacgagcaag ccgggcggcg      300

cggccctgca ggggctcaga ccgccgccgc cgccgccgcc ggagcctgcg cgtcccgcgg      360

tccccggcgg gcagctccac cccaatcccg gcggccaccc ggcagccgcc ccgttcacca      420

aacaaggcag gcaagttgtg cgctccaagg tgccgcagga gacccagagc ggcggaggct      480

ctaggctgca ggttcaccag aagcagcagc tgcagggggt caatgtctgt ggagggcggt      540

gctgtcatgg ctggagtaag gcccctggct cccagaggtg caccaaacct agctgtgttc      600

cgccatgtca gaatggaggg atgtgtctcc ggccacaact ctgtgtgtgt aaaccaggga      660

ccaagggcaa agcctgtgaa acaatagctg cccaggacac ctcgtcacca gtctttggag      720

ggcagagtcc tggggctgct tcctcgtggg gccctcctga gcaagcagca aagcatactt      780

catctaagaa ggcagacact ctaccaagag tcagccctgt ggcccagatg accttaaccc      840

tcaagccgaa gccttcagtg ggactccccc agcagataca ttctcaagtg actcctcttt      900

cttcccagag tgtggtgatt caccatggcc agacccagga atacgtgctc aagcccaagt      960

actttccagc ccagaagggg atttcaggag agcagtccac tgaaggttct ttccctttaa     1020

gatatgtgca ggatcaagtt gcggcacctt ttcagctgag taaccacact ggccgcatca     1080

aggtggtctt tactccgagc atctgtaaag tgacctgcac caagggcagc tgtcagaaca     1140

gctgtgagaa ggggaacacc accactctca ttagtgagaa tggtcatgct gccgacaccc     1200

tgacggccac gaacttccga gtggtaattt gccatcttcc atgtatgaat ggtggccagt     1260

gcagttcaag ggacaaatgt cagtgccctc caaatttcac aggaaaactt tgtcagatcc     1320

cagtccatgg tgccagcgtg cctaaacttt atcagcattc ccagcagcca ggcaaggcgt     1380

tggggacgca tgtcatccat tcaacacata ccttgcctct gaccgtgact agccagcaag     1440

gagtcaaagt gaaatttcct cctaacatag tcaatatcca tgtgaaacat cctcctgaag     1500

cttccgtcca gatacatcag gtttcaagaa ttgatggccc aacaggccag aagacaaaag     1560

aagctcaacc aggccaatcc caagtctcgt accaagggct tcctgtccag aagacccaga     1620

ccatacattc cacatactcc caccagcagg tcattcctca cgtctacccc gtggctgcta     1680

agacacagct tggccggtgc ttccaggaaa ccattgggtc acagtgtggc aaagcgctcc     1740

ctggcctttc aaagcaagag gactgctgtg gaactgtggg tacctcctgg ggctttaaca     1800

aatgccagaa atgccccaag aaaccatctt atcatggata caaccaaatg atggaatgcc     1860

taccgggtta taagcgggtt aacaacacct tttgccaaga tattaatgaa tgtcagctac     1920

aaggtgtatg ccctaatggt gagtgtttga ataccatggg cagctatcga tgtacctgca     1980

aaataggatt tgggccggat cctacctttt caagttgtgt tcctgatccc cctgtgatct     2040

cggaagagaa agggccctgt taccgacttg tcagttctgg aagacagtgt atgcaccctc     2100

tgtctgttca cctcaccaag cagctctgct gttgtagtgt gggcaaggcc tggggcccac     2160

actgtgagaa atgtcccctt ccaggcacag ctgcttttaa ggaaatctgt cctggtggaa     2220

tgggttatac ggtttctggc gttcatagac gcaggccaat ccatcaccat gtaggtaaag     2280

gacctgtatt tgtcaagcca aagaacactc aacctgttgc taaaagtact catcctccac     2340

ctctcccagc caaggaagag ccagtggagg ccctgacctt ctcccgggaa cacgggccag     2400

gagtggcgga gccagaagtg gcaactgcac cccctgaaaa ggaaatacct tcattggatc     2460

aagagaaaac caaacttgag cctggtcaac cccagctgtc tccaggcatt tccactattc     2520

atctgcatcc acagtttcca gtagtgattg aaaaaacatc acctcctgtg cctgttgaag     2580

tagctcctga agcttctacg tctagtgcca gccaagtgat tgctcctact caagtgacag     2640

aaatcaatga atgtactgtg aaccctgata tctgtggagc aggacactgc attaacctac     2700

cagtgagata tacctgtata tgctacgagg gctacaggtt cagtgaacaa cagaggaaat     2760

gtgtggatat tgatgagtgt actcaggtcc aacacctctg ctcccagggc cgctgtgaaa     2820

acaccgaggg aagtttcttg tgcatttgcc cagcaggatt tatggccagt gaggagggta     2880

ctaactgcat agatgttgac gaatgcctga ggccggacgt ctgtggggag gggcactgtg     2940

tcaatactgt gggggccttc cggtgtgaat actgtgacag cgggtaccgc atgactcaga     3000

gaggccgttg tgaggatatt gatgaatgtt tgaatccaag cacttgtcca gatgagcagt     3060

gtgtgaattc tcctggatct taccagtgcg ttccctgcac agaaggattc cgaggctgga     3120

atggacagtg ccttgatgtg gacgagtgcc tggaaccaaa cgtctgcgca aatggtgatt     3180

gttccaacct tgaaggctcc tacatgtgtt catgccacaa aggctatacc cggactccgg     3240

accacaagca ctgtagagat attgatgaat gtcagcaagg gaatctatgt gtaaacgggc     3300

agtgcaaaaa taccgagggc tccttcaggt gcacctgtgg acaggggtac cagctgtcgg     3360

cagctaaaga ccagtgtgaa gacattgatg aatgccagca ccgtcatctc tgtgctcatg     3420

ggcagtgcag gaacactgag ggctcttttc aatgtgtgtg tgaccagggt tacagagcat     3480

ctgggcttgg agaccactgt gaagatatca atgaatgctt ggaggacaag agtgtttgcc     3540

agagaggaga ctgcattaat actgcagggt cctatgattg tacttgtccg gatggatttc     3600

agctagatga caataaaaca tgtcaagata ttaatgaatg tgaacatcca gggctctgtg     3660

gtccgcaagg ggagtgccta aacacagagg gttctttcca ttgtgtctgc cagcagggtt     3720

tctcaatctc tgcagatggc cgtacgtgtg aagatattga tgaatgtgta aacaacactg     3780

tttgtgacag tcacgggttt tgtgacaata cagctggctc cttccgctgc ctctgttatc     3840

agggctttca agccccacag gatgggcaag ggtgtgtgga tgtgaatgaa tgtgaactgc     3900

tcagtggggt gtgtggtgaa gccttctgtg aaaacgtgga agggtccttc ctgtgcgtgt     3960

gtgctgatga aaaccaagag tacagcccca tgactgggca gtgccgctcc cggacctcca     4020

cagatttaga tgtagatgta gatcaaccca aagaagaaaa gaaagaatgc tactataatc     4080

tcaatgacgc cagtctctgt gataatgtgt tggcccccaa tgtcacgaaa caagaatgct     4140

gctgtacatc aggcgcggga tggggagata actgcgaaat cttcccctgc ccggtcttgg     4200

gaactgctga gttcactgaa atgtgtccca aagggaaagg ttttgtgcct gctggagaat     4260

catcttctga agctggtggt gagaactata aagatgcaga tgaatgccta ctttttggac     4320

aagaaatctg caaaaatggt ttctgtttga acactcggcc tgggtatgaa tgctactgta     4380

agcaagggac gtactatgat cctgtgaaac tgcagtgctt tgatatggat gaatgtcaag     4440

accccagtag ttgtattgat ggccagtgtg ttaatacaga gggctcttac aactgcttct     4500

gtactcaccc catggtcctg gatgcgtcag aaaaaagatg tatacgaccg gctgagtcaa     4560

acgaacaaat agaagaaact gatgtctacc aagatttgtg ctgggaacat ctgagtgatg     4620

aatacgtgtg tagccggcct cttgtgggca agcagacaac gtacactgag tgctgctgtc     4680

tgtatggaga ggcctggggc atgcagtgtg ccctctgccc cctgaaggat tcagatgact     4740

atgctcagct gtgtaacatc cccgtgacgg gacgccggca gccatatgga cgggacgcct     4800

tggttgactt cagtgaacag tatactccag aagccgatcc ctacttcatc caagaccgtt     4860

ttctaaatag ctttgaggag ttacaggctg aggaatgcgg catcctcaat ggatgtgaaa     4920

atggtcgctg tgtgagggtc caggaaggtt acacctgcga ttgctttgat gggtatcact     4980

tggatacggc caagatgacc tgtgtcgatg taaatgaatg cgatgagttg aacaaccgga     5040

tgtctctctg caagaatgcc aagtgcatta acaccgatgg ttcctacaag tgtttgtgtc     5100

tgccaggcta cgtgccttct gacaagccaa actactgcac tccgttgaat accgccttga     5160

atttagagaa agacagtgac ctggagtgaa acagaatcta cataacctaa gcccatatac     5220

tctgcactgt gtaaaggaaa agggagaaat gtattatact tgagacattg cacctacccc     5280

ggaaggctgg aaatacagaa acagcatgga attgcaagtc ctctgaagac aatgagagga     5340

tttaggatga gcccgatagg tgtggcagac caaatggaca tttctctaaa aaaccagtat     5400

atatagtctg ttcatatgta aaattcaatg gaagagaggt ggaacagtgc tgttatttta     5460

aacagaaggt tgtattatta tgttgttttg tttttttact attgcttgat taaatttggc     5520

atttaaatag tggtggaaat attttatata attttcattt tttggttgtg cagttccttg     5580

gctactgttt ttcttttact tcagtttttt aaaaatctca aatgaaaaag tcttcgatac     5640

aatattgtta agctgtatta taagtattgt tacacagggt tatgcaattc ccggcctgga     5700

gcatttttga aattcaaatt gtctgtcctg tggagcaggc agtgattttg ttccaaaact     5760

ttgtatacac atttggagaa aagtacttta tattttcagt gttttgtctg attttaatgt     5820

ccgttcttag ccaagctgct agcaggtgtt aattggatcc ctttccttca ctgaaatgga     5880

agagtttata agcttacgtt agtattgtaa tatgtaaagt aagcccaaca aaaattttta     5940

aaaatttgat gatccccaat atatctacca ttgtatgtta aataaatcac catttttgta     6000

gaaaaaattc tacctgagag taattgtcaa tgagtacatg tgtataagtt gtatcccact     6060

ctccccactt ttatcttttc cagtggtctt ctgttaatgt agtgtctttt acaagttaat     6120

cattaaattt gttagatctt gttatgggct aaaaaaaaaa aaaaaaaa                  6168


<210>  521
<211>  1310
<212>  DNA
<213>  homo sapiens

<400>  521
gacccggaag cagagccaca gcgcgtcgcg gcagccccca aggaagacca gcctgcctct       60

ggtcggttcc tggcgctctg cgtttcgtga ccttgtccag tagaaggcta tttaattttc      120

acaactgctt gaattttgac atacaagatg aagcaagatg cctcaagaaa tgctgcctac      180

actgtggatt gtgaagatta tgtgcatgtg gtagaattta atccctttga gaatggggat      240

tcaggaaacc taattgcata tggtggcaat aattatgtgg tcattggcac gtgtacgttt      300

caggaagaag aagcagacgt tgaaggcatt cagtataaaa cacttcgaac atttcaccat      360

ggagtcaggg ttgatggcat agcttggagc ccagagacta gacttgattc attgcctcca      420

gtaatcaaat tttgtacttc agctgctgat atgaaaatta gattatttac ttcagatctt      480

caggataaaa atgaatataa ggttttagag ggccataccg atttcattaa tggtttggtg      540

tttgatccca aagaaggcca agaaattgca agtgtgagtg acgatcacac ctgcaggatt      600

tggaacttgg aaggagtgca aacagctcat tttgttcttc attctcctgg catgagtgtg      660

tgctggcatc ctgaggagac ttttaagcta atggttgcag agaagaatgg aacaatccgg      720

ttttatgatc ttttggccca acaggctatt ttatctcttg aatcagaaca agtgccatta      780

atgtcagcac actggtgctt aaaaaacacc ttcaaagttg gagccgttgc aggaaatgat      840

tggttaattt gggatattac tcggtccagt tatcctcaaa ataagagacc tgttcacatg      900

gatcgagcct gcttattcag gtggtccaca attagtgaaa atctgtttgc aaccactggt      960

tatcctggca aaatggcaag ccagtttcaa attcatcatt taggacaccc tcagcccatc     1020

ctcatgggtt ctgtagccgt tggatctgga ctgtcctggc atcgaactct ccctctgtgt     1080

gtaattggag gagaccacaa gctgttgttt tgggtgactg aagtataaag tgttttctgt     1140

accttagatt cacaaacttt gtatttttag tacatatttt gaagaatttc tatagtacat     1200

attttgaaga atttttatat caaatatacc gtatacttta gaaaatgtct cagttgcttt     1260

tattaaataa aatgttgatg gtttgaaaaa ttaaaaaaaa aaaaaaaaaa                1310


<210>  522
<211>  1310
<212>  DNA
<213>  homo sapiens

<400>  522
gacccggaag cagagccaca gcgcgtcgcg gcagccccca aggaagacca gcctgcctct       60

ggtcggttcc tggcgctctg cgtttcgtga ccttgtccag tagaaggcta tttaattttc      120

acaactgctt gaattttgac atacaagatg aagcaagatg cctcaagaaa tgctgcctac      180

actgtggatt gtgaagatta tgtgcatgtg gtagaattta atccctttga gaatggggat      240

tcaggaaacc taattgcata tggtggcaat aattatgtgg tcattggcac gtgtacgttt      300

caggaagaag aagcagacgt tgaaggcatt cagtataaaa cacttcgaac atttcaccat      360

ggagtcaggg ttgatggcat agcttggagc ccagagacta gacttgattc attgcctcca      420

gtaatcaaat tttgtacttc agctgctgat atgaaaatta gattatttac ttcagatctt      480

caggataaaa atgaatataa ggttttagag ggccataccg atttcattaa tggtttggtg      540

tttgatccca aagaaggcca agaaattgca agtgtgagtg acgatcacac ctgcaggatt      600

tggaacttgg aaggagtgca aacagctcat tttgttcttc attctcctgg catgagtgtg      660

tgctggcatc ctgaggagac ttttaagcta atggttgcag agaagaatgg aacaatccgg      720

ttttatgatc ttttggccca acaggctatt ttatctcttg aatcagaaca agtgccatta      780

atgtcagcac actggtgctt aaaaaacacc ttcaaagttg gagccgttgc aggaaatgat      840

tggttaattt gggatattac tcggtccagt tatcctcaaa ataagagacc tgttcacatg      900

gatcgagcct gcttattcag gtggtccaca attagtgaaa atctgtttgc aaccactggt      960

tatcctggca aaatggcaag ccagtttcaa attcatcatt taggacaccc tcagcccatc     1020

ctcatgggtt ctgtagccgt tggatctgga ctgtcctggc atcgaactct ccctctgtgt     1080

gtaattggag gagaccacaa gctgttgttt tgggtgactg aagtataaag tgttttctgt     1140

accttagatt cacaaacttt gtatttttag tacatatttt gaagaatttc tatagtacat     1200

attttgaaga atttttatat caaatatacc gtatacttta gaaaatgtct cagttgcttt     1260

tattaaataa aatgttgatg gtttgaaaaa ttaaaaaaaa aaaaaaaaaa                1310


<210>  523
<211>  7253
<212>  DNA
<213>  homo sapiens

<400>  523
agccgctgcg cccgagctgg cctgcgagtt cagggctcct gtcgctctcc aggagcaacc       60

tctactccgg acgcacaggc attccccgcg cccctccagc cctcgccgcc ctcgccaccg      120

ctcccggccg ccgcgctccg gtacacacag gatccctgct gggcaccaac agctccacca      180

tggggctggc ctggggacta ggcgtcctgt tcctgatgca tgtgtgtggc accaaccgca      240

ttccagagtc tggcggagac aacagcgtgt ttgacatctt tgaactcacc ggggccgccc      300

gcaaggggtc tgggcgccga ctggtgaagg gccccgaccc ttccagccca gctttccgca      360

tcgaggatgc caacctgatc ccccctgtgc ctgatgacaa gttccaagac ctggtggatg      420

ctgtgcgggc agaaaagggt ttcctccttc tggcatccct gaggcagatg aagaagaccc      480

ggggcacgct gctggccctg gagcggaaag accactctgg ccaggtcttc agcgtggtgt      540

ccaatggcaa ggcgggcacc ctggacctca gcctgaccgt ccaaggaaag cagcacgtgg      600

tgtctgtgga agaagctctc ctggcaaccg gccagtggaa gagcatcacc ctgtttgtgc      660

aggaagacag ggcccagctg tacatcgact gtgaaaagat ggagaatgct gagttggacg      720

tccccatcca aagcgtcttc accagagacc tggccagcat cgccagactc cgcatcgcaa      780

aggggggcgt caatgacaat ttccaggggg tgctgcagaa tgtgaggttt gtctttggaa      840

ccacaccaga agacatcctc aggaacaaag gctgctccag ctctaccagt gtcctcctca      900

cccttgacaa caacgtggtg aatggttcca gccctgccat ccgcactaac tacattggcc      960

acaagacaaa ggacttgcaa gccatctgcg gcatctcctg tgatgagctg tccagcatgg     1020

tcctggaact caggggcctg cgcaccattg tgaccacgct gcaggacagc atccgcaaag     1080

tgactgaaga gaacaaagag ttggccaatg agctgaggcg gcctccccta tgctatcaca     1140

acggagttca gtacagaaat aacgaggaat ggactgttga tagctgcact gagtgtcact     1200

gtcagaactc agttaccatc tgcaaaaagg tgtcctgccc catcatgccc tgctccaatg     1260

ccacagttcc tgatggagaa tgctgtcctc gctgttggcc cagcgactct gcggacgatg     1320

gctggtctcc atggtccgag tggacctcct gttctacgag ctgtggcaat ggaattcagc     1380

agcgcggccg ctcctgcgat agcctcaaca accgatgtga gggctcctcg gtccagacac     1440

ggacctgcca cattcaggag tgtgacaaga gatttaaaca ggatggtggc tggagccact     1500

ggtccccgtg gtcatcttgt tctgtgacat gtggtgatgg tgtgatcaca aggatccggc     1560

tctgcaactc tcccagcccc cagatgaacg ggaaaccctg tgaaggcgaa gcgcgggaga     1620

ccaaagcctg caagaaagac gcctgcccca tcaatggagg ctggggtcct tggtcaccat     1680

gggacatctg ttctgtcacc tgtggaggag gggtacagaa acgtagtcgt ctctgcaaca     1740

accccacacc ccagtttgga ggcaaggact gcgttggtga tgtaacagaa aaccagatct     1800

gcaacaagca ggactgtcca attgatggat gcctgtccaa tccctgcttt gccggcgtga     1860

agtgtactag ctaccctgat ggcagctgga aatgtggtgc ttgtccccct ggttacagtg     1920

gaaatggcat ccagtgcaca gatgttgatg agtgcaaaga agtgcctgat gcctgcttca     1980

accacaatgg agagcaccgg tgtgagaaca cggaccccgg ctacaactgc ctgccctgcc     2040

ccccacgctt caccggctca cagcccttcg gccagggtgt cgaacatgcc acggccaaca     2100

aacaggtgtg caagccccgt aacccctgca cggatgggac ccacgactgc aacaagaacg     2160

ccaagtgcaa ctacctgggc cactatagcg accccatgta ccgctgcgag tgcaagcctg     2220

gctacgctgg caatggcatc atctgcgggg aggacacaga cctggatggc tggcccaatg     2280

agaacctggt gtgcgtggcc aatgcgactt accactgcaa aaaggataat tgccccaacc     2340

ttcccaactc agggcaggaa gactatgaca aggatggaat tggtgatgcc tgtgatgatg     2400

acgatgacaa tgataaaatt ccagatgaca gggacaactg tccattccat tacaacccag     2460

ctcagtatga ctatgacaga gatgatgtgg gagaccgctg tgacaactgt ccctacaacc     2520

acaacccaga tcaggcagac acagacaaca atggggaagg agacgcctgt gctgcagaca     2580

ttgatggaga cggtatcctc aatgaacggg acaactgcca gtacgtctac aatgtggacc     2640

agagagacac tgatatggat ggggttggag atcagtgtga caattgcccc ttggaacaca     2700

atccggatca gctggactct gactcagacc gcattggaga tacctgtgac aacaatcagg     2760

atattgatga agatggccac cagaacaatc tggacaactg tccctatgtg cccaatgcca     2820

accaggctga ccatgacaaa gatggcaagg gagatgcctg tgaccacgat gatgacaacg     2880

atggcattcc tgatgacaag gacaactgca gactcgtgcc caatcccgac cagaaggact     2940

ctgacggcga tggtcgaggt gatgcctgca aagatgattt tgaccatgac agtgtgccag     3000

acatcgatga catctgtcct gagaatgttg acatcagtga gaccgatttc cgccgattcc     3060

agatgattcc tctggacccc aaagggacat cccaaaatga ccctaactgg gttgtacgcc     3120

atcagggtaa agaactcgtc cagactgtca actgtgatcc tggactcgct gtaggttatg     3180

atgagtttaa tgctgtggac ttcagtggca ccttcttcat caacaccgaa agggacgatg     3240

actatgctgg atttgtcttt ggctaccagt ccagcagccg cttttatgtt gtgatgtgga     3300

agcaagtcac ccagtcctac tgggacacca accccacgag ggctcaggga tactcgggcc     3360

tttctgtgaa agttgtaaac tccaccacag ggcctggcga gcacctgcgg aacgccctgt     3420

ggcacacagg aaacacccct ggccaggtgc gcaccctgtg gcatgaccct cgtcacatag     3480

gctggaaaga tttcaccgcc tacagatggc gtctcagcca caggccaaag acgggtttca     3540

ttagagtggt gatgtatgaa gggaagaaaa tcatggctga ctcaggaccc atctatgata     3600

aaacctatgc tggtggtaga ctagggttgt ttgtcttctc tcaagaaatg gtgttcttct     3660

ctgacctgaa atacgaatgt agagatccct aatcatcaaa ttgttgattg aaagactgat     3720

cataaaccaa tgctggtatt gcaccttctg gaactatggg cttgagaaaa cccccaggat     3780

cacttctcct tggcttcctt cttttctgtg cttgcatcag tgtggactcc tagaacgtgc     3840

gacctgcctc aagaaaatgc agttttcaaa aacagactca gcattcagcc tccaatgaat     3900

aagacatctt ccaagcatat aaacaattgc tttggtttcc ttttgaaaaa gcatctactt     3960

gcttcagttg ggaaggtgcc cattccactc tgcctttgtc acagagcagg gtgctattgt     4020

gaggccatct ctgagcagtg gactcaaaag cattttcagg catgtcagag aagggaggac     4080

tcactagaat tagcaaacaa aaccaccctg acatcctcct tcaggaacac ggggagcaga     4140

ggccaaagca ctaaggggag ggcgcatacc cgagacgatt gtatgaagaa aatatggagg     4200

aactgttaca tgttcggtac taagtcattt tcaggggatt gaaagactat tgctggattt     4260

catgatgctg actggcgtta gctgattaac ccatgtaaat aggcacttaa atagaagcag     4320

gaaagggaga caaagactgg cttctggact tcctccctga tccccaccct tactcatcac     4380

ctgcagtggc cagaattagg gaatcagaat caaaccagtg taaggcagtg ctggctgcca     4440

ttgcctggtc acattgaaat tggtggcttc attctagatg tagcttgtgc agatgtagca     4500

ggaaaatagg aaaacctacc atctcagtga gcaccagctg cctcccaaag gaggggcagc     4560

cgtgcttata tttttatggt tacaatggca caaaattatt atcaacctaa ctaaaacatt     4620

ccttttctct tttttcctga attatcatgg agttttctaa ttctctcttt tggaatgtag     4680

atttttttta aatgctttac gatgtaaaat atttattttt tacttattct ggaagatctg     4740

gctgaaggat tattcatgga acaggaagaa gcgtaaagac tatccatgtc atctttgttg     4800

agagtcttcg tgactgtaag attgtaaata cagattattt attaactctg ttctgcctgg     4860

aaatttaggc ttcatacgga aagtgtttga gagcaagtag ttgacattta tcagcaaatc     4920

tcttgcaaga acagcacaag gaaaatcagt ctaataagct gctctgcccc ttgtgctcag     4980

agtggatgtt atgggattct ttttttctct gttttatctt ttcaagtgga attagttggt     5040

tatccatttg caaatgtttt aaattgcaaa gaaagccatg aggtcttcaa tactgtttta     5100

ccccatccct tgtgcatatt tccagggaga aggaaagcat atacactttt ttctttcatt     5160

tttccaaaag agaaaaaaat gacaaaaggt gaaacttaca tacaaatatt acctcatttg     5220

ttgtgtgact gagtaaagaa tttttggatc aagcggaaag agtttaagtg tctaacaaac     5280

ttaaagctac tgtagtacct aaaaagtcag tgttgtacat agcataaaaa ctctgcagag     5340

aagtattccc aataaggaaa tagcattgaa atgttaaata caatttctga aagttatgtt     5400

ttttttctat catctggtat accattgctt tatttttata aattattttc tcattgccat     5460

tggaatagat atctcagatt gtgtagatat gctatttaaa taatttatca ggaaatactg     5520

cctgtagagt tagtatttct atttttatat aatgtttgca cactgaattg aagaattgtt     5580

ggttttttct tttttttgtt ttgttttttt tttttttttt ttttgctttt gacctcccat     5640

ttttactatt tgccaatacc tttttctagg aatgtgcttt tttttgtaca catttttatc     5700

cattttacat tctaaagcag tgtaagttgt atattactgt ttcttatgta caaggaacaa     5760

caataaatca tatggaaatt tatatttata cttactgtat ccatgcttat ttgttctcta     5820

ctggctttat gtcatgaagt atatgcgtaa ataccattca taaatcaata tagcatatac     5880

aaaaataaat tacagtaagt catagcaaca ttcacagttt gtatgtgatt gagaaagact     5940

gagttgctca ggcctaggct tagaatttgc tgcgtttgtg gaataaaaga acaaaatgat     6000

acattagcct gccatatcaa aaacatataa aagagaaatt atccctaagt caagggcccc     6060

cataagaata aaatttctta ttaaggtcat tagatgtcat tgaatccttt tcaaagtgca     6120

gtatgaaaac aaagggaaaa acactgaagc acacgcaact ctcacagcga cattttctga     6180

cccacgaatg atgccttggg tgggcaacac gattgcatgt tgtggagaca cttcggaagt     6240

aaatgtggat gagggaggag ctgtccttgc aatgttgagc caagcattac agatacctcc     6300

tcttgaagaa ggaataataa gtttaatcaa aaaagaagac taaaaaatgt aaaatttgga     6360

aggaatccat aaatgcgtgt gtgtctaaat acaaattatc atgtgaagaa aaggcccaag     6420

tgtaccaata agcagacctt gatttttgga tgggctaatt atgaatgtgg aatactgacc     6480

agttaatttc cagttttaat gaaaacagat caaagaagaa attttatgag taggttaaag     6540

gtctggcttt gaggtctatt aaacactaga aaggactggc tgggtgagat aaaatcttcc     6600

ttgttgattt tcactctcat tctataaata ctcatctttc tgagtagcca tgatcacata     6660

caaatgtaaa ttgccaaatc attttatagt accaaggtga agaagcagga actagaaagt     6720

gttgataata gctgtggagt taggaaaact gatgtgaagg aaataattct ttgaaatggc     6780

aaagaattaa ataccatcat tcattatcag aagagttcaa cgtttgaagt gctgggagat     6840

aattctaatt cattcttgga tagtgaagca aaactgattg aaaataccaa gataagacag     6900

aaaaagtgac tggaaagagg agcttttctt ccaggcatgt tccagtttca ccctaagact     6960

gaccttcaaa taatcaggtt gtactgaaat aaaggacttg ttaaaaatta aaattatgtc     7020

atcgagatga tagctttttt cctcctccaa cagtttattg tcatgtgttg tgggagagct     7080

cgagtgaaga gcaataaact ccaggtctta taagaatgta catacaataa aggtggtgcc     7140

agcagttttt ttttttctaa agagtcacat gtagaaaagc ctccagtatt aagctcctga     7200

attcattcct taaataaatt ggctctctct ctcttctata aaaaaaaaaa aaa            7253


<210>  524
<211>  9336
<212>  DNA
<213>  homo sapiens

<400>  524
gcggccgcgg gagctgcggg gagcgcgggg gcggcccgga gcgtgccggg gtccccgcgc       60

ctcgctcgcc ggccgcgctc cgaagatggt ggcggcgccg tgcgcccgga ggctggcccg      120

gcgctcgcac tcggcgctgc tcgcggcgct cacggtgctg ctgctgcaga cgctggtcgt      180

gtggaatttc agcagcctcg actccggggc cggggagcgc cgcgggggcg cagcggtcgg      240

cggcggggag cagccgcccc cggccccggc cccgcgccgg gagcgccggg acctgcccgc      300

cgagccggct gcagcccgag gaggaggagg aggcggcggc ggaggaggag gaggacgggg      360

gccccaggcg cgggcgcggg gaggcggccc cggagaaccg cggggacagc agccggccag      420

ccggggggca ctgcccgccc gggctctgga tccacaccca agtccgctca tcaccctgga      480

gactcaggat ggctactttt ctcatcggcc gaaagagaaa gtgcgaacag acagcaacaa      540

cgagaactct gtccccaaag actttgagaa tgtcgacaac agcaacttcg cacccaggac      600

tcaaaagcag aagcaccagc ctgagttggc gaagaagcca ccgagtagac agaaggagct      660

tttgaaaagg aagctggaac agcaggagaa aggaaaagga catacattcc ctgggaaagg      720

ccccggtgag gtgctgcctc ccggggacag agccgcagcc aacagcagcc acgggaagga      780

tgtgtccaga ccgcctcatg ccaggaaaac tgggggcagc tcccccgaga ccaagtatga      840

ccagccccct aagtgtgaca tctcaggcaa ggaggccatc tctgccctgt cccgtgctaa      900

gtccaagcac tgccgccagg agattgggga gacttactgc cgccacaagt tagggctgct      960

gatgcctgag aaggtgactc ggttctgccc cctcgagggt aaagccaaca agaacgtgca     1020

gtgggacgag gactccgtgg agtacatgcc agccaacccg gtcagaatcg cctttgtcct     1080

ggtggtccac ggccgtgcct ctcggcagtt gcagcgcatg ttcaaggcca tctaccacaa     1140

agaccacttc tactacatcc acgtggacaa gcgctctaat tacctgcatc ggcaagtgct     1200

ccaggtctcc aggcagtaca gcaatgtccg cgtcaccccc tggagaatgg ccaccatctg     1260

gggaggagcc agcctcctgt ccacctacct gcagagcatg cgggacctcc tggagatgac     1320

cgactggccc tgggacttct tcatcaacct gagtgcggcc gactacccca tcaggacaaa     1380

tgaccagttg gtggcgtttc tctcccgata ccgagatatg aatttcttga agtcacacgg     1440

ccgggacaat gcaaggttca ttcggaagca gggcctggat cggctcttcc tggagtgcga     1500

cgctcacatg tggcgcctgg gagatcggcg gatcccagag ggcattgccg tggatggcgg     1560

ttcggactgg ttcctgctga accggaggtt tgtagaatat gtgaccttct ccacagacga     1620

tctggtgacc aagatgaaac agttctactc ctacaccctg cttcctgctg agtccttctt     1680

ccatacggtc ctggagaaca gcccccactg cgacaccatg gtggacaaca acctgcgcat     1740

caccaactgg aatcgcaagc tgggctgcaa gtgccagtac aagcacatcg tggactggtg     1800

cggctgctcc cccaatgact tcaagccgca ggacttccac cgcttccagc agacagcccg     1860

gcctaccttc tttgcccgca agtttgaagc cgtggtgaat caggaaatca ttgggcagct     1920

ggactattac ctgtacggga actaccctgc aggtaccccg ggcctgcgct cctactggga     1980

gaatgtctac gatgagcctg acggcatcca cagcctgagc gacgtgacac tcaccttgta     2040

ccactccttt gcccgcctgg gtcttcgacg ggccgagacg tccctgcaca cggatgggga     2100

gaacagctgc cgatactacc caatgggcca cccagcatct gtgcacctct acttccttgc     2160

tgaccgcttc cagggctttc tgatcaagca tcatgctacc aatctggctg tgagcaaact     2220

agagactctg gagacctggg tgatgccgaa aaaagtcttc aagatcgcaa gcccacccag     2280

tgactttggg aggcttcagt tttccgaggt cggcactgac tgggatgcca aggagaggct     2340

attccgcaac tttgggggtc ttctggggcc catggatgag ccggtgggta tgcagaagtg     2400

ggggaaggga cctaatgtga ccgtgaccgt catttgggtg gatcccgtca atgtcatcgc     2460

agccacctac gacatcctca ttgagtccac tgccgaattc acacactaca agcccccttt     2520

gaacttgccc ctgaggcctg gggtctggac agtgaaaatt ctccaccact gggtgccagt     2580

tgcagagacc aaattcctcg ttgcgcctct gaccttctcg aacaggcagc ccatcaaacc     2640

tgaggaggca ctgaagctgc acaatgggcc cctccgcaat gcctacatgg agcagagctt     2700

ccagagccta aaccccgtcc tcagcctgcc catcaacccc gcccaggtgg aacaggcacg     2760

gaggaacgca gcctccacgg gcacagcgct ggagggatgg ctggactcgt tggtgggcgg     2820

gatgtggact gccatggaca tctgtgccac gggccccaca gcctgcccgg tcatgcagac     2880

ctgcagccag acggcctgga gctccttcag ccctgacccc aagtcggagc tgggggcagt     2940

caaacctgat ggccggctca ggtagcactg ggcacgagga gtgggccaca gcaggatctc     3000

aacgggaaag cagccagagg ggttgtgggg cctgaacccc ggcctcccac cctgggggag     3060

gccctctgtg aatgggtctc tcctggccat agaatgatgg aaagggaagg tcagcaggtc     3120

aaagcaggat cagccaacaa cctgcctttg gcaagctgcg ggtgggatgg ctcagtccct     3180

gcactgtgac tgtctcacct cttctggttg atcctcaagt cctacaggtt ccttgtcttc     3240

cccttccagt gacccacccc tgaccccaga cgtgtgattt tcagactttt ctttcgagca     3300

gcagaacttc gtttacggag cacagtcata agtggaggtt cagggtgctg acgaaatcca     3360

agctgctctg gttgaagctg acaagtgcga ggttccctcc caaagctcag ccctctgggc     3420

ggtccccttg cccagggtat ctcctacggt acctcttcag aacccaaggg ctctgcaaat     3480

gccagtttga caagcactgc ccagaccaac catgggttca aactccagcc ctgccctttg     3540

gttcattttt ctgcttctct tggctggggg actctggtgc cagccttgaa agtcatggtc     3600

gtgggccctt tcccatggag gctgcagcct taggagagct ctgagcctct cagcagccct     3660

ccttgggttg aactattctc cttagtaact aggtaagtgg gaaagccttt tgatgtggca     3720

tggccaaggt ccagccacaa gtgcaactgc cacctgtcca ggggtctggg cctccttccc     3780

tcaaggctgc cacacaaagt agcagaaata ggatgatgtt tgtgagcacc agactcaaga     3840

ccatgacctt ctttgatcct tgaaaatggg aactttgaca gccatgacca tgaaactcac     3900

aaggcaacgc gatgaaactc acaaagcaat gcttggagca aaactcctga gctagacagc     3960

acagcagcac ccatcccctg ccagagccct tccgttctga ggtcagacac acaaaacctt     4020

cgtcaattgc acaccggtgc tgttgggagt gaccaaacca catgaaccag acttttcccg     4080

tccaggaaat agcatttcag atttggtttt taatttcatg cccttcggcc acaggctcaa     4140

cgggacatgc aacataaaaa tgggaaggtt atttaaacaa caaaaaacag tatgatttaa     4200

gtgttgagtt accagaaacc caaaaggttt ccttgccacg agccccctgg agtgtcatcc     4260

ctgttcacca ggagagctct tcgcaggagg cctcccttgc tcctgtaatc ccacctcccc     4320

tgaatgatgg gattcccttg gaaaaaggtc tcacccctgg tagccatctg cccttcccat     4380

ggagagccag tcctgacact tctctccagc gtgggtttga aggggctgcc cttcgctttg     4440

tgtgacttgt cctaatccta gccagatgtg ttgccccatc ccaagcctcg caaggcaggg     4500

tgtcctgttg gcaatggagg acgtagagaa gggacacttt agatatttat tatttacatg     4560

ttttagtcga tgactaatta gtaggtgctg tttttgcagc ttgtcaatta tgttacctta     4620

ctaactgaag ctgcctttat tcacaaaagg ccccttttcc catcttttcc caccccctgg     4680

tgtctctctc tctctcggtt tctctttctc tgcgtctacc ccccatcctc ctcatcctca     4740

gagtaaagca ggggcatcga acaccacgca aagaaagctc caacccgcat cttccactgg     4800

ctttgagtgg ggtgccttgg ggaccgttgg agccttgttt ttttccttat gcagagtgtc     4860

agcctcactc tccctcggat tccaagagta ttggaattcc tgagcctccc atcctccccc     4920

tactcacccc ccgtcacagg cacaaggagg tgacaggcag aaaacgtgga gggtgagtgg     4980

ggaatgtgct agctgcagag agtttgtggg gaatgtgcta gctgcagaga gtttgggcca     5040

ttcctgcttg ctccgtggtt gccttcccat ggcccatcta attatgggca ttcatgcgac     5100

cttaacagag ggaaacaggc tcctttgaga gagatccatc ttaggaggag ggtcgtcaga     5160

tccaggcagc agagtccggg agatagccat tctcaacagc gattccaggg atctcagggt     5220

acttttctca gaaagcccct atgatctctt ttacagactc tatggtggcc acgcgctggg     5280

tgccacatcc tctttctgcc cccggcctct gcctctggcc agggtttccc tggggctgcc     5340

gaagccactt tgggagcttc cctttcaccc tccttgctgg gccaccagtg ctttgtgttc     5400

gcagcgttat ttgcagtggc tttggggact cagcagtggc aagtccctgt gcataatgtg     5460

aacctgcaga cttcaagatg gggcccctcc tgcacccact aacatgtctg cctttttttg     5520

tttttatcct ggaacaagtg gagaaatggc agagctggct gactctgggg acccttccct     5580

ttttcccatg gcttcatttc ttcctcacca caactaattc ggggagctga gaagtcacac     5640

agggtattcc tctcccttct ctgatgttat taattaatag accagagaat aaggttgcag     5700

atattacatt tgttgtgttt ttgtgttttg tttttttttt taaggaaaat cccaaacaaa     5760

gcccagcatg atttgagaaa agaggatgtt ttcccaggga aaataatttt tttaacctgc     5820

ctgagaatga tttatttatt tgttggaggc cattggtcag acagcctgga gcttgggctg     5880

tggaagattt caaaagcata gggctgtggt ctctggaaac ctattacagc ctgcagctgt     5940

gagctgagcc agtgacgagg tccctggaaa ctcaggaagg ctgacaggtg ggccttgggg     6000

tattggtttg tggagaagga agcattcttt aggctgcggc actccttata gtttcccacc     6060

caccgagtga cattcaggca gaaattgagc tcaggagaca gccagccttc ccacatccca     6120

cttcacttcc cggtccacac gtaaagcagt gtgtctccaa ggaggcagtg agcaattccc     6180

aaggtccccg tgttgtgaga agcgcgctgc tttctccctt tgcaggggaa aaaaaaggct     6240

ttcctggtga gatcatgagt ccttccggct tcatttctca ttgtgggttt aacttctaaa     6300

acgcaaatgg agtttagaga ggatgagcag aaccacagga cctgccccca tctctcactc     6360

actgcaattg cttctactct gggcacaagt agggtgtctg aagaccatgt ttccctctgg     6420

ttctctagtt tgcagataac acagaagaca ctggctagaa ccttaagctt tctgccaaaa     6480

agatgcagag agcagggcag tagctactgg cagtggggtg tgaataaaga gtcctttcac     6540

aaccaagttc actgaggatt tggagcacca gcttcccagc agtatcgagg ggtggagagg     6600

tgtacattca ggtggagggg tacatctagg ggtggagagg tgtacattct agaaacagct     6660

gttaacacac tccactttaa agacagcaag ctagacctgc aggatcaaag ccacacactg     6720

tggtaggggt tacaaatgtt tatggggccc agaatactag catagatgcg tgaaatggtt     6780

ggtgtgaggc aaaagggcat ggtgggggca aggatgggga ctgtggtctt actggcatgc     6840

acgtgaccta cccagaatga gcagctgcta ctcagcccca acctgtcatt gtttgtaaaa     6900

atgtaagcac agtgtagtgg aatcttccaa tttggaaggg aagccggaaa tccagattta     6960

atggaaaaaa tctgattttt caacgtcggg ttgtttgttt gtttgttttt gtttttttta     7020

acagatagtg ggcaaagaaa aattccactg ttccacgtgt acactgccag caacctctgc     7080

tctctggaga ggtggtttaa agtgagatta tgcattgccc tggtagaaga ggaaaaaagc     7140

cagcatcagg tcagggcaaa aataacagcc catgttgaac tcggaatggg gacctcttgc     7200

taagtcattc cactcctcaa gagaccattc cacagagggg ggatggatca ttcagctctc     7260

ctggtcccaa gattgtgctg aagggaagaa ggaatagaat ctggagatct ggactgctgc     7320

cccttagata tgcagaggtc cacatctgcc tggggctaca gcttgtggga ctccatcaaa     7380

ccaggccgaa atggcaaaga cagtctagga ggaggaggag gtagggtgtg aaacagccag     7440

gctctctcca aatcccaagt gttgacacag ccatcttgtc ccatccctgg aagcctcttt     7500

ggaaaccaca tagagctgtg ctggctcacg ggatgtcctg tttgcttctg cctcagttac     7560

cttactttgc ccatgggtct accacaggcg ctacctcatt gtgtctgctg agaagtttac     7620

ctgggagggg ggaacaaagt tgtccaaatc tgcttgagct gaatgtatga tctatgcaaa     7680

ttctctctct cctctctctc ttcctctctg gctctcttag aagttttttt gttttgtttt     7740

gttttgtttt gtgtttacct tgcaaacaag atactgtata ggaccctctt aagatggagg     7800

agggctttct tgcgccacct gtgtctaccc ctcacgttgt ctttggctct ggtcttacca     7860

ggcgtatgca gggagaaagt gacctctctt ccctctccac ttggctggga atattccaac     7920

tgcctctgcc tacagatacc accagaaagc gggttctgca ccttgtcatc cccctcccta     7980

acgtcatcta ctccatccct catgttcctc caacttgctt ctcccatccc tccttcaaaa     8040

acaaaacaaa acaaaacaaa agccttaggt ttctcctttt tgaaatgtgg ccttaacatt     8100

atttttggga agctgaccat ccatcctttc cctcccatct ccaccaacat cagagaagac     8160

agcatcgtga agcttctgtg gcagcctcct aaggaagggg ctgccaatct gtagttggca     8220

gatgctatag gaattgctta caaatgtcgt ctttaagaaa aatgttctta tatttttcct     8280

atgggcaaaa tgaaggcttg ggtgctcatc taaagctcag ccaactcctg aagcactctc     8340

tcagagcata ctgctgctgt aatgggctgg cttaattatc ggcagagtgc ttgaaaaggc     8400

tttgcagacc tcccctgccc ccaagactgg gtgactttat atgtacttca ttcaagggta     8460

aatcaggaga cgttctccat ttatctcttc gtccttcctg cctggaaagt gatagcacta     8520

aatattccca gcagatgggt agtgttctca aaggaatcac cctttcccta ccttcagact     8580

ctattcttta cccttccatt gctccagtgc tgatggaggc caaagacaac cccagggttt     8640

tcataggaaa ttcactggaa ttgtgcgcaa ttgtctttgt agtccttttg cctttttttt     8700

ttttaaatat tatgttgtca atagcatttg tttgggtatt tgttttagag gcctcactct     8760

aagttattac cgtccccttc attgttttca aagacatgtg gtgatatagt ttttaaaaat     8820

aactattttg ttatagatca taatatgcat aaaactgtac agaaatattt tgtaatgtgt     8880

tgattttaaa aaaaatctgt aaataaagtt ttaaaaaaag aattcaaatg gcacacgctg     8940

aaatatgtag atattttgct atttatttaa aggagtattt taagagatat tgaactatct     9000

gaaattgacc agtaatcaaa gttccaatca tctgaatgct tttccttgag gtagaatgtg     9060

agtctcagaa atgactgcat tacctgccct tttttgcacc ttttctgtct ttttattttg     9120

cagaacaaca acaacaacaa aattgtgcct tagctgtatt tttttgtcta ggggagtttg     9180

tttctgtctg acaaagcaac attttttgca gaaaacagtg gatgtattaa atactgtatc     9240

ataccaaaaa cactgcaggt gtatatagat gctttctgtc atactgtgtt ttcagatgca     9300

gaattttaaa attaaaaaaa cactgccttt atggaa                               9336


<210>  525
<211>  7204
<212>  DNA
<213>  homo sapiens

<400>  525
gggcaagctg gaaaagcgtg tgggtgagac cctcgcacaa ccccttttca ttgtctgtgt       60

gtggcgcctg cgcagtaagg gatcgttgga actgggcagg aggggatagg gtccggctcc      120

tcgccctttc ccgaggcgcc tgcgcactag gcagtcggtc tttgccgtta ccgctatgtg      180

tggggcgtgt gtggaataac gttattgccc agcggagctg agggccccgg agctcgaccg      240

cagcggcagc gacgacaaca gcggcgacga cgacgacgac gaggtggggg gaggacggcg      300

tgcgagagac tcacgggacg cgacgcgccc cgcctccccc gtccggtccc tctctccacg      360

gtaaggggat gacgtagctt tgccaaagac ttagaagcta agcagaaaat gagcttaaca      420

tcctggtttt tggtgagcag tggaggcact cgccacaggc tgccacgaga aatgattttt      480

gttggaagag atgactgtga gctcatgttg cagtctcgta gtgtggataa gcaacacgct      540

gtcatcaact atgatgcgtc tacggatgag catttagtga aggatttggg cagcctcaat      600

gggacttttg tgaatgatgt aaggattccg gaacagactt atatcacctt gaaacttgaa      660

gataagctga gatttggata tgatacaaat cttttcactg tagtacaagg agaaatgagg      720

gtccctgaag aagctcttaa gcatgagaag tttaccattc agcttcagtt gtcccaaaaa      780

tcttcagaat cagaattatc caaatctgca agtgccaaaa gcatagattc aaaggtagca      840

gacgctgcta ctgaagtgca gcacaaaact actgaagcac tgaaatccga ggaaaaagcc      900

atggatattt ctgctatgcc ccgtggtact ccattatatg ggcagccgtc atggtggggg      960

gatgatgagg tggatgaaaa aagagctttc aagacaaatg gcaaacctga agaaaaaaac     1020

catgaagctg gaacatcagg gtgcggcata gatgccaagc aagttgagga acaatctgca     1080

gctgcaaatg aagaagtact ttttcctttc tgtagggaac caagttattt tgaaatccct     1140

acaaaagaat tccagcaacc atcacaaata acagaaagca ctattcatga aatcccaaca     1200

aaagacacgc caagttccca tataacaggt gcagggcatg cttcatttac cattgaattt     1260

gatgacagta ccccagggaa ggtaactatt agagaccatg tgacaaagtt tacttctgat     1320

cagcgccaca agtccaagaa gtcttctcct ggaactcaag acttgctggg gattcaaaca     1380

ggaatgatgg cacccgaaaa caaagttgct gactggctag cacaaaacaa ccctcctcaa     1440

atgctatggg aaagaacaga agaggattct aaaagcatta aaagtgatgt tccagtgtac     1500

ttgaaaaggt tgaaaggaaa taaacatgat gatggtacgc aaagtgattc agagaacgct     1560

ggggctcaca ggcgctgtag caaacgtgca actcttgagg aacacttaag acgccaccat     1620

tcagaacaca aaaagctaca gaaggtccag gctactgaaa agcatcaaga ccaagctgtt     1680

actagctctg cgcatcacag aggggggcat ggtgttccac atgggaaatt gttaaaacag     1740

aaatcagagg agccatcggt gtcaataccc ttcctacaaa ctgcattatt aagaagttca     1800

gggagtcttg ggcacagacc aagccaggag atggataaaa tgttaaaaaa tcaagcaact     1860

tctgctactt ctgaaaagga taatgatgat gaccaaagtg acaagggtac ttataccatt     1920

gagttagaga atcccaacag tgaggaagtg gaagcaagaa aaatgattga caaggtgttt     1980

ggagtagatg acaatcagga ttataatagg cctgttatca acgaaaaaca taaagatcta     2040

ataaaagatt gggctctcag ttctgctgca gcagtaatgg aagaaagaaa accactgact     2100

acatctggat ttcaccactc agaggaaggc acatcttcat ctggaagcaa acgttgggtt     2160

tcacagtggg ctagtttggc tgccaatcat acaaggcatg atcaagaaga aaggataatg     2220

gaattttctg cacctcttcc tttagagaat gagacagaga tcagtgagtc tggcatgaca     2280

gtgagaagta ctggctctgc aacttccttg gctagccagg gagagagaag gagacgaact     2340

cttccccagc ttccaaatga agaaaagtct cttgagagcc acagagcaaa ggttgtaaca     2400

cagaggtcag agataggaga aaaacaagac acagaacttc aggagaaaga aacacctaca     2460

caggtatacc agaaagataa acaagatgct gacagaccct tgagtaaaat gaacagggca     2520

gtaaatggag agactctcaa aactggtgga gataataaaa ccctacttca cttaggcagc     2580

tctgctcctg gaaaagagaa aagtgaaact gataaggaaa cttctttggt aaagcaaaca     2640

ttagcaaaac ttcaacaaca agaacaaagg gaggaggctc agtggacacc tactaaattg     2700

tcttccaaaa atgtttcagg tcagacagat aaatgtaggg aggaaacttt taaacaagaa     2760

tcacaacctc cagaaaaaaa ttcaggacat tctacaagca aaggagacag agtggcacaa     2820

agtgagagca agagaagaaa agctgaggaa attctgaaaa gtcagactcc aaagggagga     2880

gacaagaagg aatcctccaa gtcattagtg cgacaaggga gcttcactat agaaaaaccc     2940

agcccaaaca tacccataga acttattccc catataaata aacagacttc ctctactcct     3000

tcttctttag cattaacatc tgcaagtaga atacgagaaa gaagtgagtc tttggatcct     3060

gattctagta tggacacaac ccttattcta aaagacacag aagcagtaat ggcttttcta     3120

gaagctaaac tacgtgaaga taataaaact gatgaaggac cagatactcc cagttataat     3180

agagacaatt ctatttcacc agaatctgat gtagatacag ctagtacaat cagtctggtt     3240

actggagaaa ctgaaagaaa gtcaacccaa aagcgaaaga gtttcactag cctctataaa     3300

gataggtgtt ccacaggttc tccttccaaa gatgttacaa aatcatcatc ttcaggtgct     3360

agggaaaaaa tggaaaagaa aacaaaaagt cgttccacag atgtgggttc aagagcagat     3420

ggtcgtaaat ttgttcagtc cagtgggaga ataagacagc cctcagtaga cttaacagat     3480

gatgaccaaa cctctagtgt acctcattct gccatctctg atattatgtc atctgatcaa     3540

gaaacttact cttgtaaacc tcatggacgg actccactta cctcagctga tgagcatgta     3600

cattccaaac tggaaggaag taaagtaacg aaatctaaga cttctccggt ggtatctggt     3660

tcatctagta aatcaaccac ccttccaagg ccacgaccta ccaggacttc cctcttgcgc     3720

agagcacgac ttggtgaagc ttcagacagt gaacttgctg atgctgacaa agcatctgtt     3780

gcttctgaag tatccacaac aagttctaca tcaaaacctc ccacaggaag gcgtaacatc     3840

tctcggattg atttattggc tcagcctcgt agaacacgac ttggctcact gtcagctcgt     3900

agtgactctg aagcaacaat ttctagaagt agtgcctctt cgaggaccgc agaagccatc     3960

attagaagtg gagccagact agtaccatca gataaatttt ctcctagaat tagagctaac     4020

agtatctctc gactctcaga ctccaaggtc aaaagtatga cctcagctca tggctctgct     4080

tcagtaaatt caagatggag gcgctttcct actgattatg cttccacctc agaagatgaa     4140

tttggatcaa accgtaattc ccctaaacat acccgtctac gtacttctcc agccctgaaa     4200

accactcgct tgcagagcgc tggatcagca atgcctacta gttcttcatt caaacaccgg     4260

attaaagagc aggaagacta catccgagat tggactgctc atcgagaaga gatagccagg     4320

atcagccaag atcttgctct cattgctcgg gagatcaacg atgtagcagg agagatagat     4380

tcagtgactt catcaggcac tgcccctagt accacagtaa gcactgctgc caccacccct     4440

ggctctgcca tagacactag agaagagttg gttgatcgtg tttttgatga aagcctcaac     4500

ttccgaaaga ttcctccatt agttcattcc aaaacaccag aaggaaacaa cggtcgatct     4560

ggtgatccaa gacctcaagc agcagagcct cccgatcact taacaattac aaggcggaga     4620

acctggagca gggatgaagt catgggagat aatctgctgc tgtcatccgt ctttcagttc     4680

tctaagaaga taagacaatc tatagataag acagctggaa agatcagaat attatttaaa     4740

gacaaagatc ggaattggga tgacatagaa agcaaattaa gagccgaaag tgaagtccct     4800

attgtgaaaa cctcaagcat ggagatttct tctatcttac aggaactgaa aagagtagaa     4860

aagcagctgc aagcaatcaa tgctatgatt gatcctgatg gaactttgga ggctctgaac     4920

aacatgggat ttcccagtgc tatgttgcca tctccaccga aacagaagtc cagccctgtg     4980

aataaccacc acagcccggg tcagacacca acacttggcc aaccagaagc tagggctctt     5040

catcctgctg ctgtttcagc cgcagctgaa tttgagaatg ctgaatctga ggctgatttc     5100

agtatacatt tcaatagatt caaccccgat ggggaagagg aagatgttac agtacaagaa     5160

tgactttctc ttgattgttg aaaaatcatt acctgtggaa tggctaggaa tattggaagc     5220

agcatagtgt tgatgtacgc aaaacaagac agcttggtca gctacaatct tggaatccct     5280

gtcttcttaa ttttatttat ttatttttga cgtataatgt agtatatcaa tcctttcaaa     5340

ctatttagat aaccacttga tgcacaaata ggaaaaagca gattgtggca gtgtcgcctt     5400

ttgtggtttt atgattttca aattgaattt aatgattaca ccctttccct tcatagatct     5460

tttttctttt ttttaagcca tgctgtgacc tacaagcaaa ctaaatagcc aacatttctg     5520

aacccctaag tctcctgtgc caagctgctc cctgaaatgg acttcttcat ctgtacagat     5580

ttgttaaacc attctatttg cttcttaata ataggattta tattagtact cattaccatt     5640

ggacacaatg acataagtac tctccacagt aaagcagacc tttcacaaca gtcactctgt     5700

gtcctaaaat tttccaacat agatgtgatt tatataactt tgttgatacg taaattgtct     5760

tggggtttac ggaaattaac tattatgttt gcactaagat ttgctgggag tggtaggtgg     5820

acatatctat atatcaataa ggactaaccg tcttttttgt acataggaga ttgataatac     5880

tgtatttgtt ttaagcccac agtgttttac tccactttca aaaagatcaa tttggcactt     5940

tttttcattt tttttaatgg aaataagatt tggtctctca ttttaggtta aatgataact     6000

agaaagatta aactagacag atagtttagg tggagtatat ttttaaaact cagaacatgt     6060

atattggtcc tgtgttacca agtttatatg tgacagttga aaaagaaatt cccttgaaat     6120

gatcatgagg ttaaaatttt cttcattagg ggacttggag aaccagtagt cgtaagatta     6180

gttgatagtt tcactcccaa gcaatgaatt gcttctgtgt gtttccctgt aggactcaat     6240

agtaaatgct gtctgtctta cacatttata aggaccctgc aagacgacga caaaggcctt     6300

tggcctgtgc tactaaacaa gaagcctatg aaaaatttct tctttaaact tgttttttct     6360

ctttccagta agttcacatt tggataattt taaaaagaaa agtaattacc tttgtgtttc     6420

cagaacacta taattggggt gtatcttaat tcagttaaat attattagta gacctggatt     6480

ttcccccttg accccatcag tctataaagg ttaaactgca acttttatga aatggtcttt     6540

aatatttcca caataatcct gtgctatatt tgttttaaga aacaaagtaa ctctatacac     6600

ttcaagactt tacaggattt tttaaatcct gtattgttgg atcaattaat aaagatgcaa     6660

aaaaacttta tagagatgta aaaacaaaac tataatggat ctcctatttt tctttaaata     6720

caaaaaaaaa aaggtaaatg aactattctc cttgtaaagc taaattcccc attctgtcta     6780

ataaaggaag actgaaaaaa ggttttaaag aacataaatg gaaagataca aatgctttga     6840

aggaataaac gaaatgttaa aacagggtca atccatttga agaaaaagtt ggacaaaata     6900

atcagcattg ctccctcttt tatttaatat ttgggtactg attatatcca catggaagta     6960

gaaggtaagg agtttaggaa aatactagaa tctactctgc ttacattctt gtttaagtgt     7020

ttacacagtt tggttcaatt ataaacattt ggccttttac tatgttattt ttattttgta     7080

tgaatacatt atcctcctta tttatttttg ttacatttat tacttatgtt attttgttat     7140

gcatttacaa ctccattttt aaataaagtg tttctggaac tttaaaaaaa aaaaaaaaaa     7200

aaaa                                                                  7204


<210>  526
<211>  3078
<212>  DNA
<213>  homo sapiens

<400>  526
gtagctgaga tgcagagagc catcctgccc agacctagac aactcggaag tgggtttttc       60

agcctcctgc accggtgtcg cgtctgagtg cgactgatga gccagggggc gtcggtggaa      120

gcttggggtc ggcagtctgg ttggaaagga gaggctagtg gtaacaggcc gagctggatg      180

gatgggtatg gggagagggg caggacgttc agccctggga ttctggccga ccctcgcctt      240

ccttctctgc agcttccccg cagccacctc cccgtgcaag atcctcaagt gcaactctga      300

gttctggagc gccacgtcgg gcagccacgc cccagcctca gacgacaccc ccgagttctg      360

tgcagccttg cgcagctacg ccctgtgcac gcggcggacg gcccgcacct gccggggtga      420

cctggcctac cactcggccg tccatggcat agaggacctc atgagccagc acaactgctc      480

caaggatggc cccacctcgc agccacgcct gcgcacgctc ccaccggccg gagacagcca      540

ggagcgctcg gacagccccg agatctgcca ttacgagaag agctttcaca agcactcggc      600

cacccccaac tacacgcact gtggcctctt cggggaccca cacctcagga ctttcaccga      660

ccgcttccag acctgcaagg tgcagggcgc ctggccgctc atcgacaata attacctgaa      720

cgtgcaggtc accaacacgc ctgtgctgcc cggctcagcg gccactgcca ccagcaagct      780

caccatcatc ttcaagaact tccaggagtg tgtggaccag aaggtgtacc aggctgagat      840

ggacgagctc ccggccgcct tcgtggatgg ctctaagaac ggtggggaca agcacggggc      900

caacagcctg aagatcactg agaaggtgtc aggccagcac gtggagatcc aggccaagta      960

catcggcacc accatcgtgg tgcgccaggt gggccgctac ctgacctttg ccgtccgcat     1020

gccagaggaa gtggtcaatg ctgtggagga ctgggacagc cagggtctct acctctgcct     1080

gcggggctgc cccctcaacc agcagatcga cttccaggcc ttccacacca atgctgaggg     1140

caccggtgcc cgcaggctgg cagccgccag ccctgcaccc acagcccccg agaccttccc     1200

atacgagaca gccgtggcca agtgcaagga gaagctgccg gtggaggacc tgtactacca     1260

ggcctgcgtc ttcgacctcc tcaccacggg cgacgtgaac ttcacactgg ccgcctacta     1320

cgcgttggag gatgtcaaga tgctccactc caacaaagac aaactgcacc tgtatgagag     1380

gactcgggac ctgccaggca gggcggctgc ggggctgccc ctggcccccc ggcccctcct     1440

gggcgccctc gtcccgctcc tggccctgct ccctgtgttc tgctagacgc gtagatgtgg     1500

agggaggcgc gggctccgtc ctctcggctt ccccatgtgt gggctgggac cgcccacggg     1560

gtgcagatct cctggcgtgt ccaccatggc cccgcagaac gccagggacc gcctgctgcc     1620

aagggctcag gcacggaccc ctccccttct agtgcacgtg acaaggttgt ggtgactggt     1680

gccatgatgt ttgacagtag agctgtgtga gagggagagc agctcccctc gccccgcccc     1740

tgcagtgtga atgtgtgaaa catcccctca ggctgaagcc ccccaccccc accagagaca     1800

cactgggaac cgtcagagtc agctccttcc ccctcgcaat gcactgaaag gcccggccga     1860

ctgctgctcg ccgatccgtg gggccccctg tgcccgccac acgcacgcac acactcttac     1920

acgagagcac actcgatccc cctaggccag cggggacacc ccagccacac agggaggcat     1980

ccttggggct tggccccagg cagggcaacc ccggggcgct gcttggcacc ttagcagact     2040

gctggaacct tttggccagt aggtcgtgcc cgcctggtgc cttctggcct gtggcctccc     2100

tgcccatgtt cacctggctg ctgtgggtac cagtgcaggt cccggttttc aggcacctgc     2160

tcagctgccc gtctctggcc tgggcccctg ccccttccac cctgtgctta gaaagtcgaa     2220

gtgcttggtt ctaaatgtct aaacagagaa gagatccttg acttctgttc ctctctctcc     2280

tgcagatgca agagctcctg ggcaggggtg cctgggcccc agggtgtggc aggagaccca     2340

gtggatgggg ccagctggcc tgccctgatc ctctgcttcc tcctcacaac cccaagagcc     2400

cccagcccgg tccatccacg tctggagtct ggggagagga gcagggtctt aggactctca     2460

gctctgagca tccctggcag ggtcttcaac ctctaatctc ttcccttaag ccctgtggcc     2520

acacagccag gagagacttg ccgctggctc ccgcctcatt tcagcccagg gtgctcatcc     2580

aggggcccag aacagtccca cctgtgctgc tgtgcccaca gcacaaagcc aggcttcact     2640

cccaaaagtg cagccaggcc ctggagggtg atcctgccag cagccctaca gctccacacc     2700

ctacccaccc atcggcagcc cctctgctgt tccccaggga cctctcatac actggccagg     2760

aggctgcaga acgtgtgtct ccccctccct ccaagaggtc ctgctccctc tgccagaacc     2820

gtgtgtgggc gggtgggagg gcgctcgggg cccggcccct ccctctccct gctggtttta     2880

gttggtccct atgttggaag taaaaagtga agcactttat tttggttgtg tttgctcacg     2940

ttctgcttgg aagtggggac ccctcactgc gtccacgtgt ctgcgacctg tgtggagtgt     3000

caccgcgtgt acatactgta aattatttat taatggctaa atgcaagtaa agtttggttt     3060

ttttgttatt ttctttta                                                   3078


<210>  527
<211>  4505
<212>  DNA
<213>  homo sapiens

<400>  527
tcattgtttc tgtggcgatt gcagaggctg ttgctaattg gagaagcccc actaagcagc       60

ggcagcttcc tgcttcggat cctctctctg ctgcttgcat ttaaagagca aactcgtctt      120

gtctacccac cctccctccc ccatcctccc caaaatagcc ttgtgatttc ggaagtatgg      180

actaaaatca cactcctcct taccttaccg cttggactct ggtggctccc aactcgccgt      240

cagaccccac ctgccccggt ggtgggaagc gcctggacag accatgacca cagccaagga      300

gccaagcgct tcggggaaat ccgtgcagca gcaggaacag gagctggtgg ggagtaaccc      360

tccgcagagg aattggaaag gaatagcaat tgcactgctt gtcattctgg tcatctgctc      420

cttgatcgtc acctcggtca tacttctgac accagcggaa gataatagtc tgtctcaaaa      480

gaagaaggtc actgtagaag atctcttcag tgaagacttc aaaattcatg accccgaggc      540

taagtggata agtgatacag aattcatcta cagagaacag aaaggaacag tgagactgtg      600

gaatgttgaa acaaatactt ctactgtctt aatagaaggc aaaaaaattg aatcattaag      660

agccatcaga tatgaaatat ctccagatag agagtatgca cttttttcat acaatgtgga      720

acccatatat caacactcgt atactggata ttacgtcctg agcaaaattc ctcatgggga      780

tcctcaaagt ctggacccac cagaagtcag caatgcaaaa cttcagtatg caggatgggg      840

ccctaaaggc caacagctga tatttatttt tgaaaacaat atctactact gtgcacatgt      900

cgggaaacag gccatccgtg tggtctccac tggcaaggaa ggtgtgattt acaatggcct      960

cagtgactgg ctgtatgaag aggagatttt gaagacacac atcgcacact ggtggtctcc     1020

ggatggcacg agactcgcct acgccgccat caatgattcc cgtgtcccca tcatggagct     1080

cccaacttac accggctcca tctaccccac cgtgaagccc taccactatc ccaaggctgg     1140

aagtgagaac cccagcattt ccctacacgt tattggctta aatggaccca cccatgatct     1200

ggagatgatg ccgcctgatg atccacggat gagggagtac tacatcacca tggtgaagtg     1260

ggccaccagc accaaggtcg ccgtgacctg gctgaaccgg gcgcagaacg tgtccatcct     1320

caccctctgc gacgccacca cgggggtctg cacgaagaaa cacgaggatg aaagtgaggc     1380

ctggctccac agacagaatg aagaacctgt gttctccaag gatggccgaa agtttttctt     1440

catcagagcc atcccccagg gaggacgagg gaaattctat cacatcacgg tgtcctcgtc     1500

ccagcccaac agcagcaacg acaacatcca gtccatcacc tccggggact gggacgtgac     1560

caagatccta gcctacgatg agaaggggaa taagatctac ttcctgagca cggaggacct     1620

gcctcggaga cgacaactct acagtgccaa cacggtgggc aacttcaaca ggcagtgcct     1680

ctcctgtgac ctggttgaga actgcaccta cttcagcgct tccttcagcc atagcatgga     1740

cttcttcctg ctcaagtgcg aaggtcctgg tgttcctatg gtgacggtgc acaacacaac     1800

agataagaaa aaaatgtttg acctagaaac aaatgaacat gtcaagaagg ccataaatga     1860

ccgacagatg cctaaagtgg aatacaggga cattgagatt gatgattaca acctgcccat     1920

gcagatactg aagccagcaa ccttcaccga caccacccac taccctctgc tcctggtggt     1980

ggatggcacc ccaggcagcc agagtgtggc tgagaagttc gaggtgagct gggagacggt     2040

gatggtgagc agccacggcg cggtggtggt aaagtgtgac ggccgtggca gcggcttcca     2100

agggaccaag ctcctgcacg aagtgaggcg gcggctgggc ttgctggagg agaaggacca     2160

gatggaggcc gtgcggacga tgctgaagga gcagtacatt gacaggacgc gcgtggccgt     2220

gtttgggaag gattacggtg gctacctgag cacctacatc ctcccagcaa agggagaaaa     2280

tcaaggccag acattcacct gcggctctgc tctctctcca ataacagact tcaaactcta     2340

tgcctctgcg ttttccgaga ggtacttggg cctccatgga cttgacaaca gagcatacga     2400

gatgaccaag gtagcccatc gagtctccgc gctggaagaa cagcagttcc tgatcattca     2460

tcccactgcc gatgaaaaaa ttcatttcca gcacacagca gaactcatta cacaactaat     2520

taggggaaag gctaattaca gcttacagat ttacccggac gaaagccatt actttaccag     2580

ctccagcctc aaacagcatc tgtaccggtc catcatcaac ttcttcgtgg aatgcttcag     2640

gatccaggac aaactgctga cagtcacagc gaaagaggac gaggaggagg actaagctca     2700

ggtcgctcta agcacaaacg tggctctttc tacaaccaga tgcaaccgag ggatttccct     2760

gccctccctc ttccctcgga ggggcggggc ggggcggggc cgggtgttcc atagcatgtg     2820

tgtctcggat gcggaaggca gttttgcttg ggaaacaagc tccttccccg gggtcatcac     2880

tcacggcctc catggcacca gggacaacgc tgtccccgca gcagcgcctc ctcccggcgc     2940

ccgagagacc ggcacgccac ggcccctccc ccaaggaaca gagcaaagga tggtggccgc     3000

aggccccacg cgagcccaca ggacaccggc ccctagattc cagccaccaa gcggaagcat     3060

gagacccgcc cacactagcc tctgtgttcc cgttagggac atcacaccct gtctcacgtc     3120

gcagtgccat ggacgcagca gttacagcac cattgtttta gcagtgcgtg ttcatatatg     3180

ggcttgctac ttcctgtaat gaggacgttc aacatggtga ggggctacaa gaaaacgctt     3240

ttctgtacag agtcttactg tagctacgct aatggttaac ctgatagaat taactcgtat     3300

ttttctatgg ttttaacctg atgctccact gtctccgtca tggggttgtt ttgctgtttg     3360

gggttgggcc ttgtttccct ttcctttctc cagtccacgt gtagactttg cgcttgatga     3420

agaagcagat cggaagtaac tgctccctcc tcaaggttgt cttcagacgt cttggggacg     3480

ttcctaaaca ctgaggggga agacagccaa tagcacccat taaaagaaat acctaaataa     3540

aacctctctc ccactcagct atgctagggc ttggctgtag gtgtgcactg tctatttaca     3600

tccgtcctta caaccatcct tgtcctcctt ggtaccgtat caagctcttt cccatgacat     3660

ttggtttaaa aaaaaaaaaa aaaaaaaaaa aaaaacagaa aaaagacaaa gcgtcaactc     3720

cacccacagg cccgctgtgt gtgctcgggc cacgggagtc ctgagggttc tgtgggcctg     3780

cgcgcatccc tctcccatcg tgggggtggc tccgtgacct tcctgccacg agcaggaggt     3840

tgatgatgtg ctacgttagc cttgtaagat acacccccac caaatgtgca gccggtgttc     3900

ccagtgtata tttcattctc ttgtatataa aggaagcaat gtgtgtcagg cctctgtgca     3960

gtcaacccag cctcctcccg ccagtgctaa ccccgtgttg agcctgcatg ctgacactgt     4020

ggccgatctg gactctagaa gtgctagttt gaaatatatc cattactgtc atttcctttt     4080

gagcttgtgg acaagctgaa tgtcaggact gacttcgcca gctcccagcc ctgcgggggt     4140

gtccttggca tcccatcagc agaggagatg cgtccctgtt gcattttggc gtttggggct     4200

ttgggtttat ccacatgagc tctgaacgtc cgttatagtt agggtgattg gaaggtctcc     4260

atcactgggt gttttaaagg tgattcacca ccatttgtga aaggaccaac gtgctgataa     4320

acaggaccga tccgagtgct acatgactgt gcgtttgcta tttcaatggg cctgaacgac     4380

tacaaagcca gctaggtctg gaaggggaag ccagctctgg ccacgacatc tggtcggagg     4440

gaagtgggga tgtggcatgg tagcgtctgt tcatccatgg aataaaacat tattttacca     4500

ctcgg                                                                 4505


<210>  528
<211>  5755
<212>  DNA
<213>  homo sapiens

<400>  528
gagtcgcgca cgcgcgcccg ggactgcctg cccctctctg tgacttgcct gtgtgtgtgc       60

gtgtgtgtat gtgtgtgtgt gtgtgtgtgt gcgcgcgcgc gtgagtgaga gaggagagag      120

ggagaagaga gcgcgagaga gggtgagtgt gtgtgagtgc atgggagggt gctgaatatt      180

ccgagacact gggaccacag cggcagctcc gctgaaaact gcattcagcc agtcctccgg      240

acttctggag cggggacagg gcgcagggca tcagcagcca ccagcaggac ctgggaaata      300

gggattcttc tgcctccact tcaggtttta gcagcttggt gctaaattgc tgtctcaaaa      360

tgcagaggat ctaatttgca gaggaaaaca gccaaagaag gaagaggagg aaaaggaaaa      420

aaaaaggggt atattgtgga tgctctactt ttcttggaaa tgcaaaagat tatgcatatt      480

tctgtcctcc tttctcctgt tttatgggga ctgatttttg gtgtctcttc taacagcata      540

cagatagggg ggctatttcc taggggcgcc gatcaagaat acagtgcatt tcgagtaggg      600

atggttcagt tttccacttc ggagttcaga ctgacacccc acatcgacaa tttggaggtg      660

gcaaacagct tcgcagtcac taatgctttc tgctcccagt tttcgagagg agtctatgct      720

atttttggat tttatgacaa gaagtctgta aataccatca catcattttg cggaacactc      780

cacgtctcct tcatcactcc cagcttccca acagatggca cacatccatt tgtcattcag      840

atgagacccg acctcaaagg agctctcctt agcttgattg aatactatca atgggacaag      900

tttgcatacc tctatgacag tgacagaggc ttatcaacac tgcaagctgt gctggattct      960

gctgctgaaa agaaatggca agtgactgct atcaatgtgg gaaacattaa caatgacaag     1020

aaagatgaga tgtaccgatc actttttcaa gatctggagt taaaaaagga acggcgtgta     1080

attctggact gtgaaaggga taaagtaaac gacattgtag accaggttat taccattgga     1140

aaacatgtta aagggtacca ctacatcatt gcaaatctgg gatttactga tggagaccta     1200

ttaaaaatcc agtttggagg tgcaaatgtc tctggatttc agatagtgga ctatgatgat     1260

tcgttggtat ctaaatttat agaaagatgg tcaacactgg aagaaaaaga ataccctgga     1320

gctcacacaa caacaattaa gtatacttct gctctgacct atgatgccgt tcaagtgatg     1380

actgaagcct tccgcaacct aaggaagcaa agaattgaaa tctcccgaag ggggaatgca     1440

ggagactgtc tggcaaaccc agcagtgccc tggggacaag gtgtagaaat agaaagggcc     1500

ctcaaacagg ttcaggttga aggtctctca ggaaatataa agtttgacca gaatggaaaa     1560

agaataaact atacaattaa catcatggag ctcaaaacta atgggccccg gaagattggc     1620

tactggagtg aagtggacaa aatggttgtt acccttactg agctcccttc tggaaatgac     1680

acctctgggc ttgagaataa gactgttgtt gtcaccacaa ttttggaatc tccgtatgtt     1740

atgatgaaga aaaatcatga aatgcttgaa ggcaatgagc gctatgaggg ctactgtgtt     1800

gacctggctg cagaaatcgc caaacattgt gggttcaagt acaagttgac aattgttggt     1860

gatggcaagt atggggccag ggatgcagac acgaaaattt ggaatgggat ggttggagaa     1920

cttgtatatg ggaaagctga tattgcaatt gctccattaa ctattaccct tgtgagagaa     1980

gaggtgattg acttctcaaa gcccttcatg agcctcggga tatctatcat gatcaagaag     2040

cctcagaagt ccaaaccagg agtgttttcc tttcttgatc ctttagccta tgagatctgg     2100

atgtgcattg tttttgccta cattggggtc agtgtagttt tattcctggt cagcagattt     2160

agcccctacg agtggcacac tgaggagttt gaagatggaa gagaaacaca aagtagtgaa     2220

tcaactaatg aatttgggat ttttaatagt ctctggtttt ccttgggtgc ctttatgcgg     2280

caaggatgcg atatttcgcc aagatccctc tctgggcgca ttgttggagg tgtgtggtgg     2340

ttctttaccc tgatcataat ctcctcctac acggctaact tagctgcctt cctgactgta     2400

gagaggatgg tgtctcccat cgaaagtgct gaggatcttt ctaagcaaac agaaattgct     2460

tatggaacat tagactctgg ctccactaaa gagtttttca ggagatctaa aattgcagtg     2520

tttgataaaa tgtggaccta catgcggagt gcggagccct ctgtgtttgt gaggactacg     2580

gccgaagggg tggctagagt gcggaagtcc aaagggaaat atgcctactt gttggagtcc     2640

acgatgaacg agtacattga gcaaaggaag ccttgcgaca ccatgaaagt tggtggaaac     2700

ctggattcca aaggctatgg catcgcaaca cctaaaggat cctcattaag aaccccagta     2760

aatcttgcag tattgaaact cagtgagcaa ggcgtcttag acaagctgaa aaacaaatgg     2820

tggtacgata aaggtgaatg tggagccaag gactctggaa gtaaggaaaa gaccagtgcc     2880

ctcagtctga gcaacgttgc tggagtattc tacatccttg tcgggggcct tggtttggca     2940

atgctggtgg ctttgattga gttctgttac aagtcaaggg ccgaggcgaa acgaatgaag     3000

gtggcaaaga atgcacagaa tattaaccca tcttcctcgc agaattcaca gaattttgca     3060

acttataagg aaggttacaa cgtatatggc atcgaaagtg ttaaaattta ggggatgacc     3120

ttgaatgatg ccatgaggaa caaggcaagg ctgtcaatta caggaagtac tggagaaaat     3180

ggacgtgtta tgactccaga atttcccaaa gcagtgcatg ctgtccctta cgtgagtcct     3240

ggcatgggaa tgaatgtcag tgtgactgat ctctcgtgat tgataagaac cttttgagtg     3300

ccttacacaa tggttttctt gtgtgtttat tgtcaaagtg gtgagaggca tccagtatct     3360

tgaagacttt tctttcagcc aagaattctt aaatatgtgg agttcatctt gaattgtaag     3420

gaatgattaa ttaaaacaca acatcttttt ctactcgagt tacagacaaa gcgtggtgga     3480

catgcacagc taacatggaa gtactataat ttacctgaag tctttgtaca gacaacaaac     3540

ctgtttctgc agccactatt gttagtctct tgattcataa tgacttaagc acacttgaca     3600

tcaactgcat caagatgtga catgttttat aaaaaaagga aaaaaaacat ttaaaactaa     3660

aaaatatttt taggtatttt cacaaacaaa ctggctttta aataaatttg cttccatatt     3720

ggttgaataa gacaaaaaca attaaactga gtgggaagtg aataaaaaaa ggctttaggt     3780

atcgattcca tatttttcaa agccaaatat gtaaatgcta aggaaagtaa acaaagagga     3840

gattccaatc ttgtaattta atattgttat taaaacttta atgtatccta ttctttaaca     3900

tttggtgtta atataaaatt acttggcaat gcttgacatt tgaaataaac atttttctat     3960

tgttttattg caagtggtcc aattaatttt gcttagctac agtttggtca taaatcaagt     4020

gagtttaaag acactaccaa gttgttaggt gcccagagaa aatttctccc ttttaaaaag     4080

gccaggtgat ttttcaaatg taatcttgcc cccaaagtaa tatctgaata tctttttgac     4140

atgtctaaat atatatatat ataaagaaat atttgttaac acaaaagcat ttgatctatg     4200

tagataaatg ctaatagatt taaaaagcta atattaacaa ataccagaat acgtgaagtt     4260

ccatttttaa agtgtttgag cttacagaag agaaacattc attttaaatg aagtaaaaaa     4320

tgccttgaaa gtaattcttt agatagttgc ccattgatta aattccaaaa actaaatatg     4380

tttttagctt taaaattata aaagctgtca taaactttat atattatgaa ttttaaaata     4440

tgtttgagtc tcctgcaata tagtttcatc ccattgacat caattaaaaa taaccctaat     4500

atattatttt tatatttatt cctcaggtgg aatggctatt ttaatatgcc cagtgtggat     4560

aaaatgtcac atttctgtaa cttttgacta aagagcctat atttatctag ttaatgaatt     4620

taaaggatct atctttccct tcataaaata cctcttattt ccattaaagc cccccaagtt     4680

taattaattt aggattttga atgattattg acatccaata gttattttta atatttgtat     4740

tcttgttatt tctggaagaa agcctttgtg tagcacttgg tattttgcaa agtgctttta     4800

aaacattctt acttaccgta tttcatagaa gggaaggaaa aatgtaaggt ttaacagtaa     4860

gcacttgcat tgaacatgga ggcatgtggt atcatgatat tcttcactaa atttagctgt     4920

ccctaatcac agatcctaag gtaatataat ataattttag tgcatttctc ctcatcagga     4980

atgctggagg tgcattttaa gttttaataa taagtgctag aatgaccaaa ttgcagacta     5040

attgtttcca tattgtactt aaaatgagtt tttaaaagtg aaaaagaaat gactatatac     5100

aatcaatgct atttattgta cctctgggcc tactcttcta aaaattgtag cttatcgatt     5160

tttctctgtc aagcttgaac taatgtaaat aattgaaata atgtaaagtt atattttcat     5220

gtttttatag atacaacatg acaagaatac ataatgtaag agtatttcaa ctatggataa     5280

tgttgattgg ataatgcaca tctcagttac aagcagtact catagtttaa tatccatgta     5340

acggtgcatc aatatattgc tatataaata tgtctgtgtg catataagtg aaaagtggtc     5400

aaacaagagt gatgacagct gtctaaaggt ttttttattc attttatata aaaactgtta     5460

tggaaagacc aaaatgttta tgaactattc ttatgtaaat ttacaattgt cctttactgt     5520

acttttttgt ttacagtata gtaccttatt ttctgctgtg ttaagtgggt gtcaaactcc     5580

aagaagacat acactttcta taacttctat tgaagatatt ggaatttcca atttttcatg     5640

tgtactatgt cagaaaatgc tttcgatttt atttttaaat ctaacatcgg atggcttttc     5700

cggagtgttg taaaaacttc aatcatacat aaaacatgtt cttacaaaag gcaaa          5755


<210>  529
<211>  560
<212>  DNA
<213>  homo sapiens

<400>  529
tgcgtgccgc cgttgatccg gtgctgcagt gaggaggtgg ttcttgcccg tgttgtgtgt       60

gtgtgtgagt gagagagcga gtgagtgagt gagtgagtgt gtgtgtgggg gggactcggc      120

ttgttgttgt cggtgacttc cccctcccct tcaccccttc ccctccccgc cgccgctgca      180

gtggccgctc cctgggccgt aggaaatgag cgataacgat gacatcgagg tggagagcga      240

cgaagagcaa ccgaggtttc aatctgcggc tgacaaacgg gctcatcata atgcactgga      300

acgaaaacgt agggaccaca tcaaagacag ctttcacagt ttgcgggact cagtcccatc      360

actccaagga gagaagggaa caaagatgaa gttaaccctc ccacctgtct ttccttatga      420

acacttgcct tttccaactg ttttctgcca tggctaatca gaaaaagttt cttaaggaaa      480

tggtggcaaa aaaaaaaaaa aaaagacaca aaggtaacaa acaaagctgg acctatttat      540

aatgttccag taagcagaag                                                  560


<210>  530
<211>  2784
<212>  DNA
<213>  homo sapiens

<400>  530
ctccctcccg ccggccgggg tgcgcgggcg gcggggcggc ccgcgggcca tgcgttcggc       60

gcggcccagc ccggccggcc gggggcggcg ccccgagccc gggccccgcg cggcccgcgc      120

ccccggcccc cgctgagccc cgggggcccc gctgcggccg aggccatgtt cccggtgttt      180

ccttgcacgc tgctggcccc ccccttcccc gtgctgggcc tggactcccg gggggtgggc      240

ggcctcatga actccttccc gccacctcag ggtcacgccc agaaccccct gcaggtcggg      300

gctgagctcc agtcccgctt ctttgcctcc cagggctgcg cccagagtcc attccaggcc      360

gcgccggcgc ccccgcccac gccccaggcc ccggcggccg agcccctcca ggtggacttg      420

ctcccggtgc tcgccgccgc ccaggagtcc gccgcggctg ctgcggccgc tgccgccgct      480

gctgccgccg tcgctgccgc gcccccggcc cctgccgccg cctctacggt ggacacagcg      540

gccctgaagc agcctccggc gccccctccg ccacccccgc cagtgtcggc gcccgcggcc      600

gaggccgcgc cccccgcctc cgccgccact atcgccgcgg cggcggccac cgccgtcgta      660

gccccaacct cgacggtcgc cgtggccccg gtcgcgtctg ccttggagaa gaagacaaag      720

agcaaggggc cctacatctg cgctctgtgc gccaaggagt tcaagaacgg ctacaatctc      780

cggaggcacg aagccatcca cacgggagcc aaggccggcc gggtcccctc gggtgctatg      840

aagatgccga ccatggtgcc cctgagcctc ctgagcgtgc cccagctgag cggagccggc      900

gggggagggg gagaggcggg tgccggcggc ggcgctgccg cagtggccgc cggtggcgtg      960

gtgaccacga ccgcctcggg gaagcgcatc cggaagaacc atgcctgcga gatgtgtggc     1020

aaggccttcc gcgacgtcta ccacctgaac cgacacaagc tgtcgcactc ggacgagaag     1080

ccctaccagt gcccggtgtg ccagcagcgc ttcaagcgca aggaccgcat gagctaccac     1140

gtgcgctcac atgacggcgc tgtgcacaag ccctacaact gctcccactg tggcaagagc     1200

ttctcccggc cggatcacct caacagtcac gtcagacaag tgcactcaac agaacggccc     1260

ttcaaatgtg agaaatgtga ggcagctttc gccacgaagg atcggctgcg ggcgcacaca     1320

gtacgacacg aggagaaagt gccatgtcac gtgtgtggca agatgctgag ctcggcttat     1380

atttcggacc acatgaaggt gcacagccag ggtcctcacc atgtctgtga gctctgcaac     1440

aaaggcttca ccacggcagc atacctgcgc atccacgcgg tgaaggacca cgggctccag     1500

gccccgcggg ctgaccgcat cctgtgcaag ctgtgcagcg tgcactgcaa gacccctgcc     1560

cagctggccg gccacatgca gacccatctg gggggggccg ccccccctgt cccgggagac     1620

gccccccagc cacagcccac ctgctgaggg ggacccccgc acccaccagg tactggtgag     1680

gtttgtccaa tggcggcggc agcggcagcg gcggcagcgg cagcagcggc agcagtagca     1740

gcccctccca cagctgtggg ctccctctcg ggggcggagg gggtgcctgt gagctctcag     1800

ccacttccct cccaaccctg gtgagctcca agttggttgc gggggagagg ggagaatgga     1860

gtagagtccc ttggtacaag ctcctctccc ccctcttttc ccaccaactc ctatttccct     1920

accaaccaag gagcctccag aaggaaagga ggaagaaatg ttttcttagg ggaattcgct     1980

aggttttaac gatttgtttc tcctgctcct cttctatcag acctgacccc acacaaacct     2040

gtcccctcgg ttgtgttgaa gtcccctgga cagtgggcag gggtggcaga ggacacgagc     2100

agccactgcc cgtaccccct ctcctctctg taagcccatg ccctgtcttc ccagggactt     2160

gtgagcctct tccctcgacg gtcctcttct ctccttccag tcctctcccc ctgctgtctg     2220

cagcccctcc ccggggagtt ggtgctttct tttccttttt tttttttttc cagggggagg     2280

gaggagagga aggaggggga tcagagctgt cccaaagagg gaaagcggtg aggtttgagg     2340

aggggcagaa gcagggccgg caaaggttgt accttcataa ggtggtatgg ggggttgggg     2400

tcaggccctg aacatcgtcc tacttgagaa tctgtcaggg gaaaaagtca aggggagcag     2460

gaggaagagc caggagggcc agaggcagag aagagatgga gtcttagggg ccagggtgag     2520

cgaggggtcc agggcctaga ggtgcttcct gggggcgggg gaatgcagcc agtgtccccc     2580

tcccctcttc caccccagct ccagccctgg tcttgtcttt tcatccctct tccccacgac     2640

agaagaagtt gtggccctgg ccatgtcatc gtgttcctgt gtcccctgca tgtaccccac     2700

cctccacccc ttccttttgc gcggacccca ttacaataaa ttttaaataa aatcctgttt     2760

ctggctctgg attgaaaaaa aaaa                                            2784


<210>  531
<211>  6351
<212>  DNA
<213>  homo sapiens

<400>  531
cggcccagcc gagccgggct gcttgtctgg ccggcggagg ctgagcgcga ccctagcaag       60

ccgcggcgcc cgccgaccag ggacaagagc gactcctggg accccactct gccccgcgcc      120

gccgcctcct cccctgttgt cgcggggacg ctcaggcccg cgccgcccgg gccacgattc      180

tcctcctctt tctcccggag gggaaggaac ggagaaagcc gagcggcggc tccgggagag      240

agcgagccga ggcccctgcc cccgaggctc ggggcaggag gaggaggagg aggaggaggc      300

ggaggcggag ggaagtgcgc gtcactctcg ggaggagagt atttcacctc caggcagagg      360

ctgcggctgc cagttgagta cgagcggcag ctgcgggcgc cggcaatcga gtggcttcct      420

ggccatggag aggagatctg gacccgagga cgccagggac tcctctccgt ctccctggac      480

cgctgtgtag gcacctgagt taacggacgc taagcggggt aggggaagta acagtgtatc      540

atgtatgcca ctgattccag gggacactcc cctgctttcc tccaacctca gaatggaaat      600

agtcgtcacc catctggcta tgttccaggg aaggttgtcc cattgcgtcc ccctcctcct      660

ccaaagagtc aagcttcagc caaatttacc tccatcagac gagaagaccg ggcaaccttc      720

gcattctcac ctgaagaaca gcaagcccag agagaaagtc aaaagcaaaa gagacacaaa      780

aatactttca tttgttttgc tattactagt ttctcatttt ttattgcact tgcaatcatt      840

ttaggaatat cctcaaaata tgctccagat gaaaattgcc cagatcaaaa tcctcgtctc      900

aggaattggg atccaggaca agattctgca aagcaagttg ttatcaagga gggagatatg      960

ctccgtctga cctcagacgc caccgtgcat tctatagtca ttcaggatgg aggactgctt     1020

gtatttgggg acaataaaga tggatccaga aatattactt tgaggactca ttacatcctg     1080

atccaggatg gtggggcgct tcatattgga gcagaaaaat gccgctataa atccaaagcg     1140

acaattacct tgtatggcaa gtcagatgaa ggtgaaagta tgccaacatt tggcaaaaag     1200

tttattggtg tggaagctgg cgggacactg gagttacatg gggcacggaa ggcatcgtgg     1260

acgttgttgg caaggaccct gaattcctca ggcttgccct ttgggtccta tacctttgaa     1320

aaggactttt cccggggcct caatgtgagg gtcattgacc aagacacggc caaaattttg     1380

gaaagtgaga gatttgatac ccatgaatac cgcaatgaga gcaggcggct tcaggagttt     1440

ctgagattcc aggatccagg tcggattgtt gccatagctg tcggggattc agccgctaaa     1500

agtctcttac aaggaaccat ccagatgatc caggaacggt tgggaagtga actgatccaa     1560

ggactgggct acaggcaagc ttgggcttta gttggtgtca ttgatggtgg aagcacttct     1620

tgcaatgaat ccgtgagaaa ctatgaaaat catagcagtg gcgggaaggc tcttgcccaa     1680

agagaatttt atactgtgga tggccagaag ttctctgtga cagcttatag tgaatggatt     1740

gaagaaaccc ctcagttcct gcacatgggt gagatcatag acggtgtaga catgagagct     1800

gaggttggaa ttcttacccg gaatattgtg atccaaggag aagtggagga ctcatgctac     1860

gcagaaaatc agtgccaatt ttttgattat gatacctttg ggggacacat tatgataatg     1920

aaaaatttta cttcagtcca tctttcttat gtggaattga aacacatggg tcagcagcag     1980

atggggcgat accctgttca ttttcacctg tgtggtgacg tggattataa aggaggatac     2040

agacatgcaa catttgtgga cggcctgtct attcatcaca gcttctcaag gtgcatcact     2100

gtgcatggga caaatggctt gctaataaaa gacaccattg ggtttgacac actaggtcat     2160

tgtttctttt tggaagatgg tattgaacag aggaatactt tgttccacaa tctgggactc     2220

ctcaccaagc cgggtactct cctgcccacc gataggaaca actccatgtg taccaccatg     2280

cgagataaag tgtttggaaa ttacattcct gtgcctgcta ctgactgtat ggctgtttca     2340

actttctgga ttgctcatcc caacaataat ctgattaata atgcagctgc aggctcacag     2400

gatgctggaa tatggtattt attccacaag gaaccaactg gggaatccag tggattgcag     2460

ctcttggcaa aaccagaact cactccattg ggtatatttt ataacaacag ggtccattca     2520

aattttaagg ctggcttatt tattgacaaa ggtgtcaaaa caaccaactc tagtgctgct     2580

gacccaaggg aatacctctg tttggacaat agtgcaagat ttcgacctca tcaggatgca     2640

aaccccgaaa aaccacgtgt tgctgctcta attgacaggc tcattgcttt taaaaataat     2700

gataatggag cttgggtcag aggaggagat attatcgttc aaaattcagc atttgcagat     2760

aatggaatag gactgacctt tgccagtgat ggaagcttcc caagtgatga aggttccagc     2820

caagaggtat ctgaatctct ctttgttggg gagagcagga attacggctt tcagggtggt     2880

cagaacaagt atgtaggcac tggaggaata gaccagaagc ctcgaacatt acccaggaac     2940

aggacgttcc caattagagg ctttcagatt tatgatgggc ccattcatct cacaaggagc     3000

actttcaaaa aatatgtgcc aactccagat aggtacagca gtgcaattgg cttcctcatg     3060

aagaattcct ggcagataac ccccaggaat aatatctccc tcgtgaagtt tggtccacat     3120

gtctctctga atgtcttttt tggaaagcct ggtccctggt ttgaagattg tgagatggat     3180

ggtgataaga actccatatt ccatgacatt gatggctctg tgacaggata caaggatgct     3240

tatgtgggaa gaatggacaa ctacctgatc cgccatccaa gctgtgtaaa tgtgtctaag     3300

tggaatgcag tgatctgcag tgggacctat gcacaggtct atgtacagac atggagcact     3360

cagaatcttt ctatgaccat tacacgagat gagtatccgt ccaaccctat ggtgctccga     3420

ggtattaatc agaaggctgc ctttccacag taccagcctg tcgtcatgct ggagaagggt     3480

tataccatcc actggaatgg gccggcacca cggactacat ttctatacct cgtcaacttc     3540

aacaagaatg actggattcg agttggcctt tgctatccat caaacacaag ttttcaagtt     3600

acctttggct atttgcagcg gcagaatggc tcattatcca aaatcgaaga atatgagcct     3660

gtgcattcac tggaagaact gcaaagaaag caatccgaga ggaaattcta ttttgactcc     3720

agcacggggt tactgttttt gtatctcaaa gccaaaagcc acaggcatgg ccacagttac     3780

tgttcatctc agggatgtga aagagtcaag atccaagcag ccacagactc aaaggacatc     3840

agtaactgca tggccaaagc atacccacag tactacagaa agccgtcagt ggtcaagcgg     3900

atgccggcca tgctcactgg actctgtcaa ggctgtggca ctcggcaggt ggtgtttact     3960

agtgatcctc ataaaagtta cctccctgtg caattccagt cacctgataa agcagaaacc     4020

cagcgtggag acccgtctgt tatttctgtc aatggcactg actttacctt ccgaagtgca     4080

ggcgtcctcc tccttgttgt ggatccgtgc agcgttccat tccgcttgac ggaaaaaacg     4140

gtttttcctc ttgctgatgt cagtcgcatt gaagagtatt taaaaacagg catccctcca     4200

aggtccattg ttctgttgag cacaagagga gaaataaagc agttaaacat ttcacactta     4260

ctagtacctc tgggattagc caaaccagct catctttatg acaaagggag taccatattt     4320

ttgggattca gtggaaactt taaaccatca tggactaagc tatttaccag tcctgctgga     4380

cagggccttg gggtgcttga acaattcata cctttgcagc tggacgaata tggttgtccc     4440

agagccacca ctgtccgcag aagagacctg gaactgctaa agcaagcttc aaaagcacat     4500

tagagactaa ctgtaactta agtgctgggg gaaaaaaaat gtgaactaac ttatttaatt     4560

tatggcattt taaaatgaca ctgttaaccc aacggaacca ttttccagtt tgatacagaa     4620

tggggagaaa agaaagcgtt tgaaattatt gcttggatac cagcttcatg caccttctag     4680

ttgtacaaaa tgttaaagac gttgtttgta tttgtaaggc tggtgtattc agagagcaga     4740

tctcttattc ctcactttcc acccccgtat tttgtaatga ccatgagcaa tgtttttact     4800

ttttgtataa tggggtgggg tggagtgggg gcttctgaga gtcagcctga ggtctttaga     4860

ggaccagcta ttgtagcacc ttggatactt gaagtttaat gctcagttgg gtcgggtggc     4920

agttgacttg gtggctggca tgttcagcag tgcctggggc cctgtttctg ggcagccttt     4980

gaggattttc tatgatattg aatgacagtt ttaagtggca actcaggccc agctcatgcc     5040

cttttttgcc tggacatgtg ctatttttat tcacttatat atcaattact tgtaagggtt     5100

aaactttcaa acaggaagta tattgggaca aaagggctct tggggattag atatcccttt     5160

aatctgtgac cattgggcaa aaaattttcc tgcagcaaaa gtctgaggct gttgggacca     5220

tttttgcagc tttaatcctt agcctctttt gactgtatat ttgtgtttaa aatgcagagc     5280

tcaactgaat atttcctttt ttgttttgtt ttgttttgtt ttaagaagta ggttgttttc     5340

ctgaaccgta aacttgtatc attttaactt gcacaaagga agtctgttct tggtattgct     5400

cttgcacttg ggttttttgt tattgttttg tgtggatttt ttaaagcttt tctgttcacc     5460

ctcctgccag gaaaatccca gaaagcttaa tgatacccca aaatgattac acccagggag     5520

gaaaaaaagg agcgctttct agggtcagaa tcgtggagag aatactcaga aatgaacctc     5580

tttaaagcct tgcaggaatg agtcactctt acttaatgaa atgttaaagc caattaaaaa     5640

gcatgctgtg atgcccagct tccctttcca cagggtgcat gcgtctcctg ctggtgaatc     5700

acatgcggca agaggcaact ggctccacag cctgggatgc tgccgtacca agaggaaaga     5760

agcagcaaaa tgcctttacg ttgttctaaa cccccgacgc ataaagtgta gaggagggat     5820

ggccaagggt gggtggtaga aagtgtgttc aggctgacac tggcaatgag tacagataat     5880

ttcactttcc tcttctaggg gcaaaggctg atggcctcta cctttgtatc caggagaaac     5940

tgcagagcag ccctgtgact ttacaaaata tgctacctca aagtgctacc gataaacctt     6000

tctaattgta agtgccctta ctaagggcac atgtcttaat caaagttagt tttttgtttt     6060

ctggtttgtt tttttttttt gtatattgat gaatgagatc ttacctatta aatatattat     6120

tggattatgg ttcctgaagg tcattagagt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt     6180

tttatgactt aaatatcttt acgtgtgttt tttagagctt ggttctttaa agatttggag     6240

aagatatgta aattaccaag gcacttggtt tttctgtttt atatactaat aatcagggcc     6300

taagttaaat aaaaatatgt gtgcatgtat tttaaaaaaa aaaaaaaaaa a              6351


<210>  532
<211>  1077
<212>  DNA
<213>  homo sapiens

<400>  532
ggcggtccgg gcgggtgact ggcggcgggc gccgcggtcg ggctggctgc cgggcagcat       60

ggaggagctg agcagcgtgg gcgagcaggt cttcgccgcc gagtgcatcc tgagcaagcg      120

gctccgcaag ggcaagctgg agtacctggt caagtggcgc ggctggtcct ccaaacataa      180

cagctgggag ccggaggaga acatcctgga cccgaggctg ctcctggcct tccagaagaa      240

ggaacatgag aaggaggtgc agaaccggaa gagaggcaag aggccgagag gccggccaag      300

gaagctcact gccatgtcct cctgcagccg gcgctccaag ctcaaggtgg gtggctgcgc      360

tgggtatgct gaccccacct cccagcaccc ccttggcgta gggggcaggc agagggaggg      420

tttggggccc tcaggaaggg ggtggcactt ctgccaacag tctgtccctc tactcggaaa      480

acaggagccc cctttcttcc tgtctctcag cttctgctgc caggggcccc agccggctga      540

gagttcctcc ccgcccctcc caggggcttc ctgcttcagc ctgtcctgca cgcctctctg      600

ctgggtggca gggtcaaact gctgcagaca agcactcttc cctcccaggg ggtccttggg      660

ggacggaaag gaacaggaag catgcgtaca gtaggtgctc ataggattgc cggctggatg      720

tgactcaaaa gcctaagatt tgggggctac tccgggccca cctgcgggtg caccttaaat      780

cgaggtggcc acgaaaggca gggctgactg aatagccagg gggtgccagg aggggccttg      840

gaggagggca gaggcagtgt gggctgatga tgtgctttgg ccttctcggg actgtcctgt      900

cacccctcct cgctacagtg atgggctcac cccgccacag gtatgcatgc gcccctgggg      960

tccgtggtag ggcccctccc tcccctgagg acaggtgagg caggacagga tgggggagga     1020

gggcctggcc tcagtcccgg gtgtggcttt gattccctcc tccgggcact gtccctg        1077


<210>  533
<211>  7064
<212>  DNA
<213>  homo sapiens

<400>  533
gtgctgaggg ggcgcggcgc ggaggggcgc ggagcggcgc ggagccgggc ggctcggggc       60

ccagagagag ccgcggccgg gagctcgcgg gctcctgaca acctcctccc ctcggcggac      120

gacgaccacg gcgactaggg cgccggtcat ggcggagcaa caaacccggc gcggacccta      180

ggcaccaccg catggagcgg gacgaaccgc cgcctagcgg agggggaggc ggcgggggct      240

cggcggggtt cctggagcct cccgccgcgc tccctccgcc gccgcgcaac ggtttctgtc      300

aggatgaatt ggcagagctt gacccaggca ctatttctgt ttcagatgat cgggctgaac      360

aacgaacctg tctcatttgt ggggaccgcg ctacaggctt gcactatggg atcatctcct      420

gtgagggctg caaagggttt ttcaagcgga gcatttgcaa caaacgggta tatcgatgca      480

gtcgtgacaa gaactgtgtc atgtctcgga agcagaggaa caggtgccag tactgccgcc      540

tgctcaaatg cctccagatg gggatgaacc ggaaggctat cagagaagat ggcatgcctg      600

gaggccggaa taagagcatt gggccagtcc agatatcgga agaagaaatc gaaaggatca      660

tgtctgggca ggagtttgag gaagaggcca atcactggag caaccatggt gatagtgacc      720

acagttcccc tgggaacagg gcttcggaga gcaaccagcc ctcaccaggc tccacactgt      780

cttccagtag gtctgtggaa ctgaatggat tcatggcctt cagggaacag tacatgggaa      840

tgtctgtgcc tccacattac caatatatac cgcacctttt tagctattct ggccactcac      900

cacttctgcc ccaacaagct cgcagcctgg atccccagtc atacagtctg attcaccagc      960

tgttatcagc cgaggacctg gaaccattgg gcacgcccat gttgattgaa gatggatacg     1020

ctgtgacaca ggcagaacta tttgccctgc tttgccgcct ggccgacgag ctgctcttta     1080

ggcagattgc ctggatcaag aaactgcctt tcttctgcga gctctcaatc aaggattaca     1140

cgtgcctctt gagctctacg tggcaggagc taatcctgct gtcttccctc accgtttaca     1200

gcaagcagat ctttggggaa ctggctgatg tcactgccaa gtactcgccc tccgatgaag     1260

aactacacag atttagtgat gaagggatgg aggtgatcga gcggctcatc tacctctatc     1320

acaagttcca tcagctaaag gtcagcaacg aggagtatgc ttgcatgaaa gcaattaact     1380

tcctaaatca agatatcagg ggtctgacca gtgcctcaca gctggaacaa ttgaataaac     1440

gatactggta catttgccag gattttactg aatataaata cacacatcag ccgaaccgct     1500

ttcctgatct catgatgtgc ttacctgaga ttcgatatat tgcaggaaag atggtgaatg     1560

tgcccctgga gcagctgccc ctcctcttta aggtggtgct gcattcctgc aagaccagtg     1620

tgggcaagga atgacctgtt ccaggcgccc tcctcaggcc aaccacagcg tcttgggtgg     1680

gcaggacagg ctctggaggg aaaagccaga gagaccaaga tggaggctgt ggagcagcat     1740

ttcccgttgc ctccatagca agaagagttt ttgtttgttt gtctgttttt ttaacctcat     1800

ttttctatat atttatttca cgacagagtt gaatgtatgg ccttcaacat gatgcacatg     1860

cttttgtgtg aatgcagcca atgcattttc ttacagttta cagaatgtga agatgtttaa     1920

tgttacagtg ttgtcattgt ttagaaatag ttcttttgta ttttgaggga gagggtggga     1980

tggggctaag atgactattt ccataatgtt gacaaagatg actacctcaa tggaaatggg     2040

gggtgtggcc atccctactt tttccacatt ttctcagcag actcatacat ttgtctgtca     2100

gagagcaaat tgcctttttt agccacagaa ttgccagata aaacggcaca ctgtaagggg     2160

gcaaagtgtt gttaggagat tcactaagca aggttggtga gacggcaaca gggtaggagg     2220

tgaggattga gccacgtcct ttccttggaa agcgtgaaaa ttaagagagt agggcacagt     2280

gaccatattt aaggcaggtg tccttccacc caacaagtcc taagggcaga agaatttctg     2340

ttctcacacc ttgctgcccc ccttacccct gcaccaccat cattgtctac cactgcgaac     2400

tttccatcta ggcaaagtcc tggcaatcac ttgatccaca ggactcgcct cccagctccc     2460

tcggggcccc cagctaccta gtttccttac ctggatctcc tgaggcccac cttcctcctt     2520

cccactccct tacacatttg acttcctatt ggccctttga aaaaccagct gagcagaatg     2580

ccatgttctg aagcctggtg cccactactg atttattctc ctttcacctt gttttcttca     2640

aagggtagta gggcaaggcc agactgcaaa aagaatagac actccccttt tgaaatctgt     2700

tcctctcccc tccccttcct accgcaccct caggtctaaa tccgaaaact tcaggctttt     2760

ttaaacaatg agaaggacca ttcacctgtc tgctgaccag aaatgttgcc cctaagttct     2820

tctccaagtt ctccttttct ctccagagtg agaccagttt tcctcaggga cccaggacac     2880

aaagcccaag gcccagagtg gctcagctgc cccttacttc agcagtggac tggccagcca     2940

aggcctggag ggctggagcc agaagcacct ggaagggaag gggggcttta aactacctca     3000

ggttcctaat ggcccggctg ctacctctgc agacatggcc tggactcctt gacctctcac     3060

tacctgcccc accttatccc aggacgtgtt ccttaccctc ttgactttgg ccagcgctac     3120

accaggtctg tctttgaact ctttcaggtg cttgtcctgc ctacacccag gtatctttca     3180

cagccagtgt ggcaagcaga ccacttagtt ggctgcatgc ctgggtaggt tggaagggcc     3240

cacggcacct tcttctgcct atttagtcaa aggctgtttg ctgtctcctc aactcaacct     3300

agtaaagcta cccaggaggg caccacgtcg tgtgcatact gggtagtcca tgtctgattg     3360

taattgtttc tttctggtga aatgttacgg gtaccagcag agtgatgatt ttggcccttg     3420

atggatctaa aactcggaac attactcctc aatgccgttt ccccagttgc tctgagaagg     3480

aagagacatg ttcctcagga aaagctccag ctagcatgtt tttcacgtca gtgggaagat     3540

tcttgtgtgt tcgtgtgtat ctgtttattt ctaagttcac gatacttgtt cccctgaatt     3600

ttatttaacc aactagatca cattctttgg ccacaggtca gactctgagc tgctttcctc     3660

cagatcggga aggagacaca tatcacagat gccttctcta agacagctcc tgtgtacagc     3720

atcgttcttt gctgaggcct ctatctgtcc aattattatt tttgaaattg cttttcaaat     3780

taaacatttt acccgttgtg ttgggtgtca aaagaaattg ctctctgatg aggcaagaac     3840

atgtctctcc aacaacgtag tattgaacag agcaagttgt taatttgtgg agtaggggaa     3900

aggttctgca agttgccatt gtacaaatcc agttttacaa atgtttgcag cagattccac     3960

agaacaaaga gcccattcat tgccgagagc cctgcagaat ctcagagcaa agtggctgtg     4020

tgttccgagc cggagcctga cctgtggacc gtctttaatg tcttctgcac cagtcctttt     4080

atgacgtggg ctttttttaa acagggtaaa gtgaatgtgt tgcattgcaa actcaggtat     4140

tatgaggaga aggtaggagt gtagctagca gcgtggagac attaggtcag ccactagatg     4200

tatttgtgaa tttggtttga aggacacgga gaaaggttgg aggggaggtt tggtgtgttt     4260

gttttttgct ttcttcccca taatgtttgg ttaacaggta gcctttttgc gagtggaagg     4320

agagaaaagt tgtgcatgtt ttctctaatt tctctttctg ccctctctct gatccccaac     4380

caccaaaagc actcactttg agtgaggatt tttttttttt tttttttttt tttttttgag     4440

gcggagtctc gctctgtcgc tcaggctgga gtgcagtggt gcgatcttgg ctcactgcaa     4500

gctccgcctc ccgggttcat gccattctcc tgcctcagcc tcctgagtag ctgggactac     4560

aggcgcccgc caccacaccc ggctaacttt ttttgtattt ttagtagaaa cattgtttca     4620

ccacgttagc caggatggtc tccatctcct gacctcgtga tccgcctgcc tcggcctccc     4680

aaagtgctgg gattacaggc gtgagccact gcacccagcc gagtgagaat ttttatgcca     4740

taaaaatacg actctgaaag ctacatggaa aaggagaatc ccacctcctt gcactacatt     4800

gaaacatgca agcctttccc tccctctcct ttttgatgtt ttcttgtccc aagacaaaag     4860

tttggcatct tggaacttat tcatgctctc tggctgcctt tgtagacttt tggagtcctt     4920

tgcaaggttt ggtggtctcg tcgttaatct ggagaaattc cccagaatct gtctcaaagc     4980

gctcaacctg gctcagagga cacccagccc ctatgcccca ctcacaagag aggtgggcaa     5040

gcccccaggg ataggaggaa gtaagcagga tcctccctgt cctgtttccc agaaccagag     5100

caaggaatgg ggaatcctaa gggtttctgt ggcatcactg aatgtcaccc actccacatc     5160

aacctgcctc tcacctgcca ccctttttca gggaggtgag tacctgccat ggtcactgtt     5220

accagatcct taaaatcctg ggctctgagc taggtgcatt gctctgttac ccatttccta     5280

catttgtttg tttgttcttg atttcctggg ggaatgggac tgatggagac agacaaaccc     5340

actgtgggca gcatctaagc catgtccaag gttggtcgaa ttaagggaac cctggcctct     5400

cagcaggaca gaaagctgag ctgtggttcc aggccctcct ctctgggccc ctggtgtgta     5460

tcttttttcc ttgttgcttt tgaaattttt gcaattattt taagaatcca gtctttcaga     5520

ccagcccttt tattaagctt tgaattttta attgattttt ttaaagtaaa aaaaaaaaaa     5580

acccaaaaaa caaacaaaat ttaacaaaaa aatccgctac tcttactccc ctgcctcccc     5640

ctaccccagc ccatgagagt tcccttgcac tcccctctgc ctttgcaact gatcatcctc     5700

cctttctcct tggcttgaag catctatgtc cagtatctgt gaaatgatgt tttatctgtg     5760

tgtcaggatg agaaacggca gtcattccac caagtgttgg aaactggtta gcctggagac     5820

aagggtttct ggggccacag ctcagggatg tgtatttaat tacaggatcc ccagaaactc     5880

ctctctaggc tgccacagca acattttttc tgggcttggg agccatacct gaactgtttc     5940

ctccaaggcg ggaactccag agagcctgcc aagtctggag caagctgggg cttctgcttt     6000

ggccagacct gggccaccat gagacttgaa ggcttctagc tgtcctacga cacgagccac     6060

ggtggccctg cctctccccg ctcatagaag cctggtccct ctgtctagcc cagttcccat     6120

ctagcatccg tcttctgggc ctgaagccct aaatggacca cagcctgcac aggaatcaac     6180

tgtaggctca aagggaggcg gtgagtaagg tcagagcctg ctccaagccc aagaacaaaa     6240

gttgtgttat gggtggaggc tagtccccca gatctagccc tgccgtcttt gccctttaat     6300

gaccattgtt ttctttctct aaaatgtctt gtaataggtg ataatgttgt tgattcaaat     6360

ttccatgaaa aagaaaaaaa aaactacctc ttaagcgaca tcctggtcga ttcctctctg     6420

aggaatcctg tgggaaaaga atactgtagc tcctgctctg tttacatgtt tctgtcggga     6480

aagaagcccc gcctgccctg gggtgttggt gtttttgtct gtgttgccat cccaggtctg     6540

ccataggggc tggtggctgc attgtgatgt ctgggctgtg tctggggatt ccttcccacc     6600

tacccagcca gggactagtc acccccctga agaggcctcc atttccttcc tgtgctccag     6660

ggcataggga gcaccactcc cacagacacc acctttaagg gctctagtgg cacacacatc     6720

cacgagccta cccccaggtt acctgcccta ggtccacctc cacccacagt cctgtgtgta     6780

ggaatcgagg aaacgggatg tccctgagcc cttgtctcca aagggccggc caagggctgc     6840

ccgccagcct gactccatca accctccatg accaaatgat agctggcggg ctctgcaggc     6900

tacccaggcc ctctgctacc tcccaccctg ccagctggca agggatgggc cctgttctgt     6960

gaattgacta cctgtggaaa tgtgaccaat tagtgtgaaa tgcatgttta gcaagtgtta     7020

ggtactgtat ttgaaccaat aaatgtgaat ccttctgcac atgg                      7064


<210>  534
<211>  2251
<212>  DNA
<213>  homo sapiens

<400>  534
gaccattagc aggcacccag gcctgtcttt ggctcggaaa cggtggcccc caatgtagcc       60

tagtttgaac ctaggaactg caggaccaga gagattccac tggagcctga tggacgggtg      120

acagagggaa ccctactctg gaaactgtca gtcccagggc actggggagg gctgaggccg      180

accatgccca gcctgctgct gctgttcacg gctgctctgc tgtccagctg ggctcagctt      240

ctgacagacg ccaactcctg gtggtcatta gctttgaacc cggtgcagag acccgagatg      300

tttatcatcg gtgcccagcc cgtgtgcagt cagcttcccg ggctctcccc tggccagagg      360

aagctgtgcc aattgtacca ggagcacatg gcctacatag gggagggagc caagactggc      420

atcaaggaat gccagcacca gttccggcag cggcggtgga attgcagcac agcggacaac      480

gcatctgtct ttgggagagt catgcagata ggcagccgag agaccgcctt cacccacgcg      540

gtgagcgccg cgggcgtggt caacgccatc agccgggcct gccgcgaggg cgagctctcc      600

acctgcggct gcagccggac ggcgcggccc aaggacctgc cccgggactg gctgtggggc      660

ggctgtgggg acaacgtgga gtacggctac cgcttcgcca aggagtttgt ggatgcccgg      720

gagcgagaga agaactttgc caaaggatca gaggagcagg gccgggtgct catgaacctg      780

caaaacaacg aggccggtcg cagggctgtg tataagatgg cagacgtagc ctgcaaatgc      840

cacggcgtct cggggtcctg cagcctcaag acctgctggc tgcagctggc cgagttccgc      900

aaggtcgggg accggctgaa ggagaagtac gacagcgcgg ccgccatgcg cgtcacccgc      960

aagggccggc tggagctggt caacagccgc ttcacccagc ccaccccgga ggacctggtc     1020

tatgtggacc ccagccccga ctactgcctg cgcaacgaga gcacgggctc cctgggcacg     1080

cagggccgcc tctgcaacaa gacctcggag ggcatggatg gctgtgagct catgtgctgc     1140

gggcgtggct acaaccagtt caagagcgtg caggtggagc gctgccactg caagttccac     1200

tggtgctgct tcgtcaggtg taagaagtgc acggagatcg tggaccagta catctgtaaa     1260

tagcccggag ggcctgctcc cggcccccct gcactctgcc tcacaaaggt ctatattata     1320

taaatctata taaatctatt ttatatttgt ataagtaaat gggtgggtgc tatacaatgg     1380

aaagatgaaa atggaaagga agagcttatt taagagacgc tggagatctc tgaggagtgg     1440

actttgctgg ttctctcctc ttggtgggtg ggagacaggg ctttttctct ccctctggcg     1500

aggactctca ggatgtaggg acttggaaat atttactgtc tgtccaccac ggcctggagg     1560

agggaggttg tggttggatg gaggagatga tcttgtctgg aagtctagag tctttgttgg     1620

ttagaggact gcctgtgatc ctggccacta ggccaagagg ccctatgaag gtggcgggaa     1680

ctcagcttca acctcgatgt cttcagggtc ttgtccagaa tgtagatggg ttccgtaaga     1740

ggcctggtgc tctcttactc tttcatccac gtgcacttgt gcggcatctg cagtttacag     1800

gaacggctcc ttccctaaaa tgagaagtcc aaggtcatct ctggcccagt gaccacagag     1860

agatctgcac ctcccggact tcaggcctgc ctttccagcg agaattcttc atcctccacg     1920

gttcactagc tcctacctga agaggaaagg gggccatttg acctgacatg tcaggaaagc     1980

cctaaactga atgtttgcgc ctgggctgca gaagccaggg tgcatgacca ggctgcgtgg     2040

acgttatact gtcttccccc acccccgggg aggggaagct tgagctgctg ctgtcactcc     2100

tccaccgagg gaggcctcac aaaccacagg acgctgcaac gggtcaggct ggcgggcccg     2160

gcgtgctcat catctctgcc ccaggtgtac ggtttctctc tgacattaaa tgcccttcat     2220

ggaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                                    2251


<210>  535
<211>  2731
<212>  DNA
<213>  homo sapiens

<400>  535
gcactgcctc tggcacctgg ggcagccgcg cccgcggagt tttccgcccg gcgctgacgg       60

ctgctgcgcc cgcggctccc cagtgccccg agtgccccgc gggccccgcg agcgggagtg      120

ggacccagcc cctaggcaga acccaggcgc cgcgcccggg acgcccgcgg agagagccac      180

tcccgcccac gtcccatttc gcccctcgcg tccggagtcc ccgtggccag ggattattgg      240

acctgcctgg tttaaactat tgtcttagtt aattttgtgc tgctctaaca aaatatcaca      300

gactgagtaa tttataagca atagtagctt atttggctca cagttctgga ggctgagaag      360

atcgtgaggc tgcatctggc aagggccttc ttgctgcttc ataacatggc agaagacatc      420

atgcgggtgt gtgtctgggg aagagactta cagaagtgga gttgctgagt caaagatcta      480

accatgagct accctggcta tcccccgccc ccaggtggct acccaccagc tgcaccaggt      540

ggtggtccct ggggaggtgc tgcctaccct cctccgccca gcatgccccc catcgggctg      600

gataacgtgg ccacctatgc ggggcagttc aaccaggact atctctcggg aatggcggcc      660

aacatgtctg ggacatttgg aggagccaac atgcccaacc tgtaccctgg ggcccctggg      720

gctggctacc caccagtgcc ccctggcggc tttgggcagc ccccctctgc ccagcagcct      780

gttcctccct atgggatgta tccaccccca ggaggaaacc caccctccag gatgccctca      840

tatccgccat acccaggggc ccctgtgccg ggccagccca tgccaccccc cggacagcag      900

cccccagggg cctaccctgg gcagccacca gtgacctacc ctggtcagcc tccagtgcca      960

ctccctgggc agcagcagcc agtgccgagc tacccaggat acccggggtc tgggactgtc     1020

acccccgctg tgcccccaac ccagtttgga agccgaggca ccatcactga tgctcccggc     1080

tttgaccccc tgcgagatgc cgaggtcctg cggaaggcca tgaaaggctt cgggacggat     1140

gagcaggcca tcattgactg cctggggagt cgctccaaca agcagcggca gcagatccta     1200

ctttccttca agacggctta cggcaaggat ttgatcaaag atctgaaatc tgaactgtca     1260

ggaaactttg agaagacaat cttggctctg atgaagaccc cagtcctctt tgacatttat     1320

gagataaagg aagccatcaa gggggttggc actgatgaag cctgcctgat tgagatcctc     1380

gcttcccgca gcaatgagca catccgagaa ttaaacagag cctacaaagc agaattcaaa     1440

aagaccctgg aagaggccat tcgaagcgac acatcagggc acttccagcg gctcctcatc     1500

tctctctctc agggaaaccg tgatgaaagc acaaacgtgg acatgtcact cgcccagaga     1560

gatgcccagg agctgtatgc ggccggggag aaccgcctgg gaacagacga gtccaagttc     1620

aatgcggttc tgtgctcccg gagccgggcc cacctggtag cagttttcaa tgagtaccag     1680

agaatgacag gccgggacat tgagaagagc atctgccggg agatgtccgg ggacctggag     1740

gagggcatgc tggccgtggt gaaatgtctc aagaataccc cagccttctt tgcggagagg     1800

ctcaacaagg ccatgagggg ggcaggaaca aaggaccgga ccctgattcg catcatggtg     1860

tctcgcagcg agaccgacct cctggacatc agatcagagt ataagcggat gtacggcaag     1920

tcgctgtacc acgacatctc gggagatact tcaggggatt accggaagat tctgctgaag     1980

atctgtggtg gcaatgactg aacagtgact ggtggctcac ttctgcccac ctgccggcaa     2040

caccagtgcc aggaaaaggc caaaagaatg tctgtttcta acaaatccac aaatagcccc     2100

gagattcacc gtcctagagc ttaggcctgt cttccacccc tcctgacccg tatagtgtgc     2160

cacaggacct gggtcggtct agaactctct caggatgcct tttctacccc atccctcaca     2220

gcctcttgct gctaaaatag atgtttcatt tttctgactc atgcaatcat tcccctttgc     2280

ctgtggctaa gacttggctt catttcgtca tgtaattgta tatttttatt tggaggcata     2340

ttttcttttc ttacagtcat tgccagacag aggcatacaa gtctgtttgc tgcatacaca     2400

tttctggtga gggcgactgg gtgggtgaag caccgtgtcc tcgctgagga gagaaaggga     2460

ggcgtgcctg agaaggtagc ctgtgcatct ggtgagtgtg tcacgagctt tgttactgcc     2520

aaactcactc ctttttagaa aaaacaaaaa aaaagggcca gaaagtcatt ccttccatct     2580

tccttgcaga aaccacgaga acaaagccag ttccctgtca gtgacagggc ttcttgtaat     2640

ttgtggtatg tgccttaaac ctgaatgtct gtagccaaaa cttgtttcca cattaagagt     2700

cagccagctc tggaatggtc tggaaatgtc a                                    2731


<210>  536
<211>  2216
<212>  DNA
<213>  homo sapiens

<400>  536
atctctcagc gcagcaggac acggggacca tgcaagctgt aattggtcag gcatgaactc       60

tcttgggttg tgttaccctg tttgctgttt actgtcaaga tgctgaaaga atgttcttat      120

aatgatccaa gaggaagtgg caaatgagtg ctcttcttca ggatccaatg atagctggac      180

aagtcagtaa gcccttgctg tcagtgcgga gtgaaatgaa tgcggagttg agaggtgagg      240

acaaggctgc tacttcagac agcgagctga atgagcccct gcttgcgcct gtggaatcaa      300

atgacagcga ggacactccc agcaagctct tcggggctag aggaaaccca gcattatcag      360

acccaggcac tcctgaccaa caccaggcca gtcagaccca ccccccattt ccagttgggc      420

cacagccact tctgacggca cagcagttag cttctgctgt ggccggcgtg atgccgggag      480

gccccccagc cctcaaccag ccaatcctca ttcccttcaa catggcggga cagctaggag      540

gccagcaagg actggttctc acactgccaa cagcgaatct caccaacatc caagggctgg      600

tggcagcagc tgcagccgga ggcattatga ctctgccact gcaaaatcta caagctacct      660

catccctgaa ctcccagctc cagcagctcc agctccagct ccagcagcag cagcagcagc      720

agcagcagca gcctcccccg tcaaccaacc agcacccgca accagcccca caggcgccct      780

cgcagtccca gcagcagccg ctgcagccca ccccacccca gcagccacca cccgcctctc      840

agcagccgcc agctcctaca tctcagctgc aacaggcgcc tcagccccag cagcaccaac      900

cccactccca ctcccagaac cagaaccaac catctccaac ccagcagagc tccagccccc      960

cgcagaaacc tagtcagtct ccaggacatg gcctgccttc accgctcacg ccacccaatc     1020

ctctacagct ggttaataat ccactagcaa gtcaggctgc agcggctgca gcagccatga     1080

gctccatagc aagctcacag gcctttggca atgccctctc cagtcttcag ggggtcacag     1140

gtcaactagt tactaatgca caaggacaga ttatcgggac cattccactg atgcctaatc     1200

cagggccatc gagccaagca gcaagcggca ctcagggctt gcaagtgcag ccaatcaccc     1260

cccagctcct cacaaacgcc cagggccaga tcatcgccac agtcattggg aaccagatcc     1320

tgcccgtgat caacacccag ggcatcacgc tgtcacccat caagcccggc cagcagctcc     1380

accaaccctc ccagacgtca gtgggtcaag cagcctccca aggcaacctt ctgcacctgg     1440

ctcacagcca agcatccatg tctcaaagtc ccgtccggca ggcttcctct tcttcctcct     1500

catcctcctc ttcttcagct ttgagcgtgg gccagttagt cagcaatcct caaacggcag     1560

cgggtgaggt ggatggggtt aatctggagg agatccgaga atttgccaaa gcttttaaaa     1620

tccggcgcct gtcccttggc ctgacccaga ctcaggtggg acaggctctc agtgctacag     1680

agggccccgc gtacagccag tcggccatct gcaggtttga aaagctggac atcaccccta     1740

aaagtgccca gaagatcaag ccggtgcttg agcggtggat ggctgaggct gaggcccgcc     1800

atcgagcagg tatgcagaac ctgaccgagt ttatcgggag tgaaccatcc aaaaagcgca     1860

agcggcgcac ctccttcaca ccccaggccc ttgagatcct caatgcccac tttgagaaga     1920

acacacaccc ttctgggcag gaaatgaccg aaattgctga gaagctgaac tatgaccgag     1980

aagtagttag agtttggttc tgcaataaga ggcaagccct gaagaacaca attaaacgct     2040

taaaacagca cgagccggcc acggcagtcc ctttggagcc cttaacagac tctctggaag     2100

aaaactccta aagagatgcc cacccataat cagaagcaaa attcacagaa actaaactcc     2160

acccttggga ctccacaaca acaacaacaa caaaatttaa tttaatttaa aaatag         2216


<210>  537
<211>  2118
<212>  DNA
<213>  homo sapiens

<400>  537
tttttaagtt agtgctggaa cgtggaagag ctgctgcctc cgaagcagta aaccagcccc       60

tctgtttgtt tgtttgcttt gcccttagtt ccactgctcc aaacccaccc accaaggact      120

ctgaacctgt ccaccccggg cgcatcaaga tcttccagct gggtaccccc gatttgggcc      180

gactttgcac ctccaaacaa ccttagcatg atgtcttatc ttaagcaacc gccttacgca      240

gtcaatgggc tgagtctgac cacttcgggt atggacttgc tgcacccctc cgtgggctac      300

ccggccaccc cccggaaaca gcgccgggag aggacgacgt tcactcgggc gcagctagat      360

gtgctggaag cactgtttgc caagacccgg tacccagaca tcttcatgcg agaggaggtg      420

gcactgaaaa tcaacttgcc cgagtcgagg gtgcaggtat ggtttaagaa tcgaagagct      480

aagtgccgcc aacaacagca acaacagcag aatggaggtc aaaacaaagt gagacctgcc      540

aaaaagaaga catctccagc tcgggaagtg agttcagaga gtggaacaag tggccaattc      600

actcccccct ctagcacctc agtcccgacc attgccagca gcagtgctcc tgtgtctatc      660

tggagcccag cttccatctc cccactgtca gatcccttgt ccacctcctc ttcctgcatg      720

cagaggtcct atcccatgac ctatactcag gcttcaggtt atagtcaagg atatgctggc      780

tcaacttcct actttggggg catggactgt ggatcatatt tgacccctat gcatcaccag      840

cttcccggac caggggccac actcagtccc atgggtacca atgcagtcac cagccatctc      900

aatcagtccc cagcttctct ttccacccag ggatatggag cttcaagctt gggttttaac      960

tcaaccactg attgcttgga ttataaggac caaactgcct cctggaagct taacttcaat     1020

gctgactgct tggattataa agatcagaca tcctcgtgga aattccaggt tttgtgaaga     1080

cctgtagaac ctctttttgt gggtgatttt taaatatact gggctggaca ttccagtttt     1140

agccaggcat tggttaaaag agttagatgg gatgatgctc agactcatct gatcaaagtt     1200

ccgagaggca tagaaggaaa aacgaagggc cttagagggg cctacaaacc agcaacatga     1260

aatggacaaa ccaatctgct taagatcctg tcatagtttt agatcattgg ttatcctgat     1320

ttgcaaagtg atcaaaagca ttctagccat gtgcaaccaa acaccaccaa aaataaaatc     1380

aaacaaaact aagttgtgaa ggaagggagg gaaggtcata gccttcttaa gcagaggtgt     1440

tccattgttt tagccaatcc ttggttgaat cttaggaatg aacagtgtct caagctcatt     1500

cacgtttcat gaccaactgg tagttggcac tgaaaaaact tttcagggct gtgtgaattg     1560

tgtgactgat tgtcctagat gcactacttt atttaaaaaa taatgttcat aaggagtcaa     1620

tatgtagttt aagagacaat cagtgtgtgt cttataaatg gtacatctgt ggtttttaat     1680

ctgtgctaga cttcaaaact gtgatctcct gttattgtat gcaaccttga actccacctc     1740

tgcaggggtt cttctgtgat taaataggtt ataattataa gcaaaattca gagcaactga     1800

gtactgatct aaaaagatta cctttggctg gaggtgagct gcactgaaac tttacgacaa     1860

aatgtctctg gacaaagaga gtcagagaag agaagcaaaa ggacactaat tcatctgtaa     1920

tttactgttg gtaagcctag cagtaaagag acattggtca attgctctga ccctgatgaa     1980

ttattaaact gagatcattg tcgtttatgc ttgcagatgt taaatggaaa agttatatat     2040

gcataaacct tttcttcctg gatttggcag atatgtataa ttatattaaa atggttctag     2100

cacaaaaaaa aaaaaaaa                                                   2118


<210>  538
<211>  10759
<212>  DNA
<213>  homo sapiens

<400>  538
attctccgcg gcgcggcggc gagtgctggc tgcggtaccc tcccgctcgc ttgtccgtct       60

gcgcgcccgc gatgtgacca gccgactggg ggcgggctgg cggctctgcc tgcggcagcg      120

catcggtttt tctcctggca ggtccctaat tgagccgtga ttcccttgga gccagagaca      180

cccaccaggg gctcggagcg ccgcgctccg gggctggagg cagctgcagc gctcgggtcc      240

gcgcggccgg gtgcagtagc ctcagtccca gccgccgcct cgctgagtcg tgtgccctgg      300

cgaatgcccg gcgcccggca cagctgagcc aaggcgactg gtgcagagcg gcggcgcctg      360

gtcctgcact tgccgctgct gccgggctgt gccggggcgg cggcgctgcg cgccggagtt      420

tgcagaggct gcctccgagc gccgtccgcc aggaagactc cctgcctcct gagtcccaaa      480

aacacgagat ttttctccta tttcagcagt tggccacaac ttcattgctg ggaaaaggcc      540

aagaaagaag agagaactct caccacaaca tttcaaaggg aatacattgc cagaacttgg      600

aatactctac tggacaaaca tttcctccaa ggacacagct ctctgcctcc atgtcaccac      660

ctttgaagga ctgactgatt ccctcggctg gtgccagtgc ctgctcctgc catggggccc      720

gcggggagcc tgctgggcag cggacagatg cagatcaccc tgtggggaag tctggctgct      780

gtcgccattt tcttcgtcat caccttcctc atcttcctgt gctctagttg tgacagggaa      840

aagaagccgc gacagcatag tggggaccat gagaacctga tgaacgtgcc ttcagacaag      900

gagatgttca gccgttcagt tactagcctg gcaacagatg ctcctgccag cagtgagcag      960

aatggggcac tcaccaatgg ggacattctt tcagaggaca gtactctgac ctgcatgcag     1020

cattacgagg aagtccagac atcggcctcg gatctgctgg attcccagga cagcacaggg     1080

aaaccaaaat gtcatcagag tcgggagctg cccagaatcc ctcccgagag cgcagtggat     1140

accatgctca cggcgagaag tgtggacggg gaccaggggc tggggatgga agggccctat     1200

gaagtgctca aggacagctc ctcccaagaa aacatggtgg aggactgctt gtatgaaact     1260

gtgaaagaga tcaaggaggt ggctgcagct gcacacctgg agaaaggcca cagtggcaag     1320

gcaaaatcta cttctgcctc gaaagagctc ccagggcccc agactgaagg caaagctgag     1380

tttgctgaat atgcctcggt ggacagaaac aaaaaatgtc gtcaaagtgt taatgtagag     1440

agtatccttg gaaattcatg tgatccagaa gaggaggccc caccacctgt ccctgttaag     1500

cttctggacg agaatgaaaa ccttcaggag aaggaagggg gagaggcgga agagagtgcc     1560

acagacacga ccagtgaaac taacaagaga tttagctcat tgtcatacaa gtctcgggaa     1620

gaagacccca ctctcacaga agaagagatc tcagctatgt actcatcagt aaataaacct     1680

ggacagttag tgaataaatc ggggcagtcg cttacagttc cggagtccac ctacacctcc     1740

attcaagggg acccacagag gtcaccctcc tcctgtaatg atctctatgc tactgttaaa     1800

gacttcgaaa aaactccaaa cagcacactt ccaccagcag ggaggcccag cgaggagcca     1860

gagcctgatt atgaagcgat acagactctc aacagagagg aagaaaaggc caccctgggg     1920

accaatggcc accacggtct cgtcccaaag gagaacgact acgagagcat aagtgacttg     1980

cagcaaggca gagatattac caggctctag caacccagaa gacaaccctg ggtagcctgt     2040

gatcagtgtc tggagacgtt tcttctgtgg aagagaagaa gtgacacaaa cctatacttc     2100

atatgctgct ttagtcacct gaagatggtt ggagaggccc tgtcgactgt tctcccagtt     2160

gttcagtttc tgagacagag aggtacggac taggctgcac ctgagtgtgc ccctgcctgc     2220

cagatggaca ggtacaccca agcacatctc cctgctgcac cctcaccacc cacaaaagat     2280

cccagctgtc agtggtctca tctcattagt gaggaaagcc aagctgtatg gaaaagctgc     2340

actcaccaag gaccacaatg cccccggcct aaagtactgc cattcagaaa agcaggtttt     2400

tcttcctctc tttccttttc tctgtctgct actgacttta aggctttttc ccccttgaaa     2460

tgtccagatt cctgtggttc atcccaagga aattttcaca caaagcttgg cctttgccct     2520

caatataggt gttttaggat ggtgacaaac catggctgct gctttctgcc cagctcgcca     2580

gtcctcccca aagagttgcg catcagcacc tggggatctg gaccctgcgg gtgaagggat     2640

ggggagggac gtccctggag tctcttctgt ctttgttcct tcttattttg gcattcgata     2700

tcagcagcct ctccccaaag tacttgaagt cagttttaga tgctttattt tatttttcta     2760

gtcaaaaacg tgtttccccc agtgtttgaa aactcgtccg aatcttttca gtattttcca     2820

tgagtattgt ggtacttcta gacttgttta agcccagaac tcattccttc aaaacagaga     2880

gccttaatct ttatgttggg acacagacca catatttgga cggcagccat gcatccatcg     2940

ctgaagggct gtggacatga atgtgtattt cccatggtct ccgctgccca caccaacagt     3000

gtggcatctc ataagttaac tgctacccta aggtaatcta agattaaaat gtaaacattt     3060

atttttgtta tgtaagttta taagatgttt tatgttcaat gcctaatttc tcaaaagtgc     3120

cagaaaaaaa tgtatattag ctattttgat tttatgtaca atgatttata ctctcctttt     3180

gaaaagatac cataaagcac ataagctaga tcactacaag gagctgttat cttttttcta     3240

atcaagtgtt taaaacactg atggttttta aagactcacc tttttaaatg gtacttggag     3300

ctcctgattc aaattaccta gaccccctag agaaataaat ggaatataca taaataatca     3360

ttttcagtgg tttatggtgg gcaatattgc aatatttgaa atggtaaaaa tggaaagaag     3420

aacaaaatat gatgagaggt ggctgtgaat tataaacctc ataaaagtgt cataattcca     3480

ttaaggttta attatatttt ttcagaaaac agtgatgaat tctgtagtcc agtgcttgcc     3540

aatgcaaatt gcctattgga atcttcttcc tatattttac aaacatcagt ggctgaaata     3600

gctcagagta agagctcagc ctggtttgaa tttaatcatc tctttagatc ttataaggcc     3660

agcattagga aacttgttca cttttcattt tcaaaggagc ctagttgaag tgctattatg     3720

agtgtgggct atggaaagac agcttttcct acactgataa agaaaaaaaa tgaggaaatt     3780

atttcatccc cttgtgacat ctgtgacttt ttggatttaa taatcttgct gtttttcctc     3840

tttatgacaa agaatataat tgggaggatg aagtgtctta aaaattgtag agaccagctc     3900

actggaatgt ttttccatcc ctgtattcat ggcttgactt tgtgactgct ctacactgca     3960

tgtctgacat tgcagagtga gctatgttga ggtaaactgg ttggttgtca ttattttgca     4020

atcagcctgg tctctcccat gaagatgtcg tgtgcataag cacaatcatc actgattaga     4080

agatcacagc agaataccct tggattagag agaagttcgt accttgcatt tctctgaatt     4140

ctagtctctc ataagcactg ctttgctgga tgattttcac tgctttgtgt taatgacttt     4200

gagcgatctc tcacatgatg gggttcttta gtacatggta acagccatgt catcttacac     4260

acctagcatt gtgaatgctg tagtgacatc ctttataggc accttacagc tcaaaacttt     4320

tgtttcattt catgccttac ttatcaaaaa ggcaggaaag taggtatgat ctctaaagta     4380

aaaaaaaaaa aaaaaaaaaa actttttata gaaagctcat aaataatcat gtcattttgc     4440

aattttgtta ccaaaatttc ccccaagagt tttcaaatat tagttctgca atgtggctat     4500

gaaatatgca ctgaaatata ccttttaatt tgagaaccag tggttagaat aagctgtgat     4560

ataaagtatt ttcagtgtac ttttaaagga actataaggc cctccagcat aaacgctaaa     4620

agaatagatg gtagcacagg ccatgagggc tgggggagag aagcagagtg aaccttagaa     4680

agatggctca gctatttgga gcactggata ttttactgaa gttatttact gaggcaccat     4740

cactgttttg actgtacagt atagtttttc ataaatttca tcacatttac tttgttcaga     4800

atctgggctt gaatctttga gttggacaaa agcctatggt ttcttttaaa aagtttcatc     4860

ttgagctaat gctacagttt aaataaaatg tatgaaaggt agttatcaaa aacaatttgt     4920

atatttaaaa ttctattttg acatccattt tttacagcga attatagcag gttatgtgaa     4980

atttaaaaat aaattttagg aaattttttt atcttgtaag taagaattat aaatctatct     5040

cagttaaaag taggatcttt gtttttattc agatattttg aaagtttaga agcattttgt     5100

atgctacttt ggtatttctt aagtatagtc agcaggaaag ggtaacctgt tttatgcaaa     5160

atttttttaa tttgtcaaat gtttttagtg tgtctacttt ctgaaatagt ctcaatatcc     5220

tgtctgtatc ctaggcagat aactacacaa gaacaaaacg ctatatagaa aagaaaatat     5280

ttgaggaaat cttaaattcc ataagaaagt aattcttgca agaatgttgg ctacatattt     5340

ttttttctgt cctgaataaa ttacatcatt aggtctgttg aagcttttga agctaccact     5400

attctttctg ggataaaggc taattactga tttatctgcc ctcaaaatcc cagagttaat     5460

tctaattgag tactaaatta acagtaagta gttaacacag agaactaaaa tttaaccgca     5520

ttatatcact gtatatattt ctcatgattt ttgctaatta gagcatttac ttaaccagta     5580

ataaactaca cacacacaca cacacacaca cacgtatacg tgtgtgtgtg tatatacttg     5640

gctctgacac aactctggtg cttaattagg atatgttcta ttatgtattt tgaatgttta     5700

tcctgctagt gtgatgaact tttgttggaa aagcagaatt agaaggaaca gtttttcaat     5760

cagtttcatt tggtaattac aggaaaacct tgagttgctc taatttaatt tttccaatta     5820

atacatttag actttaaatt gcatccgtaa ttctcttggc tgaaaaacag tggtatttta     5880

agacagtttt gttatacatg tgacttactt ttgactcagc ctgagaggag gaaatgtaaa     5940

gagataagag atttggccca aagcagcaag agactagtaa ccttgagcca ggacgaagcc     6000

aagacaacgt gactcccaag tagcaggagc agaggtcggt cacctgtggc attctgtttc     6060

attccctttt aaaattatga gactttatag gcagtgtaaa acatcagcag gcagcgatgt     6120

gataggatgt gcgaaaaagc tggtctgata ccatggctat aattacagag ctttagttca     6180

attaggattt tgtaaatgag caaatgacct ttttttccag tgccccttgt aatagttaat     6240

atgagtccat gcaatcttgt gatgccattc tcctgaaggt gttgatttct ggtacccagc     6300

cagcttagct ttggctgctg gaagcacagt aggtactgat gattacttcc tggaaatctt     6360

gacaggctta ttgtactgtg taatggggaa aagttaaagt ataatgtttg gtgttaataa     6420

atgactgatg tgaaaatagg aacatgtgtc tttaatatca aatatggctt tatttgcagt     6480

gaaatctaaa ttccttattc tacagtagta ttttcttgcc ctgtgttgta tattttccta     6540

aatacatttt tcctgacagt ggctttaggc cagttgaaca cacttagact gaaagtgttt     6600

aacttaaaga gatcagtcca gaaaccatga taaattagaa tctttatctg gaattaccaa     6660

attaaaattt aaaatcatgg tccagaagag aacaaacatt catggttttt tttatcctac     6720

tgctcatttt taggtctgtg tttacatcta gtctctacta tttgtgaagt atgtcattat     6780

ttttttcaag ttcttctttg acttaactga aaaataatat tccaaattct taatgtaaca     6840

tgaaaagaga aatacaattt ttgcttaaaa gacatttttt aaaaagcgtt caattcagta     6900

atcatttctg ttaatacagg aagttttttt ggcttgccag ttatatactg tgggtatttt     6960

ttaaaatgtg ctacccttgg gttgtctcat atcaccttgc gtaatcatgt attacaaagg     7020

ttgataattg tcatttctca gatgtctgta tgttacattg gcagcagtaa aatgttttaa     7080

tgttgttacc ttttaaataa ttgtgttgta ttaacatgcc tcatattttc tggggaaact     7140

tgaaatatat ctaaacaaaa aaggtctgtt ataaatagga attggcattt cattgttaat     7200

gttttttcct cataaaaata gttacaccaa aagtgacata ttgtctatta catgggccca     7260

atcagtatta aagtactccc cttactcaaa aatattaaaa aataattcat gacacttagt     7320

agcattttca ttgattgttt caaaagatct tcataatggt caaattgtcc aattcacaaa     7380

agagtgagaa agttgttttc agtactggga atttttaaac cttagtttta agaccaaaaa     7440

tatctcttat tagcttgaac attttgtgat tacttttccc tccccggatc tagtcctttt     7500

aaggagtaag tctaaagaat gaggccatga agtcactatt tcctcccacc tcagtttgtc     7560

tcctggtact tagctggcct atcgctttgt gtggcaatac ccctgggtcg cttccccact     7620

cagccttctg tatctgctgt tcacaggaca tgccattatg tctttccagt acggatcaca     7680

gtgctgccat atcacagacc ctgccagccg gcacagaacc atgcctcgtc acagctctgc     7740

ccaactcaca ggctgccaag atgaggccac aggtccacct agggcggcag atgctggtgc     7800

tatttgtcac gacttttgcc aaaacatgta cactgttgct cacatctttc gtaagaatgg     7860

ttgacactaa ggggccatgg aaaagcactt ttaaaaaatt atgtggtgga atcaaactca     7920

cagaggcaga aatgttagtg ccgtgctcta accaagtaag cttagtgttc cccacagtga     7980

tctgtatctg gcctgagtct cctcaagcag caacccccac tgtccagcat gtggaaggta     8040

gatccttatg acaacaccag acccatagtt accaggaaag aaaaaggaag ctgagtgttg     8100

tgaaggggaa gaaatccttt ttataagaag taatcatttt taggccgggt gcagtggctc     8160

atgcctgtaa tcccagcact ttgggaggct gagacaggtg gatcacttga ggtcaggagt     8220

ttgagacctg cctggccaac atgatgaaac cctgtctcta ctaaaaatgc aaaaaaaatt     8280

agccaggcat ggtggcatgt gcctgtagtc ccaactactc aggaggctga ggcaggagaa     8340

tcacttgaac ctgggaggca gaggttgcaa tgagctgaga tcgcaacact gcactccagc     8400

ctgggcgaca gagcaagact ccatctcaaa aacaaaaaca aaaaaaaaac ctttttaaag     8460

taaattgagt gtaaaatgtt ttcaccatga agccattgca ccctctcccc caggaaacag     8520

tgcctaagga tgatgtcaag ttacagccag tttgctctga tcccccagga cctaagaaaa     8580

ctgtgagtgc ttcagcatgc aaaggtagag ctaccagata aggagaataa cttggccatt     8640

tatagcaaac tgcctgactt tggagtgaga aaccaagcac cttctaggtc ctaggatagg     8700

tgaattggag gtgcagctgc tgaagttccc attttctaca tacttcagga gccagggtgt     8760

ttcatttggt tttgtaaaac tttgctgtaa gtcatcacag ttaattcttt gaatggacat     8820

tttagagtgt aacttttttt caaaattagc agaacagata tctctgctca ttctctttat     8880

acatttagtt ttttaaagtt cccctagtat acctgttagg cactctaaat aggacacagt     8940

taaagctaaa agaaggacca gttgctccct agagcctaca gttcagaact atcttgttgt     9000

catgtcctgg tttggtttgg tttgttttta actcaacaag ttggaaacca tgagtttaaa     9060

gcaaactatt tccttttctt aagcttaaag agaatttttt ttttaatctt tagctcctca     9120

tttaggtagt gaaggcttcc ctgaaagaca gcagtgccct tctctggaag aagaggctgg     9180

gaccaaaagc ctgagtctat gggttgagga ttttgagcat tcctttgaca agcttctatg     9240

tatttttaat ataagactca taaatgaacc tgatgtggtg ttcatgaccc atcccttaag     9300

catgcttgct ttttttaact ttactttttg agtatagtac ttgtcttgtt tttcctggag     9360

ccatgctagg atttaattcc tatgtgccac tacccgccca tgtcctggaa gatggccatg     9420

cctgcagcaa tgctcatgtc ttgaggagaa gcaatgtgaa aagcatcagg aaagctgaac     9480

cttacgttca agtcagcaaa catttgtgag cattctagta tgcttgcgac cttgacactt     9540

tttaaaaatt atctttttat ttgcttcgag tatcaaccgt atagttgact ctagtggggc     9600

gaagggagca gagatgagag caaaattcag acttgctgcc cctgtgtgtc tcagttctca     9660

tgtctctctg agaaatgtgt tggcccaatt ccctatctgc cactctgagt ctcttgagta     9720

aatgtgtgta aatgagaaaa attatctcaa agatttaact tattatttag atattttctt     9780

ctttttaaac tcaggaataa acctggtttg tagataatat aatatggcta ctagagctat     9840

aattgagtag gtgactagaa gcattttttc aaatatattt cttgtaaaga catctacttt     9900

gttttaacta ggaaaagaaa ctcctcatat taaaataaac atttccataa gcactttcta     9960

gaagagtgta gcatccatct accatccatc ccagaatgtt tgtatcttgc tcatagtatt    10020

tcaaaaattt ttatgggtga aaaaaatgca cttttttatt tattggaaaa gtgtagagtt    10080

attgaattaa attctcaagt gggacaattt agtgtaaagg gaaacatggg ttttggagac    10140

aagagcacag ggctgtggtc cctgttccag cattgacttt actatgtgac ctcgagcaaa    10200

tgatttaact tctctgtgcc tcagtttctc catatacaaa atggggataa tgatactaac    10260

cattgcctac ctcatagaga tgttatgggg acaaacgaaa taatagagat aagcacgaat    10320

gctttcaact cttcggaaga aaggtgctat ataaattgaa gttgtgtttt taatgatcca    10380

attattaatt atgtttaggg tttaaataac aatactgtta gtcatgttaa gaataagttt    10440

tgttttgatg catatttcca cttctcttct gtggccagat cttgatcatt caaccagtaa    10500

tggtacctga ggaactgaaa tgggtatttg ttttcgtatg tttctgccag tagtatttca    10560

attgaatatc cagaaaagac tggagtttaa cttgtaatat cttatagttt acatgtaata    10620

aaacttattc aagctatata taaaagtatg attacatgta aatagcaggt atgttgtaat    10680

taaaggcact tatcaaattg tctttgttct tttttaattg taataaaagt cagttttaca    10740

taaaaaaaaa aaaaaaaaa                                                 10759


<210>  539
<211>  10759
<212>  DNA
<213>  homo sapiens

<400>  539
attctccgcg gcgcggcggc gagtgctggc tgcggtaccc tcccgctcgc ttgtccgtct       60

gcgcgcccgc gatgtgacca gccgactggg ggcgggctgg cggctctgcc tgcggcagcg      120

catcggtttt tctcctggca ggtccctaat tgagccgtga ttcccttgga gccagagaca      180

cccaccaggg gctcggagcg ccgcgctccg gggctggagg cagctgcagc gctcgggtcc      240

gcgcggccgg gtgcagtagc ctcagtccca gccgccgcct cgctgagtcg tgtgccctgg      300

cgaatgcccg gcgcccggca cagctgagcc aaggcgactg gtgcagagcg gcggcgcctg      360

gtcctgcact tgccgctgct gccgggctgt gccggggcgg cggcgctgcg cgccggagtt      420

tgcagaggct gcctccgagc gccgtccgcc aggaagactc cctgcctcct gagtcccaaa      480

aacacgagat ttttctccta tttcagcagt tggccacaac ttcattgctg ggaaaaggcc      540

aagaaagaag agagaactct caccacaaca tttcaaaggg aatacattgc cagaacttgg      600

aatactctac tggacaaaca tttcctccaa ggacacagct ctctgcctcc atgtcaccac      660

ctttgaagga ctgactgatt ccctcggctg gtgccagtgc ctgctcctgc catggggccc      720

gcggggagcc tgctgggcag cggacagatg cagatcaccc tgtggggaag tctggctgct      780

gtcgccattt tcttcgtcat caccttcctc atcttcctgt gctctagttg tgacagggaa      840

aagaagccgc gacagcatag tggggaccat gagaacctga tgaacgtgcc ttcagacaag      900

gagatgttca gccgttcagt tactagcctg gcaacagatg ctcctgccag cagtgagcag      960

aatggggcac tcaccaatgg ggacattctt tcagaggaca gtactctgac ctgcatgcag     1020

cattacgagg aagtccagac atcggcctcg gatctgctgg attcccagga cagcacaggg     1080

aaaccaaaat gtcatcagag tcgggagctg cccagaatcc ctcccgagag cgcagtggat     1140

accatgctca cggcgagaag tgtggacggg gaccaggggc tggggatgga agggccctat     1200

gaagtgctca aggacagctc ctcccaagaa aacatggtgg aggactgctt gtatgaaact     1260

gtgaaagaga tcaaggaggt ggctgcagct gcacacctgg agaaaggcca cagtggcaag     1320

gcaaaatcta cttctgcctc gaaagagctc ccagggcccc agactgaagg caaagctgag     1380

tttgctgaat atgcctcggt ggacagaaac aaaaaatgtc gtcaaagtgt taatgtagag     1440

agtatccttg gaaattcatg tgatccagaa gaggaggccc caccacctgt ccctgttaag     1500

cttctggacg agaatgaaaa ccttcaggag aaggaagggg gagaggcgga agagagtgcc     1560

acagacacga ccagtgaaac taacaagaga tttagctcat tgtcatacaa gtctcgggaa     1620

gaagacccca ctctcacaga agaagagatc tcagctatgt actcatcagt aaataaacct     1680

ggacagttag tgaataaatc ggggcagtcg cttacagttc cggagtccac ctacacctcc     1740

attcaagggg acccacagag gtcaccctcc tcctgtaatg atctctatgc tactgttaaa     1800

gacttcgaaa aaactccaaa cagcacactt ccaccagcag ggaggcccag cgaggagcca     1860

gagcctgatt atgaagcgat acagactctc aacagagagg aagaaaaggc caccctgggg     1920

accaatggcc accacggtct cgtcccaaag gagaacgact acgagagcat aagtgacttg     1980

cagcaaggca gagatattac caggctctag caacccagaa gacaaccctg ggtagcctgt     2040

gatcagtgtc tggagacgtt tcttctgtgg aagagaagaa gtgacacaaa cctatacttc     2100

atatgctgct ttagtcacct gaagatggtt ggagaggccc tgtcgactgt tctcccagtt     2160

gttcagtttc tgagacagag aggtacggac taggctgcac ctgagtgtgc ccctgcctgc     2220

cagatggaca ggtacaccca agcacatctc cctgctgcac cctcaccacc cacaaaagat     2280

cccagctgtc agtggtctca tctcattagt gaggaaagcc aagctgtatg gaaaagctgc     2340

actcaccaag gaccacaatg cccccggcct aaagtactgc cattcagaaa agcaggtttt     2400

tcttcctctc tttccttttc tctgtctgct actgacttta aggctttttc ccccttgaaa     2460

tgtccagatt cctgtggttc atcccaagga aattttcaca caaagcttgg cctttgccct     2520

caatataggt gttttaggat ggtgacaaac catggctgct gctttctgcc cagctcgcca     2580

gtcctcccca aagagttgcg catcagcacc tggggatctg gaccctgcgg gtgaagggat     2640

ggggagggac gtccctggag tctcttctgt ctttgttcct tcttattttg gcattcgata     2700

tcagcagcct ctccccaaag tacttgaagt cagttttaga tgctttattt tatttttcta     2760

gtcaaaaacg tgtttccccc agtgtttgaa aactcgtccg aatcttttca gtattttcca     2820

tgagtattgt ggtacttcta gacttgttta agcccagaac tcattccttc aaaacagaga     2880

gccttaatct ttatgttggg acacagacca catatttgga cggcagccat gcatccatcg     2940

ctgaagggct gtggacatga atgtgtattt cccatggtct ccgctgccca caccaacagt     3000

gtggcatctc ataagttaac tgctacccta aggtaatcta agattaaaat gtaaacattt     3060

atttttgtta tgtaagttta taagatgttt tatgttcaat gcctaatttc tcaaaagtgc     3120

cagaaaaaaa tgtatattag ctattttgat tttatgtaca atgatttata ctctcctttt     3180

gaaaagatac cataaagcac ataagctaga tcactacaag gagctgttat cttttttcta     3240

atcaagtgtt taaaacactg atggttttta aagactcacc tttttaaatg gtacttggag     3300

ctcctgattc aaattaccta gaccccctag agaaataaat ggaatataca taaataatca     3360

ttttcagtgg tttatggtgg gcaatattgc aatatttgaa atggtaaaaa tggaaagaag     3420

aacaaaatat gatgagaggt ggctgtgaat tataaacctc ataaaagtgt cataattcca     3480

ttaaggttta attatatttt ttcagaaaac agtgatgaat tctgtagtcc agtgcttgcc     3540

aatgcaaatt gcctattgga atcttcttcc tatattttac aaacatcagt ggctgaaata     3600

gctcagagta agagctcagc ctggtttgaa tttaatcatc tctttagatc ttataaggcc     3660

agcattagga aacttgttca cttttcattt tcaaaggagc ctagttgaag tgctattatg     3720

agtgtgggct atggaaagac agcttttcct acactgataa agaaaaaaaa tgaggaaatt     3780

atttcatccc cttgtgacat ctgtgacttt ttggatttaa taatcttgct gtttttcctc     3840

tttatgacaa agaatataat tgggaggatg aagtgtctta aaaattgtag agaccagctc     3900

actggaatgt ttttccatcc ctgtattcat ggcttgactt tgtgactgct ctacactgca     3960

tgtctgacat tgcagagtga gctatgttga ggtaaactgg ttggttgtca ttattttgca     4020

atcagcctgg tctctcccat gaagatgtcg tgtgcataag cacaatcatc actgattaga     4080

agatcacagc agaataccct tggattagag agaagttcgt accttgcatt tctctgaatt     4140

ctagtctctc ataagcactg ctttgctgga tgattttcac tgctttgtgt taatgacttt     4200

gagcgatctc tcacatgatg gggttcttta gtacatggta acagccatgt catcttacac     4260

acctagcatt gtgaatgctg tagtgacatc ctttataggc accttacagc tcaaaacttt     4320

tgtttcattt catgccttac ttatcaaaaa ggcaggaaag taggtatgat ctctaaagta     4380

aaaaaaaaaa aaaaaaaaaa actttttata gaaagctcat aaataatcat gtcattttgc     4440

aattttgtta ccaaaatttc ccccaagagt tttcaaatat tagttctgca atgtggctat     4500

gaaatatgca ctgaaatata ccttttaatt tgagaaccag tggttagaat aagctgtgat     4560

ataaagtatt ttcagtgtac ttttaaagga actataaggc cctccagcat aaacgctaaa     4620

agaatagatg gtagcacagg ccatgagggc tgggggagag aagcagagtg aaccttagaa     4680

agatggctca gctatttgga gcactggata ttttactgaa gttatttact gaggcaccat     4740

cactgttttg actgtacagt atagtttttc ataaatttca tcacatttac tttgttcaga     4800

atctgggctt gaatctttga gttggacaaa agcctatggt ttcttttaaa aagtttcatc     4860

ttgagctaat gctacagttt aaataaaatg tatgaaaggt agttatcaaa aacaatttgt     4920

atatttaaaa ttctattttg acatccattt tttacagcga attatagcag gttatgtgaa     4980

atttaaaaat aaattttagg aaattttttt atcttgtaag taagaattat aaatctatct     5040

cagttaaaag taggatcttt gtttttattc agatattttg aaagtttaga agcattttgt     5100

atgctacttt ggtatttctt aagtatagtc agcaggaaag ggtaacctgt tttatgcaaa     5160

atttttttaa tttgtcaaat gtttttagtg tgtctacttt ctgaaatagt ctcaatatcc     5220

tgtctgtatc ctaggcagat aactacacaa gaacaaaacg ctatatagaa aagaaaatat     5280

ttgaggaaat cttaaattcc ataagaaagt aattcttgca agaatgttgg ctacatattt     5340

ttttttctgt cctgaataaa ttacatcatt aggtctgttg aagcttttga agctaccact     5400

attctttctg ggataaaggc taattactga tttatctgcc ctcaaaatcc cagagttaat     5460

tctaattgag tactaaatta acagtaagta gttaacacag agaactaaaa tttaaccgca     5520

ttatatcact gtatatattt ctcatgattt ttgctaatta gagcatttac ttaaccagta     5580

ataaactaca cacacacaca cacacacaca cacgtatacg tgtgtgtgtg tatatacttg     5640

gctctgacac aactctggtg cttaattagg atatgttcta ttatgtattt tgaatgttta     5700

tcctgctagt gtgatgaact tttgttggaa aagcagaatt agaaggaaca gtttttcaat     5760

cagtttcatt tggtaattac aggaaaacct tgagttgctc taatttaatt tttccaatta     5820

atacatttag actttaaatt gcatccgtaa ttctcttggc tgaaaaacag tggtatttta     5880

agacagtttt gttatacatg tgacttactt ttgactcagc ctgagaggag gaaatgtaaa     5940

gagataagag atttggccca aagcagcaag agactagtaa ccttgagcca ggacgaagcc     6000

aagacaacgt gactcccaag tagcaggagc agaggtcggt cacctgtggc attctgtttc     6060

attccctttt aaaattatga gactttatag gcagtgtaaa acatcagcag gcagcgatgt     6120

gataggatgt gcgaaaaagc tggtctgata ccatggctat aattacagag ctttagttca     6180

attaggattt tgtaaatgag caaatgacct ttttttccag tgccccttgt aatagttaat     6240

atgagtccat gcaatcttgt gatgccattc tcctgaaggt gttgatttct ggtacccagc     6300

cagcttagct ttggctgctg gaagcacagt aggtactgat gattacttcc tggaaatctt     6360

gacaggctta ttgtactgtg taatggggaa aagttaaagt ataatgtttg gtgttaataa     6420

atgactgatg tgaaaatagg aacatgtgtc tttaatatca aatatggctt tatttgcagt     6480

gaaatctaaa ttccttattc tacagtagta ttttcttgcc ctgtgttgta tattttccta     6540

aatacatttt tcctgacagt ggctttaggc cagttgaaca cacttagact gaaagtgttt     6600

aacttaaaga gatcagtcca gaaaccatga taaattagaa tctttatctg gaattaccaa     6660

attaaaattt aaaatcatgg tccagaagag aacaaacatt catggttttt tttatcctac     6720

tgctcatttt taggtctgtg tttacatcta gtctctacta tttgtgaagt atgtcattat     6780

ttttttcaag ttcttctttg acttaactga aaaataatat tccaaattct taatgtaaca     6840

tgaaaagaga aatacaattt ttgcttaaaa gacatttttt aaaaagcgtt caattcagta     6900

atcatttctg ttaatacagg aagttttttt ggcttgccag ttatatactg tgggtatttt     6960

ttaaaatgtg ctacccttgg gttgtctcat atcaccttgc gtaatcatgt attacaaagg     7020

ttgataattg tcatttctca gatgtctgta tgttacattg gcagcagtaa aatgttttaa     7080

tgttgttacc ttttaaataa ttgtgttgta ttaacatgcc tcatattttc tggggaaact     7140

tgaaatatat ctaaacaaaa aaggtctgtt ataaatagga attggcattt cattgttaat     7200

gttttttcct cataaaaata gttacaccaa aagtgacata ttgtctatta catgggccca     7260

atcagtatta aagtactccc cttactcaaa aatattaaaa aataattcat gacacttagt     7320

agcattttca ttgattgttt caaaagatct tcataatggt caaattgtcc aattcacaaa     7380

agagtgagaa agttgttttc agtactggga atttttaaac cttagtttta agaccaaaaa     7440

tatctcttat tagcttgaac attttgtgat tacttttccc tccccggatc tagtcctttt     7500

aaggagtaag tctaaagaat gaggccatga agtcactatt tcctcccacc tcagtttgtc     7560

tcctggtact tagctggcct atcgctttgt gtggcaatac ccctgggtcg cttccccact     7620

cagccttctg tatctgctgt tcacaggaca tgccattatg tctttccagt acggatcaca     7680

gtgctgccat atcacagacc ctgccagccg gcacagaacc atgcctcgtc acagctctgc     7740

ccaactcaca ggctgccaag atgaggccac aggtccacct agggcggcag atgctggtgc     7800

tatttgtcac gacttttgcc aaaacatgta cactgttgct cacatctttc gtaagaatgg     7860

ttgacactaa ggggccatgg aaaagcactt ttaaaaaatt atgtggtgga atcaaactca     7920

cagaggcaga aatgttagtg ccgtgctcta accaagtaag cttagtgttc cccacagtga     7980

tctgtatctg gcctgagtct cctcaagcag caacccccac tgtccagcat gtggaaggta     8040

gatccttatg acaacaccag acccatagtt accaggaaag aaaaaggaag ctgagtgttg     8100

tgaaggggaa gaaatccttt ttataagaag taatcatttt taggccgggt gcagtggctc     8160

atgcctgtaa tcccagcact ttgggaggct gagacaggtg gatcacttga ggtcaggagt     8220

ttgagacctg cctggccaac atgatgaaac cctgtctcta ctaaaaatgc aaaaaaaatt     8280

agccaggcat ggtggcatgt gcctgtagtc ccaactactc aggaggctga ggcaggagaa     8340

tcacttgaac ctgggaggca gaggttgcaa tgagctgaga tcgcaacact gcactccagc     8400

ctgggcgaca gagcaagact ccatctcaaa aacaaaaaca aaaaaaaaac ctttttaaag     8460

taaattgagt gtaaaatgtt ttcaccatga agccattgca ccctctcccc caggaaacag     8520

tgcctaagga tgatgtcaag ttacagccag tttgctctga tcccccagga cctaagaaaa     8580

ctgtgagtgc ttcagcatgc aaaggtagag ctaccagata aggagaataa cttggccatt     8640

tatagcaaac tgcctgactt tggagtgaga aaccaagcac cttctaggtc ctaggatagg     8700

tgaattggag gtgcagctgc tgaagttccc attttctaca tacttcagga gccagggtgt     8760

ttcatttggt tttgtaaaac tttgctgtaa gtcatcacag ttaattcttt gaatggacat     8820

tttagagtgt aacttttttt caaaattagc agaacagata tctctgctca ttctctttat     8880

acatttagtt ttttaaagtt cccctagtat acctgttagg cactctaaat aggacacagt     8940

taaagctaaa agaaggacca gttgctccct agagcctaca gttcagaact atcttgttgt     9000

catgtcctgg tttggtttgg tttgttttta actcaacaag ttggaaacca tgagtttaaa     9060

gcaaactatt tccttttctt aagcttaaag agaatttttt ttttaatctt tagctcctca     9120

tttaggtagt gaaggcttcc ctgaaagaca gcagtgccct tctctggaag aagaggctgg     9180

gaccaaaagc ctgagtctat gggttgagga ttttgagcat tcctttgaca agcttctatg     9240

tatttttaat ataagactca taaatgaacc tgatgtggtg ttcatgaccc atcccttaag     9300

catgcttgct ttttttaact ttactttttg agtatagtac ttgtcttgtt tttcctggag     9360

ccatgctagg atttaattcc tatgtgccac tacccgccca tgtcctggaa gatggccatg     9420

cctgcagcaa tgctcatgtc ttgaggagaa gcaatgtgaa aagcatcagg aaagctgaac     9480

cttacgttca agtcagcaaa catttgtgag cattctagta tgcttgcgac cttgacactt     9540

tttaaaaatt atctttttat ttgcttcgag tatcaaccgt atagttgact ctagtggggc     9600

gaagggagca gagatgagag caaaattcag acttgctgcc cctgtgtgtc tcagttctca     9660

tgtctctctg agaaatgtgt tggcccaatt ccctatctgc cactctgagt ctcttgagta     9720

aatgtgtgta aatgagaaaa attatctcaa agatttaact tattatttag atattttctt     9780

ctttttaaac tcaggaataa acctggtttg tagataatat aatatggcta ctagagctat     9840

aattgagtag gtgactagaa gcattttttc aaatatattt cttgtaaaga catctacttt     9900

gttttaacta ggaaaagaaa ctcctcatat taaaataaac atttccataa gcactttcta     9960

gaagagtgta gcatccatct accatccatc ccagaatgtt tgtatcttgc tcatagtatt    10020

tcaaaaattt ttatgggtga aaaaaatgca cttttttatt tattggaaaa gtgtagagtt    10080

attgaattaa attctcaagt gggacaattt agtgtaaagg gaaacatggg ttttggagac    10140

aagagcacag ggctgtggtc cctgttccag cattgacttt actatgtgac ctcgagcaaa    10200

tgatttaact tctctgtgcc tcagtttctc catatacaaa atggggataa tgatactaac    10260

cattgcctac ctcatagaga tgttatgggg acaaacgaaa taatagagat aagcacgaat    10320

gctttcaact cttcggaaga aaggtgctat ataaattgaa gttgtgtttt taatgatcca    10380

attattaatt atgtttaggg tttaaataac aatactgtta gtcatgttaa gaataagttt    10440

tgttttgatg catatttcca cttctcttct gtggccagat cttgatcatt caaccagtaa    10500

tggtacctga ggaactgaaa tgggtatttg ttttcgtatg tttctgccag tagtatttca    10560

attgaatatc cagaaaagac tggagtttaa cttgtaatat cttatagttt acatgtaata    10620

aaacttattc aagctatata taaaagtatg attacatgta aatagcaggt atgttgtaat    10680

taaaggcact tatcaaattg tctttgttct tttttaattg taataaaagt cagttttaca    10740

taaaaaaaaa aaaaaaaaa                                                 10759


<210>  540
<211>  5225
<212>  DNA
<213>  homo sapiens

<400>  540
gcctttggct tcagcgcttc gcccccgcgc tgtgccctct gtcggcggcg tggggcagct       60

gtagcagcgt tggcggcagg aggcggcggc cgcgtcgacg tcgacccaga ctggagcgac      120

gtttaaagaa ggggcagaat cgctggggag tgcggcttct tcttgttggg ggactcccag      180

ccttccgcgc gtccggagga ggagaagcgg cggcgccggg aagcaggcat ggagagtaga      240

aaactgattt ctgctacaga cattcagtac tctggcagtc tgctgaactc cttgaatgag      300

caacgtggcc atggactctt ctgtgatgtt accgttattg tggaagaccg aaaattccgg      360

gctcacaaga atattctttc agcttctagt acctacttcc atcagctctt ctctgttgct      420

gggcaagttg ttgaactgag ctttataaga gcagagatct ttgcagaaat tctcaattat      480

atctatagtt ctaaaattgt tcgtgttaga tcagatttgc ttgatgagtt aattaaatca      540

gggcagttat taggagtgaa atttatagca gagcttggtg tcccattgtc acaggttaaa      600

agcatctcag gtacagcgca ggatggtaat actgagcctt tacctcctga ttctggtgac      660

aagaaccttg taatacagaa atcaaaagat gaagcccaag ataatggggc tactataatg      720

cctattataa cagagtcttt ttcattatct gccgaagatt atgaaatgaa aaagatcatt      780

gttaccgatt ctgatgatga tgatgatgat gtcatttttt gctccgagat tctgcccaca      840

aaggagactt tgccgagtaa taacacagtg gcacaggtcc aatctaaccc aggccctgtt      900

gctatttcag atgttgcacc tagtgctagc aataactcgc cccctttaac aaatatcaca      960

cctactcaga aacttcctac tcctgtgaat caggcaactt tgagccaaac acaaggaagt     1020

gaaaaattgt tggtatcttc agctccaaca catctgactc ccaatattat tttgttaaat     1080

cagacaccac tttctacacc accaaatgtc agttcttcac ttccaaatca tatgccctct     1140

tcaatcaatt tacttgtgca gaatcagcag acaccaaaca gtgctatttt aacaggaaac     1200

aaggccaatg aagaggagga ggaggaaata atagatgatg atgatgacac tattagctcc     1260

agtcctgact cggccgtcag taatacatct ttggtcccac aggctgatac ctcccaaaat     1320

accagttttg atggatcatt aatacagaag atgcagattc ctacacttct tcaagaacca     1380

ctttccaatt ccttaaaaat ttcagatata attactagaa atactaatga tccaggcgta     1440

ggatcaaaac atctaatgga gggtcagaag atcattactt tagatacagc tactgaaatt     1500

gaaggcttat cgactggttg caaggtttat gcaaatatcg gtgaagatac ttatgatata     1560

gtgatccctg tcaaagatga ccctgatgaa ggggaggcca gacttgagaa tgaaatacca     1620

aaaacgtctg gcagcgagat ggcaaacaaa cgtatgaaag taaaacatga tgatcactat     1680

gagttaatag tagatggaag ggtctattat atctgtattg tatgcaaaag gtcatatgtc     1740

tgtctgacaa gcttgcggag acattttaac attcattctt gggagaagaa gtatccgtgc     1800

cgttactgtg agaaggtatt tcctcttgca gaatatcgca caaagcatga aattcatcac     1860

acaggggagc gaaggtatca gtgtttggcc tgtggcaaat ctttcatcaa ctatcagttt     1920

atgtcttcac atataaagtc agttcatagt caagatcctt ctggggactc aaagctttat     1980

cgtttacatc catgcaggtc tttacaaatc agacaatatg catatctttc cgatagatca     2040

agcactattc ctgcaatgaa ggatgatggt attgggtata aggttgacac tggaaaagaa     2100

cctccagtag ggaccactac atctactcag aacaagccaa tgacctggga agatattttt     2160

attcagcagg aaaatgattc aatttttaaa caaaatgtaa cagatggcag tactgagttt     2220

gaatttataa taccagagtc ttactaaact cctttgaaat actagaaagt tttgttttgg     2280

atgatggggc aggggtttca gaagatctgt aaaacaaatt aaggtgcgaa caagttaatt     2340

tgatctgcca cattatctga aggaagtgta gtgggatttt tgttgataat ttttagaagc     2400

aaattttcct gaaagttttg agtagaggtg agaccccctc cccaagtatc tgtttatata     2460

gttagttttc agctcattta aaagaggcaa aaattaaaag cttggagaga tagtttcctg     2520

aatagaattt gaagcagtct gaatgttctt tgaaaataac tggagttatt agcataccct     2580

agtacatctt acagctttcc ccttccatgt tagcacttta ctgctgaatt ctcaattttc     2640

ttaacattga gacaataaat gtgtgttttg tcttgtatat ggcataaaga gtaaataagt     2700

tttagagttg ttctggaaaa tgtcagaata agtcagtact tgggttgtgt aatctgctag     2760

tccaagcgaa cagcaacctc ctgctaccct ccctctatga aaatagccat gcagacaagt     2820

ctctcatctg aagaacaaat tagatttagc taattagaat taatcctggc tttcattgcc     2880

atagtctgta aaagactttg gtggctagac cactttatac cttcgcagtg tggtctctgg     2940

gggcaaaaaa ctaatgaaaa caatctctgt aatggcagat aggaggagat gaaaagttct     3000

gttgcatgga tttttaattc tctggctacc acatagtaga gaatggaatg aagatttcct     3060

tttggcttct taaggttaaa aatattccca tgaacatgaa aattttcaaa ttttgaatct     3120

gaaagccacc aaatgtatct ttatgtataa atccttgtaa atgatagatt ccatgggtga     3180

gactttacat attttgggtg ggaggctact ggcatatatt tttaaatgtt catattgcgt     3240

agaatctcca ctaggaagtc tttatttgaa atagttgaat cagtgatcta gtattttcct     3300

ttcggcaaga tttgttaggt ttttacccct tctaaaataa gttttattcc atctgcaaat     3360

tgctgcaata ttatagtaat cagaaactac ataaggaatg ttatataggc ttgtcagttc     3420

ccatttttct tgacaacaat aaataccact tttaaaaatg acacatattt aaacacttag     3480

aaaataaagt taacacttac tgaagtgcta gtactaaact gtgctagtac taaaagaaaa     3540

caggttggaa catacatata gcctagcatt tataacagaa ttgttgaacg tctgtaaatg     3600

attttttttt tttttgcaaa ggaaaaaatt gatactggaa aagattgttg tgcatagtta     3660

ttagtcattt gtaaccttgc ttaagtattt cttagtccaa catagatatt ttctttctcc     3720

tgaccatgta ttttaaaata tagtctattt cttgactttg aacttaaagc tttaatcata     3780

atttctcatg tatacatcgt tcttctgatg gtaagctgga tttgaaggta gtggtttcag     3840

tgtttcttaa gttggtagct gagggtatca ggcatcagtt catgcaataa tacaagaaaa     3900

aaaatccttt gcttgccaag aggtagagtg atgtgcattt atctgttttc tgttctgtaa     3960

gtctagacct tcaaaccatt tgtaaactaa cccctgggaa atttgaaatt acctgataac     4020

ttaagactct gtgatctctg gaatcaccat atgtttcttt tttgtgtaga tattaataac     4080

attactcttt gactatagtg tgcactctga aatgtactca gtgaaaattt gttttgagtt     4140

tcattaatgc tatttcacca gttagacata attacttcta ccgatgtgaa tgatacggat     4200

gccggcagag cttccagatc tttcagactc aactgctagg tcaattagtt tgtcataata     4260

aaacttggca gattctacaa gtctattatg acaaaccagg aactaattct ataatggaaa     4320

actatccatt ctgaataata ggtatgtaat tatttgctgc tgctgctgtg ctctgtaaat     4380

tctgaatatg acatttaaac tctgtgccta ctaaaggtat cttctggagt ttttgggagg     4440

agagaaactg gaaaattaaa ttgtattttt gccagaagac tcttacttgc atgtgtctca     4500

gggtcttcag tttttctata agtttccata tccaaagttc agaattcatg tgaaatactt     4560

ctttggggca aaagtccttc attcctggta tttattggat tggaaatctg tagcaagatg     4620

ctgtttaaaa ttaccatatt gtttttttat cttatactta gctctctggc tattgaactt     4680

ccttttcttg tttgaagtta gcttcaaatt tgctcctatg ctaaattacc tgtaaatatt     4740

ctggatagga actacttgaa atagtaattt gttaaaagat atgacaaaat gaaaatgctt     4800

aaactacaga aatttaaaaa tgccataaca atcttgcgag actaacttta aaatatactt     4860

taaatgatta ttatgatttt ggtggtaacg atcccccaca cacaaccact atgaagaaat     4920

aatgccgcat ttttccccca ttgtaccaaa aagataaaaa aatggtaaac actgatcaag     4980

gtattttgta ttgtcaaggc atgcatattc taaagaatta aatgctaact taacagcact     5040

ggctttctgg ctggtcaact atatgaaacc ttgttcattc ctccgagtac tgtaatgttc     5100

acacttgtac aatcttccct gtcatgactt taagttctac ttttcattaa ccatggcctg     5160

atattagttc ttagagcttc ttgtggcaaa aataaaatga tttaattcta aaaaaaaaaa     5220

aaaaa                                                                 5225


<210>  541
<211>  9351
<212>  DNA
<213>  homo sapiens

<400>  541
aaccgtcccc aacggtcgcc agcgcgcggc tcccgggccc cctcgctcct cccctctggc       60

ccctccgagc gctgggggtg cttccctccc cgcctcctcg cactcccact cgcgggcacg      120

ccggtggctg tgccgccatg ccccaccaca ggctgctcac gggcctaggc gcggcggccc      180

gagatagggg cccctgagcc tcccggggga ggagagaggc agcgagccgc gctccgcccc      240

ctccccccgg gccgccgccg ccgccgcctc gccgccccag cctggcggga gaaggaggag      300

gagcagcagg cctccgggcc cggcgccgcc gcccgcagga catttctgat ttatttgcat      360

ccttgaagag catctgtaga agaggaagta aaagatgggt gtgaaaacat ttactcatag      420

ctcctcttcc cacagccagg aaatgcttgg aaagctaaat atgctgcgaa atgatggaca      480

tttttgtgat atcactattc gtgtccagga caaaatcttc cgggcacata aggtggtact      540

agcagcttgc agtgatttct ttcgcaccaa acttgtaggc caagccgagg atgagaacaa      600

gaatgtgttg gatctgcatc atgttacagt gactggcttt atacctcttt tagaatatgc      660

ttacacagcc actctatcaa ttaacacaga aaatattatt gatgttctag cagcagccag      720

ctatatgcaa atgttcagtg ttgccagcac ctgctcagag ttcatgaaat caagcatttt      780

atggaataca cccaacagcc aacctgaaaa gggtctagat gctggacaag aaaataattc      840

taactgcaat tttacttctc gagatgggag catttctccc gtgtcctcag agtgcagtgt      900

ggtagaaaga accattcctg tctgccgaga atcccggaga aagcgcaaaa gctacattgt      960

tatgtctcct gaaagtcctg taaagtgtgg cacacaaaca agctcacccc aggtattgaa     1020

ttcttcagct tcctactcag aaaatagaaa ccaaccagtt gactcttcct tagcttttcc     1080

ttggactttt ccttttggaa ttgatcgaag gattcagcct gagaaagtta agcaagcaga     1140

aaatacccgg actttagaat tacctggccc atctgagacc ggtagaagaa tggctgatta     1200

tgtgacttgt gagagcacaa aaactacctt gcctttaggt accgaagaag atgtccgggt     1260

caaagtagaa agattaagtg atgaggaggt ccatgaggaa gtgtcccagc ctgtcagtgc     1320

atctcagagt tcgctgagtg atcagcagac agttccagga agtgaacaag tccaagagga     1380

ccttctgatt agtccacagt cttcctctat aggctcagta gatgaaggcg tttctgaggg     1440

cttgcctaca cttcaaagca cgtctagcac taatgctcct ccggatgatg atgatcgatt     1500

ggaaaatgtt cagtatccct accaactcta cattgctcct tccaccagca gtacagagcg     1560

accaagtcca aatggtcccg acagaccttt tcagtgtcca acctgcgggg tgcgattcac     1620

ccgtattcag aacctaaagc agcacatgct catccactca ggaattaaac catttcagtg     1680

tgaccgctgt gggaaaaagt tcaccagggc ttactcgcta aagatgcatc gcctaaagca     1740

tgaagtgatt tcctagtacc ggactactta aaccaggaac aagaagagac ccttgttcaa     1800

tatgatcttg gagaacacgg ttttgaaagc aactcctctg ttcaaatgcc tgtcatttca     1860

caggtctcct caacccagaa ttgtgaaagc acttttccct tggggtctct tggtgggctg     1920

gcagaaaaag aggaagaagt gccagagcag ccaaagagca gtgcttgtgc tgaggcaacc     1980

agagatgacc ccccaaaatc agagctgtct tctataacta ttgagtagtt ttgtgatttg     2040

gcttcagttt tgttttttgg aaagtgcctg tgcttggtct tgtacattta aatttaattt     2100

aattttttaa acaaaaaaag ccgggtggga gggaggggga gattgggaaa gaatttccct     2160

ttttactttc tgagccctga aactgatttt atttttccta actgagagat tgcttctgta     2220

agtacacaat aacatgatgt tgaaacagaa actatgagac ttaaggagaa ctggttgact     2280

taaaacatat accagttcct tcttccattg ttaaaagtag gctaacaaca gatcattagc     2340

tagagaggaa atcagatgat tattgacctt cttgagacaa gagggtacat gagaaactaa     2400

ttactaaaca gcttgacaaa tggcctgagt agatacttac tgctgtacac aggatgttgt     2460

ataatatttt gtaaagcctg ttgtttttgg aagtatttat ggtaagcttt cttaaaaatt     2520

attatggtaa atacttctga aatccggcgt acttttcttt aagctttgtc atttctgtta     2580

tgatttttca tggtgaaatt ttggtactga gatgggcatt ctctgtacct ttatagtacc     2640

actccaaagg caaggaacca tgattgacaa cagtcaagct gtggatgaaa tgaccaggaa     2700

cggagaatga agtatgtaaa tcccagcttc ataggaactc ttctcatact gcttttcaga     2760

ttaaaattgc tgtttacctg gtctccgaat gtaatgcctg actgtgtcat tgcccggatc     2820

agttttcccc ctgccccatc aatatgttct cttgcatata ttggcgtgct gccatataaa     2880

gtaaaaatac tggagatatt ctatatttta tatataggtt tatgtgttgt tggggatgtt     2940

ttcattgtgc tcttttggac ataataaata attctctatt gaggctacat tctttttttt     3000

tttctttttt tttaaaagaa tggcatctca ctctgttgcc caggctggag tatagtggct     3060

aagtcatagc tcactgcagc ttcgaactcc tgggctcagg ccattctcct gcctcagcct     3120

cttgagtatc taggattata ggcatgctcc accacacctg gttaacttca tttttatttt     3180

ttgtagagat gaggtctcac tatggtgccc aggctggtct tgaactccta gaccaagtga     3240

tcctcctcct ttggcctccc agactgctgg gatcactgca ccggccaagg ctgcattctt     3300

aacccaacta gattgtttac tgaatcccat atgacagcga tacattgtcc ttacatattt     3360

atttttagac attgcaaagt tattaaaaac agttaactat agtttttaca caacgtaggc     3420

aacaatgaag agtatagact gtaagatttt catctatgac tcataaatct gggagaaaaa     3480

aattattaag actaatgaga aactgaaaac cttaaactaa tgaatattat ttctgctgct     3540

aaaaatatga aactttctgg tctgtagttg aaatttgtat gatcctctag acttgggtat     3600

acttttcatc tggtgccatt aaagcatctc taatattgat cctaaatatt tgtaagtcca     3660

tgagcagtga actttggaat aagtttctgt gtagataccc aaagtttaat aattatgaga     3720

gcacctgatt tgatagacag aaaatacagt tctttagtca aaacacaaga tctgaatttt     3780

gttcaggtgc tagaccatac taaatgtata tatttttaat tatagtgatt tgtttcattt     3840

ttttagattg gctaattctg taattttttc cccaaaaaca tgtgaagaaa ggaaaagtaa     3900

attaaattcc ttagaactgt tttaggttaa gattctctgt gtctgcccat attctgcagt     3960

ccttaacttg ttttcaactc tttacctcac tcatgaactt gtttttaccc atttgctgcc     4020

aaacataggt gtgttccctt caggagaatc agcatataca ggttatgata ggctcccacc     4080

atttatgctt cttcactgat agggttgcat tactttctgc agcagactat aatacttcat     4140

atagtactgc tgtgtctcaa ctggaaaggt caggaatttt aatgttacgt tgtggtcttt     4200

gaaaactgtt aggcctagca atagataaat ctcaaaatta attttaaaat ctgtattgac     4260

aagaataggt aaaattatga ccaggaatca ttgttaccct tagttccaag aggtggtttt     4320

tgaaagagca agaggaaaga aaaaagaaaa gaaggaaaga agaataaaga agagaaacgt     4380

gtaagaatgg tttgcagatt gattggttaa aagtgttttt agcacatccc caaccctgaa     4440

aacttcgcat taagagccaa gcacaatgtt ggtagctcca agatattctg actgtgttct     4500

cagaatgagg gattacccat cactgggtat tccttcccaa gtagaaactt tagattttca     4560

ctggtaatac acattgccaa gttttatggg aaatctgaat atactgtgaa aatgcatatc     4620

tggttagttg tctgctgccc agatcttatc aataccagta actaaccagt atttaacata     4680

aaatgataca aataaaggcc tttttctatt tcagtgaggg tacatttttc ttgatatata     4740

tgtactttaa ggatattgga tctgtttatg gatctgtttt aggaaacaga tttgcaaggg     4800

ataattgtat atatagtagt atttaggttt atttcaaatt catcttaggg atgcctagat     4860

gcataatttt taccaggaca tattgaaaat attgcaaaga gatagccagt tatattatcc     4920

cattcattag aaattaccag tgtaactaaa cataaatatt ccagtttaga gtgcttaaac     4980

gtagctatct ttcttaaggc caggagggta actttgtggt atctaaaggg cttaaatttc     5040

agaatgcaga ataaattgcc tttttaaaac caagcatttt gtacaagctt ttattttcag     5100

ttttttaact accaaatagg tgtgatgtac tttagaagta aacaaagatg ttcacccatg     5160

ataatggatg ttaaagctcc tgcagttgtt cttttcgtgt ttaaagggta tattctaata     5220

gtggaagcat caaacatgtc agtgatttca tctcattcag aaataaagag attaatattg     5280

gtctttattt tttggcattt taagttttat ataaatggat gcagatggag attatcaccc     5340

acaaatatat ttaaatggat ttttcttaat ttgaatttca agtaatcttt ttatttcaag     5400

taattagtta cgcatttagt tacattgcca gttttttttt tttatcaatt tcagtaagac     5460

aaaatatact aaaatgttta aatagcctca ttcaatctta cattttgaca tttcagcaat     5520

cattctggct tacagtaatt agatcccctg ttacgacaca tgccctttgt tcttaataac     5580

tagcaaaaaa aaaaaaaaaa aaaaactttc atcttgttaa aatactttgc caaatgaaat     5640

agactagtca atacatctga tgtccataat tattggtaac tcagttacct tctaactaat     5700

aggctggttc aggagactct cccagtttat aaatggttct cttgggagcc tttggaagct     5760

gtattaaatc tttcagtctt ttatttctaa ttttttctct taatctaaat agaggccagt     5820

tatctatttt atcagctttt attcttgaag attctcagat tatgttttag tcccttttag     5880

ctttaatagt ccttgaaaaa tacattactg tataatgtgg caattctgta acagagactt     5940

attacttgaa tgaataatcc taaaatttta atattttagc tgaagtttga gatttgtgga     6000

atgaacaaaa gaattagaaa ctttcatatg ttactttgtt tcagtcatct gcaaagtatg     6060

aagctgtaat tctgaaatac acatccaagt gaatgagaat taaaaatttt ctaaatatta     6120

atactaactg ggaaaaaaaa actagtgtga agtttacagt tagaagaaac agacccaaag     6180

ttgccagaag gtaataaata aatgtagttt tcactgtaag taagttattg acgtaagatg     6240

ctttatttgt aatatattta gattttgaaa gttattgaga gatgaatgta taaaagctaa     6300

attttctttt ctgaagcagt gaaacaaaat tggggtaaca aggaagctct gttgtggcaa     6360

acatgtctat gaggaatatt aaaactaagc atactcccac aggctttaaa ctcaaactat     6420

gaacatttaa attaagttgt tccttatttt gcctataccc atttttatct ttcattgtcg     6480

tttttgcttg acagtatggt gacagagtat ttttatttgg aaagtcctca gcaagatgaa     6540

ttagccaaaa gcaataatgg ttcagattaa acaataaagt ggaattgatt caatcccagg     6600

ctcaactaag aacagtcgct ctctggatgt ttcattttag acgatagata agttgagatg     6660

ttgtaatatt tatggggggt taagcctgtg tcagttatgg gatgaagact tgtagtacca     6720

gtaccatcag tggtcatact tttttttaac tttttactaa actaatacag ttagacattt     6780

ccactctatc gtgattatat ttttatgatg ggaaaataaa aacacttcca tgtttttata     6840

aatagtctct gcaaagattt cagatgttat tggtatctcg gtttggcagt atctgaaaaa     6900

ttgagattgt ctttgaaatg tttgtgctac ttttacttaa gtaaaccccc actgtgcaag     6960

acccaggccg gcttcagcta ataccaaggt ttctgtgtgc ataatagttt acagagaact     7020

taagagtaag gactgcggat taaaaacaaa acttttttta actttaaaat ttttagtttt     7080

tgttcaaagt acctggttta taaagtcaaa ttcttttatt agttcctttc tcgtttaaat     7140

tgactgatgt tgctgatgaa gcttaaagtc ccaggcacgg ttgtggcgat atactgataa     7200

aattggtgcc tagtggtggg aggagctcca gtgtcaggac ttttattaaa aggcccttgt     7260

tttcccaaat gccaatctag ccacatttag atttcattat tcaataaaac agatgaaaaa     7320

tcatcccata aatgaatgtt gaggttacca aagtacatca cctgctgagg aaggataaat     7380

cttcctgctt taagggagcc ctgtcatctc tcctcttaat gcacgtttcc cttggtatta     7440

gtggaagctg tgttcaagat gggaagcctt tcctgcagtt cttagaaaca cctgctttct     7500

aaggagagcc ttttctagga ttagcttatg tgtgttttct ctaggcgatt ttttatttca     7560

gttaccaatt taattttcaa gttgacagat gctgtgtaaa gtctctcata atgagagtag     7620

tccattaaat tgttgaaagt tgcactgctt ttcatctttc aggtacctga aatgagtgac     7680

atcaggtatt tggaaggagt aagatcataa actgtattca ttttcttcct tgtacaaagt     7740

gatgacttct aatgcttata tctcaaggta ttttttaaaa aagcaacggt ccctaataga     7800

gtaaaatttg gttttggtcc aagttcccaa taatgtattt aatgtttctg ttgtttactg     7860

gtgcctcccg ttgcatcagg tagagattgc ctgcctcttt gtagggcagc cttgtggcac     7920

cttatgtcca acttggagga tagtatatgg cttctttgtg cctctactat cttttcaaaa     7980

gccattttat aaaaatccta ggtagcctat tttaatattt aaatatatat atttgtgaaa     8040

gaacttttag aacagacctt ttctttttac tttaaaattc ctgtatttcc atttttaaga     8100

gtaaatttaa tctccaggat ttagaagtgt ctttccagag aagcataatg agaaagtcag     8160

actgaggtaa taagaccaga attaagtgat agaagaaact gttgtttggt taaaggacac     8220

agatttgaag gaaaaaaatt ttgatgtaac aattttttaa ataaaatttt gtttttctgt     8280

aatgtcatat ttgctgctac agtagctcaa tattttacag ggctaacata aagctggctc     8340

catttaaaaa ctggagtact tcctagtgca gccagcctag gcggaaactg tacaccatgg     8400

tcttccagat gggtgactga tggctttggg tagctgatgc atgctttaat atttgcctat     8460

agcccggcag caaggaagtc ggggcggggg gactttttta ccctgccagt tatagcattg     8520

tgattctttc tgggcactgg cattttgtga aactctcaag ggaaggtgat gcaggggaga     8580

aaatgtgaat taaattacat agatgggtgt ttttatgtct tctacccctt tcctagaatt     8640

agtacaactc ttaactgtgc cagtccccag ttcaccagct ttgtatccag tcgtcatctc     8700

attcaagtat ggctttactt ggtgacactg gccatagcta agttaacttg gcatgtttga     8760

cttttgacaa taacaaaaat ggttttggat tttgttttat ttccaaaaaa tgtatacaat     8820

atcagaactt cacattttat atactagtat ctggctatta gtattttaca ggaaccatag     8880

ttcttggtga ctacatatat atatatattt ttgtgacctt ttttgtaaac taagtgccgt     8940

ttcaacgtta caatcatttt tagggttatt gtaatcaatg tgaatatcat gttttttcaa     9000

atctgttctg agcctatagt gtttgctttg tgaacatgtg tattgtatat attctgtata     9060

gttatattgt actgaaatta gcttgtttga tataaggaaa atatgtattg agtacctttt     9120

tgctagcctg attgtttaat ctttttaaaa aaggtttaaa ctttttttaa aaaaaaaatc     9180

tttaaactgg cctttattac atggtcacac ataaagttgc agttaggaaa gggatgggca     9240

gggaaaaact agttttgagt gtctttagat agaaacatga gactaaggtt tgattttgtt     9300

ttcgttttct cattaaaata tcttatgctt tatggaataa aaaaaaaaaa a              9351


<210>  542
<211>  3506
<212>  DNA
<213>  homo sapiens

<400>  542
tttcaaacag cggaacaaac tgaaagctcc ggtgccagac cccacccccg gccccggccc       60

gggaccccct cccctcccgg gatcccccgg ggttcccacc ccgcccgcac cgccggggac      120

ccggccggtc cggcgcgagc ccccgtccgg ggccctggct cggcccccag gttggaggag      180

cccggagccc gccttcggag ctacggccta acggcggcgg cgactgcagt ctggagggtc      240

cacacttgtg attctcaatg gagagtgaaa acgcagattc ataatgaaaa ctagcccccg      300

tcggccactg attctcaaaa gacggaggct gccccttcct gttcaaaatg ccccaagtga      360

aacatcagag gaggaaccta agagatcccc tgcccaacag gagtctaatc aagcagaggc      420

ctccaaggaa gtggcagagt ccaactcttg caagtttcca gctgggatca agattattaa      480

ccaccccacc atgcccaaca cgcaagtagt ggccatcccc aacaatgcta atattcacag      540

catcatcaca gcactgactg ccaagggaaa agagagtggc agtagtgggc ccaacaaatt      600

catcctcatc agctgtgggg gagccccaac tcagcctcca ggactccggc ctcaaaccca      660

aaccagctat gatgccaaaa ggacagaagt gaccctggag accttgggac caaaacctgc      720

agctagggat gtgaatcttc ctagaccacc tggagccctt tgcgagcaga aacgggagac      780

ctgtgcagat ggtgaggcag caggctgcac tatcaacaat agcctatcca acatccagtg      840

gcttcgaaag atgagttctg atggactggg ctcccgcagc atcaagcaag agatggagga      900

aaaggagaat tgtcacctgg agcagcgaca ggttaaggtt gaggagcctt cgagaccatc      960

agcgtcctgg cagaactctg tgtctgagcg gccaccctac tcttacatgg ccatgataca     1020

attcgccatc aacagcactg agaggaagcg catgactttg aaagacatct atacgtggat     1080

tgaggaccac tttccctact ttaagcacat tgccaagcca ggctggaaga actccatccg     1140

ccacaacctt tccctgcacg acatgtttgt ccgggagacg tctgccaatg gcaaggtctc     1200

cttctggacc attcacccca gtgccaaccg ctacttgaca ttggaccagg tgtttaagca     1260

gcagaaacga ccgaatccag agctccgccg gaacatgacc atcaaaaccg aactccccct     1320

gggcgcacgg cggaagatga agccactgct accacgggtc agctcatacc tggtacctat     1380

ccagttcccg gtgaaccagt cactggtgtt gcagccctcg gtgaaggtgc cattgcccct     1440

ggcggcttcc ctcatgagct cagagcttgc ccgccatagc aagcgagtcc gcattgcccc     1500

caaggtgctg ctagctgagg aggggatagc tcctctttct tctgcaggac cagggaaaga     1560

ggagaaactc ctgtttggag aagggttttc tcctttgctt ccagttcaga ctatcaagga     1620

ggaagaaatc cagcctgggg aggaaatgcc acacttagcg agacccatca aagtggagag     1680

ccctcccttg gaagagtggc cctccccggc cccatctttc aaagaggaat catctcactc     1740

ctgggaggat tcgtcccaat ctcccacccc aagacccaag aagtcctaca gtgggcttag     1800

gtccccaacc cggtgtgtct cggaaatgct tgtgattcaa cacagggaga ggagggagag     1860

gagccggtct cggaggaaac agcatctact gcctccctgt gtggatgagc cggagctgct     1920

cttctcagag gggcccagta cttcccgctg ggccgcagag ctcccgttcc cagcagactc     1980

ctctgaccct gcctcccagc tcagctactc ccaggaagtg ggaggacctt ttaagacacc     2040

cattaaggaa acgctgccca tctcctccac cccgagcaaa tctgtcctcc ccagaacccc     2100

tgaatcctgg aggctcacgc ccccagccaa agtaggggga ctggatttca gcccagtaca     2160

aacctcccag ggtgcctctg accccttgcc tgaccccctg gggctgatgg atctcagcac     2220

cactcccttg caaagtgctc ccccccttga atcaccgcaa aggctcctca gttcagaacc     2280

cttagacctc atctccgtcc cctttggcaa ctcttctccc tcagatatag acgtccccaa     2340

gccaggctcc ccggagccac aggtttctgg ccttgcagcc aatcgttctc tgacagaagg     2400

cctggtcctg gacacaatga atgacagcct cagcaagatc ctgctggaca tcagctttcc     2460

tggcctggac gaggacccac tgggccctga caacatcaac tggtcccagt ttattcctga     2520

gctacagtag agccctgccc ttgcccctgt gctcaagctg tccaccatcc cgggcactcc     2580

aaggctcagt gcaccccaag cctctgagtg aggacagcag gcagggactg ttctgctcct     2640

catagctccc tgctgcctga ttatgcaaaa gtagcagtca caccctagcc actgctggga     2700

ccttgtgttc cccaagagta tctgattcct ctgctgtccc tgccaggagc tgaagggtgg     2760

gaacaacaaa ggcaatggtg aaaagagatt aggaaccccc cagcctgttt ccattctctg     2820

cccagcagtc tcttaccttc cctgatcttt gcagggtggt ccgtgtaaat agtataaatt     2880

ctccaaatta tcctctaatt ataaatgtaa gcttatttcc ttagatcatt atccagagac     2940

tgccagaagg tgggtaggat gacctggggt ttcaattgac ttctgttcct tgcttttagt     3000

tttgatagaa gggaagacct gcagtgcacg gtttcttcca ggctgaggta cctggatctt     3060

gggttcttca ctgcagggac ccagacaagt ggatctgctt gccagagtcc tttttgcccc     3120

tccctgccac ctccccgtgt ttccaagtca gctttcctgc aagaagaaat cctggttaaa     3180

aaagtctttt gtattgggtc aggagttgaa tttggggtgg gaggatggat gcaactgaag     3240

cagagtgtgg gtgcccagat gtgcgctatt agatgtttct ctgataatgt ccccaatcat     3300

accagggaga ctggcattga cgagaactca ggtggaggct tgagaaggcc gaaagggccc     3360

ctgacctgcc tggcttcctt agcttgcccc tcagctttgc aaagagccac cctaggcccc     3420

agctgaccgc atgggtgtga gccagcttga gaacactaac tactcaataa aagcgaaggt     3480

ggacatgaaa aaaaaaaaaa aaaaaa                                          3506


<210>  543
<211>  3665
<212>  DNA
<213>  homo sapiens

<400>  543
tttcaaacag cggaacaaac tgaaagctcc ggtgccagac cccacccccg gccccggccc       60

gggaccccct cccctcccgg gatcccccgg ggttcccacc ccgcccgcac cgccggggac      120

ccggccggtc cggcgcgagc ccccgtccgg ggccctggct cggcccccag gttggaggag      180

cccggagccc gccttcggag ctacggccta acggcggcgg cgactgcagt ctggagggtc      240

cacacttgtg attctcaatg gagagtgaaa acgcagattc ataatgaaaa ctagcccccg      300

tcggccactg attctcaaaa gacggaggct gccccttcct gttcaaaatg ccccaagtga      360

aacatcagag gaggaaccta agagatcccc tgcccaacag gagtctaatc aagcagaggc      420

ctccaaggaa gtggcagagt ccaactcttg caagtttcca gctgggatca agattattaa      480

ccaccccacc atgcccaaca cgcaagtagt ggccatcccc aacaatgcta atattcacag      540

catcatcaca gcactgactg ccaagggaaa agagagtggc agtagtgggc ccaacaaatt      600

catcctcatc agctgtgggg gagccccaac tcagcctcca ggactccggc ctcaaaccca      660

aaccagctat gatgccaaaa ggacagaagt gaccctggag accttgggac caaaacctgc      720

agctagggat gtgaatcttc ctagaccacc tggagccctt tgcgagcaga aacgggagac      780

ctgtgcagat ggtgaggcag caggctgcac tatcaacaat agcctatcca acatccagtg      840

gcttcgaaag atgagttctg atggactggg ctcccgcagc atcaagcaag agatggagga      900

aaaggagaat tgtcacctgg agcagcgaca ggttaaggtt gaggagcctt cgagaccatc      960

agcgtcctgg cagaactctg tgtctgagcg gccaccctac tcttacatgg ccatgataca     1020

attcgccatc aacagcactg agaggaagcg catgactttg aaagacatct atacgtggat     1080

tgaggaccac tttccctact ttaagcacat tgccaagcca ggctggaaga actccatccg     1140

ccacaacctt tccctgcacg acatgtttgt ccgggagacg tctgccaatg gcaaggtctc     1200

cttctggacc attcacccca gtgccaaccg ctacttgaca ttggaccagg tgtttaagcc     1260

actggaccca gggtctccac aattgcccga gcacttggaa tcacagcaga aacgaccgaa     1320

tccagagctc cgccggaaca tgaccatcaa aaccgaactc cccctgggcg cacggcggaa     1380

gatgaagcca ctgctaccac gggtcagctc atacctggta cctatccagt tcccggtgaa     1440

ccagtcactg gtgttgcagc cctcggtgaa ggtgccattg cccctggcgg cttccctcat     1500

gagctcagag cttgcccgcc atagcaagcg agtccgcatt gcccccaagg tttttgggga     1560

acaggtggtg tttggttaca tgagtaagtt ctttagtggc gatctgcgag attttggtac     1620

acccatcacc agcttgttta attttatctt tctttgttta tcagtgctgc tagctgagga     1680

ggggatagct cctctttctt ctgcaggacc agggaaagag gagaaactcc tgtttggaga     1740

agggttttct cctttgcttc cagttcagac tatcaaggag gaagaaatcc agcctgggga     1800

ggaaatgcca cacttagcga gacccatcaa agtggagagc cctcccttgg aagagtggcc     1860

ctccccggcc ccatctttca aagaggaatc atctcactcc tgggaggatt cgtcccaatc     1920

tcccacccca agacccaaga agtcctacag tgggcttagg tccccaaccc ggtgtgtctc     1980

ggaaatgctt gtgattcaac acagggagag gagggagagg agccggtctc ggaggaaaca     2040

gcatctactg cctccctgtg tggatgagcc ggagctgctc ttctcagagg ggcccagtac     2100

ttcccgctgg gccgcagagc tcccgttccc agcagactcc tctgaccctg cctcccagct     2160

cagctactcc caggaagtgg gaggaccttt taagacaccc attaaggaaa cgctgcccat     2220

ctcctccacc ccgagcaaat ctgtcctccc cagaacccct gaatcctgga ggctcacgcc     2280

cccagccaaa gtagggggac tggatttcag cccagtacaa acctcccagg gtgcctctga     2340

ccccttgcct gaccccctgg ggctgatgga tctcagcacc actcccttgc aaagtgctcc     2400

cccccttgaa tcaccgcaaa ggctcctcag ttcagaaccc ttagacctca tctccgtccc     2460

ctttggcaac tcttctccct cagatataga cgtccccaag ccaggctccc cggagccaca     2520

ggtttctggc cttgcagcca atcgttctct gacagaaggc ctggtcctgg acacaatgaa     2580

tgacagcctc agcaagatcc tgctggacat cagctttcct ggcctggacg aggacccact     2640

gggccctgac aacatcaact ggtcccagtt tattcctgag ctacagtaga gccctgccct     2700

tgcccctgtg ctcaagctgt ccaccatccc gggcactcca aggctcagtg caccccaagc     2760

ctctgagtga ggacagcagg cagggactgt tctgctcctc atagctccct gctgcctgat     2820

tatgcaaaag tagcagtcac accctagcca ctgctgggac cttgtgttcc ccaagagtat     2880

ctgattcctc tgctgtccct gccaggagct gaagggtggg aacaacaaag gcaatggtga     2940

aaagagatta ggaacccccc agcctgtttc cattctctgc ccagcagtct cttaccttcc     3000

ctgatctttg cagggtggtc cgtgtaaata gtataaattc tccaaattat cctctaatta     3060

taaatgtaag cttatttcct tagatcatta tccagagact gccagaaggt gggtaggatg     3120

acctggggtt tcaattgact tctgttcctt gcttttagtt ttgatagaag ggaagacctg     3180

cagtgcacgg tttcttccag gctgaggtac ctggatcttg ggttcttcac tgcagggacc     3240

cagacaagtg gatctgcttg ccagagtcct ttttgcccct ccctgccacc tccccgtgtt     3300

tccaagtcag ctttcctgca agaagaaatc ctggttaaaa aagtcttttg tattgggtca     3360

ggagttgaat ttggggtggg aggatggatg caactgaagc agagtgtggg tgcccagatg     3420

tgcgctatta gatgtttctc tgataatgtc cccaatcata ccagggagac tggcattgac     3480

gagaactcag gtggaggctt gagaaggccg aaagggcccc tgacctgcct ggcttcctta     3540

gcttgcccct cagctttgca aagagccacc ctaggcccca gctgaccgca tgggtgtgag     3600

ccagcttgag aacactaact actcaataaa agcgaaggtg gacatgaaaa aaaaaaaaaa     3660

aaaaa                                                                 3665


<210>  544
<211>  3551
<212>  DNA
<213>  homo sapiens

<400>  544
tttcaaacag cggaacaaac tgaaagctcc ggtgccagac cccacccccg gccccggccc       60

gggaccccct cccctcccgg gatcccccgg ggttcccacc ccgcccgcac cgccggggac      120

ccggccggtc cggcgcgagc ccccgtccgg ggccctggct cggcccccag gttggaggag      180

cccggagccc gccttcggag ctacggccta acggcggcgg cgactgcagt ctggagggtc      240

cacacttgtg attctcaatg gagagtgaaa acgcagattc ataatgaaaa ctagcccccg      300

tcggccactg attctcaaaa gacggaggct gccccttcct gttcaaaatg ccccaagtga      360

aacatcagag gaggaaccta agagatcccc tgcccaacag gagtctaatc aagcagaggc      420

ctccaaggaa gtggcagagt ccaactcttg caagtttcca gctgggatca agattattaa      480

ccaccccacc atgcccaaca cgcaagtagt ggccatcccc aacaatgcta atattcacag      540

catcatcaca gcactgactg ccaagggaaa agagagtggc agtagtgggc ccaacaaatt      600

catcctcatc agctgtgggg gagccccaac tcagcctcca ggactccggc ctcaaaccca      660

aaccagctat gatgccaaaa ggacagaagt gaccctggag accttgggac caaaacctgc      720

agctagggat gtgaatcttc ctagaccacc tggagccctt tgcgagcaga aacgggagac      780

ctgtgcagat ggtgaggcag caggctgcac tatcaacaat agcctatcca acatccagtg      840

gcttcgaaag atgagttctg atggactggg ctcccgcagc atcaagcaag agatggagga      900

aaaggagaat tgtcacctgg agcagcgaca ggttaaggtt gaggagcctt cgagaccatc      960

agcgtcctgg cagaactctg tgtctgagcg gccaccctac tcttacatgg ccatgataca     1020

attcgccatc aacagcactg agaggaagcg catgactttg aaagacatct atacgtggat     1080

tgaggaccac tttccctact ttaagcacat tgccaagcca ggctggaaga actccatccg     1140

ccacaacctt tccctgcacg acatgtttgt ccgggagacg tctgccaatg gcaaggtctc     1200

cttctggacc attcacccca gtgccaaccg ctacttgaca ttggaccagg tgtttaagcc     1260

actggaccca gggtctccac aattgcccga gcacttggaa tcacagcaga aacgaccgaa     1320

tccagagctc cgccggaaca tgaccatcaa aaccgaactc cccctgggcg cacggcggaa     1380

gatgaagcca ctgctaccac gggtcagctc atacctggta cctatccagt tcccggtgaa     1440

ccagtcactg gtgttgcagc cctcggtgaa ggtgccattg cccctggcgg cttccctcat     1500

gagctcagag cttgcccgcc atagcaagcg agtccgcatt gcccccaagg tgctgctagc     1560

tgaggagggg atagctcctc tttcttctgc aggaccaggg aaagaggaga aactcctgtt     1620

tggagaaggg ttttctcctt tgcttccagt tcagactatc aaggaggaag aaatccagcc     1680

tggggaggaa atgccacact tagcgagacc catcaaagtg gagagccctc ccttggaaga     1740

gtggccctcc ccggccccat ctttcaaaga ggaatcatct cactcctggg aggattcgtc     1800

ccaatctccc accccaagac ccaagaagtc ctacagtggg cttaggtccc caacccggtg     1860

tgtctcggaa atgcttgtga ttcaacacag ggagaggagg gagaggagcc ggtctcggag     1920

gaaacagcat ctactgcctc cctgtgtgga tgagccggag ctgctcttct cagaggggcc     1980

cagtacttcc cgctgggccg cagagctccc gttcccagca gactcctctg accctgcctc     2040

ccagctcagc tactcccagg aagtgggagg accttttaag acacccatta aggaaacgct     2100

gcccatctcc tccaccccga gcaaatctgt cctccccaga acccctgaat cctggaggct     2160

cacgccccca gccaaagtag ggggactgga tttcagccca gtacaaacct cccagggtgc     2220

ctctgacccc ttgcctgacc ccctggggct gatggatctc agcaccactc ccttgcaaag     2280

tgctcccccc cttgaatcac cgcaaaggct cctcagttca gaacccttag acctcatctc     2340

cgtccccttt ggcaactctt ctccctcaga tatagacgtc cccaagccag gctccccgga     2400

gccacaggtt tctggccttg cagccaatcg ttctctgaca gaaggcctgg tcctggacac     2460

aatgaatgac agcctcagca agatcctgct ggacatcagc tttcctggcc tggacgagga     2520

cccactgggc cctgacaaca tcaactggtc ccagtttatt cctgagctac agtagagccc     2580

tgcccttgcc cctgtgctca agctgtccac catcccgggc actccaaggc tcagtgcacc     2640

ccaagcctct gagtgaggac agcaggcagg gactgttctg ctcctcatag ctccctgctg     2700

cctgattatg caaaagtagc agtcacaccc tagccactgc tgggaccttg tgttccccaa     2760

gagtatctga ttcctctgct gtccctgcca ggagctgaag ggtgggaaca acaaaggcaa     2820

tggtgaaaag agattaggaa ccccccagcc tgtttccatt ctctgcccag cagtctctta     2880

ccttccctga tctttgcagg gtggtccgtg taaatagtat aaattctcca aattatcctc     2940

taattataaa tgtaagctta tttccttaga tcattatcca gagactgcca gaaggtgggt     3000

aggatgacct ggggtttcaa ttgacttctg ttccttgctt ttagttttga tagaagggaa     3060

gacctgcagt gcacggtttc ttccaggctg aggtacctgg atcttgggtt cttcactgca     3120

gggacccaga caagtggatc tgcttgccag agtccttttt gcccctccct gccacctccc     3180

cgtgtttcca agtcagcttt cctgcaagaa gaaatcctgg ttaaaaaagt cttttgtatt     3240

gggtcaggag ttgaatttgg ggtgggagga tggatgcaac tgaagcagag tgtgggtgcc     3300

cagatgtgcg ctattagatg tttctctgat aatgtcccca atcataccag ggagactggc     3360

attgacgaga actcaggtgg aggcttgaga aggccgaaag ggcccctgac ctgcctggct     3420

tccttagctt gcccctcagc tttgcaaaga gccaccctag gccccagctg accgcatggg     3480

tgtgagccag cttgagaaca ctaactactc aataaaagcg aaggtggaca tgaaaaaaaa     3540

aaaaaaaaaa a                                                          3551


<210>  545
<211>  3506
<212>  DNA
<213>  homo sapiens

<400>  545
tttcaaacag cggaacaaac tgaaagctcc ggtgccagac cccacccccg gccccggccc       60

gggaccccct cccctcccgg gatcccccgg ggttcccacc ccgcccgcac cgccggggac      120

ccggccggtc cggcgcgagc ccccgtccgg ggccctggct cggcccccag gttggaggag      180

cccggagccc gccttcggag ctacggccta acggcggcgg cgactgcagt ctggagggtc      240

cacacttgtg attctcaatg gagagtgaaa acgcagattc ataatgaaaa ctagcccccg      300

tcggccactg attctcaaaa gacggaggct gccccttcct gttcaaaatg ccccaagtga      360

aacatcagag gaggaaccta agagatcccc tgcccaacag gagtctaatc aagcagaggc      420

ctccaaggaa gtggcagagt ccaactcttg caagtttcca gctgggatca agattattaa      480

ccaccccacc atgcccaaca cgcaagtagt ggccatcccc aacaatgcta atattcacag      540

catcatcaca gcactgactg ccaagggaaa agagagtggc agtagtgggc ccaacaaatt      600

catcctcatc agctgtgggg gagccccaac tcagcctcca ggactccggc ctcaaaccca      660

aaccagctat gatgccaaaa ggacagaagt gaccctggag accttgggac caaaacctgc      720

agctagggat gtgaatcttc ctagaccacc tggagccctt tgcgagcaga aacgggagac      780

ctgtgcagat ggtgaggcag caggctgcac tatcaacaat agcctatcca acatccagtg      840

gcttcgaaag atgagttctg atggactggg ctcccgcagc atcaagcaag agatggagga      900

aaaggagaat tgtcacctgg agcagcgaca ggttaaggtt gaggagcctt cgagaccatc      960

agcgtcctgg cagaactctg tgtctgagcg gccaccctac tcttacatgg ccatgataca     1020

attcgccatc aacagcactg agaggaagcg catgactttg aaagacatct atacgtggat     1080

tgaggaccac tttccctact ttaagcacat tgccaagcca ggctggaaga actccatccg     1140

ccacaacctt tccctgcacg acatgtttgt ccgggagacg tctgccaatg gcaaggtctc     1200

cttctggacc attcacccca gtgccaaccg ctacttgaca ttggaccagg tgtttaagca     1260

gcagaaacga ccgaatccag agctccgccg gaacatgacc atcaaaaccg aactccccct     1320

gggcgcacgg cggaagatga agccactgct accacgggtc agctcatacc tggtacctat     1380

ccagttcccg gtgaaccagt cactggtgtt gcagccctcg gtgaaggtgc cattgcccct     1440

ggcggcttcc ctcatgagct cagagcttgc ccgccatagc aagcgagtcc gcattgcccc     1500

caaggtgctg ctagctgagg aggggatagc tcctctttct tctgcaggac cagggaaaga     1560

ggagaaactc ctgtttggag aagggttttc tcctttgctt ccagttcaga ctatcaagga     1620

ggaagaaatc cagcctgggg aggaaatgcc acacttagcg agacccatca aagtggagag     1680

ccctcccttg gaagagtggc cctccccggc cccatctttc aaagaggaat catctcactc     1740

ctgggaggat tcgtcccaat ctcccacccc aagacccaag aagtcctaca gtgggcttag     1800

gtccccaacc cggtgtgtct cggaaatgct tgtgattcaa cacagggaga ggagggagag     1860

gagccggtct cggaggaaac agcatctact gcctccctgt gtggatgagc cggagctgct     1920

cttctcagag gggcccagta cttcccgctg ggccgcagag ctcccgttcc cagcagactc     1980

ctctgaccct gcctcccagc tcagctactc ccaggaagtg ggaggacctt ttaagacacc     2040

cattaaggaa acgctgccca tctcctccac cccgagcaaa tctgtcctcc ccagaacccc     2100

tgaatcctgg aggctcacgc ccccagccaa agtaggggga ctggatttca gcccagtaca     2160

aacctcccag ggtgcctctg accccttgcc tgaccccctg gggctgatgg atctcagcac     2220

cactcccttg caaagtgctc ccccccttga atcaccgcaa aggctcctca gttcagaacc     2280

cttagacctc atctccgtcc cctttggcaa ctcttctccc tcagatatag acgtccccaa     2340

gccaggctcc ccggagccac aggtttctgg ccttgcagcc aatcgttctc tgacagaagg     2400

cctggtcctg gacacaatga atgacagcct cagcaagatc ctgctggaca tcagctttcc     2460

tggcctggac gaggacccac tgggccctga caacatcaac tggtcccagt ttattcctga     2520

gctacagtag agccctgccc ttgcccctgt gctcaagctg tccaccatcc cgggcactcc     2580

aaggctcagt gcaccccaag cctctgagtg aggacagcag gcagggactg ttctgctcct     2640

catagctccc tgctgcctga ttatgcaaaa gtagcagtca caccctagcc actgctggga     2700

ccttgtgttc cccaagagta tctgattcct ctgctgtccc tgccaggagc tgaagggtgg     2760

gaacaacaaa ggcaatggtg aaaagagatt aggaaccccc cagcctgttt ccattctctg     2820

cccagcagtc tcttaccttc cctgatcttt gcagggtggt ccgtgtaaat agtataaatt     2880

ctccaaatta tcctctaatt ataaatgtaa gcttatttcc ttagatcatt atccagagac     2940

tgccagaagg tgggtaggat gacctggggt ttcaattgac ttctgttcct tgcttttagt     3000

tttgatagaa gggaagacct gcagtgcacg gtttcttcca ggctgaggta cctggatctt     3060

gggttcttca ctgcagggac ccagacaagt ggatctgctt gccagagtcc tttttgcccc     3120

tccctgccac ctccccgtgt ttccaagtca gctttcctgc aagaagaaat cctggttaaa     3180

aaagtctttt gtattgggtc aggagttgaa tttggggtgg gaggatggat gcaactgaag     3240

cagagtgtgg gtgcccagat gtgcgctatt agatgtttct ctgataatgt ccccaatcat     3300

accagggaga ctggcattga cgagaactca ggtggaggct tgagaaggcc gaaagggccc     3360

ctgacctgcc tggcttcctt agcttgcccc tcagctttgc aaagagccac cctaggcccc     3420

agctgaccgc atgggtgtga gccagcttga gaacactaac tactcaataa aagcgaaggt     3480

ggacatgaaa aaaaaaaaaa aaaaaa                                          3506


<210>  546
<211>  3365
<212>  DNA
<213>  homo sapiens

<400>  546
aaaaggggga gggaactgcg gctaaggaga cgttcggtga tgggagcgca atatatgagg       60

ggatacagtg cctcaggttt aaaagagcag gaagctgagt gagaggttgc agaaaaagtg      120

tcttcgctcg gcagaggtta caggtggcat ctcagaaaga gctttgaggc tacaggctgt      180

agtcgggaag gggatcggag aactgtgtga agggacagct tagggactag cgtcctggga      240

ctagggggaa gttcgcgact ttctgaagac tggcaggaat gtgcctcctg gccctcgatg      300

cttcccccct gaggggaggc atcgtgaggg actgtggcag gcttcactga acgctgagcc      360

ggggaggtcc aactccacgt atggatccgg ggaatgagaa ttcagccaca gaggctgccg      420

cgatcataga cctagatccc gacttcgaac cccagagccg tccccgctcc tgcacctggc      480

cccttccccg accagagatc gctaaccagc cgtccgagcc gcccgaggtg gagccagatc      540

tgggggaaaa ggtacacacg gaggggcgct cagagccgat cctgttgccc tctcggctcc      600

cagagccggc cgggggcccc cagcccggaa tcctgggggc tgtaacaggt cctcggaagg      660

gaggctcccg ccggaatgcc tggggaaatc agtcatatgc agaactcatc agccaggcca      720

ttgaaagcgc cccggagaag cgactgacac ttgcccagat ctacgagtgg atggtccgta      780

ctgtacccta cttcaaggac aagggtgaca gcaacagctc agcaggatgg aagaactcga      840

tccgccacaa cctgtccctg cacagcaagt tcatcaaggt tcacaacgag gccaccggca      900

aaagctcttg gtggatgctg aaccctgagg gaggcaagag cggcaaagcc ccccgccgcc      960

gggccgcctc catggatagc agcagcaagc tgctccgggg ccgcagtaaa gcccccaaga     1020

agaaaccatc tgtgctgcca gctccacccg aaggtgccac tccaacgagc cctgtcggcc     1080

actttgccaa gtggtcaggc agcccttgct ctcgaaaccg tgaagaagcc gatatgtgga     1140

ccaccttccg tccacgaagc agttcaaatg ccagcagtgt cagcacccgg ctgtccccct     1200

tgaggccaga gtctgaggtg ctggcggagg aaataccagc ttcagtcagc agttatgcag     1260

ggggtgtccc tcccaccctc aatgaaggtc tagagctgtt agatgggctc aatctcacct     1320

cttcccattc cctgctatct cggagtggtc tctctggctt ctctttgcag catcctgggg     1380

ttaccggccc cttacacacc tacagcagct cccttttcag cccagcagag gggcccctgt     1440

cagcaggaga agggtgcttc tccagctccc aggctctgga ggccctgctc acctctgata     1500

cgccaccacc ccctgctgac gtcctcatga cccaggtaga tcccattctg tcccaggctc     1560

cgactcttct gttgctgggg gggcttcctt cctccagtaa gctggccacg ggcgtcggcc     1620

tgtgtcccaa gcccctagag gctccaggcc ccagcagtct ggttcccacc ctttctatga     1680

tagcaccacc tccagtcatg gcaagtgccc ccatccccaa ggctctgggg actcctgtgc     1740

tcacaccccc tactgaagct gcaagccaag acagaatgcc tcaggatcta gatcttgata     1800

tgtatatgga gaacctggag tgtgacatgg ataacatcat cagtgacctc atggatgagg     1860

gcgagggact ggacttcaac tttgagccag atccctgagt catgcctgga agctttgtcc     1920

cctgcttcag atgtggagcc aggcgtgttc atatctactc tttacccttg agccctcccc     1980

aggaatttgg gaccctgctt tagagctagg gtggggtctg gtcacacaca ggtgttgaag     2040

aaattataaa gataaagctg ccccatctgg ggacgatatg gggagggaga tgggagggga     2100

aaggggagag ggtttttctc actgtgccaa ttagggggta aggccccctc tcaggagcca     2160

tcatcggctt tccccattcc tacccactta ggctttgtag caagatgagc aatgctgttg     2220

gaaatgtgaa gtcaccagtg gccttacccc tgcctttggg agcaggattt ttttgtagag     2280

agtcttatct gagctgagcc aggctagctg gagcctggga tttctatgca gtggcccctt     2340

aggccagtga tgtgcggtgg gtgggctgtt taggggatct ggaagggcca aggtctgagc     2400

actggagtgg ctcgccaggc caaatcaccc ttagaaggct gcagataaca gaaaggcttt     2460

ttataaactt ttaaagaaat ataaacacaa atatagagat tttttaacca tggcagggtg     2520

ctagtggtgg gcagaatgct tttttttctt tctgaaggct ttgtgatagt gacatgatac     2580

aaacactaca gacaataaat attaggagac acagggaagt ggggagaggt ggggagtaat     2640

agtaaacaca gggaagagct cccctacgga ccaggtatag agaaaggtct atgcagaaat     2700

aggttagagt ttccctaaca aaaaagctaa cccaggtccc ctcattcctt caacttgtgc     2760

ctgggagtgt gtggtgttag ggtgcagcca cactcttcta tgacccagca tgggttagtg     2820

ctatggtggg agagtacatt gaaggcctgg aattagcttg gggccaggga agggactggg     2880

aggggagaga agagaaggag ggaaggattt aggatggtaa agttaggtac agagacctcc     2940

ctgttcaagg cccctgacag ctgtccctgc ccttcttccc cttccctgac tgcaggggtt     3000

atgtggaagt gtgtgtggca gcaggcagcg gggaggggag gaacagggaa gggggagctg     3060

gggagcttgg ctgagggtct gggaaatgag cagggatggg gggggatgtg gatcaggttt     3120

actagcacct gccagggagg ccatctgggg ctccttctcc accccagccc ccaaagcagc     3180

ccttccccca gtgccctttg catcgtcccc tcccccaccc ctgctgtggg ttcccatcat     3240

ttcctgtgtc agcgcctggc ctacccagat tgtatcatgt gctagattgg agtggggaag     3300

tgtgtcaaat caataaatga ataaattcaa taaatgccta taaccagcaa aaaaaaaaaa     3360

aaaaa                                                                 3365


<210>  547
<211>  3200
<212>  DNA
<213>  homo sapiens

<400>  547
aaaaggggga gggaactgcg gctaaggaga cgttcggtga tgggagcgca atatatgagg       60

ggatacagtg cctcaggttt aaaagagcag gaagctgagt gagaggttgc agaaaaagtg      120

tcttcgctcg gcagaggtta caggtggcat ctcagaaaga gctttgaggc tacaggctgt      180

agtcgggaag gggatcggag aactgtgtga agggacagct tagggactag cgtcctggga      240

ctagggggaa gttcgcgact ttctgaagac tggcaggaat gtgcctcctg gccctcgatg      300

cttcccccct gaggggaggc atcgtgaggg actgtggcag gcttcactga acgctgagcc      360

ggggaggtcc aactccacgt atggatccgg ggaatgagaa ttcagccaca gaggctgccg      420

cgatcataga cctagatccc gacttcgaac cccagagccg tccccgctcc tgcacctggc      480

cccttccccg accagagatc gctaaccagc cgtccgagcc gcccgaggtg gagccagatc      540

tgggggaaaa ggccattgaa agcgccccgg agaagcgact gacacttgcc cagatctacg      600

agtggatggt ccgtactgta ccctacttca aggacaaggg tgacagcaac agctcagcag      660

gatggaagaa ctcgatccgc cacaacctgt ccctgcacag caagttcatc aaggttcaca      720

acgaggccac cggcaaaagc tcttggtgga tgctgaaccc tgagggaggc aagagcggca      780

aagccccccg ccgccgggcc gcctccatgg atagcagcag caagctgctc cggggccgca      840

gtaaagcccc caagaagaaa ccatctgtgc tgccagctcc acccgaaggt gccactccaa      900

cgagccctgt cggccacttt gccaagtggt caggcagccc ttgctctcga aaccgtgaag      960

aagccgatat gtggaccacc ttccgtccac gaagcagttc aaatgccagc agtgtcagca     1020

cccggctgtc ccccttgagg ccagagtctg aggtgctggc ggaggaaata ccagcttcag     1080

tcagcagtta tgcagggggt gtccctccca ccctcaatga aggtctagag ctgttagatg     1140

ggctcaatct cacctcttcc cattccctgc tatctcggag tggtctctct ggcttctctt     1200

tgcagcatcc tggggttacc ggccccttac acacctacag cagctccctt ttcagcccag     1260

cagaggggcc cctgtcagca ggagaagggt gcttctccag ctcccaggct ctggaggccc     1320

tgctcacctc tgatacgcca ccaccccctg ctgacgtcct catgacccag gtagatccca     1380

ttctgtccca ggctccgact cttctgttgc tgggggggct tccttcctcc agtaagctgg     1440

ccacgggcgt cggcctgtgt cccaagcccc tagaggctcc aggccccagc agtctggttc     1500

ccaccctttc tatgatagca ccacctccag tcatggcaag tgcccccatc cccaaggctc     1560

tggggactcc tgtgctcaca ccccctactg aagctgcaag ccaagacaga atgcctcagg     1620

atctagatct tgatatgtat atggagaacc tggagtgtga catggataac atcatcagtg     1680

acctcatgga tgagggcgag ggactggact tcaactttga gccagatccc tgagtcatgc     1740

ctggaagctt tgtcccctgc ttcagatgtg gagccaggcg tgttcatatc tactctttac     1800

ccttgagccc tccccaggaa tttgggaccc tgctttagag ctagggtggg gtctggtcac     1860

acacaggtgt tgaagaaatt ataaagataa agctgcccca tctggggacg atatggggag     1920

ggagatggga ggggaaaggg gagagggttt ttctcactgt gccaattagg gggtaaggcc     1980

ccctctcagg agccatcatc ggctttcccc attcctaccc acttaggctt tgtagcaaga     2040

tgagcaatgc tgttggaaat gtgaagtcac cagtggcctt acccctgcct ttgggagcag     2100

gatttttttg tagagagtct tatctgagct gagccaggct agctggagcc tgggatttct     2160

atgcagtggc cccttaggcc agtgatgtgc ggtgggtggg ctgtttaggg gatctggaag     2220

ggccaaggtc tgagcactgg agtggctcgc caggccaaat cacccttaga aggctgcaga     2280

taacagaaag gctttttata aacttttaaa gaaatataaa cacaaatata gagatttttt     2340

aaccatggca gggtgctagt ggtgggcaga atgctttttt ttctttctga aggctttgtg     2400

atagtgacat gatacaaaca ctacagacaa taaatattag gagacacagg gaagtgggga     2460

gaggtgggga gtaatagtaa acacagggaa gagctcccct acggaccagg tatagagaaa     2520

ggtctatgca gaaataggtt agagtttccc taacaaaaaa gctaacccag gtcccctcat     2580

tccttcaact tgtgcctggg agtgtgtggt gttagggtgc agccacactc ttctatgacc     2640

cagcatgggt tagtgctatg gtgggagagt acattgaagg cctggaatta gcttggggcc     2700

agggaaggga ctgggagggg agagaagaga aggagggaag gatttaggat ggtaaagtta     2760

ggtacagaga cctccctgtt caaggcccct gacagctgtc cctgcccttc ttccccttcc     2820

ctgactgcag gggttatgtg gaagtgtgtg tggcagcagg cagcggggag gggaggaaca     2880

gggaaggggg agctggggag cttggctgag ggtctgggaa atgagcaggg atgggggggg     2940

atgtggatca ggtttactag cacctgccag ggaggccatc tggggctcct tctccacccc     3000

agcccccaaa gcagcccttc ccccagtgcc ctttgcatcg tcccctcccc cacccctgct     3060

gtgggttccc atcatttcct gtgtcagcgc ctggcctacc cagattgtat catgtgctag     3120

attggagtgg ggaagtgtgt caaatcaata aatgaataaa ttcaataaat gcctataacc     3180

agcaaaaaaa aaaaaaaaaa                                                 3200


<210>  548
<211>  5570
<212>  DNA
<213>  homo sapiens

<400>  548
agcagttcag agccccagtt gcagacgact tgtcctgcca ccaccatgag ttctgaatgt       60

gatggtggtt ccaaagctgt gatgaatggc ttggcacctg gcagcaatgg gcaagacaaa      120

gacatggatc ctacaaaaat ctgcactggg aagggagcgg tgactctccg ggcctcgtct      180

tcctacaggg aaaccccaag cagtagccct gcgagccctc aggaaacccg gcaacacgaa      240

agcaaaccag atgagtggag gctttcttcc agtgctgatg ccaatggaaa tgcccagccc      300

tcttcactcg ctgccaaggg ctacagaagt gtgcatccca accttccttc tgacaagtcc      360

caggattcca gtcctctact aaatgaagtt tcttcttccc ttattggaac tgattcccaa      420

gcctttccat cagttagcaa gccttcatcc gcctatccct ccacaacgat tgtcaatcct      480

actattgtgc tcttgcaaca caatcgagaa cagcaaaaac gactcagtag cctttcagat      540

cctgtctcag aaagaagagt gggagagcag gactcagcac caacccagga aaaacccacc      600

tcacctggca aggctattga aaaaagagca aaggatgaca gtaggcgggt ggtgaagagc      660

actcaggact taagcgatgt ttccatggat gaagtgggca tcccactccg gaacactgag      720

agatcaaaag actggtacaa gactatgttt aaacagatcc acaaactgaa cagagatgat      780

gattcagatc tgtactctcc cagatactca ttttctgaag acacaaaatc tcccctttct      840

gtgcctcgct caaaaagtga gatgagctac attgatggtg agaaggtagt caagaggtcg      900

gccacactac ccctcccagc ccgctcttcc tcactgaagt caagctcaga aagaaatgac      960

tgggaacccc cagataagaa agtagacaca agaaaatatc gtgcagagcc caagagcatt     1020

tacgaatatc agcctggcaa gtcttccgtt ctgaccaacg aaaagatgag ctcagccatc     1080

agccctactc cggaaatttc ttcagagact cctggatata tatattcttc caacttccat     1140

gcagtgaaga gggaatcaga cggggctcct ggggatctca ctagcttgga gaatgagaga     1200

caaatttata aaagtgtctt ggaaggtggt gacatccctc ttcagggcct gagtgggctc     1260

aagcgaccat ccagctctgc ttccactaaa gattcagaat cgccaagaca ttttatacca     1320

gctgattact tggaatccac ggaagaattt attcgaagac gtcatgatga taaagagaaa     1380

cttttagcgg accagagacg acttaaacgc gagcaagaag aggctgatat tgcagctcga     1440

cgccacacag gcgtcattcc gacgcaccat cagtttatca ctaatgagcg ctttggggac     1500

ctcctcaata tagacgatac tgcaaaaagg aaatctgggt cagagatgag acctgccaga     1560

gccaaatttg actttaaagc tcagacacta aaggagcttc ctctgcagaa gggagatatt     1620

gtttacattt ataagcaaat tgatcagaac tggtatgaag gagaacacca cggccgggtg     1680

ggaatcttcc cacgcaccta catcgagctt cttcctcctg ctgagaaggc acagcccaaa     1740

aagttgacac cagtgcaggt tttggaatat ggagaagcta ttgctaagtt taactttaat     1800

ggtgatacac aagtagaaat gtccttcaga aagggtgaga ggatcacact gctccggcag     1860

gtagatgaga actggtacga agggaggatc ccggggacat cccgacaagg catcttcccc     1920

atcacctacg tggatgtgat caagcgacca ctggtgaaaa accctgtgga ttacatggac     1980

ctgcctttct cctcctcccc aagtcgcagt gccactgcaa gcccacagca acctcaagcc     2040

cagcagcgaa gagtcacccc cgacaggagt caaacctcac aagatttatt tagctatcaa     2100

gcattatata gctatatacc acagaatgat gatgagttgg aactccgcga tggagatatc     2160

gttgatgtca tggaaaaatg tgacgatgga tggtttgttg gtacttcaag aaggacaaag     2220

cagtttggta cttttccagg caactatgta aaacctttgt atctataaga agactgaaaa     2280

ccatggagat tatttttatt ggaggaggaa gcatcattca tgaaccgatc tttttagttg     2340

agtcagtagg aaaattaata cagtggataa agtaagaagc aaaagacagg gacagagaag     2400

tgttgtgttt aaaacccaag cctgtctaag gttactgtgt attagacagg gccgaactag     2460

tgtgctgagc aaaaagaatt gaagcaaatt gtatttactt agccgcttct gggagccact     2520

tcagcctttc ccctcccctc cacttcttgg gtaatctgac ctgaagcata gtccaggagc     2580

agagttagcc agaaatgcct cctgctgccc cagccttaga gagctcccat ctcaatcatt     2640

gagcctgaag gcttcaagcc caagaatgca acaagacccc cagcctacat ttctcagctc     2700

ccctggagcc agctgatcct gtaacgctgc tggaggtcag tctgagctac caagactgtc     2760

cctagacaaa ggtggagtcc cccacactgc ccaagaccaa atccctcact caacctgctg     2820

aggtgtggat ggggaaacag aggcaaaact gaggcacctg atgcattcag cctgctgtgc     2880

agcagtgcca ttgactgccc tgatgttcag agagaaacgc acacaaggtt tgcccatgag     2940

aattggggag cagatggcca agcagatagg ttatgtctgt tttctgagtg atgaagtcag     3000

gaagccctgt ggctctggag gccacttgtg gttcattctt ttcccatatc cttggctttt     3060

agaaatggtt accttcagga cagtgcagct gcatttatca gagcactatt gctaagtttt     3120

cttttctggc ttgtgttttt ctgggacagt ttagaattgg gaggcctatt ctcatagaac     3180

accaaaaatg atgttcagtg attcatttaa catacaccaa tgtactctgg ctgctggggg     3240

gacaaccata agcaagacat gcccagggtt tgccgtggct ccagatctac tccctgtagg     3300

agttcaagga tcacacaaac ggtagtaacc agggttgtga atctgagtac accctggcaa     3360

ggcttctctt cagactgaag cagcaattct gccactacca gcagcaacca ggacgtctgt     3420

tctttgtggg ggccagatca gaagagagag gcccctgtga cgcccgggct gcttggtcac     3480

aactctgtcc aattcaagga tgtttatcgg cctctcttag atcctgagtg agacaaatac     3540

agaaatgacc cattccctgc ccaccagaaa ctcagaggtg attggggaga ctgacacagg     3600

aaaatgaact taatcaagag agactgtgat atgtgctaag aagggtgtga gggagggaga     3660

gatgaatttt ccctggaggg atcctagaaa gcattgtcat attgccatct ccattagctc     3720

acttttaaac aactagggtg ctggaagaac ctttgtctga gggtagttca tagctggaaa     3780

tacttggaat attttccaga gtctctaaac tctcatcttc ccccacagat acacatccaa     3840

gctcacaaat aggagtagca attctaggtg gtagggttgt gtacggaacc cctggctgtc     3900

tgcatatatc tcagaattac cccaggacca ttgtcccaaa gtctagagtc tttacaggta     3960

ggcaaaattt gttttcaatg cctgtgcctc agctgctgtc acaaataccc atcttaggat     4020

cccatcagct tcccatcccc caccagacag ccacagtacc ctcactttct ccctattgtt     4080

ctttcaaatc ctgttctcag gaaagaaact gccactaatt cattcacact aaggtgtaaa     4140

tgattgataa taggaatgag ttacctcttc ccacagacat ttgtttttaa gtatgacaga     4200

gcagggcctt aatcccaagg gaaaaggtta tggaactgga gggggtgagc tttctgggta     4260

gaaggagact tcctgaattt ccttaaaacc cagtaagagt aagacctgtt gttttggaag     4320

gtctgctcca ccatctaaga gcactgtttt tttttttttg ttgttgttgt tgttttacgg     4380

tctctgaggg aatatagtaa aaatgcatat gcacgtgcaa tttgcacggc agcatttcac     4440

cgattgtgga ctgtattggc taatgtgttt cctggtcttt agatgcaaac cattaataac     4500

actatcttat ctcatagttt tttcaggggt gcttcttgat tagtagggaa ttttgaacac     4560

ctctttaaat acagctagaa aataaaacca atttgtaaag ccacatttgc atatgatgcc     4620

agcctcacgc atttgtatat ctccagaaat tcaggtatgc ctcaccaatt tgcccgtctt     4680

taataaaatc ttgtgttaaa atttgcatca cgtcgccttc ctatgtatga cgaaacaaga     4740

aacagagatt tccaattgct cttttgtctt cagacattta gtaatataaa gtacctattt     4800

ttatgctgaa atgtttatac aggtttatta atagcaagtg caactaactg gcggcatgcc     4860

ttgcaacaca ttttgatata ttagccatgc ttccgggtaa aggcaagccc caaactcctt     4920

atcttttgca gtctctctgg gatcagtaaa agaaaaaaaa aataatgtgc ttaagaagtg     4980

ggactgtaaa tatgtatatt taactttgta tagcccatgt acctaccttg tatagaaaaa     5040

taattttaaa aatttgaatg gaagggggta aaggaagtca tgaagttttt ttgcattttt     5100

atttaaatga aggaattcca aataactcac ctacagattt ttagcacaaa aatagccatt     5160

gtaaagtgtt aaaatttacg ataagtattc tattggggag gaaaggtaac tctgatctca     5220

gttacagttt ttttttcctt tttaatttca ttattttggg tttttggttt ttgcagtcct     5280

atttatctgc agtcgtatta agtcctattg ctagaatagg ttactacaaa aaaggttata     5340

ttctgaaaga aaaataactg acattatata taaccaatta atttaaagta ttgccattta     5400

aattacacac tgagagcatg tcctatgcag acatagattt ttctgttcat ttatttttct     5460

tcattgcagt ggattgattt gataaataga tgtgttgaat tactacattt gctgtacata     5520

ttatttaata aactttattc agaattgcgt ggcaaaaaaa aaaaaaaaaa                5570


<210>  549
<211>  2931
<212>  DNA
<213>  homo sapiens

<400>  549
aagtaattgt ccgtgtcagg aaggtaggcg tgccaagccg cggctctgcg gagaaaccac       60

gaccaccgcg gccgccggaa acccaaagcg ctccagagcg tccccgggtg gccgggcagc      120

accagggaca gcgcccggga ctccactggg gaccggctcc tgggcttccc agcgtcgcgg      180

gtagaggtac agctgctccg tgtgccgcag gctccagatt ctcgccaccc cacccctccc      240

tcagaaactc ggactgctct cgtctgccgt gtggttctct tttcttccga aaggccagtg      300

tcttatctct ccacttcaag tccagaggac ttgctcagtc tcctcccctt aagtcatttc      360

caccatcctc aggcagctgt gggaagccga gagtcctgga ctgttcgtcc gggtgccagc      420

gctggcagtc ccagtccgtc cggtgcagca gcccggcgca ttcccctctc tccctccctc      480

ttgctctccc tccctttctg tcttcctctc tttcctcctc tactgctccc tccctctctt      540

gcctcttaag tttcctgcac cgtgaatcca actgtgccaa gccttggctc ccgcgaacca      600

atcctgagcg cgacccgggc actgggacgg cgactccgcc aaagctggac gaggcagccg      660

gacccgtctg cgctcgagca tggagacgga gcgcctggga gggcacgtcc ggggcgctgg      720

agacgccagg cccgagtagc ttctccatgg agcctgccca gagcggtccc ttctcgcagg      780

attcgcccca agtcctgtgc ggctgctgag agcgctcctt gctctgtaaa gtggatgtca      840

ggtggatcta tgtttctgaa ggaacaaaga ctcaaagaag gcaccgccaa ggaagtttga      900

gacgcgggag aatgcaggct gcgtgctggt acgtgctttt cctcctgcag cccaccgtct      960

acttggtcac atgtgccaat ttaacgaacg gtggaaagtc agaacttctg aaatcaggaa     1020

gcagcaaatc cacactaaag cacatatgga cagaaagcag caaagacttg tctatcagcc     1080

gactcctgtc acagactttt cgtggcaaag agaatgatac agatttggac ctgagatatg     1140

acaccccaga accttattct gagcaagacc tctgggactg gctgaggaac tccacagacc     1200

ttcaagagcc tcggcccagg gccaagagaa ggcccattgt taaaacgggc aagtttaaga     1260

aaatgtttgg atggggcgat tttcattcca acatcaaaac agtgaagctg aacctgttga     1320

taactgggaa aattgtagat catggcaatg ggacatttag tgtttatttc aggcataatt     1380

caactggtca agggaatgta tctgtcagct tggtaccccc tacaaaaatc gtggaatttg     1440

acttggcaca acaaaccgtg attgatgcca aagattccaa gtcttttaat tgtcgcattg     1500

aatatgaaaa ggttgacaag gctaccaaga acacactctg caactatgac ccttcaaaaa     1560

cctgttacca ggagcaaacc caaagtcatg tatcctggct ctgctccaag ccctttaagg     1620

tgatctgtat ttacatttcc ttttatagta cagattataa actggtacag aaagtgtgcc     1680

ctgactacaa ctaccacagt gacacacctt actttccctc gggatgaagg tgaacatggg     1740

ggtgagactg aagcctgagg aattaaaggt catatgacag ggctgttacc tcaaagaaga     1800

aggtcacatc tgttgcctgg aatgtgtcta cactgctgct cttgtcaact ggctgcaaaa     1860

tacactagtg gaaaacactc tgatgtaatt tctgcccagt cagcttcatc cctcagtata     1920

attgtaaatc atcacagatt ttgaattcac acctgaagac atgctctcac atatagaggt     1980

acacaaacac accgtcatgc acatttcagc ttgcgtctat catgattcct gttgagaggg     2040

ctttcattgt ctgactcata atggttcagg atcaactatc atcaaacgga aggattaact     2100

agacagagaa tgtttctaac agttgctgtt atggaaatct cttttaaagt cttgagtaca     2160

tgctaatcaa taatctccac tcatgcattc ctactgcttg gagtagctgt actggtaaat     2220

actactgtag gagtatctgc ttgttaaaat ggaaaaatgt gtctttagag ctcagtattc     2280

tttattttac aaacacaaca aaatgtagta acttttttcc agcatacagt aggcacattc     2340

aaagtggtcc aagatggctc ttttttcttt gaaaggggcc tgttctcagt aaagatgagc     2400

aaacatttgg aatttacatg tgggcagaca ttgggataac aactttcatc accaatcatt     2460

ggacttttgt gaagttgaca ccagctaagg ctgcttaaaa taagttctga tcattatata     2520

agaagggaaa tgcctggcag acaccatgta agttataagt gtctgtctta tctttactac     2580

acatattgta acaaattcaa tatcctagtc ttcatttgta tgaatggttt gtattgtaca     2640

tagtttaacc aagtgttatt tgagctgctt attaatatta acttgtactt gtctctctgc     2700

ttgttattgg ttaagaaaaa aggatatgag gaattcattt tatcaatgta gctgtgaagg     2760

ccattaaaaa gacaaactta atgtacagag catttattca gatcaagtat tgttgaaagc     2820

tatacatata caacattaca gtctgtctgt atttagatat tttatttctg gaaaaaatga     2880

aatgtacata aaaataaaac acttaaagtt gagtttcaat aaaaaaaaaa a              2931


<210>  550
<211>  2384
<212>  DNA
<213>  homo sapiens

<400>  550
attcctcgtt agggcaggcg cggccccttc ggctccgagc tgaccctgat cagggccgag       60

ttgtctcggc ggcgctgccg aggcctccac ccggggaggg tggttaccgc tgaggagctg      120

cagtctctgt caagatgata gaggtactga caacaactga ctctcagaaa ctgctacacc      180

agctgaatgc cctgttggaa caggagtcta gatgtcagcc aaaggtctgt ggtttgagac      240

taattgagtc tgcacacgat aatggcctca gaatgactgc aagactaagg gactttgaag      300

taaaagatct tcttagtcta actcagttct ttggctttga cacagagaca ttttctctag      360

ctgtgaattt actggacaga ttcctgtcta aaatgaaggt acagcccaag caccttgggt      420

gtgttggact gagctgcttt tatttggctg taaaatcaat agaagaggaa aggaatgtcc      480

cattggcaac tgacttgatc cgaataagtc aatataggtt tacggtttca gacttgatga      540

gaatggaaaa gattgtattg gagaaggtgt gttggaaagt caaagctact actgcctttc      600

aatttctgca actgtattat tcactccttc aagagaactt gccacttgaa aggagaaata      660

gcattaattt tgaaagacta gaagctcaac tgaaggcatg tcattgcagg atcatatttt      720

ctaaagcaaa gccttctgtg ttggcattgt ctatcattgc attagagatc caagcacaga      780

agtgtgtaga gttaacagaa ggaatagaat gtcttcagaa acattccaag ataaatggca      840

gagatctgac cttctggcaa gagcttgtat ccaaatgttt aactgaatat tcatcaaata      900

agtgttccaa accaaatgtt cagaagttga aatggattgt ttctgggcgt actgcacggc      960

aattgaagca tagctactac agaataactc accttccaac aattcctgaa atggtccctt     1020

aactggatta ttacagcacc aaaaaacttc tctgaagcct ttctccacaa ccttgttcta     1080

tggattccat aatgttacaa tggatttaag ctatgaagcc tcaaaacatc acgagataag     1140

catgatggtc tcagacttgg gaaaactgcc taatattatg ctgtagtgga attatgttta     1200

gatttgaatt catctgtgaa gcattcaaat caaagctaaa agcctaaatg tgaaatgcta     1260

atgacaagcc tgagaaggta aactgtgaat cttcatttct atcattgatc taactttaga     1320

tattggatca atatatttag gtggtattga aaatgctatt ggaggagtca cactaatact     1380

atcaactatc agtcttccca cagcttcaat cactgtcatt attctaatcc tactcctact     1440

taaattttaa gttatgaggt ttatgtcaaa agcaacattt cacaaatgta cttttaaggc     1500

ataataaggg ttaacattct aggcagtata aacacacccc ataatgcaag taataggtaa     1560

tctagagatg tggactttat tgctatatgg gaattacatt taaatttgag ggcattttat     1620

ataaagaaaa atacagacct ataaagtttg gcatattcat taagttatct tttaatattt     1680

ttttctagaa aacaggtgac atttgtatct acgataaaaa tttttataca gaacctactg     1740

cctcaaactg aatcccatca agaaaactag tttctattgt attagtaact caaaataaat     1800

tatcacttcg aaaacttgct ttcccacact aaggtaagtt cagactagat tgaacactcc     1860

agaatttttt actacagact gtttttaagt tagaagtgat ggcaatttta taaatagaga     1920

atatacttcc actgatgccc ttactgtgcc aaaacaaaaa tcttaagaaa agcaagtaga     1980

caccttcata actatgaatg aagctgctga agtagtgttt aggatcctcc atggcagtta     2040

gtgaatgtaa gaagtacagt gttaaagtgt tgtaaacagt tactcagtgc aatgtatagc     2100

ctgagtctat ccatgatggc tatatccaat ttgacatcac gttatggatc agtacacaat     2160

gaaaaaccaa agaaccacag tatatcttat tcttaacttt tgtaaaccat gttttatggg     2220

taacttttta gttttcccaa aaggctgata aatttcaata ttttgaatac atcattgtta     2280

attttgagtt ggcagaggta aactaaccaa ctaccattat gttttagtac taagggatat     2340

acctttcaat aaagttaatg aaattcaaaa aaaaaaaaaa aaaa                      2384


<210>  551
<211>  2253
<212>  DNA
<213>  homo sapiens

<400>  551
atctaatgag gagcgaggtg cggtgccccg aagcgctcgc ttcccgcggt gcgatctagt       60

cctgcagtag gcggcccggg gccacaccgc ggccgcccaa gccagtgcaa ggcccagggg      120

cctgacatcg ctcccagcgc tcgaggaccg aggcctgctg tggaggacac cgtgctccct      180

cgggacctgc tctggattcc ggcccggacg tccccttgga gctctgcatc tccaacctgg      240

aacccaaccc agaagtctca agtttgacgc atcacgtggc gtgcggatcc actgagggtc      300

cacagagagg ggcgcccatc tcctgcgtct cagttatcct ggtgttggga attctgtgcc      360

ctaaagaatt ccgactcaga tccgaacggg gatctggtgg aatcgagggt gaaagaccag      420

agggacaatg ttctactatc ccaacgtgct tcagcgccac accggctgct ttgccaccat      480

ctggctggcg gcgactcgcg gcagccggtt ggtgaagcgc gaatacctga gggtgaatgt      540

ggtgaaaacc tgcgaggaaa tcctcaatta cgtgctggta cgagtgcaac ccccgcagcc      600

cggcctgccg cggccccgct tctccctcta tctctcagcc caacttcaga tcggtgtgat      660

ccgcgtctat tctcaacaat gccagtacct cgtggaggac atccagcaca tcttggagcg      720

cctccaccgt gcccagctgc agatccgaat agatatggag actgagctac ccagcctgct      780

gcttcctaac cacctggcca tgatggagac cctagaagat gctccagatc ccttttttgg      840

gatgatgtct gtggatccca gacttcctag tcctttcgat atccctcaga ttcgacacct      900

cttagaggct gcaatcccag agagagttga agagatccct cctgaagttc ctacagagcc      960

cagggagcca gagaggattc cggtcactgt gctgccacct gaggccatca cgatcctgga     1020

ggcagagccc atacggatgc tggagattga gggtgaacgg gagctcccag aggtcagccg     1080

ccgagaactg gacctgctga tcgcagagga agaagaagct atcttgttag aaatcccgcg     1140

gctcccacct ccagctcctg cagaggtgga aggaatagga gaggcactgg gtcctgagga     1200

gctgaggctg acaggctggg aacctggggc cctactcatg gaggtgaccc ccccggagga     1260

gctgcgtctg ccagccccac ccagcccaga gaggaggccc ccagtccccc cacctcctcg     1320

ccgccgccgt cgtcgccggt tactgttctg ggacaaggag actcagatct ccccggagaa     1380

attccaggaa caactgcaaa ccagagccca ctgctgggaa tgtcctatgg tgcagccgcc     1440

cgagaggacc atcagaggcc ctgcggagtt gttcagaacc ccaactctct ctggctggct     1500

accccctgaa ctactgggtc tctggaccca ttgtgcccag ccacccccaa aagccctcag     1560

gcgagagctg cctgaggagg cagccgctga ggaggaaagg agaaagattg aagttccaag     1620

tgagattgag gtcccgaggg aggccctgga gcccagtgtt ccccttatgg tgtctttaga     1680

gatctcccta gaggcagctg aagaggagaa gtcccgcatc agcctcatcc caccagaaga     1740

acggtgggcc tggcctgagg tggaggcgcc agaagctcct gcattgcccg tggtgcctga     1800

actccctgag gtgcccatgg agatgccttt ggtgctgccc ccagagctcg agctgctctc     1860

actggaagca gtgcacaggg cagtggcact ggagctgcag gctaacaggg agcccgactt     1920

cagcagcctg gtgtcacctc tcagcccccg caggatggct gcccgggtct tctacctgct     1980

cctggtgctc tcagcgcaac agattcttca cgtgaaacaa gaaaagccat atggtcgcct     2040

cctgatccag ccggggccca gattccactg aggttagagt ccatttacaa agctgccagg     2100

aaaccggcca cttctagtaa accacgtcgt gcctcactgg gtcctgctta cctcatttct     2160

gaatgtgcat ttccagcctt cttgctctca gagctattgt tcaagcagaa aacaagctgc     2220

ttttattaca gtaaaaaaaa aaaaaaaaaa aaa                                  2253


<210>  552
<211>  2180
<212>  DNA
<213>  homo sapiens

<400>  552
aggaggcggt gcgtgcctcg cctgccaaag ggagatccgc tcctctgcgt gcgatccccg       60

gcgcccgcgc gcgcccacag cgctccgcca gagctgccgc cgcggactcg ccgggagtgg      120

gggtctccgc tggtgccagc ccgcttctgg agaccctccg cctcctgcca acccctgctc      180

ttccaggtcg ggccccgggg ttctgcggct gttagggaca gaggcaaaga agggcaggac      240

ggtccggttt cccgtggatg ttcccgcccg agaaagacag caagttgtgt gtgcgcccgg      300

gacgcgggag ggaaggtagc cgccgcccgc cagccatgga ccatcatctt tagtgcagag      360

gatggaaagt tgatgcccag taagactgaa gatccattct gcattacgga actgtggatt      420

atctgtgggt ccctggtgat ttcacacctt cattcactcc tgcagtccct gaacacttac      480

ttggggtcct cattgcccta tctggtgaaa gatggcatcc agcctgactt gtactggagt      540

aatctgggct ttgctgtctt ttctttgtgc tgccacctcc tgcgtggggt tctttatgcc      600

ttactggctc tggggatcac agctgggcaa gcctgtgtcc ttcggtacct tccggaggtg      660

ctcatatcct gtgcatgatg agagtcggca gatgatggtg atggtggagg aatgtgggcg      720

ctatgcctcc ttccagggca tccccagcgc agaatggagg atctgcacca tagtgaccgg      780

cctgggttgt ggcctcctcc tcctggtggc gctcactgcc ctcatgggtt gctgtgtttc      840

cgacctcatc tccaggacag tgggaagagt ggctggagga attcagtttc ttgggggctt      900

gttgattggt gctggctgtg ccctctaccc cttgggctgg gacagtgagg aagtccggca      960

gacttgtggc tacacttctg gccagtttga cctggggaag tgtgaaatcg gctgggccta     1020

ctactgcacg ggagcaggtg ccactgccgc catgctgctg tgcacgtggc tggcttgctt     1080

ttcgggcaag aaacagaagc actacccata ctgagatgga gctaccaaga gcagacagag     1140

gagaagatgg gccaaagggg cttggagagg tcaaaacatc cacctacctt caaaaggtgg     1200

gatagtagtt ctaatccaat acaatgctaa taaaatgaaa cccgataaaa tcaggaacat     1260

gatataggaa ggaaggattg taggagattt gtgggggaaa aaaaaggaga gtatagaatg     1320

atggagaaaa atggaccaaa ggctaaaaat attgcagggc atcgggtgtt tctattccac     1380

agagtattgt taatgtacaa cacacacaca cacacacaca cacacacaca cacacacaca     1440

cacacaacaa atctacatat acaaacaagg gtttgggttt tagttttttt tttttaaggt     1500

gaggactcag aaaatcaaag ggctagtaga aacagtgtta tgttgggaag cagggtaccc     1560

ccaaagatgt tccctgtagg tcacggcact cccaaaagca cacaagcaca tacagacata     1620

tgcatcccca cacacgccta tgcacaaacg tggattatcg cacagactgg gaggtttagt     1680

ggtgcatttc tcctctgttt tctttttaat atacatttaa aatacagtat tatcacttta     1740

taaaacatac attaagccta ataaatggac caataagcca aactatcagt attttgtata     1800

tcctgcataa actctaattt agttcctcaa catattttca gtgtttatgc agacctttag     1860

agttaagcct ttgtatttcc atgttattcc acaatatgca atatttctct gagtagcttc     1920

tgctatgata ttcttatgaa gaaaaggggc aactttctgt ccactatagg agagaattca     1980

gccgaagata tgagagtaat gagagacatt ttccagtcat tggatcgtgt tttcttttgt     2040

ccattattgt actgtgctgt accacattta tttctatatt cattttgtaa aaaatttaaa     2100

agtgctattt tgtttgtatt tgaaaatctc tgtgaataaa ttctctcttt gatcaataaa     2160

aaaaaaaaaa aaaaaaaaaa                                                 2180


<210>  553
<211>  6383
<212>  DNA
<213>  homo sapiens

<400>  553
cccgcaccca cctcccggcc ccaggcacac tgcatcggcg cggacgctcc ggccccggcg       60

aggtggctgc aaactcgcgg gcacgcacgg cgcccgggga gccgagggac tcgggggagg      120

ggacgcgcgc ggaaggcgcc agcttcctcc cgcccgcccc tggcagccgc gagccgaggt      180

tggaggcgcc cggggcccca gccgggcaga gccgagcggc ggcggcggcg gcggcttccc      240

ttttctcccc gagccgagcc ccggagcggc gcggggaccg gccctaaaaa gagcaggaaa      300

tcttgtttac cgcccgcgga gagaagccga tcgagccttt gtctggaaag tcagcatctc      360

cggctccggc tgcaatgtgt tcctggtgac attagcatcg ggcagacccg ccggaggagg      420

ggggtcgcca ggttcccgtc tgctttcgga ggcggatcga gcgggtgact tttgtgcatt      480

cgttttaatt tttggaaatc tctctttttt cctccctcgc tcgctgccgg gcatgtcctg      540

atctggcggc cgctcctacc accctgggca gccgagcaga gtcgtcccca gcgggtctcc      600

ctccctgcct ccctgacttt gcaacaccgc gttccgggag gaccggcctc ggcgagggag      660

gaggcggggg agctgcgaac acccagaccc aaaccctgac atgctctggg gcggagagga      720

ggaagccagg agctgagcgc gccgcggggg ctgcttcgcc ctccggctcc gagcgccggg      780

ctccgggcgc cctgccctgc gcctgggcag cagccttgct ggtcttgggg gcgccccccg      840

cttcccgccc cgggggtccg cggccggcag gaccatgctg ctgaaagagt accggatctg      900

catgccgctc accgtagacg agtacaaaat tggacagctg tacatgatca gcaaacacag      960

ccatgaacag agtgaccggg gagaaggggt ggaggtcgtc cagaatgagc cctttgagga     1020

ccctcaccat ggcaatgggc agttcaccga gaagcgggtg tatctcaaca gcaaactgcc     1080

tagttgggct agagctgttg tccccaaaat attttatgtg acagagaagg cttggaacta     1140

ttatccctac acaattacag aatacacatg ttcctttctg ccgaaattct ccattcatat     1200

agaaaccaag tatgaggaca acaaaggaag caatgacacc attttcgaca atgaagccaa     1260

agacgtggag agagaagttt gctttattga tattgcctgc gatgaaattc cagagcgcta     1320

ctacaaagaa tctgaggatc ctaagcactt caagtcagag aagacaggac ggggacagtt     1380

gagggaaggc tggagagata gtcatcagcc tatcatgtgc tcctacaagc tggtgactgt     1440

gaagtttgag gtctgggggc ttcagaccag agtggaacaa tttgtacaca aggtggtccg     1500

agacattctg ctgattggac atagacaggc ttttgcatgg gttgatgagt ggtatgatat     1560

gacaatggat gatgttcggg aatacgagaa aaacatgcat gaacaaacca acataaaagt     1620

ttgcaatcag cattcctccc ctgtggatga catagagagt catgcccaaa caagtacatg     1680

acaatggatg aagtccgaga atttgaacga gccactcagg aagccaccaa caagaaaatc     1740

ggcattttcc cacctgcaat ttctatctcc agcatccccc tgctgccttc ttccgtccgc     1800

agtgcgcctt ctagtgctcc atccacccct ctctccacag acgcacccga atttctgtcc     1860

gttcccaaag atcggccccg gaaaaagtct gccccagaaa ctctcacact tccagaccct     1920

gagaaaaaag ccaccctgaa tttacccggc atgcactctt cagataagcc atgtcggccc     1980

aaatctgagt aactttatat aaatatctca tggggtttta tattttcatt tgttgttgtt     2040

gttttttttt aagaatcttc tgatagagaa aaagactgct ttgtcactca aacatgttcc     2100

ttcgaccttt cagtgtgcat gtgactcagt aacttcacat agaatatgat tccctaagta     2160

tgctacacag catcatatta gatgtaagat gtaagacttg caaaggacag aaggaatctt     2220

ctgtaaccac atagctgtat gccagagagg aagccttgtt attgggcatt tgatgaggtt     2280

tggcatggac ttcaaggata aatgaatgaa aactttgcac cacttttgtt acaaggtacg     2340

gtagaaaata gtgaagtcag tttcctctca tcaaatctaa aattctccaa aatactctca     2400

ggcataacat acttagctgt taaattttga actgctaatt actaatactt gaataccaat     2460

agttactgag attcctattt tgtggttagt ctgactcagg atttggagcc taattaactc     2520

taaacttttg aaaattttaa tcatcaagct atagaggctc caagtgcaat taataataac     2580

tcatttatac cttccacaga atttaataaa gattctactt gtttctgtct tttaataact     2640

ttcccctttt gtgcccttgt ggcctcagaa atccttaaga attgcatgga tgaatgtgac     2700

cataactgat tttggaatgg ttcagtttag gaaccaagag gcccaggtga ggcaacatct     2760

tttttctcta caggtaccaa caaaccttga cttgtcagct tccatcatca attaagattc     2820

tcagaatttg caattaattg aatagaattc atttactatc tgcccactca aagaagtaca     2880

agggtagagt aagctaactg ggctttaaca tggtcagaat gtctggtgca tgaactataa     2940

aaaagagaac tgtctcccat ccccttcctt gttttactct tagtaacatc cagaattccc     3000

tggaacagat tgcctaccac cagaccttag aaaagactgt cattctcttg ctccttactt     3060

gaaatacaaa tattgggaat gtcacagaca tcaagcaact actgtcaagt gggaggagag     3120

aatgagcaga attgctgact cctatttgta gagtgaaaag gaggagtgat aatagatgcc     3180

cttctgtcta gctttccttt cttcaactag tggtaatgca agattagaat caaggttgac     3240

aggaggcaag gtcactcact gaagtgacag aaagacaatt ctcctttgct ccaaagagag     3300

aaatctgtca cctttgcacc tcactgcctt taaacacaga cgggagggca ggccaaatct     3360

cagcattgac ttttgtcctc caagagagga agagaagaag taattgggca acttggaggc     3420

ccacgcccca gctagccttc ctgatcgtaa cctccaacct caggaaaggg accttcccaa     3480

aacacagatc ccaaaggaaa caaaatagac caaggagcat aatctgcttc tctcacacag     3540

cctctctgcc agtggaccct gcctgcttcc ctctcagtgc tcagcactct gtgtagtgtc     3600

tttcaggttg atacactctc ccaaggtgca ggcgctggcc ccatgagccc agcaccaaag     3660

ttttctaagt cataggtcag actgtcaaga tcatttcttt atctataggt tgatatttag     3720

cttaaaaaaa aagaataaac ctagaactca aaggaaacct gttgcaaata gcttagatca     3780

acagtgtatc tcttccctaa gaatgatagt atcttagtaa gacaccttct atgcatggta     3840

tggaagcatg atttttgctt gtgggaaaac ctaatatttt atcagacccc tcggacttct     3900

caatccctcc ctctccacac agtagtactt aatgaaaatg ttttgcttta gagagcaaaa     3960

tgctactttc agaagacact gaaatagtat atgtatttgc ttaccatttg caagctaaaa     4020

tcaaggtggg atggggtcat tattttcaca tagaatgtat ttattttgtg caggctgtta     4080

aacacatctg gcacctagtt tttccattaa gagcattgct attttccctt tttataaagt     4140

agcttctgct gtcaaggtta acaattctat atgctttagg aagctaagtt ctaatttcct     4200

tttgtgagtt tcatttcttt tataaccagt atgttaccac agacatcagt tgcaaagcta     4260

cgatgatagt gtgattctta gccgaaaaaa aagcgtgtgc tcttaaagta tgttcagttt     4320

ttctgtctac atatgctttg tgtgagttaa aaagggggtg ggtggtgtaa atattccttt     4380

agctgctttg catatttaac ccagtcatca aaaggcataa atgacttcaa tattttatat     4440

atcttggttt tcaagtatca tttcacattc tctatacatg actttgttat tgtggaatac     4500

aagcctgcaa tggatgtata tatacagaac attaataatt cttagaagga tggaagccaa     4560

atggctgcat gatggaaatt agaagaaaaa aaaagcagaa acttgaattt gctaagcatg     4620

tttgggggga aatagaatcc ttaactcagt gcctctgtct gcgatatgga aaccttcaac     4680

tttgttcacc aaaattgtat tatacctgtg tatatatata tatatatata tatataaata     4740

taaatatagt atagtgaatc agacaccatc agttttaagt ctctggtagc caaacttaaa     4800

taaataatcc atagaatatc acatacgttc actccatctt catctctgaa gttagtggag     4860

accatcaaaa tgactgtaca tttcataact ctgggaagat ttcaaatgtg aagtgcccct     4920

gtgcattttc ttggccatag cacggcattc ttgctttagc tgtgctttcc tgggatgaga     4980

agatcttggt gtatttaaca cataagcttt gttagaaatc acctctgaag atcatttcat     5040

tttctcactt tgggttgttg caagacaaag caaaggaaaa ggaacacaat gaaggaggcc     5100

gtgacatttt tagttgccac cgttgtaact caaacaatat gggtttgttg gtgaactgat     5160

ttatcaaggc ttctgttacg gttttgcatc tgtgtgtgag gaaaatttta atttatttgg     5220

aagtatttat tagccatgtt gttggtcctg aaaataaatc tctaagtagc acagttgtgg     5280

gtatattatg cagacactta ccacaatacc tgcaaaagta actgtggttt tctttcaaga     5340

cactgtaata aacagtgaac taagagaata gattctgata catctcgata aatcattctc     5400

tgcaaaagtt tcagggctaa tgtatttatg tgtattttta aattctactt tctttggcat     5460

ctcttcatgg ctcagcgaca acaaagtaat aggtcattgg ctggcttacg tcgataggaa     5520

ttttactctt aagaagggcc agtgtatagc tgactctaca tataatgtgt aatcagataa     5580

tccaatagag aggaattgtc caaatagttt tagtaccttt ctgatcatct gactcagtag     5640

gctaggagac aatctgtcat ctgagccata gttcttgaga tttaaaaagt ctgtccagtg     5700

actgcaatct gattatgaat aaactatttt aactattcat tcttgctgaa actgaagtgt     5760

acacaatagc acactgttgg catgctgagg caaaacattg ggttcttttg tgttctacct     5820

tcaaaacaat ctgtttgcat ttgaaatata agtgtttaag ctttttagga gttagtgtaa     5880

taagagaatg tgaatatgtt gggaaatttt cagatgccat taataattgt aattttgttg     5940

ttaaattaac aaggacttta ggataagcct cttgatgttt tttgctttaa attgaaagca     6000

tgtctgtcaa attgcaagtc tcccttcagt ttctatatat cacccaggag agggtctctg     6060

agttggtgtt gtacctgtac cactcacatg tagctcaagt gtaatttgta gtgtttacat     6120

tcaagctggg atcttgattg gttaaattaa tccacatacc actgccactg ctgaaggacc     6180

aggtgttgga atacacagca ttacagacta taagcaaagc aaacaaaagt tgatccttac     6240

atatgccatc cttctgtgtc attttgtggc tgttctgtgt ttttcttcct agttatttat     6300

tattgttaat aacttacttt ttcttacatt ctgttgtaaa taaaatacaa agcaatcttc     6360

tttgcaaaaa aaaaaaaaaa aaa                                             6383


<210>  554
<211>  6264
<212>  DNA
<213>  homo sapiens

<400>  554
cccgcaccca cctcccggcc ccaggcacac tgcatcggcg cggacgctcc ggccccggcg       60

aggtggctgc aaactcgcgg gcacgcacgg cgcccgggga gccgagggac tcgggggagg      120

ggacgcgcgc ggaaggcgcc agcttcctcc cgcccgcccc tggcagccgc gagccgaggt      180

tggaggcgcc cggggcccca gccgggcaga gccgagcggc ggcggcggcg gcggcttccc      240

ttttctcccc gagccgagcc ccggagcggc gcggggaccg gccctaaaaa gagcaggaaa      300

tcttgtttac cgcccgcgga gagaagccga tcgagccttt gtctggaaag tcagcatctc      360

cggctccggc tgcaatgtgt tcctggtgac attagcatcg ggcagacccg ccggaggagg      420

ggggtcgcca ggttcccgtc tgctttcgga ggcggatcga gcgggtgact tttgtgcatt      480

cgttttaatt tttggaaatc tctctttttt cctccctcgc tcgctgccgg gcatgtcctg      540

atctggcggc cgctcctacc accctgggca gccgagcaga gtcgtcccca gcgggtctcc      600

ctccctgcct ccctgacttt gcaacaccgc gttccgggag gaccggcctc ggcgagggag      660

gaggcggggg agctgcgaac acccagaccc aaaccctgac atgctctggg gcggagagga      720

ggaagccagg agctgagcgc gccgcggggg ctgcttcgcc ctccggctcc gagcgccggg      780

ctccgggcgc cctgccctgc gcctgggcag cagccttgct ggtcttgggg gcgccccccg      840

cttcccgccc cgggggtccg cggccggcag gaccatgctg ctgaaagagt accggatctg      900

catgccgctc accgtagacg agtacaaaat tggacagctg tacatgatca gcaaacacag      960

ccatgaacag agtgaccggg gagaaggggt ggaggtcgtc cagaatgagc cctttgagga     1020

ccctcaccat ggcaatgggc agttcaccga gaagcgggtg tatctcaaca gcaaactgcc     1080

tagttgggct agagctgttg tccccaaaat attttatgtg acagagaagg cttggaacta     1140

ttatccctac acaattacag aatacacatg ttcctttctg ccgaaattct ccattcatat     1200

agaaaccaag tatgaggaca acaaaggaag caatgacacc attttcgaca atgaagccaa     1260

agacgtggag agagaagttt gctttattga tattgcctgc gatgaaattc cagagcgcta     1320

ctacaaagaa tctgaggatc ctaagcactt caagtcagag aagacaggac ggggacagtt     1380

gagggaaggc tggagagata gtcatcagcc tatcatgtgc tcctacaagc tggtgactgt     1440

gaagtttgag gtctgggggc ttcagaccag agtggaacaa tttgtacaca aggtggtccg     1500

agacattctg ctgattggac atagacaggc ttttgcatgg gttgatgagt ggtatgacat     1560

gacaatggat gaagtccgag aatttgaacg agccactcag gaagccacca acaagaaaat     1620

cggcattttc ccacctgcaa tttctatctc cagcatcccc ctgctgcctt cttccgtccg     1680

cagtgcgcct tctagtgctc catccacccc tctctccaca gacgcacccg aatttctgtc     1740

cgttcccaaa gatcggcccc ggaaaaagtc tgccccagaa actctcacac ttccagaccc     1800

tgagaaaaaa gccaccctga atttacccgg catgcactct tcagataagc catgtcggcc     1860

caaatctgag taactttata taaatatctc atggggtttt atattttcat ttgttgttgt     1920

tgtttttttt taagaatctt ctgatagaga aaaagactgc tttgtcactc aaacatgttc     1980

cttcgacctt tcagtgtgca tgtgactcag taacttcaca tagaatatga ttccctaagt     2040

atgctacaca gcatcatatt agatgtaaga tgtaagactt gcaaaggaca gaaggaatct     2100

tctgtaacca catagctgta tgccagagag gaagccttgt tattgggcat ttgatgaggt     2160

ttggcatgga cttcaaggat aaatgaatga aaactttgca ccacttttgt tacaaggtac     2220

ggtagaaaat agtgaagtca gtttcctctc atcaaatcta aaattctcca aaatactctc     2280

aggcataaca tacttagctg ttaaattttg aactgctaat tactaatact tgaataccaa     2340

tagttactga gattcctatt ttgtggttag tctgactcag gatttggagc ctaattaact     2400

ctaaactttt gaaaatttta atcatcaagc tatagaggct ccaagtgcaa ttaataataa     2460

ctcatttata ccttccacag aatttaataa agattctact tgtttctgtc ttttaataac     2520

tttccccttt tgtgcccttg tggcctcaga aatccttaag aattgcatgg atgaatgtga     2580

ccataactga ttttggaatg gttcagttta ggaaccaaga ggcccaggtg aggcaacatc     2640

ttttttctct acaggtacca acaaaccttg acttgtcagc ttccatcatc aattaagatt     2700

ctcagaattt gcaattaatt gaatagaatt catttactat ctgcccactc aaagaagtac     2760

aagggtagag taagctaact gggctttaac atggtcagaa tgtctggtgc atgaactata     2820

aaaaagagaa ctgtctccca tccccttcct tgttttactc ttagtaacat ccagaattcc     2880

ctggaacaga ttgcctacca ccagacctta gaaaagactg tcattctctt gctccttact     2940

tgaaatacaa atattgggaa tgtcacagac atcaagcaac tactgtcaag tgggaggaga     3000

gaatgagcag aattgctgac tcctatttgt agagtgaaaa ggaggagtga taatagatgc     3060

ccttctgtct agctttcctt tcttcaacta gtggtaatgc aagattagaa tcaaggttga     3120

caggaggcaa ggtcactcac tgaagtgaca gaaagacaat tctcctttgc tccaaagaga     3180

gaaatctgtc acctttgcac ctcactgcct ttaaacacag acgggagggc aggccaaatc     3240

tcagcattga cttttgtcct ccaagagagg aagagaagaa gtaattgggc aacttggagg     3300

cccacgcccc agctagcctt cctgatcgta acctccaacc tcaggaaagg gaccttccca     3360

aaacacagat cccaaaggaa acaaaataga ccaaggagca taatctgctt ctctcacaca     3420

gcctctctgc cagtggaccc tgcctgcttc cctctcagtg ctcagcactc tgtgtagtgt     3480

ctttcaggtt gatacactct cccaaggtgc aggcgctggc cccatgagcc cagcaccaaa     3540

gttttctaag tcataggtca gactgtcaag atcatttctt tatctatagg ttgatattta     3600

gcttaaaaaa aaagaataaa cctagaactc aaaggaaacc tgttgcaaat agcttagatc     3660

aacagtgtat ctcttcccta agaatgatag tatcttagta agacaccttc tatgcatggt     3720

atggaagcat gatttttgct tgtgggaaaa cctaatattt tatcagaccc ctcggacttc     3780

tcaatccctc cctctccaca cagtagtact taatgaaaat gttttgcttt agagagcaaa     3840

atgctacttt cagaagacac tgaaatagta tatgtatttg cttaccattt gcaagctaaa     3900

atcaaggtgg gatggggtca ttattttcac atagaatgta tttattttgt gcaggctgtt     3960

aaacacatct ggcacctagt ttttccatta agagcattgc tattttccct ttttataaag     4020

tagcttctgc tgtcaaggtt aacaattcta tatgctttag gaagctaagt tctaatttcc     4080

ttttgtgagt ttcatttctt ttataaccag tatgttacca cagacatcag ttgcaaagct     4140

acgatgatag tgtgattctt agccgaaaaa aaagcgtgtg ctcttaaagt atgttcagtt     4200

tttctgtcta catatgcttt gtgtgagtta aaaagggggt gggtggtgta aatattcctt     4260

tagctgcttt gcatatttaa cccagtcatc aaaaggcata aatgacttca atattttata     4320

tatcttggtt ttcaagtatc atttcacatt ctctatacat gactttgtta ttgtggaata     4380

caagcctgca atggatgtat atatacagaa cattaataat tcttagaagg atggaagcca     4440

aatggctgca tgatggaaat tagaagaaaa aaaaagcaga aacttgaatt tgctaagcat     4500

gtttgggggg aaatagaatc cttaactcag tgcctctgtc tgcgatatgg aaaccttcaa     4560

ctttgttcac caaaattgta ttatacctgt gtatatatat atatatatat atatataaat     4620

ataaatatag tatagtgaat cagacaccat cagttttaag tctctggtag ccaaacttaa     4680

ataaataatc catagaatat cacatacgtt cactccatct tcatctctga agttagtgga     4740

gaccatcaaa atgactgtac atttcataac tctgggaaga tttcaaatgt gaagtgcccc     4800

tgtgcatttt cttggccata gcacggcatt cttgctttag ctgtgctttc ctgggatgag     4860

aagatcttgg tgtatttaac acataagctt tgttagaaat cacctctgaa gatcatttca     4920

ttttctcact ttgggttgtt gcaagacaaa gcaaaggaaa aggaacacaa tgaaggaggc     4980

cgtgacattt ttagttgcca ccgttgtaac tcaaacaata tgggtttgtt ggtgaactga     5040

tttatcaagg cttctgttac ggttttgcat ctgtgtgtga ggaaaatttt aatttatttg     5100

gaagtattta ttagccatgt tgttggtcct gaaaataaat ctctaagtag cacagttgtg     5160

ggtatattat gcagacactt accacaatac ctgcaaaagt aactgtggtt ttctttcaag     5220

acactgtaat aaacagtgaa ctaagagaat agattctgat acatctcgat aaatcattct     5280

ctgcaaaagt ttcagggcta atgtatttat gtgtattttt aaattctact ttctttggca     5340

tctcttcatg gctcagcgac aacaaagtaa taggtcattg gctggcttac gtcgatagga     5400

attttactct taagaagggc cagtgtatag ctgactctac atataatgtg taatcagata     5460

atccaataga gaggaattgt ccaaatagtt ttagtacctt tctgatcatc tgactcagta     5520

ggctaggaga caatctgtca tctgagccat agttcttgag atttaaaaag tctgtccagt     5580

gactgcaatc tgattatgaa taaactattt taactattca ttcttgctga aactgaagtg     5640

tacacaatag cacactgttg gcatgctgag gcaaaacatt gggttctttt gtgttctacc     5700

ttcaaaacaa tctgtttgca tttgaaatat aagtgtttaa gctttttagg agttagtgta     5760

ataagagaat gtgaatatgt tgggaaattt tcagatgcca ttaataattg taattttgtt     5820

gttaaattaa caaggacttt aggataagcc tcttgatgtt ttttgcttta aattgaaagc     5880

atgtctgtca aattgcaagt ctcccttcag tttctatata tcacccagga gagggtctct     5940

gagttggtgt tgtacctgta ccactcacat gtagctcaag tgtaatttgt agtgtttaca     6000

ttcaagctgg gatcttgatt ggttaaatta atccacatac cactgccact gctgaaggac     6060

caggtgttgg aatacacagc attacagact ataagcaaag caaacaaaag ttgatcctta     6120

catatgccat ccttctgtgt cattttgtgg ctgttctgtg tttttcttcc tagttattta     6180

ttattgttaa taacttactt tttcttacat tctgttgtaa ataaaataca aagcaatctt     6240

ctttgcaaaa aaaaaaaaaa aaaa                                            6264


<210>  555
<211>  6383
<212>  DNA
<213>  homo sapiens

<400>  555
cccgcaccca cctcccggcc ccaggcacac tgcatcggcg cggacgctcc ggccccggcg       60

aggtggctgc aaactcgcgg gcacgcacgg cgcccgggga gccgagggac tcgggggagg      120

ggacgcgcgc ggaaggcgcc agcttcctcc cgcccgcccc tggcagccgc gagccgaggt      180

tggaggcgcc cggggcccca gccgggcaga gccgagcggc ggcggcggcg gcggcttccc      240

ttttctcccc gagccgagcc ccggagcggc gcggggaccg gccctaaaaa gagcaggaaa      300

tcttgtttac cgcccgcgga gagaagccga tcgagccttt gtctggaaag tcagcatctc      360

cggctccggc tgcaatgtgt tcctggtgac attagcatcg ggcagacccg ccggaggagg      420

ggggtcgcca ggttcccgtc tgctttcgga ggcggatcga gcgggtgact tttgtgcatt      480

cgttttaatt tttggaaatc tctctttttt cctccctcgc tcgctgccgg gcatgtcctg      540

atctggcggc cgctcctacc accctgggca gccgagcaga gtcgtcccca gcgggtctcc      600

ctccctgcct ccctgacttt gcaacaccgc gttccgggag gaccggcctc ggcgagggag      660

gaggcggggg agctgcgaac acccagaccc aaaccctgac atgctctggg gcggagagga      720

ggaagccagg agctgagcgc gccgcggggg ctgcttcgcc ctccggctcc gagcgccggg      780

ctccgggcgc cctgccctgc gcctgggcag cagccttgct ggtcttgggg gcgccccccg      840

cttcccgccc cgggggtccg cggccggcag gaccatgctg ctgaaagagt accggatctg      900

catgccgctc accgtagacg agtacaaaat tggacagctg tacatgatca gcaaacacag      960

ccatgaacag agtgaccggg gagaaggggt ggaggtcgtc cagaatgagc cctttgagga     1020

ccctcaccat ggcaatgggc agttcaccga gaagcgggtg tatctcaaca gcaaactgcc     1080

tagttgggct agagctgttg tccccaaaat attttatgtg acagagaagg cttggaacta     1140

ttatccctac acaattacag aatacacatg ttcctttctg ccgaaattct ccattcatat     1200

agaaaccaag tatgaggaca acaaaggaag caatgacacc attttcgaca atgaagccaa     1260

agacgtggag agagaagttt gctttattga tattgcctgc gatgaaattc cagagcgcta     1320

ctacaaagaa tctgaggatc ctaagcactt caagtcagag aagacaggac ggggacagtt     1380

gagggaaggc tggagagata gtcatcagcc tatcatgtgc tcctacaagc tggtgactgt     1440

gaagtttgag gtctgggggc ttcagaccag agtggaacaa tttgtacaca aggtggtccg     1500

agacattctg ctgattggac atagacaggc ttttgcatgg gttgatgagt ggtatgatat     1560

gacaatggat gatgttcggg aatacgagaa aaacatgcat gaacaaacca acataaaagt     1620

ttgcaatcag cattcctccc ctgtggatga catagagagt catgcccaaa caagtacatg     1680

acaatggatg aagtccgaga atttgaacga gccactcagg aagccaccaa caagaaaatc     1740

ggcattttcc cacctgcaat ttctatctcc agcatccccc tgctgccttc ttccgtccgc     1800

agtgcgcctt ctagtgctcc atccacccct ctctccacag acgcacccga atttctgtcc     1860

gttcccaaag atcggccccg gaaaaagtct gccccagaaa ctctcacact tccagaccct     1920

gagaaaaaag ccaccctgaa tttacccggc atgcactctt cagataagcc atgtcggccc     1980

aaatctgagt aactttatat aaatatctca tggggtttta tattttcatt tgttgttgtt     2040

gttttttttt aagaatcttc tgatagagaa aaagactgct ttgtcactca aacatgttcc     2100

ttcgaccttt cagtgtgcat gtgactcagt aacttcacat agaatatgat tccctaagta     2160

tgctacacag catcatatta gatgtaagat gtaagacttg caaaggacag aaggaatctt     2220

ctgtaaccac atagctgtat gccagagagg aagccttgtt attgggcatt tgatgaggtt     2280

tggcatggac ttcaaggata aatgaatgaa aactttgcac cacttttgtt acaaggtacg     2340

gtagaaaata gtgaagtcag tttcctctca tcaaatctaa aattctccaa aatactctca     2400

ggcataacat acttagctgt taaattttga actgctaatt actaatactt gaataccaat     2460

agttactgag attcctattt tgtggttagt ctgactcagg atttggagcc taattaactc     2520

taaacttttg aaaattttaa tcatcaagct atagaggctc caagtgcaat taataataac     2580

tcatttatac cttccacaga atttaataaa gattctactt gtttctgtct tttaataact     2640

ttcccctttt gtgcccttgt ggcctcagaa atccttaaga attgcatgga tgaatgtgac     2700

cataactgat tttggaatgg ttcagtttag gaaccaagag gcccaggtga ggcaacatct     2760

tttttctcta caggtaccaa caaaccttga cttgtcagct tccatcatca attaagattc     2820

tcagaatttg caattaattg aatagaattc atttactatc tgcccactca aagaagtaca     2880

agggtagagt aagctaactg ggctttaaca tggtcagaat gtctggtgca tgaactataa     2940

aaaagagaac tgtctcccat ccccttcctt gttttactct tagtaacatc cagaattccc     3000

tggaacagat tgcctaccac cagaccttag aaaagactgt cattctcttg ctccttactt     3060

gaaatacaaa tattgggaat gtcacagaca tcaagcaact actgtcaagt gggaggagag     3120

aatgagcaga attgctgact cctatttgta gagtgaaaag gaggagtgat aatagatgcc     3180

cttctgtcta gctttccttt cttcaactag tggtaatgca agattagaat caaggttgac     3240

aggaggcaag gtcactcact gaagtgacag aaagacaatt ctcctttgct ccaaagagag     3300

aaatctgtca cctttgcacc tcactgcctt taaacacaga cgggagggca ggccaaatct     3360

cagcattgac ttttgtcctc caagagagga agagaagaag taattgggca acttggaggc     3420

ccacgcccca gctagccttc ctgatcgtaa cctccaacct caggaaaggg accttcccaa     3480

aacacagatc ccaaaggaaa caaaatagac caaggagcat aatctgcttc tctcacacag     3540

cctctctgcc agtggaccct gcctgcttcc ctctcagtgc tcagcactct gtgtagtgtc     3600

tttcaggttg atacactctc ccaaggtgca ggcgctggcc ccatgagccc agcaccaaag     3660

ttttctaagt cataggtcag actgtcaaga tcatttcttt atctataggt tgatatttag     3720

cttaaaaaaa aagaataaac ctagaactca aaggaaacct gttgcaaata gcttagatca     3780

acagtgtatc tcttccctaa gaatgatagt atcttagtaa gacaccttct atgcatggta     3840

tggaagcatg atttttgctt gtgggaaaac ctaatatttt atcagacccc tcggacttct     3900

caatccctcc ctctccacac agtagtactt aatgaaaatg ttttgcttta gagagcaaaa     3960

tgctactttc agaagacact gaaatagtat atgtatttgc ttaccatttg caagctaaaa     4020

tcaaggtggg atggggtcat tattttcaca tagaatgtat ttattttgtg caggctgtta     4080

aacacatctg gcacctagtt tttccattaa gagcattgct attttccctt tttataaagt     4140

agcttctgct gtcaaggtta acaattctat atgctttagg aagctaagtt ctaatttcct     4200

tttgtgagtt tcatttcttt tataaccagt atgttaccac agacatcagt tgcaaagcta     4260

cgatgatagt gtgattctta gccgaaaaaa aagcgtgtgc tcttaaagta tgttcagttt     4320

ttctgtctac atatgctttg tgtgagttaa aaagggggtg ggtggtgtaa atattccttt     4380

agctgctttg catatttaac ccagtcatca aaaggcataa atgacttcaa tattttatat     4440

atcttggttt tcaagtatca tttcacattc tctatacatg actttgttat tgtggaatac     4500

aagcctgcaa tggatgtata tatacagaac attaataatt cttagaagga tggaagccaa     4560

atggctgcat gatggaaatt agaagaaaaa aaaagcagaa acttgaattt gctaagcatg     4620

tttgggggga aatagaatcc ttaactcagt gcctctgtct gcgatatgga aaccttcaac     4680

tttgttcacc aaaattgtat tatacctgtg tatatatata tatatatata tatataaata     4740

taaatatagt atagtgaatc agacaccatc agttttaagt ctctggtagc caaacttaaa     4800

taaataatcc atagaatatc acatacgttc actccatctt catctctgaa gttagtggag     4860

accatcaaaa tgactgtaca tttcataact ctgggaagat ttcaaatgtg aagtgcccct     4920

gtgcattttc ttggccatag cacggcattc ttgctttagc tgtgctttcc tgggatgaga     4980

agatcttggt gtatttaaca cataagcttt gttagaaatc acctctgaag atcatttcat     5040

tttctcactt tgggttgttg caagacaaag caaaggaaaa ggaacacaat gaaggaggcc     5100

gtgacatttt tagttgccac cgttgtaact caaacaatat gggtttgttg gtgaactgat     5160

ttatcaaggc ttctgttacg gttttgcatc tgtgtgtgag gaaaatttta atttatttgg     5220

aagtatttat tagccatgtt gttggtcctg aaaataaatc tctaagtagc acagttgtgg     5280

gtatattatg cagacactta ccacaatacc tgcaaaagta actgtggttt tctttcaaga     5340

cactgtaata aacagtgaac taagagaata gattctgata catctcgata aatcattctc     5400

tgcaaaagtt tcagggctaa tgtatttatg tgtattttta aattctactt tctttggcat     5460

ctcttcatgg ctcagcgaca acaaagtaat aggtcattgg ctggcttacg tcgataggaa     5520

ttttactctt aagaagggcc agtgtatagc tgactctaca tataatgtgt aatcagataa     5580

tccaatagag aggaattgtc caaatagttt tagtaccttt ctgatcatct gactcagtag     5640

gctaggagac aatctgtcat ctgagccata gttcttgaga tttaaaaagt ctgtccagtg     5700

actgcaatct gattatgaat aaactatttt aactattcat tcttgctgaa actgaagtgt     5760

acacaatagc acactgttgg catgctgagg caaaacattg ggttcttttg tgttctacct     5820

tcaaaacaat ctgtttgcat ttgaaatata agtgtttaag ctttttagga gttagtgtaa     5880

taagagaatg tgaatatgtt gggaaatttt cagatgccat taataattgt aattttgttg     5940

ttaaattaac aaggacttta ggataagcct cttgatgttt tttgctttaa attgaaagca     6000

tgtctgtcaa attgcaagtc tcccttcagt ttctatatat cacccaggag agggtctctg     6060

agttggtgtt gtacctgtac cactcacatg tagctcaagt gtaatttgta gtgtttacat     6120

tcaagctggg atcttgattg gttaaattaa tccacatacc actgccactg ctgaaggacc     6180

aggtgttgga atacacagca ttacagacta taagcaaagc aaacaaaagt tgatccttac     6240

atatgccatc cttctgtgtc attttgtggc tgttctgtgt ttttcttcct agttatttat     6300

tattgttaat aacttacttt ttcttacatt ctgttgtaaa taaaatacaa agcaatcttc     6360

tttgcaaaaa aaaaaaaaaa aaa                                             6383


<210>  556
<211>  3730
<212>  DNA
<213>  homo sapiens

<400>  556
gtgtgaaggg ggggtccggg gggcgggtcc ctgtgccgct gacgtcccga gcagtgctgg       60

gaagtatagg ctgtgttgtc acgccggtgt cagtctgatg aagattggca tcaggtgaag      120

tctggagcag gacttctgag gctttctatc ctccatgctg ctcactagaa aaggggctgt      180

gaactgtgct ttggctctag cagacaggaa gaaattctgg cccagctgga agtagaaaga      240

ggggagtgag tctcctgagg accatctcag aggccccggg atcacccgaa cagtcctcca      300

tgtgaatcaa tcccatgatg caacatgcct ccccagcccc cgctctgacg atgatggcca      360

cgcagaatgt cccgccccca ccctaccagg acagcccaca gatgacggca accgcccagc      420

caccctccaa ggcccaggct gtccacatct ctgccccctc agctgctgcc agcacacctg      480

tgcccagtgc ccccatcgac ccccaggccc agctggaggc tgacaagcga gctgtataca      540

ggcaccctct tttcccgctc ctgacgctgc tgtttgagaa atgtgaacag gccacccagg      600

gctctgagtg catcacctcc gccagctttg atgtggacat cgagaacttt gtccaccagc      660

aggaacagga gcacaaaccc ttcttcagcg atgacccaga actggacaat ctgatggtga      720

aggcaatcca ggtcctgaga atccacctgc tggagctgga gaaagtcaat gaactctgca      780

aggacttttg taaccgttac atcacctgcc tcaaaaccaa gatgcacagc gacaacctgc      840

tcaggaatga tctagggggg ccctactccc ccaaccagcc ctccatcaac cttcactcac      900

aggacctcct gcagaattcc cccaattcca tgtccggagt ctccaataac ccccagggga      960

ttgtggtccc agcctcagcg ctccagcagg gcaacatcgc catgacaacc gtcaactcac     1020

aagttgtgtc aggtggagcc ttataccaac cggttaccat ggtaacctcc cagggtcagg     1080

tggtcaccca agcaatcccc cagggagcca tccagatcca gaacacacag gttaaccttg     1140

acctcacctc cctcctggac aatgaggata agaagtccaa gaacaaacga ggagtcttgc     1200

ccaagcatgc caccaatata atgcgttctt ggctcttcca gcatctcatg cacccctacc     1260

ccacggagga tgagaagagg cagatcgcag cccagaccaa cctcaccctc ctgcaagtaa     1320

acaactggtt catcaatgcc cggaggcgca tcctgcagcc catgcttgat gccagcaacc     1380

cagatcctgc ccccaaagcc aagaagatca agtctcagca ccggcccacc caaagattct     1440

ggcccaactc catcgctgcg ggggtgctgc agcagcaggg cggtgcccca gggacaaacc     1500

ccgatggttc catcaacttg gacaacctgc agtccctgtc ctcagacagt gccaccatgg     1560

ccatgcagca ggctatgatg gctgcacacg atgactcatt ggatgggaca gaagaagagg     1620

atgaggatga gatggaagag gaggaggagg aggagctgga ggaggaggtc gacgagctgc     1680

agacgacaaa tgtcagcgac ctgggcttgg aacacagtga ctccctggag tagtcgggca     1740

gcccagatgg cactgatcac tgagcaggag aggagtgtcg ccgggaggcc ttcagggtgg     1800

gggggaaggg gacatgggca ggaagcaccg agggagttgg gccctagctt ccccaaatca     1860

gtagcttgaa gaaaggcaaa ggagacacct gttccttccc aaccaccgag cttcaatgag     1920

gaccccagcc ccacttccct ggaactgccg aggactctgt ttggcggggc cagtcgagca     1980

gcctgtgtgg aaagacagga gtgagatctg gactcaccaa atccctgagg atagatggca     2040

cccatggccc ccacccacgg aaggacttga gttgtttaca agccctgcac tgaggcagat     2100

tggtgctgtt cgcagagtag gcctttgccc gggggcagac ttagaaggaa ggggagagac     2160

aaagggggac tgagtttcat ccccagaagt ttctcagctc ctttgacaga cattcaaggg     2220

caggagggag ccccaaagca taaccagtgg ccagaggagt gggagggcct gaggcatcac     2280

atcttgcaga tcagaatggg atggaatcca ccaggctcca gctcatccct ccaaggccct     2340

gtctctgcgc acagcaacca tggacatggg agaaagggat gggagccaca gtgcccttca     2400

ctctctcctg gaaaccaact gtaagctggt gggctcaacc tgtgggaggt taagaggagt     2460

cccttctggg ttgactccaa gagccaagga gatggcagac cctgggctag gaaccatatg     2520

gaggtgactt tgaggccaca gctgtcccta ggtgatcaca gaacttagct cctttaacaa     2580

caggacaatg gttttttacc ctagatgttc ccaccttcag tgctccacgc cctccataga     2640

ccttcagaga aggtgaaacc aggttatctg ggaatctttc cagcccgcag gtcgccacgg     2700

ccatcccttt gctcccagcc tggctccatc agcctccagc ttcctttctt cattctgtcc     2760

ttcagggaag gcagaagaaa cattggaaag catctagtcc agtgggaagc caggggttgg     2820

agaaggtgct acatccctct tcccatcaat atcctaaatg tgggggaggg cccagagaat     2880

ggcacccaag agcctgcggg gatgcccatc ccacacaccc cacccagctg ttctaaccct     2940

gctatccaca gccctggagg aactggggct cctggaagga ggaggaggct ctccactgtc     3000

caccctaaca cataccctcc cacccacctt ccagaccccc ttggttggca ccctctcctc     3060

cggttccctc tcaccccatg gctgtgaatg acaggacagg tcacacgtgt gttttccatt     3120

gggtttaatt taatggacgt gcagtttcat ttgtaaattg tgcattggcc acctccttca     3180

gtggcaggat gtgagtggct acctggctca actggagggg accccttggg ccctctgggg     3240

cttcccctcc cccacctggt tggggtagag caaaaggatg gtcactcttc cgaggtctcc     3300

ctgaaatgaa tgtatttctc ccccaaaaga gctgatattt aatgttttaa taaggatttt     3360

tgagaaacaa ataaccttat ttataatctg ggtgatccaa tcatttttta ctcccttttg     3420

atgccataca tagaggaaag tctagctttt ttggcgtgag acttttgcaa tgtgcagtgg     3480

gataaaatgc atttcctttt ctggttcgtt tttcttgtta acacgcgcac acagacacac     3540

acacacaccg ttccactcac cacctggaca ggcgtccccc agcacggaca cactggcaca     3600

caggtgccca catctcttcc tctcagcccc tccacctgcc taatgttatg caacctcctt     3660

ctgatgtatc caccaaacca gtactgaatg tggccgagac gttttcagta aatcttatta     3720

cctaccgtaa                                                            3730


<210>  557
<211>  3730
<212>  DNA
<213>  homo sapiens

<400>  557
gtgtgaaggg ggggtccggg gggcgggtcc ctgtgccgct gacgtcccga gcagtgctgg       60

gaagtatagg ctgtgttgtc acgccggtgt cagtctgatg aagattggca tcaggtgaag      120

tctggagcag gacttctgag gctttctatc ctccatgctg ctcactagaa aaggggctgt      180

gaactgtgct ttggctctag cagacaggaa gaaattctgg cccagctgga agtagaaaga      240

ggggagtgag tctcctgagg accatctcag aggccccggg atcacccgaa cagtcctcca      300

tgtgaatcaa tcccatgatg caacatgcct ccccagcccc cgctctgacg atgatggcca      360

cgcagaatgt cccgccccca ccctaccagg acagcccaca gatgacggca accgcccagc      420

caccctccaa ggcccaggct gtccacatct ctgccccctc agctgctgcc agcacacctg      480

tgcccagtgc ccccatcgac ccccaggccc agctggaggc tgacaagcga gctgtataca      540

ggcaccctct tttcccgctc ctgacgctgc tgtttgagaa atgtgaacag gccacccagg      600

gctctgagtg catcacctcc gccagctttg atgtggacat cgagaacttt gtccaccagc      660

aggaacagga gcacaaaccc ttcttcagcg atgacccaga actggacaat ctgatggtga      720

aggcaatcca ggtcctgaga atccacctgc tggagctgga gaaagtcaat gaactctgca      780

aggacttttg taaccgttac atcacctgcc tcaaaaccaa gatgcacagc gacaacctgc      840

tcaggaatga tctagggggg ccctactccc ccaaccagcc ctccatcaac cttcactcac      900

aggacctcct gcagaattcc cccaattcca tgtccggagt ctccaataac ccccagggga      960

ttgtggtccc agcctcagcg ctccagcagg gcaacatcgc catgacaacc gtcaactcac     1020

aagttgtgtc aggtggagcc ttataccaac cggttaccat ggtaacctcc cagggtcagg     1080

tggtcaccca agcaatcccc cagggagcca tccagatcca gaacacacag gttaaccttg     1140

acctcacctc cctcctggac aatgaggata agaagtccaa gaacaaacga ggagtcttgc     1200

ccaagcatgc caccaatata atgcgttctt ggctcttcca gcatctcatg cacccctacc     1260

ccacggagga tgagaagagg cagatcgcag cccagaccaa cctcaccctc ctgcaagtaa     1320

acaactggtt catcaatgcc cggaggcgca tcctgcagcc catgcttgat gccagcaacc     1380

cagatcctgc ccccaaagcc aagaagatca agtctcagca ccggcccacc caaagattct     1440

ggcccaactc catcgctgcg ggggtgctgc agcagcaggg cggtgcccca gggacaaacc     1500

ccgatggttc catcaacttg gacaacctgc agtccctgtc ctcagacagt gccaccatgg     1560

ccatgcagca ggctatgatg gctgcacacg atgactcatt ggatgggaca gaagaagagg     1620

atgaggatga gatggaagag gaggaggagg aggagctgga ggaggaggtc gacgagctgc     1680

agacgacaaa tgtcagcgac ctgggcttgg aacacagtga ctccctggag tagtcgggca     1740

gcccagatgg cactgatcac tgagcaggag aggagtgtcg ccgggaggcc ttcagggtgg     1800

gggggaaggg gacatgggca ggaagcaccg agggagttgg gccctagctt ccccaaatca     1860

gtagcttgaa gaaaggcaaa ggagacacct gttccttccc aaccaccgag cttcaatgag     1920

gaccccagcc ccacttccct ggaactgccg aggactctgt ttggcggggc cagtcgagca     1980

gcctgtgtgg aaagacagga gtgagatctg gactcaccaa atccctgagg atagatggca     2040

cccatggccc ccacccacgg aaggacttga gttgtttaca agccctgcac tgaggcagat     2100

tggtgctgtt cgcagagtag gcctttgccc gggggcagac ttagaaggaa ggggagagac     2160

aaagggggac tgagtttcat ccccagaagt ttctcagctc ctttgacaga cattcaaggg     2220

caggagggag ccccaaagca taaccagtgg ccagaggagt gggagggcct gaggcatcac     2280

atcttgcaga tcagaatggg atggaatcca ccaggctcca gctcatccct ccaaggccct     2340

gtctctgcgc acagcaacca tggacatggg agaaagggat gggagccaca gtgcccttca     2400

ctctctcctg gaaaccaact gtaagctggt gggctcaacc tgtgggaggt taagaggagt     2460

cccttctggg ttgactccaa gagccaagga gatggcagac cctgggctag gaaccatatg     2520

gaggtgactt tgaggccaca gctgtcccta ggtgatcaca gaacttagct cctttaacaa     2580

caggacaatg gttttttacc ctagatgttc ccaccttcag tgctccacgc cctccataga     2640

ccttcagaga aggtgaaacc aggttatctg ggaatctttc cagcccgcag gtcgccacgg     2700

ccatcccttt gctcccagcc tggctccatc agcctccagc ttcctttctt cattctgtcc     2760

ttcagggaag gcagaagaaa cattggaaag catctagtcc agtgggaagc caggggttgg     2820

agaaggtgct acatccctct tcccatcaat atcctaaatg tgggggaggg cccagagaat     2880

ggcacccaag agcctgcggg gatgcccatc ccacacaccc cacccagctg ttctaaccct     2940

gctatccaca gccctggagg aactggggct cctggaagga ggaggaggct ctccactgtc     3000

caccctaaca cataccctcc cacccacctt ccagaccccc ttggttggca ccctctcctc     3060

cggttccctc tcaccccatg gctgtgaatg acaggacagg tcacacgtgt gttttccatt     3120

gggtttaatt taatggacgt gcagtttcat ttgtaaattg tgcattggcc acctccttca     3180

gtggcaggat gtgagtggct acctggctca actggagggg accccttggg ccctctgggg     3240

cttcccctcc cccacctggt tggggtagag caaaaggatg gtcactcttc cgaggtctcc     3300

ctgaaatgaa tgtatttctc ccccaaaaga gctgatattt aatgttttaa taaggatttt     3360

tgagaaacaa ataaccttat ttataatctg ggtgatccaa tcatttttta ctcccttttg     3420

atgccataca tagaggaaag tctagctttt ttggcgtgag acttttgcaa tgtgcagtgg     3480

gataaaatgc atttcctttt ctggttcgtt tttcttgtta acacgcgcac acagacacac     3540

acacacaccg ttccactcac cacctggaca ggcgtccccc agcacggaca cactggcaca     3600

caggtgccca catctcttcc tctcagcccc tccacctgcc taatgttatg caacctcctt     3660

ctgatgtatc caccaaacca gtactgaatg tggccgagac gttttcagta aatcttatta     3720

cctaccgtaa                                                            3730


<210>  558
<211>  7338
<212>  DNA
<213>  homo sapiens

<400>  558
agctgcaagt tgggctgcag gggcagcgca tacactacaa tggctgctgg aaagaggcgt       60

aaggaaacaa tttccaggcc cgccgcgtcc agcccgaaat atgagaaaaa aattattaga      120

aattccgcgg gcggtgtaga ggcggcggac gggccggagg gaggatgtta aagccccgcg      180

gttgcctctt ggtgctgcct tggccgtatt tggcacccag aatgcttcat tctgtgacgg      240

tctattaata aggttgcctt gctagagttt ggagcagggc ctcagattgg ccaaaatggg      300

aaggattgga ttccactctc ttccacgaag agtcaatggg actggctaag atcaaagtct      360

gaggcttttt ccatcagtaa tcagtccctt tttgctttct tttacgacca catgaaactt      420

gagaagccac ctaaagctat atcatttagt ggagttgggc agttcccaag tgtccaacaa      480

gaaggcctgg tttaggctgc gatggccact gtcattcctg gtgatttgtc agaagtaaga      540

gatacccaga aagtcccttc agggaaacgt aagcgtggtg aaaccaaacc aagaaaaaac      600

tttccttgcc aactgtgtga caaggccttt aacagtgttg agaaattaaa ggttcactcc      660

tactctcaca caggagagag gccctacaag tgcatacaac aagactgcac caaggccttt      720

gtttctaagt acaaattaca aaggcacatg gctactcatt ctcctgagaa aacccacaag      780

tgtaattatt gtgagaaaat gtttcaccgg aaagatcatc tgaagaatca cctccataca      840

cacgacccta acaaagagac gtttaagtgc gaagaatgtg gcaagaacta caataccaag      900

cttggattta aacgtcactt ggccttgcat gccgcaacaa gtggtgacct cacctgtaag      960

gtatgtttgc aaacttttga aagcacggga gtgcttctgg agcaccttaa atctcatgca     1020

ggcaagtcgt ctggtggggt taaagaaaaa aagcaccagt gcgaacattg tgatcgccgg     1080

ttctacaccc gaaaggatgt ccggagacac atggtggtgc acactggaag aaaggacttc     1140

ctctgtcagt attgtgcaca gagatttggg cgaaaggatc acctgactcg acatatgaag     1200

aagagtcaca atcaagagct tctgaaggtc aaaacagaac cagtggattt ccttgaccca     1260

tttacctgca atgtgtctgt gcctataaaa gacgagctcc ttccggtgat gtccttacct     1320

tccagtgaac tgttatcaaa gccattcaca aacactttgc agttaaacct ctacaacact     1380

ccatttcagt ccatgcagag ctcgggatct gcccaccaaa tgatcacaac tttacctttg     1440

ggaatgacat gcccaataga tatggacact gttcatccct ctcaccacct ttctttcaaa     1500

tatccgttca gttctacctc atatgcaatt tctattcctg aaaaagaaca gccattaaag     1560

ggggaaattg agagttacct gatggagtta caaggtggcg tgccctcttc atcccaagat     1620

tctcaagcat cgtcatcatc taagctaggg ttggatcctc agattgggtc cctagatgat     1680

ggtgcaggag acctctccct atccaaaagc tctatctcca tcagtgaccc cctaaacaca     1740

ccagcattgg atttttctca gttgtttaat ttcatacctt taaatggtcc tccctataat     1800

cctctatcag tggggagcct tggaatgagc tattcccagg aagaagcaca ttcttctgtt     1860

tcccagctcc ccccacaaac acaggatctt caggatcctg caaacactat agggcttggg     1920

tctctgcact cactgtcagc agctttcacc agcagtttaa gcacaagtac caccctccca     1980

cgtttccatc aagcttttca gtaggattct gggacatgga ttcattacag aaatgtatgt     2040

gtagctgtgc cctagatgac catttttatt ttagtgccta ctttaaaaca gtataaaaat     2100

ttctgctttt gtataataca aattttcatt aagccagtat aaaatagaaa ctagctttta     2160

aactgagctt tggaaccatt tgtgttcagt taagtttacc tgggtatttt gtcctgattc     2220

actgccaatt gtcacatttt aagacttttt tttttccata taggaaagcc attattagta     2280

gtaaactttt acaaatccca ttttcaaatt acttttagat cttaaaattt tcatttttgt     2340

ctaataacag tggctctacc ttttgacatc tggctcatta aaaaatttag caatagaatg     2400

taaattgtat aaaaagtttg tgaataactc aagggtttaa attttcttac tagcttctaa     2460

atggattaat aatcaagtgc ttcaaatgaa ttaagagtcc agtttcggaa gataataaat     2520

gtttgttaga tacaccataa tttcagatca gtatattctg aagactccct gttgtctggc     2580

taaaatattt gccatcttta ttatgagcct ttaaggaaaa caaaccctaa acacaaagca     2640

tcagtattta tagcaaaaag agactctgtt aggtgacatg gcatttcgtg tcacttaata     2700

gttggcccta aattagtaca caggatattt tgtcgtgttt catccttctt aacatgctat     2760

cttttcattt aataatagta atagtgtatg gcattggggt cttcagagtc gatatatagg     2820

tagatctctt tagtcttttc cacctttcac atccaagggg tgggtcaagt gcagccagca     2880

atttattttc attgttggcc cacggttagt ccataatcta gagccattgt ggaactgcag     2940

ccatgaggtg tgtttatccc acagtggatt gactcagcct ctgtgggtga cagacttcta     3000

agcaggaaga tagacgtgaa gcacatggtt acatttggga acttgtgtag ggatcatggc     3060

ccctgtagcc agggttaaaa actggacttt ttagaagtaa agtaaaagca tatcgcttat     3120

atcatttctt gctgaatttg atatgttttt ctttccctta agaatcaaaa gcagaaaaca     3180

aaaacaacag tcctactccg atgttatctt tctgattcaa tgtgaatcca tctttccttg     3240

caatattttg gatggagaat ttgaagttaa atgcattaga aaactacctg atgaactacc     3300

acaaagtttt aagtgactag aaatatatac agtaaaatcc cactttcatg catctctggg     3360

aaatgatagg agtattgcaa ataagttgag tttgtagagg gtaacaaagt aaagtaaaac     3420

aaacctatct tggttaacat gaaaataaca attgagaata tattatattc actgaataat     3480

tataggcttt tcctcacatt agacaaccaa cataatcttc ttaaaggtct aattaatata     3540

tttttctaag ggtcagttgg gacattaacc taagaaacat atctattaag cacttgttaa     3600

caccttattt taggaccctt tccgttgggg atgggggcaa gggtgggagg tttttagaag     3660

agtatatatc tctttaaaaa aaaacagaaa gaaaaatatt tctgagcact cattagccct     3720

atatggaaac ttctttcctt tttgtagggc cagttatcac tgcagattgc aatgtttacc     3780

aagaatttct aaaaatgagt gcagattact gaatataata cattatttaa aatatttggg     3840

agtagtataa tttgtggaga aatgtaaatt gtaataatgt aaatgggggc ttcaatatat     3900

atatataata cacacacaca cacacatgca cacataccgc acttcataga atcaaagttg     3960

ctctctgaag gagctttggc tcctgatatt ttatcatgct cctatatttt tttaatcctt     4020

ggagcagtag tttttatact tatgtattta aattttatta tgaaaaatta catttattaa     4080

aaaagtgtgt tccaaaggca ttaaaattat atatgttaat aaggaagtac atttttaaat     4140

ttttcaaact gctcctagct tttgattagg agaatatttt ttctgaaagt aggcttttcg     4200

ctctgcttca ttactgcttc ctttagtttc tatgaaacag attgcttacc taaatcttta     4260

gttgaatgat tagtgttcaa tattgcttta atcaccatat aaaaggaaaa aaattggtga     4320

cagagcacaa atagaaaacc tatttttaaa tagaaatcac aaatagcaag tgtggaagca     4380

ctactttatt ctgtttaaaa tgtacttaag aagtcatcaa attagtgaac tgagacattg     4440

gccttagtag gctgtattca ctgctaattt aaaaaaggga gtaccaggat ttattaagta     4500

aagcattttg gaaatgggga atagcgccat atatgtatgt atgtgtatgt gtgtgtgtgt     4560

gtgtgtatat atacacacac acacacatac ttaaatcttg ccctgcatga aattcaaata     4620

catggaggca catcttcagg gcaccagtgt taaaattttg gagtcttaat tttcatgtgt     4680

acacctcttt gcctgttccc acccccagac ttgaaataac acttcagagt aagagggaat     4740

tcagctaatt tgtttttaaa attgactgta gtggtcacta aacccttttt gagagaattt     4800

ctattaaaga tgaggcagac tcgcttattt gaattgcaca atgttctaac aaggatgtaa     4860

cacagaattg gctttttttt ccctagaaaa agattgtttg tttctatgtc aactagatat     4920

gattaaaaat aagtattgcc aatgctgttt tcattctcta gtggccagaa tcattatcct     4980

tgaaatttct ggtagtgcct tagcttggtt aaaaaaaaaa aaaaaaaaaa aaaaaaggga     5040

ttaacattaa ataaaagtag tttagaattt gggcctcaga caagatattg aacctcattc     5100

agtttcactt ccacatgtat gtacaagtta ggtcaccaaa cacggaagtg tgagtgtgga     5160

aggatcttgg cactgtaagc aatgctatcc attgatgtat acaagtacct ttatagttat     5220

cgatcactgt taaaactttc attttaaaat cctattacca agttcagttt tttaaaactt     5280

caattgtcct ggctgattat gcatcactct gtgtgcaact tttttatttc atttagtgtt     5340

tctttcaagc tgtgtatttt tgcctatttg ttgcttgtgc tttatttttc ttagtcattt     5400

gtggaatata gtgatatatt gtgttaattt ggacagtagc ggtttttaaa aaccatatac     5460

tgactgaaac atgagccaga gccgattgct ttattaagct aataatgaat gttaaagagt     5520

acatattttc aggatcgttc atctagtgag caatacacat attataggcc aatatttttt     5580

taaaaaatag agcttggtca acctctatac tacacatatt acaagatata gcactttcaa     5640

aatgaatcta aacctttaca gaaactttct tataggttat gccttttatt ttaagactta     5700

ttataattca agtgccatta gatgatatat atgtaggcct ttgatatata atgctttgtg     5760

tacaaaaatg gtagatggta ttttaaacag gtacattttt acagtgtttt cttatcaatt     5820

tgctatattg cacagaatca gtgtgtgtct tttcataagg ttttacaatg gtttattttt     5880

ttacaaggtt tacgtgtctc aaagcacact gtcttcccag tacgtaagtt aaaaaatacc     5940

agttcaccca agttgcttct agcctactga gatccatgtg acattggagg agatctttta     6000

aatgtttagt attcgtcatt agcaatggct ggctgttagt tctggtaaat gtgtgcctaa     6060

gttgaatttg tcttgttttt ctcacactgt gtcagcagcc atgtctacaa cacagataag     6120

tctgttgtga tcacatagat ctacataagt tgtgcagttt tgtgctaaaa acccataggg     6180

agctcctttg ggatcataga aaagaagatc atgcaaccag cattggtgaa ggcacactca     6240

gattgcactt agggcctttc tatgatgttg tcaaccctct gaggatggaa ggcagtgtct     6300

tttgatgtta tctagcctag aaatgacaca gaactattgc taatgtataa aacacttcat     6360

tatataagct tcagtggtac agatgaacca gaatgaatgt ttatcttctc agaaacactc     6420

cttcaatatt atattggatc atgctgctaa tgtaacttgg gctacaactc ttcatggtgc     6480

tacaaacttc tctgtctcat tcagtcgtat ttttttatcc atagaaaaag gactacatta     6540

ggtgtaaaag tgtacaatat atttttatac tgtgacttaa tttgtcatta acaaactttt     6600

acaccaccac aatgtattca tgtgcacttg caaaaggaga tctcggacat gcaaatgtta     6660

ccagaacaaa cccagctttt gtccacaagg tgactgtaac tcagaatgga aagtgggctt     6720

tataataggg tgtggagtga agaacatgct gtatgttact aacagccctt tgaatttaac     6780

aaaaactggg aatccattag gaaacggatt gcatcatacc tgaacataag ctggactgct     6840

gaaattgtat ttttagctaa tgaaaaagtg tttggactag tactctaaaa atgttctaat     6900

gataaagttt tgagtcaaaa tagaaaagaa aaaaatctgc attccaggcc gaattttgta     6960

tatttttatt gcatttaaaa ttgctattct gtaatattgg gaaatcaagt ggcttatcat     7020

gtatatcgtg tacttaaaat gtattcacaa actactgttg tatttgtata aaatatagac     7080

aaagatcata ttttttgtgt gtgtataagc tctgtaaaat agcaatcaca ttatgaagct     7140

gcagtgatac tacattttaa acattcacat ccaaagaagc agactattta ttgtccatat     7200

accagattta aaatattaat ttgctgctaa ttaaataata gtactgcagc ttcttgtggc     7260

ctacagtgtt atgtttgctg taagaataag atatgtgaat tccacaaaat atatgaataa     7320

aattatagaa tggcttta                                                   7338


<210>  559
<211>  2006
<212>  DNA
<213>  homo sapiens

<400>  559
ggcttgggca caagatggcc gctgcgcgcc cagaggccca gagtcggagc tcaccgactc       60

cggagtcgcg atcccaggag ccactggacc tggtcctggt gcctgatgac tgccggcctg      120

gcacaccccc gagtgacctc atcgagatcc aggtggtgaa ggtgacggac accacgctgg      180

tccctgagcc cccggagcca ggttctttcc actgtgcctt gtgccctgct gccttccggc      240

tggtttccga gctgctgttc cacgaacatg gccacttggc tggggccgag ggaggcgggc      300

agggtgggga cccgagccgg tgccacgtgt gcggccacag ctgcccgggc cccgccagcc      360

tgcgcgcgca ctacagcttg cacacggggg agcggcccta ccgctgcgcg ctctgccccc      420

gcgccttcaa ggccttggcg cccctgctcc ggcaccagca ccggcacggg gtggagccgg      480

gcacctctcg gaggcctccg gacacagcgg ccgttgcaga acagaggccc ggggtggccc      540

cggagagggc ggaggtggtg atggcggcgg cggcggcggg cgcagcggtg gggaagcctt      600

ttgcctgcag gttctgcgcc aagcccttcc gccgctcctc agacatgcga gaccacgagc      660

gcgtgcacac tggcgagcgg ccataccatt gcggcatctg cggcaagggc ttcacccagt      720

cctcggtgct tagcggccac gcccgcatcc acactggcga gcgcccgttc cgctgcacgc      780

tctgcgaccg caccttcaac aactcctcca acttccgcaa gcaccagcgc acccacttcc      840

acgggccggg gccggggctg ggagactctg gaggccagct gggctcgtcg gcggctgagg      900

ggtcggggag cgggtgtggg gtaggggacc ctgcggagga ggggcggggg gagaccgcga      960

aggtgaaggt ggaggccgac cagtaggctg cagaccaggg acatgggtta gttaaggcgg     1020

aggtacgagg ccgacccggg gagggggacg gggtggggaa acggaggcag gggacagaag     1080

aggggagatt gggggagaga tgacagctgc agggatggtt gtgagccgct agtgatggag     1140

agcagaggga gagggccagg ctccagactc ccacacgccc acacagcacc tctgccaggc     1200

ctaggagagg acaggtgcag ctcttgcagc tctgcgggtg tgcggccaaa ggcaaggccc     1260

acgggctgga tgtcacttcc ccgactgtct cttggttggc ttgtccttgt gcaagaccca     1320

gcctgtcacg acagagcctg ggcacttcag aggaggagcc aggatcgaat ggaagggggg     1380

aattggggtc caccatagtc ttctgctctg gtcctccacg ggtggaccag gatggagtct     1440

cctgcctacc tcactgcatt gcactggacc tgggatgcct atccaccctc tggcagaaga     1500

cactcaccag gttatctgtg aagagactct gggatcccat cacctcaaag ccagagggtc     1560

cccaagtcac cgctgagagc acttgagcct caaggatgta agcctgacca taggatcttg     1620

actccaacag cggcaacccc cacccccatt gtggtccgtc cttaacccat ccactcttct     1680

tcggaggcaa ctgagaacac ataaagcaag cagctaccta gcatccccct cctaaagctt     1740

tagactcaga gcccagggtc ccccacaagc ctcaaggtag cctcaggttt ctctaatttc     1800

ctccactccc agttcgaagc aaacagctta ctgcctagtc cccgccaatc ccaagggcgg     1860

gctggctgat ggcagcatgg tgggctggcc tgggtgtgga gtgaaagagt cactgtggtg     1920

ggggcgagag gaggacttgg gagctggagg tgtgacacct tcagttctgt tcctattaaa     1980

ggaccttctg aagggcaaaa aaaaaa                                          2006


<210>  560
<211>  2006
<212>  DNA
<213>  homo sapiens

<400>  560
ggcttgggca caagatggcc gctgcgcgcc cagaggccca gagtcggagc tcaccgactc       60

cggagtcgcg atcccaggag ccactggacc tggtcctggt gcctgatgac tgccggcctg      120

gcacaccccc gagtgacctc atcgagatcc aggtggtgaa ggtgacggac accacgctgg      180

tccctgagcc cccggagcca ggttctttcc actgtgcctt gtgccctgct gccttccggc      240

tggtttccga gctgctgttc cacgaacatg gccacttggc tggggccgag ggaggcgggc      300

agggtgggga cccgagccgg tgccacgtgt gcggccacag ctgcccgggc cccgccagcc      360

tgcgcgcgca ctacagcttg cacacggggg agcggcccta ccgctgcgcg ctctgccccc      420

gcgccttcaa ggccttggcg cccctgctcc ggcaccagca ccggcacggg gtggagccgg      480

gcacctctcg gaggcctccg gacacagcgg ccgttgcaga acagaggccc ggggtggccc      540

cggagagggc ggaggtggtg atggcggcgg cggcggcggg cgcagcggtg gggaagcctt      600

ttgcctgcag gttctgcgcc aagcccttcc gccgctcctc agacatgcga gaccacgagc      660

gcgtgcacac tggcgagcgg ccataccatt gcggcatctg cggcaagggc ttcacccagt      720

cctcggtgct tagcggccac gcccgcatcc acactggcga gcgcccgttc cgctgcacgc      780

tctgcgaccg caccttcaac aactcctcca acttccgcaa gcaccagcgc acccacttcc      840

acgggccggg gccggggctg ggagactctg gaggccagct gggctcgtcg gcggctgagg      900

ggtcggggag cgggtgtggg gtaggggacc ctgcggagga ggggcggggg gagaccgcga      960

aggtgaaggt ggaggccgac cagtaggctg cagaccaggg acatgggtta gttaaggcgg     1020

aggtacgagg ccgacccggg gagggggacg gggtggggaa acggaggcag gggacagaag     1080

aggggagatt gggggagaga tgacagctgc agggatggtt gtgagccgct agtgatggag     1140

agcagaggga gagggccagg ctccagactc ccacacgccc acacagcacc tctgccaggc     1200

ctaggagagg acaggtgcag ctcttgcagc tctgcgggtg tgcggccaaa ggcaaggccc     1260

acgggctgga tgtcacttcc ccgactgtct cttggttggc ttgtccttgt gcaagaccca     1320

gcctgtcacg acagagcctg ggcacttcag aggaggagcc aggatcgaat ggaagggggg     1380

aattggggtc caccatagtc ttctgctctg gtcctccacg ggtggaccag gatggagtct     1440

cctgcctacc tcactgcatt gcactggacc tgggatgcct atccaccctc tggcagaaga     1500

cactcaccag gttatctgtg aagagactct gggatcccat cacctcaaag ccagagggtc     1560

cccaagtcac cgctgagagc acttgagcct caaggatgta agcctgacca taggatcttg     1620

actccaacag cggcaacccc cacccccatt gtggtccgtc cttaacccat ccactcttct     1680

tcggaggcaa ctgagaacac ataaagcaag cagctaccta gcatccccct cctaaagctt     1740

tagactcaga gcccagggtc ccccacaagc ctcaaggtag cctcaggttt ctctaatttc     1800

ctccactccc agttcgaagc aaacagctta ctgcctagtc cccgccaatc ccaagggcgg     1860

gctggctgat ggcagcatgg tgggctggcc tgggtgtgga gtgaaagagt cactgtggtg     1920

ggggcgagag gaggacttgg gagctggagg tgtgacacct tcagttctgt tcctattaaa     1980

ggaccttctg aagggcaaaa aaaaaa                                          2006


<210>  561
<211>  2331
<212>  DNA
<213>  homo sapiens

<400>  561
ctttgtctct cgctgcagcc tgagctctag gtcttgtttt ccctgctttg tgttttctgc       60

tcgtggacgc ccagcctctg tggccctgtg gcctgcaggt attgggagat ccacagctaa      120

gacgccggga ccccctggaa gcctagaaat gggaccattg acatttaggg atgtggccat      180

agaattctct ctgaaggagt ggcaatgcct ggacactgca cagcggaatt tatatagaaa      240

tgtgatgtta gagaactaca gaaacctggt cttcctgggt attactgttt ctaagccaga      300

cctgatcact tgtctggagc aagggaaaga ggcctggagt atgaagagac atgagatcat      360

ggtggccaaa cccacagtta tgtgttctca ttttgcccaa gacctttggc cggagcagaa      420

tataaaagat tctttccaaa aagtgacact gaaaagatat ggaaaatgta gacatgaaaa      480

tttaccatta agaaaaggct gtgaaagtat ggatgagtgt aagatgcaca aaggaggttg      540

taatggactt aaccaatgtc tcacagctac ccagagcaaa atatttcaat gtgataaata      600

tgtaaaagtc gctcataaat tttcaaattc aaacagacat gagataagac atactaaaaa      660

gaaacctttc aaatgtacaa aatgtggcaa atcatttggc atgatttcat gcctaactga      720

acatagcaga attcatacta gagtaaattt ctacaaatgt gaagaatgtg gaaaagcctt      780

taactggtcc tcaaccctta ctaaacataa gagaattcat acgggagaga aaccttacaa      840

atgtgaagaa tgtggtaaag cctttaacca gtcctcaaac cttattaaac ataagaaaat      900

tcatactgga gagaaaccct acaaatgtga agaatgtggc aaaactttta accgattctc      960

aactcttact acccataaga taattcatac tggagagaaa ccctacaaat gtaaagaatg     1020

tggtaaagct tttaaccgat cttcaaccct tactacccat agaaaaattc atactggaga     1080

gaaaccttac aaatgtgaag aatgtggcaa agcctttaag cagtcctcaa accttactac     1140

acataagata attcatactg gagagaaacc ctacaaatgt aaaaaatgtg gaaaagcctt     1200

taaccagtct gcacacctta ccacacatga ggtaattcat actggagaga aaccctacaa     1260

atgtgaaaaa tgtggaaaag cctttaatca tttctcacac cttactacac ataagataat     1320

tcatactgga gagaaacctt acaaatgtaa agaatgtggt aaagctttta aacactcttc     1380

aacccttact aaacataaga taattcatac tggagagaag ccttacaaat gtaaagaatg     1440

tgaaaaagct tttaaccaat cctcaaaact tactgaacat aagaaaattc atactggaga     1500

gaaaccctat gaatgtgaaa aatgtggcaa agcttttaac cagtcctcaa atcttactag     1560

acataagaaa agtcatacag aagagaaacc ttacaaatgt gaagaatgtg gcaaaggttt     1620

taaatggccc tcaaccctta ctatccataa gataattcat actggagaga aaccatacaa     1680

atgtgaagaa tgtggcaaag cttttaacca atcctcaaaa cttaccaaac ataagaaaat     1740

tcatactgga gagaaaccct acacatgtga agaatgtggc aaagccttta accagtcctc     1800

aaaccttact aaacataaga gaattcatac tggagaaaaa ccttacaaat gtgaagaatg     1860

tgacaaagct tttaaatggt cctcagtcct tactaaacat aagataattc ataccggaga     1920

aaaattacaa atatgaaaat tatggcaaag ctttaatcaa tttacaagtc ttactaaaca     1980

taagaaaatt tatactggag agaaactact aacctgaaag atgtgacaat aattttgaca     2040

acacctcaga cttataaaag taatcatact ggtgagaaat tctaaaaatg tgaagactat     2100

ggcaaagtct ttaaatggtt gtcacacttt aggtaagata attcatattg gaacaaacta     2160

caagtgcaaa caatgtggca aaacttaatt tatgctcaca ccttactgca cagaaaagaa     2220

tttttagttg agaaaaagta tacaaatata aagaatgtgg aaaagccgtt aatatctgct     2280

cacatcttac tcagcatcag aaagtactta ataaaagcat tataaatgga a              2331


<210>  562
<211>  1290
<212>  DNA
<213>  homo sapiens

<400>  562
gagtctagtc tttgttcggg gctgtccaaa ggacgctagc tgttgcacct gttcctccct       60

gcgcgtaaga tagaggataa atctcctggc aaagcccaga atgaccacag ccctggaacc      120

tgaggaccaa aaaggacttc tgataattaa ggcagaggac cattactggg gacaggattc      180

cagctcacaa aagtgcagtc ctcacaggag ggaactctat agacaacact tcaggaagct      240

ctgctatcag gatgcacctg gaccccgtga agctcttacc cagctgtggg agctctgccg      300

tcagtggctg aggccagaat gccacaccaa ggagcagatt ttagacctgc tggtgctaga      360

acagttcctg agcattcttc ctaaagacct gcaagcatgg gtgcgtgcac accatccaga      420

gactggagag gaggcagtga cggtactgga ggatctggag agagagcttg atgaacctgg      480

aaagcaggtc ccaggcaatt cagaaagacg ggacatactc atggacaagt tggccccctt      540

gggaaggcca tatgaatcac tgactgtcca gctccatccc aaaaagaccc agctggagca      600

ggaagctggg aaaccacaaa ggaatggtga taaaactagg actaagaatg aagagttgtt      660

ccagaaggaa gatatgccca aagacaagga attccttggg gagataaatg acagactgaa      720

caaagatact cctcagcatc ctaagtccaa agatattatt gaaaatgagg gcagatcaga      780

atggcaacag agggaaagaa gacgatataa atgtgatgaa tgtgggaaaa gtttcagtca      840

tagctcagac cttagtaaac acaggagaac tcacacggga gagaagccct ataaatgtga      900

tgagtgtgga aaagccttca ttcagcgctc acatctcatt ggacatcata gagtacacac      960

gggagtaaaa ccctataaat gtaaagaatg tgggaaagac ttcagtgggc gcacaggtct     1020

tattcagcat cagagaatcc acacaggtga aaaaccctat gaatgtgatg agtgtggaag     1080

gcctttccga gtaagttcag ctcttattag acatcaaaga attcataccg caaataaact     1140

ctactaatat agcagtaata tcaaaagttc tttggacact caggcctaac tagttatcaa     1200

agaatctatt ttagaaacct tgagtttcct caatgtggtc aaagcttcag tcatcattaa     1260

acttctctgg accaaaaaaa aaaaaaaaaa                                      1290


<210>  563
<211>  1290
<212>  DNA
<213>  homo sapiens

<400>  563
gagtctagtc tttgttcggg gctgtccaaa ggacgctagc tgttgcacct gttcctccct       60

gcgcgtaaga tagaggataa atctcctggc aaagcccaga atgaccacag ccctggaacc      120

tgaggaccaa aaaggacttc tgataattaa ggcagaggac cattactggg gacaggattc      180

cagctcacaa aagtgcagtc ctcacaggag ggaactctat agacaacact tcaggaagct      240

ctgctatcag gatgcacctg gaccccgtga agctcttacc cagctgtggg agctctgccg      300

tcagtggctg aggccagaat gccacaccaa ggagcagatt ttagacctgc tggtgctaga      360

acagttcctg agcattcttc ctaaagacct gcaagcatgg gtgcgtgcac accatccaga      420

gactggagag gaggcagtga cggtactgga ggatctggag agagagcttg atgaacctgg      480

aaagcaggtc ccaggcaatt cagaaagacg ggacatactc atggacaagt tggccccctt      540

gggaaggcca tatgaatcac tgactgtcca gctccatccc aaaaagaccc agctggagca      600

ggaagctggg aaaccacaaa ggaatggtga taaaactagg actaagaatg aagagttgtt      660

ccagaaggaa gatatgccca aagacaagga attccttggg gagataaatg acagactgaa      720

caaagatact cctcagcatc ctaagtccaa agatattatt gaaaatgagg gcagatcaga      780

atggcaacag agggaaagaa gacgatataa atgtgatgaa tgtgggaaaa gtttcagtca      840

tagctcagac cttagtaaac acaggagaac tcacacggga gagaagccct ataaatgtga      900

tgagtgtgga aaagccttca ttcagcgctc acatctcatt ggacatcata gagtacacac      960

gggagtaaaa ccctataaat gtaaagaatg tgggaaagac ttcagtgggc gcacaggtct     1020

tattcagcat cagagaatcc acacaggtga aaaaccctat gaatgtgatg agtgtggaag     1080

gcctttccga gtaagttcag ctcttattag acatcaaaga attcataccg caaataaact     1140

ctactaatat agcagtaata tcaaaagttc tttggacact caggcctaac tagttatcaa     1200

agaatctatt ttagaaacct tgagtttcct caatgtggtc aaagcttcag tcatcattaa     1260

acttctctgg accaaaaaaa aaaaaaaaaa                                      1290


<210>  564
<211>  5823
<212>  DNA
<213>  homo sapiens

<400>  564
agttgccctg tcagtgcagg tggaggcccc ggcggggcaa agtggcagga acctcttaaa       60

gggcgagagc ggcgcggagc cagaacgcgg tcggcccggt ccccgccgca cccagcccag      120

agaagagttt agtgactgag gccgaaaatt cacagcacca acagaaggaa gagggtgagg      180

aagccataaa ctcaggccaa caagaacctc agcaggagga atcttgtcaa acagcagctg      240

aaggagataa ttggtgtgaa cagaagctga aagcttctaa tggagacact cctacacatg      300

aagacttgac caagaacaag gagcggacat cagaaagcag aggactttca cgactattct      360

cctcgtttct caaaaggccc aaatctcagg tgtccgagga agaaggcaaa gaagtagagt      420

cagataaaga aaaaggtgaa ggaggtcaga aagagataga atttggaacc agtcttgatg      480

aagagatcat tttaaaggcc ccaattgcag ctcctgaacc ggaactcaaa acagacccat      540

ctttggatct tcattcatta agcagtgcag aaacacagcc tcaccattac aattaagaat      600

tattttcaga gtcttcttat ttctgaagca tgtgaatatt atctgcatcg ttaaaagtcc      660

tgctcaggaa gaactcagag aagatccaga ttttgaaatt aaggaaggag aaggacttga      720

agagtgctcc aaaatagaag taaaagaaga aagccctcaa tcaaaagcag aaacagaatt      780

aaaagcttcc caaaaaccaa tcagaaaaca caggaacatg cactgcaagg tttctttgtt      840

ggatgacaca gtttatgaat gtgttgtgga gaaacatgct aagggacaag atttgcttaa      900

acgagtatgt gagcatctca atcttttgga agaagactat tttggtctag ccatttggga      960

taacgcaacc tctaagacat ggctggattc cgccaaagaa ataaaaaagc aggttcgtgg     1020

tgtcccttgg aattttacat ttaatgtaaa gttttatcca cctgacccag cacagttaac     1080

agaagacata acaagatatt atttatgtct tcagcttcgg caggacatag ttgcaggacg     1140

tctgccctgt tcctttgcaa ccttagcatt attaggttct tacaccatcc agtctgaact     1200

gggagactac gacccagaac tccatggcgt ggattatgtt agtgatttta aactggcccc     1260

gaatcagacc aaggaacttg aagagaaggt catggaactg cataagtcat acaggtccat     1320

gactccagct caggctgact tggagtttct tgagaatgcc aaaaagttgt ctatgtatgg     1380

agttgatctt cataaagcaa aggacttgga aggagtagat atcatcctag gtgtctgctc     1440

tagtggcctt ctggtttaca aagataagct gagaattaac cgcttccctt ggcccaaagt     1500

gctgaagatt tcttataaac gtagtagctt tttcatcaag attcggcctg gagagcaaga     1560

gcagtatgaa agtaccatcg gattcaaact tcccagttac cgagcagcta agaaattatg     1620

gaaagtctgt gtagaacatc acacgttttt cagattgaca tctacagaca ccattcccaa     1680

aagcaaattt cttgcgctag gatccaaatt tcgatacagt ggccggactc aagctcagac     1740

caggcaagct agtgctctaa ttgacaggcc tgccccacac ttcgagcgta cagcaagtaa     1800

acgggcgtcc cggagcctcg atggagcagc agctgtcgat tcggcagacc gaagtcctcg     1860

gcccacttct gcacctgcca ttactcaggg tcaggttgca gaaggtggcg tcctagatgc     1920

ctctgctaaa aaaacagtgg tccctaaagc acagaaggaa acagtgaagg ctgaagtgaa     1980

aaaggaagac gagccacctg agcaagctga gccagagccc acagaagcat ggaagaaaaa     2040

gagagaaaga ctagatggtg aaaacattta tatcagacat agcaatttaa tgttggagga     2100

tttagacaag agtcaagagg agatcaaaaa acatcatgcc agcatcagtg agctgaaaaa     2160

gaacttcatg gagtctgtac cagaaccacg gcctagtgaa tgggataaac gcttatccac     2220

tcactcaccc ttccgaactc ttaacatcaa tgggcaaatc cccacaggag aaggacctcc     2280

cctggtgaag acacaaactg tcaccatctc agataatgcc aatgctgtga aaagtgaaat     2340

cccaaccaaa gacgtcccta ttgtccacac tgagaccaag accatcactt atgaggctgc     2400

ccagactgta aaaggtggga tttcagagac acgtattgaa aagagaattg tgatcacagg     2460

agatgctgat attgaccatg atcaggtcct tgtacaagcc atcaaggagg caaaggagca     2520

gcacccagac atgtcagtga ccaaggtggt cgtccaccag gagaccgaga ttgctgatga     2580

gtgagctcag gaactaacct accccaactc tgcccttctc ccatccaaga gaaaccagca     2640

aaatgataaa gaagctaacc tgccatagtc agacttcaga ctttcaagat tattctaaat     2700

caccagaaaa ttaatttcag tttctattgg gagtttatac caagagattc ttctagatct     2760

cattgatcct tttgaagagc tttttctata ttaggatatc agaattgttc aacttttcac     2820

tctatagact gttttaagag ttttggggtt tttttaattg ggtggtttgt aaccccttca     2880

gcctagcctc tctgcccatt tatttccaac cccaacagac actgacaggg tccatggaat     2940

tcttcgggaa atcctccaag gactcttgtc agctgtgttg gaagccaaag ccagcttagt     3000

gggacttccg cgtctctccc tagtcttatc ccctttggat gatggcagaa acttcatgaa     3060

ccagcccttt ctcagagcca gtgatgtgag tgtatcagaa tgccagggag ggcaccagcc     3120

ctgatccaca gacctcggaa agatgcccct gttcctttgt tgcgggtggt tttggtaagg     3180

cagagccctc tgctgagaat gtagtattgt ttttcccctc tccctcctgc tttctttttg     3240

gagcttcttt gggtcaaaga catggaagtt gcttcagata tctgatactg tgaatgtttg     3300

aacatatccg tggccttcac ctctccagct acccttttac ctcatcagaa gcagtggctc     3360

agctaagtgc tccccctagc tcccatctca ggagaccaaa tctcacagaa aaataggcac     3420

tttgggccaa aagctctaat ggaacatttt tagtggtgat ttggggaagg aaagttaatg     3480

aggtttttaa aataaggttt tctagttttg agagtgtgca cttcacacag gggaatgggg     3540

ttacttctgt ctgatcctgg gcctttcttt catcccaaat gacaaggaat gtggctcaga     3600

gaagggtttt tcttttttga cctttcttct ctcaacagga acctgcctga ggacaccctt     3660

ctagagcaag gaattgactt ttaggagccg ttctccccac aagacaccac atgacaaggg     3720

gtataagccc cagccctgct cattcccact caccagctga ggtctgtcag gttttgaagg     3780

cttgattttg tggtgggttt ggggcttagt tttccttttt ttcattttga tttttgaaag     3840

tgaagatgat gccctaattc ctggtaagga tttggggcat agttttttgt ttttttgaga     3900

cggagtttcg ctcttgttgc ccaagctgga gtgcagtggc gcgatctcgg ctcactgcaa     3960

cctccgcctc ctgggttcaa gcagttctct tgcctcagcc tcccaagtag ctgggatgac     4020

aggcgcacac caccacgccc agcaaatttt ttgtattttt agtagaaacg ggatttcacc     4080

ttgttaggct ggtctcgaac tcctgacctc aggtgatcca cccaccttgg cctcccaaag     4140

tgctgggatt acaggtgtga gccaccacgc ccggccgatt tggggcattt ttatttaaca     4200

gaacttctct aaccttccaa ctgcttccca caaacacatt ggcctcaagg ctccttagaa     4260

tcccagttcc agcttcctaa aatagacagt gggtatcggg cagcagtcac tggggctcaa     4320

gggcagtgag caagagaaat gtctaaagct gcttctccca acaccgtcca aagtctccac     4380

tgcctgagtt ttgtttcggc tggtttgaac tcatttcggg tgtgtgcatt tttcttttgg     4440

tacccatgtg agacatgaac aacaggaggg agggaaagag cccaggtggg acgtgggaca     4500

ggcttagggg aaagagcttg tcctatctca ggaacaaaat tataggctgt gggcagaggg     4560

tctgaaaggt gggctttggg gtagtgccca agcctggtcg tgttgccagg agtggtgaca     4620

agaaatgcag cttacatcaa acgaacatgt agtgcatgcc cactgcctga tggccagatg     4680

gcctgtagga agagctacca gggcttccag acctgtggaa cgaagaggat ggggaaaagg     4740

cagagggcac tgagtgtccc tttaaaaact aacccactga atattccgtg tgatctagaa     4800

cagtgtggca gctttcacag cacaggaccg ttcatcgggg gcctaaacgt ttccctcagc     4860

tctgtcacca actcacttct ctcggcttcg ttgtctgtaa attggatgaa aagagctcta     4920

atgcctttca ggctcttaga agccatagat ttggacaagc ccagcaagat gggtgtcctt     4980

ccaggcctct tcccctttcc tccatctctg gcaacagttc ttggggtttg gcaattgttt     5040

ggattttttt tctttctgca gttgtgtgta tgtgtgtttg tgtgaagaaa aacagactct     5100

gtccaggtag aaatggtgag gagggggaag agaattacat ttccagggtc agaaacttgg     5160

caacagtttt cctagagtga ctcagacaca ccacagtaac aactctcgct gcaattttat     5220

tttaatttga gaaataaaga tttcctccaa gccacatgag gactctggca cccacccaca     5280

aagcaagacc tgtatttata agccgagggc tcagggagcc taactgcggg acccgtcagg     5340

gccccgtgac ccatccccgt ccccaccccc ccctccaccg ctgggcccat cagtgtgtgt     5400

tggggggatg cttggcagct gggggtgagg agacaacaaa cctcgggaac tggagccaga     5460

gctgcggcct gactgacgcc ttttgatgct cacgggaaat ttctgcccag gatctcagcc     5520

ccaggctggt tgtttctaca aatctctctc aaatgtatta ttttggtgac aaaaatgaag     5580

gagctttgta aatttttttt aaaattatga atcatatcaa gtagttgttt acatttcttg     5640

aaaaaatagg aactcgggca gcagaatcag attggcagaa tctttagact acacaggcaa     5700

taatcaagtc tgctgttttg gcctttcgta gtagaagtgg ttgtagtgtt tagatatctg     5760

tttggtcttg cttcttgtat tgcatttttt tcaataaaca acaacaaaaa gaactctcaa     5820

aaa                                                                   5823


<210>  565
<211>  5694
<212>  DNA
<213>  homo sapiens

<400>  565
agttgccctg tcagtgcagg tggaggcccc ggcggggcaa agtggcagga acctcttaaa       60

gggcgagagc ggcgcggagc cagaacgcgg tcggcccggt ccccgccgca cccagcccag      120

caacatcatg acaacagaga agagtttagt gactgaggcc gaaaattcac agcaccaaca      180

gaaggaagag ggtgaggaag ccataaactc aggccaacaa gaacctcagc aggaggaatc      240

ttgtcaaaca gcagctgaag gagataattg gtgtgaacag aagctgaaag cttctaatgg      300

agacactcct acacatgaag acttgaccaa gaacaaggag cggacatcag aaagcagagg      360

actttcacga ctattctcct cgtttctcaa aaggcccaaa tctcaggtgt ccgaggaaga      420

aggcaaagaa gtagagtcag ataaagaaaa aggtgaagga ggtcagaaag agatagaatt      480

tggaaccagt cttgatgaag agatcatttt aaaggcccca attgcagctc ctgaaccgga      540

actcaaaaca gacccatctt tggatcttca ttcattaagc agtgcagaaa cacagcctgc      600

tcaggaagaa ctcagagaag atccagattt tgaaattaag gaaggagaag gacttgaaga      660

gtgctccaaa atagaagtaa aagaagaaag ccctcaatca aaagcagaaa cagaattaaa      720

agcttcccaa aaaccaatca gaaaacacag gaacatgcac tgcaaggttt ctttgttgga      780

tgacacagtt tatgaatgtg ttgtggagac atggctggat tccgccaaag aaataaaaaa      840

gcaggttcgt ggtgtccctt ggaattttac atttaatgta aagttttatc cacctgaccc      900

agcacagtta acagaagaca taacaagata ttatttatgt cttcagcttc ggcaggacat      960

agttgcagga cgtctgccct gttcctttgc aaccttagca ttattaggtt cttacaccat     1020

ccagtctgaa ctgggagact acgacccaga actccatggc gtggattatg ttagtgattt     1080

taaactggcc ccgaatcaga ccaaggaact tgaagagaag gtcatggaac tgcataagtc     1140

atacaggtcc atgactccag ctcaggctga cttggagttt cttgagaatg ccaaaaagtt     1200

gtctatgtat ggagttgatc ttcataaagc aaaggacttg gaaggagtag atatcatcct     1260

aggtgtctgc tctagtggcc ttctggttta caaagataag ctgagaatta accgcttccc     1320

ttggcccaaa gtgctgaaga tttcttataa acgtagtagc tttttcatca agattcggcc     1380

tggagagcaa gagcagtatg aaagtaccat cggattcaaa cttcccagtt accgagcagc     1440

taagaaatta tggaaagtct gtgtagaaca tcacacgttt ttcagattga catctacaga     1500

caccattccc aaaagcaaat ttcttgcgct aggatccaaa tttcgataca gtggccggac     1560

tcaagctcag accaggcaag ctagtgctct aattgacagg cctgccccac acttcgagcg     1620

tacagcaagt aaacgggcgt cccggagcct cgatggagca gcagctgtcg attcggcaga     1680

ccgaagtcct cggcccactt ctgcacctgc cattactcag ggtcaggttg cagaaggtgg     1740

cgtcctagat gcctctgcta aaaaaacagt ggtccctaaa gcacagaagg aaacagtgaa     1800

ggctgaagtg aaaaaggaag acgagccacc tgagcaagct gagccagagc ccacagaagc     1860

atggaaggat ttagacaaga gtcaagagga gatcaaaaaa catcatgcca gcatcagtga     1920

gctgaaaaag aacttcatgg agtctgtacc agaaccacgg cctagtgaat gggataaacg     1980

cttatccact cactcaccct tccgaactct taacatcaat gggcaaatcc ccacaggaga     2040

aggacctccc ctggtgaaga cacaaactgt caccatctca gataatgcca atgctgtgaa     2100

aagtgaaatc ccaaccaaag acgtccctat tgtccacact gagaccaaga ccatcactta     2160

tgaggctgcc cagactgacg acaacagtgg agacttggac ccaggagtct tgctgacagc     2220

tcaaactatc acatctgaga ccccaagcag caccaccaca actcaaatta ccaagactgt     2280

aaaaggtggg atttcagaga cacgtattga aaagagaatt gtgatcacag gagatgctga     2340

tattgaccat gatcaggtcc ttgtacaagc catcaaggag gcaaaggagc agcacccaga     2400

catgtcagtg accaaggtgg tcgtccacca ggagaccgag attgctgatg agtgagctca     2460

ggaactaacc taccccaact ctgcccttct cccatccaag agaaaccagc aaaatgataa     2520

agaagctaac ctgccatagt cagacttcag actttcaaga ttattctaaa tcaccagaaa     2580

attaatttca gtttctattg ggagtttata ccaagagatt cttctagatc tcattgatcc     2640

ttttgaagag ctttttctat attaggatat cagaattgtt caacttttca ctctatagac     2700

tgttttaaga gttttggggt ttttttaatt gggtggtttg taaccccttc agcctagcct     2760

ctctgcccat ttatttccaa ccccaacaga cactgacagg gtccatggaa ttcttcggga     2820

aatcctccaa ggactcttgt cagctgtgtt ggaagccaaa gccagcttag tgggacttcc     2880

gcgtctctcc ctagtcttat cccctttgga tgatggcaga aacttcatga accagccctt     2940

tctcagagcc agtgatgtga gtgtatcaga atgccaggga gggcaccagc cctgatccac     3000

agacctcgga aagatgcccc tgttcctttg ttgcgggtgg ttttggtaag gcagagccct     3060

ctgctgagaa tgtagtattg tttttcccct ctccctcctg ctttcttttt ggagcttctt     3120

tgggtcaaag acatggaagt tgcttcagat atctgatact gtgaatgttt gaacatatcc     3180

gtggccttca cctctccagc taccctttta cctcatcaga agcagtggct cagctaagtg     3240

ctccccctag ctcccatctc aggagaccaa atctcacaga aaaataggca ctttgggcca     3300

aaagctctaa tggaacattt ttagtggtga tttggggaag gaaagttaat gaggttttta     3360

aaataaggtt ttctagtttt gagagtgtgc acttcacaca ggggaatggg gttacttctg     3420

tctgatcctg ggcctttctt tcatcccaaa tgacaaggaa tgtggctcag agaagggttt     3480

ttcttttttg acctttcttc tctcaacagg aacctgcctg aggacaccct tctagagcaa     3540

ggaattgact tttaggagcc gttctcccca caagacacca catgacaagg ggtataagcc     3600

ccagccctgc tcattcccac tcaccagctg aggtctgtca ggttttgaag gcttgatttt     3660

gtggtgggtt tggggcttag ttttcctttt tttcattttg atttttgaaa gtgaagatga     3720

tgccctaatt cctggtaagg atttggggca tagttttttg tttttttgag acggagtttc     3780

gctcttgttg cccaagctgg agtgcagtgg cgcgatctcg gctcactgca acctccgcct     3840

cctgggttca agcagttctc ttgcctcagc ctcccaagta gctgggatga caggcgcaca     3900

ccaccacgcc cagcaaattt tttgtatttt tagtagaaac gggatttcac cttgttaggc     3960

tggtctcgaa ctcctgacct caggtgatcc acccaccttg gcctcccaaa gtgctgggat     4020

tacaggtgtg agccaccacg cccggccgat ttggggcatt tttatttaac agaacttctc     4080

taaccttcca actgcttccc acaaacacat tggcctcaag gctccttaga atcccagttc     4140

cagcttccta aaatagacag tgggtatcgg gcagcagtca ctggggctca agggcagtga     4200

gcaagagaaa tgtctaaagc tgcttctccc aacaccgtcc aaagtctcca ctgcctgagt     4260

tttgtttcgg ctggtttgaa ctcatttcgg gtgtgtgcat ttttcttttg gtacccatgt     4320

gagacatgaa caacaggagg gagggaaaga gcccaggtgg gacgtgggac aggcttaggg     4380

gaaagagctt gtcctatctc aggaacaaaa ttataggctg tgggcagagg gtctgaaagg     4440

tgggctttgg ggtagtgccc aagcctggtc gtgttgccag gagtggtgac aagaaatgca     4500

gcttacatca aacgaacatg tagtgcatgc ccactgcctg atggccagat ggcctgtagg     4560

aagagctacc agggcttcca gacctgtgga acgaagagga tggggaaaag gcagagggca     4620

ctgagtgtcc ctttaaaaac taacccactg aatattccgt gtgatctaga acagtgtggc     4680

agctttcaca gcacaggacc gttcatcggg ggcctaaacg tttccctcag ctctgtcacc     4740

aactcacttc tctcggcttc gttgtctgta aattggatga aaagagctct aatgcctttc     4800

aggctcttag aagccataga tttggacaag cccagcaaga tgggtgtcct tccaggcctc     4860

ttcccctttc ctccatctct ggcaacagtt cttggggttt ggcaattgtt tggatttttt     4920

ttctttctgc agttgtgtgt atgtgtgttt gtgtgaagaa aaacagactc tgtccaggta     4980

gaaatggtga ggagggggaa gagaattaca tttccagggt cagaaacttg gcaacagttt     5040

tcctagagtg actcagacac accacagtaa caactctcgc tgcaatttta ttttaatttg     5100

agaaataaag atttcctcca agccacatga ggactctggc acccacccac aaagcaagac     5160

ctgtatttat aagccgaggg ctcagggagc ctaactgcgg gacccgtcag ggccccgtga     5220

cccatccccg tccccacccc cccctccacc gctgggccca tcagtgtgtg ttggggggat     5280

gcttggcagc tgggggtgag gagacaacaa acctcgggaa ctggagccag agctgcggcc     5340

tgactgacgc cttttgatgc tcacgggaaa tttctgccca ggatctcagc cccaggctgg     5400

ttgtttctac aaatctctct caaatgtatt attttggtga caaaaatgaa ggagctttgt     5460

aaattttttt taaaattatg aatcatatca agtagttgtt tacatttctt gaaaaaatag     5520

gaactcgggc agcagaatca gattggcaga atctttagac tacacaggca ataatcaagt     5580

ctgctgtttt ggcctttcgt agtagaagtg gttgtagtgt ttagatatct gtttggtctt     5640

gcttcttgta ttgcattttt ttcaataaac aacaacaaaa agaactctca aaaa           5694


<210>  566
<211>  2211
<212>  DNA
<213>  homo sapiens

<400>  566
tgttcctccc ggcgtgctcc gcggctcttg gctcacagcc gtcccttcgc tggtgggaag       60

aagccgagat ggcggcagcc agcgctgggg caacccggct gctcctgctc ttgctgatgg      120

cggtagcagc gcccagtcga gcccggggca gcggctgccg ggccgggact ggtgcgcgag      180

gggctggggc ggaaggtcga gagggcgagg cctgtggcac ggtggggctg ctgctggagc      240

actcatttga gatcgatgac agtgccaact tccggaagcg gggctcactg ctctggaacc      300

agcaggatgg taccttgtcc ctgtcacagc ggcagctcag cgaggaggag cggggccgac      360

tccgggatgt ggcagccctg aatggcctgt accgggtccg gatcccaagg cgacccgggg      420

ccctggatgg cctggaagct ggtggctatg tctcctcctt tgtccctgcg tgctccctgg      480

tggagtcgca cctgtcggac cagctgaccc tgcacgtgga tgtggccggc aacgtggtgg      540

gcgtgtcggt ggtgacgcac cccgggggct gccggggcca tgaggtggag gacgtggacc      600

tggagctgtt caacacctcg gtgcagctgc agccgcccac cacagcccca ggccctgaga      660

cggcggcctt cattgagcgc ctggagatgg aacaggccca gaaggccaag aacccccagg      720

agcagaagtc cttcttcgcc aaatactggc acatcatcct ggggggggcc gtgttgctca      780

cagccctgcg tcctgctgcg ccagggcccg cgccaccgcc acaggaggcc tgatggatgt      840

acatcattcc cgtcgtcctg ttcctcatga tgtcaggagc gccagacacc gggggccagg      900

gtgggggtgg gggtgggggt ggtggtgggg gtagtggccg gtgagggccc aggctggtca      960

gcgtcccgtc ttgcacaccc aggggcctcc ctttctgctg gagtcccctg tgtcctcagc     1020

catcccaaga agggtttgct ggtccctcct ttccccccgt cccacgaggc cacctgggcc     1080

agccccttgt cctctgcctt ctgctggcag aggagcagct ggactggggc ctttggcaca     1140

gcagccggtg tctcctgcgc ccgcctcccc catggcccca tgcagcccca ggggcttccc     1200

ccctgcccat ggagtagagc ccgagatcct ggccactatg ccagttctga cctcgcatcc     1260

ccctaccccg agcccatgca gtctgggaac atgccgcctt ctctccagcc tctgtgcctt     1320

tgttccaggt ggtctcaccc tcctgtccct ggctgggcta ggtggtcctg tccaggctcc     1380

tgcagcgccc ccctcacttt gacactggac taggatgcag cctcccttct gtgtcccctt     1440

gagggtaccc tgggtcccct catcaggggc agaggcatga aagagtcggg gctggatggc     1500

cgggggcttc tgggcccgac gcctagtgca gcccctgggg tcgtggtttg acatttgtct     1560

gcctggtgca aacaaggaat ccttgccttt aaggtgacag gccctccaca ggcttccaga     1620

cttgaaggaa aaggtttaag aaagaaaaca aaaccaacag ttagtggagt caaagcccag     1680

acactgtaaa tagaaccccc tccaccaccc cccgccgccc agcatcctac ctggactgcg     1740

gtgctacgag ggcctgcggg cctttgctgt gtgccaccct ccctgtaagt ctatttaaaa     1800

acatcgacga tacattgaaa tgtgtgaacg ttttgaaaag ctacagcttc cagcagccaa     1860

aagcaactgt tgttttggca agacggtcct gatgtacaag cttgattgaa attcactgct     1920

cacttgatac gttattcaga aacccaagga atggctgtcc ccatcctcat gtggctgtgt     1980

ggagctcagc tgtgttgtgt ggcagtttat taaactgtcc cccagatcga cacgcagcta     2040

gcctcctgca ttgtatggtt ataaatagca ccctagtgag tgctgtcgtc cagtctctct     2100

tgggtgtggt ttgaatgatc tcgggatgca tgactaaaat ggaattacga tggcagatcg     2160

gaaacgcgtt tataaacaag tgatggtttg tgagtcgact gtcaagacca g              2211


<210>  567
<211>  2124
<212>  DNA
<213>  homo sapiens

<400>  567
tgttcctccc ggcgtgctcc gcggctcttg gctcacagcc gtcccttcgc tggtgggaag       60

aagccgagat ggcggcagcc agcgctgggg caacccggct gctcctgctc ttgctgatgg      120

cggtagcagc gcccagtcga gcccggggca gcggctgccg ggccgggact ggtgcgcgag      180

gggctggggc ggaaggtcga gagggcgagg cctgtggcac ggtggggctg ctgctggagc      240

actcatttga gatcgatgac agtgccaact tccggaagcg gggctcactg ctctggaacc      300

agcaggatgg taccttgtcc ctgtcacagc ggcagctcag cgaggaggag cggggccgac      360

tccgggatgt ggcagccctg aatggcctgt accgggtccg gatcccaagg cgacccgggg      420

ccctggatgg cctggaagct ggtggctatg tctcctcctt tgtccctgcg tgctccctgg      480

tggagtcgca cctgtcggac cagctgaccc tgcacgtgga tgtggccggc aacgtggtgg      540

gcgtgtcggt ggtgacgcac cccgggggct gccggggcca tgaggtggag gacgtggacc      600

tggagctgtt caacacctcg gtgcagctgc agccgcccac cacagcccca ggccctgaga      660

cggcggcctt cattgagcgc ctggagatgg aacaggccca gaaggccaag aacccccagg      720

agcagaagtc cttcttcgcc aaatactgga tgtacatcat tcccgtcgtc ctgttcctca      780

tgatgtcagg agcgccagac accgggggcc agggtggggg tgggggtggg ggtggtggtg      840

ggggtagtgg ccggtgaggg cccaggctgg tcagcgtccc gtcttgcaca cccaggggcc      900

tccctttctg ctggagtccc ctgtgtcctc agccatccca agaagggttt gctggtccct      960

cctttccccc cgtcccacga ggccacctgg gccagcccct tgtcctctgc cttctgctgg     1020

cagaggagca gctggactgg ggcctttggc acagcagccg gtgtctcctg cgcccgcctc     1080

ccccatggcc ccatgcagcc ccaggggctt cccccctgcc catggagtag agcccgagat     1140

cctggccact atgccagttc tgacctcgca tccccctacc ccgagcccat gcagtctggg     1200

aacatgccgc cttctctcca gcctctgtgc ctttgttcca ggtggtctca ccctcctgtc     1260

cctggctggg ctaggtggtc ctgtccaggc tcctgcagcg cccccctcac tttgacactg     1320

gactaggatg cagcctccct tctgtgtccc cttgagggta ccctgggtcc cctcatcagg     1380

ggcagaggca tgaaagagtc ggggctggat ggccgggggc ttctgggccc gacgcctagt     1440

gcagcccctg gggtcgtggt ttgacatttg tctgcctggt gcaaacaagg aatccttgcc     1500

tttaaggtga caggccctcc acaggcttcc agacttgaag gaaaaggttt aagaaagaaa     1560

acaaaaccaa cagttagtgg agtcaaagcc cagacactgt aaatagaacc ccctccacca     1620

ccccccgccg cccagcatcc tacctggact gcggtgctac gagggcctgc gggcctttgc     1680

tgtgtgccac cctccctgta agtctattta aaaacatcga cgatacattg aaatgtgtga     1740

acgttttgaa aagctacagc ttccagcagc caaaagcaac tgttgttttg gcaagacggt     1800

cctgatgtac aagcttgatt gaaattcact gctcacttga tacgttattc agaaacccaa     1860

ggaatggctg tccccatcct catgtggctg tgtggagctc agctgtgttg tgtggcagtt     1920

tattaaactg tcccccagat cgacacgcag ctagcctcct gcattgtatg gttataaata     1980

gcaccctagt gagtgctgtc gtccagtctc tcttgggtgt ggtttgaatg atctcgggat     2040

gcatgactaa aatggaatta cgatggcaga tcggaaacgc gtttataaac aagtgatggt     2100

ttgtgagtcg actgtcaaga ccag                                            2124


<210>  568
<211>  1017
<212>  DNA
<213>  homo sapiens

<400>  568
gagtatttga ggctcggagc caccgccccg ccggcgcccg cagcacctcc tcgccagcag       60

ccgtccggag ccagccaacg agcggaaaat ggcagacaat ttttcgctcc atgatgcgtt      120

atctgggtct ggaaacccaa accctcaagg atggcctggc gcatggggga accagcctgc      180

tggggcaggg ggctacccag gggcttccta tcctggggcc taccccgggc aggcaccccc      240

aggggcttat cctggacagg cacctccagg cgcctaccct ggagcacctg gagcttatcc      300

cggagcacct gcacctggag tctacccagg gccacccagc ggccctgggg cctacccatc      360

ttctggacag ccaagtgcca ccggagccta ccctgccact ggcccctatg gcgcccctgc      420

tgggccactg attgtgcctt ataacctgcc tttgcctggg ggagtggtgc ctcgcatgct      480

gataacaatt ctgggcacgg tgaagcccaa tgcaaacaga attgctttag atttccaaag      540

agggaatgat gttgccttcc actttaaccc acgcttcaat gagaacaaca ggagagtcat      600

tgtttgcaat acaaagctgg ataataactg gggaagggaa gaaagacagt cggttttccc      660

atttgaaagt gggaaaccat tcaaaataca agtactggtt gaacctgacc acttcaaggt      720

tgcagtgaat gatgctcact tgttgcagta caatcatcgg gttaaaaaac tcaatgaaat      780

cagcaaactg ggaatttctg gtgacataga cctcaccagt gcttcatata ccatgatata      840

atctgaaagg ggcagattaa aaaaaaaaaa agaatctaaa ccttacatgt gtaaaggttt      900

catgttcact gtgagtgaaa atttttacat tcatcaatat ccctcttgta agtcatctac      960

ttaataaata ttacagtgaa ttacctgtct caatatgtca aaaaaaaaaa aaaaaaa        1017


<210>  569
<211>  1973
<212>  DNA
<213>  homo sapiens

<400>  569
gtgtgcaaat agaggaataa atagcagggc agcaactatg tctggaggtc attgtctttc       60

ctgtctcagt agtaatcaat cactgcttat cttcaaaaac ccagagtagg ggatggggca      120

gttagtgggg acagagggca gatgggtaag attcagagca caggctagtg tgacggaagt      180

ttaaacttgt gagttaaata gggtttggca atctagctgg atagcatccc tgccccttga      240

agagatgttt ttgtggcgcc acactactga cttaggcata atgcctagag atggattaga      300

actgcacaat gaactagtgg tgaggttcag tttaatggaa attggtgaaa gcttttagga      360

taaaatgata atctttgttt ctttcaggaa aatggcagac aatttttcgg taagtgtttt      420

atgcctgttt cttccccttg atcagctcca catggttgag ggttgggggt tttgttttta      480

ccatgacttt cccttttcac tctcccactg cgtggcttcc cctggactca tttgtccaat      540

gagggcttgc aagctggagc cttgtttttc cagcagcaga tttgggaaga aagccaggca      600

gagcgaggcc tgggactcac tcacagtaac cctttcacca aaaggcccag ggcggaaggg      660

agtggactct gccggcagga gctgagaaat cctctgagta gcgggaagtg cggtacagtc      720

tgggcattct gatgtttgtg attgtttttc tcacggtgat gaaaaagtat gtgctataag      780

tagaggagcg ctaactcctg acttgagcta attatgaaaa tgcagccctc cctgatctga      840

gacgttggga ggcaagaata aagtgaaaaa gtatatgtaa tcccaacatc taattttagt      900

cttagaaact caaactatta ataagtggaa aaagtttaat gatatgcatg taatgccttt      960

gccatattcc tctccttctt agatcacata ttcctatttt cctgaaaatt ctgcttttga     1020

gaatgctttc tgtcccgtaa ttgtgtatgt ctttctttcc agctccatga tgcgttatct     1080

gggtctggaa acccaaaccc tcaaggatgg cctggcgcat gggggaacca gcctgctggg     1140

gcagggggct acccaggggc ttcctatcct ggggcctacc ccgggcaggc acccccaggg     1200

gcttatcctg gacaggcacc tccaggcgcc taccctggag cacctggagc ttatcccgga     1260

gcacctgcac ctggagtcta cccagggcca cccagcggcc ctggggccta cccatcttct     1320

ggacagccaa gtgccaccgg agcctaccct gccactggcc cctatggcgc ccctgctggg     1380

ccactgattg tgccttataa cctgcctttg cctgggggag tggtgcctcg catgctgata     1440

acaattctgg gcacggtgaa gcccaatgca aacagaattg ctttagattt ccaaagaggg     1500

aatgatgttg ccttccactt taacccacgc ttcaatgaga acaacaggag agtcattgtt     1560

tgcaatacaa agctggataa taactgggga agggaagaaa gacagtcggt tttcccattt     1620

gaaagtggga aaccattcaa aatacaagta ctggttgaac ctgaccactt caaggttgca     1680

gtgaatgatg ctcacttgtt gcagtacaat catcgggtta aaaaactcaa tgaaatcagc     1740

aaactgggaa tttctggtga catagacctc accagtgctt catataccat gatataatct     1800

gaaaggggca gattaaaaaa aaaaaaagaa tctaaacctt acatgtgtaa aggtttcatg     1860

ttcactgtga gtgaaaattt ttacattcat caatatccct cttgtaagtc atctacttaa     1920

taaatattac agtgaattac ctgtctcaat atgtcaaaaa aaaaaaaaaa aaa            1973


<210>  570
<211>  2277
<212>  DNA
<213>  homo sapiens

<400>  570
aatcgaaagt agactctttt ctgaagcatt tcctgggatc agcctgacca cgctccatac       60

tgggagaggc ttctgggtca aaggaccagt ctgcagaggg atcctgtggc tggaagcgag      120

gaggctccac acggccgttg cagctaccgc agccaggatc tgggcatcca ggcacggcca      180

tgacccctcc gaggctcttc tgggtgtggc tgctggttgc aggaacccaa ggcgtgaacg      240

atggtgacat gcggctggcc gatgggggcg ccaccaacca gggccgcgtg gagatcttct      300

acagaggcca gtggggcact gtgtgtgaca acctgtggga cctgactgat gccagcgtcg      360

tctgccgggc cctgggcttc gagaacgcca cccaggctct gggcagagct gccttcgggc      420

aaggatcagg ccccatcatg ctggatgagg tccagtgcac gggaaccgag gcctcactgg      480

ccgactgcaa gtccctgggc tggctgaaga gcaactgcag gcacgagaga gacgctggtg      540

tggtctgcac caatgaaacc aggagcaccc acaccctgga cctctccagg gagctctcgg      600

aggcccttgg ccagatcttt gacagccagc ggggctgcga cctgtccatc agcgtgaatg      660

tgcagggcga ggacgccctg ggcttctgtg gccacacggt catcctgact gccaacctgg      720

aggcccaggc cctgtggaag gagccgggca gcaatgtcac catgagtgtg gatgctgagt      780

gtgtgcccat ggtcagggac cttctcaggt acttctactc ccgaaggatt gacatcaccc      840

tgtcgtcagt caagtgcttc cacaagctgg cctctgccta tggggccagg cagctgcagg      900

gctactgcgc aagcctcttt gccatcctcc tcccccagga cccctcgttc cagatgcccc      960

tggacctgta tgcctatgca gtggccacag gggacgccct gctggagaag ctctgcctac     1020

agttcctggc ctggaacttc gaggccttga cgcaggccga ggcctggccc agtgtcccca     1080

cagacctgct ccaactgctg ctgcccagga gcgacctggc ggtgcccagc gagctggccc     1140

tactgaaggc cgtggacacc tggagctggg gggagcgtgc ctcccatgag gaggtggagg     1200

gcttggtgga gaagatccgc ttccccatga tgctccctga ggagctcttt gagctgcagt     1260

tcaacctgtc cctgtactgg agccacgagg ccctgttcca gaagaagact ctgcaggccc     1320

tggaattcca cactgtgccc ttccagttgc tggcccggta caaaggcctg aacctcaccg     1380

aggataccta caagccccgg atttacacct cgcccacctg gagtgccttt gtgacagaca     1440

gttcctggag tgcacggaag tcacaactgg tctatcagtc cagacggggg cctttggtca     1500

aatattcttc tgattacttc caagccccct ctgactacag atactacccc taccagtcct     1560

tccagactcc acaacacccc agcttcctct tccaggacaa gagggtgtcc tggtccctgg     1620

tctacctccc caccatccag agctgctgga actacggctt ctcctgctcc tcggacgagc     1680

tccctgtcct gggcctcacc aagtctggcg gctcagatcg caccattgcc tacgaaaaca     1740

aagccctgat gctctgcgaa gggctcttcg tggcagacgt caccgatttc gagggctgga     1800

aggctgcgat tcccagtgcc ctggacacca acagctcgaa gagcacctcc tccttcccct     1860

gcccggcagg gcacttcaac ggcttccgca cggtcatccg ccccttctac ctgaccaact     1920

cctcaggtgt ggactagacg gcgtggccca agggtggtga gaaccggaga accccaggac     1980

gccctcactg caggctcccc tcctcggctt ccttcctctc tgcaatgacc ttcaacaacc     2040

ggccaccaga tgtcgcccta ctcacctgag cgctcagctt caagaaatta ctggaaggct     2100

tccactaggg tccaccagga gttctcccac cacctcacca gtttccaggt ggtaagcacc     2160

aggacgccct cgaggttgct ctgggatccc cccacagccc ctggtcagtc tgcccttgtc     2220

actggtctga ggtcattaaa attacattga ggttcctaca aaaaaaaaaa aaaaaaa        2277


<210>  571
<211>  2277
<212>  DNA
<213>  homo sapiens

<400>  571
aatcgaaagt agactctttt ctgaagcatt tcctgggatc agcctgacca cgctccatac       60

tgggagaggc ttctgggtca aaggaccagt ctgcagaggg atcctgtggc tggaagcgag      120

gaggctccac acggccgttg cagctaccgc agccaggatc tgggcatcca ggcacggcca      180

tgacccctcc gaggctcttc tgggtgtggc tgctggttgc aggaacccaa ggcgtgaacg      240

atggtgacat gcggctggcc gatgggggcg ccaccaacca gggccgcgtg gagatcttct      300

acagaggcca gtggggcact gtgtgtgaca acctgtggga cctgactgat gccagcgtcg      360

tctgccgggc cctgggcttc gagaacgcca cccaggctct gggcagagct gccttcgggc      420

aaggatcagg ccccatcatg ctggatgagg tccagtgcac gggaaccgag gcctcactgg      480

ccgactgcaa gtccctgggc tggctgaaga gcaactgcag gcacgagaga gacgctggtg      540

tggtctgcac caatgaaacc aggagcaccc acaccctgga cctctccagg gagctctcgg      600

aggcccttgg ccagatcttt gacagccagc ggggctgcga cctgtccatc agcgtgaatg      660

tgcagggcga ggacgccctg ggcttctgtg gccacacggt catcctgact gccaacctgg      720

aggcccaggc cctgtggaag gagccgggca gcaatgtcac catgagtgtg gatgctgagt      780

gtgtgcccat ggtcagggac cttctcaggt acttctactc ccgaaggatt gacatcaccc      840

tgtcgtcagt caagtgcttc cacaagctgg cctctgccta tggggccagg cagctgcagg      900

gctactgcgc aagcctcttt gccatcctcc tcccccagga cccctcgttc cagatgcccc      960

tggacctgta tgcctatgca gtggccacag gggacgccct gctggagaag ctctgcctac     1020

agttcctggc ctggaacttc gaggccttga cgcaggccga ggcctggccc agtgtcccca     1080

cagacctgct ccaactgctg ctgcccagga gcgacctggc ggtgcccagc gagctggccc     1140

tactgaaggc cgtggacacc tggagctggg gggagcgtgc ctcccatgag gaggtggagg     1200

gcttggtgga gaagatccgc ttccccatga tgctccctga ggagctcttt gagctgcagt     1260

tcaacctgtc cctgtactgg agccacgagg ccctgttcca gaagaagact ctgcaggccc     1320

tggaattcca cactgtgccc ttccagttgc tggcccggta caaaggcctg aacctcaccg     1380

aggataccta caagccccgg atttacacct cgcccacctg gagtgccttt gtgacagaca     1440

gttcctggag tgcacggaag tcacaactgg tctatcagtc cagacggggg cctttggtca     1500

aatattcttc tgattacttc caagccccct ctgactacag atactacccc taccagtcct     1560

tccagactcc acaacacccc agcttcctct tccaggacaa gagggtgtcc tggtccctgg     1620

tctacctccc caccatccag agctgctgga actacggctt ctcctgctcc tcggacgagc     1680

tccctgtcct gggcctcacc aagtctggcg gctcagatcg caccattgcc tacgaaaaca     1740

aagccctgat gctctgcgaa gggctcttcg tggcagacgt caccgatttc gagggctgga     1800

aggctgcgat tcccagtgcc ctggacacca acagctcgaa gagcacctcc tccttcccct     1860

gcccggcagg gcacttcaac ggcttccgca cggtcatccg ccccttctac ctgaccaact     1920

cctcaggtgt ggactagacg gcgtggccca agggtggtga gaaccggaga accccaggac     1980

gccctcactg caggctcccc tcctcggctt ccttcctctc tgcaatgacc ttcaacaacc     2040

ggccaccaga tgtcgcccta ctcacctgag cgctcagctt caagaaatta ctggaaggct     2100

tccactaggg tccaccagga gttctcccac cacctcacca gtttccaggt ggtaagcacc     2160

aggacgccct cgaggttgct ctgggatccc cccacagccc ctggtcagtc tgcccttgtc     2220

actggtctga ggtcattaaa attacattga ggttcctaca aaaaaaaaaa aaaaaaa        2277


<210>  572
<211>  2220
<212>  DNA
<213>  homo sapiens

<400>  572
cccacttttc ccaaacaaag ctcccggcaa ctttctccct cgcagcgccc cgcccgcccg       60

cggctcccca gccccaggcc gggaggccca gatgggggaa ccccgggctg gggccgccct      120

ggacgatggc agcggctgga cgggcagtga ggaaggcagt gaggagggta ccggcggcag      180

tgagggggct gggggtgacg ggggcccgga tgcagagggg gtgtggagcc cagacattga      240

gcagagcttc caggaggccc tggccatcta tccaccctgc ggccgccgga aaataatttt      300

gtctgatgaa ggcaagatgt atggtcggaa tgaactgatc gcccgctaca tcaagctgag      360

aacggggaag acccgaactc gaaaacaggt ttctagtcac atccaggttt tggcccgaag      420

gaaatcaagg gaaatccagt ccaagttgaa ggaccaggtt tccaaggaca aggctttcca      480

gacaatggca accatgtcct ctgcccagct catctccgcg ccttctctgc aggccaaact      540

gggtcccact ggtcctcagg cctctgagct tttccagttt tggtctggag gatctgggcc      600

cccctggaat gttccagatg tgaagccatt ctcacagaca ccgttcacct tgtcactgac      660

tcccccatct actgacctcc cagggtacga gcccccccaa gccctctcac ccctgccccc      720

acctacccca tcgcccccag cctggcaggc tcggggcctg ggcaccgccc ggttgcagct      780

ggtagagttc tcagccttcg tggaaccgcc agatgcagtt gattcttacc agaggcacct      840

gttcgtgcac atcagccagc actgccccag ccccggagcg ccgccgctcg agagtgtgga      900

cgtccggcag atctacgaca aattccctga gaaaaagggt ggcctccgag agctatatga      960

tcgtggcccc ccccatgcct tcttcctggt caagttctgg gcggacctga actggggccc     1020

aagtggtgag gaggcagggg ccggtggcag catcagcagt ggtggcttct acggagtgag     1080

cagccagtat gagagcctgg aacacatgac cctcacctgt tcctccaagg tctgctcttt     1140

tggcaagcag gtggtggaga aggtggagac ggaacgggcc cagctggagg acggcagatt     1200

tgtgtaccgc ctgctgcgct cgcccatgtg cgagtacctg gtgaatttct tgcacaagtt     1260

gcggcagctg cctgagcgat acatgatgaa cagcgtcctg gaaaacttca ccatcctcca     1320

ggtggtgaca aacagagaca cccaggaact gctgctctgc accgcctatg tcttcgaggt     1380

ctccaccagc gagcgtgggg cccagcatca catttaccgc ctggtcaggg actgaagggg     1440

gaccccaaaa ctggctcacc ccccagaaca ccctcctccc agggagggtc ctccagctca     1500

cctcatgctt cttatttggg gagagggctg tgatgtaaag gggttgacct cagaggccta     1560

agcaactggg gccatccccc ccattagagg ggcccccaaa acttggttgg agagctgaac     1620

aggctgggac tgaggaaagg ataaaccccg atattgggac ctcacagtgg gtgtctgaaa     1680

ggacagatca ctccggagta tcagggattg tggggacagg agtgagacaa ccccccaggt     1740

acagcactgg cttttctttt cagcccctga caggccaccc ccactcctct gcatgtcttg     1800

gagagcgcta gttacacatt ggcttgtccc ctttactttt tcccagccac ccctccccct     1860

gaaatttctg cccctctcta ccaccctcac tccatgacct gtgagatcac aaagtgaaga     1920

tgaacccttt ctgtgcagga gcagagccag gtgggccctg gacatttttt ttttttttaa     1980

tataacgaga tatttataag tgggtgctag ggtcttgact ttatctccgc tgcacaagca     2040

gtgtgttgaa ctttctaatc tcatccctct cctaagtgag ccctgagcta gacggtttcc     2100

ttcctcccct ctcaaagttt gtttgtttgt gttctgacag aggataaagc tattttacca     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220


<210>  573
<211>  4398
<212>  DNA
<213>  homo sapiens

<400>  573
agctggcagg tggccgagcc gggggtggac gggcgggctg ggactggtgc tggccattgg       60

ctgcctcaag gctcccaccc cgcctgcctc cctagcctgc ggctggcggc ccctgcctct      120

ccagctgcct ctgaactccc tggagcaagc acctcctgct gggctgtgtg agctgcgact      180

ggttctcagt ggcccctgcc atggacatgc ctgaggtcct caagtccctg ctggagcact      240

ctctgccttg gccagagaag agaacagata aggaaaaggg gaaggaaaag ctggaggagg      300

acgaggccgc agccgccagc accatggctg tctcagcctc cctcatgcca cccatctggg      360

acaagaccat cccatatgat ggcgaatctt tccacctgga gtacatggac ctggatgagt      420

tcctgctgga gaatggcatc cccgccagcc ccacccacct ggcccacaac ctgctgctgc      480

ctgtagcaga gctagaaggg aaggagtctg ccagctcttc cacagcatcc ccaccatcct      540

cctccactgc catctttcag ccctctgaaa ccgtgtccag cacagaatct tccctggaga      600

aggagaggga gactcccagt cccatcgacc ccaattgtgt ggaagtggat gtgaacttca      660

atccggaccc cgccgacctg gtgctctcca gtgtgccagg cggggagctc ttcaaccctc      720

ggaagcacaa gtttgctgag gaggacctga agccccagcc tatgatcaaa aaggccaaga      780

aggtctttgt ccccgacgag cagaaggatg aaaagtactg gacaagacgc aagaagaaca      840

acgtggcagc taaacggtca cgggatgccc ggcgcctgaa agagaatcag atcaccatcc      900

gggcagcctt cctggagaag gagaacacag ccctgcggac ggaggtggcc gagctacgca      960

aggaggtggg caagtgcaag accatcgtgt ccaagtatga gaccaaatac gggcccttgt     1020

aacccgtgcc ccccgcccgg gcggggtact gcctgcacct cagacctctg cctgggggct     1080

ccctgtaacc cctcacacgc gtggagactt atgactcgtc gtgggcgcat ggcggcgcac     1140

ctgctgcagg agcggccacg tctcagcttc attataccat ggcctgcgca cgtggcgacg     1200

tccctgaggg gccagtctcc tcactggtgg ggaacgcaag agaatctgcg tagatgggtg     1260

actcagcctt agtttctatt cttggatgtc ccagttgaat cagaagggga cctctggagt     1320

acacacctct ctcctgggcg ctcagggtcc ctggactctc cctcagtctc cagcctgggc     1380

tgccgagggc tatctctgca gaatgagttg tgatcattgt caccctatgt cttctcaggt     1440

agcagggcgc gtttccactt aaggtgtgtc tgtcacgcac ctcattctcc ccagacagtc     1500

tttgagtaac atctgttccc atcttccttg gaagcaggac acaccagctc ctccgtcagt     1560

gtctgcatgg gtagcaggct gcaggagtgg ggtctctgca cagcctggga tggggcttgg     1620

ggctggggcc tgcagcagaa gtgtgcccag cgtttctcgg ctcccgcacc ccttttccct     1680

tatggctctg aggccatcgg ctgtctctgc atttcattgg ctgtggagga gagactccta     1740

ggatggctgc tgtctgagcc atgagtgcca gggctgagag aggcctcttc atttcctctc     1800

caggctactc agaggccatg tgaagctcgt ttgtcccact agaccaggcc tctgggcctg     1860

ctctttcttt ccacccaatg tccagtcttg gatcatagat ttaaaaggaa aacccctctt     1920

atctaggagg ctttaacttc ctggacccca ggattcacct tcctagtggt gtttagaaaa     1980

tgcctccaca gcccccttcc accatgggca tgagagctgg ggtgtgtttc ttgagaagct     2040

cccttttttc ttgctctgct caccggtgtg gcctgggctg gagtgcactc tccctggggg     2100

cagctggggc ctcgcaattc ttgcttcagg atctctccca tgcgagctgc ccggagggtg     2160

tcagcagggc aagacaccta gtctagagtc accaaggtca cagtgccact ttcacgggat     2220

agcaggctct tgggactttt acacaggcct agggtcccct cagtcttggt cccaggagat     2280

gggggccact cgtgaggctg gccatgctgt ggcttctcac agctgtggtc tcccctgcct     2340

cacaacgact cctttctctt gtgtggcggg actcgccctt ttgctgtgct cagaagattc     2400

actgaggaaa ctcatggaag cctctgctca tttgggtcac tgggacaccc ctgagatggg     2460

tgtgtttatt tgctcagggc gggcagccta tggtgaagag gagacagagg cgatgggcgt     2520

gcttcgtcct ccgtaacact ggctttattt accgtggtgg ttcagagtcc caggccctga     2580

cctctaaaga cttttcataa cagacgttaa gaccaagccg tggacctcac cccaggggaa     2640

tgccacggcc ctttggggac ctgcacaccc acctctccgg gggacttgac aaggggccct     2700

gaggccaagg gaggtcactc ctccctccag gcccctgact tttactttgt ggttctctaa     2760

aaaccatgta cacactttca ctctattgta accacacagg gcaggcgcat ccagcatgtc     2820

agtgtcctgc cccgggcagc tctccctccc gggcacgctc cctctggcct ggtggatcac     2880

caagagggcg gttctcattt tgttattagt ggaagagcct tgagcttaaa agctcttcat     2940

tttctttgcc ggaaagtata tggtttgtgt ttttgcagtt ttattttttt aaggatggac     3000

actaaatctc tggtgtccat gttccgagcc cggtggctgg gatggtggct cgatgtgtct     3060

cctctttatc ccgccctctg cctgtttggt gccctccctt ctttccccca ggcagtgggt     3120

atcgggttct ttcccaaagt gcttacttgg aaagagtgtg gctgctggac tcttttcgaa     3180

atgcccctct gagtcaggag cctggtgggg acaagatgga ggatgtccac agaggctgac     3240

ctgtggggga aaagaagtgc tcaggtaagg ttgtctcctc tcctgtccta aaaaaatcca     3300

tgcttgcagg agagggttgg tgcctgctca gtttctgtcg agggaatggg agtctcctcg     3360

gctccctcct gggccctctg cttcttggag gccgaccgct ggagactgcg gctcctgtgc     3420

ttggatcttt gacatctgtc agtcactgga ggctagagaa gttgacttta ccttggcttt     3480

ctgtgggttc ccgatgggct tggaagtgcc gtctacttcc taagcatcct gtctaaagct     3540

ttgtggcacc ctcagtgcaa cctcagaaca gacaaatcat gaatgagctg gaactttgca     3600

agaatattca tattataaat gtctcatctg atggaggaac gtgtgcattt agagagaggg     3660

agagttttca aggtttatgg caactttgtg gaggacctgg gtaactctta cccttggcca     3720

aaggaagagg ttttcctgtc tggcttctga ggttggaggg ggcacttagc agtgaacctt     3780

aagtctgggt acatgtaacc ctgctgaggg gctgtgcagg ccgctcctac ggtcctttgg     3840

cctgaggcag ggcgggaggc atgcaagcca gtgggggaaa acccctctga agctgggcag     3900

ccctctacct gggccccggg agccgtgctc cttggaacgc aaagggccga ggagcatctg     3960

gttttcatgg caaagctcta ctccagagct cctttaacat ctgctaatta agtgcaataa     4020

atttttctag aaaatggcaa agatgacttc caggtggata ttgctctctt acggtgttgg     4080

ggatgccaga acaccacttg gttttatttt tctaagtgca tgtgatgtga tagagtgtgt     4140

ggggctctgt gtccttccct gggagctggc attccagcgg gcccctctct ttacctttgt     4200

tgggggaagg aggcaagaga gaaattcctt cttcccagcc agagagggca gaagcagacc     4260

gtagcccatt ggccttatgt gcgtgtgtgc gtgcgagtgt gtcactgctg gtgggccgga     4320

gtgatgtggt gggagggaag ccgggaatgt atccttttca gacaaaatta aatattttga     4380

aatgagaatg aaaaaaaa                                                   4398


<210>  574
<211>  4404
<212>  DNA
<213>  homo sapiens

<400>  574
attgggcgcc tgcgcagtag ctgcccgtgt cggcagctgc agcgggtcgc acggctccgg       60

cccatctcgg ggggcgggcg ggggaggcga ggtgcgcgag ccgagtccgg ggcacgatgt      120

ccgacgcggg cggcggaaag aagccgcctg tggacccgca ggcaggaccc ggtccggggc      180

cggggcgcgc agctggggaa aggggcctgt cggggtcctt ccccctggtc ctgaagaagc      240

tgatggagaa ccccccgcgc gaggcgcgcc tcgataagga aaaggggaag gaaaagctgg      300

aggaggacga ggccgcagcc gccagcacca tggctgtctc agcctccctc atgccaccca      360

tctgggacaa gaccatccca tatgatggcg aatctttcca cctggagtac atggacctgg      420

atgagttcct gctggagaat ggcatccccg ccagccccac ccacctggcc cacaacctgc      480

tgctgcctgt agcagagcta gaagggaagg agtctgccag ctcttccaca gcatccccac      540

catcctcctc cactgccatc tttcagccct ctgaaaccgt gtccagcaca gaatcttccc      600

tggagaagga gagggagact cccagtccca tcgaccccaa ttgtgtggaa gtggatgtga      660

acttcaatcc ggaccccgcc gacctggtgc tctccagtgt gccaggcggg gagctcttca      720

accctcggaa gcacaagttt gctgaggagg acctgaagcc ccagcctatg atcaaaaagg      780

ccaagaaggt ctttgtcccc gacgagcaga aggatgaaaa gtactggaca agacgcaaga      840

agaacaacgt ggcagctaaa cggtcacggg atgcccggcg cctgaaagag aatcagatca      900

ccatccgggc agccttcctg gagaaggaga acacagccct gcggacggag gtggccgagc      960

tacgcaagga ggtgggcaag tgcaagacca tcgtgtccaa gtatgagacc aaatacgggc     1020

ccttgtaacc cgtgcccccc gcccgggcgg ggtactgcct gcacctcaga cctctgcctg     1080

ggggctccct gtaacccctc acacgcgtgg agacttatga ctcgtcgtgg gcgcatggcg     1140

gcgcacctgc tgcaggagcg gccacgtctc agcttcatta taccatggcc tgcgcacgtg     1200

gcgacgtccc tgaggggcca gtctcctcac tggtggggaa cgcaagagaa tctgcgtaga     1260

tgggtgactc agccttagtt tctattcttg gatgtcccag ttgaatcaga aggggacctc     1320

tggagtacac acctctctcc tgggcgctca gggtccctgg actctccctc agtctccagc     1380

ctgggctgcc gagggctatc tctgcagaat gagttgtgat cattgtcacc ctatgtcttc     1440

tcaggtagca gggcgcgttt ccacttaagg tgtgtctgtc acgcacctca ttctccccag     1500

acagtctttg agtaacatct gttcccatct tccttggaag caggacacac cagctcctcc     1560

gtcagtgtct gcatgggtag caggctgcag gagtggggtc tctgcacagc ctgggatggg     1620

gcttggggct ggggcctgca gcagaagtgt gcccagcgtt tctcggctcc cgcacccctt     1680

ttcccttatg gctctgaggc catcggctgt ctctgcattt cattggctgt ggaggagaga     1740

ctcctaggat ggctgctgtc tgagccatga gtgccagggc tgagagaggc ctcttcattt     1800

cctctccagg ctactcagag gccatgtgaa gctcgtttgt cccactagac caggcctctg     1860

ggcctgctct ttctttccac ccaatgtcca gtcttggatc atagatttaa aaggaaaacc     1920

cctcttatct aggaggcttt aacttcctgg accccaggat tcaccttcct agtggtgttt     1980

agaaaatgcc tccacagccc ccttccacca tgggcatgag agctggggtg tgtttcttga     2040

gaagctccct tttttcttgc tctgctcacc ggtgtggcct gggctggagt gcactctccc     2100

tgggggcagc tggggcctcg caattcttgc ttcaggatct ctcccatgcg agctgcccgg     2160

agggtgtcag cagggcaaga cacctagtct agagtcacca aggtcacagt gccactttca     2220

cgggatagca ggctcttggg acttttacac aggcctaggg tcccctcagt cttggtccca     2280

ggagatgggg gccactcgtg aggctggcca tgctgtggct tctcacagct gtggtctccc     2340

ctgcctcaca acgactcctt tctcttgtgt ggcgggactc gcccttttgc tgtgctcaga     2400

agattcactg aggaaactca tggaagcctc tgctcatttg ggtcactggg acacccctga     2460

gatgggtgtg tttatttgct cagggcgggc agcctatggt gaagaggaga cagaggcgat     2520

gggcgtgctt cgtcctccgt aacactggct ttatttaccg tggtggttca gagtcccagg     2580

ccctgacctc taaagacttt tcataacaga cgttaagacc aagccgtgga cctcacccca     2640

ggggaatgcc acggcccttt ggggacctgc acacccacct ctccggggga cttgacaagg     2700

ggccctgagg ccaagggagg tcactcctcc ctccaggccc ctgactttta ctttgtggtt     2760

ctctaaaaac catgtacaca ctttcactct attgtaacca cacagggcag gcgcatccag     2820

catgtcagtg tcctgccccg ggcagctctc cctcccgggc acgctccctc tggcctggtg     2880

gatcaccaag agggcggttc tcattttgtt attagtggaa gagccttgag cttaaaagct     2940

cttcattttc tttgccggaa agtatatggt ttgtgttttt gcagttttat ttttttaagg     3000

atggacacta aatctctggt gtccatgttc cgagcccggt ggctgggatg gtggctcgat     3060

gtgtctcctc tttatcccgc cctctgcctg tttggtgccc tcccttcttt cccccaggca     3120

gtgggtatcg ggttctttcc caaagtgctt acttggaaag agtgtggctg ctggactctt     3180

ttcgaaatgc ccctctgagt caggagcctg gtggggacaa gatggaggat gtccacagag     3240

gctgacctgt gggggaaaag aagtgctcag gtaaggttgt ctcctctcct gtcctaaaaa     3300

aatccatgct tgcaggagag ggttggtgcc tgctcagttt ctgtcgaggg aatgggagtc     3360

tcctcggctc cctcctgggc cctctgcttc ttggaggccg accgctggag actgcggctc     3420

ctgtgcttgg atctttgaca tctgtcagtc actggaggct agagaagttg actttacctt     3480

ggctttctgt gggttcccga tgggcttgga agtgccgtct acttcctaag catcctgtct     3540

aaagctttgt ggcaccctca gtgcaacctc agaacagaca aatcatgaat gagctggaac     3600

tttgcaagaa tattcatatt ataaatgtct catctgatgg aggaacgtgt gcatttagag     3660

agagggagag ttttcaaggt ttatggcaac tttgtggagg acctgggtaa ctcttaccct     3720

tggccaaagg aagaggtttt cctgtctggc ttctgaggtt ggagggggca cttagcagtg     3780

aaccttaagt ctgggtacat gtaaccctgc tgaggggctg tgcaggccgc tcctacggtc     3840

ctttggcctg aggcagggcg ggaggcatgc aagccagtgg gggaaaaccc ctctgaagct     3900

gggcagccct ctacctgggc cccgggagcc gtgctccttg gaacgcaaag ggccgaggag     3960

catctggttt tcatggcaaa gctctactcc agagctcctt taacatctgc taattaagtg     4020

caataaattt ttctagaaaa tggcaaagat gacttccagg tggatattgc tctcttacgg     4080

tgttggggat gccagaacac cacttggttt tatttttcta agtgcatgtg atgtgataga     4140

gtgtgtgggg ctctgtgtcc ttccctggga gctggcattc cagcgggccc ctctctttac     4200

ctttgttggg ggaaggaggc aagagagaaa ttccttcttc ccagccagag agggcagaag     4260

cagaccgtag cccattggcc ttatgtgcgt gtgtgcgtgc gagtgtgtca ctgctggtgg     4320

gccggagtga tgtggtggga gggaagccgg gaatgtatcc ttttcagaca aaattaaata     4380

ttttgaaatg agaatgaaaa aaaa                                            4404


<210>  575
<211>  5217
<212>  DNA
<213>  homo sapiens

<400>  575
gggggcgttg tctgggggcg gggctccggc cgcctctgac gagtcccgga tttaccaggg       60

ccggtgggat cccctcgggc tcccgcctta gcatgctggc cgggacatct ggtgaacatg      120

gcctctgcta ctgcggcagc agcacgacgg ggcctcggcc gggctctccc tctcctctgg      180

cgtggctacc agaccgagcg gggcgtttac ggctaccggc cgaggaagcc cgagagccgc      240

gagccccagg gcgccctgga gcgcccccca gttgatcatg gccttgccag gttggtgaca      300

gtatattgtg agcatggtca taaagctgcc aaaatcaacc ccctcttcac cggacaagcc      360

ctgctggaga atgtgcctga aatccaagcc ctggtgcaga cactgcaggg acccttccac      420

acggcaggat tattgaacat ggggaaggaa gaggcctcac ttgaggaagt gttagtctat      480

ctcaatcaaa tctactgtgg gcagatttct attgaaacct cccaacttca gagccaggat      540

gagaaagact ggtttgccaa gcggtttgag gaactgcaaa aggagacgtt taccacagaa      600

gagcgaaaac atctgtcgaa actaatgctg gaatctcagg agtttgacca ctttctggcc      660

accaagttct cgacagtgaa gcgatatgga ggcgaagggg ctgaaagcat gatgggcttt      720

ttccacgagc tgctgaaaat gtcggcctac agcgggatca ctgatgtcat tattgggatg      780

ccccatagag ggaggctgaa tttattgaca ggccttctgc agttccctcc agagctgatg      840

ttccgtaaaa tgcgaggctt aagtgaattt ccagagaatt tctcagccac tggagacgtc      900

ctgtctcacc tgacctcctc tgtggacctg tactttgggg cgcaccatcc cctccatgtg      960

acaatgttgc ccaatccctc gcacctggag gccgtcaacc ccgtggccgt gggcaaaact     1020

cgcggcaggc agcagtctcg ccaagacggc gattactctc cagacaactc agcccagccg     1080

ggggacaggg tcatttgctt acaggtccat ggtgatgctt ctttctgtgg tcaagggatt     1140

gttcctgaaa cattcacgct gtccaatctc ccacatttca gaattggtgg gagtgtgcat     1200

ttgattgtta ataaccagct gggttacacc actccagctg aaagaggaag gtcttcttta     1260

tactgcagtg atattgggaa gcttgtgggc tgtgccatca tccatgtcaa tggagacagc     1320

ccagaggaag tggtccgtgc cacacgactg gcttttgaat accaacgcca gttccgcaag     1380

gatgtgatta ttgatctgtt gtgctacagg cagtggggcc acaatgagct ggatgagcca     1440

ttctacacca accccatcat gtacaaaatc atcagagctc gaaagagcat tccagacaca     1500

tatgcagagc acctcattgc tggcggactc atgacgcagg aggaggtgtc tgaaataaaa     1560

tcctcctact atgccaagtt gaatgatcac ttaaataaca tggcccacta caggccccct     1620

gccctgaacc tgcaggccca ctggcagggc ctggctcagc cagaagcgca aatcaccacc     1680

tggagtacag gtgtgcccct cgacctcctg cggtttgttg gcatgaagtc tgtagaggtg     1740

ccaagagagc tgcagatgca cagtcacctg ctgaagacac atgttcagtc cagaatggag     1800

aagatgatgg acggaatcaa gctagactgg gccaccgcgg aagctcttgc cttgggttct     1860

ttacttgctc aaggttttaa tgttcgtcta agtggccaag atgttggtcg tggaactttc     1920

agtcagaggc atgcaatcgt ggtttgccag gagacggatg acacctacat ccccctgaac     1980

catatggacc caaatcagaa ggggtttcta gaggtcagca acagccccct gtcagaagag     2040

gccgtcctgg gattcgaata tgggatgagc attgagagcc caaagttact gcccctgtgg     2100

gaggcacagt ttggcgattt cttcaatggt gcccagatca tctttgacac attcatctct     2160

ggaggagagg ccaagtggct cctacaaagc ggcatcgtca tcctccttcc acatggctac     2220

gatggggctg ggccagacca ctcatcctgt cgaatagagc gtttcctgca gatgtgtgac     2280

agtgcggaag agggggtgga cggagacact gtgaacatgt ttgtggttca cccaacaact     2340

cctgcacagt atttccactt gcttaggaga cagatggtcc ggaacttcag aaaaccactc     2400

attgttgctt cccctaagat gttactcagg ctcccggcag ccgtgtcaac tcttcaagaa     2460

atggcaccag gaacaacatt taacccggtc attggtgatt catctgtgga tccaaaaaag     2520

gttaagaccc tcgtgttctg ctccggcaaa catttctact ccctggtgaa acaaagagaa     2580

tctctggggg ccaagaagca tgactttgcc atcatccgag tagaggaact ctgccccttc     2640

ccgttggatt ctttacagca agagatgagc aaatacaaac atgttaaaga tcatatttgg     2700

agtcaggagg aacctcagaa catgggtccg tggtcgtttg tttctccaag gtttgaaaag     2760

cagctggcct gcaagctccg tctggtgggc cggccccctt tgccagtacc cgctgtagga     2820

attggcacag ttcacttgca ccagcatgaa gatatcctcg ccaagacctt cgcttgatga     2880

tgacttttga agaaacacta tttctcttta agaaaatggc cattaaggcc gggtggggtg     2940

gcacatgcct gtaatcccag cactttggga ggccaaggct ggtggatcac ctgaggtcag     3000

gagttcgaga ccagcctggc caacacggtg aaaccccgcc tctactaaaa atacaaaaaa     3060

tagccgggtg tggtggtggg cacctgtgat cccagcttcc tgggaggctg aggcaagaga     3120

atcgcttgaa tctgggaggc ggaggttgca gtgagccagg atcacaccat tgctgtccag     3180

cctgggtgac agagcaagac tgcgtttcaa aaaaaaaaaa aaaaaaaccc attaaaagag     3240

gcctccttcc tccactctct caacccctct gttgggtaac atgaaaagac tgtattcctc     3300

taagatgttg ggattgatat acgtgattta atctgcaata ggtggaataa ccaggggaac     3360

tggttatgaa tatgtgaatg caaccagcaa atttatcctt gaaggtgtga tggtagaaat     3420

aggaaaacaa caaaagaaaa acaataacaa aaaaagaaag tgtgatggct gggtgcagtg     3480

gctcacgcct gtaatcccag cactttggga ggcttaggcg gctggatcac ctgaggtcag     3540

gagttcaaga ccagcctggt caacgtggtg aaacgccgtt tctactaaaa atatgaaaat     3600

tagttgggtg tggtggcatg cgcttgtagt ctcagctact ccggaggctg aggcaggaga     3660

attgcttgaa cctggaaggc agaggttgca gtgagccgaa atggcgccac tgtactccaa     3720

cctgggcgac agagcaagac tccatctcat aaattaaaag gaaagtatga tagtgttatg     3780

gattttagct ctgagtgagc tggaaaacta ggtcattatc tagatgattt cagacttgac     3840

cctaattgac catatatgac caggaaacac ttctgagttt acagctccgt ggagatgacc     3900

tcaacactgc ctcttgattt gtttgatgca tgtcactttc attaattttc cccctccttt     3960

ttgaaagtcc tgtggcagta ctaatatttt cattttatgt aatctctggt gctgctttcc     4020

agtcactgta tgaagtgtct ccccaacact agcaaatcta ggtcctacta aatacaaatc     4080

tctgggtgga tgatcttcta gtactgtatt tttaaattaa ggagttttag ttataatgaa     4140

attgatttgt agtctgtttt gccgtaaact tgtttttctt taaattgttc ttacagtgat     4200

atcttactat ttttaactgt ctggggtttc tgatatgggg atttcagccc ctggttaatc     4260

agtcttgtcc ctacaagtcc ctgatgcagt atgtttattt gtgatgttta aagaacattt     4320

cttggctggg cgctgcggct tgcgcctgta atctcagcac tttgggaggc tgagatgggt     4380

ggatcacctg aggttgggag ttcgagacca gcctgacaaa acatagtgaa accccgtctc     4440

tactaaaaat acaaaaatta gctgggcgtg gtggtgggtg tctgtaatcc cagctattcg     4500

ggaggctgag gcaggagaat cgcttgaacc caggaggtgg aggttgcagt gagctgagat     4560

cctgccactg cactccagtc tgggtgacag agcaagactc catctcaaaa aataaataaa     4620

tagaaagaga gagagaggaa aaaaaaagaa aagaacactt ctttatttga gggactttcc     4680

caacaccagg tgcttgggga tttcttagag atcaccaacc gactccctca ctgtgaaatt     4740

aaaccaagta ctggaaacgt aactaaacag cgaaccatgt agcttcacct gactcagtgc     4800

tgggggcctc taccatctac tgtgcttgtg tcatgatgct ttttctctga agtggtgtgg     4860

gaagtaccag gggactggca gaagcccagg ccctctctac ttttaccagc aactgatcat     4920

gtctttcaga atccatgtac atataggctg ttctagccac agtggtagat ttatgattca     4980

catccgaaag tgtgccttag ttatcaattt aacatttctc tagtattcat atcccttttc     5040

ttaccatata cctcagtgta tccttcctgt gtcaagcctt ataaatcatg taatttagtg     5100

ccactcatgt aaatcagtaa aatcacaaag gtctatttaa tgaaaacgat ttaccaatgt     5160

tgtttttttt taacaagaaa aaaaataaaa gcacattgtc attttttttc ctcagga        5217


<210>  576
<211>  3958
<212>  DNA
<213>  homo sapiens

<400>  576
tttttttttt ttttttgctt aaaaaaaagc catgacggct ctcccacaat tcatcttccc       60

tgcgccatct ttgtattatt tctaatttat tttggatgtc aaaaggcact gatgaagata      120

ttttctctgg agtctccttc tttctaaccc ggctctcccg atgtgaaccg agccgtcgtc      180

cgcccgccgc cgccgccgcc gccgccgccg cccgccccgc agcccaccat gtctcgccgc      240

aagcaaggca aaccccagca cttaagcaaa cgggaattct cgcccgagcc tcttgaagcc      300

attcttacag atgatgaacc agaccacggc ccgttgggag ctccagaagg ggatcatgac      360

ctcctcacct gtgggcagtg ccagatgaac ttcccattgg gggacattct tatttttatc      420

gagcacaaac ggaaacaatg caatggcagc ctctgcttag aaaaagctgt ggataagcca      480

ccttcccctt caccaatcga gatgaaaaaa gcatccaatc ccgtggaggt tggcatccag      540

gtcacgccag aggatgacga ttgtttatca acgtcatcta gaggaatttg ccccaaacag      600

gaacacatag cagataaact tctgcactgg aggggcctct cctcccctcg ttctgcacat      660

ggagctctaa tccccacgcc tgggatgagt gcagaatatg ccccgcaggg tatttgtaaa      720

gatgagccca gcagctacac atgtacaact tgcaaacagc cattcaccag tgcatggttt      780

ctcttgcaac acgcacagaa cactcatgga ttaagaatct acttagaaag cgaacacgga      840

agtcccctga ccccgcgggt tggtatccct tcaggactag gtgcagaatg tccttcccag      900

ccacctctcc atgggattca tattgcagac aataacccct ttaacctgct aagaatacca      960

ggatcagtat cgagagaggc ttccggcctg gcagaagggc gctttccacc cactcccccc     1020

ctgtttagtc caccaccgag acatcacttg gacccccacc gcatagagcg cctgggggcg     1080

gaagagatgg ccctggccac ccatcacccg agtgcctttg acagggtgct gcggttgaat     1140

ccaatggcta tggagcctcc cgccatggat ttctctagga gacttagaga gctggcaggg     1200

aacacgtcta gcccaccgct gtccccaggc cggcccagcc ctatgcaaag gttactgcaa     1260

ccattccagc caggtagcaa gccgcccttc ctggcgacgc cccccctccc tcctctgcaa     1320

tccgcccctc ctccctccca gcccccggtc aagtccaagt catgcgagtt ctgcggcaag     1380

acgttcaaat ttcagagcaa cctggtggtg caccggcgca gccacacggg cgagaagccc     1440

tacaagtgca acctgtgcga ccacgcgtgc acccaggcca gcaagctgaa gcgccacatg     1500

aagacgcaca tgcacaaatc gtcccccatg acggtcaagt ccgacgacgg tctctccacc     1560

gccagctccc cggaacccgg caccagcgac ttggtgggca gcgccagcag cgcgctcaag     1620

tccgtggtgg ccaagttcaa gagcgagaac gaccccaacc tgatcccgga gaacggggac     1680

gaggaggaag aggaggacga cgaggaagag gaagaagagg aggaagagga ggaggaggag     1740

ctgacggaga gcgagagggt ggactacggc ttcgggctga gcctggaggc ggcgcgccac     1800

cacgagaaca gctcgcgggg cgcggtcgtg ggcgtgggcg acgagagccg cgccctgccc     1860

gacgtcatgc agggcatggt gctcagctcc atgcagcact tcagcgaggc cttccaccag     1920

gtcctgggcg agaagcataa gcgcggccac ctggccgagg ccgagggcca cagggacact     1980

tgcgacgaag actcggtggc cggcgagtcg gaccgcatag acgatggcac tgttaatggc     2040

cgcggctgct ccccgggcga gtcggcctcg gggggcctgt ccaaaaagct gctgctgggc     2100

agccccagct cgctgagccc cttctctaag cgcatcaagc tcgagaagga gttcgacctg     2160

cccccggccg cgatgcccaa cacggagaac gtgtactcgc agtggctcgc cggctacgcg     2220

gcctccaggc agctcaaaga tcccttcctt agcttcggag actccagaca atcgcctttt     2280

gcctcctcgt cggagcactc ctcggagaac gggagtttgc gcttctccac accgcccggg     2340

gagctggacg gagggatctc ggggcgcagc ggcacgggaa gtggagggag cacgccccat     2400

attagtggtc cgggcccggg caggcccagc tcaaaagagg gcagacgcag cgacacttgt     2460

tcttcacaca cccccattcg gcgtagtacc cagagagctc aagatgtgtg gcagttttcg     2520

gatggaagct cgagagccct taagttctga gaaaatttga agcccccagg ggtggggtgg     2580

acgcgtgccg cccagtcgac gtcagcgtgg tctgtcatcc tgctagtttg tgatgttttc     2640

tgacagtagc ctccaagaag ccgttgtgcg aagacagagt cctgcagagt ccttccagcc     2700

taggcctgca gcgccatttt atttatattt tttaataaaa agtaaaaaca aaaaaacaga     2760

cccacattgg aacagtgaat cagtcccata gagagggccc gtggaccatc gctgtcatga     2820

gtgatgccct ggcccttctg aaaccagcca acctaattac ctgtattgtg gaaatgcgca     2880

tgagtcccca accccttgtt tctatacatt ctatgttgtc ttttaaaaag tgtgcttaac     2940

attgacacaa taaatgttgg agctttaggt ggtgtttgct tgttctttaa tttttaatgc     3000

ttataagaca atgaggctgc ttatgatttt gtacttctgt acctgtttcc tacagacacc     3060

catcgggtgg gtaggaggaa cagatttgag aaatgggcag gagatgtagg aggggaacta     3120

ggttaccgct tatcagatgg cataaatttt caaggagaat caaaatgcaa aacttgggaa     3180

taaatcatag caatatcata attaatgtag tagtaatatt gctgtttatt aatgctgaag     3240

tgtggttttc ctaactgtct gacttataat ttgcatacca ttaaataatg cataatatgg     3300

cacgccgaat cctgtttttc aaatatatgc ttttggtggc taccatgcag gatttgaatt     3360

tgtcttttaa tttagcttag gaaagaacat cactgggcga gcggtaaatc ctaaagaagg     3420

tgataaatgt cagtagtttc ttattaaata ttctaatttt aggttcccaa accttcagga     3480

aatatatctt aatgcagaca aacaaacata aaacttcttt agtacttaca tcaggaaatt     3540

tggggcagat tttagagggg ggaaattata ggaggaaaga agttcacatc agaacagaca     3600

atcacagcaa tgctctattc cttagaaatt agtgccacaa ataagttaca tctacaaaca     3660

ggtggtaaaa attctttctg gcccagttaa tttgcacaga acttttctca gtttggtatt     3720

ttttactgct tggagatcca gaagagaatt agaaacaaca tagcaaatta aaataggttt     3780

gtcaataata gagctcagac acctgtgtgc tgtagattca catacaggcc gtgaacctaa     3840

gtggggaaaa tcctacctat ccaccttctg gctagattac ctagcttagt gaaaagatag     3900

ccaaataatt ggcatgtgaa ttatttcctg cttattcata ataaataatg actgtcta       3958


<210>  577
<211>  977
<212>  DNA
<213>  homo sapiens

<400>  577
gggctccgcg cccggccagc ctgaggtggg gtcggtgccc ccggcggcac ggcgctgggg       60

aggcgatggc gccggccgcg tccaggctgc gggccgaagc cgggctcggg gcgctgccgc      120

ggcgggcgct cgcccagtac ctgctcttcc tgcggctcta cccggtgctc accaaggcgg      180

ccaccagtgg cattttgtca gcacttggga acttcctggc ccagatgatt gagaagaagc      240

ggaaaaaaga aaactctaga agtctggatg tcggtgggcc tctgagatat gccgtttacg      300

ggttcttctt cacagggccg ctgagtcact tcttctactt cttcatggaa cattggatcc      360

ctcctgaggt ccccctggca gggctcagga ggcttctcct ggaccgcctc gtctttgcac      420

cggccttcct catgttgttc ttcctcatca tgaactttct ggaggggaaa gacgcctcag      480

ccttcgccgc caagatgagg gggggcttct ggccggcgct gaggatgaac tggcgggtgt      540

ggacgccact acagttcatc aacatcaact acgtccctct gaagttccgg gtgctcttcg      600

ccaacctggc agctctgttc tggtatgcct acctggcctc cttggggaag tgacgaccgc      660

tgggagaaca tcaggtgcac tgtggacgtg ggtctggggg tctcacccgc ccagcgagag      720

cagaaccaat ccagtcagga tgtcactgac tctaaatcag gtgattcaag atgcccaaaa      780

atgatggata gagaaacaga aatctctgaa tgtcagaacc ctgtctttta aaaaggcagt      840

cgctgccttc aggtggtgct gccccagaaa cttaaaattt agtcgaggca gtttcaattg      900

ttactgtgga ccgaattagg atcacaataa acgataatgc aggttcttca atggtgaaaa      960

aaaaaaaaaa aaaaaaa                                                     977


<210>  578
<211>  2515
<212>  DNA
<213>  homo sapiens

<400>  578
ctacaggcac tgggaacttg caagcagcca gggaacgctg aaaatagcac gtctttttct       60

ttctttgtgt tcaaaactat tttctttctt caccagattt tgttttcctc cccccgctgc      120

agttgtttcc cattagtaac tcgatctctc agagcagtaa gattcgcctt ctacgcctct      180

ttttccctcc gcccgaattg tttgttttct gcacatctcc ttcagggagc cgctgaggct      240

tccccccaac tcttcccagt tctttttgct tcccctcggc cccccaagca gaccgatttc      300

cactccatct gtttcttctc ctcctttctc tccctctttc cctccatcct cgagcgtctc      360

tgcgctccta cagggcagcc ctctctggtc ccttgcctcc ttcactcgga tgagctgaaa      420

gccccgggcg tgtgtatatg gaaatagtgg ggtgccgagc agaagacaac tcgtgtcctt      480

tccgcccccc agccatgctc tttcacggga tctccggagg ccacatccaa ggcatcatgg      540

aggagatgga gcgcagatcc aagactgagg cccgtctggc caaaggcgcc cagctcaacg      600

gccgcgacgc gggcatgccc ccgctcagcc cggagaagcc cgccctgtgc gccggctgcg      660

ggggcaagat ctcggacagg tactatctgc tggctgtgga caaacagtgg catctgagat      720

gcctgaagtg ctgtgaatgt aagctggccc tcgagtccga gctcacctgc tttgccaagg      780

acggtagcat ttactgcaag gaggattact acagaaggtt ctctgtgcag agatgtgccc      840

gctgccacct tggcatttcc gcctcggaga tggtcatgcg cgcccgagac tctgtctacc      900

acctgagctg cttcacctgc tccacttgca acaagactct gaccacgggc gaccatttcg      960

gcatgaagga cagcctggtg tactgccgcg cccacttcga gaccctcttg caaggagagt     1020

atccaccgca gctgagctac acggagctgg cggccaagag cggcggcctg gccctgcctt     1080

acttcaacgg tacgggcacc gtgcagaaag ggcggccccg gaagcggaag agcccagcgc     1140

tgggagtgga catcgtcaat tacaactcag gttgtaatga gaatgaggca gaccacttgg     1200

accgggacca gcagccttat ccaccctcgc agaagaccaa gcgcatgcga acctctttca     1260

agcatcacca gctccggacc atgaaatcct actttgccat caaccacaac ccggatgcca     1320

aggacctcaa gcagcttgcc cagaaaacag gtctgaccaa aagagttttg caggtttggt     1380

tccaaaacgc acgagccaaa ttcagaagga accttttgcg gcaggagaat gggggtgttg     1440

ataaagctga cggcacgtcg cttccggccc cgccctcagc agacagcgga gctctcactc     1500

cacccggcac tgcgaccact ttaacagacc tgaccaatcc cactatcact gtagtgacat     1560

ccgtgacctc taacatggac agccacgaat ccggaagccc ctcacaaact accttaacaa     1620

accttttcta acattggttt ttttttttta gtttttaaat tcttcctctt ctttttatta     1680

ttattctaat tattattatt ttattattta caagactttt tttttcttct aacccacaag     1740

atatttgggg aataaaaata acagcttggt gtgtagcatc tgcagccact tggcaaatga     1800

gtttacagta ttgtctcctt taagtgaata tattttgtct acaaagtgta tttggattta     1860

aaaaaattaa ttaggtcttt cagttggtaa ggagagtttt tgaataattc taataagtgc     1920

ctcttaaaat tgtatgttac ttatttccag aatctcgaag aaaaaagaaa aaagagtggt     1980

attattatgg gcaaataatc atattcccac ttaaatgatt aggttaataa agaaccagat     2040

aattaattag ttacttttta aatcttgcaa ttgtatgtgt gattatggag ttttgaaaac     2100

gttacatttt ttaaatctta aaactgaaaa cttgttttta gtatttctat ttcttacctg     2160

aactgttaat tcaagtgagg aatatgatga aataaaagca ttaactacag acattttaaa     2220

tagtaatgat taattaggtg agaaatctat tacaggaatg tgacttttcc ttctcttagg     2280

ggtgtacaac tctaaaaact ttttacttgg ttatttgttt ttcaacattt gaaaaatact     2340

taagctccct atgtatccat gaaaattccg cattgatttt gacattccat acttttaacc     2400

tcctaaagct aaaaacaata gctcggaaac cattctttct agttactttt tttcccaggg     2460

aaaatggaaa taagcaaaat ataatgtttt aagaagtaaa aaaatcaata taatt          2515


<210>  579
<211>  2960
<212>  DNA
<213>  homo sapiens

<400>  579
gcagtaccca agcgagccat ttaacatggc ggaggatgtt tcctcagcgg ccccgagccc       60

gcggggctgt gcggatggta gggatgccga ccctactgag gagcagatgg cagaaacaga      120

gagaaacgac gaggagcagt tcgaatgcca ggaactgctc gagtgccagg tgcaggtggg      180

ggcccccgag gaggaggagg aggaggagga ggacgcgggc ctggtggccg aggccgaggc      240

cgtggctgcc ggctggatgc tcgatttcct ctgcctctct ctttgccgag ctttccgcga      300

cggccgctcc gaggacttcc gcaggacccg caacagcgca gaggctatta ttcatggact      360

atccagtcta acagcttgcc agttgagaac gatatacata tgtcagtttt tgacaagaat      420

tgcagcagga aaaacccttg atgcacagtt tgaaaatgat gaacgaatta cacccttgga      480

atcagccctg atgatttggg gttcaattga aaaggaacat gacaaacttc atgaagaaat      540

acagaattta attaaaattc aggctatagc tgtttgtatg gaaaatggca actttaaaga      600

agcagaagaa gtctttgaaa gaatatttgg tgatccaaat tctcatatgc ctttcaaaag      660

caaattgctt atgataatct ctcagaaaga tacatttcat tccttttttc aacacttcag      720

ctacaaccac atgatggaga aaattaagag ttatgtgaat tatgtgctaa gtgaaaaatc      780

atcaaccttt ctaatgaagg cagcggcaaa agtagtagaa agcaaaagga caagaacaat      840

aacttctcaa gataaaccta gtggtaatga tgttgaaatg gaaactgaag ctaatttgga      900

tacaagaaaa agtgttagtg acaaacagtc tgcggtaact gaatcctcag agggtacagt      960

atccttattg aggtctcaca agaatctttt cttatctaag ttgcaacatg gaacccagca     1020

acaagacctt aataagaaag aaagaagagt aggaactcct caaagtacaa aaaagaaaaa     1080

agaaagcaga agagccactg aaagcagaat acctgtttca aagagtcagc cggtaactcc     1140

tgaaaaacat cgagctagaa aaagacaggc atggctttgg gaagaagaca agaatttgag     1200

atctggcgtg aggaaatatg gagagggaaa ctggtctaaa atactgttgc attataaatt     1260

caacaaccgg acaagtgtca tgttaaaaga cagatggagg accatgaaga aactaaaact     1320

gatttcctca gacagcgaag actgattgtg tttgtaaaag cttgatgaaa ggacagttaa     1380

gtattttgat cactgcattt tgtttgaaac ttgtgtcatt gatgtaattt aaaacttttg     1440

tttaaagcat tacagtattt ttctgtgacc atcaattaat gagggtttgt gctaccagag     1500

ttaaagcata tgctatcatt gtattcttta agaaccttat tttgataaaa tgtaaatttg     1560

ttgaaccctg ccacatttag tatccccacc cccaaatcct gttccaatga aaaaattaaa     1620

acctgatacg aaaaaaaaaa aattccagtt aacctatttt gtgtctgtag gctgacctca     1680

accctgtaac gtaacccatt aaaatgaatt tctttttttt taagacagag tttctctctg     1740

ttgcccaggc tggagtgcag tggcgcaatt tcagctcact gcaacctctg cctcccaggt     1800

tcaagtgatt ctcctgcctc agcctcctga gtagctggga ttacaggcac acaccaccac     1860

gcccagctaa tttttgtatt tttagtagag gcggggtttc accatgctgg tcaggatgtt     1920

ctccaactcc tgacttcatg atccacccac ctcggcctcc caaagtgctg agattacaga     1980

cgtgagccac tgcgtcctgc ctaaaatgaa ttttctagat gattgaataa cagtagtcct     2040

ttgatagaag ataatgactt ggtttatggc cttaatatac tacttaatta cttaagatgt     2100

ttattaatag aatgataaat gtacagagta acctataagc atgacatact tttgctttca     2160

gtagtttcat gtaaagaaaa aaacttgaaa atagtaatac ctgagtaccc atgggaataa     2220

tagacactgg ggaggtaggg tggggagcgg gagcaagagc tgaaaaactt acctactggg     2280

gactgtgctc actacctggg tgacaggatc atacgtaccc caaacctcaa catcacacag     2340

tatactcagc taacaaacct gcccatgtgt ttcctgaatc taaaataaaa atcgaaataa     2400

tttttttaaa aaagaaaaag acaatagtat tacccatggg acaaaatttg tactattagc     2460

aagaatcatt ttgtgtctca tttagaaaca atttgacttt tgttccagtg tttaaacttt     2520

gacaaaaatg gttttgaata gatctttata acctgatgcc ataaatacaa gattctctga     2580

taccttcatt taatatatca atattgggcc taaaacagta ttctgtaaag cttaaattgg     2640

tattaactat gatcatcttg atgtctatga tagataataa acaaggtcat acatacctta     2700

ctaaacaatt ttggtttttc accaacattt tattctttaa aagatttaga ctaacagaat     2760

tatttagcat ttcgagtcat gtgctttatt tagcaagtga gtaaaaatat tggaatattg     2820

aagtatttgc ataaaaaatc aaatggtggt gttttgtaat ctctattgta tttcctatta     2880

aggtttcata tattactttc ccattgttcc tgaatttgtt atcctatata taaacagaaa     2940

catggatgag taccatatac                                                 2960


<210>  580
<211>  3021
<212>  DNA
<213>  homo sapiens

<400>  580
gggcctactc tgccgccgcc gccgcccgcc cgctccagcc gccgccgccg ccgccaccgc       60

cctccaggct ccgggacccg gcccgcgcca ccgcccccgt gcgcgccccg ccgccgccgc      120

cttcgccttc gccttttgtt tcctccgctc cggcgccccc gccccggctc gcgctttgca      180

ggggacgcag cgcgcgcccc cagcgggccc gggaaaagcc gcggcgcgcg cgcgcgcctg      240

cgcggcggac ccctccttct cctccccgcg tgcgcgtgcc cttcttggct gcgcgccggc      300

gccgcctggc gggcgggagg ggaggtggca ggcgcgtttg caggaggggc gcacctcttc      360

gctcgcgcac ccccccggaa ggtagaccgg gaaggggagg cgggcgggcg gagaggagag      420

agtggcgcgc agtccagcga gggcgggggt tggctatgtg gggggtggtg caccccgcag      480

tctagacagt ctgatccggg ctgggggcgt gtacactcgg cgcacctgcg agactacaga      540

gcctcgggcc ggcacgtgtg gggagtgtgg acacgtctgc tgcgccccgc ttctcgctgc      600

tgaggggaag ggagggggcg ggcaggtgca gcggccgggc tagtgggagg gggcggcggc      660

catggagcgg gtgaacgacg cttcgtgcgg cccgtctggc tgctacacat accaggtgag      720

cagacacagc acggagatgc tgcacaacct gaaccagcag cgcaaaaacg gcgggcgctt      780

ctgcgacgtg ctcttgcggg taggcgacga gagcttccca gcgcaccgcg ccgtgctggc      840

cgcctgcagc gagtactttg agtcggtgtt cagcgcccag ttgggcgacg gcggagctgc      900

ggacgggggt ccggctgatg tagggggcgc gacggcagca ccaggcggcg gggccggggg      960

cagccgggag ctggagatgc acactatcag ctccaaggta tttggggaca ttctggactt     1020

cgcctacact tcccgcatcg tggtgcgctt ggagagcttt cccgaactca tgacggccgc     1080

caagttcctg ctgatgaggt cggttatcga gatctgccag gaagtcatca aacagtccaa     1140

cgtacagatc ctggtacccc ctgcccgcgc cgatataatg ctctttcgcc cccctgggac     1200

ctcggacttg ggcttccctt tggacatgac caacggggca gccttggcag ccaacagcaa     1260

tggcatcgcc ggcagcatgc agccagagga ggaggcagct cgggcggctg gtgcagccat     1320

tgcaggccaa gcctctttgc ctgtgttacc tggggtggac cgcttgccca tggtggctgg     1380

acccctatcc ccccaactgc tgacttcccc attccccagt gtggcatcca gtgcccctcc     1440

cctgactggc aagcgaggcc ggggccgccc aaggaaggcc aacctgctgg actcaatgtt     1500

tgggtcccca gggggcctga gggaggcagg catccttcca tgcggtctat gtggtaaggt     1560

gttcactgat gccaaccggc tccggcagca cgaggcccag cacggtgtca ccagcctcca     1620

gctgggctac atcgaccttc ctcctccgag gctgggtgag aatgggctac ccatctctga     1680

agaccccgac ggcccccgaa agaggagccg gaccaggaag caggtggctt gtgagatctg     1740

cggcaagatc ttccgtgatg tgtatcatct taaccggcac aagctgtccc actctgggga     1800

gaagccctac tcctgccctg tgtgtgggtt gcggttcaag agaaaagacc gcatgtccta     1860

ccatgtgcgg tcccatgatg ggtccgtggg caagccttac atctgccaga gctgtgggaa     1920

aggcttctcc aggcctgatc acttgaacgg acatatcaag caggtgcaca cttctgagcg     1980

gcctcacaag tgtcaggtgt gggttgggag cagcagcggc ctgccgcccc tggaacctct     2040

tcctagcgac ctgccatcat gggactttgc ccagcctgct ttgtggaggt cgtcccattc     2100

ggttcctgac accgcctttt ccctttctct aaaaaaatca ttcccagccc ttgaaaacct     2160

gggcccagca cactccagca acactctctt ctgcccagcc ccgccgggat atctgaggca     2220

gggctggacc accccagagg gcagcagggc ctttacccag tggcctgttg gctagcctgg     2280

gcctccctgg agagggttga cagtggaagg gaacaggagg ggcatttggc ctgagacccc     2340

tgcttttggg agaggctagc agggtggttc ctgcccagca tgcccagctc ctccctgggt     2400

gactcggagt ctttcccatg tcagagcccc caaatggggg tagcaaggag cacctttctg     2460

gaacccccta tagcatccaa gtttctttct gggctctctt gccttttccc ccctttcaca     2520

gatggcaccc ctgggcatct gtccttgcct aggtgatttt ggaggttggt gccttcctgg     2580

gaactagcca ccagcttatc tgcttccctt cccctggcat cacttcccat aggcctgggg     2640

tttctagact ggggcctggc cacccctttc cccactccac gagtgagtcg gcctccagag     2700

aagactggca caattccaac tagagtcaac ccatgctgcc ctctgccctt cccactcaga     2760

tctagatcct gctttcattt ctggctagtg aagtagactt ttgtgttttt gaggtttatt     2820

agcaggtctg ctcaggaacc aaactaatga gtagctttat attgggccac cccaatatat     2880

ggctttgggg gctgaaaaag cagatgtaga ccccctccct cggatcctta ttggtgtgcc     2940

ctttagcact ccgcagactc tgcggggtga acaggagtga tgataaaatt tttcattcta     3000

aaaaaaaaaa aaaaaaaaaa a                                               3021


<210>  581
<211>  7190
<212>  DNA
<213>  homo sapiens

<400>  581
cttttagttt ctcttctttc taaagaaggc tcgcggagcc cggctggaga acctcaccct       60

cgccgagcct agaaccgaga gggggccacc ccaggcggtc accagcagat ttgcccgcgc      120

gttctctttc tttccaccca gttgcccttg cggccggctg taaacctgcc actaggaccc      180

ggtcggtgag atctagcctc ttgacctgag agccgagagt ggatcgctgg gctgggctaa      240

cggcgacgga gagcgcgccc tcgctgactc cgggcgcgcc cagcagtagc accgcccgcg      300

cccgcccctg gacacttgta agtttcgatt tccgatttcc gcggaaccga gtcccgcgcc      360

gcggcagagc cagcacagcc agcgcgccat ggcggacccg gaggtgtgct gcttcatcac      420

caaaatcctg tgcgcccacg ggggccgcat ggccctggac gcgctgctcc aggagatcgc      480

gctgtctgag ccgcagctct gtgaggtgct gcaggtggcc gggcccgacc gctttgtggt      540

gttggagacc ggcggcgagg ccgggatcac ccgatcggtg gtggccacca ctcgagcccg      600

ggtctgccgt cgcaagtact gccagagacc ctgcgataac ctgcatctct gcaaactcaa      660

cttgctgggc cggtgcaact attcgcagtc cgagcggaat ttatgcaaat attctcatga      720

ggttctctca gaagagaact tcaaagtcct gaaaaatcac gaactctctg gactgaacaa      780

agaggaatta gcagtgctcc tcctccaaag tgatcctttt tttatgcccg agatatgcaa      840

aagttataag ggagagggtc ggcagcagat ttgtaaccag cagccaccgt gttcaagact      900

ccacatctgt gaccacttca cccgagggaa ctgtcgtttt cccaactgcc tccggtccca      960

taacctgatg gacagaaagg tgctggccat catgagggag cacgggctga accccgacgt     1020

ggtccagaac atccaggaca tctgcaacag caagcacatg cagaagaatc ccccagggcc     1080

cagagctcct tcttcacatc gtagaaacat ggcatatagg gctagaagca agagtagaga     1140

tcggttcttt cagggcagcc aagaatttct tgcgtctgct tcagcgtctg ctgagaggtc     1200

ctgcacacct agtccagatc agatcagcca cagggcttcc ctggaggacg cgcctgtgga     1260

cgatctcacc cgcaagttca cgtatctggg gagtcaggat cgcgctcggc ctccctcagg     1320

ctcgtccaag gctactgatc ttggaggaac aagtcaggcc gggacaagcc agaggttttt     1380

agagaacggc agtcaagagg acctcttgca tggaaatcca ggcagcactt accttgcttc     1440

caattcaaca tcagccccca actggaagag cctcacatcc tggacgaatg accaaggcgc     1500

caggagaaag actgtgtttt ctcccacgct acctgccgcc cgctcttctc ttggctctct     1560

gcaaacacct gaagctgtga ccaccagaaa gggcacaggc ttgctttcct cagactacag     1620

gatcatcaat ggcaaaagtg gaactcagga catccagcct ggccctcttt ttaataataa     1680

tgctgatgga gtggccacag atataacttc taccagatcc ttaaattaca aaagcactag     1740

cagcggtcac agagaaatat catcacctag gattcaggat gctggacctg cttcccgaga     1800

tgtccaggcc actggcagaa tcgcagatga tgctgaccca agagtagcac ttgttaacga     1860

ttctttatct gatgtcacaa gtaccacatc ttctagggtg gatgatcatg actcagagga     1920

aatttgtctt gaccatctgt gtaagggttg tccgcttaat ggtagctgca gcaaagtcca     1980

cttccatctg ccttaccggt ggcagatgct tattggtaaa acctggacgg actttgagca     2040

catggagacg atcgagaaag gctactgtaa ccccggaatc cacctctgtt ctgtaggaag     2100

ttatacaatc aattttcggg taatgagttg tgattccttt cccatccgac gcctctccac     2160

tccttcttct gtcaccaagc cagccaattc tgtcttcacc accaaatgga tttggtattg     2220

gaagaatgaa tctggcacat ggattcagta tggagaagag aaagacaaac ggaaaaattc     2280

aaacgtcgac tcttcatacc tggagtctct ctatcaatcc tgtccgaggg gagttgtgcc     2340

atttcaggcg ggctcacgga actatgagct gagtttccaa gggatgattc agacaaacat     2400

agcttccaaa actcaaaagg atgtcatcag aagaccaaca tttgtgcctc agtggtatgt     2460

gcagcagatg aagagagggc cagaccatca gccagcaaag acctcgtcag tgtctttaac     2520

tgcgaccttt cgtcctcagg aggacttttg cttcctatcc tcaaagaaat ataagttgtc     2580

agagatccat cacctacatc cagaatatgt cagagtaagt gagcatttta aagcttccat     2640

gaaaaatttc aagattgaaa agataaagaa gatcgagaac tcagagctcc tggataaatt     2700

tacatggaag aaatcgcaga tgaaggaaga aggaaaactc ctattttatg cgacaagccg     2760

tgcctatgtg gaatctatct gttcgaataa ttttgacagt ttcctacatg aaactcatga     2820

aaacaaatac ggaaaaggaa tttactttgc aaaagatgcc atctattccc acaaaaattg     2880

cccgtatgat gccaaaaacg tcgttatgtt tgtagcccaa gttctggttg gaaagtttac     2940

tgaaggaaat ataacgtaca cgagccctcc tccacagttc gacagctgtg tggataccag     3000

atcgaatccc tccgtttttg tcatctttca gaaagatcag gtttacccac aatatgtgat     3060

tgaatatact gaagacaaag cctgcgtgat tagttagaac cgatgaatac agcgtcagaa     3120

ggatgccata accattctgt tcctttacag aactaaattg ccgcagacag gagttaaagt     3180

tttatatttt cctgctcagt tatctaatgt cttagatcag tggtccccaa attttgctac     3240

atattagaat catctgggag gttttaaaca aattctgatg cccaggttgc accccatgcc     3300

aatgaaatca tttctgggcg tcagcgccag gcagttgtat tttttttttt tttttttttt     3360

ttgagactga atctcactcc atcgtccagg ctggagtgca gtggcgcgat ctcggctcac     3420

tgcaacctct gcctcccggg ttcaagcaat tctcctgcct cagcctcccg agtagctgga     3480

actacaggca cacactgccg cgcccagcta attttttgta ttttttagta gagacagggt     3540

ttcactgtgt tgcccaggct ggtctcaaac tcctgagctc aggcaatctg cccgccttgg     3600

cctcccaaag tgctaggatt acaggtatga gccaccatgc ccggctggca gttgtatttt     3660

ttaaagccct tctgatgatt ccaatgtgtt ggaaagttta ccttgtctca gatgtaactg     3720

gtaaaggctg atttctaaat tttctgtaat tgcagcaacc tttctctcct gtctaccctt     3780

ttagtttact gtatgccatg gttttgtttt ggttacattg aaagaaagtt aatttggaaa     3840

atttgggaga aatctaatca tgcctattaa ggatgtaaga cattacagcc ttagaagaaa     3900

gattgtgaaa agctggggag aaaatgctta aggacatgct aggggaaaaa aaagtaaaat     3960

tgaagtgcta ttgcagacat ggctgcagta ctgtacctta tcattctgat gaaactgatt     4020

tggagcaccc ttttctttat cgctacattt atttagggga caaactccat ccaggttgac     4080

tctctctgga atgcggtaat aagagctggc aagtaaggct cagagagaag caaccaactg     4140

gagttaattg cccatttggg ctctttgtat aattatggca aagtagacat ttatgttcta     4200

attaatatga ttacagagaa ggctttttct caggtcaggc ttttcatgaa agtattttga     4260

gaacaatgaa ttgcaataac cagcttcaca caagcataac tgataaacgc gagtgctatt     4320

gtagtcttgg caagtgagcc aagaacctag gagcagggcc attcctactg aaggacgggc     4380

cccctacgga gatgaaattt gtttcctggt gagcacagaa tcagaacaaa gaacaatatc     4440

ccaaagaggc cctgtgtcta ccaggagctt ctttttccaa atgtaatgga ttatgtggaa     4500

ttgtagtgcc atcggttttt acttagagcc cttgacgtgc ttggaccaat atttccttcc     4560

ttcttatgaa ccaggttttt ccttctgatt ttcccttttc aacattcctt accagtcacc     4620

aaagtttcct gttataattt cttttagcag acaagttata agtcagattt aattagcatc     4680

agagttgatt ttatattagt cagattttgg atcatcacag agatctccac aactccttgg     4740

cttaaacagc tccaccggta aaaaaaaaaa aaaaaaaaaa aaaaaaaaat agttttttta     4800

gagtagagtt attttctggg agagttacta caaatgctta ttctcattga cttatttctt     4860

tcatggtaac tttcgttttg gagtgttcat tttctgaact tgaccctcac attgtagggg     4920

tgcagtttgt ccaactcttt ccaacagccc attagacacc actagctgga tatttcacag     4980

gcatctttga ttcaatatgt ccaaagtgga actctccatc tacctccctc acatgaacct     5040

gttcctctct caggatctgt atgtaagtga aaagcatcac catctaccca ttggctcaag     5100

cagaaatctg gaagtcatct ttgactcctt cctctccctc ctgataaaca tctaagcagt     5160

ttctaagtct agttttacct cttaaatatc tctgttccct tctaagttgt ttgctgtgtt     5220

ttcttcagag caagaaggtt atatttttta aaatttactt agtaatgcac attcaaaaca     5280

cacatcaagt cttcaggata aagttcaaaa ccgctgtcat ggccccatgt gatctctccc     5340

tcccctaccc ctctatcatt tagtttcttc tgcgcaagcc actctggctt cctttcagtt     5400

ttgtggttcc catttttagc tagttcagtg gttttcaatg ggcatttctg cctttttttt     5460

tctaaacgac aaatagaaat acatcttctt tattatcctc caaatccaat tcagaggtaa     5520

tatgctccac ctacacacaa ttttagaaat aaattaaaaa ttaaataaaa ctaatatgaa     5580

cataaagagg aaataaaagg tacctaactt gggcacagct gtaactgaag acctaatgaa     5640

gtagtcagat gcttacaact atttataatg catcaatttg aacttagaag gtaggagatc     5700

agatcatatg tgggaaaatg taaaagcagg gatatcagtg ggcattagaa taaaaactag     5760

ggatacaata acttctttgc atatgacaat acttatttgt atataagaga aagaacgaaa     5820

taacctttat tgaaataaag atactatgca agaaaatgta cagttgtcga agtggagaaa     5880

atgaggatat attcttgcag acgagctata ggtcatacat gaatgtctag tgagacattc     5940

aaaattcgta tagggtgcag agtaatttct tattgtgagg aactgtccaa tgtattgcaa     6000

gatgttctgc atacttggct ctcacatact aaatgctagt agcgccccca cccccacgcc     6060

cagtcacggt gacaaccaca aaccctatca gatctattca cctttttcag agcagatatt     6120

ttgtaacatt ctctttgctg acctgaaatg actcatagat aatacaatct acttacacac     6180

atgaatttct taaaaaaatc aatttaatgc cctaactctc ttattaagga gaaatagaaa     6240

agaagaaatt tataatgaaa agaagatgaa tttcattatg taaacgctca ggcatgacta     6300

cgctgtttga aacagacaga tgtttactct tccttgtaat gagtaggttt ggatttaaga     6360

gccgattaga ggctacttcc tgtaaacaag tacaggaaaa tgaaactaga cgggtggggg     6420

acactagaat gaaaaccagt gttagggtaa agacaaaaca gactatgtac ataatctgta     6480

tatgggaaaa gaaagagcga aattacctta cttaaggata ataggacaag acaaattaca     6540

gattgtctca gagaaaacaa atgagttact ctctcggaca agctgtaggt cctacctaaa     6600

tgtccagcag gacattagac agtcgtacag ggtacagaat aattcttcgt tgtgtggcac     6660

taacccacac actgcaggac atcgttctcc ctggctgcat ccactcagtg ctgggagtag     6720

tccccagtta ttatgaaacc accaataacc cactgaccac agtgagaacc actgattttt     6780

tccactgacc tactgaatat ctagcatcct tagattggct caactgttac tttcctaagg     6840

agtccttcta cagaataggt cagatcttgg cctcccaaac cccttatttt taaaatactt     6900

tgcgccttgc tttgataatt tgtattatgt atccaaactg aaattatctg ctttctgcat     6960

tagaatgtaa gccccctgag ggttgagtca gtctgtcttg tttgctgtgc cacgcctgat     7020

gcccagccca gcagcatgct ttgtacactg atatattggg taaattttgt tgaataaatt     7080

aagctcaact atttgtattt caatagttga gttgtattgc ttcctgttct tcaagcttaa     7140

tttgaactgt ctaataaaaa gaagtaatta aaaaaaaaaa aaaaaaaaaa                7190


<210>  582
<211>  6615
<212>  DNA
<213>  homo sapiens

<400>  582
agctccagcc gcactgcccc gatggctccc tacccctgtg gctgccacat cctgctgctg       60

ctcttctgct gcctggcggc tgcccgggcc aacctgctga acctgaactg gctttggttc      120

aataatgagg acaccagcca tgcagctacc acgatccctg agccccaggg gcccctgcct      180

gtgcagccca cagcagatac caccacacac gtgacccccc ggaatggttc cacagagcca      240

gcgacagccc ctggcagccc tgagccaccc tcagagctgc tggaagatgg ccaggacacc      300

cccacttctg ccgagagccc ggacgcgcca gaggagaaca ttgccggtgt cggagccgag      360

atcctgaacg tggccaaagg catccggagc ttcgtccagc tgtggaatga cactgtcccc      420

actgagagct tggccagggc ggaaaccctg gtcctggaga ctcctgtggg cccccttgcc      480

ctcgctgggc cttccagcac cccccaggag aatgggacca ctctctggcc cagccgtggc      540

attcctagct ctccgggcgc ccacacaacc gaggctggca ccttgcctgc acccacccca      600

tcgcctccct ccctgggcag gccctgggca ccactcacgg ggccctcagt gccaccacca      660

tcttcaggta gagcttctct ctcctccttg ctgggcgggg cccctccctg gggaagcctg      720

caggacccag acagccaagg actctcgccc gccgcagccg ctcccagcca gcagctccaa      780

cgccctgacg tccgcctgcg cacgccactt ctgcaccccc tggtgatggg ctccctgggc      840

aagcacgcgg ccccctccgc cttctcctct gggctcccgg gcgcactgtc tcaggtcgca      900

gtcaccactt taaccaggga cagcggtgct tgggtctccc acgtggctaa ctctgtgggg      960

ccgggtcttg ctaataactc tgccctgctc ggggctgacc ccgaggcccc cgccggtcgc     1020

tgcctgcccc tgccaccctc cctgccagtc tgcggccacc tgggcatctc acgcttctgg     1080

ctgcccaacc acctccacca cgagagcggc gagcaggtgc gggccggggc acgggcgtgg     1140

gggggcctgc tgcagacgca ctgccacccc ttcctcgcct ggttcttctg cctgctgctg     1200

gtccccccat gcggcagcgt cccgccgccc gccccgccac cctgctgcca gttctgcgag     1260

gccctgcagg atgcgtgttg gagccgcctg ggcgggggcc ggctgcccgt cgcctgtgcc     1320

tcgctcccga cccaggagga tgggtactgt gtgctcattg ggccggctgc agagcgcatc     1380

agcgaggagg tggggctgct gcagctcctt ggggaccccc cgccccagca ggtcacccag     1440

acggatgacc ccgacgtcgg gctggcctac gtctttgggc cagatgccaa cagtggccaa     1500

gtggcccggt accacttccc cagcctcttc ttccgtgact tctcactgct gttccacatc     1560

cggccagcca cagagggccc aggggtgctg ttcgccatca cggactcggc gcaggccatg     1620

gtcttgctgg gcgtgaagct ctctggggtg caggacgggc accaggacat ctccctgctc     1680

tacacagaac caggtgcagg ccagacccac acagccgcca gcttccggct ccccgccttc     1740

gtcggccagt ggacacactt agccctcagt gtggcaggtg gctttgtggc cctctacgtg     1800

gactgtgagg agttccagag aatgccgctt gctcggtcct cacggggcct ggagctggag     1860

cctggcgccg ggctcttcgt ggctcaggcg gggggagcgg accctgacaa gttccagggg     1920

gtgatcgctg agctgaaggt gcgcagggac ccccaggtga gccccatgca ctgcctggac     1980

gaggaaggcg atgactcaga tggggcatcc ggagactctg gcagcgggct cggggacgcc     2040

cgggagcttc tcagggagga gacgggcgcg gccctaaaac ccaggctccc cgcgccaccc     2100

cccgtcacca cgccaccctt ggctggaggc agcagcacgg aagattccag aagtgaagaa     2160

gtcgaggagc agaccacggt ggcttcgtta ggagctcaga cacttcctgg ctcagattct     2220

gtctccacgt gggacgggag tgtccggacc cctgggggcc gcgtgaaaga gggcggcctg     2280

aaggggcaga aaggggagcc aggtgttccg ggcccacctg gccgggcagg ccccccagga     2340

tccccatgcc tacctggtcc cccgggtctc ccgtgcccag tgagtcccct gggtcctgca     2400

ggcccagcgt tgcaaactgt ccccggacca caaggacccc cagggcctcc ggggagggac     2460

ggcacccctg gaagggacgg cgagccgggc gaccccggtg aagacggaaa gccgggcgac     2520

accgggccac aaggcttccc cgggactcca ggggacgtag gtcccaaggg cgacaaggga     2580

gaccctgggg ttggagagag agggccccca ggaccccaag ggcctccagg gcccccagga     2640

ccctccttca gacacgacaa gctgaccttc attgacatgg agggatctgg cttcgggggc     2700

gatctggagg ccctgcgggg tcctcgaggc ttccctggac ctcccggacc ccccggtgtc     2760

ccaggcctgc ccggcgagcc aggccgcttt ggggtgaaca gctccgacgt cccaggaccc     2820

gccggccttc ctggtgtgcc tgggcgcgag ggtccccccg ggtttcctgg cctcccggga     2880

cccccaggcc ctccgggaag agaggggccc ccaggaagga ctgggcagaa aggcagcctg     2940

ggtgaagcag gcgccccagg acataagggg agcaagggag cccccggtcc tgctggtgct     3000

cgtggggaga gcggcctggc aggagccccc ggacctgctg gaccaccagg cccccctggg     3060

ccccctgggc ccccaggacc aggactcccc gctggatttg atgacatgga aggctccggg     3120

gggcccttct ggtcaacagc ccgaagcgct gatgggccac agggacctcc cggcctgccg     3180

ggacttaagg gggatcctgg cgtgcctggg ctgccggggg cgaagggaga agttggagca     3240

gatggagtcc ccgggttccc cggcctccct ggcagagagg gcattgctgg gccccagggg     3300

ccaaagggag acagaggcag ccggggagaa aagggagatc cagggaagga cggagtcggg     3360

cagccgggcc tccctggccc ccccggaccc ccgggacctg tggtctacgt gtcggagcag     3420

gacggatccg tcctgagcgt gccgggacct gagggccggc cgggtttcgc aggctttccc     3480

ggacctgcag gacccaaggg caacctgggc tctaagggcg aacgaggctc cccgggaccc     3540

aagggtgaga agggtgaacc gggcagcatc ttcagccccg acggcggtgc cctgggccct     3600

gcccagaaag gagccaaggg agagccgggc ttccgaggac ccccgggtcc atacggacgg     3660

ccggggtaca agggagagat tggctttcct ggacggccgg gtcgccccgg gatgaacgga     3720

ttgaaaggag agaaagggga gccgggagat gccagccttg gatttggcat gaggggaatg     3780

cccggccccc caggacctcc agggccccca ggccctccag ggactcctgt ttacgacagc     3840

aatgtgtttg ctgagtccag ccgccccggg cctccaggat tgccagggaa tcagggccct     3900

ccaggaccca agggcgccaa aggagaagtg ggcccccccg gaccaccagg gcagtttccg     3960

tttgactttc ttcagttgga ggctgaaatg aagggggaga agggagaccg aggtgatgca     4020

ggacagaaag gcgaaagggg ggagcccggg ggcggcggtt tcttcggctc cagcctgccc     4080

ggcccccccg gccccccagg cccacgtggc taccctggga ttccaggtcc caagggagag     4140

agcatccggg gccagcccgg cccacctgga cctcagggac cccccggcat cggctacgag     4200

gggcgccagg gccctcccgg ccccccaggc cccccagggc ccccttcatt tcctggccct     4260

cacaggcaga ctatcagcgt tcccggccct ccgggccccc ctgggccccc tgggccccct     4320

ggaaccatgg gcgcctcctc aggggtgagg ctctgggcta cacgccaggc catgctgggc     4380

caggtgcacg aggttcccga gggctggctc atcttcgtgg ccgagcagga ggagctctac     4440

gtccgcgtgc agaacgggtt ccggaaggtc cagctggagg cccggacacc actcccacga     4500

gggacggaca atgaagtggc cgccttgcag ccccccgtgg tgcagctgca cgacagcaac     4560

ccctacccgc ggcgggagca cccccacccc accgcgcggc cctggcgggc agatgacatc     4620

ctggccagcc cccctcgcct gcccgagccc cagccctacc ccggagcccc gcaccacagc     4680

tcctacgtgc acctgcggcc ggcgcgaccc acaagcccac ccgcccacag ccaccgcgac     4740

ttccagccgg tgctccacct ggttgcgctc aacagccccc tgtcaggcgg catgcggggc     4800

atccgcgggg ccgacttcca gtgcttccag caggcgcggg ccgtggggct ggcgggcacc     4860

ttccgcgcct tcctgtcctc gcgcctgcag gacctgtaca gcatcgtgcg ccgtgccgac     4920

cgcgcagccg tgcccatcgt caacctcaag gacgagctgc tgtttcccag ctgggaggct     4980

ctgttctcag gctctgaggg tccgctgaag cccggggcac gcatcttctc ctttgacggc     5040

aaggacgtcc tgaggcaccc cacctggccc cagaagagcg tgtggcatgg ctcggacccc     5100

aacgggcgca ggctgaccga gagctactgt gagacgtggc ggacggaggc tccctcggcc     5160

acgggccagg cctcctcgct gctggggggc aggctcctgg ggcagagtgc cgcgagctgc     5220

catcacgcct acatcgtgct ctgcattgag aacagcttca tgactgcctc caagtagcca     5280

ccgcctggat gcggatggcc ggagaggacc ggcggctcgg aggaagcccc caccgtgggc     5340

agggagcggc cggccagccc ctggccccag gacctggctg ccatactttc ctgtatagtt     5400

cacgtttcat gtaatcctca agaaataaaa ggaagccaaa gagtgtattt ttttaaaagt     5460

ttaaaacaga agcctgatgc tgacattcac ctgccccaac tctcccctga cctgtgagcc     5520

cagctgggtc aggcagggtg cagtatcatg ccctgtgcaa cctcttggcc tgatcagacc     5580

acggctcgat ttctccagga tttcctgctt tgggaagccg tgctcgcccc agcaggtgct     5640

gacttcatct cccacctagc agcaccgttc tgtgcacaaa acccagacct gttagcagac     5700

aggccccgtg aggcaatggg agctgaggcc acactcagca caaggccatc tgggctcctc     5760

cagggtgtgt gctcgccctg cggtagatgg gagggaggct caggtccctg gggctagggg     5820

gagccccttc tgctcagctc tgggccattc tccacagcaa ccccaggctg aagcaggttc     5880

ccaagctcag aggcgcactg tgacccccag ctccggcctg tcctccaaca ccaagcacag     5940

cagcctgggg ctggcctccc aaatgagcca tgagatgata catccaaagc agacagctcc     6000

accctggccg agtccaagct gggagattca agggacccat gagttggggt ctggcagcct     6060

cccatccagg gcccccatct catgcccctg gctgggacgt ggctcagcca gcacttgtcc     6120

agctgagcgc caggatggaa cacggccaca tcaaagaggc tgaggctggc acaggacatg     6180

cggtagccag cacacagggc agtgagggag ggctgtcatc tgtgcactgc ccatggacag     6240

gctggctcca gatgcagggc agtcattggc tgtctcctag gaaacccata tccttaccct     6300

ccttgggact gaaggggaac cccggggtgc ccacaggccg ccctgcgggt gaacaaagca     6360

gccacgaggt gcaacaaggt cctctgtcag tcacagccac ccctgagatc cggcaacatc     6420

aacccgagtc attcgttctg tggagggaca agtggactca gggcagcgcc aggctgacca     6480

cagcacagcc aacacgcacc tgcctcagga ctgcgacgaa accggtgggg ctggttctgt     6540

aattgtgtgt gatgtgaagc caattcagac aggcaaataa aagtgacctt ttacactgaa     6600

aaaaaaaaaa aaaaa                                                      6615


<210>  583
<211>  8393
<212>  DNA
<213>  homo sapiens

<400>  583
agtagcacgg gcagctcgcg cgctggagga gggaggcgga aggacagcgc tgcgccacca       60

cccggaggag ggagcgcggt agctgcaggc aggggaggga gaggaaagaa aaggaaggac      120

ggctcccaga cagagagtgg gagaaaccgg ggagcagcgg gagcagcagg tccgggggga      180

gctgttccgc tgcgctgccc tcgttattca cacggacgct gcggagcttc ccagggctgc      240

ttccctgtcc ccctgggtgg aggctgccgt ctaaacctga ctccagagtt taagatgcaa      300

tggccagaag acatgaacgt gtcactagaa ggatgtggac atgggctccg ggactgttga      360

tgatgactgt ggtgttttgg ggtcatcagg ggaatggaca aggccaagga tcgcgtcttc      420

gccaggagga ctttcccccg cggattgtgg agcatccttc cgatgtcatc gtctctaagg      480

gcgagcccac gactctgaac tgcaaggcgg agggccggcc aacgcccacc attgagtggt      540

acaaagatgg ggagcgagtg gagactgaca aggacgatcc ccggtcccac aggatgcttc      600

tgcccagcgg atccttattc ttcttgcgca tcgtgcacgg gcgcaggagt aaacctgatg      660

aaggaagcta cgtttgtgtt gcgaggaact atcttggtga agcagtgagt cgaaatgcgt      720

ctctggaagt ggcattgtta cgagatgact tccgacaaaa ccccacagat gttgtagtgg      780

cagctggaga gcctgcaatc ctggagtgcc agcctccccg gggacaccca gaacccacca      840

tctactggaa aaaagacaaa gttcgaattg atgacaagga agaaagaata agtatccgtg      900

gtggaaaact gatgatctcc aataccagga aaagtgatgc agggatgtat acttgtgttg      960

gtaccaatat ggtgggagaa agggacagtg acccagcaga gctgactgtc tttgaacgac     1020

ccacatttct caggaggcca attaaccagg tggtactgga ggaagaagct gtagaatttc     1080

gttgtcaagt ccaaggagat cctcaaccaa ctgtgaggtg gaaaaaggat gatgcagact     1140

tgccaagagg aaggtatgac atcaaagacg attacacact aagaattaaa aagaccatga     1200

gtacagatga aggcacctat atgtgtattg ctgagaatcg ggttggaaaa atggaagcct     1260

ctgctacact caccgtccga gctcccccac agtttgtggt tcggccaaga gatcagattg     1320

ttgctcaagg tcgaacagtg acatttccct gtgaaactaa aggaaaccca cagccagctg     1380

ttttttggca gaaagaaggc agccagaacc tacttttccc aaaccaaccc cagcagccca     1440

acagtagatg ctcagtgtca ccaactggag acctcacaat caccaacatt caacgttccg     1500

acgcgggtta ctacatctgc caggctttaa ctgtggcagg aagcatttta gcaaaagctc     1560

aactggaggt tactgatgtt ttgacagata gacctccacc tataattcta caaggcccag     1620

ccaaccaaac gctggcagtg gatggtacag cgttactgaa atgtaaagcc actggtgatc     1680

ctcttcctgt aattagctgg ttaaaggagg gatttacttt tccgggtaga gatccaagag     1740

caacaattca agagcaaggc acactgcaga ttaagaattt acggatttct gatactggca     1800

cttatacttg tgtggctaca agttcaagtg gagagacttc ctggagtgca gtgctggatg     1860

tgacagagtc tggagcaaca atcagtaaaa actatgattt aagtgacctg ccagggccac     1920

catccaaacc gcaggtcact gatgttacta agaacagtgt caccttgtcc tggcagccag     1980

gtacccctgg aacccttcca gcaagtgcat atatcattga ggctttcagc caatcagtga     2040

gcaacagctg gcagaccgtg gcaaaccatg taaagaccac cctctatact gtaagaggac     2100

tgcggcccaa tacaatctac ttattcatgg tcagagcgat caacccccaa ggtctcagtg     2160

acccaagtcc catgtcagat cctgtgcgca cacaagatat cagcccacca gcacaaggag     2220

tggaccacag gcaagtgcag aaagagctag gagatgtcct tgtccgtctt cataatccag     2280

ttgtgctgac tcccaccacg gttcaggtca catggacggt tgatcgccaa ccccagttta     2340

tccaaggcta ccgagtgatg tatcgtcaga cttcaggtct gcaggcgaca tcttcgtggc     2400

agaatttaga tgccaaagtc ccgactgaac gaagtgctgt cttagtcaac ctgaaaaagg     2460

gggtgactta tgaaattaaa gtacggccat attttaatga gttccaagga atggatagtg     2520

aatctaaaac ggttcgtact actgaagaag ccccaagtgc cccaccacag tctgtcactg     2580

tactgacagt tggaagctac aatagcacaa gtattagtgt ttcctgggat cctcctcctc     2640

cagatcacca gaatggaatt atccaagaat acaagatctg gtgtctagga aatgaaacgc     2700

gattccatat caacaaaact gtggatgcag ccattcggtc cgtaataatt ggtggattat     2760

tcccaggtat tcaataccgg gtagaggttg cagctagtac cagtgcaggg gttggagtaa     2820

agagtgagcc acagccaata ataatcggga gacgcaatga agttgtcatt actgaaaaca     2880

ataacagcat aactgagcaa atcactgatg tggtgaagca accagccttt atagctggta     2940

ttggtggtgc ctgctgggta attctgatgg gttttagcat atggttgtat tggcgaagaa     3000

agaagaggaa gggactcagt aattatgctg ttacgtttca aagaggagat ggaggactaa     3060

tgagcaatgg aagccgtcca ggtcttctca atgctggtga tcccagctat ccatggcttg     3120

ctgattcttg gccagccacg agcttgccag taaataatag caacagtggc ccaaatgaga     3180

ttggaaattt tggccgtgga gatgtgctgc caccagttcc aggccaaggg gataaaacag     3240

caacgatgct ctcagatgga gccatttata gtagcattga cttcactacc aaaaccagtt     3300

acaacagttc cagccaaata acacaggcta ccccatatgc cacgacacag atcttgcatt     3360

ccaacagcat acatgaattg gctgtcgatc tgcctgatcc acaatggaaa agctcaattc     3420

agcaaaaaac agatctgatg ggatttggtt attctctacc tgatcagaac aaaggtaaca     3480

atggtgggaa aggtggaaaa aagaagaaaa ataaaaactc ttctaaacca cagaaaaaca     3540

atggatccac ttgggccaat gtccctctac ctcccccccc agtccagccc cttcctggca     3600

cggagctgga acactatgca gtggaacaac aagaaaatgg ctatgacagt gatagctggt     3660

gcccaccatt gccagtacaa acttacttac accaaggtct ggaagatgaa ctggaagaag     3720

atgatgatag ggtcccaaca cctcctgttc gaggcgtggc ttcttctcct gctatctcct     3780

ttggacagca gtccactgca actcttactc catccccacg ggaagagatg caacccatgc     3840

tgcaggctca cctggatgag ttgacaagag cctatcagtt tgatatagca aaacaaacat     3900

ggcacattca aagcaataat caacctccac agcctccagt tccaccgtta ggttatgtgt     3960

ctggagcctt gatttctgat ttggaaacgg atgttgcaga tgatgatgcc gacgacgaag     4020

aggaagcttt agaaatcccc aggcccctga gagcactgga ccagactcct ggatccagca     4080

tggacaatct agacagctct gtgacaggaa aagcctttac ctcctctcaa agacctcgac     4140

ctaccagccc attttctact gacagtaaca ccagtgcagc cctgagtcaa agtcagaggc     4200

ctcggcccac taaaaaacac aagggagggc ggatggacca acaaccagca ttgcctcatc     4260

gaagggaagg aatgacagat gaggaggcct tggtgcccta tagcaagccc agtttcccat     4320

ctccaggtgg ccacagctca tcaggaacag cttcttctaa gggatccact ggacctagga     4380

aaaccgaggt gttgagagca ggccaccagc gcaatgccag cgaccttctt gacataggat     4440

atatgggctc caacagtcaa ggacagttta caggtgaatt atagtaaatg agaggagaca     4500

tacaaagctg ctctgaagga ccatcaggtc cggactcatg gaagtgatga ctctaaacag     4560

tgcaatgaac aatttattta tgtactatta aaagaactgt aaatgcaatg taaagacaca     4620

cagccacaca tatcccacag atattttcat tgtgttcttc tcttaagtac accacccacc     4680

ttaactcttt cttgtcagga gtatataaaa aagaaagaaa acaaaactcg ccctacagga     4740

agaaaaggat tctcctctgt atataatttc ttttgtgcat tgctatgcaa gctcactctt     4800

tttagctctg ctcatattat tgtctgttct tattggtctg ttgtactata tgtgaattaa     4860

taggctgtgg tgccatatat taacttttaa ttgtgtaact tttatgttta aattttgcac     4920

tgcaatttta tttggtgata agcacaaatc tctactcctc atgacatgaa gaaaaagact     4980

gaatgtgaag ggagtttctg tactgtaagc tagattggat aatgatggct gtaacaaatc     5040

atgttagatg gttttcagtt ggggtgtaga aataggaaga tgcaaaggaa caatggtgtt     5100

ggcaaagtct tctttgaata tcagggactg agtcaataaa aaaaatagta gaaaggtggc     5160

ttttactatt gacaaaagcc ggggtcaaaa aaagtagttt aagtcttaag actgaatatg     5220

cattaaagta tgcaggtagc aaagatgtaa taaatttgct taaaaaaaga aattaaagtt     5280

ttatttagaa tcaattttac ctgtcattgt aattgaccca tctgagaatt acaataagca     5340

agaggaaatt aaggtgtttt gcaagagctg tatttatatt acagtttttt aaaaacattt     5400

tctgaattat cgtaattaag ctctccaact cgttaagtca gaatataata tgaagttccc     5460

caaggaaacg aacaaaatga actctagaat atctagcaaa tagttaaaga agcaatttat     5520

tattagggca tactcgggct gtttccaaat ataaactcta ttgcaatatc ttatttcatc     5580

tttctaatac atgtacagtg cacactagag gatagagctg catcacttaa attcatgact     5640

taaaaaataa tacagtttat atacaacttg ttttttattt gattaagaag tgaagtttac     5700

gccacccaat gtatagccaa attgtacgtg cttaaaaaac agtgccgaga gtatgttcag     5760

ttcgcagtaa gtagatttat tggaataaat attctatggt acattctcag aaattggctt     5820

ccaactaaaa tacgtttgac ccattttgaa taaggaaatt gaaaagaaaa atttaaaagg     5880

agaaaaaaat gcatgtttat aaacttttta aataaaacca gaccttgtaa gtggacatta     5940

ataattgtcc tgcctcattt gttttcacga ctttgacaac aagaagttcc tgaacattag     6000

tcatgtatgc tcagaataaa tgtgactttg aaatatatgt tagctactgt acatgtatag     6060

tcagtcaagt agaagaggac cttcctgaaa ttcccacttg tgacattttc ccatgggttt     6120

cctacacaat cttaaatttt atttctgtct atactttctc aaatttttcc tatgataagt     6180

tcagttgttg gtactcttct aaaaatattc aacgtgatta ggatcagttc taaaatacgg     6240

gacccctttg agtgacaatt cgcactccat gcattattgg ctcagtagcc aatttttgtc     6300

acgtcgttat aacaaggaga tgacataatt aaacatttcc atcctttcta ttccctgaga     6360

ctgcatcagc acaggcaagt atagaatgta atgttcttca tgggccccac cagctttttg     6420

gtgccatgta atttatttct tcgctgaaga gaaaaagaat tctgagacac agttattaaa     6480

ccctttatca actttctacc atcagtgcct gaattctaat gcagtgtgat ttctctggga     6540

caaagagact gaggaagatg aaaagtttct tcaaagagtg aatacatact tattcacaac     6600

tctaggatgt gaggacttta aatatctctt tatgaagttc cctgcctaac ctctttctat     6660

ttaaaggcaa acaaatttcg aagaggtttt gtgttccctc tttatgtttc tctatgaccc     6720

agtttagtct aaaaccttag ttcattacat atacaacaca tagcctttga tccctggtaa     6780

ctggcaggtg ttggtgatta ataaaccaag gcttcaaagt gaagtatgtg tgtgcagatg     6840

acttttggaa taacgtgggc atagcatcat accttcctga ttgtcttcag catataaaaa     6900

ttaactgttg tagttaaaat tatgtcagtg cagagcttgt ggttacttgg aatgttcttt     6960

cagaatagtc catgttgcct attaaaccta gttttaaaca cattgggcag tcaatttatg     7020

cacccaaaat atcaccctca ggtagattga gggcaagata aaatgctgta tgtagctata     7080

caaaggaatt cagaaacatt actggaaagc aaagcctttg tcagcttgct actgacaaag     7140

tagtaaaaag ctactaatca gtgttgagtc agatgtcaac agaaaaatac aaatacctat     7200

gagagccaca gcagtttctc gtttcatagc cgattcaatg aatatgatta gaaattcact     7260

gagctcactc ttgcaggttt aaatggaggc ctgcataagg actgcaagag gaaatctggg     7320

tgggagagaa tgtaatctga tcttgcactc ataggcaatg ctgcaatgca atcatgtcca     7380

atacaagcac agcttcattc ataacaggaa acgtcttctt tgggaaaata gctctattgg     7440

tgcccaaact caggtatgcc agtgtatgca ggtggagtcg ccctacccct cttccaaaca     7500

tgtcctgtga gatttttaaa ataagatggg atagtacagg ggcatgaaaa gaattgattc     7560

cttcacagga tttgaatcca gttcaaggga gaatgtagaa aattcaaaac caacatataa     7620

ggtatcacac aaccaagaaa agtaaaacca ttgcaagttt acttgcgttg agtacaaaac     7680

agatttaatg gtgttctatg tcatagttta atgctctggg tatttaaata tgttttcaac     7740

aggatttgag ttgaaagttt gtaatgtgct ttgatggaac acctctcaat ttctattcaa     7800

taaacttatg taattgtcca ttgacaatat aatgataaca gtaccattga actctaaact     7860

gtggtttatc ttcactactg ggaagcaact gtgcatcagt attaaagata tgcagaaaca     7920

taatattcac taatttgttc atctgcttct gtatattgtt tatggaatta catggcaaga     7980

actgttctaa agcaacatgt ctttccacat tattttagag gtgaaattac ttttgttttg     8040

cttctctata atgtgtactt caaatgaaac accatacttt tttctaaaaa aagatgttca     8100

atttactaat ttttttaaat ctcataattt aaaaagcatt tgttgtgatt ttaaagtgtt     8160

gcaagaaaag ggattttgtg gccgtgggta gactttttat actttgtttt atagatggat     8220

tttttttaac tgtagtttgt ttaagtcacc aagcagcatc caaaatctta atgtgtttca     8280

tttgatgttg ttagatcaga gaagaaattg gcataaaatc ggttaatagt attgtcaaag     8340

aattgtgtat tgtgtactca ctgggaaaaa ataaaatata ttcacatttc aaa            8393


<210>  584
<211>  4006
<212>  DNA
<213>  homo sapiens

<400>  584
gaggaggagg ggacccgccg ccgggggctg gctgcttcgc tccgagccga cttttcgcca       60

atggtccaaa gggacatgtc caagtcgcct cccacagcgg cggcggcggt ggcgcaggag      120

atccagatgg aactgctaga gaacgtggct cccgcggggg cgctcggagc cgccgcacag      180

tcatatggaa aaggagccag aaggaaaaac agatttaaag gatctgatgg aagcacgtca      240

tctgatacta cctcaaatag ttttgttcgc cagggttcgg cagactccta cactagccgt      300

ccatccgatt ccgatgtatc tctggaggag gaccgggagg cagtgcgcag agaagcggag      360

cggcaggccc aggcacagtt ggaaaaagca aagacaaagc ccgttgcatt tgcggttcgg      420

acaaatgtca gctacagtgc ggcccatgaa gatgatgttc cagtgcctgg catggccatc      480

tcattcgaag caaaagattt tctgcatgtt aaggaaaaat ttaacaatga ctggtggata      540

gggcgattgg taaaagaagg ctgtgaaatc ggattcattc caagcccagt caaactagaa      600

aacatgaggc tgcagcatga acagagagcc aagcaaggga aattctactc cagtaaatca      660

ggaggaaatt catcatccag tttgggtgac atagtaccta gttccagaaa atcaacacct      720

ccatcatctg gtgcaaaatc tgcagatgaa caagaccagt ggaaaactgc aggcttgttt      780

tggcggttta ctacagagca cactcctccg tatgatgtgg taccttccat gcgaccagtg      840

gtcctagtgg gcccttctct gaagggctac gaggtcacag atatgatgca aaaagcgctg      900

tttgattttt taaaacacag atttgaaggg cggatatcca tcacaagggt caccgctgac      960

atctcgcttg ccaaacgctc ggtattaaac aatcccagta agcacgcaat aatagaaaga     1020

tccaacacaa ggtcaagctt agcggaagtt cagagtgaaa tcgaaaggat ttttgaactt     1080

gcaagaacat tgcagttggt ggtccttgac gcggatacaa ttaatcatcc agctcaactc     1140

agtaaaacct ccttggcccc tattatagta tatgtaaaga tttcttctcc taaggtttta     1200

caaaggttaa taaaatctcg agggaaatct caagctaaac acctcaacgt ccagatggta     1260

gcagctgata aactggctca gtgtcctcca gagctgttcg atgtgatctt ggatgagaac     1320

cagcttgagg atgcctgtga gcaccttgcc gactatctgg aggcctactg gaaggccacc     1380

catcctccca gcagtagcct ccccaaccct ctccttagcc gtacattagc cacttcaagt     1440

ctgcctctta gccccaccct agcctctaat tcacagggtt ctcaaggtga tcagaggact     1500

gatcgctccg ctcctatccg ttctgcttcc caagctgaag aagaacctag tgtggaacca     1560

gtcaagaaat cccagcaccg ctcttcctcc tcagccccac accacaacca tcgcagtggg     1620

acaagtcgcg gcctctccag gcaagagaca tttgactcgg aaacccagga gagtcgagac     1680

tctgcctacg tagagccaaa ggaagattat tcccatgacc acgtggacca ctatgcctca     1740

caccgtgacc acaaccacag agacgagacc cacgggagca gtgaccacag acacagggag     1800

tcccggcacc gttcccggga cgtggatcga gagcaggacc acaacgagtg caacaagcag     1860

cgcagccgtc ataaatccaa ggatcgctac tgtgaaaagg atggagaagt gatatcaaaa     1920

aaacggaatg aggctgggga gtggaacagg gatgtttaca tccgccaatg agttttgccc     1980

gtttgtgttt tttttttttt ttttttgaag tcttgtataa ctaacagcat ccccaaaaca     2040

aagtctttgg ggtctacact gcaatcatat gtgatctgtc ttgtaatatt ttgtattatt     2100

gctgttgctt gaatagcaat agcatggata gagtattgag atactttttc ttttgtaagt     2160

gctacataaa ttggcctggt atggctgcag tcctccggtt gcatactgga ctcttcaaaa     2220

actgttttgg gtagctgcca cttgaacaaa atctgttgcc acccaggtga tgttagtgtt     2280

ttaagaaatg tagttgatgt atccaacaag ccagaatcag cacagataaa aagtggaatt     2340

tcttgtttct ccagattttt aatacgttaa tacgcaggca tctgatttgc atattcattc     2400

atggaccact gtttcttgct tgtacctctg gctgactaaa tttggggaca gattcagtct     2460

tgccttacac aaaggggatc ataaagttag aatctatttt ctatgtacta gtactgtgta     2520

ctgtatagac agtttgtaaa tgttatttct gcaaacaaac accttcttat tatatatata     2580

atatatatat atatcagttt gatcacacta ttttagagtc ttaatgccaa gtcagcagat     2640

ttgctttatg aattacaggg actagaaatg cccacattca ggaaatttgt aataacattg     2700

tctagacacc tatcctcatt ctagtagaaa gtgtgtacat actgtaaata tgtgtgattg     2760

cttgacttga aaaggtttga attctgaatg ttataccatc cttgtaagta agtttgtaat     2820

ttccaccata aattatggta aatataaaac tccagaggtt gttctactcc atacagttca     2880

cactgattgt gacacattct tagtagctag tgtctgttct agtcactgca ctggagtcta     2940

cgagccggaa ctcgctatat gcacgtgtgt gtgtccgtat gtaagaaagt gtgcaccgag     3000

tgactgaatg gttgagatga attggaatgc tgaagactaa cgaagaaact agagactgat     3060

atcgagcatt ctgcccacct cgctctgtat ttaattaatt gtgctatatg ttgctttaac     3120

aacccattga gcagtcaggg aatgtgagta agcttgctgc caaaggtaac taggaaagca     3180

ttcatctgct gcctccttgt ttttgctcct agagagtgaa aatacaggca attttactgt     3240

gagtgtttca ctggaaatgt acaatctttg tgtgttagag tatttgtttt agtaagaaat     3300

gtttacacag cttgtggaat tatttcgtgg gaaaataaat ttttataact tctcccactt     3360

caatttctaa ccttgcctat tgttcctgtt gtttgtttac ctcccagtta cctaccattc     3420

ctccccacca ccgactccag caggttcact gtctgtcaga acccagaagt gcttcttata     3480

accaaagttt ctgttcttca gaagaaatca gggcaaaatg gggtgacttg aagtgaataa     3540

aatgttaaga atattatcct acataagaca tgtacacaga aggggaacct tgaagacatt     3600

atctccatgc ctcaattaca ctgctgtaag aagcttacaa tgtcatcatg tttaaggcta     3660

agaccttttc cgtgtctcaa gtgtatattt tgtccagtta taactggatg gtaagacagt     3720

attaagagtg caagtacctg gcacttgaag tttgtcccag gaaaatgcct gtgtataatt     3780

acctaacttc agatctgcac attaacttat ttaacaaaat aaatcagccg ggcgcagtgg     3840

ctcatgcctg taatcccagc aatttgggag gctgaggagg gtggatcacc tgaggtcagg     3900

agttcaagac cagcctggcc aacgtggcga aaccccgtct ctactaaaaa gataaaaaat     3960

tagccaggtg tggtggtgca cacctgtaat cccagctact tgggag                    4006


<210>  585
<211>  10351
<212>  DNA
<213>  homo sapiens

<400>  585
gcacgggctg gtctctgccc taatgcggcg gctggcggcg agaggcgctg caggggacgc       60

gggggaagtg gcggcgccgg cagcggacag ctcggacagc gcccagggcc ggagcccgag      120

cccttggagg ttgattgact tatgtgcaat ttgggacgct ggagtttacc ttccctccgc      180

agcctggaac agagcctcct ctggtgttgc aaggaagagg ctgaatgagg cagagaagct      240

gagtgctgtc caggaggccc agttaaagcg gctcgaggtg acaagacccc gagtgctggg      300

gagcagggag cagggccagg tgccgaggat ggccaggcag ccaccgccgc cctgggtcca      360

tgcagccttc ctcctctgcc tcctcagtct tggcggagcc atcgaaattc ctatggatcc      420

aagcattcag aatgagctga cgcagccgcc aaccatcacc aagcagtcag cgaaggatca      480

catcgtggac ccccgtgata acatcctgat tgagtgtgaa gcaaaaggga accctgcccc      540

cagcttccac tggacacgaa acagcagatt cttcaacatc gccaaggacc cccgggtgtc      600

catgaggagg aggtctggga ccctggtgat tgacttccgc agtggcgggc ggccggagga      660

atatgagggg gaatatcagt gcttcgcccg caacaaattt ggcacggccc tgtccaatag      720

gatccgcctg caggtgtcta aatctcctct gtggcccaag gaaaacctag accctgtcgt      780

ggtccaagag ggcgctcctt tgacgctcca gtgcaacccc ccgcctggac ttccatcccc      840

ggtcatcttc tggatgagca gctccatgga gcccatcacc caagacaaac gtgtctctca      900

gggccataac ggagacctat acttctccaa cgtgatgctg caggacatgc agaccgacta      960

cagttgtaac gcccgcttcc acttcaccca caccatccag cagaagaacc ctttcaccct     1020

caaggtcctc accacccgag gagttgcaga aagaacacca agcttcatgt atccccaggg     1080

caccgcgagc agccagatgg tgcttcgtgg catggacctc ctgctggaat gcatcgcctc     1140

cggggtccca acaccagaca tcgcatggta caagaaaggt ggggacctcc catctgataa     1200

ggccaagttt gagaacttta ataaggccct gcgtatcaca aatgtctctg aggaagactc     1260

cggggagtat ttctgcctgg cctccaacaa gatgggcagc atccggcaca cgatctcggt     1320

gagagtaaag gctgctccct actggctgga cgaacccaag aaccttattc tggctcctgg     1380

cgaggatggg agactggtgt gtcgagccaa tggaaacccc aaacccactg tccagtggat     1440

ggtgaatggg gaacctttgc aatcggcacc acctaaccca aaccgtgagg tggccggaga     1500

caccatcatc ttccgggaca cccagatcag cagcagggct gtgtaccagt gcaacacctc     1560

caacgagcat ggctacctgc tggccaacgc ctttgtcagt gtgctggatg tgccgcctcg     1620

gatgctgtcg ccccggaacc agctcattcg agtgattctt tacaaccgga cgcggctgga     1680

ctgccctttc tttgggtctc ccatccccac actgcgatgg tttaagaatg ggcaaggaag     1740

caacctggat ggtggcaact accatgttta tgagaacggc agtctggaaa ttaagatgat     1800

ccgcaaagag gaccagggca tctacacctg tgtcgccacc aacatcctgg gcaaagctga     1860

aaaccaagtc cgcctggagg tcaaagaccc caccaggatc taccggatgc ccgaggacca     1920

ggtggccaga aggggcacca cggtgcagct ggagtgtcgg gtgaagcacg acccctccct     1980

gaaactcacc gtctcctggc tgaaggatga cgagccgctc tatattggaa acaggatgaa     2040

gaaggaagac gactccctga ccatctttgg ggtggcagag cgggaccagg gcagttacac     2100

gtgtgtcgcc agcaccgagc tagaccaaga cctggccaag gcctacctca ccgtgctagc     2160

tgatcaggcc actccaacta accgtttggc tgccctgccc aaaggacggc cagaccggcc     2220

ccgggacctg gagctgaccg acctggccga gaggagcgtg cggctgacct ggatccccgg     2280

ggatgctaac aacagcccca tcacagacta cgtcgtccag tttgaagaag accagttcca     2340

acctggggtc tggcatgacc attccaagta ccccggcagc gttaactcag ccgtcctccg     2400

gctgtccccg tatgtcaact accagttccg tgtcattgcc atcaacgagg ttgggagcag     2460

ccaccccagc ctcccatccg agcgctaccg aaccagtgga gcaccccccg agtccaatcc     2520

tggtgacgtg aagggagagg ggaccagaaa gaacaacatg gagatcacgt ggacgcccat     2580

gaatgccacc tcggcctttg gccccaacct gcgctacatt gtcaagtgga ggcggagaga     2640

gactcgagag gcctggaaca acgtcacagt gtggggctct cgctacgtgg tggggcagac     2700

cccagtctac gtgccctatg agatccgagt ccaggctgaa aatgacttcg ggaagggccc     2760

tgagccagag tccgtcatcg gttactccgg agaagattta cccagtgccc ctaggcgttt     2820

ccgagtccgg cagcccaacc tggagacaat caacctggaa tgggatcatc ctgagcatcc     2880

aaatgggatc atgattggat acactctcaa atatgtggcc tttaacggga ccaaagtagg     2940

aaagcagata gtggaaaact tctctcccaa tcagaccaag ttcacggtgc aaagaacgga     3000

ccccgtgtca cgctaccgct ttaccctcag cgccaggacg caggtgggct ctggggaagc     3060

cgtcacagag gagtcaccag cacccccgaa tgaagctact ccaaccgcag ctcctcccac     3120

attgcccccg actaccgtgg gtgcgacggg cgctgtgagc agtaccgatg ctactgccat     3180

tgctgccacc accgaagcca caacagtccc catcatccca actgtcgcac ctaccaccat     3240

cgccaccacc accaccgtcg ccacaactac tacaaccact gctgccgcca ccaccaccac     3300

ggagagtcct cccaccacca cctccgggac taagatacac gaatccgccc ctgatgagca     3360

gtccatatgg aacgtcacgg tgctccccaa cagtaaatgg gccaacatca cctggaagca     3420

caatttcggg cccggaactg actttgtggt tgagtacatc gacagcaacc atacgaaaaa     3480

aactgtccca gttaaggccc aggctcagcc tatacagctg acagacctct atcccgggat     3540

gacatacacg ttgcgggttt attcccggga caacgagggc atcagcagta ccgtcatcac     3600

ctttatgacc agtacagctt acaccaacaa ccaagcggac atcgccaccc agggctggtt     3660

cattgggctt atgtgcgcca tcgccctcct ggtgctgatc ctgctcatcg tctgtttcat     3720

caagaggagt cgcggcggca agtacccagt acgagaaaag aaggatgttc cccttggccc     3780

tgaagacccc aaggaagagg atggctcatt tgactatagt gatgaggaca acaagcccct     3840

gcagggcagt cagacatctc tggacggcac catcaagcag caggagagtg acgacagcct     3900

ggtggactat ggcgagggtg gcgagggtca gttcaatgaa gacggctcct tcatcggcca     3960

gtacacggtc aaaaaggaca aggaggaaac agagggcaac gaaagctcag aggccacgtc     4020

acctgtcaat gctatctact ctctggccta acggagccca cccaggcaca gccaccactt     4080

tgcaagtggg aggaggggag aaggggagac aaaaccactg cagacctacc acgaagccac     4140

caccaccttc agtaacaagg gtacgatatg ggggtctgcc aagctgtgag gaccagtagc     4200

caccaagcca cccacaagcc ccctcccaat gacccccctt cagccccggg tgccaccagt     4260

gtgggagagc tggagccgtg gctgagctca gctggaggga gcctggcccc ttgcccggtc     4320

tcgcagccac cccgagcgtt ccaccacact gtccgccctt ggcctcggca cacgctcacc     4380

ttttctgttg gttacgggac ttctcattgt cttaatttcg ctttgtgcat cttcccctcc     4440

agacccaatg tctctgtttt cttttccttt tgaaaaagag tccctggaaa agaaagaata     4500

agtggattct cccccaggag aatccttttt gcaaagatag gcaaaaagga ttgaatccat     4560

accagaacac gtagacaggc tgtaatattc aaaccacctc tgggccaatg catttccaaa     4620

ggatgccttt ctcgccatat gcctcccctg gcccccagcc cctctgcctc ggccttgtca     4680

gttgctgagc tgggcttggc tcctttctgg aaaatgacag tatttttggc agggagaagg     4740

tgcgcaggcc tccttgctgc tctctggttt ggttgggagg tgtgtttacc tcttgctcct     4800

cattcctccc ctgccctttt ctctggaata tctaagatgt gagctgcatt gactctgaag     4860

acgtttgagg aacaggagtg ggcactgata gaaaggactt caacgccagt gactgtgtac     4920

ctccagcaga agaaaatcag gtgtctggtc ttgggggcac tgtgctcact tctagagaga     4980

agaaaaaggc tgggtttgga cttcatgcct cctcactggt gaaacccagg atgtagatag     5040

agggccacac ccaccctgtc cagagtagag ggcacctgtc cacgtggcca gggcccatgc     5100

tgccaccctc gaggagatgg aaccctgtga tgcaaaagct ttgctggtgt gtttggggca     5160

taaggcactg ctccccttcc atctctagca gatatcatct tctcagccaa ttctgtagga     5220

cactgaggct cttgtttgac atggtgtgtg gatggggact tgccccaaga ctgagcaggt     5280

ctgccctttc attggggtgt atacatatca ggggaccctg aggtggcacc gtactcagtg     5340

ttgtgatgcc cccacctagg gaggactcaa tgctctttgt atgccttatg cagcgctgat     5400

ctgtccctgg agttcccagg ttcccagctc cccccctgca agccttgaag cctccagcaa     5460

cgtctatctc caggagagca gggcagccta tgcaagtgtt ccggcaggac cagaagtggc     5520

cactcaacac acgtcctcac cagtcacccc aaatggagac actcgcagac ctgcagttct     5580

cagaccgaag gtgctgcctt catcctcccc acctaatgca tttttgaaac caaaggtacc     5640

tagcctcaga gacagagaag gagaggggga gatcttgagt ctaagaggaa ccctttagct     5700

gtttctgcag ctgaggtcag tttcaggagg gtgaagctga tccccaggaa tggatcagct     5760

gccatgggca cagcctccga tttgagcctc tccggctgcc agccaggggg cctgggccag     5820

accagggctc tgtccttccg tgactttatt aaagcaacat ttgccacatg tttaagccgc     5880

aaaggtatta gcaatgcttg catcattaat aatcattcag ttgaaggtca agcccataga     5940

cacacactct ctgctggtaa gaaaccatag cccagaactg agccaataag gttgtttgaa     6000

cctgagagtg tgtaatggtc atttgggcca agcctcagct agggctgctg cctggacgcc     6060

tgaggggcag cttatcacag tgcaagggga cagggtaaac agcagggggt ggggtgtgag     6120

cttggagggc ccctcccctg gatttcctcc aacacctgct tggatactag gcccactgtc     6180

cctgaaggga atgtcaggga agtgtgcctg tgagctgaat taaaggactg gcctttccag     6240

aaaacgcttt ggatctgagc agagtagtca gtttctcaga cactcattcc atactgcacc     6300

gtacatgcca gcgtacccat tgcaccgaaa gcaggccctt agggcaggaa gggacgatga     6360

gcaagtctgc cacaccacct ggtgactggg aagggctgct tctctcgtaa gggtcttggg     6420

gagaagtaag cccgcagcct gcctctgcac ctcgttccag tgtcctgcca ggctctgtac     6480

tgtcctttgt gtatgaagaa aatgctgtta gccctctctc aggctgctgt tctgtgggtg     6540

ctgagagctg ccccccatca ccacgccatc acacccctct gagcagaagc aaatctgagg     6600

ctgaagaatt aagttttccc caagcaagga aggcaggtgg tcagagagat caaacgctga     6660

ggcgtgggga ttgcaggatt caggaggcag cccctttggg gaagaggagg gtgcattttc     6720

catggagccc atgtcagagt ccactccagc tcagcaggaa agtggaattg cccagtactg     6780

cctgccagct gggtctccca agcaactacc ccaagacata ccaacagtga agccaggaca     6840

gcaccatgcc atcggcgctc cagtctgtct ggctgggagg aaagtgctgg gcatcttaca     6900

gtaactctag aagttccttt gactaggctg caatcccacc tatatgctca gccctaagag     6960

ctgtggtttc ctgtgctctc atttgtccat tcattcattc attcattcat tcagcaaata     7020

atctgaaatc cagtctgaac taaggcctga gctgtggata ccatggcgcg tgagttagat     7080

gtggtccctg ccctcatggg gctgacagtc ctaaaatcaa gtgctaggac acagtggcca     7140

ttgagctggg agcattcttc cctctaccgc ttaagccact gatggctgcg agcttgaaga     7200

gagggattct gagggagagc ttggtccatc tggtcaccaa ggctgggcgg gacagagcag     7260

tcaagaacca cggtgtggct tgagaaacag tcctgcttcc tgagcctctt tgctctgcct     7320

cttggggcaa gctccttaac ctgtctgtat ttttatgcct ctgtctccca ttcagttcct     7380

ccttgaatac ctctttctac agagaggcac gggctcccct gaaggattgt cgaggccagg     7440

gttcgggaag tacactgcca tcggtcaggg gacagctgcc tcccaccttg cctgggtgat     7500

ggtgaatggg actcatcttt tcctgccttg cttttgagga gatggttgaa tttaagctaa     7560

caggaaagcc aaaccagcac cctcctttgt gctctgagag gttggagaca tctggtccac     7620

cccattgccc ctgcccctgg caagccctga agtcgggaga ggtgaccaca ggtctgaaaa     7680

tcagccagtg ccaacattgc ttgccctgca aggtgcaact gagcccacat agcgcattca     7740

tagtttccct gaccacagcc ttgggaagac ggtggaaacc cgaggatgtg tgggtttccc     7800

agctaacgga caagctcccc tgccacaccc agtgcccacg catgctcaca tacatacagc     7860

agaccacaac cctgttgcca agcagtgctt ccaagggata gcgatccaga ttccaacatt     7920

gtcttggaga gggttagtcc acatccaagt tgcgtgagat aagatgcaaa gggctctgtg     7980

tggatgagga acgcacctta gaggagtggg aaaggccacc agggttgggc cctgtttagg     8040

taattcctgt tggcagcacc tagagagagc atctgagctg aaggagtggg aaactttgcc     8100

caagcaatgg cacgggcagc gggctctttc tggcgccctg tgctggagca gggccaagtc     8160

ttagggcatc acaaacagcc catttgatgg agggagcagg gacatagcac atttttgtct     8220

gtctttgtga ggctgctttg ctaactctct gaggagagga agcctctcgg gctttccgtc     8280

ggctggggct agtgccagag aatcccttct cagtggccag caggttcctg ggaggccggc     8340

acaaggcacc gctccccact catgacacct tggtgcagag tgacctcctg cccagtcacc     8400

actccggcca gccccagcca aacacacaaa agcccatggt tgcggttgca tctacaccgt     8460

tagttggcaa aggatcctgc ttgagctctg cgtggtggcc aaggagtagc atggaggagg     8520

gccctgattt taaaaaggaa aaatagagag gcctcaaaac aatgaaacaa agagcttgat     8580

atgtcaagag gagaccaagg ccctgggagg cataggcaag ccgggcagag tcagaccagt     8640

gccctccctt gaccatctcc tagcattcct taacctagac aggggctacc ccatgtgagt     8700

ccaagccaga ctttgtggct gtccccagcc tgcacagccc aagcccaggg aagtgtcctt     8760

tctttccctt ccttactaat aatgggcctt cctgagacac attcagagaa ggatcagaga     8820

gaaaggagaa ccatccagga gagccacaag cgtccaccaa acagtgtctc aggcctcacc     8880

tgaagctgct gttcctccta tcagcacact agtattaaat gggtgttcca taatgaggag     8940

aatggaaata ggtacaaggc atctagctta ggacagaatc ggatttcggc atgtgaagga     9000

atcccagagc tgatctcatt gaaatgatct atcgtacaga caaggatatg caaatccaca     9060

gaagtgaagg gatttttgct caagatcaca tagctggtaa actaaggtaa ggttagggct     9120

tgaacttggg ccttctgact ccttgtccag tcagtgttct ttcatctcac cacagctgcc     9180

tcctttgaaa cagaggtatt aagatctgtc cttctggttc accctctcat acctctttac     9240

tgcgtctccc acatccccca catgcctccc aaaatgaaag acaaacagga ttgtttctga     9300

gaccaagatc agtctgtctg tgatcagcct gtgtgtggtt cacccagtca tgcaattaag     9360

ggcagatctg ggccagtgga ataggatagc tgattggtgt ttgttactgt gaaccctaga     9420

ccgtaccccg tagaatggtg tctcttgctt tgtaacacat cgggccttca gtgtgctgta     9480

ttcctcagaa gtgagggcat ctcggtccat tctgcccatg gccacagggt gcagagaggc     9540

agcagggccc atgcaagctg ccaccctggg atttgctggg ctggagttca acagatgtaa     9600

agacttcagt gaagcaataa acacaaaact ctgggagaag atatccagaa ttttgtacat     9660

tactctgttt ctttttcaaa aatgaggcag atcagatgcc cctgagctgc cccttttttt     9720

ctgattccca actgcaatgt cctcagtcag tgttgtccct ctgcccggct ccccagctct     9780

ttgccaacct cttcacactc cccttgagct gagcatcagt cgcctgtgac gtggccacct     9840

tctgtcctgc tcccactccc gacccatgct ggaccccgga ggacctcctg ccccgccccc     9900

accacacacc catatccccc accattccaa tttgttcttt cccgtgggga attttttttc     9960

ccagcgtctc catcccttcc tacatatcca cacacacaca aattggtctg atcttttttc    10020

cattggttaa acatttaact ccatgccaga ccttgtttta acccctctca catcatgttc    10080

tttccttttt tgcgagttat tttgcattaa ccaactttgt cagtgacaga tgcgtatctg    10140

agggtgtcac acacgacctt cagcagggaa gacttctggg ccatggaggg ccgtctaata    10200

catggactta taaactgact gcatgagcaa tgaaaaggcc aaattattct gaattttttt    10260

tgaatcactg taaaaaaact gatttctttt gtatagagaa cactaaacgt ataataaaag    10320

ttgttcaaaa tggaaaaaaa aaaaaaaaaa a                                   10351


<210>  586
<211>  2070
<212>  DNA
<213>  homo sapiens

<400>  586
gccaattgct gaccgccaca gccacagcca gggctagcct cgccggttcc cgggtggcgc       60

gcgttcgctg cctcctcagc tccaggatga tcggccagaa gacgctctac tcctttttct      120

cccccagccc cgccaggaag cgacacgccc ccagccccga gccggccgtc caggggaccg      180

gcgtggctgg ggtgcctgag gaaagcggag atgcggcggc catcccagcc aagaaggccc      240

cggctgggca ggaggagcct gggacgccgc cctcctcgcc gctgagtgcc gagcagttgg      300

accggatcca gaggaacaag gccgcggccc tgctcagact cgcggcccgc aacgtgcccg      360

tgggctttgg agagagctgg aagaagcacc tcagcgggga gttcgggaaa ccgtatttta      420

tcaagctaat gggatttgtt gcagaagaaa gaaagcatta cactgtttat ccacccccac      480

accaagtctt cacctggacc cagatgtgtg acataaaaga tgtgaaggtt gtcatcctgg      540

gacaggatcc atatcatgga cctaatcaag ctcacgggct ctgctttagt gttcaaaggc      600

ctgttccgcc tccgcccagt ttggagaaca tttataaaga gttgtctaca gacatagagg      660

attttgttca tcctggccat ggagatttat ctgggtgggc caagcaaggt gttctccttc      720

tcaacgctgt cctcacggtt cgtgcccatc aagccaactc tcataaggag cgaggctggg      780

agcagttcac tgatgcagtt gtgtcctggc taaatcagaa ctcgaatggc cttgttttct      840

tgctctgggg ctcttatgct cagaagaagg gcagtgccat tgataggaag cggcaccatg      900

tactacagac ggctcatccc tcccctttgt cagtgtatag agggttcttt ggatgtagac      960

acttttcaaa gaccaatgag ctgctgcaga agtctggcaa gaagcccatt gactggaagg     1020

agctgtgatc atcagctgag gggtggcctt tgagaagctg ctgttaacgt atttgccagt     1080

tacgaagttc cactgaaaat tttcctatta attcttaagt actctgcata agggggaaaa     1140

gcttccagaa agcagccatg aaccaggctg tccaggaatg gcagctgtat ccaaccacaa     1200

acaacaaagg ctaccctttg accaaatgtc tttctctgca acatggcttc ggcctaaaat     1260

atgcagaaga cagatgaggt caaatactca gttggctctc tttatctccc ttgcctttat     1320

ggtgaaacag gggagatgtg cacctttcag gcacagccct agtttggcgc ctgctgctcc     1380

ttggttttgc ctggttagac tttcagtgac agatgttggg gtgtttttgc ttagaaaggt     1440

ccccttgtct cagccttgca gggcaggcat gccagtctct gccagttcca ctgccccctt     1500

gatctttgaa ggagtcctca ggcccctcgc agcataagga tgttttgcaa ctttccagaa     1560

tctggcccag aaattagggc tcaatttcct gattgtagta gaggttaaga ttgctgtgag     1620

ctttatcaga taagagaccg agagaagtaa gctgggtctt gttattcctt gggtgttggt     1680

ggaataagca gtggaatttg aacaaggaag aggagaaaag ggaattttgt ctttatgggg     1740

tggggtgatt ttctcctagg gttatgtcca gttggggttt ttaaggcagc acagactgcc     1800

aagtactgtt ttttttaacc gactgaaatc actttgggat attttttcct gcaacactgg     1860

aaagttttag ttttttaaga agtactcatg cagatatata tatatatatt tttcccagtc     1920

ctttttttaa gagacggtct ttattgggtc tgcacctcca tccttgatct tgttagcaat     1980

gctgtttttg ctgttagtcg ggttagagtt ggctctacgc gaggtttgtt aataaaagtt     2040

tgttaaaagt ttaaaaaaaa aaaaaaaaaa                                      2070


<210>  587
<211>  2642
<212>  DNA
<213>  homo sapiens

<400>  587
gtttctctcc ctgcccccgc gacttcgcgc aagatccggg aaggacaccc gaggcccctg       60

ggagaccctg gggaggtgaa aatcagagag cgaagcgggc cgtggcccct aggcctgacc      120

cctccccgcg gggtaaggcg ggcaccccgc gagcgcaggg gtcctcttac tgctgatggc      180

acccagctct gggcccagac gccgctcacc gtccaccgcc ggtgctgggt aaaatgtcgg      240

ttccaggacc ttaccaggcg gccactgggc cttcctcagc accatccgca cctccatcct      300

atgaagagac agtggctgtt aacagttatt accccacacc tccagctccc atgcctgggc      360

caactacggg gcttgtgacg gggcctgatg ggaagggcat gaatcctcct tcgtattata      420

cccagccagc gcccatcccc aataacaatc caattaccgt gcagacggtc tacgtgcagc      480

accccatcac ctttttggac cgccctatcc aaatgtgttg tccttcctgc aacaagatga      540

tcgtgagtca gctgtcctat aacgccggtg ctctgacctg gctgtcctgc gggagcctgt      600

gcctgctggg gtgcatagcg ggctgctgct tcatcccctt ctgcgtggat gccctgcagg      660

acgtggacca ttactgtccc aactgcagag ctctcctggg cacctacaag cgtttgtagg      720

actcagccag acgtggaggg agccgggtgc cgcaggaagt cctttccacc tctcatccag      780

cttcacgcct ggtggaggtt ctgccctggt ggtctcacct ctccaggggg cccaccttca      840

tgtcttcttt tggggggaat acgtcgcaaa actaacaaat ctccaaaccc cagaaattgc      900

tgcttggagt cgtgcatagg acttgcaaag acattcccct tgagtgtcag ttccacggtt      960

tcctgcctcc ctgagaccct gagtcctgcc atctaactgt gatcattgcc ctatccgaat     1020

atcttcctgt gatctgccat cagtggctct tttttcctgc ttccatgggc ctttctggtg     1080

gcagtctcaa actgagaagc cacagttgcc ttatttttga ggctgttctg cccagagctc     1140

ggctgaacca gcctttagtg cctaccatta tcttatccgt ctcttcccgt ccctgatgac     1200

aaagatcttg ccttacagac tttacaggct tggctttgag attctgtaac tgcagacttc     1260

attagcacac agattcactt taatttctta attttttttt taaatacaag gagggggcta     1320

ttaacaccca gtacagacat atccacaagg tcgtaaatgc atgctagaaa aatagggctg     1380

gatcttatca ctgccctgtc tccccttgtt tctctgtgcc agatcttcag tgcccctttc     1440

catacaggga tttttttctc atagagtaat tatatgaaca gtttttatga cctccttttg     1500

gtctgaaata cttttgaaca gaatttcttt tttttaaaaa aaaacagaga tggggtctta     1560

ctatgttgcc caggctggtg tcgaactcct gggctcaagc gatccttctg ccttggcctc     1620

ccgaagtgct gggattgcag gcataagcta ccatgctggg cctgaacata atttcaagag     1680

gaggatttat aaaaccattt tctgtaatca aatgattggt gtcattttcc catttgccaa     1740

tgtagtctca cttaaaaaaa aaaaaaagaa aaagaaatgg ataatttcat ctactgcctt     1800

tacttggggt taatgtgatt cttaaacacc ttcatcatgg aactctcaga gtggggtccg     1860

ttttggtttc ctggtggtgg gttttgaaag ataagggaaa gcacattttg agcatgtctg     1920

ggtaccatgg tgcggatgct tgggaaccag aactgtttca gaggaatcta aagtctgatt     1980

ttagttttca gagacacagc ttgttgtaaa acatgagaag acatgatttc taggactcaa     2040

gcagcaagcc aggattctag gttggctgct gtgtcatctt tgaagtcaag acaaagctgg     2100

gctcgacctt caagggtcct cgttttgata atacttcaga atagggaact catgtgaata     2160

ctactatgta gaaataaaac ctagaccttg agcgaacatc tgtatattgg ttgaaaacga     2220

tagtggtaac cattgatccc ccttcatttg atgtttggaa aattccagta attatcattt     2280

ttgcaacgaa tatggatacc acatagtact ttggtgttac ctgcttttga aaaataaagt     2340

ctttggttca cccggtgaac tatttatgag ttcttttggt gtgaagaaag ggctcatgtt     2400

gcatttccag ccattgctac aaagaacctt tatttgttca gtaacggtag aaaatccttc     2460

ccgattaaaa acttcagact tgctgaatat cctgcaatgt caagatgacc gatgttgagt     2520

tgggtggatt tgctaacgag tcagatttga acatgaggct attggaaccc aataggcgtc     2580

attgatggcg gcaagccata gctttcaagt tttaataaaa tgcacaaaag agaaaaaaaa     2640

aa                                                                    2642


<210>  588
<211>  1890
<212>  DNA
<213>  homo sapiens

<400>  588
gaagaagttg gttcttgtct cgaatacttt tcctcccgtg ccccgcccct tgaatcagag       60

gcggctgtct cgtgcggcta gagcagggcc agtagagttc ggggcagctg tcaaaaacga      120

gacggggagg cttttcttcc cgggggtgga ggagggaagg agggaggtgt ccttttttcc      180

atctgttgca gtttccgaac caaacgcacc ctcgccagcc ccgggaagaa aggcccaagg      240

gagaaacctg gggcgctcgg ctggtgcccc caccgccggg cgagggatgc gggcggtccg      300

tgcgcggcag gcggaaagga tcgtgtttct ggacccggcc accccccgcg tccgcaccgc      360

cgcccccgag ggacgagtga cagcggccgc cgcgctcggt ccagtcttcc cggctggaag      420

gagcgggcgc ctgggatcag agcgtcctgt ttagcaataa cggctggagc acgtcctaca      480

agttacggga gagtcggctg tgaaggagac gttcgcttat cccctgtgtc cccgctcctg      540

gcccctccag acccccgcct tgcctcgcgc tgggagggga gatccagaat gaaaggcaag      600

aaaggtattg ttgcagcatc tggcagtgag actgaggatg aggacagcat ggacattccc      660

ttggaccttt cttcatccgc tggctcaggc aagagaagga gaaggggcaa cctacccaag      720

gagtctgtgc agattcttcg ggattggctg tatgagcacc gttacaatgc ctatccttca      780

gagcaagaaa aagcgttgct gtcccagcaa acacacctgt ctacgctaca ggtctgtaac      840

tggttcatca acgcccgccg caggctcctc cctgacatgc tgagaaagga tggcaaagat      900

ccaaatcagt tcacaatttc ccgccgtggg gccaagattt ctgaaacgag ctctgtggag      960

tccgtgatgg gcatcaaaaa cttcatgcca gctctagagg agaccccatt tcattcctgt     1020

acagctgggc caaacccaac cctagggagg ccactgtctc ctaagccgtc atccccggga     1080

tcagttttgg ctcgtccatc agtgatctgc cataccactg tgactgcatt gaaagatgtc     1140

cctttctctc tctgccagtc ggtcggtgtg ggacaaaaca cagatataca gcagatagcg     1200

gccaaaaact tcacagacac ctctctcatg tacccagagg acacttgtaa atctggacca     1260

agtacgaata cacagagtgg tcttttcaac actcctcccc ctactccacc ggacctcaac     1320

caggacttca gtggatttca gcttctagtg gatgttgcac tcaaacgggc tgcagagatg     1380

gagcttcagg caaaacttac agcttaaccc attttcaagc aaaacagttc tcagaaatgt     1440

catgattgcc ggggtgaagg caagagatga attgcattat tttatatatt ttttattaat     1500

atttgcacat gggattgcta aaacagcttc ctgttactga gatgtcttca atggaataca     1560

gtcattccaa gaactataaa cttaaagcta ctgtagaaac aaagggtttt cttttttaaa     1620

tgtttcttgg tagattattc ataatgtgag atggttccca atatcatgtg attttttttt     1680

tcctcccctt cccttttttt gttatttttt cagactgtgc aatacttaga gaacctatag     1740

catcttctca ttcccatgtg gaacaggatg cccacatact gtctaattaa taaattttcc     1800

attttttttc aaacaagtat gaatctagtt ggttgatgcc ttttttttca tgacataata     1860

aagtattttc tttaaaaaaa aaaaaaaaaa                                      1890


<210>  589
<211>  2465
<212>  DNA
<213>  homo sapiens

<400>  589
ctgagctgag tgacaggaag acggttcaat gggcggcgcg gaggcggagc cgtgggggcg       60

ggctcccggt cccgctatcg gcggccggcg ggcaggcgac tcctgtcccg ggtggaggcg      120

gcggagccgg agccggggga gggggcagcg gctgtctcac ggaccacggc ggcgcccgca      180

gctcctcacc gaaacaagga gaccagtgct ggtccagtgg ctgtgatggg aaaagattat      240

tacaagattc ttgggatccc atcgggggcc aacgaggatg agatcaagaa agcctaccgg      300

aagatggcct tgaagtacca cccagacaag aataaagaac ccaacgctga ggagaagttt      360

aaggagattg cagaggccta tgatgtgcta agtgacccca agaaacgggg cctgtatgac      420

cagtatgggg aggaaggcct gaagaccggc ggtggcacat caggtggctc cagtggctcc      480

tttcactaca cctttcatgg ggacccccat gccacctttg cctccttctt tggtggctcc      540

aaccccttcg atatcttctt tgccagcagc cgctccactc ggcccttcag tggctttgac      600

ccagatgaca tggatgtgga tgaagatgag gacccatttg gcgctttcgg ccgttttggc      660

ttcaatgggc tgagtagggg tccaaggcga gccccagaac cactgtaccc tcggcgcaag      720

gtgcaggacc ccccagtggt gcacgagctg cgggtgtccc tggaggagat ctaccatggc      780

tccaccaagc gcatgaagat cacaaggcgt cgcctcaacc ctgatgggcg aactgtgcgc      840

accgaggaca agatcctgca catagtcatc aagcgtggct ggaaggaagg caccaagatc      900

accttcccca aagaaggcga cgccacacct gacaacatcc ctgctgacat cgtctttgtg      960

ctcaaagaca agccccatgc acacttccgc cgagatggca ccaacgtgct ctacagtgcc     1020

ctgatcagcc tcaaggaggc gctgtgtggc tgcactgtga acattcccac tatcgacggc     1080

cgagtgatcc ctttgccctg caatgatgtc atcaagccag gcaccgtgaa gagactccgt     1140

ggggagggcc ttcccttccc caaagtgcca actcagcgag gagacctcat tgttgagttc     1200

aaagttcgct tcccagacag attaacacca cagacaagac agatccttaa gcagcaccta     1260

ccctgttcct aggctctgcc ccagccagtc cagagcctac cacagcaata cccccaacac     1320

tcactccact caatgtgcac ccagcttgat gtccactgga cactggcaac tttttctaaa     1380

atgcaaaaaa aagccactgg ttttcaggaa aatgttcctg tccctgaccc cttttagagc     1440

tgggctgcct ggggggagtg ggagggaggt ggggagagct agcccaggcc aggggtcaat     1500

gttcatgtca ctagctttca atccagtttc cactgcagtg gctggagagt gacctgagtg     1560

ctacttgaag atatgtagag attccttatc catgcctgta catagcatgt cctcctcccc     1620

tcagctttgc taataccagt cccctccctt ccctttggct tcctgctgtt gggggtggaa     1680

aagactagaa aggacattgc tttctcagcc ccacccccag gtccacagtg tccaaggtaa     1740

tggcacacat attcatgcac aagaagcact cacctagagc tgtctgtgcc tctctgggag     1800

aaaggagaga ggataagaag ggaaagttca caacctgtga acagggactt gagcacgaga     1860

cacttttcat ctggagcagg ggggtgagct cctcagcagc ctccgtaaca gctgccctgc     1920

ctacacctgc agagctggag gttctgtcct ccctgctgct ctcaggagtg ttcaagggtg     1980

gagggcaggg aatggggcct gaggtattaa ggctaagagg tgggggacag ggcccatcta     2040

ccagccttca tcaggaaggg aaagggcttt ggggtcaggt ggcagctatt ccccaccaag     2100

agattcaggg tcacaggttt ttccccacac ctctgaactc agggcctagc cacccccaaa     2160

cttccaaatc ccacttttgt gatatgtgaa gctactcatt tcttaccctt ggaggctgtg     2220

tggggaattt ccagcccttt tatgcctgtg tgatcccacc ccacccccat agttgtataa     2280

aggtcatagt gaagaagctg ggggaagact gcttcagcca gatcctgggg tggggtcttt     2340

aggttttctc actttgacaa cccccgaatg tttttatagt agtttttttg tatttttttg     2400

taatgacagt attatgtaaa aaataaagta ttttaaaaat atggcaaaaa aaaaaaaaaa     2460

aaaaa                                                                 2465


<210>  590
<211>  1300
<212>  DNA
<213>  homo sapiens

<400>  590
aagccgcaga gagcgggctc tgtcccgccc gctccccagg tggacgtggt cttggcatcc       60

acgccaatga gaatgtgagg gcggggcctg aatagacgca ggaaatggcg acggccgcgg      120

gtctgtgagc agcgggggcg gggcctggtt gtggcccctc cttctcccgt ccccaagttc      180

cctgggtggg aacggggtct tggggtccct ggctgggtgg ccagaccccg aagccagcgc      240

tgggaagggc tgcggatgcc cgggtcagag gaaggggcag gtccaaggac acgcgggtct      300

ggtcctgggc aagaaccgcc ccctctccgg gcctgcttca gtcttccttt gcagaacaac      360

gggccaggcc ccttccctct gcccccgggt gcttgaagtc tagccccatc ctggtccaat      420

gcgctcttgg tagcctcctt tcccagctgc ccgcccgccg ccatgccgcc cttactgccc      480

ctgcgcctgt gccggctgtg gccccgcaac cctccctccc ggctcctcgg agcggccgcc      540

gggcagcggt ccagacccag tacttattat gaactgttgg gggtgcatcc tggtgccagc      600

actgaggaag ttaaacgagc tttcttctcc aagtccaaag agctgcaccc agaccgggac      660

cctgggaacc caagcctgca cagccgcttt gtggagctga gcgaggcata ccgtgtgctc      720

agccgtgagc agagccgccg cagctatgat gaccagctcc gctcaggtag tcccccaaag      780

tctccacgaa ccacagtcca tgacaagtct gcccaccaaa cacacagctc ctggacaccc      840

cccaacgcac agtactggtc ccagtttcac agcgtgaggc cacaggggcc ccagttgagg      900

cagcagcaac acaaacaaaa caaacaagtg ctggggtact gcctcctcct catgctggcg      960

ggcatgggcc tgcactacat tgccttcagg aaggtgaagc agatgcacct taacttcatg     1020

gatgaaaagg atcggatcat cacagccttc tacaacgaag cccgggcacg ggccagggcc     1080

aacagaggca tccttcagca ggagcgacaa cggctagggc agcggcagcc gccaccatcc     1140

gagccaaccc aaggccccga gatcgtgccc cggggcgccg gcccctgagg ggctcacctg     1200

gatggggcct gcagtgcgtt cccgctttgc ttccttccct ggacggcccg ctccccgaaa     1260

cgcgcgcaat aaagtgattc gcagaaaaaa aaaaaaaaaa                           1300


<210>  591
<211>  3586
<212>  DNA
<213>  homo sapiens

<400>  591
gagctcgccg tcgctccgtc atagagttcg ccccacccca tcccctcctt tctggactcg       60

gagctcagtt cacgcagtaa caaatgaagt gcgcgctgcg acacctccca gcccaccgaa      120

ctccgccgcc atttcctcgc ttggcctaac ggttcggcca atcccagcgc gcatcaagaa      180

ggactgaggc tccgccaatc ggaggccgcc gatttcgacc cttcgcctcg gcccggccca      240

atccaggccc cggccccgcc gcccccggcc cgcccccgcg gtgccctctc tcctccctct      300

ttgtgcgtct cgcgccgccg ccgcccgccg cgtgagagga cgggctccgc gcgctccggc      360

agcgcattcg ggtcccctcc ccccgggagg cttgcgaagg agaagccgcc gcagaggaaa      420

agcaggtgcc ggtgcctgtc cccgggggcg ccatggcgac cggagcgaac gccacgccgt      480

tggacttccc aagtaagaag cggaagagga gccgctggaa ccaagacaca atggaacaga      540

agacagtgat tccaggaatg cctacagtta ttccccctgg acttactcga gaacaagaaa      600

gagcttatat agtgcaactg cagatagaag acctgactcg taaactgcgc acaggagacc      660

tgggcatccc ccctaaccct gaggacaggt ccccttcccc tgagcccatc tacaatagcg      720

aggggaagcg gcttaacacc cgagagttcc gcacccgcaa aaagctggaa gaggagcggc      780

acaacctcat cacagagatg gttgcactca atccggattt caagccacct gcagattaca      840

aacctccagc aacacgtgtg agtgataaag tcatgattcc acaagatgag tacccagaaa      900

tcaactttgt ggggctgctc atcgggccca gagggaacac cctgaagaac atagagaagg      960

agtgcaatgc caagattatg atccggggga aagggtctgt gaaagaaggg aaggttgggc     1020

gcaaagatgg ccagatgttg ccaggagaag atgagccact tcatgccctg gttactgcca     1080

atacaatgga gaacgtcaaa aaggcagtgg aacagataag aaacatcctg aagcagggta     1140

tcgagactcc agaggaccag aatgatctac ggaagatgca gcttcgggag ttggctcgct     1200

taaatgggac ccttcgggaa gacgataaca ggatcttaag accctggcag agctcagaga     1260

cccgcagcat taccaacacc acagtgtgta ccaagtgtgg aggggctggc cacattgctt     1320

cagactgtaa attccaaagg cctggtgatc ctcagtcagc tcaggataaa gcacggatgg     1380

ataaagaata tttgtccctc atggctgaac tgggtgaagc acctgtccca gcatctgtgg     1440

gctccacctc tgggcctgcc accacacccc tggccagcgc acctcgtcct gctgctcccg     1500

ccaacaaccc acctccaccg tctctcatgt ctaccaccca gagccgccca ccctggatga     1560

attctggccc ttcagagagt cggccctacc acggcatgca tggaggtggt cctggtgggc     1620

ccggaggtgg cccccacagc ttcccacacc cattacccag cctgacaggt gggcatggtg     1680

gacatcccat gcagcacaac cccaatggac ccccaccccc ttggatgcag ccaccaccac     1740

caccgatgaa ccagggcccc caccctcctg ggcaccatgg ccctcctcca atggatcagt     1800

acctgggaag tacgcctgtg ggctctgggg tctatcgcct gcatcaagga aaaggtatga     1860

tgccgccacc acctatgggc atgatgccgc cgccgccgcc gcctcccagt gggcagcccc     1920

caccccctcc ctctggtcct cttcccccat ggcaacaaca gcagcagcag cctccgccac     1980

cccctccgcc cagcagcagt atggcttcca gtaccccctt gccatggcag caaaatacga     2040

cgactaccac cacgagcgct ggcacagggt ccatcccgcc atggcaacag cagcaggcgg     2100

ctgccgcagc ttctccagga gcccctcaga tgcaaggcaa ccccactatg gtgcccctgc     2160

cccccggggt ccagccgcct ctgccgcctg gggcccctcc ccctccgccg cctccaccgc     2220

ctggttccgc cggcatgatg tatgccccgc cccctcctcc tccgcctccc atggaccctt     2280

ctaactttgt caccatgatg ggcatggggg tggcgggcat gccgcccttc gggatgcctc     2340

cagctccccc accgcctcca ccacagaact agacttgttt tttaagaaaa tatatattat     2400

atatagagag aattggtctc gtttaaacac gccgaacctc accatatgga gccagacatt     2460

gggacgcacg catgtgattg tgtgtgcacg catgtgtgtg tgtgcacgca ctgggctggg     2520

ccaagcgact gaggattcgc ttgggaacgg gcaggtggta gtaggggcgc cagcttgggc     2580

tctcctggcg ccccgtagca tcgagtgtct tctttgtctt ctttctctcc tcacccaact     2640

ccctttgcct ctccccaaac cgggccgcca ggatccctcc ccgcggcggc gatggcccga     2700

gccatgagag tgaggacttt ccgcgcccat tggtgaccct tccaggcaga cagcctcagc     2760

aacgcccctg gtggacagga tggttcggca aagcagcctg agttattttt gtggacggaa     2820

tcggaacacg ctggctccat atcgtgaaat ttttattaat ttttttcttt ttcctttgtt     2880

acttctttat cttttccttt cttcagactc cgtccaagga gatgctctcc ccggtcttct     2940

gctgcaattt agattccttt cccttctctc cagttctcct tcccttacca aggagagggg     3000

agcaaatggt tttgggcaag ggctttggcc attcatgtca agctggttgt gggtttttca     3060

aggtgccata gccaccccca aagatgtttg tttaaagcgt ggggtttttt aatctctgcc     3120

acccttgtca agggagtctt gtaaagttgc cgagggtagg ttcatctcca ggtttcggga     3180

ttcccatccg tcctggcgat cctgccagca gtgggtgggc agcctgagct ccctcgggct     3240

cgcctgccag cctggagttc ttcctgtgct ccttgatcac ctgagctgcc tcagattcca     3300

tttggtcctc tccttcctgg aaggcttcct tttatgtttt gttttaatcc caaatgtctg     3360

aatgttttgc agtgtgtagg ggtttgagcc ccttgttcat tctccttcct ttttcctccc     3420

gcttccctct ccatgaagtg attctgttga caataatgta tactgcgcgt tctcttcact     3480

ggtttatctg cagaaatttc tctgggcttt tttcggtgtt agattcaaca ctgcgctaaa     3540

gcggggatgt tccattgaat aaaagagcag tgtggttttc tgggtc                    3586


<210>  592
<211>  1405
<212>  DNA
<213>  homo sapiens

<400>  592
tttcccggcg tccatttagt ggcgggaaaa gcgacctttt ctgagcgcgt ttgcctgttg       60

agtggtagcc tttcccctca accagcaatg gaggagcagc cccagatgca agacgccgac      120

gagcccgcgg actccggagg ggaaggccgg gcaggcgggc caccgcaggt cgccggcgcc      180

caggcggcgt gcagcgagga ccgcatgacc ctgctcctca ggctgagagc acagacaaaa      240

caacaactct tagaatataa atcaatggtt gatgcaagtg aagaaaaaac tccagaacaa      300

attatgcaag aaaagcaaat cgaagctaaa attgaagacc tggaaaatga aattgaagag      360

gtaaaagttg cttttgagat aaaaaagctt gcattagaca ggatgagact ttcaactgca      420

cttaaaaaaa acctggagaa aattagcaga cagtctagtg tgctcatgga taacatgaaa      480

cacctattag agctaaataa attaataatg aaatcacagc aggaatcttg ggatttagag      540

gaaaaactgc ttgatattag aaagaagaga ttgcaattaa aacaagcttc agaaagtaag      600

cttttagaaa tacagactga aaagaacaaa cagaagattg atttggacag tatggaaaac      660

tcagagagga taaagatcat acgacaaaac ctacagatgg agataaaaat tactactgtt      720

attcaacatg tgttccagaa ccttattttg gggagtaaag tcaattgggc agaggatcct      780

gcccttaagg aaattgttct gcagcttgag aagaatgttg acatgatgta ataagaattc      840

atttctgaca tattttacat ttctggcaat ctcaactctt atttggaata cttctgtgca      900

tttgtctgtc caccgtaatt ttagaaaagc atatccataa cgtttacagt tgtagtacag      960

ttgtggttag ttatttgtag tgggattgaa agtaattttt ttctttttat atttctatat     1020

ttagtttgtt tttttgttgt tgttgttttt tgagatggag tctcgctttg ttgcccagac     1080

tggagggcag tggcgcgatc tcggctcact gcaacctctg cctcccgggt tcaagcagtt     1140

ctgcctcagc ctcccaagta gctgtgacta aaggtgcacg ccgccatgcc cagctaattt     1200

tttgtatttt agtagagacg gggtttcacc gtgttgccca ggctgctctc agaactcctg     1260

agctcaggca gtccaccgcc tcggcctacc gaagtgctag gattacagac gtaagccacc     1320

gagcctggtc tagtttgcat tttttttcta tcagttttat aagttaagaa ataaaaggaa     1380

ttaatgttaa aaaaaaaaaa aaaaa                                           1405


<210>  593
<211>  3384
<212>  DNA
<213>  homo sapiens

<400>  593
gtgagttcca ggtgggaagg cagttatgac agttgagaag tagtagaaga cacggaaggc       60

acagaaggca gacttcgctc agcacaaaga attttctgat aaccatactg gcaaaatgaa      120

ctgggctgcc ttcggagggt ctgaattctt catcccagaa ggcattcaga tagattcgag      180

atgcccacta agcagaaata tcacggaatg gtaccattac tatggcattg cagtgaaaga      240

aagctcccaa tattatgatg tgatgtattc caagaaagga gctgcctggg tgagtgagac      300

gggcaagaaa gaagtgagca aacagacagt ggcatattca ccccggtcca aactcggaac      360

actgctgcca gaatttccca atgtcaaaga tctaaatctg ccagccagcc tgcctgagga      420

gaaggtttct acctttatta tgatgtacag aacacactgt cagagaatac tggacactgt      480

aataagagcc aactttgatg aggttcaaag tttccttctg cacttttggc aaggaatgcc      540

gccccacatg ctgcctgtgc tgggctcctc cacggtggtg aacattgtcg gcgtgtgtga      600

ctccatcctc tacaaagcta tctccggggt gctgatgccc actgtgctgc aggcattacc      660

tgacagctta actcaggtga ttcgaaagtt tgccaagcaa ctggatgagt ggctaaaagt      720

ggctctccac gacctcccag aaaacttgcg aaacatcaag ttcgaattgt cgagaaggtt      780

ctcccaaatt ctgagacggc aaacatcact aaatcatctc tgccaggcat ctcgaacagt      840

gatccacagt gcagacatca cgttccaaat gctggaagac tggaggaacg tggacctgaa      900

cagcatcacc aagcaaaccc tttacaccat ggaagactct cgcgatgagc accggaaact      960

catcacccaa ttatatcagg agtttgacca tctcttggag gagcagtctc ccatcgagtc     1020

ctacattgag tggctggata ccatggttga ccgctgtgtt gtgaaggtgg ctgccaagag     1080

acaagggtcc ttgaagaaag tggcccagca gttcctcttg atgtggtcct gtttcggcac     1140

aagggtgatc cgggacatga ccttgcacag cgcccccagc ttcgggtctt ttcacctaat     1200

tcacttaatg tttgatgact acgtgctcta cctgttagaa tctctgcact gtcaggagcg     1260

ggccaatgag ctcatgcgag ccatgaaggg agaaggaagc actgcagaag tccgagaaga     1320

gatcatcttg acagaggctg ccgcaccaac cccttcacca gtgccatcgt tttctccagc     1380

aaaatctgcc acatctgtgg aagtgccacc tccctcttcc cctgttagca atccttcccc     1440

tgagtacact ggcctcagca ctacaggagc aatgcagtct tacacgtggt ctctaacata     1500

cacagtgacg acggctgctg ggtccccagc tgagaactcc caacagctgc cctgtatgag     1560

gaacactcat gtgccttctt cctccgtcac acacaggata ccagtttatc cccacagaga     1620

ggaacatgga tacacgggaa gctataacta tgggagctat ggcaaccagc atcctcaccc     1680

catgcagagc cagtatccgg ccctccctca tgacacagct atctctgggc cactccacta     1740

tgccccttac cacaggagct ctgcacagta cccttttaat agccccactt cccggatgga     1800

accttgtttg atgagcagta ctcccagact gcatcctacc ccagtcactc cccgctggcc     1860

agaggtgccc tcagccaaca cgtgctacac aagcccgtct gtgcattctg cgaggtacgg     1920

aaactctagt gacatgtata cacctctgac aacgcgcagg aattctgaat atgagcacat     1980

gcaacacttt cctggctttg cttacatcaa cggagaggcc tctacaggat gggctaaatg     2040

actgctatca taggcatcca tatttaatat taataataat aattaataat aataataaac     2100

ccaacaccca tcccccagaa gactttatct ctatacattg taactcatgg gctattccta     2160

agtgcccatt ttcctaatga acatgaggat gggatcaatg tgggatgaat aaactttagt     2220

tcagaaacag gacttactaa aagtcagtgg gactgggttt ctgtagccaa gccagacttg     2280

actgtttctg tagagcacta tctcgggcag gccattctgt gccttttccc tctgttccat     2340

gactttgctt tgtgttggca accacttcta gtaagctact gattttcctg ttgacaaaat     2400

ctctttagtc ttgaaggatg gatactggag acagaatctg gtttgtgttc ttggatgggc     2460

acataattta ccaagagcat tcaccttgcc atctgtcttg tcattgtact gtacaaggaa     2520

cagccctcag acgtgttctg cacatccctt cttcctggtg gtaccatccc tatttcctgg     2580

agcaccaggg ctaaatgggg agctatctgg aaactctaga ttttctgtca tacccacatc     2640

tgtcacagta cctgcattgt cttggaatgt aagcactgtc ttgagggaag gaagaggtct     2700

gttctgtatt gccttaagtt gattgaggtt tgtaggagac tggttcttct acatacaagg     2760

atttgtctta agtttgcaca atggctagtg tcagcaaaag gcaggagagg gtttttgttt     2820

tttttttaag ttctatgaga atgtggattt atggcattga gtatcacact cagctctgct     2880

gtgttaactt tgtgaaactg gatggaacaa actttaactt accaagcacc aagtgtgaaa     2940

gtgactttca cggttccttc ataaaactat aataatatcc gacactttga tagaaaaaaa     3000

ttcaaagctg tgcctttgag cctatactat actgtgtatg tgtggaaata aaaatgtatt     3060

gtacttttgg agaatttttt gtaggcattt ttctgtcaga tttgtagtaa tttgtgaggt     3120

ttgttagaga ttaatatagg ttttctttct gtattataaa atgcaccaag caattatggt     3180

ggacctatta ccctatgggt aagaaataaa tggaaatatg acatcggatg tttcagcaac     3240

tgttctgtaa ataaaatctt tgatcacacc actcagtgtg ataattgtgt ctacagctaa     3300

aatggaaata gttttatctg tacagttgtg caagatatga atggtttcac actcaaataa     3360

aaaatattga aacgacaaaa aaaa                                            3384


<210>  594
<211>  2371
<212>  DNA
<213>  homo sapiens

<400>  594
gcctcgcctc ggcgccgcgg ccggcatttc tcctcgcagc tcgctgcctc ctctatccct       60

gcctccctct cccccctctg tttttctccc ttccttccct ctccgaccct cttcctctcc      120

ctcccgatcc tttccctcct cctctcatct ttcccctgtc tctccgttct agctcgtccc      180

ccaccccacc ttttcttctt tctcctcctc tccttcctct ccccctctcc tctgtctcct      240

tccaccgtct cccctgcctc cctgtctttc agtccctgtt tttcagcccc gtctccctct      300

cggtttctct cccccaccct ccctccgggt ttcctccccg gtgccctccc tcctctctcc      360

ctcccctccc cctccgcccc tcgcagcccc gccgctcgca gctcccagtc tgcctccccg      420

aaccggcgcc gccgcccgca ctcgccgcag gaccggcccg cccggctccc ggggtgcgcc      480

ctcctcggtc ccgcgccctc cgggctcgca gggacgtctc ctccctcccg gctcgcggcc      540

ccgcccggcc cggcccccgc ccagagcccc agcgcgccga ggatgtgagt cctgctcgcc      600

tctggcggag cagcagccac tcgcgcgcgg agccggagcg cagcgcagcg cagccgcggg      660

cgctctccgg gccgctcgcg cgagtgccgc gctcttgccc tagcggcgtc ccccggcctc      720

tcgccggcgc caccgccgca gcagcccgcg ggccgtcccc ggccggccgc ccccggcccc      780

agcgccgctg accctgtccg ccgcgggcgg ggacgcgggc ggaggaggcg ccgcggcgga      840

gcccccggac gcgaccatgt cggaggtgct gccctacggc gacgagaagc tgagccccta      900

cggcgacggc ggcgacgtgg gccagatctt ctcctgccgc ctgcaggaca ccaacaactt      960

cttcggcgcc gggcagaaca agcggccgcc caagctgggc cagatcggcc ggagcaagcg     1020

ggttgttatt gaagatgata ggattgatga cgtgctgaaa aatatgaccg acaaggcacc     1080

tcctggtgtc taactccccc aaagacaatg agttaaggga gagaataaga acggcggtaa     1140

cagttattgg caaaaagcat gaaaagagaa agcactttga aatttattac tagcttgcta     1200

cccacgatga aatcaacaac ctgtatctgg tatcaggccg ggagacagat gaggcgagag     1260

gaggaggagg aggaggagaa ggctctgggc tcctctgcaa aaataaaaat aaaaaaataa     1320

ataaaatttt aaaaataata aaaattcact atatacacat ataaagaaat aaaaagaagt     1380

ctcagttgca gctatttgtc aaaattaata tccatttctt tttatatacg gtgaatattg     1440

cgcaattata gatctggatt ttgaaccact taatgaagcg gcaacaccag gtgttttgag     1500

gtgttggcat tcttcgctga tttggctgtt cccaatgttt acattattta atcttgcaaa     1560

aatggttctg tgcacttgga tgtgaaatgc tgtccagttt tatttttttt atgttgttat     1620

ccttggatgt acaaaaaatt cagaaaatga tctctgtaga tattctgttt tattttggtc     1680

atctttagaa gttatcagga atgtgtttaa aacaagaaga gaacttttct aaggaatgat     1740

acatagaaaa gattttattt taaaatgagt tgtaaagctt gtgtttcttt gttgctgcaa     1800

gctatctgcc caagttaatg caaatggaca cattttttat gtcagaaaaa cacacacaca     1860

cacacacaca cacacacaca cacacgaaaa acaaagaaaa aaatgcttga gctttttcta     1920

acttcccctt gcagtctgtt gtgtgagcag cctgtttatt tctctaatat tatgtcagtt     1980

tattctcttt aatggactgt aaaaaaatgt aatcacaaga gtgccaaata tcttgaaatg     2040

ccaaaaggca ttttagtttc ttttctctgt gctctgagtc cacgtacagg aatgcttgga     2100

gtgtcttttc tgttatttat agggattctc ttaaggcaca ccagctgcct gttttgcatg     2160

gtatttgcaa aaatgcctct tgcgtgagga aatcttttac cattttttgt ttgcaacttt     2220

ggacctcaag aggtttccct tcccttcccc gttccctctt ttcttaattc aatattctgt     2280

atgttgcacc ttgaaccagc acacagggct atttctccaa tgtacaataa aagaattgtt     2340

cctgtgtctc aaaaaaaaaa aaaaaaaaaa a                                    2371


<210>  595
<211>  3080
<212>  DNA
<213>  homo sapiens

<400>  595
tcccctttat ttccactccc cacccgcgtg gctttgctct ccctctcccc cctcagctcg       60

tctgtatttg gagctccgga agctgccggc gactctcccc tggagcagcg tgactgacac      120

cggctcctat tcagctggga ggagggagag gggaggagaa ggggagggcc gcgggaggag      180

ggtacgagtg gccgaccacg gatttgcatt gccgaggacg ggaccccagg gcagcgaagc      240

agaatggcca acatgcaggg actggtggaa agactggaac gagctgtcag ccgcctggag      300

tcgctgtctg cagagtccca caggccccct gggaactgcg gggaagtcaa tggtgtcatt      360

gcaggtgtgg caccctccgt ggaagccttt gacaagctga tggacagtat ggtggccgag      420

tttttaaaga acagtaggat ccttgctggg gacgtggaga cccatgcaga aatggtgcac      480

agtgctttcc aggcccagcg ggctttcctt ctgatggcct ctcagtacca acaaccccac      540

gagaatgacg tggccgcact tctgaaaccc atatcggaaa agattcagga aatccaaact      600

ttcagagaga gaaaccgggg gagtaacatg tttaatcatc tttcggccgt cagcgaaagc      660

atccctgccc ttggatggat agctgtgtct cccaaacctg gtccttatgt caaggagatg      720

aatgacgctg ccacctttta cactaacagg gtcttaaagg actacaaaca cagtgatttg      780

cgtcatgtgg attgggtgaa gtcatatttg aacatttgga gtgaacttca agcatacatc      840

aaggaacacc acaccacggg cctcacatgg agcaaaacag gtcctgtagc atccacagta      900

tcagcgtttt ctgtcctctc ctctgggcct ggccttcctc caccccctcc tcctctgcct      960

cctccagggc cacctccact tttcgagaat gaaggcaaaa aagaggaatc ttctccttca     1020

cgctcagctt tatttgccca acttaaccag ggagaagcaa ttacaaaagg gctccgccat     1080

gtcacagatg accagaagac atacaaaaat cccagcctgc gggctcaagg agggcaaact     1140

caatctccca ccaaaagtca cactccaagt cccacatctc ctaaatctta tccttctcaa     1200

aaacatgccc cagtgttgga gttggaagga aagaaatgga gagtggagta ccaagaggac     1260

aggaatgacc ttgtgatttc agagactgag ctgaaacaag tggcttacat tttcaaatgc     1320

gaaaaatcaa ctattcagat aaaagggaaa gtaaactcca ttataattga caactgtaaa     1380

aaactcggcc tggtgtttga caatgtggtg ggcattgtgg aagtgatcaa ctcccaggac     1440

attcaaatcc aggtaatggg gagagtgcca acaatttcca ttaataagac agaaggttgc     1500

cacatatacc tcagtgaaga tgcattagac tgtgagatcg tgagcgccaa gtcatctgaa     1560

atgaacatac ttatccctca ggatggtgat tatagagaat ttcccattcc tgaacagttc     1620

aagacagcat gggatggatc caagttaatc actgaacctg cagaaattat ggcctaactt     1680

cctgagagac cgaaccccct cacctgaatc cccctctatc aaacaaacaa aaaagcagca     1740

gtaaagagct agaagttgca gtagccccta ctgctttagc tttggcctcc aacgattctg     1800

tgctatagat acagcactgt ttctggcacg cctcgtgggc attttgaaat atttaacgtt     1860

tcctcatgat ttgcctttgt gtgtgatttt agttccacat gatgacttgt gaacattagg     1920

gatttaaagg aaaaaaaaaa agaattctgt tcccctcata tcatgaacac agtaactgat     1980

aggtaaaaag actgcatgat tcacttttac acttatattt cattgctagt taaaaaataa     2040

aacctttgag aatctaagat gtacattttt accttttagg caatttcaat ataatgtaga     2100

agtagtagtg tgccctgaaa aatgtacacg ttttttctta ttgttaccac atgttcacct     2160

ttatcagcgt ggatactgtc agcatgagta catatttcaa cccacgcttg taaaagacat     2220

aagagtttat aaaggaccaa attcagttcc ttggtccttg gaagacctat attctctgta     2280

gttactgaaa accgaaagtc aattctaatt attcatctta catatttttc caccatgtca     2340

tttgaaaact tgcttttctt ctgcataaga gattcttatg ccaaaaacat taaacagaag     2400

aaatcatttt ttttgctatg taatacctcg caactttgct ctaaaatcaa gctcagttat     2460

tattttccaa gtttgaacat gttaaatatc agatgccttg taaattatgt ctttaacgtt     2520

ttcttataga ctaatttcct cttttccacc tgccagactt gctaaccaag ctcgaaaatg     2580

aacatgaaaa agccatacat gtattatttc tcctaaaacc taaggcatta tctgttggtt     2640

tggcttgctg ctcctatttt gtagtcttga tagtagatgc ttcttcagcg taagagtagc     2700

tatgatattc ctttttatct tttcagtaca tagtgctgaa aaatctgcaa cttcttggat     2760

catatttaat gaattatagt ataatgcttg caggcccagt acaagcatat atattgtgcc     2820

tcttacagcc tttggaatac attgtttcca ttttttaaat atcttctata tccatatagt     2880

attcaaatta ttaatgctca tgtaccaagg ttttgctata aaagttttgt ctgtatgaat     2940

aatgtggctt tagtaaataa tcatttttca actgtaaact tattctgaaa taaagtaaaa     3000

ttctaattgt ttaaatactg tgatgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa                                                 3080


<210>  596
<211>  5160
<212>  DNA
<213>  homo sapiens

<400>  596
gcagactaga cgctgagcgc tcccgtgcgc agcgccccac gcagccggga cgcggcgccg       60

ctctgcgggt ggaaccgccg cgcgctcccg gcctcgggag ctgagcccga gagaacttcg      120

ctgccttcgg gtcgccgctc ccgctttcca ctgtggaatg tgcagcttgg gatagagaga      180

aaccagggtt tggggagcgg tcctcctgga gactttctct ctgcaagtct ccaaggttaa      240

gcaattctga cccactggaa ttcccagagc ctgggagtta agcctaaaac gctctgttgc      300

tttaagcggc gcggtgggga gtcgctggac actccttatt ttggttttac attaaaaaga      360

aggcggacga gaagatgttg taggtgactt cctagctgtg ttaagttgct cctgggctgt      420

gaatggtgtt aatttctgaa gtgggcggct ccaaaaactt aacaaggaaa gctcaggtaa      480

cggaggcctt ggaaagagac tctgcgtcag gtcacccagc agagatcagc aatccttggc      540

tcactgagga ggtttggatt tgcctcaaag ggcactgcaa aaattgaaca gaggaatccc      600

aaggaagctg cctgaatttg cctgtatact ctcgttctgc gacttataaa ggaccagaca      660

aatcaaatta gtggttttgg tttccgccag ctgtggatgc ctttgacatt atgaccgcag      720

aggattccac cgcagccatg agcagtgact cggccgccgg gtcctccgcc aaggtgcccg      780

agggcgtggc gggcgcgccc aacgaggcag cactgctggc gctgatggag cgcacgggct      840

acagcatggt gcaagagaac gggcagcgca agtacggcgg cccaccgccc ggctgggagg      900

gcccgcaccc gcagcgtggc tgcgaggtct tcgtgggcaa gatcccgcgc gacgtgtacg      960

aggacgagct ggtgcccgtg ttcgaggccg tgggccgcat ctacgagctg cgcctcatga     1020

tggactttga cggcaagaac cgcggctacg ccttcgtcat gtactgccac aagcacgagg     1080

ccaagcgcgc agtgcgtgag ctcaacaact acgagatccg cccgggccgc ctgctcggcg     1140

tgtgctgcag cgtggacaac tgccgcctct tcatcggcgg gatccccaag atgaagaagc     1200

gcgaggaaat cctggaggag attgccaagg tcaccgaggg cgtgctggac gtgatcgtct     1260

acgccagcgc ggccgacaag atgaagaacc gcggcttcgc cttcgtggag tacgagagcc     1320

accgcgcggc tgccatggct cgccgcaagc tcatgcctgg ccgcatccag ctgtggggcc     1380

accagatcgc cgtggactgg gccgaacctg agatcgacgt ggacgaggac gtgatggaga     1440

ccgtgaagat cctctacgtg cgcaacctca tgatcgagac caccgaggac accatcaaga     1500

agagcttcgg ccagttcaac cccggctgcg tggagcgcgt caagaagatc cgcgactacg     1560

ccttcgtgca cttcaccagc cgcgaggatg ccgtgcatgc catgaacaac ctcaacggca     1620

ctgagctgga gggctcgtgc ctggaggtca cgctggccaa gcccgtggac aaggagcagt     1680

actcgcgcta ccagaaggca gccaggggcg gcggcgcggc tgaggcagcg cagcagccca     1740

gctacgtgta ctcctgcgac ccctacacac tggcctacta cggctacccc tacaacgcgc     1800

tcattgggcc caacagggac tactttgtga aagcaggcag cataagaggc cgagggcgag     1860

gtgcagctgg caacagagcc ccagggccta ggggttccta cctcggggga tattctgctg     1920

gccgtggtat atatagccga tatcatgaag ggaaaggaaa gcagcaagaa aaaggatatg     1980

aactggtgcc gaatttggaa atccctaccg tcaacccagt tgccattaaa cctggtacag     2040

tagccatccc tgccattggg gctcagtatt ccatgtttcc agcagctcca gcccctaaaa     2100

tgattgaaga tggcaaaatc cacacagtgg agcacatgat cagccccatt gctgtgcagc     2160

cagacccagc cagtgctgct gccgccgcag ccgcggccgc agccgccgca gccgctgtca     2220

ttcccactgt gtcgacgcca ccacctttcc agggccgccc aataactcca gtatacacgg     2280

tggctccaaa cgttcagaga attcctactg ccgggatcta cggggccagt tacgtgccat     2340

ttgctgctcc agctacagcc acgatcgcca cactacagaa gaacgcggca gccgcggccg     2400

ccatgtatgg aggatacgca ggctacatac ctcaggcctt ccctgctgct gccattcagg     2460

tccccatccc cgacgtctac cagacatact gaggctggtg accagcacga agacagacca     2520

cacaaacacc actgaaggaa cgcttgacta tttatgaaga aggaacatgt tggattcaca     2580

catgcaacct gaaagtgaag aatgttagca gatttatttc tgaattattt tatatacatg     2640

aagttttcac tagtttttta agactatttt caacttagca tgcctacgtt catacatttc     2700

caaaagactt gcaatggttc gtgccttcat tccatctttt aaaaatttgt atgctgtact     2760

acatttgtat agaggttttt gttgttgttt ttttaaggat atattttcag tatgaaggtt     2820

attttcttaa cttctgcact ccagagattt ctattttgta gtaccttcaa taatatatca     2880

actatatatt aaaaaagcac acttgaggag ctagggaact attttgaaaa atatatacaa     2940

tatttaaaga tacaaacagt agtgcttaaa aatactacat aaagcattat tttaaaggtt     3000

atactggaaa gtgcaatttt aaaatgagta aaacctctgt atttctgctg gcattaaggg     3060

ttgatggtgt taccatgtat catcatggcg gtactatttt ttaaaagaaa ttaaacactg     3120

gatctctcct taagccaaca ttgaaaagac ttgccgcact tctgagtcca aacactggaa     3180

agctctcctt tgccaccgtt agccggggct cattctccat gtgccttagc cttaaacatg     3240

cccccactcc cacatctctc accctgtccc ctcctcccca gattcccaat cccaccgcaa     3300

tgtttggcaa gcctaggact gataagtagc tctgatagag gagctggtgg cttttatact     3360

tcttcctggg tttttgttgg ggtttgttgt ttcgttgttt tttgtttttt tttttgtttg     3420

gttggggaag tattgtcttc tacgtgtgct attttcagta gcagagtaag cacaaggttt     3480

taatcgagtt gcataagaca cctttgcata gctatttaat tgcccaatgt aaaactttaa     3540

tgccatttct aatgctttta ttcatttttg aagtatgagt ttgtagggac aaagaatgta     3600

tgttatcgta gacaagaccc ccagagactc ttttcagcag aaagttatgc ttctagttgc     3660

cttaccatgt ttcttgcaaa actgtccatg gtcctcaagg gtgttggaaa cattatgttt     3720

attaaatggg cctctcttcc tttgctgtgc acttgatggg tgaactggat tggggtgtgc     3780

acatccagga ggaggaggag agacctgtag aagtttaaag atagtttgta aatatcttct     3840

aatgcttgtt tttagtcctt ttatgttgga gaagttcatg gtatgtagtt taatgcaaaa     3900

tgaaaccatt ttatttcaat gttattaaaa aggtttgttt tattaggaag ttaatgtatt     3960

gttgcagtgt tttgtgcctg tttaaaggct tttgtttagc agagtgaatg taaaatacag     4020

taaaatgtta agattgtcat ctacttttta aaaaaaaata tcaacttgga attgtttttt     4080

aaaggctcaa tcaaggaagt gaggtgtgca ataaggtagc aagtaaaacg cagttgcgtt     4140

tttatgtcat gttagagatc catacaattt tccactcacg ggatttttgt tgatggctga     4200

attcttgtgg attcataaga ggatcatgcc cttagcaagt acttttgttt tgttttaaat     4260

taagagattc ccaaatgcct ttttccccct catcttgaaa tgagatgagt ttttatgtgt     4320

aagcaatatt tatttaacta ttctataaaa ttattgagtg cctactgagg cctttaagca     4380

ccgctaacat tcctttccat cattctttta aatgacataa aataattgtg caatgttcct     4440

gatgatgtac cccacaagct gcattcaaac tcaaatctgt gggaatgagt gactcgacaa     4500

aatgtaattc ggatcagatc ctcatcccct gactgtgtga aaaaagtact ctccttctag     4560

tgaaggattg tcacagagtt tcactggatg aaactatgac ccagtattct tactgtattt     4620

tacatatgcc tgtaaattat ttgcaaaaaa gaagaagaag aggaagaaag aaaagaaaga     4680

aaagaaagaa agaaagaaag aaagaaagaa agaaagaaag aaagaaagaa agaaagaaag     4740

aaaaagaaag aaagaataaa aaaaaatgat aacatggcaa ccaccaaact cccttaaaaa     4800

caaacattgg tgacatggcc aattaagtat cagtgagcct cctatctggg acttatctgt     4860

tcctattgtt tcaaaaccat ttcatgtaca ctactgaggt aagtttataa cttgaaatgt     4920

gaactttttt tttttttagt gttaagaaca aactatataa atgtaaaaaa aaagttttag     4980

agttctgttt tcaaacattg ctagtggttt agttaacttt agctgcttta tatttgaaaa     5040

gcttttattt agatcttgct ccatttacag tacattctta ggatgtatgt agtaaataaa     5100

gctttcttta aagcaatcgc aagaccttat tttaaattgt gaaaaaaaaa aaaaaaaaaa     5160


<210>  597
<211>  3271
<212>  DNA
<213>  homo sapiens

<400>  597
gctgtgacag ccacacgccc caaggcctcc aagatgagct acacgttgga ctcgctgggc       60

aacccgtccg cctaccggcg ggtaaccgag acccgctcga gcttcagccg cgtcagcggc      120

tccccgtcca gtggcttccg ctcgcagtcg tggtcccgcg gctcgcccag caccgtgtcc      180

tcctcctata agcgcagcat gctcgccccg cgcctcgctt acagctcggc catgctcagc      240

tccgccgaga gcagccttga cttcagccag tcctcgtccc tgctcaacgg cggctccgga      300

cccggcggcg actacaagct gtcccgctcc aacgagaagg agcagctgca ggggctgaac      360

gaccgctttg ccggctacat agagaaggtg cactacctgg agcagcagaa taaggagatt      420

gaggcggaga tccaggcgct gcggcagaag caggcctcgc acgcccagct gggcgacgcg      480

tacgaccagg agatccgcga gctgcgcgcc accctggaga tggtgaacca cgagaaggct      540

caggtgcagc tggactcgga ccacctggag gaagacatcc accggctcaa ggagcgcttt      600

gaggaggagg cgcggttgcg cgacgacact gaggcggcca tccgcgcgct gcgcaaagac      660

atcgaggagg cgtcgctggt caaggtggag ctggacaaga aggtgcagtc gctgcaggat      720

gaggtggcct tcctgcggag caaccacgag gaggaggtgg ccgaccttct ggcccagatc      780

caggcatcgc acatcacggt ggagcgcaaa gactacctga agacagacat ctcgacggcg      840

ctgaaggaaa tccgctccca gctcgaaagc cactcagacc agaatatgca ccaggccgaa      900

gagtggttca aatgccgcta cgccaagctc accgaggcgg ccgagcagaa caaggaggcc      960

atccgctccg ccaaggaaga gatcgccgag taccggcgcc agctgcagtc caagagcatc     1020

gagctagagt cggtgcgcgg caccaaggag tccctggagc ggcagctcag cgacatcgag     1080

gagcgccaca accacgacct cagcagctac caggacacca tccagcagct ggaaaatgag     1140

cttcggggca caaagtggga aatggctcgt catttgcgcg aataccagga cctcctcaac     1200

gtcaagatgg ctctggatat agaaatcgct gcgtacagaa aactcctgga gggtgaagag     1260

actagattta gcacatttgc aggaagcatc actgggccac tgtatacaca ccgaccccca     1320

atcacaatat ccagtaagat tcagaaaccc aaggtggaag ctcccaagct taaggtccaa     1380

cacaaatttg tcgaggagat catagaggaa accaaagtgg aggatgagaa gtcagaaatg     1440

gaagaggccc tgacagccat tacagaggaa ttggccgttt ccatgaagga agagaagaaa     1500

gaagcagcag aagaaaagga agaggaaccc gaagctgaag aagaagaagt agctgccaaa     1560

aagtctccag tgaaagcaac tgcacctgaa gttaaagaag aggaagggga aaaggaggaa     1620

gaagaaggcc aggaagaaga ggaggaagaa gatgagggag ctaagtcaga ccaagccgaa     1680

gagggaggat ccgagaagga aggctctagt gaaaaagagg aaggtgagca ggaagaagga     1740

gaaacagaag ctgaagctga aggagaggaa gccgaagcta aagaggaaaa gaaagtggag     1800

gaaaagagtg aggaagtggc taccaaggag gagctggtgg cagatgccaa ggtggaaaag     1860

ccagaaaaag ccaagtctcc tgtgccaaaa tcaccagtgg aagagaaagg caagtctcct     1920

gtgcccaagt caccagtgga agagaaaggc aagtctcctg tgcccaagtc accagtggaa     1980

gagaaaggca agtctcctgt gccgaaatca ccagtggaag agaaaggcaa gtctcctgtg     2040

tcaaaatcac cagtggaaga gaaagccaaa tctcctgtgc caaaatcacc agtggaagag     2100

gcaaagtcaa aagcagaagt ggggaaaggt gaacagaaag aggaagaaga aaaggaagtc     2160

aaggaagctc ccaaggaaga gaaggtagag aaaaaggaag agaaaccaaa ggatgtgcca     2220

gagaagaaga aagctgagtc ccctgtaaag gaggaagctg tggcagaggt ggtcaccatc     2280

accaaatcgg taaaggtgca cttggagaaa gagaccaaag aagaggggaa gccactgcag     2340

caggagaaag agaaggagaa agcgggagga gagggaggaa gtgaggagga agggagtgat     2400

aaaggtgcca agggatccag gaaggaagac atagctgtca atggggaggt agaaggaaaa     2460

gaggaggtag agcaggagac caaggaaaaa ggcagtggga gggaagagga gaaaggcgtt     2520

gtcaccaatg gcctagactt gagcccagca gatgaaaaga aggggggtga taaaagtgag     2580

gagaaagtgg tggtgaccaa aacggtagaa aaaatcacca gtgagggggg agatggtgct     2640

accaaataca tcactaaatc tgtaaccgtc actcaaaagg ttgaagagca tgaagagacc     2700

tttgaggaga aactagtgtc tactaaaaag gtagaaaaag tcacttcaca cgccatagta     2760

aaggaagtca cccagagtga ctaagatttg agtccattgc aaaaggttaa gccatatgac     2820

aatttcaaaa tgcatgtgat tggcagcttc aaaacagaac gggttctccc atgggggctc     2880

cagacattgt attttacttt gtgcaatatg aggggactgc atgcaagctc agggtgctcc     2940

ctcctcagtc tttgggggat tcaaatgcat gatattgtat gtacctggga aatttgccga     3000

tttcctaagc tgttggaagg gggtcactta aggggggatg tcttgagatg tattatgcaa     3060

agtaccaact gagccaaaaa caataaacga aacacagaac tcagccttaa gaaagctata     3120

tatgaataat tatgtttacc tcactggtgc atttaaaatg gacttttgtt catgggagaa     3180

cctcgttgac atgcacagtt tgcaatctta tgttgatcga tgttaaacgt cacagcagta     3240

cttgctcaat aaaggtcata ttggaaacat a                                    3271


<210>  598
<211>  777
<212>  DNA
<213>  homo sapiens

<400>  598
gagccattga ttggtcgacg cccccagagg gttacaattc aaacgcgggc gggcgggccc       60

gcagtcctgc agttgcagtc gtgttctccg agttcctgtc tctctgccaa cgccgcccgg      120

atggcttccc aaaaccgcga cccagccgcc actagcgtcg ccgccgcccg taaaggagct      180

gagccgagcg ggggcgccgc ccggggtccg gtgggcaaaa ggctacagca ggagctgatg      240

accctcatgg tatatgaaga cctgaggtat aagctctcgc tagagttccc cagtggctac      300

ccttacaatg cgcccacagt gaagttcctc acgccctgct atcaccccaa cgtggacacc      360

cagggtaaca tatgcctgga catcctgaag gaaaagtggt ctgccctgta tgatgtcagg      420

accattctgc tctccatcca gagccttcta ggagaaccca acattgatag tcccttgaac      480

acacatgctg ccgagctctg gaaaaacccc acagctttta agaagtacct gcaagaaacc      540

tactcaaagc aggtcaccag ccaggagccc tgacccaggc tgcccagcct gtccttgtgt      600

cgtcttttta atttttcctt agatggtctg tcctttttgt gatttctgta taggactctt      660

tatcttgagc tgtggtattt ttgttttgtt tttgtctttt aaattaagcc tcggttgagc      720

ccttgtatat taaataaatg catttttgtc cttttttaga caaaaaaaaa aaaaaaa         777


<210>  599
<211>  5081
<212>  DNA
<213>  homo sapiens

<400>  599
tttcagttgg aaggaggtag ggaaaataag tgctttaatt cctaggattt tggaagtaaa       60

aatggaacac cagacaaaaa tggaattttt aggcaaatgt aaagctttgt acttgggtat      120

ctcaaagtat tatacagtgt aaactatcat gattattaac caactagaag tagttctttt      180

ttttaaattt tatttttaat tttagacatg agggtcttgc tatgttgccc aggctgaagt      240

ggctactgac aggcacgatg tggcactgca gcctggaact cttgggctta agtgatcctt      300

cctgcttctt ctatcttaaa aaaaaaaagt tacgcttgct tgttaaaata tttttaaaat      360

gctgtgttta aactaagaag taaatatcca ccccacctct gacttctaaa aattatctaa      420

agtatgactg gtaagatttt tacctttaat cccacataag tctaaaattt gtgttcattt      480

ccaacaacca aagtgtgtca cttttatacc agaattttgt cctgcttata cgtttagtac      540

agaaatctca tgggagagag catccatgca tttacaaatt gttattgaat tattttattg      600

aatgatgaca cccaaactga gctagaacat aattctggct ctgctagtac atcttctgtg      660

tgatcttgga caagtcactc tactttcctt tcaattttct tttctcacag ggagataatc      720

ataaaaacga ctgtaaagta cagcacttca tagagtgctt tttgtttaaa gagctgacaa      780

taaatacgag tctcaaggtc taggaaagcc tccctcacaa cctgagctgc ttgaggacaa      840

gggattttct tttgaatcag cagtacctta tttgtgtatc tgtgatagag ttcctggtac      900

ataagaaggt ctcaataaat atgtgaattt atgaatatta ggcagattgc aaccttgaca      960

ggccactgcc tcttaaatct cctttctgtg atcttttaat atttaacatc taaaaggccg     1020

ccgctacttg ctttgggata agtatccccg gtatgtactt taaaatgccc aagcctagag     1080

aaatgattct tgtcttaagg gcaccatttc gctctcccac cgtaaagcgc cccaggcttg     1140

ggatctgggt cccaaggcta cagggaagag tttggaacgg gaagctcatc ttccggccct     1200

ctgattggcc ggctcgcact ccactcacgc ggcgcgcagc tctgattggc ctcggcggca     1260

cccctcgtcc cgcgactact ttgtgtgctg gggcggcgcg ctccggtcct cccgctcagc     1320

tggcggtctg ggctgctctg gggcagccct tcggtccact gctctgcatc gcgggcgccg     1380

ggaattttcc gagtccgagc ggcatgtaga gcgcatgaag tacaggacaa taaagcttcc     1440

tacacatatc accaggagga tctctttgaa agattcactg caggactacc agagagaata     1500

atttgtctga agcatcatgt gttgaaacaa cagaagtcta ttcacctgtg cactaactag     1560

aaacagagtt acaatgtttt caattctttg agctccagga ctccagggaa gtgagttgaa     1620

aatctgaaaa tgcggccatg gactggttcc tggcgttgga ttatgctcat tctttttgcc     1680

tgggggacct tgctgtttta tataggtggt cacttggtac gagataatga ccatcctgat     1740

cactctagcc gagaactgtc caagattctg gcaaagcttg aacgcttaaa acaacagaat     1800

gaagacttga ggcgaatggc cgaatctctc cggataccag aaggccctat tgatcagggg     1860

ccagctatag gaagagtacg cgttttagaa gagcagcttg ttaaggccaa agaacagatt     1920

gaaaattaca agaaacagac cagaaatggt ctggggaagg atcatgaaat cctgaggagg     1980

aggattgaaa atggagctaa agagctctgg tttttcctac agagtgaatt gaagaaatta     2040

aagaacttag aaggaaatga actccaaaga catgcagatg aatttctttt ggatttagga     2100

catcatgaaa ggtctataat gacggatcta tactacctca gtcagacaga tggagcaggt     2160

gattggcggg aaaaagaggc caaagatctg acagaactgg ttcagcggag aataacatat     2220

cttcagaatc ccaaggactg cagcaaagcc aaaaagctgg tgtgtaatat caacaaaggc     2280

tgtggctatg gctgtcagct ccatcatgtg gtctactgct tcatgattgc atatggcacc     2340

cagcgaacac tcatcttgga atctcagaat tggcgctatg ctactggtgg atgggagact     2400

gtatttaggc ctgtaagtga gacatgcaca gacagatctg gcatctccac tggacactgg     2460

tcaggtgaag tgaaggacaa aaatgttcaa gtggtcgagc ttcccattgt agacagtctt     2520

catccccgtc ctccatattt acccttggct gtaccagaag acctcgcaga tcgacttgta     2580

cgagtgcatg gtgaccctgc agtgtggtgg gtgtctcagt ttgtcaaata cttgatccgc     2640

ccacagcctt ggctagaaaa agaaatagaa gaagccacca agaagcttgg cttcaaacat     2700

ccagttattg gagtccatgt cagacgcaca gacaaagtgg gaacagaagc tgccttccat     2760

cccattgaag agtacatggt gcatgttgaa gaacattttc agcttcttgc acgcagaatg     2820

caagtggaca aaaaaagagt gtatttggcc acagatgacc cttctttatt aaaggaggca     2880

aaaacaaagt accccaatta tgaatttatt agtgataact ctatttcctg gtcagctgga     2940

ctgcacaatc gatacacaga aaattcactt cgtggagtga tcctggatat acattttctc     3000

tctcaggcag acttcctagt gtgtactttt tcatcccagg tctgtcgagt tgcttatgaa     3060

attatgcaaa cactacatcc tgatgcctct gcaaacttcc attctttaga tgacatctac     3120

tattttgggg gccagaatgc ccacaatcaa attgccattt atgctcacca accccgaact     3180

gcagatgaaa ttcccatgga acctggagat atcattggtg tggctggaaa tcattgggat     3240

ggctattcta aaggtgtcaa caggaaattg ggaaggacgg gcctatatcc ctcctacaaa     3300

gttcgagaga agatagaaac ggtcaagtac cccacatatc ctgaggctga gaaataaagc     3360

tcagatggaa gagataaacg accaaactca gttcgaccaa actcagttca aaccatttca     3420

gccaaactgt agatgaagag ggctctgatc taacaaaata aggttatatg agtagatact     3480

ctcagcacca agagcagctg ggaactgaca taggcttcaa ttggtggaat tcctctttaa     3540

caagggctgc aatgccctca tacccatgca cagtacaata atgtactcac atataacatg     3600

caaacaggtt gttttctact ttgccccttt cagtatgtcc ccataagaca aacactgcca     3660

tattgtgtaa tttaagtgac acagacattt tgtgtgagac ttaaaacatg gtgcctatat     3720

ctgagagacc tgtgtgaact attgagaaga tcggaacagc tccttactct gaggaagttg     3780

attcttattt gatggtggta ttgtgaccac tgaattcact ccagtcaaca gattcagaat     3840

gagaatggac gtttggtttt tttttgtttt tgtttttgtt ttttccttta taaggttgtc     3900

tgtttttttt tttttaaata attgcatcag ttcattgacc tcatcattaa taagtgaaga     3960

atacatcaga aaataaaata ttcactctcc attagaaaat tttgtaaaac aatgccatga     4020

acaaattctt tagtactcaa tgtttctgga cattctcttt gataacaaaa aataaatttt     4080

aaaaaggaat tttgtaaagt ttctagaatt ttatatcatt ggatgatatg ttgatcagcc     4140

ttatgtggaa gaactgtgat aaaaagagga gctttttagt ttttcagctt atttactttg     4200

ttttttttcc tgtttctgat atagtaacta attcttaact cagagacatt ggtccatttt     4260

aatactgaaa accaattttc attggtacac attacaaaat tgctaagaac actgtttggg     4320

agctttcatt ctcatatttt ggacattgtt ttaattgagt gaaataatca taactccttg     4380

ctcccagaga agctatcacc tccatttcta aaaccatttc aggtttgttt ggtagtcttt     4440

cttaatgtat ttattatcgc tttttgtgag tagggtcctg ttttatccag gaaccaattt     4500

ctgccctagc ctatcatgcc ctgcttttga gagtaccagg tatctttggg attgggaagc     4560

tggctgtttc agaagtatat gtctcatagt gtgcagaact tggtgaccaa gtgagaagcg     4620

ggaccaatgg gagactcaca atggactgag tcttgggatt atcttttcca aattcttcca     4680

tgttagaatc acttcagaaa ataagacttt gatgctttgt ctctgagcat catttttctc     4740

ctcataaaaa cacttcctta ttgtatgtag cctgcctcct acagaggcct ggtaggtgtt     4800

actgcattct aaaagaaaaa tgtcatctct gtaggagcga ctatcaggcc tagtgtgaaa     4860

tattagggat cctaggcaga agagctatta gtcctggcct tcatatcttc accaaatgaa     4920

aatactgtat ataaaatttc accaccaaac ttaactaaat tctttttctc aagtcaagcc     4980

tcccaaagaa aaaagaaatt aacttcctac agtgtcagca agcaattttc catttagttt     5040

tggtacaaat aaaagtcatt tgaaacaaaa aaaaaaaaaa a                         5081


<210>  600
<211>  12815
<212>  DNA
<213>  homo sapiens

<400>  600
gcggcagtag ctgtagcagc ttcagcgaag ccggagatgg gcagagagcg cgcgcggcgc       60

agcagctcca gattcactgc tctcccctgc agctccccgc gcccccgccg ctgtcgctgc      120

ctcggtgtcc cccagcccca gtcgcgctct taggacagcg ccgccaccgc cgcctggccc      180

tgcctgcctc ctgcgccgcg cagccctcgc gagcgccccg gatggcgctt tacccctagg      240

accgatttag aatgtaataa ctcaaggatt tgataataca gtgaagtagt ataacaactg      300

tctacgtgct tcccatgata tgttctctat attgaaaaat tatgacatca acatccaaag      360

gaattcttcg cccattttta attgtctgca ttatcctggg ctgtttcatg gcatgtcttc      420

tcatttacat caaacctacc aacagctgga tcttcagtcc aatggaatca gccagctctg      480

tgctgaaaat gaaaaacttc ttttccacca aaactgatta ttttaatgaa actactattc      540

tggtgtgggt gtggccattt gggcagacct ttgaccttac atcctgccaa gcaatgttca      600

acatccaagg atgccatctc acaacggacc gttcactgta caacaaatcc catgcagttc      660

tgatccatca ccgagacatc agttgggatc tgacaaattt acctcagcaa gctaggccac      720

ccttccagaa atggatttgg atgaatttgg aatcaccaac tcacactccc caaaagagtg      780

gcattgagca cttgtttaac ctgactctga cttaccgccg tgattcagat atccaagtgc      840

cttatggctt cttgacggta agcacaaatc ccttcgtgtt tgaagtgcca agcaaagaga      900

aattggtgtg ctgggttgtg agtaactgga accctgagca tgccagagtc aagtattaca      960

atgagctaag caaaagcatt gaaatccata cctacgggca agcatttgga gaatatgtca     1020

atgataaaaa tttgattcct accatatcta cttgtaaatt ttatctttcc tttgaaaatt     1080

caatccacaa ggattacatc acggaaaagc tatacaatgc ttttctggct ggctctgtac     1140

ctgttgttct gggaccatct agggaaaact atgagaatta tattccagca gattcattca     1200

ttcatgtgga agattataac tctcccagtg agctagcaaa gtatctgaag gaagtcgaca     1260

aaaacaataa gttatacctt agttacttta actggaggaa ggatttcact gtaaatcttc     1320

cacgattttg ggaatcacat gcatgtttgg cttgcgatca tgtgaaaagg catcaagaat     1380

ataagtctgt tggtaattta gagaaatggt tttggaatta aaatttttca tcacttgcac     1440

acttgataaa tattttgatg agatatcatc caagtattga ggataagaag agatgcaaca     1500

tactactttt gtgtcacaat ttatttttat caccctctct agggtaacgt gtatattttg     1560

gtggagattt ttaaaagctc agcatgagca atcattccat tcggttttaa attatcctgt     1620

atatacctaa ttatgtgcac tggagagtaa tttattcttc attatcattt gtaaacattg     1680

ttttttcaca tttttgtagt tgtccataat gtaagcttgt ggtttgatta ttgtttccac     1740

actgatcagc tgtttaatct atttgggaaa tgaagatgca catcttaaag tatgaaaaat     1800

tttcactaag tattacaatg tctagttcca actttgcata ctataacaga ggaagaacat     1860

gttgcgattg aattctaacc tctttgactc cgaagatgaa tgaagtgtat aactgtctct     1920

atttgatcta ttttttttac ctgtttatca catttgtgaa ggtgaaatta ttcatggagt     1980

gaataagaaa gatatgaagc agaactgttc tattcgggaa gctattagac ttctcattta     2040

ttttcattaa gctgatttgc agctacttat tctcatggtc ttaaattaaa ttattcaagt     2100

atttttaaat atccaatttg ttgtgatttt cagcacctgg gaagtaatcc caataatact     2160

ttagaaaatc taagacagtt ctttctgcta ctgatgacac tcattgtcat aataaaacaa     2220

ataatttcct caaataacaa agaaaaatga tacctataaa tatatttata aatggtgtca     2280

tttatgaaca atgtttaatt atgtatcaat ttaagatttt tttctgaagc cctaatattt     2340

aaaatggtct tattttacca tatggatata agatttggct cataatgatg agccctatca     2400

tttgatttga gttctatcat ttaagagagc ctaaataaaa ttatcatcaa ggtattaaat     2460

ataagacgtt aaatataata aagtggggat atatagaaaa cacacagtgt tagcacacag     2520

taagatctca atgcacattt gttggatgaa taaataaatg caattgaatt cccagaaaaa     2580

tgattgtttc aaggaagtga cagttctact ttagaagtac taattggaga tgacttttat     2640

atcccatttt ggtaattatt catacatagc acatatgacc atgatgttca gggctttata     2700

gaaccaaata aacctaccat tacatgaaaa ttttgaagag tatattcctg aacttgcagc     2760

tgcctatagc attctcctcc ataaggctag aggagagctg gatataagca gagatcgtag     2820

gtgaaaaaag atgggccatt aaggattctt caaggaaaac attcctcaaa atgatcttta     2880

gtgcctttat tcctttcagg ccaataatcc acccaaaaat tagaatgttc tgagacatcc     2940

atttgggtct atttgtgact tattcgtatt acaaattgac atcagcaaaa ttcaaaaaga     3000

attcagtaaa aagggcatag atccagctat ccagactatc ttgtgagaga ataagctcac     3060

cccagcacca gaaagatttg agcagaggaa tattcctgta atgaatagag gattgtttga     3120

ttctcaggta tatttcttaa gccaagattg aatgcagtgt caggcactgc cttaacaccc     3180

acagagataa gatgaacaag gtactatcac tgcctaaaat gagcttacaa ttaagtggat     3240

agacatataa aagcttcctt tcaattcagc ctgagactgt ttatatgcat gtgctactcc     3300

gaatgacgtt tgtatgggtc aatgctgatt taatggggaa aaaaagtaga aaatttcccc     3360

aattgcttag ctgtttgaca tgtttctgag ctgcaaactt tgtcaactct tttgacccaa     3420

catattattc tctccgtatt atctcttcta accacaatgc attaagaaat aatattttta     3480

tgtggatgtc ctcctcaata agtaaagatc tccatccata tttaattaat tggtaagaca     3540

gtcaaattca tacatttaca tttactttgt caaatttttt ggtctataaa aagcatagag     3600

atctaaagag gatacactgc taacaagttt agaaagcacc tgcttttttt tattattatt     3660

atttttgtga tagagtcttg ctctgtcgcc caggccggag tgcagtggtg cagtctcggc     3720

tcactgcaac ctcggcctcc caggttcaag tgattctcct gtatcagcct cccgagtagc     3780

taggattaca ggcgtgtacc actatgcctg gctagttttt gtatttttag tagagatggg     3840

tttcactgtg ttggccaggc tggtcttgaa ctcctgacct caaatgatcc acttgcctca     3900

gcctcccaaa gtgctgggat tacaggtatg agccactgtg tctggcccac ctgttttttt     3960

tgaaggcaga aaaacattca atattaaaag cattcaatat tatttcaacc tgccttggct     4020

ctagtgaatg ttcatgattt gaaagaactg aaagacctaa aggcagtgtc tctattgttg     4080

actacaaatg taggctcttt gttggactat gactataatc acacactgat aatatgacgc     4140

aagtagaggc agtactacta agtatctagc aggtgctttg aaaccccatt actaagtccc     4200

agaagactgt ttcctaaatt tgaagtggaa gaattaaatg actcaatgga accctttagc     4260

tgtgggtcca ttgatgtgtg agttttagag ctggaaggaa ttataatttt gttgtttata     4320

attgctataa tatagaaatt ataattgctt ttctttctac ttatgagtta actagatcca     4380

gagatattta ttcaagacac acattcacac acacatacac acacacacac acacacccca     4440

cagctagtga caatagttaa gatttggatt taaggatcct atctttcttt atcccacttt     4500

cttttcaatc gcattcataa cttattatag aattatgtct caatttttac aaatgtgaat     4560

gtcttattgg tatttttagg gcctatagaa tggtacacct catgtagaag aacttcgact     4620

tttgaaggta tacaataaat aaaacatcaa acttgttagc attcgttctg gtttaaatat     4680

tttaggagtt gagttcagca gaaggaaatg ggctatcact acatttaagt gaaatacaac     4740

cctcaagaaa gtgtatggtt cacagccact cctttaataa atcctgtggg ttgcaattct     4800

ttgtaagaaa ctcatgaaaa agatatattg attcaacaaa attggtttgc tgttgattat     4860

acaaaccaat aattatgcct agaattaaat tgtggacaca aaaaagggaa cagaccattt     4920

aaaatgtttt atttcaaaat atcgaaaagc tattaccttc aatactctaa atatttaaat     4980

attaattatt gtagacatca gtaagaataa ataaatgtta atcattatag accttactaa     5040

taagaatata tactgaattg tccacatcca gagtattaca ccctgaacaa gaaagacatg     5100

agagcctgac agtcatatat attatgacag ctgtatatct gacaatatga agtagaaact     5160

gaaaaaaaaa atcatcttag tgggaaacaa atacatgctt aaaattgtta tatttactgt     5220

aaaactcctg ataatcttag attgtgcaga aatgtttctt attttgaggg gcttagaaag     5280

ctcagcgcat ttgatgtata aagcaacaga atatttagga attatttgcg gaggctttaa     5340

attcttacct ccaattggag gttaaatatt aaaagaatag gaaactatgc ctctgatatt     5400

ttttttgtca gcctattttt aaactagatt ccatgagtct taaggtaata tcctagaatt     5460

ttttttttgc gtgaattaaa gttaccacaa atttcaggtc cttaccttat gactgtgttt     5520

gatcatatct ttgagttccc ttgaactctg atctcatttt gagaaacatt ttgagaaact     5580

tcttaacaat tacaatcgag ctgttaaata taacaaacat cagaatctaa aggataagca     5640

cagtgcctaa tgtacaggag ggtcatatca aatacttgtt gaataaatac atgaatgtga     5700

taagtggtcc tgtaaaatat tttttaagag tagtgacaat gtttattggt accaattgga     5760

gatgatattt tatatttatt ttgttagttt gtcacctgga tgcaaaagga aggcatttta     5820

attcctttct atcttacaac attgtaaagc atcaaaagaa gtaacatctc aagaaagatt     5880

agaaaggatt tggatcacgt taacattcta tgcaaatatt agtaacatat caactgtttc     5940

taaaaggaaa gaaaattagt atttaaggag agtataaagt gcgagcactg tgaagggcag     6000

atatctatta ccaaaccaca tggagagaaa tatagtctct ctcctaactt cattccattg     6060

tattgcaatc agtcaattaa ggtgattttt tttttctgga tgtctcaatc tagagatttt     6120

gtagcatttt gcaaatgggt atgcttcact actatccaca gtgttctccc ctttagtaat     6180

tcatattgaa tatatccata ttcatatgca ttttataaaa cagttaacag aatctaaata     6240

agatatagcc ggctaaatct ggaatgtgag tgctacccta ggttattagt tcaacaaact     6300

aattttgaga gagccactta acctctctgg accttgtttg taagctttct tctagcacta     6360

ttactcttat ctaagatcga aattgatata tgcatgaaat tcctaatgga atttcaatgt     6420

ccatctcaaa gtaatttttt aggatattcc atacagattt ccttctcatt tctctgtgta     6480

gatatttaaa gtatgaaatt gattatttaa actaatatgt ggaaagaacc taatccagag     6540

cttggaatat agaaagtgct caattaactg acattcctcc tgtatttcct ccctcccctt     6600

agttgtctat gacttttgaa ctcactgctc actgacatct taattgcctg cagaaaaatc     6660

aatcatattt taggcattat tttgaaatat tttagagttt tctgtactat tcaaactctt     6720

attacaaaaa tctaaagata tttattgatg caaaaaattt agggagtcat tggaaatacc     6780

tgaggcaatc ccaggctaac aataaaatag cataatttta agtaagctag attgagttca     6840

tttgaacatt tagttatttt ttagctcata gttaacatat gtccatgcat ttgatttact     6900

ttaaaaatat tttatttaaa aataacctct caaacaccag ttgctttctg tcagttttac     6960

tcaaagcatg cttcctaggt cacctgacct agaatcacca gaagtgttaa caataccgat     7020

ttctgggctt tgagccatga aattagaatt tcttcaaata atccatgccc ccccgtcacc     7080

caaaaaaaga gcatgctttt aatacatttc caaaattatc ctgtttctgc tataactggt     7140

gaaccatcct gtcctaaact agcagttctc aaacatgcat atgcctttga aacttcctag     7200

atcatctaca taaaaatcat ttgaaatatt gttaataata cacagcttct gaatctctgg     7260

gtgtgagatg ggaccaggaa tcttatttta aaaatctccc cagatggttc tggtgtcctg     7320

ctagttttga ggttttcatc ccacctgttt agatgggtag tattctatta aatatgaggt     7380

attacctttc tttagttcac ctggaatctt cttaaatata tcggtaaagt attctacttc     7440

aaaatccaag acattttgta tacctaatta tttcacacaa gagcgtggaa ctcaccagtc     7500

ttgtgacttg gggcaggtta tttatagtct ccagacactt tttccagttg cgagttgctt     7560

atagtagttc gcgaacctga atgcacatta gaaccatctg gagaggcttt aaaattgcag     7620

atgtccaaac cccacctcca gagagctgat ctatttagtt tgaggaagag cccagaagtc     7680

taacaggtgt aaatgttcca caggtaatac taatgcaggc atacctcagg aaatcaccag     7740

ttctcgtctt ggaggaacta ttaggaaaat aaaagattat atatcttgaa aaaaatctct     7800

aatttgcttt ctaggttcta actgcatgtt tatattttgc aacaggaaag actggtctag     7860

acaattacta ggatatatgc ttctgtgatc tgcttttcta ttgtatgtgt ttaagagacc     7920

acattcttgg gttccaaagt ctccttgtct gataggtaat ttgcaattga gatatggcaa     7980

agaattgtag catccaaatt tttgacaact acagatttag aattgaatcc aaggtctgcc     8040

attcactagc tatgtgcaag ttactcaact tctcttatcc tcagattttg cagctgtaaa     8100

gcagaggtag catatttctg agaaattata ttcaggtgac tagatatgtg ttcaagtgtt     8160

atcttttatt cttataaaag ataattgtga ggaatccagt gctattttca caattttaat     8220

tctaaaactc tgaagacatt aaacaggcag tttgtaggaa tcattgaaat tttatacaag     8280

ccgaaggaac aacattcagc aaaacggaaa caaataaata cagcatggaa gcatatattc     8340

atgtttccca taattactaa gttacggaag gggtgtgagg agctggcagt ggtggtgaat     8400

aggcattgtt tgcattacta aatatatata ccatttctta agataattgg aactcaagca     8460

gtcctaattt tctctccctg ttatgagcaa tcagtaaatt tgtagtcaat ttaacttatt     8520

atcagttggt atagcgcatg tcacagaata ggatagcaag aagattctca gagatcattt     8580

tctggtaaag aaaaaggcct agcaatattt aacagtttga cttaatccat cacttcagct     8640

ggtccactag ttttgacaca ggactagtta atgatttgtt aggaagtctc catctactct     8700

taaactaatt taaaaaaaag ctaaaagttg cttttaatat gttagggtat aacttcaata     8760

aacaggagta tttatctagt ggttcagaaa taaaataatt gttagccagc ctgtgattaa     8820

ggctaccata attgcataat aaatagcttt gacgtgaata atctcagttg ttcaagtgta     8880

caaatttaaa gctgtactat gttagaataa aaaagtaggc tcaaggaaaa tttctatttt     8940

tctatatgaa aaagagaatg atattcaaaa tagtattttt aagtagtttc taattgtgtt     9000

cctttaaaga gtattagaaa tgtctgttat gtcagtaaca ttagaaaact tcaaaaactg     9060

atttattttt ctgagttctc tggaaaccaa acaattttga attagttgtg taagtaaagt     9120

aagttaagtt atagcttgct ggaattttat tgtggaaaac aaatatagat tttatctgaa     9180

aaattttaag ggccaattct acagaaagtt atgctaacat gctaactttc cacacatggc     9240

tgcattccat tttgattaat gagggttcag gaaatagaaa ggcagtctct gcagaagcag     9300

tatccaaagg ctaaattaac aacccaggac taccactcat tatgtgagaa atatgggcca     9360

gagttacaat atcacatctc cagtctcaga ttggcctcat tagccacctt cagttcctta     9420

aatgagataa tcctgaagat gccatccttg tccaaggtga gattgccaga ggatatgagc     9480

tcatctagga tggaatacat gtctccaggg actgtaatga gatcaggctt ttcatttact     9540

ggttttctgc ctcaagagtc cttaagcaaa tgaagattat ctgattgtct atgtaaacct     9600

ggaagtagtc tactttttag ataaaagata atctatcttg aatatttcat atgtgatttt     9660

aaaataatta atcaaaaaac aaagactatc atatttgaga acaagatttt acttagaagg     9720

gaaaaaaaag aactttcagc ttaatcgggg ttaagggagt aattgtgaca atataaaatg     9780

gcattgttat agaatcccta aaaggtaaat aatgtatgag atgaaggtag gaagtaatgt     9840

gtgcttgcag aaatgcaact ggtcaaaatt acttgaatga aattgttgag gttaaacatc     9900

ttcattataa taatatgtct tattctgatt ccaagacaat acgaatgtag agaagagatt     9960

tttaaatgga aaaagtaagg agctaacaag tctgtaccta gattcaagtt cacaaagcgg    10020

caaaaaggag aaaagtgtca acaagaaaca agaagaggag tagtaaacta aggatcaaag    10080

cccaagttcc agttttcaca atctgctgta taattcacta acatttctga gccatagatt    10140

tttaatctgt aaaaggagtg tgatggactg tacattagaa gtacctgaga agctcttaat    10200

aaatcttgat gaattggtta gaaattctaa tttaattagc ctggcacagt gcacaaactg    10260

ccatatattc gtgcagatgt tttcttcttt tcttactgcg catttccatg tggccatgtc    10320

actacaaggg gtggggaaga agttaatgtg taattgcttc aggagctctg aataaaaggt    10380

tgctgaagca aaatactgca atgaagttct gaaaatgaag agttaggact ttacatgatt    10440

tctcttgcct cattccctca agaatgcaca tatagacaca catatgccaa tatctttttt    10500

atgtagttca agtataactt tgaataaaat gacttacatt caaggaaggt caaaactatt    10560

attctgaaac aaaatgtgac aattctagcc attatgtgaa ttgtaagggt cagtaatcca    10620

taaattattt ggatggtaat tgtatgtttt attaatgtga tgtaattttg cactattgta    10680

ttgtcatatt taatcaaact cttaaaaata ccctgaaaca taatgccaaa tgtacagttt    10740

ataggttcgt gttatttctg ataagaattt aattgcattg tgctaatagt tgtttattgc    10800

tattaacttt ctgtgtatgt attattgcga tgcagaccca atagggttat tttaagcaca    10860

ctaattagtc atctggattt ttatagataa aatcacatgt tgatcagaaa tcatttttct    10920

acttattttt ttgtagagta tttttccaca cttgaaaaaa acatgattat tttatatcaa    10980

acatcaactt ttctttaaat cttattttag tagctaatgc atgtttgaaa taagatgtgt    11040

tagaaattat atgactatat taaggttgtg tttatattag gtgaaaaatt gcatgcaatt    11100

ggtgaatcat gcagctttgg ggacatttac actgccactc acacacaggc tctgtctcaa    11160

tccgtatgca tgattcacgt cctttcaaaa gtcccttttc aacatttggt aaagtgaaaa    11220

tgttattcat agtgctaatg agccaataaa caatgctgcg tttctttttt ctaactgcag    11280

catattgtgg taaattttct cccaaaactt tatttttgga gttattgttg gcaataaata    11340

caacaaatta tttgttggca agtgatacaa tttactgtat aacaacttaa tagtacaaag    11400

catgaagatg tgaaaatatc atcttaacca gtttcattct atgaacataa tattctggca    11460

gctttttcta taactgagaa tggtatatct ttttatacac tgcctaaatc agtactactg    11520

ccagtcacct gaggtcaggt ctgcacaaca ctaaattggg caataacata gaacatctag    11580

gcagtcttga cagtcaacca gtgtaatcac taggggaaga aaaagtaggc ctaccctttt    11640

acttattaac ttaagtaata aaaattgtat aaaaatatga atgttggctg cagaggagcc    11700

tttacatgca gataatttga agcagtcttt gaaaataaca aaaattattc catttaatga    11760

agggtttgtt ttgtttagct tttctctttt attcagaaaa catacctgtg cttttgaaag    11820

ggcttaatcc caaacaggta atatgtgtgg atcaatcatc tctcctccca tgaaattaat    11880

cattcatggt aatatattaa ggctggaacg tagctcttag tgacttaaaa catgacagta    11940

agcatttaca ctgttggaag gtaatttcat tgctatgtta ttaaaatgat gggaatccta    12000

tttatacatt tatttattta tttatttaca gaagattggt tccttccagt tcaatttaac    12060

agcttcagtg aagttagtat aatgataaga aaaattgact gtagctatta ttccaagtga    12120

aaatcatgca gctgagtcct gctgcatcct gggagcaaag cattaattca aatgaggagt    12180

agtcagtcct agcactgtag acgccgactt taccaaccaa gatagtgtat gtgtgtgaca    12240

ttcagctaac attgatctag gcacttagtt tgctaccaca ttgttccctt cattgattga    12300

aactgtaaat aacataacac tttaaggcag ctaagcaaat attttaataa gccatgaaag    12360

gcaagatgcc agagaaaatc tgtatattca gctatttgga gaactcgtgt tttccacaaa    12420

ttaaactgga gatgtcattt gaaattttct tcccttaaac atgctgtcac aacatggatt    12480

ccttctcatg gatgtctttc taggcttata aatatatggt gtgattgcta taattttgtg    12540

aaattttatt cagcaattaa tagtgatttc agcaatatgt actaagattc caaggcagaa    12600

ataaatgtat aaaggatttg agcctgtatg tgtaagaaga aactctctct tcagtcatat    12660

ttcctaaatt cagtgtaagt acctcgctga tttagcactg gagttattcc ttgaatgtgt    12720

aaataatgat gttctattct gacctaatga attcctgtaa tgtgaatatt taaaataaaa    12780

gaattcaatt taaatgtaaa aaaaaaaaaa aaaaa                               12815


<210>  601
<211>  2153
<212>  DNA
<213>  homo sapiens

<400>  601
aaccgaaaag caacagctga tggcaaatcc gctccggcgc ttgcacgcct cctcggcggc       60

agtctcctgt tgcttctcgg agcttgactg ccctttggaa aaatctctcc gcccctcgag      120

aggagagagg agcagaggac gcgcgcgagc acagagcggg aggacggaca gggagaggag      180

gagagggggt ctgcgcgcgg ccgctaccca gaagccagcg gacggcagca cggagtgggc      240

tgtccccgag cccagccccg agcgagcccc ccccccgccc ccgcaggacg cgcctcccag      300

ccagcccgac tcctaggagg aggggaggcg ggaaagcagc tcaagcctca cccaccgccc      360

tgcccccagc cccgccactc ccaggctcct cgggactcgg cgggtcctcc tgggagtctc      420

ggaggggacc ggctgtgcag gtttgggcct tgacgtggct gtggatgcag tcgttctgac      480

ccctggtggc cgagaggtga agtgcagtgg cggctgcttg ctcaaggccg gaggaagacg      540

ccatggagtt ggtgctggtc ttcctctgca gcctgctggc ccccatggtc ctggccagtg      600

cagctgaaaa ggagaaggaa atggaccctt ttcattatga ttaccagacc ctgaggattg      660

ggggactggt gttcgctgtg gtcctcttct cggttgggat cctccttatc ctaagtcgca      720

ggtgcaagtg cagtttcaat cagaagcccc gggccccagg agatgaggaa gcccaggtgg      780

agaacctcat caccgccaat gcaacagagc cccagaaagc agagaactga agtgcagcca      840

tcaggtggaa gcctctggaa cctgaggcgg ctgcttgaac ctttggatgc aaatgtcgat      900

gcttaagaaa accggccact tcagcaacag ccctttcccc aggagaagcc aagaacttgt      960

gtgtccccca ccctatcccc tctaacacca ttcctccacc tgatgatgca actaacactt     1020

gcctccccac tgcagcctgc ggtcctgccc acctcccgtg atgtgtgtgt gtgtgtgtgt     1080

gtgtgtgact gtgtgtgttt gctaactgtg gtctttgtgg ctacttgttt gtggatggta     1140

ttgtgtttgt tagtgaactg tggactcgct ttcccaggca ggggctgagc cacatggcca     1200

tctgctcctc cctgcccccg tggccctcca tcaccttctg ctcctaggag gctgcttgtt     1260

gcccgagacc agccccctcc cctgatttag ggatgcgtag ggtaagagca cgggcagtgg     1320

tcttcagtcg tcttgggacc tgggaaggtt tgcagcactt tgtcatcatt cttcatggac     1380

tcctttcact cctttaacaa aaaccttgct tccttatccc acctgatccc agtctgaagg     1440

tctcttagca actggagata caaagcaagg agctggtgag cccagcgttg acgtcaggca     1500

ggctatgccc ttccgtggtt aatttcttcc caggggcttc cacgaggagt ccccatctgc     1560

cccgcccctt cacagagcgc ccggggattc caggcccagg gcttctactc tgcccctggg     1620

gaatgtgtcc cctgcatatc ttctcagcaa taactccatg ggctctggga ccctacccct     1680

tccaaccttc cctgcttctg agacttcaat ctacagccca gctcatccag atgcagacta     1740

cagtccctgc aattgggtct ctggcaggca atagttgaag gactcctgtt ccgttggggc     1800

cagcacaccg ggatggatgg agggagagca gaggcctttg cttctctgcc tacgtcccct     1860

tagatgggca gcagaggcaa ctcccgcatc ctttgctctg cctgtcagtg gtcagagcgg     1920

tgagcgaggt gggttggaga ctcagcaggc tccgtgcagc ccttgggaac agtgagaggt     1980

tgaaggtcat aacgagagtg ggaactcaac ccagatcccg cccctcctgt cctctgtgtt     2040

cccgcggaaa ccaaccaaac cgtgcgctgt gacccattgc tgttctctgt atcgtgatct     2100

atcctcaaca acaacagaaa aaaggaataa aatatccttt gtttcctagt ggc            2153


<210>  602
<211>  2229
<212>  DNA
<213>  homo sapiens

<400>  602
aaccgaaaag caacagctga tggcaaatcc gctccggcgc ttgcacgcct cctcggcggc       60

agtctcctgt tgcttctcgg agcttgactg ccctttggaa aaatctctcc gcccctcgag      120

aggagagagg agcagaggac gcgcgcgagc acagagcggg aggacggaca gggagaggag      180

gagagggggt ctgcgcgcgg ccgctaccca gaagccagcg gacggcagca cggagtgggc      240

tgtccccgag cccagccccg agcgagcccc ccccccgccc ccgcaggacg cgcctcccag      300

ccagcccgac tcctaggagg aggggaggcg ggaaagcagc tcaagcctca cccaccgccc      360

tgcccccagc cccgccactc ccaggctcct cgggactcgg cgggtcctcc tgggagtctc      420

ggaggggacc ggctgtgcag agaacttcag ccaaagcatc tgagacggga agcagaaaaa      480

ggagggacag tttggagaag aaaaacgcag ctgtgtgttt gggccttgac gtggctgtgg      540

atgcagtcgt tctgacccct ggtggccgag aggtgaagtg cagtggcggc tgcttgctca      600

aggccggagg aagacgccat ggagttggtg ctggtcttcc tctgcagcct gctggccccc      660

atggtcctgg ccagtgcagc tgaaaaggag aaggaaatgg acccttttca ttatgattac      720

cagaccctga ggattggggg actggtgttc gctgtggtcc tcttctcggt tgggatcctc      780

cttatcctaa gtcgcaggtg caagtgcagt ttcaatcaga agccccgggc cccaggagat      840

gaggaagccc aggtggagaa cctcatcacc gccaatgcaa cagagcccca gaaagcagag      900

aactgaagtg cagccatcag gtggaagcct ctggaacctg aggcggctgc ttgaaccttt      960

ggatgcaaat gtcgatgctt aagaaaaccg gccacttcag caacagccct ttccccagga     1020

gaagccaaga acttgtgtgt cccccaccct atcccctcta acaccattcc tccacctgat     1080

gatgcaacta acacttgcct ccccactgca gcctgcggtc ctgcccacct cccgtgatgt     1140

gtgtgtgtgt gtgtgtgtgt gtgactgtgt gtgtttgcta actgtggtct ttgtggctac     1200

ttgtttgtgg atggtattgt gtttgttagt gaactgtgga ctcgctttcc caggcagggg     1260

ctgagccaca tggccatctg ctcctccctg cccccgtggc cctccatcac cttctgctcc     1320

taggaggctg cttgttgccc gagaccagcc ccctcccctg atttagggat gcgtagggta     1380

agagcacggg cagtggtctt cagtcgtctt gggacctggg aaggtttgca gcactttgtc     1440

atcattcttc atggactcct ttcactcctt taacaaaaac cttgcttcct tatcccacct     1500

gatcccagtc tgaaggtctc ttagcaactg gagatacaaa gcaaggagct ggtgagccca     1560

gcgttgacgt caggcaggct atgcccttcc gtggttaatt tcttcccagg ggcttccacg     1620

aggagtcccc atctgccccg ccccttcaca gagcgcccgg ggattccagg cccagggctt     1680

ctactctgcc cctggggaat gtgtcccctg catatcttct cagcaataac tccatgggct     1740

ctgggaccct accccttcca accttccctg cttctgagac ttcaatctac agcccagctc     1800

atccagatgc agactacagt ccctgcaatt gggtctctgg caggcaatag ttgaaggact     1860

cctgttccgt tggggccagc acaccgggat ggatggaggg agagcagagg cctttgcttc     1920

tctgcctacg tccccttaga tgggcagcag aggcaactcc cgcatccttt gctctgcctg     1980

tcagtggtca gagcggtgag cgaggtgggt tggagactca gcaggctccg tgcagccctt     2040

gggaacagtg agaggttgaa ggtcataacg agagtgggaa ctcaacccag atcccgcccc     2100

tcctgtcctc tgtgttcccg cggaaaccaa ccaaaccgtg cgctgtgacc cattgctgtt     2160

ctctgtatcg tgatctatcc tcaacaacaa cagaaaaaag gaataaaata tcctttgttt     2220

cctagtggc                                                             2229


<210>  603
<211>  2132
<212>  DNA
<213>  homo sapiens

<400>  603
aaccgaaaag caacagctga tggcaaatcc gctccggcgc ttgcacgcct cctcggcggc       60

agtctcctgt tgcttctcgg agcttgactg ccctttggaa aaatctctcc gcccctcgag      120

aggagagagg agcagaggac gcgcgcgagc acagagcggg aggacggaca gggagaggag      180

gagagggggt ctgcgcgcgg ccgctaccca gaagccagcg gacggcagca cggagtgggc      240

tgtccccgag cccagccccg agcgagcccc ccccccgccc ccgcaggacg cgcctcccag      300

ccagcccgac tcctaggagg aggggaggcg ggaaagcagc tcaagcctca cccaccgccc      360

tgcccccagc cccgccactc ccaggctcct cgggactcgg cgggtcctcc tgggagtctc      420

ggaggggacc ggctgtgcag agaacttcag ccaaagcatc tgagacggga agcagaaaaa      480

ggagggacag tttggagaag aaaaacgcag ctgtgtacgc catggagttg gtgctggtct      540

tcctctgcag cctgctggcc cccatggtcc tggccagtgc agctgaaaag gagaaggaaa      600

tggacccttt tcattatgat taccagaccc tgaggattgg gggactggtg ttcgctgtgg      660

tcctcttctc ggttgggatc ctccttatcc taagtcgcag gtgcaagtgc agtttcaatc      720

agaagccccg ggccccagga gatgaggaag cccaggtgga gaacctcatc accgccaatg      780

caacagagcc ccagaaagca gagaactgaa gtgcagccat caggtggaag cctctggaac      840

ctgaggcggc tgcttgaacc tttggatgca aatgtcgatg cttaagaaaa ccggccactt      900

cagcaacagc cctttcccca ggagaagcca agaacttgtg tgtcccccac cctatcccct      960

ctaacaccat tcctccacct gatgatgcaa ctaacacttg cctccccact gcagcctgcg     1020

gtcctgccca cctcccgtga tgtgtgtgtg tgtgtgtgtg tgtgtgactg tgtgtgtttg     1080

ctaactgtgg tctttgtggc tacttgtttg tggatggtat tgtgtttgtt agtgaactgt     1140

ggactcgctt tcccaggcag gggctgagcc acatggccat ctgctcctcc ctgcccccgt     1200

ggccctccat caccttctgc tcctaggagg ctgcttgttg cccgagacca gccccctccc     1260

ctgatttagg gatgcgtagg gtaagagcac gggcagtggt cttcagtcgt cttgggacct     1320

gggaaggttt gcagcacttt gtcatcattc ttcatggact cctttcactc ctttaacaaa     1380

aaccttgctt ccttatccca cctgatccca gtctgaaggt ctcttagcaa ctggagatac     1440

aaagcaagga gctggtgagc ccagcgttga cgtcaggcag gctatgccct tccgtggtta     1500

atttcttccc aggggcttcc acgaggagtc cccatctgcc ccgccccttc acagagcgcc     1560

cggggattcc aggcccaggg cttctactct gcccctgggg aatgtgtccc ctgcatatct     1620

tctcagcaat aactccatgg gctctgggac cctacccctt ccaaccttcc ctgcttctga     1680

gacttcaatc tacagcccag ctcatccaga tgcagactac agtccctgca attgggtctc     1740

tggcaggcaa tagttgaagg actcctgttc cgttggggcc agcacaccgg gatggatgga     1800

gggagagcag aggcctttgc ttctctgcct acgtcccctt agatgggcag cagaggcaac     1860

tcccgcatcc tttgctctgc ctgtcagtgg tcagagcggt gagcgaggtg ggttggagac     1920

tcagcaggct ccgtgcagcc cttgggaaca gtgagaggtt gaaggtcata acgagagtgg     1980

gaactcaacc cagatcccgc ccctcctgtc ctctgtgttc ccgcggaaac caaccaaacc     2040

gtgcgctgtg acccattgct gttctctgta tcgtgatcta tcctcaacaa caacagaaaa     2100

aaggaataaa atatcctttg tttcctagtg gc                                   2132


<210>  604
<211>  6344
<212>  DNA
<213>  homo sapiens

<400>  604
atgcattaaa ctccaggtat tttcagggag gaatcatgaa gccgctcctg ttaaatcata       60

tccattttat tacgtctctc cttgtggatt acgtagaact ttggaaaatt aaacattaga      120

catcttcata gaaaatcatg tcactgattt ttaaagccag ctcaatttaa cctgccactg      180

attccctaac cagctcttct ctgactgtat cccgagggaa aatgtattga acgcagcaga      240

aggttaaggc agaggagttc ggctagaccg ggtagcagcc aatcagatgg ggagggtcca      300

aggatctgat gcctccaggc gagcagcgcc aagctgagct ggttagtctc cttttattgt      360

ggatgaacac cacgtacatg ccgtaaatgc tccctaggct ggctgcggct acaaggcaga      420

cccgggagct gagaatagag gaatacctgc ccaagcaact cattctgcac agcagccgac      480

aagacagcga ttttcctgtg ctggaatgtg cccatccaaa gacacttgga ttggacttaa      540

tcttaaacct ctggagttca agacctttta aaaagggcta aataaacaat ctctacatgt      600

aaaaggccac tgactcctac ttcctctgta tagagcaact gttgaactca gctgcctgta      660

gggcgtgatt ctcagtcacc agactcagct tggagatctt acaatgatgg caatcaggag      720

acactgaacg gagatgctac atattcctct cttgcagcaa aaggttttag aagcgttcga      780

ccaaacctac aagataaaag atcaccaact cagagccaga taacagtgaa tggaaactca      840

ggaggtgccg tgagtcccat gagttactat cagaggccgt tttccccctc ggcatattct      900

ctcccagcct cactcaactc cagcattgtc atgcagcacg gcacatccct cgattccaca      960

gacacatatc cccagcatgc gcagtctctg gatggcacca ccagcagctc tatccccctg     1020

taccgatcct cagaggaaga gaagagagtg acagtcatca aagccccgca ttacccaggg     1080

atcgggcccg tggatgaatc cggaatcccc acagcaatta gaacgacagt cgaccggccc     1140

aaggactggt acaagacgat gtttaagcaa attcacatgg tgcacaagcc ggatgatgac     1200

acagacatgt ataatactcc ttatacatac aatgcaggtc tgtacaaccc accctacagt     1260

gctcagtcac accctgctgc aaagacccaa acctacagac ctctttccaa aagccactcc     1320

gacaacagcc ccaatgcctt taaggatgcg tcctccccag tgcctccccc acatgttcca     1380

cctccagtcc cgccgcttcg accaagagat cggtcttcaa cagaaaagca tgactgggat     1440

cctccagaca gaaaagtgga cacaagaaaa tttcggtctg agccaaggag tatttttgaa     1500

tatgaacctg gcaagtcatc aattcttcag catgaaagac cagcctcctt gtatcagtcc     1560

tctatagaca gaagcctgga aagacccatg agttctgcaa gcatggccag tgacttcagg     1620

aagcggagga agagcgagcc tgcagtgggt ccaccacggg gcttgggaga tcaaagtgcg     1680

agcaggacta gcccaggccg agtggacctc ccaggatcaa gcaccactct tacaaagtct     1740

ttcactagct cttctccttc ttccccatca agagcaaaag gtggggatga tagcaaaata     1800

tgtccatccc tttgcagtta ctcagggctc aacggcaacc cctccagtga gttagattac     1860

tgtagcactt acagacagca cttggatgtc cctcgggact caccaagagc cattagtttc     1920

aagaacggct ggcaaatggc ccggcaaaac gcagaaatct ggagcagcac ggaagaaacc     1980

gtctctccca aaatcaaatc ccggagctgt gacgatctcc taaacgacga ctgcgatagc     2040

ttcccggacc cgaaagtcaa gtcggaaagc atgggctccc tgttatgtga ggaggactcc     2100

aaggagagct gccccatggc gtgggggtcc ccctacgtcc cggaggttcg cagtaacggc     2160

agatcaagga tcagacacag gtcagcccgc aacgccccgg ggttcctgaa gatgtacaag     2220

aaaatgcacc gcatcaaccg caaggacctg atgaactccg aggtgatctg ctccgtgaag     2280

tccaggattc tgcagtacga gagcgagcag cagcacaagg acctgctgcg cgcctggagc     2340

cagtgctcca cggaggaggt gccccgggac atggtgccca cacgcatctc cgaattcgaa     2400

aagctgatcc agaagtccaa atccatgcca aatttagggg atgacatgct gtctcccgta     2460

accctagaac caccgcaaaa tggcctatgt cccaagaggc ggttttccat tgagtatttg     2520

ctggaggaag aaaatcaaag cggccccccc gctcggggcc ggcgaggctg ccagtctaac     2580

gccctggtgc ccattcacat tgaagtcacc agcgatgagc agccccgagc acacgtggag     2640

ttttccgaca gcgaccagga cggggttgtg tccgaccaca gtgactacat tcacctagag     2700

gggtcatcct tctgcagtga aagtgacttt gatcactttt ccttcacatc ctccgaaagc     2760

ttttacggat ccagccacca ccaccaccat caccaccacc accaccaccg ccacctcatc     2820

agctcctgca aaggcaggtg cccggcctcc tacactcgat ttaccacaat gttaaaacac     2880

gaaagagcca gacacgaaaa caccgaggag cccagaaggc aagaaatgga ccctggcctt     2940

tctaaacttg cttttctagt cagtcctgtg cctttccgga ggaaaaaaaa ttcggctcct     3000

aagaaacaga ctgaaaaggc aaaatgtaaa gcatctgtgt ttgaggctct ggactctgcc     3060

cttaaagaca tctgtgacca aattaaagct gaaaagaaaa gggggagctt gccggacaac     3120

agcatcctgc accgcctcat cagtgagctg ctgccagatg ttcccgagag gaactcatcc     3180

ctgagagcgc tgaggaggag ccccctgcac cagcctctcc acccactgcc tcccgatggt     3240

gctattcatt gtccacccta ccagaatgac tgcgggagaa tgccccgcag tgcctctttc     3300

caagacgtgg acacagccaa cagcagctgc caccaccaag accgtggcgg tgcactccaa     3360

gaccgtgagt cccctagaag ttactcatcc actttgactg acatggggag aagtgcacca     3420

agggaaagaa gaggaactcc agaaaaagag aaattgcctg caaaagctgt ttatgatttt     3480

aaggctcaga catctaagga gttgtcattt aagaaaggag atactgtcta catcctcagg     3540

aaaattgatc aaaattggta tgagggagaa caccacggga gagtgggcat cttcccgatc     3600

tcatacgtag agaaactcac acctcctgag aaagcacagc ctgcaagacc acctccgcca     3660

gcccagcccg gagaaatcgg agaagctata gccaaataca acttcaacgc agacacaaat     3720

gtggagctgt cactgagaaa gggagataga gttattcttc ttaaaagagt tgatcaaaac     3780

tggtatgaag gtaaaatccc aggaaccaac agacaaggca tcttccctgt ttcctatgtg     3840

gaggtcgtca agaagaacac aaaaggtgct gaggactacc ctgaccctcc aataccccac     3900

agctattcta gtgataggat tcacagcttg agctcaaata agccacagcg tcctgtgttt     3960

actcatgaaa atattcaagg tgggggggaa ccgtttcagg ctctgtataa ctatactccc     4020

aggaatgaag atgagctgga gctcagagaa agtgatgtca ttgatgtcat ggaaaagtgt     4080

gatgacggct ggtttgtggg gacctcaaga agaaccaaat tctttggtac tttccccgga     4140

aactacgtca agaggctgtg aattgcgctc cctccttctg tagaggccgc ctgccagcca     4200

tgcacctgcg tcaacgcgcc tgaaacaccc cgcgggcctc ccgttgtcat gccttacggt     4260

ttccaatgcg ccgtcaccat ctccacctgc caccaaacca ccagcagagt agccgccgct     4320

gctgtgagcc tggggacgac atggcaggct ggtccccctc cgtgaaagtg tggattccta     4380

cttcctgctc taagctttga cacgtcaaaa tgtgggatca gaaagaaaaa aatcatgata     4440

tttaaaaatg gtcaaatatt tgaggcaaaa aaaaaaaaaa aaagtgtctc caggaggctg     4500

tccagcctcg tggctccatt tcaacatctc cccccaggcg atgttctccc ccaagacgac     4560

cagaaaattg tttattgggg aatgctgtgg tttgcatttt catattcttc gcttggcagt     4620

gtgtattctt ttcacaagtt tgcctagtgt cttggtttac acaatatgac aactgtaact     4680

gtactttagc tattgtttgc ctgcacatac atgttgtaat atgcacagtg attacaacct     4740

ttaaagcaag aggaggcgag ttaatttgga tgagtgtgat tttgctgatt gaatgtgagt     4800

tttcaaatag gagtcttttt ctgcaatttg tttgcatttt ttagaagtgc aaacagtaag     4860

taaataaaag ccttcggtaa taatcatgac aatacaagag gctgagctag gctacagggg     4920

aaaactattg tgttgtaaag ttgcatcgct attttatatt aaaatgtaat gatcagcatc     4980

atgaacaatg agctcttagt gttttattta tctgaaaaaa tgtaagtaaa agcagtgtta     5040

gtgagaggtg caaagaatta ttctaacaga cacctgaaag tatctgtaag caatactagt     5100

aggtaagatt tcactgtgtg tacacataca catttgagat tgtatgagaa catataatcc     5160

atatgatatg ttgtacattt tatggaaatg taatagaatc tcacacatta ttttatagaa     5220

atagagtaca gaagcatcac aagtattaaa gttggtttta gcaaggatta ggattactac     5280

aattattttt actataataa ttatttttct tctatggaac tcagaatcct ggctacattt     5340

gaggacagga atatgttgag cctgattttc ctggtgtgtg taaaatattt cctaggaata     5400

aattaggcac tttttagaag caatgttaaa tcattcaggt tttattttct gccctgaagc     5460

agaaatttaa aaaatgatat tgggacctgg aaggtttaat atggttcaca gtgcctgaat     5520

tacacctgct ccgaaaacta gctttgtatt tcttatgact ttgcataaga actgttcatc     5580

tttggatctt gagcacctta cagataaaac tttttatggc atctctttca tggacagtga     5640

tattgatctt ttcacaatgt acgtagcctc tagaattttg tacatatgtt tgctcttttt     5700

ttgtacagac tagttgttga gaaaacaggg gcgtttccta atttggtctt tatcctgcga     5760

caacactttc agcagactag cctctcctta tctcacagat cacaagcacc cctagatagt     5820

gtgattctgt cagatagcat ttatgcaaaa atctatgaag ttaaaagatc gtagaagcca     5880

aatgaaatgt acatatctac tgactgatga caagggaatt tcattaggaa gaaggtaaag     5940

aaacatcgtt gagtagccta ccttgatttc tgtcaagttc ataaccagct tcatatttta     6000

aaggcttcag gtttgaaatt aagtcaactg catgcagctt tgctgataaa tgaataattc     6060

tctttgatgc catttatgag aaaagacttc aatatctgtt gcctgtcata tttaagaaaa     6120

attactgttt ctactctctg tatctgattt taaaagaaaa aactattcat acctggcttc     6180

caggtaattg actttgaatt cttacaagca aaggtcattg tgtttttctt gaatagacat     6240

ctaataaatt ttgcttggaa gtatacttca gtttttcttc ttgacattta tctttataaa     6300

aattgtgtat tttattccaa cttgttaaac taagagaaaa tgca                      6344


<210>  605
<211>  5313
<212>  DNA
<213>  homo sapiens

<400>  605
gcggccgccg gcgaggcgag gcggcccgcg ccctgcctgt caggccaccg gcccggcccg       60

cgggctgccc ccgatgcgga ggcgctgtcg ccggggccat gcagcaggcg ccgcagcctt      120

acgagttctt cagcgaggag aacagtccga aatggcgggg actgttggtc tcggccctgc      180

ggaaggttca ggaacaagtg catcccactc tctcagctaa tgaagagtct ctctattata      240

ttgaagagct gatttttcag ctgcttaata aattatgcat ggcccagcca aggactgttc      300

aagatgtaga ggagcgagtt cagaagacct ttcctcaccc aattgataaa tgggccattg      360

ctgatgcaca atctgctata gaaaaacgaa aacgaagaaa tcctctttta ctgcctgtgg      420

acaaaatcca tccttcgttg aaggaagtat tagggtacaa agtggactac catgtatccc      480

tatatattgt ggctgtacta gagtatatct cagctgatat tttaaaattg gctggtaatt      540

atgtttttaa tatccggcat tatgaaatat ctcagcagga cattaaagtg tcaatgtgtg      600

cggataaggt tttgatggac atgtttgatc aggatgacat aggtttggtt tctctctgtg      660

aagatgaacc tagttcttct ggtgaattaa actactatga tcttgtcaga actgaaatcg      720

cagaagaaag acagtatcta cgggaattaa atatgatcat aaaagtgttt cgagaagcct      780

ttctttctga tagaaagctg tttaaacctt ctgatatcga aaagattttt agtaacattt      840

cagatataca tgaattgact gtgaaacttt taggtttgat tgaagacaca gttgaaatga      900

ctgatgaaag cagtcctcat cccttagctg gcagctgttt tgaagatttg gcagaagagc      960

aagcatttga tccttatgaa acattatcac aggacattct ttcaccagag tttcatgaac     1020

atttcaataa attgatggcc agacctgcag ttgctctaca ctttcagtcc attgctgatg     1080

gttttaaaga ggcagttcgt tatgtccttc cacgtcttat gctggtgcca gtgtatcact     1140

gttggcacta ctttgagtta ctaaagcaat tgaaagcatg tagtgaagaa caagaagaca     1200

gagaatgttt gaaccaagct attactgctc tcatgaatct ccaaggtagc atggaccgaa     1260

tttacaagca gtattcacct agacgtcgac ctggagatcc tgtttgccct ttttatagtc     1320

accaattaag aagcaaacac ctggctatca aaaaaatgaa tgaaattcag aaaaatatcg     1380

atggatggga aggcaaagat attggacagt gttgtaatga attcattatg gagggaccat     1440

tgacaagaat cggtgccaaa catgaacggc atatttttct gtttgatggc ttaatgatca     1500

gttgtaaacc taatcatggc cagactcggc ttccaggtta cagtagtgca gaatacaggt     1560

taaaagaaaa atttgtcatg aggaaaatac aaatttgtga taaagaagat acttgtgagc     1620

acaagcatgc atttgaatta gtatccaaag atgagaacag cataatattt gctgctaagt     1680

ctgctgaaga aaaaaacaac tggatggcag cccttatttc tcttcattat cgtagtactc     1740

tagatcgaat gttagattca gtattattga aagaagaaaa tgagcaacca ctgagattac     1800

caagtcctga agtatatcgt tttgtagtaa aagactctga ggaaaacatt gtttttgaag     1860

acaacttgca aagtagaagt ggcatcccca ttattaaagg aggaactgta gtgaaattaa     1920

ttgaaaggtt aacatatcat atgtatgcag atcccaattt tgttcgtact tttcttacca     1980

catatcgttc attttgtaaa ccacaggaat tgctgagctt actgattgaa cggtttgaaa     2040

ttccagagcc agaacctact gacgcagaca aattggcaat agagaaaggc gagcagccaa     2100

tcagtgcaga ccttaaaaga tttcgcaagg aatatgtcca accagtacaa cttaggatct     2160

taaatgtatt tcggcattgg gttgaacatc atttttatga ctttgaaaga gacttggaat     2220

tgcttgaaag actagaatcc ttcatttcaa gtgtaagagg gaaagctatg aaaaaatggg     2280

tagagtcaat tgctaagatc atcaggagga agaagcaagc tcaggcaaac ggagtaagcc     2340

ataatattac ctttgaaagt ccacctccac caattgaatg gcatatcagc aaaccaggac     2400

agtttgaaac atttgatctc atgacacttc atccaataga aattgcacgt cagctgacac     2460

ttttggagtc tgatctttac aggaaagttc aaccgtctga acttgtaggg agtgtgtgga     2520

ccaaagaaga taaagaaata aattctccaa atttattaaa aatgattcgc cataccacaa     2580

atctcaccct ctggtttgaa aaatgcattg tggaagcaga aaattttgaa gaacgggtgg     2640

cagtactaag tagaattata gaaattctgc aagtttttca agatttgaat aatttcaatg     2700

gcgtattgga gatagtcagt gcagtaaatt cagtgtcagt atacagacta gaccatacct     2760

ttgaggcact gcaggaaagg aaaaggaaaa ttttggacga agctgtggaa ttaagtcaag     2820

atcactttaa aaaataccta gtaaaactta agtcaatcaa tccaccttgt gtgccttttt     2880

ttggaatata tttaacaaat attctgaaga ccgaagaagg gaataatgat tttttaaaaa     2940

agaaagggaa agatttaatc aatttcagta agaggaggaa agtagctgaa attactggag     3000

aaattcagca gtatcagaat cagccttact gtttacggat agaaccagat atgaggagat     3060

tctttgaaaa ccttaacccc atgggaagtg catctgaaaa agagtttaca gattatttgt     3120

tcaacaagtc actagaaatt gaacctcgaa actgcaaaca gccacctcga tttcctagga     3180

aatcaacttt ttccttaaaa tctcctggaa taaggcctaa cacaggccga catggctcta     3240

cctcaggtac tttacgaggt cacccaacac cattagaaag agaaccatgt aaaataagct     3300

ttagtcggat tgctgaaact gagctggaat caacagtgtc agcaccaacc tctccaaata     3360

caccatctac tccaccagta tctgcttctt cagaccttag tgtattttta gatgtggatc     3420

tcaacagctc ctgtggcagc aatagcatct ttgctccagt gcttttgcca cattcaaagt     3480

ctttctttag ttcatgtggt agtttacata aactaagtga agagcccctg attcctcctc     3540

ctcttcctcc tcgaaaaaag tttgatcatg atgcttcaaa ttccaaggga aatatgaaat     3600

ctgatgatga tcctcctgct attccaccga gacagcctcc tcctccaaag gtaaaaccca     3660

gagttcctgt tcctactggt gcatttgatg ggcctctgca tagtccacct ccgccaccac     3720

caagagatcc tcttcctgat acccctccac cagttcccct tcggcctcca gaacacttta     3780

taaactgtcc atttaatctt cagccacctc cactggggca tcttcacaga gattcagact     3840

ggctcagaga cattagtacg tgtccaaatt cgccaagcac tcctcctagc acaccctctc     3900

caagggtacc gcgtcgatgc tatgtgctca gttctagtca gaataatctt gctcatcctc     3960

cagctccccc tgttccacca aggcagaatt caagccctca tctgccaaaa ctgccaccaa     4020

agacttacaa acgggagctt tcgcaccccc cattgtacag actgcctttg ctagaaaatg     4080

cagaaactcc ccaatgacct tagccatatg tagtcattga cactggaatg gtatttgtaa     4140

agtttttttt ttaatttatt caaaaaaaga catagtattt tagtactttt tacaaataat     4200

gctcttacaa aaatgctact gatcaaataa gcttttaaga attggaaaaa taaaaataca     4260

aaagtccttc accattatcc tcaggtgatc agtagcattg ccttgtcttg gatcctcagt     4320

gctgccaaaa ggccagtata aagaatttat atttgcactg taaactctgc aaaaatatgg     4380

tttaaagtga catgattgca ctgaaaaggg atagtgcttt tgtgaaattt ttcaaatttg     4440

agtaatagat gcctttttaa ggcagtgaat ttacacaaat atgggagggg tatatggtgt     4500

tactgatttt taaacctctt tgaccatctt ctagttttta cttctagttt ttacatctag     4560

gagaattgtg aataacacca actgttctta aactctttaa tgccatgtct taaatgccgg     4620

tatttgctgc tgaagacaaa aatgaaaagt aggatgaaaa taatagaatg gcactgtaag     4680

tgtttattat tttgtcaaaa tgtaaacaaa gactacataa cccaatgatg gagggaaaaa     4740

gggcatgtat ctcattcaga tgtgcctttt gtttttgcag actatgacgt ctttagctaa     4800

tgaattgcct attgttatgg aaaacagtta atatgccatg tatgtacagt tttgtttata     4860

ttgtatattt aaagatactg ctaataacct atataaattt aagtgacttg aggcctataa     4920

tacaatctgc tactttacta attcataaat tcaaaaaaaa ttctatggca taggaaccaa     4980

ctgccttgcc ttcaagacct agtaactttc tctataaatc tcgtgttaac tgaaattttt     5040

tttaaatata ttttttagat tggtaatatt taaaccagca aatacttaaa gctttattaa     5100

acattttaat cagataagtg agtaaagctt ttatttgcca tttggatgcc ttcgttcaaa     5160

gtgatagagt gttttgctga tagtgctgta gcagcagttg taaagtagcc aaaagccacg     5220

ttgtttattt actggtttgt ggccttttac tgtgctttgt atcagagttc ttaacaagat     5280

taataaatca ccccagtctt aatttttaaa aga                                  5313


<210>  606
<211>  2945
<212>  DNA
<213>  homo sapiens

<400>  606
acactccagc cgctgagagc cccctttggc acttggcagc acgcggcggc gggctcctcg       60

gctcaacttc gaggagtctc cgcgacgcaa cttttgggga cgctttgcat ttaagagaga      120

acgaccgagg aggaggagcg ctctgcccgg ccgccgctac ctgcggggag ctcaccagca      180

aacgccactg cagacgaagg acccaaagaa cgtaaagggc aaactgccgc cgcggggagg      240

gggcaccgcc gagaagttag agtgtcccag agacaacctg ctcgagcgct cggccggaga      300

cactaaggcg gcccggggcg cggcgtggcc ctgggctggt cccccagccc cctcctccgg      360

ggcgggagcg acgccggggc gcgacgagcc ccggccggcc gagcgggtct ccgcgggcag      420

ccaacattga tttcctccgg gccgagggcg agggcccggg aggcggcggg ctgcagccgc      480

ggcagggcga gagcatgtcc aagccggtgg accacgtcaa gcggcccatg aacgccttca      540

tggtgtggtc gcgggctcag cggcgcaaga tggcccagga gaaccccaag atgcacaact      600

cggagatcag caagcgcttg ggcgccgagt ggaaactgct cacagagtcg gagaagcggc      660

cgttcatcga cgaggccaag cgtctacgcg ccatgcacat gaaggagcac cccgactaca      720

agtaccggcc gcggcgcaag cccaagacgc tgctcaagaa ggacaagttc gccttcccgg      780

tgccctacgg cctgggcggc gtggcggacg ccgagcaccc tgcgctcaag gcgggcgccg      840

ggctgcacgc gggggcgggc ggcggcctgg tgcctgagtc gctgctcgcc aatcccgaga      900

aggcggccgc ggccgccgcc gctgccgccg cacgcgtctt cttcccgcag tcggccgctg      960

ccgccgccgc tgccgccgcc gccgccgccg cgggcagccc ctactcgctg ctcgacctgg     1020

gctccaaaat ggcagagatc tcgtcgtcct cgtccggcct cccgtacgcg tcgtcgctgg     1080

gctacccgac cgcgggcgcg ggcgccttcc acggcgcggc ggcggcggct gcagcggcgg     1140

ccgccgccgc cggggggcac acgcactcgc accccagccc gggcaacccg ggctacatga     1200

tcccgtgcaa ctgcagcgcg tggcccagcc ccgggctgca gccgccgctc gcctacatcc     1260

tgctgccggg catgggcaag ccccagctgg acccctaccc cgcggcctac gctgccgcgc     1320

tatgaccccg cggggccgcc tcgcgaggac cggtgtgcac acgtgtacat atgtataggt     1380

acgagcgctg cggcctcccc gtgcgccctc ccgcgaccgg gggcccggtt tgtatgtaca     1440

tagaatgtat aggtgccagg tagaggcaga gaggccaggc ggggcaggag tggccaagcg     1500

cgcaagggcg cgggcgagca ggcctgtgaa ttcgcaggat catttcagac ccgcacttcg     1560

gcagccaact cgaaagcagg cggttgtgtg cggcagcagt tggcgtttgc tttgcacttc     1620

ggaacctgtt gcgttttgac ccacggaggt ggaggagtaa ctttttgaca tgttggcctt     1680

tccagttttg ttggaagttt catggtcggt tttgtttttg tttctcattc ttcttcctcg     1740

cccctcagcc ccccaacccc caaccccctc ccggtccgtg ttgcatgcac gctgttcaaa     1800

tgtgaggtct gaaatggctg gcacacggga aaagctgctt gtgtcattcg tttctgggag     1860

tgggatggct ctgagcagcc tcgcctccct gtttgtacta tttgaacttt gcagatctct     1920

gttctctcaa gcagaactcc caaccagatc cattcttgac cagtgaccgg ctcgaatctg     1980

gccttttgtg tgagatgatc acggtttctt ttgtttatca cgccatttgc aaatcagagc     2040

aagagctctt tctcaagggc aagaaacgca aacaagaaat atttgtgaga tgaaagttgt     2100

caattggatt ttcttcctaa acaaacaaca acaacaaact actagaagtc tccctgagtc     2160

cactcgcttg gatttctgac acagtttaca aaaaaggaaa aaggcactgc tcctattttc     2220

ccttatggct gagttcacct taagattgta aatgtgtata tgtcagtgaa aacattgagg     2280

cttggaaaat gtgttatttt cgttgcccta agtttgagtc gactttagac tcaaaaacat     2340

tttgagcgaa tatcaaagtt aacttttaaa aattgcgaaa ctatttcaga atcgcaattt     2400

tatcgaagat taaatcagac ttttttgtct ggtaattata tatttattat ttagcaaaac     2460

tgaagaaaaa aagcacagaa ttgtttcaac agatgtctct cattttcagc tagcatttct     2520

ctcccaagtt gagctggttt aatgtgtttt ggatttccct cctcaattgg cttatttttt     2580

agatcacctg caattcattt gcaaattgca ataaaacaca ttttagaaaa aaggaacctt     2640

caattattag ctttgtttct ttttaaatgt atatattttg actaatgttt gtgaatgaag     2700

ttggctaaca tgtatttagt ttcattttgg ctttatgtaa tataaagttt ttaaaatttt     2760

aaatatggtt ttaaccttta tgtgtaaatg attttctagt gtgaccttct aatttaatat     2820

tagacgtcta aggtatatct gtaaattaga atccgactat cactctgttc attttttttg     2880

aacaaagagt ttaaataaag cctgaaccag ggaaaagaaa aaaaaaaaaa aaaaaaaaaa     2940

aaaaa                                                                 2945


<210>  607
<211>  6046
<212>  DNA
<213>  homo sapiens

<400>  607
aggccccacc cgctggtggc ccggtccgcg tgtgcgccga ctctcgcact ctcctcgctc       60

cgggcgccca gactctgaga gagagcgacg gccatcatag aacagcgaag gcagtcgatc      120

ggcctgcggt ccgcttcggc attcgcaggc cgcaggcggg aggctagagc ccccaggcgc      180

acctcgcccc aaccgcccgc ggctcgggca gctctgcaga gacgtcgtgg cggcagggcc      240

agcacccatt ggtccgccac agccctccgc cctccccctc gccacgctta ttggccggag      300

cggcggcgct cgccgggtag gcggtggcgg cgtccctccc ttgcgccggc cctcaagagg      360

cgacgaggaa gcggccgcct ccctgcgccc cgcccctccg gctagctcgc tggctcccgg      420

ctcctcccga cgtctcctac ctcctcacgg ctcttcccgg cgctctcctg gctcccttct      480

gccccagctc cgtctcggcg gcggcgggca gttgcagtgg tgcagaatgg ctgacctcag      540

tcttgcagat gcattaacag aaccatctcc agacattgag ggagagataa agcgggactt      600

cattgccaca ctagaggcag aggcctttga tgatgttgtg ggagaaactg ttggaaaaac      660

agactatatt cctctcctgg atgttgatga gaaaaccggg aactcagagt caaagaagaa      720

accgtgctca gaaactagcc agattgaaga tactccatct tctaaaccaa cactcctagc      780

caatggtggt catggagtag aagggagcga tactacaggg tctccaactg aattccttga      840

agagaaaatg gcctaccagg aatacccaaa tagccagaac tggccagaag ataccaactt      900

ttgtttccaa cctgagcaag tggtcgatcc tatccagact gatcccttta agatgtacca      960

tgatgatgac ctggcagatt tggtctttcc ctccagtgcg acagctgata cttcaatatt     1020

tgcaggacaa aatgatccct tgaaagacag ttacggtatg tctccctgca acacagctgt     1080

tgtacctcag gggtggtctg tggaagcctt aaactctcca cactcagagt cctttgtttc     1140

cccagaggct gttgcagaac ctcctcagcc aacggcagtt cccttagagc tagccaagga     1200

gatagaaatg gcatcagaag agaggccacc agcacaagca ttggaaataa tgatgggact     1260

gaagactact gacatggcac catctaaaga aacagagatg gccctcgcca aggacatggc     1320

actagctaca aaaaccgagg tggcattggc taaagatatg gaatcaccca ccaaattaga     1380

tgtgacactg gccaaggaca tgcagccatc catggaatca gatatggccc tagtcaagga     1440

catggaacta cccacagaaa aagaagtggc cctggttaag gatgtcagat ggcccacaga     1500

aacagatgta tcttcagcca agaatgtggt actgcccaca gaaacagagg tagccccagc     1560

caaggatgtg acactgttga aagaaacaga gagggcatct cctataaaaa tggacttagc     1620

cccttccaag gacatgggac cacccaaaga aaacaagaaa gaaacagaga gggcatctcc     1680

tataaaaatg gacttggctc cttccaagga catgggacca cccaaagaaa acaagatagt     1740

cccagccaag gatttggtat tactctcaga aatagaggtg gcacaggcta atgacattat     1800

atcatccaca gaaatatcct ctgctgagaa ggtggctttg tcctcagaaa cagaggtagc     1860

cctggccagg gacatgacac tgcccccgga aaccaacgtg atcttgacca aggataaagc     1920

actaccttta gaagcagagg tggccccagt caaggacatg gctcaactcc cagaaacaga     1980

aatagccccg gccaaggatg tggctccgtc cacagtaaaa gaagtgggct tgttgaagga     2040

catgtctcca ctatcagaaa cagaaatggc tctgggcaag gatgtgactc cacctccaga     2100

aacagaagta gttctcatca agaacgtatg tctgcctcca gaaatggagg tggccctgac     2160

tgaggatcag gtcccagccc tcaaaacaga agcacccctg gctaaggatg gggttctgac     2220

cctggccaac aatgtgactc cagccaaaga tgttccacca ctctcagaaa cagaggcaac     2280

accagttcca attaaagaca tggaaattgc acaaacacaa aaaggaataa gtgaggattc     2340

ccatttagaa tctctgcagg atgtggggca gtcagctgca cctactttca tgatttcacc     2400

agaaaccgtc acaggaacgg ggaaaaagtg cagcttgccg gccgaggagg attctgtgtt     2460

agaaaaacta ggggaaagga aaccatgcaa cagtcaacct tctgagcttt cttcagagac     2520

ctcaggaata gccaggccag aagaaggaag gcctgtggtg agtgggacag gaaatgacat     2580

caccacccca ccgaacaagg agctcccacc aagcccagag aagaaaacaa agcctttggc     2640

caccactcaa cctgcaaaga cttcaacatc gaaagccaaa acacagccca cttctctccc     2700

taagcagcca gctcccacca ccattggtgg gttgaataaa aaacccatga gccttgcttc     2760

aggcttagtg ccagctgccc cacccaaacg ccctgccgtc gcctctgcca ggccttccat     2820

cttaccttca aaagacgtga agccaaagcc cattgcagat gcaaaggctc ctgagaagcg     2880

ggcctcacca tccaagccag cttctgcccc agcctccaga tctgggtcca agagcactca     2940

gactgttgca aaaaccacaa cagctgctgc tgttgcctca actggcccaa gcagtaggag     3000

cccctccacg ctcctgccca agaagcccac tgccattaag actgagggaa aacctgcaga     3060

agtcaagaag atgactgcaa agtctgtacc agctgacttg agtcgcccaa agagcacctc     3120

caccagttcc atgaagaaaa ccaccactct cagtgggaca gcccccgctg caggggtggt     3180

tcccagccga gtcaaggcca cacccatgcc ctcccggccc tccacaactc ctttcataga     3240

caagaagccc acctcggcca aacccagctc caccaccccc cggctcagcc gcctggccac     3300

caatacttct gctcctgatc tgaagaatgt ccgctccaag gttggctcca cggaaaacat     3360

caagcatcag cctggaggag gccgggccaa agtagagaaa aaaacagagg cagctgctac     3420

aacccgaaag cctgaatcta atgcagtcac taaaacagcc ggcccaattg caagtgcaca     3480

gaaacaacct gcggggaaag tccagatagt ctccaaaaaa gtgagctaca gccatattca     3540

gtccaagtgt ggttccaagg acaatattaa gcatgtccct ggaggtggta atgttcagat     3600

tcagaacaag aaagtggaca tctctaaggt ctcctccaag tgtgggtcta aggctaacat     3660

caagcacaag cctggtggag gagatgtcaa gattgaaagt cagaagttga acttcaagga     3720

gaaggcccag gccaaggtgg gatccctcga taatgtgggc cacctacctg caggaggtgc     3780

tgtgaagatt gagacctaca ggctgacgtt ccgggcaaat gccagggccc gcaccgacca     3840

cggggccgac attgtctccc gccccccaca cttccctggc ggccccaact cgggctcccg     3900

ggtccttggc cccctttccc gggctgtcca ctagaccagt gagcgcttgg gcgccgtgct     3960

gggcagcccg ctaggctcgc cttccctcct gctttgcgtg cccggggcag cagcagccct     4020

gccccacacc tcctctcact ccccagcctg ggcccatctc cctgctttgg tcttgcccca     4080

tcactgcgcc actgctccgt ggaggaggtt gggagggggt tggggtggtt gaggctaagt     4140

tgggatctag gagaggagaa ccagattcta tcctcatctt tttttggttc tttggtccaa     4200

acccaaaaga aactgacatg ccctcccttc tccctggatc tacctggagg gaagagtgga     4260

ggtggattcc gagtggtgac aggacgctga ccgtggagct taagccactg cctctccctc     4320

tggtcccaca aatgggcgcc cccccctccc catgcaggtg gtgtcgggcc cttcttgctg     4380

ccctgcccca agttgggggt cagtgctgcc tgtccccatg cttaacatac ccgcctagct     4440

gctgtcacat ttttcttgtt ttgtcctttt atttttttct aataacctaa aaactggcaa     4500

aatagttctg caggttgaag ccatgtctac atgaaagtcc tcagtaagtg ttagagggaa     4560

cagggcggag atatccttat gccacccccg ctggaggatg tgggcagctt agggccctgg     4620

aggcggtgcg gcagggaaga ggggtgcaga ggctgtggct ggtgagccgg tcaggcacac     4680

aaggggccct tggagcgtgg actggttggt tttgccattt tgttgtgtgt atgctgcttt     4740

tcttttctaa ccaagaggct ggttttggca tctctgtccc attccctggg atctggtggt     4800

cagccctagg ataaaaagcc agggctggag aacaagaaag ggccaggaga tggaattcct     4860

tcaggccggc acccacaccc taggacatgt aagccctcat gtccaaggga gcctcatgca     4920

gatagtagga aatcaggtct ggaaatttaa aaataaaagg catgagacta aggctatctg     4980

cttcccttat gccctgactg gagaggggag ggaggagagg caaggcccac agagggcatc     5040

ccagctaggc cttgggatgg ctgcagtgag gagaaatccc gggaactgta ttgacacaaa     5100

gattcttatt gcacttgtat tttttgtatt aaagtttgca tggtttctaa taaaggattc     5160

aaacataagt ttgtagtgaa atggcctggg agattccaag ggcttctctg gagggggatt     5220

ggctgcagtg tagatttgcc tctgaggagg ctgccccaga cttggcctcc tcatgccccc     5280

tcctgacctc tgcccttctc tggtcctggc atccctggag aaggtagggg tcttgaccta     5340

agtttagatt tgatctccat gtgcagggag gctgtcctgg gcctgacagg tcctccccct     5400

ttctgaggta gcagtgcctt gtggaggttt gacaccatgt ccctagctcc ccaagcacac     5460

accaggaaac tgcaggggct cacggaggaa gtgctgcctg ggccaggggg accagctttc     5520

ctccgtagag accatgtgca gaacacttct gctgtgccaa gaacatgagg gagccagtgt     5580

tttgtcagca ggaagaaagg gcctgctggg atgaaagtgg gaaggaaaca gggttgcgta     5640

gtcaggagac acctcagggg caacagcaca ggcccagagt acctgctgcc tccactgcgt     5700

ctgtcctggg gtcatgagga tgctgaggtt gacgacaggt tccaggtcct ttcactcctt     5760

tggccaaagg ttgggggtag gtggcccaag tggcgtgctc tctaggtaga caacaggagt     5820

ggtcagagtt ccctcaaagg atcctccact ccagagcacc tgagaaggcc gggaccagag     5880

gccctgtgtg atgtgtactc cgcagctgtt tggggtggga catttctgta cttctcgatt     5940

tgcttatggc tcagccatta cctgtgtcag tccatgattc tgttgtaaca gttttaagag     6000

taaataaata aagctgcctg atgtcccatc acgcagaaaa aaaaaa                    6046


<210>  608
<211>  3224
<212>  DNA
<213>  homo sapiens

<400>  608
aggccccacc cgctggtggc ccggtccgcg tgtgcgccga ctctcgcact ctcctcgctc       60

cgggcgccca gactctgaga gagagcgacg gccatcatag aacagcgaag gcagtcgatc      120

ggcctgcggt ccgcttcggc attcgcaggc cgcaggcggg aggctagagc ccccaggcgc      180

acctcgcccc aaccgcccgc ggctcgggca gctctgcaga gacgtcgtgg cggcagggcc      240

agcacccatt ggtccgccac agccctccgc cctccccctc gccacgctta ttggccggag      300

cggcggcgct cgccgggtag gcggtggcgg cgtccctccc ttgcgccggc cctcaagagg      360

cgacgaggaa gcggccgcct ccctgcgccc cgcccctccg gctagctcgc tggctcccgg      420

ctcctcccga cgtctcctac ctcctcacgg ctcttcccgg cgctctcctg gctcccttct      480

gccccagctc cgtctcggcg gcggcgggca gttgcagtgg tgcagaatgg ctgacctcag      540

tcttgcagat gcattaacag aaccatctcc agacattgag ggagagataa agcgggactt      600

cattgccaca ctagaggcag aggcctttga tgatgttgtg ggagaaactg ttggaaaaac      660

agactatatt cctctcctgg atgttgatga gaaaaccggg aactcagagt caaagaagaa      720

accgtgctca gaaactagcc agattgaaga tactccatct tctaaaccaa cactcctagc      780

caatggtggt catggagtag aagggagcga tactacagaa gcctagcgtg tctctcaaca      840

ctggggctgc tgcaacacca gaccagtgat ctttcctaag catcgttata cttctaaaac      900

cttcagcatt ttgcagagct ttgcttttca ttcctggaca tgatgtagaa gaaactgagg      960

gtagttcttc ggggcctatt tctgctgatg cctgagcaaa caacctgctt cctcttgtgc     1020

tctgcagggt ttgatggagc ctcatttccc tttgtgaaca caaagtgcaa aatgaattct     1080

ttttaatttt agtaattttt acaaaggtta tctaatgtct tttatttctt gttttcttta     1140

tgattttatc atttgattca ttctcacatt tttttccttt aaatattttt agttgacctt     1200

tttcctttgg ttttcaaatg ttcaacatga atcagaatag tgtaacacca aatgagaaca     1260

tgtgttttca taaaggggtt gaggccacca gtactgcagc gaatttcctt ttcttctccc     1320

tcctccttcc ttctctgagc ttgcttttag ggaaggttaa tcttacaggc tacctatgtt     1380

tctctccacc ttactaaaat ctaaataatg atagatattt taagttttta aattgagtag     1440

ttctgagtaa tcctagaata tttttccaaa ttaaataatc ctttattatt tgcaagttgg     1500

gccaaatttt tttttttttg gagacggact cttaacaatc taagattgtt tcaacaggac     1560

tttcttattc ccattcctaa ttttttcaaa ctaattgctt aaatctagaa ccagttgaga     1620

ttagtactgt acaatggtat gctttgattg tatttataga aatataacat aaaacatgga     1680

ccatgttttg aaatcttaga ggaattctgg tttaaaatct gaaatacttt aaagttttct     1740

atccttttac tgattatgca gcttcttata acccccaagg tacagattat ttcagcttaa     1800

aagaaataat tggcaccatg ttctgagaaa gattttgaga tatacattgt tttttgtttt     1860

tgagacaggg tctcactctt gcctaggctg gagtgcggtg gcgcgatctt ggcttactgc     1920

accctctgcc tcccaggttc aagtggttct cctgcctcag cctcccaagt agctgggatt     1980

ataggtgtgc gccaccacac cagctaattt ttgtattttt agtagagacg gggttttact     2040

ttgttggcca ggctggtctc gaactcctga tctcaagtga tccacccgcc ttggccaccc     2100

aaagtgctgg gattacaggt gtgagacact gtgcctggcc agatatacat tgttttagat     2160

cccctgatac agaactactt ttgagatggt aagattagaa tatcatgaaa gtttaaactg     2220

aatccttgca gcgacttccg gaatttagga agcattccct cttctacagg ggtctggtca     2280

caagggctgg attctctgac aaaaatttct tctatggatt ctggacagaa gacacttgag     2340

ggtgatatgt tttaaaggaa agaggttatg cttatcttct tagcagttga taaaatatta     2400

aaactctctt gccatagaga atacaccatc aaagaaaaca caaccctttc cctttggtgt     2460

acagttattt attaagttga ttttggggtt tctttcgcca gggatctttt caaaactggt     2520

agtagttatt tttaaaaatc atgtttgaca tctttctatt gctcgtaacc agtccctgta     2580

gctgtctaag ttatgggtgg agaagcctgg gtatgacttt ccgttgtgta cactcacact     2640

tcatgattga catttattta ttcttttatt tccatttggt tatgcttatt tttgtttgaa     2700

atttgttttt ttcaaatatg tttccttttt gaacttacag aattgttgaa attttctact     2760

aacagccagc taaaatttgg tatatgttag ctctatctgt ttcacttgga cgtttcattt     2820

tgaaagaaag aaattttatg tttcacatat agttttatac aaagtagcca gtcccataat     2880

gaaatgctgt attgccatag tggtcacacc caagtggtcc agtatctcaa tggtgaggca     2940

gccagactgg tcagggctgc tttgttgaaa tgtgatgatt ttcatatgcc ttctttctct     3000

ttctctctct cttttttttt ccttttttgg cccaatgttg aagatgtaga actttgtttt     3060

taaataatgt ttttataatt tcattcgtat acctaagttt gtattttttg tgactttgga     3120

cttcaacagt ttgtatattg ggacttctaa tgtgattact gtactaaata aattccacta     3180

ataaacatct tacattaaca ccttaaaaaa aaaaaaaaaa aaaa                      3224


<210>  609
<211>  7334
<212>  DNA
<213>  homo sapiens

<400>  609
gctcactcgc tcaactcggc gccgccgcgg ccccacgctc cgggcccgtc ctcgaggcgc       60

gcggcgcggg gcgcgggcgc cggggcctga ggcggcgggc gacgcccggg ggcctgacgg      120

ccggccccgc gccatggtgt gagcgccgcc gcccgtgcac gctccgtccg ccctccgcgc      180

ggcccggccg gcagagagcc ccgagcggcc cgagagcgca gccgagcccg ccgccgccgc      240

ccgcggcccc gcgaggagag taccgggccg gctcggctgc cgcgcgagga gcgcggtcgg      300

cggcctggtc tgcggctgag atacacagag cgacagagac atttattgtt atttgttttt      360

tggtggcaaa aagggaaaat ggcgaacgac tcccctgcaa aaagtctggt ggacatcgac      420

ctctcctccc tgcgggatcc tgctgggatt tttgagctgg tggaagtggt tggaaatggc      480

acctatggac aagtctataa gggtcgacat gttaaaacgg gtcagttggc agccatcaaa      540

gttatggatg tcactgagga tgaagaggaa gaaatcaaac tggagataaa tatgctaaag      600

aaatactctc atcacagaaa cattgcaaca tattatggtg ctttcatcaa aaagagccct      660

ccaggacatg atgaccaact ctggcttgtt atggagttct gtggggctgg gtccattaca      720

gaccttgtga agaacaccaa agggaacaca ctcaaagaag actggatcgc ttacatctcc      780

agagaaatcc tgaggggact ggcacatctt cacattcatc atgtgattca ccgggatatc      840

aagggccaga atgtgttgct gactgagaat gcagaggtga aacttgttga ctttggtgtg      900

agtgctcagc tggacaggac tgtggggcgg agaaatacgt tcataggcac tccctactgg      960

atggctcctg aggtcatcgc ctgtgatgag aacccagatg ccacctatga ttacagaagt     1020

gatctttggt cttgtggcat tacagccatt gagatggcag aaggtgctcc ccctctctgt     1080

gacatgcatc caatgagagc actgtttctc attcccagaa accctcctcc ccggctgaag     1140

tcaaaaaaat ggtcgaagaa gttttttagt tttatagaag ggtgcctggt gaagaattac     1200

atgcagcggc cctctacaga gcagcttttg aaacatcctt ttataaggga tcagccaaat     1260

gaaaggcaag ttagaatcca gcttaaggat catatagatc gtaccaggaa gaagagaggc     1320

gagaaagatg aaactgagta tgagtacagt gggagtgagg aagaagagga ggaagtgcct     1380

gaacaggaag gagagccaag ttccattgtg aacgtgcctg gtgagtctac tcttcgccga     1440

gatttcctga gactgcagca ggagaacaag gaacgttccg aggctcttcg gagacaacag     1500

ttactacagg agcaacagct ccgggagcag gaagaatata aaaggcaact gctggcagag     1560

agacagaagc ggattgagca gcagaaagaa cagaggcgac ggctagaaga gcaacaaagg     1620

agagagcggg aagctagaag gcagcaggaa cgtgaacagc gaaggagaga acaagaagaa     1680

aagaggcgtc tagaggagtt ggagagaagg cgcaaagaag aagaggagag gagacgggca     1740

gaagaagaaa agaggagagt tgaaagagaa caggagtata tcaggcgaca gctagaagag     1800

gagcagcggc acttggaagt ccttcagcag cagctgctcc aggagcaggc catgttactg     1860

catgaccata ggaggccgca cccgcagcac tcgcagcagc cgccaccacc gcagcaggaa     1920

aggagcaagc caagcttcca tgctcccgag cccaaagccc actacgagcc tgctgaccga     1980

gcgcgagagg ttcctgtgag aacaacatct cgctcccctg ttctgtcccg tcgagattcc     2040

ccactgcagg gcagtgggca gcagaatagc caggcaggac agagaaactc caccagtatt     2100

gagcccaggc ttctgtggga gagagtggag aagctggtgc ccagacctgg cagtggcagc     2160

tcctcagggt ccagcaactc aggatcccag cccgggtctc accctgggtc tcagagtggc     2220

tccggggaac gcttcagagt gagatcatca tccaagtctg aaggctctcc atctcagcgc     2280

ctggaaaatg cagtgaaaaa acctgaagat aaaaaggaag ttttcagacc cctcaagcct     2340

gctggcgaag tggatctgac cgcactggcc aaagagcttc gagcagtgga agatgtacgg     2400

ccacctcaca aagtaacgga ctactcctca tccagtgagg agtcggggac gacggatgag     2460

gaggacgacg atgtggagca ggaaggggct gacgagtcca cctcaggacc agaggacacc     2520

agagcagcgt catctctgaa tttgagcaat ggtgaaacgg aatctgtgaa aaccatgatt     2580

gtccatgatg atgtagaaag tgagccggcc atgaccccat ccaaggaggg cactctaatc     2640

gtccgccaga ctcagtccgc tagtagcaca ctccagaaac acaaatcttc ctcctccttt     2700

acacctttta tagaccccag attactacag atttctccat ctagcggaac aacagtgaca     2760

tctgtggtgg gattttcctg tgatgggatg agaccagaag ccataaggca agatcctacc     2820

cggaaaggct cagtggtcaa tgtgaatcct accaacacta ggccacagag tgacaccccg     2880

gagattcgta aatacaagaa gaggtttaac tctgagattc tgtgtgctgc cttatgggga     2940

gtgaatttgc tagtgggtac agagagtggc ctgatgctgc tggacagaag tggccaaggg     3000

aaggtctatc ctcttatcaa ccgaagacga tttcaacaaa tggacgtact tgagggcttg     3060

aatgtcttgg tgacaatatc tggcaaaaag gataagttac gtgtctacta tttgtcctgg     3120

ttaagaaata aaatacttca caatgatcca gaagttgaga agaagcaggg atggacaacc     3180

gtaggggatt tggaaggatg tgtacattat aaagttgtaa aatatgaaag aatcaaattt     3240

ctggtgattg ctttgaagag ttctgtggaa gtctatgcgt gggcaccaaa gccatatcac     3300

aaatttatgg cctttaagtc atttggagaa ttggtacata agccattact ggtggatctc     3360

actgttgagg aaggccagag gttgaaagtg atctatggat cctgtgctgg attccatgct     3420

gttgatgtgg attcaggatc agtctatgac atttatctac caacacatgt aagaaagaac     3480

ccacactcta tgatccagtg tagcatcaaa ccccatgcaa tcatcatcct ccccaataca     3540

gatggaatgg agcttctggt gtgctatgaa gatgaggggg tttatgtaaa cacatatgga     3600

aggatcacca aggatgtagt tctacagtgg ggagagatgc ctacatcagt agcatatatt     3660

cgatccaatc agacaatggg ctggggagag aaggccatag agatccgatc tgtggaaact     3720

ggtcacttgg atggtgtgtt catgcacaaa agggctcaaa gactaaaatt cttgtgtgaa     3780

cgcaatgaca aggtgttctt tgcctctgtt cggtctggtg gcagcagtca ggtttatttc     3840

atgaccttag gcaggacttc tcttctgagc tggtagaagc agtgtgatcc agggattact     3900

ggcctccaga gtcttcaaga tcctgagaac ttggaattcc ttgtaactgg agctcggagc     3960

tgcaccgagg gcaaccagga cagctgtgtg tgcagacctc atgtgttggg ttctctcccc     4020

tccttcctgt tcctcttata taccagttta tccccattct tttttttttt cttactccaa     4080

aataaatcaa ggctgcaatg cagctggtgc tgttcagatt ctaccatcag gtgctataag     4140

tgtttgggat tgagcatcat actggaaagc aaacaccttt cctccagctc cagaattcct     4200

tgtctctgaa tgactctgtc ttgtgggtgt ctgacagtgg cgacgatgaa catgccgttg     4260

gttttattgg cagtgggcac aaggaggtga gaagtggtgg taaaaggagc ggagtgctga     4320

agcagagagc agatttaata tagtaacatt aacagtgtat ttaattgaca tttctttttt     4380

gtaatgtgac gatatgtgga caaagaagaa gatgcaggtt taagaagtta atatttataa     4440

aatgtgaaag acacagttac taggataact tttttgtggg tggggcttgg gagatggggt     4500

ggggtgggtt aaggggtccc attttgtttc tttggatttg gggtgggggt cctggccaag     4560

aactcagtca tttttctgtg taccaggttg cctaaatcat gtgcagatgg ttctaaaaaa     4620

aaaaaaaaaa aaaaaaaaaa aaggaaaaaa aaaaagaaaa agaaaacgtg tgcattttgt     4680

ataatggcca gaactttgtc gtgtgacagt attagcactg cctcagttaa aggtttaatt     4740

tttgtttaaa cctagacgtg caacaaaagt tttaccacag tctgcacttg cagaagaaag     4800

aaaaaaattc aaaccacatg tttatttttt ttttgcctac ctcattgttc ttaatgcatt     4860

gagaggtgat ttagtttata tgtttttgga agaaaccatt aatgtttaat ttaatcttaa     4920

taccaaaacg accagattga agtttgactt ttattgtcac aaatcagcag gcacaagaac     4980

tgtccatgaa gatgggaaat agccttaagg ctgatgcagt ttacttacaa gtttagaaac     5040

cagaatgctt tgtttttacc agattcacca ttagaggttg atggggcaac tgcagcccat     5100

gacacaagat ctcattgttc tcgatgtaga ggggttggta gcagacaggt ggttacatta     5160

gaatagtcac acaaactgtt cagtgttgca ggaacctttt cttgggggtg ggggagtttc     5220

ccttttctaa aaatgcaatg cactaaaact attttaagaa tgtagttaat tctgcttatt     5280

cataaagtgg gcatcttctg tgttttaggt gtaatatcga agtcctggct tttctcgttt     5340

tctcacttgc tctcttgttc tctgtttttt taaaccaatt ttactttatg aatatattca     5400

tgacatttgt aataaatgtc ttgagaaaga atttgtttca tggcttcatg gtcatcactc     5460

aagctcccgt aaggatatta ccgtctcagg aaaggatcag gactccatgt cacagtcctg     5520

ccatcttact ttcctcttgt cgagttctga gtggaaataa ctgcattatg gctgctttaa     5580

cctcagtcat caaaagaaac ttgctgtttt ttaggcttga tctttttcct ttgtggttaa     5640

ttttcctgta tattgtgaaa atgggggatt ttccctctgc tcccacccac ctaaacacag     5700

cagccatttg tacctgtttg cttcccatcc cacttggcac ccactctgac ctcttgtcag     5760

tttcctgttc ctggttccat ctttttgaaa aaggccctcc tttgagctac aaacatctgg     5820

taagacaagt acatccactc atgaatgcag acacagcagc tggtggtttt gtgtatacct     5880

gtaaagacaa gctgagaagc ttactttttg gggaagtaaa agaagatgga aatggatgtt     5940

tcatttgtat gagtttggag cagtgctgaa ggccaaagcc gcctactggt ttgtagttaa     6000

cctagagaag gttgaaaaat taatcctacc tttaaaggga tttgaggtag gctggattcc     6060

atcgccacag gactttagtt agaattaaat tcctgcttgt aatttatatc catgtttagg     6120

cttttcataa gatgaaacat gccacagtga acacactcgt gtacatatca agagaagaag     6180

gaaaggcaca ggtggagaac agtaaaaggt gggcagatgt ctttgaagaa atgctcaatg     6240

tctgatgcta agtgggagaa ggcagagaac aaaggatgtg gcataatggt cttaacatta     6300

tccaaagact tgaagctcca tgtctgtaag tcaaatgtta cacaaaaaaa aatgcaaatg     6360

gtgtttcatt ggaattacca agtgcttaga acttgctggc tttcccatag gtggtaaagg     6420

ggtctgagct cacaccgagt tgtgcttggc ttgcttgtgc agctccaggc acccggtggg     6480

cactctggtg gtgtttgtgg tgaactgaat tgaatccatt gttgggctta agttactgaa     6540

attggaacac cctttgtcct tctcggcggg ggcttcctgg tctgtgcttt acttggcttt     6600

tttccttccc gtcttagcct cacccccttg tcaaccagat tgagttgcta tagcttgatg     6660

cagggaccca gtgaagtttc tccgttaaag attgggagtc gtcgaaatgt ttagattctt     6720

ttaggaaagg aattattttc ccccctttta cagggtagta acttctccac agaagtgcca     6780

atatggcaaa attacacaag aaaacagtat tgcaatgaca ccattacata aggaacattg     6840

aactgttaga ggagtgctct tccaaacaaa acaaaaatgt ctctaggttt agtcagagct     6900

ttcacaagta ataacctttc tgtattaaaa tcagagtaac cctttctgta ttgagtgcag     6960

tgttttttac tcttttctca tgcacatgtt acgttggaga aaatgtttac aaaaatggtt     7020

ttgttacact aatgcgcacc acatatttat ggtttatttt aagtgacttt ttatgggtta     7080

tttaggtttt cgtcttagtt gtagcacact taccctaatt ttgccaatta ttaatttgct     7140

aaatagtaat acaaatgaca aactgcatta aatttactaa ttataaaagc tgcaaagcag     7200

actggtggca agtacacagc cctttttttt gcagtgctaa cttgtctact gtgtattatg     7260

aaaattactg ttgtcccccc accctttttt ccttaaataa agtaaaaatg acacctaaaa     7320

aaaaaaaaaa aaaa                                                       7334


<210>  610
<211>  2816
<212>  DNA
<213>  homo sapiens

<400>  610
agagggatgc gggcggcaga gctcgagagg cggctgccgg gctgcggggc gccttgactc       60

tccctccacc ctgcctcctc gggctccact cgtctgcccc tggactcccg tctcctcctg      120

tcctccggct tcccagagct ccctccttat ggcagcagct tcccgcgtct ccggcgcagc      180

ttctcagcgg acgaccctct cgctccgggg ctgagcccag tccctggatg ttgctgaaac      240

tctcgagatc atgcgcgggt ttggctgctg cttccccgcc gggtgccact gccaccgccg      300

ccgcctctgc tgccgccgtc cgcgggatgc tcagtagccc gctgcccggc ccccgcgatc      360

ctgtgttcct cggaagccgt ttgctgctgc agagttgcac gaactagtca tggtgctgtg      420

ggagtccccg cggcagtgca gcagctggac actttgcgag ggcttttgct ggctgctgct      480

gctgcccgtc atgctactca tcgtagcccg cccggtgaag ctcgctgctt tccctacctc      540

cttaagtgac tgccaaacgc ccaccggctg gaattgctct ggttatgatg acagagaaaa      600

tgatctcttc ctctgtgaca ccaacacctg taaatttgat ggggaatgtt taagaattgg      660

agacactgtg acttgcgtct gtcagttcaa gtgcaacaat gactatgtgc ctgtgtgtgg      720

ctccaatggg gagagctacc agaatgagtg ttacctgcga caggctgcat gcaaacagca      780

gagtgagata cttgtggtgt cagaaggatc atgtgccaca gatgcaggat caggatctgg      840

agatggagtc catgaaggct ctggagaaac tagtcaaaag gagacatcca cctgtgatat      900

ttgccagttt ggtgcagaat gtgacgaaga tgccgaggat gtctggtgtg tgtgtaatat      960

tgactgttct caaaccaact tcaatcccct ctgcgcttct gatgggaaat cttatgataa     1020

tgcatgccaa atcaaagaag catcgtgtca gaaacaggag aaaattgaag tcatgtcttt     1080

gggtcgatgt caagataaca caactacaac tactaagtct gaagatgggc attatgcaag     1140

aacagattat gcagagaatg ctaacaaatt agaagaaagt gccagagaac accacatacc     1200

ttgtccggaa cattacaatg gcttctgcat gcatgggaag tgtgagcatt ctatcaatat     1260

gcaggagcca tcttgcaggt gtgatgctgg ttatactgga caacactgtg aaaaaaagga     1320

ctacagtgtt ctatacgttg ttcccggtcc tgtacgattt cagtatgtct taatcgcagc     1380

tgtgattgga acaattcaga ttgctgtcat ctgtgtggtg gtcctctgca tcacaaggaa     1440

atgccccaga agcaacagaa ttcacagaca gaagcaaaat acagggcact acagttcaga     1500

caatacaaca agagcgtcca cgaggttaat ctaaagggag catgtttcac agtggctgga     1560

ctaccgagag cttggactac acaatacagt attatagaca aaagaataag acaagagatc     1620

tacacatgtt gccttgcatt tgtggtaatc tacaccaatg aaaacatgta ctacagctat     1680

atttgattat gtatggatat atttgaaata gtatacattg tcttgatgtt ttttctgtaa     1740

tgtaaataaa ctatttatat cacacaatat agttttttct ttcccatgta tttgttatat     1800

ataataaata ctcagtgatg agaaaaaatt ggcattctta aatttgcggt atctcataac     1860

tgtaaatata atcagactag tacaatctgt acagctacca atatttcatg tttcttctca     1920

tcttgagaca gcacattagt tcgtacagga ctcagtggct aggttttgaa tgattccaag     1980

atcaagggaa atgatggtta ttggaaaaga gaaaaaataa tttactttat atcgagtgag     2040

gataaaatat ttccgatctt tgaatcatct ctatttcatc aactttcttc cctggtcttc     2100

cattttcatc cctagagcag aaaaatctct ggcatataaa ctaaataaaa gaagaagggg     2160

agggaaagtg ttttataact cataaaggag agggaaagaa aatattggtt tttattgggg     2220

aagtagctta gaatccccca gttaagtgca tatatctgaa cttactgaac aagttacata     2280

ctaggtatac acagagtggc aaaatatatt ccatttaggt gggtggaatt accaggggaa     2340

aaatgtaata acaccactag atgtgaaaca ccaaaatcgt gaattctcaa aagcaccata     2400

caatatgtat agtatatagt tctttgaaaa gaagttagaa tcacaaccaa taccccatga     2460

atagctttgt ggctaatgca gcaccataat ttgtaatgga actaagatga tgatgacgat     2520

atttcatgaa aacagagaga tgttttgagc atatttatgt ggtgaggtaa gaaagaaaat     2580

taatcctata gcatctgaaa gacctcactg ggaagttggt atggattttt gtttgatttg     2640

tgcatacaaa taggtatcac aacttgatct ggaaaaaata agctgtgaaa attctcaagg     2700

aataagatga aaataaatca attattatca tttagctctg caaagctttc catggctaac     2760

acagtaaatt taaataaagc tctctttgtc tccttcaaaa aaaaaaaaaa aaaaaa         2816


<210>  611
<211>  5837
<212>  DNA
<213>  homo sapiens

<400>  611
cccgctctgc ttcagcgcac gctgaagacg gcactaggac ccagggaagt ccccgagcgg       60

ggttcgcgga aaggcagcca gactcctcct tatctccagt gtcaaacttg acatcagcct      120

gcgagcggag catggtaact tctccagcaa tcagagcgct ccccctcaca tcagtggcat      180

gcttcatgga gatatgctcc tctcactgcc ctctgcacca gcaacatgga ttgtcagctc      240

tccatcctcc tccttctcag ctgctctgtt ctcgacagct tcggggaact gattccgcag      300

ccttccaatg aagtcaatct actggattca aaaacaattc aaggggagct gggctggatc      360

tcttatccat cacatgggtg ggaagagatc agtggtgtgg atgaacatta cacacccatc      420

aggacttacc aggtgtgcaa tgtcatggac cacagtcaaa acaattggct gagaacaaac      480

tgggtcccca ggaactcagc tcagaagatt tatgtggagc tcaagttcac tctacgagac      540

tgcaatagca ttccattggt tttaggaact tgcaaggaga cattcaacct gtactacatg      600

gagtctgatg atgatcatgg ggtgaaattt cgagagcatc agtttacaaa gattgacacc      660

attgcagctg atgaaagttt cactcaaatg gatcttgggg accgtattct gaagctcaac      720

actgagatta gagaagtagg tcctgtcaac aagaagggat tttatttggc atttcaagat      780

gttggtgctt gtgttgcctt ggtgtctgtg agagtatact tcaaaaagtg cccatttaca      840

gtgaagaatc tggctatgtt tccagacacg gtacccatgg actcccagtc cctggtggag      900

gttagagggt cttgtgtcaa caattctaag gaggaagatc ctccaaggat gtactgcagt      960

acagaaggcg aatggcttgt acccattggc aagtgttcct gcaatgctgg ctatgaagaa     1020

agaggtttta tgtgccaagc ttgtcgacca ggtttctaca aggcattgga tggtaatatg     1080

aagtgtgcta agtgcccgcc tcacagttct actcaggaag atggttcaat gaactgcagg     1140

tgtgagaata attacttccg ggcagacaaa gaccctccat ccatggcttg tacccgacct     1200

ccatcttcac caagaaatgt tatctctaat ataaacgaga cctcagttat cctggactgg     1260

agttggcccc tggacacagg aggccggaaa gatgttacct tcaacatcat atgtaaaaaa     1320

tgtgggtgga atataaaaca gtgtgagcca tgcagcccaa atgtccgctt cctccctcga     1380

cagtttggac tcaccaacac cacggtgaca gtgacagacc ttctggcaca tactaactac     1440

acctttgaga ttgatgccgt taatggggtg tcagagctga gctccccacc aagacagttt     1500

gctgcggtca gcatcacaac taatcaggct gctccatcac ctgtcctgac gattaagaaa     1560

gatcggacct ccagaaatag catctctttg tcctggcaag aacctgaaca tcctaatggg     1620

atcatattgg actacgaggt caaatactat gaaaagcagg aacaagaaac aagttatacc     1680

attctgaggg caagaggcac aaatgttacc atcagtagcc tcaagcctga cactatatac     1740

gtattccaaa tccgagcccg aacagccgct ggatatggga cgaacagccg caagtttgag     1800

tttgaaacta gtccagactc tttctccatc tctggtgaaa gtagccaagt ggtcatgatc     1860

gccatttcag cggcagtagc aattattctc ctcactgttg tcatctatgt tttgattggg     1920

aggttctgtg gctataagtc aaaacatggg gcagatgaaa aaagacttca ttttggcaat     1980

gggcatttaa aacttccagg tctcaggact tatgttgacc cacatacata tgaagaccct     2040

acccaagctg ttcatgagtt tgccaaggaa ttggatgcca ccaacatatc cattgataaa     2100

gttgttggag caggtgaatt tggagaggtg tgcagtggtc gcttaaaact tccttcaaaa     2160

aaagagattt cagtggccat taagaccctg aaagttggct acacagaaaa gcagaggaga     2220

gacttcctgg gagaagcaag cattatggga cagtttgacc accccaatat cattcgactg     2280

gaaggagttg ttaccaaaag taagccagtt atgattgtca cagaatacat ggagaatggt     2340

tccttggata gtttcctacg taaacacgat gcccagttta ctgtcattca gctagtgggg     2400

atgcttcgag ggatagcatc tggcatgaag tacctgtcag acatgggcta tgttcaccga     2460

gacctcgctg ctcggaacat cttgatcaac agtaacttgg tgtgtaaggt ttctgatttc     2520

ggactttcgc gtgtcctgga ggatgaccca gaagctgctt atacaacaag aggagggaag     2580

atcccaatca ggtggacatc accagaagct atagcctacc gcaagttcac gtcagccagc     2640

gatgtatgga gttatgggat tgttctctgg gaggtgatgt cttatggaga gagaccatac     2700

tgggagatgt ccaatcagga tgtaattaaa gctgtagatg agggctatcg actgccaccc     2760

cccatggact gcccagctgc cttgtatcag ctgatgctgg actgctggca gaaagacagg     2820

aacaacagac ccaagtttga gcagattgtt agtattctgg acaagcttat ccggaatccc     2880

ggcagcctga agatcatcac cagtgcagcc gcaaggccat caaaccttct tctggaccaa     2940

agcaatgtgg atatcactac cttccgcaca acaggtgact ggcttaatgg tgtctggaca     3000

gcacactgca aggaaatctt cacgggtgtg gagtacagtt cttgtgacac aatagccaag     3060

atttccacag atgacatgaa aaaggttggt gtcaccgtgg ttgggccaca gaagaagatc     3120

atcagtagca ttaaagctct agaaacgcaa tcaaagaatg gcccagttcc cgtgtaaagc     3180

acgggacgga agtgcttctg gacggaagtg gtggctgtgg aaggcgtagc atcatcctgc     3240

agacagacaa taattctgga gatactggtg gaagttccaa gtccaataag acactcaaat     3300

atgagtacaa atgccttaaa atggaattga aaaactcttt attttcccct atcatttatt     3360

ggatgggtgg gtggggtatt tttttgtaat tgctttttta aatattagtt aatggattaa     3420

atttaattct tcagcgtaaa atggtgaaga actagcatat agccattgat cataaactga     3480

ctatcataaa atcaaaacaa gtgaaataac aaaatggaca tggtggcttt gtttaggtag     3540

agccacaaaa gaaaagactt gtaatatttt tatatacaga ggaaatctgt aacaggtatt     3600

ttgtttcttt taaagcaagc aacacagagg aatttatacc tcaaactatc tggccatatt     3660

tactacctta tcactgcatt attctctttt atctgtttaa agcatataga gatgaagttt     3720

gtagttgttt taagtactac acatttttaa attgttagct tccttaagta tatcatgtaa     3780

agaaatgtct taatttttga aaaaagtaca tatttatttt cttttgaatt gtttttattg     3840

ttttctattt atgccttgat gatttaatat ggatttgtta cagccaagtg ccaaatgctc     3900

tctcaaattg tcagcaattt aactagacac agataataat gggtttcttt cagatttttt     3960

gaaccatcca cttacatata tttttaaaaa atgaaatcct tttcctgttc atacactaac     4020

caaatctctc aaatctgtta tcccaatcat tgttgcctct ccgtttatta taaactgtat     4080

gctcacaact tagtgtaata taccagcttg tatgcaatgg attttcaacc agataacata     4140

cctttcctgc tctggtgctt agagactatc aactccctcc tttagtgaag gagccgtgtt     4200

agagcttccg agaatagctc cactggagag aagtggaatc ctatatagaa tgctgcacta     4260

attgacaaca cagcctatag gccaatgcat gagtaaaaaa aaaaacaatt actggctcac     4320

tggctttgaa aagtcactta ctattgttgc tgaaacttgc tgagctgttt atagagaatg     4380

atgataacag aacttttcct ctgtatcact ggtgtttagg tgaattaatt aaacattgtg     4440

atcattagta ccaggtatta ttatctttaa gagtcttcca cttcaatgca catggtgcag     4500

ttttggtgtg taacttagaa ggattgaact tctttgaatt tactggacat aacattttca     4560

gaatagttgg tcatctagca accgcctcaa aatgtgtaag caggagagaa atttctcatc     4620

acagggattt agacttacta ttacataaag gctaactatg agcttgctca ttaattttga     4680

aaagatgtac ctggtggata tctagctagt aatatattct gaagcaacat tttagctcta     4740

ttgatactct ttctaatgct gatatgatct tgagtataag aaatgcatat gtcactagaa     4800

tggataaaat aatgctgcaa acttaatgtt cttatgcaaa atggaacgct aatgaaacac     4860

agcttacaat cgcaaatcaa aactcacaag tgctcatctg ttgtagattt agtgtaataa     4920

gacttagatt gtgctccttc ggatatgatt gtttctcaaa tcttggcaat attccttagt     4980

caaatcaggc tactagaatt ctgtattgga tatataagag catgaaattt ttaaaaatac     5040

acttgtgatt ataaaattaa tcacaaattt cacttatacc tgctatcagc agctagaaaa     5100

catttttttt ttaaatcaag tattttgtgt ttggaatgtt agaatgagat ctgaatgtgg     5160

tttcaatcta attttttccc agactactat tttctttttt aggtactatt ctgagcatac     5220

tcaacaaaac ccatgcattt cataaactaa tagaagttga ggattgttga atctatttca     5280

cttattttgg ctgtggtttc catctgaaag tagaggttgt atacaccata tactgttctt     5340

cattttatta atatttttct ccttgacctc tcataaattt actttacaca attcttaccc     5400

tgtacatatg taaacataag tgtacgattc ttaaccatgg agtagaggta ctagaatgct     5460

tacggccatc tctttgtaca ggaactgcat tgactttcag taaacataaa gccacaactc     5520

ctacatgatg ttatgtacca tatgatctgt tttgtatctt aaatttgatt tacatatatt     5580

atttatttct ggtaactcac tcagtttatg ctgtgctaaa tatcaatcaa gccatgtata     5640

aatgtgatat gattggcaat atgtgtttac tttaaacttg tcttttcaaa atattactca     5700

gtttatgttg tacaatgtag atggcctctt actaatgtaa aatgatttgt agtggaaaca     5760

tttatatttt tataataaac ataatgaaaa tattttttac agattggaaa aaaaaaaaaa     5820

aaaaaaaaaa aaaaaaa                                                    5837


<210>  612
<211>  1476
<212>  DNA
<213>  homo sapiens

<400>  612
ccccgccggg ctcgcgccgc agaggccggt gaggcgccgg cggccacgcc gcggaaggcg       60

cgggccgagc agagccgggc gttggagccc gcgcgcgcat ggaggcgttg ccggcagccc      120

cctgagggca gcggggagac aagacccggc gacctcgcgc atccctcgag ccgccacgcg      180

ctctcgccac cgggcggcga cgggccgcgg agccggcgcg gccatggcga cgggcggcca      240

gcagaaggag aacacgctgc ttcacctctt cgccggcggg tgtggaggca cagttggtgc      300

tattttcact tgtccactag aagtcattaa gacacggttg cagtcttcaa gattagctct      360

ccggacagtc tactatcctc aggttcatct ggggaccatt agtggagctg gaatggtgag      420

accaacatcc gtgacacctg gactctttca ggttctgaag tcgatcttgg agaaagaggg      480

accaaagtca ctttttagag gcttgggtcc aaatttggtt ggagttgcac catcaagggc      540

tgtatacttt gcatgttact ccaaagccaa agagcaattt aatggcattt tcgtgcctaa      600

cagcaatatt gtgcatattt tctcagctgg ctctgcagct tttatcacaa attccttaat      660

gaatcctata tggatggtta aaacccgaat gcagctagaa cagaaagtga ggggctctaa      720

gcagatgaat acactccagt gtgctcgtta cgtttaccag accgaaggca ttcgtggctt      780

ctatagagga ttaactgcct cgtatgctgg aatttccgaa actataatct gctttgctat      840

ttatgaaagt ttaaagaagt atctgaaaga agctccatta gcctcttctg caaatgggac      900

tgagaaaaat tccacaagtt tttttggact tatggcagct gctgctcttt ctaagggctg      960

tgcctcctgc attgcttatc cacacgaagt cataaggacg aggctccggg aagagggcac     1020

caagtacaag tcttttgtcc agacggcgcg cctggtgttc cgggaagaag gctaccttgc     1080

cttttataga ggactgtttg cccagcttat ccggcagatc ccaaatactg ccattgtgtt     1140

gtctacttat gagttaattg tgtacctgtt agaagaccgt actcagtaac aggccggaaa     1200

attgtgctct agaagaataa aactgaaaaa ctctagagaa ttttttttcc ccattgatgt     1260

ttagaaagtt tgagactgaa acaggaaagg ccataaaata tctggttcat atcacctgtt     1320

ggacatttcc ttttggattc atgctttctg gaaggtttaa attcattaac gttaatagtt     1380

aattataact ttttttttaa cttaagagga ttcagggtta agcaccaact aaattaaatc     1440

atgctattta atttaagtat aaaaaaaaaa aaaaaa                               1476


<210>  613
<211>  6730
<212>  DNA
<213>  homo sapiens

<400>  613
aataaagaac gaggacactg cggggtgtgc ggcggcccaa gcggtttcaa acggcttaga       60

gcaggccgct tggttctgac ccagctgagg aaatactctt aattctaagg aaaacctgga      120

agcacaatgg gagatgacag tgagtggttg aaactgccag ttgatcagaa atgtgaacac      180

aagctgtgga aagcaaggtt aagtgggtat gaagaggccc tgaagatctt ccagaaaata      240

aaggatgaaa agagcccaga gtggtccaaa tttttaggat tgatcaaaaa atttgtcact      300

gattccaatg cagtggttca attgaaagga ttagaagctg cacttgttta tgttgaaaat      360

gcccatgtag caggaaaaac cacaggagaa gttgtgtcag gtgttgtaag taaggtgttc      420

aatcaaccta aagctaaagc caaggagctg ggcatagaga tctgtcttat gtacatagag      480

attgagaaag gagaggctgt tcaagaagag ctcctgaaag gcttggacaa taagaatccc      540

aagatcatag tggcctgtat agagacactg aggaaagcct taagtgaatt tggttccaaa      600

atcatcttgc ttaagccaat tatcaaagtg ttgccaaaac tctttgagtc tcgagagaag      660

gctgttcgag atgaagccaa actaattgct gtggagattt acagatggat tcgggatgct      720

ctgagacccc cattacaaaa tataaactct gttcagttga aagaactaga agaagaatgg      780

gtcaaactgc caacaagtgc tcctagacct actcgatttc ttcgttccca acaagaacta      840

gaagctaaat tggaacaaca acagtctgct ggtggagatg ctgaaggagg tggtgatgat      900

ggtgatgagg tgccacaaat agatgcttat gagcttttag aagctgtaga aatcctttcc      960

aaacttccca aagactttta tgacaaaatt gaggcaaaaa aatggcaaga gagaaaagag     1020

gccctggagt ctgtagaagt actaataaaa aaccccaaac tggaagctgg cgattatgca     1080

gatttagtaa aagcattaaa gaaggttgtt ggaaaggaca ccaatgtcat gttggtggct     1140

ttggcagcaa aatgtcttac tggcctggct gttgggctaa ggaagaaatt tggacaatat     1200

gcaggacatg ttgtgccaac catcttggag aaattcaaag agaagaaacc tcaagtggta     1260

caagccctgc aggaggcaat tgatgcaatc ttccttacta ccacactaca gaacatcagt     1320

gaggatgttt tagcagtaat ggataataaa aatccaacca tcaagcagca gacatctctt     1380

tttattgcaa gaagtttccg ccactgcact gcttctaccc tgccaaagag cttgctaaag     1440

cccttttgtg ctgcactact taagcacatc aatgattctg ctcctgaagt cagagatgcc     1500

gcatttgaag cattgggtac tgctttgaag gtggttggcg agaaagcagt aaacccattc     1560

ctagctgatg tggacaaact caagcttgat aagatcaaag aatgttcaga aaaggtagaa     1620

ctgatacatg gtaagaaagc tggactagct gctgataaga aggaattcaa acctctgcct     1680

ggaaggactg ctgcttcagg ggctgcagga gataaggaca caaaggacat ttctgcaccc     1740

aaaccaggac ctctaaaaaa ggcacctgct gctaaggctg gtgggccacc aaaaaagggg     1800

aaaccagctg caccaggagg cgcagggaat actggaacca agaacaagaa aggactggag     1860

actaaagaaa tagtggagcc tgagctctcg atagaagtat gtgaagaaaa agcttcagct     1920

gttcttcccc ctacctgtat acagcttctt gacagcagta actggaaaga aaggctggct     1980

tgtatggaag agttccagaa ggctgttgag ctaatggacc gaactgaaat gccatgccag     2040

gcattagtga ggatgctagc caagaaacct ggatggaaag aaactaattt tcaggtgatg     2100

caaatgaagc ttcatatagt tgctttgatt gcccagaagg gaaatttttc caaaacgtca     2160

gctcaggttg tattagatgg ccttgtggac aagattggag atgtgaaatg tgggaacaat     2220

gcaaaagaag ctatgacagc aatagccgaa gcctgtatgt taccatggac tgctgaacag     2280

gttgtgtcaa tggctttctc acaaaagaat cccaaaaatc agtcagaaac tctgaattgg     2340

ctatcaaatg ccataaaaga atttggtttt tctgggttga atgtcaaagc tttcattagc     2400

aatgtgaaga cagctcttgc tgcaacaaac ccagctgtga ggactgctgc cataaccctg     2460

cttggcgtga tgtatctgta tgttggtccc tctttgcgaa tgttctttga ggatgagaag     2520

cctgccctcc tatcccagat agatgcagaa tttgagaaga tgcagggaca aagtccacct     2580

gctccaacca gaggaatttc caagcatagc acaagtggta cagatgaagg agaagatgga     2640

gatgaaccag atgacgggag caatgatgtc gttgatcttt tgccgaggac ggagatcagt     2700

gataaaatca cttcagagtt ggtatctaag attggtgata agaattggaa gattaggaaa     2760

gaaggcctag atgaagtggc aggtattatt aatgacgcaa aatttatcca accgaatata     2820

ggtgaacttc caactgcctt gaagggtcga ctcaatgatt caaataaaat cttggtacag     2880

caaacgctga atatcctgca acaactggca gtagccatgg gcccaaatat taagcaacat     2940

gtaaaaaatt taggcatccc tatcatcaca gtccttggag acagcaagaa caatgttcga     3000

gctgctgccc tagcgactgt gaatgcttgg gcagaacaga ctggcatgaa ggaatggctg     3060

gaaggagaag atctttctga agagctcaaa aaggaaaatc ctttcttgag gcaagagctt     3120

ctgggctggc tggctgagaa actacctact cttcgttcca cccctacaga ccttatcctt     3180

tgtgttcctc atctctactc ctgcctagaa gatcgaaatg gagatgtgcg aaagaaggcc     3240

caagatgcct tgccattctt catgatgcat ttaggatatg aaaaaatggc caaggctact     3300

gggaaactaa agccaacttc taaagatcag gtattggcca tgctagagaa agccaaagtt     3360

aacatgccag ccaagcctgc tccacccact aaagcaactt ctaaaccaat gggagggtcc     3420

gctccagcca aattccagcc tgcatcagca cctgctgaag attgtatttc cagcagtaca     3480

gaacccaaac ctgatccaaa aaaggccaaa gctccaggat tatcctctaa agcaaagagt     3540

gcacaaggga agaagatgcc aagcaaaacc agcttaaagg aggatgaaga caaatccggg     3600

cctattttta ttgttgttcc aaatggaaaa gagcaaagga tgaaagatga aaaaggattg     3660

aaggtgctaa agtggaattt tactacccca cgggatgaat acattgagca actaaagact     3720

caaatgtcta gctgtgtggc taaatggtta caagatgaga tgtttcactc agactttcag     3780

catcataaca aagcccttgc tgttatggtt gatcacttgg agagtgaaaa agaaggagtt     3840

attggttgcc tggatcttat cttaaagtgg cttaccctga ggttttttga caccaataca     3900

agcgtcctga tgaaagcact agaatattta aaattgctct tcaccttgct aagtgaagaa     3960

gaatatcatc ttactgagaa tgaagcatct tccttcatcc cctatcttgt cgtcaaggtt     4020

ggagaaccaa aggatgtcat tcgtaaagat gttcgtgcca tcctgaaccg gatgtgcctt     4080

gtctacccag ctagcaagat gtttcccttt atcatggaag gaaccaaatc caaaaactct     4140

aagcagagag cagagtgcct ggaagagctg ggatgtctgg ttgagtccta tggcatgaat     4200

gtttgccaac caaccccagg aaaagcctta aaggaaatag ctgttcacat aggagaccgt     4260

gacaatgctg tacgcaatgc tgcactcaac accattgtaa cggtgtacaa tgtacatggg     4320

gatcaggtgt tcaaactgat tggaaatctt tctgaaaagg atatgagcat gctcgaggag     4380

aggattaagc ggtcagcaaa gagaccctct gctgcaccaa taaaacaggt ggaagagaaa     4440

cctcagcgtg cacagaacat aagctccaat gccaacatgt tacgcaaggg accagctgag     4500

gacatgtctt ccaaactcaa ccaagcccga agcatgagtg ggcatcctga ggcagcccag     4560

atggtccgcc gagaattcca gctggatcta gatgagattg agaatgacaa tggtacagtc     4620

cgatgtgaaa tgccagaact tgttcagcac aaactggatg acatttttga gccagtcctt     4680

attcctgaac ccaagatccg ggctgtttct ccacacttcg atgacatgca cagtaataca     4740

gcatccacaa tcaatttcat tatctcccaa gtagccagtg gtgacatcaa cacaagtatc     4800

caagctctga cacagatcga tgaggtcctg agacaggaag acaaagctga agccatgtcc     4860

ggccatattg atcagtttct gatagccact tttatgcagc taagactcat ctacaacaca     4920

cacatggcag atgagaaatt ggagaaggac gagatcatca agttgtatag ctgtatcatt     4980

ggcaacatga tttcgctgtt tcagatagag agccttgccc gggaggcctc cactggagta     5040

ctaaaagacc taatgcatgg cctcatcacc ttaatgctgg attctcggat tgaagatctt     5100

gaggaaggac aacaggtcat ccgctctgtg aacctcttgg tggtgaaggt tctggagaag     5160

tcagaccaga ccaacatcct gagtgcccta cttgttttgc tccaagacag cctgctagca     5220

acagccagtt ctcccaaatt ctcagagctt gttatgaagt gtctctggag aatggttcga     5280

ctgttgcctg ataccatcaa tagcattaac ctagacagaa ttcttctgga tatccacatt     5340

ttcatgaagg tcttccccaa agagaaactg aagcaatgca aaagtgaatt tcccataagg     5400

accctaaaga ccctgctaca caccttatgc aaattaaaag ggcccaagat cctggaccac     5460

ctaacgatga tcgacaacaa aaacgagtct gagctggagg cccatctctg ccggatgatg     5520

aagcacagta tggaccagac tgggagcaag tctgataagg aaacagaaaa gggagcatct     5580

cgaatagatg aaaaatcatc aaaggccaaa gtgaatgatt tcttagctga gatttttaag     5640

aagattggct ctaaagaaaa cactaaagag ggactagcag agttatatga atataagaag     5700

aaatactcag atgctgacat tgaaccattt ctgaaaaatt cctcacagtt cttccagagc     5760

tatgtcgaaa gaggccttcg ggtgattgag atggagaggg agggcaaagg tcgtatttcc     5820

acttcaacag gcatctcccc tcagatggaa gtcacatgtg tgcccacgcc cacaagcaca     5880

gtgtcctcca taggtaacac aaatggggaa gaagtggggc catctgtcta cttggaaagg     5940

ctaaagatcc tccgacagcg atgtggtctg gacaacacaa agcaagatga ccgacctcct     6000

ttgacctctt tgctctccaa accagcagtt cctactgtcg cctcttccac agacatgctc     6060

cacagcaaac tctctcagct ccgggagtca cgggagcagc accagcattc agacctggat     6120

tctaaccaga ctcactcttc aggaactgtg acctcctcct cctccacagc taacatagac     6180

gacttgaaaa aaagactgga gagaataaag agcagtcgca aatgaagctg ccccactccc     6240

ccggcaccct gcagctttag tttactaaac tagaagtcct catagtttaa aatggcctca     6300

gcaggcctag tgtatacaaa ctggttgtat gtatcatgcc gtggagctag ggggaggagt     6360

cattgtggca caagtatttg tacatactct gcttctctct gtcagcgtcc tgctgctcta     6420

gaagactgtc cgtggatgag tttagtgtac agacttgtaa acagctgccc cctctctgct     6480

cagtctagtt cccagatcct tttcttttct ttttaattgc tcatttgtaa aattgtccta     6540

atctttccta gctttttaat agttaatatt agaaactctt taatagtttt cctttcagtt     6600

tgtgagctct tctctgtcgc cctgaagggt cactgtattc tgtatgaatg catggcatga     6660

tacaactaat ttaagagtct tttataaata aagtttgcat taactatacc tgacaaaaaa     6720

aaaaaaaaaa                                                            6730


<210>  614
<211>  3392
<212>  DNA
<213>  homo sapiens

<400>  614
gtgcatgctg cggcagttgc aacaggagaa ccgagtacca gttgctcaac actttatcac       60

tttgcattgc tctttctcct cccttaagtg aatttccatt ttgagggtac agctccacag      120

gagaaaggaa gaaatacttg tgttggctgc atttccaggg atgctaccag agctcaaggc      180

tgtcacctgg tcttgcccag aagagccgtt cttagaggca ggacttgatg aaggctttcc      240

tgctgatgga ataggtttgc tagagctggc cttggaatta gaacccttca tgtggccttt      300

ataaatatgc gtttgagaca gagttatatg cagaagttga aaatgcctgg aagatttctg      360

gtttctttca ctacttatcc tgcctttttg catcgctgcc agatttggat gatatgatat      420

tcagaggggc accttaatca aagccattct tcaacaagac ccacctggca taagattgca      480

cacataattc aagatggcca gtcaacctcc tgaagacact gcggagtctc aggcctctga      540

tgagctggag tgcaaaatct gttacaatcg atacaatctg aaacagagga aacccaaagt      600

gctggagtgt tgtcataggg tttgtgccaa atgcctctac aagatcatag actttgggga      660

ctccccacaa ggtgtcattg tctgtccttt ctgcaggttt gagacgtgcc tgccagatga      720

tgaagttagt agcctgcccg atgacaacaa catccttgta aacttgactt gtggaggcaa      780

agggaagaag tgcctgccag agaaccctac tgagctgctg ctcaccccca agaggctggc      840

ctctctggtc agtccttctc acacgtcctc caactgcctg gtcataacca tcatggaggt      900

gcagagagag agctccccgt ccctgagctc cactcctgtg gtagaatttt ataggcctgc      960

gagtttcgac tctgtcacca ctgtgtcaca caactggact gtgtggaact gcacgtccct     1020

gctgtttcag acatccatcc gggtgttagt gtggttgcta ggtttgctct acttcagctc     1080

cttaccctta ggaatctact tactggtgtc taagaaagtc acccttgggg tcgtctttgt     1140

cagcctggtc ccttcgagcc tcgttattct tatggtgtat ggtttttgcc agtgtgtttg     1200

tcatgaattt ctagactgta tggcacctcc ttcttaactg atatgcaaaa taagaaattg     1260

gacacacatt gccctgtttg agtgtgaagt tagataattt ataatttatt ttcttttatg     1320

ttctttatga ttagtatcca tgacattaac aaaacccttg gccacatgtt gacttgattg     1380

gttttcctgt aggctggaag taaaaatgtt catttctact taggggttag caaaattgta     1440

taagctcaca cttcatggag cactgacagc agtgagtctt cccagagaaa ggacagggtt     1500

tctctcagca ctgccagaca gacggcaggg gtgtggtgtg ttatactata gggagagcat     1560

ggatccctcc tttcgtattc atggatgttc tatgatggca gttggacaca agaggaaagt     1620

tgctctgaga cacaaagtgt gtactccttt cccaccccat acccctggta ttggaacacc     1680

ctagaattgt cttcaggtgt tttctctctt aagtcactct ctgtggtcgg cgatcccatt     1740

gagatacttg tttcctctgc ccattctccc ttgccaagag gaaactcggt tccattccct     1800

tgggtagttt caactgaata ccagttttgc cacattacta aggagaatga aaagcactga     1860

ggaatttgca tcacagtcag cttcatggca gaatgtggcc atttgtcctt gagacacact     1920

ctttcctcca tgtctgtttt cctctctcct cagtcttatc tgagaagaat ggaggagaag     1980

gaacttctca tacagcggtt attattgatg aaaaccttca tttgagtctt tccttataac     2040

atcttagttt tggttttttt aaaccacatt gcccaatcag cctcacccct tgtcctgaaa     2100

aggttccatt taaattagtt gctataaatt catcaatact ttttttccct attatatttt     2160

tggttctatt aggatttact taactgaatc ttataacaat tcgaggtgaa ctgtggcaat     2220

gaaaaccaga aacagttaat gagatgcttc agctcacagt ttgaagtgct gagaacctaa     2280

gtattttgct gtacggtact gagctgtacc aaaatatgat ggtttaggtt tatgtgcaag     2340

actttgtgtt gtagtctaga caaaggggtg ggcaagagac atgcaaagct gaagccctgc     2400

ttgaaaagac ccttcaagga agtaaaatgg caggggcaga gtgcagctta acatgttgct     2460

atccctgttg tttttgagtt ggttttggaa tggattcaag ttcttacaca atttattttg     2520

aatacaagca taatctaggt gatttgagtt aatgaacttc ttttcatgat gtagggaaag     2580

ttgaatgtat atatttctaa gaagaatttg tttagcagat tacaagttgg caaaatagac     2640

tgttcacaga aactaggcaa aaatttaaaa aaacattcta gtctctaaaa cccattacta     2700

atgattaaca ttaaaatatt tgtaactctt agaaaggggg cattactaag acgactttaa     2760

cttgttatga aatctttgtt gtgtgatgca ggtacagtgc gcccattcca actggaatag     2820

cagtttgatt ttaattgtaa aactaaactt cgggaatatg tatgcccaaa gtaagtagga     2880

tgagaatagt atacatggga tatggtccaa tgaatttaag ccccaagata cagctaaata     2940

catttatgat ttcataaaat ctagtttaga tagcattgtg atgcaatttc cagaaatcca     3000

tttgtgttta gagtaaatac catgtttaga agatgttttg tggtttggat ttatatattt     3060

gtaaggtttt tttaaaaaaa tgttcgtttt gtttgaaatg taacattgag taaattggtg     3120

agttatataa tgagatttct agaaagctct ggacatgggt acgatgtgtt ttgcttctct     3180

gtataatgtc tacagtgata aacttgtgtc tccgtgtatt gtggcagtct ttttttctag     3240

ttaatttggc tttagagagc aatctttgta tgacaccaga aaactcttca tgctattgaa     3300

tgataaaaag ataatgcttt aatattttat tcactgtgat actattttgt ttgtctatta     3360

aattgttatt atttccaaat ttaaaaaaaa aa                                   3392


<210>  615
<211>  1249
<212>  DNA
<213>  homo sapiens

<400>  615
gagctgtgct tggggcgggg cctggcgtgt attcgaaagg aaggcgccgg ctgcgggaag       60

atggcggctc agccgctgcg gcatcgctca cgttgtgcaa cgccgccccg gggggacttt      120

tgtggtggca ctgagagggc gattgaccaa gcttctttta cgacctccat ggagtgggat      180

acgcaggtgg tgaaggggtc ctcgccgctc ggccccgcag ggctgggggc tgaggagcca      240

gccgccggcc cgcagctgcc gtcttggctg cagcctgaga ggtgcgctgt gttccagtgc      300

gcacagtgtc acgcagtgct cgccgactcg gtgcacctcg cctgggacct gtcgcggtcc      360

ctcggggccg tggtcttctc cagagttaca aataacgtcg ttttggaagc gcccttccta      420

gttggcattg aaggttcact caaaggcagt acttacaacc ttttattctg tggttcttgt      480

gggattcccg ttggtttcca tctgtattct acccatgctg ccctggctgc cttgagaggt      540

cacttctgcc tttccagtga caaaatggtg tgctatctct taaaaacaaa agccatagta      600

aatgcatcag agatggatat tcaaaatgtt cctctatcag aaaagattgc agagctgaaa      660

gagaagatag tgctaacgca caatcgctta aaatcactaa tgaagattct gagtgaagtg      720

actcctgacc agtccaagcc agaaaactga tcctgtacca aagcttgagt gtcaggttca      780

ggctttattg ctgtcttcaa caacaggtgc tgcttagtca tttcttgaaa aagattggct      840

tcaagaatgg aggggaaatg cagtttctat ttacctttag gctgattttc caaattattt      900

gtgaagctgt ttttagaaga tgagagacta aggattcttc tcttttatag ctatttgcct      960

taagaactta ctttagattc ttattgaatt cataatactt atctctgaaa atgtctttga     1020

ctgtaaattt aggaattaag atgcagagtc ccatgtgtcc tctgatctaa agttgcatgg     1080

ttggtctgaa aatagagttg ggcttaatgt tgacttctat tactcctgca tggagcagtt     1140

gttatgaata ctaatacatc actttttaac ttctgtaaaa tacagatcat aatattctat     1200

aggtaatgtt taataaattg cctgaataat atacaaaaaa aaaaaaaaa                 1249


<210>  616
<211>  4796
<212>  DNA
<213>  homo sapiens

<400>  616
atctttgatc aatgtacttg ccagggagag cccaagtcct tcaaacctcc tccttttcac       60

cttcatcctt aactttgtgc tagagcgaga cccacacaac aacagccgac cctccccgcc      120

ccacccccac ccccaaacca gccctcgatc ccagcccccg gagaggactc gcatttcgac      180

ttgcgggaca cttttgtgcg ttcctctcca gagcgcctct cgtgctcgcc cctcttgcgc      240

tcgctcttta ttaccttcac ctccttttct cccccttctc tccctttctc cttctcgttc      300

tctcccggag ttgttgttgc ccccctcgct ccttctcccc ccttttttcc ccttcccctc      360

ccgggggtgt gtggcaactt ttcctctcgc ttctcctccg tctgtttccc cttatatgtg      420

accatggcag tgccggcggc tttgatccct ccgacccagc tggtcccccc tcaaccccca      480

atctccacgt ctgcttcctc ctctggcacc accacctcca cctcttcggc gacttcgtct      540

ccggctcctt ccatcggacc cccggcgtcc tctgggccaa ctctgttccg cccggagccc      600

atcgcttcgg cggcggcggc ggcggccaca gtcacctcta ccggcggcgg cggcggcggc      660

ggcggcagcg gaggcggcgg cggcagcagc ggcaacggag gcggcggtgg cggcggcggc      720

ggtggcagca actgcaaccc caacctggcg gccgcgagca acggcagcgg cggcggcggc      780

ggcggcatca gcgctggcgg cggcgtcgct tccagcaccc ccatcaacgc cagcaccggc      840

agcagcagca gcagcagtag cagcagcagc agcagcagca gtagtagcag cagcagcagt      900

agcagcagca gctgcggccc cctccccggg aaacccgtgt actcaacccc gtccccagtg      960

gaaaacaccc ctcagaataa tgagtgcaaa atggtggatc tgaggggggc caaagtggct     1020

tccttcacgg tggagggctg cgagctgatc tgcctgcccc aggctttcga cctgttcctg     1080

aagcacttgg tggggggctt gcatacggtc tacaccaagc tgaagcggct ggagatcacg     1140

ccggtggtgt gcaatgtgga acaagttcgc atcctgaggg gactgggcgc catccagcca     1200

ggagtgaacc gctgcaaact catctccagg aaggacttcg agaccctcta caatgactgc     1260

accaacgcaa gttctagacc tggaaggcct cctaagagga ctcaaagtgt cacctcccca     1320

gagaactctc acatcatgcc gcattctgtc cctggtctca tgtctcctgg gataattcca     1380

ccaacaggtc tgacagcagc cgctgcagca gctgctgctg ctaccaatgc agctattgct     1440

gaagcaatga aggtgaaaaa aatcaaatta gaagccatga gcaactatca tgccagtaat     1500

aaccaacatg gagcagactc tgaaaacggg gacatgaatt caagtgtcga tgagaccccg     1560

ctttctacac caaccgcaag agacagcctt gacaaactct ctctaactgg gcatggacaa     1620

ccactgcctc caggttttcc atctcctttt ctgtttcctg atggactgtc ttccatcgag     1680

actcttctga ctaacataca ggggctgttg aaagttgcca tagataatgc cagagctcaa     1740

gagaaacagg tccaactgga aaaaactgag ctgaagatgg attttttaag ggaaagagaa     1800

ctaagggaaa cacttgagaa gcagttggct atggaacaaa agaatagagc catagttcaa     1860

aagaggctaa agaaggagaa gaaggcaaag agaaaattgc aggaagcact tgagtttgag     1920

acgaaacggc gtgaacaagc agaacagacg ctaaaacagg cagcttcaac agatagtctc     1980

agggtcttaa atgactctct gaccccagag atagaggctg accgcagtgg cggcagaaca     2040

gatgctgaaa ggacaataca agatggaaga ctgtatttga aaactactgt catgtactga     2100

atctttcctg ttgaagaaat ccatgttata gaaaagaact ttgcagtcag acattcgtca     2160

tgggaaagtt cagaaaaaaa taaagtcctt ttaagggaac ttcctgaatt ttgtgtatta     2220

atgttcttta aaagtttaag tattctacaa aaaaaaaaaa agttttctcc attgattttc     2280

acctgtggtt cataccagag acctgagaat gtttgtaaat gtacaagtat caaagttctt     2340

acagttaatt actgcaactt gctgctggac aattgtatac agagttaaag gcaggtctga     2400

ataagaccta gctttgtttt tttctaatgg aatgaaccat tttcctcttc tgaaaattct     2460

gtatctgagc acatcaagag actcttgtag cagtggttac ccagacttac agaattatgt     2520

cctccagaaa ccagcaagaa cacttggaat gaacgaatga acttgtaggg ggcatagagg     2580

attcttgaaa aaaaaaaatg caagagtgat tttctgttac attcaatttc aaactctcta     2640

attgtgggtt ttctcctgaa gaattttttt tcacatactt tccaaaagac caacaaatgg     2700

atgttgacaa caacccaatg aaataacatt ttgcatatct gaaaagaagc attgaatata     2760

agccaaaagc tttcactgaa ggtttttttt tcttaaaaat aaaaaaaaat atataagtgt     2820

aacatgtttt cattccaaac tggtagtggt atatagaatt aaagataata atgttgcttc     2880

ttattcaaac tgttggtcat atgtacagta tataaacata aaacacacaa ggaaggtatt     2940

atgtatgcag tagtatacta gagtttagga aaatgaaaat tttagaaaat atgttttgtc     3000

accctgttgg tcagaaagat gtctttctgg ttttaacgca tgcaggcatg taaatatttg     3060

tctggagtca cagtattaat gaatgagatc ttaagcatct ggtgacatca gaactctgtg     3120

tcagccactt ttatttgtat attgaaccct agctagtgcc ccaagctgca ctattgggaa     3180

tggattgtgg ctgaacagca aatcaaaaca ccagaaatat ttttatatgt taacgtcata     3240

ttatgttaat gttgctgaaa acaaaaccta acaaaccttg atgtaccagt ccaataccat     3300

gtagcgctga gtgataaagt taaaatgtgc tgtgcttccc acccttgtca gagggaaggg     3360

tggctatgtg ttattttcac tgtctttttg aaagttacag tatgtgtttt cactttcgtg     3420

cagataactg gaagtaaagc ggcaaacagt gcttattaca tgctaaagtt accttctctt     3480

tgttttttgc atatctggaa ttacaccttt aaagactgat atgaatcagt acggtcacta     3540

tacattttat gatttttctg tcatcttaaa attgtatgat cgtaacatta tttattacca     3600

caaaacagca aaatcttcaa tgtctaagaa aactagctta aaatgtttaa atatagttct     3660

gattgggtat taattacttg attaagaaaa aattaacatt atagatactc tggcattacg     3720

cttctatacc ttttaggtct tccttgcaat actggaacat aattcttttg tgtagctcac     3780

tattagccag ctaagttcat ctttttaata ccataaaaag gttatatgta cagttcctat     3840

tttagcttgc ttacaaaggg agcattattt ttatttaaag tattgctagt aaatgatttg     3900

tagaaacttg gttttctaag catagttctt ccataaccac cttttgttgt ttgagcacaa     3960

gggattcttt tcctagttct atgtgtttgt ttccctatat gcagtcttta aaggattaca     4020

acacttaaaa ttgaatggac ttgtgtcaag ctttttgcat catacatttt ttgaaagatt     4080

tttaaaaaag cctacaactt acatatgtag tagaatcagc cattgctctg ctcctggcat     4140

agagtcacct gtttgttatg tggattaaat agttttaaaa tacatatttg aagacctttg     4200

agaatgcttt agtgtttgat ttgaaataaa aggaaatttt agcaaggatt aaagaaaaaa     4260

gctatcagct gtatgttaag agagactctt actaacatgt tgtaaatatt acaattcatg     4320

aaatgttatt gtaagtctgt aacttaattt tttccctgtt ttagttatac aggttggttt     4380

ggaaatttgt gttttggcat aaacaagtaa aatgtgccca ttttatggtt tccatgcttt     4440

tgtaatccta aaaatattaa tgtctagttg ttctatatta taaccacatt tgcgctctat     4500

gcaagccctt ggaacagaac atactcatct tcatgtagga cctatgaaaa ttgtctattt     4560

ttatctatat atttaaagtt ttctaaaaat gataaaaggt tattacgaat tttgttgtac     4620

aaaatctgta caaaaatctg tttttacatc ataatgcaag aattggaaat ttttctatgg     4680

tagcctagtt atttgagcct ggtttcaatg tgagaaccac gtttactgtt attgtattta     4740

attttctttt ccttttcaac aatctcctaa taaaactgtc tgaaatctca aaaaaa         4796


<210>  617
<211>  3707
<212>  DNA
<213>  homo sapiens

<400>  617
ggcatctctc gcgtgctctt gcttgcgcac taatttgtcc tccaccgcct cccgttcagg       60

ccggctctcc tgcggggcgg ggaaaggggt gggaagaggc tgggagctgc ggccgctgtg      120

ccagggtgac cggtagagtt gtagccgagg tggcggcgcg gggcggggcg ggcggagaga      180

gaaggaagga ggtggttgtg caggatggcg acggcggcct acgagcagct gaagctgcat      240

atcacacctg aaaaatttta tgtggaagct tgtgatgatg gagcagatga cgtacttacc      300

attgaccgtg tgtccacaga ggttaccctt gcagtcaaga aagatgttcc tccttcagct      360

gtcacaagac caatatttgg tatactgggc acaatccatc tggtggcagg taattatctt      420

atagtcatta ccaaaaagat aaaagtaggt gaatttttca gtcatgtagt ctggaaagca      480

acagattttg atgtcctttc ttataagaag acaatgttgc acttaactga tattcagtta      540

caagataata aaaccttcct agcgatgcta aaccatgtct tgaatgtgga tggattttac      600

ttttcaacaa catatgattt gacccatact ttgcagcggc tatccaacac tagtcctgaa      660

ttccaagaaa tgagtctctt ggaaagggca gatcagcggt ttgtatggaa tggtcatctt      720

ctaagagaac tttctgcaca gccagaggtt catcggtttg cccttccagt gttacatggc      780

tttattacca tgcattcatg ttctattaat ggaaaatact ttgattggat tctcatctcg      840

aggaggagct gtttcagagc tggtgtgcgc tattatgtaa gaggaattga ttcggaaggc      900

catgcagcta actttgtaga aacagaacaa attgtgcact acaatgggag caaagcttcg      960

tttgtacaga ctcgaggatc aatacctgtt ttctggtccc aaagaccaaa cctcaagtac     1020

aaaccactgc cacagatcag caaagtagca aatcacatgg acggtttcca aaggcatttt     1080

gattcccaag taattattta tggaaaacaa gttataatca atctgattaa ccagaagggc     1140

tcggagaagc cacttgagca gacatttgca acaatggtgt cttccttggg aagtggaatg     1200

atgagataca ttgcctttga cttccataag gaatgtaaaa atatgagatg ggatcgacta     1260

agtattttat tggatcaggt agcagaaatg caagatgaat taagttattt tctagtggac     1320

tctgctggcc aggtggtggc aaaccaggaa ggcgtgttcc gaagcaattg catggattgt     1380

ctagatagaa ccaatgtgat ccagagtttg ttagctcgtc gttcacttca ggcccaactt     1440

cagagactag gagttttgca tgtgggacaa aagcttgaag aacaagatga atttgagaag     1500

atttacaaaa atgcctgggc tgacaacgca aatgcttgtg ccaagcaata tgcgggaact     1560

ggtgccttga agactgactt taccagaact ggaaagagaa ctcatttggg acttataatg     1620

gatggctgga actcaatgat acgatattat aagaacaact tttccgatgg atttagacaa     1680

gattccatag acttatttct tggaaactat tcagtggatg aattagaatc tcatagtcct     1740

ttaagtgttc caagggactg gaaattcctg gctttgccta ttatcatggt tgttgccttt     1800

tcaatgtgca ttatctgttt gcttatggct ggtgacactt ggacagaaac actggcctat     1860

gtgctcttct ggggagttgc aagcattgga acatttttta tcattcttta caatggcaaa     1920

gattttgtcg atgctcccag actggtccag aaagaaaaga tagactgaat ttgtatttgt     1980

ggaaagcggc ttggcttgga agattccatt gtgcagaact ggagtcttta ctgacccgct     2040

ttccacatca gcccaaggtc tttttaatgc ctttatccaa aagcacatct tgtgctccat     2100

gcaggatgat gacagaattg atctgatgtt actgccttga tggtctcttt actattggga     2160

cagttagatt tataatttga agctattctg taattaaaat ataacctgaa ttcagcttgc     2220

agaatggaag ctgaatctgt tcattgtatt ctattgattg tcaatttaat tagctgttgc     2280

agaataagta atatatttta aaaacctagc tcctttcatt atttaaaaca gcaaaattat     2340

ttttgtagct cagtttcatt attgtcattg tagaagcggt cactattagc aggcatactt     2400

ttccacacat ctttggactt ttcttaaaag ttcagtaata agctaactgt gtttataaaa     2460

tgtaagtctc ttacagacat caagtagttt gatgagacag tctgtgactt catgatagga     2520

aagaggagga tgaggtctgg ggttctttaa agtctctggt gggctgcctc atgactttaa     2580

tcagcttgaa ctgccagtgc accagcagtt taggtgtgat gagagaattc agatatactt     2640

tatcttttta aaaaagtgta aataaaatca aagaatgtaa agtctatctc ttacgctaga     2700

ggtccaaagc tgcctctgtt ttaaagatta tcccaatgtg gaagatgccc atgactggtc     2760

agctacttcc tcctatacat tttggtttct ttgagggtca ctcattgaga cacgcaggcc     2820

tctgagaggg tcttgttcta gatttcatat tgcacttgga gggtaacagc tgctttttca     2880

cgcatggtac tcttgatgtt tttcactctg tcaaggattt tgttggctat caatgaatgt     2940

gtctaaaact tagtgcttcc aggtagttat agtactccaa atcaaggacc aacttaaacg     3000

ttaatttttg tgcaaaaaca aacctgaaaa atatgcttcg gaaactgtgc atagttctaa     3060

ttgtaagtca gattgtatat tcaaattgta attaagagat ttaaatatta gaacggtatg     3120

taaggtagta taattaccac tattttaaat aattcagtta aacactgctg caatatttca     3180

gtgttgtgct tgaaaatatg tacagttttt ttccaatatt aataccttat gttgtcctta     3240

aatatttcta aaagcgcctt tatttcagca ttaccttttt ttcatcacta tcttttataa     3300

aacattaata taagtcgtta cttttagaaa ctaaaggaaa taatagctgg aaaaccctct     3360

gtagtttaaa atcagtcatt aaactcacaa tagggtaagt aaatatagcc acctgttaac     3420

atgtaaataa gcataatttg ttccaaagat ggaatattga aacttagttc atgtctgctg     3480

taaaatatta tttaaatgct gctgggcatt tcacttaaag aacttaatgt caacagctac     3540

aacaaagacc aaatctgaac tgctaatgtg gctgctttgt agggaatgga ctaatatcag     3600

tgtgttagat cttaaggtat cagtatttca gaatcctgcg acgattttat ttctaaattc     3660

atgtactgta tgtccataag tgaaaataaa atgtcatatt cttttct                   3707


<210>  618
<211>  2288
<212>  DNA
<213>  homo sapiens

<400>  618
tcgtcggagc gcggctcagc ggcgcggcgg agactcggca cggcggcggc caggcgcagg       60

cgggcgggcg gagcagcgga cggcgccgag gccgccccac gcgccgggct cgcggcggcg      120

cagcgcgccg gagtggtcgg ggcccgcggc cgctcgcgcc tctcgatggg cagctcgcac      180

ttgctcaaca agggcctgcc gcttggcgtc cgacctccga tcatgaacgg gcccctgcac      240

ccgcggcccc tggtggcatt gctggatggc cgggactgca cagtggagat gcccatcctg      300

aaggacgtgg ccactgtggc cttctgcgac gcgcagtcca cgcaggagat ccatgagaag      360

gtcctgaacg aggctgtggg ggccctgatg taccacacca tcactctcac cagggaggac      420

ctggagaagt tcaaagccct ccgcatcatc gtccggattg gcagtggttt tgacaacatc      480

gacatcaagt cggccgggga tttaggcatt gccgtctgca acgtgcccgc ggcgtctgtg      540

gaggagacgg ccgactcgac gctgtgccac atcctgaacc tgtaccggcg ggccacctgg      600

ctgcaccagg cgctgcggga gggcacacga gtccagagcg tcgagcagat ccgcgaggtg      660

gcgtccggcg ctgccaggat ccgcggggag accttgggca tcatcggact tggtcgcgtg      720

gggcaggcag tggcgctgcg ggccaaggcc ttcggcttca acgtgctctt ctacgaccct      780

tacttgtcgg atggcgtgga gcgggcgctg gggctgcagc gtgtcagcac cctgcaggac      840

ctgctcttcc acagcgactg cgtgaccctg cactgcggcc tcaacgagca caaccaccac      900

ctcatcaacg acttcaccgt caagcagatg agacaagggg ccttcctggt gaacacagcc      960

cggggtggcc tggtggatga gaaggcgctg gcccaggccc tgaaggaggg ccggatccgc     1020

ggcgcggccc tggatgtgca cgagtcggaa cccttcagct ttagccaggg ccctctgaag     1080

gatgcaccca acctcatctg caccccccat gctgcatggt acagcgagca ggcatccatc     1140

gagatgcgag aggaggcggc acgggagatc cgcagagcca tcacaggccg gatcccagac     1200

agcctgaaga actgtgtcaa caaggaccat ctgacagccg ccacccactg ggccagcatg     1260

gaccccgccg tcgtgcaccc tgagctcaat ggggctgcct ataggtaccc tccgggcgtg     1320

gtgggcgtgg cccccactgg catcccagct gctgtggaag gtatcgtccc cagcgccatg     1380

tccctgtccc acggcctgcc ccctgtggcc cacccgcccc acgccccttc tcctggccaa     1440

accgtcaagc ccgaggcgga tagagaccac gccagtgacc agttgtagcc cgggaggagc     1500

tctccagcct cggcgcctgg gcagagggcc cggaaaccct cggaccagag tgtgtggagg     1560

aggcatctgt gtggtggccc tggcactgca gagactggtc cgggctgtca ggaggcggga     1620

gggggcagcg ctgggcctcg tgtcgcttgt cgtcgtccgt cctgtgggcg ctctgccctg     1680

tgtccttcgc gttcctcgtt aagcagaaga agtcagtagt tattctccca tgaacgttct     1740

tgtctgtgta cagtttttag aacattacaa aggatctgtt tgcttagctg tcaacaaaaa     1800

gaaaacctga aggagcattt ggaagtcaat ttgaggtttt tttttttgtt tttttttttt     1860

ttgtatgttg gaacgtgccc cagaatgagg cagttggcaa acttctcagg acaatgaatc     1920

cttcccgttt ttctttttat gccacacagt gcattgtttt ttctacctgc ttgtcttatt     1980

tttagaataa tttagaaaaa caaaacaaag gctgtttttc ctaattttgg catgaacccc     2040

cccttgttcc aaatgaagac ggcatcacga agcagctcca aaaggaaaag cttgggcggt     2100

gcccagcgtg cccgctgccc atcgacgtct gtcctgggga cgtggagggt ggcagcgtcc     2160

ccgcctgcac cagtgccgtc ctgctgatgt ggtaggctag caatattttg gttaaaatca     2220

tgtttgtgac tgtaaccatt tgtatgaatt attttaaaga aataaaaatc ctggaaagag     2280

ccagcgtg                                                              2288


<210>  619
<211>  4583
<212>  DNA
<213>  homo sapiens

<400>  619
gcggccgccc cggcggctcc tggaaccccg gttcgcggcg atgccagcca ccccagcgaa       60

gccgccgcag ttcagtgctt ggataatttg aaagtacaat agttggtttc cctgtccacc      120

cgccccactt cgcttgccat cacagcacgc ctatcggatg tgagaggaga agtcccgctg      180

ctcgggcact gtctatatac gcctaacacc tacatatatt ttaaaaacat taaatataat      240

taacaatcaa aagaaagagg agaaaggaag ggaagcatta ctgggttact atgcacttgc      300

gactgatttc ttggcttttt atcattttga actttatgga atacatcggc agccaaaacg      360

cctcccgggg aaggcgccag cgaagaatgc atcctaacgt tagtcaaggc tgccaaggag      420

gctgtgcaac atgctcagat tacaatggat gtttgtcatg taagcccaga ctattttttg      480

ctctggaaag aattggcatg aagcagattg gagtatgtct ctcttcatgt ccaagtggat      540

attatggaac tcgatatcca gatataaata agtgtacaaa atgcaaagct gactgtgata      600

cctgtttcaa caaaaatttc tgcacaaaat gtaaaagtgg attttactta caccttggaa      660

agtgccttga caattgccca gaagggttgg aagccaacaa ccatactatg gagtgtgtca      720

gtattgtgca ctgtgaggtc agtgaatgga atccttggag tccatgcacg aagaagggaa      780

aaacatgtgg cttcaaaaga gggactgaaa cacgggtccg agaaataata cagcatcctt      840

cagcaaaggg taacctgtgt cccccaacaa atgagacaag aaagtgtaca gtgcaaagga      900

agaagtgtca gaagggagaa cgaggaaaaa aaggaaggga gaggaaaaga aaaaaaccta      960

ataaaggaga aagtaaagaa gcaatacctg acagcaaaag tctggaatcc agcaaagaaa     1020

tcccagagca acgagaaaac aaacagcagc agaagaagcg aaaagtccaa gataaacaga     1080

aatcggtatc agtcagcact gtacactaga gggttccatg agattattgt agactcatga     1140

tgctgctatc tcaaccagat gcccaggaca ggtgctctag ccattaggac cacaaatgga     1200

catgtcagtt attgctctgt ctaaacaaca ttcccagtag ttgctatatt cttcatacaa     1260

gcatagttaa caacaaagag ccaaaagatc aaagaaggga tactttcaga tggttgtctt     1320

gtgtgcttct ctgcattttt aaaagacaag acattcttgt acatattatc aataggctat     1380

aagatgtaac aacgaaatga tgacatctgg agaagaaaca tcttttcctt ataaaaatgt     1440

gttttcaagc tgttgtttta agaagcaaaa gatagttctg caaattcaaa gatacagtat     1500

cccttcaaaa caaataggag ttcagggaag agaaacatcc ttcaaaggac agtgttgttt     1560

tgaccgggag atctagagag tgctcagaat tagggcctgg catttggaat cacaggattt     1620

atcatcacag aaacaactgt tttaagatta gttccatcac tctcatcctg tatttttata     1680

agaaacacaa gagtgcatac cagaattgaa tataccatat gggattggag aaagacaaat     1740

gtggaagaaa tcatagagct ggagactact tttgtgcttt acaaaactgt gaaggattgt     1800

ggtcacctgg aacaggtctc caatctatgt tagcactatg tggctcagcc tctgttaccc     1860

cttggattat atatcaacct gtaaacatgt gcctgtaact tacttccaaa aacaaaatca     1920

tacttattag aagaaaattc tgattttata gaaaaaaaat agagcaagga gaatataaca     1980

tgtttgcaaa gtcatgtgtt ttctttctca atgagggaaa aacaatttta ttacctgctt     2040

aatggtccac ctggaactaa aagggatact attttctaac aaggtatatc tagtagggga     2100

gaaagccacc acaataaata tatttgttaa tagtttttca agttttgttc actctgtttt     2160

attgtttgtt ttattgagaa attcttactc ttagagactc atgaattaag aaagagaatt     2220

ctgctaactc agagaacctg gttcctatgt aattcagaat atattacatt tctcagtaat     2280

atttgttttt tgaatccacc tttatctgag ccaatggaga tttacttata gcgtattagg     2340

agatatttat tccattttct tattttaatc aacattctaa ttatagacac atgggcctcc     2400

ctagctgatt tcactgctcc cccttcattg cttagaaatg ggcatcattt cttgtatgtc     2460

agatccccct gcatcttcaa catttagtct tttcttctcc atattttcta tctgtggatc     2520

tctttagggg attgaagtca ccctagctga aggcctcacc agtgtttcac agaggacaca     2580

gcccacccct tgcaggagga ggtatctctg agtgtgcagc acagaatcgc atgacccacc     2640

ttaaccttcc tgttgtcatg gaaggatgca cggctgctct gtccactgtg attcctagcc     2700

ctctcaagat cactgctttc tgaagaattt gcaatgactc tggcttctgg ctgcttatct     2760

ctggacaccc gttctccacc agttgtacag ttcatgtaat ctacttggct taattgattt     2820

tccacttctc tcttcctctt ctaagatata aacattttaa atgatttatt cctgtttctt     2880

attctggtgt ttctttcctt gtccctatga gataagtgtc tcaactcact aaatctattc     2940

ccaatgtata aaataattct aattccattt tcagctaaaa catatattac caagaagaaa     3000

caaactttat cctacagaat gatgttaggt agaaatatgt ccccaggttt gagacctttc     3060

ggatgatttc atataccatc tttcttctga gtgttaccca gtcaagtata agtagccaaa     3120

ttatttttgc acatctttct gtttctcatg tcttcattta ttcaacaagc acttactggg     3180

aaggtctaca cctgcatagg caatgctgga aaaagggtta agtaaaccag gacatgacaa     3240

tggtggcaaa tgactatcag gtcttcccat gtgtttgact caaacttatt accctatggt     3300

ccttctgaca atggcagaag gtctgaatcc ttgatgctaa acttatataa aagtagaatt     3360

attacaaagg aaaaagaaat aaaaactaac attcattttc atatgttgga tgaaatataa     3420

atgaagaaaa agataacatc aattttaact gtaattctcc atccaccagt aacagatcct     3480

taagacaata gaatcataca gtattcaaac cagcagcctt ctcaaatttg agcaaaaact     3540

ctatcaacct ctggtaaagt tcctacacta gtcacagaag gtgttaactt tctactctga     3600

ttctgtctcc ataatggggt aaactgttga tagtttaccc catcaacaga tggtcggtaa     3660

attattgatt cgaagaatcg agagagtgca gcaacataaa tctgttaatg tctgatcaag     3720

ctcctgccct gttctccgaa ttcagcttca taattaaggg aaggcctgtt ttctatcctc     3780

agatttaggt tctagtagca gttgtgtaac cactagtgag tcacttaact cctctgggtc     3840

cccatttctc atgtgcaaca agaaagaggg gaactggaga tgatcactct agttccagac     3900

aagggaacat ttcacacttt gtttacttca gggtgatgtc cctgagtcct cattagtgac     3960

tgcgtccttt ggaagttatc ccaaccctgc ttttctcaaa agtgaaaatg tataggctct     4020

cagaggagac agatttaact ctgcttctct aatgttattg aattaaaagc tgttcacatt     4080

agtggttatt aaatattgaa ataacactgg gaagaaaaag catatataaa tacagctaaa     4140

aacaagaata gatattcatt ctcacaaagg gagacagcaa agaaaatgga aagtgcactg     4200

gtgctagcgt tagacagctt gtgttaatgt ctcaattctg ctactaactg gttgcagctt     4260

gtgtgacctt gggcacattg tatgatctcg cagaatatca tcccaaatct gcaaaatgga     4320

attggcatca tctcttttgc aagattgtta tgagaattaa aaggttcttc attcaatata     4380

ataataaata ttttgtatat aaatgaatat caattaaaag ttatgactaa ttccacaagt     4440

caaacatata aattttattt cttgattcat gatatgtgat agtattcata aaaatgtaca     4500

tgcatgataa tttcaaggaa taagtatata tgtgagaatc atggaaatga aattaataat     4560

attaactagt aattaaattg taa                                             4583


<210>  620
<211>  1249
<212>  DNA
<213>  homo sapiens

<400>  620
gagctgtgct tggggcgggg cctggcgtgt attcgaaagg aaggcgccgg ctgcgggaag       60

atggcggctc agccgctgcg gcatcgctca cgttgtgcaa cgccgccccg gggggacttt      120

tgtggtggca ctgagagggc gattgaccaa gcttctttta cgacctccat ggagtgggat      180

acgcaggtgg tgaaggggtc ctcgccgctc ggccccgcag ggctgggggc tgaggagcca      240

gccgccggcc cgcagctgcc gtcttggctg cagcctgaga ggtgcgctgt gttccagtgc      300

gcacagtgtc acgcagtgct cgccgactcg gtgcacctcg cctgggacct gtcgcggtcc      360

ctcggggccg tggtcttctc cagagttaca aataacgtcg ttttggaagc gcccttccta      420

gttggcattg aaggttcact caaaggcagt acttacaacc ttttattctg tggttcttgt      480

gggattcccg ttggtttcca tctgtattct acccatgctg ccctggctgc cttgagaggt      540

cacttctgcc tttccagtga caaaatggtg tgctatctct taaaaacaaa agccatagta      600

aatgcatcag agatggatat tcaaaatgtt cctctatcag aaaagattgc agagctgaaa      660

gagaagatag tgctaacgca caatcgctta aaatcactaa tgaagattct gagtgaagtg      720

actcctgacc agtccaagcc agaaaactga tcctgtacca aagcttgagt gtcaggttca      780

ggctttattg ctgtcttcaa caacaggtgc tgcttagtca tttcttgaaa aagattggct      840

tcaagaatgg aggggaaatg cagtttctat ttacctttag gctgattttc caaattattt      900

gtgaagctgt ttttagaaga tgagagacta aggattcttc tcttttatag ctatttgcct      960

taagaactta ctttagattc ttattgaatt cataatactt atctctgaaa atgtctttga     1020

ctgtaaattt aggaattaag atgcagagtc ccatgtgtcc tctgatctaa agttgcatgg     1080

ttggtctgaa aatagagttg ggcttaatgt tgacttctat tactcctgca tggagcagtt     1140

gttatgaata ctaatacatc actttttaac ttctgtaaaa tacagatcat aatattctat     1200

aggtaatgtt taataaattg cctgaataat atacaaaaaa aaaaaaaaa                 1249


<210>  621
<211>  1212
<212>  DNA
<213>  homo sapiens

<400>  621
tgcttccccg ccggccgccg ccctcctccc cgggagagag cgaggcgcgc gggtccctct       60

gcgccacccc cgcccccgcc ccttccgagc aaacttttgg cacccaccgc agcccagcgc      120

gcgttcgtgc tccgcagggc gcgcctctct ccgccaatgc caggcgcgcg ggggagccat      180

taggaggcga ggagagagga gggcgcagct cccgcccagc ccagccctgc ccagccctgc      240

ccggaggcag acgcgccgga accgggacgc gataaatatg cagagcggag gcttcgcgca      300

gcagagcccg cgcgccgccc gctccgggtg ctgaatccag gcgtggggac acgagccagg      360

cgccgccgcc ggagccagcg gagccggggc cagagccgga gcgcgtccgc gtccacgcag      420

ccgccggccg gccagcaccc agggccctgc atgccaggtc gttggaggtg gcagcgagac      480

atgcacccgg cccggaagct cctcagcctc ctcttcctca tcctgatggg cactgaactc      540

actcaagtgc tgcccaccaa ccctgaggag agctggcagg tgtacagctc tgcccaggac      600

agcgagggca ggtgtatctg cacagtggtc gctccacagc agaccatgtg ttcacgggat      660

gcccgcacaa aacagctgag gcagctactg gagaaggtgc agaacatgtc tcaatccata      720

gaggtcttgg acaggcggac ccagagagac ttgcagtacg tggagaagat ggagaaccaa      780

atgaaaggac tggagtccaa gttcaaacag gtggaggaga gtcataagca acacctggcc      840

aggcagttta agggctaact taaaagagtt ttttcaatgc tgcagtgact gaagaagcag      900

tccactccca tgtaaccatg aaagagagcc agagagcttt ttgcaccatg catttttact      960

attattttcc aatacttagc accatttcac taaggaacct tgaatacaac caggatcctc     1020

ctttgcatgc gactgtagct gcatttcatg aatagtttga acccttgtca atgcattttt     1080

tgaaaaagaa agaaaaaaaa aacttcgtgt atgtgactca aagcatgtaa ccttaagatg     1140

ttgcattcta aactgacaat aaagaccttt cccaaataaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aa                                                         1212


<210>  622
<211>  2879
<212>  DNA
<213>  homo sapiens

<400>  622
atcctgtccc agcctgcttc cccgccggcc gccgccctcc tccccgggag agagcgaggc       60

gcgcgggtcc ctctgcgcca cccccgcccc cgccccttcc gagcaaactt ttggcaccca      120

ccgcagccca gcgcgcgttc gtgctccgca gggcgcgcct ctctccgcca atgccaggcg      180

cgcgggggag ccattaggag gcgaggagag aggagggcgc agctcccgcc cagcccagcc      240

ctgcccagcc ctgcccggag gcagacgcgc cggaaccggg acgcgataaa tatgcagagc      300

ggaggcttcg cgcagcagag cccgcgcgcc gcccgctccg ggtgctgaat ccaggcgtgg      360

ggacacgagc caggcgccgc cgccggagcc agcggagccg gggccagagc cggagcgcgt      420

ccgcgtccac gcagccgccg gccggccagc acccagggcc ctgcatgcca ggtcgttgga      480

ggtggcagcg agacatgcac ccggcccgga agctcctcag cctcctcttc ctcatcctga      540

tgggcactga actcactcaa gtgctgccca ccaaccctga ggagagctgg caggtgtaca      600

gctctgccca ggacagcgag ggcaggtgta tctgcacagt ggtcgctcca cagcagacca      660

tgtgttcacg ggatgcccgc acaaaacagc tgaggcagct actggagaag gtgcagaaca      720

tgtctcaatc catagaggtc ttggacaggc ggacccagag agacttgcag tacgtggaga      780

agatggagaa ccaaatgaaa ggactggagt ccaagttcaa acaggtggag gagagtcata      840

agcaacacct ggccaggcag tttaaggcga taaaagcgaa aatggatgaa cttaggcctt      900

tgatacctgt gttggaagag tacaaggccg atgccaaatt ggtattgcag tttaaagagg      960

aggtccagaa tctgacgtca gtgcttaacg agctgcaaga ggaaattggc gcctatgact     1020

acgatgaact tcagagcaga gtgtccaatc ttgaagaaag gctccgtgca tgcatgcaaa     1080

aactagcttg cgggaagttg acgggcatca gtgaccccgt gactgtcaag acctccggct     1140

cgaggttcgg atcctggatg acagaccctc tcgcccctga aggcgataac cgggtgtggt     1200

acatggacgg ctatcacaac aaccgcttcg tacgtgagta caagtccatg gttgacttca     1260

tgaacacgga caatttcacc tcccaccgtc tcccccaccc ctggtcgggc acggggcagg     1320

tggtctacaa cggttctatc tacttcaaca agttccagag ccacatcatc atcaggtttg     1380

acctgaagac agagaccatc ctcaagaccc gcagcctgga ctatgccggt tacaacaaca     1440

tgtaccacta cgcctggggt ggccactcgg acatcgacct catggtggac gagagcgggc     1500

tgtgggccgt gtacgccacc aaccagaacg ctggcaacat cgtggtcagt aggctggacc     1560

ccgtgtccct gcagaccctg cagacctgga acacgagcta ccccaagcgc agcgccgggg     1620

aggccttcat catctgcggc acgctgtacg tcaccaacgg ctactcaggg ggtaccaagg     1680

tccactatgc ataccagacc aatgcctcca cctatgaata catcgacatc ccattccaga     1740

acaaatactc ccacatctcc atgctggact acaaccccaa ggaccgggcc ctgtatgcct     1800

ggaacaacgg ccaccagatc ctctacaacg tgaccctctt ccacgtcatc cgctccgacg     1860

agttgtagct ccctcctcct ggaagccaag ggcccacgtc ctcaccacaa agggactcct     1920

gtgaaactgc tgccaaaaag ataccaataa cactaacaat accgatcttg aaaaatcatc     1980

agcagtgcgg attctgacat cgagggatgg cattacctcc gtgtttctcc ctttcgagcc     2040

ggcgggccac agacgtcgga agaaactccc gtatttgcag ctggaactgc agcccacggc     2100

gccccggttt tcctccccgc cctgtccctc tctggtcaaa caacatacta aagaggcgag     2160

gcaatgactg ttggccagtt ctcaccgggg aaaaacccac tgttaggatg gcatgaacat     2220

ttccttagat cgtggtcagc tccgaggaat gtggcgtcca ggctctttga gagccatggg     2280

ctgcacccgg ccgtaggcta gtgtaactcg catcccattg cagtgccgtt tcttgactgt     2340

gttgctgtct cttagattaa ccgtgctgag gctccacata gctcctggac ctgtgtctag     2400

tacatactga agcgatggtc agagtgtgta gagtgaagtt gctgtgccca cattgtttga     2460

actcgcgtac cccgtagata cattgtgcaa cgttcttctg ttattccctt gaggtggtaa     2520

cttcgtatgt tcagtttatg cgatgattgt tgtaaatgca atgccgtagt ttggattaat     2580

aagtggatgg tttttgtttc taaaaagaaa aaaaaaatca gtgttcaccc ttatagagac     2640

atagtcaagt tcatgttgat aataatcaaa ggaattactc tcttcttgtt aaattagcta     2700

aatcatgtaa ccgcagatag gaagggctcg cctggggaaa ctctggtttc cgatgggaca     2760

ggaaagtcat acgggcaaca gtatgcggaa agtacgtttt ttaagtaaaa aacaaaggca     2820

aactttgtac tatccagtta tctaaggaac aataaaaaca ttaggagatc ttttaaaaa      2879


<210>  623
<211>  6308
<212>  DNA
<213>  homo sapiens

<400>  623
gctcctcgcc tggccgtgat atcaatggcg caggcttcac ttctgctgtg gcggtgactg       60

aggcctttct ggtgacctca gcccaacaca ggccgtctcc ggagcttccc ggtagtggcc      120

ccggattccc acggtctttg tcattggctg tcagctagca ggcctggccg ctcccgtgcg      180

gagagaccat ctcttcaggg caatgtccag gccgagcagc gtctccccgc ggcagccggc      240

tcctggcggt ggcggaggcg gcggcccctc gccttgtggc cctgggggcg gcggccgggc      300

caaggggctg aaggacattc gcattgatga ggaggtgaag atcgcagtca atatcgcgct      360

ggagcgcttc cgatacgggg accagagaga aatggaattt ccttcttctt tgaccagtac      420

tgaaagagcc tttattcatc gactcagtca gtctcttggt ttggtctcta aaagtaaagg      480

aaagggagca aatagatacc taactgtgaa gaagaaagat ggatcagaaa cagctcatgc      540

aatgatgacc tgtaatttga ctcataatac aaaacatgct gttaggagcc taattcaaag      600

atttcctgtc accaataaag agcgtacaga acttctgcct aaaacagaaa gaggaaatgt      660

gtttgcagtt gaagctgaaa accgggaaat gagcaagaca agtgggcgac tcaacaatgg      720

catacctcag attccagtga aaagaggaga atccgaattt gattctttta ggcagtcttt      780

accagtgttt gagaaacagg aagaaattgt taaaataatt aaggaaaata aagtagtttt      840

gattgtagga gaaactgggt ctggaaagac cacacagatt cctcagttcc ttttagatga      900

ttgctttaaa aatggtatcc cctgccgtat attttgtact caaccaagac gattggcagc      960

tatcgctgtg gctgaaagag ttgccgcaga gagacgggaa aggattggtc aaacaattgg     1020

ttatcagatc cgattagaaa gcagggtttc tccaaagaca cttctgacat tttgtactaa     1080

tggggtattg cttcgtacat tgatggcagg agatagtacg ttgtcgactg tgacacatgt     1140

tatcgtggat gaagtgcatg aaagggatcg atttagtgat tttttactta caaagttaag     1200

agatttgttg caaaagcacc caactttgaa actaattctt tctagtgctg ccttggatgt     1260

aaatctcttt ataagatatt ttggaagttg tccagtgata tatatacagg gaagaccatt     1320

tgaagtaaaa gaaatgtttc tggaagatat tttaagaaca actggatata caaacaaaga     1380

aatgttaaaa tataaaaagg aaaaacagca agaagagaaa caacaaacca cacttacaga     1440

atggtactca gctcaagaaa atagtttcaa gcctgaatct cagaggcaga gaactgttct     1500

aaatgtgact gatgagtatg acttactgga tgatggtggt gatgctgtct tcagtcagct     1560

gactgaaaaa gatgtgaatt gccttgaacc atggttaata aaggaaatgg atgcttgcct     1620

ttctgatata tggctacata aagatattga tgcctttgct caggtctttc atctcatttt     1680

aactgaaaat gttagtgttg attacagaca tagtgaaacc agtgcaacag ctctgatggt     1740

tgctgcagga cgtggctttg caagtcaagt agaacagtta atcagtatgg gagccaatgt     1800

ccatagtaaa gcatcaaatg gctggatggc attggattgg gctaaacact ttgggcagac     1860

tgaaattgtg gatcttctag aatcttacag tgctacactg gaatttggaa atctagatga     1920

aagttctctg gttcaaacaa atggaagtga cctcagtgct gaagacagag agctcctgaa     1980

agcttatcat catagtttcg atgatgaaaa agtagacttg gatttgatca tgcatcttct     2040

atacaatatc tgccatagtt gtgatgctgg tgcagtacta atttttctgc ctggatatga     2100

cgaaattgtt ggactgagag atcgcatcct gtttgatgac aagcggtttg ctgacagtac     2160

acatagatac caagtcttta tgcttcattc aaatatgcaa acatccgatc aaaagaaagt     2220

attaaaaaac ccacctgcag gtgttcgaaa aataattctt tccaccaata ttgctgaaac     2280

cagcatcaca gtcaatgatg ttgtctttgt tattgattct ggtaaggtga aagagaaatc     2340

ctttgatgct ctgaattttg ttacaatgtt aaaaatggta tggatttcca aagctagtgc     2400

catacagcgg aaaggcaggg cagggcgatg tagacctgga atttgttttc gtctgttcag     2460

tagactccga ttccagaata tgttggaatt tcagactccg gaacttttga gaatgccatt     2520

acaggaactt tgcttacata ccaagctgtt agccccagtt aattgtccca ttgctgattt     2580

tcttatgaaa gctcctgaac ctccaccagc tttaattgta agaaatgctg tacaaatgct     2640

taagacaata gatgcaatgg atacatggga agatctgact gaacttgggt atcatttggc     2700

tgacttgcca gtagaaccac atcttggtaa aatggtcttg tgtgctgttg ttttaaagtg     2760

tctggacccc atccttacaa ttgcttgcac actagcttat cgagatcctt ttgtactacc     2820

tactcaggcc tctcaaaaac gtgcagctat gctttgtagg aaacgtttta ctgcaggagc     2880

tttcagtgac catatggcac ttctcagagc attccaggcc tggcaaaaag cacgaagtga     2940

tgggtgggag cgagcctttt gtgaaaagaa ttttctttca caggctacta tggaaataat     3000

cataggcatg agaacacagt tgcttggtca acttagagca tcaggttttg ttagagcacg     3060

aggtggtggt gacattcggg acgttaacac aaactctgag aattgggctg tcgttaaagc     3120

tgcattggtg gcaggcatgt atcctaattt agtccacgtg gacagagaga atctagtgtt     3180

gacagggcca aaggagaaaa aagtacgatt tcatcctgct tcagttctca gtcagcctca     3240

atataaaaag attcctccag ccaatggtca agctgcagca attaaggcac tgcccacaga     3300

ttggcttatt tatgatgaaa tgaccagagc ccatagaata gctaatatta gatgttgttc     3360

agcagtgacg cctgtcacta tattggtatt ctgtggacca gctagattgg caagtaatgc     3420

tcttcaggaa ccttcatcct ttagagtgga tggcattccc aatgacagta gtgatagtga     3480

aatggaggac aaaactacag ctaatttggc agccttgaaa cttgatgagt ggctccattt     3540

cacactggag ccagaggcag ctagtttatt gctgcagctc agacagaagt ggcatagctt     3600

atttttacgc cgaatgagag ctccatctaa accttggtct caagttgatg aagctaccat     3660

aagagcaatt atagctgttt taagcactga agaacagtct gcaggtttac aacaaccatc     3720

tgggattggc caaaggccaa ggcctatgtc ttcagaagag cttcctttgg cctcatcttg     3780

gaggtcaaat aatagtagga aaagttcagc agatactgaa ttttctgatg agtgtactac     3840

tgcagaaaga gtactgatga aatctccatc tccagcatta cacccacctc agaagtacaa     3900

agatagagga attttacatc ctaaacgagg tactgaggac cgatcagatc agtcttctct     3960

gaaatctaca gacagcagta gttacccaag tccttgtgct agtccttctc ctccatcctc     4020

aggaaagggc tcaaaatctc cttcgccaag accaaacatg cctgttcgat acttcataat     4080

gaagagtagc aatttgagaa accttgaaat ttctcaacag aagggtatct ggtctacaac     4140

tcctagtaat gaacggaagc taaatcgagc cttttgggaa agcagcatag tttacttggt     4200

attttctgtt caaggatctg gacatttcca gggattttct aggatgtctt ctgagattgg     4260

aagggaaaag agtcaggact ggggctctgc tggactagga ggagtattta aggtggagtg     4320

gatacgaaaa gaaagccttc cctttcaatt tgcacaccat ttactcaatc catggaatga     4380

caacaagaaa gtgcagataa gcagggatgg gcaggaacta gaacctctgg ttggtgaaca     4440

gttgctccag ttatgggaac gtcttccctt gggagaaaaa aacacaactg attgacactc     4500

agaactctta gctgtggaag aacatcatgc ctatttataa ccactgaatg cactgacttt     4560

caaaaactga ggtggggtgt gtgttacgaa tgggcttttt aacactttta gagtgttgct     4620

ttagaactac catcttcata tacaggagaa aggaagcatt taaattttta tagtgattat     4680

agagaatgat tatatgatgt ttgtaatgaa taaaatagta gtttcattat ttggcacaat     4740

agcagtttat tttaaacaaa caatttgaag ttaaacattt catttttaaa aacactgaat     4800

tacagttctt attgatgact ttttaatgca gagtaagttg tttaagaaag gcctgaatat     4860

atcagaacat ctgagcacca ttttagaaga gtcaactctt aagattatca ttagaaaaca     4920

aatacgtcaa cacctatgaa aagaagcggg gaaaacaaca acaaggacaa caacaaaaaa     4980

ccagtgaaat tctacaagtg tcccttttaa aaatagtgtg tgctaactaa gggctattca     5040

ttctgccatt tttaacttga gacacattta agaataaagt tggatgttct ttttctgtga     5100

ttatgaaatg caataaaatc tgaataaagg gcaaagtttc ttcctgatca gattagatta     5160

agtgcttagt tttattccta attctgcccc ttttaacctg atgtgtacct tactctttcc     5220

tccctctctt cctcccttcc tcctctcccc gctcctttcc tgcatttctc cctccctcct     5280

tccctcgtca catctcttat atgagcacag taattatgac ctttttgttt tggctacaac     5340

ttgattgaaa caagttcaaa atttaaacaa gttcatacaa gtttttaaaa attctcaact     5400

ggtagcttgc ttgctgtgcg tcttccaaac taaagcctgc aagcgccaca attctaagtg     5460

ccgccttcca ttttttttca gtatgttttc actggcttat gttttcagat atgattttcc     5520

tttttcgcat atatggttta ataaatgggg gataattttt tttttgtaaa tccgtgcttg     5580

tgccaagtct catatttctt tgccatctca gaattatctt tttaccacca ctgtttataa     5640

aatttcctta gagacttttt gaagggaaaa tagagcaaca gggaaaaatg aaagaaatgt     5700

cttggttact gagctctaaa tagacaggtt tgatggcact tctcatgata cattttagtt     5760

attcttataa aagcaaacag gcaaacatga gtgtaaatta aagacaaaaa gaaaactctg     5820

gttttatatt tgagaacacg tgaaaaatca tgggtcaaca taaaatcttg agaaccttct     5880

actttctctg ggaaagcatt atatagtggt gcattagttt agaaagtcag ctatgatttt     5940

gcctatagtt ctagttatta gctttggggt tttcttgtac tttaagacat acctgtaaat     6000

tgaacctatt tgaattatat tccactgtat gtgtattatg gctcttttcc tattagagca     6060

acttgtgttt ccctgataat gtgtacattt tttaggcatg tacttaatag ttcacaatgt     6120

tctaaatttg gaaggactta aaaaaaaaac ttgtttaaat ttccatctgt tttgtaatat     6180

ctagctctat atgtaaatga tgggtttgtt ggtatttaaa atgaatacaa cttgaatgta     6240

attaaagtgc tgttttttgg aagcgataaa ctttaaatat acttattaaa atgaaattct     6300

attaagtt                                                              6308


<210>  624
<211>  9540
<212>  DNA
<213>  homo sapiens

<400>  624
agtgcatgaa gtatgctcag tgtgccagca agggctgata atcagcagaa ggacagggtg       60

cttcgttagt cagaagagcc agggcttccc ggctgccagg ctacagaact cgcctcgcca      120

ctcctgagac atggacaacg ccgttgacgg actggacaaa gcttctatag caaactcaga      180

tggccccaca gcaggttccc aaacacctcc cttcaaaaga aaggggaaac tatccaccat      240

tggtaaaatc tttaagcctt ggaaatggag gaaaaagaag accagcgaca aatttagaga      300

aacctcggca gtattagaaa ggaagatatc cacacgacaa agtagagagg agctgataag      360

aaggggagtg cttaaggaat tgcctgatca agatggagat gtaacagtta actttgaaaa      420

ttcaaacggg cacatgatac ccatcggaga ggaatctacc cgagaggaaa atgtagtaaa      480

gtctgaagaa ggtaatggct ctgtatctga aaaaacacca cctctggagg aacaggcaga      540

agataagaaa gagaacactg aaaaccactc tgaaacaccg gcagctcctg ctctacctcc      600

ttctgctcct cctaagccta gacccaaacc taaacccaaa aaatcacctg tgcctccgaa      660

aggggccact gctggggcca gccacaaagg tgatgaagtg cctcccatta aaaaaaatac      720

caaggctcct ggtaagcagg cccccgtccc tccacccaag ccagcaagcc gaaacacgac      780

ccgagaggct gctggctcct ctcattcaaa aaaaacaact ggctctaaag catcagcttc      840

gccatccact tcatccacct catctcgtcc caaagcttca aaggagacag tttctagcaa      900

agcagggaca gtggggacca ccaagggcaa gagaaaaact gacaagcagc caataacttc      960

tcacctgtcc tcagacacaa caacttctgg cacatccgac ctgaaaggag agcctgcaga     1020

gaccagagtg gagagtttca aactcgaaca gactgtccct ggagctgagg agcagaacac     1080

aggcaaattc aagtccatgg tccctccacc ccctgtggct ccagcacctt ctcctctggc     1140

cccccctctc cctcttgagg atcagtgcat tactgcctca gacactccag ttgtcctcgt     1200

cagcgttgga gctgacctgc ccgtctctgc cttagaccca agtcagcttc tttgggctga     1260

agagccgacg aacagaacca ctctctactc aggcactggc ttaagtgtta acagagaaaa     1320

tgcaaaatgt ttcacaacca aagaggagct ggggaagaca gtgcctcagc tactgactcc     1380

tgggctgatg ggcgaatctt cagaatcctt tagtgcctca gaagatgaag gccacaggga     1440

ataccaagcc aatgactctg actcggacgg gcctatcttg tacaccgatg atgaggacga     1500

agacgaagat gaggatggca gtggagaaag tgctttggca agtaaaatac gccggaggga     1560

tactcttgct atcaaacttg gcaacagacc atctaagaaa gaactagagg acaaaaacat     1620

cttgcagcgt acatctgaag aagagaggca ggaaatccga caacaaattg gaaccaagtt     1680

agtcaggagg ctgagccaga ggcccacaac tgaagaatta gagcaaagaa acatcctaaa     1740

acaaaagaat gaagaagagg aacaagaagc aaaaatggaa cttaaacgca gactcagcag     1800

aaagctcagc ctgagaccca cagtggcaga gctacaagct cgaaggatcc tgcgatttaa     1860

cgagtatgta gaagtcacgg attctcctga ctatgaccgc cgagcagaca agccctgggc     1920

caggttaaca cctgcagaca aggcagcaat aaggaaagaa ctaaatgaat ttaaaagcac     1980

agaaatggaa gttcatgaag agagtcgaca gtttacaagg tttcatcgtc cataacgaag     2040

agtgagacta tttggaaaca gagactgatc atctttgggg gaagccctgc ttcctgaaaa     2100

cctgatattg cactgggatt tgaatgtgtg tgtttccgtt taacttgtgg tgaaggaagt     2160

gtgtgactca gcttggctgg gaagtgctcc tcacctgtgt ggcccagatg gctccaacaa     2220

gcaaaaggaa ggatgcagtg actcttgctg cccagaatgc acagcgatgg taagagacac     2280

cgtggatatt cttcatcaga agctttaatc aaagaagatg agcagaagac aatcactggc     2340

tccctgttac cagaaagcca aattttataa tgcgggtgaa agaaaaatat agattaaaat     2400

tgctgggcac tgaaaagggg tgggagttgg aaatcagaaa gaaagagaaa tatttcatta     2460

tgttaatgaa gaaaagagaa aattgaagca taaatgtatt tttgaagtag ttattcggta     2520

gctgagaact tattaaggga tttaggaatt taacctcctg atgtggattc ctcaaagact     2580

tgatcggaga atactcttgt ttcaccatta tgttggtaca gtatagtacc attattttat     2640

gttgtgccag tgaatccagt tgccagaaat aagtctgaat gttttcatgc atctttttct     2700

taaatgcaag agcttctact gactcttaac aagcatgctt acccaaattt tgttgcatgc     2760

ttttaagtag cattagctat gcacacttga catttttaaa tatccctttc ctagtgtacc     2820

agccttcaca ggataagagg actgggaata aagtcagatg taatgtgacc ctagaaaact     2880

gtagcaagct tcagaaataa atcttttgat ctttccctat cttgattaga tccaaagtca     2940

aagcaaccat acttcaccta gagaagacag tattggcaat catgacacct gtaataaaaa     3000

cttgaatcca aagtcaaaac ttaagcaaga tacaaatgtg ctgcctgcag ttagtcctgc     3060

atgggaataa ggactagtta tttttttagt gctgcatttt tttaaagttg gattgctgct     3120

atttaaaaaa aaaaaaagga cacagatcaa aaaaacaccc aaaggcttaa cagaacatgg     3180

aaagttccca ctaagttgtg tgtgaggaaa tcctcatctt gtattttaag aatctgcaga     3240

tggcatccat agatacagta cagtatttac tgtcaatgca aaagaatcag tgaggttaaa     3300

gtagtggaag ttttccctat gagcctacag tctgtattgt ttacattaag aaactctcta     3360

ttattgtgtt gctattttcc atggagtcac aggcacacta tgacttctgc tcccaaatac     3420

atatgaccat atgtaaatac caccttgcat ttcattgttc ttcacaagtg ctttgtgccc     3480

ctttaattaa aaacacatga aatgaataac aaaacaagac ccaaatagag tttattttat     3540

tctcagagtt tggactacaa ttttctaaga tgtttctggt tcaagactgt cattttctat     3600

ttcaaccgaa aagtaagcat ttaacccggt gaataaatgt agatcctgcc attcattggt     3660

attttaaaga accacttgaa atcggatcat tttatttaaa aataaaaaat gttaatgcca     3720

gttggcctac tataaaaagc caggaccatg ttagaattag gaaaagtaac cagcattact     3780

gcacctcttg ttagactctg tgcattaata aaacacacct agagtctgtt gtcatttcac     3840

taataggata agacaaattt tttgctttga aaaaattttt ctgcatgccc aggtgtctgt     3900

ctctggctga ggttttgtct attttacagt gtttcaatcc agccataaaa attaacttgt     3960

gatttttttt ttcccaaagt catgcttttc cttaattata tttttatttt attattttag     4020

tgtcttgaga aaaataccaa gagatataat gtttctttta attgtctatg cttaatcatc     4080

tttaaacact ttttaaattt ctaaccacaa gacctctcta taatggtaaa tgtaagacat     4140

caccatttta tcactcaaag tatgttattg aaagtttcta tttggttgat aaaaggaaca     4200

attttttccc acttttgatg cctgtgatgc aattttttat tgcctacaat gagatacact     4260

tagtacaaaa aatgaaaatc tggtatttca aaattgcatt tcttgtataa taggtcagat     4320

ttattaacta ctcatacttt ttctttacac taatcgatac atttagaaaa aattttctaa     4380

gttagagaca agtttaaaag taaaaaaaaa aaaaaattag ccactgctag tctactgttt     4440

aggtaatcgg aatcaccaat tattttatta gaatgatggc ttgagtaaaa agctgtggaa     4500

agaattaaag gattatgagc taagctgtat tttgcagaat atggttctat tttagtagag     4560

cagagatgag acatatcccc accggccacc cagccagagg tctcctacct gggggcccta     4620

aagggatgca gaggtctggc ccaccctccg tgcataggca cctctgtcca ccaccagcgt     4680

ttcagcaatc caaccagtaa gcatatgctg tataggaaaa ataaaagtgt gtgggaattg     4740

gatttctttt gttgtaacac aattccaggt ttttggctat ttaaagtttg acattaggct     4800

gacatcgagg aagtaagtgg gttttcctga gttcccaaga tatgattaag gaagaaaaca     4860

aacccatctc caggaagatc ccaggcagga aagaactaga cagatgtaga aaccaaagtg     4920

accattttag tttttttatt ggagaataaa acattaatat tagggtatta agaagatgct     4980

cagcaagctt gatcagaatc ttcatggtca ttaccaatca gtctgacaaa atagttctct     5040

ggtagtcagc attcatttaa ggcagcttgc ctgataattt cctgtgttat gtgaagtgtc     5100

ttgcactttc acatgttagc tataattcct taaattactt aactgaaatc tgtaatagag     5160

aaccattttg gcatttgaac agctatttta catggagaaa aagcaaacac atctgtttgc     5220

tttacccaga aaaactgact ttctggtttc atcttcatat tgtttagtag cataatgaga     5280

gtagtccttt atctttctct aatgttagta aatatattct gttagtagga agttctgaaa     5340

ttgaagggaa aatatattta aggaaataaa ggaattcaat acacccttca aaagtcacca     5400

aatactgaaa ataagagatg agtccttaaa acctgagtca aaaaaggtcc agttttacag     5460

cctgcaatta attcagggct gcgttggcat taaaaaagaa aatatatata tatatatata     5520

tatatatata tatatatata tatatgtata ttatatatac agtagcttac acttaaaaga     5580

ggaaaaattt gcattaacat tgcatattct gatatgtacc atattaacac ataacaggca     5640

ttttatttat gcttcataga atcagacaga cacaactttc aaaaatctta ctgtattcac     5700

aatagaaaag ggtagtcttg tctaccacag aggagtatgt ccacacttaa taatgaaaac     5760

tttcttcctt tcctgcccaa aaatttcttc agtctgttat tatttttaag tgccccttgc     5820

tgcaaatttc aaacagagca agaaatcttc ctcagagtag gtggtatgaa attaaactag     5880

tacaatatat atgaattcat gtcatttacc cctgagtatg gtagaattgt taaagcattc     5940

ttaaattcca attatatgaa gcctatcatt actaggaaaa gtatattctt tgggataaga     6000

attaatttct tcacactatt agagcatgtt gtgagtagta aggaactact tagatgcaat     6060

ttatttacag aattgtccct tgacctcttg aaatggctag atctttcact actgtgtagg     6120

tagtctctac ttactggtag gatagattac attgctttac tggacaaagc agaatgaact     6180

tatataacta aaatatgtcc tatattggct gggtgcggtg gcttacacct gtaataccag     6240

cactttggga ggccaaggtg ggtggatcag ttgaggtcag gagttcgaga ccagcctggc     6300

caacatggtg aaaccctgtc tctactgaaa atacaaaaaa aaaaaagtat ctgggcatgg     6360

tggcttgtgc ctgtaatccc agctacttgg gaggctgagg cagggaaatc gcttaaaccc     6420

gggaggtgga ggttgcagtg ggcccagatc gtgccactcc actccagcct gggagacaga     6480

gcaagactcc atctcaaaat aataataata gtaataatga ataaaataaa ataaaatatg     6540

tcctccaggg aaaagcaatg acagagtaat caccaaatta ataggaacat ctttctagag     6600

aaagtacatg cccagttagt tcaaacccag gtttcaaaga agtagcactg ggctctactg     6660

taaaggcagg cagtgaccaa gaggtggtgg ggagagaggt agagtaccct caaatcattc     6720

ccattttcac ttccaatttc ccttttgtaa tcattaagct taagctatgt atggaaatgc     6780

aaagcaccat tagcatttct agaaagcagc tggaacctta cccaccaatg cttttttgaa     6840

gacagtatca tcccaaattt aaaaatccta ttgtatatgt tgtaaaattt ctggcaaaga     6900

aatggaggat cctgtggcag ctattcccac ctaaagccaa ccctataagg atgggtcatt     6960

ttttagccat gctaggattt actgcacaca caaaaaatgt catttagctt gtcacattgc     7020

tagcacagct gcacatatga gcaaagcact gttggtctgt gtttctcagt gggggtactc     7080

ttggcatttg gagctggata ggtctttgct gtacagaatc atcccatgca ttgccagatg     7140

tttaatatcc caggcccctg ctgactaaat gtcagtagca ttctcagtca ttgtaaacac     7200

caagaataaa aagcattccc ccaggttcaa atgccctccc tgggaggttg gtatcacctc     7260

ccctgaatgc cactgtctac tgcattttga ggacacaggg agaaaaagtg cctatcctca     7320

aacattgtct ctgctgcctt gcatttcttt gggccctgaa tggtttttct cccttcattt     7380

ttcgagcctt tctctcagtg cagctgttct tcagggagga ggttactggg cagccttggc     7440

cattcagtgg gcatggggac ttggcctagt ccctatatat atatacttaa agtccctata     7500

tatacttaaa ggagagatca tacatgaaga aagctttttt tttttttttt ttttttgcct     7560

tacaactttt ctttagaacc acattattgg tcataatcct tgttactgtc atgaggattg     7620

ttgcatgggt taaacacaaa cacagactag caatgcactt gaacaaacct ggtggtcttt     7680

ggaaataaat caccattaga tttcacctgg ttatgctgca tcccataagt tccaaatgaa     7740

tcacctgctt atcctattaa cgaagcattt aattcacaca caaatgcttg aatttcccct     7800

gtataaatgt agtcatgcga ttcaactttt ctaataagat ttgtgaatgc tgcatcatga     7860

tgaaaatgtg gattaactgt gggttgcatg cctgttgttc atacttcagt gatggtcaca     7920

cacaaaacaa gatgagtttt acttaggtga aacattatta aactgtacta acaatacaga     7980

aacatattct ctttgtcgct ttttatcacc aaaactgaat ggcaaatatg tcttgacatt     8040

acttggatga actgtggcta gcaaaatgga attaacttag ccactataat tttttaaaac     8100

attaaagttt ctaaattgtt tttggggccg agtaacgcag agtcaataaa ggtggttata     8160

ttgtaagctt ttagatggtg cttaagaatt cttatctttt taaatagcag tatttttttt     8220

ttaagaataa attgtaagga gcaaataagg cagaatgcca ctctaccctc aggtcaattt     8280

tatggtatat gaaaatgcca gtaatatttg tgccacttgc caactcgggg gaggaggggc     8340

ttttccctta ctggatactt ttgttatagt ttgactatgt cattatgttg tttagagagc     8400

ctccacaatg agaagttgcc actgcagggc taactcgcct tcagaaataa tcagaatgat     8460

tcaagggtca aaccactttc atcccttaaa atatagggac taatatttct ttttcttttt     8520

tttaaaaaaa acatttcttc tgtggcttag aaatgtgcca gtgtgttcaa aacatttaca     8580

ccaatttcac cagatttagg acctattaaa aattcaaaca agtttctttt tttttttttt     8640

ttttctgtgt aacagggatt tttaaataac ggactatatg cattcttttg ttatttcaca     8700

cttcagttaa agtgataaca atggtaaact gtgatcatta tcagactgac tgaatgcttt     8760

ctgatttcca gtgagtgatc tagttctacg tattacacag gtgtaatatc tgtgagtgta     8820

aataactgga actgtacact gattaacatg acagtttctc ttttgttgtt cttatctgta     8880

ctgtattata gtatgtgggt ataaatatct acaagtatac acacatatgt acttgtattc     8940

cactattgta acctgaaaga aagactatgt attccctttt ttaattccgt actggtattt     9000

gtgttattta aaaagcaaaa ttctgctcta tttagttgta taatattaga ggatactttg     9060

ctgtgcacaa ttccaagtgc cttagaacat tgtttagctt tcctaagtat atataaatgc     9120

atatatgtat aaaattggga aaagttacct caataaaatc attgggaaat ccccagtttt     9180

agtttgttcc agtttctctt atatttggat agtgctcagc ctttttaaat gaaaaaagaa     9240

aaaagagtaa gacaacttcc ctaattgcct gttatttcag cttcacctaa gtttttaaca     9300

cctctttgta tgtaaggtct tgagacatgt aaggcctggt actttttatt taaaatgtct     9360

gtctaaagaa ttactgctct taaaagaaac ttccagtatt ttttttaact tgctatcttt     9420

ttatgtctga ggtatttgat attgatgttt ttattgccat tattatatgt aaacataaaa     9480

gatagtccat ttagagttta taatatagaa aataaacaga cttcctcatt aaaaaaaaaa     9540


<210>  625
<211>  9540
<212>  DNA
<213>  homo sapiens

<400>  625
agtgcatgaa gtatgctcag tgtgccagca agggctgata atcagcagaa ggacagggtg       60

cttcgttagt cagaagagcc agggcttccc ggctgccagg ctacagaact cgcctcgcca      120

ctcctgagac atggacaacg ccgttgacgg actggacaaa gcttctatag caaactcaga      180

tggccccaca gcaggttccc aaacacctcc cttcaaaaga aaggggaaac tatccaccat      240

tggtaaaatc tttaagcctt ggaaatggag gaaaaagaag accagcgaca aatttagaga      300

aacctcggca gtattagaaa ggaagatatc cacacgacaa agtagagagg agctgataag      360

aaggggagtg cttaaggaat tgcctgatca agatggagat gtaacagtta actttgaaaa      420

ttcaaacggg cacatgatac ccatcggaga ggaatctacc cgagaggaaa atgtagtaaa      480

gtctgaagaa ggtaatggct ctgtatctga aaaaacacca cctctggagg aacaggcaga      540

agataagaaa gagaacactg aaaaccactc tgaaacaccg gcagctcctg ctctacctcc      600

ttctgctcct cctaagccta gacccaaacc taaacccaaa aaatcacctg tgcctccgaa      660

aggggccact gctggggcca gccacaaagg tgatgaagtg cctcccatta aaaaaaatac      720

caaggctcct ggtaagcagg cccccgtccc tccacccaag ccagcaagcc gaaacacgac      780

ccgagaggct gctggctcct ctcattcaaa aaaaacaact ggctctaaag catcagcttc      840

gccatccact tcatccacct catctcgtcc caaagcttca aaggagacag tttctagcaa      900

agcagggaca gtggggacca ccaagggcaa gagaaaaact gacaagcagc caataacttc      960

tcacctgtcc tcagacacaa caacttctgg cacatccgac ctgaaaggag agcctgcaga     1020

gaccagagtg gagagtttca aactcgaaca gactgtccct ggagctgagg agcagaacac     1080

aggcaaattc aagtccatgg tccctccacc ccctgtggct ccagcacctt ctcctctggc     1140

cccccctctc cctcttgagg atcagtgcat tactgcctca gacactccag ttgtcctcgt     1200

cagcgttgga gctgacctgc ccgtctctgc cttagaccca agtcagcttc tttgggctga     1260

agagccgacg aacagaacca ctctctactc aggcactggc ttaagtgtta acagagaaaa     1320

tgcaaaatgt ttcacaacca aagaggagct ggggaagaca gtgcctcagc tactgactcc     1380

tgggctgatg ggcgaatctt cagaatcctt tagtgcctca gaagatgaag gccacaggga     1440

ataccaagcc aatgactctg actcggacgg gcctatcttg tacaccgatg atgaggacga     1500

agacgaagat gaggatggca gtggagaaag tgctttggca agtaaaatac gccggaggga     1560

tactcttgct atcaaacttg gcaacagacc atctaagaaa gaactagagg acaaaaacat     1620

cttgcagcgt acatctgaag aagagaggca ggaaatccga caacaaattg gaaccaagtt     1680

agtcaggagg ctgagccaga ggcccacaac tgaagaatta gagcaaagaa acatcctaaa     1740

acaaaagaat gaagaagagg aacaagaagc aaaaatggaa cttaaacgca gactcagcag     1800

aaagctcagc ctgagaccca cagtggcaga gctacaagct cgaaggatcc tgcgatttaa     1860

cgagtatgta gaagtcacgg attctcctga ctatgaccgc cgagcagaca agccctgggc     1920

caggttaaca cctgcagaca aggcagcaat aaggaaagaa ctaaatgaat ttaaaagcac     1980

agaaatggaa gttcatgaag agagtcgaca gtttacaagg tttcatcgtc cataacgaag     2040

agtgagacta tttggaaaca gagactgatc atctttgggg gaagccctgc ttcctgaaaa     2100

cctgatattg cactgggatt tgaatgtgtg tgtttccgtt taacttgtgg tgaaggaagt     2160

gtgtgactca gcttggctgg gaagtgctcc tcacctgtgt ggcccagatg gctccaacaa     2220

gcaaaaggaa ggatgcagtg actcttgctg cccagaatgc acagcgatgg taagagacac     2280

cgtggatatt cttcatcaga agctttaatc aaagaagatg agcagaagac aatcactggc     2340

tccctgttac cagaaagcca aattttataa tgcgggtgaa agaaaaatat agattaaaat     2400

tgctgggcac tgaaaagggg tgggagttgg aaatcagaaa gaaagagaaa tatttcatta     2460

tgttaatgaa gaaaagagaa aattgaagca taaatgtatt tttgaagtag ttattcggta     2520

gctgagaact tattaaggga tttaggaatt taacctcctg atgtggattc ctcaaagact     2580

tgatcggaga atactcttgt ttcaccatta tgttggtaca gtatagtacc attattttat     2640

gttgtgccag tgaatccagt tgccagaaat aagtctgaat gttttcatgc atctttttct     2700

taaatgcaag agcttctact gactcttaac aagcatgctt acccaaattt tgttgcatgc     2760

ttttaagtag cattagctat gcacacttga catttttaaa tatccctttc ctagtgtacc     2820

agccttcaca ggataagagg actgggaata aagtcagatg taatgtgacc ctagaaaact     2880

gtagcaagct tcagaaataa atcttttgat ctttccctat cttgattaga tccaaagtca     2940

aagcaaccat acttcaccta gagaagacag tattggcaat catgacacct gtaataaaaa     3000

cttgaatcca aagtcaaaac ttaagcaaga tacaaatgtg ctgcctgcag ttagtcctgc     3060

atgggaataa ggactagtta tttttttagt gctgcatttt tttaaagttg gattgctgct     3120

atttaaaaaa aaaaaaagga cacagatcaa aaaaacaccc aaaggcttaa cagaacatgg     3180

aaagttccca ctaagttgtg tgtgaggaaa tcctcatctt gtattttaag aatctgcaga     3240

tggcatccat agatacagta cagtatttac tgtcaatgca aaagaatcag tgaggttaaa     3300

gtagtggaag ttttccctat gagcctacag tctgtattgt ttacattaag aaactctcta     3360

ttattgtgtt gctattttcc atggagtcac aggcacacta tgacttctgc tcccaaatac     3420

atatgaccat atgtaaatac caccttgcat ttcattgttc ttcacaagtg ctttgtgccc     3480

ctttaattaa aaacacatga aatgaataac aaaacaagac ccaaatagag tttattttat     3540

tctcagagtt tggactacaa ttttctaaga tgtttctggt tcaagactgt cattttctat     3600

ttcaaccgaa aagtaagcat ttaacccggt gaataaatgt agatcctgcc attcattggt     3660

attttaaaga accacttgaa atcggatcat tttatttaaa aataaaaaat gttaatgcca     3720

gttggcctac tataaaaagc caggaccatg ttagaattag gaaaagtaac cagcattact     3780

gcacctcttg ttagactctg tgcattaata aaacacacct agagtctgtt gtcatttcac     3840

taataggata agacaaattt tttgctttga aaaaattttt ctgcatgccc aggtgtctgt     3900

ctctggctga ggttttgtct attttacagt gtttcaatcc agccataaaa attaacttgt     3960

gatttttttt ttcccaaagt catgcttttc cttaattata tttttatttt attattttag     4020

tgtcttgaga aaaataccaa gagatataat gtttctttta attgtctatg cttaatcatc     4080

tttaaacact ttttaaattt ctaaccacaa gacctctcta taatggtaaa tgtaagacat     4140

caccatttta tcactcaaag tatgttattg aaagtttcta tttggttgat aaaaggaaca     4200

attttttccc acttttgatg cctgtgatgc aattttttat tgcctacaat gagatacact     4260

tagtacaaaa aatgaaaatc tggtatttca aaattgcatt tcttgtataa taggtcagat     4320

ttattaacta ctcatacttt ttctttacac taatcgatac atttagaaaa aattttctaa     4380

gttagagaca agtttaaaag taaaaaaaaa aaaaaattag ccactgctag tctactgttt     4440

aggtaatcgg aatcaccaat tattttatta gaatgatggc ttgagtaaaa agctgtggaa     4500

agaattaaag gattatgagc taagctgtat tttgcagaat atggttctat tttagtagag     4560

cagagatgag acatatcccc accggccacc cagccagagg tctcctacct gggggcccta     4620

aagggatgca gaggtctggc ccaccctccg tgcataggca cctctgtcca ccaccagcgt     4680

ttcagcaatc caaccagtaa gcatatgctg tataggaaaa ataaaagtgt gtgggaattg     4740

gatttctttt gttgtaacac aattccaggt ttttggctat ttaaagtttg acattaggct     4800

gacatcgagg aagtaagtgg gttttcctga gttcccaaga tatgattaag gaagaaaaca     4860

aacccatctc caggaagatc ccaggcagga aagaactaga cagatgtaga aaccaaagtg     4920

accattttag tttttttatt ggagaataaa acattaatat tagggtatta agaagatgct     4980

cagcaagctt gatcagaatc ttcatggtca ttaccaatca gtctgacaaa atagttctct     5040

ggtagtcagc attcatttaa ggcagcttgc ctgataattt cctgtgttat gtgaagtgtc     5100

ttgcactttc acatgttagc tataattcct taaattactt aactgaaatc tgtaatagag     5160

aaccattttg gcatttgaac agctatttta catggagaaa aagcaaacac atctgtttgc     5220

tttacccaga aaaactgact ttctggtttc atcttcatat tgtttagtag cataatgaga     5280

gtagtccttt atctttctct aatgttagta aatatattct gttagtagga agttctgaaa     5340

ttgaagggaa aatatattta aggaaataaa ggaattcaat acacccttca aaagtcacca     5400

aatactgaaa ataagagatg agtccttaaa acctgagtca aaaaaggtcc agttttacag     5460

cctgcaatta attcagggct gcgttggcat taaaaaagaa aatatatata tatatatata     5520

tatatatata tatatatata tatatgtata ttatatatac agtagcttac acttaaaaga     5580

ggaaaaattt gcattaacat tgcatattct gatatgtacc atattaacac ataacaggca     5640

ttttatttat gcttcataga atcagacaga cacaactttc aaaaatctta ctgtattcac     5700

aatagaaaag ggtagtcttg tctaccacag aggagtatgt ccacacttaa taatgaaaac     5760

tttcttcctt tcctgcccaa aaatttcttc agtctgttat tatttttaag tgccccttgc     5820

tgcaaatttc aaacagagca agaaatcttc ctcagagtag gtggtatgaa attaaactag     5880

tacaatatat atgaattcat gtcatttacc cctgagtatg gtagaattgt taaagcattc     5940

ttaaattcca attatatgaa gcctatcatt actaggaaaa gtatattctt tgggataaga     6000

attaatttct tcacactatt agagcatgtt gtgagtagta aggaactact tagatgcaat     6060

ttatttacag aattgtccct tgacctcttg aaatggctag atctttcact actgtgtagg     6120

tagtctctac ttactggtag gatagattac attgctttac tggacaaagc agaatgaact     6180

tatataacta aaatatgtcc tatattggct gggtgcggtg gcttacacct gtaataccag     6240

cactttggga ggccaaggtg ggtggatcag ttgaggtcag gagttcgaga ccagcctggc     6300

caacatggtg aaaccctgtc tctactgaaa atacaaaaaa aaaaaagtat ctgggcatgg     6360

tggcttgtgc ctgtaatccc agctacttgg gaggctgagg cagggaaatc gcttaaaccc     6420

gggaggtgga ggttgcagtg ggcccagatc gtgccactcc actccagcct gggagacaga     6480

gcaagactcc atctcaaaat aataataata gtaataatga ataaaataaa ataaaatatg     6540

tcctccaggg aaaagcaatg acagagtaat caccaaatta ataggaacat ctttctagag     6600

aaagtacatg cccagttagt tcaaacccag gtttcaaaga agtagcactg ggctctactg     6660

taaaggcagg cagtgaccaa gaggtggtgg ggagagaggt agagtaccct caaatcattc     6720

ccattttcac ttccaatttc ccttttgtaa tcattaagct taagctatgt atggaaatgc     6780

aaagcaccat tagcatttct agaaagcagc tggaacctta cccaccaatg cttttttgaa     6840

gacagtatca tcccaaattt aaaaatccta ttgtatatgt tgtaaaattt ctggcaaaga     6900

aatggaggat cctgtggcag ctattcccac ctaaagccaa ccctataagg atgggtcatt     6960

ttttagccat gctaggattt actgcacaca caaaaaatgt catttagctt gtcacattgc     7020

tagcacagct gcacatatga gcaaagcact gttggtctgt gtttctcagt gggggtactc     7080

ttggcatttg gagctggata ggtctttgct gtacagaatc atcccatgca ttgccagatg     7140

tttaatatcc caggcccctg ctgactaaat gtcagtagca ttctcagtca ttgtaaacac     7200

caagaataaa aagcattccc ccaggttcaa atgccctccc tgggaggttg gtatcacctc     7260

ccctgaatgc cactgtctac tgcattttga ggacacaggg agaaaaagtg cctatcctca     7320

aacattgtct ctgctgcctt gcatttcttt gggccctgaa tggtttttct cccttcattt     7380

ttcgagcctt tctctcagtg cagctgttct tcagggagga ggttactggg cagccttggc     7440

cattcagtgg gcatggggac ttggcctagt ccctatatat atatacttaa agtccctata     7500

tatacttaaa ggagagatca tacatgaaga aagctttttt tttttttttt ttttttgcct     7560

tacaactttt ctttagaacc acattattgg tcataatcct tgttactgtc atgaggattg     7620

ttgcatgggt taaacacaaa cacagactag caatgcactt gaacaaacct ggtggtcttt     7680

ggaaataaat caccattaga tttcacctgg ttatgctgca tcccataagt tccaaatgaa     7740

tcacctgctt atcctattaa cgaagcattt aattcacaca caaatgcttg aatttcccct     7800

gtataaatgt agtcatgcga ttcaactttt ctaataagat ttgtgaatgc tgcatcatga     7860

tgaaaatgtg gattaactgt gggttgcatg cctgttgttc atacttcagt gatggtcaca     7920

cacaaaacaa gatgagtttt acttaggtga aacattatta aactgtacta acaatacaga     7980

aacatattct ctttgtcgct ttttatcacc aaaactgaat ggcaaatatg tcttgacatt     8040

acttggatga actgtggcta gcaaaatgga attaacttag ccactataat tttttaaaac     8100

attaaagttt ctaaattgtt tttggggccg agtaacgcag agtcaataaa ggtggttata     8160

ttgtaagctt ttagatggtg cttaagaatt cttatctttt taaatagcag tatttttttt     8220

ttaagaataa attgtaagga gcaaataagg cagaatgcca ctctaccctc aggtcaattt     8280

tatggtatat gaaaatgcca gtaatatttg tgccacttgc caactcgggg gaggaggggc     8340

ttttccctta ctggatactt ttgttatagt ttgactatgt cattatgttg tttagagagc     8400

ctccacaatg agaagttgcc actgcagggc taactcgcct tcagaaataa tcagaatgat     8460

tcaagggtca aaccactttc atcccttaaa atatagggac taatatttct ttttcttttt     8520

tttaaaaaaa acatttcttc tgtggcttag aaatgtgcca gtgtgttcaa aacatttaca     8580

ccaatttcac cagatttagg acctattaaa aattcaaaca agtttctttt tttttttttt     8640

ttttctgtgt aacagggatt tttaaataac ggactatatg cattcttttg ttatttcaca     8700

cttcagttaa agtgataaca atggtaaact gtgatcatta tcagactgac tgaatgcttt     8760

ctgatttcca gtgagtgatc tagttctacg tattacacag gtgtaatatc tgtgagtgta     8820

aataactgga actgtacact gattaacatg acagtttctc ttttgttgtt cttatctgta     8880

ctgtattata gtatgtgggt ataaatatct acaagtatac acacatatgt acttgtattc     8940

cactattgta acctgaaaga aagactatgt attccctttt ttaattccgt actggtattt     9000

gtgttattta aaaagcaaaa ttctgctcta tttagttgta taatattaga ggatactttg     9060

ctgtgcacaa ttccaagtgc cttagaacat tgtttagctt tcctaagtat atataaatgc     9120

atatatgtat aaaattggga aaagttacct caataaaatc attgggaaat ccccagtttt     9180

agtttgttcc agtttctctt atatttggat agtgctcagc ctttttaaat gaaaaaagaa     9240

aaaagagtaa gacaacttcc ctaattgcct gttatttcag cttcacctaa gtttttaaca     9300

cctctttgta tgtaaggtct tgagacatgt aaggcctggt actttttatt taaaatgtct     9360

gtctaaagaa ttactgctct taaaagaaac ttccagtatt ttttttaact tgctatcttt     9420

ttatgtctga ggtatttgat attgatgttt ttattgccat tattatatgt aaacataaaa     9480

gatagtccat ttagagttta taatatagaa aataaacaga cttcctcatt aaaaaaaaaa     9540


<210>  626
<211>  4596
<212>  DNA
<213>  homo sapiens

<400>  626
gaaaacttcc tggagaagga tggattttac cctgtaaaag aagaaagaca tggatgcata       60

agaagagggt tgaagagggg gaggcctcag acttctcgct ggcctgggat tcctccgtga      120

cagcagcagg aggcctagaa ggagagccag agtgcgatca gaaaaccagc cgtgcgctgg      180

aagacaggaa cagcgtgaca agtcaagagg agagaaatga ggatgatgaa gacatggagg      240

atgaatcaat ttacacctgc gatcactgtc agcaggactt cgagtctctg gcagacctga      300

cggaccaccg ggcccaccgc tgtcctggag atggtgatga cgacccacaa ctctcctggg      360

tggcctcgtc tccctccagc aaggatgttg cgtcacccac gcagatgatc ggagatggtt      420

gtgacctcgg cctcggcgag gaggaagggg gcacgggcct gccataccct tgccagttct      480

gcgacaagtc cttcatccgc ttgagctact tgaagaggca cgagcagatc cacagcgaca      540

agctgccgtt caagtgcacc tactgcagcc gcctcttcaa gcacaagagg agccgtgacc      600

ggcacatcaa gctgcatacg ggcgacaaga agtatcactg ccacgagtgc gaggcagcct      660

tctcccgcag cgaccacctc aagatccacc tgaagaccca cagctccagc aagcccttca      720

agtgcactgt gtgcaagcgc ggcttctcct ccaccagctc gctgcagagc cacatgcagg      780

cccacaaaaa gaacaaggag catctggcca agtcggagaa ggaagccaag aaggacgact      840

tcatgtgcga ctactgcgag gacaccttca gccagacgga ggagctggag aagcacgtgc      900

tcacccgcca cccgcagctg tccgagaagg cggacctgca gtgcattcac tgccctgagg      960

tcttcgtcga cgagaacaca ctgctcgccc atatccacca agcccacgcc aaccagaaac     1020

acaagtgccc catgtgccct gagcagttct cctcagtgga aggtgtctac tgccacctgg     1080

acagccaccg gcagcccgac tccagcaacc acagtgtcag tcccgaccct gtactgggca     1140

gcgtggcctc catgagcagc gccacacccg actccagcgc ctctgtggag cgtggctcca     1200

ccccggactc caccttgaag ccgctgcggg ggcagaagaa gatgcgggat gacgggcagg     1260

gctggaccaa ggtggtctat agctgcccct attgttccaa gcgggacttt aacagcctgg     1320

ccgtgctgga gatccacctg aagaccatcc acgcggacaa gccccagcag agccacacat     1380

gtcagatctg cctggactcc atgcccaccc tctacaacct caacgagcac gttcgcaagc     1440

tgcacaagaa ccatgcctac cctgtgatgc agtttggcaa catctctgcc ttccactgca     1500

actactgccc cgagatgttc gccgacatca atagcctgca ggagcacatc cgcgtctccc     1560

actgcggccc caacgccaac ccctctgacg gtaataatgc tttcttctgc aaccagtgct     1620

ccatgggttt ccttactgag tcctccctca ccgagcacat ccagcaggcc cactgcagtg     1680

tgggcagtgc caaactagag tctccggtgg tgcagcccac gcagtccttc atggaggtct     1740

attcctgccc ctactgcacc aactccccca tctttggctc catcctgaaa ctcaccaagc     1800

acatcaagga gaaccacaag aacattccac tggcccacag caagaagtcc aaggccgagc     1860

agagcccagt ctcgtccgat gtggaggtgt cttccccgaa gcggcagcgg ctctcagcaa     1920

gcgccaactc catctccaat ggggagtatc cttgcaatca atgcgacctc aagttctcca     1980

actttgagag cttccagacc cacctgaagc tgcacctgga gctgctgctg cggaagcaag     2040

cgtgccccca gtgcaaagag gactttgact cccaggagtc cctcctgcag cacctgacag     2100

tgcattacat gaccacgtcg acccactatg tgtgcgagag ctgcgacaag caattttcct     2160

cggtggatga cctgcagaag cacctgctgg acatgcacac ctttgtgttg taccactgca     2220

ccctgtgtca ggaggtcttc gactccaagg tgtccatcca ggtgcacctg gcggtgaagc     2280

acagcaatga gaagaagatg taccgctgca cggcctgcaa ctgggacttc cgcaaggagg     2340

ctgacctgca ggtgcacgtc aaacacagcc acctgggcaa cccggccaag gctcacaagt     2400

gcatcttctg tggggagacc ttcagcaccg aggtggagct gcagtgccac atcaccacac     2460

acagcaagaa gtataactgt aagttctgca gcaaggcctt ccacgccatc atcctgctgg     2520

agaagcacct gcgggagaag cactgtgtgt ttgatgctgc gaccgagaac ggcacggcca     2580

atggggtacc cccaatggcc accaagaaag ctgagcctgc tgacctgcag ggcatgctgc     2640

ttaagaaccc tgaggcacct aacagccatg aggccagcga ggatgacgtg gacgcgtcgg     2700

agcccatgta cggctgtgac atctgtgggg cggcctacac catggaggtg ctgctgcaga     2760

atcaccggct gcgggaccac aatatccggc cgggcgagga tgatggctca cgcaagaagg     2820

ctgagtttat caagggcagt cacaagtgca acgtttgttc acggactttc ttctcggaga     2880

acgggctacg ggagcacctg cagacgcacc ggggccctgc caagcactac atgtgtccca     2940

tctgtggtga gcgcttccct tcgctgctga cgctcaccga acacaaggtg acccacagca     3000

agagcctgga cacgggcacc tgtcgcatct gcaagatgcc cctgcagagc gaggaggagt     3060

ttattgagca ctgccagatg caccctgacc tgcgcaactc actcacgggc ttccgctgtg     3120

tggtctgcat gcagacagtc acttccacgc ttgagctcaa gatccatggc accttccaca     3180

tgcagaagct ggcgggcagc tcagcggcgt cctcccccaa tggccagggg ctgcagaagc     3240

tctacaagtg cgccctgtgc ctcaaggagt tccgcagcaa gcaggacctg gtgaagcttg     3300

acgtcaatgg gctgccctac ggcctctgcg ccggctgcat ggcccgcagc gccaacggac     3360

aggtgggtgg cctggccccg cccgagcccg ccgaccggcc ctgtgccggc ctccgttgcc     3420

ccgagtgcag tgtcaagttt gagagtgccg aagacctgga gagccacatg caggtggacc     3480

accgtgacct cacgccggag accagtgggc cccggaaagg cacccagaca tcgccagtgc     3540

cccggaaaaa gacataccag tgcatcaagt gccagatgac cttcgagaac gagagagaga     3600

tccaaatcca cgttgccaac cacatgattg aggaaggcat caaccacgag tgtaagctgt     3660

gcaaccagat gttcgactcc ccggccaagc tcctctgtca cctcattgag cacagcttcg     3720

agggcatggg cggcaccttc aaatgccccg tgtgtttcac agtcttcgtc caggccaaca     3780

agttgcagca gcacatcttt gccgtgcacg ggcaggagga caagatctac gactgctcac     3840

agtgccctca gaagttcttc ttccagaccg agctgcagaa ccacacgatg agccagcacg     3900

cacagtgagg gatcgctcaa caggacacct ctccgcagaa ggcttgccgg agacgccgtg     3960

gggagggcca tttgaacatt acatccaatc aaagtgtcat ttgcaaccca gatgtaaaac     4020

tctaatgatt tggccatgag gcgctgctat tataagcagc tggaaatgaa tattaatggc     4080

agagattaaa agtattccat gctcagtatt ttttattgtc ctgctacagc tagtgtgctt     4140

ttagactttc cgccgcagac tacatttcta gagttagaga aacctgcttt ttaaggctat     4200

tgtcctttgt tccttcatgt attatattga tagtttttaa aaaagaatta gtgtgatttt     4260

ttttctttgc ttcttttttt tctttcttgt ttttcttccc ccccaccccc cacccccttc     4320

ggttaactac tttttaattg caattctagg taattgtgca tcgtgatgtg attgcttggc     4380

tattgtctga atatttcctt ttaatttttt aattaaagac taatgctttg attggatttg     4440

ccagttcacc ggacagtgat taaaactatg taatgaatat aatcggtttc agtgcaactg     4500

gatggtctgc ttttaaatgt gacttaatct gactgcagta actagtacag ttcaataaag     4560

ggaatccatg cgattagcaa aaaaaaaaaa aaaaaa                               4596


<210>  627
<211>  4493
<212>  DNA
<213>  homo sapiens

<400>  627
aataagctgc tatattcttt ttccatcact tccctctcca aggctacagc gagctgggag       60

ctcttcccca cgcagaatgc ctgctttccc cagtgctcga cttccattgt ctaattccct      120

catcctggct ggggaaaggg agagctgcga gtcctcccgt tccgaggaac tccagctgaa      180

tgcagcttag ttgctggtgg tttctcggcc agcctctgtg gtctcaggga tctgcctatg      240

agcctgtggt ttctgagctg cctgcgagtc tgaggcctcg ggaatctgag tctttaggat      300

cagcctacga tatctgggct tcgcctgcaa gtctacgaat tcgagatcta cctgcgggtc      360

tgagacctcc gggacctgcc cgtgctctct agaatcttcc tgaacgccag gtctgagaga      420

acgctgcggc tctggaaccc gttcgcggtc tctcaggttt tggagacgac gatctagtgg      480

atcttttgcg ggacaggagc gctgtctgct agctgctttt cctgctctct ctccctggag      540

gcgaaccctt gtgctcgaga tggcagccac cctgctcatg gctgggtccc aggcacctgt      600

gacgtttgaa gatatggcca tgtatctcac ccgggaagaa tggagacctc tggacgctgc      660

acagagggac ctttaccggg atgttatgca ggagaattat ggaaatgttg tctcactaga      720

ttttgagatc aggagtgaga acgaggtaaa tcccaagcaa gagattagtg aagatgtaca      780

atttgggact acatctgaaa gacctgctga gaatgctgag gaaaatcctg aaagtgaaga      840

gggctttgaa agcggagata ggtcagaaag acaatgggga gatttaacag cagaagagtg      900

ggtaagctat cctctccaac cagtcactga tctacttgtc cacaaagaag tccacacagg      960

catccgctat catatatgtt ctcattgtgg aaaggccttc agtcagatct cagaccttaa     1020

tcgacatcag aagacccaca ctggagacag accctataaa tgttatgaat gtggaaaagg     1080

cttcagtcgc agctcacacc ttattcagca tcaaagaaca catactgggg agaggcctta     1140

tgactgtaac gagtgtggga aaagttttgg aagaagttct cacctgattc agcatcagac     1200

aatccacact ggagagaagc ctcacaaatg taatgagtgt ggaaaaagtt tctgccgtct     1260

ctctcaccta atccaacacc aaaggaccca cagtggtgag aaaccctatg agtgtgagga     1320

gtgtgggaaa agcttcagcc ggagctctca cctagctcag caccagagga cccacacggg     1380

tgagaaacct tatgaatgta acgaatgtgg ccgaggcttc agtgagagat ctgatctcat     1440

caaacactat cgagtccaca caggggagag gccctacaag tgtgatgagt gtgggaagaa     1500

tttcagtcag aactccgacc ttgtgcgtca tcgcagagcc cacacgggag agaagccata     1560

ccactgtaac gaatgtgggg aaaatttcag ccgcatctca cacttggttc agcaccagag     1620

aactcacact ggagagaagc catatgaatg caatgcttgt gggaaaagct tcagccggag     1680

ctctcatctc atcacacacc agaaaattca cactggagag aagccttatg agtgtaatga     1740

gtgttggcga agctttggtg aaaggtcaga tctaattaaa catcagagaa cccacacagg     1800

ggagaagccc tacgagtgtg tgcagtgtgg gaaaggtttc acccagagct ccaacctcat     1860

cacacatcaa agagttcaca cgggagagaa accttatgaa tgtaccgaat gtgagaagag     1920

tttcagcagg agctcagctc ttattaaaca taagagagtt catacggact aagctgtaat     1980

tatgatggct gagaaatgat tcatttgaag atacaatttt atttgatatc aatgaacgcc     2040

ctcaagactg agctgctttt atcatactct cctagttgtg ggccacgatt taaaccatca     2100

gagatgacaa gccatttgaa attctgaccc tcagctttgg gaatgttatc tcctccaaaa     2160

tggtgatttt tattcactca atgggttact tcattaaaag cagccccaca agtaactgga     2220

aatctgaaga ccaggggaca aatgctggtg aatgcttagg cctggaaatg gagtaaatct     2280

ttcaatgtta ttttctccca tccttggccc aaggaactat gctaagtgaa acgtgggact     2340

gtaatagggt ggtaatggct gctttggaaa aaggcaacta gagactctgc ctaaattgcc     2400

acacctattc acacaccata gtagttgggc acacacatct tcccttccaa agggcttttt     2460

ccttgagttg ctcatgcatt tgtatctttt ccatcttcct gagggcaaga ttttgcacga     2520

tgaaggcaat gattgtaact tttctccttc tcattgtttc taattagctc ctttaaagct     2580

tgcatctttg tgaaggctaa ctgaagatac ggttggaaag gaaaaatgag acacaggttt     2640

ggggaccaag gacccatcaa tgatggtgac tttagcagaa gatgcccaca gttattactg     2700

ccattaatca gatttatgaa ttttctttgg ggatcactat agggaatatt gtatagaaaa     2760

tatcttcaag aaaagatagg accatcagtg acagttaagt gtaaggagca agtggaattg     2820

agtccttcag ggaaggaacc acagagtccc ttcccaagga atgtaggtcg tttctgtgtt     2880

ctttcccttc taatctttaa gatcaactct tcctatcctg ctaactctaa gatttgataa     2940

gggccacatc ccagtgttta tcttagcttg catcagggca tgtgtatgta cagtaatgtg     3000

tattcctgtg gtttttctaa tagaaactga atttacagag acttagcatg ttcttgggtg     3060

atgtgagtca tgtgacagaa gtacagacat aactccaatg tgagaaatgt ccttttttca     3120

ttatggaaaa taatttaaac actagtgctt tagtgtgcac tctcctgtaa ggtctgtctt     3180

tgtacagagc taagcacttg tttgtatgtg tttgtcaatt gtggaagata atgaccagac     3240

aaataggtcg attgtcctat tctcagaatg aattatcttc tatggtaatg aagaactctt     3300

tggcttagtc agaaggaatt aacgaacctc ggtaggaatg tatttccatc ctcccaccct     3360

acagatataa gaggttaaaa taacagttcg cccaatttaa gcccagtagt gtcagttttc     3420

ctaatctcag tccaggtagg aattaagaaa tatctcaagt gttgatgcta tccaagcatg     3480

ttggggtgga agggaattgg tgcccagaaa atgggactgg agtgaggaat atcttttctt     3540

ttgagagtac ccccagttta tttctactgt gctttattgc tactgttctt tattgtgaat     3600

gttgtaacat tttaaaaatg ttttgccata gctttttagg acttggtgtt aaaggagcca     3660

gtggtctctc tgggtgggta ctataatgag ttattgtgac ccacagctgt gtgggaccac     3720

atcacttgtt aataacacaa cctttaaagt aacccatctt ccaggggggt tccttcatgt     3780

tgccactcct ttttaaggac aaactcaggc aaggagcatg tttttttgtt atttacaaaa     3840

tctagcagac tgtgggtatc catattttaa ttgtcgggtg acacatgttc ttggtaacta     3900

aactcaaata tgtcttttct catatatgtt gctgatggtt ttaataaatg tcaaagttct     3960

cctgttgctt ctgtgagcca ctatgggtat cagcttggga gtggccatag atgaccgcat     4020

ttccatgacc taactgtatt tcaccccctt ttccttccct actgttcttg ccccacccca     4080

accagttcct gctgctgctt ttggcttctt ggaggtgaag ggcttaaaac aaggcttcta     4140

agcacccagc tatctccata catgaacaat ctagctggga aacttaaggg acaagggcca     4200

caccagctgt ctcctctttc tgccaattgt tgcccgtttg ctgtgttgaa ctttgtatag     4260

aactcatgca tcagactccc ttcactaatg ctttttgcat gccttctgct cccaagtccc     4320

tggctgcctc tgcacatccc gtgaacactt tgtgcctgtt ttctatggtt gtggagaatt     4380

aatgaacaaa tcaatatgta gaacagtttt ccttatggta ttggtcacag ttatcctagt     4440

gtttgtatta ttctaacaat attctataat taaaaatata atttttaaag tca            4493


<210>  628
<211>  3734
<212>  DNA
<213>  homo sapiens

<400>  628
cctctttctc ccccctctct ccctcctctc ctctctctct cctctcttct ctgaacctct       60

cttctctttc tcttttctta catattctac tagttgtttt ccccttcttc ttctcctttc      120

tctccttttt ctccctcctc cttgtctctt ttactccatt cctgcagaag agagagggct      180

aaacttaaag aaaaaaaaaa ggaggaggag gaggaggagg cacccccttc gtattcttct      240

tatcgttatt ttatacatat atgatttttt ttggagggag ggtgttggtt gccggctgaa      300

gagcacttat ttaaaatact aaaaaaagaa catttttggg cgatctccag ggttttttta      360

actagctctg tgtgttatag cagaagaagc agaagaagga gcaagaaaga ggaaaagaag      420

aggattattt attcgaccta ctttggatgt ctctctcgct tttccttttt cctttttttg      480

gcaattattt tcttctgatt tttatttttt ctatttcgct gtgatttcgt cgccggcgtg      540

aattatcccg tatttttctc ccccttccgt cacctcccga aagaagaagg cagcgagagc      600

ccggcgccac cggcacaaca aaaagagcaa agtgtgtgat cttcctcgcc ggctgcctcc      660

cgctctccag cgctgccttc ctgaatggct ggctgcgtcc ggccctggac ctggcccccc      720

gacacccgcg cgccctgatc gccggcggca gcctcgccca gcgccctgct cggctcaccg      780

cgctccccgc actcccgagc ccggcgaggg ctcccgccgg gacagcggcg gcgccgcggg      840

cggccccggc ctccgctcgc gctccggctg cggccccgac tcctgctcgg actccggccc      900

gggtcccggc tcctccagcg gcgctcgccg cagcagctcc ggcggcagct ccagcggcgc      960

ctgcagccgc gacctcctcc tcctccgccg ccgccgccgc ctccgccctc gccggcttcc     1020

tctatgtcgg ctcagcccgc gcgctgcgcg tagcccgagc ggccggcggg cgggcgcccg     1080

gcgcgggtga gcgactgtgt gtgcgagtgt gtgtgtgcgc gggggtgcgg gcgaggcgga     1140

gggcgagtgt gtgcgcgcgc cgtggcccat gcccgccgcc cccggcgctg cgccccgcgc     1200

cgctcccggc tgccgcctgt gccatttctg attttgcaac ttggggaaga agaaaaaagc     1260

gagagaaggg agcttgctcg ccggggggtg gggagggggg aaggagagcg cggccccccc     1320

aggaacggag cgcgggggga gcgggcgagg ggagcagggg tgttgggggg ggagcctgag     1380

agcctggggg ggctgcaaaa agagagaaag aaaacagcag gaaccacaac aaaacgccag     1440

cagggcgggc gggcgcgcag cagcagcggg gcggccgagg cagtagcggc ggcagcggcg     1500

gcggcggcgg aggcagcggc cggtgtccgg ctcgggctcg gctcctgcga ccccggggcg     1560

cccggcgggc cccccgcccc ctccccctcc ccccttcccc ttccccttcc cctcccagcg     1620

cgcccgcgcg ccccgcggcc ctcggcgagc agctcggctc cccccagcgc tccccgggcc     1680

caaagatatg gcaatggtag ttagcagctg gcgagatccg caggacgacg tggccggggg     1740

caaccccggc ggccccaacc ccgcagcgca ggcggcccgc ggcggcggcg gcggcgccgg     1800

cgagcagcag cagcaggcgg gctcgggcgc gccgcacacg ccgcagaccc cgggccagcc     1860

cggagcgccc gccacccccg gcacggcggg ggacaagggc cagggcccgc ccggttcggg     1920

ccagagccag cagcacatcg agtgcgtggt gtgcggggac aagtcgagcg gcaagcacta     1980

cggccaattc acctgcgagg gctgcaaaag tttcttcaag aggagcgtcc gcaggaactt     2040

aacttacaca tgccgtgcca acaggaactg tcccatcgac cagcaccacc gcaaccagtg     2100

ccaatactgc cgcctcaaga agtgcctcaa agtgggcatg aggcgggaag cggttcagcg     2160

aggaagaatg cctccaaccc agcccaatcc aggccagtac gcactcacca acggggaccc     2220

cctcaacggc cactgctacc tgtccggcta catctcgctg ctgctgcgcg ccgagcccta     2280

ccccacgtcg cgctacggca gccagtgcat gcagcccaac aacattatgg gcatcgagaa     2340

catctgcgag ctggccgcgc gcctgctctt cagcgccgtc gagtgggccc gcaacatccc     2400

cttcttcccg gatctgcaga tcaccgacca ggtgtccctg ctacgcctca cctggagcga     2460

gctgttcgtg ctcaacgcgg cccagtgctc tatgccgctg cacgtggcgc cgttgctggc     2520

cgccgccggc ctgcatgcct cgcccatgtc tgccgaccgc gtcgtggcct tcatggacca     2580

catccgcatc ttccaggagc aggtggagaa gctcaaggcg ctacacgtcg actcagccga     2640

gtacagctgc ctcaaagcca tcgtgctgtt cacgtcagac gcctgtggcc tgtcggatgc     2700

ggcccacatc gagagcctgc aggagaagtc gcagtgcgca ctggaggagt acgtgaggag     2760

ccagtacccc aaccagccca gccgttttgg caaactgctg ctgcgactgc cctcgctgcg     2820

caccgtgtcc tcctccgtca tcgagcagct cttcttcgtc cgtttggtag gtaaaacccc     2880

catcgaaact ctcatccgcg atatgttact gtctgggagc agcttcaact ggccttacat     2940

gtccatccag tgctcctaga ccttgggcgc ttcccacctg ccccgtcccc ctagagactc     3000

agaggaccca cctgggccaa ggactccaaa gccgcgggga caccgggaag tgcagcgggc     3060

caggcaggct gggtgggagg gaggagggcc gagacaggag cagcccaccc agcagaaata     3120

caatccgagc tacaaagcat gggaaaaaga gactctttta ggatcagatc tgtgagcacg     3180

ttggcgagga aaaacaaaac aaacaaaaaa aagaaccttg tgtctgtctg gtgaaaaaaa     3240

gaaaaacaaa ttggaagaga ggaccatgag aattttaata aaacagaagg aaactaatgg     3300

accttccagg atttattgtg gacggatgtg gatatattct gtacaggaac aacacatatg     3360

gaagtggact gaagcctatg tagaaacaca cacacactga acattgttat tcattttgta     3420

aaatactagt ctttattttc attttttgta aaatttaaac atcgtatgcg cataaagaaa     3480

aaggaaacaa gaattagggg aaaataacat tttccaaata attataaaaa attgtcctgt     3540

gtctatgtat ctatatctgt tttgtatttt tttctggttc caaaccagat ttcctgtgat     3600

tctatactaa taatttttga tataaccctt tgcttcttat aatgagtgcg atatatgttg     3660

tcgaggctgt tcttcaagaa ttaaaattga agtgaaaatt taaacaaaaa taaaagaatt     3720

tagcaaaaaa aaaa                                                       3734


<210>  629
<211>  1023
<212>  DNA
<213>  homo sapiens

<400>  629
actggtgacg tagatctcat gtgaccagga gtcgacgtgt gcagaagtcc tggtaatctg       60

gtccttgttc ccgtctggat accagcttcc ttcagcagcg caggcggtgg tccctgaggc      120

ccgtggaagg agtcaaactt gcgggaattt tgcagaagtc attgtattca aagaagaata      180

agcaagaaag aaaagaagga aggaagagag gtagacagat acaagatgaa atcctgtcaa      240

aaaatggaag gaaaaccaga aaatgagagt gaaccaaagc atgaggaaga gccaaagcct      300

gaggaaaagc cagaagagga ggagaagcta gaggaggagg ccaaagcaaa aggaactttt      360

agagaaaggc tgattcaatc tctccaggag tttaaagaag atatacacaa caggcattta      420

agcaatgaag atatgtttag agaagtggat gaaatagatg agataaggag agtcagaaac      480

aaacttatag tgatgcgttg gaaggttaat cgaaaccatc cttaccccta tttaatgtag      540

tttaccttga tttttatctg atattaacaa taccatatag cttgcttttt attagcattt      600

cctgatattc ctttgtccat atttctactt ataacctgtt gctattaatg gttttagatg      660

tatctcttgt tatctgcatc tcattgttta ttgtattttg aaccaatcta caagtctctg      720

tcttttaata aaagaacttt acacatttgt aaaaaagagg ttcttggtaa gatataaaat      780

ggaaaaaggc taagtaatat gtgaatatca tatttttgaa aggtaaaaag tacatttgta      840

tattacatat atggacataa cttgtgaagg atgaaagaaa gtacagcctc tcggtggtgg      900

gattatgaat gatttttctc cttttgcttg tttgtatttt ctatattcct aaaattaaca      960

cacattatta ttgctagaat aataaaagtt ttataaaaaa gaagcaacaa aaaaaaaaaa     1020

aaa                                                                   1023


<210>  630
<211>  2995
<212>  DNA
<213>  homo sapiens

<400>  630
ggtgactctc ggagcgggag gcggaggctg aggcggccgc tcctgctgct gctactgccg       60

ccgccgcagc ggctgctcgg gctgagcacg ccccggaaca ggccgccgcg cgctgcgcgc      120

cggacccgct gcccctgccg gcccggccgg gtcgggcggc ccagggaccg acagacttga      180

caacggtgac agcactgggg cggcaccttc ctacttctgc ccagccacag ccctcccctc      240

acagttgagc acctgtttgc ctgaagttaa tttccagaag caggagtccc cagagccagg      300

cagggggatg aaccgcgagg gagctcccgg gaagagtccg gaggagatgt acattcagca      360

gaaggtccga gtgctgctca tgctgcggaa gatgggatca aacctgacag ccagcgagga      420

ggagttcctg cgcacctatg caggggtggt caacagccag ctcagccagc tgcctccgca      480

ctccatcgac cagggtgcag aggacgtggt gatggcgttt tccaggtcgg agacggaaga      540

ccggaggcag tagctgcaaa gcccttggaa caccctggat gctgttgagg gccaagagat      600

ctgtgtggct cctgggccgg ctgagtggca gcagcccccc ttgccccacc tcccccttcc      660

cctacccaac cctgccctgc cccaccccac ctcacagcta ctcagtgggg ctggcatcaa      720

gggagacacc agtggtgcgt ttataattgg cttaaaggga tggacttgtg attggctgca      780

ggaagaaact tttttatttt ttaaatcttg accaacagaa accttttatt tttatttctg      840

actcttattt tttaaaaaat ttgcgcctcg gtatctggct tccctggaag ctctccgagc      900

tctggtgctt tagttaggtc atttttttag aaatgtgaag aggtctgatt ggctgcttaa      960

actggaaagg atctgtgatt ggctggttaa tgggaaacgg tttttttctt tggctgcagg     1020

tgttctgctg atatcaacag cttccctatt ttgaatgcag aaaacagggt ctgggacatt     1080

agtcgttata tttgacttga aaagaaagaa accaagtgcg ctttgcaata tttattacac     1140

aaagaacttg ctgctgcctt cacatttggg gtttgtgttt gattggcttt cgatgcgtgt     1200

gtttggtttc ccattggttc acctgtgact cctgttgcca tggattcacc cccctctgct     1260

gccggctctg ggcctgaggg tccacctgga gagtacattt gctttaatga gtgcacctgc     1320

ctccaccagc aaggggaccc cgagaaccct gagcagggtc cacagctgga aagttgggcc     1380

cctgaggagc tttgtgtcgt cttgaacgag cagcccaggg cctagaggta accgttaggc     1440

gggatttatg tgcactgcct gcatgagctg gcaaccagcc agcgtccctt ggtgagaaag     1500

ggattgctga ggcaccgtcc aggccccacc ggccaggccg cgcccagcag aggcgtacta     1560

cccagctctg tcctcttggc catccttctg tgtaccactt cctgaggcct cattttgggg     1620

gtcatcttgg aaaggggagg agcttctccc agtgtgagac cccaaagact ctggaggtca     1680

tctggcggag gtctctggga gcccagaacc cacataaaag ccccagcttg gctcacaagg     1740

cccaggagac ctccagctaa acaccaaccc ctgacctacc ccagccaggc tcctacctgt     1800

ctgctgccag cacagtaggt cccggccagc tctggagttc tctcatcgga ggcccatgcc     1860

ctccactcca ctgcctttgg aagggtctct ctccaggtca gcctggaagg gacagtatcg     1920

tttgtttatg aaatgccact gggacagctg gctgggcctt caccaagcaa gtcccttcag     1980

actggccctt aagccaaact caggcccaga attgcagttc agaatggcag tcctggaggc     2040

agggggtgag gggcaggtct agtgttcctg caccaaacct aagtccttcc acctgccacc     2100

cccttccctg ggagggaggt ggtcctccta tctccctggc tcactggcag gtgtgggatc     2160

tggggagagc ggctggagaa agatgcagtc ctcaggaagg gggccgccac cctcccctat     2220

gctggtagat gctgaggccc ctaggtgccc agggccagtg ggaccctctc agaaccaaat     2280

ctttcccctt tctcggggct tggggctcgg gccgtagggg ctcctgagtg tcatgaagtg     2340

cacaggagcc aaatgaccga gccctggaga gccccatggt gggtaggtgg ttcgtgctgt     2400

gctctggcac catcagcctg ttccagaagg aggattcgag catcaggcta agaccctgtg     2460

tcctccacca tgcactcacc cctagccctg gttagctgac agtcagctgt ggggaacaca     2520

gctacaaccc taccctggca gggacctgag agcatctcag gaggggcagc gcatgtgtgc     2580

atgtgctgtg tgagtgagca cacccgtgtg cacactcata cacatgtgca cacacacgca     2640

ctctccccgc tcaggggcct ggaggtctgg ctgagcccct ggggaaaggt gagttctttc     2700

atctccctcc tccaggtcgg agtgcctgga gtcaggtgtc gaggccacat tgctggctgc     2760

cccctctttg tagctcctat aaagggccca cacctggtgg atacctggtt gagtgtgtgg     2820

tctctgcccc agcctgtcct tgtcacgatc acaggccttg cttttgtaac aatgatgacc     2880

ccggcctgtc tcatcttctg aagaggaaaa gtcaaagtgt tgctgtggct ccatatttca     2940

actaaaaata tatctgttgg agaaagaaat taacaataaa gaattttcat aggtt          2995


<210>  631
<211>  4871
<212>  DNA
<213>  homo sapiens

<400>  631
agtccctgcc ctcccctggg gagggtgagt cacgccaaac tgggcggaga gtccgctggc       60

ctcactccta gctcatctgg gcggcggcgg caagtgggga cagggcgggt ggcgcatcac      120

cggcgcggag gcaggaggag cagtctcatt gttccgggag ccgtcaccac agtaggtccc      180

tcggctcagt cggcccagcc cctctcagtc ctccccaacc cccacaaccg cccgcggctc      240

tgagacgcgg ccccggcggc ggcggcagca gctgcagcat catctccacc ctccagccat      300

ggaagacctg gaccagtctc ctctggtctc gtcctcggac agcccacccc ggccgcagcc      360

cgcgttcaag taccagttcg tgagggagcc cgaggacgag gaggaagaag aggaggagga      420

agaggaggac gaggacgaag acctggagga gctggaggtg ctggagagga agcccgccgc      480

cgggctgtcc gcggccccag tgcccaccgc ccctgccgcc ggcgcgcccc tgatggactt      540

cggaaatgac ttcgtgccgc cggcgccccg gggacccctg ccggccgctc cccccgtcgc      600

cccggagcgg cagccgtctt gggacccgag cccggtgtcg tcgaccgtgc ccgcgccatc      660

cccgctgtct gctgccgcag tctcgccctc caagctccct gaggacgacg agcctccggc      720

ccggcctccc cctcctcccc cggccagcgt gagcccccag gcagagcccg tgtggacccc      780

gccagccccg gctcccgccg cgcccccctc caccccggcc gcgcccaagc gcaggggctc      840

ctcgggctca gtggatgaga ccctttttgc tcttcctgct gcatctgagc ctgtgatacg      900

ctcctctgca gaaaatatgg acttgaagga gcagccaggt aacactattt cggctggtca      960

agaggatttc ccatctgtcc tgcttgaaac tgctgcttct cttccttctc tgtctcctct     1020

ctcagccgct tctttcaaag aacatgaata ccttggtaat ttgtcaacag tattacccac     1080

tgaaggaaca cttcaagaaa atgtcagtga agcttctaaa gaggtctcag agaaggcaaa     1140

aactctactc atagatagag atttaacaga gttttcagaa ttagaatact cagaaatggg     1200

atcatcgttc agtgtctctc caaaagcaga atctgccgta atagtagcaa atcctaggga     1260

agaaataatc gtgaaaaata aagatgaaga agagaagtta gttagtaata acatccttca     1320

taatcaacaa gagttaccta cagctcttac taaattggtt aaagaggatg aagttgtgtc     1380

ttcagaaaaa gcaaaagaca gttttaatga aaagagagtt gcagtggaag ctcctatgag     1440

ggaggaatat gcagacttca aaccatttga gcgagtatgg gaagtgaaag atagtaagga     1500

agatagtgat atgttggctg ctggaggtaa aatcgagagc aacttggaaa gtaaagtgga     1560

taaaaaatgt tttgcagata gccttgagca aactaatcac gaaaaagata gtgagagtag     1620

taatgatgat acttctttcc ccagtacgcc agaaggtata aaggatcgtt caggagcata     1680

tatcacatgt gctcccttta acccagcagc aactgagagc attgcaacaa acatttttcc     1740

tttgttagga gatcctactt cagaaaataa gaccgatgaa aaaaaaatag aagaaaagaa     1800

ggcccaaata gtaacagaga agaatactag caccaaaaca tcaaaccctt ttcttgtagc     1860

agcacaggat tctgagacag attatgtcac aacagataat ttaacaaagg tgactgagga     1920

agtcgtggca aacatgcctg aaggcctgac tccagattta gtacaggaag catgtgaaag     1980

tgaattgaat gaagttactg gtacaaagat tgcttatgaa acaaaaatgg acttggttca     2040

aacatcagaa gttatgcaag agtcactcta tcctgcagca cagctttgcc catcatttga     2100

agagtcagaa gctactcctt caccagtttt gcctgacatt gttatggaag caccattgaa     2160

ttctgcagtt cctagtgctg gtgcttccgt gatacagccc agctcatcac cattagaagc     2220

ttcttcagtt aattatgaaa gcataaaaca tgagcctgaa aaccccccac catatgaaga     2280

ggccatgagt gtatcactaa aaaaagtatc aggaataaag gaagaaatta aagagcctga     2340

aaatattaat gcagctcttc aagaaacaga agctccttat atatctattg catgtgattt     2400

aattaaagaa acaaagcttt ctgctgaacc agctccggat ttctctgatt attcagaaat     2460

ggcaaaagtt gaacagccag tgcctgatca ttctgagcta gttgaagatt cctcacctga     2520

ttctgaacca gttgacttat ttagtgatga ttcaatacct gacgttccac aaaaacaaga     2580

tgaaactgtg atgcttgtga aagaaagtct cactgagact tcatttgagt caatgataga     2640

atatgaaaat aaggaaaaac tcagtgcttt gccacctgag ggaggaaagc catatttgga     2700

atcttttaag ctcagtttag ataacacaaa agataccctg ttacctgatg aagtttcaac     2760

attgagcaaa aaggagaaaa ttcctttgca gatggaggag ctcagtactg cagtttattc     2820

aaatgatgac ttatttattt ctaaggaagc acagataaga gaaactgaaa cgttttcaga     2880

ttcatctcca attgaaatta tagatgagtt ccctacattg atcagttcta aaactgattc     2940

attttctaaa ttagccaggg aatatactga cctagaagta tcccacaaaa gtgaaattgc     3000

taatgccccg gatggagctg ggtcattgcc ttgcacagaa ttgccccatg acctttcttt     3060

gaagaacata caacccaaag ttgaagagaa aatcagtttc tcagatgact tttctaaaaa     3120

tgggtctgct acatcaaagg tgctcttatt gcctccagat gtttctgctt tggccactca     3180

agcagagata gagagcatag ttaaacccaa agttcttgtg aaagaagctg agaaaaaact     3240

tccttccgat acagaaaaag aggacagatc accatctgct atattttcag cagagctgag     3300

taaaacttca gttgttgacc tcctgtactg gagagacatt aagaagactg gagtggtgtt     3360

tggtgccagc ctattcctgc tgctttcatt gacagtattc agcattgtga gcgtaacagc     3420

ctacattgcc ttggccctgc tctctgtgac catcagcttt aggatataca agggtgtgat     3480

ccaagctatc cagaaatcag atgaaggcca cccattcagg gcatatctgg aatctgaagt     3540

tgctatatct gaggagttgg ttcagaagta cagtaattct gctcttggtc atgtgaactg     3600

cacgataaag gaactcaggc gcctcttctt agttgatgat ttagttgatt ctctgaagtt     3660

tgcagtgttg atgtgggtat ttacctatgt tggtgccttg tttaatggtc tgacactact     3720

gattttggct ctcatttcac tcttcagtgt tcctgttatt tatgaacggc atcaggcaca     3780

gatagatcat tatctaggac ttgcaaataa gaatgttaaa gatgctatgg ctaaaatcca     3840

agcaaaaatc cctggattga agcgcaaagc tgaatgaaaa cgcccaaaat aattagtagg     3900

agttcatctt taaaggggat attcatttga ttatacgggg gagggtcagg gaagaacgaa     3960

ccttgacgtt gcagtgcagt ttcacagatc gttgttagat ctttattttt agccatgcac     4020

tgttgtgagg aaaaattacc tgtcttgact gccatgtgtt catcatctta agtattgtaa     4080

gctgctatgt atggatttaa accgtaatca tatctttttc ctatctatct gaggcactgg     4140

tggaataaaa aacctgtata ttttactttg ttgcagatag tcttgccgca tcttggcaag     4200

ttgcagagat ggtggagcta gaaaaaaaaa aaaaaaagcc cttttcagtt tgtgcactgt     4260

gtatggtccg tgtagattga tgcagatttt ctgaaatgaa atgtttgttt agacgagatc     4320

ataccggtaa agcaggaatg acaaagcttg cttttctggt atgttctagg tgtattgtga     4380

cttttactgt tatattaatt gccaatataa gtaaatatag attatatatg tatagtgttt     4440

cacaaagctt agacctttac cttccagcca ccccacagtg cttgatattt cagagtcagt     4500

cattggttat acatgtgtag ttccaaagca cataagctag aagaagaaat atttctagga     4560

gcactaccat ctgttttcaa catgaaatgc cacacacata gaactccaac atcaatttca     4620

ttgcacagac tgactgtagt taattttgtc acagaatcta tggactgaat ctaatgcttc     4680

caaaaatgtt gtttgtttgc aaatatcaaa cattgttatg caagaaatta ttaattacaa     4740

aatgaagatt tataccattg tggtttaagc tgtactgaac taaatctgtg gaatgcattg     4800

tgaactgtaa aagcaaagta tcaataaagc ttatagactt aaaaaaaaaa aaaaaaaaaa     4860

aaaaaaaaaa a                                                          4871


<210>  632
<211>  8436
<212>  DNA
<213>  homo sapiens

<400>  632
attttgaccg ctatttagaa gagtgacctc ataaatcttt tagcaaagta gacacacata       60

cctaccacat ttcttaaaag tagattcgta ttttgatttg agattgttga aaagcatggt      120

atgtttggag tgcacttagt tatgtcccat ctcataaaga ctgttgagct ctctgcactg      180

ctgatgatga agcattgcat gaacccagaa aacggggatg ccaaagcaca gggcttaggt      240

gctgttcctt gcgtcatcag cagaggtctg tccactttgt agaagggaga gtcccgtatt      300

ctcagagtaa aagttgtttc tggaattgat ctcgccaaaa aggacatctt tggagccagt      360

gatccgtatg tgaaactttc attgtacgta gcggatgaga atagagaact tgctttggtc      420

cagacaaaaa caattaaaaa gacactgaac ccaaaatgga atgaagaatt ttatttcagg      480

gtaaacccat ctaatcacag actcctattt gaagtatttg acgaaaatag actgacacga      540

gacgacttcc tgggccaggt ggacgtgccc cttagtcacc ttccgacaga agatccaacc      600

atggagcgac cctatacatt taaggacttt ctcctcagac caagaagtca taagtctcga      660

gttaagggat ttttgcgatt gaaaatggcc tatatgccaa aaaatggagg tcaagatgaa      720

gaaaacagtg accagaggga tgacatggag catggatggg aagttgttga ctcaaatgac      780

tcggcttctc agcaccaaga ggaacttcct cctcctcctc tgcctcccgg gtgggaagaa      840

aaagtggaca atttaggccg aacttactat gtcaaccaca acaaccggac cactcagtgg      900

cacagaccaa gcctgatgga cgtgtcctcg gagtcggaca ataacatcag acagatcaac      960

caggaggcag cacaccggcg cttccgctcc cgcaggcaca tcagcgaaga cttggagccc     1020

gagccctcgg agggcgggga tgtccccgag ccttgggaga ccatttcaga ggaagtgaat     1080

atcgctggag actctctcgg tctggctctg cccccaccac cggcctcccc aggatctcgg     1140

accagccctc aggagctgtc agaggaacta agcagaaggc ttcagatcac tccagactcc     1200

aatggggaac agttcagctc tttgattcaa agagaaccct cctcaaggtt gaggtcatgc     1260

agtgtcaccg acgcagttgc agaacagggc catctaccac cgcccagtgc cccagctggg     1320

agagcgcgtt catcaactgt cacgggtggt gaggaaccaa cgccatcagt ggcctatgta     1380

cataccacgc cgggtctgcc ttcaggctgg gaagaaagaa aagatgctaa ggggcgcaca     1440

tactatgtca atcataacaa tcgaaccaca acttggactc gacctatcat gcagcttgca     1500

gaagatggtg cgtccggatc agccacaaac agtaacaacc atctaatcga gcctcagatc     1560

cgccggcctc gtagcctcag ctcgccaaca gtaactttat ctgccccgct ggagggtgcc     1620

aaggactcac ccgtacgtcg ggctgtgaaa gacacccttt ccaacccaca gtccccacag     1680

ccatcacctt acaactcccc caaaccacaa cacaaagtca cacagagctt cttgccaccc     1740

ggctgggaaa tgaggatagc gccaaacggc cggcccttct tcattgatca taacacaaag     1800

actacaacct gggaagatcc acgtttgaaa tttccagtac atatgcggtc aaagacatct     1860

ttaaacccca atgaccttgg cccccttcct cctggctggg aagaaagaat tcacttggat     1920

ggccgaacgt tttatattga tcataatagc aaaattactc agtgggaaga cccaagactg     1980

cagaacccag ctattactgg tccggctgtc ccttactcca gagaatttaa gcagaaatat     2040

gactacttca ggaagaaatt aaagaaacct gctgatatcc ccaataggtt tgaaatgaaa     2100

cttcacagaa ataacatatt tgaagagtcc tatcggagaa ttatgtccgt gaaaagacca     2160

gatgtcctaa aagctagact gtggattgag tttgaatcag agaaaggtct tgactatggg     2220

ggtgtggcca gagaatggtt cttcttactg tccaaagaga tgttcaaccc ctactacggc     2280

ctctttgagt actctgccac ggacaactac acccttcaga tcaaccctaa ttcaggcctc     2340

tgtaatgagg atcatttgtc ctacttcact tttattggaa gagttgctgg tctggccgta     2400

tttcatggga agctcttaga tggtttcttc attagaccat tttacaagat gatgttggga     2460

aagcagataa ccctgaatga catggaatct gtggatagtg aatattacaa ctctttgaaa     2520

tggatcctgg agaatgaccc tactgagctg gacctcatgt tctgcataga cgaagaaaac     2580

tttggacaga catatcaagt ggatttgaag cccaatgggt cagaaataat ggtcacaaat     2640

gaaaacaaaa gggaatatat cgacttagtc atccagtgga gatttgtgaa cagggtccag     2700

aagcagatga acgccttctt ggagggattc acagaactac ttcctattga tttgattaaa     2760

atttttgatg aaaatgagct ggagttgctc atgtgcggcc tcggtgatgt ggatgtgaat     2820

gactggagac agcattctat ttacaagaac ggctactgcc caaaccaccc cgtcattcag     2880

tggttctgga aggctgtgct actcatggac gccgaaaagc gtatccggtt actgcagttt     2940

gtcacaggga catcgcgagt acctatgaat ggatttgccg aactttatgg ttccaatggt     3000

cctcagctgt ttacaataga gcaatggggc agtcctgaga aactgcccag agctcacaca     3060

tgctttaatc gccttgactt acctccatat gaaacctttg aagatttacg agagaaactt     3120

ctcatggccg tggaaaatgc tcaaggattt gaaggggtgg attaagcacc ctgtgcctcg     3180

ggggtggttg ttcttcaagc aagttctgct tgcacttttg catttgccta acagactttt     3240

gcagaggcga tggcagagag cagctgcagg catggtccct ggagccgagc cttcaccacg     3300

cactcgtcca agttcggatg cgggaacctg gtcccagctt gagttcctgc ctttcccacc     3360

acaaattatc aactggttga tgtgtacact aattacattt caggaggact taatgctatt     3420

tatgttgtgc ctctgcaggc aaagccctta ataaatattt tacatccttt ctaatgacaa     3480

tgaatggaat taatcactca acaggtatag tattacgact catgtttact ttttaaaatg     3540

atttagaccg attttcagat tttatttcgt tatgattaaa gatgtctcat gtacttggaa     3600

aagtgagcat tttttttttt tttgtatttc actttcatac caggcttaat gtcaatgaca     3660

tttttatttt tgaagtactc tgacacctcc accctctact ttattagaat tggaaggcaa     3720

atttttgtcc aaaaacctac agacaagtac tttgagagaa tttccaatat aatattagac     3780

ataatgataa ttttttccat actcagaatg aaaaactgga tattacgttt ttgttttggg     3840

gtttttttgt acaaatttag ctaatagcta caggctgaga gaattgtaac atagcatgac     3900

aaattttgtg ttgacttgaa aggaatcaca ccattattcc ttagaagtaa ttacatgtgt     3960

tctaacacat ttgagacagg gttggactcc catttctcat ccgagaaatt acttaaccct     4020

tcctggcgct gtacagtcat cttttattct atttcctctt tgctgtttgt agtagagaca     4080

ttttgaatga aacttggcac tgcttgattc aaaactgtgg aaaccagatc tgtttagtct     4140

cctgtttgta tgcgtttgct aatggtagct aaataaccag tttttgttgt aaatgcacca     4200

attctgaagg cactttatgt actacatgga ggtcatatct ggttttgttt ttattttttt     4260

atcatgaaca ttaaatgtga tgatgatttc ttttccctgc acacatcttt ccggtgcaat     4320

atctatcaat tgtgaatctg gctgctggtg tataaaaacc tggatgtaaa gctgagccta     4380

cagacctgtc ctcaccaact gttttgtgat ttctactcaa ctacaaagat ttatttaatg     4440

tactcttaat ctaactgagt tttgttacca atgacctgtt gcatgcttca ataccgtgta     4500

ctgcctgagt tgtgcctctt gtgtgctaga ttaaaagtga gacagagact tgacttgatc     4560

ctctgagctc aagctattga gctggtagtg gcagaggact gagggtacct gcacagtttg     4620

attcttttcc acgtgtaagt ctccattgca gaattgtcgt gctttgagaa aacacctgag     4680

gcagtgtggg agttgaacga ccctgctgtc ctttttaacc tgtgttgtcc tagaccctgt     4740

cggggcagtc aggggacact agagatttga tctcatgcga gtcatcaata ggacaaaaaa     4800

gttgtggttt ggggaggtct gtttgttaca taaaaaggac ctttcggtgt aagaaattgc     4860

cgtttttacc ctgccctggc tggcatgtga gaagccatgg aaggttgtgg ttgtaaatga     4920

gttgtctaaa ggggtgcaga ggcctgaggt ttctaaaaga aggtagattt ctacagagct     4980

gagtgttggt tcctttttct tattggttga aaattacctg gtagtgatca gaaaacttag     5040

atgctatgta actaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ttcccgctca     5100

tgagttttga ctattggtga gatgttttcc gctacagtta acatgacaaa tgtctcagtg     5160

gcaaaaatcc cctttttgta agcccccata gtctagaggc agttttcttt ttaagaatca     5220

tgccagagcc tgagtcgagc agtatgcttt cttggttttt gagagtaatt gtgtaattgt     5280

agagggagaa atccaattct aacctaagaa ctgggattct tctgtcatct tgtaaaccgt     5340

atattgaaaa aaacagaatg tcactaaatg catattaagt caagtattgg aaagtataaa     5400

agaaaaatca ttctgacaat ttctaagcca gaagcaaaca agaattactg aaatctaccc     5460

catgaatact tggaaggcag taattgtgag tgacacctca gttcatcaac cccttaataa     5520

tatcagctta attttaatga caactaaata tgctgaagtg aggatttagt attttttaaa     5580

aaagcaaaac aaggttcagt agtcctcagc aattctccaa gtttctctct ttgcctaaaa     5640

tggtcataga tcttgatttc tctgaatcgt gatgaccaca cccagtcatc ttcacagcat     5700

aattgcaggt ggcagtaaag agagtgtgct gggtaaggag cagttgctgg gtcattcctt     5760

gggccccgac ctgcccgggg agtagccctg ggggagagag ggcagtgttg cctatcccag     5820

aggtcccagc agtcacactg ctctgcaggc cgggctctct ttatagccag agaaatcacc     5880

ttaatgcagt ctctttagtt gtctgctgaa gctgtagtta ttatgggcca cttacatgag     5940

gctgagaagt acgtgccgga gctcacacac tgcctgttgc ggttctctta acatcagtta     6000

tcacagctgc ctgtgggtcc cgggtatttc cattcctgcc ccttgttggc ccgaggaagg     6060

atgtggaaag agcacctggt gggatgaagg tccaacagcc tgtgcctctc cactgctggc     6120

cctggagccg gcagcagtga ggcattcatt gtctgtgttg cggtgtattc ccagcttcag     6180

tgctcttttc ctttttgcct gaaatgttta tgcttctctg cagccagtcc tctaacaaat     6240

ctcaagaaca aaggtaagac acttggtttt tgtttccagg acccttcaga aggtgacatc     6300

agatattccc taaattcaga caatgaggga tacagagcga cttggcatgt attatttctc     6360

ccatgtaagg acaaagggac agattattat tgttatttct gagacagagt cttgctctgt     6420

agctcaggct ggagtgcagt ggctcaatct cagctcacca caacctctgc ctcctggctt     6480

caagcgattc ttctgcctca gcctccccga atagttggga ttacaggcac ccaccaccac     6540

gcctggctaa tttttgtatt tttagtagag atggtttcac catgctggcc aggctggtct     6600

tgaactcctg acctcaggtg atcctcccgc ctcagccttc caaagtgctg ggattacaag     6660

catgagccac cgcacccggc ctcacagtga cagattctga gaaacagcat gcaaaacatt     6720

tgaaccattt tctacatctc ccattgttgc atagagagtg tgcaccgctg ctatcttgcc     6780

agatccacac tggtcctccc gaaagccagg ttcatacaca gcaacttttt aattattcta     6840

acagttaccc attaacagtc gactcctgta tttctgagag tcttgtactc acctctgaaa     6900

tttaaaaacg tataaagaga gcctgggtta atcagttctg cagcccctac gtgacactgt     6960

gctagttctc cttcttctgt ctcctcctta ccctggccct gcacccctgt acttaagagg     7020

gagaggtggg aggtgctgtc tggtatcatt tgctgcctcg ccagtagagg gtgccgctgt     7080

gcagggtaac tgcccgcctg ctcccttcct gacctcccct gaccccgaag atcactacct     7140

ctgtcattca ggcattgggg tacatcctga taagtcgtgt cagaactgcc aatttcagga     7200

ctgagatgtg tttttaaaaa acaaatcctt ataaactcca ctttgtactt tagattttaa     7260

aactggggaa aaatgtgata ttctttggac cactttttta atttatataa gccttaatga     7320

acagtgtcta tacatttgca tacacacacc cccaccccag agtgttctca gtatgtcaga     7380

gaaagtgcca cagcattagg acgggagctt ggagaacgtt ttctagaaaa gggttagctt     7440

cctgttggca tgaaattttc caagcaaacc tcattaaaca tctgttgttt gttaaagatg     7500

ttccactgaa agcaacgcat gtttcaaagg cacgtctttc cgttcgttgg ttttctgtgt     7560

gtaaggagta gcattgctgt tggcgcctaa cctcgcgtgc actgcattct caaccccgta     7620

ccagtgcatc atcagaagcc ttcctcgtga ccataactct gtgtctgcag atatgtgttc     7680

ccgtgtaagc cagttttccc cttttactca gactgatttc acctagattg tcacggtttc     7740

cttcatgtta actttgcgtg actttgttct tcctttacta ctctgtatgt aatatatata     7800

catatatacg tacatatgct gtccaaatat atttgtatat atttgtatag catttttaca     7860

cctttattga gtaatctggt ttcgaaagga ggtgagagtt tagtcccttc tgcagttttc     7920

tccaagctgt gtcctgtgaa tttcaaccct tggagcctaa gaaaacccta ggaagatgat     7980

gttaatttgc tgtcatttcc taattcagga tctatcatca aatgaaacat gaaaaaaaca     8040

gtgactttta aggtgaaaag agtttcaagc attccaaata aattatcaat gtttcataac     8100

tttttattat aaacccacct cctaatagga agccaagtac tatttgatac agtggtaaaa     8160

accaaactac cttgaatttt tttaaggcaa cttatgaata atgctcattt tcacagtcag     8220

aatagcttta aaatatggtt gaatttgata cacacaggaa gttttcttga agaacaatcc     8280

tttcgctttt cttttttctt gagagatcta aagagaaact gtagattgtt ttcctgacag     8340

caaaagacta atgtgacaaa atgaagtcat tgtaaagaag cgatgcaact tgtcaaatat     8400

ttaataaaga attatggaag ctggaacatt ttctac                               8436


<210>  633
<211>  6173
<212>  DNA
<213>  homo sapiens

<400>  633
agtgcggctg cgcgtgaggc ggcggcgcgc cggcgcgcga ggggcggggt gaaaggtcac       60

agcgcggcag cgggtctggc tggcggcagc ggcgggaggg agccgagaga cccgagtgca      120

cgtgtggaga agcggcggca caagcgcggc ggcgggagac actcccgccc ccaccagact      180

caagccctca ctcgactctc gcggccttcg ttgctcgcac agctccctgc ccaggctagg      240

aggccggctt gcggggttga gtggcccgag ctaagggtgc ggagacctaa gggcggcgac      300

tacgacggcg ttgatatcgg tggtaacgac ggcctcagca ggcggggaag atgaaaggta      360

gccggatcga gctgggagat gtgacaccac acaatattaa acagttgaaa agattgaatc      420

aggtcatctt tccagtcagc tacaatgaca agttctacaa ggatgtgctg gaggttggcg      480

agctagcaaa acttgcctat ttcaatgata ttgctgtagg tgcagtatgc tgtagggtgg      540

atcattcaca gaatcagaag agactttaca tcatgacact aggatgtctg gcaccttacc      600

gaaggctagg aataggaact aaaatgttaa atcatgtctt aaacatctgt gaaaaagatg      660

gtacttttga caacatttat ctgcatgtcc agatcagcaa tgagtcggca attgacttct      720

acaggaagtt tggctttgag attattgaga caaagaagaa ctactataag aggatagagc      780

ccgcagatgc tcatgtgctg cagaaaaacc tcaaagttcc ttctggtcag aatgcagatg      840

tgcaaaagac agacaactga acaaattaca aatgaacttt cttgcacttg cttgtcgcca      900

aataaaagag aggcccattg attcctcccc caccccaaca cttttctttt aaagcttttc      960

tccctccttg ttcttgtttt tctttcttcc tttccttttc tctgagagtt ttaatacttt     1020

caaggacttt aaaaaaataa tcatgtttga attgttttct cttatttttg tgaggtggtt     1080

tgaaggaagg acaaggtaga tctgtttagt tttgcagttg aagttagatg gtcctaaaca     1140

tttaattgtc aaataatttc aaatttaatg tcctgctttc acattgaagg gcagagccta     1200

caaaacattg tatatttcaa aagacaaaaa gaagcagcag cagtatcttg ttctctaatt     1260

catagacaag ttgagtgtgt ttgtggtact ttgggttttt aaacactttg ggatactaat     1320

ccctagacat tgccttcact ccacctttag tccttctgag cactctctcg ggagttggaa     1380

cattgttatc cttgtaagaa atactaagct tatgttgatt tttaagtaat tatatcttct     1440

cttcttgctg gtgggtgggg cagtttggtt tagtgttata ctttggtcta agtatttgag     1500

ttaaactgct tttttgctaa tgagtgggct ggttgttagc aggtttgttt ttcctgctgt     1560

tgattgttac tagtggcatt aacttttaga atttgggctg gtgagattaa ttttttttaa     1620

tatcccagct agagatatgg cctttaactg acctaaagag gtgtgttgtg atttaatttt     1680

ttcccgttcc tttttcttca gtaaacccaa caatagtcta accttaaaaa ttgagttgat     1740

gtccttatag gtcactaccc ctaaataaac ctgaagcagg tgttttctct tggacatact     1800

aaaaaatacc taaaaggaag cttagatggg ctgtgacaca aaaaattcaa ttactgtcat     1860

ctaatgccag ctgttaaaag tgtggccact gagcatttga ttttatagga aaaaatagta     1920

tttttgagaa taacatagct gtgctattgc acatctgttg gaggacatcc cagatttgct     1980

tatactcagt gcctgtgata ttgagtttaa ggatttgagg caggggtaat tattaaacat     2040

attgcttcta ttcttggaaa aatagaagtg taaaatgtta ataatacaaa tgtcactgtg     2100

acctcctcca ctgagaggac tggtttatgc cagatcattt tccggcacac acggagtggc     2160

tttgacagat tgataacttt gtaagatggg agacatctga aatattcatg ttttcctttt     2220

gtagtcccat ctccactatt tagaaatgtt ctcagacttt aaaataatgc acagggcttg     2280

agctttctgt catttgactt taaaaggaag tttcattcat atttatcctc ttatgtaaaa     2340

ttgcggtata aagtctcatt tccaaatatg ttaaatgaca aaattatttt ataaaatgtt     2400

tatgcacact ttataacctt aagtttttat ttgagaatgt gaaagtacaa agtgcagtag     2460

acttcaacaa tcttgagtgc caagaataat acagaaaaag aagacagttg atgaatgagt     2520

ttatagggtt ctaatcttaa gatggtaaaa atgtagaaag accttgctgg ttttttgggg     2580

gtattcgttt cttaaacaat ccaaatctaa gcttagaaga aaagtttagc gttaagcacc     2640

tttatcttca tgaataagct tcagcttgct cttggcaaga gaagagtgct tgagttacag     2700

aaggcataag tagtttgaag aatgcagcag cctttttgta aacttcccag atatcaaaat     2760

agactttgat atataaatgg ttttctgaga tgacactgcc tctatttcta taaccatttc     2820

acctggacta tctaatcagt cctatgaatg tatccctaaa tgtggttatt gaaaacctaa     2880

tagctgcctc atgacaagta catgttattt aaggaggaaa aaatattaaa ttttgaattg     2940

agtgtgtagg ctccctatca ttatatatag agtttctttt tccacggtag tcagtgactt     3000

aacctgaatt gtaaatgttt gtaaagggtt aattgtccta catcaaactt agttaaataa     3060

ttccatccac ttatggagga ggaggagaat gtggaagagg taaaaagctg ggcacaagtt     3120

catatgccta tgagtcagta aagactgaag taatgtccta tgttgagctg gttattttga     3180

tatatgataa taattatctt tgaagtagaa caattctgtt aactggaaaa tcacaggata     3240

tatccatcat atttttcagg acagatagtt tttactgtgg ggcaaatagg ttaaaattac     3300

actatgttag ttgcatttag gttttaaagc aaagaatctg tagagaaatc tatgcaatat     3360

atagtttgtc cagattagct ttcatttggg gaatgaagtt ctgaaatatc taaagcagtt     3420

tactcatcaa ttgaaaagtc ctccaaaaag agaactattg ggaaaccatg gtgtggtggt     3480

ggaaaagaaa agctccctca gttttttgga gggaataact taaaaaaata cttaaatggc     3540

taagtttact tggtgcagtt aagaattaaa cttgtcaatt ttaacattgc tgttacatct     3600

gaaataaact tatgtgatgt tctggtagtg atctgtgata tctgtaaatg tcaaaactgt     3660

attgttgaat tctgcagcca gcaaccgtac atactcattg tgtagtgttt cccttactgc     3720

ttttatttac tttcacattt aagatctaat tttaaaatca ttaaaatagg ccaagtgtaa     3780

ttaaggcatc ctaattcaga tcttctgtga cttgctaggt acagtgccca atatctacaa     3840

ttcagttcca atgagaggga aaaagtaaga tccaaggaac tgtcttgctg ctgtattttt     3900

aatgtaatta ttagaaatac ttgacacttt aggctgcaat ctagttagta atgtttattg     3960

gctacagaca acatattcag gtgttttgtt tttcttcctt gtaaggaagg agtacggtag     4020

ttcaatgagt tgggaattgg cttttaagct ttttatcaaa catgaattta agattttttc     4080

tttaacagaa ttcagtattt aatatttcta gtcaaaattg ttataattag atttttgctt     4140

ttttcattta agaagcaatg agtgatcctt gtctagtgtg tctcagttat tactgtagtt     4200

taaaacaaca aacaagtatt accttccaca gttctggatc aggaatctag gagctgctta     4260

actgggtggt tctgtcttga gatctcagaa ggttgcagtc aagctgttag ccaggactgt     4320

accatcttga agcttgacaa ggctagagga gccatttcca agatgtcttg cttacgtggc     4380

tcttgggctt ctgttcctca ctgtgtgggt atcacacaca gtgcctgatg ctcacgtggc     4440

tcttgggctt cagttccttg ggcaccagtt gcctggtgga caactggtat gtggcttccc     4500

ctagagcagg tgatataaga aagtgagcag aaaccatact tttttatgac gtagcctcag     4560

gtgacattat ttctgccata ttccatgagt cacacagacc aaccattgaa tcagcttggt     4620

atagtgtggg aggggactgc acaaggatgt gaatactggg aggtggatat cattgggccc     4680

tctaggagac tggctatcac tgctcagaga agatgctggg cttcgttgac tcccaaggtc     4740

agggtagttt tggttaggtt gtgttttatt agtctctaaa aggagtagtt ttctaaatga     4800

gggttataaa gcactgcact ttacagttat tcgggatata aaagaaatag tgggtctaaa     4860

ggctgtgctc ttgtggttgg gttttcagtg gggaggggag actagtctgt ctcagactga     4920

tgctgttctc actgatttga atatttctgg gaaattggat actacagtca caaataggaa     4980

cagtaagcct atagaagttt ttcagggagt aaatattttc tatggcagtg tcctgaattg     5040

gttctccctt gcaagactga actgtaggaa cttagtccta gtttatgata cagccaagta     5100

acatagtcac atgggaaaaa gagcttgagt cagatttctt aatgtgtgtt gttaacttgg     5160

tagaacattg agaattattt aagtcagaga acgatctgtt actggggcag aaattctcaa     5220

ccttttcagt tctccaaaat ttaagatact tgatttctta ggtaaaatgt ttttgttttt     5280

gttttggaga cagagtctcg ctctgtcgcc caggctggag tgcagtggcg cgatcttggc     5340

tcactgcaaa ctccgcctcc cagattcaag caattctgcc tgagcctccc aagtagctgc     5400

gactagaaag cgcatgccac cacgcctggc taattttttg tattttagta gagatggggg     5460

tttcaccgtg ttgcccaggc tggtctcaaa ctcctgagct taggcaatcc tcctggggca     5520

gcctcccaaa gtgctaggat tacaggcgag ccatggcgcc tggccagtaa aatgttttct     5580

atctagaatg aatcaaggta ttttccttgc tcagtagctt ctagaataag aaaaaaatag     5640

cagcaagatc tgattcagaa atagttggga gcagaaagtt aatatgaagg agttgctact     5700

tgttaacagc ctagagttga gatctagaag aattattacc tttttaaatt tgtgatgaaa     5760

gcttaaatcc agcatttggg aagttactct attggctgaa ctattttgga gtttgtaagc     5820

tttgtattag atattcctga tttaactgaa actaatttgc cacatagctt taatttcatc     5880

ccagttttac ttgttttact gtcctcaaaa actcaagaca tctgaactca aaggatctaa     5940

gcagtataaa ttaaagcaca tgttgaatca ctgtagcttt cgtaggacat ctgattataa     6000

tgcttttctt tgtttctttg tccatactga acttgtctag tttatctttg agaaacattt     6060

gctagtatca aaaatcttct gtaaagattt gaacaatctt gaattctcct tgtcactagc     6120

catctcttcc cctaaagtat aataaaactg tcaggtacta aaaaaaaaaa aaa            6173


<210>  634
<211>  9774
<212>  DNA
<213>  homo sapiens

<400>  634
agatgcaggg aagttttgcc tcttcctgaa aattatatta ttagcttttt aaaaatcagg       60

atgactgcta gttttgttta aagtatttgt tctggaaata ctaaagttgg agtctaccag      120

actgaggtta gaagcatttt ctttggcagc aagaagataa ttttatagaa gccatgcctg      180

ttcttggggt tgcctcaaaa ctgaggcagc cagctgttgg gtcaaagcct gtgcatactg      240

ctcttccgat accaaatctt ggcactactg ggtcacagca ctgttcttca agacctttgg      300

aacttactga aacagagagc tccatgcttt cttgtcagct tgcgttaaaa tcaacctgtg      360

aatttggaga gaagaaaccc ctccaaggaa aagccaagga gaaagaagac agcaagattt      420

acactgactg ggccaaccac tacctagcaa aatcaggcca caagcggctg atcaaggact      480

tgcaacaaga cattgcagat ggagtactcc tagcagaaat catccagatt attgcaaatg      540

aaaaagttga agatatcaat ggatgtccta gaagtcagtc tcagatgatt gaaaatgttg      600

atgtctgcct tagttttcta gcagccagag gggtaaatgt tcaaggtcta tctgctgaag      660

aaataagaaa tggaaactta aaagccattc tagggctgtt tttcagttta tctcgctaca      720

agcagcaaca acaccatcaa caacagtact atcagtcctt ggtggaactt cagcagcgag      780

ttactcacgc ttcccctcca tcggaagcca gccaggccaa aacccagcaa gatatgcagt      840

ccagtctggc agccagatat gcaactcagt ctaatcacag tggaattgca accagtcaaa      900

aaaagcctac taggcttcca gggccctcta gggtgcctgc tgcaggaagc agcagcaagg      960

tccagggagc ctctaattta aataggagaa gtcagagctt taacagcatt gacaaaaaca     1020

agcctccaaa ttatgcaaat ggaaacgaaa aagattcctc caaaggacct caatcgtctt     1080

caggtgtaaa tggtaacgtg cagcctccca gtactgctgg gcagcctcct gcctctgcca     1140

tcccttctcc aagtgccagc aagccctggc gcagcaagtc catgaatgtc aaacacagtg     1200

ccacctccac catgttgact gtaaagcagt caagtacagc cacctccccc acaccatctt     1260

cagacagact gaagccacct gtctcagaag gggtcaaaac tgctccctca ggacagaaat     1320

ccatgcttga gaaattcaag ctagtcaatg cccggactgc tttacgcccc ccgcagcctc     1380

ccagttcagg acctagtgat ggtgggaagg atgatgatgc cttttctgaa tctggtgaaa     1440

tggaaggttt taacagtggt ctgaatagtg gtggctcaac aaatagcagt cccaaagtgt     1500

cacctaagtt ggcccctcca aaagctggaa gcaaaaatct cagcaataaa aagtctttgc     1560

tacagccaaa ggaaaaagaa gaaaagaaca gggacaaaaa taaagtttgc actgaaaaac     1620

cagtcaaaga agagaaggat caggtgacag agatggctcc aaaaaagacc tccaaaattg     1680

caagcttgat ccctaagggc agcaagacaa cagcagctaa gaaggaaagc ttaattccgt     1740

cttccagtgg tattccaaaa ccaggctcta aagttccaac agtaaagcaa accatttcac     1800

ctggcagcac agcaagcaaa gagtctgaga aattcaggac taccaagggg agcccttccc     1860

agtccttatc taagcctata accatggaga aagcaagtgc ttctagttgt cctgcccctt     1920

tggaaggaag ggaagctggc caagcttctc cttctggttc ctgtaccatg acagtggcac     1980

aaagcagtgg gcagagcaca ggaaatggtg ctgtccaact ccctcaacag cagcaacata     2040

gccacccgaa taccgcgaca gtggcaccat tcatttacag ggcacattca gaaaatgaag     2100

gtaccgcttt accatcggct gactcctgta ccagtcctac aaagatggac ttatcatata     2160

gtaagactgc taagcagtgc ctggaggaga tatctggtga agaccctgaa acaagaagaa     2220

tgagaacagt taaaaacata gcagacttga ggcagaattt agaagagact atgtccagtc     2280

ttcgtgggac tcagataagc cacagcaccc tggagacaac atttgacagc actgtgacaa     2340

cagaagttaa tggaaggacc atacccaact tgacaagtcg acccaccccc atgacctgga     2400

ggttgggcca ggcatgtccg cgacttcagg cgggagatgc tccctccctg ggtgctggct     2460

atcctcgcag tggtaccagt cgattcatcc acacagaccc ctcgaggttc atgtatacca     2520

cgcctctccg tcgagctgct gtctctaggc tgggaaacat gtcacagatt gacatgagtg     2580

agaaagcaag cagtgacctg gacatgtctt ctgaggtcga tgtgggtgga tatatgagtg     2640

atggtgatat ccttgggaaa agtctcagga ctgatgacat caacagtggg tacatgacag     2700

atggaggact taacctatat actagaagtc tgaaccgaat accagacaca gcaacttccc     2760

gggacatcat ccagagaggg gttcacgatg tgacagtgga tgcagacagc tgggatgaca     2820

gcagttcagt gagcagtggt ctcagtgaca cccttgataa catcagcact gatgacctga     2880

acaccacatc ctctgtcagc tcttactcca acatcaccgt cccctctagg aagaatactc     2940

agctgaggac agattcagag aaacgctcca ccacagacga gacctgggat agtcctgagg     3000

aactgaaaaa accagaagaa gattttgaca gccatgggga tgctggtggc aagtggaaga     3060

ctgtgtcctc tggacttcct gaagaccccg agaaggcagg gcagaaagct tccctgtctg     3120

tttcacagac aggttcctgg agaagaggca tgtctgccca aggaggggcg ccatctaggc     3180

agaaagctgg aacaagtgca ctcaaaacac ccgggaaaac cgatgatgcc aaagcttctg     3240

agaaaggaaa agctccccta aaaggatcat ctctacaaag atctccttca gatgcaggaa     3300

aaagcagtgg agatgaaggg aaaaagcccc cctcaggcat tggaagatcg actgccacca     3360

gctcctttgg ctttaagaaa ccaagtggag tagggtcatc tgccatgatc accagcagtg     3420

gagcaaccat aacaagtggc tctgcaacac tgggtaaaat tccaaaatct gctgccattg     3480

gcgggaagtc aaatgcaggg agaaaaacca gtttggacgg ttcacagaat caggatgatg     3540

ttgtgctgca tgttagctca aagactaccc tacaatatcg cagcttgccc cgcccttcaa     3600

aatccagcac cagtggcatt cctggccgag gaggccacag atccagtacc agcagtattg     3660

attccaacgt cagcagcaag tctgctgggg ccaccacctc gaaactgaga gaaccaacta     3720

aaattgggtc agggcgctcg agtcctgtca ccgtcaacca aacagacaag gaaaaggaaa     3780

aagtagcagt ctcagattca gaaagtgttt ctttgtcagg ttcccccaaa tccagcccca     3840

cctctgccag cgcctgtggt gcacaaggtc tcaggcagcc aggatccaag tatccagata     3900

ttgcctcacc cacatttcga aggttgtttg gtgccaaggc aggtggcaaa tctgcctctg     3960

cacctaatac tgagggtgtg aaatcttcct cagtaatgcc cagccctagt accacattag     4020

cgcggcaagg cagtctggag tcaccgtcgt ccggtacggg cagcatgggc agtgctggtg     4080

ggctaagcgg cagcagcagc cctctcttca ataaaccctc agacttaact acagatgtta     4140

taagcttaag tcactcgttg gcctccagcc cagcatcggt tcactctttc acatcaggtg     4200

gtctcgtgtg ggctgccaat atgagcagtt cctctgcagg cagcaaggat actccgagct     4260

accagtccat gactagcctc cacacgagct ctgagtccat tgacctcccc ctcagccatc     4320

atggctcctt gtctggactg accacaggca ctcacgaggt ccagagcctg ctcatgagaa     4380

cgggtagtgt gagatctact ctctcagaaa gcatgcagct tgacagaaat acactaccca     4440

aaaagggact aagatatacc ccatcatctc ggcaggccaa ccaagaagag ggcaaagagt     4500

ggttgcgttc tcattctact ggagggcttc aggacactgg caaccagtca cctctggttt     4560

ccccttctgc catgtcatct tctgcagctg gaaaatacca cttttctaac ttggtgagcc     4620

caacaaattt gtctcagttt aaccttcccg ggcccagcat gatgcgctca aacagcatcc     4680

cagcccaaga ctcttccttc gatctctatg atgactccca gctttgtggg agtgccactt     4740

ctctggagga aagacctcgt gccatcagtc attcgggctc attcagagac agcatggaag     4800

aagttcatgg ctcttcatta tcactggtgt ccagcacttc ttctctttac tctacagctg     4860

aagaaaaggc tcattcagag caaatccata aactgcggag agagctggtt gcatcacaag     4920

aaaaagttgc taccctcaca tctcagcttt cagcaaatgc tcaccttgta gcagcttttg     4980

aaaagagctt agggaatatg actggccgat tgcaaagtct aactatgaca gcggaacaaa     5040

aggaatctga acttatagaa ctaagagaaa ccattgaaat gctgaaggct cagaattctg     5100

ctgcccaggc ggctattcag ggagcactga atggtccaga ccatcctccc aaagatcttc     5160

gcatcagaag acagcattcc tctgaaagtg tttctagtat caacagtgcc acaagccatt     5220

ccagtattgg cagtggtaat gatgccgact ccaagaagaa gaaaaagaaa aactgggtga     5280

actctagagg aagtgagctg agaagttctt tcaaacaagc ctttgggaag aaaaagtcca     5340

ccaagcctcc ttcatcacat tctgacattg aagagcttac tgattcatcc cttccggcat     5400

cccccaagtt accccataat gctggtgact gtggctcagc atccatgaag ccctcacaat     5460

ctgcttcagc gatctgtgaa tgcacagaag ctgaggcaga gataattctg cagctgaaga     5520

gcgagctcag agaaaaggaa ttaaaattaa cggatattcg gctggaggcc ctcagctctg     5580

ctcatcatct tgatcagatc cgggaagcca tgaaccggat gcagaatgaa attgaaatac     5640

tgaaagctga aaatgaccgg ttgaaggcag aaactggtaa cacagctaag cctactcggc     5700

caccgtcaga atcctcaagc agcacctcct cttcatcttc caggcagtca ttaggacttt     5760

ctctaaacaa tttgaacatc acagaggctg ttagctcaga tattttgcta gatgatgctg     5820

gtgatgcaac tggacataaa gatggccgca gtgtgaaaat tatagtctcc ataagcaagg     5880

gctatggtcg agcaaaggac caaaaatctc aggcatattt gataggatcc attggtgtta     5940

gtggaaaaac caagtgggat gtcttagatg gtgtaataag acgtctcttt aaggaatatg     6000

tattccgaat tgatacatcc actagccttg gtctgagctc tgactgcatt gctagctact     6060

gtataggaga cttaattaga tcccataacc tagaagtgcc tgaattgctg ccttgtggat     6120

accttgttgg agataataac atcatcactg tgaacctcaa aggggtagaa gaaaatagtt     6180

tggacagttt tgtttttgat acgctgattc ctaaaccaat tacccaaagg tactttaact     6240

tgttgatgga gcatcacaga attatactct caggaccgag tggtactgga aagacctatt     6300

tggcaaacaa acttgctgaa tatgtaataa ccaaatctgg aaggaaaaaa acagaggatg     6360

caattgccac ttttaatgtg gaccacaagt caagtaagga attgcaacaa tatctagcta     6420

acctggctga acagtgcagt gctgataata atggagtgga gctcccagtt gtaataattc     6480

ttgataatct tcatcatgtg ggctctctga gtgatatctt caatggtttt ctcaattgta     6540

aatacaacaa atgtccatat attattggaa caatgaatca gggagtttct tcatcaccaa     6600

atctagagct gcatcacaat ttcaggtggg tattatgtgc aaatcataca gaaccagtga     6660

aaggcttttt aggcagatat cttcgaagaa aactcataga gatagaaatt gaaaggaaca     6720

ttcgcaataa tgacctagtc aaaattatag attggattcc gaagacgtgg catcatctca     6780

acagtttttt ggaaacacac agttcttctg acgttaccat tggtccccga ctattccttc     6840

cttgccccat ggatgtagaa ggttctagag tatggttcat ggatctctgg aactattctt     6900

tagtacctta tattctggag gcagtgagag agggtcttca gatgtatggg aaacgcacac     6960

catgggaaga tccttcaaag tgggtgcttg acacatatcc atggagctca gcaactctgc     7020

ctcaggagag cccagcctta cttcagctgc gaccagaaga tgttgggtat gaaagctgca     7080

catccactaa ggaagccaca acctcaaagc acattccgca aactgacaca gaaggagatc     7140

ccctgatgaa tatgctaatg aaactccaag aagcagccaa ttactcgagc acacaaagct     7200

gcgacagcga aagcaccagc caccatgaag acattttgga ttcatctctt gaatctaccc     7260

tctagagggt gaaaaaagtt aagggaaaag actttgcttt taaaaaaatg tttcaaaaga     7320

aaggtatttt cactaaacca ctgccagtat aaaagcaccc tgtcaagggc cctgacccag     7380

agttgtggtc tccaaggagg cagcagaact aagtctgaac cgccaagatg ctaaattgca     7440

atggaagctt aactttagtt tatttctaag cattttttat atctgtggag taatagaaag     7500

ctccattact caactggaaa ggaccctaat gacagggcaa ctgaacagat tgcacatggg     7560

atagccaaac tggactttct ttgtttcctc tttaaaagtt tacaatgcag accatttttt     7620

gtcccttcct tttgtttcct ctgaggggct gttcgcccca ggcagggtcc atctttctga     7680

tctgtccaac ctcctttgtg ccacacggtg ctggtcacag ggcttcagta gtgtttgtgt     7740

tgtgcgctca ccccattcca gaacaaatcc aagaggccag tcctccataa gcacaaatgg     7800

aattgtgcaa ccaccagaaa aacactactg tggcaaactg gagaagtgcc aatttaattc     7860

taactgccac gttctcatga tgtgctccac caacttttta gtatatgagt cactggtttt     7920

ataaggttgt ttttaccaca gtggtctttt taaaccacct gcccactccc ttaacaagag     7980

ttttatacca attattagtc aacactgata aaaggctttt ttagggcttt atttgtttga     8040

gccttttcag tgaaagaagg aacatttcct atggtgctgt ctcactgcct taaaacagat     8100

ttctatgaca gtttaacagt tggtttaaat cctaaaccat tggtaatttc cactgtcttt     8160

tcatttacaa ccaagcaaca ccagttaaca tagtagcctc atctctatat atctttctct     8220

tttttttttt tttgaagaaa tggataggag aaagatcagt atttttagcc ttgtgaatag     8280

atcgctttgc ctatcctcca aaatattaaa ataacccaga aatgctcttt gaccgtcact     8340

taaaacctaa gacatgtggc gaaattccat ccagttctaa gtgaaagagt ttcagaaggc     8400

agaagatttt gaattattat ccagcagggc tggaagcact agatgcagca tgagcacaac     8460

tattcggctt tccttcccta ttgtttttgt ttttttaatg agttttgacg catgttgttt     8520

tgattgctat tgttgtacat gagaaattca gcattaaaga acactgaagc ggtaaggtca     8580

ctgtggaaga ggaagcgttt atactgtaaa agaaggttag atttgcacag tctactgggt     8640

aggtattgta aataataatt tttaaaactt gcacaaatca aaacaaacac aaacaaaatt     8700

gtattttatc ctgttggtgt taagaggtgt ttcacttgct gagatttcct gtacattgca     8760

aacaaataca gaatgcaaac cctcaaagct gtattatctg gtgtgtttgt cctgtattta     8820

cagttgtttt tgactatgca ggagctatca gtgctagagt gagcatgctt caaaactgta     8880

catgaagcca atatattttt ggataagtaa aactgtctga aagtacatct gtcatggcag     8940

gctttaaaga gagtgcatga aaactgatca gtcattggag aagttaccac cacacacaaa     9000

ggacaggttt taagtttatg aaacccaagg gctaggccat ggtatagact tcttctatga     9060

gtgtgtgaaa atgtgttact tttaggacgt gtatttggtg ctactctctg tgaccaccaa     9120

tgggtcagtt gctatagaac aacaacacca cgaaacatct gtgcagtttt cagagtgtca     9180

caaagtcaat aggtccttac acggtgctat tgccctaagg gaaatccgaa ctgaatttat     9240

gcacatagaa ttgtcaccct gactttgaag cctcaaacat ggatcaaatc tgttgtgaaa     9300

catcaatata tgtagctgga tgagtgacta gtttcccttg tataatatgt gatctaagaa     9360

aattgctaat ctttccctgc cattttgaga aacacagtcc aaacatgagc ataaacagaa     9420

tttcctgcaa tacatcccag taggtccacc tagtttacaa cttaaactag tttgtgaaac     9480

atttgtctgt atacatttta tattttgtac attttgatgt aacatatcat gtaaataggc     9540

agaaacagtg aaataaatca tctgaaaagt tttgtagtct ttgtaaagcc ccaacaataa     9600

gtacttggtg tcaatggact taactggatg atgtattttc tattggttta ttgttcctct     9660

agcttgtaaa ccagcttgca tatatttttt tgcaaatgtg caccctgtat ctgtctaaat     9720

tattactttg ccattaaagt ggaattattt attgacaaca aaaaaaaaaa aaaa           9774


<210>  635
<211>  10017
<212>  DNA
<213>  homo sapiens

<400>  635
ttcctccgcg aaggctcctt tgatattaat agtgttggtg tcttgaaact gacgtaatgc       60

gcggagactg aggtcctgac aagcgataac atttctgata aagacccgat cttactgcaa      120

tctctagcgt cctctttttt ggtgctgctg gtttctccag acctcgcgtc ctctcgattg      180

ctctctcgcc ttcctatttc tttttttttt ttttaaacaa aaaacaacac cccctcccct      240

ctcccacccg gcaccgggca catccttgct ctatttcctt tctctttctc tctctctctc      300

tctctctctc ttttttaata agggtggggg agggaaaggg gggggaggca ggaaagacct      360

ttttctctcc cccccgcaat aatccaagat caactctgca aacaacagaa gacggttcat      420

ggctttggcc gccgcgccac catctttcgg gctgccgagg gtgttcttga cgattaatca      480

acagatgtac agatcagctc tcaaaatgtc ttctgtgtct tctgagcgtc ttctaagaca      540

attgcattag cctcctgcta gttgactaat agaattaata attgtaaaaa gcactctaaa      600

gccacatgcc ttatgaagtc aatgctgggt atgattttac aaatatggtc cggaaaaaga      660

acccccctct gagaaacgtt gcaagtgaag gcgagggcca gatcctggag cctataggta      720

cagaaagcaa ggtatctgga aagaacaaag aattttctgc agatcagatg tcagaaaata      780

cggatcagag tgatgctgca gaactaaatc ataaggagga acatagcttg catgttcaag      840

atccatcttc tagcagtaag aaggacttga aaagcgcagt tctgagtgag aaggctggct      900

tcaattatga aagccccagt aagggaggaa actttccctc ctttccgcat gatgaggtga      960

cagacagaaa tatgttggct ttctcatctc cagctgctgg gggagtctgt gagcccttga     1020

agtctccgca aagagcagag gcagatgacc ctcaagatat ggcctgcacc ccctcagggg     1080

actcactgga gacaaaggaa gatcagaaga tgtcaccaaa ggctacagag gaaacagggc     1140

aagcacagag tggtcaagcc aattgtcaag gtttgagccc agtttcagtg gcctcaaaaa     1200

acccacaagt gccttcagat gggggtgtaa gactgaataa atccaaaact gacttactgg     1260

tgaatgacaa cccagacccg gcacctctgt ctccagagct tcaggacttt aaatgcaata     1320

tctgtggata tggttactac ggcaacgacc ccacagatct gattaagcac ttccgaaagt     1380

atcacttagg actgcataac cgcaccaggc aagatgctga gctggacagc aaaatcttgg     1440

cccttcataa catggtgcag ttcagccatt ccaaagactt ccagaaggtc aaccgttctg     1500

tgttttctgg tgtgctgcag gacatcaatt cttcaaggcc tgttttacta aatgggacct     1560

atgatgtgca ggtgacttca ggtggaacat tcattggcat tggacggaaa acaccagatt     1620

gccaagggaa caccaagtat ttccgctgta aattctgcaa tttcacttat atgggcaact     1680

catccaccga attagaacaa cattttcttc agactcaccc aaacaaaata aaagcttctc     1740

tcccctcctc tgaggttgca aaaccttcag agaaaaactc taacaagtcc atccctgcac     1800

ttcaatccag tgattctgga gacttgggaa aatggcagga caagataaca gtcaaagcag     1860

gagatgacac tcctgttggg tactcagtgc ccataaagcc cctcgattcc tctagacaaa     1920

atggtacaga ggccaccagt tactactggt gtaaattttg tagtttcagc tgtgagtcat     1980

ctagctcact taaactgcta gaacattatg gcaagcagca cggagcagtg cagtcaggcg     2040

gccttaatcc agagttaaat gataagcttt ccaggggctc tgtcattaat cagaatgatc     2100

tagccaaaag ttcagaagga gagacaatga ccaagacaga caagagctcg agtggggcta     2160

aaaagaagga cttctccagc aagggagccg aggataatat ggtaacgagc tataattgtc     2220

agttctgtga cttccgatat tccaaaagcc atggccctga tgtaattgta gtggggccac     2280

ttctccgtca ttatcaacag ctccataaca ttcacaagtg taccattaaa cactgtccat     2340

tctgtcccag aggactttgc agcccagaaa agcaccttgg agaaattact tatccgtttg     2400

cttgtagaaa aagtaattgt tcccactgtg cactcttgct tctgcacttg tctcctgggg     2460

cggctggaag ctcgcgagtc aaacatcagt gccatcagtg ttcattcacc acccctgacg     2520

tagatgtact cctctttcac tatgaaagtg tgcatgagtc ccaagcatcg gatgtcaaac     2580

aagaagcaaa tcacctgcaa ggatcggatg ggcagcagtc tgtcaaggaa agcaaagaac     2640

actcatgtac caaatgtgat tttattaccc aagtggaaga agagatttcc cgacactaca     2700

ggagagcaca cagctgctac aaatgccgtc agtgcagttt tacagctgcc gatactcagt     2760

cactactgga gcacttcaac actgttcact gccaggaaca ggacatcact acagccaacg     2820

gcgaagagga cggtcatgcc atatccacca tcaaagagga gcccaaaatt gacttcaggg     2880

tctacaatct gctaactcca gactctaaaa tgggagagcc agtttctgag agtgtggtga     2940

agagagagaa gctggaagag aaggacgggc tcaaagagaa agtttggacc gagagttcca     3000

gtgatgacct tcgcaatgtg acttggagag gggcagacat cctgcggggg agtccgtcat     3060

acacccaagc aagcctgggg ctgctgacgc ctgtgtctgg cacccaagag cagacaaaga     3120

ctctaaggga tagtcccaat gtggaggccg cccatctggc gcgacctatt tatggcttgg     3180

ctgtggaaac caagggattc ctgcaggggg cgccagctgg cggagagaag tctggggccc     3240

tcccccagca gtatcctgca tcgggagaaa acaagtccaa ggatgaatcc cagtccctgt     3300

tacggaggcg tagaggctcc ggtgtttttt gtgccaattg cctgaccaca aagacctctc     3360

tctggcgaaa gaatgcaaat ggcggatatg tatgcaacgc gtgtggcctc taccagaagc     3420

ttcactcgac tcccaggcct ttaaacatca ttaaacaaaa caacggtgag cagattatta     3480

ggaggagaac aagaaagcgc cttaacccag aggcacttca ggctgagcag ctcaacaaac     3540

agcagagggg cagcaatgag gagcaagtca atggaagccc gttagagagg aggtcagaag     3600

atcatctaac tgaaagtcac cagagagaaa ttccactccc cagcctaagt aaatacgaag     3660

cccagggttc attgactaaa agccattctg ctcagcagcc agtcctggtc agccaaactc     3720

tggatattca caaaaggatg caacctttgc acattcagat aaaaagtcct caggaaagta     3780

ctggagatcc aggaaatagt tcatccgtat ctgaagggaa aggaagttct gagagaggca     3840

gtcctataga aaagtacatg agacctgcga aacacccaaa ttattcacca ccaggcagcc     3900

ctattgaaaa gtaccagtac ccactttttg gacttccctt tgtacataat gacttccaga     3960

gtgaagctga ttggctgcgg ttctggagta aatataagct ctccgttcct gggaatccgc     4020

actacttgag tcacgtgcct ggcctaccaa atccttgcca aaactatgtg ccttatccca     4080

ccttcaatct gcctcctcat ttttcagctg ttggatcaga caatgacatt cctctagatt     4140

tggcgatcaa gcattccaga cctgggccaa ctgcaaacgg tgcctccaag gagaaaacga     4200

aggcaccacc aaatgtaaaa aatgaaggtc ccttgaatgt agtaaaaaca gagaaagttg     4260

atagaagtac tcaagatgaa ctttcaacaa aatgtgtgca ctgtggcatt gtctttctgg     4320

atgaagtgat gtatgctttg catatgagtt gccatggtga cagtggacct ttccagtgca     4380

gcatatgcca gcatctttgc acggacaaat atgacttcac aacacatatc cagaggggcc     4440

tgcataggaa caatgcacaa gtggaaaaaa atggaaaacc taaagagtaa aaccttagca     4500

cttagcacaa ttaaatagaa ataggttttc ttgatgggaa ttcaatagct tgtaatgtct     4560

tatgaagacc tattaaaaaa atacttcata gagcctgcct tatccaacat gaaattccct     4620

tcttttgtta ttctttcttt tgatgagtag gttaccaaga ttaaaaagtg agataaatgg     4680

tcaatgagaa agaatggaag atggtaaaca atcacttttt aaaacctgtt aagtcaaaac     4740

catcttggct aatatgtact ggggaaataa tccataagag atatcaccag actagaatta     4800

atatatttat aaagaaagag accaaaactg tctagaattt gaaagggttt acatattatt     4860

atactaaagc agtactggac tggccattgg accatttgtt ccaaaaccca taaattgttg     4920

cctaaattta taatgatcat gaaaccctag gcagaggagg agaaattgaa ggtccagggc     4980

aatgaaagaa aaatggcgcc ctctcaattt agtcttctct cattggccat gtttcagatt     5040

ttgacctaga aatgcgagct gtggttaggc ttggttagag tgcagcaagc aacatgacag     5100

atggtggcac gctgttttta cccagccctg cctgtacata cacatgcaca ccctctctga     5160

tatttttgtc ctttagatgt tcaaatactc agtagtcctt ttgtttgcgg tttagattca     5220

ttttgtccac acatgtaccc attttaaaaa acaatgtcct cgatgcttct gtagtgattt     5280

cattttagcc aggtatttct ttcttgtgtg tgatgaacca gtatggattt gcttttctaa     5340

gcctcctgtt ggttactaat ctcacttggc acattataac taaaggaatc ccctcaattc     5400

aaaagcatag atggatacaa atgtcagacc gtgggtttaa tttgtttaga acacatggca     5460

tttcttcaca aggtaacctg ctgtatttat ttattttctt ttggttaaat ataatttcca     5520

aactttgtgg tcaggcagcg tctaaggtta cgttaccaca gactgacagt tggtatatgt     5580

accagccaat cccttcatta aatgtataca gatttagtta agtagcatta aataggattc     5640

ttagaagtat gtcctcatag aacttttaat acttaaggct ttgtaaaaac tatccatgaa     5700

gggaaagctc ctcagcataa ctgctcaggg aaatagggct aaataactga acattaaata     5760

attggttaaa ggtgctgtta gtcgagcctc aatgcttgct acaaggatgt atgtacaagg     5820

actgacttta ataatttgca ttatattgtc ccaaccagta gtttattttt tgccacggag     5880

atgtagaaga tattacaagc tactggatgc actgtcagat taacttattt cattaaagaa     5940

gttgggagaa caaataggaa aaaaaaaact tatttttcta gtaaatatta atgtattaca     6000

tttcaaataa tggtgcctga catattgaat aattattttc tacagtgtac gtatgcaaca     6060

aagatattcc atcatgcatt agagtcagtt ctggctctgc ctagctgttt acatttgcaa     6120

atgtagcaaa caaggtaatg aagcaactat ttctattgca gtagatatcc ttttgtgtgt     6180

gtgtgtgtgc attaaagttg taaacggtaa catgaaacaa atgaaagttc ttgctataat     6240

ggtatggaaa acaagaagga aatgaaaata tttttatgcc tacttaggaa aaaaagggta     6300

gcacttattc attccaagta cttttttttt tttaattttt aagctcttaa ctcacattgt     6360

tatgcttaag atgataaaca tatatcctct ttttattgct ttgtctatgt ttcatatgaa     6420

acatttcaga aattattttg ataagtgttg ctggaatctg caacgctgat ttttttttgc     6480

attctgtagt cgcatttgca ctccattttt acattaattc gcagttgctt tgtatcattg     6540

ttttgtttgg gttttgtttc tttttcacag tgccgggtct tcgtttctta aagttggatg     6600

gcaggtagag ttcaaccagt tcgtgactgt tgtagcgaat gaagttaaaa aaatgtcttt     6660

ctgatgttgt gttgtcattt tcatttttgc atttttttgt ttgcatatta aaaaaagaga     6720

aaagagaaag caagagacag aaatcaggac taagtcctct gcttcagttt cattgttaac     6780

gggccttatt ctgatctcac ctgtcgcgta gctctaatat tcacataaac tgaaataaag     6840

aagtggaatg aggagctttg acattcaaat tatgtgatgt aatttatctt ccttaggaat     6900

tttgatggat gcatctcaaa atgtatagcc agacttgaga ggtgacaatt aaagatctaa     6960

aaaagagagg agattccccc aaacaacaat atttaatttt cttagtaaaa agaataacag     7020

aatgcatcgt ggcaatcctt aagcaacatt atctatgtgg actgcttaaa tcagcaaaac     7080

accagaagtt tggttaactt gggcaatatg acaagtatta ctttttgggc aaaactactc     7140

attaagcaat ttctctagtg tgtcggacac aaataggttc tttatttttg gcatgtatgc     7200

ctttttattt tcattcaatt tttttttttt ctcagacaga catagtagta acgactagca     7260

ttggaaaata catatcacta ttcttggaat atttatggtc agtctacttt ttagtagaat     7320

atttttggat agcgttgaca cgatagatct tattccatac ttctttatta ttgataattt     7380

tattttcatt ttttgctttc attattatac atattttggt ggagaagagg ttgggctttt     7440

ttgaaagaga caaaaattta ttataacact aaacactcct tttttgacat attaaagcct     7500

ttattccatc tctcaagata tattataaaa tttatttttt taatttaaga tttctgaatt     7560

attttatctt aaattgtgat tttaaacgag ctattatggt acggaacttt ttttaatgag     7620

gaatttcatg atgatttagg aattttctct cttggaaaag gcttcccctg tgatgaaaat     7680

gatgtgccag ctaaaattgt gtgccattta aaaactgaaa atattttaaa attatttgtc     7740

tatattctaa attgagcttt ggatcaaact ttaggccagg accagctcat gcgttctcat     7800

tcttcctttt ctcactcttt ctctcatcac tcacctctgt attcattctg ttgtttggga     7860

tagaaaaatc ataaagagcc aacccatctc agaacgttgt ggattgagag agacactaca     7920

tgactccaag tatatgagaa aaggacagag ctctaattga taactctgta gttcaaaagg     7980

aaaagagtat gcccaattct ctctacatga catattgaga ttttttttaa tcaactttta     8040

agatagtgat gttctgttct aaactgttct gttttagtga aggtagattt ttataaaaca     8100

agcatgggga ttcttttcta aggtaatatt aatgagaagg gaaaaaagta tctttaacag     8160

ctctttgttg aagcctgtgg tagcacatta tgtttataat tgcacatgtg cacataatct     8220

attatgatcc aatgcaaata cagctccaaa aatattaaat gtatatatat tttaaaatgc     8280

ctgaggaaat acatttttct taataaactg aagagtctca gtatggctat taaaataatt     8340

attagcctcc tgttgtgtgg ctgcaaaaca tcacaaagtg accggtcttg agacctgtga     8400

actgctgccc tgtttagtaa ataaaattaa tgcatttcta gagggggaat atctgccatc     8460

cagtggtgga aatgtggagt aaagaagctg gtggtctgct tctgtgctgt atgccagcct     8520

tttgccttaa gttgagagga ggtcaacttt agctactgtc tttggtttga gagccatggc     8580

aaaaaaaaaa aaagaaaaaa agatcaagtc gtctttggtg agccagtaag gtgaaagctt     8640

gctgactgtc caaggcacaa gagaaaattg aggaattgaa atgcaacctg agtatcaaac     8700

taaatattct aatcaaaggt aggtactgtt aggtggaatt ctatcagcag gcaactgcaa     8760

atgagaagaa gatagaagga cgcccgtcgg gactttggag ggcattgtta ttttcccaaa     8820

gaaagacggc caagggcaga ggcatggatt ctttgcagag cacttccttt tggtttttca     8880

gtactgtttc atagacagtg ggctcacatg ttcctgatag tgctgcagtt gcttagaaag     8940

catcccagtt aattgcagta attagaactt ctggaatatg ctagggcaga agtatgtcaa     9000

gtatgtcaca tgaagaaaat gtgaaattca agagtaatcc acacgtgaga aactagacaa     9060

tgtacattca tgtgttctct tgaaaggaaa gggagagctg taagcttcac tctgtcctac     9120

accggagaaa agcaggaata actttaccgt ggaaataatg tttagctttt atcagagaaa     9180

attgtccttc tagagcatag agtcccaaaa ctcaattctg gttttcccct gttttttttt     9240

tttttttttt tcccaacata taaactgcag catatcactt tttctttttg tgcctcaggt     9300

tcctcagctg taaaattgaa aaatatatgt attaataata ttattaataa taataatggt     9360

aatgtagtac ttgtttgtaa agcactttga gatccttggt tgaaaggcac cataggagtg     9420

ccaagtatta ttatgtggcc aagggggtta tttaaactgt cagttcccaa aggccaggaa     9480

aggttggggt catttttctt aaagacgagc tgtaaatatc aactaggcag ccaatagtgt     9540

tgactatgaa gatgcaaaac tattactagg ctgataaaat catagtttct taatggctac     9600

caataaggca aatatcacaa taataaacgc caaattcctt agggcggact atttgacaac     9660

cacatggaaa actttggggg aggcatgagg ggggaacatc tcaaaatgcc aatgtaaaat     9720

ttaacttaca gcaatattca ccagcagaaa atgtctttca tatggaatga tttcatgttg     9780

ctaagaaaaa gaattcaatt tgtagtcctg atttgaatac tagaatgttg gctataatag     9840

ttctgttctt acaacacatg aaattttttc gttttatttt attttgtttt catagtgcat     9900

gttcatttct actcacaaac atgttcttgg tgtatttctt atgcaaacaa tcttcaggca     9960

gcaaagatgt ctgttacatc taaacttgaa taataaagtt ttaccaccag ttacaca       10017


<210>  636
<211>  2667
<212>  DNA
<213>  homo sapiens

<400>  636
acgtgagagg agacttccgg ccactgcgtt gtagtcggcc cggctgcaaa gcgtttttct       60

gcaggctgtt ttcccaggtt ccctcggcct gtacctcgcg cactcctctt gctccaggtc      120

cttcagtctc cgctcgtctc accgtaggct gtgacgacat gagcaacaaa gaaggatcag      180

gagggttcag gaaaaggaag catgacaatt tcccacataa ccaaagaaga gaagggaagg      240

atgttaattc atcttcaccc gtgatgttgg cctttaaatc atttcagcag gaacttgatg      300

caaggcatga caaatatgag agacttgtga aacttagtcg ggatataact gttgaaagta      360

aaaggacaat ttttctcctc cataggatta caagtgctcc tgatatggaa gatatattga      420

ctgaatcaga aattaaattg gatggtgtca gacaaaagat attccaggta gcccaagagc      480

tatcagggga agatatgcat cagttccatc gagccattac tacaggacta caggaatatg      540

tggaagctgt ctcttttcaa cacttcatca aaacacgatc attaattagt atggatgaaa      600

ttaataaaca attgatattt acgactgaag acaatgggaa agaaaataaa actccctcct      660

ctgatgcaca ggataagcag tttggtactt ggagactgag agtcacacct gtcgattacc      720

ttctgggagt ggctgactta actggagaat tgatgcggat gtgtattaac agtgtgggga      780

atggggacat tgataccccc tttgaagtga gccagttttt acgtcaggtt tatgatgggt      840

tttcattcat tggcaacact ggaccttacg aggtttctaa gaagctgtat accttgaaac      900

aaagtttggc caaagtggag aatgcttgtt atgccttgaa agtcagaggg tcagaaattc      960

caaaacatat gttggcagat gtgttttcag ttaaaacaga aatgatagat caagaagagg     1020

gcatttctta gaatctaacg ttactcagtt actaattctt ttgagaactc ctaagagacc     1080

aatttgtaag acttatttag tatttcattt aactttattg tggcttttac atagaaacat     1140

attcagttgt acttgtttta aattgtatac aagctgtaca taaaattagc caaatgaatc     1200

atttcttata tcttattcat gaaagtttgc atacagatgt ttgcatatat gcctttttga     1260

atttttgctg gttaaccttt atcatttatc tttgtaatgt gaacatgctt cagagtgtac     1320

cttttgccat aacctatttt aatttacttt ttctgaagtt tggagtgata atttttagtg     1380

gaagcaattt gtaatttaag ttggtagtta tattatatat agaaaagatt ttttagttaa     1440

acttctggac atgagcgtcc tgtttaaatt tcttgttaat atcgtgccaa gcctcaaaaa     1500

taggcttatt ccatggaaca agaattaaaa atgaataagc tatcaatata taatttaagt     1560

acaagtttag gctgggcgtg gtggctcacg cctgtaatcc cagcactttg ggaggccgag     1620

gtaggcagat cacgaggtca agagatcaag accagcctga ccaacgtggc gaaacctcgt     1680

ctctactaga aatacaaaaa ttagctggat atggtggtat gtgcctgtaa tcccagctac     1740

ttgggaggct gaggcaggag actcgcttga acctgggagg cagaggttgc agtgagccga     1800

gattgcgcca ctgcactcca gcctgggtaa cagagcaaga ctccatctca aaaaaagaaa     1860

gaaagaaaaa agaaagtaca agtttataaa gtattatagt gaaaaattcg cattctggct     1920

gattttaagc catttaaaat ttatataaaa caaccttcca taaaaatttg acaggtgccc     1980

agatgttgct ttctccattt attttttgtt tttttttaat cacagtaggt ctgatagaga     2040

attggagcta aattataata tttttgttgg taaagttgag ttatatactt gtacatacaa     2100

tggaaatgct tttagtagtg attatttagc aatttttgtt tttgttatat taggcatgtt     2160

tggaggcttt cctattctag catttaaatt taaattttat taaaattaaa taatttaaat     2220

ctagcattta aatttaaata atttaagtct agcatttact tttaaataat tataatgaag     2280

ttttgaaata ctaagttaat ccagaccttt agttgtccca tggtgttaat aaagttgcca     2340

aagaagatgt attatgaaca attcagcaat aagacaattg tcaacacagt tgagaataac     2400

aatggtaatc gttagtaata tttagaattg gaatttgcct actgaaatag ttatagatga     2460

ttacttgtga tgtgaaactg aattgagcat gacaaccaga catttccagt tggttttgta     2520

agttttgaga atctagatac tgggttttat tttttgaaag attagctctg tttgtaaggg     2580

ctgattcctt gaaaatgtaa ttttccagaa aaacacctaa agaaaataaa acatggacat     2640

gcctagtaaa aaaaaaaaaa aaaaaaa                                         2667


<210>  637
<211>  6638
<212>  DNA
<213>  homo sapiens

<400>  637
gcagtgagtc cacccgcccg ccgaggtccg cccgcccgcc gagacccgcc cgccgccgct       60

gccatggccg aagtgcgcaa attcaccaaa cggctcagca agcctggcac ggcggctgag      120

ctccggcaga gcgtgtctga ggccgtgcgg ggctccgtgg tgctggaaaa ggccaaagtt      180

gttgagcccc tggactatga gaatgttatt gcccaaagaa aaacccagat ttacagcgac      240

cccctccgag atctgcttat gttcccaatg gaagatatat ctatctcggt gataggtcgt      300

caacgcagaa cggtgcagtc tactgtacca gaagatgctg aaaagagggc ccagagttta      360

tttgttaaag agtgtattaa aacctatagc acagattggc acgtggtaaa ctacaagtat      420

gaggacttct ctggggactt tcgaatgttg ccatgtaaat ctttgagacc agaaaagatt      480

cctaatcatg tatttgagat agatgaagac tgtgagaaag atgaggactc atcttcttta      540

tgttctcaga agggtggtgt gataaaacaa ggctggttgc ataaagcaaa tgtaaatagt      600

accatcacag taaccatgaa ggtattcaag agacgatatt tttacttgac ccaacttcct      660

gacggttcat atattctcaa ttcctataaa gatgagaaaa attcaaaaga atcgaaaggt      720

tgcatctact tggacgcctg cattgatgtt gttcagtgcc ccaaaatgcg ccgtcatgct      780

tttgaactca agatgttaga taaatatagc cattatctgg ctgctgaaac tgagcaggaa      840

atggaggaat ggttgataac tttgaaaaag attattcaga tcaacaccga cagtttagtt      900

caagaaaaaa aggagacggt agaaacagca caagatgatg aaactagcag ccaaggaaaa      960

gccgagaaca tcatggcaag tttggaaagg agcatgcatc cggaactgat gaagtatgga     1020

agagaaactg aacaactaaa caaactcagt agaggagatg gaagacagaa tctcttttct     1080

tttgattcag aagttcagag gttggacttt tcaggaattg aacctgatat aaagccattt     1140

gaagaaaaat gcaataaacg tttcctggtg aattgccatg atttaacttt caatatcttg     1200

ggccaaattg gagacaatgc aaaaggacca cccacaaatg ttgagccctt ttttatcaat     1260

cttgccttat ttgatgtaaa gaacaattgt aagatttcag cagactttca tgtagacctg     1320

aatcccccat ctgtccgtga aatgctgtgg ggctcttcaa cccaactggc cagtgacggt     1380

agcccaaagg gctcttcacc cgaatcttac attcatggaa ttgccgaatc tcagttacgc     1440

tacatacaac agggaatttt ctcagtgacg aatccacatc ctgaaatttt tctagttgcc     1500

agaattgaaa aggtactaca gggaaacatt acacactgtg cagaacccta tatcaaaaat     1560

tctgatccag taaagacggc ccagaaggtg cacaggacag ctaaacaagt gtgtagccgc     1620

cttggacaat acagaatgcc cttcgcttgg gctgccagac ccattttcaa agatactcaa     1680

ggctctcttg atctggatgg gagattttct cctctgtata aacaagacag tagcaagctt     1740

tcaagtgaag acattctcaa gttgctctca gaatataaga agccagaaaa gaccaaactg     1800

cagattattc ctgggcagct aaacatcaca gtagaatgtg ttcctgtgga tttatcaaat     1860

tgtattactt cttcatatgt gcccttgaag ccttttgaaa agaattgcca aaatattact     1920

gtggaggttg aagagtttgt tccagaaatg acaaaatatt gttatccatt tactatttac     1980

aaaaaccatc tgtatgtata tcccctgcaa ttaaaatacg atagccagaa aacatttgcc     2040

aaggcaagga acattgcagt ctgtgtggaa ttccgggatt cagatgaaag tgacgctagt     2100

gccctaaagt gtatttatgg aaaacctgca gggtctgttt ttaccacaaa tgcttatgct     2160

gttgtctcgc atcacaacca aaatccagag ttctatgatg agattaaaat tgagcttccc     2220

attcacctac atcaaaaaca tcatttgctt ttcacttttt atcatgtaag ttgtgaaatt     2280

aacacaaagg gaacaaccaa aaagcaagac acagttgaaa ctccagttgg gtttgcctgg     2340

gtacctttgc tgaaagatgg tagaatcatc acatttgagc agcagctgcc agtttccgcc     2400

aatcttcccc caggctactt gaatctgaat gatgcagaat caagaaggca atgtaacgtg     2460

gatattaaat gggtagatgg tgcaaagcct ttgttgaaga ttaaaagcca cttagaatct     2520

accatttaca ctcaagatct gcatgtgcac aaattcttcc atcattgcca gctgattcag     2580

tcaggctcga aagaagttcc aggggagctc attaaatatt taaagtgttt gcatgccatg     2640

gagatccaag tcatgataca gtttctacct gtaattctta tgcaactctt ccgagttctc     2700

acaaatatga cccatgaaga tgacgttcct atcaactgca ccatggttct cttacatatt     2760

gtatcaaagt gccatgaaga aggcttggat agttatctaa gatcattcat aaagtatagc     2820

ttccgacctg aaaaaccgag tgctcctcag gcccagctga tacatgaaac cctggctact     2880

acgatgatag caatattgaa acagtctgca gattttttat caataaacaa attgctaaag     2940

tactcatggt ttttctttga aataattgca aagtcaatgg ccacatactt gttggaagag     3000

aataagatta agcttccccg aggccagaga tttcccgaga catatcatca tgtcttacat     3060

tcactgcttc ttgcaataat tccccatgtg actattcggt atgcggagat tcccgatgag     3120

tccagaaatg tgaactatag tttggctagc ttcctgaagc gctgtttgac actaatggat     3180

agaggattta ttttcaattt aataaatgac tatatatctg gattcagccc caaagatcct     3240

aaggttctgg ctgaatacaa gtttgaattt ctgcaaacaa tttgcaatca cgaacattac     3300

attcctctga acttgccaat ggcatttgca aaacctaaac tgcagcgggt tcaagattca     3360

aatcttgaat acagtttatc agatgagtat tgcaagcatc acttcttggt tggtctactt     3420

ctgagggaaa cttccattgc tcttcaggac aattatgaga tcagatatac agctatctct     3480

gttataaaga atcttttgat aaaacatgca tttgacacaa gataccagca caagaaccaa     3540

caagccaaaa tagcacaatt gtacctcccc tttgttggac tacttttgga aaatatacag     3600

cgattagcag gtcgagatac cttgtattct tgtgcagcca tgcctaattc tgcatccaga     3660

gatgagtttc catgtggctt tacttcacct gccaatagag ggagtctgag cactgacaaa     3720

gacaccgctt atgggtcttt tcaaaatgga catggaatta agagagaaga ttcaagaggt     3780

tccctcatcc cagaaggagc aacaggattt ccagatcagg gcaacactgg tgaaaatacc     3840

cgacagagtt ctacaaggag tagtgtatcc cagtataacc gcctggatca gtatgaaatc     3900

agaagcctcc tgatgtgcta cctgtatata gtaaaaatga tttcagaaga tactctctta     3960

acttactgga ataaagtatc acctcaggag ctcataaaca ttcttatact tttagaagta     4020

tgcttgtttc actttagata tatggggaaa agaaacatag caagggtgca tgatgcctgg     4080

ctgtcaaaac acttcggaat agaccgaaaa tcgcaaacca tgcctgctct tcgaaacaga     4140

tcaggagtaa tgcaggcccg gcttcagcat cttagtagcc tagaaagttc atttacactt     4200

aatcacagtt ctacaacaac tgaagcagac attttccacc aggcacttct tgaaggcaat     4260

acagctactg aagtttccct aacagtacta gacaccatat catttttcac tcagtgcttc     4320

aagacccaac ttttaaataa tgatggccat aacccattaa tgaaaaaagt gtttgatata     4380

catcttgctt ttcttaaaaa tggacaatct gaagtgtcgc tgaaacatgt atttgcctca     4440

ctgagagctt tcatcagtaa gtttccttca gcatttttca aaggaagagt aaacatgtgt     4500

gctgcatttt gctatgaggt tttaaagtgc tgcacatcga agattagctc aaccaggaat     4560

gaagcatctg cacttttgta tcttttgatg agaaacaact ttgagtatac caaaaggaaa     4620

acctttttga ggacacatct acagataata attgctgtaa gccaactgat agctgatgta     4680

gcactaagcg gaggatcaag atttcaggag tctttattca ttatcaataa ttttgcaaat     4740

agtgacagac ctatgaaggc aactgccttt cccgcagaag tcaaagactt gaccaagaga     4800

atccgcactg ttcttatggc cactgcccaa atgaaggagc atgagaaaga ccctgaaatg     4860

ctaattgatc tccagtatag cttagccaag tcctatgcaa gcaccccaga gctcaggaaa     4920

acctggcttg atagcatggc caagattcat gtaaaaaatg gagatttttc agaggctgcg     4980

atgtgttatg tccatgtagc agctctagtt gcagagtttc ttcatcgaaa aaaattattt     5040

cctaacggat gttcagcgtt caagaaaatt actcccaata tagatgaaga aggagcaatg     5100

aaagaagatg ctgggatgat ggatgtccat tatagtgaag aggtcttgct ggagttgcta     5160

gaacaatgtg tggatggctt atggaaggca gaacgttatg aaataatttc tgagatttcc     5220

aagttgatcg ttccaattta tgagaaacgt cgtgagtttg agaaacttac tcaagtttat     5280

agaactcttc atggagctta cacaaaaatt ctggaagtta tgcatacaaa aaagagactt     5340

ttaggcactt tcttcagagt tgccttttat ggccaatctt tttttgaaga agaagatgga     5400

aaggagtaca tctataaaga accaaagctc actggcctct cagaaatttc cttgagactt     5460

gttaaacttt atggtgaaaa gtttggtacg gagaatgtca aaataattca ggattcagac     5520

aaggtaaatg ccaaagagct tgatccaaaa tatgctcata tacaagttac ttatgtgaag     5580

ccttactttg atgacaaaga actcacagaa aggaagaccg agtttgaaag aaatcataat     5640

atcagcagat ttgtttttga ggccccttac actttatcag gcaaaaaaca gggctgtata     5700

gaagaacagt gcaaacgccg tacaatcttg acaacttcaa actcgtttcc ttacgtgaag     5760

aagaggattc ctattaactg tgaacagcag attaatttaa aaccaattga tgttgccact     5820

gatgaaataa aagataaaac tgcagagctg caaaagcttt gctcctctac tgacgtggac     5880

atgattcagc tccaacttaa attgcagggc tgtgtttctg tgcaggtcaa tgctggtcca     5940

ttagcatatg caagagcttt cttaaatgac agccaagcta gcaagtatcc acctaagaaa     6000

gtgagtgagt tgaaagacat gtttaggaaa tttatacaag catgcagcat tgcacttgaa     6060

ctaaatgagc ggctaattaa agaagatcaa gttgagtacc atgaagggct aaagtcaaat     6120

ttcagagaca tggtaaaaga attatctgac attatccatg agcagatatt acaagaagac     6180

acaatgcatt ctccctggat gagcaacaca ttacatgtat tttgtgcaat tagtggtaca     6240

tcaagtgacc gaggttatgg ttccccaaga tacgctgaag tgtgaggaaa tgcagatgta     6300

cgtgacaatg agactgacct ttctcaggaa tatttggagc tgtgcaaatg ttaaaattta     6360

aagatttgat atacatggag tgtttcttct cgacaccaaa attttcatgt gttccaacag     6420

ggtgcttaca tatttgtaaa taagcaactt gaaagtgcct ggaaaattgc accactgtgc     6480

ttggtttgta cttttttagg taaatctata tgctgaaaag tagagctcaa aaacagtagt     6540

tcaatttgct taattattgc ttaaaataat ggtactatgt aaaattgtat aatggaatac     6600

aataaaaggt aaaacttatt tgtaattaga agtgaaag                             6638


<210>  638
<211>  2953
<212>  DNA
<213>  homo sapiens

<400>  638
gagctcgccg tcgctccgtc atagagttcg ccccacccca tcccctcctt tctggactcg       60

gagctcagtt cacgcagtaa caaatgaagt gcgcgctgcg acacctccca gcccaccgaa      120

ctccgccgcc atttcctcgc ttggcctaac ggttcggcca atcccagcgc gcatcaagaa      180

ggactgaggc tccgccaatc ggaggccgcc gatttcgacc cttcgcctcg gcccggccca      240

atccaggccc cggccccgcc gcccccggcc cgcccccgcg gtgccctctc tcctccctct      300

ttgtgcgtct cgcgccgccg ccgcccgccg cgtgagagga cgggctccgc gcgctccggc      360

agcgcattcg ggtcccctcc ccccgggagg cttgcgaagg agaagccgcc gcagaggaaa      420

agcaggtgcc ggtgcctgtc cccgggggcg ccatggcgac cggagcgaac gccacgccgt      480

tggacttccc aagtaagaag cggaagagga gccgctggaa ccaagacaca atggaacaga      540

agacagtgat tccaggaatg cctacagtta ttccccctgg acttactcga gaacaagaaa      600

gagcttatat agtgcaactg cagatagaag acctgactcg taaactgcgc acaggagacc      660

tgggcatccc ccctaaccct gaggacaggt ccccttcccc tgagcccatc tacaatagcg      720

aggggaagcg gcttaacacc cgagagttcc gcacccgcaa aaagctggaa gaggagcggc      780

acaacctcat cacagagatg gttgcactca atccggattt caagccacct gcagattaca      840

aacctccagc aacacgtgtg agtgataaag tcatgattcc acaagatgag tacccagaaa      900

tcaactttgt ggggctgctc atcgggccca gagggaacac cctgaagaac atagagaagg      960

agtgcaatgc caagattatg atccggggga aagggtctgt gaaagaaggg aaggttgggc     1020

gcaaagatgg ccagatgttg ccaggagaag atgagccact tcatgccctg gttactgcca     1080

atacaatgga gaacgtcaaa aaggcagtgg aacagataag aaacatcctg aagcagggta     1140

tcgagactcc agaggaccag aatgatctac ggaagatgca gcttcgggag ttggctcgct     1200

taaatgggac ccttcgggaa gacgataaca ggatcttaag accctggcag agctcagaga     1260

cccgcagcat taccaacacc acagtgtgta ccaagtgtgg aggggctggc cacattgctt     1320

cagactgtaa attccaaagg cctggtgatc ctcagtcagc tcaggataaa gcacggatgg     1380

ataaagaata tttgtccctc atggctgaac tgggtgaagc acctgtccca gcatctgtgg     1440

gctccacctc tgggcctgcc accacacccc tggccagcgc acctcgtcct gctgctcccg     1500

ccaacaaccc acctccaccg tctctcatgt ctaccaccca gagccgccca ccctggatga     1560

attctggccc ttcagagagt cggccctacc acggcatgca tggaggtggt cctggtgggc     1620

ccggaggtgg cccccacagc ttcccacacc cattacccag cctgacaggt gggcatggtg     1680

gacatcccat gcagcacaac cccaatggac ccccaccccc ttggatgcag ccaccaccac     1740

caccgatgaa ccagggcccc caccctcctg ggcaccatgg ccctcctcca atgggtaaat     1800

cagtacctgg gaagtacgcc tgtgggctct ggggtctatc gcctgcatca aggaaaaggt     1860

atgatgccgc caccacctat gggcatgatg ccgccgccgc cgccgcctcc cagtgggcag     1920

cccccacccc ctccctctgg tcctcttccc ccatggcaac aacagcagca gcagcctccg     1980

ccaccccctc cgcccagcag cagtatggct tccagtaccc ccttgccatg gcagcaaaga     2040

tccctccccg cggcggcgat ggcccgagcc atgagagtga ggactttccg cgcccattgg     2100

tgacccttcc aggcagacag cctcagcaac gcccctggtg gacaggatgg ttcggcaaag     2160

cagcctgagt tatttttgtg gacggaatcg gaacacgctg gctccatatc gtgaaatttt     2220

tattaatttt tttctttttc ctttgttact tctttatctt ttcctttctt cagactccgt     2280

ccaaggagat gctctccccg gtcttctgct gcaatttaga ttcctttccc ttctctccag     2340

ttctccttcc cttaccaagg agaggggagc aaatggtttt gggcaagggc tttggccatt     2400

catgtcaagc tggttgtggg tttttcaagg tgccatagcc acccccaaag atgtttgttt     2460

aaagcgtggg gttttttaat ctctgccacc cttgtcaagg gagtcttgta aagttgccga     2520

gggtaggttc atctccaggt ttcgggattc ccatccgtcc tggcgatcct gccagcagtg     2580

ggtgggcagc ctgagctccc tcgggctcgc ctgccagcct ggagttcttc ctgtgctcct     2640

tgatcacctg agctgcctca gattccattt ggtcctctcc ttcctggaag gcttcctttt     2700

atgttttgtt ttaatcccaa atgtctgaat gttttgcagt gtgtaggggt ttgagcccct     2760

tgttcattct ccttcctttt tcctcccgct tccctctcca tgaagtgatt ctgttgacaa     2820

taatgtatac tgcgcgttct cttcactggt ttatctgcag aaatttctct gggctttttt     2880

cggtgttaga ttcaacactg cgctaaagcg gggatgttcc attgaataaa agagcagtgt     2940

ggttttctgg gtc                                                        2953


<210>  639
<211>  3791
<212>  DNA
<213>  homo sapiens

<400>  639
aagagggggc ggggcggaag cggcggcggc gcgcgcaaag ctgcagcgtc tggaaaaaag       60

cgacttgtgg cggtcgagcg tggcgcaggc gaatcctcgg cactaagcaa atatggacct      120

cgcggcggca gcggagccgg gcgccggcag ccagcacctg gaggtccgcg acgaggtggc      180

cgagaagtgc cagaaactgt tcctggactt cttggaggag tttcagagca gcgatggaga      240

aattaaatac ttgcaattag cagaggaact gattcgtcct gagagaaaca cattggttgt      300

gagttttgtg gacctggaac aatttaacca gcaactttcc accaccattc aagaggagtt      360

ctatagagtt tacccttacc tgtgtcgggc cttgaaaaca ttcgtcaaag accgtaaaga      420

gatccctctt gccaaggatt tttatgttgc attccaagac ctgcctacca gacacaagat      480

tcgagagctc acctcatcca gaattggttt gctcactcgc atcagtgggc aggtggtgcg      540

gactcaccca gttcacccag agcttgtgag cggaactttt ctgtgcttgg actgtcagac      600

agtgatcagg gatgtagaac agcagttcaa atacacacag ccaaacatct gccgaaatcc      660

agtttgtgcc aacaggagga gattcttact ggatacaaat aaatcaagat ttgttgattt      720

tcaaaaggtt cgtattcaag agacccaagc tgagcttcct cgagggagta tcccccgcag      780

tttagaagta attttaaggg ctgaagctgt ggaatcagct caagctggtg acaagtgtga      840

ctttacaggg acactgattg ttgtgcctga cgtctccaag cttagcacac caggagcacg      900

tgcagaaact aattcccgtg tcagtggtgt tgatggatat gagacagaag gcattcgagg      960

actccgggcc cttggtgtta gggacctttc ttataggctg gtctttcttg cctgctgtgt     1020

tgcgccaacc aacccaaggt ttggggggaa agagctcaga gatgaggaac agacagctga     1080

gagcattaag aaccaaatga ctgtgaaaga atgggagaaa gtgtttgaga tgagtcaaga     1140

taaaaatcta taccacaatc tttgtaccag cctgttccct actatacatg gcaatgatga     1200

agtaaaacgg ggtgtcctgc tgatgctctt tggtggcgtt ccaaagacaa caggagaagg     1260

gacctctctt cgaggggaca taaatgtttg cattgttggt gacccaagta cagctaagag     1320

ccaatttctc aagcacgtgg aggagttcag ccccagagct gtctacacca gtggtaaagc     1380

gtccagtgct gctggcttaa cagcagctgt tgtgagagat gaagaatctc atgagtttgt     1440

cattgaggct ggagctttga tgttggctga taatggtgtg tgttgtattg atgaatttga     1500

taagatggac gtgcgggatc aagttgctat tcatgaagct atggaacagc agaccatatc     1560

catcactaaa gcaggagtga aggctactct gaacgcccgg acgtccattt tggcagcagc     1620

aaacccaatc agtggacact atgacagatc aaaatcattg aaacagaata taaatttgtc     1680

agctcccatc atgtcccgat tcgatctctt ctttatcctt gtggatgaat gtaatgaggt     1740

tacagattat gccattgcca ggcgcatagt agatttgcat tcaagaattg aggaatcaat     1800

tgatcgtgtc tattccctcg atgatatcag aagatatctt ctctttgcaa gacagtttaa     1860

acccaagatt tccaaagagt cagaggactt cattgtggag caatataaac atctccgcca     1920

gagagatggt tctggagtga ccaagtcttc atggaggatt acagtgcgac agcttgagag     1980

catgattcgt ctctctgaag ctatggctcg gatgcactgc tgtgatgagg tccaacctaa     2040

acatgtgaag gaagctttcc ggttactgaa taaatcaatc atccgtgtgg aaacacctga     2100

tgtcaatcta gatcaagagg aagagatcca gatggaggta gatgagggtg ctggtggcat     2160

caatggtcat gctgacagcc ctgctcctgt gaacgggatc aatggctaca atgaagacat     2220

aaatcaagag tctgctccca aagcctcctt aaggctgggc ttctctgagt actgccgaat     2280

ctctaacctt attgtgcttc acctcagaaa ggtggaagaa gaagaggacg agtcagcatt     2340

aaagaggagc gagcttgtta actggtactt gaaggaaatc gaatcagaga tagactctga     2400

agaagaactt ataaataaaa aaagaatcat agagaaagtt attcatcgac tcacacacta     2460

tgatcatgtt ctaattgagc tcacccaggc tggattgaaa ggctccacag agggaagtga     2520

gagctatgaa gaagatccct acttggtagt taaccctaac tacttgctcg aagattgaga     2580

tagtgaaagt aactgaccag agctgaggaa ctgtggcaca gcacctcgtg gcctggagcc     2640

tggctggagc tctgctaggg acagaagtgt ttctggaagt gatgcttcca ggatttgttt     2700

tcagaaacaa gaattgagtt gatggtccta tgtgtcacat tcatcacagg tttcatacca     2760

acacaggctt cagcacttcc tttggtgtgt ttcctgtccc agtgaagttg gaaccaaata     2820

atgtgtagtc tctataacca atacctttgt tttcatgtgt aagaaaaggc ccattacttt     2880

taaggtatgt gctgtcctat tgagcaaata actttttttc aattgccagc tactgctttt     2940

attcatcaaa ataaaataac ttgttctgaa gttgtctatt ggatttcttt ctactgtacc     3000

ctgattatta cttccatcta cttctgaatg tgagactttc cctttttgct taacctggag     3060

tgaagaggta gaactgtggt attatggatg aggtttctat gagaaggagt cattagagaa     3120

ctcatatgaa agctagaggc cttagagatg actttccaag gttaattcca gttgtttttt     3180

ttttttttta agtttataaa agtttattat acttttttaa aattactctt tagtaattta     3240

ttttacttct gtgtcctaag ggtaatttct caggattgtt ttcaaattgc ttttttaggg     3300

gaaataggtc atttgctata ttacaagcaa tccccaaatt ttatggtctt ccaggaaaag     3360

ttattaccgt ttatgatact aacagttcct gagacttagc tatgatcagt atgttcatga     3420

ggtggagcag ttcctgtgtt gcagctttta acaacagatg gcattcatta aatcacaaag     3480

tatgttaaag gtcacaaaag caaaataact gtctgaggct aaggcccacg tgggacagtc     3540

taatacccat gagtactcaa cttgccttga tgtctgagct ttccagtgca atgtgaattt     3600

gagcagccag aaatctatta gtagaaagca agacagatta atataggtta aaacaatgat     3660

ttaaatatgt ttctcccaat aattatctct ttccctggaa tcaacttgta tgaaaccttg     3720

tcaaaatgta ctccacaagt atgtacaatt aagtatttta aaaataaatg gcaaacatta     3780

aaaacaaaaa a                                                          3791


<210>  640
<211>  6067
<212>  DNA
<213>  homo sapiens

<400>  640
aaaggggggg aacctagagt cggtgggggg gaagcgatgt ttgcccgtca gtcgagtccg       60

gagtgaggag ctcggtcgcc gaagcggagg gagactcttg agcttcatct tgccgccgcc      120

acggccaccg cctggacctt tgcccggagg gagctgcaga gggtccatcg ccgccgtcct      180

ctggagggca gcgcgattgg gggcccggac ctccagtccg ggggggattt ttcgtcgtcc      240

ccctcccccc aaccagggag cccgagcggc cgccaaacaa aggtaccagt cgccgccgcg      300

ggaggaggag gagccggagc ctctgcctca gcagccgctg gacccgccgc ccttcttccc      360

catctctccc ccgggcctgc tggttttggg ggggagaagg agagagggga ctctggacgt      420

gccagggtca gatctcgcct ccgaggaagg tgcagctgaa cctggtgttt tagaggatac      480

cttggtccca gagtcatcat gaaggccctt gatgagcctc cctatttgac agtgggcact      540

gatgtgagtg ctaaatacag aggagccttt tgtgaagcca agatcaagac agcaaaaaga      600

cttgtcaaag tcaaggtgac atttagacat gattcttcaa cagtggaagt tcaggatgac      660

cacataaagg gcccactaaa ggtaggagct attgtggaag tgaagaatct tgatggtgca      720

tatcaggaag ctgttatcaa taaactaaca gatgcgagtt ggtacactgt agtttttgat      780

gacggagatg agaagacact gagacgatct tcactgtgcc tgaaaggaga gaggcatttt      840

gctgaaagtg aaacattaga ccagctccca ctcaccaacc ctgagcattt tggcactcca      900

gtcataggaa agaaaacaaa tagaggaaga agatctaatc atataccaga ggaagagtct      960

tcatcatcct ccagtgatga agatgaggat gataggaaac agattgatga gctactaggc     1020

aaagttgtat gtgtagatta cattagtttg gataaaaaga aagcactgtg gtttcctgca     1080

ttggtggttt gtcctgattg tagtgatgag attgctgtaa aaaaggacaa tattcttgtt     1140

cgatctttca aagatggaaa atttacttca gttccaagaa aagatgtcca tgaaattact     1200

agtgacactg caccaaagcc tgatgctgtt ttaaagcaag cctttgaaca ggcacttgaa     1260

tttcacaaaa gtagaactat tcctgctaac tggaagactg aattgaaaga agatagctct     1320

agcagtgaag cagaggaaga agaggaggag gaagatgatg aaaaagaaaa ggaggataat     1380

agcagtgaag aagaagaaga aatagaacca tttccagaag aaagggagaa ctttcttcag     1440

caattgtaca aatttatgga agatagaggt acacctatta acaaacgacc tgtacttgga     1500

tatcgaaatt tgaatctctt taagttattc agacttgtac acaaacttgg aggatttgat     1560

aatattgaaa gtggagctgt ttggaaacaa gtctaccaag atcttggaat ccctgtctta     1620

aattcagctg caggatacaa tgttaaatgt gcttataaaa aatacttata tggttttgag     1680

gagtactgta gatcagccaa cattgaattt cagatggcat tgccagagaa agttgttaac     1740

aagcaatgta aggagtgtga aaatgtaaaa gaaataaaag ttaaggagga aaatgaaaca     1800

gagatcaaag aaataaagat ggaggaggag aggaatataa taccaagaga agaaaagcct     1860

attgaggatg aaattgaaag aaaagaaaat attaagccct ctctgggaag taaaaagaat     1920

ttattagaat ctatacctac acattctgat caggaaaaag aagttaacat taaaaaacca     1980

gaagacaatg aaaatctgga tgacaaagat gatgacacaa ctagggtaga tgaatccctc     2040

aacataaagg tagaagctga ggaagaaaaa gcaaaatctg gagatgaaac gaataaagaa     2100

gaagatgaag atgatgaaga agcagaagag gaggaggagg aggaagaaga agaagaggat     2160

gaagatgatg atgacaacaa tgaggaagag gagtttgagt gctatccacc aggcatgaaa     2220

gtccaagtgc ggtatggacg agggaaaaat caaaaaatgt atgaagctag tattaaagat     2280

tctgatgtcg aaggtggaga ggtcctttac ttggtgcatt actgcggatg gaatgtgaga     2340

tacgatgaat ggattaaagc agataaaata gtaagacctg ctgataaaaa tgtgccaaag     2400

ataaaacatc ggaagaaaat aaagaataaa ttagacaaag aaaaagacaa agatgaaaaa     2460

tactctccaa aaaactgtaa acttcggcgc ttgtccaaac caccatttca gacaaatcca     2520

tctcctgaaa tggtatccaa actggatctc actgatgcca aaaactctga tactgctcat     2580

attaagtcca tagaaattac ttcgatcctt aatggacttc aagcttctga aagttctgct     2640

gaagacagtg agcaggaaga tgagagaggt gctcaagaca tggataataa tggcaaagag     2700

gaatctaaga ttgatcattt gaccaacaac agaaatgatc ttatttcaaa ggaggaacag     2760

aacagttcat ctttgctaga agaaaacaaa gttcatgcag atttggtaat atccaaacca     2820

gtgtcaaaat ctccagaaag attaaggaaa gatatagaag tattatccga agatactgat     2880

tatgaagaag atgaagtcac aaaaaagaga aaggatgtca agaaggacac aacagataaa     2940

tcttcaaaac cacaaataaa acgtggtaaa agaaggtatt gcaatacaga agagtgtcta     3000

aaaactggat cacctggcaa aaaggaagag aaggccaaga acaaagaatc actttgcatg     3060

gaaaacagta gcaacagctc ttcagatgaa gatgaagaag aaacaaaagc aaagatgaca     3120

ccaactaaga aatacaatgg tttggaggaa aaaagaaaat ctctacggac aactggtttc     3180

tattcaggat tttcagaagt ggcagaaaaa aggattaaac ttttaaataa ctctgatgaa     3240

agacttcaaa acagcagggc caaagatcga aaagatgtct ggtcaagtat tcagggacag     3300

tggcctaaaa aaacgctgaa agagcttttt tcagactctg atactgaggc tgcagcttcc     3360

ccaccgcatc ctgccccaga ggagggggtg gcagaggagt cactgcagac tgtggctgaa     3420

gaggagagtt gttcacccag tgtagaacta gaaaaaccac ctccagtcaa tgtcgatagt     3480

aaacccattg aagaaaaaac agtagaggtc aatgacagaa aagcagaatt tccaagtagt     3540

ggcagtaatt cagtgctaaa tacccctcct actacacctg aatcgccttc atcagtcact     3600

gtaacagaag gcagccggca gcagtcttct gtaacagtat cagaaccact ggctccaaac     3660

caagaagagg ttcgaagtat caagagtgaa actgatagca caattgaggt ggatagtgtt     3720

gctggggagc tccaagacct ccagtctgaa gggaatagct cgccagcagg ttttgatgcc     3780

agtgtgagct caagcagtag taatcagcca gaaccagaac atcctgaaaa agcctgtaca     3840

ggtcagaaaa gagtgaaaga tgctcaggga ggaggaagtt catcaaaaaa gcagaaaaga     3900

agccataaag caacagtggt aaacaacaaa aagaagggaa aaggcacaaa tagtagtgat     3960

agtgaagaac tttcagctgg tgaaagtata actaagagtc agccagtcaa atcagtttcc     4020

actggaatga agtctcatag taccaaatct cccgcaagga cgcagtctcc aggaaaatgt     4080

ggaaagaatg gtgataagga tcctgatctc aaggaaccca gtaatcgatt acccaaagtt     4140

tacaaatgga gttttcagat gtcggacctg gaaaatatga caagtgccga acgcatcaca     4200

attcttcaag aaaaacttca agaaatcaga aaacattatc tgtcattaaa atctgaagta     4260

gcttccattg atcggaggag aaagcgttta aagaagaaag agagagaaag tgctgctaca     4320

tcctcatcct cctcttcacc ttcatccagt tccataacag ctgctgttat gttaacttta     4380

gctgaaccgt caatgtccag cgcatcacaa aatggaatgt cagttgagtg caggtgacag     4440

caggacttgc taaagcactt tgcacttaat ggctgttgag ggccactttt tttttatact     4500

gcacagtggc acaaaaaaat atcagacaag cactatttta tatttaaaaa ttgtttcttg     4560

acaagctgac ttggcactta agtgcacttt tttatgaaga aaaagtacaa tgaactgctt     4620

ttcctcaagc aataattgtt tccaacttgt ctgggaattg tgtgtctggt aactggaagg     4680

ccttccactg tggcaaatgg aggcttttca ctgcctgtag agacaataca gtaagcatag     4740

ttaaggggtg ggtcagaaca tgttaagata acttactgta tatgtattcc cttgtatttt     4800

gttaaagctg gaacatttga tatttttcca tttatttatg aaaaaatatg aacctatttt     4860

catttgtaca aggtaattgt tttttaaagc aagtcacctt agggtggctt taattgtata     4920

agtcaagcac atgtaataaa ttcaaaacct gcagttaaca ggatattaga catcaatcct     4980

ggtaaccaaa tattaaagat tctctttaaa aaagactgaa catgtttaca ggtttgaatt     5040

aggctaaaag gtcttgcagt ggcttttcat ggcccttcaa attggaatgg aactactgta     5100

ctttgccatt tttctataaa tcagtatttt tttttaattt tgatatacat tgtgtgaaaa     5160

aagaaaatgg ctaataaact gtattaaatc ttaaacaatg tataaagatt gtacttagcc     5220

agttcaaagt gtatatttat tcataatgaa ttataacagt tatatttttg tgttttcttg     5280

taaatgtttc ttttccctta aatacagata attcatttgt attgcttatt ttattatgag     5340

ctacaacaaa aggacttcag gaacaagtaa tgtattagta tggttcaaga ttgttgatag     5400

gaactgtctc aaaaggatgg tggttatttt aaatataaat agctaatggg ggtggtaggc     5460

ctataaaatt aaatgccttg tataaaatcc aaaatgaatg caaaattgtt ttcacttgta     5520

ttgactttat gttgtatgat tccaatctct gttctgtttg gcacttgtat ttaattcttc     5580

acctttgtaa gacatttgta tattgtggat gtgttcattc aagctattta atatctggca     5640

ctgttaatac acagtacttt attgtacaga ctgttttact gttttaattg tagttctgtg     5700

tacttttttt ggatggggct ggcatgtttt ctttgtttcc tggcaatacg acgtgggaat     5760

ttcaatgcgt tttgttgtag atgctaacgt gtcagaatcc tttacattca acttttctaa     5820

gaaaagcatt ttcagtcttg tagtgtgtgc ttacagtaac taattttgtt gaaaatggtt     5880

tcaagttatt caaatttgta caggactgta aagatttgtt gacagcaaaa tgttgaagaa     5940

aaaagcttat agaataaaag ctataaagta tatattagga tctgcaaaca atgaagaatt     6000

atgtaatata ttgtacaaat gtaagcaaag gctctgaaat aaaatgccat agtttgtgaa     6060

tccttga                                                               6067


<210>  641
<211>  2175
<212>  DNA
<213>  homo sapiens

<400>  641
ggggaggcgc ggcgcgccgg ggacagcggc ggacggcggc ggcggcggca tgcggctcct       60

cgcgctgccc atcgtgggct gaggcggccg cagaaccggc gggaggcgcg gcggccgggc      120

gagccgaggg cgcagccagc cgggcggacc gcggacagcg gtcggggcgc cgcgccatgg      180

ggcgagccgg gggcgggggc ccgggccggg ggccgccgcc actgctgctg tttctggggg      240

ccgcgctggt cctggcctct ggggccgtgc cggcgcgtga ggcgggcagc gcggttgagg      300

ccgaagagct ggtgaagggc agcccggcgt gggagccgcc tgccaacgac acgcgggaag      360

aagccggccc accagcggct ggggaagatg aggcgtcgtg gacggcgccc ggtggcgagc      420

tggccgggcc agaagaggtg ctgcaggagt cggctgcggt gaccggcacc gcctggctgg      480

aagctgacag cccaggcctg ggaggagtga ccgcagaggc gggcagcggc gatgcccagg      540

cccttccagc tacgctccag gctccccacg aggtcctcgg gcagtcaatc atgccccctg      600

ccattcctga ggctacagag gccagcgggc caccctcccc cacccccggc gacaagctga      660

gcccagcttc tgaactcccc aaggagagcc ccttggaggt ttggctgaac ctggggggca      720

gcacacccga ccctcaaggg ccagagctga cttacccatt tcagggcacc ctggagcccc      780

aaccggcatc agatatcatt gacatcgact acttcgaagg actggatggt gagggtcgtg      840

gcgcagatct ggggagcttc ccagggtcac caggaacctc agagaaccac cctgatactg      900

agggagagac cccttcctgg agcctgcttg acttatacga tgatttcacc cccttcgatg      960

aatctgattt ctaccccacc acatcctttt atgatgactt ggatgaagag gaggaggaag     1020

aggaggatga caaagatgca gtaggaggtg gagacctaga agatgaaaat gagcttctag     1080

tgcccactgg gaagcctggt ctggggcccg ggacaggcca gcccaccagt cggtggcatg     1140

ctgtccctcc acagcacact ctggggtcgg tccccggcag cagcatcgcc ctcaggcccc     1200

gcccaggaga gccaggcagg gacttggcct ccagtgaaaa tggcactgag tgccgcagtg     1260

gctttgtgcg gcataacggc tcctgccggt cagtgtgcga cctcttccca agttactgtc     1320

acaatggcgg ccagtgctac ctggtggaga acataggggc cttctgcagg tgcaacacgc     1380

aggactacat ctggcacaag gggatgcgct gcgagtccat catcaccgac ttccaggtga     1440

tgtgcgtggc cgtgggctcg gctgccctcg tcctgctcct gctcttcatg atgacggtgt     1500

tctttgccaa gaagctctac ctgctcaaga cggagaatac caagctgcgt aggaccaaca     1560

aattccggac cccatctgag ctccacaatg ataacttctc cctctccacc attgccgagg     1620

gctctcaccc aaatgatgat cctagtgctc cccacaaaat ccaggaggtt ctcaagtcct     1680

gcctgaaaga ggaggagtca tttaacatcc agaactccat gtcgcccaaa cttgagggtg     1740

gcaaaggtga ccaggctgac ttggatgtga actgtcttca gaataattta acctaaagca     1800

gagcaagaag agaggaagcg ggggtagtgg gtggggggta ggggaagaaa cattatctcc     1860

tcttgtacag agtctatttc ttgtaaccat ttgttaaact cttttctttt tctgatctca     1920

tggcatgctt ttatgtattt tgtacaggag gcaaaaaaat acttaaaata agcaaagaaa     1980

ctgaacagaa ttgcatacat tgggttgttt tttctgtgct gtctgtacat tgcttctgct     2040

gctgtgattt ctaaacctgt gctgttattc aactgacttt tttttgtact ttgacccacg     2100

tttttttgaa ataccagtaa aaaacaaagt tcttgaaata aaacttttta aaaagttaaa     2160

aaaaaaaaaa aaaaa                                                      2175


<210>  642
<211>  3452
<212>  DNA
<213>  homo sapiens

<400>  642
aaaatcgcgc gcggccccgc ggccagcctg ggtaggggca aggcgcagcc aatgggaagg       60

gtcggaggca tggcacagcc aatgggaagg gccggggcac caaagccaat gggaagggcc      120

gggagcgcgc ggcgcgggag atttaaaggc tgctggagtg aggggtcgcc cgtgcaccct      180

gtcccagccg tcctgtcctg gctgctcgct ctgcttcgct gcgcctccac tatgctctcc      240

ctccgtgtcc cgctcgcgcc catcacggac ccgcagcagc tgcagctctc gccgctgaag      300

gggctcagct tggtcgacaa ggagaacacg ccgccggccc tgagcgggac ccgcgtcctg      360

gccagcaaga ccgcgaggag gatcttccag gagcccacgg agccgaaaac taaagcagct      420

gcccccggcg tggaggatga gccgctgctg agagaaaacc cccgccgctt tgtcatcttc      480

cccatcgagt accatgatat ctggcagatg tataagaagg cagaggcttc cttttggacc      540

gccgaggagg tggacctctc caaggacatt cagcactggg aatccctgaa acccgaggag      600

agatatttta tatcccatgt tctggctttc tttgcagcaa gcgatggcat agtaaatgaa      660

aacttggtgg agcgatttag ccaagaagtt cagattacag aagcccgctg tttctatggc      720

ttccaaattg ccatggaaaa catacattct gaaatgtata gtcttcttat tgacacttac      780

ataaaagatc ccaaagaaag ggaatttctc ttcaatgcca ttgaaacgat gccttgtgtc      840

aagaagaagg cagactgggc cttgcgctgg attggggaca aagaggctac ctatggtgaa      900

cgtgttgtag cctttgctgc agtggaaggc attttctttt ccggttcttt tgcgtcgata      960

ttctggctca agaaacgagg actgatgcct ggcctcacat tttctaatga acttattagc     1020

agagatgagg gtttacactg tgattttgct tgcctgatgt tcaaacacct ggtacacaaa     1080

ccatcggagg agagagtaag agaaataatt atcaatgctg ttcggataga acaggagttc     1140

ctcactgagg ccttgcctgt gaagctcatt gggatgaatt gcactctaat gaagcaatac     1200

attgagtttg tggcagacag acttatgctg gaactgggtt ttagcaaggt tttcagagta     1260

gagaacccat ttgactttat ggagaatatt tcactggaag gaaagactaa cttctttgag     1320

aagagagtag gcgagtatca gaggatggga gtgatgtcaa gtccaacaga gaattctttt     1380

accttggatg ctgacttcta aatgaactga agatgtgccc ttacttggct gatttttttt     1440

ttccatctca taagaaaaat cagctgaagt gttaccaact agccacacca tgaattgtcc     1500

gtaatgttca ttaacagcat ctttaaaact gtgtagctac ctcacaacca gtcctgtctg     1560

tttatagtgc tggtagtatc accttttgcc agaaggcctg gctggctgtg acttaccata     1620

gcagtgacaa tggcagtctt ggctttaaag tgaggggtga ccctttagtg agcttagcac     1680

agcgggatta aacagtcctt taaccagcac agccagttaa aagatgcagc ctcactgctt     1740

caacgcagat tttaatgttt acttaaatat aaacctggca ctttacaaac aaataaacat     1800

tgtttgtact cacaaggcga taatagcttg atttatttgg tttctacacc aaatacattc     1860

tcctgaccac taatgggagc caattcacaa ttcactaagt gactaaagta agttaaactt     1920

gtgtagacta agcatgtaat ttttaagttt tattttaatg aattaaaata tttgttaacc     1980

aactttaaag tcagtcctgt gtatacctag atattagtca gttggtgcca gatagaagac     2040

aggttgtgtt tttatcctgt ggcttgtgta gtgtcctggg attctctgcc ccctctgagt     2100

agagtgttgt gggataaagg aatctctcag ggcaaggagc ttcttaagtt aaatcactag     2160

aaatttaggg gtgatctggg ccttcatatg tgtgagaagc cgtttcattt tatttctcac     2220

tgtattttcc tcaacgtctg gttgatgaga aaaaattctt gaagagtttt catatgtggg     2280

agctaaggta gtattgtaaa atttcaagtc atccttaaac aaaatgatcc acctaagatc     2340

ttgcccctgt taagtggtga aatcaactag aggtggttcc tacaagttgt tcattctagt     2400

tttgtttggt gtaagtaggt tgtgtgagtt aattcattta tatttactat gtctgttaaa     2460

tcagaaattt tttattatct atgttcttct agattttacc tgtagttcat acttcagtca     2520

cccagtgtct tattctggca ttgtctaaat ctgagcattg tctaggggga tcttaaactt     2580

tagtaggaaa ccatgagctg ttaatacagt ttccattcaa atattaattt cagaatgaaa     2640

cataattttt tttttttttt ttgagatgga gtctcgctct gttgcccagg ctggagtgca     2700

gtggcgcgat tttggctcac tgtaacctcc atctcctggg ttcaagcaat tctcctgtct     2760

cagcctccct agtagctggg actgcaggta tgtgctacca cacctggcta atttttgtat     2820

ttttagtaga gatggagttt caccatattg gtcaggctgg tcttgaactc ctgacctcag     2880

gtgatccacc cacctcggcc tcccaaagtg ctgggattgc aggcgtgata aacaaatatt     2940

cttaataggg ctactttgaa ttaatctgcc tttatgtttg ggagaagaaa gctgagacat     3000

tgcatgaaag atgatgagag ataaatgttg atcttttggc cccatttgtt aattgtattc     3060

agtatttgaa cgtcgtcctg tttattgtta gttttcttca tcatttattg tatagacaat     3120

ttttaaatct ctgtaatatg atacattttc ctatctttta agttattgtt acctaaagtt     3180

aatccagatt atatggtcct tatatgtgta caacattaaa atgaaaggct ttgtcttgca     3240

ttgtgaggta caggcggaag ttggaatcag gttttaggat tctgtctctc attagctgaa     3300

taatgtgagg attaacttct gccagctcag accatttcct aatcagttga aagggaaaca     3360

agtatttcag tctcaaaatt gaataatgca caagtcttaa gtgattaaaa taaaactgtt     3420

cttatgtcag tttcaaaaaa aaaaaaaaaa aa                                   3452


<210>  643
<211>  8659
<212>  DNA
<213>  homo sapiens

<400>  643
atatgacttg cccatttgtg aatttggctc cccaactcct cgcttcactt cacctgtgcc       60

tccctggtcc gcgcacttcg caggcgcccg cccgcctctc ggccacctct gcagcctgcc      120

aggcacctcc tcttgcgctc tcgctgattt cgcccaccca cctccctcca ccccgtgcca      180

cgttggtttg ggtggctgct ccgcaccggg ttcctcctcc tctcctcttt ccctccagtc      240

cttcttattc tcttcctctg gctgcggtgg ctgctgctgc tgctggtttt catccagttg      300

ggaaacccag gaagccggcg gctgctccgt ggcgctagtc cagcacgccc agggttaaaa      360

gcctcgcgcc cttccgcgga gactcccagg aacacccgaa gaactcttcc acctgcagcc      420

cccttttgcc tggcagttct gcattgcatc tcatggaagt ggaaacagga aaataaaaat      480

gttcaaactc cttggatgtt gggataaact cacctgaacc cacttgggtt cgggctgcct      540

ccttctcttc cttcattgcc acctttcctc tgtgtggctc ccgggagtgt gcggttaagt      600

catcagactc gaagtgccta gagatccgga ggaagccgcg ccggtcttcc cctgacatgc      660

gtggcatgcc ggggctccgt aggaggtttg ctatacctgg gaggaccctg gcattctaaa      720

tttcagctcc gggaaagaga aggggctttt tgccttttat cttttttttt tctttcttta      780

agtagtaatt ttttaactga ttcattgttt ggaaagcgca tattgcttcc ctcttccccg      840

aattctggca actcttcctc ctgctatgat gggcccttgg gcatcatgaa cttcattact      900

cctcactggc tggaattcaa actgcccatc tgtagtggtc ccgtgcgttg accatgcacc      960

tgagaatcca cgcgagacgg agccctcctc gccggccggc ctggacgctt gggatctggt     1020

tcctgttctg gggatgtatc gtcagctctg tatggagttc ttctaatgta gcttcctcct     1080

cctccacctc ttcctcgccg gggtctcact ctcagcacga gcaccatttc catggcagca     1140

agcatcactc agtgcctatt tctatctatc gttcccctgt ttcccttcga ggaggacacg     1200

ctggcgctac gtacatcttt gggaaaagtg gtgggcttat cctctacacc tggccagcca     1260

atgacaggcc cagcacgcgg tctgaccgcc ttgccgtggg cttcagcacc actgtgaagg     1320

atggcatctt ggtccgcatc gacagtgctc caggacttgg tgacttcctc cagcttcaca     1380

tagaacaggg gaaaattgga gttgtcttca acattggcac agttgacatc tccatcaaag     1440

aggagagaac ccctgtaaat gacggcaaat accatgtggt acgcttcacc aggaacggcg     1500

gcaacgccac cctgcaggtg gacaactggc cagtgaatga acattatcct acaggcaaca     1560

ctgataatga acgcttccaa atggtaaaac agaaaatccc cttcaaatat aatcggcctg     1620

tagaggagtg gctgcaggaa aaaggccggc agttaaccat cttcaacact caggcgcaaa     1680

tagccattgg tggaaaggac aaaggacgcc tcttccaagg ccaactctct gggctctatt     1740

atgatggttt gaaagtactg aacatggcgg ctgagaacaa ccccaatatt aaaatcaatg     1800

gaagtgttcg gctggttgga gaagtcccat caattttggg aacaacacag acgacctcca     1860

tgccaccaga aatgtctact actgtcatgg aaaccactac tacaatggcg actaccacaa     1920

cccgtaagaa tcgctctaca gccagcattc agccaacatc agatgatctt gtttcatctg     1980

ctgaatgttc aagtgatgat gaagactttg ttgaatgtga gccgagtaca gcaaacccca     2040

cggagccggg aatcagacgg gttccggggg cctcagaggt gatccgggag tcgagcagca     2100

caacagggat ggtcgtcggc attgtggctg ctgccgccct ctgcatcttg atcctcctgt     2160

acgccatgta caagtacagg aacagggacg aggggtccta tcaagtggac gagacgcgga     2220

actacatcag caactccgcc cagagcaacg gcacgctcat gaaggagaag cagcagagct     2280

cgaagagcgg ccacaagaaa cagaaaaaca aggacaggga gtattacgtg taaacatgcg     2340

aacactgctc acacgcgagt tttcacagtt atttctatcc acgcctatga atctttggac     2400

ggtgagatct cacagatgtc agaactgctg gaactatgaa atggggtata taaccacgac     2460

tctggtgggg aaaaccgttt tttaaaggac acacacacac acagcgatgc atctctctct     2520

aaagctcagc cacggctgcg gcaaggtccc agcggtcgct gggagacaga aggttttgtg     2580

ccctgctgta tcataaagca cacacttagc gctctggagc cggacggtgg ctccaccact     2640

tccgcaggcc tggaaacttc cttctccgga ggacctttta ctaaaaggta gaagacttca     2700

tggcttactt gttccataac tccaagtgag tctgtaatgt ttgtgaagct tgactgtaac     2760

catgtttttt ctgtttaatt atgtaaaaaa caaaactaca acaacaaaaa aagaaaaaag     2820

ttaaaaaaga aaaaaacacc aaaaaacaaa aacaaacaaa aaaaaaaacc cacaaccctt     2880

atctggttct gaccagtgtg cgtgtaactt tatgatctga ggggaaaaat ggcttttggg     2940

tttttgttta tttttttgat aatgactgga catcagaaga ggaaaaaaac tcaaaacaaa     3000

agcgagagag actattgcca tatgaactca aaagctatca tggtgttcac tctacatatc     3060

aggttatggt gtctctagaa tctgttgttt gtttcctata agatgctttg ctgaacacat     3120

agcaaaattc atgtgacgga tgataaattg attcgaaaag ctggtccccc aggatctaat     3180

ttcagaattt accacccaaa cccggaacag atgggtttag ggctggtgtt atcagagcta     3240

ttggctttac gtaacaatat tgttcctgtc cattcaccca gccaaattgt gttaaagagg     3300

aaagccccac aaactaaaac agcctttcct agggaagagg aaggggaggt gggctggatc     3360

tgtgactgat tgaaatgcat gcaaataaaa aagacaatat taaagtctgt tatcaaacca     3420

gacagtaggg gagttcaact cgtgatggaa ccacaaaagg tcacacaagc caaccatgtc     3480

atgccagagt acaaaacaca tagttctttc cccgccccga atgtgacaat ggttttcata     3540

gtggtttaat tttgtagcct gacatttatg gataactctg tccttccatt tgctcacttc     3600

tctcttcacc catctttttt aaaaacaaat aaatgaataa agctgctgtg acacacacac     3660

aaaaggaatt taatagtata atatatatat aaataaatat atatacagat atatttatca     3720

tggtatgttt gatgggatga ctgacacagg aaatctgtta aagtcttaaa atggaatgag     3780

aatgttgttt taaaagaaaa tagcaaaaca acaaaaaagc aaaccttaaa atgtgaagaa     3840

agtgtgaatt ttagttttgt cacagttaac tgtgtcaaag agaattaaaa aaaaaaactt     3900

cagattttgt ttacatattt tactacattt ttgctggtat aattccttag ccacctatgt     3960

acatactgct ttaagaaatg tttttttcct gtttatttct gtttggttta tattctggtt     4020

gtctttttct ttttgtaaag aggaaacaat gtacagaaaa acaataaact ggttgtatgg     4080

ccatagctat ccgaaaagca agagacaaag caagacaaat attcacacaa aaatgaagtg     4140

tgtcctctgg agggtcagat atacaatttc ttttgtacag atgaaaatca atcagctgct     4200

tagatttaga aatctactct tgctggtctt tgtaagttgc atgaatattt gactttgaaa     4260

aaatatctta acgacatggg gcaaaaagtg caatctaaat ggtagccttt actaatgtgt     4320

gtggaaagag gtgttcctca ttatctaata tttcaatgtg ttaagagttt aatttttttg     4380

ttatcattaa aaaagacagg attataaaga gatatcaaag cacgatttta gataacctaa     4440

acggcccagc ctatacgaag ttgattatat ctcgatgtct gtaaaagatt gctgttcttg     4500

gagtcttgag gtcttgtgaa ttgatttcct gctttctttc atttttttca atttaagtaa     4560

taatacattt gttatattcc tttcagtgta agtttctatt tggacaattt tatgggaaca     4620

tgtgcattct ctatgtgagc ttctatcata ttcctgtttt attagcagaa cctaaaggaa     4680

tttatttaat gatgttgtga cattactgct ttttcttttt tcttttctta gttcatattt     4740

gcattttcgt tcaaggatat gcttagcaat aaaatgttct tcccaaaacc ttgtatgctg     4800

atgcactttt attttcttaa catttgagaa aatctcgcac tgaagctaat tatgtcatat     4860

cttattaaaa gccgagtaag agctagacca ctttcatgtg atagaagata ttctaagcag     4920

ttactaatta ttacattatc aaaatgccat atttatgaga taattatctg ttacttgagg     4980

cattattttt tagattgcta tgatagaata accaggaggg agtgcatttt tctggaaaga     5040

tgatagaaac attgtattct agaaaagatt attggatact atggttttgt ttgtttgttt     5100

ttgttttttg tttttcgttt tttgtttgtt ttttttttga gacagagtct cgctctgtcg     5160

cccgggctgg agtgcagtgg cacgatctcg gctcactgca agctccgcct cccgggttca     5220

caccattctc ctgcctcagc cccccgagta ggtgggacta caggtgcccg ccaccacgcc     5280

cggctaattt tttgtatttt tcgtagagac ggggtttcac cgtgttagcc gggatggtct     5340

cgatctcctg acctcgtaat ccacccgcct cggcctccca aagtgctggg attacaggcg     5400

tgagccaccg cgcccggctt ggatactatg ttttttaaag gcatttcgta ccttttacgt     5460

attttctata agtcaacaag ctttaaacag tatttaaaac tatgttcaca tagtgccata     5520

agcactagaa agtcttagat gtcttctttc caagcctccc accatattaa aatttaaaat     5580

taaaaaacag aatccaaaac caaaatttaa atgagttctt caattttaac agcttcttac     5640

aagaatttct gattacaact tgtttcatac acccattgta gcagtaatgt ctcatatttc     5700

tcgttctctc agcacacact tacttggcca attggataat ccatctaccc tttgttcttc     5760

actgtaatct agaaatatag atttaactga acagctgtcc tttatccata tgttggttac     5820

cagttttcaa agagttagaa ttttaaaaat atatatttag ttaagcctgt gccttcaaga     5880

taacattagt ggagtggtta tactatcgac tatgttagga atggggggga gaaagtcagg     5940

ttcagtgatg tcaaattatg taaagttttt tttttgttcc tgtcttcaaa gttctgtatt     6000

agatgttctc ccatcatttt ttgagatgga gtcttgcagc ctacagtgca gtggcatgat     6060

attggctcac tgcaacctct gcctctcaac ctcaaacgat tctcctgcct cagcctcctg     6120

agtagctgcg actacaggca tgggccacca cacccagctc attttttaat ttatttttta     6180

tttttttagt aaggaagggt ttcaccatgt tggcaaggct ggtctcgaac tccttacttc     6240

aagtgatcca cccaccttgg ccttgcaaaa tgctgggatt ataggtgtga gccactcctc     6300

ctgaaatctt tctaaatctc actaatatat aattctagga ctactttaag cattcacttt     6360

ttctttaatt caagaaacat ttattgaaca cttatgtaca agctagtcta ctattggcta     6420

ttgttacttt gtttcaatga aggcagaaaa tggctagaag gattttaagc ctttttgtct     6480

cttgtataaa tctatacagg tccagtctct ctttgctcat attcaaattg aagtttgatc     6540

tttctccaaa aaatatccaa gccctgtgtt tgtcccagtt gaactaatat cttgattata     6600

tagtttaaga tcagtttgat aatgtctatt gaatatttac taaatgatta tgggatatta     6660

aattgagagc cttgggagct tatcatctag taaagatgaa caaaaaatgg tactatagtg     6720

aatgcaaata agctatcaaa aagtacaaac taagttggga gcttagaaga aattatgtaa     6780

gggaaggctt catagaaggg gtgacatttt ggtaaacctt ggaaaactga taggcagaaa     6840

taagggctgt atatcattct aagcaaaccc ttaaagtggg agcaagcagg atcaaaacca     6900

taatttggat tgatgacaga ctgcaaaaag tacattggag gaagatatga gtaggaaggt     6960

ttttgaaatc atgtcaatga atgggaagag agaaatggga gaatagcttg agaagttcaa     7020

ggtcaagggc tgctttgtcg agtacaaagg actcgagcat atttgaaatg aaaggtaata     7080

actgatctac tcttatggag caaccgagtt tcctgataga gatgtttatc tgggggaaaa     7140

aggcataagt caatcttctt ggagagaatg ggatcagaaa ctgacatatt gctacagagg     7200

ttacaaaagc tgtagtcaga gggcttcagt gttctggata tattaaagga caaggtcaga     7260

tacccaagtg ggaccgtgag tgattaatgg cagcagtcca ctgacagcac cagtaggaag     7320

gcgctaatga aaagatctct aaatatcagt aaggggttag ctgccattaa taatacaact     7380

ttatagcttt actatttttt cttttattgt tgaaatagtg agggcacgta tttttctaat     7440

tgtgtttatt acaaagaaaa cagacccgaa gaacttaaat gacttctcca aggtcacaca     7500

gctaatacat gacaatgtca tgacttaaaa tccagtcttg tggttccaaa tttagagctc     7560

tttcataaac ctgtctctag agaagcaagt cattttctac tttttccaga agcatttgaa     7620

gtggaagcta aggcaggaaa tgagaggata ttgtgttagt ctactgggat taccctggca     7680

aaataccaca ggctgggtag acaactgaaa tgtatttctc agttccagaa acaaagttgc     7740

agatcaaagt ttgttagggc tcagtttctg ggaagggctc tcttcctggc ttgtagataa     7800

taagctacct tctcactatg tactcacagg gcctttcttc tgttcatgca ctgagagatt     7860

tctttttctt gctcttctta taagaccacc agtgctattg gttaaagccc tgccattatg     7920

actttgtttg accttaatta cttcctaaag acactacctc ccaatacagt catgtttggg     7980

gttgggactt caacatatga atgttggagg ggatatggtt ctgtttctag caaatgtata     8040

gtagtgggaa ttgcaaaggt tgaagttcca aagtatcaag ggaatcagaa ttgggaagca     8100

attctaacct ttttgaagtg gttacatggc ccaagtagaa gagcaaataa ttccaagaga     8160

caccaagcca cagagcaggt aggatcacgt gagtagggcc caggatagaa gagcagtgtt     8220

agggttgcat gagagtgagg gcatataaga caacaacagc taaaagcaat gcatgctcag     8280

atcttgggag atgtattaaa tgagtagagt gaatttcaag atatctgagt tttttttttt     8340

taatgattac atgggttcta gagtcaaaat gccatggctc atctggtact gtaacttaag     8400

ataaactgct tagctaaggc tcagctttca tacctataat tttgttatac ttatcttgca     8460

ggtttcttga gaaatattgg atgaaataat tcatgtgaaa tgcttaacat atgtgtgaca     8520

aataattatc cttaaataaa tgttggtcgt tattacaatt ggctttgtta cttgattcag     8580

gcaggatcaa aattagctgc tatatgcatg actaaccagg accaaaaagt taataaaaat     8640

acgaaagttt ggcactctt                                                  8659


<210>  644
<211>  4811
<212>  DNA
<213>  homo sapiens

<400>  644
ggtggtgcca aattctgggg cctaggcatt tccctcgctt tatgtttttg gttttttttc       60

ttccttcaat ctctttgatt aggccgtacg tggctgtggc aaggagttgg ggaaaaaaat      120

tataaaaaca ggaaagagag aaagcacagc cagagccccg gcttcgcgag ccgccgggga      180

gggggcggag gaggctgagc caggcagagt cgccagcgga gactcgcgag tggcgcgcgg      240

gaggagcggc cgccggcgct gggcttgcct tgctgctgct gctgctgctg cctccccacc      300

gccttttttt ttttttaatc tggagcgggg tggggagtgg gaaccggaga gaaagcaaaa      360

tattaaaaag ccccaaagac agccagcagg agcgcggtgc ccgatggctt cgctgtacca      420

gaggttcact ggcaagatca acacctcgag gtccttcccc gcgcccccgg aggcgagtca      480

cctcctgggc ggccaggggc ccgaggagga cggcggcgca ggagccaagc ccctcggccc      540

gcgggcgcag gcggcggcgc cccgggagcg cggcggcggc ggcggcggcg cgggtggccg      600

gccccggttc cagtaccagg cgcggagcga tggtgacgag gaggacgagc tggtggggag      660

taaccctccg cagaggaatt ggaaaggaat agcaattgca ctgcttgtca ttctggtcat      720

ctgctccttg atcgtcacct cggtcatact tctgacacca gcggaagata atagtctgtc      780

tcaaaagaag aaggtcactg tagaagatct cttcagtgaa gacttcaaaa ttcatgaccc      840

cgaggctaag tggataagtg atacagaatt catctacaga gaacagaaag gaacagtgag      900

actgtggaat gttgaaacaa atacttctac tgtcttaata gaaggcaaaa aaattgaatc      960

attaagagcc atcagatatg aaatatctcc agatagagag tatgcacttt tttcatacaa     1020

tgtggaaccc atatatcaac actcgtatac tggatattac gtcctgagca aaattcctca     1080

tggggatcct caaagtctgg acccaccaga agtcagcaat gcaaaacttc agtatgcagg     1140

atggggccct aaaggccaac agctgatatt tatttttgaa aacaatatct actactgtgc     1200

acatgtcggg aaacaggcca tccgtgtggt ctccactggc aaggaaggtg tgatttacaa     1260

tggcctcagt gactggctgt atgaagagga gattttgaag acacacatcg cacactggtg     1320

gtctccggat ggcacgagac tcgcctacgc cgccatcaat gattcccgtg tccccatcat     1380

ggagctccca acttacaccg gctccatcta ccccaccgtg aagccctacc actatcccaa     1440

ggctggaagt gagaacccca gcatttccct acacgttatt ggcttaaatg gacccaccca     1500

tgatctggag atgatgccgc ctgatgatcc acggatgagg gagtactaca tcaccatggt     1560

gaagtgggcc accagcacca aggtcgccgt gacctggctg aaccgggcgc agaacgtgtc     1620

catcctcacc ctctgcgacg ccaccacggg ggtctgcacg aagaaacacg aggatgaaag     1680

tgaggcctgg ctccacagac agaatgaaga acctgtgttc tccaaggatg gccgaaagtt     1740

tttcttcatc agagccatcc cccagggagg acgagggaaa ttctatcaca tcacggtgtc     1800

ctcgtcccag cccaacagca gcaacgacaa catccagtcc atcacctccg gggactggga     1860

cgtgaccaag atcctagcct acgatgagaa ggggaataag atctacttcc tgagcacgga     1920

ggacctgcct cggagacgac aactctacag tgccaacacg gtgggcaact tcaacaggca     1980

gtgcctctcc tgtgacctgg ttgagaactg cacctacttc agcgcttcct tcagccatag     2040

catggacttc ttcctgctca agtgcgaagg tcctggtgtt cctatggtga cggtgcacaa     2100

cacaacagat aagaaaaaaa tgtttgacct agaaacaaat gaacatgtca agaaggccat     2160

aaatgaccga cagatgccta aagtggaata cagggacatt gagattgatg attacaacct     2220

gcccatgcag atactgaagc cagcaacctt caccgacacc acccactacc ctctgctcct     2280

ggtggtggat ggcaccccag gcagccagag tgtggctgag aagttcgagg tgagctggga     2340

gacggtgatg gtgagcagcc acggcgcggt ggtggtaaag tgtgacggcc gtggcagcgg     2400

cttccaaggg accaagctcc tgcacgaagt gaggcggcgg ctgggcttgc tggaggagaa     2460

ggaccagatg gaggccgtgc ggacgatgct gaaggagcag tacattgaca ggacgcgcgt     2520

ggccgtgttt gggaaggatt acggtggcta cctgagcacc tacatcctcc cagcaaaggg     2580

agaaaatcaa ggccagacat tcacctgcgg ctctgctctc tctccaataa cagacttcaa     2640

actctatgcc tctgcgtttt ccgagaggta cttgggcctc catggacttg acaacagagc     2700

atacgagatg accaaggtag cccatcgagt ctccgcgctg gaagaacagc agttcctgat     2760

cattcatccc actgccgatg aaaaaattca tttccagcac acagcagaac tcattacaca     2820

actaattagg ggaaaggcta attacagctt acagatttac ccggacgaaa gccattactt     2880

taccagctcc agcctcaaac agcatctgta ccggtccatc atcaacttct tcgtggaatg     2940

cttcaggatc caggacaaac tgctgacagt cacagcgaaa gaggacgagg aggaggacta     3000

agctcaggtc gctctaagca caaacgtggc tctttctaca accagatgca accgagggat     3060

ttccctgccc tccctcttcc ctcggagggg cggggcgggg cggggccggg tgttccatag     3120

catgtgtgtc tcggatgcgg aaggcagttt tgcttgggaa acaagctcct tccccggggt     3180

catcactcac ggcctccatg gcaccaggga caacgctgtc cccgcagcag cgcctcctcc     3240

cggcgcccga gagaccggca cgccacggcc cctcccccaa ggaacagagc aaaggatggt     3300

ggccgcaggc cccacgcgag cccacaggac accggcccct agattccagc caccaagcgg     3360

aagcatgaga cccgcccaca ctagcctctg tgttcccgtt agggacatca caccctgtct     3420

cacgtcgcag tgccatggac gcagcagtta cagcaccatt gttttagcag tgcgtgttca     3480

tatatgggct tgctacttcc tgtaatgagg acgttcaaca tggtgagggg ctacaagaaa     3540

acgcttttct gtacagagtc ttactgtagc tacgctaatg gttaacctga tagaattaac     3600

tcgtattttt ctatggtttt aacctgatgc tccactgtct ccgtcatggg gttgttttgc     3660

tgtttggggt tgggccttgt ttccctttcc tttctccagt ccacgtgtag actttgcgct     3720

tgatgaagaa gcagatcgga agtaactgct ccctcctcaa ggttgtcttc agacgtcttg     3780

gggacgttcc taaacactga gggggaagac agccaatagc acccattaaa agaaatacct     3840

aaataaaacc tctctcccac tcagctatgc tagggcttgg ctgtaggtgt gcactgtcta     3900

tttacatccg tccttacaac catccttgtc ctccttggta ccgtatcaag ctctttccca     3960

tgacatttgg tttaaaaaaa aaaaaaaaaa aaaaaaaaaa acagaaaaaa gacaaagcgt     4020

caactccacc cacaggcccg ctgtgtgtgc tcgggccacg ggagtcctga gggttctgtg     4080

ggcctgcgcg catccctctc ccatcgtggg ggtggctccg tgaccttcct gccacgagca     4140

ggaggttgat gatgtgctac gttagccttg taagatacac ccccaccaaa tgtgcagccg     4200

gtgttcccag tgtatatttc attctcttgt atataaagga agcaatgtgt gtcaggcctc     4260

tgtgcagtca acccagcctc ctcccgccag tgctaacccc gtgttgagcc tgcatgctga     4320

cactgtggcc gatctggact ctagaagtgc tagtttgaaa tatatccatt actgtcattt     4380

ccttttgagc ttgtggacaa gctgaatgtc aggactgact tcgccagctc ccagccctgc     4440

gggggtgtcc ttggcatccc atcagcagag gagatgcgtc cctgttgcat tttggcgttt     4500

ggggctttgg gtttatccac atgagctctg aacgtccgtt atagttaggg tgattggaag     4560

gtctccatca ctgggtgttt taaaggtgat tcaccaccat ttgtgaaagg accaacgtgc     4620

tgataaacag gaccgatccg agtgctacat gactgtgcgt ttgctatttc aatgggcctg     4680

aacgactaca aagccagcta ggtctggaag gggaagccag ctctggccac gacatctggt     4740

cggagggaag tggggatgtg gcatggtagc gtctgttcat ccatggaata aaacattatt     4800

ttaccactcg g                                                          4811


<210>  645
<211>  3154
<212>  DNA
<213>  homo sapiens

<400>  645
gagctcgccg tcgctccgtc atagagttcg ccccacccca tcccctcctt tctggactcg       60

gagctcagtt cacgcagtaa caaatgaagt gcgcgctgcg acacctccca gcccaccgaa      120

ctccgccgcc atttcctcgc ttggcctaac ggttcggcca atcccagcgc gcatcaagaa      180

ggactgaggc tccgccaatc ggaggccgcc gatttcgacc cttcgcctcg gcccggccca      240

atccaggccc cggccccgcc gcccccggcc cgcccccgcg gtgccctctc tcctccctct      300

ttgtgcgtct cgcgccgccg ccgcccgccg cgtgagagga cgggctccgc gcgctccggc      360

agcgcattcg ggtcccctcc ccccgggagg cttgcgaagg agaagccgcc gcagaggaaa      420

agcaggtgcc ggtgcctgtc cccgggggcg ccatggcgac cggagcgaac gccacgccgt      480

tggacttccc aagtaagaag cggaagagga gccgctggaa ccaagacaca atggaacaga      540

agacagtgat tccaggaatg cctacagtta ttccccctgg acttactcga gaacaagaaa      600

gagcttatat agtgcaactg cagatagaag acctgactcg taaactgcgc acaggagacc      660

tgggcatccc ccctaaccct gaggacaggt ccccttcccc tgagcccatc tacaatagcg      720

aggggaagcg gcttaacacc cgagagttcc gcacccgcaa aaagctggaa gaggagcggc      780

acaacctcat cacagagatg gttgcactca atccggattt caagccacct gcagattaca      840

aacctccagc aacacgtgtg agtgataaag tcatgattcc acaagatgag tacccagaaa      900

tcaactttgt ggggctgctc atcgggccca gagggaacac cctgaagaac atagagaagg      960

agtgcaatgc caagattatg atccggggga aagggtctgt gaaagaaggg aaggttgggc     1020

gcaaagatgg ccagatgttg ccaggagaag atgagccact tcatgccctg gttactgcca     1080

atacaatgga gaacgtcaaa aaggcagtgg aacagataag aaacatcctg aagcagggta     1140

tcgagactcc agaggaccag aatgatctac ggaagatgca gcttcgggag ttggctcgct     1200

taaatgggac ccttcgggaa gacgataaca ggatcttaag accctggcag agctcagaga     1260

cccgcagcat taccaacacc acagtgtgta ccaagtgtgg aggggctggc cacattgctt     1320

cagactgtaa attccaaagg cctggtgatc ctcagtcagc tcaggataaa gcacggatgg     1380

ataaagaata tttgtccctc atggctgaac tgggtgaagc acctgtccca gcatctgtgg     1440

gctccacctc tgggcctgcc accacacccc tggccagcgc acctcgtcct gctgctcccg     1500

ccaacaaccc acctccaccg tctctcatgt ctaccaccca gagccgccca ccctggatga     1560

attctggccc ttcagagagt cggccctacc acggcatgca tggaggtggt cctggtgggc     1620

ccggaggtgg cccccacagc ttcccacacc cattacccag cctgacaggt gggcatggtg     1680

gacatcccat gcagcacaac cccaatggac ccccaccccc ttggatgcag ccaccaccac     1740

caccgatgaa ccagggcccc caccctcctg ggcaccatgg ccctcctcca atggatcagt     1800

acctgggaag tacgcctgtg ggctctgggg tctatcgcct gcatcaagga aaaggtatga     1860

tgccgccacc acctatgggc atgatgccgc cgccgccgcc gcctcccagt gggcagcccc     1920

caccccctcc ctctggtcct cttcccccat ggcaacaaca gcagcagcag cctccgccac     1980

cccctccgcc cagcagcagt atggcttcca gtaccccctt gccatggcag caaaatacga     2040

cgactaccac cacgagcgct ggcacagggt ccatcccgcc atggcaacag cagcaggcgg     2100

ctgccgcagc ttctccagga gcccctcaga tgcaaggcaa ccccactatg gtgcccctgc     2160

cccccggggt ccagccgcct ctgccgcctg gggcccctcc ccctccgccg cctccaccgc     2220

ctggttccgc cggcatgatg atccctcccc gcggcggcga tggcccgagc catgagagtg     2280

aggactttcc gcgcccattg gtgacccttc caggcagaca gcctcagcaa cgcccctggt     2340

ggacaggatg gttcggcaaa gcagcctgag ttatttttgt ggacggaatc ggaacacgct     2400

ggctccatat cgtgaaattt ttattaattt ttttcttttt cctttgttac ttctttatct     2460

tttcctttct tcagactccg tccaaggaga tgctctcccc ggtcttctgc tgcaatttag     2520

attcctttcc cttctctcca gttctccttc ccttaccaag gagaggggag caaatggttt     2580

tgggcaaggg ctttggccat tcatgtcaag ctggttgtgg gtttttcaag gtgccatagc     2640

cacccccaaa gatgtttgtt taaagcgtgg ggttttttaa tctctgccac ccttgtcaag     2700

ggagtcttgt aaagttgccg agggtaggtt catctccagg tttcgggatt cccatccgtc     2760

ctggcgatcc tgccagcagt gggtgggcag cctgagctcc ctcgggctcg cctgccagcc     2820

tggagttctt cctgtgctcc ttgatcacct gagctgcctc agattccatt tggtcctctc     2880

cttcctggaa ggcttccttt tatgttttgt tttaatccca aatgtctgaa tgttttgcag     2940

tgtgtagggg tttgagcccc ttgttcattc tccttccttt ttcctcccgc ttccctctcc     3000

atgaagtgat tctgttgaca ataatgtata ctgcgcgttc tcttcactgg tttatctgca     3060

gaaatttctc tgggcttttt tcggtgttag attcaacact gcgctaaagc ggggatgttc     3120

cattgaataa aagagcagtg tggttttctg ggtc                                 3154


<210>  646
<211>  2849
<212>  DNA
<213>  homo sapiens

<400>  646
tcctcctcct ctcttctctc ttacctccct ccctctctct catctttatc ccttcctctc       60

ttttctgttc gccctcttct ccctgctctt tttccctttc cacccccctc ctctgttctc      120

cctcacctcc tgcgccccct cccccttccc gggttctgac agtacgatga gctgccccat      180

tacggcggga tggacggagt aggggttccc gcttccatgt acggagaccc tcacgcgccg      240

cggccgatcc ccccggttca ccacctgaac cacgggccgc cgctccacgc cacacagcac      300

tacggcgcgc acgccccgca ccccaatgtc atgccggcca gtatgggatc cgctgtcaac      360

gacgccttga agcgggacaa ggacgcgatc tatgggcacc cgttgtttcc tctgttagct      420

ctggtctttg agaagtgcga gctggcgacc tgcactcccc gggaacctgg agtggctggc      480

ggagacgtct gctcctccga ctccttcaac gaggacatcg cggtcttcgc caagcaggtt      540

cgcgccgaaa agccactttt ttcctcaaat ccagagctgg acaatttgat gatacaagca      600

atacaagtac taaggtttca tcttttggag ttagaaaagg tccacgaact gtgcgataac      660

ttctgccacc gatacattag ctgtttgaag gggaaaatgc ccatcgacct cgtcattgat      720

gaaagagacg gcagctccaa gtcagatcat gaagaacttt caggctcctc cacaaatctc      780

gctgaccata acccttcttc ttggcgagac cacgatgatg caacctcaac ccactcagca      840

ggcaccccag ggccctccag tgggggccat gcttcccaga gcggagacaa cagcagtgag      900

caaggggatg gtttagacaa cagtgtagct tcacctggta caggtgacga tgatgatccg      960

gataaggaca aaaaacgcca gaagaaaaga ggcattttcc ccaaagtagc aacaaatatc     1020

atgagagcat ggctcttcca gcatctcaca catccgtacc cttccgaaga gcagaagaaa     1080

cagttagcgc aagacacagg acttacaatt ctccaagtaa acaactggtt tattaatgcc     1140

agaagaagaa tagtacagcc catgattgac cagtcaaatc gagcaggttt tcttcttgat     1200

ccttcagtga gccaaggagc agcatatagt ccagagggtc agcccatggg gagctttgtg     1260

ttggatggtc agcaacacat ggggatccgg cctgcaggac ctatgagtgg aatgggcatg     1320

aatatgggca tggatgggca atggcactac atgtaacctt catcatgtaa agcaatcgca     1380

aagcaagggg gaagtttgca gagcatgcca ggggactacg tttctcaggg tggtcctatg     1440

ggaatgagta tggcacagcc aagttacact cctccccaga tgaccccaca ccctactcaa     1500

ttaagacatg gacccccaat gcattcatat ttgccaagcc atccccacca cccagccatg     1560

atgatgcacg gaggaccccc tacccaccct ggaatgacta tgtcagcaca gagccccaca     1620

atgttaaatt ctgtagatcc caatgttggc ggacaggtta tggacattca tgcccaatag     1680

tataagggaa ctcaagggaa aaggaaacac acgcaaaaac tattttaaga ctttctgaac     1740

tttgaccaga tgttgacact taatatgaaa ttccagacag ctgtgattat tttttacttt     1800

tgtcattttt catcaagcaa cagaggacca atgcaacaag aacacaaatg tgaaatcatg     1860

ggctgactga gacaattctg tccatgtaaa gatcctctgg aaaaagactc cgagagttat     1920

aactactgta gtataaatat aggaactaag ttaaacttgt acatttctgt tgatcacgcc     1980

gttatgttgc ctcaaatagt tttagaagag aaaaaaaaat atatccttgt tttccacact     2040

atgtgtgttg ttcccaaaag aatgactgtt ttggttcatc agtgaattca ccatccagga     2100

gagactgtgg tatatatttt aaacctgttg ggccaatgag aaaagaacca cactggagat     2160

catgatgaac ttttggctga acctcatcac tcgaactcca gcttcaagaa tgtgttttca     2220

tgcccggcct ttgttcctcc ataaatgtgt cctttagttt caaacagatc tttatagttc     2280

gtgcttcata agccaattct tattattatt tttgggggac tcttcttcaa agagcttgcc     2340

aatgaagatt taaagacaga gcaggagctt cttccaggag ttctgagcct tggttgtgga     2400

caaaacaatc ttaagttggg cagctttcct caacacaaaa aaaagttatt aatggtcatt     2460

gaaccataac taggacttta tcagaaactc aaagcttggg ggataaaaag gagcaagaga     2520

atactgtaac aaacttcgta cagagttcgg tctattaatt gtttcatgtt agatattcta     2580

tgtgtttacc tcaattgaaa aaaaaaagaa tgtttttgct agtatcagat ctgctgtgga     2640

attggtattg tatgtccatg aattcttctt ttctcagcac gtgttcctca ctagaagaaa     2700

atgctgttac ctttaagctt tgtcaaattt acattaaaat acttgtatga ggactgtgac     2760

gttatgttaa aaaaaaaaag gtgttaagtc acaaaaagcg gtaataaata tttcattttt     2820

gattttttgt taaaaaaaaa aaaaaaaaa                                       2849


<210>  647
<211>  10836
<212>  DNA
<213>  homo sapiens

<400>  647
ggcagaactt tggcgggcaa ggagacaaac agccacactg tgctgccggg gaagagaaga       60

agaaggaaag gccagacaca caggcgtcgt gcagctgcgg aaggattccg tttcctgcag      120

ggggcggagg gatttgacag cacggtaact tccggaaaag tcctgaacct cagtggaaaa      180

gccttgcaag aaacaataac aaacgggagg aggaagcgat tctggggttt ctgtgttgaa      240

cggttcttgt ccgcgaagat gcgcttcggc ctctgtcagg ggacttgaac gggcttagtg      300

ggcttcagcc agcttttctc caccggttcc ccacggggac cccccccccc ccccggccgt      360

tgcaatggcg ggcgtggggc cggggggcta cgcggcggag ttcgtgccac cgccagagtg      420

ccccgtcttt gagccgagtt gggaggagtt cacagatccg ctcagcttta tcggccgcat      480

ccggcctttg gcggagaaaa ccggcatctg caaaattcgg ccgcccaagg actggcagcc      540

tccatttgcc tgtgaagtaa aaagctttcg tttcactcca agagtccagc gcctgaatga      600

acttgaggca atgaccagag tgagattgga tttcttggat caactagcaa aattttggga      660

acttcaagga tctactctga agatccctgt ggtagagaga aaaatcctgg atctgtatgc      720

tttgagcaag attgttgcca gcaaaggagg ttttgaaatg gtcaccaaag agaagaaatg      780

gtctaaagtg ggtagtcgct tgggatatct gccaggaaaa ggaactgggt ctcttttgaa      840

gtcacattat gaaagaattc tctacccata tgagcttttc cagtctggtg tgagccttat      900

gggtgtgcag atgcctaatt tagatcttaa agaaaaagtg gagcctgagg ttctcagcac      960

tgatacccaa acttccccag agccaggcac aaggatgaac attctgccga agagaacaag     1020

acgtgtgaag actcagtcag aatctggaga tgtgagtaga aacacggaac tgaagaaact     1080

tcagattttt ggggctgggc ccaaggttgt gggcttggca atgggaacaa aagataaaga     1140

agatgaggtc acccgaagac gaaaagttac caacaggtca gacgcattta acatgcaaat     1200

gagacaacgg aaaggcactc tctctgttaa ctttgttgat ctctatgttt gtatgttttg     1260

tggtcgggga aacaatgaag ataaattgct tttgtgtgat ggatgtgatg acagctatca     1320

tacattttgt ctaattcctc cactacctga tgtgcccaaa ggagactgga ggtgtcctaa     1380

atgtgtcgcc gaggaatgta gcaaacctcg agaagccttt ggatttgaac aagctgtacg     1440

agagtataca cttcagagct ttggagagat ggcagataat tttaagtctg attattttaa     1500

tatgccagtc catatggttc ccacagaact agtagaaaag gaattttggc ggctggtaag     1560

cagcattgaa gaagatgtta ttgtggaata tggagcagat atctcctcaa aagactttgg     1620

aagtggattt ccggtgaagg atgggcggag aaagattctg ccagaagaag aggaatatgc     1680

actttctggt tggaatttga ataacatgcc tgtcctggaa cagtctgttc ttgcacatat     1740

taatgtggac atctctggta tgaaagtgcc gtggctctat gtgggaatgt gcttctcttc     1800

tttttgctgg cacattgagg atcactggag ttattccatc aactacttgc actgggggga     1860

gccaaagaca tggtatggtg tgccatctca tgctgcagag caactggagg aggtgatgag     1920

agagctggcc cccgagttat ttgaatccca gcctgatctt ctgcatcagt tagttaccat     1980

catgaacccc aacgtgctaa tggagcatgg tgtgcctgtg tacaggacca atcagtgtgc     2040

tggcgagttt gttgtgacat ttcctcgtgc ctatcactct ggatttaacc agggctacaa     2100

ctttgctgaa gctgtgaact tctgtactgc tgactggttg cccattggac gtcaatgtgt     2160

aaatcattac cgacgcctaa ggcgccactg tgtcttttca cacgaggaac taattttcaa     2220

gatggcagca gatccagaat gcttagatgt ggggctggct gccatggtct gcaaagaatt     2280

gactctcatg actgaagaag aaacacgatt aagagagtct gttgtacaga tgggtgtcct     2340

gatgtcagaa gaagaagtgt ttgaacttgt tcctgatgat gagcggcagt gttcagcatg     2400

cagaaccaca tgttttctct ctgctctcac atgttcctgt aatcctgagc ggcttgtatg     2460

tctctaccat ccaactgatc tgtgcccctg ccccatgcag aagaaatgtc ttagatatcg     2520

ctacccatta gaagacctcc cttctctgct atatggtgta aaagtcaggg cacagtccta     2580

tgacacttgg gtcagtcgtg ttacagaagc attgtctgct aacttcaacc acaaaaaaga     2640

tttgattgaa ttgcgagtaa tgctggaaga tgctgaggat aggaaatacc cagagaatga     2700

tctctttcga aaactcaggg atgctgtaaa agaagctgag acctgtgctt ctgtggctca     2760

gctgcttctg agcaaaaagc agaaacacag acagagccca gatagtggga ggactcggac     2820

caaactgaca gtggaagaat tgaaggcctt tgtccaacaa ctttttagtc ttccgtgtgt     2880

catcagccaa gctcggcaag taaagaatct gctagatgat gtggaagagt ttcatgaacg     2940

tgctcaggag gccatgatgg atgaaacccc agattcttcc aaactccaga tgttgataga     3000

tatgggctct agtctctatg tggaactccc tgaattacca cgactgaagc aagagctaca     3060

acaggctcgg tggttggacg aagtaagact gaccttatca gatccgcaac aagtcacttt     3120

ggatgtcatg aagaagctga tagactctgg ggtagggttg gcaccccacc atgctgtgga     3180

gaaagcaatg gctgaactac aggagctcct tacagtctct gaacgatggg aagaaaaggc     3240

taaggtctgc ctacaggcaa gaccgaggca cagtgtggca agtttagaaa gcattgtgaa     3300

tgaagccaag aacattccag cctttctacc caatgtgttg tccttgaaag aagccttaca     3360

aaaggctcga gaatggaccg ctaaagtgga agctattcag agtggcagca attacgctta     3420

tttggagcag cttgagagct tgtctgcgaa aggacgccct attcctgtgc gtcttgaagc     3480

actgccgcaa gtggaatcac aggtagcagc agcacgggca tggagagaac ggactgggcg     3540

gacgtttctt aagaagaatt ctagccatac attgttacag gtgctgagcc cccggaccga     3600

cattggtgta tatgggagtg gcaaaaatag gaggaaaaaa gtaaaagaac taatagaaaa     3660

agaaaaagaa aaggatctgg acctggagcc tctgagtgat ctggaggaag gattggagga     3720

aaccagagat acagccatgg tggtggcagt tttcaaagaa cgggagcaaa aagagattga     3780

agccatgcat tctctcagag cagccaacct agccaagatg acaatggtgg accgcataga     3840

agaagtaaaa ttttgcattt gccgcaagac agccagtggg tttatgctac agtgtgagct     3900

ctgcaaagac tggttccata acagctgtgt tcctcttcct aaatcaagtt cccaaaaaaa     3960

aggatccagc tggcaagcta aagaagtaaa attcctttgc cctctttgta tgcggtctcg     4020

aaggcccagg ctagagacta ttctgtcact cctggtatcc cttcagaagt tgcccgtacg     4080

gttgcctgaa ggagaggccc tgcagtgttt gacagaacgt gctatgagtt ggcaagatag     4140

agcgcggcag gctctagcca cagatgaact atcctctgcc ctggccaaac tatctgtgtt     4200

gagccagcgt atggtggaac aggcggctcg agaaaaaact gaaaagatca tcagtgcaga     4260

actccaaaaa gcagctgcca atccagactt acagggacac ttacctagtt tccagcagtc     4320

tgcttttaac cgggtggtga gcagtgtgtc atcttctcct cgacaaacaa tggactatga     4380

tgatgaagaa acagactctg atgaagacat tcgagagaca tatggctacg acatgaagga     4440

cacagccagt gtgaagtcct ctagtagtct tgaacccaat cttttttgtg atgaagagat     4500

tcccatcaaa tccgaggagg tggtgaccca catgtggaca gcaccttcat tttgtgcaga     4560

gcatgcttat tcttctgctt ctaagagttg ttctcaaggt tctagcaccc caaggaaaca     4620

acctcggaag agccctttgg tgccccgaag tttggaacct ccagtgctgg agttgtcacc     4680

tggagctaag gcacaactgg aagaacttat gatggttgga gatctcctgg aagtatctct     4740

ggacgagact caacacatat ggcggatttt gcaggccaca cacccaccct ctgaagacag     4800

attcttgcat atcatggagg atgacagcat ggaagagaaa ccactaaaag tgaaaggaaa     4860

ggactcttca gagaagaaac ggaaacggaa gctagaaaag gtagagcaac tttttggaga     4920

aggaaaacag aagtccaagg agttaaagaa aatggacaaa cctagaaaga agaaattaaa     4980

attaggtgca gacaaatcaa aggagctgaa taaactggcc aagaaactag caaaagaaga     5040

agagagaaag aaaaagaagg agaaggctgc tgcagccaaa gttgaacttg tgaaagagag     5100

cactgaaaag aaaagagaga aaaaggtgct ggacatcccc tcaaagtatg actggtcagg     5160

agcagaggag tctgatgatg agaatgctgt gtgcgcagca cagaactgcc aaaggccctg     5220

caaggacaag gtagactggg tacaatgtga tggtggctgt gatgagtggt ttcatcaagt     5280

ttgtgtgggt gtatctccag aaatggctga aaatgaagat tacatctgta taaactgtgc     5340

aaagaagcag gggccagtta gcccaggtcc agcaccacct ccttccttca taatgagcta     5400

caaactacca atggaggatc ttaaagagac cagttagcag atgcttggtt agtttgggac     5460

atggggggac atggaccaca ttgagacctt agtcatcaag tagagtggtt tatatccact     5520

tggaatgttg cttccaaaga tgaatggcct tcagagaaag tccccttagt gctggcttcc     5580

tctttgcatg gactctgtgg gttacattct ctatcaacat atctatgcag agggtgtctt     5640

ctttggtaca acagccaata tttcatgtct cctttgagtg tggtttactg cattaaggcc     5700

agatgcttaa ttgagctcta gggtggctgg ttagtattaa tacattggtg tgctaacagg     5760

gcatatagga tgtggctttt gtccagctga tagtagttag aggcttacaa cttaggagca     5820

gcaccaactg aaggtgctaa ttgcttggat ctccttcatt gggatagttg gagagggatt     5880

ggagtaccac tttccttcca ctgttacctg gtacttaatg ccctaaagat acaactagga     5940

gtaacagggc caaagttatt tctgttagac gtcaaggaat ggtatcacag tctattgacc     6000

tcagcgattt gtgcttgttt gtgctagaag aacatcccaa ataggagaac ctctcacaag     6060

ctggggcagg tcaccttatc tttgtaagat gaggatatca tctagatcag aaatctgact     6120

agattggatt ctgaggagaa gaacctacta caaggcaagg agccgttttt tggctttgaa     6180

aagtcttgct gtcttgggtc tacattttag ggaagagcag gtacatggat ccaggcttct     6240

gccaaaaaaa aaaagagaag aagatgacga tgatgaccag tcgtactatc ttactgagcc     6300

acagtgatgc atgcttttcg gggaaaactt cattcacaag tattccagac accaggcttc     6360

aggcatggcc atgagcaaga ccagcaaata acagcttttt gccttgcagc cctgacccca     6420

atgtctgctg tttccaacac tggtgatttc taactacggc ccacagcaga tgctgttgaa     6480

taacaccatg gcttcatcag aggatgtggg gttgtagtac ctctgggtga tgaagttgtt     6540

ttagtaaatc catttttaaa aaaaaaaaag gacttgtttt tacttttttc taaatgtctc     6600

tgactactga ctgttctata catagattat ttttcctttt ttaatataca tatatgaata     6660

tataaatata tatatttact gttaccagca gcatatgaca gagtttcaac atcaaaaatc     6720

catttggggg cttgcttttt cttttttgct ttaaaaaaaa aaatcccatt ccttctttgt     6780

agtacaagga gttagcactc cctcctccat cccagcctga ccagatcttc cattttgctt     6840

ttgttcatat agataattat atgtcctttg tgtgttggga cttgtccctg tctgttggga     6900

aacttggtct cactctagtc tgtgctggct cttttttctt ttgtgtgtga atgtttgaaa     6960

ctatggtgct gtgtcctctt ccctcctgtt gtgttctctg ttcttcttaa ggtattaggt     7020

aagctgtatg taaactctta ttagaagggg actaattttt ttttaaagga caaaaaaaaa     7080

aatgactaaa aatagtgttt tgtcatcact gtctggtgtc tttattttgg tttaaaaaaa     7140

tctgtggttt gacttaaatt catcagtttt ccttttaaag gggggattgg ggtggaccta     7200

gcaacagctt atagtttcct cttccctttt tgccccagtc tcttttaaag aactgtcttc     7260

tagtaactag aagtgaaatg tactgtccag ttacagtttg agtgggtatg agatttaact     7320

caaaaggaat cttacaaaaa aaaagatgtt ttcttataaa atccaatttc tgtaaatgtt     7380

ttctctgaag ttcatactac ctacttttta ttcattctta atactgtata acattttgag     7440

tgttttgact tgttcagagg tttgttagtg ttgctgtgca tatgtcttga ggtctcatct     7500

gaagtaagtt tgtgtatgat cgaagatttc aatggatatt gcaaggtaac taattaactg     7560

atttcataag ttttcgtttt gccaagctaa cgattatcaa ttaagaattt cctctggttg     7620

atgttataca agaaagcaca atattttttg cctgttgatc ttctttgtaa cagtcttcag     7680

atatttgtgg gttaaaaatt gaatgtaatt ttaagtgaca gatgcctgga atacatttaa     7740

aatttttatt tttccttcct aatcatccat taactattcc actatcagtg gagagtcatg     7800

aggatgctga gaaagtatga atagcttcct gtcaccttct gacgttttga aacttaaata     7860

tgtcttttcg ttgatactgt gggattttct gtatttactt gacagtcatg gaggatttgg     7920

tatgacttga ccacaggttt agaccaaggc tgagaagaac agaagggaga aattaatggc     7980

aaaacaaaaa atacacaaat ctgcggtttt ggaattaatg aaacaagatt catctattta     8040

aagaaatgtt ggtgttctaa tacaaagcat tattttcact tagagaaaat tacttacttg     8100

ctcccttctg tattgtaata ttttgtatta agacatgatt taaaatgtct ttctaccctt     8160

atctcctcta aactgcaact gaagttgcaa ttcttcatca ttagtatttt aactctggca     8220

aaggttatag aaagaaaaat ggaaatatgg taggcctgtg gtattcttaa aagctaagtc     8280

attagaacta tgcagatccc caagtttaaa agtacaaata cagcaccagt agttagcttt     8340

ctagctgggg gagaagacag gagatttttc ttccacagat gtttattttg cttcctgata     8400

ggtactgcag caaagccatg ttgatgtgta gatgcatgac ttcctcacta agctgctgca     8460

caccagcttt gcctgcatga ttcaaatttg tgcctcagta aaattataaa ttattgcatg     8520

tcataccttg aataatggaa acggcaaaca ttaaacctgt gattacccat aatgtacttt     8580

aataataaaa aacatggcag ccaggtgcag tagagtgcac ctgtggtcag gaggctgaag     8640

tgggaagatt gcttcaacct gtgagtttga gtcccgcctg gtcaacagcg agaccccatg     8700

tgtctgtctg tctctctctt tttttaaagg acagaggcta agctgtaagg ttagcatggt     8760

tctgcctggg ctttgcttct gtgcttctgt gcaggctgag ctgtaaggtt agcatggttc     8820

tgcctgggct ttgcttctgc gcttctgtgc aggctgagct gtaaggttag catggttctg     8880

cctgggcttt gcttctgcgc ttctgtgcag gctgagctgt aaggttagca tggttctgcc     8940

tgggctttgc ttctgcgctt ctgtgctagc aggtgcccac aaaatgtctt tttgaatttc     9000

ttaatttttg ggttctggat gcaattcgtg cacgccaaga aactacttgc ttgtcagtat     9060

tttaattctg tagtacatgt gtgtgaatat cagccagtac ttacagtagg aggatgaaca     9120

gaaaaactga gaagacctgt ctttcaaaag atgggtttat ccacttttta agggaaaaag     9180

tgacagtttg gcatgggatt tgaaaagtgg aaattgtgga aaaattgagc tgttgaagtc     9240

ccacatataa ccagatttaa taaagcttca catgtgaatt agctccatat gtgtgtagaa     9300

ggttgctttt atagcaggtc cttaagtact ccttttgaaa ttcctccttt ttttttaagt     9360

cataccatta cttctttgga tatgaatgtc ccaagtggta tctcctactg tagtatgagg     9420

aagaatggct gttaatgtat tttttgaatt ttggtcttgt cttggcctgg atcatatcca     9480

gtcaccacta tgcaacaaat gatgtgcact gggcaaggat atgatgggtt atgaaagctg     9540

tatcttgttt gttttttctt ttgcagtact ccaagtggtc taaacaggaa tgtcttgtaa     9600

aacctcaaga ctccctattg attattccct tacatattta tttacaattt atcagggtaa     9660

ttggtggtgc cttatgaaaa gtataactcg atttcttgat ctttgagcat gttttgtgtt     9720

tcttgtgttt tctaaaagaa tattagatat ggttaattgc attacatcta aaagatttaa     9780

aaaattgtgt gtatgctcag gttccccaca cccataccca ccctaacccc tgtcatttac     9840

attggtggca actttaaatg gtaaccaagc aaaagtacat tttgataatg agtattgata     9900

atcctgagga aaactagtga gtatatggga gccacctttg acctgtgcca aagcagtttc     9960

taatttcatt tgctaactat aaaataaaga actgagccaa aataatttga tcagtggtgt    10020

gattagccta ttatcattgc tgagaatagt gtttttggag tgtgaagtga ttcctgaaga    10080

tttcacctgc cttctgtttc cagcaagaat ccagtgatga ccaacacatt tcctcacttt    10140

tggttcttga gaagtttatc cctttgcaac aaaccattaa tagggaaaac aaggaaatgc    10200

tttccctttc tctttggctt cttaaagctc acaaccaatt cagaccccaa gttacttcag    10260

agaagcaaat ggcacctttt ccccattgcc aaggatccca gcttatgcag atatgaagga    10320

cggatcattt ctgaaaatgt taagactctg cttgcagtgg acttggcctc agtttcatga    10380

aatgtgtaac tctgtatgtg tatgttagga ggagggttgg ttgaaagagc gggggcaggg    10440

aggggaatct gattacctct tgggaaataa ttttcttgcc aacaaaaaga tacacttgaa    10500

gtttcttaag gtggcaagtc cattaaaaaa aaaaattgtg ttggaccctc ccagtttaga    10560

tcaagtattt cttgggggtc ttgctattgt ggttgatacc aataaatgga agatccagaa    10620

tattttcatt taaagctcaa ccattaattg gaacatggtg aaacattgta cacattgtaa    10680

aagtagggaa cagtacaaaa gaatggaatc aaatactata ttatgtgaat aaactagagt    10740

gattttggaa tttcactctc ttcacccctt ctcacttgta tgttctgtaa agtgtatttc    10800

tactttggta ggaagaaaga cttgatttaa tatttc                              10836


<210>  648
<211>  2594
<212>  DNA
<213>  homo sapiens

<400>  648
agccttcccc tggctccatg ggtttccccc tcccctgttg tatctaccct gccccagctc       60

ttccctgccc acccctcgct gactcgcttc gcttccccga cgcgctgggt tcccggagcg      120

cagagcccag cgttagcggg tgggctcccc gaggccccct gccctcgccg ggctgctcca      180

gggtgtcgct cctctggctg ctcccgaagg ggcttctggc cctgaggacg gtggtgccaa      240

gcgaacttca tttttaaaaa gaactggtgg atgagaagag cgagcgaggg cgagctatgg      300

accctgtgag tcagctggcc tctgcgggca ccttccgggt gctgaaggag ccccttgcct      360

tcctgcgagc cctggaattg ctttttgcaa tctttgcatt tgcaacatgc ggtggctatt      420

ctggaggcct gcggctgagt gtggactgcg tcaacaagac agaaagtaac ctcagcatcg      480

acatagcgtt tgcctaccca ttcaggttgc accaggtgac gtttgaggtg cccacctgcg      540

agggaaagga acggcagaag ctggcattga ttggtgactc ctcgtcttca gcagagttct      600

tcgtcactgt tgctgtcttc gccttcctct actctttggc tgccactgtc gtttacattt      660

tcttccagaa caaataccgg gaaaacaacc ggggcccact cattgacttc attgtcactg      720

tagtcttttc gttcttgtgg ttggtgggtt catcagcttg ggcaaaagga ctgtctgacg      780

tcaaagttgc aacggatccc aaggaagtat tgctactaat gtcagcttgc aaacagccat      840

ccaacaaatg catggctatc cacagccctg ttatgtcaag cttaaacact tctgtggtct      900

ttggattctt gaactttatt ctctgggctg gaaacatatg gtttgttttc aaggagaccg      960

gctggcattc ttcgggacag agatatcttt cagatccaat ggagaagcac tccagcagct     1020

ataatcaagg tggttacaac caagacagct atggatcaag cagtgggtac agtcagcagg     1080

cgagtttggg gccaacctca gatgagtttg gccaacagcc tactggcccc acttccttta     1140

ccaatcagat ttaacagagt agcatttgca ttcttctgca gtcgcctcac catcttccat     1200

ttcagtggca gaagaatttt ttaagggttt caatcaatta ttaatgcaga gagtattgaa     1260

tgtaaatcag agctctctag tcttcattaa ggcagcaagt cctgggttgt gaaaaatgat     1320

acttagagat gaggcgacat gaggagatat attattcatc atagatggct aattggagag     1380

taccttgtta tatatacaga tactttcatg gtcattttgt atgtatgtta aagtagtaga     1440

agtattttgt agcttaaagt ctctagtatg taatatgcat aaagtaaatc aaatagcgtt     1500

gagttttctt atgcattttg atgtgaaaga tgttataata atttctagaa gacaatttgg     1560

tgtatcacaa catgcatgtc ttattttttt ttagttttaa gtcctatagg actatgagtc     1620

tctaagttat ttgtttcaga aaattattct ttttttatgt gataaatcat atgatttaag     1680

tgcatgaata agcattttcc cacacaatga acatttgaac tgtgtttatg aaaattttct     1740

ggtttgcacc atgaatttgt caaatggata tttataggaa tatattcact actttgtata     1800

ctttgcaaat ttgtctctct ggctttaccc aagttctgaa tgcattgtaa ttaaaattta     1860

agtttttctt ttcccccatt agtaaacatt tagtgctaca tatgataact gcccaatatt     1920

tattctattt acttagctaa atatttgcat tcttgtaacc ttctatggtg ttttgtggct     1980

cttatcttgt ggaccataaa taacacggcc caataactct ttgtgtttat ggagtgttgt     2040

tttcttagaa taatggagat gcagatatag ataccatagt caaggtaccg ccttgctgaa     2100

gtatttattt ataaagaata ttctgtagaa cctctactac cagctatatt tttaaatcct     2160

gtttatttgt aaagctaata tgctcctcaa tgtaattatt aaaaattctc aagtcacagc     2220

taaacttact aattctgatt ttagtgtagc ccctaaatta aaaatggctt ccatatgcca     2280

ctctgtaccc caaagagagt tctcatgaaa tattctccag aatgtattca ttatcaagaa     2340

aatgtcaatc gtcacttcct cgttttaact cagctgaaac accaggaccc aatagagagg     2400

gcaagctgag catctgtatt tccagataaa agttgttatt gatgtataaa ctcgttgcgt     2460

gattagtgat gttggaagca ttttagcaca aaacagcctt gtgtcttaga tgatatctgt     2520

aaccagtttc tgaatcccgt tggataaaac tgtattgtga tatctatttg atgttaataa     2580

agttattgca taca                                                       2594


<210>  649
<211>  2719
<212>  DNA
<213>  homo sapiens

<400>  649
acttaaggtc ggcgacccga ggccgcggct gccgactggg tcccctgccg ctgtcgccac       60

catggctccg caccgccccg cgcccgcgct gctttgcgcg ctgtccctgg cgctgtgcgc      120

gctgtcgctg cccgtccgcg cggccactgc gtcgcggggg gcgtcccagg cgggggcgcc      180

ccaggggcgg gtgcccgagg cgcggcccaa cagcatggtg gtggaacacc ccgagttcct      240

caaggcaggg aaggagcctg gcctgcagat ctggcgtgtg gagaagttcg atctggtgcc      300

cgtgcccacc aacctttatg gagacttctt cacgggcgac gcctacgtca tcctgaagac      360

agtgcagctg aggaacggaa atctgcagta tgacctccac tactggctgg gcaatgagtg      420

cagccaggat gagagcgggg cggccgccat ctttaccgtg cagctggatg actacctgaa      480

cggccgggcc gtgcagcacc gtgaggtcca gggcttcgag tcggccacct tcctaggcta      540

cttcaagtct ggcctgaagt acaagaaagg aggtgtggca tcaggattca agcacgtggt      600

acccaacgag gtggtggtgc agagactctt ccaggtcaaa gggcggcgtg tggtccgtgc      660

caccgaggta cctgtgtcct gggagagctt caacaatggc gactgcttca tcctggacct      720

gggcaacaac atccaccagt ggtgtggttc caacagcaat cggtatgaaa gactgaaggc      780

cacacaggtg tccaagggca tccgggacaa cgagcggagt ggccgggccc gagtgcacgt      840

gtctgaggag ggcactgagc ccgaggcgat gctccaggtg ctgggcccca agccggctct      900

gcctgcaggt accgaggaca ccgccaagga ggatgcggcc aaccgcaagc tggccaagct      960

ctacaaggtc tccaatggtg cagggaccat gtccgtctcc ctcgtggctg atgagaaccc     1020

cttcgcccag ggggccctga agtcagagga ctgcttcatc ctggaccacg gcaaagatgg     1080

gaaaatcttt gtctggaaag gcaagcaggc aaacacggag gagaggaagg ctgccctcaa     1140

aacagcctct gacttcatca ccaagatgga ctaccccaag cagactcagg tctcggtcct     1200

tcctgagggc ggtgagaccc cactgttcaa gcagttcttc aagaactggc gggacccaga     1260

ccagacagat ggcctgggct tgtcctacct ttccagccat atcgccaacg tggagcgggt     1320

gcccttcgac gccgccaccc tgcacacctc cactgccatg gccgcccagc acggcatgga     1380

tgacgatggc acaggccaga aacagatctg gagaatcgaa ggttccaaca aggtgcccgt     1440

ggaccctgcc acatatggac agttctatgg aggcgacagc tacatcattc tgtacaacta     1500

ccgccatggt ggccgccagg ggcagataat ctataactgg cagggtgccc agtctaccca     1560

ggatgaggtc gctgcatctg ccatcctgac tgctcagctg gatgaggagc tgggaggtac     1620

ccctgtccag agccgtgtgg tccaaggcaa ggagcccgcc cacctcatga gcctgtttgg     1680

tgggaagccc atgatcatct acaagggcgg cacctcccgc gagggcgggc agacagcccc     1740

tgccagcacc cgcctcttcc aggtccgcgc caacagcgct ggagccaccc gggctgttga     1800

ggtattgcct aaggctggtg cactgaactc caacgatgcc tttgttctga aaaccccctc     1860

agccgcctac ctgtgggtgg gtacaggagc cagcgaggca gagaagacgg gggcccagga     1920

gctgctcagg gtgctgcggg cccaacctgt gcaggtggca gaaggcagcg agccagatgg     1980

cttctgggag gccctgggcg ggaaggctgc ctaccgcaca tccccacggc tgaaggacaa     2040

gaagatggat gcccatcctc ctcgcctctt tgcctgctcc aacaagattg gacgttttgt     2100

gatcgaagag gttcctggtg agctcatgca ggaagacctg gcaacggatg acgtcatgct     2160

tctggacacc tgggaccagg tctttgtctg ggttggaaag gattctcaag aagaagaaaa     2220

gacagaagcc ttgacttctg ctaagcggta catcgagacg gacccagcca atcgggatcg     2280

gcggacgccc atcaccgtgg tgaagcaagg ctttgagcct ccctcctttg tgggctggtt     2340

ccttggctgg gatgatgatt actggtctgt ggaccccttg gacagggcca tggctgagct     2400

ggctgcctga ggaggggcag ggcccaccca tgtcaccggt cagtgccttt tggaactgtc     2460

cttccctcaa agaggcctta gagcgagcag agcagctctg ctatgagtgt gtgtgtgtgt     2520

gtgtgttgtt tctttttttt ttttttacag tatccaaaaa tagccctgca aaaattcaga     2580

gtccttgcaa aattgtctaa aatgtcagtg tttgggaaat taaatccaat aaaaacattt     2640

tgaagtgtga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaa                                                  2719


<210>  650
<211>  6798
<212>  DNA
<213>  homo sapiens

<400>  650
gcaagtgaac cggagcaaac gacttccgat ccagtctgcg ctgttgcggc tcccgtttgg       60

gatttgattt gcagcatctt tgagcctcta cgacaaaaaa ccgcgaagca cgcccagccc      120

tcccccggca ccccgaaaag cacccactcc ctcccgggga cacagctggg cgcgtccaca      180

cccccgcagc cccacaccat gttgtgcgga aggacttcca ctccccgcct gtgtcgttga      240

tgtcagaccc caggccagcc tccgggcgct gcagttctcc cggctaatgc tgaggctgcg      300

gctccggctc tagcacaggc accagccgcc gccgcacccg gccccagcgc ccaccgtctg      360

catgtgcccg ccgtagccgt ctgcccagcc cgcagcccgc gctccacgga gcgctggaga      420

ccaccgtggg gggccccttc tgccctcgag agaagcggtc ttggaggtat tgatttaggt      480

ggttggattt tttccgtgga tctatcaatt cacaattcga atttggaaga aagaaggaaa      540

acatgacgtc tccagccaaa ttcaaaaagg ataaggagat catagcagag tacgatactc      600

aggtcaaaga gatccgtgct cagctcacag agcagatgaa atgcctggac cagcagtgtg      660

agcttcgggt gcaactgttg caggacctcc aggacttctt ccgaaagaag gcagagattg      720

agatggacta ctcccgcaac ctggagaagc tggcagaacg cttcctggcc aagacacgca      780

gcaccaagga ccagcaattc aagaaggatc agaatgttct ctctccagtc aactgctgga      840

atctcctctt aaaccaggtg aagcgggaaa gcagggacca taccaccctg agtgacatct      900

acctgaataa tatcattcct cgatttgtac aagtcagcga ggactcagga agactcttta      960

aaaagagtaa agaagtcggc cagcagctcc aagatgattt gatgaaggtc ctgaacgagc     1020

tctactcggt gatgaagaca tatcacatgt acaatgccga cagcatcagt gctcagagca     1080

aactaaagga ggcggagaag caggaggaga agcaaattgg taaatcggta aagcaggagg     1140

accggcagac cccacgctcc cctgactcca cggccaacgt tcgcattgag gagaaacatg     1200

tccggaggag ctcagtgaag aagattgaga agatgaagga gaagcgtcaa gccaagtaca     1260

cggagaataa gctgaaggcc atcaaagccc ggaatgagta cttgctggct ttggaggcaa     1320

ccaatgcatc tgtcttcaag tactacatcc atgacctatc tgaccttatt gattgttgtg     1380

acttaggcta ccatgcaagt ctgaaccggg ctctacgcac cttcctctct gctgagttaa     1440

acctggaaca gtcgaagcat gagggtctgg atgccatcga gaatgcagta gaaaacctgg     1500

atgccaccag tgacaagcag cgcctcatgg agatgtacaa caacgtcttc tgccccccta     1560

tgaagtttga gtttcagccc cacatggggg atatggcttc ccagctctgt gcccagcagc     1620

ctgtccagag tgagctggta cagagatgcc aacaactgca gtctcgctta tccactctaa     1680

agattgaaaa cgaagaggta aagaagacaa tggaggccac cctgcaaacc atccaggaca     1740

ttgtgactgt cgaggacttt gatgtgtctg actgcttcca gtacagcaac tccatggagt     1800

ccgtcaagtc cacggtctct gaaaccttca tgagcaagcc cagcattgct aagaggagag     1860

ccaaccagca agagacagag cagttttatt tcacaaaaat gaaagagtac ctggagggca     1920

ggaacctcat caccaagtta caagccaagc atgaccttct gcagaaaacc ctgggagaaa     1980

gtcagcggac agattgcagt ctagccaggc gcagctcaac tgtgaggaaa caggactcca     2040

gccaggcaat tcctctggtg gtggaaagct gtatccggtt tatcagcaga cacggactac     2100

agcatgaagg aattttccgg gtgtcaggat cccaggtgga agtgaatgac atcaaaaatg     2160

cctttgagag aggagaggac cccctggctg gggaccagaa cgaccatgac atggattcca     2220

tagctggtgt cctgaagctt tacttccggg ggctggaaca ccctctcttc cccaaggaca     2280

tctttcatga cctgatggcc tgcgtcacaa tggacaacct gcaggagaga gctctgcaca     2340

tccggaaagt cctcctagtc ctgcccaaaa ccactctgat tatcatgaga tacctctttg     2400

ccttcctcaa tcatttatca cagttcagtg aagagaacat gatggacccc tacaacctcg     2460

ccatctgctt cgggccctcg ctaatgtcag tgccagaggg ccacgaccag gtgtcctgcc     2520

aagcccacgt gaatgagctg atcaaaacca tcatcatcca gcatgagaac atcttcccaa     2580

gccccaggga gctggagggc cctgtctaca gcagaggagg aagcatggag gattactgtg     2640

atagccctca tggagagact acctcggttg aagactcaac ccaggatgtg accgcagagc     2700

accacacgag cgatgacgaa tgtgagccca tcgaggccat tgccaagttt gactacgtgg     2760

gccggacagc ccgagagcta tcctttaaga agggagcatc cctgctgctt taccagcggg     2820

cttccgacga ctggtgggaa ggccggcaca atggcatcga cggactcatc ccccatcagt     2880

acatcgtggt ccaagacacc gaggacggtg tcgtggagag gtccagcccc aagtctgaga     2940

ttgaggtcat ttctgagcca cctgaagaaa aggtgacagc cagagcgggg gccagctgtc     3000

ccagtggggg tcatgtagcc gatatttatc ttgcaaacat caacaagcaa aggaagcgtc     3060

cagaatctgg gagcatccgg aaaacttttc ggagtgacag ccatgggctg agcagttccc     3120

tgactgactc ctcctcccca ggggtggggg ctagctgccg cccatcctcc cagcccatca     3180

tgagccagag cctccccaaa gaagggccag ataagtgttc catcagtggg cacgggagcc     3240

tcaactccat cagccgccac tcatccctga agaatcggct ggatagtcca cagatccgga     3300

agactgccac agcgggaagg tcaaaaagct tcaataacca tcggcccatg gaccctgagg     3360

tcattgctca ggatattgag gcaacaatga actcggccct gaatgagcta cgggaactag     3420

aacggcagag cagtgtcaaa cacacccctg acgtggttct ggacaccttg gagcccctca     3480

aaacctcccc agtggtggcc cccacgtcag agccctccag ccctctgcac acccagctcc     3540

tcaaggaccc cgagcccgcc ttccagcgca gcgccagtac tgctggggac atcgcctgcg     3600

ccttccggcc tgtcaagtct gtcaagatgg ctgccccggt caaaccacca gccacacggc     3660

ccaagcccac tgtcttcccc aaaacaaatg ccactagccc tggtgtcaac tcatcaactt     3720

ccccacagtc tactgacaag tcttgtactg tctgagggat aataatttaa ttgttctaga     3780

caaggggact atagggactg actgttatta aaatcttcct atttaactag cttggggact     3840

tcagttgaaa attaggttct aagttgttct tgcaggaatt agcctccccg tctcccaaaa     3900

ccttgagaat gaagcccttg gtatcgcctc tcccttccca ctgccctctg cttcccccag     3960

tcgtcgtaat tcagccagct gcagtccgta ccgttcttag gttagccaga gacaggtttt     4020

cattatcagg tcactgtgaa atctggtaag gcagtcctga ggacatgggc tcaagtctca     4080

gtcccctcag accacggtga tgccttgacc agatggttgg ctactgccat ccagctttca     4140

gtggcatctt gttttgggaa ctgattatag agaatcatat atagtccagt cttcatttta     4200

catacacaca catattttac acacacacac attttacaca cacacacaca cacacacaca     4260

cacatatgtt tttctagtct ctggcatgtg tagcctctcc tggtcataga ccagtctctt     4320

tgtaagttat tgtggcagtt cacacagtag ccaccagggg tctctgtttc catcacaaac     4380

tttgttctgt ctgggccaga gaacctagcc tttgaaatct ctccatcata tgaaacataa     4440

cgggatggga caatcccgta acctgtttgg ggttgggggc tttctctctg tgttctttcc     4500

attgatgtga attggtcatt ggtgtttgct cttgcctctc ctccatcccc tagaagtaca     4560

cccccgtctt attaaggagc ttttaaagtt tttctgaatg tatagacatt tctcgggttc     4620

ctacctttgt ctctgatgga ccattttcca tttaagacat tttcctgtat aagacagttt     4680

tatagctggt tccttttagg gtaaagagtc ttaagagagt tttattgtgt ctatggcagg     4740

tttgggaaag gtaagaaatg ggtccttttt cctcctaatg tttttggcac ttaaaacata     4800

aaattcatta tcctattaaa aaattaaatt cagctttgct aatccagaaa ttgttcccaa     4860

atgaaaactt gttttaagtc caccccttag tttccttatt ttacaaggtc tctcttcagg     4920

gaccaacagg ggcttagaga gccttagtta gattaaaggg agaccctacc tcttaaaacc     4980

agttttcatt tatgcaaaca aggacaatta agggaaccct gaccccacag gctctcaagt     5040

cttcccaagg ccagaatcga aagaaaatta aaatttgaat gctgaatatt ctggctctac     5100

tctggccttt tttctggttc ccttccaaaa tgcacaaatc atacccttgt ctgctccaat     5160

tcagtctcca aacctggtgc ctgtgctcct ggccccccta gcatcatgct atcccaggag     5220

tatcaggacc agacacatcc acagccaggc tcatgggtct cagacagcaa cttgagttaa     5280

agctgaaact catccttctt ctctgtgttt tctggtttaa aagctgcact tatattttag     5340

ccttattatt ttctgtagtt ccggagagat ggtgggttgc cattctggta ggaaaatctg     5400

agttttctta tctttgacct agaagagatt ctttttggac caacctgcga aattggtagt     5460

taggtctatg gaaagtggta ggattttttt ttttttaatc ctgtgcaaag gaaaagaggt     5520

gctttgtggg aaatcactaa tgagaaggct aacctgcagc accagagaaa cctttccaag     5580

tgctaggcag gagaactgaa gaactctttc agtgaagtga gtcagcctag aagaggcaac     5640

ccacagtctt gatttttgtt gctgtttcct gacctgttct tgcctgtcac ctgggcctac     5700

acaggtccca agccaacggg gctttcatac ccaaggatct gtttccttgc tgaaaatgaa     5760

accctatctt tcactttaca ttcctttcaa tccaactgat caaaactggt acccacactt     5820

gccctttctc cctctctcca gcacactccc ctctaagaaa gtaaaagcaa agctttctta     5880

atggcaacac tttgggcctg ttctgttgct cctgccttat ttctctttca accctgtaca     5940

tgactcgtgt tcaccatccc cttgatcagt gtccatccgc gctaatttgc atcatgaact     6000

gaacagtgtg tgagtggtca cctactaaac ccagctctgg gggcagagct gtcttcccca     6060

tctctggtgc tcctaacacc tgtgagatgg tcctgtcgag aggactagga accgatagga     6120

ggagagtcct tctcggcaga gctcactgca aacaactgga attgaggttg cacactgtga     6180

tttttacacc gaaaagccaa aaggagctgg ccatccaggg cctagggaga ccagccttcc     6240

tcagctatgc ttgccgaaac cagcatgatg cttcaaagag ccctgctcca cccctcatgg     6300

catggatcct tttcctggtg tggactctga agggtcagtc ttcggggaag agaggtgggg     6360

tggggctact agcatcccaa tttagaaaat agaggagttt gtagccagca gcctgtaaac     6420

tggaaacact ggtctcagcc aacctcctca gggcgccctg gcttctcccc aaggagatga     6480

ggagcggtga tgccagcacc gggatgcgca gagcactgga agggctggtg cagatctact     6540

tcccatgcag aagagaagtc acatcttcca gggaatcgca atgttgtggc gtctgacttg     6600

tatgtcacat ttgtgtaaaa tggtatattc tttaaaatag tgttgataac tggaatattg     6660

tatgtatgct tggagatgct ttgtgtgaac ctaagactgt cactcaacag atgttggatt     6720

ggggaaaatc caaagcacaa cttcaaaata aaatacattt ttaggtttcg atgctgcaaa     6780

aaaaaaaaaa aaaaaaaa                                                   6798


<210>  651
<211>  2303
<212>  DNA
<213>  homo sapiens

<400>  651
gaattcgtcc aaactgagga tcacaagtct ccacattctg agtaggagga tgagggtctg       60

agttaggatt tgggtcctgc agggcttgct aaggaatccc ctgatggcct aggattccac      120

gcagagcaca tctggtgtga gagagctcgc tgcaagggtg aaggctccgc cctatcagat      180

agacaaccag gccaccaaga ggcccagccc tccaaaccct ggatttgcaa catcctcaaa      240

gaacagcaac gggccttgag cagaattgag aaggaaatac ccccacctgc cctcagccgt      300

taagtgggct ttgctattca caagggcctc tgggtgtcct ggcagagagg ggagatggca      360

caggcaccag gtgctagggt gccagggcct cccgagaagg aacaggtgca aagcaggcaa      420

ttagcccaga aggtatccgt ggggcaggca gcctagatct gatgggggaa gccaccagga      480

ttacatcatc tgctgtaaca actgctctga aaagaagata tttttcaacc tgaacttgca      540

gtagctagtg gagaggcagg aaaaaggaaa tgaaaccaga gacagaggga agctgagcga      600

aaatagacct tcccgagaga ggaggaagcc cggagagaga cgcacggtcc cctccccgcc      660

cctaggccgc cgccccctct ctgccctcgg cggcgagcag cgcgccgcga cccgggccga      720

aggtgcgagg ggctccgggc ggccgggcgg gcgcacacca tccccgcggg cggcgcggag      780

ccggcgacag cgcgcgagag ggaccgggcg gtggcggcgg cgggaccggg atggaaggga      840

gcgcggtgac tgtccttgag cgcggagggg cgagctcgcc ggcggagcgc cggagcaagc      900

ggaggcgcag gagcggcggc gacggcggcg gcggcggcgg cgcccgagca cccgaggggg      960

tccgagcccc ggcagccggc cagccccgcg ccacaaaggg agcgcccccg ccgcccggca     1020

ccccgcctcc ctccccaatg tcctcggcca tcgaaaggaa gagcctggac ccttcagagg     1080

aaccagtgga tgaggtgctg cagatccccc catccctgct gacatgcggc ggctgccagc     1140

agaacattgg ggaccgctac ttcctgaagg ccatcgacca gtactggcac gaggactgcc     1200

tgagctgcga cctctgtggc tgccggctgg gtgaggtggg gcggcgcctc tactacaaac     1260

tgggccggaa gctctgccgg agagactatc tcaggctttt tgggcaagac ggtctctgcg     1320

catcctgtga caagcggatt cgtgcctatg agatgacaat gcgggtgaaa gacaaagtgt     1380

atcacctgga atgtttcaaa tgcgccgcct gtcagaagca tttctgtgta ggtgacagat     1440

acctcctcat caactctgac atagtgtgcg aacaggacat ctacgagtgg actaagatca     1500

atgggatgat ataggcccga gtccccgggc atctttgggg aggtgttcac tgaagacgcc     1560

gtctccatgg catcttcgtc ttcactctta ggcactttgg gggtttgagg gtggggtaag     1620

ggatttctta ggggatggta gacctttatt gggtatcaag acatagcatc caagtggcat     1680

aattcagggg ctgacacttc aaggtgacag aaggaccagc ccttgaggga gaacttatgg     1740

ccacagccca tccatagtaa ctgacatgat tagcagaaga aaggaacatt taggggcaag     1800

caggcgctgt gctatcatga tggaatttca tatctacaga tagagagttg ttgtgtacag     1860

acttgttgtg actttgacgc ttgcgaacta gagatgtgca attgatttct tttcttcctg     1920

gctttttaac tcccctgttt caatcactgt cctccacaca agggaaggac agaaaggaga     1980

gtggccattc tttttttctt ggcccccttc ccaaggcctt aagctttgga cccaaggaaa     2040

actgcatgga gacgcatttc ggttgagaat ggaaaccaca acttttaacc aaacaattat     2100

ttaaagcaat gctgatgaat cactgttttt agacaccttc attttgaggg gaggagttcc     2160

acagattgtt tctatacaaa tataaatctt aaaaagttgt tcaactattt tattatccta     2220

gattatatca aagtatttgt cgtgtgtaga aaaaaaaaca gctctgcagg cttaataaaa     2280

atgacagact gaaaaaaaaa aaa                                             2303


<210>  652
<211>  3727
<212>  DNA
<213>  homo sapiens

<400>  652
ttccgcggag gtcctgcctc tccctgcgga cgggcgctga ttggcccgtt tgaaatgcgc       60

caggcgggag ctcacctggg ctcttagcgt cgccgccggc ttcgcagagc accgcgcctt      120

agccgcgaag ttctagttct tgctgccggt cctaacgtcc cgcagtcttc gccagccagc      180

cgtcccgcat gcgcgtttgg gcggcgtgga gcctgctgcc atgaagtcag cgagagctaa      240

gacaccccgg aaacctaccg tgaaaaaagg gtcccaaacg aaccttaaag acccagttgg      300

ggtatactgt agggtgcgcc cactgggctt tcctgatcaa gagtgttgca tagaagtgat      360

caataataca actgttcagc ttcatactcc tgagggctac agactcaacc gaaatggaga      420

ctataaggag actcagtatt catttaaaca agtatttggc actcacacca cccagaagga      480

actctttgat gttgtggcta atcccttggt caatgacctc attcatggca aaaatggtct      540

tctttttaca tatggtgtga cgggaagtgg aaaaactcac acaatgactg gttctccagg      600

ggaaggaggg ctgcttcctc gttgtttgga catgatcttt aacagtatag ggtcatttca      660

agctaaacga tatgttttca aatctaatga taggaatagt atggatatac agtgtgaggt      720

tgatgcctta ttagaacgtc agaaaagaga agctatgccc aatccaaaga cttcttctag      780

caaacgacaa gtagatccag agtttgcaga tatgataact gtacaagaat tctgcaaagc      840

agaagaggtt gatgaagata gtgtctatgg tgtatttgtc tcttatattg aaatatataa      900

taattacata tatgatctat tggaagaggt gccgtttgat cccataaaac ccaaacctcc      960

acaatctaaa ttgcttcgtg aagataagaa ccataacatg tatgttgcag gatgtacaga     1020

agttgaagtg aaatctactg aggaggcttt tgaagttttc tggagaggcc agaaaaagag     1080

acgtattgct aatacccatt tgaatcgtga gtccagccgt tcccatagcg tgttcaacat     1140

taaattagtt caggctccct tggatgcaga tggagacaat gtcttacagg aaaaagaaca     1200

aatcactata agtcagttgt ccttggtaga tcttgctgga agtgaaagaa ctaaccggac     1260

cagagcagaa gggaacagat tacgtgaagc tggtaatatt aatcagtcac taatgacgct     1320

aagaacatgt atggatgtcc taagagagaa ccaaatgtat ggaactaaca agatggttcc     1380

atatcgagat tcaaagttaa cccatctgtt caagaactac tttgatgggg aaggaaaagt     1440

gcggatgatc gtgtgtgtga accccaaggc tgaagattat gaagaaaact tgcaagtcat     1500

gagatttgcg gaagtgactc aagaagttga agtagcaaga cctgtagaca aggcaatatg     1560

tggtttaacg cctgggagga gatacagaaa ccagcctcga ggtccagttg gaaatgaacc     1620

attggttact gacgtggttt tgcagagttt tccacctttg ccatcatgcg aaattttgga     1680

tatcaacgat gagcagacac ttccaaggct gattgaagcc ttagagaaac gacataactt     1740

acgacaaatg atgattgatg agtttaacaa acaatctaat gcttttaaag ctttgttaca     1800

agaatttgac aatgctgttt taagtaaaga aaaccacatg caagggaaac taaatgaaaa     1860

ggagaagatg atctcaggac agaaattgga aatagaacga ctggaaaaga aaaacaaaac     1920

tttagaatat aagattgaga ttttagagaa aacaactact atctatgagg aagataaacg     1980

caatttgcaa caggaacttg aaactcagaa ccagaaactt cagcgacagt tttctgacaa     2040

acgcagatta gaagccaggt tgcaaggcat ggtgacagaa acgacaatga agtgggagaa     2100

agaatgtgag cgtagagtgg cagccaaaca gctggagatg cagaataaac tctgggttaa     2160

agatgaaaag ctgaaacaac tgaaggctat tgttaccgaa cctaaaactg agaagccaga     2220

gagaccctct cgggagcgag atcgagaaaa agttactcaa agatctgttt ctccatcacc     2280

tgtgcctctt tctagtaact atattgctca gatttccaac ggccagcaac tcatgagcca     2340

gccacagcta cataggcgct ctaactcttg cagcagcatt tctgtagctt cctgtatttc     2400

ggaatgggag cagaaaattc ctacgtacaa cacacctctc aaagtcacat ctattgcaag     2460

gcgtaggcag caggagccag gacaaagcaa aacttgtatc gtgtcagaca gaaggcgagg     2520

gatgtactgg actgaaggca gggaggtggt tcctacattc agaaatgaga tagaaataga     2580

agaggatcat tgcggcaggt tactctttca acctgatcag aacgcaccac caattcgtct     2640

ccgacacaga cgatcacgct ctgcaggaga cagatgggta gatcataagc ccgcctctaa     2700

catgcaaact gaaacagtca tgcagccaca tgtccctcat gccatcacag tatctgttgc     2760

aaatgaaaag gcactagcta agtgtgagaa gtacatgctg acccaccagg aactagcctc     2820

cgatggggag attgaaacta aactaattaa gggtgatatt tataaaacaa ggggtggtgg     2880

acaatctgtt cagtttactg atattgagac tttaaagcaa gaatcaccaa atggtagtcg     2940

aaaacgaaga tcttccacag tagcacctgc ccaaccagat ggtgcagagt ctgaatggac     3000

cgatgtagaa acaaggtgtt ctgtggctgt ggagatgaga gcaggatccc agctgggacc     3060

tggatatcag catcacgcac aacccaagcg caaaaagcca tgaactgaca gtcccagtac     3120

tgaaagaaca ttttcatttg tgtggatgat ttctcgaaag ccatgccaga agcagtcttc     3180

caggtcatct tgtagaactc cagctttgtt gaaaatcacg gacctcagct acatcataca     3240

ctgacccaga gcaaagcttt ccctatggtt ccaaagacaa ctagtattca acaaaccttg     3300

tatagtatat gttttgccat atttaatatt aatagcagag gaagactcct tttttcatca     3360

ctgtatgaat tttttataat gtttttttaa aatatatttc atgtatactt ataaactaat     3420

tcacacaagt gtttgtctta gatgattaag gaagactata tctagatcat gtctgatttt     3480

ttattgtgac ttctccagcc ctggtctgaa tttcttaagg ttttataaac aaatgctgct     3540

atttattagc tgcaagaatg cactttagaa ctatttgaca attcagactt tcaaaataaa     3600

gatgtaaatg actggccaat aataaccatt ttaggaaggt gttttgaatt ctgtatgtat     3660

atattcactt tctgacattt agatatgcca aaagaattaa aatcaaaagc actaagaaat     3720

acaaaaa                                                               3727


<210>  653
<211>  6133
<212>  DNA
<213>  homo sapiens

<400>  653
actactccct ctgcagtctc gcctgccgac ttccttctgc gcgcctcgta aaaccgggga       60

agttcaatca ttccgcagcg agccgcggcg gccgcactgg gcatgctcag tctccgggct      120

ccgctcggca ggcgagaggc gtcctccggc tctgggctcc ggtcggtggg tgcctcggct      180

cggctttccc cggcgctggc tgggctcagc ggcccctgag cccaagcgac acacgccccg      240

cggtccccga tccggcccct gggagagccg cgccgttctg gaacccggga gcccccaact      300

tcgcgccaag ttcggagccg ccttctgagg gagacatgaa aaagatgagc aggaatgttt      360

tgctacaaat ggaggaggag gaggacgacg acgatgggga tatcgtgttg gaaaaccttg      420

gacagacaat tgtccccgat ttgggatcac tggaaagtca gcatgatttt cgaaccccgg      480

agtttgaaga atttaatgga aaacctgact ccctcttttt taatgatggc cagcgaagaa      540

ttgactttgt tctagtatat gaggatgaaa gcagaaaaga gaccaataaa aagggtacaa      600

atgaaaaaca aaggaggaaa agacaagcat acgaatctaa ccttatctgt catggcctgc      660

agttagaagc aacaagatca gtattggatg acaagcttgt atttgtaaaa gtacacgcac      720

catgggaggt gttatgtacg tatgctgaga taatgcacat caaattgcct ctgaaaccca      780

atgatctgaa aaaccggtcc tcagcctttg gtacactcaa ctggtttacc aaagtcctca      840

gtgtagacga aagcatcatc aagccagagc aagagttttt cactgcccca tttgagaaga      900

accggatgaa tgatttttac atagttgata gagatgcttt cttcaatcca gccaccagaa      960

gccgcattgt ttacttcatc ctctctcggg tcaagtatca agtgataaac aatgttagca     1020

agtttgggat caacagactt gtaaactctg ggatctacaa ggcagctttc ccactccatg     1080

attgcaaatt ccgccgtcag tcagaggatc ccagctgccc taatgaacgg taccttctgt     1140

acagagaatg ggctcatcct cgaagcatat acaaaaagca gcccttggat cttatcagga     1200

aatactatgg agagaagatt ggaatctact ttgcttggct gggctattac actcagatgc     1260

ttctcctggc cgcagttgta ggagtggctt gctttctcta tggatatctt aatcaagata     1320

actgtacatg gagcaaagaa gtttgtcatc ctgatattgg tggcaagatc ataatgtgtc     1380

ctcagtgtga taggctttgt ccattctgga aactcaatat tacttgcgag tcctcaaaga     1440

aattgtgcat cttcgacagt tttggaaccc tggtctttgc agtatttatg ggagtatggg     1500

ttaccttgtt tttggagttt tggaagcgac gccaggcaga acttgagtat gaatgggata     1560

ctgttgagtt acagcaggaa gaacaagccc gaccagaata cgaagcacga tgtactcacg     1620

tagtgataaa tgagattact caggaagaag aacgcattcc ctttactgcc tggggaaaat     1680

gtatacggat aaccctctgt gccagtgctg tctttttctg gatcctattg atcatcgctt     1740

cagttattgg gatcattgtc tataggctct cggtgttcat tgtattttct gcaaaacttc     1800

ccaagaacat taatggaaca gacccaatcc agaaatacct gactccacag acagccacgt     1860

ccatcacggc ctccatcatc agctttataa ttatcatgat tctgaacacc atatatgaaa     1920

aagtggcaat tatgattact aacttcgaac tcccaaggac ccagactgat tatgagaaca     1980

gcctcaccat gaagatgttc ttattccagt ttgtcaacta ctactcttca tgcttctaca     2040

tagcattctt taagggcaaa tttgtaggct atccaggaga cccagtttat tggttgggaa     2100

aatacagaaa tgaagagtgt gacccaggtg gctgtcttct tgaactgaca actcagctga     2160

caataatcat gggaggaaaa gcaatctgga ataacataca agaagtatta ttgccctgga     2220

tcatgaatct aattgggcga tttcacagag tttctggatc agaaaagata accccacgat     2280

gggaacagga ctaccatctg cagcctatgg gcaaactggg attattttat gaatatcttg     2340

aaatgattat tcagtttggg ttcgtcacct tatttgtggc ctcttttcca ctggcccctc     2400

tgttggctct cgtgaacaat atattggaaa taagagtgga cgcatggaaa ctgaccaccc     2460

agtttagacg cctggtacca gagaaagccc aagacattgg agcatggcag cccatcatgc     2520

aaggaatagc aattctggct gtggtgacca atgccatgat catagctttc acgtcggaca     2580

tgatcccccg cctagtgtac tactggtcct tctccgtccc tccctacggg gaccacactt     2640

cctacaccat ggaagggtac atcaacaaca ctctctccat cttcaaagtc gcagacttca     2700

aaaacaaaag caagggaaac ccgtactctg acctgggtaa ccataccaca tgcaggtatc     2760

gtgatttccg atacccacct ggacaccccc aggagtataa acacaacatc tactattggc     2820

atgtgattgc agccaagctg gcttttatca ttgtcatgga gcacgtcatc tactctgtga     2880

aatttttcat ttcatatgca attcccgatg tatcaaaacg cacaaagagc aagatccaga     2940

gagaaaaata cctaacccaa aagcttcttc atgagaatca cctcaaagat atgacgaaaa     3000

atatgggggt gatagctgag cggatgatag aagcagtaga taacaattta cggccaaaat     3060

cagaataaga gctttatgtt ctgagaagca ctttaaggaa tttagctttg tcaaaatata     3120

ttaggaatca ctaatgagaa tgtgtaagtt aaatcacttt ggcaaatatg agtctcaact     3180

attgccattt cctcatgtat tatttttcag tttcagctag cgatgcagaa actggaaaat     3240

gtaaaactta gatcatgaag ggcataaaac ttatcacccg gaaaacctca atgttacctt     3300

tttctgataa attggaattt tacagaaaaa gtccctcagt gtgcttaaaa accacccctt     3360

ctaaagtaga atggattctt ttttttctgt ttgattattt tcatttctgt ctattctcag     3420

gcgcatgatc tcctttattt ttaagccatg tttcatttct tcacttggct agatctgttc     3480

cagggtcatc ttttccttac agtaccatca ttatagattt aatttaatag ctttcatgtg     3540

attaaaaata gctaactaga ctcaaggatt cacaatattt aggtgtattt tcaatacctc     3600

cagaaaggaa acctcagtta atcagaggaa atagtttcag tcttcatttg agcatgtctt     3660

tccatctcaa aaaaatactc ttagtaggtt ggagtgaaga tagcaaggtt ttgaagcata     3720

tttgtcctaa tccacagtga cactttttat cttccaggag cactcctagg aggttccgtg     3780

cctaatcaat gttgactgct ttgcagatct caagggaata aaatgacaaa agcagggaaa     3840

gttacagatt caaacagcat tttaactcat gttgatctgg ataattaatc ttttctaaag     3900

atgtgtagtt tcttggaaaa cagtgatatc acatgattaa aattacattt ttatcaacat     3960

aattgtctgg aaaagataag cccctcaatt ttctaccagt tgacttttat tcattagata     4020

cagaaggtgc agtattacac atcaccagct gcctttgtga atggctcact acacagccat     4080

tggggtacaa ctgtgtgcat gggcagaaac agcaagtgcc ctcattgtgg tcattgggtg     4140

gggagtgcct tttgtcaagg agtctgcagg aattggctta tttctgtatg ccaaagtgat     4200

caacacacca aagtctctgc cataaagaat gtggcttcct tgcatcctcc atcctgttac     4260

tctgggccca gtaatttgat gtaactgtct gattgtacta gagacaggag tatacccagc     4320

ttattcataa tcaagtaaag agactcagat tagatttgat tttttagcct cctctagagc     4380

caatcaggca gttaagagta ataaaggaaa agggtttggt cacaaaccct accattatct     4440

ggagattact tcctgctgca ctcctgtctt gccatgcacg tcttgccccc tcacttttgc     4500

tcagcctagc agtctacttc actttattgc cttgtaagtg tcaggcctcc tgggcgctct     4560

ggaaaagaca gggagccagg ccctctcacc cctactggta acaggtcatt gctgggtgca     4620

caagagggag gtgatttgca tcatggtcat gctgcatggg cttcactggg atgctgttaa     4680

acaccagagg agccaaccta tcagaatccc agcagcaaag gaaaactcag attttagagg     4740

ctttttacaa taaagtagcg taactctagg tcatgattga tttcaaatgc ctgccatgaa     4800

tgatttgtaa gtaattatgt aggatccatc aaagcagtat tgtaggcttt tgaattgtcc     4860

cagtggatcc gggaccccat ttcactgtct ctcttgatcg tgttaatgat gcaatcagag     4920

ttcaagacag gccccatgaa gtctgactgc actgggatgg agaaatgaat ttcttcccac     4980

tgaaggaaac tctttctcat tcgcagccaa gacgggagtg ccactgttcc tctcttcact     5040

cctgagatac tgcttctgga agcgggtgtc acttcctctc tagtacctct tctcttctct     5100

gaagtgtgtg actatctcct agtgtttaaa tttggcagtt actcgccatg tatgtcagca     5160

tagaaaagga aatgttttta ccttatctcc tgtatgtatg atagaactta aaagaaatgt     5220

gcatttgttt tcatagcccc agcagagaaa atcctcttca tagattaaat gtgctgctgt     5280

ggacaggagg ggaaaaaaaa ccctctacat attgaaaggc accaaatgta atatctgaca     5340

ctgttaagat gcccaaaaga gcaaagttgt agtggagatg cagggtcatt tccccatgcc     5400

atccacagtg tttgttagtg agtccacggc tgacttgcag tgataaagaa aagcatggag     5460

ctgtgtctgc agacaatggt ggctgcatct gtaagtggct tcagaggcag cagccctggg     5520

gaaattgatg ggtgtggcag tggacctgtg aagagggaga atctagcctt cagcctgtcc     5580

agtgttaacc actagagaaa ctgagcttta tatccttttt taatgcctgt gaattttagc     5640

atattgaaac attagagcaa atactcaggg gatttttcat taaacatccc tcagataatt     5700

tagctatata tcattagaaa gggaaagcta tcatttttat tttaaaacta aacaaggcca     5760

tcttataaac tgtcaccaaa gtcttccctt ttttattgca tgtgtgcctt gaatttcata     5820

aaacattaat tcacaatggg ggtcagaatg tactcttgtt gaaacacttc ttgtaccatt     5880

ttatgttcat attatgtttg agagggtaaa aatgtatgag cagcttaact gaagtagaac     5940

tattcatgat gcttttcaca cattgtggca taagatgtaa agtttgtaat taatgttaat     6000

ttctgtgcat tttaatattc ttttataatt attaatgtta atttctgtgc attttaatat     6060

tcttttataa ttatgagcat tttaataaat tcatttttac aaacaataaa aaaaaaaaaa     6120

aaaaaaaaaa aaa                                                        6133


<210>  654
<211>  3046
<212>  DNA
<213>  homo sapiens

<400>  654
agaaagagag caaagagaaa agagagagag aggtgctctg gctccggggc tcttctccca       60

aacgggtcga ggtcccagct gaggctctcc caggacaagt ccctcagccc cagtgaacgt      120

caccgtcagg cacctcaagg ccaactctgc agtggtgagc tgggatgttc tggaggatga      180

ggttgtcatc ggatttgcca tctcccagca gaagaaggat gtgcggatgc tgcgcttcat      240

ccaggaggtg aacaccacca cccgctcatg tgccctctgg gacctggagg aggatacgga      300

gtacatagtc cacgtgcagg ccatctccat tcagggccag agcccagcca gcgagcctgt      360

gctcttcaag accccgcgtg aggctgagaa gatggcctcc aagaacaaag atgaggtaac      420

catgaaagag atggggagga accaacagct gcggacaggc gaggtgctga tcatcgtcgt      480

ggtcctgttc atgtgggcag gtgtcattgc cctcttctgc cgccagtatg acatcatcaa      540

ggacaatgaa cccaataaca acaaggaaaa aaccaagagt gcatcagaaa ccagcacacc      600

agagcaccag ggcggggggc ttctccgcag caaggtgagg gcaagacctg ggcctgggtg      660

ggccaccctg tgcctcatgc tctggtaatc cctggactgc agagggggtc agctcgggga      720

ctggcatggc gacagctggg cagagccaga cttggctgct gcctgtgtga cacagggaca      780

ctgcaagttg attttggatc ctctcctttt gcagggtgcc aggggccagt ggtgatttga      840

agaaaaaaaa aaaaaagcag tgagtgggga gggcagaatt cttggttggc gcgggacaat      900

aggagtgggg tgtctggccc attcctgctc ctgctgtgcc ttgtgacctt gggcaggtgc      960

tttaccgctg taccttcatt tcctcttctg taaaacagat atgaaaacct tttcagtgct     1020

tgccctcagc agctaagaag acagacagta gagaatgtga gaggatctca tggttctgat     1080

gatgattatc caacaaacat ctggccctct ctacatctct tccctccatc tccttgtacc     1140

ctctggctta ctgtcctctc tctggcgcac tttcctgaag cctcttatta actcccatct     1200

ccagaagcac ctcaacaatg tcagtggctg aggctgcact cagagggatg actgctgggg     1260

gtagactggg tgccaggggc catgggccca ggacccagtc ttggccattc agttgagtga     1320

ggctgaaggc tgggtttgaa aaggcaaaaa gacaagacat ccaggcaggg cttctctttt     1380

ctttccacaa gggacaagag cttggcttat ttaggctaca gccctgctgc tgctcccttc     1440

cttcttctgt cctgtttcca gccttgcaag aaggctattc acaattaggc ctggctgctt     1500

ctctcatttt tttcctccca gtttccaaac aagccctcag tgaacatcat tgaagcgtga     1560

ctgcctgtct gcagggagaa ggattccatt tttcttctca gctggtcccc aggcccacgg     1620

gcacagggag agggacaact gcagcagtgg ggaggaggca cagctagctg cacagttctc     1680

tcttctcctt gtcctagtca gatgaaggag gctgcactac aaacccaaat tctgcaaaaa     1740

aataaaaata agccacaaaa ctaaaaggcc tggccccatt ctggaaaagg caaagctgca     1800

tgagacacag ccttctgcct cctcgcctct cctggactgg cttcctcttt gagaaaatgc     1860

acaaagccct gggagatgac aagcacaagg actgactcaa gctgtgtctt tcagaccaag     1920

gaacatcaga gaagctgtgg ggctgcctgc caggcaggat catggctgcc atcaagcctt     1980

ttctggatcc agccatcaag gacatgtttg tggtgtgatg cacacttttg caagcgtgta     2040

agatgttacc tggtttgtct cttttggaaa acaaaaatca gaaggctgca ttctagaggg     2100

cagagaaatt cccccgaaga ctgagctggt tgcctgcatc ctctatcttc tttgaccctt     2160

atgactgaaa gatcatcagt ttggaaggta ctggtccaat ttatttagga agtatctctt     2220

ggagtttcag aaatgctagc ttggacaact gaaaagtcac atcacagctg gcattctggg     2280

ggctaccaaa acaccccttc tggagtagaa gctgctggaa ggcaggcctg agccattcac     2340

cacggacagg aagagcagct ctggctatca ccactggcct ctggggtctt catatcttgc     2400

catctcatcc agggttccat gaaagttacc cagggtcctc atgtccttcc ttagagcctg     2460

agtggtgtga ggtgacaggt ctctctctcc actgcccctt tctggtttaa aaaaatggtg     2520

cttgatgagg gaaggtagac tcttccctag gactgacgag ttacggctgc cagatgcctg     2580

catgggaaga ggtggacatc tgcatcttcc attggtggtc aaggatgggt gtgggagaac     2640

cacacctagt gcaagcctgg tactcagtaa atatttgttg aaatgaatga taagagcatt     2700

ggtccccaag ccagagagcc agaagccatc acccaatgac cgccccttcc ttccggtcta     2760

caagagctct caaggctggg tctgccacca ctctgctttg cccaagtgtg acagcactgg     2820

ggaggagaga caggataaag ggcagatgtc agcaatacta agggcttcct catgggaggg     2880

catgaggctc cactcattgt cttgtgactt ccatccctgc tgaatggggc tgcaaggcca     2940

aggctcctta ggggagaggt ccttacctct gatccactta gagcaataac cactttttaa     3000

atgtaaaata aaaagacaaa tgaaaaggca aaaaaaaaaa aaaaaa                    3046


<210>  655
<211>  2748
<212>  DNA
<213>  homo sapiens

<400>  655
gcggccgccg ggcgccggag ccgcgtcccc ctgcgccgcc ccgggcctgc cggccggagg       60

agccaccata caccccgggt cgccgagcgc ctggccgccc cgcgcccgcg ccgcgctccg      120

cctgtggctg ggctgcgtct gcttcgcgct ggtgcaggcg gacagtccct cagccccagt      180

gaacgtcacc gtcaggcacc tcaaggccaa ctctgcagtg gtgagctggg atgttctgga      240

ggatgaggtt gtcatcggat ttgccatctc ccagcagaag aaggatgtgc ggatgctgcg      300

cttcatccag gaggtgaaca ccaccacccg ctcatgtgcc ctctgggacc tggaggagga      360

tacggagtac atagtccacg tgcaggccat ctccattcag ggccagagcc cagccagcga      420

gcctgtgctc ttcaagaccc cgcgtgaggc tgagaagatg gcctccaaga acaaagatga      480

ggtaaccatg aaagagatgg ggaggaacca acagctgcgg acaggcgagg tgctgatcat      540

cgtcgtggtc ctgttcatgt gggcaggtgt cattgccctc ttctgccgcc agtatgacat      600

catcaaggac aatgaaccca ataacaacaa ggaaaaaacc aagagtgcat cagaaaccag      660

cacaccagag caccagggcg gggggcttct ccgcagcaag atatgaaaac cttttcagtg      720

cttgccctca gcagctaaga agacagacag tagagaatgt gagaggatct catggttctg      780

atgatgatta tccaacaaac atctggccct ctctacatct cttccctcca tctccttgta      840

ccctctggct tactgtcctc tctctggcgc actttcctga agcctcttat taactcccat      900

ctccagaagc acctcaacaa tgtcagtggc tgaggctgca ctcagaggga tgactgctgg      960

gggtagactg ggtgccaggg gccatgggcc caggacccag tcttggccat tcagttgagt     1020

gaggctgaag gctgggtttg aaaaggcaaa aagacaagac atccaggcag ggcttctctt     1080

ttctttccac aagggacaag agcttggctt atttaggcta cagccctgct gctgctccct     1140

tccttcttct gtcctgtttc cagccttgca agaaggctat tcacaattag gcctggctgc     1200

ttctctcatt tttttcctcc cagtttccaa acaagccctc agtgaacatc attgaagcgt     1260

gactgcctgt ctgcagggag aaggattcca tttttcttct cagctggtcc ccaggcccac     1320

gggcacaggg agagggacaa ctgcagcagt ggggaggagg cacagctagc tgcacagttc     1380

tctcttctcc ttgtcctagt cagatgaagg aggctgcact acaaacccaa attctgcaaa     1440

aaaataaaaa taagccacaa aactaaaagg cctggcccca ttctggaaaa ggcaaagctg     1500

catgagacac agccttctgc ctcctcgcct ctcctggact ggcttcctct ttgagaaaat     1560

gcacaaagcc ctgggagatg acaagcacaa ggactgactc aagctgtgtc tttcagacca     1620

aggaacatca gagaagctgt ggggctgcct gccaggcagg atcatggctg ccatcaagcc     1680

ttttctggat ccagccatca aggacatgtt tgtggtgtga tgcacacttt tgcaagcgtg     1740

taagatgtta cctggtttgt ctcttttgga aaacaaaaat cagaaggctg cattctagag     1800

ggcagagaaa ttcccccgaa gactgagctg gttgcctgca tcctctatct tctttgaccc     1860

ttatgactga aagatcatca gtttggaagg tactggtcca atttatttag gaagtatctc     1920

ttggagtttc agaaatgcta gcttggacaa ctgaaaagtc acatcacagc tggcattctg     1980

ggggctacca aaacacccct tctggagtag aagctgctgg aaggcaggcc tgagccattc     2040

accacggaca ggaagagcag ctctggctat caccactggc ctctggggtc ttcatatctt     2100

gccatctcat ccagggttcc atgaaagtta cccagggtcc tcatgtcctt ccttagagcc     2160

tgagtggtgt gaggtgacag gtctctctct ccactgcccc tttctggttt aaaaaaatgg     2220

tgcttgatga gggaaggtag actcttccct aggactgacg agttacggct gccagatgcc     2280

tgcatgggaa gaggtggaca tctgcatctt ccattggtgg tcaaggatgg gtgtgggaga     2340

accacaccta gtgcaagcct ggtactcagt aaatatttgt tgaaatgaat gataagagca     2400

ttggtcccca agccagagag ccagaagcca tcacccaatg accgcccctt ccttccggtc     2460

tacaagagct ctcaaggctg ggtctgccac cactctgctt tgcccaagtg tgacagcact     2520

ggggaggaga gacaggataa agggcagatg tcagcaatac taagggcttc ctcatgggag     2580

ggcatgaggc tccactcatt gtcttgtgac ttccatccct gctgaatggg gctgcaaggc     2640

caaggctcct taggggagag gtccttacct ctgatccact tagagcaata accacttttt     2700

aaatgtaaaa taaaaagaca aatgaaaagg caaaaaaaaa aaaaaaaa                  2748


<210>  656
<211>  2158
<212>  DNA
<213>  homo sapiens

<400>  656
attcataaaa cgcttgttat aaaagcagtg gctgcggcgc ctcgtactcc aaccgcatct       60

gcagcgagca tctgagaagc caagactgag ccggcggccg cggcgcagcg aacgagcagt      120

gaccgtgctc ctacccagct ctgctccaca gcgcccacct gtctccgccc ctcggcccct      180

cgcccggctt tgcctaaccg ccacgatgat gttctcgggc ttcaacgcag actacgaggc      240

gtcatcctcc cgctgcagca gcgcgtcccc ggccggggat agcctctctt actaccactc      300

acccgcagac tccttctcca gcatgggctc gcctgtcaac gcgcaggact tctgcacgga      360

cctggccgtc tccagtgcca acttcattcc cacggtcact gccatctcga ccagtccgga      420

cctgcagtgg ctggtgcagc ccgccctcgt ctcctccgtg gccccatcgc agaccagagc      480

ccctcaccct ttcggagtcc ccgccccctc cgctggggct tactccaggg ctggcgttgt      540

gaagaccatg acaggaggcc gagcgcagag cattggcagg aggggcaagg tggaacagtt      600

atctccagaa gaagaagaga aaaggagaat ccgaagggaa aggaataaga tggctgcagc      660

caaatgccgc aaccggagga gggagctgac tgatacactc caagcggaga cagaccaact      720

agaagatgag aagtctgctt tgcagaccga gattgccaac ctgctgaagg agaaggaaaa      780

actagagttc atcctggcag ctcaccgacc tgcctgcaag atccctgatg acctgggctt      840

cccagaagag atgtctgtgg cttcccttga tctgactggg ggcctgccag aggttgccac      900

cccggagtct gaggaggcct tcaccctgcc tctcctcaat gaccctgagc ccaagccctc      960

agtggaacct gtcaagagca tcagcagcat ggagctgaag accgagccct ttgatgactt     1020

cctgttccca gcatcatcca ggcccagtgg ctctgagaca gcccgctccg tgccagacat     1080

ggacctatct gggtccttct atgcagcaga ctgggagcct ctgcacagtg gctccctggg     1140

gatggggccc atggccacag agctggagcc cctgtgcact ccggtggtca cctgtactcc     1200

cagctgcact gcttacacgt cttccttcgt cttcacctac cccgaggctg actccttccc     1260

cagctgtgca gctgcccacc gcaagggcag cagcagcaat gagccttcct ctgactcgct     1320

cagctcaccc acgctgctgg ccctgtgagg gggcagggaa ggggaggcag ccggcaccca     1380

caagtgccac tgcccgagct ggtgcattac agagaggaga aacacatctt ccctagaggg     1440

ttcctgtaga cctagggagg accttatctg tgcgtgaaac acaccaggct gtgggcctca     1500

aggacttgaa agcatccatg tgtggactca agtccttacc tcttccggag atgtagcaaa     1560

acgcatggag tgtgtattgt tcccagtgac acttcagaga gctggtagtt agtagcatgt     1620

tgagccaggc ctgggtctgt gtctcttttc tctttctcct tagtcttctc atagcattaa     1680

ctaatctatt gggttcatta ttggaattaa cctggtgctg gatattttca aattgtatct     1740

agtgcagctg attttaacaa taactactgt gttcctggca atagtgtgtt ctgattagaa     1800

atgaccaata ttatactaag aaaagatacg actttatttt ctggtagata gaaataaata     1860

gctatatcca tgtactgtag tttttcttca acatcaatgt tcattgtaat gttactgatc     1920

atgcattgtt gaggtggtct gaatgttctg acattaacag ttttccatga aaacgtttta     1980

ttgtgttttt aatttattta ttaagatgga ttctcagata tttatatttt tattttattt     2040

ttttctacct tgaggtcttt tgacatgtgg aaagtgaatt tgaatgaaaa atttaagcat     2100

tgtttgctta ttgttccaag acattgtcaa taaaagcatt taagttgaat gcgaccaa       2158


<210>  657
<211>  2158
<212>  DNA
<213>  homo sapiens

<400>  657
attcataaaa cgcttgttat aaaagcagtg gctgcggcgc ctcgtactcc aaccgcatct       60

gcagcgagca tctgagaagc caagactgag ccggcggccg cggcgcagcg aacgagcagt      120

gaccgtgctc ctacccagct ctgctccaca gcgcccacct gtctccgccc ctcggcccct      180

cgcccggctt tgcctaaccg ccacgatgat gttctcgggc ttcaacgcag actacgaggc      240

gtcatcctcc cgctgcagca gcgcgtcccc ggccggggat agcctctctt actaccactc      300

acccgcagac tccttctcca gcatgggctc gcctgtcaac gcgcaggact tctgcacgga      360

cctggccgtc tccagtgcca acttcattcc cacggtcact gccatctcga ccagtccgga      420

cctgcagtgg ctggtgcagc ccgccctcgt ctcctccgtg gccccatcgc agaccagagc      480

ccctcaccct ttcggagtcc ccgccccctc cgctggggct tactccaggg ctggcgttgt      540

gaagaccatg acaggaggcc gagcgcagag cattggcagg aggggcaagg tggaacagtt      600

atctccagaa gaagaagaga aaaggagaat ccgaagggaa aggaataaga tggctgcagc      660

caaatgccgc aaccggagga gggagctgac tgatacactc caagcggaga cagaccaact      720

agaagatgag aagtctgctt tgcagaccga gattgccaac ctgctgaagg agaaggaaaa      780

actagagttc atcctggcag ctcaccgacc tgcctgcaag atccctgatg acctgggctt      840

cccagaagag atgtctgtgg cttcccttga tctgactggg ggcctgccag aggttgccac      900

cccggagtct gaggaggcct tcaccctgcc tctcctcaat gaccctgagc ccaagccctc      960

agtggaacct gtcaagagca tcagcagcat ggagctgaag accgagccct ttgatgactt     1020

cctgttccca gcatcatcca ggcccagtgg ctctgagaca gcccgctccg tgccagacat     1080

ggacctatct gggtccttct atgcagcaga ctgggagcct ctgcacagtg gctccctggg     1140

gatggggccc atggccacag agctggagcc cctgtgcact ccggtggtca cctgtactcc     1200

cagctgcact gcttacacgt cttccttcgt cttcacctac cccgaggctg actccttccc     1260

cagctgtgca gctgcccacc gcaagggcag cagcagcaat gagccttcct ctgactcgct     1320

cagctcaccc acgctgctgg ccctgtgagg gggcagggaa ggggaggcag ccggcaccca     1380

caagtgccac tgcccgagct ggtgcattac agagaggaga aacacatctt ccctagaggg     1440

ttcctgtaga cctagggagg accttatctg tgcgtgaaac acaccaggct gtgggcctca     1500

aggacttgaa agcatccatg tgtggactca agtccttacc tcttccggag atgtagcaaa     1560

acgcatggag tgtgtattgt tcccagtgac acttcagaga gctggtagtt agtagcatgt     1620

tgagccaggc ctgggtctgt gtctcttttc tctttctcct tagtcttctc atagcattaa     1680

ctaatctatt gggttcatta ttggaattaa cctggtgctg gatattttca aattgtatct     1740

agtgcagctg attttaacaa taactactgt gttcctggca atagtgtgtt ctgattagaa     1800

atgaccaata ttatactaag aaaagatacg actttatttt ctggtagata gaaataaata     1860

gctatatcca tgtactgtag tttttcttca acatcaatgt tcattgtaat gttactgatc     1920

atgcattgtt gaggtggtct gaatgttctg acattaacag ttttccatga aaacgtttta     1980

ttgtgttttt aatttattta ttaagatgga ttctcagata tttatatttt tattttattt     2040

ttttctacct tgaggtcttt tgacatgtgg aaagtgaatt tgaatgaaaa atttaagcat     2100

tgtttgctta ttgttccaag acattgtcaa taaaagcatt taagttgaat gcgaccaa       2158


<210>  658
<211>  5980
<212>  DNA
<213>  homo sapiens

<400>  658
ttggggcaga ggaggcttgt aggaataggg gaagagttca taagcagagc tgaaacaaca       60

ccaaacatgg aaatgttaca aggtggagaa attgtgctta ctgaaactct tctcagaaat      120

attgctgttt gtggatgata gaaatcttca gagttgtcac ttaaggtaga ggtaggaggg      180

taagaagcgt caaggactca ccgaattgtc cattccccct tttgttctgc tgtggaatgt      240

tttgtgctgc tgtgttggaa aaccttggac agacaattgt ccccgatttg ggatcactgg      300

aaagtcagca tgattttcga accccggagt ttgaagaatt taatggaaaa cctgactccc      360

tcttttttaa tgatggccag cgaagaattg actttgttct agtatatgag gatgaaagca      420

gaaaagagac caataaaaag ggtacaaatg aaaaacaaag gaggaaaaga caagcatacg      480

aatctaacct tatctgtcat ggcctgcagt tagaagcaac aagatcagta ttggatgaca      540

agcttgtatt tgtaaaagta cacgcaccat gggaggtgtt atgtacgtat gctgagataa      600

tgcacatcaa attgcctctg aaacccaatg atctgaaaaa ccggtcctca gcctttggta      660

cactcaactg gtttaccaaa gtcctcagtg tagacgaaag catcatcaag ccagagcaag      720

agtttttcac tgccccattt gagaagaacc ggatgaatga tttttacata gttgatagag      780

atgctttctt caatccagcc accagaagcc gcattgttta cttcatcctc tctcgggtca      840

agtatcaagt gataaacaat gttagcaagt ttgggatcaa cagacttgta aactctggga      900

tctacaaggc agctttccca ctccatgatt gcaaattccg ccgtcagtca gaggatccca      960

gctgccctaa tgaacggtac cttctgtaca gagaatgggc tcatcctcga agcatataca     1020

aaaagcagcc cttggatctt atcaggaaat actatggaga gaagattgga atctactttg     1080

cttggctggg ctattacact cagatgcttc tcctggccgc agttgtagga gtggcttgct     1140

ttctctatgg atatcttaat caagataact gtacatggag caaagaagtt tgtcatcctg     1200

atattggtgg caagatcata atgtgtcctc agtgtgatag gctttgtcca ttctggaaac     1260

tcaatattac ttgcgagtcc tcaaagaaat tgtgcatctt cgacagtttt ggaaccctgg     1320

tctttgcagt atttatggga gtatgggtta ccttgttttt ggagttttgg aagcgacgcc     1380

aggcagaact tgagtatgaa tgggatactg ttgagttaca gcaggaagaa caagcccgac     1440

cagaatacga agcacgatgt actcacgtag tgataaatga gattactcag gaagaagaac     1500

gcattccctt tactgcctgg ggaaaatgta tacggataac cctctgtgcc agtgctgtct     1560

ttttctggat cctattgatc atcgcttcag ttattgggat cattgtctat aggctctcgg     1620

tgttcattgt attttctgca aaacttccca agaacattaa tggaacagac ccaatccaga     1680

aatacctgac tccacagaca gccacgtcca tcacggcctc catcatcagc tttataatta     1740

tcatgattct gaacaccata tatgaaaaag tggcaattat gattactaac ttcgaactcc     1800

caaggaccca gactgattat gagaacagcc tcaccatgaa gatgttctta ttccagtttg     1860

tcaactacta ctcttcatgc ttctacatag cattctttaa gggcaaattt gtaggctatc     1920

caggagaccc agtttattgg ttgggaaaat acagaaatga agagtgtgac ccaggtggct     1980

gtcttcttga actgacaact cagctgacaa taatcatggg aggaaaagca atctggaata     2040

acatacaaga agtattattg ccctggatca tgaatctaat tgggcgattt cacagagttt     2100

ctggatcaga aaagataacc ccacgatggg aacaggacta ccatctgcag cctatgggca     2160

aactgggatt attttatgaa tatcttgaaa tgattattca gtttgggttc gtcaccttat     2220

ttgtggcctc ttttccactg gcccctctgt tggctctcgt gaacaatata ttggaaataa     2280

gagtggacgc atggaaactg accacccagt ttagacgcct ggtaccagag aaagcccaag     2340

acattggagc atggcagccc atcatgcaag gaatagcaat tctggctgtg gtgaccaatg     2400

ccatgatcat agctttcacg tcggacatga tcccccgcct agtgtactac tggtccttct     2460

ccgtccctcc ctacggggac cacacttcct acaccatgga agggtacatc aacaacactc     2520

tctccatctt caaagtcgca gacttcaaaa acaaaagcaa gggaaacccg tactctgacc     2580

tgggtaacca taccacatgc aggtatcgtg atttccgata cccacctgga cacccccagg     2640

agtataaaca caacatctac tattggcatg tgattgcagc caagctggct tttatcattg     2700

tcatggagca cgtcatctac tctgtgaaat ttttcatttc atatgcaatt cccgatgtat     2760

caaaacgcac aaagagcaag atccagagag aaaaatacct aacccaaaag cttcttcatg     2820

agaatcacct caaagatatg acgaaaaata tgggggtgat agctgagcgg atgatagaag     2880

cagtagataa caatttacgg ccaaaatcag aataagagct ttatgttctg agaagcactt     2940

taaggaattt agctttgtca aaatatatta ggaatcacta atgagaatgt gtaagttaaa     3000

tcactttggc aaatatgagt ctcaactatt gccatttcct catgtattat ttttcagttt     3060

cagctagcga tgcagaaact ggaaaatgta aaacttagat catgaagggc ataaaactta     3120

tcacccggaa aacctcaatg ttaccttttt ctgataaatt ggaattttac agaaaaagtc     3180

cctcagtgtg cttaaaaacc accccttcta aagtagaatg gattcttttt tttctgtttg     3240

attattttca tttctgtcta ttctcaggcg catgatctcc tttattttta agccatgttt     3300

catttcttca cttggctaga tctgttccag ggtcatcttt tccttacagt accatcatta     3360

tagatttaat ttaatagctt tcatgtgatt aaaaatagct aactagactc aaggattcac     3420

aatatttagg tgtattttca atacctccag aaaggaaacc tcagttaatc agaggaaata     3480

gtttcagtct tcatttgagc atgtctttcc atctcaaaaa aatactctta gtaggttgga     3540

gtgaagatag caaggttttg aagcatattt gtcctaatcc acagtgacac tttttatctt     3600

ccaggagcac tcctaggagg ttccgtgcct aatcaatgtt gactgctttg cagatctcaa     3660

gggaataaaa tgacaaaagc agggaaagtt acagattcaa acagcatttt aactcatgtt     3720

gatctggata attaatcttt tctaaagatg tgtagtttct tggaaaacag tgatatcaca     3780

tgattaaaat tacattttta tcaacataat tgtctggaaa agataagccc ctcaattttc     3840

taccagttga cttttattca ttagatacag aaggtgcagt attacacatc accagctgcc     3900

tttgtgaatg gctcactaca cagccattgg ggtacaactg tgtgcatggg cagaaacagc     3960

aagtgccctc attgtggtca ttgggtgggg agtgcctttt gtcaaggagt ctgcaggaat     4020

tggcttattt ctgtatgcca aagtgatcaa cacaccaaag tctctgccat aaagaatgtg     4080

gcttccttgc atcctccatc ctgttactct gggcccagta atttgatgta actgtctgat     4140

tgtactagag acaggagtat acccagctta ttcataatca agtaaagaga ctcagattag     4200

atttgatttt ttagcctcct ctagagccaa tcaggcagtt aagagtaata aaggaaaagg     4260

gtttggtcac aaaccctacc attatctgga gattacttcc tgctgcactc ctgtcttgcc     4320

atgcacgtct tgccccctca cttttgctca gcctagcagt ctacttcact ttattgcctt     4380

gtaagtgtca ggcctcctgg gcgctctgga aaagacaggg agccaggccc tctcacccct     4440

actggtaaca ggtcattgct gggtgcacaa gagggaggtg atttgcatca tggtcatgct     4500

gcatgggctt cactgggatg ctgttaaaca ccagaggagc caacctatca gaatcccagc     4560

agcaaaggaa aactcagatt ttagaggctt tttacaataa agtagcgtaa ctctaggtca     4620

tgattgattt caaatgcctg ccatgaatga tttgtaagta attatgtagg atccatcaaa     4680

gcagtattgt aggcttttga attgtcccag tggatccggg accccatttc actgtctctc     4740

ttgatcgtgt taatgatgca atcagagttc aagacaggcc ccatgaagtc tgactgcact     4800

gggatggaga aatgaatttc ttcccactga aggaaactct ttctcattcg cagccaagac     4860

gggagtgcca ctgttcctct cttcactcct gagatactgc ttctggaagc gggtgtcact     4920

tcctctctag tacctcttct cttctctgaa gtgtgtgact atctcctagt gtttaaattt     4980

ggcagttact cgccatgtat gtcagcatag aaaaggaaat gtttttacct tatctcctgt     5040

atgtatgata gaacttaaaa gaaatgtgca tttgttttca tagccccagc agagaaaatc     5100

ctcttcatag attaaatgtg ctgctgtgga caggagggga aaaaaaaccc tctacatatt     5160

gaaaggcacc aaatgtaata tctgacactg ttaagatgcc caaaagagca aagttgtagt     5220

ggagatgcag ggtcatttcc ccatgccatc cacagtgttt gttagtgagt ccacggctga     5280

cttgcagtga taaagaaaag catggagctg tgtctgcaga caatggtggc tgcatctgta     5340

agtggcttca gaggcagcag ccctggggaa attgatgggt gtggcagtgg acctgtgaag     5400

agggagaatc tagccttcag cctgtccagt gttaaccact agagaaactg agctttatat     5460

ccttttttaa tgcctgtgaa ttttagcata ttgaaacatt agagcaaata ctcaggggat     5520

ttttcattaa acatccctca gataatttag ctatatatca ttagaaaggg aaagctatca     5580

tttttatttt aaaactaaac aaggccatct tataaactgt caccaaagtc ttcccttttt     5640

tattgcatgt gtgccttgaa tttcataaaa cattaattca caatgggggt cagaatgtac     5700

tcttgttgaa acacttcttg taccatttta tgttcatatt atgtttgaga gggtaaaaat     5760

gtatgagcag cttaactgaa gtagaactat tcatgatgct tttcacacat tgtggcataa     5820

gatgtaaagt ttgtaattaa tgttaatttc tgtgcatttt aatattcttt tataattatt     5880

aatgttaatt tctgtgcatt ttaatattct tttataatta tgagcatttt aataaattca     5940

tttttacaaa caataaaaaa aaaaaaaaaa aaaaaaaaaa                           5980


<210>  659
<211>  5809
<212>  DNA
<213>  homo sapiens

<400>  659
aaaggggggg aacctagagt cggtgggggg gaagcgatgt ttgcccgtca gtcgagtccg       60

gagtgaggag ctcggtcgcc gaagcggagg gagactcttg agcttcatct tgccgccgcc      120

acggccaccg cctggacctt tgcccggagg gagctgcaga gggtccatcg ccgccgtcct      180

ctggagggca gcgcgattgg gggcccggac ctccagtccg ggggggattt ttcgtcgtcc      240

ccctcccccc aaccagggag cccgagcggc cgccaaacaa aggtaccagt cgccgccgcg      300

ggaggaggag gagccggagc ctctgcctca gcagccgctg gacccgccgc ccttcttccc      360

catctctccc ccgggcctgc tggttttggg ggggagaagg agagagggga ctctggacgt      420

gccagggtca gatctcgcct ccgaggaagg tgcagctgaa cctggtgttt tagaggatac      480

cttggtccca gagtcatcat gaaggccctt gatgagcctc cctatttgac agtgggcact      540

gatgtgagtg ctaaatacag aggagccttt tgtgaagcca agatcaagac agcaaaaaga      600

cttgtcaaag tcaaggtgac atttagacat gattcttcaa cagtggaagt tcaggatgac      660

cacataaagg gcccactaaa ggtaggagct attgtggaag tgaagaatct tgatggtgca      720

tatcaggaag ctgttatcaa taaactaaca gatgcgagtt ggtacactgt agtttttgat      780

gacggagatg agaagacact gagacgatct tcactgtgcc tgaaaggaga gaggcatttt      840

gctgaaagtg aaacattaga ccagctccca ctcaccaacc ctgagcattt tggcactcca      900

gtcataggaa agaaaacaaa tagaggaaga agatctaatc atataccaga ggaagagtct      960

tcatcatcct ccagtgatga agatgaggat gataggaaac agattgatga gctactaggc     1020

aaagttgtat gtgtagatta cattagtttg gataaaaaga aagcactgtg gtttcctgca     1080

ttggtggttt gtcctgattg tagtgatgag attgctgtaa aaaaggacaa tattcttgtt     1140

cgatctttca aagatggaaa atttacttca gttccaagaa aagatgtcca tgaaattact     1200

agtgacactg caccaaagcc tgatgctgtt ttaaagcaag cctttgaaca ggcacttgaa     1260

tttcacaaaa gtagaactat tcctgctaac tggaagactg aattgaaaga agatagctct     1320

agcagtgaag cagaggaaga agaggaggag gaagatgatg aaaaagaaaa ggaggataat     1380

agcagtgaag aagaagaaga aatagaacca tttccagaag aaagggagaa ctttcttcag     1440

caattgtaca aatttatgga agatagaggt acacctatta acaaacgacc tgtacttgga     1500

tatcgaaatt tgaatctctt taagttattc agacttgtac acaaacttgg aggatttgat     1560

aatattgaaa gtggagctgt ttggaaacaa gtctaccaag atcttggaat ccctgtctta     1620

aattcagctg caggatacaa tgttaaatgt gcttataaaa aatacttata tggttttgag     1680

gagtactgta gatcagccaa cattgaattt cagatggcat tgccagagaa agttgttaac     1740

aagcaatgta aggagtgtga aaatgtaaaa gaaataaaag ttaaggagga aaatgaaaca     1800

gagatcaaag aaataaagat ggaggaggag aggaatataa taccaagaga agaaaagcct     1860

attgaggatg aaattgaaag aaaagaaaat attaagccct ctctgggaag taaaaagaat     1920

ttattagaat ctatacctac acattctgat caggaaaaag aagttaacat taaaaaacca     1980

gaagacaatg aaaatctgga tgacaaagat gatgacacaa ctagggtaga tgaatccctc     2040

aacataaagg tagaagctga ggaagaaaaa gcaaaatctg gatacgatga atggattaaa     2100

gcagataaaa tagtaagacc tgctgataaa aatgtgccaa agataaaaca tcggaagaaa     2160

ataaagaata aattagacaa agaaaaagac aaagatgaaa aatactctcc aaaaaactgt     2220

aaacttcggc gcttgtccaa accaccattt cagacaaatc catctcctga aatggtatcc     2280

aaactggatc tcactgatgc caaaaactct gatactgctc atattaagtc catagaaatt     2340

acttcgatcc ttaatggact tcaagcttct gaaagttctg ctgaagacag tgagcaggaa     2400

gatgagagag gtgctcaaga catggataat aatggcaaag aggaatctaa gattgatcat     2460

ttgaccaaca acagaaatga tcttatttca aaggaggaac agaacagttc atctttgcta     2520

gaagaaaaca aagttcatgc agatttggta atatccaaac cagtgtcaaa atctccagaa     2580

agattaagga aagatataga agtattatcc gaagatactg attatgaaga agatgaagtc     2640

acaaaaaaga gaaaggatgt caagaaggac acaacagata aatcttcaaa accacaaata     2700

aaacgtggta aaagaaggta ttgcaataca gaagagtgtc taaaaactgg atcacctggc     2760

aaaaaggaag agaaggccaa gaacaaagaa tcactttgca tggaaaacag tagcaacagc     2820

tcttcagatg aagatgaaga agaaacaaaa gcaaagatga caccaactaa gaaatacaat     2880

ggtttggagg aaaaaagaaa atctctacgg acaactggtt tctattcagg attttcagaa     2940

gtggcagaaa aaaggattaa acttttaaat aactctgatg aaagacttca aaacagcagg     3000

gccaaagatc gaaaagatgt ctggtcaagt attcagggac agtggcctaa aaaaacgctg     3060

aaagagcttt tttcagactc tgatactgag gctgcagctt ccccaccgca tcctgcccca     3120

gaggaggggg tggcagagga gtcactgcag actgtggctg aagaggagag ttgttcaccc     3180

agtgtagaac tagaaaaacc acctccagtc aatgtcgata gtaaacccat tgaagaaaaa     3240

acagtagagg tcaatgacag aaaagcagaa tttccaagta gtggcagtaa ttcagtgcta     3300

aatacccctc ctactacacc tgaatcgcct tcatcagtca ctgtaacaga aggcagccgg     3360

cagcagtctt ctgtaacagt atcagaacca ctggctccaa accaagaaga ggttcgaagt     3420

atcaagagtg aaactgatag cacaattgag gtggatagtg ttgctgggga gctccaagac     3480

ctccagtctg aagggaatag ctcgccagca ggttttgatg ccagtgtgag ctcaagcagt     3540

agtaatcagc cagaaccaga acatcctgaa aaagcctgta caggtcagaa aagagtgaaa     3600

gatgctcagg gaggaggaag ttcatcaaaa aagcagaaaa gaagccataa agcaacagtg     3660

gtaaacaaca aaaagaaggg aaaaggcaca aatagtagtg atagtgaaga actttcagct     3720

ggtgaaagta taactaagag tcagccagtc aaatcagttt ccactggaat gaagtctcat     3780

agtaccaaat ctcccgcaag gacgcagtct ccaggaaaat gtggaaagaa tggtgataag     3840

gatcctgatc tcaaggaacc cagtaatcga ttacccaaag tttacaaatg gagttttcag     3900

atgtcggacc tggaaaatat gacaagtgcc gaacgcatca caattcttca agaaaaactt     3960

caagaaatca gaaaacatta tctgtcatta aaatctgaag tagcttccat tgatcggagg     4020

agaaagcgtt taaagaagaa agagagagaa agtgctgcta catcctcatc ctcctcttca     4080

ccttcatcca gttccataac agctgctgtt atgttaactt tagctgaacc gtcaatgtcc     4140

agcgcatcac aaaatggaat gtcagttgag tgcaggtgac agcaggactt gctaaagcac     4200

tttgcactta atggctgttg agggccactt tttttttata ctgcacagtg gcacaaaaaa     4260

atatcagaca agcactattt tatatttaaa aattgtttct tgacaagctg acttggcact     4320

taagtgcact tttttatgaa gaaaaagtac aatgaactgc ttttcctcaa gcaataattg     4380

tttccaactt gtctgggaat tgtgtgtctg gtaactggaa ggccttccac tgtggcaaat     4440

ggaggctttt cactgcctgt agagacaata cagtaagcat agttaagggg tgggtcagaa     4500

catgttaaga taacttactg tatatgtatt cccttgtatt ttgttaaagc tggaacattt     4560

gatatttttc catttattta tgaaaaaata tgaacctatt ttcatttgta caaggtaatt     4620

gttttttaaa gcaagtcacc ttagggtggc tttaattgta taagtcaagc acatgtaata     4680

aattcaaaac ctgcagttaa caggatatta gacatcaatc ctggtaacca aatattaaag     4740

attctcttta aaaaagactg aacatgttta caggtttgaa ttaggctaaa aggtcttgca     4800

gtggcttttc atggcccttc aaattggaat ggaactactg tactttgcca tttttctata     4860

aatcagtatt tttttttaat tttgatatac attgtgtgaa aaaagaaaat ggctaataaa     4920

ctgtattaaa tcttaaacaa tgtataaaga ttgtacttag ccagttcaaa gtgtatattt     4980

attcataatg aattataaca gttatatttt tgtgttttct tgtaaatgtt tcttttccct     5040

taaatacaga taattcattt gtattgctta ttttattatg agctacaaca aaaggacttc     5100

aggaacaagt aatgtattag tatggttcaa gattgttgat aggaactgtc tcaaaaggat     5160

ggtggttatt ttaaatataa atagctaatg ggggtggtag gcctataaaa ttaaatgcct     5220

tgtataaaat ccaaaatgaa tgcaaaattg ttttcacttg tattgacttt atgttgtatg     5280

attccaatct ctgttctgtt tggcacttgt atttaattct tcacctttgt aagacatttg     5340

tatattgtgg atgtgttcat tcaagctatt taatatctgg cactgttaat acacagtact     5400

ttattgtaca gactgtttta ctgttttaat tgtagttctg tgtacttttt ttggatgggg     5460

ctggcatgtt ttctttgttt cctggcaata cgacgtggga atttcaatgc gttttgttgt     5520

agatgctaac gtgtcagaat cctttacatt caacttttct aagaaaagca ttttcagtct     5580

tgtagtgtgt gcttacagta actaattttg ttgaaaatgg tttcaagtta ttcaaatttg     5640

tacaggactg taaagatttg ttgacagcaa aatgttgaag aaaaaagctt atagaataaa     5700

agctataaag tatatattag gatctgcaaa caatgaagaa ttatgtaata tattgtacaa     5760

atgtaagcaa aggctctgaa ataaaatgcc atagtttgtg aatccttga                 5809


<210>  660
<211>  13509
<212>  DNA
<213>  homo sapiens

<400>  660
ggggcatttc cgggtccggg ccgagcgggc gcacgcgcgg gagcgggact cggcggcatg       60

gcgggctccg gagccggtgt gcgttgctcc ctgctgcggc tgcaggagac cttgtccgct      120

gcggaccgct gcggtgctgc cctggccggt catcaactga tccgcggcct ggggcaggaa      180

tgcgtcctga gcagcagccc cgcggtgctg gcattacaga catctttagt tttttccaga      240

gatttcggtt tgcttgtatt tgtccggaag tcactcaaca gtattgaatt tcgtgaatgt      300

agagaagaaa tcctaaagtt tttatgtatt ttcttagaaa aaatgggcca gaagatcgca      360

ccttactctg ttgaaattaa gaacacttgt accagtgttt atacaaaaga tagagctgct      420

aaatgtaaaa ttccagccct ggaccttctt attaagttac ttcagacttt tagaagttct      480

agactcatgg atgaatttaa aattggagaa ttatttagta aattctatgg agaacttgca      540

ttgaaaaaaa aaataccaga tacagtttta gaaaaagtat atgagctcct aggattattg      600

ggtgaagttc atcctagtga gatgataaat aatgcagaaa acctgttccg cgcttttctg      660

ggtgaactta agacccagat gacatcagca gtaagagagc ccaaactacc tgttctggca      720

ggatgtctga aggggttgtc ctcacttctg tgcaacttca ctaagtccat ggaagaagat      780

ccccagactt caagggagat ttttaatttt gtactaaagg caattcgtcc tcagattgat      840

ctgaagagat atgctgtgcc ctcagctggc ttgcgcctat ttgccctgca tgcatctcag      900

tttagcacct gccttctgga caactacgtg tctctatttg aagtcttgtt aaagtggtgt      960

gcccacacaa atgtagaatt gaaaaaagct gcactttcag ccctggaatc ctttctgaaa     1020

caggtttcta atatggtggc gaaaaatgca gaaatgcata aaaataaact gcagtacttt     1080

atggagcagt tttatggaat catcagaaat gtggattcga acaacaagga gttatctatt     1140

gctatccgtg gatatggact ttttgcagga ccgtgcaagg ttataaacgc aaaagatgtt     1200

gacttcatgt acgttgagct cattcagcgc tgcaagcaga tgttcctcac ccagacagac     1260

actggtgacg accgtgttta tcagatgcca agcttcctcc agtctgttgc aagcgtcttg     1320

ctgtaccttg acacagttcc tgaggtgtat actccagttc tggagcacct cgtggtgatg     1380

cagatagaca gtttcccaca gtacagtcca aaaatgcagc tggtgtgttg cagagccata     1440

gtgaaggtgt tcctagcttt ggcagcaaaa gggccagttc tcaggaattg cattagtact     1500

gtggtgcatc agggtttaat cagaatatgt tctaaaccag tggtccttcc aaagggccct     1560

gagtctgaat ctgaagacca ccgtgcttca ggggaagtca gaactggcaa atggaaggtg     1620

cccacataca aagactacgt ggatctcttc agacatctcc tgagctctga ccagatgatg     1680

gattctattt tagcagatga agcatttttc tctgtgaatt cctccagtga aagtctgaat     1740

catttacttt atgatgaatt tgtaaaatcc gttttgaaga ttgttgagaa attggatctt     1800

acacttgaaa tacagactgt tggggaacaa gagaatggag atgaggcgcc tggtgtttgg     1860

atgatcccaa cttcagatcc agcggctaac ttgcatccag ctaaacctaa agatttttcg     1920

gctttcatta acctggtgga attttgcaga gagattctcc ctgagaaaca agcagaattt     1980

tttgaaccat gggtgtactc attttcatat gaattaattt tgcaatctac aaggttgccc     2040

ctcatcagtg gtttctacaa attgctttct attacagtaa gaaatgccaa gaaaataaaa     2100

tatttcgagg gagttagtcc aaagagtctg aaacactctc ctgaagaccc agaaaagtat     2160

tcttgctttg ctttatttgt gaaatttggc aaagaggtgg cagttaaaat gaagcagtac     2220

aaagatgaac ttttggcctc ttgtttgacc tttcttctgt ccttgccaca caacatcatt     2280

gaactcgatg ttagagccta cgttcctgca ctgcagatgg ctttcaaact gggcctgagc     2340

tataccccct tggcagaagt aggcctgaat gctctagaag aatggtcaat ttatattgac     2400

agacatgtaa tgcagcctta ttacaaagac attctcccct gcctggatgg atacctgaag     2460

acttcagcct tgtcagatga gaccaagaat aactgggaag tgtcagctct ttctcgggct     2520

gcccagaaag gatttaataa agtggtgtta aagcatctga agaagacaaa gaacctttca     2580

tcaaacgaag caatatcctt agaagaaata agaattagag tagtacaaat gcttggatct     2640

ctaggaggac aaataaacaa aaatcttctg acagtcacgt cctcagatga gatgatgaag     2700

agctatgtgg cctgggacag agagaagcgg ctgagctttg cagtgccctt tagagagatg     2760

aaacctgtca ttttcctgga tgtgttcctg cctcgagtca cagaattagc gctcacagcc     2820

agtgacagac aaactaaagt tgcagcctgt gaacttttac atagcatggt tatgtttatg     2880

ttgggcaaag ccacgcagat gccagaaggg ggacagggag ccccacccat gtaccagctc     2940

tataagcgga cgtttcctgt gctgcttcga cttgcgtgtg atgttgatca ggtgacaagg     3000

caactgtatg agccactagt tatgcagctg attcactggt tcactaacaa caagaaattt     3060

gaaagtcagg atactgttgc cttactagaa gctatattgg atggaattgt ggaccctgtt     3120

gacagtactt taagagattt ttgtggtcgg tgtattcgag aattccttaa atggtccatt     3180

aagcaaataa caccacagca gcaggagaag agtccagtaa acaccaaatc gcttttcaag     3240

cgactttata gccttgcgct tcaccccaat gctttcaaga ggctgggagc atcacttgcc     3300

tttaataata tctacaggga attcagggaa gaagagtctc tggtggaaca gtttgtgttt     3360

gaagccttgg tgatatacat ggagagtctg gccttagcac atgcagatga gaagtcctta     3420

ggtacaattc aacagtgttg tgatgccatt gatcacctat gccgcatcat tgaaaagaag     3480

catgtttctt taaataaagc aaagaaacga cgtttgccgc gaggatttcc accttccgca     3540

tcattgtgtt tattggatct ggtcaagtgg cttttagctc attgtgggag gccccagaca     3600

gaatgtcgac acaaatccat tgaactcttt tataaattcg ttcctttatt gccaggcaac     3660

agatccccta atttgtggct gaaagatgtt ctcaaggaag aaggtgtctc ttttctcatc     3720

aacacctttg aggggggtgg ctgtggccag ccctcgggca tcctggccca gcccaccctc     3780

ttgtaccttc gggggccatt cagcctgcag gccacgctat gctggctgga cctgctcctg     3840

gccgcgttgg agtgctacaa cacgttcatt ggcgagagaa ctgtaggagc gctccaggtc     3900

ctaggtactg aagcccagtc ttcacttttg aaagcagtgg ctttcttctt agaaagcatt     3960

gccatgcatg acattatagc agcagaaaag tgctttggca ctggggcagc aggtaacaga     4020

acaagcccac aagagggaga aaggtacaac tacagcaaat gcaccgttgt ggtccggatt     4080

atggagttta ccacgactct gctaaacacc tccccggaag gatggaagct cctgaagaag     4140

gacttgtgta atacacacct gatgagagtc ctggtgcaga cgctgtgtga gcccgcaagc     4200

ataggtttca acatcggaga cgtccaggtt atggctcatc ttcctgatgt ttgtgtgaat     4260

ctgatgaaag ctctaaagat gtccccatac aaagatatcc tagagaccca tctgagagag     4320

aaaataacag cacagagcat tgaggagctt tgtgccgtca acttgtatgg ccctgacgcg     4380

caagtggaca ggagcaggct ggctgctgtt gtgtctgcct gtaaacagct tcacagagct     4440

gggcttctgc ataatatatt accgtctcag tccacagatt tgcatcattc tgttggcaca     4500

gaacttcttt ccctggttta taaaggcatt gcccctggag atgagagaca gtgtctgcct     4560

tctctagacc tcagttgtaa gcagctggcc agcggacttc tggagttagc ctttgctttt     4620

ggaggactgt gtgagcgcct tgtgagtctt ctcctgaacc cagcggtgct gtccacggcg     4680

tccttgggca gctcacaggg cagcgtcatc cacttctccc atggggagta tttctatagc     4740

ttgttctcag aaacgatcaa cacggaatta ttgaaaaatc tggatcttgc tgtattggag     4800

ctcatgcagt cttcagtgga taataccaaa atggtgagtg ccgttttgaa cggcatgtta     4860

gaccagagct tcagggagcg agcaaaccag aaacaccaag gactgaaact tgcgactaca     4920

attctgcaac actggaagaa gtgtgattca tggtgggcca aagattcccc tctcgaaact     4980

aaaatggcag tgctggcctt actggcaaaa attttacaga ttgattcatc tgtatctttt     5040

aatacaagtc atggttcatt ccctgaagtc tttacaacat atattagtct acttgctgac     5100

acaaagctgg atctacattt aaagggccaa gctgtcactc ttcttccatt cttcaccagc     5160

ctcactggag gcagtctgga ggaacttaga cgtgttctgg agcagctcat cgttgctcac     5220

ttccccatgc agtccaggga atttcctcca ggaactccgc ggttcaataa ttatgtggac     5280

tgcatgaaaa agtttctaga tgcattggaa ttatctcaaa gccctatgtt gttggaattg     5340

atgacagaag ttctttgtcg ggaacagcag catgtcatgg aagaattatt tcaatccagt     5400

ttcaggagga ttgccagaag gggttcatgt gtcacacaag taggccttct ggaaagcgtg     5460

tatgaaatgt tcaggaagga tgacccccgc ctaagtttca cacgccagtc ctttgtggac     5520

cgctccctcc tcactctgct gtggcactgt agcctggatg ctttgagaga attcttcagc     5580

acaattgtgg tggatgccat tgatgtgttg aagtccaggt ttacaaagct aaatgaatct     5640

acctttgata ctcaaatcac caagaagatg ggctactata agattctaga cgtgatgtat     5700

tctcgccttc ccaaagatga tgttcatgct aaggaatcaa aaattaatca agttttccat     5760

ggctcgtgta ttacagaagg aaatgaactt acaaagacat tgattaaatt gtgctacgat     5820

gcatttacag agaacatggc aggagagaat cagctgctgg agaggagaag actttaccat     5880

tgtgcagcat acaactgcgc catatctgtc atctgctgtg tcttcaatga gttaaaattt     5940

taccaaggtt ttctgtttag tgaaaaacca gaaaagaact tgcttatttt tgaaaatctg     6000

atcgacctga agcgccgcta taattttcct gtagaagttg aggttcctat ggaaagaaag     6060

aaaaagtaca ttgaaattag gaaagaagcc agagaagcag caaatgggga ttcagatggt     6120

ccttcctata tgtcttccct gtcatatttg gcagacagta ccctgagtga ggaaatgagt     6180

caatttgatt tctcaaccgg agttcagagc tattcataca gctcccaaga ccctagacct     6240

gccactggtc gttttcggag acgggagcag cgggacccca cggtgcatga tgatgtgctg     6300

gagctggaga tggacgagct caatcggcat gagtgcatgg cgcccctgac ggccctggtc     6360

aagcacatgc acagaagcct gggcccgcct caaggagaag aggattcagt gccaagagat     6420

cttccttctt ggatgaaatt cctccatggc aaactgggaa atccaatagt accattaaat     6480

atccgtctct tcttagccaa gcttgttatt aatacagaag aggtctttcg cccttacgcg     6540

aagcactggc ttagcccctt gctgcagctg gctgcttctg aaaacaatgg aggagaagga     6600

attcactaca tggtggttga gatagtggcc actattcttt catggacagg cttggccact     6660

ccaacagggg tccctaaaga tgaagtgtta gcaaatcgat tgcttaattt cctaatgaaa     6720

catgtctttc atccaaaaag agctgtgttt agacacaacc ttgaaattat aaagaccctt     6780

gtcgagtgct ggaaggattg tttatccatc ccttataggt taatatttga aaagttttcc     6840

ggtaaagatc ctaattctaa agacaactca gtagggattc aattgctagg catcgtgatg     6900

gccaatgacc tgcctcccta tgacccacag tgtggcatcc agagtagcga atacttccag     6960

gctttggtga ataatatgtc ctttgtaaga tataaagaag tgtatgccgc tgcagcagaa     7020

gttctaggac ttatacttcg atatgttatg gagagaaaaa acatactgga ggagtctctg     7080

tgtgaactgg ttgcgaaaca attgaagcaa catcagaata ctatggagga caagtttatt     7140

gtgtgcttga acaaagtgac caagagcttc cctcctcttg cagacaggtt catgaatgct     7200

gtgttctttc tgctgccaaa atttcatgga gtgttgaaaa cactctgtct ggaggtggta     7260

ctttgtcgtg tggagggaat gacagagctg tacttccagt taaagagcaa ggacttcgtt     7320

caagtcatga gacatagaga tgatgaaaga caaaaagtat gtttggacat aatttataag     7380

atgatgccaa agttaaaacc agtagaactc cgagaacttc tgaaccccgt tgtggaattc     7440

gtttcccatc cttctacaac atgtagggaa caaatgtata atattctcat gtggattcat     7500

gataattaca gagatccaga aagtgagaca gataatgact cccaggaaat atttaagttg     7560

gcaaaagatg tgctgattca aggattgatc gatgagaacc ctggacttca attaattatt     7620

cgaaatttct ggagccatga aactaggtta ccttcaaata ccttggaccg gttgctggca     7680

ctaaattcct tatattctcc taagatagaa gtgcactttt taagtttagc aacaaatttt     7740

ctgctcgaaa tgaccagcat gagcccagat tatccaaacc ccatgttcga gcatcctctg     7800

tcagaatgcg aatttcagga atataccatt gattctgatt ggcgtttccg aagtactgtt     7860

ctcactccga tgtttgtgga gacccaggcc tcccagggca ctctccagac ccgtacccag     7920

gaagggtccc tctcagctcg ctggccagtg gcagggcaga taagggccac ccagcagcag     7980

catgacttca cactgacaca gactgcagat ggaagaagct catttgattg gctgaccggg     8040

agcagcactg acccgctggt cgaccacacc agtccctcat ctgactcctt gctgtttgcc     8100

cacaagagga gtgaaaggtt acagagagca cccttgaagt cagtggggcc tgattttggg     8160

aaaaaaaggc tgggccttcc aggggacgag gtggataaca aagtgaaagg tgcggccggc     8220

cggacggacc tactacgact gcgcagacgg tttatgaggg accaggagaa gctcagtttg     8280

atgtatgcca gaaaaggcgt tgctgagcaa aaacgagaga aggaaatcaa gagtgagtta     8340

aaaatgaagc aggatgccca ggtcgttctg tacagaagct accggcacgg agaccttcct     8400

gacattcaga tcaagcacag cagcctcatc accccgttac aggccgtggc ccagagggac     8460

ccaataattg caaaacagct ctttagcagc ttgttttctg gaattttgaa agagatggat     8520

aaatttaaga cactgtctga aaaaaacaac atcactcaaa agttgcttca agacttcaat     8580

cgttttctta ataccacctt ctctttcttt ccaccctttg tctcttgtat tcaggacatt     8640

agctgtcagc acgcagccct gctgagcctc gacccagcgg ctgttagcgc tggttgcctg     8700

gccagcctac agcagcccgt gggcatccgc ctgctagagg aggctctgct ccgcctgctg     8760

cctgctgagc tgcctgccaa gcgagtccgt gggaaggccc gcctccctcc tgatgtcctc     8820

agatgggtgg agcttgctaa gctgtataga tcaattggag aatacgacgt cctccgtggg     8880

atttttacca gtgagatagg aacaaagcaa atcactcaga gtgcattatt agcagaagcc     8940

agaagtgatt attctgaagc tgctaagcag tatgatgagg ctctcaataa acaagactgg     9000

gtagatggtg agcccacaga agccgagaag gatttttggg aacttgcatc ccttgactgt     9060

tacaaccacc ttgctgagtg gaaatcactt gaatactgtt ctacagccag tatagacagt     9120

gagaaccccc cagacctaaa taaaatctgg agtgaaccat tttatcagga aacatatcta     9180

ccttacatga tccgcagcaa gctgaagctg ctgctccagg gagaggctga ccagtccctg     9240

ctgacattta ttgacaaagc tatgcacggg gagctccaga aggcgattct agagcttcat     9300

tacagtcaag agctgagtct gctttacctc ctgcaagatg atgttgacag agccaaatat     9360

tacattcaaa atggcattca gagttttatg cagaattatt ctagtattga tgtcctctta     9420

caccaaagta gactcaccaa attgcagtct gtacaggctt taacagaaat tcaggagttc     9480

atcagcttta taagcaaaca aggcaattta tcatctcaag ttccccttaa gagacttctg     9540

aacacctgga caaacagata tccagatgct aaaatggacc caatgaacat ctgggatgac     9600

atcatcacaa atcgatgttt ctttctcagc aaaatagagg agaagcttac ccctcttcca     9660

gaagataata gtatgaatgt ggatcaagat ggagacccca gtgacaggat ggaagtgcaa     9720

gagcaggaag aagatatcag ctccctgatc aggagttgca agttttccat gaaaatgaag     9780

atgatagaca gtgcccggaa gcagaacaat ttctcacttg ctatgaaact actgaaggag     9840

ctgcataaag agtcaaaaac cagagacgat tggctggtga gctgggtgca gagctactgc     9900

cgcctgagcc actgccggag ccggtcccag ggctgctctg agcaggtgct cactgtgctg     9960

aaaacagtct ctttgttgga tgagaacaac gtgtcaagct acttaagcaa aaatattctg    10020

gctttccgtg accagaacat tctcttgggt acaacttaca ggatcatagc gaatgctctc    10080

agcagtgagc cagcctgcct tgctgaaatc gaggaggaca aggctagaag aatcttagag    10140

ctttctggat ccagttcaga ggattcagag aaggtgatcg cgggtctgta ccagagagca    10200

ttccagcacc tctctgaggc tgtgcaggcg gctgaggagg aggcccagcc tccctcctgg    10260

agctgtgggc ctgcagctgg ggtgattgat gcttacatga cgctggcaga tttctgtgac    10320

caacagctgc gcaaggagga agagaatgca tcagttattg attctgcaga actgcaggcg    10380

tatccagcac ttgtggtgga gaaaatgttg aaagctttaa aattaaattc caatgaagcc    10440

agattgaagt ttcctagatt acttcagatt atagaacggt atccagagga gactttgagc    10500

ctcatgacaa aagagatctc ttccgttccc tgctggcagt tcatcagctg gatcagccac    10560

atggtggcct tactggacaa agaccaagcc gttgctgttc agcactctgt ggaagaaatc    10620

actgataact acccgcaggc tattgtttat cccttcatca taagcagcga aagctattcc    10680

ttcaaggata cttctactgg tcataagaat aaggagtttg tggcaaggat taaaagtaag    10740

ttggatcaag gaggagtgat tcaagatttt attaatgcct tagatcagct ctctaatcct    10800

gaactgctct ttaaggattg gagcaatgat gtaagagctg aactagcaaa aacccctgta    10860

aataaaaaaa acattgaaaa aatgtatgaa agaatgtatg cagccttggg tgacccaaag    10920

gctccaggcc tgggggcctt tagaaggaag tttattcaga cttttggaaa agaatttgat    10980

aaacattttg ggaaaggagg ttctaaacta ctgagaatga agctcagtga cttcaacgac    11040

attaccaaca tgctactttt aaaaatgaac aaagactcaa agccccctgg gaatctgaaa    11100

gaatgttcac cctggatgag cgacttcaaa gtggagttcc tgagaaatga gctggagatt    11160

cccggtcagt atgacggtag gggaaagcca ttgccagagt accacgtgcg aatcgccggg    11220

tttgatgagc gggtgacagt catggcgtct ctgcgaaggc ccaagcgcat catcatccgt    11280

ggccatgacg agagggaaca ccctttcctg gtgaagggtg gcgaggacct gcggcaggac    11340

cagcgcgtgg agcagctctt ccaggtcatg aatgggatcc tggcccaaga ctccgcctgc    11400

agccagaggg ccctgcagct gaggacctat agcgttgtgc ccatgacctc caggttagga    11460

ttaattgagt ggcttgaaaa tactgttacc ttgaaggacc ttcttttgaa caccatgtcc    11520

caagaggaga aggcggctta cctgagtgat cccagggcac cgccgtgtga atataaagat    11580

tggctgacaa aaatgtcagg aaaacatgat gttggagctt acatgctaat gtataagggc    11640

gctaatcgta ctgaaacagt cacgtctttt agaaaacgag aaagtaaagt gcctgctgat    11700

ctcttaaagc gggccttcgt gaggatgagt acaagccctg aggctttcct ggcgctccgc    11760

tcccacttcg ccagctctca cgctctgata tgcatcagcc actggatcct cgggattgga    11820

gacagacatc tgaacaactt tatggtggcc atggagactg gcggcgtgat cgggatcgac    11880

tttgggcatg cgtttggatc cgctacacag tttctgccag tccctgagtt gatgcctttt    11940

cggctaactc gccagtttat caatctgatg ttaccaatga aagaaacggg ccttatgtac    12000

agcatcatgg tacacgcact ccgggccttc cgctcagacc ctggcctgct caccaacacc    12060

atggatgtgt ttgtcaagga gccctccttt gattggaaaa attttgaaca gaaaatgctg    12120

aaaaaaggag ggtcatggat tcaagaaata aatgttgctg aaaaaaattg gtacccccga    12180

cagaaaatat gttacgctaa gagaaagtta gcaggtgcca atccagcagt cattacttgt    12240

gatgagctac tcctgggtca tgagaaggcc cctgccttca gagactatgt ggctgtggca    12300

cgaggaagca aagatcacaa cattcgtgcc caagaaccag agagtgggct ttcagaagag    12360

actcaagtga agtgcctgat ggaccaggca acagacccca acatccttgg cagaacctgg    12420

gaaggatggg agccctggat gtgaggtctg tgggagtctg cagatagaaa gcattacatt    12480

gtttaaagaa tctactatac tttggttggc agcattccat gagctgattt tcctgaaaca    12540

ctaaagagaa atgtcttttg tgctacagtt tcgtagcatg agtttaaatc aagattatga    12600

tgagtaaatg tgtatgggtt aaatcaaaga taaggttata gtaacatcaa agattaggtg    12660

aggtttatag aaagatagat atccaggctt accaaagtat taagtcaaga atataatatg    12720

tgatcagctt tcaaagcatt tacaagtgct gcaagttagt gaaacagctg tctccgtaaa    12780

tggaggaaat gtggggaagc cttggaatgc ccttctggtt ctggcacatt ggaaagcaca    12840

ctcagaaggc ttcatcacca agattttggg agagtaaagc taagtatagt tgatgtaaca    12900

ttgtagaagc agcataggaa caataagaac aataggtaaa gctataatta tggcttatat    12960

ttagaaatga ctgcatttga tattttagga tatttttcta ggttttttcc tttcatttta    13020

ttctcttcta gttttgacat tttatgatag atttgctctc tagaaggaaa cgtctttatt    13080

taggagggca aaaattttgg tcatagcatt cacttttgct attccaatct acaactggaa    13140

gatacataaa agtgctttgc attgaatttg ggataacttc aaaaatccca tggttgttgt    13200

tagggatagt actaagcatt tcagttccag gagaataaaa gaaattccta tttgaaatga    13260

attcctcatt tggaggaaaa aaagcatgca ttctagcaca acaagatgaa attatggaat    13320

acaaaagtgg ctccttccca tgtgcagtcc ctgtcccccc ccgccagtcc tccacaccca    13380

aactgtttct gattggcttt tagctttttg ttgttttttt ttttccttct aacacttgta    13440

tttggaggct cttctgtgat tttgagaagt atactcttga gtgtttaata aagttttttt    13500

ccaaaagta                                                            13509


<210>  661
<211>  4301
<212>  DNA
<213>  homo sapiens

<400>  661
tagagaacgt ggctcccgcg ggggcgctcg gagccgccgc acaggtagcg agagcgcggc       60

gccttctcct tcctttgtga gccgccgggc agggcaccga cctcgggttc tcccggcgcc      120

tccactgcag ggatctctag cctcgcacct cctcccctcg tcgcctgccc accctctgct      180

cctctcctgg cgccggggac cctgcccctt tgcgcctttt cctggctctg cctcggcttc      240

catttttctc tgcttccgaa aagccagtgg ggaagggcgg gggagacctg ccagtcctcc      300

cagacttctc ccgggttgct ccagctggcc ctcctcgccc cttcccggga gaggcacatg      360

gagagacatg aatcagggga gtggactgga cctgctgaag atctcatatg gaaaaggagc      420

cagaaggaaa aacagattta aaggatctga tggaagcacg tcatctgata ctacctcaaa      480

tagttttgtt cgccagggtt cggcagactc ctacactagc cgtccatccg attccgatgt      540

atctctggag gaggaccggg aggcagtgcg cagagaagcg gagcggcagg cccaggcaca      600

gttggaaaaa gcaaagacaa agcccgttgc atttgcggtt cggacaaatg tcagctacag      660

tgcggcccat gaagatgatg ttccagtgcc tggcatggcc atctcattcg aagcaaaaga      720

ttttctgcat gttaaggaaa aatttaacaa tgactggtgg atagggcgat tggtaaaaga      780

aggctgtgaa atcggattca ttccaagccc agtcaaacta gaaaacatga ggctgcagca      840

tgaacagaga gccaagcaag ggaaattcta ctccagtaaa tcaggaggaa attcatcatc      900

cagtttgggt gacatagtac ctagttccag aaaatcaaca cctccatcat ctgctataga      960

catagatgct actggcttag atgcagaaga aaatgatatt ccagcaaacc accgctcccc     1020

taaacccagt gcaaacagtg taacgtcacc ccactccaaa gagaaaagaa tgcccttctt     1080

taagaagaca gagcacactc ctccgtatga tgtggtacct tccatgcgac cagtggtcct     1140

agtgggccct tctctgaagg gctacgaggt cacagatatg atgcaaaaag cgctgtttga     1200

ttttttaaaa cacagatttg aagggcggat atccatcaca agggtcaccg ctgacatctc     1260

gcttgccaaa cgctcggtat taaacaatcc cagtaagcac gcaataatag aaagatccaa     1320

cacaaggtca agcttagcgg aagttcagag tgaaatcgaa aggatttttg aacttgcaag     1380

aacattgcag ttggtggtcc ttgacgcgga tacaattaat catccagctc aactcagtaa     1440

aacctccttg gcccctatta tagtatatgt aaagatttct tctcctaagg ttttacaaag     1500

gttaataaaa tctcgaggga aatctcaagc taaacacctc aacgtccaga tggtagcagc     1560

tgataaactg gctcagtgtc ctccagagct gttcgatgtg atcttggatg agaaccagct     1620

tgaggatgcc tgtgagcacc ttgccgacta tctggaggcc tactggaagg ccacccatcc     1680

tcccagcagt agcctcccca accctctcct tagccgtaca ttagccactt caagtctgcc     1740

tcttagcccc accctagcct ctaattcaca gggttctcaa ggtgatcaga ggactgatcg     1800

ctccgctcct atccgttctg cttcccaagc tgaagaagaa cctagtgtgg aaccagtcaa     1860

gaaatcccag caccgctctt cctcctcagc cccacaccac aaccatcgca gtgggacaag     1920

tcgcggcctc tccaggcaag agacatttga ctcggaaacc caggagagtc gagactctgc     1980

ctacgtagag ccaaaggaag attattccca tgaccacgtg gaccactatg cctcacaccg     2040

tgaccacaac cacagagacg agacccacgg gagcagtgac cacagacaca gggagtcccg     2100

gcaccgttcc cgggacgtgg atcgagagca ggaccacaac gagtgcaaca agcagcgcag     2160

ccgtcataaa tccaaggatc gctactgtga aaaggatgga gaagtgatat caaaaaaacg     2220

gaatgaggct ggggagtgga acagggatgt ttacatccgc caatgagttt tgcccgtttg     2280

tgtttttttt tttttttttt tgaagtcttg tataactaac agcatcccca aaacaaagtc     2340

tttggggtct acactgcaat catatgtgat ctgtcttgta atattttgta ttattgctgt     2400

tgcttgaata gcaatagcat ggatagagta ttgagatact ttttcttttg taagtgctac     2460

ataaattggc ctggtatggc tgcagtcctc cggttgcata ctggactctt caaaaactgt     2520

tttgggtagc tgccacttga acaaaatctg ttgccaccca ggtgatgtta gtgttttaag     2580

aaatgtagtt gatgtatcca acaagccaga atcagcacag ataaaaagtg gaatttcttg     2640

tttctccaga tttttaatac gttaatacgc aggcatctga tttgcatatt cattcatgga     2700

ccactgtttc ttgcttgtac ctctggctga ctaaatttgg ggacagattc agtcttgcct     2760

tacacaaagg ggatcataaa gttagaatct attttctatg tactagtact gtgtactgta     2820

tagacagttt gtaaatgtta tttctgcaaa caaacacctt cttattatat atataatata     2880

tatatatatc agtttgatca cactatttta gagtcttaat gccaagtcag cagatttgct     2940

ttatgaatta cagggactag aaatgcccac attcaggaaa tttgtaataa cattgtctag     3000

acacctatcc tcattctagt agaaagtgtg tacatactgt aaatatgtgt gattgcttga     3060

cttgaaaagg tttgaattct gaatgttata ccatccttgt aagtaagttt gtaatttcca     3120

ccataaatta tggtaaatat aaaactccag aggttgttct actccataca gttcacactg     3180

attgtgacac attcttagta gctagtgtct gttctagtca ctgcactgga gtctacgagc     3240

cggaactcgc tatatgcacg tgtgtgtgtc cgtatgtaag aaagtgtgca ccgagtgact     3300

gaatggttga gatgaattgg aatgctgaag actaacgaag aaactagaga ctgatatcga     3360

gcattctgcc cacctcgctc tgtatttaat taattgtgct atatgttgct ttaacaaccc     3420

attgagcagt cagggaatgt gagtaagctt gctgccaaag gtaactagga aagcattcat     3480

ctgctgcctc cttgtttttg ctcctagaga gtgaaaatac aggcaatttt actgtgagtg     3540

tttcactgga aatgtacaat ctttgtgtgt tagagtattt gttttagtaa gaaatgttta     3600

cacagcttgt ggaattattt cgtgggaaaa taaattttta taacttctcc cacttcaatt     3660

tctaaccttg cctattgttc ctgttgtttg tttacctccc agttacctac cattcctccc     3720

caccaccgac tccagcaggt tcactgtctg tcagaaccca gaagtgcttc ttataaccaa     3780

agtttctgtt cttcagaaga aatcagggca aaatggggtg acttgaagtg aataaaatgt     3840

taagaatatt atcctacata agacatgtac acagaagggg aaccttgaag acattatctc     3900

catgcctcaa ttacactgct gtaagaagct tacaatgtca tcatgtttaa ggctaagacc     3960

ttttccgtgt ctcaagtgta tattttgtcc agttataact ggatggtaag acagtattaa     4020

gagtgcaagt acctggcact tgaagtttgt cccaggaaaa tgcctgtgta taattaccta     4080

acttcagatc tgcacattaa cttatttaac aaaataaatc agccgggcgc agtggctcat     4140

gcctgtaatc ccagcaattt gggaggctga ggagggtgga tcacctgagg tcaggagttc     4200

aagaccagcc tggccaacgt ggcgaaaccc cgtctctact aaaaagataa aaaattagcc     4260

aggtgtggtg gtgcacacct gtaatcccag ctacttggga g                         4301


<210>  662
<211>  2879
<212>  DNA
<213>  homo sapiens

<400>  662
atcctgtccc agcctgcttc cccgccggcc gccgccctcc tccccgggag agagcgaggc       60

gcgcgggtcc ctctgcgcca cccccgcccc cgccccttcc gagcaaactt ttggcaccca      120

ccgcagccca gcgcgcgttc gtgctccgca gggcgcgcct ctctccgcca atgccaggcg      180

cgcgggggag ccattaggag gcgaggagag aggagggcgc agctcccgcc cagcccagcc      240

ctgcccagcc ctgcccggag gcagacgcgc cggaaccggg acgcgataaa tatgcagagc      300

ggaggcttcg cgcagcagag cccgcgcgcc gcccgctccg ggtgctgaat ccaggcgtgg      360

ggacacgagc caggcgccgc cgccggagcc agcggagccg gggccagagc cggagcgcgt      420

ccgcgtccac gcagccgccg gccggccagc acccagggcc ctgcatgcca ggtcgttgga      480

ggtggcagcg agacatgcac ccggcccgga agctcctcag cctcctcttc ctcatcctga      540

tgggcactga actcactcaa gtgctgccca ccaaccctga ggagagctgg caggtgtaca      600

gctctgccca ggacagcgag ggcaggtgta tctgcacagt ggtcgctcca cagcagacca      660

tgtgttcacg ggatgcccgc acaaaacagc tgaggcagct actggagaag gtgcagaaca      720

tgtctcaatc catagaggtc ttggacaggc ggacccagag agacttgcag tacgtggaga      780

agatggagaa ccaaatgaaa ggactggagt ccaagttcaa acaggtggag gagagtcata      840

agcaacacct ggccaggcag tttaaggcga taaaagcgaa aatggatgaa cttaggcctt      900

tgatacctgt gttggaagag tacaaggccg atgccaaatt ggtattgcag tttaaagagg      960

aggtccagaa tctgacgtca gtgcttaacg agctgcaaga ggaaattggc gcctatgact     1020

acgatgaact tcagagcaga gtgtccaatc ttgaagaaag gctccgtgca tgcatgcaaa     1080

aactagcttg cgggaagttg acgggcatca gtgaccccgt gactgtcaag acctccggct     1140

cgaggttcgg atcctggatg acagaccctc tcgcccctga aggcgataac cgggtgtggt     1200

acatggacgg ctatcacaac aaccgcttcg tacgtgagta caagtccatg gttgacttca     1260

tgaacacgga caatttcacc tcccaccgtc tcccccaccc ctggtcgggc acggggcagg     1320

tggtctacaa cggttctatc tacttcaaca agttccagag ccacatcatc atcaggtttg     1380

acctgaagac agagaccatc ctcaagaccc gcagcctgga ctatgccggt tacaacaaca     1440

tgtaccacta cgcctggggt ggccactcgg acatcgacct catggtggac gagagcgggc     1500

tgtgggccgt gtacgccacc aaccagaacg ctggcaacat cgtggtcagt aggctggacc     1560

ccgtgtccct gcagaccctg cagacctgga acacgagcta ccccaagcgc agcgccgggg     1620

aggccttcat catctgcggc acgctgtacg tcaccaacgg ctactcaggg ggtaccaagg     1680

tccactatgc ataccagacc aatgcctcca cctatgaata catcgacatc ccattccaga     1740

acaaatactc ccacatctcc atgctggact acaaccccaa ggaccgggcc ctgtatgcct     1800

ggaacaacgg ccaccagatc ctctacaacg tgaccctctt ccacgtcatc cgctccgacg     1860

agttgtagct ccctcctcct ggaagccaag ggcccacgtc ctcaccacaa agggactcct     1920

gtgaaactgc tgccaaaaag ataccaataa cactaacaat accgatcttg aaaaatcatc     1980

agcagtgcgg attctgacat cgagggatgg cattacctcc gtgtttctcc ctttcgagcc     2040

ggcgggccac agacgtcgga agaaactccc gtatttgcag ctggaactgc agcccacggc     2100

gccccggttt tcctccccgc cctgtccctc tctggtcaaa caacatacta aagaggcgag     2160

gcaatgactg ttggccagtt ctcaccgggg aaaaacccac tgttaggatg gcatgaacat     2220

ttccttagat cgtggtcagc tccgaggaat gtggcgtcca ggctctttga gagccatggg     2280

ctgcacccgg ccgtaggcta gtgtaactcg catcccattg cagtgccgtt tcttgactgt     2340

gttgctgtct cttagattaa ccgtgctgag gctccacata gctcctggac ctgtgtctag     2400

tacatactga agcgatggtc agagtgtgta gagtgaagtt gctgtgccca cattgtttga     2460

actcgcgtac cccgtagata cattgtgcaa cgttcttctg ttattccctt gaggtggtaa     2520

cttcgtatgt tcagtttatg cgatgattgt tgtaaatgca atgccgtagt ttggattaat     2580

aagtggatgg tttttgtttc taaaaagaaa aaaaaaatca gtgttcaccc ttatagagac     2640

atagtcaagt tcatgttgat aataatcaaa ggaattactc tcttcttgtt aaattagcta     2700

aatcatgtaa ccgcagatag gaagggctcg cctggggaaa ctctggtttc cgatgggaca     2760

ggaaagtcat acgggcaaca gtatgcggaa agtacgtttt ttaagtaaaa aacaaaggca     2820

aactttgtac tatccagtta tctaaggaac aataaaaaca ttaggagatc ttttaaaaa      2879


<210>  663
<211>  2099
<212>  DNA
<213>  homo sapiens

<400>  663
agaaagtagc agaaagtgag gctggcaggc ggcggcaaag gagccggcgc gcggcggcgg       60

caggaagtct gtgcccgaga acagcagaaa taagagccag ggagggaccg cggccgcggc      120

ggcggcggcg agagcgaaag aggaaactgc agaggaggaa gctgcgccgc agcccgagcc      180

gcccggcatc cccgccgcct ctgcgcccgc gccgcgcccc cggcgccccc tccccagcgc      240

gcccccggcc gctcctccgc gccgcgctcg tcggccatgg cccgggagaa cggcgagagc      300

agctcctcct ggaaaaagca agctgaagac atcaagaaga tcttcgagtt caaagagacc      360

ctcggaaccg gggccttttc cgaagtggtt ttagctgaag agaaggcaac tggcaagctc      420

tttgctgtga agtgtatccc taagaaggcg ctgaagggca aggaaagcag catagagaat      480

gagatagccg tcctgagaaa gattaagcat gaaaatattg ttgccctgga agacatttat      540

gaaagcccaa atcacctgta cttggtcatg cagctggtgt ccggtggaga gctgtttgac      600

cggatagtgg agaaggggtt ttatacagag aaggatgcca gcactctgat ccgccaagtc      660

ttggacgccg tgtactatct ccacagaatg ggcatcgtcc acagagacct caagcccgaa      720

aatctcttgt actacagtca agatgaggag tccaaaataa tgatcagtga ctttggattg      780

tcaaaaatgg agggcaaagg agatgtgatg tccactgcct gtggaactcc aggctatgtc      840

gctcctgaag tcctcgccca gaaaccttac agcaaagccg ttgactgctg gtccatcgga      900

gtgattgcct acatcttgct ctgcggctac cctccttttt atgatgaaaa tgactccaag      960

ctctttgagc agatcctcaa ggcggaatat gagtttgact ctccctactg ggatgacatc     1020

tccgactctg caaaagactt cattcggaac ctgatggaga aggacccgaa taaaagatac     1080

acgtgtgagc aggcagctcg gcacccatgg atcgctggtg acacagccct caacaaaaac     1140

atccacgagt ccgtcagcgc ccagatccgg aaaaactttg ccaagagcaa atggagacaa     1200

gcatttaatg ccacggccgt cgtcagacat atgagaaaac tacacctcgg cagcagcctg     1260

gacagttcaa atgcaagtgt ttcgagcagc ctcagtttgg ccagccaaaa agactgtgcg     1320

tatgtagcaa aaccagaatc cctcagctga cactgaagac gagcctgggg tggagaggag     1380

ggagccggca tctgccgagc acctcctgtt tgccaggcgc tttctatact taatcccatg     1440

tcatgcgacc ctaggacttt ttttaacatg taatcactgg gctgggtgca gtggctcacg     1500

cctgtaatcc caacactttg ggaggctgag gcaggaggac tgtttgagtt caggagtttt     1560

aagaccagcc tgaccaacat ggtgaaaccc catctctact aaaatataaa aattagccgg     1620

gtgtggtggc gagcacctgt aatgtcagct acttgggagg ctgaggcagg agaatcactt     1680

gaacccagga agcggaggtt gcaatgagct gagatcacac cactgcactc cagcctgggt     1740

gacagattga gactccctct caaaaaaaaa aaagaaaaat cattgaacac tcgtggaacc     1800

ctaggtattg ctatttccat ttacagttga ggaatccagg gctcaagtcc tcgcagccat     1860

gtctgtctgg ataaaggcct ggactctttc tcatctccat ccttccctct gatttacctc     1920

tcattgtaca gtcactcttg cggattgagg aagggagagc agagcctcag gacagcctcc     1980

tgccattgac ttccataatg tatatatttt ggatgcagac aatgataatt tgagctcatt     2040

tatgtgaagt gcattgactt tgcaataaaa gtaatagtat ttcattgtca aaaaaaaaa      2099


<210>  664
<211>  3080
<212>  DNA
<213>  homo sapiens

<400>  664
tcccctttat ttccactccc cacccgcgtg gctttgctct ccctctcccc cctcagctcg       60

tctgtatttg gagctccgga agctgccggc gactctcccc tggagcagcg tgactgacac      120

cggctcctat tcagctggga ggagggagag gggaggagaa ggggagggcc gcgggaggag      180

ggtacgagtg gccgaccacg gatttgcatt gccgaggacg ggaccccagg gcagcgaagc      240

agaatggcca acatgcaggg actggtggaa agactggaac gagctgtcag ccgcctggag      300

tcgctgtctg cagagtccca caggccccct gggaactgcg gggaagtcaa tggtgtcatt      360

gcaggtgtgg caccctccgt ggaagccttt gacaagctga tggacagtat ggtggccgag      420

tttttaaaga acagtaggat ccttgctggg gacgtggaga cccatgcaga aatggtgcac      480

agtgctttcc aggcccagcg ggctttcctt ctgatggcct ctcagtacca acaaccccac      540

gagaatgacg tggccgcact tctgaaaccc atatcggaaa agattcagga aatccaaact      600

ttcagagaga gaaaccgggg gagtaacatg tttaatcatc tttcggccgt cagcgaaagc      660

atccctgccc ttggatggat agctgtgtct cccaaacctg gtccttatgt caaggagatg      720

aatgacgctg ccacctttta cactaacagg gtcttaaagg actacaaaca cagtgatttg      780

cgtcatgtgg attgggtgaa gtcatatttg aacatttgga gtgaacttca agcatacatc      840

aaggaacacc acaccacggg cctcacatgg agcaaaacag gtcctgtagc atccacagta      900

tcagcgtttt ctgtcctctc ctctgggcct ggccttcctc caccccctcc tcctctgcct      960

cctccagggc cacctccact tttcgagaat gaaggcaaaa aagaggaatc ttctccttca     1020

cgctcagctt tatttgccca acttaaccag ggagaagcaa ttacaaaagg gctccgccat     1080

gtcacagatg accagaagac atacaaaaat cccagcctgc gggctcaagg agggcaaact     1140

caatctccca ccaaaagtca cactccaagt cccacatctc ctaaatctta tccttctcaa     1200

aaacatgccc cagtgttgga gttggaagga aagaaatgga gagtggagta ccaagaggac     1260

aggaatgacc ttgtgatttc agagactgag ctgaaacaag tggcttacat tttcaaatgc     1320

gaaaaatcaa ctattcagat aaaagggaaa gtaaactcca ttataattga caactgtaaa     1380

aaactcggcc tggtgtttga caatgtggtg ggcattgtgg aagtgatcaa ctcccaggac     1440

attcaaatcc aggtaatggg gagagtgcca acaatttcca ttaataagac agaaggttgc     1500

cacatatacc tcagtgaaga tgcattagac tgtgagatcg tgagcgccaa gtcatctgaa     1560

atgaacatac ttatccctca ggatggtgat tatagagaat ttcccattcc tgaacagttc     1620

aagacagcat gggatggatc caagttaatc actgaacctg cagaaattat ggcctaactt     1680

cctgagagac cgaaccccct cacctgaatc cccctctatc aaacaaacaa aaaagcagca     1740

gtaaagagct agaagttgca gtagccccta ctgctttagc tttggcctcc aacgattctg     1800

tgctatagat acagcactgt ttctggcacg cctcgtgggc attttgaaat atttaacgtt     1860

tcctcatgat ttgcctttgt gtgtgatttt agttccacat gatgacttgt gaacattagg     1920

gatttaaagg aaaaaaaaaa agaattctgt tcccctcata tcatgaacac agtaactgat     1980

aggtaaaaag actgcatgat tcacttttac acttatattt cattgctagt taaaaaataa     2040

aacctttgag aatctaagat gtacattttt accttttagg caatttcaat ataatgtaga     2100

agtagtagtg tgccctgaaa aatgtacacg ttttttctta ttgttaccac atgttcacct     2160

ttatcagcgt ggatactgtc agcatgagta catatttcaa cccacgcttg taaaagacat     2220

aagagtttat aaaggaccaa attcagttcc ttggtccttg gaagacctat attctctgta     2280

gttactgaaa accgaaagtc aattctaatt attcatctta catatttttc caccatgtca     2340

tttgaaaact tgcttttctt ctgcataaga gattcttatg ccaaaaacat taaacagaag     2400

aaatcatttt ttttgctatg taatacctcg caactttgct ctaaaatcaa gctcagttat     2460

tattttccaa gtttgaacat gttaaatatc agatgccttg taaattatgt ctttaacgtt     2520

ttcttataga ctaatttcct cttttccacc tgccagactt gctaaccaag ctcgaaaatg     2580

aacatgaaaa agccatacat gtattatttc tcctaaaacc taaggcatta tctgttggtt     2640

tggcttgctg ctcctatttt gtagtcttga tagtagatgc ttcttcagcg taagagtagc     2700

tatgatattc ctttttatct tttcagtaca tagtgctgaa aaatctgcaa cttcttggat     2760

catatttaat gaattatagt ataatgcttg caggcccagt acaagcatat atattgtgcc     2820

tcttacagcc tttggaatac attgtttcca ttttttaaat atcttctata tccatatagt     2880

attcaaatta ttaatgctca tgtaccaagg ttttgctata aaagttttgt ctgtatgaat     2940

aatgtggctt tagtaaataa tcatttttca actgtaaact tattctgaaa taaagtaaaa     3000

ttctaattgt ttaaatactg tgatgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa                                                 3080


<210>  665
<211>  4504
<212>  DNA
<213>  homo sapiens

<400>  665
agtcagaccc aggaggagtg aggtcaattg ccctttagtc ccaggactaa ccggaagctt       60

ctgcaacagg aggacattga aaataagatg gaacccatcc acataaggat ttgcctcaaa      120

gggcactgca aaaattgaac agaggaatcc caaggaagct gcctgaattt gcctgtatac      180

tctcgttctg cgacttataa aggaccagac aaatcaaatt agtggttttg gtttccgcca      240

gctgtggatg cctttgacat tatgaccgca gaggattcca ccgcagccat gagcagtgac      300

tcggccgccg ggtcctccgc caaggtgccc gagggcgtgg cgggcgcgcc caacgaggca      360

gcactgctgg cgctgatgga gcgcacgggc tacagcatgg tgcaagagaa cgggcagcgc      420

aagtacggcg gcccaccgcc cggctgggag ggcccgcacc cgcagcgtgg ctgcgaggtc      480

ttcgtgggca agatcccgcg cgacgtgtac gaggacgagc tggtgcccgt gttcgaggcc      540

gtgggccgca tctacgagct gcgcctcatg atggactttg acggcaagaa ccgcggctac      600

gccttcgtca tgtactgcca caagcacgag gccaagcgcg cagtgcgtga gctcaacaac      660

tacgagatcc gcccgggccg cctgctcggc gtgtgctgca gcgtggacaa ctgccgcctc      720

ttcatcggcg ggatccccaa gatgaagaag cgcgaggaaa tcctggagga gattgccaag      780

gtcaccgagg gcgtgctgga cgtgatcgtc tacgccagcg cggccgacaa gatgaagaac      840

cgcggcttcg ccttcgtgga gtacgagagc caccgcgcgg ctgccatggc tcgccgcaag      900

ctcatgcctg gccgcatcca gctgtggggc caccagatcg ccgtggactg ggccgaacct      960

gagatcgacg tggacgagga cgtgatggag accgtgaaga tcctctacgt gcgcaacctc     1020

atgatcgaga ccaccgagga caccatcaag aagagcttcg gccagttcaa ccccggctgc     1080

gtggagcgcg tcaagaagat ccgcgactac gccttcgtgc acttcaccag ccgcgaggat     1140

gccgtgcatg ccatgaacaa cctcaacggc actgagctgg agggctcgtg cctggaggtc     1200

acgctggcca agcccgtgga caaggagcag tactcgcgct accagaaggc agccaggggc     1260

ggcggcgcgg ctgaggcagc gcagcagccc agctacgtgt actcctgcga cccctacaca     1320

ctggcctact acggctaccc ctacaacgcg ctcattgggc ccaacaggga ctactttgtg     1380

aaagtagcca tccctgccat tggggctcag tattccatgt ttccagcagc tccagcccct     1440

aaaatgattg aagatggcaa aatccacaca gtggagcaca tgatcagccc cattgctgtg     1500

cagccagacc cagccagtgc tgctgccgcc gcagccgcgg ccgcagccgc cgcagccgct     1560

gtcattccca ctgtgtcgac gccaccacct ttccagggcc gcccaataac tccagtatac     1620

acggtggctc caaacgttca gagaattcct actgccggga tctacggggc cagttacgtg     1680

ccatttgctg ctccagctac agccacgatc gccacactac agaagaacgc ggcagccgcg     1740

gccgccatgt atggaggata cgcaggctac atacctcagg ccttccctgc tgctgccatt     1800

caggtcccca tccccgacgt ctaccagaca tactgaggct ggtgaccagc acgaagacag     1860

accacacaaa caccactgaa ggaacgcttg actatttatg aagaaggaac atgttggatt     1920

cacacatgca acctgaaagt gaagaatgtt agcagattta tttctgaatt attttatata     1980

catgaagttt tcactagttt tttaagacta ttttcaactt agcatgccta cgttcataca     2040

tttccaaaag acttgcaatg gttcgtgcct tcattccatc ttttaaaaat ttgtatgctg     2100

tactacattt gtatagaggt ttttgttgtt gtttttttaa ggatatattt tcagtatgaa     2160

ggttattttc ttaacttctg cactccagag atttctattt tgtagtacct tcaataatat     2220

atcaactata tattaaaaaa gcacacttga ggagctaggg aactattttg aaaaatatat     2280

acaatattta aagatacaaa cagtagtgct taaaaatact acataaagca ttattttaaa     2340

ggttatactg gaaagtgcaa ttttaaaatg agtaaaacct ctgtatttct gctggcatta     2400

agggttgatg gtgttaccat gtatcatcat ggcggtacta ttttttaaaa gaaattaaac     2460

actggatctc tccttaagcc aacattgaaa agacttgccg cacttctgag tccaaacact     2520

ggaaagctct cctttgccac cgttagccgg ggctcattct ccatgtgcct tagccttaaa     2580

catgccccca ctcccacatc tctcaccctg tcccctcctc cccagattcc caatcccacc     2640

gcaatgtttg gcaagcctag gactgataag tagctctgat agaggagctg gtggctttta     2700

tacttcttcc tgggtttttg ttggggtttg ttgtttcgtt gttttttgtt tttttttttg     2760

tttggttggg gaagtattgt cttctacgtg tgctattttc agtagcagag taagcacaag     2820

gttttaatcg agttgcataa gacacctttg catagctatt taattgccca atgtaaaact     2880

ttaatgccat ttctaatgct tttattcatt tttgaagtat gagtttgtag ggacaaagaa     2940

tgtatgttat cgtagacaag acccccagag actcttttca gcagaaagtt atgcttctag     3000

ttgccttacc atgtttcttg caaaactgtc catggtcctc aagggtgttg gaaacattat     3060

gtttattaaa tgggcctctc ttcctttgct gtgcacttga tgggtgaact ggattggggt     3120

gtgcacatcc aggaggagga ggagagacct gtagaagttt aaagatagtt tgtaaatatc     3180

ttctaatgct tgtttttagt ccttttatgt tggagaagtt catggtatgt agtttaatgc     3240

aaaatgaaac cattttattt caatgttatt aaaaaggttt gttttattag gaagttaatg     3300

tattgttgca gtgttttgtg cctgtttaaa ggcttttgtt tagcagagtg aatgtaaaat     3360

acagtaaaat gttaagattg tcatctactt tttaaaaaaa aatatcaact tggaattgtt     3420

ttttaaaggc tcaatcaagg aagtgaggtg tgcaataagg tagcaagtaa aacgcagttg     3480

cgtttttatg tcatgttaga gatccataca attttccact cacgggattt ttgttgatgg     3540

ctgaattctt gtggattcat aagaggatca tgcccttagc aagtactttt gttttgtttt     3600

aaattaagag attcccaaat gcctttttcc ccctcatctt gaaatgagat gagtttttat     3660

gtgtaagcaa tatttattta actattctat aaaattattg agtgcctact gaggccttta     3720

agcaccgcta acattccttt ccatcattct tttaaatgac ataaaataat tgtgcaatgt     3780

tcctgatgat gtaccccaca agctgcattc aaactcaaat ctgtgggaat gagtgactcg     3840

acaaaatgta attcggatca gatcctcatc ccctgactgt gtgaaaaaag tactctcctt     3900

ctagtgaagg attgtcacag agtttcactg gatgaaacta tgacccagta ttcttactgt     3960

attttacata tgcctgtaaa ttatttgcaa aaaagaagaa gaagaggaag aaagaaaaga     4020

aagaaaagaa agaaagaaag aaagaaagaa agaaagaaag aaagaaagaa agaaagaaag     4080

aaagaaaaag aaagaaagaa taaaaaaaaa tgataacatg gcaaccacca aactccctta     4140

aaaacaaaca ttggtgacat ggccaattaa gtatcagtga gcctcctatc tgggacttat     4200

ctgttcctat tgtttcaaaa ccatttcatg tacactactg aggtaagttt ataacttgaa     4260

atgtgaactt tttttttttt tagtgttaag aacaaactat ataaatgtaa aaaaaaagtt     4320

ttagagttct gttttcaaac attgctagtg gtttagttaa ctttagctgc tttatatttg     4380

aaaagctttt atttagatct tgctccattt acagtacatt cttaggatgt atgtagtaaa     4440

taaagctttc tttaaagcaa tcgcaagacc ttattttaaa ttgtgaaaaa aaaaaaaaaa     4500

aaaa                                                                  4504


<210>  666
<211>  823
<212>  DNA
<213>  homo sapiens

<400>  666
cacttccctc aacccttccc acaaactggg aggaaaactg agacctcctg gtcacccgcc       60

gccgggcctt ttagaaactc ccacaagctc tgccttccct ccctggtcct cttcagaccc      120

cctcttagtt cttcgcggct aacggctcgc gctcggggcc gggtgtggag ctggaacaga      180

gggctggcaa ggcgcgcatg cgcaccgagg gtggagccgc tgagcacaga accggaaact      240

tagagacaaa gttcggagcc ccgcccccgc cgcgcgccgc tgagttgtct ggccccgccg      300

acccacggcc cacgacccac cgacccacga atcggcccgg ccgtcgcgtg caccatgtct      360

ggctcctcca gcgtcgccgc tatgaagaaa gtggttcaac agctccggct ggaggccgga      420

ctcaaccgcg taaaagtttc ccaggcagct gcagacttga aacagttctg tctgcagaat      480

gctcaacatg accctctgct gactggagta tcttcaagta caaatccctt cagaccccag      540

aaagtctgtt cctttttgta gtaaaatgaa tctttcaaag gtttcccaaa ccactcctta      600

tgatccagtg aatattcaag agagctacat ttgaagcctg tacaaaagct tatccctgta      660

acacatgtgc cataatatac aaacttctac tttcgtcagt ccttaacatc tacctctctg      720

aattttcatg aatttctatt tcacaagggt aattgtttta tatacactgg cagcagcata      780

caataaaact tagtatgaaa cttttaaaaa aaaaaaaaaa aaa                        823


<210>  667
<211>  823
<212>  DNA
<213>  homo sapiens

<400>  667
cacttccctc aacccttccc acaaactggg aggaaaactg agacctcctg gtcacccgcc       60

gccgggcctt ttagaaactc ccacaagctc tgccttccct ccctggtcct cttcagaccc      120

cctcttagtt cttcgcggct aacggctcgc gctcggggcc gggtgtggag ctggaacaga      180

gggctggcaa ggcgcgcatg cgcaccgagg gtggagccgc tgagcacaga accggaaact      240

tagagacaaa gttcggagcc ccgcccccgc cgcgcgccgc tgagttgtct ggccccgccg      300

acccacggcc cacgacccac cgacccacga atcggcccgg ccgtcgcgtg caccatgtct      360

ggctcctcca gcgtcgccgc tatgaagaaa gtggttcaac agctccggct ggaggccgga      420

ctcaaccgcg taaaagtttc ccaggcagct gcagacttga aacagttctg tctgcagaat      480

gctcaacatg accctctgct gactggagta tcttcaagta caaatccctt cagaccccag      540

aaagtctgtt cctttttgta gtaaaatgaa tctttcaaag gtttcccaaa ccactcctta      600

tgatccagtg aatattcaag agagctacat ttgaagcctg tacaaaagct tatccctgta      660

acacatgtgc cataatatac aaacttctac tttcgtcagt ccttaacatc tacctctctg      720

aattttcatg aatttctatt tcacaagggt aattgtttta tatacactgg cagcagcata      780

caataaaact tagtatgaaa cttttaaaaa aaaaaaaaaa aaa                        823


<210>  668
<211>  2915
<212>  DNA
<213>  homo sapiens

<400>  668
ccgagttcag tcatactgca ccagctgagc aatgcatgga gtggacctgt aggcgacttg       60

catcgtcttc aacatgaaga tagccacagt gtcagtgctt ctgcccttgg ctctttgcct      120

catacaagat gctgccagta agaatgaaga tcaggaaatg tgccatgaat ttcaggcatt      180

tatgaaaaat ggaaaactgt tctgtcccca ggataagaaa ttttttcaaa gtcttgatgg      240

aataatgttc atcaataaat gtgccacgtg caaaatgata ctggaaaaag aagcaaaatc      300

acagaagagg gccaggcatt tagcaagagc tcccaaggct actgccccaa cagagctgaa      360

ttgtgatgat tttaaaaaag gagaaagaga tggggatttt atctgtcctg attattatga      420

agctgtttgt ggcacagatg ggaaaacata tgacaacaga tgtgcactgt gtgctgagaa      480

tgcgaaaacc gggtcccaaa ttggtgtaaa aagtgaaggg gaatgtaaga gcagtaatcc      540

agagcaggat gtatgcagtg cttttcggcc ctttgttaga gatggaagac ttggatgcac      600

aagggaaaat gatcctgttc ttggtcctga tgggaagacg catggcaata agtgtgcaat      660

gtgtgctgag ctgtttttaa aagaagctga aaatgccaag cgagagggtg aaactagaat      720

tcgacgaaat gctgaaaagg atttttgcaa ggaatatgaa aaacaagtga gaaatggaag      780

gcttttttgt acacgggaga gtgatccagt ccgtggccct gacggcagga tgcatggcaa      840

caaatgtgcc ctgtgtgctg aaattttcaa gcagcgtttt tcagaggaaa acagtaaaac      900

agatcaaaat ttgggaaaag ctgaagaaaa aactaaagtt aaaagagaaa ttgtgaaact      960

ctgcagtcaa tatcaaaatc aggcaaagaa tggaatactt ttctgtacca gagaaaatga     1020

ccctattcgt ggtccagatg ggaaaatgca tggcaacttg tgttccatgt gtcaagccta     1080

cttccaagca gaaaatgaag aaaagaaaaa ggctgaagca cgagctagaa acaaaagaga     1140

atctggaaaa gcaacctcat atgcagagct ttgcagtgaa tatcgaaagc ttgtgaggaa     1200

cggaaaactt gcttgcacca gagagaacga tcctatccag ggcccagatg ggaaagtgca     1260

tggcaacacc tgctccatgt gtgaggtctt cttccaagca gaagaagaag aaaagaaaaa     1320

gaaggaaggt aaatcaagaa acaaaagaca atctaagagt acagcttcct ttgaggagtt     1380

gtgtagtgaa taccgcaaat ccaggaaaaa cggacggctt ttttgcacca gagagaatga     1440

ccccatccag ggcccagatg gaaaaatgca tggcaacacc tgctccatgt gtgaggcctt     1500

ctttcaacaa gaagaaagag caagagcaaa ggctaaaaga gaagctgcaa aggaaatctg     1560

cagtgaattt cgggaccaag tgaggaatgg aacacttata tgcaccaggg agcataatcc     1620

tgtccgtggc ccagatggca aaatgcatgg aaacaagtgt gccatgtgtg ccagtgtgtt     1680

caaacttgaa gaagaagaga agaaaaatga taaagaagaa aaagggaaag tcgaggctga     1740

aaaagttaag agagaagcag ttcaggagct gtgcagtgaa tatcgtcatt atgtgaggaa     1800

tggacgactc ccctgtacca gagagaatga tcctattgag ggtctagatg ggaaaatcca     1860

cggcaacacc tgctccatgt gtgaagcctt cttccagcaa gaagcaaaag aaaaagaaag     1920

agctgaaccc agagcaaaag tcaaaagaga agctgaaaag gagacatgcg atgaatttcg     1980

gagacttttg caaaatggaa aacttttctg cacaagagaa aatgatcctg tgcgtggccc     2040

agatggcaag acccatggca acaagtgtgc catgtgtaag gcagtcttcc agaaagaaaa     2100

tgaggaaaga aagaggaaag aagaggaaga tcagagaaat gctgcaggac atggttccag     2160

tggtggtgga ggaggaaaca ctcaggacga atgtgctgag tatcgggaac aaatgaaaaa     2220

tggaagactc agctgtactc gggagagtga tcctgtacgt gatgctgatg gcaaatcgta     2280

caacaatcag tgtaccatgt gtaaagcaaa attggaaaga gaagcagaga gaaaaaatga     2340

gtattctcgc tccagatcaa atgggactgg atcagaatca gggaaggata catgtgatga     2400

gtttagaagc caaatgaaaa atggaaaact catctgcact cgagaaagtg accctgtccg     2460

gggtccagat ggcaagacac atggcaataa gtgtactatg tgtaaggaaa aactggaaag     2520

ggaagcagct gaaaaaaaaa agaaagagga tgaagacagg agcaatacag gagaaaggag     2580

caatacagga gaaaggagca atgacaaaga ggatctgtgt cgtgaatttc gaagcatgca     2640

gagaaatgga aagcttatct gcaccagaga aaataaccct gttcgaggcc catatggcaa     2700

gatgcacatc aataaatgtg ctatgtgtca gagcatcttt gatcgagaag ctaatgaaag     2760

aaaaaagaaa gatgaagaga aatcaagtag caagccctca aataatgcaa aggttattta     2820

ttaaaggata ccaaaataac cattttactt ttcaccttca gaattttgca ttcttctcca     2880

gctttgggaa taataaatat attaatatct taact                                2915


<210>  669
<211>  3906
<212>  DNA
<213>  homo sapiens

<400>  669
ggttggctgt ggccccgccc ccgagccctg gggtcggtgc ttgctgcctg cggctctcag       60

aagcctctgc tccaccgcgg cgagaggcat gggcacgtgg ctgccgaggg tggccgagct      120

ctgggaagaa aagcccgtgt gcctctgcat agcgtcgcta cagcgctgac tcggtgtgga      180

ttgattggaa aggtttgagg gagtacttgg gaagcatggt ggcacatgat gagactggag      240

gtctcctacc tattaaaagg accatacgag tcctagatgt caataaccag tccttcagag      300

aacaagagga gccaagcaat aaaagagttc gacctctggc tcgtgtcacg tccttggcaa      360

atttaatctc tcctgtaaga aatggagctg tcagacgttt tggtcaaaca atacagtcat      420

ttacccttcg tggtgaccac agatccccag cctctgccca gaagttttct agcaggtcaa      480

cagtcccaac acccgccaag agaaggagca gtgcactgtg gtcagagatg ctggacatca      540

ccatgaagga gtctctcacc accagggaga tcagacggca ggaggcaata tatgaaatgt      600

cccgaggtga acaggattta attgaggatc tcaaacttgc aagaaaggcc taccatgacc      660

ccatgttaaa gttgtccatc atgtcagaag aggaactcac acatatattt ggtgatctgg      720

actcttacat acctctgcat gaagatttgt tgacaagaat aggagaagca accaagcctg      780

atggaacagt ggagcagatt ggtcacattc tcgtgagctg gttaccgcgc ttgaatgcct      840

acagaggtta ctgtagtaac cagctggcag ccaaagctct tcttgatcaa aagaaacagg      900

atccaagagt ccaagacttc ctccagcgat gtctcgagtc tcccttcagt cgaaaactag      960

atctttggag tttcctagat atccctcgaa gtcgcctagt caaataccct ttactgttaa     1020

aagaaattct taaacacact ccaaaagagc accctgatgt tcagcttctg gaggatgcta     1080

tattgataat acagggagtc ctctctgata tcaacttgaa gaaaggtgaa tccgagtgcc     1140

agtattacat cgacaagctg gagtacctgg atgaaaagca gagggacccc agaatcgaag     1200

cgagcaaagt gctgctgtgc catggggagc tgcggagcaa gagtggacat aaactttaca     1260

ttttcctgtt tcaagacatc ttggttctga ctcggcccgt cacacggaac gaacggcact     1320

cttaccaggt ttaccggcag ccaatcccag tccaagagct agtcctagaa gacctgcagg     1380

atggagatgt gagaatggga ggctcctttc gaggagcttt cagtaactca gagaaagcta     1440

aaaatatctt tagaattcgc ttccatgacc cctctccagc ccagtctcac actctgcaag     1500

ccaatgacgt gttccacaag cagcagtggt tcaactgtat tcgagcggcc attgccccct     1560

tccagtcggc aggcagtcca cctgagctgc agggcctgcc ggagctgcac gaagagtgtg     1620

aggggaacca cccctctgcg aggaaactca cagcccagag gagggcatcc acagtttcca     1680

gtgttactca ggtagaagtt gatgaaaacg cttacagatg tggctctggc atgcagatgg     1740

cagaggacag caagagctta aagacacacc agacacagcc cggcatccga agagcgaggg     1800

acaaagccct ttctggtggc aaacggaaag agactttggt gtagagaagg ctctgtgtgt     1860

taactgatgg gagagactgt ttgtttataa atgtgtacag ttttgttttc tcgtaagggg     1920

agcatcatag ggttacttta taccagttgt aacattttca ttgtttttgg ttgttctttt     1980

ttcttttttt aatggcagct aaagatatac agattactgt taaattgcag tccttttttt     2040

tttaaagata ttttcttgaa ttatttagaa catggtaagc ctggtatttt ttaatcaaac     2100

aaaatattta tgaaatgggt tttctcttaa ttctggattc atcatggctt tctaatacca     2160

attgtaatat ttacaatatt caccaaaact tagaattttg caaatgctgg aattctgcca     2220

gtgtttcttt gctaagcctt gcatgcaaaa tttgaaattt taacattggc acccaaaacc     2280

tacatggaat gtatgtctgg agtatttcaa actttacatt gaaacataat ttccttggaa     2340

aacaaaccat aagcctgagg aggtttttat caactggaat gctttatatt agtttgtttt     2400

tcactgtaca ttcctcattt tacattcatt taacctgccg attatttaat ttttttattg     2460

taaagtagtt tttagcattt gcttttattt ttttactttg atgccttttc aaattggcat     2520

gtctttaaag tatttttctt cctgattaaa aatgtgtgtg tatgtgtgtg tgtgtgtgta     2580

tatatatata tatttttaaa tcacattaat tttaccaagt gaaaccaagc catactgttt     2640

ttgagccaat taagaaaatt gccattttta aagtgtagca tttcagggta aagacccatg     2700

aaatggcttg atgtattcta gactactgaa agaaaaccac ttcaaagatt ttgttgaaag     2760

ttttagtgtt gtctgaaatg caagagggaa ggtgattggt agtgagttaa aagaaaaaga     2820

gaggaaaaga gagtagtttt gtcttcaagt aaaatgtctg gttgtgccag acatttcaca     2880

agtgtgaaag gagataggag aagctcaact tgagggcgtg tagtaagttg tagaaggctc     2940

gaggggacgt ggacttattt gccttggttt gcaatacctg caaataatga gtttgaaaag     3000

aaacaatgaa atgtgttaaa aatttgacca tattagataa attttggtgg atttagtcat     3060

aagatggaaa aagactggtg aatcttttat tacaaaatgt ttctgttaaa atgggatcat     3120

catctttgaa aggggggagg aggagtaaaa gcccgattat aatggtgatc aattcaagtc     3180

agtgttgact attctgtgaa atatatttgg ccagtggaaa tgataatcag aaaagactgt     3240

aaatagatcc atccaaatga tttctctgta caaatgaatg atactattaa aaaaaaaaaa     3300

agcacacaca taatcaccct gaaggtttct tgcctggtgg ctatgttggg ggcatttggc     3360

aaaatatgct ggtgtggcaa aggaggtagt ggtaagcctc ataaaagtta gtaaaaattg     3420

tagttcaacc tttgaaatca ttgatgaatc agcgaaaggt aggtaagtct tgtgttagga     3480

aatcttttaa gaacatggtg taatcagaca cagcaattgt attgaaaata actgaacacc     3540

tgttactttc tggataggat agtaagggta gtagtggcaa aggatcctga ttaatttcag     3600

attttaatgt aagtacctca ggttcttgtc tttggaaatt cacattcata agtgtatatt     3660

acaccaatga ttgtgatctg caacaccaga aagcaagatt tctaatcatt tccagaggtg     3720

ttgtatagaa tagttattcc agagttacct tgatcagctt ctgaagttta agaagcaagt     3780

aatagttcaa gtgttgttaa tggaattatg ttttatttaa aaccgtatct tcttttggtt     3840

ccctcaaagg taaaaataag acccagaatc tgagtaaatc tattaaatga atgttcttca     3900

gaaata                                                                3906


<210>  670
<211>  3906
<212>  DNA
<213>  homo sapiens

<400>  670
ggttggctgt ggccccgccc ccgagccctg gggtcggtgc ttgctgcctg cggctctcag       60

aagcctctgc tccaccgcgg cgagaggcat gggcacgtgg ctgccgaggg tggccgagct      120

ctgggaagaa aagcccgtgt gcctctgcat agcgtcgcta cagcgctgac tcggtgtgga      180

ttgattggaa aggtttgagg gagtacttgg gaagcatggt ggcacatgat gagactggag      240

gtctcctacc tattaaaagg accatacgag tcctagatgt caataaccag tccttcagag      300

aacaagagga gccaagcaat aaaagagttc gacctctggc tcgtgtcacg tccttggcaa      360

atttaatctc tcctgtaaga aatggagctg tcagacgttt tggtcaaaca atacagtcat      420

ttacccttcg tggtgaccac agatccccag cctctgccca gaagttttct agcaggtcaa      480

cagtcccaac acccgccaag agaaggagca gtgcactgtg gtcagagatg ctggacatca      540

ccatgaagga gtctctcacc accagggaga tcagacggca ggaggcaata tatgaaatgt      600

cccgaggtga acaggattta attgaggatc tcaaacttgc aagaaaggcc taccatgacc      660

ccatgttaaa gttgtccatc atgtcagaag aggaactcac acatatattt ggtgatctgg      720

actcttacat acctctgcat gaagatttgt tgacaagaat aggagaagca accaagcctg      780

atggaacagt ggagcagatt ggtcacattc tcgtgagctg gttaccgcgc ttgaatgcct      840

acagaggtta ctgtagtaac cagctggcag ccaaagctct tcttgatcaa aagaaacagg      900

atccaagagt ccaagacttc ctccagcgat gtctcgagtc tcccttcagt cgaaaactag      960

atctttggag tttcctagat atccctcgaa gtcgcctagt caaataccct ttactgttaa     1020

aagaaattct taaacacact ccaaaagagc accctgatgt tcagcttctg gaggatgcta     1080

tattgataat acagggagtc ctctctgata tcaacttgaa gaaaggtgaa tccgagtgcc     1140

agtattacat cgacaagctg gagtacctgg atgaaaagca gagggacccc agaatcgaag     1200

cgagcaaagt gctgctgtgc catggggagc tgcggagcaa gagtggacat aaactttaca     1260

ttttcctgtt tcaagacatc ttggttctga ctcggcccgt cacacggaac gaacggcact     1320

cttaccaggt ttaccggcag ccaatcccag tccaagagct agtcctagaa gacctgcagg     1380

atggagatgt gagaatggga ggctcctttc gaggagcttt cagtaactca gagaaagcta     1440

aaaatatctt tagaattcgc ttccatgacc cctctccagc ccagtctcac actctgcaag     1500

ccaatgacgt gttccacaag cagcagtggt tcaactgtat tcgagcggcc attgccccct     1560

tccagtcggc aggcagtcca cctgagctgc agggcctgcc ggagctgcac gaagagtgtg     1620

aggggaacca cccctctgcg aggaaactca cagcccagag gagggcatcc acagtttcca     1680

gtgttactca ggtagaagtt gatgaaaacg cttacagatg tggctctggc atgcagatgg     1740

cagaggacag caagagctta aagacacacc agacacagcc cggcatccga agagcgaggg     1800

acaaagccct ttctggtggc aaacggaaag agactttggt gtagagaagg ctctgtgtgt     1860

taactgatgg gagagactgt ttgtttataa atgtgtacag ttttgttttc tcgtaagggg     1920

agcatcatag ggttacttta taccagttgt aacattttca ttgtttttgg ttgttctttt     1980

ttcttttttt aatggcagct aaagatatac agattactgt taaattgcag tccttttttt     2040

tttaaagata ttttcttgaa ttatttagaa catggtaagc ctggtatttt ttaatcaaac     2100

aaaatattta tgaaatgggt tttctcttaa ttctggattc atcatggctt tctaatacca     2160

attgtaatat ttacaatatt caccaaaact tagaattttg caaatgctgg aattctgcca     2220

gtgtttcttt gctaagcctt gcatgcaaaa tttgaaattt taacattggc acccaaaacc     2280

tacatggaat gtatgtctgg agtatttcaa actttacatt gaaacataat ttccttggaa     2340

aacaaaccat aagcctgagg aggtttttat caactggaat gctttatatt agtttgtttt     2400

tcactgtaca ttcctcattt tacattcatt taacctgccg attatttaat ttttttattg     2460

taaagtagtt tttagcattt gcttttattt ttttactttg atgccttttc aaattggcat     2520

gtctttaaag tatttttctt cctgattaaa aatgtgtgtg tatgtgtgtg tgtgtgtgta     2580

tatatatata tatttttaaa tcacattaat tttaccaagt gaaaccaagc catactgttt     2640

ttgagccaat taagaaaatt gccattttta aagtgtagca tttcagggta aagacccatg     2700

aaatggcttg atgtattcta gactactgaa agaaaaccac ttcaaagatt ttgttgaaag     2760

ttttagtgtt gtctgaaatg caagagggaa ggtgattggt agtgagttaa aagaaaaaga     2820

gaggaaaaga gagtagtttt gtcttcaagt aaaatgtctg gttgtgccag acatttcaca     2880

agtgtgaaag gagataggag aagctcaact tgagggcgtg tagtaagttg tagaaggctc     2940

gaggggacgt ggacttattt gccttggttt gcaatacctg caaataatga gtttgaaaag     3000

aaacaatgaa atgtgttaaa aatttgacca tattagataa attttggtgg atttagtcat     3060

aagatggaaa aagactggtg aatcttttat tacaaaatgt ttctgttaaa atgggatcat     3120

catctttgaa aggggggagg aggagtaaaa gcccgattat aatggtgatc aattcaagtc     3180

agtgttgact attctgtgaa atatatttgg ccagtggaaa tgataatcag aaaagactgt     3240

aaatagatcc atccaaatga tttctctgta caaatgaatg atactattaa aaaaaaaaaa     3300

agcacacaca taatcaccct gaaggtttct tgcctggtgg ctatgttggg ggcatttggc     3360

aaaatatgct ggtgtggcaa aggaggtagt ggtaagcctc ataaaagtta gtaaaaattg     3420

tagttcaacc tttgaaatca ttgatgaatc agcgaaaggt aggtaagtct tgtgttagga     3480

aatcttttaa gaacatggtg taatcagaca cagcaattgt attgaaaata actgaacacc     3540

tgttactttc tggataggat agtaagggta gtagtggcaa aggatcctga ttaatttcag     3600

attttaatgt aagtacctca ggttcttgtc tttggaaatt cacattcata agtgtatatt     3660

acaccaatga ttgtgatctg caacaccaga aagcaagatt tctaatcatt tccagaggtg     3720

ttgtatagaa tagttattcc agagttacct tgatcagctt ctgaagttta agaagcaagt     3780

aatagttcaa gtgttgttaa tggaattatg ttttatttaa aaccgtatct tcttttggtt     3840

ccctcaaagg taaaaataag acccagaatc tgagtaaatc tattaaatga atgttcttca     3900

gaaata                                                                3906


<210>  671
<211>  777
<212>  DNA
<213>  homo sapiens

<400>  671
gagccattga ttggtcgacg cccccagagg gttacaattc aaacgcgggc gggcgggccc       60

gcagtcctgc agttgcagtc gtgttctccg agttcctgtc tctctgccaa cgccgcccgg      120

atggcttccc aaaaccgcga cccagccgcc actagcgtcg ccgccgcccg taaaggagct      180

gagccgagcg ggggcgccgc ccggggtccg gtgggcaaaa ggctacagca ggagctgatg      240

accctcatgg tatatgaaga cctgaggtat aagctctcgc tagagttccc cagtggctac      300

ccttacaatg cgcccacagt gaagttcctc acgccctgct atcaccccaa cgtggacacc      360

cagggtaaca tatgcctgga catcctgaag gaaaagtggt ctgccctgta tgatgtcagg      420

accattctgc tctccatcca gagccttcta ggagaaccca acattgatag tcccttgaac      480

acacatgctg ccgagctctg gaaaaacccc acagctttta agaagtacct gcaagaaacc      540

tactcaaagc aggtcaccag ccaggagccc tgacccaggc tgcccagcct gtccttgtgt      600

cgtcttttta atttttcctt agatggtctg tcctttttgt gatttctgta taggactctt      660

tatcttgagc tgtggtattt ttgttttgtt tttgtctttt aaattaagcc tcggttgagc      720

ccttgtatat taaataaatg catttttgtc cttttttaga caaaaaaaaa aaaaaaa         777


<210>  672
<211>  901
<212>  DNA
<213>  homo sapiens

<400>  672
ccaggagctc agaccgctct ttgagactct cccgaaggag aatgggaggg taggggcgct       60

gccagactcc ttccctggtg ggcctagatg aagacgctca aggaccctcg tgacttggcc      120

gagacagggg aagggagaag ttgagtcggg caaggaagag atgctaaagc ctggggaatt      180

aagaacatgc cagaatcatc ccgagggagt ctggaattag ggagggtgag gactcgctag      240

gatcgtcctg tggatctggc tacagcagga gctgatgacc ctcatgatgt ctggcgataa      300

agggatttct gccttccctg aatcagacaa ccttttcaaa tgggtaggga ccatccatgg      360

agcagctgga acagtatatg aagacctgag gtataagctc tcgctagagt tccccagtgg      420

ctacccttac aatgcgccca cagtgaagtt cctcacgccc tgctatcacc ccaacgtgga      480

cacccagggt aacatatgcc tggacatcct gaaggaaaag tggtctgccc tgtatgatgt      540

caggaccatt ctgctctcca tccagagcct tctaggagaa cccaacattg atagtccctt      600

gaacacacat gctgccgagc tctggaaaaa ccccacagct tttaagaagt acctgcaaga      660

aacctactca aagcaggtca ccagccagga gccctgaccc aggctgccca gcctgtcctt      720

gtgtcgtctt tttaattttt ccttagatgg tctgtccttt ttgtgatttc tgtataggac      780

tctttatctt gagctgtggt atttttgttt tgtttttgtc ttttaaatta agcctcggtt      840

gagcccttgt atattaaata aatgcatttt tgtccttttt tagacaaaaa aaaaaaaaaa      900

a                                                                      901


<210>  673
<211>  2200
<212>  DNA
<213>  homo sapiens

<400>  673
agccaggctg ccaactcatt cgggagcccg gggcatgaac ggctacggct ccccctacct       60

gtacatgggc ggcccggtgt cgcagccgcc acgggcgccc ctgcagcgca cgcccaagtg      120

cgcgcgctgc cgcaaccatg gcgtcctgtc ctggctcaag ggccacaagc gttactgccg      180

cttcaaggac tgcacctgcg agaagtgcat cctcatcatc gagcggcagc gggtcatggc      240

tgcgcaggtg gcgctgcgcc ggcagcaggc caacgagagc ttggagagcc tcatccccga      300

ctcgctgcgc gctctgccag ggcccccgcc gccgggggac gccgtcgccg ccccgcagcc      360

gccgccagcc tctcagccgt cgcagccgca gccgccgcgc cctgctgccg agttggccgc      420

ggccgccgcg ctgcgttgga ctgccgagcc gcagcccggg gctctgcagg cgcagctcgc      480

caagccagat ttgactgaag aacgacttgg agacggcaag tcggcagaca atacagaggt      540

cttcagtgac aaagacactg accagaggag ttccccagat gtggcaaaga gtaagggctg      600

cttcacccct gagagccctg agatagtgtc cgtggaggaa gggggatacg ctgtccagaa      660

aaacggaggc aaccccgaga gccgccctga cagccccaag tgtcacgcgg agcagaatca      720

cctcctgatt gagggcccct cggggactgt ttctctgccc ttcagcttga aagccaacag      780

accgccgctt gaagtgttaa aaaagatatt ccccaaccag aagccaacgg tgcttgagct      840

catcctcaag ggctgtggcg gggacctggt gagcgccgtg gaagtccttc tgtccagccg      900

atcctcagtc acgggagcag agcgaacttc cgcagaacct gagagtctag cgttgccctc      960

caatgggcac atctttgaac acaccttgag ctcctacccc atctcgtctt ccaaatggtc     1020

tgtgggatca gcctttcgag tcccagacac gttgaggttt tctgccgact ctagcaacgt     1080

tgtccccagt cccttggctg ggcctctgca gccccctttc ccccagccac cccggtaccc     1140

gctgatgctg aggaatactt tggcgagaag ccagtcgagc ccctttttgc ccaatgatgt     1200

caccctgtgg aacaccatga cgctgcagca gcagtatcag ctgaggtccc agtatgtcag     1260

tcctttcccc agtaactcta ccagcgtctt cagaagctcg cccgtccttc ctgcccgcgc     1320

cacggaagac cctcggattt ccatccctga tgatgggtgt ccatttgtgt caaagcagtc     1380

catttacacc gaggacgact atgacgagag gtctgactcc tcagactcta gaacactcaa     1440

cacatcatct taaagtggtg ctggatgggt ggtggccagg tgacattttc tgtgcgtttt     1500

gaccctgagg catctgagga gaggccacat cttgtgtatg ccctttcctt ctgtttgaca     1560

aagtgactgt gcttgattct atacattagc aataaaaaca taacttattt aacttcttgc     1620

acttcactgg aaaatgccaa atagctctgt tctgtggctt tagtgctgaa tgtttattgt     1680

aaaagagagt ctaatgttaa gaatagtctt gggaaggctg ggtccgtgga agatttattt     1740

ggggatgtaa agctgaaggt cagccttgca cctaaaccca acctggaatg ttaaatgaaa     1800

taatatactt gaatgcaatt ttgtaaaagt ggattcctca ggatatgtga aacctaaagg     1860

aagtggttct gttgcaaatg gactataaac agggacatta tattcttaca ctaaaaatcc     1920

ttgcatttta aagagagatg cacttaagaa tagagtgaac tgctcatatg cttatttaag     1980

cttggacagt tttcagagac aaaccccatt aagaattact cttttcacat ggctgaatcg     2040

aaacatgtgt aatgtcaatg taaaaccaat cacagctgtg aactgcatga aatgtattgt     2100

gaaacgaaca caagattaag ctttgtcagg ttaatgtagc atgttaagga ctctagaaaa     2160

aaataaacta aggagacgag aaaaaaaaaa aaaaaaaaaa                           2200


<210>  674
<211>  4052
<212>  DNA
<213>  homo sapiens

<400>  674
aagtaagtgc gatggaacct tcaggttcca accgccgcca gggccgctcc gcccagtgga       60

gcctgtccgg cccccttgct gcccgctagc tcccgccggc tggcgcaagc tgtcggcgcc      120

ggggcactgc gggcggggtc ggagcctggc cttcctgacg ttgcagctgc cgtccccgca      180

cgttccggcc agggcctccc tcttagggcc gggcggtgcc cgtggctcag gctgcagagt      240

agaaagcaca aaaaccagcc tgattgtatc tggaaaaaac cattatgtta cagttgatag      300

gctcacccca aaatatgctt ttggggactg atttagcacc tgcatattct gcgtgaatct      360

ctttaattgg ttgcagttga gctaatggtg gagccaaaat gctattgccc tgtcttcatc      420

aacatttaat caagtgttgc ggagatagga acatgggaga gaaacaatct gggtaacatg      480

aaagtgatgc tggttgctaa gggaaggcaa cttgattctg tgggaagggc tgtagctgat      540

ccatccgttg tctagatttg agtatgagca cagtggaaga ggattctgac acagtaacag      600

tagaaactgt gaactctgtg actttgactc aggacacaga agggaatctc attcttcact      660

gccctcagaa tgaagcggat gaaatagact cagaagatag tattgaacct ccacataaaa      720

ggctttgttt gtcctctgag gatgatcaga gtattgatga ttctactcct tgcatatcag      780

ttgttgcact tccactttca gaaaatgatc agagctttga agtgaccatg actgcaacca      840

cagaagtagc agatgatgag gttactgagg ggactgtgac acagatacag attttgcaga      900

atgagcaact agatgaaata tctcccttgg gtaacgagga agtttcagca gttagccaag      960

catggtttac aactaaagaa gataaggatt ctctgactaa taaaggacat aaatggaagc     1020

aggggatgtg gtccaaggaa gaaattgata ttttgatgaa caatattgaa cgctatctta     1080

aggcacgcgg aataaaagat gctacagaaa tcatctttga gatgtcaaaa gacgaaagaa     1140

aagatttcta caggactata gcatggggtc tgaaccggcc tttgtttgca gtttatagaa     1200

gagtgcttcg catgtatgat gacagaaacc atgtgggaaa atatacacct gaagaaattg     1260

agaagctcaa ggagctccgg ataaagcatg gcaatgactg ggcaacaata ggggcggcgc     1320

taggaagaag tgcatcttct gtcaaagatc ggtgccgact gatgaaggat acttgcaaca     1380

cagggaagtg gacagaagaa gaagaaaaga gacttgcaga agtggttcat gagttgacaa     1440

gcactgagcc aggtgacata gtcacacagg gtgtgtcttg ggcagctgtg gctgaacgag     1500

tcggtacccg ctcagaaaag caatgtcgtt ctaaatggct caactacctg aattggaaac     1560

agagtggggg tactgaatgg accaaggaag atgaaatcaa tctcatcctc aggatagcag     1620

aacttgatgt agctgatgaa aatgacatta actgggatct gttagctgag ggatggagta     1680

gtgtccgttc accacaatgg ctacgaagta aatggtggac catcaaaagg caaattgcaa     1740

accataagga tgtttcgttc cctgtcttaa taaaaggtct taaacagtta catgagaacc     1800

aaaaaaacaa cccaacgctt ttggagaata aatcaggatc tggagttcca aacagtaata     1860

ccaattccag tgtgcagcat gttcagataa gagttgcccg cttggaagat aatacagcca     1920

tctcttctag ccccatggca gcattgcaga ttccagtcca gatcacccat gtttcttcag     1980

cagactctcc tgctaccgtt gactcagaaa caataacact aaacagtgga acactacaga     2040

catttgagat tcttccctct ttccatctac agcccactgg cactccaggc acctacctac     2100

ttcaaacaag ctcaagccaa ggccttcccc taactctgac tgctagtccc acagtaaccc     2160

tgacagctgc tgctcctgct tctcctgaac agattattgt tcatgcttta tccccagaac     2220

atttgttgaa cacaagtgat aatgttacag tgcagtgtca cacaccaaga gtcatcattc     2280

agactgttgc cacagaggac atcacttctt ccatatccca agcagaactg acagtcgata     2340

gtgatattca gtcatctgat tttcctgagc ctccagacgc cctagaagca gacactttcc     2400

cagatgaaat tcatcaccct aagatgactg tggagccatc atttaatgat gctcatgtat     2460

ccaaattcag tgaccaaaat agcacagaac tgatgaatag tgttatggtc agaacagaag     2520

aagaaatctc tgacaccgac cttaaacaag aggaatcacc ctctgattta gccagtgctt     2580

atgttactga gggtttagag tctcccacta tagaagaaca agttgatcaa acaattgatg     2640

atgaaacaat acttatcgtt ccttcaccac atggctttat ccaggcatct gatgttatag     2700

atactgaatc tgtcttgcct ttgacaacac taacagatcc catactccaa catcatcagg     2760

aagaatcaaa tatcattgga tcatccttgg gcagtcctgt ttcagaagat tcaaaggatg     2820

tcgaagattt ggtaaactgt cattagaata attcttagaa ataggcagtt caagcaaaga     2880

aggcacactg ttaattacaa cctcttcaaa gaaataggag caacccccaa gaggcttaat     2940

ttaccaattt aaatagccac agtccttaag ccacacacat tgttgctgct atgacttttt     3000

acctccttta aacacatcat ctgaggttga gttttatgac agtatgtagt tgagtggagg     3060

ctgggagttt taagcataaa tccctgttta gtgttacatg ggaataagga atttcattca     3120

cttcagccac taagaaaagt ttagaatcac gaaagcttaa ctgctgtggt ttaaagtaca     3180

gtttctctaa agatcagaca tggcactgtc tcctctcaag cctggttgta gttcagatga     3240

gtcttttcaa catggtcttc aacatggtct agagcttacc agtgatcttc tgatcttcaa     3300

gaagactaag tttgagactt gaccagcata caagtataga gacctaggag gtggtcttgt     3360

ggtggtacat ttggttaacc cattgctggc agtgggagct gatttaggca gggtaaacag     3420

gaaagcatta aaagttaaaa ttcactacag gttttttgtt acttttaaag ggaatatgga     3480

taagcatagt aacaaaaccc accagaatct aagcagtttt caccccctca gaaaccactg     3540

tcattagttt acaaagttag cactttgaag taaaactaaa tgaggaagga agtaatgtta     3600

cctatccttg ataccatgac catttattag atgttttgct atataaatta ccgagagaat     3660

agtttgtcat ccacttagtg tgttagctgg tggggtacaa tataacctct catctcaggc     3720

tattttaaaa aaacaatatt tgcttctata acaaaaggaa acaaatctaa gaatcattcc     3780

tgtactacag aagggttaag gcaaaggtag ccttttgggc tttttaatga atatgacccc     3840

tatagaaaag tcaagaaaaa aaaacccttg tataaattat tttatttatt attgtaatta     3900

gatcttcaca aagttgtctt ttcactgtgt tttgtcaacg tgaaattaaa ttgtagttat     3960

aagcaaaagt tggttgccta gggaacaatt gtatattcag tttaacagaa ataaaagaat     4020

atttgtctta agatgcaaaa aaaaaaaaaa aa                                   4052


<210>  675
<211>  3095
<212>  DNA
<213>  homo sapiens

<400>  675
caaccccacc cagccctcag acccttccag ctgccgctgt cgtctttgct tcagccgcag       60

tcgccactgg ctgcctgagg tgctcttaca gcctgttcca agtgtggctt aatccgtctc      120

caccaccaga tctttctccg tggattcctc tgctaagacc gctgccatgc cagtgacggt      180

aacccgcacc accatcacaa ccaccacgac gtcatcttcg ggcctggggt cccccatgat      240

cgtggggtcc cctcgggccc tgacacagcc cctgggtctc cttcgcctgc tgcagctggt      300

gtctacctgc gtggccttct cgctggtggc tagcgtgggc gcctggacgg ggtccatggg      360

caactggtcc atgttcacct ggtgcttctg cttctccgtg accctgatca tcctcatcgt      420

ggagctgtgc gggctccagg cccgcttccc cctgtcttgg cgcaacttcc ccatcacctt      480

cgcctgctat gcggccctct tctgcctctc ggcctccatc atctacccca ccacctatgt      540

ccagttcctg tcccacggcc gttcgcggga ccacgccatc gccgccacct tcttctcctg      600

catcgcgtgt gtggcttacg ccaccgaagt ggcctggacc cgggcccggc ccggcgagat      660

cactggctat atggccaccg tacccgggct gctgaaggtg ctggagacct tcgttgcctg      720

catcatcttc gcgttcatca gcgaccccaa cctgtaccag caccagccgg ccctggagtg      780

gtgcgtggcg gtgtacgcca tctgcttcat cctagcggcc atcgccatcc tgctgaacct      840

gggggagtgc accaacgtgc tacccatccc cttccccagc ttcctgtcgg ggctggcctt      900

gctgtctgtc ctcctctatg ccaccgccct tgttctctgg cccctctacc agttcgatga      960

gaagtatggc ggccagcctc ggcgctcgag agatgtaagc tgcagccgca gccatgccta     1020

ctacgtgtgt gcctgggacc gccgactggc tgtggccatc ctgacggcca tcaacctact     1080

ggcgtatgtg gctgacctgg tgcactctgc ccacctggtt tttgtcaagg tctaagactc     1140

tcccaagagg ctcccgttcc ctctccaacc tctttgttct tcttgcccga gttttcttta     1200

tggagtactt ctttcctccg cctttcctct gttttcctct tcctgtctcc cctccctccc     1260

acctttttct ttccttccca attccttgca ctctaaccag ttcttggatg catcttcttc     1320

cttccctttc ctcttgctgt ttccttcctg tgttgttttg ttgcccacat cctgttttca     1380

cccctgagct gtttctcttt ttcttttctt tttttttttt tttttttttt aagacggatt     1440

ctcactctgt ggcccaggct ggagtgcagt ggtgcgatct cgactcactg caacccccgc     1500

ctcctgggtt caagcgattc tcctgcccca gcctcccaag tagctgggag gacaggtgtg     1560

agctgccgca cccagcctgt ttctcttttt ccactcttct tttttctcat ctcttttctg     1620

ggttgcctgt cggctttctt atctgcctgt tttgcaagca ccttctcctg tgtccttggg     1680

agccctgaga cttctttctc tccttgcctc cacccacctc caaaggtgct gagctcacat     1740

ccacacccct tgcagccgtc catgccacag ccccccaagg ggccccattg ccaaagcatg     1800

cctgcccacc ctcgctgtgc cttagtcagt gtgtacgtgt gtgtgtgtgt gtgtgtgtgt     1860

gtgtgtgttt ggggggtggg gggtgggtag ctggggattg ggccctcttt ctcccagtgg     1920

aggaaggtgt gcagtgtact tcccctttaa attaaaaaac atatatatat atatatttgg     1980

aggtcagtaa tttccaatgg gcgggaggct ttaagcaccg accctgggtc cctaggcccc     2040

gcctggcact cagccttgcc agagattggc tccagaattt ttgccaggct tacagaacac     2100

ccactgccta gaggccatct taaaggaagc aggggctgga tgcctttcat cccaactatt     2160

ctctgtggta tcaaaaagaa aaaaaaaaaa aaagaaggag tcggggccgg gcgtggtggc     2220

tcacgcctgt aatcccagca ctttgggaga ccaagtcagg caatcatctg aagtcaggag     2280

ttcaagacca gcctggccaa catggtgaaa gcatgtctct attaaaaata caaaaattag     2340

ccgggcgtgg tggcgggcgc ctgtaatccc aggtatttgg ggggactgag acaggagaat     2400

cccttcaacc cgggaggtgg aggttgcagt aagtcaagat ggcaccactg tgctccagcc     2460

tgggggacag agcgagactc catctcaaaa aaaaaaagga atcggacgaa gaaccacagg     2520

atgttgaaga caactgtctg aagtatttgt gagggacagc gatgtggccc tctgtgttaa     2580

gaataacgtg tcctgctttg gcagagagaa gaaaatagcc actgcccgct ttcaaggcaa     2640

gatcgacctt ttctgttttg ttttgttttt ctttcttttt cctggccatg aggacaaaaa     2700

ttactgagtg gcccttaaag agggaagttt gttttcagct gttctctttt gcccgtaggt     2760

gggagggtgg ggattgctgc gtcctagcta gaggaatggc tttgcttgaa tgtgtagtgc     2820

acacgcacgg gtgtttctgt gtgctagttg cttcttgctg ctgcttcctg cttgtctggg     2880

actcacatac ataacgtgat atatatatat atatatataa atgtataaat atatatttta     2940

ttttttttta aatccctgga gcttctggtt cctatcagtt cctgttgtta atcgtagaac     3000

cgttgtccct tcccccattc ccgtatccat catgttcttt ttcttttaaa tatcaatata     3060

aaggtaaaag aaaaaaaaaa aaaaaaaaaa aaaaa                                3095


<210>  676
<211>  3095
<212>  DNA
<213>  homo sapiens

<400>  676
caaccccacc cagccctcag acccttccag ctgccgctgt cgtctttgct tcagccgcag       60

tcgccactgg ctgcctgagg tgctcttaca gcctgttcca agtgtggctt aatccgtctc      120

caccaccaga tctttctccg tggattcctc tgctaagacc gctgccatgc cagtgacggt      180

aacccgcacc accatcacaa ccaccacgac gtcatcttcg ggcctggggt cccccatgat      240

cgtggggtcc cctcgggccc tgacacagcc cctgggtctc cttcgcctgc tgcagctggt      300

gtctacctgc gtggccttct cgctggtggc tagcgtgggc gcctggacgg ggtccatggg      360

caactggtcc atgttcacct ggtgcttctg cttctccgtg accctgatca tcctcatcgt      420

ggagctgtgc gggctccagg cccgcttccc cctgtcttgg cgcaacttcc ccatcacctt      480

cgcctgctat gcggccctct tctgcctctc ggcctccatc atctacccca ccacctatgt      540

ccagttcctg tcccacggcc gttcgcggga ccacgccatc gccgccacct tcttctcctg      600

catcgcgtgt gtggcttacg ccaccgaagt ggcctggacc cgggcccggc ccggcgagat      660

cactggctat atggccaccg tacccgggct gctgaaggtg ctggagacct tcgttgcctg      720

catcatcttc gcgttcatca gcgaccccaa cctgtaccag caccagccgg ccctggagtg      780

gtgcgtggcg gtgtacgcca tctgcttcat cctagcggcc atcgccatcc tgctgaacct      840

gggggagtgc accaacgtgc tacccatccc cttccccagc ttcctgtcgg ggctggcctt      900

gctgtctgtc ctcctctatg ccaccgccct tgttctctgg cccctctacc agttcgatga      960

gaagtatggc ggccagcctc ggcgctcgag agatgtaagc tgcagccgca gccatgccta     1020

ctacgtgtgt gcctgggacc gccgactggc tgtggccatc ctgacggcca tcaacctact     1080

ggcgtatgtg gctgacctgg tgcactctgc ccacctggtt tttgtcaagg tctaagactc     1140

tcccaagagg ctcccgttcc ctctccaacc tctttgttct tcttgcccga gttttcttta     1200

tggagtactt ctttcctccg cctttcctct gttttcctct tcctgtctcc cctccctccc     1260

acctttttct ttccttccca attccttgca ctctaaccag ttcttggatg catcttcttc     1320

cttccctttc ctcttgctgt ttccttcctg tgttgttttg ttgcccacat cctgttttca     1380

cccctgagct gtttctcttt ttcttttctt tttttttttt tttttttttt aagacggatt     1440

ctcactctgt ggcccaggct ggagtgcagt ggtgcgatct cgactcactg caacccccgc     1500

ctcctgggtt caagcgattc tcctgcccca gcctcccaag tagctgggag gacaggtgtg     1560

agctgccgca cccagcctgt ttctcttttt ccactcttct tttttctcat ctcttttctg     1620

ggttgcctgt cggctttctt atctgcctgt tttgcaagca ccttctcctg tgtccttggg     1680

agccctgaga cttctttctc tccttgcctc cacccacctc caaaggtgct gagctcacat     1740

ccacacccct tgcagccgtc catgccacag ccccccaagg ggccccattg ccaaagcatg     1800

cctgcccacc ctcgctgtgc cttagtcagt gtgtacgtgt gtgtgtgtgt gtgtgtgtgt     1860

gtgtgtgttt ggggggtggg gggtgggtag ctggggattg ggccctcttt ctcccagtgg     1920

aggaaggtgt gcagtgtact tcccctttaa attaaaaaac atatatatat atatatttgg     1980

aggtcagtaa tttccaatgg gcgggaggct ttaagcaccg accctgggtc cctaggcccc     2040

gcctggcact cagccttgcc agagattggc tccagaattt ttgccaggct tacagaacac     2100

ccactgccta gaggccatct taaaggaagc aggggctgga tgcctttcat cccaactatt     2160

ctctgtggta tcaaaaagaa aaaaaaaaaa aaagaaggag tcggggccgg gcgtggtggc     2220

tcacgcctgt aatcccagca ctttgggaga ccaagtcagg caatcatctg aagtcaggag     2280

ttcaagacca gcctggccaa catggtgaaa gcatgtctct attaaaaata caaaaattag     2340

ccgggcgtgg tggcgggcgc ctgtaatccc aggtatttgg ggggactgag acaggagaat     2400

cccttcaacc cgggaggtgg aggttgcagt aagtcaagat ggcaccactg tgctccagcc     2460

tgggggacag agcgagactc catctcaaaa aaaaaaagga atcggacgaa gaaccacagg     2520

atgttgaaga caactgtctg aagtatttgt gagggacagc gatgtggccc tctgtgttaa     2580

gaataacgtg tcctgctttg gcagagagaa gaaaatagcc actgcccgct ttcaaggcaa     2640

gatcgacctt ttctgttttg ttttgttttt ctttcttttt cctggccatg aggacaaaaa     2700

ttactgagtg gcccttaaag agggaagttt gttttcagct gttctctttt gcccgtaggt     2760

gggagggtgg ggattgctgc gtcctagcta gaggaatggc tttgcttgaa tgtgtagtgc     2820

acacgcacgg gtgtttctgt gtgctagttg cttcttgctg ctgcttcctg cttgtctggg     2880

actcacatac ataacgtgat atatatatat atatatataa atgtataaat atatatttta     2940

ttttttttta aatccctgga gcttctggtt cctatcagtt cctgttgtta atcgtagaac     3000

cgttgtccct tcccccattc ccgtatccat catgttcttt ttcttttaaa tatcaatata     3060

aaggtaaaag aaaaaaaaaa aaaaaaaaaa aaaaa                                3095


<210>  677
<211>  2554
<212>  DNA
<213>  homo sapiens

<400>  677
gagccgagat cgcgccaccg ccctccagcc tgggcgacag agcaagactc tgtctcaaaa       60

aaaaaaaaaa aaagagcaaa ttttttttcc aaggtgatag ggagagtccg tggctgatgt      120

ctgcactgac cagacgcccc tagggggcca gcgagggcgg gtcccaggtg cagcggatgc      180

agaggagaga ggcccgggcg cggcgcgggg gatggtgcga tcccgggccc gagggcatca      240

gacggcggct gattagctcc ggtttgcatc acccggaccg ggggattagc tccggtttgc      300

atcacccgga ccgggggatt agctccggtt tgcatcaccc ggaccggggg ccgggcgcgc      360

acgagactcg cagcggaagt ggaggcggct ccgcgcgcgt ccgctgctag gacccgggca      420

gggctggagc tgggctggga tcccgagctc ggcagcagcg cagcgggccg gcccacctgc      480

tggtgccctg gaggctctga gccccggcgg cgcccgggcc cacgcggaac gacggggcga      540

gatgcgagcc acccctctgg ctgctcctgc gggttccctg tccaggaaga agcggttgga      600

gttggatgac aacttagata ccgagcgtcc cgtccagaaa cgagctcgaa gtgggcccca      660

gcccagactg cccccctgcc tgttgcccct gagcccacct actgctccag atcgtgcaac      720

tgctgtggcc actgcctccc gtcttgggcc ctatgtcctc ctggagcccg aggagggcgg      780

gcgggcctac caggccctgc actgccctac aggcactgag tatacctgca aggtgtaccc      840

cgtccaggaa gccctggccg tgctggagcc ctatgcgcgg ctgcccccgc acaagcatgt      900

ggctcggccc actgaggtcc tggctggtac ccagctcctc tacgcctttt tcactcggac      960

ccatggggac atgcacagcc tggtgcgaag ccgccaccgt atccctgagc ctgaggctgc     1020

cgtgctcttc cgccagatgg ccaccgccct ggcgcactgt caccagcacg gtctggtcct     1080

gcgtgatctc aagctgtgtc gctttgtctt cgctgaccgt gagaggaaga agctggtgct     1140

ggagaacctg gaggactcct gcgtgctgac tgggccagat gattccctgt gggacaagca     1200

cgcgtgccca gcctacgtgg gacctgagat actcagctca cgggcctcat actcgggcaa     1260

ggcagccgat gtctggagcc tgggcgtggc gctcttcacc atgctggccg gccactaccc     1320

cttccaggac tcggagcctg tcctgctctt cggcaagatc cgccgcgggg cctacgcctt     1380

gcctgcaggc ctctcggccc ctgcccgctg tctggttcgc tgcctccttc gtcgggagcc     1440

agctgaacgg ctcacagcca caggcatcct cctgcacccc tggctgcgac aggacccgat     1500

gcccttagcc ccaacccgat cccatctctg ggaggctgcc caggtggtcc ctgatggact     1560

ggggctggac gaagccaggg aagaggaggg agacagagaa gtggttctgt atggctagga     1620

ccaccctact acacgctcag ctgccaacag tggattgagt ttgggggtag ctccaagcct     1680

tctcctgcct ctgaactgag ccaaaccttc agtgccttcc agaagggaga aaggcagaag     1740

cctgtgtgga gtgtgctgtg tacacatctg ctttgttcca cacacatgca gttcctgctt     1800

gggtgcttat caggtgccaa gccctgttct cggtgctggg agtacagcag tgagcaaagg     1860

agacaatatt ccctgctcac agagatgaca aactggcatc cttgagctga caacactttt     1920

ccatgaccat aggtcactgt ctacactggg tacactttgt accagtgtcg gcctccactg     1980

atgctggtgc tcaggcacct ctgtccaagg acaatccctt tcacaaacaa accagctgcc     2040

tttgtatctt gtaccttttc agagaaaggg aggtatccct gtgccaaagg ctccaggcct     2100

ctcccctgca actcaggacc caagcccagc tcactctggg aactgtgttc ccagcatctc     2160

tgtcctcttg attaagagat tctccttcca ggcctaagcc tgggatttgg gccagagata     2220

agaatccaaa ctatgaggct agttcttgtc taactcaaga ctgttctgga atgagggtcc     2280

aggcctgtca accatggggc ttctgacctg agcaccaagg ttgagggaca ggattaggca     2340

gggtctgtcc tgtggccacc tggaaagtcc caggtgggac tcttctgggg acacttgggg     2400

tccacaatcc caggtccata ctctaggttt tggataccat gagtatgtat gtttacctgt     2460

gcctaataaa ggagaattat gaaataaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa                                 2554


<210>  678
<211>  3296
<212>  DNA
<213>  homo sapiens

<400>  678
taagaaacga cacacagatt aggcagtgct actcttctta aatctctcat ttgtttccta       60

ggttccctgg ttgtgaaaat acatgagata aatcatgaag gccactatca tcctccttct      120

gcttgcacaa gtttcctggg ctggaccgtt tcaacagaga ggcttatttg actttatgct      180

agaagatgag gcttctggga taggcccaga agttcctgat gaccgcgact tcgagccctc      240

cctaggccca gtgtgcccct tccgctgtca atgccatctt cgagtggtcc agtgttctga      300

tttgggttgt ctaccttcat aacaacaata tctctgtagt tggatcaagt gacttctgcc      360

cacctggaca caacaccaaa aaggcttctt attcgggtgt gagtcttttc agcaacccgg      420

tccagtactg ggagatacag ccatccacct tcagatgtgt ctacgtgcgc tctgccattc      480

aactcggaaa ctataagtaa ttctcaagaa agccctcatt tttataacct ggcaaaatct      540

tgttaatgtc attgctaaaa aataaataaa agctagatac tggaaaccta actgcaatgt      600

ggatgtttta cccacatgac ttattatgca taaagccaaa tttccagttt aagtaattgc      660

ctacaataaa aagaaatttt gcctgccatt ttcagaatca tcttttgaag ctttctgttg      720

atgttaactg agctactaga gatattctta tttcactaaa tgtaaaattt ggagtaaata      780

tatatgtcaa tatttagtaa agcttttctt ttttaatttc caggaaaaaa taaaaagagt      840

atgagtcttc tgtaattcat tgagcagtta gctcatttga gataaagtca aatgccaaac      900

actagctctg tattaatccc catcattact ggtaaagcct catttgaatg tgtgaattca      960

atacaggcta tgtaaaattt ttactaatgt cattattttg aaaaaataaa tttaaaaata     1020

cattcaaaat tactattgta tacaagctta attgttaata ttccctaaac acaattttat     1080

gaagggagaa gacattggtt tgttgacaat aacagtacat cttttcaagt tctcagctat     1140

ttcttctacc tctccctatc ttacatttga gtatggtaac ttatgtcatc tatgttgaat     1200

gtaagcttat aaagcacaaa gcatacattt cctgactggt ctagagaact gatgtttcaa     1260

tttacccctc tgctaaataa atattaaaac tatcatgtga cttcatgtaa tcaggctgaa     1320

catttctaca attactagat gtattagacg taagtatttt ctttagttaa accacccatg     1380

ttagaaatgt tttctgtaga atttataaac aactatcaat gcagacaatt taataagcct     1440

ggggatgatt tacttacagt aaacatttat caaattgtac atttgtgcta tcaacaatta     1500

ataagcaaat atgtgaaaat agtttctgtc ttctatgaag ttagatattt gatggttaaa     1560

acccctataa atcatagttt catatgggaa aaaataattg aaatacagtg taaatttaaa     1620

taatttatta agtatagcaa ataattgaaa tatggtggac taaattttgt catagaaata     1680

tgtgcaagtt atagtagtgg ctcacatgag aggtaatcaa ttctgctaat agtagcagaa     1740

tgagtgcagt ggaacatgaa aaacttgagg agataacagt tgaggtgggt ttccatagat     1800

gcataatagt tcaagagcaa gatttggtgg ggaggcacta ttcaagacag ggactaagtt     1860

caaaatccaa gacgtatgct gggacacacc tctgacaggt tggcataaag gaggcttaat     1920

caaactattt ttcttcttct gaaacagaag caataatttt catttacatt tgacatatcc     1980

cgaggtaata ttaacattag ggaaagttac tcttttccat ctttccacat tcttgcagga     2040

ccataaaatc tgaattttcc agtattttta ataagaggga agaaacctct ctttttcttc     2100

tctttttcat ctcccaagag atcctcctct catgactaca gttgaatagg tggtttctat     2160

tggaagacat tcaggaattc aaggtgcatg tccataaatg gacttttttt gttgttgttc     2220

agagctggac cttgaatgat gcatccttct ctctgttgta accatgaata atgcaccctt     2280

catgctatag cctttaacga ttcacccttc ttattgtaac cttgaatgat tcacccttta     2340

tggtgtagcc ttgagtgacg cacccttcat gttgtagcct tcaatgatgc acactccatg     2400

ttatagcctt gaatgatata ccctttatgc tgcagccttt ctcttatggg gaaaagcctg     2460

cagatatcct gctgcttaac tgacaagtgt ggtgagaaat aagtagaaat ctaaagaggg     2520

gaagaccatt ttggacactt atctgcaagg cagatccaac acacttttcc agtagtcaag     2580

ctacttctaa ttttgttcag tatcaaaatg agaaacaggc ctgattctcc agcactcttg     2640

tcaacacaac ttccccccat atttatatat atacacacac atatatatct ttatatatat     2700

acacacatat atatctttat atatatatat ttatatatat atctttttgc atatatacat     2760

atatatgtat ctttatttcc tttgaaataa agataaatat agctgatttc tttggcttcg     2820

acacttacta tttgcatgac taagggaagc tagttaacct ttctgtgact catttccttg     2880

tccataaaat gggaatatta attgtacatg tcttatggat tggtgtgtga attcagttag     2940

cgagtgtaga atataactta tagatcaaag tagagtaaat ggaaagggct caactatggt     3000

gttgctactg ccattgttat tacaggcaca cagttcgagc tataatcatt tcaagggaaa     3060

ttcttatgtg tcagttctgg atcgaggtct gagattctgc atttcaaaca aacttccagg     3120

aatgctgctg cttcttggtc cacacttgga gaaataagtc agcagagagt cctctcgttt     3180

cctattgtac catgtctgtc ttttgtctcc tgcttattgg cctctgtaag gaactcacag     3240

ctgctataat aaagtaccaa aaactgggtg gcttaaaaca aaaaaaaaaa aaaaaa         3296


<210>  679
<211>  8994
<212>  DNA
<213>  homo sapiens

<400>  679
accatagagt gaatctcaga acaggaagcg gaggcataag cagagaggat tctggaaagg       60

tctctttgtt ttcttatcca cagagaaaga aagaaaaaaa attgtaacta atttgtaaac      120

ctctgtggtc aaaaaaaaaa aaaaaaaaaa aagctgaaca gctgcagagg aagacacgtt      180

ataccctaac catcttggat gctgggcttt gttatgctgt aattcataag gctctgtttt      240

atcagagatt atggagcaag aaaactgaag ccaagccaca tcaaggtttg acagggatga      300

gatacctgtc aaggattcat agtagagtgg cttactggga aaggagcaaa gaatctcttc      360

tagggatatt gtaagaataa atgagataat tcacagaagg gacctggagc ttttccggaa      420

aaaggtgctg tgactatcta aggtaattcg tatgcaagaa gctacacgta attaaatgtg      480

caggatgaaa agatggcaca ggcactgttg gtacccccag gacctgaaag cttccgcctt      540

tttactagag aatctcttgc tgctatcgaa aaacgtgctg cagaagagaa agccaagaag      600

cccaaaaagg aacaagataa tgatgatgag aacaaaccaa agccaaatag tgacttggaa      660

gctggaaaga accttccatt tatttatgga gacattcctc cagagatggt gtcagagccc      720

ctggaggacc tggatcccta ctatatcaat aagaaaactt ttatagtaat gaataaagga      780

aaggcaattt tccgattcag tgccacctct gccttgtata ttttaactcc actaaaccct      840

gttaggaaaa ttgctatcaa gattttggta cattctttat tcagcatgct tatcatgtgc      900

actattttga ccaactgtgt atttatgacc ttgagcaacc ctcctgactg gacaaagaat      960

gtagagtaca cattcactgg aatctatacc tttgagtcac ttataaaaat cttggcaaga     1020

gggttttgct tagaagattt tacgtttctt cgtgatccat ggaactggct ggatttcagt     1080

gtcattgtga tggcatatgt gacagagttt gtggacctgg gcaatgtctc agcgttgaga     1140

acattcagag ttctccgagc actgaaaaca atttcagtca ttccaggttt aaagaccatt     1200

gtgggggccc tgatccagtc ggtaaagaag ctttctgatg tgatgatcct gactgtgttc     1260

tgtctgagcg tgtttgctct cattgggctg cagctgttca tgggcaatct gaggaataaa     1320

tgtttgcagt ggcccccaag cgattctgct tttgaaacca acaccacttc ctactttaat     1380

ggcacaatgg attcaaatgg gacatttgtt aatgtaacaa tgagcacatt taactggaag     1440

gattacattg gagatgacag tcacttttat gttttggatg ggcaaaaaga ccctttactc     1500

tgtggaaatg gctcagatgc aggccagtgt ccagaaggat acatctgtgt gaaggctggt     1560

cgaaacccca actatggcta cacaagcttt gacaccttta gctgggcttt cctgtctcta     1620

tttcgactca tgactcaaga ctactgggaa aatctttacc agttgacatt acgtgctgct     1680

gggaaaacat acatgatatt ttttgtcctg gtcattttct tgggctcatt ttatttggtg     1740

aatttgatcc tggctgtggt ggccatggcc tatgaggagc agaatcaggc caccttggaa     1800

gaagcagaac aaaaagaggc cgaatttcag cagatgctcg aacagcttaa aaagcaacag     1860

gaagaagctc aggcagttgc ggcagcatca gctgcttcaa gagatttcag tggaataggt     1920

gggttaggag agctgttgga aagttcttca gaagcatcaa agttgagttc caaaagtgct     1980

aaagaatgga ggaaccgaag gaagaaaaga agacagagag agcaccttga aggaaacaac     2040

aaaggagaga gagacagctt tcccaaatcc gaatctgaag acagcgtcaa aagaagcagc     2100

ttccttttct ccatggatgg aaacagactg accagtgaca aaaaattctg ctcccctcat     2160

cagtctctct tgagtatccg tggctccctg ttttccccaa gacgcaatag caaaacaagc     2220

attttcagtt tcagaggtcg ggcaaaggat gttggatctg aaaatgactt tgctgatgat     2280

gaacacagca catttgaaga cagcgaaagc aggagagact cactgtttgt gccgcacaga     2340

catggagagc gacgcaacag taacggcacc accacagaaa cggaagtcag aaagagaagg     2400

ttaagctctt accagatttc aatggagatg ctggaggatt cctctggaag gcaaagagcc     2460

gtgagcatag ccagcattct gaccaacaca atggaagaac ttgaagaatc tagacagaaa     2520

tgtccgccat gctggtatag atttgccaat gtgttcttga tctgggactg ctgtgatgca     2580

tggttaaaag taaaacatct tgtgaattta attgttatgg atccatttgt tgatcttgcc     2640

atcactattt gcattgtctt aaataccctc tttatggcca tggagcacta ccccatgact     2700

gagcaattca gtagtgtgtt gactgtagga aacctggtct ttactgggat tttcacagca     2760

gaaatggttc tcaagatcat tgccatggat ccttattact atttccaaga aggctggaat     2820

atctttgatg gaattattgt cagcctcagt ttaatggagc ttggtctgtc aaatgtggag     2880

ggattgtctg tactgcgatc attcagactg cttagagttt tcaagttggc aaaatcctgg     2940

cccacactaa atatgctaat taagatcatt ggcaattctg tgggggctct aggaaacctc     3000

accttggtgt tggccatcat cgtcttcatt tttgctgtgg tcggcatgca gctctttggt     3060

aagagctaca aagaatgtgt ctgcaagatc aatgatgact gtacgctccc acggtggcac     3120

atgaacgact tcttccactc cttcctgatt gtgttccgcg tgctgtgtgg agagtggata     3180

gagaccatgt gggactgtat ggaggtcgct ggccaaacca tgtgccttat tgttttcatg     3240

ttggtcatgg tcattggaaa ccttgtggtt ctgaacctct ttctggcctt attgttgagt     3300

tcatttagct cagacaacct tgctgctact gatgatgaca atgaaatgaa taatctgcag     3360

attgcagtag gaagaatgca aaagggaatt gattatgtga aaaataagat gcgggagtgt     3420

ttccaaaaag ccttttttag aaagccaaaa gttatagaaa tccatgaagg caataagata     3480

gacagctgca tgtccaataa tactggaatt gaaataagca aagagcttaa ttatcttaga     3540

gatgggaatg gaaccaccag tggtgtaggt actggaagca gtgttgaaaa atacgtaatc     3600

gatgaaaatg attatatgtc attcataaac aaccccagcc tcaccgtcac agtgccaatt     3660

gctgttggag agtctgactt tgaaaactta aatactgaag agttcagcag tgagtcagaa     3720

ctagaagaaa gcaaagagaa attaaatgca accagctcat ctgaaggaag cacagttgat     3780

gttgttctac cccgagaagg tgaacaagct gaaactgaac ccgaagaaga ccttaaaccg     3840

gaagcttgtt ttactgaagg atgtattaaa aagtttccat tctgtcaagt aagtacagaa     3900

gaaggcaaag ggaagatctg gtggaatctt cgaaaaacct gctacagtat tgttgagcac     3960

aactggtttg agactttcat tgtgttcatg atccttctca gtagtggtgc attggccttt     4020

gaagatatat acattgaaca gcgaaagact atcaaaacca tgctagaata tgctgacaaa     4080

gtctttacct atatattcat tctggaaatg cttctcaaat gggttgctta tggatttcaa     4140

acatatttca ctaatgcctg gtgctggcta gatttcttga tcgttgatgt ttctttggtt     4200

agcctggtag ccaatgctct tggctactca gaactcggtg ccatcaaatc attacggaca     4260

ttaagagctt taagacctct aagagcctta tcccggtttg aaggcatgag ggtggttgtg     4320

aatgctcttg ttggagcaat tccctctatc atgaatgtgc tgttggtctg tctcatcttc     4380

tggttgatct ttagcatcat gggtgtgaat ttgtttgctg gcaagttcta ccactgtgtt     4440

aacatgacaa cgggtaacat gtttgacatt agtgatgtta acaatttgag tgactgtcag     4500

gctcttggca agcaagctcg gtggaaaaac gtgaaagtaa actttgataa tgttggcgct     4560

ggctatcttg cactgcttca agtggccaca tttaaaggct ggatggatat tatgtatgca     4620

gctgttgatt cacgagatgt taaacttcag cctgtatatg aagaaaatct gtacatgtat     4680

ttatactttg tcatctttat catctttggg tcattcttca ctctgaatct attcattggt     4740

gtcatcatag ataacttcaa ccagcagaaa aagaagtttg gaggtcaaga catctttatg     4800

acagaggaac agaaaaaata ttacaatgca atgaagaaac ttggatccaa gaaacctcag     4860

aaacccatac ctcgcccagc aaacaaattc caaggaatgg tctttgattt tgtaaccaga     4920

caagtctttg atatcagcat catgatcctc atctgcctca acatggtcac catgatggtg     4980

gaaacggatg accagggcaa atacatgacc ctagttttgt cccggatcaa cctagtgttc     5040

attgttctgt tcactggaga atttgtgctg aagctcgtct ccctcagaca ctactacttc     5100

actataggct ggaacatctt tgactttgtg gtggtgattc tctccattgt aggtatgttt     5160

ctggctgaga tgatagaaaa gtattttgtg tcccctacct tgttccgagt gatccgtctt     5220

gccaggattg gccgaatcct acgtctgatc aaaggagcaa aggggatccg cacgctgctc     5280

tttgctttga tgatgtccct tcctgcgttg tttaacatcg gcctcctgct cttcctggtc     5340

atgtttatct atgccatctt tgggatgtcc aactttgcct atgttaaaaa ggaagctgga     5400

attgatgaca tgttcaactt tgagaccttt ggcaacagca tgatctgctt gttccaaatt     5460

acaacctctg ctggctggga tggattgcta gcacctattc ttaatagtgc accacccgac     5520

tgtgaccctg acacaattca ccctggcagc tcagttaagg gagactgtgg gaacccatct     5580

gttgggattt tcttttttgt cagttacatc atcatatcct tcctggttgt ggtgaacatg     5640

tacatcgcgg tcatcctgga gaacttcagt gttgctactg aagaaagtgc agagcccctg     5700

agtgaggatg actttgagat gttctatgag gtttgggaaa agtttgatcc cgatgcgacc     5760

cagtttatag agttctctaa actctctgat tttgcagctg ccctggatcc tcctcttctc     5820

atagcaaaac ccaacaaagt ccagcttatt gccatggatc tgcccatggt cagtggtgac     5880

cggatccact gtcttgatat tttatttgcc tttacaaagc gtgttttggg tgagagtgga     5940

gagatggatg cccttcgaat acagatggaa gacaggttta tggcatcaaa cccctccaaa     6000

gtctcttatg agcctattac aaccactttg aaacgtaaac aagaggaggt gtctgccgct     6060

atcattcagc gtaatttcag atgttatctt ttaaagcaaa ggttaaaaaa tatatcaagt     6120

aactataaca aagaggcaat taaagggagg attgacttac ctataaaaca agacatgatt     6180

attgacaaac taaatgggaa ctccactcca gaaaaaacag atgggagttc ctctaccacc     6240

tctcctcctt cctatgatag tgtaacaaaa ccagacaagg aaaagtttga gaaagacaaa     6300

ccagaaaaag aaagcaaagg aaaagaggtc agagaaaatc aaaagtaaaa agaaacaaag     6360

aattatcttt gtgatcaatt gtttacagcc tatgaaggta aagtatatgt gtcaactgga     6420

cttcaagagg aggtccatgc caaactgact gttttaacaa atactcatag tcagtgccta     6480

tacaagacag tgaagtgacc tctctgtcac tgcaactctg tgaagcaggg tatcaacatt     6540

gacaagaggt tgctgttttt attaccagct gacactgctg aggagaaacc caatggctac     6600

ctagactata gggatagttg tgcaaagtga acattgtaac tacaccaaac acctttagta     6660

cagtccttgc atccattcta tttttaactt ccatatctgc catattttta caaaatttgt     6720

tctagtgcat ttccatggtc cccaattcat agtttattca taatgctatg tcactatttt     6780

tgtaaatgag gtttacgttg aagaaacagt atacaagaac cctgtctctc aaatgatcag     6840

acaaaggtgt tttgccagag agataaaatt tttgctcaaa accagaaaaa gaattgtaat     6900

ggctacagtt tcagttactt ccattttcta gatggcttta attttgaaag tattttagtc     6960

tgttatgttt gtttctatct gaacagttat gtgcctgtaa agtctcctct aatatttaaa     7020

ggattatttt tatgcaaagt attctgtttc agcaagtgca aattttattc taagtttcag     7080

agctctatat ttaatttagg tcaaatgctt tccaaaaagt aatctaataa atccattcta     7140

gaaaaatata tctaaagtat tgctttagaa tagttgttcc actttctgct gcagtattgc     7200

tttgccatct tctgctctca gcaaagctga tagtctatgt caattaaata ccctatgtta     7260

tgtaaatagt tattttatcc tgtggtgcat gtttgggcaa atatatatat agcctgataa     7320

acaacttcta ttaaatcaaa tatgtaccac agtgtatgtg tcttttgcaa gcttccaaca     7380

gggatgtatc ctgtatcatt cattaaacat agtttaaagg ctatcactaa tgcatgttaa     7440

tattgcctat gctgctctat tttactcaat ccattcttca caagtcttgg ttaaagaatg     7500

tcacatattg gtgatagaat gaattcaacc tgctctgtcc attatgtcaa gcagaataat     7560

ttgaagctat ttacaaacac ctttactttt gcacttttaa ttcaacatga gtatcatatg     7620

gtatctctct agatttcaag gaaacacact ggatactgcc tactgacaaa acctattctt     7680

catattttgc taaaaatatg tctaaaactt gtttaaatat aaataatgta aaaatataat     7740

caactttatt tgtcagcatt ttgtacataa gaaaattatt ttcaggttga tgacatcaca     7800

atttatttta ctttatgctt ttgcttttga tttttaatca caattccaaa cttttgaatc     7860

cataagattt ttcaatggat aatttcctaa aataaaagtt agataatggg ttttatggat     7920

ttctttgtta taatatattt tctaccattc caataggaga tacattggtc aaacactcaa     7980

acctagatca ttttctacca actatggttg cctcaatata accttttatt catagatgtt     8040

tttttttatt caacttttgt agtatttacg tatgcagact agtcttattt ttttaattcc     8100

tgctgcacta aagctattac aaatataaca tggactttgt tctttttagc catgaacaaa     8160

gtggcaaagt tgtgcaatta cctaacatga tataaatttt tgttttttgc acaaaccaaa     8220

agtttaatgt taattctttt tacaaaacta tttactgtag tgtattgaag aactgcatgc     8280

agggaattgc tattgctaaa aagaatggtg agctacgtca ttattgagcc aaaagaataa     8340

atttcatttt ttattgcatt tcacttattg gcctctgggg ttttttgttt ttgttttttg     8400

ctgttggcag tttaaaatat atataattaa taaaacctgt gcttgatctg acatttgtat     8460

acataaaagt ttacatgaat tttacaacaa actagtgcat gattcaccaa gcagtactac     8520

agaacaaagg caaattaaaa gcagctttgt gaacttttat gtgtgcaaag gatcaagttc     8580

acatgttcca actttcaggt ttgataataa tagtagtaac cacctacaat agctttcaat     8640

ttcaattaac tcccttggct ataagcatct aaactcatct tctttcaata taattgatgc     8700

tatctcctaa ttacttggtg gctaataaat gttacattct ttgttactta aatgcattat     8760

ataaactcct atgtatacat aaggtattaa tgatatagtt attgagaatt tatattaact     8820

tttttttcaa gaacccttgg atttatgtga ggtcaaaacc aaactcttat tctcagtgga     8880

aaactccagt tgtaatgcat atttttaaag acaatttgga tctaaatatg tatttcataa     8940

ttctcccata ataaattata taaggtggct aattggaaaa aaaaaaaaaa aaaa           8994


<210>  680
<211>  5635
<212>  DNA
<213>  homo sapiens

<400>  680
aaagccttcc caagccccca aggcatgctg ggagatgcag tccctttttc taaagactgg       60

ggcggccgtg aggtcatcgg tggtcgccgg gagccgccag cacgtggcgg cgaggaaggg      120

gcggtgtgct cctgttgtct gcacctgaga gggggcagga gctctcggcg cttgcgcctc      180

ccgccgcggt gccctcccga catgccggag gaggcgggct tcccgccggc caagagattc      240

cggccaggct ctggacctcc gagccgcgct gggtccttcc ctcccgggag gcaagtggtg      300

atgctgctga ctgcgggcag cggcggcaga ggaggaggag gaggccggag gcagcagccg      360

cccctggccc agccctcggc cagtccctac cctgaagctg tggagctgca gcgccggagt      420

ctgcccatct tccaagcgcg ggggcaactg ttggcccagc tccgaaacct ggacaacgcg      480

gtcctcatcg gggaaactgg ctctgggaag acaactcaga tccctcagta cctgtatgaa      540

ggagggatca gccgccaggg catcattgct gtgacccagc ctcgtcgagt agctgccatc      600

tctcttgcta ctagagtctc agatgagaag agaactgaac ttgggaagct ggttggctat      660

acagtgcgct ttgatgatgt cacctcagaa gacaccagga tcaagtttct gacagatggc      720

atgcttctgc gtgaagcaat ttcagactct ttgcttcgga aatacagctg tgtcattttg      780

gatgaagctc acgaacggac tatccacaca gatgtgctct ttggagtggt gaaagctgca      840

cagaagagga gaaaggaact cgggaaactt cctctgaaag tgattgtgat gtcagctacg      900

atggatgtgg acctgttctc tcagtatttc aatggcgccc ccgtcctcta cctagagggt      960

cggcagcatc cgatccaggt gttttacacc aaacagcctc agaatgatta cctgcacgcc     1020

gcgcttgtct ccgtcttcca gatccaccag gaagcccctt cttcacagga catcctggtg     1080

ttcctcactg ggcaggagga gatcgaagcc atgagcaaga cgtgccgaga cattgcaaag     1140

cacctcccag acggctgccc tgcgatgctg gtccttcctc tgtacgcctc cctgccctat     1200

gcacagcagc tccgagtctt ccaaggggcc ccaaagggct atcgcaaagt gatcatttca     1260

accaacatcg ctgaaacctc cataaccatt acaggaataa aatatgtagt tgacacgggc     1320

atggttaaag caaagaagta taaccctgac agtggtcttg aggtgttagc agtgcagcgg     1380

gtatcgaaga cgcaggcttg gcagcgcaca gggagggctg gcagagagga cagtggcatc     1440

tgctaccggc tctacacgga ggacgagttt gagaagtttg ataagatgac cgtgccagag     1500

atccagaggt gtaacctggc cagtgtgatg cttcagcttc tagcaatgaa agtcccaaat     1560

gtgctcacct ttgacttcat gtcgaagcca tctccagatc acattcaggc ggccattgcc     1620

caactggacc tgttaggtgc tcttgaacat aaggatgacc agcttaccct gactccaatg     1680

ggaagaaaga tggcagcatt tcctttagaa cccaaatttg ccaaaaccat cctcatgtcc     1740

cccaaattcc actgtacaga ggagatcctg accattgtct ccctgctgtc tgtggacagc     1800

gtcctccaca accctccttc ccggcgagag gaagtgcaag gggtccgcaa gaagttcata     1860

tccagcgagg gggatcacat gaccctgctc aatatctatc ggaccttcaa aaacctaggc     1920

ggaaataagg attggtgcaa agagaatttt gtcaacagca agaatatgac gctggtagca     1980

gaagtcagag cacagctgag ggacatctgc ttaaagatgt caatgccaat cgcatcatcc     2040

cgaggagacg tggagagtgt ccgccgctgc ctggctcaca gcctcttcat gagcaccgcc     2100

gagcttcagc cagatggcac ctatgccacc acggacaccc accagccagt ggccatccac     2160

ccgtcgtctg tcctcttcca ctgcaagccg gcctgcgtcg tgtacactga gctgctctac     2220

accaacaagt gctacatgcg ggacctctgc gtcatagatg cacagtggct gtacgaggct     2280

gcccctgagt actttaggag gaagctgaga accgccagaa actgagccgc cccaggatgc     2340

cgccagaatc actggtccct gggagcttgg actacagttg tccttacagc aggcttccag     2400

gttggcgctt agagaagcct tggaatcagc tgaaggtgcc tgacttccag gagcgtgaaa     2460

gcatctttgc tcaactcctg ggactgaacc atatagacat ggacatatca tttgtacctg     2520

gaaacctcaa aattatgctt ttggttctta ctgggtgact ttgacttaat ttaacacctg     2580

agcctcagtt ttctcatctg ccaaatggga gtaataataa taatccttat aaaattgggt     2640

tcataaagtt tagagaaaag gaatggaaag tacccagaac tatgcctgga gcacgcacga     2700

cacacgtaca gtgagttggg agccgttagg ctgaatgtta ctgcttgcca tatgatgtga     2760

agtacagcaa tatcccaagt tcttgtgact gagggagatt ttctggaagg gccacaggag     2820

gttgcggagc ttggatgttg cccttagttc ttgtttaatg tctctctgaa tgcagtttta     2880

aaatagaaaa caaaactgac ttctgtagaa gtttccagag ggaggtgctg ttatctcgta     2940

cctcctggga tggcgatccc tactgaacgc ttgtgtctca gggtggacca ctctgtgtct     3000

gtctccaagc agagaccagt aaaggagcct cctggtcctc agtgcgtgac cctgtcagtg     3060

ctttcaggag acatgtaagc ttcctgggtg aaggttgatt tgtaccttct gaatcctgtc     3120

acgtgtagac atgggaaact gacctatcag tgttttgtgt gtgtaggtga ctcccacata     3180

cacagttgcc atttttctct ctaactgggc accagtgaac atgcgggcat gaggagtgac     3240

tgtgtaccat ttcagctgtt tcttttcggg cagtcccctg gtcagagggg gtgggggtgg     3300

gggaggggag aggggtacct agaacccaga gaacattggc ttatgccaga taccacacca     3360

catctgggct tacattcttg tatctttttt ggtgtgtggg cggggggggt ggggggcagt     3420

tcagtgaagt ctagaagacc tgctggacaa attctaaaag agctagagct gtaacactta     3480

ttcttgcatc ttattaattt tctatgatat tttttccttc ttcgtaggga cttgggacaa     3540

tctggctttg ctgctttcta actgctaggc acctctctct aaccctcatt gtcagaggga     3600

attggaggat atccacagtc tgttcctgtt ctgatattct gagcagagaa aaggcactaa     3660

cggttcctct tagctattta attatcagaa gcaagtaatc tttccccaga taatattttg     3720

ccctagaaga agccgtgatt tagctctttt attgtgctta cttggtccaa atacatctgt     3780

ggggtgtttt gtcatttctt aatgaatgaa tcatagttat aaccaggggc caagctgccc     3840

aagaggctct tcagagatca tggatgctct ctttctggaa gctgtggcct gatggagcag     3900

ccccattcca gggtcccatc tgtccggagt tgtgtatgtc aagtccggct cagtctttat     3960

ttccaacact agccgtggtc ctgtgcagtc aagctctcag ctagtgttta gggctgtctg     4020

tcagaaatgg ttatacgtgg gcaaaagaag atctgacagc tcctatatac cttatcttac     4080

tgaattctta aactttgaac cagttcttcc acttactgac ttgttaccac tgctgacttt     4140

ctgaaaagtt ttccagtttt tgttttttgt tttttgtttt ccagtagggg attagaatgt     4200

ttagtcctac ttagtaagaa aaatattgta tttttaatca ttcatagtgc tggtaaaaaa     4260

aaaaaaaaaa aaaaaaaaat tggggggtgg ccgggcgcag tggctcacac ctgtaatccc     4320

agcactttgg gaggccaagg cgggcggatc acctcatgcc tgtaatccca gcattgggat     4380

gggaggctga ggtgggtgga ttgcttgaga agttcaagac cagcctggcc aacatggcaa     4440

aaccccgtct ctactaaaaa tagaaaactt agctgggcat ggtggcacac gcctgtaatc     4500

ccagctaccg gggaggctga ggcacaagaa ttgcttgaac ttgggaggca gagtttgtag     4560

tgagccaaga tcacgccact gcattccagc ctggccgaca gtgtgagacg gtctcagaaa     4620

aaaaaagaaa gaaagaaaga aaaagaaaaa acttggggta atttatgtcc agcttaagta     4680

cctgaacagt ttccggaaat gtatattttt tttctgagag gcaaaggatg taaacagctt     4740

ctaagtagct ttaatgtttc tgtacagaaa taagtttatc cctgtaacat tgtggtagag     4800

ttttaataca gtatttagtt ttttattggg cttttttaaa aagttaactt ttaacatagc     4860

tgctcaggga ttaaatcaga ttggaaaacc cattctgact ccacatactg ctacaaagaa     4920

atacatcgtt gtttatattg agctgcagga gatagtacac tttaaactta agaaagttaa     4980

atgtttcaca ataacattgc aatataatct tcagctactc tctttccatt ggtaaaatct     5040

ctgatggtgt gataactctt tgccaaccta cgaaacccat atctggaaga atcaccagct     5100

cccgtgagca gcttcatgta aatagatgca ctccaagcag attgcatgcc tcaggtgttt     5160

gtcttctagt aatcatggag tgtgcaacac ccagagtaac actacaaggg gcaggactgc     5220

aaacagcagg tcctggctaa aaacccttaa tgctgcattg ctgccagttg taaagagatg     5280

cctgaatgga ggcaagttct gccctgtggg tgaaactgat gatgtactgt actgtcatat     5340

ataaatccac taaatccagc taccaggaac tgcctggaac tgtggccatg catttttttt     5400

tttctttaaa gaccagtgtg atagtaggcc atgcatctga gatacgatat tccttggtaa     5460

ctagagggag aaaaaaaaat caagtaggtt caggcttatg ttgtattttg agagtctggt     5520

tttatttgaa cagaaataac tctacagaaa gctcttgtaa ataatgctca aatttgcacc     5580

cgacgatcaa atccattaaa aatgaatctt gtatatgaaa aaaaaaaaaa aaaaa          5635


<210>  681
<211>  2053
<212>  DNA
<213>  homo sapiens

<400>  681
cttccgtcgg ccattttagg tggtccgcgg cggcgccatt aaagcgagga ggaggcgaga       60

gcggccgccg ctggtgctta ttctttttta gtgcagcggg agagagcggg agtgtgcgcc      120

gcgcgagagt gggaggcgaa gggggcaggc cagggagagg cgcaggagcc tttgcagcca      180

cgcgcgcgcc ttccctgtct tgtgtgcttc gcgaggtaga gcgggcgcgc ggcagcggcg      240

gggattactt tgctgctagt ttcggttcgc ggcagcggcg ggtgtagtct cggcggcagc      300

ggcggagaca ctagcactat gtcggaggag cagttcggcg gggacggggc ggcggcagcg      360

gcaacggcgg cggtaggcgg ctcggcgggc gagcaggagg gagccatggt ggcggcgaca      420

cagggggcag cggcggcggc gggaagcgga gccgggaccg ggggcggaac cgcgtctgga      480

ggcaccgaag ggggcagcgc cgagtcggag ggggcgaaga ttgacgccag taagaacgag      540

gaggatgaag ggaaaatgtt tataggaggc cttagctggg acactacaaa gaaagatctg      600

aaggactact tttccaaatt tggtgaagtt gtagactgca ctctgaagtt agatcctatc      660

acagggcgat caaggggttt tggctttgtg ctatttaaag aatcggagag tgtagataag      720

gtcatggatc aaaaagaaca taaattgaat gggaaggtga ttgatcctaa aagggccaaa      780

gccatgaaaa caaaagagcc ggttaaaaaa atttttgttg gtggcctttc tccagataca      840

cctgaagaga aaataaggga gtactttggt ggttttggtg aggtggaatc catagagctc      900

cccatggaca acaagaccaa taagaggcgt gggttctgct ttattacctt taaggaagaa      960

gaaccagtga agaagataat ggaaaagaaa taccacaatg ttggtcttag taaatgtgaa     1020

ataaaagtag ccatgtcgaa ggaacaatat cagcaacagc aacagtgggg atctagagga     1080

ggatttgcag gaagagctcg tggaagaggt ggtgaccagc agagtggtta tgggaaggta     1140

tccaggcgag gtggtcatca aaatagctac aaaccatact aaattattcc atttgcaact     1200

tatccccaac aggtggtgaa gcagtatttt ccaatttgaa gattcatttg aaggtggctc     1260

ctgccacctg ctaatagcag ttcaaactaa attttttgta tcaagtccct gaatggaagt     1320

atgacgttgg gtccctctga agtttaattc tgagttctca ttaaaagaaa tttgctttca     1380

ttgttttatt tcttaattgc tatgcttcag aatcaatttg tgttttatgc cctttccccc     1440

agtattgtag agcaagtctt gtgttaaaag cccagtgtga cagtgtcatg atgtagtagt     1500

gtcttactgg ttttttaata aatccttttg tataaaaatg tattggctct tttatcatca     1560

gaataggaaa aattgtcatg gattcaagtt attaaaagca taagtttgga agacaggctt     1620

gccgaaattg aggacatgat taaaattgca gtgaagtttg aaatgttttt agcaaaatct     1680

aatttttgcc ataatgtgtc ctccctgtcc aaattgggaa tgacttaatg tcaatttgtt     1740

tgttggttgt tttaataata cttccttatg tagccattaa gatttatatg aatattttcc     1800

caaatgccca gtttttgctt aatatgtatt gtgcttttta gaacaaatct ggataaatgt     1860

gcaaaagtac ccctttgcac agatagttaa tgttttatgc ttccattaaa taaaaaggac     1920

ttaaaatctg ttaattataa tagaaatgcg gctagttcag agagattttt agagctgtgg     1980

tggacttcat agatgaattc aagtgttgag ggaggattaa agaaatatat accgtgttta     2040

tgtgtgtgtg ctt                                                        2053


<210>  682
<211>  6615
<212>  DNA
<213>  homo sapiens

<400>  682
agctccagcc gcactgcccc gatggctccc tacccctgtg gctgccacat cctgctgctg       60

ctcttctgct gcctggcggc tgcccgggcc aacctgctga acctgaactg gctttggttc      120

aataatgagg acaccagcca tgcagctacc acgatccctg agccccaggg gcccctgcct      180

gtgcagccca cagcagatac caccacacac gtgacccccc ggaatggttc cacagagcca      240

gcgacagccc ctggcagccc tgagccaccc tcagagctgc tggaagatgg ccaggacacc      300

cccacttctg ccgagagccc ggacgcgcca gaggagaaca ttgccggtgt cggagccgag      360

atcctgaacg tggccaaagg catccggagc ttcgtccagc tgtggaatga cactgtcccc      420

actgagagct tggccagggc ggaaaccctg gtcctggaga ctcctgtggg cccccttgcc      480

ctcgctgggc cttccagcac cccccaggag aatgggacca ctctctggcc cagccgtggc      540

attcctagct ctccgggcgc ccacacaacc gaggctggca ccttgcctgc acccacccca      600

tcgcctccct ccctgggcag gccctgggca ccactcacgg ggccctcagt gccaccacca      660

tcttcaggta gagcttctct ctcctccttg ctgggcgggg cccctccctg gggaagcctg      720

caggacccag acagccaagg actctcgccc gccgcagccg ctcccagcca gcagctccaa      780

cgccctgacg tccgcctgcg cacgccactt ctgcaccccc tggtgatggg ctccctgggc      840

aagcacgcgg ccccctccgc cttctcctct gggctcccgg gcgcactgtc tcaggtcgca      900

gtcaccactt taaccaggga cagcggtgct tgggtctccc acgtggctaa ctctgtgggg      960

ccgggtcttg ctaataactc tgccctgctc ggggctgacc ccgaggcccc cgccggtcgc     1020

tgcctgcccc tgccaccctc cctgccagtc tgcggccacc tgggcatctc acgcttctgg     1080

ctgcccaacc acctccacca cgagagcggc gagcaggtgc gggccggggc acgggcgtgg     1140

gggggcctgc tgcagacgca ctgccacccc ttcctcgcct ggttcttctg cctgctgctg     1200

gtccccccat gcggcagcgt cccgccgccc gccccgccac cctgctgcca gttctgcgag     1260

gccctgcagg atgcgtgttg gagccgcctg ggcgggggcc ggctgcccgt cgcctgtgcc     1320

tcgctcccga cccaggagga tgggtactgt gtgctcattg ggccggctgc agagcgcatc     1380

agcgaggagg tggggctgct gcagctcctt ggggaccccc cgccccagca ggtcacccag     1440

acggatgacc ccgacgtcgg gctggcctac gtctttgggc cagatgccaa cagtggccaa     1500

gtggcccggt accacttccc cagcctcttc ttccgtgact tctcactgct gttccacatc     1560

cggccagcca cagagggccc aggggtgctg ttcgccatca cggactcggc gcaggccatg     1620

gtcttgctgg gcgtgaagct ctctggggtg caggacgggc accaggacat ctccctgctc     1680

tacacagaac caggtgcagg ccagacccac acagccgcca gcttccggct ccccgccttc     1740

gtcggccagt ggacacactt agccctcagt gtggcaggtg gctttgtggc cctctacgtg     1800

gactgtgagg agttccagag aatgccgctt gctcggtcct cacggggcct ggagctggag     1860

cctggcgccg ggctcttcgt ggctcaggcg gggggagcgg accctgacaa gttccagggg     1920

gtgatcgctg agctgaaggt gcgcagggac ccccaggtga gccccatgca ctgcctggac     1980

gaggaaggcg atgactcaga tggggcatcc ggagactctg gcagcgggct cggggacgcc     2040

cgggagcttc tcagggagga gacgggcgcg gccctaaaac ccaggctccc cgcgccaccc     2100

cccgtcacca cgccaccctt ggctggaggc agcagcacgg aagattccag aagtgaagaa     2160

gtcgaggagc agaccacggt ggcttcgtta ggagctcaga cacttcctgg ctcagattct     2220

gtctccacgt gggacgggag tgtccggacc cctgggggcc gcgtgaaaga gggcggcctg     2280

aaggggcaga aaggggagcc aggtgttccg ggcccacctg gccgggcagg ccccccagga     2340

tccccatgcc tacctggtcc cccgggtctc ccgtgcccag tgagtcccct gggtcctgca     2400

ggcccagcgt tgcaaactgt ccccggacca caaggacccc cagggcctcc ggggagggac     2460

ggcacccctg gaagggacgg cgagccgggc gaccccggtg aagacggaaa gccgggcgac     2520

accgggccac aaggcttccc cgggactcca ggggacgtag gtcccaaggg cgacaaggga     2580

gaccctgggg ttggagagag agggccccca ggaccccaag ggcctccagg gcccccagga     2640

ccctccttca gacacgacaa gctgaccttc attgacatgg agggatctgg cttcgggggc     2700

gatctggagg ccctgcgggg tcctcgaggc ttccctggac ctcccggacc ccccggtgtc     2760

ccaggcctgc ccggcgagcc aggccgcttt ggggtgaaca gctccgacgt cccaggaccc     2820

gccggccttc ctggtgtgcc tgggcgcgag ggtccccccg ggtttcctgg cctcccggga     2880

cccccaggcc ctccgggaag agaggggccc ccaggaagga ctgggcagaa aggcagcctg     2940

ggtgaagcag gcgccccagg acataagggg agcaagggag cccccggtcc tgctggtgct     3000

cgtggggaga gcggcctggc aggagccccc ggacctgctg gaccaccagg cccccctggg     3060

ccccctgggc ccccaggacc aggactcccc gctggatttg atgacatgga aggctccggg     3120

gggcccttct ggtcaacagc ccgaagcgct gatgggccac agggacctcc cggcctgccg     3180

ggacttaagg gggatcctgg cgtgcctggg ctgccggggg cgaagggaga agttggagca     3240

gatggagtcc ccgggttccc cggcctccct ggcagagagg gcattgctgg gccccagggg     3300

ccaaagggag acagaggcag ccggggagaa aagggagatc cagggaagga cggagtcggg     3360

cagccgggcc tccctggccc ccccggaccc ccgggacctg tggtctacgt gtcggagcag     3420

gacggatccg tcctgagcgt gccgggacct gagggccggc cgggtttcgc aggctttccc     3480

ggacctgcag gacccaaggg caacctgggc tctaagggcg aacgaggctc cccgggaccc     3540

aagggtgaga agggtgaacc gggcagcatc ttcagccccg acggcggtgc cctgggccct     3600

gcccagaaag gagccaaggg agagccgggc ttccgaggac ccccgggtcc atacggacgg     3660

ccggggtaca agggagagat tggctttcct ggacggccgg gtcgccccgg gatgaacgga     3720

ttgaaaggag agaaagggga gccgggagat gccagccttg gatttggcat gaggggaatg     3780

cccggccccc caggacctcc agggccccca ggccctccag ggactcctgt ttacgacagc     3840

aatgtgtttg ctgagtccag ccgccccggg cctccaggat tgccagggaa tcagggccct     3900

ccaggaccca agggcgccaa aggagaagtg ggcccccccg gaccaccagg gcagtttccg     3960

tttgactttc ttcagttgga ggctgaaatg aagggggaga agggagaccg aggtgatgca     4020

ggacagaaag gcgaaagggg ggagcccggg ggcggcggtt tcttcggctc cagcctgccc     4080

ggcccccccg gccccccagg cccacgtggc taccctggga ttccaggtcc caagggagag     4140

agcatccggg gccagcccgg cccacctgga cctcagggac cccccggcat cggctacgag     4200

gggcgccagg gccctcccgg ccccccaggc cccccagggc ccccttcatt tcctggccct     4260

cacaggcaga ctatcagcgt tcccggccct ccgggccccc ctgggccccc tgggccccct     4320

ggaaccatgg gcgcctcctc aggggtgagg ctctgggcta cacgccaggc catgctgggc     4380

caggtgcacg aggttcccga gggctggctc atcttcgtgg ccgagcagga ggagctctac     4440

gtccgcgtgc agaacgggtt ccggaaggtc cagctggagg cccggacacc actcccacga     4500

gggacggaca atgaagtggc cgccttgcag ccccccgtgg tgcagctgca cgacagcaac     4560

ccctacccgc ggcgggagca cccccacccc accgcgcggc cctggcgggc agatgacatc     4620

ctggccagcc cccctcgcct gcccgagccc cagccctacc ccggagcccc gcaccacagc     4680

tcctacgtgc acctgcggcc ggcgcgaccc acaagcccac ccgcccacag ccaccgcgac     4740

ttccagccgg tgctccacct ggttgcgctc aacagccccc tgtcaggcgg catgcggggc     4800

atccgcgggg ccgacttcca gtgcttccag caggcgcggg ccgtggggct ggcgggcacc     4860

ttccgcgcct tcctgtcctc gcgcctgcag gacctgtaca gcatcgtgcg ccgtgccgac     4920

cgcgcagccg tgcccatcgt caacctcaag gacgagctgc tgtttcccag ctgggaggct     4980

ctgttctcag gctctgaggg tccgctgaag cccggggcac gcatcttctc ctttgacggc     5040

aaggacgtcc tgaggcaccc cacctggccc cagaagagcg tgtggcatgg ctcggacccc     5100

aacgggcgca ggctgaccga gagctactgt gagacgtggc ggacggaggc tccctcggcc     5160

acgggccagg cctcctcgct gctggggggc aggctcctgg ggcagagtgc cgcgagctgc     5220

catcacgcct acatcgtgct ctgcattgag aacagcttca tgactgcctc caagtagcca     5280

ccgcctggat gcggatggcc ggagaggacc ggcggctcgg aggaagcccc caccgtgggc     5340

agggagcggc cggccagccc ctggccccag gacctggctg ccatactttc ctgtatagtt     5400

cacgtttcat gtaatcctca agaaataaaa ggaagccaaa gagtgtattt ttttaaaagt     5460

ttaaaacaga agcctgatgc tgacattcac ctgccccaac tctcccctga cctgtgagcc     5520

cagctgggtc aggcagggtg cagtatcatg ccctgtgcaa cctcttggcc tgatcagacc     5580

acggctcgat ttctccagga tttcctgctt tgggaagccg tgctcgcccc agcaggtgct     5640

gacttcatct cccacctagc agcaccgttc tgtgcacaaa acccagacct gttagcagac     5700

aggccccgtg aggcaatggg agctgaggcc acactcagca caaggccatc tgggctcctc     5760

cagggtgtgt gctcgccctg cggtagatgg gagggaggct caggtccctg gggctagggg     5820

gagccccttc tgctcagctc tgggccattc tccacagcaa ccccaggctg aagcaggttc     5880

ccaagctcag aggcgcactg tgacccccag ctccggcctg tcctccaaca ccaagcacag     5940

cagcctgggg ctggcctccc aaatgagcca tgagatgata catccaaagc agacagctcc     6000

accctggccg agtccaagct gggagattca agggacccat gagttggggt ctggcagcct     6060

cccatccagg gcccccatct catgcccctg gctgggacgt ggctcagcca gcacttgtcc     6120

agctgagcgc caggatggaa cacggccaca tcaaagaggc tgaggctggc acaggacatg     6180

cggtagccag cacacagggc agtgagggag ggctgtcatc tgtgcactgc ccatggacag     6240

gctggctcca gatgcagggc agtcattggc tgtctcctag gaaacccata tccttaccct     6300

ccttgggact gaaggggaac cccggggtgc ccacaggccg ccctgcgggt gaacaaagca     6360

gccacgaggt gcaacaaggt cctctgtcag tcacagccac ccctgagatc cggcaacatc     6420

aacccgagtc attcgttctg tggagggaca agtggactca gggcagcgcc aggctgacca     6480

cagcacagcc aacacgcacc tgcctcagga ctgcgacgaa accggtgggg ctggttctgt     6540

aattgtgtgt gatgtgaagc caattcagac aggcaaataa aagtgacctt ttacactgaa     6600

aaaaaaaaaa aaaaa                                                      6615


<210>  683
<211>  12042
<212>  DNA
<213>  homo sapiens

<400>  683
gcgcgcgcgc aggctcttca gctggagcgg acacacggtg tgcgaaccga acagaataac       60

ccgcccccag cgggatgtga aggactccgg gtgaggccgg ccacgccccg cacggatggg      120

aaggccattg tgactatgtg gtgattacag ttgtcttact actgagtttc ctactgaaat      180

catggaggag aaacagcaga ttatattggc taatcaagat ggtggaacag tggcaggagc      240

agcacctacc ttctttgtca tcttaaagca gccaggaaat ggcaaaactg atcaaggaat      300

tttggttact aatcaggatg cctgtgcttt ggctagtagt gtgtcatcac cagtaaaatc      360

taaagggaag atttgccttc cagctgattg tactgtgggt ggaatcactg ttaccctcga      420

taacaatagt atgtggaatg agttctatca tcgaagcaca gagatgattc tgaccaagca      480

aggaagacgc atgtttcctt actgtcgtta ttggataaca ggtttagatt caaatttgaa      540

gtatattctt gtcatggata tatctcctgt ggataaccat cgttataagt ggaatggtcg      600

ttggtgggaa cctagtggga aggctgaacc tcatgttttg gggagggttt tcattcatcc      660

agaatctcct tccacaggtc attattggat gcatcaacca gtatctttct ataaactcaa      720

acttaccaac aatacactgg accaagaagg gcatatcatc ttgcactcta tgcatcgtta      780

cctgccgagg cttcatttgg tgcctgcaga aaaggctgtg gaggtgatac aattaaatgg      840

ccctggtgtc cacactttta ccttcccaca gactgaattc tttgcagtaa cagcttatca      900

gaacattcag attactcagc tgaaaataga ttacaatcca tttgccaaag gctttcggga      960

tgatgggctg aataataagc cccagagaga tggaaaacaa aagaacagct ctgaccaaga     1020

agggaataat atttccagtt cttctggtca tcgggtccgt cttacagaag gtcaggggtc     1080

agagatacaa ccaggtgatt tggatccttt gtcaaggggt catgaaacat caggcaaggg     1140

tttggagaag acttccctta atataaaacg agactttctt ggtttcatgg atactgattc     1200

agcacttagt gaagttcctc aattgaagca agagatttct gaatgtctta ttgccagcag     1260

ttttgaagat gactcccgtg tagcctcacc gttagaccag aacggaagct tcaatgttgt     1320

tattaaagag gaacctctag atgattatga ctacgaactt ggtgagtgcc cagaaggggt     1380

cactgtgaaa caggaagaga cagatgaaga gacggatgta tactcaaaca gtgatgatga     1440

tcctatacta gagaaacagc taaagaggca caataaagtt gacaacccag aagctgacca     1500

tctatcttct aaatggcttc caagcagccc atcaggtgtt gctaaagcta aaatgttcaa     1560

attagacact ggaaagatgc cagtagtcta tctggagccc tgtgctgtca ccagaagcac     1620

agttaagatt tctgaactcc ccgataacat gctttccaca tctcgaaagg ataaatcttc     1680

tatgttggca gaattggaat atttgcctac atacattgaa aattccaatg agactgcctt     1740

ctgcttaggc aaggaatcag aaaatggtct tagaaaacat tcaccagatc tcagagtggt     1800

acaaaaatat cccttactga aagagcctca gtggaaatat cctgatatat ctgacagcat     1860

tagcacagaa agaatactcg acgattcaaa ggattcagtt ggagactcac tttcaggaaa     1920

agaggacttg ggcagaaaga gaacaactat gcttaagatt gcaacagccg caaaggtagt     1980

gaatgctaat cagaatgcct ctccaaatgt ccctggaaaa agaggaaggc cacgaaaatt     2040

gaaactctgt aaggcaggac gaccacctaa gaacacagga aagtctttaa tttctacaaa     2100

gaatacacct gtaagccctg ggagtacctt tccagatgtg aagcctgatc tggaagatgt     2160

ggatggtgtt ctctttgttt cctttgaatc aaaggaagct ctagacattc atgcagttga     2220

tgggacaaca gaagaatctt ctagtctcca ggcatcaacc acaaatgact caggttacag     2280

agcaagaatt tcccagttgg aaaaggaatt gatagaagat ttgaagactt tgcggcacaa     2340

gcaggtgata catcctggtc ttcaagaagt gggcttaaaa ttgaattcag tggatccaac     2400

aatgagcatt gatcttaaat acttgggagt acagttacct ttggctccag ctactagctt     2460

tcctttttgg aaccttacag gaaccaaccc tgcctctcct gatgcgggat ttccctttgt     2520

ttctaggaca gggaaaacca atgatttcac taagatcaag ggatggaggg gaaaatttca     2580

tagtgcttct gcatctagga atgaaggtgg aaattcagaa agttcactga aaaatcgttc     2640

tgctttctgt agtgataagc tagatgaata cttggaaaat gaaggcaagc tgatggaaac     2700

aagcatgggt ttttcttcta atgctcccac atctcctgtg gtgtaccagc ttcccactaa     2760

gagtaccagt tatgtacgaa cacttgatag tgtactaaag aagcaatcta ctatttcccc     2820

ttctacctct tattctttga aacctcattc tgtaccccct gtctctcgaa aggcaaagtc     2880

tcaaaacaga caggcaactt tcagtggccg aactaaatca tcttataaat ccattttacc     2940

ataccctgtt tcaccaaagc agaaatactc tcatgtgatt ctaggagata aggttaccaa     3000

gaattcttca ggcatcatct cagaaaatca ggcgaataac tttgttgtgc caactttgga     3060

tgaaaatata tttccaaagc agattagttt gcggcaggca cagcagcagc agcaacagca     3120

acagggaagt cgccctccag gcttgtctaa atctcaggtg aagctaatgg acctggaaga     3180

ctgtgcactt tgggaaggaa aaccaaggac atacatcaca gaagagcgag cagatgtatc     3240

cttaacaact ctacttacag ctcaagcatc cctcaaaact aaacctatcc acacaatcat     3300

aaggaaacga gcccctccct gcaacaatga cttctgtcga ctgggttgtg tatgttccag     3360

tctagctttg gagaagcgcc aacctgctca ctgccgccga ccagactgca tgtttggttg     3420

tacttgtttg aaaagaaaag ttgtacttgt taaaggagga tccaaaacta agcattttca     3480

gaggaaggct gctcatcgag atccagtatt ttatgatact ctgggagagg aggcaaggga     3540

ggaggaagaa ggaatcaggg aggaggagga acaattgaaa gagaaaaaga agagaaagaa     3600

gctagaatac actatatgtg agacagagcc tgaacagcct gttcgacatt acccattatg     3660

ggtaaaagta gaaggtgaag tagatccaga accagtttat atccccacgc cttctgtcat     3720

tgagcctatg aaaccattgt tattgcctca gccagaagtt ttatctccta ctgtgaaggg     3780

caaactgctc actggaatta aatctccacg gtcatatact cccaaaccca atcctgtgat     3840

tcgggaagag gacaaagatc cagtctactt gtactttgaa agtatgatga cttgtgctcg     3900

agttcgagta tatgagcgaa aaaaagagga ccagagacaa ccatcttcct cctcctcccc     3960

atctccatca tttcagcagc aaacttcatg tcattctagc cctgagaacc ataataatgc     4020

aaaggaacct gattctgaac agcagccctt aaaacaactc acctgtgact tggaggatga     4080

ttctgataaa ttacaagaaa agagctggaa gtcttcctgc aatgaaggag aatcctcttc     4140

tacttcttat atgcatcaga ggtcacctgg tggtcccacc aaactgattg agatcatctc     4200

agactgcaac tgggaggaag atcggaacaa gattttgagc atcttatccc agcacatcaa     4260

tagcaacatg ccacaatcac ttaaggtggg cagcttcatc attgagttgg cttctcagcg     4320

aaagagccgg ggtgagaaga accctcctgt ttattcttct cgtgtgaaaa tctctatgcc     4380

atcatgtcaa gaccaagatg atatggctga gaaatctgga tcagagactc ctgatggtcc     4440

attgtcccct gggaaaatgg aggatatctc tcctgtgcag acagatgccc tggattcagt     4500

gagggagaga ttacatggag gcaaaggtct gcctttttat gcagggcttt ctcctgcagg     4560

gaagcttgtg gcctataaac gtaaacccag ttcaagtaca tctgggctta tccaggtagc     4620

atccaatgcc aaggtggctg catccaggaa accacgtacc ctgttgcctt caacatccaa     4680

ttccaaaatg gcatcctcct ctggcactgc aacaaatcgc cctgggaaga atctgaaggc     4740

gtttgtccca gcaaaacggc caattgcggc tcgaccctct cctggtggtg tgttcacaca     4800

gtttgtgatg agtaaagttg gagccttgca gcagaagata cctggagtta gcacacccca     4860

aaccctggca gggacacaga agttcagtat cagaccttct ccagtaatgg tcgtcacacc     4920

tgtggtttct tctgagccag ttcaggtgtg cagccctgtg actgctgctg tcactactac     4980

cacccctcaa gtgtttttag aaaatactac tgctgtgaca cctatgactg ctatttctga     5040

cgtggaaact aaagaaacta cttattcttc tggtgccacc actacagggg ttgttgaggt     5100

ctctgaaact aataccagca cctctgtaac atctacccag tctacagcca ctgtgaacct     5160

taccaaaacc actgggataa ctacccctgt ggcttcagtt gcttttccta agtctttggt     5220

agcatctcct tcaaccataa ctcttcctgt tgcttccact gcttccacct ccttagtcgt     5280

ggtgactgca gctgcatctt cctccatggt gaccacacca acttcatctc tgggctctgt     5340

tcctattata ctctcaggaa ttaatgggag tccaccagtg agccagagac cagaaaatgc     5400

tgctcaaatt ccagtggcta ctccacaggt ctctcctaac acagtgaaac gtgctggacc     5460

tcgattgttg ttgattccag tgcagcaggg ttctcctact cttagacctg tctcaaacac     5520

acaacttcag ggacatcgga tggtcttgca gcctgttagg agtccaagtg gaatgaactt     5580

attcaggcac cctaatgggc agattgtcca gcttctacct ttgcatcagc ttcgaggctc     5640

taatacccag cccaacttac agcctgtcat gtttcggaac ccagggtctg tgatgggaat     5700

ccggttacct gctccttcca aaccctctga gactccgcca tcttccactt cgtcctctgc     5760

tttctctgtc atgaatcctg taattcaagc tgttgggtct tcttcagcag tgaatgttat     5820

cactcaggca ccatcattgc tttcctctgg agctagtttt gtgtctcagg ctggtacatt     5880

gaccctgagg atttctcctc ctgaaccaca aagctttgca agtaaaacag gctctgaaac     5940

caaaataact tatagctcag gaggacagcc tgttggtaca gccagtctta ttcctctcca     6000

gtctggtagt tttgccttgt tacagctccc aggacaaaag cctgttccta gctccattct     6060

tcagcatgtt gcttcccttc agatgaagag agaatctcag aatccagacc agaaagatga     6120

aacaaactca ataaaaagag agcaagaaac gaagaaggtt ctacagtcag aaggagaggc     6180

tgtagaccct gaggctaatg taataaaaca aaactcagga gctgctacct cagaagaaac     6240

tctgaatgat tccttggaag ataggggtga tcatttggat gaagaatgcc ttccagaaga     6300

aggttgtgca actgtcaaac catctgagca ttcctgtatc actgggtcac atacagatca     6360

agattataaa gatgttaatg aagaatatgg ggctaggaat cgtaagagtt ccaaagaaaa     6420

agtggctgtt ctggaagtta ggaccatttc tgaaaaagcc agtaataaga cagtccaaaa     6480

tttaagtaaa gtacagcatc aaaaacttgg tgatgtgaag gtggaacagc agaaaggatt     6540

tgacaatcca gaagaaaact caagtgaatt tccagtcacc tttaaggaag aaagtaaatt     6600

tgaattgtca ggaagcaaag ttatggagca gcaatctaat ctacagccag aggccaaaga     6660

gaaggaatgt ggagactctc tggagaaaga cagggaaaga tggagaaaac atctgaaggg     6720

ccccttaacc aggaaatgtg ttggagcttc acaggaatgt aagaaagagg cagacgagca     6780

gttaattaaa gaaacaaaga catgtcagga aaattcagat gtgtttcagc aagaacaagg     6840

catctctgac ttacttggaa aaagtggaat tactgaagat gccagagttt tgaaaactga     6900

atgtgattct tggagtagga tttctaatcc ttcagccttc tccattgttc ctaggagagc     6960

tgcaaaaagc agcagaggga atggacattt tcagggtcac ttactgctac ctggagaaca     7020

gatacaacca aagcaagaga agaagggtgg gagaagcagt gctgacttca ctgttttgga     7080

tttggaagaa gatgatgaag atgataatga gaaaactgat gattctattg atgaaattgt     7140

ggatgttgtt tctgactacc agagtgagga ggttgatgat gtagaaaaga ataactgtgt     7200

agaatacatt gaggatgatg aggagcacgt ggacattgag actgtagaag agctctcaga     7260

ggaaattaat gttgctcacc tgaagaccac agcggcccac acacagtcat tcaaacagcc     7320

gtcctgtact cacatctctg cagatgaaaa agcagctgaa aggagtcgaa aggctccacc     7380

aattcctcta aaactgaagc ctgattactg gagtgacaaa ctacagaaag aagcagaagc     7440

gtttgcttat tatcgccgga cacacactgc caatgagcgg cggcggcgtg gtgaaatgag     7500

ggatctcttt gagaaattaa agatcacatt gggattactt cattcttcca aggtttccaa     7560

aagtctcatt cttactcgag ccttcagtga aattcaggga ctaacagatc aggcagacaa     7620

attgatagga cagaaaaatc tcctgactcg aaaacggaat attctgatac ggaaagtatc     7680

gtctctttca ggtaagacag aagaagtggt cctgaagaag ctagagtata tttatgcaaa     7740

acagcaagca ctagaggcac aaaaaagaaa aaagaagatg ggatcagatg agtttgacat     7800

atctcccaga attagcaaac agcaggaagg atcttctgca tcatctgtag atcttggaca     7860

gatgtttata aataacagga gggggaaacc tttgattctt tccagaaaaa aagaccaggc     7920

cacagaaaat acctcaccct tgaacactcc acacacctct gccaaccttg tgatgactcc     7980

gcaagggcaa ttgctcaccc taaaaggtcc cctattctca ggaccagtgg tagctgtttc     8040

tcctgatctc ttagaatctg atcttaagcc tcaagttgcc ggtagtgctg tggctctacc     8100

agaaaatgac gacttattta tgatgccacg aattgttaat gtgacatcat tggccacaga     8160

gggaggtttg gtagatatgg gtggcagcaa atatcctcat gaagttcctg atagcaagcc     8220

atctgaccat ctgaaagaca ccgtcaggaa tgaagataat tccttagagg ataagggtag     8280

aatctcttcc agaggaaaca gagatggcag agtgacgttg ggtccaacgc aggtttttct     8340

ggcaaacaaa gattctggtt atccacaaat agttgacgtt tccaatatgc agaaagcaca     8400

agagttctta cctaaaaaga tttctggtga tatgagaggg attcagtata aatggaaaga     8460

gagtgaatca agaggggaga gagtgaagtc aaaggattct tcatttcata aattaaagat     8520

gaaagatctc aaggactcaa gcatagagat ggaactgagg aaagtaacat cagctataga     8580

ggaagcagct cttgattcca gtgaactgct gactaacatg gaagatgagg atgatactga     8640

tgagacactg acttcactgc tcaatgaaat tgcctttctt aatcaacaac taaatgatga     8700

ctctgttggc ctggctgaac tacccagctc tatggataca gagttcccag gggatgctcg     8760

gcgggctttt attagtaagg ttcctcctgg aagcagagca actttccagg ttgagcactt     8820

gggaactggt ttgaaagagt tgcctgatgt tcaaggggag agtgactcta tcagtcccct     8880

cctcttgcac ttggaagacg atgacttttc tgagaatgaa aaacaacttg cagaaccagc     8940

ctctgagcca gatgtcctta agattgttat tgactctgaa ataaaggatt ccctcctttc     9000

caacaagaaa gctattgatg gagggaagaa tacttctggc ctccctgcag agcccgaaag     9060

tgtgtcctca ccccccaccc tacacatgaa gactggcttg gagaacagca acagcacaga     9120

cactttgtgg aggcctatgc caaagttggc ccctctaggt ttaaaagtag ctaatccttc     9180

cagtgatgca gatggtcaga gtctcaaggt gatgccttgt ttggcaccta tagctgccaa     9240

agttgggtca gttggacaca aaatgaactt aacagggaat gaccaggaag gccgggaaag     9300

caaggtgatg cctacattgg cacctgttgt ggctaaattg ggcaactcgg gggcctcacc     9360

aagttctgca gggaaatgaa cttacttgtc cttaagcaga agccaggctg tgaggggaaa     9420

tagatctcac ctcctttctc tgcaggcatc tgtttgtttg tgtcttagaa cttggatcct     9480

tgacttcaat gatgcagtgg ataatgatgg gagaaagggg gtagggtgct gaccctggta     9540

taagaagtac tctgaaattc tgatcatgtt aaaatgtgtt acctcacttg tggtgctggg     9600

tcccctcatc ctctctaaga agatgtgatc cattactgaa catgaggtgc ccctcttacc     9660

caaggaattt ataacatgac tctggctcca cagtggtttc tagttcttcc cccacaagcg     9720

aaagagctgt ttgcaacttt ggagttgctg tagactgaac tgtagcttgt agctgttgaa     9780

ttaagtccaa aatctaagga atgcgatgga cttgtgcaaa gggatccaga agagacactt     9840

tttagttgat gtttcaagaa tagggagaga gaggatgggt accatggaat accaaagtga     9900

aggactttgt gtcattcagt aaaattttct tttttcatat cctaagtagc tcccattccc     9960

tcaccttttc aatcagaatt aacaaattca agccttcagt aaagtaggga tgcttttaac    10020

ttttattatt aattattttg agatcttaaa aaaatagtag ttctccctta ttatttttgt    10080

gggcattgaa aagctcattt cacagtacca gagattttta ctgggagtat atattttgga    10140

ggtaggcata gagggagccc taccccttcc acaaattacg ttactcaaga gacagctaaa    10200

ataaaatgca ttatctcccc agaccagaga cagtggccaa aataaaaaat catggggctg    10260

gaaatttccc aaatcaaacc agcctcctgg tgcttgaagg tttcattcac tattacctgc    10320

acaggatgta aagaaaagtc acagtaggca ctctttacca gggaaataag gcagtatttg    10380

aatcacaaga tatatttttt atctgcaacc atggatccaa tgatctgtag agctttttca    10440

ctcattaact gtcaggatat gaaggactga cagtctgtaa agatatttat atttttgtat    10500

agttgttttc atagatttct caaaggctga agttttcaac ctagaagatg agatttgtat    10560

tgagtataga aatgatgttt cctatctagt ttgtaaataa tcatggtgca cttgaggggt    10620

ctcttggaaa ctcctagggg gtcaagaatc actattctga aactgtatag actgggattt    10680

agctgctgca ttttgccttt cttaaataat tatattttgg aatgtaaccc ctgttctgtc    10740

ttcattgaca ggatttgctt gtgttgttaa aacactaaca caagagcttc cagtgcctgg    10800

gccgtgccta ggtgatgcta tttcttctat atctcctgtc ttctttatcc caaatcccac    10860

tcagcatatc ttcagaccta ggttgtaaga ccaactttgg attggatcta gccagtgaat    10920

tattatttcc atggttggtt ccctttctgt taactctggt aatcaacaga ttgaaaacgg    10980

tggaagaact tctgaaaatt gcagtgggag caaattcttg ttggttttgt gctgcttgcc    11040

tttctagatc tgctcatcag cacttaacct tccctcctct aaaggttact aaagaagcct    11100

gaagtaggta aagagtgctc ctcagcttct tatccttcca ctctttaccc agcagatttc    11160

attcaatgcc ttagccaagg agtccagcac ctgtctcccc tgctaataat tgtccttaga    11220

gatgctagta ctttaatcca ggtatagcag tttcccgtta ttttcttgct tgtcgttccc    11280

ctacatttcc tcctgatttc ccaagactct ctttgtggct tttgagggtc agccaaggag    11340

caggcaagtg agtgaacaat cctcaggaaa agaaggacca ttttagctta acacttcctt    11400

tttttttttt ttttttttaa gaagaatata ggtaaacagg taatgattct tgattggaga    11460

taccatttga ctcttgatga gagttgtacg aagatggaaa tgagggatga ttccaggcgt    11520

tttaggggga aggctgcaga taccattcta acccccaaga tactgtgttc tcaagacctc    11580

ttagaactag gtgttgtcag ggataatttg aggagggctt agtcttcaga acaatcctgc    11640

agtcttgaca gaaatctaaa atctccaaaa actcctaccc tttaacctta ccctaggggg    11700

aactgatcta tgaatattac atgtgtgatt atgaaaggtg aagttgagtg agaggagttg    11760

aggaacgtgg aagacagtga gctctcaccc taacactata agaagcatga tctcaataga    11820

ccaataattc acctttttat acatctgtaa ataaatggaa tgtttttaag aatataatta    11880

tgtcagattt agcattttct tttatatatt aaatatatat atctttcctt ttctgctttc    11940

gaaaagtgac tattttttta gaaatctaag aacagaagtt tggtgattga aaggtagaat    12000

atataaacct gaaataaagc agttaaaaca attaaagcag aa                       12042


<210>  684
<211>  12507
<212>  DNA
<213>  homo sapiens

<400>  684
taccgggcgg aggtgagcgc ggcgccggct cctcctgcgg cggactttgg gtgcgacttg       60

acgagcggtg gttcgacaag tggccttgcg ggccggatcg tcccagtgga agagttgtaa      120

atttgcttct ggccttcccc tacggattat acctggcctt cccctacgga ttatactcaa      180

cttactgttt agaaaatgtg gcccacgaga cgcctggtta ctatcaaaag gagcggggtc      240

gacggtcccc actttcccct gagcctcagc acctgcttgt ttggaagggg tattgaatgt      300

gacatccgta tccagcttcc tgttgtgtca aaacaacatt gcaaaattga aatccatgag      360

caggaggcaa tattacataa tttcagttcc acaaatccaa cacaagtaaa tgggtctgtt      420

attgatgagc ctgtacggct aaaacatgga gatgtaataa ctattattga tcgttccttc      480

aggtatgaaa atgaaagtct tcagaatgga aggaagtcaa ctgaatttcc aagaaaaata      540

cgtgaacagg agccagcacg tcgtgtctca agatctagct tctcttctga ccctgatgag      600

aaagctcaag attccaaggc ctattcaaaa atcactgaag gaaaagtttc aggaaatcct      660

caggtacata tcaagaatgt caaagaagac agtaccgcag atgactcaaa agacagtgtt      720

gctcagggaa caactaatgt tcattcctca gaacatgctg gacgtaatgg cagaaatgca      780

gctgatccca tttctgggga ttttaaagaa atttccagcg ttaaattagt gagccgttat      840

ggagaattga agtctgttcc cactacacaa tgtcttgaca atagcaaaaa aaatgaatct      900

cccttttgga agctttatga gtcagtgaag aaagagttgg atgtaaaatc acaaaaagaa      960

aatgtcctac agtattgtag aaaatctgga ttacaaactg attacgcaac agagaaagaa     1020

agtgctgatg gtttacaggg ggagacccaa ctgttggtct cgcgtaagtc aagaccaaaa     1080

tctggtggga gcggccacgc tgtggcagag cctgcttcac ctgaacaaga gcttgaccag     1140

aacaagggga agggaagaga cgtggagtct gttcagactc ccagcaaggc tgtgggcgcc     1200

agctttcctc tctatgagcc ggctaaaatg aagacccctg tacaatattc acagcaacaa     1260

aattctccac aaaaacataa gaacaaagac ctgtatacta ctggtagaag agaatctgtg     1320

aatctgggta aaagtgaagg cttcaaggct ggtgataaaa ctcttactcc caggaagctt     1380

tcaactagaa atcgaacacc agctaaagtt gaagatgcag ctgactctgc cactaagcca     1440

gaaaatctct cttccaaaac cagaggaagt attcctacag atgtggaagt tctgcctacg     1500

gaaactgaaa ttcacaatga gccattttta actctgtggc tcactcaagt tgagaggaag     1560

atccaaaagg attccctcag caagcctgag aaattgggca ctacagctgg acagatgtgc     1620

tctgggttac ctggtcttag ttcagttgat atcaacaact ttggtgattc cattaatgag     1680

agtgagggaa tacctttgaa aagaaggcgt gtgtcctttg gtgggcacct aagacctgaa     1740

ctatttgatg aaaacttgcc tcctaatacg cctctcaaaa ggggagaagc cccaaccaaa     1800

agaaagtctc tggtaatgca cactccacct gtcctgaaga aaatcatcaa ggaacagcct     1860

caaccatcag gaaaacaaga gtcaggttca gaaatccatg tggaagtgaa ggcacaaagc     1920

ttggttataa gccctccagc tcctagtcct aggaaaactc cagttgccag tgatcaacgc     1980

cgtaggtcct gcaaaacagc ccctgcttcc agcagcaaat ctcagacaga ggttcctaag     2040

agaggaggga gaaagagtgg caacctgcct tcaaagagag tgtctatcag ccgaagtcaa     2100

catgatattt tacagatgat atgttccaaa agaagaagtg gtgcttcgga agcaaatctg     2160

attgttgcaa aatcatgggc agatgtagta aaacttggtg caaaacaaac acaaactaaa     2220

gtcataaaac atggtcctca aaggtcaatg aacaaaaggc aaagaagacc tgctactcca     2280

aagaagcctg tgggcgaagt tcacagtcaa tttagtacag gccacgcaaa ctctccttgt     2340

accataataa tagggaaagc tcatactgaa aaagtacatg tgcctgctcg accctacaga     2400

gtgctcaaca acttcatttc caaccaaaaa atggacttta aggaagatct ttcaggaata     2460

gctgaaatgt tcaagacccc agtgaaggag caaccgcagt tgacaagcac atgtcacatc     2520

gctatttcaa attcagagaa tttgcttgga aaacagtttc aaggaactga ttcaggagaa     2580

gaacctctgc tccccacctc agagagtttt ggaggaaatg tgttcttcag tgcacagaat     2640

gcagcaaaac agccatctga taaatgctct gcaagccctc ccttaagacg gcagtgtatt     2700

agagaaaatg gaaacgtagc aaaaacgccc aggaacacct acaaaatgac ttctctggag     2760

acaaaaactt cagatactga gacagagcct tcaaaaacag tatccactgc aaacaggtca     2820

ggaaggtcta cagagttcag gaatatacag aagctacctg tggaaagtaa gagtgaagaa     2880

acaaatacag aaattgttga gtgcatccta aaaagaggtc agaaggcaac actactacaa     2940

caaaggagag aaggagagat gaaggaaata gaaagacctt ttgagacata taaggaaaat     3000

attgaattaa aagaaaacga tgaaaagatg aaagcaatga agagatcaag aacttggggg     3060

cagaaatgtg caccaatgtc tgacctgaca gacctcaaga gcttgcctga tacagaactc     3120

atgaaagaca cggcacgtgg ccagaatctc ctccaaaccc aagatcatgc caaggcacca     3180

aagagtgaga aaggcaaaat cactaaaatg ccctgccagt cattacaacc agaaccaata     3240

aacaccccaa cacacacaaa acaacagttg aaggcatccc tggggaaagt aggtgtgaaa     3300

gaagagctcc tagcagtcgg caagttcaca cggacgtcag gggagaccac gcacacgcac     3360

agagagccag caggagatgg caagagcatc agaacgttta aggagtctcc aaagcagatc     3420

ctggacccag cagcccgtgt aactggaatg aagaagtggc caagaacgcc taaggaagag     3480

gcccagtcac tagaagacct ggctggcttc aaagagctct tccagacacc aggtccctct     3540

gaggaatcaa tgactgatga gaaaactacc aaaatagcct gcaaatctcc accaccagaa     3600

tcagtggaca ctccaacaag cacaaagcaa tggcctaaga gaagtctcag gaaagcagat     3660

gtagaggaag aattcttagc actcaggaaa ctaacaccat cagcagggaa agccatgctt     3720

acgcccaaac cagcaggagg tgatgagaaa gacattaaag catttatggg aactccagtg     3780

cagaaactgg acctggcagg aactttacct ggcagcaaaa gacagctaca gactcctaag     3840

gaaaaggccc aggctctaga agacctggct ggctttaaag agctcttcca gactcctggt     3900

cacaccgagg aattagtggc tgctggtaaa accactaaaa taccctgcga ctctccacag     3960

tcagacccag tggacacccc aacaagcaca aagcaacgac ccaagagaag tatcaggaaa     4020

gcagatgtag agggagaact cttagcgtgc aggaatctaa tgccatcagc aggcaaagcc     4080

atgcacacgc ctaaaccatc agtaggtgaa gagaaagaca tcatcatatt tgtgggaact     4140

ccagtgcaga aactggacct gacagagaac ttaaccggca gcaagagacg gccacaaact     4200

cctaaggaag aggcccaggc tctggaagac ctgactggct ttaaagagct cttccagacc     4260

cctggtcata ctgaagaagc agtggctgct ggcaaaacta ctaaaatgcc ctgcgaatct     4320

tctccaccag aatcagcaga caccccaaca agcacaagaa ggcagcccaa gacacctttg     4380

gagaaaaggg acgtacagaa ggagctctca gccctgaaga agctcacaca gacatcaggg     4440

gaaaccacac acacagataa agtaccagga ggtgaggata aaagcatcaa cgcgtttagg     4500

gaaactgcaa aacagaaact ggacccagca gcaagtgtaa ctggtagcaa gaggcaccca     4560

aaaactaagg aaaaggccca acccctagaa gacctggctg gcttgaaaga gctcttccag     4620

acaccagtat gcactgacaa gcccacgact cacgagaaaa ctaccaaaat agcctgcaga     4680

tcacaaccag acccagtgga cacaccaaca agctccaagc cacagtccaa gagaagtctc     4740

aggaaagtgg acgtagaaga agaattcttc gcactcagga aacgaacacc atcagcaggc     4800

aaagccatgc acacacccaa accagcagta agtggtgaga aaaacatcta cgcatttatg     4860

ggaactccag tgcagaaact ggacctgaca gagaacttaa ctggcagcaa gagacggcta     4920

caaactccta aggaaaaggc ccaggctcta gaagacctgg ctggctttaa agagctcttc     4980

cagacacgag gtcacactga ggaatcaatg actaacgata aaactgccaa agtagcctgc     5040

aaatcttcac aaccagaccc agacaaaaac ccagcaagct ccaagcgacg gctcaagaca     5100

tccctgggga aagtgggcgt gaaagaagag ctcctagcag ttggcaagct cacacagaca     5160

tcaggagaga ctacacacac acacacagag ccaacaggag atggtaagag catgaaagca     5220

tttatggagt ctccaaagca gatcttagac tcagcagcaa gtctaactgg cagcaagagg     5280

cagctgagaa ctcctaaggg aaagtctgaa gtccctgaag acctggccgg cttcatcgag     5340

ctcttccaga caccaagtca cactaaggaa tcaatgacta acgaaaaaac taccaaagta     5400

tcctacagag cttcacagcc agacctagtg gacaccccaa caagctccaa gccacagccc     5460

aagagaagtc tcaggaaagc agacactgaa gaagaatttt tagcatttag gaaacaaacg     5520

ccatcagcag gcaaagccat gcacacaccc aaaccagcag taggtgaaga gaaagacatc     5580

aacacgtttt tgggaactcc agtgcagaaa ctggaccagc caggaaattt acctggcagc     5640

aatagacggc tacaaactcg taaggaaaag gcccaggctc tagaagaact gactggcttc     5700

agagagcttt tccagacacc atgcactgat aaccccacga ctgatgagaa aactaccaaa     5760

aaaatactct gcaaatctcc gcaatcagac ccagcggaca ccccaacaaa cacaaagcaa     5820

cggcccaaga gaagcctcaa gaaagcagac gtagaggaag aatttttagc attcaggaaa     5880

ctaacaccat cagcaggcaa agccatgcac acgcctaaag cagcagtagg tgaagagaaa     5940

gacatcaaca catttgtggg gactccagtg gagaaactgg acctgctagg aaatttacct     6000

ggcagcaaga gacggccaca aactcctaaa gaaaaggcca aggctctaga agatctggct     6060

ggcttcaaag agctcttcca gacaccaggt cacactgagg aatcaatgac cgatgacaaa     6120

atcacagaag tatcctgcaa atctccacaa ccagacccag tcaaaacccc aacaagctcc     6180

aagcaacgac tcaagatatc cttggggaaa gtaggtgtga aagaagaggt cctaccagtc     6240

ggcaagctca cacagacgtc agggaagacc acacagacac acagagagac agcaggagat     6300

ggaaagagca tcaaagcgtt taaggaatct gcaaagcaga tgctggaccc agcaaactat     6360

ggaactggga tggagaggtg gccaagaaca cctaaggaag aggcccaatc actagaagac     6420

ctggccggct tcaaagagct cttccagaca ccagaccaca ctgaggaatc aacaactgat     6480

gacaaaacta ccaaaatagc ctgcaaatct ccaccaccag aatcaatgga cactccaaca     6540

agcacaagga ggcggcccaa aacacctttg gggaaaaggg atatagtgga agagctctca     6600

gccctgaagc agctcacaca gaccacacac acagacaaag taccaggaga tgaggataaa     6660

ggcatcaacg tgttcaggga aactgcaaaa cagaaactgg acccagcagc aagtgtaact     6720

ggtagcaaga ggcagccaag aactcctaag ggaaaagccc aacccctaga agacttggct     6780

ggcttgaaag agctcttcca gacaccaata tgcactgaca agcccacgac tcatgagaaa     6840

actaccaaaa tagcctgcag atctccacaa ccagacccag tgggtacccc aacaatcttc     6900

aagccacagt ccaagagaag tctcaggaaa gcagacgtag aggaagaatc cttagcactc     6960

aggaaacgaa caccatcagt agggaaagct atggacacac ccaaaccagc aggaggtgat     7020

gagaaagaca tgaaagcatt tatgggaact ccagtgcaga aattggacct gccaggaaat     7080

ttacctggca gcaaaagatg gccacaaact cctaaggaaa aggcccaggc tctagaagac     7140

ctggctggct tcaaagagct cttccagaca ccaggcactg acaagcccac gactgatgag     7200

aaaactacca aaatagcctg caaatctcca caaccagacc cagtggacac cccagcaagc     7260

acaaagcaac ggcccaagag aaacctcagg aaagcagacg tagaggaaga atttttagca     7320

ctcaggaaac gaacaccatc agcaggcaaa gccatggaca caccaaaacc agcagtaagt     7380

gatgagaaaa atatcaacac atttgtggaa actccagtgc agaaactgga cctgctagga     7440

aatttacctg gcagcaagag acagccacag actcctaagg aaaaggctga ggctctagag     7500

gacctggttg gcttcaaaga actcttccag acaccaggtc acactgagga atcaatgact     7560

gatgacaaaa tcacagaagt atcctgtaaa tctccacagc cagagtcatt caaaacctca     7620

agaagctcca agcaaaggct caagataccc ctggtgaaag tggacatgaa agaagagccc     7680

ctagcagtca gcaagctcac acggacatca ggggagacta cgcaaacaca cacagagcca     7740

acaggagata gtaagagcat caaagcgttt aaggagtctc caaagcagat cctggaccca     7800

gcagcaagtg taactggtag caggaggcag ctgagaactc gtaaggaaaa ggcccgtgct     7860

ctagaagacc tggttgactt caaagagctc ttctcagcac caggtcacac tgaagagtca     7920

atgactattg acaaaaacac aaaaattccc tgcaaatctc ccccaccaga actaacagac     7980

actgccacga gcacaaagag atgccccaag acacgtccca ggaaagaagt aaaagaggag     8040

ctctcagcag ttgagaggct cacgcaaaca tcagggcaaa gcacacacac acacaaagaa     8100

ccagcaagcg gtgatgaggg catcaaagta ttgaagcaac gtgcaaagaa gaaaccaaac     8160

ccagtagaag aggaacccag caggagaagg ccaagagcac ctaaggaaaa ggcccaaccc     8220

ctggaagacc tggccggctt cacagagctc tctgaaacat caggtcacac tcaggaatca     8280

ctgactgctg gcaaagccac taaaataccc tgcgaatctc ccccactaga agtggtagac     8340

accacagcaa gcacaaagag gcatctcagg acacgtgtgc agaaggtaca agtaaaagaa     8400

gagccttcag cagtcaagtt cacacaaaca tcaggggaaa ccacggatgc agacaaagaa     8460

ccagcaggtg aagataaagg catcaaagca ttgaaggaat ctgcaaaaca gacaccggct     8520

ccagcagcaa gtgtaactgg cagcaggaga cggccaagag cacccaggga aagtgcccaa     8580

gccatagaag acctagctgg cttcaaagac ccagcagcag gtcacactga agaatcaatg     8640

actgatgaca aaaccactaa aataccctgc aaatcatcac cagaactaga agacaccgca     8700

acaagctcaa agagacggcc caggacacgt gcccagaaag tagaagtgaa ggaggagctg     8760

ttagcagttg gcaagctcac acaaacctca ggggagacca cgcacaccga caaagagccg     8820

gtaggtgagg gcaaaggcac gaaagcattt aagcaacctg caaagcggaa gctggacgca     8880

gaagatgtaa ttggcagcag gagacagcca agagcaccta aggaaaaggc ccaacccctg     8940

gaagatctgg ccagcttcca agagctctct caaacaccag gccacactga ggaactggca     9000

aatggtgctg ctgatagctt tacaagcgct ccaaagcaaa cacctgacag tggaaaacct     9060

ctaaaaatat ccagaagagt tcttcgggcc cctaaagtag aacccgtggg agacgtggta     9120

agcaccagag accctgtaaa atcacaaagc aaaagcaaca cttccctgcc cccactgccc     9180

ttcaagaggg gaggtggcaa agatggaagc gtcacgggaa ccaagaggct gcgctgcatg     9240

ccagcaccag aggaaattgt ggaggagctg ccagccagca agaagcagag ggttgctccc     9300

agggcaagag gcaaatcatc cgaacccgtg gtcatcatga agagaagttt gaggacttct     9360

gcaaaaagaa ttgaacctgc ggaagagctg aacagcaacg acatgaaaac caacaaagag     9420

gaacacaaat tacaagactc ggtccctgaa aataagggaa tatccctgcg ctccagacgc     9480

caaaataaga ctgaggcaga acagcaaata actgaggtct ttgtattagc agaaagaata     9540

gaaataaaca gaaatgaaaa gaagcccatg aagacctccc cagagatgga cattcagaat     9600

ccagatgatg gagcccggaa acccatacct agagacaaag tcactgagaa caaaaggtgc     9660

ttgaggtctg ctagacagaa tgagagctcc cagcctaagg tggcagagga gagcggaggg     9720

cagaagagtg cgaaggttct catgcagaat cagaaaggga aaggagaagc aggaaattca     9780

gactccatgt gcctgagatc aagaaagaca aaaagccagc ctgcagcaag cactttggag     9840

agcaaatctg tgcagagagt aacgcggagt gtcaagaggt gtgcagaaaa tccaaagaag     9900

gctgaggaca atgtgtgtgt caagaaaata agaaccagaa gtcataggga cagtgaagat     9960

atttgacaga aaaatcgaac tgggaaaaat ataataaagt tagttttgtg ataagttcta    10020

gtgcagtttt tgtcataaat tacaagtgaa ttctgtaagt aaggctgtca gtctgcttaa    10080

gggaagaaaa ctttggattt gctgggtctg aatcggcttc ataaactcca ctgggagcac    10140

tgctgggctc ctggactgag aatagttgaa caccgggggc tttgtgaagg agtctgggcc    10200

aaggtttgcc ctcagctttg cagaatgaag ccttgaggtc tgtcaccacc cacagccacc    10260

ctacagcagc cttaactgtg acacttgcca cactgtgtcg tcgtttgttt gcctatgtcc    10320

tccagggcac ggtggcagga acaactatcc tcgtctgtcc caacactgag caggcactcg    10380

gtaaacacga atgaatggat gagcgcacgg atgaatggag cttacaagat ctgtctttcc    10440

aatggccggg ggcatttggt ccccaaatta aggctattgg acatctgcac aggacagtcc    10500

tatttttgat gtcctttcct ttctgaaaat aaagttttgt gctttggaga atgactcgtg    10560

agcacatctt tagggaccaa gagtgacttt ctgtaaggag tgactcgtgg cttgccttgg    10620

tctcttggga atacttttct aactagggtt gctctcacct gagacattct ccacccgcgg    10680

aatctcaggg tcccaggctg tgggccatca cgacctcaaa ctggctccta atctccagct    10740

ttcctgtcat tgaaagcttc ggaagtttac tggctctgct cccgcctgtt ttctttctga    10800

ctctatctgg cagcccgatg ccacccagta caggaagtga caccagtact ctgtaaagca    10860

tcatcatcct tggagagact gagcactcag caccttcagc cacgatttca ggatcgcttc    10920

cttgtgagcc gctgcctccg aaatctcctt tgaagcccag acatctttct ccagcttcag    10980

acttgtagat ataactcgtt catcttcatt tactttccac tttgccccct gtcctctctg    11040

tgttccccaa atcagagaat agcccgccat cccccaggtc acctgtctgg attcctcccc    11100

attcacccac cttgccaggt gcaggtgagg atggtgcacc agacagggta gctgtccccc    11160

aaaatgtgcc ctgtgcgggc agtgccctgt ctccacgttt gtttccccag tgtctggcgg    11220

ggagccaggt gacatcataa atacttgctg aatgaatgca gaaatcagcg gtactgactt    11280

gtactatatt ggctgccatg atagggttct cacagcgtca tccatgatcg taagggagaa    11340

tgacattctg cttgagggag ggaatagaaa ggggcaggga ggggacatct gagggcttca    11400

cagggctgca aagggtacag ggattgcacc agggcagaac aggggagggt gttcaaggaa    11460

gagtggctct tagcagaggc actttggaag gtgtgaggca taaatgcttc cttctacgta    11520

ggccaacctc aaaactttca gtaggaatgt tgctatgatc aagttgttct aacactttag    11580

acttagtagt aattatgaac ctcacataga aaaatttcat ccagccatat gcctgtggag    11640

tggaatattc tgtttagtag aaaaatcctt tagagttcag ctctaaccag aaatcttgct    11700

gaagtatgtc agcacctttt ctcaccctgg taagtacagt atttcaagag cacgctaagg    11760

gtggttttca ttttacaggg ctgttgatga tgggttaaaa atgttcattt aagggctacc    11820

cccgtgttta atagatgaac accacttcta cacaaccctc cttggtactg ggggagggag    11880

agatctgaca aatactgccc attcccctag gctgactgga tttgagaaca aatacccacc    11940

catttccacc atggtatggt aacttctctg agcttcagtt tccaagtgaa tttccatgta    12000

ataggacatt cccattaaat acaagctgtt tttacttttt cgcctcccag ggcctgtggg    12060

atctggtccc ccagcctctc ttgggctttc ttacactaac tctgtaccta ccatctcctg    12120

cctcccttag gcaggcacct ccaaccacca cacactccct gctgttttcc ctgcctggaa    12180

ctttccctcc tgccccacca agatcatttc atccagtcct gagctcagct taagggaggc    12240

ttcttgcctg tgggttccct cacccccatg cctgtcctcc aggctggggc aggttcttag    12300

tttgcctgga attgttctgt acctctttgt agcacgtagt gttgtggaaa ctaagccact    12360

aattgagttt ctggctcccc tcctggggtt gtaagttttg ttcattcatg agggccgact    12420

gcatttcctg gttactctat cccagtgacc agccacagga gatgtccaat aaagtatgtg    12480

atgaaatggt cttaaaaaaa aaaaaaa                                        12507


<210>  685
<211>  11427
<212>  DNA
<213>  homo sapiens

<400>  685
taccgggcgg aggtgagcgc ggcgccggct cctcctgcgg cggactttgg gtgcgacttg       60

acgagcggtg gttcgacaag tggccttgcg ggccggatcg tcccagtgga agagttgtaa      120

atttgcttct ggccttcccc tacggattat acctggcctt cccctacgga ttatactcaa      180

cttactgttt agaaaatgtg gcccacgaga cgcctggtta ctatcaaaag gagcggggtc      240

gacggtcccc actttcccct gagcctcagc acctgcttgt ttggaagggg tattgaatgt      300

gacatccgta tccagcttcc tgttgtgtca aaacaacatt gcaaaattga aatccatgag      360

caggaggcaa tattacataa tttcagttcc acaaatccaa cacaagtaaa tgggtctgtt      420

attgatgagc ctgtacggct aaaacatgga gatgtaataa ctattattga tcgttccttc      480

aggtatgaaa atgaaagtct tcagaatgga aggaagtcaa ctgaatttcc aagaaaaata      540

cgtgaacagg agccagcacg tcgtgtctca agatctagct tctcttctga ccctgatgag      600

agtgagggaa tacctttgaa aagaaggcgt gtgtcctttg gtgggcacct aagacctgaa      660

ctatttgatg aaaacttgcc tcctaatacg cctctcaaaa ggggagaagc cccaaccaaa      720

agaaagtctc tggtaatgca cactccacct gtcctgaaga aaatcatcaa ggaacagcct      780

caaccatcag gaaaacaaga gtcaggttca gaaatccatg tggaagtgaa ggcacaaagc      840

ttggttataa gccctccagc tcctagtcct aggaaaactc cagttgccag tgatcaacgc      900

cgtaggtcct gcaaaacagc ccctgcttcc agcagcaaat ctcagacaga ggttcctaag      960

agaggaggga gaaagagtgg caacctgcct tcaaagagag tgtctatcag ccgaagtcaa     1020

catgatattt tacagatgat atgttccaaa agaagaagtg gtgcttcgga agcaaatctg     1080

attgttgcaa aatcatgggc agatgtagta aaacttggtg caaaacaaac acaaactaaa     1140

gtcataaaac atggtcctca aaggtcaatg aacaaaaggc aaagaagacc tgctactcca     1200

aagaagcctg tgggcgaagt tcacagtcaa tttagtacag gccacgcaaa ctctccttgt     1260

accataataa tagggaaagc tcatactgaa aaagtacatg tgcctgctcg accctacaga     1320

gtgctcaaca acttcatttc caaccaaaaa atggacttta aggaagatct ttcaggaata     1380

gctgaaatgt tcaagacccc agtgaaggag caaccgcagt tgacaagcac atgtcacatc     1440

gctatttcaa attcagagaa tttgcttgga aaacagtttc aaggaactga ttcaggagaa     1500

gaacctctgc tccccacctc agagagtttt ggaggaaatg tgttcttcag tgcacagaat     1560

gcagcaaaac agccatctga taaatgctct gcaagccctc ccttaagacg gcagtgtatt     1620

agagaaaatg gaaacgtagc aaaaacgccc aggaacacct acaaaatgac ttctctggag     1680

acaaaaactt cagatactga gacagagcct tcaaaaacag tatccactgc aaacaggtca     1740

ggaaggtcta cagagttcag gaatatacag aagctacctg tggaaagtaa gagtgaagaa     1800

acaaatacag aaattgttga gtgcatccta aaaagaggtc agaaggcaac actactacaa     1860

caaaggagag aaggagagat gaaggaaata gaaagacctt ttgagacata taaggaaaat     1920

attgaattaa aagaaaacga tgaaaagatg aaagcaatga agagatcaag aacttggggg     1980

cagaaatgtg caccaatgtc tgacctgaca gacctcaaga gcttgcctga tacagaactc     2040

atgaaagaca cggcacgtgg ccagaatctc ctccaaaccc aagatcatgc caaggcacca     2100

aagagtgaga aaggcaaaat cactaaaatg ccctgccagt cattacaacc agaaccaata     2160

aacaccccaa cacacacaaa acaacagttg aaggcatccc tggggaaagt aggtgtgaaa     2220

gaagagctcc tagcagtcgg caagttcaca cggacgtcag gggagaccac gcacacgcac     2280

agagagccag caggagatgg caagagcatc agaacgttta aggagtctcc aaagcagatc     2340

ctggacccag cagcccgtgt aactggaatg aagaagtggc caagaacgcc taaggaagag     2400

gcccagtcac tagaagacct ggctggcttc aaagagctct tccagacacc aggtccctct     2460

gaggaatcaa tgactgatga gaaaactacc aaaatagcct gcaaatctcc accaccagaa     2520

tcagtggaca ctccaacaag cacaaagcaa tggcctaaga gaagtctcag gaaagcagat     2580

gtagaggaag aattcttagc actcaggaaa ctaacaccat cagcagggaa agccatgctt     2640

acgcccaaac cagcaggagg tgatgagaaa gacattaaag catttatggg aactccagtg     2700

cagaaactgg acctggcagg aactttacct ggcagcaaaa gacagctaca gactcctaag     2760

gaaaaggccc aggctctaga agacctggct ggctttaaag agctcttcca gactcctggt     2820

cacaccgagg aattagtggc tgctggtaaa accactaaaa taccctgcga ctctccacag     2880

tcagacccag tggacacccc aacaagcaca aagcaacgac ccaagagaag tatcaggaaa     2940

gcagatgtag agggagaact cttagcgtgc aggaatctaa tgccatcagc aggcaaagcc     3000

atgcacacgc ctaaaccatc agtaggtgaa gagaaagaca tcatcatatt tgtgggaact     3060

ccagtgcaga aactggacct gacagagaac ttaaccggca gcaagagacg gccacaaact     3120

cctaaggaag aggcccaggc tctggaagac ctgactggct ttaaagagct cttccagacc     3180

cctggtcata ctgaagaagc agtggctgct ggcaaaacta ctaaaatgcc ctgcgaatct     3240

tctccaccag aatcagcaga caccccaaca agcacaagaa ggcagcccaa gacacctttg     3300

gagaaaaggg acgtacagaa ggagctctca gccctgaaga agctcacaca gacatcaggg     3360

gaaaccacac acacagataa agtaccagga ggtgaggata aaagcatcaa cgcgtttagg     3420

gaaactgcaa aacagaaact ggacccagca gcaagtgtaa ctggtagcaa gaggcaccca     3480

aaaactaagg aaaaggccca acccctagaa gacctggctg gcttgaaaga gctcttccag     3540

acaccagtat gcactgacaa gcccacgact cacgagaaaa ctaccaaaat agcctgcaga     3600

tcacaaccag acccagtgga cacaccaaca agctccaagc cacagtccaa gagaagtctc     3660

aggaaagtgg acgtagaaga agaattcttc gcactcagga aacgaacacc atcagcaggc     3720

aaagccatgc acacacccaa accagcagta agtggtgaga aaaacatcta cgcatttatg     3780

ggaactccag tgcagaaact ggacctgaca gagaacttaa ctggcagcaa gagacggcta     3840

caaactccta aggaaaaggc ccaggctcta gaagacctgg ctggctttaa agagctcttc     3900

cagacacgag gtcacactga ggaatcaatg actaacgata aaactgccaa agtagcctgc     3960

aaatcttcac aaccagaccc agacaaaaac ccagcaagct ccaagcgacg gctcaagaca     4020

tccctgggga aagtgggcgt gaaagaagag ctcctagcag ttggcaagct cacacagaca     4080

tcaggagaga ctacacacac acacacagag ccaacaggag atggtaagag catgaaagca     4140

tttatggagt ctccaaagca gatcttagac tcagcagcaa gtctaactgg cagcaagagg     4200

cagctgagaa ctcctaaggg aaagtctgaa gtccctgaag acctggccgg cttcatcgag     4260

ctcttccaga caccaagtca cactaaggaa tcaatgacta acgaaaaaac taccaaagta     4320

tcctacagag cttcacagcc agacctagtg gacaccccaa caagctccaa gccacagccc     4380

aagagaagtc tcaggaaagc agacactgaa gaagaatttt tagcatttag gaaacaaacg     4440

ccatcagcag gcaaagccat gcacacaccc aaaccagcag taggtgaaga gaaagacatc     4500

aacacgtttt tgggaactcc agtgcagaaa ctggaccagc caggaaattt acctggcagc     4560

aatagacggc tacaaactcg taaggaaaag gcccaggctc tagaagaact gactggcttc     4620

agagagcttt tccagacacc atgcactgat aaccccacga ctgatgagaa aactaccaaa     4680

aaaatactct gcaaatctcc gcaatcagac ccagcggaca ccccaacaaa cacaaagcaa     4740

cggcccaaga gaagcctcaa gaaagcagac gtagaggaag aatttttagc attcaggaaa     4800

ctaacaccat cagcaggcaa agccatgcac acgcctaaag cagcagtagg tgaagagaaa     4860

gacatcaaca catttgtggg gactccagtg gagaaactgg acctgctagg aaatttacct     4920

ggcagcaaga gacggccaca aactcctaaa gaaaaggcca aggctctaga agatctggct     4980

ggcttcaaag agctcttcca gacaccaggt cacactgagg aatcaatgac cgatgacaaa     5040

atcacagaag tatcctgcaa atctccacaa ccagacccag tcaaaacccc aacaagctcc     5100

aagcaacgac tcaagatatc cttggggaaa gtaggtgtga aagaagaggt cctaccagtc     5160

ggcaagctca cacagacgtc agggaagacc acacagacac acagagagac agcaggagat     5220

ggaaagagca tcaaagcgtt taaggaatct gcaaagcaga tgctggaccc agcaaactat     5280

ggaactggga tggagaggtg gccaagaaca cctaaggaag aggcccaatc actagaagac     5340

ctggccggct tcaaagagct cttccagaca ccagaccaca ctgaggaatc aacaactgat     5400

gacaaaacta ccaaaatagc ctgcaaatct ccaccaccag aatcaatgga cactccaaca     5460

agcacaagga ggcggcccaa aacacctttg gggaaaaggg atatagtgga agagctctca     5520

gccctgaagc agctcacaca gaccacacac acagacaaag taccaggaga tgaggataaa     5580

ggcatcaacg tgttcaggga aactgcaaaa cagaaactgg acccagcagc aagtgtaact     5640

ggtagcaaga ggcagccaag aactcctaag ggaaaagccc aacccctaga agacttggct     5700

ggcttgaaag agctcttcca gacaccaata tgcactgaca agcccacgac tcatgagaaa     5760

actaccaaaa tagcctgcag atctccacaa ccagacccag tgggtacccc aacaatcttc     5820

aagccacagt ccaagagaag tctcaggaaa gcagacgtag aggaagaatc cttagcactc     5880

aggaaacgaa caccatcagt agggaaagct atggacacac ccaaaccagc aggaggtgat     5940

gagaaagaca tgaaagcatt tatgggaact ccagtgcaga aattggacct gccaggaaat     6000

ttacctggca gcaaaagatg gccacaaact cctaaggaaa aggcccaggc tctagaagac     6060

ctggctggct tcaaagagct cttccagaca ccaggcactg acaagcccac gactgatgag     6120

aaaactacca aaatagcctg caaatctcca caaccagacc cagtggacac cccagcaagc     6180

acaaagcaac ggcccaagag aaacctcagg aaagcagacg tagaggaaga atttttagca     6240

ctcaggaaac gaacaccatc agcaggcaaa gccatggaca caccaaaacc agcagtaagt     6300

gatgagaaaa atatcaacac atttgtggaa actccagtgc agaaactgga cctgctagga     6360

aatttacctg gcagcaagag acagccacag actcctaagg aaaaggctga ggctctagag     6420

gacctggttg gcttcaaaga actcttccag acaccaggtc acactgagga atcaatgact     6480

gatgacaaaa tcacagaagt atcctgtaaa tctccacagc cagagtcatt caaaacctca     6540

agaagctcca agcaaaggct caagataccc ctggtgaaag tggacatgaa agaagagccc     6600

ctagcagtca gcaagctcac acggacatca ggggagacta cgcaaacaca cacagagcca     6660

acaggagata gtaagagcat caaagcgttt aaggagtctc caaagcagat cctggaccca     6720

gcagcaagtg taactggtag caggaggcag ctgagaactc gtaaggaaaa ggcccgtgct     6780

ctagaagacc tggttgactt caaagagctc ttctcagcac caggtcacac tgaagagtca     6840

atgactattg acaaaaacac aaaaattccc tgcaaatctc ccccaccaga actaacagac     6900

actgccacga gcacaaagag atgccccaag acacgtccca ggaaagaagt aaaagaggag     6960

ctctcagcag ttgagaggct cacgcaaaca tcagggcaaa gcacacacac acacaaagaa     7020

ccagcaagcg gtgatgaggg catcaaagta ttgaagcaac gtgcaaagaa gaaaccaaac     7080

ccagtagaag aggaacccag caggagaagg ccaagagcac ctaaggaaaa ggcccaaccc     7140

ctggaagacc tggccggctt cacagagctc tctgaaacat caggtcacac tcaggaatca     7200

ctgactgctg gcaaagccac taaaataccc tgcgaatctc ccccactaga agtggtagac     7260

accacagcaa gcacaaagag gcatctcagg acacgtgtgc agaaggtaca agtaaaagaa     7320

gagccttcag cagtcaagtt cacacaaaca tcaggggaaa ccacggatgc agacaaagaa     7380

ccagcaggtg aagataaagg catcaaagca ttgaaggaat ctgcaaaaca gacaccggct     7440

ccagcagcaa gtgtaactgg cagcaggaga cggccaagag cacccaggga aagtgcccaa     7500

gccatagaag acctagctgg cttcaaagac ccagcagcag gtcacactga agaatcaatg     7560

actgatgaca aaaccactaa aataccctgc aaatcatcac cagaactaga agacaccgca     7620

acaagctcaa agagacggcc caggacacgt gcccagaaag tagaagtgaa ggaggagctg     7680

ttagcagttg gcaagctcac acaaacctca ggggagacca cgcacaccga caaagagccg     7740

gtaggtgagg gcaaaggcac gaaagcattt aagcaacctg caaagcggaa gctggacgca     7800

gaagatgtaa ttggcagcag gagacagcca agagcaccta aggaaaaggc ccaacccctg     7860

gaagatctgg ccagcttcca agagctctct caaacaccag gccacactga ggaactggca     7920

aatggtgctg ctgatagctt tacaagcgct ccaaagcaaa cacctgacag tggaaaacct     7980

ctaaaaatat ccagaagagt tcttcgggcc cctaaagtag aacccgtggg agacgtggta     8040

agcaccagag accctgtaaa atcacaaagc aaaagcaaca cttccctgcc cccactgccc     8100

ttcaagaggg gaggtggcaa agatggaagc gtcacgggaa ccaagaggct gcgctgcatg     8160

ccagcaccag aggaaattgt ggaggagctg ccagccagca agaagcagag ggttgctccc     8220

agggcaagag gcaaatcatc cgaacccgtg gtcatcatga agagaagttt gaggacttct     8280

gcaaaaagaa ttgaacctgc ggaagagctg aacagcaacg acatgaaaac caacaaagag     8340

gaacacaaat tacaagactc ggtccctgaa aataagggaa tatccctgcg ctccagacgc     8400

caaaataaga ctgaggcaga acagcaaata actgaggtct ttgtattagc agaaagaata     8460

gaaataaaca gaaatgaaaa gaagcccatg aagacctccc cagagatgga cattcagaat     8520

ccagatgatg gagcccggaa acccatacct agagacaaag tcactgagaa caaaaggtgc     8580

ttgaggtctg ctagacagaa tgagagctcc cagcctaagg tggcagagga gagcggaggg     8640

cagaagagtg cgaaggttct catgcagaat cagaaaggga aaggagaagc aggaaattca     8700

gactccatgt gcctgagatc aagaaagaca aaaagccagc ctgcagcaag cactttggag     8760

agcaaatctg tgcagagagt aacgcggagt gtcaagaggt gtgcagaaaa tccaaagaag     8820

gctgaggaca atgtgtgtgt caagaaaata agaaccagaa gtcataggga cagtgaagat     8880

atttgacaga aaaatcgaac tgggaaaaat ataataaagt tagttttgtg ataagttcta     8940

gtgcagtttt tgtcataaat tacaagtgaa ttctgtaagt aaggctgtca gtctgcttaa     9000

gggaagaaaa ctttggattt gctgggtctg aatcggcttc ataaactcca ctgggagcac     9060

tgctgggctc ctggactgag aatagttgaa caccgggggc tttgtgaagg agtctgggcc     9120

aaggtttgcc ctcagctttg cagaatgaag ccttgaggtc tgtcaccacc cacagccacc     9180

ctacagcagc cttaactgtg acacttgcca cactgtgtcg tcgtttgttt gcctatgtcc     9240

tccagggcac ggtggcagga acaactatcc tcgtctgtcc caacactgag caggcactcg     9300

gtaaacacga atgaatggat gagcgcacgg atgaatggag cttacaagat ctgtctttcc     9360

aatggccggg ggcatttggt ccccaaatta aggctattgg acatctgcac aggacagtcc     9420

tatttttgat gtcctttcct ttctgaaaat aaagttttgt gctttggaga atgactcgtg     9480

agcacatctt tagggaccaa gagtgacttt ctgtaaggag tgactcgtgg cttgccttgg     9540

tctcttggga atacttttct aactagggtt gctctcacct gagacattct ccacccgcgg     9600

aatctcaggg tcccaggctg tgggccatca cgacctcaaa ctggctccta atctccagct     9660

ttcctgtcat tgaaagcttc ggaagtttac tggctctgct cccgcctgtt ttctttctga     9720

ctctatctgg cagcccgatg ccacccagta caggaagtga caccagtact ctgtaaagca     9780

tcatcatcct tggagagact gagcactcag caccttcagc cacgatttca ggatcgcttc     9840

cttgtgagcc gctgcctccg aaatctcctt tgaagcccag acatctttct ccagcttcag     9900

acttgtagat ataactcgtt catcttcatt tactttccac tttgccccct gtcctctctg     9960

tgttccccaa atcagagaat agcccgccat cccccaggtc acctgtctgg attcctcccc    10020

attcacccac cttgccaggt gcaggtgagg atggtgcacc agacagggta gctgtccccc    10080

aaaatgtgcc ctgtgcgggc agtgccctgt ctccacgttt gtttccccag tgtctggcgg    10140

ggagccaggt gacatcataa atacttgctg aatgaatgca gaaatcagcg gtactgactt    10200

gtactatatt ggctgccatg atagggttct cacagcgtca tccatgatcg taagggagaa    10260

tgacattctg cttgagggag ggaatagaaa ggggcaggga ggggacatct gagggcttca    10320

cagggctgca aagggtacag ggattgcacc agggcagaac aggggagggt gttcaaggaa    10380

gagtggctct tagcagaggc actttggaag gtgtgaggca taaatgcttc cttctacgta    10440

ggccaacctc aaaactttca gtaggaatgt tgctatgatc aagttgttct aacactttag    10500

acttagtagt aattatgaac ctcacataga aaaatttcat ccagccatat gcctgtggag    10560

tggaatattc tgtttagtag aaaaatcctt tagagttcag ctctaaccag aaatcttgct    10620

gaagtatgtc agcacctttt ctcaccctgg taagtacagt atttcaagag cacgctaagg    10680

gtggttttca ttttacaggg ctgttgatga tgggttaaaa atgttcattt aagggctacc    10740

cccgtgttta atagatgaac accacttcta cacaaccctc cttggtactg ggggagggag    10800

agatctgaca aatactgccc attcccctag gctgactgga tttgagaaca aatacccacc    10860

catttccacc atggtatggt aacttctctg agcttcagtt tccaagtgaa tttccatgta    10920

ataggacatt cccattaaat acaagctgtt tttacttttt cgcctcccag ggcctgtggg    10980

atctggtccc ccagcctctc ttgggctttc ttacactaac tctgtaccta ccatctcctg    11040

cctcccttag gcaggcacct ccaaccacca cacactccct gctgttttcc ctgcctggaa    11100

ctttccctcc tgccccacca agatcatttc atccagtcct gagctcagct taagggaggc    11160

ttcttgcctg tgggttccct cacccccatg cctgtcctcc aggctggggc aggttcttag    11220

tttgcctgga attgttctgt acctctttgt agcacgtagt gttgtggaaa ctaagccact    11280

aattgagttt ctggctcccc tcctggggtt gtaagttttg ttcattcatg agggccgact    11340

gcatttcctg gttactctat cccagtgacc agccacagga gatgtccaat aaagtatgtg    11400

atgaaatggt cttaaaaaaa aaaaaaa                                        11427


<210>  686
<211>  2724
<212>  DNA
<213>  homo sapiens

<400>  686
gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt       60

ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt      120

gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca      180

gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc      240

tctgagtcag gaaacatttt cagacctatg gaaactactt cctgaaaaca acgttctgtc      300

ccccttgccg tcccaagcaa tggatgattt gatgctgtcc ccggacgata ttgaacaatg      360

gttcactgaa gacccaggtc cagatgaagc tcccagaatg ccagaggctg ctccccccgt      420

ggcccctgca ccagcagctc ctacaccggc ggcccctgca ccagccccct cctggcccct      480

gtcatcttct gtcccttccc agaaaaccta ccagggcagc tacggtttcc gtctgggctt      540

cttgcattct gggacagcca agtctgtgac ttgcacgtac tcccctgccc tcaacaagat      600

gttttgccaa ctggccaaga cctgccctgt gcagctgtgg gttgattcca cacccccgcc      660

cggcacccgc gtccgcgcca tggccatcta caagcagtca cagcacatga cggaggttgt      720

gaggcgctgc ccccaccatg agcgctgctc agatagcgat ggtctggccc ctcctcagca      780

tcttatccga gtggaaggaa atttgcgtgt ggagtatttg gatgacagaa acacttttcg      840

acatagtgtg gtggtgccct atgagccgcc tgaggttggc tctgactgta ccaccatcca      900

ctacaactac atgtgtaaca gttcctgcat gggcggcatg aaccggaggc ccatcctcac      960

catcatcaca ctggaagact ccagtggtaa tctactggga cggaacagct ttgaggtgcg     1020

tgtttgtgcc tgtcctggga gagaccggcg cacagaggaa gagaatctcc gcaagaaagg     1080

ggagcctcac cacgagctgc ccccagggag cactaagcga gcactgccca acaacaccag     1140

ctcctctccc cagccaaaga agaaaccact ggatggagaa tatttcaccc ttcaggacca     1200

gaccagcttt caaaaagaaa attgttaaag agagcatgaa aatggttcta tgactttgcc     1260

tgatacagat gctacttgac ttacgatggt gttacttcct gataaactcg tcgtaagttg     1320

aaaatattat ccgtgggcgt gagcgcttcg agatgttccg agagctgaat gaggccttgg     1380

aactcaagga tgcccaggct gggaaggagc caggggggag cagggctcac tccagccacc     1440

tgaagtccaa aaagggtcag tctacctccc gccataaaaa actcatgttc aagacagaag     1500

ggcctgactc agactgacat tctccacttc ttgttcccca ctgacagcct cccaccccca     1560

tctctccctc ccctgccatt ttgggttttg ggtctttgaa cccttgcttg caataggtgt     1620

gcgtcagaag cacccaggac ttccatttgc tttgtcccgg ggctccactg aacaagttgg     1680

cctgcactgg tgttttgttg tggggaggag gatggggagt aggacatacc agcttagatt     1740

ttaaggtttt tactgtgagg gatgtttggg agatgtaaga aatgttcttg cagttaaggg     1800

ttagtttaca atcagccaca ttctaggtag gggcccactt caccgtacta accagggaag     1860

ctgtccctca ctgttgaatt ttctctaact tcaaggccca tatctgtgaa atgctggcat     1920

ttgcacctac ctcacagagt gcattgtgag ggttaatgaa ataatgtaca tctggccttg     1980

aaaccacctt ttattacatg gggtctagaa cttgaccccc ttgagggtgc ttgttccctc     2040

tccctgttgg tcggtgggtt ggtagtttct acagttgggc agctggttag gtagagggag     2100

ttgtcaagtc tctgctggcc cagccaaacc ctgtctgaca acctcttggt gaaccttagt     2160

acctaaaagg aaatctcacc ccatcccaca ccctggagga tttcatctct tgtatatgat     2220

gatctggatc caccaagact tgttttatgc tcagggtcaa tttctttttt cttttttttt     2280

tttttttttc tttttctttg agactgggtc tcgctttgtt gcccaggctg gagtggagtg     2340

gcgtgatctt ggcttactgc agcctttgcc tccccggctc gagcagtcct gcctcagcct     2400

ccggagtagc tgggaccaca ggttcatgcc accatggcca gccaactttt gcatgttttg     2460

tagagatggg gtctcacagt gttgcccagg ctggtctcaa actcctgggc tcaggcgatc     2520

cacctgtctc agcctcccag agtgctggga ttacaattgt gagccaccac gtccagctgg     2580

aagggtcaac atcttttaca ttctgcaagc acatctgcat tttcacccca cccttcccct     2640

ccttctccct ttttatatcc catttttata tcgatctctt attttacaat aaaactttgc     2700

tgccacctgt gtgtctgagg ggtg                                            2724


<210>  687
<211>  9960
<212>  DNA
<213>  homo sapiens

<400>  687
ctgagtgctg tccaggaggc ccagttaaag cggctcgagg tgacaagacc ccgagtgctg       60

gggagcaggg agcagggcca ggtgccgagg atggccaggc agccaccgcc gccctgggtc      120

catgcagcct tcctcctctg cctcctcagt cttggcggag ccatcgaaat tcctatggat      180

ctgacgcagc cgccaaccat caccaagcag tcagcgaagg atcacatcgt ggacccccgt      240

gataacatcc tgattgagtg tgaagcaaaa gggaaccctg cccccagctt ccactggaca      300

cgaaacagca gattcttcaa catcgccaag gacccccggg tgtccatgag gaggaggtct      360

gggaccctgg tgattgactt ccgcagtggc gggcggccgg aggaatatga gggggaatat      420

cagtgcttcg cccgcaacaa atttggcacg gccctgtcca ataggatccg cctgcaggtg      480

tctaaatctc ctctgtggcc caaggaaaac ctagaccctg tcgtggtcca agagggcgct      540

cctttgacgc tccagtgcaa ccccccgcct ggacttccat ccccggtcat cttctggatg      600

agcagctcca tggagcccat cacccaagac aaacgtgtct ctcagggcca taacggagac      660

ctatacttct ccaacgtgat gctgcaggac atgcagaccg actacagttg taacgcccgc      720

ttccacttca cccacaccat ccagcagaag aaccctttca ccctcaaggt cctcaccaac      780

cacccttata atgactcgtc cttaagaaac caccctgaca tgtacagtgc ccgaggagtt      840

gcagaaagaa caccaagctt catgtatccc cagggcaccg cgagcagcca gatggtgctt      900

cgtggcatgg acctcctgct ggaatgcatc gcctccgggg tcccaacacc agacatcgca      960

tggtacaaga aaggtgggga cctcccatct gataaggcca agtttgagaa ctttaataag     1020

gccctgcgta tcacaaatgt ctctgaggaa gactccgggg agtatttctg cctggcctcc     1080

aacaagatgg gcagcatccg gcacacgatc tcggtgagag taaaggctgc tccctactgg     1140

ctggacgaac ccaagaacct tattctggct cctggcgagg atgggagact ggtgtgtcga     1200

gccaatggaa accccaaacc cactgtccag tggatggtga atggggaacc tttgcaatcg     1260

gcaccaccta acccaaaccg tgaggtggcc ggagacacca tcatcttccg ggacacccag     1320

atcagcagca gggctgtgta ccagtgcaac acctccaacg agcatggcta cctgctggcc     1380

aacgcctttg tcagtgtgct ggatgtgccg cctcggatgc tgtcgccccg gaaccagctc     1440

attcgagtga ttctttacaa ccggacgcgg ctggactgcc ctttctttgg gtctcccatc     1500

cccacactgc gatggtttaa gaatgggcaa ggaagcaacc tggatggtgg caactaccat     1560

gtttatgaga acggcagtct ggaaattaag atgatccgca aagaggacca gggcatctac     1620

acctgtgtcg ccaccaacat cctgggcaaa gctgaaaacc aagtccgcct ggaggtcaaa     1680

gaccccacca ggatctaccg gatgcccgag gaccaggtgg ccagaagggg caccacggtg     1740

cagctggagt gtcgggtgaa gcacgacccc tccctgaaac tcaccgtctc ctggctgaag     1800

gatgacgagc cgctctatat tggaaacagg atgaagaagg aagacgactc cctgaccatc     1860

tttggggtgg cagagcggga ccagggcagt tacacgtgtg tcgccagcac cgagctagac     1920

caagacctgg ccaaggccta cctcaccgtg ctagctgatc aggccactcc aactaaccgt     1980

ttggctgccc tgcccaaagg acggccagac cggccccggg acctggagct gaccgacctg     2040

gccgagagga gcgtgcggct gacctggatc cccggggatg ctaacaacag ccccatcaca     2100

gactacgtcg tccagtttga agaagaccag ttccaacctg gggtctggca tgaccattcc     2160

aagtaccccg gcagcgttaa ctcagccgtc ctccggctgt ccccgtatgt caactaccag     2220

ttccgtgtca ttgccatcaa cgaggttggg agcagccacc ccagcctccc atccgagcgc     2280

taccgaacca gtggagcacc ccccgagtcc aatcctggtg acgtgaaggg agaggggacc     2340

agaaagaaca acatggagat cacgtggacg cccatgaatg ccacctcggc ctttggcccc     2400

aacctgcgct acattgtcaa gtggaggcgg agagagactc gagaggcctg gaacaacgtc     2460

acagtgtggg gctctcgcta cgtggtgggg cagaccccag tctacgtgcc ctatgagatc     2520

cgagtccagg ctgaaaatga cttcgggaag ggccctgagc cagagtccgt catcggttac     2580

tccggagaag attatcccag ggctgcgccc actgaagtta aagtccgagt catgaacagc     2640

acagccatca gccttcagtg gaaccgcgtc tactccgaca cggtccaggg ccagctcaga     2700

gagtaccgag cctactactg gagggagagc agcttgctga agaacctgtg ggtgtctcag     2760

aagagacagc aagccagctt ccctggtgac cgcctccgtg gcgtggtgtc ccgcctcttc     2820

ccctacagta actacaagct ggagatggtt gtggtcaatg ggagaggtga tgggcctcgc     2880

agtgagacca aggagttcac caccccggaa ggagtaccca gtgcccctag gcgtttccga     2940

gtccggcagc ccaacctgga gacaatcaac ctggaatggg atcatcctga gcatccaaat     3000

gggatcatga ttggatacac tctcaaatat gtggccttta acgggaccaa agtaggaaag     3060

cagatagtgg aaaacttctc tcccaatcag accaagttca cggtgcaaag aacggacccc     3120

gtgtcacgct accgctttac cctcagcgcc aggacgcagg tgggctctgg ggaagccgtc     3180

acagaggagt caccagcacc cccgaatgaa gctactccaa ccgcagctta caccaacaac     3240

caagcggaca tcgccaccca gggctggttc attgggctta tgtgcgccat cgccctcctg     3300

gtgctgatcc tgctcatcgt ctgtttcatc aagaggagtc gcggcggcaa gtacccagta     3360

cgagaaaaga aggatgttcc ccttggccct gaagacccca aggaagagga tggctcattt     3420

gactatagtg atgaggacaa caagcccctg cagggcagtc agacatctct ggacggcacc     3480

atcaagcagc aggagagtga cgacagcctg gtggactatg gcgagggtgg cgagggtcag     3540

ttcaatgaag acggctcctt catcggccag tacacggtca aaaaggacaa ggaggaaaca     3600

gagggcaacg aaagctcaga ggccacgtca cctgtcaatg ctatctactc tctggcctaa     3660

cggagcccac ccaggcacag ccaccacttt gcaagtggga ggaggggaga aggggagaca     3720

aaaccactgc agacctacca cgaagccacc accaccttca gtaacaaggg tacgatatgg     3780

gggtctgcca agctgtgagg accagtagcc accaagccac ccacaagccc cctcccaatg     3840

accccccttc agccccgggt gccaccagtg tgggagagct ggagccgtgg ctgagctcag     3900

ctggagggag cctggcccct tgcccggtct cgcagccacc ccgagcgttc caccacactg     3960

tccgcccttg gcctcggcac acgctcacct tttctgttgg ttacgggact tctcattgtc     4020

ttaatttcgc tttgtgcatc ttcccctcca gacccaatgt ctctgttttc ttttcctttt     4080

gaaaaagagt ccctggaaaa gaaagaataa gtggattctc ccccaggaga atcctttttg     4140

caaagatagg caaaaaggat tgaatccata ccagaacacg tagacaggct gtaatattca     4200

aaccacctct gggccaatgc atttccaaag gatgcctttc tcgccatatg cctcccctgg     4260

cccccagccc ctctgcctcg gccttgtcag ttgctgagct gggcttggct cctttctgga     4320

aaatgacagt atttttggca gggagaaggt gcgcaggcct ccttgctgct ctctggtttg     4380

gttgggaggt gtgtttacct cttgctcctc attcctcccc tgcccttttc tctggaatat     4440

ctaagatgtg agctgcattg actctgaaga cgtttgagga acaggagtgg gcactgatag     4500

aaaggacttc aacgccagtg actgtgtacc tccagcagaa gaaaatcagg tgtctggtct     4560

tgggggcact gtgctcactt ctagagagaa gaaaaaggct gggtttggac ttcatgcctc     4620

ctcactggtg aaacccagga tgtagataga gggccacacc caccctgtcc agagtagagg     4680

gcacctgtcc acgtggccag ggcccatgct gccaccctcg aggagatgga accctgtgat     4740

gcaaaagctt tgctggtgtg tttggggcat aaggcactgc tccccttcca tctctagcag     4800

atatcatctt ctcagccaat tctgtaggac actgaggctc ttgtttgaca tggtgtgtgg     4860

atggggactt gccccaagac tgagcaggtc tgccctttca ttggggtgta tacatatcag     4920

gggaccctga ggtggcaccg tactcagtgt tgtgatgccc ccacctaggg aggactcaat     4980

gctctttgta tgccttatgc agcgctgatc tgtccctgga gttcccaggt tcccagctcc     5040

ccccctgcaa gccttgaagc ctccagcaac gtctatctcc aggagagcag ggcagcctat     5100

gcaagtgttc cggcaggacc agaagtggcc actcaacaca cgtcctcacc agtcacccca     5160

aatggagaca ctcgcagacc tgcagttctc agaccgaagg tgctgccttc atcctcccca     5220

cctaatgcat ttttgaaacc aaaggtacct agcctcagag acagagaagg agagggggag     5280

atcttgagtc taagaggaac cctttagctg tttctgcagc tgaggtcagt ttcaggaggg     5340

tgaagctgat ccccaggaat ggatcagctg ccatgggcac agcctccgat ttgagcctct     5400

ccggctgcca gccagggggc ctgggccaga ccagggctct gtccttccgt gactttatta     5460

aagcaacatt tgccacatgt ttaagccgca aaggtattag caatgcttgc atcattaata     5520

atcattcagt tgaaggtcaa gcccatagac acacactctc tgctggtaag aaaccatagc     5580

ccagaactga gccaataagg ttgtttgaac ctgagagtgt gtaatggtca tttgggccaa     5640

gcctcagcta gggctgctgc ctggacgcct gaggggcagc ttatcacagt gcaaggggac     5700

agggtaaaca gcagggggtg gggtgtgagc ttggagggcc cctcccctgg atttcctcca     5760

acacctgctt ggatactagg cccactgtcc ctgaagggaa tgtcagggaa gtgtgcctgt     5820

gagctgaatt aaaggactgg cctttccaga aaacgctttg gatctgagca gagtagtcag     5880

tttctcagac actcattcca tactgcaccg tacatgccag cgtacccatt gcaccgaaag     5940

caggccctta gggcaggaag ggacgatgag caagtctgcc acaccacctg gtgactggga     6000

agggctgctt ctctcgtaag ggtcttgggg agaagtaagc ccgcagcctg cctctgcacc     6060

tcgttccagt gtcctgccag gctctgtact gtcctttgtg tatgaagaaa atgctgttag     6120

ccctctctca ggctgctgtt ctgtgggtgc tgagagctgc cccccatcac cacgccatca     6180

cacccctctg agcagaagca aatctgaggc tgaagaatta agttttcccc aagcaaggaa     6240

ggcaggtggt cagagagatc aaacgctgag gcgtggggat tgcaggattc aggaggcagc     6300

ccctttgggg aagaggaggg tgcattttcc atggagccca tgtcagagtc cactccagct     6360

cagcaggaaa gtggaattgc ccagtactgc ctgccagctg ggtctcccaa gcaactaccc     6420

caagacatac caacagtgaa gccaggacag caccatgcca tcggcgctcc agtctgtctg     6480

gctgggagga aagtgctggg catcttacag taactctaga agttcctttg actaggctgc     6540

aatcccacct atatgctcag ccctaagagc tgtggtttcc tgtgctctca tttgtccatt     6600

cattcattca ttcattcatt cagcaaataa tctgaaatcc agtctgaact aaggcctgag     6660

ctgtggatac catggcgcgt gagttagatg tggtccctgc cctcatgggg ctgacagtcc     6720

taaaatcaag tgctaggaca cagtggccat tgagctggga gcattcttcc ctctaccgct     6780

taagccactg atggctgcga gcttgaagag agggattctg agggagagct tggtccatct     6840

ggtcaccaag gctgggcggg acagagcagt caagaaccac ggtgtggctt gagaaacagt     6900

cctgcttcct gagcctcttt gctctgcctc ttggggcaag ctccttaacc tgtctgtatt     6960

tttatgcctc tgtctcccat tcagttcctc cttgaatacc tctttctaca gagaggcacg     7020

ggctcccctg aaggattgtc gaggccaggg ttcgggaagt acactgccat cggtcagggg     7080

acagctgcct cccaccttgc ctgggtgatg gtgaatggga ctcatctttt cctgccttgc     7140

ttttgaggag atggttgaat ttaagctaac aggaaagcca aaccagcacc ctcctttgtg     7200

ctctgagagg ttggagacat ctggtccacc ccattgcccc tgcccctggc aagccctgaa     7260

gtcgggagag gtgaccacag gtctgaaaat cagccagtgc caacattgct tgccctgcaa     7320

ggtgcaactg agcccacata gcgcattcat agtttccctg accacagcct tgggaagacg     7380

gtggaaaccc gaggatgtgt gggtttccca gctaacggac aagctcccct gccacaccca     7440

gtgcccacgc atgctcacat acatacagca gaccacaacc ctgttgccaa gcagtgcttc     7500

caagggatag cgatccagat tccaacattg tcttggagag ggttagtcca catccaagtt     7560

gcgtgagata agatgcaaag ggctctgtgt ggatgaggaa cgcaccttag aggagtggga     7620

aaggccacca gggttgggcc ctgtttaggt aattcctgtt ggcagcacct agagagagca     7680

tctgagctga aggagtggga aactttgccc aagcaatggc acgggcagcg ggctctttct     7740

ggcgccctgt gctggagcag ggccaagtct tagggcatca caaacagccc atttgatgga     7800

gggagcaggg acatagcaca tttttgtctg tctttgtgag gctgctttgc taactctctg     7860

aggagaggaa gcctctcggg ctttccgtcg gctggggcta gtgccagaga atcccttctc     7920

agtggccagc aggttcctgg gaggccggca caaggcaccg ctccccactc atgacacctt     7980

ggtgcagagt gacctcctgc ccagtcacca ctccggccag ccccagccaa acacacaaaa     8040

gcccatggtt gcggttgcat ctacaccgtt agttggcaaa ggatcctgct tgagctctgc     8100

gtggtggcca aggagtagca tggaggaggg ccctgatttt aaaaaggaaa aatagagagg     8160

cctcaaaaca atgaaacaaa gagcttgata tgtcaagagg agaccaaggc cctgggaggc     8220

ataggcaagc cgggcagagt cagaccagtg ccctcccttg accatctcct agcattcctt     8280

aacctagaca ggggctaccc catgtgagtc caagccagac tttgtggctg tccccagcct     8340

gcacagccca agcccaggga agtgtccttt ctttcccttc cttactaata atgggccttc     8400

ctgagacaca ttcagagaag gatcagagag aaaggagaac catccaggag agccacaagc     8460

gtccaccaaa cagtgtctca ggcctcacct gaagctgctg ttcctcctat cagcacacta     8520

gtattaaatg ggtgttccat aatgaggaga atggaaatag gtacaaggca tctagcttag     8580

gacagaatcg gatttcggca tgtgaaggaa tcccagagct gatctcattg aaatgatcta     8640

tcgtacagac aaggatatgc aaatccacag aagtgaaggg atttttgctc aagatcacat     8700

agctggtaaa ctaaggtaag gttagggctt gaacttgggc cttctgactc cttgtccagt     8760

cagtgttctt tcatctcacc acagctgcct cctttgaaac agaggtatta agatctgtcc     8820

ttctggttca ccctctcata cctctttact gcgtctccca catcccccac atgcctccca     8880

aaatgaaaga caaacaggat tgtttctgag accaagatca gtctgtctgt gatcagcctg     8940

tgtgtggttc acccagtcat gcaattaagg gcagatctgg gccagtggaa taggatagct     9000

gattggtgtt tgttactgtg aaccctagac cgtaccccgt agaatggtgt ctcttgcttt     9060

gtaacacatc gggccttcag tgtgctgtat tcctcagaag tgagggcatc tcggtccatt     9120

ctgcccatgg ccacagggtg cagagaggca gcagggccca tgcaagctgc caccctggga     9180

tttgctgggc tggagttcaa cagatgtaaa gacttcagtg aagcaataaa cacaaaactc     9240

tgggagaaga tatccagaat tttgtacatt actctgtttc tttttcaaaa atgaggcaga     9300

tcagatgccc ctgagctgcc cctttttttc tgattcccaa ctgcaatgtc ctcagtcagt     9360

gttgtccctc tgcccggctc cccagctctt tgccaacctc ttcacactcc ccttgagctg     9420

agcatcagtc gcctgtgacg tggccacctt ctgtcctgct cccactcccg acccatgctg     9480

gaccccggag gacctcctgc cccgccccca ccacacaccc atatccccca ccattccaat     9540

ttgttctttc ccgtggggaa ttttttttcc cagcgtctcc atcccttcct acatatccac     9600

acacacacaa attggtctga tcttttttcc attggttaaa catttaactc catgccagac     9660

cttgttttaa cccctctcac atcatgttct ttcctttttt gcgagttatt ttgcattaac     9720

caactttgtc agtgacagat gcgtatctga gggtgtcaca cacgaccttc agcagggaag     9780

acttctgggc catggagggc cgtctaatac atggacttat aaactgactg catgagcaat     9840

gaaaaggcca aattattctg aatttttttt gaatcactgt aaaaaaactg atttcttttg     9900

tatagagaac actaaacgta taataaaagt tgttcaaaat ggaaaaaaaa aaaaaaaaaa     9960


<210>  688
<211>  2166
<212>  DNA
<213>  homo sapiens

<400>  688
aaaagaccac gtggggacgc ggtggggcgg gtctggcggg ggcggggcac ctctgtgcag       60

ggttcccagt caccgcgacg ctcctcggga agccataggg cgcctcccag cccgtctccc      120

cgctccagtt tagaacctaa ttcccaattc ccggaccggg cccagccctg ggctcttact      180

gtccgctttt gctgggacct gttccacaaa tgggcgtctt ctgccttggg ccgtgggggt      240

tgggccggaa gctgcggacg cctgggaagg ggccgctgca gctcttgagc cgcctctgcg      300

gggaccactt gcaggccatc ccagccaaga aggccccggc tgggcaggag gagcctggga      360

cgccgccctc ctcgccgctg agtgccgagc agttggaccg gatccagagg aacaaggccg      420

cggccctgct cagactcgcg gcccgcaacg tgcccgtggg ctttggagag agctggaaga      480

agcacctcag cggggagttc gggaaaccgt attttatcaa gctaatggga tttgttgcag      540

aagaaagaaa gcattacact gtttatccac ccccacacca agtcttcacc tggacccaga      600

tgtgtgacat aaaagatgtg aaggttgtca tcctgggaca ggatccatat catggaccta      660

atcaagctca cgggctctgc tttagtgttc aaaggcctgt tccgcctccg cccagtttgg      720

agaacattta taaagagttg tctacagaca tagaggattt tgttcatcct ggccatggag      780

atttatctgg gtgggccaag caaggtgttc tccttctcaa cgctgtcctc acggttcgtg      840

cccatcaagc caactctcat aaggagcgag gctgggagca gttcactgat gcagttgtgt      900

cctggctaaa tcagaactcg aatggccttg ttttcttgct ctggggctct tatgctcaga      960

agaagggcag tgccattgat aggaagcggc accatgtact acagacggct catccctccc     1020

ctttgtcagt gtatagaggg ttctttggat gtagacactt ttcaaagacc aatgagctgc     1080

tgcagaagtc tggcaagaag cccattgact ggaaggagct gtgatcatca gctgaggggt     1140

ggcctttgag aagctgctgt taacgtattt gccagttacg aagttccact gaaaattttc     1200

ctattaattc ttaagtactc tgcataaggg ggaaaagctt ccagaaagca gccatgaacc     1260

aggctgtcca ggaatggcag ctgtatccaa ccacaaacaa caaaggctac cctttgacca     1320

aatgtctttc tctgcaacat ggcttcggcc taaaatatgc agaagacaga tgaggtcaaa     1380

tactcagttg gctctcttta tctcccttgc ctttatggtg aaacagggga gatgtgcacc     1440

tttcaggcac agccctagtt tggcgcctgc tgctccttgg ttttgcctgg ttagactttc     1500

agtgacagat gttggggtgt ttttgcttag aaaggtcccc ttgtctcagc cttgcagggc     1560

aggcatgcca gtctctgcca gttccactgc ccccttgatc tttgaaggag tcctcaggcc     1620

cctcgcagca taaggatgtt ttgcaacttt ccagaatctg gcccagaaat tagggctcaa     1680

tttcctgatt gtagtagagg ttaagattgc tgtgagcttt atcagataag agaccgagag     1740

aagtaagctg ggtcttgtta ttccttgggt gttggtggaa taagcagtgg aatttgaaca     1800

aggaagagga gaaaagggaa ttttgtcttt atggggtggg gtgattttct cctagggtta     1860

tgtccagttg gggtttttaa ggcagcacag actgccaagt actgtttttt ttaaccgact     1920

gaaatcactt tgggatattt tttcctgcaa cactggaaag ttttagtttt ttaagaagta     1980

ctcatgcaga tatatatata tatatttttc ccagtccttt ttttaagaga cggtctttat     2040

tgggtctgca cctccatcct tgatcttgtt agcaatgctg tttttgctgt tagtcgggtt     2100

agagttggct ctacgcgagg tttgttaata aaagtttgtt aaaagtttaa aaaaaaaaaa     2160

aaaaaa                                                                2166


<210>  689
<211>  4698
<212>  DNA
<213>  homo sapiens

<400>  689
cttgcgcact gagaactcac accatatgtg tcctgttcca gtgcgcgggt ctgtggagag       60

ccgggtgcga gcggcggcag cacgagggga aaagagctga gcggagacca aagtcagccg      120

ggagacagtg ggtctgtgag agaccgaata gaggggctgg ggccacgagc gccattgaca      180

agcaatgggg aagaaacaga aaaacaagag cgaagacagc accaaggatg acattgatct      240

tgatgccttg gctgcagaaa tagaaggagc tggtgctgcc aaagaacagg agcctcaaaa      300

gtcaaaaggg aaaaagaaaa aagagaaaaa aaagcaggac tttgatgaag atgatatcct      360

gaaagaactg gaagaattgt ctttggaagc tcaaggcatc aaagctgaca gagaaactgt      420

tgcagtgaag ccaacagaaa acaatgaaga ggaattcacc tcaaaagata aaaaaaagaa      480

aggacagaag ggcaaaaaac agagttttga tgataatgat agcgaagaat tggaagataa      540

agattcaaaa tcaaaaaaga ctgcaaaacc gaaagtggaa atgtactctg ggagtgatga      600

tgatgatgat tttaacaaac ttcctaaaaa agctaaaggg aaagctcaaa aatcaaataa      660

gaagtgggat gggtcagagg aggatgagga taacagtaaa aaaattaaag agcgttcaag      720

aataaattct tctggtgaaa gtggtgatga atcagatgaa tttttgcaat ctagaaaagg      780

acagaaaaaa aatcagaaaa acaagccagg tcctaacata gaaagtggga atgaagatga      840

tgacgcctcc ttcaaaatta agacagtggc ccaaaagaag gcagaaaaga aggagcgcga      900

gagaaaaaag cgagatgaag aaaaagcgaa actgcggaag ctgaaagaaa aagaagagtt      960

agaaacaggt aaaaaggatc agagtaaaca aaaggaatct caaaggaaat ttgaagaaga     1020

aactgtaaaa tccaaagtga ctgttgatac tggagtaatt cctgcctctg aagagaaagc     1080

agagactccc acagctgcag aagatgacaa tgaaggagac aaaaagaaga aagataagaa     1140

gaaaaagaaa ggagaaaagg aagaaaaaga gaaagagaag aaaaaaggac ctagcaaagc     1200

cactgttaaa gctatgcaag aagctctggc taagcttaaa gaggaagaag aaagacagaa     1260

gagagaagag gaagaacgta taaaacggct tgaagaatta gaagccaagc gtaaagaaga     1320

ggaacgattg gaacaagaaa aaagagaaag gaaaaagcaa aaagaaaaag aaagaaaaga     1380

acgcttgaaa aaagaaggga aacttttaac taaatcccag agagaagcca gagccagagc     1440

cgaagctact cttaaactgc tacaagctca gggtgttgaa gtgccatcaa aagactcttt     1500

gccaaagaag aggccaattt atgaagataa aaagaggaaa aaaataccac agcagctaga     1560

aagtaaagaa gtgtctgaat caatggaatt atgtgctgct gtagaagtta tggaacaagg     1620

agtaccagaa aaggaagaga caccacctcc tgttgaacca gaagaagaag aagatactga     1680

ggatgctgga ttggatgatt gggaagctat ggccagtgat gaggagacag aaaaagtaga     1740

aggaaacaaa gttcatatag aagtaaaaga aaaccctgaa gaggaggagg aggaggaaga     1800

agaggaagaa gaagatgaag aaagtgaaga agaggaggaa gaggagggag aaagtgaagg     1860

cagtgaaggt gatgaggaag atgaaaaggt gtcagatgag aaggattcag ggaagacatt     1920

agataaaaag ccaagtaaag aaatgagctc agattctgaa tatgactctg atgatgatcg     1980

gactaaagaa gaaagggctt atgacaaagc aaaacggagg attgagaaac ggcgacttga     2040

acatagtaaa aatgtaaaca ccgaaaagct aagagcccct attatctgcg tacttgggca     2100

tgtggacaca gggaagacaa aaattctaga taagctccgt cacacacatg tacaagatgg     2160

tgaagcaggt ggtatcacac aacaaattgg ggccaccaat gttcctcttg aagctattaa     2220

tgaacagact aagatgatta aaaattttga tagagagaat gtacggattc caggaatgct     2280

aattattgat actcctgggc atgaatcttt cagtaatctg agaaatagag gaagctctct     2340

ttgtgacatt gccattttag ttgttgatat tatgcatggt ttggagcccc agacaattga     2400

gtctatcaac cttctcaaat ctaaaaaatg tcccttcatt gttgcactca ataagattga     2460

taggttatat gattggaaaa agagtcctga ctctgatgtg gctgctactt taaagaagca     2520

gaaaaagaat acaaaagatg aatttgagga gcgagcaaag gctattattg tagaatttgc     2580

acagcagggt ttgaatgctg ctttgtttta tgagaataaa gatccccgca cttttgtgtc     2640

tttggtacct acctctgcac atactggtga tggcatggga agtctgatct accttcttgt     2700

agagttaact cagaccatgt tgagcaagag acttgcacac tgtgaagagc tgagagcaca     2760

ggtgatggag gttaaagctc tcccggggat gggcaccact atagatgtca tcttgatcaa     2820

tgggcgtttg aaggaaggag atacaatcat tgttcctgga gtagaagggc ccattgtaac     2880

tcagattcga ggcctcctgt tacctcctcc tatgaaggaa ttacgagtga agaaccagta     2940

tgaaaagcat aaagaagtag aagcagctca gggggtaaag attcttggaa aagacctgga     3000

gaaaacattg gctggtttac ccctccttgt ggcttataaa gaagatgaaa tccctgttct     3060

taaagatgaa ttgatccatg agttaaagca gacactaaat gctatcaaat tagaagaaaa     3120

aggagtctat gtccaggcat ctacactggg ttctttggaa gctctactgg aatttctgaa     3180

aacatcagaa gtgccctatg caggaattaa cattggccca gtgcataaaa aagatgttat     3240

gaaggcttca gtgatgttgg aacatgaccc tcagtatgca gtaattttgg ccttcgatgt     3300

gagaattgaa cgagatgcac aagaaatggc tgatagttta ggagttagaa tttttagtgc     3360

agaaattatt tatcatttat ttgatgcctt tacaaaatat agacaagact acaagaaaca     3420

gaaacaagaa gaatttaagc acatagcagt atttccctgc aagataaaaa tcctccctca     3480

gtacattttt aattctcgag atccgatagt gatgggggtg acggtggaag caggtcaggt     3540

gaaacagggg acacccatgt gtgtcccaag caaaaatttt gttgacatcg gaatagtaac     3600

aagtattgaa ataaaccata aacaagtgga tgttgcaaaa aaaggacaag aagtttgtgt     3660

aaaaatagaa cctatccctg gtgagtcacc caaaatgttt ggaagacatt ttgaagctac     3720

agatattctt gttagtaaga tcagccggca gtccattgat gcactcaaag actggttcag     3780

agatgaaatg cagaagagtg actggcagct tattgtggag ctgaagaaag tatttgaaat     3840

catctaattt tttcacatgg agcaggaact ggagtaaatg caatactgtg ttgtaatatc     3900

ccaacaaaaa tcagacaaaa aatggaacag acgtatttgg acactgatgg acttaagtat     3960

ggaaggaaga aaaataggtg tataaaatgt tttccatgag aaaccaagaa acttacactg     4020

gtttgacagt ggtcagttac atgtccccac agttccaatg tgcctgttca ctcacctctc     4080

ccttccccaa cccttctcta cttggctgct gttttaaagt ttgcccttcc ccaaatttgg     4140

atttttatta cagatctaaa gctctttcga ttttatactg attaaatcag tactgcagta     4200

tttgattaac caagcttctg cagattttgt gattcttggg acttttttga cgtaagaaat     4260

acttctttat ttatgcatat tcttcccaca gtgatttttc cagcattctt ctgccatatg     4320

cctttagggc ttttataaaa tagaaaatta ggcattctga tatttcttta gctgctttgt     4380

gtgaaaccat ggtgtaaaag cacagctggc tgctttttac tgcttgtgta gtcacgagtc     4440

cattgtaatc atcacaattc taaaccaaac taccaataaa gaaaacagac atccaccagt     4500

aagcaagctc tgttaggctt ccatgttagt gtagcttctc tcccacaagt tgtcctccta     4560

ggacaagaat tatcttacaa actaaactat catcacacta ccttgtatgc cagcacctgg     4620

taacagtaga gatttttata cattaatctt gatctgtttt aatcttgatc tgttttagta     4680

gagattttta tacattaa                                                   4698


<210>  690
<211>  2200
<212>  DNA
<213>  homo sapiens

<400>  690
cttccgtcgg ccattttagg tggtccgcgg cggcgccatt aaagcgagga ggaggcgaga       60

gcggccgccg ctggtgctta ttctttttta gtgcagcggg agagagcggg agtgtgcgcc      120

gcgcgagagt gggaggcgaa gggggcaggc cagggagagg cgcaggagcc tttgcagcca      180

cgcgcgcgcc ttccctgtct tgtgtgcttc gcgaggtaga gcgggcgcgc ggcagcggcg      240

gggattactt tgctgctagt ttcggttcgc ggcagcggcg ggtgtagtct cggcggcagc      300

ggcggagaca ctagcactat gtcggaggag cagttcggcg gggacggggc ggcggcagcg      360

gcaacggcgg cggtaggcgg ctcggcgggc gagcaggagg gagccatggt ggcggcgaca      420

cagggggcag cggcggcggc gggaagcgga gccgggaccg ggggcggaac cgcgtctgga      480

ggcaccgaag ggggcagcgc cgagtcggag ggggcgaaga ttgacgccag taagaacgag      540

gaggatgaag ggaaaatgtt tataggaggc cttagctggg acactacaaa gaaagatctg      600

aaggactact tttccaaatt tggtgaagtt gtagactgca ctctgaagtt agatcctatc      660

acagggcgat caaggggttt tggctttgtg ctatttaaag aatcggagag tgtagataag      720

gtcatggatc aaaaagaaca taaattgaat gggaaggtga ttgatcctaa aagggccaaa      780

gccatgaaaa caaaagagcc ggttaaaaaa atttttgttg gtggcctttc tccagataca      840

cctgaagaga aaataaggga gtactttggt ggttttggtg aggtggaatc catagagctc      900

cccatggaca acaagaccaa taagaggcgt gggttctgct ttattacctt taaggaagaa      960

gaaccagtga agaagataat ggaaaagaaa taccacaatg ttggtcttag taaatgtgaa     1020

ataaaagtag ccatgtcgaa ggaacaatat cagcaacagc aacagtgggg atctagagga     1080

ggatttgcag gaagagctcg tggaagaggt ggtggcccca gtcaaaactg gaaccaggga     1140

tatagtaact attggaatca aggctatggc aactatggat ataacagcca aggttacggt     1200

ggttatggag gatatgacta cactggttac aacaactact atggatatgg tgattatagc     1260

aaccagcaga gtggttatgg gaaggtatcc aggcgaggtg gtcatcaaaa tagctacaaa     1320

ccatactaaa ttattccatt tgcaacttat ccccaacagg tggtgaagca gtattttcca     1380

atttgaagat tcatttgaag gtggctcctg ccacctgcta atagcagttc aaactaaatt     1440

ttttgtatca agtccctgaa tggaagtatg acgttgggtc cctctgaagt ttaattctga     1500

gttctcatta aaagaaattt gctttcattg ttttatttct taattgctat gcttcagaat     1560

caatttgtgt tttatgccct ttcccccagt attgtagagc aagtcttgtg ttaaaagccc     1620

agtgtgacag tgtcatgatg tagtagtgtc ttactggttt tttaataaat ccttttgtat     1680

aaaaatgtat tggctctttt atcatcagaa taggaaaaat tgtcatggat tcaagttatt     1740

aaaagcataa gtttggaaga caggcttgcc gaaattgagg acatgattaa aattgcagtg     1800

aagtttgaaa tgtttttagc aaaatctaat ttttgccata atgtgtcctc cctgtccaaa     1860

ttgggaatga cttaatgtca atttgtttgt tggttgtttt aataatactt ccttatgtag     1920

ccattaagat ttatatgaat attttcccaa atgcccagtt tttgcttaat atgtattgtg     1980

ctttttagaa caaatctgga taaatgtgca aaagtacccc tttgcacaga tagttaatgt     2040

tttatgcttc cattaaataa aaaggactta aaatctgtta attataatag aaatgcggct     2100

agttcagaga gatttttaga gctgtggtgg acttcataga tgaattcaag tgttgaggga     2160

ggattaaaga aatatatacc gtgtttatgt gtgtgtgctt                           2200


<210>  691
<211>  2110
<212>  DNA
<213>  homo sapiens

<400>  691
cttccgtcgg ccattttagg tggtccgcgg cggcgccatt aaagcgagga ggaggcgaga       60

gcggccgccg ctggtgctta ttctttttta gtgcagcggg agagagcggg agtgtgcgcc      120

gcgcgagagt gggaggcgaa gggggcaggc cagggagagg cgcaggagcc tttgcagcca      180

cgcgcgcgcc ttccctgtct tgtgtgcttc gcgaggtaga gcgggcgcgc ggcagcggcg      240

gggattactt tgctgctagt ttcggttcgc ggcagcggcg ggtgtagtct cggcggcagc      300

ggcggagaca ctagcactat gtcggaggag cagttcggcg gggacggggc ggcggcagcg      360

gcaacggcgg cggtaggcgg ctcggcgggc gagcaggagg gagccatggt ggcggcgaca      420

cagggggcag cggcggcggc gggaagcgga gccgggaccg ggggcggaac cgcgtctgga      480

ggcaccgaag ggggcagcgc cgagtcggag ggggcgaaga ttgacgccag taagaacgag      540

gaggatgaag gccattcaaa ctcctcccca cgacactctg aagcagcgac ggcacagcgg      600

gaagaatgga aaatgtttat aggaggcctt agctgggaca ctacaaagaa agatctgaag      660

gactactttt ccaaatttgg tgaagttgta gactgcactc tgaagttaga tcctatcaca      720

gggcgatcaa ggggttttgg ctttgtgcta tttaaagaat cggagagtgt agataaggtc      780

atggatcaaa aagaacataa attgaatggg aaggtgattg atcctaaaag ggccaaagcc      840

atgaaaacaa aagagccggt taaaaaaatt tttgttggtg gcctttctcc agatacacct      900

gaagagaaaa taagggagta ctttggtggt tttggtgagg tggaatccat agagctcccc      960

atggacaaca agaccaataa gaggcgtggg ttctgcttta ttacctttaa ggaagaagaa     1020

ccagtgaaga agataatgga aaagaaatac cacaatgttg gtcttagtaa atgtgaaata     1080

aaagtagcca tgtcgaagga acaatatcag caacagcaac agtggggatc tagaggagga     1140

tttgcaggaa gagctcgtgg aagaggtggt gaccagcaga gtggttatgg gaaggtatcc     1200

aggcgaggtg gtcatcaaaa tagctacaaa ccatactaaa ttattccatt tgcaacttat     1260

ccccaacagg tggtgaagca gtattttcca atttgaagat tcatttgaag gtggctcctg     1320

ccacctgcta atagcagttc aaactaaatt ttttgtatca agtccctgaa tggaagtatg     1380

acgttgggtc cctctgaagt ttaattctga gttctcatta aaagaaattt gctttcattg     1440

ttttatttct taattgctat gcttcagaat caatttgtgt tttatgccct ttcccccagt     1500

attgtagagc aagtcttgtg ttaaaagccc agtgtgacag tgtcatgatg tagtagtgtc     1560

ttactggttt tttaataaat ccttttgtat aaaaatgtat tggctctttt atcatcagaa     1620

taggaaaaat tgtcatggat tcaagttatt aaaagcataa gtttggaaga caggcttgcc     1680

gaaattgagg acatgattaa aattgcagtg aagtttgaaa tgtttttagc aaaatctaat     1740

ttttgccata atgtgtcctc cctgtccaaa ttgggaatga cttaatgtca atttgtttgt     1800

tggttgtttt aataatactt ccttatgtag ccattaagat ttatatgaat attttcccaa     1860

atgcccagtt tttgcttaat atgtattgtg ctttttagaa caaatctgga taaatgtgca     1920

aaagtacccc tttgcacaga tagttaatgt tttatgcttc cattaaataa aaaggactta     1980

aaatctgtta attataatag aaatgcggct agttcagaga gatttttaga gctgtggtgg     2040

acttcataga tgaattcaag tgttgaggga ggattaaaga aatatatacc gtgtttatgt     2100

gtgtgtgctt                                                            2110


<210>  692
<211>  2257
<212>  DNA
<213>  homo sapiens

<400>  692
cttccgtcgg ccattttagg tggtccgcgg cggcgccatt aaagcgagga ggaggcgaga       60

gcggccgccg ctggtgctta ttctttttta gtgcagcggg agagagcggg agtgtgcgcc      120

gcgcgagagt gggaggcgaa gggggcaggc cagggagagg cgcaggagcc tttgcagcca      180

cgcgcgcgcc ttccctgtct tgtgtgcttc gcgaggtaga gcgggcgcgc ggcagcggcg      240

gggattactt tgctgctagt ttcggttcgc ggcagcggcg ggtgtagtct cggcggcagc      300

ggcggagaca ctagcactat gtcggaggag cagttcggcg gggacggggc ggcggcagcg      360

gcaacggcgg cggtaggcgg ctcggcgggc gagcaggagg gagccatggt ggcggcgaca      420

cagggggcag cggcggcggc gggaagcgga gccgggaccg ggggcggaac cgcgtctgga      480

ggcaccgaag ggggcagcgc cgagtcggag ggggcgaaga ttgacgccag taagaacgag      540

gaggatgaag gccattcaaa ctcctcccca cgacactctg aagcagcgac ggcacagcgg      600

gaagaatgga aaatgtttat aggaggcctt agctgggaca ctacaaagaa agatctgaag      660

gactactttt ccaaatttgg tgaagttgta gactgcactc tgaagttaga tcctatcaca      720

gggcgatcaa ggggttttgg ctttgtgcta tttaaagaat cggagagtgt agataaggtc      780

atggatcaaa aagaacataa attgaatggg aaggtgattg atcctaaaag ggccaaagcc      840

atgaaaacaa aagagccggt taaaaaaatt tttgttggtg gcctttctcc agatacacct      900

gaagagaaaa taagggagta ctttggtggt tttggtgagg tggaatccat agagctcccc      960

atggacaaca agaccaataa gaggcgtggg ttctgcttta ttacctttaa ggaagaagaa     1020

ccagtgaaga agataatgga aaagaaatac cacaatgttg gtcttagtaa atgtgaaata     1080

aaagtagcca tgtcgaagga acaatatcag caacagcaac agtggggatc tagaggagga     1140

tttgcaggaa gagctcgtgg aagaggtggt ggccccagtc aaaactggaa ccagggatat     1200

agtaactatt ggaatcaagg ctatggcaac tatggatata acagccaagg ttacggtggt     1260

tatggaggat atgactacac tggttacaac aactactatg gatatggtga ttatagcaac     1320

cagcagagtg gttatgggaa ggtatccagg cgaggtggtc atcaaaatag ctacaaacca     1380

tactaaatta ttccatttgc aacttatccc caacaggtgg tgaagcagta ttttccaatt     1440

tgaagattca tttgaaggtg gctcctgcca cctgctaata gcagttcaaa ctaaattttt     1500

tgtatcaagt ccctgaatgg aagtatgacg ttgggtccct ctgaagttta attctgagtt     1560

ctcattaaaa gaaatttgct ttcattgttt tatttcttaa ttgctatgct tcagaatcaa     1620

tttgtgtttt atgccctttc ccccagtatt gtagagcaag tcttgtgtta aaagcccagt     1680

gtgacagtgt catgatgtag tagtgtctta ctggtttttt aataaatcct tttgtataaa     1740

aatgtattgg ctcttttatc atcagaatag gaaaaattgt catggattca agttattaaa     1800

agcataagtt tggaagacag gcttgccgaa attgaggaca tgattaaaat tgcagtgaag     1860

tttgaaatgt ttttagcaaa atctaatttt tgccataatg tgtcctccct gtccaaattg     1920

ggaatgactt aatgtcaatt tgtttgttgg ttgttttaat aatacttcct tatgtagcca     1980

ttaagattta tatgaatatt ttcccaaatg cccagttttt gcttaatatg tattgtgctt     2040

tttagaacaa atctggataa atgtgcaaaa gtaccccttt gcacagatag ttaatgtttt     2100

atgcttccat taaataaaaa ggacttaaaa tctgttaatt ataatagaaa tgcggctagt     2160

tcagagagat ttttagagct gtggtggact tcatagatga attcaagtgt tgagggagga     2220

ttaaagaaat atataccgtg tttatgtgtg tgtgctt                              2257


<210>  693
<211>  2200
<212>  DNA
<213>  homo sapiens

<400>  693
cttccgtcgg ccattttagg tggtccgcgg cggcgccatt aaagcgagga ggaggcgaga       60

gcggccgccg ctggtgctta ttctttttta gtgcagcggg agagagcggg agtgtgcgcc      120

gcgcgagagt gggaggcgaa gggggcaggc cagggagagg cgcaggagcc tttgcagcca      180

cgcgcgcgcc ttccctgtct tgtgtgcttc gcgaggtaga gcgggcgcgc ggcagcggcg      240

gggattactt tgctgctagt ttcggttcgc ggcagcggcg ggtgtagtct cggcggcagc      300

ggcggagaca ctagcactat gtcggaggag cagttcggcg gggacggggc ggcggcagcg      360

gcaacggcgg cggtaggcgg ctcggcgggc gagcaggagg gagccatggt ggcggcgaca      420

cagggggcag cggcggcggc gggaagcgga gccgggaccg ggggcggaac cgcgtctgga      480

ggcaccgaag ggggcagcgc cgagtcggag ggggcgaaga ttgacgccag taagaacgag      540

gaggatgaag ggaaaatgtt tataggaggc cttagctggg acactacaaa gaaagatctg      600

aaggactact tttccaaatt tggtgaagtt gtagactgca ctctgaagtt agatcctatc      660

acagggcgat caaggggttt tggctttgtg ctatttaaag aatcggagag tgtagataag      720

gtcatggatc aaaaagaaca taaattgaat gggaaggtga ttgatcctaa aagggccaaa      780

gccatgaaaa caaaagagcc ggttaaaaaa atttttgttg gtggcctttc tccagataca      840

cctgaagaga aaataaggga gtactttggt ggttttggtg aggtggaatc catagagctc      900

cccatggaca acaagaccaa taagaggcgt gggttctgct ttattacctt taaggaagaa      960

gaaccagtga agaagataat ggaaaagaaa taccacaatg ttggtcttag taaatgtgaa     1020

ataaaagtag ccatgtcgaa ggaacaatat cagcaacagc aacagtgggg atctagagga     1080

ggatttgcag gaagagctcg tggaagaggt ggtggcccca gtcaaaactg gaaccaggga     1140

tatagtaact attggaatca aggctatggc aactatggat ataacagcca aggttacggt     1200

ggttatggag gatatgacta cactggttac aacaactact atggatatgg tgattatagc     1260

aaccagcaga gtggttatgg gaaggtatcc aggcgaggtg gtcatcaaaa tagctacaaa     1320

ccatactaaa ttattccatt tgcaacttat ccccaacagg tggtgaagca gtattttcca     1380

atttgaagat tcatttgaag gtggctcctg ccacctgcta atagcagttc aaactaaatt     1440

ttttgtatca agtccctgaa tggaagtatg acgttgggtc cctctgaagt ttaattctga     1500

gttctcatta aaagaaattt gctttcattg ttttatttct taattgctat gcttcagaat     1560

caatttgtgt tttatgccct ttcccccagt attgtagagc aagtcttgtg ttaaaagccc     1620

agtgtgacag tgtcatgatg tagtagtgtc ttactggttt tttaataaat ccttttgtat     1680

aaaaatgtat tggctctttt atcatcagaa taggaaaaat tgtcatggat tcaagttatt     1740

aaaagcataa gtttggaaga caggcttgcc gaaattgagg acatgattaa aattgcagtg     1800

aagtttgaaa tgtttttagc aaaatctaat ttttgccata atgtgtcctc cctgtccaaa     1860

ttgggaatga cttaatgtca atttgtttgt tggttgtttt aataatactt ccttatgtag     1920

ccattaagat ttatatgaat attttcccaa atgcccagtt tttgcttaat atgtattgtg     1980

ctttttagaa caaatctgga taaatgtgca aaagtacccc tttgcacaga tagttaatgt     2040

tttatgcttc cattaaataa aaaggactta aaatctgtta attataatag aaatgcggct     2100

agttcagaga gatttttaga gctgtggtgg acttcataga tgaattcaag tgttgaggga     2160

ggattaaaga aatatatacc gtgtttatgt gtgtgtgctt                           2200


<210>  694
<211>  2257
<212>  DNA
<213>  homo sapiens

<400>  694
cttccgtcgg ccattttagg tggtccgcgg cggcgccatt aaagcgagga ggaggcgaga       60

gcggccgccg ctggtgctta ttctttttta gtgcagcggg agagagcggg agtgtgcgcc      120

gcgcgagagt gggaggcgaa gggggcaggc cagggagagg cgcaggagcc tttgcagcca      180

cgcgcgcgcc ttccctgtct tgtgtgcttc gcgaggtaga gcgggcgcgc ggcagcggcg      240

gggattactt tgctgctagt ttcggttcgc ggcagcggcg ggtgtagtct cggcggcagc      300

ggcggagaca ctagcactat gtcggaggag cagttcggcg gggacggggc ggcggcagcg      360

gcaacggcgg cggtaggcgg ctcggcgggc gagcaggagg gagccatggt ggcggcgaca      420

cagggggcag cggcggcggc gggaagcgga gccgggaccg ggggcggaac cgcgtctgga      480

ggcaccgaag ggggcagcgc cgagtcggag ggggcgaaga ttgacgccag taagaacgag      540

gaggatgaag gccattcaaa ctcctcccca cgacactctg aagcagcgac ggcacagcgg      600

gaagaatgga aaatgtttat aggaggcctt agctgggaca ctacaaagaa agatctgaag      660

gactactttt ccaaatttgg tgaagttgta gactgcactc tgaagttaga tcctatcaca      720

gggcgatcaa ggggttttgg ctttgtgcta tttaaagaat cggagagtgt agataaggtc      780

atggatcaaa aagaacataa attgaatggg aaggtgattg atcctaaaag ggccaaagcc      840

atgaaaacaa aagagccggt taaaaaaatt tttgttggtg gcctttctcc agatacacct      900

gaagagaaaa taagggagta ctttggtggt tttggtgagg tggaatccat agagctcccc      960

atggacaaca agaccaataa gaggcgtggg ttctgcttta ttacctttaa ggaagaagaa     1020

ccagtgaaga agataatgga aaagaaatac cacaatgttg gtcttagtaa atgtgaaata     1080

aaagtagcca tgtcgaagga acaatatcag caacagcaac agtggggatc tagaggagga     1140

tttgcaggaa gagctcgtgg aagaggtggt ggccccagtc aaaactggaa ccagggatat     1200

agtaactatt ggaatcaagg ctatggcaac tatggatata acagccaagg ttacggtggt     1260

tatggaggat atgactacac tggttacaac aactactatg gatatggtga ttatagcaac     1320

cagcagagtg gttatgggaa ggtatccagg cgaggtggtc atcaaaatag ctacaaacca     1380

tactaaatta ttccatttgc aacttatccc caacaggtgg tgaagcagta ttttccaatt     1440

tgaagattca tttgaaggtg gctcctgcca cctgctaata gcagttcaaa ctaaattttt     1500

tgtatcaagt ccctgaatgg aagtatgacg ttgggtccct ctgaagttta attctgagtt     1560

ctcattaaaa gaaatttgct ttcattgttt tatttcttaa ttgctatgct tcagaatcaa     1620

tttgtgtttt atgccctttc ccccagtatt gtagagcaag tcttgtgtta aaagcccagt     1680

gtgacagtgt catgatgtag tagtgtctta ctggtttttt aataaatcct tttgtataaa     1740

aatgtattgg ctcttttatc atcagaatag gaaaaattgt catggattca agttattaaa     1800

agcataagtt tggaagacag gcttgccgaa attgaggaca tgattaaaat tgcagtgaag     1860

tttgaaatgt ttttagcaaa atctaatttt tgccataatg tgtcctccct gtccaaattg     1920

ggaatgactt aatgtcaatt tgtttgttgg ttgttttaat aatacttcct tatgtagcca     1980

ttaagattta tatgaatatt ttcccaaatg cccagttttt gcttaatatg tattgtgctt     2040

tttagaacaa atctggataa atgtgcaaaa gtaccccttt gcacagatag ttaatgtttt     2100

atgcttccat taaataaaaa ggacttaaaa tctgttaatt ataatagaaa tgcggctagt     2160

tcagagagat ttttagagct gtggtggact tcatagatga attcaagtgt tgagggagga     2220

ttaaagaaat atataccgtg tttatgtgtg tgtgctt                              2257


<210>  695
<211>  2274
<212>  DNA
<213>  homo sapiens

<400>  695
gcagaactcg cacaagggac cttatttagg ttgcgcaggc gcccgctggc catttcgtct       60

tagccacgca gaagtcgcgt gtctagtttg tttcgacgcc ggaccgcgta agagacgatg      120

atgttgggca cggaaggtgg agagggattc gtggtgaagg tccggggctt gccctggtct      180

tgctcggccg atgaagtgca gaggtttttt tctgactgca aaattcaaaa tggggctcaa      240

ggtattcgtt tcatctacac cagagaaggc agaccaagtg gcgaggcttt tgttgaactt      300

gaatcagaag atgaagtcaa attggccctg aaaaaagaca gagaaactat gggacacaga      360

tatgttgaag tattcaagtc aaacaacgtt gaaatggatt gggtgttgaa gcatactggt      420

ccaaatagtc ctgacacggc caatgatggc tttgtacggc ttagaggact tccctttgga      480

tgtagcaagg aagaaattgt tcagttcttc tcagggttgg aaatcgtgcc aaatgggata      540

acattgccgg tggacttcca ggggaggagt acgggggagg ccttcgtgca gtttgcttca      600

caggaaatag ctgaaaaggc tctaaagaaa cacaaggaaa gaatagggca caggtatatt      660

gaaatcttta agagcagtag agctgaagtt agaactcatt atgatccacc acgaaagctt      720

atggccatgc agcggccagg tccttatgac agacctgggg ctggtagagg gtataacagc      780

attggcagag gagctggctt tgagaggatg aggcgtggtg cttatggtgg aggctatgga      840

ggctatgatg attacaatgg ctataatgat ggctatggat ttgggtcaga tagatttgga      900

agagacctca attactgttt ttcaggaatg tctgatcaca gatacgggga tggtggctct      960

actttccaga gcacaacagg acactgtgta cacatgcggg gattacctta cagagctact     1020

gagaatgaca tttataattt tttttcaccg ctcaaccctg tgagagtaca cattgaaatt     1080

ggtcctgatg gcagagtaac tggtgaagca gatgtcgagt tcgcaactca tgaagatgct     1140

gtggcagcta tgtcaaaaga caaagcaaat atgcaacaca gatatgtaga actcttcttg     1200

aattctacag caggagcaag cggtggtgct tacgaacaca gatatgtaga actcttcttg     1260

aattctacag caggagcaag cggtggtgct tatggtagcc aaatgatggg aggcatgggc     1320

ttgtcaaacc agtccagcta cgggggccca gccagccagc agctgagtgg gggttacgga     1380

ggcggctacg gtggccagag cagcatgagt ggatacgacc aagttttaca ggaaaactcc     1440

agtgattttc aatcaaacat tgcataggta accaaggagc agtgaacagc agctactaca     1500

gtagtggaag ccgtgcatct atgggcgtga acggaatggg agggttgtct agcatgtcca     1560

gtatgagtgg tggatgggga atgtaattga tcgatcctga tcactgactc ttggtcaacc     1620

tttttttttt tttttttttt ttctttaaga aaacttcagt ttaacagttt ctgcaataca     1680

agcttgtgat ttatgcttac tctaagtgga aatcaggatt gttatgaaga cttaaggccc     1740

agtatttttg aatacaatac tcatctagga tgtaacagtg aagctgagta aactataact     1800

gttaaactta agttccagct tttctcaagt tagttatagg atgtacttaa gcagtaagcg     1860

tatttaggta aaagcagttg aattatgtta aatgttgccc tttgccacgt taaattgaac     1920

actgttttgg atgcatgttg aaagacatgc ttttattttt ttgtaaaaca atataggagc     1980

tgtgtctact attaaaagtg aaacattttg gcatgtttgt taattctagt ttcatttaat     2040

aacctgtaag gcacgtaagt ttaagctttt ttttttttta agttaatggg aaaaatttga     2100

gacgcaatac caatacttag gattttggtc ttggtgtttg tatgaaattc tgaggccttg     2160

atttaaatct ttcattgtat tgtgatttcc ttttaggtat attgcgctaa gtgaaacttg     2220

tcaaataaat cctcctttta aaaactgcaa aaaaaaaaaa aaaaaaaaaa aaaa           2274


<210>  696
<211>  2780
<212>  DNA
<213>  homo sapiens

<400>  696
gaacgcaagt cccgcttcgc tctcgggggc ggactcagcg gcggaagtgg cgctgccgga       60

agatcttctt ccgctctgag gcgctactga ggccgcggag ccggactgcg gttggggcgg      120

gaagagccgg ggccgtggct gacatggagc agccctgctg ctgaggccgc gccctccccg      180

ccctgaggtg ggggcccacc aggatgagca agctgcccag ggagctgacc cgagacttgg      240

agcgcagcct gcctgccgtg gcctccctgg gctcctcact gtcccacagc cagagcctct      300

cctcgcacct ccttccgccg cctgagaagc gaagggccat ctctgatgtc cgccgcacct      360

tctgtctctt cgtcaccttc gacctgctct tcatctccct gctctggatc atcgaactga      420

ataccaacac aggcatccgt aagaacttgg agcaggagat catccagtac aactttaaaa      480

cttccttctt cgacatcttt gtcctggcct tcttccgctt ctctggactg ctcctaggct      540

atgccgtgct gcggctccgg cactggtggg tgattgcgct gctcagcaaa ggggcatttg      600

gctacctgct ccccatcgtc tcttttgtcc tcgcctggtt ggagacctgg ttccttgact      660

tcaaagtcct accccaggaa gctgaagagg agcgatggta tcttgccgcc caggttgctg      720

ttgcccgtgg acccctgctg ttctccggtg ctctgtccga gggacagttc tattcacccc      780

cagaatcctt tgcagggtct gacaatgaat cagatgaaga agttgctggg aagaaaagtt      840

tctctgctca ggagcgggag tacatccgcc aggggaagga ggccacggca gtggtggacc      900

agatcttggc ccaggaagag aactggaagt ttgagaagaa taatgaatat ggggacaccg      960

tgtacaccat tgaagttccc tttcacggca agacgtttat cctgaagacc ttcctgccct     1020

gtcctgcgga gctcgtgtac caggaggtga tcctgcagcc cgagaggatg gtgctgtgga     1080

acaagacagt gactgcctgc cagatcctgc agcgagtgga agacaacacc ctcatctcct     1140

atgacgtgtc tgcaggggct gcgggcggcg tggtctcccc aagggacttc gtgaatgtcc     1200

ggcgcattga gcggcgcagg gaccgatact tgtcatcagg gatcgccacc tcacacagtg     1260

ccaagccccc gacgcacaaa tatgtccggg gagagaatgg ccctgggggc ttcatcgtgc     1320

tcaagtcggc cagtaacccc cgtgtttgca cctttgtctg gattcttaat acagatctca     1380

agggccgcct gccccggtac ctcatccacc agagcctcgc ggccaccatg tttgaatttg     1440

cctttcacct gcgacagcgc atcagcgagc tgggggcccg ggcgtgactg tgccccctcc     1500

caccctgcgg gccagggtcc tgtcgccacc acttccagag ccagaaaggg tgccagttgg     1560

gctcgcactg cccacatggg acctggcccc aggctgtcac cctccaccga gccacgcagt     1620

gcctggagtt gactgactga gcaggctgtg gggtggagca ctggactccg gggccccact     1680

ggctggagga agtggggtct ggcctgttga tgtttacatg gcgccctgcc tcctggagga     1740

ccagattgct ctgccccacc ttgccagggc agggtctggg ctgggcacct gacttggctg     1800

gggaggacca gggccctggg cagggcaggg cagcctgtca cccgtgtgaa gatgaagggg     1860

ctcttcatct gcctgcgctc tcgtcggttt ttttaggatt attgaaagag tctgggaccc     1920

ttgttgggga gtgggtggca ggtgggggtg ggctgctggc catgaatctc tgcctctccc     1980

aggctgtccc cctcctccca gggcctcctg ggggaccttt gtattaagcc aattaaaaac     2040

atgaatttaa aaaaaaaaaa aaattccagc ccctcccact gccttgcctc ttgagggaag     2100

agaaaggcag gcagcagctt ggatgaagag ggaagacccc tcacacagcc tctcctgggc     2160

tcacaggagg gcggagcccg gggagccagt tcctgaaaca tgccccccat tccccccccg     2220

cccacccccc actccccgct ttcctgacca gttcaactga gcagatgact ggtcagaaaa     2280

aaatgccccg ccccctgcca ggcttcagcg gggcaagttt aaagtctcta gtccaggaat     2340

ggaggtgggg gtatgggcac ctggcagtgc ccacagcaag ccttgactgt gtggcctgga     2400

gatggggcct gagcttcagg gtcactgagg cacctctggg atccaggcca cctggagccc     2460

cggacctccc agactccact cacccattcc ctctccccgc acggcactca caccaggggc     2520

ggcctggagc ccggatcgca gggcggggcc aggccactgc ctgccttcct cctccctccc     2580

ggctggcctg cccccttgcc tgcctgcatg caggcttcca gcagagccag cttcttcaga     2640

gccaggtgga tcctgtttcg gtcctgccta ggtgtgtgac cctgggcgaa tctacctctc     2700

tcagcttctg cttcccactt tatgaaaatg ggactgatgt cacagggttg ttatgagatt     2760

aaaagatatg aagaaccggg                                                 2780


<210>  697
<211>  2834
<212>  DNA
<213>  homo sapiens

<400>  697
gaacgcaagt cccgcttcgc tctcgggggc ggactcagcg gcggaagtgg cgctgccgga       60

agatcttctt ccgctctgag gcgctactga ggccgcggag ccggactgcg gttggggcgg      120

gaagagccgg ggccgtggct gacatggagc agccctgctg ctgaggccgc gccctccccg      180

ccctgaggtg ggggcccacc aggatgagca agctgcccag ggagctgacc cgagacttgg      240

agcgcagcct gcctgccgtg gcctccctgg gctcctcact gtcccacagc cagagcctct      300

cctcgcacct ccttccgccg cctgagaagc gaagggccat ctctgatgtc cgccgcacct      360

tctgtctctt cgtcaccttc gacctgctct tcatctccct gctctggatc atcgaactga      420

ataccaacac aggcatccgt aagaacttgg agcaggagat catccagtac aactttaaaa      480

cttccttctt cgacatcttt gtcctggcct tcttccgctt ctctggactg ctcctaggct      540

atgccgtgct gcggctccgg cactggtggg tgattgcggt cacgacgctg gtgtccagtg      600

cattcctcat tgtcaaggtc atcctctctg agctgctcag caaaggggca tttggctacc      660

tgctccccat cgtctctttt gtcctcgcct ggttggagac ctggttcctt gacttcaaag      720

tcctacccca ggaagctgaa gaggagcgat ggtatcttgc cgcccaggtt gctgttgccc      780

gtggacccct gctgttctcc ggtgctctgt ccgagggaca gttctattca cccccagaat      840

cctttgcagg gtctgacaat gaatcagatg aagaagttgc tgggaagaaa agtttctctg      900

ctcaggagcg ggagtacatc cgccagggga aggaggccac ggcagtggtg gaccagatct      960

tggcccagga agagaactgg aagtttgaga agaataatga atatggggac accgtgtaca     1020

ccattgaagt tccctttcac ggcaagacgt ttatcctgaa gaccttcctg ccctgtcctg     1080

cggagctcgt gtaccaggag gtgatcctgc agcccgagag gatggtgctg tggaacaaga     1140

cagtgactgc ctgccagatc ctgcagcgag tggaagacaa caccctcatc tcctatgacg     1200

tgtctgcagg ggctgcgggc ggcgtggtct ccccaaggga cttcgtgaat gtccggcgca     1260

ttgagcggcg cagggaccga tacttgtcat cagggatcgc cacctcacac agtgccaagc     1320

ccccgacgca caaatatgtc cggggagaga atggccctgg gggcttcatc gtgctcaagt     1380

cggccagtaa cccccgtgtt tgcacctttg tctggattct taatacagat ctcaagggcc     1440

gcctgccccg gtacctcatc caccagagcc tcgcggccac catgtttgaa tttgcctttc     1500

acctgcgaca gcgcatcagc gagctggggg cccgggcgtg actgtgcccc ctcccaccct     1560

gcgggccagg gtcctgtcgc caccacttcc agagccagaa agggtgccag ttgggctcgc     1620

actgcccaca tgggacctgg ccccaggctg tcaccctcca ccgagccacg cagtgcctgg     1680

agttgactga ctgagcaggc tgtggggtgg agcactggac tccggggccc cactggctgg     1740

aggaagtggg gtctggcctg ttgatgttta catggcgccc tgcctcctgg aggaccagat     1800

tgctctgccc caccttgcca gggcagggtc tgggctgggc acctgacttg gctggggagg     1860

accagggccc tgggcagggc agggcagcct gtcacccgtg tgaagatgaa ggggctcttc     1920

atctgcctgc gctctcgtcg gtttttttag gattattgaa agagtctggg acccttgttg     1980

gggagtgggt ggcaggtggg ggtgggctgc tggccatgaa tctctgcctc tcccaggctg     2040

tccccctcct cccagggcct cctgggggac ctttgtatta agccaattaa aaacatgaat     2100

ttaaaaaaaa aaaaaaattc cagcccctcc cactgccttg cctcttgagg gaagagaaag     2160

gcaggcagca gcttggatga agagggaaga cccctcacac agcctctcct gggctcacag     2220

gagggcggag cccggggagc cagttcctga aacatgcccc ccattccccc cccgcccacc     2280

ccccactccc cgctttcctg accagttcaa ctgagcagat gactggtcag aaaaaaatgc     2340

cccgccccct gccaggcttc agcggggcaa gtttaaagtc tctagtccag gaatggaggt     2400

gggggtatgg gcacctggca gtgcccacag caagccttga ctgtgtggcc tggagatggg     2460

gcctgagctt cagggtcact gaggcacctc tgggatccag gccacctgga gccccggacc     2520

tcccagactc cactcaccca ttccctctcc ccgcacggca ctcacaccag gggcggcctg     2580

gagcccggat cgcagggcgg ggccaggcca ctgcctgcct tcctcctccc tcccggctgg     2640

cctgccccct tgcctgcctg catgcaggct tccagcagag ccagcttctt cagagccagg     2700

tggatcctgt ttcggtcctg cctaggtgtg tgaccctggg cgaatctacc tctctcagct     2760

tctgcttccc actttatgaa aatgggactg atgtcacagg gttgttatga gattaaaaga     2820

tatgaagaac cggg                                                       2834


<210>  698
<211>  2501
<212>  DNA
<213>  homo sapiens

<400>  698
gcacttccca gtttctgctc agccgtatta aggaaaagaa aggcatacga taggagcgga       60

atcttatctt aaccatcttt cttattgatt attccgctat tagaaagtgg aggaatcagc      120

cctttgatgt gattgtgttt atctctgcat ctcttttgtt atttttagag acctagaaga      180

ggaaaaaagg cacgagactt ttcaacacat cgtttaaaaa aatcatcaac gaatttcttg      240

caatgtttga gaacaattaa aaggaaaaag cgttttttaa aaaatctatc aactaagtga      300

acaatcattc atatcgtcta catcctgaga tattattgtc cctcgctgcg gacaccagcg      360

agatgacagc tgctttttca tttttgaatg taataaatat ttgctgcttt taatattttc      420

cggaatctcc cctcgctatt ccttggaatt ttaactctaa agattggaga acagattatc      480

aaaaaggctt ttgcaagcct ccaaaatgat gctgagtccg gaccaagcag cagattcgga      540

ccatcccagc tcggcgcact cggatccgga gtccctgggc ggcacggaca ccaaggtgct      600

cggcagcgtg tcggacctgg agccggtgga ggaggccgag ggcgacggca agggcggcag      660

ccgagccgcg ctctacccgc acccgcagca gctgagccgc gaggagaagc gccgccgccg      720

gcgcgccacg gccaagtacc gctcggccca cgccacccgc gagcgcatcc gcgtggaagc      780

cttcaacttg gccttcgccg agctccgcaa attgctgccc acgctgcccc cggacaagaa      840

gctctccaag atcgagatcc tgcgcctggc catctgctac atctcctatc tcaaccacgt      900

cctggacgtg tagggcgggg tgcgccgcgg ggggccgcct gtcccggcgt ccgcgaaacg      960

ctacggatcc ggacgggcgc cgtcgctcgg gtggcggagg ctgcggtggc ccagcgagac     1020

ggccgcctcg agagacggcc ggggaagaag ctcgctacct gttctctctg gtcagcaggg     1080

cgacgaggga aggtttccga cgcaggcagg tggggttgtc tggcgagccc gggggctcgc     1140

aggggggatt ttccaggcca ggagaacctc gtggagacac ccgagatgag ccacttctgg     1200

ggctccccaa gggttgtggt tttaacccac tggagacttt gagttctcct acattcatcc     1260

gccacaaatc ttaatgtgtt gaaagaatga gggcagaagt tcagagtatg caggctcata     1320

actttaggct atctggaatt tttctaatgg acaaatcacc aaacactggg aaggaggaga     1380

gaggagggat ctctcccata gagatggaag gcacagaaag gtgcgactgg aaactttcct     1440

ttctgttgtg aaaataaaga ttatattaga atccaaataa accctgaata tttagtaagt     1500

ttaaaaagac aaattgagaa caagtagaca cactgtggga ggatctgagc ttggtgatat     1560

tttatcccca agatatgaca ccaaggtaga caggaaaatc catatttaaa tggaaacttt     1620

aatatctgat tacttttgca ggcgaagtgc ccctttatat atccaaaaac atctatttgt     1680

gaccttaaac atgtggaccc ataggtgcag ttagaaaaag acaacctatt tttatttatg     1740

ttagaaggag tagagtattt ttttcaagac atttattttt cagagtggtg atacttttac     1800

tttggatact ctgtgccaat ttatttatag tcaagtgttt acactttttc ctgtggaata     1860

attatgtcta actttttacg tgtttgttga gattatactg tggtctttct ttctgctcta     1920

attatattgc acttgtataa caaatttccc acttctccct gtttctaaac atattttata     1980

tattaagatg tttgttcttg aaaggttctt ttgttgtgag atcagcaaca ctagcacttc     2040

actattatag ttttttaaaa agtgtattat tcttatctgt agttatgtct gagaagtcct     2100

ttacaagctg tttataagga gagtagcttc tttgtgtgtg tgatgtttgt gcgtgtgatg     2160

aatttagcaa attaagttat tttcctaaaa aaaaaagaaa aaaagaattc agaactactt     2220

tcctctgtga caccaaaaag aaaagtctat aacctgaaaa tgtttcatgt tctctgctgt     2280

gaaactctta aaacaaggag tgtattttag agacaaggga aaaaaaccac atctgctatc     2340

caaagatttt agtctttttc agggtttttt tgtgtctctg ttgctttata taatgcaata     2400

ttttgtagtg aaaatagata taatctggtt tctatctgac gagtttttca tatctcatga     2460

atggtgcgct gttttgcata taaataaagg tatcaaataa a                         2501


<210>  699
<211>  4580
<212>  DNA
<213>  homo sapiens

<400>  699
gtagttttct ggacccacgg gacgggcagg agctggagct ccgtgccgcc tgtactcccg       60

ccttcatttc ccatcgtgct gaggcgggtg gcatggcgga gaaggatgac accggagttt      120

gacgaagagg tggtttttga gaattctcca ctttaccaat acttacagga tctgggacac      180

acagactttg aaatatgttc ttctttgtca ccaaaaacag aaaaatgcac aacagaggga      240

caacaaaagc ctcctacaag agtcctacca aaacaaggta tcctgttaaa agtggctgaa      300

accatcaaaa gttggatttt tttttctcag tgcaataaga aagatgactt acttcacaag      360

ttggatattg gattccgact cgactcatta cataccatcc tgcaacagga agtcctgtta      420

caagaggatg tggagctgat tgagctactt gatcccagta tcctgtctgc agggcaatct      480

caacaacagg aaaatggaca ccttccaaca ctttgctccc tggcaacccc taatatttgg      540

gatctctcaa tgctatttgc cttcattagc ttgctcgtta tgcttcccac ttggtggatt      600

gtgtcttcct ggctggtatg gggagtgatt ctatttgtgt atctggtcat aagagctttg      660

agattatgga ggacagccaa actacaagtg accctaaaaa aatacagcgt tcatttggaa      720

gatatggcca caaacagccg agcttttact aacctcgtga gaaaagcttt acgtctcatt      780

caagaaaccg aagtgatttc cagaggattt acactggtca gtgctgcttg cccatttaat      840

aaagctggac agcatccaag tcagcatctc atcggtcttc ggaaagctgt ctaccgaact      900

ctaagagcca acttccaagc agcaaggcta gctaccctat atatgctgaa aaactacccc      960

ctgaactctg agagtgacaa tgtaaccaac tacatctgtg tggtgccttt taaagagctg     1020

ggccttggac ttagtgaaga gcagatttca gaagaggaag cacataactt tacagatggc     1080

ttcagcctgc ctgcattgaa ggttttgttc caactctggg tggcacagag ttcagagttc     1140

ttcagacggt tagccctatt actttctaca gccaattcac ctcctgggcc cttacttact     1200

ccagcacttc tgcctcatcg tatcttatct gatgtgactc aaggtctacc tcatgctcat     1260

tctgcctgtt tggaagagct taagcgcagc tatgagttct atcggtactt tgaaactcag     1320

caccagtcag taccgcagtg tttatccaaa actcaacaga agtcaagaga actgaataat     1380

gttcacacag cagtgcgtag cttgcagctc catctgaaag cattactgaa tgaggtaata     1440

attcttgaag atgaacttga aaagcttgtt tgtactaaag aaacacaaga actagtgtca     1500

gaggcttatc ccatcctaga acagaaatta aagttgattc agccccacgt tcaagcaagc     1560

aacaattgct gggaagaggc catttctcag gtcgacaaac tgctacgaag aaatacagat     1620

aaaaaaggca agcctgaaat agcatgtgaa aacccacatt gtacagtagt acctttgaag     1680

cagcctactc tacacattgc agacaaagat ccaatcccag aggagcagga attagaagct     1740

tatgtagatg atatagatat tgatagtgat ttcagaaagg atgattttta ttacttgtct     1800

caagaagaca aagagagaca gaagcgtgag catgaagaat ccaagagggt gctccaagaa     1860

ttaaaatctg tgctgggatt taaagcttca gaggcagaaa ggcagaagtg gaagcaactt     1920

ctatttagtg atcatgccgt gttgaaatcc ttgtctcctg tagacccagt ggaacccata     1980

agtaattcag aaccatcaat gaattcagat atgggaaaag tcagtaaaaa tgatactgaa     2040

gaggaaagta ataaatccgc cacaacagac aatgaaataa gtaggactga gtatttatgt     2100

gaaaactctc tagaaggtaa aaataaagat aattcttcaa atgaagtctt cccccaagga     2160

gcagaagaaa gaatgtgtta ccaatgtgag agtgaagatg aaccacaagc agatggaagt     2220

ggtctgacca ctgcccctcc aactcccagg gactcattac agccctccat taagcagagg     2280

ctggcacggc tacagctgtc accagatttt accttcactg ctggccttgc tgcagaagtg     2340

gctgctagat ctctctcctt taccaccatg caggaacaga cttttggtgg tgaggaggaa     2400

gaacaaataa tagaagaaaa taaaaatgag atagaagaaa agtaagaacc aagattcata     2460

tgaagtgata ttagattgtt ccttttacaa aagtgtttag cttcaagact ggaaagggaa     2520

tatgagtgta agtttactat atataaagct aagatgtgga tttacaggaa gaaccctggt     2580

ttgaataact gatctgaaat tagtagttac ctgtaaatgg cagatctttt aggaaaataa     2640

gagaaaggta agggctcttt tgaataaact gctgttttat ttgtggcaca actgatcaat     2700

cttggaaatt ctttaagtat ttttaataag aaatgaatta tcatttcttg ccagaatttg     2760

ctaccttaag gtgattggga aaattctgtt gcaagaacat taacatttag tatgactcct     2820

ttttactgta ttcttgcagt taataactgc agctattatg ttaataacaa gttgtttgta     2880

ttttattttt gtttatacca gtcttaaaga tccaggttct gaataaaaaa attaattgat     2940

acaattgatg tgtgctgggg tttggaacta aaagtagttt caacagtgcg tgggttatga     3000

catttcttat gtttctttgt tcatgtgtgt atttagtagt taattttaag atgtcctagt     3060

gatctttaaa agaaaaatat tgtaccattt tttagaatta cactttcacc tttctttttg     3120

caattgaaag tgatgatgtc aaagtgggat ttctgtactc caaggcccca cccccaattt     3180

agcaagcaga aaaacgttcc ttgtatcact ttaccttgga taattgggtg ccattaacac     3240

aaacaggtca caatcctgct gttttctagc cctgtccacc ataatgagat tcaggaaaca     3300

tcctgtcagc ctcctggaaa gcatccttgt ctccttagta tttcatttac aaactacctc     3360

ttaacagaga ctgcttttca aattggccaa tcttacctgt tttgtgttgt gattgcattt     3420

tcaaagagta attattttca gcatatacag ttttgaaacc tgtagctcct atgcaataac     3480

atagttctat agacattatt tgggggaaat gtagtaataa ctcaatctat gttgctgtcc     3540

tagaaaggaa attgcatgat gaatctagat tgtctttaga gtaaagaaac acattcaaat     3600

tcctgtaact tatcactttc agtgagtaaa tttacttata ccaaagggga ttttttttct     3660

ttcaggaatc taaggaaatt tactttttaa cctgagaaaa aaacttggtt ctgctttata     3720

taaacagtag agattattgt actataagtg attttgcctt tttgccaaaa tcctggaact     3780

catctataat taacctcttc ggagcaatac cttaggttgg gccttgcttt actacttaga     3840

aatagctaaa tttcaatttt aaaaatcttt gtgtgttata actgttaaat tattcaataa     3900

tacttagggt ttactttctt atttaaatca cttatttagt ttaccgactt catttttctt     3960

tggatttaga agaagcaatt atggaaaaac ttggtaatct ctctcaacct ataaccttac     4020

acaggaagaa ttagagttta ataattttta attcttttat tgtatgttac ttttattaca     4080

ccagtttggg ggaaaatctt cataaaattg tatcagtttt attcagtgtt ctctaaggtg     4140

atacctttta attttgaaag actaaataat tttaatcgag aatttccagt ctttcagtct     4200

gatctattta attcactact tgttacataa tccagtgaaa actctacttg ttgaaattat     4260

gacataaaga tcttgcagct ttatttgagt atttgttctt ttgtgtagtt tccatctttt     4320

aaaatattta aaatattttc aagataaagt attatcttct ctgcaaaaat tcctggagta     4380

attttctctc ataatatttg aagtcagtgg ttctcagttg tattagtggg gtaactacat     4440

caaaataaat aaagtcttat ttttaaaatg caaattttag accatactcc cagtgattct     4500

tagttggtct ttttggaatg agccataggt aatgtttatg tccaataaaa tctaggaacc     4560

tcaaaaaaaa aaaaaaaaaa                                                 4580


<210>  700
<211>  3296
<212>  DNA
<213>  homo sapiens

<400>  700
taagaaacga cacacagatt aggcagtgct actcttctta aatctctcat ttgtttccta       60

ggttccctgg ttgtgaaaat acatgagata aatcatgaag gccactatca tcctccttct      120

gcttgcacaa gtttcctggg ctggaccgtt tcaacagaga ggcttatttg actttatgct      180

agaagatgag gcttctggga taggcccaga agttcctgat gaccgcgact tcgagccctc      240

cctaggccca gtgtgcccct tccgctgtca atgccatctt cgagtggtcc agtgttctga      300

tttgggttgt ctaccttcat aacaacaata tctctgtagt tggatcaagt gacttctgcc      360

cacctggaca caacaccaaa aaggcttctt attcgggtgt gagtcttttc agcaacccgg      420

tccagtactg ggagatacag ccatccacct tcagatgtgt ctacgtgcgc tctgccattc      480

aactcggaaa ctataagtaa ttctcaagaa agccctcatt tttataacct ggcaaaatct      540

tgttaatgtc attgctaaaa aataaataaa agctagatac tggaaaccta actgcaatgt      600

ggatgtttta cccacatgac ttattatgca taaagccaaa tttccagttt aagtaattgc      660

ctacaataaa aagaaatttt gcctgccatt ttcagaatca tcttttgaag ctttctgttg      720

atgttaactg agctactaga gatattctta tttcactaaa tgtaaaattt ggagtaaata      780

tatatgtcaa tatttagtaa agcttttctt ttttaatttc caggaaaaaa taaaaagagt      840

atgagtcttc tgtaattcat tgagcagtta gctcatttga gataaagtca aatgccaaac      900

actagctctg tattaatccc catcattact ggtaaagcct catttgaatg tgtgaattca      960

atacaggcta tgtaaaattt ttactaatgt cattattttg aaaaaataaa tttaaaaata     1020

cattcaaaat tactattgta tacaagctta attgttaata ttccctaaac acaattttat     1080

gaagggagaa gacattggtt tgttgacaat aacagtacat cttttcaagt tctcagctat     1140

ttcttctacc tctccctatc ttacatttga gtatggtaac ttatgtcatc tatgttgaat     1200

gtaagcttat aaagcacaaa gcatacattt cctgactggt ctagagaact gatgtttcaa     1260

tttacccctc tgctaaataa atattaaaac tatcatgtga cttcatgtaa tcaggctgaa     1320

catttctaca attactagat gtattagacg taagtatttt ctttagttaa accacccatg     1380

ttagaaatgt tttctgtaga atttataaac aactatcaat gcagacaatt taataagcct     1440

ggggatgatt tacttacagt aaacatttat caaattgtac atttgtgcta tcaacaatta     1500

ataagcaaat atgtgaaaat agtttctgtc ttctatgaag ttagatattt gatggttaaa     1560

acccctataa atcatagttt catatgggaa aaaataattg aaatacagtg taaatttaaa     1620

taatttatta agtatagcaa ataattgaaa tatggtggac taaattttgt catagaaata     1680

tgtgcaagtt atagtagtgg ctcacatgag aggtaatcaa ttctgctaat agtagcagaa     1740

tgagtgcagt ggaacatgaa aaacttgagg agataacagt tgaggtgggt ttccatagat     1800

gcataatagt tcaagagcaa gatttggtgg ggaggcacta ttcaagacag ggactaagtt     1860

caaaatccaa gacgtatgct gggacacacc tctgacaggt tggcataaag gaggcttaat     1920

caaactattt ttcttcttct gaaacagaag caataatttt catttacatt tgacatatcc     1980

cgaggtaata ttaacattag ggaaagttac tcttttccat ctttccacat tcttgcagga     2040

ccataaaatc tgaattttcc agtattttta ataagaggga agaaacctct ctttttcttc     2100

tctttttcat ctcccaagag atcctcctct catgactaca gttgaatagg tggtttctat     2160

tggaagacat tcaggaattc aaggtgcatg tccataaatg gacttttttt gttgttgttc     2220

agagctggac cttgaatgat gcatccttct ctctgttgta accatgaata atgcaccctt     2280

catgctatag cctttaacga ttcacccttc ttattgtaac cttgaatgat tcacccttta     2340

tggtgtagcc ttgagtgacg cacccttcat gttgtagcct tcaatgatgc acactccatg     2400

ttatagcctt gaatgatata ccctttatgc tgcagccttt ctcttatggg gaaaagcctg     2460

cagatatcct gctgcttaac tgacaagtgt ggtgagaaat aagtagaaat ctaaagaggg     2520

gaagaccatt ttggacactt atctgcaagg cagatccaac acacttttcc agtagtcaag     2580

ctacttctaa ttttgttcag tatcaaaatg agaaacaggc ctgattctcc agcactcttg     2640

tcaacacaac ttccccccat atttatatat atacacacac atatatatct ttatatatat     2700

acacacatat atatctttat atatatatat ttatatatat atctttttgc atatatacat     2760

atatatgtat ctttatttcc tttgaaataa agataaatat agctgatttc tttggcttcg     2820

acacttacta tttgcatgac taagggaagc tagttaacct ttctgtgact catttccttg     2880

tccataaaat gggaatatta attgtacatg tcttatggat tggtgtgtga attcagttag     2940

cgagtgtaga atataactta tagatcaaag tagagtaaat ggaaagggct caactatggt     3000

gttgctactg ccattgttat tacaggcaca cagttcgagc tataatcatt tcaagggaaa     3060

ttcttatgtg tcagttctgg atcgaggtct gagattctgc atttcaaaca aacttccagg     3120

aatgctgctg cttcttggtc cacacttgga gaaataagtc agcagagagt cctctcgttt     3180

cctattgtac catgtctgtc ttttgtctcc tgcttattgg cctctgtaag gaactcacag     3240

ctgctataat aaagtaccaa aaactgggtg gcttaaaaca aaaaaaaaaa aaaaaa         3296


<210>  701
<211>  4166
<212>  DNA
<213>  homo sapiens

<400>  701
gtgcaaaata ttgtgcaagg cccgggtaca gaacaaggaa taataagaca cgccctgaag       60

gagtacatcg tctagtgagg gacagaccaa gcacgcaaaa caaattgcaa tataatgtga      120

taagttcttt aaaagaggta agagcaacgt gctttgggag cagagaagag ggagaaagca      180

gcatcttgcc tggatgagcc aggggacaca gaagagaagc ccactatctc atttaatctt      240

tacaactctc ttgcaaggtt ccctggttgt gaaaatacat gagataaatc atgaaggcca      300

ctatcatcct ccttctgctt gcacaagttt cctgggctgg accgtttcaa cagagaggct      360

tatttgactt tatgctagaa gatgaggctt ctgggatagg cccagaagtt cctgatgacc      420

gcgacttcga gccctcccta ggcccagtgt gccccttccg ctgtcaatgc catcttcgag      480

tggtccagtg ttctgatttg ggtctggaca aagtgccaaa ggatcttccc cctgacacaa      540

ctctgctaga cctgcaaaac aacaaaataa ccgaaatcaa agatggagac tttaagaacc      600

tgaagaacct tcacgcattg attcttgtca acaataaaat tagcaaagtt agtcctggag      660

catttacacc tttggtgaag ttggaacgac tttatctgtc caagaatcag ctgaaggaat      720

tgccagaaaa aatgcccaaa actcttcagg agctgcgtgc ccatgagaat gagatcacca      780

aagtgcgaaa agttactttc aatggactga accagatgat tgtcatagaa ctgggcacca      840

atccgctgaa gagctcagga attgaaaatg gggctttcca gggaatgaag aagctctcct      900

acatccgcat tgctgatacc aatatcacca gcattcctca aggtcttcct ccttccctta      960

cggaattaca tcttgatggc aacaaaatca gcagagttga tgcagctagc ctgaaaggac     1020

tgaataattt ggctaagttg ggattgagtt tcaacagcat ctctgctgtt gacaatggct     1080

ctctggccaa cacgcctcat ctgagggagc ttcacttgga caacaacaag cttaccagag     1140

tacctggtgg gctggcagag cataagtaca tccaggttgt ctaccttcat aacaacaata     1200

tctctgtagt tggatcaagt gacttctgcc cacctggaca caacaccaaa aaggcttctt     1260

attcgggtgt gagtcttttc agcaacccgg tccagtactg ggagatacag ccatccacct     1320

tcagatgtgt ctacgtgcgc tctgccattc aactcggaaa ctataagtaa ttctcaagaa     1380

agccctcatt tttataacct ggcaaaatct tgttaatgtc attgctaaaa aataaataaa     1440

agctagatac tggaaaccta actgcaatgt ggatgtttta cccacatgac ttattatgca     1500

taaagccaaa tttccagttt aagtaattgc ctacaataaa aagaaatttt gcctgccatt     1560

ttcagaatca tcttttgaag ctttctgttg atgttaactg agctactaga gatattctta     1620

tttcactaaa tgtaaaattt ggagtaaata tatatgtcaa tatttagtaa agcttttctt     1680

ttttaatttc caggaaaaaa taaaaagagt atgagtcttc tgtaattcat tgagcagtta     1740

gctcatttga gataaagtca aatgccaaac actagctctg tattaatccc catcattact     1800

ggtaaagcct catttgaatg tgtgaattca atacaggcta tgtaaaattt ttactaatgt     1860

cattattttg aaaaaataaa tttaaaaata cattcaaaat tactattgta tacaagctta     1920

attgttaata ttccctaaac acaattttat gaagggagaa gacattggtt tgttgacaat     1980

aacagtacat cttttcaagt tctcagctat ttcttctacc tctccctatc ttacatttga     2040

gtatggtaac ttatgtcatc tatgttgaat gtaagcttat aaagcacaaa gcatacattt     2100

cctgactggt ctagagaact gatgtttcaa tttacccctc tgctaaataa atattaaaac     2160

tatcatgtga cttcatgtaa tcaggctgaa catttctaca attactagat gtattagacg     2220

taagtatttt ctttagttaa accacccatg ttagaaatgt tttctgtaga atttataaac     2280

aactatcaat gcagacaatt taataagcct ggggatgatt tacttacagt aaacatttat     2340

caaattgtac atttgtgcta tcaacaatta ataagcaaat atgtgaaaat agtttctgtc     2400

ttctatgaag ttagatattt gatggttaaa acccctataa atcatagttt catatgggaa     2460

aaaataattg aaatacagtg taaatttaaa taatttatta agtatagcaa ataattgaaa     2520

tatggtggac taaattttgt catagaaata tgtgcaagtt atagtagtgg ctcacatgag     2580

aggtaatcaa ttctgctaat agtagcagaa tgagtgcagt ggaacatgaa aaacttgagg     2640

agataacagt tgaggtgggt ttccatagat gcataatagt tcaagagcaa gatttggtgg     2700

ggaggcacta ttcaagacag ggactaagtt caaaatccaa gacgtatgct gggacacacc     2760

tctgacaggt tggcataaag gaggcttaat caaactattt ttcttcttct gaaacagaag     2820

caataatttt catttacatt tgacatatcc cgaggtaata ttaacattag ggaaagttac     2880

tcttttccat ctttccacat tcttgcagga ccataaaatc tgaattttcc agtattttta     2940

ataagaggga agaaacctct ctttttcttc tctttttcat ctcccaagag atcctcctct     3000

catgactaca gttgaatagg tggtttctat tggaagacat tcaggaattc aaggtgcatg     3060

tccataaatg gacttttttt gttgttgttc agagctggac cttgaatgat gcatccttct     3120

ctctgttgta accatgaata atgcaccctt catgctatag cctttaacga ttcacccttc     3180

ttattgtaac cttgaatgat tcacccttta tggtgtagcc ttgagtgacg cacccttcat     3240

gttgtagcct tcaatgatgc acactccatg ttatagcctt gaatgatata ccctttatgc     3300

tgcagccttt ctcttatggg gaaaagcctg cagatatcct gctgcttaac tgacaagtgt     3360

ggtgagaaat aagtagaaat ctaaagaggg gaagaccatt ttggacactt atctgcaagg     3420

cagatccaac acacttttcc agtagtcaag ctacttctaa ttttgttcag tatcaaaatg     3480

agaaacaggc ctgattctcc agcactcttg tcaacacaac ttccccccat atttatatat     3540

atacacacac atatatatct ttatatatat acacacatat atatctttat atatatatat     3600

ttatatatat atctttttgc atatatacat atatatgtat ctttatttcc tttgaaataa     3660

agataaatat agctgatttc tttggcttcg acacttacta tttgcatgac taagggaagc     3720

tagttaacct ttctgtgact catttccttg tccataaaat gggaatatta attgtacatg     3780

tcttatggat tggtgtgtga attcagttag cgagtgtaga atataactta tagatcaaag     3840

tagagtaaat ggaaagggct caactatggt gttgctactg ccattgttat tacaggcaca     3900

cagttcgagc tataatcatt tcaagggaaa ttcttatgtg tcagttctgg atcgaggtct     3960

gagattctgc atttcaaaca aacttccagg aatgctgctg cttcttggtc cacacttgga     4020

gaaataagtc agcagagagt cctctcgttt cctattgtac catgtctgtc ttttgtctcc     4080

tgcttattgg cctctgtaag gaactcacag ctgctataat aaagtaccaa aaactgggtg     4140

gcttaaaaca aaaaaaaaaa aaaaaa                                          4166


<210>  702
<211>  10978
<212>  DNA
<213>  homo sapiens

<400>  702
atggtggagc cagggcaaga tttactgctt gctgctttga gtgagagtgg aattagtccg       60

aatgacctct ttgatattga tggtggagat gcagggcttg caactccaat gcctaccccg      120

tcagttcagc agtcagtgcc acttagtgca ttagaactag gtttggagac cgaagcagca      180

gttcctgtta aacaagaacc agagactgta cctactccag cactattaaa tgtgaggcag      240

cctccatcta ctacaacatt tgtgctgaat caaataaatc atcttccacc cttgggatct      300

acaattgtaa tgactaaaac accacctgta acaaccaaca ggcaaaccat cactttaact      360

aagtttatcc agactactgc aagcacacgc ccgtcagtct cagcaccaac agtacgaaat      420

gccatgacct ctgcaccttc aaaagaccaa gttcagctta aagatctact gaaaaataat      480

agtcttaatg aactgatgaa actaaagcca cctgctaata ttgctcagcc agtagcaaca      540

gcagctactg atgtaagcaa tggtacagta aagaaagagt cttctaataa agaaggagct      600

agaatgtgga taaacgacat gaagatgagg agtttttccc caaccatgaa ggttcctgtt      660

gtaaaagaag atgatgaacc agaggaagaa gatgaagaag aaatgggtca tgcagaaacc      720

tatgcagaat acatgccaat aaaattaaaa attggcctac gtcatccaga tgctgtagtg      780

gaaaccagct ctttatccag tgttactcct cctgatgttt ggtacaaaac atccatttct      840

gaggaaacca ttgataatgg ctggttatca gcattgcagc ttgaggcaat tacatatgca      900

gcccagcaac atgaaacttt cctacctaat ggagatcgtg ctggcttctt aataggtgat      960

ggtgccggtg taggaaaagg aaggacgata gcaggaatca tctatgaaaa ttatttgttg     1020

agtagaaaac gagcattgtg gtttagtgtt tcaaatgact taaagtatga tgctgaaaga     1080

gatttaaggg atattggagc aaaaaacatt ttggttcatt cgttaaataa gtttaaatac     1140

ggaaaaattt cttccaaaca taatgggagt gtgaaaaagg gtgttatttt tgctacttac     1200

tcttcactta ttggtgaaag ccagtctggc ggcaagtata aaactaggtt aaaacaactt     1260

ctgcattggt gcggtgatga cttcgatgga gtgatagtgt ttgatgagtg tcataaagcc     1320

aaaaacttat gtcctgttgg ttcttcaaag ccaaccaaga caggcttagc agttttagag     1380

cttcagaaca aattgccaaa agccagagtt gtttatgcta gtgcaactgg tgcttctgaa     1440

ccacgcaaca tggcctatat gaaccgtctt ggcatatggg gtgagggtac tccatttaga     1500

gaattcagtg attttattca agcagtagaa cggagaggag ttggtgccat ggaaatagtt     1560

gctatggata tgaagcttag aggaatgtac attgctcgac aactgagctt tactggagtg     1620

accttcaaaa ttgaggaagt tcttctttct cagagctacg ttaaaatgta taacaaagct     1680

gtcaagctgt gggtcatcgc cagagagcgg tttcagcaag ctgcagatct gattgatgct     1740

gagcaacgaa tgaagaagtc catgtggggt cagttctggt ctgctcacca gaggttcttc     1800

aaatacttat gcatagcatc caaagttaaa agggttgtgc aactagctcg agaggaaatc     1860

aagaatggaa aatgtgttgt aattggtctg cagtctacag gagaagctag aacattagaa     1920

gctttggaag agggcggggg agaattgaat gattttgttt caactgccaa aggtgtgttg     1980

cagtcactca ttgaaaaaca ttttcctgct ccagacagga aaaaacttta tagtttacta     2040

ggaatcgatt tgacagctcc aagtaacaac agttcgccaa gagatagtcc ttgtaaagaa     2100

aataaaataa agaagcggaa aggtgaagaa ataactcgag aagccaaaaa agcacgaaaa     2160

gtaggtggcc ttactggtag cagttctgac gacagtggaa gtgaatctga tgcctctgat     2220

aatgaagaaa gtgactatga gagctctaaa aacatgagtt ctggagatga tgacgatttc     2280

aacccatttt tagatgagtc taatgaggat gatgaaaatg atccctggtt aattagaaaa     2340

gaccacaaga aaaacaaaga gaaaaaaaag aagaaaagta tagatccaga ttctattcaa     2400

agtgccttat tagcatcagg tcttggatca aaacgaccta gtttttcatc tacaccagtt     2460

atctcacctg ctcctaacag tacaccagct aacagtaaca ccaacagtaa cagtagcctt     2520

ataacaagtc aggatgctgt ggaaagggct cagcagatga agaaagacct gcttgataag     2580

ctagaaaaat tagctgaaga cctcccccct aataccctgg atgaacttat cgatgaactt     2640

ggtggccctg agaacgttgc tgagatgact ggccgcaagg gacgggttgt gagcaatgat     2700

gatggaagca tatcttatga gtcaagatct gaacttgatg tgcctgtgga aatactaaac     2760

atcacagaaa aacaacgatt tatggatgga gataagaata ttgctatcat ctcagaagct     2820

gccagctcgg gtatttcatt acaagcagat aggagagcta aaaatcaaag gcgaagagtt     2880

catatgactt tagaattacc ttggagcgct gatagagcaa ttcaacagtt cggacgtact     2940

catagatcaa accaagttac tgctcctgag tatgtctttc tgatatctga actggcagga     3000

gaacaaagat ttgcatctat tgttgctaaa agacttgaga gtttgggggc acttacacat     3060

ggtgatagaa gggcaacaga atctagagat ctgagcaggt tcaactttga taataagtat     3120

ggaagaaatg ctttagaaat tgtcatgaaa tccattgtaa acttggattc tcctatggta     3180

tcaccacctc cagactatcc tggagaattt tttaaagatg ttcgacaagg actgataggc     3240

gttggcctga taaatgtaga agatcgctcg ggaattctta ctctcgataa agattataac     3300

aacataggaa aattcttaaa tagaatttta ggcatggagg tgcatcagca gaatgcgtta     3360

tttcagtatt ttgcggacac acttactgca gttgttcaaa atgccaaaaa aaatggaaga     3420

tatgatatgg gaatcttaga tcttggttct ggagatgaaa aagtgcggaa aagtgatgtt     3480

aaaaagtttc tgactccagg atattcaacc tctggccacg tagaattata cacaattagt     3540

gtagagaggg gaatgtcatg ggaggaagct accaagattt gggctgagct gacaggacca     3600

gacgatggct tttacttgtc attgcaaata aggaacaaca agaaaactgc catcttagtt     3660

aaagaagtga atcctaaaaa gaaacttttc ttagtttatc gaccaaatac tgggaagcag     3720

ctcaaattag aaatttatgc tgatctaaaa aagaaatata agaaggtcgt ctcagatgat     3780

gccctgatgc actggttaga tcagtataat tcatctgcag atacttgtac tcatgcttat     3840

tggcgcggca attgcaaaaa agcaagcttg gggctagttt gtgaaatagg tcttcgttgc     3900

cgtacatatt atgtattatg tggttcagtg ctgagtgtct ggacaaaagt tgagggtgtt     3960

ctagcatctg tcagtggcac aaacgtgaag atgcagatcg tgcggctaag aacggaagat     4020

gggcaacgga ttgtaggttt gatcattccg gcaaattgtg tgtctcctct tgtaaatctc     4080

ctatcaactt cagaccagtc tcaacagctt gcggtccaac agaaacagct atggcaacag     4140

catcaccctc agagcatcac caacttgagc aacgcatgaa gaacagacag gtttcaacat     4200

ggatggatct gaaatgctgt tgaagcatat catttgcata aaaatcaggg acagtttcca     4260

aagaattata tatttttttc agttgtgctc tctagttagt ttttttggga gtaaggacaa     4320

acctggaata gatagcaaaa ctgaaaatca gcagtgctga tggtggtaca tatgtctttc     4380

ctttagcttc tcccctgata attcccatct gcttttactt cgggtgagca gagggggatg     4440

tgtgtgtgcg tgtgtgtcag tctgtttgtg agtgtgttaa aggctacaga ccacagttgg     4500

tttaaaatgc ttggaacttc ccaaactggc tttactttat gtttatacag tgctcagggt     4560

taacgcagta catccatgcc attgctgtgg gaggtatccc cggatgcatg tgttttgagt     4620

ctataaatat agaaaatata tattggtttc tttttccaac ttaataggtt tattaaagca     4680

tgaaatgaaa ggttgcatat catgcattca ggttattttc taatttttgt tctgacagtg     4740

catgtctttg gaagcatgct gaaacaagat taacacagga gtcgagtaac agagagaaac     4800

atttgttaga tgtacagcat tggttattgc atttttatag tgtttatacc tgggtattgc     4860

ttcaaaccct gcagacccct ccttcccctt ctccctgccc tgggtttctg gtcaaggtaa     4920

tgaatacata catttttctg tgataaaact cttaaaagtt aattttaatg tattaatagt     4980

attcctaatg tgtgctgcag aaatggctat gagcctctta aatttacatt tgcaacttaa     5040

aggtagtttt agaaggaagt acaaattggc tttcatcttg caaacaatcg ttttttactt     5100

cattatctta atttgctttg tcactcataa aaaggaaacc atacctgagt tgtagacaat     5160

gaggaaacac ttgaggcttc tgctgtgtgt tcttttgtta ttgttgttat tgttgttact     5220

cagtaacttg aatattgttt aatgtgttgt aagacgtaga gtttatctca agctgttaaa     5280

aatggtaatg tacaaatgtg aatagacact tatctatata atatgggtaa gttttgtttc     5340

gcctataata gatgtttata aaaacaagtg aggggacagt tggtcttttt atcttttctt     5400

tctttttctt tcttttcttt ttttcttttt tttttttttt tttttttttt ttgcttccac     5460

aggttgcact attgaaaaat cgagattgta taaacctggt aaaaagctgc aagatgccaa     5520

aatcttgtag atgtcaaata aaaagttatt atactaacaa gaagtggact cttgtttagg     5580

ccctcactgg tgaccttcag aagtagtctg tgacggggac tcagcagaat ttgtgtgttg     5640

tctcagcatt ccaggtagcc ttatagtttg gcttaaaact tatccctaaa atgtaagatg     5700

gcattgaggg aaagggtata atgatagtac ttctgaatgt tttttaagtt gaattgtttg     5760

taaacttctt gcagaattgg gtgagatgtg tgttaaaact gacaaacctg gctgaaagct     5820

tagggcgttc atcctcttgt gtctccttta gcctgagttt ggttatgtca agcttaccgt     5880

aagttttctt aggatttatt tattcttggt gcctaaaaga ataaattgaa agtactttct     5940

gttctttggc acattttgcc cagcggatgc aacttctatc ctcagtccag ttcatatatc     6000

tcaggcagtg atccattttg tatcagccag tttcccttgt tagggccgct agacccggct     6060

ggcagccaag agcagcactc tccccacctt cagcagaact tctcagctca tgtgtgtgtt     6120

tttaaaagca gtaggcagct tccatcagca atggaagtgt cccccactcc agtggtggag     6180

gtgcagtcgc tggacctgag gaagtgggga agcattacaa accctcctgc agtaagaatg     6240

gcagagttgg gaaggatctt ctctcgcagg ctgttggccc aactcctctt ttctgtgtat     6300

gagggcatct tagtttttta tggcgttttc aaagcagcat atgaggattc ttagcatgca     6360

gctaagtgac aacccccatg gcctatgatg taatgtttgc tctggactag ccatcttgat     6420

aaataggagt gtatgtatct taggttcttt gtagaacagc tatttttttt tctcattaaa     6480

aaggcctctg aaagccctct caaaatggac ctcacaaagg caaccagtgt gaatggatgg     6540

gagctggggt gctgcatgcc caggctggtc atggtgtgtg cagcacccag agagttgcac     6600

ccaccccttc ttcaggtgga catccgacct ttacactgtg gtcttgcaaa aatcagcgag     6660

ttagtttggc cgccctgtga agcttcagca ttcaaggtcc tcttctgtta aaacccaact     6720

cgtagccggg cgtggtggct cactcctata atcccagcac ttcgggaggc caaggcaggt     6780

gcatcacttg aggccaggag ttcgagacca gcctggtcca catggcaaaa ccccatctgt     6840

accaaaaaat acaaaaaatt tgccgctgac ttctgtaaaa taggtccatt cattgcagga     6900

tctaaatgcc acacctgaat tcagaggcct tgtttaatta accccatgtc cactttgcct     6960

ctgcaatgcc tttttctttt tagcaatatg gctctgagca caaagatttg gttggaaatc     7020

atgttcgtgt tttcagagtt tacagcgtca attgtactga aaaccacttc cagagtctaa     7080

agcagctcag atgttatctc tgggggaatt agtgttcccc tcatttagca acctccatac     7140

cacaaggtct ctgtctgtag ttactgggat tatccagata cactatcaat gatacaaatt     7200

cataggagta ttaatgcatt tctttaaaca caacttgatt aagaagcaaa tatgttaagc     7260

agttttcttt ttctgctgct aaattacagt tagacacttc agtatcttct ctttacatgt     7320

gtatataaat tagtaagaac ctgcatccaa agcaatgtag tgtgtgtatg tatctatata     7380

tatttattct aactcagcac ttcagaagcc tttttgagtt acaacaatat tttagtttgc     7440

ctcatctgta gaggtaaaat ttctatatta ccaagctcca gaggaatatg atattttaca     7500

ggcacaattt tctggctgta gtccctgggg cattcatttg ctggcctcca tgggatgctg     7560

ttagaacaat tgttagccgg caagagaaga aaggctacca ggacagcatt tataattgta     7620

gaatgggagc cttcttccct ctcccctcca ctttcatttt agcatgagat aaaaaaatag     7680

attggaaatg attgttgcat ctcacttcat ggaagtaggg gcagaagttc cctctggatc     7740

cttttcttga caagcagtca agaggaaggt ccccatacac atgtacctgt gtgatacttg     7800

gtagtttcta agaatggtgc tacataagcg ttgctgttag gctgggatcc tattaatgaa     7860

cgtttgatta gttcaggcct cccaatggca aaggcagaca ccgtggagat ggacatttac     7920

tgactcccct tctgtgtggc ttcggtctcc ctggctaaca ccacacctgt gcgtactgcg     7980

ctcggcccac tttgctgcag aaacgtagca agcgtttcat gtcagggcta cagctgagag     8040

caaaaactgc aaaaaaaaaa aaaaatgtct cattgaatgc cagttgtctg atacaaatgc     8100

agtgtctttt aagtgacaga aacacaccta aatacctgca actcaagctc gctagcattt     8160

tttttttgag tacttgagat aaaatccaaa acccaccctc taattttgtg ctgtatttat     8220

atatatgtac ataaatgtat atatagagaa atgttgagtt cttctggatt ctgaatgtaa     8280

ataattcttg taaattggga ctctgcccac ctgtttctcc cttttccctc ttcccttcag     8340

ctctatttat tcttttcttg actttcccat atggggcatc ttatgacttt tttttttttt     8400

tttttttaag aaaagtatgg aaaacttttc atttagaaaa gtatttgttc ctgtatttta     8460

gaattcagtt ttgcatcttt gctgtagaat tcctgttttg tgttaatgtt ttttactatg     8520

tcttattgtg ttgtgtgcaa tgcattgtac tggggggatg cacttgagtg ccatttctga     8580

tactgtcatt gtatgactgc tgatgctcgt ttatgttgtt ctttggaagc tatagtgagc     8640

ctgatgtttt cacattttaa aaaatgcttc ctgagacttc tttaagctcc tctaacttct     8700

tcagtgcatt tgggatcaaa cttagctctt agatcagcaa acctgacttg cttctacttt     8760

tgcaattttt caggccttac catatttctt atctctgtct tcccacctga taggaaaatc     8820

ttgcagattt gaaacagtgg tttctggcct gctgctgcag caaattccct atgtttattt     8880

aagaagtcgg gcctatgctt ttaacctaca aatgatgagt aatttacttg caatgaacac     8940

aggtagcctg ctgctgttta taacctgttg aggatattta tagcaggcag gaggcaggcc     9000

tagtgtgtta ttgacaggtg actttagaga atgtacattg gccgggtgcg gtggctcacg     9060

cctgtaatcc cagcactttg ggaggccgag gcgggcggat catgaggtca ggagattgag     9120

accatctcct ggctaacacg gtgaaacccc gtctctacta aaaatacaaa aaaaaaaaaa     9180

acttagccag gcgtggtggc gggtgcctgt agtcccagct actcaggagg ctgaggcagg     9240

agaatggcat gaacctggga ggcagagctt gcagtgagcc cagatcgcgc cactgcactc     9300

cagcctgggc aacagaccga gactccgtct cgaaaaaaaa aaaagagaga gaatgtacat     9360

taaggaacaa ttgtcctcca aaagagagcc aagcaactgc tctggagcct cctaggctga     9420

ctctgctgga gggtgagaca agcagattcc cattgcagca ctggtccctg gggtaccctg     9480

aacggctgtg ctctccaccc ttgtatcggt gagtggatct tgtctacatc agccgtaagc     9540

ctagaagcag agcgggatcg aggcgttttt aataattcga gttgggaaga cccggatggt     9600

tcatcaaaat gatggtgttg agcacccggg aggcagacat tgggtatttg ttcacaattt     9660

tgcacctgta agaaaatgtt cctttataac tttcaaggat tgccgtgagc gtctttgggg     9720

ccttttcatt catgtacaag tttcattcat tactattcaa cttggtagac ttggtgaaaa     9780

atgtaaaagc attctgtatt tggatcagtc ttgggaacta aatttgtcgt gaattggggc     9840

ctgtcacaga ttgcctccag tgtgcatcct ccacgcagac cctccttgct cagtctccct     9900

ctggcgccca tggggaagcc gtgctgtggt tggcagtgcg gccatctggg ctgccgcaac     9960

gtggcagggc accgtccagc aagactgccc cttagtgcag ggctaagcaa ggaaaagaag    10020

aagcccaaaa aggcgggttc tttttgatac ttgtaattca ggcgtcctcc agagtgaagg    10080

ccactctgca ggcccctggt gagaacctgt ctggcttttc cactgcgggc ccctaaccag    10140

taccctgccc ttgtggccca tttgtgcctg ggcagatgtt tctggccagc agacactgaa    10200

ggcctttttg ctgtgacagt atttatggca ctgaagagga taaagaagct tgagccctct    10260

ttctgactcc cactttatgg ggcagagaga gctttttttc tacatagcac attgcagtct    10320

caccgctatc agaaaaatat cctgttcatg gtttatactg aatttgcaaa ctactgatat    10380

gatttttcaa taaccacttg tatcttccat catccatgag aggtgggaag aggtacactg    10440

tatctctgca ataaaacttt ggccaggttc tacctcctct gagcaaagga tacttttcta    10500

tgtaggtgta gatggttctc ctttactaat ctgacatggt gcatctggag acaacatctg    10560

atgggatcca aagacaactt gaaacaaagg tggatgtcag ctcttggtgt gttttcattt    10620

ggttctcttt tttaaatctc ccttttgtta tcgctcctgt tgtagcgtgt ccatcagtgt    10680

gtgaagggtg cgccctgttc caatgatact gcattgctgc atccagcctt tcgtgggagc    10740

acggtaccaa gcgtccggaa ttgattatcc caatcatttt tgatatgtaa ctgaaaaatt    10800

tggtctcatg caataaaaat gtactggctg cattttagca aggtttattt actcttgcaa    10860

gtaaaaacga tcaaccgtga agcgtaacaa attctgtatt tagttttttt ttctgttgtg    10920

gtggtttttg ttttgttttt tgtttttgta agattctaaa taaattaaat acgagtca      10978


<210>  703
<211>  2586
<212>  DNA
<213>  homo sapiens

<400>  703
ataaagtgat tattttctct tggttctttg aaaaacctcg cttgtgctgg ggtttgtggc       60

tgaacccggt gacgtcagtg tggcagtgcg gagtcaggcg cagcggctcc ctataagcag      120

aggagctgtc cgtgtgctga aacggcccga gaagctcgcc cggagaacgg ggaggaatat      180

gctgtggagc tcctctgcca tataaacaaa aagaggaaat ctttcaaaca tggctgaagc      240

aaagacccac tggcttggag cagccctgtc tcttatccct ttaattttcc tcatctctgg      300

ggctgaagca gcttcatttc agagaaacca gctgcttcag aaagaaccag acctcaggtt      360

ggaaaatgtc caaaagtttc ccagtcctga aatgatcagg gctttggagt acatagaaaa      420

cctccgacaa caagctcata aggaagaaag cagcccagat tataatccct accaaggtgt      480

ctctgtcccc cttcagcaaa aagaaaatgg cgatgaaagc cacttgcccg agagggattc      540

actgagtgaa gaagactgga tgagaataat actcgaagct ttgagacagg ctgaaaatga      600

gcctcagtct gcaccaaaag aaaataagcc ctatgccttg aattcagaaa agaactttcc      660

aatggacatg agtgatgatt atgagacaca gcagtggcca gaaagaaagc ttaagcacat      720

gcaattccct cctatgtatg aagagaattc cagggataac ccctttaaac gcacaaatga      780

aatagtggag gaacaatata ctcctcaaag ccttgctaca ttggaatctg tcttccaaga      840

gctggggaaa ctgacaggac caaacaacca gaaacgtgag aggatggatg aggagcaaaa      900

actttatacg gatgatgaag atgatatcta caaggctaat aacattgcct atgaagatgt      960

ggtcggggga gaagactgga acccagtaga ggagaaaata gagagtcaaa cccaggaaga     1020

ggtgagagac agcaaagaga atatagaaaa aaatgaacaa atcaacgatg agatgaaacg     1080

ctcagggcag cttggcatcc aggaagaaga tcttcggaaa gagagtaaag accaactctc     1140

agatgatgtc tccaaagtaa ttgcctattt gaaaaggtta gtaaatgctg caggaagtgg     1200

gaggttacag aatgggcaaa atggggaaag ggccaccagg ctttttgaga aacctcttga     1260

ttctcagtct atttatcagc tgattgaaat ctcaaggaat ttacagatac ccccagaaga     1320

cttaattgag atgctcaaaa ctggggagaa gccgaatgga tcagtggaac cggagcggga     1380

gcttgacctt cctgttgacc tagatgacat ctcagaggct gacttagacc atccagacct     1440

gttccaaaat aggatgctct ccaagagtgg ctaccctaaa acacctggtc gtgctgggac     1500

tgaggcccta ccagacgggc tcagtgttga ggatatttta aatcttttag ggatggagag     1560

tgcagcaaat cagaaaacgt cgtattttcc caatccatat aaccaggaga aagttctgcc     1620

aaggctccct tatggtgctg gaagatctag atcgaaccag cttcccaaag ctgcctggat     1680

tccacatgtt gaaaacagac agatggcata tgaaaacctg aacgacaagg atcaagaatt     1740

aggtgagtac ttggccagga tgctagttaa ataccctgag atcattaatt caaaccaagt     1800

gaagcgagtt cctggtcaag gctcatctga agatgacctg caggaagagg aacaaattga     1860

gcaggccatc aaagagcatt tgaatcaagg cagctctcag gagactgaca agctggcccc     1920

ggtgagcaaa aggttccctg tggggccccc gaagaatgat gataccccaa ataggcagta     1980

ctgggatgaa gatctgttaa tgaaagtgct ggaatacctc aaccaagaaa aggcagaaaa     2040

gggaagggag catattgcta agagagcaat ggaaaatatg taagctgctt tcattaatta     2100

ccctactttc attcctccca ccccaagcaa atcccaacat ttctcttcag tgtgttgact     2160

tctatcctgt taacactgta atatctttaa atgatgtaca ggcagatgaa accaggtcac     2220

tggggagtct gcttcatttc ctctgagctg ttatcttgtg tatggatatg tgtaaatgtt     2280

atgactcctt gataaaaaat ttattatgtc cattattcaa gaaagatatc tatgactgtg     2340

tttaatagta tatctaatgg ctgtggcatt gttgatgctc acatatgata aaaaagtgtc     2400

ctataattct attgaaagtt tttaatattt attgaattat tttgttactg tctgtagtgt     2460

tttgtggagt actggaccaa aaaaataaag cattataaat atatagtttt atttataagg     2520

ccttttctat tgtgtgtttt actgttgatt aataaatgtt atttctggac aaaaaaaaaa     2580

aaaaaa                                                                2586


<210>  704
<211>  1362
<212>  DNA
<213>  homo sapiens

<400>  704
tttatagacg gtgattgggc tgctggaagc tgggaggggt gagggactgg agggagtcgg       60

agaaaaagct gacctaatga aactgtggca acgtcagcgc ttgaggcttg aagagggaga      120

caagctaaaa gaggatatcc agttgtttca tgatggcatt tgcacctcca aaaaacacag      180

atggtcccaa aatgcagaca aagatgagca cctggacacc cctaaaccat cagctattga      240

atgaccgggt atttgaagaa agaagagccc tgcttggcaa atggtttgac aaatggacag      300

actctcaaag aagaagaatc ctcacaggcc tgttggagcg ctgctcgctg tcccagcaaa      360

agttctgctg tcgaaagctt caagagaaaa ttccagcaga agccctggac tttacaacca      420

agcttccaag ggtgttatct ttatacatct tttctttcct ggaccctcgg agcctttgtc      480

gttgtgcaca ggtgtgctgg cattggaaga accttgctga gctggaccag ctctggatgc      540

tgaaatgttt acggtttaac tggtacatca atttctctcc aactcccttt gagcagggga      600

tctggaagaa gcactatatt caaatggtga aagaacttca tattaccaag cctaagacac      660

ccccaaagga tggatttgta atcgctgacg ttcaactagt tacaagcaat tctccagagg      720

aaaaacagtc ccctttatca gcttttcggt cctcttcctc tttaagaaag aagaataact      780

caggggagaa agcacttcca ccctggcgat cttctgataa gcacccaaca gatatcattc      840

gttttaatta cctagacaac cgtgacccca tggagactgt ccagcaagga agaagaaaaa      900

gaaaccaaat gaccccagac ttcagccgac agtcacatga taagaaaaat aaattgcagg      960

acagaactag gctaagaaaa gcacaatcaa tgatgtcgag gagaaatccc ttcccactat     1020

gtccctaagt gccagctctc ccctaaaagt tccagctcat ctcgcctggc ctccccctga     1080

gtcagtggga ctcccagaca ctgccaccac agctgaaatt ctcatgcagc atcctcacag     1140

gcaccctggg ccccaagcat gactcatcca ggttccagag ccaaagtgga ctgaacatgg     1200

aaagactttt attatagaaa tgacaagatg ctttgcacag tggagagctg aatttacttg     1260

gctcccatta gaaactcttt cagcttaagt acttattgtg gtagtgagtc ctacggtatt     1320

tcagtaaaaa ggaattcatg gcataaaaaa aaaaaaaaaa aa                        1362


<210>  705
<211>  3995
<212>  DNA
<213>  homo sapiens

<400>  705
ccctcggtgc gcgggcacag cagccaggct gccggagagc tgatctcggg gattcgggtg       60

cggagccctt ggcctggagg cgatatgggt ggtccgtggc ccggttcagt cgcttgcagc      120

agcccgggga acaggcctgt ctggccctga gggagtcccc tttctgaagc tgtggtgctt      180

ggacgacctg ctctctacat tgctgggcac ctgtaggtgt ccctcgagag ctcagttttg      240

aggttcaagt cagtgtggcc atgaaggggc tgcctattgg gctgatgctg tgaccctgga      300

gtctgcctct cctgccagtc cccctgcccg gaacatgtgg ctgcggcttg gcccgccctc      360

gctgtccctg agccccaagc ccacggttgg caggagcctg tgcctcaccc tgtggttcct      420

cagtttggcg ctgagggcca gtacccaggc cccagcaccc acagtcaaca ctcactttgg      480

gaagctaagg ggtgcccgag taccactgcc cagtgagatc ctggggcctg tggaccaata      540

cctgggggtg ccctacgcag ctcccccgat cggcgagaaa cgtttcctgc cccctgaacc      600

acccccatcc tggtcgggca tccggaacgc cacacacttt cccccagtgt gcccccagaa      660

catccacaca gctgtgcccg aagtcatgct gccggtctgg ttcactgcca acttggatat      720

cgtcgctact tacatccagg agcccaacga agactgtctc tacctgaacg tctatgtgcc      780

gacggaggat gtaaagcgga tttccaagga atgcgcccga aagcccaaca agaaaatttg      840

taggaaagga ggatccggcg ctaagaaaca gggcgaggac ttagcggata atgacgggga      900

tgaagatgaa gacatccggg acagtggtgc taaacccgtc atggtctaca tccacggagg      960

ctcttacatg gaagggacag gcaacatgat tgatggcagc atcctcgcca gttatggcaa     1020

tgtcatcgtc atcaccctca actatcgggt tggagtgcta ggtttcctga gtactggaga     1080

tcaggctgcc aagggcaact atgggctcct tgaccagatc caggccctcc gctgggtgag     1140

cgagaatatt gccttcttcg ggggagaccc ccgccggatc actgtctttg gctcgggcat     1200

tggtgcatcc tgcgtcagcc tcctcacgtt gtcacatcac tcagagggac ttttccagag     1260

agccatcatc caaagtggct ctgctctgtc cagctgggct gtgaactacc aaccagtgaa     1320

gtacaccagc ctgctggcag acaaagtggg ctgtaatgtg ctggacaccg tggatatggt     1380

ggactgtctt cggcaaaaga gtgccaagga gctggtagag caggacatcc agccagcccg     1440

ctaccacgtg gcctttggcc ctgtgattga tggtgatgtc attcctgatg accctgagat     1500

cctcatggag cagggcgagt tcctcaacta tgacatcatg ctaggtgtca accagggcga     1560

gggtctcaag tttgtggaag gggtggtgga ccctgaggat ggtgtctctg gcactgactt     1620

tgactattcc gtctccaatt ttgtggacaa tctgtatggc tatcctgagg gtaaggacac     1680

cctgcgagag accatcaagt tcatgtatac agactgggca gaccgtgaca accctgagac     1740

ccgccgtaaa acactggtgg cactcttcac tgaccaccag tgggtggagc cctcagtggt     1800

gacagccgat ctgcatgccc gctacggctc gcctacctac ttctacgcct tctatcatca     1860

ctgccagagc ctcatgaagc ctgcttggtc agatgcagct catggggatg aagtacccta     1920

tgtttttggg gttcctatgg taggccccac tgaccttttc ccctgcaact tctccaagaa     1980

tgatgttatg ctcagtgctg tcgtcatgac ctattggacc aactttgcca agactgggga     2040

tcccaacaag ccggtccccc aggacaccaa gttcattcac accaaggcca accgctttga     2100

ggaagtggcc tggtccaaat acaatccccg agaccagctc taccttcaca tcgggctgaa     2160

accaagggtc cgagatcatt accgggccac taaggtggcc ttttggaaac atctggtgcc     2220

ccacctatac aacctgcatg acatgttcca ctatacgtcc accaccacca aagtgccgcc     2280

tccggatacc acccacagct cccacatcac ccgcaggccc aatggcaaga cctggagcac     2340

caagcggcca gccatctcac ctgcctacag caacgagaat gcccaggggt cctggaacgg     2400

ggaccaggat gcagggccac tcctggtgga gaaccctcgt gactactcca ctgaattaag     2460

tgtcaccatc gccgtggggg cctccctcct gttccttaac gttctggcct tcgctgccct     2520

ctactaccgt aaggacaaac ggcgccagga gcccctgcgg cagcctagcc ctcagcgggg     2580

agccggggcc ccggagttgg gagctgctcc agaggaggag ctggcagcat tacaactggg     2640

ccccacccac cacgagtgtg aggccggtcc cccccatgac acgctgcgcc tcactgcatt     2700

gcccgactac accctgaccc tgcggcgctc cccggatgac atcccactca tgacccccaa     2760

caccatcact atgatcccca actccctggt agggctgcag acattgcacc cctataacac     2820

ctttgccgca gggttcaaca gtaccgggct gccccactca cactccacta cccgggtata     2880

gctccaactc agagcacagc caatctccag gctccctccc tcccagatcc aggaacacat     2940

gcacacacac acacacacac acgcagacac acacacacac acacatatat gtatacgcac     3000

gcacccacac cctacagcag atccacctgc acaaacatag acagatgtgg acatgcaccc     3060

gcatgtacaa aaacacaaat acggaagtaa acctgaacaa accctttaaa tggggacgca     3120

gatgagtcct cggtaaaccg aggacccatg aaacagcagc tgaagccagc tccctgaatc     3180

tgaccacaga cactcctggg gggcctgaaa gcaacagctg gacaccccct tggtgctcgc     3240

cttcggcctc tcttggaact gcaccaccga ccaactccag acttgggagc tttaaagagc     3300

aggatagctc ttcctcccca ggacttggtc ttttttctgg gtcttgtttt gttgattttt     3360

cttttttaat tttggaacaa atgcttttcc aacccatgag tgctaagagc ctctggaagg     3420

gagggcttca ggcccgaagg tctctctggc tctaggaccc ccagtgctca cacaatcaga     3480

ccaaggaaca agacccccag gaaggaaaca gatttaagca agaccatggg gtggaaggag     3540

aaaggggcta gcactggatg gagctggagg gtcgtagggg agagatctcc aactctctct     3600

gtgtccgtgt ggagggctgc agagcctgca gggtgacctg cttccccaaa ggccaacagc     3660

attggcctgg ccagaccagg tgaccttaga tttggtgaac aacgtactat ggaagccaca     3720

tcactattgg gcccccaggt ctgatctggg ttttgcctct gcccttgggg aaatgctatc     3780

agaaattcgc cccattttct ttacagtctt ttgtgtctgt catttctctt tcaaaaaggc     3840

ggtgtttttt gttgttgttg gttttttttt ttttttaaag aaaagttctt aaaacactaa     3900

cggaaaccca tggagtttgt cctttgtaaa aattttaaac acagtgtctt gatataaaaa     3960

taaaaaatcc agttagcact cccaaaaaaa aaaaa                                3995


<210>  706
<211>  3817
<212>  DNA
<213>  homo sapiens

<400>  706
tttttttccc cgcctcccaa ccgtgaggtg ttgggtttgg gggacgctgg cagctgggtt       60

ctcccggttc ccttgggcag gtgcagggtc gggttcaaag cctccggaac gcgttttggc      120

ctgatttgag gaggggggcg gggagggacc tgcggcttgc ggccccgccc ccttctccgg      180

ctcgcagccg accggtaagc ccgcctcctc cctcggccgg ccctggggcc gtgtccgccg      240

ggcaactcca gccgaggcct gggcttctgc ctgcaggtgt ctgcggcgag gcccctaggg      300

tacagcccga tttggcccca tggtgggttt cggggccaac cggcgggctg gccgcctgcc      360

ctctctcgtg ctggtggtgc tgctggtggt gatcgtcgtc ctcgccttca actactggag      420

catctcctcc cgccacgtcc tgcttcagga ggaggtggcc gagctgcagg gccaggtcca      480

gcgcaccgaa gtggcccgcg ggcggctgga aaagcgcaat tcggacctct tgctgttggt      540

ggacacgcac aagaaacaga tcgaccagaa ggaggccgac tacggccgcc tcagcagccg      600

gctgcaggcc agagagggcc tcgggaagag atgcgaggat gacaaggtta aactacagaa      660

caacatatcg tatcagatgg cagacataca tcatttaaag gagcaacttg ctgagcttcg      720

tcaggaattt cttcgacaag aagaccagct tcaggactat aggaagaaca atacttacct      780

tgtgaagagg ttagaatatg aaagttttca gtgtggacag cagatgaagg aattgagagc      840

acagcatgaa gaaaatatta aaaagttagc agaccagttt ttagaggaac aaaagcaaga      900

gacccaaaag attcaatcaa atgatggaaa ggaattggat ataaacaatc aagtagtacc      960

taaaaatatt ccaaaagtag ctgagaatgt tgcagataag aatgaagaac cctcaagcaa     1020

tcatattcca catgggaaag aacaaatcaa aagaggtggt gatgcaggga tgcctggaat     1080

agaagagaat gacctagcaa aagttgatga tcttccccct gctttaagga agcctcctat     1140

ttcagtttct caacatgaaa gtcatcaagc aatctcccat cttccaactg gacaacctct     1200

ctccccaaat atgcctccag attcacacat aaaccacaat ggaaaccccg gtacttcaaa     1260

acagaatcct tccagtcctc ttcagcgttt aattccaggc tcaaacttgg acagtgaacc     1320

cagaattcaa acagatatac taaagcaggc taccaaggac agagtcagtg atttccataa     1380

attgaagcaa aatgatgaag aacgagagct tcaaatggat cctgcagact atggaaagca     1440

acatttcaat gatgtccttt aagtcctaaa ggaatgcttc agaaaaccta aagtgctgta     1500

aaatgaaatc attctacttt gtcctttctg acttttgttg taaagacgaa ttgtatcagt     1560

tgtaaagata cattgagata gaattaagga aaaactttaa tgaaggaatg tacccatgta     1620

catatgtgaa ctttttcata ttgtattatc aaggtataga cttttttggt tatgatacag     1680

ttaagccaaa aacagctaat ctttgcatct aaagcaaact aatgtatatt tcacatttta     1740

ttgagccgac ttatttccac aaatagataa acaggacaaa atagttgtac aggttatatg     1800

tggcatagca taaccacagt aagaacagaa cagatattca gcagaaaact ttttatactc     1860

taattctttt tttttttttt tttgagacag agttttagtc ttgtttccca ggctggagtg     1920

caatggcaca atcttggctc actgcaacct ccgcctcctg ggttcaggca attttcctgc     1980

ctcagcctcc caagtagctg ggattacagg cacccaccac catgcccagc taatttttgt     2040

atttttaata gagagctaat aattgtatat ttaataaaga cgggtttcac catgttggcc     2100

aggctggtct tgaactcctg acctcaggtg atcctcctgc attggcctcc caaagtgctg     2160

gaattccagg catgagccac tgcgcccagt ctacacacta attcttgtta gcccaacagc     2220

tgttctgttc tatctacccc tcatttcacg ctcaaggagt catacctaga atagttacac     2280

acaagaggga aactggaagc caaacactgt acagtattgt gtagaaagtc acctccctac     2340

tccttttatt ttacatgagt gctgatgtgt tttggcagat gagctttcag ctgaggcctg     2400

atggaaattg agataacctg caaagacata acagtattta tgagttatat cttagttctt     2460

gaaattgtgg aatgcatgat tgacaatata tttttaattt ttattttttc aagtaatacc     2520

agtactgttt aactatagcc agaactggct aaaattttta tattttcaga gttgaagttg     2580

gtgaagacat tcatgattta aacaccagat cctgaaaggg gttaaatcta ctttgaaatg     2640

aatctgcaat cagtatttca aagcttttct ggtaatttta gtgatcttat ttgattagac     2700

tttttcagaa gtactaaata aggaatttta acaggttttt attaatgcac agataaatag     2760

aagtacagtg aggtctatag ccattttatt aaaatagctt aaaagtttgt aaaaaaatga     2820

atctttgtaa ttacttaata tgttagttaa gaacccgtca agcttatatt tgctagactt     2880

acaaattatt ttaaatgcat ttatcttttt tgacactatt cagtggaatg tgtaagctag     2940

ctaattcttg ttttctgatt taaagcactt ttaaatctta tcctgccccc taaaaacaaa     3000

aggttttgat cacaagggga aatttaagat tgttaaccct gtttttcaga agggctactg     3060

ttaattgcac ataaacatga aatgtgtttt cccctgtgta ctaacacatt ctaggcaaaa     3120

ttcaaactta tagtggtaaa gaaacaggtt gttcacttgc tgaggtgcaa aaattcttaa     3180

gacttctgtt tgaaattgct caatgactag gaaaagatgt agtagtttac taaaattgtt     3240

tttctaccat atcaaattaa acaattcatg cctttatagg gtcaggccta caatgaatag     3300

gtatggtggt ttcacagaat tttaaaatag agttaaaggg aagtgatgta catttcgggg     3360

gcattagggt agggagatga atcaaaaaat acccctagta atgctttata ttttaatact     3420

gcaaaagctt tacaaatgga aaccatgcaa ttacctgcct tagttctttt gtcataaaaa     3480

caatcacttg gttggttgta ttgtagctat tacttataca gcaacatttc ttcaattagc     3540

agtctagaca ttttataaac agaaatcttg gaccaattga taatatttct gactgtatta     3600

atattttagt gctataaaat actatgtgaa tctcttaaaa atctgacatt ttacagtctg     3660

tattagacat actgttttta taatgtttta cttctgcctt aagatttagg ttttttaaat     3720

gtatttttgc cctgaattaa gtgttaattt gatggaaact ctgcttttaa aatcatcatt     3780

tactgggttc taataaatta aaaattaaac ttgtttc                              3817


<210>  707
<211>  4304
<212>  DNA
<213>  homo sapiens

<400>  707
cccgccccgt cgcactcaga gagctgggct ggagctccaa gcggaaaccg cgggagccga       60

gcccagctag gaatgcagac ctcctgaaaa ccaagccgag gactgcgggg tccggtgtcc      120

acgcagagtg tcagcttcct ctggtgcaac cagcaagtct tccagtatga atcccacaga      180

aaccaaggct gtaaaaacag aacctgagaa gaagtcacag tcaaccaagc tgtctgtggt      240

tcatgagaaa aaatcccaag aaggaaagcc aaaagaacac acagagccaa aaagcctacc      300

caagcaggca tcagatacag gaagtaacga tgctcacaat aaaaaagcag tttccagatc      360

agctgaacag cagccatcag agaaatcaac agaaccaaag actaaaccac aagacatgat      420

ttctgctggt ggagagagtg ttgctggtat cactgcaata tctggcaagc cgggtgacaa      480

gaaaaaagaa aagaaatcat taaccccagc tgtgccagtt gaatctaaac cggataaacc      540

atcgggaaag tcaggcatgg atgctgcttt ggatgactta atagatactt taggaggacc      600

tgaagaaact gaagaagaaa atacaacgta tactggacca gaagtttcag atccaatgag      660

ttccacctac atagaggaat tgggtaaaag agaagtcaca attcctccaa aatataggga      720

actattggct aaaaaggaag ggatcacagg gcctcctgca gactcttcga aacccatagg      780

gccagatgat gctatagacg ccttgtcatc tgacttcacc tgtgggtcgc ctacagctgc      840

tggaaagaaa actgaaaaag aggaatctac agaagtttta aaagctcagt cagcagggac      900

agtcagaagt gctgctccac cccaagagaa gaaaagaaag gtggagaagg atacaatgag      960

tgatcaagca ctcgaggctc tgtcggcttc actgggcacc cggcaagcag aacctgagct     1020

cgacctccgc tcaattaagg aagtcgatga ggcaaaagct aaagaagaaa aactagagaa     1080

gtgtggtgag gatgatgaaa caatcccatc tgagtacaga ttaaaaccag ccacggataa     1140

agatggaaaa ccactattgc cagagcctga agaaaaaccc aagcctcgga gtgaatcaga     1200

actcattgat gaactttcag aagattttga ccggtctgaa tgtaaagaga aaccatctaa     1260

gccaactgaa aagacagaag aatctaaggc cgctgctcca gctcctgtgt cggaggctgt     1320

gtgtcggacc tccatgtgta gtatacagtc agcaccccct gagccggcta ccttgaaggg     1380

cacagtgcca gatgatgctg tagaagcctt ggctgatagc ctggggaaaa aggaagcaga     1440

tccagaagat ggaaaacctg tgatggataa agtcaaggag aaggccaaag aagaagaccg     1500

tgaaaagctt ggtgaaaaag aagaaacaat tcctcctgat tatagattag aagaggtcaa     1560

ggataaagat ggaaagccac tcctgccaaa agagtctaag gaacagcttc cacccatgag     1620

tgaagacttc cttctggatg ctttgtctga ggacttctct ggtccacaaa atgcttcatc     1680

tcttaaattt gaagatgcta aacttgctgc tgccatctct gaagtggttt cccaaacccc     1740

agcttcaacg acccaagctg gagccccacc ccgtgatacc tcgcagagtg acaaagacct     1800

cgatgatgcc ttggataaac tctctgacag tctaggacaa aggcagcctg acccagatga     1860

gaacaaacca atggaagata aagtaaagga aaaagctaaa gctgaacata gagacaagct     1920

tggagaaaga gatgacacta tcccacctga atacagacat ctcctggatg ataatggaca     1980

ggacaaacca gtgaagccac ctacaaagaa atcagaggat tcaaagaaac ctgcagatga     2040

ccaagacccc attgatgctc tctcaggaga tctggacagc tgtccctcca ctacagaaac     2100

ctcacagaac acagcaaagg ataagtgcaa gaaggctgct tccagctcca aagcacctaa     2160

gaatggaggt aaagcgaagg attcagcaaa gacaacagag gaaacttcca agccaaaaga     2220

tgactaaaga aatacaagtt aaggtatctg gtatctgcat gtaaaatctt cagctggtgg     2280

atggtgactt ttgaagaaca aaaggctttg gcaacagaaa acaattgttc tgggtgattt     2340

ctagaatggt ttttgttgag tctctgaaca tcctaaatat tggtttgtta ttcttttcca     2400

gaaagaaaat gaatttgact ggttcacctg tgtactgagt attgataaac tttgaatttt     2460

tttaattgcc ttcaattggg agagaaagct ttatatttgt aagaaatata tttgataaag     2520

tttcttaaag caacaccaaa aaaacaaaag aaaagctaag tgaatttttg cacattctac     2580

acacagtgcc tgtaaatctc atttgtattt tcagtttgcc cttaattttt tttgttagtg     2640

tttagaaaac aatgttttaa acattcttca gtgttctgat ttcttattac cccctttcct     2700

cttgggcttt tgaactgtat ttgatgttgc tttgggataa tgtttataag tcaaacataa     2760

gatattgtac attgggcaca tatctcctct tgggctgcta ataataaatt aataacaggt     2820

aacctggaca aaccaggaag caccaaaccc cttttcagtt tgaactcttc tttgccaggt     2880

gtgaggactt ctgcatctta cagtcagcac agaacacact gagacttgaa tcaagtcagc     2940

aacagagcaa aataaaggtt agataagtcc ttgtgtagca aatttcgagc ataagaaata     3000

aaatctaatt aattcttagg gtactcatct gacttgaact ctgttggttt actgtgttag     3060

taaactgtgc tttctattat ctatacataa aacctgagca gcaactgtgt ctttagagct     3120

attgccacat tagcctttgc actgtatagc gtctggcttt atggaactta agtttaccaa     3180

atataaaaag aaacttctgc ttttaaaaaa attatatata tatattaaat ttgaaacctg     3240

catttctccc acagcaatgt aagaagtagg ctctgatgtc ctaccacttt gaatggtttt     3300

ctaatatctt aatgaatagt tcctgaacat tgcactgata tcatcgatta gaattttgat     3360

atttaatttc atctttattt cctggtagag aatgcaggaa aagatgtcag gtacataaca     3420

taaaacagat tgggaattta ttgtttccaa agggcatggc cttccttagc atcagtttga     3480

agcttttgtt atgacttagc tgacttgtgg cagcggggca agcaaaaaca ataacactgc     3540

ttataaatgg caccacatct tgttaacctc ccccccaaat actctctgaa agtcatgcac     3600

atacctatgg gattttacac accaccagct taaaatgcta tgtctctatc catcagaaat     3660

agtcattatt ctatttttaa ggcagcaaca agaaaagaaa aaacactttt cctgagggat     3720

ttctaaccat gtatctaatc ctcccatttg ggcagtatag gtgtttgctt ttttgttttc     3780

tttttttaag aaaaaccttg aaacctttga cactgacaga tgtgtttgca aggatacggc     3840

ttcagtatta ctaatttcca tgtgtatctg gaagtatttt taaatggcat accaaaatcc     3900

agaagtttaa agatgcctat aaaagtaaac aacatttatt taaaaagaac tctgaatatg     3960

ccttcttttt taattagaaa tatcttcgag acttgggtgt ttgttaataa ctaataactg     4020

gagtaagcta caggatctaa agcagccctt tttacagtct agttaggaga gagaaaataa     4080

ttgcaaatat ccacttagag gcaaagaaca attttttatt atcaaaaagg tttctgcaca     4140

ttgttgtggc aatattgtat ctgtttagaa aatgggcttt tccaaaagca aacaaagata     4200

ggttcctcag gtgaccaaaa ctgaaaatca atatttccat gtttcattaa tcaaggcata     4260

aaatacaatt aaagcaaaat attttacatt aaaaaaaaaa aaaa                      4304


<210>  708
<211>  4296
<212>  DNA
<213>  homo sapiens

<400>  708
agatgccgcc tggcaccaag cgcagccgcc gctgccgcac tttccacttg tattgatcac       60

ctctcagccc cgcgcagccg gctcgcccga gcggaccgcg gccagcgcgc cagcccttgg      120

cagccccgga gcagtcgggc tccgggagga aactccttgg gagcgccctg tccggggtgc      180

cctctgcgct ctgcagtgtc tttctttctg cctgggagga ggaggaggag gaggaagagg      240

aggaggagga ggaggaggag gaggaagagg aggaggagga ggaggacgtc tggtcccggc      300

tgggaggtgg agcagcggca gcagcagcag ccgccgccgc cgccgccgct gccgccgccg      360

ccggaaaggg agaggcagga gagcccgaga cttggaaacc ccaaagtgtc cgcgaccctg      420

cacggcaggc tcccttccag cttcatgggc aaagtgtgga aacagcagat gtaccctcag      480

tacgccacct actattaccc ccagtatctg caagccaagc agtctctggt cccagcccac      540

cccatggccc ctcccagtcc cagcaccacc agcagtaata acaacagtag cagcagtagc      600

aactcaggat gggatcagct cagcaaaacg aacctctata tccgaggact gcctccccac      660

accaccgacc aggacctggt gaagctctgt caaccatatg ggaaaatagt ctccacaaag      720

gcaattttgg ataagacaac gaacaaatgc aaaggttatg gttttgtcga ctttgacagc      780

cctgcagcag ctcaaaaagc tgtgtctgcc ctgaaggcca gtggggttca agctcaaatg      840

gcaaagcaac aggaacaaga tcctaccaac ctctacattt ctaatttgcc actctccatg      900

gatgagcaag aactagaaaa tatgctcaaa ccatttggac aagttatttc tacaaggata      960

ctacgtgatt ccagtggtac aagtcgtggt gttggctttg ctaggatgga atcaacagaa     1020

aaatgtgaag ctgttattgg tcattttaat ggaaaattta ttaagacacc accaggagtt     1080

tctgccccca cagaaccttt attgtgtaag tttgctgatg gaggacagaa aaagagacag     1140

aacccaaaca aatacatccc taatggaaga ccatggcata gagaaggaga ggctggaatg     1200

acacttactt acgacccaac tacagctgct atacagaacg gattttatcc ttcaccatac     1260

agtattgcta caaaccgaat gatcactcaa acttctatta caccctatat tgcatctcct     1320

gtatctgcct accaggtgca aagtccttcg tggatgcaac ctcaaccata tattctacag     1380

caccctggtg ccgtgttaac tccctcaatg gagcacacca tgtcactaca gcccgcatca     1440

atgatcagcc ctctggccca gcagatgagt catctgtcac taggcagcac cggaacatac     1500

atgcctgcaa cgtcagctat gcaaggagcc tacttgccac agtatgcaca tatgcagacg     1560

acagcggttc ctgttgagga ggcaagtggt caacagcagg tggctgtcga gacgtctaat     1620

gaccattctc catatacctt tcaacctaat aagtaactgt gagatgtaca gaaaggtgtt     1680

cttacatgaa gaagggtgtg aaggctgaac aatcatggat ttttctgatc aattgtgctt     1740

taggaaatta ttgacagttt tgcacaggtt cttgaaaacg ttatttataa tgaaatcaac     1800

taaaactatt tttgctataa gttctataag gtgcataaaa cccttaaatt catctagtag     1860

ctgttccccc gaacaggttt attttagtaa aaaaaaaaaa acaaaaaaca aaaacaaaag     1920

atttttatca aatgttatga tgcaaaaaaa gaaaaagaaa aaaaaaaaga aaagaaaact     1980

tcaattttct gggtatgcac aaagaccatg aagacttatc caagtgcatg accggatttt     2040

tgtggttttg ttcattttgt gtttaatttg tgtttttttt ttccagctgt atgaaatggg     2100

ctttctgaag tttaaatagt ccgacttcac ccatggtgtt ctgtgcttgc agtgcgagtg     2160

ttgctgtaat tcagtgttgc cgtcagtgtc tcttttctta gctttctgtc tttctttcaa     2220

cgtagtgtga agtgtcttat ccttttctat gaattccaat ttgccttaac tcttttgatg     2280

ctgtagctgt ttcagtaaaa gttagttcaa actaatgatg tagaatgctt tgaccaaatg     2340

agctggtcta ttatgccttg taaaacagca gcatagggct tttaaaaggt agtcaataaa     2400

agttgctgaa attttggctt ttttaaatat gtagtaggtg tttttaatga tttttcacat     2460

aatgtgtaag gtagtgaaat gcaagaaggg aaaaatgttt tgtgtgaaac acattttctg     2520

actggggaac ttttattagg gtaaattgtt tgtaaggctg tacgccaaca gtttcctctg     2580

atagtttgac tgatttagga tatctgctgt atgatgcaat gtaaagtctt ttttgccttt     2640

tttcaggaaa aaaaaaaagc taacttgatg tactagattt agtgtaggta gtgttggggt     2700

tggggatggg ggtgggggag gggagtcact gaatgttttg tccttccttt atactaatga     2760

tagtgcttta gaatgagaat tatgcctgaa atctggcaaa ccgaaaaatg ttgctattgc     2820

aacaaagtgg caaaagctaa aagtaaggat ttatcttcaa acataagctg agataacgaa     2880

tagaagcaaa acgattggct actagctctc tctctctctc tctattaggt aaatttgaaa     2940

aataaaaatg acttggcact tttaaaggta acttcaccaa agaccgaaga gccagtaacc     3000

agtagctcca acttgtctca gcatcacatc ttctgtgctc tttatttttg ccggaccagt     3060

ttgcggttag gagaatgtgc cttttttgta cctttgcatt taggttttat aattttaatt     3120

gatgtatgga cacacacaaa caaaaaagca tgaaggaaga tttggatcca agcagtgcca     3180

cactttacat catcactaca agtgttcaag tgtaaagaaa accaattttg aaactatgaa     3240

attcctgatt cataaataca cagttatttc tactttagta catataagat aattcactgt     3300

tattaaagct cttttattaa ggcaattgca tatgttttaa aagcaatggt aaattaagtt     3360

gtcttccaaa actgtgtact tgtctggtca gctgtgtatg atcagttatc tacctcagag     3420

tctattttct tttgtgctgg gacaggttgc tggccctccc tgtttccaca gaccaaatcc     3480

tcctagctca ggagctaggg ctaagcagtt atttctttca agtatttttt agttcttaaa     3540

ttttatgctt gtatttgatg atagatgtca gtgacatttc atagtttcaa aagtccttgc     3600

tgctctgaga agtgtagatt ctagtgaaaa ttacatagtc ataagagaaa tgtgtttttg     3660

tttttgtttt tgtttcattt ttttaaagtt gtggtattat tggttctatg ctccctggaa     3720

tattactgct ttgtgaaagt ccagactgaa cgcagcaccc tctgtgtacc tagtacagtt     3780

ataaacctgg gtctctcact acttgatatt tttgcattag ttaagacaga aatttgatag     3840

ctcggttaga ggggagggga aatctgctgc tagaaatgtc tgaactaagt gccatactcg     3900

tctgggtaag atttgggaaa cataacctct gtacataaaa aaaaaaaaat cagttaaaca     3960

tcacatagta gacagccatt aaattataaa aaaattaatt tatgaagaaa gaccttttgt     4020

acagattgaa aaaaaaagat tttcatagag atatctatat gatcaagaga gttaattttt     4080

tatttttgtt ttactagtgc cacagacttg ccagtggtaa cttatttgtc cggttcaaga     4140

taactctgta gttttctttc ctaggacttg ttgttaaacg ccaaaagaca tttttgaact     4200

gtacatttga tcagattgtt agcttttctg ttttatttct tttgagaacc tttgaataaa     4260

aaacatctga aattttaaaa aaaaaaaaaa aaaaaa                               4296


<210>  709
<211>  3352
<212>  DNA
<213>  homo sapiens

<400>  709
accgcctccc aggccaggcg agcaggcggg tggctggggc gcctccacct cctcttccta       60

aagcggcgag gcgcagagga gcggcatcac tcgagcccag gtcccagcca ccaccactca      120

cagcgctcgg cgttcaggaa gaggagcagc agcggaggcg gctgcttcag cggcgggcgg      180

gcgccagaaa ggccccgatc gaaaagcctg ggagggccgc cgaactaccc ccggagggag      240

gagccagtcc gaacccaagg cgccaccgcc gcagaagcgg agcgaggcag cattcgcctc      300

catggcccac tcgccggtgg ctgtccaagt gcctgggatg cagaataaca tagctgatcc      360

agaagaactg ttcacaaaat tagagcgcat tgggaaaggc tcatttgggg aagttttcaa      420

aggaattgat aaccgtaccc agcaagtcgt tgctattaaa atcatagacc ttgaggaagc      480

cgaagatgaa atagaagaca ttcagcaaga aataactgtc ttgagtcaat gtgacagctc      540

atatgtaaca aaatactatg ggtcatattt aaaggggtct aaattatgga taataatgga      600

atacctgggc ggtggttcag cactggatct tcttcgagct ggtccatttg atgagttcca      660

gattgctacc atgctaaagg aaattttaaa aggtctggac tatctgcatt cagaaaagaa      720

aattcaccga gacataaaag ctgccaatgt cttgctctca gaacaaggag atgttaaact      780

tgctgatttt ggagttgctg gtcagctgac agatacacag attaaaagaa atacctttgt      840

gggaactcca ttttggatgg ctcctgaagt tattcaacag tcagcttatg actcaaaagc      900

tgacatttgg tcattgggaa ttactgctat tgaactagcc aagggagagc cacctaactc      960

cgatatgcat ccaatgagag ttctgtttct tattcccaaa aacaatcctc caactcttgt     1020

tggagacttt actaagtctt ttaaggagtt tattgatgct tgcctgaaca aagatccatc     1080

atttcgtcct acagcaaaag aacttctgaa acacaaattc attgtaaaaa attcaaagaa     1140

gacttcttat ctgactgaac tgatagatcg ttttaagaga tggaaggcag aaggacacag     1200

tgatgatgaa tctgattccg agggctctga ttcggaatct accagcaggg aaaacaatac     1260

tcatcctgaa tggagcttta ccaccgtacg aaagaagcct gatccaaaga aagtacagaa     1320

tggggcagag caagatcttg tgcaaaccct gagttgtttg tctatgataa tcacacctgc     1380

atttgctgaa cttaaacagc aggacgagaa taacgctagc aggaatcagg cgattgaaga     1440

actcgagaaa agtattgctg tggctgaagc cgcctgtccc ggcatcacag ataaaatggt     1500

gaagaaacta attgaaaaat ttcaaaagtg ttcagcagac gaatccccct aagaaactta     1560

ttattggctt ctgtttcata tggacccaga gagccccacc aaacctacgt caagattaac     1620

aatgcttaac ccatgagctc catgtgcctt ttggatcttt gcaacactga agatttggaa     1680

gaagctatta aactattttg tgatggcgtt tatcatttta tattttgaaa ggattatttt     1740

gtaaggaata acttttaata ctatagtttc acctgtattc tagtaaatgt tgagacaccg     1800

ttttgctttt aagtatccct atttcttaag ttacgaggat gaataccttt cacattttga     1860

tctttagttg actctacagt catgaaacat acaggtcttt caaagtcatt ctcaatattc     1920

agcttttgta aattatcaag cttcaaaaag cttttttttt taaaaaaaaa catgcatatt     1980

ctaaaaatga ctattggtgg ggaggtgtaa ataagtcata ccttcttaaa acagaaaatt     2040

taagtaaagt cttttaaatg aaacctgtaa aagtattgac tcttctacca agttggtatg     2100

atattccagg cagctcaatg attatcacat ttgagaccct gtgtttgaag catttacagg     2160

caatgtacag caacagaggt acctcttggt gtatagtatt tacattctct tttaggtaga     2220

agaggcaatt ttacccttat ttcacatggt tagaaattta aagcaagatc atttacccaa     2280

ggataggtgt ttggtaatgt tgaaggagtt agtctggctt catgttttac atcttcaact     2340

aaaatcccat actatctgct tggatttgga gagccaaaaa ataaagctga ttgtcatgtg     2400

attaaatatc tgatcaacag gtatgaatat aacttaaatc agcatatttt tgccatggta     2460

ataaattgtc ctataaacta tttatatatt tttgttcttc ataattatca ctaataagca     2520

tcagtttgtt gtttttaaaa ggatatttaa gtgagcattt tctagttcat atgaaaataa     2580

ccatagtaca ggatgatttc tgtccacaca aaggttaaat tagattgcac agttaatttt     2640

cacttatatt tatggtacta ttatgtgggt gatgcctttt tcttttaagc ccagtacata     2700

tattatgcct gcctaagttc tgaactgggg ctgtatttca gtagttgtag aattattgat     2760

atttagtttt gatagctaat gtttaattgt ttggatctgc acagtttggt ttttgcacaa     2820

aagtcattta aaaaaatctg agtaattgtc aaatattaaa agaaagatat tcttcctgta     2880

aggaatacag tttttagtca aagtggccat tacatcctct ttttaattta cataatacag     2940

atacttgaga aagttgttgt ggtgttgtat gccaagaaaa ttctttttat tggtgcctat     3000

attgtaacaa ttatttttaa tgcattgtat tttgaagtaa cggttcagtt aaatttttca     3060

cctgctgtgt aactgaaaca caattacagt ttataatcat ctgtagaagt ctggagataa     3120

ttttgcaact catgttatgg gttaaatgaa tatttttgta aaagtaaaag caacaaattt     3180

ataaattgat tatttgaaac tttacaacac aattgcatcc caaatacaaa ttgtattgct     3240

tattcattat agctattcgt cctgtaatct gtttctaggt gaagcatact ccagtgtttt     3300

aggggttttg aaaataaata tttaaatttc acagtcaaaa aaaaaaaaaa aa             3352


<210>  710
<211>  1409
<212>  DNA
<213>  homo sapiens

<400>  710
gctgcccgaa ggacctgttg tgccgggtcc ggaaagcgtg tttcgctccc tttcccttga       60

gggagtgggg agggaatgtg actcttttcg cccagcgccg tggactcgcg gcttgtggct      120

cccaagttag ggagtgagag gatcgcccgc cgagggggtg gctccgcagc ccggctgcgc      180

gagacgcttc ccgctcgggg acccgccttc cgaggccagg tgaacgttac cggccccctg      240

acctccagca gatccacacg tttgttggag actgaaccgt tgcaaggaac agacgaagat      300

gcagtagcca gtgctgactt ctctagcatg ctctctgagg aggaaaagga agagttaaaa      360

gcagagttag ttcagctaga agacgaaatt acaacactac gacaagtttt gtcagcgaaa      420

gaaaggcatc tagttgagat aaaacaaaaa ctcggcatga acctgatgaa tgaattaaaa      480

cagaacttca gcaaaagctg gcatgacatg cagactacca ctgcctacaa gaaaacacat      540

gaaaccctga gtcacgcagg gcaaaaggca actgcagctt tcagcaacgt tggaacggcc      600

atcagcaaga agttcggaga catgagttac tccattcgcc attccataag tatgcctgct      660

atgaggaatt ctcctacttt caaatcattt gaggagaggg ttgagacaac tgtcacaagc      720

ctcaagacga aagtaggcgg tacgaaccct aatggaggca gttttgagga ggtcctcagc      780

tccacggccc atgccagtgc ccagagcttg gcaggaggct cccggcggac caaggaggag      840

gagctgcagt gctaagtcca gccagcgtgc agctgcatcc agaaaccggc cactacccag      900

cccatctctg cctgtgctta tccagataag aagaccaaaa tcccgctggg aaaaacccag      960

gccttgacat tgttattcaa atggcccctc cagaaagttt aatgatttcc atttgtattt     1020

gtgttgatga tggaccactt gaccatcaca tttcagtatt catagatgac tgtcacattt     1080

taaaatgttc ccacttgagc aggtacacaa ctggtcataa ttcctgtctg tgtaattcga     1140

tgtatatttt tccaaacatg tagctattgt ttgctttgat ttttgcttgg cctcctttat     1200

gatgtgcatg tccttgaagg ctgaatgaac agtccctttc agttcagcag atcaacagga     1260

tggagctctt catgactgtc tccagcaata ggatgattta ctataaattt catccaacta     1320

cttgtgatct ctctcaccta catcaattat gtatgttaat ttcagcaatt aaaagaattg     1380

attttaatga caaaaaaaaa aaaaaaaaa                                       1409


<210>  711
<211>  2397
<212>  DNA
<213>  homo sapiens

<400>  711
gagggaggag gaggagtggg gaccgggcgg ggggtggagg aagaggcctc gcgcagagga       60

gggagcaatt gaatttcaaa cacaaacaac tgcacgagcg cgcacccacc gcgccggagc      120

cttgccccga tccgcgcccg ccccgtccgt gcggcgcgcg ggcggagacg ccgtggccgc      180

gccggagctc gggccggggg ccaccatcga ggcgggggcc gcgcgagggc cggagcggag      240

cggcgccgcc accgccgcac gcgcaaactt gggctcgcgc ttcccggccc ggcgcggagc      300

ccggggcgcc cggagccccg ccatgtcgcg atccaaccgg cagaaggagt acaaatgcgg      360

ggacctggtg ttcgccaaga tgaagggcta cccacactgg ccggcccgga ttgacgagat      420

gcctgaggct gccgtgaaat caacagccaa caaataccaa gtcttttttt tcgggaccca      480

cgagacggca ttcctgggcc ccaaagacct cttcccttac gaggaatcca aggagaagtt      540

tggcaagccc aacaagagga aagggttcag cgaggggctg tgggagatcg agaacaaccc      600

tactgtcaag gcttccggct atcagtcctc ccagaaaaag agctgtgtgg aagagcctga      660

accagagccc gaagctgcag agggtgacgg tgataagaag gggaatgcag agggcagcag      720

cgacgaggaa gggaagctgg tcattgatga gccagccaag gagaagaacg agaaaggagc      780

gttgaagagg agagcagggg acttgctgga ggactctcct aaacgtccca aggaggcaga      840

aaaccctgaa ggagaggaga aggaggcagc caccttggag gttgagaggc cccttcctat      900

ggaggtggaa aagaatagca ccccctctga gcccggctct ggccgggggc ctccccaaga      960

ggaagaagaa gaggaggatg aagaggaaga ggctaccaag gaagatgctg aggccccagg     1020

catcagagat catgagagcc tgtagccacc aatgtttcaa gaggagcccc caccctgttc     1080

ctgctgctgt ctgggtgcta ctggggaaac tggccatggc ctgcaaactg ggaacccctt     1140

tcccacccca acctgctctc ctcttctact cacttttccc actccaagcc cagcccatgg     1200

agattgacct ggatggggca ggccacctgg ctctcacctc taggtcccca tactcctatg     1260

atctgagtca gagccatgtc ttctccctgg aatgagttga ggccactgtg ttccttccgc     1320

ttggagctat tttccaggct tctgctgggg cctgggacaa ctgctcccac ctcctgacac     1380

ccttctccca ctctcctagg cattctggac ctctgggttg ggatcagggg taggaatgga     1440

aaggatggag catcaacagc agggtgggct tgtggggcct gggaggggca atcctcaaat     1500

gcggggtggg ggcagcacag gagggcggcc tccttctgag ctcctgtccc ctgctacacc     1560

tattatccca gctgcctaga ttcagggaaa gtgggacagc ttgtagggga ggggctcctt     1620

tccataaatc cttgatgatt gacaacaccc atttttcctt ttgccgaccc caagagtttt     1680

gggagttgta gttaatcatc aagagaattt ggggcttcca agttgttcgg gccaaggacc     1740

tgagacctga agggttgact ttacccattt gggtgggagt gttgagcatc tgtccccctt     1800

tagatctctg aagccacaaa taggatgctt gggaagactc ctagctgtcc tttttcctct     1860

ccacacagtg ctcaaggcca gcttatagtc atatatatca cccagacata aaggaaaaga     1920

cacatttttt aggaaatgtt tttaataaaa gaaaattaca aaaaaaaatt ttaaagaccc     1980

ctaacccttt gtgtgctctc cattctgctc cttccccatc gttgccccca tttctgaggt     2040

gcactgggag gctccccttc tatttggggc ttgatgactt tctttttgta gctggggctt     2100

tgatgttcct tccagtgtca tttctcatcc acataccctg acctggcccc ctcagtgttg     2160

tcaccagatc tgatttgtaa cccactgaga ggacagagag aaataagtgc cctctcccac     2220

cctcttccta ctggtctctc tatgcctctc tacagtctcg tctcttttac cctggcccct     2280

ctcccttggg ctctgatgaa aaattgctga ctgtagcttt ggaagtttag ctctgagaac     2340

cgtagatgat ttcagttcta ggaaaataaa acccgttgat tactataaaa aaaaaaa        2397


<210>  712
<211>  2208
<212>  DNA
<213>  homo sapiens

<400>  712
agaactgagc tcatctttgc ggggttagct agccgttgag tccaagtctc cttggcaaga       60

cagtagctta gagaaacgag atcgaatgca cccggaaggt ggccaatttg tgcctcaact      120

ccttggccat ctcctggcta ccaaactcaa gcgtttcctc cttagcaaag gcggacgtag      180

ggctcaaatc cccgacgttt ccagggccac cccccatacg attgacgaga tgcctgaggc      240

tgccgtgaaa tcaacagcca acaaatacca agtctttttt ttcgggaccc acgagacggc      300

attcctgggc cccaaagacc tcttccctta cgaggaatcc aaggagaagt ttggcaagcc      360

caacaagagg aaagggttca gcgaggggct gtgggagatc gagaacaacc ctactgtcaa      420

ggcttccggc tatcagtcct cccagaaaaa gagctgtgtg gaagagcctg aaccagagcc      480

cgaagctgca gagggtgacg gtgataagaa ggggaatgca gagggcagca gcgacgagga      540

agggaagctg gtcattgatg agccagccaa ggagaagaac gagaaaggag cgttgaagag      600

gagagcaggg gacttgctgg aggactctcc taaacgtccc aaggaggcag aaaaccctga      660

aggagaggag aaggaggcag ccaccttgga ggttgagagg ccccttccta tggaggtgga      720

aaagaatagc accccctctg agcccggctc tggccggggg cctccccaag aggaagaaga      780

agaggaggat gaagaggaag aggctaccaa ggaagatgct gaggccccag gcatcagaga      840

tcatgagagc ctgtagccac caatgtttca agaggagccc ccaccctgtt cctgctgctg      900

tctgggtgct actggggaaa ctggccatgg cctgcaaact gggaacccct ttcccacccc      960

aacctgctct cctcttctac tcacttttcc cactccaagc ccagcccatg gagattgacc     1020

tggatggggc aggccacctg gctctcacct ctaggtcccc atactcctat gatctgagtc     1080

agagccatgt cttctccctg gaatgagttg aggccactgt gttccttccg cttggagcta     1140

ttttccaggc ttctgctggg gcctgggaca actgctccca cctcctgaca cccttctccc     1200

actctcctag gcattctgga cctctgggtt gggatcaggg gtaggaatgg aaaggatgga     1260

gcatcaacag cagggtgggc ttgtggggcc tgggaggggc aatcctcaaa tgcggggtgg     1320

gggcagcaca ggagggcggc ctccttctga gctcctgtcc cctgctacac ctattatccc     1380

agctgcctag attcagggaa agtgggacag cttgtagggg aggggctcct ttccataaat     1440

ccttgatgat tgacaacacc catttttcct tttgccgacc ccaagagttt tgggagttgt     1500

agttaatcat caagagaatt tggggcttcc aagttgttcg ggccaaggac ctgagacctg     1560

aagggttgac tttacccatt tgggtgggag tgttgagcat ctgtccccct ttagatctct     1620

gaagccacaa ataggatgct tgggaagact cctagctgtc ctttttcctc tccacacagt     1680

gctcaaggcc agcttatagt catatatatc acccagacat aaaggaaaag acacattttt     1740

taggaaatgt ttttaataaa agaaaattac aaaaaaaaat tttaaagacc cctaaccctt     1800

tgtgtgctct ccattctgct ccttccccat cgttgccccc atttctgagg tgcactggga     1860

ggctcccctt ctatttgggg cttgatgact ttctttttgt agctggggct ttgatgttcc     1920

ttccagtgtc atttctcatc cacataccct gacctggccc cctcagtgtt gtcaccagat     1980

ctgatttgta acccactgag aggacagaga gaaataagtg ccctctccca ccctcttcct     2040

actggtctct ctatgcctct ctacagtctc gtctctttta ccctggcccc tctcccttgg     2100

gctctgatga aaaattgctg actgtagctt tggaagttta gctctgagaa ccgtagatga     2160

tttcagttct aggaaaataa aacccgttga ttactataaa aaaaaaaa                  2208


<210>  713
<211>  2183
<212>  DNA
<213>  homo sapiens

<400>  713
tacggtaagc acggcgaggt ccagagagga ccccagtgcg cggagcggca cggcgcccac       60

tcctctcgcc ctcggcgcct agcacgctgc caagaaccgc gggtgcccag taaatatttg      120

tggattgaga tggagcagag ggcaggcgga aaccgtgtac agacgtccac acttaactgc      180

gctggggccg cggtgattga cgagatgcct gaggctgccg tgaaatcaac agccaacaaa      240

taccaagtct tttttttcgg gacccacgag acggcattcc tgggccccaa agacctcttc      300

ccttacgagg aatccaagga gaagtttggc aagcccaaca agaggaaagg gttcagcgag      360

gggctgtggg agatcgagaa caaccctact gtcaaggctt ccggctatca gtcctcccag      420

aaaaagagct gtgtggaaga gcctgaacca gagcccgaag ctgcagaggg tgacggtgat      480

aagaagggga atgcagaggg cagcagcgac gaggaaggga agctggtcat tgatgagcca      540

gccaaggaga agaacgagaa aggagcgttg aagaggagag caggggactt gctggaggac      600

tctcctaaac gtcccaagga ggcagaaaac cctgaaggag aggagaagga ggcagccacc      660

ttggaggttg agaggcccct tcctatggag gtggaaaaga atagcacccc ctctgagccc      720

ggctctggcc gggggcctcc ccaagaggaa gaagaagagg aggatgaaga ggaagaggct      780

accaaggaag atgctgaggc cccaggcatc agagatcatg agagcctgta gccaccaatg      840

tttcaagagg agcccccacc ctgttcctgc tgctgtctgg gtgctactgg ggaaactggc      900

catggcctgc aaactgggaa cccctttccc accccaacct gctctcctct tctactcact      960

tttcccactc caagcccagc ccatggagat tgacctggat ggggcaggcc acctggctct     1020

cacctctagg tccccatact cctatgatct gagtcagagc catgtcttct ccctggaatg     1080

agttgaggcc actgtgttcc ttccgcttgg agctattttc caggcttctg ctggggcctg     1140

ggacaactgc tcccacctcc tgacaccctt ctcccactct cctaggcatt ctggacctct     1200

gggttgggat caggggtagg aatggaaagg atggagcatc aacagcaggg tgggcttgtg     1260

gggcctggga ggggcaatcc tcaaatgcgg ggtgggggca gcacaggagg gcggcctcct     1320

tctgagctcc tgtcccctgc tacacctatt atcccagctg cctagattca gggaaagtgg     1380

gacagcttgt aggggagggg ctcctttcca taaatccttg atgattgaca acacccattt     1440

ttccttttgc cgaccccaag agttttggga gttgtagtta atcatcaaga gaatttgggg     1500

cttccaagtt gttcgggcca aggacctgag acctgaaggg ttgactttac ccatttgggt     1560

gggagtgttg agcatctgtc cccctttaga tctctgaagc cacaaatagg atgcttggga     1620

agactcctag ctgtcctttt tcctctccac acagtgctca aggccagctt atagtcatat     1680

atatcaccca gacataaagg aaaagacaca ttttttagga aatgttttta ataaaagaaa     1740

attacaaaaa aaaattttaa agacccctaa ccctttgtgt gctctccatt ctgctccttc     1800

cccatcgttg cccccatttc tgaggtgcac tgggaggctc cccttctatt tggggcttga     1860

tgactttctt tttgtagctg gggctttgat gttccttcca gtgtcatttc tcatccacat     1920

accctgacct ggccccctca gtgttgtcac cagatctgat ttgtaaccca ctgagaggac     1980

agagagaaat aagtgccctc tcccaccctc ttcctactgg tctctctatg cctctctaca     2040

gtctcgtctc ttttaccctg gcccctctcc cttgggctct gatgaaaaat tgctgactgt     2100

agctttggaa gtttagctct gagaaccgta gatgatttca gttctaggaa aataaaaccc     2160

gttgattact ataaaaaaaa aaa                                             2183


<210>  714
<211>  7856
<212>  DNA
<213>  homo sapiens

<400>  714
aatgcctcgc tgtcgccgcc gccggcaatt ccagactctg ctagggttag cagagcagcc       60

ggtaacgttg ctggaccggg acgcacgctc agctgaggag gacccccaaa gatttttatt      120

gttaggtata ttgaccaaag tttaacgaga agaactgtga tcagctggga ggattgctgc      180

aaggaatgga attagctcat agcttactgc tgaatgaaga agcatacaat caactaggtg      240

aagttcagaa ggcagagttt atttttgagt ggttgagata cttggagaag ctcttgttgg      300

caaccagcag gaatgatgta agggagaaac agaagactct tgttgaacag ctcctgtctt      360

tgttgaacag ctccccaggg cctcctaccc gcaaactgct tgctaagaat ctagccatac      420

tttatagtat tggagacaca ttctccgttc atgaagcaat cgataaatgt aatgatctta      480

ttcgtagcaa agatgattct ccaagttatc ttcccactaa gcttgctgct gtggtatgtt      540

tgggttcctt gtacaagaag ttgggtagaa tactgggtaa cacctttact gatacagtgg      600

ggaatattct taaagctatg aagagtgcag agtctcaagg ccgatatgag attatgctaa      660

gtctgcaaaa tatattgaat ggactaggag ctgccgctgc accttgtcac agggatgttt      720

ataaagctgc tagatcctgc ttgacagata gatccatggc tgttcgttgt gctgctgcaa      780

agtgtctcct tgaacttcag aatgaagcca tctttatgtg gagtacggac ctggacagtg      840

tggccacact gtgttttaag tcctttgaag gttccaatta tgatgtgcgg atttctgttt      900

caaagttact aggcataata ttagctaaag ctgtaatttc taaacatcca ggaacagcag      960

cctcacgtca aagcattcgc agagtatctt tggaggaagt tctggaatta ctaggaacag     1020

ggtttctacg tgggagttca ggattccttc gagccagtgg agatatgctg aaaggaacca     1080

gttcagtcag tagggatgtt cgagttggag ttactcaggc ttatgtggta tttgtttcaa     1140

cactaggagg agcttggcta gagaaaaatt ttgctgcctt tttttctcat atcctaagcc     1200

ttgcgtcacc gtcacaccct aaagccaccc aaactcagat cgatgccgtc tgctgtcgcc     1260

gttgtgtttc atttattctt cgaactacta taggtggtct tcttggagaa aaggctcagc     1320

ttgctgctgt aaaggatatt tgccaggcca tctggaagct aaagaaagtt atggatgccg     1380

taatgagtga tggtaatttg gaaacccggc ttggttccac agatgtagcc gctagccaac     1440

atatgctggt ttgtgcttta caagaacttg gaaatctcat acacaatctt ggcaccacag     1500

cggcaccttt gctacaggat tcaagtacag gtctccttga cagtatcttg tcagttattc     1560

ttcatcctag catttctgtt cgactagcag cagcttggtg tttacactgc attgccgtgg     1620

cattaccctc ctacctaaca ccactcttgg atcgttgcct tgaacggctt actggacata     1680

agtcttcacc tgaagcagtg actggcttca gttttgctgt agcagctttg ttgggagcag     1740

taaaacattg tcctttagga attcctcatg gaaaaggcaa gattattatg acattagcag     1800

aggatttgct gtgttctgct gctcaaaaca gtcgcctttc agctcagcgc acacaagctg     1860

gatggttgct gatttctgct ctgatgacat taggtcctgc agttgttagc catcaccttg     1920

ctcgagttct gctgttgtgg aagtgtgtct ttccagcatc tcctaaagat ctagaaacag     1980

aaaagagccg aggagattcg tttacatggc aggtgaccct ggaaggacga gctggtgcac     2040

tgtgtgctat caagagcttt gtttcccact gtggtgatct tcttactgag gaagtaactc     2100

agcgtcttct tccaccactt ccttgtgctg tggatttgct aactcagctt tcttcaatac     2160

taaaaatgta tggaagtcct ttgaaaacac cgtcagtggt ttatagacaa agactttatg     2220

aactgttgat tttattacct cctgagacct atgaaggaaa cctctgtgct atcctcagag     2280

agctggctgc tgacttgact gcccctgata ttcaggtggc agcatctaca tttttacttc     2340

cacccctctg tcatcaggat gatcttttga tactaagtcc tttcctacaa gagactgacc     2400

atagatttat tgaagaacag ctcctgcttg gtaatggtgt tgcttgcgga agtcttgaat     2460

atgaccctta ttcgatttat gagaaagatg tagagggaga ttcagtgcct aagcccttac     2520

ctccagcact atcagttatt agttctgcat ccaagctctt tggggttgta tgcgctcatg     2580

tgggagaaac tcaaaggctt cttatattgg aacagctttt ggacagtata aagcacacaa     2640

aaggagctcg tcagcaagtg gttcagttac atgttgtttc ttcagtttct agtttcttga     2700

agtacgtggc tggctccaag ggatgtttag gtccagaaga aatgaaaaga tttgccttaa     2760

cattagttat gggagcccta gaaagcccca accccttgct gagatgtgca gctgcagagt     2820

catgggctag attagcccaa gtggtagatg atggagcttt tactgctgga ttagctcaag     2880

ttagctttga caaattgaaa tcagcaaggg atgtggttac cagaacagga cactcattgg     2940

ccttggggtc cctacatagg tatttaggag gaataagttc ttctcaacac ctaaattctt     3000

gtattggaat cctttatact ttggcgcagg acagcacttc tcctgatgtg cagacctggg     3060

cattacattc tctatcattg atcattgatt ctgctggccc actctattat gtgcatgtgg     3120

aacctaccct ttctcttatt ataatgttgt tgttaaatgt gcctcctact catgctgaag     3180

ttcaccaaag ccttggtcgc tgtttgaatg cccttattac cacgttaggt ccagagctac     3240

aaggtaacag tacttcaatt tctaccttaa ggacttcctg tctactgggt tgtgcagtaa     3300

tgcaagataa cccagactgc cttgttcaag ctcaggccat ctcttgcctt cagcagcttc     3360

atatgtttgc tccacgacat gtcaacttgt ctagcctggt tagctgcctc tgtgtgaatc     3420

tttgtagccc ctacttgtta ctgagaagag cagtactggc ttgcttacgt cagcttgtac     3480

aaagagaagc agctgaagtt tcagaacatg ctgttatgct tgctaaggat agcagagaag     3540

agttgactcc agatgctaac atcagagaag ttggccttga gggggcattg ttgatcttac     3600

tagacaagga gacagatgag agattatgcc atgatatcaa agagacttta aattatatgc     3660

ttacatctat ggcagtggaa aaactctccc tgtggttaaa gctttgtaaa gatgtacttg     3720

ctgcatcagc tgattttaca gctgtaactt gtgtggatac aatgcaagaa gaagaaggag     3780

ataaagggga tgatgcctca gtcctgacca ccagacgtga tgaaaaatcc catcctttta     3840

ccaatccccg atgggctact agagtctttg ctgctgaatg tgtctgtagg ataattaacc     3900

aatgtgagaa tgctaacagt gcacattttg acattgcttt agcacaagaa atgaaaaaaa     3960

gagattcaag aaatgacttt ttggtactgc atcttgctga cttaattcgc atggctttta     4020

tggctgccac agatcacagt gaccagctcc gtctttctgg ccttgaaatg ctgttagttg     4080

ttattcggcg atttgcaact gttccagaac cagagtttcc aggtcatgtg attctggaac     4140

agtatcaagc caatgtagga gcagcgctta gaccagcctt cacttcagag acaccacctg     4200

atgtcactgc caaagcatgt caggtttgca gtgcctggat agcaagtgga gttgtaagtg     4260

accttaatga tctccgaaga gttcatcagt tgcttgtttc atcgttaact aaaatacagg     4320

ctggaaaaga agctctaagt cacttatata atgaaagtgc ttctaccatg gagatcttag     4380

ctgtgcttaa agcctgggca gaggtctaca taattgctgt gcaaagacat aaaaaccaca     4440

gacaaccttt gaagactacc acctgtttag aagacggtat cagaaatgga tcatgttcat     4500

cagatggact gcttgactta gtctatgcag atcttggcac actaagcaga ctctggcttg     4560

ctgcacttca ggattttgct cttttaactt tgccttcaga atttgcctcc caacttcctg     4620

ctgaaggtgg tgctttctac acagcagaga ctagtgaaaa tgcaaaattg cattattaca     4680

actcctgggc acttatcctc catgctacag cattgtggct tacaagcacg ggttttgttg     4740

ttgctgaccc agatgaagga gcatctaatc tctccaggcc tgtaacacca acttccatgt     4800

gtcagggttc atcatctggg gctaccataa agtcccctga ggatgtctac actgatagat     4860

tccatcttat tttaggaatc agcgtggaat ttctatgttc cttacgttca gatgcaacca     4920

tggaaagcat aactgcttgt ttacatgcat tgcaagcact tctagatgta ccttggccca     4980

gatcaaaaat tggcagtgat caggacttgg gtatagaatt gctgaatgtt ctacatcgag     5040

taattttaac cagagaatca ccttccattc agttggcttc acttgaagtg gtaaggcaga     5100

ttatctgtgc tgctcaagaa catgtgaagg aaaaaagacg aagtgcagaa gttgatgatg     5160

gggctgctga aaaggaaact ctgccagagt ttggagaggg aaaggacacc ggaggacttg     5220

tgcctggaaa gtctttggtc tttgcaacac tggaattgtg tgtatgcatt ctagttagac     5280

agctcccaga attaaaccct aaattgacag gtagcccagg agtaaaagct acgaagccac     5340

agatactatt agaagatgga agtagattgg tttcagctgc attggttatc ctttccgaac     5400

ttcctgcagt gtgctctcct gaaggaagca tctcaattct ccctactata ttgtacctca     5460

caatcggggt cctcagagag actgctgtga agttacctgg gggccagtta tcttcgacag     5520

ttgcagcttc cctacaggct ctaaaaggaa tattatcttc tcccatggcc cgggcagaaa     5580

agagccgtac tgcttggact gaccttctcc gaagtgcctt aacaacaatt cttgactgtt     5640

gggatccagt tgatgaaaca caccaagaac ttgatgaagt cagtctactt actgctatca     5700

cagtgtttat tttgtctacc agtccagaag taactaccat cccatgcctt cagaagcgct     5760

gtattgataa atttaaagct actcttgaga taaaagatcc tgtggtacaa atcaagacct     5820

accagctcct acattccatc tttcagtatc caaatccagc tgtttcctac ccatacattt     5880

actctttagc atcctgtatc atggaaaaac tgcaggaaat agacaagaga aaacctgaaa     5940

acactgctga gcttgagatc ttccaagaag gcataaaggt cttagaaaca ctggttactg     6000

ttgctgaaga acaccatcgc gctcagctgg tggcctgtct tttgcccatc ctcatttcct     6060

tccttttgga tgaaaattct ctgggatcag caacttccat aatgagaaat ttacatgact     6120

ttgctctaca aaatctcatg caaattggac ctcagtattc atctgttttt aaaagtttag     6180

tggcttcttc tccagcccta aaagcccgcc ttgaggctgc tataaagggc aatcaggaaa     6240

gtgtcaaagt caagatacca acatctaaat atactaagag tcctggaaaa aactcaagca     6300

tccaattaaa gaccagtttc ctctgatttt ttttttggaa tagtaagcac cttaatataa     6360

taaatacttg atcattgcct ttggtgacaa aagggacatt gtagacacaa gtgcccttag     6420

aggtctagtt gattgtttta ccttaaatag ctgtgactct tcaaagtaac agcatactta     6480

acatttttgt gtgtgtgcgt ggggtttgtg ttttgttttg ttttgttttt ctatttaaaa     6540

agacaatgga gctaacttgc caggaatttt aagaaagtgc taaagaacta aacttactaa     6600

acaatccact gctttaaaaa tgaaatgaat ttcttctaac agtccataca tatgtggtat     6660

acttaatact gtgacagata taaatatgac tctagtgtaa attatctgca ctaatattgt     6720

atcccaattg ctgatttaaa attctgcttt ggcccggcac agtggctcat ccctgtaatt     6780

ccagcacttt ggaaggccaa ggcgggcgga tcacgaggtc gggagtttga gaccagcctg     6840

accaacatgg tgaaaccccg tctctactaa aaatacaaaa attagccggg tgtggtggca     6900

cacacctgta atcccagcta ctcaggaggc cgaggcagga aaatcgcttg aacctggcag     6960

gcagaggttg cagtgagcca agattgtgcc actgcactcc agcctgggcg acagagtgag     7020

actccatcta aaaaaaaaaa aaaaaaattc tgccttattc agtaattgta ttaaactttc     7080

tctgatttct ccaagaagat aaaatgattg gagagctatt taggaaacct ggtctaggat     7140

tatccagtat acaatagtac aaattactta cagccttaca gtgcaacata agatttggtg     7200

tctatatcat ggttttccac catcttttgg tttagtttat attgggttca gaaattgagt     7260

cttactcatt ttaaatagaa taagccattt ccactatttt tcaaatggat ttttctgttt     7320

acctctgttc ttaccaattt tgttcatttt catttgtggc aaacatttgt atcaatgagt     7380

tttaacctag gttcatatct acattgtatt tagatcaact atgggtttat ataaatgcca     7440

aatttagtac aacaaattta ggtcatcagg tgaatacaag tatttttttt aacaggaaac     7500

attttattat agaaaaaaga ttaatgataa agtcatattg gttgaaaaat attttttaac     7560

tgtgttcatg attgttgatt ctccttctac ttcagtgtta tactgtgtga atcaagcact     7620

gtgtcaaaac agagcatttc cctcttaaaa attacaaacc gaagtgatag aagcatgtca     7680

gaattgagaa gacattttga agcaagaaca atgtgatgta cctattttat tatgtttgta     7740

tataaatact attgtaaatt gttcagagtg aaaacatttg acaaactcta acactacaat     7800

cattttttct aaattacata aataaagcta attttcatta tcaaaaaaaa aaaaaa         7856


<210>  715
<211>  7856
<212>  DNA
<213>  homo sapiens

<400>  715
aatgcctcgc tgtcgccgcc gccggcaatt ccagactctg ctagggttag cagagcagcc       60

ggtaacgttg ctggaccggg acgcacgctc agctgaggag gacccccaaa gatttttatt      120

gttaggtata ttgaccaaag tttaacgaga agaactgtga tcagctggga ggattgctgc      180

aaggaatgga attagctcat agcttactgc tgaatgaaga agcatacaat caactaggtg      240

aagttcagaa ggcagagttt atttttgagt ggttgagata cttggagaag ctcttgttgg      300

caaccagcag gaatgatgta agggagaaac agaagactct tgttgaacag ctcctgtctt      360

tgttgaacag ctccccaggg cctcctaccc gcaaactgct tgctaagaat ctagccatac      420

tttatagtat tggagacaca ttctccgttc atgaagcaat cgataaatgt aatgatctta      480

ttcgtagcaa agatgattct ccaagttatc ttcccactaa gcttgctgct gtggtatgtt      540

tgggttcctt gtacaagaag ttgggtagaa tactgggtaa cacctttact gatacagtgg      600

ggaatattct taaagctatg aagagtgcag agtctcaagg ccgatatgag attatgctaa      660

gtctgcaaaa tatattgaat ggactaggag ctgccgctgc accttgtcac agggatgttt      720

ataaagctgc tagatcctgc ttgacagata gatccatggc tgttcgttgt gctgctgcaa      780

agtgtctcct tgaacttcag aatgaagcca tctttatgtg gagtacggac ctggacagtg      840

tggccacact gtgttttaag tcctttgaag gttccaatta tgatgtgcgg atttctgttt      900

caaagttact aggcataata ttagctaaag ctgtaatttc taaacatcca ggaacagcag      960

cctcacgtca aagcattcgc agagtatctt tggaggaagt tctggaatta ctaggaacag     1020

ggtttctacg tgggagttca ggattccttc gagccagtgg agatatgctg aaaggaacca     1080

gttcagtcag tagggatgtt cgagttggag ttactcaggc ttatgtggta tttgtttcaa     1140

cactaggagg agcttggcta gagaaaaatt ttgctgcctt tttttctcat atcctaagcc     1200

ttgcgtcacc gtcacaccct aaagccaccc aaactcagat cgatgccgtc tgctgtcgcc     1260

gttgtgtttc atttattctt cgaactacta taggtggtct tcttggagaa aaggctcagc     1320

ttgctgctgt aaaggatatt tgccaggcca tctggaagct aaagaaagtt atggatgccg     1380

taatgagtga tggtaatttg gaaacccggc ttggttccac agatgtagcc gctagccaac     1440

atatgctggt ttgtgcttta caagaacttg gaaatctcat acacaatctt ggcaccacag     1500

cggcaccttt gctacaggat tcaagtacag gtctccttga cagtatcttg tcagttattc     1560

ttcatcctag catttctgtt cgactagcag cagcttggtg tttacactgc attgccgtgg     1620

cattaccctc ctacctaaca ccactcttgg atcgttgcct tgaacggctt actggacata     1680

agtcttcacc tgaagcagtg actggcttca gttttgctgt agcagctttg ttgggagcag     1740

taaaacattg tcctttagga attcctcatg gaaaaggcaa gattattatg acattagcag     1800

aggatttgct gtgttctgct gctcaaaaca gtcgcctttc agctcagcgc acacaagctg     1860

gatggttgct gatttctgct ctgatgacat taggtcctgc agttgttagc catcaccttg     1920

ctcgagttct gctgttgtgg aagtgtgtct ttccagcatc tcctaaagat ctagaaacag     1980

aaaagagccg aggagattcg tttacatggc aggtgaccct ggaaggacga gctggtgcac     2040

tgtgtgctat caagagcttt gtttcccact gtggtgatct tcttactgag gaagtaactc     2100

agcgtcttct tccaccactt ccttgtgctg tggatttgct aactcagctt tcttcaatac     2160

taaaaatgta tggaagtcct ttgaaaacac cgtcagtggt ttatagacaa agactttatg     2220

aactgttgat tttattacct cctgagacct atgaaggaaa cctctgtgct atcctcagag     2280

agctggctgc tgacttgact gcccctgata ttcaggtggc agcatctaca tttttacttc     2340

cacccctctg tcatcaggat gatcttttga tactaagtcc tttcctacaa gagactgacc     2400

atagatttat tgaagaacag ctcctgcttg gtaatggtgt tgcttgcgga agtcttgaat     2460

atgaccctta ttcgatttat gagaaagatg tagagggaga ttcagtgcct aagcccttac     2520

ctccagcact atcagttatt agttctgcat ccaagctctt tggggttgta tgcgctcatg     2580

tgggagaaac tcaaaggctt cttatattgg aacagctttt ggacagtata aagcacacaa     2640

aaggagctcg tcagcaagtg gttcagttac atgttgtttc ttcagtttct agtttcttga     2700

agtacgtggc tggctccaag ggatgtttag gtccagaaga aatgaaaaga tttgccttaa     2760

cattagttat gggagcccta gaaagcccca accccttgct gagatgtgca gctgcagagt     2820

catgggctag attagcccaa gtggtagatg atggagcttt tactgctgga ttagctcaag     2880

ttagctttga caaattgaaa tcagcaaggg atgtggttac cagaacagga cactcattgg     2940

ccttggggtc cctacatagg tatttaggag gaataagttc ttctcaacac ctaaattctt     3000

gtattggaat cctttatact ttggcgcagg acagcacttc tcctgatgtg cagacctggg     3060

cattacattc tctatcattg atcattgatt ctgctggccc actctattat gtgcatgtgg     3120

aacctaccct ttctcttatt ataatgttgt tgttaaatgt gcctcctact catgctgaag     3180

ttcaccaaag ccttggtcgc tgtttgaatg cccttattac cacgttaggt ccagagctac     3240

aaggtaacag tacttcaatt tctaccttaa ggacttcctg tctactgggt tgtgcagtaa     3300

tgcaagataa cccagactgc cttgttcaag ctcaggccat ctcttgcctt cagcagcttc     3360

atatgtttgc tccacgacat gtcaacttgt ctagcctggt tagctgcctc tgtgtgaatc     3420

tttgtagccc ctacttgtta ctgagaagag cagtactggc ttgcttacgt cagcttgtac     3480

aaagagaagc agctgaagtt tcagaacatg ctgttatgct tgctaaggat agcagagaag     3540

agttgactcc agatgctaac atcagagaag ttggccttga gggggcattg ttgatcttac     3600

tagacaagga gacagatgag agattatgcc atgatatcaa agagacttta aattatatgc     3660

ttacatctat ggcagtggaa aaactctccc tgtggttaaa gctttgtaaa gatgtacttg     3720

ctgcatcagc tgattttaca gctgtaactt gtgtggatac aatgcaagaa gaagaaggag     3780

ataaagggga tgatgcctca gtcctgacca ccagacgtga tgaaaaatcc catcctttta     3840

ccaatccccg atgggctact agagtctttg ctgctgaatg tgtctgtagg ataattaacc     3900

aatgtgagaa tgctaacagt gcacattttg acattgcttt agcacaagaa atgaaaaaaa     3960

gagattcaag aaatgacttt ttggtactgc atcttgctga cttaattcgc atggctttta     4020

tggctgccac agatcacagt gaccagctcc gtctttctgg ccttgaaatg ctgttagttg     4080

ttattcggcg atttgcaact gttccagaac cagagtttcc aggtcatgtg attctggaac     4140

agtatcaagc caatgtagga gcagcgctta gaccagcctt cacttcagag acaccacctg     4200

atgtcactgc caaagcatgt caggtttgca gtgcctggat agcaagtgga gttgtaagtg     4260

accttaatga tctccgaaga gttcatcagt tgcttgtttc atcgttaact aaaatacagg     4320

ctggaaaaga agctctaagt cacttatata atgaaagtgc ttctaccatg gagatcttag     4380

ctgtgcttaa agcctgggca gaggtctaca taattgctgt gcaaagacat aaaaaccaca     4440

gacaaccttt gaagactacc acctgtttag aagacggtat cagaaatgga tcatgttcat     4500

cagatggact gcttgactta gtctatgcag atcttggcac actaagcaga ctctggcttg     4560

ctgcacttca ggattttgct cttttaactt tgccttcaga atttgcctcc caacttcctg     4620

ctgaaggtgg tgctttctac acagcagaga ctagtgaaaa tgcaaaattg cattattaca     4680

actcctgggc acttatcctc catgctacag cattgtggct tacaagcacg ggttttgttg     4740

ttgctgaccc agatgaagga gcatctaatc tctccaggcc tgtaacacca acttccatgt     4800

gtcagggttc atcatctggg gctaccataa agtcccctga ggatgtctac actgatagat     4860

tccatcttat tttaggaatc agcgtggaat ttctatgttc cttacgttca gatgcaacca     4920

tggaaagcat aactgcttgt ttacatgcat tgcaagcact tctagatgta ccttggccca     4980

gatcaaaaat tggcagtgat caggacttgg gtatagaatt gctgaatgtt ctacatcgag     5040

taattttaac cagagaatca ccttccattc agttggcttc acttgaagtg gtaaggcaga     5100

ttatctgtgc tgctcaagaa catgtgaagg aaaaaagacg aagtgcagaa gttgatgatg     5160

gggctgctga aaaggaaact ctgccagagt ttggagaggg aaaggacacc ggaggacttg     5220

tgcctggaaa gtctttggtc tttgcaacac tggaattgtg tgtatgcatt ctagttagac     5280

agctcccaga attaaaccct aaattgacag gtagcccagg agtaaaagct acgaagccac     5340

agatactatt agaagatgga agtagattgg tttcagctgc attggttatc ctttccgaac     5400

ttcctgcagt gtgctctcct gaaggaagca tctcaattct ccctactata ttgtacctca     5460

caatcggggt cctcagagag actgctgtga agttacctgg gggccagtta tcttcgacag     5520

ttgcagcttc cctacaggct ctaaaaggaa tattatcttc tcccatggcc cgggcagaaa     5580

agagccgtac tgcttggact gaccttctcc gaagtgcctt aacaacaatt cttgactgtt     5640

gggatccagt tgatgaaaca caccaagaac ttgatgaagt cagtctactt actgctatca     5700

cagtgtttat tttgtctacc agtccagaag taactaccat cccatgcctt cagaagcgct     5760

gtattgataa atttaaagct actcttgaga taaaagatcc tgtggtacaa atcaagacct     5820

accagctcct acattccatc tttcagtatc caaatccagc tgtttcctac ccatacattt     5880

actctttagc atcctgtatc atggaaaaac tgcaggaaat agacaagaga aaacctgaaa     5940

acactgctga gcttgagatc ttccaagaag gcataaaggt cttagaaaca ctggttactg     6000

ttgctgaaga acaccatcgc gctcagctgg tggcctgtct tttgcccatc ctcatttcct     6060

tccttttgga tgaaaattct ctgggatcag caacttccat aatgagaaat ttacatgact     6120

ttgctctaca aaatctcatg caaattggac ctcagtattc atctgttttt aaaagtttag     6180

tggcttcttc tccagcccta aaagcccgcc ttgaggctgc tataaagggc aatcaggaaa     6240

gtgtcaaagt caagatacca acatctaaat atactaagag tcctggaaaa aactcaagca     6300

tccaattaaa gaccagtttc ctctgatttt ttttttggaa tagtaagcac cttaatataa     6360

taaatacttg atcattgcct ttggtgacaa aagggacatt gtagacacaa gtgcccttag     6420

aggtctagtt gattgtttta ccttaaatag ctgtgactct tcaaagtaac agcatactta     6480

acatttttgt gtgtgtgcgt ggggtttgtg ttttgttttg ttttgttttt ctatttaaaa     6540

agacaatgga gctaacttgc caggaatttt aagaaagtgc taaagaacta aacttactaa     6600

acaatccact gctttaaaaa tgaaatgaat ttcttctaac agtccataca tatgtggtat     6660

acttaatact gtgacagata taaatatgac tctagtgtaa attatctgca ctaatattgt     6720

atcccaattg ctgatttaaa attctgcttt ggcccggcac agtggctcat ccctgtaatt     6780

ccagcacttt ggaaggccaa ggcgggcgga tcacgaggtc gggagtttga gaccagcctg     6840

accaacatgg tgaaaccccg tctctactaa aaatacaaaa attagccggg tgtggtggca     6900

cacacctgta atcccagcta ctcaggaggc cgaggcagga aaatcgcttg aacctggcag     6960

gcagaggttg cagtgagcca agattgtgcc actgcactcc agcctgggcg acagagtgag     7020

actccatcta aaaaaaaaaa aaaaaaattc tgccttattc agtaattgta ttaaactttc     7080

tctgatttct ccaagaagat aaaatgattg gagagctatt taggaaacct ggtctaggat     7140

tatccagtat acaatagtac aaattactta cagccttaca gtgcaacata agatttggtg     7200

tctatatcat ggttttccac catcttttgg tttagtttat attgggttca gaaattgagt     7260

cttactcatt ttaaatagaa taagccattt ccactatttt tcaaatggat ttttctgttt     7320

acctctgttc ttaccaattt tgttcatttt catttgtggc aaacatttgt atcaatgagt     7380

tttaacctag gttcatatct acattgtatt tagatcaact atgggtttat ataaatgcca     7440

aatttagtac aacaaattta ggtcatcagg tgaatacaag tatttttttt aacaggaaac     7500

attttattat agaaaaaaga ttaatgataa agtcatattg gttgaaaaat attttttaac     7560

tgtgttcatg attgttgatt ctccttctac ttcagtgtta tactgtgtga atcaagcact     7620

gtgtcaaaac agagcatttc cctcttaaaa attacaaacc gaagtgatag aagcatgtca     7680

gaattgagaa gacattttga agcaagaaca atgtgatgta cctattttat tatgtttgta     7740

tataaatact attgtaaatt gttcagagtg aaaacatttg acaaactcta acactacaat     7800

cattttttct aaattacata aataaagcta attttcatta tcaaaaaaaa aaaaaa         7856


<210>  716
<211>  4963
<212>  DNA
<213>  homo sapiens

<400>  716
ggcgcgggcg cgggcggggg cggagtggcg gcggcagcgg cggctagaag cggcagccca       60

gagccctctc gcggccgcgg cggcagcagc agcgccagcc ccagcaacac tgaggccgcc      120

gccgccgcct ggcgctcccg ccgcccggcc cgacatgagt gaggcggttc gggtaccctc      180

gcccgccact ccgctggtgg tggcggcggc cgcgcctgag gagaggaaag ggaaggagtc      240

agagcgcgag aagctgccgc ccatcgtatc ggcgggcgcc ggcgcgaccg cgggtttgga      300

cagaggagcc aaaggccaaa tttccacttt cagcagtttt atttcagctg ttagcccgaa      360

gaaagaagct gctgaaaaca gaagttcacc tgcacatctt gttttcccta acatcaagaa      420

tgtgagagaa ccaccaccaa tttgccttga tgttagacaa aaacagcgta catctatgga      480

tgcatcatca tccgaaatga aggccccagt ccttccagaa cctattcttc ctatccagcc      540

caaaactgtg aaagactttc aggaagatgt agaaaaagtt aagtcatcag gagattggaa      600

agcagtacat gatttttatc taacaacgtt tgattctttc ccagaattaa atgctgcatt      660

taagaaagat gccactgcct catttaacac cattgaagac tctgggatta atgctaaatt      720

tgtgaatgct gtgtatgata ccttacttaa tactcctcaa gacgttcaga agacagtatt      780

aaagggaatc attaacagcc tgttacgaga atggaaaggt ccacgaacaa aagatgatct      840

tagagcatat tttatacttt tacagaatcc tcagtttaat aacacatcta cgtatgtcat      900

ctatgctcac ttgctacgac agatagctac cttagtggaa gctgaccatc atttcctagt      960

tcactggttt aaaaaattgt cccagaagag gttcaaacaa ttggtagaga gattgctgca     1020

atttatttct ttacgcctgt ttcctgcaaa gcctgaagaa tttccaccta taacaaagtg     1080

ttcctggtgg attccatcag ccgctaaagt gttggcttta cttaatactg caaacaattt     1140

agttcaccct ccccttattc cttatactga tttctataat tctacattgg atcacattga     1200

tctcatggaa gaatatcata cttggcaaaa ctttggaaac tctcacaggt tttccttctg     1260

tcagtaccca ttcgttattt ctgtagctgc aaaaaaaatc attattcaga gagactcaga     1320

gcaacagatg ataaacatcg caaggcaaag tctggtggat aaagtatctc gaagacagag     1380

acctgatatg aatatattat ttctaaatat gaaagtaaga cggacacatc tggttagcga     1440

ttcacttgat gagctaaccc ggaaaagagc cgatttgaaa aagaagttaa aagttacatt     1500

tgtaggggaa gctggtttgg atatgggtgg tttgactaaa gaatggttcc ttcttctaat     1560

tcgccaaatt tttcatccag attatggcat gtttacatat cacaaggatt cacactgcca     1620

ttggtttagc agctttaaat gtgataacta ttctgaattc cgattggttg gaattcttat     1680

gggactagct gtttataaca gcatcacctt ggatattcgt ttccctccct gctgttacaa     1740

gaaattattg agccctccca tcattcctag tgatcaaaat ataccagtag gcatctgcaa     1800

tgttaccgtg gacgacttat gtcaaattat gcctgagttg gcccatggat taagtgaact     1860

cttatcacat gaaggcaatg ttgaagaaga tttctattca acatttcagg tttttcaaga     1920

agaatttgga ataatcaagt cctataattt aaagcccggt ggtgataaaa tttcagttac     1980

caatcaaaat agaaaagaat atgtacagct ttatactgac ttccttctga acaaatccat     2040

ctataagcag tttgctgcat tttattatgg atttcatagt gtgtgtgctt caaatgccct     2100

aatgctgctt cgtccagaag aggttgaaat tttggtctgt ggaagtcctg acctggatat     2160

gcatgctctg cagagaagta ctcagtatga tggctatgca aaaacggact taactataaa     2220

atacttttgg gatgttgtgc ttggatttcc tcttgatctt caaaagaagt tgctacattt     2280

tactacaggg agtgacagag tacctgtagg agggatggct gatttgaact ttaaaatctc     2340

aaagaatgaa acttctacta actgcttacc tgtggcccat acctgcttca atcaactttg     2400

ccttcccccc tacaagagca aaaaggatct gaaacagaaa ttgatcattg gaatttcaaa     2460

ttcagaaggt tttggacttg agtaacctag aagacttgaa atataatctt ttatatgtag     2520

cattcacttc cctcttactg tgcctttagc cttttcatgt ttctgtctca aaacactttg     2580

acaaagctca ccaactttaa aatattaagt ttttaaaaaa tcaaatatga agtatgttca     2640

gcaaaggcat aattttctaa aaacacacac agaaatcgct tgagtgagga aaagtccaca     2700

tggcagagac aggtatggtc cagttcctct tttatatagc actttatcat tctccacaag     2760

tagtttgtca caggcattcc actgggaaag caaagtacag tgaagaatga atttatggta     2820

tagttgaacc cagtggcaga ttgtacactg ctagcactgc tagcacacag tagcaaagca     2880

aacagctaca ttatctttaa cataaggcat gtagccatat tttcatatag tggtatacaa     2940

cacagtatca ttgcaaatgc agtttacagg gatttttgat atactggctt gggacctata     3000

agattcttct cagcagttgc tgaaaagcat gtaaataact acataatagc ctgagaataa     3060

tgggattttg atagtgccat ttattgttaa agatttattt ttacaaagta aattcagggt     3120

tttagatgtg tacacagctt ttacaaatca ataaagatga ttgtacaaga gtattttcag     3180

actaattgga ttcaaggtta tattctttta agtgttgtta gtctgcatgc acattggcag     3240

taaactagtt acttgtgtac tctgtaatat ttgtataatg atcatttctt cttaaggctc     3300

aagatattag aaaagaaatc agacctaaat aatcattgat gaagtatgtc agttacaagc     3360

acaaaagaat ataactgctt ttataaatct tttgaatcat gtacaagact tatatctaca     3420

ttttttgatc accagttgta ccaaaacact aatttttgaa aaagataggt taaagtattt     3480

gacaaaagtg aatacaataa taacacttgt gtcaaaatga tatagcttag tataaaaata     3540

aaattcaacg ttttggccaa aatgtttgtt tttcactgga ttctgaatat aataaattca     3600

aagtaccctt tttttagagt ttctaataaa gtagtatgta aaaagaaact gcattttaag     3660

tcagacagta aatgtttttt ttaatttaca gcaaatgaag cagttttatt agcatgttac     3720

aaatattgcc aaaccaagac ttctctacca tactttaaca gctttccttc agaaaactct     3780

gaagttatat ttgcaataat aatgaaacca gcatttagta ccagcatatg gttcatatgc     3840

aaataatact ttccccaaaa tctttctggg ctaggctatt ttcttgctat gcttcctgca     3900

cccaaccagc agaattcttc cagggtggag gaactaatca gcttgttctc caacagttct     3960

gaagccaacc cacaaatctt tgaggaaaag gggtcacttt gtttactatt ctcttggaga     4020

tggaagtgat tctgctcttc catttgggta tattatttca agggtatttc ttcttaaaaa     4080

tcttggaaag cctaagagag ttaaaggcat cctggttttg tttcattttg ctctgtttta     4140

aatccatatg caaataaaac tgcttctctc ttacactgct tgaactagaa aatcagcttt     4200

ttaatgtagg ttaccactta taagcacaaa agaaacatgt ataagaaacc agatttaagt     4260

gttttaaata aaatgtaaac agtttttatt tggtagagat gactcatgga aaaattgtgt     4320

tggcttggtc tgcatgttta atgatgtgct tgtatatcga ttagctgtgt cacttttaaa     4380

taagaagtcc acacaagcaa gccaaatttt tagatgacga agtccataaa taactagaga     4440

atttttgtta tctgttgtta agttgaaatg tataatcatt tatcactaaa ttgcacattg     4500

cctttattta tttgtgctct gtttttggtt tacagtgtaa taatacctca tttaaaaaat     4560

aaaaaccact actgttacat tttattaatt taaaaagcta gaaaattcat gtagttactt     4620

tttttacata tataatctgt taatgaatta ttgatttttg tatctgccac agtaaattaa     4680

agcattacac agtatttatc agtatttttt aaacatcctg tcctttttta aaatctttgc     4740

ttagtcagtc atatttttgt ctgtatgatt agaagttttt acgtccttcc ttttttgtac     4800

aaatctgtat tgtattaatt tctggatgca atttttcaaa tattaaaatt atacagtcag     4860

tcaggcttca gtttattttt tgaacacttg ggcaattaat taaagccata tgtttaaaat     4920

attttataaa aaaaaaaaaa aaaaaaagaa aaaaaaaaaa aaa                       4963


<210>  717
<211>  2234
<212>  DNA
<213>  homo sapiens

<400>  717
ggcgcgggcg cgggcggggg cggagtggcg gcggcagcgg cggctagaag cggcagccca       60

gagccctctc gcggccgcgg cggcagcagc agcgccagcc ccagcaacac tgaggccgcc      120

gccgccgcct ggcgctcccg ccgcccggcc cgacatgagt gaggcggttc gggtaccctc      180

gcccgccact ccgctggtgg tggcggcggc cgcgcctgag gagaggaaag ggaaggagtc      240

agagcgcgag aagctgccgc ccatcgtatc ggcgggcgcc ggcgcgaccg cgggtttgga      300

cagaggagcc aaaggccaaa tttccacttt cagcagtttt atttcagctg ttagcccgaa      360

gaaagaagct gctgaaaaca gaagttcacc tgcacatctt gttttcccta acatcaagaa      420

tgtgagagaa ccaccaccaa tttgccttga tgttagacaa aaacagcgta catctatgga      480

tgcatcatca tccgaaatga aggccccagt ccttccagaa cctattcttc ctatccagcc      540

caaaactgtg aaagactttc aggaagatgt agaaaaagtt aagtcatcag gagattggaa      600

agcagtacat gatttttatc taacaacgtt tgattctttc ccagaattaa atgctgcatt      660

taagaaagat gccactgcct catttaacac cattgaagac tctgggatta atgctaaatt      720

tgtgaatgct gtgtatgata ccttacttaa tactgtaagt attatgacat gcaagtaata      780

ttattctgtg tctcttctgt atatcaaaag cagccataca aatattgtaa aaatcacctt      840

ataattacct tagaaactct gatacaattt tatagtaaat gtagctggaa ttctcataaa      900

gttagattat tttattcttt tattttttaa ttatgaatta agcagcaaat acttttatat      960

ccaatccttt tttagaaaga cttgctaaaa tcatgcttta cttactcagc aaaaggaggt     1020

aagttattta attatattgg aattacactg aatctgtaga tcagtggttc ttaaacatta     1080

gcctgtatca gaatcacaag aagggcttgt taaaatacag aatttcagat tcagtaggtc     1140

ttgggtgaag cccaagaatt ttcatttgta acaagttccc aggatatgtt gatttatgag     1200

ttcatttatg atgtgacaca tactataaaa attatgtcac cattcaaaaa atccagatgc     1260

atatttgaag gactaagtgg gaatgataaa gacagaatgt aaacaaagtc tccagaagtt     1320

tagctatgaa gtgaaagaca tgttaagaat gaccacattt tgagaaccat actgctatag     1380

atcaatttgt gaaaaattga catcttttca atccataagc atactgtatc cttttaggta     1440

cctaggtctt ctttaatttc tcttggtaat gttttgtagt tttctggata gaggtgttac     1500

acatttctca ttacatgtat ttctaggtac ttcatttttt ttatcctatt ataattttat     1560

tttccaattg tgactaatat atggaaatac tttcatatat ttatctttat ctaaatacag     1620

ttgacccttg aacaatgcga gggttagggg cgctaacccc ctatgcagta aaaaaaaaaa     1680

tctgtgtata acttttgact ccccagaagc ttaactacta ataacctatt gttgaccaga     1740

agtcttactg ataacataaa cagtcaatta acgtatattt tatgttatat gtattctata     1800

ctatattgtt acaataaagt aagctaagga aaaggcaatg ttattaagaa aaaataagga     1860

agataaaata tatttactat atattaagtg gaagtggact atcataaagg tcttcatcct     1920

tattgagtag gctgaggaag aggaggggtt ggtcttgctg tctcaggtgg cagaggtgaa     1980

agaaaataat gtatataagc agacttgcac aattcaagcc tgtattcaag agtcaactgt     2040

actttgctat attcatccat taattctaat agtacatcag taaattaact tggattttct     2100

gtgtacacaa tcttgtcatt tgtgaaaaag gagagtttta tctccttcta atcctgtatc     2160

ttatatggat atatgtatgt gtttgcattg actgggacct ctttcacaat tgtgaataaa     2220

agaagtaata gcag                                                       2234


<210>  718
<211>  558
<212>  DNA
<213>  homo sapiens

<400>  718
ggtcccctcg gggcttcccc ttgggtctca gcgcaaagtc gggcggcggg gccggatgga       60

cccgaggcgg acgaataacg aggagctgcg agacgccacc ttcttgctgg cggcggggga      120

gggcggcttg ctagacgacc tggagcgtct gtcaggctag gaggaggggg aggagagctg      180

agagtttcat tctgtcgccc aggctggagt gcaatggcgc gatctcggct cactgcaacc      240

tctgtctccc aggttcagga aaatggcttt gtaaagaagc ttgagcctaa atctggctgg      300

atgacttttc tagaagttac aggaaagatc tgtgaaatgc tcttctgtcc tgaagcaata      360

ctgttgacca gaaaggacac tccatattgt gaaaccggcc taatttttct gactcttacg      420

aaaacgattg ccaacacata cttctacttt taaataaaca actttgatga tgtaacttga      480

ccttccagag ttacagaaat tttgtcccta tttaatgaat aaattgtatg tatttttctc      540

tataaaaaaa aaaaaaaa                                                    558


<210>  719
<211>  3188
<212>  DNA
<213>  homo sapiens

<400>  719
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtaatg     1560

ggactcctga ccaaccacgg tggggtacct catcagcccc agactgatta cgcgctctcc     1620

cctctcaccg ggggtctgga acctaccacc acggtgtcgg ccagctgcag tcagagacta     1680

gaccatatga agagcttgga cagtctgcca acatctcagt cctactgtcc acccacctat     1740

agcaccacag gctacagtat ggaccctgtc acaggctacc aatatgggca gtatggacaa     1800

agtgcctttc attatctcaa gccagatatc gcttggtttc aaatcctttt gaacacgttc     1860

gacaaaagca gtggagaaga ggaagacctg gagcaataaa agacaaatgc aacattttaa     1920

ggcaatggtt tcacatggtt acatatcaaa acatcccaat tctttagtgc tgatcatcga     1980

ggagctagaa cattccattt gcttgtgtgc gtgcgtgcgt gtgtgtgtgt gtgtgtgtat     2040

tgagatttac ccagactggt ttgggcaagc agactgttct aaaatataat agaataccct     2100

aaagtataac atgtcgatgt tcgatgctga tacttctaca actttaaaac tgctcatttc     2160

atgaagcaag aatggaggaa tccttgactc ttacacactg gaaattgaaa taaagataaa     2220

tgcaaccatt tttaggaagc tagactagct gtaaaggacc tcctaaataa attatttgtt     2280

actgtatcct catttgtaat ctagttgtca ataaatggcc cggacatgtc ttgctaacag     2340

gatatgggct accaggaaga aggacttgtt tccctttcct gtgtggggag aggtgtgtga     2400

cgtttttcca gttcacattt atttggtagc ccacctgggt tggaggaagg gcacggtgga     2460

gagaaagtga catgcattca catatctgct tatcagtgtg caatactgtg tacctcatgg     2520

atgctttggc aatgcccaag gcgatataag caaaatcaga agtatatttt tgcaggtgct     2580

tttattttca cagcccataa ttcatagtga tagagtgcag tgatgtttgc catttgctgg     2640

acaaccaaca cccgggttgc tcctttgatt agagaccaga tcagataatt atgcttttaa     2700

actgattacg tttacattct tctcttttct atgaaaggca gggcaagaac agaagtgttc     2760

acatggctct catgtacttt taaattatac aatgatatcc aatattaaaa gattatagga     2820

actgaggttt acatacgttt gtgtggtgac attttagaat gtcaataaat ttgctttttg     2880

agatgttgag aggaacaaga aggtggaagg cagtgttatt tatttctttc tattcttgga     2940

accacgaatg aggtaggcac aaatacattc cttttagagt taagaactat gacgtagcga     3000

gttagtgaga ctagacatag taccgaattt agttcatgca ttggtcttag agggtgatgg     3060

aacaagagaa gtactatctt tgtgttgcag cctcaaccaa caacaatgtg ttgtaaaaat     3120

gtctttcatg taaaaagtgc agtaaatatt tactatttat aatgaataaa cagttatgaa     3180

aacttgaa                                                              3188


<210>  720
<211>  9243
<212>  DNA
<213>  homo sapiens

<400>  720
atttcatttc ttccactaaa gcgtttgcgg agacttcaag gtataatcta tcccagatcc       60

tttcccagag agaaacttgg cgatcacgtt ttcacatgat gctcacgctc agggcgcttc      120

aattatccct ccccacaaag ataggtggcg cgtgtttcag ggtctctcgt ctctctccta      180

cagaaaagaa aaagaaaaaa atgtcattag aagaggcgta acacgtcagt ccgtccccag      240

gtttgtgttt cctggagtgg ccgaaagaga tcagttctaa cctgctctgc aggaataacg      300

gtcctgcctc ccgacactct tggcgaggtt tttgtacagt ttgctccggg agctgtttct      360

tcgcttccac ctttttctcc cccacacttc gcggcttctt catgcttttt cttctcacca      420

tttctggcca aaactacaaa caagacttcg cagatcgagc ctgcgtgctg ccgaagcagg      480

gcgccgagtc catgcgaact gccatctgat ccgctcttat caatgaagca gccgatcatg      540

gcggatggcc cccggtgcaa gaggcgcaaa caagccaatc ccaggaggaa aaacgtggtg      600

aactatgaca atgtagtgga cacaggttct gaaacagatg aggaagacaa gcttcatatt      660

gctgaggatg acggtattgc caaccctctg gaccaggaga cgagtccagc tagtgtgccc      720

aaccatgagt cctccccaca cgtgagccaa gctctgttgc caagagagga agaggaagat      780

gaaataaggg agggtggagt ggaacacccc tggcacaaca acgagattct acaagcctct      840

gtagatggtc cagaagaaat gaaggaagac tatgacacta tggggccaga agccacgatc      900

cagaccgcaa ttaacaatgg tacagtgaag aatgcaaatt gcacatcaga ttttgaggaa      960

tactttgcca aaagaaaact ggaggaacgc gatggtcatg cagtcagcat cgaggagtac     1020

cttcagcgca gtgacacagc cattatttac ccagaagccc ctgaggagct gtctcgcctt     1080

ggcacgccag aggccaatgg gcaagaagaa aatgacctgc cacctggaac tccagatgct     1140

tttgcccaac tgctgacctg cccctactgc gaccggggct acaagcgctt gacatcactg     1200

aaggagcaca tcaagtaccg ccacgagaag aatgaagaga acttttcctg ccctctctgt     1260

agctacacgt ttgcctaccg cacccagctc gagcggcata tggtgacaca caagccaggg     1320

acagatcagc accaaatgct aacccaagga gcaggtaatc gcaagttcaa atgcacagag     1380

tgtggcaagg ccttcaaata taaacaccat ctgaaagaac acctgcgaat tcacagtggt     1440

gaaaaacctt acgagtgccc aaactgcaag aaacgtttct cccattctgg ttcctacagt     1500

tcgcacatca gcagcaagaa atgtattggt ttaatctctg taaatggccg aatgagaaac     1560

aatatcaaga cgggttcttc ccctaattct gtttcttctt ctcctactaa ttcagccatt     1620

acccagttaa gaaacaagtt ggagaatgga aaaccactta gtatgtctga acagacaggc     1680

ttacttaaaa ttaaaacaga accactagac ttcaatgact ataaagttct tatggctaca     1740

cacgggttta gtggcactag tccctttatg aatggtgggc ttggagccac cagcccttta     1800

ggagttcatc catctgctca gagtccaatg cagcacttag gtgtagggat ggaagcccct     1860

ttacttgggt ttcccaccat gaatagtaat ttaagtgagg tacaaaaggt tctacagatt     1920

gtggacaata ctgtttccag gcaaaaaatg gactgcaagg ctgaagaaat ttcaaagttg     1980

aaaggttatc acatgaagga tccatgctct caacctgagg aacaaggagt tacttctcct     2040

aatattccgc ctgtcggtct tccggtagtg agtcataatg gtgccactaa aagtattatt     2100

gactatacgt tggaaaaagt caatgaagcc aaagcttgcc tccagagctt gactactgac     2160

tcaaggagac agatcagtaa tataaagaaa gagaagctac gtactttaat agatttggtc     2220

actgatgaca aaatgattga gaaccacaac atatccactc cattttcatg ccagttctgt     2280

aaagaaagtt ttcctggccc catccctttg catcagcatg aacgttacct ttgtaagatg     2340

aatgaagaga tcaaggcggt cctgcagcct catgaaaaca tagtccccaa caaagccgga     2400

gtttttgttg ataataaagc cctcctcttg tcatctgtac tttctgagaa aggaatgaca     2460

agccccatca acccatacaa ggaccacatg tctgtactca aagcatacta tgctatgaac     2520

atggagccca actccgatga actgctgaaa atttccattg ctgtgggcct tcctcaggaa     2580

tttgtgaagg aatggtttga acaacgaaaa gtctaccagt actcaaattc caggtcccca     2640

tccctggaaa gaagctccaa gccgttagct cccaacagta accctcccac aaaagactct     2700

ttattaccca ggtctcctgt aaaacctatg gactccataa catcaccatc tatagcagaa     2760

ctccacaaca gtgttacgaa ttgtgatcct cctctcaggc taacaaaacc ttcccatttt     2820

accaatatta aaccagttga aaaattggac cactccagga gtaatactcc ttctccctta     2880

aatctttcct ccacatcttc taaaaactcc cacagtagtt catacactcc aaacagcttc     2940

tcttctgagg agctccaggc tgagccttta gacttgtcat taccaaaaca aatgaaagaa     3000

cccaaaagta ttatagccac aaagaacaaa acaaaagcta gtagcatcag tttagatcat     3060

aacagtgttt cttcctcatc tgaaaactca gatgagcctc tgaacttgac ttttatcaag     3120

aaggaatttt caaattcaaa taatctggac aacaaaagca ctaacccagt gttcagcatg     3180

aacccattta gtgccaaacc tttatacaca gctcttccac ctcaaagcgc atttccccct     3240

gctactttca tgccaccagt ccagaccagt attcctgggc tacgaccata cccaggactg     3300

gatcagatga gcttcctacc acatatggcc tacacctacc caactggagc agctactttt     3360

gctgatatgc agcaaaggag aaagtaccag cggaaacaag gatttcaggg agaattgctt     3420

gatggagcac aagactacat gtcaggccta gatgatatga cagactccga ctcctgtctg     3480

tctcgcaaaa agatcaagaa gacagagagt ggcatgtatg catgtgactt atgtgacaag     3540

acattccaga aaagcagttc ccttctgcga cataaatacg aacacacagg aaaaagacca     3600

catcagtgtc agatttgtaa gaaagcgttt aaacacaagc accaccttat cgagcactca     3660

aggcttcact cgggcgagaa gccctatcag tgtgataaat gtggcaagcg cttctcacac     3720

tcgggctcgt actcgcagca catgaatcac aggtattcct actgcaagcg ggaggcggag     3780

gagcgggaag cggcggagcg cgaggcgcgc gagaaagggc acttggaacc caccgagctg     3840

ctgatgaacc gggcttactt gcagagcatt acccctcagg ggtactctga ctcggaggag     3900

agggagagta tgccgaggga tggcgagagc gagaaggagc acgagaaaga aggcgaggat     3960

ggctacggga agctgggcag acaggatggc gacgaggagt tcgaggagga agaggaagaa     4020

agtgaaaata aaagtatgga tacggatccc gaaacgatac gagatgaaga agagactgga     4080

gatcactcca tggacgatag ttcggaggat gggaaaatgg aaaccaaatc agaccacgag     4140

gaagacaata tggaagatgg catgtaataa actactgcat tttaagcttc ctattttttt     4200

ttccagtagt attgttacct gcttgaaaac actgctgtgt taagctgttc atgcacgtgc     4260

ctgacgcttc caggaagctg tagagaggga cagaaggggc ggttcagcca agacagatgt     4320

agacggagtt ggagctgggt attgttaaaa actgcattat gcaaaaattt tgtacagtgt     4380

taaggcctaa aaactgtgtg gttcagagac taattcctgt gtttaatagc atttatactt     4440

taagcacaac tagaaaattg taagaattgc actctactta tgtatcacta caaactttaa     4500

aaaactatgt ctaatttata ttaatacatt ttaaaaaggt gcccgcacta ccatacatca     4560

gtatttttat tattattatt gttattcctt tttaatttaa tgtgctcgca ctacaatgca     4620

tcagtattat gattcctctg tactttcctt tcgctattca tcaatttccc attttttttt     4680

tcagcttaag taaccacaca attttaggcc tcaatttttt tttttttctg tgaaggaact     4740

tgaagtgatg catgtgtgaa tttaagatac cgaagtctta aagtgacctg gacgtgaagg     4800

aaaaagtaag atgagaaata aagaaagcct ttgtaaggtg gttttaaaag ccttatatgc     4860

aaacctttta atctgtgttt ctgcaagtgc catccttgta cagtgttaag agggtaacat     4920

gggttacctt tgcaccagct tcagtgttaa gctcaccctg ttctttgaag cacccatgtc     4980

agtattagaa gaataggcag cagttcctta gtttacatat gtttgtgcaa ttattttctg     5040

tacttttttg ttcattaatt ttgtcagtat tacaccaaac tgtttttgca acaaaaaaat     5100

tttttttgca ttcatttaat tttaggtcaa ataacatttt atttatgtgg ctcattttat     5160

atttcctaat tttatttatt tcatactgta gtgtacagta ttatagttct tcaatatata     5220

gatatatttt agtaaaaaag gaacatgacg ttgatcattt gggcaaattt tacgtaaaga     5280

gaagagcatt tattgtgttt tggaacatta attgtgagat gggatttttc aattttatta     5340

ttttattttt gtttttttcc aattactgga aattccaaat ttgggaactt ttgatacgat     5400

cttgtgaaaa cactgtattt tcgactgaaa attccacttt cttcatcttg ttttttagct     5460

aaaaagaggg actgttaaat acaatgtatg ataccatgac aaaaatcttt cctgaattgt     5520

ctttgtaaaa gtattattga attttcaatt tgtaatttct tttgaaaatg accatgctcg     5580

aataaaaatg tagccaaact aagaatgtag ttaatgagtt ctgtactttt agagagtttt     5640

ccttcaatga ccattaacat gtaacatgct ttatgcttat aataatgcta attatgtttt     5700

tttcatataa ttttagttta gcaataattt tgactggtac caataactgt tttttaaaat     5760

tccataccta tgtacagcaa ttttacagct tttctcaact gatcctgatt ccagattgtg     5820

tatttttatg tgaggttata ttattcaaat ttagtctatt tactttacag acatttctac     5880

ttttgcatta cgagtattta gagattatgt gttaaaaatt cacttctctg tccaaggggt     5940

ctttgtgatt tattcaaaaa aaagtctaat ttcaaaaaga cagctattat tcagtgttat     6000

ttataatatg taaccttttt taaaggattg ggatagttta tctcactttt tgaaatgcag     6060

acagtagttt accgtttatc tgaaactaga aggcgtgggt gggagaggaa aagctaaaag     6120

caaatgctaa caaaaataac cgtgattttc taagacagtt tttcagtttt tacaagatga     6180

ccctaatatt cagaatatga atgtattcgt aggttttaca taatgacttt tatcaagaaa     6240

ctagattctg cttcttaaat ctaattgcca agtgaagaat aacagaaaaa acagattacc     6300

ttatcaaatt tacagctctt gaatatacag aactataata tagtagctgt ccatgtattt     6360

tttctacttt agaatcaaag aagaaaagca tcattttgct attaaatttg ctaaaatttt     6420

gagtatgata tttccagttg gcaagaacaa catatttata tttattcctt agccataata     6480

ccactttcct aaatttcaca aaagtcattc tttgcaactt gaaactcaat agaaagtgtg     6540

tatgtgtgtg tgtgtatata tatatatata tacacacaca cacatacaca gaaaggatgt     6600

aatgaagata cagtaatagt tgagcagacc tttttagaaa aacatgtttt tagctctatc     6660

ttcaaacttt ctggcagagg gggtgggggg ggcaggggga ggagtggcat caaaatgcta     6720

tgcctcctgt tatccacagc ctagagtttt tatatttgga aagtttagaa aattctatcc     6780

tcgtttctcc ttctttgaat ggcacaaata aatacactac ataaattttt ctggtttgaa     6840

aggctctagg cgataacttt attaattcaa cctgaaaata tcaagccatt aaattttgtc     6900

cgggtagaat aaatccctgt ggcctctttt aaagcaatgt aggtctctgt tgcccatggg     6960

gcatatctgt gtcccaatcc acaagagata ggaccaacaa acaatgaatg tgcaacctaa     7020

ctctttctcc ttggaaagaa gaaagtgtgc acgaagtaga ggagggtggg cagaccctgc     7080

cttgcccctc ctgttacccc cttctctgtc atttgttcct aactccattt cataggcagg     7140

ctcagaatac ctgagtctga aaatatcagg ataacacttg tgaattgtga caatcactac     7200

aatgtcccat atctgaggag ttttttttaa tgctatttat ccgctggaca cgattgcaca     7260

ttagggctgc ataatcctct aactctaggg aaaaataaaa acttttgatt tgtcttaaga     7320

ttcttctcca aggtcgcaaa caagaaattc ccctccacaa ccaagagatg tgcattttag     7380

taacatcaga tgtgttcttc tgttttatca actacttact cttcccacac gcttagttct     7440

aaatctaacc tttcccccct cgaatagggg gcaggggagg atgaggaaac actggaacaa     7500

ctgaacaccc ctgcccattt tctccaagag ccttttgtat tctagcatat ctgtgcaatc     7560

ttttcttttt tcttcacatg acactgtaag cttaggcctg aaataactgg gaagagagat     7620

gcgtatcaga atttctccgc aagagctaaa caaaacatac atcttcctta gcatgaattg     7680

gactgggggc ggagtgggag ggcttggagg aaaggggaaa gaagggacta tatttgaata     7740

aatatgaata aatgtattag atacttttca caatcagata acttttaaaa aggtcatttt     7800

ttatctttct aataatgtaa gccttaataa aagcaaatct tagtcacaaa tttgaggaga     7860

ctgcccaata ataagtttac atgtatttga actgaaaaat tgttaaccat gcttttgctc     7920

caagatgtgt gaggccattc aggggctgta gggccctgga tatacacaca aacaagtgtg     7980

tgtatatctg gagccccaca cattgtaata aacacagctg catttatttg actatgtgat     8040

cccatgtaca tgtaaaaaca ttcaaacaaa cacactcagc ggatttattt attgtgcaat     8100

ggggcaatta ttcaaataaa catgctcaat gcaattattt gaatctcaca ttgcatgttc     8160

atcaatcata gcactaaaaa aagaggggga aaaaacacca aagaattcac atggggaaaa     8220

aatatatata tgaaaaccac cttattatag attttatagg gcagctgagg ttatggctcc     8280

cttcttaact gtaactcaac tattctgtat tcaatgacat ttgtttctaa tgattaattg     8340

gttcactcac ttgatcatat aatagcaaac tttataaacc tgtattgtgt agagatgtga     8400

aatctctata tttcaagagc agaagagttc tttctagaca ccttacatca agggacactg     8460

gtccaattat tatcgcttat ataagcactc ctataaattc tgaaaaattt tatacatgca     8520

acaaaacatt cctacatttg aagacattaa gaaaaatcac aggtgactca tctgatcatt     8580

ctatatatta ataaatatta tgacatatat gtgaacacat cacaaatcat attggtgtac     8640

caagaggcaa tttatgcctc tcttaagtat gtactgacat aacctaatat actaaaatgg     8700

gaaggggctt ttagtcactg aaatatgcat cgtgtaacaa agatgaagaa aatacatggc     8760

ttgtgcccat cataaaaaaa gattcagact gaaggcttag ctttggtttt ttcaattaaa     8820

ttgttaaact gtgcacagtg attttttttt agaacttgag acatttgtga tgttggctgt     8880

ttaaatcttt gttaccttcg ctgtgaattg aaattgtaca tatttagtaa atcatgcaga     8940

caaaacaaac tttttagaca atatttttat tggagagttt tcttttcctg tatccatgtt     9000

aaaaaaaaaa aagacctcct ttcccaaaat aaaaatgtca atactaaatt taaagaagta     9060

taaaggaatg attgcttcct ttagagcaaa atatttaaat aaacatggag ataattggca     9120

acatgttctt tttgggctag taggctgtgt ccaatttttt gggtctgatg tttcagaggg     9180

cctctgtttc agggttgaag atgatatatt aatctcggaa ttaaacaaat gctattaaat     9240

aac                                                                   9243


<210>  721
<211>  7670
<212>  DNA
<213>  homo sapiens

<400>  721
acacacacgc gccctcaccc gccaccgccg ccgcggccgc cgccgcaccc ggacagcgag       60

cggctgaggc cgccagggcc caaaggacag cggcccagac aggggctggc ggcccggccg      120

gccccggctc accgactcgg gcagcatcca cctgccccag ccaacaccct tctctcgccc      180

caggtccttt ctcagcctcc agctgggctg tccccaagct gagctgaggc tcttctcctc      240

cgatccccac ctctgcccgg acatccacca tggggacagc caccaggagg aagccacacc      300

tgctgctggt agctgctgtg gcccttgtct cctcttcagc ttggagttca gccctgggat      360

cccaaaccac cttcgggcct gtctttgaag accagcccct cagtgtgcta ttcccagagg      420

agtccacgga ggagcaggtg ttgctggcat gccgcgcccg ggccagccct ccagccacct      480

atcggtggaa gatgaatggt accgagatga agctggagcc aggttcccgt caccagctgg      540

tggggggcaa cctggtcatc atgaacccca ccaaggcaca ggatgccggg gtctaccagt      600

gcctggcctc caacccagtg ggcaccgttg tcagcaggga ggccatcctc cgcttcggct      660

ttctgcagga attctccaag gaggagcgag acccagtgaa agctcatgaa ggctgggggg      720

tgatgttgcc ctgtaaccca cctgcccact acccaggctt gtcctaccgc tggctcctca      780

acgagttccc caacttcatc ccgacggacg ggcgtcactt cgtgtcccag accacaggga      840

acctgtacat tgcccgaacc aatgcctcag acctgggcaa ctactcctgt ttggccacca      900

gccacatgga cttctccacc aagagcgtct tcagcaagtt tgctcagctc aacctggctg      960

ctgaagatac ccggctcttt gcacccagca tcaaggcccg gttcccagca gagacctatg     1020

cactggtggg gcagcaggtc accctggagt gcttcgcctt tgggaaccct gtcccccgga     1080

tcaagtggcg caaagtggac ggctccctgt ccccgcagtg gaccacagct gagcccaccc     1140

tgcagatccc cagcgtcagc tttgaggatg agggcaccta cgagtgtgag gcggagaact     1200

ccaagggccg agacaccgtg cagggccgca tcatcgtgca ggctcagcct gagtggctaa     1260

aagtgatctc ggacacagag gctgacattg gctccaacct gcgttggggc tgtgcagccg     1320

ccggcaagcc ccggcctaca gtgcgctggc tgcggaacgg ggagcctctg gcctcccaga     1380

accgggtgga ggtgttggct ggggacctgc ggttctccaa gctgagcctg gaagactcgg     1440

gcatgtacca gtgtgtggca gagaataagc acggtaccat ctacgccagc gccgagctag     1500

ccgtgcaagc actcgcccct gacttcaggc tgaatcccgt gaggcgtctg atccccgcgg     1560

cccgcggggg agagatcctt atcccctgcc agccccgggc agctccaaag gccgtggtgc     1620

tctggagcaa aggcacggag attttggtca acagcagcag agtgactgta actccagatg     1680

gcaccttgat cataagaaac atcagccggt cagatgaagg caaatacacc tgctttgctg     1740

agaacttcat gggcaaagcc aacagcactg gaatcctatc tgtgcgagat gcaaccaaaa     1800

tcactctagc cccctcaagt gccgacatca acttgggtga caacctgacc ctacagtgcc     1860

atgcctccca cgaccccacc atggacctca ccttcacctg gaccctggac gacttcccca     1920

tcgactttga taagcctgga gggcactacc ggagaactaa tgtgaaggag accattgggg     1980

atctgaccat cctgaacgcc cagctgcgcc atggggggaa gtacacgtgc atggcccaga     2040

cggtggtgga cagcgcgtcc aaggaggcca cagtcctggt ccgaggtccg ccaggtcccc     2100

caggaggtgt ggtggtgagg gacattggcg acaccaccat ccagctcagc tggagccgtg     2160

gcttcgacaa ccacagcccc atcgctaagt acaccctgca agctcgcact ccacctgcag     2220

ggaagtggaa gcaggttcgg accaatcctg caaacatcga gggcaatgcc gagactgcac     2280

aggtgctggg cctcaccccc tggatggact atgagttccg ggtcatagcc agcaacattc     2340

tgggcactgg ggagcctagt gggccctcca gcaaaatccg gaccagggaa gcagccccct     2400

cggtggcacc ctcaggactc agcggaggag gtggagcccc cggagagctc atcgtcaact     2460

ggacgcccat gtcacgggag taccagaacg gagacggctt cggctacctg ctgtccttcc     2520

gcaggcaggg cagcactcac tggcagaccg cccgggtgcc tggcgccgat gcccagtact     2580

ttgtctacag caacgagagc gtccggccct acacgccctt tgaggtcaag atccgcagct     2640

acaaccgccg cggggatggg cccgagagcc tcactgcact cgtgtactca gctgaggaag     2700

agcccagggt ggcccctacc aaggtgtggg ccaaaggggt ctcatcctca gagatgaacg     2760

tgacctggga acccgtgcag caggacatga atggtatcct cctggggtat gagatccgct     2820

actggaaagc tggggacaaa gaagcagctg cggaccgagt gaggacagca gggctggaca     2880

ccagtgcccg agtcagcggc ctgcatccca acaccaagta ccatgtgacc gtgagggcct     2940

acaaccgggc tggcactggg cctgccagcc cttctgccaa cgccacgacc atgaagcccc     3000

ctccgcggcg acctcctggc aacatctcct ggactttctc aagctctagt cttagcatta     3060

agtgggaccc tgtggtccct ttccgaaatg agtctgcagt caccggctat aagatgctgt     3120

accagaatga cttacacctg actcccacgc tccacctcac cggcaagaac tggatagaaa     3180

tcccagtgcc tgaagacatt ggccatgccc tggtacaaat tcggaccaca gggcccggag     3240

gggatgggat ccctgcagaa gtccacatcg tgaggaatgg aggcacaagc atgatggtgg     3300

agaacatggc agtccgccca gcaccacacc ctggcaccgt catttcccac tccgtggcga     3360

tgctgatcct cataggctcc ctggagctct gatcctggaa cccctccctc tgcgccgcag     3420

ctggacgcca cctccgacgg acacagccag ccccttcctg ctgccaaggt ggcctgacac     3480

tgtgccagag agtggctggt tttaaatacc tactttaaac agtgcccttt ttgtaggagg     3540

taggatattt tatattctgc cgcaggatag aacccacgca aggattttct ttaaattgag     3600

aggcaccagg cagtaacttc catgatgaca ctgacgccta tacctgagct ctaggctgcc     3660

tggagggaag gaacaggccc atgggaagaa gggggtttta aaaacatgtc ttcaactcag     3720

cagagatggc cctctgggac cctatacgga ctccgccact tgagagcagt cctaggcccg     3780

gcaggaacac cagacatgaa caggttgaag aactggagcg aagtgcacac ctcaccatcc     3840

ttcagtctaa ggaagaaggg caagccctgg gaccaagagc tctcccgcct tctccctcga     3900

gcagcagcaa ggaccctgac gctgtccccg ataactccct aggggctcct gcctgcccaa     3960

gcggctgaga accagcgccc cgatgcctga ggctgggagc ctgagcccct tcagctttga     4020

ggggggtgat actccaggct gtttggggtg ggagccaaaa agagttgaga ggccagggcc     4080

cttggtggaa aggggcacca gccttggtct gagatagtca caacccaggt gacgatgccc     4140

tctcagccaa cactgccaac ctgaccctgt catcccgatt gacagcgcca cttcaggtgg     4200

ctgggtgact aaagggcttg tcttggtggg gtctcccacc cctccaagac ccattctgca     4260

cagtccctcc agggtttggg caggagatgg ccaatcatgc gcccacctct ccagtgctgc     4320

ctgcagtcag ctcggcctcc ccgacctgca gccccagact ctgctctccc agcactgact     4380

cactcctgcc tgggagggga atgcagcatt catgctgtgt gtcctggtat tgggaggttt     4440

ctgggaaggg cagaggataa atgtggccct gcctgctccc aggtatacct aggaccacct     4500

ggccagatcc gctcccagac ggccttggac tgcttgcatt tccccggaga aaaaggggtt     4560

aataaatggg ccatcctttc ctgagctctg ggtatactac cagtcacaga acgtcagagc     4620

tggaagaagc cttagagctc aacttcttca agcccctcac tttacagatg aggaaatgga     4680

ggtggtccag agagggtctg ggattcccaa ggtcacacag cccagaagag atggggctgg     4740

gttaagaact cgagtcttcc acctttctgt tcaaggctgt ttgtctaccc agaggaagga     4800

ggcactgctg aatggctatg gcctggctaa gaaggtgatt agtcagtagg gtgtgaaaat     4860

tctacttcaa ggggttcgga ttggtgatca tggggattgg catggctggg ttcccgtcca     4920

aggtgtgggc agagcttcta ccaaacttca acatggaggg ctgacttgaa gctccctgtc     4980

cccctcactc ttgccccaag aaaagaggcc aaagcaagag cagattccct aggcaagagc     5040

agcagcacaa ctaggaaacc ccaaagccca tgctccgaca ggtggccctt cacagggggc     5100

agcgggacag gcatcttgaa gggcatatgt cctcggaagc tccgagcctg ttttctgtag     5160

tttatagtta gagctctatt ttgttatggt tttttaaact tttaagtcct gctctatttt     5220

cctgggcagg tttatgttga tgtttaccca ctacaatttt ttaaaaatat aagctcacat     5280

gccttttccc tgccacagcc aaacccccac tgcaccctac ccacccaccc ctagcccagg     5340

tcagctttcc tggagctggc taatgaaagc ctcctcacct cttcccaacc cttacaagca     5400

agggtgctag gggctcagct atacgaccat tctccctgac agggagtcca aacttggcct     5460

agcatccctc ctggcccccc tctggccacg acttggcctg tgcctggttc tctatcagaa     5520

aggggatgct gaacaaaacc tccttccaag ttttatccaa ttcgttcctc attgcctcgg     5580

gctgcgtcag gggaagcagg ggacaggtgt ccagttgctg ggccgaggga ggagctggtt     5640

tggcatagga cctaaccagt gaagctagag gctacagcca ctaaacttgc ttcaggccaa     5700

cgatagttac tcacaagtaa gtaccttaat gctaatgagg tccactaaaa aggggaggaa     5760

ggcagacctc ctgggagacc cacgaagggt ttttagccag ggaaaactga gccccaggaa     5820

aacctaacca ctgggcaggc agaatttgtt tgagggatag aacgacaaca aaataaatgt     5880

tcctgcagcc tgagatttca ggtagagtac tgactaaggt ttaataagac aataggtgac     5940

ctgaggacat gcaagcttgt aaaatgcaac agcctcctgc tagagtgact tgtacatgag     6000

cttgcttgca gaagactaga ttagatgttt ctcaggatcc cctcctgcgc aggggttctc     6060

tgattttcgt gttctctgcc cagatgggct gggggagttg agagtgtgct tattttcact     6120

gcgatcatga gaccacagtt ctgggttatc tcctctcata catcaagccc cagaggaggc     6180

ggcaagagga acagccacaa acaagtactt taccccacag cttagtggcc agtaaacacc     6240

ctggggacta ggaaaaggaa ccaactgtag gcacctctcc agggcctagg gagacaagtg     6300

tcctctcttc tgcatacatt tgggctcccc ttacagagcc ctttgccctg gctctctggt     6360

ccttgttgct ctaacagtcc agatgtacac ccagcctcag ggggaaggca gctctctcca     6420

gacagagtct cagggcccag caaggtcagg ttatctgctt tcattcaggg caacaaatga     6480

tacaaatggt gccagggagt ggcaaggcca tgggggtagg tgggggtgtc tttttctttt     6540

cataaagtaa caacagacga gactgaggtt aaacatcaga aaaaaacctc tggaatgacc     6600

ttcctcattc caggaggccc tggaataagg aagaggcttc tttctgaggg agctttgagg     6660

aattttgaca gctgttgaca tgggatttgg gaaaggtgaa gctgtgactg gaggggcagg     6720

agatggtcca agtgtccatc cagagatgag actcttagaa tcaaagtgtt cagcccagga     6780

agtcttggag atcccacctt ctgtggccct gcaccttatg ggaagccatt aagggggctc     6840

atctaggaat tctggttaca gcccagtgct catcccagcg tatgctgcct ctttagggca     6900

gccccaaggg ccagccagcc tgtactctgg gcaagagccc aaaatggcta ggaatgtttg     6960

actcccttaa tctcttcccc agctacagag gaatcttttc tctgcctggt ctcagaatgg     7020

gactgccaac tggctcattg gtgggagaca cagtatcctc aaacctgtgg ccactggcat     7080

gacagtggtg ctctgtctcc ctgggtgaca cccaccctag gcttcctcct ggatgtgatg     7140

gggattgcca gagaggctct tagcataaaa ggcattaggt gggcattttt ctgtgtgccc     7200

ccaaaaagct ccatggaaac aggcacctgg tagctgcgga acacccgtgg acttgtgtat     7260

atggtcatag gctttgggaa gacaggacgt aaaggaaaat gagagaaaca aaatgggtca     7320

gatagctttg gccacagccc caggcagcct ttggggccta tgacacttag tgcccttaga     7380

tgggatacat cttgcctcgg ccccaagact cctccaactt acccgtccca tccagggcct     7440

gcacagctta gagaggctca cagcttggca aatgctaggg cttcatcaga ccactgactt     7500

gactcagtgt ttgttaaaat ggaaccactc ccgttggcct actgtttctc tcctgtactt     7560

cttgtaatga tagttattta ttgactctgg tagcaggcag ttcttaaata aagatggttt     7620

ctcaacctgt tggggaagct ggcacgagct gtgggtgtta tcatcaggct                7670


<210>  722
<211>  6975
<212>  DNA
<213>  homo sapiens

<400>  722
aactcgggaa cgggaacagg aggccgttgg aaaactttgg gcaagatggc ccggcggtga       60

tttccgcggc ggtctctcct gcgcccggcc tctgcggcgc aggcccagcc cccgagcctc      120

gcacgttcgg cagccccggc ctggccccgg cccctcctgc ccatggcggt ggccgagctg      180

tacacgcagt acaacagggt ctggattccc gatcctgaag aagtttggaa gtctgctgaa      240

atagccaagg actacagagt tggtgacaag gtcctgcgac tcctgctgga ggatggaacg      300

gagctggatt attctgtcaa tccagaatct ctgcctccac ttcggaatcc tgacatcctc      360

gtgggcgaga atgacctcac ggctctcagc tatcttcacg agcccgcggt gctccacaac      420

ctcagaatcc gctttgcaga atccaaactc atttacacct acagtggaat cattttggtg      480

gccatgaatc cttacaagca gttgccaata tacggagatg ccatcatcca cgcctacagc      540

gggcagaaca tgggcgatat ggacccacac atatttgccg tggcagaaga ggcatacaag      600

cagatggcca gaaacaacag aaaccagtcc ataattgtaa gtggggagtc aggtgctgga      660

aagacagtgt cggctcgcta tgccatgagg tactttgcca ccgtcagcaa atcgggcagc      720

aacgctcacg tggaagacaa ggtcctggca tccaatccca tcaccgaggc cgttggaaat      780

gccaagacca cccgcaatga caatagtagt cggtttggga aatacacaga aatcagtttt      840

gatgaacaaa atcaaattat aggagccaac atgagcactt acctcctgga gaaatccaga      900

gttgtctttc aatcggaaaa tgaacgaaat taccacattt tctatcagct ttgtgcatct      960

gcacagcagt cggaatttaa acatcttaaa ttggggagtg ccgaagaatt taattataca     1020

agaatgggag gcaatactgt cattgagggt gtgaatgatc gagctgaaat ggtagagact     1080

caaaagacct tcacgcttct gggtttcaag gaggattttc agatggacgt ttttaaaatc     1140

ctggcagcca tcctacatct gggcaatgtg cagatcaccg cggtgggcaa cgagaggtcc     1200

tcagttagtg aggatgacag tcacctgaag gtgttctgtg agctcctggg cctggagagt     1260

ggcagagttg ctcagtggct gtgcaatcgc aaaatcgtca caagctctga gacggtggta     1320

aaacccatga ccaggcctca ggctgtcaac gccagggatg cactggccaa aaagatctat     1380

gctcacctgt tcgacttcat tgtggagaga attaaccaag cgttgcagtt ttcaggcaag     1440

cagcacactt ttattggtgt tttggacatt tatggttttg aaacctttga tgtgaacagc     1500

tttgaacaat tttgcatcaa ttacgctaat gaaaaactgc aacaacagtt taacatgcat     1560

gtcttcaaac tggaacaaga agaatacatg aaggaagata taccttggac gctgatagat     1620

ttttatgaca atcaaccagt tattgacctg attgaagcaa aaatgggaat tctggagtta     1680

ctggatgaag aatgtttgtt accacatgga actgatgaaa actggcttca aaagctgtat     1740

aataattttg tcaacaggaa ccctttgttt gaaaagccta gaatgtcaaa cacatccttt     1800

gtcatccagc actttgctga taaggtagag tataaatgtg aaggtttcct ggagaaaaac     1860

agagacaccg tctatgacat gctggttgaa atcctgagag caagcaagtt tcatctctgt     1920

gccaactttt ttcaagaaaa tccaactcct ccttctcctt ttggttcaat gattacagtt     1980

aaatctgcaa agcaagtcat caagccaaac agcaagcatt tccggaccac agttgggagc     2040

aagttccgca gctctctgta cttgctcatg gagaccctca atgcgacgac gccccactac     2100

gttcgatgca tcaagccaaa tgatgagaag ttaccctttg aatttgactc caaaagaatt     2160

gttcagcagc tgcgagcctg cggcgtttta gaaacgattc gcattagtgc acagagctac     2220

ccttccaggt ggacatacat cgagttctac agtcgctacg gcattctcat gaccaagcaa     2280

gagctttcct tcagcgataa aaaggaggtg tgcaaggtgg ttttacacag actcatccag     2340

gattctaatc agtaccagtt tggtaaaacc aaaattttct tcagagcagg acaagtggct     2400

tatttagaga aacttcgatt ggataaactg aggcagagtt gtgttatggt acaaaagcac     2460

atgcgtggct ggctccagag gaaaaaattc ctccgagaga gacgagccgc cctgataatc     2520

cagcagtact tccggggtca gcaaactgtg aggaaagcta ttactgcagt ggccttaaaa     2580

gaagcttggg cagccataat cattcagaag cactgccgcg ggtatcttgt tcgcagcctg     2640

tatcagttga ttcgcatggc caccatcaca atgcaggcct acagccgagg attcctggca     2700

aggaggaggt atcgaaagat gctggaggaa cataaggctg tgatcctaca gaaatacgca     2760

cgggcgtggc tggccagacg cagattccag agtatccgac gattcgtgct taatattcag     2820

cttacttaca gggtccagcg tttgcagaaa aagttggaag atcagaacaa agaaaaccat     2880

gggctggtgg agaagctgac tagcctggct gctcttcgag ctggggatgt ggaaaagatt     2940

cagaagctgg aagcagaact agaaaaagca gccactcaca ggcgaaatta cgaggagaag     3000

gggaagagat acagggatgc tgtggaagag aaattggcaa agcttcagaa gcataattca     3060

gaactggaaa cacagaaaga acaaatacag ctgaagcttc aagagaagac tgaagagtta     3120

aaagaaaaaa tggacaacct caccaagcag ctctttgatg atgtacaaaa ggaagaacgg     3180

caaagaatgc ttcttgaaaa aagttttgaa ctgaaaacac aagactatga gaagcagatt     3240

cagtctttga aagaagaaat taaagctctc aaggatgaga agatgcaact ccaacacctg     3300

gtggaggggg agcacgtcac ttctgatggc ttgaaggcgg aagtggcccg cctgagcaag     3360

caggtcaaga caatctctga gttcgaaaaa gagatagaac tacttcaggc acagaagata     3420

gatgtggaga aacatgtgca gtcacaaaaa cgggaaatga gagaaaagat gtcagagatc     3480

accaaacaac ttctcgaaag ctatgacatt gaagatgtaa gaagcaggct ctctgtggaa     3540

gatctggaac atttaaatga ggatggagaa ctttggtttg cttatgaagg actaaagaaa     3600

gcaacacgtg ttttggagag ccatttccag tctcagaagg attgctatga aaaggagatt     3660

gaagctttga acttcaaagt ggtgcatctc agtcaagaaa tcaaccacct gcagaagtta     3720

ttcagagaag aaaatgacat caatgaaagc atccgtcatg aagttaccag gctaacatca     3780

gagaacatga tgatcccaga ctttaaacag caaatttcag aattggagaa acagaagcaa     3840

gatcttgaaa tccgcctgaa tgaacaagct gagaaaatga aaggaaaact agaagaattg     3900

tctaatcagt tacatcgcag tcaagaggag gaaggaacac aaagaaaggc cttggaagcc     3960

caaaatgaaa tacataccaa agagaaggag aagctgattg ataagattca agaaatgcag     4020

gaggccagtg accacttgaa gaaacaattt gaaactgaaa gtgaagtcaa gtgtaacttc     4080

cggcaggaag catcccggct cactttggaa aacagggatc ttgaagaaga attagacatg     4140

aaagacagag tgattaaaaa gctacaagat caagtcaaga cactaagcaa gacaattgga     4200

aaagccaatg atgtgcactc gtcctcagga cccaaggagt accttggaat gctgcaatac     4260

aagagagaag acgaggccaa gctcattcag aacctcattc ttgacttgaa gccccgtggc     4320

gtggtggtga acatgatccc cgggctgccg gctcatatcc tgttcatgtg tgtgcgctac     4380

gcagactctc tgaatgatgc caacatgctg aagtccctca tgaacagcac cattaatggc     4440

atcaagcagg tggttaagga acatttagaa gactttgaaa tgctgtcctt ttggctttcc     4500

aacacttgtc attttctcaa ttgcctgaag cagtacagcg gagaagagga attcatgaag     4560

cataatagtc cacagcagaa taagaattgc ttgaacaatt ttgacctttc agaatacaga     4620

cagattctca gtgatgtggc tatacgaata tatcatcaat ttattatcat aatggaaaag     4680

aatatccaac cgataatagt tccgggaatg ctggagtatg agagcctgca gggcatttcc     4740

ggcctgaagc ccacaggctt ccggaagcgc tcctctagca tagacgacac ggacggctac     4800

accatgacct ccgtcctgca acagctgagc tacttttaca ccaccatgtg ccagaacggc     4860

ctggaccccg agcttgtgag gcaggcggtg aagcagctct tcttcttgat cggggcggtc     4920

acgctgaaca gcctcttcct gcgcaaggac atgtgctcct gcagaaaagg gatgcagatc     4980

aggtgcaata tcagctactt agaagaatgg cttaaagata agaacttgca gaacagctta     5040

gcaaaggaaa ctttggagcc cctctctcag gcagcctggt tgcttcaggt caagaagacc     5100

acagacagtg atgccaagga gatctacgaa cgctgcacct cactgtctgc tgtgcagatc     5160

ataaagatcc ttaattcata cacacctata gatgactttg agaagagagt gactccatcc     5220

tttgttcgca aagtacaggc tctcctaaat agccgggagg attcatcaca gctgatgttg     5280

gataccaaat atctctttca agtcacattt ccttttaccc cctctccaca tgctctggaa     5340

atgattcaga tccccagcag tttcaagcta ggctttctga ataggttata gcaggagaaa     5400

aagtcaatgc actttttctt caaaagctaa gtgaaggttc aatatgaggg atgtgtttta     5460

ttaattggca gtggaaattg gaatgtgatt taaggaagaa aacagacttt tctcaaatgg     5520

accacatcat ctctcactca cagtgacaat gctgctcctg taattttgta agaattcaca     5580

cacaccagct gtatttggaa aagccatgtc tcactctcga atctcagctg gttttcactg     5640

aaattcctgg agggctcata ttttcttcca cgtgcctctt gatctgttct gtcttgtggc     5700

agggctctac caggagggag tgagatctgg ggacacagtg gcttccaagt tttctaaggt     5760

tcatgtgaaa cctgagtaca tttacaaagc tgcaagtgga ttctagtgct gagtcttcca     5820

ggaaaaaatc ccgtttggcc accgtgacct gccaaaagtt ctcttgcccc atgcctgctg     5880

gggacagaag gttttcatga actcttttta ctgaaaatgc cctgcattta aaaatgttta     5940

ttttagaccc ttctaaattt tttttttttt ttttttttga gactccggag tctcgctcta     6000

tcgccaggct ggagtgtagt ggcatgatct cggcttattg caacctccgc ttcctgggtt     6060

caaacaattc tcctgcctca gcctcctgag tagctgggac tacaggcacc tgccaccacg     6120

cccagctaat ttttgtattt ttagtggaga caggtttcac catgttggcc aggatggcct     6180

cgatctcttg acctcgtgat ccgcccacct cagcctccca aagtgctagg attacaggcg     6240

tgtgccaccg cgcccggctg acccttttaa tttttaagag tgttcaatcc gagatgaatc     6300

atttgaagta tttttatatg tatatctatt taaaactaat atattattaa agcttaattg     6360

ccatgccgtt tatcttctct gaaagaactt caaatcttac ctgccaacat attcaccata     6420

atttttttat tttttaatac ctttcataca ataacttttt taaaacaacc tcagattgaa     6480

aaagcaacct aaattacttt cgctctctaa tcagcatttc aatgtattta tttttaaatt     6540

ttctcaaaaa gtaactaaaa aattgtgtcg gaccctactt ttgagaaatc tacgtttccc     6600

aagttttatg ggaactggct attccttgtc ccggcacacc ttctcattcc ttcctttcag     6660

agcctaaaac ctcatttgat aagcactcct agtctctggc ctgtggatcc agtgctattc     6720

tgtcaccaac ctaagaatcc caattgcacc ttctgtttct gacagtcaca ggtgacagct     6780

gtgattctat aatacagact ggtgtcttag aggtaggaat aatacatgat tatgaagcat     6840

caccctgcta atacataata atgtcttttt atattataag tgattgagtt tagttcattt     6900

caatacattg tacatgaaaa aatgaaaagt agaactttgt aatactttaa tcaataaaat     6960

taattaccaa atgaa                                                      6975


<210>  723
<211>  5999
<212>  DNA
<213>  homo sapiens

<400>  723
agttgccctg tcagtgcagg tggaggcccc ggcggggcaa agtggcagga acctcttaaa       60

gggcgagagc ggcgcggagc cagaacgcgg tcggcccggt ccccgccgca cccagcccag      120

caacatcatg acaacagaga agagtttagt gactgaggcc gaaaattcac agcaccaaca      180

gaaggaagag ggtgaggaag ccataaactc aggccaacaa gaacctcagc aggaggaatc      240

ttgtcaaaca gcagctgaag gagataattg gtgtgaacag aagctgaaag cttctaatgg      300

agacactcct acacatgaag acttgaccaa gaacaaggag cggacatcag aaagcagagg      360

actttcacga ctattctcct cgtttctcaa aaggcccaaa tctcaggtgt ccgaggaaga      420

aggcaaagaa gtagagtcag ataaagaaaa aggtgaagga ggtcagaaag agatagaatt      480

tggaaccagt cttgatgaag agatcatttt aaaggcccca attgcagctc ctgaaccgga      540

actcaaaaca gacccatctt tggatcttca ttcattaagc agtgcagaaa cacagcctca      600

ccattacaat taagaattat tttcagagtc ttcttatttc tgaagcatgt gaatattatc      660

tgcatcgtta aaagtcctgc tcaggaagaa ctcagagaag atccagattt tgaaattaag      720

gaaggagaag gacttgaaga gtgctccaaa atagaagtaa aagaagaaag ccctcaatca      780

aaagcagaaa cagaattaaa agcttcccaa aaaccaatca gaaaacacag gaacatgcac      840

tgcaaggttt ctttgttgga tgacacagtt tatgaatgtg ttgtggagaa acatgctaag      900

ggacaagatt tgcttaaacg agtatgtgag catctcaatc ttttggaaga agactatttt      960

ggtctagcca tttgggataa cgcaacctct aagacatggc tggattccgc caaagaaata     1020

aaaaagcagg ttcgtggtgt cccttggaat tttacattta atgtaaagtt ttatccacct     1080

gacccagcac agttaacaga agacataaca agatattatt tatgtcttca gcttcggcag     1140

gacatagttg caggacgtct gccctgttcc tttgcaacct tagcattatt aggttcttac     1200

accatccagt ctgaactggg agactacgac ccagaactcc atggcgtgga ttatgttagt     1260

gattttaaac tggccccgaa tcagaccaag gaacttgaag agaaggtcat ggaactgcat     1320

aagtcataca ggtccatgac tccagctcag gctgacttgg agtttcttga gaatgccaaa     1380

aagttgtcta tgtatggagt tgatcttcat aaagcaaagg acttggaagg agtagatatc     1440

atcctaggtg tctgctctag tggccttctg gtttacaaag ataagctgag aattaaccgc     1500

ttcccttggc ccaaagtgct gaagatttct tataaacgta gtagcttttt catcaagatt     1560

cggcctggag agcaagagca gtatgaaagt accatcggat tcaaacttcc cagttaccga     1620

gcagctaaga aattatggaa agtctgtgta gaacatcaca cgtttttcag attgacatct     1680

acagacacca ttcccaaaag caaatttctt gcgctaggat ccaaatttcg atacagtggc     1740

cggactcaag ctcagaccag gcaagctagt gctctaattg acaggcctgc cccacacttc     1800

gagcgtacag caagtaaacg ggcgtcccgg agcctcgatg gagcagcagc tgtcgattcg     1860

gcagaccgaa gtcctcggcc cacttctgca cctgccatta ctcagggtca ggttgcagaa     1920

ggtggcgtcc tagatgcctc tgctaaaaaa acagtggtcc ctaaagcaca gaaggaaaca     1980

gtgaaggctg aagtgaaaaa ggaagacgag ccacctgagc aagctgagcc agagcccaca     2040

gaagcatgga aggtggaaaa aacccacatc gaggtgacag tacccacctc aaatggtgac     2100

caaacacaga aaaagagaga aagactagat ggtgaaaaca tttatatcag acatagcaat     2160

ttaatgttgg aggatttaga caagagtcaa gaggagatca aaaaacatca tgccagcatc     2220

agtgagctga aaaagaactt catggagtct gtaccagaac cacggcctag tgaatgggat     2280

aaacgcttat ccactcactc acccttccga actcttaaca tcaatgggca aatccccaca     2340

ggagaaggac ctcccctggt gaagacacaa actgtcacca tctcagataa tgccaatgct     2400

gtgaaaagtg aaatcccaac caaagacgtc cctattgtcc acactgagac caagaccatc     2460

acttatgagg ctgcccagac tgacgacaac agtggagact tggacccagg agtcttgctg     2520

acagctcaaa ctatcacatc tgagacccca agcagcacca ccacaactca aattaccaag     2580

actgtaaaag gtgggatttc agagacacgt attgaaaaga gaattgtgat cacaggagat     2640

gctgatattg accatgatca ggtccttgta caagccatca aggaggcaaa ggagcagcac     2700

ccagacatgt cagtgaccaa ggtggtcgtc caccaggaga ccgagattgc tgatgagtga     2760

gctcaggaac taacctaccc caactctgcc cttctcccat ccaagagaaa ccagcaaaat     2820

gataaagaag ctaacctgcc atagtcagac ttcagacttt caagattatt ctaaatcacc     2880

agaaaattaa tttcagtttc tattgggagt ttataccaag agattcttct agatctcatt     2940

gatccttttg aagagctttt tctatattag gatatcagaa ttgttcaact tttcactcta     3000

tagactgttt taagagtttt ggggtttttt taattgggtg gtttgtaacc ccttcagcct     3060

agcctctctg cccatttatt tccaacccca acagacactg acagggtcca tggaattctt     3120

cgggaaatcc tccaaggact cttgtcagct gtgttggaag ccaaagccag cttagtggga     3180

cttccgcgtc tctccctagt cttatcccct ttggatgatg gcagaaactt catgaaccag     3240

ccctttctca gagccagtga tgtgagtgta tcagaatgcc agggagggca ccagccctga     3300

tccacagacc tcggaaagat gcccctgttc ctttgttgcg ggtggttttg gtaaggcaga     3360

gccctctgct gagaatgtag tattgttttt cccctctccc tcctgctttc tttttggagc     3420

ttctttgggt caaagacatg gaagttgctt cagatatctg atactgtgaa tgtttgaaca     3480

tatccgtggc cttcacctct ccagctaccc ttttacctca tcagaagcag tggctcagct     3540

aagtgctccc cctagctccc atctcaggag accaaatctc acagaaaaat aggcactttg     3600

ggccaaaagc tctaatggaa catttttagt ggtgatttgg ggaaggaaag ttaatgaggt     3660

ttttaaaata aggttttcta gttttgagag tgtgcacttc acacagggga atggggttac     3720

ttctgtctga tcctgggcct ttctttcatc ccaaatgaca aggaatgtgg ctcagagaag     3780

ggtttttctt ttttgacctt tcttctctca acaggaacct gcctgaggac acccttctag     3840

agcaaggaat tgacttttag gagccgttct ccccacaaga caccacatga caaggggtat     3900

aagccccagc cctgctcatt cccactcacc agctgaggtc tgtcaggttt tgaaggcttg     3960

attttgtggt gggtttgggg cttagttttc ctttttttca ttttgatttt tgaaagtgaa     4020

gatgatgccc taattcctgg taaggatttg gggcatagtt ttttgttttt ttgagacgga     4080

gtttcgctct tgttgcccaa gctggagtgc agtggcgcga tctcggctca ctgcaacctc     4140

cgcctcctgg gttcaagcag ttctcttgcc tcagcctccc aagtagctgg gatgacaggc     4200

gcacaccacc acgcccagca aattttttgt atttttagta gaaacgggat ttcaccttgt     4260

taggctggtc tcgaactcct gacctcaggt gatccaccca ccttggcctc ccaaagtgct     4320

gggattacag gtgtgagcca ccacgcccgg ccgatttggg gcatttttat ttaacagaac     4380

ttctctaacc ttccaactgc ttcccacaaa cacattggcc tcaaggctcc ttagaatccc     4440

agttccagct tcctaaaata gacagtgggt atcgggcagc agtcactggg gctcaagggc     4500

agtgagcaag agaaatgtct aaagctgctt ctcccaacac cgtccaaagt ctccactgcc     4560

tgagttttgt ttcggctggt ttgaactcat ttcgggtgtg tgcatttttc ttttggtacc     4620

catgtgagac atgaacaaca ggagggaggg aaagagccca ggtgggacgt gggacaggct     4680

taggggaaag agcttgtcct atctcaggaa caaaattata ggctgtgggc agagggtctg     4740

aaaggtgggc tttggggtag tgcccaagcc tggtcgtgtt gccaggagtg gtgacaagaa     4800

atgcagctta catcaaacga acatgtagtg catgcccact gcctgatggc cagatggcct     4860

gtaggaagag ctaccagggc ttccagacct gtggaacgaa gaggatgggg aaaaggcaga     4920

gggcactgag tgtcccttta aaaactaacc cactgaatat tccgtgtgat ctagaacagt     4980

gtggcagctt tcacagcaca ggaccgttca tcgggggcct aaacgtttcc ctcagctctg     5040

tcaccaactc acttctctcg gcttcgttgt ctgtaaattg gatgaaaaga gctctaatgc     5100

ctttcaggct cttagaagcc atagatttgg acaagcccag caagatgggt gtccttccag     5160

gcctcttccc ctttcctcca tctctggcaa cagttcttgg ggtttggcaa ttgtttggat     5220

tttttttctt tctgcagttg tgtgtatgtg tgtttgtgtg aagaaaaaca gactctgtcc     5280

aggtagaaat ggtgaggagg gggaagagaa ttacatttcc agggtcagaa acttggcaac     5340

agttttccta gagtgactca gacacaccac agtaacaact ctcgctgcaa ttttatttta     5400

atttgagaaa taaagatttc ctccaagcca catgaggact ctggcaccca cccacaaagc     5460

aagacctgta tttataagcc gagggctcag ggagcctaac tgcgggaccc gtcagggccc     5520

cgtgacccat ccccgtcccc acccccccct ccaccgctgg gcccatcagt gtgtgttggg     5580

gggatgcttg gcagctgggg gtgaggagac aacaaacctc gggaactgga gccagagctg     5640

cggcctgact gacgcctttt gatgctcacg ggaaatttct gcccaggatc tcagccccag     5700

gctggttgtt tctacaaatc tctctcaaat gtattatttt ggtgacaaaa atgaaggagc     5760

tttgtaaatt ttttttaaaa ttatgaatca tatcaagtag ttgtttacat ttcttgaaaa     5820

aataggaact cgggcagcag aatcagattg gcagaatctt tagactacac aggcaataat     5880

caagtctgct gttttggcct ttcgtagtag aagtggttgt agtgtttaga tatctgtttg     5940

gtcttgcttc ttgtattgca tttttttcaa taaacaacaa caaaaagaac tctcaaaaa      5999


<210>  724
<211>  2234
<212>  DNA
<213>  homo sapiens

<400>  724
ggcgcgggcg cgggcggggg cggagtggcg gcggcagcgg cggctagaag cggcagccca       60

gagccctctc gcggccgcgg cggcagcagc agcgccagcc ccagcaacac tgaggccgcc      120

gccgccgcct ggcgctcccg ccgcccggcc cgacatgagt gaggcggttc gggtaccctc      180

gcccgccact ccgctggtgg tggcggcggc cgcgcctgag gagaggaaag ggaaggagtc      240

agagcgcgag aagctgccgc ccatcgtatc ggcgggcgcc ggcgcgaccg cgggtttgga      300

cagaggagcc aaaggccaaa tttccacttt cagcagtttt atttcagctg ttagcccgaa      360

gaaagaagct gctgaaaaca gaagttcacc tgcacatctt gttttcccta acatcaagaa      420

tgtgagagaa ccaccaccaa tttgccttga tgttagacaa aaacagcgta catctatgga      480

tgcatcatca tccgaaatga aggccccagt ccttccagaa cctattcttc ctatccagcc      540

caaaactgtg aaagactttc aggaagatgt agaaaaagtt aagtcatcag gagattggaa      600

agcagtacat gatttttatc taacaacgtt tgattctttc ccagaattaa atgctgcatt      660

taagaaagat gccactgcct catttaacac cattgaagac tctgggatta atgctaaatt      720

tgtgaatgct gtgtatgata ccttacttaa tactgtaagt attatgacat gcaagtaata      780

ttattctgtg tctcttctgt atatcaaaag cagccataca aatattgtaa aaatcacctt      840

ataattacct tagaaactct gatacaattt tatagtaaat gtagctggaa ttctcataaa      900

gttagattat tttattcttt tattttttaa ttatgaatta agcagcaaat acttttatat      960

ccaatccttt tttagaaaga cttgctaaaa tcatgcttta cttactcagc aaaaggaggt     1020

aagttattta attatattgg aattacactg aatctgtaga tcagtggttc ttaaacatta     1080

gcctgtatca gaatcacaag aagggcttgt taaaatacag aatttcagat tcagtaggtc     1140

ttgggtgaag cccaagaatt ttcatttgta acaagttccc aggatatgtt gatttatgag     1200

ttcatttatg atgtgacaca tactataaaa attatgtcac cattcaaaaa atccagatgc     1260

atatttgaag gactaagtgg gaatgataaa gacagaatgt aaacaaagtc tccagaagtt     1320

tagctatgaa gtgaaagaca tgttaagaat gaccacattt tgagaaccat actgctatag     1380

atcaatttgt gaaaaattga catcttttca atccataagc atactgtatc cttttaggta     1440

cctaggtctt ctttaatttc tcttggtaat gttttgtagt tttctggata gaggtgttac     1500

acatttctca ttacatgtat ttctaggtac ttcatttttt ttatcctatt ataattttat     1560

tttccaattg tgactaatat atggaaatac tttcatatat ttatctttat ctaaatacag     1620

ttgacccttg aacaatgcga gggttagggg cgctaacccc ctatgcagta aaaaaaaaaa     1680

tctgtgtata acttttgact ccccagaagc ttaactacta ataacctatt gttgaccaga     1740

agtcttactg ataacataaa cagtcaatta acgtatattt tatgttatat gtattctata     1800

ctatattgtt acaataaagt aagctaagga aaaggcaatg ttattaagaa aaaataagga     1860

agataaaata tatttactat atattaagtg gaagtggact atcataaagg tcttcatcct     1920

tattgagtag gctgaggaag aggaggggtt ggtcttgctg tctcaggtgg cagaggtgaa     1980

agaaaataat gtatataagc agacttgcac aattcaagcc tgtattcaag agtcaactgt     2040

actttgctat attcatccat taattctaat agtacatcag taaattaact tggattttct     2100

gtgtacacaa tcttgtcatt tgtgaaaaag gagagtttta tctccttcta atcctgtatc     2160

ttatatggat atatgtatgt gtttgcattg actgggacct ctttcacaat tgtgaataaa     2220

agaagtaata gcag                                                       2234


<210>  725
<211>  2932
<212>  DNA
<213>  homo sapiens

<400>  725
aaaggggccc cagacaatcc tcgcaataac aacaaaaccg gcgcgccagc ggtggcgcaa       60

cggctctcgt ccccgccctc ctgctacctg tagtcgcctg ggccgccccc ggcccagccc      120

tgccttgccg ccaccctgcg ctgtccagac tgaggggtca ggcggagagc cgggccgcgc      180

cttcggtcag cttctctccc tttcacccgc gcctcctcgc gagacccggg gctgggccgt      240

gccggtcgcc gcgcagcagg aagggagcgg ctgccacgga aaacgcctgg ccggacggtg      300

tggctggcgg ccctgcctgg gcgcggaggg cggcggtggc gggccccgcg gccttctctc      360

agcttccttt ctcctcacga cggcctccac agtccggagc ccggcggagc ccggacctgg      420

cggggagagc tgcctccacg gccgggcacc cagaccccac cgtcgcagtc gccaccacct      480

cagtccatcc ttggtaccgg caatgggctt cgtatcctcc agtgcacttg taactgactt      540

ggacacggaa tactaagaac tcacttctgt cctcatccca gtcgcgccgg cggtgaccat      600

ctcggctctt ttgggcttaa ctgccgctcc tctggactct gtctgacttt gggggcacca      660

tggaccaaag tgggatggag attcctgtga ccctcatcat taaagcaccg aatcagaaat      720

acagtgacca gactattagc tgcttcttga actggaccgt ggggaaacta aaaacgcatc      780

tatctaacgt ttaccctagc aaaccattga cgaaggatca gagattggtg tattcgggca      840

gactgcttcc cgatcatctg cagctgaaag acattctcag aaaacaagat gagtatcata      900

tggttcatct agtatgtact tctcggactc ctcccagttc tccaaaatcc agcaccaata      960

gagaaagtca tgaagcattg gcatccagca gcaattctag ttcagatcat tcaggatcaa     1020

caactccatc atctggtcaa gaaaccttgt ctttagctgt gggttcttcc tcagaaggat     1080

tgaggcagcg tacccttcca caagcacaaa ctgaccaagc acagagtcac cagtttccat     1140

atgtaatgca aggaaatgta gacaaccaat ttcctgggca agctgctcca cctggattcc     1200

cagtgtatcc cgcgtttagc ccactgcaga tgctatggtg gcaacagatg tatgctcatc     1260

agtattatat gcagtatcaa gctgcagttt cagctcaggc cacatcaaat gtcaacccaa     1320

cccagcctac tacttcacag cctctaaatt tggcacatgt tcctggagaa gaacccccac     1380

cagctccaaa cctagtggcc caagaaaatc gacccatgaa tgagaatgtt caaatgaatg     1440

cacagggagg tccagtacta aatgaagaag acttcaatcg agactggcta gactggatgt     1500

acacgttctc acgagctgcg attctcctta gcattgtata cttctattct tcttttagtc     1560

ggtttatcat ggtaatggga gccatgctac tggtttattt acaccaagct ggatggtttc     1620

cttttaggca agaaggaggt catcagcagg ctcccaacaa taatgccgaa gttaacaatg     1680

atgggcaaaa tgcaaacaac ttggaacttg aagaaatgga gcgtcttatg gatgatgggc     1740

ttgaagatga gagtggagaa gatggaggtg aagatgccag tgcaattcaa aggcctggat     1800

taatggcttc agcttggtct ttcatcacca ccttctttac ttcactaata ccagaggggc     1860

ctccccaggt tgccaattga cctgaaaaac tgtgccagct acaaggaggg tctgacttca     1920

ggaaagtggt ttaaataaca gtgcaatttc aaaaaaattt ataactttct tttgatcatc     1980

atgtacagag gtgttttttt tctttaggct tctcatgcat atgaatattt taagcacgaa     2040

tggactacta aatatctgag tttttttttt ttttttttaa agatcctaac agaacatagc     2100

gtaacaatat tggtcttcca ggtgttactc atttcaatta tgtgtagtat accaggacag     2160

acctattttc atgtcttatt tctttaaaga gctgcttcat tggccgggcg ccatggctca     2220

cgtctgtaat cccagcactt tgggaggccg aggcgggtgg gttacttgag gtcaggagtt     2280

cgagaccagc ctggcaaaca tggcgaaacc ccatcttaac taaaaataca aaaaaattag     2340

ccgggtgtgg tgtcacgcgc ctgtaatccc agctacttgg ggggctcagg caggagaatt     2400

gcctgaaccc aggaggcgga ggttgcagtg agctgagatt gggccactgc actccaccct     2460

gggcgacaga gtgagactcg gtctcagaaa aaaaaaaaaa agagctgctt cacatataaa     2520

tgtctatagc tagtagcctg gccctttaat gtttaatttg aatagatata tctgttttcc     2580

gtgaattatc ttgaaagttt taaacagaat gacctcatag tttttaataa agaatattat     2640

ttacctaaaa tgtgctagta gcatcttgcc cagccataaa gcaataaact tctcaataat     2700

cttaattttg atatttgaat aaataatgga aactttctgt attaagggca tgtatcccat     2760

caattggaat cagtacctta acagaaaaag gcagctcttc aatggaatta acgtgatata     2820

aaatgtttga tataggcagt acttttataa aaaaagataa gctggaaatt gctccgtgta     2880

attttttaaa taaaaagtca attatggtaa aaaaaaaaaa aaaaaaaaaa aa             2932


<210>  726
<211>  2932
<212>  DNA
<213>  homo sapiens

<400>  726
aaaggggccc cagacaatcc tcgcaataac aacaaaaccg gcgcgccagc ggtggcgcaa       60

cggctctcgt ccccgccctc ctgctacctg tagtcgcctg ggccgccccc ggcccagccc      120

tgccttgccg ccaccctgcg ctgtccagac tgaggggtca ggcggagagc cgggccgcgc      180

cttcggtcag cttctctccc tttcacccgc gcctcctcgc gagacccggg gctgggccgt      240

gccggtcgcc gcgcagcagg aagggagcgg ctgccacgga aaacgcctgg ccggacggtg      300

tggctggcgg ccctgcctgg gcgcggaggg cggcggtggc gggccccgcg gccttctctc      360

agcttccttt ctcctcacga cggcctccac agtccggagc ccggcggagc ccggacctgg      420

cggggagagc tgcctccacg gccgggcacc cagaccccac cgtcgcagtc gccaccacct      480

cagtccatcc ttggtaccgg caatgggctt cgtatcctcc agtgcacttg taactgactt      540

ggacacggaa tactaagaac tcacttctgt cctcatccca gtcgcgccgg cggtgaccat      600

ctcggctctt ttgggcttaa ctgccgctcc tctggactct gtctgacttt gggggcacca      660

tggaccaaag tgggatggag attcctgtga ccctcatcat taaagcaccg aatcagaaat      720

acagtgacca gactattagc tgcttcttga actggaccgt ggggaaacta aaaacgcatc      780

tatctaacgt ttaccctagc aaaccattga cgaaggatca gagattggtg tattcgggca      840

gactgcttcc cgatcatctg cagctgaaag acattctcag aaaacaagat gagtatcata      900

tggttcatct agtatgtact tctcggactc ctcccagttc tccaaaatcc agcaccaata      960

gagaaagtca tgaagcattg gcatccagca gcaattctag ttcagatcat tcaggatcaa     1020

caactccatc atctggtcaa gaaaccttgt ctttagctgt gggttcttcc tcagaaggat     1080

tgaggcagcg tacccttcca caagcacaaa ctgaccaagc acagagtcac cagtttccat     1140

atgtaatgca aggaaatgta gacaaccaat ttcctgggca agctgctcca cctggattcc     1200

cagtgtatcc cgcgtttagc ccactgcaga tgctatggtg gcaacagatg tatgctcatc     1260

agtattatat gcagtatcaa gctgcagttt cagctcaggc cacatcaaat gtcaacccaa     1320

cccagcctac tacttcacag cctctaaatt tggcacatgt tcctggagaa gaacccccac     1380

cagctccaaa cctagtggcc caagaaaatc gacccatgaa tgagaatgtt caaatgaatg     1440

cacagggagg tccagtacta aatgaagaag acttcaatcg agactggcta gactggatgt     1500

acacgttctc acgagctgcg attctcctta gcattgtata cttctattct tcttttagtc     1560

ggtttatcat ggtaatggga gccatgctac tggtttattt acaccaagct ggatggtttc     1620

cttttaggca agaaggaggt catcagcagg ctcccaacaa taatgccgaa gttaacaatg     1680

atgggcaaaa tgcaaacaac ttggaacttg aagaaatgga gcgtcttatg gatgatgggc     1740

ttgaagatga gagtggagaa gatggaggtg aagatgccag tgcaattcaa aggcctggat     1800

taatggcttc agcttggtct ttcatcacca ccttctttac ttcactaata ccagaggggc     1860

ctccccaggt tgccaattga cctgaaaaac tgtgccagct acaaggaggg tctgacttca     1920

ggaaagtggt ttaaataaca gtgcaatttc aaaaaaattt ataactttct tttgatcatc     1980

atgtacagag gtgttttttt tctttaggct tctcatgcat atgaatattt taagcacgaa     2040

tggactacta aatatctgag tttttttttt ttttttttaa agatcctaac agaacatagc     2100

gtaacaatat tggtcttcca ggtgttactc atttcaatta tgtgtagtat accaggacag     2160

acctattttc atgtcttatt tctttaaaga gctgcttcat tggccgggcg ccatggctca     2220

cgtctgtaat cccagcactt tgggaggccg aggcgggtgg gttacttgag gtcaggagtt     2280

cgagaccagc ctggcaaaca tggcgaaacc ccatcttaac taaaaataca aaaaaattag     2340

ccgggtgtgg tgtcacgcgc ctgtaatccc agctacttgg ggggctcagg caggagaatt     2400

gcctgaaccc aggaggcgga ggttgcagtg agctgagatt gggccactgc actccaccct     2460

gggcgacaga gtgagactcg gtctcagaaa aaaaaaaaaa agagctgctt cacatataaa     2520

tgtctatagc tagtagcctg gccctttaat gtttaatttg aatagatata tctgttttcc     2580

gtgaattatc ttgaaagttt taaacagaat gacctcatag tttttaataa agaatattat     2640

ttacctaaaa tgtgctagta gcatcttgcc cagccataaa gcaataaact tctcaataat     2700

cttaattttg atatttgaat aaataatgga aactttctgt attaagggca tgtatcccat     2760

caattggaat cagtacctta acagaaaaag gcagctcttc aatggaatta acgtgatata     2820

aaatgtttga tataggcagt acttttataa aaaaagataa gctggaaatt gctccgtgta     2880

attttttaaa taaaaagtca attatggtaa aaaaaaaaaa aaaaaaaaaa aa             2932


<210>  727
<211>  1475
<212>  DNA
<213>  homo sapiens

<400>  727
gggatcacac aggatccgga gctggtgctg ataacagcgg aatcccccgt ctacctctct       60

ccttggtcct ggaacagcgc tactgatcac caagtagcca caaaatataa taaaccctca      120

gcacttgctc agtagttttg tgaaagtctc aagtaaaaga gacacaaaca aaaaattctt      180

tttcgtgaag aactccaaaa ataaaattct ctagagataa aaaaaaaaaa aaaaggaaaa      240

tgccagctga tataatggag aaaaattcct cgtccccggt ggctgctacc ccagccagtg      300

tcaacacgac accggataaa ccaaagacag catctgagca cagaaagtca tcaaagccta      360

ttatggagaa aagacgaaga gcaagaataa atgaaagtct gagccagctg aaaacactga      420

ttttggatgc tctgaagaaa gatagctcgc ggcattccaa gctggagaag gcggacattc      480

tggaaatgac agtgaagcac ctccggaacc tgcagcgggc gcagatgacg gctgcgctga      540

gcacagaccc aagtgtgctg gggaagtacc gagccggctt cagcgagtgc atgaacgagg      600

tgacccgctt cctgtccacg tgcgagggcg ttaataccga ggtgcgcact cggctgctcg      660

gccacctggc caactgcatg acccagatca atgccatgac ctaccccggg cagccgcacc      720

ccgccttgca ggcgccgcca ccgcccccac cgggacccgg cggcccccag cacgcgccgt      780

tcgcgccgcc gccgccactc gtgcccatcc ccgggggcgc ggcgccccct cccggcggcg      840

ccccctgcaa gctgggcagc caggctggag aggcggctaa ggtgtttgga ggcttccagg      900

tggtaccggc tcccgatggc cagtttgctt tcctcattcc caacggggcc ttcgcgcaca      960

gcggccctgt catccccgtc tacaccagca acagcggcac ctccgtgggc cccaacgcag     1020

tgtcaccttc cagcggcccc tcgcttacgg cggactccat gtggaggccg tggcggaact     1080

gagggggctc aggccacccc tcctcctaaa ctccccaacc cacctctctt ccctccggac     1140

tctaaacagg aacttgaata ctgggagaga agaggacttt tttgattaag tggttacttt     1200

gtgttttttt aatttctaag aagttacttt ttgtagagag agctgtatta agtgactgac     1260

catgcactat atttgtatat attttatatg ttcatattgg attgcgcctt tgtattataa     1320

aagctcagat gacatttcgt tttttacacg agatttcttt tttatgtgat gccaaagatg     1380

tttgaaaatg ctcttaaaat atcttccttt ggggaagttt atttgagaaa atataataaa     1440

agaaaaaagt aaaggctttt aaaaaaaaaa aaaaa                                1475


<210>  728
<211>  1475
<212>  DNA
<213>  homo sapiens

<400>  728
gggatcacac aggatccgga gctggtgctg ataacagcgg aatcccccgt ctacctctct       60

ccttggtcct ggaacagcgc tactgatcac caagtagcca caaaatataa taaaccctca      120

gcacttgctc agtagttttg tgaaagtctc aagtaaaaga gacacaaaca aaaaattctt      180

tttcgtgaag aactccaaaa ataaaattct ctagagataa aaaaaaaaaa aaaaggaaaa      240

tgccagctga tataatggag aaaaattcct cgtccccggt ggctgctacc ccagccagtg      300

tcaacacgac accggataaa ccaaagacag catctgagca cagaaagtca tcaaagccta      360

ttatggagaa aagacgaaga gcaagaataa atgaaagtct gagccagctg aaaacactga      420

ttttggatgc tctgaagaaa gatagctcgc ggcattccaa gctggagaag gcggacattc      480

tggaaatgac agtgaagcac ctccggaacc tgcagcgggc gcagatgacg gctgcgctga      540

gcacagaccc aagtgtgctg gggaagtacc gagccggctt cagcgagtgc atgaacgagg      600

tgacccgctt cctgtccacg tgcgagggcg ttaataccga ggtgcgcact cggctgctcg      660

gccacctggc caactgcatg acccagatca atgccatgac ctaccccggg cagccgcacc      720

ccgccttgca ggcgccgcca ccgcccccac cgggacccgg cggcccccag cacgcgccgt      780

tcgcgccgcc gccgccactc gtgcccatcc ccgggggcgc ggcgccccct cccggcggcg      840

ccccctgcaa gctgggcagc caggctggag aggcggctaa ggtgtttgga ggcttccagg      900

tggtaccggc tcccgatggc cagtttgctt tcctcattcc caacggggcc ttcgcgcaca      960

gcggccctgt catccccgtc tacaccagca acagcggcac ctccgtgggc cccaacgcag     1020

tgtcaccttc cagcggcccc tcgcttacgg cggactccat gtggaggccg tggcggaact     1080

gagggggctc aggccacccc tcctcctaaa ctccccaacc cacctctctt ccctccggac     1140

tctaaacagg aacttgaata ctgggagaga agaggacttt tttgattaag tggttacttt     1200

gtgttttttt aatttctaag aagttacttt ttgtagagag agctgtatta agtgactgac     1260

catgcactat atttgtatat attttatatg ttcatattgg attgcgcctt tgtattataa     1320

aagctcagat gacatttcgt tttttacacg agatttcttt tttatgtgat gccaaagatg     1380

tttgaaaatg ctcttaaaat atcttccttt ggggaagttt atttgagaaa atataataaa     1440

agaaaaaagt aaaggctttt aaaaaaaaaa aaaaa                                1475


<210>  729
<211>  2262
<212>  DNA
<213>  homo sapiens

<400>  729
ctggggagta atagcatggg caaccattat cctgtctcgc cgccacccag gacatggctt       60

ctgttccaat gccaagtgag tacacctatg tgaaactgag aagtgattgc tcgaggcctt      120

ccctgcaatg gtacacccga gctcaaagca agatgagaag gcccagcttg ttattaaaag      180

acatcctcaa atgtacattg cttgtgtttg gagtgtggat cctttatatc ctcaagttaa      240

attatactac tgaagaatgt gacatgaaaa aaatgcatta tgtggaccct gaccatgtaa      300

agagagctca gaaatatgct cagcaagtct tgcagaagga atgtcgtccc aagtttgcca      360

agacatcaat ggcgctgtta tttgagcaca ggtatagcgt ggacttactc ccttttgtgc      420

agaaggcccc caaagacagt gaagctgagt ccaagtacga tcctcctttt gggttccgga      480

agttctccag taaagtccag accctcttgg aactcttgcc agagcacgac ctccctgaac      540

acttgaaagc caagacctgt cggcgctgtg tggttattgg aagcggagga atactgcacg      600

gattagaact gggccacacc ctgaaccagt tcgatgttgt gataaggtta aacagtgcac      660

cagttgaggg atattcagaa catgttggaa ataaaactac tataaggatg acttatccag      720

agggcgcacc actgtctgac cttgaatatt attccaatga cttatttgtt gctgttttat      780

ttaagagtgt tgatttcaac tggcttcaag caatggtaaa aaaggaaacc ctgccattct      840

gggtacgact cttcttttgg aagcaggtgg cagaaaaaat cccactgcag ccaaaacatt      900

tcaggatttt gaatccagtt atcatcaaag agactgcctt tgacatcctt cagtactcag      960

agcctcagtc aaggttctgg ggccgagata agaacgtccc cacaatcggt gtcattgccg     1020

ttgtcttagc cacacatctg tgcgatgaag tcagtttggc gggttttgga tatgacctca     1080

atcaacccag aacacctttg cactacttcg acagtcaatg catggctgct atgaactttc     1140

agaccatgca taatgtgaca acggaaacca agttcctctt aaagctggtc aaagagggag     1200

tggtgaaaga tctcagtgga ggcattgatc gtgaattttg aacacagaaa acctcagttg     1260

aaaatgcaac tctaactctg agagctgttt ttgacagcct tcttgatgta tttctccatc     1320

ctgcagatac tttgaagtgc agctcatgtt tttaactttt aatttaaaaa cacaaaaaaa     1380

attttagctc ttcccacttt ttttttccta tttatttgag gtcagtgttt gtttttgcac     1440

accattttgt aaatgaaact taagaattga attggaaaga cttctcaaag agaattgtat     1500

gtaacgatgt tgtattgatt tttaagaaag taatttaatt tgtaaaactt ctgctcgttt     1560

acactgcaca ttgaatacag gtaactaatt ggaaggagag gggaggtcac tcttttgatg     1620

gtggccctga acctcattct ggttccctgc tgcgctgctt ggtgtgaccc acggaggatc     1680

cactcccagg atgacgtgct ccgtagctct gctgctgata ctgggtctgc gatgcagcgg     1740

cgtgaggcct gggctggttg gagaaggtca caacccttct ctgttggtct gccttctgct     1800

gaaagactcg agaaccaacc agggaagctg tcctggaggt ccctggtcgg agagggacat     1860

agaatctgtg acctctgaca actgtgaagc caccctgggc tacagaaacc acagtcttcc     1920

cagcaattat tacaattctt gaattccttg gggatttttt actgcccttt caaagcactt     1980

aagtgttaga tctaacgtgt tccagtgtct gtctgaggtg acttaaaaaa tcagaacaaa     2040

acttctatta tccagagtca tgggagagta caccctttcc aggaataatg ttttgggaaa     2100

cactgaaatg aaatcttccc agtattataa attgtgtatt taaaaaaaag aaacttttct     2160

gaatgcctac ctggcggtgt ataccaggca gtgtgccagt ttaaaaagat gaaaaagaat     2220

aaaaactttt gaggaaaaaa aaaaaaaaaa aaaaaaaaaa aa                        2262


<210>  730
<211>  4295
<212>  DNA
<213>  homo sapiens

<400>  730
gaggaggttc ctgtagggcg gcacaaccag ggagggcgtg gaagctctgc atcccttctc       60

ccataccttg ctctacacat ctcttcatct gtatcctctg cagcatcctt gatgataaac      120

cagtaaatat gagttttgat catcctgaga aaaatgggcc ttggcctgca gacccaataa      180

accttccctc ccatggataa tagtgctaat tcctgaggac ctgaagggcc tgccgcccct      240

gggggattag ccagaagcag gcttgttttc ctgctcagaa caaagtgact tccctgaaca      300

catcttcatt atgattcaca ccaacctgaa gaaaaagttc agctgctgcg tcctggtctt      360

tcttctgttt gcagtcatct gtgtgtggaa ggaaaagaag aaagggagtt actatgattc      420

ctttaaattg caaaccaagg aattccaggt gttaaagagt ctggggaaat tggccatggg      480

gtctgattcc cagtctgtat cctcaagcag cacccaggac ccccacaggg gccgccagac      540

cctcggcagt ctcagaggcc tagccaaggc caaaccagag gcctccttcc aggtgtggaa      600

caaggacagc tcttccaaaa accttatccc taggctgcaa aagatctgga agaattacct      660

aagcatgaac aagtacaaag tgtcctacaa ggggccagga ccaggcatca agttcagtgc      720

agaggccctg cgctgccacc tccgggacca tgtgaatgta tccatggtag aggtcacaga      780

ttttcccttc aatacctctg aatgggaggg ttatctgccc aaggagagca ttaggaccaa      840

ggctgggcct tggggcaggt gtgctgttgt gtcgtcagcg ggatctctga agtcctccca      900

actaggcaga gaaatcgatg atcatgacgc agtcctgagg tttaatgggg cacccacagc      960

caacttccaa caagatgtgg gcacaaaaac taccattcgc ctgatgaact ctcagttggt     1020

taccacagag aagcgcttcc tcaaagacag tttgtacaat gaaggaatcc taattgtatg     1080

ggacccatct gtataccact cagatatccc aaagtggtac cagaatccgg attataattt     1140

ctttaacaac tacaagactt atcgtaagct gcaccccaat cagccctttt acatcctcaa     1200

gccccagatg ccttgggagc tatgggacat tcttcaagaa atctccccag aagagattca     1260

gccaaacccc ccatcctctg ggatgcttgg tatcatcatc atgatgacgc tgtgtgacca     1320

ggtggatatt tatgagttcc tcccatccaa gcgcaagact gacgtgtgct actactacca     1380

gaagttcttc gatagtgcct gcacgatggg tgcctaccac ccgctgctct atgagaagaa     1440

tttggtgaag catctcaacc agggcacaga tgaggacatc tacctgcttg gaaaagccac     1500

actgcctggc ttccggacca ttcactgcta agcacaggct cctcactctt ctccatcagg     1560

cattaaatga atggtctctt ggccacccca gcctgggaag aacattttcc tgaacaattc     1620

cagcctgctc cttttactct aggggcctct gtcagcaaga ccatggggac ttcaagagcc     1680

tgtggtcagg aaatcaggtc cagccttccc tgtagccaga cagtttatga gcccagagcc     1740

tcctgccaca cacatgcaca catatctagc attctttcca gacagcatcc tccccgcctt     1800

ccaccttggt agatgcaagg tctatctctc ccatcagggc tgccaaagct gggctttgtt     1860

tttcccagca gaatgatgcc attctcacaa accaatgctc tatattgctt gaagtctgca     1920

tctaaatatt gatttcacgt tttaaagaaa ttctcttaaa ttacaattgt gcccaatgca     1980

gggtggctct ggggggcaag taggtggtac aggggattgg aaacatgctc cgcgcctcca     2040

gagaaaagtt gctcccgagg tccatgcccc tggaacgtgt tcctatcact ctggctggtt     2100

gggctggtcc ttagactggg tgcttatgat taaagggtct tggttagccc actttccctc     2160

tccatgtgga gatggaaggt agagaaggat acagtgtcta tcctcaagtt gctacggttc     2220

agtgagagag gcagacatct gaacaggcag gtaggattca gtgtgctcag tgcactgggg     2280

atttggagag agatgggctt gctctctctg tgcacccagg agggccacgc acttaaaact     2340

gtgtttgtgg atcagagaag gctttatagc acagggggca ttcagatgag tcttagagga     2400

agagaagaaa catggcaagc agattacatc tgagccgttt gaattgtgtt tttctttctt     2460

cccatgttta ttttctaaga tctacctgaa cttagagact caagatattt ttttaggaaa     2520

cctcctaccc atgtctgagg tagcaagtgc agcctcacga cagataccag gcaatccaga     2580

gccacaaaac gtgattcctc caggctctgc ctggcctgac cctgtcctgt cagctgggtt     2640

tacataccag tcccattctt ccttttcaat acctaccccc aaatcttctc ctaaccacca     2700

tctgtttttt ttttttaaag cattttttgc tttaaaagca tcctgacccc aatttctttg     2760

agctcacggg ccttttgctg aaggtctctc agggtgtagt ggtgtggctc tctggactta     2820

acgtcactct cagaggtcag aaccttggag atcagaactg attctcacca ggtgtgagag     2880

gtgtggtagc agattgcaat gctctgcacc tcttccttgc aagtgagcaa cttcaggctc     2940

tctgggcaga ggctggccca ctgtagtttg cagacatgct ctccagatgg ttttactaag     3000

tcccctctcc ctgataggga atcctgctgg accagcgcag ccctggtgtg gagaggttaa     3060

aagacttgca caggatcacc aagtcatgct gtagagccag gattcctaga cccagggctc     3120

tgcactctca aggctggccc catgtgctca aggggatcta atgtttgggc tccaaactaa     3180

ccatctcgga gctgggctcc tcatttactg ccaaaccctc agcttatgta gctagaaagg     3240

gccctggagt gagaaagcct ggattttcaa attgatgctc ccctactgac tagctgtgcc     3300

actctgggca aatgctcttc cttgagcctg tttccacacc tgtaaagtgg ggatgatgat     3360

cctatctcac tgcttttgtg aggattacag gaaagcacct gtcctggctc tgtacctggc     3420

acgtagtagg tgctcagttc atgctggttt ccttcctgcc tttagtaggg acctgctctg     3480

tgctcacacc tcggctgcat gcaccctgct gtgacggagg ctagtgtgga agaggtcctg     3540

tcctcaggga attaactgtc ttattgggag acaacaactg tcctccttgg aacacccaag     3600

aaaccatgca aagcagtgga caacacagaa cacgccctcc tcctcgctgc ctgcagctcc     3660

aatctgattc tgcttgggaa tgggcggagc acgtgggctg cttaactgct gtataggaca     3720

agccccttac ccctctctgg gcccatgaat tcctggcttg gtttatgttc tgatttgaca     3780

cactgatttt aatcttcgaa tcatgacact gagtgcagag gaggtggcat tccgacagca     3840

ggacatacat gttggtgtga agactgggac gacactgggt agaatctagt ttttaattat     3900

tattaatata aaggatcaaa ttaatttaaa tatgattctg aagtctacag aacttttagt     3960

tctgtgctgt ctatgtggac actttggtaa aatgcaaatt atgatatgga cgttatcatt     4020

ggtctggtga gatgtttcat atttgtgaca gttaatttaa aaattatgag ttaatgctgc     4080

ctgtgtctat ggggttctgt cttctttgat agccatctat tcatctggat catgggaccc     4140

tctctaatcc ttccaccaat caaataagct attgctattg gtttggagtt gagatatcag     4200

tctcggaaac ttctgaaaaa tgctaataat tacccaagga ttatgtcaaa ttttaaaata     4260

aatgtgtgtg tgtttcttta aaaaaaaaaa aaaaa                                4295


<210>  731
<211>  2685
<212>  DNA
<213>  homo sapiens

<400>  731
tcccgcccgc gccctgccca ccccggccgc gcgcaccaca acgcccccgc cccgccgccc       60

ggaaccagct gagcgcagct ggacccagca gccgctgtct ccagtgccgc agcagcaggt      120

agtgctcata gctctctttg tccagtgctt cggccttggt cccagcgcct tcccacggag      180

cagcactctt caccctgcac agccttgtta gcccaacagc atggtggtgg aacaccccga      240

gttcctcaag gcagggaagg agcctggcct gcagatctgg cgtgtggaga agttcgatct      300

ggtgcccgtg cccaccaacc tttatggaga cttcttcacg ggcgacgcct acgtcatcct      360

gaagacagtg cagctgagga acggaaatct gcagtatgac ctccactact ggctgggcaa      420

tgagtgcagc caggatgaga gcggggcggc cgccatcttt accgtgcagc tggatgacta      480

cctgaacggc cgggccgtgc agcaccgtga ggtccagggc ttcgagtcgg ccaccttcct      540

aggctacttc aagtctggcc tgaagtacaa gaaaggaggt gtggcatcag gattcaagca      600

cgtggtaccc aacgaggtgg tggtgcagag actcttccag gtcaaagggc ggcgtgtggt      660

ccgtgccacc gaggtacctg tgtcctggga gagcttcaac aatggcgact gcttcatcct      720

ggacctgggc aacaacatcc accagtggtg tggttccaac agcaatcggt atgaaagact      780

gaaggccaca caggtgtcca agggcatccg ggacaacgag cggagtggcc gggcccgagt      840

gcacgtgtct gaggagggca ctgagcccga ggcgatgctc caggtgctgg gccccaagcc      900

ggctctgcct gcaggtaccg aggacaccgc caaggaggat gcggccaacc gcaagctggc      960

caagctctac aaggtctcca atggtgcagg gaccatgtcc gtctccctcg tggctgatga     1020

gaaccccttc gcccaggggg ccctgaagtc agaggactgc ttcatcctgg accacggcaa     1080

agatgggaaa atctttgtct ggaaaggcaa gcaggcaaac acggaggaga ggaaggctgc     1140

cctcaaaaca gcctctgact tcatcaccaa gatggactac cccaagcaga ctcaggtctc     1200

ggtccttcct gagggcggtg agaccccact gttcaagcag ttcttcaaga actggcggga     1260

cccagaccag acagatggcc tgggcttgtc ctacctttcc agccatatcg ccaacgtgga     1320

gcgggtgccc ttcgacgccg ccaccctgca cacctccact gccatggccg cccagcacgg     1380

catggatgac gatggcacag gccagaaaca gatctggaga atcgaaggtt ccaacaaggt     1440

gcccgtggac cctgccacat atggacagtt ctatggaggc gacagctaca tcattctgta     1500

caactaccgc catggtggcc gccaggggca gataatctat aactggcagg gtgcccagtc     1560

tacccaggat gaggtcgctg catctgccat cctgactgct cagctggatg aggagctggg     1620

aggtacccct gtccagagcc gtgtggtcca aggcaaggag cccgcccacc tcatgagcct     1680

gtttggtggg aagcccatga tcatctacaa gggcggcacc tcccgcgagg gcgggcagac     1740

agcccctgcc agcacccgcc tcttccaggt ccgcgccaac agcgctggag ccacccgggc     1800

tgttgaggta ttgcctaagg ctggtgcact gaactccaac gatgcctttg ttctgaaaac     1860

cccctcagcc gcctacctgt gggtgggtac aggagccagc gaggcagaga agacgggggc     1920

ccaggagctg ctcagggtgc tgcgggccca acctgtgcag gtggcagaag gcagcgagcc     1980

agatggcttc tgggaggccc tgggcgggaa ggctgcctac cgcacatccc cacggctgaa     2040

ggacaagaag atggatgccc atcctcctcg cctctttgcc tgctccaaca agattggacg     2100

ttttgtgatc gaagaggttc ctggtgagct catgcaggaa gacctggcaa cggatgacgt     2160

catgcttctg gacacctggg accaggtctt tgtctgggtt ggaaaggatt ctcaagaaga     2220

agaaaagaca gaagccttga cttctgctaa gcggtacatc gagacggacc cagccaatcg     2280

ggatcggcgg acgcccatca ccgtggtgaa gcaaggcttt gagcctccct cctttgtggg     2340

ctggttcctt ggctgggatg atgattactg gtctgtggac cccttggaca gggccatggc     2400

tgagctggct gcctgaggag gggcagggcc cacccatgtc accggtcagt gccttttgga     2460

actgtccttc cctcaaagag gccttagagc gagcagagca gctctgctat gagtgtgtgt     2520

gtgtgtgtgt gttgtttctt tttttttttt ttacagtatc caaaaatagc cctgcaaaaa     2580

ttcagagtcc ttgcaaaatt gtctaaaatg tcagtgtttg ggaaattaaa tccaataaaa     2640

acattttgaa gtgtgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                     2685


<210>  732
<211>  2319
<212>  DNA
<213>  homo sapiens

<400>  732
ttccccactc ccccgccctc cccagggccc tgggaagggg ctcagcgtgg gaaaggatgg       60

ttgagtttta accagaggca aagcgtgagc gggatcagtg tgtgcggaac gcaagcagcc      120

gagagcggag aggcgccgct gtagttaact cctccctgcc cgccgcgccg accctcccca      180

ggaaccccca gggagccagc atgaagcgag ctcaccccga gtacagctcc tcggacagcg      240

agctggacga gaccatcgag gtggagaagg agagtgcgga cgagaatgga aacttgagtt      300

cggctctagg ttccatgtcc ccaactacat cttcccagat tttggccaga aaaagacgga      360

gaggaataat tgagaagcgc cgacgagacc ggatcaataa cagtttgtct gagctgagaa      420

ggctggtacc cagtgctttt gagaagcagg gatctgctaa gctagaaaaa gccgagatcc      480

tgcagatgac cgtggatcac ctgaaaatgc tgcatacggc aggagggaaa ggttactttg      540

acgcgcacgc ccttgctatg gactatcgga gtttgggatt tcgggaatgc ctggcagaag      600

ttgcgcgtta tctgagcatc attgaaggac tagatgcctc tgacccgctt cgagttcgac      660

tggtttcgca tctcaacaac tacgcttccc agcgggaagc cgcgagcggc gcccacgcgg      720

gcctcggaca cattccctgg gggaccgtct tcggacatca cccgcacatc gcgcacccgc      780

tgttgctgcc ccagaacggc cacgggaacg cgggcaccac ggcctcaccc acggaaccgc      840

accaccaggg caggctgggc tcggcacatc cggaggcgcc tgctttgcga gcgcccccta      900

gcggcagcct cggaccggtg ctccctgtgg tcacctccgc ctccaaactg tcgccgcctc      960

tgctctcctc agtggcctcc ctgtcggcct tccccttctc tttcggctcc ttccacttac     1020

tgtctcccaa tgcactgagc ccttcagcac ccacgcaggc tgcaaacctt ggcaagccct     1080

atagaccttg ggggacggag atcggagctt tttaaagaac tgatgtagaa tgagggaggg     1140

gaaagtttaa aatcccagct gggctggact gttgccaaca tcaccttaaa gtcgtcagta     1200

aaagtaaaaa ggaaaaaggt acactttcag ataatttttt ttttaaagac taaaggtttg     1260

ttggtttact tttatctttt ttaatgtttt tttcatcatg tcatgtatta gcagttttta     1320

aaaactagtt gttaaatttt gttcaagaca ttaaattgaa atagtgagta taagccaaca     1380

ctttgtgata ggtttgtact gtgcctaatt tactttgtaa accagaatga ttccgttttt     1440

gcctcaaaat ttggggaatc ttaacattta gtatttttgg tctgtttttc tccttgtata     1500

gttatggtct gtttttagaa ttaattttcc aaaccactat gcttaatgtt aacatgattc     1560

tgtttgttaa tattttgaca gattaaggtg ttgtataaat aatattcttt tggggggagg     1620

ggaactatat tgaattttat atttctgagc aaagcgttga caaatcagat gatcagcttt     1680

atccaagaaa gaagactagt aaattgtctg cctcctatag cagaaaggtg aatgtacaaa     1740

ctgttggtgg ccctgaatcc atctgaccag ctgctggtat ctgccaggac tggcagttct     1800

gatttagtta ggagagagcc gctgataggt taggtctcat ttggagtgtt ggtggaaagg     1860

aaactgaagg taattgaata gaatacgcct gcatttacca gccccagcaa cacaaagaat     1920

ttttaatcac acggatctca aattcacaaa tgttaacatg gataagtgat catggtgtgc     1980

gagtggtcaa ttgagtagta cagtggaaac tgttaaatgc ataacctaat tttcctggga     2040

ctgccatatt ttcttttaac tggaaatttt tatgtgagtt ttccttttgg tgcatggaac     2100

tgtggttgcc aaggtattta aaagggcttt cctgcctcct tctctttgat ttatttaatt     2160

tgatttgggc tataaaatat catttttcag gtttattctt ttagcaggtg tagttaaacg     2220

acctccactg aactgggttt gacctctgtt gtactgatgt gttgtgacta aataaaaaag     2280

aaagaacaaa gtaaaaaaaa aaaaaaaaaa aaaaaaaaa                            2319


<210>  733
<211>  6801
<212>  DNA
<213>  homo sapiens

<400>  733
gcaagtgaac cggagcaaac gacttccgat ccagtctgcg ctgttgcggc tcccgtttgg       60

gatttgattt gcagcatctt tgagcctcta cgacaaaaaa ccgcgaagca cgcccagccc      120

tcccccggca ccccgaaaag cacccactcc ctcccgggga cacagctggg cgcgtccaca      180

cccccgcagc cccacaccat gttgtgcgga aggacttcca ctccccgcct gtgtcgttga      240

tgtcagaccc caggccagcc tccgggcgct gcagttctcc cggctaatgc tgaggctgcg      300

gctccggctc tagcacaggc accagccgcc gccgcacccg gccccagcgc ccaccgtctg      360

catgtgcccg ccgtagccgt ctgcccagcc cgcagcccgc gctccacgga gcgctggaga      420

ccaccgtggg gggccccttc tgccctcgag agaagcggtc ttggaggtat tgatttaggt      480

ggttggattt tttccgtgga tctatcaatt cacaattcga atttggaaga aagaaggaaa      540

acatgacgtc tccagccaaa ttcaaaaagg ataaggagat catagcagag tacgatactc      600

aggtcaaaga gatccgtgct cagctcacag agcagatgaa atgcctggac cagcagtgtg      660

agcttcgggt gcaactgttg caggacctcc aggacttctt ccgaaagaag gcagagattg      720

agatggacta ctcccgcaac ctggagaagc tggcagaacg cttcctggcc aagacacgca      780

gcaccaagga ccagcaattc aagaaggatc agaatgttct ctctccagtc aactgctgga      840

atctcctctt aaaccaggtg aagcgggaaa gcagggacca taccaccctg agtgacatct      900

acctgaataa tatcattcct cgatttgtac aagtcagcga ggactcagga agactcttta      960

aaaagagtaa agaagtcggc cagcagctcc aagatgattt gatgaaggtc ctgaacgagc     1020

tctactcggt gatgaagaca tatcacatgt acaatgccga cagcatcagt gctcagagca     1080

aactaaagga ggcggagaag caggaggaga agcaaattgg taaatcggta aagcaggagg     1140

accggcagac cccacgctcc cctgactcca cggccaacgt tcgcattgag gagaaacatg     1200

tccggaggag ctcagtgaag aagattgaga agatgaagga gaagcgtcaa gccaagtaca     1260

cggagaataa gctgaaggcc atcaaagccc ggaatgagta cttgctggct ttggaggcaa     1320

ccaatgcatc tgtcttcaag tactacatcc atgacctatc tgaccttatt gatcagtgtt     1380

gtgacttagg ctaccatgca agtctgaacc gggctctacg caccttcctc tctgctgagt     1440

taaacctgga acagtcgaag catgagggtc tggatgccat cgagaatgca gtagaaaacc     1500

tggatgccac cagtgacaag cagcgcctca tggagatgta caacaacgtc ttctgccccc     1560

ctatgaagtt tgagtttcag ccccacatgg gggatatggc ttcccagctc tgtgcccagc     1620

agcctgtcca gagtgagctg gtacagagat gccaacaact gcagtctcgc ttatccactc     1680

taaagattga aaacgaagag gtaaagaaga caatggaggc caccctgcaa accatccagg     1740

acattgtgac tgtcgaggac tttgatgtgt ctgactgctt ccagtacagc aactccatgg     1800

agtccgtcaa gtccacggtc tctgaaacct tcatgagcaa gcccagcatt gctaagagga     1860

gagccaacca gcaagagaca gagcagtttt atttcacaaa aatgaaagag tacctggagg     1920

gcaggaacct catcaccaag ttacaagcca agcatgacct tctgcagaaa accctgggag     1980

aaagtcagcg gacagattgc agtctagcca ggcgcagctc aactgtgagg aaacaggact     2040

ccagccaggc aattcctctg gtggtggaaa gctgtatccg gtttatcagc agacacggac     2100

tacagcatga aggaattttc cgggtgtcag gatcccaggt ggaagtgaat gacatcaaaa     2160

atgcctttga gagaggagag gaccccctgg ctggggacca gaacgaccat gacatggatt     2220

ccatagctgg tgtcctgaag ctttacttcc gggggctgga acaccctctc ttccccaagg     2280

acatctttca tgacctgatg gcctgcgtca caatggacaa cctgcaggag agagctctgc     2340

acatccggaa agtcctccta gtcctgccca aaaccactct gattatcatg agatacctct     2400

ttgccttcct caatcattta tcacagttca gtgaagagaa catgatggac ccctacaacc     2460

tcgccatctg cttcgggccc tcgctaatgt cagtgccaga gggccacgac caggtgtcct     2520

gccaagccca cgtgaatgag ctgatcaaaa ccatcatcat ccagcatgag aacatcttcc     2580

caagccccag ggagctggag ggccctgtct acagcagagg aggaagcatg gaggattact     2640

gtgatagccc tcatggagag actacctcgg ttgaagactc aacccaggat gtgaccgcag     2700

agcaccacac gagcgatgac gaatgtgagc ccatcgaggc cattgccaag tttgactacg     2760

tgggccggac agcccgagag ctatccttta agaagggagc atccctgctg ctttaccagc     2820

gggcttccga cgactggtgg gaaggccggc acaatggcat cgacggactc atcccccatc     2880

agtacatcgt ggtccaagac accgaggacg gtgtcgtgga gaggtccagc cccaagtctg     2940

agattgaggt catttctgag ccacctgaag aaaaggtgac agccagagcg ggggccagct     3000

gtcccagtgg gggtcatgta gccgatattt atcttgcaaa catcaacaag caaaggaagc     3060

gtccagaatc tgggagcatc cggaaaactt ttcggagtga cagccatggg ctgagcagtt     3120

ccctgactga ctcctcctcc ccaggggtgg gggctagctg ccgcccatcc tcccagccca     3180

tcatgagcca gagcctcccc aaagaagggc cagataagtg ttccatcagt gggcacggga     3240

gcctcaactc catcagccgc cactcatccc tgaagaatcg gctggatagt ccacagatcc     3300

ggaagactgc cacagcggga aggtcaaaaa gcttcaataa ccatcggccc atggaccctg     3360

aggtcattgc tcaggatatt gaggcaacaa tgaactcggc cctgaatgag ctacgggaac     3420

tagaacggca gagcagtgtc aaacacaccc ctgacgtggt tctggacacc ttggagcccc     3480

tcaaaacctc cccagtggtg gcccccacgt cagagccctc cagccctctg cacacccagc     3540

tcctcaagga ccccgagccc gccttccagc gcagcgccag tactgctggg gacatcgcct     3600

gcgccttccg gcctgtcaag tctgtcaaga tggctgcccc ggtcaaacca ccagccacac     3660

ggcccaagcc cactgtcttc cccaaaacaa atgccactag ccctggtgtc aactcatcaa     3720

cttccccaca gtctactgac aagtcttgta ctgtctgagg gataataatt taattgttct     3780

agacaagggg actataggga ctgactgtta ttaaaatctt cctatttaac tagcttgggg     3840

acttcagttg aaaattaggt tctaagttgt tcttgcagga attagcctcc ccgtctccca     3900

aaaccttgag aatgaagccc ttggtatcgc ctctcccttc ccactgccct ctgcttcccc     3960

cagtcgtcgt aattcagcca gctgcagtcc gtaccgttct taggttagcc agagacaggt     4020

tttcattatc aggtcactgt gaaatctggt aaggcagtcc tgaggacatg ggctcaagtc     4080

tcagtcccct cagaccacgg tgatgccttg accagatggt tggctactgc catccagctt     4140

tcagtggcat cttgttttgg gaactgatta tagagaatca tatatagtcc agtcttcatt     4200

ttacatacac acacatattt tacacacaca cacattttac acacacacac acacacacac     4260

acacacatat gtttttctag tctctggcat gtgtagcctc tcctggtcat agaccagtct     4320

ctttgtaagt tattgtggca gttcacacag tagccaccag gggtctctgt ttccatcaca     4380

aactttgttc tgtctgggcc agagaaccta gcctttgaaa tctctccatc atatgaaaca     4440

taacgggatg ggacaatccc gtaacctgtt tggggttggg ggctttctct ctgtgttctt     4500

tccattgatg tgaattggtc attggtgttt gctcttgcct ctcctccatc ccctagaagt     4560

acacccccgt cttattaagg agcttttaaa gtttttctga atgtatagac atttctcggg     4620

ttcctacctt tgtctctgat ggaccatttt ccatttaaga cattttcctg tataagacag     4680

ttttatagct ggttcctttt agggtaaaga gtcttaagag agttttattg tgtctatggc     4740

aggtttggga aaggtaagaa atgggtcctt tttcctccta atgtttttgg cacttaaaac     4800

ataaaattca ttatcctatt aaaaaattaa attcagcttt gctaatccag aaattgttcc     4860

caaatgaaaa cttgttttaa gtccacccct tagtttcctt attttacaag gtctctcttc     4920

agggaccaac aggggcttag agagccttag ttagattaaa gggagaccct acctcttaaa     4980

accagttttc atttatgcaa acaaggacaa ttaagggaac cctgacccca caggctctca     5040

agtcttccca aggccagaat cgaaagaaaa ttaaaatttg aatgctgaat attctggctc     5100

tactctggcc ttttttctgg ttcccttcca aaatgcacaa atcataccct tgtctgctcc     5160

aattcagtct ccaaacctgg tgcctgtgct cctggccccc ctagcatcat gctatcccag     5220

gagtatcagg accagacaca tccacagcca ggctcatggg tctcagacag caacttgagt     5280

taaagctgaa actcatcctt cttctctgtg ttttctggtt taaaagctgc acttatattt     5340

tagccttatt attttctgta gttccggaga gatggtgggt tgccattctg gtaggaaaat     5400

ctgagttttc ttatctttga cctagaagag attctttttg gaccaacctg cgaaattggt     5460

agttaggtct atggaaagtg gtaggatttt ttttttttta atcctgtgca aaggaaaaga     5520

ggtgctttgt gggaaatcac taatgagaag gctaacctgc agcaccagag aaacctttcc     5580

aagtgctagg caggagaact gaagaactct ttcagtgaag tgagtcagcc tagaagaggc     5640

aacccacagt cttgattttt gttgctgttt cctgacctgt tcttgcctgt cacctgggcc     5700

tacacaggtc ccaagccaac ggggctttca tacccaagga tctgtttcct tgctgaaaat     5760

gaaaccctat ctttcacttt acattccttt caatccaact gatcaaaact ggtacccaca     5820

cttgcccttt ctccctctct ccagcacact cccctctaag aaagtaaaag caaagctttc     5880

ttaatggcaa cactttgggc ctgttctgtt gctcctgcct tatttctctt tcaaccctgt     5940

acatgactcg tgttcaccat ccccttgatc agtgtccatc cgcgctaatt tgcatcatga     6000

actgaacagt gtgtgagtgg tcacctacta aacccagctc tgggggcaga gctgtcttcc     6060

ccatctctgg tgctcctaac acctgtgaga tggtcctgtc gagaggacta ggaaccgata     6120

ggaggagagt ccttctcggc agagctcact gcaaacaact ggaattgagg ttgcacactg     6180

tgatttttac accgaaaagc caaaaggagc tggccatcca gggcctaggg agaccagcct     6240

tcctcagcta tgcttgccga aaccagcatg atgcttcaaa gagccctgct ccacccctca     6300

tggcatggat ccttttcctg gtgtggactc tgaagggtca gtcttcgggg aagagaggtg     6360

gggtggggct actagcatcc caatttagaa aatagaggag tttgtagcca gcagcctgta     6420

aactggaaac actggtctca gccaacctcc tcagggcgcc ctggcttctc cccaaggaga     6480

tgaggagcgg tgatgccagc accgggatgc gcagagcact ggaagggctg gtgcagatct     6540

acttcccatg cagaagagaa gtcacatctt ccagggaatc gcaatgttgt ggcgtctgac     6600

ttgtatgtca catttgtgta aaatggtata ttctttaaaa tagtgttgat aactggaata     6660

ttgtatgtat gcttggagat gctttgtgtg aacctaagac tgtcactcaa cagatgttgg     6720

attggggaaa atccaaagca caacttcaaa ataaaataca tttttaggtt tcgatgctgc     6780

aaaaaaaaaa aaaaaaaaaa a                                               6801


<210>  734
<211>  6332
<212>  DNA
<213>  homo sapiens

<400>  734
agtgacgccc ccgaacccag ctgcagaagc tgccgccacc tccaatgcac aaggtgtctc       60

atctgaaaag aaacctgagc cccagggagg cggcgcggag cgaccctggc agagctggcg      120

caaacagggc gagaggtcgc tgggcagcgt tcgaggacca gagggagctc ggccacagaa      180

gaccccagtg atctgatccc gggatcccgg ctccaagctc tcctcgcatt ttacagattt      240

cacccccgcg actatctccc caaaacggag cctttatatc aagagaaggt gcgggagctg      300

gggcaaccag gactttctcg ggcacccaag atgcgctcca ttaggaagag gtggacgatc      360

tgcacaataa gtctgctcct gatcttttat aagacaaaag aaatagcaag aactgaggag      420

caccaggaga cgcaactcat cggagatggt gaattgtctt tgagtcggtc acttgtcaat      480

agctctgata aaatcattcg aaaggctggc tcttcaatct tccagcacaa tgtagaaggt      540

tggaaaatca attcctcttt ggtcctagag ataaggaaga acatacttcg tttcttagat      600

gcagaacgag atgtgtcagt ggtcaagagc agttttaagc ctggtgatgt catacactat      660

gtgcttgaca ggcgccggac actaaacatt tctcatgatc tacatagcct cctacctgaa      720

gtttcaccaa tgaagaatcg caggtttaag acctgtgcag ttgttggaaa ttctggcatt      780

ctgttagaca gtgaatgtgg aaaggagatt gacagtcaca attttgtaat aaggtgtaat      840

ctagctcctg tggtggagtt tgctgcagat gtgggaacta aatcagattt tattaccatg      900

aatccatcag ttgtacaaag agcatttgga ggctttcgaa atgagagtga cagagaaaaa      960

tttgtgcata gactttccat gctgaatgac agtgtccttt ggattcctgc tttcatggtc     1020

aaaggaggag agaagcacgt ggagtgggtt aatgcattaa tccttaagaa taaactgaaa     1080

gtgcgaactg cctatccgtc attgagactt attcatgctg tcagaggtta ctggctgacc     1140

aacaaagttc ctatcaaaag acccagcaca ggtcttctca tgtatacact tgccacaaga     1200

ttctgtgatg aaattcacct gtatggattc tggcccttcc ctaaggattt aaatggaaaa     1260

gcggtcaaat atcattatta tgatgactta aaatataggt acttttccaa tgcaagccct     1320

cacagaatgc cattagaatt caaaacatta aatgtgctac ataatagagg agctctaaaa     1380

ctgacaacag gaaagtgtgt aaagcaataa agcacatttt gaaacaaaca atatgcactt     1440

cttttctgaa gatgcttccg aagatttgaa aataggatcc aaaacacggc tgggtttcag     1500

catccaccaa tgaactgaaa ggtgaataaa ggacgttcat gagaaatcga ctaccagctg     1560

atgaaatacc tgcaaagtgc tctaaaaatt aaatattttg actttaaggg tcctagtaag     1620

tgccacttcc actaagaata cagtttgaat gtataatcag tagtgtttac aagatccaac     1680

agtgcactca tcattagtta acaaagcaaa tatgttcatc actgtcaggc tgcccacagc     1740

aacaccaagc atattagaag aggaacccca ggaacgcaac tcagaccttg ggaaattaaa     1800

ccatccttgt cagcagaagc caagatggaa gcagtttgag caatgaaatc cgtaagatta     1860

aacaactcaa gtaaatgctt cagtcaggac tctgagtctg atcatgaatt ttatgtttta     1920

atttatgttt tttttttgtc ttctggaatc tcttttggtt tggatattgg gatgcttaga     1980

aatcctttct gagatgcata tgagtgagga aataaacttt aagtaattat ttttaaagtt     2040

cttatacttt ttaaaagcta tcacacaaag actttttttt ttttttttgt ctcgctctgt     2100

tgcccaggct ggagtacagt ggcgcgatct cagctcactg caagctccgc ctcccaagtt     2160

cactccattc tcctgcctca gcctccggag tagctgggac tgcaggcgcc tgccaccacg     2220

cctggctaat tttttgtatt tttagtggag acggattttc accgtgttag ccaggatggt     2280

ctcaatctcc tgacctcgtg atccacccgc cttggcctcc caaagtgctg ggattacagg     2340

cgtgagccac cgtgcctggc cgacattttt aaaaaagttt tattttgcac ggctctaaac     2400

ctccatgtta ttttccagtg gtgtagaagg taccagctaa agtgaaccac tatgtaatat     2460

taggccattc taaaggaaag atgttccatg tcatcagaga tggtaaaata ggccgggaaa     2520

aaaaaatctt tggtaccaaa gattacactt gtgtttctac acagcaaacc atttttcttt     2580

catgaaaata atatattatt aacatgaata tattattttg ctattaatgt gaaagttgtc     2640

tctaaatatt ttttaatttt caaactcata ctttattttc atttgaaatg tttttcacac     2700

cttttgcatt acataataat tttgtggaag cattttgccc tttagaataa atattagatt     2760

gatatagctg aaatgtgact tccagttctt tgatattccc cttgttattc aaatagaaat     2820

atggaaatgc tttatatatt actgttaaat ttcttagtgc agaaataaca ttattaatag     2880

agtattgttt tcaaaacaga gatgattaat ttcaagaggt ttaacagtga aattgtgtca     2940

atattttgca tttaaaatga atttaattga ccgatatttt ctgtagttaa atttagtcac     3000

aatatcacat atgttcttca agaaacacat gaaattatta ataaagtaat taaaaaattt     3060

ttaatgtata acagaattga ccaataggcc agttttctgg taacttatga tagtagattg     3120

tttctttaga aactgggcag aagctctgca ttctcacttg tactttgatt tcttatttct     3180

tgggcaggca atttgaggaa agaagaaatg gcatggggaa tatatatgtt ttgtttctta     3240

gggaaaacag tctgagaaat gaataaaaag catgaagtac gtgtgtgtgt gtgtgtgtta     3300

ccatggaaaa ggatattcac agtagtacag ttctcaatat ttttaattag atgtcatatt     3360

tttttaatat agtaaaacct tgggatatag aatattacat cttttgagaa tgtatgtgtc     3420

tctaagtaag taaaatctaa tgcgtatagg agactgatag ctaaaaatga atggaacatt     3480

aatgtacttt tataattaaa cctcttatct atcagaaatt gtaagagaat agatacatgt     3540

tttgaatgta aagttgaaaa gtctggttta cttaataaat tgaaagtgat ttataaaatc     3600

taaatttgga ctacttgcaa atgataagct attctagtag cctttagttt aaatccaaca     3660

gaaatctaga agtcacaagc aaatatctta aaggtaaaat ccatctgggc actcatttaa     3720

agtatatctt aaaaaagcag cagcaaggta ccttgccatt tttagcatat tttcttcctt     3780

tttctttttt cttttttttt tttttttgag atggagtctc actctgtcac acaggctgga     3840

atgcagtgat gccatctcag ctcactgcaa cctccacctc ctgggttcaa gtgattctcg     3900

tgcctcagcc tcccaagtag ctggggttac aggcgcccac caccacactc ggctaatttt     3960

gtgtttttag tagagacaaa gtttcaccat gttggccagg ctggtcttga acttcctgac     4020

ctcaggttat ccacccacct cagcctccca aagtgctggg attacaggtg tgagccaccg     4080

cagccggacc atttttagta tattttcagt aaatacattt aaacaatgtt aaggccacag     4140

cacacatatc tcagccattc attgttctgt gcattgatgt ttatctcata gatgcattga     4200

gtagtgcctt tttagctttt tcacattact ttgtcaccat atcctttgtg ttctctaaat     4260

acattgccca cttccaaaaa tgttcagcat gaaaaaaagg gcttcagtgt cgattgagat     4320

tgcttttgtt catctcaggg atttcaatag tcaagaatga attcagttaa aggtatttag     4380

ggttcaaaga agacaaactg tacaagccca tttcattcct tgttgtatac ctttccatct     4440

gccctcccat tttaactatc tactgtggcc tttttatgga aacagagcaa gatcaatgaa     4500

ggctaatggc aagaataaga aaaagagttg agatttaacc aatagcggag cataaaggat     4560

catgacaaaa tcaaattata aaagcatact tgaaataggt ggagcttttt cttttgaaaa     4620

tatatattca caattttaat attttaattt attttttact atttaaccct gtacttggca     4680

atgctcaggc agctgattgt gaaatattct tgtcctttac agaacatggt tgttattgtg     4740

ctgttgacat gaatagacca tggaaacatt ttcatcatta ttattcagcc tgtgctgtag     4800

ttaatgttaa gttgctgaaa taaaaagtga gcaagtaata gattttcttg gcaaatctaa     4860

tgattcagcc cacaggactg ttgaaactac tgcggaagtt tttctatctg aaagaaggtg     4920

ctgggcattc aaatgtgttc atgtattgta tatcatatga attgtatatc aattactaat     4980

gggaatttct acatatatgc ttacaaaagc aatttattta agtaatgcta ggggtagtgt     5040

acataccaat tagttattca gctactatac agaaaaagga tgaacaaatt aatttatttc     5100

taattgagcc agttagacat aatgcatata acgtgatatt tggttcatga aagagttgtt     5160

ttcatgtggt tattgtaggg agtatatata attgtggaag gggtatggga agagttgtgt     5220

atagttagtt gttatctcta caagtttgaa agttttccca tcaaacatta tcaatatacc     5280

aatgttttaa aaattgagtg agggttatta tttgtatttg atgaaagaaa atccaaataa     5340

agcccaccta gaaatagata ttttattata tatgtgctat agatatacct atatagtaca     5400

aatagacatg tgtgatgcat atatacaatg ttatatatgt gtatatgtct gtatacacac     5460

tgagtctgta atatgtatac actaaatttg tgttatgcta acatcttcag ggtctgcact     5520

gtgaactccc ctggagataa gtaagtccac tttagaataa agaagttctt ttgagacttc     5580

agttactaac gtgctttaag aggtatctac tttataactg aattctatgt cgttcatacg     5640

tagagttaca gtaagggtct agtatgtcca aatcttaata ataaagaaga aaagtaaagg     5700

cttcaagcta gcaatgtatt cgaattacag ttttcagatt gtggctccag gccttgtgtt     5760

tctcatttaa gtagcacctt ttaataaaaa ccgtttcttt gtgtaggcaa aagcacaagt     5820

gtttcaaatg taaatagcag gaaaaaaaaa gagtttacag agatagcatt gctgcacaga     5880

ataattgcta ctgagtattt cttatagaat ttgtggaact gaaagatgag gtttattctg     5940

tcaagttcaa gttcattctg ttcaacactg ttttcttatt gtttgtgtat agcaaccggg     6000

tattattgtt ttatcatttg taaaattgta aaataaatta atcccttttt ttcactgttt     6060

ctcttatctc atatatccaa gcccttggtt atactttgta tgtcaatgtt aggtgatcat     6120

ttttaacaag ctttggcttg tgctttgctt ttccactccc cttagcccta gtggttggca     6180

attaggcaaa ccatttattt ttaagtgtat acatgggaat atgaacaatg tcaaaaaccc     6240

catgaatatt aggaaatcct taacgatatt ttgtgtagca cattctgttt gcggttgagg     6300

gaataaagta tttcacaagt gaaaaaaaaa aa                                   6332


<210>  735
<211>  5308
<212>  DNA
<213>  homo sapiens

<400>  735
gagacaccac tgaatacaga gcagcgagca ctgaaggctt ccctctttcc ttaaacctgt       60

cgggttgtgg gctctctctt ttcccctctt gctcctttct tttctttttt tctgtttttt      120

taaaccttcc aaggcaagtt catggatact aagctgatgt gtttgttgtt ctttttctcc      180

ctgcctccgc tcctagtgag taaccacact ggccgcatca aggtggtctt tactccgagc      240

atctgtaaag tgacctgcac caagggcagc tgtcagaaca gctgtgagaa ggggaacacc      300

accactctca ttagtgagaa tggtcatgct gccgacaccc tgacggccac gaacttccga      360

gtggtaattt gccatcttcc atgtatgaat ggtggccagt gcagttcaag ggacaaatgt      420

cagtgccctc caaatttcac aggaaaactt tgtcagatcc cagtccatgg tgccagcgtg      480

cctaaacttt atcagcattc ccagcagcca ggcaaggcgt tggggacgca tgtcatccat      540

tcaacacata ccttgcctct gaccgtgact agccagcaag gagtcaaagt gaaatttcct      600

cctaacatag tcaatatcca tgtgaaacat cctcctgaag cttccgtcca gatacatcag      660

gtttcaagaa ttgatggccc aacaggccag aagacaaaag aagctcaacc aggccaatcc      720

caagtctcgt accaagggct tcctgtccag aagacccaga ccatacattc cacatactcc      780

caccagcagg tcattcctca cgtctacccc gtggctgcta agacacagct tggccggtgc      840

ttccaggaaa ccattgggtc acagtgtggc aaagcgctcc ctggcctttc aaagcaagag      900

gactgctgtg gaactgtggg tacctcctgg ggctttaaca aatgccagaa atgccccaag      960

aaaccatctt atcatggata caaccaaatg atggaatgcc taccgggtta taagcgggtt     1020

aacaacacct tttgccaaga tattaatgaa tgtcagctac aaggtgtatg ccctaatggt     1080

gagtgtttga ataccatggg cagctatcga tgtacctgca aaataggatt tgggccggat     1140

cctacctttt caagttgtgt tcctgatccc cctgtgatct cggaagagaa agggccctgt     1200

taccgacttg tcagttctgg aagacagtgt atgcaccctc tgtctgttca cctcaccaag     1260

cagctctgct gttgtagtgt gggcaaggcc tggggcccac actgtgagaa atgtcccctt     1320

ccaggcacag ctgcttttaa ggaaatctgt cctggtggaa tgggttatac ggtttctggc     1380

gttcatagac gcaggccaat ccatcaccat gtaggtaaag gacctgtatt tgtcaagcca     1440

aagaacactc aacctgttgc taaaagtact catcctccac ctctcccagc caaggaagag     1500

ccagtggagg ccctgacctt ctcccgggaa cacgggccag gagtggcgga gccagaagtg     1560

gcaactgcac cccctgaaaa ggaaatacct tcattggatc aagagaaaac caaacttgag     1620

cctggtcaac cccagctgtc tccaggcatt tccactattc atctgcatcc acagtttcca     1680

gtagtgattg aaaaaacatc acctcctgtg cctgttgaag tagctcctga agcttctacg     1740

tctagtgcca gccaagtgat tgctcctact caagtgacag aaatcaatga atgtactgtg     1800

aaccctgata tctgtggagc aggacactgc attaacctac cagtgagata tacctgtata     1860

tgctacgagg gctacaggtt cagtgaacaa cagaggaaat gtgtggatat tgatgagtgt     1920

actcaggtcc aacacctctg ctcccagggc cgctgtgaaa acaccgaggg aagtttcttg     1980

tgcatttgcc cagcaggatt tatggccagt gaggagggta ctaactgcat agatgttgac     2040

gaatgcctga ggccggacgt ctgtggggag gggcactgtg tcaatactgt gggggccttc     2100

cggtgtgaat actgtgacag cgggtaccgc atgactcaga gaggccgttg tgaggatatt     2160

gatgaatgtt tgaatccaag cacttgtcca gatgagcagt gtgtgaattc tcctggatct     2220

taccagtgcg ttccctgcac agaaggattc cgaggctgga atggacagtg ccttgatgtg     2280

gacgagtgcc tggaaccaaa cgtctgcgca aatggtgatt gttccaacct tgaaggctcc     2340

tacatgtgtt catgccacaa aggctatacc cggactccgg accacaagca ctgtagagat     2400

attgatgaat gtcagcaagg gaatctatgt gtaaacgggc agtgcaaaaa taccgagggc     2460

tccttcaggt gcacctgtgg acaggggtac cagctgtcgg cagctaaaga ccagtgtgaa     2520

gacattgatg aatgccagca ccgtcatctc tgtgctcatg ggcagtgcag gaacactgag     2580

ggctcttttc aatgtgtgtg tgaccagggt tacagagcat ctgggcttgg agaccactgt     2640

gaagatatca atgaatgctt ggaggacaag agtgtttgcc agagaggaga ctgcattaat     2700

actgcagggt cctatgattg tacttgtccg gatggatttc agctagatga caataaaaca     2760

tgtcaagata ttaatgaatg tgaacatcca gggctctgtg gtccgcaagg ggagtgccta     2820

aacacagagg gttctttcca ttgtgtctgc cagcagggtt tctcaatctc tgcagatggc     2880

cgtacgtgtg aagatattga tgaatgtgta aacaacactg tttgtgacag tcacgggttt     2940

tgtgacaata cagctggctc cttccgctgc ctctgttatc agggctttca agccccacag     3000

gatgggcaag ggtgtgtgga tgtgaatgaa tgtgaactgc tcagtggggt gtgtggtgaa     3060

gccttctgtg aaaacgtgga agggtccttc ctgtgcgtgt gtgctgatga aaaccaagag     3120

tacagcccca tgactgggca gtgccgctcc cggacctcca cagatttaga tgtagatgta     3180

gatcaaccca aagaagaaaa gaaagaatgc tactataatc tcaatgacgc cagtctctgt     3240

gataatgtgt tggcccccaa tgtcacgaaa caagaatgct gctgtacatc aggcgcggga     3300

tggggagata actgcgaaat cttcccctgc ccggtcttgg gaactgctga gttcactgaa     3360

atgtgtccca aagggaaagg ttttgtgcct gctggagaat catcttctga agctggtggt     3420

gagaactata aagatgcaga tgaatgccta ctttttggac aagaaatctg caaaaatggt     3480

ttctgtttga acactcggcc tgggtatgaa tgctactgta agcaagggac gtactatgat     3540

cctgtgaaac tgcagtgctt tgatatggat gaatgtcaag accccagtag ttgtattgat     3600

ggccagtgtg ttaatacaga gggctcttac aactgcttct gtactcaccc catggtcctg     3660

gatgcgtcag aaaaaagatg tatacgaccg gctgagtcaa acgaacaaat agaagaaact     3720

gatgtctacc aagatttgtg ctgggaacat ctgagtgatg aatacgtgtg tagccggcct     3780

cttgtgggca agcagacaac gtacactgag tgctgctgtc tgtatggaga ggcctggggc     3840

atgcagtgtg ccctctgccc cctgaaggat tcagatgact atgctcagct gtgtaacatc     3900

cccgtgacgg gacgccggca gccatatgga cgggacgcct tggttgactt cagtgaacag     3960

tatactccag aagccgatcc ctacttcatc caagaccgtt ttctaaatag ctttgaggag     4020

ttacaggctg aggaatgcgg catcctcaat ggatgtgaaa atggtcgctg tgtgagggtc     4080

caggaaggtt acacctgcga ttgctttgat gggtatcact tggatacggc caagatgacc     4140

tgtgtcgatg taaatgaatg cgatgagttg aacaaccgga tgtctctctg caagaatgcc     4200

aagtgcatta acaccgatgg ttcctacaag tgtttgtgtc tgccaggcta cgtgccttct     4260

gacaagccaa actactgcac tccgttgaat accgccttga atttagagaa agacagtgac     4320

ctggagtgaa acagaatcta cataacctaa gcccatatac tctgcactgt gtaaaggaaa     4380

agggagaaat gtattatact tgagacattg cacctacccc ggaaggctgg aaatacagaa     4440

acagcatgga attgcaagtc ctctgaagac aatgagagga tttaggatga gcccgatagg     4500

tgtggcagac caaatggaca tttctctaaa aaaccagtat atatagtctg ttcatatgta     4560

aaattcaatg gaagagaggt ggaacagtgc tgttatttta aacagaaggt tgtattatta     4620

tgttgttttg tttttttact attgcttgat taaatttggc atttaaatag tggtggaaat     4680

attttatata attttcattt tttggttgtg cagttccttg gctactgttt ttcttttact     4740

tcagtttttt aaaaatctca aatgaaaaag tcttcgatac aatattgtta agctgtatta     4800

taagtattgt tacacagggt tatgcaattc ccggcctgga gcatttttga aattcaaatt     4860

gtctgtcctg tggagcaggc agtgattttg ttccaaaact ttgtatacac atttggagaa     4920

aagtacttta tattttcagt gttttgtctg attttaatgt ccgttcttag ccaagctgct     4980

agcaggtgtt aattggatcc ctttccttca ctgaaatgga agagtttata agcttacgtt     5040

agtattgtaa tatgtaaagt aagcccaaca aaaattttta aaaatttgat gatccccaat     5100

atatctacca ttgtatgtta aataaatcac catttttgta gaaaaaattc tacctgagag     5160

taattgtcaa tgagtacatg tgtataagtt gtatcccact ctccccactt ttatcttttc     5220

cagtggtctt ctgttaatgt agtgtctttt acaagttaat cattaaattt gttagatctt     5280

gttatgggct aaaaaaaaaa aaaaaaaa                                        5308


<210>  736
<211>  5182
<212>  DNA
<213>  homo sapiens

<400>  736
gagacaccac tgaatacaga gcagcgagca ctgaaggctt ccctctttcc ttaaacctgt       60

cgggttgtgg gctctctctt ttcccctctt gctcctttct tttctttttt tctgtttttt      120

taaaccttcc aaggcaagtt catggatact aagctgatgt gtttgttgtt ctttttctcc      180

ctgcctccgc tcctagtgag taaccacact ggccgcatca aggtggtctt tactccgagc      240

atctgtaaag tgacctgcac caagggcagc tgtcagaaca gctgtgagaa ggggaacacc      300

accactctca ttagtgagaa tggtcatgct gccgacaccc tgacggccac gaacttccga      360

gtggtaattt gccatcttcc atgtatgaat ggtggccagt gcagttcaag ggacaaatgt      420

cagtgccctc caaatttcac aggaaaactt tgtcagatcc cagtccatgg tgccagcgtg      480

cctaaacttt atcagcattc ccagcagcca ggcaaggcgt tggggacgca tgtcatccat      540

tcaacacata ccttgcctct gaccgtgact agccagcaag gagtcaaagt gaaatttcct      600

cctaacatag tcaatatcca tgtgaaacat cctcctgaag cttccgtcca gatacatcag      660

gtttcaagaa ttgatggccc aacaggccag aagacaaaag aagctcaacc aggccaatcc      720

caagtctcgt accaagggct tcctgtccag aagacccaga ccatacattc cacatactcc      780

caccagcagg tcattcctca cgtctacccc gtggctgcta agacacagct tggccggtgc      840

ttccaggaaa ccattgggtc acagtgtggc aaagcgctcc ctggcctttc aaagcaagag      900

gactgctgtg gaactgtggg tacctcctgg ggctttaaca aatgccagaa atgccccaag      960

aaaccatctt atcatggata caaccaaatg atggaatgcc taccgggtta taagcgggtt     1020

aacaacacct tttgccaaga tattaatgaa tgtcagctac aaggtgtatg ccctaatggt     1080

gagtgtttga ataccatggg cagctatcga tgtacctgca aaataggatt tgggccggat     1140

cctacctttt caagttgtgt tcctgatccc cctgtgatct cggaagagaa agggccctgt     1200

taccgacttg tcagttctgg aagacagtgt atgcaccctc tgtctgttca cctcaccaag     1260

cagctctgct gttgtagtgt gggcaaggcc tggggcccac actgtgagaa atgtcccctt     1320

ccaggcacag ctgcttttaa ggaaatctgt cctggtggaa tgggttatac ggtttctggc     1380

gttcatagac gcaggccaat ccatcaccat gtaggtaaag gacctgtatt tgtcaagcca     1440

aagaacactc aacctgttgc taaaagtact catcctccac ctctcccagc caaggaagag     1500

ccagtggagg ccctgacctt ctcccgggaa cacgggccag gagtggcgga gccagaagtg     1560

gcaactgcac cccctgaaaa ggaaatacct tcattggatc aagagaaaac caaacttgag     1620

cctggtcaac cccagctgtc tccaggcatt tccactattc atctgcatcc acagtttcca     1680

gtagtgattg aaaaaacatc acctcctgtg cctgttgaag tagctcctga agcttctacg     1740

tctagtgcca gccaagtgat tgctcctact caagtgacag aaatcaatga atgtactgtg     1800

aaccctgata tctgtggagc aggacactgc attaacctac cagtgagata tacctgtata     1860

tgctacgagg gctacaggtt cagtgaacaa cagaggaaat gtgtggatat tgatgagtgt     1920

actcaggtcc aacacctctg ctcccagggc cgctgtgaaa acaccgaggg aagtttcttg     1980

tgcatttgcc cagcaggatt tatggccagt gaggagggta ctaactgcat agatgttgac     2040

gaatgcctga ggccggacgt ctgtggggag gggcactgtg tcaatactgt gggggccttc     2100

cggtgtgaat actgtgacag cgggtaccgc atgactcaga gaggccgttg tgaggatatt     2160

gatgaatgtt tgaatccaag cacttgtcca gatgagcagt gtgtgaattc tcctggatct     2220

taccagtgcg ttccctgcac agaaggattc cgaggctgga atggacagtg ccttgatgtg     2280

gacgagtgcc tggaaccaaa cgtctgcgca aatggtgatt gttccaacct tgaaggctcc     2340

tacatgtgtt catgccacaa aggctatacc cggactccgg accacaagca ctgtagagat     2400

attgatgaat gtcagcaagg gaatctatgt gtaaacgggc agtgcaaaaa taccgagggc     2460

tccttcaggt gcacctgtgg acaggggtac cagctgtcgg cagctaaaga ccagtgtgaa     2520

gacattgatg aatgccagca ccgtcatctc tgtgctcatg ggcagtgcag gaacactgag     2580

ggctcttttc aatgtgtgtg tgaccagggt tacagagcat ctgggcttgg agaccactgt     2640

gaagatatca atgaatgctt ggaggacaag agtgtttgcc agagaggaga ctgcattaat     2700

actgcagggt cctatgattg tacttgtccg gatggatttc agctagatga caataaaaca     2760

tgtcaagata ttaatgaatg tgaacatcca gggctctgtg gtccgcaagg ggagtgccta     2820

aacacagagg gttctttcca ttgtgtctgc cagcagggtt tctcaatctc tgcagatggc     2880

cgtacgtgtg aagatgtgaa tgaatgtgaa ctgctcagtg gggtgtgtgg tgaagccttc     2940

tgtgaaaacg tggaagggtc cttcctgtgc gtgtgtgctg atgaaaacca agagtacagc     3000

cccatgactg ggcagtgccg ctcccggacc tccacagatt tagatgtaga tgtagatcaa     3060

cccaaagaag aaaagaaaga atgctactat aatctcaatg acgccagtct ctgtgataat     3120

gtgttggccc ccaatgtcac gaaacaagaa tgctgctgta catcaggcgc gggatgggga     3180

gataactgcg aaatcttccc ctgcccggtc ttgggaactg ctgagttcac tgaaatgtgt     3240

cccaaaggga aaggttttgt gcctgctgga gaatcatctt ctgaagctgg tggtgagaac     3300

tataaagatg cagatgaatg cctacttttt ggacaagaaa tctgcaaaaa tggtttctgt     3360

ttgaacactc ggcctgggta tgaatgctac tgtaagcaag ggacgtacta tgatcctgtg     3420

aaactgcagt gctttgatat ggatgaatgt caagacccca gtagttgtat tgatggccag     3480

tgtgttaata cagagggctc ttacaactgc ttctgtactc accccatggt cctggatgcg     3540

tcagaaaaaa gatgtatacg accggctgag tcaaacgaac aaatagaaga aactgatgtc     3600

taccaagatt tgtgctggga acatctgagt gatgaatacg tgtgtagccg gcctcttgtg     3660

ggcaagcaga caacgtacac tgagtgctgc tgtctgtatg gagaggcctg gggcatgcag     3720

tgtgccctct gccccctgaa ggattcagat gactatgctc agctgtgtaa catccccgtg     3780

acgggacgcc ggcagccata tggacgggac gccttggttg acttcagtga acagtatact     3840

ccagaagccg atccctactt catccaagac cgttttctaa atagctttga ggagttacag     3900

gctgaggaat gcggcatcct caatggatgt gaaaatggtc gctgtgtgag ggtccaggaa     3960

ggttacacct gcgattgctt tgatgggtat cacttggata cggccaagat gacctgtgtc     4020

gatgtaaatg aatgcgatga gttgaacaac cggatgtctc tctgcaagaa tgccaagtgc     4080

attaacaccg atggttccta caagtgtttg tgtctgccag gctacgtgcc ttctgacaag     4140

ccaaactact gcactccgtt gaataccgcc ttgaatttag agaaagacag tgacctggag     4200

tgaaacagaa tctacataac ctaagcccat atactctgca ctgtgtaaag gaaaagggag     4260

aaatgtatta tacttgagac attgcaccta ccccggaagg ctggaaatac agaaacagca     4320

tggaattgca agtcctctga agacaatgag aggatttagg atgagcccga taggtgtggc     4380

agaccaaatg gacatttctc taaaaaacca gtatatatag tctgttcata tgtaaaattc     4440

aatggaagag aggtggaaca gtgctgttat tttaaacaga aggttgtatt attatgttgt     4500

tttgtttttt tactattgct tgattaaatt tggcatttaa atagtggtgg aaatatttta     4560

tataattttc attttttggt tgtgcagttc cttggctact gtttttcttt tacttcagtt     4620

ttttaaaaat ctcaaatgaa aaagtcttcg atacaatatt gttaagctgt attataagta     4680

ttgttacaca gggttatgca attcccggcc tggagcattt ttgaaattca aattgtctgt     4740

cctgtggagc aggcagtgat tttgttccaa aactttgtat acacatttgg agaaaagtac     4800

tttatatttt cagtgttttg tctgatttta atgtccgttc ttagccaagc tgctagcagg     4860

tgttaattgg atccctttcc ttcactgaaa tggaagagtt tataagctta cgttagtatt     4920

gtaatatgta aagtaagccc aacaaaaatt tttaaaaatt tgatgatccc caatatatct     4980

accattgtat gttaaataaa tcaccatttt tgtagaaaaa attctacctg agagtaattg     5040

tcaatgagta catgtgtata agttgtatcc cactctcccc acttttatct tttccagtgg     5100

tcttctgtta atgtagtgtc ttttacaagt taatcattaa atttgttaga tcttgttatg     5160

ggctaaaaaa aaaaaaaaaa aa                                              5182


<210>  737
<211>  2566
<212>  DNA
<213>  homo sapiens

<400>  737
ggcctgcagg gagcagccgc gagccggccg ggcgcgccga gcccgagccc cagccggagc       60

ggggcggggg agggaggagc cagagcggcc gccgcctctg ccggaggagc cgcggggccg      120

ccacactcgc cccccgcccc ccccgcgctc actcgcactc acacccgggc gcaggaggcg      180

ggcggcccgg gccccaccgg ccccccatgg acgcccccag cacggggcgc tgagaccccc      240

gcgtcgctgc ccagcccggt ccggcgcgcc acgccgaggg atctctggac aggacaagac      300

tccgaagcta ctcccccagc acacagcccg ggacccacaa acccagcttg cccccagccc      360

tcccacctgc cactccctgg cccctcccac cgcccgcccc ccttggggcg cagggcatgg      420

tgtgaaaggc caagtgctga ggcgggtatc atgggtgctg tgccctaggg cctgggtggc      480

agggggtggg tggcctgtgg gtgtgccggg ggggccagtg tgcccacccc agtctcttgg      540

cgtgctggag ggcatcctgg atggaattga agtgaatgga acagaagcca agcaaggtgg      600

agtgtgggtc agacccagag gagaacagtg ccaggtcacc agatggaaag cgaaaaagaa      660

agaacggcca atgttccctg aaaaccagca tgtcagggta tatccctagt tacctggaca      720

aagacgagca gtgtgtcgtg tgtggggaca aggcaactgg ttatcactac cgctgtatca      780

cttgtgaggg ctgcaagggc ttctttcgcc gcacaatcca gaagaacctc catcccacct      840

attcctgcaa atatgacagc tgctgtgtca ttgacaagat cacccgcaat cagtgccagc      900

tgtgccgctt caagaagtgc atcgccgtgg gcatggccat ggacttggtt ctagatgact      960

cgaagcgggt ggccaagcgt aagctgattg agcagaaccg ggagcggcgg cggaaggagg     1020

agatgatccg atcactgcag cagcgaccag agcccactcc tgaagagtgg gatctgatcc     1080

acattgccac agaggcccat cgcagcacca atgcccaggg cagccattgg aaacagaggc     1140

ggaaattcct gcccgatgac attggccagt cacccattgt ctccatgccg gacggagaca     1200

aggtggacct ggaagccttc agcgagttta ccaagatcat caccccggcc atcacccgtg     1260

tggtggactt tgccaaaaaa ctgcccatgt tctccgagct gccttgcgaa gaccagatca     1320

tcctcctgaa ggggtgctgc atggagatca tgtccctgcg ggcggctgtc cgctacgacc     1380

ctgagagcga caccctgacg ctgagtgggg agatggctgt caagcgggag cagctcaaga     1440

atggcggcct gggcgtagtc tccgacgcca tctttgaact gggcaagtca ctctctgcct     1500

ttaacctgga tgacacggaa gtggctctgc tgcaggctgt gctgctaatg tcaacagacc     1560

gctcgggcct gctgtgtgtg gacaagatcg agaagagtca ggaggcgtac ctgctggcgt     1620

tcgagcacta cgtcaaccac cgcaaacaca acattccgca cttctggccc aagctgctga     1680

tgaaggagag agaagtgcag agttcgattc tgtacaaggg ggcagcggca gaaggccggc     1740

cgggcgggtc actgggcgtc cacccggaag gacagcagct tctcggaatg catgttgttc     1800

agggtccgca ggtccggcag cttgagcagc agcttggtga agcgggaagt ctccaagggc     1860

cggttcttca gcaccagagc ccgaagagcc cgcagcagcg tctcctggag ctgctccacc     1920

gaagcggaat tctccatgcc cgagcggtct gtggggaaga cgacagcagt gaggcggact     1980

ccccgagctc ctctgaggag gaaccggagg tctgcgagga cctggcaggc aatgcagcct     2040

ctccctgaag ccccccagaa ggccgatggg gaaggagaag gagtgccata ccttctccca     2100

ggcctctgcc ccaagagcag gaggtgcctg aaagctggga gcgtgggctc agcagggctg     2160

gtcacctccc atcccgtaag accaccttcc cttcctcagc aggccaaaca tggccagact     2220

cccttgcttt ttgctgtgta gttccctctg cctgggatgc ccttccccct ttctctgcct     2280

ggcaacatct tacttgtcct ttgaggcccc aactcaagtg tcacctcctt ccccagctcc     2340

cccaggcaga aatagttgtc tgtgcttcct tggttcatgc ttctactgtg acacttatct     2400

cactgtttta taattagtcg ggcatgagtc tgtttcccaa gctagactgt gtctgaatca     2460

tgtctgtatc cccagtgccc ggtgcagggc ctggcataga gtaggtactc cataaaaggt     2520

gtgttgaatt gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                    2566


<210>  738
<211>  1343
<212>  DNA
<213>  homo sapiens

<400>  738
catctgggga cgctctcagg tcttggtgcc cagcccagct tccttcaaaa tatctgctgt       60

tcatgaaatc ctgtgcaagc tcagcttgga gggtgaacac tctacactcc caagtgcatt      120

tgggtcagtc aaagcctaca ccaaatttga tgctgagcag gatgctttga acattgaaat      180

ggccatcaag accaaaggtg tggatgagat caccactgtc aacattttga ctaaccacag      240

caatgcacag agacaggata ttgccttcac ctaccagaga aggaccaaaa aggaacttgt      300

atcagcactt aagtcagcct tatctggcca cctagatagt ggctttgggc ctattaaaga      360

cacctgctca gtatgatgct tctgagctaa aatcttccat gaaggggctg ggaaccaaca      420

aggactccct cattgagatc atctgctcaa gaaccaacca agagctgcag gaaattaaca      480

gagtctacaa ggaaatgtac aagactgatc tggagaagga cattatttcg gacacatctg      540

gtgacttctg caagctgatg gttgccctgg caaagggtag aagagcagag gatggctctg      600

tcattgatta tgaactgatt gaccaagatg cccgggatct ctatgacgct ggggtgaaga      660

ggaaaggaac tgaagttccc aagtggatca gcgtcatgac cgagcggagc atgtcccact      720

tccagaaagt atttgatagg tacaagagct acagtcctta tgacatgttg gagagcatca      780

agaaagaggt taaaggagac ctggaaaatt ctttcctgaa cctggtccag tgtattcaga      840

acaagcccct gtatttcgct gaccggctgt acgactccat aatgggcatg gggactcaag      900

ataaggtcct gatcagaatc atggtctccc acaatgaagt ggacatgttg aaaattaggt      960

ctgaattcaa gagaaagtat agcaagtccc tgtactatta catccagcaa gacactaagg     1020

gtgctgtacc tgtgtggtgg agatggctga agtccgacac agcacgagcg tccagaaatg     1080

gtgctcccca tgcttccagc taacaggtct agaaaacccg cttgtgacta gcagtccctg     1140

tggctgttcc tgtgaggatg acgttagcat tgcccccaac ctcattttag ttgcctaagc     1200

attgcctggc tttcctgtct agtctctcct gtaagccaaa gaaatgaaca ttccaaggaa     1260

ttggaagtga agtctatgat gtgaaacact ttgcctcctg tgtactgtgt cataaacgga     1320

ttaataaact gaatttgtac ttt                                             1343


<210>  739
<211>  1705
<212>  DNA
<213>  homo sapiens

<400>  739
cagaggtcag acggtctagc gctgcgtggg ccatggtgca gctccgaccg cgagcgtctc       60

gcgccccggc gtcggcggag gcgatggtgg acgagggcca gctggcctcg gaggaggagg      120

aggcggagca cgggctgttg ctcgggcagc ccagcagcgg cgcggccgcc gagcccctgg      180

aggaagacga ggaaggggac gatgagtttg acgatgaggc cccggaggag ctgactttcg      240

ccagcgccca ggcggaagcg agagaagagg agcggcgagt gcgggagacc gtgcgcaggg      300

ataaaacgct cctgaaggag aagaggaagc gacgcgagga gctgttcatc gaacagaaga      360

aaagaaaact ccttccagac actattttgg agaagttaac cacagcttca cagactaaca      420

tcaagaaatc gccaggaaag gtgaaagaag ttaatttgca aaagaaaaat gaagactgtg      480

aaaaaggaaa tgactccaag aaagttaaag tacaaaaagt acagtctgtc agccagaata      540

aaagctactt ggccgtaagg ctaaaagacc aagatctgag agattcaagg caacaagcag      600

cacaagcctt catacataat tcattatatg ggccaggaac caacaggact actgtaaata      660

agttcctgtc tcttgccaac aagaggttac cagtgaaaag agctgctgtc cagtttttga      720

ataatgcttg gggaatccaa aaaaaacaaa atgccaagag gtttaaaaga cggtggatgg      780

tcagaaagat gaaaactaag aagtaaatca atgctaaatg aagaatctgt actttgtatg      840

tatagaattt atctaataaa tcattcatag atcattttaa aggatcatta taaaaatcat      900

aaacctattt gaggaagtgc tcaaccacat ttcattcttc tggagtagaa ctgtgccttg      960

caatcctaga ggaaaaagtg gtttaagaag gaattgtttt ctttttaata tatttaactg     1020

aattcaagcc atacccacat cagcaacagc acctcttcta ctctccccgg gttagagggg     1080

tggcaaaaat ggcacggact aaaaggagaa atggatattc cagcaaagtc tctaactgca     1140

gcctgtagac aatttgctat taaagattca gtgcacaaaa tatagctaac agcttttaaa     1200

tttttacttt taaccagtct ggggatttgc ttgcctggtg agtctcatat gccatattat     1260

gaatatgaaa ataatgaagt taatttcctg ttgcctttct gtgtcagcca caatatcagg     1320

tctaacccta atccagggat gccagtaaac tgaaggcaat tttaggttgt agaactcaga     1380

ttaattgtag aaaccattaa ttttaattgc tctaattttc atagtaatca taaaaagtat     1440

gcaagtacct aatatataaa ctcaattgac actgtatctg tagaagtaaa tttttaatgg     1500

ctggttaatt atatcactac attttattgc aatatagtac tcatttaagc acttaaaaat     1560

ggaaggtgta caaagattaa attaagacac ggtaaattga ctaaatattt ggtttttata     1620

taaataaagg tcataaccac accgttgaca tgtaatactg ttataataca acagttaaac     1680

ttgtgagtct aaaaaaaaaa aaaaa                                           1705


<210>  740
<211>  1705
<212>  DNA
<213>  homo sapiens

<400>  740
cagaggtcag acggtctagc gctgcgtggg ccatggtgca gctccgaccg cgagcgtctc       60

gcgccccggc gtcggcggag gcgatggtgg acgagggcca gctggcctcg gaggaggagg      120

aggcggagca cgggctgttg ctcgggcagc ccagcagcgg cgcggccgcc gagcccctgg      180

aggaagacga ggaaggggac gatgagtttg acgatgaggc cccggaggag ctgactttcg      240

ccagcgccca ggcggaagcg agagaagagg agcggcgagt gcgggagacc gtgcgcaggg      300

ataaaacgct cctgaaggag aagaggaagc gacgcgagga gctgttcatc gaacagaaga      360

aaagaaaact ccttccagac actattttgg agaagttaac cacagcttca cagactaaca      420

tcaagaaatc gccaggaaag gtgaaagaag ttaatttgca aaagaaaaat gaagactgtg      480

aaaaaggaaa tgactccaag aaagttaaag tacaaaaagt acagtctgtc agccagaata      540

aaagctactt ggccgtaagg ctaaaagacc aagatctgag agattcaagg caacaagcag      600

cacaagcctt catacataat tcattatatg ggccaggaac caacaggact actgtaaata      660

agttcctgtc tcttgccaac aagaggttac cagtgaaaag agctgctgtc cagtttttga      720

ataatgcttg gggaatccaa aaaaaacaaa atgccaagag gtttaaaaga cggtggatgg      780

tcagaaagat gaaaactaag aagtaaatca atgctaaatg aagaatctgt actttgtatg      840

tatagaattt atctaataaa tcattcatag atcattttaa aggatcatta taaaaatcat      900

aaacctattt gaggaagtgc tcaaccacat ttcattcttc tggagtagaa ctgtgccttg      960

caatcctaga ggaaaaagtg gtttaagaag gaattgtttt ctttttaata tatttaactg     1020

aattcaagcc atacccacat cagcaacagc acctcttcta ctctccccgg gttagagggg     1080

tggcaaaaat ggcacggact aaaaggagaa atggatattc cagcaaagtc tctaactgca     1140

gcctgtagac aatttgctat taaagattca gtgcacaaaa tatagctaac agcttttaaa     1200

tttttacttt taaccagtct ggggatttgc ttgcctggtg agtctcatat gccatattat     1260

gaatatgaaa ataatgaagt taatttcctg ttgcctttct gtgtcagcca caatatcagg     1320

tctaacccta atccagggat gccagtaaac tgaaggcaat tttaggttgt agaactcaga     1380

ttaattgtag aaaccattaa ttttaattgc tctaattttc atagtaatca taaaaagtat     1440

gcaagtacct aatatataaa ctcaattgac actgtatctg tagaagtaaa tttttaatgg     1500

ctggttaatt atatcactac attttattgc aatatagtac tcatttaagc acttaaaaat     1560

ggaaggtgta caaagattaa attaagacac ggtaaattga ctaaatattt ggtttttata     1620

taaataaagg tcataaccac accgttgaca tgtaatactg ttataataca acagttaaac     1680

ttgtgagtct aaaaaaaaaa aaaaa                                           1705


<210>  741
<211>  14100
<212>  DNA
<213>  homo sapiens

<400>  741
ggcgcggtac aggagcagca ctgccggcgg gggcgggtgc cagggacttg gaggtggagg       60

ggacgcggcg gtactctggc gtcttccgac ttcgactcct taccttaaaa gatgctggag      120

tcatatgtaa ctccaatttt aatgagctat gtgaatcgct acatcaagaa cttaaagccg      180

tcggatctac agctttcact atggggtgga gacgtggtac tcagcaagct cgagttaaag      240

ttggatgtgc tggaacagga actgaaatta ccattcactt ttttaagtgg acatattcat      300

gaattgagga ttcatgtacc atggacaaaa ctgggttcag aaccagtggt aattaccatc      360

aatactatgg aatgcatttt gaaacttaag gatgggatac aggatgacca tgaaagctgt      420

ggttctaatt ctaccaaccg tagtactgct gagagcacaa aatcatcaat caaaccgcgg      480

agaatgcagc aggctgctcc tacagatcct gacttaccac caggttatgt gcagagtctg      540

attagacgag ttgtaaataa tgtaaacatt gtgataaata atctcatact aaaatatgtt      600

gaagatgata tcgtcctttc cgtcaatatc acttctgcag aatgttatac agtaggtgaa      660

ttatgggatc gtgcattcat ggatatttct gcaactgatt tggtgctgag aaaggttatc      720

aatttttctg actgtacagt ttgtcttgat aaacggaatg ccagtggtaa aatagaattt      780

taccaggatc ctttattata caaatgttcc ttcagaactc gtcttcattt tacatatgaa      840

aacctaaatt ccaagatgcc atctgttatt aaaattcata ctttagtgga aagtttgaaa      900

ctttctatca cagatcaaca actgcctatg tttattcgta taatgcaact tggaattgct      960

ctttactatg gagaaatagg caattttaaa gaaggcgaaa tagaggacct tacttgtcat     1020

aataaagata tgctaggaaa cattacaggt tctgaagatg aaacaagaat agatatgcaa     1080

tatcctgctc agcataaagg tcaagagtta tattcacagc aagatgagga gcagccacag     1140

ggatgggtgt catgggcctg gtcctttgtg cctgcaattg tgagttatga cgatggcgag     1200

gaagactttg ttgggaacga tcctgcatca accatgcatc aacaaaaagc acagactttg     1260

aaggatccta ttgtttctat aggattttat tgcacaaagg caacggtgac tttcaaactc     1320

acagaaatgc aagttgagag tagttattac agtccacaga aagtaaaatc taaagaagta     1380

ttgtgttggg aacaagaagg aactacagtt gaggccctta tgatgggaga acctttcttt     1440

gattgccaga ttgggtttgt tggttgcaga gccatgtgcc ttaaaggaat tatgggtgtt     1500

aaagattttg aagagaatat gaatagaagt gaaactgaag cctgtttctt catttgtggt     1560

gacaatttga gtacgaaagg tttcacatac cttacaaatt cattgtttga ttaccgaagc     1620

ccagaaaata atggtactcg cgcagaattt atcttggatt caactcatca taaggagaca     1680

tacactgaga tagctggaat gcaacggttt ggggcttttt atatggatta cctgtataca     1740

atggagaaca ctagtggcaa aggttccaca aatcaacaag acttttcttc agggaaaagt     1800

gaagatttgg gaacagttca ggagaagtcc accaaaagcc ttgttatagg tcctcttgat     1860

tttcgtttgg atagcagtgc ggtgcatagg attttgaaaa tgattgtgtg tgccttggaa     1920

catgaatatg aaccatatag caggctaaaa tcagatatta aggatgaaaa tgaaacaata     1980

ctgaatcctg aagaggtggc tcttctggag gaatatattc ctactcgaca tacaagtgtt     2040

actctcctca aatgtacctg cacaatttcc atggctgaat tcaacttgct ggaccattta     2100

ctacctgtca ttatgggaga aaagaactca agtaacttca tgaatactac aaacttccag     2160

tctcttcggc ctttgccatc cattcgaata ttggtggata aaattaatct ggaacattca     2220

gtgccaatgt atgctgaaca gttggtgcat gtggtcagca gccttactca accttctgat     2280

aacctgcttc attattgtta tgtacactgc tatcttaaga tatttggttt ccaggcagga     2340

ctgacgtctt tggattgcag tggatcttac tgcttacctg taccagttat tccctctttc     2400

agcactgctc tttatgggaa acttctgaaa ctccccacat gctggaccaa aagatctcag     2460

attgctataa ctgaaggtat atttgaactt ccaaatctca caattcaagc tacaagagca     2520

cagacacttc tcttgcaagc aatatatcaa agttggtctc atcttggaaa tgtcagctct     2580

tccgcagtga ttgaagcttt gataaatgaa atcttcctaa gtataggtgt gaaatctaag     2640

aatcccctgc caactcttga gggctcaatc cagaatgttg aattgaagta ctgcagcaca     2700

tcattggtca aatgtgcctc tgggaccatg ggatcaataa aaatttgtgc caaagcccca     2760

gttgatagtg gaaaagagaa gttgattccc ttgcttcagg gtccttctga cactaaagac     2820

cttcatagca ccaagtggct caatgagagt agaaagccag agtctctctt agctccagat     2880

ttgatggcct tcacaatcca agttccacaa tatattgact actgccacaa ttccggtgct     2940

gtacttcttt gcagtataca aggactagca gttaatattg acccaatctt atatacgtgg     3000

ctcatctatc agcctcagaa acgaacaagt agacatatgc aacagcagcc tgtggtagct     3060

gttcctcttg ttatgccagt ttgtagaagg aaagaggatg aggtgtctat tggaagtgcc     3120

cccttggcaa agcagcaatc atatcaggcc tctgaatatg ccagcagccc tgtaaaaaca     3180

aaaacggtaa cagaatcccg cccattgtca gttcctgtta aagccatgtt gaatatatct     3240

gaaagctgta gaagtcctga agaaagaatg aaggaattta ttggaattgt ttggaatgca     3300

gtgaagcatc tcacactaca gcttgaagta caatcttgtt gtgtgtttat tccaaatgat     3360

agcctgcctt ccccaagtac aattgtatct ggtgacattc ctggaacagt aagaagttgg     3420

taccatggac aaaccagcat gccgggaaca cttgtcctct gtttgcctca aataaagatt     3480

attagtgctg ggcacaagta tatggaacct ctgcaggaga ttccatttgt tatcccacga     3540

cccatccttg aagaaggtga tgcttttcct tggacgatca gcttgcataa tttcagcata     3600

tatacccttc ttggaaaaca agtgacactt tgcctagtgg aacctatggg ttgcacctcc     3660

actctagctg tcacgtctca aaaactgctt gctacgggac ctgatacacg acattcattt     3720

gttgtctgtc tccatgttga cctagagtca ctagagataa aatgctctaa tccccaggtc     3780

cagctcttct atgaactaac tgatatcatg aataaggtct ggaacaagat tcagaagaga     3840

ggcaatctca acctatctcc aacctctcca gagaccatgg cagggcctgt tcctacttct     3900

ccagttagaa gcagtatagg cacagctcct ccagatacca gcacatgcag cccatctgct     3960

gacattggga ctactactga gggagattct atacaagcag gtgaggaatc accattctca     4020

gattctgtga ccttggaaca aactacaagt aatattggag gaaccagtgg acgtgttagt     4080

ttatggatgc agtgggtgct tcccaaaatt actataaagc tctttgctcc agatcctgaa     4140

aataaaggca cagaggtttg tatggtcagt gaactagaag atctcagtgc ttccatagat     4200

gtccaggatg tatataccaa agtgaaatgt aaaatagaga gtttcaatat tgatcactat     4260

agaagcagcc ttggggaaga gtgttggtct ttggggcaat gtggaggtgt cttcctttcc     4320

tgtactgaca agctgaacag acgcaccttg ttggttcgac ccatcagcaa gcaggaccct     4380

ttcagtaatt gctctggctt ctttccttct acaactacaa aacttctaga tggcactcat     4440

cagcagcatg gattcctctc tctgacatac acaaaagctg taacaaaaaa tgtccgccac     4500

aagttaacat caagaaatga gcgaagaagt tttcataagt tatctgaagg cctaatggat     4560

ggttctcctc attttcttca tgaaattctt ctttcagcac aagcttttga tattgttctt     4620

tattttcctt tacttaatgc cattgcaagt atatttcaag caaaactacc aaagacccaa     4680

aaagagaaaa gaaaatctcc tggtcagccc atgaggaccc atacactgac atcccgcaat     4740

ttacctttga tttatgtcaa cacaagtgta atcagaattt ttattccaaa aacagaagaa     4800

atgcagccaa ctgttgaagc taatcaggca gcaaaagaag acactgtggt tttgaagatt     4860

ggctctgttg ccatggctcc ccaggctgac aatccccttg gcagatctgt ccttaggaaa     4920

gatatttacc agagagcctt gaacttagga attcttcgag atcctggatc agaaatcgaa     4980

gacagacaat accaaataga tctgcagtcc atcaatattg gtactgcaca gtggcatcaa     5040

ctaaaaccag agaaggaaag tgtctcagga ggggtggtaa cagagactga aaggaattct     5100

caaaatccag cccttgagtg gaatatggcc agcagcatac ggcggcatca agaaaggaga     5160

gcaattttga cccccgtttt gacagatttt tctgtccgaa taactggagc acctgctgtc     5220

attttcacca aagtagtttc tccagaaaat ttgcatactg aggagatttt agtgtgtggc     5280

cattccttag aagtgaatat aaccacaaac ctggacttct tcctaagtgt ggctcaagtt     5340

caactcttac atcagttaat agtagcaaat atgactggac tggaaccatc aaacaaggct     5400

gcagagatct ctaaacaaga acagaaaaaa gtggatatat ttgatggagg catggctgaa     5460

acctcatctc gctacagtgg tgctcaggat agtggaattg gcagtgacag tgttaaaatc     5520

agaatagtgc aaatagagca gcacagtggt gccagtcagc atcgcattgc ccgtccctca     5580

cgccagtcat caattgtaaa aaatctaaat tttattccct ttgacatatt tattactgca     5640

agtagaatct cactaatgac ctattcctgt atggccttat ccaaatcgaa atcacaagaa     5700

cagaagaata atgaaaaaac agacaagagt tcattaaatc tcccagaagt tgattcagat     5760

gttgctaagc ccaaccaggc atgtatttcc acggtgacag cagaagatct cttaaggagc     5820

agcatttctt ttccttcagg gaaaaaaata ggggtcctct ctcttgaaag tcttcatgca     5880

tccacaaggt catctgctag acaagcactt ggtataacta ttgttcggca gcctggtcga     5940

agaggaactg gtgacttaca gctagagcct tttctgtact ttattgtgtc ccagccttcc     6000

ttgcttctga gttgtcacca cagaaagcag cgagtggaag tatccatttt tgatgctgtg     6060

cttaaagggg tggcctctga ttacaaatgt atagatcctg ggaagactct gcctgaagcc     6120

cttgattatt gcactgtttg gctacagaca gtgcctggag aaatagacag caaaagtggt     6180

attccacctt cctttataac actacagatt aaagactttc tgaatggacc agcggatgtc     6240

aatttggata tatcaaagcc tttgaaagca aacctgagtt tcaccaaact ggatcagata     6300

aacctttttt taaagaagat aaaaaatgca cacagtttgg cacatagtga agagacttca     6360

gccatgtcca acaccatggt gaataaggat gatcttccag tctccaaata ttaccgtgga     6420

aagttgtcta aacccaaaat tcatggtgat ggagtgcaaa agatttcagc tcaagaaaac     6480

atgtggagag ctgtttcctg ctttcaaaaa atttctgttc aaactactca gattgtgatc     6540

tccatggaaa ctgtacccca taccagcaaa ccatgcctgt tagcatctct ctcaaacctc     6600

aatggaagcc ttagtgtcaa ggcaacacaa aaagtacctg gcataattct tgggtcatca     6660

tttctactca gtataaacga ttttctcctt aaaacaagtc tcaaagaaag aagccgcatt     6720

ctgataggac catgttgtgc tactgccaat ctggaagcta agtggtgtaa acacagcggg     6780

aatccaggcc cagaacaatc cataccaaaa atatccattg acttaagagg aggtctacta     6840

caggtcttct ggggtcaaga acatttgaat tgtttagttc ttctacatga attactcaat     6900

ggatacctta atgaggaggg aaattttgaa gtacaagttt ctgaaccagt gcctcaaatg     6960

tcatctcctg tggaaaagaa tcagacattt aaaagtgaac aaagttcaga tgacctacgg     7020

acaggtctat ttcagtatgt acaggatgct gaatctttga aattgcctgg ggtctatgaa     7080

gtcttatttt ataatgaaac tgaagattgc ccagggatga tgttatggag atatccagaa     7140

cctagagtac tcacccttgt acgaataact cctgtacctt ttaacaccac agaggatcca     7200

gatattagca cagcagacct tggtgatgtg ctacaggttc cttgtagctt ggaatactgg     7260

gatgaactcc agaaggtttt tgttgcattt agagaattta atctgtctga aagcaaagtt     7320

tgtgaactgc agttgccgga tatcaatctc gtgaatgacc agaagaaatt agtatcttca     7380

gatctttgga gaattgtctt gaacagcagt caaaatggag ctgatgacca aagctctgca     7440

agtgagtctg gttctcaaag cacttgtgat ccacttgtga ctccaacagc cctggctgcc     7500

tgtaccagag ttgactcctg ctttacccca tggtttgtcc catccctttg cgtttctttc     7560

cagtttgctc acctggaatt ccatctttgt catcaccttg accaactagg cacagctgca     7620

ccacagtacc tacagccatt tgtttccgac agaaatatgc catctgaact agaatacatg     7680

attgtttcct tcagagaacc acacatgtat cttcgacagt ggaataatgg ttctgtctgt     7740

caggagatcc agttcttagc tcaagcagac tgtaaacttc tagagtgcag aaatgtcact     7800

atgcaaagtg tggtgaaacc cttcagcatc ttcgggcaga tggcagtttc cagcgatgta     7860

gtggaaaagc tgcttgactg caccgtgata gttgattctg tatttgtaaa ccttggacag     7920

catgtagtcc attcactaaa cactgcaata caagcttggc aacagaacaa atgccctgag     7980

gtagaggagt tggtcttcag ccattttgtg atctgtaatg acacacagga gacactgcgg     8040

tttggccagg tggatactga tgaaaatatt ctgctggcga gtctccacag tcaccagtac     8100

agctggcgct ctcacaaatc cccacagctg ttacacatct gtattgaagg ttggggcaac     8160

tggcgttggt cagagccttt cagtgtggac catgccggga cttttattag aacaattcag     8220

tacaggggtc gaactgcttc tctcatcatc aaggttcagc aactcaatgg agtacaaaaa     8280

cagattatca tctgtggaag acagatcatc tgtagttact tgtctcaaag catagaacta     8340

aaagtcgttc agcattacat tggtcaagat ggacaagctg tagttcggga acattttgac     8400

tgcctcacag ccaaacagaa attgccttcg tacatactag aaaacaatga actgacggag     8460

ctgtgtgtga aggccaaagg agatgaagac tggtcaagag atgtgtgcct ggaatccaaa     8520

gcccctgagt acagcattgt cattcaggtg ccatcttcaa acagttccat tatttatgtc     8580

tggtgcacag ttttgacttt agaacccaac tctcaagtgc aacaacgaat gattgtgttc     8640

agccctcttt ttatcatgag gagtcatctt ccagacccca ttatcataca tttggagaaa     8700

aggagtctgg gattgagtga aacacaaatt attccaggaa aagggcagga aaaaccactg     8760

caaaacatag aacctgacct tgtacatcac ctgacattcc aagcaagaga agaatatgat     8820

ccttcagatt gtgcagttcc catctcaaca tccctcatta agcaaatagc cactaaggta     8880

caccctggag gcacagttaa tcagatcctt gacgaattct atgggccaga aaagtcgctt     8940

caacccatat ggccctataa taagaaggat tctgacagga atgaacagct aagtcagtgg     9000

gatagcccaa tgcgagtgaa gctgtcaatc tggaagccat atgttagaac tttgttgata     9060

gaacttctgc cctgggccct gcttatcaat gaatccaaat gggacctctg gctatttgaa     9120

ggagagaaaa ttgttctaca ggttcctgct ggcaaaatta ttattcctcc taattttcag     9180

gaagcttttc aaattggaat atactgggca aatacaaaca ctgtgcacaa gtcagtagca     9240

attaaactgg tccataacct gacatctcca aagtggaaag atggaggtaa tggtgaagtt     9300

gtgacactgg atgaagaagc gtttgttgat actgaaataa gacttggtgc ttttccagga     9360

catcagaagt tatgtcagtt ctgcatttcc tccatggtac agcaaggtat acaaattatt     9420

cagattgaag acaagactac aataatcaat aatacaccat atcaaatatt ttataaacca     9480

cagctatctg tctgcaatcc ccattctgga aaggagtatt ttcgtgttcc agacagtgct     9540

acttttagca tttgcccagg tggagagcag cctgctatga aatccagctc ccttccttgc     9600

tgggacttga tgcctgacat cagtcagtca gtactggatg catccctgct tcagaaacag     9660

atcatgctgg gcttttctcc tgccccaggt gctgacagct cacagtgctg gagcctgcca     9720

gctatagtta gaccagagtt tcccagacag agtgtggcag tacccctcgg gaatttccgg     9780

gaaaatggat tctgtaccag ggctatagtg ctgacatatc aagaacacct cggagtgact     9840

tatttaaccc tctcagaaga ccctagtcct cgagtaatta tccacaatag atgtccagta     9900

aaaatgctta taaaggaaaa cattaaagat attccaaagt ttgaggttta ttgcaaaaaa     9960

attccctccg agtgctcaat tcatcatgag ctgtatcatc agatttccag ttatccggac    10020

tgcaagacca aagacttact tccaagccta cttttgagag ttgaacctct agatgaagta    10080

acaactgagt ggagtgatgc cattgacatc aacagtcagg gaacacaggt tgtgttcctg    10140

actggctttg gctatgtgta tgtggatgtt gtacatcagt gtggcacagt cttcatcact    10200

gtggccccag aaggaaaagc aggacctatt ttaaccaata ccaacagagc gccagagaag    10260

attgttacat ttaaaatgtt catcactcag ttaagcctgg cagtgtttga tgacctcacc    10320

caccacaaag catcagctga gcttctgaga ctcacactgg acaacatttt tctctgtgtg    10380

gccccgggag ctggtcccct ccctggggaa gagcctgtgg ctgcgttgtt tgaactttac    10440

tgtgtggaga tctgctgtgg ggacctgcag ctagacaacc agctttataa caagtccaat    10500

ttccactttg ctgtcttagt ctgccaggga gaaaaagcag aacccattca gtgttccaaa    10560

atgcagagtc tcctcatatc caacaaagag ttggaagaat acaaggaaaa atgttttatc    10620

aaactttgca tcaccttaaa tgaaggcaag agcatcctct gtgatattaa tgagttcagc    10680

tttgaattaa aacctgctcg gttatacgtg gaagacacat ttgtatacta catcaagact    10740

ttgtttgaca cctaccttcc taacagcagg ttggctggtc actccacaca cctctccggg    10800

ggtaaacagg tgttgcccat gcaggtcaca cagcacgcca gggccttggt gaatcctgtg    10860

aagttacgga aactggtgat ccagccagta aatttgctcg tcagcatcca cgcttccctc    10920

aagctgtaca tagcctcaga ccacactcct ctctccttct cggtgtttga aagaggaccc    10980

atcttcacca ctgcgaggca gcttgtgcac gccctggcaa tgcactatgc cgctggggcc    11040

ctttttagag caggctgggt agttgggtct ctggatattc ttggcagccc tgcaagcctg    11100

gtgagaagca tcgggaacgg ggtcgccgac ttcttcaggc ttccgtatga ggggctgacc    11160

cggggccctg gagccttcgt gagtggcgtc tccagaggga ccacatcgtt tgtaaagcac    11220

atctccaaag gtaccctcac atccatcacc aacctcgcca caagcctggc ccggaacatg    11280

gaccggctct cactggatga ggagcactac aaccggcagg aggagtggcg gcggcagctc    11340

cccgagagcc tgggcgaggg gcttcgacag ggcctgtccc ggctgggcat cagcctgctt    11400

ggtgcaattg ctggtatagt tgatcagccg atgcagaact tccagaaaac atctgaggca    11460

caggcttcag caggacacaa ggccaagggt gtcatctcgg gtgtggggaa aggaatcatg    11520

ggggtgttca caaagcccat cggaggagct gctgagctgg tgtcacagac tggctatggt    11580

attttacatg gagctggact ttctcagctt cccaaacagc gccatcagcc aagtgatcta    11640

catgctgacc aggctccaaa cagccatgtc aaatatgtct ggaaaatgct tcagtctctg    11700

ggcagaccag aagtccacat ggccctggac gtggttctgg tgaggggctc aggccaggag    11760

catgaagggt gcttgctgct gacatcagaa gtgctcttcg tggtgagtgt cagtgaggac    11820

acacagcagc aggccttccc cgtcacagaa atcgactgtg cacaggacag caagcagaac    11880

aacttactca cagtgcagct caagcagcca agagtggcct gtgatgtgga ggtagatgga    11940

gtccgagaga gactgtcaga gcaacagtac aacagactgg tggactacat cacaaagaca    12000

tcttgtcacc tggcccccag ctgttcttcc atgcaaatac catgccctgt ggtggctgca    12060

gaacctcccc cctccactgt taaaacatac cattacctgg ttgatccaca ttttgctcag    12120

gtcttcctta gtaaatttac catggtgaaa aataaagccc tgaggaaagg gtttccttga    12180

gtcccctctg aggtgtttat tcctgcttgt gtgatttagt ttttgggttt ctttgagaca    12240

gggtctcact gcattgccct tgctgacctc aaattctggg gttcaagcaa tcctcccacc    12300

tcaacccaca agtagctacg actgcaagca cctgccacca taaagggctg cattttgcca    12360

ccataaaggg ctgcattttt ttaaaaagcc taggcagctc taacatcatc tgatatggac    12420

acaaggccaa cagtttcctt atttacatcc ttacctctaa aagatacttc aaagtgacaa    12480

aaacgtgttc cttccccact tagagacaat gattaacagg gccctatatg ttcttaccac    12540

atacagagga tgcatttatt tttgctctat gacacttgca aaaatctcta ctgtaattaa    12600

tttgggtcta ttattaactc tctgttccat catagaatgt ggccaggcct tacaatggag    12660

agccagagtt aaaacttcaa gttgcatctg tttttgggct gagtcaccac ctttgcctca    12720

tgctcctttg tctgcaaagg cctaggattc tttctttaaa tgaaatgctt aggactttgt    12780

ggcttgttac atttgtcatt taactgcagt gctattcttt gaaagctgct atgtgtattt    12840

tctctgaagt ctgcatttta ctaaaattta caacagtctg atgattgatt gattactgtc    12900

caggtacatt ttagaaaaag tgttcttctt ccagtttgtt ttactaagca aactttgagt    12960

aaatcctttg tcctatattg aatccagtcc caaagtgttc aggtgagttt ctctagttcc    13020

ataaacaaaa catacatagt gggaactccc tggtatgcca tagagcacac aagaacccca    13080

atattaatgc taacaattat accagtccat tttgtttatt ctgtggaatt gacttgacaa    13140

agcatgaaga tattcccagt gtctgtctga taatattttg catctaagaa tgggtttgac    13200

tcaagatctt gggttaccaa gatgtcttaa atgttcagta aatatctttc ttacagtcca    13260

gtagcttaga gcatgtttgc tgattgatat tacatttaaa cttggggcta cagcttgtta    13320

cctagaattt tgagatacta agagaatgca attttaaatg cccactggtt ttatttgttt    13380

tggagagagg gtctcattct gtcacccagg ctagagtaca gtgggaacag tcatggctca    13440

ctgcagctta agctcactgc ctgggctcaa gtgatcttac tccagcctcc caagcagctg    13500

ggactacacc accacaggta tgcaccacca tacctggctg atttttaaaa ttttttctag    13560

agatgaggtc tcactatgtt gcccagctgg tctcatactc ctcagttcac gcattcctcc    13620

cacctccacc tcccaaactg ctgggattac aggtgtgagc caccatgccc aacacccact    13680

gatctttaac tctcacatgt tgggcataag aagtcactat ataattgtta ctggaaagca    13740

agacttaacg aacaattctg actatgaaaa atgtctcttt cagtttgttc tgtaaatatt    13800

tagaaaagtg acagctgtca acctcagagt aactatttct aaaaatgtaa atatgtatta    13860

atccttgtat cttttatggt aattttgcat attgatatga attatataaa attgtttaaa    13920

ataaaaggtg tccttgaatt actgaccacc catagatgtc tactgttacc aggttttaca    13980

atgcaaattt tcactaatac ctgggtttaa tacagctcac atcactgaat gttacacatg    14040

agtttaaatg ggtaatatac aggttttgtt ataataaagt tactgattaa attagctttg    14100


<210>  742
<211>  3546
<212>  DNA
<213>  homo sapiens

<400>  742
gctgacgcgc gctgacgcgc ggagacttta ggtgcatgtt ggcagcggca gcgcaagcca       60

cataaacaaa ggcacattgg cggccagggc cagtccgccc ggcggctcgc gcacggctcc      120

gcggtccctt ttgcctgtcc agccggccgc ctgtccctgc tccctccctc cgtgaggtgt      180

ccgggttccc ttcgcccagc tctcccaccc ctacccgacc ccggcgcccg ggctcccaga      240

gggaactgca cttcggcaga gttgaatgaa tgaagagaga cgcggagaac tcctaaggag      300

gagattggac aggctggact ccccattgct tttctaaaaa tcttggaaac tttgtccttc      360

attgaattac gacactgtcc acctttaatt tcctcgaaaa cgcctgtaac tcggctgaag      420

ccatgccttg tgttcaggcg cagtatgggt cctcgcctca aggagccagc cccgcttctc      480

agagctacag ttaccactct tcgggagaat acagctccga tttcttaact ccagagtttg      540

tcaagtttag catggacctc accaacactg aaatcactgc caccacttct ctccccagct      600

tcagtacctt tatggacaac tacagcacag gctacgacgt caagccacct tgcttgtacc      660

aaatgcccct gtccggacag cagtcctcca ttaaggtaga agacattcag atgcacaact      720

accagcaaca cagccacctg cccccccagt ctgaggagat gatgccgcac tccgggtcgg      780

tttactacaa gccctcctcg cccccgacgc ccaccacccc gggcttccag gtgcagcaca      840

gccccatgtg ggacgacccg ggatctctcc acaacttcca ccagaactac gtggccacta      900

cgcacatgat cgagcagagg aaaacgccag tctcccgcct ctccctcttc tcctttaagc      960

aatcgccccc tggcaccccg gtgtctagtt gccagatgcg cttcgacggg cccctgcacg     1020

tccccatgaa cccggagccc gccggcagcc accacgtggt ggacgggcag accttcgctg     1080

tgcccaaccc cattcgcaag cccgcgtcca tgggcttccc gggcctgcag atcggccacg     1140

cgtctcagct gctcgacacg caggtgccct caccgccgtc gcggggctcc ccctccaacg     1200

aggggctgtg cgctgtgtgt ggggacaacg cggcctgcca acactacggc gtgcgcacct     1260

gtgagggctg caaaggcttc tttaagcgca cagtgcaaaa aaatgcaaaa tacgtgtgtt     1320

tagcaaataa aaactgccca gtggacaagc gtcgccggaa tcgctgtcag tactgccgat     1380

ttcagaagtg cctggctgtt gggatggtca aagaagtggt tcgcacagac agtttaaaag     1440

gccggagagg tcgtttgccc tcgaaaccga agagcccaca ggagccctct cccccttcgc     1500

ccccggtgag tctgatcagt gccctcgtca gggcccatgt cgactccaac ccggctatga     1560

ccagcctgga ctattccagg ttccaggcga accctgacta tcaaatgagt ggagatgaca     1620

cccagcatat ccagcaattc tatgatctcc tgactggctc catggagatc atccggggct     1680

gggcagagaa gatccctggc ttcgcagacc tgcccaaagc cgaccaagac ctgctttttg     1740

aatcagcttt cttagaactg tttgtccttc gattagcata caggtccaac ccagtggagg     1800

gtaaactcat cttttgcaat ggggtggtct tgcacaggtt gcaatgcgtt cgtggctttg     1860

gggaatggat tgattccatt gttgaattct cctccaactt gcagaatatg aacatcgaca     1920

tttctgcctt ctcctgcatt gctgccctgg ctatggtcac agagagacac gggctcaagg     1980

aacccaagag agtggaagaa ctgcaaaaca agattgtaaa ttgtctcaaa gaccacgtga     2040

ctttcaacaa tggggggttg aaccgcccca attatttgtc caaactgttg gggaagctcc     2100

cagaacttcg taccctttgc acacaggggc tacagcgcat tttctacctg aaattggaag     2160

acttggtgcc accgccagca ataattgaca aacttttcct ggacacttta cctttctaag     2220

acctcctccc aagcacttca aaggaactgg aatgataatg gaaactgtca agagggggca     2280

agtcacatgg gcagagatag ccgtgtgagc agtctcagct caagctgccc cccatttctg     2340

taaccctcct agcccccttg atccctaaag aaaacaaaca aacaaacaaa aactgttgct     2400

atttcctaac ctgcaggcag aacctgaaag ggcattttgg ctccggggca tcctggattt     2460

agaacatgga ctacacacaa tacagtggta taaacttttt attctcagtt taaaaatcag     2520

tttgttgttc agaagaaaga ttgctataat gtataatggg aaatgtttgg ccatgcttgg     2580

ttgttgcagt tcagacaaat gtaacacaca cacacataca cacacacaca cacacacaga     2640

gacacatctt aaggggaccc acaagtattg ccctttaaca agacttcaaa gttttctgct     2700

gtaaagaaag ctgtaatata tagtaaaact aaatgttgcg tgggtggcat gagttgaaga     2760

aggcaaaggc ttgtaaattt acccaatgca gtttggcttt ttaaattatt ttgtgcctat     2820

ttatgaataa atattacaaa ttctaaaaga taagtgtgtt tgcaaaaaaa aagaaaataa     2880

atacataaaa aagggacaag catgttgatt ctaggttgaa aatgttatag gcacttgcta     2940

cttcagtaat gtctatatta tataaatagt atttcagaca ctatgtagtc tgttagattt     3000

tataaagatt ggtagttatc tgagcttaaa cattttctca attgtaaaat aggtgggcac     3060

aagtattaca catcagaaaa tcctgacaaa agggacacat agtgtttgta acaccgtcca     3120

acattccttg tttgtaagtg ttgtatgtac cgttgatgtt gataaaaaga aagtttatat     3180

cttgattatt ttgttgtcta aagctaaaca aaacttgcat gcagcagctt ttgactgttt     3240

ccagagtgct tataatatac ataactccct ggaaataact gagcactttg aatttttttt     3300

atgtctaaaa ttgtcagtta atttattatt ttgtttgagt aagaatttta atattgccat     3360

attctgtagt atttttcttt gtatatttct agtatggcac atgatatgag tcactgcctt     3420

tttttctatg gtgtatgaca gttagagatg ctgatttttt ttctgataaa ttctttcttt     3480

gagaaagaca attttaatgt ttacaacaat aaaccatgta aatgaacaga aaaaaaaaaa     3540

aaaaaa                                                                3546


<210>  743
<211>  3546
<212>  DNA
<213>  homo sapiens

<400>  743
gctgacgcgc gctgacgcgc ggagacttta ggtgcatgtt ggcagcggca gcgcaagcca       60

cataaacaaa ggcacattgg cggccagggc cagtccgccc ggcggctcgc gcacggctcc      120

gcggtccctt ttgcctgtcc agccggccgc ctgtccctgc tccctccctc cgtgaggtgt      180

ccgggttccc ttcgcccagc tctcccaccc ctacccgacc ccggcgcccg ggctcccaga      240

gggaactgca cttcggcaga gttgaatgaa tgaagagaga cgcggagaac tcctaaggag      300

gagattggac aggctggact ccccattgct tttctaaaaa tcttggaaac tttgtccttc      360

attgaattac gacactgtcc acctttaatt tcctcgaaaa cgcctgtaac tcggctgaag      420

ccatgccttg tgttcaggcg cagtatgggt cctcgcctca aggagccagc cccgcttctc      480

agagctacag ttaccactct tcgggagaat acagctccga tttcttaact ccagagtttg      540

tcaagtttag catggacctc accaacactg aaatcactgc caccacttct ctccccagct      600

tcagtacctt tatggacaac tacagcacag gctacgacgt caagccacct tgcttgtacc      660

aaatgcccct gtccggacag cagtcctcca ttaaggtaga agacattcag atgcacaact      720

accagcaaca cagccacctg cccccccagt ctgaggagat gatgccgcac tccgggtcgg      780

tttactacaa gccctcctcg cccccgacgc ccaccacccc gggcttccag gtgcagcaca      840

gccccatgtg ggacgacccg ggatctctcc acaacttcca ccagaactac gtggccacta      900

cgcacatgat cgagcagagg aaaacgccag tctcccgcct ctccctcttc tcctttaagc      960

aatcgccccc tggcaccccg gtgtctagtt gccagatgcg cttcgacggg cccctgcacg     1020

tccccatgaa cccggagccc gccggcagcc accacgtggt ggacgggcag accttcgctg     1080

tgcccaaccc cattcgcaag cccgcgtcca tgggcttccc gggcctgcag atcggccacg     1140

cgtctcagct gctcgacacg caggtgccct caccgccgtc gcggggctcc ccctccaacg     1200

aggggctgtg cgctgtgtgt ggggacaacg cggcctgcca acactacggc gtgcgcacct     1260

gtgagggctg caaaggcttc tttaagcgca cagtgcaaaa aaatgcaaaa tacgtgtgtt     1320

tagcaaataa aaactgccca gtggacaagc gtcgccggaa tcgctgtcag tactgccgat     1380

ttcagaagtg cctggctgtt gggatggtca aagaagtggt tcgcacagac agtttaaaag     1440

gccggagagg tcgtttgccc tcgaaaccga agagcccaca ggagccctct cccccttcgc     1500

ccccggtgag tctgatcagt gccctcgtca gggcccatgt cgactccaac ccggctatga     1560

ccagcctgga ctattccagg ttccaggcga accctgacta tcaaatgagt ggagatgaca     1620

cccagcatat ccagcaattc tatgatctcc tgactggctc catggagatc atccggggct     1680

gggcagagaa gatccctggc ttcgcagacc tgcccaaagc cgaccaagac ctgctttttg     1740

aatcagcttt cttagaactg tttgtccttc gattagcata caggtccaac ccagtggagg     1800

gtaaactcat cttttgcaat ggggtggtct tgcacaggtt gcaatgcgtt cgtggctttg     1860

gggaatggat tgattccatt gttgaattct cctccaactt gcagaatatg aacatcgaca     1920

tttctgcctt ctcctgcatt gctgccctgg ctatggtcac agagagacac gggctcaagg     1980

aacccaagag agtggaagaa ctgcaaaaca agattgtaaa ttgtctcaaa gaccacgtga     2040

ctttcaacaa tggggggttg aaccgcccca attatttgtc caaactgttg gggaagctcc     2100

cagaacttcg taccctttgc acacaggggc tacagcgcat tttctacctg aaattggaag     2160

acttggtgcc accgccagca ataattgaca aacttttcct ggacacttta cctttctaag     2220

acctcctccc aagcacttca aaggaactgg aatgataatg gaaactgtca agagggggca     2280

agtcacatgg gcagagatag ccgtgtgagc agtctcagct caagctgccc cccatttctg     2340

taaccctcct agcccccttg atccctaaag aaaacaaaca aacaaacaaa aactgttgct     2400

atttcctaac ctgcaggcag aacctgaaag ggcattttgg ctccggggca tcctggattt     2460

agaacatgga ctacacacaa tacagtggta taaacttttt attctcagtt taaaaatcag     2520

tttgttgttc agaagaaaga ttgctataat gtataatggg aaatgtttgg ccatgcttgg     2580

ttgttgcagt tcagacaaat gtaacacaca cacacataca cacacacaca cacacacaga     2640

gacacatctt aaggggaccc acaagtattg ccctttaaca agacttcaaa gttttctgct     2700

gtaaagaaag ctgtaatata tagtaaaact aaatgttgcg tgggtggcat gagttgaaga     2760

aggcaaaggc ttgtaaattt acccaatgca gtttggcttt ttaaattatt ttgtgcctat     2820

ttatgaataa atattacaaa ttctaaaaga taagtgtgtt tgcaaaaaaa aagaaaataa     2880

atacataaaa aagggacaag catgttgatt ctaggttgaa aatgttatag gcacttgcta     2940

cttcagtaat gtctatatta tataaatagt atttcagaca ctatgtagtc tgttagattt     3000

tataaagatt ggtagttatc tgagcttaaa cattttctca attgtaaaat aggtgggcac     3060

aagtattaca catcagaaaa tcctgacaaa agggacacat agtgtttgta acaccgtcca     3120

acattccttg tttgtaagtg ttgtatgtac cgttgatgtt gataaaaaga aagtttatat     3180

cttgattatt ttgttgtcta aagctaaaca aaacttgcat gcagcagctt ttgactgttt     3240

ccagagtgct tataatatac ataactccct ggaaataact gagcactttg aatttttttt     3300

atgtctaaaa ttgtcagtta atttattatt ttgtttgagt aagaatttta atattgccat     3360

attctgtagt atttttcttt gtatatttct agtatggcac atgatatgag tcactgcctt     3420

tttttctatg gtgtatgaca gttagagatg ctgatttttt ttctgataaa ttctttcttt     3480

gagaaagaca attttaatgt ttacaacaat aaaccatgta aatgaacaga aaaaaaaaaa     3540

aaaaaa                                                                3546


<210>  744
<211>  2184
<212>  DNA
<213>  homo sapiens

<400>  744
tattcttcca aatggaaact gctaattttt gaagcagaag gttgacagct tcagtaagat       60

ctcaagagag cgagaagact ggaatcaggg aaccctactc tggaaactgt cagtcccagg      120

gcactgggga gggctgaggc cgaccatgcc cagcctgctg ctgctgttca cggctgctct      180

gctgtccagc tgggctcagc ttctgacaga cgccaactcc tggtggtcat tagctttgaa      240

cccggtgcag agacccgaga tgtttatcat cggtgcccag cccgtgtgca gtcagcttcc      300

cgggctctcc cctggccaga ggaagctgtg ccaattgtac caggagcaca tggcctacat      360

aggggaggga gccaagactg gcatcaagga atgccagcac cagttccggc agcggcggtg      420

gaattgcagc acagcggaca acgcatctgt ctttgggaga gtcatgcaga taggcagccg      480

agagaccgcc ttcacccacg cggtgagcgc cgcgggcgtg gtcaacgcca tcagccgggc      540

ctgccgcgag ggcgagctct ccacctgcgg ctgcagccgg acggcgcggc ccaaggacct      600

gccccgggac tggctgtggg gcggctgtgg ggacaacgtg gagtacggct accgcttcgc      660

caaggagttt gtggatgccc gggagcgaga gaagaacttt gccaaaggat cagaggagca      720

gggccgggtg ctcatgaacc tgcaaaacaa cgaggccggt cgcagggctg tgtataagat      780

ggcagacgta gcctgcaaat gccacggcgt ctcggggtcc tgcagcctca agacctgctg      840

gctgcagctg gccgagttcc gcaaggtcgg ggaccggctg aaggagaagt acgacagcgc      900

ggccgccatg cgcgtcaccc gcaagggccg gctggagctg gtcaacagcc gcttcaccca      960

gcccaccccg gaggacctgg tctatgtgga ccccagcccc gactactgcc tgcgcaacga     1020

gagcacgggc tccctgggca cgcagggccg cctctgcaac aagacctcgg agggcatgga     1080

tggctgtgag ctcatgtgct gcgggcgtgg ctacaaccag ttcaagagcg tgcaggtgga     1140

gcgctgccac tgcaagttcc actggtgctg cttcgtcagg tgtaagaagt gcacggagat     1200

cgtggaccag tacatctgta aatagcccgg agggcctgct cccggccccc ctgcactctg     1260

cctcacaaag gtctatatta tataaatcta tataaatcta ttttatattt gtataagtaa     1320

atgggtgggt gctatacaat ggaaagatga aaatggaaag gaagagctta tttaagagac     1380

gctggagatc tctgaggagt ggactttgct ggttctctcc tcttggtggg tgggagacag     1440

ggctttttct ctccctctgg cgaggactct caggatgtag ggacttggaa atatttactg     1500

tctgtccacc acggcctgga ggagggaggt tgtggttgga tggaggagat gatcttgtct     1560

ggaagtctag agtctttgtt ggttagagga ctgcctgtga tcctggccac taggccaaga     1620

ggccctatga aggtggcggg aactcagctt caacctcgat gtcttcaggg tcttgtccag     1680

aatgtagatg ggttccgtaa gaggcctggt gctctcttac tctttcatcc acgtgcactt     1740

gtgcggcatc tgcagtttac aggaacggct ccttccctaa aatgagaagt ccaaggtcat     1800

ctctggccca gtgaccacag agagatctgc acctcccgga cttcaggcct gcctttccag     1860

cgagaattct tcatcctcca cggttcacta gctcctacct gaagaggaaa gggggccatt     1920

tgacctgaca tgtcaggaaa gccctaaact gaatgtttgc gcctgggctg cagaagccag     1980

ggtgcatgac caggctgcgt ggacgttata ctgtcttccc ccacccccgg ggaggggaag     2040

cttgagctgc tgctgtcact cctccaccga gggaggcctc acaaaccaca ggacgctgca     2100

acgggtcagg ctggcgggcc cggcgtgctc atcatctctg ccccaggtgt acggtttctc     2160

tctgacatta aatgcccttc atgg                                            2184


<210>  745
<211>  2251
<212>  DNA
<213>  homo sapiens

<400>  745
gaccattagc aggcacccag gcctgtcttt ggctcggaaa cggtggcccc caatgtagcc       60

tagtttgaac ctaggaactg caggaccaga gagattccac tggagcctga tggacgggtg      120

acagagggaa ccctactctg gaaactgtca gtcccagggc actggggagg gctgaggccg      180

accatgccca gcctgctgct gctgttcacg gctgctctgc tgtccagctg ggctcagctt      240

ctgacagacg ccaactcctg gtggtcatta gctttgaacc cggtgcagag acccgagatg      300

tttatcatcg gtgcccagcc cgtgtgcagt cagcttcccg ggctctcccc tggccagagg      360

aagctgtgcc aattgtacca ggagcacatg gcctacatag gggagggagc caagactggc      420

atcaaggaat gccagcacca gttccggcag cggcggtgga attgcagcac agcggacaac      480

gcatctgtct ttgggagagt catgcagata ggcagccgag agaccgcctt cacccacgcg      540

gtgagcgccg cgggcgtggt caacgccatc agccgggcct gccgcgaggg cgagctctcc      600

acctgcggct gcagccggac ggcgcggccc aaggacctgc cccgggactg gctgtggggc      660

ggctgtgggg acaacgtgga gtacggctac cgcttcgcca aggagtttgt ggatgcccgg      720

gagcgagaga agaactttgc caaaggatca gaggagcagg gccgggtgct catgaacctg      780

caaaacaacg aggccggtcg cagggctgtg tataagatgg cagacgtagc ctgcaaatgc      840

cacggcgtct cggggtcctg cagcctcaag acctgctggc tgcagctggc cgagttccgc      900

aaggtcgggg accggctgaa ggagaagtac gacagcgcgg ccgccatgcg cgtcacccgc      960

aagggccggc tggagctggt caacagccgc ttcacccagc ccaccccgga ggacctggtc     1020

tatgtggacc ccagccccga ctactgcctg cgcaacgaga gcacgggctc cctgggcacg     1080

cagggccgcc tctgcaacaa gacctcggag ggcatggatg gctgtgagct catgtgctgc     1140

gggcgtggct acaaccagtt caagagcgtg caggtggagc gctgccactg caagttccac     1200

tggtgctgct tcgtcaggtg taagaagtgc acggagatcg tggaccagta catctgtaaa     1260

tagcccggag ggcctgctcc cggcccccct gcactctgcc tcacaaaggt ctatattata     1320

taaatctata taaatctatt ttatatttgt ataagtaaat gggtgggtgc tatacaatgg     1380

aaagatgaaa atggaaagga agagcttatt taagagacgc tggagatctc tgaggagtgg     1440

actttgctgg ttctctcctc ttggtgggtg ggagacaggg ctttttctct ccctctggcg     1500

aggactctca ggatgtaggg acttggaaat atttactgtc tgtccaccac ggcctggagg     1560

agggaggttg tggttggatg gaggagatga tcttgtctgg aagtctagag tctttgttgg     1620

ttagaggact gcctgtgatc ctggccacta ggccaagagg ccctatgaag gtggcgggaa     1680

ctcagcttca acctcgatgt cttcagggtc ttgtccagaa tgtagatggg ttccgtaaga     1740

ggcctggtgc tctcttactc tttcatccac gtgcacttgt gcggcatctg cagtttacag     1800

gaacggctcc ttccctaaaa tgagaagtcc aaggtcatct ctggcccagt gaccacagag     1860

agatctgcac ctcccggact tcaggcctgc ctttccagcg agaattcttc atcctccacg     1920

gttcactagc tcctacctga agaggaaagg gggccatttg acctgacatg tcaggaaagc     1980

cctaaactga atgtttgcgc ctgggctgca gaagccaggg tgcatgacca ggctgcgtgg     2040

acgttatact gtcttccccc acccccgggg aggggaagct tgagctgctg ctgtcactcc     2100

tccaccgagg gaggcctcac aaaccacagg acgctgcaac gggtcaggct ggcgggcccg     2160

gcgtgctcat catctctgcc ccaggtgtac ggtttctctc tgacattaaa tgcccttcat     2220

ggaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                                    2251


<210>  746
<211>  5238
<212>  DNA
<213>  homo sapiens

<400>  746
acacacacac acacactcac aggctcattg gcagacaggg ccacaactcg cggctctagg       60

gaaggccaca gacctcagct gtacgagcgg aacctggact agaggaactt tcctcaggac      120

tcagggcaca cagcccctcg gccactactg tctgcgagcc cgaggcgcag gggagcgcca      180

gcggctgcag gtacgctgcg cacccgcact ggggcctggg cggtgcagcg gcggcgggag      240

ggtcctggga accgcagccg ccgaggccag tgtgtgagcc ggccggccgc ggcaagccgc      300

atcccccggc cgcccctcgc agccccttgc tccccggcag ccgccgccgc cctcaggcag      360

cccagccggg cgctcgcgcc aggacttccc cgccgcccgc ctcggcccgg aacatggctg      420

cgcgccctgc tgccaccctc gcctggtcgc tactgctcct ctcctcagcc ctgctccgcg      480

aaggctgccg agcgcgcttc gtcgccgagc gggactcgga ggacgacgga gaggagccgg      540

tggttttccc ggagtcgccc ctgcagagcc ccacggtgct cgtggcggtc ctcgcccgca      600

acgcggcgca cacgctgccg cacttcctcg gctgcctgga gcggctggac taccccaaga      660

gcaggatggc catctgggca gccactgatc acaatgtgga taatacaaca gaaatattca      720

gggagtggtt gaaaaatgta cagagactct atcactatgt ggagtggagg cctatggatg      780

aaccagagtc ttaccctgat gaaattggac caaagcactg gccaacctcc cggtttgccc      840

atgtgatgaa actacgacag gcagcccttc gaactgcgag ggaaaaatgg tcagactaca      900

ttctgttcat agatgttgac aatttcctga ctaatccaca gaccctcaat ctactgattg      960

cagaaaacaa aactattgtg gcccccatgc tggagtctcg gggcctgtat tctaatttct     1020

ggtgcggaat cacccctaag ggcttctata agaggacccc agactacgtt cagattcgag     1080

aatggaagag gacaggctgc ttccccgtcc ccatggtcca ctccaccttc ctaattgacc     1140

tcaggaagga ggcctcggac aagctgactt tctacccccc acaccaggac tacacctgga     1200

cctttgatga catcattgtc tttgccttct ccagcaggca agcaggcatc cagatgtacc     1260

tctgcaacag agagcactat ggctacctgc ccatccccct gaagccccat cagacactgc     1320

aggaagacat cgagaacctc atccatgtgc agattgaagc aatgattgac cgtcctccaa     1380

tggaaccctc ccagtatgtc tcagttgtcc ctaaatatcc agacaagatg ggatttgatg     1440

agattttcat gataaacctc aaacgcagaa aggacaggcg ggaccggatg ctgcgcacac     1500

tgtatgaaca ggagattgag gtcaagattg tcgaggctgt ggatggaaag gcactcaaca     1560

caagccagct gaaggcactg aatattgaaa tgctgcctgg ctatcgagat ccctattcct     1620

ccaggcctct aacaaggggt gaaatcggct gctttctcag ccactactca gtctggaaag     1680

aggtaattga tcgagagcta gagaagactc ttgtaattga agacgatgtg cgttttgagc     1740

atcagtttaa gaagaagctg atgaagctga tggataacat tgaccaggct cagctggact     1800

gggaactgat ttatattggt aggaagagga tgcaagtaaa ggagccagag aaagcagtgc     1860

ccaatgtggc aaacctggtc gaagccgact attcctactg gaccctgggc tacgtcatct     1920

ctctggaagg agcacagaag ctggttggag ccaatccttt tgggaagatg ctgccagtgg     1980

atgagtttct gccagtcatg tacaacaagc atcccgtagc cgagtacaag gagtattatg     2040

aatccaggga cctgaaagcc ttctctgcag aacccttgct catctaccct acgcactaca     2100

caggccagcc ggggtacctg agtgacacgg agacctccac catctgggac aatgagacag     2160

tggccaccga ctgggatagg acacatgcct ggaagtcccg gaagcaaagc cgcatctaca     2220

gcaatgccaa gaacacagag gccctgccac cgccaacctc cctggacact gtgccttcaa     2280

gggatgagct atgaaggctc cctgggagtg tggcccacat cagttcaaca tcctctggtt     2340

tttctaaagg gctattcatc tgtttgctcc agttttctgt tttgttttgt tcttagtggt     2400

cacagtcatc taaccaaagt gatctagtgt gatagatcga aattaacata tttttgacca     2460

tggaaggaaa taaggaaatt caacccaaat ttcccaagac ggctgaaaga caggtttttt     2520

ggaaactgtt aagataaact gtaatccaga cacctaattc ttcagttcac tactcatgtg     2580

atactgattc ccacattaag gttgaacaac atggctcaga gtcttgttca agagaaagtg     2640

atcaccgagc tgtcacatca gcaaatatgt agtcaaggca gccaggccaa ctagaccaca     2700

cttattggtc tagtttgtcc gttttatatg acattgaaaa cttgtgtgtg caacttttgg     2760

gggacaggaa tcacttaaaa tcatatttat ttggcttttt atttaaagga ttctgtcaca     2820

agtcttattg aaaagtagat tttttaaaaa aaaaaaatct tagtccctgt tatccagtag     2880

gggtgggtat ttgggtccga ctgagacttg gcctgtgacc atcatggcag ttggagttct     2940

catatagagg tgaccagttt gccatgtgga tataatttag tagatatttg acagtttgtg     3000

taggtatttg agggaaaaaa ctcaatgttt ggctttttta ttatggccac tcgagtcagg     3060

atgctctatt tataaagata aatgtaatat ataaagggtg aggactggct gtgcatcctg     3120

ccctgtcccg ggtttgcgcg ctgctacaga gcttcacgct ctccgctcca ccccttagcc     3180

tgggaaccca ccgcaggtgt gagttctgtg agtcactgct aagagacaga gcacattttc     3240

aggccagcaa ctatccttgc cagagttttt tcattatatt ttgaattatt tattttacaa     3300

aatgggcgaa gatattgtct ttaggataag gcagagaaac agatgttgca gacttccacg     3360

gcacccgggg gagtggtggg tgtggacaca ttggttcggc aatctgattc tcctgaattt     3420

cccagccagg ctcttgtggg gaggcctgtg gatgggggga tttgaactat ttggaaacaa     3480

atgattctct atctcaggtg agaaacctgg tcagaaacaa agggctggtc acctgattta     3540

ggccagcaac cagggaagct cttagaatcc caggcggaca ccctttctca aaagatatcc     3600

cctaagagtc ctttctgctt tcttcacaga ttgattttat gtaaaatgca gagttggact     3660

acacgatttc ttcccactcc acaatctgtc atcctagtat agatcatggt ggtttccctc     3720

aagtttatgt tctcatgccc tcaatctgta aatttttgtc tccagaaaaa ccctcccagg     3780

catcccatac cagcaccgtt cctcatcact gtccatgcac catgcagcca tatggggggc     3840

cgtgcacacc ccaaaccctg agcttcacac ttaaactcat ggggagggcc cttcagagca     3900

gagtccacag gcgggtggtg ctacatacac aagcttagtg tacgagtgta agatacactt     3960

taagccagac acctaattct tcagttcact gcccatgtga tactgattgc cacattaagg     4020

ttgaacagca tggctcagag tctagagaaa gtgatcacca agctgtctca tcaccaaata     4080

ggtagtcaag gcagcctcat ctccccaggt gaggggcggg tccccacttt aggacaagag     4140

gcagcttgcc ttccaccaga cgccagcctc ggccttcctt cccgactcac tgtgggtacc     4200

cttctacact gaccagcaag ctaggccgct ggaggaaagg gaactcaccc aactctaaat     4260

tgtgccgctt agacttagct gtcagtgtga cttcctttcc cacccacccc cagaaaaaca     4320

gaaagagcat ctggggagcg agtgaaaatt ccttaggtga ttcctaagat ttccttgggt     4380

atctggtttt tgttttcata tttgagtgtg tgcatgtgtg catgacttta atgacttttt     4440

taatggggtg ggaggtggct ggggtgctgg ggttgaagga agtttgggtt gatttttgtg     4500

gtgttttgtt taatagagaa tttttttttt cctgttcccc tgtcagctgg tctgacagat     4560

ttaagaactc tcattcttaa aagactttgg acttaaattc tagcatttta gactaggact     4620

gttctactgt gaagaaagtt ctgtctcctt tagcccggtt tgtttctccc tgctcaggtc     4680

tagaatccca agcagtgttc ttttctggtg aacactgtga gccgcagatg tgactttttt     4740

tttaaagtca tctcttcagc aatccagagg ttccttgacc tcattatttg tcctatctct     4800

cccttatagt cctaagccaa gacatttgac ctttgacatt tgacctttgc agtgtcatgt     4860

gagggcgtca gtatagaggc ctttgcatct gggcctggca cccgctctct gcctctggag     4920

gctaaaccct gtctggattt ctcttgggat ctaacgtggg atcttctgga cagacaaccg     4980

tgacatcagc agtgctggtg ctgctgtgtg tggactgaac acctgcactt tgcagaggac     5040

acgctgcatg ggccccgctt gcggttcatt caggcctgct gcaggagctc tgagaacaag     5100

aaagagtgga cacccgttcc cctgcatcat ctgtcttgcg tgctatttca gagtggggaa     5160

gtgataaact atttgccttc tggagctctt tgtgaaaaat taaaaaaaaa cttagctcaa     5220

agaaaaaaaa aaaaaaaa                                                   5238


<210>  747
<211>  5014
<212>  DNA
<213>  homo sapiens

<400>  747
acgtgaccta ggctgcggcg gcggcgtgct gcgggctctg tggcgggagc gaggccgacg       60

ggcggggccg cgcggccgcg tgacgcgaag cgttcgagag cgcgcgtcgt ggaacgtctt      120

ggttgccacg gcaagcgcgc gcgcgaggcc ttgggaacct cgggaccggc ccccggcgag      180

cgcagcggcg cccagtagtc atcttagtgg gatttgggga agcaacaggg ctgtgtgggg      240

taacctgcca cctttaagtg gaaatcagaa atggagcaag agccacaaaa tggagaacct      300

gctgaaatta agatcatcag agaagcatat aagaaggcct ttttatttgt taacaaaggt      360

ctgaatacag atgaattagg tcagaaggaa gaagcaaaga actactataa gcaaggaata      420

ggacacctgc tcagagggat cagcatttca tcaaaagagt ctgaacacac aggtcctggg      480

tgggaatctg ctagacagat gcaacagaaa atgaaagaaa ctctacagaa tgtacgcacc      540

aggctggaaa ttctagagaa gggtcttgcc acttctctgc agaatgatct tcaggaggtg      600

cccaagttat atccagaatt tccacctaaa gacatgtgtg aaaaattacc agagcctcag      660

tcttttagtt cagctcctca gcatgctgaa gtaaatggaa acacctcaac tccaagtgca      720

ggggcagttg ctgcacctgc ttctctgtct ttaccatcac aaagttgtcc agcagaagct      780

cctcctgctt atactcctca agctgctgaa ggtcactaca ctgtatccta tggaacagat      840

tctggggagt tttcatcagt tggagaggag ttttatagga atcattctca gccaccgcct      900

cttgagacct tagggctgga tgcagatgaa ttgattttga taccaaatgg agtacagatt      960

ttttttgtaa atcctgcagg ggaggttagt gcaccttcgt atcctgggta ccttcgaatt     1020

gtgaggtttt tggataattc tctcgatacg gttctaaacc gtcctcccgg gtttcttcag     1080

gtttgtgact ggttatatcc tctagttcct gatagatctc cggttctgaa atgtactgcg     1140

ggagcctaca tgtttcctga tacaatgcta caagcagcag gatgctttgt gggggtcgtc     1200

ctgtcctctg agttaccaga ggatgataga gagctctttg aggatctgtt aaggcaaatg     1260

tctgaccttc ggctccaggc caactggaac agagcagaag aagaaaatga attccaaatc     1320

cctggaagaa ctagaccctc ctctgaccaa ctaaaagaag cctctggcac tgatgtgaaa     1380

cagttggacc aaggcaataa ggatgtacgt cataaaggaa aacgtggaaa aagggctaaa     1440

gatacttcaa gtgaagaagt taacctgagt cacattgtac catgtgagcc agttccagaa     1500

gaaaagccaa aagaattacc tgaatggagt gaaaaagtgg ctcacaacat tttgtcaggt     1560

gcttcctggg tgagttgggg tttagtcaaa ggtgctgaga ttactggtaa ggcaatccag     1620

aaaggtgctt ctaaactccg agagcggatt caaccagaag aaaaacccgt ggaagttagt     1680

ccagctgtca ccaagggact ttatatagcg aagcaagcta caggaggagc agcaaaagtc     1740

agtcagttcc tggttgatgg agtttgcact gtagcaaatt gcgttggaaa agaactagct     1800

ccacatgtca agaagcatgg aagcaaactt gttccagaat ctcttaaaaa agacaaagat     1860

gggaaatctc ctctggatgg tgctatggtt gtagcagcaa gtagtgttca aggattttca     1920

actgtctggc aaggattgga atgtgcagct aaatgcatcg ttaacaatgt ttcagcagaa     1980

actgtacaaa ctgtcagata caaatacgga tataatgcag gagaagctac ccaccatgcg     2040

gtggattctg cggtcaatgt tggcgtaact gcctacaata ttaacaacat tggtatcaaa     2100

gcaatggtga agaaaactgc aacacaaaca ggacacactc tccttgagga ctatcagata     2160

gttgataatt ctcagaggga aaatcaagaa ggagcagcaa atgtcaacgt gagaggggag     2220

aaggatgagc agacgaagga agtaaaggag gcaaagaaga aagataaatg atgaagtgct     2280

gggaatcact tataccaaag ccttatgaaa tggatgaaat tttgttaaat aggcaaatgt     2340

ggaattcctc acagattaac cagtattttt taaatgtatt cattcctaca aattaacttt     2400

cataaatttt atggcatgtc ttctatttaa aaggaaaaga ataagtattc ttgcatctgg     2460

ccttagaaat gtgaagttat attctcaagt ttattttttt ccaagtgtag ctaaaatatt     2520

tttgcaggta aaataaagct gatagtacat gtgttgttca aaccttgtta aacctaatat     2580

tgaactattt ttatatctgc tgtctttcag aaggcaaata ggaaactata tatttgctta     2640

aaaattggca tttagtaacc ttaattcttt ttatagaagg aatgacttaa agtattgtcc     2700

cctctttttg cactaattgt ggattttttt agatgcttct caaaattttc agtgtgtaag     2760

ctaaacaaaa actaaaacta agaattctca aaaaaacttg ttcaaaacag ggaaagactg     2820

atgaaaagta aaatggacta cttttgtaac ttacctgttt gttaggaaat ggaatggtct     2880

ctttgattta aaataaataa aaatagatta ttacgtcttt tgtattgaga ctgtattgtt     2940

atgagcctag gaaatttggg aacatgattg tattgtatta aaattcgaag tgattattat     3000

cagcttaatt ggattaaaaa agtacttcaa gaaattattt tatcatatct gcttctgttt     3060

ttccaaaagg ttaaaacttg taaaaaaaat atatataaac aattgagttt actaatggta     3120

aacattttta ttctgggatt cggtcattgg aatttatatt aaaagacaag ttattaaaaa     3180

ggaaaggttc tattcataat cagggtaaag aatatgaaaa ccttagacgt aatccatggt     3240

ggataggcat tatggtttcc actttggcag aaggcagact attcacagcc ctatttactt     3300

acataggcta aaaaactatg taactaaata cctaatggta tttaattttt gtttattgaa     3360

tttaagagat tggtattagt tttcatagct gtagtccatt ctaataattt ctgatcttct     3420

agtggctact taattagaca ttatttgaag ctgtctgaag aatgcacttt atgaattaaa     3480

aaactgaatt gcctgacctc gttatcacat gagcttatat tttgggaaca catagaactg     3540

atggaggctt ttcctaaggc caaggataat gtactagttg ttaaaatgga aataaaagtg     3600

aagtggtaaa tagcttacag acagtctatg ctttgtttaa gaaatggaat ggcacttcat     3660

atattctcat ttgtgggagc taaaaattac aataatcaaa cttaaggaga tagagagtag     3720

aatgatggtt accagaggct gggaggcatt gaagggatgg ggagggaagt gaggttgatt     3780

aatgggtacg aaaatatagt tagaacgaat ttgttgtagt atttgatagc ccaacagggt     3840

gactacagtc aacaataact ttatacattt aaaaataaaa gagtgtaatt gggacgtttg     3900

taacacaaat gaatgcttga agcagtagat acaccctgat gtaattatta taaatcgcat     3960

acctgtatca aaatatctca tgtatcccat aaatatatac acctaccatg tacccataaa     4020

aatttaaaaa gaaatggaat ggcaaataat ggaacataaa ctttaaacag ttagctttga     4080

ccagaggtca gcaaatatcc tccatgggct aaatccagat gtccacctgt tttcataaat     4140

aacgttttat tggagcatag ctgtacccat ttgtttacat attggctatg gctgctgtct     4200

agttcaacgt gagagttgaa tagttgcatc agagagtata tggtccacaa gcctaactta     4260

ttcactctct ggccctttgc agaaaaagtg tgctgcctta gtctatagaa aatggacttt     4320

tcccaccatt cactgactca ttaggagata ggcatcttct aaagattttt tttatattgt     4380

gtaatgattg atatatagat aaaattatat attacttgta aggtatgatg aataacaaca     4440

cttaaaaact catcacacct aaagacatgg aaagctgcca attacctata tgtatgttct     4500

tcctattttc ttacctcttt ccccatgtca ttttttattg ttccttgcca ttttttaatc     4560

acacatgtat gttctccaaa catactgttt cattttttga agctttctac atatagtgtc     4620

tgaatgtgaa gtcttactca acttgctttt ttgagtttat gtttaaaatt cattcttgcg     4680

cttatatgca tggatggttt acttgctcta tagtattctg tgtgagtata ccacaattta     4740

agtgttcatt ttcctatcag ttgacatttg tttttagttt ttgttggtag aaacagtaca     4800

ctcaaaacat ccttgactgt cccctggtac acatatgcaa gagactttat gcgtaagagt     4860

ggagttgttg gcttgtcaag ttttgcaaaa taatgccagg tattttccaa aatgatgata     4920

ttctcttgag tattacttcc ctttgcaatg tttttattgt taatgtagca tatataaaaa     4980

agtatctcat aattttaaaa aaaaaaaaaa aaaa                                 5014


<210>  748
<211>  4007
<212>  DNA
<213>  homo sapiens

<400>  748
acttccgctc cacgcagcgc ctgtgctgcc gcgtctcgac gtgtcaccgg cggcgccgct       60

gctgtggcaa aggaaggagc tgactggggg agttcgaggc ggcgggcggc ggtgaccccg      120

gcctggaact gccccggtac ggaagtgttc cggggtccgt ggggagcagg agagggaggc      180

ggcggaccgt cccgcgcggg gcacgatgtt gaacatgtgg aaggtgcgcg agctggtgga      240

caaagccacc aatgttgtta tgaattattc agagatcgag tctaaggttc gagaggcaac      300

gaacgatgat ccttggggac cttctgggca actcatggga gagattgcca aggctacatt      360

tatgtatgaa caatttccag aacttatgaa catgctttgg tcacgaatgt taaaagacaa      420

caaaaagaat tggagaagag tttataagtc gttgctgctc ctagcttacc tcataaggaa      480

tggatcagag cgtgttgtta caagtgccag agaacacatt tatgatttac gatccctgga      540

aaattaccac tttgtagatg agcatggtaa ggatcaaggt ataaatattc gacagaaggt      600

gaaggaattg gttgaatttg cccaggatga cgacaggctt cgtgaagagc gaaagaaagc      660

aaagaagaac aaagacaagt atgttggggt ttcctcagac agtgttggag gattcagata      720

cagtgaaaga tatgatcctg agcccaaatc aaaatgggat gaggagtggg ataaaaacaa      780

gagtgctttt ccattcagtg ataaattagg tgagctgagt gataaaattg gaagcacaat      840

tgatgacacc atcagcaagt tccggaggaa agatagagaa gactctccag aaagatgcag      900

cgacagcgat gaggaaaaga aagcgagaag aggcagatct cccaaaggtg aattcaaaga      960

tgaagaggag actgtgacga caaagcatat tcatatcaca caggccacag agaccaccac     1020

aaccagacac aagcgcacag caaatccttc caaaaccatt gatcttggag cagcagcaca     1080

ttacacaggg gacaaagcaa gtccagatca gaatgcttca acccacacac ctcagtcttc     1140

agttaagact tcagtgccta gcagcaagtc atctggtgac cttgttgatc tgtttgatgg     1200

caccagccag tcaacaggag gatcagctga tttattcgga ggatttgctg actttggctc     1260

agctgctgca tcaggcagtt tcccttccca agtaacagca acaagtggga atggagactt     1320

tggtgactgg agtgccttca accaagcccc atcaggccct gttgcttcca gtggcgagtt     1380

ctttggcagt gcctcacagc cagcggtaga acttgttagt ggctcacaat cagctctagg     1440

cccacctcct gctgcctcaa attcttcaga cctgtttgat cttatgggct cgtcccaggc     1500

aaccatgaca tcttcccaga gtatgaattt ctctatgatg agcactaaca ctgtgggact     1560

tggtttgcct atgtcaagat cacagaatac agatatggtc cagaaatcag tcagcaaaac     1620

cttgccctct acttggtctg accccagtgt aaacatcagc ctagacaact tactacctgg     1680

tatgcagcct tccaaacccc agcagccatc actgaataca atgattcagc aacagaatat     1740

gcagcagcct atgaatgtga tgactcaaag ttttggagct gtgaacctca gttctccatc     1800

gaacatgctt cctgtccggc cccaaactaa tgctttgata gggggaccca tgcctatgag     1860

catgcccaat gtgatgactg gcaccatggg aatggcccct cttggaaata ctccgatgat     1920

gaaccagagc atgatgggca tgaacatgaa catagggatg tccgctgctg ggatgggctt     1980

gacaggcaca atgggaatgg gcatgcccaa catagccatg acttctggaa ctgtgcaacc     2040

caagcaagat gcctttgcaa atttcgccaa ttttagcaaa taagagattg taaaagaagc     2100

agattgaatg aagaattttt agctgtgcag ataggtgatg ttgggatgga aaatgctaat     2160

caactaccct ttcttttatc aagtaattaa aataaatcta cataaagaac caaaaaggct     2220

gttttataaa agtgaaatat ccagtatttc agagggccag gcaagagcac ttcagatgag     2280

gcagtcaaaa tcattttttt ccagtgagga tagaccacaa gtgggtggtg agaccattga     2340

aagcctttat caactgaaga gtccatttaa cagcataatt tgtgggaaga ctggaatagg     2400

gctgaataaa tgtgtttgaa tctctaattt tatactttct tttcctgagg aacttgattt     2460

ttctgtccct ggatcgcctt gtcataattg ggtctgttcc ttttactacc actcttgagt     2520

ccatatatga aatcattaaa gttggatgat cagtttttta taaaaatata tatttttgtc     2580

caagaaaaaa aaaagcatac atatgtgatt atggctaaat caaaggtaac tggaatgtat     2640

atacttttgc taatgttcca gcaacactgc tattatacta tccaaatttt tattgtaaca     2700

aaacctcttt aagcaattgg tgattgccat gggacttttc ccatgtcttc tgctgtaatt     2760

atcctgtgca gaactaggaa gaaatttttt tcaggactgc tctatggttt cctttaaaag     2820

aaaaaaactt ctgtttgttt ttagcagtca ttatttacaa tttgcagtga ttaacttggc     2880

aaggcttcct tccgtgttta tccctgtagc catcatttaa gtcaggaaca gtcagaaaaa     2940

tatttatttt attttttttt tgggtgtctg caaaggtaaa aatccattaa aaccttaagt     3000

taaatataaa tgttacaact caatgtttgc ttttagattt tatacagtat ttgttttgtt     3060

ttggttttga gtgtatataa tgcagcatta gcaatatggt tccaatagag gagttaaata     3120

tatattgtta aaggagacct gtagcagtca aagattttat tgatttaatg acaaaggaaa     3180

ttaatgaaaa tgtttttgtt tttctgctgt aattctgcat taagctcaca tgaaaatcat     3240

gattctagag tttggaatgc aaaattaatt gttttaccct caagctggga atatttttca     3300

aaataaatac tataatatag atatcaaatt attacctccc catgttatgt tgaaaatttt     3360

tttattaaat tgataaaact ttatttccat tatattcata atgttctgtt atacataaca     3420

ttaaaatgtt cattaaaatc aatgttgaac tgctttttct ttcgttctgt tagacatttg     3480

agaccatttg gggaaaaaat aattatagtt tgggcaaagt aatttttata aataatttaa     3540

aattatttaa tgacttctct attctttcct atcagactct actgttagga attaaaaatg     3600

aagcagcaaa gatatcctga cctgctccat tcttgctaat gttccatcta caacatttct     3660

aattaggcag aaattcatgt acttcagcta agtggtaatg aaaagtgatt catttgctga     3720

ataagagatg agagtgagtg taattagctg actgcggttt ttaatctttc aacaattcaa     3780

tgtgtttaac ttagtttcaa agaataggag ctttcaagtg ttgttacttc agagcaatca     3840

agccagcctc tggtggccgc atagtagaat atggtccctg atatttaaaa ccgatcatct     3900

taagtaaatt ttttctttaa gaagtatatc ttcactttct caaatatgta tggttcttag     3960

acgaagtaaa tgtttatctg aaccttaaaa aaaaaaaaaa aaaaaaa                   4007


<210>  749
<211>  1085
<212>  DNA
<213>  homo sapiens

<400>  749
cgtgtgtatg tgtatttggg gggactgaag ggtacgtggg gcgaaacaaa accggccatg       60

gcagcagcgg aggaggagga cgggggcccc gaggggccaa atcgcgagcg gggcggggcg      120

ggcgcgacct tcgaatgtaa tatatgtttg gagactgctc gggaagctgt ggtcagtgtg      180

tgtggccacc tgtactgttg gccatgtctt catcagtggc tggcacggcc agaacggcaa      240

gagtgtccag tatgtaaagc tgggatcagc agagagaagg ttgtcccgct ttatgggcga      300

gggagccaga agccccagga tcccagattg aaaactccac cccgccccca gggccagaga      360

ccagctccag agagcagagg gggattccag ccatttggtg ataccggggg cttccacttc      420

tcatttggtg ttggtgcttt tccctttggc tttttcacca tcgtcttcaa tgcccatgag      480

cctttccgcc ggggtacagg tgtggatctg ggacagggtc acccggcctc cagctgacag      540

gattccctct tcctgtttct cgccatcttc ttcttttttt ggctgctcag tatttgagct      600

atgtctgctt cccgcccacc tccagccaga ggagaatcag tattgagggt ccctgctgac      660

ccttccgtac tcctggaccc ccttgacccc tctatttctg ttggctaagg ccagccttgg      720

acattctcca ggaaggcctg gggaggagga gtgaagtctg tgcatagatg ggagagcctt      780

ctgctcagag gctcactcag taacgttgtt taattctctg ccctggggaa ggaggatgga      840

ttgagagaat gtctttctcc tctcctaagt ctttgctttc cctgatttct tgatttgatc      900

ttgaaaggtg ggcaaagttc cctctgactc ttcccccact ccccatctta ttgatttaat      960

ttaatttttc actccccaga gtctaatatg gattctgact cttaagtgct tcctccccct     1020

cactacctcc tttaatacaa attcaataaa aaaggtgaaa taaaaaaaaa atcaataaag     1080

caaaa                                                                 1085


<210>  750
<211>  2063
<212>  DNA
<213>  homo sapiens

<400>  750
gctgggagtc ctggtgccgc cggctgcact tctgtgtgtc tttcaggaag ccacagggca       60

gggggcgtct gtgcagagaa gcgggggagt gagtagcagg caggcccagc ttgtgtacca      120

gcccagtgac atatatagaa acataaatca ggctagagcc ggcgcgcccg ggcgcgcacc      180

tgtgtatgga cccgcaggca tgtctgtaca ctgggtgggc acctgtcttg tgagtggctc      240

cgggtgtggc tgctcctcgg actttcagtt tatgtaagat ttatctctag gggcctacct      300

tcccccatct ccagagggga acataagaag tttaacggag ctgggactga gcagattaag      360

ggagtggagc ggaggctggg ccggagagag tggggactgt gagtgctagt gggtaaggat      420

ccatctgttt gccccgtccc ccagccagaa aggcattttg gaaagactgg cgtggcaagc      480

gtcgccctga aacgtccaca gagcccaaga agtgatgatc actgagtgag tggcactggg      540

ctgagactgg ccagtttgtt aacaacaggg atgctagcag ttaggaaggc caggaggaaa      600

ctcaggatgg ggaccatctg ctcccccaac cccagcggga caaagacatc atcggaggtc      660

tgcaatgccg actggatggc ctcgctcccc cctcacctcc acaacctccc cctttccaat      720

ctggcaatcc caggctcaca tgattcattc agctactggg tggatgaaaa gtccccagtg      780

gggcctgacc aaacccaagc tatcaaacgc ctcgccagga tctccttggt gaagaagcta      840

atgaagaagt ggtctgtgac tcagaacctg acatttcgag aacagctgga agctgggatc      900

cgctactttg acctgcgtgt gtcttccaaa ccaggggatg ccgaccagga gatctacttc      960

atccatgggc tttttggcat caaggtctgg gatgggctga tggaaattga ctcgtttctt     1020

acacagcacc cccaggagat tatcttcctg gatttcaacc acttctatgc catggatgag     1080

acccatcaca aatgcctggt tctgcggatc caggaggcct ttggaaacaa gctgtgccca     1140

gcctgcagtg tggaaagttt gacgctgcga actctgtggg agaagaactg ccaggttctt     1200

attttctacc actgtccctt ctacaagcag taccccttcc tgtggccagg aaagaagatt     1260

ccagcgccct gggcaaacac cacaagtgtg cgcaaactaa tcctcttctt ggagaccact     1320

ctgagtgagc gggcctcacg gggctccttc catgtctccc aagcgatcct cacccccaga     1380

gtgaagacca ttgcccgggg cttggttggg ggcctcaaga acacgctggt tcataggctg     1440

gcactgatcc cagtttatcc tttgagattc agcagaagat cctgatggag gaggaggata     1500

ccaagagaga ggtgcccaag gaagatggag ttggtgatgt gcaacatttc ggtgagaact     1560

ttattgtcag aggttttcag tacatattta caagttctta ctccatcata catattggga     1620

atgagctggc attttcaagc atatacccag gagtccagca atcattgggg aagagagcct     1680

gaggctggca atccttgccc agaactttgg tcacctgctt gttcacaggc caccatatct     1740

tacttcactg aagtcatatg ctgaggtttt atttagtcca gatgctgaag gatgggaaga     1800

cccaagcagc tggtgtggag gtctttccca gtgactcatc agtcattcag aaatcaaagc     1860

ctgcacaaga aagggtggga tgggatgtat agagaaagac accaagcctt tagactccag     1920

cagagtagct gatattgaca tatctgagga gggaggaggc tccaatacga ctactcccaa     1980

ttcacagggt ttgtggttct ggatgaaatc tttgcaaagg gtttccctgg cactcaaaca     2040

gaataaatag gcttataaag tgt                                             2063


<210>  751
<211>  2280
<212>  DNA
<213>  homo sapiens

<400>  751
agactaagct gcaacactgg cagagcctcc caaggaaggg aggagggagg acagaggcca       60

aggcggctcc tggccaccct cgcagcttcc tccctccctg gccacaagga cccaaagctc      120

agagggatgg atgaacagac aggaaggctc aggctggaca cgtattgtat gagtgccaag      180

cagatctggg catggagcaa atgctcagga aggctgtggg atgagcacat gaaatggatg      240

gaaggatgga cggacagatg gacagatgga tggatggatg gatggatgga tgagtggagc      300

ccaacaccag ctctcaggtc ctacggaggt ggcctctctc agcagacgtt catcttcact      360

gacggggaag atgaggccct ggccaggcac acgggcaacg tggtcatcac aaactgctcg      420

gccgcccaca gccgccaggc gctgtcctgc aagatggccg tggagtatga ccgcttcatc      480

gagtccggca ggaagtggtt ctgccacgtg gacgatgaca actacgtcaa cctgcgggcc      540

ctgctgcggc tgctggccag ctacccgcac acgcgggacg tctacgtcgg caagcccagc      600

ctggacaggc ccatccaggc catggagcgg gtcagcgaga acaaggtgcg tcctgtccac      660

ttctggtttg ccacgggcgg cgctggcttc tgcatcagcc gtgggctggc tctgaagatg      720

agcccgtggg ccagcggggg tcacttcatg aatacggctg agcggatccg gctgcctgat      780

gactgcacca tcggctacat cgtggaggcc ctgctgggtg tgcccctcat ccgcagcggc      840

ctcttccact cccacctgga gaacctgcag caggtgccca cctcggagct ccacgagcag      900

gtgacgctga gctacggtat gtttgaaaac aagcggaacg ccgtccacgt gaaggggccc      960

ttctcggtgg aggccgaccc atccaggttc cgctccatcc actgccacct gtacccggac     1020

acaccctggt gtccccgcac tgccatcttc tagtggccat ggctgagacc caatccctgg     1080

gcgcccctgg tatccaaagg gcccagggac cctgttgcgc tgccctggcc tcggcattcg     1140

aggctcccct agggccgtgc ctgtgcgtgt gcgtgtgcgt gtgtgtgtgt gtgtactgca     1200

tgcccacccg ggtagcaggc tgctgggcag ttctgctctg tggaggggcg ggcaccagcg     1260

ccacttatgt gcctctgctc cgagggccag tgggctgcag ggcctgcttg gaggaaggat     1320

ttgtgtgtcg gaggccactc cgagggcaat tctgttagga tttttggatc tttctacagc     1380

tacggggctc cgggctactt tgcagggatg cgatgcgtag gtgcctttct cttcctgctg     1440

accacaagct ctgtgctggg ggtacctgtg ccctgaagtc ctggcccctg tgtcatagcc     1500

ccaagtacga ctcactgagc catgctcatt gcaggggagg ctgggtctgg gggtgcgtga     1560

cccaatcccc ttcctcctgg cctggacgct gtggcttaag agtaacagca gccaccgccc     1620

agttccagtg gccccacgaa gcccccagtg gctggctgtc cagctgggca aacagtggca     1680

cccctcccag ctcttctgag tggggagtct tccaggcctc ctcagaggtc ttccctttgc     1740

ctccccagga cagggtgagt cagagctcag catttaatct cctctccaaa gtagagagca     1800

agtcgcccac agtgggcgtg tctgtaaata ttgtgacagt atttttttac tgtgctgttt     1860

tttttgaaag gggatgggta aaaagtaggg tgttcttgtt ttttgcttgg gagggtgggg     1920

gtgggggagg gtcttatttt atcttatctt ttctgtggat cagaaaaaac agaagccaaa     1980

ctcggggtca tctttgtttt taaagctgaa gtgggactgt ctggcactct gtgtatttat     2040

gcgttccagc atctggaacc tcccatccct gccctcctcc tgtgtagctg ccacctcccc     2100

gctgggccca gcatggctca cctgtcccgt gggctgtgtt tcttgttgtt tttctctttg     2160

caaagacata gctaggaaag cgaatgataa gggaaaagtt ctcagggaat tgaagtgttg     2220

ttgctatggt gacgtccttt tgctgtgaat aaaggtgctc tttgcagcaa aaaaaaaaaa     2280


<210>  752
<211>  2932
<212>  DNA
<213>  homo sapiens

<400>  752
ggggagccct aggctcggcg ctgccggagg ggcccgagcc gagccgcctg cgccccggcc       60

gggcagcgcc gggcccgctt cccgcggggc cacgccctgt caaactttgt tgcggcggct      120

agcgcagcgg gcccgcaagc gggcgggagg ggcgccgggc cgggccgggc agggcgcggg      180

cggctagggg ctccgagagc ggcggccccg gcccgcggcc ccaccatgcc ccagctcggc      240

ggcgggggcg gcggcggcgg cggcggcagc gggggaggcg gcggctccag cgccggggcg      300

gccggcggag gggacgacct cggggcgaac gacgagctga tccccttcca ggacgagggg      360

ggcgaggagc aggagccgag cagcgatagc gcctcggcgc agcgggacct agacgaggtc      420

aagtcgtccc tggtcaacga gtcggagaac cagagcagca gctcggactc ggaggcggag      480

aggcgcccgc agcccgtccg ggacactttc cagaagccgc gggactattt cgccgaagtg      540

agaaggcctc aggacagcgc gttctttaaa ggacccccgt accctgggta ccccttcctg      600

atgatcccgg acctgagcag cccgtacctc tccaacggac ccctgtctcc cggaggagcg      660

cgcacctacc tgcagatgaa atggcccctc ctcgatgtcc cctccagcgc cacagtcaag      720

gacacgaggt caccatctcc agcacacttg tctaataaag ttcctgtcgt tcagcacccg      780

catcacatgc atccgctgac tcccctcatc acctacagca atgaccactt ctcccccggc      840

tcccctccca cccacctctc cccagagatc gatccaaaga caggaatccc ccggccccct      900

cacccatccg agctgtcacc gtattaccca ctctctcccg gagctgtcgg acaaatcccc      960

caccccctcg gctggctcgt cccacagcaa ggccagccca tgtactccct tcctcccggt     1020

ggcttccggc acccttaccc cgccctcgcc atgaacgcct cgatgtccag cctggtctcc     1080

agtcggttct ctcctcacat ggtggctcct gcccaccctg gcctgcccac ctcagggatc     1140

ccccaccctg ccatcgtctc ccccatcgtc aagcaggaac cggcaccccc cagcctgagc     1200

cctgcagtga gcgtgaaatc accagtcacc gtgaaaaagg aggaggaaaa gaagccccac     1260

gtgaagaagc ctctgaatgc cttcatgttg tatatgaagg agatgagggc caaggtggtg     1320

gctgagtgca ccctgaagga aagtgcagcc attaaccaga tccttggaag aaagtggcac     1380

aacctgtctc gagaagaaca ggccaagtac tacgagctgg cccggaagga gcggcagctt     1440

cactcgcagc tctacccaac ctggtcagcc cgggacaact atggtaagaa aaagaagagg     1500

aagagagaaa agcagctgtc ccagacacag tcacagcagc aagtccagga ggcagagggt     1560

gccctggcct ccaagagcaa gaagccatgt gttcagtacc tgccccccga gaagccctgt     1620

gacagccctg cctcctccca cgggagcatg ctggactccc cggccactcc ctctgcagct     1680

ttggcctcac cagctgcccc tgctgccacc cattcggagc aagcccagcc cctctccctc     1740

accaccaaac cagaaacccg ggcccagctg gctctccact ctgccgcctt cctgtcggct     1800

aaggctgcag cctcctcctc tgggcagatg ggcagccagc ctcccctcct gtcccggccc     1860

ctcccccttg ggtccatgcc cacagctctg ctggcctctc ccccgtcctt ccccgccacg     1920

ctccatgccc accaggccct cccggtgcta caggcccagc ctctttccct ggtcaccaag     1980

tctgcccact aagctccccc cgacccctgc aggctgtcac atgactcatt gagtagtaat     2040

gattcagaag aaaaagaaaa aggagacttt attggtcaat atttgaccac tctggactgt     2100

tctgtaaagt ggctggtaac aacagcactt tacagtttgt agatgtaacc agtagctgat     2160

cttaaggctt ttttaaaaaa caaaacaaaa caacaaaaaa aaatctttat aagaaagaga     2220

actgaaaagt agcgtgctat tcgtcctgta ggtgctgtgg tggatggacc tgggcagagg     2280

gcacttctct ctcttacctc tcttgcactt tctgtctcct gtctcttctc gcccctgccg     2340

cctgccccag cttccccgac tccatctgca gctctgccat tgtgacattt cctgttaccc     2400

agcccaagtt ttcatcgtct gctcaatacc gtgggttctt cttcgtcctc tgtcctctgc     2460

ccagtgtgag gccatcacca tgtgagaaga catcttggcc tgatttgctg ccaccagcgt     2520

cccctccctc agtgggcccg aactcgccag ccccagcttt cagtggagaa agcggtcctc     2580

tgaaatggtt tcctcccaac ccccgcattt aaagggactc aaggtgcctg ccacttcctc     2640

agcgaagaag tctgtgttcc tccccgtcct tgccagtggc gatcatccct tcacaatccc     2700

agagtggcag gcgggaccgg ccccatggtc tggctcctgt cacctgggtc cgtgccagca     2760

caatctgcca aagttctaga gaccctgttc ccttccccat cacctcacat gcttcttctg     2820

tgtgtatttc tttttgtttt tatggttttt ggagcaattt aaactcccag ttgtttattt     2880

tcacaaaaga aaataaaatt gcagttgcaa gaccttttaa aaaaaaaaaa aa             2932


<210>  753
<211>  1804
<212>  DNA
<213>  homo sapiens

<400>  753
gtgcagcccg tgccccccgc gcgccggggc cgaatgcgcg ccgcgtaggg tcccccgggc       60

cgagaggggt gcccggaggg aagagcgcgg tgggggcgcc ccggccccgc tgccctgggg      120

ctatggccat ggtgaccggc ggctggggcg gccccggcgg cgacacgaac ggcgtggaca      180

aggcgggcgg ctacccgcgc gcggccgagg acgactcggc ctcgcccccc ggtgccgcca      240

gcgacgccga gccgggcgac gaggagcggc cggggctgca ggtggactgc gtggtgtgcg      300

gggacaagtc gagcggcaag cattacggtg tcttcacctg cgagggctgc aagagctttt      360

tcaagcgaag catccgccgc aacctcagct acacctgccg gtccaaccgt gactgccaga      420

tcgaccagca ccaccggaac cagtgccagt actgccgtct caagaagtgc ttccgggtgg      480

gcatgaggaa ggaggcggtg cagcgcggcc gcatcccgca ctcgctgcct ggtgccgtgg      540

ccgcctcctc gggcagcccc ccgggctcgg cgctggcggc agtggcgagc ggcggagacc      600

tcttcccggg gcagccggtg tccgaactga tcgcgcagct gctgcgcgct gagccctacc      660

ctgcggcggc cggacgcttc ggcgcagggg gcggcgcggc gggcgcggtg ctgggcatcg      720

acaacgtgtg cgagctggcg gcgcggctgc tcttcagcac cgtggagtgg gcgcgccacg      780

cgcccttctt ccccgagctg ccggtggccg accaggtggc gctgctgcgc ctgagctgga      840

gcgagctctt cgtgctgaac gcggcgcagg cggcgctgcc cctgcacacg gcgccgctac      900

tggccgccgc cggcctccac gccgcgccta tggccgccga gcgcgccgtg gctttcatgg      960

accaggtgcg cgccttccag gagcaggtgg acaagctggg ccgcctgcag gtcgactcgg     1020

ccgagtatgg ctgcctcaag gccatcgcgc tcttcacgcc cgacgcctgt ggcctctcag     1080

acccggccca cgttgagagc ctgcaggaga aggcgcaggt ggccctcacc gagtatgtgc     1140

gggcgcagta cccgtcccag ccccagcgct tcgggcgcct gctgctgcgg ctccccgccc     1200

tgcgcgcggt ccctgcctcc ctcatctccc agctgttctt catgcgcctg gtggggaaga     1260

cgcccattga gacactgatc agagacatgc tgctgtcggg gagtaccttc aactggccct     1320

acggctcggg ccagtgacca tgacggggcc acgtgtgctg tggccaggcc tgcagacaga     1380

cctcaaggga cagggaatgc tgaggcctcg aggggcctcc cggggcccag gactctggct     1440

tctctcctca gacttctatt ttttaaagac tgtgaaatgt ttgtcttttc tgttttttaa     1500

atgatcatga aaccaaaaag agactgatca tccaggcctc agcctcatcc tccccaggac     1560

ccctgtccag gatggagggt ccaatcctag gacagccttg ttcctcagca cccctagcat     1620

gaacttgtgg gatggtgggg ttggcttccc tggcatgatg gacaaaggcc tggcgtcggc     1680

cagaggggct gctccagtgg gcaggggtag ctagcgtgtg ccaggcagat cctctggaca     1740

cgtaacctat gtcagacact acatgatgac tcaaggccaa taataaagac atttcctacc     1800

tgca                                                                  1804


<210>  754
<211>  1804
<212>  DNA
<213>  homo sapiens

<400>  754
gtgcagcccg tgccccccgc gcgccggggc cgaatgcgcg ccgcgtaggg tcccccgggc       60

cgagaggggt gcccggaggg aagagcgcgg tgggggcgcc ccggccccgc tgccctgggg      120

ctatggccat ggtgaccggc ggctggggcg gccccggcgg cgacacgaac ggcgtggaca      180

aggcgggcgg ctacccgcgc gcggccgagg acgactcggc ctcgcccccc ggtgccgcca      240

gcgacgccga gccgggcgac gaggagcggc cggggctgca ggtggactgc gtggtgtgcg      300

gggacaagtc gagcggcaag cattacggtg tcttcacctg cgagggctgc aagagctttt      360

tcaagcgaag catccgccgc aacctcagct acacctgccg gtccaaccgt gactgccaga      420

tcgaccagca ccaccggaac cagtgccagt actgccgtct caagaagtgc ttccgggtgg      480

gcatgaggaa ggaggcggtg cagcgcggcc gcatcccgca ctcgctgcct ggtgccgtgg      540

ccgcctcctc gggcagcccc ccgggctcgg cgctggcggc agtggcgagc ggcggagacc      600

tcttcccggg gcagccggtg tccgaactga tcgcgcagct gctgcgcgct gagccctacc      660

ctgcggcggc cggacgcttc ggcgcagggg gcggcgcggc gggcgcggtg ctgggcatcg      720

acaacgtgtg cgagctggcg gcgcggctgc tcttcagcac cgtggagtgg gcgcgccacg      780

cgcccttctt ccccgagctg ccggtggccg accaggtggc gctgctgcgc ctgagctgga      840

gcgagctctt cgtgctgaac gcggcgcagg cggcgctgcc cctgcacacg gcgccgctac      900

tggccgccgc cggcctccac gccgcgccta tggccgccga gcgcgccgtg gctttcatgg      960

accaggtgcg cgccttccag gagcaggtgg acaagctggg ccgcctgcag gtcgactcgg     1020

ccgagtatgg ctgcctcaag gccatcgcgc tcttcacgcc cgacgcctgt ggcctctcag     1080

acccggccca cgttgagagc ctgcaggaga aggcgcaggt ggccctcacc gagtatgtgc     1140

gggcgcagta cccgtcccag ccccagcgct tcgggcgcct gctgctgcgg ctccccgccc     1200

tgcgcgcggt ccctgcctcc ctcatctccc agctgttctt catgcgcctg gtggggaaga     1260

cgcccattga gacactgatc agagacatgc tgctgtcggg gagtaccttc aactggccct     1320

acggctcggg ccagtgacca tgacggggcc acgtgtgctg tggccaggcc tgcagacaga     1380

cctcaaggga cagggaatgc tgaggcctcg aggggcctcc cggggcccag gactctggct     1440

tctctcctca gacttctatt ttttaaagac tgtgaaatgt ttgtcttttc tgttttttaa     1500

atgatcatga aaccaaaaag agactgatca tccaggcctc agcctcatcc tccccaggac     1560

ccctgtccag gatggagggt ccaatcctag gacagccttg ttcctcagca cccctagcat     1620

gaacttgtgg gatggtgggg ttggcttccc tggcatgatg gacaaaggcc tggcgtcggc     1680

cagaggggct gctccagtgg gcaggggtag ctagcgtgtg ccaggcagat cctctggaca     1740

cgtaacctat gtcagacact acatgatgac tcaaggccaa taataaagac atttcctacc     1800

tgca                                                                  1804


<210>  755
<211>  1020
<212>  DNA
<213>  homo sapiens

<400>  755
actggtgacg tagatctcat gtgaccagga gtcgacgtgt gcagaagtcc tggtaatctg       60

gtccttgttc ccgtctggat accagcttcc ttcagcagcg caggcggtgg tccctgaggc      120

ccgtggaagg agtcaaactt gcgggaattt tgcagtcatt gtattcaaag aagaataagc      180

aagaaagaaa agaaggaagg aagagaggta gacagataca agatgaaatc ctgtcaaaaa      240

atggaaggaa aaccagaaaa tgagagtgaa ccaaagcatg aggaagagcc aaagcctgag      300

gaaaagccag aagaggagga gaagctagag gaggaggcca aagcaaaagg aacttttaga      360

gaaaggctga ttcaatctct ccaggagttt aaagaagata tacacaacag gcatttaagc      420

aatgaagata tgtttagaga agtggatgaa atagatgaga taaggagagt cagaaacaaa      480

cttatagtga tgcgttggaa ggttaatcga aaccatcctt acccctattt aatgtagttt      540

accttgattt ttatctgata ttaacaatac catatagctt gctttttatt agcatttcct      600

gatattcctt tgtccatatt tctacttata acctgttgct attaatggtt ttagatgtat      660

ctcttgttat ctgcatctca ttgtttattg tattttgaac caatctacaa gtctctgtct      720

tttaataaaa gaactttaca catttgtaaa aaagaggttc ttggtaagat ataaaatgga      780

aaaaggctaa gtaatatgtg aatatcatat ttttgaaagg taaaaagtac atttgtatat      840

tacatatatg gacataactt gtgaaggatg aaagaaagta cagcctctcg gtggtgggat      900

tatgaatgat ttttctcctt ttgcttgttt gtattttcta tattcctaaa attaacacac      960

attattattg ctagaataat aaaagtttta taaaaaagaa gcaacaaaaa aaaaaaaaaa     1020


<210>  756
<211>  1102
<212>  DNA
<213>  homo sapiens

<400>  756
actggtgacg tagatctcat gtgaccagga gtcgacgtgt gcagaagtcc tggtaatctg       60

gtccttgttc ccgtctggat accagcttcc ttcagcagcg caggcggtgg tccctgaggc      120

ccgtggaagg agtcaaactt gcgggaattt tgcagtttat ctgcagggct gttgtttcca      180

gcaagaccca aagctagaaa aggaggagga agaaactgac ccgatcagtg ccagaagtca      240

ttgtattcaa agaagaataa gcaagaaaga aaagaaggaa ggaagagagg tagacagata      300

caagatgaaa tcctgtcaaa aaatggaagg aaaaccagaa aatgagagtg aaccaaagca      360

tgaggaagag ccaaagcctg aggaaaagcc agaagaggag gagaagctag aggaggaggc      420

caaagcaaaa ggaactttta gagaaaggct gattcaatct ctccaggagt ttaaagaaga      480

tatacacaac aggcatttaa gcaatgaaga tatgtttaga gaagtggatg aaatagatga      540

gataaggaga gtcagaaaca aacttatagt gatgcgttgg aaggttaatc gaaaccatcc      600

ttacccctat ttaatgtagt ttaccttgat ttttatctga tattaacaat accatatagc      660

ttgcttttta ttagcatttc ctgatattcc tttgtccata tttctactta taacctgttg      720

ctattaatgg ttttagatgt atctcttgtt atctgcatct cattgtttat tgtattttga      780

accaatctac aagtctctgt cttttaataa aagaacttta cacatttgta aaaaagaggt      840

tcttggtaag atataaaatg gaaaaaggct aagtaatatg tgaatatcat atttttgaaa      900

ggtaaaaagt acatttgtat attacatata tggacataac ttgtgaagga tgaaagaaag      960

tacagcctct cggtggtggg attatgaatg atttttctcc ttttgcttgt ttgtattttc     1020

tatattccta aaattaacac acattattat tgctagaata ataaaagttt tataaaaaag     1080

aagcaacaaa aaaaaaaaaa aa                                              1102


<210>  757
<211>  6550
<212>  DNA
<213>  homo sapiens

<400>  757
aataaagaac gaggacactg cggggtgtgc ggcggcccaa gcggtttcaa acggcttaga       60

gcaggccgct tggttctgac ccagctgagg aaatactctt aattctaagg aaaacctgga      120

agcacaatgg gagatgacag tgagtggttg aaactgccag ttgatcagaa atgtgaacac      180

aagctgtgga aagcaaggtt aagtgggtat gaagaggccc tgaagatctt ccagaaaata      240

aaggatgaaa agagcccaga gtggtccaaa tttttaggat tgatcaaaaa atttgtcact      300

gattccaatg cagtggttca attgaaagga ttagaagctg cacttgttta tgttgaaaat      360

gcccatgtag caggaaaaac cacaggagaa gttgtgtcag gtgttgtaag taaggtgttc      420

aatcaaccta aagctaaagc caaggagctg ggcatagaga tctgtcttat gtacatagag      480

attgagaaag gagaggctgt tcaagaagag ctcctgaaag gcttggacaa taagaatccc      540

aagatcatag tggcctgtat agagacactg aggaaagcct taagtgaatt tggttccaaa      600

atcatcttgc ttaagccaat tatcaaagtg ttgccaaaac tctttgagtc tcgagagaag      660

gctgttcgag atgaagccaa actaattgct gtggagattt acagatggat tcgggatgct      720

ctgagacccc cattacaaaa tataaactct gttcagttga aagaactaga agaagaatgg      780

gtcaaactgc caacaagtgc tcctagacct actcgatttc ttcgttccca acaagaacta      840

gaagctaaat tggaacaaca acagtctgct ggtggagatg ctgaaggagg tggtgatgat      900

ggtgatgagg tgccacaaat agatgcttat gagcttttag aagctgtaga aatcctttcc      960

aaacttccca aagactttta tgacaaaatt gaggcaaaaa aatggcaaga gagaaaagag     1020

gccctggagt ctgtagaagt actaataaaa aaccccaaac tggaagctgg cgattatgca     1080

gatttagtaa aagcattaaa gaaggttgtt ggaaaggaca ccaatgtcat gttggtggct     1140

ttggcagcaa aatgtcttac tggcctggct gttgggctaa ggaagaaatt tggacaatat     1200

gcaggacatg ttgtgccaac catcttggag aaattcaaag agaagaaacc tcaagtggta     1260

caagccctgc aggaggcaat tgatgcaatc ttccttacta ccacactaca gaacatcagt     1320

gaggatgttt tagcagtaat ggataataaa aatccaacca tcaagcagca gacatctctt     1380

tttattgcaa gaagtttccg ccactgcact gcttctaccc tgccaaagag cttgctaaag     1440

cccttttgtg ctgcactact taagcacatc aatgattctg ctcctgaagt cagagatgcc     1500

gcatttgaag cattgggtac tgctttgaag gtggttggcg agaaagcagt aaacccattc     1560

ctagctgatg tggacaaact caagcttgat aagatcaaag aatgttcaga aaaggtagaa     1620

ctgatacatg gtaagaaagc tggactagct gctgataaga aggaattcaa acctctgcct     1680

ggaaggactg ctgcttcagg ggctgcagga gataaggaca caaaggacat ttctgcaccc     1740

aaaccaggac ctctaaaaaa ggcacctgct gctaaggctg gtgggccacc aaaaaagggg     1800

aaaccagctg caccaggagg cgcagggaat actggaacca agaacaagaa aggactggag     1860

actaaagaaa tagtggagcc tgagctctcg atagaagtat gtgaagaaaa agcttcagct     1920

gttcttcccc ctacctgtat acagcttctt gacagcagta actggaaaga aaggctggct     1980

tgtatggaag agttccagaa ggctgttgag ctaatggacc gaactgaaat gccatgccag     2040

gcattagtga ggatgctagc caagaaacct ggatggaaag aaactaattt tcaggtgatg     2100

caaatgaagc ttcatatagt tgctttgatt gcccagaagg gaaatttttc caaaacgtca     2160

gctcaggttg tattagatgg ccttgtggac aagattggag atgtgaaatg tgggaacaat     2220

gcaaaagaag ctatgacagc aatagccgaa gcctgtatgt taccatggac tgctgaacag     2280

gttgtgtcaa tggctttctc acaaaagaat cccaaaaatc agtcagaaac tctgaattgg     2340

ctatcaaatg ccataaaaga atttggtttt tctgggttga atgtcaaagc tttcattagc     2400

aatgtgaaga cagctcttgc tgcaacaaac ccagctgtga ggactgctgc cataaccctg     2460

cttggcgtga tgtatctgta tgttggtccc tctttgcgaa tgttctttga ggatgagaag     2520

cctgccctcc tatcccagat agatgcagaa tttgagaaga tgcagggaca aagtccacct     2580

gctccaacca gaggaatttc caagcatagc acaagtggta cagatgaagg agaagatgga     2640

gatgaaccag atgacgggag caatgatgtc gttgatcttt tgccgaggac ggagatcagt     2700

gataaaatca cttcagagtt ggtatctaag attggtgata agaattggaa gattaggaaa     2760

gaaggcctag atgaagtggc aggtattatt aatgacgcaa aatttatcca accgaatata     2820

ggtgaacttc caactgcctt gaagggtcga ctcaatgatt caaataaaat cttggtacag     2880

caaacgctga atatcctgca acaactggca gtagccatgg gcccaaatat taagcaacat     2940

gtaaaaaatt taggcatccc tatcatcaca gtccttggag acagcaagaa caatgttcga     3000

gctgctgccc tagcgactgt gaatgcttgg gcagaacaga ctggcatgaa ggaatggctg     3060

gaaggagaag atctttctga agagctcaaa aaggaaaatc ctttcttgag gcaagagctt     3120

ctgggctggc tggctgagaa actacctact cttcgttcca cccctacaga ccttatcctt     3180

tgtgttcctc atctctactc ctgcctagaa gatcgaaatg gagatgtgcg aaagaaggcc     3240

caagatgcct tgccattctt catgatgcat ttaggatatg aaaaaatggc caaggctact     3300

gggaaactaa agccaacttc taaagatcag gtattggcca tgctagagaa agccaaagtt     3360

aacatgccag ccaagcctgc tccacccact aaagcaactt ctaaaccaat gggagggtcc     3420

gctccagcca aattccagcc tgcatcagca cctgctgaag attgtatttc cagcagtaca     3480

gaacccaaac ctgatccaaa aaaggccaaa gctccaggat tatcctctaa agcaaagagt     3540

gcacaaggga agaagatgcc aagcaaaacc agcttaaagg aggatgaaga caaatccggg     3600

cctattttta ttgttgttcc aaatggaaaa gagcaaagga tgaaagatga aaaaggattg     3660

aaggtgctaa agtggaattt tactacccca cgggatgaat acattgagca actaaagact     3720

caaatgtcta gctgtgtggc taaatggtta caagatgaga tgtttcactc agactttcag     3780

catcataaca aagcccttgc tgttatggtt gatcacttgg agagtgaaaa agaaggagtt     3840

attggttgcc tggatcttat cttaaagtgg cttaccctga ggttttttga caccaataca     3900

agcgtcctga tgaaagcact agaatattta aaattgctct tcaccttgct aagtgaagaa     3960

gaatatcatc ttactgagaa tgaagcatct tccttcatcc cctatcttgt cgtcaaggtt     4020

ggagaaccaa aggatgtcat tcgtaaagat gttcgtgcca tcctgaaccg gatgtgcctt     4080

gtctacccag ctagcaagat gtttcccttt atcatggaag gaaccaaatc caaaaactct     4140

aagcagagag cagagtgcct ggaagagctg ggatgtctgg ttgagtccta tggcatgaat     4200

gtttgccaac caaccccagg aaaagcctta aaggaaatag ctgttcacat aggagaccgt     4260

gacaatgctg tacgcaatgc tgcactcaac accattgtaa cggtgtacaa tgtacatggg     4320

gatcaggtgt tcaaactgat tggaaatctt tctgaaaagg atatgagcat gctcgaggag     4380

aggattaagc ggtcagcaaa gagaccctct gctgcaccaa taaaacaggt ggaagagaaa     4440

cctcagcgtg cacagaacat aagctccaat gccaacatgt tacgcaaggg accagctgag     4500

gacatgtctt ccaaactcaa ccaagcccga agcatgagtg ggcatcctga ggcagcccag     4560

atggtccgcc gagaattcca gctggatcta gatgagattg agaatgacaa tggtacagtc     4620

cgatgtgaaa tgccagaact tgttcagcac aaactggatg acatttttga gccagtcctt     4680

attcctgaac ccaagatccg ggctgtttct ccacacttcg atgacatgca cagtaataca     4740

gcatccacaa tcaatttcat tatctcccaa gtagccagtg gtgacatcaa cacaagtatc     4800

caagctctga cacagctgtt tcagatagag agccttgccc gggaggcctc cactggagta     4860

ctaaaagacc taatgcatgg cctcatcacc ttaatgctgg attctcggat tgaagatctt     4920

gaggaaggac aacaggtcat ccgctctgtg aacctcttgg tggtgaaggt tctggagaag     4980

tcagaccaga ccaacatcct gagtgcccta cttgttttgc tccaagacag cctgctagca     5040

acagccagtt ctcccaaatt ctcagagctt gttatgaagt gtctctggag aatggttcga     5100

ctgttgcctg ataccatcaa tagcattaac ctagacagaa ttcttctgga tatccacatt     5160

ttcatgaagg tcttccccaa agagaaactg aagcaatgca aaagtgaatt tcccataagg     5220

accctaaaga ccctgctaca caccttatgc aaattaaaag ggcccaagat cctggaccac     5280

ctaacgatga tcgacaacaa aaacgagtct gagctggagg cccatctctg ccggatgatg     5340

aagcacagta tggaccagac tgggagcaag tctgataagg aaacagaaaa gggagcatct     5400

cgaatagatg aaaaatcatc aaaggccaaa gtgaatgatt tcttagctga gatttttaag     5460

aagattggct ctaaagaaaa cactaaagag ggactagcag agttatatga atataagaag     5520

aaatactcag atgctgacat tgaaccattt ctgaaaaatt cctcacagtt cttccagagc     5580

tatgtcgaaa gaggccttcg ggtgattgag atggagaggg agggcaaagg tcgtatttcc     5640

acttcaacag gcatctcccc tcagatggaa gtcacatgtg tgcccacgcc cacaagcaca     5700

gtgtcctcca taggtaacac aaatggggaa gaagtggggc catctgtcta cttggaaagg     5760

ctaaagatcc tccgacagcg atgtggtctg gacaacacaa agcaagatga ccgacctcct     5820

ttgacctctt tgctctccaa accagcagtt cctactgtcg cctcttccac agacatgctc     5880

cacagcaaac tctctcagct ccgggagtca cgggagcagc accagcattc agacctggat     5940

tctaaccaga ctcactcttc aggaactgtg acctcctcct cctccacagc taacatagac     6000

gacttgaaaa aaagactgga gagaataaag agcagtcgca aatgaagctg ccccactccc     6060

ccggcaccct gcagctttag tttactaaac tagaagtcct catagtttaa aatggcctca     6120

gcaggcctag tgtatacaaa ctggttgtat gtatcatgcc gtggagctag ggggaggagt     6180

cattgtggca caagtatttg tacatactct gcttctctct gtcagcgtcc tgctgctcta     6240

gaagactgtc cgtggatgag tttagtgtac agacttgtaa acagctgccc cctctctgct     6300

cagtctagtt cccagatcct tttcttttct ttttaattgc tcatttgtaa aattgtccta     6360

atctttccta gctttttaat agttaatatt agaaactctt taatagtttt cctttcagtt     6420

tgtgagctct tctctgtcgc cctgaagggt cactgtattc tgtatgaatg catggcatga     6480

tacaactaat ttaagagtct tttataaata aagtttgcat taactatacc tgacaaaaaa     6540

aaaaaaaaaa                                                            6550


<210>  758
<211>  3284
<212>  DNA
<213>  homo sapiens

<400>  758
gtctccctcc gggcaccacg ggggccgccg tcctggcacc aacttgaggg gctgtgcggc       60

ggagggcggc tgcggagcgc ccgcgcgggc tgcacctgct cagggagctg cccctctgtt      120

gttgttgtta ttttccttct tggcgtgcca tcgaggcttt tgggggaaaa aaagaccctt      180

catgtggcct ttataaatat gcgtttgaga cagagttata tgcagaagtt gaaaatgcct      240

ggaagatttc tggtttcttt cactacttat cctgcctttt tgcatcgctg ccagatttgg      300

atgatatgat attcagaggg gcaccttaat caaagccatt cttcaacaag acccacctgg      360

cataagattg cacacataat tcaagatggc cagtcaacct cctgaagaca ctgcggagtc      420

tcaggcctct gatgagctgg agtgcaaaat ctgttacaat cgatacaatc tgaaacagag      480

gaaacccaaa gtgctggagt gttgtcatag ggtttgtgcc aaatgcctct acaagatcat      540

agactttggg gactccccac aaggtgtcat tgtctgtcct ttctgcaggt ttgagacgtg      600

cctgccagat gatgaagtta gtagcctgcc cgatgacaac aacatccttg taaacttgac      660

ttgtggaggc aaagggaaga agtgcctgcc agagaaccct actgagctgc tgctcacccc      720

caagaggctg gcctctctgg tcagtccttc tcacacgtcc tccaactgcc tggtcataac      780

catcatggag gtgcagagag agagctcccc gtccctgagc tccactcctg tggtagaatt      840

ttataggcct gcgagtttcg actctgtcac cactgtgtca cacaactgga ctgtgtggaa      900

ctgcacgtcc ctgctgtttc agacatccat ccgggtgtta gtgtggttgc taggtttgct      960

ctacttcagc tccttaccct taggaatcta cttactggtg tctaagaaag tcacccttgg     1020

ggtcgtcttt gtcagcctgg tcccttcgag cctcgttatt cttatggtgt atggtttttg     1080

ccagtgtgtt tgtcatgaat ttctagactg tatggcacct ccttcttaac tgatatgcaa     1140

aataagaaat tggacacaca ttgccctgtt tgagtgtgaa gttagataat ttataattta     1200

ttttctttta tgttctttat gattagtatc catgacatta acaaaaccct tggccacatg     1260

ttgacttgat tggttttcct gtaggctgga agtaaaaatg ttcatttcta cttaggggtt     1320

agcaaaattg tataagctca cacttcatgg agcactgaca gcagtgagtc ttcccagaga     1380

aaggacaggg tttctctcag cactgccaga cagacggcag gggtgtggtg tgttatacta     1440

tagggagagc atggatccct cctttcgtat tcatggatgt tctatgatgg cagttggaca     1500

caagaggaaa gttgctctga gacacaaagt gtgtactcct ttcccacccc atacccctgg     1560

tattggaaca ccctagaatt gtcttcaggt gttttctctc ttaagtcact ctctgtggtc     1620

ggcgatccca ttgagatact tgtttcctct gcccattctc ccttgccaag aggaaactcg     1680

gttccattcc cttgggtagt ttcaactgaa taccagtttt gccacattac taaggagaat     1740

gaaaagcact gaggaatttg catcacagtc agcttcatgg cagaatgtgg ccatttgtcc     1800

ttgagacaca ctctttcctc catgtctgtt ttcctctctc ctcagtctta tctgagaaga     1860

atggaggaga aggaacttct catacagcgg ttattattga tgaaaacctt catttgagtc     1920

tttccttata acatcttagt tttggttttt ttaaaccaca ttgcccaatc agcctcaccc     1980

cttgtcctga aaaggttcca tttaaattag ttgctataaa ttcatcaata ctttttttcc     2040

ctattatatt tttggttcta ttaggattta cttaactgaa tcttataaca attcgaggtg     2100

aactgtggca atgaaaacca gaaacagtta atgagatgct tcagctcaca gtttgaagtg     2160

ctgagaacct aagtattttg ctgtacggta ctgagctgta ccaaaatatg atggtttagg     2220

tttatgtgca agactttgtg ttgtagtcta gacaaagggg tgggcaagag acatgcaaag     2280

ctgaagccct gcttgaaaag acccttcaag gaagtaaaat ggcaggggca gagtgcagct     2340

taacatgttg ctatccctgt tgtttttgag ttggttttgg aatggattca agttcttaca     2400

caatttattt tgaatacaag cataatctag gtgatttgag ttaatgaact tcttttcatg     2460

atgtagggaa agttgaatgt atatatttct aagaagaatt tgtttagcag attacaagtt     2520

ggcaaaatag actgttcaca gaaactaggc aaaaatttaa aaaaacattc tagtctctaa     2580

aacccattac taatgattaa cattaaaata tttgtaactc ttagaaaggg ggcattacta     2640

agacgacttt aacttgttat gaaatctttg ttgtgtgatg caggtacagt gcgcccattc     2700

caactggaat agcagtttga ttttaattgt aaaactaaac ttcgggaata tgtatgccca     2760

aagtaagtag gatgagaata gtatacatgg gatatggtcc aatgaattta agccccaaga     2820

tacagctaaa tacatttatg atttcataaa atctagttta gatagcattg tgatgcaatt     2880

tccagaaatc catttgtgtt tagagtaaat accatgttta gaagatgttt tgtggtttgg     2940

atttatatat ttgtaaggtt tttttaaaaa aatgttcgtt ttgtttgaaa tgtaacattg     3000

agtaaattgg tgagttatat aatgagattt ctagaaagct ctggacatgg gtacgatgtg     3060

ttttgcttct ctgtataatg tctacagtga taaacttgtg tctccgtgta ttgtggcagt     3120

ctttttttct agttaatttg gctttagaga gcaatctttg tatgacacca gaaaactctt     3180

catgctattg aatgataaaa agataatgct ttaatatttt attcactgtg atactatttt     3240

gtttgtctat taaattgtta ttatttccaa atttaaaaaa aaaa                      3284


<210>  759
<211>  1843
<212>  DNA
<213>  homo sapiens

<400>  759
gcggaatggg gcgggacttc cagtaggagg cggcaagttt gaaaagtgat gacggttgac       60

gtttgctgat ttttgacttt gcttgtagct gctccccgaa ctcgccgtct tcctgtcggc      120

ggccggcact gtagattaac aggaaacttc caagatggaa actttgtctt tccccagata      180

taatgtagct gagattgtga ttcatattcg caataagatc ttaacaggag ctgatggtaa      240

aaacctcacc aagaatgatc tttatccaaa tccaaagcct gaagtcttgc acatgatcta      300

catgagagcc ttacaaatag tatatggaat tcgactggaa catttttaca tgatgccagt      360

gaactctgaa gtcatgtatc cacatttaat ggaaggcttc ttaccattca gcaatttagt      420

tactcatctg gactcatttt tgcctatctg ccgggtgaat gactttgaga ctgctgatat      480

tctatgtcca aaagcaaaac ggacaagtcg gtttttaagt ggcattatca actttattca      540

cttcagagaa gcatgccgtg aaacgtatat ggaatttctt tggcaatata aatcctctgc      600

ggacaaaatg caacagttaa acgccgcaca ccaggaggca ttaatgaaac tggagagact      660

tgattctgtt ccagttgaag agcaagaaga gttcaagcag ctttcagatg gaattcagga      720

gctacaacaa tcactaaatc aggattttca tcaaaaaacg atagtgctgc aagagggaaa      780

ttcccaaaag aagtcaaata tttcagagaa aaccaagcgt ttgaatgaac taaaattgtc      840

ggtggtttct ttgaaagaaa tacaagagag tttgaaaaca aaaattgtgg attctccaga      900

gaagttaaag aattataaag aaaaaatgaa agatacggtc cagaagctta aaaatgccag      960

acaagaagtg gtggagaaat atgaaatcta tggagactca gttgactgcc tgccttcatg     1020

tcagttggaa gtgcagttat atcaaaagaa aatacaggac ctttcagata atagggaaaa     1080

attagccagt atcttaaagg agagcctgaa cttggaggac caaattgaga gtgatgagtc     1140

agaactgaag aaattgaaga ctgaagaaaa ttcgttcaaa agactgatga ttgtgaagaa     1200

ggaaaaactt gccacagcac aattcaaaat aaataagaag catgaagatg ttaagcaata     1260

caaacgcaca gtaattgagg attgcaataa agttcaagaa aaaagaggtg ctgtctatga     1320

acgagtaacc acaattaatc aagaaatcca aaaaattaaa cttggaattc aacaactaaa     1380

agatgctgct gaaagggaga aactgaagtc ccaggaaata tttctaaact tgaaaactgc     1440

tttggagaaa taccacgacg gtattgaaaa ggcagcagag gactcctatg ctaagataga     1500

tgagaagaca gctgaactga agaggaagat gttcaaaatg tcaacctgat taacaaaatt     1560

acatgtcttt ttgtaaatgg cttgccatct tttaattttc tatttagaaa gaaaagttga     1620

agcgaatgga agtatcagaa gtaccaaata atgttggctt catcagtttt tatacactct     1680

cataagtagt taataagatg aatttaatgt aggcttttat taatttataa ttaaaataac     1740

ttgtgcagct attcatgtct ctactctgcc ccttgttgta aatagtttga gtaaaacaaa     1800

actagttacc tttgaaatat atatattttt ttctgttact atc                       1843


<210>  760
<211>  1989
<212>  DNA
<213>  homo sapiens

<400>  760
gcggaatggg gcgggacttc cagtaggagg cggcaagttt gaaaagtgat gacggttgac       60

gtttgctgat ttttgacttt gcttgtagct gctccccgaa ctcgccgtct tcctgtcggc      120

ggccggcact gtaggtgagc gcgagaggac ggaggaagga agcctgcaga cagacgcctt      180

ctccatccca aggcgcgggc aggtgccggg acgctgggcc tggcggtgtt ttcgtcgtgc      240

tcagcggtgg gaggaggcgg aagaaaccag agcctgggag attaacagga aacttccaag      300

atggaaactt tgtctttccc cagatataat gtagctgaga ttgtgattca tattcgcaat      360

aagatcttaa caggagctga tggtaaaaac ctcaccaaga atgatcttta tccaaatcca      420

aagcctgaag tcttgcacat gatctacatg agagccttac aaatagtata tggaattcga      480

ctggaacatt tttacatgat gccagtgaac tctgaagtca tgtatccaca tttaatggaa      540

ggcttcttac cattcagcaa tttagttact catctggact catttttgcc tatctgccgg      600

gtgaatgact ttgagactgc tgatattcta tgtccaaaag caaaacggac aagtcggttt      660

ttaagtggca ttatcaactt tattcacttc agagaagcat gccgtgaaac gtatatggaa      720

tttctttggc aatataaatc ctctgcggac aaaatgcaac agttaaacgc cgcacaccag      780

gaggcattaa tgaaactgga gagacttgat tctgttccag ttgaagagca agaagagttc      840

aagcagcttt cagatggaat tcaggagcta caacaatcac taaatcagga ttttcatcaa      900

aaaacgatag tgctgcaaga gggaaattcc caaaagaagt caaatatttc agagaaaacc      960

aagcgtttga atgaactaaa attgtcggtg gtttctttga aagaaataca agagagtttg     1020

aaaacaaaaa ttgtggattc tccagagaag ttaaagaatt ataaagaaaa aatgaaagat     1080

acggtccaga agcttaaaaa tgccagacaa gaagtggtgg agaaatatga aatctatgga     1140

gactcagttg actgcctgcc ttcatgtcag ttggaagtgc agttatatca aaagaaaata     1200

caggaccttt cagataatag ggaaaaatta gccagtatct taaaggagag cctgaacttg     1260

gaggaccaaa ttgagagtga tgagtcagaa ctgaagaaat tgaagactga agaaaattcg     1320

ttcaaaagac tgatgattgt gaagaaggaa aaacttgcca cagcacaatt caaaataaat     1380

aagaagcatg aagatgttaa gcaatacaaa cgcacagtaa ttgaggattg caataaagtt     1440

caagaaaaaa gaggtgctgt ctatgaacga gtaaccacaa ttaatcaaga aatccaaaaa     1500

attaaacttg gaattcaaca actaaaagat gctgctgaaa gggagaaact gaagtcccag     1560

gaaatatttc taaacttgaa aactgctttg gagaaatacc acgacggtat tgaaaaggca     1620

gcagaggact cctatgctaa gatagatgag aagacagctg aactgaagag gaagatgttc     1680

aaaatgtcaa cctgattaac aaaattacat gtctttttgt aaatggcttg ccatctttta     1740

attttctatt tagaaagaaa agttgaagcg aatggaagta tcagaagtac caaataatgt     1800

tggcttcatc agtttttata cactctcata agtagttaat aagatgaatt taatgtaggc     1860

ttttattaat ttataattaa aataacttgt gcagctattc atgtctctac tctgcccctt     1920

gttgtaaata gtttgagtaa aacaaaacta gttacctttg aaatatatat atttttttct     1980

gttactatc                                                             1989


<210>  761
<211>  9336
<212>  DNA
<213>  homo sapiens

<400>  761
gcggccgcgg gagctgcggg gagcgcgggg gcggcccgga gcgtgccggg gtccccgcgc       60

ctcgctcgcc ggccgcgctc cgaagatggt ggcggcgccg tgcgcccgga ggctggcccg      120

gcgctcgcac tcggcgctgc tcgcggcgct cacggtgctg ctgctgcaga cgctggtcgt      180

gtggaatttc agcagcctcg actccggggc cggggagcgc cgcgggggcg cagcggtcgg      240

cggcggggag cagccgcccc cggccccggc cccgcgccgg gagcgccggg acctgcccgc      300

cgagccggct gcagcccgag gaggaggagg aggcggcggc ggaggaggag gaggacgggg      360

gccccaggcg cgggcgcggg gaggcggccc cggagaaccg cggggacagc agccggccag      420

ccggggggca ctgcccgccc gggctctgga tccacaccca agtccgctca tcaccctgga      480

gactcaggat ggctactttt ctcatcggcc gaaagagaaa gtgcgaacag acagcaacaa      540

cgagaactct gtccccaaag actttgagaa tgtcgacaac agcaacttcg cacccaggac      600

tcaaaagcag aagcaccagc ctgagttggc gaagaagcca ccgagtagac agaaggagct      660

tttgaaaagg aagctggaac agcaggagaa aggaaaagga catacattcc ctgggaaagg      720

ccccggtgag gtgctgcctc ccggggacag agccgcagcc aacagcagcc acgggaagga      780

tgtgtccaga ccgcctcatg ccaggaaaac tgggggcagc tcccccgaga ccaagtatga      840

ccagccccct aagtgtgaca tctcaggcaa ggaggccatc tctgccctgt cccgtgctaa      900

gtccaagcac tgccgccagg agattgggga gacttactgc cgccacaagt tagggctgct      960

gatgcctgag aaggtgactc ggttctgccc cctcgagggt aaagccaaca agaacgtgca     1020

gtgggacgag gactccgtgg agtacatgcc agccaacccg gtcagaatcg cctttgtcct     1080

ggtggtccac ggccgtgcct ctcggcagtt gcagcgcatg ttcaaggcca tctaccacaa     1140

agaccacttc tactacatcc acgtggacaa gcgctctaat tacctgcatc ggcaagtgct     1200

ccaggtctcc aggcagtaca gcaatgtccg cgtcaccccc tggagaatgg ccaccatctg     1260

gggaggagcc agcctcctgt ccacctacct gcagagcatg cgggacctcc tggagatgac     1320

cgactggccc tgggacttct tcatcaacct gagtgcggcc gactacccca tcaggacaaa     1380

tgaccagttg gtggcgtttc tctcccgata ccgagatatg aatttcttga agtcacacgg     1440

ccgggacaat gcaaggttca ttcggaagca gggcctggat cggctcttcc tggagtgcga     1500

cgctcacatg tggcgcctgg gagatcggcg gatcccagag ggcattgccg tggatggcgg     1560

ttcggactgg ttcctgctga accggaggtt tgtagaatat gtgaccttct ccacagacga     1620

tctggtgacc aagatgaaac agttctactc ctacaccctg cttcctgctg agtccttctt     1680

ccatacggtc ctggagaaca gcccccactg cgacaccatg gtggacaaca acctgcgcat     1740

caccaactgg aatcgcaagc tgggctgcaa gtgccagtac aagcacatcg tggactggtg     1800

cggctgctcc cccaatgact tcaagccgca ggacttccac cgcttccagc agacagcccg     1860

gcctaccttc tttgcccgca agtttgaagc cgtggtgaat caggaaatca ttgggcagct     1920

ggactattac ctgtacggga actaccctgc aggtaccccg ggcctgcgct cctactggga     1980

gaatgtctac gatgagcctg acggcatcca cagcctgagc gacgtgacac tcaccttgta     2040

ccactccttt gcccgcctgg gtcttcgacg ggccgagacg tccctgcaca cggatgggga     2100

gaacagctgc cgatactacc caatgggcca cccagcatct gtgcacctct acttccttgc     2160

tgaccgcttc cagggctttc tgatcaagca tcatgctacc aatctggctg tgagcaaact     2220

agagactctg gagacctggg tgatgccgaa aaaagtcttc aagatcgcaa gcccacccag     2280

tgactttggg aggcttcagt tttccgaggt cggcactgac tgggatgcca aggagaggct     2340

attccgcaac tttgggggtc ttctggggcc catggatgag ccggtgggta tgcagaagtg     2400

ggggaaggga cctaatgtga ccgtgaccgt catttgggtg gatcccgtca atgtcatcgc     2460

agccacctac gacatcctca ttgagtccac tgccgaattc acacactaca agcccccttt     2520

gaacttgccc ctgaggcctg gggtctggac agtgaaaatt ctccaccact gggtgccagt     2580

tgcagagacc aaattcctcg ttgcgcctct gaccttctcg aacaggcagc ccatcaaacc     2640

tgaggaggca ctgaagctgc acaatgggcc cctccgcaat gcctacatgg agcagagctt     2700

ccagagccta aaccccgtcc tcagcctgcc catcaacccc gcccaggtgg aacaggcacg     2760

gaggaacgca gcctccacgg gcacagcgct ggagggatgg ctggactcgt tggtgggcgg     2820

gatgtggact gccatggaca tctgtgccac gggccccaca gcctgcccgg tcatgcagac     2880

ctgcagccag acggcctgga gctccttcag ccctgacccc aagtcggagc tgggggcagt     2940

caaacctgat ggccggctca ggtagcactg ggcacgagga gtgggccaca gcaggatctc     3000

aacgggaaag cagccagagg ggttgtgggg cctgaacccc ggcctcccac cctgggggag     3060

gccctctgtg aatgggtctc tcctggccat agaatgatgg aaagggaagg tcagcaggtc     3120

aaagcaggat cagccaacaa cctgcctttg gcaagctgcg ggtgggatgg ctcagtccct     3180

gcactgtgac tgtctcacct cttctggttg atcctcaagt cctacaggtt ccttgtcttc     3240

cccttccagt gacccacccc tgaccccaga cgtgtgattt tcagactttt ctttcgagca     3300

gcagaacttc gtttacggag cacagtcata agtggaggtt cagggtgctg acgaaatcca     3360

agctgctctg gttgaagctg acaagtgcga ggttccctcc caaagctcag ccctctgggc     3420

ggtccccttg cccagggtat ctcctacggt acctcttcag aacccaaggg ctctgcaaat     3480

gccagtttga caagcactgc ccagaccaac catgggttca aactccagcc ctgccctttg     3540

gttcattttt ctgcttctct tggctggggg actctggtgc cagccttgaa agtcatggtc     3600

gtgggccctt tcccatggag gctgcagcct taggagagct ctgagcctct cagcagccct     3660

ccttgggttg aactattctc cttagtaact aggtaagtgg gaaagccttt tgatgtggca     3720

tggccaaggt ccagccacaa gtgcaactgc cacctgtcca ggggtctggg cctccttccc     3780

tcaaggctgc cacacaaagt agcagaaata ggatgatgtt tgtgagcacc agactcaaga     3840

ccatgacctt ctttgatcct tgaaaatggg aactttgaca gccatgacca tgaaactcac     3900

aaggcaacgc gatgaaactc acaaagcaat gcttggagca aaactcctga gctagacagc     3960

acagcagcac ccatcccctg ccagagccct tccgttctga ggtcagacac acaaaacctt     4020

cgtcaattgc acaccggtgc tgttgggagt gaccaaacca catgaaccag acttttcccg     4080

tccaggaaat agcatttcag atttggtttt taatttcatg cccttcggcc acaggctcaa     4140

cgggacatgc aacataaaaa tgggaaggtt atttaaacaa caaaaaacag tatgatttaa     4200

gtgttgagtt accagaaacc caaaaggttt ccttgccacg agccccctgg agtgtcatcc     4260

ctgttcacca ggagagctct tcgcaggagg cctcccttgc tcctgtaatc ccacctcccc     4320

tgaatgatgg gattcccttg gaaaaaggtc tcacccctgg tagccatctg cccttcccat     4380

ggagagccag tcctgacact tctctccagc gtgggtttga aggggctgcc cttcgctttg     4440

tgtgacttgt cctaatccta gccagatgtg ttgccccatc ccaagcctcg caaggcaggg     4500

tgtcctgttg gcaatggagg acgtagagaa gggacacttt agatatttat tatttacatg     4560

ttttagtcga tgactaatta gtaggtgctg tttttgcagc ttgtcaatta tgttacctta     4620

ctaactgaag ctgcctttat tcacaaaagg ccccttttcc catcttttcc caccccctgg     4680

tgtctctctc tctctcggtt tctctttctc tgcgtctacc ccccatcctc ctcatcctca     4740

gagtaaagca ggggcatcga acaccacgca aagaaagctc caacccgcat cttccactgg     4800

ctttgagtgg ggtgccttgg ggaccgttgg agccttgttt ttttccttat gcagagtgtc     4860

agcctcactc tccctcggat tccaagagta ttggaattcc tgagcctccc atcctccccc     4920

tactcacccc ccgtcacagg cacaaggagg tgacaggcag aaaacgtgga gggtgagtgg     4980

ggaatgtgct agctgcagag agtttgtggg gaatgtgcta gctgcagaga gtttgggcca     5040

ttcctgcttg ctccgtggtt gccttcccat ggcccatcta attatgggca ttcatgcgac     5100

cttaacagag ggaaacaggc tcctttgaga gagatccatc ttaggaggag ggtcgtcaga     5160

tccaggcagc agagtccggg agatagccat tctcaacagc gattccaggg atctcagggt     5220

acttttctca gaaagcccct atgatctctt ttacagactc tatggtggcc acgcgctggg     5280

tgccacatcc tctttctgcc cccggcctct gcctctggcc agggtttccc tggggctgcc     5340

gaagccactt tgggagcttc cctttcaccc tccttgctgg gccaccagtg ctttgtgttc     5400

gcagcgttat ttgcagtggc tttggggact cagcagtggc aagtccctgt gcataatgtg     5460

aacctgcaga cttcaagatg gggcccctcc tgcacccact aacatgtctg cctttttttg     5520

tttttatcct ggaacaagtg gagaaatggc agagctggct gactctgggg acccttccct     5580

ttttcccatg gcttcatttc ttcctcacca caactaattc ggggagctga gaagtcacac     5640

agggtattcc tctcccttct ctgatgttat taattaatag accagagaat aaggttgcag     5700

atattacatt tgttgtgttt ttgtgttttg tttttttttt taaggaaaat cccaaacaaa     5760

gcccagcatg atttgagaaa agaggatgtt ttcccaggga aaataatttt tttaacctgc     5820

ctgagaatga tttatttatt tgttggaggc cattggtcag acagcctgga gcttgggctg     5880

tggaagattt caaaagcata gggctgtggt ctctggaaac ctattacagc ctgcagctgt     5940

gagctgagcc agtgacgagg tccctggaaa ctcaggaagg ctgacaggtg ggccttgggg     6000

tattggtttg tggagaagga agcattcttt aggctgcggc actccttata gtttcccacc     6060

caccgagtga cattcaggca gaaattgagc tcaggagaca gccagccttc ccacatccca     6120

cttcacttcc cggtccacac gtaaagcagt gtgtctccaa ggaggcagtg agcaattccc     6180

aaggtccccg tgttgtgaga agcgcgctgc tttctccctt tgcaggggaa aaaaaaggct     6240

ttcctggtga gatcatgagt ccttccggct tcatttctca ttgtgggttt aacttctaaa     6300

acgcaaatgg agtttagaga ggatgagcag aaccacagga cctgccccca tctctcactc     6360

actgcaattg cttctactct gggcacaagt agggtgtctg aagaccatgt ttccctctgg     6420

ttctctagtt tgcagataac acagaagaca ctggctagaa ccttaagctt tctgccaaaa     6480

agatgcagag agcagggcag tagctactgg cagtggggtg tgaataaaga gtcctttcac     6540

aaccaagttc actgaggatt tggagcacca gcttcccagc agtatcgagg ggtggagagg     6600

tgtacattca ggtggagggg tacatctagg ggtggagagg tgtacattct agaaacagct     6660

gttaacacac tccactttaa agacagcaag ctagacctgc aggatcaaag ccacacactg     6720

tggtaggggt tacaaatgtt tatggggccc agaatactag catagatgcg tgaaatggtt     6780

ggtgtgaggc aaaagggcat ggtgggggca aggatgggga ctgtggtctt actggcatgc     6840

acgtgaccta cccagaatga gcagctgcta ctcagcccca acctgtcatt gtttgtaaaa     6900

atgtaagcac agtgtagtgg aatcttccaa tttggaaggg aagccggaaa tccagattta     6960

atggaaaaaa tctgattttt caacgtcggg ttgtttgttt gtttgttttt gtttttttta     7020

acagatagtg ggcaaagaaa aattccactg ttccacgtgt acactgccag caacctctgc     7080

tctctggaga ggtggtttaa agtgagatta tgcattgccc tggtagaaga ggaaaaaagc     7140

cagcatcagg tcagggcaaa aataacagcc catgttgaac tcggaatggg gacctcttgc     7200

taagtcattc cactcctcaa gagaccattc cacagagggg ggatggatca ttcagctctc     7260

ctggtcccaa gattgtgctg aagggaagaa ggaatagaat ctggagatct ggactgctgc     7320

cccttagata tgcagaggtc cacatctgcc tggggctaca gcttgtggga ctccatcaaa     7380

ccaggccgaa atggcaaaga cagtctagga ggaggaggag gtagggtgtg aaacagccag     7440

gctctctcca aatcccaagt gttgacacag ccatcttgtc ccatccctgg aagcctcttt     7500

ggaaaccaca tagagctgtg ctggctcacg ggatgtcctg tttgcttctg cctcagttac     7560

cttactttgc ccatgggtct accacaggcg ctacctcatt gtgtctgctg agaagtttac     7620

ctgggagggg ggaacaaagt tgtccaaatc tgcttgagct gaatgtatga tctatgcaaa     7680

ttctctctct cctctctctc ttcctctctg gctctcttag aagttttttt gttttgtttt     7740

gttttgtttt gtgtttacct tgcaaacaag atactgtata ggaccctctt aagatggagg     7800

agggctttct tgcgccacct gtgtctaccc ctcacgttgt ctttggctct ggtcttacca     7860

ggcgtatgca gggagaaagt gacctctctt ccctctccac ttggctggga atattccaac     7920

tgcctctgcc tacagatacc accagaaagc gggttctgca ccttgtcatc cccctcccta     7980

acgtcatcta ctccatccct catgttcctc caacttgctt ctcccatccc tccttcaaaa     8040

acaaaacaaa acaaaacaaa agccttaggt ttctcctttt tgaaatgtgg ccttaacatt     8100

atttttggga agctgaccat ccatcctttc cctcccatct ccaccaacat cagagaagac     8160

agcatcgtga agcttctgtg gcagcctcct aaggaagggg ctgccaatct gtagttggca     8220

gatgctatag gaattgctta caaatgtcgt ctttaagaaa aatgttctta tatttttcct     8280

atgggcaaaa tgaaggcttg ggtgctcatc taaagctcag ccaactcctg aagcactctc     8340

tcagagcata ctgctgctgt aatgggctgg cttaattatc ggcagagtgc ttgaaaaggc     8400

tttgcagacc tcccctgccc ccaagactgg gtgactttat atgtacttca ttcaagggta     8460

aatcaggaga cgttctccat ttatctcttc gtccttcctg cctggaaagt gatagcacta     8520

aatattccca gcagatgggt agtgttctca aaggaatcac cctttcccta ccttcagact     8580

ctattcttta cccttccatt gctccagtgc tgatggaggc caaagacaac cccagggttt     8640

tcataggaaa ttcactggaa ttgtgcgcaa ttgtctttgt agtccttttg cctttttttt     8700

ttttaaatat tatgttgtca atagcatttg tttgggtatt tgttttagag gcctcactct     8760

aagttattac cgtccccttc attgttttca aagacatgtg gtgatatagt ttttaaaaat     8820

aactattttg ttatagatca taatatgcat aaaactgtac agaaatattt tgtaatgtgt     8880

tgattttaaa aaaaatctgt aaataaagtt ttaaaaaaag aattcaaatg gcacacgctg     8940

aaatatgtag atattttgct atttatttaa aggagtattt taagagatat tgaactatct     9000

gaaattgacc agtaatcaaa gttccaatca tctgaatgct tttccttgag gtagaatgtg     9060

agtctcagaa atgactgcat tacctgccct tttttgcacc ttttctgtct ttttattttg     9120

cagaacaaca acaacaacaa aattgtgcct tagctgtatt tttttgtcta ggggagtttg     9180

tttctgtctg acaaagcaac attttttgca gaaaacagtg gatgtattaa atactgtatc     9240

ataccaaaaa cactgcaggt gtatatagat gctttctgtc atactgtgtt ttcagatgca     9300

gaattttaaa attaaaaaaa cactgccttt atggaa                               9336


<210>  762
<211>  8106
<212>  DNA
<213>  homo sapiens

<400>  762
agaaagtagc agaaagtgag gctggcaggc ggcggcaaag gagccggcgc gcggcggcgg       60

caggaagtct gtgcccgaga acagcagaaa taagagccag ggagggaccg cggccgcggc      120

ggcggcggcg agagcgaaag aggaaactgc agaggaggaa gctgcgccgc agcccgagcc      180

gcccggcatc cccgccgcct ctgcgcccgc gccgcgcccc cggcgccccc tccccagcgc      240

gcccccggcc gctcctccgc gccgcgctcg tcggccatgg cccgggagaa cggcgagagc      300

agctcctcct ggaaaaagca agctgaagac atcaagaaga tcttcgagtt caaagagacc      360

ctcggaaccg gggccttttc cgaagtggtt ttagctgaag agaaggcaac tggcaagctc      420

tttgctgtga agtgtatccc taagaaggcg ctgaagggca aggaaagcag catagagaat      480

gagatagccg tcctgagaaa gattaagcat gaaaatattg ttgccctgga agacatttat      540

gaaagcccaa atcacctgta cttggtcatg cagctggtgt ccggtggaga gctgtttgac      600

cggatagtgg agaaggggtt ttatacagag aaggatgcca gcactctgat ccgccaagtc      660

ttggacgccg tgtactatct ccacagaatg ggcatcgtcc acagagacct caagcccgaa      720

aatctcttgt actacagtca agatgaggag tccaaaataa tgatcagtga ctttggattg      780

tcaaaaatgg agggcaaagg agatgtgatg tccactgcct gtggaactcc aggctatgtc      840

gctcctgaag tcctcgccca gaaaccttac agcaaagccg ttgactgctg gtccatcgga      900

gtgattgcct acatcttgct ctgcggctac cctccttttt atgatgaaaa tgactccaag      960

ctctttgagc agatcctcaa ggcggaatat gagtttgact ctccctactg ggatgacatc     1020

tccgactctg caaaagactt cattcggaac ctgatggaga aggacccgaa taaaagatac     1080

acgtgtgagc aggcagctcg gcacccatgg atcgctggtg acacagccct caacaaaaac     1140

atccacgagt ccgtcagcgc ccagatccgg aaaaactttg ccaagagcaa atggagacaa     1200

gcatttaatg ccacggccgt cgtcagacat atgagaaaac tacacctcgg cagcagcctg     1260

gacagttcaa atgcaagtgt ttcgagcagc ctcagtttgg ccagccaaaa agactgtctg     1320

gcaccttcca cgctctgtag tttcatttct tcttcgtcgg gggtctcagg agttggagcc     1380

gagcggagac ccaggcccac cactgtgacg gcagtgcact ctggaagcaa gtgactggcc     1440

ctggaggtgg ggcccggggt cggggctggg gaaggggagc cccagggtcg ccagagccgc     1500

gagccactcc agcgagaccc caccttgcat ggtgcccctt cctgcatagg actggaagac     1560

cgaagttttt ttatggccat attttctact gcaattctga agtgttcatt tctcacaaac     1620

tgtactgact cgaggggcgc tgatttcata ggatctggtg ctgtatatac gaatcttgca     1680

aagctctaac tgaacggacc ttcttattcc tctcccctaa caccatcgtt tccactcttc     1740

tcagtgtagg taaccgtcta tggtgtgttt tttcattaat gacaaaaaaa aaaaggtttc     1800

aactggatta tttaaatatt ggtaaatatt gtgcattagg gtttgttttt ccttttaaga     1860

agtatgtcct ttgtatctct aagttacatg acctatatct tttcctcttt aatagtagtt     1920

ttatgttaac ctttaagaga tttgtttttc ctcaaaggag aatttaaagg tattttttaa     1980

aattctaata agaggatcag ccgggtgcaa tgactcatgc ctgtaatccc agcacgttgg     2040

gaggccaagt cgggcggatc acaaggtcag gagatcaagg ccatcctggc caacatggtg     2100

aaaccccacg tctactaaaa atacaaaaaa ttagccgggc gtggtggcac acacctgtag     2160

tcccggctac tcgggaggct gaggcaggag aattgcttga acccgggaga cggaggttgc     2220

agtgagctga gatcgtgcca ctgcactcca gcctgggtga cagagcaaga ctctgtctca     2280

aaaaaaaaaa aaaaaattct aacaagagga tcatgaatct gtctccaagg ctaagagtgc     2340

ccttcacctc tactccttct gtttctctcc ccttccccag gaggaggggc ccctcagttc     2400

tgcgaggctc tcttctctgc gggggacttt ggtagagaat ctgcacagag cctttgctgg     2460

caacccatcc agcagaaccc acacccacca gagaccctag aggcctcttg ccatcagcaa     2520

ccagaaataa gcctgctccc ccgagacgca gggctcagct tcacaggcca gacttgctgt     2580

gagtgagatg cccacactgc agagatgcag gaccctccct tgcaaaagga accagctgcc     2640

atgttgctga aagtgggccc acacacaacc ctcatttctc acgagagcta acagatgaaa     2700

gctcagctat gcagtgttaa aattcatctc tttctctgtg gtttttaaaa aaatgcattt     2760

ctaatcttac acttcacgtg gcctccaaca caaagttctt tctccacatt tttaccctct     2820

tctcacatga atgttttcca agggaaggaa gggagggaag cagccttggg aaaggatcca     2880

tttctggtgg taaggagagg gggccctgcc aggctaatgg gacttcagcc accacagaga     2940

tgaccaaaga ccacctccgc caggcccagc cagtgcttgc agccctccca ttggtcaggg     3000

gagtctaaaa tcaaagatac atggtggtag ggtcaccaaa cgtcccattt gcccgagact     3060

gaaggatttc tcaggctgtg gacatttaat gccaaaacca ggaatatccg gggcaaagca     3120

ggctgtgttg ttcgcctttg tggagccagg cagtgtgtgg cccagggaaa gctgcgtttc     3180

atggaggctt ccaggaggct gccctgtaaa gccaggcagg tggcttcaag tgccattcct     3240

gcaagtgccc ctgcttcagc tctcaggccc atccaatgcc tcgagcccac gggggtgtcc     3300

cggcaggtct gcgtcatcac gacccagtaa cgctgctggc tgtgtcctca tgccctcttc     3360

ctctggctgg ccagtcatgg gaagtcctgt tggttgagtc atctttgtca cttctacacc     3420

tttgagtatg tacaggctga atgttgagtg atgccccccc accctctcaa taaacacaca     3480

cacacacaca cacacacaca cacacacaca caatgttatt aggcacagca gctccatcct     3540

gctccctgag aatggcagtg caggcacaga gaagagcagt tgggaagaca ggcagctggt     3600

ctaccctgtc cccgcacact tcacaggcac tccactgctt ggcaggaatt ctgcatggca     3660

tctgccacgc atgctcacag ggtgaaaaat caagctgtca ctctgcaaaa tctaaaaacc     3720

ctggaaaggt ctataagatg acattagacc cagttaagaa gcaagtgtca cctgagttgg     3780

ccatgcaatg aatgaatatt ataagcagta ttggagaact aggcggttgc ttactaagaa     3840

gtgtcttgga aacattcgag ttcatacagt gcatgacaaa gtaatagaag gctgcaagcg     3900

ctgaaaatgc acccgaatct ggtacctagg atgagtacat gaatagtgat gaatagccct     3960

ttgtgctgtg tgctatatac aaccatttgc attcagaaag cagcatttga agctgagttc     4020

cattactggt gattgaagta ttttcaggag cagatacatg tggtgcatgt tatatgcact     4080

tagtttgaaa gtatccctca cccaaaaagt gcagaacctc tgaaaggtga gccgtggtgc     4140

aggtgccccc ctcgctgttc gggtcagttc ttggccatgc ttggcctgtc acacgccggg     4200

tctcaacaac atcgtgcgag gagacagtga ctggtttcag cccaagagtc aactgttgag     4260

catgacatca ggaagcctgt actgtcctga tcccaccagg cttgggttaa tttcctattg     4320

cttcagagaa agagaggcgc tcttgtgctt ttgagagagc tctcatgtta aaaagaggtt     4380

gtctttgcac tgcgcttggt atgatttgtt ttcttataaa acaggaagag aacctagaat     4440

gtgcctttcg tgaaggtctg acaaatgggg tctcagagtc ctaggacccg caccaaggtc     4500

agagtccacc tgtagaggct gagcatttct acatgcaccc agggtgctgg gctgaggcta     4560

agggtggacg cgtagacccc atcacaggct tccttcctga gcccaagtcc cccatttggt     4620

cactatccct tctcagagca agtggattct cttttcctca cttggagtat tcaatgttga     4680

agtagtggcc tggagtggcc tttccctcag ctgcctgtct gggctccctg gcttcccgga     4740

tcttcatctc atacgtgagg caataggagg agtttctatt cattgagaca aacagtgagc     4800

gggcaccaac aggccagcag cttggccctt ttcacagagg tggccttgga gtctggagtc     4860

tgggcagctg tctgcctctc tacggctctg cttcccagcg ggcacacggg tccggagcct     4920

cagaatgaag tggtgcagag gcgcagggca cacctaggag aagctcaatg accaccaaag     4980

cccttgagga gagacggggt ttgctgtgtt agagaaatgg caacccccag gaccatgcac     5040

ggctctggca gtgcacagtg gctgattttc accagttcct cctacccctg cctctgtcgg     5100

agactagaaa acattctacc ccttcaggtc ttcttttaaa agaaaagagc tatggcaaag     5160

cgtgccatac aaagttaaaa aaaggaagag tggctttgcg ttcttgacca tggccacaat     5220

tctggtcact tctagcatct gaccttgaga acggtgtaga gtctctgagc caccgctggc     5280

ctttgagaga gtctcactct ccagctagct ctttgtgtag tgtccagggc cccggcagtc     5340

aggatagagc gagcaaaaga agatggacag tggacagggc gcagtggctc acgcctgtaa     5400

tcccagcgct ttgggagagc gaggcgggca gatcacaagg tcaagagatc aagaccattc     5460

tggccaacat ggtgaaaccc tgtttctact aaaaatacaa aaattagctg ggcatggtgg     5520

tgcgtgcctg taatcccagc tactcgggag gctgaggcag gagaatcgct tgaacccggg     5580

aggcagaggt tgcagtgagc cgagatcgtg ccactgcact ccagcctggg tgacagagca     5640

agactccgtc tcaaaaaaga tggccatgct ggccaaggct gggctcatag gaaatatctg     5700

tagtaggatg aaaggaatct ggcctaggga gccccggact cggtttacct accccgtact     5760

catcccactc atctgtctac cctagtgtcc atcatgccct ggatgaatcg taggtgggag     5820

ggacagaagc cgagaacacc aggcacacgg ggtgggggga atggggggag cccaggtgat     5880

cccctttgga aagtggattg atcctctccc ctgtggaatg acagcttaac ctgattaacc     5940

cactggggct tgctatttta tgagcatttt taaacagaaa ggaaagatga tatcccagtg     6000

caggtagact ttatttttga aagcatcgtg gcccctcacc tctccctctc ccccagaacc     6060

ttggccagaa ttgagtcttc gcgttgggga ggccacgctg gaaccattgc tctagggctg     6120

aaggtggaag tagggccact gccgcagctt cagccagagc cctcgctgct tcgcagaatt     6180

taacaagcac acgactggga ttcctttgga tatgagaaag gaaggcaagt gcgggcaaag     6240

ggaagctcct cccgtttttc ataaacagaa gtaagatgtc ctctttccca ggtttgcaca     6300

atcacttctg gcaaattaat tgaaggtcct tgaattcagc cagtgcacga aacctttgca     6360

tgttcttctg aaactgtact tcttccctat tctgtctacc cacactctgc gaactttgcc     6420

ttttccttaa acacattcca gaccaaacac tgttcagttt gttaaaaaaa aaaaaaaaaa     6480

aaaaagatgt atatacctgt atgtgatcca ccaccctttt gaggggcacc tggtcctcgg     6540

ttggggctgc aggtgtgcct gacatttgca aaagatattc cagtctttcg atgttcagaa     6600

ttgaaaatgt ggagatagaa aagctcaaac agactcctaa aaggagggtt tctttcctga     6660

agactccaag aaaatgagtg tgcagatgag ttagcttgac aacctcaact ctggggagca     6720

ggcaggcggt ctgaggaaga taagggccca cgccccactc acctggcacc tgttcggtgg     6780

tcccggggca tcatggtctg cagctctggg cccccagccc cactgtgaag tcagtcctgc     6840

atgctggccg aggcccggcc acctcccgat gcctccagag tcagtgggaa ggagtcagcc     6900

cttcccagac ttccccgcca cctccagcag gagcagctca gtttgtggct ctgggagctc     6960

cgcttttgca aacccaaaaa ggctgtgcat ttggaagcca aacgctcagc atgcggctgc     7020

cgagtctggt tttgtggaca aagcaaactg tggaatggct tctcggtgtc tgtataaagg     7080

gacaaacggt tgcattcacc ctttgtacta taacaccgct tctgcattcg ccatatccgt     7140

tttttaacct ttttgtctcc ggggaacttc tcattcgatt attatgtctt ctgatgattt     7200

gccatgttat tttaaaggtg attttatttt cttatggaca ggaaaaaaga aaatgaggag     7260

gagttggttt tactcttaga gataagactt cagcaggggc tcagaaaccc caaactctag     7320

ttaaattgct tctcggagga aaatcttaat ctagacagat tcagattccc aggctctcct     7380

ggaagccctg cacttcaggg cacaggggcc ctgggacgtg gttggcagcc aggctgcgag     7440

agagctaaaa aggaacaaga acatcagctc ggatgtttgt ctctcagccc tgacacctgc     7500

cactctcctt cccggggcac ttggccctat cagagggaca tgaaatgctg tccgaatggt     7560

ggcagaaatg cagcgacatt gcatgcagca gagtctttgc ttcgaaagat ggggcgccat     7620

gtttcagaga acatttatct tagtcccacg ttcaggtgag aagacctcaa aggtaccctc     7680

tgtccagaat aaacattgga acaatctctc aattggcttt tgtcactaca cataatgtaa     7740

tctcccttct ttcagctccc ccaacagtga gcatgcttcc caaaaaatta caacatcaaa     7800

accaggaatg tccccgcatc tactattacc aggcttgcaa ttggttcaat tttcccataa     7860

aaacatgttt gtccaaaaga agggaaactg tgaatttatt ccatgcatgt aataaactct     7920

gcaagaagtt taacccacat aggtttgcgg cactgcaaaa ttgttcatgg gtctatgtag     7980

caaatgattc tctgccttga caatcatgta tacatatcaa gatttctatc ataatgataa     8040

tgagattgat gacttcctgt tttcctccaa taaagacaat taatcacctt caaaaaaaaa     8100

aaaaaa                                                                8106


<210>  763
<211>  3625
<212>  DNA
<213>  homo sapiens

<400>  763
aagtgggcgc acagtggctt ccgggcccgg acgccatttc cagcggttgc tggttctgac       60

gggttgtagt ctgccaggac aatgagttat gactaccatc agaactgggg ccgtgatggg      120

ggtccccgca gctccggtgg gggctatgga ggggggccag cagggggtca tggaggtaac      180

cgaggctccg gaggaggcgg cggcggcgga gggggtggtc gaggcggcag gggccggcat      240

cccgggcacc tgaaaggccg cgaaatcggc atgtggtacg cgaaaaaaca ggggcagaag      300

aacaaggaag cggagaggca agagagagct gtagtacaca tggatgaacg acgagaagaa      360

caaattgtac agttactgaa ttctgttcaa gcgaagaatg ataaagagtc agaagcacag      420

atatcctggt ttgctcctga ggatcatgga tacggtactg aagtttctac taagaacaca      480

ccatgctcag agaacaaact tgacatccag gaaaagaagt tgataaatca agaaaaaaaa      540

atgtttagaa tcaggaacag atcatatatt gaccgagatt ctgagtatct cttgcaagaa      600

aatgaaccag atggaacttt agaccaaaaa ttattggaag atttacaaaa gaaaaaaaat      660

gaccttcggt atattgaaat gcagcatttc agagaaaagc tgccttcgta tggaatgcaa      720

aaggaattgg taaatttaat tgataaccat caggtaacag taataagtgg tgaaactggt      780

tgtggcaaaa ccactcaagt tactcagttc attttggata actacattga aagaggaaaa      840

ggatctgctt gcagaatagt ttgtactcag ccaagaagaa ttagtgccat ttcagttgcg      900

gaaagagtag ctgcagaaag ggcagaatct tgtggcagtg gtaatagtac tggatatcaa      960

attcgtctcc agagtcggtt gccaaggaaa cagggttcta tcttatactg tacaacagga     1020

atcatccttc agtggctcca gtcagacccg tatttgtcca gtgttagtca tatcgtactt     1080

gatgaaatcc atgaaagaaa tctgcagtca gatgttttaa tgactgttgt taaagacctt     1140

ctcaattttc gatctgactt gaaagtaata ttgatgagtg caacattgaa tgcagaaaag     1200

ttttcagaat attttggtaa ctgtccaatg atacatatac ctggttttac ctttccggtt     1260

gtggaatatc ttttggaaga tgtaattgaa aaaataaggt atgttccaga acaaaaagaa     1320

cacagatccc agtttaagag gggtttcatg caagggcatg taaatagaca agaaaaagaa     1380

gaaaaagaag caatatataa agaacgttgg ccagattatg taagggaact gcgaagaagg     1440

tattctgcaa gtactgtaga tgttatagaa atgatggagg atgataaagt tgatctgaat     1500

ttgattgttg ccctcatccg atacattgtt ttggaagaag aggatggtgc gatactggtc     1560

tttctgccag gctgggacaa tatcagcact ttacatgatc tcttgatgtc acaagtaatg     1620

tttaaatcag ataaattttt aattatacct ttacattcac tgatgcctac agttaaccag     1680

acacaggtgt ttaaaagaac ccctcctggt gttcggaaaa tagtaattgc taccaacatt     1740

gcggagacta gcattaccat agatgatgtc gtttatgtga tagatggagg aaaaataaaa     1800

gagacgcatt ttgatactca gaacaatatc agtacaatgt ccgctgagtg ggttagtaaa     1860

gctaatgcca aacagagaaa aggtcgagct ggaagagttc aacctggtca ttgctatcat     1920

ctgtataatg gtcttagagc aagtcttcta gatgactatc aactgccaga aattttgaga     1980

actcctttgg aagaactttg tttacaaata aagattttaa ggctaggtgg aattgcttat     2040

tttctgagta gattaatgga cccaccatca aatgaggcag tgttactctc cataagacac     2100

ctgatggagc tgaacgcttt ggataaacaa gaagaattga cacctcttgg agtccacttg     2160

gcacgattac ccgttgagcc acatattgga aaaatgattc tttttggagc actgttctgc     2220

tgcttagacc cagtactcac tattgctgct agtctcagtt tcaaagatcc atttgtcatt     2280

ccactgggaa aagaaaagat tgcagatgca agaagaaagg aattggcaaa ggatactaga     2340

agtgatcact taacagttgt gaatgcgttt gagggctggg aagaggctag gcgacgtggt     2400

ttcagatacg aaaaggacta ttgctgggaa tattttctgt cttcaaacac actgcagatg     2460

ctgcataaca tgaaaggaca gtttgctgag catcttcttg gagctggatt tgtaagcagt     2520

agaaatccta aagatccaga atctaatata aattcagata atgagaagat aattaaagct     2580

gtcatctgtg ctggtttata tcccaaagtt gctaaaattc gactaaattt gggtaaaaaa     2640

agaaaaatgg taaaagttta cacaaaaacc gatggcctgg ttgctgttca tcctaaatct     2700

gttaatgtgg agcaaacaga ctttcactac aactggctta tctatcacct aaagatgaga     2760

acaagcagta tatacttgta tgactgcaca gaggtttccc catactgtct cttgtttttt     2820

ggaggtgaca tttccatcca gaaggataac gatcaggaaa ctattgctgt agatgagtgg     2880

attgtatttc agtctccagc aagaattgcc catcttgtta aggaattaag aaaggaacta     2940

gatattcttc tgcaagagaa gattgaaagt cctcatcctg tagactggaa tgacactaaa     3000

tccagagact gtgcagtact gtcagctatt atagacttga tcaaaacaca ggaaaaggca     3060

actcccagga actttccgcc acgattccag gatggatatt acagctgaca gcttttcagg     3120

ggtggtctga aaagccagtt tgacagccat tcttcatcat tgtttaaatt ttggctggat     3180

gccaaaccct gggacatgaa caattttcat gtgtaaggta gaagccttca gtaggtagta     3240

aagacttaat gtgcatgact tgatgttata tgtagagata tatatatata tatatatata     3300

ccataaaagc aatatgttct ctgatcatat actctgctgt ggtcatgccc actctttggg     3360

agtatattcc ctttatatat attgagtatt gtaccacttg agaaattcct ttgttctgtt     3420

atacaaaatt aatctttctg ctcataatga ttgatgatac caccagtaaa aataggatgt     3480

ttaccccaaa acaagtgtca attaagaatt tgaacacaac cacatttttt aaaatgaaac     3540

ttctatcgga agtaaattaa tttgttgtaa taaagtccag tatttaataa aatgtacaat     3600

gttaaatctc aaaaaaaaaa aaaaa                                           3625


<210>  764
<211>  4903
<212>  DNA
<213>  homo sapiens

<400>  764
gtcgtttgcg gcggcgcagg cgcggtgcgg gcggcggacg ggcgggcgct tcgccgtttg       60

aatggctgcg ggcccgggcc ctcacctcac ctgaggtccg gccgcccagg ggtgcgctat      120

gccgtcggga ggtgaccagt cgccaccgcc cccgcctccc cctccggcgg cggcagcctc      180

ggatgaggag gaggaggacg acggcgaggc ggaagacgcc gcgccgcctg ccgagtcgcc      240

cacccctcag atccagcagc ggttcgacga gctgtgcagc cgcctcaaca tggacgaggc      300

ggcgcgggcc gaggcctggg acagctaccg cagcatgagc gaaagctaca cgctggaggg      360

aaatgatctt cattggttag catgtgcctt atatgtggct tgcagaaaat ctgttccaac      420

tgtaagcaaa gggacagtgg aaggaaacta tgtatcttta actagaatcc tgaaatgttc      480

agagcagagc ttaatcgaat tttttaataa gatgaagaag tgggaagaca tggcaaatct      540

acccccacat ttcagagaac gtactgagag attagaaaga aacttcactg tttctgctgt      600

aatttttaag aaatatgaac ccatttttca ggacatcttt aaataccctc aagaggagca      660

acctcgtcag cagcgaggaa ggaaacagcg gcgacagccc tgtactgtgt ctgaaatttt      720

ccatttttgt tgggtgcttt ttatatatgc aaaaggtaat ttccccatga ttagtgatga      780

tttggtcaat tcttatcacc tgctgctgtg tgctttggac ttagtttatg gaaatgcact      840

tcagtgttct aatcgtaaag aacttgtgaa ccctaatttt aaaggcttat ctgaagattt      900

tcatgctaaa gattctaaac cttcctctga ccccccttgt atcattgaga aactgtgttc      960

cttacatgat ggcctagttt tggaagcaaa ggggataaag gaacatttct ggaaacccta     1020

tattaggaaa ctttatgaaa aaaagctcct taagggaaaa gaagaaaatc tcactgggtt     1080

tctagaacct gggaactttg gagagagttt taaagccatc aataaggcct atgaggagta     1140

tgttttatct gttgggaatt tagatgagcg gatatttctt ggagaggatg ctgaggagga     1200

aattgggact ctctcaaggt gtctgaacgc tggttcagga acagagactg ctgaaagggt     1260

gcagatgaaa aacatcttac agcagcattt tgacaagtcc aaagcactta gaatctccac     1320

accactaact ggtgttaggt acattaagga gaatagccct tgtgtgactc cagtttctac     1380

agctacgcat agcttgagtc gtcttcacac catgctgaca ggcctcagga atgcaccaag     1440

tgagaaactg gaacagattc tcaggacatg ttccagagat ccaacccagg ctattgctaa     1500

cagactgaaa gaaatgtttg aaatatattc tcagcatttc cagccagacg aggatttcag     1560

taattgtgct aaagaaattg ccagcaaaca ttttcgtttt gcggagatgc tttactataa     1620

agtattagaa tctgttattg agcaggaaca aaaaagacta ggagacatgg atttatctgg     1680

tattctggaa caagatgcgt tccacagatc tctcttggcc tgctgccttg aggtcgtcac     1740

tttttcttat aagcctcctg ggaattttcc atttattact gaaatatttg atgtgcctct     1800

ttatcatttt tataaggtga tagaagtatt cattagagca gaagatggcc tttgtagaga     1860

ggtggtaaaa caccttaatc agattgaaga acagatctta gatcatttgg catggaaacc     1920

agagtctcca ctctgggaaa aaattagaga caatgaaaac agagttccta catgtgaaga     1980

ggtcatgcca cctcagaacc tggaaagggc agatgaaatt tgcattgctg gctccccttt     2040

gactcccaga agggtgactg aagttcgtgc tgatactgga ggacttggaa ggagcataac     2100

atctccaacc acattatacg ataggtacag ctccccacca gccagcacta ccagaaggcg     2160

gctatttgtt gagaatgata gcccctctga tggagggacg cctgggcgca tgcccccaca     2220

gcccctagtc aatgctgtcc ctgtgcagaa tgtatctggg gagactgttt ctgtcacacc     2280

agttcctgga cagactttgg tcaccatggc aaccgccact gtcacagcca acaatgggca     2340

aacggtaacc attcctgtgc aaggtattgc caatgaaaat ggagggataa cattcttccc     2400

tgtccaagtc aatgttgggg ggcaggcaca agctgtgaca ggctccatcc agcccctcag     2460

tgctcaggcc ctggctggaa gtctgagctc tcaacaggtg acaggaacaa ctttgcaagt     2520

ccctggtcaa gtggccattc aacagatttc cccaggtggc caacagcaga agcaaggcca     2580

gtctgtaacc agcagtagta atagacccag gaagaccagc tctttatcgc ttttctttag     2640

aaaggtatac catttagcag ctgtccgcct tcgggatctc tgtgccaaac tagatatttc     2700

agatgaattg aggaaaaaaa tctggacctg ctttgaattc tccataattc agtgtcctga     2760

acttatgatg gacagacatc tggaccagtt attaatgtgt gccatttatg tgatggcaaa     2820

ggtcacaaaa gaagataagt ccttccagaa cattatgcgt tgttatagga ctcagccgca     2880

ggcccggagc caggtgtata gaagtgtttt gataaaaggg aaaagaaaaa gaagaaattc     2940

tggcagcagt gatagcagaa gccatcagaa ttctccaaca gaactaaaca aagatagaac     3000

cagtagagac tccagtccag ttatgaggtc aagcagcacc ttgccagttc cacagcccag     3060

cagtgctcct cccacaccta ctcgcctcac aggtgccaac agtgacatgg aagaagagga     3120

gaggggagac ctcattcagt tctacaacaa catctacatc aaacagatta agacatttgc     3180

catgaagtac tcacaggcaa atatggatgc tcctccactc tctccctatc catttgtaag     3240

aacaggctcc cctcgccgaa tacagttgtc tcaaaatcat cctgtctaca tttccccaca     3300

taaaaatgaa acaatgcttt ctcctcgaga aaagattttc tattacttca gcaacagtcc     3360

ttcaaagaga ctgagagaaa ttaatagtat gatacgcaca ggagaaactc ctactaaaaa     3420

gagaggaatt cttttggaag atggaagtga atcacctgca aaaagaattt gcccagaaaa     3480

tcattctgcc ttattacgcc gtctccaaga tgtagctaat gaccgtggtt cccactgagg     3540

ttagtctctt gtattaaact cttcacaaaa tctgtttagc agcagccttt aatgcatcta     3600

gattatggag cttttttcct taatccagct gatgagttac agcctgttag taacatgagg     3660

ggacattttg gtgagaaatg ggacttaact ccttccagtg tccttagaac attttaattc     3720

atcccaactg tctttttttc cctaccattc agtgattact gtcaaggctg cttagaatcc     3780

aaacttggat ttttgactct ggcaaagctt ttagaaatac tgcaagaaaa tgatgtgtac     3840

ccaaacgtga gcataggagg cttctgttga cgtactccaa cagaagaact gtgtttcaag     3900

ttcaatccta cctgttttgt ggtcagctgt agtcctcata aaaagcaaaa caaaaattag     3960

gtattttgtc ctaaaacacc tggtaggagt gtgtgatttt ttgcattcct gacaaaggag     4020

agcacaccca ggtttggagg tcctaggtca ttagccctcg tctcccgttc cctttgtgca     4080

catcttccct ctccccattc ggtgtggtgc agtgtgaaaa gtccttgatt gttcgggtgt     4140

gcaatgtctg agtgaacctg tataagtgga ggcactttag ggctgtaaaa tgcatgattt     4200

tgtaacccag attttgctgt atatttgtga tagcactttc tacaatgtga actttattaa     4260

atacaaaact tccaggctaa acatccaata ttttctttaa tgcttttata tttttttaaa     4320

atgttaaaac ccctatagcc accttttggg aatgttttaa attctccagt tttttgttat     4380

atagggatca accagctaag aaaagatttt aatcaagttg aattgagggg attaatatga     4440

aaacttatga cctcttcctt taggagggag ttatctaaaa gaaatgtcta ttaaggtgat     4500

atatttaaaa atatttttgg gtgttcctgg cagtttaaaa aaattggttg gagaatttag     4560

gtttttatta gtaccatagt accatttata caaattagaa aatgttattt aacagctgaa     4620

ttatctatac atatctttat taatcactat tgttccagca gttttcaagt caaattaata     4680

atcttattag ggagaaaatt caattgtaaa ttgaatcagt ataaacaaag ttactaggta     4740

acttcatatt gctgagagaa atatggaact tacattgttc aattagaata gtgttctgca     4800

aaaatattta taaaacttct caagatactg ctactgtaat tttatatgaa gataagtgta     4860

tttttcaata aagcatttat aaattaaaaa aaaaaaaaaa aaa                       4903


<210>  765
<211>  2594
<212>  DNA
<213>  homo sapiens

<400>  765
gtgtgtgtct gagggtgtgt gtgtgagtgt ggctggcccc agtacctggc caagcccacc       60

acttccacct gggccctaca cccccacaat gtgtacccct cttatctgcc ctggagcctg      120

tacagccatg ccacgctacc cctgagagtc tagaaagctg gtcactaact ttgcagacgg      180

atgagccttg agcacccaga ggagactggg gctgtcaacg ctgccccttg tcctgccggc      240

ttggatcccc tgacagggtc cttctaggct tcagactggc accctgacca tggaaccctg      300

aagtggcagt gacttctaga gctcagtggc agaccccacg acccttcctc ccccttcctc      360

cccctcccac caccagcttt caagctccca gagggagggg tggggagggg atcctgatct      420

cacagggcag ggggcttcca tcatgatgct caactcagac accatggagc tggacctgcc      480

gcccacccac tcagagactg agtcgggctt cagtgactgt gggggcgggg cgggccctga      540

tggtgccggg cctgggggtc cgggaggggg ccaggcccga ggcccagagc cgggagagcc      600

tggccggaaa gacctgcagc atctgagccg cgaggagcgc cggcgccggc gccgcgccac      660

agccaagtac cgcacggccc acgccacgcg agaacgcatc cgcgtggaag ccttcaacct      720

ggccttcgcc gagctgcgca agctgctgcc tacgctgccc cccgacaaga agctctccaa      780

gattgagatt ctgcgcctgg ccatctgcta tatctcctac ctgaaccacg tgctggacgt      840

ctgaactcag cctgtctccc acctcccggg cctctctggg gcccctttcc accgctcact      900

gcttagaaag gccgcatcct ccccgagccc ttataccttg gcatggagtc ccaaaggccc      960

tgggcacagg cagagagccc accggctggt catgagggcc tcttcctttc tctgacccag     1020

gcacctcgag ggctattctc ctgggttcct tccggggttt attgctgagg cccagctgtg     1080

cagaattgtt tgctagtgtg gttggtatgg aatccttgct ggctttacta agccagccac     1140

acttggagtc tgcccccaag ctctctcact gaatgctgcc tcttctaccc ctatgtccaa     1200

attttcagcc accacagacc tcagctgtgt atcctatctg ttctagcttc tcctgcccct     1260

ggtggggatg ggctgtcaga attgcaaggg aggaaggctg gggttagagt ggggagtggg     1320

cttcttcctc caagatctca gtctctcagt gcttggcaga ggggtgaggc cctggggagg     1380

caggggttgg tgccctgact cctgtgaggg gaatctcagt agctgggaat tatggaaaaa     1440

ctcttcctgt ttctgtccat cttgttcctg tggcttagca catacagacc tcagatctta     1500

cttggtagtg agtgccttgc cctctttgag ctatttggct acttccctgt ccctctgact     1560

cctactgtcc caattttctc cctccctgtg tgtcactaga gaaaaaaaaa aacaaaaacc     1620

tagattccgg attaggggat gacatcccaa acagcccgga gtatttgcag aaggctcagg     1680

caacgagtgg gccacatctc acttctgctt cctcatctca gcccactctg aaaatgtgca     1740

gcaccctcac tggttcctcc ccccaacgca aggaggatgc ccaattgttg ccctctgaaa     1800

atgcacagtt ctcctggccc taggacttac ttattacatt tttttctctt tccttgagct     1860

gcctttggca agggaagaga cccccaactc tgcgccccta ctccatgctg ctgatcccca     1920

cctgcgcact atagctcagg gtcagcagtg gaatgaaggg ccttagaacc tgcatagaag     1980

aaatgaactc actgcatttc tgtgctccct cctccctcgc accaaactcc tagctctaca     2040

agtatattta tttatttatt tatttattca tctatttatt tacttattta tttatttata     2100

aatattgcta tttattgccg agttgtgcac tttggggtag agtgaggggc tcccagcagc     2160

tctagctggg tctctcttgc ttcctccctg cttacgcctt tccttttctt gctccttctt     2220

caactcctgg tgtgtgtgag catgcccttt gcttgccaca ccatatcctt tccccagatc     2280

cacctgtcct gacactctag tcctccagga tagtgctcct cccccagctc cagggctcct     2340

ggatgtcctt cctcaactcc ctccacccct agacaatcct acctggtccc atctgcctct     2400

tttctctccc cagcctgccc tgtgaccctt gcctcttcct gatactccca agagcaggcc     2460

ccaggggtct gtgtcacata tctctgtgtg attccttctg gttgcatccc caatttcata     2520

caaaaagaaa aataaaagtg acctcgttct agcaccagga aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaa                                                       2594


<210>  766
<211>  4494
<212>  DNA
<213>  homo sapiens

<400>  766
accagactgg ccgcctctcg gcgagcgcgc cactctcccg tcgccgctga cccgcgcgcg       60

gccgccgaag cctccccgcg gggacattca ttcttgcccc ttgcctgtcg ccgggccggg      120

cgtacgggcc gcgttgtcgg gggttttgtc ccctttttcc tctttttttt ttccttctcc      180

gccccccccc cttttttttt tttttgcttt ttttttcctt tctgtttttg ttgttgttct      240

tgcctatgtt cgggaaacca gacaaaatgg acgttcgatg ccactcggac gccgaggctg      300

cccgggtctc gaagaacgcg cacaaggaga gtcgggagag caagggcgcg gaggggaacc      360

tcccagccgc cttcctcaag gagccgcagg gcgccttctc agcgtcgggc gctgctgagg      420

attgtaacaa aagtaaatcc aattccgcag cggacccgga ttactgccgc cggatcctgg      480

tccgagatgc caaggggtcc atccgagaga tcatcctgcc caagggcctg gacttggacc      540

ggcctaagag gacgcgcacg tccttcaccg cggagcagct ctatcggctg gagatggagt      600

tccagcgctg ccagtacgtg gtgggccgcg agaggaccga gctcgcccgg cagcttaacc      660

tctccgagac ccaggcaaat agtgaagaaa ataatgaacg attcaaacgc gggataaaaa      720

aacaaaagaa gaaaaggaag aaagagccag caaatgatga gtctcggcgt ggggactccg      780

ggggcagagg gtggcagccc ctatagtgcg gggccctgcg actggtaccg tgagcgcctg      840

ggatgaggtt tgggcggatt tcgggtttcc ggagaggcag agacgcctgg ctacgacgat      900

ttgttccact tccttgagtg tttcgctctc gatttctcta tctgtccctc tgaggtcggc      960

ccctcagacc ctcctcctta atttcccact gcgtaattct tagtttattt aggaactcat     1020

ctctgggcac tataaagtct ctgcctccta atgctaggtt tctagagtct tccagctgca     1080

tcttcatgcc ggcagcattt tggattttgt gcaatcatgg gcccagaata ggcaaggttt     1140

tattttcttc tgacttagaa tataagtctc gccatcgtca aagagaaact ttgaaggagc     1200

aggagactga aatcgatatt aattcctgca aagagacctc ctcaccctgg tgcttatgcg     1260

gtggtgacgg gtgtagacgt tgcaaacaaa tcttgggaag cgaggagggc cggggaggac     1320

acttccggac acgctcttct aaagcgtgtg cagcacgggg cgaagtccgc gctgcggggg     1380

cagcggcccc ggctccttct tgtagcgcct gcacacctgg gtgttgcagg gacccgcagc     1440

tcccgtgcgg caccggccct agccaggcct tactgcccct actcgtgtac tgtgcctgaa     1500

gctgaagttg gaggcatcca aaataaggcg gggcacagtg tgggcggcgg agtccctgag     1560

ccttgagctc cgctttttgc tgagatcaca gcagccgccc acagacagtt cacttttatt     1620

tctcaaagtt gctgcagatc cctcagcttg gcttctcttg gctcttcccc tccctgtccg     1680

cctctcctta ctttctcttg cttgaaactg cttttccttt tctactcttt tcttccgcgc     1740

tcctgtcccg taaacgcctg cgcttccttt aaggagttct ctctctgtgg tgtgggctcc     1800

cctctcgttc cccctgtctc cctcctccat tacttcttcc ttccaggtct ctctctctct     1860

tttggttttc tggttttttt ctcctgctca aggggtccca aaggccaagg cagtgggtgg     1920

ctctcgctgc agcttcaagg ctggtggctg ggaccctcca ggggtgagaa ggaagggaga     1980

aggtggcata actttttgga acaaaagaaa acacaaaatc ctagcttggg attcccaaca     2040

aattcagcct cctctcccag gggcctcagc ctgggaagtc accaagcaga tccctccttc     2100

cagcttcctg ctctttctcc tttttgcttt cttacccctg aaagagggaa ggacaagtca     2160

cctcataact tctgctctca cctcccttcc ctccctggct ttgggaagag ctgctgagct     2220

ctttgcctgc cactcaggga gtgcaattgt tcttaaagag cctcttctgc atagaaaaag     2280

aattgcaatt ttaatttaaa aacatttata gaaaattcat ttaattttag tgactatctt     2340

cttttccctc cttccccaag ggcctccagt aagctgcctt ggtccctgga ggcttctggc     2400

ttccaactgg agactcacag gccttggagg aggaggcagg taccctctat gccaatagct     2460

gggcctgcct ggggaaaggt ggaaggagaa acagctgcag gaggggggag ctgaaaggaa     2520

tctgatgctc aggcctgcac aaagcaaccg ccaaattgtt tcagagcaga aaagaaaaag     2580

ggagaaaacc tcttagcaaa gccctgtgag tttgggggtc aggttcaaga aagatgtggg     2640

aagtcacttg gagagctaaa cgggacacat gctcctatcc acacttgcag ttggtctaac     2700

cttcagccag aatgtattca taagtagcat ttggcaaccc tttatagttt acaaatagca     2760

ttttacatac accattctac tattcctcat ggtggctttg ggaggtccag ctccgtttta     2820

aagactcaca caggactgaa gcaaataact tgctcaaagc cacatagctg ctcagaaccc     2880

aagattgtaa gctcccccta gggccagagg cctctttctt tcagtttttt tctttcgtcc     2940

ccctttgacc cctctttcct tcttcccttt ctcccctcct tcctcctttc cttctttttg     3000

tgcccacagt gtctggatca tggtacctga attctttagc ctatttgcac ccacatctgc     3060

taatgtccat atctagccat ctattacacc agctgctgag gatttacttg gtgccctcat     3120

caagaagttt gaatttctcc ctccttcctt tttttttcct gccactgtcc caactctttc     3180

cctctacgtc tctctagaat gacatcttta aaccccttac actctttggt cttacacatc     3240

cttaaaaatg attatttata aattgaatta taatatccat gaggtaaaca ctcatagggt     3300

aaagtacaca aagcttaact atacaagttg atgatttaca cacacacaca cacacacaca     3360

cacacacccc ttcttgaatg gctccaagga taccctttta acttcttccc ttcagccaca     3420

taagccatat gatgacacac agtgtctttc tcctgtttga aaagaaattg tgtcatattg     3480

gtgtgctgtt cttgcataga aagccttttt taagaagtct ttttaagatt tcttgaagga     3540

ttttagaaat catatatctc ttctaacccc ctgaaatcct gagtttaagt ggcttgatta     3600

aatggctgat caaaacttaa aaacacacta ggtcaatgtt tttcaagata caactgagga     3660

ccagctgctt cagaatcatc tggggactgg ctaaaattcc aggttcctaa gccctagtcc     3720

catctgatga atcagaaact aggttggggc ttaggaacgt gcattttaaa cacttttcca     3780

aagtgattct tatccagact aatatttgag aagtactgta ttaaatggca aactcccaaa     3840

acactgcagc ctcctgcatc tggcccaggg cctggcattt ggtaggaata caatgaatgt     3900

ttgttaaaca aattaatcca cagtttctga cacagtttag aatttcttgg accacattat     3960

gctattgtaa tttaacacca tttctacgtc gggaaatctt tacatttcag tctttttcat     4020

tttcatggag gtttcatttt aatggagcag gagagaaaag agagatctac tttggtggtt     4080

tctcaggtct cagggaaggt cttttataaa ctcaatgggg accaccttcc tggagaggct     4140

gctcccttac agacctggta gtttggggaa aggaggagga gagcccttca ggtttgctga     4200

aaagcattca gatgcacacc cttcttggtt ggaactgaaa gcttctgttt gaagagacat     4260

gagttctgga aggagcaagg ccaccaggtc cagagaacct ggcatgcaat ggacatggaa     4320

gctgaaaatt acttgggtat tctctgattt ctagctaata tgaaaataat tttctttcta     4380

gaaacacatt tgcctatctt cttaccctga aacagaaaat aaatattgtg ctttatgtgg     4440

tagtgttgta cccattctta aaaataaatc acatcatata tatgtgtaaa atat           4494


<210>  767
<211>  2203
<212>  DNA
<213>  homo sapiens

<400>  767
aagctttgaa ccgagtttgg ggagctcagc agcatcatgc ttagactttt caaagagaca       60

aactccattt tcttatgaat ggaaagtgaa aacccctgtt ccgcttaaat tgggttcctt      120

cctgtcctga gaaacataga gacccccaaa agggaagcag aggagagaaa gtcccacacc      180

cagaccccgc gagaagagat gaccatgacc accatgccag aaagtctcaa cagccccgtg      240

tcgggcaagg cggtgtttat ggagtttggg ccgcccaacc agcaaatgtc tccttctccc      300

atgtcccacg ggcactactc catgcactgt ttacactcgg cgggccattc gcagcccgac      360

ggcgcctaca gctcagcctc gtccttctcc cgaccgctgg gctaccccta cgtcaactcg      420

gtcagcagcc acgcatccag cccctacatc agttcggtgc agtcctaccc gggcagcgcc      480

agcctcgccc agagccgcct ggaggaccca ggtcaagatc tggttccaaa acaagcgatc      540

caagttcaag aagctgatga agcagggtgg ggcggctctg gagggtagtg cgttggccaa      600

cggtcgggcc ctgtctgctg gctccccacc cgtgccgccc ggctggaacc ctaactcttc      660

atccgggaag ggctcaggag gaaacgcggg ctcctatatc cccagctaca catcgtggta      720

cccttcagcg caccaagaag ctatgcagca accccaactt atgtgaggtt gcccgcccgt      780

ctccttcttg tctccccggc ccaggtccct cccgcctcca ggtccatcca tcccgtccgg      840

aaaagaagga cccagaggga agaaggaaca gtggaggcgg gacgccctcc atctcctcgg      900

agccccgcga ggtccggccc agcaacttcc cggcatccgc gctctagcct gaaccctggc      960

ctgggccgag cagtggcagc agagagtggc ctcggaggga agccactgcc acctgagaca     1020

gcccaagcag caagataaac ccgctccacc cgacccgccg accttcagct ttgtgggact     1080

atcaggaaaa aacaaaacaa aaacaaaatg tagaaaaagc aaaagctctt ttctgtcctg     1140

tcagtctcct gtctcctttt gctctgtctg tgcgctggta aagtccaggt cctcatccgt     1200

ccgctgtcct cattctgcgg cctcagcaaa aagccacaag gtctgagcgg cccgggtcct     1260

gccgggctga ccatctccgg atcctgggac actctgcctg accatctgtg tagctggtgt     1320

gggaatctgg gggcattgga gggagggggt tttatttatt gagaaatgga cttcgcctga     1380

ggctgtttgc caattcaggg ttctgctggg cgcaaggaac gcactgttca aacgcactgt     1440

ttactttaag cgcacgggga gaaacgaata aggaggacgt ggtgattttt aatttataca     1500

gtaacttttg tacttctctg gtatggagag tttggagccg aatgatttgc attttttaca     1560

tgtccgacat tatttaataa ataattttta aaagaaaaga acgataaatg aagccaacat     1620

gattttctca tttcgggagg aactctgttg cttcgcctgg acaagaagga aaatgctgat     1680

ttcctccttg ggtagaaaga gggagcgagg gcaaatgggg agtagagaga aaacaggcga     1740

gaacaagcac tctaattcca gtgggcttta aaataagaca aaatcagctt tacaacaatc     1800

cctagaggct cgaccacaga ataatgccag tcaccaccct gaacgcacaa tctccagtgc     1860

aggatctaat gactgtacat attattgtta ttattattat tgttattatt gttgttctgt     1920

aaacatgttg cacaagctta gcctttttgc gttctgttgt gtgtggctgt aaaaccccat     1980

gctttgtgaa atgagaatct tgacattttt cttgtgaaat ttggaaaatg tgatcaattg     2040

aaatcaactg tgttttgtgt tctctatgtc aaagtttagt tttatattga gaatgttaac     2100

ttattgcttt gtatcttggg aaaaaaactt tgtaaataag ttataaagtt tctttgagac     2160

agtaaaatta tgatttcttg aaaaaaaaaa aaaaaaaaaa aaa                       2203


<210>  768
<211>  5189
<212>  DNA
<213>  homo sapiens

<400>  768
ggactgcgaa aggagcaggg ttgcggagct agggctccag cctgcggccg cgcattcttg       60

cgtctggcca gccgcgagct ctaagggtcg gccccgcccg gtccgccccc gcggctccct      120

gccaggctct cgcgggcgcg ctcggggtgg ggcctcgcgg ctggcggaga tgcggccggg      180

gctgcgcggt ggtgatgcga gcctgctggg cggcgcgccg gggcagccgg agccgcgcgc      240

cgcggcgctg taatcggaca ccaagagcgc tcgcccccgg cctccggcca ctttccattc      300

actccgaggt gcttgattga gcgacgcgga gaagagctcc gggtgccgcg gcactgcagc      360

gctgagattc ctttacaaag aaactcagag gaccgggaag aaagaatttc acctttgcga      420

cgtgctagaa aataaggtcg tctgggaaaa ggactggaga cacaagcgca tccaaccccg      480

gtagcaaact gatgactttt ccgtgctgat ttctttcaac ctcggtattt tcccttggat      540

attaacttgc atatctgaag aaatggcatt ccggacaatt tgcgtgttgg ttggagtatt      600

tatttgttct atctgtgtga aaggatcttc ccagccccaa gcaagagttt atttaacatt      660

tgatgaactt cgagaaacca agacctctga atacttcagc ctttcccacc atcctttaga      720

ctacaggatt ttattaatgg atgaagatca ggaccggata tatgtgggaa gcaaagatca      780

cattctttcc ctgaatatta acaatataag tcaagaagct ttgagtgttt tctggccagc      840

atctacaatc aaagttgaag aatgcaaaat ggctggcaaa gatcccacac acggctgtgg      900

gaactttgtc cgtgtaattc agactttcaa tcgcacacat ttgtatgtct gtgggagtgg      960

cgctttcagt cctgtctgta cttacttgaa cagagggagg agatcagagg accaagtttt     1020

catgattgac tccaagtgtg aatctggaaa aggacgctgc tctttcaacc ccaacgtgaa     1080

cacggtgtct gttatgatca atgaggagct tttctctgga atgtatatag atttcatggg     1140

gacagatgct gctatttttc gaagtttaac caagaggaat gcggtcagaa ctgatcaaca     1200

taattccaaa tggctaagtg aacctatgtt tgtagatgca catgtcatcc cagatggtac     1260

tgatccaaat gatgctaagg tgtacttctt cttcaaagaa aaactgactg acaataacag     1320

gagcacgaaa cagattcatt ccatgattgc tcgaatatgt cctaatgaca ctggtggact     1380

gcgtagcctt gtcaacaagt ggaccacttt cttaaaggcg aggctggtgt gctcggtaac     1440

agatgaagac ggcccagaaa cacactttga tgaattagag gatgtgtttc tgctggaaac     1500

tgataacccg aggacaacac tagtgtatgg catttttaca acatcaagct cagttttcaa     1560

aggatcagcc gtgtgtgtgt atcatttatc tgatatacag actgtgttta atgggccttt     1620

tgcccacaaa gaagggccca atcatcagct gatttcctat cagggcagaa ttccatatcc     1680

tcgccctgga acttgtccag gaggagcatt tacacccaat atgcgaacca ccaaggagtt     1740

cccagatgat gttgtcactt ttattcggaa ccatcctctc atgtacaatt ccatctaccc     1800

aatccacaaa aggcctttga ttgttcgtat tggcactgac tacaagtata caaagatagc     1860

tgtggatcga gtgaacgctg ctgatgggag ataccatgtc ctgtttctcg gaacagatcg     1920

gggtactgtg caaaaagtgg ttgttcttcc tactaacaac tctgtcagtg gcgagctcat     1980

tctggaggag ctggaagtct ttaagaatca tgctcctata acaacaatga aaatttcatc     2040

taaaaagcaa cagttgtatg tgagttccaa tgaaggggtt tcccaggtat ctctgcaccg     2100

ctgccacatc tatggtacag cctgtgctga ctgctgcctg gcgcgggacc cttattgcgc     2160

ctgggatggc cattcctgtt ccagattcta cccaactggg aaacggagga gccgaagaca     2220

agatgtgaga catggaaacc cactgactca atgcagagga tttaatctaa aagcatacag     2280

aaatgcagct gaaattgtcc agtatggagt aaaaaataac accacttttc tggagtgtgc     2340

ccccaagtct ccgcaggcat ctatcaagtg gctgttacag aaagacaaag acaggaggaa     2400

agaggttaag ctgaatgaac gaataatagc cacttcacag ggactcctga tccgctctgt     2460

tcagggttct gaccaaggac tttatcactg cattgctaca gaaaatagtt tcaagcagac     2520

catagccaag atcaacttca aagttttaga ttcagaaatg gtggctgttg tgacggacaa     2580

atggtcccca tggacctggg ccagctctgt gagggcttta cccttccacc cgaaggacat     2640

catgggggca ttcagccact cagaaatgca gatgattaac caatattgca aagacactcg     2700

gcagcaacat cagcagggag atgaatcaca gaaaatgaga ggggactatg gcaagttaaa     2760

ggccctcatc aatagtcgga aaagtagaaa caggaggaat cagttgccag agtcataata     2820

ttttcttatg tgggtcttat gcttccatta acaaatgctc tgtcttcaat gatcaaattt     2880

tgagcaaaga aacttgtgct ttaccaaggg gaattactga aaaaggtgat tactcctgaa     2940

gtgagtttta cacgaactga aatgagcatg cattttcttg tatgatagtg actagcacta     3000

gacatgtcat ggtcctcatg gtgcatataa atatatttaa cttaacccag attttattta     3060

tatctttatt caccttttct tcaaaatcga tatggtggct gcaaaactag aattgttgca     3120

tccctcaatt gaatgagggc catatccctg tggtattcct ttcctgcttt ggggctttag     3180

aattctaatt gtcagtgatt ttgtatatga aaacaagttc caaatccaca gcttttacgt     3240

agtaaaagtc ataaatgcat atgacagaat ggctatcaaa agaaatagaa aaggaagaca     3300

gcatttaaag ttgtataaaa acatgagtta ttcataaaga gaaaatgatg agtttttatg     3360

gttccaatga aatatgttgg ggttttttta agattgtaaa aataatcagt tactggtatc     3420

tgtcactgac ctttgtttcc ttattcagga agataaaaat cagtaaccta ccccatgaag     3480

atatttggtg ggagttatat cagtgaagca gtttggttta tattcttatg ttatcacctt     3540

ccaaacaaaa gcacttactt tttttggaag ttatttattt tagactcaaa gaatataatc     3600

tggcactact cagttattac tgtttgttct cttattccct agtctgtgtg gcaaattaaa     3660

caatataaga aggaaaaatt tgaagtatta gacttctaaa taaggtgtga aatcatcaaa     3720

aagaaaaatc aaagtagaaa ctactaattt tttaagagga atttataaca aatatggcta     3780

gttttcaact tcagtactca aattcaatga ttcttccttt tattaaaacc agtctcagat     3840

atcatactga tttttaagtc aacactatat attttatgat cttttcagtg tgatggcaag     3900

gtgcttgtta tgtctagaaa gtaagaaaac aatatgagga gacattctgt ctttcaaaag     3960

gtaatggtac atacgttcac tggtctctaa gtgtaaaagt agtaaatttt gtgatgaata     4020

aaataattat ctcctaattg tatgttagaa taattttatt agaataattt catactgaaa     4080

ttattttctc caaataaaaa ttagatggaa aaatgtgaaa aaaattattc atgctctcat     4140

atatatttta aaaacactac ttttgctttt ttatttacct tttaagacat tttcatgctt     4200

ccaggtaaaa acagatattg taccatgtac ctaatccaaa tatcatataa acattttatt     4260

tatagttaat aatctatgat gaaggtaatt aaagtagatt atggcctttt taagtattgc     4320

agtctaaaac ttcaaaaact aaaatcattg tcaaaattaa tatgattatt aatcagaata     4380

tcagaatatg attcactatt taaactatga taaattatga taatatatga ggaggcctcg     4440

ctatagcaaa aatagttaaa atgctgacat aacaccaaac ttcatttttt aaaaaatctg     4500

ttgttccaaa tgtgtataat tttaaagtaa tttctaaagc agtttattat aatggtttgc     4560

ctgcttaaaa ggtataatta aacttctttt ctcttctaca ttgacacaca gaaatgtgtc     4620

aatgtaaagc caaaaccatc ttctgtgttt atggccaatc tattctcaaa gttaaaagta     4680

aaattgtttc agagtcacag ttccctttat ttcacataag cccaaactga tagacagtaa     4740

cggtgtttag ttttatacta tatttgtgct atttaattct ttctattttc acaattatta     4800

aattgtgtac actttcatta cttttaaaaa tgtagaaatt cttcatgaac ataactctgc     4860

tgaatgtaaa agaaaatttt ttttcaaaaa tgctgttaat gtatactact ggtggttgat     4920

tggttttatt ttatgtagct tgacaattca gtgacttaat atctattcca tttgtattgt     4980

acataaaatt ttctagaaat acactttttt ccaaagtgta agtttgtgaa tagattttag     5040

catgatgaaa ctgtcataat ggtgaatgtt caatctgtgt aagaaaacaa actaaatgta     5100

gttgtcacac taaaatttaa ttggatattg atgaaatcat tggcctggca aaataaaaca     5160

tgttgaattc cccaaaaaaa aaaaaaaaa                                       5189


<210>  769
<211>  1427
<212>  DNA
<213>  homo sapiens

<400>  769
atctccttcc gtcggtccgc tcagaatcag ctgtcctctc agactgtgtg ggtggtttcc       60

ccggccgcag ctccgtacgg gcttggattg ctgggcctcg gtgcacccca gcctccccca      120

ctcgggttct gagcttgagc tggcggctct ttaactctgc ttcactgttg ctcttggcaa      180

catccacttc cgggagcgag tgccgtttcc cccgctcacc gcgggctagg gagcgtggga      240

ttccggactg tgagcggctg ttagtgcgtc gcagctgctg gcgatccggc gaccctcggc      300

cggcaggacc cgcgggccac gcagccgggg ccttctcaac gcctcagtac ctcggcggga      360

ccgccatggt tctgctgcac gtgaagcggg gcgacgagag ccagttcctg ctgcaggcgc      420

ctgggagtac cgagctggag gagctcacgg tgcaggtggc ccgggtctat aatgggcggc      480

tcaaggtgca gcgcctctgc tcagaaatgg aagaattagc cgaacatggc atatttctcc      540

ctcctaatat gcaaggactg accgatgatc agattgaaga attgaaattg aaggatgaat      600

ggggtgaaaa atgcgtaccc agcggaggtg cagtgtttaa aaaggatgat attggacgaa      660

ggaatgggca agctccaaat gagaagatga agcaagtgtt aaagaagact atagaagaag      720

ccaaagcaat aatatctaag aaacaagtgg aagccggtgt ctgtgttacc atggagatgg      780

tgaaagatgc cttggaccag cttcgaggcg cggtgatgat tgtttacccc atggggttgc      840

caccgtatga tcccatccgc atggagtttg aaaataagga agacttgtcg ggaacacagg      900

cagggctcaa cgtcattaaa gaggcagagg cgcagctgtg gtgggcagcc aaggagctga      960

gaagaacgaa gaagctttca gactacgtgg ggaagaatga aaaaaccaaa attatcgcca     1020

agattcagca aaggggacag ggagctccag cccgagagcc tattattagc agtgaggagc     1080

agaagcagct gatgctgtac tatcacagaa gacaagagga gctcaagaga ttggaagaaa     1140

atgatgatga tgcctattta aactcaccat gggcggataa cactgctttg aaaagacatt     1200

ttcatggagt gaaagacata aagtggagac caagatgaag ttcaccagct gatgacactt     1260

ccaaagagat tagctcacct ttctcctagg caattataat ttaaaaaaaa aaaaaaggcc     1320

acttactgcc ctctgtaaaa gatgttaaca tttctagttt tcttttagtg tgaattttta     1380

aaatagcagt tattcaaggt tttagaactt aataaatacc tagtcag                   1427


<210>  770
<211>  1646
<212>  DNA
<213>  homo sapiens

<400>  770
gctttctttg tgtggctgaa gcgctagaaa tggcatattt tctttccctt cgttaaaaaa       60

tcagaccctc tttcccctct ctccccgcgg gaacacagct agggagtggg taggagcagg      120

atctgccgac gagggcagag gcggaaaatc ctcgggcgat gagctgaaga gggccgggtc      180

cgggagggat gctgggagct tgactcactc gcacaccatg tgtccctccg cgcgcagcac      240

gggggacttt tcggtgggga ttttgggcgc cgaccagacg cggcattttc ggaaaatagc      300

gccctgtgca gctgaagcgc tttgtgtgta gcggggccgc gtcagcccgg ccgggtacga      360

ggcgcctcgg gtccccgcac cacctcctgc tgccttcccg tcgccgctcc cgaagctttt      420

ccaggtcaca gcatatttgt ggaggaagat gtccctggta gatttgggaa agaagctttt      480

agaagcggca cgagcaggtc aagatgatga agttcgtatt ttgatggcaa atggagctcc      540

ctttactaca gactggctgg gaacttctcc acttcatcta gcagcacagt atggtcatta      600

ttccaccaca gaggtactgc tgcgagctgg tgtgagcaga gatgccagaa ccaaagtgga      660

ccgaacacca ttacatatgg cagcttctga gggccatgcc agcatagtag aggttttact      720

taagcatggt gctgatgtca atgcaaagga catgttaaag atgacagctc tccattgggc      780

cacagaacac aatcatcaag aggtggtgga acttttaatc aaatatggtg ctgatgtaca      840

cacgcaaagt aaattttgta aaactgcatt tgatatttca atagacaatg gaaatgaaga      900

tttagcagag atattacaga ttgctatgca gaaccaaatc aacacaaacc cagagagtcc      960

tgacactgtg acaatacatg ctgcaacacc acagtttatc attggacctg gaggggtggt     1020

gaacctaaca gatgaaacgg gtgtatctgc tgttcagttt ggaaactctt ctacatcagt     1080

attagctaca ttagctgcct tagctgaagc atctgctcca ttgtccaatt cttcagaaac     1140

tccagtagtg gccacagaag aagtagttac tgcagaatct gtggatggtg ccattcagca     1200

agtagttagt tcagggggtc agcaagtcat cacaatagtt acagatggaa ttcagcttgg     1260

aaatttgcac tctattccaa ccagtggaat tggtcagccc atcattgtga ccatgccaga     1320

tggacaacaa gtattaacag taccagcaac agacattgct gaagaaactg ttataagtga     1380

agaaccacca gctaagagac aatgtatcga aataattgaa aaccgggtgg aatctgcaga     1440

aatagaagta aggagtcttt tacccggtgt gctttgccgc agtcatccaa aataaattca     1500

attttttttg tcttttatat ttattactga cagtattgtt ttgatacaga atgaaagtgc     1560

gtagtatttt cattttgttt atttttgcct tatacatata gcaagccctc aataaataaa     1620

tattgaatga atgaaaaaaa aaaaaa                                          1646


<210>  771
<211>  6314
<212>  DNA
<213>  homo sapiens

<400>  771
gtcggcgagg agggtccggc cggagttgaa ggattgaact ttccggctca gtcgcggcgt       60

ctgcctggtc ctcagcagtg cagccccggc gcggagcagg gagcctcggc ccgcgcccgg      120

cgccctcgcc ctcgccctcg acccgcagcc atggtgcccg gggtgcccgg cgcggtcctg      180

accctctgcc tctggctggc ggcctccagc ggctgcctgg cggccggccc cggcgcggct      240

gctgcgcggc ggctggacga gtcgctgtct gccgggagcg tccagcgcgc tcgctgcgcc      300

tccaggtgcc tgagcctgca gatcactcgc atctccgcct tcttccagca cttccagaac      360

aatggttccc tggtttggtg ccagaatcac aagcaatgtt ctaagtgcct ggagccctgc      420

aaggaatcag gggacctgag gaaacaccag tgccaaagct tttgtgagcc tctcttcccc      480

aagaagagct acgaatgctt gaccagctgt gagttcctca aatacatcct gttggtgaag      540

cagggggact gtccggctcc tgagaaagcc agtggatttg cggccgcctg tgttgaaagc      600

tgcgaagttg acaatgagtg ctctggggtg aagaaatgtt gttcgaatgg gtgtggacac      660

acctgtcaag tacccaagac tctgtacaaa ggtgtccccc tgaagcccag aaaagagtta      720

cgatttacag aactgcagtc tggacagctg gaggttaagt ggtcctcgaa attcaatatt      780

tctattgagc ctgtgatcta tgtggtacaa agaagatgga attatggaat ccatcctagc      840

gaagatgacg ccactcactg gcagacagtg gcccagacca cagacgagcg agttcaactg      900

actgacataa gacccagccg atggtaccag tttcgagtgg ctgctgtgaa tgtgcatgga      960

actcgaggct tcactgcccc cagcaaacac ttccgttctt ccaaagatcc atctgcccca     1020

ccagcaccgg ctaacctccg gctggccaac tccaccgtca acagtgatgg gagtgtgacc     1080

gtcactatag tttgggatct ccccgaggag ccggacatcc ctgtgcatca ttacaaggtc     1140

ttttggagct ggatggtcag cagtaagtct cttgtcccaa caaagaagaa gcggagaaag     1200

actacggatg ggtttcaaaa ttctgtgatc ctggagaaac tccagccaga ctgtgactat     1260

gttgtggaat tgcaagccat aacgtactgg ggacagacac ggctgaagag tgcaaaggtg     1320

tcccttcact tcacatcgac acatgcaacc aacaacaaag aacagcttgt gaaaactaga     1380

aaaggtggaa ttcaaacaca actccctttt caaagacgac gacccactcg cccgctggaa     1440

gtcggagctc ccttctatca ggatggccaa ctgcaagtta aagtctactg gaagaagaca     1500

gaagatccca ctgtcaaccg atatcatgtg cggtggtttc ctgaagcgtg tgcccacaac     1560

agaacaaccg gatcagaggc atcatctggc atgacccacg aaaattacat aattcttcaa     1620

gatctgtcat tttcctgcaa gtataaggtg actgtccaac caatacggcc aaaaagtcac     1680

tccaaggcag aagctgtttt cttcactact ccaccatgct ctgctcttaa ggggaagagc     1740

cacaagcctg ttggctgcct gggcgaagca ggtcatgttc tttctaaggt gctagctaag     1800

cctgagaacc tttctgcttc attcatcgtc caggatgtga acatcaccgg tcacttttct     1860

tggaagatgg ccaaggccaa tctctatcag cccatgactg ggtttcaagt gacttgggct     1920

gaggtcacta cggaaagcag acagaacagc ctacccaaca gcattatttc acagtcccag     1980

atcctgcctt ccgatcatta tgtcctaaca gtgcccaatc tgagaccatc tactctttac     2040

cgactggaag tgcaagtgct gaccccagga ggggaggggc cggccaccat caagacgttc     2100

cggacgccgg agctcccacc ctcttcagca cacagatctc atcttaagca tcgtcatcca     2160

catcattaca agccttctcc agaaagatac taaactgttc aaaaagattt tgtgaaattg     2220

cacagatgtg taagcttgtt gaacttcggc cacgagacat gcacacttcc agaggcagtg     2280

ggaactgctc agaggcccgg actctcctat gtgactttag tgcaggaaga acttctgtca     2340

atcatggacg catctggaga caagtgagaa acagtagatt ggtgaagaca gacaccagtt     2400

ccctacaagc atggagaaaa tgaagaatag gcctgtttaa tgctaaattt tgttttcatg     2460

tatggtgtcg ctcatttcta ttgaattaca acagaactca gttttccctg aatttggagc     2520

accaaactcc gccccaaaaa ggagagtaac aaatacacaa ttcacacata acactaagcg     2580

taaatctaat caataaaata tatttttgac taaattattg attcgatatg aaaaatcaac     2640

taagattaca cagctttgtt tttttgaatc tttcctaaga tcatttttat cctaggtgat     2700

ttttaaatga aaatgtgtaa tctaaaatat accagcgaat ttaaatctaa aaatgctcct     2760

actttaagta ccttgtgctg ctctttatgc aaaggtaaat caaagttccc tctataaatt     2820

atgatttaca aaagacaccc aagccagagg aactcaatga aataagctgc taatcagatt     2880

ttaccttgga gaaatgaaaa ttatttcttg gggatgcctt ttaatatttg atcctattat     2940

gtgagagatt ttcctgatat gttatcttat ttatattttc ccttattttc ctcaatgcag     3000

ataatagctt ttggtgcact tttgtttcac catctgaaaa ttcacaaaac ttcttgcttc     3060

aaatgaaaaa atcccaacta ttgagcatgt ttaaatcttt gcagagattt gccttttctt     3120

aatcaaagaa aggtctttgt gtgctagaat attattggta atgttttaaa aattcctttg     3180

attgatagag aaggacagtt atttgcattt aattcaccca tatgctttca aatctagtat     3240

atcttacttt ttggaaatgt tttatgctac aaattagtgc cttgtagcat gaacttaagt     3300

caaaacgtgt tatcaatata gagtgttgca gtgtatattg taacaaccta aaacgcagag     3360

aagtttaatt taatactgtt ttttttcttg aaggaatact cacatacatg gtttgaaatg     3420

tgcatagata tgcatgtcta tataattata aatgcatgtg tatatatatg caaatatatg     3480

tacatataca tgtatataca cacagacaca tgcatataca tgaatatacc ttgagcatga     3540

atccctggag aaatcgtttt cgtagctcac caatggtgag taaagataca gctcttttaa     3600

aggtcataag gataatatat tttccccatc aatgctgatt ctgagaaaag agcaatttat     3660

caaaattaaa cactgtaaaa gaaaggtgtc catatgtctt tacctaccta agtaaaacag     3720

gaagaaaatc agtaacatta tccttaggtt ttgacaatgg tacttgcttc ttgttgtttt     3780

attgtttcct gaattcatgc agatgcctgg ccattcctgg gaagagtgga taactcagaa     3840

gtcactgtac tccacagagc ctcactgcag tgtctaaagg tagatgcaaa ttaaaatgca     3900

gggaaaataa cttttctgat gttgatgcat gtctttggga aacacattta taaacatgga     3960

tacctgataa tagatattga aacccatttc ctgtgtgtta aaatatttaa aaagtggata     4020

ttccaggaat gttttgcagc tttgtacaag taacataaat tggacacctc agaatgaaag     4080

ttcatgttgg ttctgaatgg ttcactgcag ctcctgtcac aagctgggat ggatttatca     4140

cattgagtta tgaaattacc tggttctaag aatttttgag tggcaaaaat agaaaacaat     4200

cttcatttga aaacatccct aagcttgaat aaatggatac catagatagc ttctcttttt     4260

tattctggtg tcattaccag catctgaatt tcaagttctt aaaatttcaa aaattaaaat     4320

ttttcattat tagctatcca tttatctttt acatgaactt gtcatgaaca aattcaaatg     4380

tttatgccag caaatttttg tactgttgca tagttaaaaa tgctgggagt ctctgcatag     4440

atacaaaata ttattaaatt attacataaa tttaatttta taaaatttaa tcatgcttct     4500

tttgtctggg taatagacat tggacagata tttttagttc agatggtgat tctgaagctt     4560

acatctccct taaaaaaatc taaagcagct cttatgggct tctaatttta atataaataa     4620

ataatttaaa ttttattggt gttattggaa gaaaaatgct attaatgggc taataaaaaa     4680

catgtgtttc tcttatggat tttaataagc tccagtatta ttcaaatgat caaaaatata     4740

gttataattt tttgaatttt aaaaatgtga ttgctctaat aaagaataaa atctatgctt     4800

tttaacaaac atagttttgg tgcctaattc tgtaatatgt tttattgaaa ttagattcat     4860

ttctctaatg tgagaaaaat atatccagta atagtattga ctgtttaaaa aattgagctc     4920

atcaaaaata ttgtcatcaa atacaggtgg ttaatctgac atacattgca gttacatgca     4980

ttatttttat ttacaacatt tgctccttaa tgatgaattt atctgtgtta ccctgttttt     5040

ctacctggaa ctccatagaa tgatgtttgc aaaccaacat gtgctctttt cagtcattca     5100

ctgttttaat atgacatggt agagaagata aggtttatgg caggtaattt tttgtaatgt     5160

gtattaaacg aagttcaaag attagaaata catctgtgtc ctgaaaacct tagatacata     5220

gccgactgta tacagaggtt catctcaacc tcaacactat tgacttttgg ggctggatag     5280

ttctctgttg tgggggtttg tcttgtgcac tgtaggtttt tagtagcatc cacactttct     5340

cctcaccaga tgccagttgc accctccccc aagttgagac aaccaaaaat gtctccagat     5400

attgccagct accccttgag ggatggtacc tctggttgag aaccattgct agagaatgat     5460

ctttactgaa tttgcccttt ataagaaacc cagtgaattt ctagagcaag tcccaaaaac     5520

taagggacag ctaagaagtt attatggttg acttcaaagg cctaaactgt gttttttatg     5580

tccactaaac aacttgatta aaagacggaa ttttgactcg tgtctgtatc atacaagtac     5640

aaatactaat tttgccctat gtatccgtaa atgtcatttg tgattttgac ttatttattt     5700

aatgcccttt cttatgccgt gggttttcaa gtttactcat ttctatggtt gcaaataact     5760

ctaaaactta ttatataaac tttcatatta taggcagaac acaatggcta aatatctgtt     5820

gcatgtactt taaagtttat tataaaatat aaacagatat ataaagatgt tgactcttac     5880

ctgtgatttt gcatggtcag actcggtgtc aggtacggag aggattctca tgactgtctt     5940

acctctactg aatattctag tgagttatat gatttacgga gtgattaaca gaggtctata     6000

taaagttact tttccccttt acttaattat attgtagtgt gcagataaca aaactgctac     6060

cttctcatcc aagtggtctg tagaattcat gtcccttaca gtggtcattt aaagtcaata     6120

tttatttatg tatgtaataa aaaaagttgg atttttgtgt atgtctgtca cattatttag     6180

agagaagtaa tcttgtaaaa atgttttgta aaaaacaaaa aagtattgta aatagtcttg     6240

atattctgtg actcattatt ttcatgttag agtttgtaca tactggttca ataataaagt     6300

atccttaaac caga                                                       6314


<210>  772
<211>  2522
<212>  DNA
<213>  homo sapiens

<400>  772
accccaacgc cgcttctgcg gccaaagtag gttgggagtg gaaggtggtg gctgctgctc       60

cgcagtgtcg ggaagatggc gccgccggtg gcagagaggg ggctaaagag cgtcgtgtgg      120

cagaagataa aagcaacagt gtttgatgac tgcaagaaag aaggcgaatg gaagataatg      180

cttttagatg aatttaccac taagcttttg gcatcgtgtt gcaaaatgac agatcttcta      240

gaagaaggta ttactgttgt agagaatatt tataagaacc gtgaacctgt cagacaaatg      300

aaagctcttt atttcatcac tccgacatca aagtctgtag attgtttctt acatgatttt      360

gcaagtaaat cggagaacaa gtataaagca gcatatattt acttcactga cttttgccct      420

gataatctct ttaacaaaat taaggcttct tgctccaagt caataagaag atgtaaagaa      480

ataaatattt ccttcattcc acatgaatct caggtgtata ctcttgatgt accagatgca      540

ttctattact gttatagtcc agaccctggt aatgcaaagg gaaaagatgc cattatggaa      600

acaatggctg accagatagt tacagtgtgt gccaccttgg atgaaaatcc cggagtaaga      660

tataaaagta aacctctaga taatgccagt aagcttgcac agcttgttga aaaaaagctt      720

gaagactact acaagattga tgaaaagagc ctaataaagg gtaaaactca ttcacagctc      780

ttaataattg atcgtggctt tgatcctgtg tccactgtcc tgcatgaact gacctttcag      840

gcaatggcat atgatctact accaattgag aatgatacat acaaatataa aacagatgga      900

aaagaaaagg aggccatcct tgaagaagaa gatgacctct gggttagaat tcgacatcga      960

catattgcgg ttgtgttaga ggaaattccc aagcttatga aagaaatttc atcaacaaag     1020

aaagcaacag aaggaaagac atcacttagt gctcttaccc agctgatgaa aaagatgccc     1080

catttccgaa aacagattac taagcaagtt gtccatctta acttagcaga agattgcatg     1140

aataagttca agcttaatat agaaaagctc tgcaaaactg aacaggacct ggcacttgga     1200

actgatgcag aaggacagaa ggtgaaagat tccatgcgag tactccttcc agttctactc     1260

aacaaaaatc atgataattg tgataaaata agagcaattc tactttatat cttcagtatt     1320

aatggaacta cggaagaaaa tttggacagg ttgatccaga atgtaaagat agaaaatgag     1380

agtgacatga ttcgtaactg gagttacctt ggtgttccca ttgttcccca atctcaacaa     1440

ggcaaaccgt taagaaagga tcggtctgca gaagaaactt ttcagctctc tcggtggaca     1500

ccttttatca aagatattat ggaggatgct attgataata gattagattc aaaagaatgg     1560

ccatattgtt cccagtgtcc agcagtatgg aatggttcag gagctgtaag tgctcgccag     1620

aaacccagag ctaattattt agaagaccga aaaaatgggt caaagctgat tgtttttgta     1680

attggaggga tcacatactc tgaagtgcgt tgtgcttatg aagtttctca ggcacataaa     1740

tcctgtgaag ttattattgg ttctacacat gttttaacac ccaaaaagct gttggatgat     1800

ataaagatgc tgaataaacc caaggataaa gtctccttaa ttaaagatga atagcatttc     1860

tttttggagg gtttagagat tcttactaat atgttgaact aaaatagaaa gaaaatgttg     1920

ctgtcatgta atttaaacaa tgtaaatatt ttatggaata atggcttttc aaatacattt     1980

cttaaggaac tgtttatgat tattactgga tttgtcattt ttgataattt aaatattgct     2040

gctgctttgt agatgatgag aagaaatgtt aaagtgcttt ctaaaaggaa attttttcac     2100

ctttggagga gaatatatta gagttgtggg taatttttca cagccaccta tgtacatact     2160

aattacccat tggatactta tatctaaaag tctcatgctg aagtatagtt tttgggaaag     2220

aatgatttta aataaagaga ttgtaaaagt aaaaaactgt aaatgtatat gtatgataga     2280

attgtttcct ctaagtgtag tttttctttc aactaaaatt cagtttatgt gtaaaataat     2340

tcagtcatta atagaaatgg agtgatttca cagtgtgtac tgttttgcca catacttcta     2400

aagaacacaa ttttatataa ttttgaaatc atgtatgttt aaattagaaa accaaaaatc     2460

atgaacattc taagagaaaa taaatataga atttaaaaaa ttaaaaaaaa aaaaaaaaaa     2520

aa                                                                    2522


<210>  773
<211>  1054
<212>  DNA
<213>  homo sapiens

<400>  773
gcccccgcct ggagtccaga cccgacggcc ggcccagttc cacgcaccca gcgagcccaa       60

gcgccttctc cgcaccaggg aagccccacc caccagaagc caagatgtcc agcaagcggg      120

ccaaagccaa gaccaccaag aagcggccac agcgggccac atccaatgtc ttcgcaatgt      180

ttgaccagtc ccagatccag gagtttaagg aggctttcaa catgattgac cagaaccgtg      240

atggcttcat tgacaaggag gacctgcacg acatgctggc ctcgctgggt ttcatccatg      300

aggaccacct ccgggagctg ctcaccacca tgggtgaccg cttcacagat gaggaagtgg      360

acgagatgta ccgggaggca cccattgata agaaaggcaa cttcaactac gtggagttca      420

cccgcatcct caaacatggc gccaaggata aagacgacta ggccacccca gccccctgac      480

accccagccc ccgccagtca cccctccccg cacacacccg tccataccag ctccctgccc      540

atgaccctcg ctcagggatc cccctttgag gggttagggt cccagttccc agtggaagaa      600

acaggccagg agaagtgcgt gccgagctga ggcagatgtt cccacagtga ccccagagcc      660

ctgggctata gtctctgacc cctccaagga aagaccacct tctggggaca tgggctggag      720

ggcaggacct agaggcacca agggaaggcc ccattccggg gctgttcccc gaggaggaag      780

ggaaggggct ctgtgtgccc cccaggagga agaggccctg agtcctggga tcagacaccc      840

cttcacgtgt atccccacac aaatgcaagc tcaccaaggt cccctctcag tccccttccc      900

tacaccctga ccggccactg ccgcacaccc acccagagca cgccacccgc catgggagtg      960

tgctcaggag tcgcgggcag cgtggacatc tgtcccagag ggggcagaat ctccaataga     1020

ggactgagca ctgctaaaaa aaaaaaaaaa aaaa                                 1054


<210>  774
<211>  5056
<212>  DNA
<213>  homo sapiens

<400>  774
actcggctgg gagaatccgc gccagggaat ccagctctcc ggactcagct gcaaacaaaa       60

agcgccgggt cttgctccct cctcccgccc gccgacgcgc acccggagaa acagttttat      120

acagaaatgc aacaagtagt acccggggtc tgcagagcgc cccgcgccgc ctgacttggc      180

cgggcgaagc ccgcctgcag agacccgggc cggcctccgg acaaaggacg gaggaggggc      240

tggacggcgc tgcgaagtcc gaaagaggcc atttagcgac tctggccagg ctaaggggaa      300

tgcagaggag acacagagcc ggcgggccaa gaggacgatc cggccgctgc acgcagggcg      360

ggaggcgatg gaggctgccc gcgccttgcg cctcctgctc gtggtgtgcg gctgcctcgc      420

gctcccgccg ctggccgagc ccgtgtgccc ggagcgctgc gactgccagc atccccagca      480

tctcctgtgc accaacaggg ggctccgcgt agtgcccaag accagctcgc tgccgagccc      540

ccacgacgtg ctcacctaca gcctcggcgg caacttcata accaacatca cggccttcga      600

cttccaccgt ctggggcagc tcagacggct ggacctgcag tacaaccaga tccgctctct      660

gcaccccaag accttcgaga agctctcgcg gctggaagag ctgtacctgg ggaacaacct      720

cttgcaggcg ctcgccccgg gcacgctggc cccgctgcgc aagctgcgca tcctctacgc      780

caacgggaac gagatcagcc gcctaagccg cggctccttc gagggcctgg agagtctagt      840

caagctgcgg ctggacggga acgccctggg ggcgctgccg gacgcggtct tcgctccctt      900

gggcaacctg ctctacctac atctggagtc caaccggatc cgctttctgg gcaagaacgc      960

cttcgcccag ctaggcaagc tgcgcttcct caacctctct gccaacgagc tacagccctc     1020

cctgcgccac gcggccacct tcgcaccgct gcgctccctc tcctccctca tcctctcggc     1080

caacaacctg cagcacctcg ggccgcgcat cttccagcac ctgccacgtc tcggcctgct     1140

ctcgctcagg ggcaaccagc tcacgcacct cgcgcctgag gccttttggg gcttggaggc     1200

cctgcgcgag ctgcgcctgg agggtaatcg gctgagccag ctgccaactg cgctgctgga     1260

gcctctgcac agcctggagg cgctggacct gagcggcaat gagctgtccg ccctgcaccc     1320

ggccaccttc ggccacctgg gccggctgcg cgagctcagc ctgcgcaaca acgcgctcag     1380

cgccctatcc ggggacatct tcgccgccag cccagccctt tatcggctgg atctagacgg     1440

caacggctgg acctgcgact gccggctgcg aggcctgaag cgctggatgg gcgactggca     1500

ctcgcagggc cggctcctca ctgtcttcgt gcagtgtcgc caccccccgg ccctgcgagg     1560

caaatacctg gattacctgg atgaccagca gctgcaaaat ggatcctgcg cggatccctc     1620

gccctcagct tccctgaccg ctgaccgcag gcggcagccc ctacccacgg ccgcagggga     1680

ggagatgacg ccacctgcag gtctcgcgga ggagctgccg ccgcagccgc agctccagca     1740

gcaggggcga tttctagctg gggtggcctg ggatggggcc gccagggagc tggtaggcaa     1800

ccgcagcgcc ctaaggctga gtcggcgggg cccgggcctc cagcagccca gcccctccgt     1860

cgctgccgcc gcgggcccgg ctccacagtc cctagacctg cacaagaagc cccagcgggg     1920

ccgtccgact cgggcagatc ccgccctcgc ggagcccacc ccaacggcct ctcctggctc     1980

tgcgccatcg cccgccggcg acccctggca gcgcgcgacg aagcatcgtc tgggcacgga     2040

gcaccaggag cgtgccgccc agtccgacgg tggggccggg ctgccgccgc tggtgtccga     2100

cccatgcgac ttcaacaagt tcattctgtg caacctgacg gtggaggcgg tgggcgcaga     2160

cagcgcctcg gtgcgctggg ccgtgcgcga gcaccgcagt ccccggccgc tgggcggcgc     2220

gcgcttccgc ctgctctttg accgctttgg ccagcagccc aagttccacc gcttcgtcta     2280

cctgcctgag agcagcgact cggccacgct gcgcgagctg cgcggggaca ccccctacct     2340

ggtgtgcgtg gagggcgtgc ttgggggccg tgtctgccct gtggctcccc gggaccactg     2400

cgcggggctg gtcaccctac cggaggccgg gagccggggc ggcgtcgact accagctgct     2460

gaccttggcc ctgctgacgg tcaacgcgct gctggtgctc ctggccttgg cggcctgggc     2520

gtctcgctgg ctgcgtagga aactgcgggc taggcggaag ggcggggccc cggtccacgt     2580

tcggcacatg tactccaccc gacggcccct gcgctccatg ggcaccggcg tgtccgccga     2640

cttctcggga ttccagtcgc accggccacg caccaccgtg tgcgcgctca gtgaggcgga     2700

cctcatcgaa ttcccctgcg accgcttcat ggacagtgcg ggcggcggcg cgggcggcag     2760

cctgagacgg gaggaccgtc tcctgcagcg atttgccgac taggtccagg gcatatagag     2820

accatctcat tggccctaag gagccgcctc tccgtgaggc ccaccagccc acctcagggg     2880

aagtgccgtt ttgtgcactt gccagagagg ccggtgggga cagagggcca attcgggcac     2940

catcccccaa ttcccaatac tcgagaagta aatggatggt acttggtggt cagagccaga     3000

gtaggggaca aatggatggt gggatgctga ggtcggaggc ttcgcttgga ggctttgaca     3060

cagctatgcg aatggctttt gtagcactgc aatgcagaag ccaggctttg ggggtagaaa     3120

gggggtgctt gtgcccccaa catggccaga aatatttggg tgcatgcttt ttgtttgctc     3180

agtgtcaaac agagaagttt tgtttctatt taaggaagga acttattacc attacaaagg     3240

aggcttggcc agggactcca ctggtttggt gatctctgcc aagaaggggg atgtaaacag     3300

gtggtaaagt ttaacatacc cgccaaggaa ctcgtttatg ttggctgata gagcattcag     3360

gataccttaa agtttaataa gagacgcatt tttttttttc aaaaatgtga aaagctctga     3420

catttaacga actgaccaat agactcaagg actgttttag ttggactggg ccattttatt     3480

atgttccttt taatattaac agtacaagag cgcttgctga cttcgaggat aactaagatt     3540

acatactttc tcaggagaag gctgcatgca agacttctct gtcagggttg ctcctgtggc     3600

ttttttaatt ttattttttt aaacctatat atggaaaagg aaatttcaat gccagatttg     3660

ataaaagaat gtgatgtata tgtagctgat gacccactgg ggaacaccag tgttccagtt     3720

cacttaccac atctgtgaca gtgtgtttag attggaataa atgtgatgca ttacttctta     3780

tgtttttatc agtgacatgg ttgactgtgc cctaattctc ttgagttgca gttaagcaat     3840

gaaggttatt tcctaatagg gaagcaaaag gtgattgtca attgatagtt taatgtttga     3900

ccacattagt gtctttatat gaaatagtag aggggaagaa attatagaaa acaaatgtga     3960

aaaaaataca ccagtgggta tctgttctac taaaaccaga agattgttat gagtacttaa     4020

acctcactgt gaaataatga tatattttgc aattaatccc tccccaactg agtgtcttac     4080

tgtgttatta aatcttatct tttagttaat agttgcagta tttcttttaa atgtttttgt     4140

tttaaactta ggggtaggat cctttatttg ttcagttgtt tccaactatt tgggatactt     4200

tcattccctg ctatttatga agtacatgtt tatcactaag tgtagtggtt tggtttacat     4260

taataatttt atgtgtggtc taaaaatgca gtcactaaga gaatgtacac tgtggttatg     4320

gtcacagtgg ttatggattt attggcagtg gagtaccatg gaggtcactg caatggtgct     4380

aaggctgaca gtggaatctt ctgtttaggg ccttaagccc ctgagggtcc tggtgactca     4440

gggaatccat cacagccccg ggtctttcac cccagttcac tccttttatg tttggcctag     4500

attgacccat gcctgccctc ttctcaacag ctgagtaggg aaccagccat ctgaatgagc     4560

tgatcgttgt ttatgttcaa atgagtaaat gtccagacca cttaaaacta cagctgcttt     4620

tctggcagtc tcgtctgcgg ggccaaaact taataaacca caggaaatag actgtcattc     4680

ttagtttgct gccagggctt attttagatt gagagcatac tggtacatga gagcagtagt     4740

gttgtttgct cttattttca accagggagc tatctggcac cttttgtgct cctggctttt     4800

ttcaatcata gcactattgc atctcctagc tatttctttt gcccagcagg gtaatattga     4860

gtcccattgc aagtatggac aaggcctctg gttctcctca ccacccacct tttcagccat     4920

agaacatcac tgaaaatgcc taatgcctgg atctgtgttc tactttagtt tcactgggaa     4980

gtctttcagt gggagatgaa taaatgttat acattgttat gtccagttat gtcaataaac     5040

ccactaatag agataa                                                     5056


<210>  775
<211>  586
<212>  DNA
<213>  homo sapiens

<400>  775
agttaaaagg gtgggagcgt ccgggggccc atctctctcg ggtggagtct tctgacagct       60

ggtgcgcctg cccgggaaca tcctcctgga ctcaatcatg gcttgtggtc tggtcgccag      120

caacctgaat ctcaaacctg gagagtgcct tcgagtgcga ggcgaggtgg ctcctgacgc      180

taagagcttc gtgctgaacc tgggcaaaga cagcaacaac ctgtgcctgc acttcaaccc      240

tcgcttcaac gcccacggcg acgccaacac catcgtgtgc aacagcaagg acggcggggc      300

ctgggggacc gagcagcggg aggctgtctt tcccttccag cctggaagtg ttgcagaggt      360

gtgcatcacc ttcgaccagg ccaacctgac cgtcaagctg ccagatggat acgaattcaa      420

gttccccaac cgcctcaacc tggaggccat caactacatg gcagctgacg gtgacttcaa      480

gatcaaatgt gtggcctttg actgaaatca gccagcccat ggcccccaat aaaggcagct      540

gcctctgctc cctctgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                     586


<210>  776
<211>  1973
<212>  DNA
<213>  homo sapiens

<400>  776
gtgtgcaaat agaggaataa atagcagggc agcaactatg tctggaggtc attgtctttc       60

ctgtctcagt agtaatcaat cactgcttat cttcaaaaac ccagagtagg ggatggggca      120

gttagtgggg acagagggca gatgggtaag attcagagca caggctagtg tgacggaagt      180

ttaaacttgt gagttaaata gggtttggca atctagctgg atagcatccc tgccccttga      240

agagatgttt ttgtggcgcc acactactga cttaggcata atgcctagag atggattaga      300

actgcacaat gaactagtgg tgaggttcag tttaatggaa attggtgaaa gcttttagga      360

taaaatgata atctttgttt ctttcaggaa aatggcagac aatttttcgg taagtgtttt      420

atgcctgttt cttccccttg atcagctcca catggttgag ggttgggggt tttgttttta      480

ccatgacttt cccttttcac tctcccactg cgtggcttcc cctggactca tttgtccaat      540

gagggcttgc aagctggagc cttgtttttc cagcagcaga tttgggaaga aagccaggca      600

gagcgaggcc tgggactcac tcacagtaac cctttcacca aaaggcccag ggcggaaggg      660

agtggactct gccggcagga gctgagaaat cctctgagta gcgggaagtg cggtacagtc      720

tgggcattct gatgtttgtg attgtttttc tcacggtgat gaaaaagtat gtgctataag      780

tagaggagcg ctaactcctg acttgagcta attatgaaaa tgcagccctc cctgatctga      840

gacgttggga ggcaagaata aagtgaaaaa gtatatgtaa tcccaacatc taattttagt      900

cttagaaact caaactatta ataagtggaa aaagtttaat gatatgcatg taatgccttt      960

gccatattcc tctccttctt agatcacata ttcctatttt cctgaaaatt ctgcttttga     1020

gaatgctttc tgtcccgtaa ttgtgtatgt ctttctttcc agctccatga tgcgttatct     1080

gggtctggaa acccaaaccc tcaaggatgg cctggcgcat gggggaacca gcctgctggg     1140

gcagggggct acccaggggc ttcctatcct ggggcctacc ccgggcaggc acccccaggg     1200

gcttatcctg gacaggcacc tccaggcgcc taccctggag cacctggagc ttatcccgga     1260

gcacctgcac ctggagtcta cccagggcca cccagcggcc ctggggccta cccatcttct     1320

ggacagccaa gtgccaccgg agcctaccct gccactggcc cctatggcgc ccctgctggg     1380

ccactgattg tgccttataa cctgcctttg cctgggggag tggtgcctcg catgctgata     1440

acaattctgg gcacggtgaa gcccaatgca aacagaattg ctttagattt ccaaagaggg     1500

aatgatgttg ccttccactt taacccacgc ttcaatgaga acaacaggag agtcattgtt     1560

tgcaatacaa agctggataa taactgggga agggaagaaa gacagtcggt tttcccattt     1620

gaaagtggga aaccattcaa aatacaagta ctggttgaac ctgaccactt caaggttgca     1680

gtgaatgatg ctcacttgtt gcagtacaat catcgggtta aaaaactcaa tgaaatcagc     1740

aaactgggaa tttctggtga catagacctc accagtgctt catataccat gatataatct     1800

gaaaggggca gattaaaaaa aaaaaaagaa tctaaacctt acatgtgtaa aggtttcatg     1860

ttcactgtga gtgaaaattt ttacattcat caatatccct cttgtaagtc atctacttaa     1920

taaatattac agtgaattac ctgtctcaat atgtcaaaaa aaaaaaaaaa aaa            1973


<210>  777
<211>  9433
<212>  DNA
<213>  homo sapiens

<400>  777
ttccgaacat tcttagcatc gctcgcgccg cgccgcgccg cctgagccga gccgagcctc       60

tgctgccgcc gccgcggccc cgccgcccgc cgcgggcgcc caccaagcac tttgcagact      120

cgcttccacc ctgcgggcca ttccgcgcgg cggggcccgg gcccggggcg gccgcgtcca      180

ggcacaggcc atgcagtgac gcccccccac ccctccacct ttgcccggag cgcgggcagc      240

agcccagcgc gccagccggc cccggggcag gagcggtgct aggcaggggt ggggtggccg      300

ggcccaggga ccgggagccg gggagggagc cgggcaccga gcagagggcg ggggaagcgg      360

cgccgaagtt tgcctcggac tcgccgggcg ctgcggtggc tccctgggcc gaggactgtt      420

gctgccgctg ccgccgccgc ttcattgcac attcaagtgg aaaattttca ggagtcagca      480

gaaacattgt gtccaaaaaa gactgagtcg cagttaccac caaacccagg aggagactct      540

ccctggaaaa cttcccttcc ctttcggttt attttcttga aaaggctcca ggcttcggct      600

tggaaaatcc caccgccaaa attgagccca gcagctggag cggcagtgag agccctgccg      660

aaaacatgga aaggatgagt gactctgcag ataagccaat tgacaatgat gcagaagggg      720

tctggagccc cgacatcgag caaagctttc aggaggccct ggctatctat ccaccatgtg      780

ggaggaggaa aatcatctta tcagacgaag gcaaaatgta tggtaggaat gaattgatag      840

ccagatacat caaactcagg acaggcaaga cgaggaccag aaaacaggtg tctagtcaca      900

ttcaggttct tgccagaagg aaatctcgtg attttcattc caagctaaag gatcagactg      960

caaaggataa ggccctgcag cacatggcgg ccatgtcctc agcccagatc gtctcggcca     1020

ctgccattca taacaagctg gggctgcctg ggattccacg cccgaccttc ccaggggcgc     1080

cggggttctg gccgggaatg attcaaacag ggcagccagg atcctcacaa gacgtcaagc     1140

cttttgtgca gcaggcctac cccatccagc cagcggtcac agcccccatt ccagggtttg     1200

agcctgcatc ggccccagct ccctcagtcc ctgcctggca aggtcgctcc attggcacaa     1260

ccaagcttcg cctggtggaa ttttcagctt ttctcgagca gcagcgagac ccagactcgt     1320

acaacaaaca cctcttcgtg cacattgggc atgccaacca ttcttacagt gacccattgc     1380

ttgaatcagt ggacattcgt cagatttatg acaaatttcc tgaaaagaaa ggtggcttaa     1440

aggaactgtt tggaaagggc cctcaaaatg ccttcttcct cgtaaaattc tgggctgatt     1500

taaactgcaa tattcaagat gatgctgggg ctttttatgg tgtaaccagt cagtacgaga     1560

gttctgaaaa tatgacagtc acctgttcca ccaaagtttg ctcctttggg aagcaagtag     1620

tagaaaaagt agagacggag tatgcaaggt ttgagaatgg ccgatttgta taccgaataa     1680

accgctcccc aatgtgtgaa tatatgatca acttcatcca caagctcaaa cacttaccag     1740

agaaatatat gatgaacagt gttttggaaa acttcacaat tttattggtg gtaacaaaca     1800

gggatacaca agaaactcta ctctgcatgg cctgtgtgtt tgaagtttca aatagtgaac     1860

acggagcaca acatcatatt tacaggcttg taaaggactg aacatggtta tttatatata     1920

tagatatctg tatatacaca cacacatatg tgcacacaca cactctctct ccattatcga     1980

acgactgact gtaaacctca ccacacaggg tggtgccctg gccccgaggt caccccgact     2040

tttctaaatc ttgtttgagt gaagtcattt tttcatgtgt tcatactatc attgtagctg     2100

tgaagttctg gtacagttgt aaaaagagaa attgagttgt ttctctatgt tcttcagatg     2160

tgcagcccac aattcctcgg gaaaggtgaa cctgaacaac ccaagtctct ctctgcagag     2220

ccctgtttct aattgtggta gaaaatattg agacagagca tttgccatgg gacatttaca     2280

gcctttatac aaatgtattt agttctcttt tttccaacat aaaattcttg ttttaagata     2340

caagtaaaat taatctttaa atataaatgt aaattagtac acaaaactaa gaatctttag     2400

acttatcttt gtaactaatt agggtggaag ttatgaaaga atgtaattca ctaaattatt     2460

ttttaaatga aacctttttt tttctttttg aaaccaaatg ttaaactata gccttaagaa     2520

atgcttggta gaagtgtcct aatgagacaa atttgtactt ttatcctcaa ggttaacact     2580

aatctcctaa tccattaaac tcttgaacag gtattacaaa ggaagaaaac ttcacccctt     2640

atccttaaca tatatagtat atttaaaaaa tataaaattg tattgtacta atgtgatgat     2700

ggattattta atgaaaaaga aaaaatggct ctttttgcaa taagtagata catactgaaa     2760

aaatctaaac ttacaatgtt tatagtcttg tgtgtgcagt tatattttat atggacgacc     2820

aaatttttta ttaagatgag taaatatttg aaccactgaa ttttaataac aaaattttaa     2880

aattggcatg aatacggaat actgcactgt gagatgcaaa gtatacagaa tctgtggctg     2940

ggagaaaatt tcatcaaata gacaagtaaa aggctcatca gttttagcat ctctgctccc     3000

cagaaaattg taagcatcct caccagcctg tggatacatt ctttatttct agtgacccaa     3060

tatgcatatt aacctgctat aactagggct atatgtgtag gtatgtgtat acatatacac     3120

aaatgcacat atagagttaa cacatttagt gaacacttgt ttagtgtcac tcagtttgct     3180

aggtgctgat atgtacgtat atctcaatgt gtctgtagac ttagatacat cctcttgaag     3240

cacatccatt tctttagcgt ctctcagtaa gttacagtac ttgtttgact taggtttaag     3300

aggcccagct acctatctct gaccttttca aataggctca tttgggagat tcttttgcca     3360

ggagagattc aactttccaa tctaagtatt ccagagcatt gcccaggcag agttggtttg     3420

atgtggccag atgttttgag ttatttccct taagtgtttc actggggaga gaacagggag     3480

tgctcctcca gcttcccaaa gaaatatgtt tttgtaagtg gtaggaacat gtgcacacaa     3540

tagaacatga aataagtttt ttaacttgta aaacatgtca agatttttcc accaagctag     3600

aaaataaaaa acttagttct accacatcca attaacttac acaccccctt ccctgtctca     3660

acacctgctt tgaccctgct tttctattat tacatcagtc agcatcttgt ggtccctaac     3720

atgaggatgt ggctggctcg tgggaaacag caaaacacta agcctgacct ctcccaaatt     3780

gggaagacca gaggagaaag tgcaaaactg tccccatttg gaatgcccat tccttctaga     3840

aaccagttgg acagtgctcc tctgcccttc ataaacagac tactgttggg tccctgattc     3900

caggctggcc tgtgaaggat tgccccaggt gtcccctttc acggttgtca catttacagt     3960

gacttctgtt gaacacccct cttagggatg tttcttttgc tcttatttcc tgcatctttc     4020

cttaagggaa gccccatcct ctcccaggac caggagttta tgaccaggcg agcacaaatg     4080

gctaaaagcc aagctgtcct agaacttcag tgggagagct gtctggttca tattctaccc     4140

aggaatggta cttttcagtg cagccaggag ggctcttggg atttcctttc caaagcacaa     4200

aaatactggg acccaagaag aacagctaga ggacaactct gttggcacag agacggggac     4260

agcccagtct gctgacctca cagggtcagc tgggcccccc tggtgcttca ccacctgcat     4320

cctcttgctc agaatgcctt tgcagttgag ttttctgggt ttctatgatt gaccttgagg     4380

tttactcctt gctcttacaa catttctaag gatttttaaa agtttacttc ttgtcttgtt     4440

cttctaaagc tttctccagg acagatattt tccctgtctt aaccactggt ccagtcatcc     4500

cagtgggctt ctctttgtct ctcccagatt agacctttgg gtgagattgg catcacaaca     4560

tctaatctga gtctgtcttt tgtccttcat tctgtatggc agtctccctt tgttataaaa     4620

gctttctaaa gcatactaaa gaagccttcc cagagccccg tcttgcttct cttccaggtg     4680

ctctatcccc tcgagaccct ctggtgccag gcttgcttca cggccatctt gtgttgtcac     4740

tgcagagttt ggaggccagt tttccacagc ctaaacaggg aggagctgca gaatggggct     4800

ctggtctctg ggcattcatt tccctcatag aggctgagaa taaaacaagg acttattcac     4860

acatgttcta gaaccccaga atggcccaag ttacctgaga ccagggtttc tcaaccttga     4920

caccattgac attttggact gggtaattct ttgttctgca gagctgtcct ttgcactgta     4980

ggagatttac taatatccct ggcctctacc cagtagtacc actagcacct attccccacc     5040

cagcgtgtct ccagatattg tcaaatatcc catcgggtgc aaaatgatcc ctggtcaaga     5100

tctgttgccc aagatgttac aggtcacaat gaccacattt gaaattgttt tccctttcat     5160

tttaccctgt gaaagcatct ctcctagagc cttgcaagag gcaggtgaca ttgtgtccat     5220

atttcttcct gtttcagaac ttctgtttca caacaatttc tctctcgcta caagtattct     5280

ttcactcagc actggggaag ttgggaacag ctggtcacca tcatcccttt aatcaactca     5340

cacctgttta aagagtgttt ctgatttgac cttcatccct tagtttactg gcgttaaaaa     5400

aagtctcagc aattttcatt atttctcgtg ggtctcatta tcaaaccttt acttatttcg     5460

gcatatttcc tctgggcttc ttctagtttc tgccttacaa gcaatgctgt tctgtaaatt     5520

tattgaaacc tctggaacat ttcaccttta gagatggagg atggaaggat tggtaccaga     5580

agagggctaa gatacgtttt ctgtcttgag ctgaaagcac agtctactct ccttcgtttt     5640

gtcgatgaga aagttgaggc cagaggggag gtgacatgtt tagagtcacc cagctggtta     5700

gtgacagaaa aagcgtgaga gttgtctagg attcctgcca ctttggtccc tggcctctcc     5760

tgggggaggc tgctgttctt aggtgctcta agcttaatcc ctcagaatgt gtggacaggt     5820

cagcttagaa gagatgggga gattcaggat ccccctgtgc cagagcacag cctcaccgga     5880

tgctgcttcc cacactgaag tgtcctgtcc gaccattgct atctgaggca tccacaagca     5940

ggtaggaaag ctggcgagcc attttacttc ctgaggacaa ttccccagcc acaggctctg     6000

agtcaaattt ctatttggta agcatcctag cagcaaagtc ctgcactcag accagccaaa     6060

aaacagcccc cattccaagt acttggtgtc aaaagtcccc gaacgacttt taaacccaag     6120

tcttcttaag gtttcagtac tgtggtggct ttagcagttg tttttgtgca actataaatt     6180

atttaaatca tctgagatga cagtcaattt tacaaaccag gtacatatta atttgtataa     6240

ttttgtatat gctctggtac actacctgaa ctaacgaagg gtagaactaa ttctgtttgt     6300

cagtgttcac acctgtaaca ttaggaggat atgtctgcat tgcttatttc tttatgttgg     6360

tgtttctgtg gcaaagccct gcacatggca tttctgaaaa gccttaaatc tttaagatgt     6420

tgcatgtagg gtatgcagtg caaaaggctg cctcagaact gtgagccctt ttgtaagctg     6480

gaagcatttc tcttactact gttacttttg taggaagttt tcaattcaga gctgccaaag     6540

tgttcccgta agcagtgcct tagtaatacc ttagtcatgc cgccagcctt ttcttacacc     6600

aattcctaat gttcatttac gaattggccc aatattggaa acaaaacaag caaaaattgt     6660

cttcattttt gttttgtaag cccatttttt ctccagttct ataggaaact gactgcttgg     6720

tgtaaaatcc gaaactggac acaagtcagt tctttcacca cactcaaatg tatataccaa     6780

aacaaaaggt tgcaacttca tagtttacta tgaaaagcaa attgtacttt ttaatgttgc     6840

cttttaaatt catgaccaaa tacttagcta tttgtgaatc ttctgcactc tagcatgaaa     6900

gtgcctttgg tttgagattc cagcttagaa aagtgctgcc ataataacga taatttgtag     6960

agagaccaaa aatattttga gatcaccgta atgcctttgg tttaccggga tgagtaacca     7020

accacaggcc tctgttcaca agagcacgac gtggtccccg cctgctgcta gtctgtctgc     7080

cactgggggc ctcccaacat ccatagcaca cttcagcgga aggaccccag aaactgttgt     7140

gtttgtgtgt gctgatgacc tagtgtgtca tttcacctcg tcacccagcc ctgcgtccgg     7200

atgaggggac ttctgcacaa atgacagaat ctcggctggt ggacagatac tacagctttc     7260

tcctcctcct tgtgttcgtg ttcagtctct gtggagactt tcttttccat tcaaatgaca     7320

gtgcgcactt atctggttta cacaatgata ccattttgaa agttggaagc ctcaaactga     7380

gacgacagtg cagaacaaaa caaaagtgag ttagggtcgt taaaattgaa gtgttcttct     7440

tagggcaaac atgttgactc cgagtattgt gtatgaatgt gctacgagaa acttccaaag     7500

agcaccattc acaatttggc attttcaaag aatgttccag ccctcaaagg ggcaactctt     7560

taaagtcctt gttggctttt atccaaacct tgtagaaatt gggaaagctg atagaggtaa     7620

ggaagacgag tgaaaaggac aagaaggcca aacaccagcc aaaaagaaac taggaaaaaa     7680

agattttctt tgctaatata gatgtaaaaa taacatcaga catctttgaa aattagcctc     7740

taaactctta atacatacgt tctgtgtgtc tctacctggc gtctttaaga atatcctctc     7800

tgggctctga aattttagga gtgattctta tccactccaa gttgtaagta tttgtagaaa     7860

tttgtgcaaa caaacaaaaa ctatcaaatg aaaagaaaat gtactcaacc taacttatag     7920

ttagcagctg gaattctcaa ctcttccctg ccagcactat accacagtgt ggaagaaatt     7980

agtcaaatgc ttgttttcct gcttctcttt tcaactgtta ctgtgctttg tttgaaagta     8040

gttttctctc tcaaagccgt tgcttatatc gttaagaatg aaggtttgtg tttaaaattt     8100

attgcattgc aaagggtagt ttcactgaag tcatgcacca ttaaataaga tgaaatattt     8160

gtatttattg tcctacttcc taagccgtaa cttcttttcc tctgtgaatt tgcattgagt     8220

cactcatgct acactacatc gctttagtat ttgagatggc atttatgttt cctctcgttt     8280

atcatgaaat ggggtcagat tccatcagat tccacctctg tcaggtggac tcttgtctgc     8340

cttccatgat gagatttttt ttctccttcc cctttcttta agagaggctg acagatctag     8400

gtgtcaatca attggaaacc agtctctgat tttttttcat tagttatttt ctatcattag     8460

tttcactgtg taaattagat atcaactgca cttctttaaa aaaaaataca tctccctatt     8520

acctccttga aagatttact tctgtaggcc tttttcaata ggctcatgac tgcagacaag     8580

gaaaaaaaaa gtaaaaacaa aaacagtatg tgcctgaaaa tgacaaaaaa aaaatttgta     8640

acatttaaaa aagaaacctg aatagccttt aattctttaa taatacactt aaattttatg     8700

taaatcggtt ttcgccacgt gtgtttgttc acattctaaa tgacttaatg ggattctcac     8760

ggtctgtgtc tttgtgtcac gtgtataaaa tgggcttgtg atgtaagcgt ttcatctggt     8820

cagtggttcc tttgatattg tactgctgct gggagtgggc tgtggaacct gccttcgggt     8880

aactgggttc ctcttgggta gattggagag atgggggtgg gcgtgggcaa attctcacac     8940

atgttttctt aacctatttg cagaaacttt caaaaggcat ttgattaaac ctcttggcag     9000

tacagtattc ttgtatttgt taacgtctgt gtttaggtac tggtaccttt ttgttttaaa     9060

atgttctaag tgttggcttt aaagtgaatt tatctttagt atgatagtta tatgaaaatt     9120

ataggatttg tgtgcagaga atttttttat aaagtgcttt gtaaaaaaaa aaaaatgtat     9180

tctagctttt gcggtacata tgtgtgataa ctttaatacc catgacagtt aagtgcaatt     9240

atttcatcac tctaaaaatg ctatttttgt gtcagttcct gcaggtgttt tcatgtcttt     9300

gcaaagtgac acattttgat gccttcttga taaagtggta gacattttgt agctttctag     9360

aaactttgta ttcatacggt atcaatgaaa aataaagaaa atgaaagtgt gggtcaaaaa     9420

aaaaaaaaaa aaa                                                        9433


<210>  778
<211>  9433
<212>  DNA
<213>  homo sapiens

<400>  778
ttccgaacat tcttagcatc gctcgcgccg cgccgcgccg cctgagccga gccgagcctc       60

tgctgccgcc gccgcggccc cgccgcccgc cgcgggcgcc caccaagcac tttgcagact      120

cgcttccacc ctgcgggcca ttccgcgcgg cggggcccgg gcccggggcg gccgcgtcca      180

ggcacaggcc atgcagtgac gcccccccac ccctccacct ttgcccggag cgcgggcagc      240

agcccagcgc gccagccggc cccggggcag gagcggtgct aggcaggggt ggggtggccg      300

ggcccaggga ccgggagccg gggagggagc cgggcaccga gcagagggcg ggggaagcgg      360

cgccgaagtt tgcctcggac tcgccgggcg ctgcggtggc tccctgggcc gaggactgtt      420

gctgccgctg ccgccgccgc ttcattgcac attcaagtgg aaaattttca ggagtcagca      480

gaaacattgt gtccaaaaaa gactgagtcg cagttaccac caaacccagg aggagactct      540

ccctggaaaa cttcccttcc ctttcggttt attttcttga aaaggctcca ggcttcggct      600

tggaaaatcc caccgccaaa attgagccca gcagctggag cggcagtgag agccctgccg      660

aaaacatgga aaggatgagt gactctgcag ataagccaat tgacaatgat gcagaagggg      720

tctggagccc cgacatcgag caaagctttc aggaggccct ggctatctat ccaccatgtg      780

ggaggaggaa aatcatctta tcagacgaag gcaaaatgta tggtaggaat gaattgatag      840

ccagatacat caaactcagg acaggcaaga cgaggaccag aaaacaggtg tctagtcaca      900

ttcaggttct tgccagaagg aaatctcgtg attttcattc caagctaaag gatcagactg      960

caaaggataa ggccctgcag cacatggcgg ccatgtcctc agcccagatc gtctcggcca     1020

ctgccattca taacaagctg gggctgcctg ggattccacg cccgaccttc ccaggggcgc     1080

cggggttctg gccgggaatg attcaaacag ggcagccagg atcctcacaa gacgtcaagc     1140

cttttgtgca gcaggcctac cccatccagc cagcggtcac agcccccatt ccagggtttg     1200

agcctgcatc ggccccagct ccctcagtcc ctgcctggca aggtcgctcc attggcacaa     1260

ccaagcttcg cctggtggaa ttttcagctt ttctcgagca gcagcgagac ccagactcgt     1320

acaacaaaca cctcttcgtg cacattgggc atgccaacca ttcttacagt gacccattgc     1380

ttgaatcagt ggacattcgt cagatttatg acaaatttcc tgaaaagaaa ggtggcttaa     1440

aggaactgtt tggaaagggc cctcaaaatg ccttcttcct cgtaaaattc tgggctgatt     1500

taaactgcaa tattcaagat gatgctgggg ctttttatgg tgtaaccagt cagtacgaga     1560

gttctgaaaa tatgacagtc acctgttcca ccaaagtttg ctcctttggg aagcaagtag     1620

tagaaaaagt agagacggag tatgcaaggt ttgagaatgg ccgatttgta taccgaataa     1680

accgctcccc aatgtgtgaa tatatgatca acttcatcca caagctcaaa cacttaccag     1740

agaaatatat gatgaacagt gttttggaaa acttcacaat tttattggtg gtaacaaaca     1800

gggatacaca agaaactcta ctctgcatgg cctgtgtgtt tgaagtttca aatagtgaac     1860

acggagcaca acatcatatt tacaggcttg taaaggactg aacatggtta tttatatata     1920

tagatatctg tatatacaca cacacatatg tgcacacaca cactctctct ccattatcga     1980

acgactgact gtaaacctca ccacacaggg tggtgccctg gccccgaggt caccccgact     2040

tttctaaatc ttgtttgagt gaagtcattt tttcatgtgt tcatactatc attgtagctg     2100

tgaagttctg gtacagttgt aaaaagagaa attgagttgt ttctctatgt tcttcagatg     2160

tgcagcccac aattcctcgg gaaaggtgaa cctgaacaac ccaagtctct ctctgcagag     2220

ccctgtttct aattgtggta gaaaatattg agacagagca tttgccatgg gacatttaca     2280

gcctttatac aaatgtattt agttctcttt tttccaacat aaaattcttg ttttaagata     2340

caagtaaaat taatctttaa atataaatgt aaattagtac acaaaactaa gaatctttag     2400

acttatcttt gtaactaatt agggtggaag ttatgaaaga atgtaattca ctaaattatt     2460

ttttaaatga aacctttttt tttctttttg aaaccaaatg ttaaactata gccttaagaa     2520

atgcttggta gaagtgtcct aatgagacaa atttgtactt ttatcctcaa ggttaacact     2580

aatctcctaa tccattaaac tcttgaacag gtattacaaa ggaagaaaac ttcacccctt     2640

atccttaaca tatatagtat atttaaaaaa tataaaattg tattgtacta atgtgatgat     2700

ggattattta atgaaaaaga aaaaatggct ctttttgcaa taagtagata catactgaaa     2760

aaatctaaac ttacaatgtt tatagtcttg tgtgtgcagt tatattttat atggacgacc     2820

aaatttttta ttaagatgag taaatatttg aaccactgaa ttttaataac aaaattttaa     2880

aattggcatg aatacggaat actgcactgt gagatgcaaa gtatacagaa tctgtggctg     2940

ggagaaaatt tcatcaaata gacaagtaaa aggctcatca gttttagcat ctctgctccc     3000

cagaaaattg taagcatcct caccagcctg tggatacatt ctttatttct agtgacccaa     3060

tatgcatatt aacctgctat aactagggct atatgtgtag gtatgtgtat acatatacac     3120

aaatgcacat atagagttaa cacatttagt gaacacttgt ttagtgtcac tcagtttgct     3180

aggtgctgat atgtacgtat atctcaatgt gtctgtagac ttagatacat cctcttgaag     3240

cacatccatt tctttagcgt ctctcagtaa gttacagtac ttgtttgact taggtttaag     3300

aggcccagct acctatctct gaccttttca aataggctca tttgggagat tcttttgcca     3360

ggagagattc aactttccaa tctaagtatt ccagagcatt gcccaggcag agttggtttg     3420

atgtggccag atgttttgag ttatttccct taagtgtttc actggggaga gaacagggag     3480

tgctcctcca gcttcccaaa gaaatatgtt tttgtaagtg gtaggaacat gtgcacacaa     3540

tagaacatga aataagtttt ttaacttgta aaacatgtca agatttttcc accaagctag     3600

aaaataaaaa acttagttct accacatcca attaacttac acaccccctt ccctgtctca     3660

acacctgctt tgaccctgct tttctattat tacatcagtc agcatcttgt ggtccctaac     3720

atgaggatgt ggctggctcg tgggaaacag caaaacacta agcctgacct ctcccaaatt     3780

gggaagacca gaggagaaag tgcaaaactg tccccatttg gaatgcccat tccttctaga     3840

aaccagttgg acagtgctcc tctgcccttc ataaacagac tactgttggg tccctgattc     3900

caggctggcc tgtgaaggat tgccccaggt gtcccctttc acggttgtca catttacagt     3960

gacttctgtt gaacacccct cttagggatg tttcttttgc tcttatttcc tgcatctttc     4020

cttaagggaa gccccatcct ctcccaggac caggagttta tgaccaggcg agcacaaatg     4080

gctaaaagcc aagctgtcct agaacttcag tgggagagct gtctggttca tattctaccc     4140

aggaatggta cttttcagtg cagccaggag ggctcttggg atttcctttc caaagcacaa     4200

aaatactggg acccaagaag aacagctaga ggacaactct gttggcacag agacggggac     4260

agcccagtct gctgacctca cagggtcagc tgggcccccc tggtgcttca ccacctgcat     4320

cctcttgctc agaatgcctt tgcagttgag ttttctgggt ttctatgatt gaccttgagg     4380

tttactcctt gctcttacaa catttctaag gatttttaaa agtttacttc ttgtcttgtt     4440

cttctaaagc tttctccagg acagatattt tccctgtctt aaccactggt ccagtcatcc     4500

cagtgggctt ctctttgtct ctcccagatt agacctttgg gtgagattgg catcacaaca     4560

tctaatctga gtctgtcttt tgtccttcat tctgtatggc agtctccctt tgttataaaa     4620

gctttctaaa gcatactaaa gaagccttcc cagagccccg tcttgcttct cttccaggtg     4680

ctctatcccc tcgagaccct ctggtgccag gcttgcttca cggccatctt gtgttgtcac     4740

tgcagagttt ggaggccagt tttccacagc ctaaacaggg aggagctgca gaatggggct     4800

ctggtctctg ggcattcatt tccctcatag aggctgagaa taaaacaagg acttattcac     4860

acatgttcta gaaccccaga atggcccaag ttacctgaga ccagggtttc tcaaccttga     4920

caccattgac attttggact gggtaattct ttgttctgca gagctgtcct ttgcactgta     4980

ggagatttac taatatccct ggcctctacc cagtagtacc actagcacct attccccacc     5040

cagcgtgtct ccagatattg tcaaatatcc catcgggtgc aaaatgatcc ctggtcaaga     5100

tctgttgccc aagatgttac aggtcacaat gaccacattt gaaattgttt tccctttcat     5160

tttaccctgt gaaagcatct ctcctagagc cttgcaagag gcaggtgaca ttgtgtccat     5220

atttcttcct gtttcagaac ttctgtttca caacaatttc tctctcgcta caagtattct     5280

ttcactcagc actggggaag ttgggaacag ctggtcacca tcatcccttt aatcaactca     5340

cacctgttta aagagtgttt ctgatttgac cttcatccct tagtttactg gcgttaaaaa     5400

aagtctcagc aattttcatt atttctcgtg ggtctcatta tcaaaccttt acttatttcg     5460

gcatatttcc tctgggcttc ttctagtttc tgccttacaa gcaatgctgt tctgtaaatt     5520

tattgaaacc tctggaacat ttcaccttta gagatggagg atggaaggat tggtaccaga     5580

agagggctaa gatacgtttt ctgtcttgag ctgaaagcac agtctactct ccttcgtttt     5640

gtcgatgaga aagttgaggc cagaggggag gtgacatgtt tagagtcacc cagctggtta     5700

gtgacagaaa aagcgtgaga gttgtctagg attcctgcca ctttggtccc tggcctctcc     5760

tgggggaggc tgctgttctt aggtgctcta agcttaatcc ctcagaatgt gtggacaggt     5820

cagcttagaa gagatgggga gattcaggat ccccctgtgc cagagcacag cctcaccgga     5880

tgctgcttcc cacactgaag tgtcctgtcc gaccattgct atctgaggca tccacaagca     5940

ggtaggaaag ctggcgagcc attttacttc ctgaggacaa ttccccagcc acaggctctg     6000

agtcaaattt ctatttggta agcatcctag cagcaaagtc ctgcactcag accagccaaa     6060

aaacagcccc cattccaagt acttggtgtc aaaagtcccc gaacgacttt taaacccaag     6120

tcttcttaag gtttcagtac tgtggtggct ttagcagttg tttttgtgca actataaatt     6180

atttaaatca tctgagatga cagtcaattt tacaaaccag gtacatatta atttgtataa     6240

ttttgtatat gctctggtac actacctgaa ctaacgaagg gtagaactaa ttctgtttgt     6300

cagtgttcac acctgtaaca ttaggaggat atgtctgcat tgcttatttc tttatgttgg     6360

tgtttctgtg gcaaagccct gcacatggca tttctgaaaa gccttaaatc tttaagatgt     6420

tgcatgtagg gtatgcagtg caaaaggctg cctcagaact gtgagccctt ttgtaagctg     6480

gaagcatttc tcttactact gttacttttg taggaagttt tcaattcaga gctgccaaag     6540

tgttcccgta agcagtgcct tagtaatacc ttagtcatgc cgccagcctt ttcttacacc     6600

aattcctaat gttcatttac gaattggccc aatattggaa acaaaacaag caaaaattgt     6660

cttcattttt gttttgtaag cccatttttt ctccagttct ataggaaact gactgcttgg     6720

tgtaaaatcc gaaactggac acaagtcagt tctttcacca cactcaaatg tatataccaa     6780

aacaaaaggt tgcaacttca tagtttacta tgaaaagcaa attgtacttt ttaatgttgc     6840

cttttaaatt catgaccaaa tacttagcta tttgtgaatc ttctgcactc tagcatgaaa     6900

gtgcctttgg tttgagattc cagcttagaa aagtgctgcc ataataacga taatttgtag     6960

agagaccaaa aatattttga gatcaccgta atgcctttgg tttaccggga tgagtaacca     7020

accacaggcc tctgttcaca agagcacgac gtggtccccg cctgctgcta gtctgtctgc     7080

cactgggggc ctcccaacat ccatagcaca cttcagcgga aggaccccag aaactgttgt     7140

gtttgtgtgt gctgatgacc tagtgtgtca tttcacctcg tcacccagcc ctgcgtccgg     7200

atgaggggac ttctgcacaa atgacagaat ctcggctggt ggacagatac tacagctttc     7260

tcctcctcct tgtgttcgtg ttcagtctct gtggagactt tcttttccat tcaaatgaca     7320

gtgcgcactt atctggttta cacaatgata ccattttgaa agttggaagc ctcaaactga     7380

gacgacagtg cagaacaaaa caaaagtgag ttagggtcgt taaaattgaa gtgttcttct     7440

tagggcaaac atgttgactc cgagtattgt gtatgaatgt gctacgagaa acttccaaag     7500

agcaccattc acaatttggc attttcaaag aatgttccag ccctcaaagg ggcaactctt     7560

taaagtcctt gttggctttt atccaaacct tgtagaaatt gggaaagctg atagaggtaa     7620

ggaagacgag tgaaaaggac aagaaggcca aacaccagcc aaaaagaaac taggaaaaaa     7680

agattttctt tgctaatata gatgtaaaaa taacatcaga catctttgaa aattagcctc     7740

taaactctta atacatacgt tctgtgtgtc tctacctggc gtctttaaga atatcctctc     7800

tgggctctga aattttagga gtgattctta tccactccaa gttgtaagta tttgtagaaa     7860

tttgtgcaaa caaacaaaaa ctatcaaatg aaaagaaaat gtactcaacc taacttatag     7920

ttagcagctg gaattctcaa ctcttccctg ccagcactat accacagtgt ggaagaaatt     7980

agtcaaatgc ttgttttcct gcttctcttt tcaactgtta ctgtgctttg tttgaaagta     8040

gttttctctc tcaaagccgt tgcttatatc gttaagaatg aaggtttgtg tttaaaattt     8100

attgcattgc aaagggtagt ttcactgaag tcatgcacca ttaaataaga tgaaatattt     8160

gtatttattg tcctacttcc taagccgtaa cttcttttcc tctgtgaatt tgcattgagt     8220

cactcatgct acactacatc gctttagtat ttgagatggc atttatgttt cctctcgttt     8280

atcatgaaat ggggtcagat tccatcagat tccacctctg tcaggtggac tcttgtctgc     8340

cttccatgat gagatttttt ttctccttcc cctttcttta agagaggctg acagatctag     8400

gtgtcaatca attggaaacc agtctctgat tttttttcat tagttatttt ctatcattag     8460

tttcactgtg taaattagat atcaactgca cttctttaaa aaaaaataca tctccctatt     8520

acctccttga aagatttact tctgtaggcc tttttcaata ggctcatgac tgcagacaag     8580

gaaaaaaaaa gtaaaaacaa aaacagtatg tgcctgaaaa tgacaaaaaa aaaatttgta     8640

acatttaaaa aagaaacctg aatagccttt aattctttaa taatacactt aaattttatg     8700

taaatcggtt ttcgccacgt gtgtttgttc acattctaaa tgacttaatg ggattctcac     8760

ggtctgtgtc tttgtgtcac gtgtataaaa tgggcttgtg atgtaagcgt ttcatctggt     8820

cagtggttcc tttgatattg tactgctgct gggagtgggc tgtggaacct gccttcgggt     8880

aactgggttc ctcttgggta gattggagag atgggggtgg gcgtgggcaa attctcacac     8940

atgttttctt aacctatttg cagaaacttt caaaaggcat ttgattaaac ctcttggcag     9000

tacagtattc ttgtatttgt taacgtctgt gtttaggtac tggtaccttt ttgttttaaa     9060

atgttctaag tgttggcttt aaagtgaatt tatctttagt atgatagtta tatgaaaatt     9120

ataggatttg tgtgcagaga atttttttat aaagtgcttt gtaaaaaaaa aaaaatgtat     9180

tctagctttt gcggtacata tgtgtgataa ctttaatacc catgacagtt aagtgcaatt     9240

atttcatcac tctaaaaatg ctatttttgt gtcagttcct gcaggtgttt tcatgtcttt     9300

gcaaagtgac acattttgat gccttcttga taaagtggta gacattttgt agctttctag     9360

aaactttgta ttcatacggt atcaatgaaa aataaagaaa atgaaagtgt gggtcaaaaa     9420

aaaaaaaaaa aaa                                                        9433


<210>  779
<211>  3409
<212>  DNA
<213>  homo sapiens

<400>  779
taagaaacga cacacagatt aggcagtgct actcttctta aatctctcat ttgtttccta       60

ggttccctgg ttgtgaaaat acatgagata aatcatgaag gccactatca tcctccttct      120

gcttgcacaa gtttcctggg ctggaccgtt tcaacagaga ggcttatttg actttatgct      180

agaagatgag gcttctggga taggcccaga agttcctgat gaccgcgact tcgagccctc      240

cctaggccca gtgtgcccct tccgctgtca atgccatctt cgagtggtcc agtgttctga      300

tttgggtctg gacaaagtgc caaaggatct tccccctgac acaactctgc tagacctgca      360

aaacaacaaa ataaccgaaa tcaaagatgg agactttaag aacctgaaga accttcacgt      420

tgtctacctt cataacaaca atatctctgt agttggatca agtgacttct gcccacctgg      480

acacaacacc aaaaaggctt cttattcggg tgtgagtctt ttcagcaacc cggtccagta      540

ctgggagata cagccatcca ccttcagatg tgtctacgtg cgctctgcca ttcaactcgg      600

aaactataag taattctcaa gaaagccctc atttttataa cctggcaaaa tcttgttaat      660

gtcattgcta aaaaataaat aaaagctaga tactggaaac ctaactgcaa tgtggatgtt      720

ttacccacat gacttattat gcataaagcc aaatttccag tttaagtaat tgcctacaat      780

aaaaagaaat tttgcctgcc attttcagaa tcatcttttg aagctttctg ttgatgttaa      840

ctgagctact agagatattc ttatttcact aaatgtaaaa tttggagtaa atatatatgt      900

caatatttag taaagctttt cttttttaat ttccaggaaa aaataaaaag agtatgagtc      960

ttctgtaatt cattgagcag ttagctcatt tgagataaag tcaaatgcca aacactagct     1020

ctgtattaat ccccatcatt actggtaaag cctcatttga atgtgtgaat tcaatacagg     1080

ctatgtaaaa tttttactaa tgtcattatt ttgaaaaaat aaatttaaaa atacattcaa     1140

aattactatt gtatacaagc ttaattgtta atattcccta aacacaattt tatgaaggga     1200

gaagacattg gtttgttgac aataacagta catcttttca agttctcagc tatttcttct     1260

acctctccct atcttacatt tgagtatggt aacttatgtc atctatgttg aatgtaagct     1320

tataaagcac aaagcataca tttcctgact ggtctagaga actgatgttt caatttaccc     1380

ctctgctaaa taaatattaa aactatcatg tgacttcatg taatcaggct gaacatttct     1440

acaattacta gatgtattag acgtaagtat tttctttagt taaaccaccc atgttagaaa     1500

tgttttctgt agaatttata aacaactatc aatgcagaca atttaataag cctggggatg     1560

atttacttac agtaaacatt tatcaaattg tacatttgtg ctatcaacaa ttaataagca     1620

aatatgtgaa aatagtttct gtcttctatg aagttagata tttgatggtt aaaaccccta     1680

taaatcatag tttcatatgg gaaaaaataa ttgaaataca gtgtaaattt aaataattta     1740

ttaagtatag caaataattg aaatatggtg gactaaattt tgtcatagaa atatgtgcaa     1800

gttatagtag tggctcacat gagaggtaat caattctgct aatagtagca gaatgagtgc     1860

agtggaacat gaaaaacttg aggagataac agttgaggtg ggtttccata gatgcataat     1920

agttcaagag caagatttgg tggggaggca ctattcaaga cagggactaa gttcaaaatc     1980

caagacgtat gctgggacac acctctgaca ggttggcata aaggaggctt aatcaaacta     2040

tttttcttct tctgaaacag aagcaataat tttcatttac atttgacata tcccgaggta     2100

atattaacat tagggaaagt tactcttttc catctttcca cattcttgca ggaccataaa     2160

atctgaattt tccagtattt ttaataagag ggaagaaacc tctctttttc ttctcttttt     2220

catctcccaa gagatcctcc tctcatgact acagttgaat aggtggtttc tattggaaga     2280

cattcaggaa ttcaaggtgc atgtccataa atggactttt tttgttgttg ttcagagctg     2340

gaccttgaat gatgcatcct tctctctgtt gtaaccatga ataatgcacc cttcatgcta     2400

tagcctttaa cgattcaccc ttcttattgt aaccttgaat gattcaccct ttatggtgta     2460

gccttgagtg acgcaccctt catgttgtag ccttcaatga tgcacactcc atgttatagc     2520

cttgaatgat atacccttta tgctgcagcc tttctcttat ggggaaaagc ctgcagatat     2580

cctgctgctt aactgacaag tgtggtgaga aataagtaga aatctaaaga ggggaagacc     2640

attttggaca cttatctgca aggcagatcc aacacacttt tccagtagtc aagctacttc     2700

taattttgtt cagtatcaaa atgagaaaca ggcctgattc tccagcactc ttgtcaacac     2760

aacttccccc catatttata tatatacaca cacatatata tctttatata tatacacaca     2820

tatatatctt tatatatata tatttatata tatatctttt tgcatatata catatatatg     2880

tatctttatt tcctttgaaa taaagataaa tatagctgat ttctttggct tcgacactta     2940

ctatttgcat gactaaggga agctagttaa cctttctgtg actcatttcc ttgtccataa     3000

aatgggaata ttaattgtac atgtcttatg gattggtgtg tgaattcagt tagcgagtgt     3060

agaatataac ttatagatca aagtagagta aatggaaagg gctcaactat ggtgttgcta     3120

ctgccattgt tattacaggc acacagttcg agctataatc atttcaaggg aaattcttat     3180

gtgtcagttc tggatcgagg tctgagattc tgcatttcaa acaaacttcc aggaatgctg     3240

ctgcttcttg gtccacactt ggagaaataa gtcagcagag agtcctctcg tttcctattg     3300

taccatgtct gtcttttgtc tcctgcttat tggcctctgt aaggaactca cagctgctat     3360

aataaagtac caaaaactgg gtggcttaaa acaaaaaaaa aaaaaaaaa                 3409


<210>  780
<211>  3366
<212>  DNA
<213>  homo sapiens

<400>  780
gttccattcc cgggggattg gagtagcgtt ggagtcaccg acgccatccc ctcccgcctc       60

tggcgtgcat ggagcatgcg cttccttcct cacttcctct gcaggaggga gcgagagtaa      120

agctacgccc tggcgcgcag tctccgcgtc acaggaactt cagcacccac agggcggaca      180

gcgctcccct ctacctggag acttgactcc cgcgcgcccc aaccctgctt atcccttgac      240

cgtcgagtgt cagagatcct gcagccgccc agtcccggcc cctctcccgc cccacaccca      300

ccctcctggc tcttcctgtt tttactcctc cttttcattc ataacaaaag ctacagctcc      360

aggagcccag cgccgggctg tgacccaagc cgagcgtgga agaatggggt tcctcgggac      420

cggcacttgg attctggtgt tagtgctccc gattcaagct ttccccaaac ctggaggaag      480

ccaagacaaa tctctacata atagagaatt aagtgcagaa agacctttga atgaacagat      540

tgctgaagca gaagaagaca agattaaaaa aacatatcct ccagaaaaca agccaggtca      600

gagcaactat tcttttgttg ataacttgaa cctgctaaag gcaataacag aaaaggaaaa      660

aattgagaaa gaaagacaat ctataagaag ctccccactt gataataagt tgaatgtgga      720

agatgttgat tcaaccaaga atcgaaaact gatcgatgat tatgactcta ctaagagtgg      780

attggatcat aaatttcaag atgatccaga tggtcttcat caactagacg ggactccttt      840

aaccgctgaa gacattgtcc ataaaatcgc tgccaggatt tatgaagaaa atgacagagc      900

cgtgtttgac aagattgttt ctaaactact taatctcggc cttatcacag aaagccaagc      960

acatacactg gaagatgaag tagcagaggt tttacaaaaa ttaatctcaa aggaagccaa     1020

caattatgag gaggatccca ataagcccac aagctggact gagaatcagg ctggaaaaat     1080

accagagaaa gtgactccaa tggcagcaat tcaagatggt cttgctaagg gagaaaacga     1140

tgaaacagta tctaacacat taaccttgac aaatggcttg gaaaggagaa ctaaaaccta     1200

cagtgaagac aactttgagg aactccaata tttcccaaat ttctatgcgc tactgaaaag     1260

tattgattca gaaaaagaag caaaagagaa agaaacactg attactatca tgaaaacact     1320

gattgacttt gtgaagatga tggtgaaata tggaacaata tctccagaag aaggtgtttc     1380

ctaccttgaa aacttggatg aaatgattgc tcttcagacc aaaaacaagc tagaaaaaaa     1440

tgctactgac aatataagca agcttttccc agcaccatca gagaagagtc atgaagaaac     1500

agacagtacc aaggaagaag cagctaagat ggaaaaggaa tatggaagct tgaaggattc     1560

cacaaaagat gataactcca acccaggagg aaagacagat gaacccaaag gaaaaacaga     1620

agcctatttg gaagccatca gaaaaaatat tgaatggttg aagaaacatg acaaaaaggg     1680

aaataaagaa gattatgacc tttcaaagat gagagacttc atcaataaac aagctgatgc     1740

ttatgtggag aaaggcatcc ttgacaagga agaagccgag gccatcaagc gcatttatag     1800

cagcctgtaa aaatggcaaa agatccagga gtctttcaac tgtttcagaa aacataatat     1860

agcttaaaac acttctaatt ctgtgattaa aattttttga cccaagggtt attagaaagt     1920

gctgaattta cagtagttaa ccttttacaa gtggttaaaa catagctttc ttcccgtaaa     1980

aactatctga aagtaaagtt gtatgtaagc tgagattttg tatacagaat ccttatttcc     2040

tcatagactt atattttata atcagaatat gttgctttga aaaagcctct aatggactga     2100

ccttaaaact catccttctt ccactgtctc atccacataa gcactccccg aagaattaag     2160

ggggttctgt tttcaaggca tgccaagtac taaagcacct tgcagagcgt gtctattaca     2220

agatgtcatt tccaccagca gttcccttag gggagctgaa ataaattcac attttctcaa     2280

agtctcatag ctttggagga gccatctgct tttttggctg ctctttttag ctggcttttt     2340

attaggctca gtgacataaa aaggatccag gtaaatgggt ataggatttg ctggatttac     2400

taacaatttc cccctgttct taacacttcc tattagtgac ttttcagaca ttgagtttac     2460

ttataaagag agatatttat gtactctcta agaagacaaa tgaggtcata aacactgcat     2520

aaagcaaggc aaaaatgtat gccacatctc agttatctaa actagattag atccaagcca     2580

agttttctca acagagagca aagggccagg cagtaaggta gaaatagaga taaaaatcat     2640

tccttccttg tgatccaaag ctggtcgagc agctttcctg gaggaaaagg ttaatgaact     2700

tcaggtccct gcaactcagc ccccaccaca aacacagccc tggaaacata cagtggcgca     2760

aggtcctctt gaaatgttaa tggttaatgt tcccaaacca gagaatgctt tgaaaatgta     2820

tcattcagtg taaattaatt acatacatat ttttctatat atttgtttca aactgtaaaa     2880

ataacataat atgtaatttg tgtattagtg agaggtgaag ccagctggac ttcctgggtc     2940

gagtggggcc ttggagaact tttctgtctt acaagaggat tgtaaaatgc acccatcagt     3000

gctctgtaaa acacaccaat cagcgctctg tagctagcaa taggtttgta aaatgcaccc     3060

atcagcactc tgtaaaacgc accaatcagc actctgtaaa atgcaccaat cagcaggatt     3120

ctaaaagtag acaatcacag ggaggattga aaaaaagggc actctgatag ggcaaaaacg     3180

gaacatggga ggggacaaat aagggaataa aatctggcca ccccagccag cagcagcaac     3240

ctgttcaggt cgcctgccgc tgtggaagct ttgtcctttt gctcttcata ataaaccttg     3300

ctactgttca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaa                                                                3366


<210>  781
<211>  962
<212>  DNA
<213>  homo sapiens

<400>  781
gggaaagaat gcggagccgg gttcacacac cccgcggcgg cgaggcctta aatagggaaa       60

cggcctgagg cgcgcgcggg cctggagccg ggatccgccc taggggctcg gatcgccgcg      120

cgctcgccgc tcgcccgcca gcccgcccgt ggtccgtggc ggcgcgctcc acccggcacg      180

gggaggcgcg gggcgcacca tggccgcaga cacgccgggg aaaccgagcg cctcgccgat      240

ggcaggagcg ccggccagcg ccagccggac cccagacaag ccccggagcg cggccgagca      300

ccgcaagtcc tccaagccgg tcatggagaa gcggcgccga gcgcgtatta acgagagcct      360

cgctcagctc aaaaccctca tcctggacgc cctcagaaaa gagagctccc gccactcgaa      420

gctggagaag gcggacatcc tggagatgac cgtgagacac ctgcggagcc tgcgtcgcgt      480

gcaggtgacg gccgcgctca gcgccgaccc cgccgttctg ggcaagtacc gcgccggctt      540

ccacgagtgt ctggcggagg tgaaccgctt cctggccggc tgcgagggcg tcccggccga      600

cgtgcgctcc cgcctgctgg gccacctggc agcctgcctg cgccagctgg gaccctcccg      660

ccgcccggcc tcgctgtccc cggctgcccc cgcagaggcc ccagcgcccg aggtctacgc      720

gggccgcccg ctgctgccat cgctcggcgg ccccttccct ctgctcgcgc cgccgctgct      780

gccgggtctg acccgggcgc tgcccgccgc ccccagggcg gggccgcagg gcccgggtgg      840

gccctggagg ccgtggctgc gctgaggctg tggccctgag actgcatcgg aggcggcgcc      900

ccgttctagg gccgtggcct ttgccgagac tgtagcagag aaaacgtatt tattattcca      960

ga                                                                     962


<210>  782
<211>  1053
<212>  DNA
<213>  homo sapiens

<400>  782
gggaaagaat gcggagccgg gttcacacac cccgcggcgg cgaggcctta aatagggaaa       60

cggcctgagg cgcgcgcggg cctggagccg ggatccgccc taggggctcg gatcgccgcg      120

cgctcgccgc tcgcccgcca gcccgcccgt ggtccgtggc ggcgcgctcc acccggcacg      180

gggaggcgcg gggcgcacca tggccgcaga cacgccgggg aaaccgagcg cctcgccgat      240

ggcaggagcg ccggccagcg ccagccggac cccagacaag ccccggagcg cggccgagca      300

ccgcaaggtg gggtcccggc cgggcgtgag gggggcgacc ggggggcggg agggacgcgg      360

gactcagccg gtgcccgacc cgcagtcctc caagccggtc atggagaagc ggcgccgagc      420

gcgtattaac gagagcctcg ctcagctcaa aaccctcatc ctggacgccc tcagaaaaga      480

gagctcccgc cactcgaagc tggagaaggc ggacatcctg gagatgaccg tgagacacct      540

gcggagcctg cgtcgcgtgc aggtgacggc cgcgctcagc gccgaccccg ccgttctggg      600

caagtaccgc gccggcttcc acgagtgtct ggcggaggtg aaccgcttcc tggccggctg      660

cgagggcgtc ccggccgacg tgcgctcccg cctgctgggc cacctggcag cctgcctgcg      720

ccagctggga ccctcccgcc gcccggcctc gctgtccccg gctgcccccg cagaggcccc      780

agcgcccgag gtctacgcgg gccgcccgct gctgccatcg ctcggcggcc ccttccctct      840

gctcgcgccg ccgctgctgc cgggtctgac ccgggcgctg cccgccgccc ccagggcggg      900

gccgcagggc ccgggtgggc cctggaggcc gtggctgcgc tgaggctgtg gccctgagac      960

tgcatcggag gcggcgcccc gttctagggc cgtggccttt gccgagactg tagcagagaa     1020

aacgtattta ttattccaaa aaaaaaaaaa aaa                                  1053


<210>  783
<211>  962
<212>  DNA
<213>  homo sapiens

<400>  783
gggaaagaat gcggagccgg gttcacacac cccgcggcgg cgaggcctta aatagggaaa       60

cggcctgagg cgcgcgcggg cctggagccg ggatccgccc taggggctcg gatcgccgcg      120

cgctcgccgc tcgcccgcca gcccgcccgt ggtccgtggc ggcgcgctcc acccggcacg      180

gggaggcgcg gggcgcacca tggccgcaga cacgccgggg aaaccgagcg cctcgccgat      240

ggcaggagcg ccggccagcg ccagccggac cccagacaag ccccggagcg cggccgagca      300

ccgcaagtcc tccaagccgg tcatggagaa gcggcgccga gcgcgtatta acgagagcct      360

cgctcagctc aaaaccctca tcctggacgc cctcagaaaa gagagctccc gccactcgaa      420

gctggagaag gcggacatcc tggagatgac cgtgagacac ctgcggagcc tgcgtcgcgt      480

gcaggtgacg gccgcgctca gcgccgaccc cgccgttctg ggcaagtacc gcgccggctt      540

ccacgagtgt ctggcggagg tgaaccgctt cctggccggc tgcgagggcg tcccggccga      600

cgtgcgctcc cgcctgctgg gccacctggc agcctgcctg cgccagctgg gaccctcccg      660

ccgcccggcc tcgctgtccc cggctgcccc cgcagaggcc ccagcgcccg aggtctacgc      720

gggccgcccg ctgctgccat cgctcggcgg ccccttccct ctgctcgcgc cgccgctgct      780

gccgggtctg acccgggcgc tgcccgccgc ccccagggcg gggccgcagg gcccgggtgg      840

gccctggagg ccgtggctgc gctgaggctg tggccctgag actgcatcgg aggcggcgcc      900

ccgttctagg gccgtggcct ttgccgagac tgtagcagag aaaacgtatt tattattcca      960

ga                                                                     962


<210>  784
<211>  4604
<212>  DNA
<213>  homo sapiens

<400>  784
gctcttcttc cttccttctc cagtcccttc cactgtgcgt cttctgtccc ccgttcttcc       60

ccagcggacc cctctttcga gactccctag tggggtcccc agctcccggg cgatcctgcc      120

cttgccgagc gcgttttctg gagtcacctg ggggagggga gtcctgggca gggccgggct      180

ggggaagacg cctggggcac tgcccggcgt taacaaaggg agccgatacc gaccggcgtg      240

ggcgcggagc gggcggccgc caccgagcgt gctgagcaac cgcagcctcc gcggccgaga      300

gtgcagcgag caaggggaga gccagttgcg cagagccctg caaccagcag tccagggaga      360

agtggtgaat gtcatggagc ccagctgaaa tggactggcc cccttgagcc tgtcccaagc      420

cctggtgcca ggtgtccatc cccgtgctga gatgagtttt gatcatcctg agaaaaatgg      480

gccttggcct gcagacccaa taaaccttcc ctcccatgga taatagtgct aattcctgag      540

gacctgaagg gcctgccgcc cctgggggat tagccagaag caggcttgtt ttcctgctca      600

gaacaaagtg acttccctga acacatcttc attatgattc acaccaacct gaagaaaaag      660

ttcagctgct gcgtcctggt ctttcttctg tttgcagtca tctgtgtgtg gaaggaaaag      720

aagaaaggga gttactatga ttcctttaaa ttgcaaacca aggaattcca ggtgttaaag      780

agtctgggga aattggccat ggggtctgat tcccagtctg tatcctcaag cagcacccag      840

gacccccaca ggggccgcca gaccctcggc agtctcagag gcctagccaa ggccaaacca      900

gaggcctcct tccaggtgtg gaacaaggac agctcttcca aaaaccttat ccctaggctg      960

caaaagatct ggaagaatta cctaagcatg aacaagtaca aagtgtccta caaggggcca     1020

ggaccaggca tcaagttcag tgcagaggcc ctgcgctgcc acctccggga ccatgtgaat     1080

gtatccatgg tagaggtcac agattttccc ttcaatacct ctgaatggga gggttatctg     1140

cccaaggaga gcattaggac caaggctggg ccttggggca ggtgtgctgt tgtgtcgtca     1200

gcgggatctc tgaagtcctc ccaactaggc agagaaatcg atgatcatga cgcagtcctg     1260

aggtttaatg gggcacccac agccaacttc caacaagatg tgggcacaaa aactaccatt     1320

cgcctgatga actctcagtt ggttaccaca gagaagcgct tcctcaaaga cagtttgtac     1380

aatgaaggaa tcctaattgt atgggaccca tctgtatacc actcagatat cccaaagtgg     1440

taccagaatc cggattataa tttctttaac aactacaaga cttatcgtaa gctgcacccc     1500

aatcagccct tttacatcct caagccccag atgccttggg agctatggga cattcttcaa     1560

gaaatctccc cagaagagat tcagccaaac cccccatcct ctgggatgct tggtatcatc     1620

atcatgatga cgctgtgtga ccaggtggat atttatgagt tcctcccatc caagcgcaag     1680

actgacgtgt gctactacta ccagaagttc ttcgatagtg cctgcacgat gggtgcctac     1740

cacccgctgc tctatgagaa gaatttggtg aagcatctca accagggcac agatgaggac     1800

atctacctgc ttggaaaagc cacactgcct ggcttccgga ccattcactg ctaagcacag     1860

gctcctcact cttctccatc aggcattaaa tgaatggtct cttggccacc ccagcctggg     1920

aagaacattt tcctgaacaa ttccagcctg ctccttttac tctaggggcc tctgtcagca     1980

agaccatggg gacttcaaga gcctgtggtc aggaaatcag gtccagcctt ccctgtagcc     2040

agacagttta tgagcccaga gcctcctgcc acacacatgc acacatatct agcattcttt     2100

ccagacagca tcctccccgc cttccacctt ggtagatgca aggtctatct ctcccatcag     2160

ggctgccaaa gctgggcttt gtttttccca gcagaatgat gccattctca caaaccaatg     2220

ctctatattg cttgaagtct gcatctaaat attgatttca cgttttaaag aaattctctt     2280

aaattacaat tgtgcccaat gcagggtggc tctggggggc aagtaggtgg tacaggggat     2340

tggaaacatg ctccgcgcct ccagagaaaa gttgctcccg aggtccatgc ccctggaacg     2400

tgttcctatc actctggctg gttgggctgg tccttagact gggtgcttat gattaaaggg     2460

tcttggttag cccactttcc ctctccatgt ggagatggaa ggtagagaag gatacagtgt     2520

ctatcctcaa gttgctacgg ttcagtgaga gaggcagaca tctgaacagg caggtaggat     2580

tcagtgtgct cagtgcactg gggatttgga gagagatggg cttgctctct ctgtgcaccc     2640

aggagggcca cgcacttaaa actgtgtttg tggatcagag aaggctttat agcacagggg     2700

gcattcagat gagtcttaga ggaagagaag aaacatggca agcagattac atctgagccg     2760

tttgaattgt gtttttcttt cttcccatgt ttattttcta agatctacct gaacttagag     2820

actcaagata tttttttagg aaacctccta cccatgtctg aggtagcaag tgcagcctca     2880

cgacagatac caggcaatcc agagccacaa aacgtgattc ctccaggctc tgcctggcct     2940

gaccctgtcc tgtcagctgg gtttacatac cagtcccatt cttccttttc aatacctacc     3000

cccaaatctt ctcctaacca ccatctgttt ttttttttta aagcattttt tgctttaaaa     3060

gcatcctgac cccaatttct ttgagctcac gggccttttg ctgaaggtct ctcagggtgt     3120

agtggtgtgg ctctctggac ttaacgtcac tctcagaggt cagaaccttg gagatcagaa     3180

ctgattctca ccaggtgtga gaggtgtggt agcagattgc aatgctctgc acctcttcct     3240

tgcaagtgag caacttcagg ctctctgggc agaggctggc ccactgtagt ttgcagacat     3300

gctctccaga tggttttact aagtcccctc tccctgatag ggaatcctgc tggaccagcg     3360

cagccctggt gtggagaggt taaaagactt gcacaggatc accaagtcat gctgtagagc     3420

caggattcct agacccaggg ctctgcactc tcaaggctgg ccccatgtgc tcaaggggat     3480

ctaatgtttg ggctccaaac taaccatctc ggagctgggc tcctcattta ctgccaaacc     3540

ctcagcttat gtagctagaa agggccctgg agtgagaaag cctggatttt caaattgatg     3600

ctcccctact gactagctgt gccactctgg gcaaatgctc ttccttgagc ctgtttccac     3660

acctgtaaag tggggatgat gatcctatct cactgctttt gtgaggatta caggaaagca     3720

cctgtcctgg ctctgtacct ggcacgtagt aggtgctcag ttcatgctgg tttccttcct     3780

gcctttagta gggacctgct ctgtgctcac acctcggctg catgcaccct gctgtgacgg     3840

aggctagtgt ggaagaggtc ctgtcctcag ggaattaact gtcttattgg gagacaacaa     3900

ctgtcctcct tggaacaccc aagaaaccat gcaaagcagt ggacaacaca gaacacgccc     3960

tcctcctcgc tgcctgcagc tccaatctga ttctgcttgg gaatgggcgg agcacgtggg     4020

ctgcttaact gctgtatagg acaagcccct tacccctctc tgggcccatg aattcctggc     4080

ttggtttatg ttctgatttg acacactgat tttaatcttc gaatcatgac actgagtgca     4140

gaggaggtgg cattccgaca gcaggacata catgttggtg tgaagactgg gacgacactg     4200

ggtagaatct agtttttaat tattattaat ataaaggatc aaattaattt aaatatgatt     4260

ctgaagtcta cagaactttt agttctgtgc tgtctatgtg gacactttgg taaaatgcaa     4320

attatgatat ggacgttatc attggtctgg tgagatgttt catatttgtg acagttaatt     4380

taaaaattat gagttaatgc tgcctgtgtc tatggggttc tgtcttcttt gatagccatc     4440

tattcatctg gatcatggga ccctctctaa tccttccacc aatcaaataa gctattgcta     4500

ttggtttgga gttgagatat cagtctcgga aacttctgaa aaatgctaat aattacccaa     4560

ggattatgtc aaattttaaa ataaatgtgt gtgtgtttct ttaa                      4604


<210>  785
<211>  6732
<212>  DNA
<213>  homo sapiens

<400>  785
agcattcaaa ccttgcagag ctttgctctc agagagtttg taaaaagaca cactcctctt       60

acaagagttc atgctaccac atagcaaaga accttaaatt tttggaagaa caatatattc      120

attttggcat tgtgcagagc aaagtaaact cggtggcctc ttcttctcca cccctcaaaa      180

tgatagcaat ctctgccgtc agcagtgcac tcctgttctc ccttctctgt gaagcaagta      240

ccgtcgtcct actcaattcc actgactcat ccccgccaac caataatttc actgatattg      300

aagcagctct gaaagcacaa ttagattcag cggatatccc caaagccagg cggaagcgct      360

acatttcgca gaatgacatg atcgccattc ttgattatca taatcaagtt cggggcaaag      420

tgttcccacc ggcagcaaat atggaatata tggtttggga tgaaaatctt gcaaaatcgg      480

cagaggcttg ggcggctact tgcatttggg accatggacc ttcttactta ctgagatttt      540

tgggccaaaa tctatctgta cgcactggaa gatatcgctc tattctccag ttggtcaagc      600

catggtatga tgaagtgaaa gattatgctt ttccatatcc ccaggattgc aaccccagat      660

gtcctatgag atgttttggt cccatgtgca cacattatac gcagatggtt tgggccactt      720

ccaatcggat aggatgcgca attcatactt gccaaaacat gaatgtttgg ggatctgtgt      780

ggcgacgtgc agtttacttg gtatgcaact atgccccaaa gggcaattgg attggagaag      840

caccatataa agtaggggta ccatgttcat cttgtcctcc aagttatggg ggatcttgta      900

ctgacaatct gtgttttcca ggagttacgt caaactacct gtactggttt aaataagttt      960

accttttcct ccaggaaata taatgatttc tgggaacatg ggcatgtata tatatatatg     1020

gagagagaat tttgcacata ttatacatat tttgtgctaa tcttgttttc ctcttagtat     1080

tcctttgtat aaattagtgt ttgtctagca tgtttgttta atcctttgaa atatttgaaa     1140

catcaatttc tattttctga cctctaagcc taaattaaga tattgtatat gtaatgatga     1200

catagttgat gcatccaatc ctaaaactta cattccaaag gaattatatc attatgttcc     1260

taaggagtaa atatatattt gacctgtaag tgtgtgtatg tatacatata catatgtatg     1320

tgtatggatt tatatatgca cacaaacata taatatgtga tgtaacatgt agatgataat     1380

atgattcagt agtcaacttg agggaaattt ttaaaaaact attctcaatt atatacgagg     1440

tgatgggact tcttaacaca catttctata atacccatga aatgataatt tgtaaaataa     1500

cacttagtga tatctggaaa taataattca attaagcaac cacgaatttc accctggaga     1560

tattttttct tatttgagtc caccaaagga taatgccaac ttatataagt tctcaaatca     1620

tgccttccgc ttagtctcat tttattcatt cagtcgtcat gagttgagtg cttactacat     1680

gcaaggcact ctgctagtta tattctaata atgcagagat aattagacat ggttcccgcc     1740

ctcaagaagc tcacaaaagt attcaggaaa taatgcagac tagtgatttt gctataaaat     1800

tatttttgaa ggaagcagac acagcagtat ttacctgtag gtggagcaag taataagcca     1860

tgctgtgcaa tatatacata aagcttctgc ttctcatggg aatttagtta cagtgcttgg     1920

aatgagaagg ggaaggaaag aattaacaaa tgccaagatt tctggagcag attgtacagc     1980

tgtgactttg gaaaacagaa agtaagaccc tcagaaaacc aatgaagtct aagagaaata     2040

aaatttagtg gacaggtatg aaaagtgtaa ttgcgcctaa ctaccagatg gagagcttca     2100

gaatgggcta tccttagagt ctagtacatc ttgaggcctc tcagcaggag acaaaggatt     2160

ccaaaaagag atgtggaggt gctgagggca cctctatctc tttgttgttt agtctgtcat     2220

tgaatcaatc tacttatcat cttgggtctt tgagtattgt atgaaagatc cttcgtgcac     2280

accacacaca gtcatgattt tgttaaagta gccttcttca gatgcttttc taagggctag     2340

ttaccaactt tatttctgtg tttctgtaga agaaacattt tcagttcttc attgagtttg     2400

attatggaaa tccattcaaa gtcactatga aaattttact catgtagttt ggaaatgcaa     2460

cattttccta tcatgaaatc tctttcagag aggagaatac aacatcttag tccagacatt     2520

taacatactg catttcaagt acatgtgtgt gtgttttatt caggttgtgt aatgctcccg     2580

tagaattata gaacaattaa atatggttag ttccagagtg caaattacag aaggaagcta     2640

cttgtttaaa attccataca cgtttgcagt ttcttgtaca catttggata ctttgaaaga     2700

tgacagattg ttaaatccat tcaatggtaa agaaactcac catctggaga ttgagtctac     2760

ttgttaatga atgactagcc caattatcct tataaattga atatggtgac caaatgcttt     2820

gatatcatac tactctgcct ttgtgggcac atatgtagac actactaaaa ataaatattt     2880

ttggagatta aaatggagaa tagaagtaat tacattattt aggtcttaat ccaacttttt     2940

tctaatatat ctaaacaatt gaaagggaag cttattcatg gaatattggc ttgatttatc     3000

tagaaagttt ttccttcttc aattttacta tattcattct acaggaacag caataagtac     3060

tattaaacag aagatggcta cactaagttc caattttgtt gctgaattgc ttctgtgagt     3120

tcacttttca gttctaagga agaataatat ttgctacata tttcacaggg gttcttatga     3180

aggtaaattt accagattaa taaaaattta tgaatattaa aattatcatt aataatataa     3240

aacacttatt tgagattaaa ttaaattttt catgagcccc tctttggcag gaactctgtt     3300

taattctttg tatttatccc agcttcttaa atggtggctg taacataata aatgtttaat     3360

aaatgcttat atgaatggat ttttagaatt aactaagaag ccaaaaatgg caacaattta     3420

cagaaatccc acctttccat gcttaagaca aaaatgtctt aaatataaag ctgtgattat     3480

atcaaaaatc cagataaatc atcaaatata tcagattaag accagggttt acacacttag     3540

gcaatagtcc tttccaaacc atgacaaaaa ctacaagttt atttataatt taacaactca     3600

gctgaaaata taacgggtat atttgttatt ctaactctat tttttaaagt taataatata     3660

aagtggccat gtaaaatatt ttattttcca ggctaaagca aatgaaagtt tgctggtatc     3720

aacacagcct gccatatttt tcacagcatg caacaatggt gctaggatag ctatttctta     3780

ctgtaattgc cagaggcaga aatggtctgg gtataagcta tttcataaaa gcagctttaa     3840

attgtcagta ttaaggtttt catgtggaaa ggtgtcattc aaaaaaaaag taattggcat     3900

acatattcca catcatcgat cctctctgtg gtgttaattt ttttatatga ccagtagaaa     3960

aattttaata ttctcacaat ataggttttg gggcttccat atcatcaaaa gactgaaaaa     4020

ttataatttt agaattaaac tgatggattt cattatagaa ttatctgtga gttgtgtaga     4080

cacagtctta atgtttctgg ttatgacaga taagtttgct caaaaaatgt ggatgaagcc     4140

attattgtta ttattgttat tgcttctgtt cagttgtcta agtatcatcc cttctgtggc     4200

ccatcacgca gcagagttgc cctacaaatt tcatttggca gcgccataac attcatttaa     4260

aaagtttatg aaaacattca tttgaaagtt ccatgcagct ttagcacaga gttgaccaaa     4320

cactggcgta agttcaattt acacagaata tttgaattga aacaatagaa atttttctca     4380

taatatatac ctatgtgaaa ccaacttatc tgcataatta aatctaatac atatttaagc     4440

cagtttaagt gctttgtgtt gatgccatgc ttatcaaata catgcacaag ctaaacataa     4500

tttgaatggg tctatgaagg aaaaataatg cttagacttt ggtgtaggtt cttcctgtgt     4560

agccatatac ccaggctctg cagtatcgaa ggatgcaaat gttgacatag atggaagctc     4620

ttacctacca aagtgtttag gaaggataaa gttacatttg tcttaatttc taacattatc     4680

tttgctttta tgtttcataa aaatttgtca ttatttatgc tggtgaaacg tataatcaca     4740

tccaattatt tgaacacatg caaaataatt ttttaaatta tgttattgtt taaatttgac     4800

ttatgggaga tcagtcaaaa acttagaagg tttaacactt cactgattaa tggtgctgaa     4860

aacacgttac aattaccaca tatccttgct ataagttttg aagtttctta gcaattaaag     4920

tttttttatt cagtgtgaac tgtcagtatc tattctggtg ctaaatgtat ggtgctaaat     4980

gaattgttag tgttgatggc tttagtaatg ctccttttat tcattgctaa atttagtgtt     5040

atccatttga ttcctgattc agaaatatca ataaaatcct atgttaaatt aatctttacc     5100

aaaaacaggc aagttaactc tgttgtttta attcaacagt ccaacattat ttaggtgtta     5160

cagagtgtaa atatatttct ttgggagtta ttttcttttt aaaatctttt tatagcttgg     5220

caatgtccaa agtcaaatat cacctaaact ggttagatta cttctacagc taataatatt     5280

gcaggcactg gcgccctctg gtggttatga agacaaattc ttaatggcta cttgacctac     5340

agcaaaagcc atttctgtac cataaaaatt tgttgtgcaa tattagaatt atcatatgtt     5400

tcctacatct gacagcacct aaaatgtttg ataatattaa catgtatcta agaggaaaaa     5460

agagttaata tattctggca cccactttcc tagtaatgtt ttccatgatt ttccagttct     5520

gaggcactta ttaaagtgct tttttttttc tgaattaatt aggtattggt aaaatatatt     5580

tttaaattta gttagcttta taaacacaat tagaattaca attaattaac agaggtataa     5640

ttgtctcact ttcagaagtg atcatttatt tttatttagc acaggtcata agaaaaatat     5700

atagaaaaat aatcaatttc atatataaaa ggattatttc tccaccttta attattggcc     5760

tatcatttgt tagtgttatt tggtcatatt attgaactaa tgtattattc cattcaaagt     5820

ctttctagat ttaaaaatgt atgcaaaagc ttaggattat atcatgtgta actattatag     5880

ataacatcct aaaccttcag tttagatata taattgactg ggtgtaatct cttttgtaat     5940

ctgttttgac agatttctta aattatgtta gcataatcaa ggaagattta ccttgaagca     6000

ctttccaaat tgatactttc aaacttattt taaagcagta gaaccttttc tatgaactaa     6060

atcacatgca aaactccaac ctgtagtata cataaaatgg acttacttat tcctctcacc     6120

ttctccagtg cctaggaata ttcttctctg agccctagga ttgattctat cacacagagc     6180

aacattaatc taaatggttt agctccctct tttttctcta aaaacaatca gctaataaaa     6240

aaaaaatttg agggcctaaa ttatttcaat ggttgtttga aatattcagt tcagtttgta     6300

cctgttagca gtctttcagt ttgggggaga attaaatact gtgctaagct ggtgcttgga     6360

tacatattac agcatcttgt gttttatttg acaaacagaa ttttggtgcc ataatatttt     6420

gagaattaga gaagattgtg atgcatatat ataaacacta tttttaaaaa atatctaaat     6480

atgtctcaca tatttatata atcctcaaat atactgtacc attttagata ttttttaaac     6540

agattaattt ggagaagttt tattcattac ctaattctgt ggcaaaaatg gtgcctctga     6600

tgttgtgata tagtattgtc agtgtgtaca tatataaaac ctgtgtaaac ctctgtcctt     6660

atgaaccata acaaatgtag ctttttaaag tccattgtat tgttttttct ttcaataaaa     6720

gagtataatt aa                                                         6732


<210>  786
<211>  4535
<212>  DNA
<213>  homo sapiens

<400>  786
gcgcgcgtgg aggcgggcgg cgggcgcaca gcagcagccc gggcggtggg cagccaggag       60

cccccggccc ggcccggccc ggcccgccga gggccccagc gcaggagccg cgcccggacc      120

caggcgatgc cctcctagct agccgtcacg ggatggaggg cttcatggac tcagggacac      180

agacggacgc cgtggtggtg ctgtccttgg ctcaggccgc cgtgcttggc ctggtctccg      240

aaaatgagct ctttggagct accataagcg ccgaggcctt ctacccggac ctggggcccg      300

agctttcagg ggcagccatg ggagagcccg agccaccagg ccccgacgtc taccagctgg      360

cctgcaacgg gagggccttg gaggagccgg cggaggagga ggtgctggag gtggaggcag      420

cctgtgagaa gcacacccgg cggaagacgc ggccacctgt gcggttggtg cccaaggtca      480

agttcgagaa ggtggaggag gaggaacagg aggtctatga ggtttctgtg ccaggtgacg      540

acaaggacgc agggccagca gaagcccccg ccgaggcggc cagtggcggc tgcgacgccc      600

tggtgcagag cagcgccgtc aagatgatcg acctcagcgc cttcagccgc aagccccgga      660

cgctccggca tctgccccga accccgaggc cggagctgaa cgtggcccca tatgaccctc      720

acttcccggc cccggcccgg gatggcttcc ccgagcccag catggcgctg cctgggccag      780

aggccttgcc cacagagtgt gggttcgagc caccccacct ggcccccctg agtgaccccg      840

aggcccccag catggagtcc ccggagcctg tcaagccgga acagggcttc gtgtggcagg      900

aggccagtga gttcgaggct gacacggcgg gttcgaccgt ggaacgccac aagaaggccc      960

agctggatcg gctggacatc aacgtgcaga ttgacgactc ctatctggtg gaggcgggcg     1020

accgccagaa gcgctggcag tgccgcatgt gcgagaagtc ctacacgtcc aagtacaacc     1080

tggtgacgca catcctgggc cacaacggca tcaagccaca ctcgtgccca cactgcagca     1140

agctcttcaa gcagcccagc cacctgcaga cgcacctgct gacgcaccag ggcacccggc     1200

cccacaagtg ccaggtatgc cacaaggcct tcacgcagac cagccacctc aagcgccaca     1260

tgctgctgca ctcggaggtc aagccctaca gctgccactt ctgcggccgc ggcttcgcct     1320

accccagcga gctcaaggcc cacgaagtga agcatgagag tggccgctgc catgtctgcg     1380

tcgagtgcgg cctggacttc tccaccctga cccagctcaa gcgccacctg gcctcccacc     1440

agggccccac cctctaccag tgcctcgagt gtgacaagtc cttccactac cgcagccagt     1500

tgcagaacca catgctcaag caccagaacg tgcgaccctt cgtgtgcact gaatgcggca     1560

tggagttcag ccagattcac cacctcaagc agcactccct cacccacaag ggcgtgaagg     1620

agttcaagtg cgaggtgtgt ggccgggagt tcaccctaca ggcgaacatg aagcggcaca     1680

tgctgatcca caccagcgtc cggccctacc agtgccacat ctgcttcaag acctttgtac     1740

agaagcagac tctcaagacc cacatgattg tacactcgcc cgtgaagcca ttcaaatgca     1800

aggtgtgcgg gaagtccttc aaccgcatgt acaacctgct gggccacatg cacctgcacg     1860

ccggcagcaa gcccttcaag tgcccctact gctccagcaa gtttaatctc aagggcaacc     1920

tgagccggca catgaaggtc aagcatggcg tcatggacat cggcctggac agccaagacc     1980

ccatgatgga gctgacaggc actgaccctt cagagctcga cggccagcag gagatggagg     2040

acttcgagga gaacgcctac agctatgcga gcgtggacag cagcgccgag gccagtgtcc     2100

tcactgaaca ggccatgaaa gagatggcct actacaatgt gctatagcgc aagctgggcc     2160

acccctaacg ggggccgggg gcgagggcat gggggtgaga cccatgggct gcaggctgca     2220

cctcctgcag ccgagaaaca agctactgcc ccactgttct gagccctccc tccccgagtc     2280

atttgcacca ctagggacct ttagaccaaa tggagactgt actactggcc ccggctgtga     2340

gccagcacag gcccaggcat cccagcaagg gaaggagaac acgcgaggcc cagatctggg     2400

tctccctggc ctgcttccgt ggggagtggg agaagtgggg ccactgggga caggtcacaa     2460

gggcaccggc cctcggggtc tctccaggcc cagcagagct cttcaggggt cctgacactg     2520

gaagaagaga ccacttgagc catgtctttt tcacggccaa ctcctgcctc taaggatgtc     2580

tgagctcccc tctggccagt actgcccacc tctaccttgt ccaggccccc ttccccgccc     2640

tgtcgacgga ccgccaggca gggcactctg ccttctacct cccggggtct cccatgcgct     2700

cctcaagcca ggtgtgcacg tggccctggc cctggcctgc aggacagctg gggggcaccc     2760

agcccccaga agacccctgt cctacatccc tttctggaag tgagtgtccc tacagtggat     2820

tgcaacacat gtcgtccact tcgaccctag ctggagtgcc tcaccagggg gccccactag     2880

gaacaaagcc aggacaggcc ccgcgtcagg cacacactaa caaaaccaga agcatggggc     2940

agggcagggc ggagtgaggg catcacaggg gaccaagaag ggctgtcctt gggggaggcc     3000

caggaccacc tgtcggggag ggggaccgca gtcatttctc attcctcagt gtccaccttg     3060

cgacggggat agccacgagt cagcagcttc ccggaaagag caacgtattt taaaaaggaa     3120

agtaaagccc acagagggaa atcaagggtt tttttgagca aagggggtct tctgaaggta     3180

acttattatt tttttctttc caactgtgtg tcacctatga ccttttctga tggagatgca     3240

ttttcttttt ccaagcgtaa gcttcctaat gtgctgtgcg tgcttcctac ccacccaccc     3300

cgagcagcct ggccgggcag gactggggct ccatggggac tgtcaccctg gccctggagg     3360

tgcagccgct ggcagcagcc tcagcaggct ggggtgggag gcaggagaag gcagagctgg     3420

gaagccctcc acccctgcct ggctcctgca gtcgctgact tgctctgtcc catgtcccat     3480

cctcggctgt cagggctgct gactctgctc agccaacagc tagctccctc gctcgcctgc     3540

tctcttcccc tctgttccca cgccagctcc tgcccctgga accagagatg acaggcccag     3600

ggcagtgaaa tagcacattc aggaactcta gggcacccgg acccccccac ccacttgcct     3660

cctgaggcct cagtggggag gggcaagcag gggtcttccc caaaggcaca gatgaagcca     3720

ctagcttcag cctagaaacc cggagaaggg aacagcctgc ggtgggagga accaatctgc     3780

agcgcagcca cccccaaggc tggatcctta agtgaaggac caagccaggc ctcagggtga     3840

ctgtgatcag gactgagggg tggacaaggt ggcccaagta tggcttccag accccgaagc     3900

cccacgacct cccaggtgcc cgccatgatg accctcaggt ggcagtgacc ccgtcactgt     3960

ataagacatt ttctcctgct gagcagaagg catcatcccc tgcaactacc tcttcccacg     4020

tctttctccc ctggtaccaa aaagaaccct gtacctctcc tcctcctcct ccctcctgcc     4080

agtgcagtgg ccttggtctt ggaaactgaa gggagaaggt ctggccccca gggtggggct     4140

ctcctttccc tcccccagcc ccgccgtcag cactggccct ctgtgaggtt cgatacttga     4200

acgccccctg ccctgtgcct tggacctggg caaagctagg aggaggaaac agcacaactc     4260

acagtttgag ctggggggtg gtcttggcaa ggctcctgtc tgtacccctc cctaaccttc     4320

tcaaaagagg tgcacagcct ctcgggtgac ttggaaactc ctggacaaat tccattctaa     4380

cttattttga catgtataca aaccaactgt ttagagattc cacttgtgca aagccctact     4440

gtgtttttat gttcctgttt aaaagagaag tttacttagc aataattata aataaatgaa     4500

tattctttag tgaggtgaaa aaaaaaaaaa aaaaa                                4535


<210>  787
<211>  2146
<212>  DNA
<213>  homo sapiens

<400>  787
tgcgtgccgc cgttgatccg gtgctgcagt gaggaggtgg ttcttgcccg tgttgtgtgt       60

gtgtgtgagt gagagagcga gtgagtgagt gagtgagtgt gtgtgtgggg gggactcggc      120

ttgttgttgt cggtgacttc cccctcccct tcaccccttc ccctccccgc cgccgctgca      180

gtggccgctc cctgggccgt aggaaatgag cgataacgat gacatcgagg tggagagcga      240

cgaagagcaa ccgaggtttc aatctgcggc tgacaaacgg gctcatcata atgcactgga      300

acgaaaacgt agggaccaca tcaaagacag ctttcacagt ttgcgggact cagtcccatc      360

actccaagga gagaaggcat cccgggccca aatcctagac aaagccacag aatatatcca      420

gtatatgcga aggaaaaacc acacacacca gcaagatatt gacgacctca agcggcagaa      480

tgctcttctg gagcagcaag gggaaagcga gagctgatca agttctttgt tcctggggaa      540

ttcacttctc ttcctccctc atggaagatg caagtaaaag gaaatgcaag taaccacctg      600

gtccgtgcac tggagaaggc gaggtcaagt gcccaactgc agaccaacta cccctcctca      660

gacaacagcc tctacaccaa cgccaagggc agcaccatct ctgccttcga tgggggctcg      720

gactccagct cggagtctga gcctgaagag ccccaaagca ggaagaagct ccggatggag      780

gccagctaag ccactcgggg caggccagca ataaaaactg tctgtctcca tcgtctcatc      840

ctcctttcag ttcgttggta gagccctcag aaccatttaa gagactcttt atttttctct      900

ttctcccttt tttttttaaa tttttatttt tacgtagaag ctcttggaca acagctctcg      960

ttctccttcc ccatttccac tgtatatttt ttaatgtatt cccttcaggg attccctgtc     1020

cccaacagga atttttaaac caaaacaccc caacttggca gctttttctg tggaggacag     1080

acggccggcc ggacctctga gcacatagtg tcctgcccac cctaccagct cctccagccc     1140

tgccgggcac atgcccgggg gacgcctgcc ctgcccaggt ggcctcctgg cccgccctca     1200

cctctgatag actttgtgaa tctgaactgc tctactttga gaagatgacc ggtttggagt     1260

aatcagaatg aaccctcctc ctttttaagg gttttttttt tttccttttt ctaaaaagct     1320

atgtatcgct cctattgaaa gaccagatcc ttagagaagt ttgtggtata aaaaggaagt     1380

ggggacagat tcgcagcaca gagtcgctgg catgtttcac tcctgcttct ctcagccagc     1440

tgtttaagcc tgcggcgcca gcctcacgga gggccgtgtg acactctcgt ggtatgtatg     1500

ggagatggca gcagtgaagc agcagccacc agggagtggc catttggggt tgggacaggg     1560

agggtgtttt gggtggcata gaggttttgt attgagggcc agtgatgatg ttttgatatt     1620

tatttcctgc tacttaaatt tgaatctgag tgaattgtac ctatttctga tgatgtcggt     1680

cttgcaaagc gacagattca taaagtaatg atgaaatctt tctttcttcc cgtgtgtatt     1740

tctaagaaat agagccaact gattttgtat gtaaatacca agagcaattt acctggtact     1800

aaacccgcac cccagtgcgg acccttccca gccctcatcc cacttccttt cctactgtcc     1860

tggaacctgt ctccattgtg tgatccagcc ctggttctgg ctgtggtcag cagatgccag     1920

tgaagggttt tgtgtgttta ggcctcattt ctttgtcttt ttcctactcc gttcctggca     1980

tttgctgatt tctagtgtat actctgtagt ctcagttcgt gtttgattcc attccatgga     2040

aataaaaagt atgttgtaca tactgccgaa gaattgtctt gcaagttaag gcttccccct     2100

ttactataag actataaata aaaacttatt ttatccttct taaaaa                    2146


<210>  788
<211>  2941
<212>  DNA
<213>  homo sapiens

<400>  788
cggccgctgc agcagcgcgg gccgggccag ggggcgcctc gcgcggcagc gactctggca       60

ggcgctgcag tgaagctgga cccgcaggcg ggcgtgcgtg gagcgggggc cgcggccgcg      120

ccgcagagat gtgactcggg ccgaaggcca gctggagcgt cggcgctgcg gggccgcggg      180

ggtcgaatgt tcgtggcatc agagagaaag atgagagctc accaggtgct caccttcctc      240

ctgctcttcg tgatcacctc ggtggcctct gaaaacgcca gcacatcccg aggctgtggg      300

ctggacctcc tccctcagta cgtgtccctg tgcgacctgg acgccatctg gggcattgtg      360

gtggaggcgg tggccggggc gggcgccctg atcacactgc tcctgatgct catcctcctg      420

gtgcggctgc ccttcatcaa ggagaaggag aagaagagcc ctgtgggcct ccactttctg      480

ttcctcctgg ggaccctggg cctctttggg ctgacgtttg ccttcatcat ccaggaggac      540

gagaccatct gctctgtccg ccgcttcctc tggggcgtcc tctttgcgct ctgcttctcc      600

tgcctgctga gccaggcatg gcgcgtgcgg aggctggtgc ggcatggcac gggccccgcg      660

ggctggcagc tggtgggcct ggcgctgtgc ctgatgctgg tgcaagtcat catcgctgtg      720

gagtggctgg tgctcaccgt gctgcgtgac acaaggccag cctgcgccta cgagcccatg      780

gactttgtga tggccctcat ctacgacatg gtactgcttg tggtcaccct ggggctggcc      840

ctcttcactc tgtgcggcaa gttcaagagg tggaagctga acggggcctt cctcctcatc      900

acagccttcc tctctgtgct catctgggtg gcctggatga ccatgtacct cttcggcaat      960

gtcaagctgc agcaggggga tgcctggaac gaccccacct tggccatcac gctggcggcc     1020

agcggctggg tcttcgtcat cttccacgcc atccctgaga tccactgcac ccttctgcca     1080

gccctgcagg agaacacgcc caactacttc gacacgtcgc agcccaggat gcgggagacg     1140

gccttcgagg aggacgtgca gctgccgcgg gcctatatgg agaacaaggc cttctccatg     1200

gatgaacaca atgcagctct ccgaacagca ggatttccca acggcagctt gggaaaaaga     1260

cccagtggca gcttggggaa aagacccagc gctccgttta gaagcaacgt gtatcagcca     1320

actgagatgg ccgtcgtgct caacggtggg accatcccaa ctgctccgcc aagtcacaca     1380

ggaagacacc tttggtgaaa gactttaagt tccagagaat cagaatttct cttaccgatt     1440

tgcctccctg gctgtgtctt tcttgaggga gaaatcggta acagttgccg aaccaggccg     1500

cctcacagcc aggaaatttg gaaatcctag ccaaggggat ttcgtgtaaa tgtgaacact     1560

gacgaactga aaagctaaca ccgactgccc gcccctcccc tgccacacac acagacacgt     1620

aataccagac caacctcaat ccccgcaaac taaagcaaag ctaattgcaa atagtattag     1680

gctcactgga aaatgtggct gggaagactg tttcatcctc tgggggtaga acagaaccaa     1740

attcacagct ggtgggccag actggtgttg gttggaggtg gggggctccc actcttatca     1800

cctctcccca gcaagtgctg gaccccaggt agcctcttgg agatgaccgt tgcgttgagg     1860

acaaatgggg actttgccac cggcttgcct ggtggtttgc acatttcagg ggggtcagga     1920

gagttaagga ggttgtgggt gggattccaa ggtgaggccc aactgaatcg tggggtgagc     1980

tttatagcca gtagaggtgg agggaccctg gcatgtgcca aagaagaggc cctctgggtg     2040

atgaagtgac catcacattt ggaaagtgat caaccactgt tccttctatg gggctcttgc     2100

tctagtgtct atggtgagaa cacaggcccc gccccttccc ttgtagagcc atagaaatat     2160

tctggcttgg ggcagcagtc ccttcttccc ttgatcatct cgccctgttc ctacacttac     2220

gggtgtatct ccaaatcctc tcccaatttt attcccttat tcatttcaag agctccaatg     2280

gggtctccag ctgaaagccc ctccgggagg caggttggaa ggcaggcacc acggcaggtt     2340

ttccgcgatg atgtcaccta gcagggcttc aggggttccc actaggatgc agagatgacc     2400

tctcgctgcc tcacaagcag tgacacctcg ggtcctttcc gttgctatgg tgaaaattcc     2460

tggatggaat ggatcacatg agggtttctt gttgcttttg gagggtgtgg gggatatttt     2520

gttttggttt ttctgcaggt tccatgaaaa cagccctttt ccaagcccat tgtttctgtc     2580

atggtttcca tctgtcctga gcaagtcatt cctttgttat ttagcatttc gaacatctcg     2640

gccattcaaa gcccccatgt tctctgcact gtttggccag cataacctct agcatcgatt     2700

caaagcagag ttttaacctg acggcatgga atgtataaat gagggtgggt ccttctgcag     2760

atactctaat cactacattg ctttttctat aaaactaccc ataagccttt aacctttaaa     2820

gaaaaatgaa aaaggttagt gtttgggggc cgggggagga ctgaccgctt cataagccag     2880

tacgtctgag ctgagtatgt ttcaataaac cttttgatat ttctcaaaaa aaaaaaaaaa     2940

a                                                                     2941


<210>  789
<211>  3982
<212>  DNA
<213>  homo sapiens

<400>  789
ggggatgcgg ctgtgggcgc cggggccggg tagctgctcc aggcgcgcga gctaaccgag       60

tgcggcgagg gcctaccagg ggcgacaggg tttctctccg caagcgcgcg atgcagcggg      120

cggcggcgct ggtccggcgg ggctgtggtc cccggacccc cagctcctgg ggccgcagcc      180

agagcagcgc ggccgccgag gcctcggcgg tgctcaaggt gcggcccgag cgcagccggc      240

gcgagcgcat cctcacgctg gagtccatga acccgcaggt gaaggcggtg gagtacgccg      300

tgcggggacc catcgtgctc aaggccggcg agatcgagct cgagctgcag cggggtatca      360

aaaagccatt cacagaggtc atccgagcca acatcgggga cgcccaggct atggggcagc      420

agccaatcac cttcctccgg caggtgatgg cactatgcac ctacccaaac ctgctggaca      480

gccccagctt cccagaagat gctaagaaac gtgcccggcg gatcctgcag gcttgtggcg      540

ggaacagcct ggggtcctac agtgctagcc agggtgtcaa ctgcatccgt gaagatgtgg      600

ctgcctacat caccaggagg gatggcggtg tgcctgcgga ccccgacaac atctacctga      660

ccacgggagc tagtgacggc atttctacga tcctgaagat cctcgtctcc gggggcggca      720

agtcacggac aggtgtgatg atccccatcc cacaatatcc cctctattca gctgtcatct      780

ctgagctcga cgccatccag gtgaattact acctggacga ggagaactgc tgggcgctga      840

atgtgaatga gctccggcgg gcggtgcagg aggccaaaga ccactgtgat cctaaggtgc      900

tctgcataat caaccctggg aaccccacag gccaggtaca aagcagaaag tgcatagaag      960

atgtgatcca ctttgcctgg gaagagaagc tctttctcct ggctgatgag gtgtaccagg     1020

acaacgtgta ctctccagat tgcagattcc actccttcaa gaaggtgctg tacgagatgg     1080

ggcccgagta ctccagcaac gtggagctcg cctccttcca ctccacctcc aagggctaca     1140

tgggcgagtg tggttacaga ggaggctaca tggaggtgat caacctgcac cctgagatca     1200

agggccagct ggtgaagctg ctgtcggtgc gcctgtgccc cccagtgtct gggcaggccg     1260

ccatggacat tgtcgtgaac cccccggtgg caggagagga gtcctttgag caattcagcc     1320

gagagaagga gtcggtcctg ggtaatctgg ccaaaaaagc aaagctgacg gaagacctgt     1380

ttaaccaagt cccaggaatt cactgcaacc ccttgcaggg ggccatgtac gccttccctc     1440

ggatcttcat tcctgccaaa gctgtggagg ctgctcaggc ccatcaaatg gctccagaca     1500

tgttctactg catgaagctc ctggaggaga ctggcatctg tgtcgtgccc ggcagtggct     1560

ttgggcagag ggaaggcact taccacttca ggatgactat cctccctcca gtggagaagc     1620

tgaaaacggt gctgcagaag gtgaaagact tccacatcaa cttcctggag aagtacgcgt     1680

gaggacgcct gagccccagc gggagacctg tccttggctc ttcctcccaa tgcccgtcag     1740

gctgaactcg cctcccccgt gactctgcct cgggcctcgc agaggccgct ggtcacttcg     1800

tcatcatttt gcccctggag acgtctttct ttgtgccttg atgttgagag cgcctctctt     1860

ttgagcaaac aagcattcta tatgcaacca gagtagaggg gacctgctca gcaggtgtga     1920

ccagggttct ctgaatctgt tattgttttt gcttctggaa agttcatttg gggtttacaa     1980

caactaggat gtgttgggtg agatgtttca gatctggaga aatgagcagg tgtcgggaaa     2040

tgtgtgactt aaccgtggtg agggctggaa atccaaactc accaccatga tctgtgaaat     2100

aaagccctta gcggtgtgaa gcatccggtc ctttgaacag aagggcctgg aaggcccctg     2160

gggctgagaa agggtccgcc cggtggcctg gaggcaggcg ccgggagcgc agtagcacgt     2220

ggactgggca ggatgttgca ctagcttggg gtagatgctg ggggctgcgg ccacggtcag     2280

agggccccac tgtgaggcgt gggtgtgagc caggctgcag gaggaactgg gcctccgctt     2340

cccagcaacg cagccaggcc tgagaattct gtgcgcccgg cgggctttgg gaatgagggg     2400

ttcccttgaa catgcgtagg ctggaacccc gtctgagagg tctccctgaa tttcagtgac     2460

acatagtgca gcccggcagt gtcccacttc cgtggagaga gccgctggaa tggtgtggac     2520

ccatcccgcg ggtgaccggt gcctgttctc ccctgaccga gcctgtgagc acatcgcccc     2580

ctgctggcga cagcggggaa atgagggctg aaaatatcct ccccacaagg gcaatccccg     2640

ggacctgccg agcagccaag gccctgtcct ttcttgaatg gtggcgagct gaatctggtc     2700

ggtttcctag cttttaggtg gtaaaagtgc ctggcagctt ggctgccgtg gaggagtcag     2760

tcgtggttgg aggttcattg ccgtgctttc atgcagagtg ttttgccttc atgttagctt     2820

ccggctcccc tcccaggctg cagactctga cctgtggcat caggcttctc ccagtacagg     2880

agggtgccat cccccagcat gcggcttctc tgccattagc agccctgggc gggccgacca     2940

cactcgaggc tgcggtgcta cgggcttagc cctcgcctcc ctcactggga gcttccccat     3000

cctccctgcc ttccccagtg ggaagttagg gaagctcagg agcctgggac cccgcatgtc     3060

ccaaaatggg attggagaag ctggagagaa agcagaagag gccgaggagt gaggcagcag     3120

cctctatgct gtgatttcca caccgggtcc gtgcagagga aacagaaact cccaactgtc     3180

cttacccacc gacatcacag cccctatgaa gaaagtagcc acaatctcaa ataacaaaag     3240

ggaatgttct aaaacttttt cttccttaaa aaatggagaa aattgcactt gtgcttgctg     3300

tgtggtatat aaaccaggat tagtcccagg gtcgtgaggt ttctggtgaa aaggttaaat     3360

cgtagaagct agtatatttt ttatattttt gtaacaattg cttttttcat gggggaggcg     3420

gggttagtat ttatagtcct aacaagtcca gtaatttttt ataaatcttc agattataaa     3480

cagcccctaa aaactttaca acgtttacac agttttttaa aaagagactg tatacacttg     3540

atttgctttc aaaataaata aggtcagcta gtctaggagg ttaacgtcgg gtaggaatgc     3600

tgatcatgat aggtttggtt ttctacagat tctgttccgg tgcctttcct atccaggcac     3660

cacctgagaa agttgtcatt tgaggtcgca cttggaagtt acatctgtga agtttctgtc     3720

attcgtccag atctgtgtgt gtagcatgtg ctgaggaagc acgtgctggg ctgtgcctca     3780

gacagtgcat caccgggcac ccagaggctt gcctggctat tcctgttctg gtgtgtgtgg     3840

agtgttgggg aggaacagat gcagatcaac ctgtggctgt tttcccgtct aggttctcac     3900

aggtatctcc tgacagaggt acttaacaat ggctctgctg gaaatttcta taaataaaat     3960

gtccaaaatg gtgactgcgt tt                                              3982


<210>  790
<211>  3958
<212>  DNA
<213>  homo sapiens

<400>  790
gttcacttac tggtgcccag caccgggcac tcagtgaggc cttgcaatac ggttcacttg       60

ttgaattgaa ttcgtcaatt gttgagcggg ccgtgctgcc aggcaccgca cgttgtgtgt      120

ctgccctact ctcgtggaac caaggtccag tggagagagg aacataagcg aatgaagaaa      180

gaagcaatag agtctcagtg ataagttctt ggaaaaaagg tctttgccaa tcctgattcc      240

cggaagagag tcggcagaat tccttccttt aggcccctct ggagccttgg ccgaccagcc      300

acttctgtgg tctggggaca gtcaccgagg gtatcaaaaa gccattcaca gaggtcatcc      360

gagccaacat cggggacgcc caggctatgg ggcagcagcc aatcaccttc ctccggcagg      420

tgatggcact atgcacctac ccaaacctgc tggacagccc cagcttccca gaagatgcta      480

agaaacgtgc ccggcggatc ctgcaggctt gtggcgggaa cagcctgggg tcctacagtg      540

ctagccaggg tgtcaactgc atccgtgaag atgtggctgc ctacatcacc aggagggatg      600

gcggtgtgcc tgcggacccc gacaacatct acctgaccac gggagctagt gacggcattt      660

ctacgatcct gaagatcctc gtctccgggg gcggcaagtc acggacaggt gtgatgatcc      720

ccatcccaca atatcccctc tattcagctg tcatctctga gctcgacgcc atccaggtga      780

attactacct ggacgaggag aactgctggg cgctgaatgt gaatgagctc cggcgggcgg      840

tgcaggaggc caaagaccac tgtgatccta aggtgctctg cataatcaac cctgggaacc      900

ccacaggcca ggtacaaagc agaaagtgca tagaagatgt gatccacttt gcctgggaag      960

agaagctctt tctcctggct gatgaggtgt accaggacaa cgtgtactct ccagattgca     1020

gattccactc cttcaagaag gtgctgtacg agatggggcc cgagtactcc agcaacgtgg     1080

agctcgcctc cttccactcc acctccaagg gctacatggg cgagtgtggt tacagaggag     1140

gctacatgga ggtgatcaac ctgcaccctg agatcaaggg ccagctggtg aagctgctgt     1200

cggtgcgcct gtgcccccca gtgtctgggc aggccgccat ggacattgtc gtgaaccccc     1260

cggtggcagg agaggagtcc tttgagcaat tcagccgaga gaaggagtcg gtcctgggta     1320

atctggccaa aaaagcaaag ctgacggaag acctgtttaa ccaagtccca ggaattcact     1380

gcaacccctt gcagggggcc atgtacgcct tccctcggat cttcattcct gccaaagctg     1440

tggaggctgc tcaggcccat caaatggctc cagacatgtt ctactgcatg aagctcctgg     1500

aggagactgg catctgtgtc gtgcccggca gtggctttgg gcagagggaa ggcacttacc     1560

acttcaggat gactatcctc cctccagtgg agaagctgaa aacggtgctg cagaaggtga     1620

aagacttcca catcaacttc ctggagaagt acgcgtgagg acgcctgagc cccagcggga     1680

gacctgtcct tggctcttcc tcccaatgcc cgtcaggctg aactcgcctc ccccgtgact     1740

ctgcctcggg cctcgcagag gccgctggtc acttcgtcat cattttgccc ctggagacgt     1800

ctttctttgt gccttgatgt tgagagcgcc tctcttttga gcaaacaagc attctatatg     1860

caaccagagt agaggggacc tgctcagcag gtgtgaccag ggttctctga atctgttatt     1920

gtttttgctt ctggaaagtt catttggggt ttacaacaac taggatgtgt tgggtgagat     1980

gtttcagatc tggagaaatg agcaggtgtc gggaaatgtg tgacttaacc gtggtgaggg     2040

ctggaaatcc aaactcacca ccatgatctg tgaaataaag cccttagcgg tgtgaagcat     2100

ccggtccttt gaacagaagg gcctggaagg cccctggggc tgagaaaggg tccgcccggt     2160

ggcctggagg caggcgccgg gagcgcagta gcacgtggac tgggcaggat gttgcactag     2220

cttggggtag atgctggggg ctgcggccac ggtcagaggg ccccactgtg aggcgtgggt     2280

gtgagccagg ctgcaggagg aactgggcct ccgcttccca gcaacgcagc caggcctgag     2340

aattctgtgc gcccggcggg ctttgggaat gaggggttcc cttgaacatg cgtaggctgg     2400

aaccccgtct gagaggtctc cctgaatttc agtgacacat agtgcagccc ggcagtgtcc     2460

cacttccgtg gagagagccg ctggaatggt gtggacccat cccgcgggtg accggtgcct     2520

gttctcccct gaccgagcct gtgagcacat cgccccctgc tggcgacagc ggggaaatga     2580

gggctgaaaa tatcctcccc acaagggcaa tccccgggac ctgccgagca gccaaggccc     2640

tgtcctttct tgaatggtgg cgagctgaat ctggtcggtt tcctagcttt taggtggtaa     2700

aagtgcctgg cagcttggct gccgtggagg agtcagtcgt ggttggaggt tcattgccgt     2760

gctttcatgc agagtgtttt gccttcatgt tagcttccgg ctcccctccc aggctgcaga     2820

ctctgacctg tggcatcagg cttctcccag tacaggaggg tgccatcccc cagcatgcgg     2880

cttctctgcc attagcagcc ctgggcgggc cgaccacact cgaggctgcg gtgctacggg     2940

cttagccctc gcctccctca ctgggagctt ccccatcctc cctgccttcc ccagtgggaa     3000

gttagggaag ctcaggagcc tgggaccccg catgtcccaa aatgggattg gagaagctgg     3060

agagaaagca gaagaggccg aggagtgagg cagcagcctc tatgctgtga tttccacacc     3120

gggtccgtgc agaggaaaca gaaactccca actgtcctta cccaccgaca tcacagcccc     3180

tatgaagaaa gtagccacaa tctcaaataa caaaagggaa tgttctaaaa ctttttcttc     3240

cttaaaaaat ggagaaaatt gcacttgtgc ttgctgtgtg gtatataaac caggattagt     3300

cccagggtcg tgaggtttct ggtgaaaagg ttaaatcgta gaagctagta tattttttat     3360

atttttgtaa caattgcttt tttcatgggg gaggcggggt tagtatttat agtcctaaca     3420

agtccagtaa ttttttataa atcttcagat tataaacagc ccctaaaaac tttacaacgt     3480

ttacacagtt ttttaaaaag agactgtata cacttgattt gctttcaaaa taaataaggt     3540

cagctagtct aggaggttaa cgtcgggtag gaatgctgat catgataggt ttggttttct     3600

acagattctg ttccggtgcc tttcctatcc aggcaccacc tgagaaagtt gtcatttgag     3660

gtcgcacttg gaagttacat ctgtgaagtt tctgtcattc gtccagatct gtgtgtgtag     3720

catgtgctga ggaagcacgt gctgggctgt gcctcagaca gtgcatcacc gggcacccag     3780

aggcttgcct ggctattcct gttctggtgt gtgtggagtg ttggggagga acagatgcag     3840

atcaacctgt ggctgttttc ccgtctaggt tctcacaggt atctcctgac agaggtactt     3900

aacaatggct ctgctggaaa tttctataaa taaaatgtcc aaaatggtga ctgcgttt       3958


<210>  791
<211>  2471
<212>  DNA
<213>  homo sapiens

<400>  791
gcgttacagg ccctttggcg cctgcgtatt cgtgaagtgt gaaaaaagcg cgcctctgtt       60

gggacgggaa atcagccttt ctattggtca gggttagaaa ccccgccttt gaggcatttt      120

caaccaatgg aagcgcggca ttcttcattt aaactgtcta taaatttctg cctagtcaaa      180

gttaagagtg gcgccaggga tttgaaccgc gctgacgaag tttggtgatc catcttccga      240

gtatcgccgg gatttcgaat cgcgatgatc atcccctctc tagaggagct ggactccctc      300

aagtacagtg acctgcagaa cttagccaag agtctgggtc tccgggccaa cctgagggca      360

accaagttgt taaaagcctt gaaaggctac attaaacatg aggcaagaaa aggaaatgag      420

aatcaggatg aaagtcaaac ttctgcatcc tcttgtgatg agactgagat acagatcagc      480

aaccaggaag aagctgagag acagccactt ggccatgtca ccaaaacaag gagaaggtgc      540

aagactgtcc gtgtggaccc tgactcacag cagaatcatt cagagataaa aataagtaat      600

cccactgaat tccagaatca tgaaaagcag gaaagccagg atctcagagc tactgcaaaa      660

gttccttctc caccagacga gcaccaagaa gctgagaatg ctgtttcctc aggtaacaga      720

gattcaaagg taccttcaga aggaaagaaa tctctctaca cagatgagtc atccaaacct      780

ggaaaaaata aaagaactgc aatcactact ccaaacttta agaagcttca tgaagctcat      840

tttaaggaaa tggagtccat tgatcaatat attgagagaa aaaagaaaca ttttgaagaa      900

cacaattcca tgaatgaact gaagcagcag cccatcaata agggaggggt caggactcca      960

gtacctccaa gaggaagact ctctgtggct tctactccca tcagccaacg acgctcgcaa     1020

ggccggtctt gtggccctgc aagtcagagt accttgggtc tgaaggggtc actcaagcgc     1080

tctgctatct ctgcagctaa aacgggtgtc aggttttcag ctgctactaa agataatgag     1140

cataagcgtt cactgaccaa gactccagcc agaaagtctg cacatgtgac cgtgtctggg     1200

ggcaccccaa aaggcgaggc tgtgcttggg acacacaaat taaagaccat cacggggaat     1260

tctgctgctg ttattacccc attcaagttg acaactgagg caacgcagac tccagtctcc     1320

aataagaaac cagtgtttga tcttaaagca agtttgtctc gtcccctcaa ctatgaacca     1380

cacaaaggaa agctaaaacc atgggggcaa tctaaagaaa ataattatct aaatcaacat     1440

gtcaacagaa ttaacttcta caagaaaact tacaaacaac cccatctcca gacaaaggaa     1500

gagcaacgga agaaacgcga gcaagaacga aaggagaaga aagcaaaggt tttgggaatg     1560

cgaaggggcc tcattttggc tgaagattaa taatttttta acatcttgta aatattcctg     1620

tattctcaac ttttttcctt ttgtaaattt tttttttttg ctgtcatccc cactttagtc     1680

acgagatctt tttctgctaa ctgttcatag tctgtgtagt gtccatgggt tcttcatgtg     1740

ctatgatctc tgaaaagacg ttatcacctt aaagctcaaa ttctttggga tggtttttac     1800

ttaagtccat taacaattca ggtttctaac gagacccatc ctaaaattct gtttctagat     1860

ttttaatgtc aagttcccaa gttccccctg ctggttctaa tattaacaga actgcagtct     1920

tctgctagcc aatagcattt acctgatggc agctagttat gcaagcttca ggagaatttg     1980

aacaataaca agaatagggt aagctgggat agaaaggcca cctcttcact ctctatagaa     2040

tatagtaacc tttatgaaac ggggccatat agtttggtta tgacatcaat attttaccta     2100

ggtgaaattg tttaggctta tgtaccttcg ttcaaatatc ctcatgtaat tgccatctgt     2160

cactcactat attcacaaaa ataaaactct acaactcatt ctaacattgc ttacttaaaa     2220

gctacatagc cctatcgaaa tgcgaggatt aatgctttaa tgcttttaga gacagggtct     2280

cactgtgttg cccaggctgg tctcaaactc caccaaatgt acttcttatt cattttatgg     2340

aaaagactag gctttgctta gtatcatgtc catgtttcct tcacctcagt ggagcttctg     2400

agttttatac tgctcaagat cgtcataaat aaaatttttt ctcattgtca tagaaaaaaa     2460

aaaaaaaaaa a                                                          2471


<210>  792
<211>  5554
<212>  DNA
<213>  homo sapiens

<400>  792
ccccgccccg caggctgccg ggggcccacc gccgcccagg caaggccgcc ctgccttggg       60

cgcagcgctg ccatggctgg gggccgtggg gcccccgggc gcggccggga cgagcctccg      120

gagagctacc cgcaacgaca ggaccacgag ctacaggccc tggaggccat ttacggcgcg      180

gacttccaag acctgcggcc ggacgcttgc ggaccggtca aagagccccc tgaaatcaat      240

ttagttttgt accctcaagg cctaactggt gaagaagtat atgtaaaagt ggatttgagg      300

gttaaatgcc cacctaccta tccagatgta gttcctgaaa tagagttaaa aaatgccaaa      360

ggtctatcaa atgaaagtgt caatttgtta aaatctcgcc tagaagaact ggccaagaaa      420

cactgtgggg aggtgatgat ctttgaactg gcttaccacg tgcagtcatt tctcagcgag      480

cataacaagc cccctcccaa gtcttttcat gaagaaatgc tggaaaggcg ggctcaggag      540

gagcagcaga ggctgttgga ggccaagcgg aaagaagagc aggagcaacg tgaaatcctg      600

catgagattc agagaaggaa agaagagata aaagaagaga aaaaaaggaa agaaatggct      660

aagcaggaac gtttggaaat tgctagtttg tcaaaccaag atcatacctc taagaaggac      720

ccaggaggac acagaacggc tgccattcta catggaggct ctcctgactt tgtaggaaat      780

ggtaaacatc gggcaaactc ctcaggaagg tctaggcgag aacgtcagta ttctgtatgt      840

aatagtgaag attctcctgg ctcttgtgaa attctgtatt tcaatatggg gagtcctgat      900

cagctcatgg tgcacaaagg gaaatgtatt ggcagtgatg aacaacttgg aaaattagtc      960

tacaatgctt tggaaacagc cactggtggc tttgtcttgt tgtatgagtg ggtccttcag     1020

tggcagaaaa aaatgggtcc attccttacc agtcaagaaa aagagaagat tgataagtgc     1080

aaaaagcaga ttcaaggaac agaaacagaa ttcaactcac tggtaaaatt gagccatcca     1140

aatgtagtac gctaccttgc aatgaatctc aaagagcaag acgactccat cgtggtggac     1200

attttagtgg agcacattag tggggtctct cttgctgcac acctgagcca ctcaggcccc     1260

atccctgtgc atcagcttcg caggtacaca gctcagctcc tgtcaggcct tgattatctg     1320

cacagcaatt ctgtggtgca taaggtcctg agtgcatcta atgtcttggt ggatgcagaa     1380

ggcaccgtca agattacgga ctatagcatt tctaagcgcc tcgcagacat ttgcaaggag     1440

gatgtgtttg agcaaacccg agttcgtttt agtgacaatg ctctgcctta taaaacgggg     1500

aagaaaggag atgtttggcg tcttggcctt ctgctgctgt ccctcagcca aggacaggaa     1560

tgtggagagt accctgtgac catccctagt gacttaccag ctgactttca agattttcta     1620

aagaaatgtg tgtgcttgga tgacaaggaa agatggagtc cccagcagtt gttgaaacac     1680

agctttataa atccccagcc aaaaatgcct ctagtggaac aaagtcctga agattctgaa     1740

ggacaagatt atgttgagac tgttattcct agcaaccggc tacccagtgc tgccttcttt     1800

agtgagacac agagacagtt ttcccgatac ttcattgagt ttgaagaatt acaacttctt     1860

ggtaaaggag cttttggagc tgtcatcaag gtgcagaaca agttggacgg ctgctgctac     1920

gcagtgaagc gcatccccat caacccggcc agccggcagt tccgcaggat caagggcgaa     1980

gtgacactgc tgtcacggct gcaccatgag aacattgtgc gctactacaa cgcctggatc     2040

gagcggcacg agcggccggc gggaccgggg acgccgcccc cggactccgg gcccctggcc     2100

aaggatgacc gagctgcacg cgggcagccg gcgagcgaca cagacggcct ggacagcgta     2160

gaggccgccg cgccgccacc catcctcagc agctcggtgg agtggagcac ttcgggcgag     2220

cgctcggcca gtgcccgttt ccccgccacc ggcccgggct ccagcgatga cgaggacgac     2280

gacgaggacg agcacggtgg cgtcttctcc cagtccttcc tgcctgcttc agattctgaa     2340

agtgatatta tctttgacaa tgaagatgag aacagtaaaa gtcagaatca ggatgaagat     2400

tgcaatgaaa agaatggctg ccatgaaagt gagccatcag tgacgactga ggctgtgcac     2460

tacctataca tccagatgga gtactgtgag aagagcactt tacgagacac cattgaccag     2520

ggactgtatc gagacaccgt cagactctgg aggctttttc gagagattct ggatggatta     2580

gcttatatcc atgagaaagg aatgattcac cgggatttga agcctgtcaa catttttttg     2640

gattctgatg accatgtgaa aataggtgat tttggtttgg cgacagacca tctagccttt     2700

tctgctgaca gcaaacaaga cgatcagaca ggagacttga ttaagtcaga cccttcaggt     2760

cacttaactg ggatggttgg cactgctctc tatgtaagcc cagaggtcca aggaagcacc     2820

aaatctgcat acaaccagaa agtggatctc ttcagcctgg gaattatctt ctttgagatg     2880

tcctatcacc ccatggtcac ggcttcagaa aggatctttg ttctcaacca actcagagat     2940

cccacttcgc ctaagtttcc agaagacttt gacgatggag agcatgcaaa gcagaaatca     3000

gtcatctcct ggctgttgaa ccacgatcca gcaaaacggc ccacagccac agaactgctc     3060

aagagtgagc tgctgccccc accccagatg gaggagtcag agctgcatga agtgctgcac     3120

cacacgctga ccaacgtgga tgggaaggcc taccgcacca tgatggccca gatcttctcg     3180

cagcgcatct cccctgccat cgattacacc tatgacagcg acatactgaa gggcaacttc     3240

tcaatccgta cagccaagat gcagcagcat gtgtgtgaaa ccatcatccg catctttaaa     3300

agacatggag ctgttcagtt gtgtactcca ctactgcttc cccgaaacag acaaatatat     3360

gagcacaacg aagctgccct attcatggac cacagcggga tgctggtgat gcttcctttt     3420

gacctgcgga tcccttttgc aagatatgtg gcaagaaata atatattgaa tttaaaacga     3480

tactgcatag aacgtgtgtt caggccgcgc aagttagatc gatttcatcc caaagaactt     3540

ctggagtgtg catttgatat tgtcacttct accaccaaca gctttctgcc cactgctgaa     3600

attatctaca ctatctatga aatcatccaa gagtttccag cacttcagga aagaaattac     3660

agtatttatt tgaaccatac catgttattg aaagcaatac tcttacactg tgggatccca     3720

gaagataaac tcagtcaagt ctacattatt ctgtatgatg ctgtgacaga gaagctgacg     3780

aggagagaag tggaagctaa attttgtaat ctgtctttgt cttctaatag tctgtgtcga     3840

ctctacaagt ttattgaaca gaagggagat ttgcaagatc ttatgccaac aataaattca     3900

ttaataaaac agaaaacagg tattgcacag ttggtgaagt atggcttaaa agacctagag     3960

gaggttgttg gactgttgaa gaaactcggc atcaagttac aggtcttgat caatttgggc     4020

ttggtttaca aggtgcagca gcacaatgga atcatcttcc agtttgtggc tttcatcaaa     4080

cgaaggcaaa gggctgtacc tgaaatcctc gcagctggag gcagatatga cctgctgatt     4140

ccccagttta gagggccaca agctctgggg ccagttccca ctgccattgg ggtcagcata     4200

gctatagaca agatatctgc tgctgtcctc aacatggagg aatctgttac aataagctct     4260

tgtgacctcc tggttgtaag tgttggccag atgtctatgt ccagggccat caacctaacc     4320

cagaaactct ggacagcagg catcacagca gaaatcatgt acgactggtc acagtcccaa     4380

gaggaattac aagagtactg cagacatcat gaaatcacct atgtggccct tgtctcggat     4440

aaagaaggaa gccatgtcaa ggttaagtct ttcgagaagg aaaggcagac agagaagcgt     4500

gtgctggaga ctgaacttgt ggaccatgta ctgcagaaac tgaggactaa agtcactgat     4560

gaaaggaatg gcagagaagc ttccgataat cttgcagtgc aaaatctgaa ggggtcattt     4620

tctaatgctt caggtttgtt tgaaatccat ggagcaacag tggttcccat tgtgagtgtg     4680

ctagccccgg agaagctgtc agccagcact aggaggcgct atgaaactca ggtacaaact     4740

cgacttcaga cctcccttgc caacttacat cagaaaagca gtgaaattga aattctggct     4800

gtggatctac ccaaagaaac aatattacag tttttatcat tagagtggga tgctgatgaa     4860

caggcattta acacaactgt gaagcagctg ctgtcacgcc tgccaaagca aagatacctc     4920

aaattagtct gtgatgaaat ttataacatc aaagtagaaa aaaaggtgtc tgtgctattt     4980

ctgtacagct atagagatga ctactacaga atcttatttt aaccctaaag aactgtcgtt     5040

aacctcattc aaacagacag aggcttatac tggaataatg gaatgttgta cattcatcat     5100

aatttaaaat taaattctaa gaagaggctg ggtgcagtgg ctcacacctt taatcccagc     5160

actttgggaa gccaaggcag gaagactgct tgaaaccagg agtttgagac cagcctgagc     5220

aacaaagcaa gaccccatct ctataaaaac taaaaaaatt agttgggcat ggtggcacat     5280

gcctgtagtc ccagctactc cagaggctga gatggatcat ctgagcctca ggaggttgag     5340

gctgcagtga gctgtgactg cgccactgca ctccagtctg ggacaacaga gcaagaccct     5400

gtcttaaaaa aaaaaagaaa aaaaaaattt ttttctaaga agctgtccta caaagttgag     5460

ctttgttagt ttttcatgtg taatatatta taaatttatc ttttgggata taataaatgc     5520

tttcatatac ctgcaaaaaa aaaaaaaaaa aaaa                                 5554


<210>  793
<211>  5305
<212>  DNA
<213>  homo sapiens

<400>  793
tccttccttt ccgtctctgg ccggctgggc gcgggcgact gctggcgagg cgcgtgggac       60

cttacgctgg ttccccttcg tctcctctcc cggcccgggc cactagagag ttcgctgacg      120

ccgggtgagc tgagcctgcc gccaagatgc cggcctattt tcagaggccg gaaaatgccc      180

tcaaacgcgc caacgaattt cttgaggttg gcaaaaagca gcctgctctg gatgttcttt      240

atgatgttat gaaaagtaaa aaacatagaa catggcaaaa gatacacgaa ccaattatgt      300

tgaaatactt ggaactttgc gtggatcttc gcaagagcca cttggcaaag gaggggttat      360

accagtataa gaacatttgt caacaggtga acataaaatc tctggaggat gttgttaggg      420

catatttgaa aatggcagag gaaaaaactg aagctgctaa agaagaatct cagcagatgg      480

tcttagatat agaggatcta gataatattc aaactcctga gagtgttctc ctaagtgctg      540

taagtggtga agacactcag gatcgtactg acagattact tttaactcca tgggttaaat      600

tcctgtggga gtcttacagg cagtgtttgg accttcttag aaacaattct agagtagagc      660

gcctgtacca tgatattgcc cagcaagctt tcaaattctg cctccaatac acgcgtaagg      720

ctgaattccg taaactgtgt gacaatttga gaatgcactt atcgcagatt cagcgccacc      780

ataaccaaag tacggcaatc aatcttaata atccagagag ccagtccatg catttggaaa      840

ccagacttgt tcagctggac agtgctatca gcatggaatt gtggcaggaa gcattcaaag      900

ctgtggaaga tattcacggg ctattctcct tgtctaaaaa accacctaaa cctcagttga      960

tggcaaatta ctataacaaa gtctcaactg tgttttggaa atctggaaat gctctttttc     1020

atgcatctac actccatcgt ctttaccatc tctctagaga aatgagaaag aatctcacac     1080

aagatgagat gcaaagaatg tctactagag tccttttagc cactctttcc atccctatta     1140

ctcctgagcg tacggatatt gctcgacttc tggatatgga tggcattata gttgaaaaac     1200

agcgtcgcct tgcaacacta ctaggtcttc aagccccacc gacacgaatt ggccttatta     1260

atgatatggt cagatttaat gtactacaat atgttgtccc agaagtgaaa gacctttaca     1320

attggcttga agtagaattt aacccattaa aactctgtga gcgagtcaca aaggttctaa     1380

attgggttag ggaacaacct gaaaaggaac cggaattgca gcagtatgtg ccacaactgc     1440

aaaacaacac catcctccgc cttctgcagc aggtgtcaca gatttatcag agcattgagt     1500

tttctcgttt gacttctttg gttccttttg ttgatgcttt ccaactggaa cgggccatag     1560

tagatgcagc caggcattgc gacttgcagg ttcgtattga tcacacttct cggaccctga     1620

gttttggatc tgatttgaat tatgctactc gagaagatgc tccgattggt cctcatttgc     1680

aaagcatgcc ttcagagcag ataagaaacc agctgacagc catgtcctca gtacttgcaa     1740

aagcacttga agtcattaaa ccagctcata tactgcaaga gaaagaagaa cagcatcagt     1800

tggctgtcac tgcatacctt aaaaattcac gaaaagagca ccagcggatc ctggctcgcc     1860

gccagacaat tgaggagaga aaagagcgcc ttgagagtct gaatattcag cgtgagaaag     1920

aagaattgga acagagggaa gctgaactcc agaaagtgcg gaaggctgag gaagagaggc     1980

tgcgccagga agcaaaggag agagagaagg agcgtatctt acaggaacat gaacaaatca     2040

aaaagaaaac tgtccgagag cgtttggagc agatcaagaa aacagaactg ggtgccaaag     2100

cattcaaaga tattgatatt gaagaccttg aggaattgga tccagatttt atcatggcta     2160

aacaggttga acaactggag aaagaaaaga aagaacttca agaacgccta aagaatcaag     2220

aaaagaagat tgactatttt gaaagagcca aacgtttgga agaaattcct ttgataaaga     2280

gcgcttacga ggaacagaga attaaagaca tggatctgtg ggagcaacaa gaggaagaaa     2340

gaattactac aatgcagcta gaacgtgaaa aggctcttga acataagaat cgaatgtcac     2400

gaatgcttga agacagagat ttattcgtaa tgcgactcaa agctgcacgg cagtctgttt     2460

atgaggaaaa acttaaacag tttgaagagc gattagcaga agaaaggcat aatcgattgg     2520

aagaacggaa aaggcagcgt aaagaagaac gcaggataac atactataga gaaaaagaag     2580

aggaggagca gagaagggca gaagaacaaa tgctaaaaga gcgggaagag agagagcgcg     2640

ccgaacgagc aaaacgcgag gaagagctac gagagtatca ggagcgggtg aagaaattag     2700

aagaagtgga aaggaaaaaa cgccaaaggg agttggaaat tgaagaacga gaacggcgta     2760

gagaggaaga gagaagactt ggcgatagtt ccctttctag aaaggactct cgttggggag     2820

atagagattc agaaggcacc tggagaaaag gacctgaagc agattctgag tggagaagag     2880

gcccgccaga gaaggagtgg agacgtggag aagggcgaga tgaggacagg tctcatagaa     2940

gagatgaaga gcggccccgg cgtctggggg atgatgaaga tagagagccc tctcttagac     3000

cagacgatga tcgggttccc cggcgtggca tggatgatga cagaggccct agacgtggtc     3060

ctgaggaaga taggttctct cgtcgtgggg cagacgatga ccggccttcc tggcgtaaca     3120

cagatgatga caggcctccc agacgaattg ccgatgaaga caggggaaac tggcgtcatg     3180

cggatgatga cagaccacct agacgaggac tggatgagga cagaggaagc tggcgaacag     3240

ctgatgagga cagaggacca agacgtggga tggatgatga ccgggggccg aggcgaggag     3300

gcgctgatga tgagcgatca tcctggcgta atgctgatga tgaccggggt cccaggcgag     3360

ggttggatga tgatcggggt cccaggcgag gcatggatga tgaccggggt cccaggcgag     3420

gcatggatga tgaccggggt cccaggcgag gcatggatga tgaccggggt cccaggcgag     3480

ggttggatga tgatcgagga ccttggagga acgccgatga tgacagaatt cccaggcgtg     3540

gtgcagagga tgacaggggc ccttggagaa acatggatga tgatcgcctt tcaagacgtg     3600

ctgatgatga tcggtttccc agacggggtg atgactcaag acctggtcct tggagaccat     3660

tagtcaagcc aggtggatgg agagagaaag aaaaagccag agaggagagc tggggtccac     3720

ctcgagaatc aaggccatca gaagaacgtg aatgggacag agaaaaagaa agggacagag     3780

ataatcaaga tcgggaggag aatgacaagg accctgagag agaaagggac agagagagag     3840

atgtggatcg agaggatcgc ttcagaagac ctagggatga aggtggctgg agaagaggac     3900

cagctgagga atcttcaagc tggagagact caagtcgccg ggacgatagg gatagggatg     3960

accgtcgccg tgagagggat gaccggcgtg atctaagaga aagacgagat ctaagagacg     4020

acagggaccg aagaggacct ccactcagat cagaacgtga agaagtaagt tcttggagac     4080

gtgctgatga caggaaagat gaccgggtgg aagagcggga ccctcctcgt cgagttcctc     4140

ccccagctct ttcaagagac cgagaaagag accgagaccg agaaagagaa ggtgaaaaag     4200

agaaggcctc atggagagct gagaaagata gggaatctct ccgtcgtact aaaaatgaga     4260

ctgatgaaga tggatggacc acagtacgac gttaagtctc aagataatgg atttaaactg     4320

gtgtcttaaa taggtttgat cacattcaag gattattata cttgtgcttc aaccaatcta     4380

aattggattc tttaatgttg tttcaccata acacaaaaag catgaacttg tattaatcct     4440

atataataga ttgatcatgc accatatcca caggaggttg gaaaaaccat gccattttct     4500

ggaatttaag ggtgttgcat tatttcatca atcatttgtt gacaaaaaag aaaaactaaa     4560

aaataaattt aaaatgtgac ccttcaggta ttgagtaaca cctttatctt ggtatagaac     4620

tgatactttt tttttgattt tgaaatatct gataataatt tggaatgaag taaggttctg     4680

ttaaaatata tttgaagacc ctttaaagca gtgaatctga aacaattttc acacccttaa     4740

gtggttgata cgtacctatt ttaggtattt tgaggtattt accataaact aaatttagaa     4800

attttttaga ttcacttgaa gtaaacatta caaacattgg atacggtggg gttttcttta     4860

gattttactt gagagaaggt gagtacaaag caatttgcag ttgttgtaat gacaagatta     4920

ctgcgcaagt gtgaatccaa acagtatagc ttttaaattt taaagcattt ggtaaattat     4980

cgctgagttt ttttctgttg ccaatagcaa actgcttttc cattaatgga gaattcatgc     5040

ctttcaagca ttttaaatat gacaatattt ataaatgtat ggtttggagg aatcgtttaa     5100

attctctttc ctaattttct ttcttttgaa gatagattct ttcaacaagt aatttgtagt     5160

aatgactgtg ttgacttcaa ttttggagcg cagtagctat gttaaagatg aactatttgg     5220

tctcattgaa gccaacacag aacttgctgc tgtgtttttt cttcagtgat aaataaaata     5280

cttacagaat ttgttttagt gttga                                           5305


<210>  794
<211>  6275
<212>  DNA
<213>  homo sapiens

<400>  794
ggaatgcggc tgcgcactgg gcgctctcgc ccgagaagcc gcagtctcga gagcgtcaac       60

gaggtgtttc ggtagtctct ggccatcctt tctgcgcacc cggtgtcgct gggctgcacc      120

ccgggcgggg acgtccgccg ggcacgggag ggggccaaga tgccgatcaa taaatcagag      180

aagccagaaa gctgcgataa tgtgaaggtt gttgttaggt gccggcccct caatgagaga      240

gagaaatcaa tgtgctacaa acaggctgtc agtgtggatg agatgagggg aactatcact      300

gtacataaga ctgattcttc caatgaacct ccaaagacat ttacttttga tactgttttt      360

ggaccagaga gtaaacaact tgatgtttat aacttaactg caagacctat tattgattct      420

gtacttgaag gctacaatgg gactattttt gcatatggac aaaccggaac aggcaaaact      480

tttaccatgg aaggtgttcg agctattcct gaacttagag gaataattcc caattcattt      540

gctcacatat ttggtcatat tgcaaaagcg gagggtgata caagattttt ggttcgagtg      600

tcttatttgg aaatatataa tgaagaagtt cgtgaccttt tgggcaagga tcagacacaa      660

aggttagagg ttaaagaaag acctgatgtg ggagtttata tcaaagattt atcagcttat      720

gtggtaaata atgctgatga tatggataga attatgacgc taggccacaa aaatcgttct      780

gttggtgcaa ctaatatgaa cgaacatagt tcccgttccc atgccatctt tacaattact      840

atagaatgca gtgaaaaagg cattgatggt aacatgcatg tcaggatggg gaagctccat      900

cttgtagatc ttgctggttc agaaagacag gcaaaaactg gagctactgg acagcgccta      960

aaggaagcta caaaaatcaa tctttcactt tccacccttg gtaatgtaat ttctgccttg     1020

gttgatggaa aaagcactca tgtgccttat cgtaactcta aactgactcg tcttcttcag     1080

gattccttag gaggaaattc aaaaaccatg atgtgtgcaa atattgggcc agcagattac     1140

aattatgatg aaactatcag tacattacgg tatgccaatc gtgctaagaa tattaaaaat     1200

aaagctagaa ttaatgaaga tccaaaggat gctttgctgc gtcagttcca gaaagaaata     1260

gaagaactga aaaagaagct tgaagaagga gaagaaatat caggctctga tatcagtggg     1320

tcagaggaag atgatgatga agagggtgag gttggagaag atggagagaa aaggaaaaaa     1380

agaaggggaa aaaagaaagt ctccccagac aagatgattg aaatgcaagc aaaaattgat     1440

gaggagagaa aagcacttga aacaaagctc gacatggaag aagaagaaag aaacaaggct     1500

agagctgaat tagagaaacg ggaaaaagat cttcttaaag cccaacaaga gcatcagtct     1560

ttgctggaaa aattatctgc cctggaaaag aaggtaattg ttggtggggt tgacttgttg     1620

gccaaagctg aggaacaaga gaaacttctt gaagaatcta acatggaact ggaagaaagg     1680

aggaaaagag cagagcaact tcgcagagaa cttgaggaaa aagagcaaga acgcttggat     1740

attgaagaaa aatataccag tttgcaagag gaagcacagg gaaagaccaa gaagttaaag     1800

aaagtttgga ctatgctgat ggctgcaaag tcagagatgg ctgatctcca acaagaacat     1860

cagagggaaa ttgaaggcct actggagaac attcggcaac ttagccggga gcttcgactt     1920

cagatgctta ttattgataa ctttatacct cgggattatc aggaaatgat tgaaaactat     1980

gtccattgga atgaagacat aggagaatgg cagctaaaat gtgttgctta tacaggaaat     2040

aacatgagga agcaaacccc agtacctgat aaaaaggaga aagatccctt tgaggtggac     2100

ctttctcacg tgtatcttgc ctatactgag gagagtctgc gtcagtcttt gatgaaacta     2160

gaaagaccac gaacttcaaa ggggaaagca aggccaaaga cagggagaag aaagcgttct     2220

gcaaagcctg aaactgtaat tgactcttta ctgcagtaaa tgttacagac ttaaagtcac     2280

aataaaaatt agtgatattc tcatgcctgg acaaaatctt taattaaaac agtgaagact     2340

tctctataat ttcaattaat ggaagttgta gatcaatgaa taagactgga aataataatt     2400

tgcttaagaa cttttagtct acatatatta atataacatt aaaattgtac aactggtgat     2460

tgttcaaatt gttgtactac tactcttcaa ttgtactgtg cagggaagtt gggggaacag     2520

ttcatactat agagagttac agtttagatg tatgtgtaaa tcgattagct atttatccaa     2580

ctactgtata tttaggtaac tagaatttca aaatagaaaa aaaaaaactg tgtcctgttt     2640

tgcacataga aagaagcaga tcagattgtc ctatgttgcg ctgttatata tgaatgtttg     2700

gactgtacat ctaaagaatg attccgtcct aacacccacc cagcctgttt gaacacattc     2760

taattgtcta acatttgttg cattttaagt atgagatgac tgatcttatg aatgttttgt     2820

agaaaatgtt ataatttaac agtctttgcg agtatacatg ttttttaaca agttgaaaat     2880

gtttcatctg aacctttcct aacttttttt tgccagtttg agttcaaatc aaatacacct     2940

taagttctgg tttcatgttc tcttgaaaca ttgaattgta cgtaaatata aaggatctac     3000

tgttgcggaa aattaagaag ctaaatactg ctcagttatc tttgcctgcg tgtatatttt     3060

taaaaattca ctctgaagtg ttatggatgc ttttctttga gttctaaatt ttggtgggaa     3120

ttactttatg tctcccagtt aagaagagtc tccattttcc agaaaataca gctaagcaag     3180

aaaaatatct tttaaatact ttgcctttaa aacacttttt tattttgttt ttctatttta     3240

aaaataaaat attattttct gaatttcttc tattgggtaa tccagttaga ccatattcct     3300

ctacaaataa aaactatgtt gatttcatag taaagtaagt tgtaatagag ataattattt     3360

ttttctgttg ttagctgctt atgaaacttt tattgtattt ttttaaagtt atgctactcc     3420

tggccgggca tggtggctca cgcctgtaat cccagcactt tgggaggccg aggcacgtgg     3480

atcacttgat gtcaggagtt cgagaccagc ctggctaaca tggtgaaacc ctgtctccag     3540

tacaaataca ataattagct gggtgtggtg gcgcacacct gtaatcccag ctacttggga     3600

ggctgaggca ggagaatcac ttgaacctgg gaggcggagg ttgcagtgag ctgagatggc     3660

atcactgcac tccagcctgg gtgacagggt gacactccac ctcaaaaaat aaaaataaaa     3720

taaaaataaa gttatgctac tcctaaacca cttaatatat gttttgtggt tttcaaaatt     3780

atgtaatcag ccctgaaaca cattggttga aaatattttg agactttata agttagtatt     3840

tattaaatta atattatttt aataagtttt gttaaatcct agtttaaatg acaaagctgt     3900

gtatagagta ggggtgagtg aaggtggagt actcttgagg tggcgataaa aatgtaccca     3960

taaatttaaa gtccattctg taattggaat actgaatgtc ctgtgtgtgg tgaacatttt     4020

ctaggtgatt agaattgcat ttcactggct gcatttgttt gtggtatgta agatagctag     4080

aaatttatta cttaactctg tggggcattg tttagatact gtgaagagtt gaggtaaata     4140

tgtgtcttgt aaaagctttg tgtgatcaga atattttggt aattataaaa tgtttttgat     4200

gatacacatt taactctgtt agtaattact ctaaagaaat cttaatttta ccagtttaaa     4260

aaaaacgctt ctttttaaaa gttcatgttt ctaaccttta acaattcagt taataggaaa     4320

ggagtaactt ttaaatcaag ctttaaaaca tggaaattta agccagtatg ttagatattt     4380

tttctatccc accctaccat gataataaaa ataaatctat aaaaagtcaa aataaaaagc     4440

cgatctataa aaagtcaatt gagaagttct aaaagcaggc tactatagca ggggtgtttg     4500

ttttttgttt ggagacggag tctggctcta ttacctaggc tggagtgcag tgggacaatc     4560

tcggctcact gtaacctctg tctcttcagc ctcctgagtt gctggaacta cagctgtatg     4620

ccatcatgct cggctaattt ttgtattttt ttgtagagat ggggttttgc catgttgccc     4680

gggcctgtct tgaactccta gagcttaagt gatccacccg cctcaggctc ccgaagtgct     4740

gggattacag gcatgattat aggcctgagc caccacaccc cgcctactat agcagttttt     4800

taaaaaaagc attatgttaa aactgattat accagatgga cattaaatat ccatctcaga     4860

aataccaaaa tttgatacat aagcctggcc tgaatatctt tttttttttt ttgagacgga     4920

gtcttactct gtcgcccagg ctggagtgca gtggcgcgat ctcggctcac tgcaacctct     4980

gcctcctggg ttcaagggat tctcctgcct cagcctcttg agtagctggg attacaggtt     5040

tgcgccacca cacccagcta atttttgtat ttttttttta gtagagaccg ggtttcacca     5100

tgttggccag gctggtctca cctgactttg tgatccgccc gcctcagcct cccaaagtgc     5160

tgggattaca ggtgtgagcc accacgcctg gcctcaagcc tggtctgaat atctatatgc     5220

aaatatggga cactgacttc agagctattc atttagctcc agtcatagca attctgtagt     5280

ttcctcacat ttactgtgtc tttgtccaca aatgaaatat gttgtaaggt cagtgttaat     5340

ttcgtgagac gatatagatg aacacacttg ctcatttttt gaaataaata tgcagattta     5400

aaatgagtgg cacatatata taaataggtt attgaatggg tattctcttt tccctttaat     5460

ttaaaaagtg atatttattt attaaaagga gcattggtag aattattggt ttatagtatc     5520

ttctttaata atccttacaa ttacatatac taataggatg ttaaaattat catcgtgttt     5580

cctatttgtg tttagattct tataaagcat gagatgagta atcaagggaa gggtcgcatc     5640

tccatgtttg ccccatgaat agaatccatt tgacaagcca tttcatttcc tttctggaga     5700

aagggagttg tttttttttt ctttttacag caaaaattta aggttttatt gggggagggg     5760

gtggtgctac ttcctctgta acatgttttt aaaactatga ttatggtttt tggttgtttt     5820

ttgttttgtt tgtttccttt tagtctgttt ttaatatcct tccccttaac tcttaaggaa     5880

agtcttcttt cctacagggc tgtgaattaa ggaatgggta gcgtttacat ttaagtacac     5940

caatgtctgc ccaatttcct aatgtataca tttgttttat tttaaattat tttttgttct     6000

taaaaatact agaagaaaac atagatgttt ctagtgcctt tgaacttata ctgtagtctg     6060

actaatttaa tgaataactt cagtagcatt actataatac tgtatgctgg ccaaaattac     6120

aaattacagt ttgttgcatc agtttcaaaa gccatgcttt cattgtattt tatgtataaa     6180

ttgtatttgt tcaagttgta tatattggta ttgtatgtat acatgcagca tggttaaata     6240

agaataaaaa tcttttacct aatgccaaaa aaaaa                                6275


<210>  795
<211>  2729
<212>  DNA
<213>  homo sapiens

<400>  795
gaaggaagag gaagaggagg agagggaggc cagagccaga acagcccggc agcccgagct       60

tcgggggaga acggcctgag ccccgagcaa gttgcctcgg gagccctaat cctctcccgc      120

tggctcgccg agcggtcagt ggcgctcagc ggcggcgagg ctgaaatatg ataatcagaa      180

cagctgcgcc gcgcgccctg cagccaatgg gcgcggcgct cgcctgacgt ccccgcgcgc      240

tgcgtcagac caatggcgat ggagctgagt tggagcagag aagtttgagt aagagataag      300

gaagagaggt gcccgagccg cgccgagtct gccgccgccg cagcgcctcc gctccgccaa      360

ctccgccggc ttaaattgga ctcctagatc cgcgagggcg cggcgcagcc gagcagcggc      420

tctttcagca ttggcaaccc caggggccaa tatttcccac ttagccacag ctccagcatc      480

ctctctgtgg gctgttcacc aactgtacaa ccaccatttc actgtggaca ttactccctc      540

ttacagatat gggagacatg ggagatccac caaaaaaaaa acgtctgatt tccctatgtg      600

ttggttgcgg caatcagatt cacgatcagt atattctgag ggtttctccg gatttggaat      660

ggcatgcggc atgtttgaaa tgtgcggagt gtaatcagta tttggacgag agctgtacat      720

gctttgttag ggatgggaaa acctactgta aaagagatta tatcaggttg tacgggatca      780

aatgcgccaa gtgcagcatc ggcttcagca agaacgactt cgtgatgcgt gcccgctcca      840

aggtgtatca catcgagtgt ttccgctgtg tggcctgcag ccgccagctc atccctgggg      900

acgaatttgc gcttcgggag gacggtctct tctgccgagc agaccacgat gtggtggaga      960

gggccagtct aggcgctggc gacccgctca gtcccctgca tccagcgcgg ccactgcaaa     1020

tggcagcgga gcccatctcc gccaggcagc cagccctgcg gccccacgtc cacaagcagc     1080

cggagaagac cacccgcgtg cggactgtgc tgaacgagaa gcagctgcac accttgcgga     1140

cctgctacgc cgcaaacccg cggccagatg cgctcatgaa ggagcaactg gtagagatga     1200

cgggcctcag tccccgtgtg atccgggtct ggtttcaaaa caagcggtgc aaggacaaga     1260

agcgaagcat catgatgaag caactccagc agcagcagcc caatgacaaa actaatatcc     1320

aggggatgac aggaactccc atggtggctg ccagtccaga gagacacgac ggtggcttac     1380

aggctaaccc agtggaagta caaagttacc agccaccttg gaaagtactg agcgacttcg     1440

ccttgcagag tgacatagat cagcctgctt ttcagcaact ggtcaatttt tcagaaggag     1500

gaccgggctc taattccact ggcagtgaag tagcatcaat gtcctctcaa cttccagata     1560

cacctaacag catggtagcc agtcctattg aggcatgagg aacattcatt ctgtattttt     1620

tttccctgtt ggagaaagtg ggaaattata atgtcgaact ctgaaacaaa agtatttaac     1680

gacccagtca atgaaaactg aatcaagaaa tgaatgctcc atgaaatgca cgaagtctgt     1740

tttaatgaca aggtgatatg gtagcaacac tgtgaagaca atcatgggat tttactagaa     1800

ttaaacaaca aacaaaacgc aaaacccagt atatgctatt caatgatctt agaagtactg     1860

aaaaaaaaag acgtttttaa aacgtagagg atttatattc aaggatctca aagaaagcat     1920

tttcatttca ctgcacatct agagaaaaac aaaaatagaa aattttctag tccatcctaa     1980

tctgaatggt gctgtttcta tattggtcat tgccttgcca aacaggagct ccagcaaaag     2040

cgcaggaaga gagactggcc tccttggctg aaagagtcct ttcaggaagg tggagctgca     2100

ttggtttgat atgtttaaag ttgactttaa caaggggtta attgaaatcc tgggtctctt     2160

ggcctgtcct gtagctggtt tattttttac tttgccccct ccccactttt tttgagatcc     2220

atcctttatc aagaagtctg aagcgactat aaaggttttt gaattcagat ttaaaaacca     2280

acttataaag cattgcaaca aggttacctc tattttgcca caagcgtctc gggattgtgt     2340

ttgacttgtg tctgtccaag aacttttccc ccaaagatgt gtatagttat tggttaaaat     2400

gactgttttc tctctctatg gaaataaaaa ggaaaaaaaa aaaggaaact ttttttgttt     2460

gctcttgcat tgcaaaaatt ataaagtaat ttattattta ttgtcggaag acttgccact     2520

tttcatgtca tttgacattt tttgtttgct gaagtgaaaa aaaaagataa aggttgtacg     2580

gtggtctttg aattatatgt ctaattctat gtgttttgtc tttttcttaa atattatgtg     2640

aaatcaaagc gccatatgta gaattatatc ttcaggacta tttcactaat aaacatttgg     2700

catagataaa taaataaaaa aaaaaaaaa                                       2729


<210>  796
<211>  2427
<212>  DNA
<213>  homo sapiens

<400>  796
acttccgcca ggcggggacc cgatggccac ggtggctctg ggttgtcggg cctcgaaccg       60

ggtctccaga cgttgggccc ctccctccca gcgcgggaga ggcggggaag ggggcggggc      120

gggggagggg ccgcagcgct tttctccgga ggtcgcgcgc ccgagagccc gcgctgtccg      180

ccgccgctgc ctgagtcgac tctgcgccgc ccgccgcgat ggaggccgcc gcccagttct      240

tcgtcgagag cccggacgtg gtctacggcc ccgaggccat cgaggcgcaa tacgagtacc      300

ggacgacgcg cgtcagccgc gagggtggcg ttctcaaggt gcaccccacg tccacgcgct      360

tcaccttccg gaccgcccgg caggtgcccc ggctcggggt catgcttgtc ggctggggcg      420

ggaacaacgg ctccacactc accgccgcgg tgctggccaa tcgactgcgt ttgtcctggc      480

ccacgcgcag cggccgcaag gaggccaact actacggctc gctgactcag gcgggcaccg      540

tgagcctggg cctggacgcc gagggccagg aggtgttcgt acccttcagc gcggtgctgc      600

ccatggtggc gcccaacgac ctcgtgttcg atggctggga catctcgtcg ctgaacctgg      660

ccgaggcgat gcggcgcgcg aaggtgctgg actgggggct gcaggagcaa ctgtggccgc      720

acatggaggc cctgcggccc cggccttctg tttacatccc cgaattcatc gcggccaacc      780

agagcgcgcg cgcggacaac ctcatcccag gctcgcgtgc gcagcagctg gagcagatcc      840

gcagggacat ccgagacttc cggtctagcg cggggctgga caaagtcata gtgctgtgga      900

cggcgaacac ggagcgcttc tgtgaggtga ttccaggcct caacgacaca gccgagaacc      960

tgctgcgcac cattgagctc ggtctggagg tgtcgccctc cacgctcttc gccgtggcca     1020

gcatcctgga gggctgtgcc ttcctcaatg ggtctccgca gaacaccctg gtgcccggag     1080

ctcttgagct cgcgtggcag caccgggttt ttgtgggcgg agatgacttc aagtcaggcc     1140

agaccaaagt caagtccgtg cttgtggact tcctcattgg ctccggcctc aagaccatgt     1200

ccatcgtgag ttacaaccac ctgggcaaca acgatgggga gaacctatcg gcgccattgc     1260

agttccgctc taaggaggtg tccaagagca acgtggtgga cgacatggtg cagagcaacc     1320

cagtgctcta tacgcccggc gaagagcctg accactgcgt ggtcatcaag tatgtgccgt     1380

acgtgggtga cagcaagcgc gcgctggatg agtatacctc ggagctgatg ctgggcggaa     1440

ccaacacact ggtgctgcac aacacgtgtg aggactcgct gctggccgca cccatcatgc     1500

tggacctagc gctgctgacc gagctgtgcc agcgcgtgag cttctgcact gacatggacc     1560

ccgagccgca gaccttccac cccgtgctgt ccctgctcag cttcctcttc aaggcgccac     1620

tagtgccgcc cggcagcccg gtggtcaatg cgcttttccg ccagcgcagc tgcatcgaga     1680

acatcctcag ggcctgcgtg gggctcccgc cacagaacca catgctcctg gaacacaaaa     1740

tggagcgccc agggcccagc ctcaagcgag ttggacccgt ggctgccacc taccctatgt     1800

tgaacaagaa aggaccggta cccgctgcca ccaatggctg caccggtgat gccaatgggc     1860

atctgcaaga ggagccccca atgcccacca cctgaggccc cggtcacaca gtttctcggc     1920

tcttcctccc cgctgccccc cacgacccta ccttgaaggc ccccacaaat aaaggcgctg     1980

ccactcagcc ctccttccac ctggggttct tggggcctgt gacctgactc tgcctccctc     2040

tacttccccg actcttgagc gcccagcttc agtcccatcc cctctgccca tggtcatcac     2100

cccaactccc agggagagcc cagaacctgg agcctcgctc tgcccccagt tctcaaaggt     2160

ggggctagat gggggcgggg acggaacaag accacagggt ggagagtgtg gtggcagaag     2220

gccaaagagg gaatctgaga caagctacca aaaaccaaaa ccagcttcca tttatttatg     2280

ggccccaccc cctgacgtcc tggggagagg ggccccccaa agagcctttc tctctgggac     2340

aaaatacaaa tggcaggaag ggtccataca gaaaagaacg tctctgaggt ccttgcgttt     2400

ttaataaaat ggtaagagtc aaaaaaa                                         2427


<210>  797
<211>  10153
<212>  DNA
<213>  homo sapiens

<400>  797
gcacgggctg gtctctgccc taatgcggcg gctggcggcg agaggcgctg caggggacgc       60

gggggaagtg gcggcgccgg cagcggacag ctcggacagc gcccagggcc ggagcccgag      120

cccttggagg ttgattgact tatgtgcaat ttgggacgct ggagtttacc ttccctccgc      180

agcctggaac agagcctcct ctggtgttgc aaggaagagg ctgaatgagg cagagaagct      240

gagtgctgtc caggaggccc agttaaagcg gctcgaggtg acaagacccc gagtgctggg      300

gagcagggag cagggccagg tgccgaggat ggccaggcag ccaccgccgc cctgggtcca      360

tgcagccttc ctcctctgcc tcctcagtct tggcggagcc atcgaaattc ctatggatct      420

gacgcagccg ccaaccatca ccaagcagtc agcgaaggat cacatcgtgg acccccgtga      480

taacatcctg attgagtgtg aagcaaaagg gaaccctgcc cccagcttcc actggacacg      540

aaacagcaga ttcttcaaca tcgccaagga cccccgggtg tccatgagga ggaggtctgg      600

gaccctggtg attgacttcc gcagtggcgg gcggccggag gaatatgagg gggaatatca      660

gtgcttcgcc cgcaacaaat ttggcacggc cctgtccaat aggatccgcc tgcaggtgtc      720

taaatctcct ctgtggccca aggaaaacct agaccctgtc gtggtccaag agggcgctcc      780

tttgacgctc cagtgcaacc ccccgcctgg acttccatcc ccggtcatct tctggatgag      840

cagctccatg gagcccatca cccaagacaa acgtgtctct cagggccata acggagacct      900

atacttctcc aacgtgatgc tgcaggacat gcagaccgac tacagttgta acgcccgctt      960

ccacttcacc cacaccatcc agcagaagaa ccctttcacc ctcaaggtcc tcaccaacca     1020

cccttataat gactcgtcct taagaaacca ccctgacatg tacagtgccc gaggagttgc     1080

agaaagaaca ccaagcttca tgtatcccca gggcaccgcg agcagccaga tggtgcttcg     1140

tggcatggac ctcctgctgg aatgcatcgc ctccggggtc ccaacaccag acatcgcatg     1200

gtacaagaaa ggtggggacc tcccatctga taaggccaag tttgagaact ttaataaggc     1260

cctgcgtatc acaaatgtct ctgaggaaga ctccggggag tatttctgcc tggcctccaa     1320

caagatgggc agcatccggc acacgatctc ggtgagagta aaggctgctc cctactggct     1380

ggacgaaccc aagaacctta ttctggctcc tggcgaggat gggagactgg tgtgtcgagc     1440

caatggaaac cccaaaccca ctgtccagtg gatggtgaat ggggaacctt tgcaatcggc     1500

accacctaac ccaaaccgtg aggtggccgg agacaccatc atcttccggg acacccagat     1560

cagcagcagg gctgtgtacc agtgcaacac ctccaacgag catggctacc tgctggccaa     1620

cgcctttgtc agtgtgctgg atgtgccgcc tcggatgctg tcgccccgga accagctcat     1680

tcgagtgatt ctttacaacc ggacgcggct ggactgccct ttctttgggt ctcccatccc     1740

cacactgcga tggtttaaga atgggcaagg aagcaacctg gatggtggca actaccatgt     1800

ttatgagaac ggcagtctgg aaattaagat gatccgcaaa gaggaccagg gcatctacac     1860

ctgtgtcgcc accaacatcc tgggcaaagc tgaaaaccaa gtccgcctgg aggtcaaaga     1920

ccccaccagg atctaccgga tgcccgagga ccaggtggcc agaaggggca ccacggtgca     1980

gctggagtgt cgggtgaagc acgacccctc cctgaaactc accgtctcct ggctgaagga     2040

tgacgagccg ctctatattg gaaacaggat gaagaaggaa gacgactccc tgaccatctt     2100

tggggtggca gagcgggacc agggcagtta cacgtgtgtc gccagcaccg agctagacca     2160

agacctggcc aaggcctacc tcaccgtgct aggacggcca gaccggcccc gggacctgga     2220

gctgaccgac ctggccgaga ggagcgtgcg gctgacctgg atccccgggg atgctaacaa     2280

cagccccatc acagactacg tcgtccagtt tgaagaagac cagttccaac ctggggtctg     2340

gcatgaccat tccaagtacc ccggcagcgt taactcagcc gtcctccggc tgtccccgta     2400

tgtcaactac cagttccgtg tcattgccat caacgaggtt gggagcagcc accccagcct     2460

cccatccgag cgctaccgaa ccagtggagc accccccgag tccaatcctg gtgacgtgaa     2520

gggagagggg accagaaaga acaacatgga gatcacgtgg acgcccatga atgccacctc     2580

ggcctttggc cccaacctgc gctacattgt caagtggagg cggagagaga ctcgagaggc     2640

ctggaacaac gtcacagtgt ggggctctcg ctacgtggtg gggcagaccc cagtctacgt     2700

gccctatgag atccgagtcc aggctgaaaa tgacttcggg aagggccctg agccagagtc     2760

cgtcatcggt tactccggag aagattatcc cagggctgcg cccactgaag ttaaagtccg     2820

agtcatgaac agcacagcca tcagccttca gtggaaccgc gtctactccg acacggtcca     2880

gggccagctc agagagtacc gagcctacta ctggagggag agcagcttgc tgaagaacct     2940

gtgggtgtct cagaagagac agcaagccag cttccctggt gaccgcctcc gtggcgtggt     3000

gtcccgcctc ttcccctaca gtaactacaa gctggagatg gttgtggtca atgggagagg     3060

tgatgggcct cgcagtgaga ccaaggagtt caccaccccg gaaggagtac ccagtgcccc     3120

taggcgtttc cgagtccggc agcccaacct ggagacaatc aacctggaat gggatcatcc     3180

tgagcatcca aatgggatca tgattggata cactctcaaa tatgtggcct ttaacgggac     3240

caaagtagga aagcagatag tggaaaactt ctctcccaat cagaccaagt tcacggtgca     3300

aagaacggac cccgtgtcac gctaccgctt taccctcagc gccaggacgc aggtgggctc     3360

tggggaagcc gtcacagagg agtcaccagc acccccgaat gaagctactc caaccgcagc     3420

ttacaccaac aaccaagcgg acatcgccac ccagggctgg ttcattgggc ttatgtgcgc     3480

catcgccctc ctggtgctga tcctgctcat cgtctgtttc atcaagagga gtcgcggcgg     3540

caagtaccca gtacgagaaa agaaggatgt tccccttggc cctgaagacc ccaaggaaga     3600

ggatggctca tttgactata gtgatgagga caacaagccc ctgcagggca gtcagacatc     3660

tctggacggc accatcaagc agcaggagag tgacgacagc ctggtggact atggcgaggg     3720

tggcgagggt cagttcaatg aagacggctc cttcatcggc cagtacacgg tcaaaaagga     3780

caaggaggaa acagagggca acgaaagctc agaggccacg tcacctgtca atgctatcta     3840

ctctctggcc taacggagcc cacccaggca cagccaccac tttgcaagtg ggaggagggg     3900

agaaggggag acaaaaccac tgcagaccta ccacgaagcc accaccacct tcagtaacaa     3960

gggtacgata tgggggtctg ccaagctgtg aggaccagta gccaccaagc cacccacaag     4020

ccccctccca atgacccccc ttcagccccg ggtgccacca gtgtgggaga gctggagccg     4080

tggctgagct cagctggagg gagcctggcc ccttgcccgg tctcgcagcc accccgagcg     4140

ttccaccaca ctgtccgccc ttggcctcgg cacacgctca ccttttctgt tggttacggg     4200

acttctcatt gtcttaattt cgctttgtgc atcttcccct ccagacccaa tgtctctgtt     4260

ttcttttcct tttgaaaaag agtccctgga aaagaaagaa taagtggatt ctcccccagg     4320

agaatccttt ttgcaaagat aggcaaaaag gattgaatcc ataccagaac acgtagacag     4380

gctgtaatat tcaaaccacc tctgggccaa tgcatttcca aaggatgcct ttctcgccat     4440

atgcctcccc tggcccccag cccctctgcc tcggccttgt cagttgctga gctgggcttg     4500

gctcctttct ggaaaatgac agtatttttg gcagggagaa ggtgcgcagg cctccttgct     4560

gctctctggt ttggttggga ggtgtgttta cctcttgctc ctcattcctc ccctgccctt     4620

ttctctggaa tatctaagat gtgagctgca ttgactctga agacgtttga ggaacaggag     4680

tgggcactga tagaaaggac ttcaacgcca gtgactgtgt acctccagca gaagaaaatc     4740

aggtgtctgg tcttgggggc actgtgctca cttctagaga gaagaaaaag gctgggtttg     4800

gacttcatgc ctcctcactg gtgaaaccca ggatgtagat agagggccac acccaccctg     4860

tccagagtag agggcacctg tccacgtggc cagggcccat gctgccaccc tcgaggagat     4920

ggaaccctgt gatgcaaaag ctttgctggt gtgtttgggg cataaggcac tgctcccctt     4980

ccatctctag cagatatcat cttctcagcc aattctgtag gacactgagg ctcttgtttg     5040

acatggtgtg tggatgggga cttgccccaa gactgagcag gtctgccctt tcattggggt     5100

gtatacatat caggggaccc tgaggtggca ccgtactcag tgttgtgatg cccccaccta     5160

gggaggactc aatgctcttt gtatgcctta tgcagcgctg atctgtccct ggagttccca     5220

ggttcccagc tccccccctg caagccttga agcctccagc aacgtctatc tccaggagag     5280

cagggcagcc tatgcaagtg ttccggcagg accagaagtg gccactcaac acacgtcctc     5340

accagtcacc ccaaatggag acactcgcag acctgcagtt ctcagaccga aggtgctgcc     5400

ttcatcctcc ccacctaatg catttttgaa accaaaggta cctagcctca gagacagaga     5460

aggagagggg gagatcttga gtctaagagg aaccctttag ctgtttctgc agctgaggtc     5520

agtttcagga gggtgaagct gatccccagg aatggatcag ctgccatggg cacagcctcc     5580

gatttgagcc tctccggctg ccagccaggg ggcctgggcc agaccagggc tctgtccttc     5640

cgtgacttta ttaaagcaac atttgccaca tgtttaagcc gcaaaggtat tagcaatgct     5700

tgcatcatta ataatcattc agttgaaggt caagcccata gacacacact ctctgctggt     5760

aagaaaccat agcccagaac tgagccaata aggttgtttg aacctgagag tgtgtaatgg     5820

tcatttgggc caagcctcag ctagggctgc tgcctggacg cctgaggggc agcttatcac     5880

agtgcaaggg gacagggtaa acagcagggg gtggggtgtg agcttggagg gcccctcccc     5940

tggatttcct ccaacacctg cttggatact aggcccactg tccctgaagg gaatgtcagg     6000

gaagtgtgcc tgtgagctga attaaaggac tggcctttcc agaaaacgct ttggatctga     6060

gcagagtagt cagtttctca gacactcatt ccatactgca ccgtacatgc cagcgtaccc     6120

attgcaccga aagcaggccc ttagggcagg aagggacgat gagcaagtct gccacaccac     6180

ctggtgactg ggaagggctg cttctctcgt aagggtcttg gggagaagta agcccgcagc     6240

ctgcctctgc acctcgttcc agtgtcctgc caggctctgt actgtccttt gtgtatgaag     6300

aaaatgctgt tagccctctc tcaggctgct gttctgtggg tgctgagagc tgccccccat     6360

caccacgcca tcacacccct ctgagcagaa gcaaatctga ggctgaagaa ttaagttttc     6420

cccaagcaag gaaggcaggt ggtcagagag atcaaacgct gaggcgtggg gattgcagga     6480

ttcaggaggc agcccctttg gggaagagga gggtgcattt tccatggagc ccatgtcaga     6540

gtccactcca gctcagcagg aaagtggaat tgcccagtac tgcctgccag ctgggtctcc     6600

caagcaacta ccccaagaca taccaacagt gaagccagga cagcaccatg ccatcggcgc     6660

tccagtctgt ctggctggga ggaaagtgct gggcatctta cagtaactct agaagttcct     6720

ttgactaggc tgcaatccca cctatatgct cagccctaag agctgtggtt tcctgtgctc     6780

tcatttgtcc attcattcat tcattcattc attcagcaaa taatctgaaa tccagtctga     6840

actaaggcct gagctgtgga taccatggcg cgtgagttag atgtggtccc tgccctcatg     6900

gggctgacag tcctaaaatc aagtgctagg acacagtggc cattgagctg ggagcattct     6960

tccctctacc gcttaagcca ctgatggctg cgagcttgaa gagagggatt ctgagggaga     7020

gcttggtcca tctggtcacc aaggctgggc gggacagagc agtcaagaac cacggtgtgg     7080

cttgagaaac agtcctgctt cctgagcctc tttgctctgc ctcttggggc aagctcctta     7140

acctgtctgt atttttatgc ctctgtctcc cattcagttc ctccttgaat acctctttct     7200

acagagaggc acgggctccc ctgaaggatt gtcgaggcca gggttcggga agtacactgc     7260

catcggtcag gggacagctg cctcccacct tgcctgggtg atggtgaatg ggactcatct     7320

tttcctgcct tgcttttgag gagatggttg aatttaagct aacaggaaag ccaaaccagc     7380

accctccttt gtgctctgag aggttggaga catctggtcc accccattgc ccctgcccct     7440

ggcaagccct gaagtcggga gaggtgacca caggtctgaa aatcagccag tgccaacatt     7500

gcttgccctg caaggtgcaa ctgagcccac atagcgcatt catagtttcc ctgaccacag     7560

ccttgggaag acggtggaaa cccgaggatg tgtgggtttc ccagctaacg gacaagctcc     7620

cctgccacac ccagtgccca cgcatgctca catacataca gcagaccaca accctgttgc     7680

caagcagtgc ttccaaggga tagcgatcca gattccaaca ttgtcttgga gagggttagt     7740

ccacatccaa gttgcgtgag ataagatgca aagggctctg tgtggatgag gaacgcacct     7800

tagaggagtg ggaaaggcca ccagggttgg gccctgttta ggtaattcct gttggcagca     7860

cctagagaga gcatctgagc tgaaggagtg ggaaactttg cccaagcaat ggcacgggca     7920

gcgggctctt tctggcgccc tgtgctggag cagggccaag tcttagggca tcacaaacag     7980

cccatttgat ggagggagca gggacatagc acatttttgt ctgtctttgt gaggctgctt     8040

tgctaactct ctgaggagag gaagcctctc gggctttccg tcggctgggg ctagtgccag     8100

agaatccctt ctcagtggcc agcaggttcc tgggaggccg gcacaaggca ccgctcccca     8160

ctcatgacac cttggtgcag agtgacctcc tgcccagtca ccactccggc cagccccagc     8220

caaacacaca aaagcccatg gttgcggttg catctacacc gttagttggc aaaggatcct     8280

gcttgagctc tgcgtggtgg ccaaggagta gcatggagga gggccctgat tttaaaaagg     8340

aaaaatagag aggcctcaaa acaatgaaac aaagagcttg atatgtcaag aggagaccaa     8400

ggccctggga ggcataggca agccgggcag agtcagacca gtgccctccc ttgaccatct     8460

cctagcattc cttaacctag acaggggcta ccccatgtga gtccaagcca gactttgtgg     8520

ctgtccccag cctgcacagc ccaagcccag ggaagtgtcc tttctttccc ttccttacta     8580

ataatgggcc ttcctgagac acattcagag aaggatcaga gagaaaggag aaccatccag     8640

gagagccaca agcgtccacc aaacagtgtc tcaggcctca cctgaagctg ctgttcctcc     8700

tatcagcaca ctagtattaa atgggtgttc cataatgagg agaatggaaa taggtacaag     8760

gcatctagct taggacagaa tcggatttcg gcatgtgaag gaatcccaga gctgatctca     8820

ttgaaatgat ctatcgtaca gacaaggata tgcaaatcca cagaagtgaa gggatttttg     8880

ctcaagatca catagctggt aaactaaggt aaggttaggg cttgaacttg ggccttctga     8940

ctccttgtcc agtcagtgtt ctttcatctc accacagctg cctcctttga aacagaggta     9000

ttaagatctg tccttctggt tcaccctctc atacctcttt actgcgtctc ccacatcccc     9060

cacatgcctc ccaaaatgaa agacaaacag gattgtttct gagaccaaga tcagtctgtc     9120

tgtgatcagc ctgtgtgtgg ttcacccagt catgcaatta agggcagatc tgggccagtg     9180

gaataggata gctgattggt gtttgttact gtgaacccta gaccgtaccc cgtagaatgg     9240

tgtctcttgc tttgtaacac atcgggcctt cagtgtgctg tattcctcag aagtgagggc     9300

atctcggtcc attctgccca tggccacagg gtgcagagag gcagcagggc ccatgcaagc     9360

tgccaccctg ggatttgctg ggctggagtt caacagatgt aaagacttca gtgaagcaat     9420

aaacacaaaa ctctgggaga agatatccag aattttgtac attactctgt ttctttttca     9480

aaaatgaggc agatcagatg cccctgagct gccccttttt ttctgattcc caactgcaat     9540

gtcctcagtc agtgttgtcc ctctgcccgg ctccccagct ctttgccaac ctcttcacac     9600

tccccttgag ctgagcatca gtcgcctgtg acgtggccac cttctgtcct gctcccactc     9660

ccgacccatg ctggaccccg gaggacctcc tgccccgccc ccaccacaca cccatatccc     9720

ccaccattcc aatttgttct ttcccgtggg gaattttttt tcccagcgtc tccatccctt     9780

cctacatatc cacacacaca caaattggtc tgatcttttt tccattggtt aaacatttaa     9840

ctccatgcca gaccttgttt taacccctct cacatcatgt tctttccttt tttgcgagtt     9900

attttgcatt aaccaacttt gtcagtgaca gatgcgtatc tgagggtgtc acacacgacc     9960

ttcagcaggg aagacttctg ggccatggag ggccgtctaa tacatggact tataaactga    10020

ctgcatgagc aatgaaaagg ccaaattatt ctgaattttt tttgaatcac tgtaaaaaaa    10080

ctgatttctt ttgtatagag aacactaaac gtataataaa agttgttcaa aatggaaaaa    10140

aaaaaaaaaa aaa                                                       10153


<210>  798
<211>  3981
<212>  DNA
<213>  homo sapiens

<400>  798
aaagtgagtg agtgagacgg gcagatggag gagggattgt aatggcggca gccggcagct       60

ccctgctctg acccacggca ggcacacagc aacgacccct tccccgcccc tctcccggcc      120

ggcctccgcc ccgcagccag cgcggggcca ccctctccgg cccttccccc agctgtcggc      180

gtctcgccct gcgccccggc cggggcccca cacacaatgg acgagcttgc cggaggcggt      240

ggtggcggcc cggggatggc ggcccctccc cggcagcagc agggacctgg ggggaacctg      300

ggcctttcgc ccggggggaa cggagcggcg ggcggcgggg gtcctccggc ctccgaggga      360

gcgggtcccg cggcaggccc cgagctgtcc cggccgcagc agtacactat cccggggata      420

ctgcactaca tccagcacga gtgggctcgg ttcgagatgg agcgggcgca ctgggaggtg      480

gaacgggccg aactgcaggc ccggattgca tttctacaag gcgaaagaaa aggtcaagag      540

aacctgaaga aggacttagt aagaagaata aagatgttag agtatgcatt aaaacaagaa      600

agggcaaaat atcacaaatt aaaatatggc acggaactga accaaggtga cttgaaaatg      660

ccaacctttg agtcagaaga aaccaaagac acagaggctc ccacagcacc tcagaatagc      720

cagttaacgt ggaagcaagg cagacagctt ttaagacagt atcttcagga agtaggttat      780

acagatacaa tattagatgt acggtctcag cgggtaaggt cattacttgg actatctaat      840

tcagaaccaa atggatcagt agaaacaaag aatttagaac agatcctgaa tggaggtgaa      900

tctcctaagc aaaagggaca agaaataaaa aggtcctctg gtgatgttct tgagacgttc      960

aatttcttag aaaatgccga tgacagtgat gaagatgagg aaaatgacat gatcgaaggc     1020

atcccagaag gaaaagacaa acatcggatg aataaacata aaataggtaa tgaaggttta     1080

gctgctgacc taactgacga tcctgatact gaggaagcac tgaaagaatt tgatttttta     1140

gtgactgctg aagatggtga aggagctgga gaagcacgga gttcggggga tggcacagaa     1200

tgggctgaac caataacgtt tccatctgga ggaggcaagt catttattat gggttctgat     1260

gatgttttgt taagtgtact gggccttgga gaccttgcag acttgacggt aacaaatgat     1320

gcagactata gttatgattt gcctgctaat aaagatgcct ttcgaaagac atggaatccc     1380

aagtatacac tacgtagcca ttttgatgga gtacgggcat tagcttttca tcctgtagaa     1440

cctgtgctgg ttactgcttc tgaggaccat accctgaaac tttggaacct gcaaaaaaca     1500

gttcctgcca aaaagagtgc ctctttagat gtagagccta tctacacatt tagggcccac     1560

atcggccctg ttctgtcatt agctattagt tctaatggag aacagtgttt tagtggtggt     1620

attgatgcaa ccatccagtg gtggaatatg ccgagtccca gtgtagatcc atatgataca     1680

tatgagccaa atgttctagc tggcacttta gttggtcata cagatgcagt ttggggtctt     1740

gcttatagtg gcataaaaaa tcaattactg tcttgttcag cagatggcac tgttaggtta     1800

tggaatccac aagaaaaatt gccatgtatt tgcacttaca atggagataa aaagcatgga     1860

atacctacat cagttgactt tataggctgt gatccagctc atatggtaac ctctttcaac     1920

actggtagtg cagtaattta tgatttagaa acatcacagt cattggtgat actttcatca     1980

caggtagatt ctggtttaca atctaataat catatcaaca gagtagtaag tcatcccaca     2040

cttcctgtta caataactgc tcatgaagat agacacatca aattttttga caataaaacg     2100

ggtaaaatga tccattctat ggtagctcac ttggatgctg ttacaagtct agcagtagat     2160

cctaatggaa tctatttgat gtctggaagc catgactgtt ccatcagatt atggaattta     2220

gacagcaaga catgtgtgca agaaataaca gctcacagaa agaaattgga tgaatcaatt     2280

tatgatgttg ctttccactc gtcaaaagca tatatagcta gtgcaggagc tgatgctctt     2340

gccaaagtat ttgtatgaat caacaaaaac ttgcatcgta acaagatttg cttggacaga     2400

aagagggtct gcatcactgc catcagaaag gttactgata tgacactaca tgtgatctgc     2460

ctggtgaagg ctatctgggg caggcacaaa ttggtggaaa tcacatctta atgtcaagct     2520

cattaagtta actgtaatta ctgtattttg tgggacaaag aaaaaaggac tccagtattt     2580

gtggcctgta ctggatgtga actgagcgta tatctgtttt taggtgtctt taagccaatg     2640

tggagtctga tctttcaaaa aagttttttt ttttctcttc ttcttcttct tttttttttt     2700

tttttttttt tttttggact ctgtgtgctg ccttaggggt taggaatgtg gtgctcttgt     2760

tgggggaagt gagctccaag agtagctttt tttcatctct tagtgatctt ctgtttatcg     2820

gttgaatgcc acagattccc ttttaaactt attttgcttt aaaaaaaaaa aaaaagaaaa     2880

agaaaattta acttaaaata ttttagcatt agttgcacaa aatgtttgga taaaattcta     2940

gtttttataa gtctttttat atatttagcc tgtcacaaca gtgctcaaga ttgtattgaa     3000

gtttttctgc attatacaac cctaaaacac agagatctca ctgacccgtt gccctgtaac     3060

cactttcttt ccttcttttg cctaatacag ctcagctaag tccttccata aagatgctaa     3120

ataactttca tcatcacata aatgtcttca taaaccaagg actattaagt gtattaaaat     3180

gaaacagtgg ggtttagtac tccaaatgaa ctcttaaaga aaaaaactaa tcttggcatc     3240

ctatcactat gtgatatttt gtacatctta ctgtatttac aagtttattt atcaaggatt     3300

atccatcttg ctaatggcct attatttatt tcactttttg ttggtcttta tatcctttta     3360

ttaatgtgct aaaggaacct gtatatctat tttggaactc tttgaatagt ctaaaataga     3420

ctaaaaatgg agtattttat agtttaaatt acaaaccaag gtggttcccc ctaagatata     3480

tatcttggtt taccatgatt ccaaacaaaa ctaacttgtt taaaaatatt tggagtaaag     3540

ttttatttgc attacaaata ggatacaaaa atagttgaat caggatacag aaatctgctg     3600

tgttttgact agttatccct gttttatttt tttagatgtg cttaatttta tggtgtaact     3660

aaagattttg tttgtgtaat gcatgattaa gacaataaag tattttttct agtcttccga     3720

gaaacttttc tgatcagttt gcgagttttg atgagttttg taaggttttt gttttacaaa     3780

ctatgaatca gcaaattttt aagattgtac cacatagcaa acatacagct gttgaaaaat     3840

aatgtatata aaatgcatat aataaatatt aaattgtgta cctgtatgtt actgttggct     3900

acatcatttt gtgttgaata ataaagtgca atactttatt ctccataatt aaactaggaa     3960

atggagattt aaaaaaaaaa a                                               3981


<210>  799
<211>  2319
<212>  DNA
<213>  homo sapiens

<400>  799
ttccccactc ccccgccctc cccagggccc tgggaagggg ctcagcgtgg gaaaggatgg       60

ttgagtttta accagaggca aagcgtgagc gggatcagtg tgtgcggaac gcaagcagcc      120

gagagcggag aggcgccgct gtagttaact cctccctgcc cgccgcgccg accctcccca      180

ggaaccccca gggagccagc atgaagcgag ctcaccccga gtacagctcc tcggacagcg      240

agctggacga gaccatcgag gtggagaagg agagtgcgga cgagaatgga aacttgagtt      300

cggctctagg ttccatgtcc ccaactacat cttcccagat tttggccaga aaaagacgga      360

gaggaataat tgagaagcgc cgacgagacc ggatcaataa cagtttgtct gagctgagaa      420

ggctggtacc cagtgctttt gagaagcagg gatctgctaa gctagaaaaa gccgagatcc      480

tgcagatgac cgtggatcac ctgaaaatgc tgcatacggc aggagggaaa ggttactttg      540

acgcgcacgc ccttgctatg gactatcgga gtttgggatt tcgggaatgc ctggcagaag      600

ttgcgcgtta tctgagcatc attgaaggac tagatgcctc tgacccgctt cgagttcgac      660

tggtttcgca tctcaacaac tacgcttccc agcgggaagc cgcgagcggc gcccacgcgg      720

gcctcggaca cattccctgg gggaccgtct tcggacatca cccgcacatc gcgcacccgc      780

tgttgctgcc ccagaacggc cacgggaacg cgggcaccac ggcctcaccc acggaaccgc      840

accaccaggg caggctgggc tcggcacatc cggaggcgcc tgctttgcga gcgcccccta      900

gcggcagcct cggaccggtg ctccctgtgg tcacctccgc ctccaaactg tcgccgcctc      960

tgctctcctc agtggcctcc ctgtcggcct tccccttctc tttcggctcc ttccacttac     1020

tgtctcccaa tgcactgagc ccttcagcac ccacgcaggc tgcaaacctt ggcaagccct     1080

atagaccttg ggggacggag atcggagctt tttaaagaac tgatgtagaa tgagggaggg     1140

gaaagtttaa aatcccagct gggctggact gttgccaaca tcaccttaaa gtcgtcagta     1200

aaagtaaaaa ggaaaaaggt acactttcag ataatttttt ttttaaagac taaaggtttg     1260

ttggtttact tttatctttt ttaatgtttt tttcatcatg tcatgtatta gcagttttta     1320

aaaactagtt gttaaatttt gttcaagaca ttaaattgaa atagtgagta taagccaaca     1380

ctttgtgata ggtttgtact gtgcctaatt tactttgtaa accagaatga ttccgttttt     1440

gcctcaaaat ttggggaatc ttaacattta gtatttttgg tctgtttttc tccttgtata     1500

gttatggtct gtttttagaa ttaattttcc aaaccactat gcttaatgtt aacatgattc     1560

tgtttgttaa tattttgaca gattaaggtg ttgtataaat aatattcttt tggggggagg     1620

ggaactatat tgaattttat atttctgagc aaagcgttga caaatcagat gatcagcttt     1680

atccaagaaa gaagactagt aaattgtctg cctcctatag cagaaaggtg aatgtacaaa     1740

ctgttggtgg ccctgaatcc atctgaccag ctgctggtat ctgccaggac tggcagttct     1800

gatttagtta ggagagagcc gctgataggt taggtctcat ttggagtgtt ggtggaaagg     1860

aaactgaagg taattgaata gaatacgcct gcatttacca gccccagcaa cacaaagaat     1920

ttttaatcac acggatctca aattcacaaa tgttaacatg gataagtgat catggtgtgc     1980

gagtggtcaa ttgagtagta cagtggaaac tgttaaatgc ataacctaat tttcctggga     2040

ctgccatatt ttcttttaac tggaaatttt tatgtgagtt ttccttttgg tgcatggaac     2100

tgtggttgcc aaggtattta aaagggcttt cctgcctcct tctctttgat ttatttaatt     2160

tgatttgggc tataaaatat catttttcag gtttattctt ttagcaggtg tagttaaacg     2220

acctccactg aactgggttt gacctctgtt gtactgatgt gttgtgacta aataaaaaag     2280

aaagaacaaa gtaaaaaaaa aaaaaaaaaa aaaaaaaaa                            2319


<210>  800
<211>  3947
<212>  DNA
<213>  homo sapiens

<400>  800
gctcttcttc cttccttctc cagtcccttc cactgtgcgt cttctgtccc ccgttcttcc       60

ccagcggacc cctctttcga gactccctag tggggtcccc agctcccggg cgatcctgcc      120

cttgccgagc gcgttttctg gagtcacctg ggggagggga gtcctgggca gggccgggct      180

ggggaagacg cctggggcac tgcccggcgt taacaaaggg agccgatacc gaccggcgtg      240

ggcgcggagc gggcggccgc caccgagcgt gctgagcaac cgcagcctcc gcggccgaga      300

gtgcagcgag caaggggaga gccagttgcg cagagccctg caaccagcag tccagggaga      360

agtggtgaat gtcatggagc ccagctgaaa tggactggcc cccttgagcc tgtcccaagc      420

cctggtgcca ggtgtccatc cccgtgctga gatgagtttt gatcatcctg agaaaaatgg      480

gccttggcct gcagacccaa taaaccttcc ctcccatgga taatagtgct aattcctgag      540

gacctgaagg gcctgccgcc cctgggggat tagccagaag cagatgatca tgacgcagtc      600

ctgaggttta atggggcacc cacagccaac ttccaacaag atgtgggcac aaaaactacc      660

attcgcctga tgaactctca gttggttacc acagagaagc gcttcctcaa agacagtttg      720

tacaatgaag gaatcctaat tgtatgggac ccatctgtat accactcaga tatcccaaag      780

tggtaccaga atccggatta taatttcttt aacaactaca agacttatcg taagctgcac      840

cccaatcagc ccttttacat cctcaagccc cagatgcctt gggagctatg ggacattctt      900

caagaaatct ccccagaaga gattcagcca aaccccccat cctctgggat gcttggtatc      960

atcatcatga tgacgctgtg tgaccaggtg gatatttatg agttcctccc atccaagcgc     1020

aagactgacg tgtgctacta ctaccagaag ttcttcgata gtgcctgcac gatgggtgcc     1080

taccacccgc tgctctatga gaagaatttg gtgaagcatc tcaaccaggg cacagatgag     1140

gacatctacc tgcttggaaa agccacactg cctggcttcc ggaccattca ctgctaagca     1200

caggctcctc actcttctcc atcaggcatt aaatgaatgg tctcttggcc accccagcct     1260

gggaagaaca ttttcctgaa caattccagc ctgctccttt tactctaggg gcctctgtca     1320

gcaagaccat ggggacttca agagcctgtg gtcaggaaat caggtccagc cttccctgta     1380

gccagacagt ttatgagccc agagcctcct gccacacaca tgcacacata tctagcattc     1440

tttccagaca gcatcctccc cgccttccac cttggtagat gcaaggtcta tctctcccat     1500

cagggctgcc aaagctgggc tttgtttttc ccagcagaat gatgccattc tcacaaacca     1560

atgctctata ttgcttgaag tctgcatcta aatattgatt tcacgtttta aagaaattct     1620

cttaaattac aattgtgccc aatgcagggt ggctctgggg ggcaagtagg tggtacaggg     1680

gattggaaac atgctccgcg cctccagaga aaagttgctc ccgaggtcca tgcccctgga     1740

acgtgttcct atcactctgg ctggttgggc tggtccttag actgggtgct tatgattaaa     1800

gggtcttggt tagcccactt tccctctcca tgtggagatg gaaggtagag aaggatacag     1860

tgtctatcct caagttgcta cggttcagtg agagaggcag acatctgaac aggcaggtag     1920

gattcagtgt gctcagtgca ctggggattt ggagagagat gggcttgctc tctctgtgca     1980

cccaggaggg ccacgcactt aaaactgtgt ttgtggatca gagaaggctt tatagcacag     2040

ggggcattca gatgagtctt agaggaagag aagaaacatg gcaagcagat tacatctgag     2100

ccgtttgaat tgtgtttttc tttcttccca tgtttatttt ctaagatcta cctgaactta     2160

gagactcaag atattttttt aggaaacctc ctacccatgt ctgaggtagc aagtgcagcc     2220

tcacgacaga taccaggcaa tccagagcca caaaacgtga ttcctccagg ctctgcctgg     2280

cctgaccctg tcctgtcagc tgggtttaca taccagtccc attcttcctt ttcaatacct     2340

acccccaaat cttctcctaa ccaccatctg tttttttttt ttaaagcatt ttttgcttta     2400

aaagcatcct gaccccaatt tctttgagct cacgggcctt ttgctgaagg tctctcaggg     2460

tgtagtggtg tggctctctg gacttaacgt cactctcaga ggtcagaacc ttggagatca     2520

gaactgattc tcaccaggtg tgagaggtgt ggtagcagat tgcaatgctc tgcacctctt     2580

ccttgcaagt gagcaacttc aggctctctg ggcagaggct ggcccactgt agtttgcaga     2640

catgctctcc agatggtttt actaagtccc ctctccctga tagggaatcc tgctggacca     2700

gcgcagccct ggtgtggaga ggttaaaaga cttgcacagg atcaccaagt catgctgtag     2760

agccaggatt cctagaccca gggctctgca ctctcaaggc tggccccatg tgctcaaggg     2820

gatctaatgt ttgggctcca aactaaccat ctcggagctg ggctcctcat ttactgccaa     2880

accctcagct tatgtagcta gaaagggccc tggagtgaga aagcctggat tttcaaattg     2940

atgctcccct actgactagc tgtgccactc tgggcaaatg ctcttccttg agcctgtttc     3000

cacacctgta aagtggggat gatgatccta tctcactgct tttgtgagga ttacaggaaa     3060

gcacctgtcc tggctctgta cctggcacgt agtaggtgct cagttcatgc tggtttcctt     3120

cctgccttta gtagggacct gctctgtgct cacacctcgg ctgcatgcac cctgctgtga     3180

cggaggctag tgtggaagag gtcctgtcct cagggaatta actgtcttat tgggagacaa     3240

caactgtcct ccttggaaca cccaagaaac catgcaaagc agtggacaac acagaacacg     3300

ccctcctcct cgctgcctgc agctccaatc tgattctgct tgggaatggg cggagcacgt     3360

gggctgctta actgctgtat aggacaagcc ccttacccct ctctgggccc atgaattcct     3420

ggcttggttt atgttctgat ttgacacact gattttaatc ttcgaatcat gacactgagt     3480

gcagaggagg tggcattccg acagcaggac atacatgttg gtgtgaagac tgggacgaca     3540

ctgggtagaa tctagttttt aattattatt aatataaagg atcaaattaa tttaaatatg     3600

attctgaagt ctacagaact tttagttctg tgctgtctat gtggacactt tggtaaaatg     3660

caaattatga tatggacgtt atcattggtc tggtgagatg tttcatattt gtgacagtta     3720

atttaaaaat tatgagttaa tgctgcctgt gtctatgggg ttctgtcttc tttgatagcc     3780

atctattcat ctggatcatg ggaccctctc taatccttcc accaatcaaa taagctattg     3840

ctattggttt ggagttgaga tatcagtctc ggaaacttct gaaaaatgct aataattacc     3900

caaggattat gtcaaatttt aaaataaatg tgtgtgtgtt tctttaa                   3947


<210>  801
<211>  2599
<212>  DNA
<213>  homo sapiens

<400>  801
gaaaagactc ggggttccga gggccgcaga ccgctagccc tacgtcactt ccgcttcctt       60

tcccgcaggg cgggtaattc gaacgttttt tgcagcgagt ggccttcccg gttggcgcgc      120

gcccggggcg gcggcgctgg aggagctcga gacggagcct aagttatgtc tgggaggcga      180

acgcggtccg gaggagccgc tcagcgctcc gggccaaggg ccccatctcc tactaagcct      240

ctgcggaggt cccagcggaa atcaggctct gaactcccga gcatcctccc tgaaatctgg      300

ccgaagacac ccagtgcggc tgcagtcaga aagcccatcg tcttaaagag gatcgtggcc      360

catgctgtag aggtcccagc tgtccaatca cctcgcagga gccctaggat ttcctttttc      420

ttggagaaag aaaacgagcc ccctggcagg gagcttacta aggaggacct tttcaagaca      480

cacagcgtcc ctgccacccc caccagcact cctgtgccga accctgaggc cgagtccagc      540

tccaaggaag gagagctgga cgccagagac ttggaaatgt ctaagaaagt caggcgttcc      600

tacagccggc tggagaccct gggctctgcc tctacctcca ccccaggccg ccggtcctgc      660

tttggcttcg aggggctgct gggggcagaa gacttgtccg gagtctcgcc agtggtgtgc      720

tccaaactca ccgaggtccc cagggtttgt gcaaagccct gggccccaga catgactctc      780

cctggaatct ccccaccacc cgagaaacag aaacgtaaga agaagaaaat gccagagatc      840

ttgaaaacgg agctggatga gtgggctgcg gccatgaatg ccgagtttga agctgctgag      900

cagtttgatc tcctggttga atgagatgca gtggggggtg cacctggcca gactctccct      960

cctgtcctgt acatagccac ctccctgtgg agaggacact tagggtcccc tcccctggtc     1020

ttgttacctg tgtgtgtgct ggtgctgcgc atgaggactg tctgcctttg agggcttggg     1080

cagcagcggc agccatcttg gttttaggaa atggggccgc ctggcccagc cactcactgg     1140

tgtcctgtct cttgtcgtcc tgtccttcct atctccccaa agtaccatag ccagtttcca     1200

gatgggccac agactgggga ggagaatcag tggcccagcc agaagttaaa gggctgaggg     1260

ttgaggtgag aggcacctct gctcttgttg ggaggggtgg ctgcttggaa ataggcccag     1320

gggctctgcc agcctcggcc tctccctcct gagttgcctt ctgttggtgg ctttcttctt     1380

gaacccacct gtgtaaagag gttttcagtt ccgtgggttt cccctttgat tctgtaaata     1440

gtcccagaga gaattcgtgg gctgagggca attctgtctt ggaggaagaa gctggacatt     1500

cagcctgtgg agtctgagtt ttgaaggatg tagggagcct tagttgggtc tcagaccata     1560

agtgtgtact acacagaagc tgtgttttct agttctggtc tgctgttgag atgtttggta     1620

aatgccaggt tgatagggcg ctggctgctt ggagcaaagg gtgcatttca gggtgtggcc     1680

accaggtgct gtgagtttct gtggctcatg gcctctgggc tggtcccttg cacagggccc     1740

acgctggagt cttaccactc tgctgcaggg gtggaaggtg gcccctcttg tcacccatac     1800

ccatttctta caaaataagt tacaccgagt ctacttggcc ctagaagaga aagttgaaga     1860

gtcccagacc tactagcatt ttgcaactat gcttgtaaag tcctcggaaa gtttcctcgc     1920

gtaccagaca gcggcggggg ctgatagcaa ttttagtttt tggcctccct atcctctcac     1980

atgagaacac tgcctggatg catctcatga tctctggaga atttccccat ctttctcttc     2040

tttccatcgt gtggattcaa tagtgtggat ttgaaggctg ccctgccccc gactctcctg     2100

ccgcacccct ggccattgta ccttttgatg tttagaagtt cgtggaagta gacgctgagg     2160

tgtgcagagg agctggtgga taacagagaa tgccagggaa gatgagtgct gggtcagggt     2220

acttggatga aacggtgcag gccaggcggg ccctaataaa accctctgcc aggtctggga     2280

gtcccaggcc atctgctcaa cgctctgtgg tttgtcagac ctgcaagcaa gccccctgct     2340

ggggaagcct aggtgtcctt gagctgaacc gcactgaaga actcttgtcc tcactggctg     2400

atgcagcaga actcttggga aatgtcttag tcctgcagaa tcaggagtca ccagatgatg     2460

cagagttgag atcatcattg caaagttctc tgttcctgag gaactaaatt taaggaaaaa     2520

atgggatttt gttttagagt tggaaaaaaa gcctgattaa agagtttctg cctgttaaaa     2580

aaaaaaaaaa aaaaaaaaa                                                  2599


<210>  802
<211>  7333
<212>  DNA
<213>  homo sapiens

<400>  802
ggcggcggcg gcggcgcgga ctgggtgcgc ggcgcagcgt cctgtgttgg aatgtgcggc       60

tgccgcgagc tcgcggcgca gcagcggagc gagcgccgcc gaggcccggg gccccagacc      120

ctggcggcgg ctgccgcagc cgagacggca gggcgaggcc cggaggcctg agcaccctct      180

gcagccccac tcctgggcct tcttggtcca cgacggcccc agcacccaac tttaccaccc      240

tcccccacct ctcccccgaa actccagcaa caaagaaaag tagtcggaga aggagcggcg      300

actcagggtc gcccgcccct cctcaccgag gaaggccgaa tacagttatg gccacccagg      360

taatggggca gtcttctgga ggaggagggc tgtttaccag cagtggcaac attggaatgg      420

ccctgcctaa cgacatgtat gacttgcatg acctttccaa agctgaactg gccgcacctc      480

agcttattat gctggcaaat gtggccttaa ctggggaagt aaatggcagc tgctgtgatt      540

acctggtcgg tgaagaaaga cagatggcag aactgatgcc ggttggggat aacaactttt      600

cagatagtga agaaggagaa ggacttgaag agtctgctga tataaaaggt gaacctcatg      660

gactggaaaa catggaactg agaagtttgg aactcagcgt cgtagaacct cagcctgtat      720

ttgaggcatc aggtgctcca gatatttaca gttcaaataa agatcttccc cctgaaacac      780

ctggagcgga ggacaaaggc aagagctcga agaccaaacc ctttcgctgt aagccatgcc      840

aatatgaagc agaatctgaa gaacagtttg tgcatcacat cagagttcac agtgctaaga      900

aattttttgt ggaagagagt gcagagaagc aggcaaaagc cagggaatct ggctcttcca      960

ctgcagaaga gggagatttc tccaagggcc ccattcgctg tgaccgctgc ggctacaata     1020

ctaatcgata tgatcactat acagcacacc tgaaacacca caccagagct ggggataatg     1080

agcgagtcta caagtgtatc atttgcacat acacaacagt gagcgagtat cactggagga     1140

aacatttaag aaaccatttt ccaaggaaag tatacacatg tggaaaatgc aactattttt     1200

cagacagaaa aaacaattat gttcagcatg ttagaactca tacaggagaa cgcccatata     1260

aatgtgaact ttgtccttac tcaagttctc agaagactca tctaactaga catatgcgta     1320

ctcattcagg tgagaagcca tttaaatgtg atcagtgcag ttatgtggcc tctaatcaac     1380

atgaagtaac ccgccatgca agacaggttc acaatgggcc taaacctctt aattgcccac     1440

actgtgatta caaaacagca gatagaagca acttcaaaaa acatgtagag ctacatgtga     1500

acccacggca gttcaattgc cctgtatgtg actatgcagc ttccaagaag tgtaatctac     1560

agtatcactt caaatctaag catcctactt gtcctaataa aacaatggat gtctcaaaag     1620

tgaaactaaa gaaaaccaaa aaacgagagg ctgacttgcc tgataatatt accaatgaaa     1680

aaacagaaat agaacaaaca aaaataaaag gggatgtggc tggaaagaaa aatgaaaagt     1740

ccgtcaaagc agagaaaaga gatgtctcaa aagagaaaaa gccttctaat aatgtgtcag     1800

tgatccaggt gactaccaga actcgaaaat cagtaacaga ggtgaaagag atggatgtgc     1860

atacaggaag caattcagaa aaattcagta aaactaagaa aagcaaaagg aagctggaag     1920

ttgacagcca ttctttacat ggtcctgtga atgatgagga atcttcaaca aaaaagaaaa     1980

agaaggtaga aagcaaatcc aaaaataata gtcaggaagt gccaaagggt gacagcaaag     2040

tggaggagaa taaaaagcaa aatacttgca tgaaaaaaag tacaaagaag aaaactctga     2100

aaaataaatc aagtaagaaa agcagtaagc ctcctcagaa ggaacctgtt gagaagggat     2160

ctgctcagat ggaccctcct cagatggggc ctgctcccac agaggcggtt cagaaggggc     2220

ccgttcaggt ggagccgcca cctcccatgg agcatgctca gatggagggt gcccagatac     2280

ggcctgctcc tgacgagcct gttcagatgg aggtggttca ggaggggcct gctcagaagg     2340

agctgctgcc tcccgtggag cctgctcaga tggtgggtgc ccaaattgta cttgctcaca     2400

tggagctgcc tcctcccatg gagactgctc agacggaggt tgcccaaatg gggcctgctc     2460

ccatggaacc tgctcagatg gaggttgccc aggtagaatc tgctcccatg caggtggtcc     2520

agaaggagcc tgttcagatg gagctgtctc ctcccatgga ggtggtccag aaggagcctg     2580

ttcagataga gctgtctcct cccatggagg tggtccagaa ggaacctgtt aagatagagc     2640

tgtctcctcc catagaggtg gtccagaagg agcctgttca gatggagttg tctcctccca     2700

tgggggtggt tcagaaggag cctgctcaga gggagccacc tcctcccaga gagcctcccc     2760

ttcacatgga gccaatttcc aaaaagcctc ctctccgaaa agataaaaag gaaaagtcta     2820

acatgcagag tgaaagggca cggaaggagc aagtccttat tgaagttggc ttagtgcctg     2880

ttaaagatag ctggcttcta aaggaaagtg taagcacaga ggatctctca ccaccatcac     2940

caccactgcc aaaggaaaat ttaagagaag aggcatcagg agaccaaaaa ttactcaaca     3000

caggtgaagg aaataaagaa gcccctcttc agaaagtagg agcagaagag gcagatgaga     3060

gcctacctgg tcttgctgct aatatcaacg aatctaccca tatttcatcc tctggacaaa     3120

acttgaatac gccagagggt gaaactttaa atggtaaaca tcagactgac agtatagttt     3180

gtgaaatgaa aatggacact gatcagaaca caagagagaa tctcactggt ataaattcaa     3240

cagttgaaga accagtttca ccaatgcttc ccccttcagc agtagaagaa cgtgaagcag     3300

tgtccaaaac tgcactggca tcacctcctg ctacaatggc agcaaatgag tctcaggaaa     3360

ttgatgaaga tgaaggcatc cacagccatg aaggaagtga cctaagtgac aacatgtcag     3420

agggtagtga tgattctgga ttgcatgggg ctcggccagt tccacaagaa tctagcagaa     3480

aaaatgcaaa ggaagccttg gcagtcaaag cggctaaggg agattttgtt tgtatcttct     3540

gtgatcgttc tttcagaaag ggaaaagatt acagcaaaca cctcaatcgc catttggtta     3600

atgtgtacta tcttgaagaa gcagctcaag ggcaggagta atgaaacttt gaacaaggtt     3660

tcagttctta gtttgtaagg tatattacat tttatattca tttatgatag cagacaacct     3720

tttaagattg ctttaattag tatctgatgt tgatttttaa gtggcattct tttccttagg     3780

actttttatg tatacctgtt gattgttgtg taaattttag taaatctaag agagtgtact     3840

aaaccagcag gtatctgtta gcttatgtgt ttaattgaaa ttagaaggct aagatggtat     3900

aacagcattt tattgctttg tccagctaca acttgtcatt tttttctcca tgtcttatct     3960

tcctgtttca ctttagttta ttcttcgttt tttattgaga tctataaaaa attggcttac     4020

ttaatagcaa attacttgaa gaatttgcct gctttatata aagttagcac tttaagattt     4080

ttttttttag agatgagaag acatttaaat tgaagaaaaa ttcccccagc aatagacagt     4140

ctatcagtcc aagtatttac ttcctgagtt ttgatcaata ttttttattt gtgtatgtta     4200

atcgtcataa aaacagtgat tttggtgtgt tttttatttt ggtgctttaa tggcttaaga     4260

tgttgcacat tttttttttc ttttggtttc tgtttatgtt tttttgccta tgcagttaaa     4320

tttttcctag aaatagcatt tgtgttgaac agtaacactt tatacatata tatatgcatg     4380

tttattttgt ttggcgtctt tggagggatg cttttagact tgtttgcaaa agggcagttt     4440

tctttttctt tgctgcagtt gtctattttg cagaataata gtgtgtgcaa gtttgtgagc     4500

aaatgaaata tgcaggttca atctattgat tttgattttt acatcttata tctatgccag     4560

aatctgtatt tcatataact tatttatttc gaatggatgt agtaaattca cagctatcag     4620

ttttgatttt gcaataaata aaccactagg ttgcatgtcg aacaaatttt tatctcaaat     4680

accaaccatc agtttttttt ttcatgtgtt ttggtacagc taattcctaa ttgtagagtg     4740

ttaaatgttt gaggagaacc ttttctcata gatggttggt gttcatatgg ctactttaca     4800

ataaagagaa ctgtaagtga tatttggaaa ctacaaacct ggaattagga gatataatta     4860

ttccttcaag ttttatagaa tatcacttgg gagattccaa agccatagct attacgcggc     4920

aaacctagga taagaaaggt agtatgagtg ctggtagacc agctgcaact ttcctataca     4980

gtgaaaaagg ctggtgaaac aagtacagtc cagatttttt aaaatcatac tttctcaggg     5040

atctccacaa actggtgggt gtcctggctg tctgtgtgat agcctctttc tataggtgag     5100

gcctcaaatg aattgcagct atcctggtgt tcctatgagg gcactttgta tgaaaaaggg     5160

catgtactcc aaaacatttt tgtaggttct ttggccagtt gccaaagagt gtgaaagaat     5220

ccaatagagg atttttctta ctgatagcag tcattcattg cagtaaaata aaatatgatc     5280

ccattaggga atcttgaatt ctgacctccc atactccgtt ttgaaataac cactttatat     5340

ttcatttttt aaaaatctga tgatctcttt gaggcaggtt tcagatttgg cagtacaaca     5400

tgaaagatta ggaaaagcat taataacgtg tgggtggaaa gcttgttaaa aatctgagag     5460

tgaagtttga gttaaaagtt gtttgaacat ggcattgact gggaggccaa agatttaaag     5520

aagcggaaga ttcttctctt aagacatgag gagtaagttg tgtgataatg gtatgtgttt     5580

tgtgtgcatg aatggacatt gtaaatgttg aattctaggc tccgacaatc attgtcaaca     5640

gaagatcaag ctgcaaatat ttatgtttta aaacttaaat tataaagcta gttaagtctt     5700

tctaatgact agttttaatg ttcatgggta cattttacct aagttaccgt ttacattgta     5760

tagaaaaaga tacatcttaa gcacagattg gttattagga attagtttgg ggaagaggtt     5820

tttttgtgga ttctttcata ctgcaaagaa aaaccatttg ccttttgggg aattgagcta     5880

acttctaatc tagtcttaag actagaatgc taaaaacaaa aacatgaagg aaattaaaac     5940

cccttattat taaattgatt tgtaaaaaca ttgttactgg aaatttattg gacttgaggc     6000

cttcctccag aaaataagga cttgattgtc aggcctatat taggttctga accttaatgc     6060

catgtatttg tacttactaa aaattgtttc aatgaaaagt acattagcag tatgaacttc     6120

tggtccagtt ggaagttttt ccatttgaaa aatgtgatgt ttgcatggaa ctgtttgaaa     6180

cttttttatt ttctagtccc cctcccccac actggataga atttagccta gaattttccc     6240

tttggataaa agaacaaaaa ttgaacatgt tatttgtaaa ttgatgttta gtaattagtg     6300

ataaacttga aatactagca tatattataa gccttaatct taggtagtct tatgaaaatg     6360

aatctcttaa ctatcttttg aacctgtatt cacattggtt ttcaagatat tttaagttat     6420

attttttcct cttttcagag ctgcttctta ttctggggct actttttttt ttagttgtgt     6480

aattcacaaa gggctgcatt tttttttttt tttaataagg cttataacta tggctggatc     6540

ttttgctcta gtcttctaag aagggccatt ttatttttta gagtcacttc taaagtcatg     6600

tggtaattaa ctttggagac tgttttgcgt atgagtgctg atacaaatta aaacccaagt     6660

agacctcatt gcatgtcacc ctatgaatgt tgacaatgga aggaatacct tgcctgtagt     6720

atactgtcac ttctggattg ataagctgag gaagaaagtt aagtttcttt tttacataag     6780

tcagaaaaac ttacagctgg tgttcctagt ttcctggttg acctcagcag atgaagtgaa     6840

cagatagtgt taattcagat tgaagaaatt atctgaatct tggtttgtgt agatttacaa     6900

tctacatgca atattaacta aatcagatag cttttacagt ttcacatgtg tacataggtt     6960

ccctcccggt cccttccata tccattagtt attgaacttt ctaaactggc attgaaacat     7020

tacaacaatg ttttgttgca ccaattttat aaacttaagc agtgcaatac gtgttacttt     7080

tctgaggcaa accaaaggta aatttctcaa ggttcttgct gccttcttta gcagcatttg     7140

atggaagatc ttttatacat ttgtaataga taaaaataaa ccagattgca aatccttttt     7200

taaaatccta aaccatgtac caagtttttg gtccaaatta tgtaggataa gttaaactta     7260

aattgcattc tattaaccaa tatgagtgta tttctgtaag catagttatg ttgaaataaa     7320

gttttaaaaa cca                                                        7333


<210>  803
<211>  2544
<212>  DNA
<213>  homo sapiens

<400>  803
ggactgacct accgaccatt cttccgggtc cagaaggtga tctccgcccg tgctcagaat       60

ccaggggccc ggggctgtag attccttgac aaggatatcc tagcggcgaa acaacaccgt      120

actgggagtc agaacgtctg ggttctagtc ttgactgcca ttaactagcg gtatgacatt      180

ggagaagctt ttttgaccct tctggatttc cgtttccttt tctgtaaaat gaggagcttg      240

gaagatccgg aaaatgaggc ccataggaaa caagtgactt gctgagtcca gataacactg      300

actgtcagag agaaacatga accagaagct actgaagttg gagaacttgc tacgatttca      360

cactatttat aggcaactgc acagtctgtg tcaaagaaga gcattaagac agtggaggca      420

tgggttttca tctgcttacc ctgtgtggac agctcaactg tgtgcctggc cctggccaac      480

agatgtgctc actggggctg ctttatctca gtataggctt ctagtaacaa aaaaggaaga      540

aggaccatgg aaatctcagt tatcttcaac aaaatctaaa aaggtggtag aagtatggat      600

tggaatgact attgaggaac tggccagggc aatggaaaaa aacacagatt atgtatatga      660

agctttattg aacactgata ttgacataga ttcactggaa gcagactcac atttagatga      720

agtctggatc aaagaagtga taacgaaggc agggatgaag ttaaagtgga gtaaattaaa      780

acaggacaaa gtcagaaaaa ataaagatgc tgtaagaagg ccccaggcag atccagcttt      840

attaacccca aggtccccag ttgttactat aatgggccat gttgatcacg ggaaaacgac      900

attacttgac aaatttcgaa aaactcaagt ggcagcagtg gaaactggag gcatcactca      960

gcacattggt gcctttcttg tctctctgcc ttctggggaa aagataactt ttcttgatac     1020

tccaggacat gctgctttct cagcaatgag agccagaggt gctcaggtca ctgacattgt     1080

cgtattggtt gtagctgcag atgatggagt gatgaaacaa actgtagaat ctattcagca     1140

tgccaaagat gcacaggttc ctattatcct tgccgtaaat aaatgtgaca aagctgaggc     1200

tgatcctgag aaagtgaaaa aagagctgct ggcttacgat gtggtatgtg aagattatgg     1260

aggtgatgtt caagcagtgc ctgtctccgc acttacgggc gataatctga tggctttggc     1320

agaagcaaca gttgctcttg cagaaatgtt agaattgaaa gcagatccca atggtccagt     1380

ggaaggaaca gtaatagagt ctttcacaga caaaggaaga ggtcttgtta ctacagctat     1440

aattcaaaga ggaactttaa gaaaaggctc tgttctggtt gctggaaaat gttgggcaaa     1500

agtacgctta atgtttgatg aaaatggaaa aacaattgat gaggcctatc ccagcatgcc     1560

agtgggaatt acaggctgga gagaccttcc ttctgcagga gaagaaattc ttgaagtaga     1620

atctgagcca agggcacgtg aagttgttga ctggaggaaa tatgaacaag aacaggagaa     1680

aggtcaggag gatctgaaaa taatagaaga aaagcgaaag gaacacaaag aagcacatca     1740

gaaagcccgt gagaagtatg gccatctact gtggaagaag agatcaattc tacggttttt     1800

agaaagaaaa gaacaaatac ccttaaagcc aaaagagaaa agggaaagag attcaaatgt     1860

actttctgtg attattaaag gtgatgttga tggttctgtt gaggccattt tgaacattat     1920

agatacctat gatgcttcac acgagtgtga actagaatta gtacattttg gagtgggtga     1980

tgtaagtgca aatgatgtta accttgctga aacatttgat ggtgttatat atggctttaa     2040

tgtgaatgca ggcaatgtta tccaacagtc agctgcaaaa aaaggagtaa aaattaaact     2100

tcacaaaata atttaccgtc ttgttgaaga tttgcaagag gaactgagca gcagattacc     2160

ctgtgctgtg gaagagcacc cagtaggtga ggcatctata ctagctacct tctctgtaac     2220

agaagggaag aaaaaagttc ctgtggctgg ctgcagagtc caaaagggac agttagaaaa     2280

acaaaaaaaa tttaaactaa cccgtaatgg acatgtaatt tggaagggct cattaacctc     2340

attgaaacac cataaagatg acatttcaat tgtcaaaacg ggaatggatt gtggtctcag     2400

tttagatgaa gacaatatgg aatttcaagt gggagacaga attgtttgtt atgaagaaaa     2460

gcaaattcaa gccaagactt cttgggatcc aggattttaa aattacatta aaaatgtaaa     2520

taactcaaaa aaaaaaaaaa aaaa                                            2544


<210>  804
<211>  1910
<212>  DNA
<213>  homo sapiens

<400>  804
cttccccggc tggggcggct ggagagccgg gagtcgctgg gtgcgtgggg ctgcctcgcc       60

gcgtctcgcc acgggctctg ccagcagaca gccttggcac acaggcacaa gggctggagc      120

ccagagatga gagtgcccaa gggagatgtg agcctggcgg gctgcccgct aacctgtcgc      180

tgaagcccca gaagcgggcc ctcaggccag gcctaccctg cctccggccc agcatgcgcc      240

tgtcggtgcg gagggtgctg ctggcagccg gctgcgccct ggtcctggtg ctggcggttc      300

agctgggaca gcaggtgcta gagtgccggg cggtgctggc gggcctgcgg agcccccggg      360

gggccatgcg gcctgagcag gaggagctgg tgatggtggg caccaaccac gtggaatacc      420

gctatggcaa ggccatgccg ctcatcttcg tgggtggcgt gcctcgcagt ggcaccacgt      480

tgatgcgcgc catgctggac gcgcaccccg aggtgcgctg cggcgaggag acccgcatca      540

tcccgcgcgt gctggccatg cgccaggcct ggtccaagtc tggccgtgag aagctgcggc      600

tggatgaggc gggggtgacg gatgaggtgc tggacgccgc catgcaggcc ttcatcctgg      660

aggtgattgc caagcacgga gagccggccc gcgtgctctg caacaaggac ccatttacgc      720

tcaagtcctc ggtctacctg tcgcgcctgt tccccaactc caagttcctg ctgatggtgc      780

gggacggccg ggcctccgtg cactccatga tcacgcgcaa agtcaccatt gcgggctttg      840

acctcagcag ctaccgtgac tgcctcacca agtggaacaa ggccatcgag gtgatgtacg      900

cccagtgcat ggaggtaggc aaggagaagt gcctgcctgt gtactacgag cagctggtgc      960

tgcaccccag gcgctcactc aagctcatcc tcgacttcct cggcatcgcc tggagcgacg     1020

ctgtcctcca ccatgaagac ctcattggca agcccggtgg tgtctccctg tccaagatcg     1080

agcggtccac ggaccaggtc atcaagcctg ttaacctgga agcgctctcc aagtggactg     1140

gccacatccc tggggatgtg gtgcgggaca tggcccagat cgcccccatg ctggctcagc     1200

tcggctatga cccttatgca aaccccccca actatggcaa ccctgacccc ttcgtcatca     1260

acaacacaca gcgggtcttg aaaggggact ataaaacacc agccaatctg aaaggatatt     1320

ttcaggtgaa ccagaacagc acctcctccc acttaggaag ctcgtgattt ccagatctcc     1380

gcaaatgact tcattgccaa gaagagaaga aaatgcattt aagtggaaat cggacctcta     1440

atccaagcat attgcttgct attaatcgcc aaaacaggac tgctgatgag gaatgtattt     1500

gcatatgttt gcaaaagctg aatcattgaa aacgtacctt gaaactctct atctctggac     1560

actccagggt agagaatgaa gggtatggaa gtagtccggc ttttgaaact taggtatttt     1620

atatttttcc cctcaagaac ttttttttaa gagacagatt tgccatcctc cttaatttgc     1680

aggactgcct tggtggcttt gtttgctggg acaaggccca caacctgtgc ctctcctatt     1740

gacccttact ttgaattcaa agaatctatt taagagttta atatatgagg ctttctttga     1800

ttcctcctca gttctaccta gtttcacaga ggaaaaaaat actctttgaa taaagtgaac     1860

agaggctcat ttgtttgtgc cttactttac tgaaaaaaaa aaaaaaaaaa                1910


<210>  805
<211>  1310
<212>  DNA
<213>  homo sapiens

<400>  805
catttgggga cgctctcagc tctcggcgca cggcccagct tccttcaaaa tgtctactgt       60

tcacgaaatc ctgtgcaagc tcagcttgga gggtgatcac tctacacccc caagtgcata      120

tgggtctgtc aaagcctaca ctaactttga tgctgagcgg gatgctttga acattgaaac      180

agccatcaag accaaaggtg tggatgaggt caccattgtc aacattgtga ccaaccgcga      240

caatgcacag agacaggata ttgtcttctc ctaccagaga aggaccaaaa aggaacttgc      300

atcagcactg aagtcagcct tatctggcca cctggagacg gtgattttgg gcctattgaa      360

gacacctgct cagtatgacg cttctgagct aaaagcttcc atgaaggggc taggaaccga      420

cgaggactct ctcattgaga tcatctgctc cagaaccaac caggagctgc aggaaattaa      480

cagagtctac aaggaaatgt acaagactga tctggagaag gacattattt cggacacatc      540

tggtgacttc cgcaagctga tggttgccct ggcaaagggt agaagagcag aggatggctc      600

tgtcattgat tatgaactga ttgaccaaga tgcccaggat ctctatgacg ctggagtgaa      660

gaggaaagga actgatgttc ccaagtggat cagcatcatg accgagcgga gcgtgcccca      720

cctccagaaa gtatttgata ggtacaagag ttacagccct tatgacatgt tggaaagcat      780

caggaaagag gttaaaggag acctggaaaa tgctttcctg aacctggtcc agcgcattca      840

gaacaagccc ttgtattttg ctgatcagct gtacgactcc atgaagggca aggggacgcg      900

agataaggtc ctgatcagaa tcatggtctc ccgcagtgaa gtggacatgt tgaaaattag      960

gtctgaattc aagagaaagt acggcaagtc cctgtactat tacatccagc aagacactaa     1020

gggcgactac cagaaagcgc tgctgtacct gtgtggtgga gacgactgaa gcccgacaca     1080

gcctgagcgt ccagaaatgg tgctcaccat gcttccagct aacaggtcta ctaaacatac     1140

aaaagtttag ccgggcgtgg tggcgctcgc ctgtagtccc agctagtccg gaggctgagg     1200

caggagaatg gcttgaaccc ggaaggcaga ggttacagtg agccgagatc atgccactgc     1260

actccagcct gggcaacaga gctagactct gtctctaaat aaataaataa                1310


<210>  806
<211>  1376
<212>  DNA
<213>  homo sapiens

<400>  806
gcaggaccgt cattgacgcc atgagcgcgc tgctgcggct gctgcgcacg ggtgccccag       60

ccgctgcgtg cctgcggttg gggaccagtg cagggaccgg gtcgcgccgt gctatggccc      120

tgtaccacac tgaggagcgc ggccagccct gctcgcagaa ttaccgcctc ttctttaaga      180

atgtaactgg tcactacatt tccccctttc atgatattcc tctgaaggtg aactctaaag      240

agattctttc ttgtggagaa gttattcatg tgaagatcct tggaattttg gctcttattg      300

atgaaggtga aacagattgg aaattaattg ctatcaatgc gaatgatcct gaagcctcaa      360

agtttcatga tattgatgat gttaagaagt tcaaaccggg ttacctggaa gctactctta      420

attggtttag attatataag gtaccagatg gaaaaccaga aaaccagttt gcttttaatg      480

gagaattcaa aaacaaggct tttgctcttg aagttattaa atccactcat caatgttgga      540

aagcattgct tatgaagaag tgtaatggag gagctataaa ttgcacaaac gtgcagatat      600

ctgatagccc tttccgttgc actcaagagg aagcaagatc attagttgaa tcggtatcat      660

cttcaccaaa taaagaaagt aatgaagaag agcaagtgtg gcacttcctt ggcaagtgat      720

tgaaacatct gaaattctgc tgtcaagatt cccatctcta aggactccaa gtgctagaga      780

caagggggtc tatgagcatt tactgacttc ctgttaaaac ttcatttttt caaacttttt      840

gagctatgca atatataaat aaacagtaag aattttaaat tactctcctt tggacattta      900

ttgatataaa aagaagattt tggccaggca cggtggctca tgcctgtaat ttcagcactt      960

tgggaggccg aggtgggcag atcacaaggt caggagttca agaccagcct ggccagtatg     1020

ttgaaacccc atctctatta aaaatacaaa aattagccag gcgtggtggt gcatgcctgt     1080

agacccagct actcaggagg ctgaggcaga agaactgctt gagcccagga ggcagaggtt     1140

gcagtgagca gagattgtgc cactgcactc cagcctaggc gacagagaga gactccgtct     1200

caaaaaaaaa aaaaagattt tgtttcattt catagcacaa atttagaggc attgagttga     1260

ccatttctag tttctatacc tgaaggaacc cattgatttt accagttttt atttctgtag     1320

attggatgta aaaatcacag attcaataaa ttaataaact ttgtgtaaaa aaaaaa         1376


<210>  807
<211>  5888
<212>  DNA
<213>  homo sapiens

<400>  807
gagctggctg agagcgagag catgcctgga ttcttctgag gcatcaggaa aagcgttttg       60

catatttttc attgcctttc tttttttttt ttttttttta acttttgcct cagaaagaca      120

gctccctttc agagcaggaa tttcccttca aggtagcagg agatgaacgc gtgctgctcc      180

aggattttac agaactgatt ctgcagcaaa gacaaatgtt gcctgtattt gccagatagt      240

ataaacagga gcaaaagttg cacagctaaa ccaggggctc attcccagga cagacatgca      300

gttatggatt ccgaaagaca agtcaaggac actgatgaca ttgaaagtcc taaacgcagt      360

atccgagaca gtggctacat cgactgctgg gattccgagc gcagcgactc cctctctcct      420

cctcgccacg gcagagatga ttccttcgac agcctggatt cctttggctc tcgctctcgg      480

cagacgcctt caccagatgt agtcctcagg ggaagcagcg atgggagagg aagcgactct      540

gaatccgact tgcctcatcg gaagctgcca gatgtgaaga aggatgacat gtctgcacgg      600

cggacttccc atggtgagcc gaaatcagca gtgcctttta accagtacct cccgaacaaa      660

agcaatcaga cggcctacgt ccccgcgcct ctgagaaaga agaaagcaga gagagaggaa      720

taccgcaaga gctggagtac cgccacctcc ccgctgggtg gggagaggcc cttcagatac      780

ggtccgagaa ctcctgtgtc tgatgacgca gagagcacca gcatgtttga catgcggtgt      840

gaggaggagg ccgcggtgca gccgcacagc agggcccgcc aggagcagct gcagctgata      900

aataaccagc tgagggaaga ggacgacaaa tggcaagatg acctggctcg ttggaagagt      960

cgtagaagaa gtgtttctca ggacttaatc aagaaagagg aagaaaggaa aaaaatggag     1020

aagttactgg ctggagaaga tgggacaagt gaacgaagga aaagcatcaa aacctacaga     1080

gaaattgttc aagaaaaaga gcggagagag agagagctgc atgaagcata taagaacgct     1140

cggtcccagg aggaggcaga ggggatcctt caacagtaca ttgagaggtt caccatcagt     1200

gaggctgttc tcgaacgctt ggagatgcca aaaattctgg aaagaagcca ttcaacagag     1260

ccaaatttat cctccttcct gaatgacccc aatcccatga aatacctgcg gcaacagtca     1320

ctgcctccac ccaaattcac tgccactgtt gaaaccacca ttgctcgtgc cagtgttctg     1380

gataccagca tgtcagcagg cagtgggtct ccaagcaaaa ctgtcactcc caaagcagtg     1440

cctatgctga cacccaagcc ttactcccag cccaaaaatt ctcaagatgt tctgaagacc     1500

tttaaggtag acgggaaagt cagtgtgaat ggagagacgg ttcatagaga ggaggagaag     1560

gaaagagagt gtcccacggt ggcacctgcc cactccttaa ccaaatccca gatgtttgaa     1620

ggtgtggcca gagtgcacgg gtctccactg gagctgaaac aagacaacgg tagcatcgag     1680

atcaacataa agaagccaaa ctctgttccc caagagctcg cagcaaccac tgagaaaacg     1740

gaaccgaata gtcaagagga caagaatgat ggtggaaaat caagaaaagg gaatatagaa     1800

cttgcctcat cagaaccaca gcattttaca acaactgtga ctcgatgcag cccgaccgtg     1860

gcctttgtgg aatttccctc cagcccccag ctgaagaatg atgtgtcgga agaaaaagac     1920

cagaagaaac cagaaaatga aatgagtgga aaggtggagt tggtgctgtc acaaaaggtg     1980

gtaaagccaa aatctccaga acccgaagca acgctgacat ttccatttct ggacaaaatg     2040

cctgaagcca accaactaca tttgccaaat ctcaattctc aagtggattc tccaagcagt     2100

gagaagtcac ctgttatgac accttttaag ttctgggcat gggacccaga agaggagcgc     2160

aggcgacagg aaaaatggca acaggaacag gaacgtttgc tccaggagag ataccagaag     2220

gagcaggaca agctgaaaga agagtgggaa aaggcccaaa aggaggtgga agaggaagaa     2280

cgcagatact atgaggagga gcgtaagata attgaagaca ctgtggttcc atttactgtt     2340

tcttcaagtt ccgctgacca gctgtctacc tcttcctcca tgactgaagg cagtgggaca     2400

atgaataaga tagacctggg aaactgtcaa gatgaaaaac aagacagaag atggaagaaa     2460

tcattccagg gagatgacag tgacttattg ctgaagacta gggaaagtga tcgactggag     2520

gagaagggca gcctaactga aggggccttg gctcattctg ggaaccctgt atcaaaagga     2580

gtccatgaag accatcagct ggataccgag gctggggccc cacactgtgg aacaaaccca     2640

cagcttgctc aggatccatc ccagaatcag cagacatcaa atccaacgca cagttcagaa     2700

gatgtgaagc caaaaaccct cccgctggat aaaagcatta accatcagat cgagtctccc     2760

agtgaaaggc ggaagtctat aagtggaaag aagctgtgct cttcctgtgg gcttcctttg     2820

ggtaaaggag ctgcaatgat catcgagacc ctcaatctct attttcacat ccagtgtttc     2880

aggtgtggaa tttgtaaagg ccagcttgga gatgcagtga gtgggacgga tgttaggatt     2940

cgaaatggtc tcctgaactg taatgattgc tacatgcgat ccagaagtgc cgggcagcct     3000

acaacattgt gacacggctt tcaagcttcc ggatcactca ccatttcttt actgagagtg     3060

tcccctggca actgcttaac aaaatcccaa gctcaggggc ttctcagcat ttacctaatt     3120

tctgaaaggc tcttctgaaa ggtggtatct gttctttcgt agcacagtgt ttatgttttt     3180

cctgtttatt gttttggttt tttttttttt tttgcatttg cacagtatac acaaaagaat     3240

atggggttgt aatgatcctg aatagctcaa aaaaggtttt agcatggtca aacaggctta     3300

tggtttaaaa tgtgttattc tcttctttgg gaattagcta aatgatgcaa taaacctgtt     3360

ttgttttaga atgtctagga attaaacact ttatgtttac agaattgagc tgcagaaagt     3420

gcaagacatg ccaatttgag acacacggtc ttctaagact gaaggataaa tttaatgcat     3480

ttcagaaact aaacatcaca gcaagctcta tctctgagct ataatttgtt tttaatgcaa     3540

agacactagt ttgataatat atactgtaat cctgaaacat ttgtgttact tacctttgga     3600

ggtagaaatt ataccaataa attattgcac cgttagtatt agattctgtg taccttggaa     3660

gttatgtcat taatataggc tggttcatca aataaagcaa aaccttgcaa tatcagctag     3720

atttacactc cgggacgttg cccaaaggta ggaagaaagc agagggaaat atttcagtca     3780

tcatttccaa agtcattatc aaaatctgtg aggaagttta atcttccaaa gagtcaatgt     3840

cagacatcag gcctctgttg cctgcttctc tcgaggcact agattaggag tcttcaataa     3900

gagacttaac atgaggtata tggaagatga ggcaccgaga taagttcatc attaggtgtg     3960

agcactgctc acccttgctg gcaagttctc cttaagggcc tgaagcacag gtgtccaaag     4020

aaaagcgtta agtccatctt aatagaatct atgtggtata tgatgtggtc agcccctggt     4080

ctgtgatcag caagaaccta cagcacagat tatgccctgc ccacttcaat gaatacctac     4140

tctcctccat tctccatcac tttttttgct atcaagaact ccggaccttg cccatggaga     4200

agtttagaga ggaactcttg tggagagctg gtttattttc tgccctgtgc gacgagtttc     4260

agctggccaa gaaaggagtc aagttattaa aaagcatcac aatgtagatc tccaggctgg     4320

ttttttgttt tttgttgtta agactgggga aagggggact atttattctg ccttaaatca     4380

atggcaaata agtcaagatg acattttgtg aatgtagact atggatacac tcctaataga     4440

ttgatgtagt cataaaaggg ggtcaagtag atgtttttct gttatgtaag caataatttt     4500

tccgtgtctt attgagtatg gctagcgatt atttattaca tgctagatgg gttctttgca     4560

tgtgggttcc atataggtgc agaaatttcc tcagccactg gagggatttc gaccatattt     4620

gtcatttgga tgagctgtta ttagattgaa atctacacat catttcatta aaaattgtgc     4680

cttagaaaac gcaaagctgt tgcacatggc gataaattat ggatgcagta cattgaagag     4740

agatgaagtc acttccaagt ttccaagact tctcatggag gtgtttgctg ttttacagga     4800

aaaaataaaa ataaaaaaag aaaaaaagaa aaaattaaaa agaaaaattg ttttgaaaat     4860

gtacagatca agtccaatat tttgattatc cacctgcatg ttttattaaa tattttgata     4920

atgtggatgt ttacactttg catgatatta gcagagtacc actagtaatg cacaaacatg     4980

tacaatatgg tcattcataa ccgattttta tagaatactt tttacatgtg caactccatc     5040

cgttatgtaa ggattacatg aatattgcac attcccttct ggtttcacaa acccatttat     5100

acatatttct tagtgaggct cattgtacat gtattgaagc tagaatcgag tcaagaaaaa     5160

taaagcccca ttctccaact gcaaaatgtg ctttcccata atgaacacta gtcaccagca     5220

cagaataatc tccaacattt tctaaattct aattgccaac tgtttctatt tatatttgat     5280

ttatatttca tttggagtct gttacatggc agcttaggca gactagatct tgttttttcc     5340

aatgcagcat aatgagtatg atctatttct tttcaaataa tctttgagat cccaggaaaa     5400

aaaaaatgct ctgctccatt gagctataat gtaaatgtgt ttgtttaaaa aacaggtgag     5460

gcaagtgagt gatttattgt tcctgaggaa gtatatctga ttttttttct catactccaa     5520

aagctagtcc ctactcttta ataaaaataa tgggtaactt tttgtttttc actagcgaac     5580

ttccatgaca tttcctttct atgtagtgtg attaatgcaa tacatattat agttatctat     5640

acacagtgta agatttaaca aactgaaatg atccacctca tatgtgagtc cgtccaaaag     5700

atgttactgc tctgggtggg ccagtgttct atatcggtta tactaacttt catttaaagt     5760

atttattcta aaatgcctct gagaaacagt aaaaaataaa aacaacaagt tgtctaaaat     5820

gcaacagctt ttatagtaaa tgtacattta taaataaaat actcaaatca aaaaaaaaaa     5880

aaaaaaaa                                                              5888


<210>  808
<211>  5770
<212>  DNA
<213>  homo sapiens

<400>  808
ttctctttgc tgaggcttac ttgtccagcc tattgtttga gacaacagat ataagttgcg       60

atgggagagg agcgtcggat ttggtgtgta tcccccattt ccaattatag atggatcatt      120

acagacagcg gagtcctgag aagccagaca tctgctcctc acatgaatgc actcacctcc      180

tagagaccag gctgccatca tgctctggaa gcttgtggag aatgtcaagt acgaagatat      240

ctatgaggac cggcacgatg gtgtcccgag ccacagctcg cggctctccc agctgggctc      300

ggtgtcccaa ggaccctact cgagcgcccc gccgctgtcc cacaccccgt cgtcggactt      360

ccagccgccc tacttcccac ccccctacca gccgctcccc taccaccaga gccaggaccc      420

ctactcccac gtcaacgacc cctactccct gaacccactg caccagcccc agcaacatcc      480

ctgggggcaa cggcagcggc aagaagtggg ttcggaagcc ggctctctcc tgccccagcc      540

tcgggccgcc ttgccccagc tctcgggcct tgacccccgg agggactacc actcggtccg      600

ccggccggac gtgctgctgc attcggcgca ccacggcctg gacgcgggca tgggtgacag      660

cctctcgctg cacggcctcg gccatcccgg aatggaagac gtccagtcag ttgaagatgc      720

caataacagc ggcatgaatc tattggacca gtctgtcatt aaaaaagttc cagttcctcc      780

caaatcggtg acttctctaa tgatgaataa agacggcttc ctgggaggca tgtctgtcaa      840

caccggcgag gtgttttgct ccgtcccagg ccgtttgtct ctgctcagtt caacttcgaa      900

gtacaaagta actgtgggag aagttcagag acggctgtcg ccccctgaat gcctcaatgc      960

atctctcctc ggcggagtcc tcagaagagc caaatcgaaa aatgggggga gatctttgcg     1020

agaaaggcta gaaaaaatcg gtttgaattt acccgcgggc aggcgcaaag cagcaaatgt     1080

cacgttactc acctccctgg tggaaggaga agctgttcac ttagctaggg attttgggta     1140

catttgcgaa acggagtttc ccgccaaagc cgtctctgag tatttgaacc ggcagcacac     1200

agacccgagt gacctgcact cccgaaagaa tatgctgttg gccaccaagc aactttgtaa     1260

agaatttacg gatctactgg cgcaggaccg gacaccgata gggaacagcc gacccagccc     1320

catcctggag ccggggatcc agagctgcct cacgcacttc agcctcatca cgcacggctt     1380

cggcgccccg gccatttgcg ccgcgctcac ggccctgcag aactatctca ccgaggcgct     1440

caaaggcatg gacaagatgt tcttgaacaa caccaccact aacaggcaca cgtctgggga     1500

aggcccaggt agtaaaactg gcgacaagga ggagaaacac aggaaatgaa aaatttttaa     1560

aaaaagaagg aaaaatgttt taaatacaaa aggaaaaaca gacaaaaatt taattttagc     1620

tttaaaatat tggattggct ttggaagaat tatattaggt agaatacaca tacaatcaaa     1680

attttaaaaa aaaaagctaa ataacttaaa aaaaaactga ggcgtacaac ggagcaacaa     1740

tatcggttct cagtgtctat ttcaagatac atttggagac aaccgtccgg attttccact     1800

tcggttcttt cgagtttagt aatactgata ataaaagaaa accatgattt ccccttccct     1860

ttggaaaata aacataagac taaacatgag aaaaacgcta acttattgga agaaaatcgg     1920

agaaacgttg gtgtcaatgc tttgagagct ggttgactga gacgcacgaa ctttttaatt     1980

ttaaatatat ttttaggaaa ctctcgcagt ccccgccctc catctcacct cacccgtctc     2040

ccaaccaccc ttttccatgt taccctccct tcctcacatt gttacgggaa tcttctggga     2100

tgaaaatgag tgtggttggc ccttttgcgt tgtttcagtc ctctcggtac ctccccgccc     2160

agccctgcga tcttaactca ccgggcccgg ctccccggcc gcttgcataa ttagggaggg     2220

cgagggcggg gcgggaggcc tgtggagacc aggcggaggc tgcaattttt ggtgccggcc     2280

ggcagagcag gttctggcgg ctgaggaaaa tccggaccaa taagttgatt caaacatcat     2340

cagttccttt cagaaatgtt actagctccc agccttgcca gcatctgcat agagagaatc     2400

tcacatttat tatatttgtg tcatctacta attttatgaa ctatagtaaa aaaaaaaaaa     2460

cacacacaca cacaatatga atacgttgat tagtatgtaa ttccttcgga ggggtatgta     2520

ccatttcatt ctcttctgtt ttccaaagct ttgcccgcat ggtttatgag cttcttcaaa     2580

gaggacttgg gcttcctaca caatctataa ggtacagaga aaaaaaaatc cgatcccttt     2640

ttaatcaaag cctgtgtgtc agaattctgc aggtgcactt ctttaaagaa gctcaaaggg     2700

aataatttag aaagtggcca atatgatgga agcagctttg aatctacatg ctaacattcc     2760

tcaacactcc aattccggtg gaggtggcag gggagggggt ctgcaaaatg aattttaagg     2820

gaaaagagta aggattctta gagccctata ttctaatagt attgccctgc atttaaaatt     2880

gatttgattt ccctgggttc tttggtgatt gctgtttaag caaggaaaga agcagcttta     2940

cgagtggacg tggggaggag ggcggcacaa gcacccacat ttctgtaaca attgctttct     3000

tacaagatgc tttatgaatg aggcattttt ccctcccaga cgtgcacttg ttttggcata     3060

taatggcaaa ataatgcaaa gtgaagggag atgtatttca gctttgattt ttaccgtctg     3120

gatacatcgg gactattccc agtggataaa gtttcatgca tttaatattt ctcacttctg     3180

gcagcccagc tcctttcttg ggctccatct tagcattatc atgaaataag atctggaatc     3240

cattgtctgc acctccgcaa aagcagtgag aaattatccc gggataaggg tgaatgagag     3300

aggtctctaa atatagtgtt gatacactca cctatttaac aaagtagacg agatctttgc     3360

aatacccctt aaagataacg acatagatgt tgttctgcag gatttatagt taggacccac     3420

tcaattctcc aggactcccg gttttgcccc cctcccgctt tgccttggtg ggggtgggga     3480

ttgggggagt ggggattgcg ttggggtttt aggaatctgc tgagagcttt gcccattttt     3540

attaaaagag gaaagggaag ttaggaagct cgtctcaggt caccaaaagg gcccaagcaa     3600

ctgttagggc cacactgcag cccatctcca acccctagct tcgtttagca cttctgatct     3660

tcatggccca gccctagaac tgttgagagg aatgcaatgg ccaagagcta gacgttacgg     3720

agagtgtagt cactctcttt tcccagctca gaggcctgcg ccttcgtccg agagctcggc     3780

cgatcgcatt agatgtgttc tgattgcaca aggccaggag agaccacact gaaaacgatc     3840

gtctcctttc cttgcagggc aacgcgcccc acgcgtgtga cgtgcgagag acgcgatgga     3900

cgcgccttgc tcttactgtg caggtcctga gagcgtgtgg gccacaggcg cccagtcgtg     3960

ttgaggacat agaatcagcc gctggagggg ctgccgactg cgcgggccct tcccgctctc     4020

ggtctcaccc taagggctaa ggcgaccgag aaagccccat tctccagtag gtaatggggc     4080

ggcgcccggt gggctgcagg tggggagggc tcccagcgcc gccagcggcc acccggggcg     4140

ccggctcctg gagggagagt ggcctagaaa tatccaagga atccgaagct tcccctcctc     4200

cacctctgcc agtacggaaa caccccaccg tcacaatcct aaagcgggga gatgggatgg     4260

gaattgtctt acttggcaag gcagggtacc ttcattgcca gacgccctca tttgtgtgtt     4320

cctccttgct ccagcgagat agaacctttt gcgcccccaa ccccgtttcg tggagtgagc     4380

ccactacccc ttctccctcc ctcacttctc ctttcatgta ggacccccgc ccccttgctt     4440

tccttagcca ggcccgctac atttatctga taattgagtt attaaaagat ttggtttcct     4500

tgggcctata aatcaataaa cagtaggatt aacgcaatag tttgcctttt aagtcaaggg     4560

agacgtttaa ggcaagcccc tttgagcttt gttttcaaac caaacaggtg agttgcagct     4620

ctccccccgg cccctgcact cttcagacat ttggtccctg cccactccta aacgctcagt     4680

cccaaaacaa aatagcgaaa gacaggagga gtcaggatgt ggcagtgctg ccttcacact     4740

ttccacttcg caagttcttt taaaggttcc aaagatctcc agaccattct ctgccaaacc     4800

ctgccgcctc ctgcacgtat tgcaggtctc tggggagcaa gaaatgtcct gtttgggtga     4860

ggattccgtc acctaaaaag atctttaact tctcccccaa agtgggaagg taactttctc     4920

ccccttttcc ccaccacctt cactcctaca cccccaatta ccttgcattt tctttccttc     4980

cttctggcct ccacacccat agctttcctc catccccact taaagaaccg aagaggcttt     5040

taaagacctg gctgctttgt tttccttggc caaggaagcc actttctctc aagcaattat     5100

ttcatatcct acgaaaactt tggtcgaatg gaaaactcga aacctcgagc ttatctacac     5160

actgttcctc tgctacaatg ctttcctagt taagagtgtt tatagagaat ttgtcatcac     5220

atctgatatc ctgtacttgt aatacattat gtggaaagga aataacctta aaccgtctga     5280

tgttgcctca agagcccaaa cggcgtttcc ccacctttga cgatgtatgt gaaattactg     5340

gcttaaaaaa aaaagtatca attttttttt aacggaatga acactatcct tctttaaatg     5400

ccaaaatcga ctccaccttt gagttggtct ctaattctct aacattgttt ttgccacaca     5460

atcaagaaat atcaatctat tgactcttca cgagaagagc tctggagggt attcatgtta     5520

agtttgtata tatttattta tgcttaattt aatgggaatg tgtaaatatg gcgagcaagt     5580

agtttgggat tatttatctg tgaatctata cctctgtgaa tgggtggtta aaaaacctct     5640

tgaccctaga tagaatccta tctgaatttt tctgttcttt ataaacaagc tgttatggta     5700

atgggtagaa attggtttat tgtccagtgt taatctgatt tacataaata aaaagattgt     5760

tgtgttttca                                                            5770


<210>  809
<211>  2551
<212>  DNA
<213>  homo sapiens

<400>  809
gtagggagag aactctggag gaacgctgag ctgagcagca ccgaggacag cgcccggcag       60

cgcccgcgcc caggtctccc tccgcagccc tgactcgcgc acacgctgag cttttgctca      120

ctccccctcg cgcggacaca gacacacgca tattcacaca cccagacaca caccccgctg      180

tacaatggca gaatcccacc tgcagtcatc cctcatcaca gcctcacagt ttttcgagat      240

ctggctccat ttcgacgctg acggaagtgg ttacctggaa ggaaaggagc tgcagaactt      300

gatccaggag ctccagcagg cgcgaaagaa ggctggattg gagttatcac ctgaaatgaa      360

aacttttgtg gatcagtatg ggcaaagaga tgatggaaaa ataggaattg tagagttggc      420

tcacgtatta cccacagaag agaatttcct gctgctcttc cgatgccagc agctgaagtc      480

ctgtgaggaa ttcatgaaga catggagaaa atatgatact gaccacagtg gcttcataga      540

aactgaggag cttaagaact ttctaaagga cctgctagaa aaagcaaaca agactgttga      600

tgacacaaaa ttagccgagt atacagacct aatgctgaaa ctatttgatt caaataatga      660

tgggaagctg gaattaactg agatggccag gttactacca gtgcaggaga attttcttct      720

taaattccag ggaatcaaaa tgtgtgggaa agagttcaat aaggcttttg agctgtatga      780

tcaggacggc aatggataca tagatgaaaa tgaactggat gctttactga aggatctgtg      840

cgagaagaat aaacaggatc tggatattaa taatattaca acatacaaga agaacataat      900

ggctttgtcg gatggaggga agctgtaccg aacggatctt gctcttattc tctgtgctgg      960

ggataactag agttggtggc cgcaaccact tgctagtgat acactgtatc taaaaaataa     1020

ctgtgcacta taagggagta ggctgtattt tcttttatat ctgtaaattt aactgcatat     1080

agataattat ccaggatgtg tggctcattc ttttcagctt gtttctatac tgtttgtaat     1140

atacagtttt tgtaaccata tgattgaaaa gaagaaagtc tatgcttagg ccagtcagta     1200

cacccaattt taaaaaataa catattcttg ctttcacaaa tatagttgaa caagatttcc     1260

ctaaaaattc caccaggatt aatctctaaa attctagtct ctgatttgca aatgcacatt     1320

tgtcactgaa taatggaatt atgtataaca agccaaacat tcttatttta gacaaccata     1380

gaactgtccc acaaaatatt tctaagctta tttctaacta ttaggaggaa tgtgcttttc     1440

catctaaaat actcaccaaa atatagttaa ttgtggcttt atgaagttaa cagtctcatt     1500

acagatttag tttaccaatc aacagcatgt ctactgcttg gatccataca aaactatcgg     1560

ttcaagttga tgtgacaagg gaagggagca ccagatgaca cataaatctg tctgattcta     1620

tgcctgtatt tccaacaaac ttactgtcag agaatatgac ctaaatccat tttctaaact     1680

gttttcatgt gttgcaaatt attctagtca actgctgttt tatgtcatac tctgtgtaat     1740

ctctgattaa atttaatata ctgcatatcc tggtgtctag tttgcatact tcctggattt     1800

tctttctatg tagaactgtt catttccacc aagggtatct gctgcctctg aaaatatttt     1860

tttctagcta taacaactct attttttact acataattaa attttaatgt aaaattcata     1920

gcatcctgat tattgaatgt tatatcatca atacttttgt gtattctgtg gattctatat     1980

ttcatattga gatcagcatt caaaatagtt ctatttctat ctgcaaatag tttcaaatga     2040

gtttaaaaaa ataacatctg aaaagaaatg ctaatgtaat catttatctt atctagcaag     2100

aagattctaa aacattcttt aacatacatc taagtcagtt tcacatattt gtagctagaa     2160

tatcctatac tggttatagt tgatatgtaa cagttggtga ttttagattt ctttgattgt     2220

gaaacaggga gctatgagag atgtgtccat gtgaaattta cagttactgc ctaggagtta     2280

atgatcgttc tgggtcagct tgaatgtccc cattctataa attcaacact tattttctga     2340

attcataaaa ataaccaaaa aatgtgagct ataatgtttc cctcaagaac aaacagaaac     2400

gagatttgcc aaaaactaaa attcaacaaa tgatgttgag tgggagattg gctttgcctt     2460

tagcgtgtaa atggaagcac tgccattaga ctgaatttaa ctactaagaa taaataaaga     2520

agaaaataac cttaaaaaaa aaaaaaaaaa a                                    2551


<210>  810
<211>  3791
<212>  DNA
<213>  homo sapiens

<400>  810
aagagggggc ggggcggaag cggcggcggc gcgcgcaaag ctgcagcgtc tggaaaaaag       60

cgacttgtgg cggtcgagcg tggcgcaggc gaatcctcgg cactaagcaa atatggacct      120

cgcggcggca gcggagccgg gcgccggcag ccagcacctg gaggtccgcg acgaggtggc      180

cgagaagtgc cagaaactgt tcctggactt cttggaggag tttcagagca gcgatggaga      240

aattaaatac ttgcaattag cagaggaact gattcgtcct gagagaaaca cattggttgt      300

gagttttgtg gacctggaac aatttaacca gcaactttcc accaccattc aagaggagtt      360

ctatagagtt tacccttacc tgtgtcgggc cttgaaaaca ttcgtcaaag accgtaaaga      420

gatccctctt gccaaggatt tttatgttgc attccaagac ctgcctacca gacacaagat      480

tcgagagctc acctcatcca gaattggttt gctcactcgc atcagtgggc aggtggtgcg      540

gactcaccca gttcacccag agcttgtgag cggaactttt ctgtgcttgg actgtcagac      600

agtgatcagg gatgtagaac agcagttcaa atacacacag ccaaacatct gccgaaatcc      660

agtttgtgcc aacaggagga gattcttact ggatacaaat aaatcaagat ttgttgattt      720

tcaaaaggtt cgtattcaag agacccaagc tgagcttcct cgagggagta tcccccgcag      780

tttagaagta attttaaggg ctgaagctgt ggaatcagct caagctggtg acaagtgtga      840

ctttacaggg acactgattg ttgtgcctga cgtctccaag cttagcacac caggagcacg      900

tgcagaaact aattcccgtg tcagtggtgt tgatggatat gagacagaag gcattcgagg      960

actccgggcc cttggtgtta gggacctttc ttataggctg gtctttcttg cctgctgtgt     1020

tgcgccaacc aacccaaggt ttggggggaa agagctcaga gatgaggaac agacagctga     1080

gagcattaag aaccaaatga ctgtgaaaga atgggagaaa gtgtttgaga tgagtcaaga     1140

taaaaatcta taccacaatc tttgtaccag cctgttccct actatacatg gcaatgatga     1200

agtaaaacgg ggtgtcctgc tgatgctctt tggtggcgtt ccaaagacaa caggagaagg     1260

gacctctctt cgaggggaca taaatgtttg cattgttggt gacccaagta cagctaagag     1320

ccaatttctc aagcacgtgg aggagttcag ccccagagct gtctacacca gtggtaaagc     1380

gtccagtgct gctggcttaa cagcagctgt tgtgagagat gaagaatctc atgagtttgt     1440

cattgaggct ggagctttga tgttggctga taatggtgtg tgttgtattg atgaatttga     1500

taagatggac gtgcgggatc aagttgctat tcatgaagct atggaacagc agaccatatc     1560

catcactaaa gcaggagtga aggctactct gaacgcccgg acgtccattt tggcagcagc     1620

aaacccaatc agtggacact atgacagatc aaaatcattg aaacagaata taaatttgtc     1680

agctcccatc atgtcccgat tcgatctctt ctttatcctt gtggatgaat gtaatgaggt     1740

tacagattat gccattgcca ggcgcatagt agatttgcat tcaagaattg aggaatcaat     1800

tgatcgtgtc tattccctcg atgatatcag aagatatctt ctctttgcaa gacagtttaa     1860

acccaagatt tccaaagagt cagaggactt cattgtggag caatataaac atctccgcca     1920

gagagatggt tctggagtga ccaagtcttc atggaggatt acagtgcgac agcttgagag     1980

catgattcgt ctctctgaag ctatggctcg gatgcactgc tgtgatgagg tccaacctaa     2040

acatgtgaag gaagctttcc ggttactgaa taaatcaatc atccgtgtgg aaacacctga     2100

tgtcaatcta gatcaagagg aagagatcca gatggaggta gatgagggtg ctggtggcat     2160

caatggtcat gctgacagcc ctgctcctgt gaacgggatc aatggctaca atgaagacat     2220

aaatcaagag tctgctccca aagcctcctt aaggctgggc ttctctgagt actgccgaat     2280

ctctaacctt attgtgcttc acctcagaaa ggtggaagaa gaagaggacg agtcagcatt     2340

aaagaggagc gagcttgtta actggtactt gaaggaaatc gaatcagaga tagactctga     2400

agaagaactt ataaataaaa aaagaatcat agagaaagtt attcatcgac tcacacacta     2460

tgatcatgtt ctaattgagc tcacccaggc tggattgaaa ggctccacag agggaagtga     2520

gagctatgaa gaagatccct acttggtagt taaccctaac tacttgctcg aagattgaga     2580

tagtgaaagt aactgaccag agctgaggaa ctgtggcaca gcacctcgtg gcctggagcc     2640

tggctggagc tctgctaggg acagaagtgt ttctggaagt gatgcttcca ggatttgttt     2700

tcagaaacaa gaattgagtt gatggtccta tgtgtcacat tcatcacagg tttcatacca     2760

acacaggctt cagcacttcc tttggtgtgt ttcctgtccc agtgaagttg gaaccaaata     2820

atgtgtagtc tctataacca atacctttgt tttcatgtgt aagaaaaggc ccattacttt     2880

taaggtatgt gctgtcctat tgagcaaata actttttttc aattgccagc tactgctttt     2940

attcatcaaa ataaaataac ttgttctgaa gttgtctatt ggatttcttt ctactgtacc     3000

ctgattatta cttccatcta cttctgaatg tgagactttc cctttttgct taacctggag     3060

tgaagaggta gaactgtggt attatggatg aggtttctat gagaaggagt cattagagaa     3120

ctcatatgaa agctagaggc cttagagatg actttccaag gttaattcca gttgtttttt     3180

ttttttttta agtttataaa agtttattat acttttttaa aattactctt tagtaattta     3240

ttttacttct gtgtcctaag ggtaatttct caggattgtt ttcaaattgc ttttttaggg     3300

gaaataggtc atttgctata ttacaagcaa tccccaaatt ttatggtctt ccaggaaaag     3360

ttattaccgt ttatgatact aacagttcct gagacttagc tatgatcagt atgttcatga     3420

ggtggagcag ttcctgtgtt gcagctttta acaacagatg gcattcatta aatcacaaag     3480

tatgttaaag gtcacaaaag caaaataact gtctgaggct aaggcccacg tgggacagtc     3540

taatacccat gagtactcaa cttgccttga tgtctgagct ttccagtgca atgtgaattt     3600

gagcagccag aaatctatta gtagaaagca agacagatta atataggtta aaacaatgat     3660

ttaaatatgt ttctcccaat aattatctct ttccctggaa tcaacttgta tgaaaccttg     3720

tcaaaatgta ctccacaagt atgtacaatt aagtatttta aaaataaatg gcaaacatta     3780

aaaacaaaaa a                                                          3791


<210>  811
<211>  5544
<212>  DNA
<213>  homo sapiens

<400>  811
acttcgcctc gcagctcccc ttcccatcac cgccccctgc tcctccccgg cgtctgcgat       60

tttcccaggc acccggtgtg agtgcggcgt gcgtgtgagt gtgtgtcagg gtattgtgtt      120

gtgggagagt gtgtgagtgt gtgtgagtgt gtgtgtgcat gagtgtgtgg agtgcggggc      180

tcctgcgctc cgctcgccgc cgccgccggg gaaggacaga cggacggcgc ttcctccttc      240

ggcgagcggt tcccgggcac ctcggcttgg cccgggcgcg agtggagcgc gcctggctgg      300

ccgccggcct cctgaaggtc ccgttgcgta ccccctgggc tggatatgtt catgttcacg      360

tgaagatgga tttactgtac ggtctcgtgt ggctgctgac agtcctcctg gaggggatct      420

ctggccaagg agtgtacgct cctcccacgg ttcgtattgt gcactcaggc ttggcctgta      480

acattgaaga ggagcgctac tccgaaaggg tctacactat ccgggaagga gaaacccttg      540

agttgacttg tctagtcaca ggacatccac gtccacagat caggtggacc aaaacagcag      600

gaagtgcctc tgacagattc caagactcaa gtgtcttcaa tgagactttg aggattacaa      660

atattcagcg acaccaagga ggccggtatt actgtaaagc agagaatggc ttggggtctc      720

cagcgataaa gtcaatcaga gtggatgtat actatttgga tgatccagta gtaactgttc      780

atcaaagtat aggtgaagct aaagaacaat tttactatga gagaacagtg ttcctccggt      840

gtgttgccaa ttccaatcct cctgttcggt atagctggag acgtggccag gaggtcttgc      900

tgcaaggatc tgataaagga gttgagattt atgaaccatt ctttacccag ggtgaaacaa      960

agatcttaaa actaaagaat cttcgacctc aggactatgc taattatagc tgcattgctt     1020

cagtgaggaa tgtatgtaat attcctgata agatggtgtc gtttagactg tccaataaaa     1080

cagcatcacc gtcaattaaa ctcttggtgg atgatcctat agttgtaaat cctggagagg     1140

ccataacatt agtatgtgtt acaacaggag gagagcctgc accttctctc acctgggtca     1200

ggtcctttgg gactctgcct gaaaagactg ttttgaatgg aggaactttg accatacctg     1260

ccatcacctc agatgatgct ggtacttaca gctgcattgc caataataat gtgggaaacc     1320

ctgcaaaaaa gtccaccaac atcattgtga gagcattaaa aaaaggacga ttttggatca     1380

caccagatcc ttatcacaaa gatgacaaca tccagattgg ccgtgaggtg aaaatatctt     1440

gccaagtaga agctgttcct tctgaggagc taacatttag ttggtttaaa aatggtcgtc     1500

cattaagaag ttctgagcgg atggtcatta cacagactga tcctgatgtc tctccgggaa     1560

caacaaactt ggacatcatt gatttaaaat tcacggattt tgggacgtac acatgtgtag     1620

catctctgaa gggaggagga atatctgata tcagtatcga tgttaatata tccagcagca     1680

cagttccacc caatctgact gttccacagg aaaaatcacc attggtcacc agagaaggag     1740

acacaataga actgcaatgt caagtaactg gcaaacctaa accaatcatc ctttggtcta     1800

gagcggataa agaagttgca atgcctgatg gatcaatgca aatggagagt tatgatggaa     1860

cactgaggat tgtgaatgta tctagggaaa tgtcaggaat gtacagatgt cagaccagcc     1920

aatacaatgg atttaacgtg aaaccaaggg aagccttggt gcagctcatc gttcagtatc     1980

cccctgcagt ggaaccagca ttcttggaaa tccggcaagg acaggatcga agtgtcacta     2040

tgagttgcag agtactgaga gcctatccaa tacgggtgct gacctatgag tggcgcttgg     2100

gcaataaatt attacggacg ggtcaatttg actctcagga atacacagag tacgctgtga     2160

agagtctttc caatgaaaac tatggggttt ataactgtag catcataaat gaagctggag     2220

ctgggagatg cagctttctt gttacaggaa aggcctatgc tccagaattc tattatgata     2280

cctacaatcc agtatggcag aacagacacc gtgtttattc ttacagtcta cagtggacac     2340

agatgaatcc tgatgcagtg gatcggattg ttgcataccg gttgggcatc aggcaggctg     2400

gacagcagcg ctggtgggag caggagatta aaataaatgg gaatattcaa aagggagaat     2460

taattacata taacttgaca gagctaatta aaccagaagc ttatgaagtc cgactgactc     2520

ctctcaccaa atttggtgaa ggagattcaa caattcgtgt gatcaaatat agtgctcctg     2580

taaatcctca tttgagagaa tttcattgtg gatttgaaga tggtaatatt tgtttgttca     2640

ctcaagatga tacagataat tttgactgga caaagcaaag tacagcaaca agaaatacaa     2700

aatatactcc taatacagga cctaatgctg accgtagtgg ctccaaagaa ggtttttata     2760

tgtacattga gacatcacga cccagattgg aaggcgaaaa ggctcgactt ctcagccctg     2820

ttttcagcat agctcccaaa aacccttatg gacccacaaa cactgcatat tgtttcagct     2880

tcttttatca catgtatgga caacatatag gtgtcttaaa tgtttatcta cgtttgaaag     2940

ggcaaacaac aatagagaat ccactgtggt cttcaagtgg gaataaagga caaagatgga     3000

atgaggctca tgttaatata tacccaatta cttcatttca gctcattttt gaaggtatcc     3060

gaggtcctgg aatagaaggt gacattgcta ttgatgatgt atcaattgca gaaggagaat     3120

gtgcaaaaca agacctagca actaagaatt ccgttgatgg tgctgttggg attttggttc     3180

atatatggct ttttcccatt atcgtcctca tctctatctt aagtcctcga aggtgacctt     3240

atcctggcag aggctataaa agattcacca ggcactggca tgaagaaaga gtctttgtaa     3300

atggacattg aacaaacaaa ctaccaaaga ttcctccact gactactgac tcaaaaataa     3360

aataataaaa acaaattttt ttaagcactg gggataaaaa gacatcatgg aagtataact     3420

tattccagac taaacataaa agataatctt gacctgagta gagaagagac cttcaggtgc     3480

ttttgtggct aaaaagatta cagcgtcatc tggttgaact ctggaaaaaa aaaaaaaaat     3540

gaaaaaaaga aaaaaaaaag agctatagaa atccttgtca aagcacaaag tcatggctgg     3600

ttttgtttca aatgaatagt ttgcttgtta ccatggaaac ctaatggcct gccaacaaaa     3660

acctcactgt aaacagggta cgtgaagagc tggcatttat tttccttacg agaaggtttt     3720

cgtagagaat taaataaatg taggcccttt tacctttggc tgttaccctt ccttgaaaat     3780

aacccgaact cagaattatt taaagcattc atgtttctcc ccaccttatc cccatcccac     3840

ctttattatt attatttttc tcccatggct aagctagata actgtatgct gtctcttttt     3900

gcatgcacta ctatccagga tggtaaacct gggcttacat gttacacagg cttatcggag     3960

tttgcttgcg gccacttgaa cacccaaact acgtcatctg ttccaatgaa gaaaccaaac     4020

caccatcttt tataaattgc catggaaacc aagtgccttc aatgaaacaa gcctgaataa     4080

ttttcaactc agaagcttgc actgctaaga gtggtttgtg taaaactatt ttataaacaa     4140

actacagagc ctaaatgtgc aaattacagg caagacaaca aagccgcttc tgaagaagaa     4200

aggaccgaag ctgctgcgta agcccatgca gacaagatat ttgttgttta acctcctaga     4260

cagccatggc ctttcggctt attgtccatt agaaaatcac ttccattgag accagacatg     4320

gagcaacact ttttttcttc caggttatta aatgggtcaa ccagagcaaa aggttattaa     4380

gaatacttag tgcagaaggt ggtaaaacac aaaagtgatt tttttactct aacctccatt     4440

tgaaatgaaa ttggccctag ctttagaggg aacaagaaaa tgtttgggat tgcagtgcat     4500

actaactcta cagtggaact gggcctgaaa aatctggctt tattctaaac tctgagggta     4560

atatgcctct gccctttagt cagactctgt gcaaattgtg aaatattatt ttattatttt     4620

accaagatta taaaaacact tttacaaaaa aacaaaaacc tgtaaaaata attttgagct     4680

acctgacgac aaatcatatc tttaaccagc cagttttcca atgcattgta aatttcactt     4740

aaacctgttg gttatgaaaa tttgaagatc attttcctta aattatctca gcttttaact     4800

tcatttaaaa agacttttgt ctaagaagaa tattattatt atatgttctt tcaacacccc     4860

aggattaaaa aaactgatta tgcaagcaat tggaatataa gtattaaatt atagcatttg     4920

caaatattaa tataaaagca caacaaaatg tagtggaaaa tgacaaagct tgttttttaa     4980

aacaattctg tagaaatgtt tgtgcaaatt cagtaattca acttaaaata taattttaca     5040

gctatgttca ataaagcctc tttccaggta aggtatgaca agcagtatgt gtgtttgttg     5100

agcaatgttc acttatcact aaaatgaaat tagttataca atttattggt taccatggga     5160

taaatcttca gtgctccaca taccttaatg tctgcagaaa gaaattttaa taggaactcc     5220

ctgatgcact cccctatatt gtaatacatg cagaaagcag ttaaaccttt gaaggtaaaa     5280

tatgaaacat atatgaacct ggaatttaat gtctattttc agtcagttca aaaggggacc     5340

agtttgaata tttaggtagt gatggaattg atctgaacca agtcctttaa attaaacata     5400

ataaacaaat gagtttcata acttatttga atgaattaga catcttaaaa ttttttcaga     5460

gtttcacagt aacccatata ctttatcaga ccaaagagat tcaagtacac aatatctggg     5520

gcatttcttt tacgttttac aaaa                                            5544


<210>  812
<211>  5250
<212>  DNA
<213>  homo sapiens

<400>  812
taatcgttcc tgaaaaaaac aaacaaacaa aaaaaatcac cattcctttt aatagcttga       60

gcctgtacca gaatgataag tggaaattag tcctcaaagt aacctcagct gtttcattat      120

tgtgtgcctc gagcatctgg ttattcaagc tcctcccacg gttcgtattg tgcactcagg      180

cttggcctgt aacattgaag aggagcgcta ctccgaaagg gtctacacta tccgggaagg      240

agaaaccctt gagttgactt gtctagtcac aggacatcca cgtccacagg tggaccaaaa      300

cagcaggaag tgcctctgac agattccaag actcaagtgt cttcaatgag actttgagga      360

ttacaaatat tcagcgacac caaggaggcc ggtattactg taaagcagag aatggcttgg      420

ggtctccagc gataaagtca atcagagtgg atgtatacta tttggatgat ccagtagtaa      480

ctgttcatca aagtataggt gaagctaaag aacaatttta ctatgagaga acagtgttcc      540

tccggtgtgt tgccaattcc aatcctcctg ttcggtatag ctggagacgt ggccaggagg      600

tcttgctgca aggatctgat aaaggagttg agatttatga accattcttt acccagggtg      660

aaacaaagat cttaaaacta aagaatcttc gacctcagga ctatgctaat tatagctgca      720

ttgcttcagt gaggaatgta tgtaatattc ctgataagat ggtgtcgttt agactgtcca      780

ataaaacagc atcaccgtca attaaactct tggtggatga tcctatagtt gtaaatcctg      840

gagaggccat aacattagta tgtgttacaa caggaggaga gcctgcacct tctctcacct      900

gggtcaggtc ctttgggact ctgcctgaaa agactgtttt gaatggagga actttgacca      960

tacctgccat cacctcagat gatgctggta cttacagctg cattgccaat aataatgtgg     1020

gaaaccctgc aaaaaagtcc accaacatca ttgtgagagc attaaaaaaa ggacgatttt     1080

ggatcacacc agatccttat cacaaagatg acaacatcca gattggccgt gaggtgaaaa     1140

tatcttgcca agtagaagct gttccttctg aggagctaac atttagttgg tttaaaaatg     1200

gtcgtccatt aagaagttct gagcggatgg tcattacaca gactgatcct gatgtctctc     1260

cgggaacaac aaacttggac atcattgatt taaaattcac ggattttggg acgtacacat     1320

gtgtagcatc tctgaaggga ggaggaatat ctgatatcag tatcgatgtt aatatatcca     1380

gcagcacagt tccacccaat ctgactgttc cacaggaaaa atcaccattg gtcaccagag     1440

aaggagacac aatagaactg caatgtcaag taactggcaa acctaaacca atcatccttt     1500

ggtctagagc ggataaagaa gttgcaatgc ctgatggatc aatgcaaatg gagagttatg     1560

atggaacact gaggattgtg aatgtatcta gggaaatgtc aggaatgtac agatgtcaga     1620

ccagccaata caatggattt aacgtgaaac caagggaagc cttggtgcag ctcatcgttc     1680

agtatccccc tgcagtggaa ccagcattct tggaaatccg gcaaggacag gatcgaagtg     1740

tcactatgag ttgcagagta ctgagagcct atccaatacg ggtgctgacc tatgagtggc     1800

gcttgggcaa taaattatta cggacgggtc aatttgactc tcaggaatac acagagtacg     1860

ctgtgaagag tctttccaat gaaaactatg gggtttataa ctgtagcatc ataaatgaag     1920

ctggagctgg gagatgcagc tttcttgtta caggaaaggc ctatgctcca gaattctatt     1980

atgataccta caatccagta tggcagaaca gacaccgtgt ttattcttac agtctacagt     2040

ggacacagat gaatcctgat gcagtggatc ggattgttgc ataccggttg ggcatcaggc     2100

aggctggaca gcagcgctgg tgggagcagg agattaaaat aaatgggaat attcaaaagg     2160

gagaattaat tacatataac ttgacagagc taattaaacc agaagcttat gaagtccgac     2220

tgactcctct caccaaattt ggtgaaggag attcaacaat tcgtgtgatc aaatatagtg     2280

ctcctgtaaa tcctcatttg agagaatttc attgtggatt tgaagatggt aatatttgtt     2340

tgttcactca agatgataca gataattttg actggacaaa gcaaagtaca gcaacaagaa     2400

atacaaaata tactcctaat acaggaccta atgctgaccg tagtggctcc aaagaaggtt     2460

tttatatgta cattgagaca tcacgaccca gattggaagg cgaaaaggct cgacttctca     2520

gccctgtttt cagcatagct cccaaaaacc cttatggacc cacaaacact gcatattgtt     2580

tcagcttctt ttatcacatg tatggacaac atataggtgt cttaaatgtt tatctacgtt     2640

tgaaagggca aacaacaata gagaatccac tgtggtcttc aagtgggaat aaaggacaaa     2700

gatggaatga ggctcatgtt aatatatacc caattacttc atttcagctc atttttgaag     2760

gtatccgagg tcctggaata gaaggtgaca ttgctattga tgatgtatca attgcagaag     2820

gagaatgtgc aaaacaagac ctagcaacta agaattccgt tgatggtgct gttgggattt     2880

tggttcatat atggcttttt cccattatcg tcctcatctc tatcttaagt cctcgaaggt     2940

gaccttatcc tggcagaggc tataaaagat tcaccaggca ctggcatgaa gaaagagtct     3000

ttgtaaatgg acattgaaca aacaaactac caaagattcc tccactgact actgactcaa     3060

aaataaaata ataaaaacaa atttttttaa gcactgggga taaaaagaca tcatggaagt     3120

ataacttatt ccagactaaa cataaaagat aatcttgacc tgagtagaga agagaccttc     3180

aggtgctttt gtggctaaaa agattacagc gtcatctggt tgaactctgg aaaaaaaaaa     3240

aaaaatgaaa aaaagaaaaa aaaaagagct atagaaatcc ttgtcaaagc acaaagtcat     3300

ggctggtttt gtttcaaatg aatagtttgc ttgttaccat ggaaacctaa tggcctgcca     3360

acaaaaacct cactgtaaac agggtacgtg aagagctggc atttattttc cttacgagaa     3420

ggttttcgta gagaattaaa taaatgtagg cccttttacc tttggctgtt acccttcctt     3480

gaaaataacc cgaactcaga attatttaaa gcattcatgt ttctccccac cttatcccca     3540

tcccaccttt attattatta tttttctccc atggctaagc tagataactg tatgctgtct     3600

ctttttgcat gcactactat ccaggatggt aaacctgggc ttacatgtta cacaggctta     3660

tcggagtttg cttgcggcca cttgaacacc caaactacgt catctgttcc aatgaagaaa     3720

ccaaaccacc atcttttata aattgccatg gaaaccaagt gccttcaatg aaacaagcct     3780

gaataatttt caactcagaa gcttgcactg ctaagagtgg tttgtgtaaa actattttat     3840

aaacaaacta cagagcctaa atgtgcaaat tacaggcaag acaacaaagc cgcttctgaa     3900

gaagaaagga ccgaagctgc tgcgtaagcc catgcagaca agatatttgt tgtttaacct     3960

cctagacagc catggccttt cggcttattg tccattagaa aatcacttcc attgagacca     4020

gacatggagc aacacttttt ttcttccagg ttattaaatg ggtcaaccag agcaaaaggt     4080

tattaagaat acttagtgca gaaggtggta aaacacaaaa gtgatttttt tactctaacc     4140

tccatttgaa atgaaattgg ccctagcttt agagggaaca agaaaatgtt tgggattgca     4200

gtgcatacta actctacagt ggaactgggc ctgaaaaatc tggctttatt ctaaactctg     4260

agggtaatat gcctctgccc tttagtcaga ctctgtgcaa attgtgaaat attattttat     4320

tattttacca agattataaa aacactttta caaaaaaaca aaaacctgta aaaataattt     4380

tgagctacct gacgacaaat catatcttta accagccagt tttccaatgc attgtaaatt     4440

tcacttaaac ctgttggtta tgaaaatttg aagatcattt tccttaaatt atctcagctt     4500

ttaacttcat ttaaaaagac ttttgtctaa gaagaatatt attattatat gttctttcaa     4560

caccccagga ttaaaaaaac tgattatgca agcaattgga atataagtat taaattatag     4620

catttgcaaa tattaatata aaagcacaac aaaatgtagt ggaaaatgac aaagcttgtt     4680

ttttaaaaca attctgtaga aatgtttgtg caaattcagt aattcaactt aaaatataat     4740

tttacagcta tgttcaataa agcctctttc caggtaaggt atgacaagca gtatgtgtgt     4800

ttgttgagca atgttcactt atcactaaaa tgaaattagt tatacaattt attggttacc     4860

atgggataaa tcttcagtgc tccacatacc ttaatgtctg cagaaagaaa ttttaatagg     4920

aactccctga tgcactcccc tatattgtaa tacatgcaga aagcagttaa acctttgaag     4980

gtaaaatatg aaacatatat gaacctggaa tttaatgtct attttcagtc agttcaaaag     5040

gggaccagtt tgaatattta ggtagtgatg gaattgatct gaaccaagtc ctttaaatta     5100

aacataataa acaaatgagt ttcataactt atttgaatga attagacatc ttaaaatttt     5160

ttcagagttt cacagtaacc catatacttt atcagaccaa agagattcaa gtacacaata     5220

tctggggcat ttcttttacg ttttacaaaa                                      5250


<210>  813
<211>  882
<212>  DNA
<213>  homo sapiens

<400>  813
ctgagagatc ctctaccgca gtcgtttgag gaggcggaac tgaagttttt tcttaattat       60

catgtgacgg gttctggatt taatgggggg aaaagggcgg aaaaggacaa ggatccaaac      120

tggcgaattt gctgatcttc gcgtccctct ccgctttccg gccggcagcg ctgccagggt      180

atatttcctt ttttccgatc ctgcaacagc ctctttaaac tgtttaaatg agaatgtcct      240

tggctcagag agtactactc acctggcttt tcacactact cttcttgatc atgttggtgt      300

tgaaactgga tgagaaagca ccttggaact ggttcctcat attcattcca gtctggatat      360

ttgatactat ccttcttgtc ctgctgattg tgaaaatggc tgggcggtgt aagtctggct      420

ttgaccctcg acatggatca cacaatatta aaaaaaaagc ctggtacctc attgcaatgt      480

tacttaaatt agccttctgc ctcgcactct gtgctaaact ggaacagttt actaccatga      540

atctatccta tgtcttcatt cctttatggg ccttgctggc tggggcttta acagaactcg      600

gatataatgt cttttttgtg agagactgac ttctaagtac atcatctcct ttctattgct      660

gttcaacaag ttaccattaa agtgttctga atctgtcaag cttcaagaat accagagaac      720

tgagggaaaa taccaaatgt agttttatac tacttccata aaacaggatt ggtgaatcac      780

ggacttctag tcaacctaca gcttaattat tcagcatttg agttattgag atccttatta      840

tctctatgta aataaagttt gttttggacc tcaaaaaaaa aa                         882


<210>  814
<211>  882
<212>  DNA
<213>  homo sapiens

<400>  814
ctgagagatc ctctaccgca gtcgtttgag gaggcggaac tgaagttttt tcttaattat       60

catgtgacgg gttctggatt taatgggggg aaaagggcgg aaaaggacaa ggatccaaac      120

tggcgaattt gctgatcttc gcgtccctct ccgctttccg gccggcagcg ctgccagggt      180

atatttcctt ttttccgatc ctgcaacagc ctctttaaac tgtttaaatg agaatgtcct      240

tggctcagag agtactactc acctggcttt tcacactact cttcttgatc atgttggtgt      300

tgaaactgga tgagaaagca ccttggaact ggttcctcat attcattcca gtctggatat      360

ttgatactat ccttcttgtc ctgctgattg tgaaaatggc tgggcggtgt aagtctggct      420

ttgaccctcg acatggatca cacaatatta aaaaaaaagc ctggtacctc attgcaatgt      480

tacttaaatt agccttctgc ctcgcactct gtgctaaact ggaacagttt actaccatga      540

atctatccta tgtcttcatt cctttatggg ccttgctggc tggggcttta acagaactcg      600

gatataatgt cttttttgtg agagactgac ttctaagtac atcatctcct ttctattgct      660

gttcaacaag ttaccattaa agtgttctga atctgtcaag cttcaagaat accagagaac      720

tgagggaaaa taccaaatgt agttttatac tacttccata aaacaggatt ggtgaatcac      780

ggacttctag tcaacctaca gcttaattat tcagcatttg agttattgag atccttatta      840

tctctatgta aataaagttt gttttggacc tcaaaaaaaa aa                         882


<210>  815
<211>  9186
<212>  DNA
<213>  homo sapiens

<400>  815
gcgcgccccg gcgccgcgcc cggccgggag ccgcctgttg atcgccgcgc tcgccccggc       60

cacggcgccg cccctgttct cccggccccg ctccaccggg gctgacggac tgacggccag      120

cacagccggc tccgggatga gcgcacggac ggtattctga agtctcagga aactggacca      180

tttaaatgtg catggcccat gagaaaggct tataagaagc catggcactc ccctttcaaa      240

aagagctgga gaaatacaag aacattgatg aagatgagct tcttggcaaa ctctcagaag      300

aggaactgaa acagttggaa aatgttctag atgacctaga tcctgagagt gccatgctgc      360

cagctggatt tcgacagaaa gaccagacac agaaggcagc caccggcccc tttgaccgcg      420

agcacctcct catgtacctg gagaaggagg ctttggaaca gaaagacaga gaggactttg      480

tgcccttcac tggagaaaag aaagggagag tctttatccc taaagaaaag cctatagaaa      540

ctcgtaaaga agaaaaagtg acccttgacc cagaactgga agaagctttg gccagtgcct      600

ctgacaccga actctatgat cttgcagctg tccttggagt acacaatttg ctcaacaatc      660

caaagttcga tgaagaaaca gccaacaata aaggtggcaa aggacctgtc agaaatgttg      720

tcaaaggtga aaaagtaaag ccagtatttg aggaaccacc aaatcccaca aatgtggaaa      780

taagcctgca gcagatgaaa gccaatgatc ctagcttgca agaagtcaac ctcaacaaca      840

ttaagaacat tccaattcca accctgaggg aatttgcaaa ggctctggag accaacactc      900

acgtgaagaa gttcagcctg gccgcaactc gcagcaatga ccctgtggcc attgcttttg      960

cagacatgct gaaagtaaac aagaccttga caagtctaaa catagaatcc aattttatca     1020

ctggaactgg gatcctggcc ctggtagagg cactgaaaga aaatgacacc ttgacagaaa     1080

tcaagattga caaccagagg cagcagttgg gaacagctgt agagatggaa attgcccaga     1140

tgctggagga gaattcaagg atcctcaagt ttggatacca gtttaccaag caagggccac     1200

gaacaagggt ggcagctgcc atcacaaaga ataatgacct ggttcgtaag aagagagttg     1260

aagcagaccg aaggtaaact tccttgagga gaagtgaagt ttcactgtgg tatggccatt     1320

gaaaaacaaa aactcttctt cttccccatc aggaccattt tatcaaagtt cgttcatttc     1380

cgttaaccac ataactaata atttaattgt tattcttttt tagcactact tatttatctt     1440

ggattttgta atatatgcaa ttgttttatt tgctcatggg cacttctggc aacttgacaa     1500

atggaccgat gcagatttta gagagtgacg acatggaaaa tgaatttaac cactttctta     1560

ttgggttgtc ttgctttctt acatgaactt gtttttttaa tcactgaaag gaatttagtg     1620

tataatatgt gtttgtaact gtgattatga tagaggccta tctctgttta catgcatagc     1680

tttgagttag gctaaataca tcagaagtgt tctactgacc acataagaag ttagtattgc     1740

caatctttca ctgcatgtga aaatgtgacc aatttagcac aaattctctc ttagttccag     1800

aaaaatcagt aaatgcacat gccctgttga ttggagatca gtagtgtcat cttcataaag     1860

caagacaaca ttatgacact ttaaaacagt agcaaagaag tctatttatt aacccacaaa     1920

tgtagcatca agccagactc acaggtagca aaatgaatta cacacctact tttactgact     1980

attcaacata aattgaatct ttaacatgac tttaaaggct atttacaaag ctgttttaaa     2040

gtttttcaaa catgatagaa attttctaaa ttttagtaag agagaagctt ttaaaacagt     2100

acattcctga ataaaacaac aatattgtat cttaatcaag gctgtctgat gcagatgatt     2160

gcattttttg gcaaatttta gaagcattta ttgctttgtc tttagtgtaa caagatcact     2220

ggattaaata taaacattca ggttaattat ctagattttt gtccacagta tatgatccat     2280

ccagacattt gcaaacgtca ggagaaaaat gtgaattatt tatccagatg catgtcatct     2340

caaggacaaa gcctgtgaaa gtacaagtga gatggttgca ttgtagtatg cattaatctt     2400

tcaatgtagt ggtgtaaaaa tgcagtgcta aactaatgaa gcaggtgact gcagcctttg     2460

gctcaagctc acaactctga taactgtcag tgcctgaggt tgtgattggt gacattctga     2520

cactgcccaa ggcaactcac cctctattcc tcctttctcc cctccctttc ttccaattca     2580

ttgtcttttt tttcctcttt tctctgtaat ttgttactaa acaaattcca gaatttgttt     2640

agtagctgag tgttcctgag ttgcctagta gcaataaaac aagtgaatag gaaaataatt     2700

aatatattat tctatttagc ttgtaaaaca catggaatct gtttaagata gcccttgtaa     2760

aattgaacat ttacctgtat tgtaagtacc cacatctgtg tctctgaagt cctttgaaac     2820

atctcattat cttgaaattt ttttaatgtt tgagaacacc ataagcagaa tattctaaca     2880

cctttggccc ctgaaaatcc tttaattagt ttatggcttc atctccttat ctatttaaaa     2940

aacatagtaa ataatgttta tggttttcag tctgattttt ccttcccttt cacccattta     3000

ggtgtgatgt gttggagtca acttgtacag gcttgccaac tgttatattt tcaagaattt     3060

tgcaaactgg ttgttcaata cagccattat ttaaaattaa atgatgtgca cttacaactg     3120

aatgaattat attaaggaca gaagtaacaa atactgtact caaaaatctt acattttact     3180

attttctaac ctcttagatt atttacatct agtaggtatg tatgtagaaa tattaccaaa     3240

cagtatgcta ctgaacgtat cctctcaact ccatgttcac taccttcttg ttactacagt     3300

ggcttgaaat tggccatggt agaaatattt acaccacaga aattagcaat atgtaagaaa     3360

ttggggtttt ctccctctcc agattgctgg ttgataaaca ttcatcagca caccactggg     3420

tgaaattata cattttttta tacatatgtt tcgcttatca tgttgccgaa gggaagaaca     3480

tttctcttag atgtcttttc tcctctttgg atttgttaca aacctgttta agtgctgagt     3540

ccctgacctg cctctccaag taagcctttt tccttttttt tttttttttt cttactctca     3600

ttcttgcctt gactcttaaa atcctggacc ctatagagca ttccttgcag ccccacagtg     3660

ctgtgggctg ggggctaaag cagttcttgg caaactctgg cagaaagcaa gaaaaaaaga     3720

atcagaattc aatcatggct gtttcttttg tacaagcagt tgttgatagt attaaagcaa     3780

gataatggga cattatcaaa aatatagcac tgtttttacc ttatgaaata gttgggttgc     3840

atgcaacaga gtctatgaaa tcaaatgttt tttactaatc agtttgtttt cttattacct     3900

gtgtttttaa agtggcttga aaggtggcat ttccatgagt gtgcacatat tgatgataac     3960

ccttagaaaa acatacactt gaggagccta tccatcattt aattagccta ggacttcatc     4020

tccctctctg cccaaagtgt ggaagtggta gctctttcat gatcatgggc acagttaatc     4080

ctttgctatc cattgtgatg gggcataatg tatataaaat atttttctat gtatttgttc     4140

tgccagatac tgtgttgaga tatttggcaa tatctggata actgactgaa gggagataac     4200

ttctccccag gcctatctcc ctcccccttt tagagttgtg caggtccact ttaagtgtaa     4260

aatcactcac ctggacttgt gggcttgtat caccaacatc tattatggca catgtagatg     4320

acatttagga gaaaaacctt agaagtctag aaatcatatg attagttcag cactgcagct     4380

ccccatctgc ttatagtgta taactggaag ctctttcatc ctcatcagca tgattaaatg     4440

acttcgtttc tttcatcttt ggagggtata atgtaaataa gtgtcgtgtg tgtatgtgtg     4500

tgtgtactgt cagatatcta actaggtatt tggctacatc tggacaactg attgaaggga     4560

gatgctctct ccccagtcct cttcccttgt cctttttaga attgctgcag gcccaggtta     4620

aatatgaaat tactccctag gctttgcagt ttatgttacc aaccaccaca ttttatagct     4680

atgtagagga tgactcttag gaaataaata ttagaagcct agaaatcatt tagttgttct     4740

agcaccaaat ctatccattt gcctaatgta tttaacattc catcctcatc aacatgatga     4800

agcccctttc ttccatcttt gtagggcaca ttgtatataa atattttgta cataaagatc     4860

atcaaatacc ataatggggt atttggcttc atctggaaaa ttgactggag ggagatgctg     4920

tctcccagcc ctgcttccct cgtccctgtc caagttgctg caggcccagg ttagaagatt     4980

accaacctgg aggggcatgc agttcatctt acaataaaag cccattcatt taaaaactca     5040

gaaatcatcc cagtgcctgt actcctcaaa ccaatttccc taagggaaga ctggcacacc     5100

agcccaaaga gcaggtgctt ctcttccaac agaaacatgg cccctgacag ggcaccagca     5160

ttagggaaac caatgtcctc cgaatagctg ccatgagaac atttcagatg ctcaaactga     5220

aaattcttaa aaccaatatt aagcatcagc atgctttaag tgtaagatag ccctttggaa     5280

tttacaaaca catgtgcagc tatttccttc ttcacagata tgatgtactc agccccctcc     5340

taggcactac gaagaagaca gaggaagcat aaaaattctg gactaatata attttatatg     5400

tgtttctgag attggggagt agactgagtg ccttttttac aaagaagatc ccatatttaa     5460

ttcaagtatt tatagcatca gcaaaaatgg gcagagggcg ggaagttgag aacactaggt     5520

tctgtgctat gttacctgta ttcagtagaa gtgtttctgg agtcaggttt taagtcatga     5580

tcctgaagct tccttcccct cttccactaa tgatgcaata atagctgttt tcattttaac     5640

gagcagagaa ctaagaggaa aggtcctagc tctgccttcc acttgcagct tccctttacc     5700

tcctcttatt gctttcatct caaatatccc tgctactcaa ccaatcctaa agctaaagta     5760

ctgagatgca cacaaaggaa aggtgtgaga gtgcttggaa gcatccagct gagcccactg     5820

gatgaaaatc agacgatagg gcctcctgtt gtaatatact agccagagaa aagcgccaag     5880

aacttcaggg atattattca ctgctttatt gctccctaac cctagatcag attggatttt     5940

actttgtagt tcaggagtta agaagtcaaa ttgctgaccg aggtggggaa ggatgatgga     6000

aattaaaggt ttacatttgt ttaatggcag aactgagatt tgctcagctt atctctttcc     6060

catctgtctg taatagcaat gactgaataa tcagtagacc aatggaagag gagttgcaag     6120

tttaaatttg taacctgact ctgggttctg ttctaggaat agtgcatgtt ttagaggctt     6180

tgccagttgg gatacattgt tgacttgggg gaggatgaag gagagaactg atgacctaga     6240

catagaaaag agtagttaac taactagatg ttcttctgat ctcttccatg gtagacattc     6300

tgagcacatt ggcccagtta gttggtatgg tgaaggggca ccgtactaac agatttggag     6360

actgaaacct aatcccatca ccaacactta gcaggtatat gatcatgggc aattcattca     6420

attgcctgcc aattatagac tatatagggg gaagagcact ggatttggag tcaagaaacc     6480

tggacacttg gctccacact tccttagctg ggtaactttg ggcaaaccgc ttggtctctc     6540

aagcctaagg ttcttcagct ataaaatggg aataatactt cactaactac ctcacagagt     6600

tgtggtaaga atataatcag ataactggat aaaaacacta tataaactgg aaagcgccgt     6660

acaaatgtga gagatcagtt ttattatcaa atcactgttt tccactgcct cttgaatcgg     6720

ctttattcta accaaccatt acatctttct catcttttgg agtatgggta attgaggctt     6780

gggtgtgtca tcagggactg gagttatttc agctcccatg tagaggtggg agaggtggtt     6840

gatggggcag tggaagttag ataccagcga tgtatatggt aggacatttt cctgggtcac     6900

tttgacagta ccttgggaaa ttgtcagtcc ttgcagaggg cctaggctgg gcacaaggga     6960

gaaagcgaac agttgactaa gaattgaggg gagggtctgg agcgctactg ccctcctgtc     7020

attgctgtgg gtgggagagg ctaagacttc aggtttgact ggaggcctag gagagaagag     7080

tgtccttagg gtttcaagaa ttttaatgcc tagcagctga gtaacaggca ttagttctga     7140

tagatagtga aggggagaaa gtgccacctg ttgtgagatc acctctccag ggcagcagct     7200

gccttgttat caccagcaac cttagccctg gtcagtaata tttctgctaa gaaaggtttt     7260

gaagcatggc ctccaatgac tttcataagc ccttggaggc aggactgtgt ctcatccatc     7320

tttgtatctt cagtaccatc ttgtaaggtg ccttgtacat agtaggtgct taatgaacaa     7380

atgttgcttg aatttagctg tcgtccagcc ccacagagtt atgctccatt tgccaccatg     7440

tgatattttt gagaaacaat agtgatttgg atgccagctc tatgtgactt tgggcaagac     7500

tctccatcta tcttgtcttc atttcatctg taaaatgaag tgagtagatt caatgctccc     7560

taaggtccct tccagctcca atacttgaca agcttgtgat tctaaatcgt ttccgttgcc     7620

tctgaacatg ggtgagtaat gcctccactg cagctgtttc tctccaggag gctttgttca     7680

gaggaggtct gactattgca cagccagttt tttcttcctc ttcagcagtt ctttactgtc     7740

ttcagaatgg ttctggataa gcggcctttt ctgaaaggat atttaaaaat atatactatt     7800

taggctgggc ccagtggctc atgcctgtaa tcccagcact ttgggaggtg aaggtgggtg     7860

gatcacctga ggtcaggagt tcaagaccag cctggccaac atggtgaaac cccgtctcta     7920

ctaaaaatac agaaattagc tgggccctgt ggcaagagcc tgttatccca gctactgggg     7980

aggctgaggc aggaaaatcg cttgaaccca ggaggtggag gttgtagtga gccgagatca     8040

caccactgca ctccagcctg ggtgacaaga acgaaactcc atctcaaaaa ataaaataaa     8100

atatatacta tcttgctcct cagaaccagt ggggaagaag agggaaggca aagaaagaaa     8160

ctgagcatag taaacacagc atttttttgt aggctcttat ttaaaatgtg tgtgtgtgtg     8220

tgtatgtgtg tgtttctgag taagtattga ctgggaaaaa gagagaagtc aatcaaaagt     8280

atactgtgca attgagagag gctggcccaa gatttaaaac ttcctgtggg taatctaact     8340

gtgagtagat aggaatcggc catatgacga aatgagatca ataggaaatg tgctttttga     8400

ggaaatttta ttttagtacc aaatgttgcc agtgacaatc ttcagttaag aagtaagtta     8460

ttctgaccta aaattcttat ctctgccact ttggtttaaa aacaaaaacc cttatataca     8520

tggaatagtt atattttaat taagcattta ttttagttgt tttcatccat tcaagcaaaa     8580

tgaataagca gcatttttca ttgcacttaa aaatgtaaaa tacctgcatg ccactaatct     8640

gtaacatttt accagttcag atgcctgtaa tgtgtgactt tatgtgtgtc tgtgttgttt     8700

tgaagagaat aaaggaaata atactttgca aactgtttaa acaagtgttt aaacttctat     8760

tggcaacatt tattgggcta agcagttatt gaaaactccg catagtttta ttttccattt     8820

gaaacttcaa tcaaatcaag actattatat tcattaggga attaaagact aatttgcttt     8880

ttaaatgtga agttgaacac tgtgtggaaa gtaaatgtgt gatgaagcaa aatgtataaa     8940

gtatgaaata ttatactttt accctggata attattcagg accccagttg gcccaaatag     9000

gtgcaatttt taatcctttg aaattagcca gccagaccta atgctaaggt aaatgtaaac     9060

tgttttaatt aattaagatc tttctgcttt cgaaggtata atgtatctat ttctgtcagg     9120

aatgatattt ccaaatgaaa atgtaaagaa cattgggaaa taataaactt tcctttcaaa     9180

gtaaaa                                                                9186


<210>  816
<211>  2051
<212>  DNA
<213>  homo sapiens

<400>  816
agggtgcgaa gcgccactgt ttaggtttcg ctttcccggg agcctgaccc gcccctgacg       60

tcgcctttcc cgtctccgca gggtccggcc tgcgccttcc cgccaggcct ggacactggt      120

tcaacacctg tgacttcatg tgtgcgcgcc ggccacacct gcagtcacac ctgtagcccc      180

ctctgccaag agatccatac cgaggcagcg tcggtggcta caagccctca gtccacacct      240

gtggacacct gtgacacctg gccacacgac ctgtggccgc ggcctggcgt ctgctgcgac      300

aggagccctt acctcccctg ttataacacc tgaccgccac ctaactgccc ctgcagaagg      360

agcaatggcc ttggctcctg agaggtaaga gcccggccca ccctctccag atgccagtcc      420

ccgagcgccc tgcagccggc cctgactctc cgcggccggg cacccgcagg gcagccccac      480

gcgtgctgtt cggagagtgg ctccttggag agatcagcag cggctgctat gaggggctgc      540

agtggctgga cgaggcccgc acctgtttcc gcgtgccctg gaagcacttc gcgcgcaagg      600

acctgagcga ggccgacgcg cgcatcttca aggcctgggc tgtggcccgc ggcaggtggc      660

cgcctagcag caggggaggt ggcccgcccc ccgaggctga gactgcggag cgcgccggct      720

ggaaaaccaa cttccgctgc gcactgcgca gcacgcgtcg cttcgtgatg ctgcgggata      780

actcggggga cccggccgac ccgcacaagg tgtacgcgct cagccgggag ctgtgctggc      840

gagaaggccc aggcacggac cagactgagg cagaggcccc cgcagctgtc ccaccaccac      900

agggtgggcc cccagggcca ttcctggcac acacacatgc tggactccaa gccccaggcc      960

ccctccctgc cccagctggt gacaaggggg acctcctgct ccaggcagtg caacagagct     1020

gcctggcaga ccatctgctg acagcgtcat ggggggcaga tccagtccca accaaggctc     1080

ctggagaggg acaagaaggg cttcccctga ctggggcctg tgctggaggc ccagggctcc     1140

ctgctgggga gctgtacggg tgggcagtag agacgacccc cagccccggg ccccagcccg     1200

cggcactaac gacaggcgag gccgcggccc cagagtcccc gcaccaggca gagccgtacc     1260

tgtcaccctc cccaagcgcc tgcaccgcgg tgcaagagcc cagcccaggg gcgctggacg     1320

tgaccatcat gtacaagggc cgcacggtgc tgcagaaggt ggtgggacac ccgagctgca     1380

cgttcctata cggcccccca gacccagctg tccgggccac agacccccag caggtagcat     1440

tccccagccc tgccgagctc ccggaccaga agcagctgcg ctacacggag gaactgctgc     1500

ggcacgtggc ccctgggttg cacctggagc ttcgggggcc acagctgtgg gcccggcgca     1560

tgggcaagtg caaggtgtac tgggaggtgg gcggaccccc aggctccgcc agcccctcca     1620

ccccagcctg cctgctgcct cggaactgtg acacccccat cttcgacttc agagtcttct     1680

tccaagagct ggtggaattc cgggcacggc agcgccgtgg ctccccacgc tataccatct     1740

acctgggctt cgggcaggac ctgtcagctg ggaggcccaa ggagaagagc ctggtcctgg     1800

tgaagctgga accctggctg tgccgagtgc acctagaggg cacgcagcgt gagggtgtgt     1860

cttccctgga tagcagcagc ctcagcctct gcctgtccag cgccaacagc ctctatgacg     1920

acatcgagtg cttccttatg gagctggagc agcccgccta gaacccagtc taatgagaac     1980

tccagaaagc tggagcagcc cacctagagc tggccgcggc cgcccagtct aataaaaaga     2040

actccagaac a                                                          2051


<210>  817
<211>  1972
<212>  DNA
<213>  homo sapiens

<400>  817
gaaactcccg cctggccacc ataaaagcgc cggccctccg cttccccgcg agacgaaact       60

tcccgtcccg gcggctctgg cacccagggt ccggcctgcg ccttcccgcc aggcctggac      120

actggttcaa cacctgtgac ttcatgtgtg cgcgccggcc acacctgcag tcacacctgt      180

agccccctct gccaagagat ccataccgag gcagcgtcgg tggctacaag ccctcagtcc      240

acacctgtgg acacctgtga cacctggcca cacgacctgt ggccgcggcc tggcgtctgc      300

tgcgacagga gcccttacct cccctgttat aacacctgac cgccacctaa ctgcccctgc      360

agaaggagca atggccttgg ctcctgagag ggcagcccca cgcgtgctgt tcggagagtg      420

gctccttgga gagatcagca gcggctgcta tgaggggctg cagtggctgg acgaggcccg      480

cacctgtttc cgcgtgccct ggaagcactt cgcgcgcaag gacctgagcg aggccgacgc      540

gcgcatcttc aaggcctggg ctgtggcccg cggcaggtgg ccgcctagca gcaggggagg      600

tggcccgccc cccgaggctg agactgcgga gcgcgccggc tggaaaacca acttccgctg      660

cgcactgcgc agcacgcgtc gcttcgtgat gctgcgggat aactcggggg acccggccga      720

cccgcacaag gtgtacgcgc tcagccggga gctgtgctgg cgagaaggcc caggcacgga      780

ccagactgag gcagaggccc ccgcagctgt cccaccacca cagggtgggc ccccagggcc      840

attcctggca cacacacatg ctggactcca agccccaggc cccctccctg ccccagctgg      900

tgacaagggg gacctcctgc tccaggcagt gcaacagagc tgcctggcag accatctgct      960

gacagcgtca tggggggcag atccagtccc aaccaaggct cctggagagg gacaagaagg     1020

gcttcccctg actggggcct gtgctggagg cccagggctc cctgctgggg agctgtacgg     1080

gtgggcagta gagacgaccc ccagccccgg gccccagccc gcggcactaa cgacaggcga     1140

ggccgcggcc ccagagtccc cgcaccaggc agagccgtac ctgtcaccct ccccaagcgc     1200

ctgcaccgcg gtgcaagagc ccagcccagg ggcgctggac gtgaccatca tgtacaaggg     1260

ccgcacggtg ctgcagaagg tggtgggaca cccgagctgc acgttcctat acggcccccc     1320

agacccagct gtccgggcca cagaccccca gcaggtagca ttccccagcc ctgccgagct     1380

cccggaccag aagcagctgc gctacacgga ggaactgctg cggcacgtgg cccctgggtt     1440

gcacctggag cttcgggggc cacagctgtg ggcccggcgc atgggcaagt gcaaggtgta     1500

ctgggaggtg ggcggacccc caggctccgc cagcccctcc accccagcct gcctgctgcc     1560

tcggaactgt gacaccccca tcttcgactt cagagtcttc ttccaagagc tggtggaatt     1620

ccgggcacgg cagcgccgtg gctccccacg ctataccatc tacctgggct tcgggcagga     1680

cctgtcagct gggaggccca aggagaagag cctggtcctg gtgaagctgg aaccctggct     1740

gtgccgagtg cacctagagg gcacgcagcg tgagggtgtg tcttccctgg atagcagcag     1800

cctcagcctc tgcctgtcca gcgccaacag cctctatgac gacatcgagt gcttccttat     1860

ggagctggag cagcccgcct agaacccagt ctaatgagaa ctccagaaag ctggagcagc     1920

ccacctagag ctggccgcgg ccgcccagtc taataaaaag aactccagaa ca             1972


<210>  818
<211>  3288
<212>  DNA
<213>  homo sapiens

<400>  818
gctccctccc ctcctagctg gcttcggcgg ggacggcggc ggcggcggcg ggcggggagg       60

gcgtgcgccg gccgagaggt gtcggcggcg aggcaaagga agtttcaagt ggaaggtcgt      120

ccgtcggccg gcgcgtcctc ctgctctcct ccgcagcatc atggcggagc cgagcggctc      180

gcccgtgcac gtccagcttc cccagcaggc ggccccggtg acagcggcgg cggcggcggc      240

cccggcggcc gcgacagcag cgccggcccc ggcagctccc gcggccccgg ccccggcccc      300

ggccccggcg gcacaggctg tcggctggcc catctgcagg gacgcgtacg agctgcagga      360

ggttatcggc agtggagcta ctgctgtggt tcaggcagcc ctatgcaaac ccaggcaaga      420

acgtgtagca ataaaacgga tcaacttgga aaaatgccag accagtatgg atgaactatt      480

aaaagaaatt caagccatga gtcagtgcag ccatcccaac gtagtgacct attacacctc      540

ttttgtggtc aaagatgaac tttggctggt catgaaatta ctaagtggag gttcaatgtt      600

ggatatcata aaatacattg tcaaccgagg agaacacaag aatggagttc tggaagaggc      660

aataatagca acaattctta aagaggtttt ggaaggctta gactatctac acagaaacgg      720

tcagattcac agggatttga aagctggtaa tattcttctg ggtgaggatg gttcagtaca      780

aatagcagat tttggggtaa gtgcgttcct agcaacaggg ggtgatgtta cccgaaataa      840

agtaagaaaa acattcgttg gcaccccatg ttggatggct cctgaagtca tggaacaggt      900

gagaggctat gacttcaagg ctgacatgtg gagttttgga ataactgcca ttgaattagc      960

aacaggagca gcgccttatc acaaatatcc tcccatgaaa gtgttaatgt tgactttgca     1020

aaatgatcca cccactttgg aaacaggggt agaggataaa gaaatgatga aaaagtacgg     1080

caagtccttt agaaaattac tttcactgtg tcttcagaaa gatccttcca aaaggcccac     1140

agcagcagaa cttttaaaat gcaaattctt ccagaaagcc aagaacagag agtacctgat     1200

tgagaagctg cttacaagaa caccagacat agcccaaaga gccaaaaagg taagaagagt     1260

tcctgggtca agtggtcacc ttcataaaac cgaagacggg gactgggagt ggagtgacga     1320

cgagatggat gagaagagcg aagaagggaa agcagctttt tctcaggaaa agtcacgaag     1380

agtaaaagaa gaaaatccag agattgcagt gagtgccagc accatccccg aacaaataca     1440

gtccctctct gtgcacgact ctcagggccc acccaatgct aatgaagact acagagaagc     1500

ttcttcttgt gccgtgaacc tcgttttgag attaagaaac tccagaaagg aacttaatga     1560

catacgattt gagtttactc caggaagaga tacagcagat ggtgtatctc aggagctctt     1620

ctctgctggc ttggtggatg gtcacgatgt agttatagtg gctgctaatt tacagaagat     1680

tgtagatgat cccaaagctt taaaaacatt gacatttaag ttggcttctg gctgtgatgg     1740

gtcggagatt cctgatgaag tgaagctgat tgggtttgct cagttgagtg tcagctgatg     1800

tatgtccctt gatgtcaccc tgatctgtca tgccccaccg ccacccctac tcccttcaac     1860

cctccctctt tctgcccatt tcctcccacc ccctcactcc catttcctag caaaatcaga     1920

agattgtgaa gaggccggct tcaacaaaat gggataaaaa aataattttt taaaacttac     1980

aacactccga gttctgcttt attctctagc aatccacagt acaagaacaa gcaaatgcca     2040

cagctgcacg actgttgctc atttttccaa aagctattta atattcttag caatcaattt     2100

ggatatccct taagtgaaaa gaatctgaaa tacactcagg tggtcttatt tattggcaac     2160

aaaaggaatt ttctatccag aagcctattt ctcctttcat tgttgttatt tctgttataa     2220

tactttaatt gtacatctga caatactgcc tcttttatgt tgtatttaga aattaatata     2280

cttataaaat taagatttat tagccaaact tgaattctag ttttaaaact gactgtgaat     2340

tttatttttc atatatttat gcattacaca ccttagctat aagaaaaaaa gggttttgat     2400

tatatgcttc ttgcagttaa tctcgttatt taaacaaaaa gttttgggtc tgtctttgga     2460

gtatttgtaa cttctaaatt ttgaaatgac tgaattagga atttggatgc ttattctttt     2520

agtctgtttg cctaaaaacc aatttacaat ctgactgtct cttgggagag ggaggtgcct     2580

tgcaaacttt cacattaaga atgtgcctga ggctgcttta ctctggaata gtctcagatc     2640

taaaatttcc tctatataag gtggcatatg ttaagttttg cttcattgga ccgtttagaa     2700

tgctatgtaa aatgttgcca ttctgttaga ttgctaacta tatacccatc tctgatttgg     2760

ctctccttaa gtgataggat ttgttattct aaaggtgata aacttgaaaa tatcagaatc     2820

tgagttttac ttgaaatttt gcagaatacc caggtggagt gaaaattgga agggttttgt     2880

gcaatgacta aaaggtaaaa cgctgttaag gttcaagaat caatactttc aacccaagta     2940

gccctctgct tgactgtata ttatggaact agtaaacctt aggattttga aaattggagt     3000

ctaatctttc aaggaggtgg gctcccagga tggtaccatt gctctttcct agctaaccct     3060

agatatggca gctctttaat gtacttcaaa aagcaaatat atattactaa ggaaaaaaag     3120

ttatttataa ttgccttgtc ataattgtta aggtgttcta gagccatttg catacaattt     3180

aatgtaattt cattccattc tattgtttac acaacgatta ctcgaagatg actgcaaagg     3240

taaaaggaaa ataaaagtgt attgcacaat gagaaaaaaa aaaaaaaa                  3288


<210>  819
<211>  354
<212>  DNA
<213>  homo sapiens

<400>  819
atgtctggcc gcggcaaagg cgggaagggt cttggcaaag gcggcgctaa gcgccaccgt       60

aaagtactgc gcgacaatat ccagggcatc accaagccgg ccatccggcg ccttgctcgc      120

cgcggcggcg tgaagcgcat ctccggcctc atctacgagg agactcgcgg ggtgctgaag      180

gtgttcctgg agaacgtgat ccgggacgcc gtgacctata cagagcacgc caagcgcaag      240

acggtcaccg ccatggatgt ggtctacgcg ctcaagcgcc agggccgcac cctctacggt      300

ttcggtggtt gagcgtccct ttctatcaac aaaaggccct ttttagggcc ccca            354


<210>  820
<211>  1779
<212>  DNA
<213>  homo sapiens

<400>  820
aggcgggccg cggcggcggc gggcagcgga cgggcggact gacgggcgcc tccaccttgc       60

tccctccctg gctgccggct tccttttgtc tttctgggcg gcgatgagcg cagggccggc      120

gcagcagctg cgggcgcacg gaggcccgcg ctgctagtca ctcctcccgg cctcggcgcg      180

cttgtcccgg gcagcggccc gggcccgctg cagccgccgc cggcgccgaa cttgggctcg      240

ggaagccggc ggaccgcgtc ctgcgccgga gcaggggcat ggtctagtgg cccagtcagg      300

acgcggaaac actccctgga ggttctgacc cactccctct cagcctccgc ctggtctctg      360

gtgtagtcgc cgccgccagc cgccatgggc aaacagaaca gcaagctgcg gcccgaggtg      420

ctgcaggacc tgcgggagaa cacggagttc accgaccacg agctgcagga gtggtacaag      480

ggcttcctca aggactgccc caccggccac ctgaccgtgg acgagttcaa gaagatctac      540

gccaacttct tcccctacgg cgacgcttcc aagttcgccg agcacgtctt ccgcaccttc      600

gacaccaacg gcgacggcac catcgacttc cgggagttca tcattgcgct gagcgtgacc      660

tcgcggggca agctggagca gaagctcaag tgggccttca gcatgtacga cctggacggc      720

aacggctaca tcagccgcag cgagatgctg gagatcgtgc aggccatcta caagatggtg      780

tcgtctgtga tgaagatgcc ggaggatgag tccaccccgg agaagcgcac agacaagatc      840

ttcaggcaga tggacaccaa caatgacggc aaactgtcct tggaagaatt catcagaggt      900

gccaagagcg acccctccat cgtccgcctg ctgcagtgcg accccagcag tgccagtcag      960

ttctgagcga gcggcccctg gacagttgca gagaaacaca ggcttgtcgt gccgtttaag     1020

ctttgcttgc aagagtggat gccccgcaat cgttcctgct ctcccgggcc ccgggcctgg     1080

ggcatgcgtt gcacctgccc agcccggtgg ctgcgcctcc ctcctccacc tgaccaacgc     1140

gacattcctc ccctcacgcc tggcccggtc ccttccaggg caactcccag ggatgtggtg     1200

acatgcaggg ttcaagtgtt cttggttcca ggcacctccc ggctcacggg gagctcagag     1260

gtccatgccg aggagaccag gcaggacctc ccgaggctgc gccccggccg gcccatgcgt     1320

tttgtgatcc caagtgactc tgtgggaagg gtggggacga ggcgtcggga gggtatacag     1380

ggagcccctc ccgtgcatgg ctgccccccc gttcattttc tccaccacag ccgcttgcac     1440

gtatagatac tgtggtcccc tttcttttaa tatataaatt atgtatggtg aagtggagtg     1500

tattgtgtag gtcccgtatt taatgcctct gactgccttt gaagcgcagc cctctgtggc     1560

ccgcagcccc ctgagcctgg ctgttgtgtg gtatttatgc tctctttgtc tgcctgtttc     1620

taaggaaatg catgtgtgcc ctgagccgtg atgatcctcc catccgtgtt gtgagcacag     1680

gcatttgtgt ctggtctgtc ctccctgttg attggtctgg catttccggt attaaaatga     1740

taaaataaat ggcattttct gaaaaaaaaa aaaaaaaaa                            1779


<210>  821
<211>  6186
<212>  DNA
<213>  homo sapiens

<400>  821
ctctcttcct cccttcctag agagggaaca acattcatgt gacgggcccc tctgcttctc       60

ccccgcccca tcatctccag cgcgtggtgg gggaactgct ggggaaggcg attggcatcg      120

atctctccat cccttccgag gcccgacttc ggtggccacc gagtactaaa ttcacttggg      180

aataaaagaa aaacataaga aaattataag agaaaggaat tgtcttagaa gaaagaaggc      240

aagccaccat tttacccacg taaatatatg aatatatttc tgacattgag gtgttccaga      300

agatgataaa gaaatgatag cagctccaga aataccaact gattttaatc tactacagga      360

gtcagaaaca catttttctt ctgacacaga ttttgaagat atcgaaggaa aaaaccaaaa      420

gcaaggcaaa ggcaaaactt gtaaaaaagg caaaaagggc ccagcagaaa agggcaaagg      480

tggaaatgga ggaggaaaac ctccttctgg tccaaaccga atgaatggtc atcaccaaca      540

gaatggagtg gaaaacatga tgttgtttga agttgttaaa atgggcaaga gtgctatgca      600

gtcggtggta gatgattgga tagaatcata caagcatgac cgagatatag cacttcttga      660

ccttatcaac ttttttattc agtgttcagg ctgtaaagga gttgtcacag cagaaatgtt      720

tagacatatg cagaactctg agataattcg aaaaatgact gaagaattcg atgaggatag      780

tggagattat ccacttacca tggctggtcc tcagtggaag aagttcaaat ccagtttttg      840

tgaattcatt ggcgtgttag tacggcaatg tcaatatagt atcatatatg atgagtatat      900

gatggataca gtcatttcac ttcttacagg attgtctgac tcacaagtca gagcatttcg      960

acatacaagc accctggcag ctatgaagtt gatgacagct ttggtgaatg tggcactaaa     1020

tcttagcatt aatatggata atacacaaag acaatatgaa gcagaacgga ataaaatgat     1080

tggaaaacga gccaatgaga ggctagaact cctgctacaa aagcggaaag agcttcagga     1140

aaatcaagat gaaatagaaa atatgatgaa tgcaatattt aaaggagtgt ttgtacatag     1200

ataccgtgat gcgatagctg aaattcgagc tatttgcatt gaagagattg gcatttggat     1260

gaagatgtat agtgatgcct ttcttaatga cagttattta aaatatgttg gttggactat     1320

gcatgataag caaggtgaag taagactcaa atgtcttact gctctacaag ggctttatta     1380

taacaaagag cttaattcca aactggaact ttttaccagt cggttcaagg atagaattgt     1440

gtctatgacc cttgacaaag aatatgatgt tgcagtacaa gcaataaaat tactcactct     1500

tgttttacag agtagtgaag aagttctcac tgcagaagat tgtgaaaatg tctatcatct     1560

ggtttattca gctcaccggc cagtagcagt agcagctgga gaatttctct acaaaaagct     1620

cttcagtcgt agagatccag aggaggatgg aatgatgaaa agaagaggaa gacaaggtcc     1680

aaatgccaac cttgttaaga cattggtttt tttctttcta gaaagtgagt tacatgagca     1740

tgcagcatac cttgtggata gcatgtggga ctgtgctact gagctgctga aagactggga     1800

atgtatgaat agcttgttac tggaagagcc acttagtgga gaggaagcac taacagatag     1860

gcaagagagt gctctgattg aaataatgct ttgtaccatt agacaagcgg ctgaatgtca     1920

tcctcccgtg ggaagaggga caggaaaaag ggtgcttaca gcaaaggaga agaagacaca     1980

gttggatgat aggacaaaaa tcactgagct ttttgccgtg gcccttcctc agttattagc     2040

aaaatactct gtagatgcag aaaaggtgac taacttgttg cagttgcctc agtactttga     2100

tttggaaata tataccactg gacgattaga aaagcatttg gatgccttat tgcgacagat     2160

ccggaatatt gtagagaagc acacagatac agatgttttg gaagcatgtt ctaaaactta     2220

ccatgcactc tgtaatgaag agttcacaat cttcaacaga gtagatattt caagaagtca     2280

actgatagat gaattggcag ataaatttaa ccggcttctt gaagattttc tgcaagaggg     2340

tgaagaacct gatgaagatg atgcatatca ggtattgtca acattgaaga ggatcactgc     2400

ttttcataat gcccatgacc tttcaaagtg ggatttattt gcttgtaatt acaaactctt     2460

gaaaactgga atcgaaaatg gagacatgcc tgagcagatt gttattcacg cactgcagtg     2520

tactcactat gtaatccttt ggcaacttgc taagataact gaaagcagct ctacaaagga     2580

ggacttgctg cgtttaaaga aacaaatgag agtattttgt cagatatgtc aacattacct     2640

gaccaacgtg aatactactg ttaaggaaca ggccttcact attctgtgtg atattttgat     2700

gatcttcagc catcagatta tgtcaggagg gcgtgacatg ttagagccat tagtgtatac     2760

ccctgattct tcattgcagt ctgagttgct cagctttatt ttggatcatg tcttcattga     2820

acaggatgat gataataata gtgcagatgg tcagcaagag gatgaagcca gtaaaattga     2880

agctctgcac aagagaagaa atttacttgc agcattttgt aagctaattg tatatactgt     2940

ggtggagatg aatacagctg cagatatctt caaacagtat atgaagtatt ataatgacta     3000

tggagatatc atcaaagaaa caatgagtaa aacaaggcag atagacaaaa ttcagtgtgc     3060

taagaccctt attctcagtc tgcaacagct ttttaatgaa atgatacaag aaaatggcta     3120

taattttgat agatcatcct ctacatttag tggcataaaa gaacttgctc gacgttttgc     3180

tttaactttt ggacttgatc agttgaaaac aagagaagcc attgccatgc tacacaaaga     3240

tggcatagaa tttgctttta aagagcctaa tccgcaaggg gagagccatc cacctttaaa     3300

tttggcattt cttgatattc tgagtgaatt ttcttctaaa ctacttcgac aagacaaaag     3360

aacagtgtat gtttacttgg aaaagttcat gacctttcag atgtcactcc gaagagagga     3420

tgtgtggctt ccactgatgt cttaccgaaa ttctttgcta gctggtggtg atgatgacac     3480

catgtcagtc attagtggaa tcagcagccg ggggtcaaca gtacggagta aaaaatcaaa     3540

accatctaca ggaaaacgga aagtggttga gggcatgcag ctttcactca ctgaagaaag     3600

tagtagtagt gacagtatgt ggttaagcag agaacaaaca ctgcacaccc ctgttatgat     3660

gcagacacca caactcacct ccactattat gagagagccc aaaagattac ggcctgagga     3720

tagcttcatg agtgtttatc caatgcagac tgaacatcat caaacacctc ttgattataa     3780

cacgcaggta acatggatgt tagctcaaag acaacaagag gaagcaaggc aacagcagga     3840

gagagcagca atgagctatg ttaaactgcg aactaatctt cagcatgcca ttcggcgtgg     3900

cacaagccta atggaagatg atgaagagcc aattgtggaa gatgttatga tgtcctcaga     3960

agggaggatt gaggatctta atgagggaat ggattttgac accatggata tagatttgcc     4020

accatcaaag aacagacgag agagaacaga actgaagcct gatttctttg atccagcttc     4080

aattatggat gaatcagttc ttggagtgtc aatgttttaa taccagtaca caattaaatc     4140

tgtggtgaag tcattttcta agtggaagag gaaattttaa agtgtggtag atacagtgaa     4200

attctgtaca gatttttctc taaggagaat atgacatgct tatgcttacc aagatcaagt     4260

gcattgaggg gcagttttgt ttgcctgaat aaacgtaaag gacaagtaaa caatttgatg     4320

ataagctaca gtttttctta gaaagtaaat attttattta tgcgctgtta gttggctttt     4380

gaatcgatta tttcatgctt ttttttaaaa aaaaaaaaaa acaaaataac aatctgaaga     4440

ggcatttggt acagatatga attctcttac atttatttac tggttgtact aaataatgat     4500

gacctctgct ggatttctgt ttacatccag aaaacaatgt taaggatgta tttattcccc     4560

taccctgaag aaagtgtagg atagaattgt ttttagcatt ctaaatttaa atgcttaaaa     4620

cgtcaatcaa caaaactttg ttttaaatat tgtaattgtg gagaaaagta aacttataag     4680

cagaactttt acaatttttt catctaaaag tattttaaga tatttttaaa atccaagagc     4740

ttctctatac ttttcagaaa tatccagatg cagtgaactg ccagaaggta accagtctca     4800

aacatgctta tcccattatc aaccctgaaa gtttgcttgt cctttaagat aaaaatgtaa     4860

tgttgtgata ttccttccag taatgccact gtattttgtc tccaaataaa agaagcttat     4920

tgtagtatgt ttgcagaaaa attctaaaca aaaattatac agcttattag agtgtgggaa     4980

tagggatcta aattttaaat aaaattatat atatatataa attggtgctg attttataat     5040

tgcgcagttt gtttagtttt ttcttacttt taaattccaa cttaaaatta tgaggtttca     5100

gaaatatatt gaaagtttaa caatgtttaa aaatagaaaa gcatgagtgt tcatgcttta     5160

aaatgatttt taaatttgta ttttatattg ttttatctat ctgtctttgc aagcagtctt     5220

caggttaaag atacttctaa caggttacag tacatttcct ctgtatgtaa attagatggg     5280

ataatagaat tcataaccca taatattctt tgaaagctaa gctttaaact tcattttatg     5340

tcctttcaca aataaattag tttaaaacag aaagtggcta cttgccattt tgacatcaac     5400

tcattttgcg aggcttaggc agctagacat cgtttaaaac aaaatattaa cttatattac     5460

atgtgtatct atctattgtc agtcgtctct cagttcttga ggtatattat tttaatcatt     5520

ccatgcctta atatgcttgc aatacaagaa tatcttcaga tgggtgaata ccaaaaggct     5580

ttcagttttt agtcagaaat caagcattgg gctgtggtag ccaaaaacca taggttagct     5640

aaaaagatca tgatacaatt attttattaa gtcatggtta ataacaaatg aatccagact     5700

tgtctaacag attttccatc aacaaatatt gttatgtgca aaagtattgc ctatgttgtt     5760

ttacacacca ctgcattaac tagaactgct gagaggactg tatatatgat tttaaaccta     5820

agttgatttt ttttctcact cttgaaagga gtacttcttt gtgaaagcag ttcttacagc     5880

tttgttttca accagctaaa aatgttttat atattactct aacctgttgt cctccacatt     5940

ctattgtcct aattgtactg ttttctgatt tgtatttatg tcttgagaca gtaacttttt     6000

gaataaaaat aaacctacag tatgttgtat gttttctctt gtactcaaag ggggagggtg     6060

gctataaatg gtttgcaaat ttatatctat tatcacatct tttaatgtgt ttggggaata     6120

atttatagag aataccatca gtttatattt ttaataaatc atatgtattt acaatgaaaa     6180

aaaaaa                                                                6186


<210>  822
<211>  9256
<212>  DNA
<213>  homo sapiens

<400>  822
gaggagaggg cgcgttagtg agcagcgact gtggcattga tgtttgagca tacttctgaa       60

ctggcttttg ttgagactat cagtatagaa gcatgcgctg tcccaaatcc gctgttacta      120

tgagaaatga agagctgctt ttaagtaacg gcacagccaa caagatgaac ggagctttgg      180

atcactcaga ccaaccagac ccagatgcca ttaagatgtt tgtcggacag atcccccggt      240

catggtcgga aaaggagctg aaagaacttt ttgagcctta cggagccgtc taccagatca      300

acgtcctccg ggaccggagt cagaaccctc cgcagagtaa aggttgttgt ttcgtaacat      360

tttatacaag aaaagctgca cttgaggccc agaatgcact gcacaatatt aaaactttac      420

ctgggatgca tcatcccatt cagatgaaac ctgcagatag tgaaaagtcc aacgctgtgg      480

aagacagaaa attgttcata ggaatggtat cgaagaaatg taatgagaac gacatcaggg      540

tgatgttctc tccatttggc cagatagaag aatgccggat cctccgggga cctgatgggc      600

tgagtcgagg ctgtgcgttt gtcacatttt ctacaagggc aatggcacag aatgcaatca      660

aagccatgca tcagtctcag accatggagg gctgctcttc acctatcgtg gtgaagtttg      720

ctgacactca gaaggacaaa gagcaaaggc gcctccagca gcagctcgct cagcagatgc      780

agcagctcaa cactgccacc tgggggaacc tgacagggct gggcggactg accccacagt      840

atctggcgct cctgcagcag gccacctcct ccagcaacct gggtgcgttc agcggcattc      900

aacaaatggc aggcatgaat gctttacagt tgcagaacct ggcgacgctg gctgctgctg      960

cagctgcggc ccagacctca gccaccagca ccaatgcaaa ccctctctct accacgagca     1020

gcgccctggg agccctcacg agtcccgtgg ctgcttcaac ccccaactcc actgctggtg     1080

cagccatgaa ctccttgacc tctctcggga ctctgcaagg actggctgga gccactgttg     1140

gactgaataa tattaatgca ctagcaggta tggcggctct gaatggagga cttggcgcca     1200

caggcttgac gaatggcacg gctggcacca tggacgccct cacccaggcc tactcaggaa     1260

ttcaacagta cgcagccgcc gcgctgccca ctctgtacag ccagagcctg ctgcagcagc     1320

agagcgctgc aggcagccag aaggaaggtc cagagggggc aaacctcttt atttaccacc     1380

ttccacagga atttggagac caggacattc tgcagatgtt catgcctttt ggaaatgtta     1440

tctctgctaa agtcttcatt gacaaacaga ccaatctgag caagtgcttt ggttttgtta     1500

gctacgacaa tccagtctct gcacaagctg ctatccaagc tatgaatggc tttcagatcg     1560

gcatgaaacg cttgaaggtg cagctgaagc gttccaaaaa cgacagcaaa ccttactgat     1620

cctaacccca gaggctccct gctctcattt tagctttctt agggtaagtc ccacgagcca     1680

gcctgtctca acagggaagg cagaggagga ccacattgcc aacttttacc aagagagacg     1740

gttattttta caataaggcc tccatgtccc cacccacttc ccctacccag tttgccataa     1800

ttaaaacttg ggctactttg tttctattga gtaattcctc ctccagttgt gccactgtat     1860

tctcctttgt tttgcgattt gaatctcctt ttaccttttt ttttaatttt tttcattttt     1920

gctttttttt aaagagaagc atatacacaa ataaatggca tcttgagaat ttaaaaggca     1980

aacaaacaaa cgctaatgtg caattctaac tctgaaacca ctggtgcccc gagagcactg     2040

cctggagaat tcacccctcc ttgcccggcg cccgcccccg gagggagggc ccggtgctta     2100

gaggttaact tggtggccta ggagagggag aagccaggag aagcacttac tccaaccaca     2160

cgtctttcca ctacatcggc ttgttttact aagtaggatt ttattttagg gttcaaagaa     2220

acatgacatt tattggtcaa aatattacac tggttgtcta ttttgttatt gttttatttt     2280

agtttttaga aaggattaat gtacaaaaag atttagagat ctgtttctta aagctacagg     2340

gtttaaaaaa taaaaatgag tgaaaatact tgatgtttct tgaaagataa atttaataat     2400

aataaataaa tacataaata cataaataaa aaagaaagcc acaggcctgt aaattttatt     2460

tgtaaaaaag catttctatt tttatacaaa atttttactg cctcagaaat aatggaagtt     2520

atttattgcc tattgttaac ttattgggta cctaaagagc agttctctgt ctagctagaa     2580

ccttctgaag tagtctctag aggaattgtt ctaggaatgg gctttttttc accgttgaac     2640

cctagacctg aagttcatgc tttatcctct cgttgtttgt atctgtctga ttattttgtt     2700

tgtaacttcc attatctagt ttacagttca gtcgtctgac tttccccgta tgtcacattt     2760

gttgaaactg gaccttctcc ccctgtccct caccccaaaa cacccggaat ccatcccctt     2820

tcgctctctc cagatggatt ctcttggggt ttcattgtgc tgtggataag gagtgtaaga     2880

aatgcaaatt atgtgaatgg ctcggagact ccctaatgac ctaagatttg cattagtttt     2940

tctcctgcac ccttaaaagt gattttgttg ccgctgcata gattctgtgt aactttttac     3000

tcttccttgt tttttcccta gacatcttca tgcccgttag ttcatcgttt gcctagcatg     3060

tccctgtggc gtctcaaaaa aaagtttcat cgtcccgtca ttgtttctga tgtctttctg     3120

acctcacatc atatttggtt ctcctactga cctttgatct agtttgacct ttgaaatttg     3180

catgtgacct catctagcta tgaattctgg gaagtcaatg tgaaaaacat tgctgcattc     3240

atgcaagact gaaatttatt attagacaaa ttcattatag aaaaaacctg tggcaaaaac     3300

gtttctttct tatttttttt cttttcctaa aacagacttg aaagtattat acagggattg     3360

gcattcttcc cggtcactgg taacaatagc aatatgtgtc cagggacaca gaatgttggt     3420

ttctaacaga ctacttccaa aaacagtttg agaaaaaaac tgtctgattt taagtctcta     3480

gaggtctgta atagttttta catttttcag gcagtgtaaa gttttttgat aaggccattt     3540

taggtggctc actttctcat taagatatat atatagaacc actttttgta gattagtata     3600

agaaaaatat ttaccctgtt ttggggcaaa tgctacctat ttgtgtcacc ttttgctgaa     3660

ctcacagtta gacaatccat ggtttaatgc acatgaaatt acctatattt tatactgttt     3720

caatgtacag gagaaaggtt actgtaaact gtgttatgtt ggtgcttctg tgaattaagt     3780

tgtggtttca tcatgagtct taatgttctt tgttgataag acaagtttag aattggttta     3840

cttaatacaa aaaaaaaaaa aagaatttca aaaaaaaaag ttgtttgctt aaaaaaaatt     3900

tcatgtgagg gaaaaaaaaa aaacctattc cagaataagt tttgtgttgg cttgtgaagc     3960

attgatgtca ttttttttaa ttgtggacta tttagatgtg tttgtgttca gcaaaatgtg     4020

atctgttttt ttcttttaaa gaaaaaaagt gaaaatatat agtgccaaat tccaaaggta     4080

cttccttcct agagcttcag tgtgtttctt gtgagaagta atttgataac atgggtattt     4140

tattatgtgt tttgtataaa tccctaatat ttaaaaaaaa aaacaaaaca aaaaaaggtt     4200

acaaagtttg ttaacttgct atcctgtggt cttgttgcct gaaattgtta ttgtttgtta     4260

tttctctctg atgttttttg taagacattg tataagtgcc catgtcccac ttttttaacc     4320

actccgcaca tcagtgctgt gaaggcaacc tcaccatgta ttttcttcat aatctatgga     4380

aacctctaag gtgagaaagt tttgaacttt taaccctttc tacccagagc tatctggaat     4440

gttgatgact ttttatactg tcatgatttg agtttgtttt ggggtgtttc caatttggat     4500

ttttttccct gcatctatcc tctaagttgt ttcggtttga ctactttgtt ctttggttaa     4560

gatccaaaag aaaacagaaa acaattccac gaggccaatc taaagggaaa aaatcctaca     4620

ctacttttac tacttttgat tatttctcat ttttgggaaa agaattccta atgtgctact     4680

agaattcctt cttcagtttt aacgagtaat tggataaacc ctgagggaaa acggaggtag     4740

attcagcacc taacaatcct gtatgctttt gagatcacgt ttagtgctat gtcctagtct     4800

agaatatttt catatacctt gcagtaaaac gactttgtgg caggacagtc tcttgagggg     4860

ttttgtttct gtttcctaaa tactcctaaa taatatttct aatcagccat tatgctgggg     4920

catctctgat cccagtaggt acctctgaat ataccaggtg tctggagtta gaagcccata     4980

gccctttccc agcctttttg gtttttttaa ttgaacacat ttcatctaag taaagctcag     5040

ttctttatca caatttactg accaaatacc tagcaccagt tcctgctgcc actttttaaa     5100

gtgccatatg actttctacg aacaggtacc ttgctgtctt gacaaatcct aatgtcacgc     5160

ctacagcccc aacacaagct ccagtcttcc tcttcggcat gccctggaag cttcttggcc     5220

tcagctcccc ttccccgctc agcaccctgt taggatcagt gtgtgtggat gggatagccc     5280

tgggatggaa aggactagcc tctactgatg caaaaaaaca aaaagcaaca caaacgtttc     5340

cttcttatag cacatgcact tccttacaat gacatgattt gtattatcct cacatgtgtt     5400

tactactgct ggggccttcc ttcatcctct gagggctatt ttgtactttc tgcagcaatc     5460

agcttaataa caacacttat tgcacctgtc tctctctgag aacacggtgt gtctcgacac     5520

gtaccacgta cgtggaaaca caagagccca ccacttgaat ttctaagacc atttcattct     5580

gaaacttctt atcaattacc taaatctcaa cgaaaaacaa tttactgaag ccgactcccc     5640

tccccatctc cctctcaacc tcaacccacc tgcatgcatc tcccccagag gaaacactga     5700

gggtagggga caggaggctc aggacgcgcc ctctgaatcg agtgtttctt cttcacaagt     5760

caccaagaga ggacatgagg gggaaagtcc ttttttgccc ttctccaaaa aataaccttc     5820

cacagagaca aactgtcctt ctatccactt ttatctttta ataaatatca aaaggaaaaa     5880

gctgcaaggg tgcaaagggc ctgtgccaga agaaaacaca cacagggaaa ccgctttttt     5940

taatcaattg tagagaatag tcatttttaa tctaaattag agaattgtga tacaatggca     6000

gtcctcaaag gcgtaacgag ttcatctttc tttcaccata ggggttatag ttggcttgtg     6060

ctactctgga atcattttac tgtttgtttt tattatctta agtgctaatt aaaaaaaaaa     6120

taaaatttta aaaaaacctg tagtttcatt acctttttga ataatgtcat acaaaaaatg     6180

tatttgtttt tttgtgctgt gagaattgat gtttgtagat taataatcat tttgtttaga     6240

attacaaaat agtttttaaa tattgtctga gaaaagccaa agttaatgca acctagtgga     6300

aactgtaaga ccatttgagt attgtttgtt ttattgatgc atttggattt tgttgtttga     6360

tggaatttga gccaaaaaaa aaatacgcag gctttcctat ttctacaact gattgtactt     6420

atgcattttg taccagtgga actttttata ctggagatta aaaaaaaaat ggaaattttt     6480

gtggcttgct ctggtgggcc cctgacaatg actgatttca agtttgattt cgggttgatt     6540

gattgattga ttgatagaaa gaaagttgct tttcttttga gaattaaaaa ctttggcttg     6600

atttcttttt tccctttgct tatatctagc attagaattt tgtcttaaaa taacagcggt     6660

aagtttcact ttttattctg tattgtgcag ttacacaata aggtaattag atttagaagt     6720

actcagtcac tttaagtgga taaatgtatt agttaaaact ttagggtttg cttttttgct     6780

gtttagatca aagttttttc tgattcttct gtcctcattg tgaacataac cgtgtagttg     6840

aaacagtcaa acttattttt gtaatgtatg ttattgtgtg atgcagtttt ttgcttctgt     6900

ctccaatatt aaaccatttt cctaatactt gtttctctct ctgcgtgttg tattgttggt     6960

agtcattata tgttggtgat acatctgcac acctcactgt ttcacgtatc tgtttttttc     7020

tctatgttgt gtaaaaagat acagtcgatt ccacttaagt gaatatctga tttggggaag     7080

aggaaactgc acagcagcca cctttgattt atgtacaacc gcccacttga actcctgctt     7140

ccaagattta tacacttttt tcctacagtt cacctcagta actgcctttg gggttggatt     7200

tgccaaggtg ttttacggtc ttttgaccac acaggttaat ttccccttct ctcccctccc     7260

tcatgagtct atccacgcag ttcttaacat acattccaaa ctgctgcggg gtttcctctc     7320

cacacccacg aggccaaacc cgcatcatta cagtccaact cttcttagac actaatcact     7380

ttctaaaaga agtgagttct ccagggaaga aaaatcaact tagccagtga aaagggttaa     7440

acttaagtct attatttgtt gccctcaatc aaaagatatg tatagaaaag tcatttaaat     7500

tatttatttc tacaagctaa ttgaatccag gagcagcttt aattattaac actaacggaa     7560

gagaaaagaa gtatttccaa gggctcaaat ggaagctgta ctcagtccgg tggaggcagg     7620

gggaggtaaa gtttctcaca ctcaagtcgt cttcatagtt tactgtcctt ttccaaacaa     7680

aagctaataa cgccatacgc atccacacac tccctcctgg atgaacctaa gtctcgtccc     7740

cactgtcacc ccaaggccag ttatcaaaaa ctgttccttc tctgccctca aagactgaag     7800

ccgcaggccc tgttctgcct ctgctcagga atctgattgc tcttaaagtg ctcttacaag     7860

attccgtcga tgtttgctcc ctctgtctta tctctccttc cagtattttc agacgcacaa     7920

gctctgactc aggccaccca gcacctggca gccttcctct gcgtgccagt gaaatctctc     7980

ccagtaggtg ctcaggctct tcaccctctc gttgcagcag cccctctggc ccgagattgt     8040

attttctagt ctgctcaaga acagaggggc ctggcgaggt ggaggaaggg aggctccctc     8100

cccggggctg gccgcctcag tgatggtgat gccaccagct ccagcctgca cggatggagc     8160

tcacttccta ccatcacttc tgctttcagt ctcctcatag ccttcggcag tctcctctga     8220

aaacacactg cctacgttag tgggaaagga tggctaaggg tgtgatttct ttttattagg     8280

gaggtgggag ggggatgttg ggaggcatgg ggggtgatta aattatcatt tccaaggtgc     8340

aagtgtttat ttttcaaatc tataagtaca tagttccacc attttggcac aagacaaaat     8400

actcatgcta agcaaaggaa gagaaagaca aagccagttt ttgttgcttt tctaaagcaa     8460

caaataattc tccaaagaag gggatgaaaa tgctagttcc tttaagcact tactgactgt     8520

aaagttggtc cctgcttaaa ttcataccca tagttttgag tcggtatgac accactgcag     8580

tgtgagcaag gtgaatccgt gtgccatgca tggaccacct tgggataccg cagcaccatc     8640

aacatccgcc ttgctgatgg aagccacaca cgctgcccag cccacagcag tcgcacgcag     8700

ccgatgggct cggactctta gctggcaggc taggacacac agtgaacatt aatgtactgt     8760

gaatcgttcc tgataagtga ataaaacatt gtgaccaaac aatcagctta ttcacttatc     8820

aggaatcgac tgttctgcta atttgctgtt gttgtttttc atctctgttg tagttcacta     8880

tttttgctgt gttctgtttt ctcctctcat gcttgggcaa atcactggga atattatctt     8940

catgtgacca tgaaacgttt ctattgagtg aaaatgatat cttaacaaaa tctatgcact     9000

tgctatcagg aacacaatac tggatgtgtc ttatatatat tgaactatat agtactcgat     9060

ttcttaaata aagcttaaga aaggactctg ttgtgtgtaa agttaatgtg attatttttc     9120

aaagcagtgt ttctaagggg tatttttgtt cttttaagtc ttgagtgata caggatattt     9180

ttcattaaaa ttatatcact ggctttatga cttaatattc aataaattga ctttggaaac     9240

aaaaaaaaaa aaaaaa                                                     9256


<210>  823
<211>  6173
<212>  DNA
<213>  homo sapiens

<400>  823
agtgcggctg cgcgtgaggc ggcggcgcgc cggcgcgcga ggggcggggt gaaaggtcac       60

agcgcggcag cgggtctggc tggcggcagc ggcgggaggg agccgagaga cccgagtgca      120

cgtgtggaga agcggcggca caagcgcggc ggcgggagac actcccgccc ccaccagact      180

caagccctca ctcgactctc gcggccttcg ttgctcgcac agctccctgc ccaggctagg      240

aggccggctt gcggggttga gtggcccgag ctaagggtgc ggagacctaa gggcggcgac      300

tacgacggcg ttgatatcgg tggtaacgac ggcctcagca ggcggggaag atgaaaggta      360

gccggatcga gctgggagat gtgacaccac acaatattaa acagttgaaa agattgaatc      420

aggtcatctt tccagtcagc tacaatgaca agttctacaa ggatgtgctg gaggttggcg      480

agctagcaaa acttgcctat ttcaatgata ttgctgtagg tgcagtatgc tgtagggtgg      540

atcattcaca gaatcagaag agactttaca tcatgacact aggatgtctg gcaccttacc      600

gaaggctagg aataggaact aaaatgttaa atcatgtctt aaacatctgt gaaaaagatg      660

gtacttttga caacatttat ctgcatgtcc agatcagcaa tgagtcggca attgacttct      720

acaggaagtt tggctttgag attattgaga caaagaagaa ctactataag aggatagagc      780

ccgcagatgc tcatgtgctg cagaaaaacc tcaaagttcc ttctggtcag aatgcagatg      840

tgcaaaagac agacaactga acaaattaca aatgaacttt cttgcacttg cttgtcgcca      900

aataaaagag aggcccattg attcctcccc caccccaaca cttttctttt aaagcttttc      960

tccctccttg ttcttgtttt tctttcttcc tttccttttc tctgagagtt ttaatacttt     1020

caaggacttt aaaaaaataa tcatgtttga attgttttct cttatttttg tgaggtggtt     1080

tgaaggaagg acaaggtaga tctgtttagt tttgcagttg aagttagatg gtcctaaaca     1140

tttaattgtc aaataatttc aaatttaatg tcctgctttc acattgaagg gcagagccta     1200

caaaacattg tatatttcaa aagacaaaaa gaagcagcag cagtatcttg ttctctaatt     1260

catagacaag ttgagtgtgt ttgtggtact ttgggttttt aaacactttg ggatactaat     1320

ccctagacat tgccttcact ccacctttag tccttctgag cactctctcg ggagttggaa     1380

cattgttatc cttgtaagaa atactaagct tatgttgatt tttaagtaat tatatcttct     1440

cttcttgctg gtgggtgggg cagtttggtt tagtgttata ctttggtcta agtatttgag     1500

ttaaactgct tttttgctaa tgagtgggct ggttgttagc aggtttgttt ttcctgctgt     1560

tgattgttac tagtggcatt aacttttaga atttgggctg gtgagattaa ttttttttaa     1620

tatcccagct agagatatgg cctttaactg acctaaagag gtgtgttgtg atttaatttt     1680

ttcccgttcc tttttcttca gtaaacccaa caatagtcta accttaaaaa ttgagttgat     1740

gtccttatag gtcactaccc ctaaataaac ctgaagcagg tgttttctct tggacatact     1800

aaaaaatacc taaaaggaag cttagatggg ctgtgacaca aaaaattcaa ttactgtcat     1860

ctaatgccag ctgttaaaag tgtggccact gagcatttga ttttatagga aaaaatagta     1920

tttttgagaa taacatagct gtgctattgc acatctgttg gaggacatcc cagatttgct     1980

tatactcagt gcctgtgata ttgagtttaa ggatttgagg caggggtaat tattaaacat     2040

attgcttcta ttcttggaaa aatagaagtg taaaatgtta ataatacaaa tgtcactgtg     2100

acctcctcca ctgagaggac tggtttatgc cagatcattt tccggcacac acggagtggc     2160

tttgacagat tgataacttt gtaagatggg agacatctga aatattcatg ttttcctttt     2220

gtagtcccat ctccactatt tagaaatgtt ctcagacttt aaaataatgc acagggcttg     2280

agctttctgt catttgactt taaaaggaag tttcattcat atttatcctc ttatgtaaaa     2340

ttgcggtata aagtctcatt tccaaatatg ttaaatgaca aaattatttt ataaaatgtt     2400

tatgcacact ttataacctt aagtttttat ttgagaatgt gaaagtacaa agtgcagtag     2460

acttcaacaa tcttgagtgc caagaataat acagaaaaag aagacagttg atgaatgagt     2520

ttatagggtt ctaatcttaa gatggtaaaa atgtagaaag accttgctgg ttttttgggg     2580

gtattcgttt cttaaacaat ccaaatctaa gcttagaaga aaagtttagc gttaagcacc     2640

tttatcttca tgaataagct tcagcttgct cttggcaaga gaagagtgct tgagttacag     2700

aaggcataag tagtttgaag aatgcagcag cctttttgta aacttcccag atatcaaaat     2760

agactttgat atataaatgg ttttctgaga tgacactgcc tctatttcta taaccatttc     2820

acctggacta tctaatcagt cctatgaatg tatccctaaa tgtggttatt gaaaacctaa     2880

tagctgcctc atgacaagta catgttattt aaggaggaaa aaatattaaa ttttgaattg     2940

agtgtgtagg ctccctatca ttatatatag agtttctttt tccacggtag tcagtgactt     3000

aacctgaatt gtaaatgttt gtaaagggtt aattgtccta catcaaactt agttaaataa     3060

ttccatccac ttatggagga ggaggagaat gtggaagagg taaaaagctg ggcacaagtt     3120

catatgccta tgagtcagta aagactgaag taatgtccta tgttgagctg gttattttga     3180

tatatgataa taattatctt tgaagtagaa caattctgtt aactggaaaa tcacaggata     3240

tatccatcat atttttcagg acagatagtt tttactgtgg ggcaaatagg ttaaaattac     3300

actatgttag ttgcatttag gttttaaagc aaagaatctg tagagaaatc tatgcaatat     3360

atagtttgtc cagattagct ttcatttggg gaatgaagtt ctgaaatatc taaagcagtt     3420

tactcatcaa ttgaaaagtc ctccaaaaag agaactattg ggaaaccatg gtgtggtggt     3480

ggaaaagaaa agctccctca gttttttgga gggaataact taaaaaaata cttaaatggc     3540

taagtttact tggtgcagtt aagaattaaa cttgtcaatt ttaacattgc tgttacatct     3600

gaaataaact tatgtgatgt tctggtagtg atctgtgata tctgtaaatg tcaaaactgt     3660

attgttgaat tctgcagcca gcaaccgtac atactcattg tgtagtgttt cccttactgc     3720

ttttatttac tttcacattt aagatctaat tttaaaatca ttaaaatagg ccaagtgtaa     3780

ttaaggcatc ctaattcaga tcttctgtga cttgctaggt acagtgccca atatctacaa     3840

ttcagttcca atgagaggga aaaagtaaga tccaaggaac tgtcttgctg ctgtattttt     3900

aatgtaatta ttagaaatac ttgacacttt aggctgcaat ctagttagta atgtttattg     3960

gctacagaca acatattcag gtgttttgtt tttcttcctt gtaaggaagg agtacggtag     4020

ttcaatgagt tgggaattgg cttttaagct ttttatcaaa catgaattta agattttttc     4080

tttaacagaa ttcagtattt aatatttcta gtcaaaattg ttataattag atttttgctt     4140

ttttcattta agaagcaatg agtgatcctt gtctagtgtg tctcagttat tactgtagtt     4200

taaaacaaca aacaagtatt accttccaca gttctggatc aggaatctag gagctgctta     4260

actgggtggt tctgtcttga gatctcagaa ggttgcagtc aagctgttag ccaggactgt     4320

accatcttga agcttgacaa ggctagagga gccatttcca agatgtcttg cttacgtggc     4380

tcttgggctt ctgttcctca ctgtgtgggt atcacacaca gtgcctgatg ctcacgtggc     4440

tcttgggctt cagttccttg ggcaccagtt gcctggtgga caactggtat gtggcttccc     4500

ctagagcagg tgatataaga aagtgagcag aaaccatact tttttatgac gtagcctcag     4560

gtgacattat ttctgccata ttccatgagt cacacagacc aaccattgaa tcagcttggt     4620

atagtgtggg aggggactgc acaaggatgt gaatactggg aggtggatat cattgggccc     4680

tctaggagac tggctatcac tgctcagaga agatgctggg cttcgttgac tcccaaggtc     4740

agggtagttt tggttaggtt gtgttttatt agtctctaaa aggagtagtt ttctaaatga     4800

gggttataaa gcactgcact ttacagttat tcgggatata aaagaaatag tgggtctaaa     4860

ggctgtgctc ttgtggttgg gttttcagtg gggaggggag actagtctgt ctcagactga     4920

tgctgttctc actgatttga atatttctgg gaaattggat actacagtca caaataggaa     4980

cagtaagcct atagaagttt ttcagggagt aaatattttc tatggcagtg tcctgaattg     5040

gttctccctt gcaagactga actgtaggaa cttagtccta gtttatgata cagccaagta     5100

acatagtcac atgggaaaaa gagcttgagt cagatttctt aatgtgtgtt gttaacttgg     5160

tagaacattg agaattattt aagtcagaga acgatctgtt actggggcag aaattctcaa     5220

ccttttcagt tctccaaaat ttaagatact tgatttctta ggtaaaatgt ttttgttttt     5280

gttttggaga cagagtctcg ctctgtcgcc caggctggag tgcagtggcg cgatcttggc     5340

tcactgcaaa ctccgcctcc cagattcaag caattctgcc tgagcctccc aagtagctgc     5400

gactagaaag cgcatgccac cacgcctggc taattttttg tattttagta gagatggggg     5460

tttcaccgtg ttgcccaggc tggtctcaaa ctcctgagct taggcaatcc tcctggggca     5520

gcctcccaaa gtgctaggat tacaggcgag ccatggcgcc tggccagtaa aatgttttct     5580

atctagaatg aatcaaggta ttttccttgc tcagtagctt ctagaataag aaaaaaatag     5640

cagcaagatc tgattcagaa atagttggga gcagaaagtt aatatgaagg agttgctact     5700

tgttaacagc ctagagttga gatctagaag aattattacc tttttaaatt tgtgatgaaa     5760

gcttaaatcc agcatttggg aagttactct attggctgaa ctattttgga gtttgtaagc     5820

tttgtattag atattcctga tttaactgaa actaatttgc cacatagctt taatttcatc     5880

ccagttttac ttgttttact gtcctcaaaa actcaagaca tctgaactca aaggatctaa     5940

gcagtataaa ttaaagcaca tgttgaatca ctgtagcttt cgtaggacat ctgattataa     6000

tgcttttctt tgtttctttg tccatactga acttgtctag tttatctttg agaaacattt     6060

gctagtatca aaaatcttct gtaaagattt gaacaatctt gaattctcct tgtcactagc     6120

catctcttcc cctaaagtat aataaaactg tcaggtacta aaaaaaaaaa aaa            6173


<210>  824
<211>  2707
<212>  DNA
<213>  homo sapiens

<400>  824
gggctcgagg cgttcggctg aggaagggag cgcacgccgg cggcgcggag gccggctctg       60

cgcttcgggc cgccccctcc ccccaccccg ctcacacccg gcacttactt cggctgtctc      120

cgctgccctc cagcggagac gcagctcctc aggcgcccgg cggtatttgt tgggtcggcg      180

gcgtcaggga ttcgcagtgg cctgtggtcg gcgtcgtccg gccactggtg cgcccccgcg      240

gcaggcagag ctcacgctcc tgtcccccgg ctggtccggg gtctgggcgc cgcgtcgacg      300

gcggctccgc aggacgcgca gaccgggccg cagcccattc cccgagcgga ctgcattatg      360

aggcacctgc cttacttctg ccggggtcaa gtggtgcggg gcttcggccg cggctccaag      420

cagctgggca tccccacagc taattttcct gagcaagtgg tagataatct tccagctgat      480

atatccactg gtatttacta tggttgggcc agtgttggaa gtggagatgt ccataagatg      540

gtggtgagca taggatggaa cccatattac aagaatacga agaagtctat ggaaacacat      600

atcatgcata ccttcaaaga ggacttctat ggggaaatcc tcaatgtggc cattgttggc      660

tacctgagac cagaaaagaa ctttgattct ttagagtcac ttatttcagc aattcaaggt      720

gatattgaag aagctaagaa acgactagag ttaccagaac atttgaaaat caaagaagac      780

aatttcttcc aggtttctaa aagcaaaata atgaatggcc actgatgaaa aattgtatta      840

tttattcatt cactgttttc tagtgtttct gtgtttatta ctgttcagca tcatcttggt      900

tatatactga aaatcaaaca ctttactaca gttgtgaatt agtttaaacc gtacaatgtt      960

gttatcatat catgcttcaa ctattaaatt aagcccatca tatcatagca ctaaaaagat     1020

tgagttaaaa ataagattta aaaaatatat attgattaaa atgtaccact agaaaggtat     1080

tacatgtgta taagtatggg taaaaaggca agtcactagt ttgagatgaa aactaaaatt     1140

ttcatggtaa aatgccagca tgtatgtact tgtgtagtgt gtacttctaa acagagaagg     1200

cttataaaag taaatgcatt aaggccaagt gcagtggctc acaccggtaa tcccagcact     1260

ttgggaggcc gaggtgggag gattgcttga gctcatgagt tcaagaccag cctgggcaac     1320

atagcgagac tccatctcta taaataaaaa aaaaggaaat gcattaaata gaaggttgat     1380

agtttatcat aaacctgcgg ggaagaaact cagactttct atttttgata ttttgtgcat     1440

taatacatta caaacatgaa gatgtttgta aagttttgtt ttagtcattt tctttgcagt     1500

cacatcattg taccaccttc attattgtat agagctgctt caattctgag tcctctggac     1560

ttcccctgcc tatctgtttg ttgttgttgt tgaagacagt aaaataagtg ttttcaaatc     1620

tatatgtctc ctttttgttg gataatgttt cttcttttta atggtaaata ttcttgttct     1680

tcaacatttt tctttggttc ttttttcctt ttttaggaaa aacaaaacaa cagacttcat     1740

ccttaggttt tctcaagatt taagtgaaca catttacaca tatcaatttc ttaaagaaca     1800

caaaatgttt cctccctagc aaaactattt aagagccaat taaactatga aatagttata     1860

aaattatttt taatatttaa ggccttgaaa ttatattcca aggcaaatct aaatgggtgt     1920

agttgtatat gcacgatgta atttaatgct aaagagtact tacagcttga gggaaaagca     1980

taaagtttta gttaaatagc cttcatactg tggatttttc ctcctactaa ctaatatgtg     2040

ggaaattaag attacagatg ctttgggccc cctcaaacag tacattgcta cagttcactg     2100

tagcaacaga tttggtggtg atggggggat agaggtagaa gcagatagaa ggtaatttta     2160

aagttaattt attatgaatc attttcccct aatctgcata aatgaattag aactgatttt     2220

aataaaaata ttctgtgtaa aaagtactca gaaaaacatc taaagctgtt ggagaagagg     2280

gactcatata aatagttgga ttgcgttttg ctttttattt ctttataaaa atatgtcaaa     2340

aacagttttt aattttagaa atcttatact tgaaagaaac ctcaattatc agtggcttta     2400

tgaagtaaag ttaaaaacaa acataggaaa tgtgaaaata tttgtgtttg ttttgtctga     2460

ctaacttgct gctaaatgct atctttaggt gtgtgaaagt tctttgatat gttattgtcc     2520

ttttacatct tgttaaatag ccattgcttt tgagaatcag atagtgtgtt gtttaggggt     2580

taattgtgtc tatatctttc aaaaactttt atattatgta ttataagaag ttacagtagt     2640

accattttga ttagtctgaa tgttttcagg ccttgaaata aattttgact aagtgatatt     2700

ttttctt                                                               2707


<210>  825
<211>  2548
<212>  DNA
<213>  homo sapiens

<400>  825
attccacagc ggccgcaacg tgtcgagagc cgtaagtaaa gtgtcgcaaa gcagaaggaa       60

ggcgggagtc ccgactgcaa acattgagga aagccaggca gtagaggccg ctatggcgaa      120

cgttccgtgg gcagaggtct gcgagaaatt ccaggcggcg ctcgctctgt cgcgggtgga      180

actgcataaa aatccggaga aggaaccata caagtccaaa tacagcgccc gggcgctact      240

ggaagaggtc aaggcgctgc tcggccctgc gcctgaggac gaggatgagc ggcctgaggc      300

cgaggacggc ccgggtgccg gtgaccacgc cctggggctg ccggctgagg tggtggagcc      360

cgaggggccc gtcgcccagc gagcggtgag gctggcagtc atcgagttcc acctcggggt      420

gaaccacatc gacacggagg agctgtcggc gggggaggag cacctggtga aatgcctgcg      480

gctgctgcgc aggtaccggc tctcgcacga ctgcatctct ctctgcatcc aggcgcagaa      540

taacctgggt atcttgtggt ctgaaagaga agaaattgaa actgcacagg cttacctaga      600

gtcatcagaa gcactatata atcagtatat gaaagaggtt gggagtcctc ctcttgatcc      660

tactgagcgt tttcttcctg aagaagagaa acttactgaa caagagagat caaaaagatt      720

tgaaaaggtt tatactcata acctatatta cctagctcaa gtctaccagc atctggaaat      780

gtttgagaag gctgctcact attgccatag tacactaaaa cgccagcttg agcacaatgc      840

ctaccatcct atagagtggg ctatcaatgc tgctaccttg tcacagtttt acatcaataa      900

gctatgcttt atggaggcca ggcactgttt atcagctgct aatgtcattt ttggtcaaac      960

tggaaagatc tcagccacag aagacactcc tgaagctgaa ggagaagtgc cagagcttta     1020

tcatcaaaga aagggggaaa tagcaaggtg ctggatcaaa tactgtttga ctctcatgca     1080

gaatgcccaa ctctccatgc aggacaacat aggagagctt gatcttgata aacagtctga     1140

acttagagct ttaaggaaaa aagaactaga tgaggaggaa agcattcgga aaaaagctgt     1200

gcagtttgga accggtgaac tgtgtgatgc catctctgca gtagaagaga aagtgagcta     1260

cttgagacct ttagattttg aagaagccag agaacttttc ttattgggtc agcactatgt     1320

ctttgaggca aaagagttct ttcagattga tggttatgtc actgaccata ttgaagttgt     1380

ccaagaccac agtgctctgt ttaaggtgct tgcattcttt gaaactgaca tggagagacg     1440

gtgcaagatg cataaacgca gaatagccat gctagagccc ctaactgtag acctgaatcc     1500

acagtattat ctgttggtca acagacagat ccagtttgaa attgcacatg cttactatga     1560

tatgatggat ttgaaggttg ccattgctga caggctaagg gatcctgatt cacacattgt     1620

aaaaaaaata aataatctta ataagtcagc actgaagtac taccagctct tcttagactc     1680

cctgagagac ccaaataaag tattccctga gcatataggg gaagatgttc ttcgccctgc     1740

catgttagct aagtttcgag ttgcccgtct ctatggcaaa atcattactg cagatcccaa     1800

gaaagagctg gaaaatttgg caacatcatt ggaacattac aaatttattg ttgattactg     1860

tgaaaagcat cctgaggccg cccaggaaat agaagttgag ctagaactta gtaaagagat     1920

ggttagtctt ctcccaacaa aaatggagag attcagaacc aagatggccc tgacttaatc     1980

cttgttttta aagaaaggaa atgtgcaata ttgaagtgat ctttttccct agtcagacag     2040

gcccaattcc attgtgatgt ttacctttat agccaggtga gtgcagtttg aacttgagat     2100

acagtcaact gagtgtttgc taggatccta aggaacataa agttaattaa aaacttacac     2160

ctaattatgt aaattgcctt gttaaagaca tgtgatttgt attttagatg cttgtttcct     2220

attaaaatac agacatttct accctcagtt tctaaatgta gactatttgt tggctagtac     2280

ttgatagatt ccttgtaaga aaaaatgctg ggtaatgtac ctggtaacaa gcctgttaat     2340

atattaagat tgaaaaagta acttctatag ttactccttc taaaatattt gacttcctaa     2400

attcccccca cccaaaatct ttcccttttg aaaatactaa aaactaagtt atgttattat     2460

aaagtgtaaa atggtttgtc ttaattatag gagaaaaagg ccttgttaga aataaaataa     2520

actgacttat ttcactaatg aaaacaaa                                        2548


<210>  826
<211>  3074
<212>  DNA
<213>  homo sapiens

<400>  826
ttggctacat cggacccaga tgactgcctc ctcacttcct ccctcccgat tccgccgcgg       60

cccccaaaga ctctcggggt ggccccttgt ccgcaccgct tggagggagt gtgctctgag      120

ttaagctggt ctcttctggt cctggaaaaa aatgagtatt gacaaggttg ctggatctgc      180

gcagaaaaga aagtgccact taataaaaaa tttagcccgg cagtggtacc gtctgcagag      240

cttgctgccc ttggacgtta gcaggaagcc ttcggggtgc tgtaatcggc gggcagagga      300

gagggaggcc gcggaattaa aaggaacaaa agctagagcg ccatgccaaa cgtccccggc      360

aagacccagt taggcaggag ccgggagtga tgggaaaatg aactagaata cgatgagctg      420

ccccattacg gcgggatgga cggagtaggg gttcccgctt ccatgtacgg agaccctcac      480

gcgccgcggc cgatcccccc ggttcaccac ctgaaccacg ggccgccgct ccacgccaca      540

cagcactacg gcgcgcacgc cccgcacccc aatgtcatgc cggccagtat gggatccgct      600

gtcaacgacg ccttgaagcg ggacaaggac gcgatctatg ggcacccgtt gtttcctctg      660

ttagctctgg tctttgagaa gtgcgagctg gcgacctgca ctccccggga acctggagtg      720

gctggcggag acgtctgctc ctccgactcc ttcaacgagg acatcgcggt cttcgccaag      780

caggttcgcg ccgaaaagcc acttttttcc tcaaatccag agctggacaa tttgatgata      840

caagcaatac aagtactaag gtttcatctt ttggagttag aaaaggtcca cgaactgtgc      900

gataacttct gccaccgata cattagctgt ttgaagggga aaatgcccat cgacctcgtc      960

attgatgaaa gagacggcag ctccaagtca gatcatgaag aactttcagg ctcctccaca     1020

aatctcgctg accataaccc ttcttcttgg cgagaccacg atgatgcaac ctcaacccac     1080

tcagcaggca ccccagggcc ctccagtggg ggccatgctt cccagagcgg agacaacagc     1140

agtgagcaag gggatggttt agacaacagt gtagcttcac ctggtacagg tgacgatgat     1200

gatccggata aggacaaaaa acgccagaag aaaagaggca ttttccccaa agtagcaaca     1260

aatatcatga gagcatggct cttccagcat ctcacacatc cgtacccttc cgaagagcag     1320

aagaaacagt tagcgcaaga cacaggactt acaattctcc aagtaaacaa ctggtttatt     1380

aatgccagaa gaagaatagt acagcccatg attgaccagt caaatcgagc agtgagccaa     1440

ggagcagcat atagtccaga gggtcagccc atggggagct ttgtgttgga tggtcagcaa     1500

cacatgggga tccggcctgc aggacctatg agtggaatgg gcatgaatat gggcatggat     1560

gggcaatggc actacatgta accttcatca tgtaaagcaa tcgcaaagca agggggaagt     1620

ttgcagagca tgccagggga ctacgtttct cagggtggtc ctatgggaat gagtatggca     1680

cagccaagtt acactcctcc ccagatgacc ccacacccta ctcaattaag acatggaccc     1740

ccaatgcatt catatttgcc aagccatccc caccacccag ccatgatgat gcacggagga     1800

ccccctaccc accctggaat gactatgtca gcacagagcc ccacaatgtt aaattctgta     1860

gatcccaatg ttggcggaca ggttatggac attcatgccc aatagtataa gggaactcaa     1920

gggaaaagga aacacacgca aaaactattt taagactttc tgaactttga ccagatgttg     1980

acacttaata tgaaattcca gacagctgtg attatttttt acttttgtca tttttcatca     2040

agcaacagag gaccaatgca acaagaacac aaatgtgaaa tcatgggctg actgagacaa     2100

ttctgtccat gtaaagatcc tctggaaaaa gactccgaga gttataacta ctgtagtata     2160

aatataggaa ctaagttaaa cttgtacatt tctgttgatc acgccgttat gttgcctcaa     2220

atagttttag aagagaaaaa aaaatatatc cttgttttcc acactatgtg tgttgttccc     2280

aaaagaatga ctgttttggt tcatcagtga attcaccatc caggagagac tgtggtatat     2340

attttaaacc tgttgggcca atgagaaaag aaccacactg gagatcatga tgaacttttg     2400

gctgaacctc atcactcgaa ctccagcttc aagaatgtgt tttcatgccc ggcctttgtt     2460

cctccataaa tgtgtccttt agtttcaaac agatctttat agttcgtgct tcataagcca     2520

attcttatta ttatttttgg gggactcttc ttcaaagagc ttgccaatga agatttaaag     2580

acagagcagg agcttcttcc aggagttctg agccttggtt gtggacaaaa caatcttaag     2640

ttgggcagct ttcctcaaca caaaaaaaag ttattaatgg tcattgaacc ataactagga     2700

ctttatcaga aactcaaagc ttgggggata aaaaggagca agagaatact gtaacaaact     2760

tcgtacagag ttcggtctat taattgtttc atgttagata ttctatgtgt ttacctcaat     2820

tgaaaaaaaa aagaatgttt ttgctagtat cagatctgct gtggaattgg tattgtatgt     2880

ccatgaattc ttcttttctc agcacgtgtt cctcactaga agaaaatgct gttaccttta     2940

agctttgtca aatttacatt aaaatacttg tatgaggact gtgacgttat gttaaaaaaa     3000

aaaaggtgtt aagtcacaaa aagcggtaat aaatatttca tttttgattt tttgttaaaa     3060

aaaaaaaaaa aaaa                                                       3074


<210>  827
<211>  4435
<212>  DNA
<213>  homo sapiens

<400>  827
ggcgccgacc catgctggct gggaacgtgt ctcccggtga cgcagccccg ggtggggaac       60

gtggtgcggc ggcggcggcg gcggcgactg tacgcgcctc cgccgccccc gagaggacgc      120

gccgtgcagc ggctgagtgg cggcggcggc gacggcaaac ccggagctgc cggccggcgc      180

gcgggaggag gacgcgggtg cggtctagga agtaggtccc gggctccgcg ctcaacaaag      240

acggggccgc ccccattaga cggagctgcg ggcggaggct ccatgttggg aagcggcgcc      300

gttcgtgctt gttagcggga atccgggagc cgcggggtga gctggcgggg gccgggccct      360

aagtgaagat ggaggccccg ctgcggcctg ccgcggacat cctgaggcgg aacccgcagc      420

aggactacga actcgtccag agggtcggca gcggcaccta cggggacgtc tataaggcca      480

gaaatgtaca cacaggagag ctggctgcag taaaaatcat taaattggag cctggagatg      540

atttttcttt gattcaacaa gaaatattta tggttaaaga atgtaaacat tgtaacatcg      600

ttgcctactt tgggagttat cttagtcggg aaaaactatg gatttgtatg gaatactgtg      660

gtggcggatc acttcaagat atttaccatg ttactggacc attatcagaa ttgcaaatag      720

cctatgtatg cagagaaacc ttacagggtc ttgcctattt gcatactaaa ggcaaaatgc      780

atagagatat caaaggtgct aatattttat tgacagacca tggcgatgta aaattagctg      840

actttggtgt ggctgcaaaa ataacagcta ccattgcaaa acgaaaatct ttcattggca      900

ccccttactg gatggcccca gaagttgcag cagtagagaa gaatggtggc tacaaccaac      960

tctgtgatat ctgggcagta ggaataacag caattgaact tggagaactt cagccaccta     1020

tgtttgatct ccacccaatg agggctctct tcttaatgtc aaaaagtaat tttcagcctc     1080

caaaactaaa ggacaaaaca aaatggtcat caacattcca taattttgtc aaaatagcac     1140

taaccaaaaa cccaaaaaaa agaccaactg ctgaaagact tctgactcac acttttgttg     1200

cacagccagg tctctctaga gccctagcag ttgaactgtt agacaaagtg aacaatccag     1260

ataaccacgc acattacact gaagcagatg acgatgactt tgagccccat gcaatcattc     1320

gtcataccat tagatctaca aacaggaatg ccagagctga acggacagct tcagaaataa     1380

attttgacaa attacaattt gaacctcctc tgagaaaaga aacagaagca cgagatgaaa     1440

tgggattgtc atcagaccca aatttcatgt tacagtggaa tccttttgtt gatggtgcaa     1500

atactggcaa atcaacctca aaacgtgcaa taccacctcc cctacctcct aagccaagga     1560

taagcagtta ccctgaagac aactttccgg atgaagaaaa agcatcaacc ataaaacatt     1620

gtcctgattc agaaagcaga gctccccaaa ttctcagaag acagagtagc ccaagttgtg     1680

ggcctgtggc agagacttct tctattggaa atggtgatgg tatttcaaaa ctgatgagtg     1740

aaaatacaga aggatcagca caagcaccac agttaccacg aaaaaaggac aaacgagact     1800

tccctaaacc agccatcaat ggccttccac ccaccccaaa agttctgatg ggagcatgct     1860

tttcaaaagt ttttgatggc tgtcctttga aaattaattg tgcaacatcc tggatacatc     1920

ctgatacaaa agatcagtac attatttttg gaactgaaga tggtatttac acactgaatc     1980

tcaatgagct acatgaggca acgatggaac agttatttcc acggaagtgt acttggctgt     2040

atgttatcaa taatacttta atgtcattat cagaaggaaa aacctttcag ctctactctc     2100

acaatcttat agctttgttt gaacatgcca aaaaaccagg attagctgcc catattcaaa     2160

ctcacaggtt tccagaccga atactaccaa gaaaattcgc tttaacaaca aagattcctg     2220

atacaaaagg ctgccacaaa tgttgcatag tcagaaaccc ttacacggga cataaatacc     2280

tctgtggagc tttacagtct ggaattgttt tacttcagtg gtatgagcca atgcagaaat     2340

tcatgttgat aaagcacttt gattttcctt tgccaagtcc tttgaatgtt tttgaaatgc     2400

tggtgatacc tgaacaggaa taccctatgg tctgtgtagc tattagcaaa ggcactgaat     2460

cgaatcaggt agttcagttt gagacaatca atttgaactc tgcatcttca tggtttacag     2520

aaattggtgc aggcagccag cagttagatt ccattcatgt aacacagttg gagagagata     2580

ccgttttagt gtgtttagac aaatttgtga aaattgtaaa tctacaagga aaattaaaat     2640

caagtaagaa actggcctct gagttaagtt ttgattttcg cattgaatct gtagtatgcc     2700

ttcaagacag tgtgttggct ttctggaaac atgggatgca gggtaaaagc ttcaagtcag     2760

atgaggttac ccaggagatt tcagatgaaa caagagtttt ccgcttatta ggatcagaca     2820

gggttgtcgt tttggaaagt aggccaacag aaaatcctac tgcacacagc aatctctaca     2880

tcttggctgg acatgaaaat agttactaag caacagaaac tgatctcaaa tgacaggaaa     2940

atgaatatac tccattgaaa ggaaaaataa ggaaattcaa tacaaactgc actatgattt     3000

gctttaacta ttatgggtta tattgcaaat gatctgtact ttagggtaga attcaatatt     3060

ttctgcagct ggaaacagct agtctatctc ttgccactgt gtggtggtta tatcaagttt     3120

gcttaataaa agctatgaga caaatagtcc tctagttcca ggaaacacag tcttttttta     3180

aaaaaaacaa tgtttgtaac aagggtgcca tggtattttt agataactcg tgattatctt     3240

aagagaggta aatttagtga tcattttata tcatgtctta ttccttctta atgaacataa     3300

tttgttaaat tctcaagcaa ggttttcact tttatattgg ccattctgta tgtttttgta     3360

aaacagaata tttaatcctt atttattaat ctcttgctgg agtggtgtaa tgtatctaac     3420

ttttagcaaa ggagggttgc agagcagctt aaattttttt tataatgtat aagaattttg     3480

tttatctttt aagagtagta aagtactttg agtgtttggg ggttcaacac acacatgcaa     3540

ttttgcttaa caaaagtatt ttataataca gtttcataca gaattacctt aaaagggagt     3600

cttatgtttt caactacaga tagttgtaag ggatcataca gaagatattg atgatagttg     3660

aaatattctt agaaggggtg tgtatgtcta gctgtgtcta ccatgtgtat gtattcttga     3720

caagcagtat aaaatacctg tgatttttct ttacattagg gataatgcat aaggaattaa     3780

tcttcatata tattatcatc cctaatgtag cagggggaag tatttaattg cccatgatat     3840

gtattttact tatactatgc cagagaggaa actataaagt aattacacat gtaatcttgg     3900

gtttttcaca tatgtaggta ttcattttga gtaggttgaa gaagaaaaaa aatatttaaa     3960

tgaattgaat tcctgatggg atagtatcaa taagtattta aaagccagta ttctaaaaat     4020

aataaagggt agggtcattt ttgagtttgt ttttcttttg ctattgttaa tattcaaaat     4080

taaagtgtta cattggtacc tgttgtctta atgcatttat tgagaacagc attgagatga     4140

tgaacaaggg gttagcaata gcaaactcta taattatttt gactaattac ttaagaggaa     4200

aacagtataa gtatctcatt cagtatttag caattctgta aaataagtat tatctctatt     4260

tttcagatga ggaagtaagg gtttagcaag gttaagagat ctatccaatt tacacagcaa     4320

gttagtagtt gagcctgacc atgagtcttc tgactctgtt cttttcacta tgcaatacgc     4380

aaacaataaa atgttataca aatggaatat aaagttattt attctttaaa aatgc          4435


<210>  828
<211>  4387
<212>  DNA
<213>  homo sapiens

<400>  828
ggcgccgacc catgctggct gggaacgtgt ctcccggtga cgcagccccg ggtggggaac       60

gtggtgcggc ggcggcggcg gcggcgactg tacgcgcctc cgccgccccc gagaggacgc      120

gccgtgcagc ggctgagtgg cggcggcggc gacggcaaac ccggagctgc cggccggcgc      180

gcgggaggag gacgcgggtg cggtctagga aacggagctg cgggcggagg ctccatgttg      240

ggaagcggcg ccgttcgtgc ttgttagcgg gaatccggga gccgcggggt gagctggcgg      300

gggccgggcc ctaagtgaag atggaggccc cgctgcggcc tgccgcggac atcctgaggc      360

ggaacccgca gcaggactac gaactcgtcc agagggtcgg cagcggcacc tacggggacg      420

tctataaggc cagaaatgta cacacaggag agctggctgc agtaaaaatc attaaattgg      480

agcctggaga tgatttttct ttgattcaac aagaaatatt tatggttaaa gaatgtaaac      540

attgtaacat cgttgcctac tttgggagtt atcttagtcg ggaaaaacta tggatttgta      600

tggaatactg tggtggcgga tcacttcaag atatttacca tgttactgga ccattatcag      660

aattgcaaat agcctatgta tgcagagaaa ccttacaggg tcttgcctat ttgcatacta      720

aaggcaaaat gcatagagat atcaaaggtg ctaatatttt attgacagac catggcgatg      780

taaaattagc tgactttggt gtggctgcaa aaataacagc taccattgca aaacgaaaat      840

ctttcattgg caccccttac tggatggccc cagaagttgc agcagtagag aagaatggtg      900

gctacaacca actctgtgat atctgggcag taggaataac agcaattgaa cttggagaac      960

ttcagccacc tatgtttgat ctccacccaa tgagggctct cttcttaatg tcaaaaagta     1020

attttcagcc tccaaaacta aaggacaaaa caaaatggtc atcaacattc cataattttg     1080

tcaaaatagc actaaccaaa aacccaaaaa aaagaccaac tgctgaaaga cttctgactc     1140

acacttttgt tgcacagcca ggtctctcta gagccctagc agttgaactg ttagacaaag     1200

tgaacaatcc agataaccac gcacattaca ctgaagcaga tgacgatgac tttgagcccc     1260

atgcaatcat tcgtcatacc attagatcta caaacaggaa tgccagagct gaacggacag     1320

cttcagaaat aaattttgac aaattacaat ttgaacctcc tctgagaaaa gaaacagaag     1380

cacgagatga aatgggattg tcatcagacc caaatttcat gttacagtgg aatccttttg     1440

ttgatggtgc aaatactggc aaatcaacct caaaacgtgc aataccacct cccctacctc     1500

ctaagccaag gataagcagt taccctgaag acaactttcc ggatgaagaa aaagcatcaa     1560

ccataaaaca ttgtcctgat tcagaaagca gagctcccca aattctcaga agacagagta     1620

gcccaagttg tgggcctgtg gcagagactt cttctattgg aaatggtgat ggtatttcaa     1680

aactgatgag tgaaaataca gaaggatcag cacaagcacc acagttacca cgaaaaaagg     1740

acaaacgaga cttccctaaa ccagccatca atggccttcc acccacccca aaagttctga     1800

tgggagcatg cttttcaaaa gtttttgatg gctgtccttt gaaaattaat tgtgcaacat     1860

cctggataca tcctgataca aaagatcagt acattatttt tggaactgaa gatggtattt     1920

acacactgaa tctcaatgag ctacatgagg caacgatgga acagttattt ccacggaagt     1980

gtacttggct gtatgttatc aataatactt taatgtcatt atcagaagga aaaacctttc     2040

agctctactc tcacaatctt atagctttgt ttgaacatgc caaaaaacca ggattagctg     2100

cccatattca aactcacagg tttccagacc gaatactacc aagaaaattc gctttaacaa     2160

caaagattcc tgatacaaaa ggctgccaca aatgttgcat agtcagaaac ccttacacgg     2220

gacataaata cctctgtgga gctttacagt ctggaattgt tttacttcag tggtatgagc     2280

caatgcagaa attcatgttg ataaagcact ttgattttcc tttgccaagt cctttgaatg     2340

tttttgaaat gctggtgata cctgaacagg aataccctat ggtctgtgta gctattagca     2400

aaggcactga atcgaatcag gtagttcagt ttgagacaat caatttgaac tctgcatctt     2460

catggtttac agaaattggt gcaggcagcc agcagttaga ttccattcat gtaacacagt     2520

tggagagaga taccgtttta gtgtgtttag acaaatttgt gaaaattgta aatctacaag     2580

gaaaattaaa atcaagtaag aaactggcct ctgagttaag ttttgatttt cgcattgaat     2640

ctgtagtatg ccttcaagac agtgtgttgg ctttctggaa acatgggatg cagggtaaaa     2700

gcttcaagtc agatgaggtt acccaggaga tttcagatga aacaagagtt ttccgcttat     2760

taggatcaga cagggttgtc gttttggaaa gtaggccaac agaaaatcct actgcacaca     2820

gcaatctcta catcttggct ggacatgaaa atagttacta agcaacagaa actgatctca     2880

aatgacagga aaatgaatat actccattga aaggaaaaat aaggaaattc aatacaaact     2940

gcactatgat ttgctttaac tattatgggt tatattgcaa atgatctgta ctttagggta     3000

gaattcaata ttttctgcag ctggaaacag ctagtctatc tcttgccact gtgtggtggt     3060

tatatcaagt ttgcttaata aaagctatga gacaaatagt cctctagttc caggaaacac     3120

agtctttttt taaaaaaaac aatgtttgta acaagggtgc catggtattt ttagataact     3180

cgtgattatc ttaagagagg taaatttagt gatcatttta tatcatgtct tattccttct     3240

taatgaacat aatttgttaa attctcaagc aaggttttca cttttatatt ggccattctg     3300

tatgtttttg taaaacagaa tatttaatcc ttatttatta atctcttgct ggagtggtgt     3360

aatgtatcta acttttagca aaggagggtt gcagagcagc ttaaattttt tttataatgt     3420

ataagaattt tgtttatctt ttaagagtag taaagtactt tgagtgtttg ggggttcaac     3480

acacacatgc aattttgctt aacaaaagta ttttataata cagtttcata cagaattacc     3540

ttaaaaggga gtcttatgtt ttcaactaca gatagttgta agggatcata cagaagatat     3600

tgatgatagt tgaaatattc ttagaagggg tgtgtatgtc tagctgtgtc taccatgtgt     3660

atgtattctt gacaagcagt ataaaatacc tgtgattttt ctttacatta gggataatgc     3720

ataaggaatt aatcttcata tatattatca tccctaatgt agcaggggga agtatttaat     3780

tgcccatgat atgtatttta cttatactat gccagagagg aaactataaa gtaattacac     3840

atgtaatctt gggtttttca catatgtagg tattcatttt gagtaggttg aagaagaaaa     3900

aaaatattta aatgaattga attcctgatg ggatagtatc aataagtatt taaaagccag     3960

tattctaaaa ataataaagg gtagggtcat ttttgagttt gtttttcttt tgctattgtt     4020

aatattcaaa attaaagtgt tacattggta cctgttgtct taatgcattt attgagaaca     4080

gcattgagat gatgaacaag gggttagcaa tagcaaactc tataattatt ttgactaatt     4140

acttaagagg aaaacagtat aagtatctca ttcagtattt agcaattctg taaaataagt     4200

attatctcta tttttcagat gaggaagtaa gggtttagca aggttaagag atctatccaa     4260

tttacacagc aagttagtag ttgagcctga ccatgagtct tctgactctg ttcttttcac     4320

tatgcaatac gcaaacaata aaatgttata caaatggaat ataaagttat ttattcttta     4380

aaaatgc                                                               4387


<210>  829
<211>  6657
<212>  DNA
<213>  homo sapiens

<400>  829
ctccgctccg actgcttgta ggcgatgccc aggcaaagac cgtgactgac actctcgctc       60

acacgcacgc acggacccag gcccacgctc ggagatcgag ccccgggctc gcaaccgttg      120

tcgctcccgg cgccgcggcc agagcccgga ccacggcttc cgcgccgccg ccgcctcgcc      180

gagaagggcc gcgccggacc tcgagcgcgg cggcccccgg ccggcaggga tggggaagcg      240

ggcgggagga ggagcaaccg gagccaccac cgccgccgtc tccacgtccg ccggggccgg      300

gctggaacct gcggccgccc gtagcggggg cccgcggagc gcggccgccg gcctcctagg      360

cgcgctgcac ctggtgatga ccctcgtagt ggctgcggcg cgggccgaga aggaagcatt      420

cgttcagtca gagagcataa tagaagtact gcgttttgat gatggagggc tactacagac      480

cgagacaaca cttggactca gttcatatca gcagaaaagt atatctctct accgggggaa      540

ttgcaggccc atacgatttg agccaccaat gctggatttc catgaacaac cagttggaat      600

gccaaaaatg gaaaaagtct acttacataa tcctagttct gaagaaacga ttactttagt      660

atcaatatct gctacaacat cacattttca tgcatcattt tttcaaaata ggaaaattct      720

tccaggagga aatacatcat ttgatgtagt ttttcttgca agagtagtag gaaatgtaga      780

aaatacttta tttattaata catctaatca tggggtattt acttaccagg tatttggtgt      840

tggagttcca aatccatatc gattgaggcc gttccttggg gccagagtcc ctgtgaatag      900

cagtttctca cctataataa acatccacaa tcctcacagt gagcctttac aggttgtaga      960

aatgtactct agtggaggag accttcacct agaactccca acgggtcaac aaggaggtac     1020

cagaaaactg tgggaaattc ctccttatga aaccaaggga gtgatgagag ccagtttttc     1080

atctagagaa gcagataatc acacagcctt cataagaata aagactaatg cttcagacag     1140

cacagagttt atcattcttc ctgttgaggt tgaagttaca acagctcctg gaatttattc     1200

ctcaactgaa atgttagatt ttggtacact aagaacacaa gatctaccaa aagttttaaa     1260

ccttcattta ttaaattcag gaacaaaaga tgtaccaata acaagtgttc gacctacacc     1320

acaaaatgat gctataacgg tacactttaa accaattaca ttaaaagcat cagaaagtaa     1380

atacaccaag gttgcaagca ttagttttga tgcatcgaag gcaaaaaagc catctcagtt     1440

ttctgggaaa ataacagtta aagcaaagga aaagagttat tctaaacttg aaataccata     1500

tcaagcagaa gttttagatg gttatttggg atttgatcat gctgcaacat tatttcacat     1560

ccgagacagc cctgctgatc ctgtggaaag gccaatttac cttactaaca ctttcagttt     1620

tgcgatcctc attcacgatg tgttgctacc agaagaagcc aaaacaatgt ttaaagttca     1680

caacttcagc aaaccagtct taattcttcc taatgaatca ggatacattt ttaccctgct     1740

ttttatgcct tccacatcat ccatgcacat tgataacaac attttactta ttaccaatgc     1800

ttctaaattt catttacccg tgcgggtata cacaggcttt ttagattact ttgtattgcc     1860

ccccaaaata gaggaacgtt tcatagattt tggagtactg agtgctacag aagcaagtaa     1920

tattttattt gcaattataa acagcaatcc aattgagttg gctataaaaa gttggcatat     1980

cataggagac ggtttatcaa tagaacttgt agctgtggaa agaggcaata gaactacaat     2040

aatttcaagc ctgccagagt ttgaaaaatc ctctttatca gatcaatcat cggtaacatt     2100

agcttcaggc tattttgcag tcttcagagt caaacttact gcaaaaaaat tagaggggat     2160

tcatgatgga gccatccaga tcacaacaga ctatgagatc ctgacaatcc ctgtgaaggc     2220

tgtgattgca gtaggctcac tgacctgctt ccctaagcac gtggttcttc caccttcctt     2280

tccagggaaa atagttcatc aaagtttaaa tattatgaat tccttctcac agaaggtaaa     2340

aatacagcaa atacgatctt tgtcagaaga tgtgcgattt tactataaac gattacgggg     2400

caataaggaa gacttggagc caggaaaaaa atcaaagatt gcaaacattt attttgatcc     2460

tggactacag tgtggggatc attgctatgt tggcttgcct tttctatcca aatctgaacc     2520

caaagtgcag cctggtgtag ccatgcagga agatatgtgg gatgctgact gggatttgca     2580

tcaaagcctg ttcaagggat ggacaggaat aaaggaaaat tcaggtcata gattgagtgc     2640

tatatttgaa gtaaatacag accttcaaaa aaatataata tcaaaaatca ctgctgagct     2700

ctcctggcct tccatactta gctcaccccg gcacttgaaa tttccactta ctaatacaaa     2760

ctgctcctca gaagaagaga ttactttaga aaatcctgca gatgttcctg tctatgttca     2820

gtttattcct ctggctttat attccaaccc ttcagtgttt gtagataagt tagtatcaag     2880

gtttaacttg agtaaggtgg caaagataga tttgagaaca ctagaatttc aagtcttcag     2940

aaacagtgct catccactgc agagttcaac aggatttatg gagggcctct ctcgacattt     3000

aattttaaac ctaattttaa aacctggaga aaagaaatct gtcaaagtaa agtttactcc     3060

agttcacaac agaactgttt cttcacttat catagtcaga aataacctga ctgtgatgga     3120

tgctgtgatg gtccaaggac aaggaacaac tgagaacttg agggtggcag gcaagcttcc     3180

aggtccagga agctccttac gctttaaaat cacggaagca ttgttaaaag attgtacaga     3240

tagtttaaaa ctaagagaac caaatttcac attgaaaaga acatttaagg tagagaatac     3300

aggacaactt caaattcaca tagaaaccat tgaaatcagt ggatactcat gtgaaggata     3360

tggctttaaa gttgttaatt gtcaagagtt tactctaagt gccaatgctt ctagagatat     3420

aatcatattg tttactcctg attttacagc ttctagagtt attcgggaac tgaagtttat     3480

aacaaccagt ggctctgagt ttgtatttat attgaatgca tcccttcctt accatatgtt     3540

agcaacctgt gcagaagccc tacccagacc taactgggaa ctggctctgt atatcatcat     3600

ctcaggaata atgagtgcac tgtttctttt ggtcattgga acagcctatt tggaagctca     3660

aggaatatgg gagccatttc gaaggcggct atcctttgag gcctcgaacc cgcccttcga     3720

tgtgggaagg ccatttgatc tcaggagaat cgttggtatt tcatctgaag gaaacttgaa     3780

cacactcagc tgtgaccccg gtcacagtag ggggttctgt ggagcaggcg gttcatcatc     3840

ccgacccagt gccgggagtc ataagcagtg tggcccatcg gtccacccac acagcagtca     3900

cagcaataga aactcagctg acgtggaaaa cgtcagagcc aaaaacagtt caagtacctc     3960

tagtaggact tctgctcaag cagcttcttc acagtctgct aacaaaacaa gcccccttgt     4020

cttagattcg aacacagtga ctcaaggtca tacagcgggc agaaagtcca aaggggcaaa     4080

gcagagccag cacggcagcc agcaccatgc ccacagcccg ctggagcagc accctcagcc     4140

tcctctgcca ccgccagtgc ctcagcccca ggagccgcag cctgaaaggc tgtctcccgc     4200

ccccctcgca cacccttccc acccagaacg tgccagcagc gcgaggcaca gttccgagga     4260

ctcggacatc accagtctca tagaagccat ggacaaagac ttcgaccacc atgactcccc     4320

agccctagaa gtgtttacag agcagcctcc atcgccattg ccaaaaagca aagggaaagg     4380

aaaacctctt cagcgcaagg tgaaaccacc taagaagcaa gaggaaaagg agaagaaggg     4440

aaagggaaag ccacaggaag atgagctgaa ggactctttg gctgatgatg atagctcctc     4500

caccaccaca gagacctcca accctgacac agaaccgctc ctcaaggagg atacagaaaa     4560

gcaaaaggga aaacaagcca tgcctgaaaa acatgaaagt gaaatgtctc aagtgaagca     4620

aaaaagcaaa aaactcttaa atattaagaa agaaatccca acagatgtga aacccagttc     4680

attagaacta ccatatactc cccctttgga aagtaagcaa cgtagaaatc tcccaagcaa     4740

gattcctctt ccaactgcaa tgacaagtgg atccaaatca cgaaatgccc agaaaacaaa     4800

aggtacaagt aagttagtgg ataacagacc acctgcccta gcaaaattcc tcccgaatag     4860

tcaagaatta ggcaacacca gtagctcaga gggtgaaaaa gactctcctc caccggagtg     4920

ggattccgtt ccagttcaca aacctggcag ctctactgat agtctttata aactttctct     4980

gcaaaccctc aacgcagaca ttttcttaaa acaacgccag acctcaccga cacctgcttc     5040

cccgtctccc ccagctgccc cctgcccctt tgtggcccgg ggcagctaca gcagcatcgt     5100

caacagcagc tccagcagtg accctaaaat aaaacagcca aatggaagca aacacaagtt     5160

gacaaaggca gcctcgctcc cgggcaagaa cggcaacccc acttttgctg cagtcacggc     5220

tggctacgac aagagcccag gtgggaatgg ctttgctaaa gtttcttcaa acaaaacagg     5280

tttctccagc agccttggca tttcacacgc tcctgttgac agcgatggct cagacagctc     5340

gggtttgtgg agtcccgtca gcaacccaag cagccctgac ttcactcccc tcaattcgtt     5400

ctccgccttt ggaaactctt ttaatctaac tggtgaagtt ttcagcaaac tcggattatc     5460

tcgatcgtgc aatcaggcct cacagaggag ctggaacgag tttaatagtg gcccttcata     5520

cctttgggag tcgccagcga cagatcccag tccttcctgg ccagccagtt ccggctcccc     5580

gacccacaca gccacatcgg tcctcggtaa caccagcggc ctgtggtcca ccactccatt     5640

cagcagctcc atttggtcca gcaaccttag cagcgccctt cccttcacca ctccagcaaa     5700

cacgctggca agcatcggcc tcatgggcac agaaaactcc cctgctcctc acgctccctc     5760

cacctccagt ccagctgacg acttgggaca gacctacaac ccgtggcgga tatggagccc     5820

cacgattgga agaagaagct cggacccttg gtctaattcg cactttcctc acgagaatta     5880

aattaagcaa aaaacaaaca aacatagtgg gccctcgtct agatcatgat gtgccagttt     5940

ctgagacatc tttttaaggc tcttactgca gctcccctcc ccaccctcct cttctttgca     6000

aaacagaccc aagcagggca ggctcagacc actcgcttct ttcagatctt tcttgcaatt     6060

atgataacat gagatttgct gttgtgcttt tagagaaaag tctggactca gccacaaact     6120

ctaataagac ctgtacatct gagaaccttt cccgttactg cgttttcacc acctgtcttc     6180

cccatgcttt atttatctgt atgaacacag atttgacatt acagctaagg aaataatttg     6240

agttgattca gaaatcctgg catgtgacaa ttttgttaaa ttaccaagtt tggtttttaa     6300

taatttctca atattatgcg ccaagatcta attttaaaac tgtatgagga ctttgtgctg     6360

aaaatagagt atttttttaa agtaaggctg tcttggttta aaagcagatt acagaaatgt     6420

aagtcaactt aagaacggtg aatgaatgta aaaacattca gttgagacca tatgcatttt     6480

ctgtgctgtt tgtacttgag gtatgtaaca tttgtatacc tgaacttatt ttaaagatga     6540

actgaaatgc acatagccaa gtcttgagat acaagattga atgtgtattt cttaaaaata     6600

caactttgtg ttgtactttg aaataaatga tgcttttttc aaaaaaaaaa aaaaaaa        6657


<210>  830
<211>  6657
<212>  DNA
<213>  homo sapiens

<400>  830
ctccgctccg actgcttgta ggcgatgccc aggcaaagac cgtgactgac actctcgctc       60

acacgcacgc acggacccag gcccacgctc ggagatcgag ccccgggctc gcaaccgttg      120

tcgctcccgg cgccgcggcc agagcccgga ccacggcttc cgcgccgccg ccgcctcgcc      180

gagaagggcc gcgccggacc tcgagcgcgg cggcccccgg ccggcaggga tggggaagcg      240

ggcgggagga ggagcaaccg gagccaccac cgccgccgtc tccacgtccg ccggggccgg      300

gctggaacct gcggccgccc gtagcggggg cccgcggagc gcggccgccg gcctcctagg      360

cgcgctgcac ctggtgatga ccctcgtagt ggctgcggcg cgggccgaga aggaagcatt      420

cgttcagtca gagagcataa tagaagtact gcgttttgat gatggagggc tactacagac      480

cgagacaaca cttggactca gttcatatca gcagaaaagt atatctctct accgggggaa      540

ttgcaggccc atacgatttg agccaccaat gctggatttc catgaacaac cagttggaat      600

gccaaaaatg gaaaaagtct acttacataa tcctagttct gaagaaacga ttactttagt      660

atcaatatct gctacaacat cacattttca tgcatcattt tttcaaaata ggaaaattct      720

tccaggagga aatacatcat ttgatgtagt ttttcttgca agagtagtag gaaatgtaga      780

aaatacttta tttattaata catctaatca tggggtattt acttaccagg tatttggtgt      840

tggagttcca aatccatatc gattgaggcc gttccttggg gccagagtcc ctgtgaatag      900

cagtttctca cctataataa acatccacaa tcctcacagt gagcctttac aggttgtaga      960

aatgtactct agtggaggag accttcacct agaactccca acgggtcaac aaggaggtac     1020

cagaaaactg tgggaaattc ctccttatga aaccaaggga gtgatgagag ccagtttttc     1080

atctagagaa gcagataatc acacagcctt cataagaata aagactaatg cttcagacag     1140

cacagagttt atcattcttc ctgttgaggt tgaagttaca acagctcctg gaatttattc     1200

ctcaactgaa atgttagatt ttggtacact aagaacacaa gatctaccaa aagttttaaa     1260

ccttcattta ttaaattcag gaacaaaaga tgtaccaata acaagtgttc gacctacacc     1320

acaaaatgat gctataacgg tacactttaa accaattaca ttaaaagcat cagaaagtaa     1380

atacaccaag gttgcaagca ttagttttga tgcatcgaag gcaaaaaagc catctcagtt     1440

ttctgggaaa ataacagtta aagcaaagga aaagagttat tctaaacttg aaataccata     1500

tcaagcagaa gttttagatg gttatttggg atttgatcat gctgcaacat tatttcacat     1560

ccgagacagc cctgctgatc ctgtggaaag gccaatttac cttactaaca ctttcagttt     1620

tgcgatcctc attcacgatg tgttgctacc agaagaagcc aaaacaatgt ttaaagttca     1680

caacttcagc aaaccagtct taattcttcc taatgaatca ggatacattt ttaccctgct     1740

ttttatgcct tccacatcat ccatgcacat tgataacaac attttactta ttaccaatgc     1800

ttctaaattt catttacccg tgcgggtata cacaggcttt ttagattact ttgtattgcc     1860

ccccaaaata gaggaacgtt tcatagattt tggagtactg agtgctacag aagcaagtaa     1920

tattttattt gcaattataa acagcaatcc aattgagttg gctataaaaa gttggcatat     1980

cataggagac ggtttatcaa tagaacttgt agctgtggaa agaggcaata gaactacaat     2040

aatttcaagc ctgccagagt ttgaaaaatc ctctttatca gatcaatcat cggtaacatt     2100

agcttcaggc tattttgcag tcttcagagt caaacttact gcaaaaaaat tagaggggat     2160

tcatgatgga gccatccaga tcacaacaga ctatgagatc ctgacaatcc ctgtgaaggc     2220

tgtgattgca gtaggctcac tgacctgctt ccctaagcac gtggttcttc caccttcctt     2280

tccagggaaa atagttcatc aaagtttaaa tattatgaat tccttctcac agaaggtaaa     2340

aatacagcaa atacgatctt tgtcagaaga tgtgcgattt tactataaac gattacgggg     2400

caataaggaa gacttggagc caggaaaaaa atcaaagatt gcaaacattt attttgatcc     2460

tggactacag tgtggggatc attgctatgt tggcttgcct tttctatcca aatctgaacc     2520

caaagtgcag cctggtgtag ccatgcagga agatatgtgg gatgctgact gggatttgca     2580

tcaaagcctg ttcaagggat ggacaggaat aaaggaaaat tcaggtcata gattgagtgc     2640

tatatttgaa gtaaatacag accttcaaaa aaatataata tcaaaaatca ctgctgagct     2700

ctcctggcct tccatactta gctcaccccg gcacttgaaa tttccactta ctaatacaaa     2760

ctgctcctca gaagaagaga ttactttaga aaatcctgca gatgttcctg tctatgttca     2820

gtttattcct ctggctttat attccaaccc ttcagtgttt gtagataagt tagtatcaag     2880

gtttaacttg agtaaggtgg caaagataga tttgagaaca ctagaatttc aagtcttcag     2940

aaacagtgct catccactgc agagttcaac aggatttatg gagggcctct ctcgacattt     3000

aattttaaac ctaattttaa aacctggaga aaagaaatct gtcaaagtaa agtttactcc     3060

agttcacaac agaactgttt cttcacttat catagtcaga aataacctga ctgtgatgga     3120

tgctgtgatg gtccaaggac aaggaacaac tgagaacttg agggtggcag gcaagcttcc     3180

aggtccagga agctccttac gctttaaaat cacggaagca ttgttaaaag attgtacaga     3240

tagtttaaaa ctaagagaac caaatttcac attgaaaaga acatttaagg tagagaatac     3300

aggacaactt caaattcaca tagaaaccat tgaaatcagt ggatactcat gtgaaggata     3360

tggctttaaa gttgttaatt gtcaagagtt tactctaagt gccaatgctt ctagagatat     3420

aatcatattg tttactcctg attttacagc ttctagagtt attcgggaac tgaagtttat     3480

aacaaccagt ggctctgagt ttgtatttat attgaatgca tcccttcctt accatatgtt     3540

agcaacctgt gcagaagccc tacccagacc taactgggaa ctggctctgt atatcatcat     3600

ctcaggaata atgagtgcac tgtttctttt ggtcattgga acagcctatt tggaagctca     3660

aggaatatgg gagccatttc gaaggcggct atcctttgag gcctcgaacc cgcccttcga     3720

tgtgggaagg ccatttgatc tcaggagaat cgttggtatt tcatctgaag gaaacttgaa     3780

cacactcagc tgtgaccccg gtcacagtag ggggttctgt ggagcaggcg gttcatcatc     3840

ccgacccagt gccgggagtc ataagcagtg tggcccatcg gtccacccac acagcagtca     3900

cagcaataga aactcagctg acgtggaaaa cgtcagagcc aaaaacagtt caagtacctc     3960

tagtaggact tctgctcaag cagcttcttc acagtctgct aacaaaacaa gcccccttgt     4020

cttagattcg aacacagtga ctcaaggtca tacagcgggc agaaagtcca aaggggcaaa     4080

gcagagccag cacggcagcc agcaccatgc ccacagcccg ctggagcagc accctcagcc     4140

tcctctgcca ccgccagtgc ctcagcccca ggagccgcag cctgaaaggc tgtctcccgc     4200

ccccctcgca cacccttccc acccagaacg tgccagcagc gcgaggcaca gttccgagga     4260

ctcggacatc accagtctca tagaagccat ggacaaagac ttcgaccacc atgactcccc     4320

agccctagaa gtgtttacag agcagcctcc atcgccattg ccaaaaagca aagggaaagg     4380

aaaacctctt cagcgcaagg tgaaaccacc taagaagcaa gaggaaaagg agaagaaggg     4440

aaagggaaag ccacaggaag atgagctgaa ggactctttg gctgatgatg atagctcctc     4500

caccaccaca gagacctcca accctgacac agaaccgctc ctcaaggagg atacagaaaa     4560

gcaaaaggga aaacaagcca tgcctgaaaa acatgaaagt gaaatgtctc aagtgaagca     4620

aaaaagcaaa aaactcttaa atattaagaa agaaatccca acagatgtga aacccagttc     4680

attagaacta ccatatactc cccctttgga aagtaagcaa cgtagaaatc tcccaagcaa     4740

gattcctctt ccaactgcaa tgacaagtgg atccaaatca cgaaatgccc agaaaacaaa     4800

aggtacaagt aagttagtgg ataacagacc acctgcccta gcaaaattcc tcccgaatag     4860

tcaagaatta ggcaacacca gtagctcaga gggtgaaaaa gactctcctc caccggagtg     4920

ggattccgtt ccagttcaca aacctggcag ctctactgat agtctttata aactttctct     4980

gcaaaccctc aacgcagaca ttttcttaaa acaacgccag acctcaccga cacctgcttc     5040

cccgtctccc ccagctgccc cctgcccctt tgtggcccgg ggcagctaca gcagcatcgt     5100

caacagcagc tccagcagtg accctaaaat aaaacagcca aatggaagca aacacaagtt     5160

gacaaaggca gcctcgctcc cgggcaagaa cggcaacccc acttttgctg cagtcacggc     5220

tggctacgac aagagcccag gtgggaatgg ctttgctaaa gtttcttcaa acaaaacagg     5280

tttctccagc agccttggca tttcacacgc tcctgttgac agcgatggct cagacagctc     5340

gggtttgtgg agtcccgtca gcaacccaag cagccctgac ttcactcccc tcaattcgtt     5400

ctccgccttt ggaaactctt ttaatctaac tggtgaagtt ttcagcaaac tcggattatc     5460

tcgatcgtgc aatcaggcct cacagaggag ctggaacgag tttaatagtg gcccttcata     5520

cctttgggag tcgccagcga cagatcccag tccttcctgg ccagccagtt ccggctcccc     5580

gacccacaca gccacatcgg tcctcggtaa caccagcggc ctgtggtcca ccactccatt     5640

cagcagctcc atttggtcca gcaaccttag cagcgccctt cccttcacca ctccagcaaa     5700

cacgctggca agcatcggcc tcatgggcac agaaaactcc cctgctcctc acgctccctc     5760

cacctccagt ccagctgacg acttgggaca gacctacaac ccgtggcgga tatggagccc     5820

cacgattgga agaagaagct cggacccttg gtctaattcg cactttcctc acgagaatta     5880

aattaagcaa aaaacaaaca aacatagtgg gccctcgtct agatcatgat gtgccagttt     5940

ctgagacatc tttttaaggc tcttactgca gctcccctcc ccaccctcct cttctttgca     6000

aaacagaccc aagcagggca ggctcagacc actcgcttct ttcagatctt tcttgcaatt     6060

atgataacat gagatttgct gttgtgcttt tagagaaaag tctggactca gccacaaact     6120

ctaataagac ctgtacatct gagaaccttt cccgttactg cgttttcacc acctgtcttc     6180

cccatgcttt atttatctgt atgaacacag atttgacatt acagctaagg aaataatttg     6240

agttgattca gaaatcctgg catgtgacaa ttttgttaaa ttaccaagtt tggtttttaa     6300

taatttctca atattatgcg ccaagatcta attttaaaac tgtatgagga ctttgtgctg     6360

aaaatagagt atttttttaa agtaaggctg tcttggttta aaagcagatt acagaaatgt     6420

aagtcaactt aagaacggtg aatgaatgta aaaacattca gttgagacca tatgcatttt     6480

ctgtgctgtt tgtacttgag gtatgtaaca tttgtatacc tgaacttatt ttaaagatga     6540

actgaaatgc acatagccaa gtcttgagat acaagattga atgtgtattt cttaaaaata     6600

caactttgtg ttgtactttg aaataaatga tgcttttttc aaaaaaaaaa aaaaaaa        6657


<210>  831
<211>  3642
<212>  DNA
<213>  homo sapiens

<400>  831
gacggtgctg tccaggggga ggcgggcgga gggaaggcgc tgccgctgct gccgccgcct       60

cgcccgaagc gacacagacg ctgggagcgg ccgaggcgag tgatttcttc tgacttgagc      120

ctgcagtgtg ctgtgagaga tctaccacta gattatctca actttggtct cctgggacca      180

ctcgttgctg acagtcagaa aaagaaaaag aactctgaaa tgaaattgag gatttgaact      240

tcacacagct gtttgaactg aattcttgcc gccaggatgg ggaaacagaa cagcaagctg      300

cgcccggagg tcatgcagga cttgctggaa agcacagact ttacagagca tgagatccag      360

gaatggtata aaggcttctt gagagactgc cccagtggac atttgtcaat ggaagagttt      420

aagaaaatat atgggaactt tttcccttat ggggatgctt ccaaatttgc agagcatgtc      480

ttccgcacct tcgatgcaaa tggagatggg acaatagact ttagagaatt catcatcgcc      540

ttgagtgtaa cttcgagggg gaagctggag cagaagctga aatgggcctt cagcatgtac      600

gacctggacg gaaatggcta tatcagcaag gcagagatgc tagagatcgt gcaggcaatc      660

tataagatgg tttcctctgt aatgaaaatg cctgaagatg agtcaacccc agagaaaaga      720

acagaaaaga tcttccgcca gatggacacc aatagagacg gaaaactctc cctggaagag      780

ttcatccgag gagccaaaag cgacccgtcc attgtgcgcc tcctgcagtg cgacccgagc      840

agtgccggcc agttctgagc cctgcgccca ccaatcgaat tgtagagctg cttgtgttcc      900

cttttgattc ttctttttaa caattttttt ttttttttgc caaacaatat caatggtgat      960

gccgtcccct gtgcggtctg atgcgccttc ctccgtgacg ccttcagctt cttttgtcgt     1020

ggatgcttcg tgggaatgcc cagagcccca gtgtgcttgt ggagagcatg gacagacttc     1080

gtggtgttca ttgtttgatg atttttaatc gttactatta ttttttttta ttctaatgtc     1140

tctgttctaa aacgtaagac tcgggggttg gggcaaaaga agggaaaccc atccagtcct     1200

gtgattctat tgcaagcttc aaggggcttt tgtttgaaag acaaaactcc ccacctgaat     1260

ctgttgtcac acgtgccgta ggggtgatgg atggcaccgg atgctggatt ccccaagaac     1320

aagttaccct ctggggtgag gctattccag cgagctggga catttcccca tgggggccca     1380

ctcccctctc ttccccagca ggctgtagtt tctaagctgt gaacatttca agataaatta     1440

acagaggaga ggaaaaagat ggctcagcta ttttttcaca ggtttacact agttgagcta     1500

atatgcgtgt ctttggaaat taaacacaaa tggtaacata ttccaaaacc agacccatct     1560

tgttgcctat tgtgataaaa taaaaagacg gctgtatata acatattggg taatgcagac     1620

caaattaagt gttttgcctt gtttaaatga aatgcatgtt tagtgagcac taatacaatc     1680

ttattccaga agactgtttt tagtagctta ttgtgaagta agacaactat aatgaatgtc     1740

tgtcttgttt ggaagtcata tctgtctttg cacaaatgta ccaatcgaca agtatatttt     1800

atatattcca taaaaataca aagtaaccct gactagggcc caactttaat tttgaatgca     1860

tttccagagt ggccatgcct agagggcaga tgcagagcag gtggtagtgg gacaggacaa     1920

ttggagcaca ggaatgttaa catgtatgac aggggaccag tagggtggtt tccctctcag     1980

gcccagcagc ccattgacag cattagactg gcggcatggt gcttttctga gcagatcaat     2040

actctgcaga ctcgaaaaaa catcacatac attcttggaa cttcccagtg gtttaatcta     2100

tgtgcatggt tagggagcca ggtctggaat attcagtttc cctgcccctg ttaaagaatc     2160

agaggttggg cagtcatcaa attcatcata aagacatggg caagtgtgtc tgtggtttcc     2220

aaggcccccc tatggagaat ccaaaagtat tttccattgc cgtgctcttt gaatgcagac     2280

ttctatttcc agaagtgaca gcacaagtct gagttgctgt ttggtctggt gacctcagac     2340

acactaattt gaattgaaag ctaagagtaa aaatttgctg gttacaggcg agtcatactc     2400

ttgcaagtag ttagcaaagg gaggcccaaa ttctcaaggt tgttgatggg gaacttgcca     2460

ctaagagaag gcagagaggt ccctagtggg tatatttgct gccaagccac ttgccaaaga     2520

agaggaacca cagaaagaga gacatcatga ccaggagaaa aatgtgacta gacatgctaa     2580

cctccaggtt tttatatatg acttgagtct gctgtaattg gcagcagaaa tccaaatttg     2640

tatggtagac caaaaagaac caaatccata gggtgaaatt ttgagaccta gactctgtaa     2700

aaataatcct agtcttcctc caggggtcag ttcctcacag tggttctgta ccaaaacttg     2760

ccaaattcct ccatggccaa gtgttaaaat ctgtgtttgg aaaatagcga attaacctaa     2820

gacacagaag gcagactggg tgaggagacc tagcatgccc tattggcagt gctcaggagc     2880

tgcatcccac ttttccctgc tctgaatcga agtcctagtt ccttcctttg attctccttt     2940

ggtaggtgga atcagttaat gttttgagaa acctgcctgg gctctgccct tagtcatgac     3000

atctcgctga gccagaccca ctctgttcct tggaacctag agctggagtg aggagtagag     3060

gtctccggct attccagaaa gaaaagtgag ccacatgcag gctgatgaat gccgacactt     3120

ccagaatgta tagaaatagt ccctgtcctg gcctgccact gaccctgtct gtattttctc     3180

ggaggttgtt tttctccttc tccttcccag gaaggtcttt gtatgtcgaa tccagtgcac     3240

tcaagtttgg ccaagggact ccacagcacc cagaagactg catgcctcaa ggtttatgtc     3300

actcctctgc tgggctgttc attgtcattg ctgtgttcag ggacctttgg aaataaaacc     3360

tgttctgtcc caaataaaac cagcctgtga tgttcaaggg actggaataa agtggcttac     3420

gacctgaagg attctacaga gtgctcaact gttcatacat cattcagagt gggagggagc     3480

tgggggtgct gtcccatccc atctgtatgc ccacggtgga tttaataata tataatttat     3540

aaatcatagc ctatggagtg gcccgtaaat cagttgactg tgtagctctt gcctggcatt     3600

aaagcatgtt tttggtttaa catgaaaaaa aaaaaaaaaa aa                        3642


<210>  832
<211>  3826
<212>  DNA
<213>  homo sapiens

<400>  832
aggggcccct tagatgtctt cctccggatt ttttgttaag cttttcctag acagtttaca       60

gaaggctttg ggtagagaaa gcactagtta gacaaaagca gcccccctcc caccttgtgg      120

gcatgaagag tccagaggac accacctgag aagcttttca actgccttcc aaggctccct      180

tgaacttcac tgcggtagag cagggacccc agaccccccc tcaaatcgaa gcttggaagg      240

aggtgctcta ggctgaatct gacctcccag gacccgagga ggcaagcaga tggcacccct      300

tggaaagtag cagtgcaggc tggctagagg cctgggcgag tgatttcttc tgacttgagc      360

ctgcagtgtg ctgtgagaga tctaccacta gattatctca actttggtct cctgggacca      420

ctcgttgctg acagtcagaa actgaattct tgccgccagg atggggaaac agaacagcaa      480

gctgcgcccg gaggtcatgc aggacttgct ggaaagcaca gactttacag agcatgagat      540

ccaggaatgg tataaaggct tcttgagaga ctgccccagt ggacatttgt caatggaaga      600

gtttaagaaa atatatggga actttttccc ttatggggat gcttccaaat ttgcagagca      660

tgtcttccgc accttcgatg caaatggaga tgggacaata gactttagag aattcatcat      720

cgccttgagt gtaacttcga gggggaagct ggagcagaag ctgaaatggg ccttcagcat      780

gtacgacctg gacggaaatg gctatatcag caaggcagag atgctagaga tcgtgcaggc      840

aatctataag atggtttcct ctgtaatgaa aatgcctgaa gatgagtcaa ccccagagaa      900

aagaacagaa aagatcttcc gccagatgga caccaataga gacggaaaac tctccctgga      960

agagttcatc cgaggagcca aaagcgaccc gtccattgtg cgcctcctgc agtgcgaccc     1020

gagcagtgcc ggccagttct gagccctgcg cccaccaatc gaattgtaga gctgcttgtg     1080

ttcccttttg attcttcttt ttaacaattt tttttttttt ttgccaaaca atatcaatgg     1140

tgatgccgtc ccctgtgcgg tctgatgcgc cttcctccgt gacgccttca gcttcttttg     1200

tcgtggatgc ttcgtgggaa tgcccagagc cccagtgtgc ttgtggagag catggacaga     1260

cttcgtggtg ttcattgttt gatgattttt aatcgttact attatttttt tttattctaa     1320

tgtctctgtt ctaaaacgta agactcgggg gttggggcaa aagaagggaa acccatccag     1380

tcctgtgatt ctattgcaag cttcaagggg cttttgtttg aaagacaaaa ctccccacct     1440

gaatctgttg tcacacgtgc cgtaggggtg atggatggca ccggatgctg gattccccaa     1500

gaacaagtta ccctctgggg tgaggctatt ccagcgagct gggacatttc cccatggggg     1560

cccactcccc tctcttcccc agcaggctgt agtttctaag ctgtgaacat ttcaagataa     1620

attaacagag gagaggaaaa agatggctca gctatttttt cacaggttta cactagttga     1680

gctaatatgc gtgtctttgg aaattaaaca caaatggtaa catattccaa aaccagaccc     1740

atcttgttgc ctattgtgat aaaataaaaa gacggctgta tataacatat tgggtaatgc     1800

agaccaaatt aagtgttttg ccttgtttaa atgaaatgca tgtttagtga gcactaatac     1860

aatcttattc cagaagactg tttttagtag cttattgtga agtaagacaa ctataatgaa     1920

tgtctgtctt gtttggaagt catatctgtc tttgcacaaa tgtaccaatc gacaagtata     1980

ttttatatat tccataaaaa tacaaagtaa ccctgactag ggcccaactt taattttgaa     2040

tgcatttcca gagtggccat gcctagaggg cagatgcaga gcaggtggta gtgggacagg     2100

acaattggag cacaggaatg ttaacatgta tgacagggga ccagtagggt ggtttccctc     2160

tcaggcccag cagcccattg acagcattag actggcggca tggtgctttt ctgagcagat     2220

caatactctg cagactcgaa aaaacatcac atacattctt ggaacttccc agtggtttaa     2280

tctatgtgca tggttaggga gccaggtctg gaatattcag tttccctgcc cctgttaaag     2340

aatcagaggt tgggcagtca tcaaattcat cataaagaca tgggcaagtg tgtctgtggt     2400

ttccaaggcc cccctatgga gaatccaaaa gtattttcca ttgccgtgct ctttgaatgc     2460

agacttctat ttccagaagt gacagcacaa gtctgagttg ctgtttggtc tggtgacctc     2520

agacacacta atttgaattg aaagctaaga gtaaaaattt gctggttaca ggcgagtcat     2580

actcttgcaa gtagttagca aagggaggcc caaattctca aggttgttga tggggaactt     2640

gccactaaga gaaggcagag aggtccctag tgggtatatt tgctgccaag ccacttgcca     2700

aagaagagga accacagaaa gagagacatc atgaccagga gaaaaatgtg actagacatg     2760

ctaacctcca ggtttttata tatgacttga gtctgctgta attggcagca gaaatccaaa     2820

tttgtatggt agaccaaaaa gaaccaaatc catagggtga aattttgaga cctagactct     2880

gtaaaaataa tcctagtctt cctccagggg tcagttcctc acagtggttc tgtaccaaaa     2940

cttgccaaat tcctccatgg ccaagtgtta aaatctgtgt ttggaaaata gcgaattaac     3000

ctaagacaca gaaggcagac tgggtgagga gacctagcat gccctattgg cagtgctcag     3060

gagctgcatc ccacttttcc ctgctctgaa tcgaagtcct agttccttcc tttgattctc     3120

ctttggtagg tggaatcagt taatgttttg agaaacctgc ctgggctctg cccttagtca     3180

tgacatctcg ctgagccaga cccactctgt tccttggaac ctagagctgg agtgaggagt     3240

agaggtctcc ggctattcca gaaagaaaag tgagccacat gcaggctgat gaatgccgac     3300

acttccagaa tgtatagaaa tagtccctgt cctggcctgc cactgaccct gtctgtattt     3360

tctcggaggt tgtttttctc cttctccttc ccaggaaggt ctttgtatgt cgaatccagt     3420

gcactcaagt ttggccaagg gactccacag cacccagaag actgcatgcc tcaaggttta     3480

tgtcactcct ctgctgggct gttcattgtc attgctgtgt tcagggacct ttggaaataa     3540

aacctgttct gtcccaaata aaaccagcct gtgatgttca agggactgga ataaagtggc     3600

ttacgacctg aaggattcta cagagtgctc aactgttcat acatcattca gagtgggagg     3660

gagctggggg tgctgtccca tcccatctgt atgcccacgg tggatttaat aatatataat     3720

ttataaatca tagcctatgg agtggcccgt aaatcagttg actgtgtagc tcttgcctgg     3780

cattaaagca tgtttttggt ttaacatgaa aaaaaaaaaa aaaaaa                    3826


<210>  833
<211>  3735
<212>  DNA
<213>  homo sapiens

<400>  833
agtcacaact tcgggggttg aggttgtcaa ggagctgtcc gtgatggttc tatggtgtgt       60

gcgtacacac atactctctc tctcacacac acacaccaca gtgacagatg acctattgaa      120

ataatttcag agccggtctg tggttgctac gacaaccaat gatctcttgg ctttcatctg      180

gccatgtgac agggactttg acgtcagcta gaggcagagt ctgtggctga gtccacacag      240

tcaaaggctt gtgagaatct ggtggatgct ggaccttgct gctgctgcta ctgctgtttc      300

caggggctgc agagcatgga ctgttaaatc ttgcacttct tctgagtgag ctgaattctt      360

gccgccagga tggggaaaca gaacagcaag ctgcgcccgg aggtcatgca ggacttgctg      420

gaaagcacag actttacaga gcatgagatc caggaatggt ataaaggctt cttgagagac      480

tgccccagtg gacatttgtc aatggaagag tttaagaaaa tatatgggaa ctttttccct      540

tatggggatg cttccaaatt tgcagagcat gtcttccgca ccttcgatgc aaatggagat      600

gggacaatag actttagaga attcatcatc gccttgagtg taacttcgag ggggaagctg      660

gagcagaagc tgaaatgggc cttcagcatg tacgacctgg acggaaatgg ctatatcagc      720

aaggcagaga tgctagagat cgtgcaggca atctataaga tggtttcctc tgtaatgaaa      780

atgcctgaag atgagtcaac cccagagaaa agaacagaaa agatcttccg ccagatggac      840

accaatagag acggaaaact ctccctggaa gagttcatcc gaggagccaa aagcgacccg      900

tccattgtgc gcctcctgca gtgcgacccg agcagtgccg gccagttctg agccctgcgc      960

ccaccaatcg aattgtagag ctgcttgtgt tcccttttga ttcttctttt taacaatttt     1020

tttttttttt tgccaaacaa tatcaatggt gatgccgtcc cctgtgcggt ctgatgcgcc     1080

ttcctccgtg acgccttcag cttcttttgt cgtggatgct tcgtgggaat gcccagagcc     1140

ccagtgtgct tgtggagagc atggacagac ttcgtggtgt tcattgtttg atgattttta     1200

atcgttacta ttattttttt ttattctaat gtctctgttc taaaacgtaa gactcggggg     1260

ttggggcaaa agaagggaaa cccatccagt cctgtgattc tattgcaagc ttcaaggggc     1320

ttttgtttga aagacaaaac tccccacctg aatctgttgt cacacgtgcc gtaggggtga     1380

tggatggcac cggatgctgg attccccaag aacaagttac cctctggggt gaggctattc     1440

cagcgagctg ggacatttcc ccatgggggc ccactcccct ctcttcccca gcaggctgta     1500

gtttctaagc tgtgaacatt tcaagataaa ttaacagagg agaggaaaaa gatggctcag     1560

ctattttttc acaggtttac actagttgag ctaatatgcg tgtctttgga aattaaacac     1620

aaatggtaac atattccaaa accagaccca tcttgttgcc tattgtgata aaataaaaag     1680

acggctgtat ataacatatt gggtaatgca gaccaaatta agtgttttgc cttgtttaaa     1740

tgaaatgcat gtttagtgag cactaataca atcttattcc agaagactgt ttttagtagc     1800

ttattgtgaa gtaagacaac tataatgaat gtctgtcttg tttggaagtc atatctgtct     1860

ttgcacaaat gtaccaatcg acaagtatat tttatatatt ccataaaaat acaaagtaac     1920

cctgactagg gcccaacttt aattttgaat gcatttccag agtggccatg cctagagggc     1980

agatgcagag caggtggtag tgggacagga caattggagc acaggaatgt taacatgtat     2040

gacaggggac cagtagggtg gtttccctct caggcccagc agcccattga cagcattaga     2100

ctggcggcat ggtgcttttc tgagcagatc aatactctgc agactcgaaa aaacatcaca     2160

tacattcttg gaacttccca gtggtttaat ctatgtgcat ggttagggag ccaggtctgg     2220

aatattcagt ttccctgccc ctgttaaaga atcagaggtt gggcagtcat caaattcatc     2280

ataaagacat gggcaagtgt gtctgtggtt tccaaggccc ccctatggag aatccaaaag     2340

tattttccat tgccgtgctc tttgaatgca gacttctatt tccagaagtg acagcacaag     2400

tctgagttgc tgtttggtct ggtgacctca gacacactaa tttgaattga aagctaagag     2460

taaaaatttg ctggttacag gcgagtcata ctcttgcaag tagttagcaa agggaggccc     2520

aaattctcaa ggttgttgat ggggaacttg ccactaagag aaggcagaga ggtccctagt     2580

gggtatattt gctgccaagc cacttgccaa agaagaggaa ccacagaaag agagacatca     2640

tgaccaggag aaaaatgtga ctagacatgc taacctccag gtttttatat atgacttgag     2700

tctgctgtaa ttggcagcag aaatccaaat ttgtatggta gaccaaaaag aaccaaatcc     2760

atagggtgaa attttgagac ctagactctg taaaaataat cctagtcttc ctccaggggt     2820

cagttcctca cagtggttct gtaccaaaac ttgccaaatt cctccatggc caagtgttaa     2880

aatctgtgtt tggaaaatag cgaattaacc taagacacag aaggcagact gggtgaggag     2940

acctagcatg ccctattggc agtgctcagg agctgcatcc cacttttccc tgctctgaat     3000

cgaagtccta gttccttcct ttgattctcc tttggtaggt ggaatcagtt aatgttttga     3060

gaaacctgcc tgggctctgc ccttagtcat gacatctcgc tgagccagac ccactctgtt     3120

ccttggaacc tagagctgga gtgaggagta gaggtctccg gctattccag aaagaaaagt     3180

gagccacatg caggctgatg aatgccgaca cttccagaat gtatagaaat agtccctgtc     3240

ctggcctgcc actgaccctg tctgtatttt ctcggaggtt gtttttctcc ttctccttcc     3300

caggaaggtc tttgtatgtc gaatccagtg cactcaagtt tggccaaggg actccacagc     3360

acccagaaga ctgcatgcct caaggtttat gtcactcctc tgctgggctg ttcattgtca     3420

ttgctgtgtt cagggacctt tggaaataaa acctgttctg tcccaaataa aaccagcctg     3480

tgatgttcaa gggactggaa taaagtggct tacgacctga aggattctac agagtgctca     3540

actgttcata catcattcag agtgggaggg agctgggggt gctgtcccat cccatctgta     3600

tgcccacggt ggatttaata atatataatt tataaatcat agcctatgga gtggcccgta     3660

aatcagttga ctgtgtagct cttgcctggc attaaagcat gtttttggtt taacatgaaa     3720

aaaaaaaaaa aaaaa                                                      3735


<210>  834
<211>  1921
<212>  DNA
<213>  homo sapiens

<400>  834
ctgcctcccc cccgctcccg ctcccctgag cccagccaga ccccgcgccg cccgcgcccc       60

gctcgactcc ggaggctccc gcagccccgg cgtccgcccc gctgccccct cccccggggg      120

ccatgggggc gcccccgggc taccggccct cagcttgggt gcatctcctc caccagctgc      180

cccgcgccga cttccagctc cgcccggtgc ccagcgtttt cgcgccccaa gagcaggaat      240

accagcaggc cttgttgctg gtggcggcct tggcgggcct gggcttgggc ctgagcctca      300

ttttcatcgc tgtctacctc atccgcttct gctgctgccg gccccccgag ccccccgggt      360

ccaagatccc ctcgcccggg ggaggctgcg tcacctggag ctgcattgtc gcccttctcg      420

ccggctgcac tggcattggc atcggtttct atggcaacag tgagaccagt gatggggtgt      480

cccagctcag ctctgcgctg ctgcacgcca accacacact cagcaccatt gaccacctgg      540

tgttggagac ggtggagagg ctgggcgagg cggtgaggac agagctgacc accctggagg      600

aggtgctcga gccgcgcacg gagctggtgg ctgccgcccg aggggctcga cggcaggcgg      660

aggctgcggc ccagcagctg caggggctgg ccttctggca gggagtgccc ctgagccccc      720

tgcaggtggc tgaaaatgtg tcctttgtgg aggagtacag gtggctggcc tacgtcctcc      780

tgctgctcct ggagctgctg gtctgcctct tcaccctcct gggcctggcg aagcagagca      840

agtggctggt gatcgtgatg acagtcatga gtctcctggt tctcgtcctg agctggggct      900

ccatgggcct ggaggcagcc acggccgtgg gcctcagtga cttctgctcc aatccagacc      960

cttatgttct gaacctgacc caggaggaga cagggctcag ctcagacatc ctgagctatt     1020

atctcctctg caaccgggcc gtctccaacc ccttccaaca gaggctgact ctgtcccagc     1080

gagctctggc caacatccac tcccagctgc tgggcctgga gcgagaagct gtgcctcagt     1140

tcccttcagc gcagaagcct ctgctgtcct tggaggagac tctgaatgtg acagaaggaa     1200

atttccacca gttggtggca ctgctacact gccgcagcct gcacaaggac tatggtgcag     1260

ccctgcgggg cctgtgcgaa gacgccctgg aaggcctgct cttcctgcta ctcttctccc     1320

tgctgtctgc aggagcgctg gccactgccc tctgcagcct gccccgagcc tgggccctct     1380

tcccacccag tgacgactac gatgacacag acgatgacga ccctttcaac cctcaggaat     1440

ccaagcgctt tgtgcagtgg cagtcgtcta tctgagcccc tcctcccggc tggactggag     1500

cctggctccc ctcttcgttc cttccctggc tgccggagga gaccccacta acccagcctg     1560

cctgggctct gaccactaac actcttggcc atggacagcc tgcacaggac cgcctccctg     1620

ctcttggcca ctgtgctccc atttctgtcc ttggccttgg gagtagctga gggggcagac     1680

tagggagtag ggctggcagg ggagggggca gacagcctcg cctcgcaccc ttcatccctg     1740

gctgccggtc ccatccttgg agggactaag ctgggggtgg gggacatgag tccccctgct     1800

gcccctgcca catcccagtg ggctctgacc ccctgatctc aactcgtggc actaacttgg     1860

aaaagggttg atttaaaata aaagggaaga ctattttaca agcaaaaaaa aaaaaaaaaa     1920

a                                                                     1921


<210>  835
<211>  3662
<212>  DNA
<213>  homo sapiens

<400>  835
gcgagctggt ggttgaagct ggttaaagaa cagcctaggt attccagaag tgtttgagga       60

tcccttccat gaaggaagag aggaaagttt ttaagtaaac ctcccactcc catgtgtctt      120

cagctttctt ttgcaaagga gaaaatcctt gaagtttggt aaagaccgag ttagtctatc      180

tctctttgcc tatctcgagt tgggctgggg agaggaggag ataggttctt ttgtcttttt      240

ctgtcttctc ccttccccac ttccttccct ccagtcccca ctcactcaca tgcacacact      300

aaccttggag ccgatgggat tgagtgactg gcacttggga ccacagagaa atgtcagagt      360

gtttggttac agactcaagg aaacctctca ttttagagtg ctcatttggt tttgagcaaa      420

attttggact gtgaagcaag gcattggtga agacaaaatg gcctcgccgg ctgacagctg      480

tatccagttc acccgccatg ccagtgatgt tcttctcaac cttaatcgtc tccggagtcg      540

agacatcttg actgatgttg tcattgttgt gagccgtgag cagtttagag cccataaaac      600

ggtcctcatg gcctgcagtg gcctgttcta tagcatcttt acagaccagt tgaaatgcaa      660

ccttagtgtg atcaatctag atcctgagat caaccctgag ggattctgca tcctcctgga      720

cttcatgtac acatctcggc tcaatttgcg ggagggcaac atcatggctg tgatggccac      780

ggctatgtac ctgcagatgg agcatgttgt ggacacttgc cggaagttta ttaaggccag      840

tgaagcagag atggtttctg ccatcaagcc tcctcgtgaa gagttcctca acagccggat      900

gctgatgccc caagacatca tggcctatcg gggtcgtgag gtggtggaga acaacctgcc      960

actgaggagc gcccctgggt gtgagagcag agcctttgcc cccagcctgt acagtggcct     1020

gtccacaccg ccagcctctt attccatgta cagccacctc cctgtcagca gcctcctctt     1080

ctccgatgag gagtttcggg atgtccggat gcctgtggcc aaccccttcc ccaaggagcg     1140

ggcactccca tgtgatagtg ccaggccagt ccctggtgag tacagccggc cgactttgga     1200

ggtgtccccc aatgtgtgcc acagcaatat ctattcaccc aaggaaacaa tcccagaaga     1260

ggcacgaagt gatatgcact acagtgtggc tgagggcctc aaacctgctg ccccctcagc     1320

ccgaaatgcc ccctacttcc cttgtgacaa ggccagcaaa gaagaagaga gaccctcctc     1380

ggaagatgag attgccctgc atttcgagcc ccccaatgca cccctgaacc ggaagggtct     1440

ggttagtcca cagagccccc agaaatctga ctgccagccc aactcgccca cagagtcctg     1500

cagcagtaag aatgcctgca tcctccaggc ttctggctcc cctccagcca agagccccac     1560

tgaccccaaa gcctgcaact ggaagaaata caagttcatc gtgctcaaca gcctcaacca     1620

gaatgccaaa ccagaggggc ctgagcaggc tgagctgggc cgcctttccc cacgagccta     1680

cacggcccca cctgcctgcc agccacccat ggagcctgag aaccttgacc tccagtcccc     1740

aaccaagctg agtgccagcg gggaggactc caccatccca caagccagcc ggctcaataa     1800

catcgttaac aggtccatga cgggctctcc ccgcagcagc agcgagagcc actcaccact     1860

ctacatgcac cccccgaagt gcacgtcctg cggctctcag tccccacagc atgcagagat     1920

gtgcctccac accgctggcc ccacgttccc tgaggagatg ggagagaccc agtctgagta     1980

ctcagattct agctgtgaga acggggcctt cttctgcaat gagtgtgact gccgcttctc     2040

tgaggaggcc tcactcaaga ggcacacgct gcagacccac agtgacaaac cctacaagtg     2100

tgaccgctgc caggcctcct tccgctacaa gggcaacctc gccagccaca agaccgtcca     2160

taccggtgag aaaccctatc gttgcaacat ctgtggggcc cagttcaacc ggccagccaa     2220

cctgaaaacc cacactcgaa ttcactctgg agagaagccc tacaaatgcg aaacctgcgg     2280

agccagattt gtacaggtgg cccacctccg tgcccatgtg cttatccaca ctggtgagaa     2340

gccctatccc tgtgaaatct gtggcacccg tttccggcac cttcagactc tgaagagcca     2400

cctgcgaatc cacacaggag agaaacctta ccattgtgag aagtgtaacc tgcatttccg     2460

tcacaaaagc cagctgcgac ttcacttgcg ccagaagcat ggcgccatca ccaacaccaa     2520

ggtgcaatac cgcgtgtcag ccactgacct gcctccggag ctccccaaag cctgctgaag     2580

catggagtgt tgatgctttc gtctccagcc ccttctcaga atctacccaa aggatactgt     2640

aacactttac aatgttcatc ccatgatgta gtgcctcttt catccactag tgcaaatcat     2700

agctgggggt tgggggtggt gggggtcggg gcctggggga ctgggagccg cagcagctcc     2760

ccctccccca ctgccataaa acattaagaa aatcatattg cttcttctcc tatgtgtaag     2820

gtgaaccatg tcagcaaaaa gcaaaatcat tttatatgtc aaagcagggg agtatgcaaa     2880

agttctgact tgactttagt ctgcaaaatg aggaatgtat atgttttgtg ggaacagatg     2940

tttcttttgt atgtaaatgt gcattctttt aaaagacaag acttcagtat gttgtcaaag     3000

agagggcttt aattttttta accaaaggtg aaggaatata tggcagagtt gtaaatatat     3060

aaatatatat atatataaaa taaatatata taaacctaaa aaagatatat taaaaatata     3120

aaactgcgtt aaaggctcga ttttgtatct gcaggcagac acggatctga gaatctttat     3180

tgagaaagag cacttaagag aatattttaa gtattgcatc tgtataagta agaaaatatt     3240

ttgtctaaaa tgcctcagtg tatttgtatt tttttgcaag tgaaggttta caatttacaa     3300

agtgtgtatt aaaaaaaaca aaaagaacaa aaaaatctgc agaaggaaaa atgtgtaatt     3360

ttgttctagt tttcagtttg tatatacccg tacaacgtgt cctcacggtg ccttttttca     3420

cggaagtttt caatgatggg cgagcgtgca ccatcccttt ttgaagtgta ggcagacaca     3480

gggacttgaa gttgttacta actaaactct ctttgggaat gtttgtctca tcccattctg     3540

cgtcatgctt gtgttataac tactccggag acagggtttg gctgtgtcta aactgcatta     3600

ccgcgttgta aaatatagct gtacaaatat aagaataaaa tgttgaaaag tcaaactgga     3660

aa                                                                    3662


<210>  836
<211>  3631
<212>  DNA
<213>  homo sapiens

<400>  836
gcggccgctg cagagattgg aatccgcctg ccgggcttgg cgaaggagaa gggaggaggc       60

aggagcgagg agggaggagg gccaagggcg ggcaggaagg cttaggctcg gcgcgtccgt      120

ccgcgcgcgg cgaagatcgc acggcccgat cgaggggcga ccgggtcggg gccgctgcac      180

gccaagggcg aaggccgatt cgggccccac ttcgccccgg cggctcgccg cgcccacccg      240

ctccgcgccg agggctggag gatgcgttcc ctggggtccg gacttatgaa aatatgcatc      300

agtttaatac tgtcttggaa ttcatgagat ggaagcatag gtcaaagctg tttggagaaa      360

atcagaagta cagttttatc tagccacatc ttggaggagt cgtaagaaag cagtgggagt      420

tgaagtcatt gtcaagtgct tgcgatcttt tacaagaaaa tctcactgaa tgatagtcat      480

ttaaattggt gaagtagcaa gaccaattat taaaggtgac agtacacagg aaacattaca      540

attgaacaat gcctcagcta tacatttaca tcagattatt gggagcctat ttgttcatca      600

tttctcgtgt tcaaggacag aatctggata gtatgcttca tggcactggg atgaaatcag      660

actccgacca gaaaaagtca gaaaatggag taaccttagc accagaggat accttgcctt      720

ttttaaagtg ctattgctca gggcactgtc cagatgatgc tattaataac acatgcataa      780

ctaatggaca ttgctttgcc atcatagaag aagatgacca gggagaaacc acattagctt      840

cagggtgtat gaaatatgaa ggatctgatt ttcagtgcaa agattctcca aaagcccagc      900

tacgccggac aatagaatgt tgtcggacca atttatgtaa ccagtatttg caacccacac      960

tgccccctgt tgtcataggt ccgttttttg atggcagcat tcgatggctg gttttgctca     1020

tttctatggc tgtctgcata attgctatga tcatcttctc cagctgcttt tgttacaaac     1080

attattgcaa gagcatctca agcagacgtc gttacaatcg tgatttggaa caggatgaag     1140

catttattcc agttggagaa tcactaaaag accttattga ccagtcacaa agttctggta     1200

gtgggtctgg actaccttta ttggttcagc gaactattgc caaacagatt cagatggtcc     1260

ggcaagttgg taaaggccga tatggagaag tatggatggg caaatggcgt ggcgaaaaag     1320

tggcggtgaa agtattcttt accactgaag aagccagctg gtttcgagaa acagaaatct     1380

accaaactgt gctaatgcgc catgaaaaca tacttggttt catagcggca gacattaaag     1440

gtacaggttc ctggactcag ctctatttga ttactgatta ccatgaaaat ggatctctct     1500

atgacttcct gaaatgtgct acactggaca ccagagccct gcttaaattg gcttattcag     1560

ctgcctgtgg tctgtgccac ctgcacacag aaatttatgg cacccaagga aagcccgcaa     1620

ttgctcatcg agacctaaag agcaaaaaca tcctcatcaa gaaaaatggg agttgctgca     1680

ttgctgacct gggccttgct gttaaattca acagtgacac aaatgaagtt gatgtgccct     1740

tgaataccag ggtgggcacc aaacgctaca tggctcccga agtgctggac gaaagcctga     1800

acaaaaacca cttccagccc tacatcatgg ctgacatcta cagcttcggc ctaatcattt     1860

gggagatggc tcgtcgttgt atcacaggag ggatcgtgga agaataccaa ttgccatatt     1920

acaacatggt accgagtgat ccgtcatacg aagatatgcg tgaggttgtg tgtgtcaaac     1980

gtttgcggcc aattgtgtct aatcggtgga acagtgatga atgtctacga gcagttttga     2040

agctaatgtc agaatgctgg gcccacaatc cagcctccag actcacagca ttgagaatta     2100

agaagacgct tgccaagatg gttgaatccc aagatgtaaa aatctgatgg ttaaaccatc     2160

ggaggagaaa ctctagactg caagaactgt ttttacccat ggcatgggtg gaattagagt     2220

ggaataagga tgttaacttg gttctcagac tctttcttca ctacgtgttc acaggctgct     2280

aatattaaac ctttcagtac tcttattagg atacaagctg ggaacttcta aacacttcat     2340

tctttatata tggacagctt tattttaaat gtggtttttg atgccttttt ttaagtgggt     2400

ttttatgaac tgcatcaaga cttcaatcct gattagtgtc tccagtcaag ctctgggtac     2460

tgaattgcct gttcataaaa cggtgctttc tgtgaaagcc ttaagaagat aaatgagcgc     2520

agcagagatg gagaaataga ctttgccttt tacctgagac attcagttcg tttgtattct     2580

acctttgtaa aacagcctat agatgatgat gtgtttggga tactgcttat tttatgatag     2640

tttgtcctgt gtccttagtg atgtgtgtgt gtctccatgc acatgcacgc cgggattcct     2700

ctgctgccat ttgaattaga agaaaataat ttatatgcat gcacaggaag atattggtgg     2760

ccggtggttt tgtgctttaa aaatgcaata tctgaccaag attcgccaat ctcatacaag     2820

ccatttactt tgcaagtgag atagcttccc caccagcttt attttttaac atgaaagctg     2880

atgccaaggc caaaagaagt ttaaagcatc tgtaaatttg gactgttttc cttcaaccac     2940

catttttttt gtggttatta tttttgtcac ggaaagcatc ctctccaaag ttggagcttc     3000

tattgccatg aaccatgctt acaaagaaag cacttcttat tgaagtgaat tcctgcattt     3060

gatagcaatg taagtgccta taaccatgtt ctatattctt tattctcagt aacttttaaa     3120

agggaagtta tttatatttt gtgtataatg tgctttattt gcaaatcacc cactccttta     3180

caaccatact ttatatatgt acatacattc atactgtaga aaccagctca tgtgtacctc     3240

atatcccatc cttaagagaa gaaatgttat aaagtagaac taaatataaa ttttcagaat     3300

taatgcattc aaagtaatat atcaaatcca ggactttgtt aacttcaggt aaaaacttca     3360

ttagggtaat atcatctcaa ttttttcaaa tgaaaggatt ctctaattag aaatttatat     3420

gtcagagctg ttataaattt atcaactgtc aaatatgttc tggacagcta aatcatttga     3480

gatttttggt tttttgattt ctattcccta acttgtgaag acaatgaaaa atcaggcaga     3540

aatatttagt atctagtcag tatctgtagc tacactgtat aactgttctt caataaaatg     3600

gttcatattt tatagaaaaa aaaaaaaaaa a                                    3631


<210>  837
<211>  2757
<212>  DNA
<213>  homo sapiens

<400>  837
aaactttcgt gcgcgttgaa agctgctggc gcggcggggc ggactccacc cctgcccggc       60

agcccagcgc ctccggccgc acttccagct ctctgcgcag cccgccgcgc agcccgccgc      120

cccagccatg gcgaagcccc tgacggacca ggagaagcgg cggcagatca gcatccgcgg      180

catcgtgggc gtggagaacg tggcagagct gaagaagagt ttcaaccggc acctgcactt      240

cacgctggtc aaggaccgca acgtggccac cacccgcgac tactacttcg cgctggcgca      300

cacggtgcgc gaccacctgg tggggcgctg gatccgcacg cagcagcact actacgacaa      360

gtgccccaag cttggattgg atatagaaga gttagaagaa attgaagaag atgctggact      420

tggcaatggt ggtcttggga gacttgctgc ctgcttcttg gattccatgg caaccctggg      480

acttgcagcc tatggatacg gcattcggta tgaatatggg attttcaatc agaagatccg      540

agatggatgg caggtagaag aagcagatga ttggctcaga tatggaaacc cttgggagaa      600

gtcccgccca gaattcatgc tgcctgtgca cttctatgga aaagtagaac acaccaacac      660

cgggaccaag tggattgaca ctcaagtggt cctggctctg ccatatgaca cccccgtgcc      720

cggctacatg aataacactg tcaacaccat gcgcctctgg tctgctcggg caccaaatga      780

ctttaacctc agagacttta atgttggaga ctacattcag gctgtgctgg accgaaacct      840

ggccgagaac atctcccggg tcctctatcc caatgacaat ttttttgaag ggaaggagct      900

aagattgaag caggaatact ttgtggtggc tgcaaccttg caagatatca tccgccgttt      960

caaagcctcc aagtttggct ccacccgtgg tgcaggaact gtgtttgatg ccttcccgga     1020

tcaggtggcc atccagctga atgacactca ccctgcactc gcgatccctg agctgatgag     1080

gatttttgtg gatattgaaa aactgccctg gtccaaggca tgggagctca cccagaagac     1140

cttcgcctac accaaccaca cagtgctccc ggaagccctg gagcgctggc ccgtggacct     1200

ggtggagaag ctgctccctc gacatttgga aatcatttat gagataaatc agaagcattt     1260

agatagaatt gtggccttgt ttcctaaaga tgtggaccgt ctgagaagga tgtctctgat     1320

agaagaggaa ggaagcaaaa ggatcaacat ggcccatctc tgcattgtcg gttcccatgc     1380

tgtgaatggc gtggctaaaa tccactcaga catcgtgaag actaaagtat tcaaggactt     1440

cagtgagcta gaacctgaca agtttcagaa taaaaccaat gggatcactc caaggcgctg     1500

gctcctactc tgcaacccag gacttgcaga gctcatagca gagaaaattg gagaagacta     1560

tgtgaaagac ctgagccagc tgacgaagct ccacagcttc ctgggtgatg atgtcttcct     1620

ccgggaactc gccaaggtga agcaggagaa taagctgaag ttttctcagt tcctggagac     1680

ggagtacaaa gtgaagatca acccatcctc catgtttgat gtccaggtga agaggataca     1740

tgagtacaag cgacagctct tgaactgtct gcatgtgatc acgatgtaca accgcattaa     1800

gaaagaccct aagaagttat tcgtgccaag gacagttatc attggtggta aagctgcccc     1860

aggatatcac atggccaaaa tgatcataaa gctgatcact tcagtggcag atgtggtgaa     1920

caatgaccct atggttggaa gcaagttgaa agtcatcttc ttggagaact acagagtatc     1980

tcttgctgaa aaagtcattc cagccacaga tctgtcagag cagatttcca ctgcaggcac     2040

cgaagcctcg gggacaggca atatgaagtt catgctaaat ggggccctaa ctatcgggac     2100

catggatggg gccaatgtgg aaatggcaga agaagctggg gaagagaacc tgttcatctt     2160

tggcatgagg atagatgatg tggctgcttt ggacaagaaa gggtacgagg caaaagaata     2220

ctatgaggca cttccagagc tgaagctggt cattgatcaa attgacaatg gctttttttc     2280

tcccaagcag cctgacctct tcaaagatat catcaacatg ctattttatc atgacaggtt     2340

taaagtcttt gcagactacg aagcctatgt caagtgtcaa gataaagtga gtcagctgta     2400

catgaatcca aaggcctgga acacaatggt actcaaaaac atagctgcct cggggaaatt     2460

ctccagtgac cgaacaatta aagaatatgc ccaaaacatc tggaacgtgg aaccttcaga     2520

tctaaagatt tctctatcca atgaatctaa caaagtcaat ggaaattgaa ctctagaatt     2580

gtctctagaa aacatagctt cttactgaac ttgaacattt ttacaacatt cactggtttt     2640

tgttttgtta gctaataatc tataatagtt gagtatctct gggaatgggg agggaaatta     2700

tatgtaatag agcttaaaaa taaagtgtca atttccaagg gctaaaaaaa aaaaaaa        2757


<210>  838
<211>  3053
<212>  DNA
<213>  homo sapiens

<400>  838
gagcgcggct ggagtttgct gctgccgctg tgcagtttgt tcaggggctt gtggtggtga       60

gtccgagagg ctgcgtgtga gagacgtgag aaggatcctg cactgaggag gtggaaagaa      120

gaggattgct cgaggaggcc tggggtctgt gaggcagcgg agctgggtga aggctgcggg      180

ttccggcgag gcctgagctg tgctgtcgtc atgcctcaaa cccgatccca ggcacaggct      240

acaatcagtt ttccaaaaag gaagctgtct cgggcattga acaaagctaa aaactccagt      300

gatgccaaac tagaaccaac aaatgtccaa accgtaacct gttctcctcg tgtaaaagcc      360

ctgcctctca gccccaggaa acgtctgggc gatgacaacc tatgcaacac tccccattta      420

cctccttgtt ctccaccaaa gcaaggcaag aaagagaatg gtccccctca ctcacataca      480

cttaagggac gaagattggt atttgacaat cagctgacaa ttaagtctcc tagcaaaaga      540

gaactagcca aagttcacca aaacaaaata ctttcttcag ttagaaaaag tcaagagatc      600

acaacaaatt ctgagcagag atgtccactg aagaaagaat ctgcatgtgt gagactattc      660

aagcaagaag gcacttgcta ccagcaagca aagctggtcc tgaacacagc tgtcccagat      720

cggctgcctg ccagggaaag ggagatggat gtcatcagga atttcttgag ggaacacatc      780

tgtgggaaaa aagctggaag cctttacctt tctggtgctc ctggaactgg aaaaactgcc      840

tgcttaagcc ggattctgca agacctcaag aaggaactga aaggctttaa aactatcatg      900

ctgaattgca tgtccttgag gactgcccag gctgtattcc cagctattgc tcaggagatt      960

tgtcaggaag aggtatccag gccagctggg aaggacatga tgaggaaatt ggaaaaacat     1020

atgactgcag agaagggccc catgattgtg ttggtattgg acgagatgga tcaactggac     1080

agcaaaggcc aggatgtatt gtacacgcta tttgaatggc catggctaag caattctcac     1140

ttggtgctga ttggtattgc taataccctg gatctcacag atagaattct acctaggctt     1200

caagctagag aaaaatgtaa gccacagctg ttgaacttcc caccttatac cagaaatcag     1260

atagtcacta ttttgcaaga tcgacttaat caggtatcta gagatcaggt tctggacaat     1320

gctgcagttc aattctgtgc ccgcaaagtc tctgctgttt caggagatgt tcgcaaagca     1380

ctggatgttt gcaggagagc tattgaaatt gtagagtcag atgtcaaaag ccagactatt     1440

ctcaaaccac tgtctgaatg taaatcacct tctgagcctc tgattcccaa gagggttggt     1500

cttattcaca tatcccaagt catctcagaa gttgatggta acaggatgac cttgagccaa     1560

gaaggagcac aagattcctt ccctcttcag cagaagatct tggtttgctc tttgatgctc     1620

ttgatcaggc agttgaaaat caaagaggtc actctgggga agttatatga agcctacagt     1680

aaagtctgtc gcaaacagca ggtggcggct gtggaccagt cagagtgttt gtcactttca     1740

gggctcttgg aagccagggg cattttagga ttaaagagaa acaaggaaac ccgtttgaca     1800

aaggtgtttt tcaagattga agagaaagaa atagaacatg ctctgaaaga taaagcttta     1860

attggaaata tcttagctac tggattgcct taaattcttc tcttacaccc cacccgaaag     1920

tattcagctg gcatttagag agctacagtc ttcattttag tgctttacac attcgggcct     1980

gaaaacaaat atgacctttt ttacttgaag ccaatgaatt ttaatctata gattctttaa     2040

tattagcaca gaataatatc tttgggtctt actattttta cccataaaag tgaccaggta     2100

gacccttttt aattacattc actacttcta ccacttgtgt atctctagcc aatgtgcttg     2160

caagtgtaca gatctgtgta gaggaatgtg tgtatattta cctcttcgtt tgctcaaaca     2220

tgagtgggta tttttttgtt tgtttttttt gttgttgttg tttttgaggc gcgtctcacc     2280

ctgttgccca ggctggagtg caatggcgcg ttctctgctc actacagcac ccgcttccca     2340

ggttgaagtg attctcttgc ctcagcctcc cgagtagctg ggattacagg tgcccaccac     2400

cgcgcccagc taatttttta atttttagta gagacagggt tttaccatgt tggccaggct     2460

ggtcttgaac tcctgaccct caagtgatct gcccaccttg gcctccctaa gtgctgggat     2520

tataggcgtg agccaccatg ctcagccatt aaggtatttt gttaagaact ttaagtttag     2580

ggtaagaaga atgaaaatga tccagaaaaa tgcaagcaag tccacatgga gatttggagg     2640

acactggtta aagaatttat ttctttgtat agtatactat gttcatggtg cagatactac     2700

aacattgtgg cattttagac tcgttgagtt tcttgggcac tcccaagggc gttggggtca     2760

taaggagact ataactctac agattgtgaa tatatttatt ttcaagttgc attctttgtc     2820

tttttaagca atcagatttc aagagagctc aagctttcag aagtcaatgt gaaaattcct     2880

tcctaggctg tcccacagtc tttgctgccc ttagatgaag ccacttgttt caagatgact     2940

actttggggt tgggttttca tctaaacaca tttttccagt cttattagat aaattagtcc     3000

atatggttgg ttaatcaaga gccttctggg tttggtttgg tggcattaaa tgg            3053


<210>  839
<211>  4338
<212>  DNA
<213>  homo sapiens

<400>  839
aagattatag agacttgctt tagaaccaca agaagaaaga ggaggccggc ttttcagcta       60

gcatcatggc gtggccgtgc atcacgaggg cctgctgcat cgcccgcttc tggaaccagt      120

tggacaaagc ggacatcgct gtgccgctgg ttttcaccaa gtactcggag gccaccgagc      180

acccgggcgc cccgccgcag ccaccgccgc cgcagcagca ggcgcagccg gcgctcgcgc      240

ccccctcggc gcgcgcggtt gccatagaga cgcagccagc ccagggcgag ttggatgcag      300

ttgcccgggc aacggggcca gcgcctgggc ctaccggcga gcgcgagccg gcggcgggcc      360

ccggccggag cgggccgggc ccgggcctgg gctccggctc cacctccggc cccgcggact      420

cggtgatgcg gcaggattac cgagcctgga aggtgcagcg gcccgagccc agctgccggc      480

cgcgcagcga ataccagccc tccgacgctc ccttcgagcg cgagacccag taccagaagg      540

acttccgcgc ctggccgctg ccgcgccgcg gggaccaccc gtggatcccc aagcccgtgc      600

agatctctgc ggcctcccag gcgtcggcgc ccattctcgg ggcgcccaag cgccggccgc      660

agagccagga gcgctggcca gtgcaggccg ccgctgaggc ccgggagcag gaggcggccc      720

ccggcggagc gggtggcctg gcggccggaa aggcgtccgg ggcggacgag cgcgacacgc      780

gcaggaaggc cgggcctgcc tggattgtgc gccgcgccga gggcctgggg cacgagcaga      840

cgccgctgcc cgcggcccag gcccaggtcc aggccaccgg ccccgaggct ggcagggggc      900

gcgccgcggc ggacgccctc aaccggcaaa tccgcgagga ggtggcgagt gcagtgagca      960

gctcctacag gaatgaattc agggcatgga cggacatcaa gcctgtgaaa ccaataaagg     1020

ccaagcccca gtacaagccc ccagatgata agatggttca tgagaccagc tacagtgctc     1080

agttcaaagg agaggccagc aagccaacaa cagctgacaa taaggtcatt gatcgcagaa     1140

gaatacgcag cctctacagc gaacccttca aggaaccccc aaaggtggaa aaacctagtg     1200

ttcagagttc caaaccaaaa aagacctcag cgagccataa gcccacgagg aaggccaaag     1260

acaagcaggc ggtgtcaggc caggctgcca agaaaaagag cgcggagggc ccgagtacca     1320

ccaagccaga cgacaaggag caaagcaaag agatgaacaa taaactggct gaggcgaaag     1380

agtaaatttc cctgcacttt ccttttactc ttctctctct ctccctcccc ccaacttttt     1440

ttttttaaac caacaaacca aaaaaggcca caaaattaat tagaggcttc tcatctgcct     1500

tggtcctgag tgttccagga gctctttggt ttggcttctt ttgatggaag aatcctgctt     1560

cacagactga gtggcaggcc tcctcctgag ggcagcccct ggagcaccag gaagcgttgc     1620

cgctggctgt gccctcccct ggcactctga ctgcatgctg atgagcaagg caggcaggtc     1680

tgagaggcga aacgaatctc ccggcagtgc ttggaagtgt ctgtggggtc tcctcctccc     1740

agatccccaa gatctgtgtc actggtcgat tttgaacttt aggtacatgt gttcttttca     1800

aaaattcaga gaatcgtcat gtgccacaga agctcagcct gggcttcagc aattgacaaa     1860

atttgaagaa atattaaaca aaaataacaa aaaaagaaac aaccttggcc ttaatgtcaa     1920

taaaagggag ttgtgtctgt taagtggtct tttcatagaa tcgtccatta gaaatgtgtg     1980

cctgtgttta gcttcctatc agtgggcttt aaattgtata ccgagtcata gatacgccac     2040

tgataactaa aactagatca gggctggtga agaaggttag gtgttttagg tacattccag     2100

ctgtcatagg aagatcacag aaatgaggag gctgttttcc tctgattctc ctcggccgac     2160

cacctgtcca atgctgctgg tttcgcagag cgaccggttg gagatgtctg aggaagaaag     2220

ttcaaggtgt agggatagtg tgtttggaat ttgactttcc atttctgaga cccaaggggg     2280

cgtagatgta gtggcaagtg tggcgatgtt tactctccct tcctgaaccg ctctggtctg     2340

ctcctcagag agggcagcgg tgccaggcct caggtcaggg agaatgtctg tgacttagct     2400

gcagactagg agactgccct gctaactaat tagcaagcag ctttgacctc attaatatat     2460

aaaagcagct ctcagtatat tccgtgtcgt gtgtgtgtgt ggccaaagcc cccaagggtg     2520

gcaagtgcca ccttcgctgt gctagagttg tgttgtagga attagtcagg gagttgttgt     2580

gaaaaaaaaa accccagtgc ttgtgaggga actcaaaata gttaccagaa aaataatatt     2640

tgccaatatg acgtgtatat tgctcagcac actctgtatc tcctgtcctt aaaatcctct     2700

tgtccccggc attctgacac actgggctgc cgtccggtgt caagccccgg cgcaggcttg     2760

ctcttctttt acaatgaaag gggtgaagag tgagggtctc acagttcctt acctcaaagt     2820

ccctttaggt ccttctggtt tggaggaagt ggagcctcca cgaactctct cttactccga     2880

ccattcaggc agcaaagtct ctgcttacat cattttggtt gtcaccttgg ggctgagtga     2940

gaagtctttt gtaaattaat tcggcgtgtg ctacatgagc cataattatt aacagaacag     3000

gaatatcaga aacgaagttg ttgatcaggc ccactgcgac cttcctttct atctcagggt     3060

ttaaaactgt gaggaaggag aagtatgaag gaaggtagaa aatgctggtg ggtctccgtg     3120

tttatgagtc acagattttg aaagctatca ggaaatgact agagtggatc ctggcactga     3180

ttccaactct ttgccagcta atcttaacat ttagcagaaa gctctagcaa catgatctta     3240

attgtatcca gaggatttgc caatgtatgt tcagtctctc aagatttggc attagtcaga     3300

catgttgatg ctagccacaa tttggatttc tccatagaat aatcatttat ttttgcagat     3360

caaataaatc agagtttaca atgcacaggg gatcatttat ttagcattcc cttgctagaa     3420

gcccgtgtgc caggcactgt gctaggcgtg gtgggcagta taaagaaatc tgtctccaca     3480

gccacacaac cagagggtgc acatgacttg atccctatga ccaagtcaag ttggtgttgc     3540

ccaaatcgca gtttgacata agggtcccac aggcttcccc accccccgcc cccactcact     3600

gccccaggga ccaacttcct accctcaccc aaggctttag aggacctgta gcatgtcttt     3660

ttcaacctgt cagtatcccc ttctgcttaa cacacccact gagaaaaccc tgtttgtagt     3720

tcactttgac tcttgaatgt gtcactttac tggcaagaga cttcctttga tttctactgt     3780

ttacaaataa aactcagcca gtctcattct atatcccaaa cgtactgaat gaaactgatt     3840

ttggttccac aagcagtgtt tgggtgttgc cttcctgaag gtgaccaagc ttccaaagct     3900

cgtcccactg gcctctgtac atttccctgt ggttctccgt ccttccctgg cgagggagct     3960

gggactgaag ctttcccgct gtttccctgc ctgcaaaagc agccccaaga gctgcgcatt     4020

ggcttccctc agcaatctgt cctgtctgtg ctcccattcg gtccacatag ctttctttgc     4080

ctctctgagg cagacaggaa gtgtctaatt acgattttgt ggcctgggtt ttgttgcata     4140

ccacagattg tctatgtaac atgtagcgca cacctctctt ggtgctattt cattcctgct     4200

gtaagagaat gacaaaaata ttcatgtata gccaattgat tgtgacgtgc ttgtggtctg     4260

tgcttgctca gaaaaacaaa caaacaaaca gtttttccaa ttataaataa atgctaaaga     4320

cgaacaccaa aaaaaaaa                                                   4338


<210>  840
<211>  2666
<212>  DNA
<213>  homo sapiens

<400>  840
aagattatag agacttgctt tagaaccaca agaagaaaga ggaggccggc ttttcagcta       60

gcatcatggc gtggccgtgc atcacgaggg cctgctgcat cgcccgcttc tggaaccagt      120

tggacaaagc ggacatcgct gtgccgctgg ttttcaccaa gtactcggag gccaccgagc      180

acccgggcgc cccgccgcag ccaccgccgc cgcagcagca ggcgcagccg gcgctcgcgc      240

ccccctcggc gcgcgcggtt gccatagaga cgcagccagc ccagggcgag ttggatgcag      300

ttgcccgggc aacggggcca gcgcctgggc ctaccggcga gcgcgagccg gcggcgggcc      360

ccggccggag cgggccgggc ccgggcctgg gctccggctc cacctccggc cccgcggact      420

cggtgatgcg gcaggattac cgagcctgga aggtgcagcg gcccgagccc agctgccggc      480

cgcgcagcga ataccagccc tccgacgctc ccttcgagcg cgagacccag taccagaagg      540

acttccgcgc ctggccgctg ccgcgccgcg gggaccaccc gtggatcccc aagcccgtgc      600

agatctctgc ggcctcccag gcgtcggcgc ccattctcgg ggcgcccaag cgccggccgc      660

agagccagga gcgctggcca gtgcaggccg ccgctgaggc ccgggagcag gaggcggccc      720

ccggcggagc gggtggcctg gcggccggaa aggcgtccgg ggcggacgag cgcgacacgc      780

gcaggaaggc cgggcctgcc tggattgtgc gccgcgccga gggcctgggg cacgagcaga      840

cgccgctgcc cgcggcccag gcccaggtcc aggccaccgg ccccgaggct ggcagggggc      900

gcgccgcggc ggacgccctc aaccggcaaa tccgcgagga ggtggcgagt gcagtgagca      960

gctcctacag gaatgaattc agggcatgga cggacatcaa gcctgtgaaa ccaataaagg     1020

ccaagcccca gtacaagccc ccagatgata agatggttca tgagaccagc tacagtgctc     1080

agttcaaagg agaggccagc aagccaacaa cagctgacaa taaggtcatt gatcgcagaa     1140

gaatacgcag cctctacagc gaacccttca aggaaccccc aaaggtggaa aaacctagtg     1200

ttcagagttc caaaccaaaa aagacctcag cgagccataa gcccacgagg aaggccaaag     1260

acaagcaggc ggtgtcaggc caggctgcca agaaaaagag cgcggagggc ccgagtacca     1320

ccaagccaga cgacaaggag caaagcaaag agatgaacaa taaactggct gaggcgaaag     1380

agagcctggc tcaacccgtc agtgattcaa gtaagactca aggtcctgta gccacagagc     1440

cagacaagga tcaaggttct gtggtcccag gccttctgaa aggtcaaggt cctatggtgc     1500

aagagcctct gaagaagcaa ggttctgtgg tcccagggcc tccaaaggat ctaggtccca     1560

tgatcccatt accagtcaag gatcaagatc acacggtccc tgagccttta aagaatgaaa     1620

gccctgttat ctcagcacca gtcaaggacc aaggtccctc ggtcccagtt cctccaaaga     1680

atcaaagtcc tatggttcca gcaaaagtta aggatcaagg ctctgtggta ccagagtctc     1740

taaaggatca aggtcctagg attcctgagc ctgtgaagaa tcaagctcct atggtcccag     1800

cacctgtcaa ggatgaaggt cccatggtct cagcatctgt caaggatcaa ggtcccatgg     1860

tctcagcacc tgtcaaggat caaggtccca tagtcccagc acctgtcaag ggtgaaggtc     1920

ccatagtccc agcacctgtc aaggatgaag gtcccatggt ctcagcacct atcaaggatc     1980

aagatcccat ggtcccagag catccgaagg atgaaagtgc catggccaca gcacccataa     2040

agaatcaagg ttccatggtc tctgagcctg taaagaatca aggtttagtg gtctcagggc     2100

cagtcaagga tcaagatgtt gtagtcccag agcatgcaaa ggttcacgat tctgcagttg     2160

tggcacctgt aaagaatcaa ggtcctgtgg tccccgagtc cgtgaagaat caagacccca     2220

ttctcccagt actagttaag gatcaaggcc ccacagtcct acagcctcca aagaatcaag     2280

gtcgtatagt ccctgaacct ctgaagaatc aagttcctat agtcccagtg cctctgaagg     2340

atcaagatcc tctggtgcca gtaccagcaa aggaccaagg tcctgcagtc cctgaacctc     2400

tgaagactca aggtcccagg gaccctcagc tacctactgt ctcacctcta ccccgagtca     2460

tgatcccaac tgccccccat acggaataca ttgagagctc cccttgacac tcaccccttg     2520

acacaccaat gaaggagctg acagtgagag tgctcccctc ccaggggcag tgaagacaca     2580

tatttaatct gcatgaaaca tgtacagtag tcttgctgga atctaataaa aatggtccct     2640

ctggctcaaa aaaaaaaaaa aaaaaa                                          2666


<210>  841
<211>  4338
<212>  DNA
<213>  homo sapiens

<400>  841
aagattatag agacttgctt tagaaccaca agaagaaaga ggaggccggc ttttcagcta       60

gcatcatggc gtggccgtgc atcacgaggg cctgctgcat cgcccgcttc tggaaccagt      120

tggacaaagc ggacatcgct gtgccgctgg ttttcaccaa gtactcggag gccaccgagc      180

acccgggcgc cccgccgcag ccaccgccgc cgcagcagca ggcgcagccg gcgctcgcgc      240

ccccctcggc gcgcgcggtt gccatagaga cgcagccagc ccagggcgag ttggatgcag      300

ttgcccgggc aacggggcca gcgcctgggc ctaccggcga gcgcgagccg gcggcgggcc      360

ccggccggag cgggccgggc ccgggcctgg gctccggctc cacctccggc cccgcggact      420

cggtgatgcg gcaggattac cgagcctgga aggtgcagcg gcccgagccc agctgccggc      480

cgcgcagcga ataccagccc tccgacgctc ccttcgagcg cgagacccag taccagaagg      540

acttccgcgc ctggccgctg ccgcgccgcg gggaccaccc gtggatcccc aagcccgtgc      600

agatctctgc ggcctcccag gcgtcggcgc ccattctcgg ggcgcccaag cgccggccgc      660

agagccagga gcgctggcca gtgcaggccg ccgctgaggc ccgggagcag gaggcggccc      720

ccggcggagc gggtggcctg gcggccggaa aggcgtccgg ggcggacgag cgcgacacgc      780

gcaggaaggc cgggcctgcc tggattgtgc gccgcgccga gggcctgggg cacgagcaga      840

cgccgctgcc cgcggcccag gcccaggtcc aggccaccgg ccccgaggct ggcagggggc      900

gcgccgcggc ggacgccctc aaccggcaaa tccgcgagga ggtggcgagt gcagtgagca      960

gctcctacag gaatgaattc agggcatgga cggacatcaa gcctgtgaaa ccaataaagg     1020

ccaagcccca gtacaagccc ccagatgata agatggttca tgagaccagc tacagtgctc     1080

agttcaaagg agaggccagc aagccaacaa cagctgacaa taaggtcatt gatcgcagaa     1140

gaatacgcag cctctacagc gaacccttca aggaaccccc aaaggtggaa aaacctagtg     1200

ttcagagttc caaaccaaaa aagacctcag cgagccataa gcccacgagg aaggccaaag     1260

acaagcaggc ggtgtcaggc caggctgcca agaaaaagag cgcggagggc ccgagtacca     1320

ccaagccaga cgacaaggag caaagcaaag agatgaacaa taaactggct gaggcgaaag     1380

agtaaatttc cctgcacttt ccttttactc ttctctctct ctccctcccc ccaacttttt     1440

ttttttaaac caacaaacca aaaaaggcca caaaattaat tagaggcttc tcatctgcct     1500

tggtcctgag tgttccagga gctctttggt ttggcttctt ttgatggaag aatcctgctt     1560

cacagactga gtggcaggcc tcctcctgag ggcagcccct ggagcaccag gaagcgttgc     1620

cgctggctgt gccctcccct ggcactctga ctgcatgctg atgagcaagg caggcaggtc     1680

tgagaggcga aacgaatctc ccggcagtgc ttggaagtgt ctgtggggtc tcctcctccc     1740

agatccccaa gatctgtgtc actggtcgat tttgaacttt aggtacatgt gttcttttca     1800

aaaattcaga gaatcgtcat gtgccacaga agctcagcct gggcttcagc aattgacaaa     1860

atttgaagaa atattaaaca aaaataacaa aaaaagaaac aaccttggcc ttaatgtcaa     1920

taaaagggag ttgtgtctgt taagtggtct tttcatagaa tcgtccatta gaaatgtgtg     1980

cctgtgttta gcttcctatc agtgggcttt aaattgtata ccgagtcata gatacgccac     2040

tgataactaa aactagatca gggctggtga agaaggttag gtgttttagg tacattccag     2100

ctgtcatagg aagatcacag aaatgaggag gctgttttcc tctgattctc ctcggccgac     2160

cacctgtcca atgctgctgg tttcgcagag cgaccggttg gagatgtctg aggaagaaag     2220

ttcaaggtgt agggatagtg tgtttggaat ttgactttcc atttctgaga cccaaggggg     2280

cgtagatgta gtggcaagtg tggcgatgtt tactctccct tcctgaaccg ctctggtctg     2340

ctcctcagag agggcagcgg tgccaggcct caggtcaggg agaatgtctg tgacttagct     2400

gcagactagg agactgccct gctaactaat tagcaagcag ctttgacctc attaatatat     2460

aaaagcagct ctcagtatat tccgtgtcgt gtgtgtgtgt ggccaaagcc cccaagggtg     2520

gcaagtgcca ccttcgctgt gctagagttg tgttgtagga attagtcagg gagttgttgt     2580

gaaaaaaaaa accccagtgc ttgtgaggga actcaaaata gttaccagaa aaataatatt     2640

tgccaatatg acgtgtatat tgctcagcac actctgtatc tcctgtcctt aaaatcctct     2700

tgtccccggc attctgacac actgggctgc cgtccggtgt caagccccgg cgcaggcttg     2760

ctcttctttt acaatgaaag gggtgaagag tgagggtctc acagttcctt acctcaaagt     2820

ccctttaggt ccttctggtt tggaggaagt ggagcctcca cgaactctct cttactccga     2880

ccattcaggc agcaaagtct ctgcttacat cattttggtt gtcaccttgg ggctgagtga     2940

gaagtctttt gtaaattaat tcggcgtgtg ctacatgagc cataattatt aacagaacag     3000

gaatatcaga aacgaagttg ttgatcaggc ccactgcgac cttcctttct atctcagggt     3060

ttaaaactgt gaggaaggag aagtatgaag gaaggtagaa aatgctggtg ggtctccgtg     3120

tttatgagtc acagattttg aaagctatca ggaaatgact agagtggatc ctggcactga     3180

ttccaactct ttgccagcta atcttaacat ttagcagaaa gctctagcaa catgatctta     3240

attgtatcca gaggatttgc caatgtatgt tcagtctctc aagatttggc attagtcaga     3300

catgttgatg ctagccacaa tttggatttc tccatagaat aatcatttat ttttgcagat     3360

caaataaatc agagtttaca atgcacaggg gatcatttat ttagcattcc cttgctagaa     3420

gcccgtgtgc caggcactgt gctaggcgtg gtgggcagta taaagaaatc tgtctccaca     3480

gccacacaac cagagggtgc acatgacttg atccctatga ccaagtcaag ttggtgttgc     3540

ccaaatcgca gtttgacata agggtcccac aggcttcccc accccccgcc cccactcact     3600

gccccaggga ccaacttcct accctcaccc aaggctttag aggacctgta gcatgtcttt     3660

ttcaacctgt cagtatcccc ttctgcttaa cacacccact gagaaaaccc tgtttgtagt     3720

tcactttgac tcttgaatgt gtcactttac tggcaagaga cttcctttga tttctactgt     3780

ttacaaataa aactcagcca gtctcattct atatcccaaa cgtactgaat gaaactgatt     3840

ttggttccac aagcagtgtt tgggtgttgc cttcctgaag gtgaccaagc ttccaaagct     3900

cgtcccactg gcctctgtac atttccctgt ggttctccgt ccttccctgg cgagggagct     3960

gggactgaag ctttcccgct gtttccctgc ctgcaaaagc agccccaaga gctgcgcatt     4020

ggcttccctc agcaatctgt cctgtctgtg ctcccattcg gtccacatag ctttctttgc     4080

ctctctgagg cagacaggaa gtgtctaatt acgattttgt ggcctgggtt ttgttgcata     4140

ccacagattg tctatgtaac atgtagcgca cacctctctt ggtgctattt cattcctgct     4200

gtaagagaat gacaaaaata ttcatgtata gccaattgat tgtgacgtgc ttgtggtctg     4260

tgcttgctca gaaaaacaaa caaacaaaca gtttttccaa ttataaataa atgctaaaga     4320

cgaacaccaa aaaaaaaa                                                   4338


<210>  842
<211>  1187
<212>  DNA
<213>  homo sapiens

<400>  842
gccctgcagg cgctgcggac aggggaagca cagagattcc ccgccgcgtt ccctggactc       60

aggagctcgc cgcgatgccc cgccccactc tccacccgct gaatgcaggg cgcatgctgc      120

tacttggcgg ctcaagcccc gcccgcaccg tccccattct ctgaccgccc ctctcccggt      180

acactgcgca ggcacaacag agccgctccc ctctcctcgc cccgccaccg ggacggagag      240

cgcccgccgc tgcatttccg gcgacacctc gcagtcattc ctgcggcttg cgcgcccttg      300

tagacagccg gggccttcgt gagaccggtg caggcctggg gtagtctcct gtctggacag      360

agaagagaaa aatgcaggac actggctcag tagtgccttt gcattggttt ggctttggct      420

acgcagcact ggttgcttct ggtgggatca ttggctatgt aaaagcaggc agcgtgccgt      480

ccctggctgc agggctgctc tttggcagtc tagccggcct gggtgcttac cagctgtctc      540

aggatccaag gaacgtttgg gttttcctag ctacatctgg taccttggct ggcattatgg      600

gaatgaggtt ctaccactct ggaaaattca tgcctgcagg tttaattgca ggtgccagtt      660

tgctgatggt cgccaaagtt ggagttagta tgttcaacag accccattag cagaagtcat      720

gttccagctt agactgatga agaattaaaa atctgcatct tccactattt tcaatatatt      780

aagagaaata agtgcagcat ttttgcatct gacattttac ctaaaaaaaa agacaccaaa      840

cttggcagag aggtggaaaa tcagtcatga ttacaaacct acagaggtgg cgagtatgta      900

acacaagagc ttaataagac cctcatagag cttgattctt gtatattgat gttgtctttt      960

ctttctgtat ctgtaggtaa atctcaaggg taaaatgtta ggtgtcagct ttcagggctc     1020

tgaaacccca ttccctgctc tgaggaacag tgtgaaaaaa agtcttttag gagatttaca     1080

atatctgttc ttttgctcat cttagaccac agactgactt tgaaattatg ttaagtgaaa     1140

tatcaatgaa aataaagttt actataaata ataaaaaaaa aaaaaaa                   1187


<210>  843
<211>  1876
<212>  DNA
<213>  homo sapiens

<400>  843
ggggaatcct gctctgggat agcacccggc cccgcagagc agcgcggcag cccaagggcc       60

ccggcgccgg gggcggcggg gaaccccaaa cgcaaccggg tctggaggga tccccgcgcc      120

gagccagccg ccgtcaccgc ctccgcgccg cccctgcggg cttggcaggc gcccggcgcg      180

cccgcactgc gcccggccgc cggctcccgc ggtcccaccg tgagctcgcc ggcccgtcgc      240

ccgctcgcca tgcaaccgcc gccggcctcg cgcgcgtagg cgcccgccgc aggccatgct      300

gcccctgctc gccgcgctcc tggccgccgc ctgcccgctg ccgcccgtcc gcggcggggc      360

cgcggacgcg cccggcctcc tcggggtgcc ctccaatgct tcagtcaacg cgtcctccgc      420

ggacgagccc atcgccccgc ggctgctggc ctcggcggcc cccgggcccc ccgagcgccc      480

gggcccggag gaggcggcgg cggcggcggc gccgtgcaac atcagcgtgc agcggcagat      540

gctgagctcg ctgctcgtgc gctggggccg cccgcggggc ttccagtgcg acctactgct      600

cttctccacc aacgcgcacg gccgcgcttt cttcgccgcc gccttccacc gcgtcgggcc      660

gccgctgctc atcgagcacc tggggctggc ggcgggcggc gcgcagcagg acctgcgcct      720

ctgcgtgggc tgcggctggg tgcgcggtcg ccgcaccggc cgcctccggc ccgccgccgc      780

ccccagcgcc gccgccgcca ccgccggggc gcccaccgcg ctgccagcct accccgcggc      840

cgagccgccc gggccgctgt ggctgcaggg cgagccgctg catttctgct gcctagactt      900

cagcctggag gagctgcagg gcgagccggg ctggcggctg aaccgtaagc ccattgagtc      960

cacgctggtg gcctgcttca tgaccctggt catcgtggtg tggagcgtgg ccgccctcat     1020

ctggccggtg cccatcatcg ccggcttcct gcccaacggc atggaacagc gccggaccac     1080

cgccagcacc accgcagcca cccccgccgc agtgcccgca gggaccaccg cagccgccgc     1140

cgccgccgcc gctgccgccg ccgccgcggc cgtcacttcg ggggtggcga ccaagtgacc     1200

cgctccgctc ctccctgtgt ccgtcctgtg tccgcgcgcg cgggtgcctt tcccgccgga     1260

gactcggccg gtgtgcttcg tgctgtagtt atcgttagtt cctcttcccg agatggggcc     1320

gccgagagac cccagcgcct ttgaaaagca aggtttgtgc tgcgcttcca gttccgaaaa     1380

gcagatgttt aagcccttgg actgagggtg ggatcgcagc tccgaagacg gagaggaggg     1440

aaatggggcc ctttcccctc tattgcatcc ccctgcccga ctccttcccc gcacccacgt     1500

gccctagatt catggcagaa aatgaccaaa tcctgtgtat ttgttttata tatttaataa     1560

ctgttttaaa tgaaagtttt agtaaaaaaa atacaaaaca aaaagattaa attgctattg     1620

ctgtagtaag agaagctctt tgtatctgaa catagttgta tttgaaattt gtggtttttt     1680

aatttattta aaattggggg gagggcatgg gaaggattta acaccgatat attgttaccg     1740

ctgaaaatga actttatgaa ccttttccaa gttgatctat ccagtgacgt ggcctggtgg     1800

gcgtttcttc ttgtacttat gtggtttttt ggcttttaat acagacattt tcctccagaa     1860

aaaaaaaaaa aaaaaa                                                     1876


<210>  844
<211>  1868
<212>  DNA
<213>  homo sapiens

<400>  844
ggaagcgagg gtgcggcgca atccggagag gacgccagga cgacgcccga gttccctttc       60

aggctagaac tcttcctttt tctagcttgg ggtagaaggc ggagccggag ccccggaacc      120

cccgccctcg gggtgcgagg cggcagcagg gccgtcccct acatttgcat agcccctggg      180

acgtggcgct gcacccaagc ctcttctcag ttggagggaa ctccaagtcc cacagtgcca      240

cggggtgggg tgcgtcactt tcgctgcgtt ggaggctgag gagaattgag cctgggaggc      300

gggtccggag agggctatgg aaagccgccg gcggggaatc ccggccgtag agggacagtg      360

gataggtgcc cgaggcctac agctggcctg gggctcgtgt ctgggcttcg gacgttgggg      420

cccggtggcc caccctttcc gtagttgtcc caaatggagc tggaattgga tgctggtgac      480

caagacctgc tggccttcct gctagaggaa agtggagatt tggggacggc acccgatgag      540

gccgtgaggg ccccactgga ctgggcgctg ccgctttctg aggtaccgag cgactgggaa      600

gtagatgatt tgctgtgctc cctgctgagt cccccagcgt cgttgaacat tctcagctcc      660

tccaacccct gccttgtcca ccatgaccac acctactccc tcccacggga aactgtctct      720

atggatctag agagtgagag ctgtagaaaa gaggggaccc agatgactcc acagcatatg      780

gaggagctgg cagagcagga gattgctagg ctagtactga cagatgagga gaagagtcta      840

ttggagaagg aggggcttat tctgcctgag acacttcctc tcactaagac agaggaacaa      900

attctgaaac gtgtgcggag gaagattcga aataaaagat ctgctcaaga gagccgcagg      960

aaaaagaagg tgtatgttgg gggtttagag agcagggtct tgaaatacac agcccagaat     1020

atggagcttc agaacaaagt acagcttctg gaggaacaga atttgtccct tctagatcaa     1080

ctgaggaaac tccaggccat ggtgattgag atatcaaaca aaaccagcag cagcagcacc     1140

tgcatcttgg tcctactagt ctccttctgc ctcctccttg tacctgctat gtactcctct     1200

gacacaaggg ggagcctgcc agctgagcat ggagtgttgt cccgccagct tcgtgccctc     1260

cccagtgagg acccttacca gctggagctg cctgccctgc agtcagaagt gccgaaagac     1320

agcacacacc agtggttgga cggctcagac tgtgtactcc aggcccctgg caacacttcc     1380

tgcctgctgc attacatgcc tcaggctccc agtgcagagc ctcccctgga gtggccattc     1440

cctgacctct tctcagagcc tctctgccga ggtcccatcc tccccctgca ggcaaatctc     1500

acaaggaagg gaggatggct tcctactggt agcccctctg tcattttgca ggacagatac     1560

tcaggctaga tatgaggata tgtggggggt ctcagcagga gcctgggggg ctccccatct     1620

gtgtccaaat aaaaagcggt gggcaagggc tggccgcagc tcctgtgccc tgtcaggacg     1680

actgagggct caaacacacc acacttaatg gctttctggg tcttttattt gtacccatgt     1740

gtctgtcaca ccatgaatgt acctggggaa atcaactgac ctccctgaac atttcacgca     1800

gtcagggaac aggtgaggaa agaaataaat aagtgattct aatgctgcct aaaaaaaaaa     1860

aaaaaaaa                                                              1868


<210>  845
<211>  4475
<212>  DNA
<213>  homo sapiens

<400>  845
gtgggtccct gtgacgtcac tgccggccgg acgccatctt gctggtttgc ggccggtctt       60

ggatgaagcg gcggccgtgg tgagagcgtg gggaagggtg gggtgagggg gcgaggccgc      120

agctagggcg gcgaaactct cctcccctcg gccccaccgc gtgggacggc gtgaacgtgg      180

tgtcggaggg atgtcagcct tctctgaggc ggcgctggag aagaagctgt cggagttgag      240

caactcgcag cagagcgtgc agaccttgtc cctgtggctc attcaccacc gtaaacactc      300

gcgtcccatc gtcaccgtgt gggagcggga gctgcggaaa gccaaaccaa acaggaagct      360

tacttttctc tacctagcca atgatgtcat acagaacagc aagaggaagg ggccagagtt      420

tacaaaagat tttgcaccag ttatagtgga ggcttttaag catgtttcaa gtgaaactga      480

tgaaagttgt aagaagcacc ttggaagagt gttatctatt tgggaagaaa ggtctgttta      540

tgaaaatgat gtattagaac aacttaaaca agctctgtat ggtgataaga agcctaggaa      600

gcgaacttat gaacagataa aggtggatga aaatgaaaac tgttcctctc tgggatctcc      660

aagtgaacca ccacagactc tagatctcgt tagagcatta caagatctgg aaaatgcagc      720

ctcaggtgat gcagcagttc atcagaggat agcttcttta cctgttgaag tccaagaagt      780

atctctatta gataaaataa cagataaaga atctggagaa aggctttcca aaatggtaga      840

ggatgcgtgt atgttgctgg cagattacaa tggcagattg gcggcagaaa tagatgatag      900

aaagcaactc actcgaatgt tagcagattt tcttcgttgt caaaaggaag cccttgcaga      960

gaaagagcat aaattggaag agtacaagcg caagctagcc agagtttccc tggtgcgcaa     1020

agaactcagg tcccggatcc agagcctgcc agacttatct cgattgccca atgtcactgg     1080

cagccacatg cacctgccct ttgcgggaga catctacagt gaagattgat ggaccagcct     1140

ctttccaggt cccaggactt tgcaagagat ggagacaggt taggtggata gtcctgtagt     1200

gttatttttg tatattgttg agaaagaaac actaacaaaa ggaacaacga gtaatttata     1260

aaattgttta aaatgttggt ttgtttacta ttttattggt aaattaacat gacttaattt     1320

gaacaaagtg atgatttgtg tgtattaata agctcacaaa tagtgattat tttcaaaaga     1380

tctttttgta aatttttttt ttgatccaag gccttgtgag aaatctcttg tttgtatttc     1440

ttcaggtatt ttcaattgtt tttctttatt ttcttcagca tttaatcact gtatactatg     1500

taattcctga aggggaagaa ctaattagga gttgattgag actttattat ggtatagtta     1560

ggacttgatt gtagaaggga ctaaatgttc caacataatc tttacccttc tccccaaaca     1620

aaatatcaat tctgtgtctc tacatgcctt tgattcctta gaggtcggta atttaacata     1680

aaacagggat gtcactttga ggggcagatg aaagtctaga gaactgttcc ttaatagcat     1740

tgtaaaagtt ccattccaac tgccagtgta gattttaaaa gtgttaaata gtgactccct     1800

tgattaaact gtttgtaatt atttgagtag attaataatg aaaatacttt ggaaataata     1860

tacattttga cattctacca agaggacaac tttggttctg gaactggttt ctatttgtca     1920

aatcagtttc cttttaacat aattaatccc tttaacaaaa agccgtctat gggattaaaa     1980

gacacgtgaa atgatacttt tattattccc ttgctcatat aactttaaaa ataatacttt     2040

tagctctaat agctcaagaa cacaatattc gttaatgttc agtaaagtag cctgagacat     2100

tttcaatgtt tccttaaggt ttttgaatga ctgtatattt ggcagttaag cagtgccaca     2160

ctacagggta gatatggtaa attttatatt tgtatattta cagttacaaa acaaatgtac     2220

ttttaccttt tatttctgac cctgtgtgtt agagcagttg catgctctcc tgctgttaaa     2280

aacacattgt taagctgtgg atttgtactc aataatgact taggataaac atttattttc     2340

attcattgct ttacatacta gacatttttc ttctctttgt aagtagattc aaattagata     2400

gtcaataaaa catcttgaaa atcccacaag ccaattatgt ctctctagtc tgaatggctt     2460

cattgtttct ttctcagtat tagaaattat agttacaatg aattgcatat gaagaaggca     2520

gacatttatt tttaatagcc aagtagttct gcaaatagtt cttttaacaa tttgacctct     2580

ctccaaaaca gagacacata taagtagtgc tcatccatgc actactaata atacatggct     2640

tattccaaag tttttagtca acttttggga cttggggtgc attttctcac agaaagaata     2700

gtagttaggt tccctaacac taccgctgat agctcacctg ggaactgaat ccacctaacc     2760

atgaatgtcc ttcacttgta acgtggttca caggttacta atcatagatc ctgaccagca     2820

tttgtaacac tgctctaact aggacacagc atgcagcagc cacactcaca ccctgggatg     2880

tctgtgtacc tctgtcccta ggtgtaggaa atggaagaaa aagattcagc caagtgggga     2940

ggtgacagat gcacaattat gaaacctggt tgtacatgtt atgaaagtat actaagtaag     3000

ttagttttta ttattaatgt gaaagcaaaa acttgtatgt taacttattt tcaatatctt     3060

gaccttattt atgatctgct aaagtggtga tttatccatt caaaatatat atttttttcc     3120

atttaaaact aatttataaa ctatgtactc ctgggaagat ttgaaatctt ttagaagttt     3180

gttgaaatat tttcaccatt tcagacagac ttctgactta gatactgatt ttaatgccag     3240

tatctgctct aaatatttat gataaaaatg cattattttt ttaaagagct tgatgagatt     3300

tgtgataagt gatagtactc aaaaacctga atcccacccc tcgaccaatc ctccacaaac     3360

ttcagttgtt ggttaacgta ttaactgaac acagacaata cagtctgatt tagaagtcat     3420

cttttcagcc gtgtgataat taacatggta agccttagca gcaaacattc ttcctaaaag     3480

gaagacttca ttttctcaag aaatgggatt agttgggggt attataatac caaattgtaa     3540

atcatgagcg ttttctccac tgtgcacctg aggcagatca tgcatctttg agtgcagttt     3600

ggtctgaccc ctcaagagaa aagcatggtg ccgtagggct gctatggttt gaatggatgc     3660

catcactctt ttctccacat acagtgcaga gagctgtctg gagtcacaat ctgaacagat     3720

tctcgggcgc tccttctctc cttccatcac tacagtaagt aaaaggacca tagaggggaa     3780

ccaggaatct gagaatcagc tgtgctcaat agccaacctc cctgtccaga tgcagctatt     3840

ttggtatctc ctatcacatg cactctgaat cagggttttt ctataagaaa tctttcagaa     3900

tcagcaaaag tggggatgac ccaggcatct tgatttgcaa aatcacaaaa ctaagttgtc     3960

agttatcact gtagatgagc aactcatctt tttaaagtat agttactgaa ctgattctga     4020

gaaatcttta gagagaaaaa actcaacagt acaaattaac taattgggaa agttagaatg     4080

tcctttctga atttttcatt aaaaaaatta cattatctga aataacataa agctactaaa     4140

ctgctttgta ttctattaag aaatagctcc taaggatgta gtcttgtttc atagttgttg     4200

cactatatca aaacttaaaa tgtaagccca gttcttctct gtatagaaag gaaacattgt     4260

gttacttaat gaattattta tacagagcat ttgttgccaa ctgttgttcc agccatccac     4320

acaggagtct gttctgaggt ggcaatagca catgggaaga tgaactttcc ctgtttgttt     4380

acccgttctt ctttggctgt atctgatgac agtataagat gttcttaata aagttttatg     4440

ttctttttga aatgtgaaaa aaaaaaaaaa aaaaa                                4475


<210>  846
<211>  5149
<212>  DNA
<213>  homo sapiens

<400>  846
gagacaccac tgaatacaga gcagcgagca ctgaaggctt ccctctttcc ttaaacctgt       60

cgggttgtgg gctctctctt ttcccctctt gctcctttct tttctttttt tctgtttttt      120

taaaccttcc aaggcaagtt catggatact aagctgatgt gtttgttgtt ctttttctcc      180

ctgcctccgc tcctagtgag taaccacact ggccgcatca aggtggtctt tactccgagc      240

atctgtaaag tgacctgcac caagggcagc tgtcagaaca gctgtgagaa ggggaacacc      300

accactctca ttagtgagaa tggtcatgct gccgacaccc tgacggccac gaacttccga      360

gtggtaattt gccatcttcc atgtatgaat ggtggccagt gcagttcaag ggacaaatgt      420

cagtgccctc caaatttcac aggaaaactt tgtcagatcc cagtccatgg tgccagcgtg      480

cctaaacttt atcagcattc ccagcagcca ggcaaggcgt tggggacgca tgtcatccat      540

tcaacacata ccttgcctct gaccgtgact agccagcaag gagtcaaagt gaaatttcct      600

cctaacatag tcaatatcca tgtgaaacat cctcctgaag cttccgtcca gatacatcag      660

gtttcaagaa ttgatggccc aacaggccag aagacaaaag aagctcaacc aggccaatcc      720

caagtctcgt accaagggct tcctgtccag aagacccaga ccatacattc cacatactcc      780

caccagcagg tcattcctca cgtctacccc gtggctgcta agacacagct tggccggtgc      840

ttccaggaaa ccattgggtc acagtgtggc aaagcgctcc ctggcctttc aaagcaagag      900

gactgctgtg gaactgtggg tacctcctgg ggctttaaca aatgccagaa atgccccaag      960

aaaccatctt atcatggata caaccaaatg atggaatgcc taccgggtta taagcgggtt     1020

aacaacacct tttgccaaga tattaatgaa tgtcagctac aaggtgtatg ccctaatggt     1080

gagtgtttga ataccatggg cagctatcga tgtacctgca aaataggatt tgggccggat     1140

cctacctttt caagttgtgt tcctgatccc cctgtgatct cggaagagaa agggccctgt     1200

taccgacttg tcagttctgg aagacagtgt atgcaccctc tgtctgttca cctcaccaag     1260

cagctctgct gttgtagtgt gggcaaggcc tggggcccac actgtgagaa atgtcccctt     1320

ccaggcacag ccaaggaaga gccagtggag gccctgacct tctcccggga acacgggcca     1380

ggagtggcgg agccagaagt ggcaactgca ccccctgaaa aggaaatacc ttcattggat     1440

caagagaaaa ccaaacttga gcctggtcaa ccccagctgt ctccaggcat ttccactatt     1500

catctgcatc cacagtttcc agtagtgatt gaaaaaacat cacctcctgt gcctgttgaa     1560

gtagctcctg aagcttctac gtctagtgcc agccaagtga ttgctcctac tcaagtgaca     1620

gaaatcaatg aatgtactgt gaaccctgat atctgtggag caggacactg cattaaccta     1680

ccagtgagat atacctgtat atgctacgag ggctacaggt tcagtgaaca acagaggaaa     1740

tgtgtggata ttgatgagtg tactcaggtc caacacctct gctcccaggg ccgctgtgaa     1800

aacaccgagg gaagtttctt gtgcatttgc ccagcaggat ttatggccag tgaggagggt     1860

actaactgca tagatgttga cgaatgcctg aggccggacg tctgtgggga ggggcactgt     1920

gtcaatactg tgggggcctt ccggtgtgaa tactgtgaca gcgggtaccg catgactcag     1980

agaggccgtt gtgaggatat tgatgaatgt ttgaatccaa gcacttgtcc agatgagcag     2040

tgtgtgaatt ctcctggatc ttaccagtgc gttccctgca cagaaggatt ccgaggctgg     2100

aatggacagt gccttgatgt ggacgagtgc ctggaaccaa acgtctgcgc aaatggtgat     2160

tgttccaacc ttgaaggctc ctacatgtgt tcatgccaca aaggctatac ccggactccg     2220

gaccacaagc actgtagaga tattgatgaa tgtcagcaag ggaatctatg tgtaaacggg     2280

cagtgcaaaa ataccgaggg ctccttcagg tgcacctgtg gacaggggta ccagctgtcg     2340

gcagctaaag accagtgtga agacattgat gaatgccagc accgtcatct ctgtgctcat     2400

gggcagtgca ggaacactga gggctctttt caatgtgtgt gtgaccaggg ttacagagca     2460

tctgggcttg gagaccactg tgaagatatc aatgaatgct tggaggacaa gagtgtttgc     2520

cagagaggag actgcattaa tactgcaggg tcctatgatt gtacttgtcc ggatggattt     2580

cagctagatg acaataaaac atgtcaagat attaatgaat gtgaacatcc agggctctgt     2640

ggtccgcaag gggagtgcct aaacacagag ggttctttcc attgtgtctg ccagcagggt     2700

ttctcaatct ctgcagatgg ccgtacgtgt gaagatattg atgaatgtgt aaacaacact     2760

gtttgtgaca gtcacgggtt ttgtgacaat acagctggct ccttccgctg cctctgttat     2820

cagggctttc aagccccaca ggatgggcaa gggtgtgtgg atgtgaatga atgtgaactg     2880

ctcagtgggg tgtgtggtga agccttctgt gaaaacgtgg aagggtcctt cctgtgcgtg     2940

tgtgctgatg aaaaccaaga gtacagcccc atgactgggc agtgccgctc ccggacctcc     3000

acagatttag atgtagatgt agatcaaccc aaagaagaaa agaaagaatg ctactataat     3060

ctcaatgacg ccagtctctg tgataatgtg ttggccccca atgtcacgaa acaagaatgc     3120

tgctgtacat caggcgcggg atggggagat aactgcgaaa tcttcccctg cccggtcttg     3180

ggaactgctg agttcactga aatgtgtccc aaagggaaag gttttgtgcc tgctggagaa     3240

tcatcttctg aagctggtgg tgagaactat aaagatgcag atgaatgcct actttttgga     3300

caagaaatct gcaaaaatgg tttctgtttg aacactcggc ctgggtatga atgctactgt     3360

aagcaaggga cgtactatga tcctgtgaaa ctgcagtgct ttgatatgga tgaatgtcaa     3420

gaccccagta gttgtattga tggccagtgt gttaatacag agggctctta caactgcttc     3480

tgtactcacc ccatggtcct ggatgcgtca gaaaaaagat gtatacgacc ggctgagtca     3540

aacgaacaaa tagaagaaac tgatgtctac caagatttgt gctgggaaca tctgagtgat     3600

gaatacgtgt gtagccggcc tcttgtgggc aagcagacaa cgtacactga gtgctgctgt     3660

ctgtatggag aggcctgggg catgcagtgt gccctctgcc ccctgaagga ttcagatgac     3720

tatgctcagc tgtgtaacat ccccgtgacg ggacgccggc agccatatgg acgggacgcc     3780

ttggttgact tcagtgaaca gtatactcca gaagccgatc cctacttcat ccaagaccgt     3840

tttctaaata gctttgagga gttacaggct gaggaatgcg gcatcctcaa tggatgtgaa     3900

aatggtcgct gtgtgagggt ccaggaaggt tacacctgcg attgctttga tgggtatcac     3960

ttggatacgg ccaagatgac ctgtgtcgat gtaaatgaat gcgatgagtt gaacaaccgg     4020

atgtctctct gcaagaatgc caagtgcatt aacaccgatg gttcctacaa gtgtttgtgt     4080

ctgccaggct acgtgccttc tgacaagcca aactactgca ctccgttgaa taccgccttg     4140

aatttagaga aagacagtga cctggagtga aacagaatct acataaccta agcccatata     4200

ctctgcactg tgtaaaggaa aagggagaaa tgtattatac ttgagacatt gcacctaccc     4260

cggaaggctg gaaatacaga aacagcatgg aattgcaagt cctctgaaga caatgagagg     4320

atttaggatg agcccgatag gtgtggcaga ccaaatggac atttctctaa aaaaccagta     4380

tatatagtct gttcatatgt aaaattcaat ggaagagagg tggaacagtg ctgttatttt     4440

aaacagaagg ttgtattatt atgttgtttt gtttttttac tattgcttga ttaaatttgg     4500

catttaaata gtggtggaaa tattttatat aattttcatt ttttggttgt gcagttcctt     4560

ggctactgtt tttcttttac ttcagttttt taaaaatctc aaatgaaaaa gtcttcgata     4620

caatattgtt aagctgtatt ataagtattg ttacacaggg ttatgcaatt cccggcctgg     4680

agcatttttg aaattcaaat tgtctgtcct gtggagcagg cagtgatttt gttccaaaac     4740

tttgtataca catttggaga aaagtacttt atattttcag tgttttgtct gattttaatg     4800

tccgttctta gccaagctgc tagcaggtgt taattggatc cctttccttc actgaaatgg     4860

aagagtttat aagcttacgt tagtattgta atatgtaaag taagcccaac aaaaattttt     4920

aaaaatttga tgatccccaa tatatctacc attgtatgtt aaataaatca ccatttttgt     4980

agaaaaaatt ctacctgaga gtaattgtca atgagtacat gtgtataagt tgtatcccac     5040

tctccccact tttatctttt ccagtggtct tctgttaatg tagtgtcttt tacaagttaa     5100

tcattaaatt tgttagatct tgttatgggc taaaaaaaaa aaaaaaaaa                 5149


<210>  847
<211>  5023
<212>  DNA
<213>  homo sapiens

<400>  847
gagacaccac tgaatacaga gcagcgagca ctgaaggctt ccctctttcc ttaaacctgt       60

cgggttgtgg gctctctctt ttcccctctt gctcctttct tttctttttt tctgtttttt      120

taaaccttcc aaggcaagtt catggatact aagctgatgt gtttgttgtt ctttttctcc      180

ctgcctccgc tcctagtgag taaccacact ggccgcatca aggtggtctt tactccgagc      240

atctgtaaag tgacctgcac caagggcagc tgtcagaaca gctgtgagaa ggggaacacc      300

accactctca ttagtgagaa tggtcatgct gccgacaccc tgacggccac gaacttccga      360

gtggtaattt gccatcttcc atgtatgaat ggtggccagt gcagttcaag ggacaaatgt      420

cagtgccctc caaatttcac aggaaaactt tgtcagatcc cagtccatgg tgccagcgtg      480

cctaaacttt atcagcattc ccagcagcca ggcaaggcgt tggggacgca tgtcatccat      540

tcaacacata ccttgcctct gaccgtgact agccagcaag gagtcaaagt gaaatttcct      600

cctaacatag tcaatatcca tgtgaaacat cctcctgaag cttccgtcca gatacatcag      660

gtttcaagaa ttgatggccc aacaggccag aagacaaaag aagctcaacc aggccaatcc      720

caagtctcgt accaagggct tcctgtccag aagacccaga ccatacattc cacatactcc      780

caccagcagg tcattcctca cgtctacccc gtggctgcta agacacagct tggccggtgc      840

ttccaggaaa ccattgggtc acagtgtggc aaagcgctcc ctggcctttc aaagcaagag      900

gactgctgtg gaactgtggg tacctcctgg ggctttaaca aatgccagaa atgccccaag      960

aaaccatctt atcatggata caaccaaatg atggaatgcc taccgggtta taagcgggtt     1020

aacaacacct tttgccaaga tattaatgaa tgtcagctac aaggtgtatg ccctaatggt     1080

gagtgtttga ataccatggg cagctatcga tgtacctgca aaataggatt tgggccggat     1140

cctacctttt caagttgtgt tcctgatccc cctgtgatct cggaagagaa agggccctgt     1200

taccgacttg tcagttctgg aagacagtgt atgcaccctc tgtctgttca cctcaccaag     1260

cagctctgct gttgtagtgt gggcaaggcc tggggcccac actgtgagaa atgtcccctt     1320

ccaggcacag ccaaggaaga gccagtggag gccctgacct tctcccggga acacgggcca     1380

ggagtggcgg agccagaagt ggcaactgca ccccctgaaa aggaaatacc ttcattggat     1440

caagagaaaa ccaaacttga gcctggtcaa ccccagctgt ctccaggcat ttccactatt     1500

catctgcatc cacagtttcc agtagtgatt gaaaaaacat cacctcctgt gcctgttgaa     1560

gtagctcctg aagcttctac gtctagtgcc agccaagtga ttgctcctac tcaagtgaca     1620

gaaatcaatg aatgtactgt gaaccctgat atctgtggag caggacactg cattaaccta     1680

ccagtgagat atacctgtat atgctacgag ggctacaggt tcagtgaaca acagaggaaa     1740

tgtgtggata ttgatgagtg tactcaggtc caacacctct gctcccaggg ccgctgtgaa     1800

aacaccgagg gaagtttctt gtgcatttgc ccagcaggat ttatggccag tgaggagggt     1860

actaactgca tagatgttga cgaatgcctg aggccggacg tctgtgggga ggggcactgt     1920

gtcaatactg tgggggcctt ccggtgtgaa tactgtgaca gcgggtaccg catgactcag     1980

agaggccgtt gtgaggatat tgatgaatgt ttgaatccaa gcacttgtcc agatgagcag     2040

tgtgtgaatt ctcctggatc ttaccagtgc gttccctgca cagaaggatt ccgaggctgg     2100

aatggacagt gccttgatgt ggacgagtgc ctggaaccaa acgtctgcgc aaatggtgat     2160

tgttccaacc ttgaaggctc ctacatgtgt tcatgccaca aaggctatac ccggactccg     2220

gaccacaagc actgtagaga tattgatgaa tgtcagcaag ggaatctatg tgtaaacggg     2280

cagtgcaaaa ataccgaggg ctccttcagg tgcacctgtg gacaggggta ccagctgtcg     2340

gcagctaaag accagtgtga agacattgat gaatgccagc accgtcatct ctgtgctcat     2400

gggcagtgca ggaacactga gggctctttt caatgtgtgt gtgaccaggg ttacagagca     2460

tctgggcttg gagaccactg tgaagatatc aatgaatgct tggaggacaa gagtgtttgc     2520

cagagaggag actgcattaa tactgcaggg tcctatgatt gtacttgtcc ggatggattt     2580

cagctagatg acaataaaac atgtcaagat attaatgaat gtgaacatcc agggctctgt     2640

ggtccgcaag gggagtgcct aaacacagag ggttctttcc attgtgtctg ccagcagggt     2700

ttctcaatct ctgcagatgg ccgtacgtgt gaagatgtga atgaatgtga actgctcagt     2760

ggggtgtgtg gtgaagcctt ctgtgaaaac gtggaagggt ccttcctgtg cgtgtgtgct     2820

gatgaaaacc aagagtacag ccccatgact gggcagtgcc gctcccggac ctccacagat     2880

ttagatgtag atgtagatca acccaaagaa gaaaagaaag aatgctacta taatctcaat     2940

gacgccagtc tctgtgataa tgtgttggcc cccaatgtca cgaaacaaga atgctgctgt     3000

acatcaggcg cgggatgggg agataactgc gaaatcttcc cctgcccggt cttgggaact     3060

gctgagttca ctgaaatgtg tcccaaaggg aaaggttttg tgcctgctgg agaatcatct     3120

tctgaagctg gtggtgagaa ctataaagat gcagatgaat gcctactttt tggacaagaa     3180

atctgcaaaa atggtttctg tttgaacact cggcctgggt atgaatgcta ctgtaagcaa     3240

gggacgtact atgatcctgt gaaactgcag tgctttgata tggatgaatg tcaagacccc     3300

agtagttgta ttgatggcca gtgtgttaat acagagggct cttacaactg cttctgtact     3360

caccccatgg tcctggatgc gtcagaaaaa agatgtatac gaccggctga gtcaaacgaa     3420

caaatagaag aaactgatgt ctaccaagat ttgtgctggg aacatctgag tgatgaatac     3480

gtgtgtagcc ggcctcttgt gggcaagcag acaacgtaca ctgagtgctg ctgtctgtat     3540

ggagaggcct ggggcatgca gtgtgccctc tgccccctga aggattcaga tgactatgct     3600

cagctgtgta acatccccgt gacgggacgc cggcagccat atggacggga cgccttggtt     3660

gacttcagtg aacagtatac tccagaagcc gatccctact tcatccaaga ccgttttcta     3720

aatagctttg aggagttaca ggctgaggaa tgcggcatcc tcaatggatg tgaaaatggt     3780

cgctgtgtga gggtccagga aggttacacc tgcgattgct ttgatgggta tcacttggat     3840

acggccaaga tgacctgtgt cgatgtaaat gaatgcgatg agttgaacaa ccggatgtct     3900

ctctgcaaga atgccaagtg cattaacacc gatggttcct acaagtgttt gtgtctgcca     3960

ggctacgtgc cttctgacaa gccaaactac tgcactccgt tgaataccgc cttgaattta     4020

gagaaagaca gtgacctgga gtgaaacaga atctacataa cctaagccca tatactctgc     4080

actgtgtaaa ggaaaaggga gaaatgtatt atacttgaga cattgcacct accccggaag     4140

gctggaaata cagaaacagc atggaattgc aagtcctctg aagacaatga gaggatttag     4200

gatgagcccg ataggtgtgg cagaccaaat ggacatttct ctaaaaaacc agtatatata     4260

gtctgttcat atgtaaaatt caatggaaga gaggtggaac agtgctgtta ttttaaacag     4320

aaggttgtat tattatgttg ttttgttttt ttactattgc ttgattaaat ttggcattta     4380

aatagtggtg gaaatatttt atataatttt cattttttgg ttgtgcagtt ccttggctac     4440

tgtttttctt ttacttcagt tttttaaaaa tctcaaatga aaaagtcttc gatacaatat     4500

tgttaagctg tattataagt attgttacac agggttatgc aattcccggc ctggagcatt     4560

tttgaaattc aaattgtctg tcctgtggag caggcagtga ttttgttcca aaactttgta     4620

tacacatttg gagaaaagta ctttatattt tcagtgtttt gtctgatttt aatgtccgtt     4680

cttagccaag ctgctagcag gtgttaattg gatccctttc cttcactgaa atggaagagt     4740

ttataagctt acgttagtat tgtaatatgt aaagtaagcc caacaaaaat ttttaaaaat     4800

ttgatgatcc ccaatatatc taccattgta tgttaaataa atcaccattt ttgtagaaaa     4860

aattctacct gagagtaatt gtcaatgagt acatgtgtat aagttgtatc ccactctccc     4920

cacttttatc ttttccagtg gtcttctgtt aatgtagtgt cttttacaag ttaatcatta     4980

aatttgttag atcttgttat gggctaaaaa aaaaaaaaaa aaa                       5023


<210>  848
<211>  6168
<212>  DNA
<213>  homo sapiens

<400>  848
ggtcgcgccc gctggggccc gcgatggcgg gggcctggct caggtggggg ctcctgctct       60

gggcagggct cctcgcgtcc tcggcgcacg gccggctgcg gaggatcacc tacgtggtgc      120

acccgggccc cggcctggca gccggcgcct tgcccctgag cgggcccccg cgttcgcgga      180

cattcaacgt cgcgctcaac gccaggtaca gccgcagctc ggcggctgcc ggcgccccca      240

gccgtgcctc ccccggggtc ccctcggaga ggacccggcg cacgagcaag ccgggcggcg      300

cggccctgca ggggctcaga ccgccgccgc cgccgccgcc ggagcctgcg cgtcccgcgg      360

tccccggcgg gcagctccac cccaatcccg gcggccaccc ggcagccgcc ccgttcacca      420

aacaaggcag gcaagttgtg cgctccaagg tgccgcagga gacccagagc ggcggaggct      480

ctaggctgca ggttcaccag aagcagcagc tgcagggggt caatgtctgt ggagggcggt      540

gctgtcatgg ctggagtaag gcccctggct cccagaggtg caccaaacct agctgtgttc      600

cgccatgtca gaatggaggg atgtgtctcc ggccacaact ctgtgtgtgt aaaccaggga      660

ccaagggcaa agcctgtgaa acaatagctg cccaggacac ctcgtcacca gtctttggag      720

ggcagagtcc tggggctgct tcctcgtggg gccctcctga gcaagcagca aagcatactt      780

catctaagaa ggcagacact ctaccaagag tcagccctgt ggcccagatg accttaaccc      840

tcaagccgaa gccttcagtg ggactccccc agcagataca ttctcaagtg actcctcttt      900

cttcccagag tgtggtgatt caccatggcc agacccagga atacgtgctc aagcccaagt      960

actttccagc ccagaagggg atttcaggag agcagtccac tgaaggttct ttccctttaa     1020

gatatgtgca ggatcaagtt gcggcacctt ttcagctgag taaccacact ggccgcatca     1080

aggtggtctt tactccgagc atctgtaaag tgacctgcac caagggcagc tgtcagaaca     1140

gctgtgagaa ggggaacacc accactctca ttagtgagaa tggtcatgct gccgacaccc     1200

tgacggccac gaacttccga gtggtaattt gccatcttcc atgtatgaat ggtggccagt     1260

gcagttcaag ggacaaatgt cagtgccctc caaatttcac aggaaaactt tgtcagatcc     1320

cagtccatgg tgccagcgtg cctaaacttt atcagcattc ccagcagcca ggcaaggcgt     1380

tggggacgca tgtcatccat tcaacacata ccttgcctct gaccgtgact agccagcaag     1440

gagtcaaagt gaaatttcct cctaacatag tcaatatcca tgtgaaacat cctcctgaag     1500

cttccgtcca gatacatcag gtttcaagaa ttgatggccc aacaggccag aagacaaaag     1560

aagctcaacc aggccaatcc caagtctcgt accaagggct tcctgtccag aagacccaga     1620

ccatacattc cacatactcc caccagcagg tcattcctca cgtctacccc gtggctgcta     1680

agacacagct tggccggtgc ttccaggaaa ccattgggtc acagtgtggc aaagcgctcc     1740

ctggcctttc aaagcaagag gactgctgtg gaactgtggg tacctcctgg ggctttaaca     1800

aatgccagaa atgccccaag aaaccatctt atcatggata caaccaaatg atggaatgcc     1860

taccgggtta taagcgggtt aacaacacct tttgccaaga tattaatgaa tgtcagctac     1920

aaggtgtatg ccctaatggt gagtgtttga ataccatggg cagctatcga tgtacctgca     1980

aaataggatt tgggccggat cctacctttt caagttgtgt tcctgatccc cctgtgatct     2040

cggaagagaa agggccctgt taccgacttg tcagttctgg aagacagtgt atgcaccctc     2100

tgtctgttca cctcaccaag cagctctgct gttgtagtgt gggcaaggcc tggggcccac     2160

actgtgagaa atgtcccctt ccaggcacag ctgcttttaa ggaaatctgt cctggtggaa     2220

tgggttatac ggtttctggc gttcatagac gcaggccaat ccatcaccat gtaggtaaag     2280

gacctgtatt tgtcaagcca aagaacactc aacctgttgc taaaagtact catcctccac     2340

ctctcccagc caaggaagag ccagtggagg ccctgacctt ctcccgggaa cacgggccag     2400

gagtggcgga gccagaagtg gcaactgcac cccctgaaaa ggaaatacct tcattggatc     2460

aagagaaaac caaacttgag cctggtcaac cccagctgtc tccaggcatt tccactattc     2520

atctgcatcc acagtttcca gtagtgattg aaaaaacatc acctcctgtg cctgttgaag     2580

tagctcctga agcttctacg tctagtgcca gccaagtgat tgctcctact caagtgacag     2640

aaatcaatga atgtactgtg aaccctgata tctgtggagc aggacactgc attaacctac     2700

cagtgagata tacctgtata tgctacgagg gctacaggtt cagtgaacaa cagaggaaat     2760

gtgtggatat tgatgagtgt actcaggtcc aacacctctg ctcccagggc cgctgtgaaa     2820

acaccgaggg aagtttcttg tgcatttgcc cagcaggatt tatggccagt gaggagggta     2880

ctaactgcat agatgttgac gaatgcctga ggccggacgt ctgtggggag gggcactgtg     2940

tcaatactgt gggggccttc cggtgtgaat actgtgacag cgggtaccgc atgactcaga     3000

gaggccgttg tgaggatatt gatgaatgtt tgaatccaag cacttgtcca gatgagcagt     3060

gtgtgaattc tcctggatct taccagtgcg ttccctgcac agaaggattc cgaggctgga     3120

atggacagtg ccttgatgtg gacgagtgcc tggaaccaaa cgtctgcgca aatggtgatt     3180

gttccaacct tgaaggctcc tacatgtgtt catgccacaa aggctatacc cggactccgg     3240

accacaagca ctgtagagat attgatgaat gtcagcaagg gaatctatgt gtaaacgggc     3300

agtgcaaaaa taccgagggc tccttcaggt gcacctgtgg acaggggtac cagctgtcgg     3360

cagctaaaga ccagtgtgaa gacattgatg aatgccagca ccgtcatctc tgtgctcatg     3420

ggcagtgcag gaacactgag ggctcttttc aatgtgtgtg tgaccagggt tacagagcat     3480

ctgggcttgg agaccactgt gaagatatca atgaatgctt ggaggacaag agtgtttgcc     3540

agagaggaga ctgcattaat actgcagggt cctatgattg tacttgtccg gatggatttc     3600

agctagatga caataaaaca tgtcaagata ttaatgaatg tgaacatcca gggctctgtg     3660

gtccgcaagg ggagtgccta aacacagagg gttctttcca ttgtgtctgc cagcagggtt     3720

tctcaatctc tgcagatggc cgtacgtgtg aagatattga tgaatgtgta aacaacactg     3780

tttgtgacag tcacgggttt tgtgacaata cagctggctc cttccgctgc ctctgttatc     3840

agggctttca agccccacag gatgggcaag ggtgtgtgga tgtgaatgaa tgtgaactgc     3900

tcagtggggt gtgtggtgaa gccttctgtg aaaacgtgga agggtccttc ctgtgcgtgt     3960

gtgctgatga aaaccaagag tacagcccca tgactgggca gtgccgctcc cggacctcca     4020

cagatttaga tgtagatgta gatcaaccca aagaagaaaa gaaagaatgc tactataatc     4080

tcaatgacgc cagtctctgt gataatgtgt tggcccccaa tgtcacgaaa caagaatgct     4140

gctgtacatc aggcgcggga tggggagata actgcgaaat cttcccctgc ccggtcttgg     4200

gaactgctga gttcactgaa atgtgtccca aagggaaagg ttttgtgcct gctggagaat     4260

catcttctga agctggtggt gagaactata aagatgcaga tgaatgccta ctttttggac     4320

aagaaatctg caaaaatggt ttctgtttga acactcggcc tgggtatgaa tgctactgta     4380

agcaagggac gtactatgat cctgtgaaac tgcagtgctt tgatatggat gaatgtcaag     4440

accccagtag ttgtattgat ggccagtgtg ttaatacaga gggctcttac aactgcttct     4500

gtactcaccc catggtcctg gatgcgtcag aaaaaagatg tatacgaccg gctgagtcaa     4560

acgaacaaat agaagaaact gatgtctacc aagatttgtg ctgggaacat ctgagtgatg     4620

aatacgtgtg tagccggcct cttgtgggca agcagacaac gtacactgag tgctgctgtc     4680

tgtatggaga ggcctggggc atgcagtgtg ccctctgccc cctgaaggat tcagatgact     4740

atgctcagct gtgtaacatc cccgtgacgg gacgccggca gccatatgga cgggacgcct     4800

tggttgactt cagtgaacag tatactccag aagccgatcc ctacttcatc caagaccgtt     4860

ttctaaatag ctttgaggag ttacaggctg aggaatgcgg catcctcaat ggatgtgaaa     4920

atggtcgctg tgtgagggtc caggaaggtt acacctgcga ttgctttgat gggtatcact     4980

tggatacggc caagatgacc tgtgtcgatg taaatgaatg cgatgagttg aacaaccgga     5040

tgtctctctg caagaatgcc aagtgcatta acaccgatgg ttcctacaag tgtttgtgtc     5100

tgccaggcta cgtgccttct gacaagccaa actactgcac tccgttgaat accgccttga     5160

atttagagaa agacagtgac ctggagtgaa acagaatcta cataacctaa gcccatatac     5220

tctgcactgt gtaaaggaaa agggagaaat gtattatact tgagacattg cacctacccc     5280

ggaaggctgg aaatacagaa acagcatgga attgcaagtc ctctgaagac aatgagagga     5340

tttaggatga gcccgatagg tgtggcagac caaatggaca tttctctaaa aaaccagtat     5400

atatagtctg ttcatatgta aaattcaatg gaagagaggt ggaacagtgc tgttatttta     5460

aacagaaggt tgtattatta tgttgttttg tttttttact attgcttgat taaatttggc     5520

atttaaatag tggtggaaat attttatata attttcattt tttggttgtg cagttccttg     5580

gctactgttt ttcttttact tcagtttttt aaaaatctca aatgaaaaag tcttcgatac     5640

aatattgtta agctgtatta taagtattgt tacacagggt tatgcaattc ccggcctgga     5700

gcatttttga aattcaaatt gtctgtcctg tggagcaggc agtgattttg ttccaaaact     5760

ttgtatacac atttggagaa aagtacttta tattttcagt gttttgtctg attttaatgt     5820

ccgttcttag ccaagctgct agcaggtgtt aattggatcc ctttccttca ctgaaatgga     5880

agagtttata agcttacgtt agtattgtaa tatgtaaagt aagcccaaca aaaattttta     5940

aaaatttgat gatccccaat atatctacca ttgtatgtta aataaatcac catttttgta     6000

gaaaaaattc tacctgagag taattgtcaa tgagtacatg tgtataagtt gtatcccact     6060

ctccccactt ttatcttttc cagtggtctt ctgttaatgt agtgtctttt acaagttaat     6120

cattaaattt gttagatctt gttatgggct aaaaaaaaaa aaaaaaaa                  6168


<210>  849
<211>  5311
<212>  DNA
<213>  homo sapiens

<400>  849
agcgcgagtg acggcgcgcc ctccgggctc cggagcggcg gcgccgaaca atccccggca       60

gggctcgcct cgccggtgac atcactcctg aagatactcc tcgctcccag cgcctgcctt      120

ccccaggcgt ccgttcgtgt gcccgtctcc gcctttccgc ctcggaagag cgctcatcac      180

tggctgggga cagagccggg caccaaggag cgacaggatc ccgaagagag agagagaagg      240

cagcgaggga aggaggaccc cggcaggcag cagcatgaaa ttcagcccag cgcactacct      300

gctgcctctc ctgcctgcgc tggtcctcag caccagacag gactatgaag agctagaaaa      360

gcagctgaaa gaagtcttta aggagcgaag caccattctt cgtcagctga caaagacatc      420

aagagaactt gatggaatta aagtcaatct tcagtcctta aaaaacgatg agcagtctgc      480

caaaactgat gttcagaaac ttctggaatt aggacagaaa caaagagaag aaatgaagtc      540

tcttcaggag gccctgcaaa atcagcttaa ggagacatca gagaaagcag aaaaacacca      600

ggctactatt aattttttaa agactgaagt tgaaagaaag agcaaaatga tccgagacct      660

ccagaatgag aataaaagct tgaaaaacaa actcttgtca ggaaacaagc tctgtggcat      720

tcacgcagaa gagtcaaaaa aaatccaagc ccagctgaag gagcttcgtt atgggaagaa      780

ggatttatta tttaaggcgc agcagcttac tgatctggaa caaaaattag ctgtagccaa      840

aaatgaactg gagaaagcag ctcttgacag ggagtcacag atgaaagcaa tgaaagagac      900

tgtgcagctc tgcttgacat ctgttttccg tgatcagcct cctccccctt tgagtttaat      960

cacatcaaat ccaactcgga tgttactccc acccaggaat attgcctcta agcttccaga     1020

tgcagcggcc aaaagcaagc ctcaacaaag tgcttctgga aacaatgaga gctctcaagt     1080

tgagtcaaca aaggaaggaa atccaagtac cactgcctgt gactctcaag atgagggcag     1140

accgtgttcc atgaagcaca aagaaagtcc cccaagtaat gccactgcag aaaccgagcc     1200

tatcccacag aaattgcaaa tgcctccttg ctctgaatgt gaggtgaaaa aagccccaga     1260

aaaaccattg accagctttg aagggatggc agctagagaa gaaaaaatac tgtaaatact     1320

aagaaactgt gttaaaaacg tccatttgct attgtcttca tattcttttt agaccacaag     1380

cttgatggaa atactgtttc taaagcatgc aactttttca caattttatg taactttata     1440

aagtagccta cacattttca aagattccag accaattatg atccttaagc aataacctca     1500

ttgaattgaa tacccacagt cagaaatatt ttgttgtcaa cagtaaattg tcccatataa     1560

attggtctgg tttaactcaa atgctatcta acatgtaatt ctcccggttc atttggatat     1620

ctagtacttc tatgatatag ttgtcaaaat caactggagg ataataaaat attgtgggtt     1680

ctcagcattc ttagaatcca aattacaacc atatcagtaa gggtttggtc cacatgagcc     1740

aactgaagtc attttcctca aggttggaat ttgtgccaac ctaaatacgt tgtttctttg     1800

atggtgttta ttgctattgg tattattttg aactaataac aattattttg tctaaataat     1860

gctaagacaa ttctgttaag aattttgtca gctaacataa ttcattaagt atgtttggca     1920

tcatatggac aaaatatttg gatgaatgac taaatttctg acacaattaa atattttggc     1980

attctataga cacatctcct atgtatgtct actgtaatta atccaagtta ataaccaagt     2040

tttctgaaat acttggcagg atttttggta tgaagttggg tagtggaata gggaatgaag     2100

agtgagttct aaaatacaaa tatgaaagca ggtaatatat atcacaaaac aggggtctga     2160

tgaaagtaca atagccatgt tgattcaata aacccagatg catatttttt gaaaaccaat     2220

gtgttattga aacaaatcaa tggcagtgtt aatccataag agttctgatt ttctatagga     2280

atatcactaa tcaaaaaaat gcactcatga ataattggaa gatagctcac aagcaagagg     2340

aattgaccct tgaataatta tctgattaat aggtttcata gggcattcaa agttgcagac     2400

tcagttaatg actacagtta agttgtctgg actgaaaagt catttctttt gtttagaacc     2460

tttttgcaac cgtagaaagc atattaaacc attggttttg caggatggat ctgtcaaacc     2520

acaatatata catttggatc agtgtatcct aggagacagt taataaaaat gtattaaagg     2580

aaatctttaa tcaataaatg aacttagatt ctgagattta atggcatacc tctgatcaaa     2640

atggcatatt taaagaaatt taaagatttg gagaattgga aaatatcgtt agctgtaaaa     2700

gtaatattat gacatattta tgtagcactt ctattttcag aatagttcag tgtcattcat     2760

tagcacaggc aggtcccaac cacaatggtt caacttaacg gttttttcat gattctgtga     2820

aagcttcata atttctacat gctttgaatt ttgaattttg ttattttttg gagggctagt     2880

gatacatggt ccatgaaata ttcaacactt tattataaaa tagggtttgt gttagacaat     2940

ttgcccaact gtaggatgag gtatatgttc tgagcacgtt taagcaggtt taagttaggg     3000

tgggctatga ttttccattt aggtatctga aatgcatttc agacttacaa tgttttcaac     3060

ctttgacttc tttatctgta tgtaatccta ttgttaaatc aaggagcatt catatttttc     3120

ataaaaccgg ctacccaagg aaaaaaataa ttagctttat ggatgatcca tagagctttc     3180

agatgaagtg actaggataa aataaaagat gaaggtctga ggtttcttct gactccttca     3240

tatttctaaa aataatcata caaactagaa tactgctagt ctcccaagtc ctgttccttg     3300

taattctccc actgttctca gtggccctaa ccatctctat aggttcctga cagggaagca     3360

gatcatttag ttttaattta tgttcagtct cccacctcca ccctggggcc caacttccct     3420

tgcaggcctt gtgggtccta tagaaagtta ttcaccatgt aatctagcac agcatgtttt     3480

gaagcatctt tggaatgaaa aaaaagaaga atcaggctgt tatttcctga aattgttatg     3540

agagataaca tgttgaaagg taagaactca ggttgatatt aatcatgttt ttatcaatct     3600

tcattttaaa gttgtttttg ttctgtatat tctaaattcc ttttattaat tcctggcttg     3660

atcaagtggg ctttggatcc atatgatttt tttttttttt tttttttgag atgaaatctc     3720

gctcttgttg cccaggctgg agtgcaatgg agcgatcttg gctcactgca actctgcttc     3780

ccaggttcaa gtgattctcc ctgcctccgc ctcccaagta gctgggatta caggtacctg     3840

ccaccatgcc cggctaattt ttatattttt aatagagacg gggtttcacc atgttggcca     3900

ggctggtctc gaactcctga cctcaggcga tccacctgcc tcagtctcct cccaaaatgc     3960

tgggattaca ggtgtgagcc accgtgcctg gccagtgtgt ttttttcctt taaatatata     4020

tggcattata catccagcaa agtttactgt gttatactca ttgcatcatt tgtttaaaaa     4080

aaaaaaagaa acttgtagca ggagacattt aaaaatatat ttaggagttc cttttaataa     4140

ctaagttaga gactctcttt cagtaagttc tatgactgta ccttaatgaa tgcattttat     4200

ttatctcaat ttttatttgc ttcaaaatag aatcggataa gtttaaaatg ttcctcttac     4260

atttgtgaat gtgtctatga gagaggggcc atttctcaca tattttaatt aacaactaaa     4320

taaacagacg ttgttttaaa ggaattaaca cttaaatccc aaccatcctc atatagaata     4380

aaatatcaac ctaaatcttt actatagata gtataattct attatgtacc tgtaatgata     4440

agcattgaaa gattatttac attttgaaaa acatggaatt gattcttatt aagaaaaaag     4500

atattttcca atggagtaac ttgttttaat agaggtacaa ccagaaccaa caattgtatt     4560

tctctatagt tattttaaaa tagtaatcaa tgctatgtat ttgatgtata tgtttctaaa     4620

ttagaaattt cttttggctt tgtgtttttt taatgtgcgt taaatatgta aactgaacct     4680

gttcctaaaa tgcattaaac ttgaatgctg tgtctatcca atgccaaaat gctcagaaga     4740

aaagtgaata attcagtcat tcatctggat gtagttttct gtgtaatctc aaatatctga     4800

atattgaaaa aactaggttg ctaacttttt tcattcctta tgcaaatgtt tagcatcata     4860

gtgctgtttc agatacagat ctgtttcatc aaatatcctc aattacaagt ctaagacagt     4920

tatatgtaaa gaaaatgtat tattttagat gaacaatgtg gataactgaa ctaaaacgat     4980

atttgtgaac tttgctataa tgaaatcttt tatttttata gctcaggtat tgtaattagc     5040

actaattgca gcagagactg aaataattat tgacaccgta gagtaccata gagtaggttg     5100

aactggccag acctagacaa tgaagaaaac acatactgtt tacttaggag acattttctt     5160

agtcgtgtgt atagtcctaa atttccccaa actatgtgtt catttggatt gtgttatata     5220

ataacagtcg aatgatgaag aataaaagat gctgaaagat ggcctatttt tgttcaataa     5280

agattgttac aagaataaaa aaaaaaaaaa a                                    5311


<210>  850
<211>  2683
<212>  DNA
<213>  homo sapiens

<400>  850
agggcggtgt caatgcaccc tccagcggtg cgcgcaggcg ggagaaggga gggcggcccg       60

ggcaagtgag acagttaagg cagtgtcccc accacacccc cacccagatt ggccacgccg      120

agctggttct tgacagaagg ccttcgcgga ggaagagggg gcacagctgc acaggacacc      180

ctacggagcc tgcgggcgtg gaactttgcc aggcgcacgg gaacgcgcgc ccttcctgtc      240

agcctcccgg ggcgccaggc tcccgcggcc cgcagcggga cagcctcagt tgtgtgggct      300

ggacccagtc gctggggtac cgaccagtcc tggaaggcgc agaggacgtg gagtggggag      360

gctgccttcc tatgtgcgaa gggccagccg ggcacgcagt cctcagaccc tagtccgcac      420

ccggcaggtc cccacggcac ctgctgcgcc ctcctcgccg ctcccccaac ctccccatct      480

cagaaaacta ccagttctct cccgcccccc ggcgcccctt tcccaggaac gtgcggaggc      540

gggagaagag gaagacagga agggggtggg gatgtgaagc gaccgtccca gccttccccg      600

cccgccaccc ccaccccaac tcggcagccg tcacgtgatg cctggagtgg gaggtgggga      660

gaaaaggcga gacttttgtg ggtgctcccg atcgccagta gttccttcag tctcagccgc      720

caactccgga ggcgcggtgc tcggcccggg agcgcgagcg ggaggagcag agacccgcag      780

ccgggagccc gagcgcgggc gatgcaggct ccgcgagcgg cacctgcggc tcctctaagc      840

tacgaccgtc gtctccgcgg cagcagcgcg ggccccagca gcctcggcag ccacagccgc      900

tgcagccggg gcagcctccg ctgctgtcgc ctcctctgat gcgcttgccc tctcccggcc      960

ccgggactcc gggagaatgt gggtcctagg catcgcggca actttttgcg gattgttctt     1020

gcttccaggc tttgcgctgc aaatccagtg ctaccagtgt gaagaattcc agctgaacaa     1080

cgactgctcc tcccccgagt tcattgtgaa ttgcacggtg aacgttcaag acatgtgtca     1140

gaaagaagtg atggagcaaa gtgccgggat catgtaccgc aagtcctgtg catcatcagc     1200

ggcctgtctc atcgcctctg ccgggtacca gtccttctgc tccccaggga aactgaactc     1260

agtttgcatc agctgctgca acacccctct ttgtaacggg ccaaggccca agaaaagggg     1320

aagttctgcc tcggccctca ggccagggct ccgcaccacc atcctgttcc tcaaattagc     1380

cctcttctcg gcacactgct gaagctgaag gagatgccac cccctcctgc attgttcttc     1440

cagccctcgc ccccaacccc ccacctccct gagtgagttt cttctgggtg tccttttatt     1500

ctgggtaggg agcgggagtc cgtgttctct tttgttcctg tgcaaataat gaaagagctc     1560

ggtaaagcat tctgaataaa ttcagcctga ctgaattttc agtatgtact tgaaggaagg     1620

aggtggagtg aaagttcacc cccatgtctg tgtaaccgga gtcaaggcca ggctggcaga     1680

gtcagtcctt agaagtcact gaggtgggca tctgcctttt gtaaagcctc cagtgtccat     1740

tccatccctg atgggggcat agtttgagac tgcagagtga gagtgacgtt ttcttagggc     1800

tggagggcca gttcccactc aaggctccct cgcttgacat tcaaacttca tgctcctgaa     1860

aaccattctc tgcagcagaa ttggctggtt tcgcgcctga gttgggctct agtgactcga     1920

gactcaatga ctgggactta gactggggct cggcctcgct ctgaaaagtg cttaagaaaa     1980

tcttctcagt tctccttgca gaggactggc gccgggacgc gaagagcaac gggcgctgca     2040

caaagcgggc gctgtcggtg gtggagtgcg catgtacgcg caggcgcttc tcgtggttgg     2100

cgtgctgcag cgacaggcgg cagcacagca cctgcacgaa cacccgccga aactgctgcg     2160

aggacaccgt gtacaggagc gggttgatga ccgagctgag gtagaaaaac gtctccgaga     2220

aggggaggag gatcatgtac gcccggaagt aggacctcgt ccagtcgtgc ttgggtttgg     2280

ccgcagccat gatcctccga atctggttgg gcatccagca tacggccaat gtcacaacaa     2340

tcagccctgg gcagacacga gcaggaggga gagacagaga aaagaaaaac acagcatgag     2400

aacacagtaa atgaataaaa ccataaaata tttagcccct ctgttctgtg cttactggcc     2460

aggaaatggt accaattttt cagtgttgga cttgacagct tcttttgcca caagcaagag     2520

agaatttaac actgtttcaa acccggggga gttggctgtg ttaaagaaag accattaaat     2580

gctttagaca gtgtatttat accagttgat gtctgttaat tttaaaaaaa tgttttcatt     2640

ggtgtttgtt tgcgtatcca gaaagcagtt catgttatcc ata                       2683


<210>  851
<211>  2400
<212>  DNA
<213>  homo sapiens

<400>  851
ggcctgcagg gagcagccgc gagccggccg ggcgcgccga gcccgagccc cagccggagc       60

ggggcggggg agggaggagc cagagcggcc gccgcctctg ccggaggagc cgcggggccg      120

ccacactcgc cccccgcccc ccccgcgctc actcgcactc acacccgggc gcaggaggcg      180

ggcggcccgg gccccaccgg ccccccatgg acgcccccag cacggggcgc tgagaccccc      240

gcgtcgctgc ccagcccggt ccggcgcgcc acgccgaggg atctctggac aggacaagac      300

tccgaagcta ctcccccagc acacagcccg ggacccacaa acccagcttg cccccagccc      360

tcccacctgc cactccctgg cccctcccac cgcccgcccc ccttggggcg cagggcatgg      420

tgtgaaaggc caagtgctga ggcgggtatc atgggtgctg tgccctaggg cctgggtggc      480

agggggtggg tggcctgtgg gtgtgccggg ggggccagtg tgcccacccc agtctcttgg      540

cgtgctggag ggcatcctgg atggaattga agtgaatgga acagaagcca agcaaggtgg      600

agtgtgggtc agacccagag gagaacagtg ccaggtcacc agatggaaag cgaaaaagaa      660

agaacggcca atgttccctg aaaaccagca tgtcagggta tatccctagt tacctggaca      720

aagacgagca gtgtgtcgtg tgtggggaca aggcaactgg ttatcactac cgctgtatca      780

cttgtgaggg ctgcaagggc ttctttcgcc gcacaatcca gaagaacctc catcccacct      840

attcctgcaa atatgacagc tgctgtgtca ttgacaagat cacccgcaat cagtgccagc      900

tgtgccgctt caagaagtgc atcgccgtgg gcatggccat ggacttggtt ctagatgact      960

cgaagcgggt ggccaagcgt aagctgattg agcagaaccg ggagcggcgg cggaaggagg     1020

agatgatccg atcactgcag cagcgaccag agcccactcc tgaagagtgg gatctgatcc     1080

acattgccac agaggcccat cgcagcacca atgcccaggg cagccattgg aaacagaggc     1140

ggaaattcct gcccgatgac attggccagt cacccattgt ctccatgccg gacggagaca     1200

aggtggacct ggaagccttc agcgagttta ccaagatcat caccccggcc atcacccgtg     1260

tggtggactt tgccaaaaaa ctgcccatgt tctccgagct gccttgcgaa gaccagatca     1320

tcctcctgaa ggggtgctgc atggagatca tgtccctgcg ggcggctgtc cgctacgacc     1380

ctgagagcga caccctgacg ctgagtgggg agatggctgt caagcgggag cagctcaaga     1440

atggcggcct gggcgtagtc tccgacgcca tctttgaact gggcaagtca ctctctgcct     1500

ttaacctgga tgacacggaa gtggctctgc tgcaggctgt gctgctaatg tcaacagacc     1560

gctcgggcct gctgtgtgtg gacaagatcg agaagagtca ggaggcgtac ctgctggcgt     1620

tcgagcacta cgtcaaccac cgcaaacaca acattccgca cttctggccc aagctgctga     1680

tgaaggtgac tgacctccgc atgatcgggg cctgccacgc cagccgcttc ctccacatga     1740

aagtcgagtg ccccaccgaa ctcttccccc cactcttcct cgaggtcttt gaggatcagg     1800

aagtctaaag cctcaggcgg ccagagggtg tgcggagctg gtggggagga gcctggagag     1860

aaggggcaga gctgggggct gagggagacc cccccacacc ccttctctcc ttcctctcgt     1920

ccttggatag attcagctcc cacacacaca cccgcactgc ccaggtccct cctcagacct     1980

ccagccctgg gacagggcaa acaactgaac ttgctatgga aaggacagtg tgggaggctg     2040

ggggagctgt gtcctgcagt tcccaggacc ccatcctctc agaaggtagg ggaagggcgg     2100

gaggattgag aagggacaag ccaccttgac cgtaggggaa ggaggaatgt gggctggggg     2160

aagatgccct caactcaccc cctacacaca catgagagag agcccccacc cagttccttg     2220

gcctaggtct cccctccagg ctgagggcct ctctacttcc ccagatgcct gggtgcaaag     2280

aacggcttgg cttggctcct cctctggagg ttaaaattta tagtcattct aactgcactt     2340

tggaaaccaa gcaaggggag aagacaaatg aagaaaaact agacagagaa aaaaaaaaaa     2400


<210>  852
<211>  2577
<212>  DNA
<213>  homo sapiens

<400>  852
ccttttctcg gggcgcccga gaggccagct cagacctccc ggctcgacag gcggcgcggg       60

cggcggtaaa atgtcggttc caggacctta ccaggcggcc actgggcctt cctcagcacc      120

atccgcacct ccatcctatg aagagacagt ggctgttaac agttattacc ccacacctcc      180

agctcccatg cctgggccaa ctacggggct tgtgacgggg cctgatggga agggcatgaa      240

tcctccttcg tattataccc agccagcgcc catccccaat aacaatccaa ttaccgtgca      300

gacggtctac gtgcagcacc ccatcacctt tttggaccgc cctatccaaa tgtgttgtcc      360

ttcctgcaac aagatgatcg tgagtcagct gtcctataac gccggtgctc tgacctggct      420

gtcctgcggg agcctgtgcc tgctggggca ggagtgcagt ggtacgatcg tagctctccg      480

cagctttgat ctcctgggct cctgcaatcc gcccagctca gcctcctgag tacctgggac      540

cacaggtgca tagcgggctg ctgcttcatc cccttctgcg tggatgccct gcaggacgtg      600

gaccattact gtcccaactg cagagctctc ctgggcacct acaagcgttt gtaggactca      660

gccagacgtg gagggagccg ggtgccgcag gaagtccttt ccacctctca tccagcttca      720

cgcctggtgg aggttctgcc ctggtggtct cacctctcca gggggcccac cttcatgtct      780

tcttttgggg ggaatacgtc gcaaaactaa caaatctcca aaccccagaa attgctgctt      840

ggagtcgtgc ataggacttg caaagacatt ccccttgagt gtcagttcca cggtttcctg      900

cctccctgag accctgagtc ctgccatcta actgtgatca ttgccctatc cgaatatctt      960

cctgtgatct gccatcagtg gctctttttt cctgcttcca tgggcctttc tggtggcagt     1020

ctcaaactga gaagccacag ttgccttatt tttgaggctg ttctgcccag agctcggctg     1080

aaccagcctt tagtgcctac cattatctta tccgtctctt cccgtccctg atgacaaaga     1140

tcttgcctta cagactttac aggcttggct ttgagattct gtaactgcag acttcattag     1200

cacacagatt cactttaatt tcttaatttt ttttttaaat acaaggaggg ggctattaac     1260

acccagtaca gacatatcca caaggtcgta aatgcatgct agaaaaatag ggctggatct     1320

tatcactgcc ctgtctcccc ttgtttctct gtgccagatc ttcagtgccc ctttccatac     1380

agggattttt ttctcataga gtaattatat gaacagtttt tatgacctcc ttttggtctg     1440

aaatactttt gaacagaatt tctttttttt aaaaaaaaac agagatgggg tcttactatg     1500

ttgcccaggc tggtgtcgaa ctcctgggct caagcgatcc ttctgccttg gcctcccgaa     1560

gtgctgggat tgcaggcata agctaccatg ctgggcctga acataatttc aagaggagga     1620

tttataaaac cattttctgt aatcaaatga ttggtgtcat tttcccattt gccaatgtag     1680

tctcacttaa aaaaaaaaaa aagaaaaaga aatggataat ttcatctact gcctttactt     1740

ggggttaatg tgattcttaa acaccttcat catggaactc tcagagtggg gtccgttttg     1800

gtttcctggt ggtgggtttt gaaagataag ggaaagcaca ttttgagcat gtctgggtac     1860

catggtgcgg atgcttggga accagaactg tttcagagga atctaaagtc tgattttagt     1920

tttcagagac acagcttgtt gtaaaacatg agaagacatg atttctagga ctcaagcagc     1980

aagccaggat tctaggttgg ctgctgtgtc atctttgaag tcaagacaaa gctgggctcg     2040

accttcaagg gtcctcgttt tgataatact tcagaatagg gaactcatgt gaatactact     2100

atgtagaaat aaaacctaga ccttgagcga acatctgtat attggttgaa aacgatagtg     2160

gtaaccattg atcccccttc atttgatgtt tggaaaattc cagtaattat catttttgca     2220

acgaatatgg ataccacata gtactttggt gttacctgct tttgaaaaat aaagtctttg     2280

gttcacccgg tgaactattt atgagttctt ttggtgtgaa gaaagggctc atgttgcatt     2340

tccagccatt gctacaaaga acctttattt gttcagtaac ggtagaaaat ccttcccgat     2400

taaaaacttc agacttgctg aatatcctgc aatgtcaaga tgaccgatgt tgagttgggt     2460

ggatttgcta acgagtcaga tttgaacatg aggctattgg aacccaatag gcgtcattga     2520

tggcggcaag ccatagcttt caagttttaa taaaatgcac aaaagagaaa aaaaaaa        2577


<210>  853
<211>  1498
<212>  DNA
<213>  homo sapiens

<400>  853
gaaactccaa acaagtttga gatcagcgtt ggctgggggg aggcagtggg ggtgcatcta       60

cgggagcggt tgggctgtaa gctttcgcta catcacagaa ttgtgccagt gtttctcttt      120

ggagtgcctc gccagcttta acaaccgttt ggatatgact tgctcgggca aaagttgtgc      180

attggcccga tcaagcctga cttctagcca aggtattgtt gcagcatctg gcagtgagac      240

tgaggatgag gacagcatgg acattccctt ggacctttct tcatccgctg gctcaggcaa      300

gagaaggaga aggggcaacc tacccaagga gtctgtgcag attcttcggg attggctgta      360

tgagcaccgt tacaatgcct atccttcaga gcaagaaaaa gcgttgctgt cccagcaaac      420

acacctgtct acgctacagg tctgtaactg gttcatcaac gcccgccgca ggctcctccc      480

tgacatgctg agaaaggatg gcaaagatcc aaatcagttc acaatttccc gccgtggggc      540

caagatttct gaaacgagct ctgtggagtc cgtgatgggc atcaaaaact tcatgccagc      600

tctagaggag accccatttc attcctgtac agctgggcca aacccaaccc tagggaggcc      660

actgtctcct aagccgtcat ccccgggatc agttttggct cgtccatcag tgatctgcca      720

taccactgtg actgcattga aagatgtccc tttctctctc tgccagtcgg tcggtgtggg      780

acaaaacaca gatatacagc agatagcggc caaaaacttc acagacacct ctctcatgta      840

cccagaggac acttgtaaat ctggaccaag tacgaataca cagagtggtc ttttcaacac      900

tcctccccct actccaccgg acctcaacca ggacttcagt ggatttcagc ttctagtgga      960

tgttgcactc aaacgggctg cagagatgga gcttcaggca aaacttacag cttaacccat     1020

tttcaagcaa aacagttctc agaaatgtca tgattgccgg ggtgaaggca agagatgaat     1080

tgcattattt tatatatttt ttattaatat ttgcacatgg gattgctaaa acagcttcct     1140

gttactgaga tgtcttcaat ggaatacagt cattccaaga actataaact taaagctact     1200

gtagaaacaa agggttttct tttttaaatg tttcttggta gattattcat aatgtgagat     1260

ggttcccaat atcatgtgat tttttttttc ctccccttcc ctttttttgt tattttttca     1320

gactgtgcaa tacttagaga acctatagca tcttctcatt cccatgtgga acaggatgcc     1380

cacatactgt ctaattaata aattttccat tttttttcaa acaagtatga atctagttgg     1440

ttgatgcctt ttttttcatg acataataaa gtattttctt taaaaaaaaa aaaaaaaa       1498


<210>  854
<211>  2479
<212>  DNA
<213>  homo sapiens

<400>  854
ccttttctcg gggcgcccga gaggccagct cagacctccc ggctcgacag gcggcgcggg       60

cggcggtaaa atgtcggttc caggacctta ccaggcggcc actgggcctt cctcagcacc      120

atccgcacct ccatcctatg aagagacagt ggctgttaac agttattacc ccacacctcc      180

agctcccatg cctgggccaa ctacggggct tgtgacgggg cctgatggga agggcatgaa      240

tcctccttcg tattataccc agccagcgcc catccccaat aacaatccaa ttaccgtgca      300

gacggtctac gtgcagcacc ccatcacctt tttggaccgc cctatccaaa tgtgttgtcc      360

ttcctgcaac aagatgatcg tgagtcagct gtcctataac gccggtgctc tgacctggct      420

gtcctgcggg agcctgtgcc tgctggggtg catagcgggc tgctgcttca tccccttctg      480

cgtggatgcc ctgcaggacg tggaccatta ctgtcccaac tgcagagctc tcctgggcac      540

ctacaagcgt ttgtaggact cagccagacg tggagggagc cgggtgccgc aggaagtcct      600

ttccacctct catccagctt cacgcctggt ggaggttctg ccctggtggt ctcacctctc      660

cagggggccc accttcatgt cttcttttgg ggggaatacg tcgcaaaact aacaaatctc      720

caaaccccag aaattgctgc ttggagtcgt gcataggact tgcaaagaca ttccccttga      780

gtgtcagttc cacggtttcc tgcctccctg agaccctgag tcctgccatc taactgtgat      840

cattgcccta tccgaatatc ttcctgtgat ctgccatcag tggctctttt ttcctgcttc      900

catgggcctt tctggtggca gtctcaaact gagaagccac agttgcctta tttttgaggc      960

tgttctgccc agagctcggc tgaaccagcc tttagtgcct accattatct tatccgtctc     1020

ttcccgtccc tgatgacaaa gatcttgcct tacagacttt acaggcttgg ctttgagatt     1080

ctgtaactgc agacttcatt agcacacaga ttcactttaa tttcttaatt ttttttttaa     1140

atacaaggag ggggctatta acacccagta cagacatatc cacaaggtcg taaatgcatg     1200

ctagaaaaat agggctggat cttatcactg ccctgtctcc ccttgtttct ctgtgccaga     1260

tcttcagtgc ccctttccat acagggattt ttttctcata gagtaattat atgaacagtt     1320

tttatgacct ccttttggtc tgaaatactt ttgaacagaa tttctttttt ttaaaaaaaa     1380

acagagatgg ggtcttacta tgttgcccag gctggtgtcg aactcctggg ctcaagcgat     1440

ccttctgcct tggcctcccg aagtgctggg attgcaggca taagctacca tgctgggcct     1500

gaacataatt tcaagaggag gatttataaa accattttct gtaatcaaat gattggtgtc     1560

attttcccat ttgccaatgt agtctcactt aaaaaaaaaa aaaagaaaaa gaaatggata     1620

atttcatcta ctgcctttac ttggggttaa tgtgattctt aaacaccttc atcatggaac     1680

tctcagagtg gggtccgttt tggtttcctg gtggtgggtt ttgaaagata agggaaagca     1740

cattttgagc atgtctgggt accatggtgc ggatgcttgg gaaccagaac tgtttcagag     1800

gaatctaaag tctgatttta gttttcagag acacagcttg ttgtaaaaca tgagaagaca     1860

tgatttctag gactcaagca gcaagccagg attctaggtt ggctgctgtg tcatctttga     1920

agtcaagaca aagctgggct cgaccttcaa gggtcctcgt tttgataata cttcagaata     1980

gggaactcat gtgaatacta ctatgtagaa ataaaaccta gaccttgagc gaacatctgt     2040

atattggttg aaaacgatag tggtaaccat tgatccccct tcatttgatg tttggaaaat     2100

tccagtaatt atcatttttg caacgaatat ggataccaca tagtactttg gtgttacctg     2160

cttttgaaaa ataaagtctt tggttcaccc ggtgaactat ttatgagttc ttttggtgtg     2220

aagaaagggc tcatgttgca tttccagcca ttgctacaaa gaacctttat ttgttcagta     2280

acggtagaaa atccttcccg attaaaaact tcagacttgc tgaatatcct gcaatgtcaa     2340

gatgaccgat gttgagttgg gtggatttgc taacgagtca gatttgaaca tgaggctatt     2400

ggaacccaat aggcgtcatt gatggcggca agccatagct ttcaagtttt aataaaatgc     2460

acaaaagaga aaaaaaaaa                                                  2479


<210>  855
<211>  2264
<212>  DNA
<213>  homo sapiens

<400>  855
cttttgaagt taacaaaaat tgagtccctg gctgggaggt cccccgagtg ttccgctgtg       60

ggctggaggt ggcgtttctg tcgtgattta tgtggagtgg ttcaaaacag aagttaatca      120

ctcgggaagc ggacgggagg ggcggcgcta ctgcgcatgc ccgggagccg cctggagttt      180

ggaactccac attctttcag acccggcccg ctgcggggcg ttcctggggg gtagcctcaa      240

ggccagcggg gttccttcgg ctgcgtttct gtgggaggcc ctgaaacgcg cggagcttcc      300

ctctgcctcc aggctttccc agcgagagtg aaattaaact tgaaactcgg atcaactggc      360

agtcgttgtt ggtagaacgc cctaaggacc cctccccgcg ggacggaggg aggactcggg      420

acagggaatt ggccctggga gaaaacgcgc ggggggcgtc cgagacgccc cgtgaaagcc      480

gtgccgaccc ttgggaggac tgacaggtct agagacacgc gctgtctgtt gtggtgggcc      540

tcccgggaat aagtgagggg ctctgtgttt cgaggatggt tctagcgcag agccgggtgt      600

ctgccggggt gggctccccg cattgttcgg gctccggcgg gggcggctct gattcctttc      660

catggcccgc ctcccacccc gggaatcccc agtgctcctt ttccacggct tttctggcgt      720

ccccccgact ctcccgcggc actttggcct accttccccc agcgccgtgg tcctccctgg      780

cgaccccctc tgcgctcctg gggtcctcct gcgccccccc tcctccaccg gcgcgctgcc      840

cacagccgcg tgccctctcc ccggagctgg ggaccaaggc tgggccccgc cggccgcatc      900

ggtgggaact tccgcggtcc ccatcccagg gcgcacaggg tccagctcct cggcgccgac      960

tcctggaaac aatgaaaggt attgttgcag catctggcag tgagactgag gatgaggaca     1020

gcatggacat tcccttggac ctttcttcat ccgctggctc aggcaagaga aggagaaggg     1080

gcaacctacc caaggagtct gtgcagattc ttcgggattg gctgtatgag caccgttaca     1140

atgcctatcc ttcagagcaa gaaaaagcgt tgctgtccca gcaaacacac ctgtctacgc     1200

tacaggtctg taactggttc atcaacgccc gccgcaggct cctccctgac atgctgagaa     1260

aggatggcaa agatccaaat cagttcacaa tttcccgccg tggggccaag atttctgaaa     1320

cgagctctgt ggagtccgtg atgggcatca aaaacttcat gccagctcta gaggagaccc     1380

catttcattc ctgtacagct gggccaaacc caaccctagg gaggccactg tctcctaagc     1440

cgtcatcccc gggatcagtt ttggctcgtc catcagtgat ctgccatacc actgtgactg     1500

cattgaaaga tgtccctttc tctctctgcc agtcggtcgg tgtgggacaa aacacagata     1560

tacagcagat agcggccaaa aacttcacag acacctctct catgtaccca gaggacactt     1620

gtaaatctgg accaagtacg aatacacaga gtggtctttt caacactcct ccccctactc     1680

caccggacct caaccaggac ttcagtggat ttcagcttct agtggatgtt gcactcaaac     1740

gggctgcaga gatggagctt caggcaaaac ttacagctta acccattttc aagcaaaaca     1800

gttctcagaa atgtcatgat tgccggggtg aaggcaagag atgaattgca ttattttata     1860

tattttttat taatatttgc acatgggatt gctaaaacag cttcctgtta ctgagatgtc     1920

ttcaatggaa tacagtcatt ccaagaacta taaacttaaa gctactgtag aaacaaaggg     1980

ttttcttttt taaatgtttc ttggtagatt attcataatg tgagatggtt cccaatatca     2040

tgtgattttt tttttcctcc ccttcccttt ttttgttatt ttttcagact gtgcaatact     2100

tagagaacct atagcatctt ctcattccca tgtggaacag gatgcccaca tactgtctaa     2160

ttaataaatt ttccattttt tttcaaacaa gtatgaatct agttggttga tgcctttttt     2220

ttcatgacat aataaagtat tttctttaaa aaaaaaaaaa aaaa                      2264


<210>  856
<211>  4102
<212>  DNA
<213>  homo sapiens

<400>  856
agcctggttg gcagctgcgg cgcagagtcc agccgctggt gcgcggagcg gttcaccgtc       60

ttcggagcgg ttcggcccag cctttcgccc aggcgcccag gcccgctgcg cgcgtgcgtg      120

agcgcgcctg cgccgccggg gccgctgcaa ggggaggaga gaggccgcct caggaggatc      180

ccttttcccc cagaaattac tcaatgctga aacctctcaa agtggtatta gagacgctga      240

aagcaccatg gacgggtttt atgatcagca agtccctttt atggtcccag ggaaatctcg      300

atctgaggaa tgcagagggc ggcctgtgat tgacagaaag aggaagtttt tggacacaga      360

tctggctcac gattctgaag agctatttca ggatctcagt caacttcaag aggcttggtt      420

agctgaagca caagttcctg atgatgaaca gtttgtccca gattttcagt ctgataacct      480

ggtgcttcat gccccacctc caaccaagat caaacgggag ctgcacagcc cctcctctga      540

gctgtcgtct tgtagccatg agcaggctct tggtgctaac tatggagaaa agtgcctcta      600

caactattgt gcctatgata ggaagcctcc ctctgggttc aagccattaa cccctcctac      660

aacccccctc tcacccaccc atcagaatcc cctatttccc ccacctcagg caactctgcc      720

cacctcaggg catgcccctg cagctggccc agttcaaggt gtgggccccg cccccgcccc      780

ccattcgctt ccagagcctg gaccacagca gcaaacattt gcggtccccc gaccaccaca      840

tcagcccctg cagatgccaa agatgatgcc tgaaaaccag tatccatcag aacagagatt      900

tcagagacaa ctgtctgaac cctgccaccc cttccctcct cagccaggag ttcctggaga      960

taatcgcccc agttaccatc ggcaaatgtc agaacctatt gtccctgcag ctcccccgcc     1020

ccctcaggga ttcaaacaag aataccatga cccactctat gaacatgggg tcccgggcat     1080

gccagggccc ccagcacacg ggttccagtc accaatggga atcaagcagg agcctcggga     1140

ttactgcgtc gattcagaag tgcctaactg ccagtcatcc tacatgagag ggggttattt     1200

ctccagcagc catgaaggtt tttcatatga aaaagatccc cgattatact ttgacgacac     1260

ttgtgttgtg cctgagagac tggaaggcaa agtcaaacag gagcctacca tgtatcgaga     1320

ggggccccct taccagaggc gaggttccct tcagctgtgg cagttcctgg tcacccttct     1380

tgatgaccca gccaatgccc acttcattgc ctggacaggt cgaggcatgg agttcaagct     1440

gatagaaccg gaagaggttg ctcggcgctg gggcatccag aagaaccggc cagccatgaa     1500

ctatgacaag ctgagccgct ctctccgcta ttactatgaa aagggcatca tgcagaaggt     1560

ggctggagag cgatacgtct acaaatttgt ctgtgaccca gatgccctct tctccatggc     1620

tttcccggat aaccagcgtc cgttcctgaa ggcagagtcc gagtgccacc tcagcgagga     1680

ggacaccctg ccgctgaccc actttgaaga cagccccgct tacctcctgg acatggaccg     1740

ctgcagcagc ctcccctatg ccgaaggctt tgcttactaa gtttctgagt ggcggagtgg     1800

ccaaacccta gagctagcag ttcccattca ggcaaacaag ggcagtggtt ttgtttgtgt     1860

ttttggttgt tcctaaagct tgccctttga gtattatctg gagaacccaa gctgtctctg     1920

gattggcacc cttaaagaca gatacattgg ctggggagtg ggaacaggga ggggcagaaa     1980

accaccaaaa ggccagtgcc tcaactcttg attctgatga ggtttctggg aagagatcaa     2040

aatggagtct ccttaccatg gacaatacat gcaaagcaat atcttgttca ggttagtacc     2100

cgcaaaacgg gacatagtat gtgacaatct gcatcgatca tggactacta aatgccttta     2160

catagaaggg ctctgatttg cacaatttgt tgaaaaatca caaacccata gaaaagtaag     2220

taggctaagt tggggaggct caaaccatta agggttaaaa atacatctta aacattggaa     2280

agctcttcta gctgaatctg aaatattacc ccttgtctag aaaaaggggg gcagtcagaa     2340

cagctgttcc ccactccgtg gttctcaaaa tcataaacca tggctactct tgggaaccac     2400

ccggccatgt ggtcgccaag tagagcaagc cccctttctc ttcccaatca cgtggctgag     2460

tgtggatgac ttttatttta ggagaagggc gattaacact tttgacagta ttttgttttg     2520

ccctgatttg ggggattgtt ttgttttggt ggttgttttg gaaaaacagt ttataaactg     2580

atttttgtag ttttggtatt taaagcaaaa aaacgaaaaa caaaaaacaa aaacaaacct     2640

tttggtaact gtgcactgtg tcctttagcc agggccgtgc caacttatga agacactgca     2700

gcttgagagg ggctttgctg aggcttcccc ttggccatgt gaaagcccgc cttgttgcct     2760

gctttgtgct ttctgcacca gacaacctga tggaacattt gcacctgagt tgtacatttt     2820

tgaagtgtgc agggcagcct ggacacaagc ttagattctc tatgtatagt tccccgtgtt     2880

cactaacatg ccctctctgg aaagcatatg tatataacat gtgtcatgtc ctttggaaac     2940

ctggtcacct ggtgaaaacc cttgggattc ttccctgggc atgactgatg acaatttcca     3000

tttcatcagt ttgttttgtt ttcctttttc tttaaatctt ggactttaaa ccctacctgt     3060

gtgattcagt agggtttgag acttacgtgt gatactgaca ggtaagcaac agtgctagca     3120

ttctagattc ctgccttttt ttaaaaagaa attattctca ttgctgtatt atattggaaa     3180

agttttaaac aaccaagcta aagctatgtg aaagttgagc tcaaagtaga ggaaaagtta     3240

ctggtggtac cttgctgcct gctctgctgg tagaattctg tgctccccgt gacacttagt     3300

acattaagaa tgactacact gttcctcgta tgtgaaggag gcagtgctga ctccgtgagt     3360

gtgagacacg tgctttgaac tgcttttcta ttcatggagc actccatagt ctcaaactgt     3420

cccccttatg accaacagca catttgtgaa gaggttcgca gggataaggg gtgcacttta     3480

tagctatgga aacatgagat tctcctctat tggaagctaa ttagcccaca aaggtggtaa     3540

acctgtagat tgggccttaa ttagcattgt actctaatca aaggactctt tctaaaccat     3600

atttatagct ttcttaacct acacatagtc tatacataga tgcatatttt acccccagct     3660

ggctagagat ttatttgttg taaatgctgt atagatttgg ttttcctttc tttacttacc     3720

ctggtttgga tttttttttt ttttcttttg aatggattta tgctgtctta gcaatatgac     3780

aataatcctc tgtagcttga gctacccctc ccctgctgta acttacgtga cctgtgctgt     3840

cactgggcat aggacagcgg catcacggtt gcattcccat tggactcatg cacctcccgg     3900

atggtttttg tttttttcgg gggttctttg gggtttgttt gtttgcttct tttccagagt     3960

gtggaaagtc tacagtgcag aaaggcttga acctgccagc tgatttgaaa tactttcccc     4020

tgcgcagggc cgtatgcatc ctgccaagct gcgttatatt ctgtactgtg tacaataaag     4080

aagtttgctt ttcgtttacc aa                                              4102


<210>  857
<211>  2679
<212>  DNA
<213>  homo sapiens

<400>  857
agagccagcg gacggaacca ttccaaacag cctagtctcg tgctgagagc ctctccggtt       60

tcacgctgag acccgctcac ccccgctctg gccccttaga tgctattttg gcccgagtgt      120

cacgtcgggc gctctttaga gaggactggg acaagagttg cggacgcgaa gaacgagtaa      180

gcggtggttc atccctcctg accccacccc cgtggcctgg cccgatggtc gcgcccgggg      240

ttgcgagatt tgcgcctgcg cagtgcggcg cctagaggga aagcgagagg gagacggacg      300

ttgagagaac gaggaggaag gagagaaaat ggcgtccacg gattacagta cctatagcca      360

agctgcagcg cagcagggct acagtgctta caccgcccag cccactcaag gatatgcaca      420

gaccacccag gcatatgggc aacaaagcta tggaacctat ggacagccca ctgatgtcag      480

ctatacccag gctcagacca ctgcaaccta tgggcagacc gcctatgcaa cttcttatgg      540

acagcctccc actggttata ctactccaac tgccccccag gcatacagcc agcctgtcca      600

ggggtatggc actggtgctt atgataccac cactgctaca gtcaccacca cccaggcctc      660

ctatgcagct cagtctgcat atggcactca gcctgcttat ccagcctatg ggcagcagcc      720

agcagccact gcacctacaa gaccgcagga tggaaacaag cccactgaga ctagtcaacc      780

tcaatctagc acagggggtt acaaccagcc cagcctagga tatggacaga gtaactacag      840

ttatccccag gtacctggga gctaccccat gcagccagtc actgcacctc catcctaccc      900

tcctaccagc tattcctcta cacagccgac tagttatgat cagagcagtt actctcagca      960

gaacacctat gggcaaccga gcagctatgg acagcagagt agctatggtc aacaaagcag     1020

ctatgggcag cagcctccca ctagttaccc accccaaact ggatcctaca gccaagctcc     1080

aagtcaatat agccaacaga gcagcagcta cgggcagcag agttcattcc gacaggacca     1140

ccccagtagc atgggtgttt atgggcagga gtctggagga ttttccggac caggagagaa     1200

ccggagcatg agtggccctg ataaccgggg caggggaaga gggggatttg atcgtggagg     1260

catgagcaga ggtgggcggg gaggaggacg cggtggaatg ggcagcgctg gagagcgagg     1320

tggcttcaat aagcctggtg gacccatgga tgaaggacca gatcttgatc taggcccacc     1380

tgtagatcca gatgaagact ctgacaacag tgcaatttat gtacaaggat taaatgacag     1440

tgtgactcta gatgatctgg cagacttctt taagcagtgt ggggttgtta agatgaacaa     1500

gagaactggg caacccatga tccacatcta cctggacaag gaaacaggaa agcccaaagg     1560

cgatgccaca gtgtcctatg aagacccacc cactgccaag gctgccgtgg aatggtttga     1620

tgggaaagat tttcaaggga gcaaacttaa agtctccctt gctcggaaga agcctccaat     1680

gaacagtatg cggggtggtc tgccaccccg tgagggcaga ggcatgccac caccactccg     1740

tggaggtcca ggaggcccag gaggtcctgg gggacccatg ggtcgcatgg gaggccgtgg     1800

aggagataga ggaggcttcc ctccaagagg accccggggt tcccgaggga acccctctgg     1860

aggaggaaac gtccagcacc gagctggaga ctggcagtgt cccaatccgg gttgtggaaa     1920

ccagaacttc gcctggagaa cagagtgcaa ccagtgtaag gccccaaagc ctgaaggctt     1980

cctcccgcca ccctttccgc ccccgggtgg tgatcgtggc agaggtggcc ctggtggcat     2040

gcggggagga agaggtggcc tcatggatcg tggtggtccc ggtggaatgt tcagaggtgg     2100

ccgtggtgga gacagaggtg gcttccgtgg tggccggggc atggaccgag gtggctttgg     2160

tggaggaaga cgaggtggcc ctggggggcc ccctggacct ttgatggaac agatgggagg     2220

aagaagagga ggacgtggag gacctggaaa aatggataaa ggcgagcacc gtcaggagcg     2280

cagagatcgg ccctactaga tgcagagacc ccgcagagct gcattgacta ccagatttat     2340

tttttaaacc agaaaatgtt ttaaatttat aattccatat ttataatgtt ggccacaaca     2400

ttatgattat tccttgtctg tactttagta tttttcacca tttgtgaaga aacattaaaa     2460

caagttaaat ggtagtgtgc ggagtttttt tttcttcctt cttttaaaaa tggttgttta     2520

agactttaac aatgggaacc ccttgtgagc atgctcagta tcattgtgga gaaccaagag     2580

ggcctcttaa ctgtaacaat gttcatggtt gtgatgtttt tttttttttt ttaaataaaa     2640

ttccaaatgt ttataaagag tcaaaaaaaa aaaaaaaaa                            2679


<210>  858
<211>  2694
<212>  DNA
<213>  homo sapiens

<400>  858
agagccagcg gacggaacca ttccaaacag cctagtctcg tgctgagagc ctctccggtt       60

tcacgctgag acccgctcac ccccgctctg gccccttaga tgctattttg gcccgagtgt      120

cacgtcgggc gctctttaga gaggactggg acaagagttg cggacgcgaa gaacgagtaa      180

gcggtggttc atccctcctg accccacccc cgtggcctgg cccgatggtc gcgcccgggg      240

ttgcgagatt tgcgcctgcg cagtgcggcg cctagaggga aagcgagagg gagacggacg      300

ttgagagaac gaggaggaag gagagaaaat ggcgtccacg gattacagta cctatagcca      360

agctgcagcg cagcagggct acagtgctta caccgcccag cccactcaag gatatgcaca      420

gaccacccag gcatatgggc aacaaagcta tggaacctat ggacagccca ctgatgtcag      480

ctatacccag gctcagacca ctgcaaccta tgggcagacc gcctatgcaa cttcttatgg      540

acagcctccc actgtagaag ggaccagtac aggttatact actccaactg ccccccaggc      600

atacagccag cctgtccagg ggtatggcac tggtgcttat gataccacca ctgctacagt      660

caccaccacc caggcctcct atgcagctca gtctgcatat ggcactcagc ctgcttatcc      720

agcctatggg cagcagccag cagccactgc acctacaaga ccgcaggatg gaaacaagcc      780

cactgagact agtcaacctc aatctagcac agggggttac aaccagccca gcctaggata      840

tggacagagt aactacagtt atccccaggt acctgggagc taccccatgc agccagtcac      900

tgcacctcca tcctaccctc ctaccagcta ttcctctaca cagccgacta gttatgatca      960

gagcagttac tctcagcaga acacctatgg gcaaccgagc agctatggac agcagagtag     1020

ctatggtcaa caaagcagct atgggcagca gcctcccact agttacccac cccaaactgg     1080

atcctacagc caagctccaa gtcaatatag ccaacagagc agcagctacg ggcagcagag     1140

ttcattccga caggaccacc ccagtagcat gggtgtttat gggcaggagt ctggaggatt     1200

ttccggacca ggagagaacc ggagcatgag tggccctgat aaccggggca ggggaagagg     1260

gggatttgat cgtggaggca tgagcagagg tgggcgggga ggaggacgcg gtggaatggg     1320

cgctggagag cgaggtggct tcaataagcc tggtggaccc atggatgaag gaccagatct     1380

tgatctaggc ccacctgtag atccagatga agactctgac aacagtgcaa tttatgtaca     1440

aggattaaat gacagtgtga ctctagatga tctggcagac ttctttaagc agtgtggggt     1500

tgttaagatg aacaagagaa ctgggcaacc catgatccac atctacctgg acaaggaaac     1560

aggaaagccc aaaggcgatg ccacagtgtc ctatgaagac ccacccactg ccaaggctgc     1620

cgtggaatgg tttgatggga aagattttca agggagcaaa cttaaagtct cccttgctcg     1680

gaagaagcct ccaatgaaca gtatgcgggg tggtctgcca ccccgtgagg gcagaggcat     1740

gccaccacca ctccgtggag gtccaggagg cccaggaggt cctgggggac ccatgggtcg     1800

catgggaggc cgtggaggag atagaggagg cttccctcca agaggacccc ggggttcccg     1860

agggaacccc tctggaggag gaaacgtcca gcaccgagct ggagactggc agtgtcccaa     1920

tccgggttgt ggaaaccaga acttcgcctg gagaacagag tgcaaccagt gtaaggcccc     1980

aaagcctgaa ggcttcctcc cgccaccctt tccgcccccg ggtggtgatc gtggcagagg     2040

tggccctggt ggcatgcggg gaggaagagg tggcctcatg gatcgtggtg gtcccggtgg     2100

aatgttcaga ggtggccgtg gtggagacag aggtggcttc cgtggtggcc ggggcatgga     2160

ccgaggtggc tttggtggag gaagacgagg tggccctggg gggccccctg gacctttgat     2220

ggaacagatg ggaggaagaa gaggaggacg tggaggacct ggaaaaatgg ataaaggcga     2280

gcaccgtcag gagcgcagag atcggcccta ctagatgcag agaccccgca gagctgcatt     2340

gactaccaga tttatttttt aaaccagaaa atgttttaaa tttataattc catatttata     2400

atgttggcca caacattatg attattcctt gtctgtactt tagtattttt caccatttgt     2460

gaagaaacat taaaacaagt taaatggtag tgtgcggagt ttttttttct tccttctttt     2520

aaaaatggtt gtttaagact ttaacaatgg gaaccccttg tgagcatgct cagtatcatt     2580

gtggagaacc aagagggcct cttaactgta acaatgttca tggttgtgat gttttttttt     2640

tttttttaaa taaaattcca aatgtttata aagagtcaaa aaaaaaaaaa aaaa           2694


<210>  859
<211>  3195
<212>  DNA
<213>  homo sapiens

<400>  859
gtagccacac ccacgccccc acaggcccgg cttccctgcc cagcggctcc aacctccagc       60

ctgggcaccc agacccagag ggctgctggg agggacatgc ctcacccctt ttgctccagc      120

tggaggggag ggagtctgtg ggagctggcc agagcgtggc agaaggcaga gaagtgaacg      180

ccccagcaaa agtgctcctc acatgggtca actgttccag tgtgcggtgg gccacccggg      240

ttcaagacat cttcacagct gggaagctcc tggccttggc cctgattatc atcatgggga      300

ttgtacagat atgcaaagga gagtacttct ggctggagcc aaagaatgca tttgagaatt      360

tccaggaacc tgacatcggc ctcgtcgcac tggctttcct tcagggctcc tttgcctatg      420

gaggctggaa ctttctgaat tacgtgactg aggagcttgt tgatccctac aagaaccttc      480

ccagagccat cttcatctcc atcccactgg tcacatttgt gtatgtcttt gccaatgtcg      540

cttatgtcac tgcaatgtcc ccccaggagc tgctggcatc caacgccgtc gctgtgactt      600

ttggagagaa gctcctagga gtcatggcct ggatcatgcc catttctgtt gccctgtcca      660

catttggagg agttaatggg tctctcttca cctcctctcg gctgttcttc gctggagccc      720

gagagggcca ccttcccagt gtgttggcca tgatccacgt gaagcgctgc accccaatcc      780

cagccctgct cttcacatgc atctccaccc tgctgatgct ggtcaccagc gacatgtaca      840

cactcatcaa ctatgtgggc ttcatcaact acctcttcta tggggtcacg gttgctggac      900

agatagtcct tcgctggaag aagcctgata tcccccgccc catcaagatc aacctgctgt      960

tccccatcat ctacttgctg ttctgggcct tcctgctggt cttcagcctg tggtcagagc     1020

cggtggtgtg tggcattggc ctggccatca tgctgacagg agtgcctgtc tatttcctgg     1080

gtgtttactg gcaacacaag cccaagtgtt tcagtgactt cattgagctg ctaaccctgg     1140

tgagccagaa gatgtgtgtg gtcgtgtacc ccgaggtgga gcggggctca gggacagagg     1200

aggctaatga ggacatggag gagcagcagc agcccatgta ccaacccact cccacgaagg     1260

acaaggacgt ggcggggcag ccccagccct gaggaccacc attccctggc tactctctcc     1320

ttcctccccc ttttatccta cctccctgcc ttggtcctgc caacacatgc gagtacacac     1380

acacccctct ctctgctttt gtcaggcagt ggtaggactt tggtgtgggt ggtgagaaat     1440

tgtaaacaaa aactgacatt catacccaaa gaaccagcct ctcaccccag ggtccatgtc     1500

ccaggcccca ctccagtgct gcccacactc ccagctgctg gaggagaggg gagatgccaa     1560

ggtgccctgc aggacctccc tccgggccac accctcagct gcctcttcag gaaccggagc     1620

tcattactgc cttccctccc agggaggccc cttcagagag gagaggccac aggagctgca     1680

ttgtgggggg acaggctcaa gcaattctgt ccccatcaag gggtcagctg gagagaccca     1740

agaccctatc tgttcaccag ggacccaaaa tccaagggga tgcttccctc tgccctcttt     1800

cctgcccctc cccatcatac ctgcacccac cccagccagg gctccctgtc cagaattcgg     1860

ttctcctcag gacgccaact cccagagcta aggaccaagg agaagaacag cctctccacc     1920

cccaagccag gcggttgagg aacatattga gaaaggttca gattgcagaa acccagccct     1980

gcccctgcct cctgcatcca gcccccaaca tggtgccaaa gcttccagaa gccaaaaagc     2040

ttctgatttt taaggtagtg ggcatctctc tcctaatgac gaagctgctc agcaactcca     2100

cctgcccgcc gcaggaagga gcagtcccct gctatccctg cagccactcc cagcacaccc     2160

gcacacagcc agcaccaccg cccccaccgt gcacttctcc tctctgggcc ttggcttggg     2220

accaggtacg aaggatcccc aagcccttca ggcctgagat cagagccaga tcagccttaa     2280

gtcacctccc atccaagaac ttggcctaaa aatactcccc tatttctaac cctcaggacg     2340

gatctgatat taaatgcctt ccctgggagg aagggtgctt tccccctccc tagaggtgcc     2400

cattccatac cctgggagac tgaggagagc attggctgaa gcccagttcc tttcccatcc     2460

atccccaact ccaataatcc cccactcctc gcaggtctca gtgtcatgct gtcttggggc     2520

agggtgaaag ggtagtggca gcagggcgcc cactctggag atcctcaaaa aaggccctcc     2580

tctgtggctg gcagcctctg acctttccct gggcttcaaa ggaaggctat ggagtttgct     2640

gtgggccctg caaccttccc agccactcct gctgcactaa ggacttagga tccttttatc     2700

acaaatcggg attctctccc ccaccccgaa ttctgtctgc ttaaactgga atacacagga     2760

gcccttcctg gcctggatgg tgtctcccag cttccccgcc cagcttgccc accccatagt     2820

tggtgagatg ccaagtttgg tctgagttgt gaccccttca gagtagatgc ccggcaggct     2880

ggggttggcc cctggagggt caggggacca tcttcttatt ccctcttttc tcattcctcc     2940

aacttcctcc cctccttcaa ttattttttt gtaaagttga tgccttactt tttggataaa     3000

tatttttgaa gctggtattt ctatttcttt tggatttttt ttaatgtaag gttgttttgg     3060

gggatggagt tagaacctta atgataattt ctttcgtttg gtgtaggttt tagagatttg     3120

ttttgtggag aggttttttt cttttgatgt aataaaattt aaaatggaaa tgaaaaaaaa     3180

aaaaaaaaaa aaaaa                                                      3195


<210>  860
<211>  7949
<212>  DNA
<213>  homo sapiens

<400>  860
gggagaggga gacgcaggcg gcgaaacggc agaggagccg agccccctcc gcccaaggcg       60

ccctccctcc gtccgcgcac aggcgccgtc gcttggagga gcaaggtgcc tcccagcccg      120

caggggcgcc gcgcgcaagc ccgcgggctc ttcggtggct ctgccccggg actgcacctg      180

gaggcggccc cggacgggga tggtcagcgg ctgctgccgt ctggctcgcg agcgggacgc      240

tgtgagggca ccatggcgct gactcccggg tgggggtcct cggcggggcc ggtccggccg      300

gagctctggc tgctgctgtg ggcagccgcg tggcgcctgg gtgcctcggc gtgccccgcc      360

ctctgcacct gcaccggaac cacggtggac tgccacggca cggggctgca ggccattccc      420

aagaatatac ctcggaacac cgagcgcctg gaactcaatg gcaacaacat cactcggatc      480

cataagaatg actttgcggg gctcaagcag ctgcgggtgc tgcagctgat ggagaaccag      540

attggagcag tggaacgtgg tgcttttgat gacatgaagg agctggagcg gctgcgactg      600

aaccgaaacc agctgcacat gttaccggaa ctgctgttcc agaacaacca ggctttgtca      660

agactggact tgagtgagaa cgccatccag gccatcccca ggaaagcttt tcggggagct      720

acggacctta aaaatttaca gctggacaag aaccagatca gctgcattga ggaaggggcc      780

ttccgtgctc tgcgggggct ggaggtgctg accctgaaca acaacaatat caccaccatc      840

cccgtgtcca gcttcaacca tatgcccaag ctacggacct tccgcctgca ctccaaccac      900

ctgttttgcg actgccacct ggcctggctc tcgcagtggc tgaggcagcg gccaaccatc      960

gggctcttca cccagtgctc gggcccagcc agcctgcgtg gcctcaatgt ggcagaggtc     1020

cagaagagtg agttcagctg ctcaggccag ggagaagcgg ggcgcgtgcc cacctgcacc     1080

ctgtcctccg gctcctgccc ggccatgtgc acctgcagca atggcatcgt ggactgtcgt     1140

ggaaaaggcc tcactgccat cccggccaac ctgcccgaga ccatgacgga gatacgcctg     1200

gagctgaacg gcatcaagtc catccctcct ggagccttct caccctacag aaagctacgg     1260

aggatagacc tgagcaacaa tcagatcgct gagattgcac ccgacgcctt ccagggcctc     1320

cgctccctga actcgctggt cctctatgga aacaagatca cagacctccc ccgtggtgtg     1380

tttggaggcc tatacaccct acagctcctg ctcctgaatg ccaacaagat caactgcatc     1440

cggcccgatg ccttccagga cctgcagaac ctctcactgc tctccctgta tgacaacaag     1500

atccagagcc tcgccaaggg cactttcacc tccctgcggg ccatccagac tctgcacctg     1560

gcgcagaacc ctttcatttg cgactgtaac ctcaagtggc tggcagactt cctgcgcacc     1620

aatcccatcg agacgagtgg tgcccgctgt gccagtcccc ggcgcctcgc caacaagcgc     1680

atcgggcaga tcaagagcaa gaagttccgg tgctcagcca aagagcagta cttcattcca     1740

ggcacggagg attaccagct gaacagcgag tgcaacagcg acgtggtctg tccccacaag     1800

tgccgctgtg aggccaacgt ggtggagtgc tccagcctga agctcaccaa gatccctgag     1860

cgcatccccc agtccacggc agaactgcga ttgaataaca atgagatttc catcctggag     1920

gccactggga tgtttaaaaa acttacacat ctgaagaaaa tcaatctgag caacaacaag     1980

gtgtcagaaa ttgaagatgg ggccttcgag ggcgcagcct ctgtgagcga gctgcaccta     2040

actgccaacc agctggagtc catccggagc ggcatgttcc ggggtctgga tggcttgagg     2100

accctaatgc tgcggaacaa ccgcatcagc tgcatccaca acgacagctt cacgggcctg     2160

cgcaacgtcc ggctcctctc gctctacgac aaccagatca ccaccgtatc cccaggagcc     2220

ttcgacaccc tccagtccct ctccacactg aatctcctgg ccaacccttt caactgcaac     2280

tgccagctgg cctggctagg aggctggcta cggaagcgca agatcgtgac ggggaacccg     2340

cgatgccaga accctgactt tttgcggcag attcccctgc aggacgtggc cttccctgac     2400

ttcaggtgtg aggaaggcca ggaggagggg ggctgcctgc cccgcccaca gtgcccacag     2460

gagtgcgcct gcctggacac cgtggtccga tgcagcaaca agcacctgcg ggccctgccc     2520

aagggcattc ccaagaatgt cacagaactc tatttggacg ggaaccagtt cacgctggtt     2580

ccgggacagc tgtctacctt caagtacctg cagctcgtgg acctgagcaa caacaagatc     2640

agttccttaa gcaattcctc cttcaccaac atgagccagc tgaccactct gatcctcagc     2700

tacaatgccc tgcagtgcat cccgcctttg gccttccagg gactccgctc cctgcgcctg     2760

ctgtctctcc acggcaatga catctccacc ctccaagagg gcatctttgc agacgtgacc     2820

tccctgtctc acctggccat tggtgccaac cccctatact gtgactgcca cctccgctgg     2880

ctgtccagct gggtgaagac tggctacaag gaaccgggca ttgctcgttg tgctgggccc     2940

caggacatgg agggcaagct gctcctcacc acgcctgcca agaagtttga atgccaaggt     3000

cctccaacgc tggctgtcca ggccaagtgt gatctctgct tgtccagtcc gtgccagaac     3060

cagggcacct gccacaacga cccccttgag gtgtacaggt gcgcctgccc cagcggctat     3120

aagggtcgag actgtgaggt gtccctggac agctgttcca gtggcccctg tgaaaatggg     3180

ggcacctgcc atgcacagga gggcgaggat gccccgttca cgtgctcctg tcccaccggc     3240

tttgaaggac caacctgtgg ggtgaacaca gatgactgtg tggatcatgc ctgtgccaat     3300

gggggcgtct gtgtggatgg tgtgggcaac tacacctgcc agtgccccct gcagtatgag     3360

ggaaaggcct gtgagcagct ggtggacttg tgctctccgg atctgaaccc atgtcaacac     3420

gaggcccagt gtgtgggcac cccggatggg cccaggtgtg agtgcatgcc aggttatgca     3480

ggtgacaact gcagtgagaa ccaggatgac tgcagggacc accgctgcca gaatggggcc     3540

cagtgtatgg atgaagtcaa cagctactcc tgcctctgtg ctgagggcta cagtggacag     3600

ctctgtgaga tccctcccca tctgcctgcc cccaagagcc cctgtgaggg gactgagtgc     3660

cagaatgggg ccaactgtgt ggaccagggc aacaggcctg tgtgccagtg cctcccaggc     3720

ttcggtggcc ctgagtgtga gaagttgctc agtgtcaact ttgtggatcg ggacacttac     3780

ctgcagttca ctgacctgca aaactggcca cgggccaaca tcacgttgca ggtctccacg     3840

gcagaggaca atgggatcct tctgtacaac ggggacaacg accacattgc agttgagctg     3900

taccagggcc atgtgcgtgt cagctacgac ccaggcagct accccagctc tgccatctac     3960

agtgctgaga cgatcaacga tgggcaattc cacaccgttg agctggttgc ctttgaccag     4020

atggtgaatc tctccattga tggcgggagc cccatgacca tggacaactt tggcaaacat     4080

tacacgctca acagcgaggc gccactctat gtgggaggga tgcccgtgga tgtcaactca     4140

gctgccttcc gcctgtggca gatcctcaac ggcaccggct tccacggttg catccgaaac     4200

ctgtacatca acaacgagct gcaggacttc accaagacgc agatgaagcc aggcgtggtg     4260

ccaggctgcg aaccctgccg caagctctac tgcctgcatg gcatctgcca gcccaatgcc     4320

accccagggc ccatgtgcca ctgcgaggct ggctgggtgg gcctgcactg tgaccagccc     4380

gctgacggcc cctgccatgg ccacaagtgt gtccatgggc aatgcgtgcc cctcgacgct     4440

ctttcctaca gctgccagtg ccaggatggg tactcggggg cactgtgcaa ccaggccggg     4500

gccctggcag agccctgcag aggcctgcag tgcctgcatg gccactgcca ggcctcaggc     4560

accaaggggg cacactgtgt gtgtgacccc ggcttttcgg gcgagctgtg tgagcaagag     4620

tccgagtgcc ggggggaccc tgtccgggac tttcaccagg tccagagggg ctatgccatc     4680

tgccagacca cgcgccccct gtcatgggtg gagtgccggg gctcgtgccc aggccagggc     4740

tgctgccagg gccttcggct gaagcggagg aagttcacct ttgagtgcag cgatgggacc     4800

tcttttgccg aggaggtgga aaagcccacc aagtgtggct gtgccctctg cgcatagcgc     4860

tgggcgtgga caggccggtg agggcgggca aggggcccca gccgctgcag cagcggagac     4920

agtcgccagc agctgggctg gggtgcaggt catcacagga cggctcctgg gcagctgggc     4980

cctcctgggt ggggtggtgc cagagcagcc ttttaaaagc aaattgcgcc atagctgggg     5040

gcagcggggg tgggcgaggc ctgagctgcg ggctgccctc tccggaagtg ccttgcacaa     5100

ataggcgctt aataaatatt tgttgagtga atgtgtgcgt gaggtcaggc caagaagtgc     5160

agaacgatga cacccctcct tacctgctat ctgaatctgg agaagaaaaa tgacagcctt     5220

ccaaaccaac ccttcccttt ggcctgtggc ccaggctggc ttggaactgg gtctgtggcc     5280

ccagaagcct cttacccctc tgcgggcaac catgaagtac tgtcagcctc cccgggaagc     5340

cagcctggtt cattctgctg ctacagaatc tgctggtggt aggccaggct ctggagcggg     5400

ggtgccgcct cctgctggcc agggagggtc ggacccttgc cccctgggct gactggcagc     5460

tctgcagcca cggcttggga acgaggctgt gggtggaggt ggttcttagg accaggcctc     5520

tgaatcctaa agttctagca tgactactgt agctgcgagg gcttatgtgg aggaaacagt     5580

cacaggggct gctcagggtg gcagacccca ctaaagaggg cagagggttc tttgctctag     5640

ataaacaaac atcatctgcc tccagacact ggccacagta ggagtattgg tcctgggctt     5700

ccccagccac cagtcagcca caagctgtcg gtgacctatt ggtagaggga ctgggtgtga     5760

gggtctgggc cagggtgctt gacctgggag cagctggttc agagtccttc acaccgcagg     5820

ccagtaggga gcagtggaag ggacagtgct ccaggcattg ggaagtccct gctggctcta     5880

tcactcgggg caaacttctc cccacctggg ccttgggttc ttcagctata aaatggccag     5940

aggtgggggg cgggatgact aaaggaacag tgcagactcc cccactgtgg tcttgggagg     6000

ccagaggagt tagaagacct atctatctat ctatctatct acattgatca catcaaaagt     6060

atttatgtgc ctaacccggg gctggggatt gtggacgttc tggcctaatg gacagatgtg     6120

aactcatccc agagcatcgc aggaatgacc aggatgcccg ggaagagttg agctgagtgg     6180

gggctccagc cacagacagc ggcccaggcc agggagttgc tggcaacgaa ggagccagtg     6240

gtggaagaag aagaggccct gaatatacga ttgcctgccc acgttgtctt ctcttccata     6300

cacagtgaaa atgtagaaag atggtttgtg aggccaaact gtgaatgggc taaagggagg     6360

caaagttgca ctctccttcc ccagagggct caccaagagg gcacaccccc gggggttctg     6420

gtgggcaacg ggggtgagca tgtccctgcc ctggctccct ccatctgtga ccaggaggca     6480

tggctgggtg tatgttcagg tgaggctcag agtggcattg tgtccctgtc ccctgcccag     6540

ggcagtgagg ggagcccttg atgctgatta gaaggctaga actggggtag aggtgcctgg     6600

catgtctcat gccatgggga ctcaatctag caactgtgag tcctggggtc cctgtgatgg     6660

gaagagggca gtgccctgcc caatgtggca ggtgtcctca tggcaggatc tgcccctcac     6720

cagggggctg ggatctactt gcttggagct ctgagcaagg ccacaatgcc cgcccccacc     6780

cccaagtaga ctgcagcctg ggcctcatgg ggcttctccc aggcccacat ggcatccctc     6840

tctgagtttc caggccaccg tgggaccctg cagagcatct gcaccgggct ggatagggca     6900

gaaaagctca agggcagcta gcttgcctct tccctggaag aaaggtgctc tgggactcac     6960

caaccctgag aaagatagct ttcctggcca ccaccattcc ccaccaccct ggagaagcca     7020

attcccaggc ttgaagggca ctggctggca ggaggcctct tcattctgca ggaggtggaa     7080

aggacacctg tagacaggtg atgctcaccc ctcacctggc gccatggggc tgggaggtga     7140

gcggctggca tgtttgttcc tagggagcac catgtgagct taaggctccc ctgaccggcc     7200

ccaccacatg gcccagcctc ctagcacagc agcgctgacc tcagtgcagt ctgaggattg     7260

gaatccacca tgagatgatg tgagagctgt gtgccccagg atcaactttt tctccaactt     7320

ggccatcagc cagcgagttg ctaaggacct gagtcagcac tcacgttgcc tattcacact     7380

ccgcttgaaa gtccggaagg tggctactgc aaaatcaccc ctctgagaag tcctctctcc     7440

acatcttgtc cccctttgtg aagaccccta gttcgctctg cattttaggc atgaagagat     7500

acagcagggt gcgtccggag ggagctgtgg ccttgcaaca ccactggcaa cagggccggg     7560

gctcccggtg aaggtgtcag gaagtggaaa aggctggact ttgtctcctc tttgcctgct     7620

ggtagcctaa ccgcaaaagt atctctttat acagaatact tacagattct aatatatatt     7680

tgtatttcat tttgttacag tatttttata tgttaaagtc aacatccagc gtcttgtttt     7740

gcctttcaga tgctatgtgg tcgtggcacg ttttgttggg ggtttctgta gtcgtcttgt     7800

ttggatcaac tcctagaggc tggtttagaa caggcccatg agggagctgc acctgccctg     7860

gaagtattgt tttagactat gtcgatattg tctgttgtct tccatgtgaa catgacattg     7920

agtcactctg caaaaaaaaa aaaaaaaaa                                       7949


<210>  861
<211>  4417
<212>  DNA
<213>  homo sapiens

<400>  861
ctccttcctg caagaagcgt tgcccgttgg ctagctgctc ggtggggatc tgcctgccct       60

gggggcgccg cccgcgctcc ccgcggtgct ctcgctcctg ggctgcgcca gtccgaggcg      120

gtgccggctc ctttgcctcc ccgagtcgca gatgctgcgg gcgcctccgg gaaaagatct      180

gggcggcgcg ctcgctcgat ggacacagga agatccagaa gctagtggca catctagcaa      240

cagagccaga tcagaaccca ggttggaggt ggagtagttc agaatcaact gacgcagccg      300

ggaattgagc tttgcaaagc cacttgcaag gaagggaagc atctgcccaa ccctccccca      360

ccgcgcgccc tggatcctct gcctgccccc tcccccgtga cgtcacccta gtcctgtccc      420

ggggagcctg caaagcctct cagattcaaa ctgctagacg cactgctgcc accgccaccg      480

aattggaaac gcgcgcccag gctccgtcgt cgccttcgcc cgccgaccgg gccagccggc      540

tctccgacct ccctacagaa tcgcacccca gtccctccct ggcagctcgg cttccctcag      600

ctccaactct tctcttccgc tcctgcctcc tgtcggattt ttaatttctg cgcaccccca      660

gtcaaattaa atcaaccaac aaaaagcagg gcatcccccc tggaagcagc gtcttatttt      720

accttgttct cccacttcct gaagatgcta aactcctggt ggactgcaga ggagagggat      780

tcagtcttct cctgatgtcg attgcgattt ctgctgggag ctcaagacgg gcgagctgcc      840

cgagatctct tcgagatacc ccaggggagg aggagatggg caggatttag taggacaact      900

cggttactaa tgacttggcg gctggctgcg accccccggg aaatcaggtt tgcctgtagg      960

tacctgagtt gacaccgaag gtgcctaaag atgctgagcg gcgtttggtt cctcagtgtg     1020

ttaaccgtgg ccgggatctt acagacagag agtcgcaaaa ctgccaaaga catttgcaag     1080

atccgctgtc tgtgcgaaga aaaggaaaac gtactgaata tcaactgtga gaacaaagga     1140

tttacaacag ttagcctgct ccagcccccc cagtatcgaa tctatcagct ttttctcaat     1200

ggaaacctct tgacaagact gtatccaaac gaatttgtca attactccaa cgcggtgact     1260

cttcacctag gtaacaacgg gttacaggag atccgaacgg gggcattcag tggcctgaaa     1320

actctcaaaa gactgcatct caacaacaac aagcttgaga tattgaggga ggacaccttc     1380

ctaggcctgg agagcctgga gtatctccag gccgactaca attacatcag tgccatcgag     1440

gctggggcat tcagcaaact taacaagctc aaagtgctca tcctgaatga caaccttctg     1500

ctttcactgc ccagcaatgt gttccgcttt gtcctgctga cccacttaga cctcaggggg     1560

aataggctaa aagtaatgcc ttttgctggc gtccttgaac atattggagg gatcatggag     1620

attcagctgg aggaaaatcc atggaattgc acttgtgact tacttcctct caaggcctgg     1680

ctagacacca taactgtttt tgtgggagag attgtctgtg agactccctt taggttgcat     1740

gggaaagacg tgacccagct gaccaggcaa gacctctgtc ccagaaaaag tgccagtgat     1800

tccagtcaga ggggcagcca tgctgacacc cacgtccaaa ggctgtcacc tacaatgaat     1860

cctgctctca acccaaccag ggctccgaaa gccagccggc cgcccaaaat gagaaatcgt     1920

ccaactcctc gagtgactgt gtcaaaggac aggcaaagtt ttggacccat catggtgtac     1980

cagaccaagt ctcctgtgcc tctcacctgt cccagcagct gtgtctgcac ctctcagagc     2040

tcagacaatg gtctgaatgt aaactgccaa gaaaggaagt tcactaatat ctctgacctg     2100

cagcccaaac cgaccagtcc aaagaaactc tacctaacag ggaactatct tcaaactgtc     2160

tataagaatg acctcttaga atacagttct ttggacttac tgcacttagg aaacaacagg     2220

attgcagtca ttcaggaagg tgcctttaca aacctgacca gtttacgcag actttatctg     2280

aatggcaatt accttgaagt gctgtaccct tctatgtttg atggactgca gagcttgcaa     2340

tatctctatt tagagtataa tgtcattaag gaaattaagc ctctgacctt tgatgctttg     2400

attaacctac agctactgtt tctgaacaac aaccttcttc ggtccttacc tgataatata     2460

tttgggggga cggccctaac caggctgaat ctgagaaaca accatttttc tcacctgccc     2520

gtgaaagggg ttctggatca gctcccggct ttcatccaga tagatctgca ggagaacccc     2580

tgggactgta cctgtgacat catggggctg aaagactgga cagaacatgc caattcccct     2640

gtcatcatta atgaggtgac ttgcgaatct cctgctaagc atgcagggga gatactaaaa     2700

tttctgggga gggaggctat ctgtccagac agcccaaact tgtcagatgg aaccgtcttg     2760

tcaatgaatc acaatacaga cacacctcgg tcgcttagtg tgtctcctag ttcctatcct     2820

gaactacaca ctgaagttcc actgtctgtc ttaattctgg gattgcttgt tgttttcatc     2880

ttatctgtct gttttggggc tggtttattc gtctttgtct tgaaacgccg aaagggagtg     2940

ccgagcgttc ccaggaatac caacaactta gacgtaagct cctttcaatt acagtatggg     3000

tcttacaaca ctgagactca cgataaaaca gacggccatg tctacaacta tatcccccca     3060

cctgtgggtc agatgtgcca aaaccccatc tacatgcaga aggaaggaga cccagtagcc     3120

tattaccgaa acctgcaaga gttcagctat agcaacctgg aggagaaaaa agaagagcca     3180

gccacacctg cttacacaat aagtgccact gagctgctag aaaagcaggc cacaccaaga     3240

gagcctgagc tgctgtatca aaatattgct gagcgagtca aggaacttcc cagcgcaggc     3300

ctagtccact ataacttttg taccttacct aaaaggcagt ttgccccttc ctatgaatct     3360

cgacgccaaa accaagacag aatcaataaa accgttttat atggaactcc caggaaatgc     3420

tttgtggggc agtcaaaacc caaccaccct ttactgcaag ctaagccgca atcagaaccg     3480

gactacctcg aagttctgga aaaacaaact gcaatcagtc agctgtgaag ggaaatcatt     3540

tacaacccta aggcatcaga ggatgctgct ccgaactgtt ggaaacaagg acattagctt     3600

ttgtgtttgt ttttgttctc cctttcccag tgttaatggg ggactttgaa aatgtttggg     3660

agataggatg aagtcatgat tttgcttttg caagttttcc tttaaattat ttctctctcg     3720

ctctcctccc ctcctttttt tttttttttt ttttttcttt ttcccttctc ttcttaggaa     3780

ccatcagtgg acatgaatgt ttctacaatg catttcttca tagattttgt ttatggtttt     3840

gtttcttttt tcttctttgt ttttcagtgt gggagtggga agaggagatt atagtgactg     3900

aagaaagaat aggcaaactt ttcaaatgaa aatggatatt tagtgtattt tgtagaagat     3960

ctccaaagat cttttgtgac tacaacttct tttgtaaata atgatatatg gtatttccat     4020

cgtcagttac cgagtatagc cactgggtat cactactttg tgttaaagtg ccttcgcact     4080

ttaagtacat tacttaaatg ttgcttttag ctttgataaa ttgaaaatat tttaatgtgt     4140

tgtatttttg aaattgaaaa cactgtaaaa tagattgatg tgtcagctat attaagtcaa     4200

cgtacagttt gcttgagtta tagaaaccag cctgtcatca aatgattcta gttctaggac     4260

tttgtaggct taactataaa atatttcctt tcctctgggt ttaagtgatt ttatttaagt     4320

caactaaggg gatttaacag tggactagag gtaataagcc acctcagtca ggattaataa     4380

ttcattaata aaatatattt aacccaaaaa aaaaaaa                              4417


<210>  862
<211>  17035
<212>  DNA
<213>  homo sapiens

<400>  862
acttagacac ttccagctgg tggcagggga tacagccata atacagcttc ctctgtccca       60

gctgtcttct tcactacggt aaatgcatta cgatggctgc actctcctgt aaaggttcag      120

gtagaggaag gtgtaggatg aagtccggac accatcattt gggtttttaa aagcttcagc      180

ttctccagca tctttgcatt gtgaatatct tcctgcttct agtcaaagct ttctctctag      240

tgattggaat gctgctgtaa gcctgattag aggtgcctga ggatatcacc ttttacaagg      300

aagccgtgtg tgcttgagag gatcttttta aatgcattat ggctcatgca gcctcacaat      360

taaagaaaaa cagggattta gaaatcaatg ctgaagaaga gcctgagaaa aaaaggaaac      420

accgcaaacg gtcccgggat cggaagaaaa agtctgatgc caatgcaagt tacttaagag      480

cagctcgagc tggacacctt gaaaaggccc tcgactacat aaaaaatgga gttgacatca      540

acatttgcaa tcagaatggg ttgaacgctc tccaccttgc ttccaaagaa ggccatgtag      600

aggttgtttc tgagctgctg cagagagaag ccaatgtgga tgcagctaca aagaaaggaa      660

acacagcatt gcacatcgca tctttggctg ggcaagcaga ggtggtaaaa gtcttggtta      720

caaatggagc caatgtcaat gcacaatctc agaatggttt cacgccattg tatatggcag      780

cccaggaaaa tcacctggaa gttgtcaagt ttcttcttga caatggtgca agccagagcc      840

tagccacaga ggatggcttc acaccattgg cagtggcttt gcaacaaggt cacgaccaag      900

tcgtttcgct cctgctagag aatgacacca aaggaaaagt gcgtctccca gctcttcata      960

tcgcggcccg aaaagacgac acgaaagccg ccgccctgct gctgcagaat gacaacaatg     1020

cagatgtgga atcaaagagt ggcttcactc cgctccacat agctgctcac tatggaaata     1080

tcaatgtagc cacgttgctg ttaaaccgag cggctgctgt ggatttcacc gcaaggaatg     1140

acatcactcc tttacatgtt gcatcaaaaa gaggaaatgc aaatatggta aaactattgc     1200

tcgatcgagg agctaaaatc gatgccaaaa ccagggatgg tctgacacca ctgcactgtg     1260

gagcaaggag tggccacgag caggtggtag aaatgttgct tgatcgagct gcccccattc     1320

tttcaaaaac caagaatgga ttatctccat tgcacatggc cacacaaggg gatcatttaa     1380

actgcgtcca gcttctcctc cagcataatg tacccgtgga tgatgtcacc aatgactacc     1440

tgactgccct acacgtggct gcccactgtg gccattacaa agttgccaag gttctcttgg     1500

ataagaaagc taaccccaat gccaaagccc tgaatggctt tacccctctt catattgcct     1560

gcaagaagaa tcgaattaaa gtaatggaac tccttctgaa acacggtgca tccatccaag     1620

ctgtaaccga gtcgggcctt accccaatcc atgttgctgc cttcatgggg catgtaaata     1680

ttgtatcaca actaatgcat catggagcct caccaaacac caccaatgtg agaggagaaa     1740

cagcactgca catggcagct cgctccggcc aagctgaagt tgtgcggtat ctggtacaag     1800

acggagctca ggtagaagct aaagctaagg atgaccaaac accactccac atttcagccc     1860

gactggggaa agcagacata gtacaacagc tgttgcagca aggggcatct ccaaatgcag     1920

ccacaacttc tgggtacacc ccacttcacc tttccgcccg agaggggcat gaggatgtgg     1980

ccgcgttcct tttggatcat ggagcgtctt tatctataac aacaaagaaa ggatttactc     2040

ctcttcatgt ggcagcaaaa tatggaaagc ttgaagtcgc caatctcctg ctacagaaaa     2100

gtgcatctcc agatgctgct gggaagagcg ggctaacacc actgcatgta gctgcacatt     2160

acgataatca gaaagtggcc cttctgcttt tggaccaagg agcctcacct cacgcagccg     2220

caaagaatgg ttatacgcca ctgcacatcg ctgccaaaaa gaaccagatg gacatagcga     2280

caactctgct ggaatatggt gctgatgcca acgcagttac ccggcaagga attgcttccg     2340

tccatctcgc agctcaggaa gggcacgtgg acatggtgtc gctgctcctc ggtagaaatg     2400

cgaatgtgaa cctgagcaat aagagcggcc tgaccccact ccatttggct gctcaagaag     2460

atcgagtgaa tgtggcagaa gtcctcgtaa accaaggggc tcatgtggac gcccagacaa     2520

agatgggata cacaccactg catgtgggct gccactatgg aaatatcaag attgttaatt     2580

tcctgctcca gcattctgca aaagttaatg ccaaaacaaa gaatgggtat acgccattac     2640

atcaagcagc acagcagggg catacgcata taataaatgt cttacttcag aacaacgcct     2700

cccccaatga actcactgtg aatgggaata ctgcccttgg cattgcccgg cgcctcggct     2760

acatctcagt agtggacacc ctgaagatag tgaccgaaga gaccatgacc acaactactg     2820

tcacagagaa gcacaaaatg aatgttccag aaacgatgaa tgaagttctt gatatgtctg     2880

atgatgaagt tcgtaaagcc aatgcccctg aaatgctcag tgatggcgaa tatatctcag     2940

atgttgaaga aggtgaagat gcaatgaccg gggacacaga caaatatctt gggccacagg     3000

accttaagga attgggtgat gattccctgc ctgcagaggg ttacatgggc tttagtctcg     3060

gagcgcgttc tgccagcctc cgctccttca gttcggatag gtcttacacc ttgaacagaa     3120

gctcctatgc acgggacagc atgatgattg aagaactcct tgtgccatcc aaagagcagc     3180

atctaacatt cacaagggaa tttgattcag attctcttag acattacagc tgggctgcag     3240

acaccttaga caatgtcaat cttgtttcaa gccccattca ttctgggttt ctggttagct     3300

ttatggtgga cgcgagaggg ggctccatga gaggaagccg tcatcacggg atgagaatca     3360

tcattcctcc acgcaagtgt acggccccca ctcgaatcac ctgccgtttg gtaaagagac     3420

ataaactggc caacccaccc cccatggtgg aaggagaggg attagccagt aggctggtag     3480

aaatgggtcc tgcaggggca caatttttag gccctgtcat agtggaaatc cctcactttg     3540

ggtccatgag aggaaaagag agagaactca ttgttcttcg aagtgaaaat ggtgaaactt     3600

ggaaggagca tcagtttgac agcaaaaatg aagatttaac cgagttactt aatggcatgg     3660

atgaagaact tgatagccca gaagagttag ggaaaaagcg tatctgcagg attatcacga     3720

aagatttccc ccagtatttt gcagtggttt cccggattaa gcaggaaagc aaccagattg     3780

gtcctgaagg tggaattctg agcagcacca cagtgcccct tgttcaagca tctttcccag     3840

agggtgccct aactaaaaga attcgagtgg gcctccaggc ccagcctgtt ccagatgaaa     3900

ttgtgaaaaa gatccttgga aacaaagcaa cttttagccc aattgtcact gtggaaccaa     3960

gaagacggaa attccataaa ccaatcacaa tgaccattcc ggtgcccccg ccctcaggag     4020

aaggtgtatc caatggatac aaaggggaca ctacacccaa tctgcgtctt ctctgtagca     4080

ttacaggggg cacttcgcct gctcagtggg aagacatcac aggaacaact cctttgacgt     4140

ttataaaaga ttgtgtctcc tttacaacca atgtttcagc cagattttgg cttgcagact     4200

gccatcaagt tttagaaact gtggggttag ccacgcaact gtacagagaa ttgatatgtg     4260

ttccatatat ggccaagttt gttgtttttg ccaaaatgaa tgatcccgta gaatcttcct     4320

tgcgatgttt ctgcatgaca gatgacaaag tggacaaaac tttagagcaa caagagaatt     4380

ttgaggaagt cgcaagaagc aaagatattg aggttctgga aggaaaacct atttatgttg     4440

attgttatgg aaatttggcc ccacttacca aaggaggaca gcaacttgtt tttaactttt     4500

attctttcaa agaaaataga ctgccatttt ccatcaagat tagagacacc agccaagagc     4560

cctgtggtcg tctgtctttt ctgaaagaac caaagacaac aaaaggactg cctcaaacag     4620

cggtttgcaa cttaaatatc actctgccag cacataaaaa ggagacagag tcagatcaag     4680

atgatgagat tgagaaaaca gatagacgac agagcttcgc atccttagct ttacgtaagc     4740

gctacagcta cttgactgag cctggaatga ttgaacggag tacaggagca acaagatccc     4800

tccccaccac ttactcatac aagccattct tttctacaag accataccag tcctggacaa     4860

cagctccgat tacagtgcct gggccagcca agtcaggctt cacttcctta tcaagttctt     4920

cctctaatac gccatcagct tctccgttaa aatcaatatg gtctgtttcg acaccttctc     4980

caatcaaatc cacattaggc gcgtcaacta catcttcagt taaatccatt agtgacgtgg     5040

catctccaat tagatccttt cggacaatgt cttcgccgat aaaaactgtg gtgtcacaat     5100

ctccatacaa tatccaagtt tcctctggta ccctggctag agctccagca gtcacggaag     5160

ctacgccctt aaaagggctg gcatccaatt ctacgttttc ctctcgaacc tctccagtga     5220

ctacagcagg gtctcttttg gagaggtcat caattactat gacaccccct gcctccccca     5280

aatcaaacat taatatgtat tcctcaagtt tgccatttaa gtcaattatt acatcagcag     5340

caccgctaat atcttcacct ttaaagtcag tggtgtctcc agttaaatca gcagttgatg     5400

tcatttcatc agccaaaatt acaatggcat cttctctctc atcacctgtg aagcagatgc     5460

ctggacatgc agaggtagca ttagtcaatg gatctatttc ccctctaaaa tatccatcat     5520

cctcaacttt aattaatgga tgcaaagcca ctgccacgtt acaggaaaaa atttcttctg     5580

ctacaaactc tgtgagctct gtggtcagtg cagccactga cacagttgag aaagtgtttt     5640

ctaccacgac tgcaatgcca ttttccccac tcaggtcata tgtttctgca gcaccatcag     5700

cttttcagtc tctaagaact ccttccgcaa gtgcactcta tacatccctt gggtcgtcaa     5760

tatctgcaac tacctcatct gtaacttcat caattataac agtgccagta tactctgtag     5820

tcaatgtttt gccagaacca gcattaaaga aacttccaga ctctaattca tttacaaaat     5880

cagcagcagc cttgctgtca cccattaaaa cattgactac ggagacacat cctcagcctc     5940

acttcagtcg aacttcatct ccagttaagt catctttgtt ccttgcaccc tctgccctta     6000

agttgtctac accatcttct ttatcttcca gtcaggagat actaaaagat gtagctgaaa     6060

tgaaagagga cctaatgcgg atgaccgcaa tactacagac agatgtgcct gaggagaagc     6120

cattccaacc tgaactccca aaggaaggga gaatagatga tgaagaacct ttcaaaattg     6180

tagagaaagt aaaggaagac ttagtgaaag ttagtgaaat ccttaaaaag gatgtatgtg     6240

tagataataa aggatcaccc aaatcaccaa agagtgacaa aggacactct cctgaagatg     6300

actggataga atttagttcg gaagaaatcc gggaagccag acaacaagct gctgcgagcc     6360

agtctccatc tctgccagag agagtgcaag taaaagcaaa agccgcctcc gaaaaggatt     6420

ataacttgac caaagttatt gattacctaa caaatgatat tgggagtagt tcactgacaa     6480

acttaaaata caagtttgag gatgcaaaga aggatggtga ggagagacag aaaagagttt     6540

taaaaccagc aattgctttg caggaacaca aactcaaaat gcctccagcc tccatgagga     6600

cttccacctc tgagaaagaa ttgtgtaaaa tggctgattc cttttttgga acagatacta     6660

ttttagagtc tcctgatgac ttttctcaac acgaccaaga taaaagtccc ttgtctgaca     6720

gtggctttga aacaagaagt gaaaagacac cttcagcccc acaaagcgct gaaagcactg     6780

gtcctaaacc actttttcat gaagttccca tccctcctgt cattacagaa acaagaactg     6840

aagtggttca tgttatcagg agctatgatc cctcagctgg ggatgttccc cagacccaac     6900

cagaggagcc tgtgtcacct aaaccttcac ctacttttat ggaattggaa ccaaagccca     6960

ccacctctag tattaaagaa aaggttaaag catttcaaat gaaagccagt agtgaagaag     7020

atgaccacaa tcgggtttta agcaaaggca tgcgtgttaa agaagagact cacataacca     7080

caaccaccag aatggtttat cattctccac caggcggtga aggtgcatct gaaagaattg     7140

aagaaaccat gtcagtccat gacatcatga aggcctttca gtccgggcgg gatccttcca     7200

aagaactggc aggtctgttt gaacataagt cggcagtgtc tccagatgtt cacaagtctg     7260

ctgctgaaac ctcagcccag catgcagaga aggacaacca aatgaaaccc aaactggagc     7320

gtataataga agtccacatc gaaaaaggta accaagctga gcccactgaa gtcattatta     7380

gagaaaccaa aaagcatcca gaaaaagaaa tgtatgtata tcagaaagac ttatcccggg     7440

gagatattaa cctaaaagat tttctgccag aaaaacacga tgcttttcct tgttcagagg     7500

aacagggtca gcaagaagaa gaagaactta ctgctgaaga gtcattgcct tcttatctgg     7560

agtcttccag agtaaacact cctgtgtccc aagaagaaga tagccgccct agttctgctc     7620

aactcatatc tgatgactct tataaaacat tgaagctttt gagtcaacac tcaatagaat     7680

accatgacga tgagttgtca gaactaagag gggagtctta caggtttgct gagaaaatgc     7740

ttctgtcaga aaagctagat gtgtctcatt ctgatactga ggaatcggtt acagaccatg     7800

caggaccccc tagctcagag ttacaggggt ctgataagcg gtccagagaa aaaatagcca     7860

ctgcccccaa aaaagaaatt ctctccaaaa tctataaaga tgtttctgaa aatggtgtag     7920

gtaaagtgtc taaagatgag cattttgata aagtgacagt gttgcactat tctggcaatg     7980

ttagtagtcc aaaacatgcc atgtggatgc gctttactga ggacagatta gacagaggta     8040

gagagaagtt gatatatgaa gatagggtgg acaggactgt gaaggaggct gaagaaaaac     8100

tgactgaagt gtcacagttt tttcgtgaca aaactgaaaa gctaaatgat gaactgcagt     8160

ccccagagaa aaaggcacgc cctaaaaatg gcaaagaata ttcttctcaa agccctacca     8220

gtagcagccc tgagaaagtg ctactgacag aactgctggc atccaatgat gagtgggtta     8280

aggcaagaca gcatggccct gatggacaag gcttccccaa ggccgaggag aaggcaccca     8340

gtctgcccag cagcccagag aagatggttc tctcccaaca gactgaggac agcaagtcca     8400

cagtggaagc caaaggaagt atttcacaga gcaaagcacc agatgggccc cagtctggat     8460

tccagctcaa acaatctaaa ctcagttcca ttagattaaa atttgaacaa ggcacacacg     8520

caaaaagtaa ggacatgtct caagaagaca gaaagtcaga tggccagtcc agaatcccag     8580

ttaaaaaaat acaggagagc aagctacccg tctaccaagt ttttgctaga gaaaaacagc     8640

agaaggccat agacctccca gatgaaagtg tatctgtgca aaaagatttt atggtattaa     8700

aaaccaaaga tgagcatgcc caaagcaacg aaattgttgt aaatgattct ggctctgata     8760

atgtgaaaaa acagagaact gaaatgtcaa gtaaagcaat gcctgactct ttttctgagc     8820

agcaggctaa agacttggca tgtcatataa cctcagattt agcaactagg ggaccatggg     8880

acaaaaaggt ctttagaaca tgggagagtt cgggagccac taacaataag tctcagaaag     8940

aaaaactttc gcatgtactt gttcatgatg taagagagaa tcacattggt caccctgaga     9000

gtaaaagtgt tgatcaaaag aatgaattta tgtctgtgac tgagagagaa cgcaaattgt     9060

taacaaacgg ctctctctca gaaattaaag aaatgactgt aaaatctccc tccaaaaaag     9120

tcttatatag ggaatatgtt gtgaaagaag gggaccatcc aggcggattg cttgatcagc     9180

cttccaggag gagcgagagc tcagcagtgt cacacattcc cgtcagagtt gctgatgaga     9240

ggagaatgct gtcttctaat attcccgatg gtttttgtga acagtcggca tttccaaaac     9300

atgaactatc acaaaaattg tcccagtcaa gcatgagtaa agagacagtt gagacacagc     9360

actttaattc tatagaagat gaaaaagtta cctattcaga aatcagcaaa gtttccaaac     9420

accagagtta tgtaggttta tgcccacctc tcgaggaaac cgaaacctcc cccaccaaat     9480

ctcctgattc tttagagttt agcccaggaa aggaatctcc ctctagtgat gtattcgacc     9540

acagtcccat tgatggattg gaaaaactcg caccactagc ccagacagag ggagggaaag     9600

agataaaaac tttacccgtt tatgtcagtt ttgtacaagt ggggaagcaa tatgaaaagg     9660

agatacaaca aggaggtgta aaaaaaatca taagtcagga atgtaagaca gtacaagaaa     9720

ccagggggac cttttataca actagacagc aaaagcaacc tccttctccc caaggtagtc     9780

cagaagatga tactctagag caagtatcct ttctagacag ctctgggaaa agccctttaa     9840

ccccagaaac acccagttca gaggaagtga gttatgaatt tacatctaag acacctgact     9900

cgctcatagc ttatatacca ggcaaaccca gcccaattcc cgaggtttct gaggagtcag     9960

aggaggagga acaggccaag tcaacctccc ttaagcagac tacagtggag gaaacagcag    10020

ttgagcgtga aatgcctaat gacgtgagca aagactctaa ccaaagaccc aaaaataaca    10080

gagttgccta tattgaattt ccccctcctc caccactgga tgcggaccag attgagtcag    10140

ataagaagca tcattatctc ccagaaaaag aggttgacat gattgaagtc aatctgcaag    10200

atgagcatga caagtaccag ctggctgaac ctgtcattag agtgcagcca ccttcaccag    10260

ttcctcccgg ggcagacgtc agtgattcaa gcgatgacga atctatttat cagccagtcc    10320

cagttaaaaa atataccttc aaattaaagg aagtggacga tgaacaaaaa gaaaaaccca    10380

aagcttctgc tgaaaaggct tccaaccaga aagaactgga aagtaatgga tctggaaaag    10440

ataatgaatt tggccttggc cttgattcac ctcagaatga aattgcccag aatgggaaca    10500

acgaccagtc catcacagag tgttccattg ccaccacagc agagttttct catgacacgg    10560

atgccacaga gatcgactct ctggatggct atgacctgca agatgaagat gatggcttga    10620

cagagagtga ttctaaactc ccaattcaag ccatggaaat taagaaagat atctggaaca    10680

cagagggcat tctgaagcca gctgaccgct cttttagcca aagtaaactt gaagttatcg    10740

aggaggaggg aaaggtggga ccagatgagg acaagccacc ttctaaaagt tcttcatctg    10800

aaaagactcc tgataagact gatcagaagt caggggccca gttcttcaca ctggaaggca    10860

gacatcctga cagatcagtg tttcctgata cttacttcag ttacaaagta gatgaagaat    10920

ttgccactcc ttttaaaaca gtagctacca aaggtctaga ttttgaccct tggtctaata    10980

accgagggga tgatgaagtt tttgacagta aatcacggga agatgaaact aagccatttg    11040

ggctggcggt agaagaccgc tctccagcaa caacccctga tacaacgcca gccagaacgc    11100

caactgatga aagtacccca actagtgagc ctaacccctt cccatttcat gaaggaaaaa    11160

tgtttgagat gactcgcagt ggtgcaattg acatgagcaa gagggatttt gttgaagaga    11220

ggctccaatt tttccagatt ggtgagcata cttctgaagg gaagtcaggg gaccaggggg    11280

aaggggataa aagtatggtc actgccacac cacagccaca gtcaggggac accactgtag    11340

aaaccaatct agagagaaat gtagagacac ctacagtgga acctaacccc agcatcccga    11400

ccagcggaga gtgtcaggaa ggcacatcca gtagtggctc cctggagaaa tcagcagcag    11460

ccactaacac ctctaaagtt gaccccaagt tgcgcacgcc tataaaaatg ggaatttctg    11520

catccaccat gaccatgaag aaagaaggcc ctggagaaat aacagataag atagaagcgg    11580

tgatgaccag ttgtcaggga ttagaaaatg aaactataac aatgatttca aatacagcca    11640

atagccagat gggcgttagg ccccatgaaa aacatgattt tcaaaaagat aactttaata    11700

acaacaacaa tttggattct tccactatac agacagataa cattatgagt aatatagttc    11760

tgacagaaca ttctgcaccc acttgtacca cagagaaaga taacccagtg aaagtctcat    11820

caggaaaaaa gacaggggta ctacaaggac actgtgtaag agataagcag aaagttcttg    11880

gagaacagca aaaaacaaag gaattgatag ggattaggca aaaatccaaa cttcccataa    11940

aggccacttc accaaaagat accttcccac cgaaccatat gtcaaacact aaagcaagta    12000

aaatgaagca ggttagtcaa tccgagaaaa ccaaagccct tactacttct tcatgtgtag    12060

atgtaaagtc cagaattcca gtgaaaaaca cacacaggga taacataatt gcagttagaa    12120

aagcatgtgc cacacaaaag caagggcagc cagagaaagg caaggccaaa cagcttccat    12180

ccaagttgcc agtaaaggta agatccacct gtgtcactac caccaccacc actgccacca    12240

ccaccaccac taccaccact accaccacca ccagctgcac agttaaagtt aggaaaagtc    12300

agctcaagga agtatgtaaa cattccattg aatattttaa gggaattagt ggtgagacct    12360

taaagcttgt ggaccgcctc tctgaagaag aaaaaaagat gcagtccgag ttgtccgatg    12420

aggaagaaag tacctcaaga aacacgtcgt tgtccgagac ttcccggggt ggccagcctt    12480

cggttacaac gaagtctgct agagataaga aaacagaggc agcaccttta aaatcaaaga    12540

gtgaaaaggc cggcagtgag aaaaggagca gtagaaggac tggtccacag agtccatgtg    12600

aacggacaga tatcaggatg gcaatagtag ccgatcacct gggacttagt tggacagaac    12660

tggcaaggga actgaatttt tcagtggatg aaatcaatca aatacgtgtg gaaaatccaa    12720

attctttaat ttctcagagc ttcatgttat taaaaaaatg ggttaccaga gacggaaaaa    12780

atgccacaac tgatgcctta acttcggtct tgacaaaaat taatcgaata gatatagtga    12840

cactgctaga aggaccaata tttgattatg gaaatatttc aggcaccaga agttttgcag    12900

atgagaacaa tgttttccat gaccctgttg atggttggca gaatgagaca tcaagtggaa    12960

acctagagtc ctgcgctcaa gctcgaagag taactggtgg gttactagat cgactggatg    13020

acagccctga ccagtgtaga gattccatta cctcatatct caaaggagaa gctggcaaat    13080

ttgaagcaaa tggaagccat acagaaatca ctccagaagc aaagacaaaa tcttactttc    13140

cagaatccca aaatgatgta ggaaaacaga gtaccaagga aactctgaaa ccaaaaatac    13200

atggatctgg tcatgttgaa gaaccagcat caccactagc agcatatcag aaatctctag    13260

aagaaaccag caagcttata atagaagaga ctaaaccctg tgtgcctgtc agtatgaaaa    13320

agatgagtag gacttctcca gcagatggca agccaaggct tagcctccat gaagaagagg    13380

ggtccagtgg gtctgagcaa aagcagggag aaggttttaa ggtgaaaacg aagaaagaaa    13440

tccggcatgt ggaaaagaag agccactcgt aacagcgaac ggtcagtcaa ggatcataag    13500

tttttactgc cagtattgag aaattcgtgg aagaaatgtc agcaggaagt aaaaattcac    13560

cgagaagtgt gtgtgtgttc gctgcttcca cacattaatg gcatgatttt ttttatgcaa    13620

aaagaaaaga aaagaaaacc acccacattt taatttagca tgagccaatt tacagagcat    13680

ggaaatcact ttcatttccg gattggcgcg tgtgcaatta gcaatgcagt gtatatacaa    13740

gaagccatgc tgttaacagt ttatctcaag taatttggtg tcatttacaa aaggaagaaa    13800

ttcctgccat cagaagggac agaaggagat ggaatgatca aatcacagag aaacactaaa    13860

attactaaat ctacaacagc tcgccttatt tttcttggac ccaaactgtc agggtataaa    13920

cactatttgt ttctttttta aaacatcgat agttttgctg taaataataa cactgtataa    13980

attctaacag aaaaatagaa taaaatgttg ataaggcact gcctcttaga acacaaacag    14040

aatattgcaa atgcatttaa caaatagggg tctcaagtga cttcacccta gaagaggagg    14100

gagggattct gggtgggggt gactcttcac tgattcttgt atattagcaa ttataatgtt    14160

tgtatatgca aaactgctag cttgatttta aaaaaaaaca aatctttaaa atctgctgca    14220

aatttaaata attcccaaaa tgaggaattc tgtagttctg tgaaaaattt ttttcttcag    14280

aatactaata ttttgatgca tgtgtatcac cttattttga ttaaatcttt tccaattttg    14340

caaacactac agtatactgc aacacaaaag attttatctg taaacacaaa gcccttcatc    14400

taatatttgt tgctattgcc aatttttcaa tgaaatgacc taaaaacaac aaaaaaaaat    14460

aacctatacg gtagttgctt tagggggtgg ggggatgcta tctgttagtg cttaaaaggg    14520

ggtaaatgct tgccgcttta gaggtggatg gtgctcataa aaggccccag tcgggggtat    14580

ttaaaaagga ctgaacagaa atccttagct agtagaatgg cagcacgctg taaaattatt    14640

actgtattgt gtactggcta taagatgtag acacctttca gtaagccaat catttgtaac    14700

cattctagca gtgtcatatt aggttaataa ggctgctgtg ttttaaaggg catttttatt    14760

tgggttttgg tgaaattctt taatttgttg attatattca cataaaatca gcattcattg    14820

acacatagct ctaatgacat atgtatgaaa aaccatacac tggatgacct agtcgattat    14880

ttaagcataa aataaattgt gttaaactct tcacctatct gtgctctaca gtctccttgt    14940

gttttctggc aaaaggtagt tgtctaatcc cttgtcatat gagtcctggc caatccaccc    15000

cattggtcct ctttgtgcct ctgtggtcac tgaagagata atctctaaca ttcatatgtg    15060

ccctgcaagc tcccagctta taaattctgt gcatttcatg ggggagccaa gaattaaaga    15120

ttaattgaca agtaagcttt gcccacatct gttcaggcct tcttgaaaag tgaagaattg    15180

gagatactat agccagcatg tcaaaaagtt gactggcact tctaggaacc atcaacatgc    15240

agttgctttt agcccacaga gcttgttttt gttttgtttt attaatttac atttattgtc    15300

cattcttaca agttgggaca tttcacataa ttaagttgct aacatctctt aaaaagcaag    15360

atttggcaac aatggacctc attcccagaa ggtaacaacc tgctagagcc aagttgtccc    15420

tgccctctcc agccaggtgt ggggtctaca ggtatcactg ccacagcctc atttcttata    15480

tttgtacaac ctgactgtga atttgcaacc catacactgc gtgaatctaa attctactga    15540

ggcagagacc atggctgttt taacttttat tctagttacc agcttagcat atggtagtag    15600

tgatagtagt aactgtgatc atcatcacta aaactggagt gctcactaca tgctattctc    15660

tgttctaagc acattccatt tacttactta gtcctcatat ctactttatg aattaggtac    15720

tgtctttctt tgatggtaat gatcctttta taaaattaaa ttagtgctaa gagactttca    15780

gcaatgttat atattgcctg tccattaaag attgttgcca aatggagtga gttgtcccca    15840

gtaaggattc actatcaatg cagaagaaat gcacggataa tctactttgc ataaagaatg    15900

gggctaggtt gcatctgcat ggtatcccaa ataaataaaa tgtgccacta cccttgcacc    15960

aaaattattt tatgatgggt aaagttagac ccttgagagg tttttttttt aaaaaaaaaa    16020

aaaaaaaaaa actttcccaa aatgcctctc tgtaaagcca ggatcagaat ataggtgtcc    16080

taacttccta tctaagagtt acgaatttct gactcagtct ttgagagaag gtgtttatcc    16140

tgaaccagaa actcaatgat gtatacctgt ttaggtatta aatagttgtg tttatatgcc    16200

caaaaatttg actttaggta tatgtgatat gctttggttc cgatcaagca ggaggtcata    16260

agtttactca gaagtatcca aaatatgaca ttcaagattt aacttgcata tgtgtgtata    16320

tgcatatatt tatacatgta tatgtagatt gaatgtgaca ttatgtattt ctaacataat    16380

atttggcctg ccagcttata aatatgtatt taagcttttc attgattgac attactgtaa    16440

aaaatgaatt atgattgaga agttctggat atttgctgtt tttttcattt tatattctta    16500

ctaaattatt gaatttgtta aattaaaatg tgctatcact gtattgccaa attatggcaa    16560

tacactatgc agtattattt caatacttta agaggcatct attacttcat tgaacacata    16620

agcagctagc ctcctttcct ctgtaaataa ggactttttg gcatcctgat gttcctcgct    16680

gttcatttgg tatcatcctg gagttccatc aagactgagg attttctcca tggccaataa    16740

actattgtca gcatcagctc acgtttggct gtatgacagg gatatgtgag aagcccagaa    16800

ataaatcaca aaaataataa ggcatcttct gagtctctct gaagaagcca gtgatccaaa    16860

aactaacttc atatctgagt gagtcttggt attcttgatt tgcttgaaga ggctgtgaca    16920

tattacaagg tgtgtaattt cccaggcata tcacactgct tctgtttcat gaattgatca    16980

aattgtccag aagtaaacat ttacaagatt gagatttgaa aaaaaaaaaa aaaaa         17035


<210>  863
<211>  6904
<212>  DNA
<213>  homo sapiens

<400>  863
ggcccccaga gagggtgggg agatgacaca gttgttcccc cagccctggc ggggcgggca       60

gcatggttca ctccagcatg ggggctccag aaataagaat gtctaagccc ctggaggccg      120

agaagcaagg tctggactcc ccatcagagc acacagacac cgaaagaaat ggaccagaca      180

ctaatcatca gaacccccaa aataagacct ccccattctc cgtgtcccca actggcccca      240

gtacaaagat caaggctgaa gaccccagtg gcgattcagc cccagcagca cccctgcccc      300

ctcagccggc ccagcctcat ctgccccagg cccaactcat gttgacgggc agccagctag      360

ctggggacat acagcagctc ctccagctcc agcagctggt gcttgtgcca ggccaccacc      420

tccagccacc tgctcagttc ctgctaccgc aggcccagca gagccagcca ggcctgctac      480

cgacaccaaa tctattccag ctacctcagc aaacccaggg agctcttctg acctcccagc      540

cccgggccgg gcttcccaca cagcccccca aatgcttgga gccaccatcc caccccgagg      600

agcccagtga tctggaggag ctggagcaat tcgcccgcac cttcaagcaa cgccgcatca      660

agctgggctt cacgcagggt gatgtgggcc tggccatggg caagctctac ggcaacgact      720

tcagccagac gaccatttcc cgcttcgagg ccctcaacct gagcttcaag aacatgtgca      780

aactcaagcc cctcctggag aagtggctca acgatgcaga gactatgtct gtggactcaa      840

gcctgcccag ccccaaccag ctgagcagcc ccagcctggg tttcgacggc ctgcccggcc      900

ggagacgcaa gaagaggacc agcatcgaga caaacgtccg cttcgcctta gagaagagtt      960

ttctagcgaa ccagaagcct acctcagagg agatcctgct gatcgccgag cagctgcaca     1020

tggagaagga agtgatccgc gtctggttct gcaaccggcg ccagaaggag aaacgcatca     1080

acccctgcag tgcggccccc atgctgccca gcccagggaa gccggccagc tacagccccc     1140

atatggtcac accccaaggg ggcgcgggga ccttaccgtt gtcccaagct tccagcagtc     1200

tgagcacaac agttactacc ttatcctcag ctgtggggac gctccacccc agccggacag     1260

ctggaggggg tgggggcggg ggcggggctg cgccccccct caattccatc ccctctgtca     1320

ctcccccacc cccggccacc accaacagca caaaccccag ccctcaaggc agccactcgg     1380

ctatcggctt gtcaggcctg aaccccagca cgggccctgg cctctggtgg aaccctgccc     1440

cttaccagcc ttgatggcag cgggaatctg gtgctggggg cagccggtgc agccccgggg     1500

agccctggcc tggtgacctc gccgctcttc ttgaatcatg ctgggctgcc cctgctcagc     1560

accccgcctg gtgtgggcct ggtctcagca gcggctgcgg ctgtggcagc ctccatctcc     1620

agcaagtctc ctggcctctc ctcctcatcc tcttcatcct catcctcctc ctcctccact     1680

tgcagcgaga cggcagcaca gacccctgga ggtccagggg ggcccgaggc agggtccaaa     1740

cctgagtgag ggccagccat gcctcccctc ccattcctct ggtccctgcc ttggtccctt     1800

gcctgggaag agggcgagga ggccagtggt ggggacgcag agggtcctca gagcaggagt     1860

gacaagggag gaaagaccaa aaaaacaacc aaccaaaaaa aaaaaaaaaa aggaaagaaa     1920

ctaaccaaca aaagagaaaa ccaaaaataa tcacaacaga aaccagctgc cccaaaggaa     1980

ccagaggtga aaaacaaaca aaaaaaaacc aaaaacaaac caaaaaaaaa aaaaacccac     2040

aaaatcaaac aaaccaaaaa accagtcgcg agccagacct cagcgtgctc accctcactg     2100

ctacgacgcc aaataaaaac cccagccagg ggcggagaag cctccagcag gtcagacctc     2160

atgccaccga gccctggctg tgggaccaac ccccaaccct gcctcccccg tgggggctac     2220

agaaggaaaa agagaagatg ccagcttcct aatcccagcc cccagccctg ggccagcgaa     2280

gacagggcac agcctgggca gatgggctgg ggcttagcac cacccaccaa atgttctttt     2340

ccagaaggtg aaagagaaag ggcctgaaca accttacacc aaatattcag tagcttcatc     2400

caaaggatgt acagaatttt tagcattgtg ctcaacagaa tgtgtcccta ccatgtgtcc     2460

ccttctcccc tggcccccag ctctccccac ctgggcaggg ggtcttgctt taacctcctc     2520

cctcccccca gcaggggaga gttcaaggga aggcctgcgg acaacttttc atcccctgtt     2580

cctccctctt ttcccctttg aagggtgggc taggccattt tgccaagttc tagctctcac     2640

aagtccctcc tcaaccctgt caccctcctc tgctctggaa ctgactccct ccccagccta     2700

tgggaaggtg gaaatttcag gcaagagggg atgaagacat tcagttgagg gcattcagtt     2760

gtctttttcc atcctgtctg tttccctgaa aaaaaaaaaa attcatattc cagtgcctat     2820

ccgtgggatc cttcacgttc tttgacatta accagaaacc aaaaagagaa ctcacctcgc     2880

ttttcccacc ctgtgcccct ctggtactgg cgaatgcctc tccctccccc cacatgcacg     2940

cacgcacaca ccccagtggt ggggttcctc gagatggcat ccccatcagg gtccatgtgg     3000

tggggacagt gccacagcct gtggtcccca tctgagaggg cgcggtggtg gccaccactc     3060

ccacaagacc tccacaactc ttggctggac cctgtgtttg accagccccg gacacgtctc     3120

cactgacgac ggacagagga gagacaccac tgggagccac cctgccctcc tgctattgtg     3180

gaggccaaca aagttttgaa ccgaaaacca aaaaaacaga aacaaacaaa caataaattt     3240

aaactagaaa aaaaatttat atatatatat aaacatatat atatatatat atataaaagg     3300

gaaagaagat gaggactctt caagaataag atggaaccgc gaggcggagc caagcccctg     3360

caccggtggt ccaggccctt gttccccaag gcggatggaa ggacggatgc ttctttctct     3420

tcacaaatac ctcatggacg ttgtctttgg gaaagccgga gggggcggct ggggcagggc     3480

ctgtccctcg gccagggcag atggaagcgg gtgggcgggg ctgagagagg gtatcaggga     3540

caggggtgaa gagccccaaa ctcccctccc aaatcaactg aaaaagcttt aaaaaaagac     3600

aggaaaaaaa ggagtaagaa agcaaaaaga acagatgaag gaaaacttaa caacttttgg     3660

gtggtttgat tcctcctttg atttcttttt cggttctctt ttgtctgacc tctctcctcc     3720

cctccttcct ctctcctccc ctccttcctc tctcctctcc tccttcctgt ctcctctctc     3780

tccctttgct ctcctctctt ctctctcaat cttgttcttt ctgtgtctct cctcaaacca     3840

aagtgttgca gtgaaggaca cgagccattg aaatcagggt ggggcctgac agccgtagtg     3900

tggcccctgc cccttgttgg gcaggagcag agagagagga gagccctgag accgcagggc     3960

tttggcctgg gcagcttcca ctttctgccg gacactctga ggagaggcag atggagctcc     4020

aggcctcagc gttctctttt ttccttgtct cccttctccc acccgggaaa tgaaactgtt     4080

gggctgggcg acggaggcag cagagactcg gccattgcag gggcctctgg gtgccttgtc     4140

cgggcagtgg tgaagtagcc gcccctccca ccccggcacg atggggcctg gcacctcgtc     4200

tacccaacct caccggaatg taagcatctc cgctgaacga ctccctgccc ttaccctacc     4260

tctgagtttg tccatgttta tttcctgaag agagaaggga ctggcaagag ggcttgggcc     4320

ccagcccaag ggtggagagg gggccaaggg ctcctgacca aataggaagg acatttgagc     4380

agagcaaaat gaaaggaatt acaaccaaaa accccctccg agaagacagg cagcatggaa     4440

ggcatggtgg agatgactca aacaaaaact atgattctag accaaaaagg aaaaaaaaaa     4500

aaaaaaaagg aaagaaaatc caggactcac caccacccac ttcatcctgc ttcctcccca     4560

tcaagtccca ccacctggga cctctcccca ccccagtatg tgggagtggg gtaaagagga     4620

gaggaggagc agggggcagg gatggggcag atgccctgat gttggtggag ggacccctgt     4680

gcagccgggg gtgctgggga ccctccccat ccaaccctca cacctaggaa aagaaaaaca     4740

agaaaaaaaa attcctggga gggggaaaaa taaccaaatc ccaagcttta actacagctg     4800

tgaaaccaaa tattgggaag ggggtaggag ggagggaggg gcaggtgagc cccaggtctc     4860

cccctgggcc cccctcccct gaggactcga gataaggcac caaatacctc atagaacttt     4920

aatgttaaaa aaaggaaacc aaatatcgtt ggctgggggc cagccagggc aaggggctgg     4980

ggggctggag ggagccaggg ttgggaaggt gatgggggaa ttcatgcccc ccacccccat     5040

ctgcccctta cactctggtc ccccgtctcg actccgggaa acaaaactat ctcatcgttt     5100

ttattttgtg gtctgtacag agcctgtgtc cgtgtgtctg tgtatgagcg agagagttgg     5160

agggctgggg agctttatgt gggggatggg gagggcaacc ccaggctagg ctatgggcta     5220

ggttagatgt ccgaggttgg gggccaaggg cctgggctag aaagagagga gagatgagtg     5280

ggttggagca gtggggagcc ctctgaattt ctcttctccc caaccctgac ctcctactta     5340

agggagggac agagactggg tctaccctaa tggtgggcct tttcattgtg ccaaaaaaaa     5400

aaaaaaaaaa attgatgcca gtaactaaac cacctctctc tgttctcttc tggggggtgg     5460

ggtgggtgtg tgtgtggggg tgggtaggga tggggaaccc aagccccagt aggagttggg     5520

gctgagatca ggaggagggg aaggatatga gttttccatc catctccctg gagaaggcca     5580

tgacgggctc tccaagccct ggggagatct ggcgagggac tagccaagtc agggtgacct     5640

cttgacctga ctagtttttc taacccacat gaacaccagg gtgcctctct cttcctctag     5700

cccagggtag ggggacctga gtgagagaga gagtgagaca gacagcaaga ttgagacacg     5760

cgggccccca ctggtctctg agtgggaaag gcaagtgcga gagataaagg cctccaagag     5820

aaaaaagaaa caaaccaaag atttaaccat ttaaaaaaaa aaaaaaaccc acagacaact     5880

ccgctacctt tttatatgtt ggaaaaaaag tgaaaaaaaa ttaaaaataa aaataaaaaa     5940

aaatacacaa aaactccaag ccgcaagtcc ttcatgcggt ttaaactttg acctcagcag     6000

tctccaaagc aagacgacga tgacaaaggc ggaaacaaag aaaaaataat gtatattttt     6060

aagtatttgt ccttgaattg ttagctcctt gttaaacaaa caaaaggaga gaaaaatcca     6120

gagagaagtg ttgctgggat ggagacaact atttactatg tctgtgaccc ctcccttctg     6180

cctccctccc cttcctctct ttcctgtcct ctatccttgc tgcccctccc ccaatatgtc     6240

ccccaaaccc aggggctcag tatttattta tttatataat tgcagggtga ctgggggcct     6300

ctctcggcaa ctcgtagaga gcctttggat aatggcaggg tggggaatgg gcgaggagtc     6360

tttgggaaga gcaggggcct gaactttcaa ctcctttctg gcctcttgtc ccactgcttc     6420

caccatcacc ttccaaatcc agggctgcac tagggcaagg tgaccaccct acttggtaaa     6480

gacctgattg gcgcagccca ttctggtgtg ggtgtctttc accacccaga atgaccaggt     6540

tggaatgggg gtgggtgaag ttggaggggg tggcaagtac aaggcaaggg tgcccaggaa     6600

ccggcatcca gaaatcagcc ctggagtaga cctgcctttc ctccatcctt accaagttag     6660

cctccctttc agttccgtct gacccctgtg ttggtagccc cttccttccc ttcctgtacc     6720

ccctccgtct cttctcgtgg tagcgggtta gtgtttcagt gttcttaact ccaatctgct     6780

tgttcattgt acaatgtgct tcttttaagg ccccattttt gtaacttgag tgtgtcattc     6840

atctgaacaa caaacatcaa aaaataaaaa attaaaaact gtacagagag aaatgaaaaa     6900

aaaa                                                                  6904


<210>  864
<211>  1699
<212>  DNA
<213>  homo sapiens

<400>  864
ggccctccct ggaggagaac tgaaacttag ggtggggact gtagaaaggg gcggagagat       60

cagccgccca gccaggagtt aagctgaggt cgtctgagcc ctgcgacagc ctggacagca      120

actcaggatg gcatcaggca gggcacgctg cacccgaaaa ctccggaact gggtggtgga      180

gcaagtggag agtgggcagt ttcccggagt gtgctgggat gatacagcta agaccatgtt      240

ccggattccc tggaaacatg caggcaagca ggacttccgg gaggaccagg atgctgcctt      300

cttcaaggcc tgggcaatat ttaagggaaa gtataaggag ggggacacag gaggtccagc      360

tgtctggaag actcgcctgc gctgtgcact caacaagagt tctgaattta aggaggttcc      420

tgagaggggc cgcatggatg ttgctgagcc ctacaaggtg tatcagttgc tgccaccagg      480

aatcgtctct ggccagccag ggactcagaa agtaccatca aagcgacagc acagttctgt      540

gtcctctgag aggaaggagg aagaggatgc catgcagaac tgcacactca gtccctctgt      600

gctccaggac tccctcaata atgaggagga gggggccagt gggggagcag tccattcaga      660

cattgggagc agcagcagca gcagcagccc tgagccacag gaagttacag acacaactga      720

ggcccccttt caaggggatc agaggtccct ggagtttctg cttcctccag agccagacta      780

ctcactgctg ctcaccttca tctacaacgg gcgcgtggtg ggcgaggccc aggtgcaaag      840

cctggattgc cgccttgtgg ctgagccctc aggctctgag agcagcatgg agcaggtgct      900

gttccccaag cctggcccac tggagcccac gcagcgcctg ctgagccagc ttgagagggg      960

catcctagtg gccagcaacc cccgaggcct cttcgtgcag cgcctttgcc ccatccccat     1020

ctcctggaat gcaccccagg ctccacctgg gccaggcccg catctgctgc ccagcaacga     1080

gtgcgtggag ctcttcagaa ccgcctactt ctgcagagac ttggtcaggt actttcaggg     1140

cctgggcccc ccaccgaagt tccaggtaac actgaatttc tgggaagaga gccatggctc     1200

cagccatact ccacagaatc ttatcacagt gaagatggag caggcctttg cccgatactt     1260

gctggagcag actccagagc agcaggcagc cattctgtcc ctggtgtaga gcctggggga     1320

cccatcttcc acctcacctc tttgttcttc ctgtctcctt tgaagtagac tcattcttca     1380

cacgattgac ctgtcctctt tgtgataatt ctcagtagtt gtccgtgata atcgtgtcct     1440

gaaaatcctc gcacacactg gctggtggag aactcaaggc taatttttta tccttttttt     1500

tttttaattt tgagatatac gccctctttc atctgtaagg gactaggaaa ttccaaatgg     1560

tgtgaaccca gggggccttt ccctcttccc tgacctccca actctaaagc caagcacttt     1620

atattttcct cttagatatt cactaaggac ttaaaataaa attttattga aagaggaaaa     1680

aaaaaaaaaa aaaaaaaaa                                                  1699


<210>  865
<211>  3288
<212>  DNA
<213>  homo sapiens

<400>  865
gctccctccc ctcctagctg gcttcggcgg ggacggcggc ggcggcggcg ggcggggagg       60

gcgtgcgccg gccgagaggt gtcggcggcg aggcaaagga agtttcaagt ggaaggtcgt      120

ccgtcggccg gcgcgtcctc ctgctctcct ccgcagcatc atggcggagc cgagcggctc      180

gcccgtgcac gtccagcttc cccagcaggc ggccccggtg acagcggcgg cggcggcggc      240

cccggcggcc gcgacagcag cgccggcccc ggcagctccc gcggccccgg ccccggcccc      300

ggccccggcg gcacaggctg tcggctggcc catctgcagg gacgcgtacg agctgcagga      360

ggttatcggc agtggagcta ctgctgtggt tcaggcagcc ctatgcaaac ccaggcaaga      420

acgtgtagca ataaaacgga tcaacttgga aaaatgccag accagtatgg atgaactatt      480

aaaagaaatt caagccatga gtcagtgcag ccatcccaac gtagtgacct attacacctc      540

ttttgtggtc aaagatgaac tttggctggt catgaaatta ctaagtggag gttcaatgtt      600

ggatatcata aaatacattg tcaaccgagg agaacacaag aatggagttc tggaagaggc      660

aataatagca acaattctta aagaggtttt ggaaggctta gactatctac acagaaacgg      720

tcagattcac agggatttga aagctggtaa tattcttctg ggtgaggatg gttcagtaca      780

aatagcagat tttggggtaa gtgcgttcct agcaacaggg ggtgatgtta cccgaaataa      840

agtaagaaaa acattcgttg gcaccccatg ttggatggct cctgaagtca tggaacaggt      900

gagaggctat gacttcaagg ctgacatgtg gagttttgga ataactgcca ttgaattagc      960

aacaggagca gcgccttatc acaaatatcc tcccatgaaa gtgttaatgt tgactttgca     1020

aaatgatcca cccactttgg aaacaggggt agaggataaa gaaatgatga aaaagtacgg     1080

caagtccttt agaaaattac tttcactgtg tcttcagaaa gatccttcca aaaggcccac     1140

agcagcagaa cttttaaaat gcaaattctt ccagaaagcc aagaacagag agtacctgat     1200

tgagaagctg cttacaagaa caccagacat agcccaaaga gccaaaaagg taagaagagt     1260

tcctgggtca agtggtcacc ttcataaaac cgaagacggg gactgggagt ggagtgacga     1320

cgagatggat gagaagagcg aagaagggaa agcagctttt tctcaggaaa agtcacgaag     1380

agtaaaagaa gaaaatccag agattgcagt gagtgccagc accatccccg aacaaataca     1440

gtccctctct gtgcacgact ctcagggccc acccaatgct aatgaagact acagagaagc     1500

ttcttcttgt gccgtgaacc tcgttttgag attaagaaac tccagaaagg aacttaatga     1560

catacgattt gagtttactc caggaagaga tacagcagat ggtgtatctc aggagctctt     1620

ctctgctggc ttggtggatg gtcacgatgt agttatagtg gctgctaatt tacagaagat     1680

tgtagatgat cccaaagctt taaaaacatt gacatttaag ttggcttctg gctgtgatgg     1740

gtcggagatt cctgatgaag tgaagctgat tgggtttgct cagttgagtg tcagctgatg     1800

tatgtccctt gatgtcaccc tgatctgtca tgccccaccg ccacccctac tcccttcaac     1860

cctccctctt tctgcccatt tcctcccacc ccctcactcc catttcctag caaaatcaga     1920

agattgtgaa gaggccggct tcaacaaaat gggataaaaa aataattttt taaaacttac     1980

aacactccga gttctgcttt attctctagc aatccacagt acaagaacaa gcaaatgcca     2040

cagctgcacg actgttgctc atttttccaa aagctattta atattcttag caatcaattt     2100

ggatatccct taagtgaaaa gaatctgaaa tacactcagg tggtcttatt tattggcaac     2160

aaaaggaatt ttctatccag aagcctattt ctcctttcat tgttgttatt tctgttataa     2220

tactttaatt gtacatctga caatactgcc tcttttatgt tgtatttaga aattaatata     2280

cttataaaat taagatttat tagccaaact tgaattctag ttttaaaact gactgtgaat     2340

tttatttttc atatatttat gcattacaca ccttagctat aagaaaaaaa gggttttgat     2400

tatatgcttc ttgcagttaa tctcgttatt taaacaaaaa gttttgggtc tgtctttgga     2460

gtatttgtaa cttctaaatt ttgaaatgac tgaattagga atttggatgc ttattctttt     2520

agtctgtttg cctaaaaacc aatttacaat ctgactgtct cttgggagag ggaggtgcct     2580

tgcaaacttt cacattaaga atgtgcctga ggctgcttta ctctggaata gtctcagatc     2640

taaaatttcc tctatataag gtggcatatg ttaagttttg cttcattgga ccgtttagaa     2700

tgctatgtaa aatgttgcca ttctgttaga ttgctaacta tatacccatc tctgatttgg     2760

ctctccttaa gtgataggat ttgttattct aaaggtgata aacttgaaaa tatcagaatc     2820

tgagttttac ttgaaatttt gcagaatacc caggtggagt gaaaattgga agggttttgt     2880

gcaatgacta aaaggtaaaa cgctgttaag gttcaagaat caatactttc aacccaagta     2940

gccctctgct tgactgtata ttatggaact agtaaacctt aggattttga aaattggagt     3000

ctaatctttc aaggaggtgg gctcccagga tggtaccatt gctctttcct agctaaccct     3060

agatatggca gctctttaat gtacttcaaa aagcaaatat atattactaa ggaaaaaaag     3120

ttatttataa ttgccttgtc ataattgtta aggtgttcta gagccatttg catacaattt     3180

aatgtaattt cattccattc tattgtttac acaacgatta ctcgaagatg actgcaaagg     3240

taaaaggaaa ataaaagtgt attgcacaat gagaaaaaaa aaaaaaaa                  3288


<210>  866
<211>  2748
<212>  DNA
<213>  homo sapiens

<400>  866
attttcgcgt ctcctgacga aggggcccga ccgcgccgcg tttcgggagc ggacgtccga       60

gccacggccg aggcccgatt agtccgtccg gcaccgctcg ggcactttcg gaagggaaga      120

ggtggagaac cgacgttcgg gagcattcgg cctcggggac attcggctcg tctcggctcg      180

gcctcgggct gactcggctt ccgccggcgg cgggaacggg cgaaacccgc ggcactaagc      240

tctctctgag aggcagaatt gcgccggccg ccggcgagaa tctgcctaga gccgtccagc      300

cctgtcggcc ggggacgaca gccgcctcag cctgtcagga cagtgaggag agcaggggcc      360

gagtctctcg gaagccctcg tgaggactcg gacctattcg gactgattcg gcttcccact      420

tcggggaact tcgaccctcc tcggttcagg actcggtctc ggctcggcgg cttcgtgcag      480

gttcggctcc tactcgggca gcctctgttc gcctcggctc cgctccgcgg gcggactcgg      540

ctcggctctg ctcggcggct ggctgccttt tcggtcccta ttcgggcggc ggcttcgggc      600

ggcctcggcc cagctcgggc gtcctcttcg ggccccgctt cgggctccgc gaccggcgct      660

tcgggcggtc ccggacggcg ccttcgggaa ggctcggcgg agtccggatg gaggactcgg      720

actcggcggc aaagcagctg ggcctggctg aggcggcggc ggtggcggcc gcggccgctg      780

tggcggcggc ggccgcggcc gcggcaggag gcgaggcgga ggagccggtg ctgagcaggg      840

acgaggactc ggaggaggac gcagactcgg aggcggagcg ggagacgccg cgggtcacgg      900

cagtggcggt gatggcggcg gagcccgggc acatggacat gggcgccgag gccctgcccg      960

gccccgacga ggccgccgct gccgcagcct tcgcagaggt gaccacagtg acagtggcca     1020

acgtgggggc tgctgcagac aatgtcttca ccacgtctgt ggcgaacgcg gcatccatct     1080

caggacatgt tctgtctggt aggacggccc ttcagatcgg ggacagcctg aacaccgaaa     1140

aagcgacact gattgtcgtc cacacagatg ggagcatcgt ggagaccacc gggctgaaag     1200

gcccggcagc tcccctcacc ccaggtcctc agtctcctcc aacccctctg gctcccggcc     1260

aagaaaaagg tggaactaaa tacaactggg acccttctgt gtacgacagt gagctgcccg     1320

tacggtgccg gaacatcagc ggcactctgt acaagaacag gctcggctca ggcggccggg     1380

gacggtgcat caagcagggg gagaactggt acagtcccac cgagtttgag gccatggcag     1440

gaagagccag cagtaaggac tggaaaagaa gcattcgcta cgcgggccga cccttgcagt     1500

gcctcatcca ggatgggatc ttaaaccctc acgctgcctc ttgcacctgt gctgcctgct     1560

gcgacgacat gaccttaagt ggcccagtca ggctttttgt gccttacaaa aggcgcaaga     1620

aggagaatga actgcccaca actcccgtga agaaggactc ccccaagaac atcacattgc     1680

ttccagccac cgcggctacc accttcaccg tgaccccctc gggacagatc acgacctcgg     1740

gggcactgac ctttgaccga gcgtccacgg tagaggccac tgctgtcata tcagagagtc     1800

cggcccaggg cgacgtcttc gcaggggcca cagtccaaga ggccagcgtg cagcccccat     1860

gcagggccag ccaccctgag cctcactacc ccggctatca ggacagctgc cagatcgcac     1920

cgtttccaga agctgcgttg ccaacgtcac atcccaaaat agtgttgaca tccctgcctg     1980

cgctggcggt cccacccccg actcccacca aagcggcacc tcccgcgttg gtcaatgggc     2040

tggagctgtc agagccgcgg agctggctgt acctagaaga gatggtcaac tccttgctca     2100

acacagcgca gcagctgaag acgctgtttg agcaagccaa gcatgccagc acctaccgag     2160

aagctgccac aaaccaggcc aagatccacg ctgacgcaga gcggaaggag cagtcctgcg     2220

ttaactgcgg ccgggaggct atgagcgagt gcaccggctg ccacaaggtc aactactgct     2280

ccaccttctg ccaacgcaag gactggaagg atcaccagca catatgcggc cagtcagcag     2340

ctgtcaccgt ccaggcagac gaagtccacg tggctgaaag cgtgatggag aaggtgaccg     2400

tgtgaggctc catcggccgc cctgggagct ggggcccctc gcactcctgt gaggcttttg     2460

caggtcgaag gcccccctga ggactctggg gggacgttga gaagaggggt gtgggaaggt     2520

aaagaaactt gctggacaag tcattaacac actttaagcg aatggtgccc tgggaagcgc     2580

actccccctg cccgggcccc ctgcccgctc gcggacagat tttttatccc tgggatcatg     2640

agcgtccggt cttgcccaca gggcctgtgc tgcgacgcac atacatacgt gttgtgtctg     2700

tcaataaagt gtaaataagg tctccctgcc ccacaaaaaa aaaaaaaa                  2748


<210>  867
<211>  3784
<212>  DNA
<213>  homo sapiens

<400>  867
cgtttcctcc cctcccctcc actcggccgt ccctccttcc tcctccctcc tccctcctcc       60

tcccgctcct gaagagcgcg ccgcgtgggg gacggcccgg ttacttcctc cagagactga      120

cgagtgcggt gtcgctccag ctcagagctc ccggagccgc ccggccagcg tccggcctcc      180

ctgatcgtct ctggccggcg ccctcgccct cgcccggcgc gcaccgagca gccgcgggcg      240

ccgagcagcc accgtcccga ccaagcgccg gccctgcccg cagcggcagg atgaatgatt      300

tcggaatcaa gaatatggac caggtagccc ctgtggctaa cagttacaga gggacactca      360

agcgccagcc agcctttgac acctttgatg ggtccctgtt tgctgttttt ccttctctaa      420

atgaagagca aacactgcaa gaagtgccaa caggcttgga ttccatttct catgactccg      480

ccaactgtga attgcctttg ttaaccccgt gcagcaaggc tgtgatgagt caagccttaa      540

aagctacctt cagtggcttc aaaaaggaac agcggcgcct gggcattcca aagaacccct      600

ggctgtggag tgagcaacag gtatgccagt ggcttctctg ggccaccaat gagttcagtc      660

tggtgaacgt gaatctgcag aggttcggca tgaatggcca gatgctgtgt aaccttggca      720

aggaacgctt tctggagctg gcacctgact ttgtgggtga cattctctgg gaacatctgg      780

agcaaatgat caaagaaaac caagaaaaga cagaagatca atatgaagaa aattcacacc      840

tcacctccgt tcctcattgg attaacagca atacattagg ttttggcaca gagcaggcgc      900

cctatggaat gcagacacag aattacccca aaggcggcct cctggacagc atgtgtccgg      960

cctccacacc cagcgtactc agctctgagc aggagtttca gatgttcccc aagtctcggc     1020

tcagctccgt cagcgtcacc tactgctctg tcagtcagga cttcccaggc agcaacttga     1080

atttgctcac caacaattct gggactccca aagaccacga ctcccctgag aacggtgcgg     1140

acagcttcga gagctcagac tccctcctcc agtcctggaa cagccagtcg tccttgctgg     1200

atgtgcaacg ggttccttcc ttcgagagct tcgaagatga ctgcagccag tctctctgcc     1260

tcaataagcc aaccatgtct ttcaaggatt acatccaaga gaggagtgac ccagtggagc     1320

aaggcaaacc agttatacct gcagctgtgc tggccggctt cacaggaagt ggacctattc     1380

agctgtggca gtttctcctg gagctgctat cagacaaatc ctgccagtca ttcatcagct     1440

ggactggaga cggatgggag tttaagctcg ccgaccccga tgaggtggcc cgccggtggg     1500

gaaagaggaa aaataagccc aagatgaact acgagaagct gagccggggc ttacgctact     1560

attacgacaa gaacatcatc cacaagacgt cggggaagcg ctacgtgtac cgcttcgtgt     1620

gcgacctcca gaacttgctg gggttcacgc ccgaggaact gcacgccatc ctgggcgtcc     1680

agcccgacac ggaggactga ggtcgccggg accaccctga gccggcccca ggctcgtgga     1740

ctgagtggga agcccatcct gaccagctgc tccgaggacc caggaaaggc aggattgaaa     1800

atgtccagga aagtggccaa gaagcagtgg ccttattgca tcccaaacca cgcctcttga     1860

ccaggctgcc tcccttgtgg cagcaacggc acagctaatt ctactcacag tgcttttaag     1920

tgaaaatggt cgagaaagag gcaccaggaa gccgtcctgg cgcctggcag tccgtgggac     1980

gggatggttc tggctgtttg agattctcaa aggagcgagc atgtcgtgga cacacacaga     2040

ctatttttag attttctttt gccttttgca accaggaaca gcaaatgcaa aaactctttg     2100

agagggtagg agggtgggaa ggaaacaacc atgtcatttc agaagttagt ttgtatatat     2160

tattataatc ttataattgt tctcagaatc ccttaacagt tgtatttaac agaaattgta     2220

tattgtaatt taaaataatt atataactgt atttgaaata agaattcaga catctgaggt     2280

tttatttcat ttttcaatag cacatatgga attttgcaaa gatttaatct gccaagggcc     2340

gactaagaga agttgtaaag tatgtattat ttacatttaa tagacttaca gggataaggc     2400

ctgtgggggg taatccctgc tttttgtgtt tttttgtttg tttgtttgtt tgtttttggg     2460

gggttttctt gccttggttg tctggcaagg actttgtaca tttgggagtt tttatgagaa     2520

acttaaatgt tattatctgg gcttatatct ggcctctgct ttctccttta attgtaaagt     2580

aaaagctata aagcagtatt tttcttgaca aatggcatat gttttccact tctttgcatg     2640

cgtttaagtc agtttataca caaaatggat tttatttttt agtttaactg tgtttctccg     2700

acagctcacc tctctctgac cacccagcca tttccttcct gtgctccacg ttcttctgtg     2760

tgattaaaat aagaatatta tttttggaaa tatgcaactc cttttcagag atcaggaggg     2820

atttatgtag cagctatttt tactgcaaaa gtaattcact ggaaaaaaaa tgtaatttgt     2880

aagaaagctt tatttttatc tcagctctat gtaaagttaa agttactgta cagagctgaa     2940

ggacgggggg cggtaggggt cttgatgaaa cctcttgaac gaagcacagt ttgtcccatc     3000

tttgttcact cgtgtgtctc aaccatctta atagcatgct gctccttttt gctcagtgtc     3060

cacagcaaga tgacgtgatt cttattttct tggacacaga ctattctgag gcacagagcg     3120

gggacttaag atgggaaaga gaaagcatcg gagccattca ttcggagaaa acgttttgat     3180

caaaatggag acttttgtag tcgtttcaaa agagcacctg agtcatgtgt attcccggcc     3240

tttataaatg acccggtcaa gttggtttca aagtccgaca ggcttgtctg tttactagct     3300

gcgtggcctt ggacgggtgg ctgacatctg taaagaatcc tcctgtgatg aaactgagga     3360

atcgggtggc cgggcaagct gggaagagca aagccagagc tgcgctgcct caatacccac     3420

aaaagaccat tcccagtata cataagcaca ggatgttttt ctcaagaggg atgtatttat     3480

cacttggaca tctgtttata atataaacag acatgtgact gggaacatct tgctgccaaa     3540

agaatcctag gcagtggctc attgtatgtg aggttgaacc acgtgaaatt gccaatatta     3600

ggctggcttt tatctacaaa gaaggagttt catggggttc agcctaacag ttatggaaac     3660

tacagtcctt ataaaccatt ggcatggtaa taaacagatc ttaagtataa aaattttgta     3720

attgggcctt tactctctca ataataaagt attttgttta tataaaaaaa aaaaaaaaaa     3780

aaaa                                                                  3784


<210>  868
<211>  6824
<212>  DNA
<213>  homo sapiens

<400>  868
aaggaaacca gcccaatagt ggacctaaca ccccaataat gggaactggc gactcgaaac       60

acacggtttc agtatcccca ggcgccttaa caataagcag cgggttacag aggaaatcga      120

gtctctccgt ggcgcttcca ggctgaggac ccagcgccta ccggccgagc accccctagg      180

gcagaggggc gagggagacc cgcgggaagg ggcagcaagc cgcctgattg acagcccgaa      240

atctgatctt gtgaaagaga cgcggagcca atgggaggca gcgatccatc agtttggatt      300

ggaggcccct ggaggagaag tagaggaaaa accaccgaat tgagctctgt cagaggcgct      360

ttcggcttcc aagggggaag tgctgggcta taattaatgt ttttattaaa tttggaggga      420

agtttttgca gcctttcgcc tagcgtggcc ttcagtcccg ttaggtgcaa agcaagtctc      480

gttgatcgcc attgctagtt ttgcacacgt ttgcgaatca gagctgcccg gggtacaccg      540

accgcgcagg gaaacatcga gagtgtaaat aaatacatcg cctcttgttc ggatttttgc      600

tactaccgaa aatatgtaaa ttgtgaactc tgttggctct ctttggatcc aggttgatag      660

aagtccagat cctgaggaaa tctccagcta aatgctcaaa atataaaata ctgagctgag      720

atttgcgaag agcagcagca tggatggatt ttatgaccag caagtgcctt acatggtcac      780

caatagtcag cgtgggagaa attgtaacga gaaaccaaca aatgtcagga aaagaaaatt      840

cattaacaga gatctggctc atgattcaga agaactcttt caagatctaa gtcaattaca      900

ggaaacatgg cttgcagaag ctcaggtacc tgacaatgat gagcagtttg taccagacta      960

tcaggctgaa agtttggctt ttcatggcct gccactgaaa atcaagaaag aaccccacag     1020

tccatgttca gaaatcagct ctgcctgcag tcaagaacag ccctttaaat tcagctatgg     1080

agaaaagtgc ctgtacaatg tcagtgccta tgatcagaag ccacaagtgg gaatgaggcc     1140

ctccaacccc cccacaccat ccagcacgcc agtgtcccca ctgcatcatg catctccaaa     1200

ctcaactcat acaccgaaac ctgaccgggc cttcccagct cacctccctc catcgcagtc     1260

cataccagat agcagctacc ccatggacca cagatttcgc cgccagcttt ctgaaccctg     1320

taactccttt cctcctttgc cgacgatgcc aagggaagga cgtcctatgt accaacgcca     1380

gatgtctgag ccaaacatcc ccttcccacc acaaggcttt aagcaggagt accacgaccc     1440

agtgtatgaa cacaacacca tggttggcag tgcggccagc caaagctttc cccctcctct     1500

gatgattaaa caggaaccca gagattttgc atatgactca gaagtgccta gctgccactc     1560

catttatatg aggcaagaag gcttcctggc tcatcccagc agaacagaag gctgtatgtt     1620

tgaaaagggc cccaggcagt tttatgatga cacctgtgtt gtcccagaaa aattcgatgg     1680

agacatcaaa caagagccag gaatgtatcg ggaaggaccc acataccaac ggcgaggatc     1740

acttcagctc tggcagtttt tggtagctct tctggatgac ccttcaaatt ctcattttat     1800

tgcctggact ggtcgaggca tggaatttaa actgattgag cctgaagagg tggcccgacg     1860

ttggggcatt cagaaaaaca ggccagctat gaactatgat aaacttagcc gttcactccg     1920

ctattactat gagaaaggaa ttatgcaaaa ggtggctgga gagagatatg tctacaagtt     1980

tgtgtgtgat ccagaagccc ttttctccat ggcctttcca gataatcagc gtccactgct     2040

gaagacagac atggaacgtc acatcaacga ggaggacaca gtgcctcttt ctcactttga     2100

tgagagcatg gcctacatgc cggaaggggg ctgctgcaac ccccacccct acaacgaagg     2160

ctacgtgtat taacacaagt gacagtcaag cagggcgttt ttgcgctttt ccttttttct     2220

gcaagataca gagaattgct gaatctttgt tttatttctg ttgtttgtat tttattttta     2280

aataataata cacaaaaagg ggcttttcct gttgcattat tctatggtct gccatggact     2340

gtgcacttta tttgagggtg ggtgggagta atctaaacat ttattctgtg taacaggaag     2400

ctaatgggtg aatgggcaga gggatttggg gattactttt tacttaggct tgggatgggg     2460

tcctacaagt tttgagtatg atgaaactat atcatgtctg tttgatttca taacaacata     2520

agataatgtt tattttatcg gggtatctat ggtacagtta atttcacgtt gtgtaaatat     2580

ccacttggag actatttgcc ttgggcattt tcccctgtca tttatgagtc tctgcaggtg     2640

tacaaaaaaa ccccaatcta ctgtaaatgg cagtttaatt gttagaaatg actgtttttg     2700

caccacttgt aaaaaggtat ttagcgattg catttgctgt ttgttgtttt attttgcttt     2760

atatatgact tgcagaggat aaccataaaa tgggtaattc tctctgaagt tgaataatca     2820

ccatgactgt aaatgagggg cacaattttg gactctggcg ccaaactgag tcataggcca     2880

gtagcattac gtgtatctgg tgccaccttg ctgtttagat acaaatcata ccgtctttta     2940

aatattttga agcccatttc agttaaataa tgacatgtca tggtcctttg gaatcttcat     3000

ttaaatgtta aatctggaat caaaatgaag caaaaaatat ctgtctcctt ttcactttct     3060

tcagtacata aatacattat ttaatcaata agaattaact gtactaaatc atgtattatg     3120

ctgttctagt tacagcaaac actctttaag aaaaatatcc aatacactaa ataggtacta     3180

tagtaatttt tagacatggt acccattgat atgcatttaa accttttact gctgtgttat     3240

gttgataaca tatataaata ttagataatg ctaatgcttc tgctgctgtc ttttctgtaa     3300

tattctcttt catgctgaat ttactatgac catttataag cagtgcagtt aactacagat     3360

agcatttcag gacaaaatag atgactcaaa ccatttattg cttaaaaaat agcttacgcc     3420

atgctatgct ataagcagct tttatgcaca ttgacaaatg aagagtaagc ttcagcttgc     3480

taaaggaaac tgtggaacct tttgtaactt ttggtgatat ggaaaattat ttacaaaccg     3540

tcaaagaata tgaggaagtt gctgtatgac atagtgctgg cactgatatt atccatcatc     3600

tctttttgga cacttctgta aatgtgattg gattgtttga aagaagattt aaagtttcaa     3660

agttttttgt tctgtttttg ctttgcattt ggagaaaata ttgaaagcag ggtatgttgt     3720

ttcattcacc ttgaaaaaac catgagtaaa tggggatata gaatctctga atagctcgct     3780

aaaagattca agcaagggac atgaattttg ttccatctat caataatatc cagaagaaca     3840

acttttttaa agagtctata gcaaaaagca aaaaaaaaaa aaaattctaa acacaaagtc     3900

aaaataaacc tattgtaaaa gcatttcgtg atgagcatga aaaagattgt ttaaagatga     3960

tccccccagc tacccatttt ccaaaactac acagatcaca gctcatttct ctaagtggag     4020

cagttatcaa gaaacccaaa caccaaaatt gctactcttc acatttaatc ctacaaaaag     4080

tactccaatt tcaaaatatg tatgtaacct gcgatttcaa tgattgttgt tcatatacat     4140

catgtattat tttggcccat tttgggccta aaaaagaaaa ctatgcctta aaaatcagaa     4200

ccttttctcc ccactatgct tatgtggcca tctacagcac ttagaataaa aacagatgtt     4260

aaaatattca gtgaaagttt tattggaaaa aggaattgag atatataatt gagatttggt     4320

gaaattgaag gagaaaattt aagtgagtct ttaaaatata ttctgaatga aaactgtatt     4380

gaggattcat ttttgttcct tttttttctt tttctctttt ctcctttttc ttctttttaa     4440

tagtctagtt ttagtcagtc agtgaggaag aattgggcca tgctaacgtt atcacaagag     4500

aacaatggca gaaatggtat tagttatata atatttaagg acaaactata tgttttgctg     4560

ttttaacgta gtgactcact gaactaaata cataattgac caacattaag tgtatttcca     4620

atacagaagg gttgaaaata ttacattata aactcttttg aaaaatgtat ctaaaatttt     4680

ttaagttctg ttttgattcc actttttggt tgagttttta tgtttttgtt ttcaggtaga     4740

ttaataaatc tggcagctga tttctgcaag attcttgtgt tttgaatttc tcattgaatt     4800

ggctactcaa acatagaaat catttgttaa tgatgtaatg tcttctctca gcttttatct     4860

tcactgctgt ttgctgtctc ttgatgatga catgttaata cccaatagat taattgcaac     4920

aaacacttat actcaaataa ctaagtaaaa ataatttttc ttgttatgtc catgaaaagt     4980

gcttcagaat aaaaatccac aagactgaca gtgcagaaca tttttctcaa atcatgggcg     5040

gatcttggag gtctagtttc ccgtagatgc tgtaaccaat taccacaact tcagtaattt     5100

acacaaattt atcttatagt tctggaggca gaagttcaaa agaagcctta agagactaaa     5160

accaagatgt ccttaggtct ggttccttct ggaggctcca ggggagattc ttccagcttt     5220

cacttctaga gtctgctgac attccttggc tcctggctac atcacttcaa tctctgcttc     5280

catggtcaca tactcttcta ctatagtcaa atttccttcc tgcctcttat aaggatgctt     5340

gtgattacat ttaggggatg ctcagataat ccaggacaat ctctccatct caagatcctt     5400

aacttaatga cgtgtgccaa gtccctttgg ctagataatt attcataggt cccagggatt     5460

aggacatgga tgtaaggggt gagggcaggg ctgttattca gaacaccgca cggaggagga     5520

agactgtgta gcaaagactc taattgattt actcaggaac agtggagttc tgctgaggga     5580

tctaggattt gaaagtacta gagtttgctt ttatttacca ctgagatatt ttccccttat     5640

tctgcataaa taattttgaa aactttctat attaaatttc aactattcca ctaaaatgtc     5700

tggtaatcac atcaagcctt tagattattc aaatccttcc ccagccccca ggaaaacact     5760

aagtcatgaa acagaaaaac agaaggtatg ataataatag taataacagt taaatcagtg     5820

gtctaatcca gattttattt tttaatacat ttcttttggt gttaatatgg gttactatgt     5880

gatcttatca tttgctagtg attattactt attaggtaag aacaatgtgt aaaatatgtc     5940

tattactcaa aagaacaatt gcaaaatgag tcaacttatc tttatataac caggaaagaa     6000

atatattgcc agaagctaca gaattttgcc agatgatagg gatttctaaa atgagccact     6060

ttgtctatca tgcagccttt tcagagcttg taatgagaaa acattacaga ggagaaggtc     6120

atttggatgt ttgttacttg gaatcctaga aaacaaaaac taaaatttaa aaataagaag     6180

tgagtaagct attttccatt tgcgatttgg tatggagaag agaggaaata gaattattaa     6240

aaaaatacaa attgggtaaa agtgatggtg gaaaaaatat aaagaaggca aatgtacata     6300

ttaagcaatt ctactaagaa ttggaaaaat caagtttcaa aaagatggta atagttgggc     6360

atgatactag aaaatttcac ccagtttatt cagagctcaa ctagtacttt taggacttct     6420

ttttttatat acatgagact cactttgaca tacttaaaaa aaaaacagtt tatggaaagt     6480

acagtttaag aggagaattt gattagacta agtggatatc tttatagaaa tattaatgat     6540

ttcagaattt tcagttacaa gtgtatatac cgtggctatt gtttatggat tcatatgtaa     6600

ggtagggtct tttttgcata tagactccag tattagttac tttcattcta aaattatatt     6660

tatgcttcta tggggaagaa aatttttaat tcacttggtt gtattaaaat tatacttacg     6720

gtttgagaaa acatgctatg aaaatcatga ttatagcaaa ttaaatatgc tcaaaattta     6780

aatctaaaat aaaagcccag aaactgaaaa aaaaaaaaaa aaaa                      6824


<210>  869
<211>  6558
<212>  DNA
<213>  homo sapiens

<400>  869
aaggaaacca gcccaatagt ggacctaaca ccccaataat gggaactggc gactcgaaac       60

acacggtttc agtatcccca ggcgccttaa caataagcag cgggttacag aggaaatcga      120

gtctctccgt ggcgcttcca ggctgaggac ccagcgccta ccggccgagc accccctagg      180

gcagaggggc gagggagacc cgcgggaagg ggcagcaagc cgcctgattg acagcccgaa      240

atctgatctt gtgaaagaga cgcggagcca atgggaggca gcgatccatc agtttggatt      300

ggaggcccct ggaggagaag tagaggaaaa accaccgaat tgagctctgt cagaggcgct      360

ttcggcttcc aagggggaag tgctgggcta taattaatgt ttttattaaa tttggaggga      420

agtttttgca gcctttcgcc tagcgtggcc ttcaggttga tagaagtcca gatcctgagg      480

aaatctccag ctaaatgctc aaaatataaa atactgagct gagatttgcg aagagcagca      540

gcatggatgg attttatgac cagcaagtgc cttacatggt caccaatagt cagcgtggga      600

gaaattgtaa cgagaaacca acaaatgtca ggaaaagaaa attcattaac agagatctgg      660

ctcatgattc agaagaactc tttcaagatc taagtcaatt acaggaaaca tggcttgcag      720

aagctcaggt acctgacaat gatgagcagt ttgtaccaga ctatcaggct gaaagtttgg      780

cttttcatgg cctgccactg aaaatcaaga aagaacccca cagtccatgt tcagaaatca      840

gctctgcctg cagtcaagaa cagcccttta aattcagcta tggagaaaag tgcctgtaca      900

atgtcagtgc ctatgatcag aagccacaag tgggaatgag gccctccaac ccccccacac      960

catccagcac gccagtgtcc ccactgcatc atgcatctcc aaactcaact catacaccga     1020

aacctgaccg ggccttccca gctcacctcc ctccatcgca gtccatacca gatagcagct     1080

accccatgga ccacagattt cgccgccagc tttctgaacc ctgtaactcc tttcctcctt     1140

tgccgacgat gccaagggaa ggacgtccta tgtaccaacg ccagatgtct gagccaaaca     1200

tccccttccc accacaaggc tttaagcagg agtaccacga cccagtgtat gaacacaaca     1260

ccatggttgg cagtgcggcc agccaaagct ttccccctcc tctgatgatt aaacaggaac     1320

ccagagattt tgcatatgac tcaggctgta tgtttgaaaa gggccccagg cagttttatg     1380

atgacacctg tgttgtccca gaaaaattcg atggagacat caaacaagag ccaggaatgt     1440

atcgggaagg acccacatac caacggcgag gatcacttca gctctggcag tttttggtag     1500

ctcttctgga tgacccttca aattctcatt ttattgcctg gactggtcga ggcatggaat     1560

ttaaactgat tgagcctgaa gaggtggccc gacgttgggg cattcagaaa aacaggccag     1620

ctatgaacta tgataaactt agccgttcac tccgctatta ctatgagaaa ggaattatgc     1680

aaaaggtggc tggagagaga tatgtctaca agtttgtgtg tgatccagaa gcccttttct     1740

ccatggcctt tccagataat cagcgtccac tgctgaagac agacatggaa cgtcacatca     1800

acgaggagga cacagtgcct ctttctcact ttgatgagag catggcctac atgccggaag     1860

ggggctgctg caacccccac ccctacaacg aaggctacgt gtattaacac aagtgacagt     1920

caagcagggc gtttttgcgc ttttcctttt ttctgcaaga tacagagaat tgctgaatct     1980

ttgttttatt tctgttgttt gtattttatt tttaaataat aatacacaaa aaggggcttt     2040

tcctgttgca ttattctatg gtctgccatg gactgtgcac tttatttgag ggtgggtggg     2100

agtaatctaa acatttattc tgtgtaacag gaagctaatg ggtgaatggg cagagggatt     2160

tggggattac tttttactta ggcttgggat ggggtcctac aagttttgag tatgatgaaa     2220

ctatatcatg tctgtttgat ttcataacaa cataagataa tgtttatttt atcggggtat     2280

ctatggtaca gttaatttca cgttgtgtaa atatccactt ggagactatt tgccttgggc     2340

attttcccct gtcatttatg agtctctgca ggtgtacaaa aaaaccccaa tctactgtaa     2400

atggcagttt aattgttaga aatgactgtt tttgcaccac ttgtaaaaag gtatttagcg     2460

attgcatttg ctgtttgttg ttttattttg ctttatatat gacttgcaga ggataaccat     2520

aaaatgggta attctctctg aagttgaata atcaccatga ctgtaaatga ggggcacaat     2580

tttggactct ggcgccaaac tgagtcatag gccagtagca ttacgtgtat ctggtgccac     2640

cttgctgttt agatacaaat cataccgtct tttaaatatt ttgaagccca tttcagttaa     2700

ataatgacat gtcatggtcc tttggaatct tcatttaaat gttaaatctg gaatcaaaat     2760

gaagcaaaaa atatctgtct ccttttcact ttcttcagta cataaataca ttatttaatc     2820

aataagaatt aactgtacta aatcatgtat tatgctgttc tagttacagc aaacactctt     2880

taagaaaaat atccaataca ctaaataggt actatagtaa tttttagaca tggtacccat     2940

tgatatgcat ttaaaccttt tactgctgtg ttatgttgat aacatatata aatattagat     3000

aatgctaatg cttctgctgc tgtcttttct gtaatattct ctttcatgct gaatttacta     3060

tgaccattta taagcagtgc agttaactac agatagcatt tcaggacaaa atagatgact     3120

caaaccattt attgcttaaa aaatagctta cgccatgcta tgctataagc agcttttatg     3180

cacattgaca aatgaagagt aagcttcagc ttgctaaagg aaactgtgga accttttgta     3240

acttttggtg atatggaaaa ttatttacaa accgtcaaag aatatgagga agttgctgta     3300

tgacatagtg ctggcactga tattatccat catctctttt tggacacttc tgtaaatgtg     3360

attggattgt ttgaaagaag atttaaagtt tcaaagtttt ttgttctgtt tttgctttgc     3420

atttggagaa aatattgaaa gcagggtatg ttgtttcatt caccttgaaa aaaccatgag     3480

taaatgggga tatagaatct ctgaatagct cgctaaaaga ttcaagcaag ggacatgaat     3540

tttgttccat ctatcaataa tatccagaag aacaactttt ttaaagagtc tatagcaaaa     3600

agcaaaaaaa aaaaaaaatt ctaaacacaa agtcaaaata aacctattgt aaaagcattt     3660

cgtgatgagc atgaaaaaga ttgtttaaag atgatccccc cagctaccca ttttccaaaa     3720

ctacacagat cacagctcat ttctctaagt ggagcagtta tcaagaaacc caaacaccaa     3780

aattgctact cttcacattt aatcctacaa aaagtactcc aatttcaaaa tatgtatgta     3840

acctgcgatt tcaatgattg ttgttcatat acatcatgta ttattttggc ccattttggg     3900

cctaaaaaag aaaactatgc cttaaaaatc agaacctttt ctccccacta tgcttatgtg     3960

gccatctaca gcacttagaa taaaaacaga tgttaaaata ttcagtgaaa gttttattgg     4020

aaaaaggaat tgagatatat aattgagatt tggtgaaatt gaaggagaaa atttaagtga     4080

gtctttaaaa tatattctga atgaaaactg tattgaggat tcatttttgt tccttttttt     4140

tctttttctc ttttctcctt tttcttcttt ttaatagtct agttttagtc agtcagtgag     4200

gaagaattgg gccatgctaa cgttatcaca agagaacaat ggcagaaatg gtattagtta     4260

tataatattt aaggacaaac tatatgtttt gctgttttaa cgtagtgact cactgaacta     4320

aatacataat tgaccaacat taagtgtatt tccaatacag aagggttgaa aatattacat     4380

tataaactct tttgaaaaat gtatctaaaa ttttttaagt tctgttttga ttccactttt     4440

tggttgagtt tttatgtttt tgttttcagg tagattaata aatctggcag ctgatttctg     4500

caagattctt gtgttttgaa tttctcattg aattggctac tcaaacatag aaatcatttg     4560

ttaatgatgt aatgtcttct ctcagctttt atcttcactg ctgtttgctg tctcttgatg     4620

atgacatgtt aatacccaat agattaattg caacaaacac ttatactcaa ataactaagt     4680

aaaaataatt tttcttgtta tgtccatgaa aagtgcttca gaataaaaat ccacaagact     4740

gacagtgcag aacatttttc tcaaatcatg ggcggatctt ggaggtctag tttcccgtag     4800

atgctgtaac caattaccac aacttcagta atttacacaa atttatctta tagttctgga     4860

ggcagaagtt caaaagaagc cttaagagac taaaaccaag atgtccttag gtctggttcc     4920

ttctggaggc tccaggggag attcttccag ctttcacttc tagagtctgc tgacattcct     4980

tggctcctgg ctacatcact tcaatctctg cttccatggt cacatactct tctactatag     5040

tcaaatttcc ttcctgcctc ttataaggat gcttgtgatt acatttaggg gatgctcaga     5100

taatccagga caatctctcc atctcaagat ccttaactta atgacgtgtg ccaagtccct     5160

ttggctagat aattattcat aggtcccagg gattaggaca tggatgtaag gggtgagggc     5220

agggctgtta ttcagaacac cgcacggagg aggaagactg tgtagcaaag actctaattg     5280

atttactcag gaacagtgga gttctgctga gggatctagg atttgaaagt actagagttt     5340

gcttttattt accactgaga tattttcccc ttattctgca taaataattt tgaaaacttt     5400

ctatattaaa tttcaactat tccactaaaa tgtctggtaa tcacatcaag cctttagatt     5460

attcaaatcc ttccccagcc cccaggaaaa cactaagtca tgaaacagaa aaacagaagg     5520

tatgataata atagtaataa cagttaaatc agtggtctaa tccagatttt attttttaat     5580

acatttcttt tggtgttaat atgggttact atgtgatctt atcatttgct agtgattatt     5640

acttattagg taagaacaat gtgtaaaata tgtctattac tcaaaagaac aattgcaaaa     5700

tgagtcaact tatctttata taaccaggaa agaaatatat tgccagaagc tacagaattt     5760

tgccagatga tagggatttc taaaatgagc cactttgtct atcatgcagc cttttcagag     5820

cttgtaatga gaaaacatta cagaggagaa ggtcatttgg atgtttgtta cttggaatcc     5880

tagaaaacaa aaactaaaat ttaaaaataa gaagtgagta agctattttc catttgcgat     5940

ttggtatgga gaagagagga aatagaatta ttaaaaaaat acaaattggg taaaagtgat     6000

ggtggaaaaa atataaagaa ggcaaatgta catattaagc aattctacta agaattggaa     6060

aaatcaagtt tcaaaaagat ggtaatagtt gggcatgata ctagaaaatt tcacccagtt     6120

tattcagagc tcaactagta cttttaggac ttcttttttt atatacatga gactcacttt     6180

gacatactta aaaaaaaaac agtttatgga aagtacagtt taagaggaga atttgattag     6240

actaagtgga tatctttata gaaatattaa tgatttcaga attttcagtt acaagtgtat     6300

ataccgtggc tattgtttat ggattcatat gtaaggtagg gtcttttttg catatagact     6360

ccagtattag ttactttcat tctaaaatta tatttatgct tctatgggga agaaaatttt     6420

taattcactt ggttgtatta aaattatact tacggtttga gaaaacatgc tatgaaaatc     6480

atgattatag caaattaaat atgctcaaaa tttaaatcta aaataaaagc ccagaaactg     6540

aaaaaaaaaa aaaaaaaa                                                   6558


<210>  870
<211>  6366
<212>  DNA
<213>  homo sapiens

<400>  870
cgttattggc tgcgggaaga acctcgccgg gacctaaccc gaagctccgc cccctcgcgg       60

ttaccctgga tacccgtcag gctcgggctg cagagaagga ggatcagggc aagtggcttc      120

agagatgcag ccctcactgc ttaacgtcct agttattgtc cttgaaaccc gagccatctc      180

accgctcgcc cccaaccctg ggctctggct gtttaaaagc tggagaggaa gtgaaagcgt      240

caagtacagt tgatagaagt ccagatcctg aggaaatctc cagctaaatg ctcaaaatat      300

aaaatactga gctgagattt gcgaagagca gcagcatgga tggattttat gaccagcaag      360

tgccttacat ggtcaccaat agtcagcgtg ggagaaattg taacgagaaa ccaacaaatg      420

tcaggaaaag aaaattcatt aacagagatc tggctcatga ttcagaagaa ctctttcaag      480

atctaagtca attacaggaa acatggcttg cagaagtggc ttttcatggc ctgccactga      540

aaatcaagaa agaaccccac agtccatgtt cagaaatcag ctctgcctgc agtcaagaac      600

agccctttaa attcagctat ggagaaaagt gcctgtacaa tgtcagtgcc tatgatcaga      660

agccacaagt gggaatgagg ccctccaacc cccccacacc atccagcacg ccagtgtccc      720

cactgcatca tgcatctcca aactcaactc atacaccgaa acctgaccgg gccttcccag      780

ctcacctccc tccatcgcag tccataccag atagcagcta ccccatggac cacagatttc      840

gccgccagct ttctgaaccc tgtaactcct ttcctccttt gccgacgatg ccaagggaag      900

gacgtcctat gtaccaacgc cagatgtctg agccaaacat ccccttccca ccacaaggct      960

ttaagcagga gtaccacgac ccagtgtatg aacacaacac catggttggc agtgcggcca     1020

gccaaagctt tccccctcct ctgatgatta aacaggaacc cagagatttt gcatatgact     1080

cagaagtgcc tagctgccac tccatttata tgaggcaaga aggcttcctg gctcatccca     1140

gcagaacaga aggctgtatg tttgaaaagg gccccaggca gttttatgat gacacctgtg     1200

ttgtcccaga aaaattcgat ggagacatca aacaagagcc aggaatgtat cgggaaggac     1260

ccacatacca acggcgagga tcacttcagc tctggcagtt tttggtagct cttctggatg     1320

acccttcaaa ttctcatttt attgcctgga ctggtcgagg catggaattt aaactgattg     1380

agcctgaaga ggtggcccga cgttggggca ttcagaaaaa caggccagct atgaactatg     1440

ataaacttag ccgttcactc cgctattact atgagaaagg aattatgcaa aaggtggctg     1500

gagagagata tgtctacaag tttgtgtgtg atccagaagc ccttttctcc atggcctttc     1560

cagataatca gcgtccactg ctgaagacag acatggaacg tcacatcaac gaggaggaca     1620

cagtgcctct ttctcacttt gatgagagca tggcctacat gccggaaggg ggctgctgca     1680

acccccaccc ctacaacgaa ggctacgtgt attaacacaa gtgacagtca agcagggcgt     1740

ttttgcgctt ttcctttttt ctgcaagata cagagaattg ctgaatcttt gttttatttc     1800

tgttgtttgt attttatttt taaataataa tacacaaaaa ggggcttttc ctgttgcatt     1860

attctatggt ctgccatgga ctgtgcactt tatttgaggg tgggtgggag taatctaaac     1920

atttattctg tgtaacagga agctaatggg tgaatgggca gagggatttg gggattactt     1980

tttacttagg cttgggatgg ggtcctacaa gttttgagta tgatgaaact atatcatgtc     2040

tgtttgattt cataacaaca taagataatg tttattttat cggggtatct atggtacagt     2100

taatttcacg ttgtgtaaat atccacttgg agactatttg ccttgggcat tttcccctgt     2160

catttatgag tctctgcagg tgtacaaaaa aaccccaatc tactgtaaat ggcagtttaa     2220

ttgttagaaa tgactgtttt tgcaccactt gtaaaaaggt atttagcgat tgcatttgct     2280

gtttgttgtt ttattttgct ttatatatga cttgcagagg ataaccataa aatgggtaat     2340

tctctctgaa gttgaataat caccatgact gtaaatgagg ggcacaattt tggactctgg     2400

cgccaaactg agtcataggc cagtagcatt acgtgtatct ggtgccacct tgctgtttag     2460

atacaaatca taccgtcttt taaatatttt gaagcccatt tcagttaaat aatgacatgt     2520

catggtcctt tggaatcttc atttaaatgt taaatctgga atcaaaatga agcaaaaaat     2580

atctgtctcc ttttcacttt cttcagtaca taaatacatt atttaatcaa taagaattaa     2640

ctgtactaaa tcatgtatta tgctgttcta gttacagcaa acactcttta agaaaaatat     2700

ccaatacact aaataggtac tatagtaatt tttagacatg gtacccattg atatgcattt     2760

aaacctttta ctgctgtgtt atgttgataa catatataaa tattagataa tgctaatgct     2820

tctgctgctg tcttttctgt aatattctct ttcatgctga atttactatg accatttata     2880

agcagtgcag ttaactacag atagcatttc aggacaaaat agatgactca aaccatttat     2940

tgcttaaaaa atagcttacg ccatgctatg ctataagcag cttttatgca cattgacaaa     3000

tgaagagtaa gcttcagctt gctaaaggaa actgtggaac cttttgtaac ttttggtgat     3060

atggaaaatt atttacaaac cgtcaaagaa tatgaggaag ttgctgtatg acatagtgct     3120

ggcactgata ttatccatca tctctttttg gacacttctg taaatgtgat tggattgttt     3180

gaaagaagat ttaaagtttc aaagtttttt gttctgtttt tgctttgcat ttggagaaaa     3240

tattgaaagc agggtatgtt gtttcattca ccttgaaaaa accatgagta aatggggata     3300

tagaatctct gaatagctcg ctaaaagatt caagcaaggg acatgaattt tgttccatct     3360

atcaataata tccagaagaa caactttttt aaagagtcta tagcaaaaag caaaaaaaaa     3420

aaaaaattct aaacacaaag tcaaaataaa cctattgtaa aagcatttcg tgatgagcat     3480

gaaaaagatt gtttaaagat gatcccccca gctacccatt ttccaaaact acacagatca     3540

cagctcattt ctctaagtgg agcagttatc aagaaaccca aacaccaaaa ttgctactct     3600

tcacatttaa tcctacaaaa agtactccaa tttcaaaata tgtatgtaac ctgcgatttc     3660

aatgattgtt gttcatatac atcatgtatt attttggccc attttgggcc taaaaaagaa     3720

aactatgcct taaaaatcag aaccttttct ccccactatg cttatgtggc catctacagc     3780

acttagaata aaaacagatg ttaaaatatt cagtgaaagt tttattggaa aaaggaattg     3840

agatatataa ttgagatttg gtgaaattga aggagaaaat ttaagtgagt ctttaaaata     3900

tattctgaat gaaaactgta ttgaggattc atttttgttc cttttttttc tttttctctt     3960

ttctcctttt tcttcttttt aatagtctag ttttagtcag tcagtgagga agaattgggc     4020

catgctaacg ttatcacaag agaacaatgg cagaaatggt attagttata taatatttaa     4080

ggacaaacta tatgttttgc tgttttaacg tagtgactca ctgaactaaa tacataattg     4140

accaacatta agtgtatttc caatacagaa gggttgaaaa tattacatta taaactcttt     4200

tgaaaaatgt atctaaaatt ttttaagttc tgttttgatt ccactttttg gttgagtttt     4260

tatgtttttg ttttcaggta gattaataaa tctggcagct gatttctgca agattcttgt     4320

gttttgaatt tctcattgaa ttggctactc aaacatagaa atcatttgtt aatgatgtaa     4380

tgtcttctct cagcttttat cttcactgct gtttgctgtc tcttgatgat gacatgttaa     4440

tacccaatag attaattgca acaaacactt atactcaaat aactaagtaa aaataatttt     4500

tcttgttatg tccatgaaaa gtgcttcaga ataaaaatcc acaagactga cagtgcagaa     4560

catttttctc aaatcatggg cggatcttgg aggtctagtt tcccgtagat gctgtaacca     4620

attaccacaa cttcagtaat ttacacaaat ttatcttata gttctggagg cagaagttca     4680

aaagaagcct taagagacta aaaccaagat gtccttaggt ctggttcctt ctggaggctc     4740

caggggagat tcttccagct ttcacttcta gagtctgctg acattccttg gctcctggct     4800

acatcacttc aatctctgct tccatggtca catactcttc tactatagtc aaatttcctt     4860

cctgcctctt ataaggatgc ttgtgattac atttagggga tgctcagata atccaggaca     4920

atctctccat ctcaagatcc ttaacttaat gacgtgtgcc aagtcccttt ggctagataa     4980

ttattcatag gtcccaggga ttaggacatg gatgtaaggg gtgagggcag ggctgttatt     5040

cagaacaccg cacggaggag gaagactgtg tagcaaagac tctaattgat ttactcagga     5100

acagtggagt tctgctgagg gatctaggat ttgaaagtac tagagtttgc ttttatttac     5160

cactgagata ttttcccctt attctgcata aataattttg aaaactttct atattaaatt     5220

tcaactattc cactaaaatg tctggtaatc acatcaagcc tttagattat tcaaatcctt     5280

ccccagcccc caggaaaaca ctaagtcatg aaacagaaaa acagaaggta tgataataat     5340

agtaataaca gttaaatcag tggtctaatc cagattttat tttttaatac atttcttttg     5400

gtgttaatat gggttactat gtgatcttat catttgctag tgattattac ttattaggta     5460

agaacaatgt gtaaaatatg tctattactc aaaagaacaa ttgcaaaatg agtcaactta     5520

tctttatata accaggaaag aaatatattg ccagaagcta cagaattttg ccagatgata     5580

gggatttcta aaatgagcca ctttgtctat catgcagcct tttcagagct tgtaatgaga     5640

aaacattaca gaggagaagg tcatttggat gtttgttact tggaatccta gaaaacaaaa     5700

actaaaattt aaaaataaga agtgagtaag ctattttcca tttgcgattt ggtatggaga     5760

agagaggaaa tagaattatt aaaaaaatac aaattgggta aaagtgatgg tggaaaaaat     5820

ataaagaagg caaatgtaca tattaagcaa ttctactaag aattggaaaa atcaagtttc     5880

aaaaagatgg taatagttgg gcatgatact agaaaatttc acccagttta ttcagagctc     5940

aactagtact tttaggactt ctttttttat atacatgaga ctcactttga catacttaaa     6000

aaaaaaacag tttatggaaa gtacagttta agaggagaat ttgattagac taagtggata     6060

tctttataga aatattaatg atttcagaat tttcagttac aagtgtatat accgtggcta     6120

ttgtttatgg attcatatgt aaggtagggt cttttttgca tatagactcc agtattagtt     6180

actttcattc taaaattata tttatgcttc tatggggaag aaaattttta attcacttgg     6240

ttgtattaaa attatactta cggtttgaga aaacatgcta tgaaaatcat gattatagca     6300

aattaaatat gctcaaaatt taaatctaaa ataaaagccc agaaactgaa aaaaaaaaaa     6360

aaaaaa                                                                6366


<210>  871
<211>  6237
<212>  DNA
<213>  homo sapiens

<400>  871
ttggttgcac cctcagatag tacccatgag cttcactgtt cagcctcggg gcccaggcgc       60

ttcctggaat ctctccttgg ccggggttaa aatgcagttc ccgctcaaaa tgcttatagg      120

ttgatagaag tccagatcct gaggaaatct ccagctaaat gctcaaaata taaaatactg      180

agctgagatt tgcgaagagc agcagcatgg atggatttta tgaccagcaa gtgccttaca      240

tggtcaccaa tagtcagcgt gggagaaatt gtaacgagaa accaacaaat gtcaggaaaa      300

gaaaattcat taacagagat ctggctcatg attcagaaga actctttcaa gatctaagtc      360

aattacagga aacatggctt gcagaagtgg cttttcatgg cctgccactg aaaatcaaga      420

aagaacccca cagtccatgt tcagaaatca gctctgcctg cagtcaagaa cagcccttta      480

aattcagcta tggagaaaag tgcctgtaca atgtcagtgc ctatgatcag aagccacaag      540

tgggaatgag gccctccaac ccccccacac catccagcac gccagtgtcc ccactgcatc      600

atgcatctcc aaactcaact catacaccga aacctgaccg ggccttccca gctcacctcc      660

ctccatcgca gtccatacca gatagcagct accccatgga ccacagattt cgccgccagc      720

tttctgaacc ctgtaactcc tttcctcctt tgccgacgat gccaagggaa ggacgtccta      780

tgtaccaacg ccagatgtct gagccaaaca tccccttccc accacaaggc tttaagcagg      840

agtaccacga cccagtgtat gaacacaaca ccatggttgg cagtgcggcc agccaaagct      900

ttccccctcc tctgatgatt aaacaggaac ccagagattt tgcatatgac tcagaagtgc      960

ctagctgcca ctccatttat atgaggcaag aaggcttcct ggctcatccc agcagaacag     1020

aaggctgtat gtttgaaaag ggccccaggc agttttatga tgacacctgt gttgtcccag     1080

aaaaattcga tggagacatc aaacaagagc caggaatgta tcgggaagga cccacatacc     1140

aacggcgagg atcacttcag ctctggcagt ttttggtagc tcttctggat gacccttcaa     1200

attctcattt tattgcctgg actggtcgag gcatggaatt taaactgatt gagcctgaag     1260

aggtggcccg acgttggggc attcagaaaa acaggccagc tatgaactat gataaactta     1320

gccgttcact ccgctattac tatgagaaag gaattatgca aaaggtggct ggagagagat     1380

atgtctacaa gtttgtgtgt gatccagaag cccttttctc catggccttt ccagataatc     1440

agcgtccact gctgaagaca gacatggaac gtcacatcaa cgaggaggac acagtgcctc     1500

tttctcactt tgatgagagc atggcctaca tgccggaagg gggctgctgc aacccccacc     1560

cctacaacga aggctacgtg tattaacaca agtgacagtc aagcagggcg tttttgcgct     1620

tttccttttt tctgcaagat acagagaatt gctgaatctt tgttttattt ctgttgtttg     1680

tattttattt ttaaataata atacacaaaa aggggctttt cctgttgcat tattctatgg     1740

tctgccatgg actgtgcact ttatttgagg gtgggtggga gtaatctaaa catttattct     1800

gtgtaacagg aagctaatgg gtgaatgggc agagggattt ggggattact ttttacttag     1860

gcttgggatg gggtcctaca agttttgagt atgatgaaac tatatcatgt ctgtttgatt     1920

tcataacaac ataagataat gtttatttta tcggggtatc tatggtacag ttaatttcac     1980

gttgtgtaaa tatccacttg gagactattt gccttgggca ttttcccctg tcatttatga     2040

gtctctgcag gtgtacaaaa aaaccccaat ctactgtaaa tggcagttta attgttagaa     2100

atgactgttt ttgcaccact tgtaaaaagg tatttagcga ttgcatttgc tgtttgttgt     2160

tttattttgc tttatatatg acttgcagag gataaccata aaatgggtaa ttctctctga     2220

agttgaataa tcaccatgac tgtaaatgag gggcacaatt ttggactctg gcgccaaact     2280

gagtcatagg ccagtagcat tacgtgtatc tggtgccacc ttgctgttta gatacaaatc     2340

ataccgtctt ttaaatattt tgaagcccat ttcagttaaa taatgacatg tcatggtcct     2400

ttggaatctt catttaaatg ttaaatctgg aatcaaaatg aagcaaaaaa tatctgtctc     2460

cttttcactt tcttcagtac ataaatacat tatttaatca ataagaatta actgtactaa     2520

atcatgtatt atgctgttct agttacagca aacactcttt aagaaaaata tccaatacac     2580

taaataggta ctatagtaat ttttagacat ggtacccatt gatatgcatt taaacctttt     2640

actgctgtgt tatgttgata acatatataa atattagata atgctaatgc ttctgctgct     2700

gtcttttctg taatattctc tttcatgctg aatttactat gaccatttat aagcagtgca     2760

gttaactaca gatagcattt caggacaaaa tagatgactc aaaccattta ttgcttaaaa     2820

aatagcttac gccatgctat gctataagca gcttttatgc acattgacaa atgaagagta     2880

agcttcagct tgctaaagga aactgtggaa ccttttgtaa cttttggtga tatggaaaat     2940

tatttacaaa ccgtcaaaga atatgaggaa gttgctgtat gacatagtgc tggcactgat     3000

attatccatc atctcttttt ggacacttct gtaaatgtga ttggattgtt tgaaagaaga     3060

tttaaagttt caaagttttt tgttctgttt ttgctttgca tttggagaaa atattgaaag     3120

cagggtatgt tgtttcattc accttgaaaa aaccatgagt aaatggggat atagaatctc     3180

tgaatagctc gctaaaagat tcaagcaagg gacatgaatt ttgttccatc tatcaataat     3240

atccagaaga acaacttttt taaagagtct atagcaaaaa gcaaaaaaaa aaaaaaattc     3300

taaacacaaa gtcaaaataa acctattgta aaagcatttc gtgatgagca tgaaaaagat     3360

tgtttaaaga tgatcccccc agctacccat tttccaaaac tacacagatc acagctcatt     3420

tctctaagtg gagcagttat caagaaaccc aaacaccaaa attgctactc ttcacattta     3480

atcctacaaa aagtactcca atttcaaaat atgtatgtaa cctgcgattt caatgattgt     3540

tgttcatata catcatgtat tattttggcc cattttgggc ctaaaaaaga aaactatgcc     3600

ttaaaaatca gaaccttttc tccccactat gcttatgtgg ccatctacag cacttagaat     3660

aaaaacagat gttaaaatat tcagtgaaag ttttattgga aaaaggaatt gagatatata     3720

attgagattt ggtgaaattg aaggagaaaa tttaagtgag tctttaaaat atattctgaa     3780

tgaaaactgt attgaggatt catttttgtt cctttttttt ctttttctct tttctccttt     3840

ttcttctttt taatagtcta gttttagtca gtcagtgagg aagaattggg ccatgctaac     3900

gttatcacaa gagaacaatg gcagaaatgg tattagttat ataatattta aggacaaact     3960

atatgttttg ctgttttaac gtagtgactc actgaactaa atacataatt gaccaacatt     4020

aagtgtattt ccaatacaga agggttgaaa atattacatt ataaactctt ttgaaaaatg     4080

tatctaaaat tttttaagtt ctgttttgat tccacttttt ggttgagttt ttatgttttt     4140

gttttcaggt agattaataa atctggcagc tgatttctgc aagattcttg tgttttgaat     4200

ttctcattga attggctact caaacataga aatcatttgt taatgatgta atgtcttctc     4260

tcagctttta tcttcactgc tgtttgctgt ctcttgatga tgacatgtta atacccaata     4320

gattaattgc aacaaacact tatactcaaa taactaagta aaaataattt ttcttgttat     4380

gtccatgaaa agtgcttcag aataaaaatc cacaagactg acagtgcaga acatttttct     4440

caaatcatgg gcggatcttg gaggtctagt ttcccgtaga tgctgtaacc aattaccaca     4500

acttcagtaa tttacacaaa tttatcttat agttctggag gcagaagttc aaaagaagcc     4560

ttaagagact aaaaccaaga tgtccttagg tctggttcct tctggaggct ccaggggaga     4620

ttcttccagc tttcacttct agagtctgct gacattcctt ggctcctggc tacatcactt     4680

caatctctgc ttccatggtc acatactctt ctactatagt caaatttcct tcctgcctct     4740

tataaggatg cttgtgatta catttagggg atgctcagat aatccaggac aatctctcca     4800

tctcaagatc cttaacttaa tgacgtgtgc caagtccctt tggctagata attattcata     4860

ggtcccaggg attaggacat ggatgtaagg ggtgagggca gggctgttat tcagaacacc     4920

gcacggagga ggaagactgt gtagcaaaga ctctaattga tttactcagg aacagtggag     4980

ttctgctgag ggatctagga tttgaaagta ctagagtttg cttttattta ccactgagat     5040

attttcccct tattctgcat aaataatttt gaaaactttc tatattaaat ttcaactatt     5100

ccactaaaat gtctggtaat cacatcaagc ctttagatta ttcaaatcct tccccagccc     5160

ccaggaaaac actaagtcat gaaacagaaa aacagaaggt atgataataa tagtaataac     5220

agttaaatca gtggtctaat ccagatttta ttttttaata catttctttt ggtgttaata     5280

tgggttacta tgtgatctta tcatttgcta gtgattatta cttattaggt aagaacaatg     5340

tgtaaaatat gtctattact caaaagaaca attgcaaaat gagtcaactt atctttatat     5400

aaccaggaaa gaaatatatt gccagaagct acagaatttt gccagatgat agggatttct     5460

aaaatgagcc actttgtcta tcatgcagcc ttttcagagc ttgtaatgag aaaacattac     5520

agaggagaag gtcatttgga tgtttgttac ttggaatcct agaaaacaaa aactaaaatt     5580

taaaaataag aagtgagtaa gctattttcc atttgcgatt tggtatggag aagagaggaa     5640

atagaattat taaaaaaata caaattgggt aaaagtgatg gtggaaaaaa tataaagaag     5700

gcaaatgtac atattaagca attctactaa gaattggaaa aatcaagttt caaaaagatg     5760

gtaatagttg ggcatgatac tagaaaattt cacccagttt attcagagct caactagtac     5820

ttttaggact tcttttttta tatacatgag actcactttg acatacttaa aaaaaaaaca     5880

gtttatggaa agtacagttt aagaggagaa tttgattaga ctaagtggat atctttatag     5940

aaatattaat gatttcagaa ttttcagtta caagtgtata taccgtggct attgtttatg     6000

gattcatatg taaggtaggg tcttttttgc atatagactc cagtattagt tactttcatt     6060

ctaaaattat atttatgctt ctatggggaa gaaaattttt aattcacttg gttgtattaa     6120

aattatactt acggtttgag aaaacatgct atgaaaatca tgattatagc aaattaaata     6180

tgctcaaaat ttaaatctaa aataaaagcc cagaaactga aaaaaaaaaa aaaaaaa        6237


<210>  872
<211>  6546
<212>  DNA
<213>  homo sapiens

<400>  872
atttttccac ccagcaggat gggtgatgct gagagctgcc tgctcagaca acagacacgc       60

gaggtcagga agaagccgct tataaattac cgcttccttc gcgccgccgc caacgccgag      120

ccccgaggac cgcaagccca gaggacaagc tgcgccaaga gggagtgcgg agcgttcacc      180

cagcgggtca gagagcgagc gggcaggcag cccccggccg gcggaacccg gcacagccga      240

gcagagcgcg ggcggcgccg cagccacccc agatccagaa ccagaaccac agcccttctg      300

aggagctccc aaacaaagca aggagatggc caccaaggag aagctgcagt gtctgaaaga      360

tttccacaag gacatcctga agccctcacc agggaagagc ccaggcacgc ggcctgagga      420

cgaggctgag ggaaaacctc cgcagaggga gaagtggtct agcaagatcg actttgtgct      480

ctctgtggct ggcggcttcg tgggcttggg caacgtctgg cgcttcccgt acctctgcta      540

caagaatggt ggaggtgcgt ttctcatacc gtattttatt ttcctgtttg ggagcggcct      600

gcctgtgttt ttcttggaga tcatcatagg ccagtacacc tctgaagggg gcatcacctg      660

ctgggaaaag atctgcccct tgttctctgg tatcggctat gcctccgttg taattgtgtc      720

cctcctgaat gtctactaca tcgtcatcct ggcctgggcc acatactacc tgttccagtc      780

cttccagaag gagctgccct gggcacactg caaccacagc tggaacacac ctcactgcat      840

ggaggacacc atgcgcaaga acaagagtgt ctggatcacc atcagctcca ccaacttcac      900

ctcccctgtc atcgagttct gggagcgcaa cgtgctgagc ttgtcccctg gaatcgacca      960

cccaggctct ctgaaatggg acctcgctct ctgccttctt ttagtctggc tagtgtgttt     1020

cttctgcatc tggaagggcg tcaggtccac tgggaaggtc gtctacttca cagccacttt     1080

tccattcgcc atgctcctgg tgctgctggt ccgagggctg acgctgccgg gcgcgggcgc     1140

aggcatcaag ttctatctgt atcctgacat cacccgcctt gaggacccac aggtgtggat     1200

tgacgctggg actcagatat tcttctctta tgccatctgc ctgggggcta tgacctcgct     1260

ggggagctac aacaagtaca agtataactc gtacagggac tgtatgctgc tgggatgcct     1320

gaacagtggt accagttttg tgtctggctt cgcaattttt tccatcctgg gcttcatggc     1380

acaagagcaa ggggtggaca ttgctgatgt ggctgagtca ggtcctggcc tggccttcat     1440

tgcctaccca aaagctgtga caatgatgcc gctgcccaca ttttggtcca ttcttttttt     1500

tattatgctt ctcttgcttg gactggatag ccagtttgtt gaagttgaag gacagatcac     1560

atccttggtt gatctttacc catccttcct aaggaagggt tatcgtcggg aaatcttcat     1620

cgccttcgtg tgtagcatca gctacctgct ggggctgacg atggtgacgg agggtggcat     1680

gtatgtgttt cagctctttg actactatgc agctagcggt gtatgccttt tgtgggttgc     1740

attctttgaa tgttttgtta ttgcctggat atatggaggt gataaccttt atgatggtat     1800

tgaggacatg attggctatc ggcccgggcc ctggatgaag tacagctggg ctgtgatcac     1860

tccagttctc tgtgttggat gtttcatctt ctcgctcgtc aagtacgtac ccctgaccta     1920

caacaaaaca tacgtgtacc ccaactgggc cattgggctg ggctggagcc tggccctttc     1980

ctccatgctc tgcgttccct tggtcatcgt catccgcctc tgccagactg aggggccgtt     2040

ccttgtgaga gtcaagtacc tgctgacccc aagggaaccc aaccgctggg ctgtggagcg     2100

cgagggagcc acaccttaca actctcgcac cgtcatgaac ggcgctctcg tgaaaccgac     2160

ccacatcatt gtggagacca tgatgtgagc tctctcgggt cgacggggcc ggcggctttc     2220

ctgctgttta ctaacattag attctcatag gaccaggttt acagagcttt atatttgcac     2280

taggattttt ttttttttgt aattgtcaca gaaaatgtaa ttgtgggtat gtgtgcgtgc     2340

gtgtgtgtgt gtgtgtgtat cgtgtgtgtg tgttttgttt tgatttgggg gatattttgt     2400

acaaaaagaa aacccacggg aagatgtccg tggagaggca gagctttcat actgaattag     2460

atgtatttta tgggaatttg gtaaattttt ctttgtattt ttttttttac atataagtat     2520

atatacactt agagattgtc atatactttt accacttgaa ttgatcttct tgccagcaat     2580

agatctcatt ttcaaaagca attcttcggt gctgtgtagc tggcagaaag ttctgtccag     2640

taaacgcagg atggaatttt cctgggactc tacacccatc ttaaggtggt ataccttcca     2700

aatcctggtt cagatggaag aaatagcagg agagaggacc cattagctgg cagacccagg     2760

gggaagaaag gagggctgtg aggagatacc tcattaaact tggcttagtg aagaagagag     2820

atgccaaagg aatgaaccaa cccttcacat aaaggagact ggctgaagct gaatgaggag     2880

gccctatagc agaagtctga ttctaagagc agtagaaact tgtaccagaa gcaaaatccc     2940

acttttaatt ttgagatggt gagtggatag tcagtagacc gtcagaacca ctggccagag     3000

agggagctgc tagagatcca agaaggctgg caggagtgag gctcacaact cagcctcgca     3060

agaggtggca gaggcacagg aggccacagt ccttcctggg gcattccagg cagagaagga     3120

gcagaggctc tcccggcagg agctggggtc tcagggctca gatgagtctg ttgcatttga     3180

atggggtcat agcaggttct ggtcattccc caagcaacat ctcagcatct cttaaagttg     3240

cctgcaggaa tgaagcatga catacctgtt gagggactag gggagtggtg gggaggtgag     3300

tggaccaaag gatataggcc ccaggcatgc agatgggccc ggtgtcgggg aggggtgctt     3360

tctttcctca tctccccact ccccactctc agcctgggag actcctgcca agccctcatt     3420

aaagatgcca ccctgggctg ccctggcacc tagcaaggca caccaagaac agcttttgag     3480

tctgtatcct ccactggggg aagtgctccc agttcagaac aagggcagcc cgtggtgctg     3540

acctaggata taacaaagct cttcacttca aaacccctgc aatagctggg tttacagaca     3600

tttaccacct gcggacccaa aagagaaggc ctaggagagt tttctagaag gttgggattg     3660

tcagggtcct ggcccctcag aactggcttg atcaagggcc ttatgtggag cagaggttgt     3720

ctctgaacca ggagagaagg tactatacct ttcaaatccc cagggcagac acacccccac     3780

ccagccccta tttggaccta aactgtgcca tttgaacagt cacttccaag ctcagtctaa     3840

atgaaaccga aacgtgacca cgcacaaagg cagtcactgc ctcgaggggt gcagaccgca     3900

gaattttcac agcaggggct cttggaaccc tggaaacccc cttcttaaat ttgggaggag     3960

gagtatgcct ttggtgtccc cctcccaagg ggcaattctg aaccccatct ttggcaggca     4020

tacatatttc actgtttcca aagctatcta ctctgccaaa caacacccag tcctattcca     4080

aactctcaac gattctatct tgttcctgtt tttctatgta tttatggttg ccgtttgtgt     4140

ctgatttgat tttactgttt tttccctgat tttatggagt agcattgtga cctgttttcc     4200

tttgtcttat ataactttag taaactaacc actgtcaatg attgagggca ggtggcacgt     4260

ggggaagagg ggacttggca cgcagtggct acctgggcat ttgtggtcat ttcagtttcc     4320

atctccccag cgggggctcc ctgggtgaaa ggccacagta ttttgggttg gtaggcaaat     4380

tgcaacattc tggacatggc ctgaggaagg cctcttctta taagattctc agaccaaatt     4440

ctagaccaaa gacacaggca gaccaagtcc ccaggccccg cctggaagga agtcgttcct     4500

caactctccc caaggcacct gtctccaatc agagccctct cgcccagcca gccctggctc     4560

tgtgtgcaga gcatagctct gcgagtacct gtgtaataat gctcaacctt catgtctccg     4620

tataaacgaa actttccatg agagctcatg actctggtcc acctgtctat agagaatggg     4680

caaagtcctt cacctgcttt ctgcttggga tgggtcagaa atgctgatgc ccgcacatag     4740

cccagccagc cagatctgga aaggaagcga gggggttgtt taaatcaatt ttttaagatg     4800

aagaagtggg agacactgcg ttgagatggg ccatgctagg gccacagaga tttcctgacg     4860

gtcagggaga gaagggcctc cagggtcccc taacccaacg cccttgttgt aaatgaggta     4920

actgaggctc agggaggcac tgtgagccag gaatggattt tcttgaaaca gctctagctg     4980

caggttctcc gaggtaggtg cagggaatgg tgagtgtcta accagggcta catccagcaa     5040

catcctcaag gtcttcctga caaccaaaga caagccttta tggaaaagga aatgcgctcc     5100

cctccatgtt cagggatgag gggagcagca gcagccacac tcccaccatc ctcacagaat     5160

tcctggaccc atgcggtggc tccgtgagct gggtgactcc agcctcacct gcacacccca     5220

gccctgcacg gggccctcct tcctcccagc agcccttggt gagctaggaa ttgagatccc     5280

tgtttgtgaa agagggaact gaggtgcaga gaagccagag gtgtgccaga tccttaggca     5340

ggatttagat gaagtcgccc tggctccaga ctgaccccga ggctctgcgg ggagtttcca     5400

ggcagcagga agtggccttg gatgctctcc ttccaggaca gcataacccc tgggccatgt     5460

gcagctcctt cactgccccc tggatcccca gcataccccc aaagacagtg gggaaacaca     5520

aggggagagc acagcatggc ccctccagcc cacttcaggg cactcttgta tcacccgggt     5580

accgccacac tggtccccca cccagccagc atctcccagc acagcccctc tccctgggga     5640

aatgctctgg gtagccagtc taaaggcaga ggcacctaac tgctccccgc agcccacccc     5700

acccaagatt cagacacaag ccaggaaagg acccaagaga aaatccttca aggtggcctg     5760

aggtcccatc cctccctcag acccatgtgg tcccaggcca ggctgcctgg gacacggtaa     5820

ataccactgt gtgcaaaaat cgaagtacaa aaccacaaga ctaaacaaaa caaacccaga     5880

gagccaaact tgtagaggtg ggcagtccag aaagcagggg gcagccctcc ccctttcctt     5940

ctctccctga tcctcagaat atatattgtt gtaataggaa gcatttttgc attgttctct     6000

tgtgggtgtc actacagaca tgttctggcg tgttctccga gggatggagc atcctgttat     6060

atatttgact tcaaattgag atgttggctt catttttttt ttttacccaa ttaatctccc     6120

aatccctagc aactgtgact ctgtatttag cacaagagaa agctgagaat gtgggtcttg     6180

cctccttcca gaaatatgtc tggctcatca ggacattttt ttaaaacttc aaaatatttt     6240

taagatattt taaactttta taaaaaaaaa atcaaccaac aagagacttt tctgaggagg     6300

aacatttgta tttgaacaag atccttggtg tgtagttcag tcttgcagta tacaagcttt     6360

tgtgtataaa tgttttatga tatgattccc tgtattttgc aggggttttt ttctcttttg     6420

ctttttagat aaatatgtat atcaatattt taaattcatc tttgcttttt ttagaggagt     6480

ttgtaatcac cttataacat gaaaataaac atttcctttt taacatccaa aaaaaaaaaa     6540

aaaaaa                                                                6546


<210>  873
<211>  6542
<212>  DNA
<213>  homo sapiens

<400>  873
atttttccac ccagcaggat gggtgatgct gagagctgcc tgctcagaca acagacacgc       60

gaggtcagga agaagccgct tataaattac cgcttccttc gcgccgccgc caacgccgag      120

ccccgaggac cgcaagccca gaggacaagc tgcgccaaga gggagtgcgg agcgttcacc      180

cagcgggtca gagagcgagc gggcaggcag cccccggccg gcggaacccg gcacagccga      240

gcagagcgcg ggcggcgccg cagccacccc agatccagaa ccagaaccac agcccttctg      300

aggagctccc aaaccaagga gatggccacc aaggagaagc tgcagtgtct gaaagatttc      360

cacaaggaca tcctgaagcc ctcaccaggg aagagcccag gcacgcggcc tgaggacgag      420

gctgagggaa aacctccgca gagggagaag tggtctagca agatcgactt tgtgctctct      480

gtggctggcg gcttcgtggg cttgggcaac gtctggcgct tcccgtacct ctgctacaag      540

aatggtggag gtgcgtttct cataccgtat tttattttcc tgtttgggag cggcctgcct      600

gtgtttttct tggagatcat cataggccag tacacctctg aagggggcat cacctgctgg      660

gaaaagatct gccccttgtt ctctggtatc ggctatgcct ccgttgtaat tgtgtccctc      720

ctgaatgtct actacatcgt catcctggcc tgggccacat actacctgtt ccagtccttc      780

cagaaggagc tgccctgggc acactgcaac cacagctgga acacacctca ctgcatggag      840

gacaccatgc gcaagaacaa gagtgtctgg atcaccatca gctccaccaa cttcacctcc      900

cctgtcatcg agttctggga gcgcaacgtg ctgagcttgt cccctggaat cgaccaccca      960

ggctctctga aatgggacct cgctctctgc cttcttttag tctggctagt gtgtttcttc     1020

tgcatctgga agggcgtcag gtccactggg aaggtcgtct acttcacagc cacttttcca     1080

ttcgccatgc tcctggtgct gctggtccga gggctgacgc tgccgggcgc gggcgcaggc     1140

atcaagttct atctgtatcc tgacatcacc cgccttgagg acccacaggt gtggattgac     1200

gctgggactc agatattctt ctcttatgcc atctgcctgg gggctatgac ctcgctgggg     1260

agctacaaca agtacaagta taactcgtac agggactgta tgctgctggg atgcctgaac     1320

agtggtacca gttttgtgtc tggcttcgca attttttcca tcctgggctt catggcacaa     1380

gagcaagggg tggacattgc tgatgtggct gagtcaggtc ctggcctggc cttcattgcc     1440

tacccaaaag ctgtgacaat gatgccgctg cccacatttt ggtccattct tttttttatt     1500

atgcttctct tgcttggact ggatagccag tttgttgaag ttgaaggaca gatcacatcc     1560

ttggttgatc tttacccatc cttcctaagg aagggttatc gtcgggaaat cttcatcgcc     1620

ttcgtgtgta gcatcagcta cctgctgggg ctgacgatgg tgacggaggg tggcatgtat     1680

gtgtttcagc tctttgacta ctatgcagct agcggtgtat gccttttgtg ggttgcattc     1740

tttgaatgtt ttgttattgc ctggatatat ggaggtgata acctttatga tggtattgag     1800

gacatgattg gctatcggcc cgggccctgg atgaagtaca gctgggctgt gatcactcca     1860

gttctctgtg ttggatgttt catcttctcg ctcgtcaagt acgtacccct gacctacaac     1920

aaaacatacg tgtaccccaa ctgggccatt gggctgggct ggagcctggc cctttcctcc     1980

atgctctgcg ttcccttggt catcgtcatc cgcctctgcc agactgaggg gccgttcctt     2040

gtgagagtca agtacctgct gaccccaagg gaacccaacc gctgggctgt ggagcgcgag     2100

ggagccacac cttacaactc tcgcaccgtc atgaacggcg ctctcgtgaa accgacccac     2160

atcattgtgg agaccatgat gtgagctctc tcgggtcgac ggggccggcg gctttcctgc     2220

tgtttactaa cattagattc tcataggacc aggtttacag agctttatat ttgcactagg     2280

attttttttt ttttgtaatt gtcacagaaa atgtaattgt gggtatgtgt gcgtgcgtgt     2340

gtgtgtgtgt gtgtatcgtg tgtgtgtgtt ttgttttgat ttgggggata ttttgtacaa     2400

aaagaaaacc cacgggaaga tgtccgtgga gaggcagagc tttcatactg aattagatgt     2460

attttatggg aatttggtaa atttttcttt gtattttttt ttttacatat aagtatatat     2520

acacttagag attgtcatat acttttacca cttgaattga tcttcttgcc agcaatagat     2580

ctcattttca aaagcaattc ttcggtgctg tgtagctggc agaaagttct gtccagtaaa     2640

cgcaggatgg aattttcctg ggactctaca cccatcttaa ggtggtatac cttccaaatc     2700

ctggttcaga tggaagaaat agcaggagag aggacccatt agctggcaga cccaggggga     2760

agaaaggagg gctgtgagga gatacctcat taaacttggc ttagtgaaga agagagatgc     2820

caaaggaatg aaccaaccct tcacataaag gagactggct gaagctgaat gaggaggccc     2880

tatagcagaa gtctgattct aagagcagta gaaacttgta ccagaagcaa aatcccactt     2940

ttaattttga gatggtgagt ggatagtcag tagaccgtca gaaccactgg ccagagaggg     3000

agctgctaga gatccaagaa ggctggcagg agtgaggctc acaactcagc ctcgcaagag     3060

gtggcagagg cacaggaggc cacagtcctt cctggggcat tccaggcaga gaaggagcag     3120

aggctctccc ggcaggagct ggggtctcag ggctcagatg agtctgttgc atttgaatgg     3180

ggtcatagca ggttctggtc attccccaag caacatctca gcatctctta aagttgcctg     3240

caggaatgaa gcatgacata cctgttgagg gactagggga gtggtgggga ggtgagtgga     3300

ccaaaggata taggccccag gcatgcagat gggcccggtg tcggggaggg gtgctttctt     3360

tcctcatctc cccactcccc actctcagcc tgggagactc ctgccaagcc ctcattaaag     3420

atgccaccct gggctgccct ggcacctagc aaggcacacc aagaacagct tttgagtctg     3480

tatcctccac tgggggaagt gctcccagtt cagaacaagg gcagcccgtg gtgctgacct     3540

aggatataac aaagctcttc acttcaaaac ccctgcaata gctgggttta cagacattta     3600

ccacctgcgg acccaaaaga gaaggcctag gagagttttc tagaaggttg ggattgtcag     3660

ggtcctggcc cctcagaact ggcttgatca agggccttat gtggagcaga ggttgtctct     3720

gaaccaggag agaaggtact atacctttca aatccccagg gcagacacac ccccacccag     3780

cccctatttg gacctaaact gtgccatttg aacagtcact tccaagctca gtctaaatga     3840

aaccgaaacg tgaccacgca caaaggcagt cactgcctcg aggggtgcag accgcagaat     3900

tttcacagca ggggctcttg gaaccctgga aacccccttc ttaaatttgg gaggaggagt     3960

atgcctttgg tgtccccctc ccaaggggca attctgaacc ccatctttgg caggcataca     4020

tatttcactg tttccaaagc tatctactct gccaaacaac acccagtcct attccaaact     4080

ctcaacgatt ctatcttgtt cctgtttttc tatgtattta tggttgccgt ttgtgtctga     4140

tttgatttta ctgttttttc cctgatttta tggagtagca ttgtgacctg ttttcctttg     4200

tcttatataa ctttagtaaa ctaaccactg tcaatgattg agggcaggtg gcacgtgggg     4260

aagaggggac ttggcacgca gtggctacct gggcatttgt ggtcatttca gtttccatct     4320

ccccagcggg ggctccctgg gtgaaaggcc acagtatttt gggttggtag gcaaattgca     4380

acattctgga catggcctga ggaaggcctc ttcttataag attctcagac caaattctag     4440

accaaagaca caggcagacc aagtccccag gccccgcctg gaaggaagtc gttcctcaac     4500

tctccccaag gcacctgtct ccaatcagag ccctctcgcc cagccagccc tggctctgtg     4560

tgcagagcat agctctgcga gtacctgtgt aataatgctc aaccttcatg tctccgtata     4620

aacgaaactt tccatgagag ctcatgactc tggtccacct gtctatagag aatgggcaaa     4680

gtccttcacc tgctttctgc ttgggatggg tcagaaatgc tgatgcccgc acatagccca     4740

gccagccaga tctggaaagg aagcgagggg gttgtttaaa tcaatttttt aagatgaaga     4800

agtgggagac actgcgttga gatgggccat gctagggcca cagagatttc ctgacggtca     4860

gggagagaag ggcctccagg gtcccctaac ccaacgccct tgttgtaaat gaggtaactg     4920

aggctcaggg aggcactgtg agccaggaat ggattttctt gaaacagctc tagctgcagg     4980

ttctccgagg taggtgcagg gaatggtgag tgtctaacca gggctacatc cagcaacatc     5040

ctcaaggtct tcctgacaac caaagacaag cctttatgga aaaggaaatg cgctcccctc     5100

catgttcagg gatgagggga gcagcagcag ccacactccc accatcctca cagaattcct     5160

ggacccatgc ggtggctccg tgagctgggt gactccagcc tcacctgcac accccagccc     5220

tgcacggggc cctccttcct cccagcagcc cttggtgagc taggaattga gatccctgtt     5280

tgtgaaagag ggaactgagg tgcagagaag ccagaggtgt gccagatcct taggcaggat     5340

ttagatgaag tcgccctggc tccagactga ccccgaggct ctgcggggag tttccaggca     5400

gcaggaagtg gccttggatg ctctccttcc aggacagcat aacccctggg ccatgtgcag     5460

ctccttcact gccccctgga tccccagcat acccccaaag acagtgggga aacacaaggg     5520

gagagcacag catggcccct ccagcccact tcagggcact cttgtatcac ccgggtaccg     5580

ccacactggt cccccaccca gccagcatct cccagcacag cccctctccc tggggaaatg     5640

ctctgggtag ccagtctaaa ggcagaggca cctaactgct ccccgcagcc caccccaccc     5700

aagattcaga cacaagccag gaaaggaccc aagagaaaat ccttcaaggt ggcctgaggt     5760

cccatccctc cctcagaccc atgtggtccc aggccaggct gcctgggaca cggtaaatac     5820

cactgtgtgc aaaaatcgaa gtacaaaacc acaagactaa acaaaacaaa cccagagagc     5880

caaacttgta gaggtgggca gtccagaaag cagggggcag ccctccccct ttccttctct     5940

ccctgatcct cagaatatat attgttgtaa taggaagcat ttttgcattg ttctcttgtg     6000

ggtgtcacta cagacatgtt ctggcgtgtt ctccgaggga tggagcatcc tgttatatat     6060

ttgacttcaa attgagatgt tggcttcatt tttttttttt acccaattaa tctcccaatc     6120

cctagcaact gtgactctgt atttagcaca agagaaagct gagaatgtgg gtcttgcctc     6180

cttccagaaa tatgtctggc tcatcaggac atttttttaa aacttcaaaa tatttttaag     6240

atattttaaa cttttataaa aaaaaaatca accaacaaga gacttttctg aggaggaaca     6300

tttgtatttg aacaagatcc ttggtgtgta gttcagtctt gcagtataca agcttttgtg     6360

tataaatgtt ttatgatatg attccctgta ttttgcaggg gtttttttct cttttgcttt     6420

ttagataaat atgtatatca atattttaaa ttcatctttg ctttttttag aggagtttgt     6480

aatcacctta taacatgaaa ataaacattt cctttttaac atccaaaaaa aaaaaaaaaa     6540

aa                                                                    6542


<210>  874
<211>  1316
<212>  DNA
<213>  homo sapiens

<400>  874
atttttccac ccagcaggat gggtgatgct gagagctgcc tgctcagaca acagacacgc       60

gaggtcagga agaagccgct tataaattac cgcttccttc gcgccgccgc caacgccgag      120

ccccgaggac cgcaagccca gaggacaagc tgcgccaaga gggagtgcgg agcgttcacc      180

cagcgggtca gagagcgagc gggcaggcag cccccggccg gcggaacccg gcacagccga      240

gcagagcgcg ggcggcgccg cagccacccc agatccagaa ccagaaccac agcccttctg      300

aggagctccc aaacaaagca aggagatggc caccaaggag aagctgcagt gtctgaaaga      360

tttccacaag gacatcctga agccctcacc agggaagagc ccaggcacgc ggcctgagga      420

cgaggctgag ggaaaacctc cgcagaggga gaagtggtct agcaagatcg actttgtgct      480

ctctgtggct ggcggcttcg tgggcttggg caacgtctgg cgcttcccgt acctctgcta      540

caagaatggt ggaggtgcgt ttctcatacc gtattttatt ttcctgtttg ggagcggcct      600

gcctgtgttt ttcttggaga tcatcatagg ccagtacacc tctgaagggg gcatcacctg      660

ctgggaaaag atctgcccct tgttctctgg tatcggctat gcctccgttg taattgtgtc      720

cctcctgaat gtctactaca tcgtcatcct ggcctgggcc acatactacc tgttccagtc      780

cttccagaag gagctgccct gggcacactg caaccacagc tggaacacac ctcactgcat      840

ggaggacacc atgcgcaaga acaagagtgt ctggatcacc atcagctcca ccaacttcac      900

ctcccctgtc atcgagttct gggagtaagg ccacctcatt gaagcaagga ggaggacatg      960

ggtggggcag agaggatggc ccacttcctt atctcctccc ctgggataca ggagccactg     1020

tcttcggggg agtgggagga gggtgcagat ctggagataa atttatgcct ttggccatag     1080

acaggactgg aatcccagtt ctgccactta ctggctgttt gaccttaggc aagccactcc     1140

tcctttctga gcctcagttt ctttacctgt aagataaaaa gaatgaatca ttactaccct     1200

gtgaggcagg tatgcatact tatgttgtct aaaaatgata cagttttctt aatgtatttt     1260

aggaaaaaat atattctgtt attgcacaga gaaaaaaaaa aaaaaaaaaa aaaaaa         1316


<210>  875
<211>  3550
<212>  DNA
<213>  homo sapiens

<400>  875
gccgggcccc gccgccgccc gcgcgccccc gggcccccga cacacatgag attcttcagg       60

ctcactttca agtgcttcgt ggactgcttc tgactgcgcc gcccgcgccc cgcaccccgc      120

cgcccgcccg ccgccccgtc ccccggcccg gccgcccccc ggcccccggc cggcccgcgc      180

cctcggggcc ctccccggtg ccgccggtgc cccccgcctg accgccgccc cccgtgaggc      240

gccgcgaccc cggcccggcc gtgcggcccg ccgaggccat ggcgaagaag agcgccgaga      300

acggcatcta tagcgtgtcc ggcgacgaga agaagggccc cctcatcgcg cccgggcccg      360

acggggcccc ggccaagggc gacggccccg tgggcctggg gacacccggc ggccgcctgg      420

ccgtgccgcc gcgcgagacc tggacgcgcc agatggactt catcatgtcg tgcgtgggct      480

tcgccgtggg cttgggcaac gtgtggcgct tcccctacct gtgctacaag aacggcggag      540

gtgtgttcct tattccctac gtcctgatcg ccctggttgg aggaatcccc attttcttct      600

tagagatctc gctgggccag ttcatgaagg ccggcagcat caatgtctgg aacatctgtc      660

ccctgttcaa aggcctgggc tacgcctcca tggtgatcgt cttctactgc aacacctact      720

acatcatggt gctggcctgg ggcttctatt acctggtcaa gtcctttacc accacgctgc      780

cctgggccac atgtggccac acctggaaca ctcccgactg cgtggagatc ttccgccatg      840

aagactgtgc caatgccagc ctggccaacc tcacctgtga ccagcttgct gaccgccggt      900

cccctgtcat cgagttctgg gagaacaaag tcttgaggct gtctggggga ctggaggtgc      960

caggggccct caactgggag gtgacccttt gtctgctggc ctgctgggtg ctggtctact     1020

tctgtgtctg gaagggggtc aaatccacgg gaaagatcgt gtacttcact gctacattcc     1080

cctacgtggt cctggtcgtg ctgctggtgc gtggagtgct gctgcctggc gccctggatg     1140

gcatcattta ctatctcaag cctgactggt caaagctggg gtcccctcag gtgtggatag     1200

atgcggggac ccagattttc ttttcttacg ccattggcct gggggccctc acagccctgg     1260

gcagctacaa ccgcttcaac aacaactgct acaatgggac cagcttcttt gctggcttcg     1320

tggtcttctc catcctgggc ttcatggctg cagagcaggg cgtgcacatc tccaaggtgg     1380

cagagtcagg gccgggcctg gccttcatcg cctacccgcg ggctgtcacg ctgatgccag     1440

tggccccact ctgggctgcc ctgttcttct tcatgctgtt gctgcttggt ctcgacagcc     1500

agtttgtagg tgtggagggc ttcatcaccg gcctcctcga cctcctcccg gcctcctact     1560

acttccgttt ccaaagggag atctctgtgg ccctctgttg tgccctctgc tttgtcatcg     1620

atctctccat ggtgactgat ggcgggatgt acgtcttcca gctgtttgac tactactcgg     1680

ccagcggcac caccctgctc tggcaggcct tttgggagtg cgtggtggtg gcctgggtgt     1740

acggagctga ccgcttcatg gacgacattg cctgtatgat cgggtaccga ccttgcccct     1800

ggatgaaatg gtgctggtcc ttcttcaccc cgctggtctg catgggcatc ttcatcttca     1860

acgttgtgta ctacgagccg ctggtctaca acaacaccta cgtgtacccg tggtggggtg     1920

aggccatggg ctgggccttc gccctgtcct ccatgctgtg cgtgccgctg cacctcctgg     1980

gctgcctcct cagggccaag ggcaccatgg ctgagcgctg gcagcacctg acccagccca     2040

tctggggcct ccaccacttg gagtaccgag ctcaggacgc agatgtcagg ggcctgacca     2100

ccctgacccc agtgtccgag agcagcaagg tcgtcgtggt ggagagtgtc atgtgacaac     2160

tcagctcaca tcaccagctc acctctggta gccatagcag cccctgcttc agccccaccg     2220

cacccctcca gggggcctgc ctttccctga cacttttggg gtctgcctgg gggaggaggg     2280

gagaaagcac catgagtgct cactaaaaca actttttcca tttttaataa aacgccaaaa     2340

atatcacaac ccaccaaaaa tagatgcctc tccccctcca gccctagccg agctggtcct     2400

aggccccgcc tagtgcccca cccccaccca cagtgctgca ctcctcctgc ccctgccacg     2460

cccaccccct gcccacctct ccaggctctg ctctgcagca cacccgtggg tgacccctca     2520

ccccagaagc agcagtggca gcttgggaaa tgtgaggaag ggaaggaggg agagacggga     2580

gggaggagag agaggagaag ggaggcaggg gaggggcagc agaaccaagg caaatatttc     2640

agctgggcta tacccctctc cccatccctg ttatagaagc ttagagagcc agccagcaat     2700

ggaaccttct ggttcctgcg ccaatcgcca ccagtatcaa ttgtgtgagc ttgggtgcga     2760

gtgcacgcgt gcgtgagtac ggagagtata tatagatctc tatctcttag caaaggtgaa     2820

tgccagatgt aaatggcgcc tctgggcaaa ggaggcttgt attttgcaca ttttataaaa     2880

acttgagaga atgagatttc tgcttgtata tttctaaaaa gaggaaggag cccaaaccat     2940

cctctcctta ccactcccat ccctgtgagc cctaccttac ccctctgccc ctagccaagg     3000

agtgtgaatt tatagatcta actttcatag gcaaaacaaa agcttcgagc tgttgcgtgt     3060

gtgagtctgt tgtgtggatg tgcgtgtgtg gtccccagcc ccagactgga ttggaaaagt     3120

gcatggtggg ggcctcgggg ctgtccccac gctgtccctt tgccacaagt ctgtggggca     3180

agaggctgca atattccgtc ctgggtgtct gggctgctaa cctggcctgc tcaggcttcc     3240

caccctgtgc ggggcacacc cccaggaagg gaccctggac acggctccca cgtccaggct     3300

taaggtggat gcacttcccg cacctccagt cttctgtgta gcagctttaa cccacgtttg     3360

tctgtcacgt ccagtcccga gacggctgag tgaccccaag aaaggcttcc ccgacaccca     3420

gacagaggct gcagggctgg ggctgggtga gggtggcggg cctgcgggga cattctactg     3480

tgctaaaaag ccactgcaga catagcaata aaaacatgtc attttccaaa gcaggaaaaa     3540

aaaaaaaaaa                                                            3550


<210>  876
<211>  1535
<212>  DNA
<213>  homo sapiens

<400>  876
ccgtgcaccg tgtgtgcgcg cggcgttgaa atgccctgca cgtcggggca gcgggacaga       60

tcccagggtg cccagggagt ctccaagtgc ctcactcctc ccgccgcaaa catgacagag      120

aactccgaca aagttcccat tgccctggtg ggacctgatg acgtggaatt ctgcagcccc      180

ccggcgtacg ctacgctgac ggtgaagccc tccagccccg cgcggctgct caaggtggga      240

gccgtggtcc tcatttcggg agctgtgctg ctgctctttg gggccatcgg ggccttctac      300

ttctggaagg ggagcgacag tcacatttac aatgtccatt acaccatgag tatcaatggg      360

aaattacaag atgggtcaat ggaaatagac gctgggaaca acttggagac ctttaaaatg      420

ggaagtggag ctgaagaagc aattgcagtt aatgatttcc agaatggcat cacaggaatt      480

cgttttgctg gaggagagaa gtgctacatt aaagcgcaag tgaaggctcg tattcctgag      540

gtgggcgccg tgaccaaaca gagcatctcc tccaaactgg aaggcaagat catgccagtc      600

aaatatgaag aaaattctct tatctgggtg gctgtagatc agcctgtgaa ggacaacagc      660

ttcttgagtt ctaaggtgtt agaactctgc ggtgaccttc ctattttctg gcttaaacca      720

acctatccaa aagaaatcca gagggaaaga agagaagtgg taagaaaaat tgttccaact      780

accacaaaaa gaccacacag tggaccacgg agcaacccag gcgctggaag actgaataat      840

gaaaccagac ccagtgttca agaggactca caagccttca atcctgataa tccttatcat      900

caggaagggg aaagcatgac attcgaccct agactggatc acgaaggaat ctgttgtata      960

gaatgtaggc ggagctacac ccactgccag aagatctgtg aacccctggg gggctattac     1020

ccatggcctt ataattatca aggctgccgt tcggcctgca gagtcatcat gccatgtagc     1080

tggtgggtgg cccgtatctt gggcatggtg tgaaatcact tcatatatca tgtgctgtaa     1140

aataagaact agctgaagag acaaccaaag aagcattaag gcaggttgat gctgatggga     1200

ccataaaata tttttacact caacctgagc ggttattctt gacactctta acagaatttt     1260

ttcaattgtt ttccagaact ttagtatatg caaatgtact gaaagggtag ttcaagtcta     1320

aaatgccata acccctttat tatttgttat tttttatttg cattgctttg ccataagtct     1380

tcccttgctt gtatcttcca aagctatttt gaaataaaca tgaaaattta cagtttgcca     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                                1535


<210>  877
<211>  1538
<212>  DNA
<213>  homo sapiens

<400>  877
ccgtgcaccg tgtgtgcgcg cggcgttgaa atgccctgca cgtcggggca gcgggacaga       60

tcccagggtg cccagggagt ctccaagtgc ctcactcctc ccgccgcaaa catgacagag      120

aactccgaca aagttcccat tgccctggtg ggacctgatg acgtggaatt ctgcagcccc      180

ccggcgtacg ctacgctgac ggtgaagccc tccagccccg cgcggctgct caaggtggga      240

gccgtggtcc tcatttcggg agctgtgctg ctgctctttg gggccatcgg ggccttctac      300

ttctggaagg ggagcgacag tcacatttac aatgtccatt acaccatgag tatcaatggg      360

aaattacaag atgggtcaat ggaaatagac gctgggaaca acttggagac ctttaaaatg      420

ggaagtggag ctgaagaagc aattgcagtt aatgatttcc agaatggcat cacaggaatt      480

cgttttgctg gaggagagaa gtgctacatt aaagcgcaag tgaaggctcg tattcctgag      540

gtgggcgccg tgaccaaaca gagcatctcc tccaaactgg aaggcaagat catgccagtc      600

aaatatgaag aaaattctct tatctgggtg gctgtagatc agcctgtgaa ggacaacagc      660

ttcttgagtt ctaaggtgtt agaactctgc ggtgaccttc ctattttctg gcttaaacca      720

acctatccaa aagaaatcca gagggaaaga agagaagtgg taagaaaaat tgttccaact      780

accacaaaaa gaccacacag tggaccacgg agcaacccag gcgctggaag actgaataat      840

gaaaccagac ccagtgttca agaggactca caagccttca atcctgataa tccttatcat      900

cagcaggaag gggaaagcat gacattcgac cctagactgg atcacgaagg aatctgttgt      960

atagaatgta ggcggagcta cacccactgc cagaagatct gtgaacccct ggggggctat     1020

tacccatggc cttataatta tcaaggctgc cgttcggcct gcagagtcat catgccatgt     1080

agctggtggg tggcccgtat cttgggcatg gtgtgaaatc acttcatata tcatgtgctg     1140

taaaataaga actagctgaa gagacaacca aagaagcatt aaggcaggtt gatgctgatg     1200

ggaccataaa atatttttac actcaacctg agcggttatt cttgacactc ttaacagaat     1260

tttttcaatt gttttccaga actttagtat atgcaaatgt actgaaaggg tagttcaagt     1320

ctaaaatgcc ataacccctt tattatttgt tattttttat ttgcattgct ttgccataag     1380

tcttcccttg cttgtatctt ccaaagctat tttgaaataa acatgaaaat ttacagtttg     1440

ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                             1538


<210>  878
<211>  4806
<212>  DNA
<213>  homo sapiens

<400>  878
tccggaggcg agccgagcgc ggtggtgagg ccgcctcagc gaaaaaaatg tccgcctgaa       60

gagacccaca agttctattc ggggggaccg acagcccgcc ccgggaggaa ggggcggcca      120

ggcccgaaag ccgcctcccc ctcccagacc cgagagctcg tgcggggcaa agtgaaccga      180

gccgctgggc ggtgcaaggg gaagcccaag cccgttctcc cggccaaagt gaactttaat      240

cggggtggtt ggatgcggag acggggcggc aggacctgct agaagtggcc gaagatgaat      300

ccccagcaac aacgcatggc cgctataggg accgacaagg agctgagcga cctactggac      360

ttcagtgcga tgttttcccc acctgttaat agtgggaaaa ctagaccaac tacactggga      420

agcagtcaat tcagtggatc aggtattgat gaaagaggag gtacaacatc ttggggaaca      480

agtggtcaac caagtccttc ctatgattca tctagaggtt ttacagacag ccctcattac      540

agtgatcact tgaatgacag tcgattagga gcccatgaag gcttgtcccc aacacctttc      600

atgaactcaa atctgatggg aaaaacatca gagagaggct cattttccct gtacagcaga      660

gatactggat taccaggctg tcaatctagt ctcctgagac aagatctggg gcttgggagc      720

ccagcacagc tatcttcttc aggaaaacct gggacagcat actattcatt ctctgctaca      780

agttccagga ggagaccact ccatgactct gcagcgcttg atcccttgca agcaaaaaaa      840

gtcagaaagg tgcctcctgg tttgccttct tctgtatatg caccatcccc aaattcagat      900

gatttcaacc gtgaatctcc tagttatcca tctcctaagc caccaaccag tatgttcgct      960

agcactttct ttatgcaaga tgggacccac aattcttctg acctttggag ttcatcaaat     1020

gggatgagcc agcctggttt tggtggaatt ctggggacct ccacttccca catgtctcaa     1080

tccagtagtt atggcaacct tcattcacat gaccgcttga gttatcctcc acactcagtt     1140

tcaccaacag acataaacac gagtcttcca ccaatgtcca gctttcatcg cggcagtacc     1200

agcagttcac cttacgttgc tgcctcacac actcctccca tcaatggatc agacagcatt     1260

ctaggaacca gagggaatgc tgctggaagc tcacagacag gtgatgcact tggaaaggct     1320

ttggcatcta tttattctcc tgaccatacc agcagtagtt ttccgtcaaa tccatcaaca     1380

ccagttggat caccttcacc tctcacaggt accagtcagt ggccaagacc tggagggcaa     1440

gcaccttcat ccccaagcta tgaaaactca ctccactccc tgaaaaatcg agttgagcag     1500

caacttcacg agcatttgca agatgcaatg tccttcttaa aggatgtctg tgagcagtct     1560

cgaatggagg atcgtttaga cagactggat gatgcaatcc atgtgctgcg gaaccatgct     1620

gtgggacctt ccaccagttt gcctgctggt cacagtgata tacatagttt attgggacca     1680

tcccataatg caccaattgg aagcctcaat tcaaactatg gaggatcaag ccttgttgca     1740

agcagtcgat cagcttcaat ggttggaact catcgggaag actctgtcag tctcaatggc     1800

aatcattcag tcctgtctag tacagtcact acttcaagca cagacctgaa ccataaaaca     1860

caagaaaatt atagaggtgg cttgcaaagt cagtctggaa ctgttgttac aacagaaatc     1920

aagactgaaa acaaagaaaa ggatgaaaac cttcatgaac ctccttcatc agatgacatg     1980

aagtcagatg atgaatcctc ccaaaaagat atcaaggttt catctagagg cagaacaagc     2040

agtactaatg aagatgagga tttgaaccct gaacagaaga tagaaaggga gaaggagagg     2100

cggatggcta acaatgccag agaacgctta cgcgtgcggg atattaatga agcattcaaa     2160

gagcttggcc gaatgtgtca gcttcacttg aagagtgaaa aaccccaaac aaaactcctt     2220

attcttcatc aagccgtggc agtcatcctt agtctagaac agcaagtcag agagaggaac     2280

cttaacccca aagcagcctg ccttaagaga agggaagaag aaaaagtttc tgccgtatcg     2340

gcagagccgc caaccacact gccaggaacc catcctgggc ttagtgaaac taccaaccct     2400

atgggtcata tgtaaacatc agccagttcc agagttatca gtaggctaga tagaaggtga     2460

cctctcctca taaggacttg gacaactcag attatctgaa gacacaaacc tgacaggagg     2520

gagaagaaaa aacaaaacac ttgaaccaag aaactcaaat gtaatcctac gatcaaagca     2580

actggtcaac acttccatca gaagtgaaga taggaagctc atcagataga acatcagccc     2640

atgagatgtt tgcaacaaat cttttgttgc aagcagtgtg tcgcttctgc acaatcagag     2700

actgtctcga tctctccact caccgtggaa gttgccttgt gcctaaactg aattgacaaa     2760

tgcattgtaa ctacaaattt tatttattgt tatgaaactg taaggtctac atataaaggg     2820

aaaaagttaa tgtggaaagc tgatctacac tcagctgatg ccagcataca ttaaagcggt     2880

tcacgtgcag agaacaaagc agtgacaacc attggccctt agcattcccg gcatacctat     2940

tagtgtctta aaaaggaagg gaaaagtctt ttgttgccct ctcctatcct cttgccatat     3000

gaatagcgtt ttccatgaaa taggaaaata ttacttggta tagcatttct cttgctctca     3060

ttttttgatt tatttttatt ttctctttgt gggtgttata tttgatctct aaatctgaac     3120

agtttatggt cacagtccag cctcctccgt gcagccctgt gtgctttgca catttacctt     3180

acagtggtaa gcagagacca tctgtgacca tagcctagct agcattttaa aaggggaaat     3240

tttgttctct aggttttccc ccaaataaac attgctttat ttctaataat aaccaagact     3300

tttcaagctt ctagatctca taggaaagct tgtaatagca aaattgtaaa ttacaaggga     3360

agaatctact ttttagaaat cgctttgttt tccaagcagt aagtactaca tacagtactt     3420

gtaaagtgtt agctgtaagt aagcacaaaa tacatttaaa atacaaagac gattttttca     3480

ggctgtgatt atggtgaaca taacaaaacc cagtagtcac caaggcaggt agtgtgataa     3540

atgaacacac cactctgagg ctaattacct aatggaatac aagagcaatg gtcacccgta     3600

tttccttatc ctagccttta tttctctgtc atttggatgg ctggtcaatg gggaagaatt     3660

gagtgggtga tttaatcaac tgcaaaccat ctgcccctgt cccaaaatga tgagccagat     3720

tagcattaaa ccagtacttg tcagtccatc ttaatactgt tcattaaggc actctctgtc     3780

tctaatcctt aggagttgtt ttaaaagaca taatcacttt gaacttccat gaaacctgtc     3840

ttccaccaca acaaccctgg gagagaaaaa catgctaaag gaggtatctt ggcttaataa     3900

ttccttatag ccaatatcaa cagtggcaat cagcacacag aggaaaggac ccaaatcact     3960

atgtagctta aagatttctg ttaatttgaa agaacaaaaa caagacagaa cttctggtac     4020

tctaatcagg atgattccta acaagtcagt catttgtgaa cttagtggac tttttggtta     4080

ctttaatttg catatattct ccagttacat cggactctat ctgtggcctt gttcttcatt     4140

tcagtgttaa tcagctaaac agaagttgtt gcttatgatg tgtgagtgaa catatgccac     4200

tgcctggcct ttttttcttc agagcttgtt gtctttttcg ctatattaga ctttgcagta     4260

tgcccagaag ctttccttca taaaatagaa agaaaaaaac atttggctta tttttcactg     4320

tagctagtct tttatacaat aatcttgtaa gaaaatttct tgaattctaa atattactct     4380

ttctagattt ttgaaatcaa aaagttttca gtaaaaagtt tcttacttta ttttattata     4440

ttaggtagta aaaaatgtag ggttatttac cataacctgt tcattaatat cagaaattta     4500

caatagcatt ttaagaccat agtaggattc tagcataccg tgtagtacct atggagtatt     4560

gtaagagcta attgttggag atgaattgct tctcatcttg ttctccagtt tccattgttg     4620

gtttattgca gatttgtatc ctgtgtcaaa ttcaaggtat tattgataaa ccttttcaac     4680

cagcagcaag aagttcaaat ttttttctgt cactgtaaca gaaaacacaa tatgtatata     4740

acatttatgt agcaataaat gtgccatctt ttttttaaca cagtaaaaaa aaaaaaaaaa     4800

aaaaaa                                                                4806


<210>  879
<211>  4035
<212>  DNA
<213>  homo sapiens

<400>  879
gtgtagcgcc agcgcgctgt gacgtaatgt gaggggtctc ccggcagggc tgagctggac       60

caatgaggaa aggcaagggg ccgatttgcc tgttctcacg ccccaccctc agacctagcc      120

ggagcaaagt ttcacttata gaagggagag gagcgaacat ggcagcgcgt tggcggtttt      180

ggtgtgtctc tgtgaccatg gtggtggcgc tgctcatcgt ttgcgacgtt ccctcagcct      240

ctgcccaaag aaagaaggag atggtgttat ctgaaaaggt tagtcagctg atggaatgga      300

ctaacaaaag acctgtaata agaatgaatg gagacaagtt ccgtcgcctt gtgaaagccc      360

caccgagaaa ttactccgtt atcgtcatgt tcactgctct ccaactgcat agacagtgtg      420

tcgtttgcaa gcaagctgat gaagaattcc agatcctggc aaactcctgg cgatactcca      480

gtgcattcac caacaggata ttttttgcca tggtggattt tgatgaaggc tctgatgtat      540

ttcagatgct aaacatgaat tcagctccaa ctttcatcaa ctttcctgca aaagggaaac      600

ccaaacgggg tgatacatat gagttacagg tgcggggttt ttcagctgag cagattgccc      660

ggtggatcgc cgacagaact gatgtcaata ttagagtgat tagaccccca aattatgctg      720

gtccccttat gttgggattg cttttggctg ttattggtgg acttgtgtat cttcgaagaa      780

gtaatatgga atttctcttt aataaaactg gatgggcttt tgcagctttg tgttttgtgc      840

ttgctatgac atctggtcaa atgtggaacc atataagagg accaccatat gcccataaga      900

atccccacac gggacatgtg aattatatcc atggaagcag tcaagcccag tttgtagctg      960

aaacacacat tgttcttctg tttaatggtg gagttacctt aggaatggtg cttttatgtg     1020

aagctgctac ctctgacatg gatattggaa agcgaaagat aatgtgtgtg gctggtattg     1080

gacttgttgt attattcttc agttggatgc tctctatttt tagatctaaa tatcatggct     1140

acccatacag ctttctgatg agttaaaaag gtcccagaga tatatagaca ctggagtact     1200

ggaaattgaa aaacgaaaat cgtgtgtgtt tgaaaagaag aatgcaactt gtatattttg     1260

tattacctct ttttttcaag tgatttaaat agttaatcat ttaaccaaag aagatgtgta     1320

gtgccttaac aagcaatcct ctgtcaaaat ctgaggtatt tgaaaataat tatcctctta     1380

accttctctt cccagtgaac tttatggaac atttaattta gtacaattaa gtatattata     1440

aaaattgtaa aactactact ttgttttagt tagaacaaag ctcaaaacta ctttagttaa     1500

cttggtcatc tgattttata ttgccttatc caaagatggg gaaagtaagt cctgaccagg     1560

tgttcccaca tatgcctgtt acagataact acattaggaa ttcattctta gcttcttcat     1620

ctttgtgtgg atgtgtatac tttacgcatc tttccttttg agtagagaaa ttatgtgtgt     1680

catgtggtct tctgaaaatg gaacaccatt cttcagagca cacgtctagc cctcagcaag     1740

acagttgttt ctcctcctcc ttgcatattt cctactgaaa tacagtgctg tctatgattg     1800

tttttgtttt gttgtttttt tgagacggtc tcgctgtgtc acacaggctg gagtgcagtg     1860

gcgtgagctc ggctgactgc aaactctgcc tcccaggttt aagcgattct cctgtcacag     1920

cttcccaagt agctgggatt tacaggtgtg caccgccatg ccaggctaat ttttgtgttt     1980

ttagtagaga cagggtttcg ccaagttgtc caggctggtc ttgaactcct gggctcaagt     2040

gatccgcccg cctcagtctc ccaaagtgcg aggatgacat gtgtgagcta ccacaccagc     2100

aatgtctatg cttctcgata gctgtgaaca tgaaaagaca tctattggga gtccgaggca     2160

ggtggattgc ttgaggccag gagttagaga ccagcctggc caacaaggca aaaccccgtc     2220

tctactaaaa atatgaaaat tagctgggct tggtggctca tgcctataat cctagctact     2280

tgggaggctg aggcacgaga cttgcttaat acctgggagg cggagattgc agtgagccga     2340

gatcacgcta ctgcgctcca gcctgagtga tagagtgaga ctctgtctca aaaaaaagta     2400

tctctaaata caggattata atttctgctt gagtatggtg ttaactacct tgtatttaga     2460

aagatttcag attcattcca tctccttagt tttcttttaa ggtgacccat ctgtgataaa     2520

aatatagctt agtgctaaaa tcagtgtaac ttatacatgg cctaaaatgt ttctacaaat     2580

tagagtttgt cacttattcc atttgtacct aagagaaaaa taggctcagt tagaaaagga     2640

ctccctggcc aggcgcagtg acttacgcct gtaatctcag cactttggga ggccaaggca     2700

ggcagatcac gaggtcagga gttcgagacc atcctggcca acatggtgaa accccgtctc     2760

tactaaaaat ataaaaatta gctgggtgtg gtggcaggag cctgtaatcc cagctacaca     2820

ggaggctgag gcacgagaat cacttgaact caggagatgg aggtttcagt gagccaagat     2880

cacaccactg cactccagcc tggcaacaga gcgagactcc atctcaaaaa aaaaaaaaaa     2940

agtaagaaag aaaaggactc ccttagaatg ggaaagaaaa atcataaaat attgagctga     3000

tgcctgtata tagaaattaa gcgtttctcg aaagctgttc tatgttttgc tgttatttta     3060

gtctttattc tcttccttta ggtggagaaa caaagtacca atttgaaggg atttttttta     3120

ttttgtcttt tggtttctgt cagtagaaat aaccatatgt gctaaccaaa tttctgtgaa     3180

gaatgttttc atggttatca ttatatctaa ctataacctc ccccatagtt atgaagagta     3240

acctgaaatg ccactattgt ggaaatagga taattgtaat tgtgaaaaaa taattttaag     3300

gaaatcttac aagtattaca ttaaaaagat actatgactg ccacctgcca tttaccttct     3360

aataaccctg ccatgtggtt tgcagaaaga gatggatata gtagcctcag aagaaatatt     3420

ttatgtgggt tttttgtttt tcgttactag atttcatgga tgaggggata tggttgacct     3480

tttacttttt aatggagcag ccagtttttg ttaattactc acttgtaaat tgtgagattc     3540

tgaattcctt acctgctatt cttgtacttg tctcaggcca aatctatgct gtggttctta     3600

tgagacttgt atgaagatgc cctgatttgt acagattgac cacgggaata ctactgccat     3660

gtaatctgta tagttccaga taatttgtca tgaacattga cagaatgaca attttttgta     3720

tttgcttttt ctccctttaa gagcacattc ttctgtaagg agaaaggcag cattctggct     3780

aaaatgtgta gaaggtaatt tactacactt ataaaatagt gtgacttttg tgaaaatttt     3840

gaattagctt tcatatgaag tgccttaagt agactcttca tttacttttc tggtaatggt     3900

ttaaatatca tttgttatgc atttttaaga tacagttcag aatgacacat tgtagtggca     3960

aagataacca aatgtctggc tgtttgcttt ttgaccatat caataaactt ttacaatcta     4020

aaaaaaaaaa aaaaa                                                      4035


<210>  880
<211>  3996
<212>  DNA
<213>  homo sapiens

<400>  880
agtttctgcc aggagctaat atggcttcct tagttacacc gttctctctc ttcacctaat       60

cagcgacctt actttcccag accagactgt cgagcaggag ctaagactcc ttttcccctc      120

tgctgaccgc cactacagga gcggttgaag ccagacgacc accttgtgga gttaaactcc      180

gtaaccaggg agcaccactt ccgctgacgt cattacggcg acacgtggat ccaagatggc      240

gacggcgatg gattggttgc cgtggtcttt actgcttttc tccctgatgt gtgaaacaag      300

cgccttctat gtgcctgggg tcgcgcctat caacttccac cagaacgatc ccgtagaaat      360

caaggctgtg aagctcacca gctctcgaac ccagctacct tatgaatact attcactgcc      420

cttctgccag cccagcaaga taacctacaa ggcagagaat ctgggagagg tgctgagagg      480

ggaccggatt gtcaacaccc ctttccaggt tctcatgaac agcgagaaga agtgtgaagt      540

tctgtgcagc cagtccaaca agccagtgac cctgacagtg gagcagagcc gactcgtggc      600

cgagcggatc acagaagact actacgtcca cctcattgct gacaacctgc ctgtggccac      660

ccggctggag ctctactcca accgagacag cgatgacaag aagaaggaaa aagatgtgca      720

gtttgaacac ggctaccggc tcggcttcac agatgtcaac aagatctacc tgcacaacca      780

cctctcattc atcctttact atcatcggga ggacatggaa gaggaccagg agcacacgta      840

ccgtgtcgtc cgcttcgagg tgattcccca gagcatcagg ctggaggacc tcaaagcaga      900

tgagaagagt tcgtgcactc tgcctgaggg taccaactcc tcgccccaag aaattgaccc      960

caccaaggag aatcagctgt acttcaccta ctctgtccac tgggaggaaa gtgatatcaa     1020

atgggcctct cgctgggaca cttacctgac catgagtgac gtccagatcc actggttttc     1080

tatcattaac tccgttgttg tggtcttctt cctgtcaggt atcctgagca tgattatcat     1140

tcggaccctc cggaaggaca ttgccaacta caacaaggag gatgacattg aagacaccat     1200

ggaggagtct gggtggaagt tggtgcacgg cgacgtcttc aggccccccc agtaccccat     1260

gatcctcagc tccctgctgg gctcaggcat tcagctgttc tgtatgatcc tcatcgtcat     1320

ctttgtagcc atgcttggga tgctgtcgcc ctccagccgg ggagctctca tgaccacagc     1380

ctgcttcctc ttcatgttca tgggggtgtt tggcggattt tctgctggcc gtctgtaccg     1440

cactttaaaa ggccatcggt ggaagaaagg agccttctgt acggcaactc tgtaccctgg     1500

tgtggttttt ggcatctgct tcgtattgaa ttgcttcatt tggggaaagc actcatcagg     1560

agcggtgccc tttcccacca tggtggctct gctgtgcatg tggttcggga tctccctgcc     1620

cctcgtctac ttgggctact acttcggctt ccgaaagcag ccatatgaca accctgtgcg     1680

caccaaccag attccccggc agatccccga gcagcggtgg tacatgaacc gatttgtggg     1740

catcctcatg gctgggatct tgcccttcgg cgccatgttc atcgagctct tcttcatctt     1800

cagtgctatc tgggagaatc agttctatta cctctttggc ttcctgttcc ttgttttcat     1860

catcctggtg gtatcctgtt cacaaatcag catcgtcatg gtgtacttcc agctgtgtgc     1920

agaggattac cgctggtggt ggagaaattt cctagtctcc gggggctctg cattctacgt     1980

cctggtttat gccatctttt atttcgttaa caagctggac atcgtggagt tcatcccctc     2040

tctcctctac tttggctaca cggccctcat ggtcttgtcc ttctggctgc taacgggtac     2100

catcggcttc tatgcagcct acatgtttgt tcgcaagatc tatgctgctg tgaagataga     2160

ctgattggag tggaccacgg ccaagcttgc tccgtcctcg gacaggaagc caccctgcgt     2220

gggggactgc aggcacgcaa aataaaataa ctcctgctcg tttggaatgt aactcctggc     2280

acagtgttcc tggatcctgg ggctgcgtgg ggggcgggag ggcctgtaga taatcttgcg     2340

tttttcgtca tcttattcca gttctgtggg ggatgagttt ttttgtgggt tgctttttct     2400

tcagtgctaa gaaagttccc tccaacagga actctctgac ctgtttattc aggtgtattt     2460

ctggtttgga tttttttttc cttctttgtt ttaacaaatg gatccaggat ggataaatcc     2520

accgagataa gggttttggt cactgtctcc acctcagttc ctcagggctg ttggccaccc     2580

tatgactaac tggaagagga cacgccagag cttcagtgag gtttccgagc ctctccctgc     2640

ccatcctcac cactgaggcc acgacaaagc acagctccag ctcggacagc accctcagtg     2700

ccagccagcc tctgccagac ctctctttcc ctcttctccc cagcctcctc cagggctgcc     2760

caaggcaggg tttccagcca ggcctcgggg tcatcttttc accaggagca aacccaagtc     2820

ttagttgcta caagaaaatc ccctggaagt actgggggcc aggttcccca gacagcagga     2880

attgcccctg ttcagagcag ccggagtttg ctggaccaca aggaagaaga gaagagactt     2940

gcagtgaact gtttttgtgc caagaaaccc tggacctggg gccaagtatt tcccaagcca     3000

agcatccact tgtctgtgtc tgggaaggga tggccaaggc cgctagggtc cttacccctc     3060

aggatcactc cccagccctt tcctcaggag gtaccgctct ccaaggtgtg ctagcagtgg     3120

gccctgccca acttcaggca gaacagggag gcccagagat tacagatccc ctcctgtaag     3180

tggccaggca ttctctccct gccctctctg gcctctgggg tcatactcac ttctttagcc     3240

agccccatcc cctccacccc acacctgagt tcttgcctcc tccttttggg gacacccaaa     3300

acactgcttg tgagaaggaa gatggaaggt aagttctgtc gttctttccc caatccccag     3360

gaatggacaa gaagccaact tagaaagaag ggtctcacgt ggctggcctg gctcctccgt     3420

agacccctgt tcttttcaac ctctgcccac ccgtgcatgt catcacaaac atttgctctt     3480

aagttacaag agaccacatc cacccaggga ttagggttca agtagcagct gctaaccctt     3540

gcaccagccc ttgtgggact cccaacacaa gacaaagctc aggatgctgg tgatgctagg     3600

aagatgtccc tcccctcact gccccacatt ctcccagtgg ctctaccagc ctcacccatc     3660

aaaccagtga atttctcaat cttgcctcac agtgactgca gcgccaagcg gcatccacca     3720

agcatcaagt tggagaaaag ggaacccaag cagtagagag cgatattgga gtcttttgtt     3780

cattcaaatc ttggattttt ttttttccct aagagattct ctttttaggg ggaatgggaa     3840

acggacacct cataaagggt tcaaagatca tcaatttttc tgacttttta aatcattatc     3900

attattattt ttaattaaaa aaatgcctgt atgccttttt ttggtcggat tgtaaataaa     3960

tataccattg tcctactgaa aaaaaaaaaa aaaaaa                               3996


<210>  881
<211>  2684
<212>  DNA
<213>  homo sapiens

<400>  881
cccgctctgc ttcagcgcac gctgaagacg gcactaggac ccagggaagt ccccgagcgg       60

ggttcgcgga aaggcagcca gactcctcct tatctccagt gtcaaacttg acatcagcct      120

gcgagcggag catggtaact tctccagcaa tcagagcgct ccccctcaca tcagtggcat      180

gcttcatgga gatatgctcc tctcactgcc ctctgcacca gcaacatgga ttgtcagctc      240

tccatcctcc tccttctcag ctgctctgtt ctcgacagct tcggggaact gattccgcag      300

ccttccaatg aagtcaatct actggattca aaaacaattc aaggggagct gggctggatc      360

tcttatccat cacatgggtg ggaagagatc agtggtgtgg atgaacatta cacacccatc      420

aggacttacc aggtgtgcaa tgtcatggac cacagtcaaa acaattggct gagaacaaac      480

tgggtcccca ggaactcagc tcagaagatt tatgtggagc tcaagttcac tctacgagac      540

tgcaatagca ttccattggt tttaggaact tgcaaggaga cattcaacct gtactacatg      600

gagtctgatg atgatcatgg ggtgaaattt cgagagcatc agtttacaaa gattgacacc      660

attgcagctg atgaaagttt cactcaaatg gatcttgggg accgtattct gaagctcaac      720

actgagatta gagaagtagg tcctgtcaac aagaagggat tttatttggc atttcaagat      780

gttggtgctt gtgttgcctt ggtgtctgtg agagtatact tcaaaaagtg cccatttaca      840

gtgaagaatc tggctatgtt tccagacacg gtacccatgg actcccagtc cctggtggag      900

gttagagggt cttgtgtcaa caattctaag gaggaagatc ctccaaggat gtactgcagt      960

acagaaggcg aatggcttgt acccattggc aagtgttcct gcaatgctgg ctatgaagaa     1020

agaggtttta tgtgccaagc ttgtcgacca ggtttctaca aggcattgga tggtaatatg     1080

aagtgtgcta agtgcccgcc tcacagttct actcaggaag atggttcaat gaactgcagg     1140

tgtgagaata attacttccg ggcagacaaa gaccctccat ccatggcttg tacccgacct     1200

ccatcttcac caagaaatgt tatctctaat ataaacgaga cctcagttat cctggactgg     1260

agttggcccc tggacacagg aggccggaaa gatgttacct tcaacatcat atgtaaaaaa     1320

tgtgggtgga atataaaaca gtgtgagcca tgcagcccaa atgtccgctt cctccctcga     1380

cagtttggac tcaccaacac cacggtgaca gtgacagacc ttctggcaca tactaactac     1440

acctttgaga ttgatgccgt taatggggtg tcagagctga gctccccacc aagacagttt     1500

gctgcggtca gcatcacaac taatcaggct gctccatcac ctgtcctgac gattaagaaa     1560

gatcggacct ccagaaatag catctctttg tcctggcaag aacctgaaca tcctaatggg     1620

atcatattgg actacgaggt caaatactat gaaaagcagg aacaagaaac aagttatacc     1680

attctgaggg caagaggcac aaatgttacc atcagtagcc tcaagcctga cactatatac     1740

gtattccaaa tccgagcccg aacagccgct ggatatggga cgaacagccg caagtttgag     1800

tttgaaacta gtccagactg tatgtattat ttcaatgcag tctagaggag ggggcaggga     1860

tcttgcaaaa gatgtctgat cgtttattct cactgtttct aagttttaaa caaatgtgat     1920

acatttaagg tatattgctt gggacattgc aatttgcaga gccctgtgtc tgtatacagt     1980

atttgtgttt gtgtgggtgt acattttgtg tttctttttt tcttgtatgc aaatcaaaca     2040

tattctaatg cctgaaatgc ttctgttttt tttttttagc cataaattgc ttttgaggaa     2100

cattatttaa tatagtaaca cacttccagt gtctgtcatt tcagatattc caggttcatt     2160

gcgtgattca atgaaccaca aaaaagaaac ttgctgatcc atgagaatct taattttgtt     2220

ttaatcctta acacattcaa tagcatatca cagagagaat aaggattttc taaaatgtgt     2280

tttatcactt cattcacatt cagaagtaat ttgaatagcc tgttccttta accccaaatt     2340

tggctaaaat tggcctaaaa ctggcaaaca tttttccagt aacttttctt tttttcaaat     2400

gaattttctt catacttaaa aaagcccttt gctaaaatat aattttcaaa aaggtaaaat     2460

tatgtctatg gcactaatat aaaatgagta gaagttaatg attttactta actcattttt     2520

ttctttcttt cttttttttt tttttttttt gagacggagt cttgctctgt cacccaggct     2580

ggagtacagc agagcgatct cggctcactg caagctcctg caagctccgc ctcctggctt     2640

cacgccattc tccccctcag cctcccgagt agctgggact acag                      2684


<210>  882
<211>  6644
<212>  DNA
<213>  homo sapiens

<400>  882
attggagtgt ggagcaagcg gccggtctgc agtcggagac ttgcaggcag caaacacggt       60

gcgagcgaac aggagtgggg gggaaattaa aaaaagctaa acgtggagca gccgatcggg      120

gaccgagaag gggaatcgat gcaaggagca caataaaaca aaagctactt cggaacaaac      180

agcatttaaa aatccacgac tcaagataac tgaaacctaa aataaaacct gctcatgcac      240

catggttttt caaactcggt acccttcatg gattatttta tgctacatct ggctgctccg      300

ctttgcacac acaggggagg cgcaggctgc gaaggaagta ctactgctgg attctaaagc      360

acaacaaaca gagttggagt ggatttcctc tccacccaat gggtgggaag aaattagtgg      420

tttggatgag aactataccc cgatacgaac ataccaggtg tgccaagtca tggagcccaa      480

ccaaaacaac tggctgcgga ctaactggat ttccaaaggc aatgcacaaa ggatttttgt      540

agaattgaaa ttcaccctga gggattgtaa cagtcttcct ggagtactgg gaacttgcaa      600

ggaaacattt aatttgtact attatgaaac agactatgac actggcagga atataagaga      660

aaacctctat gtaaaaatag acaccattgc tgcagatgaa agttttaccc aaggtgacct      720

tggtgaaaga aagatgaagc ttaacactga ggtgagagag attggacctt tgtccaaaaa      780

gggattctat cttgcctttc aggatgtagg ggcttgcata gctttggttt ctgtcaaagt      840

gtactacaag aagtgctggt ccattattga gaacttagct atctttccag atacagtgac      900

tggttcagaa ttttcctctt tagtcgaggt tcgagggaca tgtgtcagca gtgcagagga      960

agaagcggaa aacgccccca ggatgcactg cagtgcagaa ggagaatggt tagtgcccat     1020

tggaaaatgt atctgcaaag caggctacca gcaaaaagga gacacttgtg aaccctgtgg     1080

ccgtgggttc tacaagtctt cctctcaaga tcttcagtgc tctcgttgtc caactcacag     1140

tttttctgat aaagaaggct cctccagatg tgaatgtgaa gatgggtatt acagggctcc     1200

atctgaccca ccatacgttg cgtgcacaag gcctccatct gcaccacaga acctcatttt     1260

caacatcaac caaaccacag taagtttgga atggagtcct cctgcagaca atgggggaag     1320

aaacgatgtg acctacagaa tattgtgtaa gcggtgcagt tgggagcagg gcgaatgtgt     1380

tccctgtggg agtaacattg gatacatgcc ccagcagact ggattagagg ataactatgt     1440

cactgtcatg gacctgctag cccacgctaa ttatactttt gaagttgaag ctgtaaatgg     1500

agtttctgac ttaagccgat cccagaggct ctttgctgct gtcagtatca ccactggtca     1560

agcagctccc tcgcaagtga gtggagtaat gaaggagaga gtactgcagc ggagtgtcga     1620

gctttcctgg caggaaccag agcatcccaa tggagtcatc acagaatatg aaatcaagta     1680

ttacgagaaa gatcaaaggg aacggaccta ctcaacagta aaaaccaagt ctacttcagc     1740

ctccattaat aatctgaaac caggaacagt gtatgttttc cagattcggg cttttactgc     1800

tgctggttat ggaaattaca gtcccagact tgatgttgct acactagagg aagctacagg     1860

taaaatgttt gaagctacag ctgtctccag tgaacagaat cctgttatta tcattgctgt     1920

ggttgctgta gctgggacca tcattttggt gttcatggtc tttggcttca tcattgggag     1980

aaggcactgt ggttatagca aagctgacca agaaggcgat gaagagcttt actttcattt     2040

taaatttcca ggcaccaaaa cctacattga ccctgaaacc tatgaggacc caaatagagc     2100

tgtccatcaa ttcgccaagg agctagatgc ctcctgtatt aaaattgagc gtgtgattgg     2160

tgcaggagaa ttcggtgaag tctgcagtgg ccgtttgaaa cttccaggga aaagagatgt     2220

tgcagtagcc ataaaaaccc tgaaagttgg ttacacagaa aaacaaagga gagacttttt     2280

gtgtgaagca agcatcatgg ggcagtttga ccacccgaat gttgtccatt tggaaggggt     2340

tgttacaaga gggaaaccag tcatgatagt aatagagttc atggaaaatg gagccctaga     2400

tgcatttctc aggaaacatg atgggcaatt tacagtcatt cagttagtag gaatgctgag     2460

aggaattgct gctggaatga gatatttggc tgatatggga tatgttcaca gggaccttgc     2520

agctcgcaat attcttgtca acagcaatct cgtttgtaaa gtgtcagatt ttggcctgtc     2580

ccgagttata gaggatgatc cagaagctgt ctatacaact actggtggaa aaattccagt     2640

aaggtggaca gcacccgaag ccatccagta ccggaaattc acatcagcca gtgatgtatg     2700

gagctatgga atagtcatgt gggaagttat gtcttatgga gaaagacctt attgggacat     2760

gtcaaatcaa gatgttataa aagcaataga agaaggttat cgtttaccag cacccatgga     2820

ctgcccagct ggccttcacc agctaatgtt ggattgttgg caaaaggagc gtgctgaaag     2880

gccaaaattt gaacagatag ttggaattct agacaaaatg attcgaaacc caaatagtct     2940

gaaaactccc ctgggaactt gtagtaggcc aataagccct cttctggatc aaaacactcc     3000

tgatttcact accttttgtt cagttggaga atggctacaa gctattaaga tggaaagata     3060

taaagataat ttcacggcag ctggctacaa ttcccttgaa tcagtagcca ggatgactat     3120

tgaggatgtg atgagtttag ggatcacact ggttggtcat caaaagaaaa tcatgagcag     3180

cattcagact atgagagcac aaatgctaca tttacatgga actggcattc aagtgtgata     3240

tgcatttctc ccttttaagg gagattacag actgcaagag aacagtactg gccttcagta     3300

tatgcataga atgctgctag aagacaagtg atgtcctggg tccttccaac agtgaagaga     3360

agatttaaga agcacctata gacttgaact cctaagtgcc accagaatat ataaaaaggg     3420

aatttaggat ccaccatcgg tggccaggaa aatagcagtg acaataaaca aagtactacc     3480

tgaaaaacat ccaaacacct tgagctctct aacctccttt ttgtcttata gactttttaa     3540

aatgtacata aagaatttaa gaaagaatat atttgtcaaa taaaatcatg atcttattgt     3600

taaaattaat gaaatatttt ccttaaatat gtgatttcag actattcctt tttaaaatca     3660

tttgtgttta ttcttcataa ggactttgtt ttagaaagct gtttatagct ttggaccttt     3720

ttagtgttaa atctgtaaca ttactacact gggtaccttt gaaagaatct caaatttcaa     3780

aagaaatagc atgattgaag atacatctct gttagaacat tggtatcctt tttgtgccat     3840

tttattctgt ttaatcagtg ctgttttgat attgtttgct aattggcagg tagtcaagaa     3900

aatgcaagtt gccaagagct ctgatatttt ttaaaaagaa tttttttgta aagatcagac     3960

aacacactat cttttcaatg aaaaaagcaa taatgatcca tacatactat aaggcacttt     4020

taacagattg tttatagagt gattttacta gaaagaattt aataaactcg aagtttaggt     4080

ttatgagtat ataaacaaat gaggcacttc atctgaagaa tgttggtgaa ggcaagtctc     4140

tgaaagcaga actatccagt gttatctaaa aattaatctg agcacatcaa gattttttca     4200

ttctcgtgac attaggaaat ttaggataaa tagttgacat atattttata tcctcttctg     4260

ttgaatgcag tccaaacatg aaaggaaata attgttttat attataactc tgaagcatga     4320

taaaggggca gttcacaatt ttcaccattt aaacacaaat ttgctgcaca gaatatcacc     4380

attgcagttc aaaacaaaac aaaacaaaaa gtcttttgtt tgtgaacact gatgcaagaa     4440

acttgttaaa tgaaaggact ctttacccta gaaggaagag gtgaaggatc tggcttgttt     4500

ttaaagcttt atttattaaa ccatattatt tgattactgt gttagaattt cataagcaat     4560

aattaaatgt gtctttatag atattgcagg aatgtataca tattgtgatt aatgctttca     4620

aaacttatga aaatcatgaa ctaccccaga attgaactgt tgtacttcca aagagaattg     4680

ggctgtttat aatgatttta atagagaaag atcccaggga tcggtcataa ttggtcttgt     4740

ttgataatgt gggcatccac aaacaaacaa acaaataaca gaaacaaaat ctgtaaatgt     4800

tcctttgtaa aacttgtaaa ttttatttat actgtcttgt tttgtacaca catttctctg     4860

tagtgggctc tgaatacatt gaaaatgcac tatatttttc tattttactt gcagagcatc     4920

acaaaagaac aggtattttc agtgctacat aatgtgtttt cccacattta ggaccaaaga     4980

cggctataga aaaactcaaa tggattgctt cccaaacccc tccccaccct ttttttttgg     5040

ttttaaatca ctgtacagtg ttatttgata ttttaattta ttttttgatt gactagaaaa     5100

atcattttaa tttcactaaa atgttttttg tccctaagga aaagtaatct gtaaaaataa     5160

ttttaattag cataatacag tcacctagac acttccattt gtaatctttg taatagactg     5220

taaatatatt tttggaacta taacacaatg tgcttgaggg ttatttttca gtgtctgcag     5280

tgtgtacaag tgtttatact aagtccagca ctttacaatt ctaatcagta gcattggcct     5340

ttgtgagaat gagtgaaaga gtttgagtga gtgttcttaa ttccttttgg attctagact     5400

cactaataat gaagttcttt tcttgttcat agcttaaggt gcttattttt tctattaaaa     5460

ttaaattaac aaaagccatt ctagaaatag aagacatagt atggtacatg caaacggtgt     5520

ctttcctgct tttttctagc actagattta tagttgagta gtctttcttg agtagaaggg     5580

cagaataaaa gtttttttga gtttttttca aaaataaatt tttccttcag caatatacct     5640

catctgcctt aaatttttta cagctcttta cagggaaagg ggagaaggga tgggaaagac     5700

acacagcaca ataggaagtg tatgattaca tcactatctc gtttgtaagt ttcttttcct     5760

aatcaacatt atgatttcga aatacatgta tgtgaaacaa atattaagag aaaaagaatt     5820

aacattgtaa tgctgattgt aatactctct tccagaaaga gatgagatgg tataacgata     5880

agaatgtaca acttgcacct tgaaatcttt ttttttaaat aaattagtgc tcaggggagg     5940

aaaagtagag aaagtgaacg tcaaaaatag aattccaaaa ttataaaaat gcaaaaggaa     6000

atggcctcct tgctttaata gagccacctt ttttagaaca ctgtcctcac acttgacctg     6060

tgttttgcat tcagtactga aataaaagta acttgttcta catttgaatc taacattttc     6120

tcagcaattg atctggtcct tgtttactag aactggtggt ttatgcttgt cagagcacta     6180

ttagttgaat catattgtat acttatgtaa tctacattag ctagtactgt ttaggactat     6240

attttaattg ctcttcttat ccgtgttttt aagacaatta aaatggtgtg attcacctct     6300

cttttttatt taggtaatgc tgatattctc ccttttgttt cttgagtagc ctagaactat     6360

gctactcact gatgtgcatg ttcaaataaa ttactgatgt gtattttttt gctatatgtg     6420

gagaaatcat ggggaactcg gggcgagatg tgcttttcgt tggttgaatt tgtccctcct     6480

tgcctaagaa atactacagg ggtcatcctt ttataaggac aaactgcttt tgaacagtgt     6540

cttcaatgta tcaagcacaa ataactcttt cttcaacatg aatcataagt ctctttttac     6600

cagcttaaaa taataaacaa gtctattaga caatgtaaag aaaa                      6644


<210>  883
<211>  4229
<212>  DNA
<213>  homo sapiens

<400>  883
tagagaacgt ggctcccgcg ggggcgctcg gagccgccgc acaggtagcg agagcgcggc       60

gccttctcct tcctttgtga gccgccgggc agggcaccga cctcgggttc tcccggcgcc      120

tccactgcag ggatctctag cctcgcacct cctcccctcg tcgcctgccc accctctgct      180

cctctcctgg cgccggggac cctgcccctt tgcgcctttt cctggctctg cctcggcttc      240

catttttctc tgcttccgaa aagccagtgg ggaagggcgg gggagacctg ccagtcctcc      300

cagacttctc ccgggttgct ccagctggcc ctcctcgccc cttcccggga gaggcacatg      360

gagagacatg aatcagggga gtggactgga cctgctgaag atctcatatg gaaaaggagc      420

cagaaggaaa aacagattta aaggatctga tggaagcacg tcatctgata ctacctcaaa      480

tagttttgtt cgccagggtt cggcagactc ctacactagc cgtccatccg attccgatgt      540

atctctggag gaggaccggg aggcagtgcg cagagaagcg gagcggcagg cccaggcaca      600

gttggaaaaa gcaaagacaa agcccgttgc atttgcggtt cggacaaatg tcagctacag      660

tgcggcccat gaagatgatg ttccagtgcc tggcatggcc atctcattcg aagcaaaaga      720

ttttctgcat gttaaggaaa aatttaacaa tgactggtgg atagggcgat tggtaaaaga      780

aggctgtgaa atcggattca ttccaagccc agtcaaacta gaaaacatga ggctgcagca      840

tgaacagaga gccaagcaag ggaaattcta ctccagtaaa tcaggaggaa attcatcatc      900

cagtttgggt gacatagtac ctagttccag aaaatcaaca cctccatcat ctggtgcaaa      960

atctgcagat gaacaagacc agtggaaaac tgcaggcttg ttttggcggt ttactacaga     1020

gcacactcct ccgtatgatg tggtaccttc catgcgacca gtggtcctag tgggcccttc     1080

tctgaagggc tacgaggtca cagatatgat gcaaaaagcg ctgtttgatt ttttaaaaca     1140

cagatttgaa gggcggatat ccatcacaag ggtcaccgct gacatctcgc ttgccaaacg     1200

ctcggtatta aacaatccca gtaagcacgc aataatagaa agatccaaca caaggtcaag     1260

cttagcggaa gttcagagtg aaatcgaaag gatttttgaa cttgcaagaa cattgcagtt     1320

ggtggtcctt gacgcggata caattaatca tccagctcaa ctcagtaaaa cctccttggc     1380

ccctattata gtatatgtaa agatttcttc tcctaaggtt ttacaaaggt taataaaatc     1440

tcgagggaaa tctcaagcta aacacctcaa cgtccagatg gtagcagctg ataaactggc     1500

tcagtgtcct ccagagctgt tcgatgtgat cttggatgag aaccagcttg aggatgcctg     1560

tgagcacctt gccgactatc tggaggccta ctggaaggcc acccatcctc ccagcagtag     1620

cctccccaac cctctcctta gccgtacatt agccacttca agtctgcctc ttagccccac     1680

cctagcctct aattcacagg gttctcaagg tgatcagagg actgatcgct ccgctcctat     1740

ccgttctgct tcccaagctg aagaagaacc tagtgtggaa ccagtcaaga aatcccagca     1800

ccgctcttcc tcctcagccc cacaccacaa ccatcgcagt gggacaagtc gcggcctctc     1860

caggcaagag acatttgact cggaaaccca ggagagtcga gactctgcct acgtagagcc     1920

aaaggaagat tattcccatg accacgtgga ccactatgcc tcacaccgtg accacaacca     1980

cagagacgag acccacggga gcagtgacca cagacacagg gagtcccggc accgttcccg     2040

ggacgtggat cgagagcagg accacaacga gtgcaacaag cagcgcagcc gtcataaatc     2100

caaggatcgc tactgtgaaa aggatggaga agtgatatca aaaaaacgga atgaggctgg     2160

ggagtggaac agggatgttt acatccgcca atgagttttg cccgtttgtg tttttttttt     2220

tttttttttg aagtcttgta taactaacag catccccaaa acaaagtctt tggggtctac     2280

actgcaatca tatgtgatct gtcttgtaat attttgtatt attgctgttg cttgaatagc     2340

aatagcatgg atagagtatt gagatacttt ttcttttgta agtgctacat aaattggcct     2400

ggtatggctg cagtcctccg gttgcatact ggactcttca aaaactgttt tgggtagctg     2460

ccacttgaac aaaatctgtt gccacccagg tgatgttagt gttttaagaa atgtagttga     2520

tgtatccaac aagccagaat cagcacagat aaaaagtgga atttcttgtt tctccagatt     2580

tttaatacgt taatacgcag gcatctgatt tgcatattca ttcatggacc actgtttctt     2640

gcttgtacct ctggctgact aaatttgggg acagattcag tcttgcctta cacaaagggg     2700

atcataaagt tagaatctat tttctatgta ctagtactgt gtactgtata gacagtttgt     2760

aaatgttatt tctgcaaaca aacaccttct tattatatat ataatatata tatatatcag     2820

tttgatcaca ctattttaga gtcttaatgc caagtcagca gatttgcttt atgaattaca     2880

gggactagaa atgcccacat tcaggaaatt tgtaataaca ttgtctagac acctatcctc     2940

attctagtag aaagtgtgta catactgtaa atatgtgtga ttgcttgact tgaaaaggtt     3000

tgaattctga atgttatacc atccttgtaa gtaagtttgt aatttccacc ataaattatg     3060

gtaaatataa aactccagag gttgttctac tccatacagt tcacactgat tgtgacacat     3120

tcttagtagc tagtgtctgt tctagtcact gcactggagt ctacgagccg gaactcgcta     3180

tatgcacgtg tgtgtgtccg tatgtaagaa agtgtgcacc gagtgactga atggttgaga     3240

tgaattggaa tgctgaagac taacgaagaa actagagact gatatcgagc attctgccca     3300

cctcgctctg tatttaatta attgtgctat atgttgcttt aacaacccat tgagcagtca     3360

gggaatgtga gtaagcttgc tgccaaaggt aactaggaaa gcattcatct gctgcctcct     3420

tgtttttgct cctagagagt gaaaatacag gcaattttac tgtgagtgtt tcactggaaa     3480

tgtacaatct ttgtgtgtta gagtatttgt tttagtaaga aatgtttaca cagcttgtgg     3540

aattatttcg tgggaaaata aatttttata acttctccca cttcaatttc taaccttgcc     3600

tattgttcct gttgtttgtt tacctcccag ttacctacca ttcctcccca ccaccgactc     3660

cagcaggttc actgtctgtc agaacccaga agtgcttctt ataaccaaag tttctgttct     3720

tcagaagaaa tcagggcaaa atggggtgac ttgaagtgaa taaaatgtta agaatattat     3780

cctacataag acatgtacac agaaggggaa ccttgaagac attatctcca tgcctcaatt     3840

acactgctgt aagaagctta caatgtcatc atgtttaagg ctaagacctt ttccgtgtct     3900

caagtgtata ttttgtccag ttataactgg atggtaagac agtattaaga gtgcaagtac     3960

ctggcacttg aagtttgtcc caggaaaatg cctgtgtata attacctaac ttcagatctg     4020

cacattaact tatttaacaa aataaatcag ccgggcgcag tggctcatgc ctgtaatccc     4080

agcaatttgg gaggctgagg agggtggatc acctgaggtc aggagttcaa gaccagcctg     4140

gccaacgtgg cgaaaccccg tctctactaa aaagataaaa aattagccag gtgtggtggt     4200

gcacacctgt aatcccagct acttgggag                                       4229


<210>  884
<211>  4324
<212>  DNA
<213>  homo sapiens

<400>  884
ggttgggctc gcggcgctgt gattggtctg cccggactcc gcctccagcg catgtcatta       60

gcatctcatt agctgtccgc tcgggctccg gaggcagcca acgccgccag tctgaggcag      120

gtgcccgaca tggcgagtgt agtgctgccg agcggatccc agtgtgcggc ggcagcggcg      180

gcggcggcgc ctcccgggct ccggctccgg cttctgctgt tgctcttctc cgccgcggca      240

ctgatcccca caggtgatgg gcagaatctg tttacgaaag acgtgacagt gatcgaggga      300

gaggttgcga ccatcagttg ccaagtcaat aagagtgacg actctgtgat tcagctactg      360

aatcccaaca ggcagaccat ttatttcagg gacttcaggc ctttgaagga cagcaggttt      420

cagttgctga atttttctag cagtgaactc aaagtatcat tgacaaacgt ctcaatttct      480

gatgaaggaa gatacttttg ccagctctat accgatcccc cacaggaaag ttacaccacc      540

atcacagtcc tggtcccacc acgtaatctg atgatcgata tccagaaaga cactgcggtg      600

gaaggtgagg agattgaagt caactgcact gctatggcca gcaagccagc cacgactatc      660

aggtggttca aagggaacac agagctaaaa ggcaaatcgg aggtggaaga gtggtcagac      720

atgtacactg tgaccagtca gctgatgctg aaggtgcaca aggaggacga tggggtccca      780

gtgatctgcc aggtggagca ccctgcggtc actggaaacc tgcagaccca gcggtatcta      840

gaagtacagt ataagcctca agtgcacatt cagatgactt atcctctaca aggcttaacc      900

cgggaagggg acgcgcttga gttaacatgt gaagccatcg ggaagcccca gcctgtgatg      960

gtaacttggg tgagagtcga tgatgaaatg cctcaacacg ccgtactgtc tgggcccaac     1020

ctgttcatca ataacctaaa caaaacagat aatggtacat accgctgtga agcttcaaac     1080

atagtgggga aagctcactc ggattatatg ctgtatgtat acgatccccc cacaactatc     1140

cctcctccca caacaaccac caccaccacc accaccacca ccaccaccat ccttaccatc     1200

atcacagatt cccgagcagg tgaagaaggc tcgatcaggg cagtggatca tgccgtgatc     1260

ggtggcgtcg tggcggtggt ggtgttcgcc atgctgtgct tgctcatcat tctggggcgc     1320

tattttgcca gacataaagg tacatacttc actcatgaag ccaaaggagc cgatgacgca     1380

gcagacgcag acacagctat aatcaatgca gaaggaggac agaacaactc cgaagaaaag     1440

aaagagtact tcatctagat cagccttttt gtttcaatga ggtgtccaac tggccctatt     1500

tagatgataa agagacagtg atattggaac ttgcgagaaa ttcgtgtgtt tttttatgaa     1560

tgggtggaaa ggtgtgagac tgggaaggct tgggatttgc tgtgtaaaaa aaaaaaaaat     1620

gttctttgga aagtacactc tgctgtttga cacctctttt ttcgtttgtt tgtttgttta     1680

atttttattt cttcctacca agtcaaactt ggatacttgg atttagtttc agtagattgc     1740

agaaaattct gtgccttgtt ttttgtttgt ttgttgcgtt cctttctttt ccccctttgt     1800

gcacatttat ttcctccctc taccccaatt tcggattttt tccaaaatct cccattttgg     1860

aatttgcctg ctgggattcc ttagactctt ttccttccct tttctgttct agttttttac     1920

ttttgtttat ttttatggta actgctttct gttccaaatt cagtttcata aaaggagaac     1980

cagcacagct tagatttcat agttcagaat ttagtgtatc cataatgcat tcttctctgt     2040

tgtcgtaaag atttgggtga acaaacaatg aaaactcttt gctgctgccc atgtttcaaa     2100

tacttagagc agtgaagact agaaaattag actgtgattc agaaaatgtt ctgtttgctg     2160

tggaactaca ttactgtaca gggttatctg caagtgaggt gtgtcacaat gagattgaat     2220

ttcactgtct ttaattctgt atctgtagac ggctcagtat agatacccta cgctgtccag     2280

aaaggtttgg ggcagaaagg actcctcctt tttccatgcc ctaaacagac ctgacaggtg     2340

aggtctgttc cttttatata agtggacaaa ttttgagttg ccacaggagg ggaagtaggg     2400

aggggggaaa tacagttctg ctctggttgt ttctgttcca aatgattcca tccacctttc     2460

ccaatcggcc ttacttctca ctaatttgta ggaaaaagca agttcgtctg ttgtgcgaat     2520

gactgaatgg gacagagttg attttttttt ttttttcctt tgtgcttagt taggaaggca     2580

gtaggatgtg gcctgcatgt actgtatatt acagatattt gtcatgctgg gatttccaac     2640

tcgaatctgt gtgaaacttt cattccttca gatttggctt gacaaaggca ggaggtacaa     2700

aagaagggct ggtattgttc tcacactggt ctgctgtcgc tctcagttct cgataggtca     2760

gagcagaggt ggaaaaacag catgtacgga ttttcagtta cttaatcaaa actcaaatgt     2820

gagtgttttt atctttttac ctttcataca ctagccttgg cctctttcct cagccttaag     2880

aaccatctgc caaaaattac tgatcctcgc atgatggcag ccatagtgca tagctactaa     2940

aatcagtgac cttgaacata tcttagatgg ggagcctcgg gaaaaggtag aggagtcacg     3000

ttaccattta catgttttaa agaaagaagt gtggggattt tcactgaaac gtctaggaaa     3060

tctagaagta gtcctgaagg acagaaacta aactcttacc atatgtttgg taagactcca     3120

gactccagct aacagtccct atggaaagat ggcatcaaaa aagatagatc tatatatata     3180

tataaatata tattctatta cattttcagt gagtaatttt ggattttgca aggtgcattt     3240

ttactattgt tacattatgt ggaaaactta tgctgattta tttaaggggg aaaaagtgtc     3300

aactctttgt tatttgaaaa catgtttatt tttcttgtct ttattttaac ctttgataga     3360

accattgcaa tatgggggcc ttttgggaac ggactggtat gtaaaagaaa atccattatc     3420

gagcagcatt ttatttaccc ctcccctatc cctaggcact taaccaagac aaaaagccac     3480

aatgaacatc cctttttcaa tgaattttat aatctgcagc tctattccga gcccttagca     3540

cccattccga ccatagtata atcatatcaa agggtgagaa tcatttagca tgttgttgaa     3600

aggttttttt tcagttgttc tttttagaaa aaaagaaaaa caaaaacaaa aacaaaaaaa     3660

aaaaatcaca ccattgctca cagaattggc atctcatttt tgggacctcc catctttctg     3720

ttttgaaaag tgtacagtag tgcagtgttc ctgatgtaac tttatggctt acaatgttga     3780

catgtctcag gttcatgtgt tgcgattggt gttttccgtc tcaggtagat tgcaaagtgt     3840

aggccccaca cattggaaaa aataataata aaacaaagca aaaacaggaa attatggatt     3900

ttagttgtat attggtttat gtattttttc ttaagtatac agtgcactgt ttgaaatgta     3960

ttgttgagta ttactttgta caggttgatc acttttttta gagtgaagaa agaacaaact     4020

tgttttttgt gttttttaaa ggaatataaa ataatgaagg atgtataatt gatgccaaat     4080

aagcttgttc tttagtcaca ccgacgtctt atttttccct ttaggccagt tctgttttta     4140

aggtgtacat ggacaatgtt acagtgtaag aaactccata tccatatgtt cccattcgca     4200

ttttgtattg gttcatgtat accattttta caaaaaaaaa aagaaaaaaa agaagtacta     4260

taaaatatct gtcttcttaa taaaaaaaaa ttaatgttac aaagtgaaaa aaaaaaaaaa     4320

aaaa                                                                  4324


<210>  885
<211>  2794
<212>  DNA
<213>  homo sapiens

<400>  885
tgattgaggt gcagagcaaa gtgaagggct gcccaggtga ggccaggctg actgaaaaag       60

atggatacta ctatgctgaa tatgcggaat ctgtttgagc agcttgtgcg cggggcggag      120

attctcaagg aaggaaacga actccaattt atccagttgg tgaaggactt tgaggatttc      180

tttaaaaagt gggagaggac tgactatgag ctggggaaat acaaggatct tttgataaaa      240

gcagagactg agtgaagtgc tctggatgtt aagctgaagc atgcacataa tcaggtggat      300

gcagacatcc aaacggagag ctgaggctaa ctgcgaaaag ctggagtaac agattcagct      360

gattggagag atgttcctgt gtgacatatc tggcagcatt caactaagcg gggagcaaaa      420

atcagctttg gcttttctca acagaggcca accatccagc agcaatgctg ggaacaaaag      480

actttaaatt agcgatgaat ctggttccat tttatcaggt atcagctttg acaagactga      540

tgaatcactg gattgcgact cttctttggt gaagactttc aagcggaagc agagagaaaa      600

gaggtgctct agtagccgac agtttgttga tggtccctct ggacctgtaa aggaaactcg      660

ttccattggc tccacagtag accaggggga atgaatccat agttgcaaaa actacagtga      720

ctgttcccaa ggatggcggg cccatcaaag ctgtgcccac tattgagact gtgccatact      780

ggaccaggag ccaaaggaaa acaggtactt tacaaccttg gaacagtgac cccaccctga      840

acagcaggca gctggagcca agaactgaga caatgtgggc acgccacaga gtaacagagg      900

gatgtgcctg aatgactttg tctctaagac ggttattaaa cctgaattct atgttccatg      960

tggaaagcag ataaaatttg ggaaactatc tctgaagtgt caggactgtt gtgtgatctc     1020

tcgtccagaa tgtcgggacc actgtcccct tccctgcatt cctaccctga taggaacacc     1080

tgtcaagatt ggagagggaa tgctggccga ctttgtgtcc cagacttttc caatgatccc     1140

ccgcattgtt gtgcattgtg taaatgagat tgagcagaga ggtcttactg agacaggcct     1200

gtataggatc ttgggctgtg acagcacagt aaaagctgaa agagaaattc ctcagagtga     1260

aaactgtacc cctcgtcagc aaagtggatg atatccatgc tatctgtagc cttcttaaag     1320

actttcttcg aaacttcaaa gaacctcttc tgacctttcg cctaaacaaa gcctttatgg     1380

aagcagcaga aatcacagat gaagacaaca gcatatctgc catgtaccag gctgttggtg     1440

aactgcccca ggccaacagg gacacattgg ttttcctcat gattcacttg cagagagtgg     1500

ctcagagtcc atatactaaa atgaatgttg ccaatctggc tgaagtcttt ggctctacaa     1560

tagtggccca tgctgtgccc aatccagaac cagtgacgat gttacaggac atcaagtgtc     1620

aacccaaggt ggtcgagcgc ctgccttcct tgcccctgga gtactggagt cagttctcaa     1680

tagtggagca gagaacattg accccctaca tgtcactgaa aactcaaatg ccttttcaac     1740

accagatatt aaagtgagtt tactgggacc tgtgaccact cctgatcatc agcttctcaa     1800

gactccttca tctagttccc tgtcacaggg agtctgttcc accctcacaa agaacactcc     1860

cagatttggg agcaaaggca agtctgccac taacctagga aggcaaggca acctttttgc     1920

ttcttcaatg ctcaagtgaa gtcacatcta cctattactc ccagcattga ttgactataa     1980

gaaaggatgc acctgtactc tctgctctac agcctcctct tctcattact atttttagca     2040

ttctccaggc ttttactcaa gtttaatttt gcatgagggt tttactaaaa ttttatatat     2100

ctccccttcc ttctcctcga gtcacataat atcagtacct tgttctggtc actgttggga     2160

gcttttagat gagacatctt tccaggagta gaagggttag tatggaattg attgtgattc     2220

ttttggggga agggggttac tatccctttg gcttaaagcc aaatgctgct catggaatga     2280

acgatctttc tctagtttca ttcaactgat ttccatgaga caatgacaga aaccctacct     2340

atctgataag attggcttgt ctcagggtgg gaagtgggag ggtggggcga agaaaggatt     2400

acaccagaag atttaggatg cctccttcta agaactggaa gttctcattc cccattatga     2460

actgagctat aatatggagc tttcataaaa atgggatgca ttgaggacag aactagtgat     2520

gggagtatgt gtagctttga tttggatgat taggtcttta atagtgttga gtggcacaac     2580

cttgtaaatg tgaaagtaca acgcatattt atctctgatg tgccattggc tgaaccttgg     2640

gttaatttgg ggtcaaagtc agtttttctt ttaaaattga attcattctg atgcttgacc     2700

cccatactcc caaccttgtc cagtggagcc caacttccaa aggtcaatat gtcgtccttt     2760

ggcatcccaa ctaacaataa agaataggct ataa                                 2794


<210>  886
<211>  3907
<212>  DNA
<213>  homo sapiens

<400>  886
gaacaaatca aatcgaagca aagaaactgc cggctttcaa aatcctcctc ctccgccatc       60

atccgccgcg gtgcggagag caggtggtgc tggaagcgcg tgaggccggg agctcgagag      120

agctaacaga ctagccggct ggacatctgg accgctggat ccggaggtgg cgaccccggc      180

ctgacccgga ccctaaatcc gtccccgccc cagagggcgg aggcgcgcgc tcgattcccc      240

ccacgcggcg gcgccgcctg tttacgtctg cagatctcca ggggagccca ccagcctagt      300

caacatggcc tcggaagaca ttgccaagct ggcagagaca cttgccaaga ctcaggtggc      360

cgggggacag ctgagtttca aaggcaagag cctcaaactc aacactgcag aagatgctaa      420

agatgtgatt aaagagattg aagactttga cagcttggag gctctgcgtc tggaaggcaa      480

cacagtgggc gtggaagcag ccagggtcat cgccaaggcc ttagagaaga agtcggagtt      540

gaagcgctgc cactggagtg acatgttcac gggaaggctg cggaccgaga tcccaccagc      600

cctgatctca ctaggggaag gactcatcac agctggggct cagctggtgg agctggactt      660

aagcgacaac gcattcgggc ccgacggtgt gcaaggcttc gaggccctgc tcaagagctc      720

agcctgcttc accctgcagg aactcaagct caacaactgt ggcatgggca ttggcggcgg      780

caagatcctg gctgcagctc tgaccgaatg tcaccggaaa tccagtgccc aaggcaagcc      840

tctggccctg aaggtctttg tggctggcag aaaccgtctg gagaatgatg gcgccactgc      900

cttggcagaa gcttttaggg tcatcgggac cctggaggag gtccacatgc cacagaatgg      960

gatcaaccac cctggcatca ctgccctggc ccaggctttc gctgtcaacc ccctgctgcg     1020

ggtcatcaac ctgaatgaca acaccttcac tgagaagggc gccgtggcca tggccgagac     1080

cttgaagacc ttgcggcagg tggaggtgat taattttggg gactgcctgg tgcgctccaa     1140

gggtgcagtt gccattgcag atgccatccg cggcggcctg cccaagctaa aggagctgaa     1200

cttgtcattc tgtgaaatca agagggatgc tgccctggct gttgctgagg ccatggcaga     1260

caaagctgag ctggagaagc tggacctgaa tggcaacacc ctgggagaag aaggctgtga     1320

acagcttcag gaggtgctgg agggcttcaa catggccaag gtgctggcgt ccctcagtga     1380

tgacgaggac gaggaggagg aggaggaagg agaagaggaa gaagaggaag cagaagaaga     1440

ggaggaggaa gatgaggaag aggaggaaga agaggaggag gaggaggaag aagagcctca     1500

gcagcgaggg cagggagaga agtcagccac gccctcacgg aagattctgg accctaacac     1560

tggggagcca gctcccgtgc tgtcctcccc acctcctgca gacgtctcca ccttcctggc     1620

ttttccctct ccagagaagc tgctgcgcct agggcccaag agctccgtgc tgatagccca     1680

gcagactgac acgtctgacc ccgagaaggt ggtctctgcc ttcctaaagg tgtcatctgt     1740

gttcaaggac gaagctactg tgaggatggc agtgcaggat gcagtagatg ccctgatgca     1800

gaaggctttc aactcctcgt ccttcaactc caacaccttc ctcaccaggc tgctcgtgca     1860

catgggtctg ctcaagagtg aagacaaggt caaggccatt gccaacctgt acggccccct     1920

gatggcgctg aaccacatgg tgcagcagga ctatttcccc aaggcccttg cacccctgct     1980

gctggcgttc gtgaccaagc ccaacagcgc cctggaatcc tgctccttcg cccgccacag     2040

tctgctgcag acgctgtaca aggtctagac tcaaagcctc tcccatccct tggcctggac     2100

cagtgagctg gggagggact cggatgaact gaggcgcagc ctacgccatt gccttggaca     2160

ggactctggc cacaggcagg gcgggtctgt gtcccatgtg tcctgtcagt cccctgagta     2220

tgtgtgtggg tgtggcgcat gtgcaggtct gtgcctcctg tcgggatttg ggttttaacg     2280

tcttctgctg gcccagccct gctctgttgt ggggagttgg cccccagggg aaagggctgt     2340

gagctgctcc gccattaaac tcacctccac ctgagggcgc tctgctgatc tccgcctggg     2400

ccctgatggc cgtccccacc cacctgcctt ccggcccggc tccctggcgg agccagaacc     2460

cagggagttg cccgcgtgct gtccttcccc tctgtgttgt gattgggttg tttcctgccc     2520

tgcctggggc tgcttctcgt caccaagccc tggtcctgcg gcagctgtca cccctaccat     2580

ccataccact gtgctgaccg ctcagcctga agagcagaga atgccatggg tgggactgtg     2640

ggggtcggat cgtggggttg ttggcagagg gcaaccctgg gccccacacc gtgtggacag     2700

gcagacacca gattgtccag gagcaggagc tgctgggact gcgctggccc cggacctagt     2760

gggccttctc ctggctgctg agatgtcgtc tgtgactggc ctggctggag ggggagtgtt     2820

gacaacccaa agctgttctc cagtctgggg agggagaggc agggtcccca atgtccgagc     2880

tgcatctgga cgctgctctt aaaggacctc ctggggcagg ggagcggtag ggtctggact     2940

gggcagatgc tgtatgacct ccctgagcac ccgtgactgc cccatgcttt cccctttgtg     3000

ctctgtgtgt gtctgggctg tgcccggggg cttcacaaat aaagtcgtgt ggcagcttca     3060

gagactcaga aactctcact gaaagcggga tagtctcggg ggccgttgta cgtggagtcc     3120

cacctcggca gagcatgcgg ccccgcagca gtctgtgggg cagtcagccc tgcagaaggg     3180

cccggcctcg gcctcaggcc actacctggg aagtggcagt cctgagtggg ggcccatttt     3240

cctgcctggc cacacctcac ccagcaccct gcctttgggc tgcagctcgc ttggcttctg     3300

cgttgctcct tcactatgga agccacctcc cttgggatcc tttgctccac tgccacatat     3360

gtgaggacag cccagccaac cttccttacc tcctacccta caccatgtat gtgctttggg     3420

agcccatgtc ccccacaaac ggcctccaag aagtccctcc aaggtttctt agagggcaat     3480

attttctcat tggcagtcgg ccacgtaggt gaccaggtgg cagaggatac tgctggccct     3540

gtcccctgtc ttctgtgtga gttgatacgg tagggggtgg gtgtggggct ggcattaagt     3600

tctgatgcca gctacaacgt ggatgaactt tgaaaacatg ttaaatgaaa taagccagac     3660

acaaaaggac aaatatgatt ccatttagat gaggcatcta gaataagcaa attcagagac     3720

aagaaggtag aggttgccag ggctagggga agggtggaat agggagtgag gctgcaaaca     3780

gattctctgg gatgatgaag atgttctgga aatggagagt ggtgatggtt gcataacatt     3840

gtgaatgtac ttaatgcact gaattgtaca cataaaaatg gttaaaatga tagaaaaaaa     3900

aaaaaaa                                                               3907


<210>  887
<211>  3684
<212>  DNA
<213>  homo sapiens

<400>  887
agcgggacag acgagcggga ggggcagcgt gcggggagct gggggcgggg cgcggccgca       60

gctccgtttc cggtggctcg tcgcgctcgc tcactccagc tgcagccact ctcgcccgtg      120

gctgcttcct ccatcctggt attttttgga gcttccatcc tggttcttcc aaagtgcccg      180

gacccaaaac aggaaagtgt tgcggagata ggaacatggg agagaaacaa tctgggtaac      240

atgaaagtga tgctggttgc taagggaagg caacttgatt ctgtgggaag ggctgtagct      300

gatccatccg ttgtctagaa gcggatgaaa tagactcaga agatagtatt gaacctccac      360

ataaaaggct ttgtttgtcc tctgaggatg atcagagtat tgatgattct actccttgca      420

tatcagttgt tgcacttcca ctttcagaaa atgatcagag ctttgaagtg accatgactg      480

caaccacaga agtagcagat gatgaggtta ctgaggggac tgtgacacag atacagattt      540

tgcagaatga gcaactagat gaaatatctc ccttgggtaa cgaggaagtt tcagcagtta      600

gccaagcatg gtttacaact aaagaagata aggattctct gactaataaa ggacataaat      660

ggaagcaggg gatgtggtcc aaggaagaaa ttgatatttt gatgaacaat attgaacgct      720

atcttaaggc acgcggaata aaagatgcta cagaaatcat ctttgagatg tcaaaagacg      780

aaagaaaaga tttctacagg actatagcat ggggtctgaa ccggcctttg tttgcagttt      840

atagaagagt gcttcgcatg tatgatgaca gaaaccatgt gggaaaatat acacctgaag      900

aaattgagaa gctcaaggag ctccggataa agcatggcaa tgactgggca acaatagggg      960

cggcgctagg aagaagtgca tcttctgtca aagatcggtg ccgactgatg aaggatactt     1020

gcaacacagg gaagtggaca gaagaagaag aaaagagact tgcagaagtg gttcatgagt     1080

tgacaagcac tgagccaggt gacatagtca cacagggtgt gtcttgggca gctgtggctg     1140

aacgagtcgg tacccgctca gaaaagcaat gtcgttctaa atggctcaac tacctgaatt     1200

ggaaacagag tgggggtact gaatggacca aggaagatga aatcaatctc atcctcagga     1260

tagcagaact tgatgtagct gatgaaaatg acattaactg ggatctgtta gctgagggat     1320

ggagtagtgt ccgttcacca caatggctac gaagtaaatg gtggaccatc aaaaggcaaa     1380

ttgcaaacca taaggatgtt tcgttccctg tcttaataaa aggtcttaaa cagttacatg     1440

agaaccaaaa aaacaaccca acgcttttgg agaataaatc aggatctgga gttccaaaca     1500

gtaataccaa ttccagtgtg cagcatgttc agataagagt tgcccgcttg gaagataata     1560

cagccatctc ttctagcccc atggcagcat tgcagattcc agtccagatc acccatgttt     1620

cttcagcaga ctctcctgct accgttgact cagaaacaat aacactaaac agtggaacac     1680

tacagacatt tgagattctt ccctctttcc atctacagcc cactggcact ccaggcacct     1740

acctacttca aacaagctca agccaaggcc ttcccctaac tctgactgct agtcccacag     1800

taaccctgac agctgctgct cctgcttctc ctgaacagat tattgttcat gctttatccc     1860

cagaacattt gttgaacaca agtgataatg ttacagtgca gtgtcacaca ccaagagtca     1920

tcattcagac tgttgccaca gaggacatca cttcttccat atcccaagca gaactgacag     1980

tcgatagtga tattcagtca tctgattttc ctgagcctcc agacgcccta gaagcagaca     2040

ctttcccaga tgaaattcat caccctaaga tgactgtgga gccatcattt aatgatgctc     2100

atgtatccaa attcagtgac caaaatagca cagaactgat gaatagtgtt atggtcagaa     2160

cagaagaaga aatctctgac accgacctta aacaagagga atcaccctct gatttagcca     2220

gtgcttatgt tactgagggt ttagagtctc ccactataga agaacaagtt gatcaaacaa     2280

ttgatgatga aacaatactt atcgttcctt caccacatgg ctttatccag gcatctgatg     2340

ttatagatac tgaatctgtc ttgcctttga caacactaac agatcccata ctccaacatc     2400

atcaggaaga atcaaatatc attggatcat ccttgggcag tcctgtttca gaagattcaa     2460

aggatgtcga agatttggta aactgtcatt agaataattc ttagaaatag gcagttcaag     2520

caaagaaggc acactgttaa ttacaacctc ttcaaagaaa taggagcaac ccccaagagg     2580

cttaatttac caatttaaat agccacagtc cttaagccac acacattgtt gctgctatga     2640

ctttttacct cctttaaaca catcatctga ggttgagttt tatgacagta tgtagttgag     2700

tggaggctgg gagttttaag cataaatccc tgtttagtgt tacatgggaa taaggaattt     2760

cattcacttc agccactaag aaaagtttag aatcacgaaa gcttaactgc tgtggtttaa     2820

agtacagttt ctctaaagat cagacatggc actgtctcct ctcaagcctg gttgtagttc     2880

agatgagtct tttcaacatg gtcttcaaca tggtctagag cttaccagtg atcttctgat     2940

cttcaagaag actaagtttg agacttgacc agcatacaag tatagagacc taggaggtgg     3000

tcttgtggtg gtacatttgg ttaacccatt gctggcagtg ggagctgatt taggcagggt     3060

aaacaggaaa gcattaaaag ttaaaattca ctacaggttt tttgttactt ttaaagggaa     3120

tatggataag catagtaaca aaacccacca gaatctaagc agttttcacc ccctcagaaa     3180

ccactgtcat tagtttacaa agttagcact ttgaagtaaa actaaatgag gaaggaagta     3240

atgttaccta tccttgatac catgaccatt tattagatgt tttgctatat aaattaccga     3300

gagaatagtt tgtcatccac ttagtgtgtt agctggtggg gtacaatata acctctcatc     3360

tcaggctatt ttaaaaaaac aatatttgct tctataacaa aaggaaacaa atctaagaat     3420

cattcctgta ctacagaagg gttaaggcaa aggtagcctt ttgggctttt taatgaatat     3480

gacccctata gaaaagtcaa gaaaaaaaaa cccttgtata aattatttta tttattattg     3540

taattagatc ttcacaaagt tgtcttttca ctgtgttttg tcaacgtgaa attaaattgt     3600

agttataagc aaaagttggt tgcctaggga acaattgtat attcagttta acagaaataa     3660

aagaatattt gtcttaagat gcaa                                            3684


<210>  888
<211>  2911
<212>  DNA
<213>  homo sapiens

<400>  888
gcggccgcct ccccctcccc ctccccctct ttcttctcct ccctcgtcgc cgccgccgcc       60

gccgccgcct cagccttcgc ctcagccgcc gcccgctccc gcccgcgcgc ggcgggatgg      120

acgatcaatc caggatgctg cagactctgg ccggggtgaa cctggctggc cactcggtgc      180

aggggggcat ggccctgccg cctcccccgc acggccacga aggggcggac ggcgacggca      240

ggaagcagga catcggcgac atcctccacc agatcatgac catcaccgac cagagcttgg      300

acgaggcgca agcaaagaaa catgccctga actgtcacag aatgaaacca gcgctcttca      360

gcgtcctgtg tgagatcaaa gagaaaacag gtctcagcat cagaggagcc caggaggagg      420

accctcccga tccccagcta atgagactgg acaatatgct tttggcagaa ggggtttcag      480

gtcctgagaa aggtggggga tcggcggcag cagctgcagc cgcggcagcc tctggaggtt      540

cttcagataa ctctattgaa cactcagatt acagagccaa attgacccag atcagacaaa      600

tctatcacac agaactggag aaatatgaac aggcatgtaa tgaatttact acacatgtga      660

tgaaccttct ccgagaacag agtagaacac gtcccatttc tccaaaagag attgaaagaa      720

tggtgggcat catccatcga aaatttagtt ccattcagat gcagctcaaa caaagcactt      780

gtgaagcagt tatgatttta agatcaaggt tccttgatgc cagacggaaa aggcgtaact      840

tcagtaaaca ggccacagaa atcttgaatg aatattttta ctcacacctc agcaacccct      900

accccagtga agaagccaaa gaggagctgg ccaagaaatg cagcatcaca gtgtcacagg      960

tatccaattg gtttggcaac aaacgaatca ggtacaagaa gaacattggc aagtttcagg     1020

aagaagccaa cctctatgct gcaaagacgg ccgtgacagc tgcacacgca gtagcagcag     1080

ctgtgcagaa caaccagacc aattcgccca ccacaccaaa ttccggttct tctggttctt     1140

ttaacctccc aaattctggg gacatgttca tgaacatgca gagtctgaat ggggattctt     1200

accaagggtc ccaagtcgga gccaatgtgc aatcacaggt ggataccctc cgtcatgtta     1260

tcaatcagac gggaggctac agtgatggcc ttggaggaaa ttcactgtac agtccacata     1320

atttaaatgc taatggaggc tggcaggacg caacaactcc atcttctgtg acttctccta     1380

cagaaggccc aggaagtgtg cactcggata cctctaacta atctctggcc acacttttcc     1440

ctgagctaca tgccttgata agtgcattca gagcaatagg aggaaaagga aagcgttttt     1500

gtagcccacc atctacagct ttactgtaaa accttgtctt attcgagaac ttggtaaatc     1560

tgttttttaa ggaatcataa tcatttgtat ttatacttaa aaacacacaa tgttaaaaaa     1620

aataaagcac tttatccaat taggccaaga tttaacattg ttgacagtcc tgtagctatt     1680

ttatcataat ttattatcaa tattttacat taatggtttc acagttgcca attacttggc     1740

cttaagggta aaaagtacaa tatacactaa acctcaaccg ttaaagcaga tgcaaaaatt     1800

cacctcacct aaattgaact tcttgcatat ttccattact gacttggatt gtctttcttt     1860

catatcacta atggagttgg aataaagagc tgtttgccta tccctgttaa tgatggttgt     1920

gtttaagaat cttcctcgtc acgtttgtgt tcagatctct tatgttataa ttagatcaga     1980

gactggtagc atcgtttctc tctctgaaag caccagtgcc cagagtctgc tcggtaataa     2040

aattatggat ccagattgtt ctgagagacg aagatacttg ctgctgatag aggtgaaaac     2100

gagattgatc cgtctggggt tttacggtgt gcactgggtg ctgcacagac ttgtcaaggt     2160

ttgctacgtc ctctgggcat ctgcaaaagg ccctgctctc tggagtgttg tatatagtgt     2220

agcaaaagag tatttataca tcccaccaat caaaacacag ctttattacc tcatgcgaac     2280

tcatacaaac caatagaatt tcaacatgtt ctgtagctta gagtgctcac ttactacctc     2340

tgaacaatac tcacgctgta gtttgtctct ttcttatctt tttgcatctt gtaattaact     2400

ctttgtttcc cttcataaaa tgtaatgtac attgtaatct tttaaaagaa aaatcagggt     2460

tgcacttgca acttttaaaa aaccgagtgt ggaaacattg ggtcttaatt caacacagga     2520

tcggtaaaac tgttgtaaat actgagaaac attttgaatg ttcttcatct tattactaat     2580

ccatgcaaaa aaaaaaaaaa aagcagcgac taattgtgat gcattcagat ttcagtattc     2640

agtactgtat atttcaccct gtgtaatggg gccccctctc ctttctctct ttttgtattg     2700

tatgcgattc tgaaactgat tgagtcatga aaataatttg tggcggtgat tctaatgtat     2760

taaaaacgtt tcgtgttcct ttctaactgg attacaccct ggattgaaaa agtcttcctc     2820

gtggtagtta tatgtagttt caaacatgaa taaacttttt gctttcatga ttaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                                    2911


<210>  889
<211>  2580
<212>  DNA
<213>  homo sapiens

<400>  889
ataaggtatg aaagatgtgg cctgcagaga gccggcacta tctctactgc tgctgctgct       60

gctactgctg ctgttgctac cgctgcctct gctgccaccg ccactactgc tgccagcgga      120

gccgctagga gtgagcatcc cctctccggg atacccagct ccgcggcgtc tcccgcgcgc      180

cctggcccca cacggacctg ccagccccag ggaacaaaag cggagcccgc tcgccctcta      240

ctgcagccgg aggatgagtc gagagggctg agcggagagt gtggtcctcg gcggctggag      300

ctatttcctt ggcttctctc catgacgatt cctgactcgt ggccccggca atcttgggaa      360

gacatcatcc agcttcttca gtccagaccc tgggcacccc ccttttgcca ggatcgtccc      420

cacccagcct ggacacattg actgaactgt tttctaggac actgcactca gcaagacatg      480

gtggtgagcc ctgactctca gtcttcatga ttgaagaact cttttgtaca acacaaagca      540

ctcaaaaaga gtgaatgaaa tgtgcagctc agagtgtcat ttctgaaggg aggagtcttt      600

ctcttggaga agagtcctca atgagcctgg ccgaggcccg ggatctgtgt gaagtggact      660

aaggattaag taggatgtca actgagacag aacttcaagt agctgtgaaa accagcgcca      720

agaaagactc cagaaagaaa ggtcaggatc gcagtgaagc cactttgata aagaggttta      780

aaggtgaagg ggtccggtac aaagccaaat tgatcgggat tgatgaagtt tccgcagctc      840

ggggagacaa gttatgtcaa gattccatga tgaaactcaa gggcgttgtt gctggcgctc      900

gttccaaagg agaacacaaa cagaaaatct ttttaaccat ctcctttgga ggaatcaaaa      960

tctttgatga gaagacaggg gcccttcagc atcatcatgc tgttcatgaa atatcctaca     1020

ttgcaaagga cattacagat caccgggcct ttggatatgt ttgtgggaag gaagggaatc     1080

acagatttgt ggccataaaa acagcccagg cggctgaacc tgttattctg gacttgagag     1140

atctctttca actcatttat gaattgaagc aaagagaaga attagaaaaa aaggcacaaa     1200

aggataagca gtgtgaacaa gctgtgtacc agacaatatt ggaagaggat gttgaagatc     1260

ctgtgtacca gtacattgtg tttgaggctg gacacgagcc aatccgtgat cccgaaacgg     1320

aagaaaacat ttatcaggtt cccaccagcc aaaagaagga aggtgtttat gatgtgccaa     1380

aaagtcaacc tgtaagtgct gtgacccaat tagaactttt tggggacatg tccacacccc     1440

ctgatataac ctctcccccc actcctgcaa ctccaggtga tgcctttatc ccatcttcat     1500

ctcagaccct tccagcgagt gcagatgtgt ttagttctgt acctttcggc actgctgctg     1560

taccctcagg ttacgttgca atgggcgctg tcctcccgtc cttctggggt cagcagcccc     1620

tcgtccaaca gcagatggtc atgggtgccc agccaccagt cgctcaggtg atgccggggg     1680

ctcagcccat cgcatggggc cagccgggtc tctttcctgc cactcagcag ccctggccaa     1740

ctgtggccgg gcagtttccg ccagccgcct tcatgcccac acaaactgtt atgcctttgc     1800

cagctgccat gttccaaggt cccctcaccc cccttgccac cgtcccaggc acgagtgact     1860

ccaccaggtc aagtccacag accgacaagc ccaggcagaa aatgggcaaa gaaacgttta     1920

aggatttcca gatggcccag cctccgcccg tgccctcccg caaacccgac cagccctccc     1980

tcacctgtac ctcagaggcc ttctccagtt acttcaacaa agtcggggtg gcacaggata     2040

cagacgactg tgatgacttt gacatctccc agttgaattt gacccctgtg acttctacca     2100

caccatcgac caactcacct ccaaccccag cccctagaca gagctctcca tccaaatcat     2160

ctgcatccca tgccagtgat cctaccacag atgacatctt tgaagagggc tttgaaagtc     2220

ccagcaaaag cgaagagcaa gaagctcctg atggatcaca ggcctcatcc aacagtgatc     2280

catttggtga gcccagtggg gagcccagtg gtgataatat aagtccacag gccggtagct     2340

agatagcgca ggtctgggag ccagagcctc tgtacgcgca gatcaacaga cctaagaaat     2400

agcatcgatg cgagctcgtg gtgggtgctc aagactggca tggacatcag catcacgaca     2460

ggctctcttg tattctttca cctcttccca caagaaattc atgattgccc aatggaactc     2520

gctcagaaga gggaactaag catttttggc aaccaatggc agatatctat ggcagcacac     2580


<210>  890
<211>  683
<212>  DNA
<213>  homo sapiens

<400>  890
ctgcgcagat gaggggagac tcgtcaccag gcgtgcagtg ggcactgctg ggctccccca       60

tcccgtccta acccggaaca gccccgggca ggaggcgtgg aaagtcgagg gggtaaaccg      120

cgaatgtgcg ttgtgtaagc cacggcgcag ggtggggcgc gggcgggact tgggcgggcg      180

gggtgggctt ggccgagctg gcctccgggg caccgaccgc tataaggcca gtcggactgc      240

gacacagccc atcccctcga ccgctcgcgt cgcatttggc cgcctcccta ccgctccaag      300

cccagccctc agccatggca tgccccctgg atcaggccat tggcctcctc gtggccatct      360

tccacaagta ctccggcagg gagggtgaca agcacaccct gagcaagaag gagctgaagg      420

agctgatcca gaaggagctc accattggct cgaagctgca ggatgctgaa attgcaaggc      480

tgatggaaga cttggaccgg aacaaggacc aggaggtgaa cttccaggag tatgtcacct      540

tcctgggggc cttggctttg atctacaatg aagccctcaa gggctgaaaa taaataggga      600

agatggagac accctctggg ggtcctctct gagtcaaatc cagtggtggg taattgtaca      660

ataaattttt tttggtcaaa ttt                                              683


<210>  891
<211>  2676
<212>  DNA
<213>  homo sapiens

<400>  891
atattggaaa ggcgccgccg ccgcctccgc cttggagctc ggggtgtttc ggggactgcg       60

gccacaggca ggaaggcgct cctctcctgc cccgccgacg cccggccagc ccgcttcgcc      120

ctgacctgtt tcctcatgac tgcccccggc cctgctgccg acggacgtcg ccccggcgtc      180

cggatttaac acggaaaccc ggatcggagg ccgcgcgggg aggaggaggg cgacccggtc      240

ggtcctgcga ccctctcggc ccggctcggc gcctcggcgg gagccatgac ctcgctgacc      300

cagcgcagct ccggcctggt gcagcggcgc accgaggcct cccgcaacgc cgccgacaag      360

gagcgggcgg cgggcggcgg cgccggcagc agcgaggacg acgcgcagag ccgccgcgac      420

gagcaggacg acgacgacaa gggcgactcc aaggaaacgc ggctgaccct gatggaggaa      480

gtgctcctgc tgggcctcaa ggaccgcgag ggttacacat cattttggaa tgactgtata      540

tcatctggat tacgtggctg tatgttaatt gaattagcat tgagaggaag gttacaacta      600

gaggcttgtg gaatgagacg taaaagtcta ttaacaagaa aggtaatctg taagtcagat      660

gctccaacag gggatgttct tcttgatgaa gctctgaagc atgttaagga aactcagcct      720

ccagaaacgg tccagaactg gattgaatta cttagtggtg agacatggaa tccattaaaa      780

ttgcattatc agttaagaaa tgtacgggaa cgattagcta aaaacctggt ggaaaagggt      840

gtattgacaa cagagaaaca gaacttccta ctttttgaca tgacaacaca tcccctcacc      900

aataacaaca ttaagcagcg cctcatcaag aaagtacagg aagccgttct tgacaaatgg      960

gtgaatgacc ctcaccgcat ggacaggcgc ttgctggccc tcatttacct ggctcatgcc     1020

tcggacgtcc tggagaatgc ttttgctcct cttctggacg agcagtatga tttggctacc     1080

aagagagtgc ggcagcttct cgacttagac cctgaagtgg aatgtctgaa ggccaacacc     1140

aatgaggttc tgtgggcggt ggtggcggcg ttcaccaagt aactctgctc ggggtgaacc     1200

attctccttt ctctcaagta aaccagtagt ttttcttctg ttgacttctg gttttctgta     1260

atttgtactt tcccacacta taattggctt ctgttttaca aaatggtggg tggctttttc     1320

ttttttgtac gtgtacagga ttctgctggt acgagaggcc ttcctctttc tgtttttaaa     1380

aaaagtttta ctgccatatt ggcattccat tccctgttgc catcctcact gttacctgtt     1440

ttgggtttct ggtctacttt gactttcaaa gtacctccag cctcctcata cgcacagctt     1500

ttggatgacc tcagcttgag tttctccata tgtgcatgta catctagcat tctgcctaca     1560

gttcagacag aagtcacaaa aaggccttca actcaccaaa ggtaaatatc tgtatctatt     1620

aggacatttt ttacatagac ttcagttgag atgtatactt agcaaaatta tttttaaatt     1680

gaaacagcac agtaaatact taatataaaa tgtcccttgg attttgcttc ccatgtaaat     1740

ctattgtatt attacacttg ttataatttt aactataaag gtccaattgt ttcacagagc     1800

cagtttggga tgggctgcat tccatttatg ctgtatatag tttgaattat atataaatta     1860

ccccttcttc tggccacccc tgctcccatc ttagtatttt gcaagatcta atcagttgta     1920

cacctggtgc ccctcgcttg cttcaatcat ggttatttga tggcaaaatc gacctcttgt     1980

cgctgaagga gagagaaaag atgtgtgtct gattggtcct gggatttttt gagctgtgcc     2040

atttatggta ctctttgcct atgcatcccc ttgttagatt ttttttaaat tttatcttac     2100

tgtttttata atttctattg ggaagaggct tgtgaccagt accaatcttg agtttctttt     2160

tctgtccaca agtaaattaa tatctgctct gaaatgtcat ttatctactc acacattctt     2220

ggggaaaaaa atcaaatgtc agtcctagca gatgttgcat gtaaattggt agcaagtaat     2280

gattacaacc cagaggatta agaattttgt aacagaaagc tctatgtttt aattttttat     2340

atacaattag gataattagc attgtcagac tataaacctt tgctttttaa agtttatttt     2400

tactatttct ttatcacttt attgtatcat caccattggt ttcataatgt aaatactata     2460

tgttgaacaa attaaatgtc aaaatttttt attaccatag tccatgttaa tagtggggct     2520

ttcaggtgtt tagagatttt ttttgttgtt gttaacattc attgcaaaag tactagatgg     2580

tgtataactc tagagttgaa ttttaaggga ttccctaata tgtatactat ctttttatct     2640

gaagtaataa ataaacaatg atcttgaaag tgcctg                               2676


<210>  892
<211>  2676
<212>  DNA
<213>  homo sapiens

<400>  892
atattggaaa ggcgccgccg ccgcctccgc cttggagctc ggggtgtttc ggggactgcg       60

gccacaggca ggaaggcgct cctctcctgc cccgccgacg cccggccagc ccgcttcgcc      120

ctgacctgtt tcctcatgac tgcccccggc cctgctgccg acggacgtcg ccccggcgtc      180

cggatttaac acggaaaccc ggatcggagg ccgcgcgggg aggaggaggg cgacccggtc      240

ggtcctgcga ccctctcggc ccggctcggc gcctcggcgg gagccatgac ctcgctgacc      300

cagcgcagct ccggcctggt gcagcggcgc accgaggcct cccgcaacgc cgccgacaag      360

gagcgggcgg cgggcggcgg cgccggcagc agcgaggacg acgcgcagag ccgccgcgac      420

gagcaggacg acgacgacaa gggcgactcc aaggaaacgc ggctgaccct gatggaggaa      480

gtgctcctgc tgggcctcaa ggaccgcgag ggttacacat cattttggaa tgactgtata      540

tcatctggat tacgtggctg tatgttaatt gaattagcat tgagaggaag gttacaacta      600

gaggcttgtg gaatgagacg taaaagtcta ttaacaagaa aggtaatctg taagtcagat      660

gctccaacag gggatgttct tcttgatgaa gctctgaagc atgttaagga aactcagcct      720

ccagaaacgg tccagaactg gattgaatta cttagtggtg agacatggaa tccattaaaa      780

ttgcattatc agttaagaaa tgtacgggaa cgattagcta aaaacctggt ggaaaagggt      840

gtattgacaa cagagaaaca gaacttccta ctttttgaca tgacaacaca tcccctcacc      900

aataacaaca ttaagcagcg cctcatcaag aaagtacagg aagccgttct tgacaaatgg      960

gtgaatgacc ctcaccgcat ggacaggcgc ttgctggccc tcatttacct ggctcatgcc     1020

tcggacgtcc tggagaatgc ttttgctcct cttctggacg agcagtatga tttggctacc     1080

aagagagtgc ggcagcttct cgacttagac cctgaagtgg aatgtctgaa ggccaacacc     1140

aatgaggttc tgtgggcggt ggtggcggcg ttcaccaagt aactctgctc ggggtgaacc     1200

attctccttt ctctcaagta aaccagtagt ttttcttctg ttgacttctg gttttctgta     1260

atttgtactt tcccacacta taattggctt ctgttttaca aaatggtggg tggctttttc     1320

ttttttgtac gtgtacagga ttctgctggt acgagaggcc ttcctctttc tgtttttaaa     1380

aaaagtttta ctgccatatt ggcattccat tccctgttgc catcctcact gttacctgtt     1440

ttgggtttct ggtctacttt gactttcaaa gtacctccag cctcctcata cgcacagctt     1500

ttggatgacc tcagcttgag tttctccata tgtgcatgta catctagcat tctgcctaca     1560

gttcagacag aagtcacaaa aaggccttca actcaccaaa ggtaaatatc tgtatctatt     1620

aggacatttt ttacatagac ttcagttgag atgtatactt agcaaaatta tttttaaatt     1680

gaaacagcac agtaaatact taatataaaa tgtcccttgg attttgcttc ccatgtaaat     1740

ctattgtatt attacacttg ttataatttt aactataaag gtccaattgt ttcacagagc     1800

cagtttggga tgggctgcat tccatttatg ctgtatatag tttgaattat atataaatta     1860

ccccttcttc tggccacccc tgctcccatc ttagtatttt gcaagatcta atcagttgta     1920

cacctggtgc ccctcgcttg cttcaatcat ggttatttga tggcaaaatc gacctcttgt     1980

cgctgaagga gagagaaaag atgtgtgtct gattggtcct gggatttttt gagctgtgcc     2040

atttatggta ctctttgcct atgcatcccc ttgttagatt ttttttaaat tttatcttac     2100

tgtttttata atttctattg ggaagaggct tgtgaccagt accaatcttg agtttctttt     2160

tctgtccaca agtaaattaa tatctgctct gaaatgtcat ttatctactc acacattctt     2220

ggggaaaaaa atcaaatgtc agtcctagca gatgttgcat gtaaattggt agcaagtaat     2280

gattacaacc cagaggatta agaattttgt aacagaaagc tctatgtttt aattttttat     2340

atacaattag gataattagc attgtcagac tataaacctt tgctttttaa agtttatttt     2400

tactatttct ttatcacttt attgtatcat caccattggt ttcataatgt aaatactata     2460

tgttgaacaa attaaatgtc aaaatttttt attaccatag tccatgttaa tagtggggct     2520

ttcaggtgtt tagagatttt ttttgttgtt gttaacattc attgcaaaag tactagatgg     2580

tgtataactc tagagttgaa ttttaaggga ttccctaata tgtatactat ctttttatct     2640

gaagtaataa ataaacaatg atcttgaaag tgcctg                               2676


<210>  893
<211>  2329
<212>  DNA
<213>  homo sapiens

<400>  893
agccccgccc tgccccgcgc cgccaagcgg ttcccgccct cgcccagcgc ccaggtagct       60

gcgaggaaac ttttgcagcg gctgggtagc agcacgtctc ttgctcctca gggccactgc      120

caggcttgcc gagtcctggg actgctctcg ctccggctgc cactctcccg cgctctccta      180

gctccctgcg aagcaggatg gccgggaccg tgcgcaccgc gtgcttggtg gtggcgatgc      240

tgctcagctt ggacttcccg ggacaggcgc agcccccgcc gccgccgccg gacgccacct      300

gtcaccaagt ccgctccttc ttccagagac tgcagcccgg actcaagtgg gtgccagaaa      360

ctcccgtgcc aggatcagat ttgcaagtat gtctccctaa gggcccaaca tgctgctcaa      420

gaaagatgga agaaaaatac caactaacag cacgattgaa catggaacag ctgcttcagt      480

ctgcaagtat ggagctcaag ttcttaatta ttcagaatgc tgcggttttc caagaggcct      540

ttgaaattgt tgttcgccat gccaagaact acaccaatgc catgttcaag aacaactacc      600

caagcctgac tccacaagct tttgagtttg tgggtgaatt tttcacagat gtgtctctct      660

acatcttggg ttctgacatc aatgtagatg acatggtcaa tgaattgttt gacagcctgt      720

ttccagtcat ctatacccag ctaatgaacc caggcctgcc tgattcagcc ttggacatca      780

atgagtgcct ccgaggagca agacgtgacc tgaaagtatt tgggaatttc cccaagctta      840

ttatgaccca ggtttccaag tcactgcaag tcactaggat cttccttcag gctctgaatc      900

ttggaattga agtgatcaac acaactgatc acctgaagtt cagtaaggac tgtggccgaa      960

tgctcaccag aatgtggtac tgctcttact gccagggact gatgatggtt aaaccctgtg     1020

gcggttactg caatgtggtc atgcaaggct gtatggcagg tgtggtggag attgacaagt     1080

actggagaga atacattctg tcccttgaag aacttgtgaa tggcatgtac agaatctatg     1140

acatggagaa cgtactgctt ggtctctttt caacaatcca tgattctatc cagtatgtcc     1200

agaagaatgc aggaaagctg accaccacta ttggcaagtt atgtgcccat tctcaacaac     1260

gccaatatag atctgcttat tatcctgaag atctctttat tgacaagaaa gtattaaaag     1320

ttgctcatgt agaacatgaa gaaaccttat ccagccgaag aagggaacta attcagaagt     1380

tgaagtcttt catcagcttc tatagtgctt tgcctggcta catctgcagc catagccctg     1440

tggcggaaaa cgacaccctt tgctggaatg gacaagaact cgtggagaga tacagccaaa     1500

aggcagcaag gaatggaatg aaaaaccagt tcaatctcca tgagctgaaa atgaagggcc     1560

ctgagccagt ggtcagtcaa attattgaca aactgaagca cattaaccag ctcctgagaa     1620

ccatgtctat gcccaaaggt agagttctgg ataaaaacct ggatgaggaa gggtttgaaa     1680

gtggagactg cggtgatgat gaagatgagt gcattggagg ctctggtgat ggaatgataa     1740

aagtgaagaa tcagctccgc ttccttgcag aactggccta tgatctggat gtggatgatg     1800

cgcctggaaa cagtcagcag gcaactccga aggacaacga gataagcacc tttcacaacc     1860

tcgggaacgt tcattccccg ctgaagcttc tcaccagcat ggccatctcg gtggtgtgct     1920

tcttcttcct ggtgcactga ctgcctggtg cccagcacat gtgctgccct acagcaccct     1980

gtggtcttcc tcgataaagg gaaccacttt cttatttttt tctatttttt tttttttgtt     2040

atcctgtata cctcctccag ccatgaagta gaggactaac catgtgttat gttttcgaaa     2100

atcaaatggt atcttttgga ggaagataca ttttagtggt agcatataga ttgtcctttt     2160

gcaaagaaag aaaaaaaacc atcaagttgt gccaaattat tctcctatgt ttggctgcta     2220

gaacatggtt accatgtctt tctctctcac tccctccctt tctatcgttc tctctttgca     2280

tggatttctt tgaaaaaaaa taaattgctc aaataaaaaa aaaaaaaaa                 2329


<210>  894
<211>  3655
<212>  DNA
<213>  homo sapiens

<400>  894
ccgagttcag tcatactgca ccagctgagc aatgcatgga gtggacctgt aggcgacttg       60

catcgtcttc aacatgaaga tagccacagt gtcagtgctt ctgcccttgg ctctttgcct      120

catacaagat gctgccagta agaatgaaga tcaggaaatg tgccatgaat ttcaggcatt      180

tatgaaaaat ggaaaactgt tctgtcccca ggataagaaa ttttttcaaa gtcttgatgg      240

aataatgttc atcaataaat gtgccacgtg caaaatgata ctggaaaaag aagcaaaatc      300

acagaagagg gccaggcatt tagcaagagc tcccaaggct actgccccaa cagagctgaa      360

ttgtgatgat tttaaaaaag gagaaagaga tggggatttt atctgtcctg attattatga      420

agctgtttgt ggcacagatg ggaaaacata tgacaacaga tgtgcactgt gtgctgagaa      480

tgcgaaaacc gggtcccaaa ttggtgtaaa aagtgaaggg gaatgtaaga gcagtaatcc      540

agagcaggat gtatgcagtg cttttcggcc ctttgttaga gatggaagac ttggatgcac      600

aagggaaaat gatcctgttc ttggtcctga tgggaagacg catggcaata agtgtgcaat      660

gtgtgctgag ctgtttttaa aagaagctga aaatgccaag cgagagggtg aaactagaat      720

tcgacgaaat gctgaaaagg atttttgcaa ggaatatgaa aaacaagtga gaaatggaag      780

gcttttttgt acacgggaga gtgatccagt ccgtggccct gacggcagga tgcatggcaa      840

caaatgtgcc ctgtgtgctg aaattttcaa gcagcgtttt tcagaggaaa acagtaaaac      900

agatcaaaat ttgggaaaag ctgaagaaaa aactaaagtt aaaagagaaa ttgtgaaact      960

ctgcagtcaa tatcaaaatc aggcaaagaa tggaatactt ttctgtacca gagaaaatga     1020

ccctattcgt ggtccagatg ggaaaatgca tggcaacttg tgttccatgt gtcaagccta     1080

cttccaagca gaaaatgaag aaaagaaaaa ggctgaagca cgagctagaa acaaaagaga     1140

atctggaaaa gcaacctcat atgcagagct ttgcagtgaa tatcgaaagc ttgtgaggaa     1200

cggaaaactt gcttgcacca gagagaacga tcctatccag ggcccagatg ggaaagtgca     1260

tggcaacacc tgctccatgt gtgaggtctt cttccaagca gaagaagaag aaaagaaaaa     1320

gaaggaaggt aaatcaagaa acaaaagaca atctaagagt acagcttcct ttgaggagtt     1380

gtgtagtgaa taccgcaaat ccaggaaaaa cggacggctt ttttgcacca gagagaatga     1440

ccccatccag ggcccagatg gaaaaatgca tggcaacacc tgctccatgt gtgaggcctt     1500

ctttcaacaa gaagaaagag caagagcaaa ggctaaaaga gaagctgcaa aggaaatctg     1560

cagtgaattt cgggaccaag tgaggaatgg aacacttata tgcaccaggg agcataatcc     1620

tgtccgtggc ccagatggca aaatgcatgg aaacaagtgt gccatgtgtg ccagtgtgtt     1680

caaacttgaa gaagaagaga agaaaaatga taaagaagaa aaagggaaag tcgaggctga     1740

aaaagttaag agagaagcag ttcaggagct gtgcagtgaa tatcgtcatt atgtgaggaa     1800

tggacgactc ccctgtacca gagagaatga tcctattgag ggtctagatg ggaaaatcca     1860

cggcaacacc tgctccatgt gtgaagcctt cttccagcaa gaagcaaaag aaaaagaaag     1920

agctgaaccc agagcaaaag tcaaaagaga agctgaaaag gagacatgcg atgaatttcg     1980

gagacttttg caaaatggaa aacttttctg cacaagagaa aatgatcctg tgcgtggccc     2040

agatggcaag acccatggca acaagtgtgc catgtgtaag gcagtcttcc agaaagaaaa     2100

tgaggaaaga aagaggaaag aagaggaaga tcagagaaat gctgcaggac atggttccag     2160

tggtggtgga ggaggaaaca ctcaggacga atgtgctgag tatcgggaac aaatgaaaaa     2220

tggaagactc agctgtactc gggagagtga tcctgtacgt gatgctgatg gcaaatcgta     2280

caacaatcag tgtaccatgt gtaaagcaaa attggaaaga gaagcagaga gaaaaaatga     2340

gtattctcgc tccagatcaa atgggactgg atcagaatca gggaaggata catgtgatga     2400

gtttagaagc caaatgaaaa atggaaaact catctgcact cgagaaagtg accctgtccg     2460

gggtccagat ggcaagacac atggcaataa gtgtactatg tgtaaggaaa aactggaaag     2520

ggaagcagct gaaaaaaaaa agaaagagga tgaagacagg agcaatacag gagaaaggag     2580

caatacagga gaaaggagca atgacaaaga ggatctgtgt cgtgaatttc gaagcatgca     2640

gagaaatgga aagcttatct gcaccagaga aaataaccct gttcgaggcc catatggcaa     2700

gatgcacatc aataaatgtg ctatgtgtca gagcatcttt gatcgagaag ctaatgaaag     2760

aaaaaagaaa gatgaagaga aatcaagtag caagccctca aataatgcaa aggatgagtg     2820

cagtgaattt cgaaactata taaggaacaa tgaactcatc tgccctagag agaatgaccc     2880

agtgcacggt gctgatggaa agttctatac aaacaagtgc tacatgtgca gagctgtctt     2940

tctaacagaa gctttggaaa gggcaaagct tcaagaaaag ccatcccatg ttagagcttc     3000

tcaagaggaa gacagcccag actctttcag ttctctggat tctgagatgt gcaaagacta     3060

ccgagtattg cccaggatag gttatctttg tccaaaggat ttaaagcctg tctgtggtga     3120

cgatggccaa acctacaaca atccttgcat gctctgtcat gaaaacctga tacgccaaac     3180

aaatacacac atccgcagta cagggaagtg tgaggagagc agcaccccag gaaccaccgc     3240

agccagcatg cccccgtctg acgaatgaca ggaagattgt tgaaagccat gagggaaaaa     3300

ataaacccca gttctgaatc acctaccttc accatctgta tatacaaaga attcttcgga     3360

gcttgtctta tttgctatag aaaacaatac agagcttttg ggaatggact cactgatttt     3420

cagtcttttc catctctttc ctcctagact ctgtgatctg agggtataaa gacatctcca     3480

ccaagtctga gccctcaaaa tgtcctgatt acaatgctgt ctgtccaact gcctgttcaa     3540

taaaagtaaa ctcagcagaa caccctttct gggatttctt tgtcactatc tggataatag     3600

atatttgctt ttaaagaaac tgaataaact ctacccttta aaaaaaaaaa aaaaa          3655


<210>  895
<211>  4841
<212>  DNA
<213>  homo sapiens

<400>  895
agcacatcgc tgcgggctca caaagcggcc agacgctcgg cggcggcgtg tggcaggagc       60

gcaggggcgc gagccggcga tcagccttcc cggcgaccgt gccgcgggag ctcgagcaac      120

tcggactagg ggacccgggc cggcccccaa gatgccggcg atcgcggtgt tggcggcggc      180

cgccgcggcg tggtgcttcc tccaagtcga gagccggcac ctggacgcgc tcgccggagg      240

cgcgggcccc aaccacggca atttcctaga caatgaccag tggctgagca ccgtctccca      300

gtacgaccgg gacaagtact ggaaccgctt tcgagacgat gattatttca gaaactggaa      360

tcccaacaag ccctttgacc aagccctgga cccatccaag gacccctgcc tgaaggtaaa      420

atgcagccct cacaaagtgt gtgtgaccca ggactaccag accgccctgt gtgtcagccg      480

caagcacctg ctccccaggc aaaagaaggg gaacgtggcc cagaaacact gggttggacc      540

ttcgaatttg gtcaagtgca agccctgtcc cgtggcacag tcagccatgg tctgcggctc      600

agatggccac tcctacacat ccaagtgcaa attggagttc catgcttgtt ctactggcaa      660

aagcctcgcc accctctgtg atgggccctg tccctgtctc ccagagcctg agccaccaaa      720

gcacaaggca gaaaggagtg cctgcacaga caaggagttg cggaaccttg cctcccggct      780

gaaggattgg tttggagctc tccacgagga tgcgaacaga gtcatcaagc ccaccagctc      840

caacacagcc caaggcaggt ttgacactag catcctgccc atctgcaagg actccctggg      900

ctggatgttc aacaagttgg acatgaacta tgacctcctg cttgaccctt cagagatcaa      960

tgccatctac ctggataagt acgagccctg tatcaagcct cttttcaact cgtgtgactc     1020

cttcaaggat ggcaagcttt ctaacaatga gtggtgctac tgcttccaga agcctggagg     1080

tctcccttgc cagaatgaaa tgaacagaat tcagaagctg agtaagggga aaagcctgtt     1140

gggggccttc atacctcggt gtaatgagga gggctattac aaagccacac agtgccacgg     1200

cagcacgggg cagtgctggt gtgtggacaa atatgggaat gagttggctg gctccaggaa     1260

acagggtgct gtgagctgtg aagaggagca ggaaacctca ggggattttg gcagtggtgg     1320

gtccgtggtc ctgctggatg acctagaata tgaacgggag ctgggaccaa aggacaaaga     1380

ggggaagctg agggtgcaca cccgagccgt gacagaggat gatgaggatg aggatgatga     1440

caaagaggat gaggtcgggt acatatggta gtgcccacaa gaaagaggac acaagttttg     1500

cacaaaattg caagtcactt cctattcctg catttgtatc taagactcca aggcaccaag     1560

gtctcttctc cattgttgct ctctataccc gacctaaggt ttggaagaca actgcttgtt     1620

cccagaggat tctgattttg catatgtttg tatgggagaa agggtgttgt gttttttttt     1680

tgttgttgtt tattttttgg atagggaagt cattggctta attagagcct ccttcctttc     1740

tgtgagattt ttccaacaag catgtgattt acgtggaatt ctgacagtgc agggagcccc     1800

aaccctctta aatgtcaaag accctttttg attacccaca ctggtggtta ttacagcatg     1860

gttcccagcc ttacagtgtc taagtgcttc tcttgtgtcc tgtagatgtt gtgaaaaaga     1920

aaaaaacaaa aaatacacca cactgtactt tttccccctg cccccgttac tgccggtgat     1980

tattattaaa aattagtttt tttcacatca ttatatctgg cttcctataa acaacagcct     2040

taattcagtc aagactccct ttggggaatt cattttatta aaaattggtg tctggatact     2100

tccctgtaca tgcataaata tgcatgcatg tacagaaaga ctgtatgtgt gtgccttgca     2160

cacacaccca tacctctcag aaaaagtgtt tgggtatctt aaaaactcga aaaacaatga     2220

taaatttctc agcttgtcca gacctggaac aaaatttctg gaataagaaa tttgtattaa     2280

agtccttttt tgcactaaca gttggctctt gtagcctgca ggctgaggaa gtctcttctc     2340

tgtgcatcag cagagttact gaaagcctct gattgagaaa aaacctccgt ctgcctaaat     2400

cacttttctc gcagaagcca tgcgactccc acacgacacg ggcagcttca caagccatct     2460

ctttcatttc tgcttgaagc cccttggctg cagcaatcct gtctgccata ggtttcttcc     2520

ttccttacct actcaagggc tttttctaag gcatgcacac atatctcctg ttctctgaga     2580

gtaccatggt gttccttaaa agaagaaaat ttctaattct gaactcaatg ttttgctttt     2640

actccctttc tactgacaaa tcatgataag ggcacaaaag ctgtacagat tttttttttt     2700

aaccactcaa tcccaaatgg aggcctacaa agaacatcgt aataacacat ggaagcaaac     2760

cctgggtttt taagagcaaa ttctgtcccc ccctcactcc cccaagtgac aagatactaa     2820

tgaagaaagt tcttcaccat agtgtttgtt ttaactaaac tcattggagt ctagttccaa     2880

atttggtagg gtcatcatct ctacattcct taggatttct ctccctatca agctggccca     2940

gatacaagta ccaaacagta gtctctgaag ttcccccatt tccttcagta ccagtctata     3000

agctactgtc cgccactgat tttcatttat cagggtgtcc taatcagaat cagccaccca     3060

agcaagcctc tctggcccac atatctatct cttgccttcc cccatgaact tcagcctgtc     3120

cacacaaaag ccacataaac tcaagcaaga aatatgttca gccaaaacat gattatagtg     3180

gcagctgacc aatcccccat cccaaattga ccatttagat gtaccaactc accttaaatt     3240

agcatgttcc aatccagtcg gcattgcctg aatacagtag catcatacct atagttggtc     3300

ttagataaga aatgaactac ttgatatagc aaagtccttt ggcttcgtaa ataaccctga     3360

ggttttgtac ttactttccc cataggaaga cagaccatag gcaaactctg ttttgggatc     3420

tcaactccat cacctttgtt tcaatatttt ttttctctct tgaacaaaac tgagataatt     3480

tagaaaacag gtgcttaatt gcaataaaat tactatgaag tatattaaaa atcacgacat     3540

tgtaaaatct cactttagat catcaaagaa aaccattgtt actatctcct ttgagcttag     3600

gaaaatgtac aagagaacaa attaaaattg aaaaattgat ttcacttaga aaaacttcta     3660

ggaacagggt gaaccactga ttttaatttg cctaattatc ttatgacaag tatcaaatta     3720

agatgacact taaagatcct tagcattaac ttaatgatgg agaagagtgc tcaatagaca     3780

gttcccagta aggtaatgag atgccatttt cagagacatt ctaagaagat attttgattc     3840

attaaaacat taaataaaaa gccctcctca gattggaacc cccaaatcga tggagccaca     3900

ttaataatac ttttcatgcc tcactttgac atgacagcat tcgatttttt taaagatctt     3960

taatactttc catgagtact aaagattgta atgagttacc ttatccttag aagtagaatg     4020

tttgctttct tcttcttgga aatagtcctc caaaaagtcc acttgtacca gtgacaagaa     4080

gtcacttgta tagtgaccaa gtacacataa aatactgatt ataaaaatat tgtaataaac     4140

cacttcctca tttgatacag gtattaagct gaatcctcac taattcactt ttgaaaagtt     4200

cttaatgaac agttttattc ttattccatg aacagctctt ttaatacaat ttccttggta     4260

tccaacttaa atcccagaat tttgttccac catggttagt tatttgccat atgaatgtat     4320

tcttgtttct accaatattc taggcatgag aataccttaa tactgagttg gagattttgt     4380

atctgtttct cctcctttac gcccattttc ctacccacag cagcaaatga caacgtgtct     4440

gtccaggtct gtccccctgc tcatcccagg atgccactca catttttttc ttcttgttac     4500

cttgaccacg ctgtacagta acatccaaga gcccattcta cagtgggtgg ttttggtctt     4560

tttataactt tttctcaaag tcactgatgt ttgttcctgt taaatgtata gcattgtaat     4620

gagagcccat caaatcctga gtgtcagttt gttgtcccta ttgtagatga aatagtgatg     4680

tagcaaaaac ctagtaaatt ctgaatgctt ttccacgtag acttatctgg aatgtgaaca     4740

caactctttg gttaatagta aatgcttaac tgtagtcctg agtaggtgca tttctgtctg     4800

tctcaataaa ttttactttg tctgcaaaaa aaaaaaaaaa a                         4841


<210>  896
<211>  5179
<212>  DNA
<213>  homo sapiens

<400>  896
tttcagttgg aaggaggtag ggaaaataag tgctttaatt cctaggattt tggaagtaaa       60

aatggaacac cagacaaaaa tggaattttt aggcaaatgt aaagctttgt acttgggtat      120

ctcaaagtat tatacagtgt aaactatcat gattattaac caactagaag tagttctttt      180

ttttaaattt tatttttaat tttagacatg agggtcttgc tatgttgccc aggctgaagt      240

ggctactgac aggcacgatg tggcactgca gcctggaact cttgggctta agtgatcctt      300

cctgcttctt ctatcttaaa aaaaaaaagt tacgcttgct tgttaaaata tttttaaaat      360

gctgtgttta aactaagaag taaatatcca ccccacctct gacttctaaa aattatctaa      420

agtatgactg gtaagatttt tacctttaat cccacataag tctaaaattt gtgttcattt      480

ccaacaacca aagtgtgtca cttttatacc agaattttgt cctgcttata cgtttagtac      540

agaaatctca tgggagagag catccatgca tttacaaatt gttattgaat tattttattg      600

aatgatgaca cccaaactga gctagaacat aattctggct ctgctagtac atcttctgtg      660

tgatcttgga caagtcactc tactttcctt tcaattttct tttctcacag ggagataatc      720

ataaaaacga ctgtaaagta cagcacttca tagagtgctt tttgtttaaa gagctgacaa      780

taaatacgag tctcaaggtc taggaaagcc tccctcacaa cctgagctgc ttgaggacaa      840

gggattttct tttgaatcag cagtacctta tttgtgtatc tgtgatagag ttcctggtac      900

ataagaaggt ctcaataaat atgtgaattt atgaatatta ggcagattgc aaccttgaca      960

ggccactgcc tcttaaatct cctttctgtg atcttttaat atttaacatc taaaaggccg     1020

ccgctacttg ctttgggata agtatccccg gtatgtactt taaaatgccc aagcctagag     1080

aaatgattct tgtcttaagg gcaccatttc gctctcccac cgtaaagcgc cccaggcttg     1140

ggatctgggt cccaaggcta cagggaagag tttggaacgg gaagctcatc ttccggccct     1200

ctgattggcc ggctcgcact ccactcacgc ggcgcgcagc tctgattggc ctcggcggca     1260

cccctcgtcc cgcgactact ttgtgtgctg gggcggcgcg ctccggtcct cccgctcagc     1320

tggcggtctg ggctgctctg gggcagccct tcggtccact gctctgcatc gcgggcgccg     1380

ggaattttcc gagtccgagc gggttgctgc ttttgctcag aggacatcca tgaccctaat     1440

ggtctttttg ttcaagataa agtgattttt tgcctttgtt gattaactgg acaaattcag     1500

catgtagagc gcatgaagta caggacaata aagcttccta cacatatcac caggaggatc     1560

tctttgaaag attcactgca ggactaccag agagaataat ttgtctgaag catcatgtgt     1620

tgaaacaaca gaagtctatt cacctgtgca ctaactagaa acagagttac aatgttttca     1680

attctttgag ctccaggact ccagggaagt gagttgaaaa tctgaaaatg cggccatgga     1740

ctggttcctg gcgttggatt atgctcattc tttttgcctg ggggaccttg ctgttttata     1800

taggtggtca cttggtacga gataatgacc atcctgatca ctctagccga gaactgtcca     1860

agattctggc aaagcttgaa cgcttaaaac aacagaatga agacttgagg cgaatggccg     1920

aatctctccg gataccagaa ggccctattg atcaggggcc agctatagga agagtacgcg     1980

ttttagaaga gcagcttgtt aaggccaaag aacagattga aaattacaag aaacagacca     2040

gaaatggtct ggggaaggat catgaaatcc tgaggaggag gattgaaaat ggagctaaag     2100

agctctggtt tttcctacag agtgaattga agaaattaaa gaacttagaa ggaaatgaac     2160

tccaaagaca tgcagatgaa tttcttttgg atttaggaca tcatgaaagg tctataatga     2220

cggatctata ctacctcagt cagacagatg gagcaggtga ttggcgggaa aaagaggcca     2280

aagatctgac agaactggtt cagcggagaa taacatatct tcagaatccc aaggactgca     2340

gcaaagccaa aaagctggtg tgtaatatca acaaaggctg tggctatggc tgtcagctcc     2400

atcatgtggt ctactgcttc atgattgcat atggcaccca gcgaacactc atcttggaat     2460

ctcagaattg gcgctatgct actggtggat gggagactgt atttaggcct gtaagtgaga     2520

catgcacaga cagatctggc atctccactg gacactggtc aggtgaagtg aaggacaaaa     2580

atgttcaagt ggtcgagctt cccattgtag acagtcttca tccccgtcct ccatatttac     2640

ccttggctgt accagaagac ctcgcagatc gacttgtacg agtgcatggt gaccctgcag     2700

tgtggtgggt gtctcagttt gtcaaatact tgatccgccc acagccttgg ctagaaaaag     2760

aaatagaaga agccaccaag aagcttggct tcaaacatcc agttattgga gtccatgtca     2820

gacgcacaga caaagtggga acagaagctg ccttccatcc cattgaagag tacatggtgc     2880

atgttgaaga acattttcag cttcttgcac gcagaatgca agtggacaaa aaaagagtgt     2940

atttggccac agatgaccct tctttattaa aggaggcaaa aacaaagtac cccaattatg     3000

aatttattag tgataactct atttcctggt cagctggact gcacaatcga tacacagaaa     3060

attcacttcg tggagtgatc ctggatatac attttctctc tcaggcagac ttcctagtgt     3120

gtactttttc atcccaggtc tgtcgagttg cttatgaaat tatgcaaaca ctacatcctg     3180

atgcctctgc aaacttccat tctttagatg acatctacta ttttgggggc cagaatgccc     3240

acaatcaaat tgccatttat gctcaccaac cccgaactgc agatgaaatt cccatggaac     3300

ctggagatat cattggtgtg gctggaaatc attgggatgg ctattctaaa ggtgtcaaca     3360

ggaaattggg aaggacgggc ctatatccct cctacaaagt tcgagagaag atagaaacgg     3420

tcaagtaccc cacatatcct gaggctgaga aataaagctc agatggaaga gataaacgac     3480

caaactcagt tcgaccaaac tcagttcaaa ccatttcagc caaactgtag atgaagaggg     3540

ctctgatcta acaaaataag gttatatgag tagatactct cagcaccaag agcagctggg     3600

aactgacata ggcttcaatt ggtggaattc ctctttaaca agggctgcaa tgccctcata     3660

cccatgcaca gtacaataat gtactcacat ataacatgca aacaggttgt tttctacttt     3720

gcccctttca gtatgtcccc ataagacaaa cactgccata ttgtgtaatt taagtgacac     3780

agacattttg tgtgagactt aaaacatggt gcctatatct gagagacctg tgtgaactat     3840

tgagaagatc ggaacagctc cttactctga ggaagttgat tcttatttga tggtggtatt     3900

gtgaccactg aattcactcc agtcaacaga ttcagaatga gaatggacgt ttggtttttt     3960

tttgtttttg tttttgtttt ttcctttata aggttgtctg tttttttttt tttaaataat     4020

tgcatcagtt cattgacctc atcattaata agtgaagaat acatcagaaa ataaaatatt     4080

cactctccat tagaaaattt tgtaaaacaa tgccatgaac aaattcttta gtactcaatg     4140

tttctggaca ttctctttga taacaaaaaa taaattttaa aaaggaattt tgtaaagttt     4200

ctagaatttt atatcattgg atgatatgtt gatcagcctt atgtggaaga actgtgataa     4260

aaagaggagc tttttagttt ttcagcttat ttactttgtt ttttttcctg tttctgatat     4320

agtaactaat tcttaactca gagacattgg tccattttaa tactgaaaac caattttcat     4380

tggtacacat tacaaaattg ctaagaacac tgtttgggag ctttcattct catattttgg     4440

acattgtttt aattgagtga aataatcata actccttgct cccagagaag ctatcacctc     4500

catttctaaa accatttcag gtttgtttgg tagtctttct taatgtattt attatcgctt     4560

tttgtgagta gggtcctgtt ttatccagga accaatttct gccctagcct atcatgccct     4620

gcttttgaga gtaccaggta tctttgggat tgggaagctg gctgtttcag aagtatatgt     4680

ctcatagtgt gcagaacttg gtgaccaagt gagaagcggg accaatggga gactcacaat     4740

ggactgagtc ttgggattat cttttccaaa ttcttccatg ttagaatcac ttcagaaaat     4800

aagactttga tgctttgtct ctgagcatca tttttctcct cataaaaaca cttccttatt     4860

gtatgtagcc tgcctcctac agaggcctgg taggtgttac tgcattctaa aagaaaaatg     4920

tcatctctgt aggagcgact atcaggccta gtgtgaaata ttagggatcc taggcagaag     4980

agctattagt cctggccttc atatcttcac caaatgaaaa tactgtatat aaaatttcac     5040

caccaaactt aactaaattc tttttctcaa gtcaagcctc ccaaagaaaa aagaaattaa     5100

cttcctacag tgtcagcaag caattttcca tttagttttg gtacaaataa aagtcatttg     5160

aaacaaaaaa aaaaaaaaa                                                  5179


<210>  897
<211>  5443
<212>  DNA
<213>  homo sapiens

<400>  897
ctcccagcgg cggcggctgc agcgcggcgg tccgagcggg tgcaccgcgg cggaggaggc       60

agcatcccgc ggcgctgacg gtcctgggga gagcatggcg ccgaggtgcc cctggccatg      120

gccgcggcgg cggcgcctcc tggacgtgct cgcgcccctg gtcctgctgc tcggggtccg      180

cgcggcctcc gcggagccag agcgcatcag cgaggaggtg gggctgctgc agctccttgg      240

ggaccccccg ccccagcagg tcacccagac ggatgacccc gacgtcgggc tggcctacgt      300

ctttgggcca gatgccaaca gtggccaagt ggcccggtac cacttcccca gcctcttctt      360

ccgtgacttc tcactgctgt tccacatccg gccagccaca gagggcccag gggtgctgtt      420

cgccatcacg gactcggcgc aggccatggt cttgctgggc gtgaagctct ctggggtgca      480

ggacgggcac caggacatct ccctgctcta cacagaacca ggtgcaggcc agacccacac      540

agccgccagc ttccggctcc ccgccttcgt cggccagtgg acacacttag ccctcagtgt      600

ggcaggtggc tttgtggccc tctacgtgga ctgtgaggag ttccagagaa tgccgcttgc      660

tcggtcctca cggggcctgg agctggagcc tggcgccggg ctcttcgtgg ctcaggcggg      720

gggagcggac cctgacaagt tccagggggt gatcgctgag ctgaaggtgc gcagggaccc      780

ccaggtgagc cccatgcact gcctggacga ggaaggcgat gactcagatg gggcatccgg      840

agactctggc agcgggctcg gggacgcccg ggagcttctc agggaggaga cgggcgcggc      900

cctaaaaccc aggctccccg cgccaccccc cgtcaccacg ccacccttgg ctggaggcag      960

cagcacggaa gattccagaa gtgaagaagt cgaggagcag accacggtgg cttcgttagg     1020

agctcagaca cttcctggct cagattctgt ctccacgtgg gacgggagtg tccggacccc     1080

tgggggccgc gtgaaagagg gcggcctgaa ggggcagaaa ggggagccag gtgttccggg     1140

cccacctggc cgggcaggcc ccccaggatc cccatgccta cctggtcccc cgggtctccc     1200

gtgcccagtg agtcccctgg gtcctgcagg cccagcgttg caaactgtcc ccggaccaca     1260

aggaccccca gggcctccgg ggagggacgg cacccctgga agggacggcg agccgggcga     1320

ccccggtgaa gacggaaagc cgggcgacac cgggccacaa ggcttccccg ggactccagg     1380

ggacgtaggt cccaagggcg acaagggaga ccctggggtt ggagagagag ggcccccagg     1440

accccaaggg cctccagggc ccccaggacc ctccttcaga cacgacaagc tgaccttcat     1500

tgacatggag ggatctggct tcgggggcga tctggaggcc ctgcggggtc ctcgaggctt     1560

ccctggacct cccggacccc ccggtgtccc aggcctgccc ggcgagccag gccgctttgg     1620

ggtgaacagc tccgacgtcc caggacccgc cggccttcct ggtgtgcctg ggcgcgaggg     1680

tccccccggg tttcctggcc tcccgggacc cccaggccct ccgggaagag aggggccccc     1740

aggaaggact gggcagaaag gcagcctggg tgaagcaggc gccccaggac ataaggggag     1800

caagggagcc cccggtcctg ctggtgctcg tggggagagc ggcctggcag gagcccccgg     1860

acctgctgga ccaccaggcc cccctgggcc ccctgggccc ccaggaccag gactccccgc     1920

tggatttgat gacatggaag gctccggggg gcccttctgg tcaacagccc gaagcgctga     1980

tgggccacag ggacctcccg gcctgccggg acttaagggg gatcctggcg tgcctgggct     2040

gccgggggcg aagggagaag ttggagcaga tggagtcccc gggttccccg gcctccctgg     2100

cagagagggc attgctgggc cccaggggcc aaagggagac agaggcagcc ggggagaaaa     2160

gggagatcca gggaaggacg gagtcgggca gccgggcctc cctggccccc ccggaccccc     2220

gggacctgtg gtctacgtgt cggagcagga cggatccgtc ctgagcgtgc cgggacctga     2280

gggccggccg ggtttcgcag gctttcccgg acctgcagga cccaagggca acctgggctc     2340

taagggcgaa cgaggctccc cgggacccaa gggtgagaag ggtgaaccgg gcagcatctt     2400

cagccccgac ggcggtgccc tgggccctgc ccagaaagga gccaagggag agccgggctt     2460

ccgaggaccc ccgggtccat acggacggcc ggggtacaag ggagagattg gctttcctgg     2520

acggccgggt cgccccggga tgaacggatt gaaaggagag aaaggggagc cgggagatgc     2580

cagccttgga tttggcatga ggggaatgcc cggcccccca ggacctccag ggcccccagg     2640

ccctccaggg actcctgttt acgacagcaa tgtgtttgct gagtccagcc gccccgggcc     2700

tccaggattg ccagggaatc agggccctcc aggacccaag ggcgccaaag gagaagtggg     2760

cccccccgga ccaccagggc agtttccgtt tgactttctt cagttggagg ctgaaatgaa     2820

gggggagaag ggagaccgag gtgatgcagg acagaaaggc gaaagggggg agcccggggg     2880

cggcggtttc ttcggctcca gcctgcccgg cccccccggc cccccaggcc cacgtggcta     2940

ccctgggatt ccaggtccca agggagagag catccggggc cagcccggcc cacctggacc     3000

tcagggaccc cccggcatcg gctacgaggg gcgccagggc cctcccggcc ccccaggccc     3060

cccagggccc ccttcatttc ctggccctca caggcagact atcagcgttc ccggccctcc     3120

gggcccccct gggccccctg ggccccctgg aaccatgggc gcctcctcag gggtgaggct     3180

ctgggctaca cgccaggcca tgctgggcca ggtgcacgag gttcccgagg gctggctcat     3240

cttcgtggcc gagcaggagg agctctacgt ccgcgtgcag aacgggttcc ggaaggtcca     3300

gctggaggcc cggacaccac tcccacgagg gacggacaat gaagtggccg ccttgcagcc     3360

ccccgtggtg cagctgcacg acagcaaccc ctacccgcgg cgggagcacc cccaccccac     3420

cgcgcggccc tggcgggcag atgacatcct ggccagcccc cctcgcctgc ccgagcccca     3480

gccctacccc ggagccccgc accacagctc ctacgtgcac ctgcggccgg cgcgacccac     3540

aagcccaccc gcccacagcc accgcgactt ccagccggtg ctccacctgg ttgcgctcaa     3600

cagccccctg tcaggcggca tgcggggcat ccgcggggcc gacttccagt gcttccagca     3660

ggcgcgggcc gtggggctgg cgggcacctt ccgcgccttc ctgtcctcgc gcctgcagga     3720

cctgtacagc atcgtgcgcc gtgccgaccg cgcagccgtg cccatcgtca acctcaagga     3780

cgagctgctg tttcccagct gggaggctct gttctcaggc tctgagggtc cgctgaagcc     3840

cggggcacgc atcttctcct ttgacggcaa ggacgtcctg aggcacccca cctggcccca     3900

gaagagcgtg tggcatggct cggaccccaa cgggcgcagg ctgaccgaga gctactgtga     3960

gacgtggcgg acggaggctc cctcggccac gggccaggcc tcctcgctgc tggggggcag     4020

gctcctgggg cagagtgccg cgagctgcca tcacgcctac atcgtgctct gcattgagaa     4080

cagcttcatg actgcctcca agtagccacc gcctggatgc ggatggccgg agaggaccgg     4140

cggctcggag gaagccccca ccgtgggcag ggagcggccg gccagcccct ggccccagga     4200

cctggctgcc atactttcct gtatagttca cgtttcatgt aatcctcaag aaataaaagg     4260

aagccaaaga gtgtattttt ttaaaagttt aaaacagaag cctgatgctg acattcacct     4320

gccccaactc tcccctgacc tgtgagccca gctgggtcag gcagggtgca gtatcatgcc     4380

ctgtgcaacc tcttggcctg atcagaccac ggctcgattt ctccaggatt tcctgctttg     4440

ggaagccgtg ctcgccccag caggtgctga cttcatctcc cacctagcag caccgttctg     4500

tgcacaaaac ccagacctgt tagcagacag gccccgtgag gcaatgggag ctgaggccac     4560

actcagcaca aggccatctg ggctcctcca gggtgtgtgc tcgccctgcg gtagatggga     4620

gggaggctca ggtccctggg gctaggggga gccccttctg ctcagctctg ggccattctc     4680

cacagcaacc ccaggctgaa gcaggttccc aagctcagag gcgcactgtg acccccagct     4740

ccggcctgtc ctccaacacc aagcacagca gcctggggct ggcctcccaa atgagccatg     4800

agatgataca tccaaagcag acagctccac cctggccgag tccaagctgg gagattcaag     4860

ggacccatga gttggggtct ggcagcctcc catccagggc ccccatctca tgcccctggc     4920

tgggacgtgg ctcagccagc acttgtccag ctgagcgcca ggatggaaca cggccacatc     4980

aaagaggctg aggctggcac aggacatgcg gtagccagca cacagggcag tgagggaggg     5040

ctgtcatctg tgcactgccc atggacaggc tggctccaga tgcagggcag tcattggctg     5100

tctcctagga aacccatatc cttaccctcc ttgggactga aggggaaccc cggggtgccc     5160

acaggccgcc ctgcgggtga acaaagcagc cacgaggtgc aacaaggtcc tctgtcagtc     5220

acagccaccc ctgagatccg gcaacatcaa cccgagtcat tcgttctgtg gagggacaag     5280

tggactcagg gcagcgccag gctgaccaca gcacagccaa cacgcacctg cctcaggact     5340

gcgacgaaac cggtggggct ggttctgtaa ttgtgtgtga tgtgaagcca attcagacag     5400

gcaaataaaa gtgacctttt acactgaaaa aaaaaaaaaa aaa                       5443


<210>  898
<211>  10828
<212>  DNA
<213>  homo sapiens

<400>  898
ggtaccatag agttgctctg aaaacagaag atagagggag tctcggagct cgccatctcc       60

agcgatctct acattgggaa aaaacatgga gtcagctccg gcagcccccg accccgccgc      120

cagcgagcca ggcagcagcg gcgcggacgc ggccgccggc tccagggaga ccccgctgaa      180

ccaggaatcc gcccgcaaga gcgagccgcc tgccccggtg cgcagacaga gctattccag      240

caccagcaga ggtatctcag taacgaagaa gacacataca tctcaaattg aaattattcc      300

atgcaagatc tgtggagaca aatcatcagg aatccattat ggtgtcatta catgtgaagg      360

ctgcaagggc tttttcagga gaagtcagca aagcaatgcc acctactcct gtcctcgtca      420

gaagaactgt ttgattgatc gaaccagtag aaaccgctgc caacactgtc gattacagaa      480

atgccttgcc gtagggatgt ctcgagatgc tgtaaaattt ggccgaatgt caaaaaagca      540

gagagacagc ttgtatgcag aagtacagaa acaccggatg cagcagcagc agcgcgacca      600

ccagcagcag cctggagagg ctgagccgct gacgcccacc tacaacatct cggccaacgg      660

gctgacggaa cttcacgacg acctcagtaa ctacattgac gggcacaccc ctgaggggag      720

taaggcagac tccgccgtca gcagcttcta cctggacata cagccttccc cagaccagtc      780

aggtcttgat atcaatggaa tcaaaccaga accaatatgt gactacacac cagcatcagg      840

cttctttccc tactgttcgt tcaccaacgg cgagacttcc ccaactgtgt ccatggcaga      900

attagaacac cttgcacaga atatatctaa atcgcatctg gaaacctgcc aatacttgag      960

agaagagctc cagcagataa cgtggcagac ctttttacag gaagaaattg agaactatca     1020

aaacaagcag cgggaggtga tgtggcaatt gtgtgccatc aaaattacag aagctataca     1080

gtatgtggtg gagtttgcca aacgcattga tggatttatg gaactgtgtc aaaatgatca     1140

aattgtgctt ctaaaagcag gttctctaga ggtggtgttt atcagaatgt gccgtgcctt     1200

tgactctcag aacaacaccg tgtactttga tgggaagtat gccagccccg acgtcttcaa     1260

atccttaggt tgtgaagact ttattagctt tgtgtttgaa tttggaaaga gtttatgttc     1320

tatgcacctg actgaagatg aaattgcatt attttctgca tttgtactga tgtcagcaga     1380

tcgctcatgg ctgcaagaaa aggtaaaaat tgaaaaactg caacagaaaa ttcagctagc     1440

tcttcaacac gtcctacaga agaatcaccg agaagatgga atactaacaa agttaatatg     1500

caaggtgtct acattaagag ccttatgtgg acgacataca gaaaagctaa tggcatttaa     1560

agcaatatac ccagacattg tgcgacttca ttttcctcca ttatacaagg agttgttcac     1620

ttcagaattt gagccagcaa tgcaaattga tgggtaaatg ttatcaccta agcacttcta     1680

gaatgtctga agtacaaaca tgaaaaacaa acaaaaaaat taaccgagac actttatatg     1740

gccctgcaca gacctggagc gccacacact gcacatcttt tggtgatcgg ggtcaggcaa     1800

aggaggggaa acaatgaaaa caaataaaag ttgaacttgt ttttctcatg catatgattt     1860

ccattatgcc tacagatatg gacccttttt ctgtcttgac ttcttgatca ttgacctctg     1920

tttacaacag gaggagggta ctaaagtcgg aggatttcct tttcttgtag ctcactgccc     1980

acagactttc tacagagtca ccaatctgtc agtaacaaca gagagtccag caataatcgg     2040

tgactggtgt gcatagcgga ggttgcggca ttactttgca caactagctc tttgtttcat     2100

gaaggaagtt tttatttttt caccgattat tgccagtccg caggatggca tgaaaagggt     2160

ccatagcagt agcaacaata gcattataat atattacagg gtaaatgggc atgaagacta     2220

tatatagcta aaagagatat tgtttatata ttgttttaag taatataaaa tgtagttact     2280

ggtgtagctt ttcctgttga attgataagg cactttcatt ttgcaccttt ttctttaaat     2340

taaatgctag cgtgttcact gtcgtgtcgc atgtgcacca gaaacacaag tttaactgag     2400

aaggcttgga aggtacgttg ggaggtattt atgctgctgt ttacaaaatt atttttaaga     2460

gactggctgg tcatatctag aaatcaccac gttggatttt ttttttaaca tgtgaatttg     2520

gaattagaaa cggaactctc cctaaattat actttgcttt ttggtaagtt taatgataga     2580

tgtgtttatg cttcatacaa agttgaatga ttgattggcg tggtggacat ataccatcat     2640

gctcattttt tttttttaaa gctttttaaa atgccacctc atggaggcga gggggaggag     2700

aagctcattt tacacaattc agtagttaaa tatggactcg gtctcaactt ggaattctta     2760

tgctttgaga acaaatcaac aaccagaata tttattggaa tctagctttt attataagaa     2820

ggacccaaag attatatcct gagcaaatgc acactcccca tgtgaggaca tgaagtattt     2880

actttgtgaa tgtttatgtt cttggtataa tctaggaacc ctatgagttt atctcagagt     2940

gaactaattc tagatttgtt gtcaatagat gctataattc aagaatgttg ctctccatat     3000

ttgaaaaacg atggatagga gggtgaggga agcatacaat gttgaaccag tttctcttat     3060

ttaaatatta aatactttaa gcctttaaag tgaagttgat gctagctgca aacatttact     3120

cttgtattta tcttcactag gaaactgtgg actgtaattt attttattaa atatttagaa     3180

gattatttgg cttgtgtgtt caggtgagaa atactgagtt gtttttgttt aatttcatgg     3240

tttttttttt tttaatgatc cctagtgggg gaaggggaaa ggaatagtct gataaacaga     3300

tgtgcatatt ttaaaaacaa gtgacctttt gggaatgtag gcatttagac gatgatttta     3360

gtcgcactag gggtgggatt caaactactg gtcaaagacc attttgtaca gaaaagggaa     3420

catctccgat gggtgttaag gtaggagttt ccatgcagcc ctttatgtct gagaaatagt     3480

ctcctctgcc attggggtcc ctgcggaatc ttctacagga attgcagctc ttcacgtcat     3540

gctaggttac cagcatgggc ttcccagagc acttcactct gtttctaact ccactgactt     3600

ttctgacttg tttcttgagg gacttggaaa aggggaaggt attattcaca cagatgtgtg     3660

tatgaagcct aaataacatc caactttttt tccaaaaaca tagtaagagt ttaaccataa     3720

atagaagagt aatattcctt taaatttctt acaggcatgt aaaattttat gtgtttatag     3780

agagatgcta actgtcagca tatagtattt atattggggc aagaagggtt aaatcaaatc     3840

tttaatttaa gtaagcatag ttcctttaaa gatcagtagt atttatactc tgaaaagagt     3900

accaagctta gttcagttat ttattcatcc attttttttc tattgtttct cctctggggg     3960

gaaatggtgt tttgtttttg tttgagtttt gtgttttagt tttttggttt tggttttgtt     4020

ttgttttttt gtcattcaga ttcactaaat ttggggatgg ttttattaaa gtatattaac     4080

ttctttttaa ccaaagcttt ctgaatatga ccagcctcag gtgctagcgc attaaagagc     4140

aactaaacct aattccagtg tcgatttgtg aaataataaa agctaattga atttctctaa     4200

gggtgagaga gaacataatg atgaacttaa aaagaaattc cttttcccag aagggattct     4260

gcatgtacct acaaacaatc atgctctaac cacagtaata gtcatgccat ggtgacattg     4320

cttttacggt aaaccaagat aggtaatatg atgcttcttc ccaggtgttt ctgaaagaaa     4380

agcagcggtg gagcttaaga gccaagtcca ctgattgaca taataggatg gaattgtaga     4440

cagagacatg ctccatgaaa caaggaaaca actgactact atttggatct aagttgggat     4500

ctgatgttaa acaataaatt cagtttaaaa aaaatatgga gctcagaaaa ggatgtgaaa     4560

aactttgcat tttcctttct tcattattac aaaaacacct atgtgatgac ataaaatact     4620

tgggtgatat cagaacaatt atccttaata gtttttataa ttaaagtttc ctaaacttca     4680

gtctccaata gtcttttaag gattggaacc acatcactgt cagccccgct gctacaatgc     4740

ctttgtacaa tttttttaca taaggcaaat aaggcttttg tacaaagcct gaataccttc     4800

tgttccaatg gtgtccaaat ggttattata ttgtgaaaaa cctggccttg gtcacaatgc     4860

aaacaaaagt acagatgaaa gtgctttttg gacagtttgc aaattgtgtt aaagctacgg     4920

atttttttta aagtgttcag catcttaacg tgtattaaag ctatggattt ttttttaaag     4980

tcttcagcat cctaattcac cctttctaac ttaagaaaaa catgacttaa gacactgctt     5040

ctaagtttgg ttgttcttta tagtgtggat acccagttat ctgtgagcgt atgggggtgg     5100

gctgagggtc aggtgaggaa ggagtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg     5160

tgatttgcat gtgtatgatg tgtgtgcgtc ggaccgcttc taggctacta agtgtcaatg     5220

gaaaagaaaa tgtattcaaa atacttaaat caaaactaga agatggggaa aaaaagattt     5280

attctataca aagccttgtc tggaccactt tagagagact tctatttttt taacccttct     5340

ataaatattt gatggcactt gaaatattcc tgcaataaaa tgtgatttgt gtaaagaaaa     5400

aaagattttg taatgtgaaa caaagaaaga aagtaatgta attttctaaa aaaaaaaata     5460

caaacaaaca aactttgtat tattttcttg atggaatttg tctatctgtc tttggaaaac     5520

tttttatttc attgaatgtg ccatagtaga aatgtgtgtt tttagtttta gactaaggaa     5580

tagctagttg ttgtgttccg acattccaaa atgcaaaaca acctagtagt atctttcatg     5640

aaaaggttta agtagtatgt aagcttctct cattgttgct tttttgcaca tgttcttcat     5700

tcctctctag tgcaatatgt acatagagca cttgcgggtg taccttgatc cctcagggaa     5760

aaatacatat ttgtacagtt ttttggggtt tttttgtttt ttggtttttt ttgttttgcc     5820

ttttgttttt ggctaaggaa tgtcgatcga atcacttgtt attgttgagg ggcagccaga     5880

taataatcct aaagccactg tttccaacat tgattgttta aatcatatgt ccttccaatg     5940

ctattatttt aagataataa taaaaagtta ttttctgaca gttctttgtg ctgactggtg     6000

aaaaacaagg gtaaataagc accttataat tgacttactg tgaatgacaa tccatcttgg     6060

tatcaacgat agaagcccta tcattttgga gttggggtta agagtcagaa acaatgtgct     6120

cagggatctc ctaaaactct taaaacaggg tggccagtac tactgggaca aattgtgttt     6180

tttattatta ataataatga taataatact atccctccaa ggcacaagtg aactatatag     6240

aactgcgtgt gtgtaaactc tttactctcg tctcattttg ttgagtttag aacttgatgt     6300

gctcgtcagt cttgtgtttc aaaacactga ataacttcca aagcaaagtt atgccagtgt     6360

gttcaaaaga taaattaata atgtaccagc aaagagcatc attcaaagta tagtccttgc     6420

atattccagt taccatttct ctaataatta aaatattcat gataaatata tatatagcat     6480

catatgttaa aaactatttc aaattctaca tattaaggat gaaaatttta aaatccagta     6540

ataagaggag agacctgcct atcagtacag tgatataggt aaaagatgaa atatgttttt     6600

aaaataccag caattaacta ttgttttcat gggttctcct ctagaagcaa accaaaaatt     6660

ccttcatgga aaacaattct tacttctaca tgtgtagttt atatctgatg cattacaaga     6720

gctaatgttt aaagacaaaa caaaacctgc ctgtatgaca gcagcaactc gagccaacat     6780

ttagtgttac atgttatatt tttgaaatac cgttttgtta tcatattcca catattactt     6840

tccataaagt cagagaagtt caatgtaatt gttggctctg attcttccac cttgggatac     6900

acattcacaa gaagatttat atattttctt actatgatag aggaacataa tctgggaaaa     6960

cttcccatgt ctgtaagatg aaaaggatac ctttaccatg ttgtttttga taataaagaa     7020

tatggaaaat ggtagaaatc tctcctctct atgtgtattt gtatatgtgt gtatacacac     7080

acacgttgac atttttacat aacatgtgat tgccacttct tataaagtta tgatatagaa     7140

ccccatgaaa acaactttat attatagatc aaataatgtg cccagaaacg caattgcaac     7200

agtaaatctt gatctattgg taagagtcta tgatacaggt cttcattcta tccctaaaca     7260

taatgttagt aaagaggttc catcagattg tattatagag accttcctat tgctatttat     7320

ttttaagaga tgagaagact gactagcaat gtctccacag tgcaattggt ttcacttctg     7380

ggtctgtctg tctgtttgtg taggtgagat cagtgttgtc aggctctcag aataattttt     7440

aaaagaatcc agaagcctga cttcacacca agtagccatc ctagatgggc gggggggatc     7500

tccatgttca accaaaccct cagaacttag agcaataaat acattcagtc atttatttat     7560

aaatgaatga cagaatattc aatccaaata gaaacaacct tttgtcagtg atgcaacata     7620

acatggagtc ttatattgag aaagtgaata tgaatatttt aaatagatgc ctaggaaatc     7680

tgtgtttgct gtttacattt aatgtacttt gccacattag cagtaccaca cttcttttac     7740

tttcatcctt ctaagaacta atgaaagata gcttgctatt agctttgaca tgttgcacat     7800

gccattatgt tgttctctaa gaacaactaa attctctcca gtgttcatgt gtgattcctt     7860

tttcatcatt attactttaa tgtggatgaa tactatttct aggaacttga ttatcactga     7920

acagattgca tatgtaaatg cagataattc ttgagcaata tagtgaaaat gatttcacaa     7980

aaaaaatcca tatgtactgt atacatcttc ctgaatccaa aattctcctg ttatccacac     8040

agtttgaaat ctcatattaa acagtggtaa atttttaaac attaggacat tagctggctg     8100

cttctataaa tgtacctgta ttgtctgcct gctccttttg tggagatgtg tttttgtatt     8160

ggatgtttgg gccaatggga ggcttcaagc tacaacatat tttcccactt taaataatat     8220

ttaacatatg acaaacccca gacaaggctt ttaatatgta taaagaactg cagtgttagg     8280

tggtttattt gcaaactgtt ttcagtgttg tccattttta tggcaccttt aacaatattc     8340

ttgtttccaa agtacaaaaa aaataggtta aataatctag ccataactga atgtcaagca     8400

ataaaacaaa tgacttttgt gcatagactt aaaaaataca aattttagac atctgcatgt     8460

aaatgcaatc tcttgtttac tgctttcttc aacttgagca atcgattcct tatttactat     8520

taacttaaga acttgtaacg gcctgtaaac attttctctc ttactcttct ttcaaattta     8580

cctgtccctg cttttgagtc ataatattta atgttgttct gcacatctct atacagttaa     8640

ctttttggct ttcattctgt atagataaga aaatgttata ttataaacag cctactcagt     8700

gcaaatattt atctgtttat caaatccaca atatgctgta taataccggt tttactatat     8760

aatctatttt agacatagct gtttagaact agagtgtgct atttttgtgt ttttctgatg     8820

tgtggtgcta gacaagttac ttttgtgaac aacaaaaatt atccctttta ttcctagaca     8880

ataccacctt tgggtcttgt taatttcact gagtataact atatatttgt atatatatac     8940

atatatatat atatctacct atgcccaact ggcagctgta tcagagtgct ggatttggga     9000

catgcttttc tctttaaata cataatatca ttatataaat tattctagag tgtatttaat     9060

taggataaaa ttacttcctt agtatggata tttgacatct atagggtgaa tttgtttata     9120

aatatggcta tatggaaact tattagcatt tactttatgt ttgctacttg gctttacagc     9180

atatctccta agctgaaaaa taatttgcca ggccttcaag atcctaaaga aacttgttta     9240

atggagtaat atactttttt ttcttattaa ggaattgtat tactggcacc taacacagtt     9300

gtattcttag ctcctattat agataatggg catttacata aaatatccta gatggcttga     9360

tggcagaata aacctttccc ctcctacctg agtcatgaga aggatggaga cgtcctctgc     9420

cataacatgg gccataaagc aaattcgaca tgggatgttc tgtttcagta tgacctcaac     9480

cagttccatg aactgagtga aggaccttca ttttcaaagt tatttaataa gtagcttaat     9540

taagcctttc tacccattct cccaagatct actggcatta ttgaaaagca aagtttatca     9600

aatatctaac taaggatgta gttaacctta ttaaatattg attagaattg ttctgtaata     9660

ttactgaatt tgtaagatct ttagcaaaga tttttgagca atttataaat gtagagcaaa     9720

tgtttctgtt tactgcactt tttgtaactg aaggtgataa attctcaagc catgattatt     9780

ggcttccatg cactgcaata tttatccaca attctagaca ttttccattt ttgtggaaga     9840

gttgctgtta ccttaattat aaatgcaatt gtgtggttaa tgagagctaa tgctagtagt     9900

taacctttta aagtggattg gctacagttg agggagaaat ctcttttaat ataaatcaca     9960

tcattcctta actgcctctc ttggaaagag attgaaacct tttttttaaa gcacgattta    10020

gcatcctaag cttcctgagg gtagagattg tatctttttg cgtctgcaca atggctagca    10080

catgtcagca tttgacaatt gttaaatgat aacaagtgtg ccccaattaa aacgtttttc    10140

ctgggttgtt ttgttaaatt tacaaagtaa gccaagcctt acggttaaca ttctcctcta    10200

caaccaagta ttaaagccac atttaaaaag accacatgaa atgctgattc taattgtgtg    10260

taggtcttga ggattaagca cacaaatttc acaaacttct gtttgagtaa acaaactcag    10320

ccttctgtaa atatacatgc aagtttggaa acagtaatac tgtacctata aatatatgct    10380

gtctgttttg tgtacagtat gtaaaaactc cttttctgcc acactaaaaa tgcaagccat    10440

ttatgggaat cctaaaacta gtattgaact aaaactttgc taatgatctt tattagagga    10500

tcgtccaact tttcacttac cttgggtttt cttttcaatt cactcttaca ctagtctgct    10560

tatttccagc tgtttatttt attgagtcct gaatttaaaa aaaaaatatt ttgattcatt    10620

ttgtaaatac aagctgtaca aaaaagagag atttaatgtt gtcttttaaa tactccaatt    10680

ttcattctaa tatgaatgtt gttatattgt acttagaaac tgtaccttta atattacatt    10740

acctttatta aaagtgcatt gaacacatca attttagatg tgctttatgt actgttatcc    10800

tataataaaa cttcagcttc taatggaa                                       10828


<210>  899
<211>  3365
<212>  DNA
<213>  homo sapiens

<400>  899
aaaaggggga gggaactgcg gctaaggaga cgttcggtga tgggagcgca atatatgagg       60

ggatacagtg cctcaggttt aaaagagcag gaagctgagt gagaggttgc agaaaaagtg      120

tcttcgctcg gcagaggtta caggtggcat ctcagaaaga gctttgaggc tacaggctgt      180

agtcgggaag gggatcggag aactgtgtga agggacagct tagggactag cgtcctggga      240

ctagggggaa gttcgcgact ttctgaagac tggcaggaat gtgcctcctg gccctcgatg      300

cttcccccct gaggggaggc atcgtgaggg actgtggcag gcttcactga acgctgagcc      360

ggggaggtcc aactccacgt atggatccgg ggaatgagaa ttcagccaca gaggctgccg      420

cgatcataga cctagatccc gacttcgaac cccagagccg tccccgctcc tgcacctggc      480

cccttccccg accagagatc gctaaccagc cgtccgagcc gcccgaggtg gagccagatc      540

tgggggaaaa ggtacacacg gaggggcgct cagagccgat cctgttgccc tctcggctcc      600

cagagccggc cgggggcccc cagcccggaa tcctgggggc tgtaacaggt cctcggaagg      660

gaggctcccg ccggaatgcc tggggaaatc agtcatatgc agaactcatc agccaggcca      720

ttgaaagcgc cccggagaag cgactgacac ttgcccagat ctacgagtgg atggtccgta      780

ctgtacccta cttcaaggac aagggtgaca gcaacagctc agcaggatgg aagaactcga      840

tccgccacaa cctgtccctg cacagcaagt tcatcaaggt tcacaacgag gccaccggca      900

aaagctcttg gtggatgctg aaccctgagg gaggcaagag cggcaaagcc ccccgccgcc      960

gggccgcctc catggatagc agcagcaagc tgctccgggg ccgcagtaaa gcccccaaga     1020

agaaaccatc tgtgctgcca gctccacccg aaggtgccac tccaacgagc cctgtcggcc     1080

actttgccaa gtggtcaggc agcccttgct ctcgaaaccg tgaagaagcc gatatgtgga     1140

ccaccttccg tccacgaagc agttcaaatg ccagcagtgt cagcacccgg ctgtccccct     1200

tgaggccaga gtctgaggtg ctggcggagg aaataccagc ttcagtcagc agttatgcag     1260

ggggtgtccc tcccaccctc aatgaaggtc tagagctgtt agatgggctc aatctcacct     1320

cttcccattc cctgctatct cggagtggtc tctctggctt ctctttgcag catcctgggg     1380

ttaccggccc cttacacacc tacagcagct cccttttcag cccagcagag gggcccctgt     1440

cagcaggaga agggtgcttc tccagctccc aggctctgga ggccctgctc acctctgata     1500

cgccaccacc ccctgctgac gtcctcatga cccaggtaga tcccattctg tcccaggctc     1560

cgactcttct gttgctgggg gggcttcctt cctccagtaa gctggccacg ggcgtcggcc     1620

tgtgtcccaa gcccctagag gctccaggcc ccagcagtct ggttcccacc ctttctatga     1680

tagcaccacc tccagtcatg gcaagtgccc ccatccccaa ggctctgggg actcctgtgc     1740

tcacaccccc tactgaagct gcaagccaag acagaatgcc tcaggatcta gatcttgata     1800

tgtatatgga gaacctggag tgtgacatgg ataacatcat cagtgacctc atggatgagg     1860

gcgagggact ggacttcaac tttgagccag atccctgagt catgcctgga agctttgtcc     1920

cctgcttcag atgtggagcc aggcgtgttc atatctactc tttacccttg agccctcccc     1980

aggaatttgg gaccctgctt tagagctagg gtggggtctg gtcacacaca ggtgttgaag     2040

aaattataaa gataaagctg ccccatctgg ggacgatatg gggagggaga tgggagggga     2100

aaggggagag ggtttttctc actgtgccaa ttagggggta aggccccctc tcaggagcca     2160

tcatcggctt tccccattcc tacccactta ggctttgtag caagatgagc aatgctgttg     2220

gaaatgtgaa gtcaccagtg gccttacccc tgcctttggg agcaggattt ttttgtagag     2280

agtcttatct gagctgagcc aggctagctg gagcctggga tttctatgca gtggcccctt     2340

aggccagtga tgtgcggtgg gtgggctgtt taggggatct ggaagggcca aggtctgagc     2400

actggagtgg ctcgccaggc caaatcaccc ttagaaggct gcagataaca gaaaggcttt     2460

ttataaactt ttaaagaaat ataaacacaa atatagagat tttttaacca tggcagggtg     2520

ctagtggtgg gcagaatgct tttttttctt tctgaaggct ttgtgatagt gacatgatac     2580

aaacactaca gacaataaat attaggagac acagggaagt ggggagaggt ggggagtaat     2640

agtaaacaca gggaagagct cccctacgga ccaggtatag agaaaggtct atgcagaaat     2700

aggttagagt ttccctaaca aaaaagctaa cccaggtccc ctcattcctt caacttgtgc     2760

ctgggagtgt gtggtgttag ggtgcagcca cactcttcta tgacccagca tgggttagtg     2820

ctatggtggg agagtacatt gaaggcctgg aattagcttg gggccaggga agggactggg     2880

aggggagaga agagaaggag ggaaggattt aggatggtaa agttaggtac agagacctcc     2940

ctgttcaagg cccctgacag ctgtccctgc ccttcttccc cttccctgac tgcaggggtt     3000

atgtggaagt gtgtgtggca gcaggcagcg gggaggggag gaacagggaa gggggagctg     3060

gggagcttgg ctgagggtct gggaaatgag cagggatggg gggggatgtg gatcaggttt     3120

actagcacct gccagggagg ccatctgggg ctccttctcc accccagccc ccaaagcagc     3180

ccttccccca gtgccctttg catcgtcccc tcccccaccc ctgctgtggg ttcccatcat     3240

ttcctgtgtc agcgcctggc ctacccagat tgtatcatgt gctagattgg agtggggaag     3300

tgtgtcaaat caataaatga ataaattcaa taaatgccta taaccagcaa aaaaaaaaaa     3360

aaaaa                                                                 3365


<210>  900
<211>  5985
<212>  DNA
<213>  homo sapiens

<400>  900
gaagtcagcg ctgagtccca gaaaaacaga gcggggccag ctgcagcgtg tagtgcgagt       60

ggggcggacg cgcgcagccc gcccgcccgg cgaccagcaa ggagttggca tcctttggaa      120

gagttcgtga aagctttctg cccagagctc ctggaccaat gcatcttccc accaccttaa      180

accactgagc agttcagagc cccagttgca gacgacttgt cctgccacca ccatgagttc      240

tgaatgtgat ggtggttcca aagctgtgat gaatggcttg gcacctggca gcaatgggca      300

agacaaagac atggatccta caaaaatctg cactgggaag ggagcggtga ctctccgggc      360

ctcgtcttcc tacagggaaa ccccaagcag tagccctgcg agccctcagg aaacccggca      420

acacgaaagc aaaccaggtc tggagccaga gccttcttca gcagatgagt ggaggctttc      480

ttccagtgct gatgccaatg gaaatgccca gccctcttca ctcgctgcca agggctacag      540

aagtgtgcat cccaaccttc cttctgacaa gtcccaggat gccacttcct ccagtgcagc      600

ccagccggag gtaatagttg tccctctcta cctggttaat actgacagag ggcaagaagg      660

cactgccaga cctccaacac ctctggggcc tcttggctgc gtccccacaa tcccagcgac      720

tgcctctgcc gcctcacctc tgaccttccc gactctagat gatttcattc cccctcatct      780

gcagaggtgg ccccaccaca gccagccagc ccgcgcctct ggctcctttg cccccattag      840

ccagacgcca ccatccttct caccaccacc tccgctggtc cctcctgccc cggaggacct      900

ccgcagagtc tcggagcctg acctcacggg agctgtttcg agtaccgatt ccagtcctct      960

actaaatgaa gtttcttctt cccttattgg aactgattcc caagcctttc catcagttag     1020

caagccttca tccgcctatc cctccacaac gattgtcaat cctactattg tgctcttgca     1080

acacaatcga gaacagcaaa aacgactcag tagcctttca gatcctgtct cagaaagaag     1140

agtgggagag caggactcag caccaaccca ggaaaaaccc acctcacctg gcaaggctat     1200

tgaaaaaaga gcaaaggatg acagtaggcg ggtggtgaag agcactcagg acttaagcga     1260

tgtttccatg gatgaagtgg gcatcccact ccggaacact gagagatcaa aagactggta     1320

caagactatg tttaaacaga tccacaaact gaacagagat gatgattcag atctgtactc     1380

tcccagatac tcattttctg aagacacaaa atctcccctt tctgtgcctc gctcaaaaag     1440

tgagatgagc tacattgatg gtgagaaggt agtcaagagg tcggccacac tacccctccc     1500

agcccgctct tcctcactga agtcaagctc agaaagaaat gactgggaac ccccagataa     1560

gaaagtagac acaagaaaat atcgtgcaga gcccaagagc atttacgaat atcagcctgg     1620

caagtcttcc gttctgacca acgaaaagat gagctcagcc atcagcccta ctccggaaat     1680

ttcttcagag actcctggat atatatattc ttccaacttc catgcagtga agagggaatc     1740

agacggggct cctggggatc tcactagctt ggagaatgag agacaaattt ataaaagtgt     1800

cttggaaggt ggtgacatcc ctcttcaggg cctgagtggg ctcaagcgac catccagctc     1860

tgcttccact aaagattcag aatcgccaag acattttata ccagctgatt acttggaatc     1920

cacggaagaa tttattcgaa gacgtcatga tgataaagag atgagacctg ccagagccaa     1980

atttgacttt aaagctcaga cactaaagga gcttcctctg cagaagggag atattgttta     2040

catttataag caaattgatc agaactggta tgaaggagaa caccacggcc gggtgggaat     2100

cttcccacgc acctacatcg agcttcttcc tcctgctgag aaggcacagc ccaaaaagtt     2160

gacaccagtg caggttttgg aatatggaga agctattgct aagtttaact ttaatggtga     2220

tacacaagta gaaatgtcct tcagaaaggg tgagaggatc acactgctcc ggcaggtaga     2280

tgagaactgg tacgaaggga ggatcccggg gacatcccga caaggcatct tccccatcac     2340

ctacgtggat gtgatcaagc gaccactggt gaaaaaccct gtggattaca tggacctgcc     2400

tttctcctcc tccccaagtc gcagtgccac tgcaagccca cagcaacctc aagcccagca     2460

gcgaagagtc acccccgaca ggagtcaaac ctcacaagat ttatttagct atcaagcatt     2520

atatagctat ataccacaga atgatgatga gttggaactc cgcgatggag atatcgttga     2580

tgtcatggaa aaatgtgacg atggatggtt tgttggtact tcaagaagga caaagcagtt     2640

tggtactttt ccaggcaact atgtaaaacc tttgtatcta taagaagact gaaaaccatg     2700

gagattattt ttattggagg aggaagcatc attcatgaac cgatcttttt agttgagtca     2760

gtaggaaaat taatacagtg gataaagtaa gaagcaaaag acagggacag agaagtgttg     2820

tgtttaaaac ccaagcctgt ctaaggttac tgtgtattag acagggccga actagtgtgc     2880

tgagcaaaaa gaattgaagc aaattgtatt tacttagccg cttctgggag ccacttcagc     2940

ctttcccctc ccctccactt cttgggtaat ctgacctgaa gcatagtcca ggagcagagt     3000

tagccagaaa tgcctcctgc tgccccagcc ttagagagct cccatctcaa tcattgagcc     3060

tgaaggcttc aagcccaaga atgcaacaag acccccagcc tacatttctc agctcccctg     3120

gagccagctg atcctgtaac gctgctggag gtcagtctga gctaccaaga ctgtccctag     3180

acaaaggtgg agtcccccac actgcccaag accaaatccc tcactcaacc tgctgaggtg     3240

tggatgggga aacagaggca aaactgaggc acctgatgca ttcagcctgc tgtgcagcag     3300

tgccattgac tgccctgatg ttcagagaga aacgcacaca aggtttgccc atgagaattg     3360

gggagcagat ggccaagcag ataggttatg tctgttttct gagtgatgaa gtcaggaagc     3420

cctgtggctc tggaggccac ttgtggttca ttcttttccc atatccttgg cttttagaaa     3480

tggttacctt caggacagtg cagctgcatt tatcagagca ctattgctaa gttttctttt     3540

ctggcttgtg tttttctggg acagtttaga attgggaggc ctattctcat agaacaccaa     3600

aaatgatgtt cagtgattca tttaacatac accaatgtac tctggctgct ggggggacaa     3660

ccataagcaa gacatgccca gggtttgccg tggctccaga tctactccct gtaggagttc     3720

aaggatcaca caaacggtag taaccagggt tgtgaatctg agtacaccct ggcaaggctt     3780

ctcttcagac tgaagcagca attctgccac taccagcagc aaccaggacg tctgttcttt     3840

gtgggggcca gatcagaaga gagaggcccc tgtgacgccc gggctgcttg gtcacaactc     3900

tgtccaattc aaggatgttt atcggcctct cttagatcct gagtgagaca aatacagaaa     3960

tgacccattc cctgcccacc agaaactcag aggtgattgg ggagactgac acaggaaaat     4020

gaacttaatc aagagagact gtgatatgtg ctaagaaggg tgtgagggag ggagagatga     4080

attttccctg gagggatcct agaaagcatt gtcatattgc catctccatt agctcacttt     4140

taaacaacta gggtgctgga agaacctttg tctgagggta gttcatagct ggaaatactt     4200

ggaatatttt ccagagtctc taaactctca tcttccccca cagatacaca tccaagctca     4260

caaataggag tagcaattct aggtggtagg gttgtgtacg gaacccctgg ctgtctgcat     4320

atatctcaga attaccccag gaccattgtc ccaaagtcta gagtctttac aggtaggcaa     4380

aatttgtttt caatgcctgt gcctcagctg ctgtcacaaa tacccatctt aggatcccat     4440

cagcttccca tcccccacca gacagccaca gtaccctcac tttctcccta ttgttctttc     4500

aaatcctgtt ctcaggaaag aaactgccac taattcattc acactaaggt gtaaatgatt     4560

gataatagga atgagttacc tcttcccaca gacatttgtt tttaagtatg acagagcagg     4620

gccttaatcc caagggaaaa ggttatggaa ctggaggggg tgagctttct gggtagaagg     4680

agacttcctg aatttcctta aaacccagta agagtaagac ctgttgtttt ggaaggtctg     4740

ctccaccatc taagagcact gttttttttt ttttgttgtt gttgttgttt tacggtctct     4800

gagggaatat agtaaaaatg catatgcacg tgcaatttgc acggcagcat ttcaccgatt     4860

gtggactgta ttggctaatg tgtttcctgg tctttagatg caaaccatta ataacactat     4920

cttatctcat agttttttca ggggtgcttc ttgattagta gggaattttg aacacctctt     4980

taaatacagc tagaaaataa aaccaatttg taaagccaca tttgcatatg atgccagcct     5040

cacgcatttg tatatctcca gaaattcagg tatgcctcac caatttgccc gtctttaata     5100

aaatcttgtg ttaaaatttg catcacgtcg ccttcctatg tatgacgaaa caagaaacag     5160

agatttccaa ttgctctttt gtcttcagac atttagtaat ataaagtacc tatttttatg     5220

ctgaaatgtt tatacaggtt tattaatagc aagtgcaact aactggcggc atgccttgca     5280

acacattttg atatattagc catgcttccg ggtaaaggca agccccaaac tccttatctt     5340

ttgcagtctc tctgggatca gtaaaagaaa aaaaaaataa tgtgcttaag aagtgggact     5400

gtaaatatgt atatttaact ttgtatagcc catgtaccta ccttgtatag aaaaataatt     5460

ttaaaaattt gaatggaagg gggtaaagga agtcatgaag tttttttgca tttttattta     5520

aatgaaggaa ttccaaataa ctcacctaca gatttttagc acaaaaatag ccattgtaaa     5580

gtgttaaaat ttacgataag tattctattg gggaggaaag gtaactctga tctcagttac     5640

agtttttttt tcctttttaa tttcattatt ttgggttttt ggtttttgca gtcctattta     5700

tctgcagtcg tattaagtcc tattgctaga ataggttact acaaaaaagg ttatattctg     5760

aaagaaaaat aactgacatt atatataacc aattaattta aagtattgcc atttaaatta     5820

cacactgaga gcatgtccta tgcagacata gatttttctg ttcatttatt tttcttcatt     5880

gcagtggatt gatttgataa atagatgtgt tgaattacta catttgctgt acatattatt     5940

taataaactt tattcagaat tgcgtggcaa aaaaaaaaaa aaaaa                     5985


<210>  901
<211>  7852
<212>  DNA
<213>  homo sapiens

<400>  901
ggcgctgagc gagctcggag cccgcgctgt gcgcctgcgg ccggggcgcc ccgccgagcg       60

ccggtgcccc ggctcccggg ccgccttcgc cgcgcgggaa ggattcttca aaattaacag      120

aaaccaattc gggccagctg aagagaaaaa ataaaggtgg ctcccggctg cctctgctgc      180

agttcagagc aacttcagga gcttcccagc cgagagcttc aggacgcctt tcctgtccca      240

ctggcccagt tgccacaaca aacaacagag aagacggtga ccatggggga tgtgaagctg      300

gttgcctcgt cacacatttc caaaacctcc ctcagtgtgg atccctcaag agttgactcc      360

atgcccctga cagaggcccc tgctttcatt ttgccccctc ggaacctctg catcaaagaa      420

ggagccaccg ccaagttcga agggcgggtc cggggttacc cagagcccca ggtgacatgg      480

cacagaaacg ggcaacccat caccagcggg ggccgcttcc tgctggattg cggcatccgg      540

gggactttca gccttgtgat tcatgctgtc catgaggagg acaggggaaa gtatacctgt      600

gaagccacca atggcagtgg tgctcgccag gtgacagtgg agttgacagt agaaggaagt      660

tttgcgaagc agcttggtca gcctgttgtt tccaaaacct taggggatag attttcagct      720

ccagcagtgg agacccgtcc tagcatctgg ggggagtgcc caccaaagtt tgctaccaag      780

ctgggccgag ttgtggtcaa agaaggacag atgggacgat tctcctgcaa gatcactggc      840

cggccccaac cgcaggtcac ctggctcaag ggaaatgttc cactgcagcc gagtgcccgt      900

gtgtctgtgt ctgagaagaa cggcatgcag gttctggaaa tccatggagt caaccaagat      960

gacgtgggag tgtacacgtg cctggtggtg aacgggtcgg ggaaggcctc gatgtcagct     1020

gaactttcca tccaaggttt ggacagtgcc aataggtcat ttgtgagaga aacaaaagcc     1080

accaattcag atgtcaggaa agaggtgacc aatgtaatct caaaggagtc gaagctggac     1140

agtctggagg ctgcagccaa aagcaagaac tgctccagcc cccagagagg tggctcccca     1200

ccctgggctg caaacagcca gcctcagccc ccaagggagt ccaagctgga gtcatgcaag     1260

gactcgccca gaacggcccc gcagaccccg gtccttcaga agacttccag ctccatcacc     1320

ctgcaggccg caagagttca gccggaacca agagcaccag gcctgggggt cctatcacct     1380

tctggagaag agaggaagag gccagctcct ccccgtccag ccaccttccc caccaggcag     1440

cctggcctgg ggagccaaga tgttgtgagc aaggctgcta acaggagaat ccccatggag     1500

ggccagaggg attcagcatt ccccaaattt gagagcaagc cccaaagcca ggaggtcaag     1560

gaaaatcaaa ctgtcaagtt cagatgtgaa gtttccggga ttccaaagcc tgaagtggcc     1620

tggttcctgg aaggcacccc cgtgaggaga caggaaggca gcattgaggt ttatgaagat     1680

gctggctccc attacctctg cctgctgaaa gcccggacca gggacagtgg gacatacagc     1740

tgcactgctt ccaacgccca aggccagctg tcctgtagct ggaccctcca agtggaaagg     1800

cttgccgtga tggaggtggc cccctccttc tccagtgtcc tgaaggactg cgctgttatt     1860

gagggccagg attttgtgct gcagtgctcc gtacggggga ccccagtgcc ccggatcact     1920

tggctgctga atgggcagcc catccagtac gctcgctcca cctgcgaggc cggcgtggct     1980

gagctccaca tccaggatgc cctgccggag gaccatggca cctacacctg cctagctgag     2040

aatgccttgg ggcaggtgtc ctgcagcgcc tgggtcaccg tccatgaaaa gaagagtagc     2100

aggaagagtg agtaccttct gcctgtggct cccagcaagc ccactgcacc catcttcctg     2160

cagggcctct ctgatctcaa agtcatggat ggaagccagg tcactatgac tgtccaagtg     2220

tcagggaatc caccccctga agtcatctgg ctgcacaatg ggaatgagat ccaagagtca     2280

gaggacttcc actttgaaca gagaggaact cagcacagcc tttgtatcca ggaagtgttc     2340

ccggaggaca cgggcacgta cacctgcgag gcctggaaca gcgctggaga ggtccgcacc     2400

caggccgtgc tcacggtaca agagcctcac gatggcaccc agccctggtt catcagtaag     2460

cctcgctcag tgacagcctc cctgggccag agtgtcctca tctcctgcgc catagctggt     2520

gacccctttc ctaccgtgca ctggctcaga gatggcaaag ccctctgcaa agacactggc     2580

cacttcgagg tgcttcagaa tgaggacgtg ttcaccctgg ttctaaagaa ggtgcagccc     2640

tggcatgccg gccagtatga gatcctgctc aagaaccggg ttggcgaatg cagttgccag     2700

gtgtcactga tgctacagaa cagctctgcc agagcccttc cacgggggag ggagcctgcc     2760

agctgcgagg acctctgtgg tggaggagtt ggtgctgatg gtggtggtag tgaccgctat     2820

gggtccctga ggcctggctg gccagcaaga gggcagggtt ggctagagga ggaagacggc     2880

gaggacgtgc gaggggtgct gaagaggcgc gtggagacga ggcagcacac tgaggaggcg     2940

atccgccagc aggaggtgga gcagctggac ttccgagacc tcctggggaa gaaggtgagt     3000

acaaagaccc tatcggaaga cgacctgaag gagatcccag ccgagcagat ggatttccgt     3060

gccaacctgc agcggcaagt gaagccaaag actgtgtctg aggaagagag gaaggtgcac     3120

agcccccagc aggtcgattt tcgctctgtc ctggccaaga aggggacttc caagaccccc     3180

gtgcctgaga aggtgccacc gccaaaacct gccaccccgg attttcgctc agtgctgggt     3240

ggcaagaaga aattaccagc agagaatggc agcagcagtg ccgagaccct gaatgccaag     3300

gcagtggaga gttccaagcc cctgagcaat gcacagcctt cagggccctt gaaacccgtg     3360

ggcaacgcca agcctgctga gaccctgaag ccaatgggca acgccaagcc tgccgagacc     3420

ctgaagccca tgggcaatgc caagcctgat gagaacctga aatccgctag caaagaagaa     3480

ctcaagaaag acgttaagaa tgatgtgaac tgcaagagag gccatgcagg gaccacagat     3540

aatgaaaaga gatcagagag ccaggggaca gccccagcct tcaagcagaa gctgcaagat     3600

gttcatgtgg cagagggcaa gaagctgctg ctccagtgcc aggtgtcttc tgacccccca     3660

gccaccatca tctggacgct gaacggaaag accctcaaga ccaccaagtt catcatcctc     3720

tcccaggaag gctcactctg ctccgtctcc atcgagaagg cactgcctga ggacagaggc     3780

ttatacaagt gtgtagccaa gaatgacgct ggccaggcgg agtgctcctg ccaagtcacc     3840

gtggatgatg ctccagccag tgagaacacc aaggccccag agatgaaatc ccggaggccc     3900

aagagctctc ttcctcccgt gctaggaact gagagtgatg cgactgtgaa aaagaaacct     3960

gcccccaaga cacctccgaa ggcagcaatg ccccctcaga tcatccagtt ccctgaggac     4020

cagaaggtac gcgcaggaga gtcagtggag ctgtttggca aagtgacagg cactcagccc     4080

atcacctgta cctggatgaa gttccgaaag cagatccagg aaagcgagca catgaaggtg     4140

gagaacagcg agaatggcag caagctcacc atcctggccg cgcgccagga gcactgcggc     4200

tgctacacac tgctggtgga gaacaagctg ggcagcaggc aggcccaggt caacctcact     4260

gtcgtggata agccagaccc cccagctggc acaccttgtg cctctgacat tcggagctcc     4320

tcactgaccc tgtcctggta tggctcctca tatgatgggg gcagtgctgt acagtcctac     4380

agcatcgaga tctgggactc agccaacaag acgtggaagg aactagccac atgccgcagc     4440

acctctttca acgtccagga cctgctgcct gaccacgaat ataagttccg tgtacgtgca     4500

atcaacgtgt atggaaccag tgagccaagc caggagtctg aactcacaac ggtaggagag     4560

aaacctgaag agccgaagga tgaagtggag gtgtcagatg atgatgagaa ggagcccgag     4620

gttgattacc ggacagtgac aatcaatact gaacaaaaag tatctgactt ctacgacatt     4680

gaggagagat taggatctgg gaaatttgga caggtctttc gacttgtaga aaagaaaact     4740

cgaaaagtct gggcagggaa gttcttcaag gcatattcag caaaagagaa agagaatatc     4800

cggcaggaga ttagcatcat gaactgcctc caccacccta agctggtcca gtgtgtggat     4860

gcctttgaag aaaaggccaa catcgtcatg gtcctggaga tcgtgtcagg aggggagctg     4920

tttgagcgca tcattgacga ggactttgag ctgacggagc gtgagtgcat caagtacatg     4980

cggcagatct cggagggagt ggagtacatc cacaagcagg gcatcgtgca cctggacctc     5040

aagccggaga acatcatgtg tgtcaacaag acgggcacca ggatcaagct catcgacttt     5100

ggtctggcca ggaggctgga gaatgcgggg tctctgaagg tcctctttgg caccccagaa     5160

tttgtggctc ctgaagtgat caactatgag cccatcggct acgccacaga catgtggagc     5220

atcggggtca tctgctacat cctagtcagt ggcctttccc ccttcatggg agacaacgat     5280

aacgaaacct tggccaacgt tacctcagcc acctgggact tcgacgacga ggcattcgat     5340

gagatctccg acgatgccaa ggatttcatc agcaatctgc tgaagaaaga tatgaaaaac     5400

cgcctggact gcacgcagtg ccttcagcat ccatggctaa tgaaagatac caagaacatg     5460

gaggccaaga aactctccaa ggaccggatg aagaagtaca tggcaagaag gaaatggcag     5520

aaaacgggca atgctgtgag agccattgga agactgtcct ctatggcaat gatctcaggg     5580

ctcagtggca ggaaatcctc aacagggtca ccaaccagcc cgctcaatgc agaaaaacta     5640

gaatctgaag aagatgtgtc ccaagctttc cttgaggctg ttgctgagga aaagcctcat     5700

gtaaaaccct atttctctaa gaccattcgc gatttagaag ttgtggaggg aagtgctgct     5760

agatttgact gcaagattga aggataccca gaccccgagg ttgtctggtt caaagatgac     5820

cagtcaatca gggagtcccg ccacttccag atagactacg atgaggacgg gaactgctct     5880

ttaattatta gtgatgtttg cggggatgac gatgccaagt acacctgcaa ggctgtcaac     5940

agtcttggag aagccacctg cacagcagag ctcattgtgg aaacgatgga ggaaggtgaa     6000

ggggaagggg aagaggaaga agagtgaaac aaagccagag aaaagcagtt tctaagtcat     6060

attaaaagga ctatttctct aaaactcaaa aaaaaaaaaa aaactcaaga tagtaaaagc     6120

acctagtgtg atagattatc ggttaggtca tttgtgggtt gattcttcag aaacagcagt     6180

tgatacctag cagcgttatt gatgggcatt aatctatgtt agttggcacc ttaagatact     6240

agtgcagcta gatttcattt agggaaatca ccagtaactt gactgaccaa ttgattttag     6300

agagaaagta accaaaccaa atatttatct gggcaaagtc ataaattctc cacttgaatg     6360

cgctcatgaa aaataaggcc aaaacaagag ttctgggcca cagctcagcc cagagggttc     6420

ctggggatgg gaggcctctc tctccccacc ccctgactct agagaactgg gttttctccc     6480

agtactccag caattcattt ctgaaagcag ttgagccact ttattccaaa gtacactgca     6540

gatgttcaaa ctctccattt ctctttcccc ttccacctgc cagttttgct gactctcaac     6600

ttgtcatgag tgtaagcatt aaggacatta tgcttcttcg attctgaaga caggtccctg     6660

ctcatggatg actctggctt ccttaggaaa atatttttct tccaaaatca gtaggaaatc     6720

taaacttatc ccctctttgc agatgtctag cagcttcaga catttggtta agaacccatg     6780

ggaaaaaaaa aatccttgct aatgtggttt cctttgtaaa ccaggattct tatttgtgct     6840

gttatagaat atcagctctg aacgtgtggt aaagattttt gtgtttgaat ataggagaaa     6900

tcagtttgct gaaaagttag tcttaattat ctattggcca cgatgaaaca gatttcaact     6960

gataaagagc tggagaactc catgtacttt ggaatctcct ccaagatagc cagagtttaa     7020

tacatcttca ttctcaacac tctccaaaga acttgaccta ccttatgggt tccatatttt     7080

tcttcttaaa tgtgcatcaa tcatgccttg cccccaacct ttaaatatat tcttagacct     7140

ggtaaatgca ctcagacttg cgtctttagg aatttttaac tttctttcac tacattggca     7200

cttaaatttt ttctttataa agctttttga aggtcataaa caaagaccat aattgatgat     7260

agacctaata catttcctct gtgtgtgtgt gtaacattcc aaatactttt tttttctttt     7320

ccactgtttg taaggtgcaa caatttaata tttttaaggg actttttaag agttccttaa     7380

gaaccaattt aaaattactt cagtgcaatc ctacacagta tcaacattag aattttgata     7440

ttagtcttat gttatcttcc attctatttt tatctgcttt ttgctgctag tttcaaactg     7500

ccagtatttt tccttttgct tttaaaatag ttacaatatt tttcatgata gccacagtat     7560

tgccacagtt tattataata aagggttttt atttgattta gcgcattcaa agcttttttc     7620

tatcactttt gtgttcagaa tataaccttt gtgtgcgtgt atgttgtgtg tgtgcatgtg     7680

tggcgtatat gtgtgttaca ggttaatgcc ttcttggaat tgtgttaatg ttctcttggt     7740

ttattatgcc atcagaatgg taaatgagaa cactacaact gtagtcagct cacaattttt     7800

aaataaagga taccacagtg catgctgttt gttcaaaaaa aaaaaaaaaa aa             7852


<210>  902
<211>  7699
<212>  DNA
<213>  homo sapiens

<400>  902
ggcgctgagc gagctcggag cccgcgctgt gcgcctgcgg ccggggcgcc ccgccgagcg       60

ccggtgcccc ggctcccggg ccgccttcgc cgcgcgggaa ggattcttca aaattaacag      120

aaaccaattc gggccagctg aagagaaaaa ataaaggtgg ctcccggctg cctctgctgc      180

agttcagagc aacttcagga gcttcccagc cgagagcttc aggacgcctt tcctgtccca      240

ctggcccagt tgccacaaca aacaacagag aagacggtga ccatggggga tgtgaagctg      300

gttgcctcgt cacacatttc caaaacctcc ctcagtgtgg atccctcaag agttgactcc      360

atgcccctga cagaggcccc tgctttcatt ttgccccctc ggaacctctg catcaaagaa      420

ggagccaccg ccaagttcga agggcgggtc cggggttacc cagagcccca ggtgacatgg      480

cacagaaacg ggcaacccat caccagcggg ggccgcttcc tgctggattg cggcatccgg      540

gggactttca gccttgtgat tcatgctgtc catgaggagg acaggggaaa gtatacctgt      600

gaagccacca atggcagtgg tgctcgccag gtgacagtgg agttgacagt agaaggaagt      660

tttgcgaagc agcttggtca gcctgttgtt tccaaaacct taggggatag attttcagct      720

ccagcagtgg agacccgtcc tagcatctgg ggggagtgcc caccaaagtt tgctaccaag      780

ctgggccgag ttgtggtcaa agaaggacag atgggacgat tctcctgcaa gatcactggc      840

cggccccaac cgcaggtcac ctggctcaag ggaaatgttc cactgcagcc gagtgcccgt      900

gtgtctgtgt ctgagaagaa cggcatgcag gttctggaaa tccatggagt caaccaagat      960

gacgtgggag tgtacacgtg cctggtggtg aacgggtcgg ggaaggcctc gatgtcagct     1020

gaactttcca tccaaggttt ggacagtgcc aataggtcat ttgtgagaga aacaaaagcc     1080

accaattcag atgtcaggaa agaggtgacc aatgtaatct caaaggagtc gaagctggac     1140

agtctggagg ctgcagccaa aagcaagaac tgctccagcc cccagagagg tggctcccca     1200

ccctgggctg caaacagcca gcctcagccc ccaagggagt ccaagctgga gtcatgcaag     1260

gactcgccca gaacggcccc gcagaccccg gtccttcaga agacttccag ctccatcacc     1320

ctgcaggccg caagagttca gccggaacca agagcaccag gcctgggggt cctatcacct     1380

tctggagaag agaggaagag gccagctcct ccccgtccag ccaccttccc caccaggcag     1440

cctggcctgg ggagccaaga tgttgtgagc aaggctgcta acaggagaat ccccatggag     1500

ggccagaggg attcagcatt ccccaaattt gagagcaagc cccaaagcca ggaggtcaag     1560

gaaaatcaaa ctgtcaagtt cagatgtgaa gtttccggga ttccaaagcc tgaagtggcc     1620

tggttcctgg aaggcacccc cgtgaggaga caggaaggca gcattgaggt ttatgaagat     1680

gctggctccc attacctctg cctgctgaaa gcccggacca gggacagtgg gacatacagc     1740

tgcactgctt ccaacgccca aggccagctg tcctgtagct ggaccctcca agtggaaagg     1800

cttgccgtga tggaggtggc cccctccttc tccagtgtcc tgaaggactg cgctgttatt     1860

gagggccagg attttgtgct gcagtgctcc gtacggggga ccccagtgcc ccggatcact     1920

tggctgctga atgggcagcc catccagtac gctcgctcca cctgcgaggc cggcgtggct     1980

gagctccaca tccaggatgc cctgccggag gaccatggca cctacacctg cctagctgag     2040

aatgccttgg ggcaggtgtc ctgcagcgcc tgggtcaccg tccatgaaaa gaagagtagc     2100

aggaagagtg agtaccttct gcctgtggct cccagcaagc ccactgcacc catcttcctg     2160

cagggcctct ctgatctcaa agtcatggat ggaagccagg tcactatgac tgtccaagtg     2220

tcagggaatc caccccctga agtcatctgg ctgcacaatg ggaatgagat ccaagagtca     2280

gaggacttcc actttgaaca gagaggaact cagcacagcc tttgtatcca ggaagtgttc     2340

ccggaggaca cgggcacgta cacctgcgag gcctggaaca gcgctggaga ggtccgcacc     2400

caggccgtgc tcacggtaca agagcctcac gatggcaccc agccctggtt catcagtaag     2460

cctcgctcag tgacagcctc cctgggccag agtgtcctca tctcctgcgc catagctggt     2520

gacccctttc ctaccgtgca ctggctcaga gatggcaaag ccctctgcaa agacactggc     2580

cacttcgagg tgcttcagaa tgaggacgtg ttcaccctgg ttctaaagaa ggtgcagccc     2640

tggcatgccg gccagtatga gatcctgctc aagaaccggg ttggcgaatg cagttgccag     2700

gtgtcactga tgctacagaa cagctctgcc agagcccttc cacgggggag ggagcctgcc     2760

agctgcgagg acctctgtgg tggaggagtt ggtgctgatg gtggtggtag tgaccgctat     2820

gggtccctga ggcctggctg gccagcaaga gggcagggtt ggctagagga ggaagacggc     2880

gaggacgtgc gaggggtgct gaagaggcgc gtggagacga ggcagcacac tgaggaggcg     2940

atccgccagc aggaggtgga gcagctggac ttccgagacc tcctggggaa gaaggtgagt     3000

acaaagaccc tatcggaaga cgacctgaag gagatcccag ccgagcagat ggatttccgt     3060

gccaacctgc agcggcaagt gaagccaaag actgtgtctg aggaagagag gaaggtgcac     3120

agcccccagc aggtcgattt tcgctctgtc ctggccaaga aggggacttc caagaccccc     3180

gtgcctgaga aggtgccacc gccaaaacct gccaccccgg attttcgctc agtgctgggt     3240

ggcaagaaga aattaccagc agagaatggc agcagcagtg ccgagaccct gaatgccaag     3300

gcagtggaga gttccaagcc cctgagcaat gcacagcctt cagggccctt gaaacccgtg     3360

ggcaacgcca agcctgctga gaccctgaag ccaatgggca acgccaagcc tgccgagacc     3420

ctgaagccca tgggcaatgc caagcctgat gagaacctga aatccgctag caaagaagaa     3480

ctcaagaaag acgttaagaa tgatgtgaac tgcaagagag gccatgcagg gaccacagat     3540

aatgaaaaga gatcagagag ccaggggaca gccccagcct tcaagcagaa gctgcaagat     3600

gttcatgtgg cagagggcaa gaagctgctg ctccagtgcc aggtgtcttc tgacccccca     3660

gccaccatca tctggacgct gaacggaaag accctcaaga ccaccaagtt catcatcctc     3720

tcccaggaag gctcactctg ctccgtctcc atcgagaagg cactgcctga ggacagaggc     3780

ttatacaagt gtgtagccaa gaatgacgct ggccaggcgg agtgctcctg ccaagtcacc     3840

gtggatgatg ctccagccag tgagaacacc aaggccccag agatgaaatc ccggaggccc     3900

aagagctctc ttcctcccgt gctaggaact gagagtgatg cgactgtgaa aaagaaacct     3960

gcccccaaga cacctccgaa ggcagcaatg ccccctcaga tcatccagtt ccctgaggac     4020

cagaaggtac gcgcaggaga gtcagtggag ctgtttggca aagtgacagg cactcagccc     4080

atcacctgta cctggatgaa gttccgaaag cagatccagg aaagcgagca catgaaggtg     4140

gagaacagcg agaatggcag caagctcacc atcctggccg cgcgccagga gcactgcggc     4200

tgctacacac tgctggtgga gaacaagctg ggcagcaggc aggcccaggt caacctcact     4260

gtcgtggata agccagaccc cccagctggc acaccttgtg cctctgacat tcggagctcc     4320

tcactgaccc tgtcctggta tggctcctca tatgatgggg gcagtgctgt acagtcctac     4380

agcatcgaga tctgggactc agccaacaag acgtggaagg aactagccac atgccgcagc     4440

acctctttca acgtccagga cctgctgcct gaccacgaat ataagttccg tgtacgtgca     4500

atcaacgtgt atggaaccag tgagccaagc caggagtctg aactcacaac ggtaggagag     4560

aaacctgaag agccgaagga tgaagtggag gtgtcagatg atgatgagaa ggagcccgag     4620

gttgattacc ggacagtgac aatcaatact gaacaaaaag tatctgactt ctacgacatt     4680

gaggagagat taggatctgg gaaatttgga caggtctttc gacttgtaga aaagaaaact     4740

cgaaaagtct gggcagggaa gttcttcaag gcatattcag caaaagagaa agagaatatc     4800

cggcaggaga ttagcatcat gaactgcctc caccacccta agctggtcca gtgtgtggat     4860

gcctttgaag aaaaggccaa catcgtcatg gtcctggaga tcgtgtcagg aggggagctg     4920

tttgagcgca tcattgacga ggactttgag ctgacggagc gtgagtgcat caagtacatg     4980

cggcagatct cggagggagt ggagtacatc cacaagcagg gcatcgtgca cctggacctc     5040

aagccggaga acatcatgtg tgtcaacaag acgggcacca ggatcaagct catcgacttt     5100

ggtctggcca ggaggctgga gaatgcgggg tctctgaagg tcctctttgg caccccagaa     5160

tttgtggctc ctgaagtgat caactatgag cccatcggct acgccacaga catgtggagc     5220

atcggggtca tctgctacat cctaaaccgc ctggactgca cgcagtgcct tcagcatcca     5280

tggctaatga aagataccaa gaacatggag gccaagaaac tctccaagga ccggatgaag     5340

aagtacatgg caagaaggaa atggcagaaa acgggcaatg ctgtgagagc cattggaaga     5400

ctgtcctcta tggcaatgat ctcagggctc agtggcagga aatcctcaac agggtcacca     5460

accagcccgc tcaatgcaga aaaactagaa tctgaagaag atgtgtccca agctttcctt     5520

gaggctgttg ctgaggaaaa gcctcatgta aaaccctatt tctctaagac cattcgcgat     5580

ttagaagttg tggagggaag tgctgctaga tttgactgca agattgaagg atacccagac     5640

cccgaggttg tctggttcaa agatgaccag tcaatcaggg agtcccgcca cttccagata     5700

gactacgatg aggacgggaa ctgctcttta attattagtg atgtttgcgg ggatgacgat     5760

gccaagtaca cctgcaaggc tgtcaacagt cttggagaag ccacctgcac agcagagctc     5820

attgtggaaa cgatggagga aggtgaaggg gaaggggaag aggaagaaga gtgaaacaaa     5880

gccagagaaa agcagtttct aagtcatatt aaaaggacta tttctctaaa actcaaaaaa     5940

aaaaaaaaaa ctcaagatag taaaagcacc tagtgtgata gattatcggt taggtcattt     6000

gtgggttgat tcttcagaaa cagcagttga tacctagcag cgttattgat gggcattaat     6060

ctatgttagt tggcacctta agatactagt gcagctagat ttcatttagg gaaatcacca     6120

gtaacttgac tgaccaattg attttagaga gaaagtaacc aaaccaaata tttatctggg     6180

caaagtcata aattctccac ttgaatgcgc tcatgaaaaa taaggccaaa acaagagttc     6240

tgggccacag ctcagcccag agggttcctg gggatgggag gcctctctct ccccaccccc     6300

tgactctaga gaactgggtt ttctcccagt actccagcaa ttcatttctg aaagcagttg     6360

agccacttta ttccaaagta cactgcagat gttcaaactc tccatttctc tttccccttc     6420

cacctgccag ttttgctgac tctcaacttg tcatgagtgt aagcattaag gacattatgc     6480

ttcttcgatt ctgaagacag gtccctgctc atggatgact ctggcttcct taggaaaata     6540

tttttcttcc aaaatcagta ggaaatctaa acttatcccc tctttgcaga tgtctagcag     6600

cttcagacat ttggttaaga acccatggga aaaaaaaaat ccttgctaat gtggtttcct     6660

ttgtaaacca ggattcttat ttgtgctgtt atagaatatc agctctgaac gtgtggtaaa     6720

gatttttgtg tttgaatata ggagaaatca gtttgctgaa aagttagtct taattatcta     6780

ttggccacga tgaaacagat ttcaactgat aaagagctgg agaactccat gtactttgga     6840

atctcctcca agatagccag agtttaatac atcttcattc tcaacactct ccaaagaact     6900

tgacctacct tatgggttcc atatttttct tcttaaatgt gcatcaatca tgccttgccc     6960

ccaaccttta aatatattct tagacctggt aaatgcactc agacttgcgt ctttaggaat     7020

ttttaacttt ctttcactac attggcactt aaattttttc tttataaagc tttttgaagg     7080

tcataaacaa agaccataat tgatgataga cctaatacat ttcctctgtg tgtgtgtgta     7140

acattccaaa tacttttttt ttcttttcca ctgtttgtaa ggtgcaacaa tttaatattt     7200

ttaagggact ttttaagagt tccttaagaa ccaatttaaa attacttcag tgcaatccta     7260

cacagtatca acattagaat tttgatatta gtcttatgtt atcttccatt ctatttttat     7320

ctgctttttg ctgctagttt caaactgcca gtatttttcc ttttgctttt aaaatagtta     7380

caatattttt catgatagcc acagtattgc cacagtttat tataataaag ggtttttatt     7440

tgatttagcg cattcaaagc ttttttctat cacttttgtg ttcagaatat aacctttgtg     7500

tgcgtgtatg ttgtgtgtgt gcatgtgtgg cgtatatgtg tgttacaggt taatgccttc     7560

ttggaattgt gttaatgttc tcttggttta ttatgccatc agaatggtaa atgagaacac     7620

tacaactgta gtcagctcac aatttttaaa taaaggatac cacagtgcat gctgtttgtt     7680

caaaaaaaaa aaaaaaaaa                                                  7699


<210>  903
<211>  2676
<212>  DNA
<213>  homo sapiens

<400>  903
ttggagctgt ctcagcctgc agttgcttta tataaaccat cccttttatg ggagttgaag       60

cactgtatga aaagggtttt tgtctcatgt tgaccttgtt tagtcacatt aacgcacaca      120

tcagttccag gccccattcc attctctgaa catcttctga cacactgaca gtgctgagca      180

gagcaaggtt gggttcgctc ctctggcaga acctcggctc tcaggaggtc cttgttccag      240

ggaacagctg cttctctggg gctgggctct actccctgca gcccctcgca ctacccagct      300

ggaaccaggg acaacgcctg agtccaaccc tcgtgtctat tttccagaaa acgggcaatg      360

ctgtgagagc cattggaaga ctgtcctcta tggcaatgat ctcagggctc agtggcagga      420

aatcctcaac agggtcacca accagcccgc tcaatgcaga aaaactagaa tctgaagatg      480

tgtcccaagc tttccttgag gctgttgctg aggaaaagcc tcatgtaaaa ccctatttct      540

ctaagaccat tcgcgattta gaagttgtgg agggaagtgc tgctagattt gactgcaaga      600

ttgaaggata cccagacccc gaggttgtct ggttcaaaga tgaccagtca atcagggagt      660

cccgccactt ccagatagac tacgatgagg acgggaactg ctctttaatt attagtgatg      720

tttgcgggga tgacgatgcc aagtacacct gcaaggctgt caacagtctt ggagaagcca      780

cctgcacagc agagctcatt gtggaaacga tggaggaagg tgaaggggaa ggggaagagg      840

aagaagagtg aaacaaagcc agagaaaagc agtttctaag tcatattaaa aggactattt      900

ctctaaaact caaaaaaaaa aaaaaaactc aagatagtaa aagcacctag tgtgatagat      960

tatcggttag gtcatttgtg ggttgattct tcagaaacag cagttgatac ctagcagcgt     1020

tattgatggg cattaatcta tgttagttgg caccttaaga tactagtgca gctagatttc     1080

atttagggaa atcaccagta acttgactga ccaattgatt ttagagagaa agtaaccaaa     1140

ccaaatattt atctgggcaa agtcataaat tctccacttg aatgcgctca tgaaaaataa     1200

ggccaaaaca agagttctgg gccacagctc agcccagagg gttcctgggg atgggaggcc     1260

tctctctccc caccccctga ctctagagaa ctgggttttc tcccagtact ccagcaattc     1320

atttctgaaa gcagttgagc cactttattc caaagtacac tgcagatgtt caaactctcc     1380

atttctcttt ccccttccac ctgccagttt tgctgactct caacttgtca tgagtgtaag     1440

cattaaggac attatgcttc ttcgattctg aagacaggtc cctgctcatg gatgactctg     1500

gcttccttag gaaaatattt ttcttccaaa atcagtagga aatctaaact tatcccctct     1560

ttgcagatgt ctagcagctt cagacatttg gttaagaacc catgggaaaa aaaaaatcct     1620

tgctaatgtg gtttcctttg taaaccagga ttcttatttg tgctgttata gaatatcagc     1680

tctgaacgtg tggtaaagat ttttgtgttt gaatatagga gaaatcagtt tgctgaaaag     1740

ttagtcttaa ttatctattg gccacgatga aacagatttc aactgataaa gagctggaga     1800

actccatgta ctttggaatc tcctccaaga tagccagagt ttaatacatc ttcattctca     1860

acactctcca aagaacttga cctaccttat gggttccata tttttcttct taaatgtgca     1920

tcaatcatgc cttgccccca acctttaaat atattcttag acctggtaaa tgcactcaga     1980

cttgcgtctt taggaatttt taactttctt tcactacatt ggcacttaaa ttttttcttt     2040

ataaagcttt ttgaaggtca taaacaaaga ccataattga tgatagacct aatacatttc     2100

ctctgtgtgt gtgtgtaaca ttccaaatac tttttttttc ttttccactg tttgtaaggt     2160

gcaacaattt aatattttta agggactttt taagagttcc ttaagaacca atttaaaatt     2220

acttcagtgc aatcctacac agtatcaaca ttagaatttt gatattagtc ttatgttatc     2280

ttccattcta tttttatctg ctttttgctg ctagtttcaa actgccagta tttttccttt     2340

tgcttttaaa atagttacaa tatttttcat gatagccaca gtattgccac agtttattat     2400

aataaagggt ttttatttga tttagcgcat tcaaagcttt tttctatcac ttttgtgttc     2460

agaatataac ctttgtgtgc gtgtatgttg tgtgtgtgca tgtgtggcgt atatgtgtgt     2520

tacaggttaa tgccttcttg gaattgtgtt aatgttctct tggtttatta tgccatcaga     2580

atggtaaatg agaacactac aactgtagtc agctcacaat ttttaaataa aggataccac     2640

agtgcatgct gtttgttcaa aaaaaaaaaa aaaaaa                               2676


<210>  904
<211>  2679
<212>  DNA
<213>  homo sapiens

<400>  904
ttggagctgt ctcagcctgc agttgcttta tataaaccat cccttttatg ggagttgaag       60

cactgtatga aaagggtttt tgtctcatgt tgaccttgtt tagtcacatt aacgcacaca      120

tcagttccag gccccattcc attctctgaa catcttctga cacactgaca gtgctgagca      180

gagcaaggtt gggttcgctc ctctggcaga acctcggctc tcaggaggtc cttgttccag      240

ggaacagctg cttctctggg gctgggctct actccctgca gcccctcgca ctacccagct      300

ggaaccaggg acaacgcctg agtccaaccc tcgtgtctat tttccagaaa acgggcaatg      360

ctgtgagagc cattggaaga ctgtcctcta tggcaatgat ctcagggctc agtggcagga      420

aatcctcaac agggtcacca accagcccgc tcaatgcaga aaaactagaa tctgaagaag      480

atgtgtccca agctttcctt gaggctgttg ctgaggaaaa gcctcatgta aaaccctatt      540

tctctaagac cattcgcgat ttagaagttg tggagggaag tgctgctaga tttgactgca      600

agattgaagg atacccagac cccgaggttg tctggttcaa agatgaccag tcaatcaggg      660

agtcccgcca cttccagata gactacgatg aggacgggaa ctgctcttta attattagtg      720

atgtttgcgg ggatgacgat gccaagtaca cctgcaaggc tgtcaacagt cttggagaag      780

ccacctgcac agcagagctc attgtggaaa cgatggagga aggtgaaggg gaaggggaag      840

aggaagaaga gtgaaacaaa gccagagaaa agcagtttct aagtcatatt aaaaggacta      900

tttctctaaa actcaaaaaa aaaaaaaaaa ctcaagatag taaaagcacc tagtgtgata      960

gattatcggt taggtcattt gtgggttgat tcttcagaaa cagcagttga tacctagcag     1020

cgttattgat gggcattaat ctatgttagt tggcacctta agatactagt gcagctagat     1080

ttcatttagg gaaatcacca gtaacttgac tgaccaattg attttagaga gaaagtaacc     1140

aaaccaaata tttatctggg caaagtcata aattctccac ttgaatgcgc tcatgaaaaa     1200

taaggccaaa acaagagttc tgggccacag ctcagcccag agggttcctg gggatgggag     1260

gcctctctct ccccaccccc tgactctaga gaactgggtt ttctcccagt actccagcaa     1320

ttcatttctg aaagcagttg agccacttta ttccaaagta cactgcagat gttcaaactc     1380

tccatttctc tttccccttc cacctgccag ttttgctgac tctcaacttg tcatgagtgt     1440

aagcattaag gacattatgc ttcttcgatt ctgaagacag gtccctgctc atggatgact     1500

ctggcttcct taggaaaata tttttcttcc aaaatcagta ggaaatctaa acttatcccc     1560

tctttgcaga tgtctagcag cttcagacat ttggttaaga acccatggga aaaaaaaaat     1620

ccttgctaat gtggtttcct ttgtaaacca ggattcttat ttgtgctgtt atagaatatc     1680

agctctgaac gtgtggtaaa gatttttgtg tttgaatata ggagaaatca gtttgctgaa     1740

aagttagtct taattatcta ttggccacga tgaaacagat ttcaactgat aaagagctgg     1800

agaactccat gtactttgga atctcctcca agatagccag agtttaatac atcttcattc     1860

tcaacactct ccaaagaact tgacctacct tatgggttcc atatttttct tcttaaatgt     1920

gcatcaatca tgccttgccc ccaaccttta aatatattct tagacctggt aaatgcactc     1980

agacttgcgt ctttaggaat ttttaacttt ctttcactac attggcactt aaattttttc     2040

tttataaagc tttttgaagg tcataaacaa agaccataat tgatgataga cctaatacat     2100

ttcctctgtg tgtgtgtgta acattccaaa tacttttttt ttcttttcca ctgtttgtaa     2160

ggtgcaacaa tttaatattt ttaagggact ttttaagagt tccttaagaa ccaatttaaa     2220

attacttcag tgcaatccta cacagtatca acattagaat tttgatatta gtcttatgtt     2280

atcttccatt ctatttttat ctgctttttg ctgctagttt caaactgcca gtatttttcc     2340

ttttgctttt aaaatagtta caatattttt catgatagcc acagtattgc cacagtttat     2400

tataataaag ggtttttatt tgatttagcg cattcaaagc ttttttctat cacttttgtg     2460

ttcagaatat aacctttgtg tgcgtgtatg ttgtgtgtgt gcatgtgtgg cgtatatgtg     2520

tgttacaggt taatgccttc ttggaattgt gttaatgttc tcttggttta ttatgccatc     2580

agaatggtaa atgagaacac tacaactgta gtcagctcac aatttttaaa taaaggatac     2640

cacagtgcat gctgtttgtt caaaaaaaaa aaaaaaaaa                            2679


<210>  905
<211>  7645
<212>  DNA
<213>  homo sapiens

<400>  905
ggcgctgagc gagctcggag cccgcgctgt gcgcctgcgg ccggggcgcc ccgccgagcg       60

ccggtgcccc ggctcccggg ccgccttcgc cgcgcgggaa ggattcttca aaattaacag      120

aaaccaattc gggccagctg aagagaaaaa ataaaggtgg ctcccggctg cctctgctgc      180

agttcagagc aacttcagga gcttcccagc cgagagcttc aggacgcctt tcctgtccca      240

ctggcccagt tgccacaaca aacaacagag aagacggtga ccatggggga tgtgaagctg      300

gttgcctcgt cacacatttc caaaacctcc ctcagtgtgg atccctcaag agttgactcc      360

atgcccctga cagaggcccc tgctttcatt ttgccccctc ggaacctctg catcaaagaa      420

ggagccaccg ccaagttcga agggcgggtc cggggttacc cagagcccca ggtgacatgg      480

cacagaaacg ggcaacccat caccagcggg ggccgcttcc tgctggattg cggcatccgg      540

gggactttca gccttgtgat tcatgctgtc catgaggagg acaggggaaa gtatacctgt      600

gaagccacca atggcagtgg tgctcgccag gtgacagtgg agttgacagt agaaggaagt      660

tttgcgaagc agcttggtca gcctgttgtt tccaaaacct taggggatag attttcagct      720

ccagcagtgg agacccgtcc tagcatctgg ggggagtgcc caccaaagtt tgctaccaag      780

ctgggccgag ttgtggtcaa agaaggacag atgggacgat tctcctgcaa gatcactggc      840

cggccccaac cgcaggtcac ctggctcaag ggaaatgttc cactgcagcc gagtgcccgt      900

gtgtctgtgt ctgagaagaa cggcatgcag gttctggaaa tccatggagt caaccaagat      960

gacgtgggag tgtacacgtg cctggtggtg aacgggtcgg ggaaggcctc gatgtcagct     1020

gaactttcca tccaaggttt ggacagtgcc aataggtcat ttgtgagaga aacaaaagcc     1080

accaattcag atgtcaggaa agaggtgacc aatgtaatct caaaggagtc gaagctggac     1140

agtctggagg ctgcagccaa aagcaagaac tgctccagcc cccagagagg tggctcccca     1200

ccctgggctg caaacagcca gcctcagccc ccaagggagt ccaagctgga gtcatgcaag     1260

gactcgccca gaacggcccc gcagaccccg gtccttcaga agacttccag ctccatcacc     1320

ctgcaggccg caagagttca gccggaacca agagcaccag gcctgggggt cctatcacct     1380

tctggagaag agaggaagag gccagctcct ccccgtccag ccaccttccc caccaggcag     1440

cctggcctgg ggagccaaga tgttgtgagc aaggctgcta acaggagaat ccccatggag     1500

ggccagaggg attcagcatt ccccaaattt gagagcaagc cccaaagcca ggaggtcaag     1560

gaaaatcaaa ctgtcaagtt cagatgtgaa gggcttgccg tgatggaggt ggccccctcc     1620

ttctccagtg tcctgaagga ctgcgctgtt attgagggcc aggattttgt gctgcagtgc     1680

tccgtacggg ggaccccagt gccccggatc acttggctgc tgaatgggca gcccatccag     1740

tacgctcgct ccacctgcga ggccggcgtg gctgagctcc acatccagga tgccctgccg     1800

gaggaccatg gcacctacac ctgcctagct gagaatgcct tggggcaggt gtcctgcagc     1860

gcctgggtca ccgtccatga aaagaagagt agcaggaaga gtgagtacct tctgcctgtg     1920

gctcccagca agcccactgc acccatcttc ctgcagggcc tctctgatct caaagtcatg     1980

gatggaagcc aggtcactat gactgtccaa gtgtcaggga atccaccccc tgaagtcatc     2040

tggctgcaca atgggaatga gatccaagag tcagaggact tccactttga acagagagga     2100

actcagcaca gcctttgtat ccaggaagtg ttcccggagg acacgggcac gtacacctgc     2160

gaggcctgga acagcgctgg agaggtccgc acccaggccg tgctcacggt acaagagcct     2220

cacgatggca cccagccctg gttcatcagt aagcctcgct cagtgacagc ctccctgggc     2280

cagagtgtcc tcatctcctg cgccatagct ggtgacccct ttcctaccgt gcactggctc     2340

agagatggca aagccctctg caaagacact ggccacttcg aggtgcttca gaatgaggac     2400

gtgttcaccc tggttctaaa gaaggtgcag ccctggcatg ccggccagta tgagatcctg     2460

ctcaagaacc gggttggcga atgcagttgc caggtgtcac tgatgctaca gaacagctct     2520

gccagagccc ttccacgggg gagggagcct gccagctgcg aggacctctg tggtggagga     2580

gttggtgctg atggtggtgg tagtgaccgc tatgggtccc tgaggcctgg ctggccagca     2640

agagggcagg gttggctaga ggaggaagac ggcgaggacg tgcgaggggt gctgaagagg     2700

cgcgtggaga cgaggcagca cactgaggag gcgatccgcc agcaggaggt ggagcagctg     2760

gacttccgag acctcctggg gaagaaggtg agtacaaaga ccctatcgga agacgacctg     2820

aaggagatcc cagccgagca gatggatttc cgtgccaacc tgcagcggca agtgaagcca     2880

aagactgtgt ctgaggaaga gaggaaggtg cacagccccc agcaggtcga ttttcgctct     2940

gtcctggcca agaaggggac ttccaagacc cccgtgcctg agaaggtgcc accgccaaaa     3000

cctgccaccc cggattttcg ctcagtgctg ggtggcaaga agaaattacc agcagagaat     3060

ggcagcagca gtgccgagac cctgaatgcc aaggcagtgg agagttccaa gcccctgagc     3120

aatgcacagc cttcagggcc cttgaaaccc gtgggcaacg ccaagcctgc tgagaccctg     3180

aagccaatgg gcaacgccaa gcctgccgag accctgaagc ccatgggcaa tgccaagcct     3240

gatgagaacc tgaaatccgc tagcaaagaa gaactcaaga aagacgttaa gaatgatgtg     3300

aactgcaaga gaggccatgc agggaccaca gataatgaaa agagatcaga gagccagggg     3360

acagccccag ccttcaagca gaagctgcaa gatgttcatg tggcagaggg caagaagctg     3420

ctgctccagt gccaggtgtc ttctgacccc ccagccacca tcatctggac gctgaacgga     3480

aagaccctca agaccaccaa gttcatcatc ctctcccagg aaggctcact ctgctccgtc     3540

tccatcgaga aggcactgcc tgaggacaga ggcttataca agtgtgtagc caagaatgac     3600

gctggccagg cggagtgctc ctgccaagtc accgtggatg atgctccagc cagtgagaac     3660

accaaggccc cagagatgaa atcccggagg cccaagagct ctcttcctcc cgtgctagga     3720

actgagagtg atgcgactgt gaaaaagaaa cctgccccca agacacctcc gaaggcagca     3780

atgccccctc agatcatcca gttccctgag gaccagaagg tacgcgcagg agagtcagtg     3840

gagctgtttg gcaaagtgac aggcactcag cccatcacct gtacctggat gaagttccga     3900

aagcagatcc aggaaagcga gcacatgaag gtggagaaca gcgagaatgg cagcaagctc     3960

accatcctgg ccgcgcgcca ggagcactgc ggctgctaca cactgctggt ggagaacaag     4020

ctgggcagca ggcaggccca ggtcaacctc actgtcgtgg ataagccaga ccccccagct     4080

ggcacacctt gtgcctctga cattcggagc tcctcactga ccctgtcctg gtatggctcc     4140

tcatatgatg ggggcagtgc tgtacagtcc tacagcatcg agatctggga ctcagccaac     4200

aagacgtgga aggaactagc cacatgccgc agcacctctt tcaacgtcca ggacctgctg     4260

cctgaccacg aatataagtt ccgtgtacgt gcaatcaacg tgtatggaac cagtgagcca     4320

agccaggagt ctgaactcac aacggtagga gagaaacctg aagagccgaa ggatgaagtg     4380

gaggtgtcag atgatgatga gaaggagccc gaggttgatt accggacagt gacaatcaat     4440

actgaacaaa aagtatctga cttctacgac attgaggaga gattaggatc tgggaaattt     4500

ggacaggtct ttcgacttgt agaaaagaaa actcgaaaag tctgggcagg gaagttcttc     4560

aaggcatatt cagcaaaaga gaaagagaat atccggcagg agattagcat catgaactgc     4620

ctccaccacc ctaagctggt ccagtgtgtg gatgcctttg aagaaaaggc caacatcgtc     4680

atggtcctgg agatcgtgtc aggaggggag ctgtttgagc gcatcattga cgaggacttt     4740

gagctgacgg agcgtgagtg catcaagtac atgcggcaga tctcggaggg agtggagtac     4800

atccacaagc agggcatcgt gcacctggac ctcaagccgg agaacatcat gtgtgtcaac     4860

aagacgggca ccaggatcaa gctcatcgac tttggtctgg ccaggaggct ggagaatgcg     4920

gggtctctga aggtcctctt tggcacccca gaatttgtgg ctcctgaagt gatcaactat     4980

gagcccatcg gctacgccac agacatgtgg agcatcgggg tcatctgcta catcctagtc     5040

agtggccttt cccccttcat gggagacaac gataacgaaa ccttggccaa cgttacctca     5100

gccacctggg acttcgacga cgaggcattc gatgagatct ccgacgatgc caaggatttc     5160

atcagcaatc tgctgaagaa agatatgaaa aaccgcctgg actgcacgca gtgccttcag     5220

catccatggc taatgaaaga taccaagaac atggaggcca agaaactctc caaggaccgg     5280

atgaagaagt acatggcaag aaggaaatgg cagaaaacgg gcaatgctgt gagagccatt     5340

ggaagactgt cctctatggc aatgatctca gggctcagtg gcaggaaatc ctcaacaggg     5400

tcaccaacca gcccgctcaa tgcagaaaaa ctagaatctg aagaagatgt gtcccaagct     5460

ttccttgagg ctgttgctga ggaaaagcct catgtaaaac cctatttctc taagaccatt     5520

cgcgatttag aagttgtgga gggaagtgct gctagatttg actgcaagat tgaaggatac     5580

ccagaccccg aggttgtctg gttcaaagat gaccagtcaa tcagggagtc ccgccacttc     5640

cagatagact acgatgagga cgggaactgc tctttaatta ttagtgatgt ttgcggggat     5700

gacgatgcca agtacacctg caaggctgtc aacagtcttg gagaagccac ctgcacagca     5760

gagctcattg tggaaacgat ggaggaaggt gaaggggaag gggaagagga agaagagtga     5820

aacaaagcca gagaaaagca gtttctaagt catattaaaa ggactatttc tctaaaactc     5880

aaaaaaaaaa aaaaaactca agatagtaaa agcacctagt gtgatagatt atcggttagg     5940

tcatttgtgg gttgattctt cagaaacagc agttgatacc tagcagcgtt attgatgggc     6000

attaatctat gttagttggc accttaagat actagtgcag ctagatttca tttagggaaa     6060

tcaccagtaa cttgactgac caattgattt tagagagaaa gtaaccaaac caaatattta     6120

tctgggcaaa gtcataaatt ctccacttga atgcgctcat gaaaaataag gccaaaacaa     6180

gagttctggg ccacagctca gcccagaggg ttcctgggga tgggaggcct ctctctcccc     6240

accccctgac tctagagaac tgggttttct cccagtactc cagcaattca tttctgaaag     6300

cagttgagcc actttattcc aaagtacact gcagatgttc aaactctcca tttctctttc     6360

cccttccacc tgccagtttt gctgactctc aacttgtcat gagtgtaagc attaaggaca     6420

ttatgcttct tcgattctga agacaggtcc ctgctcatgg atgactctgg cttccttagg     6480

aaaatatttt tcttccaaaa tcagtaggaa atctaaactt atcccctctt tgcagatgtc     6540

tagcagcttc agacatttgg ttaagaaccc atgggaaaaa aaaaatcctt gctaatgtgg     6600

tttcctttgt aaaccaggat tcttatttgt gctgttatag aatatcagct ctgaacgtgt     6660

ggtaaagatt tttgtgtttg aatataggag aaatcagttt gctgaaaagt tagtcttaat     6720

tatctattgg ccacgatgaa acagatttca actgataaag agctggagaa ctccatgtac     6780

tttggaatct cctccaagat agccagagtt taatacatct tcattctcaa cactctccaa     6840

agaacttgac ctaccttatg ggttccatat ttttcttctt aaatgtgcat caatcatgcc     6900

ttgcccccaa cctttaaata tattcttaga cctggtaaat gcactcagac ttgcgtcttt     6960

aggaattttt aactttcttt cactacattg gcacttaaat tttttcttta taaagctttt     7020

tgaaggtcat aaacaaagac cataattgat gatagaccta atacatttcc tctgtgtgtg     7080

tgtgtaacat tccaaatact ttttttttct tttccactgt ttgtaaggtg caacaattta     7140

atatttttaa gggacttttt aagagttcct taagaaccaa tttaaaatta cttcagtgca     7200

atcctacaca gtatcaacat tagaattttg atattagtct tatgttatct tccattctat     7260

ttttatctgc tttttgctgc tagtttcaaa ctgccagtat ttttcctttt gcttttaaaa     7320

tagttacaat atttttcatg atagccacag tattgccaca gtttattata ataaagggtt     7380

tttatttgat ttagcgcatt caaagctttt ttctatcact tttgtgttca gaatataacc     7440

tttgtgtgcg tgtatgttgt gtgtgtgcat gtgtggcgta tatgtgtgtt acaggttaat     7500

gccttcttgg aattgtgtta atgttctctt ggtttattat gccatcagaa tggtaaatga     7560

gaacactaca actgtagtca gctcacaatt tttaaataaa ggataccaca gtgcatgctg     7620

tttgttcaaa aaaaaaaaaa aaaaa                                           7645


<210>  906
<211>  3617
<212>  DNA
<213>  homo sapiens

<400>  906
gaagttcggc aggagccaat cccggggctg gtccgggaga aatctcggcg aagggccccg       60

aatagccggg agattacggg gcggggacga gctgtcgcgc tggttgctcg tgcaggagcg      120

ggacccggaa cagaccgccg tgagagagga ggggtgccgg ccgggattcg cggcccggag      180

ctcgggaccg gagtcaggaa tggagagaag ggtaatggtt ttacctctta ttgtggaaac      240

ctgttgagat cacagagaat atactgacgg cataaaaggg cagaaccata gcagggtgcg      300

gttgcttcat tccagcctcg cagtcacctc tgtgccctgc tggttgtctt cccagcgctg      360

ctgtagttgc cttccatgga tctataggag agcaagtcct ccaggagctg gtggtgtctg      420

tcgattgact gagtgctgga gctggcagcc ctgtgcaggc tgccaccttt gcccctttac      480

tgtgcttgct cctgactcta tgtcgcgtct ccaaggagaa gaagtcctca ccagtgaacg      540

gagacctctc tgaactaagg ataccatggc cacgtcagcc ccactacgga gcctggaaga      600

ggaggtgacc tgctccatct gtcttgatta cctgcgggac cctgtgacca ttgactgtgg      660

ccacgtcttc tgccgcagct gcaccacaga cgtccgcccc atctcaggga gccgccccgt      720

ctgcccactc tgcaagaagc cttttaagaa ggagaacatc cgacccgtgt ggcaactggc      780

cagcctggtg gagaacattg agcggctgaa ggtggacaag ggcaggcagc cgggagaggt      840

gacccgggag cagcaggatg caaagttgtg cgagcgacac cgagagaagc tgcactacta      900

ctgtgaggac gacgggaagc tgctgtgcgt gatgtgccgg gagtcccggg agcacaggcc      960

ccacacggcc gtcctcatgg agaaggccgc ccagccccac agggaaaaaa tcctgaacca     1020

cctgagtacc ctaaggaggg acagagacaa aattcagggc ttccaggcaa agggagaagc     1080

tgatatcctg gccgcgctga agaagctcca ggaccagagg cagtacattg tggctgagtt     1140

tgagcagggt catcagttcc tgagggagcg ggaggaacac ctgctggaac agctggcgaa     1200

gctggagcag gagctcacgg agggcaggga gaagttcaag agccggggcg tcggggagct     1260

tgcccggctg gccctggtca tctccgaact ggagggcaag gcgcagcagc cagctgcaga     1320

gctcatgcag gacacgagag acttcctaaa caggtatcca cggaagaagt tctgggttgg     1380

gaaacccatt gctcgagtgg ttaaaaaaaa gaccggagaa ttctcagata aactcctctc     1440

tctgcaacga ggcctgaggg aattccaggg gaagctgctg agagacttgg aatataagac     1500

agtgagcgtc accctggacc cacagtcggc cagtgggtac ctgcagctgt cagaggactg     1560

gaagtgcgtg acctacacca gcctgtacaa gagtgcctac ctgcaccccc agcagtttga     1620

ctgtgagcct ggggtgctag gcagcaaggg cttcacctgg ggcaaggtct actgggaagt     1680

ggaagtggag agggagggct ggtctgagga tgaagaagag ggggatgagg aggaagaggg     1740

agaagaggag gaggaggaag aggaggccgg ctatggggat ggatatgacg actgggaaac     1800

ggacgaagat gaggaatcgt tgggcgatga agaggaagaa gaggaggagg aagaggagga     1860

agttctggaa agctgcatgg tgggggtggc tagagactct gtgaagagga agggagacct     1920

ctccctgcgg ccagaggatg gcgtgtgggc gctgcgcctc tcctcctccg gcatctgggc     1980

caacaccagc cccgaggctg agcttttccc agcactgcgg ccccggagag tgggcatcgc     2040

cctggattat gaagggggca ccgtgacttt caccaacgca gagtcacagg aactcatcta     2100

caccttcact gccaccttca cccggcgcct ggtccccttc ctgtggctca agtggccagg     2160

aacacgcctc ctgctaagac cctgagccct gacatctgcc cccagcccca accctcagat     2220

gcttcacttc tttggaattc caggactctc aatgggggga cgggatgcct ggcctaagca     2280

cctggagcag gggaccccat atccactggt agccacctcc ccattgctgt ggccccctga     2340

aatctcactc agtgctgttg ctccatctac tgccctaatg gggctctttt cccacctcct     2400

gctggtttcc cgagggaact tctgaccctg gagtccatga gggctccttt cctttttgac     2460

cacgaccttg gccccagctc tgcactctct ggaataaggg cccgatgcag cattttcttg     2520

cccagtgtgg caagacctca gaaaaaccag tcaattacgc ctaagatcat tttgctgtcc     2580

ttaaaccccc caggttcctt cttgcacaaa tccactctgc tgcccacctt ccctggcatt     2640

ttaaacagac ctaccccacc ccaactcaga gttaagcata catggcaatg ctgaaaataa     2700

acaaaatcca ctgaggcttc ccaggccatt taaagcctgg agtaccagcg catatcatct     2760

catggggtcc agagtggagt ccaggcttct ctgaaaccag ggctgagcat atttccatag     2820

ccaaggaggt gggactccct ggagctatct gtggtcttag ggaaggatcc agacatacac     2880

ggctttgggg tacaagctgt gatcactgat caataaatta tctctagatt ggtccttgtg     2940

aggggagttt taagaatcca gaacatcttg ctcttgatca gcacatccaa aaacaccaag     3000

acaaacatcc agtggagcag aacctctcct gcctcgggag ttctgaccgg gttccccagc     3060

agggtgttaa gcctctgtct ctggccctac cagcatccag gttccacttt cctaggagag     3120

agtggagatg ggaagacagg gaaaggaagg cagcaggagg ccacaagccc accaggtctt     3180

catgtcaaga gagggagtaa catgtcttct cattgcccac ggacccaacc tctgtccagg     3240

tgcccctcat catcacagtt taacacaagc tcccctgctc cagccaaatt gatctcccag     3300

tcttgtcctt acccattcca agtgctctgc cagcccctgt tcatccaagt tttaagtcct     3360

ccaccctgtt ctaagagact gttccaacgg ctctgggcct cagtggtcac ttgaccacca     3420

ttgtctcaga gctgcccact ttgtgtgtgt cacatgctgc ctgagtcaca tgtacatctt     3480

atttctgcct ctagttttgt aagctcctgg agggcggata acatcttata ctactcttgt     3540

attctcatgg cacctagtgc agtgctgggc acagagtagg tgctcaataa agacttgttg     3600

aatgaaaaaa aaaaaaa                                                    3617


<210>  907
<211>  2989
<212>  DNA
<213>  homo sapiens

<400>  907
ggcgcgcggg cgagcggttg tgcttgtgct tgtggcgcgt ggtgcgggtt tcggcggcgg       60

ctgaggaaga agcgcgggcg gcgccttcgg gaggcgagca ggcagcagtt ggccgtgccg      120

tagcagcgtc ccgcgcgcgg cgggcagcgg cccaggaggc gcgtggcggc gctcggcctc      180

gcggcggcgg cggcggcagc ggcccagcag ttggcggcga gcgcgtctgc gcctgcgcgg      240

cgggccccgc gcccctcctc cccccctggg cgcccccggc ggcgtgtgaa tggcggcctc      300

cgcggcggca gcctcggcag cagcggcctc ggccgcctct ggcagcccgg gcccgggcga      360

gggctccgct ggcggcgaaa agcgctccac cgccccttcg gccgcagcct cggcctctgc      420

ctcagccgcg gcgtcgtcgc ccgcgggggg cggcgccgag gcgctggagc tgctggagca      480

ctgcggcgtg tgcagagagc gcctgcgacc cgagagggag ccccgcctgc tgccctgttt      540

gcactcggcc tgtagtgcct gcttagggcc cgcggccccc gccgccgcca acagctcggg      600

ggacggcggg gcggcgggcg acggcaccgt ggtggactgt cccgtgtgca agcaacagtg      660

cttctccaaa gacatcgtgg agaattattt catgcgtgat agtggcagca aggctgccac      720

cgacgcccag gatgcgaacc agtgctgcac tagctgtgag gataatgccc cagccaccag      780

ctactgtgtg gagtgctcgg agcctctgtg tgagacctgt gtagaggcgc accagcgggt      840

gaagtacacc aaggaccata ctgtgcgctc tactgggcca gccaagtctc gggatggtga      900

acgtactgtc tattgcaacg tacacaagca tgaacccctt gtgctgtttt gtgagagctg      960

tgatactctc acctgccgag actgccagct caatgcccac aaggaccacc agtaccagtt     1020

cttagaggat gcagtgagga accagcgcaa gctcctggcc tcactggtga agcgccttgg     1080

ggacaaacat gcaacattgc agaagagcac caaggaggtt cgcagctcaa tccgccaggt     1140

gtctgacgta cagaagcgtg tgcaagtgga tgtcaagatg gccatcctgc agatcatgaa     1200

ggagctgaat aagcggggcc gtgtgctggt caatgatgcc cagaaggtga ctgaggggca     1260

gcaggagcgc ctggagcggc agcactggac catgaccaag atccagaagc accaggagca     1320

cattctgcgc tttgcctctt gggctctgga gagtgacaac aacacagccc ttttgctttc     1380

taagaagttg atctacttcc agctgcaccg ggccctcaag atgattgtgg atcccgtgga     1440

gccacatggc gagatgaagt ttcagtggga cctcaatgcc tggaccaaga gtgccgaggc     1500

ctttggcaag attgtggcag agcgtcctgg cactaactca acaggccctg cacccatggc     1560

ccctccaaga gccccagggc ccctgagcaa gcagggctct ggcagcagcc agcccatgga     1620

ggtgcaggaa ggctatggct ttgggtcagg agatgatccc tactcaagtg cagagcccca     1680

tgtgtcaggt gtgaaacggt cccgctcagg tgagggcgag gtgagcggcc ttatgcgcaa     1740

ggtgccacga gtgagccttg aacgcctgga cctggacctc acagctgaca gccagccacc     1800

cgtcttcaag gtcttcccag gcagtaccac tgaggactac aaccttattg ttattgaacg     1860

tggcgctgcc gctgcagcta ccggccagcc agggactgcg cctgcaggaa cccctggtgc     1920

cccacccctg gctggcatgg ccattgtcaa ggaggaggag acggaggctg ccattggagc     1980

ccctcctact gccactgagg gccctgagac caaacctgtg cttatggctc ttgcggaggg     2040

tcctggtgct gagggtcccc gcctggcctc acctagtggc agcaccagct cagggctgga     2100

ggtggtggct cctgagggta cctcagcccc aggtggtggc ccgggaaccc tggatgacag     2160

tgccaccatt tgccgtgtct gccagaagcc aggcgatctg gttatgtgca accagtgtga     2220

gttttgtttc cacctggact gtcacctgcc ggccctgcag gatgtaccag gggaggagtg     2280

gagctgctca ctctgccatg tgctccctga cctgaaggag gaggatggca gcctcagcct     2340

ggatggtgca gacagcactg gcgtggtggc caagctctca ccagccaacc agcggaaatg     2400

tgagcgtgta ctgctggccc tattctgtca cgaaccctgc cgccccctgc atcagctggc     2460

taccgactcc accttctccc tggaccagcc cggtggcacc ctggatctga ccctgatccg     2520

tgcccgcctc caggagaagt tgtcacctcc ctacagctcc ccacaggagt ttgcccagga     2580

tgtgggccgc atgttcaagc aattcaacaa gttaactgag gacaaggcag acgtgcagtc     2640

catcatcggc ctgcagcgct tcttcgagac gcgcatgaac gaggccttcg gtgacaccaa     2700

gttctctgct gtgctggtgg agcccccgcc gatgagcctg cctggtgctg gcctgagttc     2760

ccaggagctg tctggtggcc ctggtgatgg cccctgaggc tggagccccc atggccagcc     2820

cagcctggct ctgttctctg tcctgtcacc ccatccccac tcccctggtg gcctgactcc     2880

cactccctgg tggccccatc ccccagttcc tcacgatatg gtttttactt ctgtggattt     2940

aataaaaact tcaccagtta aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                 2989


<210>  908
<211>  2989
<212>  DNA
<213>  homo sapiens

<400>  908
ggcgcgcggg cgagcggttg tgcttgtgct tgtggcgcgt ggtgcgggtt tcggcggcgg       60

ctgaggaaga agcgcgggcg gcgccttcgg gaggcgagca ggcagcagtt ggccgtgccg      120

tagcagcgtc ccgcgcgcgg cgggcagcgg cccaggaggc gcgtggcggc gctcggcctc      180

gcggcggcgg cggcggcagc ggcccagcag ttggcggcga gcgcgtctgc gcctgcgcgg      240

cgggccccgc gcccctcctc cccccctggg cgcccccggc ggcgtgtgaa tggcggcctc      300

cgcggcggca gcctcggcag cagcggcctc ggccgcctct ggcagcccgg gcccgggcga      360

gggctccgct ggcggcgaaa agcgctccac cgccccttcg gccgcagcct cggcctctgc      420

ctcagccgcg gcgtcgtcgc ccgcgggggg cggcgccgag gcgctggagc tgctggagca      480

ctgcggcgtg tgcagagagc gcctgcgacc cgagagggag ccccgcctgc tgccctgttt      540

gcactcggcc tgtagtgcct gcttagggcc cgcggccccc gccgccgcca acagctcggg      600

ggacggcggg gcggcgggcg acggcaccgt ggtggactgt cccgtgtgca agcaacagtg      660

cttctccaaa gacatcgtgg agaattattt catgcgtgat agtggcagca aggctgccac      720

cgacgcccag gatgcgaacc agtgctgcac tagctgtgag gataatgccc cagccaccag      780

ctactgtgtg gagtgctcgg agcctctgtg tgagacctgt gtagaggcgc accagcgggt      840

gaagtacacc aaggaccata ctgtgcgctc tactgggcca gccaagtctc gggatggtga      900

acgtactgtc tattgcaacg tacacaagca tgaacccctt gtgctgtttt gtgagagctg      960

tgatactctc acctgccgag actgccagct caatgcccac aaggaccacc agtaccagtt     1020

cttagaggat gcagtgagga accagcgcaa gctcctggcc tcactggtga agcgccttgg     1080

ggacaaacat gcaacattgc agaagagcac caaggaggtt cgcagctcaa tccgccaggt     1140

gtctgacgta cagaagcgtg tgcaagtgga tgtcaagatg gccatcctgc agatcatgaa     1200

ggagctgaat aagcggggcc gtgtgctggt caatgatgcc cagaaggtga ctgaggggca     1260

gcaggagcgc ctggagcggc agcactggac catgaccaag atccagaagc accaggagca     1320

cattctgcgc tttgcctctt gggctctgga gagtgacaac aacacagccc ttttgctttc     1380

taagaagttg atctacttcc agctgcaccg ggccctcaag atgattgtgg atcccgtgga     1440

gccacatggc gagatgaagt ttcagtggga cctcaatgcc tggaccaaga gtgccgaggc     1500

ctttggcaag attgtggcag agcgtcctgg cactaactca acaggccctg cacccatggc     1560

ccctccaaga gccccagggc ccctgagcaa gcagggctct ggcagcagcc agcccatgga     1620

ggtgcaggaa ggctatggct ttgggtcagg agatgatccc tactcaagtg cagagcccca     1680

tgtgtcaggt gtgaaacggt cccgctcagg tgagggcgag gtgagcggcc ttatgcgcaa     1740

ggtgccacga gtgagccttg aacgcctgga cctggacctc acagctgaca gccagccacc     1800

cgtcttcaag gtcttcccag gcagtaccac tgaggactac aaccttattg ttattgaacg     1860

tggcgctgcc gctgcagcta ccggccagcc agggactgcg cctgcaggaa cccctggtgc     1920

cccacccctg gctggcatgg ccattgtcaa ggaggaggag acggaggctg ccattggagc     1980

ccctcctact gccactgagg gccctgagac caaacctgtg cttatggctc ttgcggaggg     2040

tcctggtgct gagggtcccc gcctggcctc acctagtggc agcaccagct cagggctgga     2100

ggtggtggct cctgagggta cctcagcccc aggtggtggc ccgggaaccc tggatgacag     2160

tgccaccatt tgccgtgtct gccagaagcc aggcgatctg gttatgtgca accagtgtga     2220

gttttgtttc cacctggact gtcacctgcc ggccctgcag gatgtaccag gggaggagtg     2280

gagctgctca ctctgccatg tgctccctga cctgaaggag gaggatggca gcctcagcct     2340

ggatggtgca gacagcactg gcgtggtggc caagctctca ccagccaacc agcggaaatg     2400

tgagcgtgta ctgctggccc tattctgtca cgaaccctgc cgccccctgc atcagctggc     2460

taccgactcc accttctccc tggaccagcc cggtggcacc ctggatctga ccctgatccg     2520

tgcccgcctc caggagaagt tgtcacctcc ctacagctcc ccacaggagt ttgcccagga     2580

tgtgggccgc atgttcaagc aattcaacaa gttaactgag gacaaggcag acgtgcagtc     2640

catcatcggc ctgcagcgct tcttcgagac gcgcatgaac gaggccttcg gtgacaccaa     2700

gttctctgct gtgctggtgg agcccccgcc gatgagcctg cctggtgctg gcctgagttc     2760

ccaggagctg tctggtggcc ctggtgatgg cccctgaggc tggagccccc atggccagcc     2820

cagcctggct ctgttctctg tcctgtcacc ccatccccac tcccctggtg gcctgactcc     2880

cactccctgg tggccccatc ccccagttcc tcacgatatg gtttttactt ctgtggattt     2940

aataaaaact tcaccagtta aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                 2989


<210>  909
<211>  3684
<212>  DNA
<213>  homo sapiens

<400>  909
ccgcggaccc accccctcgc ttccggcatc ggctgtgggg agtaccggct gcagtcggct       60

gtgccgggag ggtaggatgg cgtctggccg atgcggtgat agcaccgaaa gcagacggcc      120

gccaggcgct ccccctaccc cccgaagttt ctccccagcg gcgggggatg ggggtaggcg      180

gttcctctgt tctttctgcg ttccccgcgg cctcttacca cagagacgcg ggcctccacc      240

gtcctagccc tcccgccctg ttctctagtg cggactagag cgtctcctcg ccatttcctg      300

tcgccctggg gccccgcggg gaaaaagggg gagtagcagg acagcggagg gaagtcgcga      360

gcttaggtgg tgtgtagacg ccggaagtgt tgggaaggag gccggaagct aggggcgggg      420

ccaggaagtg aggaggggcg ggggtttatg aggagtccaa gggagcattg gggcagactt      480

gtactcagag ccacctgagg gacttggcgg tggcgcccag cactgtcccc tcccctcgta      540

gagacacggt tgtcgtttgg gagtagggaa cactgtgttg gggtgggttg tcggcaggac      600

atctctctgg ctgctcttgg ggcgaggtgt ggaggggcag ggctgggggt ggagccgggt      660

cgccagggcg tcggtaggga agacccccgc ccctcgcccc cccaccgaac ctctacactg      720

gctggctgga cactaagatg gctgccgttg ccatgacacc caaccctgtg cagacccttc      780

aggaggaggc ggtgtgcgcc atctgcctcg attacttcac ggaccccgtg tccatcggct      840

gcgggcacaa cttctgccga gtttgtgtaa cccagttgtg gggtggggag gatgaggagg      900

acagagatga gttagatcgg gaggaggagg aggaggacgg agaggaggag gaagtggagg      960

ctgtgggggc tggcgcgggg tgggacaccc ccatgcggga tgaagactac gagggtgaca     1020

tggaggagga ggtcgaggag gaagaagagg gtgtgttctg gaccagtggc atgagcaggt     1080

ccagctggga caacatggac tatgtgtggg aggaggagga cgaggaggaa gacctggact     1140

actacttggg ggacatggag gaggaggacc tgagggggga ggatgaggag gacgaggagg     1200

aagtgctgga ggaggttgag gaagaggatc tagaccccgt caccccactg cccccgcctc     1260

cagcccctcg gaggtgcttc acatgccctc agtgccgaaa gagctttcct cggcggagct     1320

tccgccccaa cctgcagctg gccaatatgg tccaggtgat tcggcagatg cacccaaccc     1380

ctggtcgagg gagccgcgtg accgatcagg gcatctgtcc caaacaccaa gaagccctga     1440

agctcttctg cgaggtagac gaagaggcca tctgtgtggt gtgccgagaa tccaggagcc     1500

acaaacagca cagcgtggtg ccattggagg aggtggtgca ggagtacaag gccaaactgc     1560

aggggcacgt ggaaccactg aggaagcacc tggaggcagt gcagaagatg aaagccaagg     1620

aggagaggcg agtgacagaa ctgaagagcc agatgaagtc agagctggca gcggtggcct     1680

cggagtttgg gcgactgaca cggtttctgg ctgaagagca ggcagggctg gaacggcgtc     1740

tcagagagat gcatgaagcc cagctggggc gtgcgggagc cgcggctagt cgccttgcag     1800

aacaggccgc ccagctcagc cgcctgctgg cagaggccca ggagcggagc cagcaggggg     1860

gtctccggct gctccaggac atcaaggaga ctttcaatag gtgtgaagag gtacagctgc     1920

agcccccaga ggtctggtcc cctgacccgt gccaacccca tagccatgac ttcctgacag     1980

atgccatcgt gaggaaaatg agccggatgt tctgtcaggc tgcgagagtg gacctgacgc     2040

tggaccctga cacggctcac ccggccctga tgctgtcccc tgaccgccgg ggggtccgcc     2100

tggcagagcg gcggcaggag gttgctgacc atcccaagcg cttctcggcc gactgctgcg     2160

tactgggggc ccagggcttc cgctccggcc ggcactactg ggaggtagag gtgggcgggc     2220

ggcggggctg ggcggtgggt gctgcccgtg aatcaaccca tcataaggaa aaggtgggcc     2280

ctgggggttc ctccgtgggc agcggggatg ccagctcctc gcgccatcac catcgccgcc     2340

gccggctcca cctgccccag cagcccctgc tccagcggga agtgtggtgc gtgggcacca     2400

acggcaaacg ctatcaggcc cagagctcca cagaacagac gctgctgagc cccagtgaga     2460

aaccaaggcg ctttggtgtg tacctggact atgaagctgg gcgcctgggc ttctacaacg     2520

cagagactct agcccacgtg cacaccttct cggctgcctt cctgggcgag cgtgtctttc     2580

ctttcttccg ggtgctctcc aagggcaccc gcatcaagct ctgcccttga ttatcctgcc     2640

acccgcaggg gcccctctgt cagcacttgg ggggtgggtg gtggagggtg gcccgtaagt     2700

ttgagggctc aaaggctctt cccactgctt gttactgtgt tgcttcccac tcccccttga     2760

ccccaggccc ctgcttctcc ctctaggagc ctaaagaacc ctcctggcct ccagctcagc     2820

cttctctcac ctactatgtc tgtccaacag gtctgcatgg gtccctgata atgagaacag     2880

ctgcctggtc ttctctccca gtctgcctag cccagccctg ggactggaat ttgagtaggg     2940

gatgagggga aattgtaatt tcattcctta acttcctttt ccccacccct gctcttcaac     3000

ctctttatca gttctgaggc tggagggttt gggcaaggca acatccccat tccaattcca     3060

ttttctgatg cagattttag ctgagggatt tggaagccat ttggggaggc aggctgggcc     3120

aaagggtaga gctgggtaat aaatgtctat tctcctgggg aggagggatt ctaaactttc     3180

cttccgtcct caatttctac ctccatagac cggccagaat ttagcttcac ttgagagaga     3240

tctggaatgg tcgccatgat tgaaaccacg caccattaca tcatcattac attaattaca     3300

tcaacataaa ttatttcttc ccccttccct tttccagcac tcaaccaagg agcaaagctc     3360

atcccacccc acacccctcc caggtctgct cactgccagg ctcctctccc ctttgttcag     3420

tggagctggc ttttctccca gcccctttcc atgcctttca ctccatttgg caagctctga     3480

gggggagcct ggggacgggt ttgggtcccc aggaggagag ccttgggtat aatctatttt     3540

tctaggagcc tcttgccttg tcacttgcag ctttcgccct ctgctttgat ggctgaggtg     3600

aactcatgtt ctttgggaaa agggaaggcg tgctgtggaa ataaaatgtt tatttgcttc     3660

tctaaaaaaa aaaaaaaaaa aaaa                                            3684


<210>  910
<211>  2744
<212>  DNA
<213>  homo sapiens

<400>  910
ccgcggaccc accccctcgc ttccggcatc ggctgtgggg agtaccggct gcagtcggct       60

gtgccgggag ggtaggatgg cgtctggccg atgcggtgat agcaccgaaa gcagacggcc      120

gccaggcgct ccccctaccc cccgaagttt ctccccagcg gcgggggatg ggggtaggcg      180

gttcctctgt tctttctgcg ttccccgcgg cctcttacca cagagacgcg ggcctccacc      240

gtcctagccc tcccgccctg ttctctagtg cggactagag cgtctcctcg ccatttcctg      300

tcgccctggg gccccgcggg gaaaaagggg gagtagcagg acagcggagg gaagtcgcga      360

gcttaggtgg tgtgtagacg ccggaagtgt tgggaaggag gccggaagct aggggcgggg      420

ccaggaagtg aggaggggcg ggggtttatg aggagtccaa gggagcattg gggcagactt      480

gtactcagag ccacctgagg gacttggcgg tggcgcccag cactgtcccc tcccctcgta      540

gagacacggt tgtcgtttgg gagtagggaa cactgtgttg gggtgggttg tcggcaggac      600

atctctctgg ctgctcttgg ggcgaggtgt ggaggggcag ggctgggggt ggagccgggt      660

cgccagggcg tcggtaggga agacccccgc ccctcgcccc cccaccgaac ctctacactg      720

gctggctgga cactaagatg gctgccgttg ccatgacacc caaccctgtg cagacccttc      780

aggaggaggc ggtgtgcgcc atctgcctcg attacttcac ggaccccgtg tccatcggct      840

gcgggcacaa cttctgccga gtttgtgtaa cccagttgtg gggtggggag gatgaggagg      900

acagagatga gttagatcgg gaggaggagg aggaggacgg agaggaggag gaagtggagg      960

ctgtgggggc tggcgcgggg tgggacaccc ccatgcggga tgaagactac gagggtgaca     1020

tggaggagga ggtcgaggag gaagaagagg gtgtgttctg gaccagtggc atgagcaggt     1080

ccagctggga caacatggac tatgtgtggg aggaggagga cgaggaggaa gacctggact     1140

actacttggg ggacatggag gaggaggacc tgagggggga ggatgaggag gacgaggagg     1200

aagtgctgga ggaggttgag gaagaggatc tagaccccgt caccccactg cccccgcctc     1260

cagcccctcg gaggtgcttc acatgccctc agtgccgaaa gagctttcct cggcggagct     1320

tccgccccaa cctgcagctg gccaatatgg tccaggtgat tcggcagatg cacccaaccc     1380

ctggtcgagg gagccgcgtg accgatcagg gcatctgtcc caaacaccaa gaagccctga     1440

agctcttctg cgaggtagac gaagaggcca tctgtgtggt gtgccgagaa tccaggagcc     1500

acaaacagca cagcgtggtg ccattggagg aggtggtgca ggagtacaag gccaaactgc     1560

aggggcacgt ggaaccactg aggaagcacc tggaggcagt gcagaagatg aaagccaagg     1620

aggagaggcg agtgacagaa ctgaagagcc agatgaagtc agagctggca gcggtggcct     1680

cggagtttgg gcgactgaca cggtttctgg ctgaagagca ggcagggctg gaacggcgtc     1740

tcagagagat gcatgaagcc cagctggggc gtgcgggagc cgcggctagt cgccttgcag     1800

aacaggccgc ccagctcagc cgcctgctgg cagaggccca ggagcggagc cagcaggggg     1860

gtctccggct gctccaggac atcaaggaga ctttcaatag gtgtgaagag gtacagctgc     1920

agcccccaga ggtctggtcc cctgacccgt gccaacccca tagccatgac ttcctgacag     1980

atgccatcgt gaggaaaatg agccggatgt tctgtcaggc tgcgagagtg gacctgacgc     2040

tggaccctga cacggctcac ccggccctga tgctgtcccc tgaccgccgg ggggtccgcc     2100

tggcagagcg gcggcaggag gttgctgacc atcccaagcg cttctcggcc gactgctgcg     2160

tactgggggc ccagggcttc cgctccggcc ggcactactg ggaggagcct aaagaaccct     2220

cctggcctcc agctcagcct tctctcacct actatgtctg tccaacagac cggccagaat     2280

ttagcttcac ttgagagaga tctggaatgg tcgccatgat tgaaaccacg caccattaca     2340

tcatcattac attaattaca tcaacataaa ttatttcttc ccccttccct tttccagcac     2400

tcaaccaagg agcaaagctc atcccacccc acacccctcc caggtctgct cactgccagg     2460

ctcctctccc ctttgttcag tggagctggc ttttctccca gcccctttcc atgcctttca     2520

ctccatttgg caagctctga gggggagcct ggggacgggt ttgggtcccc aggaggagag     2580

ccttgggtat aatctatttt tctaggagcc tcttgccttg tcacttgcag ctttcgccct     2640

ctgctttgat ggctgaggtg aactcatgtt ctttgggaaa agggaaggcg tgctgtggaa     2700

ataaaatgtt tatttgcttc tctaaaaaaa aaaaaaaaaa aaaa                      2744


<210>  911
<211>  4963
<212>  DNA
<213>  homo sapiens

<400>  911
ggcgcgggcg cgggcggggg cggagtggcg gcggcagcgg cggctagaag cggcagccca       60

gagccctctc gcggccgcgg cggcagcagc agcgccagcc ccagcaacac tgaggccgcc      120

gccgccgcct ggcgctcccg ccgcccggcc cgacatgagt gaggcggttc gggtaccctc      180

gcccgccact ccgctggtgg tggcggcggc cgcgcctgag gagaggaaag ggaaggagtc      240

agagcgcgag aagctgccgc ccatcgtatc ggcgggcgcc ggcgcgaccg cgggtttgga      300

cagaggagcc aaaggccaaa tttccacttt cagcagtttt atttcagctg ttagcccgaa      360

gaaagaagct gctgaaaaca gaagttcacc tgcacatctt gttttcccta acatcaagaa      420

tgtgagagaa ccaccaccaa tttgccttga tgttagacaa aaacagcgta catctatgga      480

tgcatcatca tccgaaatga aggccccagt ccttccagaa cctattcttc ctatccagcc      540

caaaactgtg aaagactttc aggaagatgt agaaaaagtt aagtcatcag gagattggaa      600

agcagtacat gatttttatc taacaacgtt tgattctttc ccagaattaa atgctgcatt      660

taagaaagat gccactgcct catttaacac cattgaagac tctgggatta atgctaaatt      720

tgtgaatgct gtgtatgata ccttacttaa tactcctcaa gacgttcaga agacagtatt      780

aaagggaatc attaacagcc tgttacgaga atggaaaggt ccacgaacaa aagatgatct      840

tagagcatat tttatacttt tacagaatcc tcagtttaat aacacatcta cgtatgtcat      900

ctatgctcac ttgctacgac agatagctac cttagtggaa gctgaccatc atttcctagt      960

tcactggttt aaaaaattgt cccagaagag gttcaaacaa ttggtagaga gattgctgca     1020

atttatttct ttacgcctgt ttcctgcaaa gcctgaagaa tttccaccta taacaaagtg     1080

ttcctggtgg attccatcag ccgctaaagt gttggcttta cttaatactg caaacaattt     1140

agttcaccct ccccttattc cttatactga tttctataat tctacattgg atcacattga     1200

tctcatggaa gaatatcata cttggcaaaa ctttggaaac tctcacaggt tttccttctg     1260

tcagtaccca ttcgttattt ctgtagctgc aaaaaaaatc attattcaga gagactcaga     1320

gcaacagatg ataaacatcg caaggcaaag tctggtggat aaagtatctc gaagacagag     1380

acctgatatg aatatattat ttctaaatat gaaagtaaga cggacacatc tggttagcga     1440

ttcacttgat gagctaaccc ggaaaagagc cgatttgaaa aagaagttaa aagttacatt     1500

tgtaggggaa gctggtttgg atatgggtgg tttgactaaa gaatggttcc ttcttctaat     1560

tcgccaaatt tttcatccag attatggcat gtttacatat cacaaggatt cacactgcca     1620

ttggtttagc agctttaaat gtgataacta ttctgaattc cgattggttg gaattcttat     1680

gggactagct gtttataaca gcatcacctt ggatattcgt ttccctccct gctgttacaa     1740

gaaattattg agccctccca tcattcctag tgatcaaaat ataccagtag gcatctgcaa     1800

tgttaccgtg gacgacttat gtcaaattat gcctgagttg gcccatggat taagtgaact     1860

cttatcacat gaaggcaatg ttgaagaaga tttctattca acatttcagg tttttcaaga     1920

agaatttgga ataatcaagt cctataattt aaagcccggt ggtgataaaa tttcagttac     1980

caatcaaaat agaaaagaat atgtacagct ttatactgac ttccttctga acaaatccat     2040

ctataagcag tttgctgcat tttattatgg atttcatagt gtgtgtgctt caaatgccct     2100

aatgctgctt cgtccagaag aggttgaaat tttggtctgt ggaagtcctg acctggatat     2160

gcatgctctg cagagaagta ctcagtatga tggctatgca aaaacggact taactataaa     2220

atacttttgg gatgttgtgc ttggatttcc tcttgatctt caaaagaagt tgctacattt     2280

tactacaggg agtgacagag tacctgtagg agggatggct gatttgaact ttaaaatctc     2340

aaagaatgaa acttctacta actgcttacc tgtggcccat acctgcttca atcaactttg     2400

ccttcccccc tacaagagca aaaaggatct gaaacagaaa ttgatcattg gaatttcaaa     2460

ttcagaaggt tttggacttg agtaacctag aagacttgaa atataatctt ttatatgtag     2520

cattcacttc cctcttactg tgcctttagc cttttcatgt ttctgtctca aaacactttg     2580

acaaagctca ccaactttaa aatattaagt ttttaaaaaa tcaaatatga agtatgttca     2640

gcaaaggcat aattttctaa aaacacacac agaaatcgct tgagtgagga aaagtccaca     2700

tggcagagac aggtatggtc cagttcctct tttatatagc actttatcat tctccacaag     2760

tagtttgtca caggcattcc actgggaaag caaagtacag tgaagaatga atttatggta     2820

tagttgaacc cagtggcaga ttgtacactg ctagcactgc tagcacacag tagcaaagca     2880

aacagctaca ttatctttaa cataaggcat gtagccatat tttcatatag tggtatacaa     2940

cacagtatca ttgcaaatgc agtttacagg gatttttgat atactggctt gggacctata     3000

agattcttct cagcagttgc tgaaaagcat gtaaataact acataatagc ctgagaataa     3060

tgggattttg atagtgccat ttattgttaa agatttattt ttacaaagta aattcagggt     3120

tttagatgtg tacacagctt ttacaaatca ataaagatga ttgtacaaga gtattttcag     3180

actaattgga ttcaaggtta tattctttta agtgttgtta gtctgcatgc acattggcag     3240

taaactagtt acttgtgtac tctgtaatat ttgtataatg atcatttctt cttaaggctc     3300

aagatattag aaaagaaatc agacctaaat aatcattgat gaagtatgtc agttacaagc     3360

acaaaagaat ataactgctt ttataaatct tttgaatcat gtacaagact tatatctaca     3420

ttttttgatc accagttgta ccaaaacact aatttttgaa aaagataggt taaagtattt     3480

gacaaaagtg aatacaataa taacacttgt gtcaaaatga tatagcttag tataaaaata     3540

aaattcaacg ttttggccaa aatgtttgtt tttcactgga ttctgaatat aataaattca     3600

aagtaccctt tttttagagt ttctaataaa gtagtatgta aaaagaaact gcattttaag     3660

tcagacagta aatgtttttt ttaatttaca gcaaatgaag cagttttatt agcatgttac     3720

aaatattgcc aaaccaagac ttctctacca tactttaaca gctttccttc agaaaactct     3780

gaagttatat ttgcaataat aatgaaacca gcatttagta ccagcatatg gttcatatgc     3840

aaataatact ttccccaaaa tctttctggg ctaggctatt ttcttgctat gcttcctgca     3900

cccaaccagc agaattcttc cagggtggag gaactaatca gcttgttctc caacagttct     3960

gaagccaacc cacaaatctt tgaggaaaag gggtcacttt gtttactatt ctcttggaga     4020

tggaagtgat tctgctcttc catttgggta tattatttca agggtatttc ttcttaaaaa     4080

tcttggaaag cctaagagag ttaaaggcat cctggttttg tttcattttg ctctgtttta     4140

aatccatatg caaataaaac tgcttctctc ttacactgct tgaactagaa aatcagcttt     4200

ttaatgtagg ttaccactta taagcacaaa agaaacatgt ataagaaacc agatttaagt     4260

gttttaaata aaatgtaaac agtttttatt tggtagagat gactcatgga aaaattgtgt     4320

tggcttggtc tgcatgttta atgatgtgct tgtatatcga ttagctgtgt cacttttaaa     4380

taagaagtcc acacaagcaa gccaaatttt tagatgacga agtccataaa taactagaga     4440

atttttgtta tctgttgtta agttgaaatg tataatcatt tatcactaaa ttgcacattg     4500

cctttattta tttgtgctct gtttttggtt tacagtgtaa taatacctca tttaaaaaat     4560

aaaaaccact actgttacat tttattaatt taaaaagcta gaaaattcat gtagttactt     4620

tttttacata tataatctgt taatgaatta ttgatttttg tatctgccac agtaaattaa     4680

agcattacac agtatttatc agtatttttt aaacatcctg tcctttttta aaatctttgc     4740

ttagtcagtc atatttttgt ctgtatgatt agaagttttt acgtccttcc ttttttgtac     4800

aaatctgtat tgtattaatt tctggatgca atttttcaaa tattaaaatt atacagtcag     4860

tcaggcttca gtttattttt tgaacacttg ggcaattaat taaagccata tgtttaaaat     4920

attttataaa aaaaaaaaaa aaaaaaagaa aaaaaaaaaa aaa                       4963


<210>  912
<211>  2397
<212>  DNA
<213>  homo sapiens

<400>  912
cacgcgcccc tcctccgcat ctgagcgggg gagcggcggc ccccagctga atgggcgcga       60

gagcggcgct gggggcgggt gggggcgcgg ggtaccgggc tggcggccgg ccggcgcccc      120

ctcattagta tgcggacgaa ggcggcgggc tgcgcggagc ggcgtcccct gcagccgcgg      180

accgaggcag cggcggcacc tgccggccga gcaatgccaa gtgagtacac ctatgtgaaa      240

ctgagaagtg attgctcgag gccttccctg caatggtaca cccgagctca aagcaagatg      300

agaaggccca gcttgttatt aaaagacatc ctcaaatgta cattgcttgt gtttggagtg      360

tggatccttt atatcctcaa gttaaattat actactgaag aatgtgacat gaaaaaaatg      420

cattatgtgg accctgacca tgtaaagaga gctcagaaat atgctcagca agtcttgcag      480

aaggaatgtc gtcccaagtt tgccaagaca tcaatggcgc tgttatttga gcacaggtat      540

agcgtggact tactcccttt tgtgcagaag gcccccaaag acagtgaagc tgagtccaag      600

tacgatcctc cttttgggtt ccggaagttc tccagtaaag tccagaccct cttggaactc      660

ttgccagagc acgacctccc tgaacacttg aaagccaaga cctgtcggcg ctgtgtggtt      720

attggaagcg gaggaatact gcacggatta gaactgggcc acaccctgaa ccagttcgat      780

gttgtgataa ggttaaacag tgcaccagtt gagggatatt cagaacatgt tggaaataaa      840

actactataa ggatgactta tccagagggc gcaccactgt ctgaccttga atattattcc      900

aatgacttat ttgttgctgt tttatttaag agtgttgatt tcaactggct tcaagcaatg      960

gtaaaaaagg aaaccctgcc attctgggta cgactcttct tttggaagca ggtggcagaa     1020

aaaatcccac tgcagccaaa acatttcagg attttgaatc cagttatcat caaagagact     1080

gcctttgaca tccttcagta ctcagagcct cagtcaaggt tctggggccg agataagaac     1140

gtccccacaa tcggtgtcat tgccgttgtc ttagccacac atctgtgcga tgaagtcagt     1200

ttggcgggtt ttggatatga cctcaatcaa cccagaacac ctttgcacta cttcgacagt     1260

caatgcatgg ctgctatgaa ctttcagacc atgcataatg tgacaacgga aaccaagttc     1320

ctcttaaagc tggtcaaaga gggagtggtg aaagatctca gtggaggcat tgatcgtgaa     1380

ttttgaacac agaaaacctc agttgaaaat gcaactctaa ctctgagagc tgtttttgac     1440

agccttcttg atgtatttct ccatcctgca gatactttga agtgcagctc atgtttttaa     1500

cttttaattt aaaaacacaa aaaaaatttt agctcttccc actttttttt tcctatttat     1560

ttgaggtcag tgtttgtttt tgcacaccat tttgtaaatg aaacttaaga attgaattgg     1620

aaagacttct caaagagaat tgtatgtaac gatgttgtat tgatttttaa gaaagtaatt     1680

taatttgtaa aacttctgct cgtttacact gcacattgaa tacaggtaac taattggaag     1740

gagaggggag gtcactcttt tgatggtggc cctgaacctc attctggttc cctgctgcgc     1800

tgcttggtgt gacccacgga ggatccactc ccaggatgac gtgctccgta gctctgctgc     1860

tgatactggg tctgcgatgc agcggcgtga ggcctgggct ggttggagaa ggtcacaacc     1920

cttctctgtt ggtctgcctt ctgctgaaag actcgagaac caaccaggga agctgtcctg     1980

gaggtccctg gtcggagagg gacatagaat ctgtgacctc tgacaactgt gaagccaccc     2040

tgggctacag aaaccacagt cttcccagca attattacaa ttcttgaatt ccttggggat     2100

tttttactgc cctttcaaag cacttaagtg ttagatctaa cgtgttccag tgtctgtctg     2160

aggtgactta aaaaatcaga acaaaacttc tattatccag agtcatggga gagtacaccc     2220

tttccaggaa taatgttttg ggaaacactg aaatgaaatc ttcccagtat tataaattgt     2280

gtatttaaaa aaaagaaact tttctgaatg cctacctggc ggtgtatacc aggcagtgtg     2340

ccagtttaaa aagatgaaaa agaataaaaa cttttgagga acaaaaaaaa aaaaaaa        2397


<210>  913
<211>  3617
<212>  DNA
<213>  homo sapiens

<400>  913
aagtttccaa gtggtcaact tgaccgatgc tttggcaatt gaaaaagggc agaaaggcgc       60

gggctagtgg gtggatgggg acaaagatct aagtcacctt cttccagcgt gtgagcctgg      120

gaggagggtg ggggtcctga ggagcaagag gtacgaggaa ggaaaaggag agggcttctg      180

ggttagtttc cacctcctgc tttccaactc acggcgcttt ccttccggaa aggacgctgg      240

attcagggcg cgccagtacg cgcagtagcg gcccgcgagt cggcaggtgg gtagccccgg      300

cgcgggagga aggggaagtt accttcccct cggaagaggg cgctggctcc cccatcctgc      360

ctttataata aggccaccgg aggagaggaa gcagccagct gccgtctgcg ctttgcaaag      420

catgcagtta ggggagcagc tcttggtgag ctcagtgaac ctgcctggcg cgcacttcta      480

cccgctggag agtgcgcgag gcggcagcgg cgggagcgct ggccacctcc ccagcgcggc      540

cccctctcct cagaagttgg acttagacaa agcgtccaag aagttttccg gcagtctctc      600

ctgcgaggcg gtgagcgggg agcccgcagc cgccagcgca ggggcccccg cggccatgct      660

tagtgacacc gacgccgggg acgcatttgc cagcgctgcg gcagtggcca agccggggcc      720

cccggacggc cgcaagggct ccccctgcgg ggaggaggag ctgccctccg ccgctgcagc      780

cgccgccgcc gccgccgccg cggctgcggc cactgcgcgc tactccatgg acagcctgag      840

ctccgagcgg tactacctcc agtcccccgg tcctcagggg tcggagctgg ctgcgccctg      900

ctcactcttc ccgtaccagg cggcggctgg ggcgccccac ggacctgtgt acccggctcc      960

taacggggcg cgctacccct acggctccat gctgcccccc ggcggcttcc ccgcggctgt     1020

gtgcccaccc gggagggcgc agttcggccc aggagccggt gcgggcagtg gcgcgggcgg     1080

tagcagcggc gggggcggcg gcccgggcac ctatcagtac agccaggggg ctccgctcta     1140

cgggccgtac cctggagccg cagcggcggg atcttgcgga ggactggggg gcctgggggt     1200

tccaggttct ggcttccgtg cccacgtcta cctgtgcaac cggcctctgt ggctcaaatt     1260

ccaccgccac caaactgaga tgatcattac gaaacagggc aggcgcatgt ttcctttctt     1320

gagcttcaac ataaacggac tcaatcccac tgcccactac aatgtgttcg tagaggtggt     1380

gctggcggac cccaaccact ggcgcttcca ggggggcaaa tgggtgacct gtggcaaagc     1440

cgacaataac atgcagggca acaaaatgta tgttcaccca gagtctccta atactggttc     1500

ccactggatg agacaggaga tttcattcgg gaaattaaaa ctcaccaata acaaaggcgc     1560

aaataacaac aacacccaga tgatagtctt acaatcctta cacaaatacc aaccccgact     1620

gcatattgtt gaagttacag aggatggcgt ggaggacttg aatgagccct caaagaccca     1680

gacttttacc ttctcagaaa cgcaattcat tgcagtgact gcctaccaaa acaccgatat     1740

tactcaacta aagattgatc ataacccctt tgcaaaaggc ttcagagaca actatgattc     1800

atcccatcag attgtccctg gaggtcggta cggcgttcaa tccttcttcc cggagccctt     1860

tgtcaacact ttacctcaag cccgctatta taatggcgag agaaccgtgc cacagaccaa     1920

cggcctcctt tcaccccaac agagcgaaga ggtggccaac cctccccagc ggtggcttgt     1980

cacgcctgtc cagcaacctg ggaccaacaa actagacatc agttcctatg aatctgaata     2040

tacttctagc acattgctcc catatggcat taaatccttg ccccttcaga catcccatgc     2100

cctggggtat tacccagacc caacctttcc tgcaatggca gggtggggag gtcgaggttc     2160

ttaccagagg aagatggcag ctggactacc atggacctcc agaacaagcc ccactgtgtt     2220

ctctgaagat cagctctcca aggagaaagt gaaagaggaa attggctctt cttggataga     2280

gacaccccct tccatcaaat ctctagattc caatgattca ggagtataca ccagtgcttg     2340

taagcgaagg cggctgtctc ctagcaactc cagtaatgaa aattcaccct ccataaagtg     2400

tgaggacatt aatgctgaag agtatagtaa agacacctca aaaggcatgg gagggtatta     2460

tgctttttac acaactccct aaagagttat tttaacctca aaaattagct aactttttgc     2520

agatggactt ggtggtgttt tttgttgtct tctttgccta ggttgccaaa aagatgtttg     2580

ccttccacct tgatgcatcc tgttttgtgc aattctctaa aagaaggtgc caaagctttt     2640

tgattgctgc aggtaactga aacaaaccta gcatttttaa aaaataagat taatggaaga     2700

ctttaaggta ttttaaaatt cgaagggtat ccaaggttct gtatttattt attggggaga     2760

cactaaccct tcaaagaagc aggctgtgaa cattgggtgc ccagtgctat cagatgagtt     2820

aaaacctttg attctcattt ctatttgtaa attcttaagc aaatagaagc cgagtgttaa     2880

ggtgttttgc ttctgaaaga gggctgtgcc ttccgtttca gaaggagaca ttttgctgtt     2940

acattctgcc aggggcaaaa gatactaggc ccaggagtca agaaaagctt ttgtgaaagt     3000

gatagtttca cctgactttg attccttaac ccccggcttt tggaacaagc catgtttgcc     3060

ctagtccagg attgcctcac ttgagacttg ctaggcctct gctgtgtgct ggggtggcca     3120

gtgggactca ggagagagca agctaaggag tcaccaaaaa aaaaaaaaaa aaaaagggag     3180

aatttaaaag tgtacagttg tgtgtttaga tacactatag aataatgtgg tatatattgt     3240

acaaatagtc tacataggtg tctgggataa tgtaaaactg gtgctttggc tttgtaaaga     3300

atttgcaaat cacttaacag ctgcaggggc aaggggagag tttcatcatc cccatgatat     3360

ttgggaatat tctgtttact tcttagatag ttaagaatgt attcagctac tatgtactaa     3420

cttgaaccgt gtttaaggaa aactcctatt tcatcctctt cttgcgccat cccctctccc     3480

taacttggta atgtgaagaa actaaaacct gataccacag ctcctatagg cattttagag     3540

atcttggatt tttatgtaca gtcttagtca tttttaataa atgtggttca gtaagggaac     3600

ggaaaaaaaa aaaaaaa                                                    3617


<210>  914
<211>  12021
<212>  DNA
<213>  homo sapiens

<400>  914
gggtgatgtc agctctcgac gaaaatagag agggatcgcc tgcaaatccc cagctccggc       60

ggggctaaac cttgcaatcc ctccctggcc ggcgccgagc cagagcgcag cggcctccac      120

cgcctcccca ggcgcgcaca cacccgcaca cgcgcacgca cgctcaccgt cctctgccac      180

cactctctgc tcccgccact cgccgcgccc gcgagccccg cagcaaagca caggtggcag      240

cggctgcagg ggcgcatcgc cggcgtgcgc cctcctgcag ccctgggcgc atcgctctct      300

cggggaagcc accctcggag cccccggagc tccccgccaa gcgccatccc cgcgggcgga      360

ggggagcgcg ggtcgcgcgc cgtggagagc cgggacgcgg attagcgccc gcaggagcct      420

cctgcgcccg ttgaggcgct aaagggctta ccccggaggc gggtggaagg gcgggcagag      480

gctcctctta aataccgctc ccggccgcac ttcgcgctca ccccggcgtc cgctttctcc      540

ctcgcccaca gctgccggat agtgctgaag aggagggggc gttccccaga ccatggcatc      600

tacggaaggt gccaacaata tgcccaagca ggtggaagtg cgaatgcacg acagtcatct      660

tggctcagag gaacccaagc accggcacct gggcctgcgc ctgtgtgaca agctggggaa      720

gaatctgctg ctcaccctga cggtgtttgg tgtcatcctg ggagcagtgt gtggagggct      780

tcttcgcttg gcatctccca tccaccctga tgtggttatg ttaatagcct tcccagggga      840

tatactcatg aggatgctaa aaatgctcat tctccctcta atcatctcca gcttaatcac      900

agggttgtca ggcctggatg ctaaggctag tggccgcttg ggcacgagag ccatggtgta      960

ttacatgtcc acgaccatca ttgctgcagt actgggggtc attctggtct tggctatcca     1020

tccaggcaat cccaagctca agaagcagct ggggcctggg aagaagaatg atgaagtgtc     1080

cagcctggat gccttcctgg accttattcg aaatctcttc cctgaaaacc ttgtccaagc     1140

ctgctttcaa cagattcaaa cagtgacgaa gaaagtcctg gttgcaccac cgccggacga     1200

ggaggccaac gcaaccagcg ctgttgtctc tctgttgaac gagactgtga ctgaggtgcc     1260

ggaggagact aagatggtta tcaagaaggg cctggagttc aaggatggga tgaacgtctt     1320

aggtctgata gggtttttca ttgcttttgg catcgctatg gggaagatgg gagatcaggc     1380

caagctgatg gtggatttct tcaacatttt gaatgagatt gtaatgaagt tagtgatcat     1440

gatcatgtgg tactctcccc tgggtatcgc ctgcctgatc tgtggaaaga tcattgcaat     1500

caaggactta gaagtggttg ctaggcaact ggggatgtac atggtaacag tgatcatagg     1560

cctcatcatc cacgggggca tctttctccc cttgatttac tttgtagtga ccaggaaaaa     1620

ccccttctcc ttttttgctg gcattttcca agcttggatc actgccctgg gcaccgcttc     1680

cagtgctgga actttgcctg tcacctttcg ttgcctggaa gaaaatctgg ggattgataa     1740

gcgtgtgact agattcgtcc ttcctgttgg agcaaccatt aacatggatg gtacagccct     1800

ttatgaagcg gtagccgcca tctttatagc ccaaatgaat ggtgttgtcc tggatggagg     1860

acagattgtg actgtaagcc tcacagccac cctggcaagc gtcggcgcgg ccagtatccc     1920

cagtgccggg ctggtcacca tgctcctcat tctgacagcc gtgggcctgc caacagagga     1980

catcagcctg ctggtggctg tggactggct gctggacagg atgagaactt cagtcaatgt     2040

tgtgggtgac tcttttgggg ctgggatagt ctatcacctc tccaagtctg agctggatac     2100

cattgactcc cagcatcgag tgcatgaaga tattgaaatg accaagactc aatccattta     2160

tgatgacatg aagaaccaca gggaaagcaa ctctaatcaa tgtgtctatg ctgcacacaa     2220

ctctgtcata gtagatgaat gcaaggtaac tctggcagcc aatggaaagt cagccgactg     2280

cagtgttgag gaagaacctt ggaaacgtga gaaataagga tatgagtctc agcaaattct     2340

tgaataaact ccccagcgta tcctatggta actgatgata taaacaagct ttctttaaaa     2400

aggaaaaaaa tgcgtatatt tctatgttta cttaatctgt tagccgaggc ttagaggagc     2460

tcttgtgagt cagtgatgac aggcacggtg ctgtgtcttt gccaaataat gctttataac     2520

cgtctaattt tctcacttgt attattattt gaatggatgc tgctggagga atcagttgga     2580

attgaagaca cgttcttgcc agcttccctt ttctcccaag atgcagaaat gtggatgctc     2640

ttttcccagg ggacatgagt aaagcagtgt ggtacactcc agggacttgg gaaaatgagc     2700

aaacacacag cgtgttattc cttaaagtgt tctccatgtc tcgccttgtt atgcacaaga     2760

gattctatta aaagcctcta gaagtaactc cccttaaaat gtctagtaaa gcttgcacat     2820

ggattgatta aaagcaaata cctgtcttag ggaattctga caatttatct tccatatgct     2880

ctttaagtaa aatgtttcaa agacagtttt aaagggagcc atgctcttaa aggcagttga     2940

ttaaagaacc tgttacatct ctgccttacc ctgtgtaatc tgtgagaaca atggttgaaa     3000

tttcaaagta tgtttcatta ttctttctaa atttgataat tgattaggaa gtattttata     3060

tataaccact gtagatattg acaaaagtaa gagagcacag tcaacataaa gtttaaccag     3120

agttaaatat tcaaatttat ttatgttcgg tttgccttca cctggtgtag taaaatcaaa     3180

tgagattatt tggtatgtgt tttgctttgt ttaacccaaa agattatttt ttggttccta     3240

aagaaaaaga tatttttaat ctgtcaatta tttcagtcat catctcatcg tcctagaaag     3300

cctggtcatt ttactgtcct cacacatgga agacacttgt gttggctgtg cctcttttaa     3360

tgtcatctct tgatgaaaca aaaatactgg tatttatcca atatgttgaa agcgttttgt     3420

tatcttctat caaagcacat aaaaccagtt ataggacaca gttggaagca gagccagtct     3480

tcctcctcag tcttctcagt agaaaggaac agaaaacaaa catctgtgca aaaccctata     3540

aaagtgatat tcctatggca gagtccaggc agccttgaac aatgacatgg caacaaagga     3600

tggctctgta caacttcaca gatggaatct tgtttaaggc tgtgaagttt taaggaataa     3660

ataatataat tggtgtagca cagtgccttg catgcagtag gcagccaaca aatccttaat     3720

gattggtaat gcaagctaaa atttttaatg tctctactat ccttttttat tgaataacgc     3780

acagtatttt cctaaggttg ctgggtttgg gagtaagctt gggacttgaa tcattgagaa     3840

ataaagcaca tttgactcta agaagtatgt agaaccttgt ttataggtga gaataggctg     3900

tattatatga aaccagcgga gggatgctga gacagtcatg gtttatagaa tccaaattct     3960

ctgagatgag ggtgcttatg gacctcaaat agcctttctt atctgctcct tgtgacttct     4020

ctcttttaaa tcagatacct ttgaaacata caagagacat gagattccag ttgtttttgt     4080

ctcctaaacc ctagtgattt ttggataagg atcactactg aacagtatta ggcaactttt     4140

catttttgct tttcaaatga cattggtctt tatttccagt agatgggcag taaacagggt     4200

cagggtggtc aagggatatg attaagtgta gtagtagaaa atgcattctt tttttttttt     4260

tttttttaga cagagtcttg ctctgttgct caggctggag tacagtggca cgatctcagc     4320

tcactgcact gcaatgtcca cctctctagt tcaagcgatt ctcctgtctc agcctcccga     4380

gtagctggga ctacaggcac atgccaccat gcctggctaa ttttttgtat ttttagtaca     4440

gatgggtttc attatgttag ccaggatggt ctcgatctcc tgacctcatg atccacccgc     4500

catggcctcc caaagtgctg ggattacagg cgtgagccac cgtgcccggc cagaaaatac     4560

attctttaca gcaaatgtta taggttaagg agacagttcc tgggtttagc tgtgaaactg     4620

tttaggattt tctttaagtg gtgttcccaa gagctttttt ctggtaagtt ggaggctata     4680

ggcaaagcgt ctaggagctt gttgtttttt gctatggaag gccagctttg ggatctatat     4740

acatgggcat gtttctcaat ggagtggtca caggattctc ttctcagaac tctgcctgaa     4800

acctttccgg tgtgttttgt cttcaacttt ttcctagcta tcctattagc ctgtaaatat     4860

gtcagcagac aatgtgtttg gaagaaacaa ggtgtacaac ttcacaaagc aagttttttc     4920

tggtctgaga cttactgtgt gcaggaagtc tcgtgagaat atacttagaa aatcacactt     4980

atctggaaat tcaataagtc atattaaaaa tatacaattt cttgaactca ggactagcct     5040

gaaaatccaa aatgcatgta gagttgacat gttgacatat gtctatgtcc tctgttttta     5100

tttaagcctc atttatttct cccttgccat gcccatttgg gattttcttt gcccagcata     5160

tgtgccataa acagaacaaa tggatccagg gtatacctct aataaccttt atctaaatag     5220

aatacattta acctgtcaat tatatgtata gatttatcct aattggttca acatatatat     5280

gaatgcttgt aatagtctgt tactatttga taatgcataa atgttatatt tatatacagt     5340

tacagcaggc cagaaacata catacactgc atcctgtaag gtctgtaaat cagggcttcg     5400

gcaatgccat tttgctatag actcattcat gttttttagg aatcagaatc atttcaggag     5460

aaaaccaact aagtagactt taattcttct ctttctcatt cttgcccttt gagaaaccca     5520

agtggaatca tcacttaatt acttactcaa attcaatgaa tcaaatccaa tccaatcagt     5580

gagaagaata gcttatcttt caaggtaata ctttacctta gatctttgag ggcatgcttc     5640

ccatacaaag agcatcagaa aatcagggca atcatctaga tctcacagat cttcaacata     5700

ggactctagg ttatgagagc tgaaccacat agctatcagt ttcagttttt acttcctatt     5760

gagtgtgtag aaacacagcc tatggttttg ctgtctgcgg aagttaccat accctgtaaa     5820

agacaaatat ttctttctcc tctcgaacca ctagtcagcc tggatattca tgaaagctga     5880

aagaaggggt gccaaaatgc ctagctcctg gatttagact catggaatat gagaaaggct     5940

tagggaaaat tcaagtcatg gggagattcc tgctaggtga tgccaggaat ctcaatgacc     6000

tgttgattag agggtctctg gtcatttcca cttgtgtgtg gagaaataca tcatttgcat     6060

atgtatctag tcaagaagcc cttttggagc aaagtggttg ggaaactcat ttactgggtc     6120

caccaaagga aacccaattc tgccatgttt ttgcaaatac tacacgtccc tttgctctca     6180

atagcaaaag tgatgttata gtttttttta cttttgtcag aatcaaggct tcggccacct     6240

gtgcaatatt ttcccatgga atgcagcagt aaatccaagt aggtatatcc gtgctcagag     6300

agaattctcc atagttctga ctcctgaaaa acaagtctca ttagctctca tctagtttga     6360

tgactaaaag tgcacagcag ttatacccca gtggaagtga tttttctcac ctagctgctc     6420

tctaactctt acggctatct agttgtctga gctgctggtt tgttttactt attctccaac     6480

tgaactcatt ccaaaccaag aaaaaggacc aaatgaaatt ttcagttatt atcatacttg     6540

ctccttgaat aagaatgcta gagtctggag gcagaagaag actaagttaa aaaaaaaaca     6600

gcctgaagga attctggagt gagttttgta agtctaattg tcaaagaaga taaatggtct     6660

cagtatctgt agtaatttct ggttaagcct agagggatca ctgagtgcca atccaagcag     6720

gtggcactag aggcagattg ttctcctagc atagagtgag tttccagctg ctcatgacac     6780

attttcttat gattttccct aaaagaaaac caaattttct actccacctc ttcctttcct     6840

atcattccac ttattgttgc tgctttgcta acagccagct tagtaagcca tcacacaagt     6900

tagtgtgagg cttggtttta aaatagataa cagagaatct tgattaaata gtatccaact     6960

ttgtagcata acacagctaa ttcaggcaat gacatagaga tgataagaaa caacatggtt     7020

tggtagaggg aacatttgat ttagactctg cccattttta gctgtatgac ttacataagt     7080

cattttgtgt ccaagcctca ttttctccca tatgaaaagt gaaggggttg gattaaatga     7140

ctaaaatccc cttccagccc tatgagccca atgtattatg atctctgctt tgtttccttc     7200

ttaagaggct tcctactata aaatgtgacc tatttacatt ttaagttgaa gtagcccaca     7260

ataatgaata atcaatttag atttttctca tctcctttgg gagaaattaa attcaagcct     7320

ctattcattt gatgttttac aacaagcttc aaagttggcc atgttcattc acagtttgat     7380

attttgagac accaataaaa gttttttaat aaaagttccc ttgacttaaa ctcaccttcc     7440

taatagaagt agtgatttgg ctcacggaaa aatgtttcca gagtcaacat gagaggactg     7500

gatgaaccta cagcctcact caagctgttg catcattgct gctgtagcaa cagagccctc     7560

tctgaatacc caaaacacac aattttctcc aacaattcta attgcccacc cagtatggga     7620

atttgagagc ctttggtgaa taaccttgat cactcttttg aaatttggta caacacttgc     7680

acaatcacgg caactgtttg taaatatctt ttcttctccg ccagtatgta gacatgcaca     7740

cccattcaca agtaagcccg caaattcatt ttcacatttt cctcttggtt tgtttttatc     7800

atgggtatca cattgcagga agagatgctc taacttacaa gaatggaatt ttctgactat     7860

cattgccctc ttcaaggcct gattagtttg tagggtggat gggatacaat gcatggtcta     7920

caaggtccat gtcaccagcc atgatcttta aacaacctct tgcactttct ggcactgctg     7980

caatggccca tggtggacac ctctgctgtt tgtccaaact tctgctaaat agagtagtgt     8040

tggtatttgt tgtgttgtga actcctttgt tgtcagagaa gacttcagct cttcaggttt     8100

gcaagggcaa gatgtaaagc taggactgaa aggattgggt tttgtttttc ggccggcttt     8160

tttccattag tgcaaaaaac ctgatgcaag ggcagcaaga taaacacaat ttcttcattg     8220

acccagataa gaacctgtag aaaagtgaga gatgccccta agttcctatt tcatttatcc     8280

taaataatat cctgaataac tactgatcag tttttttcta tgtccagcct tgcttcactt     8340

tccaacctcc aggccaaata ttcattttga tattttacaa aatccttctg gtttttacac     8400

agggcccttt tgtgctgaga ataaaaccag ctattggaac agacctcact gctttgtaga     8460

gtcagaagtt gacctagaga atgggtagca acaggtcctc agtttctctg gagacacccc     8520

caatccttgg gtgagtgttg aaacctgaca actgactgtt agccttgtca tcatcctcac     8580

tggagatgga gatgttgcag tcggagcctc actccttctg gggcactgtt tcttctcatg     8640

gcaaccattt tgcctgcctg gaaacagcct gttgcctttg ctagggggca aatacacaca     8700

ctagccaagg aagttggtcc agcacatctc tgaggtttct cccccatgga cccatggagc     8760

gaattccctg agataaatga tcagaaagtt ggctgtctgg tggtttaata ctccataaga     8820

gttacttccc ttatagaaag tcatcctttg gcatctagat ttttctacaa atcaccttaa     8880

ctccctccct ttctctttct cctggaaaac ctcagcattg catctccatg ttgcacaaca     8940

cagatcagat tatctggtca ctatagagat ttgtatataa aaaaactact tttttgagga     9000

ttttgtatat tgtttttcta tttgttttct acagcttgag gaaagagctg gcaaactgtg     9060

aatctaactt gatcttgttg ccagcagata tattttggct tcctggtaag agtctgtgtt     9120

accagggaca atatattgcc ctctgatcag tattgcaccc taaatccaca aattcctcca     9180

gcccagtctt acattttttt aaacaaatcc cctagcttgt ttgctattat ttataaagag     9240

cattagaaaa tgtatttata gacctggatg ttatatgttt aatattaatt tagcctttaa     9300

taatgttata ggtttgtaac tattcttcag aaattataaa gaactcagtg tagactgaat     9360

taatctattt agtatctgta attttgcaga catattttct tacagtattt tctatgtaac     9420

cacacatgta gaattataac taattagagc acaagaagtt tcttcagcaa tttagagcta     9480

ccaattgttt cttgactata tagtcacatt tgacaaattt aagaacccag tctttagtga     9540

tgcaataaac aaaatgaacc attaagaaca aggaattgct taaatccctt agctggtgag     9600

gatatacatc taaataattc atctttctaa ctcaaggaat ggtgctgatt ttttaaatgt     9660

ttgacaccag gccttgtttt tccagctgag cattctcatt ttgcttttct ctaagactat     9720

caaagacaag gtattaatag taggattatt cctagatcag aatgtttcat acattcctaa     9780

aggtttatgt ggaaattggc ttaggaaaac tttgagtagc agagactgag gatgagtgct     9840

agagatgaaa tcaggacaga tttgttgcag ttaattcttg ccaagcaaat tagtggtaaa     9900

tgtcacattg ttatgtgaat tgagcacata tttttaaaga aagtttacaa aaaattttta     9960

gaaccaacta tgaggcaata ctgtatcact gggggctggg agtgggggct tagaatcata    10020

ctgaaattgt ttaaaagcag cccaggtagt ttctgtcctc aggtgaataa cagactatat    10080

aacttccccg aaaggtaaaa cgatagccac tgcagagacg aggtgtcttc cttccaccaa    10140

atactttctg agatggtggt aggagtagta tttttaccgt ggtttaaaaa gtagtcagtt    10200

acatagaaag tgtattggta tgtatttgaa cctgctcttc attaaacaaa cagattagat    10260

gtaccctcga ctggcaataa ttgtatctat tttcaagtac agctagctgt caaagcatga    10320

agctcttgtg tatacacact gacacttggt tcacgcatga agaacagtgc ctatgcactt    10380

tgtgtagcta taatgtaggt atctaggtgt aatttcagtg aaatggtgta tagatgtatt    10440

gtaatttaaa tgtatatgtt atttttggct attcatctaa atgcagtaga catgttgatc    10500

ggtgttttgc aaacatttct ttttccttct tagataacta gtcgtgaatc atttctcctc    10560

tttctcagtg tggcttggga atatatatga gtgaagaatt tatctgtgaa tcctttgtac    10620

tgatgattgt ttgaaagtct gtgtgtgtcc agcacctttg taaatacaca attcagagca    10680

gggatgggct gggtgtgtgt cctggttctt agtgaaaggt catctcatgt ctgtttaata    10740

catggtgaat gcaactgtgg aacttttgat tacctagact taggtaggtt tagaatgaga    10800

acatccatct acagtcctcc tttgcttggt ggattgggct cagaggaaca aaaagttagt    10860

ctgactctgt gcatattagc atcatgtctt tagagaaagg tcagcctctc tggttgccaa    10920

atactcatca tgatgctcat gacttaaagg ttctgaggag ccttgtctcc cttggatttt    10980

tgagtcaggg tacaggaaaa aacattgctg actaactaac tgcaaatgca tctgcaggtg    11040

aaaccctacg aaagcacagt tctggctata aacttcagag ttctctgtaa aaaacttaga    11100

gcactagaag cacaggaata gtgagtgtac agcttatgcg gttgtagagg ggcaactgat    11160

gaacacaggt cccacatata tgagggagta tgacgttctc tacctaatat gttctgtgtg    11220

catgttttga atgattgaag atgggattaa ctaatgcaag tttacagttg cctcctaaaa    11280

cacacattct gtataattat cgctaaatac aatgctgtga ggtctatagt tcctgtaacc    11340

cctttctcct ccccaaggac agagaagaac tagccatgtg ctatagggaa ccctgagtgc    11400

cctactcttt tcccaagaag ggtaaagcct acaatatcat cagggggcat gaagcacatt    11460

aatttgcagt ggctgcttca tatgaggaga tatggtggac aggctaattt ttccttgaaa    11520

atgtggcttc ttcaactcct ttcaaattta ggatggaata cttcctgaaa taaaactggg    11580

ctttatgcag gattctcttt gaaaattctt gtatgtccag aacaaaagat aaaactaatt    11640

gtattcctca cattcacaat ccccattggt ctgaagtcac gtagcacaga gcatctatag    11700

cacatagtgt ttaaagacta atgaatgcaa aaagataaaa tcttcaacta atttttgaat    11760

tgtttctcat atatgctact agaaaatgcc ttgttgatga agcacatttt gggtagttga    11820

ggtcttttgt tttcgccttt agctttctaa gctttcttac aatgtggact gattactgta    11880

acatttcacg tgtaaaataa ctggatattc tttatatact ggaaataacc tgtgaatcca    11940

atatttcact aagtgtttta acttttgtgt atatatctct catcaataaa tgtggatttc    12000

aatttaaaaa aaaaaaaaaa a                                              12021


<210>  915
<211>  2511
<212>  DNA
<213>  homo sapiens

<400>  915
agagccagcg gacggaacca ttccaaacag cctagtctcg tgctgagagc ctctccggtt       60

tcacgctgag acccgctcac ccccgctctg gccccttaga tgctattttg gcccgagtgt      120

cacgtcgggc gctctttaga gaggactggg acaagagttg cggacgcgaa gaacgagtaa      180

gcggtggttc atccctcctg accccacccc cgtggcctgg cccgatggtc gcgcccgggg      240

ttgcgagatt tgcgcctgcg cagtgcggcg cctagaggga aagcgagagg gagacggacg      300

ttgagagaac gaggaggaag gagagaaaat ggcgtccacg gattacagta cctatagcca      360

agctgcagcg cagcagggct acagtgctta caccgcccag cccactcaag gatatgcaca      420

gaccacccag gcatatgggc aacaaagcta tggaacctat ggacagccca ctgatgtcag      480

ctatacccag gctcagacca ctgcaaccta tgggcagacc gcctatgcaa cttcttatgg      540

acagcctccc actggttata ctactccaac tgccccccag gcatacagcc agcctgtcca      600

ggggtatggc actggtgctt atgataccac cactgctaca gtcaccacca cccaggcctc      660

ctatgcagct cagtctgcat atggcactca gcctgcttat ccagcctatg ggcagcagcc      720

agcagccact gcacctacaa gctattcctc tacacagccg actagttatg atcagagcag      780

ttactctcag cagaacacct atgggcaacc gagcagctat ggacagcaga gtagctatgg      840

tcaacaaagc agctatgggc agcagcctcc cactagttac ccaccccaaa ctggatccta      900

cagccaagct ccaagtcaat atagccaaca gagcagcagc tacgggcagc agagttcatt      960

ccgacaggac caccccagta gcatgggtgt ttatgggcag gagtctggag gattttccgg     1020

accaggagag aaccggagca tgagtggccc tgataaccgg ggcaggggaa gagggggatt     1080

tgatcgtgga ggcatgagca gaggtgggcg gggaggagga cgcggtggaa tgggcagcgc     1140

tggagagcga ggtggcttca ataagcctgg tggacccatg gatgaaggac cagatcttga     1200

tctaggccca cctgtagatc cagatgaaga ctctgacaac agtgcaattt atgtacaagg     1260

attaaatgac agtgtgactc tagatgatct ggcagacttc tttaagcagt gtggggttgt     1320

taagatgaac aagagaactg ggcaacccat gatccacatc tacctggaca aggaaacagg     1380

aaagcccaaa ggcgatgcca cagtgtccta tgaagaccca cccactgcca aggctgccgt     1440

ggaatggttt gatgggaaag attttcaagg gagcaaactt aaagtctccc ttgctcggaa     1500

gaagcctcca atgaacagta tgcggggtgg tctgccaccc cgtgagggca gaggcatgcc     1560

accaccactc cgtggaggtc caggaggccc aggaggtcct gggggaccca tgggtcgcat     1620

gggaggccgt ggaggagata gaggaggctt ccctccaaga ggaccccggg gttcccgagg     1680

gaacccctct ggaggaggaa acgtccagca ccgagctgga gactggcagt gtcccaatcc     1740

gggttgtgga aaccagaact tcgcctggag aacagagtgc aaccagtgta aggccccaaa     1800

gcctgaaggc ttcctcccgc caccctttcc gcccccgggt ggtgatcgtg gcagaggtgg     1860

ccctggtggc atgcggggag gaagaggtgg cctcatggat cgtggtggtc ccggtggaat     1920

gttcagaggt ggccgtggtg gagacagagg tggcttccgt ggtggccggg gcatggaccg     1980

aggtggcttt ggtggaggaa gacgaggtgg ccctgggggg ccccctggac ctttgatgga     2040

acagatggga ggaagaagag gaggacgtgg aggacctgga aaaatggata aaggcgagca     2100

ccgtcaggag cgcagagatc ggccctacta gatgcagaga ccccgcagag ctgcattgac     2160

taccagattt attttttaaa ccagaaaatg ttttaaattt ataattccat atttataatg     2220

ttggccacaa cattatgatt attccttgtc tgtactttag tatttttcac catttgtgaa     2280

gaaacattaa aacaagttaa atggtagtgt gcggagtttt tttttcttcc ttcttttaaa     2340

aatggttgtt taagacttta acaatgggaa ccccttgtga gcatgctcag tatcattgtg     2400

gagaaccaag agggcctctt aactgtaaca atgttcatgg ttgtgatgtt tttttttttt     2460

ttttaaataa aattccaaat gtttataaag agtcaaaaaa aaaaaaaaaa a              2511


<210>  916
<211>  8005
<212>  DNA
<213>  homo sapiens

<400>  916
ggggattggc ggagcgcgag gagagaatgt gacaagtgcc ggctcggcgg ccgccggggg       60

aggccgcgcg cacctgtccc tgcccgtctc gcgccgcccg cggccgctcg gacgcgcgca      120

gagccgcccc ccgccgctgc cgccgcgtgc gcccgcgaac atgacttctg ccttcaagct      180

ggatttcctc ccggacatga tggtcgaggg ccgcctgctc gttcctgaca gaattaacgg      240

cacagccaac aagatgaacg gagctttgga tcactcagac caaccagacc cagatgccat      300

taagatgttt gtcggacaga tcccccggtc atggtcggaa aaggagctga aagaactttt      360

tgagccttac ggagccgtct accagatcaa cgtcctccgg gaccggagtc agaaccctcc      420

gcagagtaaa ggttgttgtt tcgtaacatt ttatacaaga aaagctgcac ttgaggccca      480

gaatgcactg cacaatatta aaactttacc tgggatgcat catcccattc agatgaaacc      540

tgcagatagt gaaaagtcca acgctgtgga agacagaaaa ttgttcatag gaatggtatc      600

gaagaaatgt aatgagaacg acatcagggt gatgttctct ccatttggcc agatagaaga      660

atgccggatc ctccggggac ctgatgggct gagtcgaggc tgtgcgtttg tcacattttc      720

tacaagggca atggcacaga atgcaatcaa agccatgcat cagtctcaga ccatggaggg      780

ctgctcttca cctatcgtgg tgaagtttgc tgacactcag aaggacaaag agcaaaggcg      840

cctccagcag cagctcgctc agcagatgca gcagctcaac actgccacct gggggaacct      900

gacagggctg ggcggactga ccccacagta tctggcgctc ctgcagcagg ccacctcctc      960

cagcaacctg ggtgcgttca gcggcattca acaaatggca ggcatgaatg ctttacagtt     1020

gcagaacctg gcgacgctgg ctgctgctgc agctgcggcc cagacctcag ccaccagcac     1080

caatgcaaac cctctctcta ccacgagcag cgccctggga gccctcacga gtcccgtggc     1140

tgcttcaacc cccaactcca ctgctggtgc agccatgaac tccttgacct ctctcgggac     1200

tctgcaagga ctggctggag ccactgttgg actgaataat attaatgcac tagcagttgc     1260

tcaaatgctc tcaggtatgg cggctctgaa tggaggactt ggcgccacag gcttgacgaa     1320

tggcacggct ggcaccatgg acgccctcac ccaggcctac tcaggaattc aacagtacgc     1380

agccgccgcg ctgcccactc tgtacagcca gagcctgctg cagcagcaga gcgctgcagg     1440

cagccagaag gaaggtccag agggggcaaa cctctttatt taccaccttc cacaggaatt     1500

tggagaccag gacattctgc agatgttcat gccttttgga aatgttatct ctgctaaagt     1560

cttcattgac aaacagacca atctgagcaa gtgctttggt tttgttagct acgacaatcc     1620

agtctctgca caagctgcta tccaagctat gaatggcttt cagatcggca tgaaacgctt     1680

gaaggtgcag ctgaagcgtt ccaaaaacga cagcaaacct tactgatcct aaccccagag     1740

gctccctgct ctcattttag ctttcttagg acatcttcat gcccgttagt tcatcgtttg     1800

cctagcatgt ccctgtggcg tctcaaaaaa aagtttcatc gtcccgtcat tgtttctgat     1860

gtctttctga cctcacatca tatttggttc tcctactgac ctttgatcta gtttgacctt     1920

tgaaatttgc atgtgacctc atctagctat gaattctggg aagtcaatgt gaaaaacatt     1980

gctgcattca tgcaagactg aaatttatta ttagacaaat tcattataga aaaaacctgt     2040

ggcaaaaacg tttctttctt attttttttc ttttcctaaa acagacttga aagtattata     2100

cagggattgg cattcttccc ggtcactggt aacaatagca atatgtgtcc agggacacag     2160

aatgttggtt tctaacagac tacttccaaa aacagtttga gaaaaaaact gtctgatttt     2220

aagtctctag aggtctgtaa tagtttttac atttttcagg cagtgtaaag ttttttgata     2280

aggccatttt aggtggctca ctttctcatt aagatatata tatagaacca ctttttgtag     2340

attagtataa gaaaaatatt taccctgttt tggggcaaat gctacctatt tgtgtcacct     2400

tttgctgaac tcacagttag acaatccatg gtttaatgca catgaaatta cctatatttt     2460

atactgtttc aatgtacagg agaaaggtta ctgtaaactg tgttatgttg gtgcttctgt     2520

gaattaagtt gtggtttcat catgagtctt aatgttcttt gttgataaga caagtttaga     2580

attggtttac ttaatacaaa aaaaaaaaaa agaatttcaa aaaaaaaagt tgtttgctta     2640

aaaaaaattt catgtgaggg aaaaaaaaaa aacctattcc agaataagtt ttgtgttggc     2700

ttgtgaagca ttgatgtcat tttttttaat tgtggactat ttagatgtgt ttgtgttcag     2760

caaaatgtga tctgtttttt tcttttaaag aaaaaaagtg aaaatatata gtgccaaatt     2820

ccaaaggtac ttccttccta gagcttcagt gtgtttcttg tgagaagtaa tttgataaca     2880

tgggtatttt attatgtgtt ttgtataaat ccctaatatt taaaaaaaaa aacaaaacaa     2940

aaaaaggtta caaagtttgt taacttgcta tcctgtggtc ttgttgcctg aaattgttat     3000

tgtttgttat ttctctctga tgttttttgt aagacattgt ataagtgccc atgtcccact     3060

tttttaacca ctccgcacat cagtgctgtg aaggcaacct caccatgtat tttcttcata     3120

atctatggaa acctctaagg tgagaaagtt ttgaactttt aaccctttct acccagagct     3180

atctggaatg ttgatgactt tttatactgt catgatttga gtttgttttg gggtgtttcc     3240

aatttggatt tttttccctg catctatcct ctaagttgtt tcggtttgac tactttgttc     3300

tttggttaag atccaaaaga aaacagaaaa caattccacg aggccaatct aaagggaaaa     3360

aatcctacac tacttttact acttttgatt atttctcatt tttgggaaaa gaattcctaa     3420

tgtgctacta gaattccttc ttcagtttta acgagtaatt ggataaaccc tgagggaaaa     3480

cggaggtaga ttcagcacct aacaatcctg tatgcttttg agatcacgtt tagtgctatg     3540

tcctagtcta gaatattttc atataccttg cagtaaaacg actttgtggc aggacagtct     3600

cttgaggggt tttgtttctg tttcctaaat actcctaaat aatatttcta atcagccatt     3660

atgctggggc atctctgatc ccagtaggta cctctgaata taccaggtgt ctggagttag     3720

aagcccatag ccctttccca gcctttttgg tttttttaat tgaacacatt tcatctaagt     3780

aaagctcagt tctttatcac aatttactga ccaaatacct agcaccagtt cctgctgcca     3840

ctttttaaag tgccatatga ctttctacga acaggtacct tgctgtcttg acaaatccta     3900

atgtcacgcc tacagcccca acacaagctc cagtcttcct cttcggcatg ccctggaagc     3960

ttcttggcct cagctcccct tccccgctca gcaccctgtt aggatcagtg tgtgtggatg     4020

ggatagccct gggatggaaa ggactagcct ctactgatgc aaaaaaacaa aaagcaacac     4080

aaacgtttcc ttcttatagc acatgcactt ccttacaatg acatgatttg tattatcctc     4140

acatgtgttt actactgctg gggccttcct tcatcctctg agggctattt tgtactttct     4200

gcagcaatca gcttaataac aacacttatt gcacctgtct ctctctgaga acacggtgtg     4260

tctcgacacg taccacgtac gtggaaacac aagagcccac cacttgaatt tctaagacca     4320

tttcattctg aaacttctta tcaattacct aaatctcaac gaaaaacaat ttactgaagc     4380

cgactcccct ccccatctcc ctctcaacct caacccacct gcatgcatct cccccagagg     4440

aaacactgag ggtaggggac aggaggctca ggacgcgccc tctgaatcga gtgtttcttc     4500

ttcacaagtc accaagagag gacatgaggg ggaaagtcct tttttgccct tctccaaaaa     4560

ataaccttcc acagagacaa actgtccttc tatccacttt tatcttttaa taaatatcaa     4620

aaggaaaaag ctgcaagggt gcaaagggcc tgtgccagaa gaaaacacac acagggaaac     4680

cgcttttttt aatcaattgt agagaatagt catttttaat ctaaattaga gaattgtgat     4740

acaatggcag tcctcaaagg cgtaacgagt tcatctttct ttcaccatag gggttatagt     4800

tggcttgtgc tactctggaa tcattttact gtttgttttt attatcttaa gtgctaatta     4860

aaaaaaaaat aaaattttaa aaaaacctgt agtttcatta cctttttgaa taatgtcata     4920

caaaaaatgt atttgttttt ttgtgctgtg agaattgatg tttgtagatt aataatcatt     4980

ttgtttagaa ttacaaaata gtttttaaat attgtctgag aaaagccaaa gttaatgcaa     5040

cctagtggaa actgtaagac catttgagta ttgtttgttt tattgatgca tttggatttt     5100

gttgtttgat ggaatttgag ccaaaaaaaa aatacgcagg ctttcctatt tctacaactg     5160

attgtactta tgcattttgt accagtggaa ctttttatac tggagattaa aaaaaaaatg     5220

gaaatttttg tggcttgctc tggtgggccc ctgacaatga ctgatttcaa gtttgatttc     5280

gggttgattg attgattgat tgatagaaag aaagttgctt ttcttttgag aattaaaaac     5340

tttggcttga tttctttttt ccctttgctt atatctagca ttagaatttt gtcttaaaat     5400

aacagcggta agtttcactt tttattctgt attgtgcagt tacacaataa ggtaattaga     5460

tttagaagta ctcagtcact ttaagtggat aaatgtatta gttaaaactt tagggtttgc     5520

ttttttgctg tttagatcaa agttttttct gattcttctg tcctcattgt gaacataacc     5580

gtgtagttga aacagtcaaa cttatttttg taatgtatgt tattgtgtga tgcagttttt     5640

tgcttctgtc tccaatatta aaccattttc ctaatacttg tttctctctc tgcgtgttgt     5700

attgttggta gtcattatat gttggtgata catctgcaca cctcactgtt tcacgtatct     5760

gtttttttct ctatgttgtg taaaaagata cagtcgattc cacttaagtg aatatctgat     5820

ttggggaaga ggaaactgca cagcagccac ctttgattta tgtacaaccg cccacttgaa     5880

ctcctgcttc caagatttat acactttttt cctacagttc acctcagtaa ctgcctttgg     5940

ggttggattt gccaaggtgt tttacggtct tttgaccaca caggttaatt tccccttctc     6000

tcccctccct catgagtcta tccacgcagt tcttaacata cattccaaac tgctgcgggg     6060

tttcctctcc acacccacga ggccaaaccc gcatcattac agtccaactc ttcttagaca     6120

ctaatcactt tctaaaagaa gtgagttctc cagggaagaa aaatcaactt agccagtgaa     6180

aagggttaaa cttaagtcta ttatttgttg ccctcaatca aaagatatgt atagaaaagt     6240

catttaaatt atttatttct acaagctaat tgaatccagg agcagcttta attattaaca     6300

ctaacggaag agaaaagaag tatttccaag ggctcaaatg gaagctgtac tcagtccggt     6360

ggaggcaggg ggaggtaaag tttctcacac tcaagtcgtc ttcatagttt actgtccttt     6420

tccaaacaaa agctaataac gccatacgca tccacacact ccctcctgga tgaacctaag     6480

tctcgtcccc actgtcaccc caaggccagt tatcaaaaac tgttccttct ctgccctcaa     6540

agactgaagc cgcaggccct gttctgcctc tgctcaggaa tctgattgct cttaaagtgc     6600

tcttacaaga ttccgtcgat gtttgctccc tctgtcttat ctctccttcc agtattttca     6660

gacgcacaag ctctgactca ggccacccag cacctggcag ccttcctctg cgtgccagtg     6720

aaatctctcc cagtaggtgc tcaggctctt caccctctcg ttgcagcagc ccctctggcc     6780

cgagattgta ttttctagtc tgctcaagaa cagaggggcc tggcgaggtg gaggaaggga     6840

ggctccctcc ccggggctgg ccgcctcagt gatggtgatg ccaccagctc cagcctgcac     6900

ggatggagct cacttcctac catcacttct gctttcagtc tcctcatagc cttcggcagt     6960

ctcctctgaa aacacactgc ctacgttagt gggaaaggat ggctaagggt gtgatttctt     7020

tttattaggg aggtgggagg gggatgttgg gaggcatggg gggtgattaa attatcattt     7080

ccaaggtgca agtgtttatt tttcaaatct ataagtacat agttccacca ttttggcaca     7140

agacaaaata ctcatgctaa gcaaaggaag agaaagacaa agccagtttt tgttgctttt     7200

ctaaagcaac aaataattct ccaaagaagg ggatgaaaat gctagttcct ttaagcactt     7260

actgactgta aagttggtcc ctgcttaaat tcatacccat agttttgagt cggtatgaca     7320

ccactgcagt gtgagcaagg tgaatccgtg tgccatgcat ggaccacctt gggataccgc     7380

agcaccatca acatccgcct tgctgatgga agccacacac gctgcccagc ccacagcagt     7440

cgcacgcagc cgatgggctc ggactcttag ctggcaggct aggacacaca gtgaacatta     7500

atgtactgtg aatcgttcct gataagtgaa taaaacattg tgaccaaaca atcagcttat     7560

tcacttatca ggaatcgact gttctgctaa tttgctgttg ttgtttttca tctctgttgt     7620

agttcactat ttttgctgtg ttctgttttc tcctctcatg cttgggcaaa tcactgggaa     7680

tattatcttc atgtgaccat gaaacgtttc tattgagtga aaatgatatc ttaacaaaat     7740

ctatgcactt gctatcagga acacaatact ggatgtgtct tatatatatt gaactatata     7800

gtactcgatt tcttaaataa agcttaagaa aggactctgt tgtgtgtaaa gttaatgtga     7860

ttatttttca aagcagtgtt tctaaggggt atttttgttc ttttaagtct tgagtgatac     7920

aggatatttt tcattaaaat tatatcactg gctttatgac ttaatattca ataaattgac     7980

tttggaaaca aaaaaaaaaa aaaaa                                           8005


<210>  917
<211>  8059
<212>  DNA
<213>  homo sapiens

<400>  917
aaaagggcgg tggggcgggg ggcggggcag ggagagggag agaaatccag cagacatcta       60

gctctgcctt tctttcccag ccacagccag ggtagggctg ataaggcgct gatgcgttga      120

tggcagcctt gcagagctag acctgcactt aacttgcagc tgcctcccga gcctccaaga      180

tgtccacgcc ctgggtgaca ggcggcaggg cgctgccccg tgctcccccg gctctgctcg      240

acagcagcac gcagtgagag cctcgccgcc gccgaggagc aactcatgta acggcacagc      300

caacaagatg aacggagctt tggatcactc agaccaacca gacccagatg ccattaagat      360

gtttgtcgga cagatccccc ggtcatggtc ggaaaaggag ctgaaagaac tttttgagcc      420

ttacggagcc gtctaccaga tcaacgtcct ccgggaccgg agtcagaacc ctccgcagag      480

taaaggttgt tgtttcgtaa cattttatac aagaaaagct gcacttgagg cccagaatgc      540

actgcacaat attaaaactt tacctgggat gcatcatccc attcagatga aacctgcaga      600

tagtgaaaag tccaacgctg tggaagacag aaaattgttc ataggaatgg tatcgaagaa      660

atgtaatgag aacgacatca gggtgatgtt ctctccattt ggccagatag aagaatgccg      720

gatcctccgg ggacctgatg ggctgagtcg aggctgtgcg tttgtcacat tttctacaag      780

ggcaatggca cagaatgcaa tcaaagccat gcatcagtct cagaccatgg agggctgctc      840

ttcacctatc gtggtgaagt ttgctgacac tcagaaggac aaagagcaaa ggcgcctcca      900

gcagcagctc gctcagcaga tgcagcagct caacactgcc acctggggga acctgacagg      960

gctgggcgga ctgaccccac agtatctggc gctcctgcag caggccacct cctccagcaa     1020

cctgggtgcg ttcagcggca ttcaacaaat ggcaggcatg aatgctttac agttgcagaa     1080

cctggcgacg ctggctgctg ctgcagctgc ggcccagacc tcagccacca gcaccaatgc     1140

aaaccctctc tctaccacga gcagcgccct gggagccctc acgagtcccg tggctgcttc     1200

aacccccaac tccactgctg gtgcagccat gaactccttg acctctctcg ggactctgca     1260

aggactggct ggagccactg ttggactgaa taatattaat gcactagcag ttgctcaaat     1320

gctctcaggt atggcggctc tgaatggagg acttggcgcc acaggcttga cgaatggcac     1380

ggctggcacc atggacgccc tcacccaggc ctactcagga attcaacagt acgcagccgc     1440

cgcgctgccc actctgtaca gccagagcct gctgcagcag cagagcgctg caggcagcca     1500

gaaggaaggt ccagaggggg caaacctctt tatttaccac cttccacagg aatttggaga     1560

ccaggacatt ctgcagatgt tcatgccttt tggaaatgtt atctctgcta aagtcttcat     1620

tgacaaacag accaatctga gcaagtgctt tggttttgtt agctacgaca atccagtctc     1680

tgcacaagct gctatccaag ctatgaatgg ctttcagatc ggcatgaaac gcttgaaggt     1740

gcagctgaag cgttccaaaa acgacagcaa accttactga tcctaacccc agaggctccc     1800

tgctctcatt ttagctttct taggacatct tcatgcccgt tagttcatcg tttgcctagc     1860

atgtccctgt ggcgtctcaa aaaaaagttt catcgtcccg tcattgtttc tgatgtcttt     1920

ctgacctcac atcatatttg gttctcctac tgacctttga tctagtttga cctttgaaat     1980

ttgcatgtga cctcatctag ctatgaattc tgggaagtca atgtgaaaaa cattgctgca     2040

ttcatgcaag actgaaattt attattagac aaattcatta tagaaaaaac ctgtggcaaa     2100

aacgtttctt tcttattttt tttcttttcc taaaacagac ttgaaagtat tatacaggga     2160

ttggcattct tcccggtcac tggtaacaat agcaatatgt gtccagggac acagaatgtt     2220

ggtttctaac agactacttc caaaaacagt ttgagaaaaa aactgtctga ttttaagtct     2280

ctagaggtct gtaatagttt ttacattttt caggcagtgt aaagtttttt gataaggcca     2340

ttttaggtgg ctcactttct cattaagata tatatataga accacttttt gtagattagt     2400

ataagaaaaa tatttaccct gttttggggc aaatgctacc tatttgtgtc accttttgct     2460

gaactcacag ttagacaatc catggtttaa tgcacatgaa attacctata ttttatactg     2520

tttcaatgta caggagaaag gttactgtaa actgtgttat gttggtgctt ctgtgaatta     2580

agttgtggtt tcatcatgag tcttaatgtt ctttgttgat aagacaagtt tagaattggt     2640

ttacttaata caaaaaaaaa aaaaagaatt tcaaaaaaaa aagttgtttg cttaaaaaaa     2700

atttcatgtg agggaaaaaa aaaaaaccta ttccagaata agttttgtgt tggcttgtga     2760

agcattgatg tcattttttt taattgtgga ctatttagat gtgtttgtgt tcagcaaaat     2820

gtgatctgtt tttttctttt aaagaaaaaa agtgaaaata tatagtgcca aattccaaag     2880

gtacttcctt cctagagctt cagtgtgttt cttgtgagaa gtaatttgat aacatgggta     2940

ttttattatg tgttttgtat aaatccctaa tatttaaaaa aaaaaacaaa acaaaaaaag     3000

gttacaaagt ttgttaactt gctatcctgt ggtcttgttg cctgaaattg ttattgtttg     3060

ttatttctct ctgatgtttt ttgtaagaca ttgtataagt gcccatgtcc cactttttta     3120

accactccgc acatcagtgc tgtgaaggca acctcaccat gtattttctt cataatctat     3180

ggaaacctct aaggtgagaa agttttgaac ttttaaccct ttctacccag agctatctgg     3240

aatgttgatg actttttata ctgtcatgat ttgagtttgt tttggggtgt ttccaatttg     3300

gatttttttc cctgcatcta tcctctaagt tgtttcggtt tgactacttt gttctttggt     3360

taagatccaa aagaaaacag aaaacaattc cacgaggcca atctaaaggg aaaaaatcct     3420

acactacttt tactactttt gattatttct catttttggg aaaagaattc ctaatgtgct     3480

actagaattc cttcttcagt tttaacgagt aattggataa accctgaggg aaaacggagg     3540

tagattcagc acctaacaat cctgtatgct tttgagatca cgtttagtgc tatgtcctag     3600

tctagaatat tttcatatac cttgcagtaa aacgactttg tggcaggaca gtctcttgag     3660

gggttttgtt tctgtttcct aaatactcct aaataatatt tctaatcagc cattatgctg     3720

gggcatctct gatcccagta ggtacctctg aatataccag gtgtctggag ttagaagccc     3780

atagcccttt cccagccttt ttggtttttt taattgaaca catttcatct aagtaaagct     3840

cagttcttta tcacaattta ctgaccaaat acctagcacc agttcctgct gccacttttt     3900

aaagtgccat atgactttct acgaacaggt accttgctgt cttgacaaat cctaatgtca     3960

cgcctacagc cccaacacaa gctccagtct tcctcttcgg catgccctgg aagcttcttg     4020

gcctcagctc cccttccccg ctcagcaccc tgttaggatc agtgtgtgtg gatgggatag     4080

ccctgggatg gaaaggacta gcctctactg atgcaaaaaa acaaaaagca acacaaacgt     4140

ttccttctta tagcacatgc acttccttac aatgacatga tttgtattat cctcacatgt     4200

gtttactact gctggggcct tccttcatcc tctgagggct attttgtact ttctgcagca     4260

atcagcttaa taacaacact tattgcacct gtctctctct gagaacacgg tgtgtctcga     4320

cacgtaccac gtacgtggaa acacaagagc ccaccacttg aatttctaag accatttcat     4380

tctgaaactt cttatcaatt acctaaatct caacgaaaaa caatttactg aagccgactc     4440

ccctccccat ctccctctca acctcaaccc acctgcatgc atctccccca gaggaaacac     4500

tgagggtagg ggacaggagg ctcaggacgc gccctctgaa tcgagtgttt cttcttcaca     4560

agtcaccaag agaggacatg agggggaaag tccttttttg cccttctcca aaaaataacc     4620

ttccacagag acaaactgtc cttctatcca cttttatctt ttaataaata tcaaaaggaa     4680

aaagctgcaa gggtgcaaag ggcctgtgcc agaagaaaac acacacaggg aaaccgcttt     4740

ttttaatcaa ttgtagagaa tagtcatttt taatctaaat tagagaattg tgatacaatg     4800

gcagtcctca aaggcgtaac gagttcatct ttctttcacc ataggggtta tagttggctt     4860

gtgctactct ggaatcattt tactgtttgt ttttattatc ttaagtgcta attaaaaaaa     4920

aaataaaatt ttaaaaaaac ctgtagtttc attacctttt tgaataatgt catacaaaaa     4980

atgtatttgt ttttttgtgc tgtgagaatt gatgtttgta gattaataat cattttgttt     5040

agaattacaa aatagttttt aaatattgtc tgagaaaagc caaagttaat gcaacctagt     5100

ggaaactgta agaccatttg agtattgttt gttttattga tgcatttgga ttttgttgtt     5160

tgatggaatt tgagccaaaa aaaaaatacg caggctttcc tatttctaca actgattgta     5220

cttatgcatt ttgtaccagt ggaacttttt atactggaga ttaaaaaaaa aatggaaatt     5280

tttgtggctt gctctggtgg gcccctgaca atgactgatt tcaagtttga tttcgggttg     5340

attgattgat tgattgatag aaagaaagtt gcttttcttt tgagaattaa aaactttggc     5400

ttgatttctt ttttcccttt gcttatatct agcattagaa ttttgtctta aaataacagc     5460

ggtaagtttc actttttatt ctgtattgtg cagttacaca ataaggtaat tagatttaga     5520

agtactcagt cactttaagt ggataaatgt attagttaaa actttagggt ttgctttttt     5580

gctgtttaga tcaaagtttt ttctgattct tctgtcctca ttgtgaacat aaccgtgtag     5640

ttgaaacagt caaacttatt tttgtaatgt atgttattgt gtgatgcagt tttttgcttc     5700

tgtctccaat attaaaccat tttcctaata cttgtttctc tctctgcgtg ttgtattgtt     5760

ggtagtcatt atatgttggt gatacatctg cacacctcac tgtttcacgt atctgttttt     5820

ttctctatgt tgtgtaaaaa gatacagtcg attccactta agtgaatatc tgatttgggg     5880

aagaggaaac tgcacagcag ccacctttga tttatgtaca accgcccact tgaactcctg     5940

cttccaagat ttatacactt ttttcctaca gttcacctca gtaactgcct ttggggttgg     6000

atttgccaag gtgttttacg gtcttttgac cacacaggtt aatttcccct tctctcccct     6060

ccctcatgag tctatccacg cagttcttaa catacattcc aaactgctgc ggggtttcct     6120

ctccacaccc acgaggccaa acccgcatca ttacagtcca actcttctta gacactaatc     6180

actttctaaa agaagtgagt tctccaggga agaaaaatca acttagccag tgaaaagggt     6240

taaacttaag tctattattt gttgccctca atcaaaagat atgtatagaa aagtcattta     6300

aattatttat ttctacaagc taattgaatc caggagcagc tttaattatt aacactaacg     6360

gaagagaaaa gaagtatttc caagggctca aatggaagct gtactcagtc cggtggaggc     6420

agggggaggt aaagtttctc acactcaagt cgtcttcata gtttactgtc cttttccaaa     6480

caaaagctaa taacgccata cgcatccaca cactccctcc tggatgaacc taagtctcgt     6540

ccccactgtc accccaaggc cagttatcaa aaactgttcc ttctctgccc tcaaagactg     6600

aagccgcagg ccctgttctg cctctgctca ggaatctgat tgctcttaaa gtgctcttac     6660

aagattccgt cgatgtttgc tccctctgtc ttatctctcc ttccagtatt ttcagacgca     6720

caagctctga ctcaggccac ccagcacctg gcagccttcc tctgcgtgcc agtgaaatct     6780

ctcccagtag gtgctcaggc tcttcaccct ctcgttgcag cagcccctct ggcccgagat     6840

tgtattttct agtctgctca agaacagagg ggcctggcga ggtggaggaa gggaggctcc     6900

ctccccgggg ctggccgcct cagtgatggt gatgccacca gctccagcct gcacggatgg     6960

agctcacttc ctaccatcac ttctgctttc agtctcctca tagccttcgg cagtctcctc     7020

tgaaaacaca ctgcctacgt tagtgggaaa ggatggctaa gggtgtgatt tctttttatt     7080

agggaggtgg gagggggatg ttgggaggca tggggggtga ttaaattatc atttccaagg     7140

tgcaagtgtt tatttttcaa atctataagt acatagttcc accattttgg cacaagacaa     7200

aatactcatg ctaagcaaag gaagagaaag acaaagccag tttttgttgc ttttctaaag     7260

caacaaataa ttctccaaag aaggggatga aaatgctagt tcctttaagc acttactgac     7320

tgtaaagttg gtccctgctt aaattcatac ccatagtttt gagtcggtat gacaccactg     7380

cagtgtgagc aaggtgaatc cgtgtgccat gcatggacca ccttgggata ccgcagcacc     7440

atcaacatcc gccttgctga tggaagccac acacgctgcc cagcccacag cagtcgcacg     7500

cagccgatgg gctcggactc ttagctggca ggctaggaca cacagtgaac attaatgtac     7560

tgtgaatcgt tcctgataag tgaataaaac attgtgacca aacaatcagc ttattcactt     7620

atcaggaatc gactgttctg ctaatttgct gttgttgttt ttcatctctg ttgtagttca     7680

ctatttttgc tgtgttctgt tttctcctct catgcttggg caaatcactg ggaatattat     7740

cttcatgtga ccatgaaacg tttctattga gtgaaaatga tatcttaaca aaatctatgc     7800

acttgctatc aggaacacaa tactggatgt gtcttatata tattgaacta tatagtactc     7860

gatttcttaa ataaagctta agaaaggact ctgttgtgtg taaagttaat gtgattattt     7920

ttcaaagcag tgtttctaag gggtattttt gttcttttaa gtcttgagtg atacaggata     7980

tttttcatta aaattatatc actggcttta tgacttaata ttcaataaat tgactttgga     8040

aacaaaaaaa aaaaaaaaa                                                  8059


<210>  918
<211>  2707
<212>  DNA
<213>  homo sapiens

<400>  918
gggctcgagg cgttcggctg aggaagggag cgcacgccgg cggcgcggag gccggctctg       60

cgcttcgggc cgccccctcc ccccaccccg ctcacacccg gcacttactt cggctgtctc      120

cgctgccctc cagcggagac gcagctcctc aggcgcccgg cggtatttgt tgggtcggcg      180

gcgtcaggga ttcgcagtgg cctgtggtcg gcgtcgtccg gccactggtg cgcccccgcg      240

gcaggcagag ctcacgctcc tgtcccccgg ctggtccggg gtctgggcgc cgcgtcgacg      300

gcggctccgc aggacgcgca gaccgggccg cagcccattc cccgagcgga ctgcattatg      360

aggcacctgc cttacttctg ccggggtcaa gtggtgcggg gcttcggccg cggctccaag      420

cagctgggca tccccacagc taattttcct gagcaagtgg tagataatct tccagctgat      480

atatccactg gtatttacta tggttgggcc agtgttggaa gtggagatgt ccataagatg      540

gtggtgagca taggatggaa cccatattac aagaatacga agaagtctat ggaaacacat      600

atcatgcata ccttcaaaga ggacttctat ggggaaatcc tcaatgtggc cattgttggc      660

tacctgagac cagaaaagaa ctttgattct ttagagtcac ttatttcagc aattcaaggt      720

gatattgaag aagctaagaa acgactagag ttaccagaac atttgaaaat caaagaagac      780

aatttcttcc aggtttctaa aagcaaaata atgaatggcc actgatgaaa aattgtatta      840

tttattcatt cactgttttc tagtgtttct gtgtttatta ctgttcagca tcatcttggt      900

tatatactga aaatcaaaca ctttactaca gttgtgaatt agtttaaacc gtacaatgtt      960

gttatcatat catgcttcaa ctattaaatt aagcccatca tatcatagca ctaaaaagat     1020

tgagttaaaa ataagattta aaaaatatat attgattaaa atgtaccact agaaaggtat     1080

tacatgtgta taagtatggg taaaaaggca agtcactagt ttgagatgaa aactaaaatt     1140

ttcatggtaa aatgccagca tgtatgtact tgtgtagtgt gtacttctaa acagagaagg     1200

cttataaaag taaatgcatt aaggccaagt gcagtggctc acaccggtaa tcccagcact     1260

ttgggaggcc gaggtgggag gattgcttga gctcatgagt tcaagaccag cctgggcaac     1320

atagcgagac tccatctcta taaataaaaa aaaaggaaat gcattaaata gaaggttgat     1380

agtttatcat aaacctgcgg ggaagaaact cagactttct atttttgata ttttgtgcat     1440

taatacatta caaacatgaa gatgtttgta aagttttgtt ttagtcattt tctttgcagt     1500

cacatcattg taccaccttc attattgtat agagctgctt caattctgag tcctctggac     1560

ttcccctgcc tatctgtttg ttgttgttgt tgaagacagt aaaataagtg ttttcaaatc     1620

tatatgtctc ctttttgttg gataatgttt cttcttttta atggtaaata ttcttgttct     1680

tcaacatttt tctttggttc ttttttcctt ttttaggaaa aacaaaacaa cagacttcat     1740

ccttaggttt tctcaagatt taagtgaaca catttacaca tatcaatttc ttaaagaaca     1800

caaaatgttt cctccctagc aaaactattt aagagccaat taaactatga aatagttata     1860

aaattatttt taatatttaa ggccttgaaa ttatattcca aggcaaatct aaatgggtgt     1920

agttgtatat gcacgatgta atttaatgct aaagagtact tacagcttga gggaaaagca     1980

taaagtttta gttaaatagc cttcatactg tggatttttc ctcctactaa ctaatatgtg     2040

ggaaattaag attacagatg ctttgggccc cctcaaacag tacattgcta cagttcactg     2100

tagcaacaga tttggtggtg atggggggat agaggtagaa gcagatagaa ggtaatttta     2160

aagttaattt attatgaatc attttcccct aatctgcata aatgaattag aactgatttt     2220

aataaaaata ttctgtgtaa aaagtactca gaaaaacatc taaagctgtt ggagaagagg     2280

gactcatata aatagttgga ttgcgttttg ctttttattt ctttataaaa atatgtcaaa     2340

aacagttttt aattttagaa atcttatact tgaaagaaac ctcaattatc agtggcttta     2400

tgaagtaaag ttaaaaacaa acataggaaa tgtgaaaata tttgtgtttg ttttgtctga     2460

ctaacttgct gctaaatgct atctttaggt gtgtgaaagt tctttgatat gttattgtcc     2520

ttttacatct tgttaaatag ccattgcttt tgagaatcag atagtgtgtt gtttaggggt     2580

taattgtgtc tatatctttc aaaaactttt atattatgta ttataagaag ttacagtagt     2640

accattttga ttagtctgaa tgttttcagg ccttgaaata aattttgact aagtgatatt     2700

ttttctt                                                               2707


<210>  919
<211>  1940
<212>  DNA
<213>  homo sapiens

<400>  919
agggcccgga gccggcgagt gctcccggga actctgcctg cgcggcggca gcgaccggag       60

gccaggccca gcacgccgga gctggcctgc tggggagggg cgggaggcgc gcgcgggagg      120

gtccgcccgg ccagggcccc gggcgctcgc agaggccggc cgcgctccca gcccgcccgg      180

agcccatgcc cggcggctgg ccagtgctgc ggcagaaggg ggggcccggc tctgcatggc      240

cccggctgct gacatgactt ctttgccact cggtgtcaaa gtggaggact ccgccttcgg      300

caagccggcg gggggaggcg cgggccaggc ccccagcgcc gccgcggcca cggcagccgc      360

catgggcgcg gacgaggagg gggccaagcc caaagtgtcc ccttcgctcc tgcccttcag      420

cgtggaggcg ctcatggccg accacaggaa gccgggggcc aaggagagcg ccctggcgcc      480

ctccgagggc gtgcaggcgg cgggtggctc ggcgcagcca ctgggcgtcc cgccggggtc      540

gctgggagcc ccggacgcgc cctcttcgcc gcggccgctc ggccatttct cggtgggggg      600

actcctcaag ctgccagaag atgcgctcgt caaagccgag agccccgaga agcccgagag      660

gaccccgtgg atgcagagcc cccgcttctc cccgccgccg gccaggcggc tgagcccccc      720

agcctgcacc ctccgcaaac acaagacgaa ccgtaagccg cggacgccct tcaccaccgc      780

gcagctgctg gcgctggagc gcaagttccg ccagaagcag tacctgtcca tcgccgagcg      840

cgcggagttc tccagctcgc tcagcctcac tgagacgcag gtgaagatat ggttccagaa      900

ccgccgcgcc aaggcaaaga gactacaaga ggcagagctg gagaagctga agatggccgc      960

caagcccatg ctgccaccgg ctgccttcgg cctctccttc cctctcggcg gccccgcagc     1020

tgtagcggcc gcggcgggtg cctcgctcta cggtgcctct ggccccttcc agcgcgccgc     1080

gctgcctgtg gcgcccgtgg gactctacac ggcccatgtg ggctacagca tgtaccacct     1140

gacatagagg gtcccaggtc gcccacctgt gggccagccg attcctccag ccctggtgct     1200

gtacccccga cgtgctcccc tgctcggcac cgccagccgc cttcccttta accctcacac     1260

tgctccagtt tcacctcttt gctccctgag ttcactctcc gaagtctgat ccctgccaaa     1320

aagtggctgg aagagtccct tagtactctt ctagcattta gatctacact ctcgagttaa     1380

agatggggaa actgagggca gagaggttaa cagatttatc taaggtcccc agcagaattg     1440

acagttgaac agagctagag gccatgtctc ctgcatagct tttccctgtc ctgacaccag     1500

gcaagaaaag cgcagagaaa tcggtgtctg acgattttgg aaatgagaac aatctcaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaaaagag aaaaaaaaga ctagccagcc     1620

aggaagatga atcctagctt cttccattgg aaaatttaag acaagttcaa caacaaaaca     1680

tttgctctgg ggggcaggga aaacacagat gtgttgcaaa ggtaggttga agggacctct     1740

ctcttaccag taccagaaac acaattgtaa aattaaaaaa aaaaaaaaac tctttctatt     1800

taacagtaca tttgtgtggc tctcaaacat ccctttggaa gggattgtgt gtactatgta     1860

atatactgta tatttgaaat tttattatca tttatattat agctatattt gttaaataaa     1920

ttaattttaa gctacaaaaa                                                 1940


<210>  920
<211>  1327
<212>  DNA
<213>  homo sapiens

<400>  920
ttggtttggg ccaggtggac tggaaggggc ggaggtaacc agaagcggct agtggcggct       60

gcctgcgtcc ccaaccccct ccgcgcagcg ctcgcgacac gcgtgccagg agtgggagcg      120

agcggcgggg ccagctgcgt tctgagcctg ggcgcagctg ccatctgctc tgggaagcac      180

cagggtgtcc ccgccgccct cagctcgaag tcagccacca tggaggcgca ggcacaaggt      240

ttgttggaga ctgaaccgtt gcaaggaaca gacgaagatg cagtagccag tgctgacttc      300

tctagcatgc tctctgagga ggaaaaggaa gagttaaaag cagagttagt tcagctagaa      360

gacgaaatta caacactacg acaagttttg tcagcgaaag aaaggcatct agttgagata      420

aaacaaaaac tcggcatgaa cctgatgaat gaattaaaac agaacttcag caaaagctgg      480

catgacatgc agactaccac tgcctacaag aaaacacatg aaaccctgag tcacgcaggg      540

caaaaggcaa ctgcagcttt cagcaacgtt ggaacggcca tcagcaagaa gttcggagac      600

atgagttact ccattcgcca ttccataagt atgcctgcta tgagacgaaa gtaggcggta      660

cgaaccctaa tggaggcagt tttgaggagg tcctcagctc cacggcccat gccagtgccc      720

agagcttggc aggaggctcc cggcggacca aggaggagga gctgcagtgc taagtccagc      780

cagcgtgcag ctgcatccag aaaccggcca ctacccagcc catctctgcc tgtgcttatc      840

cagataagaa gaccaaaatc ccgctgggaa aaacccaggc cttgacattg ttattcaaat      900

ggcccctcca gaaagtttaa tgatttccat ttgtatttgt gttgatgatg gaccacttga      960

ccatcacatt tcagtattca tagatgactg tcacatttta aaatgttccc acttgagcag     1020

gtacacaact ggtcataatt cctgtctgtg taattcgatg tatatttttc caaacatgta     1080

gctattgttt gctttgattt ttgcttggcc tcctttatga tgtgcatgtc cttgaaggct     1140

gaatgaacag tccctttcag ttcagcagat caacaggatg gagctcttca tgactgtctc     1200

cagcaatagg atgatttact ataaatttca tccaactact tgtgatctct ctcacctaca     1260

tcaattatgt atgttaattt cagcaattaa aagaattgat tttaatgaca aaaaaaaaaa     1320

aaaaaaa                                                               1327


<210>  921
<211>  2891
<212>  DNA
<213>  homo sapiens

<400>  921
aaaaaaagga aaaggaaaaa gcccatgaaa tgctactagc tacttcagac ctctttcagc       60

ctaagaggaa agcctgttag cagagcacgg accagtgtct ccggagaatg ctattctcct      120

acatttccga acaggttatc aacgcacaga tcgatcactg cctctgtccc atcgctccct      180

gaagtagctc tgactccggt tccttgaaag gggcgtgtac agaagtaaag atggagcctg      240

caggggagcg ctttcccgaa caaaggcaag tcctgattct ccttctttta ctggaagtga      300

ctctggcagg ctgggaaccc cgtcgctatt ctgtgatgga ggaaacagag agaggttctt      360

ttgtagccaa cctggccaat gacctagggc tgggagtggg ggagctagcc gagcggggag      420

cccgggtagt ttctgaggat aacgaacaag gcttgcagct tgatctgcag accgggcagt      480

tgatattaaa tgagaagctg gaccgggaga agctgtgtgg ccctactgag ccctgtataa      540

tgcatttcca agtgttactg aaaaaacctt tggaagtatt tcgagctgaa ctactagtga      600

cagacataaa cgatcattct cctgagtttc ctgaaagaga aatgaccctg aaaatcccag      660

aaactagctc ccttgggact gtgtttcctc tgaaaaaagc tcgggacttg gacgtgggca      720

gcaataatgt tcaaaactac aatatttctc ccaattctca tttccatgtt tccactcgca      780

cccgagggga tggcaggaaa tacccagagc tggtgctgga cacagaactg gatcgcgagg      840

agcaggccga gctcagatta accttgacag cggtggacgg tggctctcca ccccgatctg      900

gcaccgtcca gatcctcatc ttggtcttgg acgccaatga caatgccccg gagtttgtgc      960

aggcgctcta cgaggtgcag gtcccagaga acagcccagt aggctcccta gttgtcaagg     1020

tctctgctag ggatttagac actgggacaa atggagagat atcatactcc ctttattaca     1080

gctctcagga gatagacaaa ccttttgagc taagcagcct ttcaggagaa attcgactaa     1140

ttaaaaaact agattttgag acaatgtctt cgtatgatct agatatagag gcatctgatg     1200

gcgggggact ttctggaaaa tgctctgtct ctgttaaggt gctggatgtt aacgataact     1260

tcccggaact aagtatttca tcacttacca gccctattcc cgagaattct ccagagacag     1320

aagtggccct gtttaggatt agagaccgag actctgggga aaatggaaaa atgatttgct     1380

caattcagga tgatgttcct tttaagctaa aaccttctgt tgagaatttc tacaggctgg     1440

taacagaagg ggcgctggac agagagacca gagccgagta caacatcacc atcaccatca     1500

cagacttggg gactccaagg ctgaaaaccg agcagagcat aaccgtgctg gtgtcggacg     1560

tcaatgacaa cgcccccgcc ttcacccaaa cctcctacac cctgttcgtc cgcgagaaca     1620

acagccccgc cctgcacatc ggcagtgtca gcgccacaga cagagactcg ggcaccaacg     1680

cccaggtcac ctactcgctg ctgccgcccc gggacccgca cctgcccctc acctccctgg     1740

tctccattaa cacggacaac ggccacctgt tcgctctcca gtcgctggac tacgaggccc     1800

tgcaggcttt cgagttccgc gtgggcgcca cagaccgcgg cttcccggcg ctgagcagcg     1860

aggcgctggt gcgagtgctg gtgctggacg ccaacgacaa ctcgcccttc gtgctgtacc     1920

cgctgcagaa cggctccgcg ccctgcaccg agctggtgcc ccgggcggcc gagccgggct     1980

acctggtgac caaggtggtg gcggtggacg gcgactcggg ccagaacgcc tggctgtcgt     2040

accagctgct caaggccacg gagcccgggc tgttcggcgt gtgggcgcac aatggcgagg     2100

tgcgcaccgc caggctgctg agcgagcgcg acgtggccaa gcacaggcta gtggtgctgg     2160

tcaaggacaa tggcgagcct ccgcgctcgg ccaccgccac gctgcaagtg ctcctggtgg     2220

acggcttctc tcagccctac ctgccgctcc cagaggcggc cccggcccaa gcccaggccg     2280

actcgcttac cgtctacctg gtggtggcat tggcctcggt gtcttcgctc ttcctcttct     2340

cggtgttcct gttcgtggca gtgcggctgt gcaggaggag cagggcggcc tcagtgggtc     2400

gctgctcggt gcccgagggc ccctttccag ggcatctggt ggacgtgagc ggcaccggga     2460

ccctttccca gagctaccag tacgaggtgt gtctgacggg aggctctgaa agtaatgatt     2520

tcaagttctt gaagcctata ttcccaaata ttgtaagcca ggactctagg aggaaatcag     2580

aatttctaga ataatgtagg tatctgtagc tttccgaccg tctgttaatt ttgtcttcct     2640

cacttttcac cttagttttt tttaaccctt tagtaatctt gaattctact tttttttaaa     2700

tttctactgt tgtctttagt aatgttactc atttcctttg tctgattgtt agttttcaaa     2760

ttattgtatt attataaata ttttatatca ggaaagttca tatttctgaa taaattaata     2820

gtattcattc ctgaagggtg atatgaaagt taaccccacc taataaacat aactctaatt     2880

ctgaaaaaaa a                                                          2891


<210>  922
<211>  5653
<212>  DNA
<213>  homo sapiens

<400>  922
gacaaagaga actaatgctt tgtgctgatt catatttgaa tcgaggcatt gggaaccctg       60

tatgccttgt ttgtggaaag aaccagtgac accatcactg agcttcctaa aagttcgaag      120

aagttagagg actatacact ttcttttgaa cttttataat aaatatttgc tctggttttt      180

ggaacccagg gctgttagag gggtgagtga caagtcttac aagtggcctt attccaactc      240

cagaaattgc ccaacggaac tttgagatta tatgcaatcg aaagtgacag gaaacatgcc      300

aactcaatcc ctcttaatgt acatggatgg gccagaagtg attggcagct ctcttggcag      360

tccgatggag atggaggatg ccttgtcaat gaaagggacc gctgttgttc cattccgagc      420

tacacaagaa aaaaatgtca tccaaatcga ggggtatatg cccttggatt gcatgttctg      480

cagccagacc ttcacacatt cagaagacct taataaacat gtcttaatgc aacaccggcc      540

taccctctgt gaaccagcag ttcttcgggt tgaagcagag tatctcagtc cgcttgataa      600

aagtcaagtg cgaacagaac ctcccaagga aaagaattgc aaggaaaatg aatttagctg      660

tgaggtatgt gggcagacat ttagagtcgc ttttgatgtt gagatccaca tgagaacaca      720

caaagattct ttcacttacg ggtgtaacat gtgcggaaga agattcaagg agccttggtt      780

tcttaaaaat cacatgcgga cacataatgg caaatcgggg gccagaagca aactgcagca      840

aggcttggag agtagtccag caacgatcaa cgaggtcgtc caggtgcacg cggccgagag      900

catctcctct ccttacaaaa tctgcatggt ttgtggcttc ctatttccaa ataaagaaag      960

tctaattgag caccgcaagg tgcacaccaa aaaaactgct ttcggtacca gcagcgcgca     1020

gacagactct ccacaaggag gaatgccgtc ctcgagggag gacttcctgc agttgttcaa     1080

cttgagacca aaatctcacc ctgaaacggg gaagaagcct gtcagatgca tccctcagct     1140

cgatccgttc accaccttcc aggcttggca gctggctacc aaaggaaaag ttgccatttg     1200

ccaagaagtg aaggaatcgg ggcaagaagg gagcaccgac aacgacgatt cgagttccga     1260

gaaggagctt ggagaaacaa ataagggcag ttgtgcaggc ctctcgcaag agaaagagaa     1320

gtgcaaacac tcccacggcg aagcgccctc cgtggacgcg gatcccaagt tacccagtag     1380

caaggagaag cccactcact gctccgagtg cggcaaagct ttcagaacct accaccagct     1440

ggtcttgcac tccagggtcc acaagaagga ccggagggcc ggcgcggagt cgcccaccat     1500

gtctgtggac gggaggcagc cggggacgtg ttctcctgac ctcgccgccc ctctggatga     1560

aaatggagcc gtggatcgag gggaaggtgg ttctgaagac ggatctgagg atgggcttcc     1620

cgaaggaatc catctggata aaaatgatga tggaggaaaa ataaaacatc ttacatcttc     1680

aagagagtgt agttattgtg gaaagttttt ccgttcaaat tattacctca atattcatct     1740

cagaacgcat acaggtgaaa aaccatacaa atgtgaattt tgtgaatatg ctgcagccca     1800

gaagacatct ctgaggtatc acttggagag acatcacaag gaaaaacaaa ccgatgttgc     1860

tgctgaagtc aagaacgatg gtaaaaatca ggacactgaa gatgcactat taaccgctga     1920

cagtgcgcaa accaaaaatt tgaaaagatt ttttgatggt gccaaagatg ttacaggcag     1980

tccacctgca aagcagctta aggagatgcc ttctgttttt cagaatgttc tgggcagcgc     2040

tgtcctctca ccagcacaca aagatactca ggatttccat aaaaatgcag ctgatgacag     2100

tgctgataaa gtgaataaaa accctacccc tgcttacctg gacctgttaa aaaagagatc     2160

agcagttgaa actcaggcaa ataacctcat ctgtagaacc aaggcggatg ttactcctcc     2220

tccggatggc agtaccaccc ataaccttga agttagcccc aaagagaagc aaacggagac     2280

cgcagctgac tgcagataca ggccaagtgt ggattgtcac gaaaaacctt taaatttatc     2340

cgtgggggct cttcacaatt gcccggcaat ttctttgagt aaaagtttga ttccaagtat     2400

cacctgtcca ttttgtacct tcaagacatt ttatccagaa gttttaatga tgcaccagag     2460

actggagcat aaatacaatc ctgacgttca taaaaactgt cgaaacaagt ccttgcttag     2520

aagtcgacgt accggatgcc cgccagcgtt gctgggaaaa gatgtgcctc ccctctctag     2580

tttctgtaaa cccaagccca agtctgcttt cccggcgcag tccaaatccc tgccatctgc     2640

gaaggggaag cagagccctc ctgggccagg caaggcccct ctgacttcag ggatagactc     2700

tagcacttta gccccaagta acctgaagtc ccacagacca cagcagaatg tgggggtcca     2760

aggggccgcc accaggcaac agcaatctga gatgtttcct aaaaccagtg tttcccctgc     2820

accggataag acaaaaagac ccgagacaaa attgaaacct cttccagtag ctccttctca     2880

gcccaccctc ggcagcagta acatcaatgg ttccatcgac taccccgcca agaacgacag     2940

cccgtgggca cctccgggaa gagactattt ctgtaatcgg agtgccagca atactgcagc     3000

agaatttggt gagccccttc caaaaagact gaagtccagc gtggttgccc ttgacgttga     3060

ccagcccggg gccaattaca gaagaggcta tgaccttccc aagtaccata tggtcagagg     3120

catcacatca ctgttaccgc aggactgtgt gtatccgtcg caggcgctgc ctcccaaacc     3180

aaggttcctg agctccagcg aggtcgattc tccaaatgtg ctgactgttc agaagcccta     3240

tggtggctcc gggccacttt acacttgtgt gcctgctggt agtccagcat ccagctcgac     3300

gttagaagga aaaaggcctg tgtcatatca acacttatct aacagcatgg cacaaaagag     3360

aaactatgag aattttattg ggaatgcaca ttatcgacca aatgacaaaa aaacttgatt     3420

cactaattag ggggaaaaaa ggtcttggtg gatgtcagtg cttactcccc atgaaattaa     3480

attttacttc atcctttgag aagcgaatgg tgaaagctac tgaaataagc tgtgattgta     3540

ctgtacataa aacatatgag gaatctgcaa ggaacactac agttgtgtaa agttgttctg     3600

ttaacttttg taccaaatag caatacaaac tagttggaac agttggaact tacatacatg     3660

gggactggaa atctctattt tgtccctgaa taatattttt cttagaattg accaaataag     3720

aagtggaatt tttgcatact tgagcgctgc tgaaaagaaa tcatttgggt tgggtggggc     3780

gggatggggg aaaagtatat aatgcttgca cctcaggtaa aaatctgtaa atatctaagt     3840

tgtaaacctg cttgttcaaa tactgtgtgt attccttttc tctaatgcag ctcatcactt     3900

ggagcagttt ctgctattgt gctctttcat ttaaaatgta tgtttttttt tttttaaact     3960

gtcaatgatt ttgtattatg ttgaatccac ccaaatctat tgttgtctta aaattgttaa     4020

tggaagtatt gaccctctat gatatgtgct gcagatatcg aggtcagcca ttcggaagct     4080

ggcagcattt tatcgcaact ttgagcatct cagatgggga aggcaccttc ttcctcgcct     4140

ctccagattg tcctggaacc tccaggatcc ttgactgagg gcgttgggat ggcttgtagg     4200

atttttaaga gagtgtgtct acagacaagc attttctctg tagagcagcc acacgttgta     4260

taaacataaa ctgtatgtgc agttatttaa atttgtttct gtcaaattaa tcatttttgt     4320

tggacgattc agtggcgggg gggttttgcc taaattagta tataaaaaca aaaatgctaa     4380

attatatctg tgaattgcag gtattgggga acagttttaa gggaaatttt ggggggaaca     4440

ttttaggttt gtatttggta gtcttaatgt atctggcatt tgggtgaact gtggacatac     4500

tagagttgat tatagacaca ttgattttga ataaggaact gctggccgag cccgctggga     4560

gtctagaaag agaaaatctg tttctagacc tcagttattt tcccattttt ggttgttttg     4620

aagcagtaac atttttctca gtgcacatgc aatttgggtt ttagagaaga tggccaccag     4680

ctggcttcct agatatttta aacttttgtt ctttaatatg ctgtccatgg ctgagtttat     4740

tagtacatgg gcttagtgac cacaaaatat tttattaaga aactgtttca aaaataaatt     4800

tgcactgttc atttttctgg cctcgctgtt ctccatagag caagggtaat cctagaaaaa     4860

attttttttt tttaaattat gcaacgtaag atgtcctcct tgatagaagt cttagctcct     4920

gtgttacaag ggagaactca tttgagatca gtctgttggc attgcaatga agtgctttgt     4980

atcaggaaag tgtacactat tgaccttttt tcctgttcac aagctgagcc atatgtacat     5040

aatctagatt ttgttttcat agttttgcac ttttatagcc tatttttgaa gattaacaca     5100

tttgcaagat gattgactca atctttgcct aatccaatga gtgttacaga gagcttgctg     5160

tgactagaac cataaatctt aaagggggta tgtgataata gagggctgga atttaaacct     5220

gtatttaaaa aaaagaatca ccaaatctat ttgaaaacaa gtcgatttgt attatgctgg     5280

aattttttgg gctttcagat ttctcttttt aaccacattt ctgaatgtat aaaaatacca     5340

attattttcc tacagccctt tgtacttcaa aatatgtttt tgtgtccatc agtattaact     5400

attggtatac tactggtttt atattttttt ttctttgaga caacagtaca tataatagag     5460

gtacaattcg ttggattttt gtttatgtat ttatttcatt ccagtttgat ttattttaat     5520

tgttgatact taagttgtcg aacagtagac attacttgtt ttatttatga tatatttcag     5580

cttaaagtta tgttattata tgtggaagtg taaatataga tttggtgttt tgcaaaaaaa     5640

aaaaaaaaaa aaa                                                        5653


<210>  923
<211>  3914
<212>  DNA
<213>  homo sapiens

<400>  923
agtggcgtcc gttgtaagtg ctatgacaac agggcgaaga tggctcagag ttaggctgga       60

gaggggaggt gtcccttccg ctgcggccgt cgggtttctg ctacatccca ttcaccgcct      120

cctccatcct ttcctcctcg gtgtgagcag caggacttgc atttgttctc gcctgcctag      180

tgtcttccaa gggatagatg ccgtttcctc tgctggtctc tgggggtgac ggggggcgca      240

ggggagcttc ttgggggaat cactccaact ctgtggagct ggtggtgctg cctggtgggg      300

ctctctcttt gcccgggacg tggaacaact ttcagctgga ggacgagagg gaatagtgaa      360

gctaaaggtt gcttttctct gcaccgtccg ttcttgctcc ctctgctcca tcactgggac      420

cttgtcaggc gttcataaag caaaatttgc cgaacgaggg ttcgcagaaa ggtggggcag      480

agctcatctg acgtggcatc agtgtgaaag aaaatgtctt tatttaaagc ccgtgattgg      540

tggtctacta ttctgggaga taaagaagaa tttgatcaag gctgtttgtg tctggctaat      600

gttgacaata gtggaaatgg acaagataaa ataattgtgg gtagctttat gggataccta      660

aggatcttta gcccccatcc tgcaaaaaca ggagatggag ctcaagccga agatttgctt      720

ctagaagtgg atctacgaga tccagtactt caagtggaag taggaaagtt tgtttcaggt      780

accgaaatgc tacatttggc tgtgttacat tctagaaaac tttgtgtcta ctctgtctca      840

ggaaccttgg gtaatgtgga acatgggaac caatgtcaga tgaaattgat gtatgaacat      900

aatcttcaga gaacagcctg caatatgacc tatggatcat ttggtggtgt aaaaggtcga      960

gatttaattt gcatccagtc tatggatggg atgctgatgg tatttgagca ggagagctat     1020

gcttttggaa gatttctccc tggctttctt ctgcctggtc ctcttgccta cagttcccgt     1080

acagattcct tccttactgt ctcttcctgc caacaagtgg aaagttataa gtaccaggta     1140

cttgcttttg caacagatgc agataaaagg caggagactg aacagcaaaa acttggttct     1200

ggaaaaagac tagttgtgga ttggactcta aatattggag agcaagccct tgacatatgt     1260

attgtctctt tcaatcagtc ggcatcctct gtttttgttc ttggtgagag aaactttttt     1320

tgccttaagg ataatggaca aattcgattc atgaagaagc ttgattggag cccaagttgt     1380

tttctgccat attgctcagt ttctgaagga acaataaata ctttgattgg aaatcataat     1440

aacatgctgc atatttatca agatgtgaca ctgaagtggg ccacccaact tccccacatt     1500

cctgtagcag taagagtggg ctgtttgcat gatttaaagg gagtgatagt cactctgagt     1560

gatgatggtc acttgcagtg ttcatacctg gggacagatc cttctctgtt ccaagctcca     1620

aacgttcaat ctcgagaact aaactatgat gaacttgatg tagaaatgaa agaacttcag     1680

aaaatcatca aagatgttaa caaatcacaa ggtgtttggc ccatgactga gagagaagat     1740

gacttgaacg tttctgtcgt ggtttctcct aactttgatt cagtttctca agcgaccgat     1800

gttgaggtgg gaactgacct tgtcccttct gtcacggtga aggtcacact gcagaacaga     1860

gtgatattgc aaaaagccaa attatcagtc tacgtgcaac caccattaga attgacttgt     1920

gatcagttca cctttgaatt tatgaatcga aatcctgatg gcattccgcg agttatccaa     1980

tgtaaattta gacttcccct aaagttaatt tgcctaccag gtcagccttc aaaaactgca     2040

agccacaaaa ttactattga taccaacaaa tctccagtca gtcttcttag tctcttccca     2100

ggttttgcca gtcagtcaga tgatgatcag gtgaatgtaa tgggttttca cttcttagga     2160

ggtgctcgaa ttactgttct tgcttccaaa acttctcaac gatatcgcat tcagagtgaa     2220

caatttgaag atctttggct cataaccaat gagcttattc ttcgccttca agaatatttt     2280

gaaaaacagg gagtcaaaga ttttgcatgt tctttttcgg gatctatacc ccttcaagaa     2340

tattttgagt tgattgatca tcattttgag ctacggataa atggtgaaaa attagaagaa     2400

ctcttatctg agagagctgt acaatttcgg gccattcaac gccggctact agcaagattc     2460

aaagataaaa ctcctgcccc tcttcaacac ctggacacct tgttagatgg aacctacaag     2520

caggtaattg ctctagcaga tgcagtggag gaaaaccaag gcaatctgtt ccagtcattc     2580

accaggctga agagtgccac ccatttggtg attctgctga tcgcgctgtg gcagaagctt     2640

agtgctgacc aggttgctat tctggaagcg gcatttctgc cgctacaaga agacactcaa     2700

gaattgggct gggaagaaac ggtggatgcc gccatttccc acctgttgaa gacttgcctg     2760

tcgaagagtt ctaaggagca ggctttgaac ctcaacagcc agctgaacat acccaaagac     2820

acaagccaac tgaagaaaca tatcaccttg ctctgcgata gattatccaa aggtggccgt     2880

ctctgcctaa gtaccgatgc agcagcccca cagaccatgg tcatgccagg tggttgtact     2940

acaatcccag agtcagacct agaagaaaga tcagtagaac aagactctac agaactgttt     3000

accaaccaca gacatctcac tgcagagaca cccaggcctg aagtttcacc cctccaagga     3060

gtctcggaat aattcaagta gagttgtttg gttgagagga acatccccat ctcaaggccg     3120

aacctgtgtg aacctcatgc caagcacaga tatagggctg gcgcaggtgc ttcctaaagc     3180

tcaccttcct ggagatgaca tgcatagaaa gaggggttgg gactttttac ttcactagga     3240

gaacttgtaa caccatgggg aagtcagctg aaacttgtct tgttttgcca ggaaaggaag     3300

tagttgcctt tggtcatcca tctgctaata gtcacagaat acagtgaaat gacatagttt     3360

tgggttagat tttataatgc aaagattcag atccaaaata atttcatacc ccattttttc     3420

acagaattct tatatagtaa atgtatcaag tttaataaag catctcattg tcaaataata     3480

tcttggattt tatttataat tagagggatt tatgagtgat tgctctacat tatttcttca     3540

aaggaaagga aaggaattga agactttgct actctctggt aagacttgaa tgtgattatt     3600

ttataaataa aagaaccact atgaaacttt catgtgattt gttctattaa gctaaacgtg     3660

gaagaaggga agttttctag tattgtatga aaatgtttaa atattttcaa ggaagctagt     3720

acattaacat ccccttttca ttaccccatt gggtggcacc ttttaaaaat ccaggttatt     3780

aaaggattca cactttatta cagttaaaat ttaaggtttt tatgtgtaag aagtgaaaga     3840

aactttgcta atttcaagtt cgaattacag ttgtgagatt gatttattta aataaaaata     3900

tgcctttgcc agtt                                                       3914


<210>  924
<211>  4772
<212>  DNA
<213>  homo sapiens

<400>  924
cggcgtcgcc gcaagagcgc gagaggcgcg gcgggaggag ccggcggcgc gcgcctccct       60

gggcccggac tcggccgcct cccgccgcct cccgcgcggc catggactga gcgccgccgg      120

ccaggccgcg gggatggggc cgccgctccc gctgctgctg ctgctactgc tgctgctgcc      180

gccacgcgtc ctgcctgccg ccccttcgtc cgtcccccgc ggccggcagc tcccggggcg      240

tctgggctgc ctgctcgagg agggcctctg cggagcgtcc gaggcctgtg tgaacgatgg      300

agtgtttgga aggtgccaga aggttccggc aatggacttt taccgctacg aggtgtcgcc      360

cgtggccctg cagcgcctgc gcgtggcgtt gcagaagctt tccggcacag gtttcacgtg      420

gcaggatgac tatactcagt atgtgatgga ccaggaactt gcagacctcc cgaaaaccta      480

cctgaggcgt cctgaagcat ccagcccagc caggccctca aaacacagcg ttggcagcga      540

gaggaggtac agtcgggagg gcggtgctgc cctggccaac gccctccgac gccacctgcc      600

cttcctggag gccctgtccc aggccccagc ctcagacgtg ctcgccagga cccatacggc      660

gcaggacaga ccccccgctg agggtgatga ccgcttctcc gagagcatcc tgacctatgt      720

ggcccacacg tctgcgctga cctaccctcc cgggtcccgg acccagctcc gcgaggacct      780

cctgccgcgg accctcggcc agctccagcc agatgagctc agccctaagg tggacagtgg      840

tgtggacaga caccatctga tggcggccct cagtgcctat gctgcccaga ggcccccagc      900

tccccccggg gagggcagcc tggagccaca gtaccttctg cgtgcaccct caagaatgcc      960

caggcctttg ctggcaccag ccgcccccca gaagtggcct tcacctctgg gagattccga     1020

agacccctcc agcacaggcg atggagcacg gattcatacc ctcctgaagg acctgcagag     1080

gcagccggct gaggtgaggg gcctgagtgg cctggagctg gacggcatgg ctgagctgat     1140

ggctggcctg atgcaaggcg tggaccatgg agtagctcga ggcagccctg ggagagcggc     1200

cctgggagag tctggagaac aggcggatgg ccccaaggcc accctccgtg gagacagctt     1260

tccagatgac ggagtgcagg acgacgatga tagactttac caagaggtcc atcgtctgag     1320

tgccacactc gggggcctcc tgcaggacca cgggtctcga ctcttacctg gagccctccc     1380

ctttgcaagg cccctcgaca tggagaggaa gaagtccgag caccctgagt cttccctgtc     1440

ttcagaagag gagactgccg gagtggagaa cgtcaagagc cagacgtatt ccaaagatct     1500

gctggggcag cagccgcatt cggagcccgg ggccgctgcg tttggggagc tccaaaacca     1560

gatgcctggg ccctcgaagg aggagcagag ccttccagcg ggtgctcagg aggccctcag     1620

cgacggcctg caattggagg tccagccttc cgaggaagag gcgcggggct acatcgtgac     1680

agacagagag gttctcggac cagcagtgac cttcaaagtg agcgccaatg tccaaaacgt     1740

gaccactgag gatgtggaga aggccacagt tgacaacaaa gacaaactgg aggaaacctc     1800

tggactgaaa attcttcaaa ccggagtcgg gtcgaaaagc aaactcaagt tcctgcctcc     1860

tcaggcggag caagaagact ccaccaagtt catcgcgctc accctggtct ccctcgcctg     1920

catcctgggc gtcctcctgg cctctggcct catctactgc ctccgccata gctctcagca     1980

caggctgaag gagaagctct cgggactagg gggcgaccca ggtgcagatg ccactgccgc     2040

ctaccaggag ctgtgccgcc agcgtatggc cacgcggcca ccagaccgac ctgagggccc     2100

gcacacgtca cgcatcagca gcgtctcatc ccagttcagc gacgggccga tccccagccc     2160

ctccgcacgc agcagcgcct catcctggtc cgaggagcct gtgcagtcca acatggacat     2220

ctccaccggc cacatgatcc tgtcctacat ggaggaccac ctgaagaaca agaaccggct     2280

ggagaaggag tgggaagcgc tgtgcgccta ccaggcggag cccaacagct cgttcgtggc     2340

ccagagggag gagaacgtgc ccaagaaccg ctccctggcc gtgctgacct atgaccactc     2400

ccgggtcctg ctgaaggcgg agaacagcca cagccactca gactacatca acgctagccc     2460

catcatggat cacgacccga ggaaccccgc gtacatcgcc acccagggac cgctgcccgc     2520

caccgtggct gacttttggc agatggtgtg ggagagcggc tgcgtggtga tcgtcatgct     2580

gacacccctc gcggagaacg gcgtccggca gtgctaccac tactggccgg atgaaggctc     2640

caatctctac cacatctatg aggtgaacct ggtctccgag cacatctggt gtgaggactt     2700

cctggtgagg agcttctatc tgaagaacct gcagaccaac gagacgcgca ccgtgacgca     2760

gttccacttc ctgagttggt atgaccgagg agtcccttcc tcctcaaggt ccctcctgga     2820

cttccgcaga aaagtaaaca agtgctacag gggccgttct tgtccaataa ttgttcattg     2880

cagtgacggt gcaggccgga gcggcaccta cgtcctgatc gacatggttc tcaacaagat     2940

ggccaaaggt gctaaagaga ttgatatcgc agcgaccctg gagcacttga gggaccagag     3000

acccggcatg gtccagacga aggagcagtt tgagttcgcg ctgacagccg tggctgagga     3060

ggtgaacgcc atcctcaagg cccttcccca gtgagcggca gcctcagggg cctcagggga     3120

gcccccaccc cacggatgtt gtcaggaatc atgatctgac tttaattgtg tgtcttctat     3180

tataactgca tagtaatagg gcccttagct ctcccgtagt cagcgcagtt tagcagttaa     3240

aagtgtattt ttgtttaatc aaacaataat aaagagagat ttgtggaaaa atccagttac     3300

gggtggaggg gaatcggttc atcaattttc acttgcttaa aaaaaatact ttttcttaaa     3360

gcacccgttc accttcttgg ttgaagttgt gttaacaatg cagtagccag cacgttcgag     3420

gcggtttcca ggaagagtgt gcttgtcatc tgccactttc gggagggtgg atccactgtg     3480

caggagtggc cggggaagct ggcagcactc agtgaggccg cccggcacac aaggcacgtt     3540

tggcatttct ctttgagaga gtttatcatt gggagaagcc gcggggacag aactgaacgt     3600

cctgcagctt cggggcaagt gagacaatca cagctcctcg ctgcgtctcc atcaacactg     3660

cgccgggtac catggacggc cccgtcagcc acacctgtca gcccaagcag agtgattcag     3720

gggctccccg ggggcagaca cctgtgcacc ccatgagtag tgcccacttg aggctggcac     3780

tcccctgacc tcacctttgc aaagttacag atgcacccca acattgagat gtgtttttaa     3840

tgttaaaata ttgatttcta cgttatgaaa acagatgccc ccgtgaatgc ttacctgtga     3900

gataaccaca accaggaaga acaaatctgg gcattgagca agctatgagg gtccccggga     3960

gcacacgaac cctgccaggc ccccgctggc tcctccaggc acgtcccgga cctgtggggc     4020

cccagagagg ggacatttcc ctcctgggag agaaggagat cagggcaact cggagagggc     4080

tgcgagcatt tccctcccgg gagaggagat cagggcgacc tgcacgcact gcgtagagcc     4140

tggaagggaa gtgagaaacc agccgaccgg ccctgcccct cttcccggga tcacttaatg     4200

aaccacgtgt tttgacatca tgtaaaccta agcacgtaga gatgattcgg atttgacaaa     4260

ataacatttg agtatccgat tcgccatcac cccctacccc agaaatagga caattcactt     4320

cattgaccaa gatgatcaca tggaaggcgg cacagaggca gctgtgtggg ctgcagattt     4380

cctgtgtggg gttcagcgta gaaaacgcac ctccatcccg cccttcccac agcattcctc     4440

catcttagat agatggtact ctccaaaggc cctaccagag ggaacacggc ctactgagcg     4500

gacagaatga tgccaaaata ttgcttatgt ctctacatgg tattgtaatg aatatctgct     4560

ttaatatagc tatcatttct tttccaaaat tacttctctc tatctggaat ttaattaatc     4620

gaaatgaatt tatctgaata taggaagcat atgcctactt gtaatttcta actccttatg     4680

tttgaagaga aacctccggt gtgagatata caaatatatt taattgtgtc atattaaact     4740

tctgatttca cattcaaaaa aaaaaaaaaa aa                                   4772


<210>  925
<211>  3617
<212>  DNA
<213>  homo sapiens

<400>  925
aagtttccaa gtggtcaact tgaccgatgc tttggcaatt gaaaaagggc agaaaggcgc       60

gggctagtgg gtggatgggg acaaagatct aagtcacctt cttccagcgt gtgagcctgg      120

gaggagggtg ggggtcctga ggagcaagag gtacgaggaa ggaaaaggag agggcttctg      180

ggttagtttc cacctcctgc tttccaactc acggcgcttt ccttccggaa aggacgctgg      240

attcagggcg cgccagtacg cgcagtagcg gcccgcgagt cggcaggtgg gtagccccgg      300

cgcgggagga aggggaagtt accttcccct cggaagaggg cgctggctcc cccatcctgc      360

ctttataata aggccaccgg aggagaggaa gcagccagct gccgtctgcg ctttgcaaag      420

catgcagtta ggggagcagc tcttggtgag ctcagtgaac ctgcctggcg cgcacttcta      480

cccgctggag agtgcgcgag gcggcagcgg cgggagcgct ggccacctcc ccagcgcggc      540

cccctctcct cagaagttgg acttagacaa agcgtccaag aagttttccg gcagtctctc      600

ctgcgaggcg gtgagcgggg agcccgcagc cgccagcgca ggggcccccg cggccatgct      660

tagtgacacc gacgccgggg acgcatttgc cagcgctgcg gcagtggcca agccggggcc      720

cccggacggc cgcaagggct ccccctgcgg ggaggaggag ctgccctccg ccgctgcagc      780

cgccgccgcc gccgccgccg cggctgcggc cactgcgcgc tactccatgg acagcctgag      840

ctccgagcgg tactacctcc agtcccccgg tcctcagggg tcggagctgg ctgcgccctg      900

ctcactcttc ccgtaccagg cggcggctgg ggcgccccac ggacctgtgt acccggctcc      960

taacggggcg cgctacccct acggctccat gctgcccccc ggcggcttcc ccgcggctgt     1020

gtgcccaccc gggagggcgc agttcggccc aggagccggt gcgggcagtg gcgcgggcgg     1080

tagcagcggc gggggcggcg gcccgggcac ctatcagtac agccaggggg ctccgctcta     1140

cgggccgtac cctggagccg cagcggcggg atcttgcgga ggactggggg gcctgggggt     1200

tccaggttct ggcttccgtg cccacgtcta cctgtgcaac cggcctctgt ggctcaaatt     1260

ccaccgccac caaactgaga tgatcattac gaaacagggc aggcgcatgt ttcctttctt     1320

gagcttcaac ataaacggac tcaatcccac tgcccactac aatgtgttcg tagaggtggt     1380

gctggcggac cccaaccact ggcgcttcca ggggggcaaa tgggtgacct gtggcaaagc     1440

cgacaataac atgcagggca acaaaatgta tgttcaccca gagtctccta atactggttc     1500

ccactggatg agacaggaga tttcattcgg gaaattaaaa ctcaccaata acaaaggcgc     1560

aaataacaac aacacccaga tgatagtctt acaatcctta cacaaatacc aaccccgact     1620

gcatattgtt gaagttacag aggatggcgt ggaggacttg aatgagccct caaagaccca     1680

gacttttacc ttctcagaaa cgcaattcat tgcagtgact gcctaccaaa acaccgatat     1740

tactcaacta aagattgatc ataacccctt tgcaaaaggc ttcagagaca actatgattc     1800

atcccatcag attgtccctg gaggtcggta cggcgttcaa tccttcttcc cggagccctt     1860

tgtcaacact ttacctcaag cccgctatta taatggcgag agaaccgtgc cacagaccaa     1920

cggcctcctt tcaccccaac agagcgaaga ggtggccaac cctccccagc ggtggcttgt     1980

cacgcctgtc cagcaacctg ggaccaacaa actagacatc agttcctatg aatctgaata     2040

tacttctagc acattgctcc catatggcat taaatccttg ccccttcaga catcccatgc     2100

cctggggtat tacccagacc caacctttcc tgcaatggca gggtggggag gtcgaggttc     2160

ttaccagagg aagatggcag ctggactacc atggacctcc agaacaagcc ccactgtgtt     2220

ctctgaagat cagctctcca aggagaaagt gaaagaggaa attggctctt cttggataga     2280

gacaccccct tccatcaaat ctctagattc caatgattca ggagtataca ccagtgcttg     2340

taagcgaagg cggctgtctc ctagcaactc cagtaatgaa aattcaccct ccataaagtg     2400

tgaggacatt aatgctgaag agtatagtaa agacacctca aaaggcatgg gagggtatta     2460

tgctttttac acaactccct aaagagttat tttaacctca aaaattagct aactttttgc     2520

agatggactt ggtggtgttt tttgttgtct tctttgccta ggttgccaaa aagatgtttg     2580

ccttccacct tgatgcatcc tgttttgtgc aattctctaa aagaaggtgc caaagctttt     2640

tgattgctgc aggtaactga aacaaaccta gcatttttaa aaaataagat taatggaaga     2700

ctttaaggta ttttaaaatt cgaagggtat ccaaggttct gtatttattt attggggaga     2760

cactaaccct tcaaagaagc aggctgtgaa cattgggtgc ccagtgctat cagatgagtt     2820

aaaacctttg attctcattt ctatttgtaa attcttaagc aaatagaagc cgagtgttaa     2880

ggtgttttgc ttctgaaaga gggctgtgcc ttccgtttca gaaggagaca ttttgctgtt     2940

acattctgcc aggggcaaaa gatactaggc ccaggagtca agaaaagctt ttgtgaaagt     3000

gatagtttca cctgactttg attccttaac ccccggcttt tggaacaagc catgtttgcc     3060

ctagtccagg attgcctcac ttgagacttg ctaggcctct gctgtgtgct ggggtggcca     3120

gtgggactca ggagagagca agctaaggag tcaccaaaaa aaaaaaaaaa aaaaagggag     3180

aatttaaaag tgtacagttg tgtgtttaga tacactatag aataatgtgg tatatattgt     3240

acaaatagtc tacataggtg tctgggataa tgtaaaactg gtgctttggc tttgtaaaga     3300

atttgcaaat cacttaacag ctgcaggggc aaggggagag tttcatcatc cccatgatat     3360

ttgggaatat tctgtttact tcttagatag ttaagaatgt attcagctac tatgtactaa     3420

cttgaaccgt gtttaaggaa aactcctatt tcatcctctt cttgcgccat cccctctccc     3480

taacttggta atgtgaagaa actaaaacct gataccacag ctcctatagg cattttagag     3540

atcttggatt tttatgtaca gtcttagtca tttttaataa atgtggttca gtaagggaac     3600

ggaaaaaaaa aaaaaaa                                                    3617


<210>  926
<211>  4611
<212>  DNA
<213>  homo sapiens

<400>  926
ccccgtctgc gtccgcgttc gcggctcccg tttgcatcat ctccagccgg cggctgctcc       60

agggaggctg ggcgcgatcc tctccgcccg cggctccaac ccgcactctg cgcctctcct      120

cgcctttctc gcacctgctc ctgcgccagg cccggagacc cccggggcgg cttcccagaa      180

cctgcggagc acaactggcc gaccgaccca ttcattggga accccgtctt ttgccagagc      240

ccacgtcccc tgccacctct agctcggagc ggcgtgtagc gccatggaga agagcaacga      300

gaccaacggc taccttgaca gcgctcaggc ggggcctgcg gccgggcccg gagctccggg      360

gaccgcggcg ggacgcgcac ggcgttgcgc gggcttcctg cggcgccaag cgctggtgct      420

gctcaccgtg tccggggtgc tggcgggcgc gggcctgggc gcggcgttgc gcgggctcag      480

cctgagccgc acgcaggtca cctacctggc cttccccggc gagatgctgc tccgcatgct      540

gcgcatgatc atcctgccgc tggtggtctg cagcctggtg tcgggcgccg cctcgctcga      600

tgccagctgc ctcgggcgtc tgggcggcat cgctgtcgcc tactttggcc tcaccacact      660

gagtgcctcg gcgctcgccg tggccttggc gttcatcatc aagccaggat ccggtgcgca      720

gacccttcag tccagcgacc tggggctgga ggactcgggg cctcctcctg tccccaaaga      780

gacggtggac tctttcctcg acctggccag aaacctgttt ccctccaatc ttgtggttgc      840

agctttccgt acgtatgcaa ccgattataa agtcgtgacc cagaacagca gctctggaaa      900

tgtaacccat gaaaagatcc ccataggcac tgagatagaa gggatgaaca ttttaggatt      960

ggtcctgttt gctctggtgt taggagtggc cttaaagaaa ctaggctccg aaggagaaga     1020

cctcatccgt ttcttcaatt ccctcaacga ggcgacgatg gtgctggtgt cctggattat     1080

gtggtacgta cctgtgggca tcatgttcct tgttggaagc aagatcgtgg aaatgaaaga     1140

catcatcgtg ctggtgacca gcctggggaa atacatcttc gcatctatat tgggccatgt     1200

tattcatgga ggaattgttc tgccacttat ttattttgtt ttcacacgaa aaaacccatt     1260

cagattcctc ctgggcctcc tcgccccatt tgcgacagca tttgctacct gctccagctc     1320

agcgaccctt ccctctatga tgaagtgcat tgaagagaac aatggtgtgg acaagaggat     1380

cagcaggttt attctcccca tcggggccac cgtgaacatg gacggagcag ccatcttcca     1440

gtgtgtggcc gcggtgttca ttgcgcaact caacaacgta gagctcaacg caggacagat     1500

tttcaccatt ctagtgactg ccacagcgtc cagtgttgga gcagcaggcg tgccagctgg     1560

aggggtcctc accattgcca ttatcctgga ggccattggg ctgcctactc atgacctgcc     1620

tctgatcctg gctgtggact ggattgtgga ccggaccacc acggtggtga atgtggaagg     1680

ggatgccctg ggtgcaggca ttctccacca cctgaatcag aaggcaacaa agaaaggcga     1740

gcaggaactt gctgaggtga aagtggaagc catccccaac tgcaagtctg aggaggagac     1800

atcgcccctg gtgacacacc agaaccccgc tggccccgtg gccagtgccc cagaactgga     1860

atccaaggag tcggttctgt gatggggctg ggctttgggc ttgcctgcca gcagtgatgt     1920

cccaccctgt tcacccagcc gccagtcatg gacacagggc actgcccttg ccaactttta     1980

ccctcccaag caatgctttg gcccagtcgc tggcctgagg cttacctctc ggcactggca     2040

ttgggctccc cagccggaac tggttaccaa ggacaaggac actctgacat tcggcttgat     2100

ccatgtccag gtgcaactgt gtgtacacca gggatctgtt tggaaacaac cccttgagct     2160

gccaggctca agaaatcatg gactcacagg gtcctgtgtg gttacatctt ggaaaaaatg     2220

cagatgtatt tcactctccc cggtcagctc tgcatcaggt gttttctgag caaaccaagg     2280

gggtttatag tcatctgtcg cattgcctcg agttgcagta attgaaaaaa tgctcaaatt     2340

cttagccatg gctggccttt gctgagctgg gactcaggtg tttaaagagt ttgtgctata     2400

gctaggtgtg gatagcttct gatccctggg ttctgggaga ctgcaggtgc cgcacattgt     2460

caagttagaa atactccagg tgggtgttag cactgtggtg gtctctggtc cacagcctta     2520

ggtaaacaac ttagattctg aggtcaaaga aaaaaggaga gggaatgcag ccttgtgggg     2580

gagaagcggg gcagagggtt ctctaatcta atcaggacag gacaggtttc acatacaatt     2640

gtcccagttc gcatcccagc cctggggcac ttttctgctt ccttccagag gcctgggcct     2700

ctgataacac tttggctttt tctccattca cgctgatttg gcaaaaggcc agagatgggc     2760

ctccttccct ggggaggtgt gatgtagtta tcacattcag gacccttgtt gatttatcat     2820

ctattatttg aattcaactg gacactctgt aaaatgctgc actgcagcaa aaacaaaacc     2880

accaccaccc cagagaaaac catgtactaa ttggagtggg gtacccccat tcacaggttc     2940

ccaggtcccc tggctttggc tgatttcaaa atatagagcc ctttcttgcc agtacatcca     3000

agtttaaaat tatcagcgaa atggtccatg tttttccaat tacctgctga cacggttcta     3060

agctaagtga aggggaagat ctgagagcgt gctgtttgtg gctgttgatg catattcgtg     3120

atgtaacagg tcctggggcc tcactttacc ccatttgtaa aatggggcta atgtcacctg     3180

cctcttacct acctcagagg gatttggtga agcaaactgt taatcttcga aaacgaccat     3240

ttcacttctt ggatatcaag tgctaaccca gtatgttctt cttttttatg taagggacag     3300

ctttctccac agagtccttt ctgctggtga ggacagcatt tctgagcagg gctttgttct     3360

ctatgtgcat taggactttt atcatgccct tgttctgtgt gtagttactt gacagcatca     3420

aatgccgcct cttcctaatg tccttcaagt tttcatgaac tagcaacccc accttccacc     3480

atggttctgg gcgcctgatt ttgctgtgac tcccagaccc agccactgtt tctgccaccc     3540

tgtaacaggc cattaaagct ccccagtgtt cagcctcctt cactcccttg ttttccctgt     3600

tgctatgtgt cacctgggcc ctacagacag gggcacacgc ttatggatgt gtgtaccatt     3660

gagatgagaa tgggtagatg gaacggagac catcaagcca cacccccttc ttaaaactgg     3720

ggacatgagc ctgagcagaa agggtgaaga agagccatgg gacacagagt tgacccagcc     3780

agggggaaag cccagctctc tttaaaccag ctaagccatt ccagtctcct gtgaagccaa     3840

aagggaccag gaaccgtgca aaggaaactg gaaacttttc cccgctgggt agagcatgtt     3900

gctgatactc ttctgttttc aagggaaaca atcacattgt ttgattccaa atggtaaatg     3960

aacactcact attcttcagg cttcagtaaa tctttttttc ttccttcata tatatataca     4020

caacacacac acacatatgt atatctatac acacatgtgt gttgtgtata tgcatgtgtg     4080

tgtgtgcgtg tgtgtatagt tttagctcca agccaagcaa gtttgtgttt ggatagaggg     4140

gaacttaact attaactaca agttgtatgt ctgtggtatc ttgattttcc catttctaaa     4200

gatgaatttc acaaagccat aaagcgtgaa attagagctg gacttaagac tcattggccg     4260

accatcctgt gtcctggcct ggccctgcag taagaagcgt gtctgggtct ggagaagggt     4320

gcttccgaga gtgtgcaggt ggcccttccc cttggaggcg agaagagaga atgtgctgtc     4380

tatcttcctg gttttcagtc cacagagtcg gtagaccagg ggttacgtga ctggggaaaa     4440

tctcacatct ccttgtctga aaacatttcc cctgctgttc tctttctaac atgttgtggt     4500

aaatctgttc agatactgct catctgactg ttttgtacat gtgacaattg ccttaaaacc     4560

tagcacagtc ctcagaaatg aataccgtgt ttccactgga aaaaaaaaaa a              4611


<210>  927
<211>  2257
<212>  DNA
<213>  homo sapiens

<400>  927
ttggctgtca gtcggatccg agaacgacga ttggctttcc ttgaccgtcc ctcaagcgcc       60

tctccggaga tggtctgagg tgggagaaga gctgaagaga cctggagccg acagacgggt      120

gaaggccatg ccgcctcctg ggaaagttcc ccgaaaggag aatctgtggc tacagtgtga      180

gtgggggtcc tgctcctttg tgtgctcaac catggaaaag ttctttgagc atgtcactca      240

gcacctgcag cagcacctgc atggctctgg ggaggaggag gaagaggaag aggaggatga      300

cccacttgag gaagaattct cctgcttgtg gcaggaatgt ggcttttgtt ctctggacag      360

ttctgctgac ctcatccgcc atgtctactt ccactgctac cacaccaagc tgaaacagtg      420

ggggctgcag gccttgcaaa gccaggctga ccttggcccc tgcatcctgg acttccagag      480

ccggaacgtc atccctgata tccctgacca cttcctgtgt ctgtgggagc actgtgagaa      540

ttccttcgac aatcctgagt ggttttatcg gcatgtggaa gcacacagtc tgtgctgtga      600

atacgaagca gtcggcaagg acaacccggt ggtgctgtgt ggctggaaag gctgtacctg      660

caccttcaag gaccgcagta aacttcgaga gcacctccgc agccataccc aggagaaagt      720

ggtagcctgc cccacctgtg ggggcatgtt tgccaacaat accaagttct tagatcacat      780

ccgtcgccag acctcattgg atcagcagca cttccagtgt tctcactgtt ccaagagatt      840

tgccacagag cggctattgc gggaccacat gcgcaaccat gtgaatcact ataagtgccc      900

tctgtgtgac atgacctgcc cgctgccttc ctccctccgc aaccacatgc gctttcgtca      960

cagtgaggac cggcccttta aatgtgactg ttgtgactac agctgcaaga atcttattga     1020

cctccagaag cacctggata cccacagcga ggagccagcc tacaggtgtg attttgagaa     1080

ctgcaccttc agtgcccgat ccctctgctc tatcaagtcc cattaccgca aagtacatga     1140

aggagactct gagccaaggt acaaatgtca tgtgtgtgac aaatgcttca cacggggcaa     1200

caacctcacc gtgcaccttc gcaagaagca ccagttcaag tggccctcag ggcatccccg     1260

ttttcggtac aaggaacatg aagatggcta tatgcggctg cagctggttc gctacgagag     1320

tgtagagctg acacagcaac tgctgcggca accacaagag ggatcgggcc tgggaacgtc     1380

gctgaacgag agcagcctgc agggcattat tctagaaaca gtgccagggg agccaggacg     1440

taaggaagag gaagaggagg gcaagggtag cgaagggaca gccctctcag cctctcagga     1500

caaccccagt tctgtcatcc acgtggtgaa tcagaccaat gcccaaggcc agcaagagat     1560

tgtctactat gtgctgtctg aagccccagg ggagcctccc ccagcccctg agccaccttc     1620

agggggcatc atggaaaagc ttcaaggaat agctgaggag ccagagatcc agatggtttg     1680

aaggccgcag agccagacca tttcttcccc aggtcctgaa gtttgagcca ggcaagtggc     1740

agtgccccta gtgggcagcc gttgccaatg gatgccttta ggagtggtgc cgagagcagt     1800

gtggtccact ctggcctggg tttgcatcat tctgcagact ctaaagactt cccttttctg     1860

ccagactaca ttttgtgggg agcctgagga ctctggattc tttgagggga tcctggatgt     1920

gtgtgttctt gttaaagagg ctgttatcag gcttaaccat aaccctcaag atctgcttga     1980

cagtgattaa atccttagct cacatccatt cccatctttc gggctcctta ggcccaagga     2040

tggcatgtga ctggtccctg caagggtcct ttctttgtca ccagccaagg cattgataac     2100

caagtagcca ttttcctctt aaggtttcct ctacaacccc aaggactttc atgattatcc     2160

tcagggacag gattggaggc attgagcgtg tttattaaca aattgttttt ggtaataaaa     2220

taaatgcttg gactcttaaa aaaaaaaaaa aaaaaaa                              2257


<210>  928
<211>  1906
<212>  DNA
<213>  homo sapiens

<400>  928
agtgacgccc ccgaacccag ctgcagaagc tgccgccacc tccaatgcac aaggtgtctc       60

atctgaaaag aaacctgagc cccagggagg cggcgcggag cgaccctggc agagctggcg      120

caaacagggc gagaggtcgc tgggcagcgt tcgaggacca gagggagctc ggccacagaa      180

gaccccagtg atctgatccc gggatcccgg ctccaagctc tcctcgcatt ttacagattt      240

cacccccgcg actatctccc caaaacggag cctttatatc aagagaaggt gcgggagctg      300

gggcaaccag gactttctcg ggcacccaag atgcgctcca ttaggaagag gtggacgatc      360

tgcacaataa gtctgctcct gatcttttat aagacaaaag aaatagcaag aactgaggag      420

caccaggaga cgcaactcat cggagatggt gaattgtctt tgagtcggtc acttgtcaat      480

agctctgata aaatcattcg aaaggctggc tcttcaatct tccagcacaa tgtagaaggt      540

tggaaaatca attcctcttt ggtcctagag ataaggaaga acatacttcg tttcttagat      600

gcagaacgag atgtgtcagt ggtcaagagc agttttaagc ctggtgatgt catacactat      660

gtgcttgaca ggcgccggac actaaacatt tctcatgatc tacatagcct cctacctgaa      720

gtttcaccaa tgaagaatcg caggtttaag acctgtgcag ttgttggaaa ttctggcatt      780

ctgttagaca gtgaatgtgg aaaggagatt gacagtcaca attttgtaat aaggtgagct      840

ttcttctgct ttttgagatt gtaagttttt caaagatatt ttacttgggg gtggaaaact      900

gttagaaaat tttaaagtat tactaaaacc tcaaacaaat atttgtctat gatatccttt      960

tctgtgcaac atttaaatta catttaccct ggaatagaat attataatta ttgcgtagtt     1020

gaaagaaaaa gtgatcctgt catagcaaca agattcacac agcttttttt ggtgaggtga     1080

ggggggaggc aaatggcaat tttattaaat ttaatattcc acacaaactt ttttcttagt     1140

atctcttctt catactcatt agttttgtgt gattttattt gttgtataaa gattatgaat     1200

attactatgg aatgatgtaa tagatttatg ttaatgttac tttttattaa taattatcta     1260

ggagatagta agaacatagt ttagcaagtt tatatttgat atcctgagcc atatttcttt     1320

aatttctctt tatatgtggt atttgtgtat gttagtatat ttgaatttta tgttttttta     1380

acataattaa gcgtgcatgt ttgtttttca ttaacggtta aaagatattt gatgaattgt     1440

gtgtttgatt aacctattaa ctgaaaaaaa ctcaacagta gaaatggaat tataatcaca     1500

tcataaatat aagcagtttt taatgatcaa tttttatatc tgtacagttt ttttggattg     1560

ttttagttcc ttagaaaaat tagctaaatg acagaaacat ggatattgaa atatgaaata     1620

gtacaatata aagatagata gaaaagtatg ctgagttgac atgttgaaaa acacagtctc     1680

ttgaagatat actggaatac attatttttg aatattttga atattttttg aatattttta     1740

aataaagtct taaaagcata aataggtaac tacttttaaa aaaaaagtca tgagaaatca     1800

cactcaagca ttatcaagtg aagaaaattc ataatagcaa ataaaactgc aaacatttta     1860

ccttaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                    1906


<210>  929
<211>  2000
<212>  DNA
<213>  homo sapiens

<400>  929
agtcgctgag ccctggcgcc tccttaaagc cgcagctccg ccccgaccgc cccgcccgcc       60

agtccgtcct cagaccctcc caaccgccgg gtccccgccg cctcggcgga gtgttgtaga      120

gcctcgagcc tgcgaggagc gcgccgcccg ccagctccct gcgtcccgtc ccgcgtcccc      180

gcgttcccgc gtcctgcgat ccgccgccat ggccagtgag gagctggcgt gcaagctgga      240

gcgccggctg cggcgcgagg aggccgagga gagtggcccc cagctggctc ccctcggcgc      300

cccagccccg gagcccaagc ccgagcccga gcctcccgcc cgtgcgccca cggccagcgc      360

cgacgcggag ctgagcgccc agctgagccg gcggctggac atcaacgagg gcgctgcgcg      420

gccccggcgc tgcagggtct tcaaccccta cacggagttc ccggagttca gccgccgcct      480

catcaaggac ctggagagca tgttcaaact gtatgacgct gggcgggatg gcttcatcga      540

cctgatggag ctgaagctga tgatggagaa gctgggggcc ccccagaccc acctgggcct      600

gaagagcatg atcaaggagg tggatgagga cttcgatggc aagctcagct tccgggagtt      660

cctgctcatt ttccacaagg ccgcggcagg ggagctgcag gaggacagtg ggctgatggc      720

gctggcaaag ctttctgaga tcgatgtggc cctggagggt gtcaaaggtg ccaagaactt      780

ctttgaagcc aaggtccaag ccttgtcatc ggccagtaag tttgaagcag agttgaaagc      840

tgagcaagat gagcggaagc gggaggagga ggagaggcgg ctccgccagg cagccttcca      900

gaaactcaag gccaacttca atacatagtc ctgctgacct tgccctctgc ccacagctgt      960

gcctcacaga tgccccgaga agagatgact aggcatcttc atcactgctg tcggtcccct     1020

ccctgagcca gcatctccat ccaccacccc gtgccagctc ccgtgccagc cttcattcct     1080

cccagtgtcc aagcccctcc aggagggtcc tggggtgggc cagatgcctg cccacctctg     1140

tctcctgcct ctgctcctct gcccttctta tagccagaac ttgtatcttc tcagcaacct     1200

tcactttgtc cttgtccctt taccattccc catcaaagag tagtctgcta tatcaatttg     1260

tgtagatatg tctgtctttt tgggtcctca gagaaaatgc ccattttctc ggagaattct     1320

ctgcactcct ctctgcttca cattcaactt ccctgttctc atctttggta ggattctgcc     1380

agttgctttt gcatcttctg ttcctgggta atggtgggtc ttaatggagg ctgggtggac     1440

cactgcccgt ccactcttca acaggaggaa cagcatgcca ccatagtaac acacattaga     1500

gaaaggacag aggtctgctc cttcctgcca cctttctcct ggccccttag cattccccca     1560

gtccctccct cttcaccttg ctccgtctat gtcttcccag ctcagccttt tccccactct     1620

taaatactgt actacttcac tgtaagaacg aaagaatagt taggatacca atgagtaaaa     1680

gggttcctgt tcactctgac tctgtgcaaa ttgtattaca gtagaccgct gacgttccca     1740

agtgacagat ccagggcctt tcaaacatcc ccaaagtcat ggccatactc accattagcc     1800

agtttctaac atctgtttca gggtatccag ctgtagatgt tcttatcccc catacttgtg     1860

agttcttggg gttgctcaca aatactaggg gtttttgttg tatttttaac aaatatatcc     1920

taatgtcata tttattctct tttgtaactg ctgtctttac aataaagaaa tcatctgcct     1980

ttctatctta aaaaaaaaaa                                                 2000


<210>  930
<211>  5149
<212>  DNA
<213>  homo sapiens

<400>  930
gggggcgggg cggggcgcag ctccgacttc ggacatggcg cacgctggcg gtggcagcgg       60

tggcagcggt gccggcggcc ccgcgggccg ggggctgagc ggcgcccgct ggggtcgctc      120

gggctccgca ggccacgaga agctgccggt gcacgtagaa gacgccctca cctatctgga      180

ccaggtgaag atccgctttg gcagcgaccc tgccacctac aacggcttcc tggagatcat      240

gaaggagttc aaaagccaga gcatcgatac tcctggagtc atcagacgtg tctcgcagct      300

cttccacgag caccctgacc tcattgttgg attcaacgct tttcttcccc tcggatatag      360

aatagacatt cccaagaatg gcaagttaaa catacagtcg cctctgacaa gccaggagaa      420

ttcgcacaac cacggggacg gtgcagagga cttcaagcag caggtgccgt ataaagagga      480

caaaccccag gtgcccctgg agtccgattc cgtggaattc aacaacgcca tcagctatgt      540

gaataagatt aaaacccgct tcctagacca cccagaaatc tacaggtcat tcctggagat      600

cctgcacacg taccagaagg agcagctgaa cacgaggggc cggccattcc gaggcatgtc      660

tgaagaggag gtgttcaccg aggtggccaa cctcttccgg ggccaggagg acctgctctc      720

agagtttgga cagttcctgc ccgaagccaa gcggtctctg ttcacaggaa acgggccgtg      780

cgagatgcac agcgtgcaga agaacgagca cgacaagacc ccggagcaca gcaggaagcg      840

ctcccggccc tcgctcctcc gccccgtgtc tgcacccgcc aagaaaaaaa tgaaacttcg      900

tggtaccaaa gacctgtcca tcgctgcagt ggggaagtac gggactctgc aggaattttc      960

tttctttgac aaggtccgcc gggtgctgaa gagccaggag gtgtatgaaa acttcctccg     1020

ctgcatcgca ctcttcaacc aggagctggt gtctggctct gagctcctgc agctcgtcag     1080

cccatttctg gggaaatttc cagaactctt tgcacagttc aagtccttcc tgggggtaaa     1140

agagctgtcc ttcgcgccac ccatgagcga cagatccggg gacgggataa gccgggaaat     1200

tgattatgca tcctgcaagc gcataggatc cagctaccgg gcactcccca aaacctacca     1260

gcagcccaag tgcagtggga ggacagccat ctgcaaggag cttgaccatt ggacacttct     1320

ccagggttcg tggacagacg attactgcat gtccaagttc aagaatacct gctggattcc     1380

aggatatagt gcaggggtac tgaacgacac ctgggtctcc ttcccttcct ggtctgagga     1440

ctccacgttc gtcagctcca agaagacacc gtacgaggag cagcttcacc gctgtgagga     1500

cgagcgcttc gagttagacg ttgtcctgga gacgaacctg gccacaatcc gtgtgttgga     1560

aagtgtgcag aagaagctgt ctcggatggc gccggaagac caggagaagt tccggctgga     1620

cgactccctg ggaggcacgt cggaggtgat ccagcgccgt gccatttatc gcatctatgg     1680

cgacaaggcc ccggagatca tcgagagcct caagaagaac cctgtcaccg ctgtccccgt     1740

tgtcctgaaa agactgaagg ccaaggaaga ggagtggcgg gaggcccagc agggcttcaa     1800

caagatctgg cgggagcagt atgagaaggc gtacctcaag tcccttgacc accaggctgt     1860

gaacttcaag cagaacgaca ccaaggccct gcgctccaag agcttgctca acgagatcga     1920

gagcgtctac gacgagcacc aggagcagca ctcggagggc cgcagtgccc cctctagcga     1980

gccgcacctc atctttgtgt acgaggaccg gcagatcctg gaggacgcag cagcgctcat     2040

cagctactac gtgaagcggc agccggccat ccagaaggag gaccagggca ccatccacca     2100

gctgctgcac cagttcgtgc ccagcctctt cttctctcag cagctggacc tgggcgcctc     2160

cgaggagtca gctgatgagg accgggacag cccccagggg cagaccacag accccagtga     2220

gcggaagaag ccggcgccag gaccccacag tagcccccca gaggagaagg gggccttcgg     2280

ggatgccccg gccactgagc agccacccct gccgccccca gccccgcaca agcccctgga     2340

cgatgtctac agcctatttt ttgccaacaa caactggtac ttcttcctgc gcctgcacca     2400

gaccctgtgc tccaggctgc tgaagatcta ccgccaggcg cagaagcagc ttctggagta     2460

tcggaccgag aaggagcggg agaagctgct gtgtgagggc cgcagggaga agggcagcga     2520

ccccgccatg gagctgcggc tgaagcagcc cagtgaagtg gagctggagg agtactaccc     2580

ggccttcctg gacatggtgc ggagcctgct ggagggcagc atcgacccca cgcagtacga     2640

ggacacccta cgcgagatgt tcaccatcca tgcctacgtg ggcttcacca tggacaagct     2700

ggtgcagaac attgcgcggc agctgcacca cctcgtgagc gatgacgtct gcctgaaggt     2760

ggtggagctc tacctgaacg agaagaagcg gggtgccgct ggtgggaacc tgtcctcccg     2820

ctgcgtccgc gctgctaggg agaccagcta ccagtggaag gctgagcgct gcatggccga     2880

cgagaactgc ttcaaggtga tgttcctgca gcgcaaaggg caggtgatca tgaccatcga     2940

gctcctggac accgaggagg cccagacgga ggaccctgtg gaggtccagc acctggctcg     3000

gtacgtggag cagtatgtgg ggaccgaggg cgcgtccagc tcgcccactg agggcttcct     3060

cctgaaacct gtgttcctgc agaggaacct caagaagttc cgccgccggt ggcagagcga     3120

gcaggcgcgg gccctgcgcg gtgaggccag gagctcctgg aagcggctgg tgggcgtgga     3180

gagcgcctgc gacgtggact gccgcttcaa gctcagcact cacaagatgg tgttcatcgt     3240

gaactccgag gactacatgt accgtcgcgg gaccctctgc cgggccaagc aggtgcagcc     3300

cctggtcctg ctccgccacc accagcactt tgaggagtgg cacagccgct ggctggagga     3360

caatgtgacg gtggaggcgg ctagcctggt gcaggactgg ctgatgggtg aggaggacga     3420

ggacatggta ccctgcaaga cgctgtgtga gacagtgcac gtgcacggcc tgcccgtgac     3480

ccgctaccgc gtgcagtaca gccgccgccc ggcctcgccc tgacccgccc tcatgggcac     3540

cgggcaggcg cctcacagag cacagacgtg ccctcggcct tggtcgtgtc ggggccgttt     3600

tcttgaacga cgtgagaggc atctcccagc ccctctgctg ccggacagcg cactccaggg     3660

caggacgccg cccccgtggc tcccggtctc ctgtgggcct gctgtgtgcc aaacctgagc     3720

tacctgcacc cgagccctgg ggctcagccc caccacaggg gcgggtggac gtgctggccg     3780

aggaacaagc aatcatgttt gcgtccccgt ccgtcacatg tgccaaatcc ctggcaggca     3840

gatggctcct gccccatatt cttgccgtgt cttggaaaag tcacaggtga cagccctcct     3900

gaggcccaca ctttggaggg ggtccatgtc caagagaccc tgacaaggaa ggagttgagc     3960

cctgggtagg cttgcttgaa aagtgagtcc ttccagaata ttctcagagc tgccagaaac     4020

atcatctgag ggtttgggca tcagctctgc ctggctggtg ttcaggccct cagtcacttt     4080

ggaagtgaga agaacccttc agccaaacct ttgggatccc attttgaagt ccagagctgg     4140

agcaggcggg cagtgccctg ggagaccccg ctctggataa gacacccaac cccaactcca     4200

gcagctggac tctgggccca caaggggagg gaccccagcc agtattccct cagagccggc     4260

acgaccctgc tgtggggcgg cgggcccagt cgtgttcctg cagtgggcac cctaggcgta     4320

tgtgtataca cgcacagata tttattcctt tcgcttttag tggttgttat ttctgtagca     4380

gccaagtcct gcggctccct ggggctgaga tctccctttg tggaactccg agagccgccc     4440

tgacagtccc agccgccacc caaggagccc catccgccca cccaccctgg gacccacgcg     4500

gccactccag ggatcattgt tgtccttttg tgaggggctg aggcgactgt cccatggagg     4560

catccaaggc tttctgtgcc aagaatccca agtgactggg gctggggacc acttctccag     4620

gcctctctcc ccgaccatga gagcccctgg ccctggcccc tgcacaccag taggcccaga     4680

ataaccgcca cccttgccat cctgcaacag ctggactcaa gtttccagga agtggagatg     4740

tgtttctaga agtttcctgt ggaacctgga ggctcctgat gcctttgact ccaggctggg     4800

cgattccgat gctgacccgt cctcctgggc tccccacccc cgctccccaa gtgtcacaca     4860

ggcactttgt acacatcctg gttttctaag aagggaactt gccatcaaga ttcctgtacc     4920

aggcccacgg ccgtctcggg cagagccacc tgggccccgg gtgcagccgg agaccccgcc     4980

gagcccctcc tcccagtatt cccatccccg catgcttcta gggagcgcct cttttccgtt     5040

cttgaggaat ttctgttctg gggcttgtcc ttcctttgca gctgttttga atgtagtttt     5100

ccttttctat ttatttgcac attaaagtta ataattgaat attgacatc                 5149


<210>  931
<211>  1994
<212>  DNA
<213>  homo sapiens

<400>  931
catattcagc agggttagct tgtcctcccc tccctcttca gcttcccaga cactgagtct       60

ggaatgaaaa ttcacctgcc tctgagttgg ctcctaatgg gggtgggagt gttacttcgg      120

ttcccaggtt ggaagattat ctcacccggc cccagctata taagctgacc ggtgtggagg      180

ggcccagcag ggccaactcc agggattcct tccacgacag aaaaacatac aagactcctt      240

cagccaacat gatggtactg aaagtagagg aactggtcac tggaaagaag aatggcaatg      300

gggaggcagg ggaattcctt cctgaggatt tcagagatgg agagtatgaa gctgctgtta      360

ctttagagaa gcaggaggat ctgaagacac ttctagccca ccctgtgacc ctgggggagc      420

aacagtggaa aagcgagaaa caacgagagg cagagctcaa aaagaaaaaa ctagaacaaa      480

gatcaaagct tgaaaattta gaagaccttg aaataatcat tcaactgaag aaaaggaaaa      540

aatacaggaa aactaaagtt ccagttgtaa aggaaccaga acctgaaatc attacggaac      600

ctgtggatgt gcctacgttt ctgaaggctg ctctggagaa taaactgcca gtagtagaaa      660

aattcttgtc agacaagaac aatccagatg tttgtgatga gtataaacgg acagctcttc      720

atagagcatg cttggaagga catttggcaa ttgtggagaa gttaatggaa gctggagccc      780

agatcgaatt ccgtgatatg cttgaatcca cagccatcca ctgggcaagc cgtggaggaa      840

acctggatgt tttaaaattg ttgctgaata aaggagcaaa aattagcgcc cgagataagt      900

tgctcagcac agcgctgcat gtggcggtga ggactggcca ctatgagtgc gcggagcatc      960

ttatcgcctg tgaggcagac ctcaacgcca aagacagaga aggagatacc ccgttgcatg     1020

atgcggtgag actgaaccgc tataagatga tccgactcct gattatgtat ggcgcggatc     1080

tcaacatcaa gaactgtgct gggaagacgc cgatggatct ggtgctacac tggcagaatg     1140

gaaccaaagc aatattcgac agcctcagag agaactccta caagacctct cgcatagcta     1200

cattctgagg caaacgacag actcttaatc agtaaatgtt cactggcatt ttgaaggcat     1260

ggcccaagag aagagacact agccataaaa tctagtttct atttatcaac gtgttgtgaa     1320

gatgtaccta atgaagtttt gagaaagcac agggttatag gtgtttaaat ttcctttagt     1380

gaaactctta tttattttta tgtattcctg tttatttatt tactgccacg ctactgatat     1440

tcagaccttc atgatcatcc atctggtgag cagagcttca tttgtatata acactttcag     1500

agccttccca cccataggta gttcttaaac caggtgaaag agcaaagttc aagtgcctac     1560

ttatgtgtca ttcgctcatg taagagtttt taagagaggg ctgattatca cagccctctt     1620

ttctcctgaa tttttaatgc agaagtttga atgaagcaag ggaaggcatg tagggacagg     1680

aaaggaaaca atggaaggaa agtgattctg tgaaaaggac agtgaagcca gctattttac     1740

ccccaggctg gatttttttt tttttttttt tttttttttt ttaccgagta cacagagtac     1800

ccaagtgaag agaacgtcat gagtgtaagt gcaaatcagt ggaaggagcg gcaaactggg     1860

acatgcagaa ttgaatttgc tcaaaaaaga tgaaaggaaa tgcaaactgt aaatgtataa     1920

atgtatattg tattgtatgt acattttata ttcataataa aggcaatcaa actcaaaaaa     1980

aaaaaaaaaa aaaa                                                       1994


<210>  932
<211>  4525
<212>  DNA
<213>  homo sapiens

<400>  932
tttgggaaag tgtggtggtg ggtgcgcgct cgcggcggag ggtaaacatt cgacagtccc       60

cgctctgaga gggagggaca gagagcgaac tgtcagatcg gagcgagagc gggcgcccga      120

gagagggaga gagagagagg gagggagagg aaaagtgaga gagggaaaga gagcgcgaac      180

gagggcgcag agcgagctcc tgctgcaact ctgctccagc acggccagcg ccagcgcccg      240

ccgtcggtgc actctacgag ccgtgcagcg tgcccactgg agttgttgtg tatcaaggat      300

cgatccccta tatgcacaca cacacctcca cctccaccaa tgcactcttc ttcctcctcc      360

ttctccagac aactgctggg aaaaaaataa aacaccaacc ccaaccgtca gcaacaaggt      420

aacagagcga ttcgacatca ttttttttcc tgttcaattt tttccttgtt atatttgttt      480

cctaatttct gcccaaaagg aaagatgtcg catcagactg tgactgttgc gaggagaatg      540

aaaaaggact cttgtttcag aggcaaccaa gagctccggc aatagcaact tcagagaaat      600

gcaccatcgc aagaagtttt cctaggacag aacaaaactt gaaacgagag gaccagaggg      660

ggagagcagg agccagcctc ccctctccgc actcgcgagc agccagcagc accacgcctt      720

caaggacgaa aaagttttac tactctaagg gaaaacgagt gaaatgtgtt cctgaggagg      780

agaggagagg agaggagaga gcggacaaga gaaggagcgg gccggttgct ggtcatccgt      840

aatttggcta aggaagaaag gagcagcttc tttctttgtt atctcccgtg aaaccttcac      900

ttagcaggtg gacggagccc cgcgaccggg cagagtccgg gctcgcccga ggacaggagg      960

aggagcggga gcccgcgcgt cccgggagag cgccccgagt gcaggtcccc gccccgcccg     1020

gcgagccccg ctggagcgag cccagcgcgc cggggctggg gggcggccac gaccccccct     1080

gaagggggtg gccacggagc gcaccccgag aagcgagccc ccctccccag agcgctgctc     1140

ctgcggctgc tgctgctgct ggtgaccaag gccggccggc gacccccgcg ccctgccgag     1200

cggccttgca gctgcagccg ggggccgcgg cggcggcggc ggcggcgggg gcggaggcgg     1260

cggcggagga ggaggcggcg aaggcggcgg ggccggcggg ggcccggggc gggggcgggg     1320

aaggaggggg ggaggaggcg ggaggcgggg ggcgcggcgg cggcggcggc ggcggcggcc     1380

gcggctgctg ctgcggcggc ggcggcggtg gtggcggcgg tggggtggcg ggagcggagc     1440

ggcatggcca cggcggcttc taacccctac ctgccgggga acagcctgct cgcggccggc     1500

tctattgtgc actcggacgc ggcaggggct ggcggcggcg ggggtggcgg cggcggcggc     1560

ggcgggggcg gcgcaggggg cgggggcggc ggcatgcagc cgggcagcgc cgccgtgacc     1620

tcgggcgcct accgggggga cccgtcctct gtcaagatgg tccagagcga cttcatgcag     1680

ggggccatgg ccgccagcaa cggcggccat atgctgagcc acgcgcacca gtgggtcaca     1740

gccctgcccc acgccgccgc cgccgccgcc gctgccgccg ccgccgccgt ggaggcgagc     1800

tcgccgtggt cgggcagcgc cgtgggcatg gctggcagcc cccagcagcc accgcagccg     1860

ccgccgccac cgccgcaggg ccccgacgtg aagggcggcg ccgggcgcga cgacctgcac     1920

gcgggcacag cgctgcacca ccgcgggccg ccgcacctcg gacccccgcc gccgccccca     1980

caccagggcc accctggggg ctggggggcg gccgccgctg ccgcagccgc agccgccgcc     2040

gccgccgccg ccgcgcacct cccgtccatg gccgggggcc agcagccgcc gccgcagagt     2100

ctgctctact cgcagcccgg aggcttcacg gtgaacggca tgctgagcgc gccaccgggg     2160

cccggcggcg gcggcggcgg cgcgggcggt ggagcccaga gcttggtgca cccggggctg     2220

gtgcgcgggg acacgccaga gctggccgag caccaccacc accaccacca ccacgcgcat     2280

cctcacccgc cgcacccgca ccacgcgcag ggacccccgc accacggcgg cggcggcggc     2340

ggcgcggggc ctggactcaa cagccacgac ccgcactcgg acgaggacac gccgacgtcg     2400

gacgacctgg agcagttcgc caagcagttc aagcagcggc gcatcaagct gggcttcacg     2460

caggccgacg tggggttggc gctgggcaca ctctacggca acgtgttctc gcagaccacc     2520

atctgccgct tcgaggccct gcagctgagc ttcaagaaca tgtgcaagct caagccgctg     2580

ctgaacaagt ggctggagga ggcggactca agcaccggca gccccacaag catcgacaag     2640

atcgcggcgc agggccgcaa gcgcaagaag cggacctcta tcgaggtgag cgtcaagggc     2700

gcgctggaga gccacttcct caagtgcccc aagccctccg cgcaggagat caccaacctg     2760

gccgacagcc tgcagctcga gaaggaggtg gtgcgggtct ggttctgcaa tcggcgccaa     2820

aaggagaagc gcatgacgcc gcccgggatc caacagcaga cgcccgacga cgtctactcg     2880

caggtgggca ccgtgagcgc cgacacgccg ccgcctcacc acgggctgca gacgagcgtt     2940

cagtgaagcc agggcgcaga gcgaagaggg ccgccgccgc cgccgcctcc gcagccgccg     3000

tcagcaccgc cgccgcccct gccgccgccg ccgccgccgc cgccgccgct gccgccgccg     3060

cgccgaccct gcacctgggc cgctccgggc tccagcccag gcccatccgc cgccctcccc     3120

tccacccaga gacaggcatg cccgcccttg gaggagaaaa cgcgggagaa acggaccaag     3180

gaggcatttt tgcagtccaa ggaaggaggg gccaaaaaat aaaaagcata ataaacaccc     3240

agactgtttt gtatacatat ataacaaaca aaaccggaag agaaaaaggg ggcgatcatg     3300

agatctcgtt catactgtgg tggtgtttcg tttttgtttt tgtttttaaa gaagggtgaa     3360

gatgcctgac gcacgaaaac tgcactcgtg aggtttttcc accctgagat gacctacacg     3420

gcagcggtgg acagcacctg cctcgtcttc tcctctttga aaaaaagaga gagagagagt     3480

cccctttcct ttcactttct ccctccaaaa cagctgccta aagagatcca cggaaacttt     3540

atttcctggg agcgacctga gagaaaacag aggcaccagg ttccatcagg ggacgacacc     3600

gtgctctggg accctgtttt tcttggccat attaaagtca tttggaaaca aatcaactct     3660

gaaatgggaa ggagggggga aaaacagtct ccaagaaaaa aataattata ttgacagctt     3720

ctgaaactaa cagactgaat agcaaagcca aaagaaaagt atcctcaaag taaccttgga     3780

aataaaagga tcgggaagga gcagagggag agggggaacg tccgctgagg agtggcgaga     3840

ggccccggcc gagtcgggtc gcgggcgggc gggcgaactg ggagcagagc gggggcccag     3900

ccagcgaggc cgccgagcca ggcccggccg cgtacccagg ctttgacggc tgccattcag     3960

ggtggacgat gcctaaagat tccaccgcta atattttttt tattaatatt ttttattttt     4020

tatttctgga ctgactcaga taaaggaatt tagaaagact gagcaccagc cgctgcactt     4080

ctctggactt ctctcctcaa tccgttgcca actttgattg aatgggtgct gtggatgtga     4140

ttatataata ctgccatttc caagcagtgt ttttggtagg ttttaataaa cagacttttc     4200

aaaagacggc aatatagaat tgttagatcc gttgttgatc taaaaatatt tgctttatat     4260

tttcattaaa tgacttcttt taatatttta ttcagaatac ttatgaactg ctgcaaaacg     4320

gtaatttatt tttccccaga tcttgtatta cgtgtttttt tcagacgagc acaaatcaaa     4380

atgaaatgaa aatatggaca gttgttaggt aataagggta tcttttgatg tgatcatttg     4440

attgtaattt aatttgagta gtgattccgt aagagctgat cgagaaaata aatttgttag     4500

aatgaaaaaa aaaaaaaaaa aaaaa                                           4525


<210>  933
<211>  412
<212>  DNA
<213>  homo sapiens

<400>  933
acagtgggca gcccgatttt ctgctgagta ggcgctgtga tttcagaatg tctgggcgag       60

gtaaaggtgg caaggggctg ggtaagggag gcgccaagcg ccaccggaag gtgctgcggg      120

acaatatcca aggcattaca aagccggcga ttcgccgtct cgcccgacgt gggggcgtca      180

agcgcatttc tggtctcatc tacgaggaga cccggggagt cctcaaagtc ttcctggaga      240

acgtgatccg tgacgcggtg acttacacgg agcacgccaa gcgcaagacc gtcacggcca      300

tggatgtggt gtacgcgctg aaacgccagg gtcgcaccct ttatggtttc ggcggttgag      360

ctgtccccac agcttctcta cagactccaa aaggcccttt tcagggcccc ca              412


<210>  934
<211>  4150
<212>  DNA
<213>  homo sapiens

<400>  934
cttgaatctt ggggcaggaa ctcagaaaac ttccagcccg ggcagcgcgc gcttggtgca       60

agactcagga gctagcagcc cgtccccctc cgactctccg gtgccgccgc tgcctgctcc      120

cgccacccta ggaggcgcgg tgccacccac tactctgtcc tctgcctgtg ctccgtgccc      180

gaccctatcc cggcggagtc tccccatcct cctttgcttt ccgactgccc aaggcacttt      240

caatctcaat ctcttctctc tctctctctc tctctctctc tctctctctc tctctctctc      300

tctctctctc gcagggtggg gggaagagga ggaggaattc tttccccgcc taacatttca      360

agggacacaa ttcactccaa gtctcttccc tttccaagcc gcttccgaag tgctcccggt      420

gcccgcaact cctgatccca acccgcgaga ggagcctctg cgacctcaaa gcctctcttc      480

cttctccctc gcttccctcc tcctcttgct acctccacct ccaccgccac ctccacctcc      540

ggcacccacc caccgccgcc gccgccaccg gcagcgcctc ctcctctcct cctcctcctc      600

ccctcttctc tttttggcag ccgctggacg tccggtgttg atggtggcag cggcggcagc      660

ctaagcaaca gcagccctcg cagcccgcca gctcgcgctc gccccgccgg cgtccccagc      720

cctatcacct catctcccga aaggtgctgg gcagctccgg ggcggtcgag gcgaagcggc      780

tgcagcggcg gtagcggcgg cgggaggcag gatgagcgca cgcggtgagg gcgcggggca      840

gccgtccact tcagcccagg gacaacctgc cgccccagcg cctcagaaga gaggacgcgg      900

ccgccccagg aagcagcagc aagaaccaac cggtgagccc tctcctaaga gacccagggg      960

aagacccaaa ggcagcaaaa acaagagtcc ctctaaagca gctcaaaaga aagcagaagc     1020

cactggagaa aaacggccaa gaggcagacc taggaaatgg ccacaacaag ttgttcagaa     1080

gaagcctgct caggaggaaa ctgaagagac atcctcacaa gagtctgccg aagaggacta     1140

gggggcgcca acgttcgatt tctacctcag cagcagttgg atcttttgaa gggagaagac     1200

actgcagtga ccacttattc tgtattgcca tggtctttcc actttcatct ggggtggggt     1260

ggggtggggt gggggagggg ggggtggggt ggggagaaat cacataacct taaaaaggac     1320

tatattaatc accttctttg taatcccttc acagtcccag gtttagtgaa aaactgctgt     1380

aaacacaggg gacacagctt aacaatgcaa cttttaatta ctgttttctt ttttcttaac     1440

ctactaatag tttgttgatc tgataagcaa gagtgggcgg gtgagaaaaa ccgaattggg     1500

tttagtcaat cactgcactg catgcaaaca agaaacgtgt cacacttgtg acgtcgggca     1560

ttcatatagg aagaacgcgg tgtgtaacac tgtgtacacc tcaaatacca ccccaaccca     1620

ctccctgtag tgaatcctct gtttagaaca ccaaagataa ggactagata ctactttctc     1680

tttttcgtat aatcttgtag acacttactt gatgattttt aactttttat ttctaaatga     1740

gacgaaatgc tgatgtatcc tttcattcag ctaacaaact agaaaaggtt atgttcattt     1800

ttcaaaaagg gaagtaagca aacaaatatt gccaactctt ctatttatgg atatcacaca     1860

tatcagcagg agtaataaat ttactcacag cacttgtttt caggacaaca cttcattttc     1920

aggaaatcta cttcctacag agccaaaatg ccatttagca ataaataaca cttgtcagcc     1980

tcagagcatt taaggaaact agacaagtaa aattatcctc tttgtaattt aatgaaaagg     2040

tacaacagaa taatgcatga tgaactcacc taattatgag gtgggaggag cgaaatctaa     2100

atttcttttg ctatagttat acatcaattt aaaaagcaaa aaaaaaaaag gggggggcaa     2160

tctctctctg tgtctttctc tctctctctt cctctccctc tctcttttca ttgtgtatca     2220

gtttccatga aagacctgaa taccacttac ctcaaattaa gcatatgtgt tacttcaagt     2280

aatacgtttt gacataagat ggttgaccaa ggtgcttttc ttcggcttga gttcaccatc     2340

tcttcattca aactgcactt ttagccagag atgcaatata tccccactac tcaatactac     2400

ctctgaatgt tacaacgaat ttacagtcta gtacttatta catgctgcta tacacaagca     2460

atgcaagaaa aaaacttact gggtaggtga ttctaatcat ctgcagttct ttttgtacac     2520

ttaattacag ttaaagaagc aatctcctta ctgtgtttca gcatgactat gtatttttct     2580

atgttttttt aattaaaaat ttttaaaata cttgtttcag cttctctgct agatttctac     2640

attaacttga aaatttttta accaagtcgc tcctaggttc ttaaggataa ttttcctcaa     2700

tcacactaca catcacacaa gatttgactg taatatttaa atattaccct ccaagtctgt     2760

acctcaaatg aattctttaa ggagatggac taattgactt gcaaagacct acctccagac     2820

ttcaaaagga atgaacttgt tacttgcagc attcatttgt tttttcaatg tttgaaatag     2880

ttcaaactgc agctaaccct agtcaaaact atttttgtaa aagacatttg atagaaagga     2940

acacgttttt acatactttt gcaaaataag taaataataa ataaaataaa agccaacctt     3000

caaagaaact tgaagctttg taggtgagat gcaacaagcc ctgcttttgc ataatgcaat     3060

caaaaatatg tgtttttaag attagttgaa tataagaaaa tgcttgacaa atattttcat     3120

gtattttaca caaatgtgat ttttgtaata tgtctcaacc agatttattt taaacgcttc     3180

ttatgtagag tttttatgcc tttctctcct agtgagtgtg ctgacttttt aacatggtat     3240

tatcaactgg gccaggaggt agtttctcat gacggctttt gtcagtatgg cttttagtac     3300

tgaagccaaa tgaaactcaa aaccatctct cttccagctg cttcagggag gtagtttcaa     3360

aggccacata cctctctgag actggcagat cgctcactgt tgtgaatcac caaaggagct     3420

atggagagaa ttaaaactca acattactgt taactgtgcg ttaaataagc aaataaacag     3480

tggctcataa aaataaaagt cgcattccat atctttggat gggcctttta gaaacctcat     3540

tggccagctc ataaaatgga agcaattgct catgttggcc aaacatggtg caccgagtga     3600

tttccatctc tggtaaagtt acacttttat ttcctgtatg ttgtacaatc aaaacacact     3660

actacctctt aagtcccagt atacctcatt tttcatactg aaaaaaaaag cttgtggcca     3720

atggaacagt aagaacatca taaaattttt atatatatag tttatttttg tgggagataa     3780

attttatagg actgttcttt gctgttgttg gtcgcagcta cataagactg gacatttaac     3840

ttttctacca tttctgcaag ttaggtatgt ttgcaggaga aaagtatcaa gacgtttaac     3900

tgcagttgac tttctccctg ttcctttgag tgtcttctaa ctttattctt tgttctttat     3960

gtagaattgc tgtctatgat tgtactttga atcgcttgct tgttgaaaat atttctctag     4020

tgtattatca ctgtctgttc tgcacaataa acataacagc ctctgtgatc cccatgtgtt     4080

ttgattcctg ctctttgtta cagttccatt aaatgagtaa taaagtttgg tcaaaacaga     4140

aaaaaaaaaa                                                            4150


<210>  935
<211>  1539
<212>  DNA
<213>  homo sapiens

<400>  935
cttgaatctt ggggcaggaa ctcagaaaac ttccagcccg ggcagcgcgc gcttggtgca       60

agactcagga gctagcagcc cgtccccctc cgactctccg gtgccgccgc tgcctgctcc      120

cgccacccta ggaggcgcgg tgccacccac tactctgtcc tctgcctgtg ctccgtgccc      180

gaccctatcc cggcggagtc tccccatcct cctttgcttt ccgactgccc aaggcacttt      240

caatctcaat ctcttctctc tctctctctc tctctctctc tctctctctc tctctctctc      300

tctctctctc gcagggtggg gggaagagga ggaggaattc tttccccgcc taacatttca      360

agggacacaa ttcactccaa gtctcttccc tttccaagcc gcttccgaag tgctcccggt      420

gcccgcaact cctgatccca acccgcgaga ggagcctctg cgacctcaaa gcctctcttc      480

cttctccctc gcttccctcc tcctcttgct acctccacct ccaccgccac ctccacctcc      540

ggcacccacc caccgccgcc gccgccaccg gcagcgcctc ctcctctcct cctcctcctc      600

ccctcttctc tttttggcag ccgctggacg tccggtgttg atggtggcag cggcggcagc      660

ctaagcaaca gcagccctcg cagcccgcca gctcgcgctc gccccgccgg cgtccccagc      720

cctatcacct catctcccga aaggtgctgg gcagctccgg ggcggtcgag gcgaagcggc      780

tgcagcggcg gtagcggcgg cgggaggcag gatgagcgca cgcggtgagg gcgcggggca      840

gccgtccact tcagcccagg gacaacctgc cgccccagcg cctcagaaga gaggacgcgg      900

ccgccccagg aagcagcagc aagaaccaac cggtgagccc tctcctaaga gacccagggg      960

aagacccaaa ggcagcaaaa acaagagtcc ctctaaagca gctcaaaaga aagcagaagc     1020

cactggagaa aaacggccaa gaggcagacc taggaaatgg gacaatctac taccaagaac     1080

cagctccaag aagaaaacat ctctgggaaa cagtaccaaa aggagtcact gaattgtcat     1140

tggaggagtc caggatagct cttcatgtta ttttcacctt gaggaattgt ccattacatc     1200

tatgagcctt atgtgtggct ttctccgata tagaaaccta tcaggtgtct tttagatcat     1260

ttcaaaacac tggcttattc tttcttatgt ttccaactga agtctgcatc ccaagatgta     1320

gtttcactgc taccccatat ggcacccttg tacgaatttg aaaaaagtac tcactctagg     1380

cacatgcaga gccatgcctg cggggacagc ttagagagta gagggtgggc tgaactccag     1440

ttactctcgt acagggatcc acctttttgc agaaatcaca gtgtggctat ggtgtggttt     1500

gatttcataa aacagatgct taaaaagtaa aaaaaaaaa                            1539


<210>  936
<211>  3571
<212>  DNA
<213>  homo sapiens

<400>  936
gctggccaat caggcggctc tcgtggaggc agctagcgcg aggctgggga gcgctgagcc       60

gcgcgtcgtg ccctgcgctg cccagactag cgaacaatac agtcaggatg gctaaaggtg      120

accccaagaa accaaagggc aagatgtccg cttatgcctt ctttgtgcag acatgcagag      180

aagaacataa gaagaaaaac ccagaggtcc ctgtcaattt tgcggaattt tccaagaagt      240

gctctgagag gtggaagacg atgtccggga aagagaaatc taaatttgat gaaatggcaa      300

aggcagataa agtgcgctat gatcgggaaa tgaaggatta tggaccagct aagggaggca      360

agaagaagaa ggatcctaat gctcccaaaa ggccaccgtc tggattcttc ctgttctgtt      420

cagaattccg ccccaagatc aaatccacaa accccggcat ctctattgga gacgtggcaa      480

aaaagctggg tgagatgtgg aataatttaa atgacagtga aaagcagcct tacatcacta      540

aggcggcaaa gctgaaggag aagtatgaga aggatgttgc tgactataag tcgaaaggaa      600

agtttgatgg tgcaaagggt cctgctaaag ttgcccggaa aaaggtggaa gaggaagatg      660

aagaagagga ggaggaagaa gaggaggagg aggaggagga ggatgaataa agaaactgtt      720

tatctgtctc cttgtgaata cttagagtag gggagcgccg taattgacac atctcttatt      780

tgagaagtgt ctgttgccct cattaggttt aattacaaaa tttgatcacg atcatattgt      840

agtctctcaa agtgctctag aaattgtcag tggtttacat gaagtggcca tgggtgtctg      900

gagcaccctg aaactgtatc aaagttgtac atatttccaa acatttttaa aatgaaaagg      960

cactctcgtg ttctcctcac tctgtgcact ttgctgttgg tgtgacaagg catttaaaga     1020

tgtttctggc attttctttt tatttgtaag gtggtggtaa ctatggttat tggctagaaa     1080

tcctgagttt tcaactgtat atatctatag tttgtaaaaa gaacaaaaca accgagacaa     1140

acccttgatg ctccttgctc ggcgttgagg ctgtggggaa gatgcctttt gggagaggct     1200

gtagctcagg gcgtgcactg tgaggctgga cctgttgact ctgcaggggg catccattta     1260

gcttcaggtt gtcttgtttc tgtatatagt gacatagcat tctgctgcca tcttagctgt     1320

ggacaaaggg gggtcagctg gcatgagaat attttttttt tttaagtgcg gtagttttta     1380

aactgtttgt ttttaaacaa actatagaac tcttcattgt cagcaaagca aagagtcact     1440

gcatcaatga aagttcaaga acctcctgta cttaaacacg attcgcaacg ttctgttatt     1500

ttttttgtat gtttagaatg ctgaaatgtt tttgaagtta aataaacagt attacatttt     1560

taaaactctt ctctattata acagtcaatt tctgactcac agcagtgaac aaacccccac     1620

tccattgtat ttggagactg gcctccctat aaatgtggta gcttctttta ttactcagtg     1680

gccagctcac ttagggctga gatgaaggag agggctactt gaagctactg tgtgattttg     1740

tttgtgtctg agtggcattc agatgaagtc tggaggagtt aggagaacga cataggcaag     1800

gttcagcagc cttccaaggt ataggaaggt gggtgattag gactgaggct atctaggttt     1860

aacttttgtc ccacctccac cccctatttt gtggggccaa atgcattgct aaacagcaat     1920

ttcagagtgt atggtgtgtc aaaaattaag gccttattgt ttttctcttt cacccctacc     1980

ccccgtgctc ctggcacata tcacattatt tgtggtgccc aacatttggg gtcttgagcc     2040

tgctgctggt ctcctggatg ccagtgaggg tatgtgggat ggggtggtgg ggtaggggac     2100

ggtatccttt ttttgctcct acttggaaac accaaacacc ccaaggaaga tgataggctc     2160

catcttgggc cacctgagct atagggcagg ctaatggaat caaccatttc tgagcactaa     2220

atgtatcatg aaaagttgaa tggcctgctc ataagtttag ctcattcact ggaaatgtag     2280

attgatgttc aatgttaaac tggaaggagc ttggtttgtg tgtcagtggt tatattagtg     2340

ggtagtgtaa cattttatcc aggttggggt gaggggagat ggccacagta gcaagtggtg     2400

acactaaata ccattttgaa ggctgatgtg tatatacatc attactgtcc gtagcaatga     2460

aggatacagt actgtgttgt gggtgagtgt tgctattgcc cagcattaat atttgggtgt     2520

gtatgtttga ggctatgaaa cacgcaggag tgtttttgtg ctattaattt taagagaaag     2580

cagctttttc ttaaaattca ctgttgagaa acttgcatgt ctggaggcgg tgtcctctcc     2640

gccctgtcgg gtcctggatg agtacgagtt atggtcacgg tcacagcctg atctcttatg     2700

tgttcatagc cattcgctct cccatcagaa ctgtttgtcc tgaatgtgtt cctctagttc     2760

tagaaaatga ccactaattt aaaaaactcg gttgtgaggt ttgcccagag gcacttgttc     2820

cagaatttcc cctcctgctt cagccatgtc cttgtcactt ggcattctaa gctaaagctt     2880

tagcttccca attcgtgatg tgctaggcca agattcggga gctgttgcca gcctcgtcaa     2940

atatggaaga gaaacaacct gcggtcaaaa gggagtgatt tgttaagtgg tgcgcgtcta     3000

tctcataact agatgtacca accagggaag ggccaaggat ggaaaggggt aacttttgtg     3060

cttccaaagt agctaagcag aagtggggga gcagtttagc cagatgatct ttgattaggc     3120

aaacattgag ttttaaagag gctgtcaagt tgaggccact tggtccatta gctggggcag     3180

caagatcact actcaacgtt ttcacactgt ggcaagattg ctcttctagt ggaataatgc     3240

cctagtttct ctgagatgat gtaagtggca tgatgttacc taaggcttag gcttagcttg     3300

atttctgggc ccactgtctg tgttcttaag atgccaacct gttgcttttt tttttttttt     3360

cccccattta aaaggatagt acctactccc tctaaccacc tcaccccatt cttgaatgac     3420

attttatcct tcggaaagaa caaggctgtg atgtagtgac tattgtctgt gtctcctgtg     3480

tgtgtctgtt cttgtcacaa atgtatttgg ggacgttgga tgcattcatt ttctgtaata     3540

aagtttctta atcactcttc ccaaaaagta a                                    3571


<210>  937
<211>  3289
<212>  DNA
<213>  homo sapiens

<400>  937
cgcggagcgg aggccgaggc gagagcctgg cgctgtagga ctagaacgaa aggagtgagg       60

cgccgagagc ccagatacca ttttggcgtg agagctggtg gttggcaagg ccgcgggagt      120

gggaagcgtc cgccatgttc tgcgaaaaag ccatggaact gatccgcgag ctgcatcgcg      180

cgcccgaagg gcaactgcct gccttcaacg aggatggact cagacaagtt ctggaggaga      240

tgaaagcttt gtatgaacaa aaccagtctg atgtgaatga agcaaagtca ggtggacgaa      300

gtgatttgat accaactatc aaatttcgac actgttctct gttaagaaat cgacgctgca      360

ctgtagcata cctgtatgac cgcttgcttc ggatcagagc actcagatgg gaatatggta      420

gcgtcttgcc aaatgcatta cgatttcaca tggctgctga agaaatggag tggtttaata      480

attataaaag atctcttgct acttatatga ggtcactggg aggagatgaa ggtttggaca      540

ttacacagga tatgaaacca ccaaaaagcc tatatattga agtccggtgt ctaaaagact      600

atggagaatt tgaagttgat gatggcactt cagtcctatt aaaaaaaaat agccagcact      660

ttttacctcg atggaaatgt gagcagctga tcagacaagg agtcctggag cacatcctgt      720

catgaccatg cgccgaggca cttccaggct tcactcaact catggactcc tctgtactca      780

ctctctccac cactcccttc acctccctct ttgattttag aagctataga cattgtttaa      840

gataactaag aatacttggc taagaagtat aatttgctaa ctattaagga ctttcttttt      900

ttaatgttgt acactattct tcctactctt ttttggtttt ggttttgttt tgtagagact      960

gtctcactat gttgcccaag ctggtctcaa actcctggcc tcaagcagtc ctcccacctt     1020

agcttctcaa agtgttgaga tcacaggcgt gagccactgc acccggcccc tactcctttt     1080

tctaataagc tgtatctgta atcacagcat tcctacagtt gttacagtgt gttttttaaa     1140

tgaaagtaaa catggttaca tttgaatctc ttaaataagc agtcacttgg ctggacagga     1200

agaaggtaga tcctgtgtgt cttgttttct ggtcatgtgt attgtacaag ctagagagct     1260

gaatttctga gatacacatt ttcaaatcac atgcaagtga agatgatggt ctgtagaaat     1320

tttcagtata tataatgttt aatgacatac taatttatca tctggctatt tgggaaggaa     1380

ggacacacat ggattttgca catttccacc atggtggctg gtgtggcttg tggctatggg     1440

gtgatcacca gtatcaccac tttggaaggg gacagtgaaa ttggggctag agaaggaact     1500

ttgtacagtt ttccctgaga ttcagattga ctgaaaagtc acatgaagag ttgattgtct     1560

tttaatggta tgttttaaac agctgacatt ttaaattttg atgaaatcca gtttattcgt     1620

ttgttctttt atgctttggg tgttgcatcc gagaaatctt ttcccatccc aagatcacaa     1680

ttttttttcc tttttacttc tagaagtgtt ataattttaa gctttatact ttggtctatg     1740

acccgttttt ttttttgttt tgttttgttt tttcgtttgt ttctttgttt tgagatggag     1800

tcttgttctg tcacccaggc tggggtgcag tggcgtgatc ttggctcact gcaatctcta     1860

tcccctgggt tcaagtgatt ctcttgtctc agcctcccaa gtagctggga ttacaggcac     1920

aggccgccac gcctggctaa tttttgtatt tttagtagag acagagtttt accatgttgg     1980

ccaggctggt ttcaaactcc tgacctcaag tgacccacct tggcctccca aagttttggg     2040

attacaagtg tgggccaccg cggccagcct atgatccatt ttgaatgaat tttttatatg     2100

gtgcaaggtg tcaatccacc ttcacttttt cttgggaata tagatatcca gctgtttcac     2160

taccattttt tgaaaggact gccctttgct ctatcacctt tgcatttttg ttaaaaagta     2220

gttgtcaatg tatatgtggg tttatttcag gactctgttt tgttccattg acctgttttt     2280

ctctcctgaa tgccaatacc atatttgtat gtagtgtatg taattttcta ataattcttg     2340

aaacagatag tattaatgtg tcatattttt gctgttgttt gtattttttg tagagatggg     2400

gtttcaccgt gttggccagg ctgtgttgaa ctcctgagct aaagcaatac acttgcctcg     2460

tcctccccat gtgctgggat tacaggcgtg agccttggtg ctggcccagt gtaccacatt     2520

tctttttgag atttgttttg gctatgttaa gtcctttgct tttgatgtga aatttgggaa     2580

caggcagggt gtggtggctt atgcctgtaa tcctagaact ttgggaggcc tagatgggtg     2640

gatcacttga gctcaggagt tccagaccag cccgggccta tggcaaaact ccgtctctac     2700

aaaaaataga aaaaattagc caggtgtggt ggtgcatgcc tgtagtcaca gttacacggc     2760

aggctgaggt gggaggatca cttgaacccc agaggtcaag actgcagtga gctgagatca     2820

caccactgta ctccagcctg ggtgacaaag tgagactcta tctcaaaaag aaattaggat     2880

caatttgtca atttctacaa caacaacaac aaaaacccct gttgggcacc ttgattgaga     2940

ttgcattgaa tttatataaa actgttggga gaattgacat cttaataata ttgagtcttc     3000

tggcctataa acaaggtctg tcttcctagg tattaatgtt ttgtcttcta tttctcttaa     3060

taatcttttg tagttttcag tgtacaggtc taccatgtca gcatttcata gttttgatgc     3120

taaatggtat tttaaaattt caaattctaa ccacttgttg ctagtaaata gaaatacaat     3180

tgatgttgaa cttgtatcct tcagccttgc taaactgtga gttctcatgg tgtttttgta     3240

aattacatca acagtcatgt gttctatgaa taaagagttt tactccttc                 3289


<210>  938
<211>  3049
<212>  DNA
<213>  homo sapiens

<400>  938
ggcgagggtc ggggccaccg cgcggcgacc tcgggtcccg gagcgaccgc agggcagccc       60

cgggcgccgg ccccggtgcg cgtctcctgt gcgcgcccct ccgcgcgcgg ccccgatgct      120

ggacatgagc gaggcccgct cccagccgcc ctgcagcccg tccggcaccg ccagctccat      180

gtcgcacgtg gaggactcgg actcggacgc gccgccgtct cccgccggct ccgagggcct      240

gggccgcgcg ggggtcgcgg tggggggcgc ccggggcgac ccggcggagg cggcggacga      300

gcgcttcccg gcctgcatcc gcgacgccgt gtcgcaggtg ctcaagggct acgactggag      360

tctggtgccc atgccggtgc gcggcggcgg cggcggcgcg ctcaaagcca agccgcatgt      420

gaagcggccc atgaacgcat tcatggtgtg ggcgcaggcg gcgcgccgca agctggccga      480

ccagtacccg cacctgcaca acgccgagct cagcaagacg ctgggcaagc tgtggcgctt      540

gctgagcgag agcgagaagc ggcccttcgt ggaggaggca gagcgccttc gcgtgcagca      600

caagaaggac caccccgact acaagtacca gccacggcgc aggaagagcg ccaaagccgg      660

ccacagcgac tccgactcgg gcgcggagct gggaccccac cctggcggcg gtgccgtgta      720

caaggctgaa gcagggcttg gagatgggca ccaccatggc gaccacacag ggcagaccca      780

cgggccgccc accccgccca ccacccccaa gacggagctg cagcaggcgg gcgccaagcc      840

ggagctgaag ctggagggac gccggccggt ggacagcggg cgccagaaca tcgacttcag      900

caacgtggac atctcggagc tcagcagcga ggtcatgggc accatggacg ccttcgacgt      960

ccacgagttc gaccagtacc tgcccctggg cggccccgcc ccacccgagc cgggccaggc     1020

ctatgggggc gcctacttcc acgccggggc gtcccccgtg tgggcccaca agagtgcccc     1080

gtcggcctcc gcgtcgccca ccgagacggg tcccccacgg ccgcacatca agacggagca     1140

gccgagcccc ggccactacg gcgaccagcc ccgaggctcg cccgactacg gttcctgcag     1200

cggccagtcc agcgccaccc cggccgcccc cgccggcccc ttcgccggct cacagggcga     1260

ctatggcgac ctgcaggcct ccagctacta tggtgcctac cctggctacg cacccggcct     1320

ctaccagtac ccctgcttcc actcgccgcg ccggccctac gcctcacccc tgctcaacgg     1380

cctggccctg ccgcccgccc acagccccac cagtcactgg gaccagccgg tgtacaccac     1440

cctgaccagg ccctgagggc ccagccgcgg ggagggactc gcaggcgtca gggggcagcc     1500

ttgtcccggc ccagtgtgtg tgaccagggc gggaggggcc ccagtggctg agctccaagt     1560

gcctgctgaa gtctgcaggg aaacacgctt gctgcccgtg gccctcggcc tccagatggc     1620

cacacctctg ccgacgacgg accagctccc tctcccttct atctttcttt ttgaggtggt     1680

gggattattc cacaaagaag ggctgccgtt tggtccctct tccgtgagga ctggcggcac     1740

cagcaccttc gctttgcatc tcggtagagg agaaacggca gcacagccca aggaccaaag     1800

gagggggtgg caggggcctt gcagggcgct gtgaggtcca ggccggtctt ggcgccgaga     1860

gcccctgcac tcaaggccac attccctcga caacggctgc acgggctgtc cgggatccgg     1920

ggtgtctgtc cgcagactgg gatgagtcta ctcgagcatc tccgggacct gcctgtcaga     1980

tctgaggtgt ctccttgctg gcagagtgcg ctcacgcgag ggctggctgt gatgaacaca     2040

tctctctttt atttttatgt ttttgataat ttttattttt gaagcttaaa tgtgtttctt     2100

ctgaaagctg ttaaagatgt atttatgttc tgtgttattt tatctttaat taatgaggta     2160

attcgggcaa agagtagaat ttaagacaaa acggaagctg ggaagcttcc cttgagggca     2220

ggcaggaggt ggagttgcag ctgttggccg gcatcacgtt gctcgttgct cggcttatgg     2280

gaggccgccc tggagggccc ggaggtccca aggtccctgg gaggactggg cccctcatgc     2340

ctcgagcttg gcaaccgaaa acccgaggga ggagaaggga cctgccttgt gacatctctg     2400

atcaggttgg ggtgccccag cacccagtac cagtttgggg tttgggaagc aggactccgt     2460

ccctgtcccc gactgtgcca cgtggtagga cacataggac acaggaattc ctgggtcctt     2520

gcccatgact gtgccatgtg gtaggacaca ggacacagga attcctggaa agtggtggct     2580

tcagaagtga tcttggctcg caggcaccag tgccacctac caagctgtga aactaaacct     2640

tctccactaa acgtcgttag ggcctcagtt ctagacgagt catacctgat tcacctgcac     2700

tgcttcccct gtgtgctgag catagagcat acaatagcgc ctacttcacg gaaacttgtg     2760

cctttaaact ttgtaaactt aaacacagcc gagaagttgc ttctttgtac tttttctact     2820

tttcctactt ttttgtagaa aaaaaagata atgcctctgc ttctatttct ctgggggtgg     2880

gggtgggggc cgggagccgt cgcagacccg tttcatgcag cgtctccctt ggcaccgcgt     2940

tcggaggacg caccctcact cccctgctgc cttcactcct ttctgaccaa gcaacgctaa     3000

cttttgtaca gatcgatttg ataaaattaa acaaagtgct ttttatgga                 3049


<210>  939
<211>  2078
<212>  DNA
<213>  homo sapiens

<400>  939
atgtcctatc cgcagggcta cttgtaccag ccgtccgcct cgctggcgct ctactcgtgc       60

ccggcgtaca gcaccagcgt catttcgggg ccccgcacgg atgagctcgg ccgctcttct      120

tcgggctccg cgttctcgcc ctacgctggc tcgactgcct tcacggcgcc ctcgccgggc      180

tacaactcgc acctccagta cggcgccgac cccgcggccg ccgccgccgc cgccttctcc      240

tcgtacgtgg gctctcccta cgaccacaca cccggcatgg cgggctcctt ggggtaccat      300

ccttacgcgg cgcccctggg atcgtaccct tacggggacc cagcgtaccg gaagaacgcc      360

acaagggacg ccacggctac cctcaaggcc tggctcaacg agcaccgcaa gaacccctac      420

cccaccaagg gcgagaagat catgctggcc atcatcacca agatgaccct cacccaggtg      480

tccacctggt tcgccaacgc gcgccggcgc ctcaagaaag agaataaaat gacgtggacg      540

ccgcggaacc gcagcgagga cgaggaagag gaggagaaca ttgacctgga gaagaacgac      600

gaggacgagc cccagaagcc cgaggacaag ggcgaccccg agggccccga agcaggagga      660

gctgagcaga aggcggcttc gggctgcgaa cggcttcagg gaccacccac ccctgcaggc      720

aaggagacgg agggcagcct cagcgactcg gattttaagg agccgccctc ggagggccgc      780

ctcgacgcgc tgcagggccc cccccgcacc ggcgggccct ccccggctgg gccagcggcg      840

gcgcggctgg cggaggaccc ggcccctcac taccccgccg gagcgccggc gcccggcccg      900

catccagccg cgggcgaggt gcctccgggt cccggcgggc cctcggttat ccattcgccg      960

cctccgccgc cgcctcctgc ggtgctcgcc aagcccaaac tgtggtcttt ggcagagatc     1020

gccacatcgt cggacaaggt caaggacggg ggcggcggga acgagggctc tccatgccca     1080

ccgtgtcccg ggcccatagc cgggcaagcc ctaggaggca gccgggcgtc gccggccccg     1140

gcgccgtcac gctcgccctc ggcgcagtgt ccttttccag gcgggacggt gctgtcccgg     1200

cctctctact acaccgcgcc cttctatccc ggctacacga actatggctc cttcggacac     1260

cttcatggcc acccggggcc cgggccaggc cccacaaccg gtccggggtc tcatttcaat     1320

ggattaaacc agaccgtgtt gaaccgagcg gacgctttgg ctaaagaccc gaaaatgttg     1380

cggagccagt ctcagctaga cctgtgcaaa gactctccct atgaattgaa gaaaggtatg     1440

tccgacattt aacgcgggct gcgtcggtcc cggacttttc taatttatta aaaacatggc     1500

cttggcagtt atttttccat caccgagaga gagagacaga gagagaaaat aaactacccc     1560

tcctattcag aagtttatag tttatggaga tggatgacat aaaaatgtaa acatctccac     1620

acaaaaaaaa aaatgtctta accaaccgaa aagaaaaatt aaaaaaggat ttgtattaaa     1680

tcttattctg tatatttaat gtagcatttt tgtatttaaa ttgataattc aatatctttg     1740

aagtaaatta tgaaatcaag acacctgtac aggcatttaa tgtttttttg taatataaat     1800

atatacattt gtgtttcccc caaaactgtt tcatagttaa aaaatacaag tttaatttaa     1860

ttttttacac ctattgattc tgctgggtat gagctaaagt attacagaaa ggaaacaggt     1920

tatactctta gatttaaaaa gtgaaagaaa ctgcaggcgc ctttgtaaaa tgcaaaatat     1980

ttaattaaaa gagattttaa cataatgaga gccactcatt actttttaga agcctcaata     2040

aactgtccat tgccttggtc aaaaaaaaaa aaaaaaaa                             2078


<210>  940
<211>  2078
<212>  DNA
<213>  homo sapiens

<400>  940
atgtcctatc cgcagggcta cttgtaccag ccgtccgcct cgctggcgct ctactcgtgc       60

ccggcgtaca gcaccagcgt catttcgggg ccccgcacgg atgagctcgg ccgctcttct      120

tcgggctccg cgttctcgcc ctacgctggc tcgactgcct tcacggcgcc ctcgccgggc      180

tacaactcgc acctccagta cggcgccgac cccgcggccg ccgccgccgc cgccttctcc      240

tcgtacgtgg gctctcccta cgaccacaca cccggcatgg cgggctcctt ggggtaccat      300

ccttacgcgg cgcccctggg atcgtaccct tacggggacc cagcgtaccg gaagaacgcc      360

acaagggacg ccacggctac cctcaaggcc tggctcaacg agcaccgcaa gaacccctac      420

cccaccaagg gcgagaagat catgctggcc atcatcacca agatgaccct cacccaggtg      480

tccacctggt tcgccaacgc gcgccggcgc ctcaagaaag agaataaaat gacgtggacg      540

ccgcggaacc gcagcgagga cgaggaagag gaggagaaca ttgacctgga gaagaacgac      600

gaggacgagc cccagaagcc cgaggacaag ggcgaccccg agggccccga agcaggagga      660

gctgagcaga aggcggcttc gggctgcgaa cggcttcagg gaccacccac ccctgcaggc      720

aaggagacgg agggcagcct cagcgactcg gattttaagg agccgccctc ggagggccgc      780

ctcgacgcgc tgcagggccc cccccgcacc ggcgggccct ccccggctgg gccagcggcg      840

gcgcggctgg cggaggaccc ggcccctcac taccccgccg gagcgccggc gcccggcccg      900

catccagccg cgggcgaggt gcctccgggt cccggcgggc cctcggttat ccattcgccg      960

cctccgccgc cgcctcctgc ggtgctcgcc aagcccaaac tgtggtcttt ggcagagatc     1020

gccacatcgt cggacaaggt caaggacggg ggcggcggga acgagggctc tccatgccca     1080

ccgtgtcccg ggcccatagc cgggcaagcc ctaggaggca gccgggcgtc gccggccccg     1140

gcgccgtcac gctcgccctc ggcgcagtgt ccttttccag gcgggacggt gctgtcccgg     1200

cctctctact acaccgcgcc cttctatccc ggctacacga actatggctc cttcggacac     1260

cttcatggcc acccggggcc cgggccaggc cccacaaccg gtccggggtc tcatttcaat     1320

ggattaaacc agaccgtgtt gaaccgagcg gacgctttgg ctaaagaccc gaaaatgttg     1380

cggagccagt ctcagctaga cctgtgcaaa gactctccct atgaattgaa gaaaggtatg     1440

tccgacattt aacgcgggct gcgtcggtcc cggacttttc taatttatta aaaacatggc     1500

cttggcagtt atttttccat caccgagaga gagagacaga gagagaaaat aaactacccc     1560

tcctattcag aagtttatag tttatggaga tggatgacat aaaaatgtaa acatctccac     1620

acaaaaaaaa aaatgtctta accaaccgaa aagaaaaatt aaaaaaggat ttgtattaaa     1680

tcttattctg tatatttaat gtagcatttt tgtatttaaa ttgataattc aatatctttg     1740

aagtaaatta tgaaatcaag acacctgtac aggcatttaa tgtttttttg taatataaat     1800

atatacattt gtgtttcccc caaaactgtt tcatagttaa aaaatacaag tttaatttaa     1860

ttttttacac ctattgattc tgctgggtat gagctaaagt attacagaaa ggaaacaggt     1920

tatactctta gatttaaaaa gtgaaagaaa ctgcaggcgc ctttgtaaaa tgcaaaatat     1980

ttaattaaaa gagattttaa cataatgaga gccactcatt actttttaga agcctcaata     2040

aactgtccat tgccttggtc aaaaaaaaaa aaaaaaaa                             2078


<210>  941
<211>  2590
<212>  DNA
<213>  homo sapiens

<400>  941
atttgcacct agaaatttta ggcaagtgat agctgcgtaa tcatactgcg gcaccgtttt       60

tttcttgcag cagtagctgc ttgcggagga ggtctgccca ctgcagctct ctgcagtctc      120

cggctctctc ctgcaggatc ggtcaacgca gccgtcgccg ccctctgcac ccagcccagg      180

tcgccactgc ttcagtccgg ttctcaaagc ctcagcacca tcttttatcc ccgagcagcc      240

tggatcgtcg ttccctcagt ccggacgcca ctgctaggtc cgaccaccgc cgcttctgat      300

atttcggtga gtcttttcct gtggaggttt ggtctcccga tctctgtggt agccacctta      360

ggcgtgtacg gtcctttgaa aaatggccga gtcagagaac cgcaaggagc tgtcagaatc      420

cagtcaagaa gaggctggta atcagataat ggtggaaggg ctcggggaac atctggagcg      480

cggtgaagat gccgctgctg ggcttggaga cgatgggaag tgcggtgaag aagctgccgc      540

tgggcttggg gaagaagggg aaaacggtga agatactgct gctgggtccg gggaagatgg      600

gaaaaaaggt ggcgatactg atgaggactc agaggcagac cgtccaaaag gacttatcgg      660

ttatgtttta gatacagact ttgttgaaag tctacctgtg aaagttaagt accgtgtgtt      720

agcccttaaa aagcttcaaa ctagagcggc caatttagaa tccaaattcc tgagggaatt      780

tcatgacatt gaaagaaagt ttgctgaaat gtaccaaccc ttactggaaa aaagacgtca      840

gatcatcaat gcaatctatg aacctacaga agaggaatgt gaatataaat cagactctga      900

ggactgtgat gatgaggaaa tgtgtcatga agagatgtat ggtaatgagg agggtatggt      960

acatgaatat gtggatgagg acgatggtta tgaggactat tattatgatt atgctgtgga     1020

agaggaggag gaggaggagg aggaggacga cattgaggct actggagaag agaataaaga     1080

agaggaggat cctaagggaa ttcctgattt ttggctaact gttttaaaaa acgttgatac     1140

actcactcct ttgattaaga aatatgatga gcctattctg aagctcctga cagatattaa     1200

agttaagctt tcagatcctg gcgagcccct cagtttcaca ctagaatttc acttcaaacc     1260

caatgaatat ttcaaaaatg agttgttgac aaagacctat gtgctgaagt caaagctagc     1320

atattatgat ccccatccct ataggggaac tgcgattgag tattccacag gctgtgagat     1380

agattggaat gaaggaaaga atgtcacttt gaaaaccatc aagaagaaac agaaacatcg     1440

gatctgggga acaatccgaa ctgtaactga agattttccc aaggattcat ttttcaattt     1500

tttctctcct catggaatca cctcaaatgg aagggatgga aatgatgatt ttttacttgg     1560

tcacaattta cgtacttaca taattccaag atcagtatta tttttctcag gtgatgcact     1620

ggaatctcag caggaggggg tagttagaga agttaatgat gcaatttatg acaaaattat     1680

ttatgataat tggatggctg caattgagga agttaaagct tgttgcaaaa accttgaggc     1740

attagtagaa gacattgatc gttagagcag agtatacatg gccctgaaat taactgccct     1800

agatatagtt actcaaggta taagaagcct tgtgttctgt atttttcttg tagtgttagt     1860

taaaacatat gtttcaaaaa tataagaaaa gttcaaaaac taattaattt gaccttgagt     1920

tttagtagta gaatgttttc aagaaatgta cactgtggta aatgatttaa aacactagta     1980

tagtgttgtg tagcttaatc cttctgaagt ctttttgtca tgtagctatt aatctgtggc     2040

tatgaaatga tcagaaatgc taagtgagat caatatttgt ttggaaaaaa aatcttggga     2100

aacaacccaa gggttttcgc tgttgttgtt tttctttttc tatttttgtt tacttagtcc     2160

tttagctagt ggatttaatt ttgttgtgcc tgcttcattt tgcaataaca atgcagtaga     2220

atttaaaact tggatgctta agaggcctgc atatagataa gaatttcagg caaaactaca     2280

tttattgtta ataacagctt gttcataggc tcttgtattt tatgtaactg tgataaataa     2340

tgaaacttag ttatattgag gttattgttt gtcggtgaag tgttagtcac agtattttca     2400

aaagtttgca catattgttc tgtgtaattg tgtaagccat aattacagtg tttaattctc     2460

ttttcctatt acatcattca ttgaaagtga tcactttacc attttgaaaa gatatttcgt     2520

gttctttcac tgcaaaataa aaagaataaa aatttcagag tgtctcatgt ttaaaaaaaa     2580

aaaaaaaaaa                                                            2590


<210>  942
<211>  2590
<212>  DNA
<213>  homo sapiens

<400>  942
atttgcacct agaaatttta ggcaagtgat agctgcgtaa tcatactgcg gcaccgtttt       60

tttcttgcag cagtagctgc ttgcggagga ggtctgccca ctgcagctct ctgcagtctc      120

cggctctctc ctgcaggatc ggtcaacgca gccgtcgccg ccctctgcac ccagcccagg      180

tcgccactgc ttcagtccgg ttctcaaagc ctcagcacca tcttttatcc ccgagcagcc      240

tggatcgtcg ttccctcagt ccggacgcca ctgctaggtc cgaccaccgc cgcttctgat      300

atttcggtga gtcttttcct gtggaggttt ggtctcccga tctctgtggt agccacctta      360

ggcgtgtacg gtcctttgaa aaatggccga gtcagagaac cgcaaggagc tgtcagaatc      420

cagtcaagaa gaggctggta atcagataat ggtggaaggg ctcggggaac atctggagcg      480

cggtgaagat gccgctgctg ggcttggaga cgatgggaag tgcggtgaag aagctgccgc      540

tgggcttggg gaagaagggg aaaacggtga agatactgct gctgggtccg gggaagatgg      600

gaaaaaaggt ggcgatactg atgaggactc agaggcagac cgtccaaaag gacttatcgg      660

ttatgtttta gatacagact ttgttgaaag tctacctgtg aaagttaagt accgtgtgtt      720

agcccttaaa aagcttcaaa ctagagcggc caatttagaa tccaaattcc tgagggaatt      780

tcatgacatt gaaagaaagt ttgctgaaat gtaccaaccc ttactggaaa aaagacgtca      840

gatcatcaat gcaatctatg aacctacaga agaggaatgt gaatataaat cagactctga      900

ggactgtgat gatgaggaaa tgtgtcatga agagatgtat ggtaatgagg agggtatggt      960

acatgaatat gtggatgagg acgatggtta tgaggactat tattatgatt atgctgtgga     1020

agaggaggag gaggaggagg aggaggacga cattgaggct actggagaag agaataaaga     1080

agaggaggat cctaagggaa ttcctgattt ttggctaact gttttaaaaa acgttgatac     1140

actcactcct ttgattaaga aatatgatga gcctattctg aagctcctga cagatattaa     1200

agttaagctt tcagatcctg gcgagcccct cagtttcaca ctagaatttc acttcaaacc     1260

caatgaatat ttcaaaaatg agttgttgac aaagacctat gtgctgaagt caaagctagc     1320

atattatgat ccccatccct ataggggaac tgcgattgag tattccacag gctgtgagat     1380

agattggaat gaaggaaaga atgtcacttt gaaaaccatc aagaagaaac agaaacatcg     1440

gatctgggga acaatccgaa ctgtaactga agattttccc aaggattcat ttttcaattt     1500

tttctctcct catggaatca cctcaaatgg aagggatgga aatgatgatt ttttacttgg     1560

tcacaattta cgtacttaca taattccaag atcagtatta tttttctcag gtgatgcact     1620

ggaatctcag caggaggggg tagttagaga agttaatgat gcaatttatg acaaaattat     1680

ttatgataat tggatggctg caattgagga agttaaagct tgttgcaaaa accttgaggc     1740

attagtagaa gacattgatc gttagagcag agtatacatg gccctgaaat taactgccct     1800

agatatagtt actcaaggta taagaagcct tgtgttctgt atttttcttg tagtgttagt     1860

taaaacatat gtttcaaaaa tataagaaaa gttcaaaaac taattaattt gaccttgagt     1920

tttagtagta gaatgttttc aagaaatgta cactgtggta aatgatttaa aacactagta     1980

tagtgttgtg tagcttaatc cttctgaagt ctttttgtca tgtagctatt aatctgtggc     2040

tatgaaatga tcagaaatgc taagtgagat caatatttgt ttggaaaaaa aatcttggga     2100

aacaacccaa gggttttcgc tgttgttgtt tttctttttc tatttttgtt tacttagtcc     2160

tttagctagt ggatttaatt ttgttgtgcc tgcttcattt tgcaataaca atgcagtaga     2220

atttaaaact tggatgctta agaggcctgc atatagataa gaatttcagg caaaactaca     2280

tttattgtta ataacagctt gttcataggc tcttgtattt tatgtaactg tgataaataa     2340

tgaaacttag ttatattgag gttattgttt gtcggtgaag tgttagtcac agtattttca     2400

aaagtttgca catattgttc tgtgtaattg tgtaagccat aattacagtg tttaattctc     2460

ttttcctatt acatcattca ttgaaagtga tcactttacc attttgaaaa gatatttcgt     2520

gttctttcac tgcaaaataa aaagaataaa aatttcagag tgtctcatgt ttaaaaaaaa     2580

aaaaaaaaaa                                                            2590


<210>  943
<211>  10017
<212>  DNA
<213>  homo sapiens

<400>  943
ttcctccgcg aaggctcctt tgatattaat agtgttggtg tcttgaaact gacgtaatgc       60

gcggagactg aggtcctgac aagcgataac atttctgata aagacccgat cttactgcaa      120

tctctagcgt cctctttttt ggtgctgctg gtttctccag acctcgcgtc ctctcgattg      180

ctctctcgcc ttcctatttc tttttttttt ttttaaacaa aaaacaacac cccctcccct      240

ctcccacccg gcaccgggca catccttgct ctatttcctt tctctttctc tctctctctc      300

tctctctctc ttttttaata agggtggggg agggaaaggg gggggaggca ggaaagacct      360

ttttctctcc cccccgcaat aatccaagat caactctgca aacaacagaa gacggttcat      420

ggctttggcc gccgcgccac catctttcgg gctgccgagg gtgttcttga cgattaatca      480

acagatgtac agatcagctc tcaaaatgtc ttctgtgtct tctgagcgtc ttctaagaca      540

attgcattag cctcctgcta gttgactaat agaattaata attgtaaaaa gcactctaaa      600

gccacatgcc ttatgaagtc aatgctgggt atgattttac aaatatggtc cggaaaaaga      660

acccccctct gagaaacgtt gcaagtgaag gcgagggcca gatcctggag cctataggta      720

cagaaagcaa ggtatctgga aagaacaaag aattttctgc agatcagatg tcagaaaata      780

cggatcagag tgatgctgca gaactaaatc ataaggagga acatagcttg catgttcaag      840

atccatcttc tagcagtaag aaggacttga aaagcgcagt tctgagtgag aaggctggct      900

tcaattatga aagccccagt aagggaggaa actttccctc ctttccgcat gatgaggtga      960

cagacagaaa tatgttggct ttctcatctc cagctgctgg gggagtctgt gagcccttga     1020

agtctccgca aagagcagag gcagatgacc ctcaagatat ggcctgcacc ccctcagggg     1080

actcactgga gacaaaggaa gatcagaaga tgtcaccaaa ggctacagag gaaacagggc     1140

aagcacagag tggtcaagcc aattgtcaag gtttgagccc agtttcagtg gcctcaaaaa     1200

acccacaagt gccttcagat gggggtgtaa gactgaataa atccaaaact gacttactgg     1260

tgaatgacaa cccagacccg gcacctctgt ctccagagct tcaggacttt aaatgcaata     1320

tctgtggata tggttactac ggcaacgacc ccacagatct gattaagcac ttccgaaagt     1380

atcacttagg actgcataac cgcaccaggc aagatgctga gctggacagc aaaatcttgg     1440

cccttcataa catggtgcag ttcagccatt ccaaagactt ccagaaggtc aaccgttctg     1500

tgttttctgg tgtgctgcag gacatcaatt cttcaaggcc tgttttacta aatgggacct     1560

atgatgtgca ggtgacttca ggtggaacat tcattggcat tggacggaaa acaccagatt     1620

gccaagggaa caccaagtat ttccgctgta aattctgcaa tttcacttat atgggcaact     1680

catccaccga attagaacaa cattttcttc agactcaccc aaacaaaata aaagcttctc     1740

tcccctcctc tgaggttgca aaaccttcag agaaaaactc taacaagtcc atccctgcac     1800

ttcaatccag tgattctgga gacttgggaa aatggcagga caagataaca gtcaaagcag     1860

gagatgacac tcctgttggg tactcagtgc ccataaagcc cctcgattcc tctagacaaa     1920

atggtacaga ggccaccagt tactactggt gtaaattttg tagtttcagc tgtgagtcat     1980

ctagctcact taaactgcta gaacattatg gcaagcagca cggagcagtg cagtcaggcg     2040

gccttaatcc agagttaaat gataagcttt ccaggggctc tgtcattaat cagaatgatc     2100

tagccaaaag ttcagaagga gagacaatga ccaagacaga caagagctcg agtggggcta     2160

aaaagaagga cttctccagc aagggagccg aggataatat ggtaacgagc tataattgtc     2220

agttctgtga cttccgatat tccaaaagcc atggccctga tgtaattgta gtggggccac     2280

ttctccgtca ttatcaacag ctccataaca ttcacaagtg taccattaaa cactgtccat     2340

tctgtcccag aggactttgc agcccagaaa agcaccttgg agaaattact tatccgtttg     2400

cttgtagaaa aagtaattgt tcccactgtg cactcttgct tctgcacttg tctcctgggg     2460

cggctggaag ctcgcgagtc aaacatcagt gccatcagtg ttcattcacc acccctgacg     2520

tagatgtact cctctttcac tatgaaagtg tgcatgagtc ccaagcatcg gatgtcaaac     2580

aagaagcaaa tcacctgcaa ggatcggatg ggcagcagtc tgtcaaggaa agcaaagaac     2640

actcatgtac caaatgtgat tttattaccc aagtggaaga agagatttcc cgacactaca     2700

ggagagcaca cagctgctac aaatgccgtc agtgcagttt tacagctgcc gatactcagt     2760

cactactgga gcacttcaac actgttcact gccaggaaca ggacatcact acagccaacg     2820

gcgaagagga cggtcatgcc atatccacca tcaaagagga gcccaaaatt gacttcaggg     2880

tctacaatct gctaactcca gactctaaaa tgggagagcc agtttctgag agtgtggtga     2940

agagagagaa gctggaagag aaggacgggc tcaaagagaa agtttggacc gagagttcca     3000

gtgatgacct tcgcaatgtg acttggagag gggcagacat cctgcggggg agtccgtcat     3060

acacccaagc aagcctgggg ctgctgacgc ctgtgtctgg cacccaagag cagacaaaga     3120

ctctaaggga tagtcccaat gtggaggccg cccatctggc gcgacctatt tatggcttgg     3180

ctgtggaaac caagggattc ctgcaggggg cgccagctgg cggagagaag tctggggccc     3240

tcccccagca gtatcctgca tcgggagaaa acaagtccaa ggatgaatcc cagtccctgt     3300

tacggaggcg tagaggctcc ggtgtttttt gtgccaattg cctgaccaca aagacctctc     3360

tctggcgaaa gaatgcaaat ggcggatatg tatgcaacgc gtgtggcctc taccagaagc     3420

ttcactcgac tcccaggcct ttaaacatca ttaaacaaaa caacggtgag cagattatta     3480

ggaggagaac aagaaagcgc cttaacccag aggcacttca ggctgagcag ctcaacaaac     3540

agcagagggg cagcaatgag gagcaagtca atggaagccc gttagagagg aggtcagaag     3600

atcatctaac tgaaagtcac cagagagaaa ttccactccc cagcctaagt aaatacgaag     3660

cccagggttc attgactaaa agccattctg ctcagcagcc agtcctggtc agccaaactc     3720

tggatattca caaaaggatg caacctttgc acattcagat aaaaagtcct caggaaagta     3780

ctggagatcc aggaaatagt tcatccgtat ctgaagggaa aggaagttct gagagaggca     3840

gtcctataga aaagtacatg agacctgcga aacacccaaa ttattcacca ccaggcagcc     3900

ctattgaaaa gtaccagtac ccactttttg gacttccctt tgtacataat gacttccaga     3960

gtgaagctga ttggctgcgg ttctggagta aatataagct ctccgttcct gggaatccgc     4020

actacttgag tcacgtgcct ggcctaccaa atccttgcca aaactatgtg ccttatccca     4080

ccttcaatct gcctcctcat ttttcagctg ttggatcaga caatgacatt cctctagatt     4140

tggcgatcaa gcattccaga cctgggccaa ctgcaaacgg tgcctccaag gagaaaacga     4200

aggcaccacc aaatgtaaaa aatgaaggtc ccttgaatgt agtaaaaaca gagaaagttg     4260

atagaagtac tcaagatgaa ctttcaacaa aatgtgtgca ctgtggcatt gtctttctgg     4320

atgaagtgat gtatgctttg catatgagtt gccatggtga cagtggacct ttccagtgca     4380

gcatatgcca gcatctttgc acggacaaat atgacttcac aacacatatc cagaggggcc     4440

tgcataggaa caatgcacaa gtggaaaaaa atggaaaacc taaagagtaa aaccttagca     4500

cttagcacaa ttaaatagaa ataggttttc ttgatgggaa ttcaatagct tgtaatgtct     4560

tatgaagacc tattaaaaaa atacttcata gagcctgcct tatccaacat gaaattccct     4620

tcttttgtta ttctttcttt tgatgagtag gttaccaaga ttaaaaagtg agataaatgg     4680

tcaatgagaa agaatggaag atggtaaaca atcacttttt aaaacctgtt aagtcaaaac     4740

catcttggct aatatgtact ggggaaataa tccataagag atatcaccag actagaatta     4800

atatatttat aaagaaagag accaaaactg tctagaattt gaaagggttt acatattatt     4860

atactaaagc agtactggac tggccattgg accatttgtt ccaaaaccca taaattgttg     4920

cctaaattta taatgatcat gaaaccctag gcagaggagg agaaattgaa ggtccagggc     4980

aatgaaagaa aaatggcgcc ctctcaattt agtcttctct cattggccat gtttcagatt     5040

ttgacctaga aatgcgagct gtggttaggc ttggttagag tgcagcaagc aacatgacag     5100

atggtggcac gctgttttta cccagccctg cctgtacata cacatgcaca ccctctctga     5160

tatttttgtc ctttagatgt tcaaatactc agtagtcctt ttgtttgcgg tttagattca     5220

ttttgtccac acatgtaccc attttaaaaa acaatgtcct cgatgcttct gtagtgattt     5280

cattttagcc aggtatttct ttcttgtgtg tgatgaacca gtatggattt gcttttctaa     5340

gcctcctgtt ggttactaat ctcacttggc acattataac taaaggaatc ccctcaattc     5400

aaaagcatag atggatacaa atgtcagacc gtgggtttaa tttgtttaga acacatggca     5460

tttcttcaca aggtaacctg ctgtatttat ttattttctt ttggttaaat ataatttcca     5520

aactttgtgg tcaggcagcg tctaaggtta cgttaccaca gactgacagt tggtatatgt     5580

accagccaat cccttcatta aatgtataca gatttagtta agtagcatta aataggattc     5640

ttagaagtat gtcctcatag aacttttaat acttaaggct ttgtaaaaac tatccatgaa     5700

gggaaagctc ctcagcataa ctgctcaggg aaatagggct aaataactga acattaaata     5760

attggttaaa ggtgctgtta gtcgagcctc aatgcttgct acaaggatgt atgtacaagg     5820

actgacttta ataatttgca ttatattgtc ccaaccagta gtttattttt tgccacggag     5880

atgtagaaga tattacaagc tactggatgc actgtcagat taacttattt cattaaagaa     5940

gttgggagaa caaataggaa aaaaaaaact tatttttcta gtaaatatta atgtattaca     6000

tttcaaataa tggtgcctga catattgaat aattattttc tacagtgtac gtatgcaaca     6060

aagatattcc atcatgcatt agagtcagtt ctggctctgc ctagctgttt acatttgcaa     6120

atgtagcaaa caaggtaatg aagcaactat ttctattgca gtagatatcc ttttgtgtgt     6180

gtgtgtgtgc attaaagttg taaacggtaa catgaaacaa atgaaagttc ttgctataat     6240

ggtatggaaa acaagaagga aatgaaaata tttttatgcc tacttaggaa aaaaagggta     6300

gcacttattc attccaagta cttttttttt tttaattttt aagctcttaa ctcacattgt     6360

tatgcttaag atgataaaca tatatcctct ttttattgct ttgtctatgt ttcatatgaa     6420

acatttcaga aattattttg ataagtgttg ctggaatctg caacgctgat ttttttttgc     6480

attctgtagt cgcatttgca ctccattttt acattaattc gcagttgctt tgtatcattg     6540

ttttgtttgg gttttgtttc tttttcacag tgccgggtct tcgtttctta aagttggatg     6600

gcaggtagag ttcaaccagt tcgtgactgt tgtagcgaat gaagttaaaa aaatgtcttt     6660

ctgatgttgt gttgtcattt tcatttttgc atttttttgt ttgcatatta aaaaaagaga     6720

aaagagaaag caagagacag aaatcaggac taagtcctct gcttcagttt cattgttaac     6780

gggccttatt ctgatctcac ctgtcgcgta gctctaatat tcacataaac tgaaataaag     6840

aagtggaatg aggagctttg acattcaaat tatgtgatgt aatttatctt ccttaggaat     6900

tttgatggat gcatctcaaa atgtatagcc agacttgaga ggtgacaatt aaagatctaa     6960

aaaagagagg agattccccc aaacaacaat atttaatttt cttagtaaaa agaataacag     7020

aatgcatcgt ggcaatcctt aagcaacatt atctatgtgg actgcttaaa tcagcaaaac     7080

accagaagtt tggttaactt gggcaatatg acaagtatta ctttttgggc aaaactactc     7140

attaagcaat ttctctagtg tgtcggacac aaataggttc tttatttttg gcatgtatgc     7200

ctttttattt tcattcaatt tttttttttt ctcagacaga catagtagta acgactagca     7260

ttggaaaata catatcacta ttcttggaat atttatggtc agtctacttt ttagtagaat     7320

atttttggat agcgttgaca cgatagatct tattccatac ttctttatta ttgataattt     7380

tattttcatt ttttgctttc attattatac atattttggt ggagaagagg ttgggctttt     7440

ttgaaagaga caaaaattta ttataacact aaacactcct tttttgacat attaaagcct     7500

ttattccatc tctcaagata tattataaaa tttatttttt taatttaaga tttctgaatt     7560

attttatctt aaattgtgat tttaaacgag ctattatggt acggaacttt ttttaatgag     7620

gaatttcatg atgatttagg aattttctct cttggaaaag gcttcccctg tgatgaaaat     7680

gatgtgccag ctaaaattgt gtgccattta aaaactgaaa atattttaaa attatttgtc     7740

tatattctaa attgagcttt ggatcaaact ttaggccagg accagctcat gcgttctcat     7800

tcttcctttt ctcactcttt ctctcatcac tcacctctgt attcattctg ttgtttggga     7860

tagaaaaatc ataaagagcc aacccatctc agaacgttgt ggattgagag agacactaca     7920

tgactccaag tatatgagaa aaggacagag ctctaattga taactctgta gttcaaaagg     7980

aaaagagtat gcccaattct ctctacatga catattgaga ttttttttaa tcaactttta     8040

agatagtgat gttctgttct aaactgttct gttttagtga aggtagattt ttataaaaca     8100

agcatgggga ttcttttcta aggtaatatt aatgagaagg gaaaaaagta tctttaacag     8160

ctctttgttg aagcctgtgg tagcacatta tgtttataat tgcacatgtg cacataatct     8220

attatgatcc aatgcaaata cagctccaaa aatattaaat gtatatatat tttaaaatgc     8280

ctgaggaaat acatttttct taataaactg aagagtctca gtatggctat taaaataatt     8340

attagcctcc tgttgtgtgg ctgcaaaaca tcacaaagtg accggtcttg agacctgtga     8400

actgctgccc tgtttagtaa ataaaattaa tgcatttcta gagggggaat atctgccatc     8460

cagtggtgga aatgtggagt aaagaagctg gtggtctgct tctgtgctgt atgccagcct     8520

tttgccttaa gttgagagga ggtcaacttt agctactgtc tttggtttga gagccatggc     8580

aaaaaaaaaa aaagaaaaaa agatcaagtc gtctttggtg agccagtaag gtgaaagctt     8640

gctgactgtc caaggcacaa gagaaaattg aggaattgaa atgcaacctg agtatcaaac     8700

taaatattct aatcaaaggt aggtactgtt aggtggaatt ctatcagcag gcaactgcaa     8760

atgagaagaa gatagaagga cgcccgtcgg gactttggag ggcattgtta ttttcccaaa     8820

gaaagacggc caagggcaga ggcatggatt ctttgcagag cacttccttt tggtttttca     8880

gtactgtttc atagacagtg ggctcacatg ttcctgatag tgctgcagtt gcttagaaag     8940

catcccagtt aattgcagta attagaactt ctggaatatg ctagggcaga agtatgtcaa     9000

gtatgtcaca tgaagaaaat gtgaaattca agagtaatcc acacgtgaga aactagacaa     9060

tgtacattca tgtgttctct tgaaaggaaa gggagagctg taagcttcac tctgtcctac     9120

accggagaaa agcaggaata actttaccgt ggaaataatg tttagctttt atcagagaaa     9180

attgtccttc tagagcatag agtcccaaaa ctcaattctg gttttcccct gttttttttt     9240

tttttttttt tcccaacata taaactgcag catatcactt tttctttttg tgcctcaggt     9300

tcctcagctg taaaattgaa aaatatatgt attaataata ttattaataa taataatggt     9360

aatgtagtac ttgtttgtaa agcactttga gatccttggt tgaaaggcac cataggagtg     9420

ccaagtatta ttatgtggcc aagggggtta tttaaactgt cagttcccaa aggccaggaa     9480

aggttggggt catttttctt aaagacgagc tgtaaatatc aactaggcag ccaatagtgt     9540

tgactatgaa gatgcaaaac tattactagg ctgataaaat catagtttct taatggctac     9600

caataaggca aatatcacaa taataaacgc caaattcctt agggcggact atttgacaac     9660

cacatggaaa actttggggg aggcatgagg ggggaacatc tcaaaatgcc aatgtaaaat     9720

ttaacttaca gcaatattca ccagcagaaa atgtctttca tatggaatga tttcatgttg     9780

ctaagaaaaa gaattcaatt tgtagtcctg atttgaatac tagaatgttg gctataatag     9840

ttctgttctt acaacacatg aaattttttc gttttatttt attttgtttt catagtgcat     9900

gttcatttct actcacaaac atgttcttgg tgtatttctt atgcaaacaa tcttcaggca     9960

gcaaagatgt ctgttacatc taaacttgaa taataaagtt ttaccaccag ttacaca       10017


<210>  944
<211>  11113
<212>  DNA
<213>  homo sapiens

<400>  944
ggctccgggg gtggcggtcg gacagtgtct agcacgctca gtccgggctt ggggccccgc       60

ggcggagaag gaggtagagg gggcggcggc ggcggcggcg gtggtggcgg caccatgttt      120

cttcactcag ttaatctctg gaacctggcg ttttatgtct tcatggtctt tctggcaacc      180

ctggggctgt gggatgtctt cttcggcttc gaggagaata agtgcagtat gagctacatg      240

tttgagtacc cggagtatca gaaaatagaa cttccaaaga aactggcaaa acgctatccc      300

gcatatgagt tgtatcttta tggagaggga tcctatgctg aagaacacaa aattctccct      360

ttgacgggta ttccagttct ctttcttcct ggtaatgctg gaagttataa gcaagttcgt      420

tctattggct ccattgcact tagaaaagca gaggacattg acttcaagta ccactttgac      480

ttctttagtg tgaacttcaa tgaagaactg gtggctttgt atggtggaag tcttcagaag      540

cagaccaagt ttgtacatga atgtattaaa acaattctca aactctataa gggtcaagaa      600

tttgctccaa aaagtgtggc aataattggt cattctatgg gtggccttgt tgcaagagca      660

ttgcttacac tgaaaaattt taagcatgat ctgataaatc ttcttattac acaagccaca      720

cctcatgttg ctcctgtgat gccattagat cgtttcatta cagattttta tacgactgta      780

aacaactatt ggattctaaa tgctcgacac ataaatttaa ccacactttc tgtagctgga      840

ggattccggg attaccaagt tcgttcagga ttgacttttc taccaaaatt aagccatcat      900

accagtgcct tatctgttgt gagttcagca gtgcctaaga cctgggtctc aacagaccac      960

ctctccattg tgtggtgtaa acaattgcag ttgactacag ttcgagcatt ctttgatctt     1020

attgatgctg atactaaaca aataactcaa aattccaaga agaaactgtc agttttgtat     1080

caccacttta taagacaccc atcaaaacat tttgaggaaa atccagctat aatttctgac     1140

ttaacaggga catctatgtg ggttctagta aaagtgtcca aatggaccta tgtagcttac     1200

aacgaatctg agaagatata ttttacattt cctcttgaaa atcatagaaa aatctacact     1260

catgtctatt gtcagagcac tatgctggat acaaatagtt ggatttttgc ttgcataaac     1320

agcacttcta tgtgcctgca aggggttgat ttatcatgga aagctgaact gctgccaaca     1380

attaagtatc tgacattaag acttcaagac tatccatctt tgtctcatct tgttgtttat     1440

gtaccatctg ttcgtggaag taagtttgtt gtagattgtg aattctttaa aaaagagaaa     1500

agatacatac agcttcctgt aactcatctt ttttcctttg gattgtcttc aaggaaagtg     1560

gtgttaaata caaatggcct atactacaat ctagagcttc tgaactttgg acagatatac     1620

caagctttta aaatcaacgt ggtaagcaag tgctcagcag tcaaagaaga aataaccagt     1680

atctatagac ttcatattcc ttggtcttat gaagattcac taaccattgc acaggctcca     1740

tcttccacag aaatttctct gaaactccat attgctcaac cagaaaacaa tacccatgtg     1800

gcattattta aaatgtacac gtcatcagac tgtcggtacg aggtgacagt taagacttcc     1860

ttttcacaaa tacttggaca ggtagttaga tttcatggtg gagctcttcc tgcttatgtc     1920

gtatctaata tccttcttgc ttatagagga cagttatatt ctcttttctc aacaggttgt     1980

tgcttagaat atgctaccat gttggataaa gaagccaaac catacaaagt tgatcctttt     2040

gtaattatca ttaagtttct gttggggtat aaatggttta aagaattgtg ggatgtatta     2100

ttgttaccag aattagatgc cgtcatttta acttgtcaga gtatgtgttt ccccctgata     2160

tccttgattc tctttctgtt tggaacgtgt actgcctact ggagtggcct actgtcttct     2220

gcatctgtga gacttctttc ttcattgtgg ctagctttga aaagaccctc tgaacttcct     2280

aaagatatca agatgatatc accagacttg ccctttttga caattgtctt gatcatagtt     2340

agttggacaa cttgtggagc actagccata cttctttctt atctttacta tgtgtttaag     2400

gttgttcatc tgcaagccag cttaacaact tttaagaata gccagcctgt gaatcccaaa     2460

cactctagaa gaagtgaaaa gaaatccaat catcataaag actcctcaat acaccatctt     2520

cgtttatctg ccaacgatgc tgaagatagc cttcgcatgc acagtactgt gattaactta     2580

ctaacatgga ttgtattact cagcatgcct tctctaattt attggctaaa gaatcttagg     2640

tattatttta aacttaatcc tgatccatgt aaacctttgg catttatcct tattccgact     2700

atggcaattc ttggaaatac ttacactgtt tcaataaaat caagtaaatt gttgaagact     2760

acttcacaat ttccacttcc tctggctgtt ggtgtgattg cttttgggtc agcacattta     2820

tataggcttc catgctttgt cttcattcct cttttactcc atgcattatg caactttatg     2880

taagattgga cttaaggaat gatgaagata atttatgtgt ttagggccag tgataagagg     2940

gaacacacag atccatcagt atggacagca agatcctttg gagaagacaa gtctattttt     3000

acaatattga aaataggaaa ttagttttgt aatgtttgag ggaagtagtt gaagcatggt     3060

tttgttttgt ggtgtggaat ccatgtagta atcatttttg aaaaattcat gaagggatat     3120

atggtgatca ctatcattga ggactcctgt gcatataaaa tagtctgttt tatcaactgt     3180

acgagaagtc tgatatgaga gatttagtag atgcagcatt atttgcagtc tcactgcaag     3240

cattctgctc atttcatcaa actttttttc acaaaagtag gttattttga atttgctata     3300

gtttacctat taagaaataa gtctttaaat aactgatgaa atttatagct gtttggtttc     3360

tcaaaggtta aatagccaca gaaagccttt ggttagtttt tggcagccac catgaacaaa     3420

gtggatcttg tcttcttaca tctatgaaaa tagagctttg aatggtaagg agatatgttt     3480

tcttggtaac caatgcaaga ttgatgggtg gaaacatgat tcaaacttac acaatttttc     3540

ttgctatttt tcaaatatga atcttactat atattctcgg tgaacatcag gagactatta     3600

aagaggtctg ctgttaaatg taaagaaaaa atgctcgtag ctatttgctt cctggtattg     3660

gagcagttca gttgtttagt ttataccatt ggattcaatt cattgcacca tggttgccaa     3720

aagtgcctga ggtcataatg gattgttaaa ataactaaat tccagtggtt ggaaactcta     3780

ggtttgtacc attttttctg ctgtgggaaa aaacaacaac aacaacatga tcaaggtaac     3840

atcacatttg atgtataata ttatactatt aatggaatat cagtagacaa ctgttaaccc     3900

attagtagca tgagtataaa cagtacacct gaataaattg gagacattag ccactaggtt     3960

taacagtgga atcttgattt gcctaggtga cttctgggat tactgtttga caaataagag     4020

taacatttta tttcatttca gaatttacgt cacttttagc tacaagagta ggaagaaggt     4080

aatcggcaag gcagaagagt atactctttg ccttaggata gcgtaaactc aggctgagac     4140

atacccggct tatagagttc ttctagatgt gtagactgta aatgcccaaa tcctctcaac     4200

taaagtttta gtgattccac aaagcctctc atgtaaattt ccagtgattc caccattgca     4260

cttgtgaata tgtatccttg ttagtaccca gggatgtcct cgagcaccag ttttatttta     4320

tctgccattg catctggatt ccattacagc ctctcagctg ttactgcctg tggacagtta     4380

cttctgctta ctgcctgtag agagttacct aacttctctt ctcagttctt cctcaggtcc     4440

tggctatttt ggcctcagtt gaagggagtc ttgctctcat ctctgagggt tttaagtttg     4500

tttgatccca ttgttgtctt ttctagcttt gagcatgttt ttcagtattc atattttaac     4560

ttactgagaa cattaaaggg aaatgataaa ctcgtggtgg ggatatggca gacaggtgct     4620

tgtttgtttg agagaagtag cagaagagat aaaatacaaa gtgctatatg tttcagctgg     4680

agaggaaaga gagagaattt attagattat atacttgtcc catggcatac cacgtatatg     4740

tttaaatagg gacacatctc cctatgttta actatactta taaacaactt tgatacacat     4800

tgcgtctttt attctgtcac ctgatatttt agtgtatctc aagttacaga ttacatgtgt     4860

ccttaaacta tttctgaatt tggacttagt tccatataca gaaagaactt tagaaaattc     4920

attaatttgg atcttctatt gatagccata aatattatgt ttatgtattc taaaacctct     4980

ttgtttagtt agtactgttc atgaatgtaa caagcttcaa tttctcattt gtgagtagta     5040

catttgcttt ttgtttgttt gtttgtttgt ttttgagatg gagtctcacg ctgtcaccag     5100

gctggagtgc agtggcgcga tttcagctca ctgcaacctc cacctcccag gtgcaagtga     5160

tgcccctgcc tcagcctccc gagtagctgg gactacagac acccgccacc acacctggct     5220

aatttttgta tttttagtag agacggggtt tcaccatgtt ggctaggctg gtctcaaact     5280

cttgacctcg tgatttgccc gcctctgcct ccccaaagtg ctgggattac aggcgtgagc     5340

caccacgccc agccgtacat ttacttttta aagcagcaga ctaggtacac taattctcac     5400

tcaaatattt tcatgggaat gtagttatca ccaagtccta aagtattatt tatgccaaaa     5460

aaaatttcat tttaaggact acaaaaatga ttctaattaa acattttata atcaatagta     5520

ggttgggtct ttagccatta tatgtgtata tatacagaca catatgtata cacttacatt     5580

ttgacagggt cttcattgag tcttgatgca ctttaaaccc agctggctac cagagatgcg     5640

aaggtgggct ctttgaagat tagcaaaatg gacgtttctg tcacttgaga aaaggaaagt     5700

tctttgcctt taaattacac agttttcatc atgcccacaa tctatattat tggctggtta     5760

aacagcactg ccctattagc aatgttaaca aaaatgaaat tatttattgg cggttataga     5820

ttatctaatt caggaaattt ctgagctcaa cttttacagc aactgttatg ccttctaatt     5880

tagcaattga gttatgagta agttttgtgc ttaactccta gaccctattg ttgataacca     5940

gatcaaatat agtctgtaca gaggaaaaca ctgggaacat ttagtatttc taaagcctcc     6000

tttggagtta ctactgattg taatttggaa ctgataatag gtagagattg ctaacactgt     6060

tttttttcct ggatcttttt tatgccagaa attaaacagg ttctgctaac tctttttttt     6120

ctcttggtta tcaccagaat gaaaatattt aaagtgatga ctctagaaaa gccatctgtg     6180

cctggttaac attgagtttg agtctcttca atatatattg atcatgtatt gattaatctt     6240

tattttttca tattttggct agacaaattc agatctatat aatggaatac cccttcttga     6300

gtgaactata ctactaatct acatgattat atagtaagga aaaaagaaga aataactgta     6360

ataggcatag tgtttgttgt tggttgtctt gtcattcatg tgatactact catttccaaa     6420

attcacacaa acttacatga ggtggattat ttgttttgtt cattatttag ttcctatatg     6480

ttttttcttt agaaacagag tctcattctg tcacccaggc tggagtccaa tggggcggtc     6540

atagttcact gcagccttga actctttggc tcatgtgatc ctcccatctc agcctcccac     6600

agcaggtgag actacaggta catgccactg tgcctgactt tttaattttt ttgtagagac     6660

gaggtttcag tttgttgccc aagctgatct tgaactcctg gtttcaagcg atcctcccac     6720

ctcggcctcc caaagtagtg ggatttcagg catgaccacc tggcctagtt cctatacttt     6780

tcttaattct tcagacttct cacatttagt atagtgcatt catttcatct tgctgtttat     6840

tagcaccctt tgtggccaag ggaaataaaa ggtggtaaaa ttcagttttc agtttagttc     6900

ttgaaagctc tgggaaatgg aggaaacaca aaactatgaa ttaaactagg gctgttgatt     6960

tctgaacccc cagataaatc agttgaccca cattttcatt ttaggtgtta ggtccaaatt     7020

agcataatgt cttgcattat tattaggttc agtgtgaaac tttacagtgc tgcatttgaa     7080

gtttagtaac tggttattat taatcatttg ggaaaaatga aaatgtgttg ggactttcta     7140

tgactaggca tttgttgatt atttttcatg attgcttttt gttttctcat tgtgtaggat     7200

ttgtgaactt gtatattaca ggaaacaaga tactttgtaa aatttactgg ggaaaatcca     7260

tttggagtgc atgacatttg ccaggataag aaagcagtaa tatgtttgta ttataaaatt     7320

acaccctgcc agaaaacttt ctttcctagt aaggtaaatg tagaagggac ttttacagca     7380

tagtaagttg attaggagcc aaaattttat tccagttttt ttttgaacta agaatgtttt     7440

aaattctgta atgaactttt atgtttaccc attactcatg cattctttca caatatgttt     7500

aatagcctga ggaaatagga aagctgtgaa gctactacca ttctttactt ttaataagaa     7560

taataggaaa gaaaagtcag gtcagtaatc caaatccaaa tatgtatact gcaaatgctc     7620

aagaagtcac attttttgat aaattgtatt gagtacagaa gaacttatat gaatttatta     7680

tctgttaata acttagtttt gacaacagaa taacatttgg aaattgtgag aataatcaag     7740

ctgtttttcc attaacagtg taaattcata acatgtcctt caaaaggtga tattctaagc     7800

tgtcttaatt gtctacggtt gataactttt aaataaagta caggactttc tgaaagtgtt     7860

tggcatgtta tgctgccaaa aacaatctgt gttttgaaat accaattaat cagttaattt     7920

ctgaagactt tgtataggac ttgatatatg agtcagaatc tgtctgtact cattctgtac     7980

attgtaactt tgaacactta tgaaaaactg tatctgttgg tgtgttttga ttagttagtg     8040

tagatttgtt tgcgtatttg aattccgatt ttagtttagg aagactaaaa gtagccattt     8100

ttgtaaagtt catatgctat tttttaatgt catttttgtt tttaatattt atacaatagt     8160

gatgttacta gtaaaaaatg tttatagata acacgtagag ctattaactg ttcaaaagcc     8220

tacatgatag gcatattttg tatttcgtgt tgcactcgtt ctgtttcata ttggactttt     8280

tacatccctt ttttagcaaa aaaaagagac acatttgaat tctctttagc ataaagctgt     8340

gcattggaaa ctatgtgact gtatccatac ggttagcaaa atactctttg ccaccaaagg     8400

taaatgaaac tgtaaaatac ctctggatat ttgtgccaat gaacttttct tagcatatta     8460

ggattaaagc aaaaataatc ttttcagtat gtttcatcta ggacttacaa taaatgttta     8520

aaccatgaaa acttatattt cataccctaa tttttctttg aaaatattca agatttgtag     8580

cctagtgtgt tctattttgt gtgattgctt gaatgttttc tgattttatt gggtaaaagt     8640

ttgcctagta atgatctttc agcaattcat tgaaataatt atttgaagta atcttgcttc     8700

agatttaatt tgtgatgtac attgttgtac aagccatttt agtacaggtg tctcatttat     8760

gtagttgaaa ggtgactgtg gaatttcttt tgttttttat gtatttccat tcagtctctt     8820

tatatagtca catgtttcac aggggaactt gtccactgga acctaacata gtacaacctt     8880

ttaatatgcg tatcttaaag gaaaatatta taaaacaaga tattaatact aaagtgttaa     8940

cattaatatg ttgttctcat ggaagaaaag tagaaaatgt gataggctta gaaattattt     9000

tttatcagca ttaagtgctt caatttctcc ccataaagat tctaaggaaa tttcagttcc     9060

tcatattata gttttcccca taatttaata ttactaagta tttctctgcc cagtaatgtt     9120

gatgcagttt gcataaatag ccttggaagt aaggaggcag gacagaaagc caaatatcga     9180

aatctctggc cttgatttag tgacagttta ttctaatggg gaccataggt gttattagta     9240

aaaagatagt gtacaaggcc taagttcagt ttacattgtt ctttgaaatg agttcatctt     9300

ttgtgttgaa taattgtatt ctaagtagga gatgcctgta tttaacataa tcatgctttc     9360

tatataatca aatatgtatt tgttggaata ctggtagaaa taaccttccc ttcctccact     9420

gtgcagtgga aaaaaaactc ccgatttata ctgtatataa attaggaaat tatgttacat     9480

atttacattt ttaaaaatat aaaaatgaca tattattttg aagtgattgt attatagttt     9540

ctgaagctta tgactggcta taaatataac aacataccca tgagaaacca gaccaaaatt     9600

gaatatatat catcactgtg accttgaact tatagtcatt tgggataaaa cagagtgtgc     9660

cttgaaatga taaagagtgc cctgcaattt tataactgta cattttatta tgggtggtcc     9720

tctcaaattg gccccaaatc cttgtcttcg aggttggtga aataaaagtt taaaataaaa     9780

gttgactggt atttccttta gtatttccag aactattgct gtagaggcct cccttaattt     9840

tcagagttct cattttgaat taaagtagac ttacgctaca tagatgtaga aaattaggtt     9900

tggcttaggt ttctgaaaaa atattctagg agaaggtggt agcattgttc tgaacttacc     9960

acacttggaa aaactaatct tcaaatgtaa ttttttgtct tattaatgag taatctgtca    10020

aagacatgaa ttctttgact tgtgctcatt ctttctgaac ttattgaggc ttatatatat    10080

caaataaggt taatttacac aataattatt tttaataatt aataaactca ttcatgtagt    10140

atattttaaa acattatttc ctctcatttt tccttctctt ttttcttcct atatattttt    10200

aaggcttcaa gagaaaacgg gcttcagttt ttaaaaaaat gtagacttgc atttttactg    10260

tgcttattta aaataatgga tataatttat attaaggtcc aaattatttt attcacagga    10320

taatcatggt ctctgataaa agatgcccac atttctgtgt actcacagtt gttgtatatt    10380

tttcaatttc aattttgaaa gtaaactcaa cacattgttt tcccatttta cctccactac    10440

ctactcgcca gacaaaaata tagatttctc taaaaacaca tacaaagaaa atgtctttcc    10500

ttaaaacatg atcttattga catgaaggta gtttgagcaa gggtatgtaa taaaataaat    10560

ggctctcaac ctgcatcaat ttttatacta tagttaaaaa atttatagag gacaacctat    10620

gtgttatgct gagatagact cagtaatcat ttgtttgcaa attgattatt tttttctcat    10680

ccatccagaa agtacagtgc ataacaacaa cacttaacaa gtgcagagga acctgtcctg    10740

tagtatataa taaaaaatga ttgtcacctt gctgatcttt ccatttaaac atgcatgatc    10800

tccagtactt tgtacaatgt atagtatatt aaatacattt atgtgtaatt ttgtgtgtat    10860

ttttatatgg tataattaaa attattacat ttatgtgatt gtaattcaca aaaagtacta    10920

cttactatat tctgtagagt gtgttgtgaa tgtttttacc tgtgtttgag cattatggtg    10980

taggtttaat agatgaatat ttgccttcag tctctgctca ggtattaatg tgtagtaatt    11040

tttggtgctt tctttttaat ctgtgataat ctggtgttct gaatgttcaa aaataaattt    11100

ggttgaatac gca                                                       11113


<210>  945
<211>  2653
<212>  DNA
<213>  homo sapiens

<400>  945
agtaattaga gctaagcggc aattacagga cgtatgattt gttcagaagc actgcctgcc       60

ggctgtttcc tagcaccaca tttcacggga gcaccaggtt gagatgatgg aattatttac      120

ttttaaatgt aacatctcgt acagtgctca aatgcagacg tgaacgtgga ctgtaacctt      180

aaaaacaaag gcagtacatg ccacactact acccttcctg ctcttgtgcg cacacctacc      240

ctgatgatgc agccttcact ggatatcaaa ccatttatgt cttttccagt ggacagtagt      300

tctgctgttg ggctctttcc aaattttaac acaatggatc ctgtgcaaaa agcggttatt      360

aaccatacat ttggagtatc cattccccca aagaagaaac aagttatttc ttgtaatgtc      420

tgtcagcttc gctttaactc agatagccag gccgaggccc actacaaagg aagtaaacat      480

gccaagaagg tcaaagcact agacgcaacg aaaaataaac ccaaaatggt tccttccaag      540

gacagcgcaa aggctaatcc cagctgctcc atcactccaa tcacaggcaa caactctgac      600

aaatcagaag ataaagggaa gttaaaagcc agcagttcca gtcagccatc aagctctgaa      660

agtggctcat ttctcctcaa atctggcaca acacccctgc cacctggagc agccacttct      720

ccctccaaga gcacaaatgg agctcccggt actgttgttg aatcagaaga agaaaaagcc      780

aaaaaattac tttattgttc actatgcaaa gtggctgtga actccctgtc acagctagag      840

gcacacaaca caggatctaa acacaagacc atggttgaag ctcgtaatgg ggctggtcca      900

attaaatcct atcctagacc tggatcaaga ttaaagatgc agaatggcag taaggggtca      960

ggactacaga acaagacatt tcattgtgaa atctgtgatg ttcatgttaa ttcagaaatt     1020

caactcaaac agcacatttc tagccgaagg cataaagatc gagttgcagg gaaaccactg     1080

aagccaaaat acagccctta caacaaactc cagcggagcc cgagtattct agcagcaaaa     1140

cttgcattcc agaaagatat gatgaagcct ttggccccag ccttcctgtc ctcacctctc     1200

gcagcggcgg cagccgtgtc ctcagcgctg tcactcccac cccggccctc tgcctcgctc     1260

ttccaggctc cagccattcc tccagctctt ctgaggcctg ggcatgggcc catccgcgcc     1320

actcctgcct ccatcctctt tgctccgtac taacgtctgc aaaccccaag acgtttgagg     1380

ccagtaggaa gttgagaaag aaagccacaa ggattcagca atttaagcag tttgtgttgc     1440

agtacccccc attcacccac aaaatgcagc ccaccaccca gtcccccaat tccagagaga     1500

aacacatcac tagattgacg agggctttta gagactgctc ctataattga ggaatcagca     1560

gcataggctt tatctcccta cttcctcccc caccctaccg cgttcaattt gtgtatctca     1620

gatatttgat ttcttgagca tgtattggtc agaaagaaaa agaaagaaaa ccattctcta     1680

tttttccatg ggtatgatct ggcttaaaac aatatggaat attttcctga cagacttgaa     1740

aactaggatc ttcctcagat gtctgtaaat aactctggta tccaactggg tgtattctag     1800

tgtggaacaa aaaacagtga acacaagtgc ttacttgtgg atactatctt accaacggat     1860

cacaaagttc tctttttggt gtactgttgt tgacagggat tgtgtactgt ttcgacccaa     1920

gtactgctgt atcctgtgta gtactagatc tgtatctctt gtctgaatta aacattttta     1980

gttgctgtgt aaatgttagg aagcaaagta gctttgaatt ttctctgtaa gagaataaaa     2040

gataaaataa tgtattttct ttatttcaca ttttatttgg agatatttaa atgaaataga     2100

aagccatata acatagctat aattactacc tgtttgctat ttttgtttaa cttattttgt     2160

agcttcctca ctggtttgtg ttgctaagca aacgtataca aacagaaaaa gagcttccta     2220

aattgcacat ttttgcacct cttgtgcatt ctgcaagaag acaatgaatc catgtatttc     2280

tatataagta tcttcttcat ttttaacctg ttttcatttg taatgatgct acataatttt     2340

gtggctccct aatgcaataa tgtacagaag ataaaaaaat ttataattga acaatttgtc     2400

tttctgttcg ctgaatatat tgcaggtcat gctcccatgc ccccctttct aagccgatat     2460

caacaagact ggaatgtttg tgatatcagg ggcaagagtt atcatagaac aacaaaatag     2520

agtggactct tttagagcat ctatatctgc aacctgtaaa tggtaaaatg tctgtgtatt     2580

tttttaaatg taccttttca ataaaagtac aaaaaataaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaa                                                        2653


<210>  946
<211>  4772
<212>  DNA
<213>  homo sapiens

<400>  946
aagggcgctc cgcgagcccg tctctcctcg aatgaaagga aacaacctcc ggcgacagag       60

ccccgctctc aggcactgct ggagaaccga gaccgacttc tttctcttta ccctcattgg      120

cgcttctctc ctgcagtccg cctctgggcc ctgccgcatt tcttgagact taaagtggca      180

ttctaaaggc aatttaaaaa tcatgtcaag ctcagttgaa cagaaaaaag ggcctacaag      240

acagcgcaaa tgtggctttt gtaagtcaaa tagagacaag gaatgtggac agttactaat      300

atctgaaaac cagaaggtgg cagcgcacca taagtgcatg ctcttttcat ctgctttggt      360

atcatcacac tctgataatg aaagtcttgg tggattttct attgaagatg tccaaaagga      420

aattaaaaga ggcacgaagc tgatgtgttc tttgtgccat tgtcctggag caacaattgg      480

ttgtgatgtg aaaacatgtc acaggacata ccactaccac tgtgcattgc atgataaagc      540

tcaaatacga gagaaacctt cacaaggaat ttacatggtc tattgccgaa aacacaagaa      600

aactgcacat aactccgaag ctgatttaga agaaagtttt aatgaacatg aactggagcc      660

ctcatcacct aaaagtaaaa agaaaagtcg caaaggaagg ccaagaaaaa ctaattttaa      720

agggctgtca gaagatacca ggtccacatc ctcccatgga acagatgaaa tggaaagtag      780

ttcctataga gataggtctc cacacagaag cagccctagt gacaccaggc ctaaatgtgg      840

attttgccat gtaggggagg aagaaaatga agcacgagga aaactgcata tatttaatgc      900

caagaaggca gctgcccatt ataagtgcat gttgttttct tctggcacag tccagctcac      960

aacaacatca agagcagaat ttggagactt tgatattaaa actgtacttc aggagattaa     1020

acgaggaaaa agaatgaaat gtacactttg cagtcagcct ggtgctacta ttggatgtga     1080

aataaaagcc tgtgttaaga cttaccatta ccactgtgga gtacaagaca aagctaaata     1140

cattgaaaat atgtcacgag gaatttacaa actatactgt aaaaatcata gtggaaatga     1200

tgagagagat gaagaagatg aggaacgaga gagtaaaagc cgaggaaaag tagaaattga     1260

tcagcaacaa ctaactcagc agcaacttaa tggaaactag gtatgaaagt taattatatg     1320

ggatctgttg tcaggataca atacacactg atatatacat gttgaagtaa tggtatgcag     1380

taagattttt tttaatccta ttatgtttag ttaagagcat gttactaaaa tgctgaggat     1440

tttgtaggct tgcatagtag ttgtttttta actagctgat tttgtaacca taaaaacaag     1500

ctatctgctt tatcaataag tgtagttgta atgtcaaatc aataagatat tcacactcct     1560

caataacatt atattgattg tgttcccctc aagcatcata ttttacattt ttttatcatc     1620

ttttaaacag gttcatggga cagagttaga aaactgggaa tgaataagac atccataact     1680

actattcttt tttcactgtt ttctaaaatc aaaaagggtt tgtaactttt tactgcccaa     1740

ctcttagatc cttcattgaa ctgcctaaaa atgtcttgtt tgttttatga gccctcacta     1800

gaaggctgag tttgacatgt tgatattacg tagctatagt ttgcagtttc tgggaagcaa     1860

ttgaaacact attaaccctg tgtatagtgt caacagttaa agcagacgaa acgaagtaag     1920

ctatatttct ggactgaaca aagctctgct gtttagagca tttaagtttg tttagtggat     1980

ccatactcaa aggaaagcat aagcaaattt tcctttacaa tgcaaacatg ccactggtgg     2040

cagcacatgg taatttgtgg attttttttt catactcaag taatggaggc tagaaatgaa     2100

gagaaccttc tttttctctt gactttgaca gcacatgcta aaaatctctt ccaagaagta     2160

tgctaaagct tttcatttgg ttcctgttaa agttgttctc actgaccagc atggactcag     2220

gcaactggta atgataagct atgagctcca gtgcttttgc caaaattctc ttgacagcac     2280

acctcctctc tttccatgtt atacaaagga cttctggcaa aatgattgag tccttcaagt     2340

ttaaactaac atttggcaac agcaaattaa acgtttttaa gatgtaaaga aagggttacc     2400

gcttgctaag gacttcagac accatgtccg aaacctgttc ctctcaagtg ccctgttgtg     2460

tggaacactt cacatattgg cgcacagtac gtaaggaggt ctcatgtgct gtaggagtaa     2520

aaaagtcttt gcataaaaca gtatttattt ttacttttgt gaccactatt ttagaaactt     2580

tatttaatat tttaatgttt tcagtcattg ctttggttat ctataaaata ggcttttgtg     2640

ccctactttt cttcttgtag ggcttggtgg tgttttatcg attgtcagaa ttgtttttga     2700

aagcctaaga acccagcttt ttagaaagga ttttcacact ggcatttcta ggtagtgata     2760

ttttcttcca cttacctgct gaagcacatt tatgcatttc tttatggcaa aaccaaataa     2820

ctttagttgt ggtctgcctg atactaccat agcacctcag taccaagggg agggattttg     2880

actagttgaa ttattaagcc accacaataa agcagatttt taaataagaa ataataatgt     2940

taacttgact gtacattgag atattctgca gctgatagag cagcatttta aaaatgtaac     3000

aggtggaaaa ttacactgtg cttaatgact gatttttttt taaactgcga gtcccttaag     3060

atcacgtttg tcaagtgtgt attcacacat ttacttaaat caagggactc aatgcttgct     3120

tttattttaa ccatctttta ctatttttag aaggaaacta gctttagtag tgggttgccc     3180

tgtatgtttt ctctttttgc tcttaatatg ccattgggtt tttgtgtgta tgtgattttc     3240

aaaattcatg acttgaagtg caaggacaga tctagatgtt tgtttaccaa gctatgtgac     3300

ttctcccaaa ggatctgtac tttctttcct tacaacagct tgaaaatcat tattttaaaa     3360

tccttaaatc actgtgtcta gatcattttt tacattgtgt gccatagact tacccatggg     3420

acaacagagc tccttcattt ttggacaact actgtaatca tttttttttt aggaaaaatg     3480

gaaggtgccg ggggtaatca tggccagtca ataattatat aaaggagttc aaatactata     3540

gctgtcagtt gatgaatttg ttatgtagta aaatgtatga ctttgtatgg gtttcttcag     3600

ccctttttct gccactagca accagaatag cactttacct tttggttggc tagataagtg     3660

gctgactacc tgtttttctc actgtggtgt gattggctaa acaatctcgc attaaaaatt     3720

caaatgtaaa ttgaattcac atgaaaaatc atgtttggtt gtaaacctcc aatgttttga     3780

ttctctaatc atgttttcgt cacatgctga gtaaaagtgc cttacaatgt aaaaattgta     3840

cagtacttat gttcccaagt agcatcatca tcttctgggt agtaattaca ttgtggtatt     3900

aatatttaga aaaatggacc tcagcagtgt atttactgta catctcttaa gtccttaact     3960

gtagttttaa taagcatgac attatttgat aagtatataa catttacatc atttcaaaaa     4020

atactgccgt tactgtcttt tatgcatatt ttagcctgaa attttgaagc gtcttttttc     4080

tttctttttt ctttttttgt tttgtttttt gttattgata ttaaacagtg taatctttgc     4140

aagcgtatat tgaagattat tctggagcat ttattgcctt accagaaatg ttagtaggaa     4200

atgttcttta gagtagaaag atagacttga gtttctatac ttttaagaag agctctttgt     4260

tcctggggga ggggggcagg gggtgaattt tactttcatc tcaagttatt aaaaacccac     4320

aactgaagta aattttattt caagaatcag cagttttaga atttcagata gtacttgctc     4380

agaagtacat gctactcaag atattaagag ataacaagat ctgtagatct gctattgaat     4440

cagaatctgt gtacttgaac aaatgtgtga atctcaaata tctcaaagca aaagaaaaag     4500

tgttctagag tgttgttgct tttttaaaaa aagcgctgaa gttagaccaa ggtatacagt     4560

tttgttctaa cagacattta ggttaattgt aaagataagg aatgcattat gggtcaaaaa     4620

tcaaacattc ctctcatgtt atgtatattt tgttcctgtt atattggctt tattttcaaa     4680

attgtagttt gtagtattag tttcctttta ttggtattct tgcatatact attcattcaa     4740

taaatgactt atgactttca taaaaaaaaa aa                                   4772


<210>  947
<211>  1236
<212>  DNA
<213>  homo sapiens

<400>  947
aagggcgctc cgcgagcccg tctctcctcg aatgaaagga aacaacctcc ggcgacagag       60

ccccgctctc aggcactgct ggagaaccga gaccgacttc tttctcttta ccctcattgg      120

cgcttctctc ctgcagtccg cctctgggcc ctgccgcatt tcttgagact taaagtggca      180

ttctaaaggc aatttaaaaa tcatgtcaag ctcagttgaa cagaaaaaag ggcctacaag      240

acagcgcaaa tgtggctttt gtaagtcaaa tagagacaag gaatgtggac agttactaat      300

atctgaaaac cagaaggtgg cagcgcacca taagtgcatg ctcttttcat ctgctttggt      360

atcatcacac tctgataatg aaagtcttgg tggattttct attgaagatg tccaaaagga      420

aattaaaaga ggcacgaagc tgatgtgttc tttgtgccat tgtcctggag caacaattgg      480

ttgtgatgtg aaaacatgtc acaggacata ccactaccac tgtgcattgc atgataaagc      540

tcaaatacga gagaaacctt cacaaggaat ttacatggtc tattgccgaa aacacaagaa      600

aactgcacat aactccgaag cagctgattt agaagaaagt tttaatgaac atgaactgga      660

gccctcatca cctaaaagta aaaagaaaag tcgcaaagga aggccaagaa aaactaattt      720

taaagggctg tcagaagata ccaggtccac atcctcccat ggaacagatg aaatggaaag      780

tagttcctat agagataggt ctccacacag aagcagccct agtgacacca ggcctaaatg      840

tggattttgc catgtagggg aggaagaaaa tgaagcacga ggaaaactgc atatatttaa      900

tgccaagaag gcagctgccc attataagtg catgttgttt tcttctggca cagtccagct      960

cacaacaaca tcaagagcag aatttggaga ctttgatatt aaaactgtac ttcaggagat     1020

taaacgagga aaaagaatgg tctgtagttt ttatatttgt tatgcaacat tacacttgat     1080

ttgctgcttt aaatttagag tacatcccaa atttatccag tcatcagaaa atttaaagta     1140

gttcgtatgt taaagcaaag tatatatttg acttatttgt aatataataa aggatgctga     1200

tgttactgaa aaaaaaaaaa aaaaaaaaaa aaaaaa                               1236


<210>  948
<211>  3353
<212>  DNA
<213>  homo sapiens

<400>  948
gcggcggcgg cgcgggacgc gtcacatccc cttgaccctc caatcacctc gggctcccat       60

ttgattggaa ggcggcaaag gctttaatct cccccttggt gcagctgctt ttgaagtgag      120

tttcctcgcc agagccccgg ctggacacgc agcggctcgc atcgcagagc gcagcgccgg      180

cgcggggccg cgagaacgca gcgcagggga gcagcccgag gcggacaccg cgagccgccc      240

ggcactcccg cagtccagcc ggctcctcta gcccggccac ggctccgctg cgggccaccc      300

aggattactc gcgtctggct ccaggcgccg agaaggcgcg ctgggcgccc gtggccgccg      360

cgccagctcc tcctcctccc gctgctcctg ctcccggggc gagcgcgcag ccccgagccc      420

gccccgcgcc tcccggagcc ctcccccccg ctgctcccat gcgcgcgggt gggtcatgag      480

cacagcgccc tcgctttctg ccctaagaag cagtaagcac agcggcggcg gcggcggcgg      540

aggcggaggc ggcggtgcag accctgcctg gaccagcgcg ctctctggaa atagctccgg      600

ccccggccca ggctcgtccc cggccggcag caccaagcct tttgtgcacg ccgtgccccc      660

ctctgacccc ctgcgccagg ccaaccgcct gccaatcaag gtgctgaaga tgctgacggc      720

acgaactggc cacattttgc accccgagta cctgcagccc ctgccttcca cgccggtcag      780

ccccatcgag ctcgatgcca agaagagccc gctggcgctg ttggcgcaaa catgttcgca      840

gatcgggaag cccgacccct cgccctcctc caaactctcc tcggttgcct ccaacggggg      900

cggcgcgggc ggtgccggcg gcggtgctgc gggcgacaag gacaccaaat cgggccccct      960

gaagctgagc gacatcggcg tggaggacaa gtcgagtttc aagccgtact ccaaacccgg     1020

ctcggataag aaggagccgg gaggcggcgg tggaggcggt ggcggtggcg ggggcggcgg     1080

cgggggtgtt tcgtcggaga agtcgggatt ccgggtaccg agcgccacct gccagccatt     1140

cacgcccagg acaggcagcc cgagctccag cgcctcggcc tgctcgccgg gaggtatgct     1200

gtcctcggcc gggggtgccc cggagggcaa ggacgacaag aaagacaccg acgtgggcgg     1260

cggtggcaag ggcaccgggg gcgcctcggc cgaaggggga cccacggggc tggcacacgg     1320

ccggattagc tgcggcggcg ggattaatgt ggatgtgaac cagcatccgg atgggggccc     1380

gggaggcaag gctctgggct cggactgcgg cggttcatcg ggctccagct ccggctccgg     1440

ccccagcgcg cccacctcct cctcagtgtt gggctctggg ctggtggctc ccgtgtcacc     1500

ctacaagccg ggccagacag tgttccctct gcctcccgcg ggtatgacct acccaggcag     1560

cctggccggg gcctacgccg gctacccgcc ccagttcctg ccacacggcg tggcacttga     1620

ccccaccaag ccgggcagcc tggtgggggc gcagctggcg gcggccgcgg ccgggtctct     1680

gggctgcagt aagccggccg gctccagccc tttggccgga gcgtctccgc cgtccgtgat     1740

gacagccagt ttgtgccggg acccttactg cctcagctac cactgcgcta gccacctggc     1800

aggggcggcg gccgccagcg cttcttgcgc acatgatccg gctgctgcgg ctgcggcgct     1860

gaagtccgga tacccgctgg tgtaccccac gcacccgctg cacggtgtgc actcctcgct     1920

aacggccgcc gcggctgctg gcgccacacc gccctccctg gccggccacc ccctctaccc     1980

ctacggcttt atgctcccta acgacccact cccccacatc tgcaactggg tgtcggccaa     2040

cgggccgtgc gacaagcgct tcgccacgtc cgaagagctg ctgagccact tgcggaccca     2100

tacggcattt cccgggacag acaaactgct gtcgggctac cccagctcgt cgtctctggc     2160

cagcgctgcc gcggccgcca tggcttgcca catgcacatc cccacctcgg gcgcaccggg     2220

cagccctggg acgctggcgc tgcgcagccc ccaccacgcg ctgggactca gcagccgcta     2280

ccacccctac tccaagagcc cgcttcccac gcctggcgcc cccgtgccgg tgcccgccgc     2340

caccggaccg tactactccc cctacgccct ctacggacag agactgacca ccgcctcggc     2400

gctggggtat cagtgagggc ggccgggagg gcgagcgagg gagaggaggg agagggggag     2460

gggaggagtc cagggagagg cgggatcacg gcccaggctg ctgacacccg cgcgtgggga     2520

ggactcgggc cacgaaagga aagaaatgta taccgtatct atctacccga cagcagcgac     2580

cgagacccgg tgggacactc cccttctccc cactttcacc tccccaccca aactttataa     2640

aagttgaaaa aatatcattt gactttttat agaaaaaaaa aggaaaaaat aattgagaaa     2700

gtgttcatct gaggactgca tcggtggaca ctggtattta tttatgttag ctccaagcgg     2760

accggtggtt caaaagtgca ttatttagtt tgagctctgt aggtaaaaag gaggtgggaa     2820

aaattttaaa acttgagggt aaaaatgtgg aaaacaaacc ctcccatccc ttgtagatta     2880

taaataaaag caaaaccgcc acagaactag aggtcttctc tttaatgtta ctttaaaatt     2940

gctatgattg tattgtacgt tatttaatgt ctgattgaaa cacaaattta catgcatgtt     3000

tgttacaaaa aaaatgaaaa aaaaagtcac aatttgtcag ctctgatttc aaattgcaat     3060

tatttttaag gtgtatacca tcgaagagaa tgggtatttt tttgtatgta ttctggaaga     3120

aaacaacaaa aaaaaaaaga aaaagaaaaa attctattcc aaaacctcat ttgccttatt     3180

ttgttcttta aaaggaacac ttaactattt ttaattttta agtccacccg ctgagaaggg     3240

gacaaggttt acgtcatgta ctaaaataat agacaatgta tcgctttaaa gattaaaatt     3300

ccgtatattt gatgtattaa agggttttac ttcttaaaaa aaaaaaaaaa aaa            3353


<210>  949
<211>  4772
<212>  DNA
<213>  homo sapiens

<400>  949
aagggcgctc cgcgagcccg tctctcctcg aatgaaagga aacaacctcc ggcgacagag       60

ccccgctctc aggcactgct ggagaaccga gaccgacttc tttctcttta ccctcattgg      120

cgcttctctc ctgcagtccg cctctgggcc ctgccgcatt tcttgagact taaagtggca      180

ttctaaaggc aatttaaaaa tcatgtcaag ctcagttgaa cagaaaaaag ggcctacaag      240

acagcgcaaa tgtggctttt gtaagtcaaa tagagacaag gaatgtggac agttactaat      300

atctgaaaac cagaaggtgg cagcgcacca taagtgcatg ctcttttcat ctgctttggt      360

atcatcacac tctgataatg aaagtcttgg tggattttct attgaagatg tccaaaagga      420

aattaaaaga ggcacgaagc tgatgtgttc tttgtgccat tgtcctggag caacaattgg      480

ttgtgatgtg aaaacatgtc acaggacata ccactaccac tgtgcattgc atgataaagc      540

tcaaatacga gagaaacctt cacaaggaat ttacatggtc tattgccgaa aacacaagaa      600

aactgcacat aactccgaag ctgatttaga agaaagtttt aatgaacatg aactggagcc      660

ctcatcacct aaaagtaaaa agaaaagtcg caaaggaagg ccaagaaaaa ctaattttaa      720

agggctgtca gaagatacca ggtccacatc ctcccatgga acagatgaaa tggaaagtag      780

ttcctataga gataggtctc cacacagaag cagccctagt gacaccaggc ctaaatgtgg      840

attttgccat gtaggggagg aagaaaatga agcacgagga aaactgcata tatttaatgc      900

caagaaggca gctgcccatt ataagtgcat gttgttttct tctggcacag tccagctcac      960

aacaacatca agagcagaat ttggagactt tgatattaaa actgtacttc aggagattaa     1020

acgaggaaaa agaatgaaat gtacactttg cagtcagcct ggtgctacta ttggatgtga     1080

aataaaagcc tgtgttaaga cttaccatta ccactgtgga gtacaagaca aagctaaata     1140

cattgaaaat atgtcacgag gaatttacaa actatactgt aaaaatcata gtggaaatga     1200

tgagagagat gaagaagatg aggaacgaga gagtaaaagc cgaggaaaag tagaaattga     1260

tcagcaacaa ctaactcagc agcaacttaa tggaaactag gtatgaaagt taattatatg     1320

ggatctgttg tcaggataca atacacactg atatatacat gttgaagtaa tggtatgcag     1380

taagattttt tttaatccta ttatgtttag ttaagagcat gttactaaaa tgctgaggat     1440

tttgtaggct tgcatagtag ttgtttttta actagctgat tttgtaacca taaaaacaag     1500

ctatctgctt tatcaataag tgtagttgta atgtcaaatc aataagatat tcacactcct     1560

caataacatt atattgattg tgttcccctc aagcatcata ttttacattt ttttatcatc     1620

ttttaaacag gttcatggga cagagttaga aaactgggaa tgaataagac atccataact     1680

actattcttt tttcactgtt ttctaaaatc aaaaagggtt tgtaactttt tactgcccaa     1740

ctcttagatc cttcattgaa ctgcctaaaa atgtcttgtt tgttttatga gccctcacta     1800

gaaggctgag tttgacatgt tgatattacg tagctatagt ttgcagtttc tgggaagcaa     1860

ttgaaacact attaaccctg tgtatagtgt caacagttaa agcagacgaa acgaagtaag     1920

ctatatttct ggactgaaca aagctctgct gtttagagca tttaagtttg tttagtggat     1980

ccatactcaa aggaaagcat aagcaaattt tcctttacaa tgcaaacatg ccactggtgg     2040

cagcacatgg taatttgtgg attttttttt catactcaag taatggaggc tagaaatgaa     2100

gagaaccttc tttttctctt gactttgaca gcacatgcta aaaatctctt ccaagaagta     2160

tgctaaagct tttcatttgg ttcctgttaa agttgttctc actgaccagc atggactcag     2220

gcaactggta atgataagct atgagctcca gtgcttttgc caaaattctc ttgacagcac     2280

acctcctctc tttccatgtt atacaaagga cttctggcaa aatgattgag tccttcaagt     2340

ttaaactaac atttggcaac agcaaattaa acgtttttaa gatgtaaaga aagggttacc     2400

gcttgctaag gacttcagac accatgtccg aaacctgttc ctctcaagtg ccctgttgtg     2460

tggaacactt cacatattgg cgcacagtac gtaaggaggt ctcatgtgct gtaggagtaa     2520

aaaagtcttt gcataaaaca gtatttattt ttacttttgt gaccactatt ttagaaactt     2580

tatttaatat tttaatgttt tcagtcattg ctttggttat ctataaaata ggcttttgtg     2640

ccctactttt cttcttgtag ggcttggtgg tgttttatcg attgtcagaa ttgtttttga     2700

aagcctaaga acccagcttt ttagaaagga ttttcacact ggcatttcta ggtagtgata     2760

ttttcttcca cttacctgct gaagcacatt tatgcatttc tttatggcaa aaccaaataa     2820

ctttagttgt ggtctgcctg atactaccat agcacctcag taccaagggg agggattttg     2880

actagttgaa ttattaagcc accacaataa agcagatttt taaataagaa ataataatgt     2940

taacttgact gtacattgag atattctgca gctgatagag cagcatttta aaaatgtaac     3000

aggtggaaaa ttacactgtg cttaatgact gatttttttt taaactgcga gtcccttaag     3060

atcacgtttg tcaagtgtgt attcacacat ttacttaaat caagggactc aatgcttgct     3120

tttattttaa ccatctttta ctatttttag aaggaaacta gctttagtag tgggttgccc     3180

tgtatgtttt ctctttttgc tcttaatatg ccattgggtt tttgtgtgta tgtgattttc     3240

aaaattcatg acttgaagtg caaggacaga tctagatgtt tgtttaccaa gctatgtgac     3300

ttctcccaaa ggatctgtac tttctttcct tacaacagct tgaaaatcat tattttaaaa     3360

tccttaaatc actgtgtcta gatcattttt tacattgtgt gccatagact tacccatggg     3420

acaacagagc tccttcattt ttggacaact actgtaatca tttttttttt aggaaaaatg     3480

gaaggtgccg ggggtaatca tggccagtca ataattatat aaaggagttc aaatactata     3540

gctgtcagtt gatgaatttg ttatgtagta aaatgtatga ctttgtatgg gtttcttcag     3600

ccctttttct gccactagca accagaatag cactttacct tttggttggc tagataagtg     3660

gctgactacc tgtttttctc actgtggtgt gattggctaa acaatctcgc attaaaaatt     3720

caaatgtaaa ttgaattcac atgaaaaatc atgtttggtt gtaaacctcc aatgttttga     3780

ttctctaatc atgttttcgt cacatgctga gtaaaagtgc cttacaatgt aaaaattgta     3840

cagtacttat gttcccaagt agcatcatca tcttctgggt agtaattaca ttgtggtatt     3900

aatatttaga aaaatggacc tcagcagtgt atttactgta catctcttaa gtccttaact     3960

gtagttttaa taagcatgac attatttgat aagtatataa catttacatc atttcaaaaa     4020

atactgccgt tactgtcttt tatgcatatt ttagcctgaa attttgaagc gtcttttttc     4080

tttctttttt ctttttttgt tttgtttttt gttattgata ttaaacagtg taatctttgc     4140

aagcgtatat tgaagattat tctggagcat ttattgcctt accagaaatg ttagtaggaa     4200

atgttcttta gagtagaaag atagacttga gtttctatac ttttaagaag agctctttgt     4260

tcctggggga ggggggcagg gggtgaattt tactttcatc tcaagttatt aaaaacccac     4320

aactgaagta aattttattt caagaatcag cagttttaga atttcagata gtacttgctc     4380

agaagtacat gctactcaag atattaagag ataacaagat ctgtagatct gctattgaat     4440

cagaatctgt gtacttgaac aaatgtgtga atctcaaata tctcaaagca aaagaaaaag     4500

tgttctagag tgttgttgct tttttaaaaa aagcgctgaa gttagaccaa ggtatacagt     4560

tttgttctaa cagacattta ggttaattgt aaagataagg aatgcattat gggtcaaaaa     4620

tcaaacattc ctctcatgtt atgtatattt tgttcctgtt atattggctt tattttcaaa     4680

attgtagttt gtagtattag tttcctttta ttggtattct tgcatatact attcattcaa     4740

taaatgactt atgactttca taaaaaaaaa aa                                   4772


<210>  950
<211>  1538
<212>  DNA
<213>  homo sapiens

<400>  950
ccgtgcaccg tgtgtgcgcg cggcgttgaa atgccctgca cgtcggggca gcgggacaga       60

tcccagggtg cccagggagt ctccaagtgc ctcactcctc ccgccgcaaa catgacagag      120

aactccgaca aagttcccat tgccctggtg ggacctgatg acgtggaatt ctgcagcccc      180

ccggcgtacg ctacgctgac ggtgaagccc tccagccccg cgcggctgct caaggtggga      240

gccgtggtcc tcatttcggg agctgtgctg ctgctctttg gggccatcgg ggccttctac      300

ttctggaagg ggagcgacag tcacatttac aatgtccatt acaccatgag tatcaatggg      360

aaattacaag atgggtcaat ggaaatagac gctgggaaca acttggagac ctttaaaatg      420

ggaagtggag ctgaagaagc aattgcagtt aatgatttcc agaatggcat cacaggaatt      480

cgttttgctg gaggagagaa gtgctacatt aaagcgcaag tgaaggctcg tattcctgag      540

gtgggcgccg tgaccaaaca gagcatctcc tccaaactgg aaggcaagat catgccagtc      600

aaatatgaag aaaattctct tatctgggtg gctgtagatc agcctgtgaa ggacaacagc      660

ttcttgagtt ctaaggtgtt agaactctgc ggtgaccttc ctattttctg gcttaaacca      720

acctatccaa aagaaatcca gagggaaaga agagaagtgg taagaaaaat tgttccaact      780

accacaaaaa gaccacacag tggaccacgg agcaacccag gcgctggaag actgaataat      840

gaaaccagac ccagtgttca agaggactca caagccttca atcctgataa tccttatcat      900

cagcaggaag gggaaagcat gacattcgac cctagactgg atcacgaagg aatctgttgt      960

atagaatgta ggcggagcta cacccactgc cagaagatct gtgaacccct ggggggctat     1020

tacccatggc cttataatta tcaaggctgc cgttcggcct gcagagtcat catgccatgt     1080

agctggtggg tggcccgtat cttgggcatg gtgtgaaatc acttcatata tcatgtgctg     1140

taaaataaga actagctgaa gagacaacca aagaagcatt aaggcaggtt gatgctgatg     1200

ggaccataaa atatttttac actcaacctg agcggttatt cttgacactc ttaacagaat     1260

tttttcaatt gttttccaga actttagtat atgcaaatgt actgaaaggg tagttcaagt     1320

ctaaaatgcc ataacccctt tattatttgt tattttttat ttgcattgct ttgccataag     1380

tcttcccttg cttgtatctt ccaaagctat tttgaaataa acatgaaaat ttacagtttg     1440

ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                             1538


<210>  951
<211>  4796
<212>  DNA
<213>  homo sapiens

<400>  951
tccggaggcg agccgagcgc ggtggtgagg ccgcctcagc gaaaaaaatg tccgcctgaa       60

gagacccaca agttctattc ggggggaccg acagcccgcc ccgggaggaa ggggcggcca      120

ggcccgaaag ccgcctcccc ctcccagacc cgagagctcg tgcggggcaa agtgaaccga      180

gccgctgggc ggtgcaaggg gaagcccaag cccgttctcc cggccaaagt gaactttaat      240

cggggtggtt ggatgcggag acggggcggc agaagtggcc gaagatgaat ccccagcaac      300

aacgcatggc cgctataggg accgacaagg agctgagcga cctactggac ttcagtgcga      360

tgttttcccc acctgttaat agtgggaaaa ctagaccaac tacactggga agcagtcaat      420

tcagtggatc aggtattgat gaaagaggag gtacaacatc ttggggaaca agtggtcaac      480

caagtccttc ctatgattca tctagaggtt ttacagacag ccctcattac agtgatcact      540

tgaatgacag tcgattagga gcccatgaag gcttgtcccc aacacctttc atgaactcaa      600

atctgatggg aaaaacatca gagagaggct cattttccct gtacagcaga gatactggat      660

taccaggctg tcaatctagt ctcctgagac aagatctggg gcttgggagc ccagcacagc      720

tatcttcttc aggaaaacct gggacagcat actattcatt ctctgctaca agttccagga      780

ggagaccact ccatgactct gcagcgcttg atcccttgca agcaaaaaaa gtcagaaagg      840

tgcctcctgg tttgccttct tctgtatatg caccatcccc aaattcagat gatttcaacc      900

gtgaatctcc tagttatcca tctcctaagc caccaaccag tatgttcgct agcactttct      960

ttatgcaaga tgggacccac aattcttctg acctttggag ttcatcaaat gggatgagcc     1020

agcctggttt tggtggaatt ctggggacct ccacttccca catgtctcaa tccagtagtt     1080

atggcaacct tcattcacat gaccgcttga gttatcctcc acactcagtt tcaccaacag     1140

acataaacac gagtcttcca ccaatgtcca gctttcatcg cggcagtacc agcagttcac     1200

cttacgttgc tgcctcacac actcctccca tcaatggatc agacagcatt ctaggaacca     1260

gagggaatgc tgctggaagc tcacagacag gtgatgcact tggaaaggct ttggcatcta     1320

tttattctcc tgaccatacc agcagtagtt ttccgtcaaa tccatcaaca ccagttggat     1380

caccttcacc tctcacaggt accagtcagt ggccaagacc tggagggcaa gcaccttcat     1440

ccccaagcta tgaaaactca ctccactccc tgaaaaatcg agttgagcag caacttcacg     1500

agcatttgca agatgcaatg tccttcttaa aggatgtctg tgagcagtct cgaatggagg     1560

atcgtttaga cagactggat gatgcaatcc atgtgctgcg gaaccatgct gtgggacctt     1620

ccaccagttt gcctgctggt cacagtgata tacatagttt attgggacca tcccataatg     1680

caccaattgg aagcctcaat tcaaactatg gaggatcaag ccttgttgca agcagtcgat     1740

cagcttcaat ggttggaact catcgggaag actctgtcag tctcaatggc aatcattcag     1800

tcctgtctag tacagtcact acttcaagca cagacctgaa ccataaaaca caagaaaatt     1860

atagaggtgg cttgcaaagt cagtctggaa ctgttgttac aacagaaatc aagactgaaa     1920

acaaagaaaa ggatgaaaac cttcatgaac ctccttcatc agatgacatg aagtcagatg     1980

atgaatcctc ccaaaaagat atcaaggttt catctagagg cagaacaagc agtactaatg     2040

aagatgagga tttgaaccct gaacagaaga tagaaaggga gaaggagagg cggatggcta     2100

acaatgccag agaacgctta cgcgtgcggg atattaatga agcattcaaa gagcttggcc     2160

gaatgtgtca gcttcacttg aagagtgaaa aaccccaaac aaaactcctt attcttcatc     2220

aagccgtggc agtcatcctt agtctagaac agcaagtcag agagaggaac cttaacccca     2280

aagcagcctg ccttaagaga agggaagaag aaaaagtttc tgccgtatcg gcagagccgc     2340

caaccacact gccaggaacc catcctgggc ttagtgaaac taccaaccct atgggtcata     2400

tgtaaacatc agccagttcc agagttatca gtaggctaga tagaaggtga cctctcctca     2460

taaggacttg gacaactcag attatctgaa gacacaaacc tgacaggagg gagaagaaaa     2520

aacaaaacac ttgaaccaag aaactcaaat gtaatcctac gatcaaagca actggtcaac     2580

acttccatca gaagtgaaga taggaagctc atcagataga acatcagccc atgagatgtt     2640

tgcaacaaat cttttgttgc aagcagtgtg tcgcttctgc acaatcagag actgtctcga     2700

tctctccact caccgtggaa gttgccttgt gcctaaactg aattgacaaa tgcattgtaa     2760

ctacaaattt tatttattgt tatgaaactg taaggtctac atataaaggg aaaaagttaa     2820

tgtggaaagc tgatctacac tcagctgatg ccagcataca ttaaagcggt tcacgtgcag     2880

agaacaaagc agtgacaacc attggccctt agcattcccg gcatacctat tagtgtctta     2940

aaaaggaagg gaaaagtctt ttgttgccct ctcctatcct cttgccatat gaatagcgtt     3000

ttccatgaaa taggaaaata ttacttggta tagcatttct cttgctctca ttttttgatt     3060

tatttttatt ttctctttgt gggtgttata tttgatctct aaatctgaac agtttatggt     3120

cacagtccag cctcctccgt gcagccctgt gtgctttgca catttacctt acagtggtaa     3180

gcagagacca tctgtgacca tagcctagct agcattttaa aaggggaaat tttgttctct     3240

aggttttccc ccaaataaac attgctttat ttctaataat aaccaagact tttcaagctt     3300

ctagatctca taggaaagct tgtaatagca aaattgtaaa ttacaaggga agaatctact     3360

ttttagaaat cgctttgttt tccaagcagt aagtactaca tacagtactt gtaaagtgtt     3420

agctgtaagt aagcacaaaa tacatttaaa atacaaagac gattttttca ggctgtgatt     3480

atggtgaaca taacaaaacc cagtagtcac caaggcaggt agtgtgataa atgaacacac     3540

cactctgagg ctaattacct aatggaatac aagagcaatg gtcacccgta tttccttatc     3600

ctagccttta tttctctgtc atttggatgg ctggtcaatg gggaagaatt gagtgggtga     3660

tttaatcaac tgcaaaccat ctgcccctgt cccaaaatga tgagccagat tagcattaaa     3720

ccagtacttg tcagtccatc ttaatactgt tcattaaggc actctctgtc tctaatcctt     3780

aggagttgtt ttaaaagaca taatcacttt gaacttccat gaaacctgtc ttccaccaca     3840

acaaccctgg gagagaaaaa catgctaaag gaggtatctt ggcttaataa ttccttatag     3900

ccaatatcaa cagtggcaat cagcacacag aggaaaggac ccaaatcact atgtagctta     3960

aagatttctg ttaatttgaa agaacaaaaa caagacagaa cttctggtac tctaatcagg     4020

atgattccta acaagtcagt catttgtgaa cttagtggac tttttggtta ctttaatttg     4080

catatattct ccagttacat cggactctat ctgtggcctt gttcttcatt tcagtgttaa     4140

tcagctaaac agaagttgtt gcttatgatg tgtgagtgaa catatgccac tgcctggcct     4200

ttttttcttc agagcttgtt gtctttttcg ctatattaga ctttgcagta tgcccagaag     4260

ctttccttca taaaatagaa agaaaaaaac atttggctta tttttcactg tagctagtct     4320

tttatacaat aatcttgtaa gaaaatttct tgaattctaa atattactct ttctagattt     4380

ttgaaatcaa aaagttttca gtaaaaagtt tcttacttta ttttattata ttaggtagta     4440

aaaaatgtag ggttatttac cataacctgt tcattaatat cagaaattta caatagcatt     4500

ttaagaccat agtaggattc tagcataccg tgtagtacct atggagtatt gtaagagcta     4560

attgttggag atgaattgct tctcatcttg ttctccagtt tccattgttg gtttattgca     4620

gatttgtatc ctgtgtcaaa ttcaaggtat tattgataaa ccttttcaac cagcagcaag     4680

aagttcaaat ttttttctgt cactgtaaca gaaaacacaa tatgtatata acatttatgt     4740

agcaataaat gtgccatctt ttttttaaca cagtaaaaaa aaaaaaaaaa aaaaaa         4796


<210>  952
<211>  2200
<212>  DNA
<213>  homo sapiens

<400>  952
agccaggctg ccaactcatt cgggagcccg gggcatgaac ggctacggct ccccctacct       60

gtacatgggc ggcccggtgt cgcagccgcc acgggcgccc ctgcagcgca cgcccaagtg      120

cgcgcgctgc cgcaaccatg gcgtcctgtc ctggctcaag ggccacaagc gttactgccg      180

cttcaaggac tgcacctgcg agaagtgcat cctcatcatc gagcggcagc gggtcatggc      240

tgcgcaggtg gcgctgcgcc ggcagcaggc caacgagagc ttggagagcc tcatccccga      300

ctcgctgcgc gctctgccag ggcccccgcc gccgggggac gccgtcgccg ccccgcagcc      360

gccgccagcc tctcagccgt cgcagccgca gccgccgcgc cctgctgccg agttggccgc      420

ggccgccgcg ctgcgttgga ctgccgagcc gcagcccggg gctctgcagg cgcagctcgc      480

caagccagat ttgactgaag aacgacttgg agacggcaag tcggcagaca atacagaggt      540

cttcagtgac aaagacactg accagaggag ttccccagat gtggcaaaga gtaagggctg      600

cttcacccct gagagccctg agatagtgtc cgtggaggaa gggggatacg ctgtccagaa      660

aaacggaggc aaccccgaga gccgccctga cagccccaag tgtcacgcgg agcagaatca      720

cctcctgatt gagggcccct cggggactgt ttctctgccc ttcagcttga aagccaacag      780

accgccgctt gaagtgttaa aaaagatatt ccccaaccag aagccaacgg tgcttgagct      840

catcctcaag ggctgtggcg gggacctggt gagcgccgtg gaagtccttc tgtccagccg      900

atcctcagtc acgggagcag agcgaacttc cgcagaacct gagagtctag cgttgccctc      960

caatgggcac atctttgaac acaccttgag ctcctacccc atctcgtctt ccaaatggtc     1020

tgtgggatca gcctttcgag tcccagacac gttgaggttt tctgccgact ctagcaacgt     1080

tgtccccagt cccttggctg ggcctctgca gccccctttc ccccagccac cccggtaccc     1140

gctgatgctg aggaatactt tggcgagaag ccagtcgagc ccctttttgc ccaatgatgt     1200

caccctgtgg aacaccatga cgctgcagca gcagtatcag ctgaggtccc agtatgtcag     1260

tcctttcccc agtaactcta ccagcgtctt cagaagctcg cccgtccttc ctgcccgcgc     1320

cacggaagac cctcggattt ccatccctga tgatgggtgt ccatttgtgt caaagcagtc     1380

catttacacc gaggacgact atgacgagag gtctgactcc tcagactcta gaacactcaa     1440

cacatcatct taaagtggtg ctggatgggt ggtggccagg tgacattttc tgtgcgtttt     1500

gaccctgagg catctgagga gaggccacat cttgtgtatg ccctttcctt ctgtttgaca     1560

aagtgactgt gcttgattct atacattagc aataaaaaca taacttattt aacttcttgc     1620

acttcactgg aaaatgccaa atagctctgt tctgtggctt tagtgctgaa tgtttattgt     1680

aaaagagagt ctaatgttaa gaatagtctt gggaaggctg ggtccgtgga agatttattt     1740

ggggatgtaa agctgaaggt cagccttgca cctaaaccca acctggaatg ttaaatgaaa     1800

taatatactt gaatgcaatt ttgtaaaagt ggattcctca ggatatgtga aacctaaagg     1860

aagtggttct gttgcaaatg gactataaac agggacatta tattcttaca ctaaaaatcc     1920

ttgcatttta aagagagatg cacttaagaa tagagtgaac tgctcatatg cttatttaag     1980

cttggacagt tttcagagac aaaccccatt aagaattact cttttcacat ggctgaatcg     2040

aaacatgtgt aatgtcaatg taaaaccaat cacagctgtg aactgcatga aatgtattgt     2100

gaaacgaaca caagattaag ctttgtcagg ttaatgtagc atgttaagga ctctagaaaa     2160

aaataaacta aggagacgag aaaaaaaaaa aaaaaaaaaa                           2200


<210>  953
<211>  4012
<212>  DNA
<213>  homo sapiens

<400>  953
agcgggacag acgagcggga ggggcagcgt gcggggagct gggggcgggg cgcggccgca       60

gctccgtttc cggtggctcg tcgcgctcgc tcactccagc tgcagccact ctcgcccgtg      120

gctgcttcct ccatcctggt attttttgga gcttccatcc tggttcttcc aaagtgcccg      180

gacccaaaac aggaaagtgt tgcggagata ggaacatggg agagaaacaa tctgggtaac      240

atgaaagtga tgctggttgc taagggaagg caacttgatt ctgtgggaag ggctgtagct      300

gatccatccg ttgtctagat ttgagtatga gcacagtgga agaggattct gacacagtaa      360

cagtagaaac tgtgaactct gtgactttga ctcaggacac agaagggaat ctcattcttc      420

actgccctca gaatgaagcg gatgaaatag actcagaaga tagtattgaa cctccacata      480

aaaggctttg tttgtcctct gaggatgatc agagtattga tgattctact ccttgcatat      540

cagttgttgc acttccactt tcagaaaatg atcagagctt tgaagtgacc atgactgcaa      600

ccacagaagt agcagatgat gaggttactg aggggactgt gacacagata cagattttgc      660

agaatgagca actagatgaa atatctccct tgggtaacga ggaagtttca gcagttagcc      720

aagcatggtt tacaactaaa gaagataagg attctctgac taataaagga cataaatgga      780

agcaggggat gtggtccaag gaagaaattg atattttgat gaacaatatt gaacgctatc      840

ttaaggcacg cggaataaaa gatgctacag aaatcatctt tgagatgtca aaagacgaaa      900

gaaaagattt ctacaggact atagcatggg gtctgaaccg gcctttgttt gcagtttata      960

gaagagtgct tcgcatgtat gatgacagaa accatgtggg aaaatataca cctgaagaaa     1020

ttgagaagct caaggagaaa aaggcaattg ctgcctgttt ttttttcacc cacagacaac     1080

tgtggacccc aaaaaaaggc cacactttca aactttggct ctcaaagtat tgctgcccac     1140

aacttccaaa ccagtcaaat gggaagaaga agaatgaaga ataaatgatg aaattaaaag     1200

ggagaaaaca attgaaccaa atgctgattg gcagactctt gttttaggct ccggataaag     1260

catggcaatg actgggcaac aataggggcg gcgctaggaa gaagtgcatc ttctgtcaaa     1320

gatcggtgcc gactgatgaa ggatacttgc aacacaggga agtggacaga agaagaagaa     1380

aagagacttg cagaagtggt tcatgagttg acaagcactg agccaggtga catagtcaca     1440

cagggtgtgt cttgggcagc tgtggctgaa cgagtcggta cccgctcaga aaagcaatgt     1500

cgttctaaat ggctcaacta cctgaattgg aaacagagtg ggggtactga atggaccaag     1560

gaagatgaaa tcaatctcat cctcaggata gcagaacttg atgtagctga tgaaaatgac     1620

attaactggg atctgttagc tgagggatgg agtagtgtcc gttcaccaca atggctacga     1680

agtaaatggt ggaccatcaa aaggcaaatt gcaaaccata aggatgtttc gttccctgtc     1740

ttaataaaag gtcttaaaca gttacatgag aaccaaaaaa acaacccaac gcttttggag     1800

aataaatcag gatctggagt tccaaacagt aataccaatt ccagtgtgca gcatgttcag     1860

ataagagttg cccgcttgga agataataca gccatctctt ctagccccat ggcagcattg     1920

cagattccag tccagatcac ccatgtttct tcagcagact ctcctgctac cgttgactca     1980

gaaacaataa cactaaacag tggaacacta cagacatttg agattcttcc ctctttccat     2040

ctacagccca ctggcactcc aggcacctac ctacttcaaa caagctcaag ccaaggcctt     2100

cccctaactc tgactgctag tcccacagta accctgacag ctgctgctcc tgcttctcct     2160

gaacagatta ttgttcatgc tttatcccca gaacatttgt tgaacacaag tgataatgtt     2220

acagtgcagt gtcacacacc aagagtcatc attcagactg ttgccacaga ggacatcact     2280

tcttccatat cccaagcaga actgacagtc gatagtgata ttcagtcatc tgattttcct     2340

gagcctccag acgccctaga agcagacact ttcccagatg aaattcatca ccctaagatg     2400

actgtggagc catcatttaa tgatgctcat gtatccaaat tcagtgacca aaatagcaca     2460

gaactgatga atagtgttat ggtcagaaca gaagaagaaa tctctgacac cgaccttaaa     2520

caagaggaat caccctctga tttagccagt gcttatgtta ctgagggttt agagtctccc     2580

actatagaag aacaagttga tcaaacaatt gatgatgaaa caatacttat cgttccttca     2640

ccacatggct ttatccaggc atctgatgtt atagatactg aatctgtctt gcctttgaca     2700

acactaacag atcccatact ccaacatcat caggaagaat caaatatcat tggatcatcc     2760

ttgggcagtc ctgtttcaga agattcaaag gatgtcgaag atttggtaaa ctgtcattag     2820

aataattctt agaaataggc agttcaagca aagaaggcac actgttaatt acaacctctt     2880

caaagaaata ggagcaaccc ccaagaggct taatttacca atttaaatag ccacagtcct     2940

taagccacac acattgttgc tgctatgact ttttacctcc tttaaacaca tcatctgagg     3000

ttgagtttta tgacagtatg tagttgagtg gaggctggga gttttaagca taaatccctg     3060

tttagtgtta catgggaata aggaatttca ttcacttcag ccactaagaa aagtttagaa     3120

tcacgaaagc ttaactgctg tggtttaaag tacagtttct ctaaagatca gacatggcac     3180

tgtctcctct caagcctggt tgtagttcag atgagtcttt tcaacatggt cttcaacatg     3240

gtctagagct taccagtgat cttctgatct tcaagaagac taagtttgag acttgaccag     3300

catacaagta tagagaccta ggaggtggtc ttgtggtggt acatttggtt aacccattgc     3360

tggcagtggg agctgattta ggcagggtaa acaggaaagc attaaaagtt aaaattcact     3420

acaggttttt tgttactttt aaagggaata tggataagca tagtaacaaa acccaccaga     3480

atctaagcag ttttcacccc ctcagaaacc actgtcatta gtttacaaag ttagcacttt     3540

gaagtaaaac taaatgagga aggaagtaat gttacctatc cttgatacca tgaccattta     3600

ttagatgttt tgctatataa attaccgaga gaatagtttg tcatccactt agtgtgttag     3660

ctggtggggt acaatataac ctctcatctc aggctatttt aaaaaaacaa tatttgcttc     3720

tataacaaaa ggaaacaaat ctaagaatca ttcctgtact acagaagggt taaggcaaag     3780

gtagcctttt gggcttttta atgaatatga cccctataga aaagtcaaga aaaaaaaacc     3840

cttgtataaa ttattttatt tattattgta attagatctt cacaaagttg tcttttcact     3900

gtgttttgtc aacgtgaaat taaattgtag ttataagcaa aagttggttg cctagggaac     3960

aattgtatat tcagtttaac agaaataaaa gaatatttgt cttaagatgc aa             4012


<210>  954
<211>  782
<212>  DNA
<213>  homo sapiens

<400>  954
aaggcgcgca gcgctgggcg caaagcgcca gtctccgcct tgcgagctca gagtgtgccc       60

gctgcgccgc cgctgtccgt acctgccgcc gccgccaccg ccaccatgcc caacttcgcc      120

ggcacctgga agatgcgcag cagcgagaat ttcgacgagc tgctcaaggc actgggtgtg      180

aacgccatgc tgaggaaagt ggccgtagcg gctgcgtcca agccgcacgt ggagatccgc      240

caggacgggg atcagttcta catcaagaca tccaccacgg tgcgcaccac tgagatcaac      300

ttcaaggtcg gagaaggctt tgaggaggag accgtggacg gacgcaagtg caggagttta      360

gccacttggg agaatgagaa caagatccac tgcacgcaaa ctcttcttga aggggacggc      420

cccaaaacct actggacccg tgagctggcc aacgatgaac ttatcctgac gtttggcgcc      480

gatgacgtgg tctgcaccag aatttatgtc cgagagtgaa ggcagctggc ttgctcctac      540

tttcaggaag ggatgcaggc tcccctgagg aatatgtcat agttctgagc tgccagtgga      600

ccgccctttt cccctaccaa tattaggtga tcccgttttc cccatgacaa tgttgtagtg      660

tcccccaccc ccacccccca ggccttggtg cctcttgtat ccctagtgct ccatagtttg      720

gcatttgcac ggtttcgaag tcattaaact ggttagacgt gtctcaacct ttaaaaaaaa      780

aa                                                                     782


<210>  955
<211>  9794
<212>  DNA
<213>  homo sapiens

<400>  955
tgtttccgtg cgcggccgct gcgcactcgg cactgggcgg cgctggctgg ctccctggct       60

gcggctcctc agtcggcggc ggctgctgct gcctgtggcc cgggcggctg ggagaagcgg      120

agtgttggtg agtgacgcgg cggaggtgta gtttgacgcg gtgtgttacg tgggggagag      180

aataaaactc cagcgagatc cgggccgtga acgaaagcag tgacggagga gcttgtacca      240

ccggtaacta aatgaccatg gaatctggag ccgagaacca gcagagtgga gatgcagctg      300

taacagaagc tgaaaaccaa caaatgacag ttcaagccca gccacagatt gccacattag      360

cccaggtatc tatgccagca gctcatgcaa catcatctgc tcccaccgta actctagtac      420

agctgcccaa tgggcagaca gttcaagtcc atggagtcat tcaggcggcc cagccatcag      480

ttattcagtc tccacaagtc caaacagttc agtcttcctg taaggactta aaaagacttt      540

tctccggaac acagatttca actattgcag aaagtgaaga ttcacaggag tcagtggata      600

gtgtaactga ttcccaaaag cgaagggaaa ttctttcaag gaggccttcc tacaggaaaa      660

ttttgaatga cttatcttct gatgcaccag gagtgccaag gattgaagaa gagaagtctg      720

aagaggagac ttcagcacct gccatcacca ctgtaacggt gccaactcca atttaccaaa      780

ctagcagtgg acagtatatt gccattaccc agggaggagc aatacagctg gctaacaatg      840

gtaccgatgg ggtacagggc ctgcaaacat taaccatgac caatgcagca gccactcagc      900

cgggtactac cattctacag tatgcacaga ccactgatgg acagcagatc ttagtgccca      960

gcaaccaagt tgttgttcaa gctgcctctg gagacgtaca aacataccag attcgcacag     1020

cacccactag cactattgcc cctggagttg ttatggcatc ctccccagca cttcctacac     1080

agcctgctga agaagcagca cgaaagagag aggtccgtct aatgaagaac agggaagcag     1140

ctcgagagtg tcgtagaaag aagaaagaat atgtgaaatg tttagaaaac agagtggcag     1200

tgcttgaaaa tcaaaacaag acattgattg aggagctaaa agcacttaag gacctttact     1260

gccacaaatc agattaattt gggatttaaa ttttcacctg ttaaggtgga aaatggactg     1320

gcttggccac aacctgaaag acaaaataaa cattttattt tctaaacatt tctttttttc     1380

tatgcgcaaa actgcctgaa agcaactaca gaatttcatt catttgtgct tttgcattaa     1440

actgtgaatg ttccaacacc tgcctccact tctcccctca agaaattttc aacgccagga     1500

atcatgaaga gacttctgct tttcaacccc caccctcctc aagaagtaat aatttgttta     1560

cttgtaaatt gatgggagaa atgaggaaaa gaaaatcttt ttaaaaatga tttcaaggtt     1620

tgtgctgagc tccttgattg ccttagggac agaattaccc cagcctcttg agctgaagta     1680

atgtgtgggc cgcatgcata aagtaagtaa ggtgcaatga agaagtgttg attgccaaat     1740

tgacatgttg tcacattctc attgtgaatt atgtaaagtt gttaagagac ataccctcta     1800

aaaaagaact ttagcatggt attgaaggaa ttagaaatga atttggagtg ctttttatgt     1860

atgttgtctt cttcaatact gaaaatttgt ccttggttct taaaagcatt ctgtactaat     1920

acagctcttc catagggcag ttgttgcttc ttaattcagt tctgtatgtg ttcaacattt     1980

ttgaatacat taaaagaagt aaccaactga acgacaaagc atggtatttg aattttaaat     2040

taaagcaaag taaataaaag tacaaagcat attttagtta gtactaaatt cttagtaaaa     2100

tgctgatcag taaaccaatc ccttgagtta tataacaaga tttttaaata aatgttattg     2160

tcctcacctt caaaaatatt tatattgtca ctcatttacg taaaaagata tttctaattt     2220

actgttgccc attgcactta cataccacca ccaagaaagc cttcaagatg tcaaataaag     2280

caaagtgata tatatttgtt tatgaaatgt tacatgtaga aaaatactga ttttaaatat     2340

tttccatatt aacaatttaa cagagaatct ctagtgaatt ttttaaatga aagaagttgt     2400

aaggatataa aaagtacagt gttagatgtg cacaaggaaa gttattttca gacatatttg     2460

aatgactgct gtactgcaat atttggattg tcattcttac aaaacatttt tttgttctct     2520

tgtaaaaaga gtagttatta gttctgcttt agctttccaa tatgctgtat agcctttgtc     2580

attttataat tttaattcct gattaaaaca gtctgtattt gtgtatatca tacattgttt     2640

tcaataccac ttttaattgt tactcatttt attcactaag ctcgataaat ctaacagtta     2700

ctcttaaaaa aaaaaaaaaa agactaaggt ggattttaaa aattggaaac tgacataatg     2760

ttaggttata atttctcatt tggagccggg cgcagtggct cacgcctgta atcccagcac     2820

tttgggaggc caaggtgggt ggatcacctg tggtcaagag ttcaagacca gcctggccat     2880

catggtgaaa ccccatctct actaaaaata caaaaattag ccaggcgtgg tggctggcgc     2940

ctgtaatccc agctactcag gaggttgagg cagcagaatt gcttgaaccc aggaggcaga     3000

gggttgcagt gagccgagat agcaccattg cactccagcc tgggcgactc catctcaaaa     3060

aataaaaata aaaaaaatgt ctcatttggg aaggaaattc cttttaaaaa agagttgaga     3120

cacttagaaa actaatgttt tatatttagt caagagttat ttaagaaagt caagcttgtt     3180

taacaacaaa atatgaagat ttaagtgtta attgctggat ccattttaaa ataagatttt     3240

aattaacatt tgtaaatggt atattttcgt ttgtaacaaa ccattgtctt ttttcaagga     3300

tgaacagagt ttatgaagga gcatcattct aagaattaag tgatgtagtc tttatgtttg     3360

gacagttcac cagattctca agaaggcttt caaacaacta taaagtttga tgtttgtcct     3420

gctgagctaa tggggaaagt tatagcataa aaattgtgta accgcataga tatgtcattt     3480

ttaaaaactg gtttaacaga aatcaagcaa agtcacaaat atgttcacaa gttggaatta     3540

tttattgagt caaaatgtcg aatcgaacat tttgaatgaa gtaagtgtta taaatgaaaa     3600

attgcctgat gtttagcagt ttgtattctc taaagctttt tttcaaaagt tcaggctttc     3660

tacttactgg gaagttggtg gtcctcttag tccctgataa atcaaggcaa tcacattcat     3720

gtgagctgga tgaatttata agttataaag accttatcct tcataccttg aggatgattg     3780

cactggtttt gaagtcagtt gcttaatgat gaggtgagaa atgtatcctg ttgctaaatc     3840

tgtcttagac ccttggtgaa acttgaagat ttcagtttat aaagataaaa tcaagcatct     3900

tttgtgcagt tttctttttt taatgcaaga atggtgggga ggtttgtttg taagcatgaa     3960

actttgagaa tctttattaa gaaaatgaca taatttttaa aaaccttgta gccaagaaca     4020

tatgtggcca cattaccagt aataaatgtt tttctcttta tattggccaa aagggaataa     4080

aaatgtcatc ataggaattt gtacatatgc tactgatttg cctagaaaat agcaagtttg     4140

atattgctca ctttgcaaat atagggccat gtggcacttt tatctatagg acagattaat     4200

aaaaatgaag tggggagggg tttatttttg atatattact cttatgagtt ttcaagcttt     4260

gataatgttt aactgaaaag tggcttagaa agggctagat ccaatgtgtt cattattaaa     4320

taattgctat cagatacaat tttaagttca ttctttttca aactcaagta ccatattggc     4380

aaccataata ttgtcatagg tgctctcttc atttagatat tcttgggggg ggtggcattt     4440

gtataatata tgtgtacata tatatatata tatatatata tacatacagt atataatcta     4500

aagctctgag agctcttaag tcaggaatgc tgagtattat agtatattga ggtcagatga     4560

aattttacat ttttgtgtgt tctgttgcat tccttctggt agtttctatg actgcattac     4620

tccagcactc atgattgatt ttatcttcta attttcttcc aagtatttta ttttttatta     4680

gttttctttg gcttgatact tttaaatatg ttactagtca cttgaaagcc tctcccccaa     4740

aagtatttgg tttgtatgct ttgtctgtgg cagctataac agtggtaaga acattttgaa     4800

gatagctttt taaaggaacc actgattttt tcaaaaatca tcctggggga ggaattttgg     4860

catttcattt gagcagggat tttgtcagaa aatgtgtttt gatggtaggt cagcagcagt     4920

gctagtctct gaaagcacaa taccagtcag gcagcctatc ccatcagatg tcatctggct     4980

gaagtttatc tctgtctctc aggataaatc cctgtaggac aaatccctac tatcatttct     5040

accttttggg gtgacatgtg gaatcataca aaggcttagg aagaaatacg tttgtttaaa     5100

ccaggatgct ttacttactt gaagtgactt caatctagat ttcttttaat atttaacaaa     5160

tttttaattc tatgatcagc cacagtcagc tattaccata aattggtctc tgtttatttt     5220

gaagatcacg gctgcttcat tttgcaggat taagtagggc taatgtatct taaagttaag     5280

atcttgaatt aaagtgagtt ttagaaatag tgttacatac cttttcagtt gttttcaaga     5340

ggctttattt ttgttgcctt tgtagccctg aaagctgttg gtatattttt tccctcatgg     5400

acccaataga aaagttgtat atttatttgg attatattta cattctgtcc tttgtaaatg     5460

tttggtgtaa cttgcacttt tttaaatgac ccagtttggg tattagcaac ttaagaaatt     5520

ccctcatcaa gtaattctca actttttagt ctttctcctc tcttcaaatc atgtgacttt     5580

ttaaatggaa gtttttcatt gattaaaata ttttagcacc taaaagctag ccttaaaaac     5640

agctgtaaaa gaaaaacatc aggaaattag atatgactag cccagttaat taaaagacgg     5700

gctcaaacct tgttttattc tttttcatct tggatgaaga ttgaagggaa aataactcaa     5760

gtgcataata tttattttca atttttaatg agactttatc ctcatcacaa cattaatact     5820

gtacatagta tgccaaaata tccattaatt tgtctagaat agtacaagac tttttaaagc     5880

aattgtcctc acagagacca catgtaatat actgaaatat gttcattttt aatggctttg     5940

ttaacatcaa agaaatgctg cctaaatttg atttcagatg aggaaggaga aagtaaagtg     6000

tgcatagtaa ggctgtaggt gaagagttgt gagataaata gttcactcag ttgtacaaag     6060

cacaactaga actttttgtt gggaggctta catacatctt gaatattctt aatgtaataa     6120

tgttgactat taagttggct acacagtcac tgtatgtact aggaactggt ttccttgaca     6180

ttctagaatc aatggctagg agaggcatta atctttgagg ggctgaacat atcatgaagc     6240

tgagtcagta tggaaaattt tcaaataaac agggtgctga agttccatct gtctcatctg     6300

cttatgataa gttcttattg attagtgaat gtagcttaag cctttgtatg tgtcctcagg     6360

gggcagaccg actttaagag ggaccagata acgtttgaat ggagggatta tatttcaggt     6420

gttttagctt gaaatttatt ttttaaaaaa agaaaaattt aaaaaatata taaataaaat     6480

agaacaaagc cggtgatgca agttgatatt ataaacaggc agttttagca cagaaagaaa     6540

atactgacct gtctgcattc tggtacggtg ggtgcaggtc ccagctgggt atgacatgat     6600

acatttttaa ttattctcac cagcaagtaa aaggaaaatg aacaatcttt tggaattgtc     6660

tttgaaaagg atcaaagagt aggaaattca catttgacct aacattactt gcctatagaa     6720

gtatggcatt tccaagcttt tgtctgagga gcatctcaga gaagtgagag taaatctgag     6780

ttagcttaaa aattggtagg gaggaagaaa atctctgcaa ataatgattt tatgtttgtt     6840

ggccaagtga aatgatctat cattgtgttt gggaggtttt attttcttat gtttttaaaa     6900

ttggtaaatg ctttatagat gtatttttat ccaagtgcca ctccaatttg tgtatgtaat     6960

aaaattattt atattaaaag tgggaaataa ttgtcaacat tttttttgag tatagattta     7020

ttaggggtgg caaagaagag tgctagttag cagttttcca tgtaaagttg tccttgactg     7080

atttgtccac atgtcagttg taactccccc actccctgca aaaggaatta tttctaaccc     7140

agatgtatca cttgaaactt tttagaagca aaataatcag ggaagttcct agaaaggtgt     7200

ttggcttttt ggtttttgag ggttggggta aagaagactt cccccacaac tgtcagcaca     7260

aaacagggta ttgattttta actctgatgt ttctattgga gttgaatact aaataaataa     7320

ctataatgag ggaaatacat ttctaataaa attccctaca ttctagaaac atccctgttt     7380

taattttttt atctaaatct ttttgtgctt tatgtgtaaa gaaaaaaatg tactgagtta     7440

caatgcattt tattaacact atgtacataa tagctgcttt gtgttcagaa tagtagcagt     7500

tgctttgtat attaaagtga tccttgtgaa tttgtgaaat attgtcataa agtgcttttt     7560

cttactgtaa tctttgtggt atcaactgtc ataatgctct ttttacacaa acatttatgt     7620

gcagtcacat aaacatgctt ttaaaaactc tgtaagtctc ttttttgggg atgggatctc     7680

tatattttgt tgggtttttt ttgctagtag tgtgaagcca tgttttattg gacttaaagt     7740

tacaatatat tacaagcttg tgttggaagg cagcaaaact aattcagaca acaacatgtc     7800

ttcagttact ggatccctaa ttttcaggac aaaacctgtt tttcaataag attgaacagt     7860

gcctatttgt ggatttggag atgttactgt caagatgact aatggagaca tacgaccagc     7920

tgtgtctgat gtcataaaac acgtgttcac tgaaaggaca ataagactat ataccttctc     7980

aggtcccctt gcaattctaa aactctgtga tcatataaat tggaaggaaa ggggagggga     8040

tatggttaat ctttgcttaa gctgtaagaa taaaaaagtt atctcctata ctattaactt     8100

ctgaaataag ttctgagacg agacatctga aaataagcag ctgcattatt tgtatgtttc     8160

ttcactgcca agatgtgttc aagcctgcta tacctgccat tgtattggaa ggcttaatga     8220

atttcattta ttttctgcaa caacgattac agaatttatt gcacaaaatg agacattttg     8280

agagtgatat taattacatg agggacaata ggcatgaact aggattgttc taagcaaatc     8340

ggaatcgggt caccctgcca cgttcaggtg cttggacctt caggaaaaga ttgcccatct     8400

tgtcatttga ccaggcactg aagtgacaag accatccttg agaagtcaca tccaaagata     8460

aaattctgat ccatttctag ttttagtgtt tcgccactga agacttaaca tatgtctttt     8520

acactcaggt tgcaaaacac aggcccaaga caaacttaac ttctccccca aatcttcctt     8580

ccgctggttt ttccatctcg taagtggtgc cactatccat ctgttaaatt gtttagggga     8640

aacctagaaa agcactacct taatcagtgt tatccttctt cttaactgtg cgtcctaatt     8700

tctccacatc tttcttaagt gcagtgacca aaccggatga gaattctaac acgggcctga     8760

catcaaatgg aaaggaagga taatgtccag gagttggaat gttatccttg tttttaatta     8820

agatgcaatt cacataaatt aactttttaa gtgaacaatt aagtggtagt acatccacaa     8880

tggtgtacaa ccaccacttc tatctagctc caaaacattc tcatcactcc aaaagtaaag     8940

tcccgttact ctccattttc tcctcccacc gcccttgtcc ctggcaacca ccaatctgct     9000

tcctgtttct ttggatttac atccgggtat ttcatgtgag actcatacac tgtgtattac     9060

ttctttcgtc tagctttaat gtgttgttga ggttgatcca ttgtaacatg ttatcactac     9120

ttcattcctt tttatagcta agtatacttt ttatagtaag tatgccattg tagatatata     9180

ccacaagttt atcgattcat ccagttgagt tgtttctact gtttggctaa tgttcatagt     9240

gctgttatga atgttcgtgt acaagtattt gagtccgtgt tttcaattat ttggggtata     9300

tgcctgggag tggagttgct gggtcatgtt gaaatcgcac atttaacttt ttgaggaact     9360

gtcaaacttt ccctcagcag ctgtaccgtt ttaccttcca ccattgatgt atgagggttc     9420

caatttctcc acaccttcac caacacttat tttgccattt taaaaattat agccatcctc     9480

atgggtgtgg tctctcattg tggttttgat ttgcatttcc ctgattacta atgatgtgga     9540

gcatcttttg ttgtctttgg ccatctgcgt atcttctttg aagaaatgtc tgttgaggtc     9600

ctttgttcat tgaaattttg ttgttgggtt ctgagttcct tatatattct gggtactagg     9660

cccttataat attttcgcct ataagttttt gctttataat gtcctcattg ttttcaaact     9720

tactttatgt aatatgtaca cttctaaaaa aaagaaacat ggaaaagggc aaactgtaaa     9780

aaaaaaaaaa aaaa                                                       9794


<210>  956
<211>  9752
<212>  DNA
<213>  homo sapiens

<400>  956
tgtttccgtg cgcggccgct gcgcactcgg cactgggcgg cgctggctgg ctccctggct       60

gcggctcctc agtcggcggc ggctgctgct gcctgtggcc cgggcggctg ggagaagcgg      120

agtgttggtg agtgacgcgg cggaggtgta gtttgacgcg gtgtgttacg tgggggagag      180

aataaaactc cagcgagatc cgggccgtga acgaaagcag tgacggagga gcttgtacca      240

ccggtaacta aatgaccatg gaatctggag ccgagaacca gcagagtgga gatgcagctg      300

taacagaagc tgaaaaccaa caaatgacag ttcaagccca gccacagatt gccacattag      360

cccaggtatc tatgccagca gctcatgcaa catcatctgc tcccaccgta actctagtac      420

agctgcccaa tgggcagaca gttcaagtcc atggagtcat tcaggcggcc cagccatcag      480

ttattcagtc tccacaagtc caaacagttc agatttcaac tattgcagaa agtgaagatt      540

cacaggagtc agtggatagt gtaactgatt cccaaaagcg aagggaaatt ctttcaagga      600

ggccttccta caggaaaatt ttgaatgact tatcttctga tgcaccagga gtgccaagga      660

ttgaagaaga gaagtctgaa gaggagactt cagcacctgc catcaccact gtaacggtgc      720

caactccaat ttaccaaact agcagtggac agtatattgc cattacccag ggaggagcaa      780

tacagctggc taacaatggt accgatgggg tacagggcct gcaaacatta accatgacca      840

atgcagcagc cactcagccg ggtactacca ttctacagta tgcacagacc actgatggac      900

agcagatctt agtgcccagc aaccaagttg ttgttcaagc tgcctctgga gacgtacaaa      960

cataccagat tcgcacagca cccactagca ctattgcccc tggagttgtt atggcatcct     1020

ccccagcact tcctacacag cctgctgaag aagcagcacg aaagagagag gtccgtctaa     1080

tgaagaacag ggaagcagct cgagagtgtc gtagaaagaa gaaagaatat gtgaaatgtt     1140

tagaaaacag agtggcagtg cttgaaaatc aaaacaagac attgattgag gagctaaaag     1200

cacttaagga cctttactgc cacaaatcag attaatttgg gatttaaatt ttcacctgtt     1260

aaggtggaaa atggactggc ttggccacaa cctgaaagac aaaataaaca ttttattttc     1320

taaacatttc tttttttcta tgcgcaaaac tgcctgaaag caactacaga atttcattca     1380

tttgtgcttt tgcattaaac tgtgaatgtt ccaacacctg cctccacttc tcccctcaag     1440

aaattttcaa cgccaggaat catgaagaga cttctgcttt tcaaccccca ccctcctcaa     1500

gaagtaataa tttgtttact tgtaaattga tgggagaaat gaggaaaaga aaatcttttt     1560

aaaaatgatt tcaaggtttg tgctgagctc cttgattgcc ttagggacag aattacccca     1620

gcctcttgag ctgaagtaat gtgtgggccg catgcataaa gtaagtaagg tgcaatgaag     1680

aagtgttgat tgccaaattg acatgttgtc acattctcat tgtgaattat gtaaagttgt     1740

taagagacat accctctaaa aaagaacttt agcatggtat tgaaggaatt agaaatgaat     1800

ttggagtgct ttttatgtat gttgtcttct tcaatactga aaatttgtcc ttggttctta     1860

aaagcattct gtactaatac agctcttcca tagggcagtt gttgcttctt aattcagttc     1920

tgtatgtgtt caacattttt gaatacatta aaagaagtaa ccaactgaac gacaaagcat     1980

ggtatttgaa ttttaaatta aagcaaagta aataaaagta caaagcatat tttagttagt     2040

actaaattct tagtaaaatg ctgatcagta aaccaatccc ttgagttata taacaagatt     2100

tttaaataaa tgttattgtc ctcaccttca aaaatattta tattgtcact catttacgta     2160

aaaagatatt tctaatttac tgttgcccat tgcacttaca taccaccacc aagaaagcct     2220

tcaagatgtc aaataaagca aagtgatata tatttgttta tgaaatgtta catgtagaaa     2280

aatactgatt ttaaatattt tccatattaa caatttaaca gagaatctct agtgaatttt     2340

ttaaatgaaa gaagttgtaa ggatataaaa agtacagtgt tagatgtgca caaggaaagt     2400

tattttcaga catatttgaa tgactgctgt actgcaatat ttggattgtc attcttacaa     2460

aacatttttt tgttctcttg taaaaagagt agttattagt tctgctttag ctttccaata     2520

tgctgtatag cctttgtcat tttataattt taattcctga ttaaaacagt ctgtatttgt     2580

gtatatcata cattgttttc aataccactt ttaattgtta ctcattttat tcactaagct     2640

cgataaatct aacagttact cttaaaaaaa aaaaaaaaag actaaggtgg attttaaaaa     2700

ttggaaactg acataatgtt aggttataat ttctcatttg gagccgggcg cagtggctca     2760

cgcctgtaat cccagcactt tgggaggcca aggtgggtgg atcacctgtg gtcaagagtt     2820

caagaccagc ctggccatca tggtgaaacc ccatctctac taaaaataca aaaattagcc     2880

aggcgtggtg gctggcgcct gtaatcccag ctactcagga ggttgaggca gcagaattgc     2940

ttgaacccag gaggcagagg gttgcagtga gccgagatag caccattgca ctccagcctg     3000

ggcgactcca tctcaaaaaa taaaaataaa aaaaatgtct catttgggaa ggaaattcct     3060

tttaaaaaag agttgagaca cttagaaaac taatgtttta tatttagtca agagttattt     3120

aagaaagtca agcttgttta acaacaaaat atgaagattt aagtgttaat tgctggatcc     3180

attttaaaat aagattttaa ttaacatttg taaatggtat attttcgttt gtaacaaacc     3240

attgtctttt ttcaaggatg aacagagttt atgaaggagc atcattctaa gaattaagtg     3300

atgtagtctt tatgtttgga cagttcacca gattctcaag aaggctttca aacaactata     3360

aagtttgatg tttgtcctgc tgagctaatg gggaaagtta tagcataaaa attgtgtaac     3420

cgcatagata tgtcattttt aaaaactggt ttaacagaaa tcaagcaaag tcacaaatat     3480

gttcacaagt tggaattatt tattgagtca aaatgtcgaa tcgaacattt tgaatgaagt     3540

aagtgttata aatgaaaaat tgcctgatgt ttagcagttt gtattctcta aagctttttt     3600

tcaaaagttc aggctttcta cttactggga agttggtggt cctcttagtc cctgataaat     3660

caaggcaatc acattcatgt gagctggatg aatttataag ttataaagac cttatccttc     3720

ataccttgag gatgattgca ctggttttga agtcagttgc ttaatgatga ggtgagaaat     3780

gtatcctgtt gctaaatctg tcttagaccc ttggtgaaac ttgaagattt cagtttataa     3840

agataaaatc aagcatcttt tgtgcagttt tcttttttta atgcaagaat ggtggggagg     3900

tttgtttgta agcatgaaac tttgagaatc tttattaaga aaatgacata atttttaaaa     3960

accttgtagc caagaacata tgtggccaca ttaccagtaa taaatgtttt tctctttata     4020

ttggccaaaa gggaataaaa atgtcatcat aggaatttgt acatatgcta ctgatttgcc     4080

tagaaaatag caagtttgat attgctcact ttgcaaatat agggccatgt ggcactttta     4140

tctataggac agattaataa aaatgaagtg gggaggggtt tatttttgat atattactct     4200

tatgagtttt caagctttga taatgtttaa ctgaaaagtg gcttagaaag ggctagatcc     4260

aatgtgttca ttattaaata attgctatca gatacaattt taagttcatt ctttttcaaa     4320

ctcaagtacc atattggcaa ccataatatt gtcataggtg ctctcttcat ttagatattc     4380

ttgggggggg tggcatttgt ataatatatg tgtacatata tatatatata tatatatata     4440

catacagtat ataatctaaa gctctgagag ctcttaagtc aggaatgctg agtattatag     4500

tatattgagg tcagatgaaa ttttacattt ttgtgtgttc tgttgcattc cttctggtag     4560

tttctatgac tgcattactc cagcactcat gattgatttt atcttctaat tttcttccaa     4620

gtattttatt ttttattagt tttctttggc ttgatacttt taaatatgtt actagtcact     4680

tgaaagcctc tcccccaaaa gtatttggtt tgtatgcttt gtctgtggca gctataacag     4740

tggtaagaac attttgaaga tagcttttta aaggaaccac tgattttttc aaaaatcatc     4800

ctgggggagg aattttggca tttcatttga gcagggattt tgtcagaaaa tgtgttttga     4860

tggtaggtca gcagcagtgc tagtctctga aagcacaata ccagtcaggc agcctatccc     4920

atcagatgtc atctggctga agtttatctc tgtctctcag gataaatccc tgtaggacaa     4980

atccctacta tcatttctac cttttggggt gacatgtgga atcatacaaa ggcttaggaa     5040

gaaatacgtt tgtttaaacc aggatgcttt acttacttga agtgacttca atctagattt     5100

cttttaatat ttaacaaatt tttaattcta tgatcagcca cagtcagcta ttaccataaa     5160

ttggtctctg tttattttga agatcacggc tgcttcattt tgcaggatta agtagggcta     5220

atgtatctta aagttaagat cttgaattaa agtgagtttt agaaatagtg ttacatacct     5280

tttcagttgt tttcaagagg ctttattttt gttgcctttg tagccctgaa agctgttggt     5340

atattttttc cctcatggac ccaatagaaa agttgtatat ttatttggat tatatttaca     5400

ttctgtcctt tgtaaatgtt tggtgtaact tgcacttttt taaatgaccc agtttgggta     5460

ttagcaactt aagaaattcc ctcatcaagt aattctcaac tttttagtct ttctcctctc     5520

ttcaaatcat gtgacttttt aaatggaagt ttttcattga ttaaaatatt ttagcaccta     5580

aaagctagcc ttaaaaacag ctgtaaaaga aaaacatcag gaaattagat atgactagcc     5640

cagttaatta aaagacgggc tcaaaccttg ttttattctt tttcatcttg gatgaagatt     5700

gaagggaaaa taactcaagt gcataatatt tattttcaat ttttaatgag actttatcct     5760

catcacaaca ttaatactgt acatagtatg ccaaaatatc cattaatttg tctagaatag     5820

tacaagactt tttaaagcaa ttgtcctcac agagaccaca tgtaatatac tgaaatatgt     5880

tcatttttaa tggctttgtt aacatcaaag aaatgctgcc taaatttgat ttcagatgag     5940

gaaggagaaa gtaaagtgtg catagtaagg ctgtaggtga agagttgtga gataaatagt     6000

tcactcagtt gtacaaagca caactagaac tttttgttgg gaggcttaca tacatcttga     6060

atattcttaa tgtaataatg ttgactatta agttggctac acagtcactg tatgtactag     6120

gaactggttt ccttgacatt ctagaatcaa tggctaggag aggcattaat ctttgagggg     6180

ctgaacatat catgaagctg agtcagtatg gaaaattttc aaataaacag ggtgctgaag     6240

ttccatctgt ctcatctgct tatgataagt tcttattgat tagtgaatgt agcttaagcc     6300

tttgtatgtg tcctcagggg gcagaccgac tttaagaggg accagataac gtttgaatgg     6360

agggattata tttcaggtgt tttagcttga aatttatttt ttaaaaaaag aaaaatttaa     6420

aaaatatata aataaaatag aacaaagccg gtgatgcaag ttgatattat aaacaggcag     6480

ttttagcaca gaaagaaaat actgacctgt ctgcattctg gtacggtggg tgcaggtccc     6540

agctgggtat gacatgatac atttttaatt attctcacca gcaagtaaaa ggaaaatgaa     6600

caatcttttg gaattgtctt tgaaaaggat caaagagtag gaaattcaca tttgacctaa     6660

cattacttgc ctatagaagt atggcatttc caagcttttg tctgaggagc atctcagaga     6720

agtgagagta aatctgagtt agcttaaaaa ttggtaggga ggaagaaaat ctctgcaaat     6780

aatgatttta tgtttgttgg ccaagtgaaa tgatctatca ttgtgtttgg gaggttttat     6840

tttcttatgt ttttaaaatt ggtaaatgct ttatagatgt atttttatcc aagtgccact     6900

ccaatttgtg tatgtaataa aattatttat attaaaagtg ggaaataatt gtcaacattt     6960

tttttgagta tagatttatt aggggtggca aagaagagtg ctagttagca gttttccatg     7020

taaagttgtc cttgactgat ttgtccacat gtcagttgta actcccccac tccctgcaaa     7080

aggaattatt tctaacccag atgtatcact tgaaactttt tagaagcaaa ataatcaggg     7140

aagttcctag aaaggtgttt ggctttttgg tttttgaggg ttggggtaaa gaagacttcc     7200

cccacaactg tcagcacaaa acagggtatt gatttttaac tctgatgttt ctattggagt     7260

tgaatactaa ataaataact ataatgaggg aaatacattt ctaataaaat tccctacatt     7320

ctagaaacat ccctgtttta atttttttat ctaaatcttt ttgtgcttta tgtgtaaaga     7380

aaaaaatgta ctgagttaca atgcatttta ttaacactat gtacataata gctgctttgt     7440

gttcagaata gtagcagttg ctttgtatat taaagtgatc cttgtgaatt tgtgaaatat     7500

tgtcataaag tgctttttct tactgtaatc tttgtggtat caactgtcat aatgctcttt     7560

ttacacaaac atttatgtgc agtcacataa acatgctttt aaaaactctg taagtctctt     7620

ttttggggat gggatctcta tattttgttg ggtttttttt gctagtagtg tgaagccatg     7680

ttttattgga cttaaagtta caatatatta caagcttgtg ttggaaggca gcaaaactaa     7740

ttcagacaac aacatgtctt cagttactgg atccctaatt ttcaggacaa aacctgtttt     7800

tcaataagat tgaacagtgc ctatttgtgg atttggagat gttactgtca agatgactaa     7860

tggagacata cgaccagctg tgtctgatgt cataaaacac gtgttcactg aaaggacaat     7920

aagactatat accttctcag gtccccttgc aattctaaaa ctctgtgatc atataaattg     7980

gaaggaaagg ggaggggata tggttaatct ttgcttaagc tgtaagaata aaaaagttat     8040

ctcctatact attaacttct gaaataagtt ctgagacgag acatctgaaa ataagcagct     8100

gcattatttg tatgtttctt cactgccaag atgtgttcaa gcctgctata cctgccattg     8160

tattggaagg cttaatgaat ttcatttatt ttctgcaaca acgattacag aatttattgc     8220

acaaaatgag acattttgag agtgatatta attacatgag ggacaatagg catgaactag     8280

gattgttcta agcaaatcgg aatcgggtca ccctgccacg ttcaggtgct tggaccttca     8340

ggaaaagatt gcccatcttg tcatttgacc aggcactgaa gtgacaagac catccttgag     8400

aagtcacatc caaagataaa attctgatcc atttctagtt ttagtgtttc gccactgaag     8460

acttaacata tgtcttttac actcaggttg caaaacacag gcccaagaca aacttaactt     8520

ctcccccaaa tcttccttcc gctggttttt ccatctcgta agtggtgcca ctatccatct     8580

gttaaattgt ttaggggaaa cctagaaaag cactacctta atcagtgtta tccttcttct     8640

taactgtgcg tcctaatttc tccacatctt tcttaagtgc agtgaccaaa ccggatgaga     8700

attctaacac gggcctgaca tcaaatggaa aggaaggata atgtccagga gttggaatgt     8760

tatccttgtt tttaattaag atgcaattca cataaattaa ctttttaagt gaacaattaa     8820

gtggtagtac atccacaatg gtgtacaacc accacttcta tctagctcca aaacattctc     8880

atcactccaa aagtaaagtc ccgttactct ccattttctc ctcccaccgc ccttgtccct     8940

ggcaaccacc aatctgcttc ctgtttcttt ggatttacat ccgggtattt catgtgagac     9000

tcatacactg tgtattactt ctttcgtcta gctttaatgt gttgttgagg ttgatccatt     9060

gtaacatgtt atcactactt cattcctttt tatagctaag tatacttttt atagtaagta     9120

tgccattgta gatatatacc acaagtttat cgattcatcc agttgagttg tttctactgt     9180

ttggctaatg ttcatagtgc tgttatgaat gttcgtgtac aagtatttga gtccgtgttt     9240

tcaattattt ggggtatatg cctgggagtg gagttgctgg gtcatgttga aatcgcacat     9300

ttaacttttt gaggaactgt caaactttcc ctcagcagct gtaccgtttt accttccacc     9360

attgatgtat gagggttcca atttctccac accttcacca acacttattt tgccatttta     9420

aaaattatag ccatcctcat gggtgtggtc tctcattgtg gttttgattt gcatttccct     9480

gattactaat gatgtggagc atcttttgtt gtctttggcc atctgcgtat cttctttgaa     9540

gaaatgtctg ttgaggtcct ttgttcattg aaattttgtt gttgggttct gagttcctta     9600

tatattctgg gtactaggcc cttataatat tttcgcctat aagtttttgc tttataatgt     9660

cctcattgtt ttcaaactta ctttatgtaa tatgtacact tctaaaaaaa agaaacatgg     9720

aaaagggcaa actgtaaaaa aaaaaaaaaa aa                                   9752


<210>  957
<211>  9916
<212>  DNA
<213>  homo sapiens

<400>  957
gggaggtggc tgccgggtgg gaggtgtgtg cgcgtgtgcc gcgccgtagg gagcggcggg       60

tcgcgccgcc ggctgtcagc tagctccgcg ccgccgcccg atggcgcgag gaggcgcgcg      120

ggcccagccc cggggggccg gccgcgggtg agcccctcgg cctgccgccc gcgagcatgt      180

cacctccagc cgccgccgcc gcagcctccg ccagccgcgc ccgcgccccc gcctcccgca      240

gccgcagccg ctgcctcggg cattggcccc cagacccccg cctctgatcc acgcccagac      300

cctagctcca gagggccatg gccggccagg gggactgctg cgtcaaggtg gccgtcagga      360

tccggcccca gctgtcgaag gagaagattg agggctgtca catctgtacc tctgttaccc      420

cgggagagcc ccaggtcctg ctggggaagg acaaggcctt cacctatgac tttgtcttcg      480

acctggacac ctggcaagaa cagatctatt ccacctgtgt gagcaagctc atcgagggct      540

gcttcgaggg ctataatgcc acggtgctgg cctatgggca gacgggggcc gggaagacgt      600

acaccatggg cactggcttt gacatggcaa cgtcggagga ggagcagggc atcatcccga      660

gggccatcgc acacctcttt gggggcattg ccgagcgcaa gcgccgggca caggagcagg      720

gcgtggctgg acctgagttc aaagtcagcg cccagtttct ggagctctac aacgaggaga      780

tccttgacct gtttgacagc acccgtgacc ctgacacccg ccaccgcagg tccaacatca      840

agatccacga ggacgcaaac ggtggcatct acaccactgg cgtcacttct cgcctcatcc      900

actcccagga ggagctgatc cagtgcctga agcagggggc cctgtcccgc accacagcca      960

gcacccagat gaacgtgcag agctcacgct cccacgccat cttcaccatc cacctgtgcc     1020

agatgcgcat gtgcacccag cccgacctgg tgaatgaggc ggtgactggg cttcctgatg     1080

gtacacctcc ctcgagtgag tatgagacac tcactgctaa gtttcacttt gtggacctgg     1140

ccggctcaga gcggctgaag cggacagggg ctactggcga gcgggccaag gagggcatct     1200

ccatcaactg tggcctgctg gccttgggca atgtgatcag cgccttaggg gaccagagca     1260

agaaggtggt gcacgttccc tacagggact ccaagctcac tcggctcctc caggattcgc     1320

tggggggcaa cagccagacc atcatgatcg cctgtgtgag cccctcagac cgagatttca     1380

tggagaccct caacacactc aaatatgcca atcgggcccg caacatcaag aacaaggtgg     1440

tagtgaacca ggacaagacc agccagcaaa tcagtgcact gcgggctgag attgctcggc     1500

tgcagatgga gctgatggag tataaggcgg gcaagcgagt gataggagag gatggcgctg     1560

agggctatag tgatctgttc cgagagaatg ccatgctaca gaaggagaat ggggccctgc     1620

ggctgcgggt gaaagccatg caggaggcca tcgatgccat caacaaccgc gtcacccagc     1680

tcatgagcca ggaggccaac ctgctgctag ccaaggccgg cgatggcaat gaggccattg     1740

gtgcgctgat ccagaactac atccgggaga tcgaggagct acggactaag cttctagaga     1800

gtgaagccat gaacgagtcc ctgcgccgca gcctctcacg ggcctcggct aggagcccct     1860

actccctggg tgcttctcca gccgccccgg ccttcggggg cagccctgcc agctccatgg     1920

aggatgcctc ggaggtgatc cgcagggcca agcaggacct ggagcggcta aagaagaagg     1980

aggtcaggca gcggaggaag agccccgaga aggaagcctt caaaaagagg gcaaaactcc     2040

aacaggagaa cagcgaggag acggatgaga acgaggcgga ggaggaggag gaagagcgag     2100

acgagagtgg ctgtgaggag gaggaagggc gcgaggatga agatgaggac tcgggcagtg     2160

aagagagcct ggtggactca gactcagacc ccgaggagaa ggaggtgaac ttccaggcgg     2220

acctggccga cctgacttgt gagatcgaaa tcaagcagaa gctgatcgac gagctggaga     2280

acagccagcg gcggttgcag acgctcaagc accagtatga ggaaaagctg attctgctgc     2340

agaacaagat ccgagacaca cagctggagc gcgaccgtgt gctgcagaac ctcagcacca     2400

tggagtgcta tactgaggag aaggccaaca agatcaaggc agactatgag aagaggctgc     2460

gggagatgaa ccgggacctg cagaagctgc aggccgccca gaaagagcac gcccggctgc     2520

ttaagaacca gtcgcgctac gagagggagc tgaagaagct acaggccgag gtggctgaga     2580

tgaagaaggc caaggtggcc ctgatgaagc agatgcgtga ggagcaacag cggcggcggc     2640

tagtggagac caagaggaac cgggagatcg cacagctcaa gaaggagcag cggcgacagg     2700

agtttcagat ccgagctctg gagtcccaga agcggcagca ggagatggtc ctgaggagga     2760

agacccagga ggtttctgca ctgaggcgcc tggccaagcc catgtctgag cgggtggcag     2820

ggcgtgcagg actaaagcca cccatgctgg actctggggc tgaggtgtcg gccagcacta     2880

cctcatctga ggctgaatca ggggcccgct ctgtctccag catcgtgcgc cagtggaacc     2940

gcaaaatcaa ccacttcttg ggggaccatc ctgcgcccac tgtcaatggc acccgtcctg     3000

cccgaaagaa gttccagaag aagggggcca gccagagctt cagtaaggcg gcaaggctca     3060

agtggcagtc cctggagcga cggatcattg acatcgtcat gcagagaatg accattgtca     3120

acctggaggc tgacatggag cggctcatca agaaaaggga ggagctgttc ctcctgcagg     3180

aggcactgcg gaggaagcgg gagcggctgc aggctgagag ccccgaggaa gagaaggggc     3240

tgcaggagct ggctgaggag atcgaggtgc tggcagccaa cattgactac atcaatgacg     3300

gcatcaccga ctgccaggcc accatcgtgc agctggagga gaccaaggag gagctggact     3360

ccacagacac atccgtggtc atcagctcct gctccctggc tgaagcccgc ctcctgctag     3420

acaacttcct caaggcatcc attgacaagg ggctgcaagt ggcacaaaag gaagcccaga     3480

tccggctgtt ggagggccga ctgaggcaga cggatatggc aggctcctcc cagaaccatc     3540

tgctcctgga cgccctgcgt gagaaggctg aagctcaccc cgagctgcag gccctcatct     3600

acaatgtgca gcaggagaat ggctacgcca gcacagatga ggagatctca gagttctctg     3660

agggcagctt ctcccagtca ttcaccatga aaggctccac cagccatgac gatttcaagt     3720

tcaagagcga gcccaaactg tctgcccaaa tgaaagctgt gtcggctgag tgcctgggcc     3780

ccccactgga tatctccacc aagaacatca ccaagtccct ggcctccctc gttgagatca     3840

aagaggacgg agtgggcttc tctgtccgag acccctatta ccgggacagg gtctcgcgca     3900

ccgtcagtct gcctacccgg ggcagcactt tccctaggca atctcgagcc acagagacgt     3960

ccccgctgac gagaaggaag tcctacgacc gagggcagcc cattaggtcc acagatgtgg     4020

gattcacacc cccatcatcc cctcccactc ggccccgcaa tgaccgcaat gtcttctctc     4080

gtctcaccag taatcagagc caggggtcag cgctggacaa gggcatcatc tccccggttg     4140

gaggagccaa gggtgcacgg acggccccac tgcagtgtgt ctccatggcc gaaggccaca     4200

ccaagcccat cctctgcctg gatgccacag atgagttgct attcacaggg tccaaagacc     4260

gaagctgcaa gatgtggaac ttggttacgg gacaggagat cgcagctcta aagggccacc     4320

ccaacaacgt ggtctccatc aagtactgca gccactcggg gcttgtgttc tccgtgtcca     4380

cctcctacat caaggtgtgg gacatccggg actcagccaa gtgcattcgg actctcacgt     4440

cctcgggcca ggtgatctca ggggatgcct gtgccgccac atccacccgt gccatcacca     4500

gtgctcaggg cgagcatcag atcaaccaga tcgccctcag cccttcgggc accatgctgt     4560

acgccgcctc gggcaatgcc gtccgcatct gggagcttag caggttccag cctgtcggca     4620

agctgactgg ccacatcggc cctgtgatgt gcctgacggt cacccagacg gccagccagc     4680

atgacctcgt ggtgactggc tccaaggacc actacgttaa gatgttcgag ctgggcgagt     4740

gtgtgacggg caccatcggc cccactcaca acttcgagcc cccgcactac gatggcatcg     4800

agtgtctcgc catccaggga gacatcctgt tcagtggctc ccgagataac ggcatcaaga     4860

agtgggacct agaccagcag gagctcatcc agcaaatccc caatgcgcac aaggactggg     4920

tgtgcgccct ggccttcatc ccgggccgcc ccatgctgct cagcgcctgc cgtgcgggtg     4980

tcatcaaggt ctggaacgtg gacaacttca cacccatcgg tgagatcaag ggccacgaca     5040

gtcccatcaa tgccatctgc accaatgcca agcatatctt cacagcctcc agtgactgcc     5100

gggtaaagtt gtggaattac gtccctggac tcaccccctg ccttcctcgc cgagtcctgg     5160

ccataaaggg ccgcgccacc accctgccct gaccctcccc aactctccct gtctcctctt     5220

tcattcttcc cctctttcct tttccctctc tttccccact tcgatctgag ctgcttctta     5280

acggtatgag attattttac tccttcttct tcctttccct tcctgtcctg cctggcctag     5340

agaggtgccc tgcctgtccc tcctgcaccc accgtccttt tccaagcatg aacagtggga     5400

caggccccag gagatgggtg ccagggagca gaagggggag ccttcaggcc tggacaaaac     5460

gaaacacccc cccaaaaaaa gaaaacccat gacaaagctc ccctgggggc ctctgagtgc     5520

acaggcctct ccatctgccc agcaccccac cacctgcagt ccacctcccc gtaagccatg     5580

cttgcctccc agccccaacc acatttgggg agtttgggga atccagttca tcctctactt     5640

ttgggggcag ccagccaagc ccactgcaag agctgaccgg cacccctcca ctttgtcctc     5700

caccccagtg acctgacggt gaagttctgg agtgtccggc ggttacccca cagcggccca     5760

ccctaggagt gaggtcagag ggatgccccc ggaccctcga ccccagcagc ctggacacca     5820

tggaagggaa gctgtgaccc ggccgatggg gccagctgct ctggggacag agggcgtggc     5880

cccctctcct gccctcctcc ctctcccttg gccttcccac aggacactgt tccctcatcc     5940

ctcccctgcc tctcaggagc ctctgggtga gagagaggct ggggaggaaa ttaagctgtg     6000

aagccaaagg gcattatccc ttcttgttcc cctcctggca gtcgtggcca cattgtctcc     6060

tgctgaaccg gctctgcccc tttctcaggc ctttggccca gtggtggagc cctgtgggga     6120

ggtgcagcag cctggcccca tcccaccctt ccgaggagct ggcctccccg cttctcccag     6180

cccagcctct agagccactg cacctgcctc tgagcccaaa aagataagtc ctcaggtagc     6240

taaggaaacc aggtgtgggc ggctgggcct tgcagctaac ccttaaccct ctggcaaccc     6300

gcagatagcc ccaactggcc ccaacagttc cctggggtcc cttttggatg gggccaaggt     6360

ggagctgcta gaaagattcc tttggggaga tggtcagaaa tacttcagtt atttattatt     6420

ttgttatttt tattttttgc tgttgcctcc tggaaacgga cttgaagttt cttcccctat     6480

attctttccc tcagctcttg ggggccagaa atcccaaagg gagtccgctg ccccggccct     6540

ccagggccgc ctcctctgtt tgctttgcag aggagggaac tgctccttcg actctgcagc     6600

tcaggcctgt ccccgacaca gcccccaggg agtcttctag ctacccctgg cctctaggcc     6660

gcctgacgct cagtgccttc ctccgttccg gggcctggca cccgtgccgg gcagccttac     6720

accagccatg cccgcggcac cacatgtgtc ttctcactcg cgaggtcttg tgcccagcgc     6780

ccccgggaag gcgggggcgc tcaccccaca gcccaggccc cggggttctg ccccacagtc     6840

ctgcgtgggc cacgtaggaa gcagcatggg ggctgtgtct gctgggaggt ggcttggatg     6900

gggaggacag cccggcaccc tgacccccgc ccctccccag ccctgcagtc ccccactggg     6960

ccggggagtc tctccagctt ctctctctct ggttattcag gagacacatt ttcggcctta     7020

aaactggcat ggagcgcagg ccctcccttg cagaaaatta tcaaggaaga gggagttggc     7080

agagtttctc tgccccgggg ctggggacgc ggagctccgg ggaaattgtt aaatcagtgt     7140

tctggcgccc cctgttgggg gaactctgga attacaggag tgggccttgg gggggactga     7200

gctccatccc tctcccccgc cccaccccca cccaaagttg cccaccctgt ttttccgttg     7260

catcgctggt cttgtgcttc ccgcttcagt ctgggagcca agagccagcc ccacctccct     7320

tcagaggacg cagtgacttt tggactttcc agaggtggtt ctgtgtttct gcccttggct     7380

cctctccgtc ttgggctggg gcacttggag ccctctccat gtggcgccca gtgttggggg     7440

gaggcaggct ccagtggagg ctgagtgagg cctggtccct tccccgtgcc ctcctcggag     7500

ctgccacaga ggctaagacg gctgtcctgc tggtgctggc cctgctggat gtggtattga     7560

agtctggggc agctgatagc aggaaggaga cccccttgga tgctggtctc ctgggacctg     7620

aacagtctgt cagcaatggc tggaaatcct tcttcctctg gccaccccgg gggtgccggg     7680

caaccccctt agctctaaga tgtggccaca aatctcttcc cactcctccc cgccaacctg     7740

aacagaaagt tttgaccttg caacctgtaa gaaagaatcc gtccgcatga ctgtttacaa     7800

gcgatagaaa cacgtaagac tctgtcccct tgagctccca cccccgggcc ggggatgccc     7860

cacctggggt gactgcactg tagctgcaag gcgtgttctt gcacgaagtg tgatcttatg     7920

gccctgcgag aggtgctcat catcatgccc attttctgct gtttctgatg ggtcagctac     7980

ctcacggcgg ggccagctct gctgtcctgg caagtgtcat tgactctcta aacttgaagt     8040

ccttcaggag ccctgagccc aacatccatg agacaccccg agttgtgctt catgagagtt     8100

ggattctctg cccactcttt cagggatgtc caaggtccat gttagggggc aggcccccag     8160

ctccactcac tgcacaagca ccctaaatgt tggaagcaca aaatggttgt gatttgagca     8220

caatggcagg gtcccgcagg cagacttgac aggcccaggc ccgggaggat ccccccacgt     8280

tggctctgtc caaagtgaga ttgggggtgc ctgtgtctgg gacagggggc tgcccttgct     8340

cagaccaggc cttggctcat ggcttgtcct aattctggga ctcgtcatct tacttcttgc     8400

ccttctgtgc ccatcttaag actggaggct gagccttgtc aggcccagcc acatctttac     8460

gccatgggac caggagtaaa gcgctctcta aaccccgcac cccaaatctc taaacgcctg     8520

agttcaggct gagtcctagc cctagtgagc ctgaagagct tggactgatt cccagtctcc     8580

tgggtcaagc cccactttgt gctttcgaag cttatgagcg ggttccctgg atagaaggag     8640

tcttccatcc ccactgccct tgggcctctt cagcatagtc ctgtgccagg gccctgtcct     8700

cactatcagt cagttcagta tttgctttca cgtgagtggc ggactcttct gaagcagcca     8760

gaactctcaa aggcagcgca tggagttgcc ttgcgagatt tccaaggaag gaggaaagat     8820

taacaggcgg agcctggcac acccaagcct ttgaggtggt cagagtgcca ccttcagccc     8880

cttgggaagg gacagcggtg ggtctgggag tggcctcacc ctggattcag cctaggaatc     8940

tcttcaccct cagctgtcca gccctgctgc ctgtctgggg atgtgtggcc tgggcagagg     9000

gcagtttaaa gcacaaaacc acatggggaa aacacaaggt tgcggggact ttctcatgtg     9060

cctgatgtgg tggagggaga caccagcagg tggctgcagt gacgttaggg aacataacac     9120

ttctttgccc tgctagctct cagctctggg gggcatcccc cgatgtggtc tgggctggga     9180

gcaggcatat cccctggttg ttgcctgtgc ctggtctgtt caccatcgtg tttgtgtggg     9240

cagagcctgc cctgcaggag cagtgacttt cttcccactg tgtgtcccgg acctgtggta     9300

tgtgtccctt tgccatccca aacaggcaac tgcttgctgc tctccttgct tggcatagcc     9360

tcctggtcag tggccaatgc cccacaggcc ttcctgggcc tggccctcct ctcctgactc     9420

ccagatcctt ccctgccctc ttgtgtgcaa ggacagattt tgcagggaaa gttctgtttc     9480

ttctttgata cctttgttct gtcccctgcc ccatccccag cactcatgat cttgaagccc     9540

ctatcacact ctagttcagt cctgtgaacc atgtcctgag ggccttgcag ggaagtagga     9600

aatagaaact cctccacaaa gagccgagga tcagagaaga cccctgagat gaatcagggc     9660

cctgccctgc ccaccaactc ttttctagca atcatgtcct gcccaggctg caggcttcat     9720

taggctcctg ctgtcctcca tgatgtgact agcacaaggt gtatatatgt tttgtacctc     9780

tgccgatggc tgtacatagt gtatgaaagt tatttaagcc ccatgttgta catttctgtt     9840

cctagattgg atgtgtgtgt tctaagaagt tgtcataaat aaaacctgaa tgaccaatgt     9900

caaaaaaaaa aaaaaa                                                     9916


<210>  958
<211>  4000
<212>  DNA
<213>  homo sapiens

<400>  958
gcgggcggtc ccggcgaggc gggaggggcc ggggcagagg gagggtcttc gcctccccac       60

ccccagcccc gtttccggag cccgcgatgg agctttgtga agatgcaggc gttggggctg      120

ctcggcgatg atgacatcat cgtgtcacac acaggagccg gctgccgggg ggtttaagag      180

aagagccttt cggaccacac cggcgctcac gctcataccc gcacgccccg ggcagagccg      240

cgcacgccgg ccacactcgg gcgcgcgccg gccacactcg cgcgcacaca tacgcggcgc      300

tcgccccccg gcccccggct cgggccgcga gtcgcagctc cctgccgccg ctcccgccgc      360

cacggatgcc cgcagctgct cccctctgca gtgcagcaac cccggccgcc ggccggctcg      420

ccccggctcc cggctgcagg aatcgcgcca ggacgctggc cccgctcgcg gctagcttgc      480

acgccagggc acagcgagga tgggagggtc gcagtccctg cagccagccc cagccagcga      540

cctgaacctg gaggcttccg aggcaatgag ttccgattct gaagaggcat ttgagacccc      600

ggagtcaacg acccctgtca aagctccgcc agctccaccc ccaccacccc ccgaagtcat      660

cccagaaccc gaggtcagca cacagccacc cccggaagaa ccaggatgtg gttctgagac      720

agtccctgtc cctgatggcc cacggagcga ctcggtggaa ggaagtccct tccgtccccc      780

gtcacactcc ttctctgccg tcttcgatga agacaagccg atagccagca gtgggactta      840

caacttggac tttgacaaca ttgagcttgt ggataccttt cagaccttgg agcctcgtgc      900

ctcagacgct aagaatcagg agggcaaagt gaacacacgg aggaagtcca cggattccgt      960

ccccatctct aagtctacac tgtcccggtc gctcagcctg caagccagtg actttgatgg     1020

tgcttcttcc tcaggcaatc ccgaggccgt ggcccttgcc ccagatgcat atagcacggg     1080

ttccagcagt gcttctagta cccttaagcg aactaaaaaa ccgaggccgc cttccttaaa     1140

aaagaaacag accaccaaga aacccacaga gaccccccca gtgaaggaga cgcaacagga     1200

gccagatgaa gagagccttg tccccagtgg ggagaatcta gcatctgaga cgaaaacgga     1260

atctgccaag acggaaggtc ctagcccagc cttattggag gagacgcccc ttgagcccgc     1320

tgtggggccc aaagctgcct gccctctgga ctcagagagt gcagaagggg ttgtcccccc     1380

ggcttctgga ggtggcagag tgcagaactc accccctgtc gggaggaaaa cgctgcctct     1440

taccacggcc ccggaggcag gggaggtaac cccatcggat agcggggggc aagaggactc     1500

tccagccaaa gggctctccg taaggctgga gtttgactat tctgaggaca agagtagttg     1560

ggacaaccag caggaaaacc cccctcctac caaaaagata ggcaaaaagc cagttgccaa     1620

aatgcccctg aggaggccaa agatgaaaaa gacacccgag aaacttgaca acactcctgc     1680

ctcacctccc agatcccctg ctgaacccaa tgacatcccc attgctaaag gtacttacac     1740

ctttgatatt gacaagtggg atgaccccaa ttttaaccct ttttcttcca cctcaaaaat     1800

gcaggagtct cccaaactgc cccaacaatc atacaacttt gacccagaca cctgtgatga     1860

gtccgttgac ccctttaaga catcctctaa gacccccagc tcaccttcta aatccccagc     1920

ctcctttgag atcccagcca gtgctatgga agccaatgga gtggacgggg atgggctaaa     1980

caagcccgcc aagaagaaga agacgcccct aaagactgac acatttaggg tgaaaaagtc     2040

gccaaaacgg tctcctctct ctgatccacc ttcccaggac cccaccccag ctgctacacc     2100

agaaacacca ccagtgatct ctgcggtggt ccacgccaca gatgaggaaa agctggcggt     2160

caccaaccag aagtggacgt gcatgacagt ggacctagag gctgacaaac aggactaccc     2220

gcagccctcg gacctgtcca cctttgtaaa cgagaccaaa ttcagttcac ccactgagga     2280

gttggattac agaaactcct atgaaattga atatatggag aaaattggct cctccttacc     2340

tcaggacgac gatgccccga agaagcaggc cttgtacctt atgtttgaca cttctcagga     2400

gagccctgtc aagtcatctc ccgtccgcat gtcagagtcc ccgacgccgt gttcagggtc     2460

aagttttgaa gagactgaag cccttgtgaa cactgctgcg aaaaaccagc atcctgtccc     2520

acgaggactg gcccctaacc aagagtcaca cttgcaggtg ccagagaaat cctcccagaa     2580

ggagctggag gccatgggct tgggcacccc ttcagaagcg attgaaatta cagctcccga     2640

gggctccttt gcctctgctg acgccctcct cagcaggcta gctcaccccg tctctctctg     2700

tggtgcactt gactatctgg agcccgactt agcagaaaag aaccccccac tattcgctca     2760

gaaactccag agagaggctg ctcacccaac agacgtctcc atctccaaaa cagccttgta     2820

ctcccgcatc gggaccgctg aggtggagaa acctgcaggc cttctgttcc agcagcccga     2880

cctggactct gccctccaga tcgccagagc agagatcata accaaggaga gagaggtctc     2940

agaatggaaa gataaatatg aagaaagcag gcgggaagtg atggaaatga ggaaaatagt     3000

ggccgagtat gagaagacca tcgctcagat gatagaggac gaacagagag agaagtcagt     3060

ctcccaccag acggtgcagc agctggttct ggagaaggag caagccctgg ccgacctgaa     3120

ctccgtggag aagtctctgg ccgacctctt cagaagatat gagaagatga aggaggtcct     3180

agaaggcttc cgcaagaatg aagaggtgtt gaagagatgt gcgcaggagt acctgtcccg     3240

ggtgaagaag gaggagcaga ggtaccaggc cctgaaggtg cacgcggagg agaaactgga     3300

cagggccaat gctgagattg ctcaggttcg aggcaaggcc cagcaggagc aagccgccca     3360

ccaggccagc ctgcggaagg agcagctgcg agtggacgcc ctggaaagga cgctggagca     3420

gaagaataaa gaaatagaag aactcaccaa gatttgtgac gaactgattg ccaaaatggg     3480

gaaaagctaa ctctgaaccg aatgttttgg acttaactgt tgcgtgcaat atgaccgtcg     3540

gcacactgct gttcctccag ttccatggac aggttctgtt ttcacttttt cgtatgcact     3600

actgtatttc ctttctaaat aaaattgatt tgattgtatg cagtactaag gagactatca     3660

gaatttcttg ctattggttt gcattttcct agtataattc atagcaagtt gacctcagag     3720

ttcctgtatc agggagattg tctgattctc taataaaaga cacattgctg accttggcct     3780

tgccctttgt acacaagttc ccagggtgag cagcttttgg atttaatatg aacatgtaca     3840

gcgtgcatag ggactcttgc cttaaggagt gtaaacttga tctgcatttg ctgatttgtt     3900

tttaaaaaaa caagaaatgc atgtttcaaa taaaattctc tattgtaaat aaaatttttt     3960

ctttggatct tggcaataaa aaaaaaaaaa aaaaaaaaaa                           4000


<210>  959
<211>  2853
<212>  DNA
<213>  homo sapiens

<400>  959
gtgggcaaag gtacttaaag ccctgaccgt cgttctccgt cctcctctgg gtaccaactc       60

tattgcgcag ctcgctgccg tgcgtttaac ccaggcgagg aggaggagga gaaaattccc      120

ccagattcgg gcagacacct ccggcccaca cagccgttca ccccccgtct tttcagtcct      180

ggaaaaggaa ttcgggcttt cattgtctaa cgtcgacagt ctatatttct gctcttcagt      240

ctgtccttag gatgaagctc taactgaact gaagtaagga gaaacagcct tgaatctttg      300

gagggtctgt cttccttttg ggctctgtgc aactgcagct acagtggaaa aaagcaaact      360

gctcttgatc ccaggccctg cctaagcctc agcagaactt gtaagcctaa actgaagagc      420

ctcacccgga cgagcaggca tcccttaacc ttaagcaatc cagttccacg ccctggatca      480

gtgaataacc ccagctgcac catgagccgc gttcgggatg ctggctgtgt agcggcgggg      540

atagtgatag gggctggtgc ctggtactgt gtctacaaat acaccagggg gagagaccag      600

accaagaaga gaatggccaa gcccaaaaac cgggctgtgg ctgggactgg agccagggct      660

agagctgggc taagagccgg attcacaatc gaccttgggt caggattcag tcccccaacc      720

ccagtccgtg ctgaagcaga ggacagggcc caggatgaag cctctgctct ggacacagtt      780

ggagctgagg cagtggcccc agctgcatcc agcgctgagg ctcagagtgg ggcaggcagt      840

caggcccaag aggcagatgg agccggggtt gggcctaagg ccgaatcagt agttggggct      900

gcaatggctt ctgcaatagc accacctccc ggggtgacag aggcccttgg ggctgcagaa      960

gcccctgcaa tggcaggggc tcccaaagtg gcagaagctc ccagagaagc ggagacttcc     1020

agggcagcgg tgcctcctgg gacagtggtg cctaccgaag cggcagcacc cactgaggtg     1080

accgagggtc ctggggtagc agcacctacc aaggtagctg aagctcccgg ggtggcatcg     1140

cctaccgagg cagctgaggc tcctgtgccg gcaacgccta ctggggctgc agcacctact     1200

ggggctgcag agtctcctgg aacttctggt tcccctagaa cagcggtggt tcctggaaca     1260

tcagctgcca agaaagcaac ccctggggct cacactgggg ctataccgaa agccacatca     1320

gcgactggag cggtacccaa aggtggaggc aagggtgtaa ccaggtcccg gaatgggggc     1380

aagggcaagg gcaagaaaag caaagttgaa gtagacgaac tggggatggg cttccgtcct     1440

ggagatgggg ctgcagcagc tgctgcagcc tctgctaatg gcggacaggc tttcctggca     1500

gaggtccctg attctgagga aggggagtcc gggtggactg acacagagtc agattcagac     1560

tctgagcccg agacccagcg cagagggagg ggaagaagac ccgttgccat gcagaagcgc     1620

ccctttcctt atgaaattga tgagattctg ggtgtccgcg atctcaggaa ggtccttgcc     1680

ttgcttcaga aatctgatga tcctttcatc caacaggtag ctttgctcac tctgagcaac     1740

aatgccaatt attcatgcaa tcaagagaca atccgcaaat tgggaggcct cccaattatt     1800

gcaaacatga tcaacaaaac tgatccacac attaaggaaa aagccttaat ggccatgaat     1860

aacctgagtg agaattatga aaatcagggc cggcttcagg tgtacatgaa taaagtgatg     1920

gatgatatca tggcctctaa cctgaactca gcagttcaag tagttggact aaaatttcta     1980

acaaacatga ctattactaa tgactaccaa cacctgcttg tcaattccat tgcaaacttt     2040

ttccgtttgc tatctcaggg aggtggaaaa atcaaggttg agattttgaa aatcctttcg     2100

aattttgctg aaaatccaga tatgttgaag aaacttctca gtacccaagt gccagcatca     2160

tttagttccc tctataattc ttacgtggaa tcagaaatcc ttattaatgc ccttactcta     2220

tttgagatta tctatgacaa tctcagagca gaagtgttta actatagaga attcaataaa     2280

ggttcccttt tttacttatg cactacatct ggagtgtgtg ttaagaaaat tagagcctta     2340

gcaaatcacc atgacctctt agtgaaagtg aaagttataa aactagtgaa caaattctga     2400

ttggttatgt accgtcaaaa gacttgaaga aatttcatga ttttgcagtg tggaagcgtt     2460

gaaaattgaa agttactgct tttccacttg ctcatatagt aaagggatcc tttcagctgc     2520

cagtgttgaa taatgtatca tccagagtga tgttatctgt gacagtcacc agctttaagc     2580

tgaaccattt tatgaatacc aaataaatag acctcttgta ctgaaaacat atttgtgact     2640

ttaatcgtgc tgcttggata gaaatatttt tactggttct tctgaattga cagtaaacct     2700

gtccattatg aatggcctac tgttctatta tttgttttga cttgaattta tccaccaaag     2760

acttcatttg tgtatcatca ataaagttgt atgtttcaac tgacaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa                                  2853


<210>  960
<211>  11241
<212>  DNA
<213>  homo sapiens

<400>  960
tccgcccgga tagccggcgg cggcggcggc ggcggcggcg gcggcggccg ggagaggccc       60

ctccttcacg ccctgcttct ctccctcgct cgcagtcgag ccgagccggc ggacccgcct      120

gggctccgac cctgcccagg ccatggccgg caacgtgaag aagagctctg gggccggggg      180

cggcagcggc tccgggggct cgggttcggg tggcctgatt gggctcatga aggacgcctt      240

ccagccgcac caccaccacc accaccacct cagcccccac ccgccgggga cggtggacaa      300

gaagatggtg gagaagtgct ggaagctcat ggacaaggtg gtgcggttgt gtcagaaccc      360

aaagctggcg ctaaagaata gcccacctta tatcttagac ctgctaccag atacctacca      420

gcatctccgt actatcttgt caagatatga ggggaagatg gagacacttg gagaaaatga      480

gtattttagg gtgtttatgg agaatttgat gaagaaaact aagcaaacca taagcctctt      540

caaggaggga aaagaaagaa tgtatgagga gaattctcag cctaggcgaa acctaaccaa      600

actgtccctc atcttcagcc acatgctggc agaactaaaa ggaatctttc caagtggact      660

ctttcaggga gacacatttc ggattactaa agcagatgct gcggaatttt ggagaaaagc      720

ttttggggaa aagacaatag tcccttggaa gagctttcga caggctctac atgaagtgca      780

tcccatcagt tctgggctgg aggccatggc tctgaaatcc actattgatc tgacctgcaa      840

tgattatatt tcggtttttg aatttgacat ctttacccga ctctttcagc cctggtcctc      900

tttgctcagg aattggaaca gccttgctgt aactcatcct ggctacatgg cttttttgac      960

gtatgacgaa gtgaaagctc ggctccagaa attcattcac aaacctggca gttatatctt     1020

ccggctgagc tgtactcgtc tgggtcagtg ggctattggg tatgttactg ctgatgggaa     1080

cattctccag acaatccctc acaataaacc tctcttccaa gcactgattg atggcttcag     1140

ggaaggcttc tatttgtttc ctgatggacg aaatcagaat cctgatctga ctggcttatg     1200

tgaaccaact ccccaagacc atatcaaagt gacccaggaa caatatgaat tatactgtga     1260

gatgggctcc acattccaac tatgtaaaat atgtgctgaa aatgataagg atgtaaagat     1320

tgagccctgt ggacacctca tgtgcacatc ctgtcttaca tcctggcagg aatcagaagg     1380

tcagggctgt cctttctgcc gatgtgaaat taaaggtact gaacccatcg tggtagatcc     1440

gtttgatcct agagggagtg gcagcctgtt gaggcaagga gcagagggag ctccctcccc     1500

aaattatgat gatgatgatg atgaacgagc tgatgatact ctcttcatga tgaaggaatt     1560

ggctggtgcc aaggtggaac ggccgccttc tccattctcc atggccccac aagcttccct     1620

tcccccggtg ccaccacgac ttgaccttct gccgcagcga gtatgtgttc cctcaagtgc     1680

ttctgctctt ggaactgctt ctaaggctgc ttctggctcc cttcataaag acaaaccatt     1740

gccagtacct cccacacttc gagatcttcc accaccaccg cctccagacc ggccatattc     1800

tgttggagca gaatcccgac ctcaaagacg ccccttgcct tgtacaccag gcgactgtcc     1860

ctccagagac aaactgcccc ctgtcccctc tagccgcctt ggagactcat ggctgccccg     1920

gccaatcccc aaagtaccag tatctgcccc aagttccagt gatccctgga caggaagaga     1980

attaaccaac cggcactcac ttccattttc attgccctca caaatggagc ccagaccaga     2040

tgtgcctagg ctcggaagca cgttcagtct ggatacctcc atgagtatga atagcagccc     2100

attagtaggt ccagagtgtg accaccccaa aatcaaacct tcctcatctg ccaatgccat     2160

ttattctctg gctgccagac ctcttcctgt gccaaaactg ccacctgggg agcaatgtga     2220

gggtgaagag gacacagagt acatgactcc ctcttccagg cctctacggc ctttggatac     2280

atcccagagt tcacgagcat gtgattgcga ccagcagatt gatagctgta cgtatgaagc     2340

aatgtataat attcagtccc aggcgccatc tatcaccgag agcagcacct ttggtgaagg     2400

gaatttggcc gcagcccatg ccaacactgg tcccgaggag tcagaaaatg aggatgatgg     2460

gtatgatgtc ccaaagccac ctgtgccggc cgtgctggcc cgccgaactc tctcagatat     2520

ctctaatgcc agctcctcct ttggctggtt gtctctggat ggtgatccta caacaaatgt     2580

cactgaaggt tcccaagttc ccgagaggcc tccaaaacca ttcccgcgga gaatcaactc     2640

tgaacggaaa gctggcagct gtcagcaagg tagtggtcct gccgcctctg ctgccaccgc     2700

ctcacctcag ctctccagtg agatcgagaa cctcatgagt caggggtact cctaccagga     2760

catccagaaa gctttggtca ttgcccagaa caacatcgag atggccaaaa acatcctccg     2820

ggaatttgtt tccatttctt ctcctgccca tgtagctacc tagcacacca tctccctgct     2880

gcaggtttag aggaccagtg agttgggagt tattactcaa gtggcaccta gaagggcagg     2940

agttcctttg gtgacttcac agtgaagtct tgccctctct gtgggatatc acatcagtgg     3000

ttccaagatt tcaaagtggt gaaatgaaaa tggagcagct agtatgtttt attattttat     3060

gggtcttgag tgcatttgaa ggtgtccttc agttcccacg tagagagagt gtggattata     3120

ttacatgata acctacctgg ggaacagtcc agaaagctat agaacaagta ttttgctgga     3180

aatcctaatt gaggacttaa gacttcctgg gttaaggatg tggccgtgtg tgtgtgtgtc     3240

tgcctgtggt tgtatgtgtc cttgtgatta taagattaac ctgctgtgtg tgttaattcc     3300

aggcagggaa ttagcacaaa aggtttagga aggaatcttt ttttaaagac ttccatctac     3360

tgtggtatta tacccaagcc tagtgtgtat tacaacttca acactcccct ttggcttata     3420

ttaccatgtg catagctaaa gtcttctatt tttagaacac cttctgtctg ttctttcccc     3480

atcaactcct tcctcatcct tcttggtgtt ctgtcatggg ccatgggctt gctatggcca     3540

gccttactga ggccaagcag cttatgggat gttctttatt gtgtgtgatg gtattggttt     3600

gtttggtaga taagtgggag gaaaagtact gttgctacac tattataggc atgtttgata     3660

ctagcagcta acactggtca ctccaaagca ctgtttctat aggaacattg aagctattaa     3720

gatgttttga ttatcctaat tacataatga ccgatttgag atagaggcct ttaaatacat     3780

tccatgccct ccccagaaaa tagtctgtgg gagtcagttg ccttggtgcc aggtatgtgt     3840

tctgatgtag gtcatgagtc tttctactta atgggaaggg aagaacattt gtttccagga     3900

tgactttctg gccagaatac cggaaagctt ttaggaagct tcgttcacat gctatttaaa     3960

tgcacaaaat agacagtaag gatttatctg ttcagttttt cttcccagtg aattaatttc     4020

agcttatatg ggtgtcttca tttgaacatg aggaatatta ggttatattt tcagcagtgg     4080

ttttttcctt tgccctttaa ggagtgggga taatgtccac ggtggcccag cctcttgctg     4140

atggcacctt ccctgcattg ctgcctcccg atgatgtggt tcttttcttg tgcctgtggc     4200

tttgggaatg taacatctct ttcctccttt ccttcccttt tcctcttcac ctgaggtcct     4260

aaatactctc tgtaattact gtgttcttca cggtaattag acatcattca gtgaataaat     4320

tactgtagtc aaagacagta tgggctggca gtttgtgtaa ttgcaagttc ataaagagaa     4380

ttgagggtcc agttgggaga actattagtc agttctttta tatgctgata aatgatccct     4440

cgagttcagt tagtattctg tccagagtgt ttagctcact ttcttagcag tgtgtaagct     4500

ttctccatgt cagaagcaag cctgctcttt gataaatctg tcttcctgaa aatctaaatc     4560

atgcttttgt ctttagatct acacagaaat gaccctcctt ggatcagttt tctttccagt     4620

ctaatcatct ttggaactaa aacttgttct aactcgtctc ttggcattca gctactccta     4680

gatcttttgg ttttatcccc tggcctcaga gccatttata ttcccagagt aggcagtaca     4740

ggatctcgtg ttgatttgct gtggttaccc agtgtcttct ctacatggca taaagcggca     4800

aagcccacca ttaggtgagg cggtcccgag ttgaggtaga gtggggcaga ggaagatggc     4860

agtgaatatc aaacagtaga ccgccatcaa cttctaacag ccagtacaca cactgtttca     4920

ttttgaggta acgttcagtt ttgcattttg tttaaatatt gaaggcctag acaaagaact     4980

agaaaaaaaa aagcagtttc caggcccatc catattgtaa tttttcttta tctgcagata     5040

ttgcctgtag tctaaagatc tctttggaag acaaagcatt ggctatatat cttttgcctt     5100

ttccatgcat ctaaatcttc tctggagatt atctccctac tgtgtaggtt aagggcagtc     5160

tcgacttttc cttttttgag tcctgtgtgg ctctttgaat cagcgtgaaa ctgaggctcc     5220

agctccctgt gttgtgtgtg tgtgccatcc atgggcttgg gtgtcagttt gtcacaggta     5280

tctgccagca ttcaaggttt tggatcattt catgaggatc tttcctttga ctgggtgctg     5340

tgaggacaca cctgggtctg tgcctgagat tgccaggcaa gattaaggaa agttttcatg     5400

tggcttttgt tttgaggtta ttctcaaaac cttaatttct tatattttct gttgactaag     5460

gcaccagtaa cccattcttc accctccatt tgtatggcaa tttaaaagtc tttggctttg     5520

ctctgaattt aattaaaact gccttttatg aacagacttc gagttttgcc attttgggca     5580

agcccttccg cttgtccctt cctagtggct aataaagtaa aaaaacccac actactttgt     5640

tctctttttc tcatattcat tgggctgttg tattcagcca gtctcatgct ttccctgggt     5700

cttcacggat tgctttccaa gctgccttgt tgcggggttg ctgcagagca gcaactggac     5760

ctttccagct gtcgccatgt tccttccact aaagtagagg gttcttaaaa tggaaaaacc     5820

tgtgggctct tcatatacct ccctttagtt aagtaataga ccaggcagct tctcatctca     5880

gcatttacct gttaatattt ttgtgaatag tgctctctac ctgtgggtgg ccgttctctt     5940

ccacttgctc gtctcccccc agccccattc tgcataatct accattcttc tcctctcttt     6000

ctcttcttat acagaccctc attactgggg cccaagatgt gggatactac tgttagtatt     6060

atttaactat tttgtagatt taaaagattt ctggttaagg gaggtggggg tcactgttca     6120

tcactcttaa aatatgtgtt ttctctatag aaaagtaaaa tgtgtttatg gtcccaaaca     6180

gtcaactcac aaatttttat aacaaaattt ccttgtaaaa actagggacc atctatatat     6240

tccctttaag atctagttct ttttgtaggt gttcagcaat ggtgataaag cagaatattc     6300

tcctacctca cgtcattaaa gtcagaagat tatagacctt ctcaaactat aagtccctct     6360

tcttgccgtt ggcctttctg actctggaat gaccactgtt cattgaaaaa tagttttctg     6420

actattggtc tggctctaac agtttgtttg ttcatccagc aaatgtttat gagtgatgac     6480

catgtgccag aaatgtcagg tatgtgtcct tcccttggcg ccacatagta gtttactaat     6540

gtttggggga ttgtacttgg actgtcatag cctctgcgtt tgaccttaaa atagctcttc     6600

ccagtaagat tgtgcaattt ttattcacag ctcttccatg tagacttacc tttcctcata     6660

gagctatcct ggttaataac aggccaagat tctcccatta tcccctgttg tctcctgtag     6720

ctttgataat gcctgggaga ttccttggtg taagtgtcat ggataccgac tgtttttatg     6780

ttggaatttg ttccaacata attagaatct gtttggtgag ttgaaaggta agttggctca     6840

gagttgcaca gtagggcatt aaatgtttaa gcaaagcatc tgcccacact cccctttcca     6900

atctagtgcc ttccttgaac tttttcctga gctgctacgt ccctaatccc ccttgttggg     6960

aggattttcg tatcaccctt atgggacctg tcaccatgtc ctgtactatt tggaattggt     7020

tttccagtct ttcaacaacc gttgtggcta actatgtttt agaagggctg gaggtgtggg     7080

ccctgtcttc gggtctcagg acccaaagat cctttagtca gttgttgggt cttccaagag     7140

ccagacatta atacagattg aactccatca gtcccctaat tgtcagcctt tacctccctc     7200

ccagagcaag gagtttaggg attctaaagc ttagtgtcca cacatcattc taccagacct     7260

tagagcttta gaagctcaat ctaaaatact gtaactcagc ataaactatt actatcactc     7320

ctttgaactc agtctccatg agcagtgttt tgttggaaat acatagaacg gcttaatgcc     7380

tagagggtgg tggatagtga aggacggtca aggttatatt tttgactgct tagggattct     7440

ttggatccaa gaaacagaaa tgttcaagcg gaataaagga gggagtggag ttgtggtaag     7500

gatgcagggt atttcgcaga acccaggacg ggaagtgcct ttggttcttg ggtggagctg     7560

gaactgcaga gctttgcacc tagtcctttc tcccgcttca cagtctgctt atggtatatg     7620

tggcccccaa ataggcactc tagtcctcaa gtctacacca ccttccaact ctggggatca     7680

ccatgaacaa attctcaatt tcccatactt aatttttttt ttttttgaga tggagtctcg     7740

ctgtgtcgcc caggctggag tgcagtggtg cagtctcaac tcaccacaac ctctgcctcc     7800

caggttcaag cagttctctg cctcaacctc ccgagtagct gggattacag gcgcctgcca     7860

ccatgcccag ctaatgttca tatttttagt agagacaggg tttcaccgtc ttggctaggc     7920

tggtcttgaa ctcctgaccc tcatgatcca cccacctcgg cctcccaaag tgctaagatt     7980

acaggcgtga gccaccgcgc ccggcccata cttcgtattc ttaaaaaaaa ctacactcag     8040

cccagcacat tgatcaagta tctatctctg agcagttggc cttgccaggg agagcagaga     8100

tgtggcaggc tccttcagct ggagacaggg agcttctcag agaagtgagc agagactcca     8160

cagacaccct aaaaaggctt ctactcaaga agtaaagcca ctactcctgc ctttttgctt     8220

agtggacagg aaggcacagg agtttgtctg ggacatcata gaaattctta ggtttaactt     8280

aattctggtc attgtcttct ttatttcctg tttttcttcc ctttgtcagt cttcgcatcc     8340

aagatttctt ccctccctct tgtgggccag cctgtcctgt tccagagcta gcctgttcct     8400

gggtagcctt ccttagcctc cattcagcct caggtctttt gccttcttcc gtgtttattt     8460

agagagcaga atctaataac gggttccact gtagccacta tccatggact tctgggtcct     8520

cttcaggttt gagtgcttga aaatgttcat tctctgggct tgtggcctgt ctcctccact     8580

ctcctcctca ccctctcgct ccttcctgtg tgagggccgc tctgcagtaa tgttctcagg     8640

caagccttcc taggcacctc agaaactact ttgccagagc cagtaagaat atataatatt     8700

ggagcagttg ccaggataga aattaaatat agattccagt ttaggataga gtttttaccg     8760

agagctcttt agacagtata cctgtgtctt ctctggcaat tgctttcatt ttagtcctat     8820

ataaaagctt tccttttctg ttttttttta aaactatgct tttgcttgcc taaatctttt     8880

gatcttatat ttctctcatc tcagagcctg tcctgagttg taaggtattt catactgcct     8940

tacttaaaag ttttttaaac tactagagtc atttgataca cacagaagtt acctaataat     9000

ccaaagatgt ccatcaaggg aggaagggtg ggtcatcaga ctttgccttt gatgttgtag     9060

actaggctcc tgagttaagc agcagaggga cagcagtgcc atgtgccttc actgtgtccc     9120

aggaaatctg ggttggttcc agtgggaaat accagtattt cttggttctg gaaagtagca     9180

aaagagtagg agatggggaa atagggatgg ggagagcaag ccccgcatgt ccatggcgag     9240

tcaggtgggg agcacgggtg gaagggccgg ctgttgacag acagactaag ctgtgtggtg     9300

ctcttgccgc cccttcctgg gtacagagct tgagaaaaat gcagccgacc actccctgtg     9360

tttgtacaga gcaaagccca aaagccaacc tcagatctcc tgatttggca gctgaagaaa     9420

tcagcagagt cctgattgcc tgattcagtc ccaaaaatga atgtcaggcc ccgccccctc     9480

cccaccaaca ttgcctctcc tacattctcc ttctgcccct aaatcagaca ggaggccaga     9540

gaggagtatt gctcaatgcg tgctatgtgc aactcctcag gccttgtgcc acctccatgc     9600

tgagccctga agcagggtgt cctgggtgcc tgtgtgtcag ctccctcctc tctacctacc     9660

tctgaccttc ttgtgggtga gggtggccat gcttatggcc atcttaaaac tggagaggca     9720

gagaactact tatgagtctg tagaccacgt gttgtcttcc atggcctgtt tctcctgctg     9780

tctgggtgag tgagcctgca acgcaatgcc catgagagta aatgcctcct gacctaccct     9840

gctcagcact gttctagtgt cttggccttg aaagaaaagc ctgacttcct gctgacacat     9900

gtggtagggg catggcagct atgaggcacc tcctacgtct gttttctggc tgtggtgact     9960

tgggattttt aaccttatat atctttttcc tttactcaaa acaaaacaat ttttagcaca    10020

ctgaaaaaaa aaaaaagcca aatgttttgt gcctttctaa ggcagcactg tatcccaggc    10080

tgcattttag gacttaatat ggaaatacca gagtctgagc tcctctacct tgagtttcat    10140

tagtccttag tgtctaggag acaggaaaga atgctctctg tgactggaga ggtgacatgc    10200

aggtgcagtg tgtctggagt ccctttcccc tgctgtgaga cttcagtgga ggagagaagc    10260

attgtaccct gggatcattt ggttggttcc aatcacaagc ttagttatca ggttgcatgc    10320

cttgtctcct gcaaaagaca gaatgtttca caattcccag gtaaactctg gaccattcca    10380

agtgtcctag ccttctgatg acattaatta cctagttgtg tcgaggagta taggatggac    10440

tctcctgaga aggggaggtt ggtggctttg tcttttcttt ttgctggatc ctgaactggt    10500

ctagacctcc tgcccccacc ccccagcccc catcagatgt ggctggcctt tcatttgaag    10560

gcttcagact taaagcatta agcagctagt gccctctgca gggcctggtt tccccaggga    10620

agggcagcaa ggaacatggg accagaagcc tgtcctcagt aatgtgacta tagtgagctt    10680

tagcaaaagt ttttctatat aatgacatct tacttatctt ttaccctttc ctcagttttc    10740

ccctgccttt aactaataaa gaattgggag acagaaattt taaagtcctc cttattcaag    10800

attttgaaat tcttagcctg ggagtgctgg agagaacctg atgctttctc cagaatgaag    10860

agtcccaatt tgtatatcag tgttaagaag aaaacaaaac aaacacatag gtgagatttt    10920

cgtggactat tttaaaaatg tgtcattaat ataaaaaatt tatattagca gtatttaatc    10980

attctcacct gtaaagaata agaaaaacag aaggtaaata ttcttacaga gaatagcaga    11040

gctttaagat tcattttcat tttaagtcca ttttattttg ccagtgtatt aatgtttaga    11100

agtctgtttt actaatgtta tttattaatt ttttttcatt tccatacaca gttagttaac    11160

taaagagctt tttcaagcac ccatgtctgt aaaaaaatat ttttaaataa agtttctttt    11220

gttgtagcag aaaaaaaaaa a                                              11241


<210>  961
<211>  11241
<212>  DNA
<213>  homo sapiens

<400>  961
tccgcccgga tagccggcgg cggcggcggc ggcggcggcg gcggcggccg ggagaggccc       60

ctccttcacg ccctgcttct ctccctcgct cgcagtcgag ccgagccggc ggacccgcct      120

gggctccgac cctgcccagg ccatggccgg caacgtgaag aagagctctg gggccggggg      180

cggcagcggc tccgggggct cgggttcggg tggcctgatt gggctcatga aggacgcctt      240

ccagccgcac caccaccacc accaccacct cagcccccac ccgccgggga cggtggacaa      300

gaagatggtg gagaagtgct ggaagctcat ggacaaggtg gtgcggttgt gtcagaaccc      360

aaagctggcg ctaaagaata gcccacctta tatcttagac ctgctaccag atacctacca      420

gcatctccgt actatcttgt caagatatga ggggaagatg gagacacttg gagaaaatga      480

gtattttagg gtgtttatgg agaatttgat gaagaaaact aagcaaacca taagcctctt      540

caaggaggga aaagaaagaa tgtatgagga gaattctcag cctaggcgaa acctaaccaa      600

actgtccctc atcttcagcc acatgctggc agaactaaaa ggaatctttc caagtggact      660

ctttcaggga gacacatttc ggattactaa agcagatgct gcggaatttt ggagaaaagc      720

ttttggggaa aagacaatag tcccttggaa gagctttcga caggctctac atgaagtgca      780

tcccatcagt tctgggctgg aggccatggc tctgaaatcc actattgatc tgacctgcaa      840

tgattatatt tcggtttttg aatttgacat ctttacccga ctctttcagc cctggtcctc      900

tttgctcagg aattggaaca gccttgctgt aactcatcct ggctacatgg cttttttgac      960

gtatgacgaa gtgaaagctc ggctccagaa attcattcac aaacctggca gttatatctt     1020

ccggctgagc tgtactcgtc tgggtcagtg ggctattggg tatgttactg ctgatgggaa     1080

cattctccag acaatccctc acaataaacc tctcttccaa gcactgattg atggcttcag     1140

ggaaggcttc tatttgtttc ctgatggacg aaatcagaat cctgatctga ctggcttatg     1200

tgaaccaact ccccaagacc atatcaaagt gacccaggaa caatatgaat tatactgtga     1260

gatgggctcc acattccaac tatgtaaaat atgtgctgaa aatgataagg atgtaaagat     1320

tgagccctgt ggacacctca tgtgcacatc ctgtcttaca tcctggcagg aatcagaagg     1380

tcagggctgt cctttctgcc gatgtgaaat taaaggtact gaacccatcg tggtagatcc     1440

gtttgatcct agagggagtg gcagcctgtt gaggcaagga gcagagggag ctccctcccc     1500

aaattatgat gatgatgatg atgaacgagc tgatgatact ctcttcatga tgaaggaatt     1560

ggctggtgcc aaggtggaac ggccgccttc tccattctcc atggccccac aagcttccct     1620

tcccccggtg ccaccacgac ttgaccttct gccgcagcga gtatgtgttc cctcaagtgc     1680

ttctgctctt ggaactgctt ctaaggctgc ttctggctcc cttcataaag acaaaccatt     1740

gccagtacct cccacacttc gagatcttcc accaccaccg cctccagacc ggccatattc     1800

tgttggagca gaatcccgac ctcaaagacg ccccttgcct tgtacaccag gcgactgtcc     1860

ctccagagac aaactgcccc ctgtcccctc tagccgcctt ggagactcat ggctgccccg     1920

gccaatcccc aaagtaccag tatctgcccc aagttccagt gatccctgga caggaagaga     1980

attaaccaac cggcactcac ttccattttc attgccctca caaatggagc ccagaccaga     2040

tgtgcctagg ctcggaagca cgttcagtct ggatacctcc atgagtatga atagcagccc     2100

attagtaggt ccagagtgtg accaccccaa aatcaaacct tcctcatctg ccaatgccat     2160

ttattctctg gctgccagac ctcttcctgt gccaaaactg ccacctgggg agcaatgtga     2220

gggtgaagag gacacagagt acatgactcc ctcttccagg cctctacggc ctttggatac     2280

atcccagagt tcacgagcat gtgattgcga ccagcagatt gatagctgta cgtatgaagc     2340

aatgtataat attcagtccc aggcgccatc tatcaccgag agcagcacct ttggtgaagg     2400

gaatttggcc gcagcccatg ccaacactgg tcccgaggag tcagaaaatg aggatgatgg     2460

gtatgatgtc ccaaagccac ctgtgccggc cgtgctggcc cgccgaactc tctcagatat     2520

ctctaatgcc agctcctcct ttggctggtt gtctctggat ggtgatccta caacaaatgt     2580

cactgaaggt tcccaagttc ccgagaggcc tccaaaacca ttcccgcgga gaatcaactc     2640

tgaacggaaa gctggcagct gtcagcaagg tagtggtcct gccgcctctg ctgccaccgc     2700

ctcacctcag ctctccagtg agatcgagaa cctcatgagt caggggtact cctaccagga     2760

catccagaaa gctttggtca ttgcccagaa caacatcgag atggccaaaa acatcctccg     2820

ggaatttgtt tccatttctt ctcctgccca tgtagctacc tagcacacca tctccctgct     2880

gcaggtttag aggaccagtg agttgggagt tattactcaa gtggcaccta gaagggcagg     2940

agttcctttg gtgacttcac agtgaagtct tgccctctct gtgggatatc acatcagtgg     3000

ttccaagatt tcaaagtggt gaaatgaaaa tggagcagct agtatgtttt attattttat     3060

gggtcttgag tgcatttgaa ggtgtccttc agttcccacg tagagagagt gtggattata     3120

ttacatgata acctacctgg ggaacagtcc agaaagctat agaacaagta ttttgctgga     3180

aatcctaatt gaggacttaa gacttcctgg gttaaggatg tggccgtgtg tgtgtgtgtc     3240

tgcctgtggt tgtatgtgtc cttgtgatta taagattaac ctgctgtgtg tgttaattcc     3300

aggcagggaa ttagcacaaa aggtttagga aggaatcttt ttttaaagac ttccatctac     3360

tgtggtatta tacccaagcc tagtgtgtat tacaacttca acactcccct ttggcttata     3420

ttaccatgtg catagctaaa gtcttctatt tttagaacac cttctgtctg ttctttcccc     3480

atcaactcct tcctcatcct tcttggtgtt ctgtcatggg ccatgggctt gctatggcca     3540

gccttactga ggccaagcag cttatgggat gttctttatt gtgtgtgatg gtattggttt     3600

gtttggtaga taagtgggag gaaaagtact gttgctacac tattataggc atgtttgata     3660

ctagcagcta acactggtca ctccaaagca ctgtttctat aggaacattg aagctattaa     3720

gatgttttga ttatcctaat tacataatga ccgatttgag atagaggcct ttaaatacat     3780

tccatgccct ccccagaaaa tagtctgtgg gagtcagttg ccttggtgcc aggtatgtgt     3840

tctgatgtag gtcatgagtc tttctactta atgggaaggg aagaacattt gtttccagga     3900

tgactttctg gccagaatac cggaaagctt ttaggaagct tcgttcacat gctatttaaa     3960

tgcacaaaat agacagtaag gatttatctg ttcagttttt cttcccagtg aattaatttc     4020

agcttatatg ggtgtcttca tttgaacatg aggaatatta ggttatattt tcagcagtgg     4080

ttttttcctt tgccctttaa ggagtgggga taatgtccac ggtggcccag cctcttgctg     4140

atggcacctt ccctgcattg ctgcctcccg atgatgtggt tcttttcttg tgcctgtggc     4200

tttgggaatg taacatctct ttcctccttt ccttcccttt tcctcttcac ctgaggtcct     4260

aaatactctc tgtaattact gtgttcttca cggtaattag acatcattca gtgaataaat     4320

tactgtagtc aaagacagta tgggctggca gtttgtgtaa ttgcaagttc ataaagagaa     4380

ttgagggtcc agttgggaga actattagtc agttctttta tatgctgata aatgatccct     4440

cgagttcagt tagtattctg tccagagtgt ttagctcact ttcttagcag tgtgtaagct     4500

ttctccatgt cagaagcaag cctgctcttt gataaatctg tcttcctgaa aatctaaatc     4560

atgcttttgt ctttagatct acacagaaat gaccctcctt ggatcagttt tctttccagt     4620

ctaatcatct ttggaactaa aacttgttct aactcgtctc ttggcattca gctactccta     4680

gatcttttgg ttttatcccc tggcctcaga gccatttata ttcccagagt aggcagtaca     4740

ggatctcgtg ttgatttgct gtggttaccc agtgtcttct ctacatggca taaagcggca     4800

aagcccacca ttaggtgagg cggtcccgag ttgaggtaga gtggggcaga ggaagatggc     4860

agtgaatatc aaacagtaga ccgccatcaa cttctaacag ccagtacaca cactgtttca     4920

ttttgaggta acgttcagtt ttgcattttg tttaaatatt gaaggcctag acaaagaact     4980

agaaaaaaaa aagcagtttc caggcccatc catattgtaa tttttcttta tctgcagata     5040

ttgcctgtag tctaaagatc tctttggaag acaaagcatt ggctatatat cttttgcctt     5100

ttccatgcat ctaaatcttc tctggagatt atctccctac tgtgtaggtt aagggcagtc     5160

tcgacttttc cttttttgag tcctgtgtgg ctctttgaat cagcgtgaaa ctgaggctcc     5220

agctccctgt gttgtgtgtg tgtgccatcc atgggcttgg gtgtcagttt gtcacaggta     5280

tctgccagca ttcaaggttt tggatcattt catgaggatc tttcctttga ctgggtgctg     5340

tgaggacaca cctgggtctg tgcctgagat tgccaggcaa gattaaggaa agttttcatg     5400

tggcttttgt tttgaggtta ttctcaaaac cttaatttct tatattttct gttgactaag     5460

gcaccagtaa cccattcttc accctccatt tgtatggcaa tttaaaagtc tttggctttg     5520

ctctgaattt aattaaaact gccttttatg aacagacttc gagttttgcc attttgggca     5580

agcccttccg cttgtccctt cctagtggct aataaagtaa aaaaacccac actactttgt     5640

tctctttttc tcatattcat tgggctgttg tattcagcca gtctcatgct ttccctgggt     5700

cttcacggat tgctttccaa gctgccttgt tgcggggttg ctgcagagca gcaactggac     5760

ctttccagct gtcgccatgt tccttccact aaagtagagg gttcttaaaa tggaaaaacc     5820

tgtgggctct tcatatacct ccctttagtt aagtaataga ccaggcagct tctcatctca     5880

gcatttacct gttaatattt ttgtgaatag tgctctctac ctgtgggtgg ccgttctctt     5940

ccacttgctc gtctcccccc agccccattc tgcataatct accattcttc tcctctcttt     6000

ctcttcttat acagaccctc attactgggg cccaagatgt gggatactac tgttagtatt     6060

atttaactat tttgtagatt taaaagattt ctggttaagg gaggtggggg tcactgttca     6120

tcactcttaa aatatgtgtt ttctctatag aaaagtaaaa tgtgtttatg gtcccaaaca     6180

gtcaactcac aaatttttat aacaaaattt ccttgtaaaa actagggacc atctatatat     6240

tccctttaag atctagttct ttttgtaggt gttcagcaat ggtgataaag cagaatattc     6300

tcctacctca cgtcattaaa gtcagaagat tatagacctt ctcaaactat aagtccctct     6360

tcttgccgtt ggcctttctg actctggaat gaccactgtt cattgaaaaa tagttttctg     6420

actattggtc tggctctaac agtttgtttg ttcatccagc aaatgtttat gagtgatgac     6480

catgtgccag aaatgtcagg tatgtgtcct tcccttggcg ccacatagta gtttactaat     6540

gtttggggga ttgtacttgg actgtcatag cctctgcgtt tgaccttaaa atagctcttc     6600

ccagtaagat tgtgcaattt ttattcacag ctcttccatg tagacttacc tttcctcata     6660

gagctatcct ggttaataac aggccaagat tctcccatta tcccctgttg tctcctgtag     6720

ctttgataat gcctgggaga ttccttggtg taagtgtcat ggataccgac tgtttttatg     6780

ttggaatttg ttccaacata attagaatct gtttggtgag ttgaaaggta agttggctca     6840

gagttgcaca gtagggcatt aaatgtttaa gcaaagcatc tgcccacact cccctttcca     6900

atctagtgcc ttccttgaac tttttcctga gctgctacgt ccctaatccc ccttgttggg     6960

aggattttcg tatcaccctt atgggacctg tcaccatgtc ctgtactatt tggaattggt     7020

tttccagtct ttcaacaacc gttgtggcta actatgtttt agaagggctg gaggtgtggg     7080

ccctgtcttc gggtctcagg acccaaagat cctttagtca gttgttgggt cttccaagag     7140

ccagacatta atacagattg aactccatca gtcccctaat tgtcagcctt tacctccctc     7200

ccagagcaag gagtttaggg attctaaagc ttagtgtcca cacatcattc taccagacct     7260

tagagcttta gaagctcaat ctaaaatact gtaactcagc ataaactatt actatcactc     7320

ctttgaactc agtctccatg agcagtgttt tgttggaaat acatagaacg gcttaatgcc     7380

tagagggtgg tggatagtga aggacggtca aggttatatt tttgactgct tagggattct     7440

ttggatccaa gaaacagaaa tgttcaagcg gaataaagga gggagtggag ttgtggtaag     7500

gatgcagggt atttcgcaga acccaggacg ggaagtgcct ttggttcttg ggtggagctg     7560

gaactgcaga gctttgcacc tagtcctttc tcccgcttca cagtctgctt atggtatatg     7620

tggcccccaa ataggcactc tagtcctcaa gtctacacca ccttccaact ctggggatca     7680

ccatgaacaa attctcaatt tcccatactt aatttttttt ttttttgaga tggagtctcg     7740

ctgtgtcgcc caggctggag tgcagtggtg cagtctcaac tcaccacaac ctctgcctcc     7800

caggttcaag cagttctctg cctcaacctc ccgagtagct gggattacag gcgcctgcca     7860

ccatgcccag ctaatgttca tatttttagt agagacaggg tttcaccgtc ttggctaggc     7920

tggtcttgaa ctcctgaccc tcatgatcca cccacctcgg cctcccaaag tgctaagatt     7980

acaggcgtga gccaccgcgc ccggcccata cttcgtattc ttaaaaaaaa ctacactcag     8040

cccagcacat tgatcaagta tctatctctg agcagttggc cttgccaggg agagcagaga     8100

tgtggcaggc tccttcagct ggagacaggg agcttctcag agaagtgagc agagactcca     8160

cagacaccct aaaaaggctt ctactcaaga agtaaagcca ctactcctgc ctttttgctt     8220

agtggacagg aaggcacagg agtttgtctg ggacatcata gaaattctta ggtttaactt     8280

aattctggtc attgtcttct ttatttcctg tttttcttcc ctttgtcagt cttcgcatcc     8340

aagatttctt ccctccctct tgtgggccag cctgtcctgt tccagagcta gcctgttcct     8400

gggtagcctt ccttagcctc cattcagcct caggtctttt gccttcttcc gtgtttattt     8460

agagagcaga atctaataac gggttccact gtagccacta tccatggact tctgggtcct     8520

cttcaggttt gagtgcttga aaatgttcat tctctgggct tgtggcctgt ctcctccact     8580

ctcctcctca ccctctcgct ccttcctgtg tgagggccgc tctgcagtaa tgttctcagg     8640

caagccttcc taggcacctc agaaactact ttgccagagc cagtaagaat atataatatt     8700

ggagcagttg ccaggataga aattaaatat agattccagt ttaggataga gtttttaccg     8760

agagctcttt agacagtata cctgtgtctt ctctggcaat tgctttcatt ttagtcctat     8820

ataaaagctt tccttttctg ttttttttta aaactatgct tttgcttgcc taaatctttt     8880

gatcttatat ttctctcatc tcagagcctg tcctgagttg taaggtattt catactgcct     8940

tacttaaaag ttttttaaac tactagagtc atttgataca cacagaagtt acctaataat     9000

ccaaagatgt ccatcaaggg aggaagggtg ggtcatcaga ctttgccttt gatgttgtag     9060

actaggctcc tgagttaagc agcagaggga cagcagtgcc atgtgccttc actgtgtccc     9120

aggaaatctg ggttggttcc agtgggaaat accagtattt cttggttctg gaaagtagca     9180

aaagagtagg agatggggaa atagggatgg ggagagcaag ccccgcatgt ccatggcgag     9240

tcaggtgggg agcacgggtg gaagggccgg ctgttgacag acagactaag ctgtgtggtg     9300

ctcttgccgc cccttcctgg gtacagagct tgagaaaaat gcagccgacc actccctgtg     9360

tttgtacaga gcaaagccca aaagccaacc tcagatctcc tgatttggca gctgaagaaa     9420

tcagcagagt cctgattgcc tgattcagtc ccaaaaatga atgtcaggcc ccgccccctc     9480

cccaccaaca ttgcctctcc tacattctcc ttctgcccct aaatcagaca ggaggccaga     9540

gaggagtatt gctcaatgcg tgctatgtgc aactcctcag gccttgtgcc acctccatgc     9600

tgagccctga agcagggtgt cctgggtgcc tgtgtgtcag ctccctcctc tctacctacc     9660

tctgaccttc ttgtgggtga gggtggccat gcttatggcc atcttaaaac tggagaggca     9720

gagaactact tatgagtctg tagaccacgt gttgtcttcc atggcctgtt tctcctgctg     9780

tctgggtgag tgagcctgca acgcaatgcc catgagagta aatgcctcct gacctaccct     9840

gctcagcact gttctagtgt cttggccttg aaagaaaagc ctgacttcct gctgacacat     9900

gtggtagggg catggcagct atgaggcacc tcctacgtct gttttctggc tgtggtgact     9960

tgggattttt aaccttatat atctttttcc tttactcaaa acaaaacaat ttttagcaca    10020

ctgaaaaaaa aaaaaagcca aatgttttgt gcctttctaa ggcagcactg tatcccaggc    10080

tgcattttag gacttaatat ggaaatacca gagtctgagc tcctctacct tgagtttcat    10140

tagtccttag tgtctaggag acaggaaaga atgctctctg tgactggaga ggtgacatgc    10200

aggtgcagtg tgtctggagt ccctttcccc tgctgtgaga cttcagtgga ggagagaagc    10260

attgtaccct gggatcattt ggttggttcc aatcacaagc ttagttatca ggttgcatgc    10320

cttgtctcct gcaaaagaca gaatgtttca caattcccag gtaaactctg gaccattcca    10380

agtgtcctag ccttctgatg acattaatta cctagttgtg tcgaggagta taggatggac    10440

tctcctgaga aggggaggtt ggtggctttg tcttttcttt ttgctggatc ctgaactggt    10500

ctagacctcc tgcccccacc ccccagcccc catcagatgt ggctggcctt tcatttgaag    10560

gcttcagact taaagcatta agcagctagt gccctctgca gggcctggtt tccccaggga    10620

agggcagcaa ggaacatggg accagaagcc tgtcctcagt aatgtgacta tagtgagctt    10680

tagcaaaagt ttttctatat aatgacatct tacttatctt ttaccctttc ctcagttttc    10740

ccctgccttt aactaataaa gaattgggag acagaaattt taaagtcctc cttattcaag    10800

attttgaaat tcttagcctg ggagtgctgg agagaacctg atgctttctc cagaatgaag    10860

agtcccaatt tgtatatcag tgttaagaag aaaacaaaac aaacacatag gtgagatttt    10920

cgtggactat tttaaaaatg tgtcattaat ataaaaaatt tatattagca gtatttaatc    10980

attctcacct gtaaagaata agaaaaacag aaggtaaata ttcttacaga gaatagcaga    11040

gctttaagat tcattttcat tttaagtcca ttttattttg ccagtgtatt aatgtttaga    11100

agtctgtttt actaatgtta tttattaatt ttttttcatt tccatacaca gttagttaac    11160

taaagagctt tttcaagcac ccatgtctgt aaaaaaatat ttttaaataa agtttctttt    11220

gttgtagcag aaaaaaaaaa a                                              11241


<210>  962
<211>  3543
<212>  DNA
<213>  homo sapiens

<400>  962
gccaagaagc ttgagagaag aaaaatttca gaaaaattgt ctcaatttga ctagaatatc       60

aatgaaccag gaaaactgaa gcaccttccc taaagaaaac ttgggtatac aattactcca      120

cagacagagc tgagggtttt ttacccaaat cagtcactgg attttgctgc ctgatacgtg      180

aatcttcttg gaatttttct catgtggatc taaggggaat gctttattat ggctgctgtt      240

gtccaacaga acgacctagt atttgaattt gctagtaacg tcatggagga tgaacgacag      300

cttggtgatc cagctatttt tcctgccgta attgtggaac atgttcctgg tgctgatatt      360

ctcaatagtt atgccggtct agcctgtgtg gaagagccca atgacatgat tactgagagt      420

tcactggatg ttgctgaaga agaaatcata gacgatgatg atgatgacat cacccttaca      480

gttgaagctt cttgtcatga cggggatgaa acaattgaaa ctattgaggc tgctgaggca      540

ctcctcaata tggattcccc tggccctatg ctggatgaaa aacgaataaa tgggattcct      600

gaagtgatgg aaacacagca ggtgcaagaa aaatatgcag actcaccggg agcctcatca      660

ccagaacagc ctaagaggaa aaaaggaaga aaaactaaac caccacgacc agattcccca      720

gccactacgc caaatatatc tgtgaagaag aaaaacaaag atggaaaggg aaacacaatt      780

tatctttggg agtttttact ggcactgctc caggacaagg ctacttgtcc taaatacatc      840

aagtggaccc agcgagagaa aggcattttt aaattggtgg attctaaagc agtgtccagg      900

ttgtggggga agcacaaaaa caaacctgat atgaattatg agaccatggg aagagcactc      960

aggtactatt accaaagggg tattctggca aaagtggaag gtcagcgctt ggtgtatcag     1020

tttaaagaaa tgccaaaaga tcttatatat ataaatgatg aggatccaag ttccagcata     1080

gagtcttcag atccatcgct atcttcatca gccacttcaa ataggaatca aaccagccgg     1140

tcgagagtat cttcaagtcc aggggtaaaa ggaggagcca ctacagttct aaaaccaggg     1200

aattctaaag ctgcaaaacc caaagatcct gtggaagttg cacaaccatc agaagttttg     1260

aggacagtgc agcccacgca gtctccatat cctacccagc tcttccggac tgttcatgta     1320

gtacagccag tacaggctgt cccagaggga gaagcagcta gaaccagtac catgcaggat     1380

gaaacattaa attcttccgt tcagagtatt aggactatac aggctccaac ccaagttcca     1440

gtggttgtgt ctcctaggaa tcagcagttg catacagtaa cactccaaac agtgccactc     1500

acaacagtta tagccagcac agatccatca gcaggtactg gatctcagaa gtttatttta     1560

caagccattc catcatcaca gcccatgaca gtactgaaag aaaatgtcat gctgcagtca     1620

caaaaggcgg gctctcctcc ttcaattgtc ttgggccctg cccaggttca gcaggtcctt     1680

actagcaatg ttcagaccat ttgcaatgga accgtcagtg tggcttcctc tccatccttc     1740

agtgctactg cacctgtggt gaccttttct cctcgcagtt cacagctggt tgctcaccca     1800

cctggcactg taatcacttc agttatcaaa actcaagaaa caaaaactct tacacaggaa     1860

gtagagaaaa aggaatctga agatcatttg aaagagaaca ctgagaaaac ggagcagcag     1920

ccacagcctt atgtgatggt agtgtccagt tccaatggat ttacttctca ggtagctatg     1980

aaacaaaacg aactgctgga acccaactct ttttagttaa tataccaaag cttatgaata     2040

attgtttgtt aattgaacat tttcaattat atgcagactg actgattcta agataaattc     2100

taaggaggtt tctaattttg taattgttaa aaatagagtt aattttgact ttgttagatg     2160

agggaggaaa actcaactgt ttctctttgt tatctaaatg tttcagaatt caatcgtgaa     2220

ggaacaggca ttttacacta tgaagacatt cttttgagat ttttatttca gttgctatat     2280

cataagcatt tttaaagttt cttttctaat tttacattgt attagatttt ctgattcttt     2340

tgtaaataca gaacttaaat agaaggcaac aggaaattta tataggaact attttcattc     2400

cacttgtgta agttaagtct tgactctttc aaatgcaaaa aacctatttt atgctttgtt     2460

aaaattatgg tgtcacttag attgacttta gttgactgca ctatataata tagaactatg     2520

aatatgtaga ataacatgaa aaattggagg tgctggtggt atggctgacc ctgtttcaga     2580

agcaggatag tataaaagca tcagcctaag aatggcactc ccactaacta gctatgtaat     2640

cttgacctct ttgggcttta gttcctctca taaaaggaag agatgtattg gattagacta     2700

gatgatcacc actttctctt ctagttctaa tttttttaat tctaatacct atattttcaa     2760

gttatgtcaa ttaaatcatt atcaggttat ttcctaatgt aagaatagct aaaatgttgc     2820

agagaaataa gtgacccaac aaaatttatt catctgttat gggtaagatc tgccataaat     2880

tcttcctaaa taatttgttt actaactctt taggccactg tgctttgcgg tccattagta     2940

aacttgtgtt gctaagtgct aaacagaata ctgctatttt gagagagtca agactctttc     3000

ttaagggcca agaaagcaac ttgagccttg ggctaatctg gctgagtagt cagttataaa     3060

agcataattg ctttatattt tggatcattt tttactgggg gcggacttgg ggggggttgc     3120

atacaaagat aacatatata tccaactttc tgaaatgaaa tgtttttaga ttactttttc     3180

aactgtaaat aatgtacatt taatgtcaca agaaaaaaat gtcttctgca aattttctag     3240

tataacagaa atttttgtag atgaaaaaaa tcattatgtt tagaggtcta atgctatgtt     3300

ttcatattac agagtgaatt tgtatttaaa caaaaattta aattttggaa tcctctaaac     3360

atttttgtat ctttaattgg tttattatta aataaatcat ataaaaattc tcagtgtctg     3420

ttttcaggca aaagtttctt aaagaataag tgtgcagaga atattactag aacatcagca     3480

ttacttaatg tttataaata aatttcatta gtcagaattg caaaaaaaaa aaaaaaaaaa     3540

aaa                                                                   3543


<210>  963
<211>  3760
<212>  DNA
<213>  homo sapiens

<400>  963
agaaacactt ggtttcatgt atgactcata agctgaagca cagacaccac ttccccaatc       60

tacaggagcc attttaacag ctaaaacttg tcggattgct ttttattttc aagctcaaaa      120

gacgatagag aaagaatact tgaaggccaa gaagcttgag agaagaaaaa tttcagaaaa      180

attgtctcaa tttgactaga atatcaatga accaggaaaa ctgaagcacc ttccctaaag      240

aaaacttggg tatacaatta ctccacagac agagctgagg gttttttacc caaatcagtc      300

actggatttt gctgcctgat acgtgaatct tcttggaatt tttctcatgt ggatctaagg      360

ggaatgcttt attatggctg ctgttgtcca acagaacgac ctagtatttg aatttgctag      420

taacgtcatg gaggatgaac gacagcttgg tgatccagct atttttcctg ccgtaattgt      480

ggaacatgtt cctggtgctg atattctcaa tagttatgcc ggtctagcct gtgtggaaga      540

gcccaatgac atgattactg agagttcact ggatgttgct gaagaagaaa tcatagacga      600

tgatgatgat gacatcaccc ttacagttga agcttcttgt catgacgggg atgaaacaat      660

tgaaactatt gaggctgctg aggcactcct caatatggat tcccctggcc ctatgctgga      720

tgaaaaacga ataaataata atatatttag ttcacctgaa gatgacatgg ttgttgcccc      780

agtcacccat gtgtccgtca cattagatgg gattcctgaa gtgatggaaa cacagcaggt      840

gcaagaaaaa tatgcagact caccgggagc ctcatcacca gaacagccta agaggaaaaa      900

aggaagaaaa actaaaccac cacgaccaga ttccccagcc actacgccaa atatatctgt      960

gaagaagaaa aacaaagatg gaaagggaaa cacaatttat ctttgggagt ttttactggc     1020

actgctccag gacaaggcta cttgtcctaa atacatcaag tggacccagc gagagaaagg     1080

catttttaaa ttggtggatt ctaaagcagt gtccaggttg tgggggaagc acaaaaacaa     1140

acctgatatg aattatgaga ccatgggaag agcactcagg tactattacc aaaggggtat     1200

tctggcaaaa gtggaaggtc agcgcttggt gtatcagttt aaagaaatgc caaaagatct     1260

tatatatata aatgatgagg atccaagttc cagcatagag tcttcagatc catcgctatc     1320

ttcatcagcc acttcaaata ggaatcaaac cagccggtcg agagtatctt caagtccagg     1380

ggtaaaagga ggagccacta cagttctaaa accagggaat tctaaagctg caaaacccaa     1440

agatcctgtg gaagttgcac aaccatcaga agttttgagg acagtgcagc ccacgcagtc     1500

tccatatcct acccagctct tccggactgt tcatgtagta cagccagtac aggctgtccc     1560

agagggagaa gcagctagaa ccagtaccat gcaggatgaa acattaaatt cttccgttca     1620

gagtattagg actatacagg ctccaaccca agttccagtg gttgtgtctc ctaggaatca     1680

gcagttgcat acagtaacac tccaaacagt gccactcaca acagttatag ccagcacaga     1740

tccatcagca ggtactggat ctcagaagtt tattttacaa gccattccat catcacagcc     1800

catgacagta ctgaaagaaa atgtcatgct gcagtcacaa aaggcgggct ctcctccttc     1860

aattgtcttg ggccctgccc aggttcagca ggtccttact agcaatgttc agaccatttg     1920

caatggaacc gtcagtgtgg cttcctctcc atccttcagt gctactgcac ctgtggtgac     1980

cttttctcct cgcagttcac agctggttgc tcacccacct ggcactgtaa tcacttcagt     2040

tatcaaaact caagaaacaa aaactcttac acaggaagta gagaaaaagg aatctgaaga     2100

tcatttgaaa gagaacactg agaaaacgga gcagcagcca cagccttatg tgatggtagt     2160

gtccagttcc aatggattta cttctcaggt agctatgaaa caaaacgaac tgctggaacc     2220

caactctttt tagttaatat accaaagctt atgaataatt gtttgttaat tgaacatttt     2280

caattatatg cagactgact gattctaaga taaattctaa ggaggtttct aattttgtaa     2340

ttgttaaaaa tagagttaat tttgactttg ttagatgagg gaggaaaact caactgtttc     2400

tctttgttat ctaaatgttt cagaattcaa tcgtgaagga acaggcattt tacactatga     2460

agacattctt ttgagatttt tatttcagtt gctatatcat aagcattttt aaagtttctt     2520

ttctaatttt acattgtatt agattttctg attcttttgt aaatacagaa cttaaataga     2580

aggcaacagg aaatttatat aggaactatt ttcattccac ttgtgtaagt taagtcttga     2640

ctctttcaaa tgcaaaaaac ctattttatg ctttgttaaa attatggtgt cacttagatt     2700

gactttagtt gactgcacta tataatatag aactatgaat atgtagaata acatgaaaaa     2760

ttggaggtgc tggtggtatg gctgaccctg tttcagaagc aggatagtat aaaagcatca     2820

gcctaagaat ggcactccca ctaactagct atgtaatctt gacctctttg ggctttagtt     2880

cctctcataa aaggaagaga tgtattggat tagactagat gatcaccact ttctcttcta     2940

gttctaattt ttttaattct aatacctata ttttcaagtt atgtcaatta aatcattatc     3000

aggttatttc ctaatgtaag aatagctaaa atgttgcaga gaaataagtg acccaacaaa     3060

atttattcat ctgttatggg taagatctgc cataaattct tcctaaataa tttgtttact     3120

aactctttag gccactgtgc tttgcggtcc attagtaaac ttgtgttgct aagtgctaaa     3180

cagaatactg ctattttgag agagtcaaga ctctttctta agggccaaga aagcaacttg     3240

agccttgggc taatctggct gagtagtcag ttataaaagc ataattgctt tatattttgg     3300

atcatttttt actgggggcg gacttggggg gggttgcata caaagataac atatatatcc     3360

aactttctga aatgaaatgt ttttagatta ctttttcaac tgtaaataat gtacatttaa     3420

tgtcacaaga aaaaaatgtc ttctgcaaat tttctagtat aacagaaatt tttgtagatg     3480

aaaaaaatca ttatgtttag aggtctaatg ctatgttttc atattacaga gtgaatttgt     3540

atttaaacaa aaatttaaat tttggaatcc tctaaacatt tttgtatctt taattggttt     3600

attattaaat aaatcatata aaaattctca gtgtctgttt tcaggcaaaa gtttcttaaa     3660

gaataagtgt gcagagaata ttactagaac atcagcatta cttaatgttt ataaataaat     3720

ttcattagtc agaattgcaa aaaaaaaaaa aaaaaaaaaa                           3760


<210>  964
<211>  3760
<212>  DNA
<213>  homo sapiens

<400>  964
agaaacactt ggtttcatgt atgactcata agctgaagca cagacaccac ttccccaatc       60

tacaggagcc attttaacag ctaaaacttg tcggattgct ttttattttc aagctcaaaa      120

gacgatagag aaagaatact tgaaggccaa gaagcttgag agaagaaaaa tttcagaaaa      180

attgtctcaa tttgactaga atatcaatga accaggaaaa ctgaagcacc ttccctaaag      240

aaaacttggg tatacaatta ctccacagac agagctgagg gttttttacc caaatcagtc      300

actggatttt gctgcctgat acgtgaatct tcttggaatt tttctcatgt ggatctaagg      360

ggaatgcttt attatggctg ctgttgtcca acagaacgac ctagtatttg aatttgctag      420

taacgtcatg gaggatgaac gacagcttgg tgatccagct atttttcctg ccgtaattgt      480

ggaacatgtt cctggtgctg atattctcaa tagttatgcc ggtctagcct gtgtggaaga      540

gcccaatgac atgattactg agagttcact ggatgttgct gaagaagaaa tcatagacga      600

tgatgatgat gacatcaccc ttacagttga agcttcttgt catgacgggg atgaaacaat      660

tgaaactatt gaggctgctg aggcactcct caatatggat tcccctggcc ctatgctgga      720

tgaaaaacga ataaataata atatatttag ttcacctgaa gatgacatgg ttgttgcccc      780

agtcacccat gtgtccgtca cattagatgg gattcctgaa gtgatggaaa cacagcaggt      840

gcaagaaaaa tatgcagact caccgggagc ctcatcacca gaacagccta agaggaaaaa      900

aggaagaaaa actaaaccac cacgaccaga ttccccagcc actacgccaa atatatctgt      960

gaagaagaaa aacaaagatg gaaagggaaa cacaatttat ctttgggagt ttttactggc     1020

actgctccag gacaaggcta cttgtcctaa atacatcaag tggacccagc gagagaaagg     1080

catttttaaa ttggtggatt ctaaagcagt gtccaggttg tgggggaagc acaaaaacaa     1140

acctgatatg aattatgaga ccatgggaag agcactcagg tactattacc aaaggggtat     1200

tctggcaaaa gtggaaggtc agcgcttggt gtatcagttt aaagaaatgc caaaagatct     1260

tatatatata aatgatgagg atccaagttc cagcatagag tcttcagatc catcgctatc     1320

ttcatcagcc acttcaaata ggaatcaaac cagccggtcg agagtatctt caagtccagg     1380

ggtaaaagga ggagccacta cagttctaaa accagggaat tctaaagctg caaaacccaa     1440

agatcctgtg gaagttgcac aaccatcaga agttttgagg acagtgcagc ccacgcagtc     1500

tccatatcct acccagctct tccggactgt tcatgtagta cagccagtac aggctgtccc     1560

agagggagaa gcagctagaa ccagtaccat gcaggatgaa acattaaatt cttccgttca     1620

gagtattagg actatacagg ctccaaccca agttccagtg gttgtgtctc ctaggaatca     1680

gcagttgcat acagtaacac tccaaacagt gccactcaca acagttatag ccagcacaga     1740

tccatcagca ggtactggat ctcagaagtt tattttacaa gccattccat catcacagcc     1800

catgacagta ctgaaagaaa atgtcatgct gcagtcacaa aaggcgggct ctcctccttc     1860

aattgtcttg ggccctgccc aggttcagca ggtccttact agcaatgttc agaccatttg     1920

caatggaacc gtcagtgtgg cttcctctcc atccttcagt gctactgcac ctgtggtgac     1980

cttttctcct cgcagttcac agctggttgc tcacccacct ggcactgtaa tcacttcagt     2040

tatcaaaact caagaaacaa aaactcttac acaggaagta gagaaaaagg aatctgaaga     2100

tcatttgaaa gagaacactg agaaaacgga gcagcagcca cagccttatg tgatggtagt     2160

gtccagttcc aatggattta cttctcaggt agctatgaaa caaaacgaac tgctggaacc     2220

caactctttt tagttaatat accaaagctt atgaataatt gtttgttaat tgaacatttt     2280

caattatatg cagactgact gattctaaga taaattctaa ggaggtttct aattttgtaa     2340

ttgttaaaaa tagagttaat tttgactttg ttagatgagg gaggaaaact caactgtttc     2400

tctttgttat ctaaatgttt cagaattcaa tcgtgaagga acaggcattt tacactatga     2460

agacattctt ttgagatttt tatttcagtt gctatatcat aagcattttt aaagtttctt     2520

ttctaatttt acattgtatt agattttctg attcttttgt aaatacagaa cttaaataga     2580

aggcaacagg aaatttatat aggaactatt ttcattccac ttgtgtaagt taagtcttga     2640

ctctttcaaa tgcaaaaaac ctattttatg ctttgttaaa attatggtgt cacttagatt     2700

gactttagtt gactgcacta tataatatag aactatgaat atgtagaata acatgaaaaa     2760

ttggaggtgc tggtggtatg gctgaccctg tttcagaagc aggatagtat aaaagcatca     2820

gcctaagaat ggcactccca ctaactagct atgtaatctt gacctctttg ggctttagtt     2880

cctctcataa aaggaagaga tgtattggat tagactagat gatcaccact ttctcttcta     2940

gttctaattt ttttaattct aatacctata ttttcaagtt atgtcaatta aatcattatc     3000

aggttatttc ctaatgtaag aatagctaaa atgttgcaga gaaataagtg acccaacaaa     3060

atttattcat ctgttatggg taagatctgc cataaattct tcctaaataa tttgtttact     3120

aactctttag gccactgtgc tttgcggtcc attagtaaac ttgtgttgct aagtgctaaa     3180

cagaatactg ctattttgag agagtcaaga ctctttctta agggccaaga aagcaacttg     3240

agccttgggc taatctggct gagtagtcag ttataaaagc ataattgctt tatattttgg     3300

atcatttttt actgggggcg gacttggggg gggttgcata caaagataac atatatatcc     3360

aactttctga aatgaaatgt ttttagatta ctttttcaac tgtaaataat gtacatttaa     3420

tgtcacaaga aaaaaatgtc ttctgcaaat tttctagtat aacagaaatt tttgtagatg     3480

aaaaaaatca ttatgtttag aggtctaatg ctatgttttc atattacaga gtgaatttgt     3540

atttaaacaa aaatttaaat tttggaatcc tctaaacatt tttgtatctt taattggttt     3600

attattaaat aaatcatata aaaattctca gtgtctgttt tcaggcaaaa gtttcttaaa     3660

gaataagtgt gcagagaata ttactagaac atcagcatta cttaatgttt ataaataaat     3720

ttcattagtc agaattgcaa aaaaaaaaaa aaaaaaaaaa                           3760


<210>  965
<211>  3242
<212>  DNA
<213>  homo sapiens

<400>  965
gattttagct cttcccaagt tgtgaaaata gtgaaggatg cttagactac ttaacataca       60

aactgctttc tggttaatca tctttagaag actggatttc tggatatcta ctccactcca      120

tctctattga cttttaaaac atgataatgc aaacctataa cactggcaac catcagtgaa      180

cctttaattt cattgattaa tagcgtttga agcttcctca gggaataaca atgacatcag      240

cagtggttga cagtggaggt actattttgg agctttccag caatggagta gaaaatcaag      300

aggaaagtga aaaggtttct gaatatccag cagtgattgt ggagccagtt ccaagtgcca      360

gattagagca gggctatgca gcccaggttc tggtttatga tgatgagact tatatgatgc      420

aagatgtggc agaagaacaa gaagttgaga ccgagaatgt ggaaacagtg gaagcatcag      480

ttcacagcag taatgcacac tgtacagata agacaattga agctgctgaa gccctgcttc      540

atatggaatc tcctacctgc ttgagggatt caagaagtcc tgaattcatc catgctgcta      600

tgaggccaga tgtcattaca gaaactgtag tggaggtgtc aactgaagag tctgaaccca      660

tggatacctc tcctattcca acatcaccag atagccatga accaatgaaa aagaaaaaag      720

ttggccgtaa accaaagacc cagcaatcac caatttccaa tgggtctcct gagttaggta      780

taaagaagaa accaagagaa ggaaaaggaa acacaaccta tttgtgggag tttcttttag      840

atctacttca agataaaaat acttgtccca ggtatattaa atggactcag agagaaaaag      900

gcatattcaa gctggtggat tcaaaggctg tctctaagct ttggggaaag cataagaaca      960

aaccagacat gaactatgaa accatgggac gagctttgag atactactac caaaggggaa     1020

ttcttgcaaa ggttgaagga cagaggcttg tatatcagtt caaggatatg ccgaaaaaca     1080

tagtggtcat agatgatgac aaaagtgaaa cctgtaatga agatttagca ggaactactg     1140

atgaaaaatc attagaacga gtgtcactgt ctgcagaaag tctcctgaaa gcagcatcct     1200

ctgttcgcag tggaaaaaat tcatccccta taaactgctc cagagcagag aagggtgtag     1260

ctagagttgt gaatatcact tcccctgggc acgatgcttc atccaggtct cctactacca     1320

ctgcatctgt gtcagcaaca gcagctccaa ggacagttcg tgtggcaatg caggtacctg     1380

ttgtaatgac atcattgggt cagaaaattt caactgtggc agttcagtca gttaatgcag     1440

gtgcaccatt aataaccagc actagtccaa caacagcgac ctctccaaag gtagtcattc     1500

agacaatccc tactgtgatg ccagcttcta ctgaaaatgg agacaaaatc accatgcagc     1560

ctgccaaaat tattaccatc ccagctacac agcttgcaca gtgtcaactg cagacaaagt     1620

caaatctgac tggatcagga agcattaaca ttgttggaac cccattggct gtgagagcac     1680

ttacccctgt ttcaatagcc catggtacac ctgtaatgag actatcaatg cctactcagc     1740

aggcatctgg ccagactcct cctcgagtta tcagtgcagt cataaagggg ccagaggtta     1800

aatcggaagc agtggcaaaa aagcaagaac atgatgtgaa aactttgcag ctagtagaag     1860

aaaaaccagc agatggaaat aagacagtga cccacgtagt ggttgtcagt gcgccttcag     1920

ctattgccct tcctgtaact atgaaaacag aaggactagt gacatgtgag aaataaaata     1980

gcagctccac catggacttc aggctgttag tggcagtact gacataaaca tttgcaaggg     2040

aagtcatcaa gaaaagtcaa agaagacttt aaaacatttt taatgcatat acaaaaacaa     2100

tcagacttac tggaaataaa ttacctatcc catgtttcag tgggaaatga actacatatt     2160

gagatgctga cagaaaactg cctcttacag taggaaacaa ctgaacccat caataagaaa     2220

aaggatcgaa agggaccaag cagctcacta cgatatcaag ttacactaag acttggaaca     2280

ctaacattct gtaagaggtt atatagtttt cagtgggagg ggttgggatg ggtaatctca     2340

ttgttacata tagcaatttt tgatgcattt tatatgcata ccagcaatta ttactgtgtt     2400

cgcacagttc tcacttaact ggtgctatgt gaagactctg ctaatatagg tattttagaa     2460

tgtgaattga agaatggatc ccaaaaactt cagaaagagg atagcaaaaa aagatctagt     2520

gcgattttat atatatatat atatatatat acatacatat atatatatca tatagcttaa     2580

gctgatttaa aacaaaggcc ttagactaat tttcgatttt ctttcttgaa ataagctaat     2640

ggcttgtttg tgtaaagctt ttttattaaa agaaaaattt taaaaatctt gtacctagca     2700

cagtattgtt atagaatata catgtaacat tttatatggt agtttaagtc tgtcagtttc     2760

ttaattgtgg acaaattaac agttggctct ggccttttgc tgtaacatgc ctgtgtcact     2820

cacttagcct tggcatttgt gcagacatac cattttcagt tctgctgtca cttggaagtt     2880

caggctcagc atgaattttt ggcaggtagc tctaatacct ggagttttct ttgttttttt     2940

ttcttttttt tagttgaagt ttatgaggga aataccagtg ttcagttttg aactataata     3000

gtttgtatat tcaacatttg aagtatattc tattttgttg tactcttgtt tcaaagtgta     3060

ttcaagtagg ttttctgaaa tatagaaatg aaatttatct tctgttttgg tctctggtga     3120

tattttaaac aatatttaaa agtcagtata gaagtgtttt agttaggaag tgataaaaca     3180

tctctcttct ccttcccaac tactgcatga agaaattcta cttccattat attaatattt     3240

gg                                                                    3242


<210>  966
<211>  3092
<212>  DNA
<213>  homo sapiens

<400>  966
gccgttaggt ggtggggttt ctcagcccgg cggcgggagg cgggccggcc tcggcttcct       60

gtcggaggac gcgcaaggat ccgggcgtcg gagtgtgtgc gagtgcgtga gtgtgtgtcg      120

gtcgcacggc gtgtgtctcc ggccgcgggt tccgcctcct cccctgccgc cgctgctcac      180

ggtgtaagtc aatgtgaagc agcagctcca gccccgggat aaacatggcg acgtctctgc      240

atgagggacc cacgaaccag ctggatctgc tcatccgggc cgtggaagca tcagttcaca      300

gcagtaatgc acactgtaca gataagacaa ttgaagctgc tgaagccctg cttcatatgg      360

aatctcctac ctgcttgagg gattcaagaa gtcctgtgga agtgtttgtt cctccttgtg      420

tatcaactcc agaattcatc catgctgcta tgaggccaga tgtcattaca gaaactgtag      480

tggaggtgtc aactgaagag tctgaaccca tggatacctc tcctattcca acatcaccag      540

atagccatga accaatgaaa aagaaaaaag ttggccgtaa accaaagacc cagcaatcac      600

caatttccaa tgggtctcct gagttaggta taaagaagaa accaagagaa ggaaaaggaa      660

acacaaccta tttgtgggag tttcttttag atctacttca agataaaaat acttgtccca      720

ggtatattaa atggactcag agagaaaaag gcatattcaa gctggtggat tcaaaggctg      780

tctctaagct ttggggaaag cataagaaca aaccagacat gaactatgaa accatgggac      840

gagctttgag atactactac caaaggggaa ttcttgcaaa ggttgaagga cagaggcttg      900

tatatcagtt caaggatatg ccgaaaaaca tagtggtcat agatgatgac aaaagtgaaa      960

cctgtaatga agatttagca ggaactactg atgaaaaatc attagaacga gtgtcactgt     1020

ctgcagaaag tctcctgaaa gcagcatcct ctgttcgcag tggaaaaaat tcatccccta     1080

taaactgctc cagagcagag aagggtgtag ctagagttgt gaatatcact tcccctgggc     1140

acgatgcttc atccaggtct cctactacca ctgcatctgt gtcagcaaca gcagctccaa     1200

ggacagttcg tgtggcaatg caggtacctg ttgtaatgac atcattgggt cagaaaattt     1260

caactgtggc agttcagtca gttaatgcag gtgcaccatt aataaccagc actagtccaa     1320

caacagcgac ctctccaaag gtagtcattc agacaatccc tactgtgatg ccagcttcta     1380

ctgaaaatgg agacaaaatc accatgcagc ctgccaaaat tattaccatc ccagctacac     1440

agcttgcaca gtgtcaactg cagacaaagt caaatctgac tggatcagga agcattaaca     1500

ttgttggaac cccattggct gtgagagcac ttacccctgt ttcaatagcc catggtacac     1560

ctgtaatgag actatcaatg cctactcagc aggcatctgg ccagactcct cctcgagtta     1620

tcagtgcagt cataaagggg ccagaggtta aatcggaagc agtggcaaaa aagcaagaac     1680

atgatgtgaa aactttgcag ctagtagaag aaaaaccagc agatggaaat aagacagtga     1740

cccacgtagt ggttgtcagt gcgccttcag ctattgccct tcctgtaact atgaaaacag     1800

aaggactagt gacatgtgag aaataaaata gcagctccac catggacttc aggctgttag     1860

tggcagtact gacataaaca tttgcaaggg aagtcatcaa gaaaagtcaa agaagacttt     1920

aaaacatttt taatgcatat acaaaaacaa tcagacttac tggaaataaa ttacctatcc     1980

catgtttcag tgggaaatga actacatatt gagatgctga cagaaaactg cctcttacag     2040

taggaaacaa ctgaacccat caataagaaa aaggatcgaa agggaccaag cagctcacta     2100

cgatatcaag ttacactaag acttggaaca ctaacattct gtaagaggtt atatagtttt     2160

cagtgggagg ggttgggatg ggtaatctca ttgttacata tagcaatttt tgatgcattt     2220

tatatgcata ccagcaatta ttactgtgtt cgcacagttc tcacttaact ggtgctatgt     2280

gaagactctg ctaatatagg tattttagaa tgtgaattga agaatggatc ccaaaaactt     2340

cagaaagagg atagcaaaaa aagatctagt gcgattttat atatatatat atatatatat     2400

acatacatat atatatatca tatagcttaa gctgatttaa aacaaaggcc ttagactaat     2460

tttcgatttt ctttcttgaa ataagctaat ggcttgtttg tgtaaagctt ttttattaaa     2520

agaaaaattt taaaaatctt gtacctagca cagtattgtt atagaatata catgtaacat     2580

tttatatggt agtttaagtc tgtcagtttc ttaattgtgg acaaattaac agttggctct     2640

ggccttttgc tgtaacatgc ctgtgtcact cacttagcct tggcatttgt gcagacatac     2700

cattttcagt tctgctgtca cttggaagtt caggctcagc atgaattttt ggcaggtagc     2760

tctaatacct ggagttttct ttgttttttt ttcttttttt tagttgaagt ttatgaggga     2820

aataccagtg ttcagttttg aactataata gtttgtatat tcaacatttg aagtatattc     2880

tattttgttg tactcttgtt tcaaagtgta ttcaagtagg ttttctgaaa tatagaaatg     2940

aaatttatct tctgttttgg tctctggtga tattttaaac aatatttaaa agtcagtata     3000

gaagtgtttt agttaggaag tgataaaaca tctctcttct ccttcccaac tactgcatga     3060

agaaattcta cttccattat attaatattt gg                                   3092


<210>  967
<211>  3242
<212>  DNA
<213>  homo sapiens

<400>  967
gattttagct cttcccaagt tgtgaaaata gtgaaggatg cttagactac ttaacataca       60

aactgctttc tggttaatca tctttagaag actggatttc tggatatcta ctccactcca      120

tctctattga cttttaaaac atgataatgc aaacctataa cactggcaac catcagtgaa      180

cctttaattt cattgattaa tagcgtttga agcttcctca gggaataaca atgacatcag      240

cagtggttga cagtggaggt actattttgg agctttccag caatggagta gaaaatcaag      300

aggaaagtga aaaggtttct gaatatccag cagtgattgt ggagccagtt ccaagtgcca      360

gattagagca gggctatgca gcccaggttc tggtttatga tgatgagact tatatgatgc      420

aagatgtggc agaagaacaa gaagttgaga ccgagaatgt ggaaacagtg gaagcatcag      480

ttcacagcag taatgcacac tgtacagata agacaattga agctgctgaa gccctgcttc      540

atatggaatc tcctacctgc ttgagggatt caagaagtcc tgaattcatc catgctgcta      600

tgaggccaga tgtcattaca gaaactgtag tggaggtgtc aactgaagag tctgaaccca      660

tggatacctc tcctattcca acatcaccag atagccatga accaatgaaa aagaaaaaag      720

ttggccgtaa accaaagacc cagcaatcac caatttccaa tgggtctcct gagttaggta      780

taaagaagaa accaagagaa ggaaaaggaa acacaaccta tttgtgggag tttcttttag      840

atctacttca agataaaaat acttgtccca ggtatattaa atggactcag agagaaaaag      900

gcatattcaa gctggtggat tcaaaggctg tctctaagct ttggggaaag cataagaaca      960

aaccagacat gaactatgaa accatgggac gagctttgag atactactac caaaggggaa     1020

ttcttgcaaa ggttgaagga cagaggcttg tatatcagtt caaggatatg ccgaaaaaca     1080

tagtggtcat agatgatgac aaaagtgaaa cctgtaatga agatttagca ggaactactg     1140

atgaaaaatc attagaacga gtgtcactgt ctgcagaaag tctcctgaaa gcagcatcct     1200

ctgttcgcag tggaaaaaat tcatccccta taaactgctc cagagcagag aagggtgtag     1260

ctagagttgt gaatatcact tcccctgggc acgatgcttc atccaggtct cctactacca     1320

ctgcatctgt gtcagcaaca gcagctccaa ggacagttcg tgtggcaatg caggtacctg     1380

ttgtaatgac atcattgggt cagaaaattt caactgtggc agttcagtca gttaatgcag     1440

gtgcaccatt aataaccagc actagtccaa caacagcgac ctctccaaag gtagtcattc     1500

agacaatccc tactgtgatg ccagcttcta ctgaaaatgg agacaaaatc accatgcagc     1560

ctgccaaaat tattaccatc ccagctacac agcttgcaca gtgtcaactg cagacaaagt     1620

caaatctgac tggatcagga agcattaaca ttgttggaac cccattggct gtgagagcac     1680

ttacccctgt ttcaatagcc catggtacac ctgtaatgag actatcaatg cctactcagc     1740

aggcatctgg ccagactcct cctcgagtta tcagtgcagt cataaagggg ccagaggtta     1800

aatcggaagc agtggcaaaa aagcaagaac atgatgtgaa aactttgcag ctagtagaag     1860

aaaaaccagc agatggaaat aagacagtga cccacgtagt ggttgtcagt gcgccttcag     1920

ctattgccct tcctgtaact atgaaaacag aaggactagt gacatgtgag aaataaaata     1980

gcagctccac catggacttc aggctgttag tggcagtact gacataaaca tttgcaaggg     2040

aagtcatcaa gaaaagtcaa agaagacttt aaaacatttt taatgcatat acaaaaacaa     2100

tcagacttac tggaaataaa ttacctatcc catgtttcag tgggaaatga actacatatt     2160

gagatgctga cagaaaactg cctcttacag taggaaacaa ctgaacccat caataagaaa     2220

aaggatcgaa agggaccaag cagctcacta cgatatcaag ttacactaag acttggaaca     2280

ctaacattct gtaagaggtt atatagtttt cagtgggagg ggttgggatg ggtaatctca     2340

ttgttacata tagcaatttt tgatgcattt tatatgcata ccagcaatta ttactgtgtt     2400

cgcacagttc tcacttaact ggtgctatgt gaagactctg ctaatatagg tattttagaa     2460

tgtgaattga agaatggatc ccaaaaactt cagaaagagg atagcaaaaa aagatctagt     2520

gcgattttat atatatatat atatatatat acatacatat atatatatca tatagcttaa     2580

gctgatttaa aacaaaggcc ttagactaat tttcgatttt ctttcttgaa ataagctaat     2640

ggcttgtttg tgtaaagctt ttttattaaa agaaaaattt taaaaatctt gtacctagca     2700

cagtattgtt atagaatata catgtaacat tttatatggt agtttaagtc tgtcagtttc     2760

ttaattgtgg acaaattaac agttggctct ggccttttgc tgtaacatgc ctgtgtcact     2820

cacttagcct tggcatttgt gcagacatac cattttcagt tctgctgtca cttggaagtt     2880

caggctcagc atgaattttt ggcaggtagc tctaatacct ggagttttct ttgttttttt     2940

ttcttttttt tagttgaagt ttatgaggga aataccagtg ttcagttttg aactataata     3000

gtttgtatat tcaacatttg aagtatattc tattttgttg tactcttgtt tcaaagtgta     3060

ttcaagtagg ttttctgaaa tatagaaatg aaatttatct tctgttttgg tctctggtga     3120

tattttaaac aatatttaaa agtcagtata gaagtgtttt agttaggaag tgataaaaca     3180

tctctcttct ccttcccaac tactgcatga agaaattcta cttccattat attaatattt     3240

gg                                                                    3242


<210>  968
<211>  5878
<212>  DNA
<213>  homo sapiens

<400>  968
attgggtaca tgcgcagtgc cgctcgcgcg ggccgcgcca atcctgcagc gccttcaaca       60

ggtttcgggc ggcgaattcc agttctccgg gttttggggc tccctgcggg aggcagtgct      120

ggatctggga atctctagga aaggaaagag caaaggaggg gaaagatggg gggctgcagt      180

ctccacgtac gtccctcaaa gcgcgtccta aaacccggat aaccggagcg ctccccatgg      240

accacacgga gggctcgccc gcggaggagc cgcctgcgca tgctccatcg cctgggaaat      300

ttggtgagcg gcctccacct aaacgactta ctagggaagc tatgcgaaat tatttaaaag      360

agcgagggga tcaaacagta cttattcttc atgcaaaagt tgcacagaag tcatatggaa      420

atgaaaaaag gtttttttgc ccacctcctt gtgtatatct tatgggcagt ggatggaaga      480

aaaaaaaaga acaaatggaa cgcgatggtt gttctgaaca agagtctcaa ccgtgtgcat      540

ttattgggat aggaaatagt gaccaagaaa tgcagcagct aaacttggaa ggaaagaact      600

attgcacagc caaaacattg tatatatctg actcagacaa gcgaaagcac ttcatgttgt      660

ctgtaaagat gttctatggc aacagtgatg acattggtgt gttcctcagc aagcggataa      720

aagtcatctc caaaccttcc aaaaagaagc agtcattgaa aaatgctgac ttatgcattg      780

cctcaggaac aaaggtggct ctgtttaatc gactacgatc ccagacagtt agtaccagat      840

acttgcatgt agaaggaggt aattttcatg ccagttcaca gcagtgggga gcctttttta      900

ttcatctctt ggatgatgat gaatcagaag gagaagaatt cacagtccga gatggctaca      960

tccattatgg acaaacagtc aaacttgtgt gctcagttac tggcatggca ctcccaagat     1020

tgataattag gaaagttgat aagcagaccg cattattgga tgcagatgat cctgtgtcac     1080

aactccataa atgtgcattt taccttaagg atacagaaag aatgtatttg tgcctttctc     1140

aagaaagaat aattcaattt caggccactc catgtccaaa agaaccaaat aaagagatga     1200

taaatgatgg cgcttcctgg acaatcatta gcacagataa ggcagagtat acattttatg     1260

agggaatggg ccctgtcctt gccccagtca ctcctgtgcc tgtggtagag agccttcagt     1320

tgaatggcgg tggggacgta gcaatgcttg aacttacagg acagaatttc actccaaatt     1380

tacgagtgtg gtttggggat gtagaagctg aaactatgta caggtgtgga gagagtatgc     1440

tctgtgtcgt cccagacatt tctgcattcc gagaaggttg gagatgggtc cggcaaccag     1500

tccaggttcc agtaactttg gtccgaaatg atggaatcat ttattccacc agccttacct     1560

ttacctacac accagaacca gggccgcggc cacattgcag tgcagcagga gcaatccttc     1620

gagccaattc aagccaggtg ccccctaacg aatcaaacac aaacagcgag ggaagttaca     1680

caaacgccag cacaaattca accagtgtca catcatctac agccacagtg gtatcctaac     1740

taccgtcttt ttgctaggac ttaaactgac ttgagtgtgg caaaaagtta acaaaaaagg     1800

agaaaaaatg aacaatcgtt tgtggtttct tgggaaaact tttcatacca ggtgatacta     1860

ttcaaaaacc ccgttgtctc cctgcaagtg ctgatttgaa atgcagaagc cacagtaaaa     1920

aaaaaaaaaa aaaaaaaaaa aaagaaaaaa aaatcaaaat gtataaatat tggaaatcaa     1980

gtttttcagc tgttttgttg gttggttggt tggtttttgt ttggttttgt ttaaatgggc     2040

aagaagtaaa taatgtggct ggaatacaag ttgaacaaac tagaagacac aaatctaaca     2100

tagtttttat ggaccaagga acttgtatat tgtataagct ttagtaaaag gtacattttc     2160

accatacctt tttttatatc acggtattat agtacacctt gttaccaaat aggttgttct     2220

cttccccacc cacctttgag cttttgctct aaaatacatt caggttccaa gcctgaccat     2280

ccttgtttaa tctatcatac tcttccaggt tttttttttt tggtctaagg ctggaacttt     2340

tttctttttt ttcagctgaa gtcttatgac ttttcatgag tcaaaattgt ttggatttca     2400

gcaagtcaaa tcttgcaaag gcctgcatat tttttttaag attatatgaa gtctgtgcaa     2460

aagctttaaa aaaatgcctc tgccttgcct gcaatacatg caatgtatgt taacttagtc     2520

tctcttctca gacactgttg gtagttattt ctgtgttttc ctttttttaa aaaaaaatat     2580

ggacttattg tggttatctg agaggttcta acattcacat gcaatttggt gtggccattt     2640

agctattaat gagttaatgg cgcagaactt gttgatattt gaagtgttct ctcccctttt     2700

cccatgacgt aaatacatag gtgtgttcca ggatttgttc aggtttttcc cccctcctaa     2760

tcttgtacat aacttgtatt atgtgtaagt taaacatttt attttgaact tggaatgttc     2820

ccagtgattt cattcagcag ggtattttct gccttgttgg caagtgacaa aaaatatggg     2880

aagtatttgc taccagttgg tagatggtgc ccttaatggt agaatgagga aaatgtccgc     2940

aaaagcatgt tttattatct ttactttttt ggggggttgg agggggtagc ctagccagaa     3000

catcattgta atcttaaaac ataagatgct tttattagat gatcaactaa aatagctgga     3060

agacagtact ttagaaacag atagttgtaa gattataaaa tgcaaatgta acttatgttt     3120

tcattttttt ctctgccttt tttgtttgtt tgttttctct tttccagtac tgagcatctc     3180

cacaaatgtc tcctaactca gaaaatgttt cttttctttt cagttgagat ttggttgcat     3240

tcagggttgt aggttggcct tgcttgctaa ccccgccggt tttaccgtgc tttcattcct     3300

gaactttgtt tatgcctttg tttggtttct tcgaaattgc agcagactca ttgggctaca     3360

tttagtacag gaaccacgtg tgtaatgtta tacaacacag tctagtaata caatcatccc     3420

tcttagagta aaaactacct ctagattgtg gtaagctttt actgtcccat aaaacaggag     3480

ccacagtacc ttatgaatgc aaaactgtaa cttcctacag tgtttcccta cagaacattg     3540

tctttctggt gtcctgggct gttttgaaaa agtttccatt aatagacttt ttagaaatta     3600

ttattagtag catttttttt ccagctttgc tgtcttcatc actcactcta tgctcagact     3660

atgccactgt aaatattctt cctaacatct ttaaatcgcc ttttcctcag ttttcaaggg     3720

gaaggtcatt tgtaaagcac gttaggtggt taaatcagtt attgcggttt tctcttactg     3780

caagcctttt taatcacccc caggctgcat tttattctat atcgcctttt ttcttcaaat     3840

ctgctccaat cactcacttc tctcttataa gctaatcctg cctcacacct taaatctgtt     3900

tcagtgatca agggcagaac tcattgtggc cttatctttc tttgttgtaa ttgttcactg     3960

tctctttctt acagaccact tatttctgag tagtagttat tcctctctat ggagtcatgg     4020

caggaatcat tacacagtgc ttttgttcag agcatggaca tgttcctagt gctgctttgc     4080

tttaacggcc acaagtttcc tccacttcct aggtttggta tttagttaag gaatcatatt     4140

aaattaacca ataacaaaag agatactttt gaagaacaaa ctattcctta cccatttttg     4200

tagctcaaaa ataatttttc aagttcatga ccttattaaa atgaacttgt gtttttttaa     4260

caaacatgta tgttttattt tgatagtttc tttccgtaag ataattgaaa tattatactg     4320

taaacccttt tcttttcttt ttttgaaaag tccaagaatg tacttataca ggcatttttc     4380

cccacctatt tttggccatt ctcataccac agactaaaga gtgaaatgat ttgtccattg     4440

tagcttattg tttatcagta gttcttttgt cagctgctta cattttttct ttcatggttt     4500

tgtgaatcat tttcagtatg taatttatag gaaccttgtc ctctggttat agtagactgt     4560

gtgccctcct ccagtgatgg cattattaga catgctggtc atttaccctc agaaagactc     4620

tcttattaga atggtgagtg cttcagttat agtatgtttg aatttttaaa aaattctgtt     4680

ttagaaatgt atcttatgct ctcatgacta tgcagtttct aaacatacac atagaagctg     4740

agtctctgat ccaatatgtt tttatttgtt ccatttaatt tatcacatag attgggaagg     4800

caagctaaaa gccttaaaaa tgccctttat attttgagtg atttcagcgt tgaacactag     4860

tatactatct aaatttgctg ctcactttct ttaaactgtg gcaattaaag gcatgtttat     4920

acatgactta atcgtgaaat gtttgtcact cttactgcac agacttatct gcaatcataa     4980

ctggttagtt tttttgtttt gttttgtttt attgttttta atgaaactgg taccatctgt     5040

gctttcacaa aaaacttcca atgccatttt tgagaactaa cctaactagt catgctaacc     5100

agaaaatcca ctggggagga ggttcctttt gaaacaaaat gctgttcagt tagtaaccaa     5160

gttactttga ttgcaaaagc agctgtgttt ctgataagta ctgaacaaat gtgtgtaatt     5220

ttctgtgcca gacttatgac tttgttttca agcactgtaa tgtgggatgg atggttagaa     5280

acaataatat attagggttt ctgtttaacc ctttcaggac tgaactgtat ctccttttgt     5340

taattttccc ctgtgttgtg ataaatgttt gccagcattc agtactgtgt tggtccagat     5400

gtaggtttat atgctcattt ttagcttatt tcttgtacct tgcagcatgc tctacgcatt     5460

cagtccttaa ggggtttatt ttacaaactg tgcgcctgta aggtttatta gcaataagat     5520

agaaaattga gcaagtttat accataattt tgtagaaaaa aagaatctgc tcagttccat     5580

atttcatccg tgaaaaactt gcaatacgag cagtttcaag gaataaataa aaaggaaatg     5640

taaaccattg taaaagtctt ctgtcgaatg tgcctgatgc atgtattatc gtcttttatt     5700

tcagaatact tcataaagat aaaattaaat tctatattat agttggtgta tttacaatct     5760

taccatgtac atcacatcaa agtgatagct ctactaattt aatttccttg tcaatgtttt     5820

taactatata gtgctttaaa gagatttttt ttccctgtgt aaaaaaaaaa aaaaaaaa       5878


<210>  969
<211>  954
<212>  DNA
<213>  homo sapiens

<400>  969
agacgttctt cgccgagagt ggtcggggtt tcctgcttca acagtgcttg gacggaaccc       60

ggcgctcgtc ctgcaccccg gccggccgcc catagccagc cctccgtcac ctcttcacca      120

tgccctcgga ctgccccaag gcccccgccg cagctccagc gccgcgtagc caccactgcc      180

gctgccgccg cctctcctta gtcgccggca tgacgaccgc gtctacctcg caggtgcgcc      240

agaactacca ccaagactca gaggccgcca tcaaccgcca gatcaacctg gagctctacg      300

cctcctccat ttacctgtgc gtggcttact actttgacag cgatgatgtg gctttgaaga      360

actttgccaa atactttctt caccaatctc atgaggagag ggaacatgct gagaaattga      420

tgaagctgta gaaccaacga ggtggccgaa tcttccttca ggatatcaag aaaccagact      480

gtgcggggag aatgcgatgg gagagcgggc tgaatgcgat ggattacatt tggaaaaaat      540

tgtgcatttt gcattacatt tggaaaaaaa tgtgaatcag tcactactgg aactgcacaa      600

actggccact gacaaaaatg acccccattt gtgtgacttc attgagacac attacctgaa      660

tgaacaagtg aaggccatca aagaattggg tgaccacgtg accaacatgc acgagatggg      720

agcgcccgaa tctggcgtgg cagaatacct ctttgacaag cacaccctgg gagacagtga      780

taatgaaagc taagcctcag gctaatttcc ccatagccat agggtgactt accttgtcac      840

caaggcagcg catgtatgtt ggggtttcct ttaccttttc tataagttgt tccaagacac      900

ccacttaagt tctttgattt gtaccattcc ttcaaataaa taaatttggt accc            954


<210>  970
<211>  3175
<212>  DNA
<213>  homo sapiens

<400>  970
tttccttttc cggctacggg tccccaagcg gagcgggagg ccggaccggg gagccgagcg       60

gcggcgtcgg cggcgtcggc ggcggcggcg acggcggcgg gggcggtaat ggcggagctg      120

gtgcaggggc agagcgctcc tgtggggatg aaggccgagg gcttcgtgga tgccctgcac      180

cgggtccggc agattgctgc taaaattgat tcaattcctc acttgaataa ttccacacct      240

ctagtggacc cctcagtata tggatacgga gtacaaaaac ggcccttgga tgatggagta      300

ggtaaccagt taggggcctt ggtacatcaa aggacggtaa taacggaaga attcaaagtg      360

cctgacaaaa tggttggatt tattatcggc aggggaggtg agcagatttc acggattcaa      420

gcagaatctg gttgcaaaat tcagattgct tcagagagtt ctgggattcc agagaggccc      480

tgtgtactta ccggaacccc agaaagtatt gaacaagcca aacggctcct gggacagatt      540

gtggaccgct gtcgaaatgg acctggcttt cataatgaca tagacagcaa cagcacaatc      600

caggagattc tcattcccgc atctaaagtg ggtctggtca tcggcagagg aggggaaaca      660

atcaagcagt tgcaggagcg gacaggggtg aagatggtca tgatccagga tggcccattg      720

cccacgggag cagacaagcc tcttcgtatc actggagatg catttaaagt acagcaagca      780

agagaaatgg tactagagat tatccgagaa aaagaccaag ctgactttcg gggtgtacgc      840

ggcgatttca actctcgaat gggaggaggc agtatagagg tatctgtgcc taggtttgct      900

gtggggattg taataggaag aaacggggaa atgatcaaaa agatccagaa tgatgctggt      960

gtgaggattc agtttaaacc agatgatggg attagtccag aaagagctgc ccaggtcatg     1020

ggccctccgg atcggtgtca gcatgcagcg catatcatca gcgagctgat tcttacagcc     1080

caggaaagag acggctttgg aggcctggca gcagccagag gaagaggtcg tggccgtggc     1140

gactggagcg tgggagcccc tggtggcgtc caggagataa catacacggt gccagccgat     1200

aagtgtggcc tcgtcatagg caaagggggt gagaacatca aaagcatcaa ccagcagtca     1260

ggggcgcacg tggagcttca gaggaacccc cctcccaaca gcgaccccaa cctgcggaga     1320

ttcaccatca ggggggttcc ccagcagatc gaggtggcca ggcagctcat agatgagaaa     1380

gttggcggga ccaatctcgg agcacctgga gccttcggac agagtccatt cagccagcca     1440

cctgccccac ctcatcaaaa tacctttcct ccaaggagct ccgggtgctt cccaaacatg     1500

gctgccaagg tgaatgggaa cccccacagc acccctgtga gtggtcctcc ggcctttctg     1560

acccagggct ggggcagcac ctaccaggcg tggcagcagc ccacacagca ggtcccaagc     1620

cagcagagcc agccgcagag cagccagccc aactacagca aggcctggga agactattac     1680

aaaaaacaga gtcacgccgc cagcgctgct cctcaggcca gctccccacc ggactacaca     1740

atggcctggg cagaatatta cagacagcag gtcgctttct acggacagac gttagggcag     1800

gcgcaggccc acagccagga gcagtaggac agcgtcctcg tggccaactc tcccctcaaa     1860

atcattgtca aagaaaacct atttgtaaca gaggttttta catttgcaaa ccttttgatg     1920

aagaactgtt gttttgttct gtgaaacact atatttagat taacggaatt tttctaaaaa     1980

tcaggaaaat tagttactaa aaattgctga tcatttttgt ttcattattt ttgttatttc     2040

aaatgtataa gctctgggat tctttttgga gcaataccta caaagtcagg caccagaatg     2100

tgcctcagag ctgtgacatt tcaacatgat ggttttggtt tggtttggtt ttgtgtcctt     2160

tttatttgca gttttttctg ttgcaacaga aagtggcttg gaagtcttag gtggtatgta     2220

acaaattctt tttaaaaatt ttaaagcagt atttaagtat tcttaaatgt gtaaattcat     2280

ttaatgtttt acttctaatt tcttgtatct tggctgtctg gttttattgc atttttaaaa     2340

aaactgaact attatgtatt gtaatgaatg atgtgaattc tgaactgaga cagataattg     2400

tattgctgtc caacaggggt tgggaggggc attttgtagg gtttgtataa tttctagagt     2460

tcgaaagggg taatataaaa atgtgctcgt gtgtttagcc tacgtttttc tcatgcctcc     2520

attaccagtt gcaattgtgt atctaagacc tccaagcttg tttttaaaac aaaacaaaaa     2580

acctttctct attatctcag aaatataaat actgttattt ttaatattaa gaaattcaat     2640

ataactttta acacacactg tggaacatta aaccgtataa aaatgtagtt ataactattt     2700

ttaattccaa ggtgttgttt gcttttttct tttaaatatt ttcttaatat tttgtcagat     2760

taactagatg aataaataaa tctagtatta accgcattat gaattaaata attttgattt     2820

aatgaaaggg ataatatgat ttccagtgtt tactgtagtg tatcttgtac agataacatg     2880

tatttttaaa ggaaaaaaaa cggaattgaa gctatttttt cttgcatttc taattgacct     2940

gagggacatt ccgtttgaaa tgtactgaag ttacagtttc tggttttttc tccttatttt     3000

tcttataatg cttgaaatgt ctaactatta aaaaagacaa ttggaaaatg ttatgcatgg     3060

ggtttttaag aaaacaaagt gttcttttta tttgactgac aattcatttt acactctata     3120

taataaaatc tccacaaggc atcttgtggg caaagtcaaa aaaaaaaaaa aaaaa          3175


<210>  971
<211>  3993
<212>  DNA
<213>  homo sapiens

<400>  971
gatttgggag ttgggaggtg agatgattgg agtgaagaga gttaatgtca tggaaaggaa       60

aagctgtctg aagaaaaata cacattttaa tgtccctctt cagccgtgcc tgctgagagc      120

tctcctggga tgataagtga aagtgtttgg attttttttt aagttttaaa actctgccaa      180

agcattgctc agtgtatctg ggcagcccct tccggcaaaa cgcagcagta gcagaggcag      240

cttctgagag cctgggcagg cagcagctgg ctgaccaagt ccactggaag agaaggcttg      300

tgccagccgg gagaaggaag ccggggacag gatgaaagca acaacacctt tgcagacagt      360

cgaccggccc aaggactggt acaagacgat gtttaagcaa attcacatgg tgcacaagcc      420

ggatgatgac acagacatgt ataatactcc ttatacatac aatgcaggtc tgtacaaccc      480

accctacagt gctcagtcac accctgctgc aaagacccaa acctacagac ctctttccaa      540

aagccactcc gacaacagcc ccaatgcctt taaggatgcg tcctccccag tgcctccccc      600

acatgttcca cctccagtcc cgccgcttcg accaagagat cggtcttcaa cagaaaagca      660

tgactgggat cctccagaca gaaaagtgga cacaagaaaa tttcggtctg agccaaggag      720

tatttttgaa tatgaacctg gcaagtcatc aattcttcag catgaaagac cagcctcctt      780

gtatcagtcc tctatagaca gaagcctgga aagacccatg agttctgcaa gcatggccag      840

tgacttcagg aagcggagga agagcgagcc tgcagtgggt ccaccacggg gcttgggaga      900

tcaaagtgcg agcaggacta gcccaggccg agtggacctc ccaggatcaa gcaccactct      960

tacaaagtct ttcactagct cttctccttc ttccccatca agagcaaaag accgtgagtc     1020

ccctagaagt tactcatcca ctttgactga catggggaga agtgcaccaa gggaaagaag     1080

aggaactcca gaaaaagaga aattgcctgc aaaagctgtt tatgatttta aggctcagac     1140

atctaaggag ttgtcattta agaaaggaga tactgtctac atcctcagga aaattgatca     1200

aaattggtat gagggagaac accacgggag agtgggcatc ttcccgatct catacgtaga     1260

gaaactcaca cctcctgaga aagcacagcc tgcaagacca cctccgccag cccagcccgg     1320

agaaatcgga gaagctatag ccaaatacaa cttcaacgca gacacaaatg tggagctgtc     1380

actgagaaag ggagatagag ttattcttct taaaagagtt gatcaaaact ggtatgaagg     1440

taaaatccca ggaaccaaca gacaaggcat cttccctgtt tcctatgtgg aggtcgtcaa     1500

gaagaacaca aaaggtgctg aggactaccc tgaccctcca ataccccaca gctattctag     1560

tgataggatt cacagcttga gctcaaataa gccacagcgt cctgtgttta ctcatgaaaa     1620

tattcaaggt gggggggaac cgtttcaggc tctgtataac tatactccca ggaatgaaga     1680

tgagctggag ctcagagaaa gtgatgtcat tgatgtcatg gaaaagtgtg atgacggctg     1740

gtttgtgggg acctcaagaa gaaccaaatt ctttggtact ttccccggaa actacgtcaa     1800

gaggctgtga attgcgctcc ctccttctgt agaggccgcc tgccagccat gcacctgcgt     1860

caacgcgcct gaaacacccc gcgggcctcc cgttgtcatg ccttacggtt tccaatgcgc     1920

cgtcaccatc tccacctgcc accaaaccac cagcagagta gccgccgctg ctgtgagcct     1980

ggggacgaca tggcaggctg gtccccctcc gtgaaagtgt ggattcctac ttcctgctct     2040

aagctttgac acgtcaaaat gtgggatcag aaagaaaaaa atcatgatat ttaaaaatgg     2100

tcaaatattt gaggcaaaaa aaaaaaaaaa aagtgtctcc aggaggctgt ccagcctcgt     2160

ggctccattt caacatctcc ccccaggcga tgttctcccc caagacgacc agaaaattgt     2220

ttattgggga atgctgtggt ttgcattttc atattcttcg cttggcagtg tgtattcttt     2280

tcacaagttt gcctagtgtc ttggtttaca caatatgaca actgtaactg tactttagct     2340

attgtttgcc tgcacataca tgttgtaata tgcacagtga ttacaacctt taaagcaaga     2400

ggaggcgagt taatttggat gagtgtgatt ttgctgattg aatgtgagtt ttcaaatagg     2460

agtctttttc tgcaatttgt ttgcattttt tagaagtgca aacagtaagt aaataaaagc     2520

cttcggtaat aatcatgaca atacaagagg ctgagctagg ctacagggga aaactattgt     2580

gttgtaaagt tgcatcgcta ttttatatta aaatgtaatg atcagcatca tgaacaatga     2640

gctcttagtg ttttatttat ctgaaaaaat gtaagtaaaa gcagtgttag tgagaggtgc     2700

aaagaattat tctaacagac acctgaaagt atctgtaagc aatactagta ggtaagattt     2760

cactgtgtgt acacatacac atttgagatt gtatgagaac atataatcca tatgatatgt     2820

tgtacatttt atggaaatgt aatagaatct cacacattat tttatagaaa tagagtacag     2880

aagcatcaca agtattaaag ttggttttag caaggattag gattactaca attattttta     2940

ctataataat tatttttctt ctatggaact cagaatcctg gctacatttg aggacaggaa     3000

tatgttgagc ctgattttcc tggtgtgtgt aaaatatttc ctaggaataa attaggcact     3060

ttttagaagc aatgttaaat cattcaggtt ttattttctg ccctgaagca gaaatttaaa     3120

aaatgatatt gggacctgga aggtttaata tggttcacag tgcctgaatt acacctgctc     3180

cgaaaactag ctttgtattt cttatgactt tgcataagaa ctgttcatct ttggatcttg     3240

agcaccttac agataaaact ttttatggca tctctttcat ggacagtgat attgatcttt     3300

tcacaatgta cgtagcctct agaattttgt acatatgttt gctctttttt tgtacagact     3360

agttgttgag aaaacagggg cgtttcctaa tttggtcttt atcctgcgac aacactttca     3420

gcagactagc ctctccttat ctcacagatc acaagcaccc ctagatagtg tgattctgtc     3480

agatagcatt tatgcaaaaa tctatgaagt taaaagatcg tagaagccaa atgaaatgta     3540

catatctact gactgatgac aagggaattt cattaggaag aaggtaaaga aacatcgttg     3600

agtagcctac cttgatttct gtcaagttca taaccagctt catattttaa aggcttcagg     3660

tttgaaatta agtcaactgc atgcagcttt gctgataaat gaataattct ctttgatgcc     3720

atttatgaga aaagacttca atatctgttg cctgtcatat ttaagaaaaa ttactgtttc     3780

tactctctgt atctgatttt aaaagaaaaa actattcata cctggcttcc aggtaattga     3840

ctttgaattc ttacaagcaa aggtcattgt gtttttcttg aatagacatc taataaattt     3900

tgcttggaag tatacttcag tttttcttct tgacatttat ctttataaaa attgtgtatt     3960

ttattccaac ttgttaaact aagagaaaat gca                                  3993


<210>  972
<211>  6184
<212>  DNA
<213>  homo sapiens

<400>  972
ggcgacggcg gcggccgtcc tcatcccggc gcttgagagg acgcggggct gcgcaaatgg       60

cttgtcccgc tctcggtctg gaagctcttc agcccctgca gcccgagccg ccccccgagc      120

ccgccttctc cgaggcgcag aagtggattg agcaagtaac tggcagaagt tttggtgata      180

aagattttcg gacaggttta gaaaatggaa tcctcctctg cgagttgctg aatgctataa      240

agccaggact tgttaaaaag atcaatagat tgcctacccc cattgcagga ctggacaata      300

ttatcttatt cttgagaggt tgtaaagagc tcggccttaa agaatctcaa ctttttgacc      360

cgagtgacct ccaggataca tccaacagag taacagtcaa gagccttgat tatagtagga      420

agctgaaaaa tgtattagtt accatttact ggctgggaaa agcagcaaac agctgcacat      480

cctacagcgg aacgacacta aacctgaagg agtttgaagg attgttggct cagatgcgaa      540

aggacactga tgacattgaa agtcctaaac gcagtatccg agacagtggc tacatcgact      600

gctgggattc cgagcgcagc gactccctct ctcctcctcg ccacggcaga gatgattcct      660

tcgacagcct ggattccttt ggctctcgct ctcggcagac gccttcacca gatgtagtcc      720

tcaggggaag cagcgatggg agaggaagcg actctgaatc cgacttgcct catcggaagc      780

tgccagatgt gaagaaggat gacatgtctg cacggcggac ttcccatggt gagccgaaat      840

cagcagtgcc ttttaaccag tacctcccga acaaaagcaa tcagacggcc tacgtccccg      900

cgcctctgag aaagaagaaa gcagagagag aggaataccg caagagctgg agtaccgcca      960

cctccccgct gggtggggag aggcccttca gatacggtcc gagaactcct gtgtctgatg     1020

acgcagagag caccagcatg tttgacatgc ggtgtgagga ggaggccgcg gtgcagccgc     1080

acagcagggc ccgccaggag cagctgcagc tgataaataa ccagctgagg gaagaggacg     1140

acaaatggca agatgacctg gctcgttgga agagtcgtag aagaagtgtt tctcaggact     1200

taatcaagaa agaggaagaa aggaaaaaaa tggagaagtt actggctgga gaagatggga     1260

caagtgaacg aaggaaaagc atcaaaacct acagagaaat tgttcaagaa aaagagcgga     1320

gagagagaga gctgcatgaa gcatataaga acgctcggtc ccaggaggag gcagagggga     1380

tccttcaaca gtacattgag aggttcacca tcagtgaggc tgttctcgaa cgcttggaga     1440

tgccaaaaat tctggaaaga agccattcaa cagagccaaa tttatcctcc ttcctgaatg     1500

accccaatcc catgaaatac ctgcggcaac agtcactgcc tccacccaaa ttcactgcca     1560

ctgttgaaac caccattgct cgtgccagtg ttctggatac cagcatgtca gcaggcagtg     1620

ggtctccaag caaaactgtc actcccaaag cagtgcctat gctgacaccc aagccttact     1680

cccagcccaa aaattctcaa gatgttctga agacctttaa ggtagacggg aaagtcagtg     1740

tgaatggaga gacggttcat agagaggagg agaaggaaag agagtgtccc acggtggcac     1800

ctgcccactc cttaaccaaa tcccagatgt ttgaaggtgt ggccagagtg cacgggtctc     1860

cactggagct gaaacaagac aacggtagca tcgagatcaa cataaagaag ccaaactctg     1920

ttccccaaga gctcgcagca accactgaga aaacggaacc gaatagtcaa gaggacaaga     1980

atgatggtgg aaaatcaaga aaagggaata tagaacttgc ctcatcagaa ccacagcatt     2040

ttacaacaac tgtgactcga tgcagcccga ccgtggcctt tgtggaattt ccctccagcc     2100

cccagctgaa gaatgatgtg tcggaagaaa aagaccagaa gaaaccagaa aatgaaatga     2160

gtggaaaggt ggagttggtg ctgtcacaaa aggtggtaaa gccaaaatct ccagaacccg     2220

aagcaacgct gacatttcca tttctggaca aaatgcctga agccaaccaa ctacatttgc     2280

caaatctcaa ttctcaagtg gattctccaa gcagtgagaa gtcacctgtt atgacacctc     2340

agtttaagtt ctgggcatgg gacccagaag aggagcgcag gcgacaggaa aaatggcaac     2400

aggaacagga acgtttgctc caggagagat accagaagga gcaggacaag ctgaaagaag     2460

agtgggaaaa ggcccaaaag gaggtggaag aggaagaacg cagatactat gaggaggagc     2520

gtaagataat tgaagacact gtggttccat ttactgtttc ttcaagttcc gctgaccagc     2580

tgtctacctc ttcctccatg actgaaggca gtgggacaat gaataagata gacctgggaa     2640

actgtcaaga tgaaaaacaa gacagaagat ggaagaaatc attccaggga gatgacagtg     2700

acttattgct gaagactagg gaaagtgatc gactggagga gaagggcagc ctaactgaag     2760

gggccttggc tcattctggg aaccctgtat caaaaggagt ccatgaagac catcagctgg     2820

ataccgaggc tggggcccca cactgtggaa caaacccaca gcttgctcag gatccatccc     2880

agaatcagca gacatcaaat ccaacgcaca gttcagaaga tgtgaagcca aaaaccctcc     2940

cgctggataa aagcattaac catcagatcg agtctcccag tgaaaggcgg aagaaaagtc     3000

cccgagagca cttccaggct gggcctttct ctccctgttc tcccacccct cccggtcagt     3060

caccaaacag gtctataagt ggaaagaagc tgtgctcttc ctgtgggctt cctttgggta     3120

aaggagctgc aatgatcatc gagaccctca atctctattt tcacatccag tgtttcaggt     3180

gtggaatttg taaaggccag cttggagatg cagtgagtgg gacggatgtt aggattcgaa     3240

atggtctcct gaactgtaat gattgctaca tgcgatccag aagtgccggg cagcctacaa     3300

cattgtgaca cggctttcaa gcttccggat cactcaccat ttctttactg agagtgtccc     3360

ctggcaactg cttaacaaaa tcccaagctc aggggcttct cagcatttac ctaatttctg     3420

aaaggctctt ctgaaaggtg gtatctgttc tttcgtagca cagtgtttat gtttttcctg     3480

tttattgttt tggttttttt tttttttttg catttgcaca gtatacacaa aagaatatgg     3540

ggttgtaatg atcctgaata gctcaaaaaa ggttttagca tggtcaaaca ggcttatggt     3600

ttaaaatgtg ttattctctt ctttgggaat tagctaaatg atgcaataaa cctgttttgt     3660

tttagaatgt ctaggaatta aacactttat gtttacagaa ttgagctgca gaaagtgcaa     3720

gacatgccaa tttgagacac acggtcttct aagactgaag gataaattta atgcatttca     3780

gaaactaaac atcacagcaa gctctatctc tgagctataa tttgttttta atgcaaagac     3840

actagtttga taatatatac tgtaatcctg aaacatttgt gttacttacc tttggaggta     3900

gaaattatac caataaatta ttgcaccgtt agtattagat tctgtgtacc ttggaagtta     3960

tgtcattaat ataggctggt tcatcaaata aagcaaaacc ttgcaatatc agctagattt     4020

acactccggg acgttgccca aaggtaggaa gaaagcagag ggaaatattt cagtcatcat     4080

ttccaaagtc attatcaaaa tctgtgagga agtttaatct tccaaagagt caatgtcaga     4140

catcaggcct ctgttgcctg cttctctcga ggcactagat taggagtctt caataagaga     4200

cttaacatga ggtatatgga agatgaggca ccgagataag ttcatcatta ggtgtgagca     4260

ctgctcaccc ttgctggcaa gttctcctta agggcctgaa gcacaggtgt ccaaagaaaa     4320

gcgttaagtc catcttaata gaatctatgt ggtatatgat gtggtcagcc cctggtctgt     4380

gatcagcaag aacctacagc acagattatg ccctgcccac ttcaatgaat acctactctc     4440

ctccattctc catcactttt tttgctatca agaactccgg accttgccca tggagaagtt     4500

tagagaggaa ctcttgtgga gagctggttt attttctgcc ctgtgcgacg agtttcagct     4560

ggccaagaaa ggagtcaagt tattaaaaag catcacaatg tagatctcca ggctggtttt     4620

ttgttttttg ttgttaagac tggggaaagg gggactattt attctgcctt aaatcaatgg     4680

caaataagtc aagatgacat tttgtgaatg tagactatgg atacactcct aatagattga     4740

tgtagtcata aaagggggtc aagtagatgt ttttctgtta tgtaagcaat aatttttccg     4800

tgtcttattg agtatggcta gcgattattt attacatgct agatgggttc tttgcatgtg     4860

ggttccatat aggtgcagaa atttcctcag ccactggagg gatttcgacc atatttgtca     4920

tttggatgag ctgttattag attgaaatct acacatcatt tcattaaaaa ttgtgcctta     4980

gaaaacgcaa agctgttgca catggcgata aattatggat gcagtacatt gaagagagat     5040

gaagtcactt ccaagtttcc aagacttctc atggaggtgt ttgctgtttt acaggaaaaa     5100

ataaaaataa aaaaagaaaa aaagaaaaaa ttaaaaagaa aaattgtttt gaaaatgtac     5160

agatcaagtc caatattttg attatccacc tgcatgtttt attaaatatt ttgataatgt     5220

ggatgtttac actttgcatg atattagcag agtaccacta gtaatgcaca aacatgtaca     5280

atatggtcat tcataaccga tttttataga atacttttta catgtgcaac tccatccgtt     5340

atgtaaggat tacatgaata ttgcacattc ccttctggtt tcacaaaccc atttatacat     5400

atttcttagt gaggctcatt gtacatgtat tgaagctaga atcgagtcaa gaaaaataaa     5460

gccccattct ccaactgcaa aatgtgcttt cccataatga acactagtca ccagcacaga     5520

ataatctcca acattttcta aattctaatt gccaactgtt tctatttata tttgatttat     5580

atttcatttg gagtctgtta catggcagct taggcagact agatcttgtt ttttccaatg     5640

cagcataatg agtatgatct atttcttttc aaataatctt tgagatccca ggaaaaaaaa     5700

aatgctctgc tccattgagc tataatgtaa atgtgtttgt ttaaaaaaca ggtgaggcaa     5760

gtgagtgatt tattgttcct gaggaagtat atctgatttt ttttctcata ctccaaaagc     5820

tagtccctac tctttaataa aaataatggg taactttttg tttttcacta gcgaacttcc     5880

atgacatttc ctttctatgt agtgtgatta atgcaataca tattatagtt atctatacac     5940

agtgtaagat ttaacaaact gaaatgatcc acctcatatg tgagtccgtc caaaagatgt     6000

tactgctctg ggtgggccag tgttctatat cggttatact aactttcatt taaagtattt     6060

attctaaaat gcctctgaga aacagtaaaa aataaaaaca acaagttgtc taaaatgcaa     6120

cagcttttat agtaaatgta catttataaa taaaatactc aaatcaaaaa aaaaaaaaaa     6180

aaaa                                                                  6184


<210>  973
<211>  4369
<212>  DNA
<213>  homo sapiens

<400>  973
ggctcaaata tagttcaaga caacagagac aaagctaaga tgaggaagtt ctgtacagtt       60

taggaaatag aggctttcaa agataattcg cagtgatgtg aaactggcct cccaagccct      120

gataacaaca tggccaacgc cctggccagc gccacttgcg agcgctgcaa gggcggcttt      180

gcgcccgctg agaagatcgt gaacagtaat ggggagctgt accatgagca gtgtttcgtg      240

tgcgctcagt gcttccagca gttcccagaa ggactcttct atgagtttga aggaagaaag      300

tactgtgaac atgactttca gatgctcttt gccccttgct gtcatcagtg tggtgaattc      360

atcattggcc gagttatcaa agccatgaat aacagctggc atccggagtg cttccgctgt      420

gacctctgcc aggaagttct ggcagatatc gggtttgtca agaatgctgg gagacacctg      480

tgtcgcccct gtcataatcg tgagaaagcc agaggccttg ggaaatacat ctgccagaaa      540

tgccatgcta tcatcgatga gcagcctctg atattcaaga acgaccccta ccatccagac      600

catttcaact gcgccaactg cgggaaggag ctgactgccg atgcacggga gctgaaaggg      660

gagctatact gcctcccatg ccatgataaa atgggggtcc ccatctgtgg tgcttgccga      720

cggcccatcg aagggcgcgt ggtgaacgct atgggcaagc agtggcatgt ggagcatttt      780

gtttgtgcca agtgtgagaa accctttctt ggacatcgcc attatgagag gaaaggcctg      840

gcatattgtg aaactcacta taaccagcta tttggtgatg tttgcttcca ctgcaatcgt      900

gttatagaag gtgatgtggt ctctgctctt aataaggcct ggtgcgtgaa ctgctttgcc      960

tgttctacct gcaacactaa attaacactc aagaataagt ttgtggagtt tgacatgaag     1020

ccagtctgta agaagtgcta tgagaaattt ccattggagc tgaagaaaag acttaagaaa     1080

ctagctgaga ccttaggaag gaaataagtt cctttatttt ttcttttcta tgcaagataa     1140

gagattacca acattacttg tcttgatcta cccatattta aagctatatc tcaaagcagt     1200

tgagagaaga ggacctatat gaatggtttt atgtcatttt tttaattaaa aaagaaaaat     1260

tcatataatc gtgtttaaaa cacaaatgaa gtcagtattt gcctttgtta acccttatcc     1320

atttgttgac atgtagactg tttacaaaaa aaaaacacat ggttaaatgt taaattttaa     1380

ttaaggcccc caaaaattaa atataacttt ttaaaatgaa aggagtcacc ttttacatga     1440

ctcaggtgaa aaaacagtat aaacattaat ttactttgtg ttcaaaagaa aattccaact     1500

gctgttgggg aaggacacag aaaagaaaaa taaccaccca agaaaaacaa aaacaagaaa     1560

aacaaatctt atacaatctt agtatattta tcaaactagt agctagaaag tgaatatgca     1620

cattactaag acaaaaaaca agtgtaattc agaactactt gatttttttt agttaaatgc     1680

aataattatt atgcttagtt ttataacctg ctctccttgt gaattcttcc ttcaaatgat     1740

tacttaacgc agtagtaata gctagctgta ggatgtcctt taaatttttg tgcaaaaaaa     1800

aatttatacc aggtatttgg aaatatactt tacaatattg gaaaatgaag tatttttaat     1860

gtattacagc aattatgttt ctaagcttaa tgttaagcat gtagtcttag aataggacat     1920

gaaattaaat tgtatgtagc ttggaatata ttgcttcaga aaactgaatg tgtatgtcgg     1980

tcatattgcc tttataacca tgctaatatc tatgctttat acatactcaa acttgccttg     2040

ccttaaaaac atacatacta catacttaaa tcaggaattc tagccatctc acagaatacc     2100

aactaaaact aagtgcattg agatctgaga ttggtaaacc cagattcatt taccacagct     2160

gtaattaagt ttttagaaac tattctcttt ttggggaaat ccattgaagt taatttctgt     2220

tatcttatta gaagaaaatg atgttgatat gtgtttcaga ttttccattt gaaatcttat     2280

aattaatttg atttatttac tgtaagtagg aggtataaat gacactctta aattggaagg     2340

aggggtgttt tagtgtctgt tttaggtcaa aattagtgat tctattttta tcaaaagttt     2400

tatcctgaag tttcaggacc actcttcctt aataaacttg ttaatggaaa gcgagcttta     2460

tgaacattta aaaatgttgc tgctgctttg ttgcttaaaa agaaagttgc caagagagac     2520

ttcttaggga aaatatttgg gttttttttc caaaaattgc tgaaatattg ttttgccatt     2580

tttaaaaagt ctcaggttat taccactctg ccattaaata tttgtatgcc tgcattttta     2640

aaaattctgt gcatgtactt tatggagtac attctatttt tgttttcaga taccctacaa     2700

ccaatttttt ttagtaatct tttagaattg aaattatcat aaatgatcga gaataatcat     2760

cacatagttt aagattgtat atgttgagta gtttaaaaca atctttgcat tttacagtaa     2820

gaatcaaagt cccttcagtg tgcctttgtc agctaatatg tgaccagcaa tgacaacctt     2880

gggagtattt attaaatatt atgctatgaa tataggcaac acagaacagg gtttgcagta     2940

tagcgtcttg atgctaaatt ctcatatacc tctacacgag aaatatggag gagaaaaaca     3000

agcatttaca tatattcttc gtcactttga agatgcatgg cctgaactcg actgcttgtg     3060

tttgtttaca tatcaggcat acccaggcat ctcctgcagc cagaggttcc attgctgtct     3120

ttgctcagtc ctcttttaaa atatgaatta gtggacaggc acggtgcctc acacctgtaa     3180

tcccagcact ttgggaggtc gaggcaggtg gatcacgagg tcaggagatc aagaccatcc     3240

tggctaccac tgaaacccca tctctactac aaaaaaatta gccgggcgtg gtggcgggca     3300

cctgcagtcc cagctactcg ggaggctgag gcaggagaat ggtgggaacc cgggaggcag     3360

agcttgcagt gagccaagat cacgccactg cactccagcc tgggcaacag agcaagactc     3420

tgtctcaaaa aaaataaata aataaattat gaatgagtat tttctagaaa ttcaacttgc     3480

taagcctgta atacttaagg gtagtttatc tagatacagt actttcttcc ctgataagta     3540

gtatcattgg agcccttagg tataggagaa gaggaagaag tttaaaaagt gtaagtgggc     3600

cgggcgtggt ggctcatgcc tgtaatccca gcactttggg aggccgaggg gggcggatca     3660

cgaggtcagg agatccagac tatcctggct aacaaggtga aaccccgtct ctactaaaaa     3720

tacaaaaaaa aacattagcc aggcgtggtg gcgggcgctt gtagtcccag ctactcggga     3780

ggctgaggta ggagaatggc ttgaacccag gaggcggagc ttgcagtgag ccgagattgc     3840

accactgcac tccagcctgg gcgacagagc aagactccgt ctcaaaaaaa aaaaaaaagt     3900

gtaagtggat taaaagagaa acttggtcta gttcataata tttttaatag ggctttccct     3960

ggctgctgga aaacttaggc cagtaagcat ctctttgttt aaagtcctac aagacaattt     4020

gaaataattc attgttcatg ccaaaattct aagtactgtt tttcttagca agtgtaacat     4080

aatcaggaac aatgggtaca agtaaaacat tctttggatg atattcaaag ccttattagc     4140

actgcacctg aataataggt cattttgcct cactcatttg ccaaagtagc catttctaag     4200

ttaaggaagt ttttagatag gctcatagcc ttgtatttcg ttttagattg taagctcaat     4260

ggcagggata ctatattggt aattatgttt tcatatagca accaccacag tatattcttg     4320

gtgcttaata aatgtttata attgttaaca ataaaaaaaa aaaaaaaaa                 4369


<210>  974
<211>  3715
<212>  DNA
<213>  homo sapiens

<400>  974
gacgtcatgt tcgccgggca ggcgaggaaa gaggacgcca tgattggttg gcgctggggc       60

ggcggacggt ggaagggcct ggcgagtcta ggttttacgc ctgtgctgga ctttctcctt      120

ccatgtttcc aggccgtggg gggctacaga gggcgagaag tcggctcagc ggaaacctgg      180

atttggttct aagccgtggg gttgagaagg ggtgaccgga agtgatcgtg ggactgaccg      240

gaagcgaggc ctggagggga aagagagagc gagacctggg agggaggggg cctccagcag      300

aaaggggcgg gggaaaaggt gcaaaagcag cgtgggagcg ccgggctggc ttcctgcggc      360

tgctgctggt ctgactggga agcagcaagc caccactacg aactctcaag aggagtggga      420

gtgcgggagt ccagagctgc ctctgggaag tctgcagtag ttgagcaaag gggtcctcac      480

gttcctgaga gctgggcagg ggggattttg gaacctgggg cagccaagaa cgagcagcca      540

agggtacggg agattagttg tgcacagagc agtgctggtc gggcttgggg gtggctggtg      600

ggcactgcgt gggaaacctt ggtttgtagt tttcttggtt tgcgttactc ctgttgggta      660

gaattaccct ccgcgccttt gtacaagaca cggtgtctcc tggggcaagg aaggagccag      720

gatggcctgg gctctgaagc tgcctctggc cgacgaagtg attgaatccg ggttggtgca      780

ggactttgat gctagcctgt ccgggatcgg ccaggaactg ggtgctggtg cctatagcat      840

gagtgatgtc cttgcattgc ccatttttaa gcaagaagag tcgagtttgc ctcctgataa      900

tgagaataaa atcctgcctt ttcaatatgt gctttgtgct gctacctctc cagcagtgaa      960

actccatgat gaaaccctaa cgtatctcaa tcaaggacag tcttatgaaa ttcgaatgct     1020

agacaatagg aaacttggag aacttccaga aattaatggc aaattggtga agagtatatt     1080

ccgtgtggtg ttccatgaca gaaggcttca gtacactgag catcagcagc tagagggctg     1140

gaggtggaac cgacctggag acagaattct tgacatagat atcccgatgt ctgtgggtat     1200

aatcgatcct agggctaatc caactcaact aaatacagtg gagttcctgt gggaccctgc     1260

aaagaggaca tctgtgttta ttcaggtgca ctgtattagc acagagttca ctatgaggaa     1320

acatggtgga gaaaaggggg tgccattccg agtacaaata gataccttca aggagaatga     1380

aaacggggaa tatactgagc acttacactc ggccagctgc cagatcaaag ttttcaagcc     1440

caaaggtgca gacagaaagc aaaaaacgga tagggaaaaa atggagaaac gaacacctca     1500

tgaaaaggag aaatatcagc cttcctatga gacaaccata ctcacagagt gttctccatg     1560

gcccgagatc acgtatgtca ataactcccc atcacctggc ttcaacagtt cccatagcag     1620

tttttctctt ggggaaggaa atggttcacc aaaccaccag ccagagccac cccctccagt     1680

cacagataac ctcttaccaa caaccacacc tcaggaagct cagcagtggt tgcatcgaaa     1740

tcgtttttct acattcacaa ggcttttcac aaacttctca ggggcagatt tattgaaatt     1800

aactagagat gatgtgatcc aaatctgtgg ccctgcagat ggaatcagac tttttaatgc     1860

attaaaaggc cggatggtgc gtccaaggtt aaccatttat gtttgtcagg aatcactgca     1920

gttgagggag cagcaacaac agcagcagca acagcagcag aagcatgagg atggagactc     1980

aaatggtact ttcttcgttt accatgctat ctatctagaa gaactaacag ctgttgaatt     2040

gacagaaaaa attgctcagc ttttcagcat ttccccttgc cagatcagcc agatttacaa     2100

gcaggggcca acaggaattc atgtgctcat cagtgatgag atgatacaga actttcagga     2160

agaagcatgt tttattctgg acacaatgaa agcagaaacc aatgatagct atcatatcat     2220

actgaagtag gagtgcggcg tttcgtgccc agtggctgct ccttccttca cctctgaaaa     2280

cggccctctt gaagggggat atgaatggag atttgaaggt ctgcaagaac ctgactcgtc     2340

tgactgtgtg tggaggagtc caggccatgg aggcagaatc ctggccctct gtgttggccc     2400

aagctcttgt ggtacacaca gattactgcc caatatgcag ttctgcagct gttttagtta     2460

aatttctgga ccttgttgtt gttaaatatc agtagaaact ctacataatt tagagtgtat     2520

gtagggcata atgatgatgg gaattgtgtg atgtttaaca ggaagatctt aaattttgtg     2580

atatggagcc ctgtaatttt tttcttatat aaaaatgggt atctatattc ataagactag     2640

gtcttcaatc tctttgtact ggtctcaaat gtactggtat ctctgctttt tgccacagtt     2700

tgtccctgaa aactttatca gtgaggagaa atacagaatt ttccttttgg ttcccctgta     2760

ataccacaac taatagtatt ttcagctaac atttattgac caggcagtgt gataaatttt     2820

ttgaatgacc atcttgttta accccctaat cacactatct gaagtaggtg ctatagtgac     2880

ccccaaccga agatgaggaa atggagacac acagtggcta agtagcttgc taggtgccag     2940

gagctggcag gcagtgatgc tgaaatccaa accaggcaat ctggccctcc ttattcaccc     3000

tctcatacca ccagtgctac ccattataac ctgtgttcac ttcgcttatt actgtggccc     3060

ttctggtgac tacaacataa cactgagtat gaactgagga attaaccact gaaagagaca     3120

aagcacacct aaataatgat gaacaaatca agacctacaa gaaatgaaca catagatgct     3180

ttttaagtgt cattagttat cggaatcaaa gaatttgagg tggtgacaac tggggattat     3240

ctgtaactcc ccaaatttac tgttcttgaa tgacattctc aaactattta ttaatgagtt     3300

agtctcatcc ctgctttctg tttcctctct ctgcatcttc tcttggcata ggaagttatt     3360

ttactcatgc tatgtttttt aatagaagct ttacaaaaaa agatgcattc ccttcctgtt     3420

cacactctta ccatgttttt gttcttcctt aagaatgatt gtgtgtgtgt gtgtgtgtgt     3480

gtgtaagtgt gtaagtgtaa catcatgggt tttctttctt cacttgtaaa gttttatcta     3540

gaaatacttt tacaggttat gttgaggtac acaaagataa tgttctaaga ttgtgtattg     3600

gatttggatt tgtgtgtgtg tgtgtgtgtg tgtgtgttta aagcatttga taaggtttaa     3660

atgtttttta tacagagatt tttgttcatt aaactcaatc tgcatcatgg tctaa          3715


<210>  975
<211>  3715
<212>  DNA
<213>  homo sapiens

<400>  975
gacgtcatgt tcgccgggca ggcgaggaaa gaggacgcca tgattggttg gcgctggggc       60

ggcggacggt ggaagggcct ggcgagtcta ggttttacgc ctgtgctgga ctttctcctt      120

ccatgtttcc aggccgtggg gggctacaga gggcgagaag tcggctcagc ggaaacctgg      180

atttggttct aagccgtggg gttgagaagg ggtgaccgga agtgatcgtg ggactgaccg      240

gaagcgaggc ctggagggga aagagagagc gagacctggg agggaggggg cctccagcag      300

aaaggggcgg gggaaaaggt gcaaaagcag cgtgggagcg ccgggctggc ttcctgcggc      360

tgctgctggt ctgactggga agcagcaagc caccactacg aactctcaag aggagtggga      420

gtgcgggagt ccagagctgc ctctgggaag tctgcagtag ttgagcaaag gggtcctcac      480

gttcctgaga gctgggcagg ggggattttg gaacctgggg cagccaagaa cgagcagcca      540

agggtacggg agattagttg tgcacagagc agtgctggtc gggcttgggg gtggctggtg      600

ggcactgcgt gggaaacctt ggtttgtagt tttcttggtt tgcgttactc ctgttgggta      660

gaattaccct ccgcgccttt gtacaagaca cggtgtctcc tggggcaagg aaggagccag      720

gatggcctgg gctctgaagc tgcctctggc cgacgaagtg attgaatccg ggttggtgca      780

ggactttgat gctagcctgt ccgggatcgg ccaggaactg ggtgctggtg cctatagcat      840

gagtgatgtc cttgcattgc ccatttttaa gcaagaagag tcgagtttgc ctcctgataa      900

tgagaataaa atcctgcctt ttcaatatgt gctttgtgct gctacctctc cagcagtgaa      960

actccatgat gaaaccctaa cgtatctcaa tcaaggacag tcttatgaaa ttcgaatgct     1020

agacaatagg aaacttggag aacttccaga aattaatggc aaattggtga agagtatatt     1080

ccgtgtggtg ttccatgaca gaaggcttca gtacactgag catcagcagc tagagggctg     1140

gaggtggaac cgacctggag acagaattct tgacatagat atcccgatgt ctgtgggtat     1200

aatcgatcct agggctaatc caactcaact aaatacagtg gagttcctgt gggaccctgc     1260

aaagaggaca tctgtgttta ttcaggtgca ctgtattagc acagagttca ctatgaggaa     1320

acatggtgga gaaaaggggg tgccattccg agtacaaata gataccttca aggagaatga     1380

aaacggggaa tatactgagc acttacactc ggccagctgc cagatcaaag ttttcaagcc     1440

caaaggtgca gacagaaagc aaaaaacgga tagggaaaaa atggagaaac gaacacctca     1500

tgaaaaggag aaatatcagc cttcctatga gacaaccata ctcacagagt gttctccatg     1560

gcccgagatc acgtatgtca ataactcccc atcacctggc ttcaacagtt cccatagcag     1620

tttttctctt ggggaaggaa atggttcacc aaaccaccag ccagagccac cccctccagt     1680

cacagataac ctcttaccaa caaccacacc tcaggaagct cagcagtggt tgcatcgaaa     1740

tcgtttttct acattcacaa ggcttttcac aaacttctca ggggcagatt tattgaaatt     1800

aactagagat gatgtgatcc aaatctgtgg ccctgcagat ggaatcagac tttttaatgc     1860

attaaaaggc cggatggtgc gtccaaggtt aaccatttat gtttgtcagg aatcactgca     1920

gttgagggag cagcaacaac agcagcagca acagcagcag aagcatgagg atggagactc     1980

aaatggtact ttcttcgttt accatgctat ctatctagaa gaactaacag ctgttgaatt     2040

gacagaaaaa attgctcagc ttttcagcat ttccccttgc cagatcagcc agatttacaa     2100

gcaggggcca acaggaattc atgtgctcat cagtgatgag atgatacaga actttcagga     2160

agaagcatgt tttattctgg acacaatgaa agcagaaacc aatgatagct atcatatcat     2220

actgaagtag gagtgcggcg tttcgtgccc agtggctgct ccttccttca cctctgaaaa     2280

cggccctctt gaagggggat atgaatggag atttgaaggt ctgcaagaac ctgactcgtc     2340

tgactgtgtg tggaggagtc caggccatgg aggcagaatc ctggccctct gtgttggccc     2400

aagctcttgt ggtacacaca gattactgcc caatatgcag ttctgcagct gttttagtta     2460

aatttctgga ccttgttgtt gttaaatatc agtagaaact ctacataatt tagagtgtat     2520

gtagggcata atgatgatgg gaattgtgtg atgtttaaca ggaagatctt aaattttgtg     2580

atatggagcc ctgtaatttt tttcttatat aaaaatgggt atctatattc ataagactag     2640

gtcttcaatc tctttgtact ggtctcaaat gtactggtat ctctgctttt tgccacagtt     2700

tgtccctgaa aactttatca gtgaggagaa atacagaatt ttccttttgg ttcccctgta     2760

ataccacaac taatagtatt ttcagctaac atttattgac caggcagtgt gataaatttt     2820

ttgaatgacc atcttgttta accccctaat cacactatct gaagtaggtg ctatagtgac     2880

ccccaaccga agatgaggaa atggagacac acagtggcta agtagcttgc taggtgccag     2940

gagctggcag gcagtgatgc tgaaatccaa accaggcaat ctggccctcc ttattcaccc     3000

tctcatacca ccagtgctac ccattataac ctgtgttcac ttcgcttatt actgtggccc     3060

ttctggtgac tacaacataa cactgagtat gaactgagga attaaccact gaaagagaca     3120

aagcacacct aaataatgat gaacaaatca agacctacaa gaaatgaaca catagatgct     3180

ttttaagtgt cattagttat cggaatcaaa gaatttgagg tggtgacaac tggggattat     3240

ctgtaactcc ccaaatttac tgttcttgaa tgacattctc aaactattta ttaatgagtt     3300

agtctcatcc ctgctttctg tttcctctct ctgcatcttc tcttggcata ggaagttatt     3360

ttactcatgc tatgtttttt aatagaagct ttacaaaaaa agatgcattc ccttcctgtt     3420

cacactctta ccatgttttt gttcttcctt aagaatgatt gtgtgtgtgt gtgtgtgtgt     3480

gtgtaagtgt gtaagtgtaa catcatgggt tttctttctt cacttgtaaa gttttatcta     3540

gaaatacttt tacaggttat gttgaggtac acaaagataa tgttctaaga ttgtgtattg     3600

gatttggatt tgtgtgtgtg tgtgtgtgtg tgtgtgttta aagcatttga taaggtttaa     3660

atgtttttta tacagagatt tttgttcatt aaactcaatc tgcatcatgg tctaa          3715


<210>  976
<211>  4758
<212>  DNA
<213>  homo sapiens

<400>  976
cccgagccga gcccgccgcg gtcacagcca cccgcgggaa gctcgtggcc gggaccccga       60

ggcgggagcg cgggctgggc cgggctgggc tacgcgcacg ggctcggccg ccgcccctgc      120

cggttgcata ccctgtcctg agggcgcggc acggagtgca tgcgggccgc tgccatgacg      180

accgccatct tggagcgcct gagcaccctg tcggtcagcg ggcagcagct gcgccgcctg      240

cccaagatcc tggaggatgg gcttcccaag atgccttgca ctgtcccaga aacggatgtg      300

ccccagctct tccgggagcc ttacatccgc accggctacc gccccacggg gcacgagtgg      360

cgctactact tcttcagcct ctttcagaaa cacaacgagg tggtcaacgt ctggacccat      420

ttactggcag ccctggccgt cctcttgcga ttctgggcct ttgccgaggc tgaggccttg      480

ccatgggcgt ctacccactc cctgcctctg ctcctcttca tcctgtcgtc aatcacttac      540

ctcacctgca gccttctggc ccacctgctg cagtccaagt cagagctctc ccactacacc      600

ttctactttg tggactatgt tggcgtgagc gtttaccaat atggcagtgc tttggctcat      660

ttcttctaca gctctgacca ggcctggtat gaccggttct ggcttttctt cttgccagca      720

gctgccttct gtggctggtt atcttgtgct ggctgttgct atgccaaata tcgttaccgg      780

aggccttatc cagtcatgag gaagatctgt caagtggtgc cagcaggtct ggcttttatc      840

ctagacatca gccctgtggc acaccgtgtg gcgctctgtc acctggctgg ctgccaggag      900

caagcagcct ggtaccacac cctccagatc ctcttcttcc tggttagcgc ttatttcttc      960

tcctgccccg tgcctgagaa gtacttcccg ggttcctgtg acatcgtggg ccatgggcat     1020

cagatcttcc atgcatttct gtccatctgt acgctctccc agctggaggc catcctcctg     1080

gactaccagg ggcggcagga gatcttcctg cagcgccatg gacccctatc tgtccacatg     1140

gcctgcctct ccttcttctt cctggctgcc tgcagtgctg ccaccgcagc ccttctgagg     1200

cacaaagtca aggccagact gaccaagaaa gattcctgag gctggcaagt ggggcaacgt     1260

gtggaggaag cccctcataa tttggagaaa acttgataca atagaagctg acttttaagg     1320

cattggcttt taaattaata catatatcca aggatatgtt atagctgcag tgtttgaaag     1380

ccaaaggatt taagagtttt gttgttgtta ataaaaggaa tactcctttt ccttttggat     1440

catagcttaa caaggcacag gaagggaagg gatcttgact aagattcatg agacattgaa     1500

ttaaggagaa tcatcttcat gcctgaaaat ttagcaaaat tccgactatg gcctccaggg     1560

gcaattccta aaagctgaat ggataataaa attggactgg aaagtaagta ggtggctggt     1620

cctcaccctg ttggaatggc tatcctacta tgctgttctt tggtaatgga ataaattgac     1680

ccaaggaccg aatttcattt ggatttcaaa ttgtccagag tggaaaagcc ttcaagatga     1740

catgatgaat tactcagttc atctgatttc tggtccctcc tttctcgaca actataatac     1800

taaccctttt ctcaggataa ctgtctacac ctggcagttt tctctgacgt gctgttcact     1860

cacatcccta ccttgcatgg taatataaag gactaggaag cagtcatact tccaggaaat     1920

gcttggattc atgtggacat tcaggaagct tattctcata taatactaat ctaaacagta     1980

ctagaaatta cagtgccaag agccaccagg aggcccagcc aataagcata gatactatat     2040

ggtatcatgg gacccatcta ttttttacca gtggactaca ggattacttg agagttatca     2100

gggctgccta acagaccagg agatctgggg gttgcaccag ggaatcgcca tatttgacca     2160

gcatgtttta aaagctcttg gtaggattag ttggttctaa ggatccctct agggacctca     2220

ttatttcaag aggaacccaa agtccagcct cctacataga tgctgcccca cgaaggaccc     2280

acaaaactaa cctagttcag ggttctcagg caggcagttc tgcttcagct tagagcagaa     2340

cccataaaat actcaagtac tgggataggc aagcatgtgt gtttactgtg gattggtccc     2400

tgaaggctcc tttgggtgag aacatgtgaa ccaggcaccc tggtttgttt ggagcattgc     2460

tgcccagaag cttctatggg ataggtggtg cttgggattg atgtgttgtg gccatgcagc     2520

cctccctgag gattgacttc tgcactaatc cagtgaagga ggctgtgtca aaagaagggc     2580

tcagaagccc tcttttcaga ggcaatgatt cctgtcagta tgaggtccct tagttactaa     2640

aaagggacat gatttaactc cagtttgatg aacctcctcc gagtttactt tattgtcttc     2700

aaatcttttg ttttcttcct ttttgtgaga tttgtgggtt ttgtgcctta taaatggaaa     2760

tgtatgaaca caatatatgc tcatgtagaa ttttctgttc tgggttattg ggataagaaa     2820

aaatatatat tgctcttcaa ctagtgaatg aaagaaactt cagaaagcta gaattgctta     2880

tcaatcaaaa gactttctca atctattttg gccacaaaca aacatattca actgaagctt     2940

tccaataatc tttatatcaa gaaagcatgc gtcttgtcag ctacattgtt ttcttagatg     3000

gatttctcct gttaatcctc aaatatctga acttctgtgt tacccaagtg tcttatacaa     3060

gcttctggtg tctaggacaa atttatggca aataaaatta gcaaaactga actgggttga     3120

actgaacaag aggatggggg aattgtgcaa atacgttgtt agtagaaggt caatttaaaa     3180

tagggactag aaattatttg aagttttctt tattacggat tcaaagactt attttgaaag     3240

ttggaaggag aagggaggga agagagcaga agggaagaag gtgtaagtca agctcttgaa     3300

tataactggt ggtattgtgg gcagagatct ttagttcaaa tccacgtatt ttttaaaaga     3360

gagaaccgga ggtagagcaa tgatcagatg ggtgcacaga ccagtgccaa tctgaacatt     3420

gttaatggcc tgtgacatga tgagcacagg aacaggcatg aagatattgc catacaattt     3480

taatttatac aagtattggc ccctcaagtg gttggaaatt ttttttttaa tctctttttc     3540

tgagacaggg tcttactctg tcgcccaggc tggagtgcag tgatgcaatc acggctcact     3600

gcagcctcga cctccccagc tcaagcaatc ctcccacctc agcctcctaa gtacctggta     3660

ctacaggcgc gtgccaccac acctggctaa tttttgcatt ttttgtagag acagggtttt     3720

gccacgttgc ttaggctggt cttgaactcc tgaactcaag tgatccgccc acctcagcct     3780

cccaaagtgt tgggattaca gacattagcc atcacgcctg ccctagaaac agttttttaa     3840

taggagatat ttgagaggca ttgaggtagg agactctatg acatgccctc agaatatcag     3900

aatcttctta gaaataaact aggaaatgca gatgttttta actactcaga cttttgagga     3960

attaatcctt ttaaaacatt tttgttaaag ttagtgtatc agtaagaaac agacctagtt     4020

taaaaggaat aatcaacaat tttataaagg agatggctta ttcaaccata gcccctccaa     4080

catatctact ggaaattctg ctggttaact ttatctctct ctctcttaat ttagactttc     4140

aacctatgaa aatgtaaata cctttgaaaa aactaaacta tcagtcattt acatcctctc     4200

atgaatgaaa tgcagtgtag ggagaggaga tggcaggaca cagcaaacag gacacatttg     4260

cctgcttctc tcttgcctaa ttcttcctga cctgtattta ctgatgctta ataatacttg     4320

taagactcta ggggttcatt tcccatttca gcggaaagta cttcactcaa caacaatatt     4380

ctcaagagtc ttctactgga agctagaaag aaataggaat ttaagtccat agaatgaagg     4440

tagttattcc tgcctgtgtt gcccacctgt tcacaaaaag tacctttatg cttgaaaaca     4500

ttaggttctt tggttactgc actgtagttt caaatggatc ctccagatgg cattcatgtc     4560

ttactcagaa agggcactgc cattgtcccc aaggcttctg tctactaatt ctattggtct     4620

tgtgttttgc ttgcttggca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa atggagctat     4680

tttctgtcta tataaatcta cttatatgaa taaccattaa agtgattttg tatatgcaaa     4740

aaaaaaaaaa aaaaaaaa                                                   4758


<210>  977
<211>  6960
<212>  DNA
<213>  homo sapiens

<400>  977
acacagtact ctcagcttgt tggtggaagc ccctcatctg ccttcattct gaaggcaggg       60

cccggcagag gaaggatcag agggtcgcgg ccggagggtc ccggccggtg gggccaactc      120

agagggagag gaaagggcta gagacacgaa gaacgcaaac catcaaattt agaagaaaaa      180

gccctttgac tttttccccc tctccctccc caatggctgt gtagcaaaca tccctggcga      240

taccttggaa aggacgaagt tggtctgcag tcgcaatttc gtgggttgag ttcacagttg      300

tgagtgcggg gctcggagat ggagccgtgg tcctctaggt ggaaaacgaa acggtggctc      360

tgggatttca ccgtaacaac cctcgcattg accttcctct tccaagctag agaggtcaga      420

ggagctgctc cagttgatgt actaaaagca ctagattttc acaattctcc agagggaata      480

tcaaaaacaa cgggattttg cacaaacaga aagaattcta aaggctcaga tactgcttac      540

agagtttcaa agcaagcaca actcagtgcc ccaacaaaac agttatttcc aggtggaact      600

ttcccagaag acttttcaat actatttaca gtaaaaccaa aaaaaggaat tcagtctttc      660

cttttatcta tatataatga gcatggtatt cagcaaattg gtgttgaggt tgggagatca      720

cctgtttttc tgtttgaaga ccacactgga aaacctgccc cagaagacta tcccctcttc      780

agaactgtta acatcgctga cgggaagtgg catcgggtag caatcagcgt ggagaagaaa      840

actgtgacaa tgattgttga ttgtaagaag aaaaccacga aaccacttga tagaagtgag      900

agagcaattg ttgataccaa tggaatcacg gtttttggaa caaggatttt ggatgaagaa      960

gtttttgagg gggacattca gcagtttttg atcacaggtg atcccaaggc agcatatgac     1020

tactgtgagc attatagtcc agactgtgac tcttcagcac ccaaggctgc tcaagctcag     1080

gaacctcaga tagatgagta tgcaccagag gatataatcg aatatgacta tgagtatggg     1140

gaagcagagt ataaagaggc tgaaagtgta acagagggac ccactgtaac tgaggagaca     1200

atagcacaga cggagataaa tggccatggt gcatatggag agaaaggaca gaaaggagaa     1260

ccagcagtgg ttgagcctgg tatgcttgtc gaaggaccac caggaccagc aggacctgca     1320

ggtattatgg gtcctccagg tctacaaggc cccactggac cccctggtga ccctggcgat     1380

aggggccccc caggacgtcc tggcttacca ggggctgatg gtctacctgg tcctcctggt     1440

actatgttga tgttaccgtt ccgttatggt ggtgatggtt ccaaaggacc aaccatctct     1500

gctcaggaag ctcaggctca agctattctt cagcaggctc ggattgctct gagaggccca     1560

cctggcccaa tgggtctaac tggaagacca ggtcctgtgg gggggcctgg ttcatctggg     1620

gccaaaggtg agagtggtga tccaggtcct cagggccctc gaggcgtcca gggtccccct     1680

ggtccaacgg gaaaacctgg aaaaaggggt cgtccaggtg cagatggagg aagaggaatg     1740

ccaggagaac ctggggcaaa gggagatcga gggtttgatg gacttccggg tctgccaggt     1800

gacaaaggtc acaggggtga acgaggtcct caaggtcctc caggtcctcc tggtgatgat     1860

ggaatgaggg gagaagatgg agaaattgga ccaagaggtc ttccaggtga agctggccca     1920

cgaggtttgc tgggtccaag gggaactcca ggagctccag ggcagcctgg tatggcaggt     1980

gtagatggcc ccccaggacc aaaagggaac atgggtcccc aaggggagcc tgggcctcca     2040

ggtcaacaag ggaatccagg acctcagggt cttcctggtc cacaaggtcc aattggtcct     2100

cctggtgaaa aaggaccaca aggaaaacca ggacttgctg gacttcctgg tgctgatggg     2160

cctcctggtc atcctgggaa agaaggccag tctggagaaa agggggctct gggtccccct     2220

ggtccacaag gtcctattgg atacccgggc ccccggggag taaagggagc agatggtgtc     2280

agaggtctca agggatctaa aggtgaaaag ggtgaagatg gttttccagg attcaaaggt     2340

gacatgggtc taaaaggtga cagaggagaa gttggtcaaa ttggcccaag aggggaagat     2400

ggccctgaag gacccaaagg tcgagcaggc ccaactggag acccaggtcc ttcaggtcaa     2460

gcaggagaaa agggaaaact tggagttcca ggattaccag gatatccagg aagacaaggt     2520

ccaaagggtt ccactggatt ccctgggttt ccaggtgcca atggagagaa aggtgcacgg     2580

ggagtagctg gcaaaccagg ccctcggggt cagcgtggtc caacgggtcc tcgaggttca     2640

agaggtgcaa gaggtcccac tgggaaacct gggccaaagg gcacttcagg tggcgatggc     2700

cctcctggcc ctccaggtga aagaggtcct caaggacctc agggtccagt tggattccct     2760

ggaccaaaag gccctcctgg accacctggg aaggatgggc tgccaggaca ccctgggcaa     2820

cgtggggaga ctggatttca aggcaagacc ggccctcctg ggccaggggg agtggttgga     2880

ccacagggac caaccggtga gactggtcca ataggggaac gtgggcatcc tggccctcct     2940

ggccctcctg gtgagcaagg tcttcctggt gctgcaggaa aagaaggtgc aaagggtgat     3000

ccaggtcctc aaggtatctc agggaaagat ggaccagcag gattacgtgg tttcccaggg     3060

gaaagaggtc ttcctggagc tcagggtgca cctggactga aaggagggga aggtccccag     3120

ggcccaccag gtccagttgg ctcaccagga gaacgtgggt cagcaggtac agctggccca     3180

attggtttac cagggcgccc gggacctcag ggtcctcctg gtccagctgg agagaaaggt     3240

gctcctggag aaaaaggtcc ccaagggcct gcagggagag atggagttca aggtcctgtt     3300

ggtctcccag ggccagctgg tcctgccggc tcccctgggg aagacggaga caagggtgaa     3360

attggtgagc cgggacaaaa aggcagcaag ggtgacaagg gagaaaatgg ccctcccggt     3420

cccccaggtc ttcaaggacc agttggtgcc cctggaattg ctggaggtga tggtgaacca     3480

ggtcctagag gacagcaggg gatgtttggg caaaaaggtg atgagggtgc cagaggcttc     3540

cctggacctc ctggtccaat aggtcttcag ggtctgccag gcccacctgg tgaaaaaggt     3600

gaaaatgggg atgttggtcc catggggcca cctggtcctc caggcccaag aggccctcaa     3660

ggtcccaatg gagctgatgg accacaagga cccccagggt ctgttggttc agttggtggt     3720

gttggagaaa agggtgaacc tggagaagca gggaacccag ggcctcctgg ggaagcaggt     3780

gtaggcggtc ccaaaggaga aagaggagag aaaggggaag ctggtccacc tggagctgct     3840

ggacctccag gtgccaaggg gccaccaggt gatgatggcc ctaagggtaa cccgggtcct     3900

gttggttttc ctggagatcc tggtcctcct ggggaacctg gccctgcagg tcaagatggt     3960

gttggtggtg acaagggtga agatggagat cctggtcaac cgggtcctcc tggcccatct     4020

ggtgaggctg gcccaccagg tcctcctgga aaacgaggtc ctcctggagc tgcaggtgca     4080

gagggaagac aaggtgaaaa aggtgctaag ggggaagcag gtgcagaagg tcctcctgga     4140

aaaaccggcc cagtcggtcc tcagggacct gcaggaaagc ctggtccaga aggtcttcgg     4200

ggcatccctg gtcctgtggg agaacaaggt ctccctggag ctgcaggcca agatggacca     4260

cctggtccta tgggacctcc tggcttacct ggtctcaaag gtgaccctgg ctccaagggt     4320

gaaaagggac atcctggttt aattggcctg attggtcctc caggagaaca aggggaaaaa     4380

ggtgaccgag ggctccctgg aactcaagga tctccaggag caaaagggga tgggggaatt     4440

cctggtcctg ctggtccctt aggtccacct ggtcctccag gtttaccagg tcctcaaggc     4500

ccaaagggta acaaaggctc tactggaccc gctggccaga aaggtgacag tggtcttcca     4560

gggcctcctg ggtctccagg tccacctggt gaagtcattc agcctttacc aatcttgtcc     4620

tccaaaaaaa cgagaagaca tactgaaggc atgcaagcag atgcagatga taatattctt     4680

gattactcgg atggaatgga agaaatattt ggttccctca attccctgaa acaagacatt     4740

gagcatatga aatttccaat gggtactcag accaatccag cccgaacttg taaagacctg     4800

caactcagcc atcctgactt cccagatggt gaatattgga ttgatcctaa ccaaggttgc     4860

tcaggagatt ccttcaaagt ttactgtaat ttcacatctg gtggtgagac ttgcatttat     4920

ccagacaaaa aatctgaggg agtaagaatt tcatcatggc caaaggagaa accaggaagt     4980

tggtttagtg aatttaagag gggaaaactg ctttcatact tagatgttga aggaaattcc     5040

atcaatatgg tgcaaatgac attcctgaaa cttctgactg cctctgctcg gcaaaatttc     5100

acctaccact gtcatcagtc agcagcctgg tatgatgtgt catcaggaag ttatgacaaa     5160

gcacttcgct tcctgggatc aaatgatgag gagatgtcct atgacaataa tccttttatc     5220

aaaacactgt atgatggttg tgcgtccaga aaaggctatg aaaagactgt cattgaaatc     5280

aatacaccaa aaattgatca agtacctatt gttgatgtca tgatcaatga ctttggtgat     5340

cagaatcaga agttcggatt tgaagttggt cctgtttgtt ttcttggcta agattaagac     5400

aaagaacata tcaaatcaac agaaaatata ccttggtgcc accaacccat tttgtgccac     5460

atgcaagttt tgaataagga tggtatagaa aacaacgctg catatacagg taccatttag     5520

gaaataccga tgcctttgtg ggggcagaat cacatggcaa aagctttgaa aatcataaag     5580

atataagttg gtgtggctaa gatggaaaca gggctgattc ttgattccca attctcaact     5640

ctccttttcc tatttgaatt tctttggtgc tgtagaaaac aaaaaaagaa aaatatatat     5700

tcataaaaaa tatggtgctc attctcatcc atccaggatg tactaaaaca gtgtgtttaa     5760

taaattgtaa ttattttgtg tacagttcta tactgttatc tgtgtccatt tccaaaactt     5820

gcacgtgtcc ctgaattcca tctgactcta attttatgag aattgcagaa ctctgatggc     5880

aataaatata tgtattatga aaaaataaag ttgtaatttc tgatgactct aagtcccttt     5940

ctttggttaa taataaaatg cctttgtata tattgatgtt gaagagttca attatttgat     6000

gtcgccaaca aaattctcag agggcaaaaa tctggaagac ttttggaagc acactctgat     6060

caactcttct ctgccgacag tcattttgct gaatttcagc caaaaatatt atgcattttg     6120

atgctttatt caaggctata cctcaaactt tttcttctca gaatccagga tttcacagga     6180

tacttgtata tatggaaaac aagcaagttt atatttttgg acagggaaat gtgtgtaaga     6240

aagtatatta acaaatcaat gcctccgtca agcaaacaat catatgtata ctttttttct     6300

acgttatctc atctccttgt tttcagtgtg cttcaataat gcaggttaat attaaagatg     6360

gaaattaagc aattatttat gaatttgtgc aatgttagat tttcttatca atcaagttct     6420

tgaatttgat tctaagttgc atattataac agtctcgaaa attattttac ttgcccaaca     6480

aatattactt ttttcctttc aagataattt tataaatcat ttgacctacc taattgctaa     6540

atgaataaca tatggtggac tgttattaag agtatttgtt ttaagtcatt caggaaaatc     6600

taaacttttt tttccactaa ggtatttact ttaaggtagc ttgaaatagc aatacaattt     6660

aaaaattaaa aactgaattt tgtatctatt ttaagtaata tatgtaagac ttgaaaataa     6720

atgttttatt tcttatataa agtgttaaat taattgatac cagatttcac tggaacagtt     6780

tcaactgata atttatgaca aaagaacata cctgtaatat tgaaattaaa aagtgaaatt     6840

tgtcataaag aatttctttt atttttgaaa tcgagtttgt aaatgtcctt ttaagaaggg     6900

agatatgaat ccaataaata aactcaagtc ttggctacct ggaaaaaaaa aaaaaaaaaa     6960


<210>  978
<211>  7327
<212>  DNA
<213>  homo sapiens

<400>  978
acacagtact ctcagcttgt tggtggaagc ccctcatctg ccttcattct gaaggcaggg       60

cccggcagag gaaggatcag agggtcgcgg ccggagggtc ccggccggtg gggccaactc      120

agagggagag gaaagggcta gagacacgaa gaacgcaaac catcaaattt agaagaaaaa      180

gccctttgac tttttccccc tctccctccc caatggctgt gtagcaaaca tccctggcga      240

taccttggaa aggacgaagt tggtctgcag tcgcaatttc gtgggttgag ttcacagttg      300

tgagtgcggg gctcggagat ggagccgtgg tcctctaggt ggaaaacgaa acggtggctc      360

tgggatttca ccgtaacaac cctcgcattg accttcctct tccaagctag agaggtcaga      420

ggagctgctc cagttgatgt actaaaagca ctagattttc acaattctcc agagggaata      480

tcaaaaacaa cgggattttg cacaaacaga aagaattcta aaggctcaga tactgcttac      540

agagtttcaa agcaagcaca actcagtgcc ccaacaaaac agttatttcc aggtggaact      600

ttcccagaag acttttcaat actatttaca gtaaaaccaa aaaaaggaat tcagtctttc      660

cttttatcta tatataatga gcatggtatt cagcaaattg gtgttgaggt tgggagatca      720

cctgtttttc tgtttgaaga ccacactgga aaacctgccc cagaagacta tcccctcttc      780

agaactgtta acatcgctga cgggaagtgg catcgggtag caatcagcgt ggagaagaaa      840

actgtgacaa tgattgttga ttgtaagaag aaaaccacga aaccacttga tagaagtgag      900

agagcaattg ttgataccaa tggaatcacg gtttttggaa caaggatttt ggatgaagaa      960

gtttttgagg gggacattca gcagtttttg atcacaggtg atcccaaggc agcatatgac     1020

tactgtgagc attatagtcc agactgtgac tcttcagcac ccaaggctgc tcaagctcag     1080

gaacctcaga tagatgagaa aaagaaatcc aatttcaaaa agaagatgag gacagtggct     1140

actaaatcaa aggaaaaatc caaaaagttt acacccccca aatctgaaaa attttcatcc     1200

aagaagaaga aaagttatca agcatcagca aaagccaaac taggggtaaa ggcaaacatc     1260

gttgatgatt ttcaagaata caactatgga acaatggaaa gttaccagac agaagctcct     1320

aggcatgttt ctgggacaaa tgagccaaat ccagttgaag aaatatttac tgaagaatat     1380

ctaacgggag aggattatga ttcccagagg aaaaattctg aggatacact atatgaaaac     1440

aaagaaatag acggcaggga ttctgatctt ctggtagatg gagatttagg cgaatatgat     1500

ttttatgaat ataaagaata tgaagataaa ccaacaagcc cccctaatga agaatttggt     1560

ccaggtgtac cagcagaaac tgatattaca gaaacaagca taaatggcca tggtgcatat     1620

ggagagaaag gacagaaagg agaaccagca gtggttgagc ctggtatgct tgtcgaagga     1680

ccaccaggac cagcaggacc tgcaggtatt atgggtcctc caggtctaca aggccccact     1740

ggaccccctg gtgaccctgg cgataggggc cccccaggac gtcctggctt accaggggct     1800

gatggtctac ctggtcctcc tggtactatg ttgatgttac cgttccgtta tggtggtgat     1860

ggttccaaag gaccaaccat ctctgctcag gaagctcagg ctcaagctat tcttcagcag     1920

gctcggattg ctctgagagg cccacctggc ccaatgggtc taactggaag accaggtcct     1980

gtgggggggc ctggttcatc tggggccaaa ggtgagagtg gtgatccagg tcctcagggc     2040

cctcgaggcg tccagggtcc ccctggtcca acgggaaaac ctggaaaaag gggtcgtcca     2100

ggtgcagatg gaggaagagg aatgccagga gaacctgggg caaagggaga tcgagggttt     2160

gatggacttc cgggtctgcc aggtgacaaa ggtcacaggg gtgaacgagg tcctcaaggt     2220

cctccaggtc ctcctggtga tgatggaatg aggggagaag atggagaaat tggaccaaga     2280

ggtcttccag gtgaagctgg cccacgaggt ttgctgggtc caaggggaac tccaggagct     2340

ccagggcagc ctggtatggc aggtgtagat ggccccccag gaccaaaagg gaacatgggt     2400

ccccaagggg agcctgggcc tccaggtcaa caagggaatc caggacctca gggtcttcct     2460

ggtccacaag gtccaattgg tcctcctggt gaaaaaggac cacaaggaaa accaggactt     2520

gctggacttc ctggtgctga tgggcctcct ggtcatcctg ggaaagaagg ccagtctgga     2580

gaaaaggggg ctctgggtcc ccctggtcca caaggtccta ttggataccc gggcccccgg     2640

ggagtaaagg gagcagatgg tgtcagaggt ctcaagggat ctaaaggtga aaagggtgaa     2700

gatggttttc caggattcaa aggtgacatg ggtctaaaag gtgacagagg agaagttggt     2760

caaattggcc caagagggga agatggccct gaaggaccca aaggtcgagc aggcccaact     2820

ggagacccag gtccttcagg tcaagcagga gaaaagggaa aacttggagt tccaggatta     2880

ccaggatatc caggaagaca aggtccaaag ggttccactg gattccctgg gtttccaggt     2940

gccaatggag agaaaggtgc acggggagta gctggcaaac caggccctcg gggtcagcgt     3000

ggtccaacgg gtcctcgagg ttcaagaggt gcaagaggtc ccactgggaa acctgggcca     3060

aagggcactt caggtggcga tggccctcct ggccctccag gtgaaagagg tcctcaagga     3120

cctcagggtc cagttggatt ccctggacca aaaggccctc ctggaccacc tgggaaggat     3180

gggctgccag gacaccctgg gcaacgtggg gagactggat ttcaaggcaa gaccggccct     3240

cctgggccag ggggagtggt tggaccacag ggaccaaccg gtgagactgg tccaataggg     3300

gaacgtgggc atcctggccc tcctggccct cctggtgagc aaggtcttcc tggtgctgca     3360

ggaaaagaag gtgcaaaggg tgatccaggt cctcaaggta tctcagggaa agatggacca     3420

gcaggattac gtggtttccc aggggaaaga ggtcttcctg gagctcaggg tgcacctgga     3480

ctgaaaggag gggaaggtcc ccagggccca ccaggtccag ttggctcacc aggagaacgt     3540

gggtcagcag gtacagctgg cccaattggt ttaccagggc gcccgggacc tcagggtcct     3600

cctggtccag ctggagagaa aggtgctcct ggagaaaaag gtccccaagg gcctgcaggg     3660

agagatggag ttcaaggtcc tgttggtctc ccagggccag ctggtcctgc cggctcccct     3720

ggggaagacg gagacaaggg tgaaattggt gagccgggac aaaaaggcag caagggtgac     3780

aagggagaaa atggccctcc cggtccccca ggtcttcaag gaccagttgg tgcccctgga     3840

attgctggag gtgatggtga accaggtcct agaggacagc aggggatgtt tgggcaaaaa     3900

ggtgatgagg gtgccagagg cttccctgga cctcctggtc caataggtct tcagggtctg     3960

ccaggcccac ctggtgaaaa aggtgaaaat ggggatgttg gtcccatggg gccacctggt     4020

cctccaggcc caagaggccc tcaaggtccc aatggagctg atggaccaca aggaccccca     4080

gggtctgttg gttcagttgg tggtgttgga gaaaagggtg aacctggaga agcagggaac     4140

ccagggcctc ctggggaagc aggtgtaggc ggtcccaaag gagaaagagg agagaaaggg     4200

gaagctggtc cacctggagc tgctggacct ccaggtgcca aggggccacc aggtgatgat     4260

ggccctaagg gtaacccggg tcctgttggt tttcctggag atcctggtcc tcctggggaa     4320

cctggccctg caggtcaaga tggtgttggt ggtgacaagg gtgaagatgg agatcctggt     4380

caaccgggtc ctcctggccc atctggtgag gctggcccac caggtcctcc tggaaaacga     4440

ggtcctcctg gagctgcagg tgcagaggga agacaaggtg aaaaaggtgc taagggggaa     4500

gcaggtgcag aaggtcctcc tggaaaaacc ggcccagtcg gtcctcaggg acctgcagga     4560

aagcctggtc cagaaggtct tcggggcatc cctggtcctg tgggagaaca aggtctccct     4620

ggagctgcag gccaagatgg accacctggt cctatgggac ctcctggctt acctggtctc     4680

aaaggtgacc ctggctccaa gggtgaaaag ggacatcctg gtttaattgg cctgattggt     4740

cctccaggag aacaagggga aaaaggtgac cgagggctcc ctggaactca aggatctcca     4800

ggagcaaaag gggatggggg aattcctggt cctgctggtc ccttaggtcc acctggtcct     4860

ccaggtttac caggtcctca aggcccaaag ggtaacaaag gctctactgg acccgctggc     4920

cagaaaggtg acagtggtct tccagggcct cctgggtctc caggtccacc tggtgaagtc     4980

attcagcctt taccaatctt gtcctccaaa aaaacgagaa gacatactga aggcatgcaa     5040

gcagatgcag atgataatat tcttgattac tcggatggaa tggaagaaat atttggttcc     5100

ctcaattccc tgaaacaaga cattgagcat atgaaatttc caatgggtac tcagaccaat     5160

ccagcccgaa cttgtaaaga cctgcaactc agccatcctg acttcccaga tggtgaatat     5220

tggattgatc ctaaccaagg ttgctcagga gattccttca aagtttactg taatttcaca     5280

tctggtggtg agacttgcat ttatccagac aaaaaatctg agggagtaag aatttcatca     5340

tggccaaagg agaaaccagg aagttggttt agtgaattta agaggggaaa actgctttca     5400

tacttagatg ttgaaggaaa ttccatcaat atggtgcaaa tgacattcct gaaacttctg     5460

actgcctctg ctcggcaaaa tttcacctac cactgtcatc agtcagcagc ctggtatgat     5520

gtgtcatcag gaagttatga caaagcactt cgcttcctgg gatcaaatga tgaggagatg     5580

tcctatgaca ataatccttt tatcaaaaca ctgtatgatg gttgtgcgtc cagaaaaggc     5640

tatgaaaaga ctgtcattga aatcaataca ccaaaaattg atcaagtacc tattgttgat     5700

gtcatgatca atgactttgg tgatcagaat cagaagttcg gatttgaagt tggtcctgtt     5760

tgttttcttg gctaagatta agacaaagaa catatcaaat caacagaaaa tataccttgg     5820

tgccaccaac ccattttgtg ccacatgcaa gttttgaata aggatggtat agaaaacaac     5880

gctgcatata caggtaccat ttaggaaata ccgatgcctt tgtgggggca gaatcacatg     5940

gcaaaagctt tgaaaatcat aaagatataa gttggtgtgg ctaagatgga aacagggctg     6000

attcttgatt cccaattctc aactctcctt ttcctatttg aatttctttg gtgctgtaga     6060

aaacaaaaaa agaaaaatat atattcataa aaaatatggt gctcattctc atccatccag     6120

gatgtactaa aacagtgtgt ttaataaatt gtaattattt tgtgtacagt tctatactgt     6180

tatctgtgtc catttccaaa acttgcacgt gtccctgaat tccatctgac tctaatttta     6240

tgagaattgc agaactctga tggcaataaa tatatgtatt atgaaaaaat aaagttgtaa     6300

tttctgatga ctctaagtcc ctttctttgg ttaataataa aatgcctttg tatatattga     6360

tgttgaagag ttcaattatt tgatgtcgcc aacaaaattc tcagagggca aaaatctgga     6420

agacttttgg aagcacactc tgatcaactc ttctctgccg acagtcattt tgctgaattt     6480

cagccaaaaa tattatgcat tttgatgctt tattcaaggc tatacctcaa actttttctt     6540

ctcagaatcc aggatttcac aggatacttg tatatatgga aaacaagcaa gtttatattt     6600

ttggacaggg aaatgtgtgt aagaaagtat attaacaaat caatgcctcc gtcaagcaaa     6660

caatcatatg tatacttttt ttctacgtta tctcatctcc ttgttttcag tgtgcttcaa     6720

taatgcaggt taatattaaa gatggaaatt aagcaattat ttatgaattt gtgcaatgtt     6780

agattttctt atcaatcaag ttcttgaatt tgattctaag ttgcatatta taacagtctc     6840

gaaaattatt ttacttgccc aacaaatatt acttttttcc tttcaagata attttataaa     6900

tcatttgacc tacctaattg ctaaatgaat aacatatggt ggactgttat taagagtatt     6960

tgttttaagt cattcaggaa aatctaaact tttttttcca ctaaggtatt tactttaagg     7020

tagcttgaaa tagcaataca atttaaaaat taaaaactga attttgtatc tattttaagt     7080

aatatatgta agacttgaaa ataaatgttt tatttcttat ataaagtgtt aaattaattg     7140

ataccagatt tcactggaac agtttcaact gataatttat gacaaaagaa catacctgta     7200

atattgaaat taaaaagtga aatttgtcat aaagaatttc ttttattttt gaaatcgagt     7260

ttgtaaatgt ccttttaaga agggagatat gaatccaata aataaactca agtcttggct     7320

acctgga                                                               7327


<210>  979
<211>  6264
<212>  DNA
<213>  homo sapiens

<400>  979
cccgcaccca cctcccggcc ccaggcacac tgcatcggcg cggacgctcc ggccccggcg       60

aggtggctgc aaactcgcgg gcacgcacgg cgcccgggga gccgagggac tcgggggagg      120

ggacgcgcgc ggaaggcgcc agcttcctcc cgcccgcccc tggcagccgc gagccgaggt      180

tggaggcgcc cggggcccca gccgggcaga gccgagcggc ggcggcggcg gcggcttccc      240

ttttctcccc gagccgagcc ccggagcggc gcggggaccg gccctaaaaa gagcaggaaa      300

tcttgtttac cgcccgcgga gagaagccga tcgagccttt gtctggaaag tcagcatctc      360

cggctccggc tgcaatgtgt tcctggtgac attagcatcg ggcagacccg ccggaggagg      420

ggggtcgcca ggttcccgtc tgctttcgga ggcggatcga gcgggtgact tttgtgcatt      480

cgttttaatt tttggaaatc tctctttttt cctccctcgc tcgctgccgg gcatgtcctg      540

atctggcggc cgctcctacc accctgggca gccgagcaga gtcgtcccca gcgggtctcc      600

ctccctgcct ccctgacttt gcaacaccgc gttccgggag gaccggcctc ggcgagggag      660

gaggcggggg agctgcgaac acccagaccc aaaccctgac atgctctggg gcggagagga      720

ggaagccagg agctgagcgc gccgcggggg ctgcttcgcc ctccggctcc gagcgccggg      780

ctccgggcgc cctgccctgc gcctgggcag cagccttgct ggtcttgggg gcgccccccg      840

cttcccgccc cgggggtccg cggccggcag gaccatgctg ctgaaagagt accggatctg      900

catgccgctc accgtagacg agtacaaaat tggacagctg tacatgatca gcaaacacag      960

ccatgaacag agtgaccggg gagaaggggt ggaggtcgtc cagaatgagc cctttgagga     1020

ccctcaccat ggcaatgggc agttcaccga gaagcgggtg tatctcaaca gcaaactgcc     1080

tagttgggct agagctgttg tccccaaaat attttatgtg acagagaagg cttggaacta     1140

ttatccctac acaattacag aatacacatg ttcctttctg ccgaaattct ccattcatat     1200

agaaaccaag tatgaggaca acaaaggaag caatgacacc attttcgaca atgaagccaa     1260

agacgtggag agagaagttt gctttattga tattgcctgc gatgaaattc cagagcgcta     1320

ctacaaagaa tctgaggatc ctaagcactt caagtcagag aagacaggac ggggacagtt     1380

gagggaaggc tggagagata gtcatcagcc tatcatgtgc tcctacaagc tggtgactgt     1440

gaagtttgag gtctgggggc ttcagaccag agtggaacaa tttgtacaca aggtggtccg     1500

agacattctg ctgattggac atagacaggc ttttgcatgg gttgatgagt ggtatgacat     1560

gacaatggat gaagtccgag aatttgaacg agccactcag gaagccacca acaagaaaat     1620

cggcattttc ccacctgcaa tttctatctc cagcatcccc ctgctgcctt cttccgtccg     1680

cagtgcgcct tctagtgctc catccacccc tctctccaca gacgcacccg aatttctgtc     1740

cgttcccaaa gatcggcccc ggaaaaagtc tgccccagaa actctcacac ttccagaccc     1800

tgagaaaaaa gccaccctga atttacccgg catgcactct tcagataagc catgtcggcc     1860

caaatctgag taactttata taaatatctc atggggtttt atattttcat ttgttgttgt     1920

tgtttttttt taagaatctt ctgatagaga aaaagactgc tttgtcactc aaacatgttc     1980

cttcgacctt tcagtgtgca tgtgactcag taacttcaca tagaatatga ttccctaagt     2040

atgctacaca gcatcatatt agatgtaaga tgtaagactt gcaaaggaca gaaggaatct     2100

tctgtaacca catagctgta tgccagagag gaagccttgt tattgggcat ttgatgaggt     2160

ttggcatgga cttcaaggat aaatgaatga aaactttgca ccacttttgt tacaaggtac     2220

ggtagaaaat agtgaagtca gtttcctctc atcaaatcta aaattctcca aaatactctc     2280

aggcataaca tacttagctg ttaaattttg aactgctaat tactaatact tgaataccaa     2340

tagttactga gattcctatt ttgtggttag tctgactcag gatttggagc ctaattaact     2400

ctaaactttt gaaaatttta atcatcaagc tatagaggct ccaagtgcaa ttaataataa     2460

ctcatttata ccttccacag aatttaataa agattctact tgtttctgtc ttttaataac     2520

tttccccttt tgtgcccttg tggcctcaga aatccttaag aattgcatgg atgaatgtga     2580

ccataactga ttttggaatg gttcagttta ggaaccaaga ggcccaggtg aggcaacatc     2640

ttttttctct acaggtacca acaaaccttg acttgtcagc ttccatcatc aattaagatt     2700

ctcagaattt gcaattaatt gaatagaatt catttactat ctgcccactc aaagaagtac     2760

aagggtagag taagctaact gggctttaac atggtcagaa tgtctggtgc atgaactata     2820

aaaaagagaa ctgtctccca tccccttcct tgttttactc ttagtaacat ccagaattcc     2880

ctggaacaga ttgcctacca ccagacctta gaaaagactg tcattctctt gctccttact     2940

tgaaatacaa atattgggaa tgtcacagac atcaagcaac tactgtcaag tgggaggaga     3000

gaatgagcag aattgctgac tcctatttgt agagtgaaaa ggaggagtga taatagatgc     3060

ccttctgtct agctttcctt tcttcaacta gtggtaatgc aagattagaa tcaaggttga     3120

caggaggcaa ggtcactcac tgaagtgaca gaaagacaat tctcctttgc tccaaagaga     3180

gaaatctgtc acctttgcac ctcactgcct ttaaacacag acgggagggc aggccaaatc     3240

tcagcattga cttttgtcct ccaagagagg aagagaagaa gtaattgggc aacttggagg     3300

cccacgcccc agctagcctt cctgatcgta acctccaacc tcaggaaagg gaccttccca     3360

aaacacagat cccaaaggaa acaaaataga ccaaggagca taatctgctt ctctcacaca     3420

gcctctctgc cagtggaccc tgcctgcttc cctctcagtg ctcagcactc tgtgtagtgt     3480

ctttcaggtt gatacactct cccaaggtgc aggcgctggc cccatgagcc cagcaccaaa     3540

gttttctaag tcataggtca gactgtcaag atcatttctt tatctatagg ttgatattta     3600

gcttaaaaaa aaagaataaa cctagaactc aaaggaaacc tgttgcaaat agcttagatc     3660

aacagtgtat ctcttcccta agaatgatag tatcttagta agacaccttc tatgcatggt     3720

atggaagcat gatttttgct tgtgggaaaa cctaatattt tatcagaccc ctcggacttc     3780

tcaatccctc cctctccaca cagtagtact taatgaaaat gttttgcttt agagagcaaa     3840

atgctacttt cagaagacac tgaaatagta tatgtatttg cttaccattt gcaagctaaa     3900

atcaaggtgg gatggggtca ttattttcac atagaatgta tttattttgt gcaggctgtt     3960

aaacacatct ggcacctagt ttttccatta agagcattgc tattttccct ttttataaag     4020

tagcttctgc tgtcaaggtt aacaattcta tatgctttag gaagctaagt tctaatttcc     4080

ttttgtgagt ttcatttctt ttataaccag tatgttacca cagacatcag ttgcaaagct     4140

acgatgatag tgtgattctt agccgaaaaa aaagcgtgtg ctcttaaagt atgttcagtt     4200

tttctgtcta catatgcttt gtgtgagtta aaaagggggt gggtggtgta aatattcctt     4260

tagctgcttt gcatatttaa cccagtcatc aaaaggcata aatgacttca atattttata     4320

tatcttggtt ttcaagtatc atttcacatt ctctatacat gactttgtta ttgtggaata     4380

caagcctgca atggatgtat atatacagaa cattaataat tcttagaagg atggaagcca     4440

aatggctgca tgatggaaat tagaagaaaa aaaaagcaga aacttgaatt tgctaagcat     4500

gtttgggggg aaatagaatc cttaactcag tgcctctgtc tgcgatatgg aaaccttcaa     4560

ctttgttcac caaaattgta ttatacctgt gtatatatat atatatatat atatataaat     4620

ataaatatag tatagtgaat cagacaccat cagttttaag tctctggtag ccaaacttaa     4680

ataaataatc catagaatat cacatacgtt cactccatct tcatctctga agttagtgga     4740

gaccatcaaa atgactgtac atttcataac tctgggaaga tttcaaatgt gaagtgcccc     4800

tgtgcatttt cttggccata gcacggcatt cttgctttag ctgtgctttc ctgggatgag     4860

aagatcttgg tgtatttaac acataagctt tgttagaaat cacctctgaa gatcatttca     4920

ttttctcact ttgggttgtt gcaagacaaa gcaaaggaaa aggaacacaa tgaaggaggc     4980

cgtgacattt ttagttgcca ccgttgtaac tcaaacaata tgggtttgtt ggtgaactga     5040

tttatcaagg cttctgttac ggttttgcat ctgtgtgtga ggaaaatttt aatttatttg     5100

gaagtattta ttagccatgt tgttggtcct gaaaataaat ctctaagtag cacagttgtg     5160

ggtatattat gcagacactt accacaatac ctgcaaaagt aactgtggtt ttctttcaag     5220

acactgtaat aaacagtgaa ctaagagaat agattctgat acatctcgat aaatcattct     5280

ctgcaaaagt ttcagggcta atgtatttat gtgtattttt aaattctact ttctttggca     5340

tctcttcatg gctcagcgac aacaaagtaa taggtcattg gctggcttac gtcgatagga     5400

attttactct taagaagggc cagtgtatag ctgactctac atataatgtg taatcagata     5460

atccaataga gaggaattgt ccaaatagtt ttagtacctt tctgatcatc tgactcagta     5520

ggctaggaga caatctgtca tctgagccat agttcttgag atttaaaaag tctgtccagt     5580

gactgcaatc tgattatgaa taaactattt taactattca ttcttgctga aactgaagtg     5640

tacacaatag cacactgttg gcatgctgag gcaaaacatt gggttctttt gtgttctacc     5700

ttcaaaacaa tctgtttgca tttgaaatat aagtgtttaa gctttttagg agttagtgta     5760

ataagagaat gtgaatatgt tgggaaattt tcagatgcca ttaataattg taattttgtt     5820

gttaaattaa caaggacttt aggataagcc tcttgatgtt ttttgcttta aattgaaagc     5880

atgtctgtca aattgcaagt ctcccttcag tttctatata tcacccagga gagggtctct     5940

gagttggtgt tgtacctgta ccactcacat gtagctcaag tgtaatttgt agtgtttaca     6000

ttcaagctgg gatcttgatt ggttaaatta atccacatac cactgccact gctgaaggac     6060

caggtgttgg aatacacagc attacagact ataagcaaag caaacaaaag ttgatcctta     6120

catatgccat ccttctgtgt cattttgtgg ctgttctgtg tttttcttcc tagttattta     6180

ttattgttaa taacttactt tttcttacat tctgttgtaa ataaaataca aagcaatctt     6240

ctttgcaaaa aaaaaaaaaa aaaa                                            6264


<210>  980
<211>  2168
<212>  DNA
<213>  homo sapiens

<400>  980
tctggcgagg aagtaggccg ggctcaggcg ccttagccag agggcgggcc tgcgccaccc       60

tcggaaagcg tcacttccac ttccggccgg cgctctggct ctgtacctgg acagggctgc      120

ggtaggccag cggtgggctg gcggttgcgc tcctcagatc ggcggccttt cgggcggtgg      180

cttgcgtttg agcctcagaa agcgaggagc ggcctccacg gaagccaagc tggccgaggt      240

tgcagtccat gagctgggaa aggaggcagt gctcttggga gaaacagcag aggcctcaag      300

tttcgggctg aagccaacag agtcccaacc agtgggcgta tcccaagatg aagaattttg      360

gaatacatac gagggtctgc aagaacagct cagcaggaat actcataaag agactgagcc      420

tgtgtatgag agggctgtgc ctactcaaca gattctagct tttcctgagc aaacaaacac      480

caaagactgg acagtgacac ctgagcacgt cttgcctgag tcccagagct tgttgacatt      540

tgaagaagtg gccatgtatt tttcccagga agaatgggag ttattggatc ccactcagaa      600

ggccctctac aatgatgtaa tgcaggaaaa ctatgagact gtcatctctc tagcattgtt      660

tgtgctcccc aaacctaaag tgatctcctg tctagagcaa ggggaagagc catgggttca      720

agtatccccg gagtttaagg atagtgccgg aaaatctcct acagggttaa agctcaaaaa      780

cgacactgaa aatcatcagc ctgtgtctct ttctgactta gaaatacaag catcagcagg      840

cgtcatatca aaaaaggcca aagtaaaagt tccccagaaa acagcaggca aagaaaatca      900

ttttgatatg cacagagtgg gaaaatggca ccaagatttt ccagtgaaga aaagaaagaa      960

actttcaacc tggaaacaag agctgctcaa acttatggat cgtcacaaga aagattgtgc     1020

aagagagaag ccttttaaat gtcaggaatg tgggaaaacc ttcagagtta gctctgacct     1080

tattaagcac caaagaattc acactgaaga gaaaccctat aaatgtcaac agtgtgataa     1140

gaggtttaga tggagttcag atcttaataa gcacttaaca acacaccaag gaataaaacc     1200

atataaatgt tcatggtgtg ggaaaagctt cagtcaaaat acaaatttac atacacacca     1260

aagaactcat acaggagaaa agcccttcac atgtcatgaa tgtggaaaaa aattcagtca     1320

gaactcccac cttattaaac accggagaac ccacacaggt gagcagccat atacttgtag     1380

catatgcagg agaaacttca gcaggcggtc aagccttctt agacaccaga aactccacct     1440

gtgaagagaa gcttgtccag tgtcctcatt ctgaagacat tcaccaaatg gagcttggca     1500

ctaaaattta tgtaaaagaa aaatcacaaa ccttgaaaaa ttttacatca gaaaatggga     1560

taaacataca tttcacagaa aataatcaag acttgctctg cagccactca gtagtcttct     1620

gtggtcacag aagtaaacat tgttggcttt gtattgatct ctccagtcat ttttgaacac     1680

atccaataga aacattggca gcatggtctt ccaaaacaaa aagcagtaac atgcatgttt     1740

aattgcatac cattctcttc acagtagcag gcttaccaat ttccatagtc tcatgaggcc     1800

gaaatgaatt acaatgtaaa gtgttccagg aaccaaattg gattttcttt cttttgtcat     1860

tggacacggt ttgcaaagtt ggacatcact tgagttcctt cttaaacttt tcggcaactt     1920

ctcttggatc ctgttatcac agttttttac tgtgatgaaa tcttgttaac caccactagg     1980

gaatctccag atgaactatt aatgcactgt cttatgcctc tcattggtga tgtttggaaa     2040

atagaagaca tctctaatgg aatcatgggg gaaacgggtt ggaatttgta gccatggaat     2100

atatattaga tgtaaagaat tttctgcaat aaaagaaact agacttgtta aaaaaaaaaa     2160

aaaaaaaa                                                              2168


<210>  981
<211>  3985
<212>  DNA
<213>  homo sapiens

<400>  981
tttttttccc cgcctcccaa ccgtgaggtg ttgggtttgg gggacgctgg cagctgggtt       60

ctcccggttc ccttgggcag gtgcagggtc gggttcaaag cctccggaac gcgttttggc      120

ctgatttgag gaggggggcg gggagggacc tgcggcttgc ggccccgccc ccttctccgg      180

ctcgcagccg accggtaagc ccgcctcctc cctcggccgg ccctggggcc gtgtccgccg      240

ggcaactcca gccgaggcct gggcttctgc ctgcaggtgt ctgcggcgag gcccctaggg      300

tacagcccga tttggcccca tggtgggttt cggggccaac cggcgggctg gccgcctgcc      360

ctctctcgtg ctggtggtgc tgctggtggt gatcgtcgtc ctcgccttca actactggag      420

catctcctcc cgccacgtcc tgcttcagga ggaggtggcc gagctgcagg gccaggtcca      480

gcgcaccgaa gtggcccgcg ggcggctgga aaagcgcaat tcggacctct tgctgttggt      540

ggacacgcac aagaaacaga tcgaccagaa ggaggccgac tacggccgcc tcagcagccg      600

gctgcaggcc agagagggcc tcgggaagag atgcgaggat gacaaggtta aactacagaa      660

caacatatcg tatcagatgg cagacataca tcatttaaag gagcaacttg ctgagcttcg      720

tcaggaattt cttcgacaag aagaccagct tcaggactat aggaagaaca atacttacct      780

tgtgaagagg ttagaatatg aaagttttca gtgtggacag cagatgaagg aattgagagc      840

acagcatgaa gaaaatatta aaaagttagc agaccagttt ttagaggaac aaaagcaaga      900

gacccaaaag attcaatcaa atgatggaaa ggaattggat ataaacaatc aagtagtacc      960

taaaaatatt ccaaaagtag ctgagaatgt tgcagataag aatgaagaac cctcaagcaa     1020

tcatattcca catgggaaag aacaaatcaa aagaggtggt gatgcaggga tgcctggaat     1080

agaagagaat gacctagcaa aagttgatga tcttccccct gctttaagga agcctcctat     1140

ttcagtttct caacatgaaa gtcatcaagc aatctcccat cttccaactg gacaacctct     1200

ctccccaaat atgcctccag attcacacat aaaccacaat ggaaaccccg gtacttcaaa     1260

acagaatcct tccagtcctc ttcagcgttt aattccaggc tcaaacttgg acagtgaacc     1320

cagaattcaa acagatatac taaagcaggc taccaaggac agagtcagtg atttccataa     1380

attgaagcaa agccgattct ttgatgaaaa tgaatcccct gttgatccgc agcatggctc     1440

taaactggcg gattataatg gggatgatgg taacgtaggt gagtatgagg cagacaagca     1500

ggctgagctg gcttacaatg aggaagaaga tggtgatggt ggagaggaag acgtccaaga     1560

tgatgaagaa cgagagcttc aaatggatcc tgcagactat ggaaagcaac atttcaatga     1620

tgtcctttaa gtcctaaagg aatgcttcag aaaacctaaa gtgctgtaaa atgaaatcat     1680

tctactttgt cctttctgac ttttgttgta aagacgaatt gtatcagttg taaagataca     1740

ttgagataga attaaggaaa aactttaatg aaggaatgta cccatgtaca tatgtgaact     1800

ttttcatatt gtattatcaa ggtatagact tttttggtta tgatacagtt aagccaaaaa     1860

cagctaatct ttgcatctaa agcaaactaa tgtatatttc acattttatt gagccgactt     1920

atttccacaa atagataaac aggacaaaat agttgtacag gttatatgtg gcatagcata     1980

accacagtaa gaacagaaca gatattcagc agaaaacttt ttatactcta attctttttt     2040

tttttttttt tgagacagag ttttagtctt gtttcccagg ctggagtgca atggcacaat     2100

cttggctcac tgcaacctcc gcctcctggg ttcaggcaat tttcctgcct cagcctccca     2160

agtagctggg attacaggca cccaccacca tgcccagcta atttttgtat ttttaataga     2220

gagctaataa ttgtatattt aataaagacg ggtttcacca tgttggccag gctggtcttg     2280

aactcctgac ctcaggtgat cctcctgcat tggcctccca aagtgctgga attccaggca     2340

tgagccactg cgcccagtct acacactaat tcttgttagc ccaacagctg ttctgttcta     2400

tctacccctc atttcacgct caaggagtca tacctagaat agttacacac aagagggaaa     2460

ctggaagcca aacactgtac agtattgtgt agaaagtcac ctccctactc cttttatttt     2520

acatgagtgc tgatgtgttt tggcagatga gctttcagct gaggcctgat ggaaattgag     2580

ataacctgca aagacataac agtatttatg agttatatct tagttcttga aattgtggaa     2640

tgcatgattg acaatatatt tttaattttt attttttcaa gtaataccag tactgtttaa     2700

ctatagccag aactggctaa aatttttata ttttcagagt tgaagttggt gaagacattc     2760

atgatttaaa caccagatcc tgaaaggggt taaatctact ttgaaatgaa tctgcaatca     2820

gtatttcaaa gcttttctgg taattttagt gatcttattt gattagactt tttcagaagt     2880

actaaataag gaattttaac aggtttttat taatgcacag ataaatagaa gtacagtgag     2940

gtctatagcc attttattaa aatagcttaa aagtttgtaa aaaaatgaat ctttgtaatt     3000

acttaatatg ttagttaaga acccgtcaag cttatatttg ctagacttac aaattatttt     3060

aaatgcattt atcttttttg acactattca gtggaatgtg taagctagct aattcttgtt     3120

ttctgattta aagcactttt aaatcttatc ctgcccccta aaaacaaaag gttttgatca     3180

caaggggaaa tttaagattg ttaaccctgt ttttcagaag ggctactgtt aattgcacat     3240

aaacatgaaa tgtgttttcc cctgtgtact aacacattct aggcaaaatt caaacttata     3300

gtggtaaaga aacaggttgt tcacttgctg aggtgcaaaa attcttaaga cttctgtttg     3360

aaattgctca atgactagga aaagatgtag tagtttacta aaattgtttt tctaccatat     3420

caaattaaac aattcatgcc tttatagggt caggcctaca atgaataggt atggtggttt     3480

cacagaattt taaaatagag ttaaagggaa gtgatgtaca tttcgggggc attagggtag     3540

ggagatgaat caaaaaatac ccctagtaat gctttatatt ttaatactgc aaaagcttta     3600

caaatggaaa ccatgcaatt acctgcctta gttcttttgt cataaaaaca atcacttggt     3660

tggttgtatt gtagctatta cttatacagc aacatttctt caattagcag tctagacatt     3720

ttataaacag aaatcttgga ccaattgata atatttctga ctgtattaat attttagtgc     3780

tataaaatac tatgtgaatc tcttaaaaat ctgacatttt acagtctgta ttagacatac     3840

tgtttttata atgttttact tctgccttaa gatttaggtt ttttaaatgt atttttgccc     3900

tgaattaagt gttaatttga tggaaactct gcttttaaaa tcatcattta ctgggttcta     3960

ataaattaaa aattaaactt gtttc                                           3985


<210>  982
<211>  4305
<212>  DNA
<213>  homo sapiens

<400>  982
agatgccgcc tggcaccaag cgcagccgcc gctgccgcac tttccacttg tattgatcac       60

ctctcagccc cgcgcagccg gctcgcccga gcggaccgcg gccagcgcgc cagcccttgg      120

cagccccgga gcagtcgggc tccgggagga aactccttgg gagcgccctg tccggggtgc      180

cctctgcgct ctgcagtgtc tttctttctg cctgggagga ggaggaggag gaggaagagg      240

aggaggagga ggaggaggag gaggaagagg aggaggagga ggaggacgtc tggtcccggc      300

tgggaggtgg agcagcggca gcagcagcag ccgccgccgc cgccgccgct gccgccgccg      360

ccggaaaggg agaggcagga gagcccgaga cttggaaacc ccaaagtgtc cgcgaccctg      420

cacggcaggc tcccttccag cttcatgggc aaagtgtgga aacagcagat gtaccctcag      480

tacgccacct actattaccc ccagtatctg caagccaagc agtctctggt cccagcccac      540

cccatggccc ctcccagtcc cagcaccacc agcagtaata acaacagtag cagcagtagc      600

aactcaggat gggatcagct cagcaaaacg aacctctata tccgaggact gcctccccac      660

accaccgacc aggacctggt gaagctctgt caaccatatg ggaaaatagt ctccacaaag      720

gcaattttgg ataagacaac gaacaaatgc aaaggttatg gttttgtcga ctttgacagc      780

cctgcagcag ctcaaaaagc tgtgtctgcc ctgaaggcca gtggggttca agctcaaatg      840

gcaaagcaac aggaacaaga tcctaccaac ctctacattt ctaatttgcc actctccatg      900

gatgagcaag aactagaaaa tatgctcaaa ccatttggac aagttatttc tacaaggata      960

ctacgtgatt ccagtggtac aagtcgtggt gttggctttg ctaggatgga atcaacagaa     1020

aaatgtgaag ctgttattgg tcattttaat ggaaaattta ttaagacacc accaggagtt     1080

tctgccccca cagaaccttt attgtgtaag tttgctgatg gaggacagaa aaagagacag     1140

aacccaaaca aatacatccc taatggaaga ccatggcata gagaaggaga ggtgagactt     1200

gctggaatga cacttactta cgacccaact acagctgcta tacagaacgg attttatcct     1260

tcaccataca gtattgctac aaaccgaatg atcactcaaa cttctattac accctatatt     1320

gcatctcctg tatctgccta ccaggtgcaa agtccttcgt ggatgcaacc tcaaccatat     1380

attctacagc accctggtgc cgtgttaact ccctcaatgg agcacaccat gtcactacag     1440

cccgcatcaa tgatcagccc tctggcccag cagatgagtc atctgtcact aggcagcacc     1500

ggaacataca tgcctgcaac gtcagctatg caaggagcct acttgccaca gtatgcacat     1560

atgcagacga cagcggttcc tgttgaggag gcaagtggtc aacagcaggt ggctgtcgag     1620

acgtctaatg accattctcc atataccttt caacctaata agtaactgtg agatgtacag     1680

aaaggtgttc ttacatgaag aagggtgtga aggctgaaca atcatggatt tttctgatca     1740

attgtgcttt aggaaattat tgacagtttt gcacaggttc ttgaaaacgt tatttataat     1800

gaaatcaact aaaactattt ttgctataag ttctataagg tgcataaaac ccttaaattc     1860

atctagtagc tgttcccccg aacaggttta ttttagtaaa aaaaaaaaaa caaaaaacaa     1920

aaacaaaaga tttttatcaa atgttatgat gcaaaaaaag aaaaagaaaa aaaaaaagaa     1980

aagaaaactt caattttctg ggtatgcaca aagaccatga agacttatcc aagtgcatga     2040

ccggattttt gtggttttgt tcattttgtg tttaatttgt gttttttttt tccagctgta     2100

tgaaatgggc tttctgaagt ttaaatagtc cgacttcacc catggtgttc tgtgcttgca     2160

gtgcgagtgt tgctgtaatt cagtgttgcc gtcagtgtct cttttcttag ctttctgtct     2220

ttctttcaac gtagtgtgaa gtgtcttatc cttttctatg aattccaatt tgccttaact     2280

cttttgatgc tgtagctgtt tcagtaaaag ttagttcaaa ctaatgatgt agaatgcttt     2340

gaccaaatga gctggtctat tatgccttgt aaaacagcag catagggctt ttaaaaggta     2400

gtcaataaaa gttgctgaaa ttttggcttt tttaaatatg tagtaggtgt ttttaatgat     2460

ttttcacata atgtgtaagg tagtgaaatg caagaaggga aaaatgtttt gtgtgaaaca     2520

cattttctga ctggggaact tttattaggg taaattgttt gtaaggctgt acgccaacag     2580

tttcctctga tagtttgact gatttaggat atctgctgta tgatgcaatg taaagtcttt     2640

tttgcctttt ttcaggaaaa aaaaaaagct aacttgatgt actagattta gtgtaggtag     2700

tgttggggtt ggggatgggg gtgggggagg ggagtcactg aatgttttgt ccttccttta     2760

tactaatgat agtgctttag aatgagaatt atgcctgaaa tctggcaaac cgaaaaatgt     2820

tgctattgca acaaagtggc aaaagctaaa agtaaggatt tatcttcaaa cataagctga     2880

gataacgaat agaagcaaaa cgattggcta ctagctctct ctctctctct ctattaggta     2940

aatttgaaaa ataaaaatga cttggcactt ttaaaggtaa cttcaccaaa gaccgaagag     3000

ccagtaacca gtagctccaa cttgtctcag catcacatct tctgtgctct ttatttttgc     3060

cggaccagtt tgcggttagg agaatgtgcc ttttttgtac ctttgcattt aggttttata     3120

attttaattg atgtatggac acacacaaac aaaaaagcat gaaggaagat ttggatccaa     3180

gcagtgccac actttacatc atcactacaa gtgttcaagt gtaaagaaaa ccaattttga     3240

aactatgaaa ttcctgattc ataaatacac agttatttct actttagtac atataagata     3300

attcactgtt attaaagctc ttttattaag gcaattgcat atgttttaaa agcaatggta     3360

aattaagttg tcttccaaaa ctgtgtactt gtctggtcag ctgtgtatga tcagttatct     3420

acctcagagt ctattttctt ttgtgctggg acaggttgct ggccctccct gtttccacag     3480

accaaatcct cctagctcag gagctagggc taagcagtta tttctttcaa gtatttttta     3540

gttcttaaat tttatgcttg tatttgatga tagatgtcag tgacatttca tagtttcaaa     3600

agtccttgct gctctgagaa gtgtagattc tagtgaaaat tacatagtca taagagaaat     3660

gtgtttttgt ttttgttttt gtttcatttt tttaaagttg tggtattatt ggttctatgc     3720

tccctggaat attactgctt tgtgaaagtc cagactgaac gcagcaccct ctgtgtacct     3780

agtacagtta taaacctggg tctctcacta cttgatattt ttgcattagt taagacagaa     3840

atttgatagc tcggttagag gggaggggaa atctgctgct agaaatgtct gaactaagtg     3900

ccatactcgt ctgggtaaga tttgggaaac ataacctctg tacataaaaa aaaaaaaatc     3960

agttaaacat cacatagtag acagccatta aattataaaa aaattaattt atgaagaaag     4020

accttttgta cagattgaaa aaaaaagatt ttcatagaga tatctatatg atcaagagag     4080

ttaatttttt atttttgttt tactagtgcc acagacttgc cagtggtaac ttatttgtcc     4140

ggttcaagat aactctgtag ttttctttcc taggacttgt tgttaaacgc caaaagacat     4200

ttttgaactg tacatttgat cagattgtta gcttttctgt tttatttctt ttgagaacct     4260

ttgaataaaa aacatctgaa attttaaaaa aaaaaaaaaa aaaaa                     4305


<210>  983
<211>  5288
<212>  DNA
<213>  homo sapiens

<400>  983
aaccaaacaa cccccaacag ccaagcatac atctctaatt ttattatttt ggtcttttcg       60

ttggattttc cctttcttct ttttttcggg ttatcgctca gttttgagca gaggtttaca      120

ttttttaaaa atttgctttc cagcccgcct tgatcttcta agtgcgagtt catcgtctga      180

gaaaaaaaaa aatctctggt tggcgttttt gtttcttttc ttttctttct tttctttcct      240

tttttttttt ttttaatttt tttcaagggg gaggagattt tccacaagaa aaggttgttt      300

tcatgtttgg gattcaggaa agcatccaac ggagtggaag cagcatgaag gaagagccgc      360

tgggcagcgg catgaacgcg gtgcggacgt ggatgcaggg cgccggggtg ctggacgcca      420

acacggcggc gcagagcggg gtgggtctgg cccgggctca ctttgagaag cagccgcctt      480

ccaatctgcg gaaatccaac ttcttccact tcgtcctggc cctctacgac agacagggcc      540

agcccgtgga gatcgagagg acagcgtttg tggggttcgt ggagaaggaa aaagaagcca      600

acagcgaaaa gaccaataac ggaattcact accggcttca gcttctctac agcaatggga      660

taaggacgga gcaggatttc tacgtgcgcc tcattgactc catgacaaaa caagccatag      720

tgtatgaagg ccaagacaag aacccagaaa tgtgccgagt cttgctcaca catgagatca      780

tgtgcagccg ctgttgtgac aagaaaagct gtggcaaccg aaatgagact ccctcagatc      840

cagtgataat tgacaggttc ttcttgaaat ttttcctcaa atgtaaccaa aattgcctaa      900

agaatgcggg aaacccacgt gacatgcgga gattccaggt cgtggtgtct acgacagtca      960

atgtggatgg ccatgtcctg gcagtctctg ataacatgtt tgtccataat aattccaagc     1020

atgggcggag ggctcggagg cttgacccct cggaaggtac gccctcttat ctggaacatg     1080

ctactccctg tatcaaagcc atcagcccga gtgaaggatg gacgacggga ggtgcgactg     1140

tgatcatcat aggggacaat ttctttgatg ggttacaggt catattcggt accatgctgg     1200

tctggagtga gttgatcact cctcatgcca tccgtgtgca gacccctcct cggcacatcc     1260

ctggtgttgt ggaagtcaca ctgtcctaca aatctaagca gttctgcaaa ggaacaccag     1320

gcagattcat ttatacagcg ctcaacgaac ccaccatcga ttatggtttc cagaggttac     1380

agaaggtcat tcctcggcac cctggtgacc ctgagcgttt gccaaaggaa gtaatactca     1440

aaagggctgc ggatctggta gaagcactgt atgggatgcc acacaacaac caggaaatca     1500

ttctgaagag agcggccgac attgccgagg ccctgtacag tgttccccgc aaccacaacc     1560

aactcccggc ccttgctaac acctcggtcc acgcagggat gatgggcgtg aattcgttca     1620

gtggacaact ggccgtgaat gtctccgagg catcacaagc caccaatcag ggtttcaccc     1680

gcaactcaag cagcgtatca ccacacgggt acgtgccgag caccactccc cagcagacca     1740

actataactc cgtcaccacg agcatgaacg gatacggctc tgccgcaatg tccaatttgg     1800

gcggctcccc caccttcctc aacggctcag ctgccaactc cccctatgcc atagtgccat     1860

ccagccccac catggcctcc tccacaagcc tcccctccaa ctgcagcagc tcctcgggca     1920

tcttctcctt ctcaccagcc aacatggtct cagccgtgaa acagaagagt gctttcgcac     1980

cagtcgtcag accccagacc tccccacctc ccacctgcac cagcaccaac gggaacagcc     2040

tgcaagcgat atctggcatg attgttcctc ctatgtgaaa gaattgcctt gaagaattgt     2100

attaatgaag aggttggatt ctgctacaga gagtaatctg atacaagtcc cagagtggaa     2160

cttttaactc aggccttttt aagaggaatc acaataactg cagattttta aacaaacaaa     2220

atcaccgacc ttgcaaatac tgaaattgga agagggatct gcaagtgcag ggtgttggtt     2280

aaagttgtac ctcccaagta tttgggggat atatttattc tgtattgaca aaagcaaatc     2340

cactttttct ttttcttttt tttttttaag cttaattctg caatcatttg tcttttataa     2400

accgtaaagc tctatacaag ggacactata aataagactc catgttttaa tttatgatgt     2460

ttttaaagct gtgtaaagga agaatgaagt ggtgatattt acaaaaaagt aaaaaaaaaa     2520

aaaaagaaaa aaaggaaaaa aaaaaaagct tgtatgggac agaataggaa tgccagttag     2580

attttttaga aaaactaagg gtcggctttt gcgccttaaa gcatatcaaa tggtagttag     2640

ctcagacagt gcattttcaa tatctaactt aacatgccac cccttagcag tgcaagctta     2700

tttatctctt ttgtattgtt gtcttaagca actgtgtaaa taaatgcagc ctggaaagtt     2760

aaaacgcgat gtaagtgatc acatttttcc ctctactcga aaatccagtg cctctagaca     2820

gattgttaaa actgcatatt taaatctgat ctcattctct ccttttactt aagtcagttt     2880

cttctgaagc cgatggcctc tcgagagctt ggtggcacac atactgtgtg agaatctcct     2940

ttgagacttc atggaacagg gtccaggcac agaattccac actctgccct ccagttaaca     3000

agccaaaacc tcacgtacgc tcccccattt gcaagtttaa agtttactcg tcctaaatgc     3060

agacttcata cctatcttcc aaaagttgat aaaagcaacg tggcaggtat tttcgatttt     3120

cccattccag atactgcctc tatcagtcga cccttaccat ttgtaacata atagattgaa     3180

acaacaggtt aagtgctttg gaattaagag ttaaagggaa ccgggggtgg agaaaggaaa     3240

agaaggttga gacctccaaa acatagtttt ctgttctatg ggaatttttg ctctcattat     3300

ctgggaagtg ttcttaaaaa taagaattaa tagcaaagat gcagcaaagc tctgaggatg     3360

catttgcctg atattttttt ctttgctctt gtgtttttgt atgtagttat aaatactgta     3420

gatttttttt ttgtgatttt ttgccaaagt tgttgttcta tttatacatt ttaatgtctt     3480

aagacatttt ttcaatatca caaaaagatt ttactgcgta ttttgcaaag aaaaaaagct     3540

cactaccttt agcttgcaca tacttgcaaa gttaattaaa aggctttttg ttttaaaggg     3600

gattttgtaa aatatccata taaataatgt atttatcttt cgaatttgta cattgctttt     3660

cccttcttcc tcttccttcc acccccaatt tattttattg tgtatgtttg ctacgtgaaa     3720

agtgcgtatt tgtttggtca cctacacttg tattagctgt ttcaatgtga tttttaaaca     3780

tttcatttat agttattttt agtattgtta taaaccatgc ttcagttttt ttaatttcca     3840

cccaaaagtc attgtctatt tttgtattat ttgtaagtta agaagttttt tccaatatat     3900

ggcaaaaaaa aaaaaatagt agcatattat tcttgtagta tttagttcag tagatttaaa     3960

aaaaaatgta tcctttgctt tggaagctta caaaacaacc ctaatgctgt tttactctat     4020

taatatgcat ggaatctctc cctttggagt gacgcatttt gtgcattaaa ttctagggag     4080

aaacttcata gaaatcaatg aacatacttt ctttcttaag tctgcttgta tatttcctct     4140

gtctttcaca taaatataaa ccagcagatt ggatgcctta acaatgcaaa tcatattcat     4200

ttcacttgta cattgtaact gtgcaccaga actgtcagtc atcactaaca ttctaagaaa     4260

aaagaaaaag aaaaaaagaa aaaaaaaaaa acaaagaaat cgaaaagcac aaaagaactg     4320

ttttgttacc ttaagacaat gtaacttttt ctagtagagc aagaaatcat ttacaacaat     4380

gctgcaactg tgcatgcccc catatggatt ttgcaatggt tttcactagg ctgtcaagag     4440

tgcgattttt atgggttggg gtgggtgggg gaggggagtt gtgggagggt aggggaggga     4500

ggaaagctgt ttttcatggt gagaaataat aatgatgact aataataata aaaaaaactg     4560

gaaaatgtaa gcaaggtgga cgcattgctt ctcggtactc agaaaggtta tctgaatttg     4620

cgtggtaagc gctggcctga agatgtacac aagttaaagc catattttat ctggtgagcc     4680

ccttaactgt ttctgaagga atgaacggtc agccgggaag gtgtccggct tagaccttga     4740

caacagacac tacccatctg tcagccatgt gcagtggtta gaactcttct tgaaagtcca     4800

aagagccttt aaaatgtgta taatttgtgt tttgttgctt ctatttctat tgattagatg     4860

aaaagacatt ctggccctct gatcctcttt cttctccaca aaagttttac aaataaaaga     4920

tgttccccta aatacagaat atggctttaa gaagaaaatg aaatgaagaa ttaaattaag     4980

atttcagtgt tgggggaaaa aatacagctt ctggatgact ggattgcata acattgccct     5040

ggcctcacat tgtactagga tgcagcttaa atgaagtcat ctctaaatct actaaccttt     5100

caccttctta tcaaaacttt ttgaatagac acacactgta cagttcaatt gttagagaac     5160

ctaactactg tagagattgt taaatttttt tttttttttt gcaaaaattc aagctgtaaa     5220

aacttttcaa ctttcacaat atttaattaa agttacttcc tgtctgtgat ggcaaaaaaa     5280

aaaaaaaa                                                              5288


<210>  984
<211>  4412
<212>  DNA
<213>  homo sapiens

<400>  984
gcgccgctgc tcgaggaaac gctttcggcc gggagctgcg gccgccgcca gcagttttca       60

tgtttgggat tcaggagaat attccgcgcg gggggacgac catgaaggag gagccgctgg      120

gcagcggcat gaacccggtg cgctcgtgga tgcacacggc gggcgtggtg gacgccaaca      180

cggccgccca gagcggcgtg gggctggcgc gggcgcactt cgagaagcag ccgccttcca      240

acctccggaa atccaatttc ttccacttcg tgctggcgct ctacgatagg caggggcagc      300

cggtggagat tgaaaggacc gcttttgtgg actttgtgga gaaagagaaa gagccaaaca      360

acgagaaaac caacaacggc atccactata aactccagtt attgtacagc aacggagtca      420

gaacagagca agatctgtat gttcgcctca tagattcaat gaccaaacag gccatcgtct      480

acgagggcca ggacaagaac ccggagatgt gccgtgtgct gctgacccac gagatcatgt      540

gcagccggtg ctgtgacaag aaaagttgtg gcaatagaaa cgaaacgccc tcagaccctg      600

taatcattga cagattcttt ctaaagtttt tcctcaagtg caatcagaac tgtttgaaga      660

atgcaggcaa ccctcgagat atgcggagat tccaggttgt tgtatcgaca acagtcaacg      720

tggacggcca cgtgctggcc gtgtcagaca acatgtttgt gcacaacaat tccaaacacg      780

ggaggcgggc ccgccgccta gacccgtcag aagccactcc gtgcatcaag gccatcagtc      840

ccagtgaagg ctggaccacg gggggtgcca ccgtcatcat aattggcgac aacttctttg      900

acgggctgca agttgtattc ggaactatgt tggtgtggag cgagctgata actccccatg      960

ccatccgagt ccagaccccg ccgaggcaca ttcctggcgt cgtcgaagtg accctctcct     1020

acaaatccaa gcagttctgc aaaggtgctc ctgggcgctt tgtctacacc gcccttaatg     1080

aaccaaccat agattacggc tttcagaggt tgcagaaagt gatcccaaga catccgggtg     1140

atcccgaaag gttacccaag gaggtgttac tgaagcgggc ggcggacctg gtggaagcct     1200

tatacggaat gcctcacaac aaccaggaga tcatcttgaa gcgagcggcg gacatcgccg     1260

aggcgctgta cagcgttccc cgcaatcaca accagatccc caccctgggc aacaaccctg     1320

cacacacggg catgatgggc gtcaactcct tcagcagcca gctagccgtc aacgtgtcag     1380

agacgtcaca agccaacgac caagtcggct acagtcgcaa tacaagcagc gtgtccccgc     1440

gaggctacgt ccccagcagt actccccagc agtccaatta caacacagtc agcactagca     1500

tgaatggata tggaagtggc gccatggcca gtctaggggt ccctggctcg cctggatttc     1560

ttaatggctc ctccgctaac tctccctacg gcatgaaaca gaagagcgcc ttcgcgcccg     1620

tggtccggcc ccaagcctct cctcctcctt cctgcaccag cgccaacggg aatggactgc     1680

aagctatgtc tgggctggta gtcccgccaa tgtgagggac ttctgtttac cttccgcagc     1740

acccagcatc aaaggacgga cttcagggga cacgtttagt atattaagac atgctgatgg     1800

aaacagtatc ttcaaaaaaa tcagcagcaa ttgaaatgct acaaaagact ttgtttaaag     1860

attttattta aactattaag aatcaacatg caaacagcct acttcttcat gaacaattcc     1920

attttattga ctgaactttt ctcatatttt cacatttctc agtcctgaag aataaggaaa     1980

acaaagcgac gcctattttg tataaagttt ccgactccgt cttggccatg tctagtaatt     2040

gctatgtgtt gggagaaact ttgtgaatgc accattttga tgatcatgaa acgctgatga     2100

aaaatgcctc caaacatttt tctgtactca tacttagatt cacaatggtt gtgtatctct     2160

ataatgtgaa atattttttt gtggtgataa aaagagggcc aaggaggtat gagccatcag     2220

actggaaaaa aggatgacta tatgatgagg agaaactggg gtggcaggga gggagggagg     2280

gtttatcact gcttaacttc atcttcatga aatgaaactt tgtaacttat tgtagttaga     2340

aattgtaact ttgatattga attctcttgc cttcaacaag cacactgaca gagaaaaaat     2400

gctactgtct gttggttcca atattctccc actgctagag cttcctgtta agcaagtgtg     2460

atctgcaaca ttttttcaac ttttgctagc actgtatact attgcattct taggctactg     2520

tgaggtctat gtttcttgta ccagaaattg tccttttgac ttctagatcc ttcttcccta     2580

atgtgttttg tatgtggtta taaaattgta gacttttgtg attttgccaa agttgtagct     2640

aaatatttat acacttgtct tgaatttttt tcagatccac ttaaaatatt tagaaaaaca     2700

agttttattc cttatgtgtc ttataaggaa taaaatggtc ttcatttgac acttactttc     2760

ccatgaacac ttgcagttgc taagggactt tattttgtaa catatcaatt ataaatattg     2820

tatttatctt tgaaattttg tacattgctt ttcccacctt ttcctttttc ttctttcttg     2880

tctgtattgg tttttgatca cggcctggtg ttgtgatact gggaagagca ttagccaaga     2940

acttgtctct ttgatctgtt tcgttaagct gaaccagtgt ctttacattt catttgtact     3000

tcaaaaaata tgctattgtt tagactttcc atcctttttt tttttatttt gaggaaaagt     3060

caaattcatt gtttattttt atattatttt taagttatct gaacaaatac ttttgaaaaa     3120

aaagtttgtt gtatagtcaa aacaaatcgg tgccacccgg ccgtgacaaa tcctagtaga     3180

ttctgtgcat gtggagcggc cgcgaagagg tgacaccgtt tggggctgtg tccttatttt     3240

attttatttt tttgtagaat gtaaaaagtc attttagatg ccacccattg actttgccac     3300

atagctgaac tgtgtttact ggaaaaattc agaggcctaa agtttaaaat aaaatttact     3360

tctgatgttt taattaaaat gtttgccaca ttaacttttc tgatgcctta aaagtgaact     3420

tctttaaaga acctttgtgc tattttatca caggcttaca ctacaattgt taataaatac     3480

ttcatttgga gatgtatggt gtaaaacaca caaacacaca caaaaaagca caagcccgct     3540

gcatgacccg tctctccttt ctgggactat ttctgctgcg tcctgcaccc tcctgggccc     3600

acctccgatt cacagaggtt tcagggggac ccaaatcact gctggttttc aatttttttt     3660

taacaataca tttttgtggt cagttccaac agcactgtcc gtacttttaa aactggaatg     3720

acctccttca gatatcgtgc ctcttagtgc caaacccaca gtgagaccaa aagtgtcagg     3780

tgtttttttt tttttctttc tcctttgcac taagtgcttt gcagacacgg cacagcaaac     3840

attttgcaaa ctgcagcaga aatcgaattt aaaacaaaaa ggagggactt taaaatacct     3900

tcttgacaaa aatcaacaat gcacaactta caaagtgttc attctaggga caaaattaaa     3960

taaacagaat gtccccagga gtcagcaggt cacagtctgg ctttgtgatg gttgacaagg     4020

tctagctaca tgggaaagcc tgagaagtca ctttggaact aaattgcctc cattttattt     4080

tgtacgagta agggtttgat ctacaaaaga gctcacatgg acgcactgag aacgcctgcc     4140

agcttcccca tgccctcact tggtttgtgt tttaggttaa gtagtcaatg cccacatcac     4200

ttcactgtct caagactgag cacttcacta aatggtagat tttactgtta aagaccctac     4260

aataagattg ttttatctgt acattttttc agatatttaa ctgtataaaa atgttcattt     4320

tacacaatat ttaattaaag tatttcttgt ctgtgaattt cacttttggt aattttctct     4380

gtttttgatt attaaaatga ctaaacacta ac                                   4412


<210>  985
<211>  1947
<212>  DNA
<213>  homo sapiens

<400>  985
gcgagagttc ccaagcggta ggcggcggcg ccgggagaga agcgccgcct agctgcgctt       60

ccgcaaagat ggcggcggct gcgggtagct gcgcgcgggt ggcggcctgg ggcggaaaac      120

tgcgacgggg gctcgctgtc agccgacagg ctgtgcggag tcccggcccc ttggcagcgg      180

cagtggccgg cgcggccctg gcaggagcag gagcggcctg gcaccacagc cgcgtcagtg      240

ttgcggcgcg ggatggcagt tttacagtct ccgcacagaa aaatgttgaa catggaataa      300

tatatattgg gaaaccgtct cttcgtaagc agcgcttcat gcagttttct tcactcgaac      360

atgaaggaga atattatatg acaccacgag acttcctctt ctcagtgatg tttgagcaaa      420

tggaacgtaa aacttcagtc aagaagctga caaaaaagga catcgaggat acactgtcag      480

ggatccaaac agctggctgt ggatcaactt ttttcagaga ccttggcgat aaagggctaa      540

tttcatatac cgagtatctt ttcttgctta caatcctcac taaaccccat tctggatttc      600

atgttgcttt taaaatgctg gatacagatg gtaatgagat gattgaaaaa agggaatttt      660

ttaagctgca gaagatcata agtaaacaag atgacttgat gacagtgaaa actaatgaaa      720

ctggatatca ggaagcaata gtgaaagaac ctgaaattaa cacaactctt cagatgcgtt      780

tctttggaaa aagaggacaa agaaaacttc attataaaga atttcgaaga tttatggaaa      840

atttacaaac agagattcaa gaaatggaat tccttcagtt ttctaaaggt ttgagtttca      900

tgagaaaaga agactttgca gagtggctac tttttttcac taacactgaa aataaagata      960

tttattggaa aaatgtgaga gagaagttgt cagcaggaga gagcattagt ttggatgaat     1020

tcaagtcatt ttgccatttt acaacccact tggaagactt tgctattgcc atgcagatgt     1080

tcagtttagc tcatcgtcct gtcagactag cggagtttaa gagagctgtg aaagtagcaa     1140

caggacaaga actctcaaac aatattttgg acactgtctt taagatcttt gatttggatg     1200

gtgatgaatg tcttagtcat gaagagtttc ttggggtgtt aaaaaacaga atgcatcgag     1260

gtttatgggt accacaacat cagagtatac aagaatactg gaagtgtgtg aagaaagaaa     1320

gcattaaagg agtaaaagaa gtctggaaac aagctggaaa aggtcttttt taataaaaga     1380

tataatagta tggcaattat attgttccaa atgtcaaaat ttgtgatttt ttagaagtac     1440

ttgctattta tcttcttaag tcttcattga tattctgtgt gaaataagca tgtcttgtac     1500

ttgctttctg attcataatt ttattaaaga acttagtaga aagaaaagta agtataaaaa     1560

tagatattgg attctgtcag aaggcctaga tttgaaataa tgttttgtac ttcggtaaga     1620

tggaaaactt agtgattcac tgatttctta gacactctaa tatgatatgc tttctggaag     1680

gataaaacaa atacatatgg gaaaaagtac ttgagaccaa ggccagcatc aattccagac     1740

atcttcatgt tcctaatagg ctaaatgaag ttaaaaactt atttcagatt tttctcatct     1800

gtaccttata tctcataaat ttattgcata ttttatgtca gtagcttagc tgtttattgt     1860

ctttaaaata acatgtaaac ttcaatgttc tatctggaag cagaataaaa tatttacata     1920

gatacaaaaa ataaaaaaaa aaaaaaa                                         1947


<210>  986
<211>  3224
<212>  DNA
<213>  homo sapiens

<400>  986
aggccccacc cgctggtggc ccggtccgcg tgtgcgccga ctctcgcact ctcctcgctc       60

cgggcgccca gactctgaga gagagcgacg gccatcatag aacagcgaag gcagtcgatc      120

ggcctgcggt ccgcttcggc attcgcaggc cgcaggcggg aggctagagc ccccaggcgc      180

acctcgcccc aaccgcccgc ggctcgggca gctctgcaga gacgtcgtgg cggcagggcc      240

agcacccatt ggtccgccac agccctccgc cctccccctc gccacgctta ttggccggag      300

cggcggcgct cgccgggtag gcggtggcgg cgtccctccc ttgcgccggc cctcaagagg      360

cgacgaggaa gcggccgcct ccctgcgccc cgcccctccg gctagctcgc tggctcccgg      420

ctcctcccga cgtctcctac ctcctcacgg ctcttcccgg cgctctcctg gctcccttct      480

gccccagctc cgtctcggcg gcggcgggca gttgcagtgg tgcagaatgg ctgacctcag      540

tcttgcagat gcattaacag aaccatctcc agacattgag ggagagataa agcgggactt      600

cattgccaca ctagaggcag aggcctttga tgatgttgtg ggagaaactg ttggaaaaac      660

agactatatt cctctcctgg atgttgatga gaaaaccggg aactcagagt caaagaagaa      720

accgtgctca gaaactagcc agattgaaga tactccatct tctaaaccaa cactcctagc      780

caatggtggt catggagtag aagggagcga tactacagaa gcctagcgtg tctctcaaca      840

ctggggctgc tgcaacacca gaccagtgat ctttcctaag catcgttata cttctaaaac      900

cttcagcatt ttgcagagct ttgcttttca ttcctggaca tgatgtagaa gaaactgagg      960

gtagttcttc ggggcctatt tctgctgatg cctgagcaaa caacctgctt cctcttgtgc     1020

tctgcagggt ttgatggagc ctcatttccc tttgtgaaca caaagtgcaa aatgaattct     1080

ttttaatttt agtaattttt acaaaggtta tctaatgtct tttatttctt gttttcttta     1140

tgattttatc atttgattca ttctcacatt tttttccttt aaatattttt agttgacctt     1200

tttcctttgg ttttcaaatg ttcaacatga atcagaatag tgtaacacca aatgagaaca     1260

tgtgttttca taaaggggtt gaggccacca gtactgcagc gaatttcctt ttcttctccc     1320

tcctccttcc ttctctgagc ttgcttttag ggaaggttaa tcttacaggc tacctatgtt     1380

tctctccacc ttactaaaat ctaaataatg atagatattt taagttttta aattgagtag     1440

ttctgagtaa tcctagaata tttttccaaa ttaaataatc ctttattatt tgcaagttgg     1500

gccaaatttt tttttttttg gagacggact cttaacaatc taagattgtt tcaacaggac     1560

tttcttattc ccattcctaa ttttttcaaa ctaattgctt aaatctagaa ccagttgaga     1620

ttagtactgt acaatggtat gctttgattg tatttataga aatataacat aaaacatgga     1680

ccatgttttg aaatcttaga ggaattctgg tttaaaatct gaaatacttt aaagttttct     1740

atccttttac tgattatgca gcttcttata acccccaagg tacagattat ttcagcttaa     1800

aagaaataat tggcaccatg ttctgagaaa gattttgaga tatacattgt tttttgtttt     1860

tgagacaggg tctcactctt gcctaggctg gagtgcggtg gcgcgatctt ggcttactgc     1920

accctctgcc tcccaggttc aagtggttct cctgcctcag cctcccaagt agctgggatt     1980

ataggtgtgc gccaccacac cagctaattt ttgtattttt agtagagacg gggttttact     2040

ttgttggcca ggctggtctc gaactcctga tctcaagtga tccacccgcc ttggccaccc     2100

aaagtgctgg gattacaggt gtgagacact gtgcctggcc agatatacat tgttttagat     2160

cccctgatac agaactactt ttgagatggt aagattagaa tatcatgaaa gtttaaactg     2220

aatccttgca gcgacttccg gaatttagga agcattccct cttctacagg ggtctggtca     2280

caagggctgg attctctgac aaaaatttct tctatggatt ctggacagaa gacacttgag     2340

ggtgatatgt tttaaaggaa agaggttatg cttatcttct tagcagttga taaaatatta     2400

aaactctctt gccatagaga atacaccatc aaagaaaaca caaccctttc cctttggtgt     2460

acagttattt attaagttga ttttggggtt tctttcgcca gggatctttt caaaactggt     2520

agtagttatt tttaaaaatc atgtttgaca tctttctatt gctcgtaacc agtccctgta     2580

gctgtctaag ttatgggtgg agaagcctgg gtatgacttt ccgttgtgta cactcacact     2640

tcatgattga catttattta ttcttttatt tccatttggt tatgcttatt tttgtttgaa     2700

atttgttttt ttcaaatatg tttccttttt gaacttacag aattgttgaa attttctact     2760

aacagccagc taaaatttgg tatatgttag ctctatctgt ttcacttgga cgtttcattt     2820

tgaaagaaag aaattttatg tttcacatat agttttatac aaagtagcca gtcccataat     2880

gaaatgctgt attgccatag tggtcacacc caagtggtcc agtatctcaa tggtgaggca     2940

gccagactgg tcagggctgc tttgttgaaa tgtgatgatt ttcatatgcc ttctttctct     3000

ttctctctct cttttttttt ccttttttgg cccaatgttg aagatgtaga actttgtttt     3060

taaataatgt ttttataatt tcattcgtat acctaagttt gtattttttg tgactttgga     3120

cttcaacagt ttgtatattg ggacttctaa tgtgattact gtactaaata aattccacta     3180

ataaacatct tacattaaca ccttaaaaaa aaaaaaaaaa aaaa                      3224


<210>  987
<211>  2816
<212>  DNA
<213>  homo sapiens

<400>  987
agagggatgc gggcggcaga gctcgagagg cggctgccgg gctgcggggc gccttgactc       60

tccctccacc ctgcctcctc gggctccact cgtctgcccc tggactcccg tctcctcctg      120

tcctccggct tcccagagct ccctccttat ggcagcagct tcccgcgtct ccggcgcagc      180

ttctcagcgg acgaccctct cgctccgggg ctgagcccag tccctggatg ttgctgaaac      240

tctcgagatc atgcgcgggt ttggctgctg cttccccgcc gggtgccact gccaccgccg      300

ccgcctctgc tgccgccgtc cgcgggatgc tcagtagccc gctgcccggc ccccgcgatc      360

ctgtgttcct cggaagccgt ttgctgctgc agagttgcac gaactagtca tggtgctgtg      420

ggagtccccg cggcagtgca gcagctggac actttgcgag ggcttttgct ggctgctgct      480

gctgcccgtc atgctactca tcgtagcccg cccggtgaag ctcgctgctt tccctacctc      540

cttaagtgac tgccaaacgc ccaccggctg gaattgctct ggttatgatg acagagaaaa      600

tgatctcttc ctctgtgaca ccaacacctg taaatttgat ggggaatgtt taagaattgg      660

agacactgtg acttgcgtct gtcagttcaa gtgcaacaat gactatgtgc ctgtgtgtgg      720

ctccaatggg gagagctacc agaatgagtg ttacctgcga caggctgcat gcaaacagca      780

gagtgagata cttgtggtgt cagaaggatc atgtgccaca gatgcaggat caggatctgg      840

agatggagtc catgaaggct ctggagaaac tagtcaaaag gagacatcca cctgtgatat      900

ttgccagttt ggtgcagaat gtgacgaaga tgccgaggat gtctggtgtg tgtgtaatat      960

tgactgttct caaaccaact tcaatcccct ctgcgcttct gatgggaaat cttatgataa     1020

tgcatgccaa atcaaagaag catcgtgtca gaaacaggag aaaattgaag tcatgtcttt     1080

gggtcgatgt caagataaca caactacaac tactaagtct gaagatgggc attatgcaag     1140

aacagattat gcagagaatg ctaacaaatt agaagaaagt gccagagaac accacatacc     1200

ttgtccggaa cattacaatg gcttctgcat gcatgggaag tgtgagcatt ctatcaatat     1260

gcaggagcca tcttgcaggt gtgatgctgg ttatactgga caacactgtg aaaaaaagga     1320

ctacagtgtt ctatacgttg ttcccggtcc tgtacgattt cagtatgtct taatcgcagc     1380

tgtgattgga acaattcaga ttgctgtcat ctgtgtggtg gtcctctgca tcacaaggaa     1440

atgccccaga agcaacagaa ttcacagaca gaagcaaaat acagggcact acagttcaga     1500

caatacaaca agagcgtcca cgaggttaat ctaaagggag catgtttcac agtggctgga     1560

ctaccgagag cttggactac acaatacagt attatagaca aaagaataag acaagagatc     1620

tacacatgtt gccttgcatt tgtggtaatc tacaccaatg aaaacatgta ctacagctat     1680

atttgattat gtatggatat atttgaaata gtatacattg tcttgatgtt ttttctgtaa     1740

tgtaaataaa ctatttatat cacacaatat agttttttct ttcccatgta tttgttatat     1800

ataataaata ctcagtgatg agaaaaaatt ggcattctta aatttgcggt atctcataac     1860

tgtaaatata atcagactag tacaatctgt acagctacca atatttcatg tttcttctca     1920

tcttgagaca gcacattagt tcgtacagga ctcagtggct aggttttgaa tgattccaag     1980

atcaagggaa atgatggtta ttggaaaaga gaaaaaataa tttactttat atcgagtgag     2040

gataaaatat ttccgatctt tgaatcatct ctatttcatc aactttcttc cctggtcttc     2100

cattttcatc cctagagcag aaaaatctct ggcatataaa ctaaataaaa gaagaagggg     2160

agggaaagtg ttttataact cataaaggag agggaaagaa aatattggtt tttattgggg     2220

aagtagctta gaatccccca gttaagtgca tatatctgaa cttactgaac aagttacata     2280

ctaggtatac acagagtggc aaaatatatt ccatttaggt gggtggaatt accaggggaa     2340

aaatgtaata acaccactag atgtgaaaca ccaaaatcgt gaattctcaa aagcaccata     2400

caatatgtat agtatatagt tctttgaaaa gaagttagaa tcacaaccaa taccccatga     2460

atagctttgt ggctaatgca gcaccataat ttgtaatgga actaagatga tgatgacgat     2520

atttcatgaa aacagagaga tgttttgagc atatttatgt ggtgaggtaa gaaagaaaat     2580

taatcctata gcatctgaaa gacctcactg ggaagttggt atggattttt gtttgatttg     2640

tgcatacaaa taggtatcac aacttgatct ggaaaaaata agctgtgaaa attctcaagg     2700

aataagatga aaataaatca attattatca tttagctctg caaagctttc catggctaac     2760

acagtaaatt taaataaagc tctctttgtc tccttcaaaa aaaaaaaaaa aaaaaa         2816


<210>  988
<211>  2738
<212>  DNA
<213>  homo sapiens

<400>  988
agagtgccga gcagcgcggt gggtgcggct gtgagacggc aggagacttc tgccccgcgg       60

tgcacgcgac cctcgagacg acagcgcggc tactgccagc agcgaaggcg cctcccgcgg      120

agcgccccga cggcgcccgc tcgcccatgc cgagctgagc gcggcagcgg cggcgggatg      180

ctggcgctgc tggccgccag cgtggcgctc gccgtggccg ctggggccca ggacagcccg      240

gcgcccggta gccgcttcgt gtgcacggca ctgcccccag aggcggtgca cgccggctgc      300

ccgctgcccg cgatgcccat gcagggcggc gcgcagagtc ccgaggagga gctgagggcc      360

gcggtgctgc agctgcgcga gaccgtcgtg cagcagaagg agacgctggg cgcgcagcgc      420

gaggccatcc gcgagctcac gggcaagcta gcgcgctgcg aggggctggc gggcggcaag      480

gcgcgcggcg cgggggccac gggcaaggac actatgggcg acctgccgcg ggaccccggc      540

cacgtcgtgg agcagctcag ccgctcgctg cagaccctca aggaccgcct ggagagcctc      600

gagcaccagc tcagagcaaa cgtgtccaat gctgggctgc ccggcgactt ccgcgaggtg      660

ctccagcagc ggctggggga gctggagagg cagcttctgc gcaaggtggc agagctggag      720

gacgagaagt ccctgctgca caatgagacc tcggctcacc ggcagaagac cgagagcacc      780

ctgaacgcgc tgctgcagag ggtcaccgag ctggagcgag gcaatagcgc ctttaagtca      840

ccagatgcgt tcaaggtgtc cctcccactc cgcacaaact acctatacgg caagatcaag      900

aagacgctgc ctgagctgta cgccttcacc atctgcctgt ggctgcggtc cagcgcctca      960

ccaggcattg gcaccccctt ctcctatgcg gtgccagggc aggccaacga gatcgtgctg     1020

atcgagtggg gcaacaaccc catcgagctg ctcatcaacg acaaggttgc gcagctgccc     1080

ctgtttgtca gtgacggcaa gtggcaccac atctgtgtca cctggacgac acgggatggc     1140

atgtgggagg cattccagga cggagagaag ctgggcactg gggagaacct ggccccctgg     1200

caccccatca agcccggggg cgtgctgatc cttggacaag agcaggacac cgtggggggt     1260

aggtttgatg ccactcaggc atttgtcggg gagctcagcc agttcaacat atgggaccgc     1320

gtccttcgcg cacaagaaat tgtcaacatc gccaactgct ccacaaacat gccgggcaac     1380

atcatcccgt gggtggacaa taacgtcgat gtgttcggag gggcctccaa gtggcccgtg     1440

gagacgtgtg aggagcgtct ccttgacttg tagccgcctt ctcctctgtc caggaggccg     1500

ggatcaggct gttgccatgg aagttcaggg ccatagactg ccccacttaa actcttgtca     1560

gtctgggctc agggttccca gagctcattc cccaggaatc tctaagacca gggctggggc     1620

agtgtctgtc actggcttgt ttgttcccta ccaatattct gttgctgttt gaagtagtgc     1680

cagggtcccc tgggaagatg cccccaagac acctgcccca agtgggtgga tatctgcctt     1740

cctgctgcaa gtggaggcag gtccagcagc ccctcttcag agcccctgta aatgctatcg     1800

cagcctgagt cctgccgcct tccagttcct tggtgtcccg tgcacccctt ctgtctgtcc     1860

cctttcatgg ctgtgcagcc gtcccgctgg agtggccatg tcccttgtgc attgagtgca     1920

tccccgctgg tgactaagct cgcagcaagc ggctaccccc cgatctgcaa aagggcctct     1980

ccctttgtgt tctatacatt gtgaatcttc ccgtctgaag aacgcccagc ctgcccagac     2040

aaagccccgc cttccccaaa gcagaggggc tgtctgtgtc tccagaaagg ggacatcggg     2100

ggggaggggg gctcagaaag gagaagggct gtgatctccg gtcccttccc ccatcatcct     2160

tccttagact gatgctttga ctgaatcatc actagctatg gcattaaaag gcctctcttc     2220

tcatctggtg ccaaaggttc cgttgcagct ttttacaacc atccggtgtg gtttggagga     2280

tttgtttttt ttttttccca acagaaaaga acagccatta gaagaaggct cccattttct     2340

gatgttccgc cccactgtga agagtgtgct cgttttaaat tcatgttgat tcttgtaagc     2400

actggactgt cttcatcaag tatttcccta cagaactcct caagaaaaca gagatcattt     2460

ggctagagat tgtctgagtg actccaagct actcactgta ttggacggga gtagtaattt     2520

attttaaaga taaagtgact aagtggggaa atttataaag ctaaatatta tatattttat     2580

ttttcataca tgtttgaagt gcaaatctgt ggatattcca tttgtaggac caagtcgaca     2640

tgcccatcct gacattgtat gctacgagaa ctcttctgat gatggaattt cgattaaagt     2700

gcactgaaag atgaaaaaaa aaaaaaaaaa aaaaaaaa                             2738


<210>  989
<211>  1272
<212>  DNA
<213>  homo sapiens

<400>  989
gggcggggcg ggtgagtggg cggggcctcg gcgtggtagg cgcgctgcgt aaagaggcct       60

gcagtcccgc ggcgcggggc aggttccggg ctgcttaggt tggcaccggt ccgtggtccc      120

cgggggcgca gtcgcagcgc tcccgccctc caggcgtcag cgagtgcgcg gtccagtgcg      180

gccggaacct ggcgcaactc ctagagcggt ccttggggag acgcgggtcc cagtcctgcg      240

gctcctactg gggagtgcgc tggtcggaag attgctggac tcgctgaaga gagactacgc      300

aggaaagccc cagccaccca tcaaatcaga gagaaggaat ccaccttctt acgctatggc      360

aggtaagaaa gtactcattg tctatgcaca ccaggaaccc aagtctttca acggatcctt      420

gaagaatgtg gctgtagatg aactgagcag gcagggctgc accgtcacag tgtctgattt      480

gtatgccatg aaccttgagc cgagggccac agacaaagat atcactggta ctctttctaa      540

tcctgaggtt ttcaattatg gagtggaaac ccacgaagcc tacaagcaaa ggtctctggc      600

tagcgacatc actgatgagc agaaaaaggt tcgggaggct gacctagtga tatttcagtt      660

cccgctgtac tggttcagcg tgccagccat cctgaagggc tggatggata gggtgctgtg      720

ccagggcttt gcctttgaca tcccaggatt ctacgattcc ggtttgctcc agggtaaact      780

agcgctcctt tccgtaacca cgggaggcac ggccgagatg tacacgaaga caggagtcaa      840

tggagattct cgatacttcc tgtggccact ccagcatggc acattacact tctgtggatt      900

taaagtcctt gcccctcaga tcagctttgc tcctgaaatt gcatccgaag aagaaagaaa      960

ggggatggtg gctgcgtggt cccagaggct gcagaccatc tggaaggaag agcccatccc     1020

ctgcacagcc cactggcact tcgggcaata actctgtggc acgtgggcat cacgtaagca     1080

gcacactagg aggcccaggc gcaggcaaag agaagatggt gctgtcatga aataaaatta     1140

caacatagct acctggggat acttttttct ttctgttttt tgtttgtttt taattttagc     1200

tttaaggagc acatggccag tactgtttca ggggaatatt gggtggcgct ggggtttggg     1260

cttctattga tc                                                         1272


<210>  990
<211>  3230
<212>  DNA
<213>  homo sapiens

<400>  990
agcagtgttc tcttcgtccc cctcccccaa actgaggatt gggcaatacc acagaacctc       60

aggaaagggg ggaagagcga gcttcggccc cactaatggg ggagtgggcg gaggctggat      120

ttcccacctc ggctgcacct gggcactgga ggctgaagag gaaagtgaga atctgaagtt      180

ttgagacctc tgactggcca ggaatagctc ctggggcggg gggcaaggat gggaccatag      240

gcggaaagag tctcgcggtc ccccctgctt ctggcgcggg tccctgcgcc cggttgtgga      300

gcgtctcgcg cggggagggg gcggggggaa cggcagctcg cggtgttgtt cactcgcgcg      360

tcgagcacac ggtgggtccg gcggcgggtt ggcgccccag gcggcgttcc ctgtggcctg      420

gcgcctgggc cgctgccctg agcgggttcc gccccagagc ccgaccctcc tgggggctct      480

aggcggagtc ccgcgagccg agggggaccg gcgaccgctg ccgaagcatg aagaaggggt      540

aaggcgtgag cccccaagat ttcacgcatg ccccctagct tcggtactct gacaccttct      600

cttgcacttg cggatgatga actggaataa cgatgaaaga aagcacatcc gatctcaaca      660

ttcacgtcct gccctataac cgattaatta attgatcccc agctagacta gtgttggaga      720

aatcagcatg ttaaaacaac tgttgatgat agctgttgga gtaaagttgc agtggaagct      780

atggctgcaa aatcgttaaa atcttcaagg tgaactggca caaaggttaa tctcaagatg      840

ccgctagtga aaagaaacat cgatcctagg cacttgtgcc acacagcact gcctagaggc      900

attaagaatg aactggaatg tgtaaccaat atttccttgg caaatataat tagacaacta      960

agtagcctaa gtaaatatgc tgaagatata tttggagaat tattcaatga agcacatagt     1020

ttttccttca gagtcaactc attgcaagaa cgtgtggacc gtttatctgt tagtgttaca     1080

cagcttgatc caaaggaaga agaattgtct ttgcaagata taacaatgag gaaagctttc     1140

cgaagttcta caattcaaga ccagcagctt ttcgatcgca agactttgcc tattccatta     1200

caggagacgt acgatgtttg tgaacagcct ccacctctca atatactcac tccttataga     1260

gatgatggta aagaaggtct gaagttttat accaatcctt cgtatttctt tgatctatgg     1320

aaagaaaaaa tgttgcaaga tacagaggat aagaggaagg aaaagaggaa gcagaagcag     1380

aaaaatctag atcgtcctca tgaaccagaa aaagtgccaa gagcacctca tgacaggcgg     1440

cgagaatggc agaagctggc ccaaggtcca gagctggctg aagatgatgc taatctctta     1500

cataagcata ttgaagttgc taatggccca gcctctcatt ttgaaacaag acctcagaca     1560

tacgtggatc atatggatgg atcttactca ctttctgcct tgccatttag tcagatgagt     1620

gagcttctga ctagagctga ggaaagggta ttagtcagac cacatgaacc acctccacct     1680

ccaccaatgc atggagcagg agatgcaaaa ccgataccca cctgtatcag ttctgctaca     1740

ggtttgatag aaaatcgccc tcagtcacca gctacaggca gaacacctgt gtttgtgagc     1800

cccactcccc cacctcctcc accacctctt ccatctgcct tgtcaacttc ctcattaaga     1860

gcttcaatga cttcaactcc tccccctcca gtacctcccc cacctccacc tccagccact     1920

gctttgcaag ctccagcagt accaccacct ccagctcctc ttcagattgc ccctggagtt     1980

cttcacccag ctcctcctcc aattgcacct cctctagtac agccctctcc accagtagct     2040

agagctgccc cagtatgtga gactgtacca gttcatccac tcccacaagg tgaagttcag     2100

gggctgcctc cacccccacc accgcctcct ctgcctccac ctggcattcg accatcatca     2160

cctgtcacag ttacagctct tgctcatcct ccctctgggc tacatccaac tccatctact     2220

gccccaggtc cccatgttcc attaatgcct ccatctcctc catcacaagt tatacctgct     2280

tctgagccaa agcgccatcc atcaacccta cctgtaatca gtgatgccag gagtgtgcta     2340

ctggaagcaa tacgaaaagg tattcagcta cgcaaagtag aagagcagcg tgaacaggaa     2400

gctaagcatg aacgcattga aaacgatgtt gccaccatcc tgtctcgccg tattgctgtt     2460

gaatatagtg attcggaaga tgattcagaa tttgatgaag tagattggtt ggagtaagaa     2520

aaatgcattg ataaatatta caaaactgaa tgcaaatgtc ctttgtggtg cttgttcctt     2580

gaaaatgttt ggtcattcta gtgttttgct ttcttttcct tataataaat gacccttttc     2640

ctccataact tttgatttct aaggaaaata ttagcataca tttcaaacta aatgttttac     2700

agtggcttat cttttttttc cccctgaaaa gactaatttg gtcaaataaa ccactaagta     2760

ttaagcatgg acagctgttg ttagagtagc agattcagtt ttttgatata tcttaattgt     2820

gtactttgtg aattttaatt taaagaaagc aactgaaatt gaaatcttga gggcagctgt     2880

gtctactaat gagccttatt ccatttcctg atgttttaaa agaagaaaca ctgccttgat     2940

tatacgaata cactcagaaa gtacatttag cttgtagtgt tgaattctct taaaggaatg     3000

cttgaatttt ttcattattg ttttattgtt tttatatact tgccttattt gaatgtttag     3060

cagtatcccc ttcccactta tatattgtgt gatatgattt tgcttgccta taggagttaa     3120

aaacttttcc atgtgaaata ctctgactta aacatacatg taacttacat aactgttaag     3180

aataacagtc tgatttaata aatggttcat tttaaaagtt aaaaaaaaaa                3230


<210>  991
<211>  3132
<212>  DNA
<213>  homo sapiens

<400>  991
agcagtgttc tcttcgtccc cctcccccaa actgaggatt gggcaatacc acagaacctc       60

aggaaagggg ggaagagcga gcttcggccc cactaatggg ggagtgggcg gaggctggat      120

ttcccacctc ggctgcacct gggcactgga ggctgaagag gaaagtgaga atctgaagtt      180

ttgagacctc tgactggcca ggaatagctc ctggggcggg gggcaaggat gggaccatag      240

gcggaaagag tctcgcggtc ccccctgctt ctggcgcggg tccctgcgcc cggttgtgga      300

gcgtctcgcg cggggagggg gcggggggaa cggcagctcg cggtgttgtt cactcgcgcg      360

tcgagcacac ggtgggtccg gcggcgggtt ggcgccccag gcggcgttcc ctgtggcctg      420

gcgcctgggc cgctgccctg agcgggttcc gccccagagc ccgaccctcc tgggggctct      480

aggcggagtc ccgcgagccg agggggaccg gcgaccgctg ccgaagcatg aagaaggggt      540

aaggcgtgag cccccaagat ttcacgcatg ccccctagct tcggtactct gacaccttct      600

cttgcacttg cggatgatga actggaataa cgatgaaaga aagcacatcc gatctcaaca      660

ttcacgtcct gccctataac cgattaatta attgatcccc agctagacta ggtgaactgg      720

cacaaaggtt aatctcaaga tgccgctagt gaaaagaaac atcgatccta ggcacttgtg      780

ccacacagca ctgcctagag gcattaagaa tgaactggaa tgtgtaacca atatttcctt      840

ggcaaatata attagacaac taagtagcct aagtaaatat gctgaagata tatttggaga      900

attattcaat gaagcacata gtttttcctt cagagtcaac tcattgcaag aacgtgtgga      960

ccgtttatct gttagtgtta cacagcttga tccaaaggaa gaagaattgt ctttgcaaga     1020

tataacaatg aggaaagctt tccgaagttc tacaattcaa gaccagcagc ttttcgatcg     1080

caagactttg cctattccat tacaggagac gtacgatgtt tgtgaacagc ctccacctct     1140

caatatactc actccttata gagatgatgg taaagaaggt ctgaagtttt ataccaatcc     1200

ttcgtatttc tttgatctat ggaaagaaaa aatgttgcaa gatacagagg ataagaggaa     1260

ggaaaagagg aagcagaagc agaaaaatct agatcgtcct catgaaccag aaaaagtgcc     1320

aagagcacct catgacaggc ggcgagaatg gcagaagctg gcccaaggtc cagagctggc     1380

tgaagatgat gctaatctct tacataagca tattgaagtt gctaatggcc cagcctctca     1440

ttttgaaaca agacctcaga catacgtgga tcatatggat ggatcttact cactttctgc     1500

cttgccattt agtcagatga gtgagcttct gactagagct gaggaaaggg tattagtcag     1560

accacatgaa ccacctccac ctccaccaat gcatggagca ggagatgcaa aaccgatacc     1620

cacctgtatc agttctgcta caggtttgat agaaaatcgc cctcagtcac cagctacagg     1680

cagaacacct gtgtttgtga gccccactcc cccacctcct ccaccacctc ttccatctgc     1740

cttgtcaact tcctcattaa gagcttcaat gacttcaact cctccccctc cagtacctcc     1800

cccacctcca cctccagcca ctgctttgca agctccagca gtaccaccac ctccagctcc     1860

tcttcagatt gcccctggag ttcttcaccc agctcctcct ccaattgcac ctcctctagt     1920

acagccctct ccaccagtag ctagagctgc cccagtatgt gagactgtac cagttcatcc     1980

actcccacaa ggtgaagttc aggggctgcc tccaccccca ccaccgcctc ctctgcctcc     2040

acctggcatt cgaccatcat cacctgtcac agttacagct cttgctcatc ctccctctgg     2100

gctacatcca actccatcta ctgccccagg tccccatgtt ccattaatgc ctccatctcc     2160

tccatcacaa gttatacctg cttctgagcc aaagcgccat ccatcaaccc tacctgtaat     2220

cagtgatgcc aggagtgtgc tactggaagc aatacgaaaa ggtattcagc tacgcaaagt     2280

agaagagcag cgtgaacagg aagctaagca tgaacgcatt gaaaacgatg ttgccaccat     2340

cctgtctcgc cgtattgctg ttgaatatag tgattcggaa gatgattcag aatttgatga     2400

agtagattgg ttggagtaag aaaaatgcat tgataaatat tacaaaactg aatgcaaatg     2460

tcctttgtgg tgcttgttcc ttgaaaatgt ttggtcattc tagtgttttg ctttcttttc     2520

cttataataa atgacccttt tcctccataa cttttgattt ctaaggaaaa tattagcata     2580

catttcaaac taaatgtttt acagtggctt atcttttttt tccccctgaa aagactaatt     2640

tggtcaaata aaccactaag tattaagcat ggacagctgt tgttagagta gcagattcag     2700

ttttttgata tatcttaatt gtgtactttg tgaattttaa tttaaagaaa gcaactgaaa     2760

ttgaaatctt gagggcagct gtgtctacta atgagcctta ttccatttcc tgatgtttta     2820

aaagaagaaa cactgccttg attatacgaa tacactcaga aagtacattt agcttgtagt     2880

gttgaattct cttaaaggaa tgcttgaatt ttttcattat tgttttattg tttttatata     2940

cttgccttat ttgaatgttt agcagtatcc ccttcccact tatatattgt gtgatatgat     3000

tttgcttgcc tataggagtt aaaaactttt ccatgtgaaa tactctgact taaacataca     3060

tgtaacttac ataactgtta agaataacag tctgatttaa taaatggttc attttaaaag     3120

ttaaaaaaaa aa                                                         3132


<210>  992
<211>  2864
<212>  DNA
<213>  homo sapiens

<400>  992
gatgcagcgt agctcttagg gggaggtgtg agtccttgga aagctcacaa gaatttcaga       60

ggggcccgag atgcgagtcg gactcccttc cgaggcgtcg tcttgcccat ggtcagcgcg      120

ggggccgcgg gacccgccag agcgcaggcg gagtgggctg gcgcacgtgg tagcgaggga      180

gttgggtctc caggttgtgc gaggagcaaa tgatgaccgc caaggccgta gacaaaatcc      240

cagtaactct cagtggtttt gtgcaccagc tgtctgacaa catctacccg gtggaggacc      300

tcgccgccac gtcggtgacc atctttccca atgccgaact gggaggcccc tttgaccaga      360

tgaacggagt ggccggagat ggcatgatca acattgacat gactggagag aagaggtcgt      420

tggatctccc atatcccagc agctttgctc ccgtctctgc acctagaaac cagaccttca      480

cttacatggg caagttctcc attgaccctc agtaccctgg tgccagctgc tacccagaag      540

gcataatcaa tattgtgagt gcaggcatct tgcaaggggt cacttcccca gcttcaacca      600

cagcctcatc cagcgtcacc tctgcctccc ccaacccact ggccacagga cccctgggtg      660

tgtgcaccat gtcccagacc cagcctgacc tggaccacct gtactctccg ccaccgcctc      720

ctcctcctta ttctggctgt gcaggagacc tctaccagga cccttctgcg ttcctgtcag      780

cagccaccac ctccacctct tcctctctgg cctacccacc acctccttcc tatccatccc      840

ccaagccagc cacggaccca ggtctcttcc caatgatccc agactatcct ggattctttc      900

catctcagtg ccagagagac ctacatggta cagctggccc agaccgtaag ccctttccct      960

gcccactgga caccctgcgg gtgccccctc cactcactcc actctctaca atccgtaact     1020

ttaccctggg gggccccagt gctggggtga ccggaccagg ggccagtgga ggcagcgagg     1080

gaccccggct gcctggtagc agctcagcag cagcagcagc cgccgccgcc gccgcctata     1140

acccacacca cctgccactg cggcccattc tgaggcctcg caagtacccc aacagaccca     1200

gcaagacgcc ggtgcacgag aggccctacc cgtgcccagc agaaggctgc gaccggcggt     1260

tctcccgctc tgacgagctg acacggcaca tccgaatcca cactgggcat aagcccttcc     1320

agtgtcggat ctgcatgcgc aacttcagcc gcagtgacca cctcaccacc catatccgca     1380

cccacaccgg tgagaagccc ttcgcctgtg actactgtgg ccgaaagttt gcccggagtg     1440

atgagaggaa gcgccacacc aagatccacc tgagacagaa agagcggaaa agcagtgccc     1500

cctctgcatc ggtgccagcc ccctctacag cctcctgctc tgggggcgtg cagcctgggg     1560

gtaccctgtg cagcagtaac agcagcagtc ttggcggagg gccgctcgcc ccttgctcct     1620

ctcggacccg gacaccttga gatgagactc aggctgatac accagctccc aaaggtcccg     1680

gaggcccttt gtccactgga gctgcacaac aaacactacc accctttcct gtccctctct     1740

ccctttgttg ggcaaagggc tttggtggag ctagcactgc cccctttcca cctagaagca     1800

ggttcttcct aaaacttagc ccattctagt ctctcttagg tgagttgact atcaacccaa     1860

ggcaaagggg aggctcagaa ggaggtggtg tggggacccc tggccaagag ggctgaggtc     1920

tgaccctgct ttaaagggtt gtttgactag gttttgctac cccacttccc cttattttga     1980

cccatcacag gtttttgacc ctggatgtca gagttgatct aagacgtttt ctacaatagg     2040

ttgggagatg ctgatccctt caagtgggga cagcaaaaag acaagcaaaa ctgatgtgca     2100

ctttatggct tgggactgat ttgggggaca ttgtacagtg agtgaagtat agcctttatg     2160

ccacactctg tggccctaaa atggtgaatc agagcatatc tagttgtctc aacccttgaa     2220

gcaatatgta ttataaactc agagaacaga agtgcaatgt gatgggagga acatagcaat     2280

atctgctcct tttcgagttg tttgagaaat gtaggctatt ttttcagtgt atatccactc     2340

agattttgtg tatttttgat gtacactgtt ctctaaattc tgaatctttg ggaaaaaatg     2400

taaagcattt atgatctcag aggttaactt atttaagggg gatgtacata tattctctga     2460

aactaggatg catgcaattg tgttggaagt gtccttggtg ccttgtgtga tgtagacaat     2520

gttacaaggt ctgcatgtaa atgggttgcc ttattatgga gaaaaaaatc actccctgag     2580

tttagtatgg ctgtatattt ctgcctatta atatttggaa ttttttttag aaagtatatt     2640

tttgtatgct ttgttttgtg acttaaaagt gttacctttg tagtcaaatt tcagataaga     2700

atgtacataa tgttaccgga gctgatttgt ttggtcatta gctcttaata gttgtgaaaa     2760

aataaatcta ttctaacgca aaaccactaa ctgaagttca gataatggat ggtttgtgac     2820

tatagtgtaa ataaatactt ttcaacaata aaaaaaaaaa aaaa                      2864


<210>  993
<211>  2990
<212>  DNA
<213>  homo sapiens

<400>  993
aactacaaaa ttgaaagtag agaggagggg gcagccaatg gaaaaaaaaa tttgcacagc       60

agccaatcct cctgcggcgt tttgtgcctt tgcccaacag gaaaatgtgt ctcatgcaga      120

ggggcgttac ccagtctcca atgggcggga gccggtggaa cggaggagcc aatgagtgcg      180

agatgttgag tgacagctgt ccaatggagg ccctccgtgc tagtacggct tgcggcttaa      240

gcgccgccgc ggtctgcgga atgtcaacta ttcaacatgg aggcggaggt cgataagctg      300

gaactgatgt tccagaaagc tgagtctgat ctggattaca ttcaatacag gctggaatat      360

gaaatcaaga ctaatcatcc tgattcagca agtgagaaaa atccagttac actcttaaag      420

gaattgtcag tgataaagtc tcgatatcaa actttgtatg cccgctttaa accagttgct      480

gttgagcaga aagagagtaa gagccgcatt tgtgctactg tgaaaaagac tatgaatatg      540

atacaaaaac tacagaagca aacagacctg gagctgtcac cactgactaa agaagagaaa      600

actgcggcag agcaattcaa atttcacatg ccagatttat gaagaaatgg acttggaaag      660

gaaattctaa cagagaagag cttaattccg gagaaattta ggaagatgtc ttgttaaccc      720

ttgatgtcta gagattgggg gctggtgaag ggggtttggc ttcaatgact ggataatgat      780

atctttcatg agagagatta taagaagaag ggcagataat atatgaataa agttcagcca      840

aaaggatcaa atgagaataa aacgatttaa atatatgtac acacgcatgc acacacacac      900

ttagtcttgt aatttcaggc cagaaattct caacactatt ttgcatctgt tttctttttc      960

taagtcatga taatatagat gttctggtct atcataaaag aatgtttatg tacatttcag     1020

tcattcggta tgtggctttg taaattaaag tataggcaaa acatttgtgt tatacatgat     1080

atataatttc attttgtaaa tgttgattgc acatgtggtc acattattgt tgagactgct     1140

tttatgtgac ctgtagtctc ccacagaacc taaagtaata agctggcttt tctgtgatag     1200

ccacgtttgc gtatttcttt ccctatttcc cttgcctgct aatgttgaac agcatgaact     1260

tgctttctga tgctgtttta gactgtccct gttgtatctc aataatatct ttgttttcct     1320

tcagccttta ttactataat tgttcattct acatgaaagc taggaaactg aaattagaag     1380

agcacttatc tgctacttgc cagttttgcg tgagtgtgtt atatgtatgt gtcaatttcc     1440

ctttaaaata actatttatt ttaaaataac tattggcaat aaggaaactg ttcaaagtag     1500

aggcagatct tgatagaaag atgttaatca cagggttgtt tataatagca atatacatac     1560

acatttggct agtactaggt gaataggaaa ataaatcatg ctgtatgtat acaataagag     1620

gtcaagttgc caataaatta ttactgttaa tgttctggga aatgctgaaa ctatgctaag     1680

tgggggagag ggaaagcagg tattgcagtt ttgtagtgaa gattgggctt tggagtcata     1740

tctgagatgt aagtagcagc ttttaaattc tagctatgac cctgtgcaga tcacttaact     1800

tttgagtgtc aggatgtttg gaaggacaag acaggaaagt gttttaatac agggttcagt     1860

atttagtaag ccttcaataa gtgatattac atacatgtaa taaaaactaa gcattgaaag     1920

gactaggaaa aatgcatcaa atgttagttc tgcaggttat agaattatac ttttatgtaa     1980

ttttaaaatt tcagttatga acatgtttgt ccattaacaa acttataata gctgaaaaac     2040

agggttgtga gaacagcttc agttaaaatt gtcctgtcta gtttgaatat ttcaagaaca     2100

gaaagccttt tttttttttt tttttttttt gagacggagt ctcactctgt tgcccaggct     2160

ggaatgcagt ggtacgctct cagctcactg caacctccac ctcccaggtt caagcagttc     2220

tctgccccac cctcccgagt agctgggatt acaggcgccc gccaccacgc ccggctattt     2280

ttttgtattt ttagtagaga tggggcttca ccatcttgac caggctggtc tttaactcct     2340

gatggtgatc cacccacctc ggcctcccaa agtgctggga ttacaggcat gagctaccgt     2400

gcctggcccc ctttttttta attacagaga aataagttac accttagtat cagatattaa     2460

ttttcttcag tgttcaggca attagtattt agaaagctct tgtcatgaga tggctctggg     2520

atgtgatgat gattgttggg attgaaaaaa cggtagtatc atggagagat cataataaat     2580

tcttagtatt aaaagtggtt ttgctttcag ttagggagaa aaattagatt gtactatttt     2640

tcctctatga tttccttcag ttatcttcca aatgttgttt tttccccaca gcccccttaa     2700

cattgttctc tatgcacttc tcaatacatt ttcatttgtt tctcaagcct ctttgtggat     2760

gactcctaaa tataacttct tccactagct ctagatccgt atttccaata aaatccccta     2820

cctgaatatt caagttaaac atgtccagaa tacttactga ttttattgtt aatagccact     2880

attctgttgt ctggaattaa aacctgtata actaatttgc atccctttat cttcttagtc     2940

aataaaacct acaatcctct ttctaaaatg gtaaaaaaaa aaaaaaaaaa                2990


<210>  994
<211>  7115
<212>  DNA
<213>  homo sapiens

<400>  994
ctccctctcc tatcggagca caatgaaagc ctgtgtatcg ccgtgactcc gggcgcgagc       60

cagtgtcagc aaagcggcta acaacagacg agaaagagaa aggaaaatac aagctacttt      120

ttttttccat ctataaagcg gagcaaatac aggagataga accagattgc ttattgcgag      180

tccagaccct cagatccact ggccggggat ggaatgtaca aaagtggaca gaaaagtggc      240

tggacatgac tcggtgcaat ttgctggaag tttgtaagtt tgaccatcgt ttgtaaatta      300

ctctcggaag agtttgtctc tcttgatact gtattagaat agagccgggg gtgaggaata      360

gaaacgtaag cgggaaagaa aaaaatgtgt tgaaggatct ctctcagtgg ctagcgactt      420

aagattgctt ttcatttaag gctaggaaac cttagaggga gtgaggattt taccggtgat      480

tggattagct gaagaaaaaa gcatggtcca aaagtccaat tactgacatt gttaacagtt      540

gaaaagctgt ctccctcttt tgggagaaga caacatccta cagtacccca aagaggagaa      600

aacaccggag cgaaaggaaa gggaggaaaa attaaaagcc aaaagacagt ctcccttgat      660

ttttgcacat tttgaacagt gacttaaaca tcttctgaaa cagcactgtt ttgttttgtt      720

ttggtttttt atttaacctg aggaaaagtc aaggctgctg gttacataga catggtagaa      780

atgtgtttct ctgcagaaac atccccataa agaattgtcg gaaacaacta ggtgaggggg      840

agtcctctct attaatacct ctctcaatac cttttgctgt gtgtttctgt ctcttgctgg      900

acaatccctg aattcttgat ctaaccccca gatcgtgtgt ttacaaagta cctagtggct      960

cttgtcagct tggtggagga aaaaaaatcc accaactctg tccaacttct ccagagctgt     1020

caaatgcaat tagagtaagt taatcagggt ttgtttccaa cttatcctcc ccccagttgg     1080

tttctattct ttctccccac cctcttttta ctaactcccc tcccccacaa cttctccacg     1140

gctcccccac aacctctgaa gacctctatt catgtggccc tgaacactga gctcacattg     1200

tcaaaaacag acttgcctgc aatagccagc agtagcctct ttccacctca ccatcccaga     1260

ggcagcaatc attgtgtccg gtaagatggg ggacacagcg cccccgcagg cccccgcagg     1320

agggctaggg ggggcctctg gggcggggct ccttggaggg ggctcagtca ccccgagagt     1380

gcacagtgct atcgtggagc gcctccgggc tcggatcgct gtctgccgcc aacaccacct     1440

gagctgtgaa ggacgatatg aacgaggtag ggccgagagc tcagaccggg aaagagaaag     1500

caccttgcag ctcctgagcc ttgtacagca tggccagggg gcaaggaaag ctggcaaaca     1560

caccaaggcc accgccactg ctgccaccac tacagcccct ccaccgcccc ctgctgcccc     1620

tcctgcggcc tcccaagcag cagcaacagc agccccaccg cccccaccag actatcacca     1680

tcaccaccag cagcacctgc tgaacagtag caataatggt ggcagtggtg ggataaacgg     1740

agagcagcag ccgcccgctt caaccccagg ggaccagagg aactcagccc tgattgcgct     1800

ccagggttcc ttgaaaagaa aacaggtagt taacctatct cctgccaaca gcaagcgacc     1860

caatggcttt gtggacaact catttcttga tatcaaaaga attcgtgttg gggagaatct     1920

ctctgcagga caaggtggcc tccaaataaa caatggacaa agtcagatta tgtcagggac     1980

cttgcctatg agccaagcac ccctgcgaaa gactaacact ctgccatccc atacacattc     2040

tcctggcaat ggcctgttta acatgggctt aaaggaggta aagaaggagc caggagagac     2100

tctgtcttgc agtaagcaca tggatggcca aatgacccaa gagaatattt ttcctaatag     2160

gtacggagac gaccctggag aacaactgat ggatcctgag ctgcaggaac tgttcaatga     2220

actgaccaac atatctgtgc ctcccatgag tgaccttgaa ctggagaaca tgatcaatgc     2280

caccataaag caggatgacc catttaacat tgacttgggt cagcaaagcc agaggagcac     2340

acctaggccc tccttaccca tggagaaaat agtgatcaaa agtgaatact caccgggctt     2400

gactcagggc ccctcaggct ctcctcagct gaggccccca tcagctggcc ccgcattctc     2460

catggccaac tctgccctct ccacttcgtc tccaatccct tcagtccctc agagccaggc     2520

tcagcctcag acaggctccg gagcaagccg ggccttgcca agctggcagg aagtatccca     2580

tgcccagcag ctcaaacaga tagctgctaa tcgtcagcag catgcccgga tgcagcagca     2640

ccagcagcag caccagccta ccaactggtc agccttgccc tcttctgctg gaccatcacc     2700

aggtccattt gggcaggaga aaatccccag cccttctttt ggtcagcaga cattcagccc     2760

acagagctcc cccatgcctg gggtagctgg cggcagcggc cagtcgaaag taatggctaa     2820

ctacatgtac aaggccggcc cctcagccca gggtgggcac ctagatgtcc tcatgcagca     2880

aaagcctcag gatctcagtc gaagttttat taacaacccg cacccagcca tggagccccg     2940

tcagggcaac accaagcctt tgtttcattt taactcagat caagcgaacc agcagatgcc     3000

ttctgttttg ccttcccaga acaagccttc tctcctacac tacacccaac agcaacagca     3060

gcaacagcag cagcagcagc agcagcagca gcagcagcag cagcaacagc agcagcagca     3120

gcaacagcaa cagcaacagc aacagcagag ttcaatttca gctcaacaac agcaacagca     3180

gcagagctca atttcagccc aacagcagca gcagcagcaa caacagcagc agcagcagca     3240

acaacaacag caacaacagc agcagcagca gcagcaacaa ccatcttctc agcctgccca     3300

atctctacca agccagcctt tgctaaggtc acctttgcca cttcagcaaa agctcctact     3360

tcagcaaatg cagaatcagc ccattgcagg aatgggatac caagtctccc aacaacagag     3420

acaggatcaa cactctgtgg taggccagaa cacaggcccc agtccaagtc ctaacccctg     3480

ctcaaatcca aacactggaa gtggttacat gaactcccag caatcactgt tgaatcagca     3540

attgatggga aagaagcaga ctctacagag gcagatcatg gagcagaaac agcaacttct     3600

tctccagcag cagatgctgg ctgacgcgga gaaaattgct ccacaagatc agataaaccg     3660

acatttgtca aggccacctc cagattataa agaccaaaga agaaatgtgg gcaatatgca     3720

accaactgct cagtattctg gtggctcatc cacaataagc ttaaactcta accaggcttt     3780

ggcaaaccca gtttcaacac acaccatttt aactcccaat tccagcctcc tgtctacttc     3840

tcacgggaca agaatgccat cattatctac agcagttcag aatatgggga tgtatggaaa     3900

tctgccttgt aatcaaccta acacatacag tgtcacttca ggaatgaatc aattgaccca     3960

acagagaaac ccaaagcaat tgttagcaaa tcaaaacaac cctatgatgc cacggccacc     4020

taccttaggg ccaagtaata ataacaatgt agccactttt ggagctggat ctgttggtaa     4080

ttcacaacaa ttgagaccaa atttaaccca tagtatggca agcatgccac cacagagaac     4140

atcaaacgta atgatcacat ccaacacaac tgcaccaaac tgggcctctc aagaaggaac     4200

aagcaaacag caagaagccc tgacgtctgc aggagtccgc ttccccacag gtacacctgc     4260

agcctatacc ccaaatcagt cactgcaaca ggcagtaggt agccagcaat tttcccagag     4320

ggcagtggct cctcctaacc agttaacacc agcagtgcaa atgagaccca tgaaccaaat     4380

gagccaaaca ctaaatgggc aaaccatggg tcccctcagg ggtctgaatc tcagacccaa     4440

tcagctaagc acacagattt tgcctaattt gaatcagtca ggaacagggt tgaatcagtc     4500

gaggacgggc atcaaccagc caccatccct gacgcccagc aattttcctt cacccaacca     4560

aagttccagg gcttttcaag gaactgacca cagcagtgac ttagcttttg acttcctcag     4620

ccaacaaaat gataacatgg gccctgccct aaacagtgat gctgatttca ttgattcttt     4680

attgaagaca gagcctggta atgatgactg gatgaaagac atcaatcttg atgaaatctt     4740

ggggaacaat tcctaaagaa gaaagggaag acaatttaca aactccaagc actaaaaggc     4800

agtatattac agaaactctg tagaggctga actgttgatg ttcaggtgga ctacatgaag     4860

ataacatgct taaaaatgga aagcagaaag taactgcagt gatgaacatt ttggtccaaa     4920

ttcttgtttt aaatcttaca cctgaaagta aaatattggg atcacttttc cctgtctaaa     4980

ctccaggata cagtatccaa tttatccaaa cagaactgtg gtgtcaatgt gtaattaatt     5040

gtgtaaaata gccttcccaa gtttcttttt ccctggaaaa taaaaaaggt aatagaactt     5100

gtagtttatt taaaccccat gtcatgagga ggtactagtt ccaagcaaca aactccttaa     5160

tttgctctaa tagataggta tggtttaatc tttccattgt gtcttttcat ttaattttcc     5220

tgaagcttgc aggatagatt gaaatgttat aggtttgttt ggagtaacca aacagtatgc     5280

aaattaagaa aaagccagag aacctagaaa acatccagtg gattacagaa tttcttcccc     5340

atattcactc ctcactttta caattttccc acaatcctct acttcagtgg gatgctgtgt     5400

ctagtgatta aacaaaaata tagagctgtg caatttgatt ttggcttcca caacgaatat     5460

ctgaatccat tccaaatgaa attttagata taacaaagac ttgtcctaat catactgaaa     5520

tattggtgca cacctctctg cattagattt cactttttta aaaaacccag tggacattgc     5580

tataaataag atttatttgg ctacaaataa cctgggatgt tgcttattat gattgatgcc     5640

tgctggtttg ttcccaagct gagtgaaatt gaacctcgtc ctccctactc attttgatga     5700

ctgaggctgg tttataagaa aaggaagttt ggagaagaaa accgagatta gaaaatatca     5760

tgttttggtt ggagataaga accagggatg gcaagtacca gtgtgtacaa atgtatttca     5820

cggagtttga aggaacgcat aatcaagagg gaaaacaatt tgtccttcat tggacgtatt     5880

atttggattt gggtgagcaa caaaatggaa tgtggtctgt taggagcatt ctgtttgttc     5940

ttttgtccct gatgtgatga atcattgcca catgctagat ggactcttca tatccaggtt     6000

ttgtccctca gggctgagca ctgtattaaa gagtttttgt tgagtcattt aaccttagtg     6060

tccacatcca gatcagctgt aaaatgggga agacgtgtgc tgatttggaa tgaatgcaaa     6120

atatcactat cattttccta attacagagg agcaaaggtt atcttcagcc ctttcagttc     6180

tatgctcaca tattcaaata tcaaatgtaa tttagctgaa gttatttaat aatcaagtct     6240

ttcaatatct gttcaaagaa aaagaacaca ctttgaaaat tctgcaaagc tgtctcccag     6300

tctttaaaat gtctggaagc actctccttc tttacaatac caacatcact ggcccagaat     6360

cttccctgtg ctagtttgta aatataaata aattacttgt tttgtaaact tttgtaaaga     6420

atattttggt agaaatactt caaacatatt ctttgggtta tatttataca tatgtgaaat     6480

aaatatacta tcaaaaggtt atattttata caaaaagtaa attgctacct tttgtatgct     6540

aatatgcaaa gttttgtata atatgatggt ttatttttag ctctacactt aaaccatagg     6600

tggttgagtg ggaacttttg aaaactatca agaggcttgt tagacaaatt tatattctga     6660

aacctcaata agaaagcatt ccaggtttca atccttgttt tttgtcctgc tcccaaattc     6720

ttttttaaac ccatagttct tgtgtcttat ttgattcttc tgctgtgcac attgtattgg     6780

tccttgttgc atgtagtcta ctgtgtgttt tccgatttta taaggcagca tttctccata     6840

caaaaagaaa aaaaatgatg tacatataaa cgcttttgtt gtatggctcc tccatgttac     6900

tgtatatatc tgccagcact tcccagttac actcctgtga gtcagcttat ttttacccta     6960

acataaatag tatgttttgt agtagttatc aaatttaaga gataaagcaa tcagaatgtt     7020

tggattttct tctatcttaa tgtgaatttc ataattaatg tctatttatt cagctattca     7080

ttaaaataca ggattctttg ggaaaacatg aaaaa                                7115


<210>  995
<211>  3203
<212>  DNA
<213>  homo sapiens

<400>  995
acattaaccc ctgactcaca gctggaccgc cccggcccgc agcgccacgt cccgggtggg       60

gcctgccacg gcaaagcagc agtccggcct cgagcggccc ctcgggggcg gcggggtggg      120

cgccaacagc agtcaggcct gacaagcggc gacctccaag ggtgaggcct ctgcgggccc      180

ccgactcacg cgcgtccggg ctctgcaagc gcggtgggga gcaggctgct gtggtcgcgg      240

ggactgggtt gcggcgcgcc gcgtacggga cggccccaaa ctctcgacgc ccggggcaag      300

acgcccaccc cctgggcgct ctcgctgggc cagaaaggaa gacagaaaag ccgcgggctg      360

actgtggtgg cgctcgcctg cagattgaaa agaaatgctg agaaatacat aaagttttcc      420

tcttctgcct tggatattta taatgggtat cgggaagtct aaaataaatt cctgccctct      480

ttctctctct tggggtaaaa ggcacagtgt ggatacaagt ccaggatatc atgagtcaga      540

ttccaagaag tctgaagatc tatccttgtg taatgttgct gagcacagca atacaacaga      600

ggggccaaca ggaaagcagg agggagctca gagcgtggaa gagatgtttg aagaagaagc      660

tgaagaagag gtgttcctca aatttgtgat attgcatgca gaagatgaca cagatgaagc      720

cctcagagtc cagaatctgc tacaagatga ctttggtatc aaacccggaa taatctttgc      780

tgagatgcca tgtggcagac agcatttaca gaatttagat gatgctgtaa atgggtctgc      840

atggacaatc ttattactga ctgaaaactt tttaagagat acttggtgta atttccagtt      900

ctatacgtcc ctaatgaact ccgttaacag gcagcataaa tacaactctg ttatacccat      960

gcggcccctg aacaatcccc ttccccgaga aaggactccc tttgccctcc aaaccatcaa     1020

tgccttagag gaagaaagtc gtggatttcc tacacaagta gaaagaattt ttcaggagtc     1080

tgtgtataag acacaacaaa ctatatggaa agagacaaga aatatggtac aaagacaatt     1140

tattgcctga gatgaaacat ataacatgtg gctggctctt gttttgtaaa ccaaatgatt     1200

aatcttcact tgagaaagca gtttctagga aatgtttaaa taaaagagag tcttcacctt     1260

aaagaaacct atggagcaca agaaagataa atttctgcag gacagcctat aaaattgtgg     1320

tactttttga tgtttcagta aacttgacat tgtcagagtt tcaaggactt ttctttcaca     1380

attttcctag ttcatggata tgaaaaagga attctcaatc catattcctt gtattgaacc     1440

ttgaacaaaa acttgtatga cagacatttt taaaaatgtg acaacacttt tattctctga     1500

attttgatct caaaggacac agaaaaaaaa tggccccagg agatctgatc acacttcctc     1560

ctgaggcacc tctcatggat gttgcaataa gcattcgggt actatcaccc agaaatatga     1620

attgccagaa tagaacattt agcatgttaa gcgttgatgc atataaaatc agaaatagat     1680

gtgagaatgg tggaactttt taaaagaacc cagtcaaatg tattttctgc tgaaatctgc     1740

atatttggag gcatttccca ccaccgattc acagcccatt tgatagtgtg gtagttaggg     1800

acttcgtgga gtggtgttca gacgtcccct ggggcttaaa tctcttcata ttagtcatca     1860

tttgtaacta tggctttatt tgcagagctt ctaaaaggcg tataactgtg tgagtggcca     1920

gatattcact ttttaaatca aaaacctctc ttatggaagc tttaaaagtt tccgtcacac     1980

acaattctct tctcaggaag tatttctcat ttaggtcttc aaagtagcct gactgtgtgc     2040

atgtgtgtgt gtgataggtt atttataaag actttggata gaaggagatg tattttatta     2100

cctcctattc tagagcccca tgctcctaac aagccagaga ggccccaaac aggattgttt     2160

ctttcctcca cagcccttct gcccatctga gattgaggga gcatcgtcca cttgagatca     2220

gggatggggt ggagaatggg tcatgtcatg taatgagaaa agccctcttc gggatcatga     2280

gacttggttc tagtccaatt tctgccactg aggatgaatg taactgtggg caaactattt     2340

accctccttt atctgtgaaa tgaaagggtt gaattgatgg atctctaaag gcttttgtcc     2400

tctatgagga tgtgaaaaac tagggaccac aaaagggaac aagcaaaaaa gtttggattc     2460

gataaagtga tatgtaatag ttgcagaagg ctttatatat gcttataatg aaaagatatt     2520

ttttgtatat tgacagcata atttattttt aatgctgtca ttacacttaa agtcacagga     2580

aaaaaatata catgcttact caggctttct taaaaataaa tttttataga gatccttgag     2640

taaagacatt ttgcttaatt tcttttttct tattccccac ttgtatatcc cctaccagta     2700

ccgggatctg cacacatctt tttgcagtta cctcttcata gccatgaacc aaaacgttct     2760

atgaggagca tgcaagtaag tcaagcctcc tattctgtta gtacttatta gaggaggaga     2820

tggttttcat tgcatagtga cattttctta gccttaacgt tctgatagta gcttactact     2880

cacttctctt tttcagtttt cataataagt attcattttt ttgccataat gcttcctgta     2940

aagccaattt tatatactaa taaaacatga actgcccact cttcatgcct gccaaacttg     3000

gggcaattga tgctaaatgg tatttttaaa ataaatgttt ttattcttta ctcttgacta     3060

aacttgttta ttttcaactc caatgaagat tgtggaagag tgttttgaaa tgaagcatcg     3120

atttgtactt catagagcac cagacacaat gtctcaccca atttggagtt ccatattttt     3180

tttatgataa agaaaaatgt tgg                                             3203


<210>  996
<211>  1804
<212>  DNA
<213>  homo sapiens

<400>  996
atgctccaag tcgcgtcaca ggcagggttg ccgagccagg atttatttac atcttcacat       60

tcaaagttcg tcatcatgaa ttttgactct tggggactgg gctgaggacg gggtggtact      120

gctcctggca gggccagagg tggatggggc ttgaaaaggg ggttcaaggc agcagatcta      180

tggttcagac gccatggagt tggtgctggt cttcctctgc agcctgctgg cccccatggt      240

cctggccagt gcagctgaaa aggagaagga aatggaccct tttcattatg attaccagac      300

cctgaggatt gggggactgg tgttcgctgt ggtcctcttc tcggttggga tcctccttat      360

cctaagtcgc aggtgcaagt gcagtttcaa tcagaagccc cgggccccag gagatgagga      420

agcccaggtg gagaacctca tcaccgccaa tgcaacagag ccccagaaag cagagaactg      480

aagtgcagcc atcaggtgga agcctctgga acctgaggcg gctgcttgaa cctttggatg      540

caaatgtcga tgcttaagaa aaccggccac ttcagcaaca gccctttccc caggagaagc      600

caagaacttg tgtgtccccc accctatccc ctctaacacc attcctccac ctgatgatgc      660

aactaacact tgcctcccca ctgcagcctg cggtcctgcc cacctcccgt gatgtgtgtg      720

tgtgtgtgtg tgtgtgtgac tgtgtgtgtt tgctaactgt ggtctttgtg gctacttgtt      780

tgtggatggt attgtgtttg ttagtgaact gtggactcgc tttcccaggc aggggctgag      840

ccacatggcc atctgctcct ccctgccccc gtggccctcc atcaccttct gctcctagga      900

ggctgcttgt tgcccgagac cagccccctc ccctgattta gggatgcgta gggtaagagc      960

acgggcagtg gtcttcagtc gtcttgggac ctgggaaggt ttgcagcact ttgtcatcat     1020

tcttcatgga ctcctttcac tcctttaaca aaaaccttgc ttccttatcc cacctgatcc     1080

cagtctgaag gtctcttagc aactggagat acaaagcaag gagctggtga gcccagcgtt     1140

gacgtcaggc aggctatgcc cttccgtggt taatttcttc ccaggggctt ccacgaggag     1200

tccccatctg ccccgcccct tcacagagcg cccggggatt ccaggcccag ggcttctact     1260

ctgcccctgg ggaatgtgtc ccctgcatat cttctcagca ataactccat gggctctggg     1320

accctacccc ttccaacctt ccctgcttct gagacttcaa tctacagccc agctcatcca     1380

gatgcagact acagtccctg caattgggtc tctggcaggc aatagttgaa ggactcctgt     1440

tccgttgggg ccagcacacc gggatggatg gagggagagc agaggccttt gcttctctgc     1500

ctacgtcccc ttagatgggc agcagaggca actcccgcat cctttgctct gcctgtcagt     1560

ggtcagagcg gtgagcgagg tgggttggag actcagcagg ctccgtgcag cccttgggaa     1620

cagtgagagg ttgaaggtca taacgagagt gggaactcaa cccagatccc gcccctcctg     1680

tcctctgtgt tcccgcggaa accaaccaaa ccgtgcgctg tgacccattg ctgttctctg     1740

tatcgtgatc tatcctcaac aacaacagaa aaaaggaata aaatatcctt tgtttcctag     1800

tggc                                                                  1804


<210>  997
<211>  4311
<212>  DNA
<213>  homo sapiens

<400>  997
gtgctcgggg gttccctggc cctttcggca ggggtaaaac aataagaggg ggcggtggca       60

aagggggcgg gacgtccgtg gtccttgtcg cacgtcgcag cgcctggcgc ccgggaagag      120

gtggttgtga ggcagacgaa ctcgcggctc tccggcttcc gaggcttccg agttgtcgga      180

ggaagggggc ggcgagcaat aagaacccgc cgcacccggt cctcagcgac tcttctgacc      240

tccgcgcgac gtacccgccg ccgccgttgg ctggagcatt tgacattgtg cagcaaagaa      300

atggttatgg agaagcccag tccgctgctt gtagggcggg agtttgtgag gcaatattat      360

actttgctga ataaagctcc ggaatattta cacaggtttt atggcaggaa ttcttcctat      420

gttcatggtg gagtagatgc tagtggaaag ccccaggaag ctgtttatgg ccaaaatgat      480

atacaccaca aagtattatc tctgaacttc agtgaatgtc atactaaaat tcgtcatgtg      540

gatgctcatg caaccttgag tgatggagta gttgtccagg tcatgggttt gctgtctaac      600

agtggacaac cagaaagaaa gtttatgcaa acctttgttc tggctcctga aggatctgtt      660

ccaaataaat tttatgttca caatgatatg tttcgttatg aagatgaagt gtttggtgat      720

tctgagcctg aacttgatga agaatcagaa gatgaagtag aagaggaaca agaagaaaga      780

caaccatctc ctgaacctgt gcaagaaaat gctaacagtg gttactatga agctcaccct      840

gtgactaatg gcatagagga gcctttggaa gaatcctctc atgaacctga acctgagcca      900

gaatctgaaa caaagactga agagctgaaa ccacaagtgg aggagaagaa cttagaagaa      960

ctagaggaga aatctactac tcctcctccg gcagaacctg tttctctgcc acaagaacca     1020

ccaaagccaa gagtcgaagc taaaccagaa gttcaatctc agccacctcg tgtgcgtgaa     1080

caacgaccta gagaacgacc tggttttcct cctagaggac caagaccagg cagaggagat     1140

atggaacaga atgactctga caaccgtaga ataattcgct atccagatag tcatcaactt     1200

tttgttggta acttgccaca tgatattgat gaaaatgagc taaaggaatt cttcatgagt     1260

tttggaaacg ttgtggaact tcgcatcaat accaagggtg ttgggggaaa gcttccaaat     1320

tttggttttg tggtttttga tgactctgaa ccagttcaga gaatcttaat tgcaaaaccg     1380

attatgtttc gaggggaagt acgtttaaat gtggaagaga aaaaaacaag agctgcaaga     1440

gagcgagaaa ccagaggtgg tggtgatgat cgcagggata ttaggcgcaa tgatcgaggt     1500

cccggtggtc cacgtggaat tgtgggtggt ggaatgatgc gtgatcgtga tggaagagga     1560

cctcctccaa ggggtggcat ggcacagaaa cttggctctg gaagaggaac cgggcaaatg     1620

gagggccgct tcacaggaca gcgtcgctga agctccactg ttggcaaagt cttggcagtg     1680

gtacattatt catcgtgttt gcattcttgt taattttttt tttggctttg gaatgtgaca     1740

cagccttttt gatcatttct ttgatgtgaa aagcatcttt ggttatcagt taaattgagg     1800

tggacattat ttccccaatt tcacaacagg attcacattg ttaatttata aatctagact     1860

tggagaatta aggactgaga aatgaccata tcttaaacta tctacgacaa agtgaactta     1920

aaaggacatg cccactgaat tcaggtcctt tgagtaaaaa aaaaatcttc tgctgcacat     1980

tttgtttaag tgttactgtt tctgcctgtt aatgctggga acacaaatag tgcaatttgt     2040

gcaattggag aatcttgcct tttttcttgg ctccccccaa aaatacaaac caacagaaac     2100

ttgttatgca ctcatcaaaa tgtactaatg ggtactctga actcattaac attgacatct     2160

gcaacaggag gcaacaggga aaaaatctca tcttcttttc cagtagaaaa tagtttgtga     2220

aatgatgagg gcattttatc tgcttgctgt gaccagcgtg tgtacacata aaccttaaca     2280

agactacaag tatattccag aaggaaatca ttttagttat gaactaaata ataaaaatta     2340

gaacttcaaa tgcgatggtc ttgactatta gaccagattt agtagctcca tatctaagat     2400

ttttctacct gcccctcttc agtacaggga tggctggctg ctcaacacac tcctcctccc     2460

cttttttcct ttctttaagc tgtgtacagt gaaaattgtc tttactgtat ttttgttctc     2520

tggtaatgta ataagcatga tggtgccttc tattaataca tcattccagt cttgctggta     2580

attttgtaca gtatagtgta tgaattgctg tgctgcaaag ccaaacagct gcaaaatgtt     2640

gaaaaatcat cgaaatgtat aaaaattgca gtatctttaa aatcagtaaa atggactagc     2700

atattattta tcttgttctt cagttaacaa ctttgtgttc tctgtgggag ggagggagtc     2760

ctgtgtgttt gtggggagag ggaaggagga agtcagttat ttgagtaagc ctctagttga     2820

cttttctctt agcctgaatg tggacgttga aacatatcac ttcagggctt ggaaaagtca     2880

gtcaacttga cgtacatttt tagtgacatt ttaaaagcag tcagattcta taaatggcaa     2940

gtaagcctga agtgaggata ctgcaatttt cggagaaaag aacagcagct ctttaagtgt     3000

ttgcattttc tatttggggg gcagggaact gtcattcatt ttgcacaatt cttgaactga     3060

tgtcagcacc cgagtggctc ctgaatttaa gtctgggacg acatctttta tttttacatg     3120

aatctttaaa caattctgtg agcaaagttt gtagctgctg gattattgtc tgtctttata     3180

gcaagttcca gtaaaccaca agtatggcaa agcttatcca attttatgct tggagcagtc     3240

agtacatacc agtttctgat gtttcaggca ggagtggggt aaataagtgt gaccacttaa     3300

agctgctcgt tagcatggaa gacttctcca ttctatcttt gtaaaacaga caagatatgc     3360

acttgacata gtagcaaatt ggttctgaat tatgcaactg tttgctattt agtaaactag     3420

caaatgatgc atgtattttg tttttcatgt actgggcaat atgagtaaaa tctgtccctt     3480

tttccccctt tgaatgaggt cttccatgtt tgagggaaag tcttgcacta ttgcatatat     3540

tttggggaca cagattttca tagtttccat ttttgggggg cttaaggatt tttttttttt     3600

ctgtttgaaa cagttttata ctttctgata tagtacttga aattcttacc agaaaattac     3660

tttggagttt tgaagccttt attaatacta cttttaaaga agcagttgtt ttattgtcaa     3720

tgtttttttt cccccaagca tattttcttg tatttctgtt tccatatata tatatatata     3780

tataatttcc aattcaggat attgccctgc catccatgaa aactgttctg gcaccaaaag     3840

taatgacaaa tgttaagtgt aataatagaa aagtagagca aagagccatt cagcttcagt     3900

ctttacatac catgaataaa acattaaaac atcatatgga gaagtttaca tggtgattgt     3960

tcacctgcag tactgtggag ttttaacatt ttgtcctctt ttcagtgaaa cagagtaaaa     4020

atattcatct accattactg ttatttgctg attttgtttt attttttgat ggtaatattc     4080

tatccttatg acactattgc aaccaaattg gctttaccat cttggcttta gtaggtatag     4140

aagacaatgg attaccatct ttattgctgt aatgtgttaa gcattatatg ctagtagaat     4200

ctagtttaat tgtttcaggt ggaaagtatt ctttgagttt ccatattgaa tgtgtttgga     4260

ctaaacaaac aataaactac tgatgtctgc agcatttatc tatgtcccta a              4311


<210>  998
<211>  1394
<212>  DNA
<213>  homo sapiens

<400>  998
ttaaggaggt gcagtcttat gggagggaca ggggcggagt cagtctttaa aagctgttcc       60

caggtctggc ccgcctgcca caaacgctga gcccaggtgg gagaggtctg gcctatccgc      120

gcctggcagc tgtcggaact ccggagacca caaaggggtt tatggtttac cccctccacg      180

gaaggtcggt ctgatcgcag ctgcgggtcg gggagaggga ccgggggtcc cccagtcagt      240

aggcctcaga acacctcttc agtgccgggg caccagacag cggattttgc attcgactct      300

ccccaaagtg tgccgaacag gttggaagca aaggctccgg tttaagctct gggcttgggg      360

ataaaataca ctttttaagg acccaagttc ctcggcaacg actccagact gggaagacct      420

ttccattttc aggatcgacg cttcacgttg aggggagggc attcaggacg ccctcttaag      480

gcttctccca acccatggcg ctaccaggct cctcacagga ccaggcctgg agcctggagc      540

ctccggctgc cacggctgct gcctcctcat cttcgggacc ccaggagcgg gagggcgctg      600

ggagccccgc ggcccccggg acgctgcccc tggagaaggt gaagcggccg atgaacgcgt      660

tcatggtgtg gagctccgct cagcgccgcc agatggcgca gcagaacccc aagatgcaca      720

actccgagat ctccaagcgc ctgggcgcgc agtggaagct gctggacgag gacgagaagc      780

ggcccttcgt ggaggaggcc aagcggctcc gcgcccgaca cctgcgcgac taccccgact      840

acaagtaccg gcctcggcgc aaggccaaga gctcgggcgc cggaccttcc cgctgcggac      900

agggaagagg caacctggcc agcggcggcc cgctctgggg gccggggtac gcgaccaccc      960

aaccgagcag aggctttggg tacagacccc ccagctactc gacagcctac ctgcctggca     1020

gctatggctc ttcccactgc aaactggaag ccccctcacc gtgctccctc cctcagagtg     1080

accctaggct ccagggggaa ctgctgccca cctataccca ctacctgccc cctggctctc     1140

ccactccata caaccctccc cttgctggtg cccccatgcc cctaacccac ctctaaccct     1200

catggacgca gacctcacgg gacgggcctc atcctccttt tttaatccag cagcatcccc     1260

taccccaggc tgtcaaccct ttctcctgtt ggactacagt tcagaggcag cctgcagtcc     1320

tcccatgata gccagggaga gccgcacaac atacaattat atttttggta gtattaaaca     1380

gttttgtatt attc                                                       1394


<210>  999
<211>  1747
<212>  DNA
<213>  homo sapiens

<400>  999
actgaaggct agagaacaat tccgagaaag agacggagag agagggaaga aaaagacaga       60

tagatagata ttggggggaa ggagaaaaaa ggagaagaga gggaagagag gacagcggag      120

agagagcacc agagagagag ggagagagag agagagcgct agagagaggg agcgagcatg      180

tgcgatgagc aatagctgtg gaccttacag ttgctgctaa ctgccctggt gtgtgtgagg      240

gagagagagg gagggaggga gagagagcgc gctagcgcga gagagcgagt gagcaagcga      300

gcagaaaaga ggtggagagg gggggaataa gaaagagaga gaaggaaagg agagaaggca      360

ggaagaaggc aagggacgag acaaccatgc tgtgctgtat gagaagaacc aaacaggttg      420

aaaaaaatga tgacgaccaa aagattgaac aagatggtat caaaccagaa gataaagctc      480

ataaggccgc aaccaaaatt caggctagct tccgtggaca cataacaagg aaaaagctca      540

aaggagagaa gaaggatgat gtccaagctg ctgaggctga agctaataag aaggatgaag      600

cccctgttgc cgatggggtg gagaagaagg gagaaggcac cactactgcc gaagcagccc      660

cagccactgg ctccaagcct gatgagcccg gcaaagcagg agaaactcct tccgaggaga      720

agaaggggga gggtgatgct gccacagagc aggcagcccc ccaggctcct gcatcctcag      780

aggagaaggc cggctcagct gagacagaaa gtgccactaa agcttccact gataactcgc      840

cgtcctccaa ggctgaagat gccccagcca aggaggagcc taaacaagcc gatgtgcctg      900

ctgctgtcac tgctgctgct gccaccaccc ctgccgcaga ggatgctgct gccaaggcaa      960

cagcccagcc tccaacggag actggggaga gcagccaagc tgaagagaac atagaagctg     1020

tagatgaaac caaacctaag gaaagtgccc ggcaggacga gggtaaagaa gaggaacctg     1080

aggctgacca agaacatgcc tgaactctaa gaaatggctt tccacatccc caccctcccc     1140

tctcctgagc ctgtctctcc ctaccctctt ctcagctcca ctctgaagtc ccttcctgtc     1200

ctgctcacgt ctgtgagtct gtcctttccc acccactagc cctctttctc tctgtgtggc     1260

aaacatttaa aaaaaaaaaa aaaaagcagg aaagatccca agtcaaacag tgtggcttaa     1320

acattttttg tttcttggtg ttgttatggc aagtttttgg taatgatgat tcaatcattt     1380

tgggaaattc ttgcactgta tccaagttat ttgatctggt gcgtgtggcc ctgtgggagt     1440

ccactttcct ctctctctct ctctctgttc caagtgtgtg tgcaatgttc cgttcatctg     1500

aggagtccaa aatatcgagt gaattcaaaa tcatttttgt tttcctcctt ttcaatgtga     1560

tggaatgaac aaaaaggaaa aaattcaaaa aacccagttt gttttaaaaa taaataaata     1620

aagcaaatgt gccaattagc gtaaacttgc ggctctaagg ctcctttttc aacccgaata     1680

ttaataaatc atgagagtaa tcaaggtcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaa                                                               1747


<210>  1000
<211>  2599
<212>  DNA
<213>  homo sapiens

<400>  1000
gaaaagactc ggggttccga gggccgcaga ccgctagccc tacgtcactt ccgcttcctt       60

tcccgcaggg cgggtaattc gaacgttttt tgcagcgagt ggccttcccg gttggcgcgc      120

gcccggggcg gcggcgctgg aggagctcga gacggagcct aagttatgtc tgggaggcga      180

acgcggtccg gaggagccgc tcagcgctcc gggccaaggg ccccatctcc tactaagcct      240

ctgcggaggt cccagcggaa atcaggctct gaactcccga gcatcctccc tgaaatctgg      300

ccgaagacac ccagtgcggc tgcagtcaga aagcccatcg tcttaaagag gatcgtggcc      360

catgctgtag aggtcccagc tgtccaatca cctcgcagga gccctaggat ttcctttttc      420

ttggagaaag aaaacgagcc ccctggcagg gagcttacta aggaggacct tttcaagaca      480

cacagcgtcc ctgccacccc caccagcact cctgtgccga accctgaggc cgagtccagc      540

tccaaggaag gagagctgga cgccagagac ttggaaatgt ctaagaaagt caggcgttcc      600

tacagccggc tggagaccct gggctctgcc tctacctcca ccccaggccg ccggtcctgc      660

tttggcttcg aggggctgct gggggcagaa gacttgtccg gagtctcgcc agtggtgtgc      720

tccaaactca ccgaggtccc cagggtttgt gcaaagccct gggccccaga catgactctc      780

cctggaatct ccccaccacc cgagaaacag aaacgtaaga agaagaaaat gccagagatc      840

ttgaaaacgg agctggatga gtgggctgcg gccatgaatg ccgagtttga agctgctgag      900

cagtttgatc tcctggttga atgagatgca gtggggggtg cacctggcca gactctccct      960

cctgtcctgt acatagccac ctccctgtgg agaggacact tagggtcccc tcccctggtc     1020

ttgttacctg tgtgtgtgct ggtgctgcgc atgaggactg tctgcctttg agggcttggg     1080

cagcagcggc agccatcttg gttttaggaa atggggccgc ctggcccagc cactcactgg     1140

tgtcctgtct cttgtcgtcc tgtccttcct atctccccaa agtaccatag ccagtttcca     1200

gatgggccac agactgggga ggagaatcag tggcccagcc agaagttaaa gggctgaggg     1260

ttgaggtgag aggcacctct gctcttgttg ggaggggtgg ctgcttggaa ataggcccag     1320

gggctctgcc agcctcggcc tctccctcct gagttgcctt ctgttggtgg ctttcttctt     1380

gaacccacct gtgtaaagag gttttcagtt ccgtgggttt cccctttgat tctgtaaata     1440

gtcccagaga gaattcgtgg gctgagggca attctgtctt ggaggaagaa gctggacatt     1500

cagcctgtgg agtctgagtt ttgaaggatg tagggagcct tagttgggtc tcagaccata     1560

agtgtgtact acacagaagc tgtgttttct agttctggtc tgctgttgag atgtttggta     1620

aatgccaggt tgatagggcg ctggctgctt ggagcaaagg gtgcatttca gggtgtggcc     1680

accaggtgct gtgagtttct gtggctcatg gcctctgggc tggtcccttg cacagggccc     1740

acgctggagt cttaccactc tgctgcaggg gtggaaggtg gcccctcttg tcacccatac     1800

ccatttctta caaaataagt tacaccgagt ctacttggcc ctagaagaga aagttgaaga     1860

gtcccagacc tactagcatt ttgcaactat gcttgtaaag tcctcggaaa gtttcctcgc     1920

gtaccagaca gcggcggggg ctgatagcaa ttttagtttt tggcctccct atcctctcac     1980

atgagaacac tgcctggatg catctcatga tctctggaga atttccccat ctttctcttc     2040

tttccatcgt gtggattcaa tagtgtggat ttgaaggctg ccctgccccc gactctcctg     2100

ccgcacccct ggccattgta ccttttgatg tttagaagtt cgtggaagta gacgctgagg     2160

tgtgcagagg agctggtgga taacagagaa tgccagggaa gatgagtgct gggtcagggt     2220

acttggatga aacggtgcag gccaggcggg ccctaataaa accctctgcc aggtctggga     2280

gtcccaggcc atctgctcaa cgctctgtgg tttgtcagac ctgcaagcaa gccccctgct     2340

ggggaagcct aggtgtcctt gagctgaacc gcactgaaga actcttgtcc tcactggctg     2400

atgcagcaga actcttggga aatgtcttag tcctgcagaa tcaggagtca ccagatgatg     2460

cagagttgag atcatcattg caaagttctc tgttcctgag gaactaaatt taaggaaaaa     2520

atgggatttt gttttagagt tggaaaaaaa gcctgattaa agagtttctg cctgttaaaa     2580

aaaaaaaaaa aaaaaaaaa                                                  2599


<210>  1001
<211>  1923
<212>  DNA
<213>  homo sapiens

<400>  1001
agcgcggtga gtttgaaact gctcgcactt ggcttcaaag ctggctcttg gaaattgagc       60

ggagagcgac gcggttgttg tagctgccgc tgcggccgcc gcggaataat aagccgggat      120

ctaccatacc cattgactaa ctatggaaga ttataccaaa atagagaaaa ttggagaagg      180

tacctatgga gttgtgtata agggtagaca caaaactaca ggtcaagtgg tagccatgaa      240

aaaaatcaga ctagaaagtg aagaggaagg ggttcctagt actgcaattc gggaaatttc      300

tctattaaag gaacttcgtc atccaaatat agtcagtctt caggatgtgc ttatgcagga      360

ttccaggtta tatctcatct ttgagtttct ttccatggat ctgaagaaat acttggattc      420

tatccctcct ggtcagtaca tggattcttc acttgttaag agttatttat accaaatcct      480

acaggggatt gtgttttgtc actctagaag agttcttcac agagacttaa aacctcaaaa      540

tctcttgatt gatgacaaag gaacaattaa actggctgat tttggccttg ccagagcttt      600

tggaatacct atcagagtat atacacatga ggtagtaaca ctctggtaca gatctccaga      660

agtattgctg gggtcagctc gttactcaac tccagttgac atttggagta taggcaccat      720

atttgctgaa ctagcaacta agaaaccact tttccatggg gattcagaaa ttgatcaact      780

cttcaggatt ttcagagctt tgggcactcc caataatgaa gtgtggccag aagtggaatc      840

tttacaggac tataagaata catttcccaa atggaaacca ggaagcctag catcccatgt      900

caaaaacttg gatgaaaatg gcttggattt gctctcgaaa atgttaatct atgatccagc      960

caaacgaatt tctggcaaaa tggcactgaa tcatccatat tttaatgatt tggacaatca     1020

gattaagaag atgtagcttt ctgacaaaaa gtttccatat gttatatcaa cagatagttg     1080

tgtttttatt gttaactctt gtctattttt gtcttatata tatttctttg ttatcaaact     1140

tcagctgtac ttcgtcttct aatttcaaaa atataactta aaaatgtaaa tattctatat     1200

gaatttaaat ataattctgt aaatgtgtgt aggtctcact gtaacaacta tttgttacta     1260

taataaaact ataatattga tgtcaggaat caggaaaaaa tttgagttgg cttaaatcat     1320

ctcagtcctt atggcagttt tattttcctg tagttggaac tactaaaatt taggaaaatg     1380

ctaagttcaa gtttcgtaat gctttgaagt atttttatgc tctgaatgtt taaatgttct     1440

catcagtttc ttgccatgtt gttaactata caacctggct aaagatgaat atttttctac     1500

tggtatttta atttttgacc taaatgttta agcattcgga atgagaaaac tatacagatt     1560

tgagaaatga tgctaaattt ataggagttt tcagtaactt aaaaagctaa catgagagca     1620

tgccaaaatt tgctaagtct tacaaagatc aagggctgtc cgcaacaggg aagaacagtt     1680

ttgaaaattt atgaactatc ttatttttag gtaggttttg aaagcttttt gtctaagtga     1740

attcttatgc cttggtcaga gtaataactg aaggagttgc ttatcttggc tttcgagtct     1800

gagtttaaaa ctacacattt tgacatagtg tttattagca gccatctaaa aaggctctaa     1860

tgtatattta actaaaatta ctagctttgg gaattaaact gtttaacaaa taaaaaaaaa     1920

aaa                                                                   1923


<210>  1002
<211>  2122
<212>  DNA
<213>  homo sapiens

<400>  1002
gcgagagttg cttttgcgcg cgaactgtaa gtgccagggt ctcagggtca ggtcgcggct       60

ggtcactgtg caggcgcttg ggtgacgcga cgatctcagc ggatctggtc accttcgtct      120

ccccgccatg gagacctcag cactcaagca gcaggagcag cccgcggcga ccaagatcag      180

gaacctgccc tgggttgaaa aataccggcc acagaccctg aatgatctca tttctcatca      240

ggacattctg agtaccattc agaagtttat caatgaagac cgactgccac acttgcttct      300

ctacggtccc ccagggacag gcaagacatc taccatccta gcctgtgcga aacagctata      360

taaagacaaa gaatttggct ccatggtctt ggagctgaat gcttcagatg accgaggaat      420

agacatcatt cgaggaccga tcctgagctt tgctagcaca aggacaatat ttaagaaagg      480

ctttaagcta gtgatcttgg atgaagcaga cgccatgact caggacgccc agaatgcctt      540

gagaagagta attgagaaat tcacagaaaa taccagattc tgcctcatct gtaactatct      600

gtcaaagatc atccctgcct tgcagtcccg ctgcacgagg tttcggttcg gtcccctgac      660

tcctgaactc atggttcccc gcctggaaca tgtcgtggaa gaagagaaag ttgatataag      720

tgaagatgga atgaaagcac tagtcactct ttccagtgga gacatgcgta gggctctgaa      780

cattttgcag agcaccaata tggcctttgg gaaggtgaca gaggagactg tctacacctg      840

caccgggcac ccgctcaagt cagacattgc caacatcctg gactggatgt tgaatcaaga      900

tttcaccaca gcctacagaa atattacaga gttgaaaact ctgaaggggt tggcactgca      960

tgatatcctg acagagatac acttgtttgt gcatagagtt gactttccat cttcagttcg     1020

aatacattta ttgaccaaaa tggcagacat tgagtacagg ctttctgttg gcaccaacga     1080

gaagatccag ctgagctccc tcattgctgc atttcaagtc accagagacc tgattgttgc     1140

agaggcctag atgctctgag ggccattcac aattctcagg gctcagcagt gatgggagaa     1200

cagaggacag ttccaggata aactgctgcc tggggctgtg ggatgaatca gtcaccccga     1260

atcttggaaa aacccccttc caggagagga tgggcaggca tttaaaaagt accatttttg     1320

tggttgtttg gagcagggat gtacaaaata attttaatgt attaactcat actgcctgtc     1380

ttttataggg gaaaaaaata acctttttta ttttaaagtt ataaggtttt taccttttag     1440

ttgcttggat gacagggaat tagcctaccc cattttggtc tggaacagaa gactttcaaa     1500

tttaatatgg tccaagtgtc ttcctactca aggtaaacat tatctccaaa attacattta     1560

tgattctaat atttggcatt gtgtctgtat ctaatttaaa cagatgttaa tggacgtctg     1620

gccgaaacta ttatactttt ataagatgag ctgaatcctc ttactttaaa aactggtctt     1680

tttatttacc ctctgtggta gaagagtcac cagcaggttc caaattgatg tgtatgatag     1740

gaaaaaaacc ttaattttaa atataatata gagccttaaa ctatgccact gggtggcaga     1800

ggctgtataa aacgcacttg ttttcatgca ggagcggggc aagtaaggtt gagcctgact     1860

gtaaacctag aactgcggaa ggactgggac ttttgtacaa atttcacatt tattttacag     1920

caatcatgct gcatttgtgt tagtgttctt tataataaaa aacaaagcag cctcctggct     1980

ggctgtgtta caagtgactc ttccttagac agctagaaag atgctgactt tgtcaaactt     2040

gcatttatat gaaaaccttc tgtctctaat atcacagaat aaactttctt tagatgctgt     2100

tctttataaa aaaaaaaaaa aa                                              2122


<210>  1003
<211>  2321
<212>  DNA
<213>  homo sapiens

<400>  1003
ctcttcaatc tcagcacctc caagggtcag cacctcccct ccggctccct ccgctaccgc       60

gggccggaac ttttgtcgat aggaacgggt ttgcacagtt gagtgttgtc ggccggcgtg      120

aaggagacta gggggccatc ctcttccttt cgccgtcgcc gccgcggagc ggagtcgagc      180

cgagctgatt tgatcgagga gcgcggttac cggacgggct gggtctatgg tcgctccgcg      240

ggccgctccg ccggctggtg cttttttatc agggcaagct gtgttccatg gcagggaact      300

tttggcagag ctcccactat ttgcaatgga ttttggataa acaagatctg ttgaaggagc      360

gccaaaagga tttaaagttt ctctcagagg aagaatattg gaagttacaa atatttttta      420

caaatgttat ccaagcatta ggtgaacatc ttaaattaag acaacaagtt attgccactg      480

ctacggtata tttcaagaga ttctatgcca ggtattctct gaaaagtata gatcctgtat      540

taatggctcc tacatgtgtg tttttggcat ccaaagtaga ggaatttgga gtagtttcaa      600

atacaagatt gattgctgct gctacttctg tattaaaaac tagattttca tatgcctttc      660

caaaggaatt tccttatagg atgaatcata tattagaatg tgaattctat ctgttagaac      720

taatggattg ttgcttgata gtgtatcatc cttatagacc tttgctccag tatgtgcagg      780

acatgggcca agaagacatg ttgcttcccc ttgcatggag gatagtgaat gatacctaca      840

gaacggatct ttgcctactg tatcctcctt tcatgatagc tttagcttgc ctacatgtag      900

cctgtgttgt acagcagaaa gatgccaggc aatggtttgc tgagctttct gtggatatgg      960

aaaagatttt ggaaataatc agggttattt taaaactata tgagcagtgg aagaatttcg     1020

atgagagaaa agagatggca accattctta gtaagatgcc aaaaccaaaa ccacctccaa     1080

acagtgaagg agagcagggt ccaaatggaa gtcagaactc tagctacagc caatcttaaa     1140

acattccgaa gaattccata gtggaccact tggaaataaa ccattggaca gatttcagta     1200

atgtcttcag tggaacacaa atgaaaatga atagcttgtt tctgtcaagc atattggaaa     1260

gtgattttat ttttgcaaaa taagtttttc tttaatatga ttctagtaca taattgatta     1320

aaatctcttg attataaatg tttggaaagg ttctaagggg acctacagac agacatacat     1380

agacatttca aaattaatag cttttgatta gtataatatt tcttaatttg gataataaaa     1440

attgtagctt tttattaagc caggaaacat gaagcataat ttgtttaaaa ttctctttgg     1500

tcattgaggg accaaaaaag gacgtaaaat ttacagtcaa tctatgaggg tttttttccc     1560

tccataagtt taactttaaa actgtattta aggaatcaaa tcttacaaaa tcctggaaga     1620

ttttggtaat gatgttgata atttcaggga aattaatcaa gtacctatat tgatttaaaa     1680

gtgtatttta ttcagtagtt tgaggatctt gccatggaag atactagccc agcctagcag     1740

aaaagtgcaa tatgtatagc atactttgac attttaaaca tgatagtcca taaccatttt     1800

gaaatgctgg gcaaactaca tgaagttatt tataattaat tcacagctaa tcaggcattt     1860

tgaaagctta attggattca aaaaccataa tgttggaatt tggtaaaatt ttaatgttga     1920

tttttactgt gaaaaggttt ttataagata tacacaccct agtttaatgt tgtgtcttgg     1980

tgtggattta cagatttact acaggtattc tgaaccagga acacaatcag gtttcaggcc     2040

agtttgatac tggctgtcct taattctaat atgagagtag gacatcatac taaatgttat     2100

gtcagtggga ctgtactgtc tgtggaactt agcaaattaa tcattttctt cagacttgaa     2160

ggagagtgat aaataaaatt tggagtcata ggatattgat gcacaattta aggattaaac     2220

atttttaatc aattgtggat gatggcttat taaatgttga cttcctagta taaaactgca     2280

agaataaaag taacttctcc agctgtaaaa aaaaaaaaaa a                         2321


<210>  1004
<211>  2019
<212>  DNA
<213>  homo sapiens

<400>  1004
gaaaaggcgg aggcggcggc ccctccggct cccactgcct cccccgccgc accccctccc       60

caccttccgc acccgccaaa cttgatgtga ccctggcccg acgcggaggc tgcccctctc      120

actgccccgt gggtcccccg ccacccgctc cgcacccgcg agcgcaccgc tccccgcgcc      180

ccttcccact tcccgcgggg ccggcgccgc gctcgccctc gcgttccttc ccgccgcccc      240

ctcccccgca ccatgagcaa cctgaagccg gacggcgagc acggcggcag caccggcacc      300

ggctccggcg cgggctccgg cggcgccctg gaggaggagg tccggacact gtttgtcagc      360

ggcctccctg tggacattaa acccagagaa ctctacttgc tcttccggcc gttcaagggg      420

tatgaagggt ccctgatcaa gctcactgca agacagcctg ttggttttgt gatctttgac      480

agccgtgcag gagcagaagc ggccaagaat gcgctgaacg gtattcgctt tgatcccgaa      540

aatccacaga ctctgaggct agagtttgcc aaagccaaca ccaagatggc caagagcaag      600

ctaatggcaa ctccaaatcc cagcaacgtg caccccgccc taggagcaca cttcatcgca      660

cgggacccct atgacctgat gggggctgct ctgatccctg catccccaga ggcctgggcc      720

ccctaccctt tgtacaccac agagctgacc ccagccatct cccatgctgc gttcacctac      780

ccaactgcca ctgccgctgc cgccgccctc cacgctcagg tgcgctggta cccttcctct      840

gacaccaccc agcaaggatg gaagtaccgt cagttctgtt agtttttcag tctggtcacc      900

ggggaggtgg ttctggtaat ctgtggtggt gccgggacag gcgccccgag ttcccactgc      960

ccccgggcgg cctgcacaga gctgctgccc tccagagact gtgaatccca agcctgactc     1020

agtggactgc ttcctgttcc cctccctcct cttcctcacc ttgttctgca ccctcaagcc     1080

tttctccaat gcctcccagg aggatttggg gactttctcc ctggggcgcc cagatccagc     1140

tcggaggcct cactgggacc tggcaaggcc tgacctcccg cccaaacttg cttctgtagc     1200

tccccctcga ggaagtgagg tgtttaattt tgcatgtttt ctggcatgaa ttaagacact     1260

tatacttgta tatatgagtg tacagtttgt tctcacactg tcaccatagc gacaggtcct     1320

ggctcccagt ggttcatcct gcctgcccct ctctcctcgc cccgcccctg cacccacccc     1380

gcttcaggga ggcccaagtt ccgtggcccc acacgcttcc aggctcagct cccacctcca     1440

cccaacagat agatggggtt tgctttttca tttcacatgg ggctcctccg ctcctgcctt     1500

ctcggatggg ccaacagtcg taagaaagcc ctctctgccc gttctgttca cctctccaca     1560

gcgcaccccg cccgccgctg ctcctcattc tttccaaacc tcgaaaccaa ccaaaacgtg     1620

agaagtattt ttgtaccctg tgtaacaaaa tatttatgca tcataaagga tttttcatgt     1680

gcgtaccatt aattattaaa gcgacctcgt tcgccctgtc agataagttt aatgtttagt     1740

ttgaggcatg aagaagaaaa gggtttccat tcttcagcag tacgcctttg tgtctggcat     1800

ttgtttaaga aaatgaaatg aaggaaacac tgtgcaatgt tttttgtttt gagcatatca     1860

gtgctttact gtcagccgca gctgtgaccg tctggccatt tcagacttgg gagatgaggc     1920

ggctgttgtc attgctgatc ctgtgagaat gtgaaactgg ataatatatg aaatgcaaaa     1980

taaaacaaaa ccaaaaaaaa aaaaaaaaaa aaaaaaaaa                            2019


<210>  1005
<211>  6303
<212>  DNA
<213>  homo sapiens

<400>  1005
gtcatgcata cattagagcc tctgatgagt ttgtctttgg ggactctggg gctgtactac       60

ccagtgtcat cacaaattac caggagaaat tgcttccagc tcacaatcac atctgctttt      120

ggcaagaact aatgcaccaa gacttcaagt tctaagcctc tgttcagatt ttaattgcaa      180

ttgatcaggt ttatattatt gtacctccag agacctccta gagccagaac ccggctggct      240

tgctgtttcc tttagagcag cgcatatcat tatttggtgt tctggtggag gacttttctg      300

atggcagaaa ttagtttctc tgggttcatc aggacgggat gcttcaagat ttaagtgcaa      360

gtgtcttctt tccaccttgt tcacaacaca gaacgttagc tcaggtacct gacaatgatg      420

agcagtttgt accagactat caggctgaaa gtttggcttt tcatggcctg ccactgaaaa      480

tcaagaaaga accccacagt ccatgttcag aaatcagctc tgcctgcagt caagaacagc      540

cctttaaatt cagctatgga gaaaagtgcc tgtacaatgt cagtgcctat gatcagaagc      600

cacaagtggg aatgaggccc tccaaccccc ccacaccatc cagcacgcca gtgtccccac      660

tgcatcatgc atctccaaac tcaactcata caccgaaacc tgaccgggcc ttcccagctc      720

acctccctcc atcgcagtcc ataccagata gcagctaccc catggaccac agatttcgcc      780

gccagctttc tgaaccctgt aactcctttc ctcctttgcc gacgatgcca agggaaggac      840

gtcctatgta ccaacgccag atgtctgagc caaacatccc cttcccacca caaggcttta      900

agcaggagta ccacgaccca gtgtatgaac acaacaccat ggttggcagt gcggccagcc      960

aaagctttcc ccctcctctg atgattaaac aggaacccag agattttgca tatgactcag     1020

aagtgcctag ctgccactcc atttatatga ggcaagaagg cttcctggct catcccagca     1080

gaacagaagg ctgtatgttt gaaaagggcc ccaggcagtt ttatgatgac acctgtgttg     1140

tcccagaaaa attcgatgga gacatcaaac aagagccagg aatgtatcgg gaaggaccca     1200

cataccaacg gcgaggatca cttcagctct ggcagttttt ggtagctctt ctggatgacc     1260

cttcaaattc tcattttatt gcctggactg gtcgaggcat ggaatttaaa ctgattgagc     1320

ctgaagaggt ggcccgacgt tggggcattc agaaaaacag gccagctatg aactatgata     1380

aacttagccg ttcactccgc tattactatg agaaaggaat tatgcaaaag gtggctggag     1440

agagatatgt ctacaagttt gtgtgtgatc cagaagccct tttctccatg gcctttccag     1500

ataatcagcg tccactgctg aagacagaca tggaacgtca catcaacgag gaggacacag     1560

tgcctctttc tcactttgat gagagcatgg cctacatgcc ggaagggggc tgctgcaacc     1620

cccaccccta caacgaaggc tacgtgtatt aacacaagtg acagtcaagc agggcgtttt     1680

tgcgcttttc cttttttctg caagatacag agaattgctg aatctttgtt ttatttctgt     1740

tgtttgtatt ttatttttaa ataataatac acaaaaaggg gcttttcctg ttgcattatt     1800

ctatggtctg ccatggactg tgcactttat ttgagggtgg gtgggagtaa tctaaacatt     1860

tattctgtgt aacaggaagc taatgggtga atgggcagag ggatttgggg attacttttt     1920

acttaggctt gggatggggt cctacaagtt ttgagtatga tgaaactata tcatgtctgt     1980

ttgatttcat aacaacataa gataatgttt attttatcgg ggtatctatg gtacagttaa     2040

tttcacgttg tgtaaatatc cacttggaga ctatttgcct tgggcatttt cccctgtcat     2100

ttatgagtct ctgcaggtgt acaaaaaaac cccaatctac tgtaaatggc agtttaattg     2160

ttagaaatga ctgtttttgc accacttgta aaaaggtatt tagcgattgc atttgctgtt     2220

tgttgtttta ttttgcttta tatatgactt gcagaggata accataaaat gggtaattct     2280

ctctgaagtt gaataatcac catgactgta aatgaggggc acaattttgg actctggcgc     2340

caaactgagt cataggccag tagcattacg tgtatctggt gccaccttgc tgtttagata     2400

caaatcatac cgtcttttaa atattttgaa gcccatttca gttaaataat gacatgtcat     2460

ggtcctttgg aatcttcatt taaatgttaa atctggaatc aaaatgaagc aaaaaatatc     2520

tgtctccttt tcactttctt cagtacataa atacattatt taatcaataa gaattaactg     2580

tactaaatca tgtattatgc tgttctagtt acagcaaaca ctctttaaga aaaatatcca     2640

atacactaaa taggtactat agtaattttt agacatggta cccattgata tgcatttaaa     2700

ccttttactg ctgtgttatg ttgataacat atataaatat tagataatgc taatgcttct     2760

gctgctgtct tttctgtaat attctctttc atgctgaatt tactatgacc atttataagc     2820

agtgcagtta actacagata gcatttcagg acaaaataga tgactcaaac catttattgc     2880

ttaaaaaata gcttacgcca tgctatgcta taagcagctt ttatgcacat tgacaaatga     2940

agagtaagct tcagcttgct aaaggaaact gtggaacctt ttgtaacttt tggtgatatg     3000

gaaaattatt tacaaaccgt caaagaatat gaggaagttg ctgtatgaca tagtgctggc     3060

actgatatta tccatcatct ctttttggac acttctgtaa atgtgattgg attgtttgaa     3120

agaagattta aagtttcaaa gttttttgtt ctgtttttgc tttgcatttg gagaaaatat     3180

tgaaagcagg gtatgttgtt tcattcacct tgaaaaaacc atgagtaaat ggggatatag     3240

aatctctgaa tagctcgcta aaagattcaa gcaagggaca tgaattttgt tccatctatc     3300

aataatatcc agaagaacaa cttttttaaa gagtctatag caaaaagcaa aaaaaaaaaa     3360

aaattctaaa cacaaagtca aaataaacct attgtaaaag catttcgtga tgagcatgaa     3420

aaagattgtt taaagatgat ccccccagct acccattttc caaaactaca cagatcacag     3480

ctcatttctc taagtggagc agttatcaag aaacccaaac accaaaattg ctactcttca     3540

catttaatcc tacaaaaagt actccaattt caaaatatgt atgtaacctg cgatttcaat     3600

gattgttgtt catatacatc atgtattatt ttggcccatt ttgggcctaa aaaagaaaac     3660

tatgccttaa aaatcagaac cttttctccc cactatgctt atgtggccat ctacagcact     3720

tagaataaaa acagatgtta aaatattcag tgaaagtttt attggaaaaa ggaattgaga     3780

tatataattg agatttggtg aaattgaagg agaaaattta agtgagtctt taaaatatat     3840

tctgaatgaa aactgtattg aggattcatt tttgttcctt ttttttcttt ttctcttttc     3900

tcctttttct tctttttaat agtctagttt tagtcagtca gtgaggaaga attgggccat     3960

gctaacgtta tcacaagaga acaatggcag aaatggtatt agttatataa tatttaagga     4020

caaactatat gttttgctgt tttaacgtag tgactcactg aactaaatac ataattgacc     4080

aacattaagt gtatttccaa tacagaaggg ttgaaaatat tacattataa actcttttga     4140

aaaatgtatc taaaattttt taagttctgt tttgattcca ctttttggtt gagtttttat     4200

gtttttgttt tcaggtagat taataaatct ggcagctgat ttctgcaaga ttcttgtgtt     4260

ttgaatttct cattgaattg gctactcaaa catagaaatc atttgttaat gatgtaatgt     4320

cttctctcag cttttatctt cactgctgtt tgctgtctct tgatgatgac atgttaatac     4380

ccaatagatt aattgcaaca aacacttata ctcaaataac taagtaaaaa taatttttct     4440

tgttatgtcc atgaaaagtg cttcagaata aaaatccaca agactgacag tgcagaacat     4500

ttttctcaaa tcatgggcgg atcttggagg tctagtttcc cgtagatgct gtaaccaatt     4560

accacaactt cagtaattta cacaaattta tcttatagtt ctggaggcag aagttcaaaa     4620

gaagccttaa gagactaaaa ccaagatgtc cttaggtctg gttccttctg gaggctccag     4680

gggagattct tccagctttc acttctagag tctgctgaca ttccttggct cctggctaca     4740

tcacttcaat ctctgcttcc atggtcacat actcttctac tatagtcaaa tttccttcct     4800

gcctcttata aggatgcttg tgattacatt taggggatgc tcagataatc caggacaatc     4860

tctccatctc aagatcctta acttaatgac gtgtgccaag tccctttggc tagataatta     4920

ttcataggtc ccagggatta ggacatggat gtaaggggtg agggcagggc tgttattcag     4980

aacaccgcac ggaggaggaa gactgtgtag caaagactct aattgattta ctcaggaaca     5040

gtggagttct gctgagggat ctaggatttg aaagtactag agtttgcttt tatttaccac     5100

tgagatattt tccccttatt ctgcataaat aattttgaaa actttctata ttaaatttca     5160

actattccac taaaatgtct ggtaatcaca tcaagccttt agattattca aatccttccc     5220

cagcccccag gaaaacacta agtcatgaaa cagaaaaaca gaaggtatga taataatagt     5280

aataacagtt aaatcagtgg tctaatccag attttatttt ttaatacatt tcttttggtg     5340

ttaatatggg ttactatgtg atcttatcat ttgctagtga ttattactta ttaggtaaga     5400

acaatgtgta aaatatgtct attactcaaa agaacaattg caaaatgagt caacttatct     5460

ttatataacc aggaaagaaa tatattgcca gaagctacag aattttgcca gatgataggg     5520

atttctaaaa tgagccactt tgtctatcat gcagcctttt cagagcttgt aatgagaaaa     5580

cattacagag gagaaggtca tttggatgtt tgttacttgg aatcctagaa aacaaaaact     5640

aaaatttaaa aataagaagt gagtaagcta ttttccattt gcgatttggt atggagaaga     5700

gaggaaatag aattattaaa aaaatacaaa ttgggtaaaa gtgatggtgg aaaaaatata     5760

aagaaggcaa atgtacatat taagcaattc tactaagaat tggaaaaatc aagtttcaaa     5820

aagatggtaa tagttgggca tgatactaga aaatttcacc cagtttattc agagctcaac     5880

tagtactttt aggacttctt tttttatata catgagactc actttgacat acttaaaaaa     5940

aaaacagttt atggaaagta cagtttaaga ggagaatttg attagactaa gtggatatct     6000

ttatagaaat attaatgatt tcagaatttt cagttacaag tgtatatacc gtggctattg     6060

tttatggatt catatgtaag gtagggtctt ttttgcatat agactccagt attagttact     6120

ttcattctaa aattatattt atgcttctat ggggaagaaa atttttaatt cacttggttg     6180

tattaaaatt atacttacgg tttgagaaaa catgctatga aaatcatgat tatagcaaat     6240

taaatatgct caaaatttaa atctaaaata aaagcccaga aactgaaaaa aaaaaaaaaa     6300

aaa                                                                   6303


<210>  1006
<211>  6249
<212>  DNA
<213>  homo sapiens

<400>  1006
gtcatgcata cattagagcc tctgatgagt ttgtctttgg ggactctggg gctgtactac       60

ccagtgtcat cacaaattac caggagaaat tgcttccagc tcacaatcac atctgctttt      120

ggcaagaact aatgcaccaa gacttcaagt tctaagcctc tgttcagatt ttaattgcaa      180

ttgatcaggt ttatattatt gtacctccag agacctccta gagccagaac ccggctggct      240

tgctgtttcc tttagagcag cgcatatcat tatttggtgt tctggtggag gacttttctg      300

atggcagaaa ttagtttctc tgggttcatc aggacgggat gcttcaagat ttaagtgcaa      360

gtgtcttctt tccaccttgt tcacaacaca gaacgttagt ggcttttcat ggcctgccac      420

tgaaaatcaa gaaagaaccc cacagtccat gttcagaaat cagctctgcc tgcagtcaag      480

aacagccctt taaattcagc tatggagaaa agtgcctgta caatgtcagt gcctatgatc      540

agaagccaca agtgggaatg aggccctcca acccccccac accatccagc acgccagtgt      600

ccccactgca tcatgcatct ccaaactcaa ctcatacacc gaaacctgac cgggccttcc      660

cagctcacct ccctccatcg cagtccatac cagatagcag ctaccccatg gaccacagat      720

ttcgccgcca gctttctgaa ccctgtaact cctttcctcc tttgccgacg atgccaaggg      780

aaggacgtcc tatgtaccaa cgccagatgt ctgagccaaa catccccttc ccaccacaag      840

gctttaagca ggagtaccac gacccagtgt atgaacacaa caccatggtt ggcagtgcgg      900

ccagccaaag ctttccccct cctctgatga ttaaacagga acccagagat tttgcatatg      960

actcagaagt gcctagctgc cactccattt atatgaggca agaaggcttc ctggctcatc     1020

ccagcagaac agaaggctgt atgtttgaaa agggccccag gcagttttat gatgacacct     1080

gtgttgtccc agaaaaattc gatggagaca tcaaacaaga gccaggaatg tatcgggaag     1140

gacccacata ccaacggcga ggatcacttc agctctggca gtttttggta gctcttctgg     1200

atgacccttc aaattctcat tttattgcct ggactggtcg aggcatggaa tttaaactga     1260

ttgagcctga agaggtggcc cgacgttggg gcattcagaa aaacaggcca gctatgaact     1320

atgataaact tagccgttca ctccgctatt actatgagaa aggaattatg caaaaggtgg     1380

ctggagagag atatgtctac aagtttgtgt gtgatccaga agcccttttc tccatggcct     1440

ttccagataa tcagcgtcca ctgctgaaga cagacatgga acgtcacatc aacgaggagg     1500

acacagtgcc tctttctcac tttgatgaga gcatggccta catgccggaa gggggctgct     1560

gcaaccccca cccctacaac gaaggctacg tgtattaaca caagtgacag tcaagcaggg     1620

cgtttttgcg cttttccttt tttctgcaag atacagagaa ttgctgaatc tttgttttat     1680

ttctgttgtt tgtattttat ttttaaataa taatacacaa aaaggggctt ttcctgttgc     1740

attattctat ggtctgccat ggactgtgca ctttatttga gggtgggtgg gagtaatcta     1800

aacatttatt ctgtgtaaca ggaagctaat gggtgaatgg gcagagggat ttggggatta     1860

ctttttactt aggcttggga tggggtccta caagttttga gtatgatgaa actatatcat     1920

gtctgtttga tttcataaca acataagata atgtttattt tatcggggta tctatggtac     1980

agttaatttc acgttgtgta aatatccact tggagactat ttgccttggg cattttcccc     2040

tgtcatttat gagtctctgc aggtgtacaa aaaaacccca atctactgta aatggcagtt     2100

taattgttag aaatgactgt ttttgcacca cttgtaaaaa ggtatttagc gattgcattt     2160

gctgtttgtt gttttatttt gctttatata tgacttgcag aggataacca taaaatgggt     2220

aattctctct gaagttgaat aatcaccatg actgtaaatg aggggcacaa ttttggactc     2280

tggcgccaaa ctgagtcata ggccagtagc attacgtgta tctggtgcca ccttgctgtt     2340

tagatacaaa tcataccgtc ttttaaatat tttgaagccc atttcagtta aataatgaca     2400

tgtcatggtc ctttggaatc ttcatttaaa tgttaaatct ggaatcaaaa tgaagcaaaa     2460

aatatctgtc tccttttcac tttcttcagt acataaatac attatttaat caataagaat     2520

taactgtact aaatcatgta ttatgctgtt ctagttacag caaacactct ttaagaaaaa     2580

tatccaatac actaaatagg tactatagta atttttagac atggtaccca ttgatatgca     2640

tttaaacctt ttactgctgt gttatgttga taacatatat aaatattaga taatgctaat     2700

gcttctgctg ctgtcttttc tgtaatattc tctttcatgc tgaatttact atgaccattt     2760

ataagcagtg cagttaacta cagatagcat ttcaggacaa aatagatgac tcaaaccatt     2820

tattgcttaa aaaatagctt acgccatgct atgctataag cagcttttat gcacattgac     2880

aaatgaagag taagcttcag cttgctaaag gaaactgtgg aaccttttgt aacttttggt     2940

gatatggaaa attatttaca aaccgtcaaa gaatatgagg aagttgctgt atgacatagt     3000

gctggcactg atattatcca tcatctcttt ttggacactt ctgtaaatgt gattggattg     3060

tttgaaagaa gatttaaagt ttcaaagttt tttgttctgt ttttgctttg catttggaga     3120

aaatattgaa agcagggtat gttgtttcat tcaccttgaa aaaaccatga gtaaatgggg     3180

atatagaatc tctgaatagc tcgctaaaag attcaagcaa gggacatgaa ttttgttcca     3240

tctatcaata atatccagaa gaacaacttt tttaaagagt ctatagcaaa aagcaaaaaa     3300

aaaaaaaaat tctaaacaca aagtcaaaat aaacctattg taaaagcatt tcgtgatgag     3360

catgaaaaag attgtttaaa gatgatcccc ccagctaccc attttccaaa actacacaga     3420

tcacagctca tttctctaag tggagcagtt atcaagaaac ccaaacacca aaattgctac     3480

tcttcacatt taatcctaca aaaagtactc caatttcaaa atatgtatgt aacctgcgat     3540

ttcaatgatt gttgttcata tacatcatgt attattttgg cccattttgg gcctaaaaaa     3600

gaaaactatg ccttaaaaat cagaaccttt tctccccact atgcttatgt ggccatctac     3660

agcacttaga ataaaaacag atgttaaaat attcagtgaa agttttattg gaaaaaggaa     3720

ttgagatata taattgagat ttggtgaaat tgaaggagaa aatttaagtg agtctttaaa     3780

atatattctg aatgaaaact gtattgagga ttcatttttg ttcctttttt ttctttttct     3840

cttttctcct ttttcttctt tttaatagtc tagttttagt cagtcagtga ggaagaattg     3900

ggccatgcta acgttatcac aagagaacaa tggcagaaat ggtattagtt atataatatt     3960

taaggacaaa ctatatgttt tgctgtttta acgtagtgac tcactgaact aaatacataa     4020

ttgaccaaca ttaagtgtat ttccaataca gaagggttga aaatattaca ttataaactc     4080

ttttgaaaaa tgtatctaaa attttttaag ttctgttttg attccacttt ttggttgagt     4140

ttttatgttt ttgttttcag gtagattaat aaatctggca gctgatttct gcaagattct     4200

tgtgttttga atttctcatt gaattggcta ctcaaacata gaaatcattt gttaatgatg     4260

taatgtcttc tctcagcttt tatcttcact gctgtttgct gtctcttgat gatgacatgt     4320

taatacccaa tagattaatt gcaacaaaca cttatactca aataactaag taaaaataat     4380

ttttcttgtt atgtccatga aaagtgcttc agaataaaaa tccacaagac tgacagtgca     4440

gaacattttt ctcaaatcat gggcggatct tggaggtcta gtttcccgta gatgctgtaa     4500

ccaattacca caacttcagt aatttacaca aatttatctt atagttctgg aggcagaagt     4560

tcaaaagaag ccttaagaga ctaaaaccaa gatgtcctta ggtctggttc cttctggagg     4620

ctccagggga gattcttcca gctttcactt ctagagtctg ctgacattcc ttggctcctg     4680

gctacatcac ttcaatctct gcttccatgg tcacatactc ttctactata gtcaaatttc     4740

cttcctgcct cttataagga tgcttgtgat tacatttagg ggatgctcag ataatccagg     4800

acaatctctc catctcaaga tccttaactt aatgacgtgt gccaagtccc tttggctaga     4860

taattattca taggtcccag ggattaggac atggatgtaa ggggtgaggg cagggctgtt     4920

attcagaaca ccgcacggag gaggaagact gtgtagcaaa gactctaatt gatttactca     4980

ggaacagtgg agttctgctg agggatctag gatttgaaag tactagagtt tgcttttatt     5040

taccactgag atattttccc cttattctgc ataaataatt ttgaaaactt tctatattaa     5100

atttcaacta ttccactaaa atgtctggta atcacatcaa gcctttagat tattcaaatc     5160

cttccccagc ccccaggaaa acactaagtc atgaaacaga aaaacagaag gtatgataat     5220

aatagtaata acagttaaat cagtggtcta atccagattt tattttttaa tacatttctt     5280

ttggtgttaa tatgggttac tatgtgatct tatcatttgc tagtgattat tacttattag     5340

gtaagaacaa tgtgtaaaat atgtctatta ctcaaaagaa caattgcaaa atgagtcaac     5400

ttatctttat ataaccagga aagaaatata ttgccagaag ctacagaatt ttgccagatg     5460

atagggattt ctaaaatgag ccactttgtc tatcatgcag ccttttcaga gcttgtaatg     5520

agaaaacatt acagaggaga aggtcatttg gatgtttgtt acttggaatc ctagaaaaca     5580

aaaactaaaa tttaaaaata agaagtgagt aagctatttt ccatttgcga tttggtatgg     5640

agaagagagg aaatagaatt attaaaaaaa tacaaattgg gtaaaagtga tggtggaaaa     5700

aatataaaga aggcaaatgt acatattaag caattctact aagaattgga aaaatcaagt     5760

ttcaaaaaga tggtaatagt tgggcatgat actagaaaat ttcacccagt ttattcagag     5820

ctcaactagt acttttagga cttctttttt tatatacatg agactcactt tgacatactt     5880

aaaaaaaaaa cagtttatgg aaagtacagt ttaagaggag aatttgatta gactaagtgg     5940

atatctttat agaaatatta atgatttcag aattttcagt tacaagtgta tataccgtgg     6000

ctattgttta tggattcata tgtaaggtag ggtctttttt gcatatagac tccagtatta     6060

gttactttca ttctaaaatt atatttatgc ttctatgggg aagaaaattt ttaattcact     6120

tggttgtatt aaaattatac ttacggtttg agaaaacatg ctatgaaaat catgattata     6180

gcaaattaaa tatgctcaaa atttaaatct aaaataaaag cccagaaact gaaaaaaaaa     6240

aaaaaaaaa                                                             6249


<210>  1007
<211>  3129
<212>  DNA
<213>  homo sapiens

<400>  1007
gaagtgaccc ggtgatgggt gggaaacaga ggtccagagc aaaggccttt gcccaaggtc       60

aggagaagga tgctgggacc tggagtcagg tgtgttcctt attccctacg tcctgatcgc      120

cctggttgga ggaatcccca ttttcttctt agagatctcg ctgggccagt tcatgaaggc      180

cggcagcatc aatgtctgga acatctgtcc cctgttcaaa ggcctgggct acgcctccat      240

ggtgatcgtc ttctactgca acacctacta catcatggtg ctggcctggg gcttctatta      300

cctggtcaag tcctttacca ccacgctgcc ctgggccaca tgtggccaca cctggaacac      360

tcccgactgc gtggagatct tccgccatga agactgtgcc aatgccagcc tggccaacct      420

cacctgtgac cagcttgctg accgccggtc ccctgtcatc gagttctggg agaacaaagt      480

cttgaggctg tctgggggac tggaggtgcc aggggccctc aactgggagg tgaccctttg      540

tctgctggcc tgctgggtgc tggtctactt ctgtgtctgg aagggggtca aatccacggg      600

aaagatcgtg tacttcactg ctacattccc ctacgtggtc ctggtcgtgc tgctggtgcg      660

tggagtgctg ctgcctggcg ccctggatgg catcatttac tatctcaagc ctgactggtc      720

aaagctgggg tcccctcagg tgtggataga tgcggggacc cagattttct tttcttacgc      780

cattggcctg ggggccctca cagccctggg cagctacaac cgcttcaaca acaactgcta      840

caaggacgcc atcatcctgg ctctcatcaa cagtgggacc agcttctttg ctggcttcgt      900

ggtcttctcc atcctgggct tcatggctgc agagcagggc gtgcacatct ccaaggtggc      960

agagtcaggg ccgggcctgg ccttcatcgc ctacccgcgg gctgtcacgc tgatgccagt     1020

ggccccactc tgggctgccc tgttcttctt catgctgttg ctgcttggtc tcgacagcca     1080

gtttgtaggt gtggagggct tcatcaccgg cctcctcgac ctcctcccgg cctcctacta     1140

cttccgtttc caaagggaga tctctgtggc cctctgttgt gccctctgct ttgtcatcga     1200

tctctccatg gtgactgatg gcgggatgta cgtcttccag ctgtttgact actactcggc     1260

cagcggcacc accctgctct ggcaggcctt ttgggagtgc gtggtggtgg cctgggtgta     1320

cggagctgac cgcttcatgg acgacattgc ctgtatgatc gggtaccgac cttgcccctg     1380

gatgaaatgg tgctggtcct tcttcacccc gctggtctgc atgggcatct tcatcttcaa     1440

cgttgtgtac tacgagccgc tggtctacaa caacacctac gtgtacccgt ggtggggtga     1500

ggccatgggc tgggccttcg ccctgtcctc catgctgtgc gtgccgctgc acctcctggg     1560

ctgcctcctc agggccaagg gcaccatggc tgagcgctgg cagcacctga cccagcccat     1620

ctggggcctc caccacttgg agtaccgagc tcaggacgca gatgtcaggg gcctgaccac     1680

cctgacccca gtgtccgaga gcagcaaggt cgtcgtggtg gagagtgtca tgtgacaact     1740

cagctcacat caccagctca cctctggtag ccatagcagc ccctgcttca gccccaccgc     1800

acccctccag ggggcctgcc tttccctgac acttttgggg tctgcctggg ggaggagggg     1860

agaaagcacc atgagtgctc actaaaacaa ctttttccat ttttaataaa acgccaaaaa     1920

tatcacaacc caccaaaaat agatgcctct ccccctccag ccctagccga gctggtccta     1980

ggccccgcct agtgccccac ccccacccac agtgctgcac tcctcctgcc cctgccacgc     2040

ccaccccctg cccacctctc caggctctgc tctgcagcac acccgtgggt gacccctcac     2100

cccagaagca gcagtggcag cttgggaaat gtgaggaagg gaaggaggga gagacgggag     2160

ggaggagaga gaggagaagg gaggcagggg aggggcagca gaaccaaggc aaatatttca     2220

gctgggctat acccctctcc ccatccctgt tatagaagct tagagagcca gccagcaatg     2280

gaaccttctg gttcctgcgc caatcgccac cagtatcaat tgtgtgagct tgggtgcgag     2340

tgcacgcgtg cgtgagtacg gagagtatat atagatctct atctcttagc aaaggtgaat     2400

gccagatgta aatggcgcct ctgggcaaag gaggcttgta ttttgcacat tttataaaaa     2460

cttgagagaa tgagatttct gcttgtatat ttctaaaaag aggaaggagc ccaaaccatc     2520

ctctccttac cactcccatc cctgtgagcc ctaccttacc cctctgcccc tagccaagga     2580

gtgtgaattt atagatctaa ctttcatagg caaaacaaaa gcttcgagct gttgcgtgtg     2640

tgagtctgtt gtgtggatgt gcgtgtgtgg tccccagccc cagactggat tggaaaagtg     2700

catggtgggg gcctcggggc tgtccccacg ctgtcccttt gccacaagtc tgtggggcaa     2760

gaggctgcaa tattccgtcc tgggtgtctg ggctgctaac ctggcctgct caggcttccc     2820

accctgtgcg gggcacaccc ccaggaaggg accctggaca cggctcccac gtccaggctt     2880

aaggtggatg cacttcccgc acctccagtc ttctgtgtag cagctttaac ccacgtttgt     2940

ctgtcacgtc cagtcccgag acggctgagt gaccccaaga aaggcttccc cgacacccag     3000

acagaggctg cagggctggg gctgggtgag ggtggcgggc ctgcggggac attctactgt     3060

gctaaaaagc cactgcagac atagcaataa aaacatgtca ttttccaaag caggaaaaaa     3120

aaaaaaaaa                                                             3129


<210>  1008
<211>  4835
<212>  DNA
<213>  homo sapiens

<400>  1008
ccttgccaag taacagcttt gctgtccaac atcgtgtgct gcttcgcgag aaagtcacat       60

tcggaccctt tggctagatt atcttagacg aattttacaa tgtgaagttc tgcatagatg      120

ccagtcaacc agatgttgga agctggctca agtacattag attcgctggc tgttatgatc      180

agcacaacct tgttgcatgc cagataaatg atcagatatt ctatagagta gttgcagaca      240

ttgcgccggg agaggagctt ctgctgttca tgaagagcga agactatccc catgaaacta      300

tggcgccgga tatccacgaa gaacggcaat atcgctgcga agactgtgac cagctctttg      360

aatctaaggc tgaactagca gatcaccaaa agtttccatg cagtactcct cactcagcat      420

tttcaatggt tgaagaggac tttcagcaaa aactcgaaag cgagaatgat ctccaagaga      480

tacacacgat ccaggagtgt aaggaatgtg accaagtttt tcctgatttg caaagcctgg      540

agaaacacat gctgtcacat actgaagaga gggaatacaa gtgtgatcag tgtcccaagg      600

catttaactg gaagtccaat ttaattcgcc accagatgtc acatgacagt ggaaagcact      660

atgaatgtga aaactgtgcc aaggttttca cggaccctag caaccttcag cggcacattc      720

gctctcagca tgtcggtgcc cgggcccatg catgcccgga gtgtggcaaa acgtttgcca      780

cttcgtcggg cctcaaacaa cacaagcaca tccacagcag tgtgaagccc tttatctgtg      840

aggtctgcca taaatcctat actcagtttt caaacctttg ccgtcataag cgcatgcatg      900

ctgattgcag aacccaaatc aagtgcaaag actgtggaca aatgttcagc actacgtctt      960

ccttaaataa acacaggagg ttttgtgagg gcaagaacca ttttgcggca ggtggatttt     1020

ttggccaagg catttcactt cctggaaccc cagctatgga taaaacgtcc atggttaata     1080

tgagtcatgc caacccgggc cttgctgact attttggcgc caataggcat cctgctggtc     1140

ttacctttcc aacagctcct ggattttctt ttagcttccc tggtctgttt ccttccggct     1200

tgtaccacag gcctcctttg atacctgcta gttctcctgt taaaggacta tcaagtactg     1260

aacagacaaa caaaagtcaa agtcccctca tgacacatcc tcagatactg ccagctacac     1320

aggatatttt gaaggcacta tctaaacacc catctgtagg ggacaataag ccagtggagc     1380

tccagcccga gaggtcctct gaagagaggc cctttgagaa aatcagtgac cagtcagaga     1440

gtagtgacct tgatgatgtc agtacaccaa gtggcagtga cctggaaaca acctcgggct     1500

ctgatctgga aagtgacatt gaaagtgata aagagaaatt taaagaaaat ggtaaaatgt     1560

tcaaagacaa agtaagccct cttcagaatc tggcttcaat aaataataag aaagaataca     1620

gcaatcattc cattttctca ccatctttag aggagcagac tgcggtgtca ggagctgtga     1680

atgattctat aaaggctatt gcttctattg ctgaaaaata ctttggttca acaggactgg     1740

tggggctgca agacaaaaaa gttggagctt taccttaccc ttccatgttt cccctcccat     1800

tttttccagc attctctcaa tcaatgtacc catttcctga tagagacttg agatcgttac     1860

ctttgaaaat ggaaccccaa tcaccaggtg aagtaaagaa actgcagaag ggcagctctg     1920

agtccccctt tgatctcacc actaagcgaa aggatgagaa gcccttgact ccagtcccct     1980

ccaagcctcc agtgacacct gccacaagcc aagaccagcc cctggatcta agtatgggca     2040

gtaggagtag agccagtggg acaaagctga ctgagcctcg aaaaaaccac gtgtttgggg     2100

gaaaaaaagg aagcaacgtc gaatcaagac ctgcttcaga tggttccttg cagcatgcaa     2160

gacccactcc tttctttatg gaccctattt acagagtaga gaaaagaaaa ctaactgacc     2220

cacttgaagc tttaaaagag aaatacttga ggccttctcc aggattcttg tttcacccac     2280

aattccaact gcctgatcag agaacttgga tgtcagctat tgaaaacatg gcagaaaagc     2340

tagagagctt cagtgccctg aaacctgagg ccagtgagct cttacagtca gtgccctcta     2400

tgttcaactt cagggcgcct cccaatgccc tgccagagaa ccttctgcgg aagggaaagg     2460

agcgctatac ctgcagatac tgtggcaaga tttttccaag gtctgcaaac ctaacacggc     2520

acttgagaac ccacacagga gagcagcctt acagatgcaa atactgtgac agatcattta     2580

gcatatcttc taacttgcaa aggcatgttc gcaacatcca caataaagag aagccattta     2640

agtgtcactt atgtgatagg tgttttggtc aacaaaccaa tttagacaga cacctaaaga     2700

aacatgagaa tgggaacatg tccggtacag caacatcgtc gcctcattct gaactggaaa     2760

gtacaggtgc gattctggat gacaaagaag atgcttactt cacagaaatt cgaaatttca     2820

ttgggaacag caaccatggc agccaatctc ccaggaatgt ggaggagaga atgaatggca     2880

gtcattttaa agatgaaaag gctttggtga ccagtcaaaa ttcagacttg ctggatgatg     2940

aagaagttga agatgaggtg ttgttagatg aggaggatga agacaatgat attactggaa     3000

aaacaggaaa ggaaccagtg acaagtaatt tacatgaagg aaaccctgag gatgactatg     3060

aagaaaccag tgccctggag atgagttgca agacatcccc agtgaggtat aaagaggaag     3120

aatataaaag tggactttct gctctagatc atataaggca cttcacagat agcctcaaaa     3180

tgaggaaaat ggaagataat caatattctg aagctgagct gtcttctttt agtacttccc     3240

atgtgccaga ggaacttaag cagccgttac acagaaagtc caaatcgcag gcatatgcta     3300

tgatgctgtc actgtctgac aaggagtccc tccattctac atcccacagt tcttccaacg     3360

tgtggcacag tatggccagg gctgcggcgg aatccagtgc tatccagtcc ataagccacg     3420

tatgacgtta tcaaggttga ccagagtggg accaagtcca acagtagcat ggctctttca     3480

tataggacta tttacaagac tgctgagcag aatgccttat aaacctgcag ggtcactcat     3540

ctaaagtcta gtgaccttaa actgaatgat ttaaaaaaga aaagaaagaa aaaagaaact     3600

atttattctc gatattttgt tttgcacagc aaaggcagct gctgacttct ggaagatcaa     3660

tcaatgcgac ttaaagtgat tcagtgaaaa caaaaaactt ggtgggctga aggcatcttc     3720

cagtttaccc caccttaggg tatgggtggg tgagaagggc agttgagatg gcagcattga     3780

tatgaatgaa cactccatag aaactgaatt ctcttttgta caagatcacc tgacatgatt     3840

gggaacagtt gcttttaatt acagatttaa tttttttctt cgttaaagtt ttatgtaatt     3900

taaccctttg aagacagaag tagttggatg aaatgcacag tcaattatta tagaaactga     3960

taacagggag tacttgttcc cccttttgcc ttcttaagta cattgtttaa aactagggaa     4020

aaagggtatg tgtatattgt aaactatgga tgttaacact caaagaggtt aagtcagtga     4080

agtaacctat tcatcaccag taccgctgta ccactaataa attgtttgcc aaatccttgt     4140

aataacatct taattttaga caatcatgtc actgttttta atgtttattt ttttgtgtgt     4200

gttgcgtgta tcatgtattt atttgttggc aaactattgt ttgttgatta aaatagcact     4260

gttccagtca gccactactt tatgacgtct gaggcacacc cctttccgaa tttcaaggac     4320

caaggtgacc cgacctgtgt atgagagtgc caaatggtgt ttggcttttc ttaacattcc     4380

tttttgtttg tttgttttgt tttccttctt aatgaactaa atacgaatag atgcaactta     4440

gtttttgtaa tactgaaatc gattcaattg tataaacgat tataatttct ttcatggaag     4500

catgattctt ctgattaaaa actgtactcc atattttatg ctggttgtct gcaagcttgt     4560

gcgatgttat gttcatgtta atcctatttg taaaatgaag tgttcccaac cttatgttaa     4620

aagagagaag taaataacag actgtattca gttattttgc cctttattga ggaaccagat     4680

ttgttttctt tttgtttgta atctcatttt gaaataatca gcaagttgag gtactttctt     4740

caaatgcttt gtacaatata aactgttatg cctttcagtg cattactatg ggaggagcaa     4800

ctaaaaaata aagacttaca aaaaggagta ttttt                                4835


<210>  1009
<211>  4891
<212>  DNA
<213>  homo sapiens

<400>  1009
agccttcttt cctcctcgcc cgcagtctcg cggagccctg ctgcttatct acgttgctaa       60

gccgggcgat ttccttgttc ctcctgcgaa acggtgcggt ctggacacgt ctccggggtg      120

ggtcgtccgg ccttcgatct tagacgaatt ttacaatgtg aagttctgca tagatgccag      180

tcaaccagat gttggaagct ggctcaagta cattagattc gctggctgtt atgatcagca      240

caaccttgtt gcatgccaga taaatgatca gatattctat agagtagttg cagacattgc      300

gccgggagag gagcttctgc tgttcatgaa gagcgaagac tatccccatg aaactatggc      360

gccggatatc cacgaagaac ggcaatatcg ctgcgaagac tgtgaccagc tctttgaatc      420

taaggctgaa ctagcagatc accaaaagtt tccatgcagt actcctcact cagcattttc      480

aatggttgaa gaggactttc agcaaaaact cgaaagcgag aatgatctcc aagagataca      540

cacgatccag gagtgtaagg aatgtgacca agtttttcct gatttgcaaa gcctggagaa      600

acacatgctg tcacatactg aagagaggga atacaagtgt gatcagtgtc ccaaggcatt      660

taactggaag tccaatttaa ttcgccacca gatgtcacat gacagtggaa agcactatga      720

atgtgaaaac tgtgccaagg ttttcacgga ccctagcaac cttcagcggc acattcgctc      780

tcagcatgtc ggtgcccggg cccatgcatg cccggagtgt ggcaaaacgt ttgccacttc      840

gtcgggcctc aaacaacaca agcacatcca cagcagtgtg aagcccttta tctgtgaggt      900

ctgccataaa tcctatactc agttttcaaa cctttgccgt cataagcgca tgcatgctga      960

ttgcagaacc caaatcaagt gcaaagactg tggacaaatg ttcagcacta cgtcttcctt     1020

aaataaacac aggaggtttt gtgagggcaa gaaccatttt gcggcaggtg gattttttgg     1080

ccaaggcatt tcacttcctg gaaccccagc tatggataaa acgtccatgg ttaatatgag     1140

tcatgccaac ccgggccttg ctgactattt tggcgccaat aggcatcctg ctggtcttac     1200

ctttccaaca gctcctggat tttcttttag cttccctggt ctgtttcctt ccggcttgta     1260

ccacaggcct cctttgatac ctgctagttc tcctgttaaa ggactatcaa gtactgaaca     1320

gacaaacaaa agtcaaagtc ccctcatgac acatcctcag atactgccag ctacacagga     1380

tattttgaag gcactatcta aacacccatc tgtaggggac aataagccag tggagctcca     1440

gcccgagagg tcctctgaag agaggccctt tgagaaaatc agtgaccagt cagagagtag     1500

tgaccttgat gatgtcagta caccaagtgg cagtgacctg gaaacaacct cgggctctga     1560

tctggaaagt gacattgaaa gtgataaaga gaaatttaaa gaaaatggta aaatgttcaa     1620

agacaaagta agccctcttc agaatctggc ttcaataaat aataagaaag aatacagcaa     1680

tcattccatt ttctcaccat ctttagagga gcagactgcg gtgtcaggag ctgtgaatga     1740

ttctataaag gctattgctt ctattgctga aaaatacttt ggttcaacag gactggtggg     1800

gctgcaagac aaaaaagttg gagctttacc ttacccttcc atgtttcccc tcccattttt     1860

tccagcattc tctcaatcaa tgtacccatt tcctgataga gacttgagat cgttaccttt     1920

gaaaatggaa ccccaatcac caggtgaagt aaagaaactg cagaagggca gctctgagtc     1980

cccctttgat ctcaccacta agcgaaagga tgagaagccc ttgactccag tcccctccaa     2040

gcctccagtg acacctgcca caagccaaga ccagcccctg gatctaagta tgggcagtag     2100

gagtagagcc agtgggacaa agctgactga gcctcgaaaa aaccacgtgt ttgggggaaa     2160

aaaaggaagc aacgtcgaat caagacctgc ttcagatggt tccttgcagc atgcaagacc     2220

cactcctttc tttatggacc ctatttacag agtagagaaa agaaaactaa ctgacccact     2280

tgaagcttta aaagagaaat acttgaggcc ttctccagga ttcttgtttc acccacaatt     2340

ccaactgcct gatcagagaa cttggatgtc agctattgaa aacatggcag aaaagctaga     2400

gagcttcagt gccctgaaac ctgaggccag tgagctctta cagtcagtgc cctctatgtt     2460

caacttcagg gcgcctccca atgccctgcc agagaacctt ctgcggaagg gaaaggagcg     2520

ctatacctgc agatactgtg gcaagatttt tccaaggtct gcaaacctaa cacggcactt     2580

gagaacccac acaggagagc agccttacag atgcaaatac tgtgacagat catttagcat     2640

atcttctaac ttgcaaaggc atgttcgcaa catccacaat aaagagaagc catttaagtg     2700

tcacttatgt gataggtgtt ttggtcaaca aaccaattta gacagacacc taaagaaaca     2760

tgagaatggg aacatgtccg gtacagcaac atcgtcgcct cattctgaac tggaaagtac     2820

aggtgcgatt ctggatgaca aagaagatgc ttacttcaca gaaattcgaa atttcattgg     2880

gaacagcaac catggcagcc aatctcccag gaatgtggag gagagaatga atggcagtca     2940

ttttaaagat gaaaaggctt tggtgaccag tcaaaattca gacttgctgg atgatgaaga     3000

agttgaagat gaggtgttgt tagatgagga ggatgaagac aatgatatta ctggaaaaac     3060

aggaaaggaa ccagtgacaa gtaatttaca tgaaggaaac cctgaggatg actatgaaga     3120

aaccagtgcc ctggagatga gttgcaagac atccccagtg aggtataaag aggaagaata     3180

taaaagtgga ctttctgctc tagatcatat aaggcacttc acagatagcc tcaaaatgag     3240

gaaaatggaa gataatcaat attctgaagc tgagctgtct tcttttagta cttcccatgt     3300

gccagaggaa cttaagcagc cgttacacag aaagtccaaa tcgcaggcat atgctatgat     3360

gctgtcactg tctgacaagg agtccctcca ttctacatcc cacagttctt ccaacgtgtg     3420

gcacagtatg gccagggctg cggcggaatc cagtgctatc cagtccataa gccacgtatg     3480

acgttatcaa ggttgaccag agtgggacca agtccaacag tagcatggct ctttcatata     3540

ggactattta caagactgct gagcagaatg ccttataaac ctgcagggtc actcatctaa     3600

agtctagtga ccttaaactg aatgatttaa aaaagaaaag aaagaaaaaa gaaactattt     3660

attctcgata ttttgttttg cacagcaaag gcagctgctg acttctggaa gatcaatcaa     3720

tgcgacttaa agtgattcag tgaaaacaaa aaacttggtg ggctgaaggc atcttccagt     3780

ttaccccacc ttagggtatg ggtgggtgag aagggcagtt gagatggcag cattgatatg     3840

aatgaacact ccatagaaac tgaattctct tttgtacaag atcacctgac atgattggga     3900

acagttgctt ttaattacag atttaatttt tttcttcgtt aaagttttat gtaatttaac     3960

cctttgaaga cagaagtagt tggatgaaat gcacagtcaa ttattataga aactgataac     4020

agggagtact tgttccccct tttgccttct taagtacatt gtttaaaact agggaaaaag     4080

ggtatgtgta tattgtaaac tatggatgtt aacactcaaa gaggttaagt cagtgaagta     4140

acctattcat caccagtacc gctgtaccac taataaattg tttgccaaat ccttgtaata     4200

acatcttaat tttagacaat catgtcactg tttttaatgt ttattttttt gtgtgtgttg     4260

cgtgtatcat gtatttattt gttggcaaac tattgtttgt tgattaaaat agcactgttc     4320

cagtcagcca ctactttatg acgtctgagg cacacccctt tccgaatttc aaggaccaag     4380

gtgacccgac ctgtgtatga gagtgccaaa tggtgtttgg cttttcttaa cattcctttt     4440

tgtttgtttg ttttgttttc cttcttaatg aactaaatac gaatagatgc aacttagttt     4500

ttgtaatact gaaatcgatt caattgtata aacgattata atttctttca tggaagcatg     4560

attcttctga ttaaaaactg tactccatat tttatgctgg ttgtctgcaa gcttgtgcga     4620

tgttatgttc atgttaatcc tatttgtaaa atgaagtgtt cccaacctta tgttaaaaga     4680

gagaagtaaa taacagactg tattcagtta ttttgccctt tattgaggaa ccagatttgt     4740

tttctttttg tttgtaatct cattttgaaa taatcagcaa gttgaggtac tttcttcaaa     4800

tgctttgtac aatataaact gttatgcctt tcagtgcatt actatgggag gagcaactaa     4860

aaaataaaga cttacaaaaa ggagtatttt t                                    4891


<210>  1010
<211>  683
<212>  DNA
<213>  homo sapiens

<400>  1010
agcactgcag ggctctgggc gggaaggcta acctggtgcg gagccagcct gggtctcagc       60

cccgcgtacg gcctttcacg agtcttcaag ccttcaggct ttcttctagt caagatgagt      120

gataaaccag acttgtcgga agtggagaag tttgacaggt caaaactgaa gaaaactaat      180

actgaagaaa aaaatactct tccctcaaag gaaactatcc agcaggagaa agagtgtgtt      240

caaacatcat aaaatgggga tctcctccaa agagcagatt tcagcattgc ctgacagtct      300

tggttttagg cttgtttttt tgtaaacctg tgtgtttgta gagatttcag acatcttctg      360

atttcttctc acctatattc cctggttaag aggtcagggg tagtgaatgt ttccttaagt      420

tcctttttaa acttcccatt ggtatgtaaa ttccaaatgg cagatgctgt caataacctt      480

gccatggatg acctttgtgt aggtagtcct tgcacctcat gcaggataag ccaattttaa      540

ctttctacaa tgggtgcctc aatagtttca taatcttcat gaagttgcat cctttggcag      600

cttcttacag tttattttca cttccaatgt agcaataaaa taataaatat aatcgttgtt      660

gtctgaaaaa aaaaaaaaaa aaa                                              683


<210>  1011
<211>  666
<212>  DNA
<213>  homo sapiens

<400>  1011
gggtggctta gcactgcagg gctctgcgcg ggaacgctaa cctggtccgg agcgagtctg       60

ggtctcagcc ccgcgaacag cctttcacga gtcttcaagc tttcaggcta tcttctagtc      120

aagatgagtg ataagccaga cttgtcggaa gtggagaagt ttgacaggtc aaaactgaag      180

aaaactaata ctgaagaaaa aaatactctt ccctcaaagg aaactatcca gcaagagaaa      240

gagtgtgttc aaacatcata aaatggggat cgcctcccaa cagcagattt cgacattacc      300

tgagagtctt gattttaggc ttgttttttg taaacccatg tgtttgtaga gattttaggc      360

gtcttcggat atcttctcac ctatgttccc tggctaagaa gtcagaggta gccaatgttt      420

ccttaaattc atttttaaac ttaccattgg tgcatatgtt ccagatggca gatgctgtca      480

ataatctcac cattgatgac ctttgtgtat gtagttcttg catcctatac tggataagcc      540

tgttttaacc tgctatgatg ggtgcttcca ttgcttcata atcttcatga agttgcatgc      600

ttttgcagct tttcacagtt tatttgcatt tctaatgtag taataaagta accaatataa      660

tcatta                                                                 666


<210>  1012
<211>  3692
<212>  DNA
<213>  homo sapiens

<400>  1012
ggcccgcgga gactccacgg ggcgccccgg gcgtgaggca cccactctgg gagcacagag       60

agctcaggta gcctgcctag atggcggcgc gcaccctggg ccgcggcgtc gggaggctgc      120

tgggcagcct gcgagggctc tcggggcagc ccgcgcggcc gccgtgcggg gtgagcgcgc      180

cgcgcagggc ggcctcggga ccctcgggca gcgctcccgc agttgcagca gcagcagcac      240

agccaggctc gtatcccgcg ctgagtgcac aggcagcccg ggagccggcc gccttctggg      300

ggcctctggc gcgggacact ctcgtgtggg acacccccta ccacaccgtc tgggactgcg      360

acttcagcac tggcaagatc ggctggttcc tgggaggcca gttaaatgtc tctgtcaact      420

gcttggacca gcatgttcgg aagtcccccg agagcgttgc tttgatctgg gagcgcgatg      480

agcctggaac ggaagtgagg atcacctaca gggaactact ggagaccacg tgccgcctgg      540

ccaacacgct gaagaggcat ggagtccacc gtggggaccg tgttgccatc tacatgcccg      600

tgtccccatt ggctgtggca gcaatgctgg cctgtgccag gatcggagct gtccacacag      660

tcatctttgc tggcttcagt gcagagtcct tggctgggag gatcaatgat gccaagtgca      720

aggtggttat caccttcaac caaggactcc ggggtgggcg cgtggtggag ctgaagaaaa      780

tagtggatga ggctgtgaag cactgcccca ccgtgcagca tgtcctggtg gctcacagga      840

cagacaacaa ggtccacatg ggggatctgg acgtcccgct ggagcaggaa atggccaagg      900

aggaccctgt ttgcgcccca gagagcatgg gcagtgagga catgctcttc atgctgtaca      960

cctcagggag caccggaatg cccaagggca tcgtccatac ccaggcaggc tacctgctct     1020

atgccgccct gactcacaag cttgtgtttg accaccagcc aggtgacatc tttggctgtg     1080

tggccgacat cggttggatt acaggacaca gctacgtggt gtatgggcct ctctgcaatg     1140

gtgccaccag cgtccttttt gagagcaccc cagtttatcc caatgctggt cggtactggg     1200

agacagtaga gaggttgaag atcaatcagt tctatggcgc cccaacggct gtccggctgt     1260

tgctgaaata cggtgatgcc tgggtgaaga agtatgatcg ctcctccctg cggaccctgg     1320

ggtcagtggg agagcccatc aactgtgagg cctgggagtg gcttcacagg gtggtggggg     1380

acagcaggtg cacgctggtg gacacctggt ggcagacaga aacaggtggc atctgcatcg     1440

caccacggcc ctcggaagaa ggggcggaaa tcctccctgc catggcgatg aggcccttct     1500

ttggcatcgt ccccgtcctc atggatgaga agggcagcgt cgtggagggc agcaacgtct     1560

ccggggccct gtgcatctcc caggcctggc cgggcatggc caggaccatc tatggcgacc     1620

accagcgatt tgtggacgcc tacttcaagg cctacccagg ctattacttc actggagacg     1680

gggcttaccg aactgagggc ggctattacc agatcacagg gcggatggat gatgtcatca     1740

acatcagtgg ccaccggctg gggaccgcag agattgagga cgccatcgcc gaccaccctg     1800

cagtaccaga aagtgctgtc attggctacc cccacgacat caaaggagaa gctgcctttg     1860

ccttcattgt ggtgaaagat agtgcgggtg actcagatgt ggtggtgcag gagctcaagt     1920

ccatggtggc caccaagatc gccaaatatg ctgtgcctga tgagatcctg gtggtgaaac     1980

gtcttccaaa aaccaggtct gggaaggtca tgcggcggct cctgaggaag atcatcacta     2040

gtgaggccca ggagctggga gacactacca ccttggagga ccccagcatc atcgcagaga     2100

tcctgagtgt ctaccagaag tgcaaggaca agcaggctgc tgctaagtga gctggcacct     2160

tgtggggctc ttgggatggg cgggcaccca agccctggct tgtccttccc agaaggtacc     2220

cctgaggttg gcgtcttcct acgtcccaga agcagccccc accccacaca tgacccacac     2280

cgccctcacg tgaagctggg ctgagagccc tttctcccat ccattggagg tcccaggagt     2340

gtcacccatg gagaggctat gcgacatggc tagggctggt tctgccatct gagtttggtt     2400

tcctggaatg aaaaggcatt gccatctcca ttcctctgcc ctcttgagcc agcacaggaa     2460

ggtgaggccc tgggatagcg cgcctgctca gataacacag agctagttag ctagtagcaa     2520

ccgtgttttc tccagatctg tctagataca aaggtcagaa atcttatttt tatactttta     2580

tattgtggaa gaacagcatg caacactcac atgtagtgtg tggatttact tgaacatgtt     2640

ctttttaaca tgtagttatg aaaatctcct tttttgcctc tactggtgag gaaacatgag     2700

gatcagaggc cacattttta attattgtta gtgtatttgg aagtctgaat tggagatgtt     2760

tgtacctctg tctaaacagt tcccttgaga acttccaagc ctccggcatc ttttcctggt     2820

gagtgtttct cctgtgcttg gttgtgtata atggagctaa ctcctaagcg gtggggtgaa     2880

tgtggccgcc ttagttctga agctactcca gttatgttct gtttcttcaa gctgtgatcc     2940

agaaagattt ttgtgccccc agatgcctct tgataggaga ggcaacatac tccaaatagt     3000

tgggttcttc agggaagcta ttagaaactc aggtgacttg ttagagcact aacttggtca     3060

gagccaaatc ctggcaaacg ctgcctgacc ttcactctgt ggttggggcg gtgagaacca     3120

ctgaggtcca atgatgagac ttggaggtct ggatccagtc tctctttgtt ttaatgtgac     3180

ttaggtgctg tcaacattag caagataatg gaaatcacga cgccagtggg tgcttacctc     3240

cctgctaggc atgcaggggc tggcggttgg caggggaagg aggcccagtg agccgggtcc     3300

cttaggggag ggagagtttg tcctctttgc cccacagtct acccttcagg gccttgtggc     3360

agtgccagtg ttcggggggt gtctgggcca ctgagtaccc actcggtcgt ggttgtgctg     3420

gcctcttggg tgagtgaacc tgtgaagccc aggaggtggt gttggctgca gggtacacaa     3480

atactgagtg gtggtctttt gttacaggct tagcaacaaa gctgtgccct gggcatgggg     3540

ggctgtagtg tagctacagt tgtgcgtttg tgaaatggct tagctttcca tgttgctgag     3600

aggaacctgg acatggtccc gggcatctga atgatctgta ggggagggag ttcaaataaa     3660

gctttatttt gttcattttc tcaaaaaaaa aa                                   3692


<210>  1013
<211>  1798
<212>  DNA
<213>  homo sapiens

<400>  1013
ctctccccgc ccccgcgggg cggcgcgcac tcacccaccc gcgccggagc ggacctttgg       60

cttggcttgt cagggcttgt ccaggagttc cgctcctctc tccaaccggg gtccccctcc      120

agcgacccta aagcttccca gacttccgct tcaattcctg tccgcacccc acgcccacct      180

caacgtggag cgcagtggtc tccgaggagc gccggagctg ccccgcctgc ccagcggggt      240

cagcacttcg catcaaggcc caagaaaagc aagtcctcca gcgttctgag cacccgggcc      300

tgagggaagg tcctaacagc ccccgggagc cagtctccaa cgcctcccgc agcagcccgc      360

cgctcccagg tgcccgcgtg cgccgctgcc gccgcaatcc cgcacgcgtc ccgcgcccgc      420

cccactttgc ctatccccgg gactaagacg ggaatcctgt gaagcagctc cagctatgtg      480

tgaagaagag gacagcactg ccttggtgtg tgacaatggc tctgggctct gtaaggccgg      540

ctttgctggg gacgatgctc ccagggctgt tttcccatcc attgtgggac gtcccagaca      600

tcagggggtg atggtgggaa tgggacaaaa agacagctac gtgggtgacg aagcacagag      660

caaaagagga atcctgaccc tgaagtaccc gatagaacat ggcatcatca ccaactggga      720

cgacatggaa aagatctggc accactcttt ctacaatgag cttcgtgttg cccctgaaga      780

gcatcccacc ctgctcacgg aggcacccct gaaccccaag gccaaccggg agaaaatgac      840

tcaaattatg tttgagactt tcaatgtccc agccatgtat gtggctatcc aggcggtgct      900

gtctctctat gcctctggac gcacaactgg catcgtgctg gactctggag atggtgtcac      960

ccacaatgtc cccatctatg agggctatgc cttgccccat gccatcatgc gtctggatct     1020

ggctggccga gatctcactg actacctcat gaagatcctg actgagcgtg gctattcctt     1080

cgttactact gctgagcgtg agattgtccg ggacatcaag gagaaactgt gttatgtagc     1140

tctggacttt gaaaatgaga tggccactgc cgcatcctca tcctcccttg agaagagtta     1200

cgagttgcct gatgggcaag tgatcaccat cggaaatgaa cgtttccgct gcccagagac     1260

cctgttccag ccatccttca tcgggatgga gtctgctggc atccatgaaa ccacctacaa     1320

cagcatcatg aagtgtgata ttgacatcag gaaggacctc tatgctaaca atgtcctatc     1380

agggggcacc actatgtacc ctggcattgc cgaccgaatg cagaaggaga tcacggccct     1440

agcacccagc accatgaaga tcaagatcat tgcccctccg gagcgcaaat actctgtctg     1500

gatcggtggc tccatcctgg cctctctgtc caccttccag cagatgtgga tcagcaaaca     1560

ggaatacgat gaagccgggc cttccattgt ccaccgcaaa tgcttctaaa acactttcct     1620

gctcctctct gtctctagca cacaactgtg aatgtcctgt ggaattatgc cttcagttct     1680

tttccaaatc attcctagcc aaagctctga ctcgttacct atgtgttttt taataaatct     1740

gaaataggct actggtaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa       1798


<210>  1014
<211>  1415
<212>  DNA
<213>  homo sapiens

<400>  1014
gaggagagca ggccaagggg ctatataacc cttcagcttt cagcttccct gaacaccacc       60

cagtgtggag cagcccagcc aagcactgtc aggaatcctg tgaagcagct ccagctatgt      120

gtgaagaaga ggacagcact gccttggtgt gtgacaatgg ctctgggctc tgtaaggccg      180

gctttgctgg ggacgatgct cccagggctg ttttcccatc cattgtggga cgtcccagac      240

atcagggggt gatggtggga atgggacaaa aagacagcta cgtgggtgac gaagcacaga      300

gcaaaagagg aatcctgacc ctgaagtacc cgatagaaca tggcatcatc accaactggg      360

acgacatgga aaagatctgg caccactctt tctacaatga gcttcgtgtt gcccctgaag      420

agcatcccac cctgctcacg gaggcacccc tgaaccccaa ggccaaccgg gagaaaatga      480

ctcaaattat gtttgagact ttcaatgtcc cagccatgta tgtggctatc caggcggtgc      540

tgtctctcta tgcctctgga cgcacaactg gcatcgtgct ggactctgga gatggtgtca      600

cccacaatgt ccccatctat gagggctatg ccttgcccca tgccatcatg cgtctggatc      660

tggctggccg agatctcact gactacctca tgaagatcct gactgagcgt ggctattcct      720

tcgttactac tgctgagcgt gagattgtcc gggacatcaa ggagaaactg tgttatgtag      780

ctctggactt tgaaaatgag atggccactg ccgcatcctc atcctccctt gagaagagtt      840

acgagttgcc tgatgggcaa gtgatcacca tcggaaatga acgtttccgc tgcccagaga      900

ccctgttcca gccatccttc atcgggatgg agtctgctgg catccatgaa accacctaca      960

acagcatcat gaagtgtgat attgacatca ggaaggacct ctatgctaac aatgtcctat     1020

cagggggcac cactatgtac cctggcattg ccgaccgaat gcagaaggag atcacggccc     1080

tagcacccag caccatgaag atcaagatca ttgcccctcc ggagcgcaaa tactctgtct     1140

ggatcggtgg ctccatcctg gcctctctgt ccaccttcca gcagatgtgg atcagcaaac     1200

aggaatacga tgaagccggg ccttccattg tccaccgcaa atgcttctaa aacactttcc     1260

tgctcctctc tgtctctagc acacaactgt gaatgtcctg tggaattatg ccttcagttc     1320

ttttccaaat cattcctagc caaagctctg actcgttacc tatgtgtttt ttaataaatc     1380

tgaaataggc tactggtaaa aaaaaaaaaa aaaaa                                1415


<210>  1015
<211>  1096
<212>  DNA
<213>  homo sapiens

<400>  1015
agacccgccc gcccgagccg gagttacaag agccgcctcc gcgcacgggg gcccggccac       60

tcggagctgc tctgccgcgg ggactgcacc gcccgccctg ccagacccgc ccggaacggg      120

gctcgtcgcc gccagtagcc gcagcaccgc agccttgggc ctcgcgccgg ctatggccgt      180

gccctggggc tgagccctca ggttgtgacc gagattcccg acgagagaga ctgaggggaa      240

gagaggaagg aggggcgggc tcctggcaag gcattcgctc ctgagcggaa tcctgcaaag      300

atggagaagg aggagacaac ccgggagctg ctgctgccca actggcaggg tagtggctcc      360

cacgggctga ccatcgccca gagggacgac ggcgtctttg tgcaggaggt gacgcagaac      420

tcccctgcgg cccgcactgg ggtggtcaag gagggggacc agattgtggg tgccaccatc      480

tactttgaca acctgcagtc gggtgaggtg acccagctgc tgaacaccat ggggcaccac      540

acggtgggcc tgaagctgca ccgcaagggg gaccgctctc ccgagcctgg ccagacctgg      600

acccgtgaag tcttcagctc ctgcagctct gaagtggttc tgaacacacc acagccatca      660

gcactggaat gcaaagacca gaacaaacag aaggaagcca gcagccaagc cggggcagtt      720

tcagtctcca ccccaaatgc aggactgtag aagcggccag gaagaaaacc accccctctt      780

aaggttgttt ttgtgaccgt tctttggagc attgttctaa aaatgggaaa ttacatattg      840

ctgtgccaag ggcaacaaac acctgcagtt aaaggaatac cttccgcgag gcggcttttc      900

ggagcatgca tgtttatagc tccagccagg ccagaccgag ggctgctgca taagccctgc      960

ttggtgcatt tctttacttg caaggggaca gagtgtgggc ttaggtttgg gactagaggg     1020

ggctttggca actatggtgc tcaggtgatt atccttcgct cgtttatcca ataaacattt     1080

atcaagcatc tgaaaa                                                     1096


<210>  1016
<211>  2473
<212>  DNA
<213>  homo sapiens

<400>  1016
aattactgca gttgtctgta ggagaaaggg ctcattgtgg tttttctcga ctacctttct       60

taaagacata tgcaaatagc cagacagaac acatggcact gacctatggc cagggactca      120

cagttttgtg agaatacggg agcgtatagc cacttccttc actgaatgcc agtcccagag      180

cagttgcatt aggctggagg actggaggtg gagccttttt tgctcacggc agcaagttcc      240

cttctccttt ctctcccccg gcggcgtgtg cattggctct tcaagctgcc tgtgctgctc      300

cgtggagtga aaaaggcagg gtgtgctcgc agactgtgct ataaactgca atttctattt      360

ggggtcctca cggagaagaa caccaggaaa gacagacagg accagtgcca tgggccagct      420

ttgctgcttt cctttctcaa gagatgaagg aaaaatcagt gaaaagaacg gaggggagcc      480

cgatgacgct gaactagtaa ggctcagtaa gaggctggtg gagaacgcgg tgctcaaggc      540

tgtccagcag tatctggagg aaacacagaa taaaaacaag ccgggggagg ggagctctgt      600

gaaaaccgaa gcagctgatc agaatggcaa tgacaatgag aacaacagga aatgagcccg      660

gaacgcaggc ccccatgtct ctgtgcaaag cctccctgct tccctctgct gagtctaggg      720

actgacttgc agcgtgctgt ttaagttaag tttctctggt gcaatctgtg aagattgcct      780

aatacttttc atgatcgatg tgttcgcatt gctgaaacac aacagaagaa aaatggagtg      840

ctgggactgg cagaggaaat taattgatga aagaagaatg gcccaagttt cattcgccct      900

cagccacgca caagggaaag ggaactttgg gttatgcctc ctggacgcaa attaaaggcc      960

gagaaagagg ccttgccatc aatggaatac tgccatttat attgcttagc agggcatttg     1020

actactttat ctgaggccag aactctcaca cacagctatc aagtgctaag tttaaaataa     1080

tcactgttgg aattgtcatc tgtacaatta gtccataatg tttcatgttt gtcctaagtg     1140

tgctgttgct atgcagtgtg atctttattt atagtaaatt atgtttcatg taaatgatat     1200

atttttggtg aaatgcaacc ttttctataa aatgtgggca acattttaaa gtttttttaa     1260

aatcctattt tgataagtca gtatgccata tttaatgaaa tgttattata taattttttt     1320

ttcttaggca agaaacctat tggaattcga gacttaatta atgaagcttt gcatcgagaa     1380

acgatgggtc tgaagtccaa agtgaaacag ataaaggaac ttttattaaa gcctgagact     1440

caggccagaa ttaggaggga gctttttgaa ggaagactta ttaacaacag taattcagca     1500

aatgacgttg atttcagcac aactttgaca taagctctac attgcgattg tgacaacata     1560

gcttatgaaa tcttttcagc ttattaagta gctctttggt aaacaccaaa gaagtttctg     1620

atagtgtctg cacaacagca aaccaacatt tggtgaggaa ttagcaattt cttgccaaag     1680

aaaattgatt ctgcccaatt attttttgag ctacacttgt gttttagaat atctgtttct     1740

gtaatattga gagttatttt atagaaatga tttcttaatt agctgttgtg agatatttct     1800

cgggtccttg cagaaaaaaa catacagact gtgaacaaat cattcacaaa cagaataaaa     1860

cagagccaac aacagtattt taagggtcac ttgcctcctg ttgacacaat tgttgctaaa     1920

tcaaaagaag cgttgtccag gtgtgtctac atctagtgtt acttttaatg agaatttgaa     1980

tgtttattga acaatagtac ttgaatgaac atttataaat gtaattattg cgatcactgg     2040

ttaagaatgt tttatatatc cttataatat ttttcactga tcaaaatgtt gttctgcttt     2100

ttcatttctt aaggaataca tgtttgggat ttttattttt tacgtgtccg aagataagct     2160

ccaggtctta tcgtatccct tgccatctga acttgtttgc actgcttctg tttgaaagag     2220

catcttgaaa aacttccccg gtatgatgat tgttggtaac aactttttct atagtcattg     2280

atggagtaga tcatgatgga ggggaaatca ctggagatca aatatgtaaa atcatttcaa     2340

atataaaatc cagtttactc atggatttta gctatttttt cactgggtaa attatactac     2400

atttatttac aaatgagttt atgcattttc atggctctta ataaacatat tgttttccct     2460

tgttaaaaaa aaa                                                        2473


<210>  1017
<211>  2542
<212>  DNA
<213>  homo sapiens

<400>  1017
aattactgca gttgtctgta ggagaaaggg ctcattgtgg tttttctcga ctacctttct       60

taaagacata tgcaaatagc cagacagaac acatggcact gacctatggc cagggactca      120

cagttttgtg agaatacggg agcgtatagc cacttccttc actgaatgcc agtcccagag      180

cagttgcatt aggctggagg actggaggtg gagccttttt tgctcacggc agcaagttcc      240

cttctccttt ctctcccccg gcggcgtgtg cattggctct tcaagctgcc tgtgctgctc      300

cgtggagtga aaaaggcagg gtgtgctcgc agactgtgct ataaactgca atttctattt      360

ggggtcctca cggagaagaa caccaggaaa gacagacagg accagtgcca tgggccagct      420

ttgctgcttt cctttctcaa gagatgaagg aaaaatcagt gagttggaaa gctcgtcctc      480

tgcagtccta cagagataca gcaaggatat acccagttgg tcaagtggtg aaaagaacgg      540

aggggagccc gatgacgctg aactagtaag gctcagtaag aggctggtgg agaacgcggt      600

gctcaaggct gtccagcagt atctggagga aacacagaat aaaaacaagc cgggggaggg      660

gagctctgtg aaaaccgaag cagctgatca gaatggcaat gacaatgaga acaacaggaa      720

atgagcccgg aacgcaggcc cccatgtctc tgtgcaaagc ctccctgctt ccctctgctg      780

agtctaggga ctgacttgca gcgtgctgtt taagttaagt ttctctggtg caatctgtga      840

agattgccta atacttttca tgatcgatgt gttcgcattg ctgaaacaca acagaagaaa      900

aatggagtgc tgggactggc agaggaaatt aattgatgaa agaagaatgg cccaagtttc      960

attcgccctc agccacgcac aagggaaagg gaactttggg ttatgcctcc tggacgcaaa     1020

ttaaaggccg agaaagaggc cttgccatca atggaatact gccatttata ttgcttagca     1080

gggcatttga ctactttatc tgaggccaga actctcacac acagctatca agtgctaagt     1140

ttaaaataat cactgttgga attgtcatct gtacaattag tccataatgt ttcatgtttg     1200

tcctaagtgt gctgttgcta tgcagtgtga tctttattta tagtaaatta tgtttcatgt     1260

aaatgatata tttttggtga aatgcaacct tttctataaa atgtgggcaa cattttaaag     1320

tttttttaaa atcctatttt gataagtcag tatgccatat ttaatgaaat gttattatat     1380

aatttttttt tcttaggcaa gaaacctatt ggaattcgag acttaattaa tgaagctttg     1440

catcgagaaa cgatgggtct gaagtccaaa gtgaaacaga taaaggaact tttattaaag     1500

cctgagactc aggccagaat taggagggag ctttttgaag gaagacttat taacaacagt     1560

aattcagcaa atgacgttga tttcagcaca actttgacat aagctctaca ttgcgattgt     1620

gacaacatag cttatgaaat cttttcagct tattaagtag ctctttggta aacaccaaag     1680

aagtttctga tagtgtctgc acaacagcaa accaacattt ggtgaggaat tagcaatttc     1740

ttgccaaaga aaattgattc tgcccaatta ttttttgagc tacacttgtg ttttagaata     1800

tctgtttctg taatattgag agttatttta tagaaatgat ttcttaatta gctgttgtga     1860

gatatttctc gggtccttgc agaaaaaaac atacagactg tgaacaaatc attcacaaac     1920

agaataaaac agagccaaca acagtatttt aagggtcact tgcctcctgt tgacacaatt     1980

gttgctaaat caaaagaagc gttgtccagg tgtgtctaca tctagtgtta cttttaatga     2040

gaatttgaat gtttattgaa caatagtact tgaatgaaca tttataaatg taattattgc     2100

gatcactggt taagaatgtt ttatatatcc ttataatatt tttcactgat caaaatgttg     2160

ttctgctttt tcatttctta aggaatacat gtttgggatt tttatttttt acgtgtccga     2220

agataagctc caggtcttat cgtatccctt gccatctgaa cttgtttgca ctgcttctgt     2280

ttgaaagagc atcttgaaaa acttccccgg tatgatgatt gttggtaaca actttttcta     2340

tagtcattga tggagtagat catgatggag gggaaatcac tggagatcaa atatgtaaaa     2400

tcatttcaaa tataaaatcc agtttactca tggattttag ctattttttc actgggtaaa     2460

ttatactaca tttatttaca aatgagttta tgcattttca tggctcttaa taaacatatt     2520

gttttccctt gttaaaaaaa aa                                              2542


<210>  1018
<211>  2943
<212>  DNA
<213>  homo sapiens

<400>  1018
ctcgcctcca gccccgggac gcggcccgcc accgccgctg ccgccagccc agacgcgccg       60

cccgcatgcg ccgcgaccat ggagcgcccc gaagcgggag gaattaattc caatgagtgt      120

gaaaatgtat caagaaaaaa gaaaatgtca gaggaatttg aagccaatac tatggattct      180

ctggtagaca tgccatttgc tactgtagat attcaggatg actgtggaat cactgatgaa      240

cctcaaataa atttgaagag aagtcaagaa aatgaatggg tcaagagtga tcaagtaaag      300

aagaggaaaa aaaagagaaa agattatcaa cccaactatt tcctgtccat tccaatcacc      360

aacaaagaga ttataaaagg aattaagatc ctgcagaatg caataataca acaagatgag      420

cgactggcca aagcaatggt cagtgatggt tcctttcata ttaccctgct ggtgatgcaa      480

ttattaaatg aagatgaagt aaacattggt attgatgctc ttttggaatt gaaaccattc      540

atagaagaac tcctccaggg aaaacatttg actttgccct ttcaagggat tggtactttt      600

ggaaatcagg ttggatttgt gaagctggca gaaggagatc atgtaaactc acttttggag      660

atagcagaga ctgcaaatag gacatttcaa gaaaaaggca tcctggtagg agagagcaga      720

agttttaaac ctcatttgac cttcatgaag ttgtcaaaat caccgtggct ccgtaagaat      780

ggagtgaaaa aaatagatcc tgatttatat gaaaagttta tcagtcacag atttggagaa      840

gaaatattat atcgcataga tctttgctcc atgctgaaga aaaaacaaag taatggttat      900

tatcactgtg aatcttccat tgtgattggt gaaaagaacg gaggggagcc cgatgacgct      960

gaactagtaa ggctcagtaa gaggctggtg gagaacgcgg tgctcaaggc tgtccagcag     1020

tatctggagg aaacacagaa taaaaacaag ccgggggagg ggagctctgt gaaaaccgaa     1080

gcagctgatc agaatggcaa tgacaatgag aacaacagga aatgagcccg gaacgcaggc     1140

ccccatgtct ctgtgcaaag cctccctgct tccctctgct gagtctaggg actgacttgc     1200

agcgtgctgt ttaagttaag tttctctggt gcaatctgtg aagattgcct aatacttttc     1260

atgatcgatg tgttcgcatt gctgaaacac aacagaagaa aaatggagtg ctgggactgg     1320

cagaggaaat taattgatga aagaagaatg gcccaagttt cattcgccct cagccacgca     1380

caagggaaag ggaactttgg gttatgcctc ctggacgcaa attaaaggcc gagaaagagg     1440

ccttgccatc aatggaatac tgccatttat attgcttagc agggcatttg actactttat     1500

ctgaggccag aactctcaca cacagctatc aagtgctaag tttaaaataa tcactgttgg     1560

aattgtcatc tgtacaatta gtccataatg tttcatgttt gtcctaagtg tgctgttgct     1620

atgcagtgtg atctttattt atagtaaatt atgtttcatg taaatgatat atttttggtg     1680

aaatgcaacc ttttctataa aatgtgggca acattttaaa gtttttttaa aatcctattt     1740

tgataagtca gtatgccata tttaatgaaa tgttattata taattttttt ttcttaggca     1800

agaaacctat tggaattcga gacttaatta atgaagcttt gcatcgagaa acgatgggtc     1860

tgaagtccaa agtgaaacag ataaaggaac ttttattaaa gcctgagact caggccagaa     1920

ttaggaggga gctttttgaa ggaagactta ttaacaacag taattcagca aatgacgttg     1980

atttcagcac aactttgaca taagctctac attgcgattg tgacaacata gcttatgaaa     2040

tcttttcagc ttattaagta gctctttggt aaacaccaaa gaagtttctg atagtgtctg     2100

cacaacagca aaccaacatt tggtgaggaa ttagcaattt cttgccaaag aaaattgatt     2160

ctgcccaatt attttttgag ctacacttgt gttttagaat atctgtttct gtaatattga     2220

gagttatttt atagaaatga tttcttaatt agctgttgtg agatatttct cgggtccttg     2280

cagaaaaaaa catacagact gtgaacaaat cattcacaaa cagaataaaa cagagccaac     2340

aacagtattt taagggtcac ttgcctcctg ttgacacaat tgttgctaaa tcaaaagaag     2400

cgttgtccag gtgtgtctac atctagtgtt acttttaatg agaatttgaa tgtttattga     2460

acaatagtac ttgaatgaac atttataaat gtaattattg cgatcactgg ttaagaatgt     2520

tttatatatc cttataatat ttttcactga tcaaaatgtt gttctgcttt ttcatttctt     2580

aaggaataca tgtttgggat ttttattttt tacgtgtccg aagataagct ccaggtctta     2640

tcgtatccct tgccatctga acttgtttgc actgcttctg tttgaaagag catcttgaaa     2700

aacttccccg gtatgatgat tgttggtaac aactttttct atagtcattg atggagtaga     2760

tcatgatgga ggggaaatca ctggagatca aatatgtaaa atcatttcaa atataaaatc     2820

cagtttactc atggatttta gctatttttt cactgggtaa attatactac atttatttac     2880

aaatgagttt atgcattttc atggctctta ataaacatat tgttttccct tgttaaaaaa     2940

aaa                                                                   2943


<210>  1019
<211>  2473
<212>  DNA
<213>  homo sapiens

<400>  1019
aattactgca gttgtctgta ggagaaaggg ctcattgtgg tttttctcga ctacctttct       60

taaagacata tgcaaatagc cagacagaac acatggcact gacctatggc cagggactca      120

cagttttgtg agaatacggg agcgtatagc cacttccttc actgaatgcc agtcccagag      180

cagttgcatt aggctggagg actggaggtg gagccttttt tgctcacggc agcaagttcc      240

cttctccttt ctctcccccg gcggcgtgtg cattggctct tcaagctgcc tgtgctgctc      300

cgtggagtga aaaaggcagg gtgtgctcgc agactgtgct ataaactgca atttctattt      360

ggggtcctca cggagaagaa caccaggaaa gacagacagg accagtgcca tgggccagct      420

ttgctgcttt cctttctcaa gagatgaagg aaaaatcagt gaaaagaacg gaggggagcc      480

cgatgacgct gaactagtaa ggctcagtaa gaggctggtg gagaacgcgg tgctcaaggc      540

tgtccagcag tatctggagg aaacacagaa taaaaacaag ccgggggagg ggagctctgt      600

gaaaaccgaa gcagctgatc agaatggcaa tgacaatgag aacaacagga aatgagcccg      660

gaacgcaggc ccccatgtct ctgtgcaaag cctccctgct tccctctgct gagtctaggg      720

actgacttgc agcgtgctgt ttaagttaag tttctctggt gcaatctgtg aagattgcct      780

aatacttttc atgatcgatg tgttcgcatt gctgaaacac aacagaagaa aaatggagtg      840

ctgggactgg cagaggaaat taattgatga aagaagaatg gcccaagttt cattcgccct      900

cagccacgca caagggaaag ggaactttgg gttatgcctc ctggacgcaa attaaaggcc      960

gagaaagagg ccttgccatc aatggaatac tgccatttat attgcttagc agggcatttg     1020

actactttat ctgaggccag aactctcaca cacagctatc aagtgctaag tttaaaataa     1080

tcactgttgg aattgtcatc tgtacaatta gtccataatg tttcatgttt gtcctaagtg     1140

tgctgttgct atgcagtgtg atctttattt atagtaaatt atgtttcatg taaatgatat     1200

atttttggtg aaatgcaacc ttttctataa aatgtgggca acattttaaa gtttttttaa     1260

aatcctattt tgataagtca gtatgccata tttaatgaaa tgttattata taattttttt     1320

ttcttaggca agaaacctat tggaattcga gacttaatta atgaagcttt gcatcgagaa     1380

acgatgggtc tgaagtccaa agtgaaacag ataaaggaac ttttattaaa gcctgagact     1440

caggccagaa ttaggaggga gctttttgaa ggaagactta ttaacaacag taattcagca     1500

aatgacgttg atttcagcac aactttgaca taagctctac attgcgattg tgacaacata     1560

gcttatgaaa tcttttcagc ttattaagta gctctttggt aaacaccaaa gaagtttctg     1620

atagtgtctg cacaacagca aaccaacatt tggtgaggaa ttagcaattt cttgccaaag     1680

aaaattgatt ctgcccaatt attttttgag ctacacttgt gttttagaat atctgtttct     1740

gtaatattga gagttatttt atagaaatga tttcttaatt agctgttgtg agatatttct     1800

cgggtccttg cagaaaaaaa catacagact gtgaacaaat cattcacaaa cagaataaaa     1860

cagagccaac aacagtattt taagggtcac ttgcctcctg ttgacacaat tgttgctaaa     1920

tcaaaagaag cgttgtccag gtgtgtctac atctagtgtt acttttaatg agaatttgaa     1980

tgtttattga acaatagtac ttgaatgaac atttataaat gtaattattg cgatcactgg     2040

ttaagaatgt tttatatatc cttataatat ttttcactga tcaaaatgtt gttctgcttt     2100

ttcatttctt aaggaataca tgtttgggat ttttattttt tacgtgtccg aagataagct     2160

ccaggtctta tcgtatccct tgccatctga acttgtttgc actgcttctg tttgaaagag     2220

catcttgaaa aacttccccg gtatgatgat tgttggtaac aactttttct atagtcattg     2280

atggagtaga tcatgatgga ggggaaatca ctggagatca aatatgtaaa atcatttcaa     2340

atataaaatc cagtttactc atggatttta gctatttttt cactgggtaa attatactac     2400

atttatttac aaatgagttt atgcattttc atggctctta ataaacatat tgttttccct     2460

tgttaaaaaa aaa                                                        2473


<210>  1020
<211>  2542
<212>  DNA
<213>  homo sapiens

<400>  1020
aattactgca gttgtctgta ggagaaaggg ctcattgtgg tttttctcga ctacctttct       60

taaagacata tgcaaatagc cagacagaac acatggcact gacctatggc cagggactca      120

cagttttgtg agaatacggg agcgtatagc cacttccttc actgaatgcc agtcccagag      180

cagttgcatt aggctggagg actggaggtg gagccttttt tgctcacggc agcaagttcc      240

cttctccttt ctctcccccg gcggcgtgtg cattggctct tcaagctgcc tgtgctgctc      300

cgtggagtga aaaaggcagg gtgtgctcgc agactgtgct ataaactgca atttctattt      360

ggggtcctca cggagaagaa caccaggaaa gacagacagg accagtgcca tgggccagct      420

ttgctgcttt cctttctcaa gagatgaagg aaaaatcagt gagttggaaa gctcgtcctc      480

tgcagtccta cagagataca gcaaggatat acccagttgg tcaagtggtg aaaagaacgg      540

aggggagccc gatgacgctg aactagtaag gctcagtaag aggctggtgg agaacgcggt      600

gctcaaggct gtccagcagt atctggagga aacacagaat aaaaacaagc cgggggaggg      660

gagctctgtg aaaaccgaag cagctgatca gaatggcaat gacaatgaga acaacaggaa      720

atgagcccgg aacgcaggcc cccatgtctc tgtgcaaagc ctccctgctt ccctctgctg      780

agtctaggga ctgacttgca gcgtgctgtt taagttaagt ttctctggtg caatctgtga      840

agattgccta atacttttca tgatcgatgt gttcgcattg ctgaaacaca acagaagaaa      900

aatggagtgc tgggactggc agaggaaatt aattgatgaa agaagaatgg cccaagtttc      960

attcgccctc agccacgcac aagggaaagg gaactttggg ttatgcctcc tggacgcaaa     1020

ttaaaggccg agaaagaggc cttgccatca atggaatact gccatttata ttgcttagca     1080

gggcatttga ctactttatc tgaggccaga actctcacac acagctatca agtgctaagt     1140

ttaaaataat cactgttgga attgtcatct gtacaattag tccataatgt ttcatgtttg     1200

tcctaagtgt gctgttgcta tgcagtgtga tctttattta tagtaaatta tgtttcatgt     1260

aaatgatata tttttggtga aatgcaacct tttctataaa atgtgggcaa cattttaaag     1320

tttttttaaa atcctatttt gataagtcag tatgccatat ttaatgaaat gttattatat     1380

aatttttttt tcttaggcaa gaaacctatt ggaattcgag acttaattaa tgaagctttg     1440

catcgagaaa cgatgggtct gaagtccaaa gtgaaacaga taaaggaact tttattaaag     1500

cctgagactc aggccagaat taggagggag ctttttgaag gaagacttat taacaacagt     1560

aattcagcaa atgacgttga tttcagcaca actttgacat aagctctaca ttgcgattgt     1620

gacaacatag cttatgaaat cttttcagct tattaagtag ctctttggta aacaccaaag     1680

aagtttctga tagtgtctgc acaacagcaa accaacattt ggtgaggaat tagcaatttc     1740

ttgccaaaga aaattgattc tgcccaatta ttttttgagc tacacttgtg ttttagaata     1800

tctgtttctg taatattgag agttatttta tagaaatgat ttcttaatta gctgttgtga     1860

gatatttctc gggtccttgc agaaaaaaac atacagactg tgaacaaatc attcacaaac     1920

agaataaaac agagccaaca acagtatttt aagggtcact tgcctcctgt tgacacaatt     1980

gttgctaaat caaaagaagc gttgtccagg tgtgtctaca tctagtgtta cttttaatga     2040

gaatttgaat gtttattgaa caatagtact tgaatgaaca tttataaatg taattattgc     2100

gatcactggt taagaatgtt ttatatatcc ttataatatt tttcactgat caaaatgttg     2160

ttctgctttt tcatttctta aggaatacat gtttgggatt tttatttttt acgtgtccga     2220

agataagctc caggtcttat cgtatccctt gccatctgaa cttgtttgca ctgcttctgt     2280

ttgaaagagc atcttgaaaa acttccccgg tatgatgatt gttggtaaca actttttcta     2340

tagtcattga tggagtagat catgatggag gggaaatcac tggagatcaa atatgtaaaa     2400

tcatttcaaa tataaaatcc agtttactca tggattttag ctattttttc actgggtaaa     2460

ttatactaca tttatttaca aatgagttta tgcattttca tggctcttaa taaacatatt     2520

gttttccctt gttaaaaaaa aa                                              2542


<210>  1021
<211>  2441
<212>  DNA
<213>  homo sapiens

<400>  1021
ccgggcctca ctcgggcccc gcggccgcct ttataaggcg gcgggggtgg tggcccgggc       60

cgcgttgcgc tcccgccact ccgcgcccgc tatcctggct ccgtgctccc acgcgcttgt      120

gcctggacgg accctcgcca gtgctctgcg cagagaaaga gaaagacccc aagtactggc      180

gagaccaagc gcaagagaca ctgaaatatg ccctggagct tcagaagctc aacaccaacg      240

tggctaagaa tgtcatcatg ttcctgggag atgggatggg tgtctccaca gtgacggctg      300

cccgcatcct caagggtcag ctccaccaca accctgggga ggagaccagg ctggagatgg      360

acaagttccc cttcgtggcc ctctccaaga cgtacaacac caatgcccag gtccctgaca      420

gcgccggcac cgccaccgcc tacctgtgtg gggtgaaggc caatgagggc accgtggggg      480

taagcgcagc cactgagcgt tcccggtgca acaccaccca ggggaacgag gtcacctcca      540

tcctgcgctg ggccaaggac gctgggaaat ctgtgggcat tgtgaccacc acgagagtga      600

accatgccac ccccagcgcc gcctacgccc actcggctga ccgggactgg tactcagaca      660

acgagatgcc ccctgaggcc ttgagccagg gctgtaagga catcgcctac cagctcatgc      720

ataacatcag ggacattgac gtgatcatgg ggggtggccg gaaatacatg taccccaaga      780

ataaaactga tgtggagtat gagagtgacg agaaagccag gggcacgagg ctggacggcc      840

tggacctcgt tgacacctgg aagagcttca aaccgagata caagcactcc cacttcatct      900

ggaaccgcac ggaactcctg acccttgacc cccacaatgt ggactaccta ttgggtctct      960

tcgagccagg ggacatgcag tacgagctga acaggaacaa cgtgacggac ccgtcactct     1020

ccgagatggt ggtggtggcc atccagatcc tgcggaagaa ccccaaaggc ttcttcttgc     1080

tggtggaagg aggcagaatt gaccacgggc accatgaagg aaaagccaag caggccctgc     1140

atgaggcggt ggagatggac cgggccatcg ggcaggcagg cagcttgacc tcctcggaag     1200

acactctgac cgtggtcact gcggaccatt cccacgtctt cacatttggt ggatacaccc     1260

cccgtggcaa ctctatcttt ggtctggccc ccatgctgag tgacacagac aagaagccct     1320

tcactgccat cctgtatggc aatgggcctg gctacaaggt ggtgggcggt gaacgagaga     1380

atgtctccat ggtggactat gctcacaaca actaccaggc gcagtctgct gtgcccctgc     1440

gccacgagac ccacggcggg gaggacgtgg ccgtcttctc caagggcccc atggcgcacc     1500

tgctgcacgg cgtccacgag cagaactacg tcccccacgt gatggcgtat gcagcctgca     1560

tcggggccaa cctcggccac tgtgctcctg ccagctcggc aggcagcctt gctgcaggcc     1620

ccctgctgct cgcgctggcc ctctaccccc tgagcgtcct gttctgaggg cccagggccc     1680

gggcacccac aagcccgtga cagatgccaa cttcccacac ggcagccccc ccctcaaggg     1740

gcagggaggt gggggcctcc tcagcctctg caactgcaag aaaggggacc caagaaacca     1800

aagtctgccg cccacctcgc tcccctctgg aatcttcccc aagggccaaa cccacttctg     1860

gcctccagcc tttgctccct ccccgctgcc ctttggccaa cagggtagat ttctcttggg     1920

caggcagaga gtacagactg cagacattct caaagcctct tatttttcta gcgaacgtat     1980

ttctccagac ccagaggccc tgaagcctcc gtggaacatt ctggatctga ccctcccagt     2040

ctcatctcct gaccctccca ctcccatctc cttacctctg gaacccccca ggccctacaa     2100

tgctcatgtc cctgtcccca ggcccagccc tccttcaggg gagttgaggt ctttctcctc     2160

aggacaaggc cttgctcact cactcactcc aagaccacca gggtcccagg aagccggtgc     2220

ctgggtggcc atcctaccca gcgtggccca ggccgggaag agccacctgg cagggctcac     2280

actcctgggc tctgaacaca cacgccagct cctctctgaa gcgactctcc tgtttggaac     2340

ggcaaaaaaa aatttttttt tctctttttg gtggtggtta aaagggaaca caaaacattt     2400

aaataaaact ttccaaatat ttccgaggac aaaaaaaaaa a                         2441


<210>  1022
<211>  2606
<212>  DNA
<213>  homo sapiens

<400>  1022
ccgggcctca ctcgggcccc gcggccgcct ttataaggcg gcgggggtgg tggcccgggc       60

cgcgttgcgc tcccgccact ccgcgcccgc tatcctggct ccgtgctccc acgcgcttgt      120

gcctggacgg accctcgcca gtgctctgcg caggattgga acatcagtta acatctgacc      180

actgccagcc caccccctcc cacccacgtc gattgcatct ctgggctcca gggataaagc      240

aggtcttggg gtgcaccatg atttcaccat tcttagtact ggccattggc acctgcctta      300

ctaactcctt agtgccagag aaagagaaag accccaagta ctggcgagac caagcgcaag      360

agacactgaa atatgccctg gagcttcaga agctcaacac caacgtggct aagaatgtca      420

tcatgttcct gggagatggg atgggtgtct ccacagtgac ggctgcccgc atcctcaagg      480

gtcagctcca ccacaaccct ggggaggaga ccaggctgga gatggacaag ttccccttcg      540

tggccctctc caagacgtac aacaccaatg cccaggtccc tgacagcgcc ggcaccgcca      600

ccgcctacct gtgtggggtg aaggccaatg agggcaccgt gggggtaagc gcagccactg      660

agcgttcccg gtgcaacacc acccagggga acgaggtcac ctccatcctg cgctgggcca      720

aggacgctgg gaaatctgtg ggcattgtga ccaccacgag agtgaaccat gccaccccca      780

gcgccgccta cgcccactcg gctgaccggg actggtactc agacaacgag atgccccctg      840

aggccttgag ccagggctgt aaggacatcg cctaccagct catgcataac atcagggaca      900

ttgacgtgat catggggggt ggccggaaat acatgtaccc caagaataaa actgatgtgg      960

agtatgagag tgacgagaaa gccaggggca cgaggctgga cggcctggac ctcgttgaca     1020

cctggaagag cttcaaaccg agatacaagc actcccactt catctggaac cgcacggaac     1080

tcctgaccct tgacccccac aatgtggact acctattggg tctcttcgag ccaggggaca     1140

tgcagtacga gctgaacagg aacaacgtga cggacccgtc actctccgag atggtggtgg     1200

tggccatcca gatcctgcgg aagaacccca aaggcttctt cttgctggtg gaaggaggca     1260

gaattgacca cgggcaccat gaaggaaaag ccaagcaggc cctgcatgag gcggtggaga     1320

tggaccgggc catcgggcag gcaggcagct tgacctcctc ggaagacact ctgaccgtgg     1380

tcactgcgga ccattcccac gtcttcacat ttggtggata caccccccgt ggcaactcta     1440

tctttggtct ggcccccatg ctgagtgaca cagacaagaa gcccttcact gccatcctgt     1500

atggcaatgg gcctggctac aaggtggtgg gcggtgaacg agagaatgtc tccatggtgg     1560

actatgctca caacaactac caggcgcagt ctgctgtgcc cctgcgccac gagacccacg     1620

gcggggagga cgtggccgtc ttctccaagg gccccatggc gcacctgctg cacggcgtcc     1680

acgagcagaa ctacgtcccc cacgtgatgg cgtatgcagc ctgcatcggg gccaacctcg     1740

gccactgtgc tcctgccagc tcggcaggca gccttgctgc aggccccctg ctgctcgcgc     1800

tggccctcta ccccctgagc gtcctgttct gagggcccag ggcccgggca cccacaagcc     1860

cgtgacagat gccaacttcc cacacggcag cccccccctc aaggggcagg gaggtggggg     1920

cctcctcagc ctctgcaact gcaagaaagg ggacccaaga aaccaaagtc tgccgcccac     1980

ctcgctcccc tctggaatct tccccaaggg ccaaacccac ttctggcctc cagcctttgc     2040

tccctccccg ctgccctttg gccaacaggg tagatttctc ttgggcaggc agagagtaca     2100

gactgcagac attctcaaag cctcttattt ttctagcgaa cgtatttctc cagacccaga     2160

ggccctgaag cctccgtgga acattctgga tctgaccctc ccagtctcat ctcctgaccc     2220

tcccactccc atctccttac ctctggaacc ccccaggccc tacaatgctc atgtccctgt     2280

ccccaggccc agccctcctt caggggagtt gaggtctttc tcctcaggac aaggccttgc     2340

tcactcactc actccaagac caccagggtc ccaggaagcc ggtgcctggg tggccatcct     2400

acccagcgtg gcccaggccg ggaagagcca cctggcaggg ctcacactcc tgggctctga     2460

acacacacgc cagctcctct ctgaagcgac tctcctgttt ggaacggcaa aaaaaaattt     2520

ttttttctct ttttggtggt ggttaaaagg gaacacaaaa catttaaata aaactttcca     2580

aatatttccg aggacaaaaa aaaaaa                                          2606


<210>  1023
<211>  4499
<212>  DNA
<213>  homo sapiens

<400>  1023
aggcagggcg cgggcagccc ggcgcggggt cctgggacgg gcgcggcgcg gggcgcgggc       60

ttctcggcgg ctgcggcccg ggcggcggcg atgctgtggc cgcggctggc ggcggccgag      120

tgggcggcgc tggcctggga gctgctgggc gcctcggtgc tgctgatcgc tgtgcggtgg      180

ctggtgcggc ggctgggccc gcggccggga ggtctgggcc gcagcgggac cccagttcct      240

ccgccaagcg cggccgccgc ccccgcctca ggtgaaatga caatggatgc tctgttggct      300

cgattgaaac ttctgaatcc agatgacctt agagaagaaa tcgtcaaagc cggattgaaa      360

tgtggaccca ttacatcaac tacaaggttc atttttgaga aaaaattggc tcaggcttta      420

ctggagcaag gaggaaggct gtcttctttc taccaccatg aggcaggtgt cacagctctc      480

agccaggacc cacaaaggat tttgaagcca gctgaaggga acccaactga tcaggctggt      540

ttttctgaag acagagattt tggttacagt gtgggcctga atcctccaga ggaggaagct      600

gtgacatcca agacctgctc ggtgccccct agtgacaccg acacctacag agctggagcg      660

actgcgtcta aggagccgcc cctgtactat ggggtgtgtc cagtgtatga ggacgtccca      720

gcgagaaatg aaaggatcta tgtttatgaa aataaaaagg aagcattgca agctgtcaag      780

atgatcaaag ggtcccgatt taaagctttt tctaccagag aagacgctga gaaatttgct      840

agaggaattt gtgattattt cccttctcca agcaaaacgt ccttaccact gtctcctgtg      900

aaaacagctc cactctttag caatgacagg ttgaaagatg gtttgtgctt gtcggaatca      960

gaaacagtca acaaagagcg agcgaacagt tacaaaaatc cccgcacgca ggacctcacc     1020

gccaagcttc ggaaagctgt ggagaaggga gaggaggaca ccttttctga ccttatctgg     1080

agcaaccccc ggtatctgat aggctcagga gacaacccca ctatcgtgca ggaagggtgc     1140

aggtacaacg tgatgcatgt tgctgccaaa gagaaccagg cttccatctg ccagctgact     1200

ctggacgtcc tggagaaccc tgacttcatg aggctgatgt accctgatga cgacgaggcc     1260

atgctgcaga agcgtatccg ttacgtggtg gacctgtacc tcaacacccc cgacaagatg     1320

ggctatgaca caccgttgca ttttgcttgt aagtttggaa atgcagatgt agtcaacgtg     1380

ctttcgtcac accatttgat tgtaaaaaac tcaaggaata aatatgataa aacacctgaa     1440

gatgtaattt gtgaaagaag caaaaataaa tctgtggaac tgaaggagcg gatcagagag     1500

tatttaaagg gccactacta cgtgcccctc ctgagagcgg aagagacttc ttctccagtc     1560

atcggggagc tgtggtcccc agaccagacg gctgaggcct ctcacgtcag ccgctatgga     1620

ggcagcccca gagacccggt actgaccctg agagccttcg cagggcccct gagtccagcc     1680

aaggcagaag attttcgcaa gctctggaaa actccacctc gagagaaagc aggcttcctt     1740

caccacgtca agaagtcgga cccggaaaga ggctttgaga gagtgggaag ggagctagct     1800

catgagctgg ggtatccctg ggttgaatac tgggaatttc tgggctgttt tgttgatctg     1860

tcttcccagg aaggcctgca aagactagaa gaatatctca cacagcagga aataggcaaa     1920

aaggctcaac aagaaacagg agaacgggaa gcctcctgcc gagataaagc caccacgtct     1980

ggcagcaatt ccatttccgt gagggcgttt ctagatgaag atgacatgag cttggaagaa     2040

ataaaaaatc ggcaaaatgc agctcgaaat aacagcccgc ccacagtcgg tgcttttgga     2100

catacgaggt gcagcgcctt ccccttggag caggaggcag acctcataga agccgccgag     2160

ccgggaggtc cacacagcag cagaaatggg ctctgccatc ctctgaatca cagcaggacc     2220

ctggcgggca agagaccaaa ggccccccgt ggggaggaag cccatctgcc acctgtctcg     2280

gatttgactg ttgagtttga taaactgaat ttgcaaaata taggacgtag cgtttccaag     2340

acaccagatg aaagtacaaa aactaaagat cagatcctga cttcaagaat caatgcagta     2400

gaaagagact tgttagagcc ttctcccgca gaccaactcg ggaatggcca caggaggaca     2460

gaaagtgaaa tgtcagccag gatcgctaaa atgtccttga gtcccagcag ccccaggcac     2520

gaggatcagc tcgaggtcac cagggaaccg gccaggcggc tcttcctttt tggagaggag     2580

ccatcaaaac tcgatcagga tgttttggcc gctcttgaat gtgcagacgt cgacccccat     2640

cagttcccgg ccgtgcacag atggaagagt gctgtcctgt gctactcacc ctcggacaga     2700

cagagttggc ccagtcccgc ggtgaaagga aggttcaagt ctcagctgcc agatctcagt     2760

ggccctcaca gctacagtcc ggggagaaac agcgtggctg gaagcaaccc cgcaaagcca     2820

ggcctgggca gtcctgggcg ctacagcccc gtgcacggga gccagctccg caggatggcg     2880

cgcctggctg agcttgccgc cctgtaggct tggcgctggg ctctcggttt gttcttcatt     2940

tttaaagaag gaagggtcat atgtttattg ctaaactgtc aaaaaggaat atattctgat     3000

taaattatta ctcctcactt tgagggtgtg agaattttag aagatttaaa tgttctatat     3060

aacacttaga tttctgatat tttggaagaa gttagaagtt aatgaaagca aactcagtta     3120

ccaattttct ggaaaatatc catgtggtaa tggtagactt tttaggtggc aatttctagg     3180

tctgaaatat agcagaggaa agggcgctga ggcagttgca ggcaggcagc cctgtactta     3240

ccctgtactc acctcatccg acagacgctg tggatgagga ggggcttggc ggaggcgtga     3300

gcaccgatgt ccctttgata acctgcactc accaagatga actatttgcc gccctgtctt     3360

ttcctgggtt ggggggtggc atctgatggt ggcagagtgc ctgttggttc gcccgtgggt     3420

ctcatggttc agacagaggg aggtggacgg cagggatcag ggagccagga gcgcgcctca     3480

gacttgcagc aaccattgtg atttgggttg ttcggaatat ttaaattact gatcagaaga     3540

tgaaagtagc ttttctcttg ggaagtcttg cagcccgtgg gagtgatacc aggagcaaca     3600

cagagctcag cagcggcgcc aaggtgttcc ctgtttcctc agcacgtgag ccttcaccgc     3660

ctgcttcatt caggagccag tgcagcagta atacagtcta tacattgttc tgttttcaaa     3720

tttatcctga ggctttgttg agcataaatg attatacgat aaaggtatcc gttattttgg     3780

aactcatttc agttgggatc tcctgtatgc agagtgttgc atttagaggt ttgagtccca     3840

tcttggtttc ttgccgtgct gactgtagcc ttcaccttga cttgaatgaa ggtctgtggt     3900

tggaatgtgt gaggagccgc tgaggtgttc aggaggtgct gcctggaggt cggtttcttc     3960

ctgggtgtta cgggcaactg ctcacacagt tgtttctctg tgaacatttc cagtgtttaa     4020

tccaaaatga aaacccacca atgcttttgc taacttcagt gccttttata aatcattttt     4080

aaatttcctg aacttgcttt ttgaggatat acagggatat taagtagacg caggattgtt     4140

tttgtttgta aaaattctga attgaaactt tgttttaaaa aaaggcttct ttctttcata     4200

tgacaagaga taggtcagga atattggaat caagatttaa atgttaaaat tcgattttgt     4260

tacacagggt gtgttcattt gttttgtagc agacaagatc tagatcccag acagaaacaa     4320

cacatgctat tctaaaaagc cgcattttaa aaggcacctt ggttctcaaa agaaatcaga     4380

atatggatat tcgtagtgat gatctgtttt ctctaaaatc ttaccatatt gtctgtatat     4440

ggttgtaaat tcaaatggaa agtaaaacgt tttggccctg ataaaaaaaa aaaaaaaaa      4499


<210>  1024
<211>  1994
<212>  DNA
<213>  homo sapiens

<400>  1024
catattcagc agggttagct tgtcctcccc tccctcttca gcttcccaga cactgagtct       60

ggaatgaaaa ttcacctgcc tctgagttgg ctcctaatgg gggtgggagt gttacttcgg      120

ttcccaggtt ggaagattat ctcacccggc cccagctata taagctgacc ggtgtggagg      180

ggcccagcag ggccaactcc agggattcct tccacgacag aaaaacatac aagactcctt      240

cagccaacat gatggtactg aaagtagagg aactggtcac tggaaagaag aatggcaatg      300

gggaggcagg ggaattcctt cctgaggatt tcagagatgg agagtatgaa gctgctgtta      360

ctttagagaa gcaggaggat ctgaagacac ttctagccca ccctgtgacc ctgggggagc      420

aacagtggaa aagcgagaaa caacgagagg cagagctcaa aaagaaaaaa ctagaacaaa      480

gatcaaagct tgaaaattta gaagaccttg aaataatcat tcaactgaag aaaaggaaaa      540

aatacaggaa aactaaagtt ccagttgtaa aggaaccaga acctgaaatc attacggaac      600

ctgtggatgt gcctacgttt ctgaaggctg ctctggagaa taaactgcca gtagtagaaa      660

aattcttgtc agacaagaac aatccagatg tttgtgatga gtataaacgg acagctcttc      720

atagagcatg cttggaagga catttggcaa ttgtggagaa gttaatggaa gctggagccc      780

agatcgaatt ccgtgatatg cttgaatcca cagccatcca ctgggcaagc cgtggaggaa      840

acctggatgt tttaaaattg ttgctgaata aaggagcaaa aattagcgcc cgagataagt      900

tgctcagcac agcgctgcat gtggcggtga ggactggcca ctatgagtgc gcggagcatc      960

ttatcgcctg tgaggcagac ctcaacgcca aagacagaga aggagatacc ccgttgcatg     1020

atgcggtgag actgaaccgc tataagatga tccgactcct gattatgtat ggcgcggatc     1080

tcaacatcaa gaactgtgct gggaagacgc cgatggatct ggtgctacac tggcagaatg     1140

gaaccaaagc aatattcgac agcctcagag agaactccta caagacctct cgcatagcta     1200

cattctgagg caaacgacag actcttaatc agtaaatgtt cactggcatt ttgaaggcat     1260

ggcccaagag aagagacact agccataaaa tctagtttct atttatcaac gtgttgtgaa     1320

gatgtaccta atgaagtttt gagaaagcac agggttatag gtgtttaaat ttcctttagt     1380

gaaactctta tttattttta tgtattcctg tttatttatt tactgccacg ctactgatat     1440

tcagaccttc atgatcatcc atctggtgag cagagcttca tttgtatata acactttcag     1500

agccttccca cccataggta gttcttaaac caggtgaaag agcaaagttc aagtgcctac     1560

ttatgtgtca ttcgctcatg taagagtttt taagagaggg ctgattatca cagccctctt     1620

ttctcctgaa tttttaatgc agaagtttga atgaagcaag ggaaggcatg tagggacagg     1680

aaaggaaaca atggaaggaa agtgattctg tgaaaaggac agtgaagcca gctattttac     1740

ccccaggctg gatttttttt tttttttttt tttttttttt ttaccgagta cacagagtac     1800

ccaagtgaag agaacgtcat gagtgtaagt gcaaatcagt ggaaggagcg gcaaactggg     1860

acatgcagaa ttgaatttgc tcaaaaaaga tgaaaggaaa tgcaaactgt aaatgtataa     1920

atgtatattg tattgtatgt acattttata ttcataataa aggcaatcaa actcaaaaaa     1980

aaaaaaaaaa aaaa                                                       1994


<210>  1025
<211>  1754
<212>  DNA
<213>  homo sapiens

<400>  1025
agccgccctt tcctctttct ttcgcgctct agccacccgg gaaggcctgc ccagcgtagc       60

tgggctctga ttggctgctt tgaaagtcta cgggctaccc gattggtgaa tccggggccc      120

tttagcgcgg atctaccata cccattgact aactatggaa gattatacca aaatagagaa      180

aattggagaa ggtacctatg gagttgtgta taagggtaga cacaaaacta caggtcaagt      240

ggtagccatg aaaaaaatca gactagaaag tgaagaggaa ggggttccta gtactgcaat      300

tcgggaaatt tctctattaa aggaacttcg tcatccaaat atagtcagtc ttcaggatgt      360

gcttatgcag gattccaggt tatatctcat ctttgagttt ctttccatgg atctgaagaa      420

atacttggat tctatccctc ctggtcagta catggattct tcacttgtta aggtaaaagc      480

ttaactaatt ttattaatat ttatgcactg tggatataaa gggactatat atagaagtcc      540

ctgcattttg tgggaatatg cttggaaaaa gtgttagaat aagaaaaagt atttcatttt      600

tctccctcat ggttagttta tacaggttag agatacccat gttattacca gatagtgttt      660

ctagtaagta aaaattagtg cctgagataa catagaactg gtaggtattg ttggaagcta      720

gggtagtctg gtctttcttt ggctgtcaga tacatgtaaa acaaagtaat gaaagcctag      780

ggcagagtgg tggttgtagg tgttttattc cagttttgaa catgttttgg tcaatttatt      840

gtagacattt attatatttc aggtaaatta taaaattgta tagttttaag tactgaagta      900

tataaaagtg tcttattctt gcaccagttc taccaaacca ctctgcagag gtagcgctgt      960

tagttttatt tgtaatctta cacttgtatg tatgttcact ttgtatgtat ataaagattt     1020

ttttttttac acaaggtgga cttatttgca tatgtatata tacatatttt cccttttttg     1080

tgtaaaacat tatcaagacg tagatctacc tatgtctatt tacatttttg atataattaa     1140

accacttcca tattgatgaa catttaaatt attttccaac ttggttattg ttgctcttat     1200

taacagtact gcactgaatg tccttataga tatttatctt cgtatgcaac tttataggat     1260

aaatttttag aatgggaatg atggattgaa gatgtttatt tacattttga tagatattgc     1320

cggttgcccc ctaaaaaact tgtagcaatt tactcttaaa tactcatggt gtgtaatact     1380

tattgtttta gtacatcatt gccaaaactt ggttttatca atctgttaac tatgtgaaaa     1440

aggcatatta agattgtttt aattttatat ttcatgacaa tttaacactt catatttagc     1500

tattataaac cgcctatatt ttcgttagga tacgttcttt aacaatcttg catgactttt     1560

ggactttctg cttttatgtc ttgcttaagt cttcctcact caaagatcga atgtattaga     1620

ataatacatg tcagtatttt tctggtagtt ttagtaagtc ctgtcttcca cacatacttt     1680

ttttgtctta aattctgtat taagatttat tttgacttaa aaactgggat acagattctg     1740

ctttatcttt ttcc                                                       1754


<210>  1026
<211>  4720
<212>  DNA
<213>  homo sapiens

<400>  1026
gggtcctgga ggcctctggg cgcgtgcgcg ggcggtcgct acctgcggcc gagccaggga       60

gcgagagggc gcagagggca gcgggcttgg gcagcatgag gcccggaggg gagcggcccg      120

tggaaggggg cgcgtgcaat ggccgctccg agctggagct actgaagctg cgctcggcgg      180

agtgcatcga cgaggcggcc gagcggctgg gggccctgag ccgcgcgatc tggagccagc      240

ccgagctggc ctacgaggag caccatgccc accgcgtgct gacgcacttc ttcgagcggg      300

agccgcccgc ggcctcctgg gcagtgcagc cgcactacca gctgcccacg gccttccgcg      360

ccgagtggga gccgccggag gcccgggcac cgagcgccac gccacgcccg ctgcacctgg      420

gcttcctctg cgagtacgac gcgctgcccg gcatcggcca cgcctgcggc cacaacctca      480

tcgctgaggt cggggcggcg gccgcgctgg gcgtgagggg ggccttagag ggcctcccca      540

ggccgcctcc gcccgtgaag gtagttgtcc tgggaacccc tgcagaagaa gatggtggtg      600

gcaaaattga tttaattgaa gcaggggctt ttacaaatct tgatgttgtt tttatggccc      660

acccatcaca agagaatgct gcttatctac cagatatggc tgaacatgat gtgactgtga      720

aatactatgg aaaagcatct cattctgctt cttatccctg ggaaggatta aatgcattag      780

atgctgctgt gctggcctat aacaatctgt ctgtgttcag acagcaaatg aaaccaacct      840

ggagagttca tggtataata aaaaatggtg gtgtaaaacc caatatcatt ccctcttatt      900

ctgaattaat ctattacttc cgtgcaccct caatgaaaga acttcaagtt ttgaccaaaa      960

aggcagaaga ttgcttcaga gctgcagctt tggcttcagg gtgcacagtg gaaattaaag     1020

gtggagcaca tgattattac aatgttcttc ccaataagag cctatggaaa gcctatatgg     1080

aaaatggaag aaagctagga atagagttca tttcagaaga tacaatgttg aatggccctt     1140

caggatctac ggattttgga aatgttagtt ttgtggttcc tggaattcat ccatattttc     1200

acattggatc taatgccttg aatcatactg aacagtacac tgaagctgct gggtcacagg     1260

aagctcagtt ctacactctg cggacggcca aagctctggc aatgacggca ctggatgtta     1320

tttttaaacc agagttactg gaaggaatca gagaggactt taaactgaaa cttcaagaag     1380

aacagtttgt aaatgcagta gaataaaaga cttaggggcc acttataaat caagaagacg     1440

tgatgatttt tttcttttaa tctcttttaa tgaaggcatg cttgtttttt aatcttaaag     1500

gagtaaaatt ctttttacct gataagtgag gacagggtgt ggagaaaaca tattaattac     1560

ctcatatcta aagtgaaaat ttttgcaaat ccgtacttga taggattatg atattacagg     1620

agctggtatg tgatgccatt ctttcttttt ttttaccccg caaccactca ccttcacagt     1680

agtgatacca tttcttaacc tggaggatac atggcatcat ttttataaaa tatgttagta     1740

aacctttttg taagccttaa atgttatgtg tatttttaaa agcttaagag atttcaaacc     1800

ttatattcag aattgacacc catgagagtg ttttgtggta tagggtggta aacttgttct     1860

ctaatcgtat attaattcct ctaccagatt gtatatttga agccagtgtc tttccttttt     1920

ttgttttaag atagagcctc gctctgttgc ccaggctgaa gtgtagtggc acaatctcgg     1980

ctcactgcaa cctctgcctc ccaggttcaa gtgattctcc tgcctcagcc taccaagtag     2040

ctgggattac aggtgtgtgg caccatgccc agctaatttt tgtattttta gtagagacgg     2100

catttcacca tgttggccag gctggtctcg aactcctgac ctcaggtgat gcacctgcct     2160

cggcctccta aagtgctggg attacaggca tgagccaccg cacccggcct gccagtgtct     2220

ttttaataca catgtgtgtt ggtattttta aattgttaca gtatctagca tattgcttac     2280

tctgaatatt cagtactttt tgaataagca aatattgctt ccttgcttgg aatcatcaga     2340

gtttaaagta gcttcgtgga tggaccatga tcctaagatg agttttaatt ttgtgtttac     2400

agtcatctct tgtacaacgt ggagaagaaa agatatactt actactttgc ttcaggtaca     2460

cataagaaaa cctctttttt aaaaaaattt ttattttttt acataataga gacaggggct     2520

cgctgtagct tccaggctgg cctcaaactc ctgggctcaa gcaatcctcc tgtcttggcc     2580

tcccaaagtg ttgggatttc aggtatgaga caccacacct gcccattttt gtttggtttt     2640

ttaatgggca ggttcttgct ctcccaggct ggagtgcagt ggtgtaatca cagctcactg     2700

cagtctcgaa ctcctggact caagcagtcc tcccacctca gcctcctaaa gcactgggat     2760

tacaggcttg aggcactgca cctggccctg accatttttt aaaaaggtta ggcttagtgc     2820

aaagtttaaa attatatgat tcttaaaata ctgaattagt ttctaaacta aactagaggt     2880

ataggtggac ctgcttgagg tatctttgtt tttatggaac atttttatta catgccttta     2940

taatttttca ttgttcacac cctgtactga aacctttttc tcaaatacca actcttggct     3000

atgttaaatt tgtagacttt aaaagatgtt atctaaatta atggtttaaa tatacaaatt     3060

gaaaatattt tctttttagt ggcaatttta aaagcaggcc ttaatatggg acctgctttt     3120

aaagtaaaat atgtggtact atgaattact aaattgctat ataccatgta atagtgagta     3180

tagctaatat ttagtatgcc ttttaaaaat tttggactgc ttttcggttt taacaaattc     3240

tccacatgtg aactactcaa gaaattttcc ctttttaatt gcctctatag cactcataag     3300

agctagggca ttaggataaa ctagaatatt ttatgtttat gaatacttgt ataaacttaa     3360

aagtgttttg atttcccaca atttcccaaa ggaatgttta tttattaaga gttgtgttga     3420

taatttaact gttacaattt cagcagttga attcagtgaa cactggttga ggagtgccta     3480

tttctaagca ctgggtgtaa gaagaaaaga cacttgcaaa ggaagagcta agattaacat     3540

aatttctttg gtttttctat tgcttgttat tattatgtaa aaactgggtg gcagttcaca     3600

aggaagattg ttgtaacaga agagtgacaa ccaatagttt tttgatcatt aaatcaaatt     3660

ttgtaaacag tggcaggagc gtggacttaa aacaaggctt gcttatttgg ttttgtcaaa     3720

gttttacgaa aatatatgat atatatttat actaaaacta tataatcctt agatttagga     3780

aagcaatcag ttaatgtctt tagcacacta aagcagtatt aaacacaggt acaagttgga     3840

aattgtagaa aactgaaaga aaacaagaca aaatgtctat ggtagggaat aaaagagttt     3900

aagatattat gtaaaattat gtgtattttc ttctctttta cataaattgt ttgtgaaaag     3960

tgtgctcaac ttttttacaa gagtgatatt aacttggatt tatttttcaa tataatttgg     4020

agaccctttg ttatccaaat aaaattgatg agtttctgtg cctgtaaaaa aaaaaaaaaa     4080

aaaaagaaaa gaaaagacac tgttgcatgc cccagaaagc ttgtggtggg tggtaagttc     4140

tcacgagatt tatttatctg agcaacattg ggactgaggg aacatctgaa agctaccatc     4200

ttgaaaattt ttgaggaagt gtttctgaaa tatttaaaaa tacttaagtc agtcattttg     4260

aacaaaagaa attgatacaa taagtttttt tttttaagga tgattgtcta attttgtaat     4320

atgttgtttt ttaaaaacct gtctgatggt gttttataca tttctaactt tttacctgag     4380

ttatctcttt agtcttttgg aaaataccct acacaatact aacctttaaa actatcaaat     4440

ttttgttata agataaatgt tatctttgta ctagatagca accctttata aggttgtaag     4500

gtataataaa ctgcttattt ttttacatac ttcatatcaa gcattttgca gtccaattat     4560

atagttgagg atggtgtatt ttgatatgta tgaagttaat attttcaagt aagcaatcag     4620

tctactacca tcagattata agcttttttg taataatagg tacataaaat gtgtatgaaa     4680

aatctacaat aaacatgttt atctgatagc aaaaaaaaaa                           4720


<210>  1027
<211>  4108
<212>  DNA
<213>  homo sapiens

<400>  1027
agtaatagca ggagcagcaa cagaaggcgt cggagcgggc gtcggagctg cccgctgtgg       60

gagagagagg agacagaaag agcgagcgag gagagggagc ccgaggcgaa aaagtaactg      120

tcaaatgcgc ggctccttta accggagcgc tcagtccggc tccgagagtc atggcgaccg      180

cagcgtctaa ccactacagc ctgctcacct ccagcgcctc catcgtgcac gccgagccgc      240

ccggcggcat gcagcagggc gcggggggct accgcgaagc gcagagcctg gtgcagggcg      300

actacggcgc tctgcagagc aacggacacc cgctcagcca cgctcaccag tggatcaccg      360

cgctgtccca cggcggcggc ggcgggggcg gtggcggcgg cggggggggc gggggcggcg      420

gcgggggcgg cggcgacggc tccccgtggt ccaccagccc cctgggccag ccggacatca      480

agccctcggt ggtggtgcag cagggcggcc gcggagacga gctgcacggg ccaggcgccc      540

tgcagcagca gcatcagcag cagcaacagc aacagcagca gcaacagcag caacagcagc      600

agcagcagca gcaacagcgg ccgccgcatc tggtgcacca cgccgctaac caccacccgg      660

gacccggggc atggcggagc gcggcggctg cagcgcacct cccaccctcc atgggagcgt      720

ccaacggcgg cttgctctac tcgcagccca gcttcacggt gaacggcatg ctgggcgccg      780

gcgggcagcc ggccggtctg caccaccacg gcctgcggga cgcgcacgac gagccacacc      840

atgccgacca ccacccgcac ccgcactcgc acccacacca gcagccgccg cccccgccgc      900

ccccgcaggg tccgcctggc cacccaggcg cgcaccacga cccgcactcg gacgaggaca      960

cgccgacctc ggacgacctg gagcagttcg ccaagcagtt caagcagcgg cggatcaaac     1020

tgggatttac ccaagcggac gtggggctgg ctctgggcac cctgtatggc aacgtgttct     1080

cgcagaccac catctgcagg tttgaggccc tgcagctgag cttcaagaac atgtgcaagc     1140

tgaagccttt gttgaacaag tggttggagg aggcggactc gtcctcgggc agccccacga     1200

gcatagacaa gatcgcagcg caagggcgca agcggaaaaa gcggacctcc atcgaggtga     1260

gcgtcaaggg ggctctggag agccatttcc tcaaatgccc caagccctcg gcccaggaga     1320

tcacctccct cgcggacagc ttacagctgg agaaggaggt ggtgagagtt tggttttgta     1380

acaggagaca gaaagagaaa aggatgaccc ctcccggagg gactctgccg ggcgccgagg     1440

atgtgtacgg ggggagtagg gacactccac cacaccacgg ggtgcagacg cccgtccagt     1500

gaactcgagc tgggggaggg gcagagcgcg gggctccccc tccccttcgg tccttggccc     1560

tttcccggcc ctcttgttcc ctctctaact tctgattgtt cttttatttt taattattat     1620

ttccccgtcc cttaaaaaga caaaaaaaat aaggcaaaag gaaagcaact aagacactgg     1680

actatccttt aaaggtagca ggtgtaatga tgtgttttga cctttgcagg cgagtaacca     1740

ggcaatggag tggagtgtct cctggagaga gtgaggagag tgtgtgatag ctagaaagag     1800

agagagacag agagatggca agcactgaga taaatacctg gcaaaactaa ataaattacc     1860

aaaaaggaaa aaaaatccac caaaccatga taaacacaaa atgcagcttc ctgatgctta     1920

gagttggcac atgctgctgt gtttatttat tgtggattcc catcaggaaa gaggaaaaaa     1980

tacacatgtt ctttcatata ggcaaaattt aaccacataa atttgcactg caagaaaatt     2040

gaagtttacg tgaacaaatt catgagcata ttttctcttt ctccccaccg ttaatttggg     2100

agttgccgtt ttgggggatt ttgttttgct ttgctttatt catcggagag agttgaagcc     2160

agctcttggc cactctccat ttctaatgtt cttgtgttgc cccttcttcg tactgtttgt     2220

gaactttggt taccttcaca ttccccttac gagggtgtaa catctatttg ttcctcttac     2280

caaagcaaaa ggattggctt catacaaaat agacaattct ctgatttcag gaaatgtgca     2340

tggtctaccc gctttatcga aggcaagaat ccggtttgga atataaaaat aagcattggt     2400

tgttcttacc agccacaaag taaacttcat tttcaggcag tgtttctggg ggaggttatg     2460

gagggaagaa aaaagaaaaa tcgatagtga gtgactgatt gcttcatttt atcaggcggg     2520

cccattgtga aagagctcag gggaaatgtg gaggttaaat atatttccag agttgtccag     2580

cagaaagaaa gtggcacttt gaagagaact agggaagtac atatcttcag atatccctat     2640

atagttctct accttcagtt ttagtaacaa ttatgaagaa ttatttgtgc tgacagcagc     2700

agttaaactt tgtttctcta atagcttttt ttttacataa aaaaagaccc aggaacttaa     2760

tagtgtatgc ataagactgt gttttttagc acacagatac ccacagcata cactgacgat     2820

ctccacgcag tagacaggtt ttgtcttcac tagctcattt gtttatcaag tcatatttag     2880

ggtcccacac cctcttttcc tgtaatttat tgcagaatac accactttga cttggacagc     2940

tttctgcccc ctctttcact aaggaaggca aatgaagtga aaaaaaaaaa tgccattttc     3000

aatccttcct ttctcccctt tgttaatagt tttaagtgaa tttttgacct tatcttaatg     3060

gaaaacggtt aactccaaac acaaaagact ctactggaaa gtgtaggtga aaaaacttgt     3120

aactgtattg aaaataaata ccattaaact gtgatcagtt aaaatttaaa agaaaaatca     3180

gcacaaaagg gcgctaaaag ggaaaacact ttttattaat cttaaaagtt tgggggtttt     3240

tttccagtta ggtattagat aaatttttat tttaaaaaat gaaagtctca ctaccataaa     3300

attatggttc agcatcagat tagcattgca ctcagtagtc tttaaggttt taggaaatat     3360

gctttatatt gtcttttcaa acacctgtga ttgtttcatt ttccatgttt ttgcaagata     3420

aatggtgact tataatgggc atatttattt gcctgtattt catttccccc aatgaatgtc     3480

acaaggagat gggcacggag ctgcttcggg tgcatcacgc tgctcgttcc tgaggtatgg     3540

gaactggcct ttagtgaagc tatccagagc agggcaaata gccactggta aagggaggaa     3600

atgaatttcc agatacttat taccaagtag gtaaggtcag aagctggagt tcagagaatg     3660

tgtctacagc ttctctgact cttataggtt tactaagatg aaagttacca ctgaacctta     3720

ccactatgta tatatgttta atatctgtct tttgaaatgc agaaatagtt taaatgtttc     3780

tttgtctatt tttctttttt tttaatgcta cccagggaaa tattttcata tcatttttaa     3840

gtggcctgcc tcaatgtata tttatttctt ttgaaacaaa aaggttctgg aaactgtttt     3900

tctgtagctt taaatgaata ggtgagcaaa atctatatgg gatgtaattt ttttgttcag     3960

tctcttaaaa aatactttgt tttggtacat ttggttgtgc ttgtggggaa aataaaaacg     4020

cagagatcct tatatattta tgttaaagta atattttatt atctacataa aacagaaatg     4080

cacaataaaa aaaaaaaaaa aaaaaaaa                                        4108


<210>  1028
<211>  1517
<212>  DNA
<213>  homo sapiens

<400>  1028
gcgaggcagg agccggcggc tgggctccgc agcgcagcca gcgcagcgcg gcgccccggg       60

cccggcccca tgcccgcagc cccgccggac cgtccttgag cgcgggcgcc tagcccgcgc      120

cccctgcccg ccggcaccat tgccccgacg gcgcggccgg gcggcccggc gctccccagg      180

ctccgcgcgg gccgaaagac gctgctagcg gccgccgcgg gtgtggtgat gctgctggtg      240

ctggtggtgc tcatccccgt gctggtgagc tcgggcggcc cggaaggcca ctatgagatg      300

ctgggcacct gccgcatggt gtgcgacccc taccccgcgc ggggccccgg cgccggcgcg      360

cggaccgacg gcggcgacgc cctgagcgag cagagcggcg cgcccccgcc ttccacgctg      420

gtgcagggcc cccaggggaa gccgggccgc accggcaagc ccggccctcc ggggcctccc      480

ggggacccag gtcctcccgg ccctgtgggg ccgccggggg agaagggtga gccaggcaag      540

ccgggccctc cggggctgcc gggcgcgggg ggcagcggcg ccatcagcac tgccacctac      600

accacggtgc cgcgcgtggc cttctacgcc ggcctcaaga acccccacga gggttacgag      660

gtactcaagt ttgacgacgt ggtcaccaac ctaggcaaca actacgacgc ggccagcggc      720

aagtttacgt gcaacattcc cggcacctac tttttcacct accatgtcct catgcgcggc      780

ggcgacggca ccagtatgtg ggcagacctc tgcaagaatg gccaggtgcg ggccagtgct      840

attgcccagg acgcggacca gaactacgac tacgccagca acagcgtgat cctgcacctg      900

gacgccggcg acgaggtctt catcaagctg gatggaggca aagcacacgg cggcaacagc      960

aacaaataca gcacgttctc tggcttcatc atctactccg actgagctcc ccacgtctcc     1020

ctccacccac gtccctcacc cgccggggtc ccctccgggc ggggcagacg atgactcgcc     1080

cctcgcccac ccgctcgctg cccggccctc cccggctatg acgcccccgg cccgtgctca     1140

acaccgcctg ggccacagct aggccctccc accggctcgc tgcagagccg ggcccagcgc     1200

gccctgtccc cgtgccaggg aaccggggtt gaccgccccc gcccagcccg cgctatatat     1260

ttgtacaata ggactgttta ctgcccacct ccgcctgcca gcccacccca gcctggggag     1320

aggtcgcggc ggcgggtttg cttcctgcgc tctgagatga gctgccctcc gctccctccg     1380

gggtggcgcg cccgggggag gggggagttg ggggctggat agcttcccag caccctcaga     1440

gcccccgccc ggctgtgccc cgtctgacca aagttataat aaaaacattt tcaccccgca     1500

aaaaaaaaaa aaaaaaa                                                    1517


<210>  1029
<211>  1517
<212>  DNA
<213>  homo sapiens

<400>  1029
gcgaggcagg agccggcggc tgggctccgc agcgcagcca gcgcagcgcg gcgccccggg       60

cccggcccca tgcccgcagc cccgccggac cgtccttgag cgcgggcgcc tagcccgcgc      120

cccctgcccg ccggcaccat tgccccgacg gcgcggccgg gcggcccggc gctccccagg      180

ctccgcgcgg gccgaaagac gctgctagcg gccgccgcgg gtgtggtgat gctgctggtg      240

ctggtggtgc tcatccccgt gctggtgagc tcgggcggcc cggaaggcca ctatgagatg      300

ctgggcacct gccgcatggt gtgcgacccc taccccgcgc ggggccccgg cgccggcgcg      360

cggaccgacg gcggcgacgc cctgagcgag cagagcggcg cgcccccgcc ttccacgctg      420

gtgcagggcc cccaggggaa gccgggccgc accggcaagc ccggccctcc ggggcctccc      480

ggggacccag gtcctcccgg ccctgtgggg ccgccggggg agaagggtga gccaggcaag      540

ccgggccctc cggggctgcc gggcgcgggg ggcagcggcg ccatcagcac tgccacctac      600

accacggtgc cgcgcgtggc cttctacgcc ggcctcaaga acccccacga gggttacgag      660

gtactcaagt ttgacgacgt ggtcaccaac ctaggcaaca actacgacgc ggccagcggc      720

aagtttacgt gcaacattcc cggcacctac tttttcacct accatgtcct catgcgcggc      780

ggcgacggca ccagtatgtg ggcagacctc tgcaagaatg gccaggtgcg ggccagtgct      840

attgcccagg acgcggacca gaactacgac tacgccagca acagcgtgat cctgcacctg      900

gacgccggcg acgaggtctt catcaagctg gatggaggca aagcacacgg cggcaacagc      960

aacaaataca gcacgttctc tggcttcatc atctactccg actgagctcc ccacgtctcc     1020

ctccacccac gtccctcacc cgccggggtc ccctccgggc ggggcagacg atgactcgcc     1080

cctcgcccac ccgctcgctg cccggccctc cccggctatg acgcccccgg cccgtgctca     1140

acaccgcctg ggccacagct aggccctccc accggctcgc tgcagagccg ggcccagcgc     1200

gccctgtccc cgtgccaggg aaccggggtt gaccgccccc gcccagcccg cgctatatat     1260

ttgtacaata ggactgttta ctgcccacct ccgcctgcca gcccacccca gcctggggag     1320

aggtcgcggc ggcgggtttg cttcctgcgc tctgagatga gctgccctcc gctccctccg     1380

gggtggcgcg cccgggggag gggggagttg ggggctggat agcttcccag caccctcaga     1440

gcccccgccc ggctgtgccc cgtctgacca aagttataat aaaaacattt tcaccccgca     1500

aaaaaaaaaa aaaaaaa                                                    1517


<210>  1030
<211>  7592
<212>  DNA
<213>  homo sapiens

<400>  1030
gcggccgcgg ccggaggagc aatagcagca gccgtggcgg ccacggggcg gggcgcggcg       60

gtcggtgacc gcggccgggg ctgcaggcgg cggagcggct ggaagttgga ttccatgggt      120

tccaagagaa gaagagctac ctccccttcc agcagtgtca gcggggactt tgatgatggg      180

caccattctg tgtcaacacc aggcccaagc aggaaaagga ggagactttc caatcttcca      240

actgtagatc ctattgccgt gtgccatgaa ctctataata ccatccgaga ctataaggat      300

gaacagggca gacttctctg tgagctcttc attagggcac caaagcgaag aaatcaacca      360

gactattatg aagtggtttc tcagcccatt gacttgatga aaatccaaca gaaactaaaa      420

atggaagagt atgatgatgt taatttgctg actgctgact tccagcttct ttttaacaat      480

gcaaagtcct attataagcc agattctcct gaatataaag ccgcttgcaa actctgggat      540

ttgtaccttc gaacaagaaa tgagtttgtt cagaaaggag aagcagatga cgaagatgat      600

gatgaagatg ggcaagacaa tcagggcaca gtgactgaag gatcttctcc agcttacttg      660

aaggagatcc tggagcagct tcttgaagcc atagttgtag ctacaaatcc atcaggacgt      720

ctcattagcg aactttttca gaaactgcct tctaaagtgc aatatccaga ttattatgca      780

ataattaagg agcctataga tctcaagacc attgcccaga ggatacagaa tggaagctac      840

aaaagtattc atgcaatggc caaagatata gatctcctcg caaaaaatgc caaaacttat      900

aatgagcctg gctctcaagt attcaaggat gcaaattcaa ttaaaaaaat attttatatg      960

aaaaaggctg aaattgaaca tcatgaaatg gctaagtcaa gtcttcgaat gaggactcca     1020

tccaacttgg ctgcagccag actgacaggt ccttcacaca gtaaaggcag ccttggtgaa     1080

gagagaaatc ccactagcaa gtattaccgt aataaaagag cagtacaagg aggtcgttta     1140

tcagcaatta caatggcact tcaatatggc tcagaaagtg aagaagatgc tgctttagct     1200

gctgcacgct atgaagaggg agagtcagaa gcagaaagca tcacttcctt tatggatgtt     1260

tcaaatcctt tttatcagct ttatgacaca gttaggagtt gtcggaataa ccaagggcag     1320

ctaatagctg aaccttttta ccatttgcct tcaaagaaaa aataccctga ttattaccag     1380

caaattaaaa tgcccatatc actacaacag atccgaacaa aactgaagaa tcaagaatat     1440

gaaactttag atcatttgga gtgtgatctg aatttaatgt ttgaaaatgc caaacgctat     1500

aatgtgccca attcagccat ctacaagcga gttctaaaat tgcagcaagt tatgcaggca     1560

aagaagaaag agcttgccag gagagacgat atcgaggacg gagacagcat gatctcttca     1620

gccacctctg atactggtag tgccaaaaga aaaagtaaaa agaacataag aaagcagcga     1680

atgaaaatct tattcaatgt tgttcttgaa gctcgagagc caggttcagg cagaagactt     1740

tgtgacctat ttatggttaa accatccaaa aaggactatc ctgattatta taaaatcatc     1800

ttggagccaa tggacttgaa aataattgag cataacatcc gcaatgacaa atatgctggt     1860

gaagagggaa tgatagaaga catgaagctg atgttccgga atgccaggca ctataatgag     1920

gagggctccc aggtttataa tgatgcacat atcctggaga agttactcaa ggagaaaagg     1980

aaagagctgg gcccactgcc tgatgatgat gacatggctt ctcccaaact caagctgagt     2040

aggaagagtg gcatttctcc taaaaaatca aaatacatga ctccaatgca gcagaaacta     2100

aatgaggtct atgaagctgt aaagaactat actgataaga ggggtcgccg cctcagtgcc     2160

atatttctga ggcttccctc tagatctgag ttgcctgact actatctgac tattaaaaag     2220

cccatggaca tggaaaaaat tcgaagtcac atgatggcca acaagtacca agatattgac     2280

tctatggttg aggactttgt catgatgttt aataatgcct gtacatacaa tgagccggag     2340

tctttgatct acaaagatgc tcttgttcta cacaaagtcc tgcttgaaac acgcagagac     2400

ctggagggag atgaggactc tcatgtccca aatgtgactt tgctgattca agagcttatc     2460

cacaatcttt ttgtgtcagt catgagtcat caggatgatg agggaagatg ctacagcgat     2520

tctttagcag aaattcctgc tgtggatccc aactttccta acaaaccacc ccttacattt     2580

gacataatta ggaagaatgt tgaaaataat cgctaccgtc ggcttgattt atttcaagag     2640

catatgtttg aagtattgga acgagcaaga aggatgaatc ggacagattc agaaatatat     2700

gaagatgcag tagaacttca gcagtttttt attaaaattc gtgatgaact ctgcaaaaat     2760

ggagagattc ttctttcacc ggcactcagc tataccacaa aacatttgca taatgatgtg     2820

gagaaagaga gaaaggaaaa attgccaaaa gaaatagagg aagataaact aaaacgagaa     2880

gaagaaaaaa gagaagctga aaagagtgaa gattcctctg gtgctgcagg cctctcaggc     2940

ttacatcgca catacagcca ggactgtagc tttaaaaaca gcatgtacca tgttggagat     3000

tacgtctatg tggaacctgc agaggccaac ctacaaccac atatcgtctg tattgaaaga     3060

ctgtgggagg attcagctga aaaagaagtt tttaagagtg actattacaa caaagttcca     3120

gttagtaaaa ttctaggcaa gtgtgtggtc atgtttgtca aggaatactt taagttatgc     3180

ccagaaaact tccgagatga ggatgttttt gtctgtgaat cacggtattc tgccaaaacc     3240

aaatctttta agaaaattaa actgtggacc atgcccatca gctcagtcag gtttgtccct     3300

cgggatgtgc ctctgcctgt ggttcgcgtg gcctctgtat ttgcaaatgc agataaaggt     3360

gatgatgaga agaatacaga caactcagag gacagtcgag ctgaagacaa ttttaacttg     3420

gaaaaggaaa aagaagatgt ccctgtggaa atgtccaatg gtgaaccagg ttgccactac     3480

tttgagcagc tccattacaa tgacatgtgg ctgaaggttg gcgactgtgt cttcatcaag     3540

tcccatggcc tggtgcgtcc tcgtgtgggc agaattgaaa aagtatgggt tcgagatgga     3600

gctgcatatt tttatggccc catcttcatt cacccagaag aaacagagca tgagcccaca     3660

aaaatgttct acaaaaaaga agtatttctg agtaatctgg aagaaacctg ccccatgaca     3720

tgtattctcg gaaagtgtgc tgtgttgtca ttcaaggact tcctctcctg caggccaact     3780

gaaataccag aaaatgacat tctgctttgt gagagccgct acaatgagag cgacaagcag     3840

atgaagaaat tcaaaggatt gaagaggttt tcactctctg ctaaagtggt agatgatgaa     3900

atttactact tcagaaaacc aattgttcct cagaaggagc catcaccttt gctggaaaag     3960

aagatccagt tgctagaagc taaatttgcc gagttagaag gtggagatga tgatattgaa     4020

gagatgggag aagaagatag tgagtctacc ccaaagtctg ccaaaggcag tgcaaagaag     4080

gaaggctcca aacggaaaat caacatgagt ggctacatcc tgttcagcag tgagatgagg     4140

gctgtgatta aggcccaaca cccagactac tctttcgggg agctcagccg cctggtgggg     4200

acagaatgga gaaatcttga gacagccaag aaagcagaat atgaaggcat gatgggtggc     4260

tatccgccag gccttccacc tttgcagggc ccagttgatg gccttgttag catgggcagc     4320

atgcagccac ttcaccctgg ggggcctcca ccccaccatc ttccgccagg tgtgcctggc     4380

ctcccgggca tcccaccacc gggtgtgatg aaccaaggag tggcccctat ggtagggact     4440

ccagcaccag gtggaagtcc atatggacaa caggtgggag ttttggggcc tccagggcag     4500

caggcaccac ctccatatcc cggcccacat ccagctggac cccctgtcat acagcagcca     4560

acaacaccca tgtttgtagc tcccccacca aagacccagc ggcttcttca ctcagaggcc     4620

tacctgaaat acattgaagg actcagtgcg gagtccaaca gcattagcaa gtgggatcag     4680

acactggcag ctcgaagacg cgacgtccat ttgtcgaaag aacaggagag ccgcctaccc     4740

tctcactggc tgaaaagcaa aggggcccac accaccatgg cagatgccct ctggcgcctt     4800

cgagatttga tgctccggga caccctcaac attcgccaag catacaacct agaaaatgtt     4860

taatcacatc attacgtttc ttttatatag aagcataaag agttgtggat cagtagccat     4920

tttagttact gggggtgggg ggaaggaaca aaggaggata atttttattg cattttactg     4980

tacatcacaa ggccattttt atatacggac acttttaata agctatttca atttgtttgt     5040

tatattaagt tgactttatc aaatacacaa agattttttt gcatatgttt ccttcgttta     5100

aaaccagttt cataattggt tgtatatgta gacttggagt tttatctttt tacttgttgc     5160

catggaactg aaaccattag aggtttttgt cttggcttgg ggtttttgtt ttcttggttt     5220

tgggtttttt tatatatata tataaaagaa caaaatgaaa aaaaacacac acacacaaga     5280

gtttacagat tagtttaaat tgataatgaa atgtgaagtt tgtcctagtt tacatcttag     5340

agaggggagt atacttgtgt ttgtttcatg tgcctgaata tcttaagcca ctttctgcaa     5400

aagctgtttc ttacagatga agtgctttct ttgaaaggtg gttatttagg ttttagatgt     5460

ttaatagaca cagcacattt gctctattaa ctcagaggct cactacagaa atatgtaatc     5520

agtgctgtgc atctgtctgc agctaatgta cctcctggac accaggaggg gaaaaagcac     5580

tttttcaatt gtgctgagtt agacatctgt gagttagact atggtgtcag tgatttttgc     5640

agaacacgtg cacaaccctg aggtatgttt aatctaggca ggtacgttta aggatatttt     5700

gatctattta taatgaattc acaatttatg cctataaatt tcagatgatt taaaatttta     5760

aacctgttac attgaaaaac attgaagttc gtcttgaaga aagcattaag gtatgcatgg     5820

aggtgattta tttttaaaca taacacctaa cctaacatgg gtaagagagt atggaactag     5880

atatgagctg tataagaagc ataattgtga acaagtagat tgattgcctt catatacaag     5940

tatgttttag tattccttat ttccttatta tcagatgtat tttttctttt aagtttcaat     6000

gttgttataa ttctcaacca gaaatttaat actttctaaa atatttttta aatttagctt     6060

gtgcttttga attacaggag aagggaatca taatttaata aaacgcttac tagaaagacc     6120

attacagatc ccaaacactt gggtttggtg accctgtctt tcttatatga ccctacaata     6180

aacatttgaa ggcagcatag gatggcagac agtaggaaca ttgtttcact tggcggcatg     6240

tttttgaaac ctgctttata gtaactgggt gattgccatt gtggtagagc ttccactgct     6300

gtttataatc tgagagagtt aatctcagag gatgcttttt tccttttaat ctgctatgaa     6360

tcagtaccca gatgtttaat tactgtactt attaaatcat gagggcaaaa gagtgtagaa     6420

tggaaaaaag tctcttgtat ctagatactt taaatatggg aggcccttta acttaattgc     6480

ctttagtcaa ccactggatt tgaatttgca tcaagtattt taaataatat tgaatttaaa     6540

aaaatgtatt gcagtagtgt gtcagtacct tattgttaaa gtgagtcaga taaatcttca     6600

attcctggct atttgggcaa ttgaatcatc atggactgta taatgcaatc agattatttt     6660

gtttctagac atccttgaat tacaccaaag aacatgaaat ttagttgtgg ttaaattatt     6720

tatttatttc atgcattcat tttatttccc ttaaggtctg gatgagactt ctttggggag     6780

cctctaaaaa aatttttcac tgggggccac gtgggtcatt agaagccaga gctctcctcc     6840

aggctccttc ccagtgccta gaggtgctat aggaaacata gatccagcca ggggcttccc     6900

taaagcagtg cagcaccggc ccagggcatc actagacagg ccctaattaa gtttttttta     6960

aaaagcctgt gtatttattt tagaatcatg tttttctgta tattaacttg ggggatatcg     7020

ttaatattta ggatataaga tttgaggtca gccatcttca aaaaagaaaa aaaaattgac     7080

tcaagaaagt acaagtaaac tatacacctt tttttcataa gttttaggaa ctgtagtaat     7140

gtggcttaga aagtataatg gcctaaatgt tttcaaaatg taagttcctg tggagaagaa     7200

ttgtttatat tgcaaacggg gggactgagg ggaacctgta ggtttaaaac agtatgtttg     7260

tcagccaact gatttaaaag gcctttaact gttttggttg ttgttttttt tttaagccac     7320

tctccccttc ctatgaggaa gaattgagag gggcacctat ttctgtaaaa tccccaaatt     7380

ggtgttgatg attttgagct tgaatgtttt catacctgat taaaacttgg tttattctaa     7440

tttctgtatc atatcatctg aggtttacgt ggtaactagt cttataacat gtatgtatct     7500

tttttttgtt gttcatctaa agctttttaa tccaaataaa tacagagttt gcaaagtgat     7560

ttggattaac caggaaaaaa aaaaaaaaaa aa                                   7592


<210>  1031
<211>  7420
<212>  DNA
<213>  homo sapiens

<400>  1031
ctctgcgctg cccggtgggg cggggaaaga agccctgagc cgggatctgg cactcccagg       60

actcccggcc ggggtagctc ttcactcctc agcgcgacgt cgtgtcgagt tcccaaaaag      120

ctccgcaggg gctgtaggga ggtgatctca tccattaaca gctgtgtgtt gccagttccc      180

aaatctttat ctatctcaga cttctctcct gcattccaga ttcttatatt cagctgcctt      240

ttggatatct ctcccaggat gttctcaagg catacaagaa ttaaattctg aataagtctg      300

caggtaggat ggacagttat tttaaagcag ctgtcagtga cttggacaaa ctccttgatg      360

attttgaaca gaacccagat gaacaagatt atctccaaga tgtacaaaat gcatatgatt      420

ctaaccactg ctcagtttct tcagagttgg cttcctcaca gcgaacttca ttgctcccaa      480

aagaccaaga gtgcgttaat agttgtgcct catcagaaac aagctatgga acaaatgaga      540

gttccctgaa tgaaaaaaca ctcaagggac ttacttctat acaaaatgaa aaaaatgtaa      600

caggacttga tcttctttct tctgtggatg gtggtacttc agatgaaatc cagccgttat      660

atatgggacg atgtagtaaa cctatctgtg atctgataag tgacatgggt aacttagttc      720

atgcaaccaa tagtgaagaa gatattaaaa aattattgcc agatgatttt aagtctaatg      780

cagattcctt gattggattg gatttatctt cagtgtcaga tactccctgt gtttcttcaa      840

cagaccatga tagtgatact gtcagagaac aacagaatga tatcagttct gaattacaaa      900

atagagaaat cggaggaatc aaagaattgg gtataaaagt agatacaaca ctttcagatt      960

cctataatta cagtggaaca gaaaatttaa aagataaaaa gatctttaat cagttagaat     1020

caattgttga ttttaacatg tcatctgctt tgactcgaca aagttccaaa atgtttcatg     1080

ccaaagacaa gctacaacac aagagccagc catgtggatt actaaaagat gttggcttag     1140

taaaagagga agtagatgtg gcagtcataa ctgccgcaga atgtttaaaa gaagagggca     1200

agacaagtgc tttgacctgc agccttccga aaaatgaaga tttatgctta aatgattcaa     1260

attcaagaga tgaaaatttc aaattacctg acttttcctt tcaggaagat aagactgtta     1320

taaaacaatc tgcacaagaa gactcaaaaa gtttagacct taaggataat gatgtaatcc     1380

aagattcctc ttcagcttta catgtttcca gtaaagatgt gccgtcctca ttgtcctgtc     1440

ttcctgcgtc tgggtctatg tgtggatcat taattgaaag taaagcacgg ggtgattttt     1500

tacctcagca tgaacataaa gataatatac aagatgcagt gactatacat gaagaaatac     1560

agaacagtgt tgttctaggt ggggaaccat tcaaagagaa tgatcttttg aaacaggaaa     1620

aatgtaaaag catactcctt cagtcattaa ttgaagggat ggaagacaga aagatagatc     1680

ctgaccagac agtaatcaga gctgagtctt tggatggtgg tgacaccagt tctacagttg     1740

tagaatctca agaggggctt tctggcactc atgtcccaga gtcttctgat tgttgtgaag     1800

gttttattaa tactttttca agcaatgata tggatgggca agacttagat tactttaata     1860

ttgatgaagg cgcaaaaagt ggcccactaa ttagtgatgc tgaacttgat gcctttctga     1920

cagaacagta tcttcagacc actaacataa agtcttttga agaaaatgta aatgactcta     1980

aatcgcaaat gaatcagata gatatgaaag gcttagatga tggaaacatc aataatatat     2040

atttcaatgc agaagcagga gctattgggg aaagtcatgg tattaatata atttgtgaaa     2100

cagttgataa acaaaataca atagaaaatg gcctttcttt aggagaaaaa agcactattc     2160

cagttcaaca agggttacct accagtaagt ctgagattac aaatcaatta tcagtctctg     2220

atattaacag tcaatctgtt ggaggggcca gacctaagca attgtttagc cttccatcaa     2280

gaacaaggag ttcaaaggac ctgaataagc cagatgttcc agatacaata gaaagtgaac     2340

ccagcacagc agataccgtt gttccaatca cttgtgctat agattctaca gctgatccac     2400

aggttagctt caactctaat tacattgata tagaaagtaa ttctgaaggt ggatctagtt     2460

tcgtaactgc aaatgaagat tctgtacctg aaaacacttg caaagaaggc ttggttttgg     2520

gccagaaaca gcctacttgg gttcctgatt cagaagctcc aaactgtatg aactgccaag     2580

tcaaatttac ttttaccaaa cggcgacacc attgccgagc atgtgggaaa gtattttgtg     2640

gtgtctgttg taataggaag tgtaaactgc aatatctaga aaaggaagca agagtatgtg     2700

tagtctgcta tgaaactatt agtaaagctc aggcatttga aaggatgatg agtccaactg     2760

gttctaatct taagtctaat cattctgatg aatgtactac tgtccagcct cctcaggaga     2820

accaaacatc cagtatacct tcaccagcaa ctttgccagt ctcagcactt aaacaaccag     2880

gtgttgaagg actatgttcc aaagaacaga agagagtatg gtttgcagat ggtatattgc     2940

ccaatggtga agttgcagat acaacaaaat tatcatctgg aagtaaaaga tgttctgaag     3000

actttagtcc tctctcacct gatgtgccta tgacagtaaa cacagtggat cattcccatt     3060

ctactacagt ggaaaagcca aacaatgaga caggagatat tacaagaaat gagataattc     3120

agagtcctat ttctcaggtt ccatcagtgg aaaaattgtc tatgaacaca ggaaatgagg     3180

ggttacctac ttctggttca tttacactag atgatgatgt ttttgcagaa actgaagaac     3240

catctagtcc tactggtgtc ttagttaaca gcaatttacc tattgctagt atttcagatt     3300

ataggttact gtgtgatatt aacaagtatg tctgcaataa gattagtctt ctacctaatg     3360

atgaggacag tttgccccca cttctggttg catctggaga aaagggatca gtgcctgtag     3420

tagaagaaca tccatctcat gagcagatca ttttgcttct tgaaggtgaa ggctttcatc     3480

ctgttacatt tgtcctaaat gctaatctac tcgtgaatgt caaattcata ttttattcct     3540

cagacaaata ttggtacttt tcaaccaatg gattgcatgg cttgggacag gcagaaatta     3600

ttattctatt gttatgtttg ccaaatgaag atactattcc taaggacatc ttcagactat     3660

ttatcaccat atataaggat gctctaaaag gaaaatacat agaaaacttg gacaatatta     3720

cctttactga gagttttctc agtagcaagg atcacggagg attcctgttt attacaccta     3780

cttttcagaa acttgatgat ctctcattac caagtaatcc ttttctttgt ggaattctta     3840

tccagaagct tgagattccc tgggcaaagg tttttcctat gcgtttaatg ttgagattgg     3900

gtgcagaata taaagcatat cctgctcctc taacaagcat cagaggccga aaacctcttt     3960

ttggagaaat aggacacact attatgaact tacttgttga ccttcgaaat taccagtata     4020

ccttgcataa tatagatcaa ctgttgattc atatggaaat gggaaaaagc tgcataaaaa     4080

taccacggaa aaagtacagt gatgtaatga aagtactaaa ttcttccaat gagcatgtca     4140

ttagcattgg agcaagtttc agtacagaag cagattctca tctagtctgt atacagaatg     4200

atggaattta tgaaacacag gccaacagtg ccactggcca tcctagaaaa gtgacaggtg     4260

caagttttgt ggtattcaat ggagctctaa aaacatcttc aggatttctt gctaagtcca     4320

gcatagttga agatggctta atggtacaaa taactccaga gaccatgaat ggcttgcggc     4380

tagctttacg agaacagaaa gactttaaaa ttacatgtgg gaaagttgat gcagtagacc     4440

tgagagaata cgtggatatc tgctgggtag atgctgaaga aaaaggaaac aaaggagtta     4500

tcagttcagt ggatggaata tcattacaag gatttccaag tgaaaaaata aaactggaag     4560

cagattttga aaccgatgag aagattgtaa aatgtaccga ggtgttctac tttctaaagg     4620

accaggattt atctatttta tcaacttctt atcagtttgc aaaagaaata gccatggctt     4680

gtagtgctgc gctgtgccct cacctgaaaa ctctaaaaag taatgggatg aataaaattg     4740

gactcagagt ttccattgac actgatatgg ttgaatttca ggcaggatct gaaggccaac     4800

ttctgcctca gcattatcta aatgatcttg atagtgctct gatacctgtg atccatggtg     4860

ggacctccaa ctctagttta ccattagaaa tagaattagt gtttttcatt atagaacatc     4920

ttttttagtg aaagaatgtg ccatattaca tattgcaacc taatttgtta aaactaactc     4980

cagcactaaa gctgaaatgc cacaaacact aaaagtataa atatgtctga tttttgaaac     5040

acataagctt tgctctttag gcaggaatga tcttttcaaa tcattagcac aatatttaaa     5100

tatctaaaaa tttaagagat ccatactttc tgtagcttta caattaattt aagtactaaa     5160

aagacaagga tttcttttaa gaaatttata gcatttactg tgttatttaa atgctaagcc     5220

aaagtatctg cacttaggta tacctcttta tgccaataat gattttaatg aaggctcttt     5280

tcagatgtaa ccttatgaag gaaatatctg ctttgtgtat atgccagtta gaatactggt     5340

ttctaaagtc tgtcaaattg tatttcagtg gcacaaaaac cagttttgag gtcttagact     5400

tataattctt tgaataaaac tgataactta tttgtataat tggagtggag acctacctcc     5460

ataattagat aaactctttt tggattataa tcagaatttt gccttttttc ttctcaaatt     5520

attacatatg tatgtattat atatccacat atatagtttt ccctgattaa atggatatta     5580

aaataattgc gggtgcttca ggactttttg cttctatatt taagtatatt gtttttatag     5640

caagaacata ttctgaatgt tttataaatc tttaataatt tatatgtagg taatattttt     5700

gtatcacaat gcattatttt tttcctcctt tccttccaaa ctataccact gtatttacca     5760

cttctaagag tgactgacga cgggccagat gacccttgaa gtagtcatta tgtagcaata     5820

aatgaagcct gaaacaggtt tttttacttc cactttaatc cttagaaatt tcttggcaac     5880

ttcgcatatt ttcattgaca ccagtgtata agtataaatt taaatgaact aattactttt     5940

gcatatttta aattctttat atggtagtta ttttttataa caggatatta acataagtta     6000

aatcctatgt atttgaaatt gttacagagc tttcctcttt acttcaaaca gcaaaaaagt     6060

ggggggcata ttgtagtcct gtcatttaag ttatgtaaaa aatttaatca ttattttgat     6120

gctttaaaca ttctcatgtg taatatatgt ttttgtatca aaaacactca tatatttcaa     6180

gaaaaagaaa ttatgttaaa tagccctgtt ttaagaaaaa tatttatgaa gcatctcaac     6240

ttgaagatca agtcaaagtt ataactcagg atctgaggtc tcaagctagg agagactgag     6300

aattttaatc agtttgggca tatagtttgg actgaatcac atctgtagta cttagccaaa     6360

gacaatttgg aggagaatat cagccttctg gaagtagcta cttcctgaac aatgtaaagt     6420

gtcgcagata ttcaataaaa tggcaacctg ttataatttg tgaaatttat tgaaatggtg     6480

taagatgaaa acaattgcat atcaaaccca atttatgttt tctaaatata gtgtatgtat     6540

tctgccatgt aagtaattga acagtcttaa aataaccaaa tggtagaggg ctgttccatg     6600

atgggacagc tttggatttg ttttcataaa atctctatat tcaataaaaa ttggaattat     6660

gtgcctgaag tttggaggca cattttgaag tattctttgt agacatatag tatgtttctg     6720

aatgtgtttg ttacttattt ggtcattggt acttaatttg aaattttaat tttttaagag     6780

aagaaataga atggttcttt gtactcagtc tgcaatgatc tatttttggc ttatgtcttt     6840

taatactact ctctttctct gaattttgaa atatgaagta aaatctagcc catttgtttt     6900

atgcagctat tcaacaaact ttgtgtgttc gtatacttgc tacatgcaga gcactttacc     6960

aggtttctaa gcaaaaattt ctaaaaatga ttaattgttc tgacagaatt aggcgtagtt     7020

ctttatcaac atttatggat tccatgccac aagtagtatg cgcttaagtg cagagcatgc     7080

caagagaaag agtaggattt ggccctgtag gagcaaagat tcaattgtgg gaaactactt     7140

gtttctgaaa attgcatgct aggatattta catcatgttc ctgttgaaaa caattcctga     7200

ttaaaataca agaataatct taaaacatca aagagatttt ccagacaata aggaatgcca     7260

agtccaaaag taaagagaat aagagaagca agcatgtacc cttactctga caaccttatg     7320

agtgaggggg acagaaatta aagttcaggg cccatataag gtgatgaacc taacaggaga     7380

ccctccacac aataggctga gactcccaaa tactttcacc                           7420


<210>  1032
<211>  6975
<212>  DNA
<213>  homo sapiens

<400>  1032
aactcgggaa cgggaacagg aggccgttgg aaaactttgg gcaagatggc ccggcggtga       60

tttccgcggc ggtctctcct gcgcccggcc tctgcggcgc aggcccagcc cccgagcctc      120

gcacgttcgg cagccccggc ctggccccgg cccctcctgc ccatggcggt ggccgagctg      180

tacacgcagt acaacagggt ctggattccc gatcctgaag aagtttggaa gtctgctgaa      240

atagccaagg actacagagt tggtgacaag gtcctgcgac tcctgctgga ggatggaacg      300

gagctggatt attctgtcaa tccagaatct ctgcctccac ttcggaatcc tgacatcctc      360

gtgggcgaga atgacctcac ggctctcagc tatcttcacg agcccgcggt gctccacaac      420

ctcagaatcc gctttgcaga atccaaactc atttacacct acagtggaat cattttggtg      480

gccatgaatc cttacaagca gttgccaata tacggagatg ccatcatcca cgcctacagc      540

gggcagaaca tgggcgatat ggacccacac atatttgccg tggcagaaga ggcatacaag      600

cagatggcca gaaacaacag aaaccagtcc ataattgtaa gtggggagtc aggtgctgga      660

aagacagtgt cggctcgcta tgccatgagg tactttgcca ccgtcagcaa atcgggcagc      720

aacgctcacg tggaagacaa ggtcctggca tccaatccca tcaccgaggc cgttggaaat      780

gccaagacca cccgcaatga caatagtagt cggtttggga aatacacaga aatcagtttt      840

gatgaacaaa atcaaattat aggagccaac atgagcactt acctcctgga gaaatccaga      900

gttgtctttc aatcggaaaa tgaacgaaat taccacattt tctatcagct ttgtgcatct      960

gcacagcagt cggaatttaa acatcttaaa ttggggagtg ccgaagaatt taattataca     1020

agaatgggag gcaatactgt cattgagggt gtgaatgatc gagctgaaat ggtagagact     1080

caaaagacct tcacgcttct gggtttcaag gaggattttc agatggacgt ttttaaaatc     1140

ctggcagcca tcctacatct gggcaatgtg cagatcaccg cggtgggcaa cgagaggtcc     1200

tcagttagtg aggatgacag tcacctgaag gtgttctgtg agctcctggg cctggagagt     1260

ggcagagttg ctcagtggct gtgcaatcgc aaaatcgtca caagctctga gacggtggta     1320

aaacccatga ccaggcctca ggctgtcaac gccagggatg cactggccaa aaagatctat     1380

gctcacctgt tcgacttcat tgtggagaga attaaccaag cgttgcagtt ttcaggcaag     1440

cagcacactt ttattggtgt tttggacatt tatggttttg aaacctttga tgtgaacagc     1500

tttgaacaat tttgcatcaa ttacgctaat gaaaaactgc aacaacagtt taacatgcat     1560

gtcttcaaac tggaacaaga agaatacatg aaggaagata taccttggac gctgatagat     1620

ttttatgaca atcaaccagt tattgacctg attgaagcaa aaatgggaat tctggagtta     1680

ctggatgaag aatgtttgtt accacatgga actgatgaaa actggcttca aaagctgtat     1740

aataattttg tcaacaggaa ccctttgttt gaaaagccta gaatgtcaaa cacatccttt     1800

gtcatccagc actttgctga taaggtagag tataaatgtg aaggtttcct ggagaaaaac     1860

agagacaccg tctatgacat gctggttgaa atcctgagag caagcaagtt tcatctctgt     1920

gccaactttt ttcaagaaaa tccaactcct ccttctcctt ttggttcaat gattacagtt     1980

aaatctgcaa agcaagtcat caagccaaac agcaagcatt tccggaccac agttgggagc     2040

aagttccgca gctctctgta cttgctcatg gagaccctca atgcgacgac gccccactac     2100

gttcgatgca tcaagccaaa tgatgagaag ttaccctttg aatttgactc caaaagaatt     2160

gttcagcagc tgcgagcctg cggcgtttta gaaacgattc gcattagtgc acagagctac     2220

ccttccaggt ggacatacat cgagttctac agtcgctacg gcattctcat gaccaagcaa     2280

gagctttcct tcagcgataa aaaggaggtg tgcaaggtgg ttttacacag actcatccag     2340

gattctaatc agtaccagtt tggtaaaacc aaaattttct tcagagcagg acaagtggct     2400

tatttagaga aacttcgatt ggataaactg aggcagagtt gtgttatggt acaaaagcac     2460

atgcgtggct ggctccagag gaaaaaattc ctccgagaga gacgagccgc cctgataatc     2520

cagcagtact tccggggtca gcaaactgtg aggaaagcta ttactgcagt ggccttaaaa     2580

gaagcttggg cagccataat cattcagaag cactgccgcg ggtatcttgt tcgcagcctg     2640

tatcagttga ttcgcatggc caccatcaca atgcaggcct acagccgagg attcctggca     2700

aggaggaggt atcgaaagat gctggaggaa cataaggctg tgatcctaca gaaatacgca     2760

cgggcgtggc tggccagacg cagattccag agtatccgac gattcgtgct taatattcag     2820

cttacttaca gggtccagcg tttgcagaaa aagttggaag atcagaacaa agaaaaccat     2880

gggctggtgg agaagctgac tagcctggct gctcttcgag ctggggatgt ggaaaagatt     2940

cagaagctgg aagcagaact agaaaaagca gccactcaca ggcgaaatta cgaggagaag     3000

gggaagagat acagggatgc tgtggaagag aaattggcaa agcttcagaa gcataattca     3060

gaactggaaa cacagaaaga acaaatacag ctgaagcttc aagagaagac tgaagagtta     3120

aaagaaaaaa tggacaacct caccaagcag ctctttgatg atgtacaaaa ggaagaacgg     3180

caaagaatgc ttcttgaaaa aagttttgaa ctgaaaacac aagactatga gaagcagatt     3240

cagtctttga aagaagaaat taaagctctc aaggatgaga agatgcaact ccaacacctg     3300

gtggaggggg agcacgtcac ttctgatggc ttgaaggcgg aagtggcccg cctgagcaag     3360

caggtcaaga caatctctga gttcgaaaaa gagatagaac tacttcaggc acagaagata     3420

gatgtggaga aacatgtgca gtcacaaaaa cgggaaatga gagaaaagat gtcagagatc     3480

accaaacaac ttctcgaaag ctatgacatt gaagatgtaa gaagcaggct ctctgtggaa     3540

gatctggaac atttaaatga ggatggagaa ctttggtttg cttatgaagg actaaagaaa     3600

gcaacacgtg ttttggagag ccatttccag tctcagaagg attgctatga aaaggagatt     3660

gaagctttga acttcaaagt ggtgcatctc agtcaagaaa tcaaccacct gcagaagtta     3720

ttcagagaag aaaatgacat caatgaaagc atccgtcatg aagttaccag gctaacatca     3780

gagaacatga tgatcccaga ctttaaacag caaatttcag aattggagaa acagaagcaa     3840

gatcttgaaa tccgcctgaa tgaacaagct gagaaaatga aaggaaaact agaagaattg     3900

tctaatcagt tacatcgcag tcaagaggag gaaggaacac aaagaaaggc cttggaagcc     3960

caaaatgaaa tacataccaa agagaaggag aagctgattg ataagattca agaaatgcag     4020

gaggccagtg accacttgaa gaaacaattt gaaactgaaa gtgaagtcaa gtgtaacttc     4080

cggcaggaag catcccggct cactttggaa aacagggatc ttgaagaaga attagacatg     4140

aaagacagag tgattaaaaa gctacaagat caagtcaaga cactaagcaa gacaattgga     4200

aaagccaatg atgtgcactc gtcctcagga cccaaggagt accttggaat gctgcaatac     4260

aagagagaag acgaggccaa gctcattcag aacctcattc ttgacttgaa gccccgtggc     4320

gtggtggtga acatgatccc cgggctgccg gctcatatcc tgttcatgtg tgtgcgctac     4380

gcagactctc tgaatgatgc caacatgctg aagtccctca tgaacagcac cattaatggc     4440

atcaagcagg tggttaagga acatttagaa gactttgaaa tgctgtcctt ttggctttcc     4500

aacacttgtc attttctcaa ttgcctgaag cagtacagcg gagaagagga attcatgaag     4560

cataatagtc cacagcagaa taagaattgc ttgaacaatt ttgacctttc agaatacaga     4620

cagattctca gtgatgtggc tatacgaata tatcatcaat ttattatcat aatggaaaag     4680

aatatccaac cgataatagt tccgggaatg ctggagtatg agagcctgca gggcatttcc     4740

ggcctgaagc ccacaggctt ccggaagcgc tcctctagca tagacgacac ggacggctac     4800

accatgacct ccgtcctgca acagctgagc tacttttaca ccaccatgtg ccagaacggc     4860

ctggaccccg agcttgtgag gcaggcggtg aagcagctct tcttcttgat cggggcggtc     4920

acgctgaaca gcctcttcct gcgcaaggac atgtgctcct gcagaaaagg gatgcagatc     4980

aggtgcaata tcagctactt agaagaatgg cttaaagata agaacttgca gaacagctta     5040

gcaaaggaaa ctttggagcc cctctctcag gcagcctggt tgcttcaggt caagaagacc     5100

acagacagtg atgccaagga gatctacgaa cgctgcacct cactgtctgc tgtgcagatc     5160

ataaagatcc ttaattcata cacacctata gatgactttg agaagagagt gactccatcc     5220

tttgttcgca aagtacaggc tctcctaaat agccgggagg attcatcaca gctgatgttg     5280

gataccaaat atctctttca agtcacattt ccttttaccc cctctccaca tgctctggaa     5340

atgattcaga tccccagcag tttcaagcta ggctttctga ataggttata gcaggagaaa     5400

aagtcaatgc actttttctt caaaagctaa gtgaaggttc aatatgaggg atgtgtttta     5460

ttaattggca gtggaaattg gaatgtgatt taaggaagaa aacagacttt tctcaaatgg     5520

accacatcat ctctcactca cagtgacaat gctgctcctg taattttgta agaattcaca     5580

cacaccagct gtatttggaa aagccatgtc tcactctcga atctcagctg gttttcactg     5640

aaattcctgg agggctcata ttttcttcca cgtgcctctt gatctgttct gtcttgtggc     5700

agggctctac caggagggag tgagatctgg ggacacagtg gcttccaagt tttctaaggt     5760

tcatgtgaaa cctgagtaca tttacaaagc tgcaagtgga ttctagtgct gagtcttcca     5820

ggaaaaaatc ccgtttggcc accgtgacct gccaaaagtt ctcttgcccc atgcctgctg     5880

gggacagaag gttttcatga actcttttta ctgaaaatgc cctgcattta aaaatgttta     5940

ttttagaccc ttctaaattt tttttttttt ttttttttga gactccggag tctcgctcta     6000

tcgccaggct ggagtgtagt ggcatgatct cggcttattg caacctccgc ttcctgggtt     6060

caaacaattc tcctgcctca gcctcctgag tagctgggac tacaggcacc tgccaccacg     6120

cccagctaat ttttgtattt ttagtggaga caggtttcac catgttggcc aggatggcct     6180

cgatctcttg acctcgtgat ccgcccacct cagcctccca aagtgctagg attacaggcg     6240

tgtgccaccg cgcccggctg acccttttaa tttttaagag tgttcaatcc gagatgaatc     6300

atttgaagta tttttatatg tatatctatt taaaactaat atattattaa agcttaattg     6360

ccatgccgtt tatcttctct gaaagaactt caaatcttac ctgccaacat attcaccata     6420

atttttttat tttttaatac ctttcataca ataacttttt taaaacaacc tcagattgaa     6480

aaagcaacct aaattacttt cgctctctaa tcagcatttc aatgtattta tttttaaatt     6540

ttctcaaaaa gtaactaaaa aattgtgtcg gaccctactt ttgagaaatc tacgtttccc     6600

aagttttatg ggaactggct attccttgtc ccggcacacc ttctcattcc ttcctttcag     6660

agcctaaaac ctcatttgat aagcactcct agtctctggc ctgtggatcc agtgctattc     6720

tgtcaccaac ctaagaatcc caattgcacc ttctgtttct gacagtcaca ggtgacagct     6780

gtgattctat aatacagact ggtgtcttag aggtaggaat aatacatgat tatgaagcat     6840

caccctgcta atacataata atgtcttttt atattataag tgattgagtt tagttcattt     6900

caatacattg tacatgaaaa aatgaaaagt agaactttgt aatactttaa tcaataaaat     6960

taattaccaa atgaa                                                      6975


<210>  1033
<211>  2938
<212>  DNA
<213>  homo sapiens

<400>  1033
gcgcacgtac acacgaaggg cctgctgact acatctgccg gaaagcatcg ggccaagcct       60

ttctccattt tgcggtctag gaagtagcag aggccccttc ctgtagggag ttgccatgga      120

gacgcggtgg ggcaccgacg gagttctaat gacggccgtg attggtgcag gatcctgcta      180

atctcaggaa ggcccgtaga gaagtgagga aaacgtggtg gggggcatgc gcgatctggt      240

aggcggtgct gccgtctgtt gtacctgaga ggcttgcgca tgccgacgca cggattcgag      300

gcggggagca tgggaagaag cggccaggag tatgacctga tcattgcgac caccgctagg      360

ggaagggagg agagggtgta gaaacgggga cgagggtggg ggaagggcaa ggaggcgctc      420

gagctggtgc gcggagcatc ctgggagacg tagtccagcg ggagggggaa gtcgaagact      480

gcgcgtgctc aggagcgcgg agcggcccgc tgagcgcaga ggggcagaca ctggcctcag      540

atacctgacc tggtaccctc tatgaggcct gcggtgctgg gctccccaga ccgagcaccc      600

ccagaagatg aggggcctgt catggtgaag ctagaggact ctgaggagga gggtgaggct      660

gccttatggg acccaggccc tgaagctgca cgcctgcgtt tccggtgctt ccgctatgag      720

gaggccacag ggccccaaga ggccctggcc cagctccgag agctgtgtcg ccagtggctg      780

cgtccagagg tacgctccaa ggagcagatg ctggagctgt tggtgctgga gcagttcctg      840

ggcgcactgc cccctgagat ccaggcccgt gtgcaggggc agcggccagg cagccccgag      900

gaggctgctg ccctagtaga tgggctgcgc cgggagccgg gcggaccccg gagatgggtc      960

acagtccagg tgcagggcca ggaggtccta tcagagaaga tggagccctc cagtttccag     1020

cccctacctg aaactgagcc tccaactcca gagcctgggc ccaagacacc tcctaggact     1080

atgcaggaat caccactggg cctgcaggtg aaagaggagt cagaggttac agaggactca     1140

gatttcctgg agtctgggcc tctagctgcc acccaggagt ctgtacccac cctcctgcct     1200

gaggaggccc agagatgtgg gaccgtgctg gaccagatct ttccccacag caagactggg     1260

cctgagggtc cctcatggag ggagcacccc agggccctgt ggcatgagga agctgggggc     1320

atcttctccc cagggttcgc gctgcagcta ggcagcatct ccgcaggtcc aggtagtgta     1380

agccctcacc tccacgtccc ctgggacctc ggcatggctg gcctttctgg ccagatccaa     1440

tcaccctccc gcgaaggtgg ctttgcgcat gcgcttctgc tccccagcga tctgaggagt     1500

gaacaggacc ccacggacga ggatccctgc cggggtgtgg gccctgctct gatcaccacc     1560

cgctggcgct cccccagggg ccggagccgg ggccgcccca gcactggggg cggggtggtt     1620

aggggcggcc gttgcgatgt atgtggcaag gtgttcagcc aacgcagcaa cctgctgagg     1680

caccagaaga tccacacggg tgagcgacca ttcgtgtgca gcgagtgcgg ccgcagcttc     1740

agccgcagct cgcacctgct gcgccaccag cttacgcaca ccgaggagcg gccgttcgtg     1800

tgcggcgact gtggccaggg cttcgtgcgc agcgcgcgcc tggaagagca tcggagagtg     1860

cacacgggcg aacagccttt ccgttgcgct gagtgcggcc agagcttccg gcagcgctcc     1920

aatctgctgc agcaccagcg catccacggc gatcccccgg gccctggcgc taagcccccg     1980

gcccctcctg gtgcgcccga gcctcccggc ccctttccgt gcagcgagtg ccgcgagagc     2040

ttcgcgcggc gcgccgtgct gctggagcac caggcggtac acacgggcga caagtccttt     2100

ggctgcgtcg agtgcggcga gcgcttcggc cgccgctcag tgctgctgca gcaccggcgc     2160

gtgcacagtg gcgagcggcc cttcgcctgt gccgagtgcg gccagagctt ccggcagcgc     2220

tccaacctga cgcagcaccg gcgcatccac accggggagc ggcccttcgc ctgcgccgag     2280

tgtggcaagg ccttccgcca gcggcctacg ctcacgcagc atctccgcgt acacacgggc     2340

gagaaaccct ttgcctgccc cgagtgtggc cagcgcttca gccagcgcct caagctcacg     2400

cgtcatcaga ggacacacac cggcgaaaag ccctaccact gcggtgagtg cggcctgggc     2460

ttcacgcagg tctcgcggct caccgagcac cagcgcatcc acacgggcga acggcccttc     2520

gcctgccccg agtgcggcca gagctttcgg cagcacgcca acctcaccca gcaccggcgc     2580

atccacacgg gtgaacggcc ctacgcatgc cctgagtgtg gcaaggcctt ccgccagcgg     2640

cccacgctca cgcagcatct gcgcacccac cgacgagaga agcccttcgc ctgccaggac     2700

tgtggccgcc gcttccacca gagcaccaag ctcattcagc accagcgcgt ccacagcgcc     2760

gagtagctcc agccgggacg cactgtgtcc gccatggtca gaacacctac ctcccctggt     2820

tattgtgagg ctggcgatta cataagtata agcaggtccg cccagggctt ggctactgta     2880

ggtgtccaat aaacagtaga tggaaactgg gtctccaccc aaaaaaaaaa aaaaaaaa       2938


<210>  1034
<211>  4410
<212>  DNA
<213>  homo sapiens

<400>  1034
gtgctcgggg gttccctggc cctttcggca ggggtaaaac aataagaggg ggcggtggca       60

aagggggcgg gacgtccgtg gtccttgtcg cacgtcgcag cgcctggcgc ccgggaagag      120

gtggttgtga ggcagacgaa ctcgcggctc tccggcttcc gaggcttccg agttgtcgga      180

ggaagggggc ggcgagcaat aagaacccgc cgcacccggt cctcagcgac tcttctgacc      240

tccgcgcgac gtacccgccg ccgccgttgg ctggagcatt tgacattgtg cagcaaagaa      300

atggttatgg agaagcccag tccgctgctt gtagggcggg agtttgtgag gcaatattat      360

actttgctga ataaagctcc ggaatattta cacaggtttt atggcaggaa ttcttcctat      420

gttcatggtg gagtagatgc tagtggaaag ccccaggaag ctgtttatgg ccaaaatgat      480

atacaccaca aagtattatc tctgaacttc agtgaatgtc atactaaaat tcgtcatgtg      540

gatgctcatg caaccttgag tgatggagta gttgtccagg tcatgggttt gctgtctaac      600

agtggacaac cagaaagaaa gtttatgcaa acctttgttc tggctcctga aggatctgtt      660

ccaaataaat tttatgttca caatgatatg tttcgttatg aagatgaagt gtttggtgat      720

tctgagcctg aacttgatga agaatcagaa gatgaagtag aagaggaaca agaagaaaga      780

caaccatctc ctgaacctgt gcaagaaaat gctaacagtg gttactatga agctcaccct      840

gtgactaatg gcatagagga gcctttggaa gaatcctctc atgaacctga acctgagcca      900

gaatctgaaa caaagactga agagctgaaa ccacaagtgg aggagaagaa cttagaagaa      960

ctagaggaga aatctactac tcctcctccg gcagaacctg tttctctgcc acaagaacca     1020

ccaaaggctt tctcctgggc ttcagtgacc agtaaaaacc tgcctcctag tggtactgtt     1080

tcttcctctg gaattccacc ccatgttaaa gcaccagtct cacagccaag agtcgaagct     1140

aaaccagaag ttcaatctca gccacctcgt gtgcgtgaac aacgacctag agaacgacct     1200

ggttttcctc ctagaggacc aagaccaggc agaggagata tggaacagaa tgactctgac     1260

aaccgtagaa taattcgcta tccagatagt catcaacttt ttgttggtaa cttgccacat     1320

gatattgatg aaaatgagct aaaggaattc ttcatgagtt ttggaaacgt tgtggaactt     1380

cgcatcaata ccaagggtgt tgggggaaag cttccaaatt ttggttttgt ggtttttgat     1440

gactctgaac cagttcagag aatcttaatt gcaaaaccga ttatgtttcg aggggaagta     1500

cgtttaaatg tggaagagaa aaaaacaaga gctgcaagag agcgagaaac cagaggtggt     1560

ggtgatgatc gcagggatat taggcgcaat gatcgaggtc ccggtggtcc acgtggaatt     1620

gtgggtggtg gaatgatgcg tgatcgtgat ggaagaggac ctcctccaag gggtggcatg     1680

gcacagaaac ttggctctgg aagaggaacc gggcaaatgg agggccgctt cacaggacag     1740

cgtcgctgaa gctccactgt tggcaaagtc ttggcagtgg tacattattc atcgtgtttg     1800

cattcttgtt aatttttttt ttggctttgg aatgtgacac agcctttttg atcatttctt     1860

tgatgtgaaa agcatctttg gttatcagtt aaattgaggt ggacattatt tccccaattt     1920

cacaacagga ttcacattgt taatttataa atctagactt ggagaattaa ggactgagaa     1980

atgaccatat cttaaactat ctacgacaaa gtgaacttaa aaggacatgc ccactgaatt     2040

caggtccttt gagtaaaaaa aaaatcttct gctgcacatt ttgtttaagt gttactgttt     2100

ctgcctgtta atgctgggaa cacaaatagt gcaatttgtg caattggaga atcttgcctt     2160

ttttcttggc tccccccaaa aatacaaacc aacagaaact tgttatgcac tcatcaaaat     2220

gtactaatgg gtactctgaa ctcattaaca ttgacatctg caacaggagg caacagggaa     2280

aaaatctcat cttcttttcc agtagaaaat agtttgtgaa atgatgaggg cattttatct     2340

gcttgctgtg accagcgtgt gtacacataa accttaacaa gactacaagt atattccaga     2400

aggaaatcat tttagttatg aactaaataa taaaaattag aacttcaaat gcgatggtct     2460

tgactattag accagattta gtagctccat atctaagatt tttctacctg cccctcttca     2520

gtacagggat ggctggctgc tcaacacact cctcctcccc ttttttcctt tctttaagct     2580

gtgtacagtg aaaattgtct ttactgtatt tttgttctct ggtaatgtaa taagcatgat     2640

ggtgccttct attaatacat cattccagtc ttgctggtaa ttttgtacag tatagtgtat     2700

gaattgctgt gctgcaaagc caaacagctg caaaatgttg aaaaatcatc gaaatgtata     2760

aaaattgcag tatctttaaa atcagtaaaa tggactagca tattatttat cttgttcttc     2820

agttaacaac tttgtgttct ctgtgggagg gagggagtcc tgtgtgtttg tggggagagg     2880

gaaggaggaa gtcagttatt tgagtaagcc tctagttgac ttttctctta gcctgaatgt     2940

ggacgttgaa acatatcact tcagggcttg gaaaagtcag tcaacttgac gtacattttt     3000

agtgacattt taaaagcagt cagattctat aaatggcaag taagcctgaa gtgaggatac     3060

tgcaattttc ggagaaaaga acagcagctc tttaagtgtt tgcattttct atttgggggg     3120

cagggaactg tcattcattt tgcacaattc ttgaactgat gtcagcaccc gagtggctcc     3180

tgaatttaag tctgggacga catcttttat ttttacatga atctttaaac aattctgtga     3240

gcaaagtttg tagctgctgg attattgtct gtctttatag caagttccag taaaccacaa     3300

gtatggcaaa gcttatccaa ttttatgctt ggagcagtca gtacatacca gtttctgatg     3360

tttcaggcag gagtggggta aataagtgtg accacttaaa gctgctcgtt agcatggaag     3420

acttctccat tctatctttg taaaacagac aagatatgca cttgacatag tagcaaattg     3480

gttctgaatt atgcaactgt ttgctattta gtaaactagc aaatgatgca tgtattttgt     3540

ttttcatgta ctgggcaata tgagtaaaat ctgtcccttt ttcccccttt gaatgaggtc     3600

ttccatgttt gagggaaagt cttgcactat tgcatatatt ttggggacac agattttcat     3660

agtttccatt tttggggggc ttaaggattt tttttttttc tgtttgaaac agttttatac     3720

tttctgatat agtacttgaa attcttacca gaaaattact ttggagtttt gaagccttta     3780

ttaatactac ttttaaagaa gcagttgttt tattgtcaat gttttttttc ccccaagcat     3840

attttcttgt atttctgttt ccatatatat atatatatat ataatttcca attcaggata     3900

ttgccctgcc atccatgaaa actgttctgg caccaaaagt aatgacaaat gttaagtgta     3960

ataatagaaa agtagagcaa agagccattc agcttcagtc tttacatacc atgaataaaa     4020

cattaaaaca tcatatggag aagtttacat ggtgattgtt cacctgcagt actgtggagt     4080

tttaacattt tgtcctcttt tcagtgaaac agagtaaaaa tattcatcta ccattactgt     4140

tatttgctga ttttgtttta ttttttgatg gtaatattct atccttatga cactattgca     4200

accaaattgg ctttaccatc ttggctttag taggtataga agacaatgga ttaccatctt     4260

tattgctgta atgtgttaag cattatatgc tagtagaatc tagtttaatt gtttcaggtg     4320

gaaagtattc tttgagtttc catattgaat gtgtttggac taaacaaaca ataaactact     4380

gatgtctgca gcatttatct atgtccctaa                                      4410


<210>  1035
<211>  4275
<212>  DNA
<213>  homo sapiens

<400>  1035
acattccatt cgcgctccgc ggcgcgaggc aatcgtccgg tgtgtgagcc cgggagccgg       60

aggtgtagcg gcagagacat tgttcttgcc ggctccctac ggtgccgtgt gtgcgtgaga      120

gaagaccagt ctttcctcta gcatttgaca ttgtgcagca aagaaatggt tatggagaag      180

cccagtccgc tgcttgtagg gcgggagttt gtgaggcaat attatacttt gctgaataaa      240

gctccggaat atttacacag gttttatggc aggaattctt cctatgttca tggtggagta      300

gatgctagtg gaaagcccca ggaagctgtt tatggccaaa atgatataca ccacaaagta      360

ttatctctga acttcagtga atgtcatact aaaattcgtc atgtggatgc tcatgcaacc      420

ttgagtgatg gagtagttgt ccaggtcatg ggtttgctgt ctaacagtgg acaaccagaa      480

agaaagttta tgcaaacctt tgttctggct cctgaaggat ctgttccaaa taaattttat      540

gttcacaatg atatgtttcg ttatgaagat gaagtgtttg gtgattctga gcctgaactt      600

gatgaagaat cagaagatga agtagaagag gaacaagaag aaagacaacc atctcctgaa      660

cctgtgcaag aaaatgctaa cagtggttac tatgaagctc accctgtgac taatggcata      720

gaggagcctt tggaagaatc ctctcatgaa cctgaacctg agccagaatc tgaaacaaag      780

actgaagagc tgaaaccaca agtggaggag aagaacttag aagaactaga ggagaaatct      840

actactcctc ctccggcaga acctgtttct ctgccacaag aaccaccaaa ggctttctcc      900

tgggcttcag tgaccagtaa aaacctgcct cctagtggta ctgtttcttc ctctggaatt      960

ccaccccatg ttaaagcacc agtctcacag ccaagagtcg aagctaaacc agaagttcaa     1020

tctcagccac ctcgtgtgcg tgaacaacga cctagagaac gacctggttt tcctcctaga     1080

ggaccaagac caggcagagg agatatggaa cagaatgact ctgacaaccg tagaataatt     1140

cgctatccag atagtcatca actttttgtt ggtaacttgc cacatgatat tgatgaaaat     1200

gagctaaagg aattcttcat gagttttgga aacgttgtgg aacttcgcat caataccaag     1260

ggtgttgggg gaaagcttcc aaattttggt tttgtggttt ttgatgactc tgaaccagtt     1320

cagagaatct taattgcaaa accgattatg tttcgagggg aagtacgttt aaatgtggaa     1380

gagaaaaaaa caagagctgc aagagagcga gaaaccagag gtggtggtga tgatcgcagg     1440

gatattaggc gcaatgatcg aggtcccggt ggtccacgtg gaattgtggg tggtggaatg     1500

atgcgtgatc gtgatggaag aggacctcct ccaaggggtg gcatggcaca gaaacttggc     1560

tctggaagag gaaccgggca aatggagggc cgcttcacag gacagcgtcg ctgaagctcc     1620

actgttggca aagtcttggc agtggtacat tattcatcgt gtttgcattc ttgttaattt     1680

tttttttggc tttggaatgt gacacagcct ttttgatcat ttctttgatg tgaaaagcat     1740

ctttggttat cagttaaatt gaggtggaca ttatttcccc aatttcacaa caggattcac     1800

attgttaatt tataaatcta gacttggaga attaaggact gagaaatgac catatcttaa     1860

actatctacg acaaagtgaa cttaaaagga catgcccact gaattcaggt cctttgagta     1920

aaaaaaaaat cttctgctgc acattttgtt taagtgttac tgtttctgcc tgttaatgct     1980

gggaacacaa atagtgcaat ttgtgcaatt ggagaatctt gccttttttc ttggctcccc     2040

ccaaaaatac aaaccaacag aaacttgtta tgcactcatc aaaatgtact aatgggtact     2100

ctgaactcat taacattgac atctgcaaca ggaggcaaca gggaaaaaat ctcatcttct     2160

tttccagtag aaaatagttt gtgaaatgat gagggcattt tatctgcttg ctgtgaccag     2220

cgtgtgtaca cataaacctt aacaagacta caagtatatt ccagaaggaa atcattttag     2280

ttatgaacta aataataaaa attagaactt caaatgcgat ggtcttgact attagaccag     2340

atttagtagc tccatatcta agatttttct acctgcccct cttcagtaca gggatggctg     2400

gctgctcaac acactcctcc tccccttttt tcctttcttt aagctgtgta cagtgaaaat     2460

tgtctttact gtatttttgt tctctggtaa tgtaataagc atgatggtgc cttctattaa     2520

tacatcattc cagtcttgct ggtaattttg tacagtatag tgtatgaatt gctgtgctgc     2580

aaagccaaac agctgcaaaa tgttgaaaaa tcatcgaaat gtataaaaat tgcagtatct     2640

ttaaaatcag taaaatggac tagcatatta tttatcttgt tcttcagtta acaactttgt     2700

gttctctgtg ggagggaggg agtcctgtgt gtttgtgggg agagggaagg aggaagtcag     2760

ttatttgagt aagcctctag ttgacttttc tcttagcctg aatgtggacg ttgaaacata     2820

tcacttcagg gcttggaaaa gtcagtcaac ttgacgtaca tttttagtga cattttaaaa     2880

gcagtcagat tctataaatg gcaagtaagc ctgaagtgag gatactgcaa ttttcggaga     2940

aaagaacagc agctctttaa gtgtttgcat tttctatttg gggggcaggg aactgtcatt     3000

cattttgcac aattcttgaa ctgatgtcag cacccgagtg gctcctgaat ttaagtctgg     3060

gacgacatct tttattttta catgaatctt taaacaattc tgtgagcaaa gtttgtagct     3120

gctggattat tgtctgtctt tatagcaagt tccagtaaac cacaagtatg gcaaagctta     3180

tccaatttta tgcttggagc agtcagtaca taccagtttc tgatgtttca ggcaggagtg     3240

gggtaaataa gtgtgaccac ttaaagctgc tcgttagcat ggaagacttc tccattctat     3300

ctttgtaaaa cagacaagat atgcacttga catagtagca aattggttct gaattatgca     3360

actgtttgct atttagtaaa ctagcaaatg atgcatgtat tttgtttttc atgtactggg     3420

caatatgagt aaaatctgtc cctttttccc cctttgaatg aggtcttcca tgtttgaggg     3480

aaagtcttgc actattgcat atattttggg gacacagatt ttcatagttt ccatttttgg     3540

ggggcttaag gatttttttt ttttctgttt gaaacagttt tatactttct gatatagtac     3600

ttgaaattct taccagaaaa ttactttgga gttttgaagc ctttattaat actactttta     3660

aagaagcagt tgttttattg tcaatgtttt ttttccccca agcatatttt cttgtatttc     3720

tgtttccata tatatatata tatatataat ttccaattca ggatattgcc ctgccatcca     3780

tgaaaactgt tctggcacca aaagtaatga caaatgttaa gtgtaataat agaaaagtag     3840

agcaaagagc cattcagctt cagtctttac ataccatgaa taaaacatta aaacatcata     3900

tggagaagtt tacatggtga ttgttcacct gcagtactgt ggagttttaa cattttgtcc     3960

tcttttcagt gaaacagagt aaaaatattc atctaccatt actgttattt gctgattttg     4020

ttttattttt tgatggtaat attctatcct tatgacacta ttgcaaccaa attggcttta     4080

ccatcttggc tttagtaggt atagaagaca atggattacc atctttattg ctgtaatgtg     4140

ttaagcatta tatgctagta gaatctagtt taattgtttc aggtggaaag tattctttga     4200

gtttccatat tgaatgtgtt tggactaaac aaacaataaa ctactgatgt ctgcagcatt     4260

tatctatgtc cctaa                                                      4275


<210>  1036
<211>  1622
<212>  DNA
<213>  homo sapiens

<400>  1036
gctttctttg tgtggctgaa gcgctagaaa tggcatattt tctttccctt cgttaaaaaa       60

tcagaccctc tttcccctct ctccccgcgg gaacacagct agggagtggg taggagcagg      120

atctgccgac gagggcagag gcggaaaatc ctcgggcgat gagctgaaga gggccgggtc      180

cgggagggat gctgggagct tgactcactc gcacaccatg tgtccctccg cgcgcagcac      240

gggggacttt tcggtgggga ttttgggcgc cgaccagacg cggcattttc ggaaaatagc      300

gccctgtgca gctgaagcgc tttgtgtgta gcggggccgc gtcagcccgg ccgggtacga      360

ggcgcctcgg gtccccgcac cacctcctgc tgccttcccg tcgccgctcc cgaagctttt      420

ccagatgtcc ctggtagatt tgggaaagaa gcttttagaa gcggcacgag caggtcaaga      480

tgatgaagtt cgtattttga tggcaaatgg agctcccttt actacagact ggctgggaac      540

ttctccactt catctagcag cacagtatgg tcattattcc accacagagg tactgctgcg      600

agctggtgtg agcagagatg ccagaaccaa agtggaccga acaccattac atatggcagc      660

ttctgagggc catgccagca tagtagaggt tttacttaag catggtgctg atgtcaatgc      720

aaaggacatg ttaaagatga cagctctcca ttgggccaca gaacacaatc atcaagaggt      780

ggtggaactt ttaatcaaat atggtgctga tgtacacacg caaagtaaat tttgtaaaac      840

tgcatttgat atttcaatag acaatggaaa tgaagattta gcagagatat tacagattgc      900

tatgcagaac caaatcaaca caaacccaga gagtcctgac actgtgacaa tacatgctgc      960

aacaccacag tttatcattg gacctggagg ggtggtgaac ctaacagatg aaacgggtgt     1020

atctgctgtt cagtttggaa actcttctac atcagtatta gctacattag ctgccttagc     1080

tgaagcatct gctccattgt ccaattcttc agaaactcca gtagtggcca cagaagaagt     1140

agttactgca gaatctgtgg atggtgccat tcagcaagta gttagttcag ggggtcagca     1200

agtcatcaca atagttacag atggaattca gcttggaaat ttgcactcta ttccaaccag     1260

tggaattggt cagcccatca ttgtgaccat gccagatgga caacaagtat taacagtacc     1320

agcaacagac attgctgaag aaactgttat aagtgaagaa ccaccagcta agagacaatg     1380

tatcgaaata attgaaaacc gggtggaatc tgcagaaata gaagtaagga gtcttttacc     1440

cggtgtgctt tgccgcagtc atccaaaata aattcaattt tttttgtctt ttatatttat     1500

tactgacagt attgttttga tacagaatga aagtgcgtag tattttcatt ttgtttattt     1560

ttgccttata catatagcaa gccctcaata aataaatatt gaatgaatga aaaaaaaaaa     1620

aa                                                                    1622


<210>  1037
<211>  1646
<212>  DNA
<213>  homo sapiens

<400>  1037
gctttctttg tgtggctgaa gcgctagaaa tggcatattt tctttccctt cgttaaaaaa       60

tcagaccctc tttcccctct ctccccgcgg gaacacagct agggagtggg taggagcagg      120

atctgccgac gagggcagag gcggaaaatc ctcgggcgat gagctgaaga gggccgggtc      180

cgggagggat gctgggagct tgactcactc gcacaccatg tgtccctccg cgcgcagcac      240

gggggacttt tcggtgggga ttttgggcgc cgaccagacg cggcattttc ggaaaatagc      300

gccctgtgca gctgaagcgc tttgtgtgta gcggggccgc gtcagcccgg ccgggtacga      360

ggcgcctcgg gtccccgcac cacctcctgc tgccttcccg tcgccgctcc cgaagctttt      420

ccaggtcaca gcatatttgt ggaggaagat gtccctggta gatttgggaa agaagctttt      480

agaagcggca cgagcaggtc aagatgatga agttcgtatt ttgatggcaa atggagctcc      540

ctttactaca gactggctgg gaacttctcc acttcatcta gcagcacagt atggtcatta      600

ttccaccaca gaggtactgc tgcgagctgg tgtgagcaga gatgccagaa ccaaagtgga      660

ccgaacacca ttacatatgg cagcttctga gggccatgcc agcatagtag aggttttact      720

taagcatggt gctgatgtca atgcaaagga catgttaaag atgacagctc tccattgggc      780

cacagaacac aatcatcaag aggtggtgga acttttaatc aaatatggtg ctgatgtaca      840

cacgcaaagt aaattttgta aaactgcatt tgatatttca atagacaatg gaaatgaaga      900

tttagcagag atattacaga ttgctatgca gaaccaaatc aacacaaacc cagagagtcc      960

tgacactgtg acaatacatg ctgcaacacc acagtttatc attggacctg gaggggtggt     1020

gaacctaaca gatgaaacgg gtgtatctgc tgttcagttt ggaaactctt ctacatcagt     1080

attagctaca ttagctgcct tagctgaagc atctgctcca ttgtccaatt cttcagaaac     1140

tccagtagtg gccacagaag aagtagttac tgcagaatct gtggatggtg ccattcagca     1200

agtagttagt tcagggggtc agcaagtcat cacaatagtt acagatggaa ttcagcttgg     1260

aaatttgcac tctattccaa ccagtggaat tggtcagccc atcattgtga ccatgccaga     1320

tggacaacaa gtattaacag taccagcaac agacattgct gaagaaactg ttataagtga     1380

agaaccacca gctaagagac aatgtatcga aataattgaa aaccgggtgg aatctgcaga     1440

aatagaagta aggagtcttt tacccggtgt gctttgccgc agtcatccaa aataaattca     1500

attttttttg tcttttatat ttattactga cagtattgtt ttgatacaga atgaaagtgc     1560

gtagtatttt cattttgttt atttttgcct tatacatata gcaagccctc aataaataaa     1620

tattgaatga atgaaaaaaa aaaaaa                                          1646


<210>  1038
<211>  3133
<212>  DNA
<213>  homo sapiens

<400>  1038
aaacagtcag ttatagtggg ttcaccagac tgttggagat ttgtgccata ggagctgtgc       60

atgcatgatg aagtggcaca gccactgaac ctatcagcta aacccaagac ctctgatggc      120

aaatcaccca catcacccac ctctccccat atgccagctc tgagaataaa cagtggggca      180

ggccccctca aagcctctgt cccagcagcg ttagctagtc cttcagccag agttagcaca      240

ataggttact taaatgacca tgatgctgtc accaaggcaa tccaagaagc tcggcaaatg      300

aaggagcaac tccgacggga acaacaggtg cttgatggga aggtggctgt tgtgaatagt      360

ctgggtctca ataactgccg aacagaaaag gaaaaaacaa cactggagag tctgactcag      420

caactggcag ttaaacagaa tgaagaagga aaatttagcc atgcaatgat ggatttcaat      480

ctgagtggag attctgatgg aagtgctgga gtctcagagt caagaattta tagggaatcc      540

cgagggcgtg gtagcaatga accccacata aagcgtccaa tgaatgcctt catggtgtgg      600

gctaaagatg aacggagaaa gatccttcaa gcctttcctg acatgcacaa ctccaacatc      660

agcaagatat tgggatctcg ctggaaagct atgacaaacc tagagaaaca gccatattat      720

gaggagcaag cccgtctcag caagcagcac ctggagaagt accctgacta taagtacaag      780

cccaggccaa agcgcacctg cctggtggat ggcaaaaagc tgcgcattgg tgaatacaag      840

gcaatcatgc gcaacaggcg gcaggaaatg cggcagtact tcaatgttgg gcaacaagca      900

cagatcccca ttgccactgc tggtgttgtg taccctggag ccatcgccat ggctgggatg      960

ccctcccctc acctgccctc ggagcactca agcgtgtcta gcagcccaga gcctgggatg     1020

cctgttatcc agagcactta cggtgtgaaa ggagaggagc cacatatcaa agaagagata     1080

caggccgagg acatcaatgg agaaatttat gatgagtacg acgaggaaga ggatgatcca     1140

gatgtagatt atgggagtga cagtgaaaac catattgcag gacaagccaa ctgataaggg     1200

tcaaaagatt gttgtgacct taggacttaa agaagcccta actggttcat ccttaccagt     1260

ggccaagcac attaactttc tcatacactg actgttactt taactgttag tcttaaatag     1320

ttgggacatc agctgactaa tagacctcag cctcaaaagg cttggaaaga aaaaacaaat     1380

acaacaagca aacaacaata tcaacaacaa gagattgaaa taagctatgg gtaaaataat     1440

gccagtaatt cagctgctac atccaagcac tgaagtctta cccgtcaact tttttttttt     1500

tttaaataaa ctttatggct gtttgttcta caatgttcta gaaattctca ctcaggtaca     1560

cagtgccaac aagtggcttg tgaatgtgtt ttgttgtttt gtgctacaat ttttaaaaag     1620

aaaaaagttt tgttttgttt tttggggttt ctgggttttt tccttttctt tttctttcct     1680

ttcatttttt ttctttgtaa tgcacctgac agaaaaaaaa gaaaaatgaa tttctcttta     1740

cttctctcca ccttctccat ctctctactt taaagatgga agtctgtgca tgaggggaaa     1800

gagggaaaaa gagcctgttt ttaacttcct tgctatccac cacaaaataa gcaattattt     1860

tctttagagg actttatcta ttgcacacca cactacatct ttgagcaagt gccaaatttg     1920

tactgaagtg ttgaccaagt tcattttttc tctttacttt ttccttttcc ttcttaagtt     1980

aggacagtgt taaatcttag acaatccctt gaaaaacctg aaataccagc agctggtgag     2040

atttgacttt tttttttaat ggaaactgta ggtgctgttc tcaggtgaaa agagagagag     2100

agagagagac ataagaaatt tagagaaaaa tattttctga tcttggattt ttgtgtgtat     2160

gtatgtatgt gattatggta ctaataatag gaataacgtt ggaccattgt gagttaaacc     2220

cacatctggg gatgaaatcc cacatcctcc caagtgactg gtctagaaat aatcttgacc     2280

ttgactttgc acttcaaatg acaacttaac caagtatagg gctcagaaat tatattttta     2340

aatgtctgat tattattgga tggatcaggt ggccctgtgt aatagaggtg tgcatgtata     2400

acatggaagc tactagcaaa ctgctcccag atgtcctttc tccctggtca gttggttcca     2460

ttaacgtttg ctacttagtg atttttgttt ttcctgttga tattttgagc aaaacaatca     2520

ttgttttcat tgaatatatt tggccatttt ttcagacaaa tagaattagc ttatttcttc     2580

aacattccat cctttcccga tcaggaaatg aaactgatga ttttataagg tatttttcac     2640

ccctccatga agtgaggtgg aggcctttag catttcagaa gtgtgggcca tatgtagttc     2700

atgccataaa aagtaggatt taattaaaag tcattgcagc ccaataaaat ggagcctggc     2760

tgcacccagg gatccttgcc actgctcttc ccttgctgtc agattaatcc actgaagtcc     2820

aactttggtt caagcagagt atttgcaaag agcaacaact gaatgtgatg ggactgctta     2880

tgtagatttt gccagccaaa tgccaaggca gttgtagggc ctgtacaaat aaatgcaaaa     2940

tcatttcaag tcaattgcca ttatttgtat tgaagtatca gatagatagt aaatactgca     3000

actagtagct tgatgtgcta tagttttcac tccagtcatc attttcctat ctcacccccc     3060

gaaacaccac cctaaagttg gatttttaca tataaataaa aaaagaatcc cttttaaaaa     3120

aaaaaaaaaa aaa                                                        3133


<210>  1039
<211>  4333
<212>  DNA
<213>  homo sapiens

<400>  1039
gagaaaatca attggtttag aaggtttgga ctcacttgac aggttcagtt ggagacgatc       60

ataggtggct gctgtgacaa agggaaattg tgcttttcca gcatgcttac tgaccctgat      120

ttacctcagg agtttgaaag gatgtcttcc aagcgaccag cctctccgta tggggaagca      180

gatggagagg tagccatggt gacaagcaga cagaaagtgg aagaagagga gagtgacggg      240

ctcccagcct ttcaccttcc cttgcatgtg agttttccca acaagcctca ctctgaggaa      300

tttcagccag tttctctgct gacgcaagag acttgtggcc ataggactcc cacttctcag      360

cacaatacaa tggaagttga tggcaataaa gttatgtctt catttgcccc acacaactca      420

tctacctcac ctcagaaggc agaagaaggt gggcgacaga gtggcgagtc cttgtctagt      480

acagccctgg gaactcctga acggcgcaag ggcagtttag ctgatgttgt tgacaccttg      540

aagcagagga aaatggaaga gctcatcaaa aacgagccgg aagaaacccc cagtattgaa      600

aaactactct caaaggactg gaaagacaag cttcttgcaa tgggatcggg gaactttggc      660

gaaataaaag ggactcccga gagcttagct gagaaagaaa ggcaactcat gggtatgatc      720

aaccagctga ccagcctccg agagcagctg ttggctgccc acgatgagca gaagaaacta      780

gctgcctctc agattgagaa acagcgtcag caaatggagc tggccaagca gcaacaagaa      840

caaattgcaa gacagcagca gcagcttcta cagcaacaac acaaaatcaa tttgctccag      900

caacagatcc aggttcaagg tcagctgccg ccattaatga ttcccgtatt ccctcctgat      960

caacggacac tggctgcagc tgcccagcaa ggattcctcc tccctccagg cttcagctat     1020

aaggctggat gtagtgaccc ttaccctgtt cagctgatcc caactaccat ggcagctgct     1080

gccgcagcaa caccaggctt aggcccactc caactgcagc agttatatgc tgcccagcta     1140

gctgcaatgc aggtatctcc aggagggaag ctgccaggca taccccaagg caaccttggt     1200

gctgctgtat ctcctaccag cattcacaca gacaagagca caaacagccc accacccaaa     1260

agcaaggatg aagtggcaca gccactgaac ctatcagcta aacccaagac ctctgatggc     1320

aaatcaccca catcacccac ctctccccat atgccagctc tgagaataaa cagtggggca     1380

ggccccctca aagcctctgt cccagcagcg ttagctagtc cttcagccag agttagcaca     1440

ataggttact taaatgacca tgatgctgtc accaaggcaa tccaagaagc tcggcaaatg     1500

aaggagcaac tccgacggga acaacaggtg cttgatggga aggtggctgt tgtgaatagt     1560

ctgggtctca ataactgccg aacagaaaag gaaaaaacaa cactggagag tctgactcag     1620

caactggcag ttaaacagaa tgaagaagga aaatttagcc atgcaatgat ggatttcaat     1680

ctgagtggag attctgatgg aagtgctgga gtctcagagt caagaattta tagggaatcc     1740

cgagggcgtg gtagcaatga accccacata aagcgtccaa tgaatgcctt catggtgtgg     1800

gctaaagatg aacggagaaa gatccttcaa gcctttcctg acatgcacaa ctccaacatc     1860

agcaagatat tgggatctcg ctggaaagct atgacaaacc tagagaaaca gccatattat     1920

gaggagcaag cccgtctcag caagcagcac ctggagaagt accctgacta taagtacaag     1980

cccaggccaa agcgcacctg cctggtggat ggcaaaaagc tgcgcattgg tgaatacaag     2040

gcaatcatgc gcaacaggcg gcaggaaatg cggcagtact tcaatgttgg gcaacaagca     2100

cagatcccca ttgccactgc tggtgttgtg taccctggag ccatcgccat ggctgggatg     2160

ccctcccctc acctgccctc ggagcactca agcgtgtcta gcagcccaga gcctgggatg     2220

cctgttatcc agagcactta cggtgtgaaa ggagaggagc cacatatcaa agaagagata     2280

caggccgagg acatcaatgg agaaatttat gatgagtacg acgaggaaga ggatgatcca     2340

gatgtagatt atgggagtga cagtgaaaac catattgcag gacaagccaa ctgataaggg     2400

tcaaaagatt gttgtgacct taggacttaa agaagcccta actggttcat ccttaccagt     2460

ggccaagcac attaactttc tcatacactg actgttactt taactgttag tcttaaatag     2520

ttgggacatc agctgactaa tagacctcag cctcaaaagg cttggaaaga aaaaacaaat     2580

acaacaagca aacaacaata tcaacaacaa gagattgaaa taagctatgg gtaaaataat     2640

gccagtaatt cagctgctac atccaagcac tgaagtctta cccgtcaact tttttttttt     2700

tttaaataaa ctttatggct gtttgttcta caatgttcta gaaattctca ctcaggtaca     2760

cagtgccaac aagtggcttg tgaatgtgtt ttgttgtttt gtgctacaat ttttaaaaag     2820

aaaaaagttt tgttttgttt tttggggttt ctgggttttt tccttttctt tttctttcct     2880

ttcatttttt ttctttgtaa tgcacctgac agaaaaaaaa gaaaaatgaa tttctcttta     2940

cttctctcca ccttctccat ctctctactt taaagatgga agtctgtgca tgaggggaaa     3000

gagggaaaaa gagcctgttt ttaacttcct tgctatccac cacaaaataa gcaattattt     3060

tctttagagg actttatcta ttgcacacca cactacatct ttgagcaagt gccaaatttg     3120

tactgaagtg ttgaccaagt tcattttttc tctttacttt ttccttttcc ttcttaagtt     3180

aggacagtgt taaatcttag acaatccctt gaaaaacctg aaataccagc agctggtgag     3240

atttgacttt tttttttaat ggaaactgta ggtgctgttc tcaggtgaaa agagagagag     3300

agagagagac ataagaaatt tagagaaaaa tattttctga tcttggattt ttgtgtgtat     3360

gtatgtatgt gattatggta ctaataatag gaataacgtt ggaccattgt gagttaaacc     3420

cacatctggg gatgaaatcc cacatcctcc caagtgactg gtctagaaat aatcttgacc     3480

ttgactttgc acttcaaatg acaacttaac caagtatagg gctcagaaat tatattttta     3540

aatgtctgat tattattgga tggatcaggt ggccctgtgt aatagaggtg tgcatgtata     3600

acatggaagc tactagcaaa ctgctcccag atgtcctttc tccctggtca gttggttcca     3660

ttaacgtttg ctacttagtg atttttgttt ttcctgttga tattttgagc aaaacaatca     3720

ttgttttcat tgaatatatt tggccatttt ttcagacaaa tagaattagc ttatttcttc     3780

aacattccat cctttcccga tcaggaaatg aaactgatga ttttataagg tatttttcac     3840

ccctccatga agtgaggtgg aggcctttag catttcagaa gtgtgggcca tatgtagttc     3900

atgccataaa aagtaggatt taattaaaag tcattgcagc ccaataaaat ggagcctggc     3960

tgcacccagg gatccttgcc actgctcttc ccttgctgtc agattaatcc actgaagtcc     4020

aactttggtt caagcagagt atttgcaaag agcaacaact gaatgtgatg ggactgctta     4080

tgtagatttt gccagccaaa tgccaaggca gttgtagggc ctgtacaaat aaatgcaaaa     4140

tcatttcaag tcaattgcca ttatttgtat tgaagtatca gatagatagt aaatactgca     4200

actagtagct tgatgtgcta tagttttcac tccagtcatc attttcctat ctcacccccc     4260

gaaacaccac cctaaagttg gatttttaca tataaataaa aaaagaatcc cttttaaaaa     4320

aaaaaaaaaa aaa                                                        4333


<210>  1040
<211>  2142
<212>  DNA
<213>  homo sapiens

<400>  1040
cggccccccg cattccccgc ccccacctcc ccgccttgtt gtccaacttc tcccggagca       60

gccggagagc aggcgtcggg acgcagcaaa gagaggagag accccagagt cagaaggagt      120

gagaaccctg acccctaatc ccactgcatc cagccaatag gagcccagcc accatggcgg      180

agctgcagga ggtgcagatc acagaggaga agccactgtt gccaggacag acgcctgagg      240

cggccaagga ggctgagtta gctgcccgaa tcctcctgga ccagggacag actcactctg      300

tggagacacc atacggctct gtcactttca ctgtctatgg cacccccaaa cccaaacgcc      360

cagcgatcct tacctaccac gatgtgggac tcaactataa atcttgcttc cagccactgt      420

ttcagttcga ggacatgcag gaaatcattc agaactttgt gcgggttcat gtggatgccc      480

ctggaatgga agagggagcc cctgtgttcc ctttgggata tcagtaccca tctctggacc      540

agcttgcaga catgatccct tgcgtcctgc agtacctaaa tttctctaca ataattggag      600

ttggtgttgg agctggagcc tacatcctgg cgagatatgc tcttaaccac ccggacactg      660

ttgaaggtct tgtcctcatc aacattgatc ccaatgccaa gggttggatg gattgggcag      720

cccacaagct aacaggcctc acctcttcca ttccggagat gatccttgga catcttttca      780

gccaggaaga gctctctgga aattctgagt tgatacaaaa gtacagaaat atcattacac      840

atgcacccaa cctggataac attgaattgt actggaacag ctacaacaac cgccgagacc      900

tgaactttga gcgtggaggt gatatcaccc tcaggtgtcc tgtgatgctg gtggtaggag      960

accaagcacc tcatgaagat gcagtggtgg aatgtaactc aaaactggac cccacccaga     1020

cctcgttcct caagatggct gactccggag gtcagcccca gctgactcag ccaggcaagc     1080

tgaccgaggc cttcaagtac ttcctgcaag gcatgggcta catggcctca tcctgcatga     1140

ctcgcctgtc ccggtctcgt acagcctctc tgaccagtgc agcatccgtt gatggcaacc     1200

ggtcccgctc tcgcaccctg tcccagagca gcgagtctgg aactctttct tcggggcccc     1260

cggggcacac catggaggtc tcctgttgaa tggcccttgt tgccctagag tgggacccag     1320

ccctcacctc ccccagagct aacctgggag gtgctgaagg ggcattgggc caccgtaagc     1380

aagggaaaaa gggcagatca tgcggggaga tgaccttgat ctttgattgc taccctaacc     1440

ttgaccttta acccgtgatt ccccccagct cctggaagag atgtcctaat atctcttagg     1500

gacccagacc cctaaattct cctcctcccc cattttgatg ttaaggtgga gagggcatat     1560

gcatcctctg tcctgatcta ggtgtctata gctgaggggt aagaggttgt tgtagttgtc     1620

ctggtgcctc catcagactc tccctacttg tcccatattt gcaaggggag gggatttggg     1680

gctggggctc cattcaccaa agctgaggtg gcttctcatt aaccctttag gactctgaag     1740

ggtatggacc tacgtgaatg tgtgtcaggg ggagacttgc tggtgggtta gtggtcctca     1800

ggatgtgata gaaacatcca gtgtaaaaag gaagttggaa tgggagttgg cgggcagtga     1860

acgagtgtgg ggaaggattg gtgctggggc aacaggaagg ggcctggggc cgtttggctg     1920

cactaacttt ggtagctcag tgtgcatcta gagtgggact ggggagggag ctaagcttgg     1980

gctgggctgc ttggggcttg gcatagggtg gaaagggcta ccctggggct ctgaccacac     2040

tgtagtatgt gtggagggtg ccctcccgtc tcccacaact tctgctataa caataaactg     2100

tagaggaatc tgagtaccgt taaaaaaaaa aaaaaaaaaa aa                        2142


<210>  1041
<211>  1921
<212>  DNA
<213>  homo sapiens

<400>  1041
ctgcctcccc cccgctcccg ctcccctgag cccagccaga ccccgcgccg cccgcgcccc       60

gctcgactcc ggaggctccc gcagccccgg cgtccgcccc gctgccccct cccccggggg      120

ccatgggggc gcccccgggc taccggccct cagcttgggt gcatctcctc caccagctgc      180

cccgcgccga cttccagctc cgcccggtgc ccagcgtttt cgcgccccaa gagcaggaat      240

accagcaggc cttgttgctg gtggcggcct tggcgggcct gggcttgggc ctgagcctca      300

ttttcatcgc tgtctacctc atccgcttct gctgctgccg gccccccgag ccccccgggt      360

ccaagatccc ctcgcccggg ggaggctgcg tcacctggag ctgcattgtc gcccttctcg      420

ccggctgcac tggcattggc atcggtttct atggcaacag tgagaccagt gatggggtgt      480

cccagctcag ctctgcgctg ctgcacgcca accacacact cagcaccatt gaccacctgg      540

tgttggagac ggtggagagg ctgggcgagg cggtgaggac agagctgacc accctggagg      600

aggtgctcga gccgcgcacg gagctggtgg ctgccgcccg aggggctcga cggcaggcgg      660

aggctgcggc ccagcagctg caggggctgg ccttctggca gggagtgccc ctgagccccc      720

tgcaggtggc tgaaaatgtg tcctttgtgg aggagtacag gtggctggcc tacgtcctcc      780

tgctgctcct ggagctgctg gtctgcctct tcaccctcct gggcctggcg aagcagagca      840

agtggctggt gatcgtgatg acagtcatga gtctcctggt tctcgtcctg agctggggct      900

ccatgggcct ggaggcagcc acggccgtgg gcctcagtga cttctgctcc aatccagacc      960

cttatgttct gaacctgacc caggaggaga cagggctcag ctcagacatc ctgagctatt     1020

atctcctctg caaccgggcc gtctccaacc ccttccaaca gaggctgact ctgtcccagc     1080

gagctctggc caacatccac tcccagctgc tgggcctgga gcgagaagct gtgcctcagt     1140

tcccttcagc gcagaagcct ctgctgtcct tggaggagac tctgaatgtg acagaaggaa     1200

atttccacca gttggtggca ctgctacact gccgcagcct gcacaaggac tatggtgcag     1260

ccctgcgggg cctgtgcgaa gacgccctgg aaggcctgct cttcctgcta ctcttctccc     1320

tgctgtctgc aggagcgctg gccactgccc tctgcagcct gccccgagcc tgggccctct     1380

tcccacccag tgacgactac gatgacacag acgatgacga ccctttcaac cctcaggaat     1440

ccaagcgctt tgtgcagtgg cagtcgtcta tctgagcccc tcctcccggc tggactggag     1500

cctggctccc ctcttcgttc cttccctggc tgccggagga gaccccacta acccagcctg     1560

cctgggctct gaccactaac actcttggcc atggacagcc tgcacaggac cgcctccctg     1620

ctcttggcca ctgtgctccc atttctgtcc ttggccttgg gagtagctga gggggcagac     1680

tagggagtag ggctggcagg ggagggggca gacagcctcg cctcgcaccc ttcatccctg     1740

gctgccggtc ccatccttgg agggactaag ctgggggtgg gggacatgag tccccctgct     1800

gcccctgcca catcccagtg ggctctgacc ccctgatctc aactcgtggc actaacttgg     1860

aaaagggttg atttaaaata aaagggaaga ctattttaca agcaaaaaaa aaaaaaaaaa     1920

a                                                                     1921


<210>  1042
<211>  8463
<212>  DNA
<213>  homo sapiens

<400>  1042
cgccctcctc tggagagaga ggctggagtg aggctgtgcg aagcgccgca tttcaatgag       60

gacgggccga ggcacatccc tgcactagtg gccgcaaccg aggcgccgcg ctccagcagc      120

tgctgccgcc cagcccggcc ccgccgccgc cccccagccc tgcagccccg cagccccggc      180

cgcgcccagc ccggcgagga cagcaccagg aggcggcccc cagcgcggcc acaaagaccc      240

ccggcggcgt ctctccgcgg accggtccta cttgaagtcc atcatgtcct tcggcagaga      300

catggagctg gagcacttcg acgagcggga taaggcgcag agatacagcc gagggtcgcg      360

ggtgaacggc ctgccgagcc cgacgcacag cgcccactgc agcttctacc gcacccgcac      420

gctgcagacg ctcagctccg agaagaaggc caagaaagtt cgtttctatc gaaacggaga      480

tcgatacttc aaagggattg tgtatgccat ctccccagac cggttccgat cttttgaggc      540

cctgctggct gatttgaccc gaactctgtc ggataacgtg aatttgcccc agggagtgag      600

aacaatctac accattgatg ggctcaagaa gatttccagc ctggaccaac tggtggaagg      660

agagagttat gtatgtggct ccatagagcc cttcaagaaa ctggagtaca ccaagaatgt      720

gaaccccaac tggtcggtga acgtcaagac cacctcggct tctcgggcag tgtcttcact      780

ggccactgcc aaaggaagcc cttcagaggt gcgagagaat aaggatttca ttcggcccaa      840

gctggtcacc atcatcagaa gtggcgtgaa gccacggaaa gctgtcagga ttctgctgaa      900

caagaaaacg gctcattcct ttgagcaggt cctcaccgat atcaccgatg ccatcaagct      960

ggactcggga gtggtgaaac gcctgtacac gttggatggg aaacaggtga tgtgccttca     1020

ggactttttt ggtgatgatg acatttttat tgcatgtgga ccggagaagt tccgttacca     1080

ggatgatttc ttgctagatg aaagtgaatg tcgagtggta aagtccactt cttacaccaa     1140

aatagcttca tcatcccgca ggagcaccac caagagccca ggaccgtcca ggcgtagcaa     1200

gtcccctgcc tccaccagct cagttaatgg aacccctggt agtcagctct ctactccgcg     1260

ctcaggcaag tcgccaagcc catcacccac cagcccagga agcctgcgga agcagaggag     1320

ctctcagcat ggcggctcct ctacgtcact tgcgtccacc aaagtctgca gctcgatgga     1380

tgagaacgat ggccctggag aagaagtgtc ggaggaaggc ttccagattc cagctacaat     1440

aacagaacga tataaagtcg gaagaacaat aggagatgga aattttgctg ttgtcaagga     1500

atgtgtagaa agatcgactg ctagagagta tgctctgaaa attatcaaga aaagcaaatg     1560

tcgaggcaaa gagcacatga tccagaatga agtgtctatt ttaagaagag tgaagcatcc     1620

caatatcgtt cttctgattg aggagatgga tgtgccaact gaactgtatc ttgtcatgga     1680

attagtaaag gggggagacc tttttgatgc cattacttcc actaacaaat acaccgagag     1740

agacgccagt gggatgctgt acaacctagc cagcgccatc aaatacctgc atagcctgaa     1800

catcgtccac cgtgatatca agccagagaa cctgctggtg tatgagcacc aagatggcag     1860

caaatcactg aagctgggtg actttggact ggccaccatt gtagacggcc ccctgtacac     1920

agtctgtggc accccaacat acgtggctcc agaaatcatt gcagagactg gatacggcct     1980

caaggtggac atctgggcag caggtgtaat cacttatatc ctgctgtgtg gtttccctcc     2040

attccgtgga agtggtgatg accaggaggt gctttttgat cagattttga tggggcaggt     2100

ggactttcct tctccatact gggataatgt ttccgattct gcaaaggagc tcattaccat     2160

gatgctgttg gtcgatgtag atcagcgatt ttctgctgtt caagtacttg agcatccctg     2220

ggttaatgat gatggcctcc cagaaaatga acatcagctg tcagtagctg gaaagataaa     2280

gaagcatttc aacacaggcc ccaagccgaa tagcacagca gctggagttt ctgtcatagc     2340

actggaccac gggtttacca tcaagagatc agggtctttg gactactacc agcaaccagg     2400

aatgtattgg ataagaccac cgctcttgat aaggagaggc aggttttccg acgaagacgc     2460

aaccaggatg tgaggagccg gtacaaggcg cagccagctc ctcccgaact caactcggaa     2520

tcggaagact actccccaag ctcctccgag actgttcgct cccctaactc gcccttttaa     2580

taagaccctt ttactcaaag tcctagctta accctttgag actctgagat ttttttcccc     2640

caaatttgtg taaaacagtt tcatctgatc tatctagcgc tcaatgcttg aatggcagaa     2700

ctgaaagtgt tttcaggtat ctttgtagcg gtttcccttt actgaataag atgacacgtg     2760

gtgattgtga agatggtaat ttgctgctaa tagagtcctc aaagggttaa ggccaatttg     2820

caattttttt ttaaacttag aagcaatgaa tgttttcatc agtcaagcta ggatctgcag     2880

tatgtaatat agcacttgtt aaccctctga gtgcatagaa ttttattgag aattcttgtt     2940

tgggaatttt tcaggccttt ggatgtatac acacatgttt cttgatttta ctgcagatca     3000

aggggtgttg ttagatgctg aaatgtccag aaaagaagga catttagaat gatatcttgt     3060

ttgtcctttt ctgtgggttt agaacgtggc aggtttataa cttcgacaca cgcacggttc     3120

tttcttcttc acaatcctat tcagaaacag attttttttt tcattagaga tatgactgtc     3180

agttgcagtg agttctgcat cccaagtgga gggaattggg tttgtggcaa agagcttgac     3240

ccaggaaata gatggtgccc cccaaattgt ctccacatga agatgtactg atgacgcccc     3300

agaaatgctg cttccatatc agctgctgct agcgccagcg cagactctca gggagtcacc     3360

acagcttgtc ttgtgcttgg tgagtgaggg tctctctact cagtgtcaga catctacagg     3420

aaagaaacaa ctggtggaaa agagcaataa attgcccggt gctctgcagg gctggaattt     3480

caaacagaaa gagggaataa gatcctgtga tttttctcac ctgcttttcc acgcactgtg     3540

gtcatcactg tgcaatctac atctagtatg aaatccacac ataggagagc tggggcacaa     3600

ggggactgga ggcagttgct ttgcaagatg gctgaggaga aagcacactg ggaacacaat     3660

ccagaatgtt ctaacaataa gttttcagtg aataaaccac tggcaagaca attccatgtg     3720

cacctttagg ttacctatat agtctcctag gaagatcagg atgaaagacc tagatgatac     3780

ccctgaggat aaaacctcca tcccctaaaa tgattttttt taaataccac tgtctttagc     3840

tgtccaggag gtcagagtgt tttttctgtc tttgggccaa gtcctgtctg agacctgtat     3900

tttcactctt gttaccaaat ctatctccct agtgcagtgt ctccaggcct gagtttcttc     3960

tggaacagat tccattttag aatggggatt cacaggttct gtgcatcacc acagtgctca     4020

gagaggattc tcctggggtg tcttagaggc aggtgcccaa ctcaaatgta ttcccaaggt     4080

ttgctgggct ctgggatcca cgagacaacc agagagggat atctcatgaa atttgcatct     4140

ggtggctgaa cagtacctat gttctctgtt ttgaatatac tttaatacct gagagtctta     4200

aaatttgtga acaacgtttc tatagtcctt tattttcaaa tgcacattga tcttcacttg     4260

ctgcattttt actcttcaac cctgaaacta tggtctacat taatatggat ttttaaatca     4320

catgtcatta cttttgcaac accatcacca aaattttttg ctcttttaca tttaggttca     4380

tctctgtggt ctgtgttgtc ctgacatgta aaaagcatat cgtttattga ggtttttttc     4440

cccccctttt agagcatccg gaagtgataa cacgcaaaat cacaaagtag cataaatcag     4500

taaattagtt gagttgtttt tgggggggag gtgggggtag ggggcacaga acaccagaaa     4560

gagtgttggt gtgtaggtag attccatatt aatgaggaac actgaactag ttggaaatta     4620

ctgctttctc tagaaatata aagcaaagca ctattccaag gctatggagt agctctacag     4680

cctggcctca actctaaaag tgtgaagaat gcaatgggca gagacctacc tgcagtggac     4740

tgtcattttc ctttctttct ctgaattact gctttttctg tgggcattaa ctatattgct     4800

acagcatcta gtgtactgag cctgcggtgc atggctcagg ccttttccca tcgacgtcta     4860

gggggactct ggaccgtgtg aagctagggg gtgtttctca gcacactgca gaagggcagc     4920

tcagaagaat gcagggccca ttcagcatgg ggatcccagc acatcactgt agaatttgag     4980

tgatctatgc tgaataaaca gtggaatgtg accagtcaag tagaaatctt gagtaatcag     5040

atggaatgca atctttctaa cattaagcta ccaagatcct gaatgtcaga gatgtactca     5100

gagggttaac agacaagcac aaggcatgct gactacattg gtgtatccag attgctttgc     5160

ttttagccag tgctttctaa tttttttctc gacattcttg ggatagttca agtttgaaat     5220

aattaagtgg tggtgttctt taaggaattt ctataaccaa attgatctta tttttgattt     5280

cacttatcat agaacaaata tgtatcatta tggcagtgta tctatgtaat tatcaattta     5340

atcatcacca ccggtgtttc catatttttt cccaagtatt taatatagct ctcttatggt     5400

ggtggcctgg tgatggggac cgtctttctt ttactgacac atgaccaatc atatggtatt     5460

ttcaagggaa ttttaagatt catcttttca gtttgatagt agactagtta aggaagaact     5520

ctttcattac ttgcatcgtg taaatcatct ctgtagacat gtgttcatat taatgaacac     5580

attttttctc aacattgtag cagaaatcat tttattcgtc atgatcaatg aatatgtgat     5640

ttgctccaga tcgttagaag gaaaagtaag atttcagtca tcaaaaatgt ttttaccgta     5700

gccctcatct aacttacacg tggtgcatat taaaataagc agagaaaaaa aaatgtgaat     5760

aaactactga aaacacttgg tgttttgtgt tcaatgagac cttcctgcaa cctgctcccc     5820

atgggtggca gttaacaggc ccatcagata ttgttgaaag aaagcaatat atccatgaat     5880

gaaggctaaa attgcaatcc tttacccttt gaggcatatt tcagttgaaa acaaaaagaa     5940

aagaaaattt ggcttagagg gtcacagagc tcccatatga ccaagtctca agcacattaa     6000

atcatggttg tttactggcc aagggcgtcc actagacaac tctatccctt gcgctgaagc     6060

tcaatcgtgc tgagggagag ctttcttaat attactgtgt tgctcttagc ccttctctgg     6120

gttaggatct gtcagcattt ctatgataaa ctcctattct caaaggtttt taatttgacc     6180

ataaaaatgt gccccaggct gaagtttgct atacagggct gtaccaaaga gtgaaggttt     6240

acttccttct ctttccaact tcttccccat tctccaagga aaagaacaac aaaaaaatct     6300

ggtatggtcc ctccttaata gtgatttcag aattttggaa agcaccaaga tccaagatgg     6360

tagttttaat gtagttactc attcgcacac attttttaaa tttaatgggt cacctggcat     6420

atattgtaga taacatatct tttctataat ttgtaagtca ataatttttt taactgctac     6480

atgatatttt tttttgccca aagattttaa aagacttgaa gttggtcagt tcaaaactca     6540

gatttttcta cacattgtct gccatgtcca ttaggagttt ggggaaaata ctctcacaca     6600

gacccttact ttgcatgcag tttagagggt aagatacgtg cttcttttgg ggataaagat     6660

ttccttactt aattgtcaaa tttcatggag ccattctagt ctgttgggga aaatagtgat     6720

taaaagcact tccaaaatta acattttttg acaattcaga tatgaaaaga agcaggggaa     6780

aataatacac tttactcttt tcttgcttaa aggcaaacaa atcaatgaaa cttgaggaca     6840

cactaaacat ttgataactg caaatgtgct ttaaaaattg gttcaatggt gcttacacat     6900

gaaacggtaa caaatggggt tcctaggacg tcagaaggaa tctttagttt gtatgtaatt     6960

acacactaga ggaggaggtg cttttaagcc agtcttttat ttttaatcat ctcaaatatg     7020

caaccataca tgcagtaaca ttaagggtcg taaactggtg ggaaacagga acttcagtgg     7080

agaggcttaa atgcctctgg ttagagtggg ggtttttgtt tgtttgttta ttgttgggtt     7140

tcaacactga gcatcatttc tgtgatcaag tttctaactg gcatgtgttt tgatcatgag     7200

gtttaccata tcttgcccat acagacaaat gagagatcta gtttcatttt gttccctaaa     7260

gaaagaacac tctctaaaat taaatcatac ctgtaaattt cttcagcatt tgtttctgtt     7320

caatgaaatt gagaccctta atgttgcttt aatgtaaaat tgaatatttt gtctgtgata     7380

tactttaata atttaaagta agtaatagtt ctaaagtctt cactgttgct actaagagaa     7440

aatagaattt taaaggtgat gataaagatg ctataatgtc agttcactcc agtccaatca     7500

aatgtagtaa gaaaaagtcc ttgaatagtt ctctagggac aatttctcac ttgccattga     7560

cattaatctt tggtgtattc tcagaaaaaa taaaaagaaa ttgaaactgg tccaaggtta     7620

tagtcatatc ctcgataact tttgaaaaaa aattttatta ggaaattaat actagccttt     7680

ttcattctgg ctgaaagaaa attattaaag gattagttga gtgtgaaatt caacagtatt     7740

ttgctcatac atactaaaaa ggtgcgtagg gacttggcgc atttaaacaa gtttctgaaa     7800

ggtttcaatt tgactcaaga aaaaaattca atatttcttt tgaaaatact gaatttatca     7860

cttgctgcat ggatcagatg gcataggtta atctttgatt ttcagaatcc taatgaaata     7920

actttcaaac aatttgtgtc cttaattaaa ggtggaatga gatccaattt ttccccctaa     7980

tccttcagtt taagctgata catgtaggtt aatgtggaat gaaatcatct gtgatatatt     8040

atgttcattt atcaactgag cttttttgat gttgcctgtt tttatgtaaa acatgttctt     8100

aaagttaata aaataatagt acttggtgta tgaactacta cataatacct tagctgaagg     8160

gtacgctcct cagttcattt gccatattgg agtaaaattt caccttagtt caattcacaa     8220

ttgacacatt cagttcacga aggaatagcc cagctgtgtt cttaggggga attctctcta     8280

tgcaaggctt taaaaattag tcatgcggtc agagtgtagc tttcccacat gtcctccata     8340

gcacagtgtg tatttcatga gcataattca aaaacagcta tttcaaaaat gtcccttgtc     8400

atatattacg ttcctgcctg ggccactgac ttggataaat acaaataaac caaataccat     8460

tca                                                                   8463


<210>  1043
<211>  4379
<212>  DNA
<213>  homo sapiens

<400>  1043
aaatgctact tgtaaacaag gctagaaagg gtggagaatg aaatgagatg gggggtgggg       60

aaacaaaccc tttagttaca atatcttagg gaaatgaatc tacaataaga caaatttcaa      120

atcaagttgc tccactatac tgcataagca gtttagaatc ttaagcagat gcaaaaagaa      180

taaagcaaat gggaggaaaa aaaaggccga taaagtttct ggctacaata caagagacat      240

atcattacca tatgatctaa tgtgggtgtc agccggattg tgttcattga gggaaacctt      300

attttttaac tgtgctatgg agtagaagca ggaggttttc aacctagtca cagagcagca      360

cctaccccct cctcctttcc acacctgcaa actcttttac ttgggctgaa tatttagtgt      420

aattacatct cagctttgag ggctcctgtg gcaaattccc ggattaaaag gttccctggt      480

tgtgaaaata catgagataa atcatgaagg ccactatcat cctccttctg cttgcacaag      540

tttcctgggc tggaccgttt caacagagag gcttatttga ctttatgcta gaagatgagg      600

cttctgggat aggcccagaa gttcctgatg accgcgactt cgagccctcc ctaggcccag      660

tgtgcccctt ccgctgtcaa tgccatcttc gagtggtcca gtgttctgat ttgggtctgg      720

acaaagtgcc aaaggatctt ccccctgaca caactctgct agacctgcaa aacaacaaaa      780

taaccgaaat caaagatgga gactttaaga acctgaagaa ccttcacgca ttgattcttg      840

tcaacaataa aattagcaaa gttagtcctg gagcatttac acctttggtg aagttggaac      900

gactttatct gtccaagaat cagctgaagg aattgccaga aaaaatgccc aaaactcttc      960

aggagctgcg tgcccatgag aatgagatca ccaaagtgcg aaaagttact ttcaatggac     1020

tgaaccagat gattgtcata gaactgggca ccaatccgct gaagagctca ggaattgaaa     1080

atggggcttt ccagggaatg aagaagctct cctacatccg cattgctgat accaatatca     1140

ccagcattcc tcaaggtctt cctccttccc ttacggaatt acatcttgat ggcaacaaaa     1200

tcagcagagt tgatgcagct agcctgaaag gactgaataa tttggctaag ttgggattga     1260

gtttcaacag catctctgct gttgacaatg gctctctggc caacacgcct catctgaggg     1320

agcttcactt ggacaacaac aagcttacca gagtacctgg tgggctggca gagcataagt     1380

acatccaggt tgtctacctt cataacaaca atatctctgt agttggatca agtgacttct     1440

gcccacctgg acacaacacc aaaaaggctt cttattcggg tgtgagtctt ttcagcaacc     1500

cggtccagta ctgggagata cagccatcca ccttcagatg tgtctacgtg cgctctgcca     1560

ttcaactcgg aaactataag taattctcaa gaaagccctc atttttataa cctggcaaaa     1620

tcttgttaat gtcattgcta aaaaataaat aaaagctaga tactggaaac ctaactgcaa     1680

tgtggatgtt ttacccacat gacttattat gcataaagcc aaatttccag tttaagtaat     1740

tgcctacaat aaaaagaaat tttgcctgcc attttcagaa tcatcttttg aagctttctg     1800

ttgatgttaa ctgagctact agagatattc ttatttcact aaatgtaaaa tttggagtaa     1860

atatatatgt caatatttag taaagctttt cttttttaat ttccaggaaa aaataaaaag     1920

agtatgagtc ttctgtaatt cattgagcag ttagctcatt tgagataaag tcaaatgcca     1980

aacactagct ctgtattaat ccccatcatt actggtaaag cctcatttga atgtgtgaat     2040

tcaatacagg ctatgtaaaa tttttactaa tgtcattatt ttgaaaaaat aaatttaaaa     2100

atacattcaa aattactatt gtatacaagc ttaattgtta atattcccta aacacaattt     2160

tatgaaggga gaagacattg gtttgttgac aataacagta catcttttca agttctcagc     2220

tatttcttct acctctccct atcttacatt tgagtatggt aacttatgtc atctatgttg     2280

aatgtaagct tataaagcac aaagcataca tttcctgact ggtctagaga actgatgttt     2340

caatttaccc ctctgctaaa taaatattaa aactatcatg tgacttcatg taatcaggct     2400

gaacatttct acaattacta gatgtattag acgtaagtat tttctttagt taaaccaccc     2460

atgttagaaa tgttttctgt agaatttata aacaactatc aatgcagaca atttaataag     2520

cctggggatg atttacttac agtaaacatt tatcaaattg tacatttgtg ctatcaacaa     2580

ttaataagca aatatgtgaa aatagtttct gtcttctatg aagttagata tttgatggtt     2640

aaaaccccta taaatcatag tttcatatgg gaaaaaataa ttgaaataca gtgtaaattt     2700

aaataattta ttaagtatag caaataattg aaatatggtg gactaaattt tgtcatagaa     2760

atatgtgcaa gttatagtag tggctcacat gagaggtaat caattctgct aatagtagca     2820

gaatgagtgc agtggaacat gaaaaacttg aggagataac agttgaggtg ggtttccata     2880

gatgcataat agttcaagag caagatttgg tggggaggca ctattcaaga cagggactaa     2940

gttcaaaatc caagacgtat gctgggacac acctctgaca ggttggcata aaggaggctt     3000

aatcaaacta tttttcttct tctgaaacag aagcaataat tttcatttac atttgacata     3060

tcccgaggta atattaacat tagggaaagt tactcttttc catctttcca cattcttgca     3120

ggaccataaa atctgaattt tccagtattt ttaataagag ggaagaaacc tctctttttc     3180

ttctcttttt catctcccaa gagatcctcc tctcatgact acagttgaat aggtggtttc     3240

tattggaaga cattcaggaa ttcaaggtgc atgtccataa atggactttt tttgttgttg     3300

ttcagagctg gaccttgaat gatgcatcct tctctctgtt gtaaccatga ataatgcacc     3360

cttcatgcta tagcctttaa cgattcaccc ttcttattgt aaccttgaat gattcaccct     3420

ttatggtgta gccttgagtg acgcaccctt catgttgtag ccttcaatga tgcacactcc     3480

atgttatagc cttgaatgat atacccttta tgctgcagcc tttctcttat ggggaaaagc     3540

ctgcagatat cctgctgctt aactgacaag tgtggtgaga aataagtaga aatctaaaga     3600

ggggaagacc attttggaca cttatctgca aggcagatcc aacacacttt tccagtagtc     3660

aagctacttc taattttgtt cagtatcaaa atgagaaaca ggcctgattc tccagcactc     3720

ttgtcaacac aacttccccc catatttata tatatacaca cacatatata tctttatata     3780

tatacacaca tatatatctt tatatatata tatttatata tatatctttt tgcatatata     3840

catatatatg tatctttatt tcctttgaaa taaagataaa tatagctgat ttctttggct     3900

tcgacactta ctatttgcat gactaaggga agctagttaa cctttctgtg actcatttcc     3960

ttgtccataa aatgggaata ttaattgtac atgtcttatg gattggtgtg tgaattcagt     4020

tagcgagtgt agaatataac ttatagatca aagtagagta aatggaaagg gctcaactat     4080

ggtgttgcta ctgccattgt tattacaggc acacagttcg agctataatc atttcaaggg     4140

aaattcttat gtgtcagttc tggatcgagg tctgagattc tgcatttcaa acaaacttcc     4200

aggaatgctg ctgcttcttg gtccacactt ggagaaataa gtcagcagag agtcctctcg     4260

tttcctattg taccatgtct gtcttttgtc tcctgcttat tggcctctgt aaggaactca     4320

cagctgctat aataaagtac caaaaactgg gtggcttaaa acaaaaaaaa aaaaaaaaa      4379


<210>  1044
<211>  5556
<212>  DNA
<213>  homo sapiens

<400>  1044
tttctcgctc gctcccgttc cccggacgcg gcggatgagc cggccccgct ggggaaggct       60

ccgggcggcg gcgggcggcc gggaggaggc tgcgtgctcg gggctggggc tgcgagcggg      120

gtgattttgt attaaaatga ggaggaggaa gaagaggcac ccacagcggc agcggcggcg      180

gcggcggcag cagcagcagg agcagcggcg gagagggctg cagcccgggc ggacgcgcgg      240

agccgagcgg ggcacggcgg cggcagcgac agcggccggg atgagtcaac taataattta      300

atgggggcag agacggcagc gaggggtaga gctagcgagg gagagagcga gagaagcagc      360

cccgtccggg gactcgcgct cacactcacg cacacacaca aacacacaca cacctctccc      420

tgtgccaccc agcaacaccc ggcctcgtca caacaacaac agccgcggcc gccctctatc      480

ctgcccgggg gcccagccga aagccagggc gactctagag gacgctgccc gcccccctct      540

ttcatttcgg gaaactcctg atcagttttg tcggggtttc tgggtttctt ttcccccaaa      600

gtcctagtgc cattgtggtg ctcgttgttt acctcggact ctggacgagt gagagcttgg      660

cgactttttg gggggagggg gcggggagtt tgtcgctgcc taggcggtgg aggtggctgg      720

gggtgccttc tgatcttcct cctcctcccc ctccccccga acctcttctc tcctcacttg      780

ctgggacccc agacgctcac agccccgcgt caatgggcag ggagagggtc cttgcggctg      840

ttgtcagcga gggcagaatc aaaagtggca ttttagtgcc tttccggggc ttttctcgcg      900

accccctgcc ccccaccctc gctgtccccc gctagatgcc ctcgttgggg gtgcgaggct      960

gtggggaaaa gtttaaggtt tgttaatatt agtcgcgatt gttggcgagg ggggtggggg     1020

tgattggaag ggaggcgagg tggccttccc aatgcgcgtt attcggggtt attgaagaat     1080

aatattgcaa gtgacagcca gaagtagact ttctgtcctc acaccgaaga acccgagtga     1140

gcaggaggga gggagagacg cgaagagacc ttttttcctt tttggagacc ttgtccgcag     1200

tgattttttt ttttttaaga gaatcctcag tcaccacgtc gtttccccag caccatcaca     1260

gtgtacagct cataacgggt tttgctttgt ttttacgatt tccccccaac gaatcacttg     1320

tcagatcaat tttatcttct tcctcctccc tgcttcccac tctcccctcc tccccatcgc     1380

aaaccctgtt ctctgaggtt agacatttta caaaccccta tatgttggtt ttcgaattgt     1440

gatttttttt ttaaacccct ttctcatggc tactcttcta gacgtttatt tctgcccttc     1500

ccccgcttag gggggcgggg gtaggggaaa ggaaaataat acaatttcag gggaagtcgc     1560

cttcaggtct gctgcttttt tatttttttt tttttaatta aaaaaaaaaa ggacatagaa     1620

aacatcagtc ttgaacttct cttcaagaac ccgggctgca aaggaaatct cctttgtttt     1680

tgttatttat gtgctgtcaa gttttgaagt ggtgatcttt agacagtgac tgagtatgga     1740

tcatttgaac gaggcaactc aggggaaaga acattcagaa atgtctaaca atgtgagtga     1800

tccgaagggt ccaccagcca agattgcccg cctggagcag aacgggagcc cgctaggaag     1860

aggaaggctt gggagtacag gtgcaaaaat gcagggagtg cctttaaaac actcgggcca     1920

tctgatgaaa accaacctta ggaaaggaac catgctgcca gttttctgtg tggtggaaca     1980

ttatgaaaac gccattgaat atgattgcaa ggaggagcat gcagaatttg tgctggtgag     2040

aaaggatatg cttttcaacc agctgatcga aatggcattg ctgtctctag gttattcaca     2100

tagctctgct gcccaggcca aagggctaat ccaggttgga aagtggaatc cagttccact     2160

gtcttacgtg acagatgccc ctgatgctac agtagcagat atgcttcaag atgtgtatca     2220

tgtggtcaca ttgaaaattc agttacacag ttgccccaaa ctagaagact tgcctcccga     2280

acaatggtcg cacaccacag tgaggaatgc tctgaaggac ttactgaaag atatgaatca     2340

gagttcattg gccaaggagt gccccctttc acagagtatg atttcttcca ttgtgaacag     2400

tacttactat gcaaatgtct cagcagcaaa atgtcaagaa tttggaaggt ggtacaaaca     2460

tttcaagaag acaaaagata tgatggttga aatggatagt ctttctgagc tatcccagca     2520

aggcgccaat catgtcaatt ttggccagca accagttcca gggaacacag ccgagcagcc     2580

tccatcccct gcgcagctct cccatggcag ccagccctct gtccggacac ctcttccaaa     2640

cctgcaccct gggctcgtat caacacctat cagtcctcaa ttggtcaacc agcagctggt     2700

gatggctcag ctgctgaacc agcagtatgc agtgaataga cttttagccc agcagtcctt     2760

aaaccaacaa tacttgaacc accctccccc tgtcagtaga tctatgaata agcctttgga     2820

gcaacaggtt tcgaccaaca cagaggtgtc ttccgaaatc taccagtggg tacgcgatga     2880

actgaaacga gcaggaatct cccaggcggt atttgcacgt gtggctttta acagaactca     2940

gggcttgctt tcagaaatcc tccgaaagga agaggacccc aagactgcat cccagtcttt     3000

gctggtaaac cttcgggcta tgcagaattt cttgcagtta ccggaagctg aaagagaccg     3060

aatataccag gacgaaaggg aaaggagctt gaatgctgcc tcggccatgg gtcctgcccc     3120

cctcatcagc acaccaccca gccgtcctcc ccaggtgaaa acagctacta ttgccactga     3180

aaggaatggg aaaccagaga acaataccat gaacattaat gcttccattt atgatgagat     3240

tcagcaggaa atgaagcgtg ctaaagtgtc tcaagcactg tttgcaaagg ttgcagcaac     3300

caaaagccag ggatggttgt gcgagctgtt acgctggaaa gaagatcctt ctccagaaaa     3360

cagaaccctg tgggagaacc tctccatgat ccgaaggttc ctcagtcttc ctcagccaga     3420

acgtgatgcc atttatgaac aggagagcaa cgcggtgcat caccatggcg acaggccgcc     3480

ccacattatc catgttccag cagagcagat tcagcaacag cagcagcaac agcaacagca     3540

gcagcagcag cagcaggcac cgccgcctcc acagccacag cagcagccac agacaggccc     3600

tcggctcccc ccacggcaac ccacggtggc ctctccagca gagtcagatg aggaaaaccg     3660

acagaagacc cggccacgaa caaaaatttc agtggaagcc ttgggaatcc tccagagttt     3720

catacaagac gtgggcctgt accctgacga agaggccatc cagactctgt ctgcccagct     3780

cgaccttccc aagtacacca tcatcaagtt ctttcagaac cagcggtact atctcaagca     3840

ccacggcaaa ctgaaggaca attccggttt agaggtcgat gtggcagaat ataaagaaga     3900

ggagctgctg aaggatttgg aagagagtgt ccaagataaa aatactaaca cccttttttc     3960

agtgaaacta gaagaagagc tgtcagtgga aggaaacaca gacattaata ctgatttgaa     4020

agactgagat aaaagtattt gtttcgttca acagtgccac tggtatttac taacaaaatg     4080

aaaagtccac cttgtcttct ctcagaaaac ctttgttgtt cattgtttgg ccaatgaatc     4140

ttcaaaaact tgcacaaaca gaaaagttgg aaaaggataa tacagactgc actaaatgtt     4200

ttcctctgtt ttacaaactg cttggcagcc ccaggtgaag catcaaggat tgtttggtat     4260

taaaatttgt gttcacggga tgcaccaaag tgtgtacccc gtaagcatga aaccagtgtt     4320

ttttgttttt tttttagttc ttattccgga gcctcaaaca agcattatac cttctgtgat     4380

tatgatttcc tctcctataa ttatttctgt agcactccac actgatcttt ggaaacttgc     4440

cccttattta aaaaaaaaaa agaaaaaaaa gagtttgtta ctctattgta tgttacaaaa     4500

gaactataga ctgtggaatg cagtttaaag atgacatatg ccaacaaatg ccttgtatta     4560

tatggcactg ccgtaattca aatttgtttt tattttggaa ataaaagttc actgtacttt     4620

tttttcattc tcattgttac atgatttttt aaaaaaagga aaagaaaatg tgaaacacaa     4680

tttagtcctc attatttatt tgtagatcct gcagcatcat gttgtaatta attttttgga     4740

agtttccgtt aaatgtaata ttgcttctct tgttaccata ctgattcttt tctatttata     4800

aatgtatttt gatgggcagt aaaacaaagt gtcttaaaag ttttaaatag agaaaatgtg     4860

ctttacacag ttgcctataa aaagtgctct atgttatcca agcaattcat actataagct     4920

tcactcttat tgttgtatgc aatttttact atcatgcaaa taagcttagg taaataaaac     4980

taatagatca ccttagaaaa ttatgcaatt aatgtgaaaa taattgatgt ttgcaatgtg     5040

tcttcctttg gtttacaatc aattttaaag ctacatctgt ataaaatttc tgtataaagg     5100

tgtatttctt ttttatgagt ttatggctat gaaaacagct attttgttac agctggctgt     5160

ttttataagt gtatcacaat tttctttatg cagaaatgtt ctgactagga gtggttattg     5220

actgtaacta cacaattaaa attgtttgta tcgtatgaca tggtagggtt tgtctgctta     5280

tgtgaagtaa ctaaaggagt caaaggatgg ccctctcatt taggtgcatg ttaataactt     5340

gttatttcac tgattttaaa aagagcaatt gacaagttac ttgaaacact gtaaatttaa     5400

atcacaaaca catgctcatt tttaaatagg tatgaaattt cacaatgaaa ataacctgtt     5460

tggttaacat tttgcttaat aagtagagat aggatggtca aaagactctc cgacaaaaac     5520

aaatccagtc tctagcagtt atgttgttag aatgga                               5556


<210>  1045
<211>  4814
<212>  DNA
<213>  homo sapiens

<400>  1045
ccggctttct tccgtcctgc cgtccccggg cccctagccc ccagtcccct ctcccccctc       60

cacctcttgt ccctcggcct ccgcgcctcc cctcccccga ctctctggcc tcccattcat      120

tccgtccgct ccctcccatt tcctcttttc cgctcgggcc ctctccccag agcctccccg      180

cgcggacccc gctgcagtct cggggttctc agcacattta tggaagttta gggcctggac      240

agtggccccg agtccggcct gagagcgcag cctgggctgc tggcagggaa gaggaagatg      300

tctgtgctca ggcggatgat gcgggtttcc aatcgctctc tcctcgcctt catcttcttc      360

ttctccctct cttcgtcctg tctgtacttc atctatgtgg ccccaggcat cgccaacaca      420

tatctcttta tggtacaagc tcgaggtata atgttgagag aaaatgtgaa aacaataggt      480

catatgatca ggctgtacac aaataaaaac agtacgctca acggtacaga ttatcccgaa      540

ggcaataatt caagtgatta tcttgttcaa acaacaacgt atctcccgga aaacttcaca      600

tactcaccat acctcccctg tccagaaaag ctgccttata tgcgaggatt cctcaatgtc      660

aatgtaagcg aagtcagttt tgatgaaatt catcaactct tctccaagga tttagatatt      720

gagccagggg gtcattggag gccaaaagac tgtaaaccca gatggaaggt ggcagttctc      780

attcctttcc gtaatcgcca tgaacatctt ccaatttttt tcttacatct gattccaatg      840

ctccagaagc agcggctgga atttgcgttt tatgtcattg aacagactgg cacacaacct      900

tttaaccgtg cgatgctttt caatgtgggc ttcaaagagg ccatgaaaga cagtgtctgg      960

gactgtgtaa tcttccacga tgtggatcat ctacctgaaa atgaccggaa ctattacgga     1020

tgtggagaaa tgccacgtca ttttgctgca aagctggata aatacatgta tattcttcca     1080

tataaagaat tttttggtgg tgtaagtggg ctgacagtgg aacaatttag aaagatcaat     1140

ggttttccta atgccttctg gggatgggga ggagaagatg atgacctttg gaacagagtt     1200

cactatgctg gatataatgt aaccagacca gagggagact taggaaaata caagtcaatt     1260

cctcatcacc atagaggtga agtccagttt ttaggacggt ataaattact aaggtattcc     1320

aaggagcgtc agtacatcga tggactgaac aatttaatat ataggccaaa aatactggtt     1380

gataggttgt atacaaacat atctgtaaac ctcatgccag agttagctcc aatcgaagac     1440

tattaaaaga agtggctgtc gtggcaaggt agaccacaat gctggatcat aaacttggag     1500

cgcgctctta gtggaggtca gtgattggct gtgtcacagt gcccttttct ctgagaagag     1560

ccagcagtcc acagtgttta cagagtggga ctatatacag tcacccttct ctcacccgtc     1620

ctccctgctc tgagacacac ccctgtggcg agcaccgcag aaacgggaag ccactactta     1680

agatcggaag ttaagagagc tccctccgaa gagaaaattt ttatactaaa atctataatt     1740

taattcaaga gaatgctttt atttccgttt aaacatattt tgtatatatg tgatataaat     1800

taatgtgtgc aaattgttta aaaattagat gtgttgcagt tttgcatgta atcggttata     1860

cctttattgg acttttatag acatttttta tttgcatgaa aaaaactcac taaatttaca     1920

tcactaaaca aaggttaacc cttgtgtgaa atgaaggaac tgtcaataat tgacagccaa     1980

ctaatacagt aaactgttat actagttttg agctttagac ctcagccttt tgtgtggaag     2040

aagtcacagc tttcttaggc tttaaaggaa aagaaggaag gacttaaata gcttttcttc     2100

ctaccgggat tacctatgtt tttccttgct tgcaatctca tctgattttg ctagaaatca     2160

caaccatatt gtttatgcat attgcatgag tattaccaag aaaaatctta aaagttgtga     2220

tgtgacatga tataaaggat ctctttatgt taaatgtctt tccatgtacc tctggtgtgt     2280

cagggatttt gtgcctcaaa aaatgtttcc aaggttgtgt gtttatactg tgtatttttt     2340

ttaaattcac ggtgaacagc acttttatta tttccagttc agaagagcca aaaaaaagta     2400

tcttcattta aaaagaaatc aagtcagttt ttttaaaaga atgatctatg gaagaaaacc     2460

caatagtact tataatatac aaatgaatta tactattaga taagaattaa atattctatt     2520

tttataaaga taaatactta gtagataaaa acaaatttta agtttagttt tcagacatag     2580

aatttcactt ttggagggga cccttgaatg ttagtttcat tcaaactata ttttgttttt     2640

ttcactttta agagattata tctctggtgt taattactaa aattttcttt ctaaaagtat     2700

aatttaatag aattatctta aaatacatga tcagtattca gtgcgctgat attataatgt     2760

cttctatatg tagtatctaa aagcataatt taatagcatt gtcttaaaat acgtgatgag     2820

ttatttggtg cactgatgcc ataatgtctt ctatatgtaa tatcttacat gtttgcatga     2880

gtgtcagggc tttgtccagt tatcttcata tgactgttct ctgaaaaaag gtcttactac     2940

ctgatatcaa gtacatatct taattttgga tgaatttttc cacagtaaag ccgaacagta     3000

ttcttttttg aaaattagca attataaaga ttgtttaaaa tatcttgata ttttcacaaa     3060

ttttaaacaa aaaattaaat atctataaag tgaatgttca acaacaatga tgagcaatag     3120

aaatctatat atgagaaacg tttggataat atttgcctca aggattgttt acctaaaaca     3180

gaactatggt tatttatctc agattgtaag ttttattttg aagtgtcatt tttatggcaa     3240

tattgataac acaaatgacc acaaactaaa tcataaaata attgaatcct tacactttga     3300

gaaaatggat agcttctgtg ttatgatacc aaacaaaata ttttcatatt tatttcttag     3360

aactatttcc aaaatattta tatttcagtt tttttatggt actcgaaaaa tcaaaccttc     3420

tgaaaattat gatatttgta cttcatttgt gtattagttc attttctgtt tctattacat     3480

agtttttaaa gtcaatgaaa gagattgaga atgttaacat ttgttgatca atgtggagct     3540

gtccacattc ggtatctttt catttttata tatattttac agtttcaaga aaacttagta     3600

ctactagtat ctgccttatt ttcttaagtc tgatgttaat ttttgtttca ggagtgagat     3660

ataaacattt tgcttttttt cagttttgaa atatagtttg tcatcctgtg aaaaccacct     3720

cgtttgcttt ttgtttgttt gttttgcttt tttagtgtag acctaaaatt atttttgcct     3780

ataaacagtg aacttaatat gtttctgtga gagtgacaga gctgtgcccg tttatcttca     3840

ttgtattaat tattacataa agattaacaa atacattgca aatgcaaatt ataggatgtt     3900

tggaggattt attaatgagc atgtattgat tgcctattcc atatccagtg caatgctagg     3960

tatgtctatg gaaggagtat tattacttca tttctaaaca aatgaagtca agcaaattga     4020

gatctttctg aaattatgaa gacatcttct gataacttat ctgttgtatt tcctagtctc     4080

aaagtcaaga aacccgtata tgtggaccta gggctaatag gaggtcccta tggcactaac     4140

tgggaaaatt acatggtgct tttcaactac agaaagaagt aatgactaat gggcctgtct     4200

gtagagaaga aaaggagaag agtacacatt tgctggaact atatataatt cacagtggag     4260

atagttaatt ctttgctaaa actagggttt tatgagtatt ttttaaatct acatttaagt     4320

ttttgttttt gtgaaaagtt attcagtaag aaaactttat aatattaagt agatacagtt     4380

atgtattaaa aatttcctta tatacccttt tgccagccaa gatactgata ttttaaaaca     4440

aaatggaaaa atgtccaata caatattctc tttctggagg cttcctacaa gtgaaagcag     4500

attttgtcat tttatttggc ctttgcttgt ctttgatata tttctttatg tgtttttcaa     4560

atacatactg ttgtagattt attgtcttgt atttgcaagt atgccggttg agagaactaa     4620

aatggttata gtattgttta tcagaaagag gaagtgtact taagattatt ttatttattt     4680

agatgaaagg cttctacata aatgcactga aataaatgct agtaatttct tgtatcccac     4740

ttcttttttt gcttctcatg gaaatgtttg tactttttta tcattgtctt ttatgaaata     4800

taatgttcta aaga                                                       4814


<210>  1046
<211>  2859
<212>  DNA
<213>  homo sapiens

<400>  1046
gcggagagga gggacgggct gggagagggc ccggactagg ggcggcgggc accgcaggag       60

ctccgcgcgg ctgcagcgcg ggcgggagcg gggacgcgat gtcgccgccg ccgcctcctt      120

gcgggccggg gctgcgcctc cggggctgag ccgccgccag agccgacagc cgagcagccg      180

ctgggcgctc ccgcggcgca ggaggatggg ctgcggcggg agccgggcgg atgccatcga      240

gccccgctac tacgagagct ggacccggga gacagaatcc acctggctca cctacaccga      300

ctcggacgcg ccgcccagcg ccgccgcccc ggacagcggc cccgaagcgg gcggcctgca      360

ctcgggcatg ctggaagatg gactgccctc caatggtgtg ccccgatcta cagccccagg      420

tggaataccc aacccagaga agaagacgaa ctgtgagacc cagtgcccaa atccccagag      480

cctcagctca ggccctctga cccagaaaca gaatggcctt cagaccacag aggctaaaag      540

agatgctaag agaatgcctg caaaagaagt caccattaat gtaacagata gcatccaaca      600

gatggacaga agtcgaagaa tcacaaagaa ctgtgtcaac tagcagagag tccaagcaga      660

agggcagatg gacttcttca gtgtccttca cggcactgga tcccatcaaa gaaccttgaa      720

gaagtggctg ccccttgctg gacctgaatt ctactgagtc cctggcaaga ctgtcttacc      780

tggcagcaaa ctgctgcctg atttgttggg accttctgag ccttctactt atcatgtaaa      840

tgtattggca cagtgcttac atatgttaat aaactgcaaa tgtgcagttc agtttgtctc      900

tttgcaactc ctgtaatacg gtctggtgta aaagtagtga gttaaagcta caggtcagtt      960

tatgaaacag aaaagtagga atgcattttc tgggtgaaag agtcacacct tagtgctata     1020

actctcctgc ccatgatagt gtattctgtt tcaggcaagc ttattctttc cttctttcat     1080

tttaaatatt gtcattacaa atcttaccag gttcacttaa aagctggctt tcatccaact     1140

ctaaacccac atattgaaaa aatcaaggta caggaaaact ccttgttatc cttgtttcct     1200

tagcttggta tgagacagat cggatccagt ttcccatgca ccaacccact gcccatggca     1260

tgtctttggg aggtgtctgt gaagcagtca tacctgctcc tcatctgcct ggaaagtcct     1320

cctattccag tgtccatgtt ggcctccagt ccttaatgtc accatgcttg tggccaatgc     1380

atccaaataa ggatacccct cagggctcag ctagacattg caattttgca tagctttcca     1440

gttccctttg cttgtcttct tgactgtctt ccctctctat cggggtcact tgcaattgtt     1500

aatcaaagat tgaacactgc gtaggagagg gagatgatcc agagacatgt ggcagcaggc     1560

atggcttccc cttggcctct ctgtacactg ccccaggact gtcattttgg catctgcaaa     1620

ggaatcactt tagaaagcca gcacctggtt gatgtgtatt catactgaca ttagattgat     1680

gtgcactgca ttagaaatga ggtagctgac acagaaaaag gatgttttga taggaataat     1740

tttctagtat gtcttgaaac atgttcatct ggaagtattt tcctccaaag taatgtagca     1800

tgatttttca aggattgtta acatgcctgg gattgggaaa gataggacta aagttgtgcc     1860

aaactatatc aataaattcc atgtttagca gaaataggca gcctattggt gttatgttta     1920

tgtaacatag tccagagaac tgacatgcag gtcaaaagtc agatacgcaa cctccttatc     1980

tgctaactct gttattcttc aaacacaagt gggtagtgtc atttttcctt ccttccttcc     2040

attggcagat tgtatattta ttcacaaaac attaaatgtc catcctgtgc caggtactat     2100

gcagatgttg agggatttgg ggtctggtta gtcgtgacta tctatcctga atctaacagt     2160

gacttcataa ctaggagact gaattagacc cttaaggtat agtgtgtgtt gcaaatcact     2220

ctgcaatgga aacttttata ttcagggtag gtttgtgtct taaactaggt gttctaatca     2280

atgtacaaga ctttaccata cacgcaacta tagtttttct aaaccttcat cattttgtga     2340

ttctttgaga aagggctttt aggaacttta tgttctaaaa aatgttttta acaataataa     2400

gataaaagaa aaacctgtga ttcatatgtc cccactggca ttactcagca ggagccccca     2460

gctgccaaag gttggcagtg atcctgcaag ttcaagggct ctttctccct ggggatgtgc     2520

tttgtggctt ctctttacag ctttgtttct gcatcagttc actgctgcat gttgtttgga     2580

atttatcacc ttaagaaagt gtctctgttt tatatagaaa cactttctca cttacagggg     2640

agaaggaaat gcagggcaca tgatctggcc ctccccagaa caatctggat ttcacggaga     2700

cagcaaccag aagttaaacc atgtgactaa aaatgcatct ggctactttt tcatgtatgt     2760

atgagacaga aactaatcct tactatccta ttaggatacc acttttcatt gcaaagtttg     2820

tgtcaataaa gtcattaatt ttaaacataa aaaaaaaaa                            2859


<210>  1047
<211>  2692
<212>  DNA
<213>  homo sapiens

<400>  1047
gcggagagga gggacgggct gggagagggc ccggactagg ggcggcgggc accgcaggag       60

ctccgcgcgg ctgcagcgcg ggcgggagcg gggacgcgat gtcgccgccg ccgcctcctt      120

gcgggccggg gctgcgcctc cggggctgag ccgccgccag agccgacagc cgagcagccg      180

ctgggcgctc ccgcggcgca ggaggatggg ctgcggcggg agccgggcgg atgccatcga      240

gccccgctac tacgagagct ggacccggga gacagaatcc acctggctca cctacaccga      300

ctcggacgcg ccgcccagcg ccgccgcccc ggacagcggc cccgaagcgg gcggcctgca      360

ctcgggctaa aagagatgct aagagaatgc ctgcaaaaga agtcaccatt aatgtaacag      420

atagcatcca acagatggac agaagtcgaa gaatcacaaa gaactgtgtc aactagcaga      480

gagtccaagc agaagggcag atggacttct tcagtgtcct tcacggcact ggatcccatc      540

aaagaacctt gaagaagtgg ctgccccttg ctggacctga attctactga gtccctggca      600

agactgtctt acctggcagc aaactgctgc ctgatttgtt gggaccttct gagccttcta      660

cttatcatgt aaatgtattg gcacagtgct tacatatgtt aataaactgc aaatgtgcag      720

ttcagtttgt ctctttgcaa ctcctgtaat acggtctggt gtaaaagtag tgagttaaag      780

ctacaggtca gtttatgaaa cagaaaagta ggaatgcatt ttctgggtga aagagtcaca      840

ccttagtgct ataactctcc tgcccatgat agtgtattct gtttcaggca agcttattct      900

ttccttcttt cattttaaat attgtcatta caaatcttac caggttcact taaaagctgg      960

ctttcatcca actctaaacc cacatattga aaaaatcaag gtacaggaaa actccttgtt     1020

atccttgttt ccttagcttg gtatgagaca gatcggatcc agtttcccat gcaccaaccc     1080

actgcccatg gcatgtcttt gggaggtgtc tgtgaagcag tcatacctgc tcctcatctg     1140

cctggaaagt cctcctattc cagtgtccat gttggcctcc agtccttaat gtcaccatgc     1200

ttgtggccaa tgcatccaaa taaggatacc cctcagggct cagctagaca ttgcaatttt     1260

gcatagcttt ccagttccct ttgcttgtct tcttgactgt cttccctctc tatcggggtc     1320

acttgcaatt gttaatcaaa gattgaacac tgcgtaggag agggagatga tccagagaca     1380

tgtggcagca ggcatggctt ccccttggcc tctctgtaca ctgccccagg actgtcattt     1440

tggcatctgc aaaggaatca ctttagaaag ccagcacctg gttgatgtgt attcatactg     1500

acattagatt gatgtgcact gcattagaaa tgaggtagct gacacagaaa aaggatgttt     1560

tgataggaat aattttctag tatgtcttga aacatgttca tctggaagta ttttcctcca     1620

aagtaatgta gcatgatttt tcaaggattg ttaacatgcc tgggattggg aaagatagga     1680

ctaaagttgt gccaaactat atcaataaat tccatgttta gcagaaatag gcagcctatt     1740

ggtgttatgt ttatgtaaca tagtccagag aactgacatg caggtcaaaa gtcagatacg     1800

caacctcctt atctgctaac tctgttattc ttcaaacaca agtgggtagt gtcatttttc     1860

cttccttcct tccattggca gattgtatat ttattcacaa aacattaaat gtccatcctg     1920

tgccaggtac tatgcagatg ttgagggatt tggggtctgg ttagtcgtga ctatctatcc     1980

tgaatctaac agtgacttca taactaggag actgaattag acccttaagg tatagtgtgt     2040

gttgcaaatc actctgcaat ggaaactttt atattcaggg taggtttgtg tcttaaacta     2100

ggtgttctaa tcaatgtaca agactttacc atacacgcaa ctatagtttt tctaaacctt     2160

catcattttg tgattctttg agaaagggct tttaggaact ttatgttcta aaaaatgttt     2220

ttaacaataa taagataaaa gaaaaacctg tgattcatat gtccccactg gcattactca     2280

gcaggagccc ccagctgcca aaggttggca gtgatcctgc aagttcaagg gctctttctc     2340

cctggggatg tgctttgtgg cttctcttta cagctttgtt tctgcatcag ttcactgctg     2400

catgttgttt ggaatttatc accttaagaa agtgtctctg ttttatatag aaacactttc     2460

tcacttacag gggagaagga aatgcagggc acatgatctg gccctcccca gaacaatctg     2520

gatttcacgg agacagcaac cagaagttaa accatgtgac taaaaatgca tctggctact     2580

ttttcatgta tgtatgagac agaaactaat ccttactatc ctattaggat accacttttc     2640

attgcaaagt ttgtgtcaat aaagtcatta attttaaaca taaaaaaaaa aa             2692


<210>  1048
<211>  2859
<212>  DNA
<213>  homo sapiens

<400>  1048
gcggagagga gggacgggct gggagagggc ccggactagg ggcggcgggc accgcaggag       60

ctccgcgcgg ctgcagcgcg ggcgggagcg gggacgcgat gtcgccgccg ccgcctcctt      120

gcgggccggg gctgcgcctc cggggctgag ccgccgccag agccgacagc cgagcagccg      180

ctgggcgctc ccgcggcgca ggaggatggg ctgcggcggg agccgggcgg atgccatcga      240

gccccgctac tacgagagct ggacccggga gacagaatcc acctggctca cctacaccga      300

ctcggacgcg ccgcccagcg ccgccgcccc ggacagcggc cccgaagcgg gcggcctgca      360

ctcgggcatg ctggaagatg gactgccctc caatggtgtg ccccgatcta cagccccagg      420

tggaataccc aacccagaga agaagacgaa ctgtgagacc cagtgcccaa atccccagag      480

cctcagctca ggccctctga cccagaaaca gaatggcctt cagaccacag aggctaaaag      540

agatgctaag agaatgcctg caaaagaagt caccattaat gtaacagata gcatccaaca      600

gatggacaga agtcgaagaa tcacaaagaa ctgtgtcaac tagcagagag tccaagcaga      660

agggcagatg gacttcttca gtgtccttca cggcactgga tcccatcaaa gaaccttgaa      720

gaagtggctg ccccttgctg gacctgaatt ctactgagtc cctggcaaga ctgtcttacc      780

tggcagcaaa ctgctgcctg atttgttggg accttctgag ccttctactt atcatgtaaa      840

tgtattggca cagtgcttac atatgttaat aaactgcaaa tgtgcagttc agtttgtctc      900

tttgcaactc ctgtaatacg gtctggtgta aaagtagtga gttaaagcta caggtcagtt      960

tatgaaacag aaaagtagga atgcattttc tgggtgaaag agtcacacct tagtgctata     1020

actctcctgc ccatgatagt gtattctgtt tcaggcaagc ttattctttc cttctttcat     1080

tttaaatatt gtcattacaa atcttaccag gttcacttaa aagctggctt tcatccaact     1140

ctaaacccac atattgaaaa aatcaaggta caggaaaact ccttgttatc cttgtttcct     1200

tagcttggta tgagacagat cggatccagt ttcccatgca ccaacccact gcccatggca     1260

tgtctttggg aggtgtctgt gaagcagtca tacctgctcc tcatctgcct ggaaagtcct     1320

cctattccag tgtccatgtt ggcctccagt ccttaatgtc accatgcttg tggccaatgc     1380

atccaaataa ggatacccct cagggctcag ctagacattg caattttgca tagctttcca     1440

gttccctttg cttgtcttct tgactgtctt ccctctctat cggggtcact tgcaattgtt     1500

aatcaaagat tgaacactgc gtaggagagg gagatgatcc agagacatgt ggcagcaggc     1560

atggcttccc cttggcctct ctgtacactg ccccaggact gtcattttgg catctgcaaa     1620

ggaatcactt tagaaagcca gcacctggtt gatgtgtatt catactgaca ttagattgat     1680

gtgcactgca ttagaaatga ggtagctgac acagaaaaag gatgttttga taggaataat     1740

tttctagtat gtcttgaaac atgttcatct ggaagtattt tcctccaaag taatgtagca     1800

tgatttttca aggattgtta acatgcctgg gattgggaaa gataggacta aagttgtgcc     1860

aaactatatc aataaattcc atgtttagca gaaataggca gcctattggt gttatgttta     1920

tgtaacatag tccagagaac tgacatgcag gtcaaaagtc agatacgcaa cctccttatc     1980

tgctaactct gttattcttc aaacacaagt gggtagtgtc atttttcctt ccttccttcc     2040

attggcagat tgtatattta ttcacaaaac attaaatgtc catcctgtgc caggtactat     2100

gcagatgttg agggatttgg ggtctggtta gtcgtgacta tctatcctga atctaacagt     2160

gacttcataa ctaggagact gaattagacc cttaaggtat agtgtgtgtt gcaaatcact     2220

ctgcaatgga aacttttata ttcagggtag gtttgtgtct taaactaggt gttctaatca     2280

atgtacaaga ctttaccata cacgcaacta tagtttttct aaaccttcat cattttgtga     2340

ttctttgaga aagggctttt aggaacttta tgttctaaaa aatgttttta acaataataa     2400

gataaaagaa aaacctgtga ttcatatgtc cccactggca ttactcagca ggagccccca     2460

gctgccaaag gttggcagtg atcctgcaag ttcaagggct ctttctccct ggggatgtgc     2520

tttgtggctt ctctttacag ctttgtttct gcatcagttc actgctgcat gttgtttgga     2580

atttatcacc ttaagaaagt gtctctgttt tatatagaaa cactttctca cttacagggg     2640

agaaggaaat gcagggcaca tgatctggcc ctccccagaa caatctggat ttcacggaga     2700

cagcaaccag aagttaaacc atgtgactaa aaatgcatct ggctactttt tcatgtatgt     2760

atgagacaga aactaatcct tactatccta ttaggatacc acttttcatt gcaaagtttg     2820

tgtcaataaa gtcattaatt ttaaacataa aaaaaaaaa                            2859


<210>  1049
<211>  8000
<212>  DNA
<213>  homo sapiens

<400>  1049
gagtagctcc agcggccacg ctgaggcgag ggtgacacac catgctcacg gcccctggag       60

accgtcgtgc tggcgagccg tgctccgtag ctccccggtc cgcctcggca gcggtcagag      120

tcgcctacag gagttgagcc gcccgcgcca gaaggttttg gcgaagctct tggagaggcg      180

tcgagcacag tagggcggcg ggggtgcgtt gagcgctcgg gggtcaggca gtcggccggg      240

atcgccgctg gggagcgttt ccgaggcgag gaggaggagg aggagatgct gctcctcttc      300

tccccctccc caggctcctt ctacagctcc ttcagcccac gcccgcagcc gcttgtggga      360

gaagtggtgg tggctctcgg cgcccgcggc ggctgccggc ggcccgcccc gacgccgcgt      420

ccctgcagcc ctcgcccggc gctccagtag caggacccgg tctcgggacc agccggtaat      480

atgcacgtgt cactagctga ggccctggag gttcggggtg gaccacttca ggaggaagaa      540

atatgggctg tattaaatca aagtgctgaa agtctccaag aattattcag aaaagtaagc      600

ctagctgatc ctgctgccct tggcttcatc atttctccat ggtctctgct gttgctgcca      660

tctggtagtg tgtcatttac agatgaaaat atttccaatc aggatcttcg agcattcact      720

gcaccagagg ttcttcaaaa tcagtcacta acttctctct cagatgttga aaagatccac      780

atttattctc ttggaatgac actgtattgg ggggctgatt atgaagtgcc tcagagccaa      840

cctattaagc ttggagatca tctcaacagc atactgcttg gaatgtgtga ggatgttatt      900

tacgctcgag tttctgttcg gactgtgctg gatgcttgca gtgcccacat taggaatagc      960

aattgtgcac cctcattttc ctacgtgaaa cacttggtaa aactggttct gggaaatctt     1020

tctgggacag atcagctttc ctgtaacagt gaacaaaagc ctgatcgaag ccaggctatt     1080

cgagatcgat tgcgaggaaa aggattacca acaggaagaa gctctacttc tgatgtacta     1140

gacatacaaa agcctccact ctctcatcag acctttctta acaaagggct tagtaaatct     1200

atgggatttc tgtccatcaa agatacacaa gatgagaatt atttcaagga cattttatca     1260

gataattctg gacgtgaaga ttctgaaaat acattctccc cttaccagtt caaaactagt     1320

ggcccagaaa aaaaacccat ccctggcatt gatgtgcttt ctaagaagaa gatctgggct     1380

tcatccatgg acttgctttg tacagctgac agagacttct cttcaggaga gactgccaca     1440

tatcgtcgtt gtcaccctga ggcagtaaca gtgcggactt caactactcc tagaaaaaag     1500

gaggcaagat actcagatgg aagtatagcc ttggatatct ttggccctca gaaaatggat     1560

ccaatatatc acactcgaga attgcccacc tcctcagcaa tatcaagtgc tttggaccga     1620

atccgagaga gacaaaagaa acttcaggtt ctgagggaag ccatgaatgt agaagaacca     1680

gttcgaagat acaaaactta tcatggtgat gtctttagta cctccagtga aagtccatct     1740

attatttcct ctgaatcaga tttcagacaa gtgagaagaa gtgaagcctc aaagaggttt     1800

gaatccagca gtggtctccc aggggtagat gaaaccttaa gtcaaggcca gtcacagaga     1860

ccgagcagac aatatgaaac accctttgaa ggcaacttaa ttaatcaaga gatcatgcta     1920

aaacggcaag aggaagaact gatgcagcta caagccaaaa tggcccttag acagtctcgg     1980

ttgagcctat atccaggaga cacaatcaaa gcgtccatgc ttgacatcac cagggatccg     2040

ttaagagaaa ttgccctaga aacagccatg actcaaagaa aactgaggaa tttctttggc     2100

cctgagtttg tgaaaatgac aattgaacca tttatatctt tggatttgcc acggtctatt     2160

cttactaaga aagggaagaa tgaggataac cgaaggaaag taaacataat gcttctgaac     2220

gggcaaagac tggaactgac ctgtgatacc aaaactatat gtaaagatgt gtttgatatg     2280

gttgtggcac atattggctt agtagagcat catttgtttg ctttagctac cctcaaagat     2340

aatgaatatt tctttgttga tcctgactta aaattaacca aagtggcccc agagggatgg     2400

aaagaagaac caaagaaaaa gaccaaagcc actgttaatt ttactttgtt tttcagaatt     2460

aaatttttta tggatgatgt tagtctaata caacatactc tgacgtgtca tcagtattac     2520

cttcagcttc gaaaagatat tttggaggaa aggatgcact gtgatgatga gacttcctta     2580

ttgctggcat ccttggctct ccaggctgag tatggagatt atcaaccaga ggttcatggt     2640

gtgtcttact ttagaatgga gcactatttg cccgccagag tgatggagaa acttgattta     2700

tcctatatca aagaagagtt acccaaattg cataatacct atgtgggagc ttctgaaaaa     2760

gagacagagt tagaattttt aaaggtctgc caaagactga cagaatatgg agttcatttt     2820

caccgagtgc accctgagaa gaagtcacaa acaggaatat tgcttggagt ctgttctaaa     2880

ggtgtccttg tgtttgaagt tcacaatgga gtgcgcacat tggtccttcg ctttccatgg     2940

agggaaacca agaaaatatc tttttctaaa aagaaaatca cattgcaaaa tacatcagat     3000

ggaataaaac atggcttcca gacagacaac agtaagatat gccagtacct gctgcacctc     3060

tgctcttacc agcataagtt ccagctacag atgagagcaa gacagagcaa ccaagatgcc     3120

caagatattg atgtgctaca caaaagatgg agcatagtat cttcaccaga aagggagatc     3180

accttagtga acctgaaaaa agatgcaaag tatggcttgg gatttcaaat tattggtggg     3240

gagaagatgg gaagactgga cctaggcata tttatcagtt cagttgcccc tggaggacca     3300

gctgacttgg atggatgctt gaagccagga gaccgtttga tatctgtgaa tagtgtgagt     3360

ctggagggag tcagccacca tgctgcaatt gaaattttgc aaaatgcacc tgaagatgtg     3420

acacttgtta tctctcagcc aaaagaaaag atatccaaag tgccttctac tcctgtgcat     3480

ctcaccaatg agatgaaaaa ctacatgaag aaatcttcct acatgcaaga cagtgctata     3540

gattcttctt ccaaggatca ccactggtca cgtggtaccc tgaggcacat ctcggagaac     3600

tcctttgggc catctggggg cctgcgggaa ggaagcctga gttctcaaga ttccaggact     3660

gagagtgcca gcttgtctca aagccaggtc aatggtttct ttgccagcca tttaggtgac     3720

caaacctggc aggaatcaca gcatggcagc ccttccccat ctgtaatatc caaagccacc     3780

gagaaagaga ctttcactga tagtaaccaa agcaaaacta aaaagccagg catttctgat     3840

gtaactgatt actcagaccg tggagattca gacatggatg aagccactta ctccagcagt     3900

caggatcatc aaacaccaaa acaggaatct tcctcttcag tgaatacatc caacaagatg     3960

aattttaaaa ctttttcttc atcacctcct aagcctggag atatctttga ggttgaactg     4020

gctaaaaatg ataacagctt ggggataagt gtcacgggag gtgtgaatac gagtgtcaga     4080

catggtggca tttatgtgaa agctgttatt ccccagggag cagcagagtc tgatggtaga     4140

attcacaaag gtgatcgcgt cctagctgtc aatggagtta gtctagaagg agccacccat     4200

aagcaagctg tggaaacact gagaaataca ggacaggtgg ttcatctgtt attagaaaag     4260

ggacaatctc caacatctaa agaacatgtc ccggtaaccc cacagtgtac cctttcagat     4320

cagaatgccc aaggtcaagg cccagaaaaa gtgaagaaaa caactcaggt caaagactac     4380

agctttgtca ctgaagaaaa tacatttgag gtaaaattat ttaaaaatag ctcaggtcta     4440

ggattcagtt tttctcgaga agataatctt ataccggagc aaattaatgc cagcatagta     4500

agggttaaaa agctctttcc tggacagcca gcagcagaaa gtggaaaaat tgatgtagga     4560

gatgttatct tgaaagtgaa tggagcctct ttgaaaggac tatctcagca ggaagtcata     4620

tctgctctca ggggaactgc tccagaagta ttcttgcttc tctgcagacc tccacctggt     4680

gtgctaccgg aaattgatac tgcgcttttg accccacttc agtctccagc acaagtactt     4740

ccaaacagca gtaaagactc ttctcagcca tcatgtgtgg agcaaagcac cagctcagat     4800

gaaaatgaaa tgtcagacaa aagcaaaaaa cagtgcaagt ccccatccag aagagacagt     4860

tacagtgaca gcagtgggag tggagaagat gacttagtga cagctccagc aaacatatca     4920

aattcgacct ggagttcagc tttgcatcag actctaagca acatggtatc acaggcacag     4980

agtcatcatg aagcacccaa gagtcaagaa gataccattt gtaccatgtt ttactatcct     5040

cagaaaattc ccaataaacc agagtttgag gacagtaatc cttcccctct accaccggat     5100

atggctcctg ggcagagtta tcaaccccaa tcagaatctg cttcctctag ttcgatggat     5160

aagtatcata tacatcacat ttctgaacca actagacaag aaaactggac acctttgaaa     5220

aatgacttgg aaaatcacct tgaagacttt gaactggaag tagaactcct cattacccta     5280

attaaatcag aaaaaggaag cctgggtttt acagtaacca aaggcaatca gagaattggt     5340

tgttatgttc atgatgtcat acaggatcca gccaaaagtg atggaaggct aaaacctggg     5400

gaccggctca taaaggttaa tgatacagat gttactaata tgactcatac agatgcagtt     5460

aatctgctcc gggctgcatc caaaacagtc agattagtta ttggacgagt tctagaatta     5520

cccagaatac caatgttgcc tcatttgcta ccggacataa cactaacgtg caacaaagag     5580

gagttgggtt tttccttatg tggaggtcat gacagccttt atcaagtggt atatattagt     5640

gatattaatc caaggtccgt cgcagccatt gagggtaatc tccagctatt agatgtcatc     5700

cattatgtga acggagtcag cacacaagga atgaccttgg aggaagttaa cagagcatta     5760

gacatgtcac ttccttcatt ggtattgaaa gcaacaagaa atgatcttcc agtggtcccc     5820

agctcaaaga ggtctgctgt ttcagctcca aagtcaacca aaggcaatgg ttcctacagt     5880

gtggggtctt gcagccagcc tgccctcact cctaatgatt cattctccac ggttgctggg     5940

gaagaaataa atgaaatatc gtaccccaaa ggaaaatgtt ctacttatca gataaaggga     6000

tcaccaaact tgactctgcc caaagaatct tatatacaag aagatgacat ttatgatgat     6060

tcccaagaag ctgaagttat ccagtctctg ctggatgttg tggatgagga agcccagaat     6120

cttttaaacg aaaataatgc agcaggatac tcctgtggtc caggtacatt aaagatgaat     6180

gggaagttat cagaagagag aacagaagat acagactgcg atggttcacc tttacctgag     6240

tattttactg aggccaccaa aatgaatggc tgtgaagaat attgtgaaga aaaagtaaaa     6300

agtgaaagct taattcagaa gccacaagaa aagaagactg atgatgatga aataacatgg     6360

ggaaatgatg agttgccaat agagagaaca aaccatgaag attctgataa agatcattcc     6420

tttctgacaa acgatgagct cgctgtactc cctgtcgtca aagtgcttcc ctctggtaaa     6480

tacacgggtg ccaacttaaa atcagtcatt cgagtcctgc ggggtttgct agatcaagga     6540

attccttcta aggagctgga gaatcttcaa gaattaaaac ctttggatca gtgtctaatt     6600

gggcaaacta aggaaaacag aaggaagaac agatataaaa atatacttcc ctatgatgct     6660

acaagagtgc ctcttggaga tgaaggtggc tatatcaatg ccagcttcat taagatacca     6720

gttgggaaag aagagttcgt ttacattgcc tgccaaggac cactgcctac aactgttgga     6780

gacttctggc agatgatttg ggagcaaaaa tccacagtga tagccatgat gactcaagaa     6840

gtagaaggag aaaaaatcaa atgccagcgc tattggccca acatcctagg caaaacaaca     6900

atggtcagca acagacttcg actggctctt gtgagaatgc agcagctgaa gggctttgtg     6960

gtgagggcaa tgacccttga agatattcag accagagagg tgcgccatat ttctcatctg     7020

aatttcactg cctggccaga ccatgataca ccttctcaac cagatgatct gcttactttt     7080

atctcctaca tgagacacat ccacagatca ggcccaatca ttacgcactg cagtgctggc     7140

attggacgtt cagggaccct gatttgcata gatgtggttc tgggattaat cagtcaggat     7200

cttgattttg acatctctga tttggtgcgc tgcatgagac tacaaagaca cggaatggtt     7260

cagacagagg atcaatatat tttctgctat caagtcatcc tttatgtcct gacacgtctt     7320

caagcagaag aagagcaaaa acagcagcct cagcttctga agtgacatga aaagagcctc     7380

tggatgcatt tccatttctc tccttaacct ccagcagact cctgctctct atccaaaata     7440

aagatcacag agcagcaagt tcatacaaca tgcatgttct cctctatctt agaggggtat     7500

tcttcttgaa aataaaaaat attgaaatgc tgtattttta cagctacttt aacctatgat     7560

aattatttac aaaattttaa cactaaccaa acaatgcaga tcttagggat gattaaaggc     7620

agcatttgat gatagcagac attgttacaa ggacatggtg agtctatttt taatgcacca     7680

atcttgttta tagcaaaaat gttttccaat attttaataa agtagttatt ttatagggga     7740

tacttgaaac cagtatttaa gctttaaatg acagtaatat tggcatagaa aaaagtagca     7800

aatgtttact gtatcaattt ctaatgttta ctatatagaa tttcctgtaa tatatttata     7860

tactttttca tgaaaatgga gttatcagtt atctgtttgt tactgcatca tctgtttgta     7920

atcattatct cactttgtaa ataaaaacac accttaaaac atgaacaagc caaaactgtg     7980

tgcagacaaa aaaaaaaaaa                                                 8000


<210>  1050
<211>  8588
<212>  DNA
<213>  homo sapiens

<400>  1050
gagtagctcc agcggccacg ctgaggcgag ggtgacacac catgctcacg gcccctggag       60

accgtcgtgc tggcgagccg tgctccgtag ctccccggtc cgcctcggca gcggtcagag      120

tcgcctacag gagttgagcc gcccgcgcca gaaggttttg gcgaagctct tggagaggcg      180

tcgagcacag tagggcggcg ggggtgcgtt gagcgctcgg gggtcaggca gtcggccggg      240

atcgccgctg gggagcgttt ccgaggcgag gaggaggagg aggagatgct gctcctcttc      300

tccccctccc caggctcctt ctacagctcc ttcagcccac gcccgcagcc gcttgtggga      360

gaagtggtgg tggctctcgg cgcccgcggc ggctgccggc ggcccgcccc gacgccgcgt      420

ccctgcagcc ctcgcccggc gctccagtag caggacccgg tctcgggacc agccggtaat      480

atgcacgtgt cactagctga ggccctggag gttcggggtg gaccacttca ggaggaagaa      540

atatgggctg tattaaatca aagtgctgaa agtctccaag aattattcag aaaagtaagc      600

ctagctgatc ctgctgccct tggcttcatc atttctccat ggtctctgct gttgctgcca      660

tctggtagtg tgtcatttac agatgaaaat atttccaatc aggatcttcg agcattcact      720

gcaccagagg ttcttcaaaa tcagtcacta acttctctct cagatgttga aaagatccac      780

atttattctc ttggaatgac actgtattgg ggggctgatt atgaagtgcc tcagagccaa      840

cctattaagc ttggagatca tctcaacagc atactgcttg gaatgtgtga ggatgttatt      900

tacgctcgag tttctgttcg gactgtgctg gatgcttgca gtgcccacat taggaatagc      960

aattgtgcac cctcattttc ctacgtgaaa cacttggtaa aactggttct gggaaatctt     1020

tctgggacag atcagctttc ctgtaacagt gaacaaaagc ctgatcgaag ccaggctatt     1080

cgagatcgat tgcgaggaaa aggattacca acaggaagaa gctctacttc tgatgtacta     1140

gacatacaaa agcctccact ctctcatcag acctttctta acaaagggct tagtaaatct     1200

atgggatttc tgtccatcaa agatacacaa gatgagaatt atttcaagga cattttatca     1260

gataattctg gacgtgaaga ttctgaaaat acattctccc cttaccagtt caaaactagt     1320

ggcccagaaa aaaaacccat ccctggcatt gatgtgcttt ctaagaagaa gatctgggct     1380

tcatccatgg acttgctttg tacagctgac agagacttct cttcaggaga gactgccaca     1440

tatcgtcgtt gtcaccctga ggcagtaaca gtgcggactt caactactcc tagaaaaaag     1500

gaggcaagat actcagatgg aagtatagcc ttggatatct ttggccctca gaaaatggat     1560

ccaatatatc acactcgaga attgcccacc tcctcagcaa tatcaagtgc tttggaccga     1620

atccgagaga gacaaaagaa acttcaggtt ctgagggaag ccatgaatgt agaagaacca     1680

gttcgaagat acaaaactta tcatggtgat gtctttagta cctccagtga aagtccatct     1740

attatttcct ctgaatcaga tttcagacaa gtgagaagaa gtgaagcctc aaagaggttt     1800

gaatccagca gtggtctccc aggggtagat gaaaccttaa gtcaaggcca gtcacagaga     1860

ccgagcagac aatatgaaac accctttgaa ggcaacttaa ttaatcaaga gatcatgcta     1920

aaacggcaag aggaagaact gatgcagcta caagccaaaa tggcccttag acagtctcgg     1980

ttgagcctat atccaggaga cacaatcaaa gcgtccatgc ttgacatcac cagggatccg     2040

ttaagagaaa ttgccctaga aacagccatg actcaaagaa aactgaggaa tttctttggc     2100

cctgagtttg tgaaaatgac aattgaacca tttatatctt tggatttgcc acggtctatt     2160

cttactaaga aagggaagaa tgaggataac cgaaggaaag taaacataat gcttctgaac     2220

gggcaaagac tggaactgac ctgtgatacc aaaactatat gtaaagatgt gtttgatatg     2280

gttgtggcac atattggctt agtagagcat catttgtttg ctttagctac cctcaaagat     2340

aatgaatatt tctttgttga tcctgactta aaattaacca aagtggcccc agagggatgg     2400

aaagaagaac caaagaaaaa gaccaaagcc actgttaatt ttactttgtt tttcagaatt     2460

aaatttttta tggatgatgt tagtctaata caacatactc tgacgtgtca tcagtattac     2520

cttcagcttc gaaaagatat tttggaggaa aggatgcact gtgatgatga gacttcctta     2580

ttgctggcat ccttggctct ccaggctgag tatggagatt atcaaccaga ggttcatggt     2640

gtgtcttact ttagaatgga gcactatttg cccgccagag tgatggagaa acttgattta     2700

tcctatatca aagaagagtt acccaaattg cataatacct atgtgggagc ttctgaaaaa     2760

gagacagagt tagaattttt aaaggtctgc caaagactga cagaatatgg agttcatttt     2820

caccgagtgc accctgagaa gaagtcacaa acaggaatat tgcttggagt ctgttctaaa     2880

ggtgtccttg tgtttgaagt tcacaatgga gtgcgcacat tggtccttcg ctttccatgg     2940

agggaaacca agaaaatatc tttttctaaa aagaaaatca cattgcaaaa tacatcagat     3000

ggaataaaac atggcttcca gacagacaac agtaagatat gccagtacct gctgcacctc     3060

tgctcttacc agcataagtt ccagctacag atgagagcaa gacagagcaa ccaagatgcc     3120

caagatattg agagagcttc gtttaggagc ctgaatctcc aagcagagtc tgttagagga     3180

tttaatatgg gacgagcaat cagcactggc agtctggcca gcagcaccct caacaaactt     3240

gctgttcgac ctttatcagt tcaagctgag attctgaaga ggctatcctg ctcagagctg     3300

tcgctttacc agccattgca aaacagttca aaagagaaga atgacaaagc ttcatgggag     3360

gaaaagccta gagagatgag taaatcatac catgatctca gtcaggcctc tctctatcca     3420

catcggaaaa atgtcattgt taacatggaa cccccaccac aaaccgttgc agagttggtg     3480

ggaaaacctt ctcaccagat gtcaagatct gatgcagaat ctttggcagg agtgacaaaa     3540

cttaataatt caaagtctgt tgcgagttta aatagaagtc ctgaaaggag gaaacatgaa     3600

tcagactcct catccattga agaccctggg caagcatatg ttctaggaat gactatgcat     3660

agttctggaa actcttcatc ccaagtaccc ttaaaagaaa atgatgtgct acacaaaaga     3720

tggagcatag tatcttcacc agaaagggag atcaccttag tgaacctgaa aaaagatgca     3780

aagtatggct tgggatttca aattattggt ggggagaaga tgggaagact ggacctaggc     3840

atatttatca gttcagttgc ccctggagga ccagctgact tggatggatg cttgaagcca     3900

ggagaccgtt tgatatctgt gaatagtgtg agtctggagg gagtcagcca ccatgctgca     3960

attgaaattt tgcaaaatgc acctgaagat gtgacacttg ttatctctca gccaaaagaa     4020

aagatatcca aagtgccttc tactcctgtg catctcacca atgagatgaa aaactacatg     4080

aagaaatctt cctacatgca agacagtgct atagattctt cttccaagga tcaccactgg     4140

tcacgtggta ccctgaggca catctcggag aactcctttg ggccatctgg gggcctgcgg     4200

gaaggaagcc tgagttctca agattccagg actgagagtg ccagcttgtc tcaaagccag     4260

gtcaatggtt tctttgccag ccatttaggt gaccaaacct ggcaggaatc acagcatggc     4320

agcccttccc catctgtaat atccaaagcc accgagaaag agactttcac tgatagtaac     4380

caaagcaaaa ctaaaaagcc aggcatttct gatgtaactg attactcaga ccgtggagat     4440

tcagacatgg atgaagccac ttactccagc agtcaggatc atcaaacacc aaaacaggaa     4500

tcttcctctt cagtgaatac atccaacaag atgaatttta aaactttttc ttcatcacct     4560

cctaagcctg gagatatctt tgaggttgaa ctggctaaaa atgataacag cttggggata     4620

agtgtcacgg tactgtttga caagggaggt gtgaatacga gtgtcagaca tggtggcatt     4680

tatgtgaaag ctgttattcc ccagggagca gcagagtctg atggtagaat tcacaaaggt     4740

gatcgcgtcc tagctgtcaa tggagttagt ctagaaggag ccacccataa gcaagctgtg     4800

gaaacactga gaaatacagg acaggtggtt catctgttat tagaaaaggg acaatctcca     4860

acatctaaag aacatgtccc ggtaacccca cagtgtaccc tttcagatca gaatgcccaa     4920

ggtcaaggcc cagaaaaagt gaagaaaaca actcaggtca aagactacag ctttgtcact     4980

gaagaaaata catttgaggt aaaattattt aaaaatagct caggtctagg attcagtttt     5040

tctcgagaag ataatcttat accggagcaa attaatgcca gcatagtaag ggttaaaaag     5100

ctctttcctg gacagccagc agcagaaagt ggaaaaattg atgtaggaga tgttatcttg     5160

aaagtgaatg gagcctcttt gaaaggacta tctcagcagg aagtcatatc tgctctcagg     5220

ggaactgctc cagaagtatt cttgcttctc tgcagacctc cacctggtgt gctaccggaa     5280

attgatactg cgcttttgac cccacttcag tctccagcac aagtacttcc aaacagcagt     5340

aaagactctt ctcagccatc atgtgtggag caaagcacca gctcagatga aaatgaaatg     5400

tcagacaaaa gcaaaaaaca gtgcaagtcc ccatccagaa gagacagtta cagtgacagc     5460

agtgggagtg gagaagatga cttagtgaca gctccagcaa acatatcaaa ttcgacctgg     5520

agttcagctt tgcatcagac tctaagcaac atggtatcac aggcacagag tcatcatgaa     5580

gcacccaaga gtcaagaaga taccatttgt accatgtttt actatcctca gaaaattccc     5640

aataaaccag agtttgagga cagtaatcct tcccctctac caccggatat ggctcctggg     5700

cagagttatc aaccccaatc agaatctgct tcctctagtt cgatggataa gtatcatata     5760

catcacattt ctgaaccaac tagacaagaa aactggacac ctttgaaaaa tgacttggaa     5820

aatcaccttg aagactttga actggaagta gaactcctca ttaccctaat taaatcagaa     5880

aaaggaagcc tgggttttac agtaaccaaa ggcaatcaga gaattggttg ttatgttcat     5940

gatgtcatac aggatccagc caaaagtgat ggaaggctaa aacctgggga ccggctcata     6000

aaggttaatg atacagatgt tactaatatg actcatacag atgcagttaa tctgctccgg     6060

gctgcatcca aaacagtcag attagttatt ggacgagttc tagaattacc cagaatacca     6120

atgttgcctc atttgctacc ggacataaca ctaacgtgca acaaagagga gttgggtttt     6180

tccttatgtg gaggtcatga cagcctttat caagtggtat atattagtga tattaatcca     6240

aggtccgtcg cagccattga gggtaatctc cagctattag atgtcatcca ttatgtgaac     6300

ggagtcagca cacaaggaat gaccttggag gaagttaaca gagcattaga catgtcactt     6360

ccttcattgg tattgaaagc aacaagaaat gatcttccag tggtccccag ctcaaagagg     6420

tctgctgttt cagctccaaa gtcaaccaaa ggcaatggtt cctacagtgt ggggtcttgc     6480

agccagcctg ccctcactcc taatgattca ttctccacgg ttgctgggga agaaataaat     6540

gaaatatcgt accccaaagg aaaatgttct acttatcaga taaagggatc accaaacttg     6600

actctgccca aagaatctta tatacaagaa gatgacattt atgatgattc ccaagaagct     6660

gaagttatcc agtctctgct ggatgttgtg gatgaggaag cccagaatct tttaaacgaa     6720

aataatgcag caggatactc ctgtggtcca ggtacattaa agatgaatgg gaagttatca     6780

gaagagagaa cagaagatac agactgcgat ggttcacctt tacctgagta ttttactgag     6840

gccaccaaaa tgaatggctg tgaagaatat tgtgaagaaa aagtaaaaag tgaaagctta     6900

attcagaagc cacaagaaaa gaagactgat gatgatgaaa taacatgggg aaatgatgag     6960

ttgccaatag agagaacaaa ccatgaagat tctgataaag atcattcctt tctgacaaac     7020

gatgagctcg ctgtactccc tgtcgtcaaa gtgcttccct ctggtaaata cacgggtgcc     7080

aacttaaaat cagtcattcg agtcctgcgg ggtttgctag atcaaggaat tccttctaag     7140

gagctggaga atcttcaaga attaaaacct ttggatcagt gtctaattgg gcaaactaag     7200

gaaaacagaa ggaagaacag atataaaaat atacttccct atgatgctac aagagtgcct     7260

cttggagatg aaggtggcta tatcaatgcc agcttcatta agataccagt tgggaaagaa     7320

gagttcgttt acattgcctg ccaaggacca ctgcctacaa ctgttggaga cttctggcag     7380

atgatttggg agcaaaaatc cacagtgata gccatgatga ctcaagaagt agaaggagaa     7440

aaaatcaaat gccagcgcta ttggcccaac atcctaggca aaacaacaat ggtcagcaac     7500

agacttcgac tggctcttgt gagaatgcag cagctgaagg gctttgtggt gagggcaatg     7560

acccttgaag atattcagac cagagaggtg cgccatattt ctcatctgaa tttcactgcc     7620

tggccagacc atgatacacc ttctcaacca gatgatctgc ttacttttat ctcctacatg     7680

agacacatcc acagatcagg cccaatcatt acgcactgca gtgctggcat tggacgttca     7740

gggaccctga tttgcataga tgtggttctg ggattaatca gtcaggatct tgattttgac     7800

atctctgatt tggtgcgctg catgagacta caaagacacg gaatggttca gacagaggat     7860

caatatattt tctgctatca agtcatcctt tatgtcctga cacgtcttca agcagaagaa     7920

gagcaaaaac agcagcctca gcttctgaag tgacatgaaa agagcctctg gatgcatttc     7980

catttctctc cttaacctcc agcagactcc tgctctctat ccaaaataaa gatcacagag     8040

cagcaagttc atacaacatg catgttctcc tctatcttag aggggtattc ttcttgaaaa     8100

taaaaaatat tgaaatgctg tatttttaca gctactttaa cctatgataa ttatttacaa     8160

aattttaaca ctaaccaaac aatgcagatc ttagggatga ttaaaggcag catttgatga     8220

tagcagacat tgttacaagg acatggtgag tctattttta atgcaccaat cttgtttata     8280

gcaaaaatgt tttccaatat tttaataaag tagttatttt ataggggata cttgaaacca     8340

gtatttaagc tttaaatgac agtaatattg gcatagaaaa aagtagcaaa tgtttactgt     8400

atcaatttct aatgtttact atatagaatt tcctgtaata tatttatata ctttttcatg     8460

aaaatggagt tatcagttat ctgtttgtta ctgcatcatc tgtttgtaat cattatctca     8520

ctttgtaaat aaaaacacac cttaaaacat gaacaagcca aaactgtgtg cagacaaaaa     8580

aaaaaaaa                                                              8588


<210>  1051
<211>  5742
<212>  DNA
<213>  homo sapiens

<400>  1051
gttttagcgg ggactacgat ccaggctgga gttgcgctcg gccggtctga gcgctggcgc       60

tgcccggacg ccgcggggtc cccgccagcc cagggcactc ggcgcgggga tctgcgcgcc      120

tcgctctccc ttcccgatgc cgccgcccgg ctgctgatcg ccgcaccacc ttccctcatc      180

ggcttgggtc cgtggaggtc cctgcagagg caggaagcct ccttaggaaa gcagggatgg      240

aggtaaattg tttaacacta aaagacctga tcagccccag gcagcccaga ctagattttg      300

cagttgaaga tggggaaaat gcacaaaagg aaaatatatt tgttgatcga tcaaggatgg      360

ccccgaagac tccaataaaa aatgaaccaa ttgatttatc gaagcaaaaa aaatttactc      420

cagaaagaaa tcccattact ccagttaagt ttgttgacag acagcaagcg gaaccatgga      480

cacccacagc taacctgaag atgctcatta gtgctgccag cccagatata agggaccggg      540

agaagaaaaa gggactattc cgacccattg aaaacaagga cgatgcattt acagattctc      600

tacagcttga tgttgttggg gacagtgctg tggacgaatt tgaaaagcaa aggccaagca      660

gaaaacagaa aagtttagga ctcctgtgcc agaagtttct agctcgctat ccaagttatc      720

ccttgtcaac tgagaaaact accatctccc tagatgaagt tgctgtcagt cttggtgtgg      780

aaaggagacg catctatgac attgtaaatg tgctggagtc gctgcatctg gtcagccggg      840

tggctaagaa tcagtatggc tggcatggac ggcacagcct gccaaaaacc ctgaggaacc      900

tccagagact aggagaggag cagaaatatg aagagcaaat ggcctacctc caacagaaag      960

agctggacct gatagattat aaatttggag aacgtaaaaa agatggtgat ccagattccc     1020

aggaacaaca gttactggat ttctctgaac ccgactgtcc ctcttcatct gcaaacagta     1080

gaaaagacaa gtctctgaga attatgagcc agaagtttgt catgctgttc ctcgtctcca     1140

aaaccaagat tgtcactctg gatgtggctg ccaaaatact gatagaagaa agccaagatg     1200

ccccagacca tagtaaattt aaaacaaagg tacgacgcct ctatgacata gccaatgttc     1260

tgaccagctt ggctctgata aagaaagtgc atgtaacaga agagcgaggt cgtaaaccag     1320

ccttcaagtg gatcgggcct gtggacttca gctcaagtga tgaagaactg gtggatgttt     1380

ctgcatctgt cttaccagaa ttgaaaagag aaacatatgg ccagattcaa gtctgtgcaa     1440

aacagaagct ggctcgccat ggttctttta acacagttca ggcttctgag aggatccaga     1500

ggaaagtgaa ctcagaaccg agcagcccgt acagagaaga acaaggatca ggtggctact     1560

ctttagaaat tggaagcctg gcagctgtct atagacagaa aatagaagac aattcacagg     1620

gaaaagcctt tgccagtaag agagtggtgc ctccatcaag cagcttggac cctgttgctc     1680

ctttccctgt cctctctgtt gacccagaat attgtgttaa tcctttagcc cacccagtat     1740

tttctgttgc tcagacggac ctgcaggcat tctccatgca gaacggtctg aatggacaag     1800

tggatgtctc acttgcttct gcagcctctg ctgtggagag cctgaagcca gcactccttg     1860

ctggccagcc tctagtgtat gtgccctctg cctcactgtt catgctgtat ggaagtctgc     1920

aggagggacc agcgtcaggg tcagggtcag agagggatga cagaagctca gaagccccag     1980

ccacagtaga gctgtcatct gcaccctcag ctcagaagcg cctctgtgag gagaggaaac     2040

ctcaggagga ggatgagcca gccactaaaa ggcaaagtag ggaatatgaa gacggcccgc     2100

tgtcgcttgt catgcccaag aaaccctcag attccacaga ccttgcctct cccaagacta     2160

tgggtaacag ggcatctata cccctcaaag acattcatgt gaatggccaa ctccctgctg     2220

cagaagagat ttcaggaaag gcaacagcaa actctcttgt ttcttctgag tggggaaatc     2280

cttcaagaaa tacagatgtt gaaaagcctt caaaagaaaa tgaaagcacc aaagagcctt     2340

ctttgctaca atatctttgt gtgcagtctc ctgcaggatt aaatggtttc aatgtacttt     2400

tatctggcag tcaaaccccc cctactgtgg gcccgtcctc aggtcagctg ccgtctttca     2460

gtgtcccttg catggtctta ccatctccac ctctgggccc ttttcctgtt ctctattctc     2520

ctgcaatgcc gggcccggtt tcttctactc ttggtgctct cccaaacaca ggacctgtga     2580

atttcagctt gcctggcctt ggatcaatag cccagcttct cgtcggcccc acagctgtgg     2640

ttaatccaaa gtcgtccaca ctcccttctg cagaccctca gcttcagagt cagccctcac     2700

taaacctaag tccagtgatg tcaaggtcac acagtgtcgt ccaacaacct gagtcccccg     2760

tttacgtggg acatccagtc tcagtagtaa aattacatca gtcaccagtt ccagtgaccc     2820

ccaagagcat ccaacgcaca catcgtgaga cgtttttcaa gacacccggc agccttggag     2880

accctgtcct gaagagaaga gaaaggaacc agtcacgaaa caccagctcg gcccagagga     2940

gactagaaat ccccagcggc ggcgctgact aacctgccgc tttgccaggt gggggtggga     3000

tcaaacgccc tgagagtccc ggatgtccga ggcgggatgc aaaccatccc gtcctgagca     3060

cgggtccttc ctctctcttt catccacact tctgttaact tcccaccacc atcaatcatc     3120

tgatttcctg aaagtaatta attgtgcatt taataccagt tagagttccg actctgcatg     3180

gtgtcacagt gaaagcgccg actgacttat ggttttgatt caagaatcgt cttattctgg     3240

aagtagatct gaataggcta ccggagcctt gtttttctaa aggggggcgc tgtctagcac     3300

ttaactaggg taagcattct taacatgtat ttccacttgc cctgagtaaa tctgtggtga     3360

gagaagcttc ctttctgcag tttaaaaaag ctactgcttc cttaggcttc atcaggaagc     3420

caccttcagt tgtgaatcct atggtgttat ttattttgtt cctgaaatgg gatttagtgc     3480

aaaaagttta caactacagt ctttaacaca tttttttcag ggtatgacga cttgaatgtt     3540

tatactttta ttctataatt tgccctgcac ttattttaca acctagtaat aatgtggata     3600

aatgtatcta catgacacat gtcaagacca aaataactgt gaatgacaca ccttgctgta     3660

aatgaactgt gctaaccctg actgtgggct tgagaacaaa gatgaactct agaactctag     3720

cagcctaact gctgcttctc aaataactgt gtgaacagtg agatattact gtttgtttct     3780

aaaaatccta ctgtgcccag tttccttcac tacatgccct gcatttttta tttaaatatt     3840

tagctgtagc gccatcagat atggatgcct tctaacaatt gctgtttgta aaataaatca     3900

ggatggtaga aagtgattat atggaaaatt ggaacctgga tgagaccttt tcgttgaatt     3960

ctgaagagta atgatgtgaa aattgataca gggcaagaga tgattctttt gtttttcttc     4020

tacttcatgt ccagaagagt aagagggaaa atggacatat gtttcatatc caagggtatt     4080

caaactgtag ttagttggta cctctgaaaa atgagaatgg tgagcgcacg ggttggttgt     4140

tctagcatga atacaattct ggaaactgtt atgcaatttc ccttttttaa cccacattac     4200

tttaggggtg cattaagtcg ccaaactata ctagttcttt gtattcctag acttgctgat     4260

atttacctct ctcttgtctc ttcagagtaa atggttccct tctttccttc ctactttcct     4320

tcattctctc ttccttccct ccttcctact tcttttcttc cttcctcttc ctctcttaaa     4380

actatcttag atgtagaatc ctggtgtagg gttttatttt atttttattt tttgacccaa     4440

taaaatgtta tatgaaagaa tgaaaatatt aatttaagag actctgggag tctgaataaa     4500

gtagctttat attaactaca ggataatatt agccttatta cccccacaag attttttaaa     4560

acttgaggta ggtagctaca ttaaataaat ttgctactta tataaaaatt tttatcaaca     4620

ctaaactttt aaagtttaca agtttttttt ttctttttta cagtcttcta tagagttagg     4680

ttaaaaatgt ggttctaacc atcaacaatt gcatggttaa atgaccctga actaaaactg     4740

atgggttccc tatcaaaaca aataaaaata tacctttttc aggtttcaat ctgtgcaggg     4800

tatatgcatg ttaattctac catgcttaag aacttccaca aaatatttca tggagaggtc     4860

tgcatttaga cggaaacaga aattgctttt cccctcactg ttcctgaatg ctctatactt     4920

gttttaacat ttttgctatc tttttttatt attctgatca tgatatgacc atttaacctc     4980

agaattcata attcctgagg ggtgttaaga agcagtccca ttggtgagga tattatgact     5040

tggtgaccat tcttaggagt agaaaaccaa ggacaattgc ttctgtattc agtatccact     5100

tcttaatgtg gctttatatg taaaaataat aatgcagtgg ttgtttctgt caggaaaata     5160

aatcttacag aacaactggt ggaattgaag ctgctgcgct agacttggat attttgggta     5220

gtgaagaagc aatggcaatc ttgagtctat tattgtataa tttagtaaaa gaaaaaaata     5280

atcgttggtg gtcctactaa gagaatgcag cttttttgag ttgtcacaga ggctgtgtgt     5340

gccctacact gaccagggtt tgtaaaaccc tttcattctg gtacaagagt cgggggtata     5400

acttttatac ttgaatctac ctaccaagtt tacatttctc aattcctttt tgtaaggtgc     5460

tatttctgta tttaaataac tttcttttaa cgtaaagctg ctttctgctt atcttattgc     5520

actgctagtt gtatgtaggt attaatttta ttgctgctta ctgcttttgt tttcttatta     5580

tttagctctg ctctttttcc taatggctat attatctata gctatttact tgtaactgta     5640

ctacatgtaa actgattttt tgttctgatt ttttttctaa tatttttagg aaaatattaa     5700

gctttataaa atagcaataa aaaataattc atttaagaag aa                        5742


<210>  1052
<211>  5519
<212>  DNA
<213>  homo sapiens

<400>  1052
gtaatgctga gacagactcc cagaagatct gagcgagtcg cgtagctgag cccggcaggg       60

gctggggtgg tgctgctgct atgagctgca ccatcgagaa gatcctgaca gacgccaaga      120

cgctgctgga gaggctacgg gagcacgatg cggccgccga gtcgctggtg gatcagtcgg      180

cggcgctgca ccggcgggta gcagctatgc gggaggcggg gacagcgctt ccggaccagg      240

tcaggcagag gtatcaagag gatgcatccg atatgaagga catgtccaaa tacaaacctc      300

acattctgct gtcccaagag aacacacaga ttagagactt gcaacaggaa aacagagagc      360

tatggatttc cttggaggaa caccaggatg ctttggaact tatcatgagc aaatatcgga      420

aacagatgtt acagttaatg gttgctaaaa aagcggtgga tgctgaacca gtcctgaaag      480

ctcaccagtc tcactctgca gaaattgaga gtcagattga cagaatctgt gaaatgggag      540

aagtgatgag gaaagcagtt caggtggatg atgaccagtt ttgtaagatt caggaaaaat      600

tagcccaatt agagcttgaa aataaggaac ttcgagaatt attgtccatc agcagtgagt      660

ctcttcaagc cagaaaggaa aactcaatgg acactgcttc ccaagccatc aaataactga      720

actctgaatg atggctggag attgtctatc aaggaaggaa gttactgtct tcccattcaa      780

gtactgtcca ttaagtgtct tgcctcagat ttgatttaat cttaattaaa ggtatcaggt      840

ggcaatttag aattccagtc aatattggct gtccacagtt ctcagatgtg ttaatgtgaa      900

tactacatgc tgaatttcac cattcctttc tcaaagagac tacttttaat tttcatttct      960

gggaccttga tttatataaa ctatgttttc agttctttgt tatttttcac atctctgaaa     1020

ctttgagcat tttttataag ccagcaattt attttacata gcattgtaaa atacacttct     1080

aggaaatttt aggaaagatt taactgttta aatctatttg gcataaacct tgattttttt     1140

tttccatttg acaaaaataa tacaattcca cagaactaga tcagcagatt ctctgatttg     1200

taatgtcatt cacctgtgac attttaagtc tctctggtgc taagaattgg cactttatag     1260

cctggtgcct ttacttttaa tttgagagaa cctactgcta gtcccaggaa acacacttgg     1320

aaataagtca gctatttttt ttgcccagtg atgctatagt tgtcatattg tccaaagttc     1380

atattgttca aagctgagga gcttgtcctg tgtatgtgaa tgcacacatg tgcacttagt     1440

tcaaatacta aaagtagctt ttattaaata taatcagcca aaaacacaca caaaataaaa     1500

aaaacaaata taagtagtca gtttttcaat gttatcctac tagttctaca ttctatttta     1560

atttttatac aatttccatt ttatagttaa gaaccatcac ttacttggat tggatgtctt     1620

tcattcctag cactaatagt tggctttctt tttttttgtt tacatagaag cagggttttt     1680

ttttatcttt tttctttttt tttgtttaag ctatataaaa aggtgaggaa gcagttttgt     1740

tacctaatga aaattattac actcataatg ctgtgtaggc aacattgaga ttcaaatgcc     1800

cagtggtcaa ctgggttcac tcatcaactc attcccgtcc cagtttactc acatttcaaa     1860

tttataaatt tcttcatgtt atactattct atttagattt gcccagaatt agttgaaata     1920

atgctaaacc tgtcaatatt ttccagtaac attaagcacc atactgcatg ggagagacac     1980

agtactaaaa agagttgtta gtgctttatg tgagtgatat ttctttcgta atgctataaa     2040

gaactacagt taaaataaca aaatatttta aagatgtcct aaaagcatct gatcccagta     2100

ataactaatg gatgtcatct agagcagtgg gtgttaatga ataggtatat gtcatttaag     2160

aatttttcaa atttctgttt gatatcctgc atagaatttg acaaaaaaaa cacttccaag     2220

tgtgagcatt ttttatttca tttcccaaga gtaagtaagt aactattagc ccagccatct     2280

gcctcgaagt ataccttaag tgaccccata aatccattca agaggcaggt actctatacc     2340

atttggcagc cacggccaaa cctaccatgg ccagatttca gtgaaaatga tgaagtaatc     2400

aaatcaaggt ataatatggt gtccctttat gtgctttatg ttcctttaga gctgtttata     2460

aagttcttta tatctcaagt gttaggataa atcgacatac taacttttcc ccctgcaaaa     2520

ttaaaagcct gaggtacaag tctaagaagc ttttagtgct ctacataata taaattctgg     2580

ctggtgttaa tgctatgaag ataatatgta gttagaaaat tgagtcgggg aggaatgctc     2640

ttcattttaa gtggatttta aagtttctcc ttgagtggat gaagaacttg cctggtttgc     2700

aaaaatctta gttcaaaatt atattttcta acaaaaactg cattttgaga agataagcta     2760

attttactca gtagtaagtc aaatgaggaa gtgcagaggg tttttttaca tatatatagc     2820

aaccttgtca agtggtcctc acaagagtca taaatacttt gtaattagca cagtatattc     2880

agcagtgtat aactctacaa atagtacctt atattagtgt agtattatat caatatctta     2940

tgtataattc ttatattaat accttatgca taattggatt caaacattga aggtctattt     3000

tagtgttctt caaaatgtgc ttccctgacc tactgaaata gaaacttggt gatgaagttc     3060

aagaatttgt attctaatca tctcaaacaa ttcctaaaga cactgatttt aaaatatcta     3120

gtctaggccc cattgtgtaa tagttagcac tctaaaagat gaaaaagaaa atagtctatg     3180

tgccaaccac ttcattagta cttatgaatt taaaaatgaa aaagtctggt acaggagaca     3240

agtatatata taaaattata atgcagtgtg ataaatccat tatagtatgt ataagataca     3300

gaagagggac tttaaacttg agaattcaat agagataata aatgggtagg agggaaatag     3360

aaaactttgg tgccacaaaa gcaaagtatg tatggtattg ccaataatag ctaccatcta     3420

ttgagtgctt tactacctgt caggtactgt attatataaa ctccatttta actgtacctc     3480

attttgcaga tactcaggca caaggaggtg gttatttgtc caaactggaa ccaagattca     3540

aacccagaca gagtcttaag cacattttta atcactaact aacttgagat gcctaaatgc     3600

caaatactgt tgggagttca agtggttctt gattagcaaa atctattttt attagtgcaa     3660

aagaaacacc acagcttata aagtattatg aattcaataa atggagtctt aactaatgag     3720

atattatttt ctagaatggt gtagctgaga gtatgtgtga ttcaactgaa aggaataatg     3780

tttaatcagt gactcttact atatacagga aaaggtgcag ttctgtcttt caaatctgcc     3840

tccttaccat attggcttac atccctcatg ctgttttctt gtgtttgcta gaaagttgtt     3900

gccaagccaa atgtcatggc catgttgaag gcaaggaaga aaaaatggaa atggcctgtg     3960

ccagctatat atatcgcctt ttatgaggga aagcaaagct ttctcagaaa tcccaaatgg     4020

attttccctt gacttaattg cctgaccagt taaatggcca ctggtacctg caaagaaagc     4080

agggtacata gctgtcccaa ataaaatcag tattagcaag aagaaagaat attgagaaag     4140

caattaacag tgtctgtgac tgtgacatgt ctgtgacttt atattgtcaa gtcctttccc     4200

cttgaatata gttttggaag aattagctga aggagtgtgt tgacattgaa tggccaagag     4260

aatgggctgt agcagacatc tgtcatttct cttttggctg cccagtatcc taactcctgt     4320

gtttaaggaa tccctcacct aatgaggcag agcatttctt cctcctaaag aatttgaaag     4380

taccaggtaa tgttttctca gcctcctttt gcagctaagg aagaaacatc tgccttcaat     4440

tttaaaatta gtgatacaaa gaaggaggga accatgcaga ttcctttgaa gatggtgatt     4500

aacaacacta ctgcattcat ctccacagag gtacagcaaa agtgatttag ttagcgataa     4560

cctctaattc tattttttta tttttatttt ttgagacagt cttgctctgt caaccaggct     4620

ggagtgcagt agcactgtct taactcactg caacctccac ctcctgggtt caagcgattc     4680

tcctgcctca gcctcccaag tcgctgggat tacaagtgcc caccaccatg cacagctaat     4740

ttttgtgttt ttagtagatg gggtttctcc atgttggcca ggctggtctc gaacttatga     4800

cttcaggtga tccgcccgcc ttggcctccc aaagtgctgg gattataggc gtgagccact     4860

gtgcctggcc tgtaacctct aattcttgtt tgctggctgt cctagagatc ctgagaatta     4920

cttttaataa aatcattttt ttgctgttat taaaactaac ctgaattgcc taaaaccaag     4980

aactctgctt gataaaataa gcatagtttt aggaacagcc atgcagatat aaattttatc     5040

aacactttat acataatttg ggacttatat ttaaatgtaa tatttgatgc ttataaaagg     5100

gtaaatgggg aatgcaaata aattatcaag cataataact catcacctaa cttaagaata     5160

acattatgag tgcttgtatt ttatctattt gagctcttct cctatctttg ccgacccccc     5220

cgctctcttt ttaatagatt tgttcgaatg tagaaagacc taaaatacat atgtatccct     5280

aaagtgactt attttatagt tttctttctt tttgaacttc aaaaaaattg tatcatactc     5340

tatgtagtct aaggatttgg tttttttcac tcaacatgtc tctagaattc acaagtttta     5400

ttgttttata gctgtcattt tcattgatgt atatttcatt gttgggttat acaacatatt     5460

gttaaggaat acatacatat ataataaatt atacattttt taaaaaaaaa aaaaaaaaa      5519


<210>  1053
<211>  2303
<212>  DNA
<213>  homo sapiens

<400>  1053
gaattcgtcc aaactgagga tcacaagtct ccacattctg agtaggagga tgagggtctg       60

agttaggatt tgggtcctgc agggcttgct aaggaatccc ctgatggcct aggattccac      120

gcagagcaca tctggtgtga gagagctcgc tgcaagggtg aaggctccgc cctatcagat      180

agacaaccag gccaccaaga ggcccagccc tccaaaccct ggatttgcaa catcctcaaa      240

gaacagcaac gggccttgag cagaattgag aaggaaatac ccccacctgc cctcagccgt      300

taagtgggct ttgctattca caagggcctc tgggtgtcct ggcagagagg ggagatggca      360

caggcaccag gtgctagggt gccagggcct cccgagaagg aacaggtgca aagcaggcaa      420

ttagcccaga aggtatccgt ggggcaggca gcctagatct gatgggggaa gccaccagga      480

ttacatcatc tgctgtaaca actgctctga aaagaagata tttttcaacc tgaacttgca      540

gtagctagtg gagaggcagg aaaaaggaaa tgaaaccaga gacagaggga agctgagcga      600

aaatagacct tcccgagaga ggaggaagcc cggagagaga cgcacggtcc cctccccgcc      660

cctaggccgc cgccccctct ctgccctcgg cggcgagcag cgcgccgcga cccgggccga      720

aggtgcgagg ggctccgggc ggccgggcgg gcgcacacca tccccgcggg cggcgcggag      780

ccggcgacag cgcgcgagag ggaccgggcg gtggcggcgg cgggaccggg atggaaggga      840

gcgcggtgac tgtccttgag cgcggagggg cgagctcgcc ggcggagcgc cggagcaagc      900

ggaggcgcag gagcggcggc gacggcggcg gcggcggcgg cgcccgagca cccgaggggg      960

tccgagcccc ggcagccggc cagccccgcg ccacaaaggg agcgcccccg ccgcccggca     1020

ccccgcctcc ctccccaatg tcctcggcca tcgaaaggaa gagcctggac ccttcagagg     1080

aaccagtgga tgaggtgctg cagatccccc catccctgct gacatgcggc ggctgccagc     1140

agaacattgg ggaccgctac ttcctgaagg ccatcgacca gtactggcac gaggactgcc     1200

tgagctgcga cctctgtggc tgccggctgg gtgaggtggg gcggcgcctc tactacaaac     1260

tgggccggaa gctctgccgg agagactatc tcaggctttt tgggcaagac ggtctctgcg     1320

catcctgtga caagcggatt cgtgcctatg agatgacaat gcgggtgaaa gacaaagtgt     1380

atcacctgga atgtttcaaa tgcgccgcct gtcagaagca tttctgtgta ggtgacagat     1440

acctcctcat caactctgac atagtgtgcg aacaggacat ctacgagtgg actaagatca     1500

atgggatgat ataggcccga gtccccgggc atctttgggg aggtgttcac tgaagacgcc     1560

gtctccatgg catcttcgtc ttcactctta ggcactttgg gggtttgagg gtggggtaag     1620

ggatttctta ggggatggta gacctttatt gggtatcaag acatagcatc caagtggcat     1680

aattcagggg ctgacacttc aaggtgacag aaggaccagc ccttgaggga gaacttatgg     1740

ccacagccca tccatagtaa ctgacatgat tagcagaaga aaggaacatt taggggcaag     1800

caggcgctgt gctatcatga tggaatttca tatctacaga tagagagttg ttgtgtacag     1860

acttgttgtg actttgacgc ttgcgaacta gagatgtgca attgatttct tttcttcctg     1920

gctttttaac tcccctgttt caatcactgt cctccacaca agggaaggac agaaaggaga     1980

gtggccattc tttttttctt ggcccccttc ccaaggcctt aagctttgga cccaaggaaa     2040

actgcatgga gacgcatttc ggttgagaat ggaaaccaca acttttaacc aaacaattat     2100

ttaaagcaat gctgatgaat cactgttttt agacaccttc attttgaggg gaggagttcc     2160

acagattgtt tctatacaaa tataaatctt aaaaagttgt tcaactattt tattatccta     2220

gattatatca aagtatttgt cgtgtgtaga aaaaaaaaca gctctgcagg cttaataaaa     2280

atgacagact gaaaaaaaaa aaa                                             2303


<210>  1054
<211>  1605
<212>  DNA
<213>  homo sapiens

<400>  1054
agagggaagc tgagcgaaaa tagaccttcc cgagagagga ggaagcccgg agagagacgc       60

acggtcccct ccccgcccct aggccgccgc cccctctctg ccctcggcgg cgagcagcgc      120

gccgcgaccc gggccgaagg gagcgcggtg actgtccttg agcgcggagg ggcgagctcg      180

ccggcggagc gccggagcaa gcggaggcgc aggagcggcg gcgacggcgg cggcggcggc      240

ggcgcccgag cacccgaggg ggtccgagcc ccggcagccg gccagccccg cgccacaaag      300

ggagcgcccc cgccgcccgg caccccgcct ccctccccaa tgtcctcggc catcgaaagg      360

aagagcctgg acccttcaga ggaaccagtg gatgaggtgc tgcagatccc cccatccctg      420

ctgacatgcg gcggctgcca gcagaacatt ggggaccgct acttcctgaa ggccatcgac      480

cagtactggc acgaggactg cctgagctgc gacctctgtg gctgccggct gggtgaggtg      540

gggcggcgcc tctactacaa actgggccgg aagctctgcc ggagagacta tctcaggctt      600

tttgggcaag acggtctctg cgcatcctgt gacaagcgga ttcgtgccta tgagatgaca      660

atgcgggtga aagacaaagt gtatcacctg gaatgtttca aatgcgccgc ctgtcagaag      720

catttctgtg taggtgacag atacctcctc atcaactctg acatagtgtg cgaacaggac      780

atctacgagt ggactaagat caatgggatg atataggccc gagtccccgg gcatctttgg      840

ggaggtgttc actgaagacg ccgtctccat ggcatcttcg tcttcactct taggcacttt      900

gggggtttga gggtggggta agggatttct taggggatgg tagaccttta ttgggtatca      960

agacatagca tccaagtggc ataattcagg ggctgacact tcaaggtgac agaaggacca     1020

gcccttgagg gagaacttat ggccacagcc catccatagt aactgacatg attagcagaa     1080

gaaaggaaca tttaggggca agcaggcgct gtgctatcat gatggaattt catatctaca     1140

gatagagagt tgttgtgtac agacttgttg tgactttgac gcttgcgaac tagagatgtg     1200

caattgattt cttttcttcc tggcttttta actcccctgt ttcaatcact gtcctccaca     1260

caagggaagg acagaaagga gagtggccat tctttttttc ttggccccct tcccaaggcc     1320

ttaagctttg gacccaagga aaactgcatg gagacgcatt tcggttgaga atggaaacca     1380

caacttttaa ccaaacaatt atttaaagca atgctgatga atcactgttt ttagacacct     1440

tcattttgag gggaggagtt ccacagattg tttctataca aatataaatc ttaaaaagtt     1500

gttcaactat tttattatcc tagattatat caaagtattt gtcgtgtgta gaaaaaaaaa     1560

cagctctgca ggcttaataa aaatgacaga ctgaaaaaaa aaaaa                     1605


<210>  1055
<211>  1705
<212>  DNA
<213>  homo sapiens

<400>  1055
ggtgcgaggg gctccgggcg gccgggcggg cgcacaccat ccccgcgggc ggcgcggagc       60

cggcgacagc gcgcgagagg gaccgggcgg tggcggcggc gggaccggga tggaaggtta      120

agtcctgagc agcagcagca gctgcagccg cctggagcca ggctgcgcgc cccggccccc      180

gcctcggccg cggcgcgccc gcagcccggt gattcgctct ctctctttgg cgtttgaagg      240

gagcgcggtg actgtccttg agcgcggagg ggcgagctcg ccggcggagc gccggagcaa      300

gcggaggcgc aggagcggcg gcgacggcgg cggcggcggc ggcgcccgag cacccgaggg      360

ggtccgagcc ccggcagccg gccagccccg cgccacaaag ggagcgcccc cgccgcccgg      420

caccccgcct ccctccccaa tgtcctcggc catcgaaagg aagagcctgg acccttcaga      480

ggaaccagtg gatgaggtgc tgcagatccc cccatccctg ctgacatgcg gcggctgcca      540

gcagaacatt ggggaccgct acttcctgaa ggccatcgac cagtactggc acgaggactg      600

cctgagctgc gacctctgtg gctgccggct gggtgaggtg gggcggcgcc tctactacaa      660

actgggccgg aagctctgcc ggagagacta tctcaggctt tttgggcaag acggtctctg      720

cgcatcctgt gacaagcgga ttcgtgccta tgagatgaca atgcgggtga aagacaaagt      780

gtatcacctg gaatgtttca aatgcgccgc ctgtcagaag catttctgtg taggtgacag      840

atacctcctc atcaactctg acatagtgtg cgaacaggac atctacgagt ggactaagat      900

caatgggatg atataggccc gagtccccgg gcatctttgg ggaggtgttc actgaagacg      960

ccgtctccat ggcatcttcg tcttcactct taggcacttt gggggtttga gggtggggta     1020

agggatttct taggggatgg tagaccttta ttgggtatca agacatagca tccaagtggc     1080

ataattcagg ggctgacact tcaaggtgac agaaggacca gcccttgagg gagaacttat     1140

ggccacagcc catccatagt aactgacatg attagcagaa gaaaggaaca tttaggggca     1200

agcaggcgct gtgctatcat gatggaattt catatctaca gatagagagt tgttgtgtac     1260

agacttgttg tgactttgac gcttgcgaac tagagatgtg caattgattt cttttcttcc     1320

tggcttttta actcccctgt ttcaatcact gtcctccaca caagggaagg acagaaagga     1380

gagtggccat tctttttttc ttggccccct tcccaaggcc ttaagctttg gacccaagga     1440

aaactgcatg gagacgcatt tcggttgaga atggaaacca caacttttaa ccaaacaatt     1500

atttaaagca atgctgatga atcactgttt ttagacacct tcattttgag gggaggagtt     1560

ccacagattg tttctataca aatataaatc ttaaaaagtt gttcaactat tttattatcc     1620

tagattatat caaagtattt gtcgtgtgta gaaaaaaaaa cagctctgca ggcttaataa     1680

aaatgacaga ctgaaaaaaa aaaaa                                           1705


<210>  1056
<211>  1657
<212>  DNA
<213>  homo sapiens

<400>  1056
cttttgaagt taacaaaaat tgagtccctg gctgggaggt cccccgagtg ttccgctgtg       60

ggctggaggt ggcgtttctg tcgtgattta tgtggagtgg ttcaaaacag aagttaatca      120

ctcgggaagc ggacgggagg ggcggcgcta ctgcgcatgc ccgggagccg cctggagttt      180

ggaactccac attctttcag acccggcccg ctgcggggcg ttcctggggg gtagcctcaa      240

ggccagcggg gttccttcgg ctgcgtttct gtgggaggcc ctgaaacgcg cggagcttcc      300

ctctgcctcc aggctttccc agcgagagtg aaattaaact tgaaactcgg atcaactggc      360

agtcgttgtt ggtattgttg cagcatctgg cagtgagact gaggatgagg acagcatgga      420

cattcccttg gacctttctt catccgctgg ctcaggcaag agaaggagaa ggggcaacct      480

acccaaggag tctgtgcaga ttcttcggga ttggctgtat gagcaccgtt acaatgccta      540

tccttcagag caagaaaaag cgttgctgtc ccagcaaaca cacctgtcta cgctacaggt      600

ctgtaactgg ttcatcaacg cccgccgcag gctcctccct gacatgctga gaaaggatgg      660

caaagatcca aatcagttca caatttcccg ccgtggggcc aagatttctg aaacgagctc      720

tgtggagtcc gtgatgggca tcaaaaactt catgccagct ctagaggaga ccccatttca      780

ttcctgtaca gctgggccaa acccaaccct agggaggcca ctgtctccta agccgtcatc      840

cccgggatca gttttggctc gtccatcagt gatctgccat accactgtga ctgcattgaa      900

agatgtccct ttctctctct gccagtcggt cggtgtggga caaaacacag atatacagca      960

gatagcggcc aaaaacttca cagacacctc tctcatgtac ccagaggaca cttgtaaatc     1020

tggaccaagt acgaatacac agagtggtct tttcaacact cctcccccta ctccaccgga     1080

cctcaaccag gacttcagtg gatttcagct tctagtggat gttgcactca aacgggctgc     1140

agagatggag cttcaggcaa aacttacagc ttaacccatt ttcaagcaaa acagttctca     1200

gaaatgtcat gattgccggg gtgaaggcaa gagatgaatt gcattatttt atatattttt     1260

tattaatatt tgcacatggg attgctaaaa cagcttcctg ttactgagat gtcttcaatg     1320

gaatacagtc attccaagaa ctataaactt aaagctactg tagaaacaaa gggttttctt     1380

ttttaaatgt ttcttggtag attattcata atgtgagatg gttcccaata tcatgtgatt     1440

ttttttttcc tccccttccc tttttttgtt attttttcag actgtgcaat acttagagaa     1500

cctatagcat cttctcattc ccatgtggaa caggatgccc acatactgtc taattaataa     1560

attttccatt ttttttcaaa caagtatgaa tctagttggt tgatgccttt tttttcatga     1620

cataataaag tattttcttt aaaaaaaaaa aaaaaaa                              1657


<210>  1057
<211>  1687
<212>  DNA
<213>  homo sapiens

<400>  1057
gactcccgcc cgcatctcgg ggtgggaagg gttcaggaaa cacagaccag cttatcttaa       60

ggaagcctgg tcgggaatct ttcaaaaaca catctgttac aagggggaaa gacacctcca      120

ggacaacagt gatttgcctc agcggggcaa aggccaggcc tgacggaaga gcccagcctt      180

cgccgagggc cgcagggagc cagagactcg agcctgcggt tccagccccg ccgcggttcc      240

ggccccgccg cgatcccgag gcctgcgcat gctcggtgct gcgcggggct ccctccttac      300

cgcaggagct cctcatcgag aaacccaggt tggtgtcttt tccacgtggt agaagctggc      360

taacctccac ttccacattc cagcccaagg gaaagtccaa ggtattgttg cagcatctgg      420

cagtgagact gaggatgagg acagcatgga cattcccttg gacctttctt catccgctgg      480

ctcaggcaag agaaggagaa ggggcaacct acccaaggag tctgtgcaga ttcttcggga      540

ttggctgtat gagcaccgtt acaatgccta tccttcagag caagaaaaag cgttgctgtc      600

ccagcaaaca cacctgtcta cgctacaggt ctgtaactgg ttcatcaacg cccgccgcag      660

gctcctccct gacatgctga gaaaggatgg caaagatcca aatcagttca caatttcccg      720

ccgtggggcc aagatttctg aaacgagctc tgtggagtcc gtgatgggca tcaaaaactt      780

catgccagct ctagaggaga ccccatttca ttcctgtaca gctgggccaa acccaaccct      840

agggaggcca ctgtctccta agccgtcatc cccgggatca gttttggctc gtccatcagt      900

gatctgccat accactgtga ctgcattgaa agatgtccct ttctctctct gccagtcggt      960

cggtgtggga caaaacacag atatacagca gatagcggcc aaaaacttca cagacacctc     1020

tctcatgtac ccagaggaca cttgtaaatc tggaccaagt acgaatacac agagtggtct     1080

tttcaacact cctcccccta ctccaccgga cctcaaccag gacttcagtg gatttcagct     1140

tctagtggat gttgcactca aacgggctgc agagatggag cttcaggcaa aacttacagc     1200

ttaacccatt ttcaagcaaa acagttctca gaaatgtcat gattgccggg gtgaaggcaa     1260

gagatgaatt gcattatttt atatattttt tattaatatt tgcacatggg attgctaaaa     1320

cagcttcctg ttactgagat gtcttcaatg gaatacagtc attccaagaa ctataaactt     1380

aaagctactg tagaaacaaa gggttttctt ttttaaatgt ttcttggtag attattcata     1440

atgtgagatg gttcccaata tcatgtgatt ttttttttcc tccccttccc tttttttgtt     1500

attttttcag actgtgcaat acttagagaa cctatagcat cttctcattc ccatgtggaa     1560

caggatgccc acatactgtc taattaataa attttccatt ttttttcaaa caagtatgaa     1620

tctagttggt tgatgccttt tttttcatga cataataaag tattttcttt aaaaaaaaaa     1680

aaaaaaa                                                               1687


<210>  1058
<211>  3002
<212>  DNA
<213>  homo sapiens

<400>  1058
ggggaggagg ggagaacggg gagcgcacag cctggacgcg tgcgcaggcg tcaggcgcat       60

agacctgcta gcccctcagc tagcggcccc gcccgcgctt agcatcacta actgggctat      120

ataacctgag cgcccgcgcg gccacgacac gaggaattcg cccacgcagg aggcgcggcg      180

tccggaggcc ccagggttat gagactatca ctgctcagga cctactaaca acaaaggaaa      240

tcgaaacatg accaaatcgt acagcgagag tgggctgatg ggcgagcctc agccccaagg      300

tcctccaagc tggacagacg agtgtctcag ttctcaggac gaggagcacg aggcagacaa      360

gaaggaggac gacctcgaag ccatgaacgc agaggaggac tcactgagga acgggggaga      420

ggaggaggac gaagatgagg acctggaaga ggaggaagaa gaggaagagg aggatgacga      480

tcaaaagccc aagagacgcg gccccaaaaa gaagaagatg actaaggctc gcctggagcg      540

ttttaaattg agacgcatga aggctaacgc ccgggagcgg aaccgcatgc acggactgaa      600

cgcggcgcta gacaacctgc gcaaggtggt gccttgctat tctaagacgc agaagctgtc      660

caaaatcgag actctgcgct tggccaagaa ctacatctgg gctctgtcgg agatcctgcg      720

ctcaggcaaa agcccagacc tggtctcctt cgttcagacg ctttgcaagg gcttatccca      780

acccaccacc aacctggttg cgggctgcct gcaactcaat cctcggactt ttctgcctga      840

gcagaaccag gacatgcccc cccacctgcc gacggccagc gcttccttcc ctgtacaccc      900

ctactcctac cagtcgcctg ggctgcccag tccgccttac ggtaccatgg acagctccca      960

tgtcttccac gttaagcctc cgccgcacgc ctacagcgca gcgctggagc ccttctttga     1020

aagccctctg actgattgca ccagcccttc ctttgatgga cccctcagcc cgccgctcag     1080

catcaatggc aacttctctt tcaaacacga accgtccgcc gagtttgaga aaaattatgc     1140

ctttaccatg cactatcctg cagcgacact ggcaggggcc caaagccacg gatcaatctt     1200

ctcaggcacc gctgcccctc gctgcgagat ccccatagac aatattatgt ccttcgatag     1260

ccattcacat catgagcgag tcatgagtgc ccagctcaat gccatatttc atgattagag     1320

gcacgccagt ttcaccattt ccgggaaacg aacccactgt gcttacagtg actgtcgtgt     1380

ttacaaaagg cagccctttg ggtactactg ctgcaaagtg caaatactcc aagcttcaag     1440

tgatatatgt atttattgtc attactgcct ttggaagaaa caggggatca aagttcctgt     1500

tcaccttatg tattattttc tatagctctt ctatttaaaa aataaaaaaa tacagtaaag     1560

tttaaaaaat acaccacgaa tttggtgtgg ctgtattcag atcgtattaa ttatctgatc     1620

gggataacaa aatcacaagc aataattagg atctatgcaa tttttaaact agtaatgggc     1680

caattaaaat atatataaat atatattttt caaccagcat tttactactt gttacctttc     1740

ccatgctgaa ttattttgtt gtgattttgt acagaatttt taatgacttt ttataatgtg     1800

gatttcctat tttaaaacca tgcagcttca tcaattttta tacatatcag aaaagtagaa     1860

ttatatctaa tttatacaaa ataatttaac taatttaaac cagcagaaaa gtgcttagaa     1920

agttattgtg ttgccttagc acttctttcc tctccaattg taaaaaaaaa aaaaaaaaaa     1980

aaaaaaaaaa aaaaattgca caatttgagc aattcatttc actttaaagt ctttccgtct     2040

ccctaaaata aaaaccagaa tcataatttt caagagaaga aaaaattaag agatacattc     2100

cctatcaaaa catatcaatt caacacatta cttgcacaag cttgtatata catattataa     2160

ataaatgcca acataccctt ctttaaatca aaagctgctt gactatcaca tacaatttgc     2220

actgttactt tttagtcttt tactcctttg cattccatga ttttacagag aatctgaagc     2280

tattgatgtt tccagaaaat ataaatgcat gattttatac atagtcacaa aaatggtggt     2340

ttgtcatata ttcatgtaat aaatctgagc ctaaatctaa tcaggttgtt aatgttggga     2400

tttatatcta tagtagtcaa ttagtacagt agcttaaata aattcaaacc atttaattca     2460

taattagaac aatagctatt gcatgtaaaa tgcagtccag aataagtgct gtttgagatg     2520

tgatgctggt accactggaa tcgatctgta ctgtaatttt gtttgtaatc ctgtatatta     2580

tggtgtaatg cacaatttag aaaacattca tccagttgca ataaaatagt attgaaagtg     2640

agagcaattg ttgcatttct tcttaaaggg attctgtttt tatttttggg gaaagtagtt     2700

gcttttttgc tgagttaaaa aatactaaac actatatgta gaataaaaga aaagaaaaaa     2760

gtttaccttg gcatatgctc ttgtctgttt atcttgcaca gggagtcacc agttctatgt     2820

agataatgaa aagacctaac tgatatttca ttatttggaa tatgggactg gacggcagta     2880

caaacagtgt gtttttttct ttgttttaag tggcttagcc tttaggtttt ttatttccat     2940

ttttaaaaat gattgttaca tgttttcttc tatttctttt tttaaaaggt ggattttaat     3000

aa                                                                    3002


<210>  1059
<211>  9262
<212>  DNA
<213>  homo sapiens

<400>  1059
tagagagatt ggttttcttt ctctcagcat ctccacccaa ccagcagaaa accggtgagt       60

ggggctttta agtgattttc aagaagaatg taacagatgt caaacgggaa aagcacaagg      120

caaagcctgc tctctctgtc tctctgtctc ctcttctcct tttttgcctt attctatccg      180

attttttccc taagcttcta cctgggattt tcctttggaa aagtctctga ggttccacca      240

aaatatggaa cttgattttg gacactttga cgaaagagat aagacatcca ggaacatgcg      300

aggctcccgg atgaatgggt tgcctagccc cactcacagc gcccactgta gcttctaccg      360

aaccagaacc ttgcaggcac tgagtaatga gaagaaagcc aagaaggtac gtttctaccg      420

caatggggac cgctacttca aggggattgt gtacgctgtg tcctctgacc gttttcgcag      480

ctttgacgcc ttgctggctg acctgacgcg atctctgtct gacaacatca acctgcctca      540

gggagtgcgt tacatttaca ccattgatgg atccaggaag atcggaagca tggatgaact      600

ggaggaaggg gaaagctatg tctgttcctc agacaacttc tttaaaaagg tggagtacac      660

caagaatgtc aatcccaact ggtctgtcaa cgtaaaaaca tctgccaata tgaaagcccc      720

ccagtccttg gctagcagca acagtgcaca ggccagggag aacaaggact ttgtgcgccc      780

caagctggtt accatcatcc gcagtggggt gaagcctcgg aaggctgtgc gtgtgcttct      840

gaacaagaag acagcccact cttttgagca agtcctcact gatatcacag aagccatcaa      900

actggagacc ggggttgtca aaaaactcta cactctggat ggaaaacagg taacttgtct      960

ccatgatttc tttggtgatg atgatgtgtt tattgcctgt ggtcctgaaa aatttcgcta     1020

tgctcaggat gatttttctc tggatgaaaa tgaatgccga gtcatgaagg gaaacccatc     1080

agccacagct ggcccaaagg catccccaac acctcagaag acttcagcca agagccctgg     1140

tcctatgcgc cgaagcaagt ctccagctga ctcagcaaac ggaacctcca gcagccagct     1200

ctctaccccc aagtctaagc agtctcccat ctctacgccc accagtcctg gcagcctccg     1260

gaagcacaag gacctgtacc tgcctctgtc cttggatgac tcggactcgc ttggtgattc     1320

catgtaaagg aggggagagt gctcagagtc cagagtacaa atccaagcct atcattgtag     1380

tagggtactt ctgctcaagt gtccaacagg gctattggtg ctttcaagtt tttattttgt     1440

tgttgttgtt attttgaaaa acacattgta atatgttggg tttattttcc tgtgatttct     1500

cctctgggcc actgatccac agttaccaat tatgagagat agattgataa ccatcctttg     1560

gggcagcatt ccagggatgc aaaatgtgct agtccatgac ctttcaatgg aaagcttagg     1620

tgcctgcgtt atatttgccc tgtctaattt tgcccataca gtcttccttc tgtagagggc     1680

tgtttacata tacagcactt aaaatgtttg tgtgggaaaa aaaaaactca ttggcagatc     1740

caagaatgac aaacacaagt gccccttttc tctggatctc aagaatggtg gaggaccctg     1800

gaaggacagc aaggcagctc cccagcctca ctcttcactc ctgattgagg cccgggtttg     1860

ttgtccagca ccaattctgg ctgtcaatgg ggagaaataa accaacaact tataattgtg     1920

acaccagatg cttaggatcc tggtgctggg ttagctaaga gaatagacag aattggaaaa     1980

tactgcagac atttccgaag agtttataaa gcacagtgaa ttcctggtca atctctccac     2040

tgaggcaatt tggaatcaat aagcaattga taatagtttg gagtaaggga cttcatatac     2100

ctgattcctc tagaaggctg tctaacatac cacatgatta catgaactgt atggtatcca     2160

tctatctctg ttctattgaa tgccttgtta acagccaaca ctgaaaacac tgtgagaatt     2220

tgttttcagg tctgacacct ttcagtctct ttttatagca agaaatcaat atccttttta     2280

taaaaattca tgtctgtatt tcaggagcaa actcttcagg ctcctttttt ataaactggt     2340

gatttttctt ttgtctaaaa aacacatgaa gaaaatttac caaaaaaaaa aaaaaaagca     2400

gaagaataat gtagtttaga aattatgctg tcactgccaa acagtaacct ccaggagaaa     2460

acaagatgaa tagcagaggc caattcaata gaatcagttt tttgatagct ttttaacagt     2520

tatgcttgca ttaataattt caatgtggac cagacattct aattatattt taaatgaaat     2580

gttacagcat attttaagca actcttttta tctataatcc taatatttca tactgaagac     2640

acagaaatct ttcacttgtc tttaacatta gaaaggattt ctctttacta aggactgatc     2700

atttgaaata gttttcagtc ttttgagata caggtttata acactgcttt tttttttctg     2760

taatcatagc ccataatggc aaagacaact aaatttaagt gaaggtcatg catgccaatt     2820

ctgtgtttgc ttttagcaga tatgaagatt tccttatttc tttgtaattg tgcagatatt     2880

ttgaaaggca cagcattcga agccaagctg ctgtttggct actgaatggc ttgcagttgt     2940

tcctccactc taaatggaat gagcttgctg tgtgtgtgtg tggtggtggt gggagggggt     3000

ggtgcatgtg tgtgtgtgtg tgtgcatctg cagctgcttc aaaattagga aatactacag     3060

gacacccctg taatggattg gtggcaactg ggtggcactg ctgatgtgca ctgtgtaggg     3120

gggaacccag tggtggtggg gtagctcaga tgcccctaga caagcttcag atgtctgtag     3180

ctaccagaaa cattttcggt tcaggaaaag tgagatgatg gtagtactgg tttctggtga     3240

aattgaagaa ccccaaatga tgaggatctc tttttgcccc ctctcctttt tttgtagacc     3300

cattcaaaac cattaataag cccattttac taagccccta tttctttcta gaagctcagg     3360

gttttcttag tgcctcccag aacattttgt agttaattgg gaaaaagtga tacttggatt     3420

agggggtgtg ggcataaaga atggtgggag gcctgatttt aaacttcagg ccagaacccc     3480

caatgactcc acccatagtc tcactttagg tctcatttag tccatcacct ttattttaag     3540

ttgaggaagt ggaggctggt aaagagcagg accagaggaa gaatccagat ttccttatgc     3600

ttgggcctca cactagctct ctgagtattt ccttgattgc ggtatatgta ctactagaaa     3660

ataccaaatg gatatatttt ctttaggata acctttgaac caacaatctt caataacaat     3720

agtacatctt ccatcttact tttaatcgag tataaggaaa tgtttcttta tggccatttt     3780

ggagggagca ggggatgagg cttggcatag tccaaaattt aagtctccaa taattaattg     3840

cattttaaat tggcccactt tcaaggcaat tttttttgtg tgtctgtaac tgagctcctc     3900

cacccctgtc attcacttcc aattttaccc aatccaattt tagcactcaa gttccattgt     3960

gttaatttct gcacggtcaa caaacatcaa gtcagcaagc atttgccacc actccctata     4020

cttctccctc cttcttacac acacacacac acacacacac acaatccatc tcttgcttgt     4080

tcctacctcc tgatttttct tccctacaga aatagaaata gggacaaaga aggggaaaat     4140

gtatatattg gggctgggct gaacaactaa cttcataagt agtattaact aggggtaaat     4200

tgagagaaaa gctccttttc tcttcactgt tttggaaagg atagccatta gcatgactgc     4260

tttgtgtcct tatggacttt agtattagcc tagattgaat tatagcgttt tctagctgga     4320

aggaacctta agatcacatc atctactcct ctactccaaa tttctcattc ttcaggccag     4380

gaaaccgaga cacagaggta aagtaatttc cccaaggtca cacagctggc tggggcagga     4440

ttgggtttac aacccacatc tcctggctct tattccaggg ccttttccca ctaagtagta     4500

ttgccttcca ttaggctcct gagagttatt tctcagggtc atgttgcatc ttggagccac     4560

atgctgctgc cctgatctca gtgggaaatc cacccagcaa cctaatacag ccccttttcc     4620

ctgcattcac ctggttccca tccacatggg ttgcagatgt ccttgaagag agtgaggcat     4680

tgagggccaa taggagcaat ggggtccctg gccttgtcca tctgattcag gagatcactg     4740

ctccatcgtg aggagccctc tgaatagccc cccactgaat gcttgccttg cccaaatgga     4800

atggaggaag attgattttc tccatcagtt caccttgtgt catctcataa tggttggtct     4860

ttccaggctg agggaaatgt ttcttgtttc cagagtagaa aaagaaagag tggaacaata     4920

gctttgttca tcctaacttt ctgagatggc ttttcaacat tttaaaaaaa ctagtgtggc     4980

taccattcac tggcaatgat ttcttttaga atatgggagt aagatgagct agagaaaata     5040

acctggtctc actgtggttg ccctcatcca caatgtcccc aaagccatcc tgctctgatg     5100

aggacaattt ccaggtataa gcaaggggct ttgtgacaaa aatgtaccct ggctgatgtt     5160

aaacattggc tcctgtgttt gcaccaaaat agcaagctgt gtgctctata cactcttccc     5220

atcgtcttgt gtacactgct cctgtggcct tccacagcag aaaccagggc aaaagggtcc     5280

aaacacatgg ttttccttgc tgcaaggctc ttcctgggaa ctaagggggt atttattagt     5340

tcagttctaa gagacctcct tctgggctta ccccactcct caggtacttc tctctccttc     5400

ctccttctcc tccacagtca caagtaacca aggaacctga aagtggatgt gtagctattt     5460

gaagaaggca aggaaccctg agattcttct ttgaatcctc tagtccaagt cttagaccag     5520

tgattggtgc ttaccttgaa caaaattttg tctgtgttcc taatcccttc aatactctgg     5580

gtacaatgct cccaatcacc ctgcacattt gattctaaat ggcttttatt ttttaaaaat     5640

ccatatccct aggacaagag aacaggatgc ctatatcccc aaaatgagct ccaggacact     5700

gatgggaatg atcccaaaga tcaccccacc tcagaaacgt ctgtgccaag agacttcccc     5760

agatagaaac actgggacag tggtttgaac gacttctttt atggttgtcc agtttgctat     5820

ggaaataaaa ggcattgatt ttttaaaaag atgattggaa cctgtctttg gccacatagg     5880

gccacttgga tccatttcca ggccttactc atatattgcc ttcactgaag ggctttggct     5940

ttaagtccca gactggtctc ccaagtgaac cataagtgtt ttggagctca tctggggtga     6000

ggcatgagaa tgttgcccca tctatccctt caggaaaagg tgccttccct ccctttctcc     6060

taaagcctgg tccccagaaa ttgtttttgt ctccaaaagt ctagtatggt ctttatacac     6120

ccagactctt agtgttgcgt cctgccttgt ttccttgtta aggatctatg cagacctccc     6180

gctttggctt agctagcgtg acattggcta tcatttgaca agactaactt tttttttttt     6240

ttttttttga ctgagtctcc ctctgtcacc taggctggag tgcagtggca caatcttggc     6300

tcgctgcaac cttcaccctt cacctcccag gtcgaagcga ttctcctgcc tcagtctccc     6360

gagtagctgg gattacaggc gtgcgccacc aaatctggct atttttttat tattattatt     6420

tttagtagag atggggtttc accatgttgg ccagactggt cttgaactct tggcctcaaa     6480

ttatctgccc acctcggcct cccaaagtgc tgggattaca ggcatgagcc accatgccca     6540

gctgacaaga ctaatttttt atcccttggt ttattggctt caacatcttc tggaatcaga     6600

ggtgattttt tcttaccttg gatgcctgag actaggggag tatagaattc caattggtaa     6660

ttaaggcatc tttctgctcc tgatcagaag ggcaggttag ttgggagagg tcagatggca     6720

caacagaagt caccttgtaa gtaaggcaaa gacttgaagg cattagcgtt tctcattact     6780

aggtcaataa cctgagggaa tcaatggctt tttgccgctc tacctcttgt gtatctcttt     6840

gacttttctt tctctgtcta gtttcctctg ttctcagttt atattctatg ttatcagtct     6900

ctctttccac agtacaaaca tccatccttt ctcctgtgca attctgtctc tccctcttat     6960

tatctttatt tgtacttttt ccttcctccc tgtctaggca ttgggcatgt gcctcttctt     7020

agcctgtgat tttgccttgg gactgatgat aaattatttc cagattcaat cagccctggt     7080

cctaccccag tccaatcaga agtatgttgg tgggaatcaa cctgatcctg gccctttctt     7140

cttctccatt ttcattcgta atccccctca gcagatcttt acaagcagtt tccttatagc     7200

tcatgtatct ttaggtcttt gccttccaag cactgtacag aatactttgt ggttcctttt     7260

tagtctgaca ttttgtggag cagtgaagcg tgctcagaga cataatcagc tgaagagaaa     7320

aaatccaccc atggatttat atcagctaaa tactaataat tgattttgtt tgatgtgccc     7380

ataattttta aagctgcaat ataatataat gagggaccac aggtaatttc tcctgtcatt     7440

tgttttggct ggatgggggt gggggagtaa ttgcttaaag ttttaccatt acacattaaa     7500

ctctctataa taatcttgtt tggggcttgc taactgttga gctgttttaa ctaaactggt     7560

aggcaatcgg agttgattta aatgaaaaga taatttaaca aatctatact ataaaaagag     7620

acatttgctt aattgacatg tattttttcc ttctgagtca cctaaacatt tactcttgac     7680

accaactgtt catgatactg aatagacagt ccatataaga gaaattagtg gacctaaaga     7740

agccagattg taggtgttaa tttattaaac agagtgcaaa gcccttggaa atgtcactgc     7800

ttggcaatac catatggaat gccaaaattt acaatgactt ttctttataa gttatccaaa     7860

agggatttga acaagtaaga ggttatgcca aaatgtctcc aatgtatggt cctgtaatat     7920

attgcagctt gaagccaatg atcccttatg acttgtatac aactaatgca tgttttattg     7980

aattttgcat ttcccacgtg tggtaagttc tttaaaatgt ttttgatcac ctttttgtgc     8040

cattaaactt gtacagaaaa tgtttttatg gccattttca aagggagaaa gtttaaaatg     8100

gaaacagccc accctttctg ccctatagct gtagttagaa ttgagtacct gtagcaaaac     8160

agctgtaatt ggtggttgta gtgttagagg tgttagcttg ctagtgacta gctttggaga     8220

gtaaatgcat ggtattgtac atcacatttc ttaactcgtt ttaacctctg aaaagaatat     8280

attcttcttt gtagtccttc ttcccacccc cttgccctct ccctctccct gctcccagtt     8340

gtcttacagt tgtaaatatc tgatttgagg cccaataact cttgccaagt aaagtcagca     8400

aacaacaaac aaaccaaaat gtggggaaaa ggcatttctc aaccatctct cagcagttat     8460

tgatcatttc ttaaggaaca gcattgtgat caaagactca actttacgta aaaatcagtg     8520

gtaaattggg gttgtatttg gccatttgat tacatttcag gattgaatag ttttcagaat     8580

cacatgtaat ccaaagacag taggtagtga tgtcccttat ccctgcagct gttttaagat     8640

agagacctca gaagactctg cttgaccgat gaccaataat tatttgaaaa aaaaagaaaa     8700

aatgagagaa ataaaacaga tatttaagaa ctttagccac ctatttagaa tagttatagc     8760

cagaaaaaaa aacaagggca tgagttcaaa tgcattacta tcagtgtcct aggcaatacc     8820

taacctactc tgaaattgtg attcaaaagc agtatttcaa gaggcattct ccttttttgg     8880

tttgctgacc ccacttggac tggtaggttt ggtgaggccc ccataaacca gctggagcag     8940

acccttttca tctcctgtgc ctgtaacacc cctcttcccc caccccctcc gcaattcaat     9000

gagggctttc ttgggtcaga ggacttcaag gttgtctaga gaagtttgcc atgtgtgtaa     9060

ggtgctgtga actgtgagtg ctgaagattc gcagcattca ataccaggca gccaaagagc     9120

tgctcttgca attattttgg ctctcaagct ctgttcttca tcgcattctc atttctgtgt     9180

acatttgcaa gatgtgtgta atgtcatttt ccaaaaataa aatttgattt caataaaaaa     9240

aaaaaaaaaa aaaaaaaaaa aa                                              9262


<210>  1060
<211>  9141
<212>  DNA
<213>  homo sapiens

<400>  1060
accatagagt gaatctcaga acaggaagcg gaggcataag cagagaggat tctggaaagg       60

tctctttgtt ttcttatcca cagagaaaga aagaaaaaaa attgtaacta atttgtaaac      120

ctctgtggtc aaaaaaaaaa aaaaaaaaaa aagctgaaca gctgcagagg aagacacgtt      180

ataccctaac catcttggat gctgggcttt gttatgctgt aattcataag gctctgtttt      240

atcagagatt atggagcaag aaaactgaag ccaagccaca tcaaggtttg acagggatga      300

gatacctgtc aaggattcat agtagagtgg cttactggga aaggagcaaa gaatctcttc      360

tagggatatt gtaagaataa atgagataat tcacagaagg gacctggagc ttttccggaa      420

aaaggtgctg tgactatcta aggtaattcg tatgcaagaa gctacacgta attaaatgtg      480

caggatgaaa agatggcaca ggcactgttg gtacccccag gacctgaaag cttccgcctt      540

tttactagag aatctcttgc tgctatcgaa aaacgtgctg cagaagagaa agccaagaag      600

cccaaaaagg aacaagataa tgatgatgag aacaaaccaa agccaaatag tgacttggaa      660

gctggaaaga accttccatt tatttatgga gacattcctc cagagatggt gtcagagccc      720

ctggaggacc tggatcccta ctatatcaat aagaaaactt ttatagtaat gaataaagga      780

aaggcaattt tccgattcag tgccacctct gccttgtata ttttaactcc actaaaccct      840

gttaggaaaa ttgctatcaa gattttggta cattctttat tcagcatgct tatcatgtgc      900

actattttga ccaactgtgt atttatgacc ttgagcaacc ctcctgactg gacaaagaat      960

gtagagtaca cattcactgg aatctatacc tttgagtcac ttataaaaat cttggcaaga     1020

gggttttgct tagaagattt tacgtttctt cgtgatccat ggaactggct ggatttcagt     1080

gtcattgtga tggcatatgt gacagagttt gtggacctgg gcaatgtctc agcgttgaga     1140

acattcagag ttctccgagc actgaaaaca atttcagtca ttccaggttt aaagaccatt     1200

gtgggggccc tgatccagtc ggtaaagaag ctttctgatg tgatgatcct gactgtgttc     1260

tgtctgagcg tgtttgctct cattgggctg cagctgttca tgggcaatct gaggaataaa     1320

tgtttgcagt ggcccccaag cgattctgct tttgaaacca acaccacttc ctactttaat     1380

ggcacaatgg attcaaatgg gacatttgtt aatgtaacaa tgagcacatt taactggaag     1440

gattacattg gagatgacag tcacttttat gttttggatg ggcaaaaaga ccctttactc     1500

tgtggaaatg gctcagatgc aggccagtgt ccagaaggat acatctgtgt gaaggctggt     1560

cgaaacccca actatggcta cacaagcttt gacaccttta gctgggcttt cctgtctcta     1620

tttcgactca tgactcaaga ctactgggaa aatctttacc agttgacatt acgtgctgct     1680

gggaaaacat acatgatatt ttttgtcctg gtcattttct tgggctcatt ttatttggtg     1740

aatttgatcc tggctgtggt ggccatggcc tatgaggagc agaatcaggc caccttggaa     1800

gaagcagaac aaaaagaggc cgaatttcag cagatgctcg aacagcttaa aaagcaacag     1860

gaagaagctc aggcagttgc ggcagcatca gctgcttcaa gagatttcag tggaataggt     1920

gggttaggag agctgttgga aagttcttca gaagcatcaa agttgagttc caaaagtgct     1980

aaagaatgga ggaaccgaag gaagaaaaga agacagagag agcaccttga aggaaacaac     2040

aaaggagaga gagacagctt tcccaaatcc gaatctgaag acagcgtcaa aagaagcagc     2100

ttccttttct ccatggatgg aaacagactg accagtgaca aaaaattctg ctcccctcat     2160

cagtctctct tgagtatccg tggctccctg ttttccccaa gacgcaatag caaaacaagc     2220

attttcagtt tcagaggtcg ggcaaaggat gttggatctg aaaatgactt tgctgatgat     2280

gaacacagca catttgaaga cagcgaaagc aggagagact cactgtttgt gccgcacaga     2340

catggagagc gacgcaacag taacgttagt caggccagta tgtcatccag gatggtgcca     2400

gggcttccag caaatgggaa gatgcacagc actgtggatt gcaatggtgt ggtttccttg     2460

gtgggtggac cttcagctct aacgtcacct actggacaac ttcccccaga gggcaccacc     2520

acagaaacgg aagtcagaaa gagaaggtta agctcttacc agatttcaat ggagatgctg     2580

gaggattcct ctggaaggca aagagccgtg agcatagcca gcattctgac caacacaatg     2640

gaagaacttg aagaatctag acagaaatgt ccgccatgct ggtatagatt tgccaatgtg     2700

ttcttgatct gggactgctg tgatgcatgg ttaaaagtaa aacatcttgt gaatttaatt     2760

gttatggatc catttgttga tcttgccatc actatttgca ttgtcttaaa taccctcttt     2820

atggccatgg agcactaccc catgactgag caattcagta gtgtgttgac tgtaggaaac     2880

ctggtcttta ctgggatttt cacagcagaa atggttctca agatcattgc catggatcct     2940

tattactatt tccaagaagg ctggaatatc tttgatggaa ttattgtcag cctcagttta     3000

atggagcttg gtctgtcaaa tgtggaggga ttgtctgtac tgcgatcatt cagactgctt     3060

agagttttca agttggcaaa atcctggccc acactaaata tgctaattaa gatcattggc     3120

aattctgtgg gggctctagg aaacctcacc ttggtgttgg ccatcatcgt cttcattttt     3180

gctgtggtcg gcatgcagct ctttggtaag agctacaaag aatgtgtctg caagatcaat     3240

gatgactgta cgctcccacg gtggcacatg aacgacttct tccactcctt cctgattgtg     3300

ttccgcgtgc tgtgtggaga gtggatagag accatgtggg actgtatgga ggtcgctggc     3360

caaaccatgt gccttattgt tttcatgttg gtcatggtca ttggaaacct tgtggttctg     3420

aacctctttc tggccttatt gttgagttca tttagctcag acaaccttgc tgctactgat     3480

gatgacaatg aaatgaataa tctgcagatt gcagtaggaa gaatgcaaaa gggaattgat     3540

tatgtgaaaa ataagatgcg ggagtgtttc caaaaagcct tttttagaaa gccaaaagtt     3600

atagaaatcc atgaaggcaa taagatagac agctgcatgt ccaataatac tggaattgaa     3660

ataagcaaag agcttaatta tcttagagat gggaatggaa ccaccagtgg tgtaggtact     3720

ggaagcagtg ttgaaaaata cgtaatcgat gaaaatgatt atatgtcatt cataaacaac     3780

cccagcctca ccgtcacagt gccaattgct gttggagagt ctgactttga aaacttaaat     3840

actgaagagt tcagcagtga gtcagaacta gaagaaagca aagagaaatt aaatgcaacc     3900

agctcatctg aaggaagcac agttgatgtt gttctacccc gagaaggtga acaagctgaa     3960

actgaacccg aagaagacct taaaccggaa gcttgtttta ctgaaggatg tattaaaaag     4020

tttccattct gtcaagtaag tacagaagaa ggcaaaggga agatctggtg gaatcttcga     4080

aaaacctgct acagtattgt tgagcacaac tggtttgaga ctttcattgt gttcatgatc     4140

cttctcagta gtggtgcatt ggcctttgaa gatatataca ttgaacagcg aaagactatc     4200

aaaaccatgc tagaatatgc tgacaaagtc tttacctata tattcattct ggaaatgctt     4260

ctcaaatggg ttgcttatgg atttcaaaca tatttcacta atgcctggtg ctggctagat     4320

ttcttgatcg ttgatgtttc tttggttagc ctggtagcca atgctcttgg ctactcagaa     4380

ctcggtgcca tcaaatcatt acggacatta agagctttaa gacctctaag agccttatcc     4440

cggtttgaag gcatgagggt ggttgtgaat gctcttgttg gagcaattcc ctctatcatg     4500

aatgtgctgt tggtctgtct catcttctgg ttgatcttta gcatcatggg tgtgaatttg     4560

tttgctggca agttctacca ctgtgttaac atgacaacgg gtaacatgtt tgacattagt     4620

gatgttaaca atttgagtga ctgtcaggct cttggcaagc aagctcggtg gaaaaacgtg     4680

aaagtaaact ttgataatgt tggcgctggc tatcttgcac tgcttcaagt ggccacattt     4740

aaaggctgga tggatattat gtatgcagct gttgattcac gagatgttaa acttcagcct     4800

gtatatgaag aaaatctgta catgtattta tactttgtca tctttatcat ctttgggtca     4860

ttcttcactc tgaatctatt cattggtgtc atcatagata acttcaacca gcagaaaaag     4920

aagtttggag gtcaagacat ctttatgaca gaggaacaga aaaaatatta caatgcaatg     4980

aagaaacttg gatccaagaa acctcagaaa cccatacctc gcccagcaaa caaattccaa     5040

ggaatggtct ttgattttgt aaccagacaa gtctttgata tcagcatcat gatcctcatc     5100

tgcctcaaca tggtcaccat gatggtggaa acggatgacc agggcaaata catgacccta     5160

gttttgtccc ggatcaacct agtgttcatt gttctgttca ctggagaatt tgtgctgaag     5220

ctcgtctccc tcagacacta ctacttcact ataggctgga acatctttga ctttgtggtg     5280

gtgattctct ccattgtagg tatgtttctg gctgagatga tagaaaagta ttttgtgtcc     5340

cctaccttgt tccgagtgat ccgtcttgcc aggattggcc gaatcctacg tctgatcaaa     5400

ggagcaaagg ggatccgcac gctgctcttt gctttgatga tgtcccttcc tgcgttgttt     5460

aacatcggcc tcctgctctt cctggtcatg tttatctatg ccatctttgg gatgtccaac     5520

tttgcctatg ttaaaaagga agctggaatt gatgacatgt tcaactttga gacctttggc     5580

aacagcatga tctgcttgtt ccaaattaca acctctgctg gctgggatgg attgctagca     5640

cctattctta atagtgcacc acccgactgt gaccctgaca caattcaccc tggcagctca     5700

gttaagggag actgtgggaa cccatctgtt gggattttct tttttgtcag ttacatcatc     5760

atatccttcc tggttgtggt gaacatgtac atcgcggtca tcctggagaa cttcagtgtt     5820

gctactgaag aaagtgcaga gcccctgagt gaggatgact ttgagatgtt ctatgaggtt     5880

tgggaaaagt ttgatcccga tgcgacccag tttatagagt tctctaaact ctctgatttt     5940

gcagctgccc tggatcctcc tcttctcata gcaaaaccca acaaagtcca gcttattgcc     6000

atggatctgc ccatggtcag tggtgaccgg atccactgtc ttgatatttt atttgccttt     6060

acaaagcgtg ttttgggtga gagtggagag atggatgccc ttcgaataca gatggaagac     6120

aggtttatgg catcaaaccc ctccaaagtc tcttatgagc ctattacaac cactttgaaa     6180

cgtaaacaag aggaggtgtc tgccgctatc attcagcgta atttcagatg ttatctttta     6240

aagcaaaggt taaaaaatat atcaagtaac tataacaaag aggcaattaa agggaggatt     6300

gacttaccta taaaacaaga catgattatt gacaaactaa atgggaactc cactccagaa     6360

aaaacagatg ggagttcctc taccacctct cctccttcct atgatagtgt aacaaaacca     6420

gacaaggaaa agtttgagaa agacaaacca gaaaaagaaa gcaaaggaaa agaggtcaga     6480

gaaaatcaaa agtaaaaaga aacaaagaat tatctttgtg atcaattgtt tacagcctat     6540

gaaggtaaag tatatgtgtc aactggactt caagaggagg tccatgccaa actgactgtt     6600

ttaacaaata ctcatagtca gtgcctatac aagacagtga agtgacctct ctgtcactgc     6660

aactctgtga agcagggtat caacattgac aagaggttgc tgtttttatt accagctgac     6720

actgctgagg agaaacccaa tggctaccta gactataggg atagttgtgc aaagtgaaca     6780

ttgtaactac accaaacacc tttagtacag tccttgcatc cattctattt ttaacttcca     6840

tatctgccat atttttacaa aatttgttct agtgcatttc catggtcccc aattcatagt     6900

ttattcataa tgctatgtca ctatttttgt aaatgaggtt tacgttgaag aaacagtata     6960

caagaaccct gtctctcaaa tgatcagaca aaggtgtttt gccagagaga taaaattttt     7020

gctcaaaacc agaaaaagaa ttgtaatggc tacagtttca gttacttcca ttttctagat     7080

ggctttaatt ttgaaagtat tttagtctgt tatgtttgtt tctatctgaa cagttatgtg     7140

cctgtaaagt ctcctctaat atttaaagga ttatttttat gcaaagtatt ctgtttcagc     7200

aagtgcaaat tttattctaa gtttcagagc tctatattta atttaggtca aatgctttcc     7260

aaaaagtaat ctaataaatc cattctagaa aaatatatct aaagtattgc tttagaatag     7320

ttgttccact ttctgctgca gtattgcttt gccatcttct gctctcagca aagctgatag     7380

tctatgtcaa ttaaataccc tatgttatgt aaatagttat tttatcctgt ggtgcatgtt     7440

tgggcaaata tatatatagc ctgataaaca acttctatta aatcaaatat gtaccacagt     7500

gtatgtgtct tttgcaagct tccaacaggg atgtatcctg tatcattcat taaacatagt     7560

ttaaaggcta tcactaatgc atgttaatat tgcctatgct gctctatttt actcaatcca     7620

ttcttcacaa gtcttggtta aagaatgtca catattggtg atagaatgaa ttcaacctgc     7680

tctgtccatt atgtcaagca gaataatttg aagctattta caaacacctt tacttttgca     7740

cttttaattc aacatgagta tcatatggta tctctctaga tttcaaggaa acacactgga     7800

tactgcctac tgacaaaacc tattcttcat attttgctaa aaatatgtct aaaacttgtt     7860

taaatataaa taatgtaaaa atataatcaa ctttatttgt cagcattttg tacataagaa     7920

aattattttc aggttgatga catcacaatt tattttactt tatgcttttg cttttgattt     7980

ttaatcacaa ttccaaactt ttgaatccat aagatttttc aatggataat ttcctaaaat     8040

aaaagttaga taatgggttt tatggatttc tttgttataa tatattttct accattccaa     8100

taggagatac attggtcaaa cactcaaacc tagatcattt tctaccaact atggttgcct     8160

caatataacc ttttattcat agatgttttt ttttattcaa cttttgtagt atttacgtat     8220

gcagactagt cttatttttt taattcctgc tgcactaaag ctattacaaa tataacatgg     8280

actttgttct ttttagccat gaacaaagtg gcaaagttgt gcaattacct aacatgatat     8340

aaatttttgt tttttgcaca aaccaaaagt ttaatgttaa ttctttttac aaaactattt     8400

actgtagtgt attgaagaac tgcatgcagg gaattgctat tgctaaaaag aatggtgagc     8460

tacgtcatta ttgagccaaa agaataaatt tcatttttta ttgcatttca cttattggcc     8520

tctggggttt tttgtttttg ttttttgctg ttggcagttt aaaatatata taattaataa     8580

aacctgtgct tgatctgaca tttgtataca taaaagttta catgaatttt acaacaaact     8640

agtgcatgat tcaccaagca gtactacaga acaaaggcaa attaaaagca gctttgtgaa     8700

cttttatgtg tgcaaaggat caagttcaca tgttccaact ttcaggtttg ataataatag     8760

tagtaaccac ctacaatagc tttcaatttc aattaactcc cttggctata agcatctaaa     8820

ctcatcttct ttcaatataa ttgatgctat ctcctaatta cttggtggct aataaatgtt     8880

acattctttg ttacttaaat gcattatata aactcctatg tatacataag gtattaatga     8940

tatagttatt gagaatttat attaactttt ttttcaagaa cccttggatt tatgtgaggt     9000

caaaaccaaa ctcttattct cagtggaaaa ctccagttgt aatgcatatt tttaaagaca     9060

atttggatct aaatatgtat ttcataattc tcccataata aattatataa ggtggctaat     9120

tggaaaaaaa aaaaaaaaaa a                                               9141


<210>  1061
<211>  2676
<212>  DNA
<213>  homo sapiens

<400>  1061
ttggagctgt ctcagcctgc agttgcttta tataaaccat cccttttatg ggagttgaag       60

cactgtatga aaagggtttt tgtctcatgt tgaccttgtt tagtcacatt aacgcacaca      120

tcagttccag gccccattcc attctctgaa catcttctga cacactgaca gtgctgagca      180

gagcaaggtt gggttcgctc ctctggcaga acctcggctc tcaggaggtc cttgttccag      240

ggaacagctg cttctctggg gctgggctct actccctgca gcccctcgca ctacccagct      300

ggaaccaggg acaacgcctg agtccaaccc tcgtgtctat tttccagaaa acgggcaatg      360

ctgtgagagc cattggaaga ctgtcctcta tggcaatgat ctcagggctc agtggcagga      420

aatcctcaac agggtcacca accagcccgc tcaatgcaga aaaactagaa tctgaagatg      480

tgtcccaagc tttccttgag gctgttgctg aggaaaagcc tcatgtaaaa ccctatttct      540

ctaagaccat tcgcgattta gaagttgtgg agggaagtgc tgctagattt gactgcaaga      600

ttgaaggata cccagacccc gaggttgtct ggttcaaaga tgaccagtca atcagggagt      660

cccgccactt ccagatagac tacgatgagg acgggaactg ctctttaatt attagtgatg      720

tttgcgggga tgacgatgcc aagtacacct gcaaggctgt caacagtctt ggagaagcca      780

cctgcacagc agagctcatt gtggaaacga tggaggaagg tgaaggggaa ggggaagagg      840

aagaagagtg aaacaaagcc agagaaaagc agtttctaag tcatattaaa aggactattt      900

ctctaaaact caaaaaaaaa aaaaaaactc aagatagtaa aagcacctag tgtgatagat      960

tatcggttag gtcatttgtg ggttgattct tcagaaacag cagttgatac ctagcagcgt     1020

tattgatggg cattaatcta tgttagttgg caccttaaga tactagtgca gctagatttc     1080

atttagggaa atcaccagta acttgactga ccaattgatt ttagagagaa agtaaccaaa     1140

ccaaatattt atctgggcaa agtcataaat tctccacttg aatgcgctca tgaaaaataa     1200

ggccaaaaca agagttctgg gccacagctc agcccagagg gttcctgggg atgggaggcc     1260

tctctctccc caccccctga ctctagagaa ctgggttttc tcccagtact ccagcaattc     1320

atttctgaaa gcagttgagc cactttattc caaagtacac tgcagatgtt caaactctcc     1380

atttctcttt ccccttccac ctgccagttt tgctgactct caacttgtca tgagtgtaag     1440

cattaaggac attatgcttc ttcgattctg aagacaggtc cctgctcatg gatgactctg     1500

gcttccttag gaaaatattt ttcttccaaa atcagtagga aatctaaact tatcccctct     1560

ttgcagatgt ctagcagctt cagacatttg gttaagaacc catgggaaaa aaaaaatcct     1620

tgctaatgtg gtttcctttg taaaccagga ttcttatttg tgctgttata gaatatcagc     1680

tctgaacgtg tggtaaagat ttttgtgttt gaatatagga gaaatcagtt tgctgaaaag     1740

ttagtcttaa ttatctattg gccacgatga aacagatttc aactgataaa gagctggaga     1800

actccatgta ctttggaatc tcctccaaga tagccagagt ttaatacatc ttcattctca     1860

acactctcca aagaacttga cctaccttat gggttccata tttttcttct taaatgtgca     1920

tcaatcatgc cttgccccca acctttaaat atattcttag acctggtaaa tgcactcaga     1980

cttgcgtctt taggaatttt taactttctt tcactacatt ggcacttaaa ttttttcttt     2040

ataaagcttt ttgaaggtca taaacaaaga ccataattga tgatagacct aatacatttc     2100

ctctgtgtgt gtgtgtaaca ttccaaatac tttttttttc ttttccactg tttgtaaggt     2160

gcaacaattt aatattttta agggactttt taagagttcc ttaagaacca atttaaaatt     2220

acttcagtgc aatcctacac agtatcaaca ttagaatttt gatattagtc ttatgttatc     2280

ttccattcta tttttatctg ctttttgctg ctagtttcaa actgccagta tttttccttt     2340

tgcttttaaa atagttacaa tatttttcat gatagccaca gtattgccac agtttattat     2400

aataaagggt ttttatttga tttagcgcat tcaaagcttt tttctatcac ttttgtgttc     2460

agaatataac ctttgtgtgc gtgtatgttg tgtgtgtgca tgtgtggcgt atatgtgtgt     2520

tacaggttaa tgccttcttg gaattgtgtt aatgttctct tggtttatta tgccatcaga     2580

atggtaaatg agaacactac aactgtagtc agctcacaat ttttaaataa aggataccac     2640

agtgcatgct gtttgttcaa aaaaaaaaaa aaaaaa                               2676


<210>  1062
<211>  2679
<212>  DNA
<213>  homo sapiens

<400>  1062
ttggagctgt ctcagcctgc agttgcttta tataaaccat cccttttatg ggagttgaag       60

cactgtatga aaagggtttt tgtctcatgt tgaccttgtt tagtcacatt aacgcacaca      120

tcagttccag gccccattcc attctctgaa catcttctga cacactgaca gtgctgagca      180

gagcaaggtt gggttcgctc ctctggcaga acctcggctc tcaggaggtc cttgttccag      240

ggaacagctg cttctctggg gctgggctct actccctgca gcccctcgca ctacccagct      300

ggaaccaggg acaacgcctg agtccaaccc tcgtgtctat tttccagaaa acgggcaatg      360

ctgtgagagc cattggaaga ctgtcctcta tggcaatgat ctcagggctc agtggcagga      420

aatcctcaac agggtcacca accagcccgc tcaatgcaga aaaactagaa tctgaagaag      480

atgtgtccca agctttcctt gaggctgttg ctgaggaaaa gcctcatgta aaaccctatt      540

tctctaagac cattcgcgat ttagaagttg tggagggaag tgctgctaga tttgactgca      600

agattgaagg atacccagac cccgaggttg tctggttcaa agatgaccag tcaatcaggg      660

agtcccgcca cttccagata gactacgatg aggacgggaa ctgctcttta attattagtg      720

atgtttgcgg ggatgacgat gccaagtaca cctgcaaggc tgtcaacagt cttggagaag      780

ccacctgcac agcagagctc attgtggaaa cgatggagga aggtgaaggg gaaggggaag      840

aggaagaaga gtgaaacaaa gccagagaaa agcagtttct aagtcatatt aaaaggacta      900

tttctctaaa actcaaaaaa aaaaaaaaaa ctcaagatag taaaagcacc tagtgtgata      960

gattatcggt taggtcattt gtgggttgat tcttcagaaa cagcagttga tacctagcag     1020

cgttattgat gggcattaat ctatgttagt tggcacctta agatactagt gcagctagat     1080

ttcatttagg gaaatcacca gtaacttgac tgaccaattg attttagaga gaaagtaacc     1140

aaaccaaata tttatctggg caaagtcata aattctccac ttgaatgcgc tcatgaaaaa     1200

taaggccaaa acaagagttc tgggccacag ctcagcccag agggttcctg gggatgggag     1260

gcctctctct ccccaccccc tgactctaga gaactgggtt ttctcccagt actccagcaa     1320

ttcatttctg aaagcagttg agccacttta ttccaaagta cactgcagat gttcaaactc     1380

tccatttctc tttccccttc cacctgccag ttttgctgac tctcaacttg tcatgagtgt     1440

aagcattaag gacattatgc ttcttcgatt ctgaagacag gtccctgctc atggatgact     1500

ctggcttcct taggaaaata tttttcttcc aaaatcagta ggaaatctaa acttatcccc     1560

tctttgcaga tgtctagcag cttcagacat ttggttaaga acccatggga aaaaaaaaat     1620

ccttgctaat gtggtttcct ttgtaaacca ggattcttat ttgtgctgtt atagaatatc     1680

agctctgaac gtgtggtaaa gatttttgtg tttgaatata ggagaaatca gtttgctgaa     1740

aagttagtct taattatcta ttggccacga tgaaacagat ttcaactgat aaagagctgg     1800

agaactccat gtactttgga atctcctcca agatagccag agtttaatac atcttcattc     1860

tcaacactct ccaaagaact tgacctacct tatgggttcc atatttttct tcttaaatgt     1920

gcatcaatca tgccttgccc ccaaccttta aatatattct tagacctggt aaatgcactc     1980

agacttgcgt ctttaggaat ttttaacttt ctttcactac attggcactt aaattttttc     2040

tttataaagc tttttgaagg tcataaacaa agaccataat tgatgataga cctaatacat     2100

ttcctctgtg tgtgtgtgta acattccaaa tacttttttt ttcttttcca ctgtttgtaa     2160

ggtgcaacaa tttaatattt ttaagggact ttttaagagt tccttaagaa ccaatttaaa     2220

attacttcag tgcaatccta cacagtatca acattagaat tttgatatta gtcttatgtt     2280

atcttccatt ctatttttat ctgctttttg ctgctagttt caaactgcca gtatttttcc     2340

ttttgctttt aaaatagtta caatattttt catgatagcc acagtattgc cacagtttat     2400

tataataaag ggtttttatt tgatttagcg cattcaaagc ttttttctat cacttttgtg     2460

ttcagaatat aacctttgtg tgcgtgtatg ttgtgtgtgt gcatgtgtgg cgtatatgtg     2520

tgttacaggt taatgccttc ttggaattgt gttaatgttc tcttggttta ttatgccatc     2580

agaatggtaa atgagaacac tacaactgta gtcagctcac aatttttaaa taaaggatac     2640

cacagtgcat gctgtttgtt caaaaaaaaa aaaaaaaaa                            2679


<210>  1063
<211>  3111
<212>  DNA
<213>  homo sapiens

<400>  1063
aaatattctt gcttgagtaa accacagtaa gaataaggaa gtagtgactg agtgccttgc       60

cagtacagca gatgctagaa cataatgtag cattactttc cccagggttt attgttatgt      120

aagttcttgt tcagcttcct ttgttttctt tcacttctga gaatttaact ttcgtttctc      180

actcagctcc tgtggggaaa ctcatttgtg gagaccagcc ctctggcttg gtgagtgaat      240

ctggtttaca ccggctcctg ccctgccttc actcttctcc cctgattcaa gactcctctg      300

ctttggactg aagcactgca ggagtttgtg accaagaact tcaagagtca agacagaagg      360

aagccaaggg agcagtgcaa tggatttctc agtaaaggta gacatagaga aggaggtgac      420

ctgccccatc tgcctggagc tcctgacaga acctctgagc ctagattgtg gccacagctt      480

ctgccaagcc tgcatcactg caaagatcaa ggagtcagtg atcatctcaa gaggggaaag      540

cagctgtcct gtgtgtcaga ccagattcca gcctgggaac ctccgaccta atcggcatct      600

ggccaacata gttgagagag tcaaagaggt caagatgagc ccacaggagg ggcagaagag      660

agatgtctgt gagcaccatg gaaaaaaact ccagatcttc tgtaaggagg atggaaaagt      720

catttgctgg gtttgtgaac tgtctcagga acaccaaggt caccaaacat tccgcataaa      780

cgaggtggtc aaggaatgtc aggaaaagct gcaggtagcc ctgcagaggc tgataaagga      840

ggatcaagag gctgagaagc tggaagatga catcagacaa gagagaaccg cctggaagaa      900

ttatatccag atcgagagac agaagattct gaaagggttc aatgaaatga gagtcatctt      960

ggacaatgag gagcagagag agctgcaaaa gctggaggaa ggtgaggtga atgtgctgga     1020

taacctggca gcagctacag accagctggt ccagcagagg caggatgcca gcacgctcat     1080

ctcagatctc cagcggaggt tgaggggatc gtcagtagag atgctgcagg atgtgattga     1140

cgtcatgaaa aggagtgaaa gctggacatt gaagaagcca aaatctgttt ccaagaaact     1200

aaagagtgta ttccgagtac cagatctgag tgggatgctg caagttctta aagagctgac     1260

agatgtccag tactactggg tggacgtgat gctgaatcca ggcagtgcca cttcgaatgt     1320

tgctatttct gtggatcaga gacaagtgaa aactgtacgc acctgcacat ttaagaattc     1380

aaatccatgt gatttttctg cttttggtgt cttcggctgc caatatttct cttcggggaa     1440

atattactgg gaagtagatg tgtctggaaa gattgcctgg atcctgggcg tacacagtaa     1500

aataagtagt ctgaataaaa ggaagagctc tgggtttgct tttgatccaa gtgtaaatta     1560

ttcaaaagtt tactccagat atagacctca atatggctac tgggttatag gattacagaa     1620

tacatgtgaa tataatgctt ttgaggactc ctcctcttct gatcccaagg ttttgactct     1680

ctttatggct gtgcctccct gtcgtattgg ggttttccta gactatgagg caggcattgt     1740

ctcatttttc aatgtcacaa accacggagc actcatctac aagttctctg gatgtcgctt     1800

ttctcgacct gcttatccgt atttcaatcc ttggaactgc ctagtcccca tgactgtgtg     1860

cccaccgagc tcctgagtgt tctcattcct ttacccactt ctgcatagta gcccttgtgc     1920

tgagactcag attctgcacc tgagttcatc tctactgaga ccatctcttc ctttctttcc     1980

ccttctttta cttagaatgt ctttgtattc atttgctagg gcttccatag caaagcatca     2040

tagattgctg atttaaactg taattgtatt gccgtactgt gggctggaaa tcccaaatct     2100

agattccagc agagttggtt ctttctgagg tctgcaagga agggctctgt tccatgcctc     2160

tctccttggc ttgtagaagg catcttgtcc ctatgactct tcacattgtc tttatgtaca     2220

tctctgtgcc caagttttcc ctttttatta agacaccagt catactggct cagggcccac     2280

cgctaatgcc ttaatgaaat cattttaaca ttatattctc tacaaagacc ttatttccaa     2340

ataagataat atttggaggt attgggaata aaaactccaa catataaatt tgaggaaggc     2400

acgatttcac tcataacaat cttacccttt cttgcaagag atgcttgtac attattttcc     2460

taataccttg gtttcactag tagtaaacat tattattttt tttatatttg caaaggaaac     2520

atatctaatc cttcctatag aaagaacagt attgctgtaa ttccttttct tttcttcctc     2580

atttcctctg ccccttaaaa gattgaagaa agagaaactt gtcaactcat atccacgtta     2640

tctagcaaag tacataagaa tctatcacta agtaatgtat ccttcagaat gtgttggttt     2700

accagtgaca ccccatattc atcacaaaat taaagcaaga agtccatagt aatttatttg     2760

ctaatagtgg atttttaatg ctcagagttt ctgaggtcaa attttatctt ttcacttaca     2820

agctctatga tcttaaataa tttacttaat gtattttggt gtattttcct caaattaata     2880

ttggtgttca agactatatc taattcctct gatcactttg agaaacaaac ttttattaaa     2940

tgtaaggcac ttttctatga attttaaata taaaaataaa tattgttctg attattactg     3000

aaaagatgtc agccatttca atgtcttggg aaacaatttt ttgtttttgt tctgttttct     3060

ttttgcttca ataaaacaat agctggctct aaaaaaaaaa aaaaaaaaaa a              3111


<210>  1064
<211>  5913
<212>  DNA
<213>  homo sapiens

<400>  1064
gtggacgcag cgggctttgg aaaggcccca agttaatgag gcgtgcgccg gctgccgagc       60

gcctcttgga gctgggcttt cccccgcggt gcgggcgcca ggagccgcct tttccgctgg      120

gtgtcactcg ggggtgggga agatggccca ttcaaaagcg ccgcgagggg gcccggccag      180

tgcccttcag tgagcgctcg caagaggacg gcagaggccc ggcagctcgg agctccggga      240

ccttgtggcg catcaggacg cggctgtccc tctgccggga cccagagccg ccgccgccgc      300

tctgcctcct gcgtgttagc ctcctctgcg cgctccgggc aggcggccgt gggagccgct      360

ggggcgagga cggcgcgagg ctgctgctgc tgcccccggc ccgcgcggct ggaaacggag      420

aggccgagcc aagcggcggc ccctcttatg ctgggaggat gctggagagt agcggctgca      480

aagcgctgaa ggagggcgtg ctggagaagc gcagcgacgg gttgttgcag ctctggaaga      540

aaaagtgttg catcctcacc gaggaagggc tgctgcttat cccgcccaag cagctgcaac      600

accagcagca gcagcagcaa cagcagcagc agcagcagca acaacagccc gggcaggggc      660

cggccgagcc gtcccaaccc agtggccccg ctgtcgccag cctcgagccg ccggtcaagc      720

tcaaggaact gcacttctcc aacatgaaga ccgtggactg tgtggagcgc aagggcaagt      780

acatgtactt cactgtggtg atggcagagg gcaaggagat cgactttcgg tgcccgcaag      840

accagggctg gaacgccgag atcacgctgc agatggtgca gtacaagaat cgtcaggcca      900

tcctggcggt caaatccacg cggcagaagc agcagcacct ggtccagcag cagcccccct      960

cgcagccgca gccgcagccg cagctccagc cccaacccca gcctcagcct cagccgcaac     1020

cccagcccca atcacaaccc cagcctcagc cccaacccaa gcctcagccc cagcagctcc     1080

acccgtatcc gcatccacat ccacatccac actctcatcc tcactcgcac ccacaccctc     1140

acccgcaccc gcatccgcac caaataccgc acccacaccc acagccgcac tcgcagccgc     1200

acgggcaccg gcttctccgc agcacctcca actctgcctg aaaggggcag ctcccgggca     1260

agacaaggtt ttgaggactt gaggaagtgg gacgagcaca tttctattgt cttcacttgg     1320

atcaaaagca aaacagtctc tccgccccgc accagatcaa gtagtttgga catcacccta     1380

ctgaaaactt gcgattcttc ttagttttct gcatactttt catcacgatg caggaaacga     1440

tttcgagtca agaagacttt tatttatgaa cctttgaaag gatcgtcttg tatggtgaat     1500

tttctaggag cgatgatgta ctgtaatttt attttaatgt attttgattt atgattattt     1560

attagttttt ttttaaatgc ttgttctaag acatttctga atgtagacca ttttccaaaa     1620

aggaaacttt attttcaaaa acctaatccg tagtaattcc taatcttgga gaataaaaaa     1680

gggcggtgga ggggaaaaca ttaagaattt attcattatt tctcgagtac tttcagaaag     1740

tctgacactt tcattgttgt gccagctggt tgaaattaaa actctgatat tacttttttt     1800

gaggattttt atttttgttt ttgcttaaac atatagtttg tctagaagtt taaaaagcta     1860

aaagttaaaa atggtgtaat tatgaaaatc taacactcaa gatagtttct aaaaggaaat     1920

cagtagttaa ggatacctga tttcaaaata tttaaagcat aacctaactg atggtaggat     1980

gattgtatct tgaatatgtg gtagggccac atctattgta ggaaaacctt gcttttatca     2040

tctgtgtgta aagggcttaa taaggagaag aggccttttg actgatttgt gagtataaat     2100

gcatttgctg tttcatttca aaaatgttgt ggaggaaaag agtacattta acttgtataa     2160

gagaatattt gtactcctgt ccaggctgca ggacctttct tcgagagctt tgcacacttg     2220

acttgaacca cattttctga tccctttact ttgttttaga agcacactga aaaatctcgt     2280

tgtttaaagt acaatttgta aatatttcaa aggtctagga gtcataactt ttgttttcat     2340

actgaaaatg atgttgatca gagaaaccaa ctgttttgct tttcattgct ctgtgagaaa     2400

tttgaggatt ctgttttgct gttaggtaag ctaaactcag aaattgaaaa ggaaaagact     2460

ggataaacac aggattttca gtaagaaaac aaccccagtc ttgtcttaga agccacttgt     2520

tgaggagtct gttgggggaa aaaagaggat atgcttttaa aggtagaaca aaccttcttc     2580

tgtgttaaat caaaaggatg ttcaaaatcc accaggacag atgctacttg ggtttaaatg     2640

gagccataga tgatacaaag tcctcttggg gctgaaaatc acttcctatt tgcatggctt     2700

tactaactgg tttctgtttt ccattatctt tttcacagaa agtcttggtc agtatttttc     2760

cagcatttaa attgaaacgg tcagtattag accactgcta ggttatgtag tcaagaaata     2820

aaaatagaat tacatgctac agatgtcttt attctccttc catctagaaa ggagttccaa     2880

ggtcaaatta ctttttagtg caatagttaa atgacatttt gagatcataa ctcatatcca     2940

aaaagttgca gggaaaatta aaatagcttt cccctattaa gctaatggca aacaaaactt     3000

aagtggaccc ccacttccag tggttgttta ggttgcagtt gtgaaaatat gctgccaaca     3060

tttaaaaact tgtttcatat gtatatatgt atacacatat atgaatatgt atgtatatat     3120

acatatatga gaacatgtgt gtacacatat atgaatatgt atatatgtgt atgtatgtat     3180

atatgtatat gaaatgagag ccacatctaa agatttctta aatcaagttt ggttcagctt     3240

ccttagaact gtggctgtac tttttgagga gtacctcata gtactatatt tttaatgcat     3300

gcaaatcata atagctccaa atgaaccaca gttttttccc aatggaggat ttttttttaa     3360

ttcttgtact aaaaaaaaaa aatccatacc aaatattttt acaaattaag attgatgtag     3420

gttttaaaaa aggcatttgt atgttgttag cttacatatg gggctaggta atttcattgc     3480

ttaaaaagat gcgcctaggc tccctcttgg tggctggatt tctttttctt cgcccgtggt     3540

ggccatggtt cttaataggg ccaccggaat catggtttct tttttttttt ttttttttga     3600

gatggagtct cgccctgtga cccaggctgg agtgcagtgg cacgatctcg gctcactgca     3660

acctctgcct cctgggttca cgccattctc ctgtctcagc ctcctgagta gctgggacta     3720

caggtgaatg ccaccacgcc cggctgattt ttgtattttt agtagagatg gggtttcacc     3780

atagtggtca ggctgttctc gaactcctga cctcaggtga tccacctgcc ttggcctccc     3840

aaagtgctag gattacaggt gtgagccacc acacccggcc ccagaataat ggtttcttga     3900

ctttctgtag cccttgttcc ttagtctgct gtgatattta tgttgacctt tatcattttc     3960

tattctgaac ccctcttagc atttaatgtg aaatctaaga aattagaagt agaatggctt     4020

ttattgtttt gacacctttg aaattattat taataatttt tccagagcaa aaaagcaaac     4080

acgctcaata agactaaaca aaacaaaata taaatgtaca tcatttaatg tcccagtggc     4140

tctattctac ctgtaagaaa atgatacaaa accacctaag atattttgaa gcctgacaaa     4200

tcagcttcat ggaaaaaggt aaaaaatgca tttttcaacc gaaagggcag atccaataga     4260

agacccgctc cttaaataaa cataaaatgt aaaaagttgg aaaattaaga gtaatgttcc     4320

atctggaaac tgaacttttg tccttgaact tgtgttggca ccaagcctca tacacagtga     4380

gctcaataac tgttgggaca aaggaaggaa ggacaaaatg tgtaacttcc cagcatctgg     4440

gagatgctgt ctcttgcctc actgagtgtt ccttttcttt gctctcatgt cattccctga     4500

gaacaatgaa ttctgggaca ggctaaacat catgatgaag tttcttaaac agactttctt     4560

agtggaaatc catttagatc tgggtgtgct ctatggggag tgctgacgtc aaagagcaaa     4620

tgtctataag gggccctttt aaaatgaaca ttttcctcat tgagcaagct gggattctct     4680

aatgtagaaa tcaagccatc tttataattt cacttcagat gtttatgttt ttgttttttt     4740

tgtctccaat gatggtaaaa ataaaaacta cgcattactt aaaggagttt ccctcacatg     4800

taaacactgt taggaagtct ggattaagtt gaaagtcctg ttttaacttt ttttctctca     4860

tataccaaac actctgtatt tctcttaaag aagcccttta agagaaagcc ctaattttat     4920

atctgacagt aaagtttgct gcaagtgtat gagttcaaac acatcccttg ttttctgtcc     4980

ctaggggaaa agtcatgtag ttttagcttg gctccagtgt taatattata ttcagtagca     5040

gccttagaag agtggtctaa gacttgaacc tggagcaatt ttatagcaca gaatcctacg     5100

aagataggac tgtgaacatt tgttttcttt ttcgtgtgtg tcaaactaac tggtttttgc     5160

tttaccaata aaatgtcctc ggcagagtaa attttaaacg tgaaaattat agatcttgat     5220

attgaatcca tcagtgattc aagagataca cctatttgcc taaaacaacc taagatgtat     5280

tggttatgga atcatgtgtt ggataggttc ttaagacctg tttcctcaaa tcttgacaca     5340

gttttcaagg gtggcttatt gacttgcacg gttgggcaga taatccagat ttacctaaga     5400

ttgggtaaaa aagtcatctg tgactttgct ggcagggcat ttgctaagtg gagtacagga     5460

tctaaaaggg ttttcttaga aagggcaata ttgtccaatg aagtaagcag aaggactctg     5520

ggttagaagc atctgcacaa aaactggtga gacctactct ccactgctct gcagctggat     5580

ggctgatggc aggctgagca gtggggaagc aggttttaac aacagggagt ccttccaggt     5640

cactgtatat tgagaagaaa cataaaacta ttgtctgtta cattccgagg tcagccttct     5700

tcttaacgtt ttataatatg caaatgccag cttctggaaa gcaagtatca tcatgtacca     5760

aatgctttat acaccatcac attcatgaat tttttagcat ggtcagaact tgtgtaaata     5820

tgtctcttag atgattttgg ggagatgtga tttatttttc atattttcaa aatgcatttc     5880

atttcaaata aagttatcta ttgagacaac cga                                  5913


<210>  1065
<211>  1144
<212>  DNA
<213>  homo sapiens

<400>  1065
ttcccacgcg ccggccccgt tgcccccgcg cgcgcgcaca ctcgcgagcc ccggcgacat       60

gcaaatgagc tggctccagt gcccagaccc aagcccccca ctgctcaatg gacaccccca      120

gcccagaccc gttgccttcg cctttgcccg gggaggaaga gaaacctctg gccttatctc      180

ctcctgttcc ccggggccgc cgaggccgtc gtcctggggg agccacctcc tcaaatcgga      240

cactcaaggc ctccctccct cgcaagcggg gccgcccccc caagtcaggg caggagcccc      300

cactggtgca ggtgcagggg gtgacagccc cagtaggcag cagtggcggg agcgacctcc      360

tcctgatcga tgatcagggt gtgccctata cggtctctga aggttcagcg gctgggcctg      420

agggctctgg ccccaggaag gccccacact tctgcccggt gtgcctgcgg gccttcccct      480

acctctccga cctggagcgc cacagcatct cgcactcaga gctgaagccg caccagtgca      540

aggtttgcgg caagaccttc aagcgctcca gccacctgcg gcggcactgc aacatccatg      600

ccggcctgcg gcccttccgc tgcccgctgt gcccccgccg cttccgcgag gcgggcgagc      660

tggcgcacca ccaccgcgtg cactcggggg agcgcccgta ccagtgcccc atctgccggc      720

tgcgctttac agaggccaac acgctccggc gccatgcgaa gcgcaagcac ccggaggcca      780

tgggggtacc cctgtgtgca ccagatccag ggtctgaacc gccgtgggac gaggagggca      840

tcccggccac agcaggggcc gaggaggagg aggagacaga ggggaaaggg gagccggcct      900

gacccacacc cccggccatc gctccctggg ccaggtttag agcagggagt ttggctggtg      960

ctgggcctga gccagggggc cgggacaccc ttgtttccgg tggtcttccc gttgtgggag     1020

caggtggagg gtggagacct aaactttggg gtccagctgc cttcagcccc cctcccccag     1080

actaacagac ccttggaggc aggggctgtg gaaataaatc tctgcctgct ggcaaaaaaa     1140

aaaa                                                                  1144


<210>  1066
<211>  4569
<212>  DNA
<213>  homo sapiens

<400>  1066
tcttgttgtt acgggtaacg gaagtgtggc ggcgttgggt tgagcgggct ttttggaagt       60

ttgtggcgga gttctgtgat atgagcaaca atggaccaga agattttatc tctagcagca      120

gaaaaaacag cagacaaact gcaagaattt cttcaaaccc tgagagaagg tgatttgact      180

aatctccttc agaatcaagc agtgaaagga aaagttgctg gagcactcct gagagccatc      240

ttcaaaggtt ccccctgctc tgaggaagct ggaacactta ggagacgtaa gatatacact      300

tgttgtatcc agttggtgga atcgggggat ttgcagaaag aaatagcgtc tgagatcata      360

ggattactga tgctggaggc tcaccatttt ccaggaccat tattggttga attagccaat      420

gagtttatta gtgctgtcag agaaggcagc ctagtgaatg gaaaatcttt ggagttacta      480

cctatcattc tcactgccct ggctacgaaa aaggaaaatc tggcttatgg aaaaggtgta      540

ctgagtgggg aagaatgtaa gaaacagttg attaacaccc tgtgttctgg caggtgggat      600

cagcaatatg taatccaact cacctccatg ttcaaggatg tccctctgac tgcagaagag      660

gtggaatttg tggtggaaaa agcattgagc atgttctcca agatgaatct tcaagaaata      720

ccacctttgg tctatcagct tctggttctc tcctccaagg gaagcagaaa gagtgttttg      780

gaaggaatca tagccttctt cagtgcacta gataagcagc acaatgagga acagagtggt      840

gacgagctat tggatgttgt cactgtgcca tcaggtgaac ttcgtcatgt ggaaggcacc      900

attattctac acattgtgtt tgccatcaaa ttggactatg aactaggcag agaactcgtg      960

aaacacttaa aggtaggaca gcaaggagat tccaataata acttaagtcc cttcagcatt     1020

gctcttcttc tgtctgtaac aagaatacaa agatttcagg accaggtgct tgatctttta     1080

aagacttcgg ttgtaaagag ctttaaggat cttcaactcc tccaaggctc aaaatttctt     1140

cagaatctag ttcctcatag atcttatgtt tcaaccatga tcttggaagt agtgaagaat     1200

agcgttcata gctgggacca tgttactcag ggcctcgtag aacttggttt cattttgatg     1260

gattcatatg ggccaaagaa ggttcttgat ggaaaaacta ttgaaaccag cccaagtctt     1320

tctagaatgc caaaccagca tgcatgtaag ctcggagcta atatcctgtt ggaaactttt     1380

aagatccatg agatgatcag acaagaaatt ttggagcagg tcctcaacag ggttgttacc     1440

agagcatctt ctcccatcag tcatttctta gacctgcttt caaatatcgt catgtatgca     1500

cccttagttc ttcaaagttg ttcttctaaa gtcacagaag cttttgacta tttgtccttt     1560

ctgccccttc agactgtaca aaggctgctt aaggcagtgc agccccttct caaagtcagc     1620

atgtcaatga gagactgctt gatacttgtc cttcggaaag ctatgtttgc caaccagctt     1680

gatgcccgaa aatctgcagt tgctgggttt ttgctgctcc tgaagaactt taaagtttta     1740

ggcagcctgt catcctctca gtgcagtcag tctctcagtg tcagtcaggt tcatgtggat     1800

gttcacagcc attacaattc tgtcgccaat gaaacttttt gccttgagat catggatagt     1860

ttgaggagat gcttaagcca gcaagctgat gttcgactca tgctttatga ggggttttat     1920

gatgttcttc gaaggaactc tcagctggct aattcagtca tgcaaactct gctctcacag     1980

ttaaaacagt tctatgagcc aaaacctgat ctgctgcctc ctctgaaatt agaagcttgt     2040

attctgaccc aaggagataa gatctctcta caagaaccac tggattatct gctgtgttgt     2100

attcagcatt gtttggcctg gtataagaat acagtcatac ccttacagca gggagaggag     2160

gaagaggagg aggaagaggc attctacgaa gacctagatg atatattgga gtccattact     2220

aatagaatga ttaagagtga gctggaagac tttgaactgg ataaatcagc agatttttct     2280

cagagcacca gtattggcat aaaaaataat atctgtgctt ttcttgtgat gggagtttgt     2340

gaggttttaa tagaatacaa tttctccata agtagtttca gtaagaatag gtttgaggac     2400

attctgagct tatttatgtg ttacaaaaaa ctctctgaca ttcttaatga aaaagcgggt     2460

aaagccaaaa ctaaaatggc caacaagaca agtgatagtc ttttgtccat gaaatttgtg     2520

tccagtcttc tcactgctct tttcagagtc ttgctatgga gatacacttc aattcctact     2580

tcagtggaag agtcgggaaa gaaagagaaa ggaaagagca tctcactgct gtgcttggag     2640

ggtttacaga aaatattcag tgctgtgcaa cagttctatc agcccaagat tcagcagttt     2700

ctcagagctc tggatgtcac agataaggaa ggagaagaga gagaagatgc agatgtcagt     2760

gtcactcaga gaacagcatt ccagatccgg caatttcaga ggtccttgtt gaatttactt     2820

agcagtcaag aggaagattt taatagcaaa gaagccctcc tgctagtcac ggttcttacc     2880

agtttgtcca agttactgga gccctcctct cctcagtttg tgcagatgtt atcctggaca     2940

tcaaagattt gcaaggaaaa cagccgggag gatgccttgt tttgcaagag cttgatgaac     3000

ttgctcttca gcctgcatgt ttcgtataag agtcctgtca ttctgctgcg tgacttgtcc     3060

caggatatcc acgggcatct gggagatata gaccaggatg tagaggtgga gaaaacaaac     3120

cactttgcaa tagtgaattt gagaacggct gcccccactg tctgtttact tgttctgagt     3180

caggccgaga aggttctaga agaagtggac tggctaatca ccaagcttaa gggacaagtg     3240

agccaagaaa ccttatcaga agaggcctct tctcaggcaa ccctaccaaa tcagcctgtt     3300

gagaaagcta tcatcatgca actgggaact ctgcttacat ttttccacga gctggtgcag     3360

acagctctgc catcaggcag ctgtgtggac accttgttaa aggacttgtg caaaatgtac     3420

accacactta cagcccttgt cagatattat ctccaggtgt gtcagagctc cggaggaatt     3480

ccaaaaaata tggaaaagct ggtgaagctg tctggttctc atctgacccc cctgtgttat     3540

tctttcattt cttacgtaca gaataagagt aagagcctga actatacggg agagaaaaag     3600

gagaaacctg ctgccgttgc cacagccatg gccagagttc ttcgggaaac caagccaatc     3660

cctaacctca tctttgccat agaacagtat gaaaaatttc tcatccacct ttctaagaag     3720

tccaaggtga acctgatgca gcacatgaag ctcagcacct cacgagactt caagatcaaa     3780

ggaaacatcc tagacatggt tcttcgagag gatggtgaag atgaaaatga agagggcact     3840

gcatcagagc atgggggaca gaacaaagaa ccagccaaga agaaaaggaa aaaataaatg     3900

aaatgcctga gttaatgtga actttggggc ttctgcttca tttttaccca acaagcaaca     3960

atgccccttg tcctgtagtc cacaccgatg ttggcatctt ggttctgaac ccactgaatt     4020

caactgcacc ttcagttaga aggaatcttc ttggcaggtc ctgctactga aaaatggctg     4080

gccttaggca agcccttttg caaaaagcac agctgaaagc ctgagtttgg gagcctgcac     4140

caccccgatg aagctccacg ggagcaaata cagagcctcc aggcagtgct atggtccagg     4200

ctggcttcgt ttttccaagg agcctttggt gagttcaatt atctggtaaa tatccagcgc     4260

ttcacctgaa agatagtgca aattggttag gatgccacct caagaactgt aactgagagc     4320

tcagaagtga gcaaaggagc ttaatgctaa ggtcaaaagg agagtgaaag gttgagaaca     4380

attgccacga acggtaatgt tacatgttag gagggtctgt tttcttttta tataagtgtg     4440

tcttagatat attttaaata gaaaataagc tttctgattt acttgtttgg tatttaaagc     4500

acagtttgtt tttctgtcac ctatagagtg caagaatgca ctctatagaa taaattatct     4560

ttaaacatt                                                             4569


<210>  1067
<211>  3027
<212>  DNA
<213>  homo sapiens

<400>  1067
gggatatgta gtgcgtgact tccgcagtgc acgctgcgcc tgccgggcat tttttcctgg       60

tttgggggca aggtctcatg ggaaaggtca tgtctctcga agaaaggtta taaaccctga      120

gatatgaggg ttgggcgaga catccgagcc tgtttcgttc cgtgttggga ccaggaataa      180

ccctgacttc tgagctttca taaccccagg atcctccaga aaatttgcgg cgcgctgagg      240

gaaaaccttg ctgaagctgt acattggaat gcgtttacag tcattgtaat ggaagcaaaa      300

tacatgaagg aaaaactgtt atttgtatcc ctgcttattg cacctgacga ctagttgcag      360

atggttttgt ttacctaaga aaacttgtga tataaatgaa aaaaacacct gttttcctag      420

agtcattggt tacaaatatg cttcgtctaa gagctatttg tccattctcc tggagagtgt      480

ttcaatttcg acccatcagt tgtgaaccac taattattca gatgaataag tgtacagatg      540

aggagcaaat gtttggtttt attgaaagaa acaaagccat actttcagaa aagcaagtgg      600

gatgtgcatt tgatatgctt tggaagcttc aaaagcagaa gaccagcctg ttaaaaaatg      660

ctgagtatgt cagagaccat cctcaatttc ttactcttca taatttagct acaaataaat      720

tcaaattaat gaatgacgat accctggtga atgtgttata cgtcacacaa cagtttgctg      780

gtgaggccca tgacccgcta gttgaagcac tagttacaga agcatggaga aggctagaaa      840

ggtttgatat taaactgctc tcagaatttt cctcttgcct agcagatcag catttgtatt      900

ttagtccatt aatgggaaaa atagctgata ttgttcatag gaacttggaa accacacagg      960

acttaagttc cttgtctgtc ttgatggtca acatatcttc tttaatatca cgacattttc     1020

aacaacaact ggtgaacaaa acagaacttc tttttgacac catagattct tctgaggtca     1080

acgttgcaaa aagcatagca aagtttcttc gaaatgttag atatcgttat caaccactat     1140

tagaaagatg taataacgta tttttaagta atgtggacca ccttgatttg gattccatca     1200

gtaaaatact tagtgtatac aaatttctac aatttaatag ttttgaattt attataatgg     1260

ctaaaaagaa gctaactgaa atgattcctc tgtgtaatca tcctgctagc tttgtaaaat     1320

tgtttgtagc attgggaccc attgcaggac ctgaagaaaa gaaacaactt aaatcaacta     1380

tgttattgat gtcagaggac ctaactggcg agcaagccct ggcagtgttg ggagcaatgg     1440

gagatatgga aagcagaaac tcatgtctga ttaaaagagt tacttcagtt ctgcataaac     1500

atttggatgg ctataaacca ttagagttgt tgaagataac tcaagaatta acttttctgc     1560

atttccaaag gaaggagttt tttgcgaaac ttagagaatt actgcttagt tatttgaaaa     1620

atagtttcat accaactgag gtgtctgttc tggtccgtgc tatttccctg ctcccttctc     1680

ctcacttgga cgaagtgggg atatcccgaa ttgaagccgt tttaccacag tgtgacctaa     1740

ataacctgag tagttttgcc acatctgttt taagatggat tcagcatgat cacatgtatt     1800

tggataatat gactgcgaaa caactgaaac tacttcaaaa attagatcac tatggtcgtc     1860

agagactaca acacagcaac agtttggatc tgttacggaa ggaacttaaa tctctcaaag     1920

gaaacacgtt tcctgagtca cttcttgaag aaatgattgc tactttacag catttcatgg     1980

atgatattaa ttacataaat gttggggaga ttgcatcttt tatttctagt actgattacc     2040

tcagtacttt gctactagat aggatagcct cagtggctgt tcagcagatt gaaaagatcc     2100

atccttttac aatccctgct attattcgtc cattcagcgt attgaactat gatccacctc     2160

aaagggatga atttttggga acttgcgtgc aacatcttaa ttcttactta ggtatattgg     2220

atccttttat attagtgttt cttggtttct ctttggccac acttgaatat tttccagaag     2280

atctgctaaa ggcaattttt aacatcaaat tcttagctag attggattct caacttgaaa     2340

ttttatctcc atctcgaagt gcaagagtcc agtttcatct tatggagtta aatagatcag     2400

tctgcttgga atgccctgag tttcagattc catggtttca tgaccgcttc tgtcaacaat     2460

ataataaagg tattggtggc atggatggaa cacaacagca gatttttaaa atgttagcag     2520

aggtactagg aggaatcaat tgtgtaaaag cctcggttct tacgccttat taccacaaag     2580

tagattttga gtgtatcttg gataaaagaa aaaaacctct tccgtatgga agccataata     2640

tagcattggg acaactacca gaaatgccct gggaatcaaa tatcgaaata gttggatcaa     2700

ggctgccacc aggggctgaa aggattgctt tggaattttt ggattcaaaa gcactttgta     2760

gaaatatccc tcacatgaaa ggaaaatctg ctatgaaaaa acgacatttg gaaattctgg     2820

ggtatcgtgt aattcagatt tcccagtttg aatggaactc tatggcactg tcaacaaagg     2880

atgctcggat ggactacctg agagaatgta tatttggaga agtcaagtca tgtttgtagt     2940

ttttatttaa aatgaatgtt atcgtgtgtt acatttggac ctattttaat aaagtggcct     3000

gtctcaatta aaaaaaaaaa aaaaaaa                                         3027


<210>  1068
<211>  5336
<212>  DNA
<213>  homo sapiens

<400>  1068
gcggccgcgg cggcgggagg cggcgggagg cgggcggagg aggaggcgga ggaggcggga       60

gctgagctga gtggggcggg cggcggcggg gcccgagccg gagaagatgg cggtgcggaa      120

gaaggacggc ggccccaacg tgaagtacta cgaggccgcg gacaccgtga cccagttcga      180

caacgtgcgg ctgtggctcg gcaagaacta caagaagtat atacaagctg aaccacccac      240

caacaagtcc ctgtctagcc tggttgtaca gttgctacaa tttcaggaag aagtttttgg      300

caaacatgtc agcaatgcac cgctcactaa actgccgatc aaatgtttcc tagatttcaa      360

agcgggaggc tccttgtgcc acattcttgc agctgcctac aaattcaaga gtgaccaggg      420

atggcggcgt tacgatttcc agaatccatc acgcatggac cgcaatgtgg aaatgtttat      480

gaccattgag aagtccttgg tgcagaataa ttgcctgtct cgacctaaca tttttctgtg      540

cccagaaatt gagcccaaac tactagggaa attaaaggac attatcaaga gacaccaggg      600

aacagtcact gaggataaga acaatgcctc ccatgttgtg tatcctgtcc cggggaatct      660

agaagaagag gaatgggtac gaccagtcat gaagagggat aagcaggttc ttctgcactg      720

gggctactat cctgacagtt acgacacgtg gatcccagcg agtgaaattg aggcatctgt      780

ggaagatgct ccaactcctg agaaacctag gaaggttcat gcaaagtgga tcctggacac      840

cgacaccttc aatgaatgga tgaatgagga agactatgaa gtaaatgatg acaaaaaccc      900

tgtctcccgc cgaaagaaga tttcagccaa gacactgaca gatgaggtga acagcccaga      960

ttcagatcga cgggacaaga aggggggaaa ctataagaag aggaagcgct ccccctctcc     1020

ttcaccaacc ccagaagcaa agaagaaaaa tgctaagaaa ggtccctcaa caccttacac     1080

taagtcaaag cgtggccaca gagaagagga gcaagaagac ctgacaaagg acatggacga     1140

gccctcacca gtccccaatg tagaagaggt gacacttccc aaaacagtca acacaaagaa     1200

agactcagag tcggccccag tcaaaggcgg caccatgacc gacctggatg aacaggaaga     1260

tgaaagcatg gagacgacgg gcaaggatga ggatgagaac agtacgggga acaagggaga     1320

gcagaccaag aatccagacc tgcatgagga caatgtgact gaacagaccc accacatcat     1380

cattcccagc tacgctgcct ggtttgacta caatagtgtt catgccattg agcggagggc     1440

tctccccgag ttcttcaacg gcaagaacaa gtccaagact ccagagatct acctggccta     1500

tcgaaacttt atgattgaca cttaccgact gaacccccaa gagtatctta cctctaccgc     1560

ctgccgccga aacctagcgg gtgatgtctg tgccatcatg agggtccatg ccttcctaga     1620

acagtggggt cttattaact accaggtgga tgctgagagt cgaccaaccc caatggggcc     1680

tccgcctacc tctcacttcc atgtcttggc tgacacacca tcagggctgg tgcctctgca     1740

gcccaagaca cctcagggcc gccaggttga tgctgatacc aaggctgggc gaaagggcaa     1800

agagctggat gacctggtgc cagagacggc taagggcaag ccagagctgc agacctctgc     1860

ttcccaacaa atgctcaact ttcctgacaa aggcaaagag aaaccaacag acatgcaaaa     1920

ctttgggctg cgcacagaca tgtacacaaa aaagaatgtt ccctccaaga gcaaggctgc     1980

agccagtgcc actcgtgagt ggacagaaca ggaaaccctg cttctcctgg aggcactgga     2040

aatgtacaaa gatgactgga acaaagtgtc cgagcatgtg ggaagccgca cacaggacga     2100

gtgcatcttg cattttcttc gtcttcccat tgaagaccca tacctggagg actcagaggc     2160

ctccctaggc cccctggcct accaacccat ccccttcagt cagtcgggca accctgttat     2220

gagcactgtt gccttcctgg cctctgtcgt cgatccccga gtcgcctctg ctgctgcaaa     2280

gtcagcccta gaggagttct ccaaaatgaa ggaagaggta cccacggcct tggtggaggc     2340

ccatgttcga aaagtggaag aagcagccaa agtaacaggc aaggcggacc ctgccttcgg     2400

tctggaaagc agtggcattg caggaaccac ctctgatgag cctgagcgga ttgaggagag     2460

cgggaatgac gaggctcggg tggaaggcca ggccacagat gagaagaagg agcccaagga     2520

accccgagaa ggagggggtg ctatagagga ggaagcaaaa gagaaaacca gcgaggctcc     2580

caagaaggat gaggagaaag ggaaagaagg cgacagtgag aaggagtccg agaagagtga     2640

tggagaccca atagtcgatc ctgagaagga gaaggagcca aaggaagggc aggaggaagt     2700

gctgaaggaa gtggtggagt ctgaggggga aaggaagaca aaggtggagc gggacattgg     2760

cgagggcaac ctctccaccg ctgctgccgc cgccctggcc gccgccgcag tgaaagctaa     2820

gcacttggct gctgttgagg aaaggaagat caaatctttg gtggccctgc tggtggagac     2880

ccagatgaaa aagttggaga tcaaacttcg gcactttgag gagctggaga ctatcatgga     2940

ccgggagcga gaagcactgg agtatcagag gcagcagctc ctggccgaca gacaagcctt     3000

ccacatggag cagctgaagt atgcggagat gagggctcgg cagcagcact tccaacagat     3060

gcaccaacag cagcagcagc caccaccagc cctgccccca ggctcccagc ctatcccccc     3120

aacaggggct gctgggccac ccgcagtcca tggcttggct gtggctccag cctctgtagt     3180

ccctgctcct gctggcagtg gggcccctcc aggaagtttg ggcccttctg aacagattgg     3240

gcaggcaggg tcaactgcag ggccacagca gcagcaacca gctggagccc cccagcctgg     3300

ggcagtccca ccaggggttc ccccccctgg accccatggc ccctcaccgt tccccaacca     3360

acaaactcct ccctcaatga tgccaggggc agtgccaggc agcgggcacc caggcgtggc     3420

ggacccaggc acccccctgc ctccagaccc cacagccccg agcccaggca cggtcacccc     3480

tgtgccacct ccacagtgag gagccagcca gacatctctc cccctcaccc cctgtggaca     3540

tcacggttcc aggaacagcc cttcccccac cactgggacc ctccccagcc tggagagttc     3600

atcactacgt aaggaaagct ccttccgccc ctccaaagcc ctcaccatgc ctaacagagg     3660

catgcatttt tatatcagat tattcaagga cttctgttta aaagatgttt ataatgtctg     3720

ggagagagga taggatggga atgctgccct aaaggaaggg ctggtgaaag gtgtttatac     3780

aaggttctat taaccacttc taagggtaca cctccctcca aactactgca ttttctatgg     3840

attaaaaaaa aaaaaaaaaa gtagatttta aaaagccaca ttggagctcc cttctaccca     3900

ctaaaaaata accaattttt acattttttg agggggagtg agttttagga aaggggaatt     3960

aagattccag ggagagctct ggggatagaa cagggcgcag attccatctc tccccaagcc     4020

cctttttagt gactaagtca aggccccaac tcccctcccc caccctacgc tgagcttatt     4080

cgagttcatt cgtactaata atccctcctg cggcttcctc attgttgctg ttttaggcca     4140

ccccagctca gccaatgatt cctttccctc tgaatgtcag ttttgttttt aaaagtcact     4200

tgcttagttg atgtcagcgt atgtgtattt ggtggggaaa acctaatttc ggggatttct     4260

gtggtaggta ataggagaag aaagggcact gggggctgtt ctccttcctt ccctgggctg     4320

tatccatgga ctcctggaag gcacagagaa gggagctata agaggatgtg aagttttaaa     4380

acctgaaatt gttttttaaa gcacttaagc acctccatat tatgacttgg tgggtcaccc     4440

cttagcttcc tccctctccc accaagacta tgagaacttc agctgatagc tgggggctcc     4500

ccagatgagg atgcagggat ttgggagcag tggaagaggg tgcccaacct tgggttggac     4560

caacccttgg ctcgcagctc aactctgctt cccgcattcc tgctccacgt gtcccagctt     4620

ctcccctgtg acgggaaggc aggtgtgact ccaggctctg cactggttct tcttggttcc     4680

tcccaccagg ccctttgttc ctcatgtccc catgtttctc tccctctgcg tcttagcacc     4740

tttcttctgt tcaaagtttt ctgtaaattt tctctttttt tctttctttc tttttttttt     4800

ttttataaat taatttgctt tcagttccat cttgtgggtg cattctgtgt tcttacctgt     4860

ggctgtcagg cagggggatt gtgatgggag cagctttcct ggagtccttc acagcggcgt     4920

ttacctgggc cgaaagacac tctgcaagcc acacggccta cagacactgc gcctccccac     4980

aaaacacgaa cggcagcaca actgtcgaga ctatgtgctg gtataggagc agaggctctc     5040

acctgcccta aaagctgttt aagacttgga aggacattcc cacaacatgg aattttgtat     5100

ctctgtccct tcagaagtag tggtttcact ccttccctta ttagagagga ggcaagcccc     5160

ttacctactt ttgttataat tggcccttca ccctgctgag gtgacggaca ggcttaggca     5220

gtgctaataa tggcctggct ttagctccaa taaacactcc acaggcttcc ccacaaaagg     5280

ccttattggg agcttgggag ggcgggggcc agatttaagg agctggaagg gtagga         5336


<210>  1069
<211>  13760
<212>  DNA
<213>  homo sapiens

<400>  1069
ccgcggcgcc gggacagccc cgggactctg ccaggtggat gttgtgcgta gccggagcca       60

ggttgaagag agaactcgat gccaccgcaa cggtattggc gaaccggcag gatgaaagtg      120

agcagtccag aaagcggctt atcgaacaga gccgggagtt caagaagaac actccagagg      180

atttgcgcaa gcaggtagcg ccgctgctga agagtttcca aggagagatt gatgcactga      240

gtaaaagaag caaggaagct gaagcagctt tcttgaatgt ctacaaaaga ttgattgacg      300

tcccagatcc cgtaccagct ttggatctcg gacagcaact ccagctcaaa gtgcagcgcc      360

tgcacgatat tgaaacagag aaccagaaac ttagggaaac tctggaagaa tacaacaagg      420

aatttgctga agtgaaaaat caagaggtta cgataaaagc acttaaagag aaaatccgag      480

aatatgaaca gacactgaag aaccaagccg aaaccatagc tcttgagaag gaacagaagt      540

tacagaatga ctttgcagaa aaggagagaa agctgcagga gacacagatg tccaccacct      600

caaagctgga ggaagctgag cataaggttc agagcctaca aacagccctg gaaaaaactc      660

gaacagaatt atttgacctg aaaaccaaat acgatgaaga aactactgca aaggccgacg      720

agattgaaat gatcatgacg gaccttgaaa gggcaaacca gagggcagag gtggctcaga      780

gagaggcgga gaccttaagg gaacagctct catcggccaa tcactccctc cagctggcct      840

cacagatcca gaaggcacca gacgtggagc aggccataga ggtgctgacc cgctccagcc      900

tagaagttga gttggccgcc aaggagcggg agatcgcaca gctggtggag gacgtgcaga      960

gactccaggc cagcctcacc aagctgcggg agaattcggc cagccagatc tcacagcttg     1020

agcagcagct gagcgccaaa aacagcacac tcaaacaact ggaagaaaaa ctcaaaggcc     1080

aggctgacta tgaagaggtg aagaaagagc tgaacattct gaagtccatg gagtttgcac     1140

cgtccgaggg cgctgggaca caggatgcgg ccaagcccct ggaggtgctg ttgctggaga     1200

agaaccgctc gctgcagtcc gagaacgccg cgctgcgcat ctccaacagc gacctgagcg     1260

ggtcagccag gaggaaaggg aaagaccagc ctgaaagtcg gcgcccggga tctttgccgg     1320

ccccccctcc ttctcagttg ccccgcaacc cgggggagca ggcttccaat actaatggta     1380

cacaccagtt ctcaccagcg gggttaagtc aagacttttt cagctcatcc ctggcaagcc     1440

ccagcctacc cctggcttct acaggaaaat ttgcactaaa ctctcttctc cagcggcagc     1500

taatgcagtc cttctactcc aaggctatgc aggaagccgg aagcacaagc atgatttttt     1560

caacaggtcc atacagcaca aactccatat cttcccaaag tccattacaa caaagcccag     1620

atgtcaatgg catggcccca tcccccagcc agtcagaaag tgctgggagc gtctccgagg     1680

gcgaggagat ggacactgca gaaatcgccc ggcaggtcaa agagcagctg attaagcaca     1740

atatcggaca acgtattttc ggacattatg tgttgggact gtctcaaggg tccgtgagcg     1800

agattctggc ccggcccaag ccatggaata aactgactgt tcgtggcaag gagccatttc     1860

acaagatgaa acagttcctc tccgatgagc agaacatcct ggccctccgt agcatccaag     1920

gcagacaaag agagaatcca ggccagagcc tgaacagact atttcaggaa gtaccgaaac     1980

gaagaaatgg gtctgaaggt aacatcacca cccggatccg agcctcggag actggctctg     2040

atgaagccat caagtccatc ctagagcaag ccaagaggga gctccaagtg cagaaaactg     2100

cagagccggc ccagccttcc tccgcatccg gcagcgggaa ctctgatgac gccatccgct     2160

ccatcctgca gcaagcccgc cgggagatgg aggcccagca ggctgccctc gaccctgcct     2220

taaagcaggc accactgtcc cagagtgaca tcaccatcct cacccccaag cttctgtcca     2280

cctcgcccat gcccaccgtg tccagctacc cacctctcgc catctccctg aagaagccct     2340

ccgcagctcc tgaggccggt gcctctgctc tgccgaaccc cccggccctc aaaaaggagg     2400

cccaggacgc ccccgggctg gacccccagg gagcagccga ttgtgcacaa ggggtcctga     2460

gacaggtgaa aaatgaggtg ggccgcagcg gtgcctggaa ggaccactgg tggagcgcgg     2520

tgcagccgga gagaagaaat gccgcctcct ccgaggaggc caaggccgaa gaaacgggcg     2580

gcgggaaaga gaagggcagc ggtggcagcg gaggtggcag ccagcctcgg gccgagcgca     2640

gtcagctcca gggaccctcg tcgtcagagt actggaagga gtggcccagc gctgagtccc     2700

catactccca gagctcagag ctgagtctga ccggggccag ccgcagcgag acaccacaga     2760

acagccccct gccatcctcc ccgatcgtgc ccatgtccaa gcccaccaag ccctcggtcc     2820

ccccgctgac ccccgagcag tacgaggtct acatgtacca ggaggtggac accatcgagc     2880

tcacccggca ggttaaggaa aagctggcca agaacggcat ctgccagaga atcttcgggg     2940

agaaggtgct gggcctgtcc cagggcagcg tcagcgacat gctgtcccga ccgaagccat     3000

ggagcaagct gacgcagaaa ggccgagaac ccttcatccg gatgcagctc tggctgaacg     3060

gcgagctagg ccagggtgtt ctacccgtcc agggccagca gcaagggcca gtcctccact     3120

ccgtgacatc gctccaggac ccgctgcagc agggctgtgt gagctcagaa agcactccaa     3180

agacctccgc cagctgcagc cctgcccctg agtccccgat gagttccagt gagtcggtga     3240

agagcctgac cgagctggtc cagcagccct gtccccccat cgaggcgagc aaggacagca     3300

agccaccaga gcccagtgac ccgccagcat ccgactccca gcccacaacc ccgctgcctc     3360

tctccggaca ctcggccctc agcatccaag aattagtagc catgtccccg gagctggaca     3420

cctacggcat aaccaagcgg gtgaaggagg tgctgacgga caacaacctc ggccagcgct     3480

tatttgggga gaccatctta gggctcaccc aaggctctgt ctctgacctc cttgcccgcc     3540

ccaaaccctg gcataagctc agtctgaaag gacgagagcc cttcgtccgg atgcagctgt     3600

ggctgaacga ccccaacaat gtggagaagc tgatggacat gaaacggatg gagaagaaag     3660

cctacatgaa gcggcggcac agctcagtca gtgacagcca gccctgcgaa ccgccctctg     3720

tcggcaccga gtacagccag ggcgccagcc cccagcccca gcaccagctg aagaaacccc     3780

gggtggtgct ggctccggag gagaaggagg cgctgaaacg agcgtatcag caaaagccat     3840

acccgtcacc aaaaaccatc gaagacctcg ccacccagct caacctgaaa accagcaccg     3900

tcatcaactg gttccacaac tacaggtctc ggatccgcag agaactgttc attgaggaaa     3960

ttcaggccgg gagtcagggc caggcgggcg ccagcgactc accctcggcc cgcagcggcc     4020

gggcggcgcc cagctcggag ggcgacagct gcgacggcgt ggaggccact gagggcccag     4080

gcagcgccga caccgaggag cccaagtctc agggagaggc cgagcgggag gaggtgccgc     4140

ggccggcgga gcagacggag ccgccgccct cggggacccc gggcccggac gacgcccgcg     4200

acgacgacca cgagggaggc cccgtggaag gcccggggcc cctgcccagc cccgcctccg     4260

cgaccgccac cgccgcgccc gcggcccccg aggacgccgc tacctcagcc gccgccgcgc     4320

cgggggaggg ccccgcggcc ccgagctccg cgccgccgcc cagcaacagc agcagcagca     4380

gcgccccccg caggcccagc tcgctgcaga gccttttcgg cctccccgag gccgcgggcg     4440

cccgggactc gcgcgacaac cccctgcgca agaagaaggc cgcgaacttg aacagcatca     4500

tccaccgcct ggagaaggcc gccagccggg aggaacctat cgaatgggag ttctgagggg     4560

ccgcggccct ggggcgggca gccaggctgg gccgcaaggg cctggacggg gtcggacggg     4620

gcaggcgctg cggacaccgt ggcctgggct tggcccgcgg cctgcaccga ccccgggccg     4680

gacctgagcc cgcagcccag accccctcca cggtccgcgg cctgcaccga cccgaggccc     4740

agatccaagg ccgcggccca gacccactct gcggcccggg ccgaccctgc ggcctccacc     4800

aaccccgcgg cccagaccca gcccgcggcc tggacccctg gaccgctttg cgcacttacc     4860

gccctgcggg ccacagggca aaatcgccat aggccaaggt gcatatagaa aacaaaggag     4920

cattaagccc aatctatgtc gtgttttcaa ggaagaaaac ggaaatgtgt ggtcgagctt     4980

ttttgtaccc tgaagtgttt tttttattgc cctaagtgat ttccacaggt tctggaataa     5040

ctcttacagc tttgccttgt gtcctcctgt tccgtgtggg ctttaaaaga aaaaaaatca     5100

aacccacata ttaaaagggg gctttttatc tgccatctaa tggcttcaga gcgataatac     5160

actattatct tcttaaacca ggaaaaaata aaaggggggg tgggattttt cagaaaaatt     5220

aaaaaagaaa gtttttgtag ctgttcagtt gccactaaga gattgcacag tcaaaacgac     5280

tctaaacaca ctagtttgga ttcctaaata ttttcaagaa aagaatcttc tcgtttgaaa     5340

ctttgaatta aaataaaaca catttactcc acatattttt taacaaaaag aaaacgtcac     5400

atcaggaaac tctgattttg tggtagctga catagtgttt tcttgtacgt gaatagaatc     5460

ctgacatgta gtgcacattg atgtatagct ttaactgacc ctgggttttg cagaccaggg     5520

tttgtttaat acactccatt ctaggccaaa tcaggacaaa aaaaagaaaa aaaaagaaaa     5580

aaaaaaaaga aaagatccga atctaggtat tttataatct gctttttaac ctctaaccgc     5640

agagcacgct gatcagacct catatcttgg aggtttagga gacaagttag aactgtagca     5700

tgtacctgtt aattttgttt aatttatggt gtctcaatct gtctgtgcgt ctgcacgtgt     5760

gcaagcattg aaagaaagga gagagtagtc cgggcgagca cagcaggcag ttccagggcc     5820

agacgggccc atccccaagt agatagcagt ctacggatct ctctctggca cagaaggcac     5880

ctcacctcac accactctcc tggatacctg atgaactgag ccctcccagg ggaagacact     5940

ccccaggcct gggcagggct tacacgcgca ctctctctct tctttccctt tttcttccca     6000

ccgcaagcac tgatgaccct gttgaactcg tgggaaactt cctttctctg caggagagag     6060

aacgtggcat tctgggctcc ccactcccat ccctgtagaa atggcccaaa ctcacaccaa     6120

aacgtggatg ctcttcaact tccaaaccta ccatttgccc ttctttcatt tcgcctctta     6180

gttcttttta tgcacagttt tagggcagtc taagtacaaa ctgaaagtct aacttgtctc     6240

tgattcctcc cttgtctatg tgtatatgcg tgagaataga ggcgggtgag agtgtgcgtg     6300

cgtgtgcgtg tgtgcaattt tatacgtctg tgtattttct taagtacctg tgcacacgta     6360

gagtgcatta ctgccacctt tttcaataag ctgttttatc agttacggct tctacaagtt     6420

tgctaattta gacttcttta ttgccatatc tttaaactaa caatagatga tttcggtata     6480

tatatatatt tttttttgct tatttatagg tgctgtattt tattatctga ttgttaggaa     6540

gggatgaaag gggcaaatat tctttagagg gatagactgc cggcagtatt gggtataatt     6600

tacaagatgt agttgtcata ctgtatatta ctgattgaaa actttttgac cgtattgtgt     6660

atcattgaaa cctttgtctt aggtcaacat ctttggatga cattttaatg gtgcattcat     6720

tatttcttaa gtttaattaa tattactttt ttttttattt ggggggtggg agggagttat     6780

aattttaaag gtatgctctg gctgttccac ctccgtgtgc ttgttaatta acttgtagga     6840

ctttgactgt aagatgtgaa accacgtttc ttgcatgatg ttttagagat tatttcattt     6900

acagtctttt aacctgcagc tgcagcactt agttcacgtt ttcacaaatt tcaagagtca     6960

ctacactaaa gacaatgcct tttcatgaat aagaagtttt cagaaggctc tagggggctg     7020

ggaggcaggc tgttcgtttg tcttttgttg ggggtatcat ttctgaactt gaaatccagt     7080

tcagggagaa gagaattcaa aattagagga gcttaagggg acacgggtca acatctagct     7140

cgattcaggt gcattgagaa gagtgagttc acatcggtga cccttaggac agtgagtggc     7200

agagccctga cgactgtggt gtcctctcca caaaaccctc aagggacttt tgtcatcatg     7260

tgtgatgaat ctttaaatat cgtctaattt tcataagaat gaaaagaagt taacaggaaa     7320

tagtaggcta gggtttagtt ttaaaggcat gactgttatt tacaaaggtg ttaaatctga     7380

ggaaattgac aaatacagat ttgtccattc tagtggccaa acagtaacag tctaaaatgc     7440

agtcattttg accctcccaa gcaatttagt catatgtgtt gttttctctt ttctgttttt     7500

acttcttaga tttttaacta ggttactgtt ggttcccatt ctgtcttttt tgccagactt     7560

acatctggtg ccagatacaa tcagttggtt aaattttgct tgcagttctg tgtatttttt     7620

ttcctctatt atttattttt ttaaaaaaaa tagagatcct aaccttagat ctttgatgtg     7680

aagctagcac tgtctgtaat acttctaaga gctgccacta aaataataca gcaatccgtg     7740

gccaggggag caccccctcc tggttgggcc cctcagttgg agtctaaggg ttaatctctc     7800

atcttgctaa gcagtattca agtgccttga acagtgtccc ctcggcatgg ctccccttca     7860

gcaggctggc attccaagca gtggcccccg caggcagccg acccccttcc tcttcacgct     7920

ctatgagttt aaaaagctga tttgtacctc tcccctgggg gaaacggttc catataaaac     7980

actaacactt aattacaagc tccattatgc cattttaaat ggcttctttt tgttaattgg     8040

aggcattgtt cataacttaa ggcttttgcc attaacttag ctggctaagc agaggctcgg     8100

ggtaaaatca gtgtttgcat ttagcctctt gacccggagt tccggcccaa gctcccttgt     8160

gatagccgag atggcaggtg tgtgagttct gtcctagacc tgtgcccaac tcacttccac     8220

cccagaggag tcttctgtcc tcctccccaa cccccgagct ccctggtaac ctcctcttga     8280

acttctgtat cagtgaagac atctgtggtt tctgctcacc agacctctct ttagaaaggg     8340

ttatcagagc catggagctt agctcaattg gattcttcta gacgatctta ggaggcatct     8400

tggcatgagg cagcttctaa gcgtctcctg ggacaggatt ggggtgacag cccagggatg     8460

catgcatggg agaactctct gagaaatgcc aggatcgtgg ctcacaggga cccaccatca     8520

aaacctgcta ctttgtgcaa gtaattgagg caaaagatac cagtcgacag cctccctggg     8580

gtagatccct tgtacctcca aagtacaaat acctccctgc tcagtttcct tcctgtcgcc     8640

atctttgttt tcttcccatt gaaaaaccat cctgtctgat gtggacgttc aggtctgctg     8700

gttggcggtc cgggcccaga gtgcagcaga gctctgggtt aaatattcct ttctggccac     8760

cgcccaagcc caggtggcca gctctcatac cccatctccc tccttggcca gggccagcat     8820

caggcgtgca gctcatgacc agtttacaca ggctgcaaag agatcgctgt gggcctcggc     8880

tgactacttt aagattatgc cacagccagg ccctaaaaag agaggggaac aggagtcccc     8940

aggtgagctc tctgacgggc aggtgccttc ccgactaagg ttggactgga tgactttgtt     9000

cctcctgcat gcatgtcctt tgatgcaagg gtgatcaatg aactctgttg acattctatg     9060

caatgttttt cattcctctg attttagcaa agcaaatctt actgaaaaat agcagagcca     9120

ggggaacaga cgcatgtcct tctgggagtc acacaaaagc agagagattt tgaactgagg     9180

ggcgacagcc tttgccttaa atgcagtatg acaggcgctt cttggcagac cagtaaaaac     9240

aaaagcccat agaccttact catcccaagg ccgacaagcc agctgtacag ggcgagatgt     9300

agcaacacgg ggcatgagcg gtgggcgtgc tgggctattt gctgtggtac tttaggctgg     9360

aggtttggct cctgtgctgc cggtgggggg ccctgtccct ccccagatgt cctccctctt     9420

cttcacactc ctcattgtcc cttctacctc actaacctgt cttctccatc tgatgtcacc     9480

cagaaccaca ccccacagaa ctgtgaggca cgtgggctgg agagagcaga aaagctgcca     9540

gcgcagcaga cacgaacatc cctctgcctg gtgggccggc tttgtgtgtc tctccttttg     9600

tgagcgcaac acggacaaac agctgtgctc tgcaaggcac acggatgttt cccttccacc     9660

tgttcccaaa gctccagcag ctgtttcttt tgcaggcagg gcgtggtctc ggggctccga     9720

gggtcttgtc tttggtccgc cttcctttct gtccagtcct gctcagctgt taagatccat     9780

catggccatt atccttgtcc cggactgccc caaagttccc agctggcttt ggggaacact     9840

gtagctcttg ggtgtctctt gtctctggca tggttttagc gtcactgcga acactccttt     9900

gcaaacatca aacatctcaa agacggaaaa ggatagatgg cttcctccag cctacacgcc     9960

ccgtccacag tggcatcacc ctcttatccc aaaagaatat gccagttccc atccagcacc    10020

gaagaaaatc agctcctggg gctggtggtt ggaggtgggt ctgtccactg tgggggccaa    10080

agtgttcccc tgctggagac agtttgcaag taagaaccta aggatgggga cagcatcctg    10140

tgcttgggca ttgaccagcc aaagctcaca tttagaaagc cctcagtgct tctgtggttt    10200

cacctgggca tcgacgacat tagggaagcc tttgtgacca caagggcagg gcttgtgccc    10260

tgagtggcga ggtggtgacc tgaggccagt gtgatgtggt tggatctcag cgtgtactga    10320

atgccagtct ggccggcaca ctcgaacgct aagagaatgg tccaatttga tgatcttatt    10380

tctatttcga tcaggttttg actttttgta gatgaaaact accagggaaa aggggaagca    10440

ggtacccaat aaagtttaga aagatccagt ctgtgaaacc cttagagatg ggctgaaagt    10500

taagtccacc aacccttggg cttaatcagg acggaagagg agggggtgtg gggggcagag    10560

cgtaaaacaa gccccagccc tactcccggc cccccagccc agtcttccca atcccagagg    10620

ccccggcggc ctgtgctcct caccaccctg gtcaggggaa tagaaggaaa tgcaatttcc    10680

gcctgtctgc ccgacttcca aaaactgcct cctcctgccc aggcctctcc caccaccacc    10740

ttccctccaa agataaccgt gtccatgcca tccgtggcat catctcgagt tttcattttt    10800

ggatgaagtg acatttagct ttaacaagac atttccaaag cgcctagtct cctccaaaat    10860

gctaacttta aaagttgggc attgtaggcg aaaaatccca aaaaaaaaaa aagacaaaaa    10920

aaaaaggctg gcgagagaaa gacatttggc tatgcataaa tgtgcacttc ccccatgccc    10980

ccgttcttaa actcttaaga tgcctttgag ttgcttttca tgaatccttt tagtttaccc    11040

gataatgtta agaaagcatt agtctacgtt actgtaattt ctgtagtgtt tacgctttaa    11100

tttctaccac aaaatatgct atatgctatg tatcaagctt tctgtaatca gaaagaaaag    11160

gtgccttata tcccaatgtc acggctacat ccctatggaa attaatcaga agcacagtgt    11220

gtacggaagc attgggactt ctgctggtga aacaagagac cattcagcaa gacacattga    11280

agtggcacgg agctgctttt gttttataat tcttttttcc ccccttttcc ttcttctttt    11340

ttattatttt attatttttt ttgtactttg ctttaaacgg aaagcactta aatagatgac    11400

tatgtgtaaa agctctgtgc aattgaaatc atttttcttc attttaaaaa aataacgtat    11460

tgcacaccaa atgaactcaa agtaagcttt agaccaggac gattcaggtt atgaatgagt    11520

ttgttcactg tagttccgtt tgttcatgaa ccgaagggaa aacaggcctc cccgactccc    11580

tccagtctcc cagcctgcct cttggtgacc actgtgctgg gcgtgcaggg cccgcgggct    11640

ctggccggag ccgctggcct gacgaggcag gatagggagt atccgtgatt cagaagctga    11700

gacccttccc cagtgtctga ggccacagcc atcccttcca gcacttaatc ttgtcttgtt    11760

gaaatggact gactgctact gacctgccgg cgtgcgtgag ggtgattata aaaggatgtt    11820

tccttgagaa aaaaaaaatt atttctatcc tcttctattt attattaggt taatcattta    11880

agtacttatc aggagtgtat tgttattttg tgttttgttg tcataaatgc tttttgctgt    11940

cactctagtg gttactatcc tctgccttcc tctcctcccc tactccccca gagaaccaag    12000

gcgtctgggg gattgactgg ggggcagagg gggtttcccc agcaaaatca aacacctgtc    12060

tccagagtag ccactcaaaa actggtggtc tctatgtgtc taacttttta aatgagagtg    12120

tttatgaaca aaaaaattta ccaacgtgtg agggagttgc tgagttgaag aatgctcgct    12180

tgaggagctt cagaggaatc ttagcaaagc caagttcagt tccccaaagc ctcctagagc    12240

ctctggtaag acttctgggt tcatgaagtt tcggcgagcc gtggtcagag agggcgcggt    12300

ggcctggcca agactttacc tccaagcgag agagtgattt cttgcaaggc ccgcatgggt    12360

tgatacgttt tggttggttt tttgttgttg tttttcttgc gtacaaagtt ggtcaaaacc    12420

atctttcaaa gcaacagtgt tttgtagtac caggctgtgg cttgagggct cacctaggag    12480

atcataggca gagggcccct ttcccctata ggtggttcaa cgtggaggaa ggttgggtgt    12540

ggagattgct tgctgtggcc ccaagctcag ccagcaggac acccagttgt tgccaatcag    12600

gtgtgaaggt gaggcgccct gccttgatcc catgggccca gcagaaggaa acttacccca    12660

ggccaaggca agggccctgc tcaccccaag gtaggctggg aagagcatct ctttccatat    12720

catcacctcc ccttctccaa gattgccggg ggccctgatt ttgttctctc tttgaaagaa    12780

accctccacc gaaacaatgg tccccatctc cccagaagcc tttttttttt tcatttttct    12840

ctaattagtc tatgcatttc tctctctcaa accatcttct gcctcttccc ttgagaaaac    12900

gggcatctca cgtaccccca tctgagacct cttggaaaaa aaaaatcccg tgtattctgg    12960

agatgtgaga attcacccaa aattcttaaa acattggaga atagcttgtt ataaaataaa    13020

agtgggggta aaaagaaggt ggttttcccc acatcccttt gcattgaata agagacctag    13080

ttctttgcgt ttgtgcaata actctttgct gcttgccttg agagcgggta gcaccacgct    13140

cctgtccaga ctactaacag cacaagacgc actcacaggg tggcggaatc ttccggaaaa    13200

ctctctataa gctcagctcc ccccacccca cccccactct agcgttttgt cacgtcttac    13260

attttagcag tattttatat tttctgtaac gcaccaagtc ttagatcttt ctagagcttg    13320

tttgttcatc ctcacaatca cagatttttt tctccaatcc tcacagagac ccaattgacc    13380

aaaaaagaaa aaaggaaaaa aaaaaagtcg tctttttttt ttttttttgt acaaatcgct    13440

ttgagatgcc tctggtgtgt tgctgtgtga catctctctg gtaacatttt atttcttgct    13500

atttgttttt ctacattaag agtcaaagtt gacctggctg gcgtgggggt gggggaggca    13560

cccgtcggcc ccttggtgtt gtccctctgt ctttggttag ccatacgatg tttgttctca    13620

gcactgtaca acggtcccta tataatacgg agaagcaata tcactgtatg agactcacac    13680

catgtattat tattcactag caccctaggt gtgataattg aagtaaatat cttttataca    13740

aacacaaaaa aaaaaaaaaa                                                13760


<210>  1070
<211>  4871
<212>  DNA
<213>  homo sapiens

<400>  1070
agtccctgcc ctcccctggg gagggtgagt cacgccaaac tgggcggaga gtccgctggc       60

ctcactccta gctcatctgg gcggcggcgg caagtgggga cagggcgggt ggcgcatcac      120

cggcgcggag gcaggaggag cagtctcatt gttccgggag ccgtcaccac agtaggtccc      180

tcggctcagt cggcccagcc cctctcagtc ctccccaacc cccacaaccg cccgcggctc      240

tgagacgcgg ccccggcggc ggcggcagca gctgcagcat catctccacc ctccagccat      300

ggaagacctg gaccagtctc ctctggtctc gtcctcggac agcccacccc ggccgcagcc      360

cgcgttcaag taccagttcg tgagggagcc cgaggacgag gaggaagaag aggaggagga      420

agaggaggac gaggacgaag acctggagga gctggaggtg ctggagagga agcccgccgc      480

cgggctgtcc gcggccccag tgcccaccgc ccctgccgcc ggcgcgcccc tgatggactt      540

cggaaatgac ttcgtgccgc cggcgccccg gggacccctg ccggccgctc cccccgtcgc      600

cccggagcgg cagccgtctt gggacccgag cccggtgtcg tcgaccgtgc ccgcgccatc      660

cccgctgtct gctgccgcag tctcgccctc caagctccct gaggacgacg agcctccggc      720

ccggcctccc cctcctcccc cggccagcgt gagcccccag gcagagcccg tgtggacccc      780

gccagccccg gctcccgccg cgcccccctc caccccggcc gcgcccaagc gcaggggctc      840

ctcgggctca gtggatgaga ccctttttgc tcttcctgct gcatctgagc ctgtgatacg      900

ctcctctgca gaaaatatgg acttgaagga gcagccaggt aacactattt cggctggtca      960

agaggatttc ccatctgtcc tgcttgaaac tgctgcttct cttccttctc tgtctcctct     1020

ctcagccgct tctttcaaag aacatgaata ccttggtaat ttgtcaacag tattacccac     1080

tgaaggaaca cttcaagaaa atgtcagtga agcttctaaa gaggtctcag agaaggcaaa     1140

aactctactc atagatagag atttaacaga gttttcagaa ttagaatact cagaaatggg     1200

atcatcgttc agtgtctctc caaaagcaga atctgccgta atagtagcaa atcctaggga     1260

agaaataatc gtgaaaaata aagatgaaga agagaagtta gttagtaata acatccttca     1320

taatcaacaa gagttaccta cagctcttac taaattggtt aaagaggatg aagttgtgtc     1380

ttcagaaaaa gcaaaagaca gttttaatga aaagagagtt gcagtggaag ctcctatgag     1440

ggaggaatat gcagacttca aaccatttga gcgagtatgg gaagtgaaag atagtaagga     1500

agatagtgat atgttggctg ctggaggtaa aatcgagagc aacttggaaa gtaaagtgga     1560

taaaaaatgt tttgcagata gccttgagca aactaatcac gaaaaagata gtgagagtag     1620

taatgatgat acttctttcc ccagtacgcc agaaggtata aaggatcgtt caggagcata     1680

tatcacatgt gctcccttta acccagcagc aactgagagc attgcaacaa acatttttcc     1740

tttgttagga gatcctactt cagaaaataa gaccgatgaa aaaaaaatag aagaaaagaa     1800

ggcccaaata gtaacagaga agaatactag caccaaaaca tcaaaccctt ttcttgtagc     1860

agcacaggat tctgagacag attatgtcac aacagataat ttaacaaagg tgactgagga     1920

agtcgtggca aacatgcctg aaggcctgac tccagattta gtacaggaag catgtgaaag     1980

tgaattgaat gaagttactg gtacaaagat tgcttatgaa acaaaaatgg acttggttca     2040

aacatcagaa gttatgcaag agtcactcta tcctgcagca cagctttgcc catcatttga     2100

agagtcagaa gctactcctt caccagtttt gcctgacatt gttatggaag caccattgaa     2160

ttctgcagtt cctagtgctg gtgcttccgt gatacagccc agctcatcac cattagaagc     2220

ttcttcagtt aattatgaaa gcataaaaca tgagcctgaa aaccccccac catatgaaga     2280

ggccatgagt gtatcactaa aaaaagtatc aggaataaag gaagaaatta aagagcctga     2340

aaatattaat gcagctcttc aagaaacaga agctccttat atatctattg catgtgattt     2400

aattaaagaa acaaagcttt ctgctgaacc agctccggat ttctctgatt attcagaaat     2460

ggcaaaagtt gaacagccag tgcctgatca ttctgagcta gttgaagatt cctcacctga     2520

ttctgaacca gttgacttat ttagtgatga ttcaatacct gacgttccac aaaaacaaga     2580

tgaaactgtg atgcttgtga aagaaagtct cactgagact tcatttgagt caatgataga     2640

atatgaaaat aaggaaaaac tcagtgcttt gccacctgag ggaggaaagc catatttgga     2700

atcttttaag ctcagtttag ataacacaaa agataccctg ttacctgatg aagtttcaac     2760

attgagcaaa aaggagaaaa ttcctttgca gatggaggag ctcagtactg cagtttattc     2820

aaatgatgac ttatttattt ctaaggaagc acagataaga gaaactgaaa cgttttcaga     2880

ttcatctcca attgaaatta tagatgagtt ccctacattg atcagttcta aaactgattc     2940

attttctaaa ttagccaggg aatatactga cctagaagta tcccacaaaa gtgaaattgc     3000

taatgccccg gatggagctg ggtcattgcc ttgcacagaa ttgccccatg acctttcttt     3060

gaagaacata caacccaaag ttgaagagaa aatcagtttc tcagatgact tttctaaaaa     3120

tgggtctgct acatcaaagg tgctcttatt gcctccagat gtttctgctt tggccactca     3180

agcagagata gagagcatag ttaaacccaa agttcttgtg aaagaagctg agaaaaaact     3240

tccttccgat acagaaaaag aggacagatc accatctgct atattttcag cagagctgag     3300

taaaacttca gttgttgacc tcctgtactg gagagacatt aagaagactg gagtggtgtt     3360

tggtgccagc ctattcctgc tgctttcatt gacagtattc agcattgtga gcgtaacagc     3420

ctacattgcc ttggccctgc tctctgtgac catcagcttt aggatataca agggtgtgat     3480

ccaagctatc cagaaatcag atgaaggcca cccattcagg gcatatctgg aatctgaagt     3540

tgctatatct gaggagttgg ttcagaagta cagtaattct gctcttggtc atgtgaactg     3600

cacgataaag gaactcaggc gcctcttctt agttgatgat ttagttgatt ctctgaagtt     3660

tgcagtgttg atgtgggtat ttacctatgt tggtgccttg tttaatggtc tgacactact     3720

gattttggct ctcatttcac tcttcagtgt tcctgttatt tatgaacggc atcaggcaca     3780

gatagatcat tatctaggac ttgcaaataa gaatgttaaa gatgctatgg ctaaaatcca     3840

agcaaaaatc cctggattga agcgcaaagc tgaatgaaaa cgcccaaaat aattagtagg     3900

agttcatctt taaaggggat attcatttga ttatacgggg gagggtcagg gaagaacgaa     3960

ccttgacgtt gcagtgcagt ttcacagatc gttgttagat ctttattttt agccatgcac     4020

tgttgtgagg aaaaattacc tgtcttgact gccatgtgtt catcatctta agtattgtaa     4080

gctgctatgt atggatttaa accgtaatca tatctttttc ctatctatct gaggcactgg     4140

tggaataaaa aacctgtata ttttactttg ttgcagatag tcttgccgca tcttggcaag     4200

ttgcagagat ggtggagcta gaaaaaaaaa aaaaaaagcc cttttcagtt tgtgcactgt     4260

gtatggtccg tgtagattga tgcagatttt ctgaaatgaa atgtttgttt agacgagatc     4320

ataccggtaa agcaggaatg acaaagcttg cttttctggt atgttctagg tgtattgtga     4380

cttttactgt tatattaatt gccaatataa gtaaatatag attatatatg tatagtgttt     4440

cacaaagctt agacctttac cttccagcca ccccacagtg cttgatattt cagagtcagt     4500

cattggttat acatgtgtag ttccaaagca cataagctag aagaagaaat atttctagga     4560

gcactaccat ctgttttcaa catgaaatgc cacacacata gaactccaac atcaatttca     4620

ttgcacagac tgactgtagt taattttgtc acagaatcta tggactgaat ctaatgcttc     4680

caaaaatgtt gtttgtttgc aaatatcaaa cattgttatg caagaaatta ttaattacaa     4740

aatgaagatt tataccattg tggtttaagc tgtactgaac taaatctgtg gaatgcattg     4800

tgaactgtaa aagcaaagta tcaataaagc ttatagactt aaaaaaaaaa aaaaaaaaaa     4860

aaaaaaaaaa a                                                          4871


<210>  1071
<211>  6618
<212>  DNA
<213>  homo sapiens

<400>  1071
attagaaaca aattttggtc ggtgctccct gggctgctgg tcttctttac cttccagctg       60

ctcacagaac agagagtttc tacatacaag cagaagatgt gaaaatattg ggaataaata      120

aagtatatgc ttataaacaa gttgtggctg ctcctggtta cgttgtgcct gaccgaggaa      180

ctggcagcag cgggagagaa gtcttatgga aagccatgtg ggggccagga ctgcagtggg      240

agctgtcagt gttttcctga gaaaggagcg agaggacgac ctggaccaat tggaattcaa      300

ggcccaacag gtcctcaagg attcactggc tctactggtt tatcgggatt gaaaggagaa      360

aggggtttcc caggccttct gggaccttat ggaccaaaag gagataaggg tcccatggga      420

gttcctggct ttcttggcat caatgggatt ccgggccacc ctggacaacc aggccccaga      480

ggcccacctg gtctggatgg ctgtaatgga actcaaggag ctgttggatt tccaggccct      540

gatggctatc ctgggcttct cggaccaccc gggcttcctg gtcagaaagg atcaaaaggt      600

gaccctgtcc ttgctccagg tagtttcaaa ggaatgaagg gggatcctgg gctgcctgga      660

ctggatggaa tcactggccc acaaggagca cccggatttc ctggagctgt aggacctgca      720

ggaccaccag gattacaagg tcctccaggg cctcctggtc ctcttggtcc tgatgggaat      780

atggggctag gttttcaagg agagaaagga gtcaaggggg atgttggcct ccctggccca      840

gcaggacctc caccatctac tggagagctg gaattcatgg gattccccaa agggaagaaa      900

ggatccaagg gtgaaccagg gcctaagggt tttccaggca taagtggccc tccaggcttc      960

ccgggccttg gaactactgg agaaaaggga gaaaagggag aaaagggaat ccctggtttg     1020

ccaggaccta ggggtcccat gggttcagaa ggagtccaag gccctccagg gcaacagggc     1080

aagaaaggga ccctgggatt tcctgggctt aatggattcc aaggaattga gggtcaaaag     1140

ggtgacattg gcctgccagg cccagatgtt ttcatcgata tagatggtgc tgtgatctca     1200

ggtaatcctg gagatcctgg tgtacctggc ctcccaggcc ttaaaggaga tgaaggcatc     1260

caaggcctac gtggcccttc tggtgtccct ggattgccag cattatcagg tgtcccagga     1320

gccctagggc ctcagggatt tccagggctg aagggggacc aaggaaaccc aggccgtacc     1380

acaattggag cagctggcct ccctggcaga gatggtttgc caggcccacc aggtccacca     1440

ggcccaccta gtccagaatt tgagactgaa actctacaca acaaagagtc agggttccct     1500

ggtctccgag gagaacaagg tccaaaagga aacctaggcc tcaaaggaat aaaaggagac     1560

tcaggtttct gtgcttgtga cggtggtgtt cccaacactg gaccacccgg ggaaccaggc     1620

ccacctggtc catggggtct cataggcctt ccaggcctta aaggagccag aggagatcga     1680

ggctctgggg gtgcacaggg cccagcaggg gctccaggct tagttgggcc tctgggtcct     1740

tcaggaccca aaggaaagaa gggggaacca attctcagta caatccaagg aatgccagga     1800

gatcggggtg attctggctc ccagggcttc cgtggtgtaa taggagaacc aggcaaggac     1860

ggagtaccag gtttaccagg tctgccaggc cttccgggtg atggtggaca gggcttccca     1920

ggtgaaaagg ggttacctgg acttcctggt gaaaaaggcc atcctggtcc acctggcctc     1980

ccaggaaatg ggttaccagg acttcctgga ccccgtgggc ttcctggaga taaaggcaag     2040

gatggattac cgggacaaca aggccttccc ggatctaagg gaatcaccct gccctgtatt     2100

attcctgggt catacggtcc atcaggattt ccaggcactc ccggattccc aggccctaaa     2160

gggtctcgag gcctccctgg gaccccaggc cagcctgggt caagtggaag taaaggagag     2220

ccagggagtc caggattggt tcatcttcct gaattaccag gatttcctgg acctcgtggg     2280

gagaagggct tgcctgggtt tcctgggctc cctggaaaag atggcttgcc tgggatgatt     2340

ggcagtccag gcttacctgg ttccaaggga gccactggtg acatctttgg tgctgaaaat     2400

ggtgctccgg gggaacaagg cctacaagga ttaacagggc acaaaggatt tcttggagac     2460

tctggccttc caggactcaa gggtgtgcac gggaagcctg gcttactagg ccccaaaggt     2520

gagcggggca gccctgggac accaggacag gtgggacagc caggcacccc aggatctagt     2580

ggtccatatg gcatcaaggg caaatctggg ctcccaggag caccaggctt cccaggcatc     2640

tcaggacatc ctggaaagaa aggaacaaga ggcaagaaag gtcctcctgg atcaattgta     2700

aagaaagggc tgccagggct aaaaggcctt cctggaaatc caggcctagt aggactgaaa     2760

ggaagcccag gctctccagg ggtcgctggg ttgccagccc tctctggacc caagggagag     2820

aaggggtctg ttggattcgt aggttttcca ggaataccag gtctgcctgg tattcctgga     2880

acaagaggat taaaaggaat tccaggatca actggaaaaa tgggaccatc tggacgtgct     2940

ggtactcctg gtgaaaaggg agacagaggc aatccggggc cagtcggaat acctagtcca     3000

agacgtccaa tgtcaaacct ttggctcaaa ggagacaaag gctctcaagg ctcagccgga     3060

tccaatggat ttcctgggcc aagaggtgac aaaggagagg ctggtcgacc tggaccacca     3120

ggcctacctg gagctcctgg cctcccaggc attatcaaag gagttagtgg aaagccaggg     3180

ccccctggct tcatgggaat ccggggctta cctggcctga aggggtcctc tgggatcaca     3240

ggtttcccag gaatgccagg agaaagtggt tcacaaggta tcagagggtc gcctggactc     3300

ccaggagcat ctggtctccc aggcctgaaa ggagacaacg gccagacagt tgaaatttcc     3360

ggtagcccag gacccaaggg acagcctggc gaatctggtt ttaaaggcac aaaaggaaga     3420

gatggactaa taggcaatat aggcttccct ggaaacaaag gtgaagatgg aaaagttggt     3480

gtttctggag atgttggcct tcctggagct ccaggatttc caggagttgc cggcatgaga     3540

ggagaaccag gacttccagg ttcttctggt caccaagggg caattgggcc tctaggatcc     3600

cccggattaa taggacccaa aggcttccct ggatttcctg gtttacatgg actgaatggg     3660

cttccgggca ccaagggtac ccatggcact ccaggaccta gtatcaccgg tgtgcctggg     3720

cctgctggtc tccctggacc caaaggagaa aaaggatatc caggaattgg catcggagct     3780

ccagggaagc cgggcctgag agggcaaaaa ggtgatcgag gtttcccagg tctccagggc     3840

cctgctggtc tccccggtgc cccaggcatc tccttgccct cactcatagc aggacagcct     3900

ggtgaccccg ggcgaccagg cctagatgga gaacgaggcc gcccaggccc cgctggaccc     3960

ccaggtcccc ctgggccatc ctcgaatcaa ggcgacaccg gagaccctgg cttccctgga     4020

attcctggac ctaaagggcc taagggagac caaggaattc caggtttttc tggcctccct     4080

ggagagctag gactgaaagg catgagaggt gagcctggct tcatggggac tccaggcaag     4140

gttgggccac ctggagaccc aggatttccc ggaatgaagg ggaaggcagg gccaagaggc     4200

tcttctggcc tccaaggtga tcctggacaa acaccaactg cagaagctgt ccaggttcct     4260

cctggaccct tgggtctacc agggatcgat ggcatccctg gcctcactgg ggaccctggg     4320

gctcaaggcc ctgtaggcct acaaggctcc aaaggtttac ctggcatccc cggtaaagat     4380

ggccccagtg ggctcccagg cccacctggg gctcttggtg atcctggtct gcctggactg     4440

caaggccctc caggatttga aggagctcca gggcagcaag gccccttcgg gatgcctgga     4500

atgcctggcc agagcatgag agtgggctac acgttggtaa agcacagcca gtcggaacag     4560

gtgcccccgt gtcccatcgg gatgagccag ctgtgggtgg ggtacagctt actgtttgtg     4620

gaggggcaag agaaagccca caaccaggac ctgggctttg ctggctcctg tctgccccgc     4680

ttcagcacca tgcccttcat ctactgcaac atcaacgagg tgtgccacta tgccaggcgc     4740

aatgataaat cttactggct ctccactacc gcccctatcc ccatgatgcc cgtcagccag     4800

acccagattc cccagtacat cagccgctgc tctgtgtgtg aggcaccctc gcaagccatt     4860

gctgtgcaca gccaggacat caccatcccg cagtgccccc tgggctggcg cagcctctgg     4920

attgggtact ctttcctcat gcacactgcc gctggtgccg agggtggagg ccagtccctg     4980

gtctcacctg gctcctgcct agaggacttt cgggccactc ctttcatcga atgcagtggt     5040

gcccgaggca cctgccacta ctttgcaaac aagtacagtt tctggttgac cacagtggag     5100

gagaggcagc agtttgggga gttgcctgtg tctgaaacgc tgaaagctgg gcagctccac     5160

actcgagtca gtcgctgcca ggtgtgtatg aaaagcctgt agggtggcac ctgccactct     5220

gccccttgcc ctcccctgcc cctcacaaca gtcacctcac aaacctgaat ggtctgaaga     5280

aggaaggcct gagccccttt gcctgtcaag ttgtacattg gagtctcatt tgggctagac     5340

taccggacac tcgtcacccc agccctcggg tccatagaga tgagcccacc ctgctgagat     5400

ctgctgtcct gtttctgtca agctggtgct actgtttgat ttggatgatt gtgtgactat     5460

tcatggctac ctcagaaaga tttgatgggc cacaactgtc ttagactgct agctttctcc     5520

ttaccgtctt gatcggaaag ctcttcctaa tcgctaatca gtcatttctt catgtacaga     5580

ggtcagcaca cattatttgg cttaaaccag aacccagtgt ttccacactt aaattctcta     5640

accgaatatt catggatggc tcaagtctgc acagagcaag tcctcactct tcaaggaggc     5700

ccactgtgtc taggcaggca agagaattga aatgaggtgc cacccagtag cccagagtga     5760

gctttagctc tctctagaat gagcaagact gggccccaca tggcttagag aggcttgaag     5820

gccagcagct gggttggggg tggtggtcat taatggcata tggtcctaga caaaccatct     5880

cctccttgcc ggctccccct ccagccagag acagaggatg tggcctggtt caaagtaaag     5940

cagaggatgc aacaaatgtg gccaagccta tcaaaggaaa tgagaatgac agcctttttt     6000

cctgggccag aagtagaggg gtgggtgcgt aaggatgtgt gagttttgct tttgactcca     6060

ggaacaaaaa ggtaaatccc acatcccagt ttctcagaag tccctgttta ttccaaatgc     6120

catccagatg tgtgcaatgt ggcaaactga agctgcacag tgttggtttc cttgtattct     6180

gaggatgtta aagactttgt taaatggtta tccaattgct ctttcacagg tagcctatta     6240

aactatttta atatgttttt ttaaacctca taaaaatcta gcacactctt ctcttgagca     6300

gttagcagac ctaaagcaag cctgaattgg ctatgcagta cattgtattc tgtttggggg     6360

aatttgtttt agccattttc tttaattacc agttttccag aacactctta gctatgttga     6420

catgaggcag ttccttccag gtgattctgt ttccttaagt attatataaa ctgtgccaat     6480

acagacaaag cataatcaat ataatctgaa ttattgttat ctttacctcc tgagtaataa     6540

gcatggtgtc agttttgtac atagcaaata aaataaatga aatctgaaca tgtgaaaaaa     6600

aaaaaaaaaa aaaaaaaa                                                   6618


<210>  1072
<211>  10828
<212>  DNA
<213>  homo sapiens

<400>  1072
ggtaccatag agttgctctg aaaacagaag atagagggag tctcggagct cgccatctcc       60

agcgatctct acattgggaa aaaacatgga gtcagctccg gcagcccccg accccgccgc      120

cagcgagcca ggcagcagcg gcgcggacgc ggccgccggc tccagggaga ccccgctgaa      180

ccaggaatcc gcccgcaaga gcgagccgcc tgccccggtg cgcagacaga gctattccag      240

caccagcaga ggtatctcag taacgaagaa gacacataca tctcaaattg aaattattcc      300

atgcaagatc tgtggagaca aatcatcagg aatccattat ggtgtcatta catgtgaagg      360

ctgcaagggc tttttcagga gaagtcagca aagcaatgcc acctactcct gtcctcgtca      420

gaagaactgt ttgattgatc gaaccagtag aaaccgctgc caacactgtc gattacagaa      480

atgccttgcc gtagggatgt ctcgagatgc tgtaaaattt ggccgaatgt caaaaaagca      540

gagagacagc ttgtatgcag aagtacagaa acaccggatg cagcagcagc agcgcgacca      600

ccagcagcag cctggagagg ctgagccgct gacgcccacc tacaacatct cggccaacgg      660

gctgacggaa cttcacgacg acctcagtaa ctacattgac gggcacaccc ctgaggggag      720

taaggcagac tccgccgtca gcagcttcta cctggacata cagccttccc cagaccagtc      780

aggtcttgat atcaatggaa tcaaaccaga accaatatgt gactacacac cagcatcagg      840

cttctttccc tactgttcgt tcaccaacgg cgagacttcc ccaactgtgt ccatggcaga      900

attagaacac cttgcacaga atatatctaa atcgcatctg gaaacctgcc aatacttgag      960

agaagagctc cagcagataa cgtggcagac ctttttacag gaagaaattg agaactatca     1020

aaacaagcag cgggaggtga tgtggcaatt gtgtgccatc aaaattacag aagctataca     1080

gtatgtggtg gagtttgcca aacgcattga tggatttatg gaactgtgtc aaaatgatca     1140

aattgtgctt ctaaaagcag gttctctaga ggtggtgttt atcagaatgt gccgtgcctt     1200

tgactctcag aacaacaccg tgtactttga tgggaagtat gccagccccg acgtcttcaa     1260

atccttaggt tgtgaagact ttattagctt tgtgtttgaa tttggaaaga gtttatgttc     1320

tatgcacctg actgaagatg aaattgcatt attttctgca tttgtactga tgtcagcaga     1380

tcgctcatgg ctgcaagaaa aggtaaaaat tgaaaaactg caacagaaaa ttcagctagc     1440

tcttcaacac gtcctacaga agaatcaccg agaagatgga atactaacaa agttaatatg     1500

caaggtgtct acattaagag ccttatgtgg acgacataca gaaaagctaa tggcatttaa     1560

agcaatatac ccagacattg tgcgacttca ttttcctcca ttatacaagg agttgttcac     1620

ttcagaattt gagccagcaa tgcaaattga tgggtaaatg ttatcaccta agcacttcta     1680

gaatgtctga agtacaaaca tgaaaaacaa acaaaaaaat taaccgagac actttatatg     1740

gccctgcaca gacctggagc gccacacact gcacatcttt tggtgatcgg ggtcaggcaa     1800

aggaggggaa acaatgaaaa caaataaaag ttgaacttgt ttttctcatg catatgattt     1860

ccattatgcc tacagatatg gacccttttt ctgtcttgac ttcttgatca ttgacctctg     1920

tttacaacag gaggagggta ctaaagtcgg aggatttcct tttcttgtag ctcactgccc     1980

acagactttc tacagagtca ccaatctgtc agtaacaaca gagagtccag caataatcgg     2040

tgactggtgt gcatagcgga ggttgcggca ttactttgca caactagctc tttgtttcat     2100

gaaggaagtt tttatttttt caccgattat tgccagtccg caggatggca tgaaaagggt     2160

ccatagcagt agcaacaata gcattataat atattacagg gtaaatgggc atgaagacta     2220

tatatagcta aaagagatat tgtttatata ttgttttaag taatataaaa tgtagttact     2280

ggtgtagctt ttcctgttga attgataagg cactttcatt ttgcaccttt ttctttaaat     2340

taaatgctag cgtgttcact gtcgtgtcgc atgtgcacca gaaacacaag tttaactgag     2400

aaggcttgga aggtacgttg ggaggtattt atgctgctgt ttacaaaatt atttttaaga     2460

gactggctgg tcatatctag aaatcaccac gttggatttt ttttttaaca tgtgaatttg     2520

gaattagaaa cggaactctc cctaaattat actttgcttt ttggtaagtt taatgataga     2580

tgtgtttatg cttcatacaa agttgaatga ttgattggcg tggtggacat ataccatcat     2640

gctcattttt tttttttaaa gctttttaaa atgccacctc atggaggcga gggggaggag     2700

aagctcattt tacacaattc agtagttaaa tatggactcg gtctcaactt ggaattctta     2760

tgctttgaga acaaatcaac aaccagaata tttattggaa tctagctttt attataagaa     2820

ggacccaaag attatatcct gagcaaatgc acactcccca tgtgaggaca tgaagtattt     2880

actttgtgaa tgtttatgtt cttggtataa tctaggaacc ctatgagttt atctcagagt     2940

gaactaattc tagatttgtt gtcaatagat gctataattc aagaatgttg ctctccatat     3000

ttgaaaaacg atggatagga gggtgaggga agcatacaat gttgaaccag tttctcttat     3060

ttaaatatta aatactttaa gcctttaaag tgaagttgat gctagctgca aacatttact     3120

cttgtattta tcttcactag gaaactgtgg actgtaattt attttattaa atatttagaa     3180

gattatttgg cttgtgtgtt caggtgagaa atactgagtt gtttttgttt aatttcatgg     3240

tttttttttt tttaatgatc cctagtgggg gaaggggaaa ggaatagtct gataaacaga     3300

tgtgcatatt ttaaaaacaa gtgacctttt gggaatgtag gcatttagac gatgatttta     3360

gtcgcactag gggtgggatt caaactactg gtcaaagacc attttgtaca gaaaagggaa     3420

catctccgat gggtgttaag gtaggagttt ccatgcagcc ctttatgtct gagaaatagt     3480

ctcctctgcc attggggtcc ctgcggaatc ttctacagga attgcagctc ttcacgtcat     3540

gctaggttac cagcatgggc ttcccagagc acttcactct gtttctaact ccactgactt     3600

ttctgacttg tttcttgagg gacttggaaa aggggaaggt attattcaca cagatgtgtg     3660

tatgaagcct aaataacatc caactttttt tccaaaaaca tagtaagagt ttaaccataa     3720

atagaagagt aatattcctt taaatttctt acaggcatgt aaaattttat gtgtttatag     3780

agagatgcta actgtcagca tatagtattt atattggggc aagaagggtt aaatcaaatc     3840

tttaatttaa gtaagcatag ttcctttaaa gatcagtagt atttatactc tgaaaagagt     3900

accaagctta gttcagttat ttattcatcc attttttttc tattgtttct cctctggggg     3960

gaaatggtgt tttgtttttg tttgagtttt gtgttttagt tttttggttt tggttttgtt     4020

ttgttttttt gtcattcaga ttcactaaat ttggggatgg ttttattaaa gtatattaac     4080

ttctttttaa ccaaagcttt ctgaatatga ccagcctcag gtgctagcgc attaaagagc     4140

aactaaacct aattccagtg tcgatttgtg aaataataaa agctaattga atttctctaa     4200

gggtgagaga gaacataatg atgaacttaa aaagaaattc cttttcccag aagggattct     4260

gcatgtacct acaaacaatc atgctctaac cacagtaata gtcatgccat ggtgacattg     4320

cttttacggt aaaccaagat aggtaatatg atgcttcttc ccaggtgttt ctgaaagaaa     4380

agcagcggtg gagcttaaga gccaagtcca ctgattgaca taataggatg gaattgtaga     4440

cagagacatg ctccatgaaa caaggaaaca actgactact atttggatct aagttgggat     4500

ctgatgttaa acaataaatt cagtttaaaa aaaatatgga gctcagaaaa ggatgtgaaa     4560

aactttgcat tttcctttct tcattattac aaaaacacct atgtgatgac ataaaatact     4620

tgggtgatat cagaacaatt atccttaata gtttttataa ttaaagtttc ctaaacttca     4680

gtctccaata gtcttttaag gattggaacc acatcactgt cagccccgct gctacaatgc     4740

ctttgtacaa tttttttaca taaggcaaat aaggcttttg tacaaagcct gaataccttc     4800

tgttccaatg gtgtccaaat ggttattata ttgtgaaaaa cctggccttg gtcacaatgc     4860

aaacaaaagt acagatgaaa gtgctttttg gacagtttgc aaattgtgtt aaagctacgg     4920

atttttttta aagtgttcag catcttaacg tgtattaaag ctatggattt ttttttaaag     4980

tcttcagcat cctaattcac cctttctaac ttaagaaaaa catgacttaa gacactgctt     5040

ctaagtttgg ttgttcttta tagtgtggat acccagttat ctgtgagcgt atgggggtgg     5100

gctgagggtc aggtgaggaa ggagtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg     5160

tgatttgcat gtgtatgatg tgtgtgcgtc ggaccgcttc taggctacta agtgtcaatg     5220

gaaaagaaaa tgtattcaaa atacttaaat caaaactaga agatggggaa aaaaagattt     5280

attctataca aagccttgtc tggaccactt tagagagact tctatttttt taacccttct     5340

ataaatattt gatggcactt gaaatattcc tgcaataaaa tgtgatttgt gtaaagaaaa     5400

aaagattttg taatgtgaaa caaagaaaga aagtaatgta attttctaaa aaaaaaaata     5460

caaacaaaca aactttgtat tattttcttg atggaatttg tctatctgtc tttggaaaac     5520

tttttatttc attgaatgtg ccatagtaga aatgtgtgtt tttagtttta gactaaggaa     5580

tagctagttg ttgtgttccg acattccaaa atgcaaaaca acctagtagt atctttcatg     5640

aaaaggttta agtagtatgt aagcttctct cattgttgct tttttgcaca tgttcttcat     5700

tcctctctag tgcaatatgt acatagagca cttgcgggtg taccttgatc cctcagggaa     5760

aaatacatat ttgtacagtt ttttggggtt tttttgtttt ttggtttttt ttgttttgcc     5820

ttttgttttt ggctaaggaa tgtcgatcga atcacttgtt attgttgagg ggcagccaga     5880

taataatcct aaagccactg tttccaacat tgattgttta aatcatatgt ccttccaatg     5940

ctattatttt aagataataa taaaaagtta ttttctgaca gttctttgtg ctgactggtg     6000

aaaaacaagg gtaaataagc accttataat tgacttactg tgaatgacaa tccatcttgg     6060

tatcaacgat agaagcccta tcattttgga gttggggtta agagtcagaa acaatgtgct     6120

cagggatctc ctaaaactct taaaacaggg tggccagtac tactgggaca aattgtgttt     6180

tttattatta ataataatga taataatact atccctccaa ggcacaagtg aactatatag     6240

aactgcgtgt gtgtaaactc tttactctcg tctcattttg ttgagtttag aacttgatgt     6300

gctcgtcagt cttgtgtttc aaaacactga ataacttcca aagcaaagtt atgccagtgt     6360

gttcaaaaga taaattaata atgtaccagc aaagagcatc attcaaagta tagtccttgc     6420

atattccagt taccatttct ctaataatta aaatattcat gataaatata tatatagcat     6480

catatgttaa aaactatttc aaattctaca tattaaggat gaaaatttta aaatccagta     6540

ataagaggag agacctgcct atcagtacag tgatataggt aaaagatgaa atatgttttt     6600

aaaataccag caattaacta ttgttttcat gggttctcct ctagaagcaa accaaaaatt     6660

ccttcatgga aaacaattct tacttctaca tgtgtagttt atatctgatg cattacaaga     6720

gctaatgttt aaagacaaaa caaaacctgc ctgtatgaca gcagcaactc gagccaacat     6780

ttagtgttac atgttatatt tttgaaatac cgttttgtta tcatattcca catattactt     6840

tccataaagt cagagaagtt caatgtaatt gttggctctg attcttccac cttgggatac     6900

acattcacaa gaagatttat atattttctt actatgatag aggaacataa tctgggaaaa     6960

cttcccatgt ctgtaagatg aaaaggatac ctttaccatg ttgtttttga taataaagaa     7020

tatggaaaat ggtagaaatc tctcctctct atgtgtattt gtatatgtgt gtatacacac     7080

acacgttgac atttttacat aacatgtgat tgccacttct tataaagtta tgatatagaa     7140

ccccatgaaa acaactttat attatagatc aaataatgtg cccagaaacg caattgcaac     7200

agtaaatctt gatctattgg taagagtcta tgatacaggt cttcattcta tccctaaaca     7260

taatgttagt aaagaggttc catcagattg tattatagag accttcctat tgctatttat     7320

ttttaagaga tgagaagact gactagcaat gtctccacag tgcaattggt ttcacttctg     7380

ggtctgtctg tctgtttgtg taggtgagat cagtgttgtc aggctctcag aataattttt     7440

aaaagaatcc agaagcctga cttcacacca agtagccatc ctagatgggc gggggggatc     7500

tccatgttca accaaaccct cagaacttag agcaataaat acattcagtc atttatttat     7560

aaatgaatga cagaatattc aatccaaata gaaacaacct tttgtcagtg atgcaacata     7620

acatggagtc ttatattgag aaagtgaata tgaatatttt aaatagatgc ctaggaaatc     7680

tgtgtttgct gtttacattt aatgtacttt gccacattag cagtaccaca cttcttttac     7740

tttcatcctt ctaagaacta atgaaagata gcttgctatt agctttgaca tgttgcacat     7800

gccattatgt tgttctctaa gaacaactaa attctctcca gtgttcatgt gtgattcctt     7860

tttcatcatt attactttaa tgtggatgaa tactatttct aggaacttga ttatcactga     7920

acagattgca tatgtaaatg cagataattc ttgagcaata tagtgaaaat gatttcacaa     7980

aaaaaatcca tatgtactgt atacatcttc ctgaatccaa aattctcctg ttatccacac     8040

agtttgaaat ctcatattaa acagtggtaa atttttaaac attaggacat tagctggctg     8100

cttctataaa tgtacctgta ttgtctgcct gctccttttg tggagatgtg tttttgtatt     8160

ggatgtttgg gccaatggga ggcttcaagc tacaacatat tttcccactt taaataatat     8220

ttaacatatg acaaacccca gacaaggctt ttaatatgta taaagaactg cagtgttagg     8280

tggtttattt gcaaactgtt ttcagtgttg tccattttta tggcaccttt aacaatattc     8340

ttgtttccaa agtacaaaaa aaataggtta aataatctag ccataactga atgtcaagca     8400

ataaaacaaa tgacttttgt gcatagactt aaaaaataca aattttagac atctgcatgt     8460

aaatgcaatc tcttgtttac tgctttcttc aacttgagca atcgattcct tatttactat     8520

taacttaaga acttgtaacg gcctgtaaac attttctctc ttactcttct ttcaaattta     8580

cctgtccctg cttttgagtc ataatattta atgttgttct gcacatctct atacagttaa     8640

ctttttggct ttcattctgt atagataaga aaatgttata ttataaacag cctactcagt     8700

gcaaatattt atctgtttat caaatccaca atatgctgta taataccggt tttactatat     8760

aatctatttt agacatagct gtttagaact agagtgtgct atttttgtgt ttttctgatg     8820

tgtggtgcta gacaagttac ttttgtgaac aacaaaaatt atccctttta ttcctagaca     8880

ataccacctt tgggtcttgt taatttcact gagtataact atatatttgt atatatatac     8940

atatatatat atatctacct atgcccaact ggcagctgta tcagagtgct ggatttggga     9000

catgcttttc tctttaaata cataatatca ttatataaat tattctagag tgtatttaat     9060

taggataaaa ttacttcctt agtatggata tttgacatct atagggtgaa tttgtttata     9120

aatatggcta tatggaaact tattagcatt tactttatgt ttgctacttg gctttacagc     9180

atatctccta agctgaaaaa taatttgcca ggccttcaag atcctaaaga aacttgttta     9240

atggagtaat atactttttt ttcttattaa ggaattgtat tactggcacc taacacagtt     9300

gtattcttag ctcctattat agataatggg catttacata aaatatccta gatggcttga     9360

tggcagaata aacctttccc ctcctacctg agtcatgaga aggatggaga cgtcctctgc     9420

cataacatgg gccataaagc aaattcgaca tgggatgttc tgtttcagta tgacctcaac     9480

cagttccatg aactgagtga aggaccttca ttttcaaagt tatttaataa gtagcttaat     9540

taagcctttc tacccattct cccaagatct actggcatta ttgaaaagca aagtttatca     9600

aatatctaac taaggatgta gttaacctta ttaaatattg attagaattg ttctgtaata     9660

ttactgaatt tgtaagatct ttagcaaaga tttttgagca atttataaat gtagagcaaa     9720

tgtttctgtt tactgcactt tttgtaactg aaggtgataa attctcaagc catgattatt     9780

ggcttccatg cactgcaata tttatccaca attctagaca ttttccattt ttgtggaaga     9840

gttgctgtta ccttaattat aaatgcaatt gtgtggttaa tgagagctaa tgctagtagt     9900

taacctttta aagtggattg gctacagttg agggagaaat ctcttttaat ataaatcaca     9960

tcattcctta actgcctctc ttggaaagag attgaaacct tttttttaaa gcacgattta    10020

gcatcctaag cttcctgagg gtagagattg tatctttttg cgtctgcaca atggctagca    10080

catgtcagca tttgacaatt gttaaatgat aacaagtgtg ccccaattaa aacgtttttc    10140

ctgggttgtt ttgttaaatt tacaaagtaa gccaagcctt acggttaaca ttctcctcta    10200

caaccaagta ttaaagccac atttaaaaag accacatgaa atgctgattc taattgtgtg    10260

taggtcttga ggattaagca cacaaatttc acaaacttct gtttgagtaa acaaactcag    10320

ccttctgtaa atatacatgc aagtttggaa acagtaatac tgtacctata aatatatgct    10380

gtctgttttg tgtacagtat gtaaaaactc cttttctgcc acactaaaaa tgcaagccat    10440

ttatgggaat cctaaaacta gtattgaact aaaactttgc taatgatctt tattagagga    10500

tcgtccaact tttcacttac cttgggtttt cttttcaatt cactcttaca ctagtctgct    10560

tatttccagc tgtttatttt attgagtcct gaatttaaaa aaaaaatatt ttgattcatt    10620

ttgtaaatac aagctgtaca aaaaagagag atttaatgtt gtcttttaaa tactccaatt    10680

ttcattctaa tatgaatgtt gttatattgt acttagaaac tgtaccttta atattacatt    10740

acctttatta aaagtgcatt gaacacatca attttagatg tgctttatgt actgttatcc    10800

tataataaaa cttcagcttc taatggaa                                       10828


<210>  1073
<211>  3793
<212>  DNA
<213>  homo sapiens

<400>  1073
gattcgggcc ggctcgcggg cgctgccagt ctcgggcggc ggtgtccggc gcgcgggcgg       60

cctgctgggc gggctgaagg gttagcggag cacgggcaag gcggagagtg acggagtcgg      120

cgagcccccg cggcgacagg ttctctactt aaaagacaat gactactgat gaaggtgcca      180

agaacaatga agaaagcccc acagccactg ttgctgagca gggagaggat attacctcca      240

aaaaagacag gggagtatta aagattgtca aaagagtggg gaatggtgag gaaacgccga      300

tgattggaga caaagtttat gtccattaca aaggaaaatt gtcaaatgga aagaagtttg      360

attccagtca tgatagaaat gaaccatttg tctttagtct tggcaaaggc caagtcatca      420

aggcatggga cattggggtg gctaccatga agaaaggaga gatatgccat ttactgtgca      480

aaccagaata tgcatatggc tcggctggca gtctccctaa aattccctcg aatgcaactc      540

tcttttttga gattgagctc cttgatttca aaggagagga tttatttgaa gatggaggca      600

ttatccggag aaccaaacgg aaaggagagg gatattcaaa tccaaacgaa ggagcaacag      660

tagaaatcca cctggaaggc cgctgtggtg gaaggatgtt tgactgcaga gatgtggcat      720

tcactgtggg cgaaggagaa gaccacgaca ttccaattgg aattgacaaa gctctggaga      780

aaatgcagcg ggaagaacaa tgtattttat atcttggacc aagatatggt tttggagagg      840

cagggaagcc taaatttggc attgaaccta atgctgagct tatatatgaa gttacactta      900

agagcttcga aaaggccaaa gaatcctggg agatggatac caaagaaaaa ttggagcagg      960

ctgccattgt caaagagaag ggaaccgtat acttcaaggg aggcaaatac atgcaggcgg     1020

tgattcagta tgggaagata gtgtcctggt tagagatgga atatggttta tcagaaaagg     1080

aatcgaaagc ttctgaatca tttctccttg ctgcctttct gaacctggcc atgtgctacc     1140

tgaagcttag agaatacacc aaagctgttg aatgctgtga caaggccctt ggactggaca     1200

gtgccaatga gaaaggcttg tataggaggg gtgaagccca gctgctcatg aacgagtttg     1260

agtcagccaa gggtgacttt gagaaagtgc tggaagtaaa cccccagaat aaggctgcaa     1320

gactgcagat ctccatgtgc cagaaaaagg ccaaggagca caacgagcgg gaccgcagga     1380

tatacgccaa catgttcaag aagtttgcag agcaggatgc caaggaagag gccaataaag     1440

caatgggcaa gaagacttca gaaggggtca ctaatgaaaa aggaacagac agtcaagcaa     1500

tggaagaaga gaaacctgag ggccacgtat gacgccacgc caaggaggga agagtcccag     1560

tgaactcggc ccctcctcaa tgggctttcc cccaactcag gacagaacag tgtttaatgt     1620

aaagtttgtt atagtctatg tgattctgga agcaaatggc aaaaccagta gcttcccaaa     1680

aacagccccc ctgctgctgc ccggagggtt cactgagggg tggcacggga ccactccagg     1740

tggaacaaac agaaatgact gtggtgtgga gggagtgagc cagcagctta agtccagctc     1800

atttcagttt ctatcaacct tcaagtatcc aattcagggt ccctggagat catcctaaca     1860

atgtggggct gttaggtttt acctttgaac tttcatagca ctgcagaaac ctttaaaaaa     1920

aaaatgcttc atgaatttct cctttcctac agttgggtag ggtaggggaa ggaggataag     1980

cttttgtttt ttaaatgact gaagtgctat aaatgtagtc tgttgcattt ttaaccaaca     2040

gaacccacag tagaggggtc tcatgtctcc ccagttccac agcagtgtca cagacgtgaa     2100

agccagaacc tcagaggcca cttgcttgct gacttagcct cctcccaaag tccccctcct     2160

cagccagcct ccttgtgaga gtggctttct accacacaca gcctgtccct gggggagtaa     2220

ttctgtcatt cctaaaacac ccttcagcaa tgataatgag cagatgagag tttctggatt     2280

agcttttcct attttcgatg aagttctgag atactgaaat gtgaaaagag caatcagaat     2340

tgtgcttttt ctcccctcct ctattccttt tagggaataa tattcaatac acagtacttc     2400

ctcccagcat tgctactgct cagcttcttc tttcattcta atccttgcta ttaagaattt     2460

aagacttgtg cttacaatat ttttgacctg gagtggatct atttacatag tcatttagga     2520

tccatgcagc tttttttgtc tttttaagat tattggctca taagcatatg tatactggtt     2580

tatggaactt tatttacact cctctatcat gcaaaaaaat tttgactttt tagtactaag     2640

cttaattttt aaaaacaaaa tctgtagggt tgacaaataa atagttgctc ttctacacta     2700

ggggtttcac ctgcaggttt gacacgcagt tgctcgcttt tcctgccctg tcaagcttct     2760

ctgttctggc gtgagttgtg aaagagttga agacagcttc ccatgccggt acacagccag     2820

tagcctaaat ctccagtact tgagctgacc attgaactag ggcaagtctt aaatgtgtac     2880

atgtagttga atttcagtcc ttacgggtaa acagattgag catggctctc tattccctca     2940

gcctaagaaa cactcatggg aatgcatttg gcaacccaag gaaccatttg cttaaacctg     3000

gaacatctca cctttttaaa tcctaaaaaa cactggcagt tatattttaa attagttttt     3060

atttttatga tggttttatc aaaagacttt tattattaga ttgggacccc cttcaaacct     3120

aaaaatcaag ttatttcctt ttataatact tttcttcccc atggaacaaa tgggatcaat     3180

ttgtgagttt tttcctttaa tgataactaa aatccctcta atttctcatt tatgcttttg     3240

tcttttttat gaaatatttc ttttaaaagc cccagtctca cctacgaaat atgaagagca     3300

aaagctgatt ttgcttactt gctaaactgt tgggaaagct ctgtagagca tggttccagt     3360

gaggccaaga ttgaaatttg atactaaaaa ggccacctag ctttttgcag ataacaaaca     3420

agaaagctat tccaagactc agatgatgcc agctgtctcc cacgtgtgta ttatggttca     3480

ccagggggaa ctggcaaaag tgtgtgtggg gaggggaagg gtgtgtgagt ggttctgagc     3540

aaataactac agggtgccca ttaccactca agaagacact tcacgtattc ttgtatcaaa     3600

ttcaataatc ttaaacaatt tgtgtagaag tccacagaca tctttcaacc accttttagg     3660

ctgcatatgg attgccaagt cagcatatga ggaattaaag acattgtttt taaaaaaaaa     3720

aaatcattta gatgcacttt tttgtgtgtt ctttaaataa atccaaaaaa aatgtgactt     3780

ccaaaaaaaa aaa                                                        3793


<210>  1074
<211>  3838
<212>  DNA
<213>  homo sapiens

<400>  1074
agtctcgggc ggcggtgtcc ggcgcgcggg cggcctgctg ggcgggctga agggttagcg       60

gagcacgggc aaggcggaga gtgacggagt cggcgagccc ccgcggcgac aggtaccggc      120

gccatggcca cggagatggg gcggccggcc gcggcgcccc gggagccgaa cgccctcctt      180

ccaggttctc tacttaaaag acaatgacta ctgatgaagg tgccaagaac aatgaagaaa      240

gccccacagc cactgttgct gagcagggag aggatattac ctccaaaaaa gacaggggag      300

tattaaagat tgtcaaaaga gtggggaatg gtgaggaaac gccgatgatt ggagacaaag      360

tttatgtcca ttacaaagga aaattgtcaa atggaaagaa gtttgattcc agtcatgata      420

gaaatgaacc atttgtcttt agtcttggca aaggccaagt catcaaggca tgggacattg      480

gggtggctac catgaagaaa ggagagatat gccatttact gtgcaaacca gaatatgcat      540

atggctcggc tggcagtctc cctaaaattc cctcgaatgc aactctcttt tttgagattg      600

agctccttga tttcaaagga gaggatttat ttgaagatgg aggcattatc cggagaacca      660

aacggaaagg agagggatat tcaaatccaa acgaaggagc aacagtagaa atccacctgg      720

aaggccgctg tggtggaagg atgtttgact gcagagatgt ggcattcact gtgggcgaag      780

gagaagacca cgacattcca attggaattg acaaagctct ggagaaaatg cagcgggaag      840

aacaatgtat tttatatctt ggaccaagat atggttttgg agaggcaggg aagcctaaat      900

ttggcattga acctaatgct gagcttatat atgaagttac acttaagagc ttcgaaaagg      960

ccaaagaatc ctgggagatg gataccaaag aaaaattgga gcaggctgcc attgtcaaag     1020

agaagggaac cgtatacttc aagggaggca aatacatgca ggcggtgatt cagtatggga     1080

agatagtgtc ctggttagag atggaatatg gtttatcaga aaaggaatcg aaagcttctg     1140

aatcatttct ccttgctgcc tttctgaacc tggccatgtg ctacctgaag cttagagaat     1200

acaccaaagc tgttgaatgc tgtgacaagg cccttggact ggacagtgcc aatgagaaag     1260

gcttgtatag gaggggtgaa gcccagctgc tcatgaacga gtttgagtca gccaagggtg     1320

actttgagaa agtgctggaa gtaaaccccc agaataaggc tgcaagactg cagatctcca     1380

tgtgccagaa aaaggccaag gagcacaacg agcgggaccg caggatatac gccaacatgt     1440

tcaagaagtt tgcagagcag gatgccaagg aagaggccaa taaagcaatg ggcaagaaga     1500

cttcagaagg ggtcactaat gaaaaaggaa cagacagtca agcaatggaa gaagagaaac     1560

ctgagggcca cgtatgacgc cacgccaagg agggaagagt cccagtgaac tcggcccctc     1620

ctcaatgggc tttcccccaa ctcaggacag aacagtgttt aatgtaaagt ttgttatagt     1680

ctatgtgatt ctggaagcaa atggcaaaac cagtagcttc ccaaaaacag cccccctgct     1740

gctgcccgga gggttcactg aggggtggca cgggaccact ccaggtggaa caaacagaaa     1800

tgactgtggt gtggagggag tgagccagca gcttaagtcc agctcatttc agtttctatc     1860

aaccttcaag tatccaattc agggtccctg gagatcatcc taacaatgtg gggctgttag     1920

gttttacctt tgaactttca tagcactgca gaaaccttta aaaaaaaaat gcttcatgaa     1980

tttctccttt cctacagttg ggtagggtag gggaaggagg ataagctttt gttttttaaa     2040

tgactgaagt gctataaatg tagtctgttg catttttaac caacagaacc cacagtagag     2100

gggtctcatg tctccccagt tccacagcag tgtcacagac gtgaaagcca gaacctcaga     2160

ggccacttgc ttgctgactt agcctcctcc caaagtcccc ctcctcagcc agcctccttg     2220

tgagagtggc tttctaccac acacagcctg tccctggggg agtaattctg tcattcctaa     2280

aacacccttc agcaatgata atgagcagat gagagtttct ggattagctt ttcctatttt     2340

cgatgaagtt ctgagatact gaaatgtgaa aagagcaatc agaattgtgc tttttctccc     2400

ctcctctatt ccttttaggg aataatattc aatacacagt acttcctccc agcattgcta     2460

ctgctcagct tcttctttca ttctaatcct tgctattaag aatttaagac ttgtgcttac     2520

aatatttttg acctggagtg gatctattta catagtcatt taggatccat gcagcttttt     2580

ttgtcttttt aagattattg gctcataagc atatgtatac tggtttatgg aactttattt     2640

acactcctct atcatgcaaa aaaattttga ctttttagta ctaagcttaa tttttaaaaa     2700

caaaatctgt agggttgaca aataaatagt tgctcttcta cactaggggt ttcacctgca     2760

ggtttgacac gcagttgctc gcttttcctg ccctgtcaag cttctctgtt ctggcgtgag     2820

ttgtgaaaga gttgaagaca gcttcccatg ccggtacaca gccagtagcc taaatctcca     2880

gtacttgagc tgaccattga actagggcaa gtcttaaatg tgtacatgta gttgaatttc     2940

agtccttacg ggtaaacaga ttgagcatgg ctctctattc cctcagccta agaaacactc     3000

atgggaatgc atttggcaac ccaaggaacc atttgcttaa acctggaaca tctcaccttt     3060

ttaaatccta aaaaacactg gcagttatat tttaaattag tttttatttt tatgatggtt     3120

ttatcaaaag acttttatta ttagattggg acccccttca aacctaaaaa tcaagttatt     3180

tccttttata atacttttct tccccatgga acaaatggga tcaatttgtg agttttttcc     3240

tttaatgata actaaaatcc ctctaatttc tcatttatgc ttttgtcttt tttatgaaat     3300

atttctttta aaagccccag tctcacctac gaaatatgaa gagcaaaagc tgattttgct     3360

tacttgctaa actgttggga aagctctgta gagcatggtt ccagtgaggc caagattgaa     3420

atttgatact aaaaaggcca cctagctttt tgcagataac aaacaagaaa gctattccaa     3480

gactcagatg atgccagctg tctcccacgt gtgtattatg gttcaccagg gggaactggc     3540

aaaagtgtgt gtggggaggg gaagggtgtg tgagtggttc tgagcaaata actacagggt     3600

gcccattacc actcaagaag acacttcacg tattcttgta tcaaattcaa taatcttaaa     3660

caatttgtgt agaagtccac agacatcttt caaccacctt ttaggctgca tatggattgc     3720

caagtcagca tatgaggaat taaagacatt gtttttaaaa aaaaaaaatc atttagatgc     3780

acttttttgt gtgttcttta aataaatcca aaaaaaatgt gacttccaaa aaaaaaaa       3838


<210>  1075
<211>  3122
<212>  DNA
<213>  homo sapiens

<400>  1075
aatagactaa acccagagcc tcaaagcagt gcactccgtg aaggcaaaga gaacacgctg       60

caaaaggctt tccaagaatc ctcgacatgg caaggaggag ctcgttccag tcgtgtcaga      120

taatatccct gttcactttt gccgttggag tcaatatctg cttaggattc actgcacatc      180

gaattaagag agcagaagga tgggaggaag gtcctcctac agtgctatca gactccccct      240

ggaccaacat ctccggatct tgcaagggca ggtgctttga acttcaagag gctggacctc      300

ctgattgtcg ctgtgacaac ttgtgtaaga gctataccag ttgctgccat gactttgatg      360

agctgtgttt gaagacagcc cgtggctggg agtgtactaa ggacagatgt ggagaagtca      420

gaaatgaaga aaatgcctgt cactgctcag aggactgctt ggccagggga gactgctgta      480

ccaattacca agtggtttgc aaaggagagt cgcattgggt tgatgatgac tgtgaggaaa      540

taaaggccgc agaatgccct gcagggtttg ttcgccctcc attaatcatc ttctccgtgg      600

atggcttccg tgcatcatac atgaagaaag gcagcaaagt catgcctaat attgaaaaac      660

taaggtcttg tggcacacac tctccctaca tgaggccggt gtacccaact aaaacctttc      720

ctaacttata cactttggcc actgggctat atccagaatc acatggaatt gttggcaatt      780

caatgtatga tcctgtattt gatgccactt ttcatctgcg agggcgagag aaatttaatc      840

atagatggtg gggaggtcaa ccgctatgga ttacagccac caagcaaggg gtgaaagctg      900

gaacattctt ttggtctgtt gtcatccctc acgagcggag aatattaacc atattgcagt      960

ggctcaccct gccagatcat gagaggcctt cggtctatgc cttctattct gagcaacctg     1020

atttctctgg acacaaatat ggccctttcg gccctgagat gacaaatcct ctgagggaaa     1080

tcgacaaaat tgtggggcaa ttaatggatg gactgaaaca actaaaactg catcggtgtg     1140

tcaacgtcat ctttgtcgga gaccatggaa tggaagatgt cacatgtgat agaactgagt     1200

tcttgagtaa ttacctaact aatgtggatg atattacttt agtgcctgga actctaggaa     1260

gaattcgatc caaatttagc aacaatgcta aatatgaccc caaagccatt attgccaatc     1320

tcacgtgtaa aaaaccagat cagcacttta agccttactt gaaacagcac cttcccaaac     1380

gtttgcacta tgccaacaac agaagaattg aggatatcca tttattggtg gaacgcagat     1440

ggcatgttgc aaggaaacct ttggatgttt ataagaaacc atcaggaaaa tgctttttcc     1500

agggagacca cggatttgat aacaaggtca acagcatgca gactgttttt gtaggttatg     1560

gctcaacatt taagtacaag actaaagtgc ctccatttga aaacattgaa ctttacaatg     1620

ttatgtgtga tctcctggga ttgaagccag ctcctaataa tgggacccat ggaagtttga     1680

atcatctcct gcgcactaat accttcaggc caaccatgcc agaggaagtt accagaccca     1740

attatccagg gattatgtac cttcagtctg attttgacct gggctgcact tgtgatgata     1800

aggtagagcc aaagaacaag ttggatgaac tcaacaaacg gcttcataca aaagggtcta     1860

cagaagagag acacctcctc tatgggcgac ctgcagtgct ttatcggact agatatgata     1920

tcttatatca cactgacttt gaaagtggtt atagtgaaat attcctaatg ccactctgga     1980

catcatatac tgtttccaaa caggctgagg tttccagcgt tcctgaccat ctgaccagtt     2040

gcgtccggcc tgatgtccgt gtttctccga gtttcagtca gaactgtttg gcctacaaaa     2100

atgataagca gatgtcctac ggattcctct ttcctcctta tctgagctct tcaccagagg     2160

ctaaatatga tgcattcctt gtaaccaata tggttccaat gtatcctgct ttcaaacggg     2220

tctggaatta tttccaaagg gtattggtga agaaatatgc ttcggaaaga aatggagtta     2280

acgtgataag tggaccaatc ttcgactatg actatgatgg cttacatgac acagaagaca     2340

aaataaaaca gtacgtggaa ggcagttcca ttcctgttcc aactcactac tacagcatca     2400

tcaccagctg tctggatttc actcagcctg ccgacaagtg tgacggccct ctctctgtgt     2460

cctccttcat cctgcctcac cggcctgaca acgaggagag ctgcaatagc tcagaggacg     2520

aatcaaaatg ggtagaagaa ctcatgaaga tgcacacagc tagggtgcgt gacattgaac     2580

atctcaccag cctggacttc ttccgaaaga ccagccgcag ctacccagaa atcctgacac     2640

tcaagacata cctgcataca tatgagagcg agatttaact ttctgagcat ctgcagtaca     2700

gtcttatcaa ctggttgtat atttttatat tgtttttgta tttattaatt tgaaaccagg     2760

acattaaaaa tgttagtatt ttaatcctgt accaaatctg acatattatg cctgaatgac     2820

tccactgttt ttctctaatg cttgatttag gtagccttgt gttctgagta gagcttgtaa     2880

taaatactgc agcttgagtt tttagtggaa gcttctaaat ggtgctgcag atttgatatt     2940

tgcattgagg aaatattaat tttccaatgc acagttgcca catttagtcc tgtactgtat     3000

ggaaacactg attttgtaaa gttgccttta tttgctgtta actgttaact atgacagata     3060

tatttaagcc ttataaacca atcttaaaca taataaatca cacattcagt tttttctggt     3120

tt                                                                    3122


<210>  1076
<211>  4596
<212>  DNA
<213>  homo sapiens

<400>  1076
ggtcaccggg tgaggaccgg ggcggagggt gttaagttac agggcaggag cccgggtccc       60

tccgcgggca ggaaggggag ggcccatcgg ggctagggga accccggcgc agacctgggg      120

tggggtcgga aaagctgttt catcgcccgc tcccgggccc tccgctccct ccctccctcc      180

ctctctccct ggcaggactc cccgccaggc ctccccgcca ctctccgcgg cgcattccgg      240

gaggcagcgg ccgcagcggc ctcgccatgt cccagcccgg ccagaagccc gccgcctccc      300

cgcggccccg gcgagcagcc gccgcccgcc gcacccatga gcatgtcagt gaaaaaacca      360

gtgaatcgcc ttccaaacca ggagaaaaga aaggatcaga tgagaaaaaa gcagcaagcc      420

tcggcagcag tcaatcctcc agaacctatg ctggtggaac agcctcggcc accaaggtgt      480

cagcttcctc tggtgcaacc agcaagtctt ccagtatgaa tcccacagaa accaaggctg      540

taaaaacaga acctgagaag aagtcacagt caaccaagcc aaaaagccta cccaagcagg      600

catcagatac aggaagtaac gatgctcaca ataaaaaagc agtttccaga tcagctgaac      660

agcagccatc agagaaatca acagaaccaa agactaaacc acaagacatg atttctgctg      720

gtggagagag tgttgctggt atcactgcaa tatctggcaa gccgggtgac aagaaaaaag      780

aaaagaaatc attaacccca gctgtgccag ttgaatctaa accggataaa ccatcgggaa      840

agtcaggcat ggatgctgct ttggatgact taatagatac tttaggagga cctgaagaaa      900

ctgaagaaga aaatacaacg tatactggac cagaagtttc agatccaatg agttccacct      960

acatagagga attgggtaaa agagaagtca caattcctcc aaaatatagg gaactattgg     1020

ctaaaaagga agggatcaca gggcctcctg cagactcttc gaaacccata gggccagatg     1080

atgctataga cgccttgtca tctgacttca cctgtgggtc gcctacagct gctggaaaga     1140

aaactgaaaa agaggaatct acagaagttt taaaagctca gtcagcaggg acagtcagaa     1200

gtgctgctcc accccaagag aagaaaagaa aggtggagaa ggatacaatg agtgatcaag     1260

cactcgaggc tctgtcggct tcactgggca cccggcaagc agaacctgag ctcgacctcc     1320

gctcaattaa ggaagtcgat gaggcaaaag ctaaagaaga aaaactagag aagtgtggtg     1380

aggatgatga aacaatccca tctgagtaca gattaaaacc agccacggat aaagatggaa     1440

aaccactatt gccagagcct gaagaaaaac ccaagcctcg gagtgaatca gaactcattg     1500

atgaactttc agaagatttt gaccggtctg aatgtaaaga gaaaccatct aagccaactg     1560

aaaagacaga agaatctaag gccgctgctc cagctcctgt gtcggaggct gtgtgtcgga     1620

cctccatgtg tagtatacag tcagcacccc ctgagccggc taccttgaag ggcacagtgc     1680

cagatgatgc tgtagaagcc ttggctgata gcctggggaa aaaggaagca gatccagaag     1740

atggaaaacc tgtgatggat aaagtcaagg agaaggccaa agaagaagac cgtgaaaagc     1800

ttggtgaaaa agaagaaaca attcctcctg attatagatt agaagaggtc aaggataaag     1860

atggaaagcc actcctgcca aaagagtcta aggaacagct tccacccatg agtgaagact     1920

tccttctgga tgctttgtct gaggacttct ctggtccaca aaatgcttca tctcttaaat     1980

ttgaagatgc taaacttgct gctgccatct ctgaagtggt ttcccaaacc ccagcttcaa     2040

cgacccaagc tggagcccca ccccgtgata cctcgcagag tgacaaagac ctcgatgatg     2100

ccttggataa actctctgac agtctaggac aaaggcagcc tgacccagat gagaacaaac     2160

caatggaaga taaagtaaag gaaaaagcta aagctgaaca tagagacaag cttggagaaa     2220

gagatgacac tatcccacct gaatacagac atctcctgga tgataatgga caggacaaac     2280

cagtgaagcc acctacaaag aaatcagagg attcaaagaa acctgcagat gaccaagacc     2340

ccattgatgc tctctcagga gatctggaca gctgtccctc cactacagaa acctcacaga     2400

acacagcaaa ggataagtgc aagaaggctg cttccagctc caaagcacct aagaatggag     2460

gtaaagcgaa ggattcagca aagacaacag aggaaacttc caagccaaaa gatgactaaa     2520

gaaatacaag ttaaggtatc tggtatctgc atgtaaaatc ttcagctggt ggatggtgac     2580

ttttgaagaa caaaaggctt tggcaacaga aaacaattgt tctgggtgat ttctagaatg     2640

gtttttgttg agtctctgaa catcctaaat attggtttgt tattcttttc cagaaagaaa     2700

atgaatttga ctggttcacc tgtgtactga gtattgataa actttgaatt tttttaattg     2760

ccttcaattg ggagagaaag ctttatattt gtaagaaata tatttgataa agtttcttaa     2820

agcaacacca aaaaaacaaa agaaaagcta agtgaatttt tgcacattct acacacagtg     2880

cctgtaaatc tcatttgtat tttcagtttg cccttaattt tttttgttag tgtttagaaa     2940

acaatgtttt aaacattctt cagtgttctg atttcttatt accccctttc ctcttgggct     3000

tttgaactgt atttgatgtt gctttgggat aatgtttata agtcaaacat aagatattgt     3060

acattgggca catatctcct cttgggctgc taataataaa ttaataacag gtaacctgga     3120

caaaccagga agcaccaaac cccttttcag tttgaactct tctttgccag gtgtgaggac     3180

ttctgcatct tacagtcagc acagaacaca ctgagacttg aatcaagtca gcaacagagc     3240

aaaataaagg ttagataagt ccttgtgtag caaatttcga gcataagaaa taaaatctaa     3300

ttaattctta gggtactcat ctgacttgaa ctctgttggt ttactgtgtt agtaaactgt     3360

gctttctatt atctatacat aaaacctgag cagcaactgt gtctttagag ctattgccac     3420

attagccttt gcactgtata gcgtctggct ttatggaact taagtttacc aaatataaaa     3480

agaaacttct gcttttaaaa aaattatata tatatattaa atttgaaacc tgcatttctc     3540

ccacagcaat gtaagaagta ggctctgatg tcctaccact ttgaatggtt ttctaatatc     3600

ttaatgaata gttcctgaac attgcactga tatcatcgat tagaattttg atatttaatt     3660

tcatctttat ttcctggtag agaatgcagg aaaagatgtc aggtacataa cataaaacag     3720

attgggaatt tattgtttcc aaagggcatg gccttcctta gcatcagttt gaagcttttg     3780

ttatgactta gctgacttgt ggcagcgggg caagcaaaaa caataacact gcttataaat     3840

ggcaccacat cttgttaacc tcccccccaa atactctctg aaagtcatgc acatacctat     3900

gggattttac acaccaccag cttaaaatgc tatgtctcta tccatcagaa atagtcatta     3960

ttctattttt aaggcagcaa caagaaaaga aaaaacactt ttcctgaggg atttctaacc     4020

atgtatctaa tcctcccatt tgggcagtat aggtgtttgc ttttttgttt tcttttttta     4080

agaaaaacct tgaaaccttt gacactgaca gatgtgtttg caaggatacg gcttcagtat     4140

tactaatttc catgtgtatc tggaagtatt tttaaatggc ataccaaaat ccagaagttt     4200

aaagatgcct ataaaagtaa acaacattta tttaaaaaga actctgaata tgccttcttt     4260

tttaattaga aatatcttcg agacttgggt gtttgttaat aactaataac tggagtaagc     4320

tacaggatct aaagcagccc tttttacagt ctagttagga gagagaaaat aattgcaaat     4380

atccacttag aggcaaagaa caatttttta ttatcaaaaa ggtttctgca cattgttgtg     4440

gcaatattgt atctgtttag aaaatgggct tttccaaaag caaacaaaga taggttcctc     4500

aggtgaccaa aactgaaaat caatatttcc atgtttcatt aatcaaggca taaaatacaa     4560

ttaaagcaaa atattttaca ttaaaaaaaa aaaaaa                               4596


<210>  1077
<211>  5569
<212>  DNA
<213>  homo sapiens

<400>  1077
agaacgagtt ccggtctggc cgaggcttgt ctcctaaaaa tagccccggt gtggggatcc       60

gtgcgcggat gtcccggcga gtcccgggct gaaagaggcg gctccgggcg gcgcgaagcg      120

ctggtggcgg gcccgggctg cggcgtgtgc gcgcccgcca gctgctccgg agatacggaa      180

ttgcattttg tgaaaaaaga acaagaattt tctgcaagga tcatatctaa gtgcactttt      240

tgctgatact tcatttctaa tcttgtagaa aatttcagct gtagcccttg gactagaagc      300

tgaaataaca gaagctgtgt acgatgcatt agggtattga agaaaattaa cttttgaatt      360

aaatatttgg aatataagga aataaggaaa gttgactgaa aatggggcgg aagaaaatac      420

aaatcacacg cataatggat gaaaggaacc gacaggtcac ttttacaaag agaaagtttg      480

gattaatgaa gaaagcctat gaacttagtg tgctctgtga ctgtgaaata gcactcatca      540

ttttcaacag ctctaacaaa ctgtttcaat atgctagcac tgatatggac aaagttcttc      600

tcaagtatac agaatataat gaacctcatg aaagcagaac caactcggat attgttgagg      660

ctctgaacaa gaaggaacac agagggtgcg acagcccaga ccctgatact tcatatgtgc      720

taactccaca tacagaagaa aaatataaaa aaattaatga ggaatttgat aatatgatgc      780

ggaatcataa aatcgcacct ggtctgccac ctcagaactt ttcaatgtct gtcacagttc      840

cagtgaccag ccccaatgct ttgtcctaca ctaacccagg gagttcactg gtgtccccat      900

ctttggcagc cagctcaacg ttaacagatt caagcatgct ctctccacct caaaccacat      960

tacatagaaa tgtgtctcct ggagctcctc agagaccacc aagtactggc aatgcaggtg     1020

ggatgttgag cactacagac ctcacagtgc caaatggagc tggaagcagt ccagtgggga     1080

atggatttgt aaactcaaga gcttctccaa atttgattgg agctactggt gcaaatagct     1140

taggcaaagt catgcctaca aagtctcccc ctccaccagg tggtggtaat cttggaatga     1200

acagtaggaa accagatctt cgagttgtca tccccccttc aagcaagggc atgatgcctc     1260

cactaaatac ccaaaggatc agtagttctc aagccactca acctcttgct accccagtcg     1320

tgtctgtgac aaccccaagc ttgcctccgc aaggacttgt gtactcagca atgccgactg     1380

cctacaacac tgattattca ctgaccagcg ctgacctgtc agcccttcaa ggcttcaact     1440

cgccaggaat gctgtcgctg ggacaggtgt cggcctggca gcagcaccac ctaggacaag     1500

cagccctcag ctctcttgtt gctggagggc agttatctca gggttccaat ttatccatta     1560

ataccaacca aaacatcagc atcaagtccg aaccgatttc acctcctcgg gatcgtatga     1620

ccccatcggg cttccagcag cagcagcagc agcagcagca gcagcagccg ccgccaccac     1680

cgcagcccca gccacaaccc ccgcagcccc agccccgaca ggaaatgggg cgctcccctg     1740

tggacagtct gagcagctct agtagctcct atgatggcag tgatcgggag gatccacggg     1800

gcgacttcca ttctccaatt gtgcttggcc gacccccaaa cactgaggac agagaaagcc     1860

cttctgtaaa gcgaatgagg atggacgcgt gggtgaccta aggcttccaa gctgatgttt     1920

gtacttttgt gttactgcag tgacctgccc tacatatcta aatcggtaaa taaggacatg     1980

agttaaatat atttatatgt acatacatat atatatccct ttacatatat atgtatgtgg     2040

gtgtgagtgt gtatgtgtgg gtgtgtgtta catacacaga atcaggcact tacctgcaaa     2100

ctccttgtag gtctgcagat gtgtgtccca tggcagacaa agcaccctgt aggcacagac     2160

aagtctggca cttccttgga ctacttgttt cgtaaagata accagttttt gcagagaaac     2220

gtgtacccat atataattct cccacactag cttgcagaaa cctagagggc cccctacttg     2280

ttttatttaa ctgtgcagtg actgtagtta cttaagagaa aatgctttgt agaacagagc     2340

agtagaaaag caggaaccaa gaaagcaata ctgtacataa aatgtcattt atattttcca     2400

acctggcatg ggtgtctgtt gcaaaggggt gcatgggaaa gggctgttga tattaaaaac     2460

aaacaaaaca aaaaagcccc acacataact gttttgcacg tgcaaaaatg tattgggtca     2520

agaagtgatc tttagctaat aaagaaagag aatagaaaac acgcatgaga tattcagaaa     2580

atactagcct agaaatatag agcattaaca aagtaaaatt aatatattaa gttataattg     2640

gaatatgtca gaagtttctt tttacattca tatcttaaaa attaaagaaa ctgattttag     2700

ctcatgtata ttttatatga aagaaaacac ccttatgaat tgatgactat atataaaatt     2760

atattcacta cttttgaaca cattctgcta tgaattattt atataagcca aagctatatg     2820

ttgtaacttt tttttagaga atagctttat cttggtttaa ctctttagtt ttattttaag     2880

aggggaaaac aaaaatatct tgcaagcaga accttggaaa aaaaaagcca tgaacactta     2940

ttctaaatgt aaattaaaag ttgagccaaa ctctttgtgt atatagcatc ttaaatatat     3000

tatcaccttt gatgtaagta cctatgtatt gtatggtcac cagattaaaa agtatatttt     3060

tgtggattgc cgccaatctg gggggaaaag gcgaggtcct ttattaagta ttcactgttt     3120

aatatttact attttgttaa atatactgta ctttggattt taattattag cccagttttt     3180

tcagaggatt gtataaaggg gtttctcccc tcactggtgg tgaatgtgtg atgttacatt     3240

gtaatctttg tgctgtatgg gttgagcatc attatatatt ttgtatgtgt acataaatag     3300

caaagtggca aaaaaaattg gtgttaagtt catcctgcat aagtataaaa tgtgttgtaa     3360

cagattttgt aaggcattat ttaaaacttg ccttttgtga ggaaaaaatg tagtagaaaa     3420

agctgaccta atttaattaa tattagagaa aatggcaaaa tagtagatga gcacaaaggt     3480

tttataagtg gtaaatgatt aggggaaaat aatcatgggg aaagggatct tttttccttg     3540

accctctgaa aacagaacga tgcagctggt tacaaaatcc taccgttatc agctcttctg     3600

cacattgcag tgatgctttg gtatgcgggg agaaacactc ttagggtgct ggtccttggc     3660

atgactcttg ccattctaat tggaattagt gccaccctca gcttggattt tgaacaaggc     3720

cttattcttt caggaagaca actaatggat gatagcaagt tcatccactt actgggcttg     3780

tgccatgagc aaaattcaaa gtcctgtata tctttcattg tagattttta aatactcctt     3840

ttcctaaaaa actcaagggt ttaaaaattg ctattttata ttttaaatga tattgagcag     3900

ctacctacaa tttctatgta cattttgttc cccccccccc accccccccc caaattacgt     3960

tccttttgac attttcctca tctgctgttt gtgacaagtc atcagccaga tttcctgact     4020

gacacatagg tatgatcagt gcaggagaga cctgcgcacc acaggctgca aactggaggt     4080

tctgttctca tggcagtttg ggcagtaact tttgagagag gccaaaaaaa ggaggatgac     4140

atgctgtctc ctctcttcag tatagacatt aggctcttat tcagaaagga tttttcttta     4200

aaaatgtact tactttactg aactacttac aggcacattt cttcataagg ccacacctaa     4260

tccaaacaag acagtctccc aacactgaag ttccaaaata atccttacca ctttgtaaac     4320

catttatagc tttgaaagtg ttaagtgatt ccttcgttat tatttatgca tgttcatgaa     4380

cttctgctgt acattggaat aggagttaac acattcacat ttactgtcta ttttcttgtg     4440

tgccttatga gatggctttt ctgactgtat ctcaatagtc tttctttcta tgcaggttta     4500

taatcagtac aactactgtt ttctaaaata ctactactca aggctcggag tttgtattta     4560

aattacactg accaagtaac aatgtattcc atttcaggaa ctgaatattt gactgttaac     4620

ctttttccca tacgtccagt gtggcatgga gcatatggac ttgacagaca tctctcaccc     4680

agacgcccac gtgtgaacac acccacatcc acatctctgg gtggaaacca gcctagagag     4740

gggacgacgc taatggtgtt gctttagaac cgtcttttct taccctttta gactcgtgtt     4800

ttgtatgaga caccattgca agaaaatttt atccctccag aagtatttta ttactaaaga     4860

acaaaagcaa aaaaagctta aattgcactg gttaaagtac agtttccaac agctgtcctt     4920

cctcagtact ctaatggcca ctccaccgcg agtggaagtc actgttgtgt gtacacaggt     4980

ggtcccaatc aaaactccat cttttgagcc caattatgtc cattttgtta tagactaaat     5040

caggggtttg ttctacaaga acaatacatg ttttaccctt tcctttaact agaaggataa     5100

ctagtaatgc atcaacataa tttctgtatt aaccatcatg cgcacaagaa atacatagta     5160

aataaggaag ctgaaaactc ctggcattgg atcttaagct agatgattag aatgtgaaaa     5220

agattttaca aatgtaaaac ttctatttct ctgtagaaac tttcttcact ttgctgtgca     5280

agaagacact gctttgctat atttaaaatg gcttttttaa aagagattta tgtatttggt     5340

aaatgtttgt agtcaacagt tcacacaaga agctgtacac ggtttgatca tgtaaaaccg     5400

tttggcggca caagctggac tttgttgcca tccttgagat gaacctttta agaaaaataa     5460

gttaatctca atttttccct gaatgtgttg tttttcttca ttatacaata aatataatag     5520

tgaacttttt atcaaatggt gaagacaatg ctaaaaaaaa aaaaaaaaa                 5569


<210>  1078
<211>  3610
<212>  DNA
<213>  homo sapiens

<400>  1078
gagaggctgt gggagaaggg agggaccaga ggagagagcg agagagggaa ccagacccca       60

gttcgccgac taagcagaag aaagatcaaa aaccggaaaa gaggagaaga gcaaacaggc      120

actttgagga acaatcccct ttaactccaa gccgacagcg gtctaggaat tcaagttcag      180

tgcctaccga agacaaaggc gccccgaggg agtggcggtg cgaccccagg gcgtgggccc      240

ggccgcggag cccacactgc ccggctgacc cggtggtctc ggaccatgtc tcccgcccca      300

agaccccccc gttgtctcct gctccccctg ctcacgctcg gcaccgcgct cgcctccctc      360

ggctcggccc aaagcagcag cttcagcccc gaagcctggc tacagcaata tggctacctg      420

cctcccgggg acctacgtac ccacacacag cgctcacccc agtcactctc agcggccatc      480

gctgccatgc agaagtttta cggcttgcaa gtaacaggca aagctgatgc agacaccatg      540

aaggccatga ggcgcccccg atgtggtgtt ccagacaagt ttggggctga gatcaaggcc      600

aatgttcgaa ggaagcgcta cgccatccag ggtctcaaat ggcaacataa tgaaatcact      660

ttctgcatcc agaattacac ccccaaggtg ggcgagtatg ccacatacga ggccattcgc      720

aaggcgttcc gcgtgtggga gagtgccaca ccactgcgct tccgcgaggt gccctatgcc      780

tacatccgtg agggccatga gaagcaggcc gacatcatga tcttctttgc cgagggcttc      840

catggcgaca gcacgccctt cgatggtgag ggcggcttcc tggcccatgc ctacttccca      900

ggccccaaca ttggaggaga cacccacttt gactctgccg agccttggac tgtcaggaat      960

gaggatctga atggaaatga catcttcctg gtggctgtgc acgagctggg ccatgccctg     1020

gggctcgagc attccagtga cccctcggcc atcatggcac ccttttacca gtggatggac     1080

acggagaatt ttgtgctgcc cgatgatgac cgccggggca tccagcaact ttatgggggt     1140

gagtcagggt tccccaccaa gatgccccct caacccagga ctacctcccg gccttctgtt     1200

cctgataaac ccaaaaaccc cacctatggg cccaacatct gtgacgggaa ctttgacacc     1260

gtggccatgc tccgagggga gatgtttgtc ttcaaggagc gctggttctg gcgggtgagg     1320

aataaccaag tgatggatgg atacccaatg cccattggcc agttctggcg gggcctgcct     1380

gcgtccatca acactgccta cgagaggaag gatggcaaat tcgtcttctt caaaggagac     1440

aagcattggg tgtttgatga ggcgtccctg gaacctggct accccaagca cattaaggag     1500

ctgggccgag ggctgcctac cgacaagatt gatgctgctc tcttctggat gcccaatgga     1560

aagacctact tcttccgtgg aaacaagtac taccgtttca acgaagagct cagggcagtg     1620

gatagcgagt accccaagaa catcaaagtc tgggaaggga tccctgagtc tcccagaggg     1680

tcattcatgg gcagcgatga agtcttcact tacttctaca aggggaacaa atactggaaa     1740

ttcaacaacc agaagctgaa ggtagaaccg ggctacccca agtcagccct gagggactgg     1800

atgggctgcc catcgggagg ccggccggat gaggggactg aggaggagac ggaggtgatc     1860

atcattgagg tggacgagga gggcggcggg gcggtgagcg cggctgccgt ggtgctgccc     1920

gtgctgctgc tgctcctggt gctggcggtg ggccttgcag tcttcttctt cagacgccat     1980

gggaccccca ggcgactgct ctactgccag cgttccctgc tggacaaggt ctgacgccca     2040

ccgccggccc gcccactcct accacaagga ctttgcctct gaaggccagt ggcagcaggt     2100

ggtggtgggt gggctgttcc catcgtcccg agccccctcc ccgcagcctc cttgcttctc     2160

tctgtcccct ggctggcctc cttcaccctg accgcctccc tccctcctgc cccggcattg     2220

catcttccct agataggtcc cctgagggct gagtgggagg gcggcccttt ccagcctctg     2280

cccctcaggg gaaccctgta gctttgtgtc tgtccagccc catctgaatg tgttgggggc     2340

tctgcacttg aaggcaggac cctcagacct cgctggtaaa ggtcaaatgg ggtcatctgc     2400

tccttttcca tcccctgaca taccttaacc tctgaactct gacctcagga ggctctgggc     2460

actccagccc tgaaagcccc aggtgtaccc aattggcagc ctctcactac tctttctggc     2520

taaaaggaat ctaatcttgt tgagggtaga gaccctgaga cagtgtgagg gggtggggac     2580

tgccaagcca ccctaagacc ttgggaggaa aactcagaga gggtcttcgt tgctcagtca     2640

gtcaagttcc tcggagatct gcctctgcct cacctacccc agggaacttc caaggaagga     2700

gcctgagcca ctggggacta agtgggcaga agaaaccctt ggcagccctg tgcctctcga     2760

atgttagcct tggatggggc tttcacagtt agaagagctg aaaccagggg tgcagctgtc     2820

aggtagggtg gggccggtgg gagaggcccg ggtcagagcc ctgggggtga gcctgaaggc     2880

cacagagaaa gaaccttgcc caaactcagg cagctggggc tgaggcccaa aggcagaaca     2940

gccagagggg gcaggagggg accaaaaagg aaaatgagga cgtgcagcag cattggaagg     3000

ctggggccgg gcaggccagg ccaagccaag cagggggcca cagggtgggc tgtggagctc     3060

tcaggaaggg ccctgaggaa ggcacacttg ctcctgttgg tccctgtcct tgctgcccag     3120

gcagcgtgga ggggaagggt agggcagcca gagaaaggag cagagaaggc acacaaacga     3180

ggaatgaggg gcttcacgag aggccacagg gcctggctgg ccacgctgtc ccggcctgct     3240

caccatctca gtgaggggca ggagctgggg ctcgcttagg ctgggtccac gcttccctgg     3300

tgccagcacc cctcaagcct gtctcaccag tggcctgccc tctcgctccc ccacccagcc     3360

cacccattga agtctccttg ggccaccaaa ggtggtggcc atggtaccgg ggacttggga     3420

gagtgagacc cagtggaggg agcaagagga gagggatgtc gggggggtgg ggcacggggt     3480

aggggaaatg gggtgaacgg tgctggcagt tcggctagat ttctgtcttg tttgtttttt     3540

tgttttgttt aatgtatatt tttattataa ttattatata tgaattccat tcaaaaaaaa     3600

aaaaaaaaaa                                                            3610


<210>  1079
<211>  7221
<212>  DNA
<213>  homo sapiens

<400>  1079
cactcgctct ctccctctgt gtatagagga tgtgctgaat ggtgcgcttt gaggcggcgg       60

cggcggagga gcagaatccg ccgcgactgg cagcctcggc tgaccggctc ggcttctctt      120

cgccttccga ggctcctcat ccaccgcggg ctccagacct cgcgtcccgc ccggggcatg      180

gccgggcgct gcgcccccgc gcgctctgcc tgctgagcgg cgccggaggg aggtgcggag      240

gccgggaggc cggggaggcc ggcggggagc agagtcgagc gcctccggag cagagaaagg      300

agcccgcgcc ccgcgccccg cgccccgcgc acggtcccca gtccctgccg cgctcgcccg      360

ggccgcccgg agcccagatg agcccagatg gccggggctc aacccggagt gcacgccttg      420

caactcaagc ccgtgtgcgt gtccgacagc ctcaagaagg gcaccaaatt cgtcaagtgg      480

gatgatgact caactattgt tactccaatt attttgagga ctgaccctca gggatttttc      540

ttttactgga cagatcaaaa caaggagaca gagctactgg atctcagcct tgtcaaagat      600

gccagatgtg ggagacacgc caaagctccc aaggacccca aattacgtga acttttggat      660

gtggggaaca tcgggcgcct ggagcagcgc atgatcacag tggtgtatgg gcctgacctc      720

gtgaacatct cccatttgaa tctcgtggct ttccaagaag aagtggccaa ggaatggaca      780

aatgaggttt tcagtttggc aacaaacctg ctggcccaaa acatgtccag ggatgcattt      840

ctggaaaaag cctatactaa acttaagctg caagtcactc cagaagggcg tattcctctc      900

aaaaacatat atcgcttgtt ttcagcagat cggaagcgag ttgaaactgc tttagaggct      960

tgtagtcttc catcttcaag gaatgattca atacctcaag aagatttcac tccagaagtg     1020

tacagagttt tcctcaacaa cctttgccct cgacctgaaa ttgataacat cttttcagaa     1080

tttggtgcaa aaagcaaacc atatcttacc gttgatcaga tgatggattt tatcaacctt     1140

aagcagcgag atcctcggct taatgaaata ctttatccac ctctaaaaca agagcaagtc     1200

caagtattga ttgagaagta tgaacccaac aacagcctcg ccagaaaagg acaaatatca     1260

gtggatgggt tcatgcgcta tctgagtgga gaagaaaacg gagtcgtttc acctgagaaa     1320

ctggatttga atgaagacat gtctcagccc ctttctcact atttcattaa ttcctcgcac     1380

aacacctacc tcacagctgg ccaactggct ggaaactcct ctgttgagat gtatcgccaa     1440

gtgctcctgt ctggttgtcg ctgtgtggag ctggactgct ggaagggacg gactgcagaa     1500

gaggaacctg tcatcaccca tggcttcacc atgacaactg aaatatcttt caaggaagtg     1560

atagaagcaa ttgcggagtg tgcatttaag acttcacctt ttccaattct cctttcgttt     1620

gagaaccatg tggattcccc aaagcagcaa gccaagatgg cggagtactg ccgactgatc     1680

tttggggatg cccttctcat ggagcccctg gaaaaatatc cactggaatc tggagttcct     1740

cttccaagcc ctatggattt aatgtataaa attttggtga aaaataagaa gaaatcacac     1800

aagtcatcag aaggaagcgg caaaaagaag ctctcagaac aagcctccaa cacctacagt     1860

gactcctcca gcatgttcga gccctcatcc ccaggagccg gagaagctga tacggaaagt     1920

gacgacgacg atgatgatga tgactgtaaa aaatcttcaa tggatgaggg gactgctgga     1980

agtgaggcta tggccacaga agaaatgtct aatctggtga actatattca gccagtcaag     2040

tttgagtcat ttgaaatttc aaaaaaaaga aataaaagtt ttgaaatgtc ttccttcgtg     2100

gaaaccaaag gacttgaaca actcaccaag tctccagtgg aatttgtaga atataacaaa     2160

atgcagctta gcaggatata tccaaaagga acacgtgtgg attcatccaa ctatatgcct     2220

cagctcttct ggaatgcagg ttgtcagatg gtggcactta atttccagac aatggacctg     2280

gctatgcaaa taaatatggg gatgtatgaa tacaacggga agagtggcta cagattgaag     2340

ccagagttca tgaggaggcc tgacaagcat tttgatccat ttactgaagg catcgtagat     2400

gggatagtgg caaacacttt gtctgttaag attatttcag gtcagtttct ttctgataag     2460

aaagttggga cttacgtgga agtagatatg tttggtttgc ctgtggatac aaggaggaag     2520

gcatttaaga ccaaaacatc ccaaggaaat gctgtgaatc ctgtctggga agaagaacct     2580

attgtgttca aaaaggtggt tcttcctact ctggcctgtt tgagaatagc agtttatgaa     2640

gaaggaggta aattcattgg ccaccgtatc ttgccagtgc aagccattcg gccaggctat     2700

cactatatct gtctaaggaa tgaaaggaac cagcctctga cgctgcctgc tgtctttgtc     2760

tacatagaag tgaaagacta tgtgccagac acatatgcag atgtcatcga agctttatca     2820

aacccaatcc gatatgtgaa cctgatggaa cagagagcta agcaattggc tgctttgaca     2880

ctggaagatg aagaagaagt aaagaaagag gctgatcctg gagaaacacc atcagaggct     2940

ccaagtgaag cgagaacgac tccagcagaa aatggggtga atcacactac aaccctgaca     3000

cccaagccac cctcccaggc tctccacagc cagccagctc caggttctgt aaaggcacct     3060

gccaaaacag aagatcttat tcagagtgtc ttaacagaag tggaagcaca gaccatcgaa     3120

gaactaaagc aacagaaatc gtttgtgaaa cttcaaaaga aacactacaa agaaatgaaa     3180

gacctggtta agagacacca caagaaaacc actgacctta tcaaagaaca cactaccaag     3240

tataatgaaa ttcagaatga ctacttgaga aggagagccg ctttggaaaa gtccgccaaa     3300

aaggacagta agaaaaaatc ggaacccagc agccctgatc atggttcatc aacgattgag     3360

caagacctcg ctgctctgga tgctgaaatg acccaaaagt taatagactt gaaggacaaa     3420

caacagcagc agctgcttaa tcttcggcaa gaacagtatt atagtgaaaa ataccagaag     3480

cgagaacata ttaaactgct tattcaaaag ttgacggatg tcgcagaaga gtgtcagaac     3540

aatcagttaa agaagctcaa agaaatctgt gagaaagaaa agaaagaatt aaagaagaaa     3600

atggataaaa agaggcagga gaagataaca gaagctaaat ccaaagacaa aagtcagatg     3660

gaagaggaga agacagagat gatccggtca tatatccagg aagtggtgca gtatatcaag     3720

aggctagaag aagcgcaaag taaacggcaa gaaaaactcg tagagaaaca caaggaaata     3780

cgtcagcaga tcctggatga aaagcccaag ggggaaggtt cctcctcatt cttgtcggaa     3840

acttgccatg aggatccctc tgtttccccc aactttactc cccccaaccc tcaagctctc     3900

aagtggtgac caccgtcctt ccggccagct gcaggtggag ctggagcaag aataccaaga     3960

caaattcaaa agactgcccc tcgagatttt ggaattcgtg caggaagcca tgaaaggaaa     4020

gatcagtgaa gacagcaatc acggttctgc ccctctctcc ctgtcctcag accctggaaa     4080

agtgaaccac aagactccct ccagtgagga gctgggagga gacatcccag gaaaagaatt     4140

tgatactcct ctgtgaatgc tcctgccagg ccttcagaaa ttgcatggcc actccagcgt     4200

catcggactc tctcttatta caaagatcac tgcccaggac catcttcccg agaagcatcc     4260

cttagcctaa aatccacacc aaagggagag ttccagagga atccatgaag aattcccatg     4320

cccaggctcc atgtgtcatg tggaaacctc cacaggtctg ctagtgaaga atgcatgtat     4380

gtgagatttt tgttttcttt ccaatagcaa attcaaagca agcaacttgc aggctccatg     4440

gaacttttaa tgaaggacag tgtcttcttt gaagaaaatc aagctcgtgt ttttattcga     4500

agctctggtg taaaatattt caaagtcata gaaatagttt gagaaatgca tagcattatt     4560

taacactatt gaacagccga ctttgagcat tgtttcttct aactgcccct caactaccat     4620

tatcttcaag tcaacatgca tattacattt tcatcctttg ctttgcaagc actggtggct     4680

tgcagtttgc taatttattt atcatagagt catcaatgta tttgttgctg acatggtttt     4740

attagatact gtagtgattc aaataagttt tctatttgaa aaaaaaaatc acttgattgt     4800

atccttgccc agtgaagcca tcctaagact tagcaatatg gattgtacat ttggctgcat     4860

gagcaagtcg gccgcacact tccagacagt gtgctgtttg aattgactat ttgcactcaa     4920

agtctgggta ttcattggtt attggcctga aatgatcaaa taactacaaa tgatctgttg     4980

aataaaaata gttgagctga tatatgttaa gcagatattc aatcagaatg aacaggttcc     5040

ggtggttatt ttgccgtttg acatttttta tggttcattt atttttaata tagagaggaa     5100

gattgaatat ttatctagag aatacaaaga cccacatgta aatgataggt attatctcca     5160

tgtatatatg tacccactta gtcatgtaag tgcatataca catacacaca catgagtgta     5220

gacatgtgtt tattaattga caatgaccca aatctcttcc acaagactta aaaccaaatt     5280

cagggacaaa tggatagaga agaaaagggt caaacatcga gattacatgg atgttaaatt     5340

atatggagac gctaagaaat aattgatgga gccattgatg caaaccgaag tagatttaga     5400

acttatatga atttgattta tattttgcaa gatcaaaaat tagatgttaa gtatcagatt     5460

ttaagcttgt tttaatggtc aaaaaattag gacagaaata atatggacat ttattagtat     5520

cttccataat ttttaagtct gacacatttc tattttattc taacataaaa aaacttccat     5580

tatatattta ctaagtatat ttaattcact taactctgtc tttataagtt cctattttag     5640

atggaataag agaaacaaat tatatcaagg taaaactgat caaaagcata attgaaagtt     5700

ctgaaaaaag aaaaataata atatgtagaa aaatgtaact tagagagtaa cacatgaaca     5760

ttgaagttaa aacccagaag ccagatgctc acagttttat tttactttaa aataaacctg     5820

tctgactgta gctttgtgaa atatcttaaa acgcaaaaac caattgtgtc ctgaaaattg     5880

tttcaagaat ttaatatttt tatgaaaatt attttattta actttaagca ataactagag     5940

attacaatta aattttaatc aaaatgaagg cttagttcaa acataaggaa acagtgtttg     6000

attaaaaaaa acacatctag taagacgtaa ggggaaaatc acatcctctt tggagatgat     6060

tatattttga tctgaagggt ttggggtgtt cattagacac ttaataaaac ttaacttcca     6120

atgaaaaaga aatcttttgt aaatcattct acttttgcac tttgaaagaa aggcgttaat     6180

cataaagaag caagaatggt caaaatcgaa tgctgcattt ttataaacaa aattacagac     6240

tgtctgaaat tgaagaagaa tgaactaata atagcattca taaccaaaca caatgatgat     6300

tattgcagaa cattgtatca cattttagtc cagagataga ataaagttga ataaccttga     6360

cttacacaaa actgttttgg tagttggatt tcattatctt agtgaattta gtcattttac     6420

aatatgtttg tatttggcca tttactgtaa tcacattttt atatctgtac aatgacactt     6480

tttgcagttg tggggtagtg tgtaacactg tccatcttgc atcattgaaa ctactacaat     6540

gatactatca tttaataata ttaatattac ttgaaataga ctaagataaa gaaaaggggt     6600

ctgtatgatg tgcagttttg tgcctttatg tatttgcctt gttctttgtc gaatgtgtga     6660

aattccgtac tgtggttttt cctataatag aaagtagagc tgtgtattaa attagactgt     6720

gtctctctga tacctttaca ctactgagaa tagcatggtt ttggccatgt aaaccaattt     6780

tcaaagttct aatgacatag ccatgtgttt ttggtttttt atatttcatt ttaaaatttg     6840

agtatcacca tacattaatt aatactcctg tagtagataa gctgtcatta agtaattccc     6900

aaaaaaaggg ccatttgctt gcattacttt gaatttaatg ttgcgcttgt gcactgtgtt     6960

aatattgttt gtgatggatt ggacgttgtg actcttgcct tttaagaaga aaaaaaagat     7020

aggacaaagt atttgaagct cttaaaatgt acatattttg gttcttctat ctcaaattat     7080

ttaaaatgca taattcacat ttttgtaata attctatgca attttgtggc atgatgtttc     7140

ttccacttgt aattttatgt gctttcatca caaatccaaa ggaaagaata aaaatttctt     7200

aacacaaaaa aaaaaaaaaa a                                               7221


<210>  1080
<211>  1439
<212>  DNA
<213>  homo sapiens

<400>  1080
tttctacttt gcccgcccac agatgtagtt ttctctgcgc gtgtgcgttt tccctcctcc       60

ccgccctcag ggtccacggc caccatggcg tattaggggc agcagtgcct gcggcagcat      120

tggcctttgc agcggcggca gcagcaccag gctctgcagc ggcaaccccc agcggcttaa      180

gccatggcgc ttctcacggc attcagcagc agcgttgctg taaccgacaa agacaccttc      240

gaattaagca cattcctcga ttccagcaaa gcaccgcaac atgaccgaaa tgagcttcct      300

gagcagcgag gtgttggtgg gggacttgat gtcccccttc gaccagtcgg gtttgggggc      360

tgaagaaagc ctaggtctct tagatgatta cctggaggtg gccaagcact tcaaacctca      420

tgggttctcc agcgacaagg ctaaggcggg ctcctccgaa tggctggctg tggatgggtt      480

ggtcagtccc tccaacaaca gcaaggagga tgccttctcc gggacagatt ggatgttgga      540

gaaaatggat ttgaaggagt tcgacttgga tgccctgttg ggtatagatg acctggaaac      600

catgccagat gaccttctga ccacgttgga tgacacttgt gatctctttg cccccctagt      660

ccaggagact aataagcagc ccccccagac ggtgaaccca attggccatc tcccagaaag      720

tttaacaaaa cccgaccagg ttgccccctt caccttctta caacctcttc ccctttcccc      780

aggggtcctg tcctccactc cagatcattc ctttagttta gagctgggca gtgaagtgga      840

tatcactgaa ggagatagga agccagacta cactgcttac gttgccatga tccctcagtg      900

cataaaggag gaagacaccc cttcagataa tgatagtggc atctgtatga gcccagagtc      960

ctatctgggg tctcctcagc acagcccctc taccaggggc tctccaaata ggagcctccc     1020

atctccaggt gttctctgtg ggtctgcccg tcccaaacct tacgatcctc ctggagagaa     1080

gatggtagca gcaaaagtaa agggtgagaa actggataag aagctgaaaa aaatggagca     1140

aaacaagaca gcagccacta ggtaccgcca gaagaagagg gcggagcagg aggctcttac     1200

tggtgagtgc aaagagctgg aaaagaagaa cgaggctcta aaagagaggg cggattccct     1260

ggccaaggag atccagtacc tgaaagattt gatagaagag gtccgcaagg caagggggaa     1320

gaaaagggtc ccctagttga ggatagtcag gagcgtcaat gtgcttgtac atagagtgct     1380

gtagctgtgt gttccaataa attattttgt agggaaagta aaaaaaaaaa aaaaaaaaa      1439


<210>  1081
<211>  1409
<212>  DNA
<213>  homo sapiens

<400>  1081
atgcacacat acgcgcgcgc acatgcacat aggcacacag agatacgcgc acacacacac       60

acaaacgcac tcagatttcc cggaccctgg ttttcctcct gtgacccttt cggggccggg      120

ctctcaccct aaagaagcag ccccgccctg gggtggcccc accctctctt gggacctgtc      180

ataagtcgga ccccgggcgc ccggctgcgc agtcccagcc gccttcccca ggcagtggaa      240

ccttcgggct cctgagcttc aggatggttc gtactaagac atggaccctg aagaagcact      300

ttgttggcta tcctactaat agtgactttg agttgaagac agctgagctc ccacccttaa      360

aaaatggaga ggtcctgctt gaagctttgt tcctcaccgt ggatccctac atgagagtgg      420

cagccaaaag attgaaggaa ggtgatacaa tgatggggca gcaagtggcc aaagttgtgg      480

aaagtaaaaa tgtagcccta ccaaaaggaa ctattgtact ggcttctcca ggctggacaa      540

cgcactccat ttctgatggg aaagatctgg aaaagctgct gacagagtgg ccagacacaa      600

taccactgtc tttggctctg gggacagttg gcatgccagg cctgactgcc tactttggcc      660

tacttgaaat ctgtggtgtg aagggtggag aaacagtgat ggttaatgca gcagctggag      720

ctgtgggctc agtcgtgggg cagattgcaa agctcaaggg ctgcaaagtt gttggagcag      780

tagggtctga tgaaaaggtt gcctaccttc aaaagcttgg atttgatgtc gtctttaact      840

acaagacggt agagtctttg gaagaaacct tgaagaaagc gtctcctgat ggttatgatt      900

gttattttga taatgtaggt ggagagtttt caaacactgt tatcggccag atgaagaaat      960

ttggaaggat tgccatatgt ggagccatct ctacatataa cagaaccggc ccacttcccc     1020

caggcccacc cccagagatt gttatctatc aggagcttcg catggaagct tttgtcgtct     1080

accgctggca aggagatgcc cgccaaaaag ctctgaagga cttgctgaaa tgggtcttag     1140

agggtaaaat ccagtacaag gaatatatca ttgaaggatt tgaaaacatg ccagctgcat     1200

ttatgggaat gctgaaagga gataatttgg ggaagacaat agtgaaagca tgaaaaagag     1260

gacacatgga atctggaggc catttagatg attagttaat ttgtttttca ccatttagca     1320

aaaatgtata ctaccttaaa tgtcttaaga aatagtactc ataatgagtt tgagctactt     1380

aataaaatac atttaagtgg tatgtaaaa                                       1409


<210>  1082
<211>  6839
<212>  DNA
<213>  homo sapiens

<400>  1082
cggcagctgt cccgcctgcc acaatgcgcg gcgaagctgc ggccgcgact tggcgaggtg       60

gtccctaacg ttgccgctcg gcatccttag aaccggccgc ccctgacgcc gcgcggggac      120

cccagtcgcc cgcgcgcccc atgcgctcac tcttcggtgc ccggccgggc cggcgcctcg      180

cagacgcgga gccgcgcggg tgacggcaca ggcggctgcg cgcccagccc agcccagccc      240

agcccgagga gagggcgcgc cgcgcccccg ccccccgccc gctctcccga ggccgtgggt      300

gcggatgcgc ggctgacgac tcgcagcaag agcaccgccg ccggccccag cccgcagcat      360

ggcagccgcc gcctatgtgg accacttcgc cgccgagtgc ctcgtgtcca tgtcgagccg      420

cgcggtcgtg cacgggccgc gggaggggcc ggagtcccgg cccgagggcg cggccgtggc      480

cgccaccccc acgctgcccc gcgtcgagga gcgccgcgac ggtaaggaca gcgcctcgct      540

cttcgtggtg gcgcggatcc tagcggacct caaccagcaa gcgccggcgc ccgccccggc      600

ggagcgcagg gagggcgccg cggcccggaa ggcgaggacc ccctgccgcc tgccgccgcc      660

cgcccccgag cccacctccc ccggcgccga aggcgcggcg gccgcgcccc ccagcccggc      720

gtggagcgag ccggagcccg aggcggggct ggagcccgag cgggagccgg ggcccgcggg      780

gagcggcgag cccggcctca gacaaagggt ccggcggggc cgaagtcgcg ccgacctcga      840

gtccccgcag aggaagcaca agtgccacta cgcgggctgc gagaaagttt acgggaaatc      900

ttcgcacctc aaggcgcacc tgagaactca cacaggtgag aggcccttcg cctgcagctg      960

gcaggactgc aacaagaagt tcgcgcgctc cgacgagctg gcgcggcact accgcacaca     1020

cacgggcgag aagaagttca gctgccccat ctgcgagaag cgcttcatgc gcagcgacca     1080

cctgaccaag cacgcgcgcc gccacgccaa cttccacccg ggaatgctgc agcggcgcgg     1140

cgggggctcg cggaccggct ccctcagcga ctacagccgc tccgacgcca gcagccccac     1200

catcagcccg gccagctcgc cctgagcccg ccacagccat gagcagccgc tcccaccccc     1260

tcgtgagtcc ctggcctttc cttttgtaat aagaaagaag agagagaact tgatgcaaag     1320

tccacgaaaa aacaattttt ttcacctcag gtgtcaaagt aaatttgtta aaaaaacaaa     1380

aaaaacacaa aaatttcaaa aaacaccacc caccaaattg cacaatagat acacccacaa     1440

agttgagatt cagcgttgtt gaaccccctt tctcagggat ggacacgttt cacgaggtca     1500

gtgaggacac cccttcctgc cgccttactc tgtacataga tttgcactct ggagttttct     1560

gttaggttcg ggaacacgct ggggacagag caggccagcc agtctggtgg agctcagcgt     1620

ctggctggct ggccagcctg tgggtctgtt gggagcagat gtgctcactg acgtttgtgc     1680

ctccagggca gattcctaag cagctggcct gacctcttcc tgcccagccc ccaacccagt     1740

ctctggcctc tgcccaacga gcctggctgg gcttgcaacg cagctgattc tgagacaggc     1800

ccctgcagag ggatgcctta aagctgtccc tggctggagg agcactccac cttggggata     1860

gtggaggggg ccttcagccc tctgcaccct gcctgcctca caccccgcct tcaggagccc     1920

tctcctacgg cgctagggag cactggaagc agagatgcca gccctggctg agcgtagcac     1980

tgcaccgtcc gacctccgag gcaggggccg gggtcacacc tgccaggact ccgcttctcc     2040

gtgtcccagc agaaggcatg caggaccctg tcactactat acctgggcct ctgatgggga     2100

attctggtct tctaaaaaga tgttagaaat tcctggtggc acatccagtt ccgagtttgc     2160

ccgcacgggc acttttgttg gaaacagtgg gcaggtcatg gggcctcctc atcagagggt     2220

ctgtgtgagc ggctgtgcat gtggcagcgc accatgcttc acagagacca ttctgtagca     2280

agagaccgga acattgtgac ttggaccttt tcaggagtgg cgcggatgtt acaggaaatg     2340

ctgtcggaga gcgcgcattc tatttcctcc gcagggaatg ccagatagaa agttgcgggc     2400

aacacttttc tcagacccac catgtcccca actcagactt agcaaacctc cagcctctcc     2460

gtttcccctg gactcctcct cccttttcct cctgcttctc cttgtcctgc ctggaggctc     2520

caggccacac ccagctggtg gggctgctcc agtgccccat caccggcctt ctcctggcag     2580

gagaggagga gcagagagct gggtcctggg ctgggattcg agccctgggc gggggtcagt     2640

caagccgtgg tccagcaaac tcctctgcag atggctggag tgttgaccca ggcttgtggc     2700

ccaggtatca ccttcccttc ctcctgagag ttgaggcctg taaatacaag ggcccaggac     2760

agagtgtgtg cgtgcgtgtg ggtgtgtgcg cgcgtgagca cacacgcgtg tgttgggggg     2820

ggtgggggga ttggggtgga ctcagggtat cttgccagag atacctgttt tgatgagtac     2880

ctattttgat gcaaaggaac ggccctggga cctcagaggg ccacagatgg gcttcctggg     2940

cctagcgtgc cttggttgtg gccatcctgc ttctactcag ccctgccatg ctatggggtg     3000

cagcacaaac ccaggaccca ggcctagcca ctgcccacag ctgatggtca ctgttttggc     3060

tggctccaga gtggacaggt acgctctgtc cacagcagct gctcaggcac agtatgccgt     3120

caggtgcccg cttcttacca ctgtgtgtca gctgggattg gccgacagcg tggtggtgac     3180

ttctaggtag accgatggac cctaaattgg gcagtggcat tgtttctgct gtggtgggaa     3240

ctggcaggga gagggtcacc tccactctgg ttggatgcgg agctggtccc tctggctgcc     3300

atgctgtgtt ggggctctct gacctccctg cttgcattgg gtctgggaga gagagtggaa     3360

tatttggtag ggaccttgac agaagagagc cctgggtgct tgtggtgcaa agatcttcat     3420

gcccagttcc aaagtgaggt ccctcccaaa gttgttttcg tgtgaggcag agaaagccac     3480

actctgaata cattttatgt ctcaggaatt cacattccag gttcaggaat tttattccaa     3540

agtcctttgg tgcactcacc gtccaccgtt ccccaaggca gggagaggga gtggcccgtc     3600

cctgggaggc tggcaaagtg ctctccaggg aggggtcaga cgtccttgtg atctgcccag     3660

ggtgtcacgg aaggagattt tctagctcca catctgtctg cacataggaa ggaaaagata     3720

ggactctaaa cctagtcatc ttggaataaa aagaagagct ggtttgtttt agagcagggc     3780

ggggggtggg ggagggaagc gggtgttggc tgtttccaaa gagagcactt aatttaattt     3840

ttcctttaaa tgacccaggg ctgttccgtc tgatagatgg aagggtaaca ttgccttaaa     3900

acagaaatat gcaggcgttg gctatttttg gcataagagc gtgtcttcat tcccaaagtg     3960

gttctcgttt aatggcaggg tgcggtcctt aggccccggc ctggactggg aaatgggggt     4020

agggcaccag gagagaaatc ctcctgggta ctcctggcca gaccctcctg aatcatctgc     4080

ggcttaaact catctcgctt gaagggcagg gagaaaccca tgaatctcag gcacggttca     4140

caggggtcct caagggcagg tttccatttc atcatgaagt gagggactcc tgtggaagag     4200

ggtggtgggc cttggaacgc tgcctccact gaggcgggca cacaaggcgg accctcctga     4260

aacagcctcc attttcttca aacatgcaga atgttttccc agactgcgtc tatttcaggg     4320

tcttccattt ttgtggttta tggccatgct tgccagtttt ggtggggttg aggaacccat     4380

aggactcata gaaataatag tgaaaactca aacccttatt ttgggacttc agttctcgtg     4440

gtccataggg gcagagatgt caaagtgaag gttgcctgag tgaagggaga gttcccctat     4500

aaaaggccta aaattgatct ggggctcagc catcaagggg ctggtgttgc tcctgtccca     4560

gacaaggaag cccctcttta catcagccat attaggggaa cggttgtcag ctccccaaat     4620

gcctactgga tcctacagcc atacaggaaa acagacggac acagcccttt ccttaaagag     4680

ccctggggtc ctgtcctgca ggatgctgca taggaatggg cagagatgtc ctggatggga     4740

acatggtcct ggaggtgccc tacctgcatc ctgctgcacc cccacccacg acactcgagt     4800

gcaagatcgc ctcactccta accctgactt tattcccagg ccccacaccg aggcaggtgc     4860

aggattcgcc atggtgcagc ctccgggtac aaacatctga ggcactggcg atcccagtcc     4920

ttgcagcacc ctgaacacag ctcagaccag tgaggggtga ttcagaggtg gggatgggca     4980

gagagggctg gccactctgc ctcaggactt gacctcaagt gttctgtctc cccacccggt     5040

gtgtccagaa gaccagcctc tttcttgcca gaagcaggtg ctaagatgga ctgcacaggg     5100

tcccggcact ccctcgggac ccattcagga tctcagctgg gcaggggtgc cacccaacag     5160

gaagatgtga tctgagcaat agtgtggcct tgtttctccg cttctggttg tggctgtgtg     5220

tacagggcta cctattttga cttctgacag gtgtcactga ttttctttcc cccatttaaa     5280

aaaggtcatt tagtcaaaga cacagtgcta gaggtttaaa gggtgtaatg tgttggtcac     5340

atcacaacca gtaagaaacg cttggtaggt tatccacatc ttttgctgac tgtttccata     5400

tacaattctg gtcaccatat tttccaaagc taaaatctga ggcgtgggct gatggttttt     5460

gaaatcagga ttaccccagg aagaaccagg tcctattact aattttcctg attctgaggc     5520

tctgaaggct tgtctgagac acattccgga gacctttgta ccagaacttg gatgcatagt     5580

ccaccttact actgatacac gcctgagcac cctttagggc gaggcgccgc ctcctgcctg     5640

ctgtcctgtc cctcagcatc agaagagttg aattcagcag gagacgggag cccggtgtcc     5700

atgagggaag aggggtcgcg cttggtttct actgaccccc atgaagattt cagacttgca     5760

gtgcggccac ctggccctgc cctgcctctc tctttctcat acagctttaa aactttacta     5820

cttttattta aaaatgaact ggatgggaga gaagtagcgt cccctaccct acaagtcaca     5880

cattccgggg aggggggtgg ggggtggagg caggaagtca tgggggtggg ggtgggagca     5940

cgggaacagc tttcttaagg cctcagggtc ctgttttccc tggcctcttc tagagggccc     6000

gtggacaggt cgcagtgcgt gcttatttgg aaaccaggtg tgtgagccga atgcctgcca     6060

ggccatgcac tcagcagagg agcccttgta cctggctgcc ctgagaggag caagaggcca     6120

cctcccatgt ggctctagac accacgtggg ctcattagcc ccagcgtctg tgccggctcc     6180

aggtgcctgc ctctgggtgt gtgagtggga gactttgctc cctggcctca tcctagagag     6240

gcccctggtg cctagtgctg aggcctctgg ggctggaaag cctcagcaga aaggaggcac     6300

tactgagcaa ctatgcattg tcattgtcgg gtttggggct ttcggtggtt ccttggtgac     6360

tgggaattgc ttgtgtgcat gtgttgggtg catgcttccg ggtctcagct gccccaggcc     6420

cgcacaggca accccttccc atccaaagcc attggtggag cttctctgga atcatttgcc     6480

aaaagcccaa ggcagaatcc aagggtccaa gaccatttcc atggagctca tgtttttctt     6540

ttctgtagga actttttttt aaccagcacc caccataatt ccgaaggcca cgtttcatct     6600

ttcctggatc actacagtga agtattacag ttgtacagtt cccagtctgg ccttggcttg     6660

ctcggataaa actttgtatg tattttgtat ggcatagatt ctatattgta atgatgtcct     6720

atgcaaaaag aaaaattaac gaaattgtaa attttattgt tttaacgtgt atgcatgttt     6780

agtgacgttt acattttgaa ataaaattta tgattcatta ttttaaaaaa aaaaaaaaa      6839


<210>  1083
<211>  1503
<212>  DNA
<213>  homo sapiens

<400>  1083
gtgcagctgc tggcctcgta gacaatcggc tgtctcccca gaagagggaa agaattgtgc       60

agatgagaaa gaggctctca gcgggaggga ggcaggcggg cttgattgac acaggagagg      120

gctggctttt tggagggctc ttagcaacgg ccctggttga gccccctcag ccatgagaaa      180

atcaaatcaa tgtgccattc ttccaggcgc gaggcagcag cggctgcagt tcaacatgaa      240

aggaggcttc ctccctgcct gctaattacc tgctcttccc gatctcatcg tttctgcctt      300

tgcaaagtgc tactgagaag ggggaagaaa cgtccgccac ccatccccct tgctgcctgg      360

gggttcagac ttgattgtga aaccccattg gcttcattgg ctccttgatt taaaccacgc      420

ccggctttct gccctctttg ctgctgctgg gccaggttgc ccagccatat cccagccccg      480

tctgcaggga gccggaggct gctgctgctg ctattgtgtg gatgccgcgc gtgtcttctc      540

ttctttccag agatggctaa caggggcccg agctatggct taagccgaga ggtgcaggag      600

aagatcgagc agaagtatga tgcggacctg gagaacaagc tggtggactg gatcatcctg      660

cagtgcgccg aggacataga gcacccgccc cccggcaggg cccattttca gaaatggtta      720

atggacggga cggtcctgtg caagctgata aatagtttat acccaccagg acaagagccc      780

atacccaaga tctcagagtc aaagatggct tttaagcaga tggagcaaat ctcccagttc      840

ctaaaagctg cggagaccta tggtgtcaga accaccgaca tctttcagac ggtggatcta      900

tgggaaggga aggacatggc agctgtgcag aggaccctga tggctttagg cagcgttgca      960

gtcaccaagg atgatggctg ctatcgggga gagccatcct ggtttcacag gaaagcccag     1020

cagaatcgga gaggcttttc cgaggagcag cttcgccagg gacagaacgt aataggcctg     1080

cagatgggca gcaacaaggg agcctcccag gcgggcatga cagggtacgg gatgcccagg     1140

cagatcatgt aggacgcggc atcctgcccc tggtagagag gacgaatgtt ccacaccatg     1200

gtctctacga aaaagaaata gttagtcacc ttctgacctt ctcctctttc tcaaagcctt     1260

ctgtccctgg tttttgcaag tgctgcattt ccgccgagaa tccgcgttgc ctactgctgc     1320

cacctcctgt tcatttagaa ctatgcaaag actccgcttc cgttttcctg agctcctcgg     1380

gccccagagt ctctgtttga ttatttattt atttatttat ttatttgcca aaaattctcc     1440

tcttcaactt atagaatgca cctaataaag taattagtct tgtgtcttaa aaaaaaaaaa     1500

aaa                                                                   1503


<210>  1084
<211>  1795
<212>  DNA
<213>  homo sapiens

<400>  1084
gacttttcgc ctctcgctgg cctctaccga gcgcgtctat gagcgcagcg ttcccgccgt       60

cgctgatgat gatgcagcgc ccgctgggga gtagcaccgc cttcagcata gactcgctga      120

tcggcagccc gccgcagccc agccccggcc atttcgtcta caccggctac cccatgttca      180

tgccctaccg gccggtagtg ctgccgccgc cgccgccgcc gccgcccgcg ctgccccagg      240

ccgcgctgca gccagcgctg ccgcccgcac accctcacca ccagatcccc agcctgccca      300

caggcttctg ctccagcctg gcgcagggca tggcgctcac ctctacgctc atggccacgc      360

tccccggcgg cttctccgcg tcgccccagc accaggaggc ggcagcggcc cgcaagttcg      420

cgccgcagcc gctgcccggc ggcggtaact tcgacaaggc ggaggcgctg caggctgacg      480

cggaggacgg caaaggcttc ctggccaaag agggctcgct gctcgccttc tccgcggccg      540

agacggtgca ggcttcgctc gtcggggctg tccgagggca agggaaagac gagtcaaagg      600

tggaagacga cccgaagggc aaggaggaga gcttctcgct ggagagcgat gtggactaca      660

gctcggatga caatctgact ggccaggcag ctcacaagga ggaagacccg ggccacgcgc      720

tggaggagac cccgccgagc agcggcgccg cgggcagcac cacgtctacg ggcaagaacc      780

ggcggcggcg gactgccttc accagcgagc agctgctgga gctagagaag gagttccact      840

gcaaaaagta cctctccttg accgagcgct cgcagatcgc ccacgccctc aaactcagcg      900

aggtgcaggt gaaaatctgg ttccagaacc gacgggccaa gtggaaacgg gtgaaggcag      960

gcaatgccaa ttccaagaca ggggagccct cccggaaccc taagatcgtc gtccccatcc     1020

ctgtccacgt cagcaggttc gctatcagaa gtcagcatca gcagctagaa caggcccggc     1080

cctgagggtc cagaagggcc agggcctggc acccacctgg agaagccccc gcacccgagg     1140

gaacccatgg tggactccac tgtgtttgaa gcaacaaagt cacagcccag ctgtggccat     1200

cccaagcaaa ttgagaatat attcactaaa tgggcttaaa agactgcttt tgaaggggct     1260

tacagccaca ccagaagaca cgctaaatat ttattatact atcctacttt gtacataaat     1320

atctctatag actggatctc agctgcagta ttttgaaagt tataggactt aattacccag     1380

taatttctcc actcattcca gaagaaaaca aaacctctgc tgtaatctgc gcggttagca     1440

gccacctttc catacttttc caaaggtaaa cgtgaaaccc aagaacaagc actggggttt     1500

aaactgattt tggtttgcgt tctggctttt tgagttgact gaaaagcaga cattgttagg     1560

cagcctggaa attcgctttg ctttgctttg cttttgcctg gctttggttt cccctggggt     1620

tgcctatcct atctgagcca tgtgaagcac gtctccgttg tgttaattta tttcaatgta     1680

gcttattttc ttataagtta tgacatttaa acaatttcag tcttgtgaat aataaaaagg     1740

agagaggggg ggaaaaagac caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa          1795


<210>  1085
<211>  1220
<212>  DNA
<213>  homo sapiens

<400>  1085
agtcccagct cagagccgca acctgcacag ccatgcccgg gcaagaactc aggacggtga       60

atggctctca gatgctcctg gtgttgctgg tgctctcgtg gctgccgcat gggggcgccc      120

tgtctctggc cgaggcgagc cgcgcaagtt tcccgggacc ctcagagttg cactccgaag      180

actccagatt ccgagagttg cggaaacgct acgaggacct gctaaccagg ctgcgggcca      240

accagagctg ggaagattcg aacaccgacc tcgtcccggc ccctgcagtc cggatactca      300

cgccagaagt gcggctggga tccggcggcc acctgcacct gcgtatctct cgggccgccc      360

ttcccgaggg gctccccgag gcctcccgcc ttcaccgggc tctgttccgg ctgtccccga      420

cggcgtcaag gtcgtgggac gtgacacgac cgctgcggcg tcagctcagc cttgcaagac      480

cccaggcgcc cgcgctgcac ctgcgactgt cgccgccgcc gtcgcagtcg gaccaactgc      540

tggcagaatc ttcgtccgca cggccccagc tggagttgca cttgcggccg caagccgcca      600

gggggcgccg cagagcgcgt gcgcgcaacg gggaccactg tccgctcggg cccgggcgtt      660

gctgccgtct gcacacggtc cgcgcgtcgc tggaagacct gggctgggcc gattgggtgc      720

tgtcgccacg ggaggtgcaa gtgaccatgt gcatcggcgc gtgcccgagc cagttccggg      780

cggcaaacat gcacgcgcag atcaagacga gcctgcaccg cctgaagccc gacacggtgc      840

cagcgccctg ctgcgtgccc gccagctaca atcccatggt gctcattcaa aagaccgaca      900

ccggggtgtc gctccagacc tatgatgact tgttagccaa agactgccac tgcatatgag      960

cagtcctggt ccttccactg tgcacctgcg cggaggacgc gacctcagtt gtcctgccct     1020

gtggaatggg ctcaaggttc ctgagacacc cgattcctgc ccaaacagct gtatttatat     1080

aagtctgtta tttattatta atttattggg gtgaccttct tggggactcg ggggctggtc     1140

tgatggaact gtgtatttat ttaaaactct ggtgataaaa ataaagctgt ctgaactgtt     1200

aaaaaaaaaa aaaaaaaaaa                                                 1220


<210>  1086
<211>  1220
<212>  DNA
<213>  homo sapiens

<400>  1086
agtcccagct cagagccgca acctgcacag ccatgcccgg gcaagaactc aggacggtga       60

atggctctca gatgctcctg gtgttgctgg tgctctcgtg gctgccgcat gggggcgccc      120

tgtctctggc cgaggcgagc cgcgcaagtt tcccgggacc ctcagagttg cactccgaag      180

actccagatt ccgagagttg cggaaacgct acgaggacct gctaaccagg ctgcgggcca      240

accagagctg ggaagattcg aacaccgacc tcgtcccggc ccctgcagtc cggatactca      300

cgccagaagt gcggctggga tccggcggcc acctgcacct gcgtatctct cgggccgccc      360

ttcccgaggg gctccccgag gcctcccgcc ttcaccgggc tctgttccgg ctgtccccga      420

cggcgtcaag gtcgtgggac gtgacacgac cgctgcggcg tcagctcagc cttgcaagac      480

cccaggcgcc cgcgctgcac ctgcgactgt cgccgccgcc gtcgcagtcg gaccaactgc      540

tggcagaatc ttcgtccgca cggccccagc tggagttgca cttgcggccg caagccgcca      600

gggggcgccg cagagcgcgt gcgcgcaacg gggaccactg tccgctcggg cccgggcgtt      660

gctgccgtct gcacacggtc cgcgcgtcgc tggaagacct gggctgggcc gattgggtgc      720

tgtcgccacg ggaggtgcaa gtgaccatgt gcatcggcgc gtgcccgagc cagttccggg      780

cggcaaacat gcacgcgcag atcaagacga gcctgcaccg cctgaagccc gacacggtgc      840

cagcgccctg ctgcgtgccc gccagctaca atcccatggt gctcattcaa aagaccgaca      900

ccggggtgtc gctccagacc tatgatgact tgttagccaa agactgccac tgcatatgag      960

cagtcctggt ccttccactg tgcacctgcg cggaggacgc gacctcagtt gtcctgccct     1020

gtggaatggg ctcaaggttc ctgagacacc cgattcctgc ccaaacagct gtatttatat     1080

aagtctgtta tttattatta atttattggg gtgaccttct tggggactcg ggggctggtc     1140

tgatggaact gtgtatttat ttaaaactct ggtgataaaa ataaagctgt ctgaactgtt     1200

aaaaaaaaaa aaaaaaaaaa                                                 1220


<210>  1087
<211>  8957
<212>  DNA
<213>  homo sapiens

<400>  1087
ccttggggtt agttttagtc atatttttat ctctataaaa catcaggctg ggaggtggtg       60

tgtgcctgta gtctcaactg ctagggagcc tgaggcagga agactccttg agcacaggag      120

ttcaaggcca gcctgtgcaa catagtgaga ccctatcact ctggaaaaaa aaaaaaaatc      180

tgcggagaag aatgtcttcc aagcaagcca cctctccatt tgcctgtgca gctgatggag      240

aggatgcaat gacccaggat ttaacctcaa gggaaaagga agagggcagt gatcaacatg      300

tggcctccca tctgcctctg caccccataa tgcacaacaa acctcactct gaggagctac      360

caacacttgt cagtaccatt caacaagatg ctgactggga cagcgttctg tcatctcagc      420

aaagaatgga atcagagaat aataagttat gttccctata ttccttccga aatacctcta      480

cctcaccaca taagcctgac gaagggagtc gggaccgtga gataatgacc agtgttactt      540

ttggaacccc agagcgccgc aaagggagtc ttgccgatgt ggtggacaca ctgaaacaga      600

agaagcttga ggaaatgact cggactgaac aagaggattc ctcctgcatg gaaaaactac      660

tttcaaaaga ttggaaggaa aaaatggaaa gactaaatac cagtgaactt cttggagaaa      720

ttaaaggtac acctgagagc ctggcagaaa aagaacggca gctctccacc atgattaccc      780

agctgatcag tttacgggag cagctactgg cagcgcatga tgaacagaaa aaactggcag      840

cgtcacaaat tgagaaacaa cggcagcaaa tggaccttgc tcgccaacag caagaacaga      900

ttgcgagaca acagcagcaa cttctgcaac agcagcacaa aattaatctc ctgcagcaac      960

agatccaggt tcagggtcac atgcctccgc tcatgatccc aatttttcca catgaccagc     1020

ggactctggc agcagctgct gctgcccaac agggattcct cttcccccct ggaataacat     1080

acaaaccagg tgataactac cccgtacagt tcattccatc aacaatggca gctgctgctg     1140

cttctggact cagcccttta cagctccagc agctctatgc cgctcagctg gccagcatgc     1200

aggtgtcacc tggagcaaag atgccatcaa ctccacagcc accaaacaca gcagggacgg     1260

tctcacctac tgggataaaa aatgaaaaga gagggaccag ccctgtaact caagttaagg     1320

atgaagcagc agcacagcct ctgaatctct catcccgacc caagacagca gagcctgtaa     1380

agtccccaac gtctcccacc cagaacctct tcccagccag caaaaccagc cctgtcaatc     1440

tgccaaacaa aagcagcatc cctagcccca ttggaggaag cctgggaaga ggatcctctt     1500

taggtaaatg gaaaagtcaa caccaggaag agacttacga attagatatc ctatctagtc     1560

tcaactcccc tgcccttttt ggggatcagg atacagtgat gaaagccatt caggaggcgc     1620

ggaagatgcg agagcagatc cagcgggagc aacagcagca acagccacat ggtgttgacg     1680

ggaaactgtc ctccataaat aatatggggc tgaacagctg caggaatgaa aaggaaagaa     1740

cgcgctttga gaatttgggg ccccagttaa cgggaaagtc aaatgaagat ggaaaactgg     1800

gcccaggtgt catcgacctt actcggccag aagatgcaga gggaagtaaa gcaatgaatg     1860

gctctgcagc taaactacag cagtattatt gttggccaac aggaggtgcc actgtggctg     1920

aagcacgagt ctacagggac gcccgcggcc gtgccagcag cgagccacac attaagcgac     1980

caatgaatgc attcatggtt tgggcaaagg atgagaggag aaaaatcctt caggccttcc     2040

ccgacatgca taactccaac attagcaaaa tcttaggatc tcgctggaaa tcaatgtcca     2100

accaggagaa gcaaccttat tatgaagagc aggcccggct aagcaagatc cacttagaga     2160

agtacccaaa ctataaatac aaaccccgac cgaaacgcac ctgcattgtt gatggcaaaa     2220

agcttcggat tggggagtat aagcaactga tgaggtctcg gagacaggag atgaggcagt     2280

tctttactgt ggggcaacag cctcagattc caatcaccac aggaacaggt gttgtgtatc     2340

ctggtgctat cactatggca actaccacac catcgcctca gatgacatct gactgctcta     2400

gcacctcggc cagcccggag cccagcctcc cggtcatcca gagcacttat ggtatgaaga     2460

cagatggcgg aagcctagct ggaaatgaaa tgatcaatgg agaggatgaa atggaaatgt     2520

atgatgacta tgaagatgac cccaaatcag actatagcag tgaaaatgaa gccccggagg     2580

ctgtcagtgc caactgagga gtttttgttt gctgaattaa agtactctga catttcaccc     2640

ccctccccaa caaagagtta ttaaagagcc cgcatgcatt tgtggctcca caattacatc     2700

agcagaatgg tcttaattgt ttcgtaaagt gtgagacaga ttaagttttc cctgattttt     2760

catgaacttg agttttttgt tgttattgtt attgttgttg ttgttgtttt tttaatttag     2820

gtgaagacat attaaatatg agacaccagg acttgaaact tatctcaacc cgtagatgtc     2880

ttacaagtct tatatttttg tcttactttt tttttctttt ggatgttgat aaaggtttaa     2940

gttactgttt tagatggggt taaacattct cactcaggta tgctgtgccg gcctacaggt     3000

tgtgaatgtg tttttattct gaattatttt agaaaacaac tgaggatttc atattgtgaa     3060

acagaacaag tccacggcgt gtgcagctgc atgtagagca tattcaaaag gcctcggaat     3120

tccaattttc catttgtaga gttaaacttt gaatgtgcca aactttttcg taacttttga     3180

atcttaatat tttgaaagtc ttaaaggaga cactgcaaag tcttagacaa tctttggcat     3240

cttaaaataa aatagcaaac caacattttt ttttccagaa aatggtaagg tactcaggaa     3300

tctggagaca agatattgta aggaatgaac aaggttgcca cagtgcatgg acccaattgt     3360

gtttgcctgt tgacgtgcca tcagtgcgtg atgtggtatg acatacacac accagagcaa     3420

ccgccacacc agatatcgac agagtggtct tctctgcctg agaccacctc tcactacatc     3480

cattatccct ttgcctttaa ccctgacatt cagtcttaac acattttatc ttaaataatt     3540

tattcattcc agaatgtcaa gggtccactt gctatttatt ttttttcaat tgttggtggc     3600

attaatttaa taattcttgt ttttcacctt ccttccccga agaacttttc cgtccttttc     3660

acctccttct cctgtgtaca tagtgatttt atgtccccag aacgcctgga agcatttctg     3720

aaaccaagat attattaaaa acctattatt gtttttaatc atgagtatgt atctggctgc     3780

agggctgtgt attgggatat aggtatatag tcttacactt aaacaggtat gcccctgagg     3840

ttcactgtga cctcaagtct tttgccagaa ttttccccta attcagttca caagtggtag     3900

ggtctgcatc agtggcattt ccccctgaat tccattcagc agcaaggttc aacagtggtg     3960

actgccaggc aggagagtcc tgcggccaaa cctgaagccc aaggctcgtg ggccatgcag     4020

gaatctcagt gaagctgtca tgggctggca cctttacact gagttgcctt gtcccagctg     4080

gcacatctag ggagttcatt gcaaaatccc caggatgcaa aaagccacat gacagcctca     4140

gagcaaagat ggtggcaaat agtcatgata catctagaga atgaaagaaa actgtaaggg     4200

aggagaagga ggggaataca ttccctatat gggatgttcc tactgttaac tctggggaac     4260

agatagctcc gggggcagca gatgagttcc tctggctgac tctatctgta gccacatggg     4320

gacctgccta cgtgtgaaca aaatgaactg cacttatcac acaaggattt ctttgaagac     4380

atgctactgg ggtgggaagc agtgaggttt tattccccat ctcctaacta cagggagctc     4440

tgccatgtca ttttggcctt cctgaaacta ggacaggttg tctatcgggg ggcttccccc     4500

agagaggttt agtgggagaa tgtcagtgaa tgggatagtt cacctcatgg gacaacccag     4560

aatctgatca ccaggacata ggaatggccc catcagattt cttgagccat tttgtcactt     4620

ggaagaaaat agtgtacctt tgtatttatt taagagtgct caaggcctaa tagcaataaa     4680

caggtctagc caagaaatta caagctattc tgttagctgg gagtgctctc tataagctga     4740

ttaaggtact gataggaact ctttgttatt catgttggtt ggggattaga aatttgtttt     4800

tgtacattta tttcaaatga ggaggaggtc attttttctc tcaaaaaatg agtatttatt     4860

attgtcttac tgatttcttt gattatatac ctctcctcct cagttcactc ttgttttttt     4920

tctttctctt tggcttttgc ttttgctctc tctcacttct ttcttatttt gttgcattgg     4980

tagagtgttg tatggctagc attgtattgt atgtaattaa ttttgcacaa aagcaaacat     5040

ttagcatagt aggttaattt tgtttgtttt tatgaccatg ccaaaataat attctgggct     5100

ggtggagaac aaaggactgt tctttaggac tgaaacttga ttttgctcat agtaagtaaa     5160

aaaaaacaaa aaacacacac actcacagat gttgtttcgt aagtgttata agcactggat     5220

ataaatggta ttttttatca cttctgacta atgtgaaact gttgtacgaa aactacatga     5280

acaaaagtca tctgtttcga ctcgtgtggg cttgcctcac agttgccgga tttgagtcat     5340

ttttatgtct tgttatttca tttatttatg caaaatacat gtgtgtatga acactttgtt     5400

ttagctccag ctctgcctca gtactggggt tcatttactt ttagccatgt tcttaaaaat     5460

gaaaggctat tcaggaatga tctgattgta aacgtctttt tcattggatc aaacagtaat     5520

gctgtatttg aatctaaatt ttgtgtataa gcagtttatt tattagccaa gtttggctct     5580

aaatatccat ggaaattaag aatgacaatc atagggatca attcatttta ttttcagtgg     5640

ggcttaaaca aagtttatat gactttacca tctcatttta gatttttcta attgtgtaaa     5700

tataacatag aaatagaatt tatttttggt tcatgaatac ttagtgagat ataagttatg     5760

tatttccttt ttgttctcta tccatagatg ttggtccaaa ctgaaagttg atgagtcact     5820

gtgcctctcg gggtagtgag ttatcagcta cagtgagaga gcagtgtttg gcctgcagct     5880

gggacagcaa aacgtttcac cagggttctc atgcagttca gaacccactg tccacagatc     5940

cagacatttc ccttttttct tacagaaagt tgatgattgg acatactaaa tttccactac     6000

agttaggaga cagtcagttt gctttgggag tctacataaa tcttctaaga tagttctgtg     6060

accatttaat agcaagaagc atgaatgcca ctacaaaggc aaaaatccac ctctgagatc     6120

ggccgttaat aaacgtcccg tcatgtcagt ttagattcaa gaatgttaag caactttgtt     6180

tttgcggtgc tccctatttc atagtatctt caaatcaaaa ataaaaatta tctccatttt     6240

gttaaagaac ttacagggtc agggttctcc ttgtcactta gaattgggac actgccaggc     6300

aatcctctcc caaaaaaaaa aaaaaaaaaa aatagccata tggaatggaa ggaaaaggag     6360

aaaagaagga agaaaggaaa aaagtaggaa gggagagaga aaaaaaaggt cgctttgcgg     6420

atacgagccg ctaggctgac aacttttcta tttcattggc agatatgaag cagtgtcttt     6480

tccagtaagg tacggaagct ttgttgtttt catgtgtacc cagctcagcc ttttagaagc     6540

acctcggttt gcttcattag gtatttgata ctctccagcc ttgtcctcag gcctgatttg     6600

atttgccagg gtcctgacac caaagcccag gccaagttct aaattcaggt gtgggctcac     6660

agtgctattg agcttgtcga attctggcct cccctgaaca ttagccccac gggagcctga     6720

gggtgtttga aaagggcgtg atcactctag ggctgaaatt aaaggctgct ttcttttcct     6780

tctgaagcca ggctgcttct tcggagtaca ccctcctgag ccaggagcac aagcactagc     6840

agaaagcagg gattgtttca ggaaagccca tttaccctca gtaggaaggc agcctggtca     6900

cttgaacagc acagctgagg ctgcttctct caatttactc attttgcaaa gaattgacct     6960

ctaccaactc attagggaga ggaaaaagaa tcacttagta attttaaatc atatgagaag     7020

tcctgtacca agtgccaaca actgcaaaga aatgcagcta gaggaatgta ttgaaattac     7080

tactgggtct tcctttttaa tgagaaaatg acaaaaatgg ttgctgtagc cctgcctgat     7140

tttgtacacg tttgtctaag aattgagttg gcacttaagc tcacttctca aagtataata     7200

atattgtatg acctcatttg tcctttcaca aaagcacttg catcatttcc ttaagtcatc     7260

tgctccctga catgttttct tccctaataa acaacttctg tctgttattc ctgccaatga     7320

tgttctgttt ctgatgccat atcctattga gcgtgcccct gtactaatat cattgaaaat     7380

attgatatgc aaacacattt ccttttcatc cccattctat ctttcccttt ggggacagat     7440

tgctttccaa aagctcatga acaaatattt ggaatgctgg tacctttggg gcagaggtaa     7500

gggtgggcgg ggtgggggca gaaaggtaat gcttaatgca gataactctt ctaatcagtg     7560

tccatggcaa tatgaacgct tgaagaaaac tcagtgacat atcttgctca gtagtttctt     7620

attcctgaag aaccacaagc ataaagtgag gcctcagtgc tggtgctctt ggagtatggg     7680

gaatgtgcaa atatttaact gttttgtatg ctgcacattg caggtctgct catgtgcatt     7740

ctccctttgt cttcctttgt catatgtgtt tttgcttttt tgaaagtgca gtctttattg     7800

taccctcctc cagcttgtag caaattagaa tgcttagcat ttatgttcat tcattattgt     7860

atttgccatg taaaattttt attaccttag acaagcttat aagctgttac tacataactt     7920

atcttactgt aactctttta tttcccccga cgttgtaatt tgtttgtgat gtatattgtg     7980

aaattgtatt ctatgttaat ttaatcagca caattcactg acatgctgga ctgacatgct     8040

ggctgctgtt tcaaagtgta aagtttgtgt agggctgttg ggacaactgc aactctgttg     8100

tcaaggtact gtgctttggt tcctatagca acactgggtg tggcccttga attgctaagg     8160

gcatttaata catcctggag caaattttaa ctgcagattt tctttgtaga aattctatgt     8220

ataatgcagg tacctacttg gcccatggct ggtaactatt tgggcaatta gaaaaaaaga     8280

aaaaaacata aaaactagtg tctattgctg ctttgaatat gtttgaaagt ctgaaaatgt     8340

aaatagttta tcaaaaaaaa atcttgtaca gtccagtgta aagtttttaa atgaccttaa     8400

gggttgccat cacatctttc tcacactctc ctcttgataa taataataat aaaaagtttg     8460

ctaaggatta aagaaatggg aaaaataaaa aaaatctctt caaatttaca ggaatgaatc     8520

attgttctta gctttgttgc atacacaaac ttcttggatt ttgttgtgca gtattgacgt     8580

gagataaagc tcaacattga ataatctttc agtggtactt ttcaaagtct tcccctcctc     8640

tgcctcataa ttaagggaaa agacaaaatt gaaagacaca ctgtctttat ctatcctggt     8700

gtatgttggc accttagcta cttttttttt ttcctttttg cacaaggtgc tttcctgata     8760

tgttcaacat gccatctttg ggtgataatg tatatgccgt gatggggctc aggcccctta     8820

ggggagtgtc tataagaact gcctatttat gctcatttac ctcaagactg tcctctctac     8880

cctaatctag ttgtcatcac tccatctttt gtactgctgt tgacacttac aaattaaaga     8940

taaattttgt tttatga                                                    8957


<210>  1088
<211>  8919
<212>  DNA
<213>  homo sapiens

<400>  1088
agttgttagg agagaccatt ggggatagga aagatgaaag gtcatggtga gcttcaagga       60

catgaaagaa gaatgtcttc caagcaagcc acctctccat ttgcctgtgc agctgatgga      120

gaggatgcaa tgacccagga tttaacctca agggaaaagg aagagggcag tgatcaacat      180

gtggcctccc atctgcctct gcaccccata atgcacaaca aacctcactc tgaggagcta      240

ccaacacttg tcagtaccat tcaacaagat gctgactggg acagcgttct gtcatctcag      300

caaagaatgg aatcagagaa taataagtta tgttccctat attccttccg aaatacctct      360

acctcaccac ataagcctga cgaagggagt cgggaccgtg agataatgac cagtgttact      420

tttggaaccc cagagcgccg caaagggagt cttgccgatg tggtggacac actgaaacag      480

aagaagcttg aggaaatgac tcggactgaa caagaggatt cctcctgcat ggaaaaacta      540

ctttcaaaag attggaagga aaaaatggaa agactaaata ccagtgaact tcttggagaa      600

attaaaggta cacctgagag cctggcagaa aaagaacggc agctctccac catgattacc      660

cagctgatca gtttacggga gcagctactg gcagcgcatg atgaacagaa aaaactggca      720

gcgtcacaaa ttgagaaaca acggcagcaa atggaccttg ctcgccaaca gcaagaacag      780

attgcgagac aacagcagca acttctgcaa cagcagcaca aaattaatct cctgcagcaa      840

cagatccagg ttcagggtca catgcctccg ctcatgatcc caatttttcc acatgaccag      900

cggactctgg cagcagctgc tgctgcccaa cagggattcc tcttcccccc tggaataaca      960

tacaaaccag gtgataacta ccccgtacag ttcattccat caacaatggc agctgctgct     1020

gcttctggac tcagcccttt acagctccag aagggtcatg tctcccaccc acaaattaac     1080

caaaggctaa agggcctaag tgaccgtttt ggcaggaatt tggacacctt tgaacatggt     1140

ggtggccact cttacaacca caaacagatt gagcagctct atgccgctca gctggccagc     1200

atgcaggtgt cacctggagc aaagatgcca tcaactccac agccaccaaa cacagcaggg     1260

acggtctcac ctactgggat aaaaaatgaa aagagaggga ccagccctgt aactcaagtt     1320

aaggatgaag cagcagcaca gcctctgaat ctctcatccc gacccaagac agcagagcct     1380

gtaaagtccc caacgtctcc cacccagaac ctcttcccag ccagcaaaac cagccctgtc     1440

aatctgccaa acaaaagcag catccctagc cccattggag gaagcctggg aagaggatcc     1500

tctttagata tcctatctag tctcaactcc cctgcccttt ttggggatca ggatacagtg     1560

atgaaagcca ttcaggaggc gcggaagatg cgagagcaga tccagcggga gcaacagcag     1620

caacagccac atggtgttga cgggaaactg tcctccataa ataatatggg gctgaacagc     1680

tgcaggaatg aaaaggaaag aacgcgcttt gagaatttgg ggccccagtt aacgggaaag     1740

tcaaatgaag atggaaaact gggcccaggt gtcatcgacc ttactcggcc agaagatgca     1800

gagggaagta aagcaatgaa tggctctgca gctaaactac agcagtatta ttgttggcca     1860

acaggaggtg ccactgtggc tgaagcacga gtctacaggg acgcccgcgg ccgtgccagc     1920

agcgagccac acattaagcg accaatgaat gcattcatgg tttgggcaaa ggatgagagg     1980

agaaaaatcc ttcaggcctt ccccgacatg cataactcca acattagcaa aatcttagga     2040

tctcgctgga aatcaatgtc caaccaggag aagcaacctt attatgaaga gcaggcccgg     2100

ctaagcaaga tccacttaga gaagtaccca aactataaat acaaaccccg accgaaacgc     2160

acctgcattg ttgatggcaa aaagcttcgg attggggagt ataagcaact gatgaggtct     2220

cggagacagg agatgaggca gttctttact gtggggcaac agcctcagat tccaatcacc     2280

acaggaacag gtgttgtgta tcctggtgct atcactatgg caactaccac accatcgcct     2340

cagatgacat ctgactgctc tagcacctcg gccagcccgg agcccagcct cccggtcatc     2400

cagagcactt atggtatgaa gacagatggc ggaagcctag ctggaaatga aatgatcaat     2460

ggagaggatg aaatggaaat gtatgatgac tatgaagatg accccaaatc agactatagc     2520

agtgaaaatg aagccccgga ggctgtcagt gccaactgag gagtttttgt ttgctgaatt     2580

aaagtactct gacatttcac ccccctcccc aacaaagagt tattaaagag cccgcatgca     2640

tttgtggctc cacaattaca tcagcagaat ggtcttaatt gtttcgtaaa gtgtgagaca     2700

gattaagttt tccctgattt ttcatgaact tgagtttttt gttgttattg ttattgttgt     2760

tgttgttgtt tttttaattt aggtgaagac atattaaata tgagacacca ggacttgaaa     2820

cttatctcaa cccgtagatg tcttacaagt cttatatttt tgtcttactt tttttttctt     2880

ttggatgttg ataaaggttt aagttactgt tttagatggg gttaaacatt ctcactcagg     2940

tatgctgtgc cggcctacag gttgtgaatg tgtttttatt ctgaattatt ttagaaaaca     3000

actgaggatt tcatattgtg aaacagaaca agtccacggc gtgtgcagct gcatgtagag     3060

catattcaaa aggcctcgga attccaattt tccatttgta gagttaaact ttgaatgtgc     3120

caaacttttt cgtaactttt gaatcttaat attttgaaag tcttaaagga gacactgcaa     3180

agtcttagac aatctttggc atcttaaaat aaaatagcaa accaacattt ttttttccag     3240

aaaatggtaa ggtactcagg aatctggaga caagatattg taaggaatga acaaggttgc     3300

cacagtgcat ggacccaatt gtgtttgcct gttgacgtgc catcagtgcg tgatgtggta     3360

tgacatacac acaccagagc aaccgccaca ccagatatcg acagagtggt cttctctgcc     3420

tgagaccacc tctcactaca tccattatcc ctttgccttt aaccctgaca ttcagtctta     3480

acacatttta tcttaaataa tttattcatt ccagaatgtc aagggtccac ttgctattta     3540

ttttttttca attgttggtg gcattaattt aataattctt gtttttcacc ttccttcccc     3600

gaagaacttt tccgtccttt tcacctcctt ctcctgtgta catagtgatt ttatgtcccc     3660

agaacgcctg gaagcatttc tgaaaccaag atattattaa aaacctatta ttgtttttaa     3720

tcatgagtat gtatctggct gcagggctgt gtattgggat ataggtatat agtcttacac     3780

ttaaacaggt atgcccctga ggttcactgt gacctcaagt cttttgccag aattttcccc     3840

taattcagtt cacaagtggt agggtctgca tcagtggcat ttccccctga attccattca     3900

gcagcaaggt tcaacagtgg tgactgccag gcaggagagt cctgcggcca aacctgaagc     3960

ccaaggctcg tgggccatgc aggaatctca gtgaagctgt catgggctgg cacctttaca     4020

ctgagttgcc ttgtcccagc tggcacatct agggagttca ttgcaaaatc cccaggatgc     4080

aaaaagccac atgacagcct cagagcaaag atggtggcaa atagtcatga tacatctaga     4140

gaatgaaaga aaactgtaag ggaggagaag gaggggaata cattccctat atgggatgtt     4200

cctactgtta actctgggga acagatagct ccgggggcag cagatgagtt cctctggctg     4260

actctatctg tagccacatg gggacctgcc tacgtgtgaa caaaatgaac tgcacttatc     4320

acacaaggat ttctttgaag acatgctact ggggtgggaa gcagtgaggt tttattcccc     4380

atctcctaac tacagggagc tctgccatgt cattttggcc ttcctgaaac taggacaggt     4440

tgtctatcgg ggggcttccc ccagagaggt ttagtgggag aatgtcagtg aatgggatag     4500

ttcacctcat gggacaaccc agaatctgat caccaggaca taggaatggc cccatcagat     4560

ttcttgagcc attttgtcac ttggaagaaa atagtgtacc tttgtattta tttaagagtg     4620

ctcaaggcct aatagcaata aacaggtcta gccaagaaat tacaagctat tctgttagct     4680

gggagtgctc tctataagct gattaaggta ctgataggaa ctctttgtta ttcatgttgg     4740

ttggggatta gaaatttgtt tttgtacatt tatttcaaat gaggaggagg tcattttttc     4800

tctcaaaaaa tgagtattta ttattgtctt actgatttct ttgattatat acctctcctc     4860

ctcagttcac tcttgttttt tttctttctc tttggctttt gcttttgctc tctctcactt     4920

ctttcttatt ttgttgcatt ggtagagtgt tgtatggcta gcattgtatt gtatgtaatt     4980

aattttgcac aaaagcaaac atttagcata gtaggttaat tttgtttgtt tttatgacca     5040

tgccaaaata atattctggg ctggtggaga acaaaggact gttctttagg actgaaactt     5100

gattttgctc atagtaagta aaaaaaaaca aaaaacacac acactcacag atgttgtttc     5160

gtaagtgtta taagcactgg atataaatgg tattttttat cacttctgac taatgtgaaa     5220

ctgttgtacg aaaactacat gaacaaaagt catctgtttc gactcgtgtg ggcttgcctc     5280

acagttgccg gatttgagtc atttttatgt cttgttattt catttattta tgcaaaatac     5340

atgtgtgtat gaacactttg ttttagctcc agctctgcct cagtactggg gttcatttac     5400

ttttagccat gttcttaaaa atgaaaggct attcaggaat gatctgattg taaacgtctt     5460

tttcattgga tcaaacagta atgctgtatt tgaatctaaa ttttgtgtat aagcagttta     5520

tttattagcc aagtttggct ctaaatatcc atggaaatta agaatgacaa tcatagggat     5580

caattcattt tattttcagt ggggcttaaa caaagtttat atgactttac catctcattt     5640

tagatttttc taattgtgta aatataacat agaaatagaa tttatttttg gttcatgaat     5700

acttagtgag atataagtta tgtatttcct ttttgttctc tatccataga tgttggtcca     5760

aactgaaagt tgatgagtca ctgtgcctct cggggtagtg agttatcagc tacagtgaga     5820

gagcagtgtt tggcctgcag ctgggacagc aaaacgtttc accagggttc tcatgcagtt     5880

cagaacccac tgtccacaga tccagacatt tccctttttt cttacagaaa gttgatgatt     5940

ggacatacta aatttccact acagttagga gacagtcagt ttgctttggg agtctacata     6000

aatcttctaa gatagttctg tgaccattta atagcaagaa gcatgaatgc cactacaaag     6060

gcaaaaatcc acctctgaga tcggccgtta ataaacgtcc cgtcatgtca gtttagattc     6120

aagaatgtta agcaactttg tttttgcggt gctccctatt tcatagtatc ttcaaatcaa     6180

aaataaaaat tatctccatt ttgttaaaga acttacaggg tcagggttct ccttgtcact     6240

tagaattggg acactgccag gcaatcctct cccaaaaaaa aaaaaaaaaa aaaatagcca     6300

tatggaatgg aaggaaaagg agaaaagaag gaagaaagga aaaaagtagg aagggagaga     6360

gaaaaaaaag gtcgctttgc ggatacgagc cgctaggctg acaacttttc tatttcattg     6420

gcagatatga agcagtgtct tttccagtaa ggtacggaag ctttgttgtt ttcatgtgta     6480

cccagctcag ccttttagaa gcacctcggt ttgcttcatt aggtatttga tactctccag     6540

ccttgtcctc aggcctgatt tgatttgcca gggtcctgac accaaagccc aggccaagtt     6600

ctaaattcag gtgtgggctc acagtgctat tgagcttgtc gaattctggc ctcccctgaa     6660

cattagcccc acgggagcct gagggtgttt gaaaagggcg tgatcactct agggctgaaa     6720

ttaaaggctg ctttcttttc cttctgaagc caggctgctt cttcggagta caccctcctg     6780

agccaggagc acaagcacta gcagaaagca gggattgttt caggaaagcc catttaccct     6840

cagtaggaag gcagcctggt cacttgaaca gcacagctga ggctgcttct ctcaatttac     6900

tcattttgca aagaattgac ctctaccaac tcattaggga gaggaaaaag aatcacttag     6960

taattttaaa tcatatgaga agtcctgtac caagtgccaa caactgcaaa gaaatgcagc     7020

tagaggaatg tattgaaatt actactgggt cttccttttt aatgagaaaa tgacaaaaat     7080

ggttgctgta gccctgcctg attttgtaca cgtttgtcta agaattgagt tggcacttaa     7140

gctcacttct caaagtataa taatattgta tgacctcatt tgtcctttca caaaagcact     7200

tgcatcattt ccttaagtca tctgctccct gacatgtttt cttccctaat aaacaacttc     7260

tgtctgttat tcctgccaat gatgttctgt ttctgatgcc atatcctatt gagcgtgccc     7320

ctgtactaat atcattgaaa atattgatat gcaaacacat ttccttttca tccccattct     7380

atctttccct ttggggacag attgctttcc aaaagctcat gaacaaatat ttggaatgct     7440

ggtacctttg gggcagaggt aagggtgggc ggggtggggg cagaaaggta atgcttaatg     7500

cagataactc ttctaatcag tgtccatggc aatatgaacg cttgaagaaa actcagtgac     7560

atatcttgct cagtagtttc ttattcctga agaaccacaa gcataaagtg aggcctcagt     7620

gctggtgctc ttggagtatg gggaatgtgc aaatatttaa ctgttttgta tgctgcacat     7680

tgcaggtctg ctcatgtgca ttctcccttt gtcttccttt gtcatatgtg tttttgcttt     7740

tttgaaagtg cagtctttat tgtaccctcc tccagcttgt agcaaattag aatgcttagc     7800

atttatgttc attcattatt gtatttgcca tgtaaaattt ttattacctt agacaagctt     7860

ataagctgtt actacataac ttatcttact gtaactcttt tatttccccc gacgttgtaa     7920

tttgtttgtg atgtatattg tgaaattgta ttctatgtta atttaatcag cacaattcac     7980

tgacatgctg gactgacatg ctggctgctg tttcaaagtg taaagtttgt gtagggctgt     8040

tgggacaact gcaactctgt tgtcaaggta ctgtgctttg gttcctatag caacactggg     8100

tgtggccctt gaattgctaa gggcatttaa tacatcctgg agcaaatttt aactgcagat     8160

tttctttgta gaaattctat gtataatgca ggtacctact tggcccatgg ctggtaacta     8220

tttgggcaat tagaaaaaaa gaaaaaaaca taaaaactag tgtctattgc tgctttgaat     8280

atgtttgaaa gtctgaaaat gtaaatagtt tatcaaaaaa aaatcttgta cagtccagtg     8340

taaagttttt aaatgacctt aagggttgcc atcacatctt tctcacactc tcctcttgat     8400

aataataata ataaaaagtt tgctaaggat taaagaaatg ggaaaaataa aaaaaatctc     8460

ttcaaattta caggaatgaa tcattgttct tagctttgtt gcatacacaa acttcttgga     8520

ttttgttgtg cagtattgac gtgagataaa gctcaacatt gaataatctt tcagtggtac     8580

ttttcaaagt cttcccctcc tctgcctcat aattaaggga aaagacaaaa ttgaaagaca     8640

cactgtcttt atctatcctg gtgtatgttg gcaccttagc tacttttttt ttttcctttt     8700

tgcacaaggt gctttcctga tatgttcaac atgccatctt tgggtgataa tgtatatgcc     8760

gtgatggggc tcaggcccct taggggagtg tctataagaa ctgcctattt atgctcattt     8820

acctcaagac tgtcctctct accctaatct agttgtcatc actccatctt ttgtactgct     8880

gttgacactt acaaattaaa gataaatttt gttttatga                            8919


<210>  1089
<211>  3435
<212>  DNA
<213>  homo sapiens

<400>  1089
tgccctcccg cggctgcagc cggagccgaa ggtggtggct gcacagtaga cgccccctca       60

cggcttcccc cacacgctcc cgccccctcg ctcgcccatc gcgcttccct cacaggctct      120

gcagtcctcc cccacagacg ccttccccct tggactctca ttcccttttc cacggagccc      180

cgcgctttcg tgagccccct cgaggaacct ggtctccgca tccagttacc acctcctgcc      240

tcagaggcca tctgagccct tcgcacctcg cccctcagtc cccccttccc cccccgcccg      300

cgtcgcctcg ctccctcccg cccccccatc atcccttccc tcgcagttcc cctgtcctga      360

ggggagcccc gccacgggca gcgcggcggc ggcggcagga gggagaaagt gaagcggtag      420

ctcgcgcaca ctcgcgccct cactcccggc taggcggcac ccaccgccgg gaggaggagg      480

aggagccgag aggagctgag cgagcgcgga agtagctgct gctggtggtg acaatgtcaa      540

ataacggcct agacattcaa gacaaacccc cagcccctcc gatgagaaat accagcacta      600

tgattggagc cggcagcaaa gatgctggaa ccctaaacca tggttctaaa cctctgcctc      660

caaacccaga ggagaagaaa aagaaggacc gattttaccg atccatttta cctggagata      720

aaacaaataa aaagaaagag aaagagcggc cagagatttc tctcccttca gattttgaac      780

acacaattca tgtcggtttt gatgctgtca caggggagtt tacgggaatg ccagagcagt      840

gggcccgctt gcttcagaca tcaaatatca ctaagtcgga gcagaagaaa aacccgcagg      900

ctgttctgga tgtgttggag ttttacaact cgaagaagac atccaacagc cagaaataca      960

tgagctttac agataagtca gctgaggatt acaattcttc taatgccttg aatgtgaagg     1020

ctgtgtctga gactcctgca gtgccaccag tttcagaaga tgaggatgat gatgatgatg     1080

atgctacccc accaccagtg attgctccac gcccagagca cacaaaatct gtatacacac     1140

ggtctgtgat tgaaccactt cctgtcactc caactcggga cgtggctaca tctcccattt     1200

cacctactga aaataacacc actccaccag atgctttgac ccggaatact gagaagcaga     1260

agaagaagcc taaaatgtct gatgaggaga tcttggagaa attacgaagc atagtgagtg     1320

tgggcgatcc taagaagaaa tatacacggt ttgagaagat tggacaaggt gcttcaggca     1380

ccgtgtacac agcaatggat gtggccacag gacaggaggt ggccattaag cagatgaatc     1440

ttcagcagca gcccaagaaa gagctgatta ttaatgagat cctggtcatg agggaaaaca     1500

agaacccaaa cattgtgaat tacttggaca gttacctcgt gggagatgag ctgtgggttg     1560

ttatggaata cttggctgga ggctccttga cagatgtggt gacagaaact tgcatggatg     1620

aaggccaaat tgcagctgtg tgccgtgagt gtctgcaggc tctggagttc ttgcattcga     1680

accaggtcat tcacagagac atcaagagtg acaatattct gttgggaatg gatggctctg     1740

tcaagctaac tgactttgga ttctgtgcac agataacccc agagcagagc aaacggagca     1800

ccatggtagg aaccccatac tggatggcac cagaggttgt gacacgaaag gcctatgggc     1860

ccaaggttga catctggtcc ctgggcatca tggccatcga aatgattgaa ggggagcctc     1920

catacctcaa tgaaaaccct ctgagagcct tgtacctcat tgccaccaat gggaccccag     1980

aacttcagaa cccagagaag ctgtcagcta tcttccggga ctttctgaac cgctgtctcg     2040

agatggatgt ggagaagaga ggttcagcta aagagctgct acagcatcaa ttcctgaaga     2100

ttgccaagcc cctctccagc ctcactccac tgattgctgc agctaaggag gcaacaaaga     2160

acaatcacta aaaccacact caccccagcc tcattgtgcc aagccttctg tgagataaat     2220

gcacatttca gaaattccaa ctcctgatgc cctcttctcc ttgccttgct tctcccattt     2280

cctgatctag cactcctcaa gactttgatc cttggaaacc gtgtgtccag cattgaagag     2340

aactgcaact gaatgactaa tcagatgatg gccatttcta aataaggaat ttcctcccaa     2400

ttcatggata tgagggtggt ttatgattaa gggtttatat aaataaatgt ttctagtctt     2460

ccgtgtgtca aaatcctcac ctccttcata accatctccc acaattaatt cttgactata     2520

taaatttatg gtttgataat attatcaatt tgtaatcaat tgagatttct ttagtgcttg     2580

cttttctgtg actcaactgc ccagacacct cattgtactt gaaaactgga acagcttggg     2640

aatgccatgg ggtttgataa tctgccaggg acatgaagag gctcagcttc ctggaccatg     2700

actttggctc agctgatcct gacatgggag aacaaccaca tttttctttg tgtgtgcttc     2760

tagcagctgt tcgggaggac cttgacccaa tagtgttccc atgctgtttc ttgtgaaatg     2820

ctctcggcta tgtagcagct tttgattccc tgcataccct aggctgctgc ccctatcctg     2880

tcccttgttt ataacattga gaggttttct agggcacata ctgagtgaga gcagtgttga     2940

gaagtcgggg aaaatggtga ctacttttag agcaaggctg ggcatcagca cctgtccagc     3000

tctacttgtg tgatgtttca ggaactcagc ccctttttct gcctaggata aggagctgaa     3060

agattaactt ggatcttcta atggtccaaa tcttttggtc acaataaaga gtctccaaat     3120

tagagactgc atgttagttc tggatggatt tggtggcctg acatgatacc ctgccagctg     3180

tgaggggacc ccgtttttaa gatgcatggc caagctctct gcaaatggaa atgcttacac     3240

tgggtgttgg ggatgtttgc tacctcctgc tatttttgtg gttttggttc tcccactatg     3300

gtaggacccc tggccagcat tgtggcttgt catgtcagcc ccattgacta ccttctcatg     3360

ctctgaggta ctactgcctc tgcagcacaa atttctattt ctgtcaataa aaggagatga     3420

aaatattcta aaaaa                                                      3435


<210>  1090
<211>  1572
<212>  DNA
<213>  homo sapiens

<400>  1090
gggtgctccg ccctccccgc aggcggcgtg cggctgcata gcctgagaat cccggtggtg       60

agcggggatg gcggttgtag cggcggctgc cggctggcta ctcaggctca gggcggcagg      120

ggctgagggg cactggcgtc ggcttcctgg cgcggggctg gcgcggggct ttttgcaccc      180

cgccgcgact gtcgaggatg cggcccagag gcggcaggtg gctcatttta ctttccagcc      240

agatccggag ccccgggagt acgggcaaac tcagaaaatg aatcttttcc agtctgtaac      300

aagtgccttg gataactcat tggccaaaga tcctactgca gtaatatttg gtgaagatgt      360

tgcctttggt ggagtcttta gatgcactgt tggcttgcga gacaaatatg gaaaagatag      420

agtttttaat accccattgt gtgaacaagg aattgttgga tttggaatcg gaattgcggt      480

cactggagct actgccattg cggaaattca gtttgcagat tatattttcc ctgcatttga      540

tcagattgtt aatgaagctg ccaagtatcg ctatcgctct ggggatcttt ttaactgtgg      600

aagcctcact atccggtccc cttggggctg tgttggtcat ggggctctct atcattctca      660

gagtcctgaa gcattttttg cccattgccc aggaatcaag gtggttatac ccagaagccc      720

tttccaggcc aaaggacttc ttttgtcatg catagaggat aaaaatcctt gtatattttt      780

tgaacctaaa atactttaca gggcagcagc ggaagaagtc cctatagaac catacaacat      840

cccactgtcc caggccgaag tcatacagga agggagtgat gttactctag ttgcctgggg      900

cactcaggtt catgtgatcc gagaggtagc ttccatggca aaagaaaagc ttggagtgtc      960

ttgtgaagtc attgatctga ggactataat accttgggat gtggacacaa tttgtaagtc     1020

tgtgatcaaa acagggcgac tgctaatcag tcacgaggct cccttgacag gcggctttgc     1080

atcggaaatc agctctacag ttcaggagga atgtttcttg aacctagagg ctcctatatc     1140

aagagtatgt ggttatgaca caccatttcc tcacattttt gaaccattct acatcccaga     1200

caaatggaag tgttatgatg cccttcgaaa aatgatcaac tattgaccat atagaaaagc     1260

tggaagatta tgactagata tggaaatatt ttttctgaat ttttttttat atttcctccg     1320

acttacctct ttttgaaaag agagttttta ttaagtgaac catcacgata ttggctgaaa     1380

agttctacat tctattattg tattgtaaca cacatgtatt gatgattttc attaagagtt     1440

tcagattaac tttgaaaaat attccacatg gtaatcttat aaattctgtt taattacatc     1500

tgtaaatatt atgtgtgtga tagtattcaa taaagtaaaa tcaaattgtc aaaaaaaaaa     1560

aaaaaaaaaa aa                                                         1572


<210>  1091
<211>  2685
<212>  DNA
<213>  homo sapiens

<400>  1091
tcccgcccgc gccctgccca ccccggccgc gcgcaccaca acgcccccgc cccgccgccc       60

ggaaccagct gagcgcagct ggacccagca gccgctgtct ccagtgccgc agcagcaggt      120

agtgctcata gctctctttg tccagtgctt cggccttggt cccagcgcct tcccacggag      180

cagcactctt caccctgcac agccttgtta gcccaacagc atggtggtgg aacaccccga      240

gttcctcaag gcagggaagg agcctggcct gcagatctgg cgtgtggaga agttcgatct      300

ggtgcccgtg cccaccaacc tttatggaga cttcttcacg ggcgacgcct acgtcatcct      360

gaagacagtg cagctgagga acggaaatct gcagtatgac ctccactact ggctgggcaa      420

tgagtgcagc caggatgaga gcggggcggc cgccatcttt accgtgcagc tggatgacta      480

cctgaacggc cgggccgtgc agcaccgtga ggtccagggc ttcgagtcgg ccaccttcct      540

aggctacttc aagtctggcc tgaagtacaa gaaaggaggt gtggcatcag gattcaagca      600

cgtggtaccc aacgaggtgg tggtgcagag actcttccag gtcaaagggc ggcgtgtggt      660

ccgtgccacc gaggtacctg tgtcctggga gagcttcaac aatggcgact gcttcatcct      720

ggacctgggc aacaacatcc accagtggtg tggttccaac agcaatcggt atgaaagact      780

gaaggccaca caggtgtcca agggcatccg ggacaacgag cggagtggcc gggcccgagt      840

gcacgtgtct gaggagggca ctgagcccga ggcgatgctc caggtgctgg gccccaagcc      900

ggctctgcct gcaggtaccg aggacaccgc caaggaggat gcggccaacc gcaagctggc      960

caagctctac aaggtctcca atggtgcagg gaccatgtcc gtctccctcg tggctgatga     1020

gaaccccttc gcccaggggg ccctgaagtc agaggactgc ttcatcctgg accacggcaa     1080

agatgggaaa atctttgtct ggaaaggcaa gcaggcaaac acggaggaga ggaaggctgc     1140

cctcaaaaca gcctctgact tcatcaccaa gatggactac cccaagcaga ctcaggtctc     1200

ggtccttcct gagggcggtg agaccccact gttcaagcag ttcttcaaga actggcggga     1260

cccagaccag acagatggcc tgggcttgtc ctacctttcc agccatatcg ccaacgtgga     1320

gcgggtgccc ttcgacgccg ccaccctgca cacctccact gccatggccg cccagcacgg     1380

catggatgac gatggcacag gccagaaaca gatctggaga atcgaaggtt ccaacaaggt     1440

gcccgtggac cctgccacat atggacagtt ctatggaggc gacagctaca tcattctgta     1500

caactaccgc catggtggcc gccaggggca gataatctat aactggcagg gtgcccagtc     1560

tacccaggat gaggtcgctg catctgccat cctgactgct cagctggatg aggagctggg     1620

aggtacccct gtccagagcc gtgtggtcca aggcaaggag cccgcccacc tcatgagcct     1680

gtttggtggg aagcccatga tcatctacaa gggcggcacc tcccgcgagg gcgggcagac     1740

agcccctgcc agcacccgcc tcttccaggt ccgcgccaac agcgctggag ccacccgggc     1800

tgttgaggta ttgcctaagg ctggtgcact gaactccaac gatgcctttg ttctgaaaac     1860

cccctcagcc gcctacctgt gggtgggtac aggagccagc gaggcagaga agacgggggc     1920

ccaggagctg ctcagggtgc tgcgggccca acctgtgcag gtggcagaag gcagcgagcc     1980

agatggcttc tgggaggccc tgggcgggaa ggctgcctac cgcacatccc cacggctgaa     2040

ggacaagaag atggatgccc atcctcctcg cctctttgcc tgctccaaca agattggacg     2100

ttttgtgatc gaagaggttc ctggtgagct catgcaggaa gacctggcaa cggatgacgt     2160

catgcttctg gacacctggg accaggtctt tgtctgggtt ggaaaggatt ctcaagaaga     2220

agaaaagaca gaagccttga cttctgctaa gcggtacatc gagacggacc cagccaatcg     2280

ggatcggcgg acgcccatca ccgtggtgaa gcaaggcttt gagcctccct cctttgtggg     2340

ctggttcctt ggctgggatg atgattactg gtctgtggac cccttggaca gggccatggc     2400

tgagctggct gcctgaggag gggcagggcc cacccatgtc accggtcagt gccttttgga     2460

actgtccttc cctcaaagag gccttagagc gagcagagca gctctgctat gagtgtgtgt     2520

gtgtgtgtgt gttgtttctt tttttttttt ttacagtatc caaaaatagc cctgcaaaaa     2580

ttcagagtcc ttgcaaaatt gtctaaaatg tcagtgtttg ggaaattaaa tccaataaaa     2640

acattttgaa gtgtgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                     2685


<210>  1092
<211>  1955
<212>  DNA
<213>  homo sapiens

<400>  1092
attcatcccc attcaggctt tcctcagcat ttattaagga ctctctgctc cagcctctca       60

ctctcactct cctccgctca aactcagctc acttgagagt ctcctcccgc cagctgtgga      120

aagaactttg cgtctctcca gcaatgcatc tccttgcgat tctgttttgt gctctctggt      180

ctgcagtgtt ggccgagaac tcggatgatt atgatctcat gtatgtgaat ttggacaacg      240

aaatagacaa tggactccat cccactgagg accccacgcc gtgcgcctgc ggtcaggagc      300

actcggaatg ggacaagctc ttcatcatgc tggagaactc gcagatgaga gagcgcatgc      360

tgctgcaagc cacggacgac gtcctgcggg gcgagctgca gaggctgcgg gaggagctgg      420

gccggctcgc ggaaagcctg gcgaggccgt gcgcgccggg ggctcccgca gaggccaggc      480

tgaccagtgc tctggacgag ctgctgcagg cgacccgcga cgcgggccgc aggctggcgc      540

gtatggaggg cgcggaggcg cagcgcccag aggaggcggg gcgcgccctg gccgcggtgc      600

tagaggagct gcggcagacg cgagccgacc tgcacgcggt gcagggctgg gctgcccgga      660

gctggctgcc ggcaggttgt gaaacagcta ttttattccc aatgcgttcc aagaagattt      720

ttggaagcgt gcatccagtg agaccaatga ggcttgagtc ttttagtgcc tgcatttggg      780

tcaaagccac agatgtatta aacaaaacca tcctgttttc ctatggcaca aagaggaatc      840

catatgaaat ccagctgtat ctcagctacc aatccatagt gtttgtggtg ggtggagagg      900

agaacaaact ggttgctgaa gccatggttt ccctgggaag gtggacccac ctgtgcggca      960

cctggaattc agaggaaggg ctcacatcct tgtgggtaaa tggtgaactg gcggctacca     1020

ctgttgagat ggccacaggt cacattgttc ctgagggagg aatcctgcag attggccaag     1080

aaaagaatgg ctgctgtgtg ggtggtggct ttgatgaaac attagccttc tctgggagac     1140

tcacaggctt caatatctgg gatagtgttc ttagcaatga agagataaga gagaccggag     1200

gagcagagtc ttgtcacatc cgggggaata ttgttgggtg gggagtcaca gagatccagc     1260

cacatggagg agctcagtat gtttcataaa tgttgtgaaa ctccacttga agccaaagaa     1320

agaaactcac acttaaaaca catgccagtt gggaaggtct gaaaactcag tgcataatag     1380

gaacacttga gactaatgaa agagagagtt gagaccaatc tttatttgta ctggccaaat     1440

actgaataaa cagttgaagg aaagacattg gaaaaagctt ttgaggataa tgttactaga     1500

ctttatgcca tggtgctttc agtttaatgc tgtgtctctg tcagataaac tctcaaataa     1560

ttaaaaagga ctgtattgtt gaacagaggg acaattgttt tacttttctt tggttaattt     1620

tgttttggcc agagatgaat tttacattgg aagaataaca aaataagatt tgttgtccat     1680

tgttcattgt tattggtatg taccttatta caaaaaaaag atgaaaacat atttatacta     1740

caaggtgact taacaactat aaatgtagtt tatgtgttat aatcgaatgt cacgtttttg     1800

agaagatagt catataagtt atattgcaaa agggatttgt attaatttaa gactattttt     1860

gtaaagctct actgtaaata aaatatttta taaaactagc tcacgtcatt taattataaa     1920

tttaagagat gttttggaaa aaaaaaaaaa aaaaa                                1955


<210>  1093
<211>  3712
<212>  DNA
<213>  homo sapiens

<400>  1093
gggtgctccg ccctccccgc aggcggcgtg cggctgcata gcctgagaat cccggtggtg       60

agcggggatg gcggttgtag cggcggctgc cggctggcta ctcaggctca gggcggcagg      120

ggctgagggg cactggcgtc ggcttcctgg cgcggggctg gcgcggggct ttttgcaccc      180

cgccgcgact gtcgaggatg cggcccagag gcggcaggtg gctcatttta ctttccagcc      240

agatccggag ccccgggagt acgggcaaac tcagaaaatg aatcttttcc agtctgtaac      300

aagtgccttg gataactcat tggccaaaga tcctactgca gtaatatttg gtgaagatgt      360

tgcctttggt ggagtcttta gatgcactgt tggcttgcga gacaaatatg gaaaagatag      420

agtttttaat accccattgt gtgaacaagg aattgttgga tttggaatcg gaattgcggt      480

cactggagct actgccattg cggaaattca gtttgcagat tatattttcc ctgcatttga      540

tcagattgtt aatgaagctg ccaagtatcg ctatcgctct ggggatcttt ttaactgtgg      600

aagcctcact atccggtccc cttggggctg tgttggtcat ggggctctct atcattctca      660

gagtcctgaa gcattttttg cccattgccc aggaatcaag gtggttatac ccagaagccc      720

tttccaggcc aaaggacttc ttttgtcatg catagaggat aaaaatcctt gtatattttt      780

tgaacctaaa atactttaca gggcagcagc ggaagaagtc cctatagaac catacaacat      840

cccactgtcc caggccgaag tcatacagga agggagtgat gttactctag ttgcctgggg      900

cactcaggtt catgtgatcc gagaggtagc ttccatggca aaagaaaagc ttggagtgtc      960

ttgtgaagtc attgatctga ggactataat accttgggat gtggacacaa tttgtaagtc     1020

tgtgatcaaa acagggcgac tgctaatcag tcacgaggct cccttgacag gcggctttgc     1080

atcggaaatc agctctacag ttcaggagga atgtttcttg aacctagagg ctcctatatc     1140

aagagtatgt ggttatgaca caccatttcc tcacattttt gaaccattct acatcccaga     1200

caaatggaag tgttatgatg cccttcgaaa aatgatcaac tattgaccat ataggtaggt     1260

atgcatcttg agaaagctac tatgtgcccc tgacattaac gtactgttaa ccaagacaca     1320

gcaatcatca gtgttttgat ggtaacaaac tttgatggta aagttggtaa aaggcaactt     1380

tcagaagaaa ataatgtgct ttagaaaaaa aattcaaatt tatagtagta tatttacatt     1440

tttgttgttg ttgttgttct gagatggagt ctcactctgt cgcccaggct agactgcagt     1500

ggtgcaatct cagctcactg caacctcccc cctacccctg agttcaagcg attctcctgc     1560

ctcagcctgc tgagtagttg ggattacagg cgcccaccac catgcccagc taatttttgt     1620

gtttttattg gaggtggggt gtcactatgt tggctcagct gatttcaaat tcctgacctc     1680

aagtgatcca cctgccttag cctcccaaag tgctgggatt acaggcatga gccactgcac     1740

ctggctatat ttacatttaa tagaaacata tctagcatat gtatatgtga tttttttttt     1800

ttttttgaga ccgagtctca ctctgtcacc aggctggagt gcagtggtgc gatcttggct     1860

catggcaacc tctgcctccc aggttcaagc gattgtcctg cctcagtctc ctgagtagct     1920

gggactacag gtgtgcacca acatgcccag ctaatttttt atatttttag tagagacggg     1980

gtttcaccat gttggccagg atggtctcga tctcttgacc ttgtgttcca cccgccttgg     2040

cctcccaaag tgctggaatt acaggcatga gccaccgcgc ctggcctgta tatgtgattt     2100

ctaaaaaata gatgcatgca tatgttaaca ttgaatagtc aatcactaga tgaagatgct     2160

ctctaccatg gtttagattg caagtgtact ttataccatt gtttcaactt caacctttat     2220

ttttgtatat attttttcag ctacttaaac tgttcatgaa taggcgtact ttctgtattt     2280

aaaaatggcc cctcaagcac cgttaattta cattccagtt atttacatga taattcatga     2340

cattctgaaa cttgcctgta tattatctga aaaatggatt tcttgagcaa aagatctgtt     2400

tattgtatgt aaggaaaaat tttacctgaa aacaaacaaa caaaccctaa aactcagcac     2460

cactaccatt tccagaagct tttttaacaa gtgaatattt tttacataat ggataataaa     2520

tggtatttat tcatcatgat tttctaagta atgcttatca gccccttcag tggtgttatt     2580

ctaacaaaat gaatacatta caaattatta agttagcttt tcagagtttt aatatagaag     2640

ttactagcac tgacacactg attttgaaat gtttcaaaat gagtagatat gattagatcc     2700

tttacctttt aatatctagt ttttccaaaa atgatagtaa tatcttttga agaactatgc     2760

tttttcaaaa gcaaaatcaa ctctgtataa tagcacattc tctacttttt aaagatcaga     2820

aatgctagaa ttcttgactt ttgtgtatgg gtagtaaatc tagctcactg aaaatcagag     2880

tgaaacgcct ttacatttgt gcggatagag aagttaactc tccctcatat gtcactgtgc     2940

taccataatc cctacatttt ctgtctgttc tagtctaaga atattgttat agatggaagt     3000

taggaccatt agcccacaga tgcatgtatt ctctcagaca taccggtgta gatgctatat     3060

ttctgatgtc ttcttaatgt ctgtgaaagc aactggcatc tacaataaat cacacttaga     3120

gctggttaga ggactccttc acttttgttg tccatgtggt tcccttccgt ggaccagccg     3180

taataaagag ccaaggtagt gatggtggcc acgtgcctcg ttgctatttt taaagtaata     3240

ttcagatgtg gttttaaatt tagattatgt attccttttg aaacataaga aaaacattta     3300

aacctatgct gaaaatacga taaaagaaaa acaactccaa tatgctaaaa gttaaatatg     3360

gtatttaaga aaatagtcat gtatgcaatt gagaaagtct ataatttatt ttacagaaaa     3420

gctggaagat tatgactaga tatggaaata ttttttctga attttttttt atatttcctc     3480

cgacttacct ctttttgaaa agagagtttt tattaagtga accatcacga tattggctga     3540

aaagttctac attctattat tgtattgtaa cacacatgta ttgatgattt tcattaagag     3600

tttcagatta actttgaaaa atattccaca tggtaatctt ataaattctg tttaattaca     3660

tctgtaaata ttatgtgtgt gatagtattc aataaagtaa aatcaaattg tc             3712


<210>  1094
<211>  1427
<212>  DNA
<213>  homo sapiens

<400>  1094
atctccttcc gtcggtccgc tcagaatcag ctgtcctctc agactgtgtg ggtggtttcc       60

ccggccgcag ctccgtacgg gcttggattg ctgggcctcg gtgcacccca gcctccccca      120

ctcgggttct gagcttgagc tggcggctct ttaactctgc ttcactgttg ctcttggcaa      180

catccacttc cgggagcgag tgccgtttcc cccgctcacc gcgggctagg gagcgtggga      240

ttccggactg tgagcggctg ttagtgcgtc gcagctgctg gcgatccggc gaccctcggc      300

cggcaggacc cgcgggccac gcagccgggg ccttctcaac gcctcagtac ctcggcggga      360

ccgccatggt tctgctgcac gtgaagcggg gcgacgagag ccagttcctg ctgcaggcgc      420

ctgggagtac cgagctggag gagctcacgg tgcaggtggc ccgggtctat aatgggcggc      480

tcaaggtgca gcgcctctgc tcagaaatgg aagaattagc cgaacatggc atatttctcc      540

ctcctaatat gcaaggactg accgatgatc agattgaaga attgaaattg aaggatgaat      600

ggggtgaaaa atgcgtaccc agcggaggtg cagtgtttaa aaaggatgat attggacgaa      660

ggaatgggca agctccaaat gagaagatga agcaagtgtt aaagaagact atagaagaag      720

ccaaagcaat aatatctaag aaacaagtgg aagccggtgt ctgtgttacc atggagatgg      780

tgaaagatgc cttggaccag cttcgaggcg cggtgatgat tgtttacccc atggggttgc      840

caccgtatga tcccatccgc atggagtttg aaaataagga agacttgtcg ggaacacagg      900

cagggctcaa cgtcattaaa gaggcagagg cgcagctgtg gtgggcagcc aaggagctga      960

gaagaacgaa gaagctttca gactacgtgg ggaagaatga aaaaaccaaa attatcgcca     1020

agattcagca aaggggacag ggagctccag cccgagagcc tattattagc agtgaggagc     1080

agaagcagct gatgctgtac tatcacagaa gacaagagga gctcaagaga ttggaagaaa     1140

atgatgatga tgcctattta aactcaccat gggcggataa cactgctttg aaaagacatt     1200

ttcatggagt gaaagacata aagtggagac caagatgaag ttcaccagct gatgacactt     1260

ccaaagagat tagctcacct ttctcctagg caattataat ttaaaaaaaa aaaaaaggcc     1320

acttactgcc ctctgtaaaa gatgttaaca tttctagttt tcttttagtg tgaattttta     1380

aaatagcagt tattcaaggt tttagaactt aataaatacc tagtcag                   1427


<210>  1095
<211>  3672
<212>  DNA
<213>  homo sapiens

<400>  1095
gcactcagca ggttgggctg cggcggcggc ggctggggaa gccgaagcgc cgcgcgtgag       60

agatcccaga tacgtctgcg gttccggctc cgccaccctc cgcctttctc ccgcaggtct      120

tggagccggg tgaggaagaa gggaacggcc ctagccttgg gaagccaaag cacacccctg      180

gctcctgccg acaccgccct ccttcccttc ccagccgcgg gcctcgctcg gtgctcggct      240

actctgccgg gaggcggcgg cggctgccag tctgtggaga gtcctgctgc cctccagccg      300

ggctcctcca ccggcccttg caggggcgca gagagctcgg cgcccgccct tccgctcgcc      360

tttttcgtca gccggctgga gcagcatcgg tccgggaggt ctctgggctg aggcggcgac      420

agctcctcta gttccaccat gtccgcgggc ggagacttcg ggaatccgct gaggaaattc      480

aagctggtgt tcctggggga gcaaagcgtt gcaaagacat ctttgatcac cagattcagg      540

tatgacagtt ttgacaacac ctatcaggca ataattggca ttgacttttt atcaaaaact      600

atgtacttgg aggatggaac aatcgggctt cggctgtggg atacggcggg tcaggaacgt      660

ctccgtagcc tcattcccag gtacatccgt gattctgctg cagctgtagt agtttacgat      720

atcacaaatg ttaactcatt ccagcaaact acaaagtgga ttgatgatgt cagaacagaa      780

ggaggaagtg atgttatcat cacgctagta ggaaataaaa cagatcttgc tgacaagagg      840

caagtgtcaa ttgaggaggg agagaggaaa gccaaagggc tgaatgttac gtttattgaa      900

actagggcaa aagctggata caatgtaaag cagctctttc gacgtgtagc agcagctttg      960

ccgggaatgg aaagcacaca ggacggaagc agagaagaca tgagtgacat aaaactggaa     1020

aagcctcagg agcaaacagt cagcgaaggg ggttgttcct gctactctcc catgtcatct     1080

tcaacccttc ctcagaagcc cccttactct ttcattgact gcagtgtgaa tattggcttg     1140

aaccttttcc cttcattaat aacgttttgc aattcatcat tgctgcctgt ctcgtggaga     1200

tgatctatta gcttgacaag cacaaaaaaa gtcagcgtct tcattattta tattttacaa     1260

aaagccaaac tatttcagcg tattccagtg ataactttaa aaattagata cattttctta     1320

acattttttt tcttttttaa tgttatgata atgtacttca aaatgatgga aatctcaaca     1380

gtatgagtat ggcttggtta acgagcagta tgttcacagc ctgctttatc tctccttgct     1440

cttctcacct ctcccttacc ccgttcccta tttccgtgtt cttacctagc ctccccccac     1500

ttcctcaaaa caaacaagag atggcaaagc agcagtccga ccaagcccac tggaattatc     1560

ctttaatttt acagatacca cttgctgtag gctgtggacc aagatgtcca gaattattct     1620

tgagcactga tataaattac ttagatcctc tttgaggtca gaattcagcg atcacggtag     1680

gcagtgcttg aatgagaaaa gcctcctggt gcatcttcaa aatgagtcct aaagaacata     1740

ctgagtactt ataagtagca gaacataaaa tgtatttctg actaaaacaa atggtccttt     1800

cacatgtgct ttattagact ctgggagaga aaattaacca agtgcttcag aacaggtttt     1860

tagtatttaa ttcttcatgg taagataatg acgttctaat gaactatttc tcccaaggtt     1920

ttaaaattgt caagagttat tctgtttgtt taaaaaataa gaaacctctt taagcaatag     1980

attttgcttg ggttttcttt ttttaaaaaa taatactatg caggcaagac accataaaag     2040

tttaattcct tacagaagaa ccagtggaag aatttaaatt tggcactacg atcaaaacta     2100

ctgaattagc agaaataacg atatctaaag cttaccaaca aaagaaccct cagcagaaga     2160

gcaaaaactt tgctcaggac atttgaggtc aaattgaaga tggaaaccgg aaaccatttt     2220

cttgtaagcc cctagaggca gatcaggtaa agcatacata gtagagggaa aggagagaat     2280

ggaaataaaa ctgaatatta tgcagattta tgccttattt tttagcattt ttttaaggtt     2340

gggtctttca ggctggtttt cgtttgtatg agatctgtat agtttaatta actaatgatt     2400

tagttttata tttaagctac gattaatctt ttttctttgg tgatatttct ttgctttttt     2460

tttaacaact ttcaattttt agatgtttcg ttgaatctat ttagagcttc accatggcaa     2520

tatgtatttc ccttgaaaca ctgcaaacaa atatactagg agtgtgccct tttaatcttc     2580

actagttatt gtgagattgc tgtgtaagct aataaacaca tttgtaaata cattgtttgc     2640

aggaagaaaa cttcgagtta taggtcagga aaagcctgct gaatttatgt tgtaaacgtt     2700

acttaacaca gtataaagat gaaaagacaa caaaaatatc ttcatacttc ctcatcccct     2760

cattgcaaca aaaccttaaa ctgggagaac cttagtcccc tctctttcct cttcctcctc     2820

cacttcccac ttattgtcac cttgtaatat tcagagagca cttggattat ggatctgaat     2880

agagaaatgc ttacagataa tcattagccc acataccagt aacttacact taaagatggg     2940

atggagttat aaagtgcttt tataatacaa tataattgct aaaggcaagg gttgactctg     3000

ttttattttg acatggcatg tcctgaaata aatattgatt cactgtggca gatgggtcat     3060

actctttatt tggaagaagt tgtgacttct gacatggggg tgattgcctt cctacactgt     3120

tgcatttgat tctttttatg tattttttaa aaagtaagca gttatactgc ttttaatatt     3180

gattggtctt tttatttggc ttggagttct tcaaagcagt gaagtgtgtt catagtccag     3240

attttttttt agtaaacaca attttgctgc caaaaatata taaataaaac acaaaacaaa     3300

aattaaaaaa tgttgaaaat attagaccat ctcccttttt accaccttcc ctttttacct     3360

tttactgcca tttacatcca cacatccaca cacacaatgc tatgctatgt ttaatagcat     3420

ttccctgatt accaatatta ggcattatat attgtctatt catgttttca tattttgtat     3480

aatgtctata tcctttgttc attaaattgt gttatttgta ttattcttta taattcttta     3540

acacattgct gtttatatgt tggttatatt ttacattttc ttctagttta tgggaagtct     3600

ttttcttttc ctaagacaat ctattgataa atataagcta tgaatattaa agttataatt     3660

aaagttaaaa aa                                                         3672


<210>  1096
<211>  3705
<212>  DNA
<213>  homo sapiens

<400>  1096
tttggcatcc aggagaccgt gcgggagacc gacgctgagc gccggcctcg ccctcggcgg       60

cccctccctc ctccttaccc cgcctccccc ggcccgcccc tccctccccg gaggagcagt      120

ctctccgcgc gtctcccgga gctttctcca ttgtctctgc ctttacaaca ggttcgggcg      180

gcggggaaga cgggggggtg cggggccgcc ccagcccggg ctttcttggg gccgcccccc      240

ttctaccggg tgtgcgagtc tttggctgct tttattcggc tcgggagcta attccccgac      300

ggagccgcgc cggggcgagt ccgacccctc cctccgggcc ccctccgggc cgcgctgccg      360

cctcggccct gcgtgtggga atgatgtgcg cattggaggg tctaagttct tcacgcgcct      420

ggggaggcct cccttttctt tcttaggcaa ccaaagcgta ttaatcctac tgatcagtaa      480

atccgaggca gcagcaggag agacaaacgt tattttcccg cttgattcca agaacctctt      540

cgatttttat ttttattttt aaagagggag acgatggact gagctgatcc gcaccatgga      600

gtctcgggtc ttactgagaa cattctgttt gatcttcggt ctcggagcag tttgggggct      660

tggtgtggac ccttccctac agattgacgt cttaacagag ttagaacttg gggagtccac      720

gaccggagtg cgtcaggtcc cggggctgca taatgggacg aaagcctttc tctttcaaga      780

tactcccaga agcataaaag catccactgc tacagctgaa cagttttttc agaagctgag      840

aaataaacat gaatttacta ttttggtgac cctaaaacag acccacttaa attcaggagt      900

tattctctca attcaccact tggatcacag gtacctggaa ctggaaagta gtggccatcg      960

gaatgaagtc agactgcatt accgctcagg cagtcaccgc cctcacacag aagtgtttcc     1020

ttacattttg gctgatgaca agtggcacaa gctctcctta gccatcagtg cttcccattt     1080

gattttacac attgactgca ataaaattta tgaaagggta gtagaaaagc cctccacaga     1140

cttgcctcta ggcacaacat tttggctagg acagagaaat aatgcgcatg gatattttaa     1200

gggtataatg caagatgtcc aattacttgt catgccccag ggatttattg ctcagtgccc     1260

agatcttaat cgcacctgtc caacttgcaa tgacttccat ggacttgtgc agaaaatcat     1320

ggagctacag gatattttag ccaaaacatc agccaagctg tctcgagctg aacagcgaat     1380

gaatagattg gatcagtgct attgtgaaag gacttgcacc atgaagggaa ccacctaccg     1440

agaatttgag tcctggatag acggctgtaa gaactgcaca tgcctgaatg gaaccatcca     1500

gtgtgaaact ctaatctgcc caaatcctga ctgcccactt aagtcggctc ttgcgtatgt     1560

ggatggcaaa tgctgtaagg aatgcaaatc gatatgccaa tttcaaggac gaacctactt     1620

tgaaggagaa agaaatacag tctattcctc ttctggagta tgtgttctct atgagtgcaa     1680

ggaccagacc atgaaacttg ttgagagttc aggctgtcca gctttggatt gtccagagtc     1740

tcatcagata accttgtctc acagctgttg caaagtttgt aaaggttatg acttttgttc     1800

tgaaaggcat aactgcatgg agaattccat ctgcagaaat ctgaatgaca gggctgtttg     1860

tagctgtcga gatggtttta gggctcttcg agaggataat gcctactgtg aagacatcga     1920

tgagtgtgct gaagggcgcc attactgtcg tgaaaataca atgtgtgtca acaccccggg     1980

ttcttttatg tgcatctgca aaactggata catcagaatt gatgattatt catgtacaga     2040

acatgatgag tgtatcacaa atcagcacaa ctgtgatgaa aatgctttat gcttcaacac     2100

tgttggagga cacaactgtg tttgcaagcc gggctataca gggaatggaa cgacatgcaa     2160

agcattttgc aaagatggct gtaggaatgg aggagcctgt attgccgcta atgtgtgtgc     2220

ctgcccacaa ggcttcactg gacccagctg tgaaacggac attgatgaat gctctgatgg     2280

ttttgttcaa tgtgacagtc gtgctaattg cattaacctg cctggatggt accactgtga     2340

gtgcagagat ggctaccatg acaatgggat gttttcacca agtggagaat cgtgtgaaga     2400

tattgatgag tgtgggaccg ggaggcacag ctgtgccaat gataccattt gcttcaattt     2460

ggatggcgga tatgattgtc gatgtcctca tggaaagaat tgcacagggg actgcatcca     2520

tgatggaaaa gttaagcaca atggtcagat ttgggtgttg gaaaatgaca ggtgctctgt     2580

gtgctcatgt cagaatggat tcgttatgtg tcgacggatg gtctgtgact gtgagaatcc     2640

cacagttgat cttttttgct gccctgaatg tgacccaagg cttagtagtc agtgcctcca     2700

tcaaaatggg gaaactttgt ataacagtgg tgacacctgg gtccagaatt gtcaacagtg     2760

ccgctgcttg caaggggaag ttgattgttg gcccctgcct tgcccagatg tggagtgtga     2820

attcagcatt ctcccagaga atgagtgctg cccgcgctgt gtcacagacc cttgccaggc     2880

tgacaccatc cgcaatgaca tcaccaagac ttgcctggac gaaatgaatg tggttcgctt     2940

caccgggtcc tcttggatca aacatggcac tgagtgtact ctctgccagt gcaagaatgg     3000

ccacatctgt tgctcagtgg atccacagtg ccttcaggaa ctgtgaagtt aactgtctca     3060

tgggagattt ctgttaaaag aatgttcttt cattaaaaga ccaaaaagaa gttaaaactt     3120

aaattgggtg atttgtgggc agctaaatgc agctttgtta atagctgagt gaactttcaa     3180

ttatgaaatt tgtggagctt gacaaaatca caaaaggaaa attactgggg caaaattaga     3240

cctcaagtct gcctctactg tgtctcacat caccatgtag aagaatgggc gtacagtata     3300

taccgtgaca tcctgaaccc tggatagaaa gcctgagccc attggatctg tgaaagcctc     3360

tagcttcact ggtgcagaaa attttcctct agatcagaat cttcaagaat cagttaggtt     3420

cctcactgca agaaataaaa tgtcaggcag tgaatgaatt atattttcag aagtaaagca     3480

aagaagctat aacatgttat gtacagtaca ctctgaaaag aaatctgaaa caagttattg     3540

taatgataaa aataatgcac aggcatggtt acttaatatt ttctaacagg aaaagtcatc     3600

cctatttcct tgttttactg cacttaatat tatttggttg aatttgttca gtataagctc     3660

gttcttgtgc aaaattaaat aaatatttct cttaccttat aacac                     3705


<210>  1097
<211>  9894
<212>  DNA
<213>  homo sapiens

<400>  1097
acaagctctc catgtgagct gacaggcgag tggaaacccc tcgagtcacg ctgcccggcg       60

gcggagggag cgctcgcccg cagtggcaac agctgcacca ccgtccccgt cgctctgcct      120

tcctcttctg cagcctctgc tcttctgatt acctccctcc cccgtccttt ggtgattttt      180

ttttttcaag aaggagaggg cggggtaggt gtccgttccc tcccctcttc cccctccttt      240

gccttcttgg tttgaatttc ctcccccggc gttgcactgg cacacagtgc aagaggcaat      300

acccgcacgg agggagaacg aaggctgaga ctcccctgcc gctccaagcc cggaagaact      360

ggagcctgga ggggggtgag gggagaagag gaagcgggag gggcttggct tcctcgcgta      420

tttgaggaca gcccatctcc cttcaagaac cctacggaga gtcggactgc atctccgcag      480

cgagctcttg gagcgccgcc ggccgggagg cgaaggatgc aggcggctcc gcgcgccggc      540

tgcggggcag cgctcctgct gtggattgtc agcagctgcc tctgcagagc ctggacggct      600

ccctccacgt cccaaaaatg tgatgagcca cttgtctctg gactccccca tgtggctttc      660

agcagctcct cctccatctc tggtagctat tctcccggct atgccaagat aaacaagaga      720

ggaggtgctg ggggatggtc tccatcagac agcgaccatt atcaatggct tcaggttgac      780

tttggcaatc ggaagcagat cagtgccatt gcaacccaag gaaggtatag cagctcagat      840

tgggtgaccc aataccggat gctctacagc gacacaggga gaaactggaa accctatcat      900

caagatggga atatctgggc atttcccgga aacattaact ctgacggtgt ggtccggcac      960

gaattacagc atccgattat tgcccgctat gtgcgcatag tgcctctgga ttggaatgga     1020

gaaggtcgca ttggactcag aattgaagtt tatggctgtt cttactgggc tgatgttatc     1080

aactttgatg gccatgttgt attaccatat agattcagaa acaagaagat gaaaacactg     1140

aaagatgtca ttgccttgaa ctttaagacg tctgaaagtg aaggagtaat cctgcacgga     1200

gaaggacagc aaggagatta cattaccttg gaactgaaaa aagccaagct ggtcctcagt     1260

ttaaacttag gaagcaacca gcttggcccc atatatggcc acacatcagt gatgacagga     1320

agtttgctgg atgaccacca ctggcactct gtggtcattg agcgccaggg gcggagcatt     1380

aacctcactc tggacaggag catgcagcac ttccgtacca atggagagtt tgactacctg     1440

gacttggact atgagataac ctttggaggc atccctttct ctggcaagcc cagctccagc     1500

agtagaaaga atttcaaagg ctgcatggaa agcatcaact acaatggcgt caacattact     1560

gatcttgcca gaaggaagaa attagagccc tcaaatgtgg gaaatttgag cttttcttgt     1620

gtggaaccct atacggtgcc tgtctttttc aacgctacaa gttacctgga ggtgcccgga     1680

cggcttaacc aggacctgtt ctcagtcagt ttccagttta ggacatggaa ccccaatggt     1740

ctcctggtct tcagtcactt tgcggataat ttgggcaatg tggagattga cctcactgaa     1800

agcaaagtgg gtgttcacat caacatcaca cagaccaaga tgagccaaat cgatatttcc     1860

tcaggttctg ggttgaatga tggacagtgg cacgaggttc gcttcctagc caaggaaaat     1920

tttgctattc tcaccatcga tggagatgaa gcatcagcag ttcgaactaa tagtcccctt     1980

caagttaaaa ctggcgagaa gtactttttt ggaggttttc tgaaccagat gaataactca     2040

agtcactctg tccttcagcc ttcattccaa ggatgcatgc agctcattca agtggacgat     2100

caacttgtaa atttatacga agtggcacaa aggaagccgg gaagtttcgc gaatgtcagc     2160

attgacatgt gtgcgatcat agacagatgt gtgcccaatc actgtgagca tggtggaaag     2220

tgctcgcaaa catgggacag cttcaaatgc acttgtgatg agacaggata cagtggggcc     2280

acctgccaca actctatcta cgagccttcc tgtgaagcct acaaacacct aggacagaca     2340

tcaaattatt actggataga tcctgatggc agcggacctc tggggcctct gaaagtttac     2400

tgcaacatga cagaggacaa agtgtggacc atagtgtctc atgacttgca gatgcagacg     2460

cctgtggtcg gctacaaccc agaaaaatac tcagtgacac agctcgttta cagcgcctcc     2520

atggaccaga taagtgccat cactgacagt gccgagtact gcgagcagta tgtctcctat     2580

ttctgcaaga tgtcaagatt gttgaacacc ccagatggaa gcccttacac ttggtgggtt     2640

ggcaaagcca acgagaagca ctactactgg ggaggctctg ggcctggaat ccagaaatgt     2700

gcctgcggca tcgaacgcaa ctgcacagat cccaagtact actgtaactg cgacgcggac     2760

tacaagcaat ggaggaagga tgctggtttc ttatcataca aagatcacct gccagtgagc     2820

caagtggtgg ttggagatac tgaccgtcaa ggctcagaag ccaaattgag cgtaggtcct     2880

ctgcgctgcc aaggagacag gaattattgg aatgccgcct ctttcccaaa cccatcctcc     2940

tacctgcact tctctacttt ccaaggggaa actagcgctg acatttcttt ctacttcaaa     3000

acattaaccc cctggggagt gtttcttgaa aatatgggaa aggaagattt catcaagctg     3060

gagctgaagt ctgccacaga agtgtccttt tcatttgatg tgggaaatgg gccagtagag     3120

attgtagtga ggtcaccaac ccctctcaac gatgaccagt ggcaccgggt cactgcagag     3180

aggaatgtca agcaggccag cctacaggtg gaccggctac cgcagcagat ccgcaaggcc     3240

ccaacagaag gccacacccg cctggagctc tacagccagt tatttgtggg tggtgctggg     3300

ggccagcagg gcttcctggg ctgcatccgc tccttgagga tgaatggggt gacacttgac     3360

ctggaggaaa gagcaaaggt cacatctggg ttcatatccg gatgctcggg ccattgcacc     3420

agctatggaa caaactgtga aaatggaggc aaatgcctag agagatacca cggttactcc     3480

tgcgattgct ctaatactgc atatgatgga acattttgca acaaagatgt tggtgcattt     3540

tttgaagaag ggatgtggct acgatataac tttcaggcac cagcaacaaa tgccagagac     3600

tccagcagca gagtagacaa cgctcccgac cagcagaact cccacccgga cctggcacag     3660

gaggagatcc gcttcagctt cagcaccacc aaggcgccct gcattctcct ctacatcagc     3720

tccttcacca cagacttctt ggcagtcctc gtcaaaccca ctggaagctt acagattcga     3780

tacaacctgg gtggcacccg agagccatac aatattgacg tagaccacag gaacatggcc     3840

aatggacagc cccacagtgt caacatcacc cgccacgaga agaccatctt tctcaagctc     3900

gatcattatc cttctgtgag ttaccatctg ccaagttcat ccgacaccct cttcaattct     3960

cccaagtcgc tctttctggg aaaagttata gaaacaggga aaattgacca agagattcac     4020

aaatacaaca ccccaggatt cactggttgc ctctccagag tccagttcaa ccagatcgcc     4080

cctctcaagg ccgccttgag gcagacaaac gcctcggctc acgtccacat ccagggcgag     4140

ctggtggagt ccaactgcgg ggcctcgccg ctgaccctct cccccatgtc gtccgccacc     4200

gacccctggc acctggatca cctggattca gccagtgcgg attttccata taatccagga     4260

caaggccaag ctataagaaa tggagtcaac agaaactcgg ctatcattgg aggcgtcatt     4320

gctgtggtga ttttcaccat cctgtgcacc ctggtcttcc tgatccggta catgttccgc     4380

cacaagggca cctaccatac caacgaagca aagggggcgg agtcggcaga gagcgcggac     4440

gccgccatca tgaacaacga ccccaacttc acagagacca ttgatgaaag caaaaaggaa     4500

tggctcattt gaggggtggc tacttggcta tgggataggg aggagggaat tactagggag     4560

gagagaaagg gacaaaagca ccctgcttca tactcttgag cacatcctta aaatatcagc     4620

acaagttggg ggaggcaggc aatggaatat aatggaatat tcttgagact gatcacaaaa     4680

aaaaaaacct ttttaatatt tctttatagc tgagttttcc cttctgtatc aaaacaaaat     4740

aatacaaaaa atgcttttag agtttaagca atggttgaaa tttgtaggta ctatctgtct     4800

tattttgtgt gtgtttagag gtgttctaaa gacccgtggt aacagggcaa gttttctacg     4860

tttttaagag cccttagaac gtgggtattt tttttcttga gaaaagctaa tgcacctaca     4920

gatggccccc aacattctct tccttttgct tctagtcaac cttaatgggc tgttacagaa     4980

actagttcgt gtttatatac tatttccttt gatgtcctat aagtcggaaa agaaaggggc     5040

aaagagaacc tattatttgc cagtttttaa gcagagctca atctatgcca gctctctggc     5100

atctggggtt cctgactgat accagcagtt gaaggaagag agtgcatggc acctggtgtg     5160

taacgacaca atcagcacaa ctggagagag gcattaaaga accagggaag gtagtttgat     5220

ttttcattga attctacaag ctaatattgt tccacgtatg tagtcttaga ccaatagctg     5280

taactatcag ctgcaatacc atggtgacca gctgttacaa aagatttttt cctgttttat     5340

ctgaaacata ctggatttat atatgtataa gcgcctcaat ggggaattag agccagatgt     5400

tatgatttgt ttgctctttt tcttttatag tttagttata gcaaaaatat ggataatttc     5460

tagtgaatgc ataaattagg ttgcgtttct tattttgctt taaatctctg gtagtttttc     5520

cacccctgtg acacaatcct aatagacagt gtcctgtaaa tggacacaac acaataaagt     5580

caagttatta ttgctgttac tctggatgat atggaaaaca ctgccatatt ttaaatcaac     5640

tactccacgt gtttttccat ccaatcacac tgctgtgatt cagggatctt tcttctaaga     5700

cggacacatt tgaacctcag gttcatcaca aacctggtac ctgttgcttc ccagaggatg     5760

gagaagtgta gttaatcaca cctcttagtt taatctgaaa tcttgaccca gttatttaac     5820

aaataaatac ctcattgatt atatttaaaa gtaatacact tcctgtaaac aaatggggac     5880

aatgcatcca aaaaatcttt ttaaacagat tacacaaaaa ttatttccag aaaggctacc     5940

atttatcatc attatatttc aagcctctta tacttaataa gcactttcta aaaagtcttg     6000

agatcccacc attctgagga attcaatatg atcacttttt ccttctttgc ctgggagagg     6060

ttaagaggag gtttcgaagg tatagatgct attgttctga tggcccggct gaataaaatg     6120

gaaattctag tttgttagaa ttatgcattc tttttcaaga ttctcagtgt gcctaactta     6180

ttggagcaca tcagtttctt gggtaatgga aaacattacc tagagttgcc agtggcacat     6240

tacaccagta cagagcacat tccaaaggag acattggacc agttaattcc catacaagtc     6300

aaggtaacag aacaaaaggg aatcctgatg cccttttacc attgctggtt gagctcaggc     6360

actgtcatgg acacccttaa ttttaaaagg ttttaatcat tcttctataa aatacattta     6420

aaatggaaaa atacttaata tcactaaata tcagaacaat gtaacattta caaatgacat     6480

attgaaagca aaggctgttt tatttagcca agatgattac cattaggagt tactttatgt     6540

attgttgaaa gcaaatttta aacatgatgt tttagaagtg tttctgattt ttaaacctgg     6600

tttacaggta ttacttctgc acttaccaaa taatgccaga tggaaattta ttatttcttg     6660

caattcccat gatagctctg ttctttatgc attgtctcaa cactttccct tttttcccaa     6720

aatgagtaga gaattaaagc cacccaaaac agcttctgct actaaaatgt tctcatcctt     6780

tctcctccct ctccttttcc tgccacaaaa ggtgaaaaat gagatccaat cctctcacca     6840

aaatttcaaa cctaggacac tggaatgact gcagggatca gtggttctcc catatcacca     6900

tcaattaaga catataggac actgtcttcc ttcaagaggg ttacaatgtg gccatcagac     6960

aggaaaccaa acggtggata aagtattaag taactaagtg ccaaataaat gctggaaatc     7020

ttgacctctc cttgggatta tgggtgtaac aaaaatccct acatctgttt atgaaggcca     7080

tattcagtac attttaaatg gtaaataatc tgtttatgtg aagaaaaaga attaagtctt     7140

tcttccaact ctctccttgg atagcctagc acagtgcagc ctccataacc atgacattcc     7200

cgcccaagct ctcagtgcct aatcctgctt tgtcattcac atctcacaaa atcttgacat     7260

cttacattcc aatacattat caagcaagca caagtatgct ggtagtagcc tctttaaata     7320

atatgtatag acaacaacaa cgacaaaaaa tagactgttt taaagtttca gggaaagttg     7380

gtggctgatt taaagttgtg caggaaacat cttctgtgta tgaagcaaat gtcgatgttt     7440

tgaaaaaagc taggagatga ctttgaatga atgcaaggtt agtgagatcc taagctctca     7500

aaatagcata ttccctagag ctcaagaaag ctggtccagg aggttgaaaa agctattttg     7560

ttgttaaatt attttctggc ccttcttaat atttaaaaat gtatttcccc ttgtggcttt     7620

caaccacctg ctcaaaaaaa gagacttgtt acatgaaagt tttcattaaa gagctgaaaa     7680

caagaattta gagagccatt cctagaaaat gtcctactgc cctgcatttg acaaacaagc     7740

atcctttact aacaagagca ggaattcaga ggcacaagaa aaagcattgg catgagccaa     7800

agagtctgtc ttaatgttac ttttgaaaat ctgctgagcg gccaccatat gcaggctgag     7860

agctgggcac aggcgaagcc attggaagca cttcaggaac aagcacacag ctgtgggact     7920

tgaacatgca agtgttcagg ttgtgtcaag aagcttttct ttccttctat gatggaatct     7980

gttcttttct atcctacttt tttctctctt cctctcctca ccacattata ccctgctctt     8040

acgcagtaaa cgttttaatg gcccgtttat gtctcatgcc tccaaacaac actgaatttg     8100

aaacccccca ttttttcttt tcaccaccct gttgagcaat tttcccaaaa aaagggcagc     8160

aattattaaa ttgaattcaa gtaagccagc caaagatagg tcctaaattg ctagtcccag     8220

tagaaccacc tgatcctaaa ccagtgcgaa acaaacagta acaatgtccc cagctgactt     8280

cagctaagaa ccaatggctc ctacccccgc cccgcttttt tttgttgttt tttgttttgt     8340

tttgagacgg agtcttgctc tgtcccccag gctggagtgc actggcgcaa tctcgggctc     8400

actgcaacct cctcctcctc ccacattgag gcgattctcc tgcctcagcc tcccaagtag     8460

ctgggattac aggcacccgc catcacaccc agctaatttt tttttttttt tgtattatta     8520

gtagaagcca ggtttcacca tgttggccag ggtggtctcg aactcctgac ctcaagtgat     8580

ccgtccacct cggccttgca aattgctggg attacaggtg tgagccaccg tgccgagcca     8640

gccccatttt ttaaatgatg ttttggttaa gagtggacca tgagaattag ctgacagcat     8700

cccctttctc tctccctgcc ttggtgggac cctccctgtg tgaccttggt caagtcctcg     8760

aacttttgtc ccgtatttaa gatggagctg ttttacctac ttcataagac agttgcgagg     8820

tgccattgat tcttgactgc aaaatacctt gaaaccctta tataaagact gaagtcaacg     8880

gagcctagtg aaagacttac tttgtggctt gtggttgaaa gtcacatcaa aagacaaatg     8940

tggccacgtt caggaattgg agacttactg gcatggctct acagctgctc agttattaat     9000

catgcagact aacctgtcaa cactgggaga tgcaacatag caaaaggaca gagaaattag     9060

aattttttgt gcagaaagcc ctaaattccc acctgaatgt aacttacagc tcccttacct     9120

actctcacac atgccctcaa acatgctaga ttggcttata cataggccaa cacaaaatac     9180

aaacgtgacg tgttcatgta gcctagtggc tatatgccta ttctccatgt accctgcatg     9240

gtagtgctgc aaactttaaa gtacatttct ttcacagcag tatttttttt cataagtggc     9300

atataaatgt cattcaatga aatggggaaa tcacgttgag aagttggtct gtcatctccc     9360

attgagcaaa gactggcagg agataataaa aataaatatg ggcacacatg tattaatata     9420

cagcacgcat ttacaagttt attttccaga taaaattgtg ctataagaac agctctacca     9480

agacagtctg caccatttcc aagtctcagt taatttacag caactgctgc tttcggagat     9540

ggctgtgaaa atatggaagt tcctctcaag taggccaaga aacagttcta gattttacta     9600

agttttattt tgtcaggttt tttaaatttt ttcagtgagc gtggtgactg cagaggttag     9660

tgctgtgaaa agctgggcta aatattcttt ctgtaaagtc aaacaggatt ccatcccctg     9720

tgaaataaca caaaatttca ctctctaaaa gcaacagcat gtaaactaga atgaaagaag     9780

gaaattatgt acgtatgcct aatattcttt gtgaatgtct ttcatttaac taaaattata     9840

ttagaaacca gattgataaa taaaaaattc aaagtagttt taattatcct aaaa           9894


<210>  1098
<211>  9894
<212>  DNA
<213>  homo sapiens

<400>  1098
acaagctctc catgtgagct gacaggcgag tggaaacccc tcgagtcacg ctgcccggcg       60

gcggagggag cgctcgcccg cagtggcaac agctgcacca ccgtccccgt cgctctgcct      120

tcctcttctg cagcctctgc tcttctgatt acctccctcc cccgtccttt ggtgattttt      180

ttttttcaag aaggagaggg cggggtaggt gtccgttccc tcccctcttc cccctccttt      240

gccttcttgg tttgaatttc ctcccccggc gttgcactgg cacacagtgc aagaggcaat      300

acccgcacgg agggagaacg aaggctgaga ctcccctgcc gctccaagcc cggaagaact      360

ggagcctgga ggggggtgag gggagaagag gaagcgggag gggcttggct tcctcgcgta      420

tttgaggaca gcccatctcc cttcaagaac cctacggaga gtcggactgc atctccgcag      480

cgagctcttg gagcgccgcc ggccgggagg cgaaggatgc aggcggctcc gcgcgccggc      540

tgcggggcag cgctcctgct gtggattgtc agcagctgcc tctgcagagc ctggacggct      600

ccctccacgt cccaaaaatg tgatgagcca cttgtctctg gactccccca tgtggctttc      660

agcagctcct cctccatctc tggtagctat tctcccggct atgccaagat aaacaagaga      720

ggaggtgctg ggggatggtc tccatcagac agcgaccatt atcaatggct tcaggttgac      780

tttggcaatc ggaagcagat cagtgccatt gcaacccaag gaaggtatag cagctcagat      840

tgggtgaccc aataccggat gctctacagc gacacaggga gaaactggaa accctatcat      900

caagatggga atatctgggc atttcccgga aacattaact ctgacggtgt ggtccggcac      960

gaattacagc atccgattat tgcccgctat gtgcgcatag tgcctctgga ttggaatgga     1020

gaaggtcgca ttggactcag aattgaagtt tatggctgtt cttactgggc tgatgttatc     1080

aactttgatg gccatgttgt attaccatat agattcagaa acaagaagat gaaaacactg     1140

aaagatgtca ttgccttgaa ctttaagacg tctgaaagtg aaggagtaat cctgcacgga     1200

gaaggacagc aaggagatta cattaccttg gaactgaaaa aagccaagct ggtcctcagt     1260

ttaaacttag gaagcaacca gcttggcccc atatatggcc acacatcagt gatgacagga     1320

agtttgctgg atgaccacca ctggcactct gtggtcattg agcgccaggg gcggagcatt     1380

aacctcactc tggacaggag catgcagcac ttccgtacca atggagagtt tgactacctg     1440

gacttggact atgagataac ctttggaggc atccctttct ctggcaagcc cagctccagc     1500

agtagaaaga atttcaaagg ctgcatggaa agcatcaact acaatggcgt caacattact     1560

gatcttgcca gaaggaagaa attagagccc tcaaatgtgg gaaatttgag cttttcttgt     1620

gtggaaccct atacggtgcc tgtctttttc aacgctacaa gttacctgga ggtgcccgga     1680

cggcttaacc aggacctgtt ctcagtcagt ttccagttta ggacatggaa ccccaatggt     1740

ctcctggtct tcagtcactt tgcggataat ttgggcaatg tggagattga cctcactgaa     1800

agcaaagtgg gtgttcacat caacatcaca cagaccaaga tgagccaaat cgatatttcc     1860

tcaggttctg ggttgaatga tggacagtgg cacgaggttc gcttcctagc caaggaaaat     1920

tttgctattc tcaccatcga tggagatgaa gcatcagcag ttcgaactaa tagtcccctt     1980

caagttaaaa ctggcgagaa gtactttttt ggaggttttc tgaaccagat gaataactca     2040

agtcactctg tccttcagcc ttcattccaa ggatgcatgc agctcattca agtggacgat     2100

caacttgtaa atttatacga agtggcacaa aggaagccgg gaagtttcgc gaatgtcagc     2160

attgacatgt gtgcgatcat agacagatgt gtgcccaatc actgtgagca tggtggaaag     2220

tgctcgcaaa catgggacag cttcaaatgc acttgtgatg agacaggata cagtggggcc     2280

acctgccaca actctatcta cgagccttcc tgtgaagcct acaaacacct aggacagaca     2340

tcaaattatt actggataga tcctgatggc agcggacctc tggggcctct gaaagtttac     2400

tgcaacatga cagaggacaa agtgtggacc atagtgtctc atgacttgca gatgcagacg     2460

cctgtggtcg gctacaaccc agaaaaatac tcagtgacac agctcgttta cagcgcctcc     2520

atggaccaga taagtgccat cactgacagt gccgagtact gcgagcagta tgtctcctat     2580

ttctgcaaga tgtcaagatt gttgaacacc ccagatggaa gcccttacac ttggtgggtt     2640

ggcaaagcca acgagaagca ctactactgg ggaggctctg ggcctggaat ccagaaatgt     2700

gcctgcggca tcgaacgcaa ctgcacagat cccaagtact actgtaactg cgacgcggac     2760

tacaagcaat ggaggaagga tgctggtttc ttatcataca aagatcacct gccagtgagc     2820

caagtggtgg ttggagatac tgaccgtcaa ggctcagaag ccaaattgag cgtaggtcct     2880

ctgcgctgcc aaggagacag gaattattgg aatgccgcct ctttcccaaa cccatcctcc     2940

tacctgcact tctctacttt ccaaggggaa actagcgctg acatttcttt ctacttcaaa     3000

acattaaccc cctggggagt gtttcttgaa aatatgggaa aggaagattt catcaagctg     3060

gagctgaagt ctgccacaga agtgtccttt tcatttgatg tgggaaatgg gccagtagag     3120

attgtagtga ggtcaccaac ccctctcaac gatgaccagt ggcaccgggt cactgcagag     3180

aggaatgtca agcaggccag cctacaggtg gaccggctac cgcagcagat ccgcaaggcc     3240

ccaacagaag gccacacccg cctggagctc tacagccagt tatttgtggg tggtgctggg     3300

ggccagcagg gcttcctggg ctgcatccgc tccttgagga tgaatggggt gacacttgac     3360

ctggaggaaa gagcaaaggt cacatctggg ttcatatccg gatgctcggg ccattgcacc     3420

agctatggaa caaactgtga aaatggaggc aaatgcctag agagatacca cggttactcc     3480

tgcgattgct ctaatactgc atatgatgga acattttgca acaaagatgt tggtgcattt     3540

tttgaagaag ggatgtggct acgatataac tttcaggcac cagcaacaaa tgccagagac     3600

tccagcagca gagtagacaa cgctcccgac cagcagaact cccacccgga cctggcacag     3660

gaggagatcc gcttcagctt cagcaccacc aaggcgccct gcattctcct ctacatcagc     3720

tccttcacca cagacttctt ggcagtcctc gtcaaaccca ctggaagctt acagattcga     3780

tacaacctgg gtggcacccg agagccatac aatattgacg tagaccacag gaacatggcc     3840

aatggacagc cccacagtgt caacatcacc cgccacgaga agaccatctt tctcaagctc     3900

gatcattatc cttctgtgag ttaccatctg ccaagttcat ccgacaccct cttcaattct     3960

cccaagtcgc tctttctggg aaaagttata gaaacaggga aaattgacca agagattcac     4020

aaatacaaca ccccaggatt cactggttgc ctctccagag tccagttcaa ccagatcgcc     4080

cctctcaagg ccgccttgag gcagacaaac gcctcggctc acgtccacat ccagggcgag     4140

ctggtggagt ccaactgcgg ggcctcgccg ctgaccctct cccccatgtc gtccgccacc     4200

gacccctggc acctggatca cctggattca gccagtgcgg attttccata taatccagga     4260

caaggccaag ctataagaaa tggagtcaac agaaactcgg ctatcattgg aggcgtcatt     4320

gctgtggtga ttttcaccat cctgtgcacc ctggtcttcc tgatccggta catgttccgc     4380

cacaagggca cctaccatac caacgaagca aagggggcgg agtcggcaga gagcgcggac     4440

gccgccatca tgaacaacga ccccaacttc acagagacca ttgatgaaag caaaaaggaa     4500

tggctcattt gaggggtggc tacttggcta tgggataggg aggagggaat tactagggag     4560

gagagaaagg gacaaaagca ccctgcttca tactcttgag cacatcctta aaatatcagc     4620

acaagttggg ggaggcaggc aatggaatat aatggaatat tcttgagact gatcacaaaa     4680

aaaaaaacct ttttaatatt tctttatagc tgagttttcc cttctgtatc aaaacaaaat     4740

aatacaaaaa atgcttttag agtttaagca atggttgaaa tttgtaggta ctatctgtct     4800

tattttgtgt gtgtttagag gtgttctaaa gacccgtggt aacagggcaa gttttctacg     4860

tttttaagag cccttagaac gtgggtattt tttttcttga gaaaagctaa tgcacctaca     4920

gatggccccc aacattctct tccttttgct tctagtcaac cttaatgggc tgttacagaa     4980

actagttcgt gtttatatac tatttccttt gatgtcctat aagtcggaaa agaaaggggc     5040

aaagagaacc tattatttgc cagtttttaa gcagagctca atctatgcca gctctctggc     5100

atctggggtt cctgactgat accagcagtt gaaggaagag agtgcatggc acctggtgtg     5160

taacgacaca atcagcacaa ctggagagag gcattaaaga accagggaag gtagtttgat     5220

ttttcattga attctacaag ctaatattgt tccacgtatg tagtcttaga ccaatagctg     5280

taactatcag ctgcaatacc atggtgacca gctgttacaa aagatttttt cctgttttat     5340

ctgaaacata ctggatttat atatgtataa gcgcctcaat ggggaattag agccagatgt     5400

tatgatttgt ttgctctttt tcttttatag tttagttata gcaaaaatat ggataatttc     5460

tagtgaatgc ataaattagg ttgcgtttct tattttgctt taaatctctg gtagtttttc     5520

cacccctgtg acacaatcct aatagacagt gtcctgtaaa tggacacaac acaataaagt     5580

caagttatta ttgctgttac tctggatgat atggaaaaca ctgccatatt ttaaatcaac     5640

tactccacgt gtttttccat ccaatcacac tgctgtgatt cagggatctt tcttctaaga     5700

cggacacatt tgaacctcag gttcatcaca aacctggtac ctgttgcttc ccagaggatg     5760

gagaagtgta gttaatcaca cctcttagtt taatctgaaa tcttgaccca gttatttaac     5820

aaataaatac ctcattgatt atatttaaaa gtaatacact tcctgtaaac aaatggggac     5880

aatgcatcca aaaaatcttt ttaaacagat tacacaaaaa ttatttccag aaaggctacc     5940

atttatcatc attatatttc aagcctctta tacttaataa gcactttcta aaaagtcttg     6000

agatcccacc attctgagga attcaatatg atcacttttt ccttctttgc ctgggagagg     6060

ttaagaggag gtttcgaagg tatagatgct attgttctga tggcccggct gaataaaatg     6120

gaaattctag tttgttagaa ttatgcattc tttttcaaga ttctcagtgt gcctaactta     6180

ttggagcaca tcagtttctt gggtaatgga aaacattacc tagagttgcc agtggcacat     6240

tacaccagta cagagcacat tccaaaggag acattggacc agttaattcc catacaagtc     6300

aaggtaacag aacaaaaggg aatcctgatg cccttttacc attgctggtt gagctcaggc     6360

actgtcatgg acacccttaa ttttaaaagg ttttaatcat tcttctataa aatacattta     6420

aaatggaaaa atacttaata tcactaaata tcagaacaat gtaacattta caaatgacat     6480

attgaaagca aaggctgttt tatttagcca agatgattac cattaggagt tactttatgt     6540

attgttgaaa gcaaatttta aacatgatgt tttagaagtg tttctgattt ttaaacctgg     6600

tttacaggta ttacttctgc acttaccaaa taatgccaga tggaaattta ttatttcttg     6660

caattcccat gatagctctg ttctttatgc attgtctcaa cactttccct tttttcccaa     6720

aatgagtaga gaattaaagc cacccaaaac agcttctgct actaaaatgt tctcatcctt     6780

tctcctccct ctccttttcc tgccacaaaa ggtgaaaaat gagatccaat cctctcacca     6840

aaatttcaaa cctaggacac tggaatgact gcagggatca gtggttctcc catatcacca     6900

tcaattaaga catataggac actgtcttcc ttcaagaggg ttacaatgtg gccatcagac     6960

aggaaaccaa acggtggata aagtattaag taactaagtg ccaaataaat gctggaaatc     7020

ttgacctctc cttgggatta tgggtgtaac aaaaatccct acatctgttt atgaaggcca     7080

tattcagtac attttaaatg gtaaataatc tgtttatgtg aagaaaaaga attaagtctt     7140

tcttccaact ctctccttgg atagcctagc acagtgcagc ctccataacc atgacattcc     7200

cgcccaagct ctcagtgcct aatcctgctt tgtcattcac atctcacaaa atcttgacat     7260

cttacattcc aatacattat caagcaagca caagtatgct ggtagtagcc tctttaaata     7320

atatgtatag acaacaacaa cgacaaaaaa tagactgttt taaagtttca gggaaagttg     7380

gtggctgatt taaagttgtg caggaaacat cttctgtgta tgaagcaaat gtcgatgttt     7440

tgaaaaaagc taggagatga ctttgaatga atgcaaggtt agtgagatcc taagctctca     7500

aaatagcata ttccctagag ctcaagaaag ctggtccagg aggttgaaaa agctattttg     7560

ttgttaaatt attttctggc ccttcttaat atttaaaaat gtatttcccc ttgtggcttt     7620

caaccacctg ctcaaaaaaa gagacttgtt acatgaaagt tttcattaaa gagctgaaaa     7680

caagaattta gagagccatt cctagaaaat gtcctactgc cctgcatttg acaaacaagc     7740

atcctttact aacaagagca ggaattcaga ggcacaagaa aaagcattgg catgagccaa     7800

agagtctgtc ttaatgttac ttttgaaaat ctgctgagcg gccaccatat gcaggctgag     7860

agctgggcac aggcgaagcc attggaagca cttcaggaac aagcacacag ctgtgggact     7920

tgaacatgca agtgttcagg ttgtgtcaag aagcttttct ttccttctat gatggaatct     7980

gttcttttct atcctacttt tttctctctt cctctcctca ccacattata ccctgctctt     8040

acgcagtaaa cgttttaatg gcccgtttat gtctcatgcc tccaaacaac actgaatttg     8100

aaacccccca ttttttcttt tcaccaccct gttgagcaat tttcccaaaa aaagggcagc     8160

aattattaaa ttgaattcaa gtaagccagc caaagatagg tcctaaattg ctagtcccag     8220

tagaaccacc tgatcctaaa ccagtgcgaa acaaacagta acaatgtccc cagctgactt     8280

cagctaagaa ccaatggctc ctacccccgc cccgcttttt tttgttgttt tttgttttgt     8340

tttgagacgg agtcttgctc tgtcccccag gctggagtgc actggcgcaa tctcgggctc     8400

actgcaacct cctcctcctc ccacattgag gcgattctcc tgcctcagcc tcccaagtag     8460

ctgggattac aggcacccgc catcacaccc agctaatttt tttttttttt tgtattatta     8520

gtagaagcca ggtttcacca tgttggccag ggtggtctcg aactcctgac ctcaagtgat     8580

ccgtccacct cggccttgca aattgctggg attacaggtg tgagccaccg tgccgagcca     8640

gccccatttt ttaaatgatg ttttggttaa gagtggacca tgagaattag ctgacagcat     8700

cccctttctc tctccctgcc ttggtgggac cctccctgtg tgaccttggt caagtcctcg     8760

aacttttgtc ccgtatttaa gatggagctg ttttacctac ttcataagac agttgcgagg     8820

tgccattgat tcttgactgc aaaatacctt gaaaccctta tataaagact gaagtcaacg     8880

gagcctagtg aaagacttac tttgtggctt gtggttgaaa gtcacatcaa aagacaaatg     8940

tggccacgtt caggaattgg agacttactg gcatggctct acagctgctc agttattaat     9000

catgcagact aacctgtcaa cactgggaga tgcaacatag caaaaggaca gagaaattag     9060

aattttttgt gcagaaagcc ctaaattccc acctgaatgt aacttacagc tcccttacct     9120

actctcacac atgccctcaa acatgctaga ttggcttata cataggccaa cacaaaatac     9180

aaacgtgacg tgttcatgta gcctagtggc tatatgccta ttctccatgt accctgcatg     9240

gtagtgctgc aaactttaaa gtacatttct ttcacagcag tatttttttt cataagtggc     9300

atataaatgt cattcaatga aatggggaaa tcacgttgag aagttggtct gtcatctccc     9360

attgagcaaa gactggcagg agataataaa aataaatatg ggcacacatg tattaatata     9420

cagcacgcat ttacaagttt attttccaga taaaattgtg ctataagaac agctctacca     9480

agacagtctg caccatttcc aagtctcagt taatttacag caactgctgc tttcggagat     9540

ggctgtgaaa atatggaagt tcctctcaag taggccaaga aacagttcta gattttacta     9600

agttttattt tgtcaggttt tttaaatttt ttcagtgagc gtggtgactg cagaggttag     9660

tgctgtgaaa agctgggcta aatattcttt ctgtaaagtc aaacaggatt ccatcccctg     9720

tgaaataaca caaaatttca ctctctaaaa gcaacagcat gtaaactaga atgaaagaag     9780

gaaattatgt acgtatgcct aatattcttt gtgaatgtct ttcatttaac taaaattata     9840

ttagaaacca gattgataaa taaaaaattc aaagtagttt taattatcct aaaa           9894


<210>  1099
<211>  2010
<212>  DNA
<213>  homo sapiens

<400>  1099
gccggggtct aggcaccacg gtggctggcg gcctgcgggc ggcgctgtgg cccgtcgggc       60

ggctccacag agccgcccta gccttccgcc ttccccaagc caacgtctcc gccgtcggct      120

ccgcggcgcc gccatggccg acgtggaaga cggagaggaa acctgcgccc tggcctctca      180

ctccgggagc tcaggctcca agtcgggagg cgacaagatg ttctccctca agaagtggaa      240

cgcggtggcc atgtggagct gggacgtgga gtgcgatacg tgcgccatct gcagggtcca      300

ggtgatggat gcctgtctta gatgtcaagc tgaaaacaaa caagaggact gtgttgtggt      360

ctggggagaa tgtaatcatt ccttccacaa ctgctgcatg tccctgtggg tgaaacagaa      420

caatcgctgc cctctctgcc agcaggactg ggtggtccaa agaatcggca aatgagagtg      480

gttagaaggc ttcttagcgc agttgttcag agccctggtg gatcttgtaa tccagtgccc      540

tacaaaggct agaacactac aggggatgaa ttcttcaaat aggagccgat ggatctgtgg      600

tcctttggga ctcatcaaag ccttggttta gcattttgtc agttttatct tcagaaattc      660

tctgcgatta agaagataat ttattaaagg tggtccttcc tacctctgtg gtgtgtgtcg      720

cgcacacagc ttagaagtgc tataaaaaag gaaagagctc caaattgaat cacctttata      780

atttacccat ttctatacaa caggcagtgg aagcagtttc agagaacttt ttgcatgctt      840

atggttgatc agttaaaaaa gaatgttaca gtaacaaata aagtgcagtt taaaacccaa      900

ctcttactct taatttgttc ctaatacgta tttttggcag ggagagggaa cggtccatga      960

aatctttatg tgatataagg attttaagtt tgggccagtg aacagggtaa ataaaattta     1020

acttttgagc atatggaatt ttgattgcct ttaaagttac tattctgtat cattgattca     1080

tcaagaaaac ctagatctgc actcacctca ctgttcaatc attgagtggt aaaggacaga     1140

agtattttct agttctggtc agatgatata attttttttt tttttttttg tgggggtgaa     1200

gtcttgctct gccacccagg ctggagtgca gtggcatgat gtcaactcac tgcaacctcc     1260

gcctcccggg ttcaagtgat tctcctgcct cagcctcccg agtagctggg attacaggtg     1320

tgtgccacca cacccggcta atttttgtat ttttagtaga gacgggattt ccccatgttg     1380

gccaggctgg tctcaaactc ctgacctcag gtgattcgcc cacctcagcc tcccaaagtg     1440

ctgggattac aggtgtgggc cactgcacct ggcccagatg atataattta actgtgtttt     1500

aggtaacatg ttaatgaggg aaaatgttta ccagtgtagc attggatcaa aaagtttatc     1560

acacagtgtt ttaataaatg gtttattctg cttaccttat ttgaattgtc attataattt     1620

tatatgcaac cttaatttgt caagtaaata ctttcattta atttgaaaga attcatattc     1680

atttgctctt tcatttgaca ataataaaat ttaaggttta ttacctggaa agagtgcaag     1740

aaaatactaa acaactttat caaactgatt cacactgagg ggaggttatt ttgtaacaaa     1800

taatggacca caagttcatt ttgtattctt ctgtagtaga ggctactgat atgaatttaa     1860

gaaaaaacct tagaatctta acttttcaca tctgcagatg cagtgtgcca ttctgaattt     1920

ttcaatctaa gggatgtgga tacatagaat gtttaaaaag ataacaatta gaatgaaaaa     1980

ttaaaattat gtatgctttt aaaaaaaaaa                                      2010


<210>  1100
<211>  3277
<212>  DNA
<213>  homo sapiens

<400>  1100
tttaaagaga gaggatcgta ttatagatac cgcgggggca aagctaaaaa aggggggagg       60

ggggaggaaa aaattcaaga agcagaaacc cctcgcggag ttttactgga agaaaaaaac      120

gggtctgaaa gattcctcct cttcatcatc atcaaccatc attcattcac taccttgaca      180

ttccgggctt tgattgacag ctggagtggc aaaaagccat gaaacacgac agttcggtta      240

catgtgggct gctgacgggc cgctcgtaac cttcagttcg ggggcttgac aatttttttc      300

ttctttttct tctttttctt ttctttcttt ttttttccaa ctgaggggaa gagaagagaa      360

agagggggaa aggaggaccg aagaggagga ggaggggagg ggggaggagg aggaggtgga      420

ggaggaggag gaagatcagg aggaggagga agaagaggaa aaaagagaaa aagaagaaat      480

atcacagaaa aaaaaattct tcgttgtcta gactgggctt tttttccccc ctaaaaaata      540

gcatattgga gaattgggag aagtctcttt ggtttggaaa aaaaaaaaag gaatcttcag      600

cctagatcac tttcttatcc ggactgggat attaaatata cgacacatcc aggagtttat      660

tggagcgcag actgatggcg caaaggtacg atgagctgcc ccattacggc gggatggacg      720

gagtaggggt tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg      780

ttcaccacct gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc      840

cgcaccccaa tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg      900

acaaggacgc gatctatggg cacccgttgt ttcctctgtt agctctggtc tttgagaagt      960

gcgagctggc gacctgcact ccccgggaac ctggagtggc tggcggagac gtctgctcct     1020

ccgactcctt caacgaggac atcgcggtct tcgccaagca ggttcgcgcc gaaaagccac     1080

ttttttcctc aaatccagag ctggacaatt tgatgataca agcaatacaa gtactaaggt     1140

ttcatctttt ggagttagaa aaggtccacg aactgtgcga taacttctgc caccgataca     1200

ttagctgttt gaaggggaaa atgcccatcg acctcgtcat tgatgaaaga gacggcagct     1260

ccaagtcaga tcatgaagaa ctttcaggct cctccacaaa tctcgctgac cataaccctt     1320

cttcttggcg agaccacgat gatgcaacct caacccactc agcaggcacc ccagggccct     1380

ccagtggggg ccatgcttcc cagagcggag acaacagcag tgagcaaggg gatggtttag     1440

acaacagtgt agcttcacct ggtacaggtg acgatgatga tccggataag gacaaaaaac     1500

gccagaagaa aagaggcatt ttccccaaag tagcaacaaa tatcatgaga gcatggctct     1560

tccagcatct cacacatccg tacccttccg aagagcagaa gaaacagtta gcgcaagaca     1620

caggacttac aattctccaa gtaaacaact ggtttattaa tgccagaaga agaatagtac     1680

agcccatgat tgaccagtca aatcgagcag gttttcttct tgatccttca gtgagccaag     1740

gagcagcata tagtccagag ggtcagccca tggggagctt tgtgttggat ggtcagcaac     1800

acatggggat ccggcctgca ggtttgcaga gcatgccagg ggactacgtt tctcagggtg     1860

gtcctatggg aatgagtatg gcacagccaa gttacactcc tccccagatg accccacacc     1920

ctactcaatt aagacatgga cccccaatgc attcatattt gccaagccat ccccaccacc     1980

cagccatgat gatgcacgga ggacccccta cccaccctgg aatgactatg tcagcacaga     2040

gccccacaat gttaaattct gtagatccca atgttggcgg acaggttatg gacattcatg     2100

cccaatagta taagggaact caagggaaaa ggaaacacac gcaaaaacta ttttaagact     2160

ttctgaactt tgaccagatg ttgacactta atatgaaatt ccagacagct gtgattattt     2220

tttacttttg tcatttttca tcaagcaaca gaggaccaat gcaacaagaa cacaaatgtg     2280

aaatcatggg ctgactgaga caattctgtc catgtaaaga tcctctggaa aaagactccg     2340

agagttataa ctactgtagt ataaatatag gaactaagtt aaacttgtac atttctgttg     2400

atcacgccgt tatgttgcct caaatagttt tagaagagaa aaaaaaatat atccttgttt     2460

tccacactat gtgtgttgtt cccaaaagaa tgactgtttt ggttcatcag tgaattcacc     2520

atccaggaga gactgtggta tatattttaa acctgttggg ccaatgagaa aagaaccaca     2580

ctggagatca tgatgaactt ttggctgaac ctcatcactc gaactccagc ttcaagaatg     2640

tgttttcatg cccggccttt gttcctccat aaatgtgtcc tttagtttca aacagatctt     2700

tatagttcgt gcttcataag ccaattctta ttattatttt tgggggactc ttcttcaaag     2760

agcttgccaa tgaagattta aagacagagc aggagcttct tccaggagtt ctgagccttg     2820

gttgtggaca aaacaatctt aagttgggca gctttcctca acacaaaaaa aagttattaa     2880

tggtcattga accataacta ggactttatc agaaactcaa agcttggggg ataaaaagga     2940

gcaagagaat actgtaacaa acttcgtaca gagttcggtc tattaattgt ttcatgttag     3000

atattctatg tgtttacctc aattgaaaaa aaaaagaatg tttttgctag tatcagatct     3060

gctgtggaat tggtattgta tgtccatgaa ttcttctttt ctcagcacgt gttcctcact     3120

agaagaaaat gctgttacct ttaagctttg tcaaatttac attaaaatac ttgtatgagg     3180

actgtgacgt tatgttaaaa aaaaaaaggt gttaagtcac aaaaagcggt aataaatatt     3240

tcatttttga ttttttgtta aaaaaaaaaa aaaaaaa                              3277


<210>  1101
<211>  3646
<212>  DNA
<213>  homo sapiens

<400>  1101
ggcgccacca cgtgtgtccc tgcgcccggt ggccaccgac tcagtccctc gccgaccagt       60

ctgggcagcg gaggagggtg gttggcagtg gctggaagct tcgctatggg aagtcgttcc      120

tttgctctct cgcgcccagt cctcctccct ggttctcctc agccgctgtc ggaggagagc      180

acccggagac gcgggctgca gtcgcggcgg cttctccccg cctgggcggc cgcgccgctg      240

ggcaggtgct gagcgcccct agagcctccc ttgccgcctc cctcctctgc ccggccgcag      300

cagtgcacat ggggtgttgg aggtagatgg gctcccggcc cgggaggcgg cggtggatgc      360

ggcgctgggc agaagcagcc gccgattcca gctgccccgc gcgccccggg cgcccctgcg      420

agtccccggt tcagccatgg ggacctctcc gagcagcagc accgccctcg cctcctgcag      480

ccgcatcgcc cgccgagcca cagccacgat gatcgcgggc tcccttctcc tgcttggatt      540

ccttagcacc accacagctc agccagaaca gaaggcctcg aatctcattg gcacataccg      600

ccatgttgac cgtgccaccg gccaggtgct aacctgtgac aagtgtccag caggaaccta      660

tgtctctgag cattgtacca acacaagcct gcgcgtctgc agcagttgcc ctgtggggac      720

ctttaccagg catgagaatg gcatagagaa atgccatgac tgtagtcagc catgcccatg      780

gccaatgatt gagaaattac cttgtgctgc cttgactgac cgagaatgca cttgcccacc      840

tggcatgttc cagtctaacg ctacctgtgc cccccatacg gtgtgtcctg tgggttgggg      900

tgtgcggaag aaagggacag agactgagga tgtgcggtgt aagcagtgtg ctcggggtac      960

cttctcagat gtgccttcta gtgtgatgaa atgcaaagca tacacagact gtctgagtca     1020

gaacctggtg gtgatcaagc cggggaccaa ggagacagac aacgtctgtg gcacactccc     1080

gtccttctcc agctccacct caccttcccc tggcacagcc atctttccac gccctgagca     1140

catggaaacc catgaagtcc cttcctccac ttatgttccc aaaggcatga actcaacaga     1200

atccaactct tctgcctctg ttagaccaaa ggtactgagt agcatccagg aagggacagt     1260

ccctgacaac acaagctcag caagggggaa ggaagacgtg aacaagaccc tcccaaacct     1320

tcaggtagtc aaccaccagc aaggccccca ccacagacac atcctgaagc tgctgccgtc     1380

catggaggcc actgggggcg agaagtccag cacgcccatc aagggcccca agaggggaca     1440

tcctagacag aacctacaca agcattttga catcaatgag catttgccct ggatgattgt     1500

gcttttcctg ctgctggtgc ttgtggtgat tgtggtgtgc agtatccgga aaagctcgag     1560

gactctgaaa aaggggcccc ggcaggatcc cagtgccatt gtggaaaagg cagggctgaa     1620

gaaatccatg actccaaccc agaaccggga gaaatggatc tactactgca atggccatgg     1680

tatcgatatc ctgaagcttg tagcagccca agtgggaagc cagtggaaag atatctatca     1740

gtttctttgc aatgccagtg agagggaggt tgctgctttc tccaatgggt acacagccga     1800

ccacgagcgg gcctacgcag ctctgcagca ctggaccatc cggggccccg aggccagcct     1860

cgcccagcta attagcgccc tgcgccagca ccggagaaac gatgttgtgg agaagattcg     1920

tgggctgatg gaagacacca cccagctgga aactgacaaa ctagctctcc cgatgagccc     1980

cagcccgctt agcccgagcc ccatccccag ccccaacgcg aaacttgaga attccgctct     2040

cctgacggtg gagccttccc cacaggacaa gaacaagggc ttcttcgtgg atgagtcgga     2100

gccccttctc cgctgtgact ctacatccag cggctcctcc gcgctgagca ggaacggttc     2160

ctttattacc aaagaaaaga aggacacagt gttgcggcag gtacgcctgg acccctgtga     2220

cttgcagcct atctttgatg acatgctcca ctttctaaat cctgaggagc tgcgggtgat     2280

tgaagagatt ccccaggctg aggacaaact agaccggcta ttcgaaatta ttggagtcaa     2340

gagccaggaa gccagccaga ccctcctgga ctctgtttat agccatcttc ctgacctgct     2400

gtagaacata gggatactgc attctggaaa ttactcaatt tagtggcagg gtggtttttt     2460

aattttcttc tgtttctgat ttttgttgtt tggggtgtgt gtgtgtgttt gtgtgtgtgt     2520

gtgtgtgtgt gtgtgtgtgt gtgtttaaca gagaatatgg ccagtgcttg agttctttct     2580

ccttctctct ctctcttttt tttttaaata actcttctgg gaagttggtt tataagcctt     2640

tgccaggtgt aactgttgtg aaatacccac cactaaagtt ttttaagttc catattttct     2700

ccattttgcc ttcttatgta ttttcaagat tattctgtgc actttaaatt tacttaactt     2760

accataaatg cagtgtgact tttcccacac actggattgt gaggctctta acttcttaaa     2820

agtataatgg catcttgtga atcctataag cagtctttat gtctcttaac attcacacct     2880

actttttaaa aacaaatatt attactattt ttattattgt ttgtccttta taaattttct     2940

taaagattaa gaaaatttaa gaccccattg agttactgta atgcaattca actttgagtt     3000

atcttttaaa tatgtcttgt atagttcata ttcatggctg aaacttgacc acactattgc     3060

tgattgtatg gttttcacct ggacaccgtg tagaatgctt gattacttgt actcttctta     3120

tgctaatatg ctctgggctg gagaaatgaa atcctcaagc catcaggatt tgctatttaa     3180

gtggcttgac aactgggcca ccaaagaact tgaacttcac cttttaggat ttgagctgtt     3240

ctggaacaca ttgctgcact ttggaaagtc aaaatcaagt gccagtggcg ccctttccat     3300

agagaatttg cccagctttg ctttaaaaga tgtcttgttt tttatataca cataatcaat     3360

aggtccaatc tgctctcaag gccttggtcc tggtgggatt ccttcaccaa ttactttaat     3420

taaaaatggc tgcaactgta agaacccttg tctgatatat ttgcaactat gctcccattt     3480

acaaatgtac cttctaatgc tcagttgcca ggttccaatg caaaggtggc gtggactccc     3540

tttgtgtggg tggggtttgt gggtagtggt gaaggaccga tatcagaaaa atgccttcaa     3600

gtgtactaat ttattaataa acattaggtg tttgttactt aaaaaa                    3646


<210>  1102
<211>  3557
<212>  DNA
<213>  homo sapiens

<400>  1102
agattgcgcg agggggagcg agcgagcggg cgctgccagg agcccgcagc cctggcgccc       60

gccgccgccc ggagccccgc aatatgccgc cgcggccctc tggctctagg ccatggcgag      120

gctctgccgg cgtgtcccct gcaccctgct tctcggcctg gccgtggtgc tgctgaaagc      180

gcggctggtc cccgcggccg ccagagcgga actcagccgc tccgacctca gcctcatcca      240

acagcagcag cagcagcagc aacaacaaca acaacagcaa aagcagctgg aggaggctga      300

ggaggagagg acagaggtgc ctggggcaac ctccaccttg acggttccag tgtctgtatt      360

tatgttgaaa gtccaggtga atgacatcat cagtcgtcag tacctgagcc aagcagttgt      420

agaagtgttt gtaaactaca cgaagacaaa ttccacagta actaaaagca atggagcagt      480

gctgataaaa gtaccctaca aattaggact tagtttaact attattgctt acaaagatgg      540

ctacgtgttg acccctctgc cttggaaaac cagaagaatg ccaatatatt catcagttac      600

actttcactg ttcccgcaaa gccaagcaaa tatatggcta tttgaagaca ctgttttaat      660

tactggaaaa ttagctgatg ccaagtctca accaagtgtt cagttttcaa aagccttaat      720

taaacttcct gacaaccatc atattagcaa cgttactggc tatcttacag ttctacaaca      780

gtttttgaaa gtggacaatt ttctgcatac aactggaatt actctcaata aaccaggttt      840

tgaaaacatt gaattgactc ctcttgctgc aatatgtgtg aaaatatatt ctggaggaaa      900

agaactaaag gtcaatggct ctattcaagt ttctcttcct cttctacgtc tgaatgatat      960

aagtgcaggg gatcgcatac ctgcttggac atttgatatg aacacaggtg cttgggtaaa     1020

tcatggtcgg ggaatggtca aggaacataa caatcattta atctggacat atgatgcacc     1080

acatttgggg tactggatag cagctccact tccaggaact agaggttcag gtataaatga     1140

agattccaag gacataactg cctaccacac agtgtttctt acagccatat taggaggaac     1200

aatagtcatt gtcattggat tttttgctgt actactttgt tattgcaggg acaagtgtgg     1260

tactccacag aaaagagaaa gaaatatcac taaacttgag gtcctcaaga gagaccagac     1320

aacttcaaca acacacataa atcatatcag tacagttaaa gttgcattaa aagctgagga     1380

caagtcgcag ttattcaatg ccaaaaactc ctcatatagt cctcagaaaa aggaaccatc     1440

aaaggcagaa acagaagaaa gagtttccat ggtaaaaact cgggacgatt ttaaaatcta     1500

caatgaagat gtttcatttc tatcagtcaa tcaaaataat tactcaagaa acccaacaca     1560

gtctttggag cccaatgtag ggtccaaaca acctaaacat attaacaaca atctatcttc     1620

atctctaggt gatgctcaag atgaaaagag gtatctcaca ggtaatgagg aggcgtatgg     1680

gcgttcccat attcctgaac agcttatgca tatttacagc caacccattg ccatccttca     1740

aacatctgac cttttctcca caccggaaca attacatact gctaagtcag ctactttgcc     1800

aagaaaggga cagttagtct atggccaatt gatggaacca gtaaatcgag agaactttac     1860

gcagaccttg cccaaaatgc caattcattc tcatgcacag cccccagatg ccagggaaga     1920

ggatatcata cttgaaggtc aacagagcct gccatcccag gcttcagatt ggagccgata     1980

ctcaagcagc ttactggaat ccgtctctgt tcctggaaca ctaaatgagg ctgttgtaat     2040

gactccattt tcatcggaac ttcaaggaat ttcagaacag accctcctgg agctgtccaa     2100

aggaaagccc tccccgcatc ccagagcctg gtttgtgtct cttgatggaa agccagttgc     2160

acaagtgagg cactccttta tagacctgaa aaagggcaag agaacccaga gcaatgacac     2220

cagtctggac tctggggtgg acatgaatga gcttcactca agtagaaagc tcgagaggga     2280

gaaaacattc atcaaaagca tgcatcagcc caagatcctt tacttagaag atttagacct     2340

aagcagcagt gagagtggaa ccaccgtctg ttcccctgag gacccagctt taaggcacat     2400

cctagatgga gggagtggag tgatcatgga gcaccctgga gaagagtcgc caggaaggaa     2460

aagcactgtt gaagattttg aagctaatac atcccccact aaaagaaggg gcagaccacc     2520

actagccaaa agagatagca agactaacat ctggaagaag cgagaggaac gcccactgat     2580

tcccataaat taactccaat ggggattgtg tgtctgctgt ctcgtgctgt ttattcttgc     2640

ttcttgttgt aaattgcagt acgaacttaa gaaaatgaga ctgagcaatc tcatggttct     2700

tggacatgtc tcaagcagag taaatggtaa ttcagtaatc agagagaaag ataccaagga     2760

atgctttttc tggcctattc atttattttt gggtgatgaa tttacagtat ctaagttttc     2820

aaaatgtaaa atagcttcaa gatgttagtt atctgaaaat gttgctcagc cagccagttt     2880

ggccttgact ctcttaagaa taacagtgaa atatatactc ctcaagttgc ctccaaaaat     2940

gttgcctcta ccatggtgac taccccatgg aacatttaga aacaaaactg acttcaggca     3000

tcatattatt ttaaatgtta ctattacgtc ttcttctgcc tatacttaaa aataacttga     3060

taaatgactt ggactgatgt tactctggag ttatcacaaa gaaaatgttg tttggtcttt     3120

aaagagcatg tgtattgtat catcccaaac gtaaatccta catttatata agatgggcaa     3180

gaagctactt ggtcattaga gagggagaca ccagctcttt ggttgttttt ggatataact     3240

ttacaaaata agtaagatgt taatttagaa atttgagaaa ttaatgctct aatactgagt     3300

ttttatttaa aaattatttt ttcttcccct caacaatgaa gcaagcttag ctgtcaaggg     3360

aaacttttta caaatctgaa aaaaacaatc tatgactttg gtttaaggct cactgatact     3420

tttaggctaa attggtttta atatatttct tctattctaa aaacctgaac tcagtcactt     3480

aaaggctatg aaatttaaaa aaaaagtcga tgtgaaagtt tcttttgaac actaaaataa     3540

aatatgtgca gataaaa                                                    3557


<210>  1103
<211>  5808
<212>  DNA
<213>  homo sapiens

<400>  1103
acaaacatgt cttgcctgca ccctaggcaa acgtggaaag gcgcagctct ggtacaccgg       60

aaagcatggt ggatggggag gtccctggat ggccggttgc aggtgtccca tcggaagggg      120

ctccctcatg tcatctactg ccgcctgtgg cgatggccag acctgcacag ccaccacgag      180

ctacgggcca tggagctgtg tgagttcgcc ttcaatatga agaaggacga ggtctgcgtg      240

aatccctacc actaccagag agtagagaca ccagttctac ctcctgtgtt ggtgccacgc      300

cacacagaga tcccggccga gttcccccca ctggacgact acagccattc catccccgaa      360

aacactaact tccccgcagg catcgagccc cagagcaata ttccagagac cccaccccct      420

ggctacctga gtgaagatgg agaaaccagt gaccaccaga tgaaccacag catggacgca      480

ggttctccaa acctatcccc gaatccgatg tccccagcac ataataactt ggacctgcag      540

ccagttacct actgcgagcc ggccttctgg tgctccatct cctactacga gctgaaccag      600

cgcgtcgggg agacattcca cgcctcgcag ccatccatga ctgtggatgg cttcaccgac      660

ccctccaatt cggagcgctt ctgcctaggg ctgctctcca atgtcaacag gaatgcagca      720

gtggagctga cacggagaca catcggaaga ggcgtgcggc tctactacat cggaggggag      780

gtcttcgcag agtgcctcag tgacagcgct atttttgtcc agtctcccaa ctgtaaccag      840

cgctatggct ggcacccggc caccgtctgc aagatcccac caggatgcaa cctgaagatc      900

ttcaacaacc aggagttcgc tgccctcctg gcccagtcgg tcaaccaggg ctttgaggct      960

gtctaccagt tgacccgaat gtgcaccatc cgcatgagct tcgtcaaagg ctggggagcg     1020

gagtacagga gacagactgt gaccagtacc ccctgctgga ttgagctgca cctgaatggg     1080

cctttgcagt ggcttgacaa ggtcctcacc cagatgggct ccccaagcat ccgctgttcc     1140

agtgtgtctt agagacatca agtatggtag gggagggcag gcttggggaa aatggccatg     1200

caggaggtgg agaaaattgg aactctactc aacccattgt tgtcaaggaa gaagaaatct     1260

ttctccctca actgaagggg tgcacccacc tgttttctga aacacacgag caaacccaga     1320

ggtggatgtt atgaacagct gtgtctgcca aacacattta ccctttggcc ccactttgaa     1380

gggcaagaaa tggcgtctgc tctggtggct taagtgagca gaacaggtag tattacacca     1440

ccggccccct ccccccagac tctttttttg agtgacagct ttctgggatg tcacagtcca     1500

accagaaaca cccctctgtc taggactgca gtgtggagtt caccttggaa gggcgttcta     1560

ggtaggaaga gcccgcaggg ccatgcagac ctcatgccca gctctctgac gcttgtgaca     1620

gtgcctcttc cagtgaacat tcccagccca gccccgcccc gccccgcccc accactccag     1680

cagaccttgc cccttgtgag ctggatagac ttgggatggg gagggaggga gttttgtctg     1740

tctccctccc ctctcagaac atactgattg ggaggtgcgt gttcagcaga acctgcacac     1800

aggacagcgg gaaaaatcga tgagcgccac ctctttaaaa actcacttac gtttgtcctt     1860

tttcactttg aaaagttgga aggatctgct gaggcccagt gcatatgcaa tgtatagtgt     1920

ctattatcac attaatctca aagagattcg aatgacggta agtgttctca tgaagcagga     1980

ggcccttgtc gtgggatggc atttggtctc aggcagcacc acactgggtg cgtctccagt     2040

catctgtaag agcttgctcc agattctgat gcatacggct atattggttt atgtagtcag     2100

ttgcattcat taaatcaact ttatcatatg ctcttttaaa tgtttggttt atatattttc     2160

tttaaaaatc ctgggctggc acattgactg ggaaacctga gtgagaccca gcaactgctt     2220

ctctcccttc tctctcctga ggtgaagctt ttccaggttt tgttgaagag atacctgcca     2280

gcacttctgc aagctgaaat ttacagaagc aaattcacca gaagggaaac atctcaggcc     2340

aacataggca aatgaaaagg gctattaaaa tatttttaca cctttgaaaa ttgcaggctt     2400

ggtacaaaga ggtctgtcat cttccccctg ggatataaga tgatctagct cccggtagag     2460

gatcaccggt gacaactata gcagttgtat tgtgtaacaa gtactgctcc cagcagcaat     2520

tagggagaaa actagtctaa attatttcaa ctggaaaaaa gaaaaaagag tcctcttctt     2580

ttcccagcct tttgcagaac acagtagaca gaactgccac cttcaattgg tactttattc     2640

tttgctgctg tttttgtata aaatgaccta tcccacgttt ttgcatgaat ttatagcagg     2700

aaaaatcaag ggatttccta tggaagtcct gctttattcc aggtgaaggg aaggaagtgt     2760

atatactttt ggcaagtcat acagctcaaa tgtgatgaga tttctgatgt tagagggaga     2820

tggagaggct tcctgatgcc tcatctgcag ggtcctgtgc ctctgaagtt ctagccatga     2880

ggtttccagg taggacagct gctccccaag cctcctgagg acacaggaag agacggaagg     2940

agcaccttga cagacttgtg tgagtcttct cgaaggaggg ttgactcaga acccagagac     3000

aatacaaaac ccctcacttc ctctgagagg gccaaatgct gtgagtctga agtatgtgcc     3060

tggtgtgaaa tgatctatgg cctgtttctt acacaggaag ccccctgaac ctcctgtaca     3120

tgtgttcatg ttcccagcca gctctgagac ccaggaacca aatattccat tttggcttct     3180

gctagagcag tcatggttcc tctcctaaaa gccatgggca gcagtttccg agggcctgca     3240

tgatccacct gctgcacgat cctatgaggg cttcctgtgg cacacagccc tctgggtgct     3300

tgggaactag cttcaggcac agcctgattc tggtgatcca gtgatctatg gaagtcgtgt     3360

cttactccag gtgaaggggg aaaaaaaaag cctatacttt ggcaggttat gaactttgaa     3420

tgtgatgaaa tgacacgttt ggctgcattt ggatggtgtc ttagaaccct cattgctcag     3480

acctgaaggc tacttctagg agcatgaagt ttgagttttg tgtttttcca aaggatactt     3540

ccttggccct ttttctttat tgactagacc accagaggag gatgtgtggg attgtaggca     3600

aacccacctg tggcatcact gaaaataaat ttgatcatac ctaagaggtt aggaaatggt     3660

gccattccca ccttagagtg ctacataggt gctttgggcg tatgtaacat tagtgtcctt     3720

ccttgaagcc acaagctagt tttcttagtt ttaaaatcct gttgtatgaa tggcatttgt     3780

atattaaaac acttttttaa aggacagttg aaaagggcaa gaggaaacca gggcagttct     3840

agaggagtgc tggtgactgg atagcagttt taagtggcgt tcacctagtc aacacgaccg     3900

cgtgtgttgc ccctgccctg ggctccccgc catgacatct tcaccttgca gcttgtgctg     3960

agactgaccc aagtgcagct agcactggga cacagatcct tgtcttcagc accttccaag     4020

gagccaactt ttattccctt tcctctctcc cctccccacc tcgcttcttc ccaatttagt     4080

aacttagatg cttccagcac atacgtaggt agctacccca gccggtttgg attacaggcc     4140

tgtgctggaa catcatctca gttggccacc ttcctggcag gctgtagacc tgacattttg     4200

agacaagcct agagtcagga gcagggactt tgactcttag gaagagcaca catgagggca     4260

aggctgctgg cagacgtctc cattgtcctt atgttgtctg tgttgtattt tttttttttt     4320

attgaccatg gtgattattt ttttaaacca tcgttaatat actgaagtga gctatagcac     4380

atatcatgtg cttagtttgt ttatttttct ccatctcccc ttggcttcct agagtttgga     4440

catattccag gctaaatgct tttactcaag actacagaaa ggtttgaagt agtgtgtgca     4500

tggcatgcac gtatgtaagt aatctgggga agaagcaaag atctgtttca ttcttagcct     4560

caggcctcat gagggtctcc acagggccgg agctcaggtt acaccactcc ttcgtcctta     4620

caggagatgt agggagaaga atctgcaggc tgcttgtagg actgttcacc aagggggata     4680

ccagcagcaa gagagtgcac ccgtttagcc ctggaccctg tttcttactg tgtgacttgg     4740

ctagagttgg gagttccccc aaaataaacg tgtccccatt ttaccagaac caaacctcaa     4800

cacagcgaag ctgtactgtc tttgtgtggc aaagatgttc ccttgtaggc ccctttcagg     4860

taaccgtctt cacaatgtat tttcatcaca gtttaaggag catcagccgc ttctcaagtg     4920

ggtagggaaa gcagaaaaac gtacgcaaga ggacatggat ccaaaatgat gatgaagcat     4980

ctcccatggg gaggtgatgg tggggagatg atgggctaaa caggcaactt ttcaaaaaca     5040

cagctatcat agaaaagaaa cttgcctcat gtaaactgga ttgagaaatt ctcagtgatt     5100

ctgcaatgga ttttttttta atgcagaagt aatgtatact ctagtattct ggtgttttta     5160

tatttatgta ataatttctt aaaaccattc agacagataa ctatttaatt ttttttaaga     5220

aagttggaaa ggtctctcct cccaaggaca gtggctggaa gagttggggc acagccagtt     5280

ctgaatgttg gtggagggtg tagtggcttt ttggctcagc atccagaaac accaaaccag     5340

gctggctaaa caagtggccg cgtgtaaaaa cagacagctc tgagtcaaat ctgggccctt     5400

ccacaagggt cctctgaacc aagccccact cccttgctag gggtgaaagc attacagaga     5460

gatggagcca tctatccaag aagccttcac tcaccttcac tgctgctgtt gcaactcggc     5520

tgttctggac tctgatgtgt gtggagggat ggggaataga acattgactg tgttgattac     5580

cttcactatt cggccagcct gaccttttaa taactttgta aaaagcatgt atgtatttat     5640

agtgttttag atttttctaa cttttatatc ttaaaagcag agcacctgtt taagcattgt     5700

acccctattg ttaaagattt gtgtcctctc attccctctc ttcctcttgt aagtgccctt     5760

ctaataaact tttcatggaa aagctcctgt gccaggagct cagtctga                  5808


<210>  1104
<211>  4899
<212>  DNA
<213>  homo sapiens

<400>  1104
aatcggcggt gcccgcgcag ggtgctacgc cacgcccagc cgggccggcc gttcctaccg       60

gcctggtcca gcggacagcg gctgcagcgg gggcgccggc tgggagctgt ttttggaagg      120

aagaaagatg gaaagcggtg cagttctgct ggaatccaaa tcctccccat ttaacctact      180

gcatgagatg catgagcttc gcctcctggg tcacctgtgt gacgtgacag tcagcgtgga      240

gtatcagggt gtccgcaaag acttcatggc ccacaaggca gtgctggctg ccaccagcaa      300

gttttttaag gaagtgttcc ttaatgagaa gagtgtggat ggtactagga ctaatgtcta      360

cttaaatgaa gtgcaggttg ctgactttgc ttcatttctt gagtttgtct acactgcaaa      420

ggtacaggtg gaagaagatc gggtgcagcg aatgctggaa gtggctgaaa agctgaaatg      480

tttggattta tcagaaactt gttttcaatt aaagaaacag atgttagagt cagtactttt      540

ggagttgcaa aatttctcag agtctcagga ggtggaggtg agcagtggct cccaagttag      600

tgctgctcct gcccccaggg caagtgtggc caccgatggc cctcacccca gtggtctcac      660

ggattccttg gactacccag gagagagagc cagcaatggc atgtcttcag atttgccacc      720

gaagaagtcc aaggacaaac tagacaagaa gaaagaggta gttaaacctc cctaccctaa      780

aatcaggaga gctagtggaa ggctggctgg gaggaaggtc tttgtggaga tccctaaaaa      840

gaaatatacg agaagactcc gagagcagca gaaaactgct gagggtgatg tgggggacta      900

caggtgtccc caggaccaaa gcccggacag ggtgggcacg gagatggagc aggtttccaa      960

aaatgagggt tgccaggcag gtgctgagtt ggaggaattg tcaaagaaag cagggccgga     1020

ggaggaagag gaggaggagg aggaggacga agaaggggag aagaagaaga gcaactttaa     1080

gtgcagcatt tgcgagaagg cgtttctgta tgagaagagc ttcctgaagc acagcaagca     1140

ccgccacggc gtggccaccg aggtggtgta ccgctgcgac acctgcggcc agaccttcgc     1200

caaccgctgc aacctgaaga gccaccagcg ccacgtgcac agcagcgagc gccatttccc     1260

atgcgagctg tgcgggaaga agttcaagcg caagaaggac gtgaagcggc acgtgctgca     1320

ggtgcatgag ggcggcggcg agcggcaccg ctgcggccag tgcggcaagg gcctgagttc     1380

caagacagcg ctgcggctgc acgagcgcac acacacggga gaccggccct acggctgcac     1440

cgagtgcggc gccaggttct cgcagccgtc cgcgctcaag acgcacatga gaattcatac     1500

aggggaaaaa ccttttgtct gtgatgaatg tggtgcaaga ttcactcaga accacatgct     1560

gatttatcat aaaaggtgtc acacaggtga aagacctttt atgtgtgaaa catgtggcaa     1620

gagttttgct tctaaggagt acttaaaaca ccacaataga atccatactg gatccaaacc     1680

ctttaaatgt gaagtatgtt tcaggacttt tgcccagcgg aattcactgt accagcatat     1740

taaagtccac acaggggagc gtccctactg ctgtgaccag tgcggcaagc agttcaccca     1800

gctcaacgcc ctccagcgcc accgccgcat ccacacaggg gagaggccat tcatgtgcaa     1860

tgcgtgcgga cggacattca ccgacaagtc cactcttcgg cggcacacct caatacacga     1920

taagaatact ccatggaagt ctttccttgt cattgtagat ggctcgccca agaacgatga     1980

cggacacaag actgaacagc ctgacgaaga gtatgtgtca tccaagcttt cggataaatt     2040

gctgtctttt gcagaaaatg gccatttcca caacctggct gcagtccaag acactgtacc     2100

taccatgcag gagaacagtt ctgctgacac agcctgcaag gcagatgact ccgtggtgtc     2160

ccaggacacc ctcctggcca ccaccatcag tgagcttagc gagctgaccc cacagacaga     2220

ctcgatgccc acacagcttc actctttgag caacatggaa taagagcttc aagcagttcc     2280

catcctgtta gtctgcgtgt gtggtagctg aactcaagat gatgtggggc taagaaaaat     2340

aattgtccat gtgcaaagat gtgggcaaga atggcctctg cagattttcc tgaacttctg     2400

ctaacttgca cggctttatc acagcatttt taaagctttc cctcaaaaat cctgatctgc     2460

atgatctcag ctactttatt gacaaaaagg cagtgaacat aacctcactt aattctggtg     2520

tagggtgtat gtgctaatcg ttctaattct tgattaccta gtttatagat aactgctggt     2580

cttaattgca gagtacagag aactgaacca gctcctgata ttgtagttag cagtcttcct     2640

ggcttctcac tctgccttat atttccatgt gggtttactt ctctcataac tactttcaag     2700

gtatttttct tccaagctga aataaaactg gggccacata ttttcagtca tttcttccct     2760

gttgaattga agcaaatcag attttctgtg gggaccctca aatgcaactg aagaaataga     2820

ttgttgcatt cattcctccc caccccccat ttgtaggcag taaacaaagt atgactgaca     2880

gattgaacac ctgcaaaact gctagcgtaa tctcagcaca tacgcagcta ggaagtttgt     2940

cataaaatca acttagaaat gagatgaggc tgttcagttt gtcttaaaaa aatcagatta     3000

ggtaaaagct gtcctaccaa agagtctagc aaaacaatat agtatttttt tgcagaggca     3060

tgaaaaatta agacgcttta gagtacttga aagttgtgta gtcattttat ttgcaaaatg     3120

aggtgactgt ggcaaattat agaacacaga gtattattac ttttgccagg tttttctgac     3180

ttgatttctg taatttccag aaacccagac ttctcatttc cacacctaga gatggaaaca     3240

ggcaagtaac tgacatgtct atttccttgg gagcatgtga gaacatagca gtagggacca     3300

aaagtctcag cacacttacc tccgattatg ccttaaagag ttgattgtga agaaccagta     3360

actttgtccc aaatgcttct ttggctgttt catgcaggac ttaattattg cttttaaaaa     3420

ttcacaatga aaagacgatt ctgctgtatt tgttaaacgt tgacatttgg ttctagggcc     3480

ttgagtatgt gccacgtgct tgtgaaatgc tatgattcac atgtaacatt taaacattaa     3540

tttaaaaagg gaaccttgga gaattctttt gttcactagt tccttttttc tctacatttt     3600

taatttatta aacttgctgt gaaaacactt tgattttcta agaggaaggt actttaagtt     3660

ccagaatgaa catgtagctg cactatgcca gaaattaatg agggaagact ttcttcctaa     3720

gtgcttatgt tttaacttat gttagtgaaa ccactacaag gtgtttcagg cgctgataac     3780

atgcttcaca cctgcccttg gaggtcacag tactaattta cttcaaattt agttatgaca     3840

gtgtcactgt atcctagtta tgtttacagc acaaataaat aatgactgtc atacatccag     3900

aggagaccga acctgcccag ctgatgtact gttttatgga ataaagtcac ttgatcagaa     3960

ggaattgaaa caatagatca ttttgttacc tactggaggg atttttgtct tgaatttgtt     4020

tccttagaaa ttctacaaaa aaatgttgtt aataaatgtc tgctttgtaa aagcagtttt     4080

gcaatttttt aaagatctat ttctgttata atttaggttc tgcagaaata tgattcttaa     4140

ttgaaacata taatttgctt aattacgtga ataatgaaat gtaaaatccg ggtccataag     4200

cctttatttc atacagtcct aggattaagc tgtttaactg cttggatccc agttggtctc     4260

tggcagtggg atcctggaga ggagaaatcc tggcctctgc tcatgcgcag gccacaaccg     4320

ggctggaagt gcggttgagc tctctgccac tttcttcaat gtaaaaagta ggcatcaaag     4380

atacgacttc tactatatac atttctctgt ccctgagaac agagaaacgt aaccctgtag     4440

gggactggtt acagaggacc tcctggagca tctgccccat tcctccaagt ccaagcacag     4500

ccatgctgag tggaagcgag gccaccatct gagtggattg gtcccaagtg tgtaatgagg     4560

aaagtggcca ggtgccggca cagtgcctct cccagagcct caagaagggc catttaggag     4620

cttgcttcaa ccattttcca accattttct gtgaaatgct gtcagcccaa actccaaagg     4680

gatgtgcagc ctttcgtttt accaaattct ttgctgtcgt ttggaaaaaa tgggccatgt     4740

ggtggagacc tttatttaag gtgattttta cagaaatgtg attttgctgt aggtgattat     4800

ccaaacaagt aaatttgagt gtataattta atttttaacc tgttaaataa accttgtccc     4860

tccaaggagt tcatttttgg gaaaaaaaaa aaaaaaaaa                            4899


<210>  1105
<211>  2336
<212>  DNA
<213>  homo sapiens

<400>  1105
ggaagaaaca cagatggcgg cggcgcagcg ccattccggg ccgggagcag gcagccagca       60

gccctgtcct caccgcggtc cgcccgccgc cgctaaatac ccggatgcgc cgcccaagcg      120

ccagacgcgg agctgggaaa agggaggcag aggaggcgga ggcagaggca gaggcagagg      180

cagagcccga gcccggtgcc gagaccaagc gacagaccgg cggggctggg cctcgcaaag      240

ccggctcggc gagctctccc gacacccgag ccggggagga aaagcagcga ctcctcgctc      300

gcatccccgg gagccgcact ccagactggc ccggtagtca ggggctcagg agcagatccc      360

gaggcaggct ttgctcagcc tccgacgagg gctggccctt tggaaggcgc cttcaacagc      420

cggaccagac aggccaccat gaccgagaat tccacgtccg cccctgcggc caagcccaag      480

cgggccaagg cctccaagaa gtccacagac caccccaagt attcagacat gatcgtggct      540

gccatccagg ccgagaagaa ccgcgctggc tcctcgcgcc agtccattca gaagtatatc      600

aagagccact acaaggtggg tgagaacgct gactcgcaga tcaagttgtc catcaagcgc      660

ctggtcacca ccggtgtcct caagcagacc aaaggggtgg gggcctcggg gtccttccgg      720

ctagccaaga gcgacgaacc caagaagtca gtggccttca agaagaccaa gaaggaaatc      780

aagaaggtag ccacgccaaa gaaggcatcc aagcccaaga aggctgcctc caaagcccca      840

accaagaaac ccaaagccac cccggtcaag aaggccaaga agaagctggc tgccacgccc      900

aagaaagcca aaaaacccaa gactgtcaaa gccaagccgg tcaaggcatc caagcccaaa      960

aaggccaaac cagtgaaacc caaagcaaag tccagtgcca agagggccgg caagaagaag     1020

tgacaatgaa gtcttttctt gcggacactc cctcctgtct cctattttct gtaaataatt     1080

ttctcctttt ttctctcttg atgctcacca ccaccttttg cccccttctg ttctgacttt     1140

ataagagaca ggatttggat tcttcagaaa ttacagaata attcattttt ccttaaccag     1200

ttgtgcaagg acagcaacaa ccaatctaat gatgagaatg tacttatatt ttgttttgct     1260

attaacctac ttacggggtt agggatttgc ggggggggct tgtgtgtttt gttggcttgt     1320

ttgccatgaa ggtagatgtg ggtggggaga agacacaagg cagtttgttc tggctagatg     1380

agagggaacc caggaattgt gaggttagca ggaatatctt tagggtgagt gagttttctt     1440

tgagttgggc acccgttgtg agagtttcag aacctttggc cagcaggaga gaggtggtag     1500

ggagcagcca gccggcaaag gaaggagggg gaaaaaaacc gccaccgggc tgacttccac     1560

ctcccagtgg tgagcagtgg gggcccaaac ccagtttcct tctcattttt gttagtttgc     1620

gctttcggcc tccctatttt cttagggaag gggagtgggg tccaagtgac agctggatgg     1680

gagaagccat agtttctccc agtcagctag gatgtagcca ttgggggatc tttgtggctt     1740

cagcaaattc tcttgttaaa ccggagtgaa aacttcaggg gaagggtggg gagtcagcca     1800

agtgcctcag tgtgccctgt tgaaacttag gtttttccac gcaatcgatg gattgtgtcc     1860

taggaagact tttcttttcc tctggatttt tgttcctcct gtacaagagg tgtctttgct     1920

tggtttggtg gggctgcggc cacttaaaac ctcccgatct ctttttgagt cctttattat     1980

aagtagttgt agctgcggga gggggagggg gagtgggcgg gcagtggata gtaagactta     2040

ctgcagtcga tttgggattt gctaagtagt tttacagagc tagatctgtg tgcatgtgtg     2100

tgtttgtgta tatatacata tctagggcta gtacttagtt tcacacccgg gagctgggag     2160

aaaaaacctg tacagttgtc tttctcttat ttttaataaa atagaaaaat cgcgcacttg     2220

cgcgtccccc ccccaccccc ttttttaaac aagtgttact tgtgccggga aaattttgct     2280

gtctttgtaa ttttaaaact ttaaaataaa ttggaaaagg gagaaactga aaaaaa         2336


<210>  1106
<211>  2336
<212>  DNA
<213>  homo sapiens

<400>  1106
ggaagaaaca cagatggcgg cggcgcagcg ccattccggg ccgggagcag gcagccagca       60

gccctgtcct caccgcggtc cgcccgccgc cgctaaatac ccggatgcgc cgcccaagcg      120

ccagacgcgg agctgggaaa agggaggcag aggaggcgga ggcagaggca gaggcagagg      180

cagagcccga gcccggtgcc gagaccaagc gacagaccgg cggggctggg cctcgcaaag      240

ccggctcggc gagctctccc gacacccgag ccggggagga aaagcagcga ctcctcgctc      300

gcatccccgg gagccgcact ccagactggc ccggtagtca ggggctcagg agcagatccc      360

gaggcaggct ttgctcagcc tccgacgagg gctggccctt tggaaggcgc cttcaacagc      420

cggaccagac aggccaccat gaccgagaat tccacgtccg cccctgcggc caagcccaag      480

cgggccaagg cctccaagaa gtccacagac caccccaagt attcagacat gatcgtggct      540

gccatccagg ccgagaagaa ccgcgctggc tcctcgcgcc agtccattca gaagtatatc      600

aagagccact acaaggtggg tgagaacgct gactcgcaga tcaagttgtc catcaagcgc      660

ctggtcacca ccggtgtcct caagcagacc aaaggggtgg gggcctcggg gtccttccgg      720

ctagccaaga gcgacgaacc caagaagtca gtggccttca agaagaccaa gaaggaaatc      780

aagaaggtag ccacgccaaa gaaggcatcc aagcccaaga aggctgcctc caaagcccca      840

accaagaaac ccaaagccac cccggtcaag aaggccaaga agaagctggc tgccacgccc      900

aagaaagcca aaaaacccaa gactgtcaaa gccaagccgg tcaaggcatc caagcccaaa      960

aaggccaaac cagtgaaacc caaagcaaag tccagtgcca agagggccgg caagaagaag     1020

tgacaatgaa gtcttttctt gcggacactc cctcctgtct cctattttct gtaaataatt     1080

ttctcctttt ttctctcttg atgctcacca ccaccttttg cccccttctg ttctgacttt     1140

ataagagaca ggatttggat tcttcagaaa ttacagaata attcattttt ccttaaccag     1200

ttgtgcaagg acagcaacaa ccaatctaat gatgagaatg tacttatatt ttgttttgct     1260

attaacctac ttacggggtt agggatttgc ggggggggct tgtgtgtttt gttggcttgt     1320

ttgccatgaa ggtagatgtg ggtggggaga agacacaagg cagtttgttc tggctagatg     1380

agagggaacc caggaattgt gaggttagca ggaatatctt tagggtgagt gagttttctt     1440

tgagttgggc acccgttgtg agagtttcag aacctttggc cagcaggaga gaggtggtag     1500

ggagcagcca gccggcaaag gaaggagggg gaaaaaaacc gccaccgggc tgacttccac     1560

ctcccagtgg tgagcagtgg gggcccaaac ccagtttcct tctcattttt gttagtttgc     1620

gctttcggcc tccctatttt cttagggaag gggagtgggg tccaagtgac agctggatgg     1680

gagaagccat agtttctccc agtcagctag gatgtagcca ttgggggatc tttgtggctt     1740

cagcaaattc tcttgttaaa ccggagtgaa aacttcaggg gaagggtggg gagtcagcca     1800

agtgcctcag tgtgccctgt tgaaacttag gtttttccac gcaatcgatg gattgtgtcc     1860

taggaagact tttcttttcc tctggatttt tgttcctcct gtacaagagg tgtctttgct     1920

tggtttggtg gggctgcggc cacttaaaac ctcccgatct ctttttgagt cctttattat     1980

aagtagttgt agctgcggga gggggagggg gagtgggcgg gcagtggata gtaagactta     2040

ctgcagtcga tttgggattt gctaagtagt tttacagagc tagatctgtg tgcatgtgtg     2100

tgtttgtgta tatatacata tctagggcta gtacttagtt tcacacccgg gagctgggag     2160

aaaaaacctg tacagttgtc tttctcttat ttttaataaa atagaaaaat cgcgcacttg     2220

cgcgtccccc ccccaccccc ttttttaaac aagtgttact tgtgccggga aaattttgct     2280

gtctttgtaa ttttaaaact ttaaaataaa ttggaaaagg gagaaactga aaaaaa         2336


<210>  1107
<211>  6330
<212>  DNA
<213>  homo sapiens

<400>  1107
cgcttgttcg ctcactctca gtgaaaagag ttttgaaatg agttctgaat agacagcatt       60

ttctttgtgc ggttggtaaa taacacagag caaagttagc aagttgcagc gcctctgcgt      120

tctgattcta tggaaccttt ttgtagggag aagggcagga tgtttttaac tgaatgtgac      180

ctcaggggaa tactagagaa aataataaaa tttctgaatg gggcagcgtg gagaaatcct      240

aagagaaata gcataagagc attttggaac acatccagga aaagataact ttcgacacac      300

ctgtagacgt tcgccaggta aaggagtgat ggaaactctc cagttcagat ccagtagctt      360

ttagggaagg aactacagtt gctgacttaa gttgaagaag catctattta atgtctggtc      420

aaatcctaca agaaacacag aaatctatga ttaaaaagct gagcactttg atatactgca      480

aagggtagag aaggcaggac ggtagaaatt ttctgcaaga aagaatgaat ttcaggattt      540

atcactaaat aagacaaagt catttattta gtccccctga cacagcaggg caaactgagt      600

tgacatacaa gttacctgga gaaaaagaga gcaattccag gacttcctct tcagcctaaa      660

agaaggtacc agatctgtgc actggggcga tgtggaagag acctgcttat tgcccctgat      720

gtaagctcca gtaagaaaag acgtcaagta caagtactag gaaatcactt tatacatctg      780

tttataggaa tgacctcagg actttgtgtt catgttatag atggatgcag aggctgaaga      840

taaaacgctg cgtactcgct ctaaaggaac cgaggtgcca atggattcac taatccagga      900

gctcagtgtt gcctatgatt gctccatggc aaagaagaga acagctgaag atcaggcttt      960

gggggttcca gtcaacaaaa ggaaatccct gctaatgaag ccccgacact acagcccaaa     1020

agcagactgc caagaagacc gcagtgacag gacagaggac gatggcccct tggaaacaca     1080

tggtcactct accgcagagg aaatcatgat aaaacctatg gatgaaagtc ttctttcaac     1140

tgcacaagaa aactccagta ggaaggaaga cagatactct tgttatcaag agctcatggt     1200

caagtcttta atgcacttgg ggaaatttga aaaaaatgta tctgttcaga ctgtaagtga     1260

aaatttaaat gacagtggca tccagtcttt aaaagcagag agcgatgaag cagacgagtg     1320

ctttctgatt cattctgatg atggaagaga caagattgat gattctcagc cacccttctg     1380

ctcctctgat gacaatgaaa gtaactctga aagtgcagaa aatggctggg acagtggctc     1440

caacttctca gaagaaacca aaccacctag agtcccaaag tatgttttaa cagatcataa     1500

aaaagaccta ttggaagttc ctgaaataaa aactgaaggt gacaaattta tcccttgtga     1560

gaacaggtgt gattctgaaa cagaaaggaa agacccgcag aatgctctcg cagaacccct     1620

ggatggcaat gcccagccct cattccctga cgttgaggag gaagatagcg agagcctggc     1680

agtaatgacg gaagagggta gtgacctgga aaaggccaag gggaatttaa gtttgctgga     1740

gcaggcaatt gctctgcagg ctgagcgagg ttgtgttttc cataacacct acaaagagct     1800

ggataggttc ctgctggagc acctagcagg ggaaaggagg caaaccaaag ttatcgacat     1860

gggtggaaga caaatcttta acaataaaca ttcaccaagg cctgaaaaga gggagaccaa     1920

gtgcccgatc cctggatgtg atggcacggg acacgtgaca gggctctacc cgcaccaccg     1980

cagcctttcg gggtgccccc acaaagtgcg ggttcccctg gaaattcttg ccatgcatga     2040

aaatgtgctc aagtgtccca cgccgggatg cacaggaagg ggtcatgtga acagcaaccg     2100

caacacccac aggagtcttt ctggttgtcc aattgctgca gctgaaaaat tggcaatgtc     2160

ccaggataaa aatcagcttg attctcccca aactgggcag tgtcctgacc aggcccacag     2220

gacaagtttg gtgaagcaaa ttgaattcaa tttcccgtca caagccatca cctctcccag     2280

agccacagtg tcaaaagaac aagagaagtt tggaaaagta ccatttgatt atgccagttt     2340

tgatgcccaa gttttcggta aacgccctct catacaaaca gtgcaaggac gaaaaacacc     2400

accatttcct gaatcaaagc attttccaaa tccagtgaaa tttcctaatc gactgcctag     2460

tgcaggcgcc cacacccaga gccctggccg tgccagctct tatagctacg gtcaatgtag     2520

tgaagacacc cacatagcag cagctgctgc catcctgaac ctttccaccc gctgcaggga     2580

agccacagac atcctctcca acaagccaca gagtctgcat gccaagggag ccgaaataga     2640

agtggatgaa aatggcacat tggacttaag catgaaaaaa aatcgaatcc tggacaagtc     2700

tgcaccccta acttcctcta acacttctat tccaactcct tcctcttccc cattcaaaac     2760

aagcagcatt ctggtcaatg cagcattcta tcaggctctt tgtgaccaag agggctggga     2820

cactcctatc aactatagca aaactcacgg gaagacagag gaggagaaag agaaagaccc     2880

agtgagctct ctagaaaatt tagaggaaaa aaagtttcct ggagaggcct ctataccaag     2940

ccctaaaccc aagcttcatg caagagatct caaaaaggaa ctaatcacct gtccaacacc     3000

aggatgtgat ggaagtggcc acgtgacagg aaactatgca tctcatcgca gtgtttctgg     3060

atgtccttta gcagataaga ctctaaaatc cctcatggct gccaactctc aggagcttaa     3120

gtgtccaacc ccaggctgcg atggctcggg gcacgtgact ggaaactatg cttcccacag     3180

aagcttgtcc ggatgccctc gtgcaaggaa aggtggtgtc aaaatgaccc ctaccaagga     3240

agaaaaagaa gaccctgaac tgaaatgtcc tgtgataggg tgtgatggcc aaggtcacat     3300

atcaggtaaa tacacatcac accgcacagc ttctggctgt cctctggctg ccaagagaca     3360

gaaggagaat cctctcaatg gagcctccct ctcctggaaa ctgaacaaac aagagctacc     3420

acattgtccc ttgccaggct gcaatgggct gggccatgta aataatgttt ttgtcaccca     3480

ccgaagctta tctggatgtc ctctcaatgc acaagttatc aaaaagggca aggtttctga     3540

agaactcatg accatcaagc tcaaagcaac tgggggaata gagagtgatg aagaaattag     3600

gcatttggat gaagaaataa aggaactgaa tgaatccaac cttaaaattg aagcagatat     3660

gatgaaactt cagacccaga tcacatctat ggagagcaac ttaaagacga tagaggagga     3720

gaacaaactc atagaacaga acaatgaaag tctgctgaaa gagctggcag gtctaagcca     3780

agctctcatt tcaagccttg ctgacatcca gcttccacag atgggaccta tcagtgagca     3840

gaattttgaa gcatatgtaa atacactcac agatatgtac agcaatctgg aacgggacta     3900

ttccccggaa tgcaaagctc tactggaaag tatcaaacag gcagtgaagg gtatccatgt     3960

gtaggatcac agcgctgccg ggcaacagaa gttaccaaca gcagtaaact ccagatggat     4020

ctgttagagg ttcatgtact gctaaggcgt ggaggttgcc gtactgcatt tacaatttgc     4080

aacattgcac taattttatt ttccccagct gatataaaaa ggaaagaaaa actatgatag     4140

acttcttgga ttaaaagcaa tgcagtcaat tattagatct tatttatttt catatgtttt     4200

tcttttattt cttcattgta ctcttttttt ttttgtaaag tatatgtaaa ataaatgtga     4260

catttttata atttatttat tactaatcaa agagtttttt atcttttaac tgcattttga     4320

agtctgccgt atttttacaa gtgtgtttat taatttattt tccaatagga tttaaataga     4380

aatgctattc tcaagtcatc tttcttgctg ggttttaatg aggaaacagg aaagggtgaa     4440

ggaaatcctt gtctaaggac tgcactatag ttgagtttga tttttattgc acacttcttc     4500

ccccaccttt cactgatttt tgtatttata aatgaatttg cggtaaggtg agctgcacgg     4560

aaggaataag aagacaaatg gcgcccacta gtggggaatc cgcactcaca aaagcacagg     4620

atgctggaaa acagcctgct cagaatttgt tagcaataat taaatatagc aatcagcaaa     4680

gtattcgact tggctggacg gttttcgtta atatgaatta tttatttgaa atgttttaaa     4740

gaaacataag cctttttagt gatgcagatt tgtctgtttg tttttcaagt catatcagat     4800

cgttggcaac tcgtatccca agatgaaaaa taagacttgg tgtgaccagc caggctttcc     4860

tgccatatgt tggtacaata tacaagtgac aatattggtg tagatttgta cttagcaaat     4920

acaaacacat ccaaatgaaa aattttgtag ataccatatc ccctgaaata gcatttatct     4980

tactgggttg actggaaagg aatggaaaat atagtaacac atgaaaaaat gctactccaa     5040

tctgaatgat tacttcaaac actggcacct tgggtctcac ccaccatagg aaacaagaca     5100

acattcaatt tgatagaaat cttgccacaa aacttcaaat gctacaaaat atacacacac     5160

actcacacac acaggcatac tcacacacag acacacacac acacacacac acagactcat     5220

ccacacttca aattgagccc acaatcttga atttctgaac ggatcagagt ttcatagttt     5280

ctatagtaaa ggcaatgtct atttcaggga ttgtaaagta gttaagcatt gtttcaaaag     5340

tttttttata tttatttttt ttaaggaaaa ggtatagaca accagctaaa ctgccttttt     5400

ggtgtgcaca cacatttcat gtgcagacgt gcctctgtgt aaatgtacac atgaacttca     5460

tgtgggctta attttctgtg ctataaacaa aagtgtttat tttttattaa cctcatggat     5520

atttagatgg aaagtgatgg cattcacagg cttgatgtat tccactgtta ttactgttac     5580

ctgcacaaat gaaaaacaat actcaacagt aattccactc ccatgaaact ttggtcattg     5640

ttatgcatta agtggggctt atctttggtt tggagttcat ttgaactctt gaaccttagt     5700

ttagtgaaga tgaactgtct gttcttaggt agaaacggtg tttatttaaa aatcagtttt     5760

aaaaaatgag ctaccatatg tgctgtctat tataaatggg acaccaaaca aaattttcta     5820

ttacagttgt gtacttgcaa acattttgct atacagtact tcatagatgc atacaaatga     5880

gctcacttat tacaaagaca aacgtttaat ttgctaaata ttttaacaag tttgttatat     5940

attttattta atttaaaaga aatctcttac caacctacat atttattact ataatttgct     6000

atgacttcag gttaatttat ttgtgtttgc atagtttgag caggatgttt tgtgaagtat     6060

gtttgtattt atttgcctac tttgtacttg atgtgttttg taatgtgcac tgaatttgtt     6120

ttcttttcaa ctatgttaat gatcaatact gtaaattggg tcttttgtaa acaaaaaggc     6180

aatgatgtat gcattttttt taatttgagg tagtttgttt gtatactgtt tctccaaaca     6240

cttaatattt cttacatcaa agcaacaaaa ttgtgttcag tgctgtacat ttggtgtatg     6300

gtaggaaata aaaattgata acgagttttg                                      6330


<210>  1108
<211>  6330
<212>  DNA
<213>  homo sapiens

<400>  1108
cgcttgttcg ctcactctca gtgaaaagag ttttgaaatg agttctgaat agacagcatt       60

ttctttgtgc ggttggtaaa taacacagag caaagttagc aagttgcagc gcctctgcgt      120

tctgattcta tggaaccttt ttgtagggag aagggcagga tgtttttaac tgaatgtgac      180

ctcaggggaa tactagagaa aataataaaa tttctgaatg gggcagcgtg gagaaatcct      240

aagagaaata gcataagagc attttggaac acatccagga aaagataact ttcgacacac      300

ctgtagacgt tcgccaggta aaggagtgat ggaaactctc cagttcagat ccagtagctt      360

ttagggaagg aactacagtt gctgacttaa gttgaagaag catctattta atgtctggtc      420

aaatcctaca agaaacacag aaatctatga ttaaaaagct gagcactttg atatactgca      480

aagggtagag aaggcaggac ggtagaaatt ttctgcaaga aagaatgaat ttcaggattt      540

atcactaaat aagacaaagt catttattta gtccccctga cacagcaggg caaactgagt      600

tgacatacaa gttacctgga gaaaaagaga gcaattccag gacttcctct tcagcctaaa      660

agaaggtacc agatctgtgc actggggcga tgtggaagag acctgcttat tgcccctgat      720

gtaagctcca gtaagaaaag acgtcaagta caagtactag gaaatcactt tatacatctg      780

tttataggaa tgacctcagg actttgtgtt catgttatag atggatgcag aggctgaaga      840

taaaacgctg cgtactcgct ctaaaggaac cgaggtgcca atggattcac taatccagga      900

gctcagtgtt gcctatgatt gctccatggc aaagaagaga acagctgaag atcaggcttt      960

gggggttcca gtcaacaaaa ggaaatccct gctaatgaag ccccgacact acagcccaaa     1020

agcagactgc caagaagacc gcagtgacag gacagaggac gatggcccct tggaaacaca     1080

tggtcactct accgcagagg aaatcatgat aaaacctatg gatgaaagtc ttctttcaac     1140

tgcacaagaa aactccagta ggaaggaaga cagatactct tgttatcaag agctcatggt     1200

caagtcttta atgcacttgg ggaaatttga aaaaaatgta tctgttcaga ctgtaagtga     1260

aaatttaaat gacagtggca tccagtcttt aaaagcagag agcgatgaag cagacgagtg     1320

ctttctgatt cattctgatg atggaagaga caagattgat gattctcagc cacccttctg     1380

ctcctctgat gacaatgaaa gtaactctga aagtgcagaa aatggctggg acagtggctc     1440

caacttctca gaagaaacca aaccacctag agtcccaaag tatgttttaa cagatcataa     1500

aaaagaccta ttggaagttc ctgaaataaa aactgaaggt gacaaattta tcccttgtga     1560

gaacaggtgt gattctgaaa cagaaaggaa agacccgcag aatgctctcg cagaacccct     1620

ggatggcaat gcccagccct cattccctga cgttgaggag gaagatagcg agagcctggc     1680

agtaatgacg gaagagggta gtgacctgga aaaggccaag gggaatttaa gtttgctgga     1740

gcaggcaatt gctctgcagg ctgagcgagg ttgtgttttc cataacacct acaaagagct     1800

ggataggttc ctgctggagc acctagcagg ggaaaggagg caaaccaaag ttatcgacat     1860

gggtggaaga caaatcttta acaataaaca ttcaccaagg cctgaaaaga gggagaccaa     1920

gtgcccgatc cctggatgtg atggcacggg acacgtgaca gggctctacc cgcaccaccg     1980

cagcctttcg gggtgccccc acaaagtgcg ggttcccctg gaaattcttg ccatgcatga     2040

aaatgtgctc aagtgtccca cgccgggatg cacaggaagg ggtcatgtga acagcaaccg     2100

caacacccac aggagtcttt ctggttgtcc aattgctgca gctgaaaaat tggcaatgtc     2160

ccaggataaa aatcagcttg attctcccca aactgggcag tgtcctgacc aggcccacag     2220

gacaagtttg gtgaagcaaa ttgaattcaa tttcccgtca caagccatca cctctcccag     2280

agccacagtg tcaaaagaac aagagaagtt tggaaaagta ccatttgatt atgccagttt     2340

tgatgcccaa gttttcggta aacgccctct catacaaaca gtgcaaggac gaaaaacacc     2400

accatttcct gaatcaaagc attttccaaa tccagtgaaa tttcctaatc gactgcctag     2460

tgcaggcgcc cacacccaga gccctggccg tgccagctct tatagctacg gtcaatgtag     2520

tgaagacacc cacatagcag cagctgctgc catcctgaac ctttccaccc gctgcaggga     2580

agccacagac atcctctcca acaagccaca gagtctgcat gccaagggag ccgaaataga     2640

agtggatgaa aatggcacat tggacttaag catgaaaaaa aatcgaatcc tggacaagtc     2700

tgcaccccta acttcctcta acacttctat tccaactcct tcctcttccc cattcaaaac     2760

aagcagcatt ctggtcaatg cagcattcta tcaggctctt tgtgaccaag agggctggga     2820

cactcctatc aactatagca aaactcacgg gaagacagag gaggagaaag agaaagaccc     2880

agtgagctct ctagaaaatt tagaggaaaa aaagtttcct ggagaggcct ctataccaag     2940

ccctaaaccc aagcttcatg caagagatct caaaaaggaa ctaatcacct gtccaacacc     3000

aggatgtgat ggaagtggcc acgtgacagg aaactatgca tctcatcgca gtgtttctgg     3060

atgtccttta gcagataaga ctctaaaatc cctcatggct gccaactctc aggagcttaa     3120

gtgtccaacc ccaggctgcg atggctcggg gcacgtgact ggaaactatg cttcccacag     3180

aagcttgtcc ggatgccctc gtgcaaggaa aggtggtgtc aaaatgaccc ctaccaagga     3240

agaaaaagaa gaccctgaac tgaaatgtcc tgtgataggg tgtgatggcc aaggtcacat     3300

atcaggtaaa tacacatcac accgcacagc ttctggctgt cctctggctg ccaagagaca     3360

gaaggagaat cctctcaatg gagcctccct ctcctggaaa ctgaacaaac aagagctacc     3420

acattgtccc ttgccaggct gcaatgggct gggccatgta aataatgttt ttgtcaccca     3480

ccgaagctta tctggatgtc ctctcaatgc acaagttatc aaaaagggca aggtttctga     3540

agaactcatg accatcaagc tcaaagcaac tgggggaata gagagtgatg aagaaattag     3600

gcatttggat gaagaaataa aggaactgaa tgaatccaac cttaaaattg aagcagatat     3660

gatgaaactt cagacccaga tcacatctat ggagagcaac ttaaagacga tagaggagga     3720

gaacaaactc atagaacaga acaatgaaag tctgctgaaa gagctggcag gtctaagcca     3780

agctctcatt tcaagccttg ctgacatcca gcttccacag atgggaccta tcagtgagca     3840

gaattttgaa gcatatgtaa atacactcac agatatgtac agcaatctgg aacgggacta     3900

ttccccggaa tgcaaagctc tactggaaag tatcaaacag gcagtgaagg gtatccatgt     3960

gtaggatcac agcgctgccg ggcaacagaa gttaccaaca gcagtaaact ccagatggat     4020

ctgttagagg ttcatgtact gctaaggcgt ggaggttgcc gtactgcatt tacaatttgc     4080

aacattgcac taattttatt ttccccagct gatataaaaa ggaaagaaaa actatgatag     4140

acttcttgga ttaaaagcaa tgcagtcaat tattagatct tatttatttt catatgtttt     4200

tcttttattt cttcattgta ctcttttttt ttttgtaaag tatatgtaaa ataaatgtga     4260

catttttata atttatttat tactaatcaa agagtttttt atcttttaac tgcattttga     4320

agtctgccgt atttttacaa gtgtgtttat taatttattt tccaatagga tttaaataga     4380

aatgctattc tcaagtcatc tttcttgctg ggttttaatg aggaaacagg aaagggtgaa     4440

ggaaatcctt gtctaaggac tgcactatag ttgagtttga tttttattgc acacttcttc     4500

ccccaccttt cactgatttt tgtatttata aatgaatttg cggtaaggtg agctgcacgg     4560

aaggaataag aagacaaatg gcgcccacta gtggggaatc cgcactcaca aaagcacagg     4620

atgctggaaa acagcctgct cagaatttgt tagcaataat taaatatagc aatcagcaaa     4680

gtattcgact tggctggacg gttttcgtta atatgaatta tttatttgaa atgttttaaa     4740

gaaacataag cctttttagt gatgcagatt tgtctgtttg tttttcaagt catatcagat     4800

cgttggcaac tcgtatccca agatgaaaaa taagacttgg tgtgaccagc caggctttcc     4860

tgccatatgt tggtacaata tacaagtgac aatattggtg tagatttgta cttagcaaat     4920

acaaacacat ccaaatgaaa aattttgtag ataccatatc ccctgaaata gcatttatct     4980

tactgggttg actggaaagg aatggaaaat atagtaacac atgaaaaaat gctactccaa     5040

tctgaatgat tacttcaaac actggcacct tgggtctcac ccaccatagg aaacaagaca     5100

acattcaatt tgatagaaat cttgccacaa aacttcaaat gctacaaaat atacacacac     5160

actcacacac acaggcatac tcacacacag acacacacac acacacacac acagactcat     5220

ccacacttca aattgagccc acaatcttga atttctgaac ggatcagagt ttcatagttt     5280

ctatagtaaa ggcaatgtct atttcaggga ttgtaaagta gttaagcatt gtttcaaaag     5340

tttttttata tttatttttt ttaaggaaaa ggtatagaca accagctaaa ctgccttttt     5400

ggtgtgcaca cacatttcat gtgcagacgt gcctctgtgt aaatgtacac atgaacttca     5460

tgtgggctta attttctgtg ctataaacaa aagtgtttat tttttattaa cctcatggat     5520

atttagatgg aaagtgatgg cattcacagg cttgatgtat tccactgtta ttactgttac     5580

ctgcacaaat gaaaaacaat actcaacagt aattccactc ccatgaaact ttggtcattg     5640

ttatgcatta agtggggctt atctttggtt tggagttcat ttgaactctt gaaccttagt     5700

ttagtgaaga tgaactgtct gttcttaggt agaaacggtg tttatttaaa aatcagtttt     5760

aaaaaatgag ctaccatatg tgctgtctat tataaatggg acaccaaaca aaattttcta     5820

ttacagttgt gtacttgcaa acattttgct atacagtact tcatagatgc atacaaatga     5880

gctcacttat tacaaagaca aacgtttaat ttgctaaata ttttaacaag tttgttatat     5940

attttattta atttaaaaga aatctcttac caacctacat atttattact ataatttgct     6000

atgacttcag gttaatttat ttgtgtttgc atagtttgag caggatgttt tgtgaagtat     6060

gtttgtattt atttgcctac tttgtacttg atgtgttttg taatgtgcac tgaatttgtt     6120

ttcttttcaa ctatgttaat gatcaatact gtaaattggg tcttttgtaa acaaaaaggc     6180

aatgatgtat gcattttttt taatttgagg tagtttgttt gtatactgtt tctccaaaca     6240

cttaatattt cttacatcaa agcaacaaaa ttgtgttcag tgctgtacat ttggtgtatg     6300

gtaggaaata aaaattgata acgagttttg                                      6330


<210>  1109
<211>  1025
<212>  DNA
<213>  homo sapiens

<400>  1109
gtttgttcct aaatctaatc gagctcccaa ggaactagta tcttatagaa cacacataga       60

aaatagtgct ctacagtagt cactttcaca tttttttctt ggatccaact tcatgataag      120

aaatacattt taactcataa tctattcaca tgtatatgaa taactgaaac agaagtttca      180

caaaattatg attatgtttg ccacaaatgg tgtgctctaa tattttcctt ctgtttcatc      240

agaagaaaaa tactggttac tatccagcta agctgatttt gtgacccatt aatgagtttc      300

agttctcact ttgaaaacac tgttctagaa ttacagaaag gtctagggat gagaactaac      360

accactgtgc atcacagtgt gtcagtctgt gccaggcagc ttataaatat tttttgcctc      420

taatttttat acatttatga ggtaagtatc attttctagg taaggatgct aatctgtctc      480

caagccaaat aacacacagt aaatcatggc accaggattt gaatctgggt ctttatacat      540

catagcccat gctgttctca ctgtattttg ctttttccaa gtataacccc gttttcacac      600

gaatggcccc ttcacatatt tgaagactac cgtcgtgtcc gtgctgaccc tttctccctg      660

ccacacatgg ctggagtgca atggcgcgat ctcggctcac tgcaacctct gtctcccagg      720

ttcaggaaaa tggctttgta aagaagcttg agcctaaatc tggctggatg acttttctag      780

aagttacagg aaagatctgt gaaatgctct tctgtcctga agcaatactg ttgaccagaa      840

aggacactcc atattgtgaa accggcctaa tttttctgac tcttacgaaa acgattgcca      900

acacatactt ctacttttaa ataaacaact ttgatgatgt aacttgacct tccagagtta      960

cagaaatttt gtccctattt aatgaataaa ttgtatgtat ttttctctat aaaaaaaaaa     1020

aaaaa                                                                 1025


<210>  1110
<211>  5809
<212>  DNA
<213>  homo sapiens

<400>  1110
aaaggggggg aacctagagt cggtgggggg gaagcgatgt ttgcccgtca gtcgagtccg       60

gagtgaggag ctcggtcgcc gaagcggagg gagactcttg agcttcatct tgccgccgcc      120

acggccaccg cctggacctt tgcccggagg gagctgcaga gggtccatcg ccgccgtcct      180

ctggagggca gcgcgattgg gggcccggac ctccagtccg ggggggattt ttcgtcgtcc      240

ccctcccccc aaccagggag cccgagcggc cgccaaacaa aggtaccagt cgccgccgcg      300

ggaggaggag gagccggagc ctctgcctca gcagccgctg gacccgccgc ccttcttccc      360

catctctccc ccgggcctgc tggttttggg ggggagaagg agagagggga ctctggacgt      420

gccagggtca gatctcgcct ccgaggaagg tgcagctgaa cctggtgttt tagaggatac      480

cttggtccca gagtcatcat gaaggccctt gatgagcctc cctatttgac agtgggcact      540

gatgtgagtg ctaaatacag aggagccttt tgtgaagcca agatcaagac agcaaaaaga      600

cttgtcaaag tcaaggtgac atttagacat gattcttcaa cagtggaagt tcaggatgac      660

cacataaagg gcccactaaa ggtaggagct attgtggaag tgaagaatct tgatggtgca      720

tatcaggaag ctgttatcaa taaactaaca gatgcgagtt ggtacactgt agtttttgat      780

gacggagatg agaagacact gagacgatct tcactgtgcc tgaaaggaga gaggcatttt      840

gctgaaagtg aaacattaga ccagctccca ctcaccaacc ctgagcattt tggcactcca      900

gtcataggaa agaaaacaaa tagaggaaga agatctaatc atataccaga ggaagagtct      960

tcatcatcct ccagtgatga agatgaggat gataggaaac agattgatga gctactaggc     1020

aaagttgtat gtgtagatta cattagtttg gataaaaaga aagcactgtg gtttcctgca     1080

ttggtggttt gtcctgattg tagtgatgag attgctgtaa aaaaggacaa tattcttgtt     1140

cgatctttca aagatggaaa atttacttca gttccaagaa aagatgtcca tgaaattact     1200

agtgacactg caccaaagcc tgatgctgtt ttaaagcaag cctttgaaca ggcacttgaa     1260

tttcacaaaa gtagaactat tcctgctaac tggaagactg aattgaaaga agatagctct     1320

agcagtgaag cagaggaaga agaggaggag gaagatgatg aaaaagaaaa ggaggataat     1380

agcagtgaag aagaagaaga aatagaacca tttccagaag aaagggagaa ctttcttcag     1440

caattgtaca aatttatgga agatagaggt acacctatta acaaacgacc tgtacttgga     1500

tatcgaaatt tgaatctctt taagttattc agacttgtac acaaacttgg aggatttgat     1560

aatattgaaa gtggagctgt ttggaaacaa gtctaccaag atcttggaat ccctgtctta     1620

aattcagctg caggatacaa tgttaaatgt gcttataaaa aatacttata tggttttgag     1680

gagtactgta gatcagccaa cattgaattt cagatggcat tgccagagaa agttgttaac     1740

aagcaatgta aggagtgtga aaatgtaaaa gaaataaaag ttaaggagga aaatgaaaca     1800

gagatcaaag aaataaagat ggaggaggag aggaatataa taccaagaga agaaaagcct     1860

attgaggatg aaattgaaag aaaagaaaat attaagccct ctctgggaag taaaaagaat     1920

ttattagaat ctatacctac acattctgat caggaaaaag aagttaacat taaaaaacca     1980

gaagacaatg aaaatctgga tgacaaagat gatgacacaa ctagggtaga tgaatccctc     2040

aacataaagg tagaagctga ggaagaaaaa gcaaaatctg gatacgatga atggattaaa     2100

gcagataaaa tagtaagacc tgctgataaa aatgtgccaa agataaaaca tcggaagaaa     2160

ataaagaata aattagacaa agaaaaagac aaagatgaaa aatactctcc aaaaaactgt     2220

aaacttcggc gcttgtccaa accaccattt cagacaaatc catctcctga aatggtatcc     2280

aaactggatc tcactgatgc caaaaactct gatactgctc atattaagtc catagaaatt     2340

acttcgatcc ttaatggact tcaagcttct gaaagttctg ctgaagacag tgagcaggaa     2400

gatgagagag gtgctcaaga catggataat aatggcaaag aggaatctaa gattgatcat     2460

ttgaccaaca acagaaatga tcttatttca aaggaggaac agaacagttc atctttgcta     2520

gaagaaaaca aagttcatgc agatttggta atatccaaac cagtgtcaaa atctccagaa     2580

agattaagga aagatataga agtattatcc gaagatactg attatgaaga agatgaagtc     2640

acaaaaaaga gaaaggatgt caagaaggac acaacagata aatcttcaaa accacaaata     2700

aaacgtggta aaagaaggta ttgcaataca gaagagtgtc taaaaactgg atcacctggc     2760

aaaaaggaag agaaggccaa gaacaaagaa tcactttgca tggaaaacag tagcaacagc     2820

tcttcagatg aagatgaaga agaaacaaaa gcaaagatga caccaactaa gaaatacaat     2880

ggtttggagg aaaaaagaaa atctctacgg acaactggtt tctattcagg attttcagaa     2940

gtggcagaaa aaaggattaa acttttaaat aactctgatg aaagacttca aaacagcagg     3000

gccaaagatc gaaaagatgt ctggtcaagt attcagggac agtggcctaa aaaaacgctg     3060

aaagagcttt tttcagactc tgatactgag gctgcagctt ccccaccgca tcctgcccca     3120

gaggaggggg tggcagagga gtcactgcag actgtggctg aagaggagag ttgttcaccc     3180

agtgtagaac tagaaaaacc acctccagtc aatgtcgata gtaaacccat tgaagaaaaa     3240

acagtagagg tcaatgacag aaaagcagaa tttccaagta gtggcagtaa ttcagtgcta     3300

aatacccctc ctactacacc tgaatcgcct tcatcagtca ctgtaacaga aggcagccgg     3360

cagcagtctt ctgtaacagt atcagaacca ctggctccaa accaagaaga ggttcgaagt     3420

atcaagagtg aaactgatag cacaattgag gtggatagtg ttgctgggga gctccaagac     3480

ctccagtctg aagggaatag ctcgccagca ggttttgatg ccagtgtgag ctcaagcagt     3540

agtaatcagc cagaaccaga acatcctgaa aaagcctgta caggtcagaa aagagtgaaa     3600

gatgctcagg gaggaggaag ttcatcaaaa aagcagaaaa gaagccataa agcaacagtg     3660

gtaaacaaca aaaagaaggg aaaaggcaca aatagtagtg atagtgaaga actttcagct     3720

ggtgaaagta taactaagag tcagccagtc aaatcagttt ccactggaat gaagtctcat     3780

agtaccaaat ctcccgcaag gacgcagtct ccaggaaaat gtggaaagaa tggtgataag     3840

gatcctgatc tcaaggaacc cagtaatcga ttacccaaag tttacaaatg gagttttcag     3900

atgtcggacc tggaaaatat gacaagtgcc gaacgcatca caattcttca agaaaaactt     3960

caagaaatca gaaaacatta tctgtcatta aaatctgaag tagcttccat tgatcggagg     4020

agaaagcgtt taaagaagaa agagagagaa agtgctgcta catcctcatc ctcctcttca     4080

ccttcatcca gttccataac agctgctgtt atgttaactt tagctgaacc gtcaatgtcc     4140

agcgcatcac aaaatggaat gtcagttgag tgcaggtgac agcaggactt gctaaagcac     4200

tttgcactta atggctgttg agggccactt tttttttata ctgcacagtg gcacaaaaaa     4260

atatcagaca agcactattt tatatttaaa aattgtttct tgacaagctg acttggcact     4320

taagtgcact tttttatgaa gaaaaagtac aatgaactgc ttttcctcaa gcaataattg     4380

tttccaactt gtctgggaat tgtgtgtctg gtaactggaa ggccttccac tgtggcaaat     4440

ggaggctttt cactgcctgt agagacaata cagtaagcat agttaagggg tgggtcagaa     4500

catgttaaga taacttactg tatatgtatt cccttgtatt ttgttaaagc tggaacattt     4560

gatatttttc catttattta tgaaaaaata tgaacctatt ttcatttgta caaggtaatt     4620

gttttttaaa gcaagtcacc ttagggtggc tttaattgta taagtcaagc acatgtaata     4680

aattcaaaac ctgcagttaa caggatatta gacatcaatc ctggtaacca aatattaaag     4740

attctcttta aaaaagactg aacatgttta caggtttgaa ttaggctaaa aggtcttgca     4800

gtggcttttc atggcccttc aaattggaat ggaactactg tactttgcca tttttctata     4860

aatcagtatt tttttttaat tttgatatac attgtgtgaa aaaagaaaat ggctaataaa     4920

ctgtattaaa tcttaaacaa tgtataaaga ttgtacttag ccagttcaaa gtgtatattt     4980

attcataatg aattataaca gttatatttt tgtgttttct tgtaaatgtt tcttttccct     5040

taaatacaga taattcattt gtattgctta ttttattatg agctacaaca aaaggacttc     5100

aggaacaagt aatgtattag tatggttcaa gattgttgat aggaactgtc tcaaaaggat     5160

ggtggttatt ttaaatataa atagctaatg ggggtggtag gcctataaaa ttaaatgcct     5220

tgtataaaat ccaaaatgaa tgcaaaattg ttttcacttg tattgacttt atgttgtatg     5280

attccaatct ctgttctgtt tggcacttgt atttaattct tcacctttgt aagacatttg     5340

tatattgtgg atgtgttcat tcaagctatt taatatctgg cactgttaat acacagtact     5400

ttattgtaca gactgtttta ctgttttaat tgtagttctg tgtacttttt ttggatgggg     5460

ctggcatgtt ttctttgttt cctggcaata cgacgtggga atttcaatgc gttttgttgt     5520

agatgctaac gtgtcagaat cctttacatt caacttttct aagaaaagca ttttcagtct     5580

tgtagtgtgt gcttacagta actaattttg ttgaaaatgg tttcaagtta ttcaaatttg     5640

tacaggactg taaagatttg ttgacagcaa aatgttgaag aaaaaagctt atagaataaa     5700

agctataaag tatatattag gatctgcaaa caatgaagaa ttatgtaata tattgtacaa     5760

atgtaagcaa aggctctgaa ataaaatgcc atagtttgtg aatccttga                 5809


<210>  1111
<211>  1496
<212>  DNA
<213>  homo sapiens

<400>  1111
ggcggctgct gaacggcgga gtggcgtgga cctcatgtag caatgacaat ggaaggggcc       60

agcgggtcga gttttggaat agacacgatt ttgtccagtg ccagttcagg cagcccaggc      120

atgatgaatg gagatttccg cccgctcggt gaggccagga ccgcggattt taggagtcag      180

gccaccccat ctccctgttc ggagattgat accgtaggga cggcgccttc ttctcctatc      240

tcagtcacca tggagccccc ggagccgcat ctggtagcag acgcgaccca gcatcatcac      300

cacctccacc acagccagca gccgccgccg ccggccgcgg ccccgacgca aagtttgcag      360

cctttgcccc aacagcagca gccgctgccg ccacagcagc cgccgccgcc gcccccccag      420

cagctgggct cggccgcctc ggcccccagg acttccacgt cttctttttt aattaaggac      480

atcttgggcg acagcaaacc tctggcggca tgtgcaccct acagcaccag cgtatcctct      540

ccccaccaca ccccgaagca ggagagcaac gcagtgcacg agagcttcag gccaaagctc      600

gagcaggagg acagcaagac caaactcgac aagcgggagg attcccagag cgacatcaaa      660

tgccacggga caaaggagga aggagaccgg gagattacga gtagccgtga gagtccccct      720

gtgagagcca agaagcctcg aaaagcaagg acagcttttt ccgaccacca gctcaatcaa      780

ctggagcgta gctttgagcg gcagaagtac ctgagcgtgc aggatcgcat ggacctggct      840

gcagcgctca acctcactga cacccaagtc aagacctggt accagaaccg caggaccaag      900

tggaagcggc agacagcggt gggcctggag ttgctggccg aggcagggaa ctactcggcg      960

ctgcagagga tgtttccatc gccttatttc tatcacccaa gcctgctggg cagcatggac     1020

agcactacgg cggcggcggc tgccgctgcc atgtacagca gcatgtaccg gactcctcca     1080

gcaccccatc cccagctgca gcggcccctg gtgccccgtg tgctcatcca cggcctaggg     1140

cctgggggac agccagccct taatccattg tccagcccca tcccaggcac cccacacccc     1200

cggtgaaaac attgcagcga aggcactgca atcccttccc catatccctg cccaacccgg     1260

actgctgccc gtcctctccc tgctccaggc cactaggcct cccttgcagc caactctgga     1320

aggcagagga gtaagagagg aagatgctta ccagtgggca ggggaccccc aaagaggagc     1380

cagccctctg ctctccatct ccccacccct agaaacaggg ctggaaatct cccccacagc     1440

agtgtgactg gtgaaaatgc tgaccccaca cagagtgcaa ccagtaagtg aaaaca         1496


<210>  1112
<211>  2635
<212>  DNA
<213>  homo sapiens

<400>  1112
aggatgctcg ggcggcggct gcagtgggac ctccaccttc tctgccaacc agagcggagg       60

aacctttccg cctccctcca agcggcgcac tgagcgctct ttgcctagaa cgacttccct      120

cccgctgcct ggggcagcct caccctgggc gcccacaccc cagccctggg agagcgctac      180

tccgcctccc gcaccaccga aaacctcctc ctcctttacg ggccgcgcct cctttacggg      240

ccgcgccccc tttatacgcg gacgcgccct cttttggtcg ccccctcccc aacccagcac      300

taaggagcac cctgctctgg tctccgccac cacccagcgc ctcctggacc catcccccca      360

aacccttgaa cgtcctcagg acccccaggc tgcagcctcg gagctcccgg aacgatggtg      420

aagttgggga acaatttcgc agagaagggc accaagcagc cgctgctgga ggatggcttc      480

gacaccattc ccctgatgac gcccctcgat gtcaatcagc tgcagttccc gcccccggat      540

aaggtggtcg tgaaaactaa gaccgagtat gaacctgacc gcaagaaagg gaaagcacgt      600

cctccccaaa ttgctgagtt caccgtcagc atcacggagg gtgtcaccga gaggtttaag      660

gtctccgtgt tggtcctctt cgccctggcc ttcctcacct gcgtcgtctt cctggttgtc      720

tacaaggtgt acaagtatga ccgcgcctgc cccgatgggt tcgtcctcaa gaacacccag      780

tgcatcccag aaggcttgga gagctactac gcggagcaag actccagtgc ccgggagaaa      840

ttttacacag tcataaacca ctacaacctg gccaagcaga gcatcacgcg ctccgtatcg      900

ccctggatgt cagttctgtc agaagagaag ctgtccgagc aggagactga agcggctgag      960

aagtcagctt agcgggatgg gcaagttcct tacaatgtgt cacttgcaaa taacaaaggg     1020

actttgaggg acatttcatt aaatataatt actgatactt tagaggttac tcatttacgg     1080

tgcaattgct tctgtttgct aatgctgctt tgcaaataaa acttgctgcc gaccacccac     1140

gggcataaaa tcaagtgcat ttcagcattg cctaaagagc tctgacacca cttttcatgt     1200

taagatcttc atttagctcc tttactggga tttattggat gctgtaaaaa aataaattta     1260

cactggatat gcgaagggtt tggatctcag ataaatgcat tttgtggaat tgattttctg     1320

aaccgaccct gctgtctgca aaccttcctc catagccata tctagagtga tctctcgctg     1380

tgctaagagc aagcctactt cgcatttctt cctcggccat cagcgggtaa cagtgctgac     1440

tgctgccaag gtgcactgta gtaagtaagt ggcatagaga acgaggaaaa agaccccccc     1500

acccctccct gtgctgactc ctgagtcggg gtgggacggc cctgcaatgt ggcaggctcg     1560

gtgtggattg actactccct cccctctgac tctggcatct tggtaaggag ggaggggcac     1620

cacccatctg ggtggagaca gctggggttt gctccagtgt gtgtagactg gcagagcatg     1680

tgagggagag ggctgggaag agacggccct gggcccgtga ggtgcagaac tctccctgca     1740

ggtagtctgt ctgctctgtg atgtgctgat aggaaagagc ccccactggc cctctggttc     1800

acttctatta tgaataaatt tgcaccaata gccccattag tttttaaaga aatgagctgg     1860

gtgggaaaag tggaaatgta atttctggta agcttgagct actttaattt ttattctatg     1920

aaactgatat cccttgatgt gggaaacagg caggaaaggc tgtggggtgg gggtggggga     1980

ctggtgtggc accgtgcaaa caaaatgaca aatttcaact cacaatcttt gtaagaaaat     2040

tgttccagtt tgaatcttga tattaaagtt tatgtttaca aaactgccag ttagatgaac     2100

taagtgtgta aaacaaatag aaaagacatt cgcagacatt tcttctatgt tattgaatgt     2160

gttgtttctg gtgtacgtgt caaaagtttc agttttttag atcagaaata aacgacaaat     2220

agtgtgagat gtgttgtgaa caggcatggt gaccgtggtc agcgccactc ttgtttcctg     2280

aaatgtgctt ctaagacaga aaatgtattt tctcatcaag ggtgtctgga gacacagacc     2340

gtgaccttgg cgcagcggtg tgcatcagag gcgtgtgctg agaagggtgg tgttaagctg     2400

tggaaaatga ctcaagagca ataaatcagt gccaaagctt ccctgcgcat ctgaatagac     2460

acaagtgaag cccgtgtgcg cacagtgcag aggccgagcc tgtatttcca ggtagacgtg     2520

gactttattg actgtgaatt catttacatg taacttctga catttcactc tgtgcaaata     2580

aagaacatga ggataaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa          2635


<210>  1113
<211>  2078
<212>  DNA
<213>  homo sapiens

<400>  1113
gcgtgatcca ctccttttcc tctaagaatg ctgaacggta ccactctaga ggcagccatg       60

ctctttcacg ggatctccgg aggccacatc caaggcatca tggaggagat ggagcgcaga      120

tccaagactg aggcccgtct ggccaaaggc gcccagctca acggccgcga cgcgggcatg      180

cccccgctca gcccggagaa gcccgccctg tgcgccggct gcgggggcaa gatctcggac      240

aggtactatc tgctggctgt ggacaaacag tggcatctga gatgcctgaa gtgctgtgaa      300

tgtaagctgg ccctcgagtc cgagctcacc tgctttgcca aggacggtag catttactgc      360

aaggaggatt actacagaag gttctctgtg cagagatgtg cccgctgcca ccttggcatt      420

tccgcctcgg agatggtcat gcgcgcccga gactctgtct accacctgag ctgcttcacc      480

tgctccactt gcaacaagac tctgaccacg ggcgaccatt tcggcatgaa ggacagcctg      540

gtgtactgcc gcgcccactt cgagaccctc ttgcaaggag agtatccacc gcagctgagc      600

tacacggagc tggcggccaa gagcggcggc ctggccctgc cttacttcaa cggtacgggc      660

accgtgcaga aagggcggcc ccggaagcgg aagagcccag cgctgggagt ggacatcgtc      720

aattacaact caggttgtaa tgagaatgag gcagaccact tggaccggga ccagcagcct      780

tatccaccct cgcagaagac caagcgcatg cgaacctctt tcaagcatca ccagctccgg      840

accatgaaat cctactttgc catcaaccac aacccggatg ccaaggacct caagcagctt      900

gcccagaaaa caggtctgac caaaagagtt ttgcaggttt ggttccaaaa cgcacgagcc      960

aaattcagaa ggaacctttt gcggcaggag aatgggggtg ttgataaagc tgacggcacg     1020

tcgcttccgg ccccgccctc agcagacagc ggagctctca ctccacccgg cactgcgacc     1080

actttaacag acctgaccaa tcccactatc actgtagtga catccgtgac ctctaacatg     1140

gacagccacg aatccggaag cccctcacaa actaccttaa caaacctttt ctaacattgg     1200

tttttttttt ttagttttta aattcttcct cttcttttta ttattattct aattattatt     1260

attttattat ttacaagact ttttttttct tctaacccac aagatatttg gggaataaaa     1320

ataacagctt ggtgtgtagc atctgcagcc acttggcaaa tgagtttaca gtattgtctc     1380

ctttaagtga atatattttg tctacaaagt gtatttggat ttaaaaaaat taattaggtc     1440

tttcagttgg taaggagagt ttttgaataa ttctaataag tgcctcttaa aattgtatgt     1500

tacttatttc cagaatctcg aagaaaaaag aaaaaagagt ggtattatta tgggcaaata     1560

atcatattcc cacttaaatg attaggttaa taaagaacca gataattaat tagttacttt     1620

ttaaatcttg caattgtatg tgtgattatg gagttttgaa aacgttacat tttttaaatc     1680

ttaaaactga aaacttgttt ttagtatttc tatttcttac ctgaactgtt aattcaagtg     1740

aggaatatga tgaaataaaa gcattaacta cagacatttt aaatagtaat gattaattag     1800

gtgagaaatc tattacagga atgtgacttt tccttctctt aggggtgtac aactctaaaa     1860

actttttact tggttatttg tttttcaaca tttgaaaaat acttaagctc cctatgtatc     1920

catgaaaatt ccgcattgat tttgacattc catactttta acctcctaaa gctaaaaaca     1980

atagctcgga aaccattctt tctagttact ttttttccca gggaaaatgg aaataagcaa     2040

aatataatgt tttaagaagt aaaaaaatca atataatt                             2078


<210>  1114
<211>  3419
<212>  DNA
<213>  homo sapiens

<400>  1114
ccggcctcag ggacgcaccg gagccgcctt tccgggcctc aggcggattc tccggcgcgg       60

cccgccccgc ccctcggact ccccgggccg cccccggccc ccattcgggc cgggcctcgc      120

tgcggcggcg actgagccag gctgggccgc gtccctgagt cccagagtcg gcgcggcgcg      180

gcaggggcag ccttccacca cggggagccc agctgtcagc cgcctcacag gaagatgctg      240

cgtcggcggg gcagccctgg catgggtgtg catgtgggtg cagccctggg agcactgtgg      300

ttctgcctca caggagccct ggaggtccag gtccctgaag acccagtggt ggcactggtg      360

ggcaccgatg ccaccctgtg ctgctccttc tcccctgagc ctggcttcag cctggcacag      420

ctcaacctca tctggcagct gacagatacc aaacagctgg tgcacagctt tgctgagggc      480

caggaccagg gcagcgccta tgccaaccgc acggccctct tcccggacct gctggcacag      540

ggcaacgcat ccctgaggct gcagcgcgtg cgtgtggcgg acgagggcag cttcacctgc      600

ttcgtgagca tccgggattt cggcagcgct gccgtcagcc tgcaggtggc cgctccctac      660

tcgaagccca gcatgaccct ggagcccaac aaggacctgc ggccagggga cacggtgacc      720

atcacgtgct ccagctacca gggctaccct gaggctgagg tgttctggca ggatgggcag      780

ggtgtgcccc tgactggcaa cgtgaccacg tcgcagatgg ccaacgagca gggcttgttt      840

gatgtgcaca gcatcctgcg ggtggtgctg ggtgcaaatg gcacctacag ctgcctggtg      900

cgcaaccccg tgctgcagca ggatgcgcac agctctgtca ccatcacacc ccagagaagc      960

cccacaggag ccgtggaggt ccaggtccct gaggacccgg tggtggccct agtgggcacc     1020

gatgccaccc tgcgctgctc cttctccccc gagcctggct tcagcctggc acagctcaac     1080

ctcatctggc agctgacaga caccaaacag ctggtgcaca gtttcaccga aggccgggac     1140

cagggcagcg cctatgccaa ccgcacggcc ctcttcccgg acctgctggc acaaggcaat     1200

gcatccctga ggctgcagcg cgtgcgtgtg gcggacgagg gcagcttcac ctgcttcgtg     1260

agcatccggg atttcggcag cgctgccgtc agcctgcagg tggccgctcc ctactcgaag     1320

cccagcatga ccctggagcc caacaaggac ctgcggccag gggacacggt gaccatcacg     1380

tgctccagct accggggcta ccctgaggct gaggtgttct ggcaggatgg gcagggtgtg     1440

cccctgactg gcaacgtgac cacgtcgcag atggccaacg agcagggctt gtttgatgtg     1500

cacagcgtcc tgcgggtggt gctgggtgcg aatggcacct acagctgcct ggtgcgcaac     1560

cccgtgctgc agcaggatgc gcacggctct gtcaccatca cagggcagcc tatgacattc     1620

cccccagagg ccctgtgggt gaccgtgggg ctgtctgtct gtctcattgc actgctggtg     1680

gccctggctt tcgtgtgctg gagaaagatc aaacagagct gtgaggagga gaatgcagga     1740

gctgaggacc aggatgggga gggagaaggc tccaagacag ccctgcagcc tctgaaacac     1800

tctgacagca aagaagatga tggacaagaa atagcctgac catgaggacc agggagctgc     1860

tacccctccc tacagctcct accctctggc tgcaatgggg ctgcactgtg agccctgccc     1920

ccaacagatg catcctgctc tgacaggtgg gctccttctc caaaggatgc gatacacaga     1980

ccactgtgca gccttatttc tccaatggac atgattccca agtcatcctg ctgccttttt     2040

tcttatagac acaatgaaca gaccacccac aaccttagtt ctctaagtca tcctgcctgc     2100

tgccttattt cacagtacat acatttctta gggacacagt acactgacca catcaccacc     2160

ctcttcttcc agtgctgcgt ggaccatctg gctgcctttt ttctccaaaa gatgcaatat     2220

tcagactgac tgaccccctg ccttatttca ccaaagacac gatgcatagt caccccggcc     2280

ttgtttctcc aatggccgtg atacactagt gatcatgttc agccctgctt ccacctgcat     2340

agaatctttt cttctcagac agggacagtg cggcctcaac atctcctgga gtctagaagc     2400

tgtttccttt cccctccttc ctcctcttgc tctagcctta atactggcct tttccctccc     2460

tgccccaagt gaagacaggg cactctgcgc ccaccacatg cacagctgtg catggagacc     2520

tgcaggtgca cgtgctggaa cacgtgtggt tcccccctgg cccagcctcc tctgcagtgc     2580

ccctctcccc tgcccatcct ccccacggaa gcatgtgctg gtcacactgg ttctccaggg     2640

gtctgtgatg gggcccctgg gggtcagctt ctgtccctct gccttctcac ctctttgttc     2700

ctttcttttc atgtatccat tcagttgatg tttattgagc aactacagat gtcagcactg     2760

tgttaggtgc tgggggccct gcgtgggaag ataaagttcc tccctcaagg actccccatc     2820

cagctgggag acagacaact aactacactg caccctgcgg tttgcagggg gctcctgcct     2880

ggctccctgc tccacacctc ctctgtggct caaggcttcc tggatacctc acccccatcc     2940

cacccataat tcttacccag agcatggggt tggggcggaa acctggagag agggacatag     3000

cccctcgcca cggctagaga atctggtggt gtccaaaatg tctgtccagg tgtgggcagg     3060

tgggcaggca ccaaggccct ctggaccttt catagcagca gaaaaggcag agcctggggc     3120

agggcagggc caggaatgct ttggggacac cgaggggact gccccccacc cccaccatgg     3180

tgctattctg gggctggggc agtcttttcc tggcttgcct ctggccagct cctggcctct     3240

ggtagagtga gacttcagac gttctgatgc cttccggatg tcatctctcc ctgccccagg     3300

aatggaagat gtgaggactt ctaatttaaa tgtgggactc ggagggattt tgtaaactgg     3360

gggtatattt tggggaaaat aaatgtcttt gtaaaaagct taaaaaaaaa aaaaaaaaa      3419


<210>  1115
<211>  2765
<212>  DNA
<213>  homo sapiens

<400>  1115
ccggcctcag ggacgcaccg gagccgcctt tccgggcctc aggcggattc tccggcgcgg       60

cccgccccgc ccctcggact ccccgggccg cccccggccc ccattcgggc cgggcctcgc      120

tgcggcggcg actgagccag gctgggccgc gtccctgagt cccagagtcg gcgcggcgcg      180

gcaggggcag ccttccacca cggggagccc agctgtcagc cgcctcacag gaagatgctg      240

cgtcggcggg gcagccctgg catgggtgtg catgtgggtg cagccctggg agcactgtgg      300

ttctgcctca caggagccct ggaggtccag gtccctgaag acccagtggt ggcactggtg      360

ggcaccgatg ccaccctgtg ctgctccttc tcccctgagc ctggcttcag cctggcacag      420

ctcaacctca tctggcagct gacagatacc aaacagctgg tgcacagctt tgctgagggc      480

caggaccagg gcagcgccta tgccaaccgc acggccctct tcccggacct gctggcacag      540

ggcaacgcat ccctgaggct gcagcgcgtg cgtgtggcgg acgagggcag cttcacctgc      600

ttcgtgagca tccgggattt cggcagcgct gccgtcagcc tgcaggtggc cgctccctac      660

tcgaagccca gcatgaccct ggagcccaac aaggacctgc ggccagggga cacggtgacc      720

atcacgtgct ccagctaccg gggctaccct gaggctgagg tgttctggca ggatgggcag      780

ggtgtgcccc tgactggcaa cgtgaccacg tcgcagatgg ccaacgagca gggcttgttt      840

gatgtgcaca gcgtcctgcg ggtggtgctg ggtgcgaatg gcacctacag ctgcctggtg      900

cgcaaccccg tgctgcagca ggatgcgcac ggctctgtca ccatcacagg gcagcctatg      960

acattccccc cagaggccct gtgggtgacc gtggggctgt ctgtctgtct cattgcactg     1020

ctggtggccc tggctttcgt gtgctggaga aagatcaaac agagctgtga ggaggagaat     1080

gcaggagctg aggaccagga tggggaggga gaaggctcca agacagccct gcagcctctg     1140

aaacactctg acagcaaaga agatgatgga caagaaatag cctgaccatg aggaccaggg     1200

agctgctacc cctccctaca gctcctaccc tctggctgca atggggctgc actgtgagcc     1260

ctgcccccaa cagatgcatc ctgctctgac aggtgggctc cttctccaaa ggatgcgata     1320

cacagaccac tgtgcagcct tatttctcca atggacatga ttcccaagtc atcctgctgc     1380

cttttttctt atagacacaa tgaacagacc acccacaacc ttagttctct aagtcatcct     1440

gcctgctgcc ttatttcaca gtacatacat ttcttaggga cacagtacac tgaccacatc     1500

accaccctct tcttccagtg ctgcgtggac catctggctg ccttttttct ccaaaagatg     1560

caatattcag actgactgac cccctgcctt atttcaccaa agacacgatg catagtcacc     1620

ccggccttgt ttctccaatg gccgtgatac actagtgatc atgttcagcc ctgcttccac     1680

ctgcatagaa tcttttcttc tcagacaggg acagtgcggc ctcaacatct cctggagtct     1740

agaagctgtt tcctttcccc tccttcctcc tcttgctcta gccttaatac tggccttttc     1800

cctccctgcc ccaagtgaag acagggcact ctgcgcccac cacatgcaca gctgtgcatg     1860

gagacctgca ggtgcacgtg ctggaacacg tgtggttccc ccctggccca gcctcctctg     1920

cagtgcccct ctcccctgcc catcctcccc acggaagcat gtgctggtca cactggttct     1980

ccaggggtct gtgatggggc ccctgggggt cagcttctgt ccctctgcct tctcacctct     2040

ttgttccttt cttttcatgt atccattcag ttgatgttta ttgagcaact acagatgtca     2100

gcactgtgtt aggtgctggg ggccctgcgt gggaagataa agttcctccc tcaaggactc     2160

cccatccagc tgggagacag acaactaact acactgcacc ctgcggtttg cagggggctc     2220

ctgcctggct ccctgctcca cacctcctct gtggctcaag gcttcctgga tacctcaccc     2280

ccatcccacc cataattctt acccagagca tggggttggg gcggaaacct ggagagaggg     2340

acatagcccc tcgccacggc tagagaatct ggtggtgtcc aaaatgtctg tccaggtgtg     2400

ggcaggtggg caggcaccaa ggccctctgg acctttcata gcagcagaaa aggcagagcc     2460

tggggcaggg cagggccagg aatgctttgg ggacaccgag gggactgccc cccaccccca     2520

ccatggtgct attctggggc tggggcagtc ttttcctggc ttgcctctgg ccagctcctg     2580

gcctctggta gagtgagact tcagacgttc tgatgccttc cggatgtcat ctctccctgc     2640

cccaggaatg gaagatgtga ggacttctaa tttaaatgtg ggactcggag ggattttgta     2700

aactgggggt atattttggg gaaaataaat gtctttgtaa aaagcttaaa aaaaaaaaaa     2760

aaaaa                                                                 2765


<210>  1116
<211>  1715
<212>  DNA
<213>  homo sapiens

<400>  1116
ggcctgccga gtccgcggcg ttccccggct gcagccggga gggggccgag gagtgactga       60

gccccgggct gtgcagtccg acgccgactg aggcacgagc gggtgacgct gggcctgcag      120

cgcggagcag aaagcagaac ccgcagagtc ctccctgctg ctgtgtggac gacacgtggg      180

cacaggcaga agtgggccct gtgaccagct gcactggttt cgtggaagga agctccagga      240

ctggcgggat gggctcagcc tgtatcaaag tcaccaaata ctttctcttc ctcttcaact      300

tgatcttctt tatcctgggc gcagtgatcc tgggcttcgg ggtgtggatc ctggccgaca      360

agagcagttt catctctgtc ctgcaaacct cctccagctc gcttaggatg ggggcctatg      420

tcttcatcgg cgtgggggca gtcactatgc tcatgggctt cctgggctgc atcggcgccg      480

tcaacgaggt ccgctgcctg ctggggctgt actttgcttt cctgctcctg atcctcattg      540

cccaggtgac ggccggggcc ctcttctact tcaacatggg caagctgaag caggagatgg      600

gcggcatcgt gactgagctc attcgagact acaacagcag tcgcgaggac agcctgcagg      660

atgcctggga ctacgtgcag gctcaggtga agtgctgcgg ctgggtcagc ttctacaact      720

ggacagacaa cgctgagctc atgaatcgcc ctgaggtcac ctacccctgt tcctgcgaag      780

tcaaggggga agaggacaac agcctttctg tgaggaaggg cttctgcgag gcccccggca      840

acaggaccca gagtggcaac caccctgagg actggcctgt gtaccaggag ggctgcatgg      900

agaaggtgca ggcgtggctg caggagaacc tgggcatcat cctcggcgtg ggcgtgggtg      960

tggccatcat cgagctcctg gggatggtcc tgtccatctg cttgtgccgg cacgtccatt     1020

ccgaagacta cagcaaggtc cccaagtact gaggcagctg ctatccccat ctccctgcct     1080

ggcccccaac ctcagggctc ccaggggtct ccctggctcc ctcctccagg cctgcctccc     1140

acttcactgc gaagaccctc ttgcccatcc tgactgaaag tagggggctt tctggggcct     1200

agcgatctct cctggcctat ccgctgccag ccttgagccc tggctgttct gtggttcctc     1260

tgctcaccgc ccatcagggt tctcttagca actcagagaa aaatgctccc cacagcgtcc     1320

ctggcgcagg tgggctggac ttctacctgc cctcaagggt gtgtatattg tataggggca     1380

actgtatgaa aaattgggga ggagggggcc gggcgcggtg gctcacgcct gtaatcccag     1440

cactttggga ggccgaggcg ggtggatcac gaggtcagga gatcgagacc atcctggcta     1500

acatggtgaa accccgtctc tactaaaaat acaaaaaaaa tttagccggg cgcggtggcg     1560

ggcacctgta gtcccagcta cttgggaggc tgaggcagga gaatggtgtg aacccgggag     1620

cggaggttgc agtgagctga gatcgtgcta ctgcactcca gcctggggga cagaaagaga     1680

ctccgtctca aaaaaaaaaa aaaaaaaaaa aaaaa                                1715


<210>  1117
<211>  2099
<212>  DNA
<213>  homo sapiens

<400>  1117
agaaagtagc agaaagtgag gctggcaggc ggcggcaaag gagccggcgc gcggcggcgg       60

caggaagtct gtgcccgaga acagcagaaa taagagccag ggagggaccg cggccgcggc      120

ggcggcggcg agagcgaaag aggaaactgc agaggaggaa gctgcgccgc agcccgagcc      180

gcccggcatc cccgccgcct ctgcgcccgc gccgcgcccc cggcgccccc tccccagcgc      240

gcccccggcc gctcctccgc gccgcgctcg tcggccatgg cccgggagaa cggcgagagc      300

agctcctcct ggaaaaagca agctgaagac atcaagaaga tcttcgagtt caaagagacc      360

ctcggaaccg gggccttttc cgaagtggtt ttagctgaag agaaggcaac tggcaagctc      420

tttgctgtga agtgtatccc taagaaggcg ctgaagggca aggaaagcag catagagaat      480

gagatagccg tcctgagaaa gattaagcat gaaaatattg ttgccctgga agacatttat      540

gaaagcccaa atcacctgta cttggtcatg cagctggtgt ccggtggaga gctgtttgac      600

cggatagtgg agaaggggtt ttatacagag aaggatgcca gcactctgat ccgccaagtc      660

ttggacgccg tgtactatct ccacagaatg ggcatcgtcc acagagacct caagcccgaa      720

aatctcttgt actacagtca agatgaggag tccaaaataa tgatcagtga ctttggattg      780

tcaaaaatgg agggcaaagg agatgtgatg tccactgcct gtggaactcc aggctatgtc      840

gctcctgaag tcctcgccca gaaaccttac agcaaagccg ttgactgctg gtccatcgga      900

gtgattgcct acatcttgct ctgcggctac cctccttttt atgatgaaaa tgactccaag      960

ctctttgagc agatcctcaa ggcggaatat gagtttgact ctccctactg ggatgacatc     1020

tccgactctg caaaagactt cattcggaac ctgatggaga aggacccgaa taaaagatac     1080

acgtgtgagc aggcagctcg gcacccatgg atcgctggtg acacagccct caacaaaaac     1140

atccacgagt ccgtcagcgc ccagatccgg aaaaactttg ccaagagcaa atggagacaa     1200

gcatttaatg ccacggccgt cgtcagacat atgagaaaac tacacctcgg cagcagcctg     1260

gacagttcaa atgcaagtgt ttcgagcagc ctcagtttgg ccagccaaaa agactgtgcg     1320

tatgtagcaa aaccagaatc cctcagctga cactgaagac gagcctgggg tggagaggag     1380

ggagccggca tctgccgagc acctcctgtt tgccaggcgc tttctatact taatcccatg     1440

tcatgcgacc ctaggacttt ttttaacatg taatcactgg gctgggtgca gtggctcacg     1500

cctgtaatcc caacactttg ggaggctgag gcaggaggac tgtttgagtt caggagtttt     1560

aagaccagcc tgaccaacat ggtgaaaccc catctctact aaaatataaa aattagccgg     1620

gtgtggtggc gagcacctgt aatgtcagct acttgggagg ctgaggcagg agaatcactt     1680

gaacccagga agcggaggtt gcaatgagct gagatcacac cactgcactc cagcctgggt     1740

gacagattga gactccctct caaaaaaaaa aaagaaaaat cattgaacac tcgtggaacc     1800

ctaggtattg ctatttccat ttacagttga ggaatccagg gctcaagtcc tcgcagccat     1860

gtctgtctgg ataaaggcct ggactctttc tcatctccat ccttccctct gatttacctc     1920

tcattgtaca gtcactcttg cggattgagg aagggagagc agagcctcag gacagcctcc     1980

tgccattgac ttccataatg tatatatttt ggatgcagac aatgataatt tgagctcatt     2040

tatgtgaagt gcattgactt tgcaataaaa gtaatagtat ttcattgtca aaaaaaaaa      2099


<210>  1118
<211>  4903
<212>  DNA
<213>  homo sapiens

<400>  1118
gtcgtttgcg gcggcgcagg cgcggtgcgg gcggcggacg ggcgggcgct tcgccgtttg       60

aatggctgcg ggcccgggcc ctcacctcac ctgaggtccg gccgcccagg ggtgcgctat      120

gccgtcggga ggtgaccagt cgccaccgcc cccgcctccc cctccggcgg cggcagcctc      180

ggatgaggag gaggaggacg acggcgaggc ggaagacgcc gcgccgcctg ccgagtcgcc      240

cacccctcag atccagcagc ggttcgacga gctgtgcagc cgcctcaaca tggacgaggc      300

ggcgcgggcc gaggcctggg acagctaccg cagcatgagc gaaagctaca cgctggaggg      360

aaatgatctt cattggttag catgtgcctt atatgtggct tgcagaaaat ctgttccaac      420

tgtaagcaaa gggacagtgg aaggaaacta tgtatcttta actagaatcc tgaaatgttc      480

agagcagagc ttaatcgaat tttttaataa gatgaagaag tgggaagaca tggcaaatct      540

acccccacat ttcagagaac gtactgagag attagaaaga aacttcactg tttctgctgt      600

aatttttaag aaatatgaac ccatttttca ggacatcttt aaataccctc aagaggagca      660

acctcgtcag cagcgaggaa ggaaacagcg gcgacagccc tgtactgtgt ctgaaatttt      720

ccatttttgt tgggtgcttt ttatatatgc aaaaggtaat ttccccatga ttagtgatga      780

tttggtcaat tcttatcacc tgctgctgtg tgctttggac ttagtttatg gaaatgcact      840

tcagtgttct aatcgtaaag aacttgtgaa ccctaatttt aaaggcttat ctgaagattt      900

tcatgctaaa gattctaaac cttcctctga ccccccttgt atcattgaga aactgtgttc      960

cttacatgat ggcctagttt tggaagcaaa ggggataaag gaacatttct ggaaacccta     1020

tattaggaaa ctttatgaaa aaaagctcct taagggaaaa gaagaaaatc tcactgggtt     1080

tctagaacct gggaactttg gagagagttt taaagccatc aataaggcct atgaggagta     1140

tgttttatct gttgggaatt tagatgagcg gatatttctt ggagaggatg ctgaggagga     1200

aattgggact ctctcaaggt gtctgaacgc tggttcagga acagagactg ctgaaagggt     1260

gcagatgaaa aacatcttac agcagcattt tgacaagtcc aaagcactta gaatctccac     1320

accactaact ggtgttaggt acattaagga gaatagccct tgtgtgactc cagtttctac     1380

agctacgcat agcttgagtc gtcttcacac catgctgaca ggcctcagga atgcaccaag     1440

tgagaaactg gaacagattc tcaggacatg ttccagagat ccaacccagg ctattgctaa     1500

cagactgaaa gaaatgtttg aaatatattc tcagcatttc cagccagacg aggatttcag     1560

taattgtgct aaagaaattg ccagcaaaca ttttcgtttt gcggagatgc tttactataa     1620

agtattagaa tctgttattg agcaggaaca aaaaagacta ggagacatgg atttatctgg     1680

tattctggaa caagatgcgt tccacagatc tctcttggcc tgctgccttg aggtcgtcac     1740

tttttcttat aagcctcctg ggaattttcc atttattact gaaatatttg atgtgcctct     1800

ttatcatttt tataaggtga tagaagtatt cattagagca gaagatggcc tttgtagaga     1860

ggtggtaaaa caccttaatc agattgaaga acagatctta gatcatttgg catggaaacc     1920

agagtctcca ctctgggaaa aaattagaga caatgaaaac agagttccta catgtgaaga     1980

ggtcatgcca cctcagaacc tggaaagggc agatgaaatt tgcattgctg gctccccttt     2040

gactcccaga agggtgactg aagttcgtgc tgatactgga ggacttggaa ggagcataac     2100

atctccaacc acattatacg ataggtacag ctccccacca gccagcacta ccagaaggcg     2160

gctatttgtt gagaatgata gcccctctga tggagggacg cctgggcgca tgcccccaca     2220

gcccctagtc aatgctgtcc ctgtgcagaa tgtatctggg gagactgttt ctgtcacacc     2280

agttcctgga cagactttgg tcaccatggc aaccgccact gtcacagcca acaatgggca     2340

aacggtaacc attcctgtgc aaggtattgc caatgaaaat ggagggataa cattcttccc     2400

tgtccaagtc aatgttgggg ggcaggcaca agctgtgaca ggctccatcc agcccctcag     2460

tgctcaggcc ctggctggaa gtctgagctc tcaacaggtg acaggaacaa ctttgcaagt     2520

ccctggtcaa gtggccattc aacagatttc cccaggtggc caacagcaga agcaaggcca     2580

gtctgtaacc agcagtagta atagacccag gaagaccagc tctttatcgc ttttctttag     2640

aaaggtatac catttagcag ctgtccgcct tcgggatctc tgtgccaaac tagatatttc     2700

agatgaattg aggaaaaaaa tctggacctg ctttgaattc tccataattc agtgtcctga     2760

acttatgatg gacagacatc tggaccagtt attaatgtgt gccatttatg tgatggcaaa     2820

ggtcacaaaa gaagataagt ccttccagaa cattatgcgt tgttatagga ctcagccgca     2880

ggcccggagc caggtgtata gaagtgtttt gataaaaggg aaaagaaaaa gaagaaattc     2940

tggcagcagt gatagcagaa gccatcagaa ttctccaaca gaactaaaca aagatagaac     3000

cagtagagac tccagtccag ttatgaggtc aagcagcacc ttgccagttc cacagcccag     3060

cagtgctcct cccacaccta ctcgcctcac aggtgccaac agtgacatgg aagaagagga     3120

gaggggagac ctcattcagt tctacaacaa catctacatc aaacagatta agacatttgc     3180

catgaagtac tcacaggcaa atatggatgc tcctccactc tctccctatc catttgtaag     3240

aacaggctcc cctcgccgaa tacagttgtc tcaaaatcat cctgtctaca tttccccaca     3300

taaaaatgaa acaatgcttt ctcctcgaga aaagattttc tattacttca gcaacagtcc     3360

ttcaaagaga ctgagagaaa ttaatagtat gatacgcaca ggagaaactc ctactaaaaa     3420

gagaggaatt cttttggaag atggaagtga atcacctgca aaaagaattt gcccagaaaa     3480

tcattctgcc ttattacgcc gtctccaaga tgtagctaat gaccgtggtt cccactgagg     3540

ttagtctctt gtattaaact cttcacaaaa tctgtttagc agcagccttt aatgcatcta     3600

gattatggag cttttttcct taatccagct gatgagttac agcctgttag taacatgagg     3660

ggacattttg gtgagaaatg ggacttaact ccttccagtg tccttagaac attttaattc     3720

atcccaactg tctttttttc cctaccattc agtgattact gtcaaggctg cttagaatcc     3780

aaacttggat ttttgactct ggcaaagctt ttagaaatac tgcaagaaaa tgatgtgtac     3840

ccaaacgtga gcataggagg cttctgttga cgtactccaa cagaagaact gtgtttcaag     3900

ttcaatccta cctgttttgt ggtcagctgt agtcctcata aaaagcaaaa caaaaattag     3960

gtattttgtc ctaaaacacc tggtaggagt gtgtgatttt ttgcattcct gacaaaggag     4020

agcacaccca ggtttggagg tcctaggtca ttagccctcg tctcccgttc cctttgtgca     4080

catcttccct ctccccattc ggtgtggtgc agtgtgaaaa gtccttgatt gttcgggtgt     4140

gcaatgtctg agtgaacctg tataagtgga ggcactttag ggctgtaaaa tgcatgattt     4200

tgtaacccag attttgctgt atatttgtga tagcactttc tacaatgtga actttattaa     4260

atacaaaact tccaggctaa acatccaata ttttctttaa tgcttttata tttttttaaa     4320

atgttaaaac ccctatagcc accttttggg aatgttttaa attctccagt tttttgttat     4380

atagggatca accagctaag aaaagatttt aatcaagttg aattgagggg attaatatga     4440

aaacttatga cctcttcctt taggagggag ttatctaaaa gaaatgtcta ttaaggtgat     4500

atatttaaaa atatttttgg gtgttcctgg cagtttaaaa aaattggttg gagaatttag     4560

gtttttatta gtaccatagt accatttata caaattagaa aatgttattt aacagctgaa     4620

ttatctatac atatctttat taatcactat tgttccagca gttttcaagt caaattaata     4680

atcttattag ggagaaaatt caattgtaaa ttgaatcagt ataaacaaag ttactaggta     4740

acttcatatt gctgagagaa atatggaact tacattgttc aattagaata gtgttctgca     4800

aaaatattta taaaacttct caagatactg ctactgtaat tttatatgaa gataagtgta     4860

tttttcaata aagcatttat aaattaaaaa aaaaaaaaaa aaa                       4903


<210>  1119
<211>  2723
<212>  DNA
<213>  homo sapiens

<400>  1119
ggcggcgctt gattgggctg ggggggccaa ataaaagcga tggcgattgg gctgccgcgt       60

ttggcgctcg gtccggtcgc gtccgacacc cggtgggact cagaaggcag tggagccccg      120

gcggcggcgg cggcggcgcg cgggggcgac gcgcgggaac aacgcgagtc ggcgcgcggg      180

acgaagaata atcatgggcc agactgggaa gaaatctgag aagggaccag tttgttggcg      240

gaagcgtgta aaatcagagt acatgcgact gagacagctc aagaggttca gacgagctga      300

tgaagtaaag agtatgttta gttccaatcg tcagaaaatt ttggaaagaa cggaaatctt      360

aaaccaagaa tggaaacagc gaaggataca gcctgtgcac atcctgactt ctgtgagctc      420

attgcgcggg actagggagt gttcggtgac cagtgacttg gattttccaa cacaagtcat      480

cccattaaag actctgaatg cagttgcttc agtacccata atgtattctt ggtctcccct      540

acagcagaat tttatggtgg aagatgaaac tgttttacat aacattcctt atatgggaga      600

tgaagtttta gatcaggatg gtactttcat tgaagaacta ataaaaaatt atgatgggaa      660

agtacacggg gatagagaat gtgggtttat aaatgatgaa atttttgtgg agttggtgaa      720

tgcccttggt caatataatg atgatgacga tgatgatgat ggagacgatc ctgaagaaag      780

agaagaaaag cagaaagatc tggaggatca ccgagatgat aaagaaagcc gcccacctcg      840

gaaatttcct tctgataaaa tttttgaagc catttcctca atgtttccag ataagggcac      900

agcagaagaa ctaaaggaaa aatataaaga actcaccgaa cagcagctcc caggcgcact      960

tcctcctgaa tgtaccccca acatagatgg accaaatgct aaatctgttc agagagagca     1020

aagcttacac tcctttcata cgcttttctg taggcgatgt tttaaatatg actgcttcct     1080

acatcgtaag tgcaattatt cttttcatgc aacacccaac acttataagc ggaagaacac     1140

agaaacagct ctagacaaca aaccttgtgg accacagtgt taccagcatt tggagggagc     1200

aaaggagttt gctgctgctc tcaccgctga gcggataaag accccaccaa aacgtccagg     1260

aggccgcaga agaggacggc ttcccaataa cagtagcagg cccagcaccc ccaccattaa     1320

tgtgctggaa tcaaaggata cagacagtga tagggaagca gggactgaaa cggggggaga     1380

gaacaatgat aaagaagaag aagagaagaa agatgaaact tcgagctcct ctgaagcaaa     1440

ttctcggtgt caaacaccaa taaagatgaa gccaaatatt gaacctcctg agaatgtgga     1500

gtggagtggt gctgaagcct caatgtttag agtcctcatt ggcacttact atgacaattt     1560

ctgtgccatt gctaggttaa ttgggaccaa aacatgtaga caggtgtatg agtttagagt     1620

caaagaatct agcatcatag ctccagctcc cgctgaggat gtggatactc ctccaaggaa     1680

aaagaagagg aaacaccggt tgtgggctgc acactgcaga aagatacagc tgaaaaagga     1740

cggctcctct aaccatgttt acaactatca accctgtgat catccacggc agccttgtga     1800

cagttcgtgc ccttgtgtga tagcacaaaa tttttgtgaa aagttttgtc aatgtagttc     1860

agagtgtcaa aaccgctttc cgggatgccg ctgcaaagca cagtgcaaca ccaagcagtg     1920

cccgtgctac ctggctgtcc gagagtgtga ccctgacctc tgtcttactt gtggagccgc     1980

tgaccattgg gacagtaaaa atgtgtcctg caagaactgc agtattcagc ggggctccaa     2040

aaagcatcta ttgctggcac catctgacgt ggcaggctgg gggattttta tcaaagatcc     2100

tgtgcagaaa aatgaattca tctcagaata ctgtggagag attatttctc aagatgaagc     2160

tgacagaaga gggaaagtgt atgataaata catgtgcagc tttctgttca acttgaacaa     2220

tgattttgtg gtggatgcaa cccgcaaggg taacaaaatt cgttttgcaa atcattcggt     2280

aaatccaaac tgctatgcaa aagttatgat ggttaacggt gatcacagga taggtatttt     2340

tgccaagaga gccatccaga ctggcgaaga gctgtttttt gattacagat acagccaggc     2400

tgatgccctg aagtatgtcg gcatcgaaag agaaatggaa atcccttgac atctgctacc     2460

tcctcccccc tcctctgaaa cagctgcctt agcttcagga acctcgagta ctgtgggcaa     2520

tttagaaaaa gaacatgcag tttgaaattc tgaatttgca aagtactgta agaataattt     2580

atagtaatga gtttaaaaat caacttttta ttgccttctc accagctgca aagtgttttg     2640

taccagtgaa tttttgcaat aatgcagtat ggtacatttt tcaactttga ataaagaata     2700

cttgaacttg tccttgttga atc                                             2723


<210>  1120
<211>  2591
<212>  DNA
<213>  homo sapiens

<400>  1120
ggcggcgctt gattgggctg ggggggccaa ataaaagcga tggcgattgg gctgccgcgt       60

ttggcgctcg gtccggtcgc gtccgacacc cggtgggact cagaaggcag tggagccccg      120

gcggcggcgg cggcggcgcg cgggggcgac gcgcgggaac aacgcgagtc ggcgcgcggg      180

acgaagaata atcatgggcc agactgggaa gaaatctgag aagggaccag tttgttggcg      240

gaagcgtgta aaatcagagt acatgcgact gagacagctc aagaggttca gacgagctga      300

tgaagtaaag agtatgttta gttccaatcg tcagaaaatt ttggaaagaa cggaaatctt      360

aaaccaagaa tggaaacagc gaaggataca gcctgtgcac atcctgactt ctgtgagctc      420

attgcgcggg actagggagg tggaagatga aactgtttta cataacattc cttatatggg      480

agatgaagtt ttagatcagg atggtacttt cattgaagaa ctaataaaaa attatgatgg      540

gaaagtacac ggggatagag aatgtgggtt tataaatgat gaaatttttg tggagttggt      600

gaatgccctt ggtcaatata atgatgatga cgatgatgat gatggagacg atcctgaaga      660

aagagaagaa aagcagaaag atctggagga tcaccgagat gataaagaaa gccgcccacc      720

tcggaaattt ccttctgata aaatttttga agccatttcc tcaatgtttc cagataaggg      780

cacagcagaa gaactaaagg aaaaatataa agaactcacc gaacagcagc tcccaggcgc      840

acttcctcct gaatgtaccc ccaacataga tggaccaaat gctaaatctg ttcagagaga      900

gcaaagctta cactcctttc atacgctttt ctgtaggcga tgttttaaat atgactgctt      960

cctacatcct tttcatgcaa cacccaacac ttataagcgg aagaacacag aaacagctct     1020

agacaacaaa ccttgtggac cacagtgtta ccagcatttg gagggagcaa aggagtttgc     1080

tgctgctctc accgctgagc ggataaagac cccaccaaaa cgtccaggag gccgcagaag     1140

aggacggctt cccaataaca gtagcaggcc cagcaccccc accattaatg tgctggaatc     1200

aaaggataca gacagtgata gggaagcagg gactgaaacg gggggagaga acaatgataa     1260

agaagaagaa gagaagaaag atgaaacttc gagctcctct gaagcaaatt ctcggtgtca     1320

aacaccaata aagatgaagc caaatattga acctcctgag aatgtggagt ggagtggtgc     1380

tgaagcctca atgtttagag tcctcattgg cacttactat gacaatttct gtgccattgc     1440

taggttaatt gggaccaaaa catgtagaca ggtgtatgag tttagagtca aagaatctag     1500

catcatagct ccagctcccg ctgaggatgt ggatactcct ccaaggaaaa agaagaggaa     1560

acaccggttg tgggctgcac actgcagaaa gatacagctg aaaaaggacg gctcctctaa     1620

ccatgtttac aactatcaac cctgtgatca tccacggcag ccttgtgaca gttcgtgccc     1680

ttgtgtgata gcacaaaatt tttgtgaaaa gttttgtcaa tgtagttcag agtgtcaaaa     1740

ccgctttccg ggatgccgct gcaaagcaca gtgcaacacc aagcagtgcc cgtgctacct     1800

ggctgtccga gagtgtgacc ctgacctctg tcttacttgt ggagccgctg accattggga     1860

cagtaaaaat gtgtcctgca agaactgcag tattcagcgg ggctccaaaa agcatctatt     1920

gctggcacca tctgacgtgg caggctgggg gatttttatc aaagatcctg tgcagaaaaa     1980

tgaattcatc tcagaatact gtggagagat tatttctcaa gatgaagctg acagaagagg     2040

gaaagtgtat gataaataca tgtgcagctt tctgttcaac ttgaacaatg attttgtggt     2100

ggatgcaacc cgcaagggta acaaaattcg ttttgcaaat cattcggtaa atccaaactg     2160

ctatgcaaaa gttatgatgg ttaacggtga tcacaggata ggtatttttg ccaagagagc     2220

catccagact ggcgaagagc tgttttttga ttacagatac agccaggctg atgccctgaa     2280

gtatgtcggc atcgaaagag aaatggaaat cccttgacat ctgctacctc ctcccccctc     2340

ctctgaaaca gctgccttag cttcaggaac ctcgagtact gtgggcaatt tagaaaaaga     2400

acatgcagtt tgaaattctg aatttgcaaa gtactgtaag aataatttat agtaatgagt     2460

ttaaaaatca actttttatt gccttctcac cagctgcaaa gtgttttgta ccagtgaatt     2520

tttgcaataa tgcagtatgg tacatttttc aactttgaat aaagaatact tgaacttgtc     2580

cttgttgaat c                                                          2591


<210>  1121
<211>  4154
<212>  DNA
<213>  homo sapiens

<400>  1121
gttggaggtg gagtagttca gaatcaactg acgcagccgg gaattgagct ttgcaaagcc       60

acttgcaagg aagggaagca tctgcccaac cctcccccac cgcgcgccct ggatcctctg      120

cctgccccct cccccgtgac gtcaccctag tcctgtcccg gggagcctgc aaagcctctc      180

agattcaaac tgctagacgc actgctgcca ccgccaccga attggaaacg cgcgcccagg      240

ctccgtcgtc gccttcgccc gccgaccggg ccagccggct ctccgacctc cctacagaat      300

cgcaccccag tccctccctg gcagctcggc ttccctcagc tccaactctt ctcttccgct      360

cctgcctcct gtcggatttt taatttctgc gcacccccag tcaaattaaa tcaaccaaca      420

aaaagcaggg catcccccct ggaagcagcg tcttatttta ccttgttctc ccacttcctg      480

aagatgctaa actcctggtg gactgcagag gagagggatt cagtcttctc ctgatgtcga      540

ttgcgatttc tgctgggagc tcaagacggg cgagctgccc gagatctctt cgagataccc      600

caggggagga ggagatgggc aggatttagt aggacaactc ggttactaat gacttggcgg      660

ctggctgcga ccccccggga aatcaggtgc aagcatgtac ctgagttgac accgaaggtg      720

cctaaagatg ctgagcggcg tttggttcct cagtgtgtta accgtggccg ggatcttaca      780

gacagagagt cgcaaaactg ccaaagacat ttgcaagatc cgctgtctgt gcgaagaaaa      840

ggaaaacgta ctgaatatca actgtgagaa caaaggattt acaacagtta gcctgctcca      900

gcccccccag tatcgaatct atcagctttt tctcaatgga aacctcttga caagactgta      960

tccaaacgaa tttgtcaatt actccaacgc ggtgactctt cacctaggta acaacgggtt     1020

acaggagatc cgaacggggg cattcagtgg cctgaaaact ctcaaaagac tgcatctcaa     1080

caacaacaag cttgagatat tgagggagga caccttccta ggcctggaga gcctggagta     1140

tctccaggcc gactacaatt acatcagtgc catcgaggct ggggcattca gcaaacttaa     1200

caagctcaaa gtgctcatcc tgaatgacaa ccttctgctt tcactgccca gcaatgtgtt     1260

ccgctttgtc ctgctgaccc acttagacct cagggggaat aggctaaaag taatgccttt     1320

tgctggcgtc cttgaacata ttggagggat catggagatt cagctggagg aaaatccatg     1380

gaattgcact tgtgacttac ttcctctcaa ggcctggcta gacaccataa ctgtttttgt     1440

gggagagatt gtctgtgaga ctccctttag gttgcatggg aaagacgtga cccagctgac     1500

caggcaagac ctctgtccca gaaaaagtgc cagtgattcc agtcagaggg gcagccatgc     1560

tgacacccac gtccaaaggc tgtcacctac aatgaatcct gctctcaacc caaccagggc     1620

tccgaaagcc agccggccgc ccaaaatgag aaatcgtcca actcctcgag tgactgtgtc     1680

aaaggacagg caaagttttg gacccatcat ggtgtaccag accaagtctc ctgtgcctct     1740

cacctgtccc agcagctgtg tctgcacctc tcagagctca gacaatggtc tgaatgtaaa     1800

ctgccaagaa aggaagttca ctaatatctc tgacctgcag cccaaaccga ccagtccaaa     1860

gaaactctac ctaacaggga actatcttca aactgtctat aagaatgacc tcttagaata     1920

cagttctttg gacttactgc acttaggaaa caacaggatt gcagtcattc aggaaggtgc     1980

ctttacaaac ctgaccagtt tacgcagact ttatctgaat ggcaattacc ttgaagtgct     2040

gtacccttct atgtttgatg gactgcagag cttgcaatat ctctatttag agtataatgt     2100

cattaaggaa attaagcctc tgacctttga tgctttgatt aacctacagc tactgtttct     2160

gaacaacaac cttcttcggt ccttacctga taatatattt ggggggacgg ccctaaccag     2220

gctgaatctg agaaacaacc atttttctca cctgcccgtg aaaggggttc tggatcagct     2280

cccggctttc atccagatag atctgcagga gaacccctgg gactgtacct gtgacatcat     2340

ggggctgaaa gactggacag aacatgccaa ttcccctgtc atcattaatg aggtgacttg     2400

cgaatctcct gctaagcatg caggggagat actaaaattt ctggggaggg aggctatctg     2460

tccagacagc ccaaacttgt cagatggaac cgtcttgtca atgaatcaca atacagacac     2520

acctcggtcg cttagtgtgt ctcctagttc ctatcctgaa ctacacactg aagttccact     2580

gtctgtctta attctgggat tgcttgttgt tttcatctta tctgtctgtt ttggggctgg     2640

tttattcgtc tttgtcttga aacgccgaaa gggagtgccg agcgttccca ggaataccaa     2700

caacttagac gtaagctcct ttcaattaca gtatgggtct tacaacactg agactcacga     2760

taaaacagac ggccatgtct acaactatat ccccccacct gtgggtcaga tgtgccaaaa     2820

ccccatctac atgcagaagg aaggagaccc agtagcctat taccgaaacc tgcaagagtt     2880

cagctatagc aacctggagg agaaaaaaga agagccagcc acacctgctt acacaataag     2940

tgccactgag ctgctagaaa agcaggccac accaagagag cctgagctgc tgtatcaaaa     3000

tattgctgag cgagtcaagg aacttcccag cgcaggccta gtccactata acttttgtac     3060

cttacctaaa aggcagtttg ccccttccta tgaatctcga cgccaaaacc aagacagaat     3120

caataaaacc gttttatatg gaactcccag gaaatgcttt gtggggcagt caaaacccaa     3180

ccacccttta ctgcaagcta agccgcaatc agaaccggac tacctcgaag ttctggaaaa     3240

acaaactgca atcagtcagc tgtgaaggga aatcatttac aaccctaagg catcagagga     3300

tgctgctccg aactgttgga aacaaggaca ttagcttttg tgtttgtttt tgttctccct     3360

ttcccagtgt taatggggga ctttgaaaat gtttgggaga taggatgaag tcatgatttt     3420

gcttttgcaa gttttccttt aaattatttc tctctcgctc tcctcccctc cttttttttt     3480

tttttttttt tttctttttc ccttctcttc ttaggaacca tcagtggaca tgaatgtttc     3540

tacaatgcat ttcttcatag attttgttta tggttttgtt tcttttttct tctttgtttt     3600

tcagtgtggg agtgggaaga ggagattata gtgactgaag aaagaatagg caaacttttc     3660

aaatgaaaat ggatatttag tgtattttgt agaagatctc caaagatctt ttgtgactac     3720

aacttctttt gtaaataatg atatatggta tttccatcgt cagttaccga gtatagccac     3780

tgggtatcac tactttgtgt taaagtgcct tcgcacttta agtacattac ttaaatgttg     3840

cttttagctt tgataaattg aaaatatttt aatgtgttgt atttttgaaa ttgaaaacac     3900

tgtaaaatag attgatgtgt cagctatatt aagtcaacgt acagtttgct tgagttatag     3960

aaaccagcct gtcatcaaat gattctagtt ctaggacttt gtaggcttaa ctataaaata     4020

tttcctttcc tctgggttta agtgatttta tttaagtcaa ctaaggggat ttaacagtgg     4080

actagaggta ataagccacc tcagtcagga ttaataattc attaataaaa tatatttaac     4140

ccaaaaaaaa aaaa                                                       4154


<210>  1122
<211>  2741
<212>  DNA
<213>  homo sapiens

<400>  1122
ccagccaggg gttcccggtt tcacagagag gaaagtgaca gaagacgtgc ggagggagac       60

gcagagacag aggagaggcc ggcagccacc cagtctcggg ggagcactta gctcccccgc      120

cccggctccc accctgtccg gggggctcct gaagccctca gccccaaccc cgggctcccc      180

atggaagcca gctgtgcccc aggaggagca ggaggaggtg gagtcggctg aatgcccacg      240

gtgcgcccgg ggcccctgag cccatcccgc tcctagccgc tgccctaagg cccccgcgcg      300

ccccgcgccc cccacccggg gccgcgccgc ctccgtccgc ccctcccccg gggcttcgcc      360

ccggacctgc cccccgcccg tttgccagcg ctcaggcagg agctctggac tgggcgcgcc      420

gccgccctgg agtgagggaa gcccagtgga agggggtccc gggagccggc tgcgatggac      480

gccgtcttgg aacccttccc ggccgacagg ctgttccccg gatccagctt cctggacttg      540

ggggatctga acgagtcgga cttcctcaac aatgcgcact ttcctgagca cctggaccac      600

tttacggaga acatggagga cttctccaat gacctgttca gcagcttctt tgatgaccct      660

gtgctggatg agaagagccc tctattggac atggaactgg actcccctac gccaggcatc      720

caggcggagc acagctactc cctgagcggc gactcagcgc cccagagccc ccttgtgccc      780

atcaagatgg aggacaccac ccaagatgca gagcatggag catgggcgct gggacacaaa      840

ctgtgctcca tcatggtgaa gcaggagcag agcccggagc tgcccgtgga ccctctggct      900

gccccctcgg ccatggctgc cgcggccgcc atggccacca ccccgctgct gggcctcagc      960

cccttgtcca ggctgcccat cccccaccag gccccgggag agatgactca gctgccagtg     1020

atcaaagcag agcctctgga ggtgaaccag ttcctcaaag tgacaccgga ggacctggtg     1080

cagatgcctc cgacgccccc cagcagccat ggcagtgaca gcgacggctc ccagagtccc     1140

cgctctctgc ccccctccag ccctgtcagg cccatggcgc gctcctccac ggccatctcc     1200

acctccccac tcctcactgc ccctcacaaa ttacagggga catcagggcc actgctcctg     1260

acagaggagg agaagcggac cctgattgct gagggctacc ccatccccac aaaactcccc     1320

ctcaccaaag ccgaggagaa ggccttgaag agagtccgga ggaaaatcaa gaacaagatc     1380

tcagcccagg agagccgtcg taagaagaag gagtatgtgg agtgtctaga aaagaaggtg     1440

gagacattta catctgagaa caatgaactg tggaagaagg tggagaccct ggagaatgcc     1500

aacaggaccc tgctccagca gctgcagaaa ctccagactc tggtcaccaa caagatctcc     1560

agaccttaca agatggccgc cacccagact gggacctgcc tcatggtggc agccttgtgc     1620

tttgttctgg tgctgggctc cctcgtgccc tgccttcccg agttctcctc cggctcccag     1680

actgtgaagg aagaccccct ggccgcagac ggcgtctaca cggccagcca gatgccctcc     1740

cgaagcctcc tattctacga tgacggggca ggcttatggg aagatggccg cagcaccctg     1800

ctgcccatgg agcccccaga tggctgggaa atcaaccccg gggggccggc agagcagcgg     1860

ccccgggacc acctgcagca tgatcacctg gacagcaccc acgagaccac caagtacctg     1920

agtgaggcct ggcctaaaga cggtggaaac ggcaccagcc ccgacttctc ccactccaag     1980

gagtggttcc acgacaggga tctgggcccc aacaccacca tcaaactctc ctaggccatg     2040

ccaagaccca ggacatagga cggacccctg gtacccagaa gaggagttct tgctcactaa     2100

cccggatccg cctcgtgccc ctgcctcctg gagcttccca ttccaggaga aaaggctcca     2160

cttcccagcc cttccttgcc cctgacattt ggactcttcc cttgggccga ccactctgtt     2220

ctcattctcc ttcccaccaa catccatccg tccttctcag acaaaccact cactgggtac     2280

cccacctcct ctctcatatg cccaacacga ccactgcctc cctgccccca cacctgcacc     2340

caaacagaca catcaacgca ccccactcac agacacccct taccccaccc ccactgtaca     2400

gagaccaaga acagaaattg tttgtaaata atgaacctta ttttttatta ttgccaatcc     2460

cctaagatat tgtattttac aaatctccct cttcccttcg cccctccctt gttttatatt     2520

ttatgaagtt agtgcgggct ttgctgctcc ctggcccagg aaagagggac tacctgaccc     2580

tcacctggca cccccctgct gctgcccaag ccgctgggcc tttttaattg ccaaactgct     2640

ctcttcatca gctcagcaca tgctttaaga aagcaaaacc aaaaaaaaaa aaaaaaagat     2700

gcagcatcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                         2741


<210>  1123
<211>  4475
<212>  DNA
<213>  homo sapiens

<400>  1123
gtgggtccct gtgacgtcac tgccggccgg acgccatctt gctggtttgc ggccggtctt       60

ggatgaagcg gcggccgtgg tgagagcgtg gggaagggtg gggtgagggg gcgaggccgc      120

agctagggcg gcgaaactct cctcccctcg gccccaccgc gtgggacggc gtgaacgtgg      180

tgtcggaggg atgtcagcct tctctgaggc ggcgctggag aagaagctgt cggagttgag      240

caactcgcag cagagcgtgc agaccttgtc cctgtggctc attcaccacc gtaaacactc      300

gcgtcccatc gtcaccgtgt gggagcggga gctgcggaaa gccaaaccaa acaggaagct      360

tacttttctc tacctagcca atgatgtcat acagaacagc aagaggaagg ggccagagtt      420

tacaaaagat tttgcaccag ttatagtgga ggcttttaag catgtttcaa gtgaaactga      480

tgaaagttgt aagaagcacc ttggaagagt gttatctatt tgggaagaaa ggtctgttta      540

tgaaaatgat gtattagaac aacttaaaca agctctgtat ggtgataaga agcctaggaa      600

gcgaacttat gaacagataa aggtggatga aaatgaaaac tgttcctctc tgggatctcc      660

aagtgaacca ccacagactc tagatctcgt tagagcatta caagatctgg aaaatgcagc      720

ctcaggtgat gcagcagttc atcagaggat agcttcttta cctgttgaag tccaagaagt      780

atctctatta gataaaataa cagataaaga atctggagaa aggctttcca aaatggtaga      840

ggatgcgtgt atgttgctgg cagattacaa tggcagattg gcggcagaaa tagatgatag      900

aaagcaactc actcgaatgt tagcagattt tcttcgttgt caaaaggaag cccttgcaga      960

gaaagagcat aaattggaag agtacaagcg caagctagcc agagtttccc tggtgcgcaa     1020

agaactcagg tcccggatcc agagcctgcc agacttatct cgattgccca atgtcactgg     1080

cagccacatg cacctgccct ttgcgggaga catctacagt gaagattgat ggaccagcct     1140

ctttccaggt cccaggactt tgcaagagat ggagacaggt taggtggata gtcctgtagt     1200

gttatttttg tatattgttg agaaagaaac actaacaaaa ggaacaacga gtaatttata     1260

aaattgttta aaatgttggt ttgtttacta ttttattggt aaattaacat gacttaattt     1320

gaacaaagtg atgatttgtg tgtattaata agctcacaaa tagtgattat tttcaaaaga     1380

tctttttgta aatttttttt ttgatccaag gccttgtgag aaatctcttg tttgtatttc     1440

ttcaggtatt ttcaattgtt tttctttatt ttcttcagca tttaatcact gtatactatg     1500

taattcctga aggggaagaa ctaattagga gttgattgag actttattat ggtatagtta     1560

ggacttgatt gtagaaggga ctaaatgttc caacataatc tttacccttc tccccaaaca     1620

aaatatcaat tctgtgtctc tacatgcctt tgattcctta gaggtcggta atttaacata     1680

aaacagggat gtcactttga ggggcagatg aaagtctaga gaactgttcc ttaatagcat     1740

tgtaaaagtt ccattccaac tgccagtgta gattttaaaa gtgttaaata gtgactccct     1800

tgattaaact gtttgtaatt atttgagtag attaataatg aaaatacttt ggaaataata     1860

tacattttga cattctacca agaggacaac tttggttctg gaactggttt ctatttgtca     1920

aatcagtttc cttttaacat aattaatccc tttaacaaaa agccgtctat gggattaaaa     1980

gacacgtgaa atgatacttt tattattccc ttgctcatat aactttaaaa ataatacttt     2040

tagctctaat agctcaagaa cacaatattc gttaatgttc agtaaagtag cctgagacat     2100

tttcaatgtt tccttaaggt ttttgaatga ctgtatattt ggcagttaag cagtgccaca     2160

ctacagggta gatatggtaa attttatatt tgtatattta cagttacaaa acaaatgtac     2220

ttttaccttt tatttctgac cctgtgtgtt agagcagttg catgctctcc tgctgttaaa     2280

aacacattgt taagctgtgg atttgtactc aataatgact taggataaac atttattttc     2340

attcattgct ttacatacta gacatttttc ttctctttgt aagtagattc aaattagata     2400

gtcaataaaa catcttgaaa atcccacaag ccaattatgt ctctctagtc tgaatggctt     2460

cattgtttct ttctcagtat tagaaattat agttacaatg aattgcatat gaagaaggca     2520

gacatttatt tttaatagcc aagtagttct gcaaatagtt cttttaacaa tttgacctct     2580

ctccaaaaca gagacacata taagtagtgc tcatccatgc actactaata atacatggct     2640

tattccaaag tttttagtca acttttggga cttggggtgc attttctcac agaaagaata     2700

gtagttaggt tccctaacac taccgctgat agctcacctg ggaactgaat ccacctaacc     2760

atgaatgtcc ttcacttgta acgtggttca caggttacta atcatagatc ctgaccagca     2820

tttgtaacac tgctctaact aggacacagc atgcagcagc cacactcaca ccctgggatg     2880

tctgtgtacc tctgtcccta ggtgtaggaa atggaagaaa aagattcagc caagtgggga     2940

ggtgacagat gcacaattat gaaacctggt tgtacatgtt atgaaagtat actaagtaag     3000

ttagttttta ttattaatgt gaaagcaaaa acttgtatgt taacttattt tcaatatctt     3060

gaccttattt atgatctgct aaagtggtga tttatccatt caaaatatat atttttttcc     3120

atttaaaact aatttataaa ctatgtactc ctgggaagat ttgaaatctt ttagaagttt     3180

gttgaaatat tttcaccatt tcagacagac ttctgactta gatactgatt ttaatgccag     3240

tatctgctct aaatatttat gataaaaatg cattattttt ttaaagagct tgatgagatt     3300

tgtgataagt gatagtactc aaaaacctga atcccacccc tcgaccaatc ctccacaaac     3360

ttcagttgtt ggttaacgta ttaactgaac acagacaata cagtctgatt tagaagtcat     3420

cttttcagcc gtgtgataat taacatggta agccttagca gcaaacattc ttcctaaaag     3480

gaagacttca ttttctcaag aaatgggatt agttgggggt attataatac caaattgtaa     3540

atcatgagcg ttttctccac tgtgcacctg aggcagatca tgcatctttg agtgcagttt     3600

ggtctgaccc ctcaagagaa aagcatggtg ccgtagggct gctatggttt gaatggatgc     3660

catcactctt ttctccacat acagtgcaga gagctgtctg gagtcacaat ctgaacagat     3720

tctcgggcgc tccttctctc cttccatcac tacagtaagt aaaaggacca tagaggggaa     3780

ccaggaatct gagaatcagc tgtgctcaat agccaacctc cctgtccaga tgcagctatt     3840

ttggtatctc ctatcacatg cactctgaat cagggttttt ctataagaaa tctttcagaa     3900

tcagcaaaag tggggatgac ccaggcatct tgatttgcaa aatcacaaaa ctaagttgtc     3960

agttatcact gtagatgagc aactcatctt tttaaagtat agttactgaa ctgattctga     4020

gaaatcttta gagagaaaaa actcaacagt acaaattaac taattgggaa agttagaatg     4080

tcctttctga atttttcatt aaaaaaatta cattatctga aataacataa agctactaaa     4140

ctgctttgta ttctattaag aaatagctcc taaggatgta gtcttgtttc atagttgttg     4200

cactatatca aaacttaaaa tgtaagccca gttcttctct gtatagaaag gaaacattgt     4260

gttacttaat gaattattta tacagagcat ttgttgccaa ctgttgttcc agccatccac     4320

acaggagtct gttctgaggt ggcaatagca catgggaaga tgaactttcc ctgtttgttt     4380

acccgttctt ctttggctgt atctgatgac agtataagat gttcttaata aagttttatg     4440

ttctttttga aatgtgaaaa aaaaaaaaaa aaaaa                                4475


<210>  1124
<211>  10826
<212>  DNA
<213>  homo sapiens

<400>  1124
atgaccaatg ggtctgtgtt ttggaccggc gaagcccaat ggcgcgacag ggaaggcggg       60

cccgagatgg gttagggtgt ccttgcaggg tgtctgagct aaacttcacc aaataatagc      120

tgtttgtatt ttggctgctg caggagccat tttagaaata aatatcttcc ttcaatagat      180

gaaaatgaaa atacagaaaa aagagaagca gttgtcaaat ttaaaagttt tgaatcactc      240

cccaatgtct gatgcctctg tcaattttga ctacaaatct ccatccccat ttgactgcag      300

cactgatcaa gaagagaaaa ttgaagatgt tgctagtcac tgtctgcctc agaaggacct      360

gtatactgct gaagaggaag ctgctaccct ttttcctagg aaaatgacat cccataatgg      420

gatggaggac agtggaggag gaggtactgg agtgaagaag aaacggaaga aaaaggagcc      480

aggagaccaa gagggtgcag caaagggaag caaggacaga gagcccaagc caaagaggaa      540

acgagaaccg aaagagccaa aggaacccag aaaggccaag gagccgaaga aggccaagga      600

gcacaaggag ccgaagcaaa aagatggggc aaagaaggca cggaagcccc gggaggcctc      660

gggcaccaag gaggccaaag agaagaggag ctgcactgac tctgcagcca ggacgaagtc      720

caggaaggcc agcaaggagc aaggaccaac cccagtggag aaaaagaaga aaggaaaaag      780

gaaaagtgaa actacagtgg agagtttaga gctggatcag ggcctgacga acccatctct      840

gcggagtcct gaggagtcca ctgagtctac agacagccag aaacgacgct cgggaaggca      900

agtaaagcgc agaaaataca atgaggacct ggacttcaaa gtggtggatg atgatgggga      960

aacaattgct gttcttggag ctggtcgaac atctgcactc tcagcctcta cactggcctg     1020

gcaggcggag gagcctccag aagatgatgc aaacatcatt gagaagatcc tggcatctaa     1080

gactgtccag gaggttcacc caggagaacc tccgttcgac ttggagctgt tctacgttaa     1140

gtatagaaat ttttcctact tacattgtaa atgggccaca atggaagagc tcgaaaagga     1200

tcctcgcatc gcacagaaga tcaagcgatt taggaataaa caagcccaga tgaagcacat     1260

ttttacggag cctgatgaag acttgttcaa tccagactat gtagaagttg atcgcatctt     1320

ggaggtggcc cacaccaagg atgcagaaac aggggaggag gtaacacatt acctggtgaa     1380

gtggtgctca ctaccatatg aagaaagcac gtgggagcta gaggaagatg tagatcctgc     1440

aaaagttaaa gaatttgaat ctcttcaagt tctccctgaa attaagcatg tggagcggcc     1500

tgcttcagac tcctggcaga aacttgagaa gtctcgcgag tataagaaca gtaaccagct     1560

ccgggagtac cagctggaag ggatgaactg gcttcttttt aactggtata acagaaaaaa     1620

ctgtattttg gctgatgaga tgggcctagg gaaaaccatc cagtccatca cattcctttc     1680

agaaatattt ctgagaggaa tccacggccc ttttctcatt atcgcccctc tctccaccat     1740

cactaactgg gagcgggagt tccggacatg gacagagatg aatgccattg tgtaccacgg     1800

cagccagatc agcaggcaga tgatccagca gtatgaaatg gtgtacagag acgcccaggg     1860

aaaccccctt tcaggagtct tcaagttcca cgtcgtcatc acaacatttg aaatgatcct     1920

agcagactgc ccagagttga agaagattca ctggagctgt gtgataattg atgaagccca     1980

cagactgaag aataggaact gcaaacttct ggagggtcta aagcttatgg ccctggaaca     2040

taaagtgctt ctcactggaa cacccttgca gaactctgtg gaggagctct tcagtttgtt     2100

aaattttctg gagccatcac agtttccttc agagaccgct ttcttggagg aatttggaga     2160

tctgaaaaca gaggagcagg taaagaaact gcagtctatc ctaaaaccaa tgatgcttcg     2220

gcggctgaaa gatgatgtgg aaaagaacct tgctcccaaa caagagacga tcattgaggt     2280

ggaactgacc aatatccaga aaaagtacta ccgtgccatc ctcgagaaga acttttcctt     2340

cctgaccaag ggggcaaatc agcacaacat gcccaatctc atcaacacca tgatggagct     2400

gaggaagtgc tgtaaccatc cctacctgat caatggagca gaggagaaaa ttctagaaga     2460

tttccgaaaa acccacagcc ctgatgcccc tgactttcag ctgcaggcca tgattcaggc     2520

agcaggaaag cttgtgttga ttgataaact actccctaag ctgattgcag gtggccacaa     2580

agtactcatc ttctcccaga tggtgcgctg cctcgacatc ctagaagatt acctcatcca     2640

gagaagatac acctatgagc gaattgatgg gcgagtacgg ggaaacctgc gccaggcagc     2700

catcgaccgg ttctgtaagc cagattcaga ccgctttgtc tttcttctgt gcaccagagc     2760

gggaggcctg gggatcaatc tcacagctgc tgatacctgc atcatatttg attctgactg     2820

gaacccacaa aatgacttgc aggctcaggc ccgatgtcac cgcataggcc agagcaaagc     2880

tgtgaaggtg tatcgcctca tcactcgaaa ttcctacgag cgcgagatgt ttgacaaggc     2940

cagcctaaag ctggggctgg acaaggctgt tcttcaggac atcaaccgaa agggcggcac     3000

caatggggta cagcagctct caaaaatgga ggtggaggac ctactccgga aaggtgctta     3060

tggagcctta atggatgaag aagatgaagg ctccaagttc tgtgaagaag acatagacca     3120

gattctgcag aggcgaacgc acaccatcac catccagtct gaggggaaag ggtccacttt     3180

tgccaaggct agctttgtgg cttcaggaaa cagaacagat atttccttag atgatcctaa     3240

cttttggcag aaatgggcta aaatagctga actagacact gaagcaaaga atgaaaagga     3300

aagcttagtg atcgaccgac ctcgcgtgag aaagcagacc aaacactaca actcgtttga     3360

ggaagacgag ctcatggagt tttcagagtt agacagcgac tcagacgaaa ggcccacgag     3420

atccaggcgc ctcaatgaca aagccaggcg ctacctccga gcggagtgct tccgggtaga     3480

gaagaacctg ctcatctttg gctggggccg gtggaaggac atcctgactc atggccgatt     3540

caagtggcat ctgaacgaga aggacatgga gatgatttgc cgtgccctcc tggtgtactg     3600

tgtcaagcat tataaggggg acgagaagat caagagtttc atttgggaac tgatcacacc     3660

taccaaagat gggcaagccc agaccctcca gaaccactca ggcttatctg ccccagtccc     3720

cagagggagg aaggggaaga agacgaagaa ccagttgcta atcccagagc taaaggatgc     3780

agattggcta gccacctgca accccgaggt ggtcttgcat gatgatggct ataagaaaca     3840

cctcaaacag cactgcaaca aagtactttt gcgagtccgg atgctgtact acctaaaagc     3900

tgaaatactg ggagaagcag ctgagaaagc atttgaagga tctcctgcca gggagctgga     3960

tgtacctctg cctgacatcg actacatgga gatcccagtg gactggtggg atgctgaagc     4020

cgataagtca cttctcattg gcgtgttcaa gcatggttat gaaaggtaca atgccatgcg     4080

agcagaccca gcactttgct tcctggagaa agttgggatg cccgatgaga agtccctttc     4140

tgcagaacag ggtgttacag atgggacctc agacattcct gaaagaggca acacagataa     4200

agaagacaat gctgaggaca aagtagatgg cctccagaaa caaacggaga gttccagtga     4260

tggaggtgat ggcgttttta gcgaaaagaa ggatgacagc cgggcagccc aggatggctc     4320

cgacccagac aaatcgccct ggccagtttc ctccgccctc acagctcgtc tcagacgtct     4380

ggtcactgtt taccagcgct gcaaccgcaa ggaactgtgc cggcctgaaa ttctgggacc     4440

aggtaaccaa ggatattggg ttcaggaaga gatgttcagg agaacctcag aaatggacct     4500

catcaacaag gaagcccaaa agaggtggac taggagagaa caagcagact tctatagaac     4560

agtgtcttcc tttggtgttg tttacgatca agaaaagaaa acctttgact ggacacagtt     4620

ccgcatcatt tcccgtttgg acaagaagtc ggatgagagc ctggaacagt atttttatag     4680

ttttgtggcc atgtgccgga atgtctgtcg tctacccaca tggaaagatg gcggtccccc     4740

agataccacc atctacgttg aacccatcac tgaggaacgt gctgcaagaa ctctgtaccg     4800

cattgaactg ttacggaaag tccgagagca agtgctcaag tgccctcagc tgcatgaacg     4860

cctccagctg tgcaggccca gcctctacct cccagtctgg tgggagtgtg ggaagcatga     4920

tcgagacctg ctcatcggca ctgccaaaca tgggctgaac cgcactgact gttacatcat     4980

gaacgacccc cagctgtcct tcctggatgc ctatagaaac tatgcccagc ataaaagatc     5040

tggcacccag gcaccaggaa atctctgttg cctttaccag accaactcca agttatatga     5100

atctcttaca tattctcaaa tgagtaggac ttcagagtcc cttgaaaatg aacctgaaaa     5160

tctagtgaga gtagaaagca gagatgatca tctcagcctg cctgatgtga catgtgaaaa     5220

ctttatttct aaagttcagg atgtcatttc catcaaccat gatgaaagtc tgctgcctga     5280

gtccttagag agcatgatgt atggtaagaa ggtgctcagc caagaaccaa gctcttttca     5340

ggagagccca agtaccaata ctgaatctag aaaagatgtt attaccatct caataagcaa     5400

agatgggaac tgccagtctg gtggccctga ggcagaaata gcttctggcc ctacttttat     5460

gggtagctta gaagcaggag gagtagctca agcaaacatc aaaaatggaa aacatttgtt     5520

gatgtctatt tcaaaggaag gggagctctg ctgcagtgag gcaggacaga gacctgaaaa     5580

cattggccag ctggaagcca agtgtttagc ttccccttcc ttgaatccag gaaatgaaag     5640

tgggtttgta gatatgtgca gtcttagtgt ctgtgactcc aaaagaaacc tgtcatcaga     5700

tcagcaatta attgatttat tggaaaacaa aagcttagaa agtaaattga ttttgagtca     5760

gaaccacagt gatgaggagg aagaagagga ggaaaacgag gaggaaaact tagccatggc     5820

agtaggcatg ggggaaaggc cagaggtatt gcatctcacg gagcccacta ctaacatctc     5880

aagggaaaag aaccaaggct tccaagatga aaccaagaaa ggaagcttag aggtggcaaa     5940

ccagactcct gggctacaga gggctttccc cgctccagca gcctgtcagt gccactgcaa     6000

acacatggag aggtggatgc atggcctcga gaatgatgaa tttgaaatcg agaaacccaa     6060

ggcttatatc ccagatctgt tcaaaagtaa aaccaatact atcgccatgg agggtgaacc     6120

cactgctatt ccatcacagc cgtttaaagt gaagcatgag cttttaaaag aaccttggaa     6180

agaaagtgca gaggggcaaa acgttttccc cacatatcct cttgaaggaa gtgagctcaa     6240

atcagaagac atggattttg agaataaaga tgattatgat agagacggaa actgccatag     6300

tcaagattat ccagggaagt actctgaaga ggagagcaag agctcaacat cgggcatcac     6360

aggagacatt ggggatgagc tacaggaggc tcgagctccc actattgctc agctgctaca     6420

ggagaaaact ctctattcct tctctgagtg gccaaaggac cgcgtgataa ttaaccgcct     6480

agataatatc tgccacgtgg tgttaaaggg gaagtggccc tctagccagc agtatgagcc     6540

ctcaggcaca ctgcccaccc cggtattaac cagcagtgct ggttctcgaa ccagcctctc     6600

agagccggaa gcagcagaac acagcttcag caacggcgca gcattggcgg cccagatcca     6660

caaggagagc ttcttagctc cagtattcac aaaggatgaa caaaagcaca ggcgtcccta     6720

tgagtttgag gtggagaggg atgcaaaggc tcggggcctg gagcagttct ctgccaccca     6780

cgggcacacc cctatcatcc tcaatggctg gcatggggag tcagctatgg acctctcctg     6840

ctcatcagag gggtccccag gagccacatc ccctttccca gtgagcgcca gcacccctaa     6900

gattggggct atcagttcac ttcagggagc ccttggcatg gacttgtctg ggattctgca     6960

agctggcctg atccatcctg tgactggaca gattgtcaat ggaagcctca gaagagatga     7020

tgcagccacg aggaggcgga gagggaggcg gaaacatgtt gaaggaggga tggacctcat     7080

ctttttgaag gagcagacac ttcaggcggg aatcttggaa gtccatgaag acccagggca     7140

ggccaccttg agcaccacac accctgaggg gccagggcct gccacctcgg ctcctgagcc     7200

agctacggca gccagcagcc aagccgagaa atccattccc agcaagagtc tgcttgactg     7260

gctaaggcag caggctgact actccttaga agttcctggc tttggggcaa atttttcaga     7320

caaaccaaag cagaggaggc cacgctgtaa agaacctgga aaattagatg tcagctccct     7380

gagcggggaa gagagagttc ctgccatccc caaggagcca ggactgaggg ggtttcttcc     7440

agaaaacaag ttcaatcaca ctctggctga gcctattctt cgagatacgg gcccccgcag     7500

gagggggagg cggcctcgga gcgaactcct gaaggctcct tccattgtgg cagactctcc     7560

ctctggaatg gggccactgt tcatgaatgg actgattgct gggatggacc tggtaggact     7620

tcagaacatg agaaatatgc caggcatccc cctcaccggg ctggtggggt ttccagctgg     7680

ctttgccacg atgccaacag gtgaagaggt caaaagtacc ctgagcatgc tgcccatgat     7740

gctgccaggc atggctgctg tgccccagat gtttggtgtt gggggactcc tcagtccacc     7800

catggcaacc acctgcactt ccactgctcc ggcgtctcta tcaagcacaa cgaaaagtgg     7860

tacggcagtg actgaaaaga ctgcggaaga caagccgagt agccatgatg tgaaaacaga     7920

cactttagct gaggacaagc ctggtccagg tccattttct gatcagtctg aacctgcaat     7980

aactactagt agtcctgtgg cttttaaccc atttctcatc ccaggagtat ctcctggact     8040

catttaccca tccatgttcc tctcccctgg tatgggcatg gctctgccag ccatgcagca     8100

ggccagacac tcggaaatag taggtctgga gagccagaag aggaagaaga agaagacaaa     8160

gggggacaac cccaactccc acccagagcc tgctcccagc tgtgaaaggg agcccagcgg     8220

tgatgagaac tgtgccgaac ccagtgcccc tttgcccgca gagagagaac atggggcaca     8280

ggctggggag ggggcactca aagactccaa caacgacacc aattagaact tttttcattt     8340

aagaaattat tgtgacttgt aagtttctta tcccataaag gtttgttact tccctcactt     8400

cacctccata agaacctgtg tttccataag taagattacg tacctgattt cctgtctgag     8460

aactatggta acagatgtta atagttgcag ggtctcacca cttcattaga taagtgttgt     8520

ctacctagtc taggaggcac agaattctca ttctgttatc cagttcattc cagcaatcat     8580

agttaataca gtacttggtg acacgcccta cccccttctc ttccaagttt cccactcact     8640

tgaggaggaa aaatggcaaa agaaagctgt ctagggtttt accattgaag ggtggaagaa     8700

cagagacaaa gaggagctct ttttctgtga gctgggttgc acaggaagaa tgtcacaggg     8760

aaccaaaaag cacagaaaaa ggaagtgctg gtgcatattt ttgagttaaa atatttccct     8820

attttatcat gattactaag tgagtagtat agacagaagt atataactaa tggttgaaaa     8880

tacatatatt catttcttta taaaaaacaa aaaccttacc ggtagtaata taatttcccc     8940

cttggtggtt tttcagacac ctgcagcaag aagaaatact gactgactag gcattatttt     9000

ctatacatcc ctctcaccag tgaaaagatt cctcttgctg cgagaaagct ttacccacca     9060

tgagttattg ctgtcgacgg gggtggggca aggacccgcg ctccgtagag ctacacgctg     9120

cttcacaagc acacggctag cgctctgctc tcacctggtt cgcttacaga tttctctagc     9180

cattaatttg cctctctgtg tttaaagagc accaggaccg aatggatttt cacttcaggc     9240

tttccttcac caagaataag gttctttctg gagcctgcaa gaagacagtt gcccaacact     9300

ttgacacttg ctagtaggtc ctttgatcaa gagtgtctga ggctgtcaaa tgtgtgccac     9360

cctttataat acagctatga aaagttactt ctccattaat ttctccattc tgtttatatc     9420

ttacagttgg acccaaattc caaattatca gttaatcgaa actacattgc aagtcaacat     9480

tattttctct tcttcctcag cttctccatg tttaggaact gagaaagaac ctgcctaagc     9540

agcacttccc catgtccttt caccttcatg ttaacgtccc ttctgatggt ctcactcttc     9600

acaggtagtt cacactctga gacttgaagt aagctcatgg ttcagtactc tgggggcgca     9660

gggctgcgca ggacccttgg aaatgttgca agtgttacta gtaccagttt cactttttgt     9720

tgtcacaatt tactgtattt tttacttttt ctgttacagt tttgctaatt tatcagaagg     9780

tccaaaagtc tgacataact atttcatttt gcattattta tttatgatgc ttttttcatt     9840

gtcttttata catttgggat tataaattat gtaaatgtta aaatgagcat ctcaaagaag     9900

tctgttaaat catgactgaa aaaaatcaat cagatgtatc ttcaaaaagt ggagtcccag     9960

ttttatgaat cagagatata aaccagaaat tctataactg atcatagaag aagaatccag    10020

taattgaaca aatcctattt aatgacatcc ttgtagcata gatggtctat aatgctgacc    10080

acagatttct tagaaatgct gctctctcta tttaactaac attttgttca gttttgcctc    10140

cagtggaagc agaaagggtt ttttcagctg ttaaatccta aaaatcaata taatttattt    10200

atgtaagaaa aataactcaa tcaatatatt tttgaacctt ttaagtacta attttctttt    10260

tatcaagtag aaaaaaaaat gtatttgccc taaatcctta aaatacaaat gctataaaaa    10320

ttcctgtatc ttgaaagcct tactgcaaat gagtattata gacatccagc agagtctggt    10380

tttctttgtt gtcgttgtgt tgttgttgtt ttgtatggaa aagctgcttt ccccgggttc    10440

cacttataac ctccggtagg tcacagggtt caatgtggat ctgacttaaa aacccaccag    10500

catgctcaat cccttgttat ccttatggaa tctgtatgtt aactctctgg gtgttcaggc    10560

ttctatttga ctgctgttgt gaccctgttt gcaaaatgaa tatgacactc tgtggattat    10620

ttgctctgta aggcacaagt gcttcttatg attattttga cgtttccaag agcaaaagcc    10680

aaatttaaac tctcttcagc aaacttgagc cttttcatct aattccatgt cactcacggc    10740

cataactttc cttgaccatt cttcacccca tgtcttacat aataaattgt ggtcttgatc    10800

ctggatttaa aaacaaaaaa aaaaaa                                         10826


<210>  1125
<211>  1626
<212>  DNA
<213>  homo sapiens

<400>  1125
ggaaacccaa aaaagggcat aggggcggga acagcccagc gggccgtccc atcggctttt       60

gggtctgtta cccaaagaat gataaagttg gttttatttc aagaagtcga tcaaaaagaa      120

agccccagcg ctctagagct cagctgacgg gaaagggggt gcgcagcctc gagtttgaga      180

gctacccgga gctccaagac aggggtgggt tccagctgcc cgcacgcccc gaccttccat      240

cgtaggccgg accatgggaa ccccaaagcc acggatcctg ccctggctgg tgtcgcagct      300

ggacctgggg caactggagg gcgtggcctg ggtgaacaag agccgcacgc gcttccgcat      360

cccttggaag cacggcctac ggcaggatgc acagcaggag gatttcggaa tcttccaggc      420

ctgggccgag gccactggtg catatgttcc cgggagggat aagccagacc tgccaacctg      480

gaagaggaat ttccgctctg ccctcaaccg caaagaaggg ttgcgtttag cagaggaccg      540

gagcaaggac cctcacgacc cacataaaat ctacgagttt gtgaactcag gagttgggga      600

cttttcccag ccagacacct ctccggacac caatggtgga ggcagtactt ctgataccca      660

ggaagacatt ctggatgagt tactgggtaa catggtgttg gccccactcc cagatccggg      720

acccccaagc ctggctgtag cccctgagcc ctgccctcag cccctgcgga gccccagctt      780

ggacaatccc actcccttcc caaacctggg gccctctgag aacccactga agcggctgtt      840

ggtgccgggg gaagagtggg agttcgaggt gacagccttc taccggggcc gccaagtctt      900

ccagcagacc atctcctgcc cggagggcct gcggctggtg gggtccgaag tgggagacag      960

gacgctgcct ggatggccag tcacactgcc agaccctggc atgtccctga cagacagggg     1020

agtgatgagc tacgtgaggc atgtgctgag ctgcctgggt gggggactgg ctctctggcg     1080

ggccgggcag tggctctggg cccagcggct ggggcactgc cacacatact gggcagtgag     1140

cgaggagctg ctccccaaca gcgggcatgg gcctgatggc gaggtcccca aggacaagga     1200

aggaggcgtg tttgacctgg ggcccttcat tgtagatctg attaccttca cggaaggaag     1260

cggacgctca ccacgctatg ccctctggtt ctgtgtgggg gagtcatggc cccaggacca     1320

gccgtggacc aagaggctcg tgatggtcaa ggttgtgccc acgtgcctca gggccttggt     1380

agaaatggcc cgggtagggg gtgcctcctc cctggagaat actgtggacc tgcacatttc     1440

caacagccac ccactctccc tcacctccga ccagtacaag gcctacctgc aggacttggt     1500

ggagggcatg gatttccagg gccctgggga gagctgagcc ctcgctcctc atggtgtgcc     1560

tccaaccccc ctgttcccca ccacctcaac caataaactg gttcctgcta tgatcaaaaa     1620

aaaaaa                                                                1626


<210>  1126
<211>  1885
<212>  DNA
<213>  homo sapiens

<400>  1126
gaaactcccg cctggccacc ataaaagcgc cggccctccg cttccccgcg agacgaaact       60

tcccgtcccg gcggctctgg cacccagggt ccggcctgcg ccttcccgcc aggcctggac      120

actggttcaa cacctgtgac ttcatgtgtg cgcgccggcc acacctgcag tcacacctgt      180

agccccctct gccaagagat ccataccgag gcagcgtcgg tggctacaag ccctcagtcc      240

acacctgtgg acacctgtga cacctggcca cacgacctgt ggccgcggcc tggcgtctgc      300

tgcgacagga gcccttacct cccctgttat aacacctgac cgccacctaa ctgcccctgc      360

agaaggagca atggccttgg ctcctgagag ggcagcccca cgcgtgctgt tcggagagtg      420

gctccttgga gagatcagca gcggctgcta tgaggggctg cagtggctgg acgaggcccg      480

cacctgtttc cgcgtgccct ggaagcactt cgcgcgcaag gacctgagcg aggccgacgc      540

gcgcatcttc aaggcctggg ctgtggcccg cggcaggtgg ccgcctagca gcaggggagg      600

tggcccgccc cccgaggctg agactgcgga gcgcgccggc tggaaaacca acttccgctg      660

cgcactgcgc agcacgcgtc gcttcgtgat gctgcgggat aactcggggg acccggccga      720

cccgcacaag gtgtacgcgc tcagccggga gctgtgctgg cgagaaggcc caggcacgga      780

ccagactgag gcagaggccc ccgcagctgt cccaccacca cagggtgggc ccccagggcc      840

attcctggca cacacacatg ctggactcca agccccaggc cccctccctg ccccagctgg      900

tgacaagggg gacctcctgc tccaggcagt gcaacagagc tgcctggcag accatctgct      960

gacagcgtca tggggggcag atccagtccc aaccaaggct cctggagagg gacaagaagg     1020

gcttcccctg actggggcct gtgctggagg cgaggccgcg gccccagagt ccccgcacca     1080

ggcagagccg tacctgtcac cctccccaag cgcctgcacc gcggtgcaag agcccagccc     1140

aggggcgctg gacgtgacca tcatgtacaa gggccgcacg gtgctgcaga aggtggtggg     1200

acacccgagc tgcacgttcc tatacggccc cccagaccca gctgtccggg ccacagaccc     1260

ccagcaggta gcattcccca gccctgccga gctcccggac cagaagcagc tgcgctacac     1320

ggaggaactg ctgcggcacg tggcccctgg gttgcacctg gagcttcggg ggccacagct     1380

gtgggcccgg cgcatgggca agtgcaaggt gtactgggag gtgggcggac ccccaggctc     1440

cgccagcccc tccaccccag cctgcctgct gcctcggaac tgtgacaccc ccatcttcga     1500

cttcagagtc ttcttccaag agctggtgga attccgggca cggcagcgcc gtggctcccc     1560

acgctatacc atctacctgg gcttcgggca ggacctgtca gctgggaggc ccaaggagaa     1620

gagcctggtc ctggtgaagc tggaaccctg gctgtgccga gtgcacctag agggcacgca     1680

gcgtgagggt gtgtcttccc tggatagcag cagcctcagc ctctgcctgt ccagcgccaa     1740

cagcctctat gacgacatcg agtgcttcct tatggagctg gagcagcccg cctagaaccc     1800

agtctaatga gaactccaga aagctggagc agcccaccta gagctggccg cggccgccca     1860

gtctaataaa aagaactcca gaaca                                           1885


<210>  1127
<211>  3647
<212>  DNA
<213>  homo sapiens

<400>  1127
gcagttccgc aatcccggcc gctccgggaa gtcgcgcatg cgtagtctcg gccccgggct       60

gccgcgccag cccgtctccg cggcggggga ccgggctgcc ttggcccctc agcgctcgcg      120

tcttttccgg cagttggaac gcttcctgtt gtcctcaccc gtaaccgcct gttgccccct      180

gtctcagagt ccctcacgcg tcccctcccg tctttggctc gttggctgcc gccgccgggg      240

cttcgccagc cttcaagtcg agactactgg ccgaaggggc gtctgcggct ctccgccgtc      300

cccagccctg cctctccctg ggctctgcag ccatggcaat gacaggctca acaccttgct      360

catccatgag taaccacaca aaggaaaggg tgacaatgac caaagtgaca ctggagaatt      420

tttatagcaa ccttatcgct caacatgaag aacgagaaat gagacaaaag aagttagaaa      480

aggtgatgga agaagaaggc ctaaaagatg aggagaaacg actccggaga tcagcacatg      540

ctcggaagga aacagagttt cttcgtttga agagaacaag acttggattg gaagattttg      600

agtccttaaa agtaataggc agaggagcat ttggtgaggt acggcttgtt cagaagaaag      660

atacgggaca tgtgtatgca atgaaaatac tccgtaaagc agatatgctt gaaaaagagc      720

aggttggcca cattcgtgcg gagcgtgaca ttctagtgga ggcagacagt ttgtgggttg      780

tgaaaatgtt ctatagtttt caggataagc taaacctcta cctaatcatg gagttcctgc      840

ctggagggga catgatgacc ttgttgatga aaaaagacac tctgacagaa gaggagactc      900

agttttatat agcagaaaca gtattagcca tagactctat tcaccaactt ggattcatcc      960

acagagacat caaaccagac aaccttcttt tggacagcaa gggccatgtg aaactttctg     1020

actttggtct ttgcacagga ctgaaaaaag cacataggac agaattttat aggaatctga     1080

accacagcct ccccagtgat ttcactttcc agaacatgaa ttccaaaagg aaagcagaaa     1140

cctggaaaag aaatagacgt cagctagcct tctccacagt aggcactcct gactacattg     1200

ctcctgaggt gttcatgcag accgggtaca acaagctctg tgattggtgg tcgcttgggg     1260

tgatcatgta tgagatgctc atcggctacc cacctttctg ttctgagacc cctcaagaga     1320

catataagaa ggtgatgaac tggaaagaaa ctttgacttt tcctccagaa gttcccatct     1380

ctgagaaagc caaggatcta attttgaggt tctgctgtga atgggaacat agaattggag     1440

ctcctggagt tgaggaaata aaaagtaact ctttttttga aggcgttgac tgggaacata     1500

tcagagagag acctgctgca atatctattg aaatcaaaag cattgatgat acctcaaact     1560

tcgatgagtt tccagaatct gatattctta agccaacagt ggccacaagt aatcatcctg     1620

agactgacta caagaacaaa gactgggtct tcatcaatta cacgtacaag cgctttgagg     1680

gcctgactgc aaggggggca ataccttcct acatgaaagc agcaaaatag tactcttgcc     1740

acggaatcct atgtggagca gagttctttg tataacatca tgcttttcct ctcacactct     1800

tgaagagctt ccaagaagtt gatggaaccc accaatatgt catagtaaag tctcctgaaa     1860

tgtggtagta agaggatttt cttccataat gcatctgaaa aactgtaaac aaagacaacc     1920

atttctacta cgtcggccat aaacagctat cctgctttgg aagagaagca tcatgagcca     1980

atttgatagg tgttttaaaa ataacttgag ttttcctaag ttcatcagaa tgaaggggaa     2040

aaacagccat catccaacat tattgagatt gtcgtgtata gtcatcgaat atcagccagt     2100

tcctgtaatt ttgtgacacg ctctctgcca agcccaccaa gtatttcctt tatagctaaa     2160

agttccatag tactaaggaa ataaagcaat aaagacagtc tcagcagcca ggattctggc     2220

tgaaggaaat gatccgccac cctgagggtg gtgatggtag tttctaccca tacctcagcc     2280

tcaggcgagt ggcttatagc ctccattcat ggtgcacttt atttatggta ctaagataaa     2340

gactgtcaat ccattgattt atctcctcct gtcccccatc taaaataccc atgctgcttt     2400

tctgagtgtt gatgggggtt accagcttga tccactgttg ctcttagaag gcccagaaag     2460

tctttgggca ttgccaagaa atcccggatt atgtggaaaa ccctcacttt ctcttcacgg     2520

ctgtaccaga aaatccctaa gacagatctt gccgtggact agcaatacct gcaagtgctg     2580

ccaatgggaa ctcaatttat tcctgggaac ctaacgagga gagcccaggc ctaggcagga     2640

ggcctggaac cctcttggct aaggtgctgt tcctgttcct gcaaggtctc cagaacccct     2700

ttggaaatgg tgaaggaacc agcccaatag aagtacagag ccagctgaca agtccttgta     2760

aagctcactc ctcagtcctt ggcacagcca tgttttgtct tctctcttgg tatttcttct     2820

ctcccaactt tagccatttt gccttggaat catgattaca attttttcct ttgcagatgc     2880

cttcctgggg gatactcctc cccaccctaa agggtcgcct gcaacttagg cggattgggt     2940

ctctctgctg tggcgttctc tcttgagaga ccctctgaat tttagcacaa agtgccttct     3000

gtttcacagc tgccaccacc tttagaggaa tttcgtcaga aaaatgtgga ggctccatat     3060

taatgcatta ttttttaaaa agttttgata actcttaaag catcatttgc acctatgtgg     3120

gaactttgcc tgttgcaaag tattgtggcc gagctgcagc tgggagcctg ctttctgcca     3180

gtcttgaggt tctgaagatc agctttgaaa ggaaagtatg tcctagctta gccattcaga     3240

agagaaaaat ggaatatcag agttacagtt gtcagtgaaa ctactttgga ttttaacctc     3300

ttagaggaag aaaaaaggtt agggaagtgt caactctgga tgaaggtgat gtgtttgcct     3360

ctcagtcttt cattcatagc ctgctagtga aaaggaagta aatgagattc ttttgtgtga     3420

ctttgtagtc tctttgtatt accaaatagt tggggtgttg actcctgtgt gttttgcaag     3480

aatgtgtggt aagcctgggt aaagagaagg aactgcggtg ttgggagagt ctttgtgttg     3540

gggagtggca ggggatgatt tgtttcaggg gaaaatgccc acattttaac ttttaaactt     3600

ctgaataaac tgtgtaaaaa cagtagtgga aaaaaaaaaa aaaaaaa                   3647


<210>  1128
<211>  4769
<212>  DNA
<213>  homo sapiens

<400>  1128
agaacgtcag ccagtaagcg ccgttcctcc gggagatgtg gaggaggggg gcggcgtgga       60

ggaagagggg gaagttggcg catgcgccta aagctgacgg gtttgaaatg gcttcgatgt      120

tagccgggac ccgactcaga tcgatgctat agaagacaaa caagggaagg ttttttttcc      180

ttttgcatca tggctcaatt tggaggacag aagaatccgc catgggctac tcagtttaca      240

gccactgcag tatcacagcc agctgcactg ggtgttcaac agccatcact ccttggagca      300

tctcctacca tttatacaca gcaaactgca ttggcagcag caggccttac cacacaaact      360

ccagcaaact atcagttaac acaaactgct gcattgcagc aacaagccgc agctgcagca      420

gctgcattac aacagcaata ttcacaacct cagcaggccc tgtatagtgt gcaacaacag      480

ttacagcaac cccagcaaac cctcttaaca cagccagctg ttgcactgcc tacaagcctt      540

agcctgtcta ctcctcagcc aacagcacaa ataactgtat catatccaac accaaggtcc      600

agtcaacagc aaacccagcc tcagaagcag cgtgttttca caggggtggt tacaaaacta      660

catgatacgt ttggatttgt ggatgaagat gtattctttc agcttagtgc tgtcaaaggg      720

aaaacccccc aagtaggtga cagagtattg gttgaagcta cttataatcc taatatgcct      780

tttaaatgga atgcacagag aattcaaaca ctaccaaatc agaatcagtc gcaaacccag      840

ccattactga agactcctcc tgctgtactt cagccaattg caccacagac aacatttggt      900

gttcagactc agccccagcc ccagtcactg ctgcaggcac agatttcagc agcttctatt      960

acaccactat tgcagactca accacagccc ttattacagc agcctcagca aaaagctggt     1020

ttattgcagc ctcctgttcg tatagtttca cagccacaac cggcacgacg attagatccc     1080

ccatcccgat tttcaggaag aaatgacaga ggggatcaag tgcctaacag aaaagatgat     1140

cgaagtcgtg agagagagag agaaagacgt agatcgagag aaagatcacc tcagaggaaa     1200

cgttcccggg aaagatctcc acgaagagag cgagagcgat cacctcggag agttcgacgt     1260

gttgttccac gttacacagt tcagttttca aagttttctt tagattgtcc cagttgtgac     1320

atgatggaac taaggcgccg ttatcaaaat ttgtatatac ctagtgactt ttttgatgct     1380

caatttacat gggtggatgc tttccctttg tcaagaccat ttcagctggg aaattactgc     1440

aatttttatg taatgcacag agaagtagag tccttagaaa aaaatatggc cattcttgat     1500

ccaccagatg ctgaccactt atacagtgca aaggtaatgc tgatggctag ccctagtatg     1560

gaagatttat atcataagtc atgtgctctt gctgaggacc cacaagaact tcgagatgga     1620

ttccaacatc ctgctagact tgttaagttt ttagtgggca tgaaaggcaa ggatgaagct     1680

atggccattg gaggccactg gtctccttcg ttggatggac cagacccaga aaaagatccc     1740

tctgtgttga ttaagactgc tattcgttgt tgtaaggctc tgacaggcat tgatctaagt     1800

gtgtgcacac aatggtaccg ttttgcagag attcgctacc atcgccctga ggagacccac     1860

aaggggcgta cagttccagc tcatgtggag acagtggttt tatttttccc ggatgtttgg     1920

cattgccttc ccacccgctc agagtgggaa accctctccc gaggatacaa gcagcagctg     1980

gtcgagaagc ttcagggtga acgcaaggag gctgatggag aacaggatga agaagagaag     2040

gatgatggtg aagctaaaga aatttctaca cctacccatt ggtctaaact tgatccaaag     2100

acaatgaagg taaatgacct ccgaaaagaa ttagaaagtc gagctcttag ttccaaagga     2160

ttaaaatccc agttaatagc ccgattgaca aaacagctta aagtagagga acaaaaagaa     2220

gaacagaagg agttagagaa atctgaaaaa gaagaggatg aggatgatga taggaaatct     2280

gaagacgata aagaggaaga agaaaggaaa cgtcaagagg aaatagaacg ccagcgtcga     2340

gaaagaagat atattttgcc tgatgaaccg gccatcattg tacatccaaa ttgggctgca     2400

aaaagtggca agtttgattg tagcatcatg tctttgagtg tcctattgga ctacagatta     2460

gaggataata aagaacattc atttgaggtt tcattgtttg cggaactttt caacgaaatg     2520

cttcaaagag attttggtgt ccgtatatac aaatcattac tgtctcttcc tgagaaagag     2580

gacaaaaaag aaaaggataa aaaaagcaaa aaagatgaga gaaaagataa aaaagaagaa     2640

agagatgatg aaactgatga accaaaaccc aaacggagaa aatcaggcga tgataaagat     2700

aaaaaagaag atagagatga aaggaagaaa gaagataaaa gaaaagatga ttctaaagat     2760

gatgatgaaa ctgaagaaga taacaatcaa gatgaatatg accctatgga agcagaagaa     2820

gctgaggatg aagaagatga tagggatgag gaagaaatga ccaaacgaga tgacaaaaga     2880

gatatcaaca gatactgcaa ggagaggccc tctaaagata aggaaaaaga aaagactcaa     2940

atgatcacaa ttaacagaga tctgttaatg gcttttgttt attttgatca aagtcattgt     3000

ggttaccttc ttgaaaagga tttggaagaa atactttata ctcttggact acatctttct     3060

cgggctcagg taaagaagct tcttaataaa gtagtgctcc gtgaatcttg cttttaccgg     3120

aaattaacag acacctcaaa agatgaagag aaccatgaag agtctgagtc attgcaggaa     3180

gatatgctag gaaacagatt attacttcca acaccaacag taaagcagga atcaaaggat     3240

gtggaagaaa atgttggcct cattgtgtac aatggtgcaa tggtagatgt aggaagcctc     3300

ttgcaaaaat tggaaaagag cgaaaaagta agagctgagg tagaacagaa gctgcagtta     3360

ctagaagaaa aaacagatga agatgaaaaa accatattaa atttggagaa ttccaacaaa     3420

agcctctctg gtgaactcag agaagttaaa aaggacctta gtcagttaca agaaaactta     3480

aagatttcgg aaaacatgaa tttacaattt gaaaaccaaa tgaataagac aatcagaaac     3540

ttatctacgg taatggatga aatccacact gttctcaaga aggataatgt aaagaatgaa     3600

gacaaagatc aaaaatccaa ggagaatggt gccagtgtat gataaaatcc atgtagtgat     3660

gaggaatggt gttaaataat gtaatatata aaaatcatga tataagaatg tttgaaggtg     3720

atgcatgttt gattttagta gtataaatgt attttagttc aaatgatgta taaagtttta     3780

tgaatgtgag tttctgcttt tgaaaattgc ttgtaattcc tagccttcaa attattaaac     3840

actccttgag tgaaataatt ttgcattgca aagtgtttta ggatgaactt tgttatagtt     3900

ttaactccaa taaagttcat cagtttaatt gactgtagta tttaattacc aaatttcttt     3960

tattaaaatg cctagaaatt tttaatttat agaattatta ggttttaaaa tttttagttc     4020

atctgttaaa atttcagtca aaatcataaa atagcatgat gcttaatttt tgcaagtttt     4080

ttgaaacttt ttgttttttt tactcatcac caaaaaatcc cctcttgatc agtctctaaa     4140

agcattcatt aaaaattcag ttcaggccgg gcacggtggc tcacacctgt aatcccaaca     4200

ctttgggagg ccgaggcagg tggatcacct gaggttagga gttcgagacc agcctggcca     4260

acatggtgaa acccggtctc tactaaaaat ataaaaatta gctgggcatg gtggtgggtg     4320

cctgtaatcc cagctacttg ggaggctgag gcaggagaat cgcttgaacc caggaggcgg     4380

aggttgcagt cactcaggat catgcagcta cactccagcc tgggcgacaa gagtgaaact     4440

ccatctcaaa aagaaaaaaa aaaaaaatca gtttatttga aagacagtat atcagaaaga     4500

aagaagcaat agagaactag tattgttctt tatgggttag actttacata atattagttg     4560

tcctgatgtc aatgttactg ctttcaatta atttttctac tttcccagaa tagcatctat     4620

attcctttta attttgaggg tttaaaaaaa aatgcagtgt atgtcaaatt tacagtttag     4680

taccaagcca gtagatgtca gtatgatgcc ttaaattaag tcttctttaa ttaaagatat     4740

ttttttaaat taaaaaaaaa aaaaaaaaa                                       4769


<210>  1129
<211>  1836
<212>  DNA
<213>  homo sapiens

<400>  1129
cggggaaggg gtggggtgga ggcgggagcg gagccgggcg ccgccggagc tgcgcgggga       60

gcgctcgctg gctggctggc tggctggctc tccgctgcgc tgcgctgcgc tccggccgct      120

cccgcggccc gtggatgggg gtgtccggct gagccccggg atccgcctcc ctccgccagg      180

acccgcacag ataaactcat cctgaaagtc gctgttgttc tcctgctgag caagaatgga      240

ggccccactg gtgagtctgg atgaagagtt tgaggacctt cgaccctcct gctcggagga      300

cccggaggag aagccccagt gtttctatgg ttcatctccc caccatctcg aggacccctc      360

cctctccgag cttgagaatt tttcttccga aataatcagc ttcaagtcca tggaggacct      420

cgtaaatgaa tttgatgaga agctcaatgt ctgctttcgg aactacaacg ccaagaccga      480

gaacctagct cccgtgaaga accagttaca gatccaagag gaggaggaga cccttcagga      540

cgaggagtaa gaagtcttaa ttgccctctc ctgcttcagt cgagagccct gtagtccttg      600

tctccttgac atagtgctgg tttctgtcta taggtttatg ggctattact ttcattttcg      660

tgttgccagc ggagcagtgc cctggtactt gctgtcatag ctctatatat gtccctttac      720

agtcccctga ggagaacttt cttaaattga aaccttagag gaatgaaggt tttcctagat      780

acaaaatgga atttcaggag cacagtaaat ttcagggtct gtctatctta agctttcttt      840

atatcagtgg aaatccagcg agatattaga aataaaggcc agaaaaaatt aattaaccat      900

gatggatgaa tctatgttat tggactaatt tgcttcaaga aacaccagaa ttttgaaaat      960

cccgaatttt tgacagcccc tcaggcctgg agagttatct acagatgtta ggatatgtcc     1020

acataagaaa gcatctaaac tgaactgaga gcacagcggg ctaccctgga caaagtaaag     1080

gtggaaacta ggtgatgtgg cctttgagta tgcagattcc ttgtatcact tgctcgctac     1140

tttctagggt cttaatagta gtcaagaaaa gggatctgag aaaagtactc tttcaggagg     1200

gactagaaag agaagggggt gatatgttac acaaattaaa gaaggatgtc ttaggcattt     1260

agtaaaaatt cagtggttcc ccgctatcct cgggggatgt gtttttttgt tttgttttgt     1320

tttgtttttt tttgagatga agtttcattc tatcgcccag gctggagtgc aatggcacaa     1380

ttttggctca ctgcaacctc cacctcccag gttcaagcta ttctcctgcc tcagcctcct     1440

gagtagctgg gactacaggt gtgcgccacc atgcccgact aatttttgta ttttgagtag     1500

agatgggagt ttcaccatgt tggccaggct ggtctcgaac tcctgacctg gtgatttgcc     1560

cgccttggcc tcccaaagtg ctgggattac aggcgtgagt caccacacct ggcccatggt     1620

gggggatatg ttttaagacc cccagttaat gcctgaaacc gctgctagta ccaaacccta     1680

atgttttttc ctgtatgtac gtacatatga taaagttcag tttataagtt aggcacagta     1740

agagactaac aacagctcac agcaaaatag agcaattata acaatatatt gtaataaaaa     1800

ttatgtgaat gtgaaaaaaa aaaaaaaaaa aaaaaa                               1836


<210>  1130
<211>  1781
<212>  DNA
<213>  homo sapiens

<400>  1130
cggggaaggg gtggggtgga ggcgggagcg gagccgggcg ccgccggagc tgcgcgggga       60

gcgctcgctg gctggctggc tggctggctc tccgctgcgc tgcgctgcgc tccggccgct      120

cccgcggccc gtggatgggg gtgtccggct gagccccggg atccgcctcc ctccgccagg      180

acccgcacag ataaactcat cctgaaagtc gctgttgttc tcctgctgag caagaatgga      240

ggccccactg gtgagtctgg atgaagagtt tgaggacctt cgaccctcct gctcggagga      300

cccggaggag aagccccagt gtttctatgg ttcatctccc caccatctcg aggacccctc      360

cctctccgag cttgagaatt tttcttccga aataatcagc ttcaagtcca tggaggacct      420

cgtaaatgaa tttgatgaga agctcaatgt ctgctttcgg aactacaacg ccaagaccga      480

gaacctagct cccgtgaaga accagttaca gatccaagag gaggaggaga cccttcagga      540

cgaggaggtt tgggatgctc tgacagacaa ttacatccct tcactctcag aagactggag      600

ggatccaaac atcgaggctc tgaatggcaa ctgctctgac actgagatcc atgagaaaga      660

agaggaagag ttcaatgaga agagtgaaaa tgattccggt atcaacgagg agcctctgct      720

cacagcagat caggtaattg aggagattga ggaaatgatg cagaactccc cagaccctga      780

ggaagaagag gaggttctgg aagaagagga tggaggagaa acttcctccc aggcagactc      840

ggtcctcctg caggagatgc aggcattgac acagaccttc aacaacaact ggtcctatga      900

agggctgagg cacatgtctg ggtctgagct gaccgagctg ctggaccagg tggagggtgc      960

catccgtgac ttctcggagg agctggtgca gcagctggcc cgccgggacg agctggagtt     1020

tgagaaggaa gtgaagaact cctttatcac ggtgcttatt gaggttcaga acaagcagaa     1080

ggagcagcga gaactgatga aaaagaggcg gaaagagaaa gggctgagcc tgcagagcag     1140

ccggatagag aagggaaacc agatgcctct caagcgcttc agcatggaag gcatctccaa     1200

cattctgcag agtggcatcc gccagacctt tggctcctca ggaactgaca aacagtatct     1260

gaacacagtc attccttacg agaagaaagc ctctcctccc tcagtggaag acctgcagat     1320

gctgacaaac attctctttg ccatgaagga ggataatgag aaggtgccta ctttgctaac     1380

ggactacatt ttaaaagtgc tctgccctac ctaaccttgc cctttggagc agcctcgctg     1440

caggaggtca ctgagcaaga gtcattccat cacagggact gcatgagacc atgtaacctc     1500

cgacatgtat ttaaacgtgt atagcttaac ctggattaaa cacgagcaag cgcgcggggt     1560

cctttgccgt tggcttctag tgctagtaat cattggatgc atgatggggc agggccggtg     1620

atggtgcctc ccccttgctg gtgtcaggag aggggaaggc agccgctttc accgctcatt     1680

atgtagtctg gctacagccc tcaaaaacag cttatactct taagactaat tttgaaataa     1740

aaccttcatt taattaatat tcttaaaaaa aaaaaaaaaa a                         1781


<210>  1131
<211>  1836
<212>  DNA
<213>  homo sapiens

<400>  1131
cggggaaggg gtggggtgga ggcgggagcg gagccgggcg ccgccggagc tgcgcgggga       60

gcgctcgctg gctggctggc tggctggctc tccgctgcgc tgcgctgcgc tccggccgct      120

cccgcggccc gtggatgggg gtgtccggct gagccccggg atccgcctcc ctccgccagg      180

acccgcacag ataaactcat cctgaaagtc gctgttgttc tcctgctgag caagaatgga      240

ggccccactg gtgagtctgg atgaagagtt tgaggacctt cgaccctcct gctcggagga      300

cccggaggag aagccccagt gtttctatgg ttcatctccc caccatctcg aggacccctc      360

cctctccgag cttgagaatt tttcttccga aataatcagc ttcaagtcca tggaggacct      420

cgtaaatgaa tttgatgaga agctcaatgt ctgctttcgg aactacaacg ccaagaccga      480

gaacctagct cccgtgaaga accagttaca gatccaagag gaggaggaga cccttcagga      540

cgaggagtaa gaagtcttaa ttgccctctc ctgcttcagt cgagagccct gtagtccttg      600

tctccttgac atagtgctgg tttctgtcta taggtttatg ggctattact ttcattttcg      660

tgttgccagc ggagcagtgc cctggtactt gctgtcatag ctctatatat gtccctttac      720

agtcccctga ggagaacttt cttaaattga aaccttagag gaatgaaggt tttcctagat      780

acaaaatgga atttcaggag cacagtaaat ttcagggtct gtctatctta agctttcttt      840

atatcagtgg aaatccagcg agatattaga aataaaggcc agaaaaaatt aattaaccat      900

gatggatgaa tctatgttat tggactaatt tgcttcaaga aacaccagaa ttttgaaaat      960

cccgaatttt tgacagcccc tcaggcctgg agagttatct acagatgtta ggatatgtcc     1020

acataagaaa gcatctaaac tgaactgaga gcacagcggg ctaccctgga caaagtaaag     1080

gtggaaacta ggtgatgtgg cctttgagta tgcagattcc ttgtatcact tgctcgctac     1140

tttctagggt cttaatagta gtcaagaaaa gggatctgag aaaagtactc tttcaggagg     1200

gactagaaag agaagggggt gatatgttac acaaattaaa gaaggatgtc ttaggcattt     1260

agtaaaaatt cagtggttcc ccgctatcct cgggggatgt gtttttttgt tttgttttgt     1320

tttgtttttt tttgagatga agtttcattc tatcgcccag gctggagtgc aatggcacaa     1380

ttttggctca ctgcaacctc cacctcccag gttcaagcta ttctcctgcc tcagcctcct     1440

gagtagctgg gactacaggt gtgcgccacc atgcccgact aatttttgta ttttgagtag     1500

agatgggagt ttcaccatgt tggccaggct ggtctcgaac tcctgacctg gtgatttgcc     1560

cgccttggcc tcccaaagtg ctgggattac aggcgtgagt caccacacct ggcccatggt     1620

gggggatatg ttttaagacc cccagttaat gcctgaaacc gctgctagta ccaaacccta     1680

atgttttttc ctgtatgtac gtacatatga taaagttcag tttataagtt aggcacagta     1740

agagactaac aacagctcac agcaaaatag agcaattata acaatatatt gtaataaaaa     1800

ttatgtgaat gtgaaaaaaa aaaaaaaaaa aaaaaa                               1836


<210>  1132
<211>  2095
<212>  DNA
<213>  homo sapiens

<400>  1132
cttttaaagt ttgaggggcg gtggtggcgg cggccggcag gcgcggggga acacaggggc       60

cgctacggga gccgcgccgc cgcccatgtc attccacttc aagtgacttc atgtgatgtc      120

agctgaatgt aaaagacagt gatctcacgc ggaggggaag atgtttgcca tcaaaatgtg      180

acagaagaga cacgctgcat ggctcggaac gcatctcctt ggtggtgggg gaaagagact      240

tagaggagag aggctgcgcc ctggcccagc ctggctcggc tcagctccgc gcgccatggc      300

aagctcggct tccctggaga ccatggtgcc cccggcctgc ccgcgcgccg gagcgtcgcc      360

ggccacttcc aagacactgg ccttttccat cgagcgcatc atggccaaga cgtcggagcc      420

ccgtgcgccc tttgagcccc ggcctggagc gctagaggcg gacggcagcc agggcaagaa      480

actgctcaac ctctgctcgc cgctgccctg tatgatcccc ctccagcccc taggctacga      540

ggtgccgtca aagacactgc tcagttactc ggagctctgg aaaagcagcc tccgggcggg      600

cggcggcgga ggcggcggcg gcggtggcgg cggcggcggc gggggggccc cagtgtgcgg      660

cgccagcggc ttgtgcaaaa ccaactgtgg cgtgtgctgc aaggccgagc tgggcctggc      720

gccgtccgcg ctgcccgcgg gcagggtcat caagccgcag gtcatcaacc aggctgtggg      780

gctgccggcc agcggctcgc tctactactt caactacctg gactcgaccg cgtacccgcc      840

gtctgagctc ctcagcggcc acctcttccc gtctggcctc ctcaatgcgc aggcccccgc      900

cgccctggct gctcacccca agctctttct gctggagaac gccaagctgg ccggcctggc      960

tgcggacaag ttcccccacc cggctcccta tccccataag gagcgcttgc cggcgccgct     1020

ggagcaggta ctgaaggaaa actcggccct gactgccgag cgcggaggcg tcaagggcca     1080

cagcaagctg ccaggaggct ccgcagatgg caagcccaaa aacttcacct gcgaggtgtg     1140

cggcaaggtg tttaacgctc actataatct cacccgccac atgccggtcc acaccggagc     1200

cagaccgttc gtgtgcaaag tctgcggcaa aggctttcgc caggccagca cgctctgcag     1260

gcacaaaatt atccacaccc aggaaaagcc acataaatgc aaccagtgcg gcaaagcgtt     1320

caaccgcagc tccacgctca acacgcatat ccgcatccac gcgggctaca agcccttcgt     1380

ctgcgaattt tgcggcaaag gctttcacca aaaagggaac tacaagaacc acaagctgac     1440

ccacagcggc gagaagcagt acaaatgtac catctgcaac aaggccttcc accaggtcta     1500

caacctaacc ttccatatgc acacccacaa cgacaagaag cctttcacgt gcgccacttg     1560

cggcaaaggg ttttgcagaa actttgactt aaagaaacat gtgcgcaaac tccacgacag     1620

cgtgggccct gctgccccct ccgcaaagga cctgactagg acagtgcaga gctgagagct     1680

actgccttgc ccttccttcc ctccctgtac cacctgaaaa cagatcacac atataaactt     1740

atttctaaaa ttaaaagaaa aaaaaactat agcagagagg ctaaaatcta tttatcgaaa     1800

ccagcatatt tttggaaagc taaatgtttc ctcgatgact ggcagcaaac tcgtggcccc     1860

cacctttgta tattcaggaa acttatttaa atccagtgcg ccgaaacgta tttaattcca     1920

ggcctccgct tctcctgggg cagccagttt taaccccagc ctgtcaccgt gagcgcccca     1980

gaagagcgcg gcgcccctag ccatctttat acagccatgt aaatcctcct gtacaagcga     2040

acacggaata tatacatata taactcaata aacagaatca ttagtgaaaa aaaaa          2095


<210>  1133
<211>  3713
<212>  DNA
<213>  homo sapiens

<400>  1133
attcccatgg cccgggctca ggcgtccaac ctgctgccgc ctgggccccg ccgagcggag       60

ctagcgccgc gcgcagagca cacgctcgcg ctccagctcc cctcctgcgc ggttcatgac      120

tgtgtcccct gaccgcagcc tctgcgagcc cccgccgcag gaccacggcc cgctccccgc      180

cgccgcgagg gccccgagcg aaggaaggaa gggaggcgcg ctgtgcgccc cgcggagccc      240

gcgaaccccg ctcgctgccg gctgcccagc ctggctggca ccatgctgcc cgcgcgctgc      300

gcccgcctgc tcacgcccca cttgctgctg gtgttggtgc agctgtcccc tgctcgcggc      360

caccgcacca caggccccag gtttctaata agtgaccgtg acccacagtg caacctccac      420

tgctccagga ctcaacccaa acccatctgt gcctctgatg gcaggtccta cgagtccatg      480

tgtgagtacc agcgagccaa gtgccgagac ccgaccctgg gcgtggtgca tcgaggtaga      540

tgcaaagatg ctggccagag caagtgtcgc ctggagcggg ctcaagccct ggagcaagcc      600

aagaagcctc aggaagctgt gtttgtccca gagtgtggcg aggatggctc ctttacccag      660

gtgcagtgcc atacttacac tgggtactgc tggtgtgtca ccccggatgg gaagcccatc      720

agtggctctt ctgtgcagaa taaaactcct gtatgttcag gttcagtcac cgacaagccc      780

ttgagccagg gtaactcagg aaggaaagat gacgggtcta agccgacacc cacgatggag      840

acccagccgg tgttcgatgg agatgaaatc acagccccaa ctctatggat taaacacttg      900

gtgatcaagg actccaaact gaacaacacc aacataagaa attcagagaa agtctattcg      960

tgtgaccagg agaggcagag tgccctggaa gaggcccagc agaatccccg tgagggtatt     1020

gtcatccctg aatgtgcccc tgggggactc tataagccag tgcaatgcca ccagtccact     1080

ggctactgct ggtgtgtgct ggtggacaca gggcgcccgc tgcctgggac ctccacacgc     1140

tacgtgatgc ccagttgtga gagcgacgcc agggccaaga ctacagaggc ggatgacccc     1200

ttcaaggaca gggagctacc aggctgtcca gaagggaaga aaatggagtt tatcaccagc     1260

ctactggatg ctctcaccac tgacatggtt caggccatta actcagcagc gcccactgga     1320

ggtgggaggt tctcagagcc agaccccagc cacaccctgg aggagcgggt agtgcactgg     1380

tatttcagcc agctggacag caatagcagc aacgacatta acaagcggga gatgaagccc     1440

ttcaagcgct acgtgaagaa gaaagccaag cccaagaaat gtgcccggcg tttcaccgac     1500

tactgtgacc tgaacaaaga caaggtcatt tcactgcctg agctgaaggg ctgcctgggt     1560

gttagcaaag aaggacgcct cgtctaagga gcagaaaacc caagggcagg tggagagtcc     1620

agggaggcag gatggatcac cagacaccta accttcagcg ttgcccatgg ccctgccaca     1680

tcccgtgtaa cataagtggt gcccaccatg tttgcacttt taataactct tacttgcgtg     1740

ttttgttttt ggtttcattt taaaacacca atatctaata ccacagtggg aaaaggaaag     1800

ggaagaaaga ctttattctc tctcttattg taagtttttg gatctgctac tgacaacttt     1860

tagagggttt tgggggggtg ggggagggtg ttgttggggc tgagaagaaa gagatttata     1920

tgctgtatat aaatatatat gtaaattgta tagttctttt gtacaggcat tggcattgct     1980

gtttgtttat ttctctccct ctgcctgctg tgggtggtgg gcactctgga cacatagtcc     2040

agctttctaa aatccaggac tctatcctgg gcctactaaa cttctgtttg gagactgacc     2100

cttgtgtata aagacgggag tcctgcaatt gtactgcgga ctccacgagt tcttttctgg     2160

tgggaggact atattgcccc atgccattag ttgtcaaaat tgataagtca cttggctctc     2220

ggccttgtcc agggaggttg ggctaaggag agatggaaac tgccctggga gaggaaggga     2280

gtccagatcc catgaatagc ccacacaggt accggctctc agagggtccg tgcattcctg     2340

ctctccggac ccccaaaggg cccagcattg gtgggtgcac cagtatctta gtgaccctcg     2400

gagcaaatta tccacaaagg atttgcatta cgtcactcga aacgttttca tccatgctta     2460

gcatctactc tgtataacgc atgagagggg aggcaaagaa gaaaaagaca cacagaaggg     2520

cctttaaaaa agtagatatt taatatctaa gcaggggagg ggacaggaca gaaagcctgc     2580

actgaggggt gcggtgccaa cagggaaact cttcacctcc ctgcaaacct accagtgagg     2640

ctcccagaga cgcagctgtc tcagtgccag gggcagattg ggtgtgacct ctccactcct     2700

ccatctcctg ctgttgtcct agtggctatc acaggcctgg gtgggtgggt tgggggaggt     2760

gtcagtcacc ttgttggtaa cactaaagtt gttttgttgg ttttttaaaa acccaatact     2820

gaggttcttc ctgttccctc aagttttctt atgggcttcc aggctttaag ctaattccag     2880

aagtaaaact gatcttgggt ttcctattct gcctccccta gaagggcagg ggtgataacc     2940

cagctacagg gaaatcccgg cccagctttc cacaggcatc acaggcatct tccgcggatt     3000

ctagggtggg ctgcccagcc ttctggtctg aggcgcagct ccctctgccc aggtgctgtg     3060

cctattcaag tggccttcag gcagagcagc aagtggccct tagcgcccct tcccataagc     3120

agctgtggtg gcagtgaggg aggttgggta gccctggact ggtcccctcc tcagatcacc     3180

cttgcaaatc tggcctcatc ttgtattcca acccgacatc cctaaaagta cctccacccg     3240

ttccgggtct ggaaggcgtt ggcaccacaa gcactgtccc tgtgggagga gcacaacctt     3300

ctcgggacag gatctgatgg ggtcttgggc taaaggaggt ccctgctgtc ctggagaaag     3360

tcctagaggt tatctcagga atgactggtg gccctgcccc aacgtggaaa ggtgggaagg     3420

aagccttctc ccattagccc caatgagaga actcaacgtg ccggagctga gtgggccttg     3480

cacgagacac tggccccact ttcaggcctg gaggaagcat gcacacatgg agacggcgcc     3540

tgcctgtaga tgtttggatc ttcgagatct ccccaggcat cttgtctccc acaggatcgt     3600

gtgtgtaggt ggtgttgtgt ggttttcctt tgtgaaggag agagggaaac tatttgtagc     3660

ttgttttata aaaaataaaa aatgggtaaa tcttgaaaaa aaaaaaaaaa aaa            3713


<210>  1134
<211>  2417
<212>  DNA
<213>  homo sapiens

<400>  1134
atgcgctgag cttcggttgg cccggcttcc ttgaggcgta agctcggtct gtccaatgag       60

gagcgagcgt cgcgggggcc gtcgggaagg gcggccgacc catataagca gcctgcgggg      120

cgttccctcg ggttgtggtt ggtgtgcggg tttcggttgg aggactcgtt ggggaggtgg      180

cctgcgcttg tagagactgc atccccgaga cgatggcgga gggagataat cgcagcacca      240

acctgctggc tgcagagact gcaagtctgg aagaacagct gcaaggatgg ggagaagtga      300

tgctgatggc tgataaagtc ctccgatggg aaagagcctg gtttccacct gccatcatgg      360

gtgtggtttc tttggtgttt ctgattatct actatctaga tccatctgtt ctgtccggcg      420

tttcctgttt tgttatgttt ttgtgcttgg ctgactacct tgttcccatt ctagcgccta      480

gaatttttgg ctccaataaa tggaccactg aacaacagca aagattccat gaaatttgca      540

gcaatctagt aaaaactcga cgcagagctg tgggttggtg gaaacgcctc ttcacactaa      600

aggaagaaaa acctaagatg tacttcatga ccatgatcgt ttcccttgct gcggttgctt      660

gggtgggaca acaagtccac aacctgcttc tcacctacct gatagtgact tccttactat      720

tgcttcctgg actaaaccaa catggaatca ttttgaagta cattggaatg gccaagaggg      780

agataaacaa acttctcaaa caaaaagaaa agaaaaacga atgattcatc tgctttaatc      840

agtgtgatta atgcagcacc cattgccccg ggaaccgttt ctgctgtact atctggatac      900

taaaatgtta cggaagtagc tctttgttct ccctcactct gcccttagtt aatagaaatt      960

cagactcgcc aagtaaggct tcgtgcatag tgtcttcatg tcgcgtatag ttgagcgcgt     1020

tcttagcagt tggcttcatg gacaactcat tagtgttttg acttttctta cccagcgtta     1080

attgaattct tgcttttaga caacttcctt tttgtagtgg tgaaccttgc cctttagtac     1140

agttcaagtg aatctggata attgttcatc tttgctttag cttagatacc atgtagtggt     1200

ctgtggctac aggaagctgg ttctgtctgc ttccacagtc tgcttaaaaa actgtctgac     1260

ttcgtgaata tagagaccaa gtttaccact tctgatgaag agaccaatta agattcattc     1320

ctcattctgt ttctttccag tgggagaaga gtccccatga aataagatga aactgattcc     1380

atgcactagt acatgtaggc ttctcccttg tgcaaagctt agcaatttgt aggaaacttt     1440

gatctttttg tccaagaaaa ggaatgtctg acaggcttaa gctttcgtcc ccttgcactt     1500

agactcgaag ttagtaaatc cttaaaggct ttttaatagc agacttccaa aagattgcat     1560

ttaggatttc tagcatgctt ttaatttcag attttcagct gacattagct atagtataca     1620

gtaggttaag actcatgtct atgactttca ctctaagact ggcaaaagga cagcagtctt     1680

ctatgtttag tcaatattca tttcagtaga agataatctt atctaatttt tgagaccaga     1740

ataagccttt taaggtaaac ctcaaaatta tcattttatg gtaatactga ccattttagt     1800

cccctaggtt tgacatggga gatagtgact acactggtgt ctgacttttt tcctagagat     1860

ttctccctga aaaatacaag ggctgttggt gagagcagac ttgaggtgat gatagttggc     1920

ctctggtcta caaagatttc ataactcctt ggaaagcttc ttataatcat tcttaacttc     1980

ttggtagcta gaaatttaga gtagttgaaa tctttaggaa tgaacttctg agggccaaaa     2040

aatgtgactg acgggaacaa ttcttaaact gattaactag ctgtaatata gttttgtgaa     2100

tttattgcac tgatgttgta ccttgtggta tatctgtccc tattaaataa gtgttgtttt     2160

ctcctcttta atattgctgt gaacagtggt gcccattgta gcatatgttt gatttttttt     2220

tattatttca taagaaaact acgttaattt taccttactt tcattgtaaa taagcctgtc     2280

ttcctatctg gattttttgt gtgcatacat attctactga ttaactactt ttgcagtttt     2340

aatcctgtat tatttcttct actttgtttt gtgtaaaagg ggaaaaaata aaaaaagctg     2400

gaatcttcaa aaaaaaa                                                    2417


<210>  1135
<211>  7291
<212>  DNA
<213>  homo sapiens

<400>  1135
acacagtact ctcagcttgt tggtggaagc ccctcatctg ccttcattct gaaggcaggg       60

cccggcagag gaaggatcag agggtcgcgg ccggagggtc ccggccggtg gggccaactc      120

agagggagag gaaagggcta gagacacgaa gaacgcaaac catcaaattt agaagaaaaa      180

gccctttgac tttttccccc tctccctccc caatggctgt gtagcaaaca tccctggcga      240

taccttggaa aggacgaagt tggtctgcag tcgcaatttc gtgggttgag ttcacagttg      300

tgagtgcggg gctcggagat ggagccgtgg tcctctaggt ggaaaacgaa acggtggctc      360

tgggatttca ccgtaacaac cctcgcattg accttcctct tccaagctag agaggtcaga      420

ggagctgctc cagttgatgt actaaaagca ctagattttc acaattctcc agagggaata      480

tcaaaaacaa cgggattttg cacaaacaga aagaattcta aaggctcaga tactgcttac      540

agagtttcaa agcaagcaca actcagtgcc ccaacaaaac agttatttcc aggtggaact      600

ttcccagaag acttttcaat actatttaca gtaaaaccaa aaaaaggaat tcagtctttc      660

cttttatcta tatataatga gcatggtatt cagcaaattg gtgttgaggt tgggagatca      720

cctgtttttc tgtttgaaga ccacactgga aaacctgccc cagaagacta tcccctcttc      780

agaactgtta acatcgctga cgggaagtgg catcgggtag caatcagcgt ggagaagaaa      840

actgtgacaa tgattgttga ttgtaagaag aaaaccacga aaccacttga tagaagtgag      900

agagcaattg ttgataccaa tggaatcacg gtttttggaa caaggatttt ggatgaagaa      960

gtttttgagg gggacattca gcagtttttg atcacaggtg atcccaaggc agcatatgac     1020

tactgtgagc attatagtcc agactgtgac tcttcagcac ccaaggctgc tcaagctcag     1080

gaacctcaga tagatgagta tgcaccagag gatataatcg aatatgacta tgagtatggg     1140

gaagcagagt ataaagaggc tgaaagtgta acagagggac ccactgtaac tgaggagaca     1200

atagcacaga cggaggcaaa catcgttgat gattttcaag aatacaacta tggaacaatg     1260

gaaagttacc agacagaagc tcctaggcat gtttctggga caaatgagcc aaatccagtt     1320

gaagaaatat ttactgaaga atatctaacg ggagaggatt atgattccca gaggaaaaat     1380

tctgaggata cactatatga aaacaaagaa atagacggca gggattctga tcttctggta     1440

gatggagatt taggcgaata tgatttttat gaatataaag aatatgaaga taaaccaaca     1500

agccccccta atgaagaatt tggtccaggt gtaccagcag aaactgatat tacagaaaca     1560

agcataaatg gccatggtgc atatggagag aaaggacaga aaggagaacc agcagtggtt     1620

gagcctggta tgcttgtcga aggaccacca ggaccagcag gacctgcagg tattatgggt     1680

cctccaggtc tacaaggccc cactggaccc cctggtgacc ctggcgatag gggcccccca     1740

ggacgtcctg gcttaccagg ggctgatggt ctacctggtc ctcctggtac tatgttgatg     1800

ttaccgttcc gttatggtgg tgatggttcc aaaggaccaa ccatctctgc tcaggaagct     1860

caggctcaag ctattcttca gcaggctcgg attgctctga gaggcccacc tggcccaatg     1920

ggtctaactg gaagaccagg tcctgtgggg gggcctggtt catctggggc caaaggtgag     1980

agtggtgatc caggtcctca gggccctcga ggcgtccagg gtccccctgg tccaacggga     2040

aaacctggaa aaaggggtcg tccaggtgca gatggaggaa gaggaatgcc aggagaacct     2100

ggggcaaagg gagatcgagg gtttgatgga cttccgggtc tgccaggtga caaaggtcac     2160

aggggtgaac gaggtcctca aggtcctcca ggtcctcctg gtgatgatgg aatgagggga     2220

gaagatggag aaattggacc aagaggtctt ccaggtgaag ctggcccacg aggtttgctg     2280

ggtccaaggg gaactccagg agctccaggg cagcctggta tggcaggtgt agatggcccc     2340

ccaggaccaa aagggaacat gggtccccaa ggggagcctg ggcctccagg tcaacaaggg     2400

aatccaggac ctcagggtct tcctggtcca caaggtccaa ttggtcctcc tggtgaaaaa     2460

ggaccacaag gaaaaccagg acttgctgga cttcctggtg ctgatgggcc tcctggtcat     2520

cctgggaaag aaggccagtc tggagaaaag ggggctctgg gtccccctgg tccacaaggt     2580

cctattggat acccgggccc ccggggagta aagggagcag atggtgtcag aggtctcaag     2640

ggatctaaag gtgaaaaggg tgaagatggt tttccaggat tcaaaggtga catgggtcta     2700

aaaggtgaca gaggagaagt tggtcaaatt ggcccaagag gggaagatgg ccctgaagga     2760

cccaaaggtc gagcaggccc aactggagac ccaggtcctt caggtcaagc aggagaaaag     2820

ggaaaacttg gagttccagg attaccagga tatccaggaa gacaaggtcc aaagggttcc     2880

actggattcc ctgggtttcc aggtgccaat ggagagaaag gtgcacgggg agtagctggc     2940

aaaccaggcc ctcggggtca gcgtggtcca acgggtcctc gaggttcaag aggtgcaaga     3000

ggtcccactg ggaaacctgg gccaaagggc acttcaggtg gcgatggccc tcctggccct     3060

ccaggtgaaa gaggtcctca aggacctcag ggtccagttg gattccctgg accaaaaggc     3120

cctcctggac cacctgggaa ggatgggctg ccaggacacc ctgggcaacg tggggagact     3180

ggatttcaag gcaagaccgg ccctcctggg ccagggggag tggttggacc acagggacca     3240

accggtgaga ctggtccaat aggggaacgt gggcatcctg gccctcctgg ccctcctggt     3300

gagcaaggtc ttcctggtgc tgcaggaaaa gaaggtgcaa agggtgatcc aggtcctcaa     3360

ggtatctcag ggaaagatgg accagcagga ttacgtggtt tcccagggga aagaggtctt     3420

cctggagctc agggtgcacc tggactgaaa ggaggggaag gtccccaggg cccaccaggt     3480

ccagttggct caccaggaga acgtgggtca gcaggtacag ctggcccaat tggtttacca     3540

gggcgcccgg gacctcaggg tcctcctggt ccagctggag agaaaggtgc tcctggagaa     3600

aaaggtcccc aagggcctgc agggagagat ggagttcaag gtcctgttgg tctcccaggg     3660

ccagctggtc ctgccggctc ccctggggaa gacggagaca agggtgaaat tggtgagccg     3720

ggacaaaaag gcagcaaggg tgacaaggga gaaaatggcc ctcccggtcc cccaggtctt     3780

caaggaccag ttggtgcccc tggaattgct ggaggtgatg gtgaaccagg tcctagagga     3840

cagcagggga tgtttgggca aaaaggtgat gagggtgcca gaggcttccc tggacctcct     3900

ggtccaatag gtcttcaggg tctgccaggc ccacctggtg aaaaaggtga aaatggggat     3960

gttggtccca tggggccacc tggtcctcca ggcccaagag gccctcaagg tcccaatgga     4020

gctgatggac cacaaggacc cccagggtct gttggttcag ttggtggtgt tggagaaaag     4080

ggtgaacctg gagaagcagg gaacccaggg cctcctgggg aagcaggtgt aggcggtccc     4140

aaaggagaaa gaggagagaa aggggaagct ggtccacctg gagctgctgg acctccaggt     4200

gccaaggggc caccaggtga tgatggccct aagggtaacc cgggtcctgt tggttttcct     4260

ggagatcctg gtcctcctgg ggaacctggc cctgcaggtc aagatggtgt tggtggtgac     4320

aagggtgaag atggagatcc tggtcaaccg ggtcctcctg gcccatctgg tgaggctggc     4380

ccaccaggtc ctcctggaaa acgaggtcct cctggagctg caggtgcaga gggaagacaa     4440

ggtgaaaaag gtgctaaggg ggaagcaggt gcagaaggtc ctcctggaaa aaccggccca     4500

gtcggtcctc agggacctgc aggaaagcct ggtccagaag gtcttcgggg catccctggt     4560

cctgtgggag aacaaggtct ccctggagct gcaggccaag atggaccacc tggtcctatg     4620

ggacctcctg gcttacctgg tctcaaaggt gaccctggct ccaagggtga aaagggacat     4680

cctggtttaa ttggcctgat tggtcctcca ggagaacaag gggaaaaagg tgaccgaggg     4740

ctccctggaa ctcaaggatc tccaggagca aaaggggatg ggggaattcc tggtcctgct     4800

ggtcccttag gtccacctgg tcctccaggt ttaccaggtc ctcaaggccc aaagggtaac     4860

aaaggctcta ctggacccgc tggccagaaa ggtgacagtg gtcttccagg gcctcctggg     4920

tctccaggtc cacctggtga agtcattcag cctttaccaa tcttgtcctc caaaaaaacg     4980

agaagacata ctgaaggcat gcaagcagat gcagatgata atattcttga ttactcggat     5040

ggaatggaag aaatatttgg ttccctcaat tccctgaaac aagacattga gcatatgaaa     5100

tttccaatgg gtactcagac caatccagcc cgaacttgta aagacctgca actcagccat     5160

cctgacttcc cagatggtga atattggatt gatcctaacc aaggttgctc aggagattcc     5220

ttcaaagttt actgtaattt cacatctggt ggtgagactt gcatttatcc agacaaaaaa     5280

tctgagggag taagaatttc atcatggcca aaggagaaac caggaagttg gtttagtgaa     5340

tttaagaggg gaaaactgct ttcatactta gatgttgaag gaaattccat caatatggtg     5400

caaatgacat tcctgaaact tctgactgcc tctgctcggc aaaatttcac ctaccactgt     5460

catcagtcag cagcctggta tgatgtgtca tcaggaagtt atgacaaagc acttcgcttc     5520

ctgggatcaa atgatgagga gatgtcctat gacaataatc cttttatcaa aacactgtat     5580

gatggttgtg cgtccagaaa aggctatgaa aagactgtca ttgaaatcaa tacaccaaaa     5640

attgatcaag tacctattgt tgatgtcatg atcaatgact ttggtgatca gaatcagaag     5700

ttcggatttg aagttggtcc tgtttgtttt cttggctaag attaagacaa agaacatatc     5760

aaatcaacag aaaatatacc ttggtgccac caacccattt tgtgccacat gcaagttttg     5820

aataaggatg gtatagaaaa caacgctgca tatacaggta ccatttagga aataccgatg     5880

cctttgtggg ggcagaatca catggcaaaa gctttgaaaa tcataaagat ataagttggt     5940

gtggctaaga tggaaacagg gctgattctt gattcccaat tctcaactct ccttttccta     6000

tttgaatttc tttggtgctg tagaaaacaa aaaaagaaaa atatatattc ataaaaaata     6060

tggtgctcat tctcatccat ccaggatgta ctaaaacagt gtgtttaata aattgtaatt     6120

attttgtgta cagttctata ctgttatctg tgtccatttc caaaacttgc acgtgtccct     6180

gaattccatc tgactctaat tttatgagaa ttgcagaact ctgatggcaa taaatatatg     6240

tattatgaaa aaataaagtt gtaatttctg atgactctaa gtccctttct ttggttaata     6300

ataaaatgcc tttgtatata ttgatgttga agagttcaat tatttgatgt cgccaacaaa     6360

attctcagag ggcaaaaatc tggaagactt ttggaagcac actctgatca actcttctct     6420

gccgacagtc attttgctga atttcagcca aaaatattat gcattttgat gctttattca     6480

aggctatacc tcaaactttt tcttctcaga atccaggatt tcacaggata cttgtatata     6540

tggaaaacaa gcaagtttat atttttggac agggaaatgt gtgtaagaaa gtatattaac     6600

aaatcaatgc ctccgtcaag caaacaatca tatgtatact ttttttctac gttatctcat     6660

ctccttgttt tcagtgtgct tcaataatgc aggttaatat taaagatgga aattaagcaa     6720

ttatttatga atttgtgcaa tgttagattt tcttatcaat caagttcttg aatttgattc     6780

taagttgcat attataacag tctcgaaaat tattttactt gcccaacaaa tattactttt     6840

ttcctttcaa gataatttta taaatcattt gacctaccta attgctaaat gaataacata     6900

tggtggactg ttattaagag tatttgtttt aagtcattca ggaaaatcta aacttttttt     6960

tccactaagg tatttacttt aaggtagctt gaaatagcaa tacaatttaa aaattaaaaa     7020

ctgaattttg tatctatttt aagtaatata tgtaagactt gaaaataaat gttttatttc     7080

ttatataaag tgttaaatta attgatacca gatttcactg gaacagtttc aactgataat     7140

ttatgacaaa agaacatacc tgtaatattg aaattaaaaa gtgaaatttg tcataaagaa     7200

tttcttttat ttttgaaatc gagtttgtaa atgtcctttt aagaagggag atatgaatcc     7260

aataaataaa ctcaagtctt ggctacctgg a                                    7291


<210>  1136
<211>  5054
<212>  DNA
<213>  homo sapiens

<400>  1136
gtgcgcccct ccgaacgtcc ccgggagccc agccagagcg agcgccgggg ccgggcgcgc       60

aggagtgaaa aggaggcggc ggccgcagct gcgagcaaca gatccggacg ccgcgagctg      120

acccgctctg ctgttgggcg attttttttt aattgcagaa aaatttatta aattggaaaa      180

tcttgcgttt ttcaatggcg ctggccccgg gtcagcgggc gattttctct gcatcaagat      240

gggctttgcc gtttccgtag tgggcaccag tggtggcctg attgtcagtc ttctcccggc      300

atttttaagg ccaggagccg agcgctgctt gtaggcgaat accctacaga gcggtttggc      360

tttttaaatt actgttatta ttttgggcag agaacagtcg gtctggtgca ccccgtcctc      420

gctgcagaag aggctgcgag tccgaggtgg gtctctcgga aggtgaaatt ccttctgggg      480

tgagcgagcc ccggccccgc gcgcagtcca gcggccccgc gtgtgtgccc tcgccctgcc      540

ggagccggga aaatggaggc tgtgattgag aaggaatgca gcgcgctcgg aggcctcttc      600

cagaccatca tcagcgacat gaaggggagc tatccagttt gggaagattt cataaacaaa      660

gcaggaaagc tgcagtccca gcttcggaca acagtagtag cagcagctgc cttcttggac      720

gcctttcaga aagtggctga catggccacc aacacacgtg gtgggaccag ggagattgga      780

tctgctctca ccaggatgtg catgaggcac agaagcattg aagccaagct gaggcagttt      840

tcgagcgctt taattgattg tctgataaac ccacttcaag aacagatgga agaatggaag      900

aaagtggcca accagctgga taaagaccac gcaaaagaat ataagaaagc ccgccaagag      960

ataaaaaaga agtcctcgga tacgctgaaa ctgcagaaga aagcaaaaaa agggagaggt     1020

gatatccagc ctcagttgga cagtgctctc caagatgtca atgataagta tctcttattg     1080

gaagaaacag aaaagcaggc tgtccggaag gctttgattg aagaacgtgg ccgattctgt     1140

accttcatct ctatgctgcg gccagtgatt gaagaagaaa tctcaatgct aggggaaata     1200

acccaccttc agaccatctc ggaagatcta aaaagcctga ccatggaccc tcacaaactg     1260

ccctcctcaa gtgaacaggt gattctggac ttgaaaggtt ctgattacag ctggtcgtat     1320

cagacgccac cctcttcccc cagcaccacc atgtccagaa agtccagtgt ctgcagcagc     1380

ctgaacagtg tcaacagcag tgactcccgg tccagcggct cccactcgca ttcccccagc     1440

tcacattacc gctaccgcag ctccaacctg gcccagcagg ctcctgtgag gctgtccagc     1500

gtgtcctccc atgactcagg attcatatcc caggatgcct tccagtccaa gtcaccatcc     1560

cccatgccgc cagaggcccc caaccagttg tctaacgggt tttctcacta tagtttatca     1620

agtgagtccc acgtggggcc cacgggtgca ggccttttcc ctcattgcct gcctgcctcc     1680

cgcctgctcc ctcgggtcac ctctgtccac cttccagact acgctcatta ttacaccatt     1740

gggcccggca tgttcccgtc atctcagatc cctagctgga aggactgggc taagcctggg     1800

ccctatgacc agcctctggt gaacaccctg cagcgccgca aagagaagcg agaaccggac     1860

cccaacgggg gaggacccac taccgccagc ggcccacctg cagcagctga ggaggctcag     1920

agaccacgga gcatgactgt atcggctgcc accaggcctg gtgaggagat ggaggcttgt     1980

gaggagctgg ccctggccct gtctcggggc ctgcagctgg acacccagag gagcagccgg     2040

gactcgcttc agtgctccag cggctacagc acccagacaa ccaccccctg ctgctctgag     2100

gacaccatcc cttcccaagt ttcagattat gattatttct ctgtaagtgg tgaccaggag     2160

gcagatcagc aggagttcga caagtcctcc accattccaa gaaacagcga catcagccag     2220

tcctaccgac ggatgttcca agccaagcgt ccagcctcaa ctgctggcct ccccaccacc     2280

ctgggacctg ctatggtcac tccaggggtt gcaactatcc gacggacccc ttccaccaag     2340

ccttctgtcc gccggggaac cattggagct ggtcccatcc ccatcaagac acccgtgatc     2400

cctgtcaaga ccccaaccgt cccagacctc ccaggggtgt tgccagcccc tccagatggg     2460

ccagaagagc ggggggagca cagccctgag tcgccatctg tgggtgaggg cccccaaggt     2520

gtcaccagca tgccctcctc aatgtggagc ggccaagctt ccgttaaccc tccacttcca     2580

ggcccgaagc ccagtatccc tgaggagcac agacaggcaa ttccagaaag tgaagctgaa     2640

gaccaggaac gggaaccccc aagtgccact gtctccccag gccagattcc agagagtgac     2700

cctgcagacc tgagcccaag ggatactcca caaggagaag acatgctgaa cgccatccga     2760

aggggcgtga aactgaagaa gaccacgaca aacgatcgct cagcccctcg cttttcttag     2820

gttcacaaga aatgcgccgg tggggaatga actgtttcat taataaaacc taatttgtct     2880

tgatccattc cactctataa taaaacaaaa gattttgtag gcaactcgga atatagctct     2940

tttgaaagta ctcgacacct ttagataaga attaaaacca acctatgtaa ctgacataat     3000

cttgatcttt taatttgtaa atattgacaa ttttctttct gcacatttta atcttagttt     3060

cccttttgat ttttctgaag gtgccaaatt ccatttaact tttttacaag tctttgtaaa     3120

attttaaatg cataaagggg gttggggcag gggaaccacg aagtagttaa ttttagaaaa     3180

ggatttacta tacttcactc ttcttttttt ttccccacaa gcttttgtag atgcattgta     3240

gtagtctagc ttagaagcaa atgcaagtta ttttaatgta caaactaaat gggtaagagg     3300

taaaatcttc atttaaatat actatgttct ggatgaaaag agcaggagta acaattgatg     3360

agcaatattc agagtgaagt aaatctggaa atggtagact gtgttgggat tggggggagg     3420

gccatgggag gggtacatcg tcaacatagc cgatcctgtt acatttaaga gtagcctcgt     3480

aggttgaatt tcttctggta gcttcatggt aaatgcatcc gaataagcca tactggattg     3540

cagtgtttgt ttctgtaggg tgtttaagga cttgacttcc tttctcccat gattcctctg     3600

gactgcacac agcacccaca accagcccca tgcatgctgc tgcctctggg cagtcgtaga     3660

atctcccact tcagtttctc gttgattgta ctcaccttta tggaatccaa atacatccaa     3720

aagggtaagg cagttttaaa aatgtgaaaa catttaaaaa tgataatagc agggaattct     3780

tagattatag taaatgcctt ttacttaact gtgcccagca ggctgggtgc gttaaaaagc     3840

ccaagtattt tgaaaaaact cgaacagatt tgacaagggt agccagcttg gagtctagca     3900

acttgccaat gtgtttacca atctgggggc ttgtttttct tttcttcttt caaataaatg     3960

gcagttaact ggctttacag taaacattga agagaggagg atttgtttat tgtcactggg     4020

aatctgacca ctatactgtc ctttttttgt attctgggta aatgtttttt ggaaaagatt     4080

tgtcttttct aagtggaagt taaatttgtt atactgccca tcccctaaag ccaacagaga     4140

tttgtagatt taaagggatc acatttgaag acaatagtgt ttaagaaagc aagcaagtcc     4200

cttagcagtc aggtcataac agggcacatt tctgaccgaa ccctctcaag gcagaggagg     4260

agtttggtgg gtttcataca ccctgcagat tcctgttggc tctaaccctc aattacctaa     4320

tcttatgctt taacacataa ctgcattgga tgtgagagta acgtaccgta tggtcattgt     4380

tctatatatt aacattgaac actgctgcga ttgctcaagg acattttatg ttacggcttt     4440

aaagcaaagg catgattatt agaaactatt taagcttttt tctttgaaaa acaagctcct     4500

tttacagaat ataaacaaca gtagtgcctg tggtttagcc caccaatctt gatgactaaa     4560

agtagctgat gcattgtgca tatgatgctt gagatggttt ttgcaaaagc agaaatcgct     4620

gcaaggtaat cacaatagat aaaagtggta ttttaaacct ttgaaataaa tggatgtaac     4680

tgtaccttgg tacagctttt cacttgttta gtttttaaac gttagtataa tctgaataaa     4740

taaaatgttg ccaaattcaa tgtagaaaga atgtgacaac acaccttggg tagttctgct     4800

tgtgtttttg catattgtaa aagcagtgtc acagctaaaa agaaagaaat cgtttctaac     4860

agtaaattat tgtgctttag ttgctagttt gtactgagag ttgacctctc cctgtgcagt     4920

tttttgttct aaacttgtat aaataacaat tgtgtaatgt gtctccctcc tacattgtaa     4980

caattgcttc agcctacgtt ataaataaag aaccactaga ttaaaaaagt cctgtatttc     5040

aaaaaaaaaa aaaa                                                       5054


<210>  1137
<211>  3379
<212>  DNA
<213>  homo sapiens

<400>  1137
attccagatg cctgggccga ctcgaagccc ttataaggcg cggagacacc ggctctggct       60

gggccgcccg cctccacagc cgccgcccag ggttctcccg ccactgccgc ccgcaccccc      120

gcccccgcgg ggttaagatc acacacgcgc ccacgccggc ccgcggggcg tgcactttcg      180

ctgggttccg tccgccgcag cccaaacagt taactgaacg gggaggggag ggggcggggc      240

ttacccgggg tcaccgccag ggccctgctg ggttccacgc cacgttcctg tctccgcagg      300

gcgttcgatc cctagaggga ggagcctgtc caaacggacg ctaacggcct acctccccct      360

caggtgctct tacagcctgt tccaagtgtg gcttaatccg tctccaccac cagatctttc      420

tccgtggatt cctctgctaa gaccgctgcc atgccagtga cggtaacccg caccaccatc      480

acaaccacca cgacgtcatc ttcgggcctg gggtccccca tgatcgtggg gtcccctcgg      540

gccctgacac agcccctggg tctccttcgc ctgctgcagc tggtgtctac ctgcgtggcc      600

ttctcgctgg tggctagcgt gggcgcctgg acggggtcca tgggcaactg gtccatgttc      660

acctggtgct tctgcttctc cgtgaccctg atcatcctca tcgtggagct gtgcgggctc      720

caggcccgct tccccctgtc ttggcgcaac ttccccatca ccttcgcctg ctatgcggcc      780

ctcttctgcc tctcggcctc catcatctac cccaccacct atgtccagtt cctgtcccac      840

ggccgttcgc gggaccacgc catcgccgcc accttcttct cctgcatcgc gtgtgtggct      900

tacgccaccg aagtggcctg gacccgggcc cggcccggcg agatcactgg ctatatggcc      960

accgtacccg ggctgctgaa ggtgctggag accttcgttg cctgcatcat cttcgcgttc     1020

atcagcgacc ccaacctgta ccagcaccag ccggccctgg agtggtgcgt ggcggtgtac     1080

gccatctgct tcatcctagc ggccatcgcc atcctgctga acctggggga gtgcaccaac     1140

gtgctaccca tccccttccc cagcttcctg tcggggctgg ccttgctgtc tgtcctcctc     1200

tatgccaccg cccttgttct ctggcccctc taccagttcg atgagaagta tggcggccag     1260

cctcggcgct cgagagatgt aagctgcagc cgcagccatg cctactacgt gtgtgcctgg     1320

gaccgccgac tggctgtggc catcctgacg gccatcaacc tactggcgta tgtggctgac     1380

ctggtgcact ctgcccacct ggtttttgtc aaggtctaag actctcccaa gaggctcccg     1440

ttccctctcc aacctctttg ttcttcttgc ccgagttttc tttatggagt acttctttcc     1500

tccgcctttc ctctgttttc ctcttcctgt ctcccctccc tcccaccttt ttctttcctt     1560

cccaattcct tgcactctaa ccagttcttg gatgcatctt cttccttccc tttcctcttg     1620

ctgtttcctt cctgtgttgt tttgttgccc acatcctgtt ttcacccctg agctgtttct     1680

ctttttcttt tctttttttt tttttttttt ttttaagacg gattctcact ctgtggccca     1740

ggctggagtg cagtggtgcg atctcgactc actgcaaccc ccgcctcctg ggttcaagcg     1800

attctcctgc cccagcctcc caagtagctg ggaggacagg tgtgagctgc cgcacccagc     1860

ctgtttctct ttttccactc ttcttttttc tcatctcttt tctgggttgc ctgtcggctt     1920

tcttatctgc ctgttttgca agcaccttct cctgtgtcct tgggagccct gagacttctt     1980

tctctccttg cctccaccca cctccaaagg tgctgagctc acatccacac cccttgcagc     2040

cgtccatgcc acagcccccc aaggggcccc attgccaaag catgcctgcc caccctcgct     2100

gtgccttagt cagtgtgtac gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtttgggggg     2160

tggggggtgg gtagctgggg attgggccct ctttctccca gtggaggaag gtgtgcagtg     2220

tacttcccct ttaaattaaa aaacatatat atatatatat ttggaggtca gtaatttcca     2280

atgggcggga ggctttaagc accgaccctg ggtccctagg ccccgcctgg cactcagcct     2340

tgccagagat tggctccaga atttttgcca ggcttacaga acacccactg cctagaggcc     2400

atcttaaagg aagcaggggc tggatgcctt tcatcccaac tattctctgt ggtatcaaaa     2460

agaaaaaaaa aaaaaaagaa ggagtcgggg ccgggcgtgg tggctcacgc ctgtaatccc     2520

agcactttgg gagaccaagt caggcaatca tctgaagtca ggagttcaag accagcctgg     2580

ccaacatggt gaaagcatgt ctctattaaa aatacaaaaa ttagccgggc gtggtggcgg     2640

gcgcctgtaa tcccaggtat ttggggggac tgagacagga gaatcccttc aacccgggag     2700

gtggaggttg cagtaagtca agatggcacc actgtgctcc agcctggggg acagagcgag     2760

actccatctc aaaaaaaaaa aggaatcgga cgaagaacca caggatgttg aagacaactg     2820

tctgaagtat ttgtgaggga cagcgatgtg gccctctgtg ttaagaataa cgtgtcctgc     2880

tttggcagag agaagaaaat agccactgcc cgctttcaag gcaagatcga ccttttctgt     2940

tttgttttgt ttttctttct ttttcctggc catgaggaca aaaattactg agtggccctt     3000

aaagagggaa gtttgttttc agctgttctc ttttgcccgt aggtgggagg gtggggattg     3060

ctgcgtccta gctagaggaa tggctttgct tgaatgtgta gtgcacacgc acgggtgttt     3120

ctgtgtgcta gttgcttctt gctgctgctt cctgcttgtc tgggactcac atacataacg     3180

tgatatatat atatatatat ataaatgtat aaatatatat tttatttttt tttaaatccc     3240

tggagcttct ggttcctatc agttcctgtt gttaatcgta gaaccgttgt cccttccccc     3300

attcccgtat ccatcatgtt ctttttcttt taaatatcaa tataaaggta aaagaaaaaa     3360

aaaaaaaaaa aaaaaaaaa                                                  3379


<210>  1138
<211>  1866
<212>  DNA
<213>  homo sapiens

<400>  1138
gcccgccccc tttacgtcgt gctctgagga ggccaggaga tttctggcgg cgccggcgcc       60

attttgctgg agcctgcgac cgagtgggag tggagtggag cggctgtggt tgccgactct      120

ttcctcttcc ccacggtcca gtcagcgggt taattaggcc atcggccctc gagccgagac      180

ttgtctctta tttagttctg gggagcgcct cgtcgacatg agtgatgtgg aggaaaacaa      240

cttcgagggc agagagtctc gctctcagtc aaaatctcca acgggaactc ctgctcgtgt      300

aaaatcggag agcaggtcag gatctcgtag tccatcaagg gtttccaaac actctgaatc      360

ccattctcga tcaagatcaa aatccaggtc gaggtcaagg agacattctc atagacgtta      420

cactcgatcc agatcccact ctcactctca taggagacga tctcgaagta gatcatatac      480

accagaatac cggcggcgaa ggagccgaag ccattctcca atgtctaacc ggagaagaca      540

tactggcagc agggcaaatc cagatcccaa cacttgcctt ggagtgtttg gcctcagttt      600

gtacacaaca gagagggatc ttcgtgaagt attttctcga tatggaccat tgagtggtgt      660

caatgtggtt tatgatcagc gaactgggcg atctcgagga tttgcttttg tgtattttga      720

gagaatagat gactcaaagg aggctatgga aagggcaaat ggaatggagc tggatggtag      780

aagaattcgg gtggattatt ctataaccaa gagagcgcac acaccaacac caggcatcta      840

catgggcaga ccaactcata gtggtggggg tggtggagga ggcggcggcg gtggaggtgg      900

aggtggtggc agacgtcgag attcttacta tgatagagga tatgatcgtg ggtatgacag      960

atatgaagac tatgattacc gatacagaag acgatcacct tctccttatt atagtcgata     1020

tagatcacga tcaagatctc gttcctacag cccaagacgc tattgataac ggaatggttg     1080

caattaagga catttttttt cctctttttt tttttttttt ttttaattct gagatttccc     1140

caagctgtgg attcttccta ctccttaaga aaaaaacttt ggtttattta gcatctacac     1200

ttttgtcagt tgtgttgctg ttttccaccc attttattat actcttaaaa gatgtaattg     1260

ttgtcatttt gaacagttaa acatcttgag tataaaaaga accccaatgt tatgttatgc     1320

tttgtaaatt tttttttttg cttttaccta gataaacttc tagctaatca aataaggaaa     1380

gaaactgtct ttttaaagct tcttttgtgt tagatactgt attagagatc tgcatttatc     1440

atgagttcct tttttttttt aactttattt ttgggaaagt aacacatgaa gtagttcagt     1500

catgtcaggt ttgtctgggg tggaatggaa cagtcaggta gttgaaagtt tttttttaga     1560

gatgaaaagc ttgtgaactc ctgtaaaaca tgctgtattt gaaatacatc tgttaaaact     1620

taaaaactaa agtgtgattt tttttgttgt tgttaagttt attgaagttt attcccttaa     1680

tcagtgaagg acaaccctta tttattacct agagcagttg tataattcgc tgttagaaat     1740

tttggtattg ggacagtgga taagcaggtt atcacatagc atagaattct taaaagatac     1800

atgtggggaa aagtagtctc aaataaaagc taatttcttt gaaaaaaaaa aaaaaaaaaa     1860

aaaaaa                                                                1866


<210>  1139
<211>  1866
<212>  DNA
<213>  homo sapiens

<400>  1139
gcccgccccc tttacgtcgt gctctgagga ggccaggaga tttctggcgg cgccggcgcc       60

attttgctgg agcctgcgac cgagtgggag tggagtggag cggctgtggt tgccgactct      120

ttcctcttcc ccacggtcca gtcagcgggt taattaggcc atcggccctc gagccgagac      180

ttgtctctta tttagttctg gggagcgcct cgtcgacatg agtgatgtgg aggaaaacaa      240

cttcgagggc agagagtctc gctctcagtc aaaatctcca acgggaactc ctgctcgtgt      300

aaaatcggag agcaggtcag gatctcgtag tccatcaagg gtttccaaac actctgaatc      360

ccattctcga tcaagatcaa aatccaggtc gaggtcaagg agacattctc atagacgtta      420

cactcgatcc agatcccact ctcactctca taggagacga tctcgaagta gatcatatac      480

accagaatac cggcggcgaa ggagccgaag ccattctcca atgtctaacc ggagaagaca      540

tactggcagc agggcaaatc cagatcccaa cacttgcctt ggagtgtttg gcctcagttt      600

gtacacaaca gagagggatc ttcgtgaagt attttctcga tatggaccat tgagtggtgt      660

caatgtggtt tatgatcagc gaactgggcg atctcgagga tttgcttttg tgtattttga      720

gagaatagat gactcaaagg aggctatgga aagggcaaat ggaatggagc tggatggtag      780

aagaattcgg gtggattatt ctataaccaa gagagcgcac acaccaacac caggcatcta      840

catgggcaga ccaactcata gtggtggggg tggtggagga ggcggcggcg gtggaggtgg      900

aggtggtggc agacgtcgag attcttacta tgatagagga tatgatcgtg ggtatgacag      960

atatgaagac tatgattacc gatacagaag acgatcacct tctccttatt atagtcgata     1020

tagatcacga tcaagatctc gttcctacag cccaagacgc tattgataac ggaatggttg     1080

caattaagga catttttttt cctctttttt tttttttttt ttttaattct gagatttccc     1140

caagctgtgg attcttccta ctccttaaga aaaaaacttt ggtttattta gcatctacac     1200

ttttgtcagt tgtgttgctg ttttccaccc attttattat actcttaaaa gatgtaattg     1260

ttgtcatttt gaacagttaa acatcttgag tataaaaaga accccaatgt tatgttatgc     1320

tttgtaaatt tttttttttg cttttaccta gataaacttc tagctaatca aataaggaaa     1380

gaaactgtct ttttaaagct tcttttgtgt tagatactgt attagagatc tgcatttatc     1440

atgagttcct tttttttttt aactttattt ttgggaaagt aacacatgaa gtagttcagt     1500

catgtcaggt ttgtctgggg tggaatggaa cagtcaggta gttgaaagtt tttttttaga     1560

gatgaaaagc ttgtgaactc ctgtaaaaca tgctgtattt gaaatacatc tgttaaaact     1620

taaaaactaa agtgtgattt tttttgttgt tgttaagttt attgaagttt attcccttaa     1680

tcagtgaagg acaaccctta tttattacct agagcagttg tataattcgc tgttagaaat     1740

tttggtattg ggacagtgga taagcaggtt atcacatagc atagaattct taaaagatac     1800

atgtggggaa aagtagtctc aaataaaagc taatttcttt gaaaaaaaaa aaaaaaaaaa     1860

aaaaaa                                                                1866


<210>  1140
<211>  2234
<212>  DNA
<213>  homo sapiens

<400>  1140
agctgagcta ggagtgaggg atgtgagcca cccccgcttg gcaccccggt ggatctggta       60

acaaagtctg cagcccagag ggcaccttct gcaaacatgt ctgtggatcc cctatccagc      120

aaagctctaa agatcaagcg agagctgagc gagaacacgc cgcacctgtc ggacgaggcg      180

ctgatggggc tgtcggtgcg cgagctgaac cggcatctgc gcgggctctc cgccgaggag      240

gtgacacggc tcaagcagcg gcgccgcaca ctcaaaaacc gtggctacgc cgccagctgc      300

cgcgtgaagc gcgtgtgcca gaaggaggag ctgcagaagc agaagtcgga gctggagcgc      360

gaggtggaca agctggcgcg cgagaacgcc gccatgcgcc tggagctcga cgcgctgcgc      420

ggcaagtgcg aggcgctgca gggcttcgcg cgctccgtgg ccgccgcccg cgggcccgcc      480

acgctcgtgg cgccggccag cgtcatcacc atcgtcaagt ccaccccggg ctcggggtct      540

ggccccgccc acggcccgga ccccgcccac ggcccggcct cctgctccta gtgcccgccc      600

ccgccatgcc tcagccacgc ccctccggcc tcagctccct ccccaaagtg cctgagcgcc      660

gcctctgtgc ccaggtccca tttctctgca gcactggccc cttggtgcac acacattccc      720

ttcgtgggcc ctgtcttcct cttgcagccc cccaaactgg gaccgaatga ccctgggaag      780

gggaacttgg gtaggttggg gatggggcag aggtctggat ctgggatcgc ccttggctga      840

aagtttagcc tttttagatt gagagataca gagccggctt agagaacagc tgttggggga      900

gaagagggca cccctcatct tggaaactgc tcttattgtg ccaatatgcc ctccaaaccc      960

tcccaggatt caaagctagg tttggctgtc tgtgacttac gggaccgtcc tgctgagaaa     1020

ttgcactgaa gagatgcccc cacctctggt tgggcctggg ggtgcctggc cttccgaaac     1080

taaaagagtg ggtgggaaga ctagtgaaac ccagttcacg gatggggaaa caggcctgag     1140

gtcacatttc acttagtggt tgtgttggga ccaaaacctg ggtgtcctca ctgctgccct     1200

gagtccagcc atggttttca gggggacagt ggacagggac tcagaaatgt ggtgggaggg     1260

cctccctggc ttgggagacc gctctctgca agggaggggg agagaagcag agggagagag     1320

aaggtgacac ggatggaaga gtgggaagga gctggcctgg ctcagcccta ggctgtccct     1380

gcagccaggg tgtccggggg ctggccagtc agagaaaggg ggccatggac tgctgtggca     1440

aatagggaga caaggagaca gaccctgcag tcctactaca gtctggagtg gggtcctaag     1500

aagaagggtc ccacctcaac ccctgtcagt gtccactgtg gggtgggggc tgacccctgc     1560

ctttgattgt cattctcctg ggaagcccag tctcagtccc tcccccaaca ctgtccacac     1620

tgcccctccc cactgtttat ttattgcacg gatctaagtt attctcccca gccagagccc     1680

gagctcctgc tccctgggaa aagtggcgta tggccctgag ctgggcttta tattttatat     1740

ctgcaaataa atcacatttt atcttatatt tagggaaagc cggagagcaa caacaaaaaa     1800

tgtttaagcc gggcgcggtg gctcacatct gtaatcccag cactttggga gtccaaggag     1860

ggggatcgct tgagtccagg agtttgagac cagcctggac aacatggtga aaccccatct     1920

ctacaaaaaa tacaaaaatt agccatgcat ggtggctcat gcctgtagtc ccagctactt     1980

gggaggctga ggcaggagga tcacttaagc ccagaaggca gaggttgtag tgagctgaga     2040

tcgcaccact gcactccagc ctgggcaaca tagcaaaatc ctgtctcaaa aaaaaagtta     2100

aaaaatattg cccggctcct agaatttatt tatttcctga cttacagcaa gcgagttatc     2160

gtcttctgta ttttgtagac tttctaaata aagtcaaatt ctttcttttt ccacagagaa     2220

taaaaaaaaa aaaa                                                       2234


<210>  1141
<211>  2383
<212>  DNA
<213>  homo sapiens

<400>  1141
cgggtcggtg acgtcaccgc atgactgggt ttttatgaat gaaaggaatc ctgtgagtga       60

gtaattccgg gaagctcgcc ttacaactcc gcgcggcctc ggccccctgc gccgcccgcc      120

ccacaacaaa actcagcgca gcgctcccgg gcgcccggtt cagagcgacc tgcggctcag      180

agcggagggg agactgaccg gagcgcggat cgggacagcg gccgggacag cggcgagacg      240

cgcgtgtgtg agcgcgccgg accaagcggg cccagaagcg gatcaagcga gagctgagcg      300

agaacacgcc gcacctgtcg gacgaggcgc tgatggggct gtcggtgcgc gagctgaacc      360

ggcatctgcg cgggctctcc gccgaggagg tgacacggct caagcagcgg cgccgcacac      420

tcaaaaaccg tggctacgcc gccagctgcc gcgtgaagcg cgtgtgccag aaggaggagc      480

tgcagaagca gaagtcggag ctggagcgcg aggtggacaa gctggcgcgc gagaacgccg      540

ccatgcgcct ggagctcgac gcgctgcgcg gcaagtgcga ggcgctgcag ggcttcgcgc      600

gctccgtggc cgccgcccgc gggcccgcca cgctcgtggc gccggccagc gtcatcacca      660

tcgtcaagtc caccccgggc tcggggtctg gccccgccca cggcccggac cccgcccacg      720

gcccggcctc ctgctcctag tgcccgcccc cgccatgcct cagccacgcc cctccggcct      780

cagctccctc cccaaagtgc ctgagcgccg cctctgtgcc caggtcccat ttctctgcag      840

cactggcccc ttggtgcaca cacattccct tcgtgggccc tgtcttcctc ttgcagcccc      900

ccaaactggg accgaatgac cctgggaagg ggaacttggg taggttgggg atggggcaga      960

ggtctggatc tgggatcgcc cttggctgaa agtttagcct ttttagattg agagatacag     1020

agccggctta gagaacagct gttgggggag aagagggcac ccctcatctt ggaaactgct     1080

cttattgtgc caatatgccc tccaaaccct cccaggattc aaagctaggt ttggctgtct     1140

gtgacttacg ggaccgtcct gctgagaaat tgcactgaag agatgccccc acctctggtt     1200

gggcctgggg gtgcctggcc ttccgaaact aaaagagtgg gtgggaagac tagtgaaacc     1260

cagttcacgg atggggaaac aggcctgagg tcacatttca cttagtggtt gtgttgggac     1320

caaaacctgg gtgtcctcac tgctgccctg agtccagcca tggttttcag ggggacagtg     1380

gacagggact cagaaatgtg gtgggagggc ctccctggct tgggagaccg ctctctgcaa     1440

gggaggggga gagaagcaga gggagagaga aggtgacacg gatggaagag tgggaaggag     1500

ctggcctggc tcagccctag gctgtccctg cagccagggt gtccgggggc tggccagtca     1560

gagaaagggg gccatggact gctgtggcaa atagggagac aaggagacag accctgcagt     1620

cctactacag tctggagtgg ggtcctaaga agaagggtcc cacctcaacc cctgtcagtg     1680

tccactgtgg ggtgggggct gacccctgcc tttgattgtc attctcctgg gaagcccagt     1740

ctcagtccct cccccaacac tgtccacact gcccctcccc actgtttatt tattgcacgg     1800

atctaagtta ttctccccag ccagagcccg agctcctgct ccctgggaaa agtggcgtat     1860

ggccctgagc tgggctttat attttatatc tgcaaataaa tcacatttta tcttatattt     1920

agggaaagcc ggagagcaac aacaaaaaat gtttaagccg ggcgcggtgg ctcacatctg     1980

taatcccagc actttgggag tccaaggagg gggatcgctt gagtccagga gtttgagacc     2040

agcctggaca acatggtgaa accccatctc tacaaaaaat acaaaaatta gccatgcatg     2100

gtggctcatg cctgtagtcc cagctacttg ggaggctgag gcaggaggat cacttaagcc     2160

cagaaggcag aggttgtagt gagctgagat cgcaccactg cactccagcc tgggcaacat     2220

agcaaaatcc tgtctcaaaa aaaaagttaa aaaatattgc ccggctccta gaatttattt     2280

atttcctgac ttacagcaag cgagttatcg tcttctgtat tttgtagact ttctaaataa     2340

agtcaaattc tttctttttc cacagagaat aaaaaaaaaa aaa                       2383


<210>  1142
<211>  2450
<212>  DNA
<213>  homo sapiens

<400>  1142
cgggtcggtg acgtcaccgc atgactgggt ttttatgaat gaaaggaatc ctgtgagtga       60

gtaattccgg gaagctcgcc ttacaactcc gcgcggcctc ggccccctgc gccgcccgcc      120

ccacaacaaa actcagcgca gcgctcccgg gcgcccggtt cagagcgacc tgcggctcag      180

agcggagggg agactgaccg gagcgcggat cgggacagcg gccgggacag cggcgagacg      240

cgcgtgtgtg agcgcgccgg accaagcggg cccagaagcg ggtctgcagc ccagagggca      300

ccttctgcaa acatgtctgt ggatccccta tccagcaaag ctctaaagat caagcgagag      360

ctgagcgaga acacgccgca cctgtcggac gaggcgctga tggggctgtc ggtgcgcgag      420

ctgaaccggc atctgcgcgg gctctccgcc gaggaggtga cacggctcaa gcagcggcgc      480

cgcacactca aaaaccgtgg ctacgccgcc agctgccgcg tgaagcgcgt gtgccagaag      540

gaggagctgc agaagcagaa gtcggagctg gagcgcgagg tggacaagct ggcgcgcgag      600

aacgccgcca tgcgcctgga gctcgacgcg ctgcgcggca agtgcgaggc gctgcagggc      660

ttcgcgcgct ccgtggccgc cgcccgcggg cccgccacgc tcgtggcgcc ggccagcgtc      720

atcaccatcg tcaagtccac cccgggctcg gggtctggcc ccgcccacgg cccggacccc      780

gcccacggcc cggcctcctg ctcctagtgc ccgcccccgc catgcctcag ccacgcccct      840

ccggcctcag ctccctcccc aaagtgcctg agcgccgcct ctgtgcccag gtcccatttc      900

tctgcagcac tggccccttg gtgcacacac attcccttcg tgggccctgt cttcctcttg      960

cagcccccca aactgggacc gaatgaccct gggaagggga acttgggtag gttggggatg     1020

gggcagaggt ctggatctgg gatcgccctt ggctgaaagt ttagcctttt tagattgaga     1080

gatacagagc cggcttagag aacagctgtt gggggagaag agggcacccc tcatcttgga     1140

aactgctctt attgtgccaa tatgccctcc aaaccctccc aggattcaaa gctaggtttg     1200

gctgtctgtg acttacggga ccgtcctgct gagaaattgc actgaagaga tgcccccacc     1260

tctggttggg cctgggggtg cctggccttc cgaaactaaa agagtgggtg ggaagactag     1320

tgaaacccag ttcacggatg gggaaacagg cctgaggtca catttcactt agtggttgtg     1380

ttgggaccaa aacctgggtg tcctcactgc tgccctgagt ccagccatgg ttttcagggg     1440

gacagtggac agggactcag aaatgtggtg ggagggcctc cctggcttgg gagaccgctc     1500

tctgcaaggg agggggagag aagcagaggg agagagaagg tgacacggat ggaagagtgg     1560

gaaggagctg gcctggctca gccctaggct gtccctgcag ccagggtgtc cgggggctgg     1620

ccagtcagag aaagggggcc atggactgct gtggcaaata gggagacaag gagacagacc     1680

ctgcagtcct actacagtct ggagtggggt cctaagaaga agggtcccac ctcaacccct     1740

gtcagtgtcc actgtggggt gggggctgac ccctgccttt gattgtcatt ctcctgggaa     1800

gcccagtctc agtccctccc ccaacactgt ccacactgcc cctccccact gtttatttat     1860

tgcacggatc taagttattc tccccagcca gagcccgagc tcctgctccc tgggaaaagt     1920

ggcgtatggc cctgagctgg gctttatatt ttatatctgc aaataaatca cattttatct     1980

tatatttagg gaaagccgga gagcaacaac aaaaaatgtt taagccgggc gcggtggctc     2040

acatctgtaa tcccagcact ttgggagtcc aaggaggggg atcgcttgag tccaggagtt     2100

tgagaccagc ctggacaaca tggtgaaacc ccatctctac aaaaaataca aaaattagcc     2160

atgcatggtg gctcatgcct gtagtcccag ctacttggga ggctgaggca ggaggatcac     2220

ttaagcccag aaggcagagg ttgtagtgag ctgagatcgc accactgcac tccagcctgg     2280

gcaacatagc aaaatcctgt ctcaaaaaaa aagttaaaaa atattgcccg gctcctagaa     2340

tttatttatt tcctgactta cagcaagcga gttatcgtct tctgtatttt gtagactttc     2400

taaataaagt caaattcttt ctttttccac agagaataaa aaaaaaaaaa                2450


<210>  1143
<211>  5496
<212>  DNA
<213>  homo sapiens

<400>  1143
ctgtggcttg ccccagagct gatccttgtc tttgtccact tctcagcgag gatggcactt       60

cagggagccc ttcccttact atcgcagaga gagcaggccc tccccagtca tgtccaaccc      120

agaactctgt tttgttttct tcatagccct agcatcacag aaaatcaccc tgtgcattca      180

tggatgtcca cgggggcaag ggctttgtgt tgcttaaccc agcatcctga accgtgtttg      240

ttgaatgaat acagaacccc gtttgctctg ggagagcaca gaaaacagtc ttctatcata      300

tatcatagcc agctgcaaac agcagatggc ttcccatatc ccagagagta agaaccagag      360

agagagagaa agagagagag tttgggtctt tctcctctgt gcctgctctc tccagagaaa      420

ctggaggggt agcagttagc attcccccgc tggttccacc aagcacagtc aaggtctcta      480

ggacatggcc acccctcacc tgtggaagcg gtcctgctgg ggtgggtggg tgttagttgg      540

ttctggtttg ggtcagagac acccagtggc ccaggtgggc gtggggccag ggcgcagacg      600

agaaggggca cgagggctcc gctccgagga cccagcggca agcaccggtc ccgggcgcgc      660

cccagcccac ccactcgcgt gcccacggcg gcattattcc ctataaggat ctgaacgatc      720

cgggggcggc cccgccccgt taccccttgc ccccggcccc gccccctttt tggagggccg      780

atgaggtaat gcggctctgc cattggtctg agggggcggg ccccaacagc ccgaggcggg      840

gtccccgggg gcccagcgct atatcactcg gccgcccagg cagcggcgca gagcgggcag      900

caggcaggcg gcgggcgctc agacggcttc tcctcctcct cttgctcctc cagctcctgc      960

tccttcgccg ggaggccgcc cgccgagtcc tgcgccagcg ccgaggcagc ctcgctgcgc     1020

cccatcccgt cccgccgggc actcggaggg cagcgcgccg gaggccaagg ttgccccgca     1080

cggcccggcg ggcgagcgag ctcgggctgc agcagccccg ccggcggcgc gcacggcaac     1140

tttggagagg cgagcagcag ccccggcagc ggcggcagca gcggcaatga ccccttggct     1200

cgggctcatc gtgctcctgg gcagctggag cctgggggac tggggcgccg aggcgtgcac     1260

atgctcgccc agccaccccc aggacgcctt ctgcaactcc gacatcgtga tccgggccaa     1320

ggtggtgggg aagaagctgg taaaggaggg gcccttcggc acgctggtct acaccatcaa     1380

gcagatgaag atgtaccgag gcttcaccaa gatgccccat gtgcagtaca tccatacgga     1440

agcttccgag agtctctgtg gccttaagct ggaggtcaac aagtaccagt acctgctgac     1500

aggtcgcgtc tatgatggca agatgtacac ggggctgtgc aacttcgtgg agaggtggga     1560

ccagctcacc ctctcccagc gcaaggggct gaactatcgg tatcacctgg gttgtaactg     1620

caagatcaag tcctgctact acctgccttg ctttgtgact tccaagaacg agtgtctctg     1680

gaccgacatg ctctccaatt tcggttaccc tggctaccag tccaaacact acgcctgcat     1740

ccggcagaag ggcggctact gcagctggta ccgaggatgg gcccccccgg ataaaagcat     1800

catcaatgcc acagacccct gagcgccaga ccctgcccca cctcacttcc ctcccttccc     1860

gctgagcttc ccttggacac taactcttcc cagatgatga caatgaaatt agtgcctgtt     1920

ttcttgcaaa tttagcactt ggaacattta aagaaaggtc tatgctgtca tatggggttt     1980

attgggaact atcctcctgg ccccaccctg ccccttcttt ttggttttga catcattcat     2040

ttccacctgg gaatttctgg tgccatgcca gaaagaatga ggaacctgta ttcctcttct     2100

tcgtgataat ataatctcta tttttttagg aaaacaaaaa tgaaaaacta ctccatttga     2160

ggattgtaat tcccacccct cttgcttctt ccccacctca ccatctccca gaccctcttc     2220

cctttgccct tctcctccaa tacataaagg acacagacaa ggaacttgct gaaaggccaa     2280

ccatttcagg atcagtcaaa ggcagcaagc agatagactc aaggtgtgtg aaagatgtta     2340

tacaccagga gctgccactg catgtcccaa ccagactgtg tctgtctgtg tctgcatgta     2400

agagtgaggg agggaaggaa ggaactacaa gagagtcgga gatgatgcag cacacacaca     2460

attccccagc ccagtgatgc ttgtgttgac cagatgttcc tgagtctgga gcaagcaccc     2520

aggccagaat aacagagctt tcttagttgg tgaagactta aacatctgcc tgaggtcagg     2580

aggcaatttg cctgccttgt acaaaagctc aggtgaaaga ctgagatgaa tgtctttcct     2640

ctccctgcct cccaccagac ttcctcctgg aaaacgcttt ggtagatttg gccaggagct     2700

ttcttttatg taaattggat aaatacacac accatacact atccacagat atagccaagt     2760

agatttgggt agaggatact atttccagaa tagtgtttag ctcacctagg gggatatgtt     2820

tgtatacaca tttgcatata cccacatggg gacataagct aattttttta caggacacag     2880

aattctgttc aatgctgtta aatatgccaa tagtttaatc tcttctattt tgttgtcgtt     2940

gcttgtttga agaaaatcat gacattccaa gttgacattt ttttttcatt ttaattaaaa     3000

tttgaaattc tgaacaccgt cagcaccctc tcttccctat catgggtcat ctgacccctg     3060

tccgtctcct tgtccctgct tcatgtttgg gggcctttct ttaactgcct tcctggctta     3120

gctcagatgg cagatgagag tgtagtcaag ggcctgggca caggagggag agctgcagag     3180

tgtcctgcct gccttggctg gagggacacc tctcctgggt gtggagacag cttggttccc     3240

tttccctagc tccctggtgg gtgaatgcca cctcctgaga tcctcacctc ttggaattaa     3300

aattgttggt cactggggaa agcctgagtt tgcaaccagt tgtagggttt ctgttgtgtt     3360

tttttttttt tttttgaaat aaaactataa tataaattct cctattaaat aaaattattt     3420

taagttttag tgtcaaaagt gagatgctga gagtaggtga taatgtatat tttacagagt     3480

gggggttggc aggatggtga cattgaacat gattgctctc tgtctctttt ttcagcttat     3540

gggtatttat cttctattag tatttgtatc ttcagttcat tccactttag gaaacagagc     3600

tgccaattga aacagaagaa gaaaaaaaaa aaaagcagca gacaacacac tgtagagtct     3660

tgcacacaca caagtgccca ggcaaggtgc ttggcagaac cgcagagtgg gaagagagta     3720

ccggcatcgg gtttccttgg gatcaatttc attaccgtgt acctttccca ttgtggtcat     3780

gccatttggc agggggagaa tgggaggctt ggccttcttt gtgaggcagt gtgagcagaa     3840

gctgatgcca gcatgtcact ggttttgaag ggatgagccc agacttgatg ttttgggatt     3900

gtccttattt taacctcaag gtctcgcatg gtggggcccc tgaccaacct acacaagttc     3960

cctcccacaa gtggacatca gtgtcttctc tgtgaggcat ctggccattc gcactccctg     4020

gtgtggtcag cctctctcac acaaggagga acttgggtga aggctgagtg tgaggcacct     4080

gaagtttccc tgcggagtcg ataaattagc agaaccacat ccccatctgt taggccttgg     4140

tgaggaggcc ctgggcaaag aagggtcttt cgcaaagcga tgtcagaggg cggttttgag     4200

ctttctataa gctatagctt tgtttatttc acccgttcac ttactgtata atttaaaatc     4260

atttatgtag ctgagacact tctgtatttc aatcatatca tgaacatttt attttgctaa     4320

atcttgtgtc atgtgtaggc tgtaatatgt gtacattgtg tttaagagaa aaatgaaacc     4380

cacatgccgc cattttcctg aatcaaattc tgcagtggaa tggagaggaa aatacttcta     4440

ggcaagcagc tagactggtg aattggggga aatagaagga actagtaact gagactcctc     4500

cagcctcctc cctattggaa tcccaatggc tcctggagta ggaaaaaagt ttaaactaca     4560

ttcatgttct tgttctgtgt cactcggccc tgggtagtct accatttact tcaccccaag     4620

tcctgctgcc catccagttg ggaagccatg attttcctaa gaatccaggg ccatgggaga     4680

tacaattcca agttctcgct tcctcctttg ggcatctctt ctgcctccca atcaaggaag     4740

ctccatgctc aggctctcag ctctcgggcc agtgctctgc tctgtccagg gtaggtaata     4800

ctgggagact cctgtctttt accctcccct cgttccagac ctgcctcatg gtggcaacat     4860

ggttcttgaa caattaaaga aacaaatgac tttttggaat agccctgtct agggcaaact     4920

gtggccccca ggagacacta cccttccatg ccccagacct ctgtcttgca tgtgacaatt     4980

gacaatctgg actaccccaa gatggcaccc aagtgtttgg cttctggcta cctaaggtta     5040

acatgtcact agagtatttt tatgagagac aaacattata aaaatctgat ggcaaaagca     5100

aaacaaaatg gaaagtaggg gaggtggatg tgacaacaac ttccaaattg gctctttgga     5160

ggcgagagga aggggagaac ttggagaata gtttttgctt tgggggtaga ggcttcttag     5220

attctcccag catccgcctt tccctttagc cagtctgctg tcctgaaacc cagaagtgat     5280

ggagagaaac caacaagaga tctcgaaccc tgtctagaag gaatgtattt gttgctaaat     5340

ttcgtagcac tgtttacagt tttcctccat gttatttatg aattttatat tccgtgaatg     5400

tatattgtct tgtaatgttg cataatgttc actttttata gtgtgtcctt tattctaaac     5460

agtaaagtgg ttttatttct atcacaaaaa aaaaaa                               5496


<210>  1144
<211>  3996
<212>  DNA
<213>  homo sapiens

<400>  1144
agtttctgcc aggagctaat atggcttcct tagttacacc gttctctctc ttcacctaat       60

cagcgacctt actttcccag accagactgt cgagcaggag ctaagactcc ttttcccctc      120

tgctgaccgc cactacagga gcggttgaag ccagacgacc accttgtgga gttaaactcc      180

gtaaccaggg agcaccactt ccgctgacgt cattacggcg acacgtggat ccaagatggc      240

gacggcgatg gattggttgc cgtggtcttt actgcttttc tccctgatgt gtgaaacaag      300

cgccttctat gtgcctgggg tcgcgcctat caacttccac cagaacgatc ccgtagaaat      360

caaggctgtg aagctcacca gctctcgaac ccagctacct tatgaatact attcactgcc      420

cttctgccag cccagcaaga taacctacaa ggcagagaat ctgggagagg tgctgagagg      480

ggaccggatt gtcaacaccc ctttccaggt tctcatgaac agcgagaaga agtgtgaagt      540

tctgtgcagc cagtccaaca agccagtgac cctgacagtg gagcagagcc gactcgtggc      600

cgagcggatc acagaagact actacgtcca cctcattgct gacaacctgc ctgtggccac      660

ccggctggag ctctactcca accgagacag cgatgacaag aagaaggaaa aagatgtgca      720

gtttgaacac ggctaccggc tcggcttcac agatgtcaac aagatctacc tgcacaacca      780

cctctcattc atcctttact atcatcggga ggacatggaa gaggaccagg agcacacgta      840

ccgtgtcgtc cgcttcgagg tgattcccca gagcatcagg ctggaggacc tcaaagcaga      900

tgagaagagt tcgtgcactc tgcctgaggg taccaactcc tcgccccaag aaattgaccc      960

caccaaggag aatcagctgt acttcaccta ctctgtccac tgggaggaaa gtgatatcaa     1020

atgggcctct cgctgggaca cttacctgac catgagtgac gtccagatcc actggttttc     1080

tatcattaac tccgttgttg tggtcttctt cctgtcaggt atcctgagca tgattatcat     1140

tcggaccctc cggaaggaca ttgccaacta caacaaggag gatgacattg aagacaccat     1200

ggaggagtct gggtggaagt tggtgcacgg cgacgtcttc aggccccccc agtaccccat     1260

gatcctcagc tccctgctgg gctcaggcat tcagctgttc tgtatgatcc tcatcgtcat     1320

ctttgtagcc atgcttggga tgctgtcgcc ctccagccgg ggagctctca tgaccacagc     1380

ctgcttcctc ttcatgttca tgggggtgtt tggcggattt tctgctggcc gtctgtaccg     1440

cactttaaaa ggccatcggt ggaagaaagg agccttctgt acggcaactc tgtaccctgg     1500

tgtggttttt ggcatctgct tcgtattgaa ttgcttcatt tggggaaagc actcatcagg     1560

agcggtgccc tttcccacca tggtggctct gctgtgcatg tggttcggga tctccctgcc     1620

cctcgtctac ttgggctact acttcggctt ccgaaagcag ccatatgaca accctgtgcg     1680

caccaaccag attccccggc agatccccga gcagcggtgg tacatgaacc gatttgtggg     1740

catcctcatg gctgggatct tgcccttcgg cgccatgttc atcgagctct tcttcatctt     1800

cagtgctatc tgggagaatc agttctatta cctctttggc ttcctgttcc ttgttttcat     1860

catcctggtg gtatcctgtt cacaaatcag catcgtcatg gtgtacttcc agctgtgtgc     1920

agaggattac cgctggtggt ggagaaattt cctagtctcc gggggctctg cattctacgt     1980

cctggtttat gccatctttt atttcgttaa caagctggac atcgtggagt tcatcccctc     2040

tctcctctac tttggctaca cggccctcat ggtcttgtcc ttctggctgc taacgggtac     2100

catcggcttc tatgcagcct acatgtttgt tcgcaagatc tatgctgctg tgaagataga     2160

ctgattggag tggaccacgg ccaagcttgc tccgtcctcg gacaggaagc caccctgcgt     2220

gggggactgc aggcacgcaa aataaaataa ctcctgctcg tttggaatgt aactcctggc     2280

acagtgttcc tggatcctgg ggctgcgtgg ggggcgggag ggcctgtaga taatcttgcg     2340

tttttcgtca tcttattcca gttctgtggg ggatgagttt ttttgtgggt tgctttttct     2400

tcagtgctaa gaaagttccc tccaacagga actctctgac ctgtttattc aggtgtattt     2460

ctggtttgga tttttttttc cttctttgtt ttaacaaatg gatccaggat ggataaatcc     2520

accgagataa gggttttggt cactgtctcc acctcagttc ctcagggctg ttggccaccc     2580

tatgactaac tggaagagga cacgccagag cttcagtgag gtttccgagc ctctccctgc     2640

ccatcctcac cactgaggcc acgacaaagc acagctccag ctcggacagc accctcagtg     2700

ccagccagcc tctgccagac ctctctttcc ctcttctccc cagcctcctc cagggctgcc     2760

caaggcaggg tttccagcca ggcctcgggg tcatcttttc accaggagca aacccaagtc     2820

ttagttgcta caagaaaatc ccctggaagt actgggggcc aggttcccca gacagcagga     2880

attgcccctg ttcagagcag ccggagtttg ctggaccaca aggaagaaga gaagagactt     2940

gcagtgaact gtttttgtgc caagaaaccc tggacctggg gccaagtatt tcccaagcca     3000

agcatccact tgtctgtgtc tgggaaggga tggccaaggc cgctagggtc cttacccctc     3060

aggatcactc cccagccctt tcctcaggag gtaccgctct ccaaggtgtg ctagcagtgg     3120

gccctgccca acttcaggca gaacagggag gcccagagat tacagatccc ctcctgtaag     3180

tggccaggca ttctctccct gccctctctg gcctctgggg tcatactcac ttctttagcc     3240

agccccatcc cctccacccc acacctgagt tcttgcctcc tccttttggg gacacccaaa     3300

acactgcttg tgagaaggaa gatggaaggt aagttctgtc gttctttccc caatccccag     3360

gaatggacaa gaagccaact tagaaagaag ggtctcacgt ggctggcctg gctcctccgt     3420

agacccctgt tcttttcaac ctctgcccac ccgtgcatgt catcacaaac atttgctctt     3480

aagttacaag agaccacatc cacccaggga ttagggttca agtagcagct gctaaccctt     3540

gcaccagccc ttgtgggact cccaacacaa gacaaagctc aggatgctgg tgatgctagg     3600

aagatgtccc tcccctcact gccccacatt ctcccagtgg ctctaccagc ctcacccatc     3660

aaaccagtga atttctcaat cttgcctcac agtgactgca gcgccaagcg gcatccacca     3720

agcatcaagt tggagaaaag ggaacccaag cagtagagag cgatattgga gtcttttgtt     3780

cattcaaatc ttggattttt ttttttccct aagagattct ctttttaggg ggaatgggaa     3840

acggacacct cataaagggt tcaaagatca tcaatttttc tgacttttta aatcattatc     3900

attattattt ttaattaaaa aaatgcctgt atgccttttt ttggtcggat tgtaaataaa     3960

tataccattg tcctactgaa aaaaaaaaaa aaaaaa                               3996


<210>  1145
<211>  5063
<212>  DNA
<213>  homo sapiens

<400>  1145
gccttagaaa agttaacgag aaccagatgt ggtggccact gccgaacttt ctcagagccg       60

gtgattggtc cccagccgag ggcctcagcc aattagcttg ctgggtgggc ctggagtccc      120

gccccgccca ggcgcccgcg gagatccagg ttcgaggctg gcgcggcgcg gagagtgggc      180

tggaggccgg ggcgggacgc gttgtgcagc gggtaagcgc acggccgagc gagcatggag      240

ggggaccggg tggccgggcg gccggtgctg tcgtcgttac cagtgctact gctgctgccg      300

ttgctaatgt tgcgggccgc ggcgctgcac ccagacgagc tcttcccaca cggggagtcg      360

tggggggacc agctcctgca ggaaggcgac gacgaaagct cagccgtggt gaagctggcg      420

aatcccctgc acttctacga agcccgattc agcaacctct acgtgggcac caacggcatc      480

atctccactc aggacttccc cagggaaacg cagtatgtgg actatgattt ccccaccgac      540

ttcccggcca tcgccccttt tctggcggac atcgacacga gccacggcag aggccgagtc      600

ctgtaccgag aggacacctc ccccgcagtg ctgggcctgg ccgcccgcta tgtgcgcgct      660

ggcttcccgc gctctgcgcg ctttaccccc acccacgcct tcctggccac ctgggagcag      720

gtaggcgctt acgaggaggt caagcgcggg gcgctgccct cgggagagct gaacactttc      780

caggcagttt tggcatctga tgggtctgat agctacgccc tctttcttta tcctgccaac      840

ggcctgcagt tccttggaac ccgccccaaa gagtcttaca atgtccagct tcagcttcca      900

gctcgggtgg gcttctgccg aggggaggct gatgatctga agtcagaagg accatatttc      960

agcttgacta gcactgaaca gtctgtgaaa aatctctatc aactaagcaa cctggggatc     1020

cctggagtgt gggctttcca tatcggcagc acttccccgt tggacaatgt caggccagct     1080

gcagttggag acctttccgc tgcccactct tctgttcccc tgggacgttc cttcagccat     1140

gctacagccc tggaaagtga ctataatgag gacaatttgg attactatga tgtgaatgag     1200

gaggaagctg aataccttcc gggtgaacca gaggaggcat tgaatggcca cagcagcatt     1260

gatgtttcct tccaatccaa agtggataca aagcctttag aggaatcttc caccttggat     1320

cctcacacca aagaaggaac atctctggga gaggtagggg gcccagattt aaaaggccaa     1380

gttgagccct gggatgagag agagaccaga agcccagctc caccagaggt agacagagat     1440

tcactggctc cttcctggga aaccccacca ccgtaccccg aaaacggaag catccagccc     1500

tacccagatg gagggccagt gccttcggaa atggatgttc ccccagctca tcctgaagaa     1560

gaaattgttc ttcgaagtta ccctgcttca ggtcacacta cacccttaag tcgagggacg     1620

tatgaggtgg gactggaaga caacataggt tccaacaccg aggtcttcac gtataatgct     1680

gccaacaagg aaacctgtga acacaaccac agacaatgct cccggcatgc cttctgcacg     1740

gactatgcca ctggcttctg ctgccactgc caatccaagt tttatggaaa tgggaagcac     1800

tgtctgcctg aaggggcacc tcaccgagtg aatgggaaag tgagtggcca cctccacgtg     1860

ggccatacac ccgtgcactt cactgatgtg gacctgcatg cgtatatcgt gggcaatgat     1920

ggcagagcct acacggccat cagccacatc ccacagccag cagcccaggc cctcctcccc     1980

ctcacaccaa ttggaggcct gtttggctgg ctctttgctt tagaaaaacc tggctctgag     2040

aacggcttca gcctcgcagg tgctgccttt acccatgaca tggaagttac attctacccg     2100

ggagaggaga cggttcgtat cactcaaact gctgagggac ttgacccaga gaactacctg     2160

agcattaaga ccaacattca aggccaggtg ccttacgtct cagcaaattt cacagcccac     2220

atctctccct acaaggagct gtaccactac tccgactcca ctgtgacctc tacaagttcc     2280

agagactact ctctgacttt tggtgcaatc aaccaaacat ggtcctaccg catccaccag     2340

aacatcactt accaggtgtg caggcacgcc cccagacacc cgtccttccc caccacccag     2400

cagctgaacg tggaccgggt ctttgccttg tataatgacg aagaaagagt gcttagattt     2460

gctgtgacca atcaaattgg cccggtcaaa gaggattcag accccactcc ggggaatcct     2520

tgctatgatg ggagccacat gtgtgacaca acagcacggt gccatccagg gacaggtgta     2580

gattacacct gtgagtgcgc atctgggtac cagggagatg gacggaactg tgtggatgaa     2640

aatgaatgtg caactggctt tcatcgctgt ggccccaact ctgtatgtat caacttgcct     2700

ggaagctaca ggtgtgagtg ccggagtggt tatgagtttg cagatgaccg gcatacttgc     2760

atcttgatca ccccacctgc caacccctgt gaggatggca gtcatacctg tgctcctgct     2820

gggcaggccc ggtgtgttca ccatggaggc agcacgttca gctgtgcctg cctgcctggt     2880

tatgccggcg atgggcacca gtgcactgat gtagatgaat gctcagaaaa cagatgtcac     2940

cctgcagcta cctgctacaa tactcctggt tccttctcct gccgttgtca acccggatat     3000

tatggggatg gatttcagtg catacctgac tccacctcaa gcctgacacc ctgtgaacaa     3060

cagcagcgcc atgcccaggc ccagtatgcc taccctgggg cccggttcca catcccccaa     3120

tgcgacgagc agggcaactt cctgccccta cagtgtcatg gcagcactgg tttctgctgg     3180

tgcgtggacc ctgatggtca tgaagttcct ggtacccaga ctccacctgg ctccaccccg     3240

cctcactgtg gaccatcacc agagcccacc cagaggcccc cgaccatctg tgagcgctgg     3300

agggaaaacc tgctggagca ctacggtggc accccccggg atgaccagta cgtgccccag     3360

tgcgatgacc tgggccactt catccccctg cagtgccacg gaaagagcga cttctgctgg     3420

tgtgtggaca aagatggcag agaggtgcag ggcacccgct cccagccagg caccacccct     3480

gcgtgtatac ccaccgtcgc tccacccatg gtccggccca cgccccggcc agatgtgacc     3540

cctccatctg tgggcacctt cctgctctat actcagggcc agcagattgg ctacttaccc     3600

ctcaatggca ccaggcttca gaaggatgca gctaagaccc tgctgtctct gcatggctcc     3660

ataatcgtgg gaattgatta cgactgccgg gagaggatgg tgtactggac agatgttgct     3720

ggacggacaa tcagccgtgc tggtctggaa ctgggagcag agcctgagac gatcgtgaat     3780

tcaggtctga taagccctga aggacttgcc atagaccaca tccgcagaac aatgtactgg     3840

acggacagtg tcctggataa gatagagagc gccctgctgg atggctctga gcgcaaggtc     3900

ctcttctaca cagatctggt gaatccccgt gccatcgctg tggatccaat ccgaggcaac     3960

ttgtactgga cagactggaa tagagaagct cctaaaattg aaacgtcatc tttagatgga     4020

gaaaacagaa gaattctgat caatacagac attggattgc ccaatggctt aacctttgac     4080

cctttctcta aactgctctg ctgggcagat gcaggaacca aaaaactgga gtgtacacta     4140

cctgatggaa ctggacggcg tgtcattcaa aacaacctca agtacccctt cagcatcgta     4200

agctatgcag atcacttcta ccacacagac tggaggaggg atggtgttgt atcagtaaat     4260

aaacatagtg gccagtttac tgatgagtat ctcccagaac aacgatctca cctctacggg     4320

ataactgcag tctaccccta ctgcccaaca ggaagaaagt aagtacagta atgtaaagga     4380

agacttggag tttacaatca gaacctggac cctaaagaac agtgactgca aaggcaaaga     4440

aagtaaaaaa ggaattggcc attagacgtt cctgagcatc caagatgaac attttgtagt     4500

gcaaaaagac ttttgtgaaa agctgatacc tcaatcttta ctactgtatt tttaaaaatg     4560

aaggttgtta ttgcaagttt aaaaaggtaa cagaatttta actgttgctt attaaagcaa     4620

cttcttgtaa acatttatca ttaatattta aaagatcaaa ttcattcaac taagaattag     4680

agtttaagac tctaaacctg atttttgcca tggattcctt ctggccaaga aattaaagca     4740

catgtgatca atataacaat ataatcctaa accttgacag ttggagaagc caatgcagaa     4800

ctgatgggaa aggaccaatt atttatagtt tcccaacaaa agttctaaga ttttttacct     4860

ctgcatcagt gcatttctat ttatatcaaa aggtgctaaa atgattcaat ttgcattttc     4920

tgatcctgta gtgcctctat agaagtaccc acagaaagta aagtatcaca tttataaata     4980

ccaaagatgt aacaatttta aaattttcta gattactcca ataaagtgtt ttaagttttc     5040

ctatgaaaaa aaaaaaaaaa aaa                                             5063


<210>  1146
<211>  6305
<212>  DNA
<213>  homo sapiens

<400>  1146
tttcccgcat gaaaattact taaacgttgc acacaacgtt tcacaaaatc ttttgtgaaa       60

gaagaaaagg aaattcagtg tgtgagtctc agcaggagtt aagctaatgc agcttaaaat      120

aatgccgaaa aagaagcgct tatctgcggg cagagtgccc ctgattctct tcctgtgcca      180

gatgattagt gcactggaag tacctcttga tccaaaactt cttgaagact tggtacagcc      240

tccaaccatc acccaacagt ctccaaaaga ttacattatt gaccctcggg agaatattgt      300

aatccagtgt gaagccaaag ggaaaccgcc cccaagcttt tcctggaccc gtaatgggac      360

tcattttgac atcgataaag accctctggt caccatgaag cctggcacag gaacgctcat      420

aattaacatc atgagcgaag ggaaagctga gacctatgaa ggagtctatc agtgtacagc      480

aaggaacgaa cgcggagctg cagtttctaa taacattgtt gtccgcccat ccagatcacc      540

attgtggacc aaagaaaaac ttgaaccaat cacacttcaa agtggtcagt ctttagtact      600

tccctgcaga cccccaattg gattaccacc acctataata ttttggatgg ataattcctt      660

tcaaagactt ccacaaagtg agagagtttc tcaaggtttg aatggggacc tttatttttc      720

caatgtcctc ccagaggaca cccgcgaaga ctatatctgt tatgctagat ttaatcatac      780

tcaaaccata cagcagaagc aacctatttc tgtgaaggtg atttcagtgg atgaattgaa      840

tgacactata gctgctaatt tgagtgacac tgagttttat ggtgctaaat caagtagaga      900

gaggccacca acatttttaa ctccagaagg caatgcaagt aacaaagagg aattaagagg      960

aaatgtgctt tcactggagt gcattgcaga aggactgcct accccaatta tttactgggc     1020

aaaggaagat ggaatgctac ccaaaaacag gacagtttat aagaactttg agaaaacctt     1080

gcagatcatt catgtttcag aagcagactc tggaaattac caatgtatag caaaaaacgc     1140

attaggagcc atccaccata ccatttctgt tagagttaaa gcggctccat actggatcac     1200

agcccctcaa aatcttgtgc tgtccccagg agaggatggg accttgatct gcagagctaa     1260

tggcaacccc aaacccagaa ttagctggtt aacaaatgga gtcccaatag aaattgcccc     1320

tgatgacccc agcagaaaaa tagatggcga taccattatt ttttcaaatg ttcaagaaag     1380

atcaagtgca gtctatcagt gcaatgcctc taatgaatat ggatatttac tggcaaacgc     1440

atttgtaaat gtgctggctg agccaccacg aatcctcaca cctgcaaaca cactctacca     1500

ggtcattgca aacaggcctg ctttactaga ctgtgccttc tttgggtctc ctctcccaac     1560

catcgagtgg tttaaaggag ctaaaggaag tgctcttcat gaagatattt atgttttaca     1620

tgaaaatgga actttggaaa ttcctgtggc ccaaaaggac agtacaggaa cttatacgtg     1680

tgttgcaagg aataaattag ggatggcgaa gaatgaagtt cacttagaaa tcaaagatcc     1740

tacatggatc gttaaacagc ccgaatatgc agttgtgcaa agagggagca tggtgtcctt     1800

tgaatgcaaa gtgaaacatg atcacacctt atccctcact gtcctgtggc tgaaggacaa     1860

cagggaactg cccagtgatg aaaggttcac tgttgacaag gatcatctag tggtagctga     1920

tgtcagtgac gatgacagcg ggacctacac gtgtgtggcc aacaccactc tggacagcgt     1980

ctccgccagc gctgtgctta gcgttgttgc tcctactcca actccagctc ccgtttacga     2040

tgtcccaaat cctccctttg acttagaact gacagatcaa cttgacaaaa gtgttcagct     2100

gtcatggacc ccaggcgatg acaacaatag ccccattaca aaattcatca tcgaatatga     2160

agatgcaatg cacaagccag ggctgtggca ccaccaaact gaagtttctg gaacacagac     2220

cacagcccag ctgaagctgt ctccttacgt gaactactcc ttccgcgtga tggcagtgaa     2280

cagcattggg aagagcttgc ccagcgaggc gtctgagcag tatttgacga aagcctcaga     2340

accagataaa aaccccacag ctgtggaagg actgggatca gagcctgata atttggtgat     2400

tacgtggaag cccttgaatg gtttcgaatc taatgggcca ggccttcagt acaaagttag     2460

ctggcgccag aaagatggtg atgatgaatg gacatctgtg gttgtggcaa atgtatccaa     2520

atatattgtc tcaggcacgc caacctttgt tccatacctg atcaaagttc aggccctgaa     2580

tgacatgggg tttgcccccg agccagctgt agtcatggga cattctggag aagacctccc     2640

aatggtggct cctgggaacg tgcgtgtgaa tgtggtgaac agtaccttag ccgaggtgca     2700

ctgggaccca gtacctctga aaagcatccg aggacaccta caaggctatc ggatttacta     2760

ttggaagacc cagagttcat ctaaaagaaa cagacgtcac attgagaaaa agatcctcac     2820

cttccaaggc agcaagactc atggcatgtt gccggggcta gagcccttta gccactacac     2880

actgaatgtc cgagtggtca atgggaaagg ggagggccca gccagccctg acagagtctt     2940

taatactcca gaaggagtcc ccagtgctcc ctcgtctttg aagattgtga atccaacact     3000

ggactctctc actttggaat gggatccacc gagccacccg aatggcattt tgacagagta     3060

caccttaaag tatcagccaa ttaacagcac acatgaatta ggccctctgg tagatttgaa     3120

aattcctgcc aacaagacac ggtggacttt aaaaaattta aatttcagca ctcgatataa     3180

gttttatttc tatgcacaaa catcagcagg atcaggaagt caaattacag aggaagcagt     3240

aacaactgtg gatgaagctg gtattcttcc acctgatgta ggtgcaggca aagttcaagc     3300

agtaaatccc aggatcagca atcttactgc tgcagctgct gagacctatg ccaatatcag     3360

ttgggaatat gagggaccag agcatgtgaa cttttatgtt gaatatggtg tagcaggcag     3420

caaagaagaa tggagaaaag aaattgtaaa tggttctcgg agcttctttg ggttaaaggg     3480

tctaatgcca ggaacagcat acaaagttcg agttggtgct gtgggggact ctggttttgt     3540

gagttcagag gatgtgtttg agacaggccc agcgatggca agccggcagg tggatattgc     3600

aactcagggc tggttcattg gtctgatgtg tgctgttgct ctccttatct taattttgct     3660

gattgtttgc ttcatcagaa gaaacaaggg tggtaaatat ccagttaaag aaaaggaaga     3720

tgcccatgct gaccctgaaa tccagcctat gaaggaagat gatgggacat ttggagaata     3780

cagtgatgca gaagaccaca agcctttgaa aaaaggaagt cgaactcctt cagacaggac     3840

tgtgaaaaaa gaagatagtg acgacagcct agttgactat ggagaagggg ttaatggcca     3900

gttcaatgag gatggctcct ttattggaca atacagtggt aagaaagaga aagagccggc     3960

tgaaggaaac gaaagctcag aggcaccttc tcctgtcaac gccatgaatt cctttgttta     4020

atttttaagc tctttgccaa tattccattt ctctagaatg tttatcctaa gcacttgttt     4080

gtcagccctc tcatactatg aacatatggg tagagagtat attttctgct gtatgttagt     4140

attatgagaa tagttacagc aaaaacataa ctcagtcaaa tgatatgtta atatgaactg     4200

gaatgcaaag tgcatacttt ttcattcaaa atgggtattc ttgatttcct cagaactgat     4260

aaaaaataat gcaacatcac caacagatcc tgttatttcc tctgcaggat acagttcaat     4320

atgatgcatg aaaaatgctc cacatttaaa ggacataccc gtgtatgtta tgaaaacatg     4380

gtttgatact ttgtttatac taccctcagc tgaaccccta tatatgaatt ccgttttcat     4440

tgtcaagaat gttactgtag tattctctag aacttcaatg tctttgtgga cattgttgtg     4500

aaattggtga ctatgtatag ctgtcgttag tctttttggg agactgttag gaacagtttg     4560

tacagtatat acttgctaaa tgagttcatt atgacagtca cattgctgat gcttactgag     4620

aactattacc tactcttggc tcctgttact ccgtaggctt cttaatcttc caggcattac     4680

agcagcacag tgttctactt tttacatcat ttctatgttc ggttgttttt aggcataaac     4740

aatgtgtatt gcagtgcatt tcggcatttg tgccatactg aaagaatcaa aaacaaatca     4800

tccaaattaa atttcaaaca ttatttcaga gaacacaggg caagacacat acagtgcctt     4860

cagatattaa gcattccaca acatcgtgca ttctgtatca gctggtccag tccattctgg     4920

gtcctagatt actgtcattg tctaaaagta acttttaaaa agcagagttc atgaaaactg     4980

caatgctggg aaaagaagga aacatgaaaa taaaaataag acagtttatt agaaatagca     5040

tttcctcata agcataaaaa gaaaatcttt gttgccaact gaagcacatg atgattttgt     5100

ggtcctttat ggtttctatt acattcagta agaaagatgt caacatgcta gaaaattaat     5160

tttaaaacta agttattcca acactaaaag catacaacag catgccaaca gtaatatatt     5220

attctccaag actttaccta tgtaagtgtt caaaactctg cagcattaaa caacgtgtat     5280

gcaaattgtt atggatacat ttcagaatct aagaaatcag gcaagtgctt aaaaggccaa     5340

cggtccaagg gattacatct gcagtttaaa aagtaaatat atattctatc gtattcataa     5400

acaatatcta tcaaatgggt tacctccaaa tatgaaaatc tataacaacc tatggttgaa     5460

ggaatgctca gtttcatttg ccaataaatt ggtttctcat aacttgcatc aagtttaatt     5520

ttaagtaaag ctttttatat gtagatattt tgttgaattt gtaaatacac ttaaaatgta     5580

gatgctatat gcttataggt gttacataca aataaacatg caatgtttat gttgtactgt     5640

ataagaggta agctaattaa tgcagtgaat gggattggaa agcatctact taaatatcta     5700

ttgggttccc ccctcccccc accttttttg ctgtgaaact gaaatagtga acttttctac     5760

gtattgacag cagatttttc gatgaaatct tcagagcttt gcctatgggg cacagtaggc     5820

ctagtaacct ggcatgtttg atatatgtag gtaaagcata atttaaagta atcccaggta     5880

aagatggccc taaatacttt catgtctcta tattcatttt tcacagatcc acctgtctct     5940

tgaaaatata aaaagacaaa acaggtttgc cttggcatca gagagcacaa agattaaaag     6000

ttactttaaa tttgccaata ttttgggaga acaataaaac tacatttttt cctcttccat     6060

actggtagat gcgaaattta tctgtgcatg aaagggtcac ttctgtaata gtgcaacaga     6120

tttggtatta aaaattaaat gtggttttaa aagttcctct ctcttttgta atttatgttc     6180

ccaattgagt gtgaatgtcc aagtaatggt gtatgtaatg gtacaggcaa atgtgactgg     6240

atttccctca aaaaagtaac tattaaacag tcttgatctc tttgtgactt ttaacttttt     6300

caaac                                                                 6305


<210>  1147
<211>  6322
<212>  DNA
<213>  homo sapiens

<400>  1147
agtccgagcc tcagacgcgc gggcgcgggg gacggcgcag gggccgcctg gctggagcag       60

ccagagggga tagcttcgtc gagaacggag gacaccggcg gtccagggtc ctgggcagtc      120

gcgccagagc tgagcggagg gcgcggcgcg agaacgaatc tttgtgacat tctctctcag      180

cattctttat cccctgtttg ctgaagactt cgacaaaagc tggtcttagc tgttggcatt      240

ctcctgagaa aaggatagct tcagaaatca gaaaaacatt tgggaggtgt ctagcccagt      300

ggaccttctg aagagcaatg ctaagaagac gtttggttta aagaattaaa aggaagaaca      360

acttaagagc ttcttcaaag tttcccgcat gaaaattact taaacgttgc acacaacgtt      420

tcacaaaatc ttttgtgaaa gaagaaaagg aaattcagtg tgtgagtctc agcaggagtt      480

aagctaatgc agcttaaaat aatgccgaaa aagaagcgct tatctgcggg cagagtgccc      540

ctgattctct tcctgtgcca gatgattagt gcactggaag tacctcttga tctggtacag      600

cctccaacca tcacccaaca gtctccaaaa gattacatta ttgaccctcg ggagaatatt      660

gtaatccagt gtgaagccaa agggaaaccg cccccaagct tttcctggac ccgtaatggg      720

actcattttg acatcgataa agaccctctg gtcaccatga agcctggcac aggaacgctc      780

ataattaaca tcatgagcga agggaaagct gagacctatg aaggagtcta tcagtgtaca      840

gcaaggaacg aacgcggagc tgcagtttct aataacattg ttgtccgccc atccagatca      900

ccattgtgga ccaaagaaaa acttgaacca atcacacttc aaagtggtca gtctttagta      960

cttccctgca gacccccaat tggattacca ccacctataa tattttggat ggataattcc     1020

tttcaaagac ttccacaaag tgagagagtt tctcaaggtt tgaatgggga cctttatttt     1080

tccaatgtcc tcccagagga cacccgcgaa gactatatct gttatgctag atttaatcat     1140

actcaaacca tacagcagaa gcaacctatt tctgtgaagg tgatttcagt ggatgaattg     1200

aatgacacta tagctgctaa tttgagtgac actgagtttt atggtgctaa atcaagtaga     1260

gagaggccac caacattttt aactccagaa ggcaatgcaa gtaacaaaga ggaattaaga     1320

ggaaatgtgc tttcactgga gtgcattgca gaaggactgc ctaccccaat tatttactgg     1380

gcaaaggaag atggaatgct acccaaaaac aggacagttt ataagaactt tgagaaaacc     1440

ttgcagatca ttcatgtttc agaagcagac tctggaaatt accaatgtat agcaaaaaac     1500

gcattaggag ccatccacca taccatttct gttagagtta aagcggctcc atactggatc     1560

acagcccctc aaaatcttgt gctgtcccca ggagaggatg ggaccttgat ctgcagagct     1620

aatggcaacc ccaaacccag aattagctgg ttaacaaatg gagtcccaat agaaattgcc     1680

cctgatgacc ccagcagaaa aatagatggc gataccatta ttttttcaaa tgttcaagaa     1740

agatcaagtg cagtctatca gtgcaatgcc tctaatgaat atggatattt actggcaaac     1800

gcatttgtaa atgtgctggc tgagccacca cgaatcctca cacctgcaaa cacactctac     1860

caggtcattg caaacaggcc tgctttacta gactgtgcct tctttgggtc tcctctccca     1920

accatcgagt ggtttaaagg agctaaagga agtgctcttc atgaagatat ttatgtttta     1980

catgaaaatg gaactttgga aattcctgtg gcccaaaagg acagtacagg aacttatacg     2040

tgtgttgcaa ggaataaatt agggatggcg aagaatgaag ttcacttaga aatcaaagat     2100

cctacatgga tcgttaaaca gcccgaatat gcagttgtgc aaagagggag catggtgtcc     2160

tttgaatgca aagtgaaaca tgatcacacc ttatccctca ctgtcctgtg gctgaaggac     2220

aacagggaac tgcccagtga tgaaaggttc actgttgaca aggatcatct agtggtagct     2280

gatgtcagtg acgatgacag cgggacctac acgtgtgtgg ccaacaccac tctggacagc     2340

gtctccgcca gcgctgtgct tagcgttgtt gatgtcccaa atcctccctt tgacttagaa     2400

ctgacagatc aacttgacaa aagtgttcag ctgtcatgga ccccaggcga tgacaacaat     2460

agccccatta caaaattcat catcgaatat gaagatgcaa tgcacaagcc agggctgtgg     2520

caccaccaaa ctgaagtttc tggaacacag accacagccc agctgaagct gtctccttac     2580

gtgaactact ccttccgcgt gatggcagtg aacagcattg ggaagagctt gcccagcgag     2640

gcgtctgagc agtatttgac gaaagcctca gaaccagata aaaaccccac agctgtggaa     2700

ggactgggat cagagcctga taatttggtg attacgtgga agcccttgaa tggtttcgaa     2760

tctaatgggc caggccttca gtacaaagtt agctggcgcc agaaagatgg tgatgatgaa     2820

tggacatctg tggttgtggc aaatgtatcc aaatatattg tctcaggcac gccaaccttt     2880

gttccatacc tgatcaaagt tcaggccctg aatgacatgg ggtttgcccc cgagccagct     2940

gtagtcatgg gacattctgg agaagacctc ccaatggtgg ctcctgggaa cgtgcgtgtg     3000

aatgtggtga acagtacctt agccgaggtg cactgggacc cagtacctct gaaaagcatc     3060

cgaggacacc tacaaggcta tcggatttac tattggaaga cccagagttc atctaaaaga     3120

aacagacgtc acattgagaa aaagatcctc accttccaag gcagcaagac tcatggcatg     3180

ttgccggggc tagagccctt tagccactac acactgaatg tccgagtggt caatgggaaa     3240

ggggagggcc cagccagccc tgacagagtc tttaatactc cagaaggagt ccccagtgct     3300

ccctcgtctt tgaagattgt gaatccaaca ctggactctc tcactttgga atgggatcca     3360

ccgagccacc cgaatggcat tttgacagag tacaccttaa agtatcagcc aattaacagc     3420

acacatgaat taggccctct ggtagatttg aaaattcctg ccaacaagac acggtggact     3480

ttaaaaaatt taaatttcag cactcgatat aagttttatt tctatgcaca aacatcagca     3540

ggatcaggaa gtcaaattac agaggaagca gtaacaactg tggatgaagc gatggcaagc     3600

cggcaggtgg atattgcaac tcagggctgg ttcattggtc tgatgtgtgc tgttgctctc     3660

cttatcttaa ttttgctgat tgtttgcttc atcagaagaa acaagggtgg taaatatcca     3720

gttaaagaaa aggaagatgc ccatgctgac cctgaaatcc agcctatgaa ggaagatgat     3780

gggacatttg gagaatacag tgatgcagaa gaccacaagc ctttgaaaaa aggaagtcga     3840

actccttcag acaggactgt gaaaaaagaa gatagtgacg acagcctagt tgactatgga     3900

gaaggggtta atggccagtt caatgaggat ggctccttta ttggacaata cagtggtaag     3960

aaagagaaag agccggctga aggaaacgaa agctcagagg caccttctcc tgtcaacgcc     4020

atgaattcct ttgtttaatt tttaagctct ttgccaatat tccatttctc tagaatgttt     4080

atcctaagca cttgtttgtc agccctctca tactatgaac atatgggtag agagtatatt     4140

ttctgctgta tgttagtatt atgagaatag ttacagcaaa aacataactc agtcaaatga     4200

tatgttaata tgaactggaa tgcaaagtgc atactttttc attcaaaatg ggtattcttg     4260

atttcctcag aactgataaa aaataatgca acatcaccaa cagatcctgt tatttcctct     4320

gcaggataca gttcaatatg atgcatgaaa aatgctccac atttaaagga catacccgtg     4380

tatgttatga aaacatggtt tgatactttg tttatactac cctcagctga acccctatat     4440

atgaattccg ttttcattgt caagaatgtt actgtagtat tctctagaac ttcaatgtct     4500

ttgtggacat tgttgtgaaa ttggtgacta tgtatagctg tcgttagtct ttttgggaga     4560

ctgttaggaa cagtttgtac agtatatact tgctaaatga gttcattatg acagtcacat     4620

tgctgatgct tactgagaac tattacctac tcttggctcc tgttactccg taggcttctt     4680

aatcttccag gcattacagc agcacagtgt tctacttttt acatcatttc tatgttcggt     4740

tgtttttagg cataaacaat gtgtattgca gtgcatttcg gcatttgtgc catactgaaa     4800

gaatcaaaaa caaatcatcc aaattaaatt tcaaacatta tttcagagaa cacagggcaa     4860

gacacataca gtgccttcag atattaagca ttccacaaca tcgtgcattc tgtatcagct     4920

ggtccagtcc attctgggtc ctagattact gtcattgtct aaaagtaact tttaaaaagc     4980

agagttcatg aaaactgcaa tgctgggaaa agaaggaaac atgaaaataa aaataagaca     5040

gtttattaga aatagcattt cctcataagc ataaaaagaa aatctttgtt gccaactgaa     5100

gcacatgatg attttgtggt cctttatggt ttctattaca ttcagtaaga aagatgtcaa     5160

catgctagaa aattaatttt aaaactaagt tattccaaca ctaaaagcat acaacagcat     5220

gccaacagta atatattatt ctccaagact ttacctatgt aagtgttcaa aactctgcag     5280

cattaaacaa cgtgtatgca aattgttatg gatacatttc agaatctaag aaatcaggca     5340

agtgcttaaa aggccaacgg tccaagggat tacatctgca gtttaaaaag taaatatata     5400

ttctatcgta ttcataaaca atatctatca aatgggttac ctccaaatat gaaaatctat     5460

aacaacctat ggttgaagga atgctcagtt tcatttgcca ataaattggt ttctcataac     5520

ttgcatcaag tttaatttta agtaaagctt tttatatgta gatattttgt tgaatttgta     5580

aatacactta aaatgtagat gctatatgct tataggtgtt acatacaaat aaacatgcaa     5640

tgtttatgtt gtactgtata agaggtaagc taattaatgc agtgaatggg attggaaagc     5700

atctacttaa atatctattg ggttcccccc tccccccacc ttttttgctg tgaaactgaa     5760

atagtgaact tttctacgta ttgacagcag atttttcgat gaaatcttca gagctttgcc     5820

tatggggcac agtaggccta gtaacctggc atgtttgata tatgtaggta aagcataatt     5880

taaagtaatc ccaggtaaag atggccctaa atactttcat gtctctatat tcatttttca     5940

cagatccacc tgtctcttga aaatataaaa agacaaaaca ggtttgcctt ggcatcagag     6000

agcacaaaga ttaaaagtta ctttaaattt gccaatattt tgggagaaca ataaaactac     6060

attttttcct cttccatact ggtagatgcg aaatttatct gtgcatgaaa gggtcacttc     6120

tgtaatagtg caacagattt ggtattaaaa attaaatgtg gttttaaaag ttcctctctc     6180

ttttgtaatt tatgttccca attgagtgtg aatgtccaag taatggtgta tgtaatggta     6240

caggcaaatg tgactggatt tccctcaaaa aagtaactat taaacagtct tgatctcttt     6300

gtgactttta actttttcaa ac                                              6322


<210>  1148
<211>  5827
<212>  DNA
<213>  homo sapiens

<400>  1148
ggcgcgggtg cgggcgcccc agccggccgc gatcgcggga tttctgcgcc aggagatgag       60

gggcggtaga gccctggaat ggagatgtcc ttgacgcctg ggcagaggct gcagctgcag      120

gaccctgtgg ccactggaga taagtaatgg tgccatttga acacctactg gaaacggggc      180

aggaacagtg agtgacccca ggcgagcaca ggcaggtgcc aggagccagg atgcaaggat      240

gacgcctccg gaggccctgg cctcactccc acctgggcgc taggagccat cccggggctc      300

cagccaggag ccctgctgcc caggggcatg gccaaacctt tcttccgact ccagaagttt      360

ctccgccgaa cacagttcct gctgttcttc ctcacggctg cctacctgat gaccggcagc      420

ctgctgctgc tgcagcgggt ccgcgtggct ctcccacagg gcccccgggc acccggcccc      480

ctgcagacct tgccagtggc cgccgtggcg ctgggcgtgg gcttgctgga cagcagagcc      540

ctgcacgacc ctcgagtcag cccagagctg ctgctgggtg tggacatgct gcagagcccc      600

ctgacccggc cccggcccgg cccccgctgg ctccggagcc gcaactcgga gctgcgtcag      660

ttgcgtcgcc gctggttcca ccacttcatg agtgactccc agggaccgcc cgccctgggc      720

cccgaggctg ccaggcccgc catccacagc cgaggcacct acattggatg cttcagtgac      780

gatggccacg agaggactct gaaaggagct gtgttttatg acttgagaaa gatgactgtc      840

tcccactgcc aggatgcgtg tgctgagcgg tcctatgtct acgccggctt ggaggccggg      900

gcggagtgtt actgcgggaa ccggctgcca gcggtgagcg tggggctgga agagtgtaac      960

catgagtgca aaggcgagaa gggctctgtg tgcggggctg tggaccggct ctccgtgtac     1020

cgtgtggacg agctgcagcc gggctccagg aagcggcgga ccgccaccta ccgcggatgc     1080

ttccgactgc cagagaacat cacacatgcc ttccccagct ccctgataca ggccaatgtg     1140

accgtgggga cttgctcggg cttttgttcc cagaaagagt tccccttggc cattctcagg     1200

ggctgggaat gctactgtgc ttaccctacc ccccggttca acctgcggga tgccatggac     1260

agctcagtat gtggccagga ccctgaggca cagaggctgg cagaatactg tgaggtctac     1320

cagacacctg tgcaagacac tcgttgtaca gacaggaggt tcctgcctaa caaatccaaa     1380

gtgtttgtgg ctttgtcaag cttcccagga gccgggaaca catgggcacg gcacctcatt     1440

gagcatgcca ctggcttcta tacagggagc tactactttg atggaaccct ctacaacaaa     1500

gggttcaagg gcgaaaagga ccactggcgg agccgacgca ccatctgtgt caaaacccac     1560

gagagtggca ggagggagat tgagatgttt gattcagcca tcctgctaat ccggaaccca     1620

tacaggtccc tggtggcaga attcaacaga aaatgtgccg ggcacctggg atatgcagct     1680

gaccgcaact ggaagagcaa agagtggccg gactttgtca acagctacgc ctcgtggtgg     1740

tcctcgcacg tcctggactg gctcaagtac gggaagcggc tgctggtggt gcactacgag     1800

gagctgcggc gcagcctggt gcccacgtta cgggagatgg tggccttcct caacgtgtct     1860

gtgagcgagg agcggctgct ctgcgtggag aacaacaagg agggcagctt ccggcggcgc     1920

ggccggcgct cccacgaccc tgagcccttc accccggaga tgaaagactt gatcaatggc     1980

tacatccgga cggtggacca agccctgcgt gaccacaact ggacggggct gcccagggag     2040

tatgtgccca gatgataggc ctggcccacg ccgccgcccc cgctgagtga cgcaatcgca     2100

ccacggggct gcgctcccca ctctgatgct caggcccgtg gcctcactgg gacgaacggt     2160

gggtgggggg ctcaccctgg tgctgcctcc cgcacaagga gacctggaca caacagacac     2220

acatcacaag gcgaacacaa atggacacac atacctggcc acgaacccac acctcctcag     2280

acactcagac accactccag gctcatagcc ccgtcttgat gcagagaagc cacccacgtg     2340

gggtgtgcca ggcaccccca gatacaaatg cagccacgca cagacgtaac acacaggtgc     2400

caggccgtgt gctcctggag gctggctggc tgtctctctc acacagatac acgtgcgctc     2460

cctgggatcc gggaggccct gggcttcctg tgtgtagccc tggcatagac ttgctcgtca     2520

gggtgttcga ctctgggatg ctgggccggg cagacattta tgctctgagc agcaaggacc     2580

attgggatgg aggtgggcac aaagactgct gcttccaggg tgtgcggccc tggccgtgtg     2640

tctgacatcc cataaatgtg tgtgtggtgt gactacgggc accacaaact ccgcagcctt     2700

gcctctcttt tctctgtggc tgggctggct gcaccatggg cagggttgag gactgccccc     2760

caccccgccc aagccaatgc agacactgac ctcaagacca gccacaccaa gtctgtgcac     2820

tgcccaccac ccccttcaac ccctcctaca ccatgctccg gggcctgggg cctccttgcc     2880

tggcttcttc ctccagctat cctcagggaa gctggagatt caagtcatgc cccagaagca     2940

aggtgtaagc atgggggcgt ggggaagagg gcaggagctg aagttccagg ggagcccagg     3000

acccctgggg acctgtacac tagcaggatg ggtcttggga gttggcatgg ggagattgta     3060

agggctgtat ctccgcgatt actggtactg gtgctccacc cataggggcc ctgttctctc     3120

tggggtccca cactggggtc atgagagcta gttagtactc agcctgaccc ctaggtctgg     3180

tcctgccagc ctgggatggg ggtcaatgta tgctacacat cttgggctca caagtgaggc     3240

tgtggaggcc aggaggttca agtatggagg gtaggagtgc aacccaggag caacgctcaa     3300

ggtggccgag atgcagggag gattgtggcg atccggttgc acactggcct ctgtggaggt     3360

cagggaggtg ggaaggtggg tgggcctgaa ctcaggcagc ccttcagtgg cttcttcagg     3420

cctaggataa ccctggccag gccccatggt cctgctctgg gtcagctgtc agggagacct     3480

cccttcagcc tgagccaagc tgcattggga ggagaaggca gggtgaggga tctgggagag     3540

caggacgttg agatatcctg accctctgct tcctagcctg atgatgggga acccagagcc     3600

acccgctatg agcacaggcc gggggtggaa ggcccagtag agctgccctt ccccagatgg     3660

aagcttcctc caaccttcag tttggccagt gggtgggttt gggcatctgt gcccctggtg     3720

gcctccaaat ccttcctggg attcccccaa acccacactg atgcgaagct gttcttgacc     3780

ctcccatagc atcaactcag ttcagctcaa agctagaaac accaaggtct ttgaaaatgt     3840

ttattggctc aggatagctt cggcatccaa tctgcgaagg cccctgatgg agctatttct     3900

tcctagtatc aggagcaatt gagacccctc aggagtttcc acactgctgt ggacgggata     3960

gccagggcag acctgcatcc cagagcaagc ctagatcctt gaaagcaatg tcaggcgtgg     4020

cagtggggaa gccatggagg ctgggaaggg caaagtgtgg agagaggagt gaccgggact     4080

ggagccaggg tctggggaga gcaacagcac caggcttttc ctggtagttg gattggtaca     4140

ttcactgctg ccaggtaccc agagatgtca tctctctcca ggtagagcat caccagctcc     4200

tgtggccttg tagatgactc tgtacctcag tgaagagtgc aggcaagtag agtgatgggg     4260

tcagtgtcca tccagtttac gctgagtcag tccatacagc aagacacctg gcacttggca     4320

ggtactcctg gatgttgatg agcaaggaag agcaacggcc ctgtcagctg gcagtggtcc     4380

tcacagcctt catcccaggt ctgcctacgt gggagatctc atcagaaaca ggaacgggga     4440

tctgtctgtg cttgcaggaa agtccatttg tttttctcca agttaggtct catctacagc     4500

tcttagcttc tcagtaaaga ggatactctc ccaaccagcc aaggaataaa agctgatctg     4560

tatgtagggc agaagtgtgg caaatgcatc aggaaccggt tagaacagaa cagagaaacc     4620

ctgactgtct acagattcca actttaatag caagcctgtg gagttacaca aacctgtgtt     4680

aaaacatgta atttttatgg atttcatctc ccgttgtgga tcaatttgga aaaaccaaaa     4740

tatgtaattt taaaaaacta aaacacatcc tggtagtccc agtgatgtgt aaatgagaga     4800

gaagaataga caggcttcca aaccctggga agaaagctgc ttaattatgt gaacatctta     4860

taatgaagtc tcttgcagct aaaattagat tttgagtgca tgaatctgtg ataatgtttg     4920

catatcagaa tgcattctcc ccttaaaagt agcagtagcc acttggttct tagggggccc     4980

caagaggaga ggagaagtgc tgaggttgat gttacgactg caagaattct tgggacacag     5040

gtttgttttc tgctgacttg ctcggaaacc cattggaggt atctgaaatg tgatgactcc     5100

aaaggggttc atttcactat agggagaaat tgattcgtct gacttcctat ttatcaccac     5160

tcaatattgg gtgagttggt ctgaacaagg tggggataaa gtagagtgga aataatgtag     5220

agtcgtcaga ctgaaaggcc aggttgtagt cccagctctt atctgccatc ttggacaaag     5280

cttttcccat ctccagtctc agtttcccat ccataaaatg ggggaagtgg taggtcttgc     5340

tgattgcatc cacattcatt cctccatttc ctttcccagc aaccccccat ttctgtttgg     5400

gaattcatat gatctgccag agcctctcca ggggtggaat acatgtcctg gactaagcca     5460

atgacacctt ccatctttcc agctatggtg actgggttag gtatgatctt gtgagttaag     5520

acaatgaagc cagagggaat ttcaagactt atgggaatgc tgggtagaag ctgttttaat     5580

tcccctgttg aatgtgaaaa aggtagtagt attcctgggt ctttatgatg accaccttgg     5640

gccttgggat catgaccagg aatcacgtga agctgacacc actgaaggga gagttgagag     5700

gcagaaagag atcaagtcct tggtgaaatt gtttaagtac aggatcaagc cttgcttgag     5760

attggcctta cctctggact ttttttgtta tatgagctaa taaattctgt ttattgttta     5820

aaaaaaa                                                               5827


<210>  1149
<211>  2748
<212>  DNA
<213>  homo sapiens

<400>  1149
attttcgcgt ctcctgacga aggggcccga ccgcgccgcg tttcgggagc ggacgtccga       60

gccacggccg aggcccgatt agtccgtccg gcaccgctcg ggcactttcg gaagggaaga      120

ggtggagaac cgacgttcgg gagcattcgg cctcggggac attcggctcg tctcggctcg      180

gcctcgggct gactcggctt ccgccggcgg cgggaacggg cgaaacccgc ggcactaagc      240

tctctctgag aggcagaatt gcgccggccg ccggcgagaa tctgcctaga gccgtccagc      300

cctgtcggcc ggggacgaca gccgcctcag cctgtcagga cagtgaggag agcaggggcc      360

gagtctctcg gaagccctcg tgaggactcg gacctattcg gactgattcg gcttcccact      420

tcggggaact tcgaccctcc tcggttcagg actcggtctc ggctcggcgg cttcgtgcag      480

gttcggctcc tactcgggca gcctctgttc gcctcggctc cgctccgcgg gcggactcgg      540

ctcggctctg ctcggcggct ggctgccttt tcggtcccta ttcgggcggc ggcttcgggc      600

ggcctcggcc cagctcgggc gtcctcttcg ggccccgctt cgggctccgc gaccggcgct      660

tcgggcggtc ccggacggcg ccttcgggaa ggctcggcgg agtccggatg gaggactcgg      720

actcggcggc aaagcagctg ggcctggctg aggcggcggc ggtggcggcc gcggccgctg      780

tggcggcggc ggccgcggcc gcggcaggag gcgaggcgga ggagccggtg ctgagcaggg      840

acgaggactc ggaggaggac gcagactcgg aggcggagcg ggagacgccg cgggtcacgg      900

cagtggcggt gatggcggcg gagcccgggc acatggacat gggcgccgag gccctgcccg      960

gccccgacga ggccgccgct gccgcagcct tcgcagaggt gaccacagtg acagtggcca     1020

acgtgggggc tgctgcagac aatgtcttca ccacgtctgt ggcgaacgcg gcatccatct     1080

caggacatgt tctgtctggt aggacggccc ttcagatcgg ggacagcctg aacaccgaaa     1140

aagcgacact gattgtcgtc cacacagatg ggagcatcgt ggagaccacc gggctgaaag     1200

gcccggcagc tcccctcacc ccaggtcctc agtctcctcc aacccctctg gctcccggcc     1260

aagaaaaagg tggaactaaa tacaactggg acccttctgt gtacgacagt gagctgcccg     1320

tacggtgccg gaacatcagc ggcactctgt acaagaacag gctcggctca ggcggccggg     1380

gacggtgcat caagcagggg gagaactggt acagtcccac cgagtttgag gccatggcag     1440

gaagagccag cagtaaggac tggaaaagaa gcattcgcta cgcgggccga cccttgcagt     1500

gcctcatcca ggatgggatc ttaaaccctc acgctgcctc ttgcacctgt gctgcctgct     1560

gcgacgacat gaccttaagt ggcccagtca ggctttttgt gccttacaaa aggcgcaaga     1620

aggagaatga actgcccaca actcccgtga agaaggactc ccccaagaac atcacattgc     1680

ttccagccac cgcggctacc accttcaccg tgaccccctc gggacagatc acgacctcgg     1740

gggcactgac ctttgaccga gcgtccacgg tagaggccac tgctgtcata tcagagagtc     1800

cggcccaggg cgacgtcttc gcaggggcca cagtccaaga ggccagcgtg cagcccccat     1860

gcagggccag ccaccctgag cctcactacc ccggctatca ggacagctgc cagatcgcac     1920

cgtttccaga agctgcgttg ccaacgtcac atcccaaaat agtgttgaca tccctgcctg     1980

cgctggcggt cccacccccg actcccacca aagcggcacc tcccgcgttg gtcaatgggc     2040

tggagctgtc agagccgcgg agctggctgt acctagaaga gatggtcaac tccttgctca     2100

acacagcgca gcagctgaag acgctgtttg agcaagccaa gcatgccagc acctaccgag     2160

aagctgccac aaaccaggcc aagatccacg ctgacgcaga gcggaaggag cagtcctgcg     2220

ttaactgcgg ccgggaggct atgagcgagt gcaccggctg ccacaaggtc aactactgct     2280

ccaccttctg ccaacgcaag gactggaagg atcaccagca catatgcggc cagtcagcag     2340

ctgtcaccgt ccaggcagac gaagtccacg tggctgaaag cgtgatggag aaggtgaccg     2400

tgtgaggctc catcggccgc cctgggagct ggggcccctc gcactcctgt gaggcttttg     2460

caggtcgaag gcccccctga ggactctggg gggacgttga gaagaggggt gtgggaaggt     2520

aaagaaactt gctggacaag tcattaacac actttaagcg aatggtgccc tgggaagcgc     2580

actccccctg cccgggcccc ctgcccgctc gcggacagat tttttatccc tgggatcatg     2640

agcgtccggt cttgcccaca gggcctgtgc tgcgacgcac atacatacgt gttgtgtctg     2700

tcaataaagt gtaaataagg tctccctgcc ccacaaaaaa aaaaaaaa                  2748


<210>  1150
<211>  5121
<212>  DNA
<213>  homo sapiens

<400>  1150
acaaaggcgc ccgcccgccg cccgccgccc gcgcccgcgc cgccgccatg aagccggggc       60

cgccgcaccg tgccggggcc gcccacgggg ccggcgccgg ggccggggcc gcggccgggc      120

ccggggcccg cgggctgctc ctgccaccgc tgctgctgct gctgctggcg gggcgcgccg      180

cgggggccca gcgctggcgc agtgagaact tcgagagacc cgtggacctg gagggctctg      240

gggatgatga ctcctttccc gatgatgaac tggatgacct ctactcgggg tcgggctcgg      300

gctacttcga gcaggagtcg ggcattgaga cagccatgcg cttcagccca gatgtagccc      360

tggcggtgtc caccacacct gcggtgctgc ccaccacgaa catccagcct gtgggcacac      420

catttgaaga gctcccctct gagcgcccca ccctggagcc agccaccagc cccctggtgg      480

tgacagaagt cccggaagag cccagccaga gagccaccac cgtctccact accatggcta      540

ccactgctgc cacaagcaca ggggacccga ctgtggccac agtgcctgcc acagtggcca      600

ccgccacccc cagcacccct gcagcacccc cttttacggc caccactgct gttataagga      660

ccactggcgt acggaggctt ctgcctctcc cactgaccac agtggctacg gcacgggcca      720

ctacccccga ggcgccctcc ccgcccacca cggcggctgt cttggacacc gaggccccaa      780

cacccaggct ggtcagcaca gctacctccc ggccaagagc ccttcccagg ccggccacca      840

cccaggagcc tgacatccct gagaggagca ccctgcccct ggggaccact gcccctggac      900

ccacagaggt ggctcagacc ccaactccag agaccttcct gaccacaatc cgggatgagc      960

cagaggttcc ggtgagtggg gggcccagtg gagacttcga gctgccagaa gaagagacca     1020

cacaaccaga cacagccaat gaggtggtag ctgtgggagg ggctgcggcc aaggcatcat     1080

ctccacctgg gacactgccc aagggtgccc gcccgggccc tggcctcctg gacaatgcca     1140

tcgactcggg cagctcagct gctcagctgc ctcagaagag tatcctggag cggaaggagg     1200

tgctcgtagc tgtgattgtg ggcggggtgg tgggcgccct ctttgctgcc ttcttggtca     1260

cactgctcat ctatcgtatg aagaaaaagg atgagggcag ctacacgctg gaggaaccca     1320

agcaggcgag cgtcacatac cagaagcctg acaagcagga ggagttctat gcctagtgga     1380

gccacagtgc ctccctgcag cctcaacacc accctgctgt ccagtcccca gcctggcccc     1440

accagcccaa gcctgggact gggcctggaa cctggcccca gttcttctct gccctctctc     1500

ccaaggtctg cccaggctgc cagcctcaca cagatcttcc ccgaggaaga ggggctgctg     1560

ccatctgccc cagactgtgc ccttacgagc tcatctcttg ttcccctcat ccctgccacc     1620

agtctggggc ttcaggacct catgtcagat ggatgggagg aagaaagctc ctgattggct     1680

ggtggtggaa gaaagggtgg ggcttgagat gagcctgagc cctgacttgg cacccacagt     1740

gctcactgag atctcctttt tggggcagag aggcactcag gctggtttcc aggacaaaca     1800

tttggtaaac acagcccttg aaatcatcta gacactgcaa cctcttgctc gtatcccagg     1860

gcctctctct agctgggtga gagggtgtcc cttgtcacca gcctgttttg tcctggtctc     1920

tctggggttg ttgaatctct cctcttgcct gccaagtaca catgtaccca gacttcattt     1980

ctttctgcat cttcccccaa gaaacagctt cctgagggtg ctggggcagc cactggtgag     2040

gaggggctgc tctgatgtcc ctcctatgag gggactctgc acagacacca ttgcccacac     2100

tatcaccata ttttcactca gtcacacaca agacaaaagc atgcaatgac aaaaccatac     2160

gcaatcctga ccgcccagcc aatcaagaca tatcacagaa cacacgcgtc cttccaagaa     2220

tgtttatcct catgcatcac ttacacaccc ccagacacgt actgcaatgc aagtcactag     2280

tcatggtcac atgacagtga cagtgtggcc tcctcctacc ccaaatacac ccacactctg     2340

gcaccacaca cattgtctcc agctttcagg cttactgggg agggtggaat cgagccagaa     2400

caatcagccc atattgggtc cccctaagtt gccccgtcat actcagtccc atgccatggt     2460

gcccacacca accatgcagc cgccaacccc agccagtgtc agacacaatc ccatgtggat     2520

gcacagtctc actccacatg acctgctctc aatgctggag ggaaacaggc aggcccttgc     2580

ctttctcgga aaaagtgtgg ggccacagcc cttttagggc attgcatgca ggtgggcctg     2640

gcttcacccc tacctgcttc ctccccaccg cagctggcag agggggaggt ttggggccag     2700

acccccacta gctgggagcc tgggggctcc tctaaggctg aggaaggaaa tttggcccca     2760

ggttgttggg gggtcttggg tctcccagga cggaaggccc agggcaggga gggggcatgt     2820

ggttgggctc ctttatctcc ctgtgtcccc ttcctgcttt gagctagggg gctgactctg     2880

cctcccagga cacaagtctc caaagtgcct gtgagggcgg gccctccgca ccctctgccc     2940

tctgcctggc aggccaacct cagcccacct gcccagaggc cctccctgtg gacaccccct     3000

cacctatttg gccaaacaat tctggctgca gcttcagggg ccatggctgg aagcagcccc     3060

tgcagatccc tcaggccccg aggtcagggt ttgagggatg agaccaggtg atagtggggg     3120

aggggttact tcctttgtta cctagcaagt agggctattt ccatcggtat tttaaatgtg     3180

gggtcacaga tcttttgggg agggtgtgct tggcaggggg cctcttggag ccaaagggat     3240

gtggtgtgag ttgcgattgg ctggcactca cacccccacc cctcacccac atcccagatt     3300

caagtcagga aggcaggttt tatttcaggg cccttttcaa gatgccctgg cagcagattt     3360

ctgcaggatg aggggtagcg gtgtgtaggc agtgaggggg aggttccagg ggctgtccca     3420

cagcctgtct tttccaggct gggctccatc ttccagtccc aaaaccctcc ttcacagggc     3480

ccagaggctt gtgaggaagc caggtggacc cagccttaga agagtgggca tggggggccc     3540

ctgatatctg gagggggcgg gttggcctca gtcatctttg gagcagaagg gctgggtcct     3600

ggggccacag accacaaggc tcagcctccc taccctgctc cctggggtgc tgctgtcttg     3660

gagagcacag ctctggtgag acggcctggg caggccgagg ctgagaaacc agggaggata     3720

gaggagaaaa gggcttgggc ccccagcccc agaagatgct ggaccccagg tgggagaccc     3780

aacagtgggt gcagtttctc agtagggctg gagccaatgg tgggggtggc cccggcaggc     3840

ctggctcctc acatcccagg ggttggcttc tgatttgggg cttgggctcc aggcactggc     3900

ttctcttctc tgtgtcctta gcatttgaga gaagaggcca ggggccttgt tcatggatcc     3960

ctggacccaa ggcagatgtc caggctttat cctcctgagg atgaggagtc tgaccagccc     4020

aaatctgccc tggccggcct gaccggggca aggcagtcca agagagttca gtgaggacca     4080

gctaggctct cccaggtgca atgtgggtgc agggccctca tgtcccccta cccctgcctg     4140

tgatggagtg ttctgagggg ctttggcatt tgctggaagc acagggagtt ccaaatgaga     4200

gggagcttct gtggcttgag agcctctggg gccttggctg ccagagcacg aggcaggcca     4260

ggacctggag agcccagacc ctgtctccag gaggccagga ggccagatgg gggccttgcc     4320

tgaaagactg gtccccttga tcgctggagg catgtgggtg gcaaccaggg ctgggcaggg     4380

cttagggtgt gtgggccaaa cccccctggg gttggcaaag ccgcctgtca ggcctcctgg     4440

tgggggcccc tggacacagg gagcagaccc tctgcctcat ggggtaggag tggctgcctc     4500

ctgtgttctc tggatttctt ctcccaacaa ctacaaccct ggacttgcct ccccaggcct     4560

cttgcctgta aatagaagcc cgcaaactgt acagatttac agaggcatcg agactgggcc     4620

ctgggagttg ccatctgaga gccgatggcc ccagcatccc ccaggtgcct gcctggcacc     4680

acagtgaccc tggcctcagc gtggcaaatg catgtaaata tttttcgtag gcagcgtggc     4740

tccagagagc cccctgaaga cagtgtccct ccctcctgtg agtcctttct cctgtacaga     4800

acctgcctgg ggtgggtggg ggtctgccat tccctccccc aggccttccc tgccccttct     4860

ctcccctgta acctgtttat taaccatacc tgtcctgagt tcatggccaa aaccttaaat     4920

aagaaaaaca aaagaaaaag acagtggaaa aaagagacca aggcgcctgc cccactgcgg     4980

gtactctcct gttccagcct tgtgaaggaa ctggttttgt ttttgttttt tttttttttt     5040

tttttttttt gtttgtttgt ttttttaaca cttcctgtgc tgtgcccatt tataagagga     5100

aataaaatta agctgaaatg a                                               5121


<210>  1151
<211>  1590
<212>  DNA
<213>  homo sapiens

<400>  1151
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag caggaccatt      120

ctggctgctg tctggacaag aagtcgtagg gggtgagggt ggaagctggg aaacccacag      180

gaggcaacca cactagttta ggtgatgttc tgcaccctga acacccacaa agtggacatg      240

gacaagctcc tggggggcca gatcgggctg gaggacttca tcttcgccca cgtgaagggg      300

cagcgcaagg aggtggaggt gttcaagtcg gaggatgcac tcgggctcac catcacggac      360

aacggggctg gctacgcctt catcaagcgc atcaaggagg gcagcgtgat cgaccacatc      420

cacctcatca gcgtgggcga catgatcgag gccattaacg ggcagagcct gctgggctgc      480

cggcactacg aggtggcccg gctgctcaag gagctgcccc gaggccgtac cttcacgctg      540

aagctcacgg agcctcgcaa ggccttcgac atgatcagcc agcgttcagc gggtggccgc      600

cctggctctg gcccacaact gggcactggc cgagggaccc tgcggctccg atcccggggc      660

cccgccacgg tggaggatct gccctctgcc tttgaagaga aggccattga gaaggtggat      720

gacctgctgg agagttacat gggtatcagg gacacggagc tggcggccac catggtggag      780

ctgggaaagg acaaaaggaa cccggatgag ctggccgagg ccctggacga acggctgggt      840

gactttgcct tccctgacga gttcgtcttt gacgtctggg gcgccattgg ggacgccaag      900

gtcggccgct actaggactg cccccggacc ctgcgatgat gacccgggcg caacctggtg      960

ggggccccca gcagggacac tgacgtcagg acccgagcct ccagcctgag cctagctcag     1020

cagcccaagg acgatggtga ggggaggtgg ggccaggccc cctgccccgc tccaatcggt     1080

accatcccct ccctggttcc cagtctggcc ggggtccccg gcccccctgt gccctgttcc     1140

ccacctacct cagctgggtc aggcacaggg aggggaggga tcagccaaat tgggcggcca     1200

cccccgcctc caccactttc caccatcagc tgccaaactg gtccctctgt ctccctgggg     1260

ccttgggttc tgtttggggg tcatgacctt cctagtttcc tgacgcaggg aatacagggg     1320

agagggttgt ccttcccccc agcaaatgca ataatgccct cacccctcct gagaggagcc     1380

ccctccctgt ggagcctgtt acctccgcat ttgacacgag tctgctgtga accccgcaac     1440

ctcctcccca cctcccatct ctccttccag gcccatccct ggcccagagc aggagggagg     1500

gagggacgat ggcggtgggt ttttgtatct gaatttgctg tcttgaacat aaagaatcta     1560

tctgctgttg gaaaaaaaaa aaaaaaaaaa                                      1590


<210>  1152
<211>  4307
<212>  DNA
<213>  homo sapiens

<400>  1152
ccgcggccgg gccgagccgc aggcgctgcc cgagccgcgg gcgctggagc ggctgtcggc       60

gcggtggcag gcgggagcca ggagtccggg gctcgggcgg gcggagcgca gcgcggggac      120

gcggcggagc gggccccgcg gctcggcggg ggccggcaga caggtgtgcc ggcggcgggc      180

ggctcgcgct caggcggctc caggccgggc ccggggtccg gagcggggag ccgggagccg      240

agcgaggacc cggcgcccgc agtccagtct tggccgcgcc cgtgctcggc ttggccgcgg      300

ggtgcgggga ccacggcccg gccgggccac ccgaagccta gtgctgggcc gggccgggcc      360

ggggtgggtg ggggcccgcc cggcccgccc atgggctcag gatgccggtg cggaggggcc      420

acgtcgcgcc gcagaacacc ttcctggaca ccatcatccg caagtttgag ggccagagcc      480

gtaagttcat catcgccaac gctcgggtgg agaactgcgc cgtcatctac tgcaacgacg      540

gcttctgcga gctgtgcggc tactcgcggg ccgaggtgat gcagcgaccc tgcacctgcg      600

acttcctgca cgggccgcgc acgcagcgcc gcgctgccgc gcagatcgcg caggcactgc      660

tgggcgccga ggagcgcaaa gtggaaatcg ccttctaccg gaaagatggg agctgcttcc      720

tatgtctggt ggatgtggtg cccgtgaaga acgaggatgg ggctgtcatc atgttcatcc      780

tcaatttcga ggtggtgatg gagaaggaca tggtggggtc cccggctcat gacaccaacc      840

accggggccc ccccaccagc tggctggccc caggccgcgc caagaccttc cgcctgaagc      900

tgcccgcgct gctggcgctg acggcccggg agtcgtcggt gcggtcgggc ggcgcgggcg      960

gcgcgggcgc cccgggggcc gtggtggtgg acgtggacct gacgcccgcg gcacccagca     1020

gcgagtcgct ggccctggac gaagtgacag ccatggacaa ccacgtggca gggctcgggc     1080

ccgcggagga gcggcgtgcg ctggtgggtc ccggctctcc gccccgcagc gcgcccggcc     1140

agctcccatc gccccgggcg cacagcctca accccgacgc ctcgggctcc agctgcagcc     1200

tggcccggac gcgctcccga gaaagctgcg ccagcgtgcg ccgcgcctcg tcggccgacg     1260

acatcgaggc catgcgcgcc ggggtgctgc ccccgccacc gcgccacgcc agcaccgggg     1320

ccatgcaccc actgcgcagc ggcttgctca actccacctc ggactccgac ctcgtgcgct     1380

accgcaccat tagcaagatt ccccaaatca ccctcaactt tgtggacctc aagggcgacc     1440

ccttcttggc ttcgcccacc agtgaccgtg agatcatagc acctaagata aaggagcgaa     1500

cccacaatgt cactgagaag gtcacccagg tcctgtccct gggcgccgac gtgctgcctg     1560

agtacaagct gcaggcaccg cgcatccacc gctggaccat cctgcattac agccccttca     1620

aggccgtgtg ggactggctc atcctgctgc tggtcatcta cacggctgtc ttcacaccct     1680

actcggctgc cttcctgctg aaggagacgg aagaaggccc gcctgctacc gagtgtggct     1740

acgcctgcca gccgctggct gtggtggacc tcatcgtgga catcatgttc attgtggaca     1800

tcctcatcaa cttccgcacc acctacgtca atgccaacga ggaggtggtc agccaccccg     1860

gccgcatcgc cgtccactac ttcaagggct ggttcctcat cgacatggtg gccgccatcc     1920

ccttcgacct gctcatcttc ggctctggct ctgaggagct gatcgggctg ctgaagactg     1980

cgcggctgct gcggctggtg cgcgtggcgc ggaagctgga tcgctactca gagtacggcg     2040

cggccgtgct gttcttgctc atgtgcacct ttgcgctcat cgcgcactgg ctagcctgca     2100

tctggtacgc catcggcaac atggagcagc cacacatgga ctcacgcatc ggctggctgc     2160

acaacctggg cgaccagata ggcaaaccct acaacagcag cggcctgggc ggcccctcca     2220

tcaaggacaa gtatgtgacg gcgctctact tcaccttcag cagcctcacc agtgtgggct     2280

tcggcaacgt ctctcccaac accaactcag agaagatctt ctccatctgc gtcatgctca     2340

ttggctccct catgtatgct agcatcttcg gcaacgtgtc ggccatcatc cagcggctgt     2400

actcgggcac agcccgctac cacacacaga tgctgcgggt gcgggagttc atccgcttcc     2460

accagatccc caatcccctg cgccagcgcc tcgaggagta cttccagcac gcctggtcct     2520

acaccaacgg catcgacatg aacgcggtgc tgaagggctt ccctgagtgc ctgcaggctg     2580

acatctgcct gcacctgaac cgctcactgc tgcagcactg caaacccttc cgaggggcca     2640

ccaagggctg ccttcgggcc ctggccatga agttcaagac cacacatgca ccgccagggg     2700

acacactggt gcatgctggg gacctgctca ccgccctgta cttcatctcc cggggctcca     2760

tcgagatcct gcggggcgac gtcgtcgtgg ccatcctggg gaagaatgac atctttgggg     2820

agcctctgaa cctgtatgca aggcctggca agtcgaacgg ggatgtgcgg gccctcacct     2880

actgtgacct acacaagatc catcgggacg acctgctgga ggtgctggac atgtaccctg     2940

agttctccga ccacttctgg tccagcctgg agatcacctt caacctgcga gataccaaca     3000

tgatcccggg ctcccccggc agtacggagt tagagggtgg cttcagtcgg caacgcaagc     3060

gcaagttgtc cttccgcagg cgcacggaca aggacacgga gcagccaggg gaggtgtcgg     3120

ccttggggcc gggccgggcg ggggcagggc cgagtagccg gggccggccg ggggggccgt     3180

ggggggagag cccgtccagt ggcccctcca gccctgagag cagtgaggat gagggcccag     3240

gccgcagctc cagccccctc cgcctggtgc ccttctccag ccccaggccc cccggagagc     3300

cgccgggtgg ggagcccctg atggaggact gcgagaagag cagcgacact tgcaaccccc     3360

tgtcaggcgc cttctcagga gtgtccaaca ttttcagctt ctggggggac agtcggggcc     3420

gccagtacca ggagctccct cgatgccccg cccccacccc cagcctcctc aacatccccc     3480

tctccagccc gggtcggcgg ccccggggcg acgtggagag caggctggat gccctccagc     3540

gccagctcaa caggctggag acccggctga gtgcagacat ggccactgtc ctgcagctgc     3600

tacagaggca gatgacgctg gtcccgcccg cctacagtgc tgtgaccacc ccggggcctg     3660

gccccacttc cacatccccg ctgttgcccg tcagccccct ccccaccctc accttggact     3720

cgctttctca ggtttcccag ttcatggcgt gtgaggagct gcccccgggg gccccagagc     3780

ttccccaaga aggccccaca cgacgcctct ccctaccggg ccagctgggg gccctcacct     3840

cccagcccct gcacagacac ggctcggacc cgggcagtta gtggggctgc ccagtgtgga     3900

cacgtggctc acccagggat caaggcgctg ctgggccgct ccccttggag gccctgctca     3960

ggaggccctg accgtggaag gggagaggaa ctcgaaagca cagctcctcc cccagccctt     4020

gggaccatct tctcctgcag tcccctgggc cccagtgaga ggggcagggg cagggccggc     4080

agtaggtggg gcctgtggtc cccccactgc cctgagggca ttagctggtc taactgcccg     4140

gaggcacccg gccctgggcc ttaggcacct caaggacttt tctgctattt actgctctta     4200

ttgttaagga taataattaa ggatcatatg aataattaat gaagatgctg atgactatga     4260

ataataaata attatcctga ggagactcca aaaaaaaaaa aaaaaaa                   4307


<210>  1153
<211>  7355
<212>  DNA
<213>  homo sapiens

<400>  1153
agtctgcggg cctccggggc agcggcgagg ccggagcgtc gcggcggaga ggacgagacc       60

gggacaagac cagggcagga gggagccggc cagccgcgag aaccccgcac gcccggcaag      120

atgctgtcct ggcggctgca gacgggcccc gagaaggccg agctccagga gctcaacgcc      180

cggctctatg actacgtgtg tcgggtgcgg gagctggagc gcgaaaacct actcctggag      240

gaggagctgc gcggccggcg cgggcgagag ggcctgtggg ccgaggggca ggcccgctgc      300

gccgaggagg cgcgcagctt gcggcagcag ctggacgagc tgagctgggc cactgcgctg      360

gcggagggcg agcgggacgc tctgcggcgc gagctgcggg agctgcagcg cctggatgcg      420

gaggagcgcg ccgcccgcgg ccgcctggac gccgagctgg gtgcgcagca gcgcgagctg      480

caggaggcgc tgggcgcgcg cgccgccctc gaggcgctgc tgggccggct gcaggccgag      540

cgccgaggcc tcgacgcggc ccacgaacgc gacgtgaggg agctgcgcgc gcgcgccgcc      600

agccttacca tgcatttccg cgcccgcgcc accggccccg ccgcgccgcc gccacgcctg      660

cgggaggtgc acgacagcta cgcactgctg gtggccgagt cgtggcggga gacggtgcag      720

ctgtacgagg acgaggtgcg cgagctggag gaggcgctgc ggcgcggcca ggagagcaga      780

ctccaggcgg aggaagagac gcggctgtgc gcgcaggagg cagaggcgct gcggcgcgag      840

gcgctcgggt tggagcagct gcgcgcgcgg ctggaggacg cgctgctgcg gatgcgcgag      900

gagtacggga tacaggccga ggagcggcag agagtgattg actgcctgga ggatgagaag      960

gcaaccctca ccttggccat ggctgactgg ctgcgggact atcaggacct cctgcaggtg     1020

aagaccggcc tcagtctgga ggtggcgacc taccgggcct tattggaagg agaaagtaat     1080

ccagagatag tgatctgggc tgagcacgtt gaaaacatgc cgtcagaatt cagaaacaaa     1140

tcctatcact ataccgactc actactacag agggaaaatg aaaggaatct attttcaagg     1200

cagaaagcac ctttggcaag tttcaatcac agctcggcac tgtattctaa cctgtcaggg     1260

caccgtggat ctcagacggg cacatctatt ggaggtgatg ccagaagagg cttcttgggc     1320

tcgggatatt cttcctcggc cactacccag caggaaaact catacggaaa agccgtcagc     1380

agtcaaacca acgtcagaac tttctctcca acctatggcc ttttaagaaa tactgaggct     1440

caagtgaaaa cattccctga cagaccaaaa gccggagata caagggaggt ccccgtttac     1500

ataggtgaag attccacaat tgcccgcgag tcgtaccggg atcgccgaga caaggtggca     1560

gcaggtgctt cggaaagcac acggtcaaat gagaggaccg tcattctggg aaagaaaaca     1620

gaagtgaaag ccacgaggga gcaagaaaga aacagaccag aaaccatccg aacaaagcca     1680

gaagagaaaa tgttcgattc taaagagaag gcttccgagg agagaaacct aagatgggaa     1740

gaattgacaa agttagataa ggaagcgaga cagagagaaa gccagcagat gaaggagaag     1800

gctaaggaga aggactcacc gaaggagaag agcgtgcgag agagagaggt gccgattagt     1860

ctagaagtat cccaggacag aagagcagag gtgtccccga aaggtttgca gacgcctgtg     1920

aaggatgctg gtggtgggac cggtagagag gcagaagcaa gagagctacg gttcaggttg     1980

ggcaccagtg atgccactgg ttctctgcaa ggcgattcca tgacagaaac cgtagcagaa     2040

aacatcgtta ccagtatcct gaagcagttc actcagtctc cagagacaga agcatctgct     2100

gattcttttc cagacacaaa agtcacttac gtggacagga aagagcttcc tggggaaagg     2160

aaaacaaaga ctgaaatagt tgtggagtct aaactgactg aggatgttga tgtttccgat     2220

gaagctggcc tggactacct tttaagcaag gatattaagg aagtggggct gaaaggcaag     2280

tcagccgagc agatgatagg agacatcatc aacctcggcc tgaaagggag ggaggggaga     2340

gcaaaggtcg tcaacgtgga gatcgtggag gagcccgtga gttatgtcag cggggagaag     2400

ccggaggagt tttccgtccc attcaaagtg gaggaggtcg aagatgtgtc gccaggcccc     2460

tgggggttgg ttaaggagga ggaaggttat ggagaaagcg atgtcacatt ctcagttaat     2520

cagcatcgaa ggaccaagca gcctcaggag aacacgactc acgtggaaga agtgacagag     2580

gcaggtgatt cagagggcga gcagagttat tttgtgtcca ctccagatga acaccccggg     2640

gggcacgaca gagatgacgg ctcggtgtac gggcagatcc acatcgagga ggaatccacc     2700

atcaggtact cttggcagga tgaaatcgtg caggggactc gaaggaggac acagaaggac     2760

ggtgcagtgg gcgagaaggt tgtgaagccc ttggatgtcc cagcgccctc tctggagggg     2820

gacctgggtt ccactcactg gaaagaacaa gctagaagcg gtgaatttca tgccgaaccc     2880

acagtcattg aaaaagaaat taaaataccc cacgaattcc acacctccat gaagggcatc     2940

tcctccaagg agccccggca gcagctggtg gaggtcatcg ggcagctgga ggaaaccctt     3000

cccgagcgca tgagggagga gctgtccgcc ctcaccagag aggggcaggg tgggccgggg     3060

agcgtttccg tggatgtcaa gaaggtccag ggtgctggtg gcagttccgt gaccctggtt     3120

gctgaagtca acgtctcaca aactgtggat gccgatcggt tagacctgga ggagctgagc     3180

aaagatgagg ccagtgagat ggagaaggct gtggagtcgg tggttcggga gagcctgagc     3240

aggcaacgca gcccagcgcc tggcagccca gatgaggaag gtggagcgga ggccccggct     3300

gctggcattc gctttaggcg ttgggccacc cgggagctgt acatcccttc aggcgagagc     3360

gaggttgctg gtggggcctc tcacagctcg ggacagcgca ctccccaggg cccagtgtcg     3420

gccactgtgg aggtcagcag ccccacaggc tttgcccagt cacaggtgct ggaggatgtg     3480

agccaggctg caaggcacat aaaactcggc ccctctgaag tctggaggac tgagcgaatg     3540

tcatatgaag gacccactgc agaagtggtg gaggtaagtg cgggaggtga cctaagtcag     3600

gcagcgagcc cgaccggagc cagccggtct gtgaggcatg tcacgctggg tcccggtcaa     3660

agtccactgt ccagagaagt catcttccta ggccctgccc ctgcctgtcc agaggcatgg     3720

ggctcgccag aacctggccc agcagagtct tctgcagata tggacggatc agggaggcac     3780

agcacatttg gctgcagaca atttcatgct gaaaaggaga ttatttttca gggccccatt     3840

tctgctgcag ggaaggttgg tgattatttt gcaacagaag agtcagtggg tacccagact     3900

tctgtcaggc aactccagtt aggccctaaa gaagggttca gtgggcaaat ccagttcaca     3960

gctccacttt cagacaaggt ggagttgggt gtcataggag attctgtaca catggaaggg     4020

ttgccaggga gcagcacatc catcaggcac atcagcattg ggcctcagag gcatcagacc     4080

acccagcaga tagtttacca tgggctggtt ccccaactgg gggaatctgg tgactcagag     4140

agcactgtgc acggagaggg ctcagcagat gtgcaccagg ccactcacag tcatacctcg     4200

ggtagacaaa ccgttatgac tgaaaagagc accttccaaa gtgtcgtttc tgaatctccc     4260

caggaggata gtgcagagga cacatcaggg gcagaaatga catcgggtgt tagcagatcc     4320

tttaggcaca ttcgactagg tcctacagaa acggaaacct ctgaacacat tgccatccgt     4380

ggacccgtgt ccagaacatt tgtgcttgct ggttcagcgg actcccctga gctaggcaag     4440

ttagcagaca gcagcagaac gctaaggcac attgcaccag ggcccaaaga aacttcgttt     4500

acctttcaga tggatgtgag taacgtagag gcgatccgca gccggacaca ggaagcggga     4560

gctctcggtg tgtctgaccg tggttcctgg agagacgcgg acagtaggaa tgaccaggca     4620

gttggtgtga gctttaaggc ctctgctggg gaaggagacc aggcccacag agaacagggc     4680

aaggagcagg ccatgtttga taagaaggtg cagctccaga gaatggtaga ccaaaggtcg     4740

gtgatttcag atgaaaagaa agttgccctc ctctatctag acaatgagga ggaggagaat     4800

gatgggcatt ggttttaata agcagaaaca ttttgtttta atggcagcct gttggcgacg     4860

tgccaacatc caaaggcctt aacttatttt aagaggccga gggagtctat gaaaatctcc     4920

ccttttttac ttttttaaag agtactcccg gcatggtcaa tttcctttat agttaatccg     4980

taaaggtttc cagttaattc atgccttaaa aggcactgca attttatttt tgagttggga     5040

cttttacaaa acactttttt ccctggagtc ttctctccac ttctggagat gaatttctat     5100

gttttgcacc tggtcacaga catggcttgc atctgtttga aactacaatt aattatagat     5160

gtcaaaacat taaccagatt aaagtaatat atttaagagt aaattttgct tgcatgtgct     5220

aatatgaaat aacagactaa cattttaggg gaaaaataaa tacaatttag actctaaaaa     5280

gtcttttcaa aaagaaatgg gaaataggca gactgtttat gttaaaaaaa ttcttgctaa     5340

atgatttcat ctttaggaaa aaattacttg ccatatagag ctaaattcat cttaagactt     5400

gaatgaattg ctttctatgt acagaacttt aaacaatata gtatttatgg cgaggacagc     5460

tgtagtctgt tgtgatattt cacattctat ttgcacaggt tccctggcac tggtagggta     5520

gatgattatt gggaatcgct tacagtacca tttcattttt tggcactagg tcattaagta     5580

gcacacagtc tgaatgccct tttctggagt ggccagttcc tatcagactg tgcagacttg     5640

cgcttctctg caccttatcc cttagcaccc aaacatttaa tttcactggt gggaggtaga     5700

ccttgaagac aatgaagaga atgccgatac tcagactgca gctggaccgg caagctggct     5760

gtgtacagga aaattggaag cacacagtgg actgtgcctc ttaaagatgc ctttcccaac     5820

cctccattca tgggatgcag gtctttctga gctcaagggt gaaagatgaa tacaataaca     5880

accatgaacc cacctcacgg aagctttttt tgcactttga acagaagtca ttgcagttgg     5940

ggtgttttgt ccagggaaac agtttattaa atagaaggat gttttgggga aggaactgga     6000

tatctctcct gcagcccagc accgagatac ccaggacggg cctggggggc gagaaaggcc     6060

cccatgctca tgggccgcgg agtgtggacc tgtagatagg caccaccgag tttaagatac     6120

tgggatgagc atgcttcatt ggattcattt tattttacac gtcagtattg ttttaaagtt     6180

tctgtctgta aagtgtagca tcatatataa aaagagtttc gctagcagcg catttttttt     6240

agttcaggct agcttctttc acataatgct gtctcagctg tatttccagt aacacagcat     6300

catcgcactg actgtggcgc actggggaat aacagtctga gctagcacca ccctcagcca     6360

ggctacaacg acagcactgg agggtcttcc ctctcagatt cacctggagg ccctcagacc     6420

cccagggtgc acgtctcccc aggtcctggg agtggctacc gcaggtagtt tctggagagc     6480

acgttttctt cattgataag tggaggagaa atgcagcaca gctttcaaga tactatttta     6540

aaaacaccat gaatcagata gggaaagaaa gttgattgga atagcaagtt taaacctttg     6600

ttgtccatct gccaaatgaa ctagtgattg tcagactggt atggaggtga ctgctttgta     6660

aggttttgtc gtttctaata cagacagaga tgtgctgatt ttgttttagc tgtaacaggt     6720

aatggttttt ggatagatga ttgactggtg agaatttggt caaggtgaca gcctcctgtc     6780

tgatgacagg acagactggt ggtgaggagt ctaagtgggc tcagtttgat gtcagtgtct     6840

gggctcatga cttgtaaatg gaagctgatg tgaacaggta attaatatta tgacccactt     6900

ctatttactt tgggaaatat cttggatctt aattatcatc tgcaagtttc aagaagtatt     6960

ctgccaaaag tatttacaag tatggactca tgagctattg ttggttgcta aatgtgaatc     7020

acgcgggagt gagtgtgccc ttcacactgt gacattgtga cattgtgaca agctccatgt     7080

cctttaaaat cagtcactct gcacacaaga gaaatcaact tcgtggttgg atggggccgg     7140

aacacaacca gtctttttgt atttattgtt actgagacaa aacagtactc actgagtgtt     7200

tttcagtttc ctactggtgg ttttgatatt gtttgtttaa gatgtatatt tagaatgaca     7260

tcatctaaga agctgatttt gctaaactcc tgttccctac aatgggaaat gtcacaagaa     7320

tgtgcaaaaa taaaaatctg aggaaaaaac ccaca                                7355


<210>  1154
<211>  8513
<212>  DNA
<213>  homo sapiens

<400>  1154
ggcggcggcg gcggcggagc caggacccag acatctggga ctgttgttct ctcgcggcgc       60

gaccgcctca gtcacttcgc ccagagaccc ggacctggtc cgctggggag caggcggcca      120

taaaccccct ctctcccggt tccctgacgc cgcggcagga gctgttacaa acaccctgcg      180

gttggtctcc gatgcccttc agtgaggtgg ggacgcctgg accctggtga gcgaacccca      240

agccaccccc caccccaact cagtgtcttc gccggccccc ggcccgtacg cctgtctggt      300

cgccatggct gaaaacacag agggggatct gaactccaac ctgctccacg ccccctacca      360

caccggggac cctcagctgg acacggccat cgggcagtgg ctccgctggg ataagaatcc      420

caaaacaaaa gagcagattg aaaacctgtt acggaatggg atgaacaagg agctgcgaga      480

tcgtctttgt tgccgaatga cttttgggac tgcaggactt cgttctgcca tgggggcagg      540

gttttgctat attaatgacc ttacagtaat acagtcaaca caggggatgt acaaatacct      600

tgagagatgt ttctcagact tcaagcagag aggctttgtg gttgggtatg acactcgggg      660

tcaagtaact agcagctgca gcagccagag gcttgctaaa ctcactgctg cagtcttgct      720

ggccaaagat gttcctgtgt accttttttc aagatatgtt cctacacctt ttgtaccata      780

tgcagttcag aagctcaaag cagttgcagg tgtgatgatt actgcctctc acaaccgcaa      840

ggaagacaat ggatacaagg tttactggga aactggtgct cagatcacat ctcctcatga      900

taaagaaatt ctaaaatgta tagaagaatg tgtggaaccc tggaatggtt cctggaatga      960

taatttagtg gataccagcc cgctgaagag agaccctctg caggacattt gcaggagata     1020

catggaagat ctgaaaaaga tctgttttta cagggagtta aactcgaaga ccaccttgaa     1080

atttgtgcac acatcttttc atggggtcgg acatgactat gtgcagttgg cttttaaagt     1140

gtttggtttt aagcctccaa ttccagtacc agaacaaaaa gatcctgatc cagacttttc     1200

taccgttaaa tgtccaaatc ctgaagaagg agaatctgtg ctggaacttt ccttgagact     1260

ggcagagaaa gaaaatgccc gggtagtgct agccacagat cctgatgcag acagactggc     1320

agcagcagaa cttcaggaga atggttgttg gaaagttttc acagggaatg agttggcagc     1380

tttgtttgga tggtggatgt ttgattgctg gaagaaaaat aaatcaagaa atgctgatgt     1440

gaagaacgtt tatatgttag ccaccacagt ctcttctaaa attctgaagg caattgcact     1500

taaagaagga tttcattttg aagaaacatt accaggtttt aaatggattg gaagtaggat     1560

aatagacctc ctggaaaatg ggaaagaagt cctttttgca tttgaagagt ctattggttt     1620

tctctgtgga acttcagttt tggataaaga tggggtgagt gcagctgttg tggttgctga     1680

gatggcatct tacctggaaa ccatgaatat aacattgaaa cagcaactgg ttaaggttta     1740

tgaaaaatat ggttatcata tttcaaaaac ttcctatttc ttgtgttatg aaccacctac     1800

catcaaaagt atatttgaaa ggcttcgtaa ttttgattct ccaaaagaat atccaaaatt     1860

ttgtggaaca tttgctatat tgcatgtacg ggacgttacc actggatatg acagtagcca     1920

gcctaataag aaatcagtgc tgcctgtgag taaaaacagc caaatgatta catttacttt     1980

tcaaaatggc tgtgttgcta cccttcggac aagtggaaca gaaccaaaga taaagtatta     2040

tgcagagatg tgtgcgtcac ctgaccagag tgacactgct ttactggagg aagaactgaa     2100

gaaactcatt gatgctctga tagagaattt tcttcagcct agtaagaatg gactgatctg     2160

gcgttctgtt taggggtaca ccaatatgtc atgacactgt gtgggcatat ggaacagagc     2220

aaccgagaac tgcatacatt gaaccttgtg ttagcattct ctctctatct catctggccg     2280

agtatctttt tccttttatt ttctttcttt ttggtcaact ggctagacta aacaaagtat     2340

aagtttgaaa tgaaatggtc tagagggaaa tgattcaaat tttttcataa ttcaaacaaa     2400

agttattaca ctaaaagtat tatagtaacg tattgtcctt ccgttaacag aaacatcaca     2460

attcaaaagt gagttttctt attatagtgt gattaagcct agttctgtat ctcgtaattg     2520

tgtatagcat ggtaaaagaa aaaaaaaaag acaggtaaat gttatataat tgtagggtta     2580

gttaaggaaa ttagtccata aaattggcaa gaaaatggta ctttccttga ttgttatgaa     2640

aaagtgtcat tgtgacatca caggtattaa tttacaaatt agagtatttg aaataggata     2700

tttagcattt ctgtagttta gaacagatgt tacagtgtgt ggttttggca tgtctgtttc     2760

aggtgccctt ggtgcagtat aaatttactg tatgtattta aaattctgat gtttactgaa     2820

cataaaacaa tagtggcaac actcctattg gctttgttct tatcaaattt ctcagtgcct     2880

tctcagggtc tggtgtgaac agaaaaaaca gtgttcctgc atttaccata atttaatcag     2940

tcaatttgca gatagctaag gaaaatcttc caaaatctgt aggtgcttcc tctatatcaa     3000

gtgagtttgc tgattttaaa atcttaggaa tataaataaa gatcttaata aaagcaagct     3060

taatgtagtt aaggatcttc atattagaat tgtgtcattt atcaaacctt ttattacaga     3120

aaaaaatctg aactgagaaa ggagctctga atttatttga cagtctaact tttgaattac     3180

atttttgtaa gtagatttat tcttttattt tatgaagtaa tgttaatttt actaagaata     3240

aaacatccaa attttaagta ttatgaaata ctaaaactac atgttttaaa acagaggtcc     3300

agtttattct aacatcttgc tgacttctgt agaatttctg attgcatgac tattatttat     3360

cttcttttag tgtagaaaat aattttttac aaaaagtcac ttttgggctg ggcgcagtgg     3420

ctcacgcctg taatcccagc actttgggag gctgaggcag gtggatcaca atgtcaggag     3480

tttgagacta gcctggccaa tatggtgaaa ccctgtctct actaaaaata caaaaattag     3540

ccgggtgtgg tggtgggcac ctgtagtccc agctactcgg gaggctgagg caggagaatt     3600

gcttgaacct aggaggctga gattgcagtg agccgaaatc acgccactac actccagcct     3660

gggcaacaga gggagactcc atctcaaaaa aaaaaaaagt cacttttggc taatcatgca     3720

gtcttctgaa aaggtttaat agagaaatgc tgtttaggct gggcttggtg gctcacatct     3780

gtaataccag cgctttggga ggctgaggca ggaggattgc ttgaggccag gagtttaagt     3840

tacagaacta tgatcacact gccgcactga agcctggatg acagagtgag accttatctc     3900

aaaaaaaaaa aaaaaaagag agagagagag aaaaagaaat gctgtgttta atcttcttaa     3960

aatgtatctt gtcctacata gttctcagaa tacatatggg gtatagttag gagataacaa     4020

taacaagacc taaacaaatt gcttatggga gatagcactg taattagaga atttatttca     4080

tataaaataa taatataaag tttgaactga ttagaatgtt ccttaaatca tggtttcgtt     4140

tgttgcagct gtcagctaac atttggttga gctcatataa tccaaaccta attgtccaac     4200

tattgtattg ccactattgt taatttgttc cttccttact ttcttattgt tggatcttat     4260

atgactgtat gactgtagat aatagacagc tagctaaatg tagagcacca tttttctcaa     4320

tgagtttgtt ttcaaaggct ttgcactgga gaagatatgt gtagaatttt tgttttattt     4380

ttaaaatgtg taaaacatct tttgttttat atgcttttaa gaatgtagat tgtaatttag     4440

gaaatggcat atattctgca aagtggtata atgttgtata tatgaaaaac aggtatattt     4500

ggtttagttc tgtgtttcag tgactgataa acaaaaatga agctaaaatg aatcaacggc     4560

tcattcatag ttactaaagc catgtcatga ctgtcattct attatgaaga aaacagtttt     4620

atttgagtgc tttaatataa tgcaacattt aagtcatctt aaggtgaaaa gttattgaag     4680

tgttcttctc tcaagttaac aaaattttac aaatgttcct gaagtgtatc gattgaggga     4740

attattttat tctagcctgt catgagtctg tctgagcatg atacttaaca tgaacttgat     4800

gtagtaggtg cacatttgcc taacaggata aattcagtga tagcccaagc tggtcaggag     4860

agacagaagt gctggctagg aggtctcagc ctcgggcact acaatgttta tctttttctt     4920

tttgaacaat attgtgaaaa tgattgcatt ctcattgagc atgaaagtca aaactggaat     4980

tttctaaagc tttggagaaa aggagagaat tagtagggca agatcaaagc atacattgga     5040

aataaacagt agaaataagc aaacaatata aagagacacg ggaaatgctt ctcgtgaagg     5100

gcaaatgtaa caccataaca gtagggaata aactgtgtcc cacctgttta cttgtgttta     5160

tttgttgtta tgatgagtat gcacctacca ttttccttta ttgtgatcac taaaatgagg     5220

ccaaggttta ggaggtgaga aaaagtatcc cttttacgga ttcagttcct gctaggatgt     5280

tgtatcagaa tcatgtgaga actcaggaag aggtagagca gaaataaaaa ggaagaaaat     5340

gtagattaga aaataagact tctgagaaaa agttcaagga ataaagattg tttgactctg     5400

gagaggagaa agctgttgag atagtttgct aagtttgcta ataaagcttt attgagtctt     5460

ttattgaagg gttcaaagta agaaatacta tgccatagtg ttctccatct ctagtgaaga     5520

cagaaccaga gggaataagg atcttttttt taaagacagc atggaaagtt taagatttag     5580

gaacttcttg agaaatcttc ataatatctt ctattcaaaa tctttttttt atttttaagg     5640

gaataaaaat tttaaaaatt aagagatata cagatgactt tttaagggtc cttctttcca     5700

gcacattttt tttaaaaact caggttagaa caaaaatgtc ataaagggca ctaaaagtaa     5760

catttgggtt tcactccata tctagaagaa tttagctcac aaaacaattt ttgtgtgttt     5820

tgagtaactg atgcataagt gcaatgaata attttcctgc ttcactgtta tttttaattt     5880

aacctggcaa attaagtgag acttgaacaa aattttgttc atcttgaaga atgtatagtg     5940

gcttaggtta tttgaggttt tcgttttgaa tatatatgtt gttattttga tgtagatacg     6000

ttagcagatg gagaggttct aagagattgg atactttgga atgtctttat ataggaaata     6060

gacctcccat ttcttaagca agttgcttct ggaattgatg caacagggat attagctgta     6120

gtttaatgga taagttgttc tatgagctgc tgctatcagt acttttttcc acattttcca     6180

ttgatatttg tgatgcttga aaaatccaaa cttcacttgg atacatttaa ttttatgcct     6240

ttttctctct acctcccact tttcctaggc acccttgcac attttgttac tgtgaaggac     6300

tattgccctg ttacctcact gataagaaat ctcaactgta ttcattcaga atgctttaag     6360

cttagtcata aactacattt gcctatggac ctttggttat tttgttaatg ttgtcattat     6420

atttaagact tattgtagga agtaatttta aatctatttc ataacctgtt ttgatctgtc     6480

tgcatactgc tatatgttaa tttattacgg ccttttacaa ttcacttgtc atctgagatt     6540

gttctagaaa ctgatgagga aagagtcgta ctaaccaaaa tgaatgggca attgacataa     6600

cattctattt caggtttcct tgtacttggg gagccaaagc acaagatcta aggaaatctt     6660

attcacattt gtccctcaga gcatcttacc ctaagccata gaggtataaa tagtaagatg     6720

agaattgctc attgtctgac tccttgcaca gcatgaattt aattctagtt ggaaacaaag     6780

ttagtgttga ctactggtta ccttaaagta ttcaccatac tatatattta ttagaccatc     6840

tttcctcttt gtttattcaa gactatgtac ttataaaaga gaacctataa gaatgtgtag     6900

agtgaccaaa tagggacaaa gtgacatacc tagagtttgc tgctcaaatt tttccactag     6960

cgtaacccta aagcagaggg gcatgatgaa gggggaaggg gttctgagag caaaatcaga     7020

atcagcctac cactgacatg aagtgtgttc tgtctttaaa atgtaagtga attttgcatt     7080

ctttataata aaacttttaa tataaaaatg atatgtttaa tctttactga aacttatgcc     7140

accacaaagg agcaccatgt tcatcacgtg gctgctcagt tttctccccc agtgccctca     7200

cccccagtgg aggcaagtcc ttgagctaca cacactggct gtagtgcaag atatataaac     7260

ataggccggg ctcggtggct catgcctgta atcctagcac tttgggaggc cgaagcaggt     7320

ggatcatctg aggtcgggag attgagacta gcctgaccga catggagaaa ccctgtgtcc     7380

actaaaaata caaaattagc cgggtgtggt ggcacatgcc tgtaatccca gctactcggg     7440

aggctgaggc aggagaatca cttgaaccca ggaggtggag gttgtggtga gccaagatcg     7500

cgccgttgca ctccagcctg ggcaacaaga gtgaaactcc atctcaaaaa aaaaaaaaaa     7560

agatatataa acatagaaca tatccagact atttcctgcc cttggaatct gaccttcaga     7620

aggattaatg ccaaactaaa ctgacctgaa acagttttgt tactattggc attccttgac     7680

taaaaaggac cacctgatgc tcagtcccga gagtaggaat cgtggtttat tatttttcat     7740

atccatacca cctagttcag tacctgttat agagtgttta attgctgata ctaggaatta     7800

agggattttt taaaagtagc aaatagttta aggaacaatc aaaaaatgaa ttttctaatt     7860

cagttttttc aatgaagtcc catcactgaa ctttataatg taatgtttat taagcagaca     7920

tccccttaaa tactcagttt ctttggagag agcaaagcat atctctctgt ggaaattata     7980

tataatgcct ggtattttac actcaaagca aggtgttggc caggaaggta aagaaatggt     8040

gtctatgtag acttaatatc actagtctaa gtgtcatttt gagcctagta gcactacctt     8100

ccaagtgagt cacaacaaat ttgatcctat ttggtatgtt tttgtccact gttatgattc     8160

atcatgtatc ttacaagagc cactcaagca agactctgct tctatgtatg gtgaggcctt     8220

gttgttctag gctagaataa actctttgta tgcctcattg aatatgccag gtaaaattta     8280

tgcagtcaag aatgaattat ttttctgact aaagtgtgta gcagtagttc aaaattgtgc     8340

ccttgtttta acagtttctg tcaacatctt ctcatttttc cctacaaaaa caccagggtg     8400

tattataagt actgcctgtg agaatttgca ctttatgtat ttgtgtgtgg atttcttgtg     8460

gttttagcca aatgaagtgt tatcagtaat aaacaggtct cttcataggc atg            8513


<210>  1155
<211>  3320
<212>  DNA
<213>  homo sapiens

<400>  1155
gcacgtccaa accccggggt cctcggccag gccagggggg cgggcgtgcg gcggggccgg       60

gccgggccgg gcgcgcccag cgggctccgg gcacacgccc ctcacctggg cgaggcccgg      120

tgcgcaggcg ctcagcgcgg gggcagcggc cgggcgctta agcccggcgc gggcaagagt      180

tggacagttc aggggccgcg ccgggccgag ctgtcgcccg cgccacctcc accgccgccg      240

ctgctaccgc caccgccacc gcctgggctg cagcagatcg cgggagaacg tctgcgcgaa      300

gccccggtgc agccctggcg ggaccgcagc aaccaccgga gcgtgagcaa cagcttcccg      360

gctggaggag ccactgcccc acgcgcccgc ggcccgcgcg ccgagatgtt ctacatttca      420

actccatcaa atattaaatt gatgtttatg ggctaacctg gaaaccgaaa aacagtttgt      480

ttcactacaa gaataagaaa atatgtccaa attcctgtca gctgacttat aaagggactt      540

ttagaacaca acccaatgca tgaggtactc cttaagccct gacaaccatc ttgaagatgg      600

aatcatgaat atggcaaatt ttctacgggg ctttgaagaa aaggggataa agaacgacag      660

gcctgaggac cagttgagca aagagaaaaa gaaaattctt ttctccttct gtgaggtgtg      720

caacatccag ctgaactctg cagcccaggc tcaggtgcat tccaacggca aatcccaccg      780

caaacgagtg aagcagctga gtgatgggca gcccccacca cccgcccagg ccagccccag      840

cagcaacagc agcacaggca gtacatgcca cactactacc cttcctgctc ttgtgcgcac      900

acctaccctg atgatgcagc cttcactgga tatcaaacca tttatgtctt ttccagtgga      960

cagtagttct gctgttgggc tctttccaaa ttttaacaca atggatcctg tgcaaaaagc     1020

ggttattaac catacatttg gagtatccat tcccccaaag aagaaacaag ttatttcttg     1080

taatgtctgt cagcttcgct ttaactcaga tagccaggcc gaggcccact acaaaggaag     1140

taaacatgcc aagaaggtca aagcactaga cgcaacgaaa aataaaccca aaatggttcc     1200

ttccaaggac agcgcaaagg ctaatcccag ctgctccatc actccaatca caggcaacaa     1260

ctctgacaaa tcagaagata aagggaagtt aaaagccagc agttccagtc agccatcaag     1320

ctctgaaagt ggctcatttc tcctcaaatc tggcacaaca cccctgccac ctggagcagc     1380

cacttctccc tccaagagca caaatggagc tcccggtact gttgttgaat cagaagaaga     1440

aaaagccaaa aaattacttt attgttcact atgcaaagtg gctgtgaact ccctgtcaca     1500

gctagaggca cacaacacag gatctaaaca caagaccatg gttgaagctc gtaatggggc     1560

tggtccaatt aaatcctatc ctagacctgg atcaagatta aagatgcaga atggcagtaa     1620

ggggtcagga ctacagaaca agacatttca ttgtgaaatc tgtgatgttc atgttaattc     1680

agaaattcaa ctcaaacagc acatttctag ccgaaggcat aaagatcgag ttgcagggaa     1740

accactgaag ccaaaataca gcccttacaa caaactccag cggagcccga gtattctagc     1800

agcaaaactt gcattccaga aagatatgat gaagcctttg gccccagcct tcctgtcctc     1860

acctctcgca gcggcggcag ccgtgtcctc agcgctgtca ctcccacccc ggccctctgc     1920

ctcgctcttc caggctccag ccattcctcc agctcttctg aggcctgggc atgggcccat     1980

ccgcgccact cctgcctcca tcctctttgc tccgtactaa cgtctgcaaa ccccaagacg     2040

tttgaggcca gtaggaagtt gagaaagaaa gccacaagga ttcagcaatt taagcagttt     2100

gtgttgcagt accccccatt cacccacaaa atgcagccca ccacccagtc ccccaattcc     2160

agagagaaac acatcactag attgacgagg gcttttagag actgctccta taattgagga     2220

atcagcagca taggctttat ctccctactt cctcccccac cctaccgcgt tcaatttgtg     2280

tatctcagat atttgatttc ttgagcatgt attggtcaga aagaaaaaga aagaaaacca     2340

ttctctattt ttccatgggt atgatctggc ttaaaacaat atggaatatt ttcctgacag     2400

acttgaaaac taggatcttc ctcagatgtc tgtaaataac tctggtatcc aactgggtgt     2460

attctagtgt ggaacaaaaa acagtgaaca caagtgctta cttgtggata ctatcttacc     2520

aacggatcac aaagttctct ttttggtgta ctgttgttga cagggattgt gtactgtttc     2580

gacccaagta ctgctgtatc ctgtgtagta ctagatctgt atctcttgtc tgaattaaac     2640

atttttagtt gctgtgtaaa tgttaggaag caaagtagct ttgaattttc tctgtaagag     2700

aataaaagat aaaataatgt attttcttta tttcacattt tatttggaga tatttaaatg     2760

aaatagaaag ccatataaca tagctataat tactacctgt ttgctatttt tgtttaactt     2820

attttgtagc ttcctcactg gtttgtgttg ctaagcaaac gtatacaaac agaaaaagag     2880

cttcctaaat tgcacatttt tgcacctctt gtgcattctg caagaagaca atgaatccat     2940

gtatttctat ataagtatct tcttcatttt taacctgttt tcatttgtaa tgatgctaca     3000

taattttgtg gctccctaat gcaataatgt acagaagata aaaaaattta taattgaaca     3060

atttgtcttt ctgttcgctg aatatattgc aggtcatgct cccatgcccc cctttctaag     3120

ccgatatcaa caagactgga atgtttgtga tatcaggggc aagagttatc atagaacaac     3180

aaaatagagt ggactctttt agagcatcta tatctgcaac ctgtaaatgg taaaatgtct     3240

gtgtattttt ttaaatgtac cttttcaata aaagtacaaa aaataaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa                                                 3320


<210>  1156
<211>  2785
<212>  DNA
<213>  homo sapiens

<400>  1156
actcaggccc ctcccccggc gcccgcgcgc caggactggg cggcgccgac gcgcttggcg       60

ggagatagaa aagtgcttca acccgcgccg gcggcgactg cagttcctgc gagcgaggag      120

cgcgggacct gctgacacgc tgacgccttc gagcgcggcc cggggcccgg agcggccgga      180

gcagcccggg tcctgacccc ggcccggctc ccgctccggg ctctgccggc gggcgggcga      240

gcgcggcgcg gtccgggccg gggggatgtc tcggcggacg cgctgcgagg atctggatga      300

gctgcactac caggacacag attcagatgt gccggagcag agggatagca agtgcaaggt      360

caaatggacc catgaggagg acgagcagct gagggccctg gtgaggcagt ttggacagca      420

ggactggaag ttcctggcca gccacttccc taaccgcact gaccagcaat gccagtacag      480

gtggctgaga gttttgaatc cagaccttgt caaggggcca tggaccaaag aggaagacca      540

aaaagtcatc gagctggtta agaagtatgg cacaaagcag tggacactga ttgccaagca      600

cctgaagggc cggctgggga agcagtgccg tgaacgctgg cacaaccacc tcaaccctga      660

ggtgaagaag tcttgctgga ccgaggagga ggaccgcatc atctgcgagg cccacaaggt      720

gctgggcaac cgctgggccg agatcgccaa gatgttgcca gggaggacag acaatgctgt      780

gaagaatcac tggaactcta ccatcaaaag gaaggtggac acaggaggct tcttgagcga      840

gtccaaagac tgcaagcccc cagtgtactt gctgctggag ctcgaggaca aggacggcct      900

ccagagtgcc cagcccacgg aaggccaggg aagtcttctg accaactggc cctccgtccc      960

tcctaccata aaggaggagg aaaacagtga ggaggaactt gcagcagcca ccacatcgaa     1020

ggaacaggag cccatcggta cagatctgga cgcagtgcga acaccagagc ccttggagga     1080

attcccgaag cgtgaggacc aggaaggctc cccaccagaa acgagcctgc cttacaagtg     1140

ggtggtggag gcagctaacc tcctcatccc tgctgtgggt tctagcctct ctgaagccct     1200

ggacttgatc gagtcggacc ctgatgcttg gtgtgacctg agtaaatttg acctccctga     1260

ggaaccatct gcagaggaca gtatcaacaa cagcctagtg cagctgcaag cgtcacatca     1320

gcagcaagtc ctgccacccc gccagccttc cgccctggtg cccagtgtga ccgagtaccg     1380

cctggatggc cacaccatct cagacctgag ccggagcagc cggggcgagc tgatccccat     1440

ctcccccagc actgaagtcg ggggctctgg cattggcaca ccgccctctg tgctcaagcg     1500

gcagaggaag aggcgtgtgg ctctgtcccc tgtcactgag aatagcacca gtctgtcctt     1560

cctggattcc tgtaacagcc tcacgcccaa gagcacacct gttaagaccc tgcccttctc     1620

gccctcccag tttctgaact tctggaacaa acaggacaca ttggagctgg agagcccctc     1680

gctgacatcc accccagtgt gcagccagaa ggtggtggtc accacaccac tgcaccggga     1740

caagacaccc ctgcaccaga aacatgctgc gtttgtaacc ccagatcaga agtactccat     1800

ggacaacact ccccacacgc caaccccgtt caagaacgcc ctggagaagt acggacccct     1860

gaagcccctg ccacagaccc cgcacctgga ggaggacttg aaggaggtgc tgcgttctga     1920

ggctggcatc gaactcatca tcgaggacga catcaggccc gagaagcaga agaggaagcc     1980

tgggctgcgg cggagcccca tcaagaaagt ccggaagtct ctggctcttg acattgtgga     2040

tgaggatgtg aagctgatga tgtccacact gcccaagtct ctatccttgc cgacaactgc     2100

cccttcaaac tcttccagcc tcaccctgtc aggtatcaaa gaagacaaca gcttgctcaa     2160

ccagggcttc ttgcaggcca agcccgagaa ggcagcagtg gcccagaagc cccgaagcca     2220

cttcacgaca cctgccccta tgtccagtgc ctggaagacg gtggcctgcg gggggaccag     2280

ggaccagctt ttcatgcagg agaaagcccg gcagctcctg ggccgcctga agcccagcca     2340

cacatctcgg accctcatct tgtcctgagg tgttgagggt gtcacgagcc cattctcatg     2400

tttacagggg ttgtgggggc agagggggtc tgtgaatctg agagtcattc aggtgacctc     2460

ctgcagggag ccttctgcca ccagcccctc cccagactct caggtggagg caacagggcc     2520

atgtgctgcc ctgttgccga gcccagctgt gggcggctcc tggtgctaac aacaaagttc     2580

cacttccagg tctgcctggt tccctcccca aggccacagg gagctccgtc agcttctccc     2640

aagcccacgt caggcctggc ctcatctcag accctgctta ggatggggga tgtggccagg     2700

ggtgctcctg tgctcaccct ctcttggtgc atttttttgg aagaataaaa ttgcctctct     2760

ctttgtgctg gtctggaaaa aaaaa                                           2785


<210>  1157
<211>  1124
<212>  DNA
<213>  homo sapiens

<400>  1157
gccccgtcgg gggcccggag ggggactcgg agcgggccaa ggggcggctc cggcgggcgg       60

actcggagcg ggcggcggag tgacccggac agctgtcctc tctgacacca ccccggcctg      120

cctctttgtt gccatgagag ctgcctacct cttcctgcta ttcctgcctg caggcttgct      180

ggctcagggc cagtatgacc tggacccgct gccgccgttc cctgaccacg tccagtacac      240

ccactatagc gaccagatcg acaacccaga ctactatgat tatcaagagg tgactcctcg      300

gccctccgag gaacagttcc agttccagtc ccagcagcaa gtccaacagg aagtcatccc      360

agccccaacc ccagaaccag gaaatgcaga gctggagccc acagagcctg ggcctcttga      420

ctgccgtgag gaacagtacc cgtgcacccg cctctactcc atacacaggc cttgcaaaca      480

gtgtctcaac gaggtctgct tctacagcct ccgccgtgtg tacgtcatta acaaggagat      540

ctgtgttcgt acagtgtgtg cccatgagga gctcctccga gctgacctct gtcgggacaa      600

gttctccaaa tgtggcgtga tggccagcag cggcctgtgc caatccgtgg cggcctcctg      660

tgccaggagc tgtgggagct gctagggtgg tgctggcatc ctgagtcctg gccctcctgg      720

gatctggggc cctcgggccc tgcctgacct ggtgcttttt tccccatccc catgttcctt      780

ttattctgta aaaagttagt ggactgcagc cctgggggtt gcaggctgcg gtgcctcagg      840

cccctccttc agcctgtggc cacctctggg gcacaatggg ggctccccac tgcccagtct      900

gcccctcggg ttgggggagt atcccaggcc tctctgtggg acctgggccc ctgacgggcc      960

ttctcagccc gttttgagga cagacagtcc cccgaggtag gctacatccc cccaccccag     1020

ctggtctgct tggatttcct acagcccccg tgggcatgga ccacctttat tttatacaaa     1080

attaaaaaca agtttttaca aaaaaaaaaa aaaaaaaaaa aaaa                      1124


<210>  1158
<211>  2591
<212>  DNA
<213>  homo sapiens

<400>  1158
gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt       60

ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt      120

gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca      180

gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc      240

tctgagtcag gaaacatttt cagacctatg gaaactactt cctgaaaaca acgttctgtc      300

ccccttgccg tcccaagcaa tggatgattt gatgctgtcc ccggacgata ttgaacaatg      360

gttcactgaa gacccaggtc cagatgaagc tcccagaatg ccagaggctg ctccccccgt      420

ggcccctgca ccagcagctc ctacaccggc ggcccctgca ccagccccct cctggcccct      480

gtcatcttct gtcccttccc agaaaaccta ccagggcagc tacggtttcc gtctgggctt      540

cttgcattct gggacagcca agtctgtgac ttgcacgtac tcccctgccc tcaacaagat      600

gttttgccaa ctggccaaga cctgccctgt gcagctgtgg gttgattcca cacccccgcc      660

cggcacccgc gtccgcgcca tggccatcta caagcagtca cagcacatga cggaggttgt      720

gaggcgctgc ccccaccatg agcgctgctc agatagcgat ggtctggccc ctcctcagca      780

tcttatccga gtggaaggaa atttgcgtgt ggagtatttg gatgacagaa acacttttcg      840

acatagtgtg gtggtgccct atgagccgcc tgaggttggc tctgactgta ccaccatcca      900

ctacaactac atgtgtaaca gttcctgcat gggcggcatg aaccggaggc ccatcctcac      960

catcatcaca ctggaagact ccagtggtaa tctactggga cggaacagct ttgaggtgcg     1020

tgtttgtgcc tgtcctggga gagaccggcg cacagaggaa gagaatctcc gcaagaaagg     1080

ggagcctcac cacgagctgc ccccagggag cactaagcga gcactgccca acaacaccag     1140

ctcctctccc cagccaaaga agaaaccact ggatggagaa tatttcaccc ttcagatccg     1200

tgggcgtgag cgcttcgaga tgttccgaga gctgaatgag gccttggaac tcaaggatgc     1260

ccaggctggg aaggagccag gggggagcag ggctcactcc agccacctga agtccaaaaa     1320

gggtcagtct acctcccgcc ataaaaaact catgttcaag acagaagggc ctgactcaga     1380

ctgacattct ccacttcttg ttccccactg acagcctccc acccccatct ctccctcccc     1440

tgccattttg ggttttgggt ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac     1500

ccaggacttc catttgcttt gtcccggggc tccactgaac aagttggcct gcactggtgt     1560

tttgttgtgg ggaggaggat ggggagtagg acataccagc ttagatttta aggtttttac     1620

tgtgagggat gtttgggaga tgtaagaaat gttcttgcag ttaagggtta gtttacaatc     1680

agccacattc taggtagggg cccacttcac cgtactaacc agggaagctg tccctcactg     1740

ttgaattttc tctaacttca aggcccatat ctgtgaaatg ctggcatttg cacctacctc     1800

acagagtgca ttgtgagggt taatgaaata atgtacatct ggccttgaaa ccacctttta     1860

ttacatgggg tctagaactt gacccccttg agggtgcttg ttccctctcc ctgttggtcg     1920

gtgggttggt agtttctaca gttgggcagc tggttaggta gagggagttg tcaagtctct     1980

gctggcccag ccaaaccctg tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa     2040

tctcacccca tcccacaccc tggaggattt catctcttgt atatgatgat ctggatccac     2100

caagacttgt tttatgctca gggtcaattt cttttttctt tttttttttt ttttttcttt     2160

ttctttgaga ctgggtctcg ctttgttgcc caggctggag tggagtggcg tgatcttggc     2220

ttactgcagc ctttgcctcc ccggctcgag cagtcctgcc tcagcctccg gagtagctgg     2280

gaccacaggt tcatgccacc atggccagcc aacttttgca tgttttgtag agatggggtc     2340

tcacagtgtt gcccaggctg gtctcaaact cctgggctca ggcgatccac ctgtctcagc     2400

ctcccagagt gctgggatta caattgtgag ccaccacgtc cagctggaag ggtcaacatc     2460

ttttacattc tgcaagcaca tctgcatttt caccccaccc ttcccctcct tctccctttt     2520

tatatcccat ttttatatcg atctcttatt ttacaataaa actttgctgc cacctgtgtg     2580

tctgaggggt g                                                          2591


<210>  1159
<211>  2162
<212>  DNA
<213>  homo sapiens

<400>  1159
agatctcatt ccgcctccct ctgtcgtcgc cccttcccaa ttctcgcgag acctcaagga       60

gcacagcttc tgcgcaccgc acgatactgg gagtccaggc gccaagggag ggggaaggga      120

aaaggggaaa cggtgcaaac ggcgtggccg ccatcttgct tgtgcccccg cttcgcgcgc      180

gctccgttct ccgtgacgca cacttccccc tcccctccgc cgcgcctggg cctctgcatt      240

gcccgactcc gtaggagcgc gggggcggct cctgctcttc ctggactcct gagcagagtt      300

gtcgagatgt ccacagaagg aggatttggt ggtactagca gcagtgatgc ccagcaaagc      360

ctacagtcgt tctggcctcg ggtcatggaa gaaatccgga atttaacagt gaaagacttc      420

cgagtgcagg aactcccact ggctcgtatt aagaagatta tgaaactgga tgaagatgtg      480

aagatgatca gtgcagaagc gcctgtactc tttgccaagg cagcccagat ttttatcaca      540

gagttgactc ttcgagcctg gattcacaca gaagataaca agcgccggac tctacagaga      600

aatgatatcg ccatggcaat tacaaaattt gatcagtttg attttctcat cgatattgtt      660

ccaagagatg aactgaaacc tccaaagcgt caggaggagg tgcgccagtc tgtaactcct      720

gccgagccag tccagtacta tttcacgctg gctcagcaac ccaccgctgt ccaagtccag      780

ggccagcagc aaggccagca gaccaccagc tccacgacca ccatccagcc tgggcagatc      840

atcatcgcac agcctcagca gggccagacc acacctgtga caatgcaggt tggagaaggt      900

cagcaggtgc agattgtcca ggctcagcca cagggtcaag cccaacaggc ccagagtggc      960

actggacaga ccatgcaggt gatgcagcag atcatcacta acacaggaga gatccagcag     1020

atcccggtgc agctgaatgc cggccagctg cagtatatcc gcttagccca gcctgtatca     1080

ggcactcaag ttgtgcaggg acagatccag acacttgcca ccaatgctca acaggggcaa     1140

agaaatgcaa gtcaggggaa gcctcgaagg tgcctgaaag aaaccttaca gattacacag     1200

acagaggtcc agcaaggaca gcagcagttc agccagttca cagatggaca gcagctctac     1260

cagatccagc aagtcaccat gcctgcgggc caggacctcg cccagcccat gttcatccag     1320

tcagccaacc agccctccga cgggcaggcc ccccaggtga ccggcgactg agggcctgag     1380

ctggcaaggc caaggacacc caacacaatt tttgccatac agccccaggc aatgggcaca     1440

gccttcctcc ccagaggacc cggccgacct cagcgcctcc tgcaggctag gacactggtg     1500

cactacaccc catgcctggg ggccgagatt ctccagcaga aagatgcaat attttttgtt     1560

tccttttttt ccattttttt ctctaaggaa tcaatatttc aatatgttga gtgtgtgtcc     1620

aatgctatga aattaaaata ttaaataaca tatttatggc attttcttga agagtgtggt     1680

tgaagaaata tttctccttt tgtttttctt ttttttttgt ttgttactgc cacttctttt     1740

taggagcaaa tctccccagg ggtgtacggt atttcttgac tctgggaaca gctgctaccc     1800

ccaagacttg ccacgttgtt ctgccctcag atggaattag gtgaatgtgt gtagctgctt     1860

tttcactcgt ggtcctctcc ccatcccttg ctctgacccc agagctctgt gtatttgcat     1920

ccagaggcca tggaaacatt ctttgcattt aagagacaga tttattccct gtggagagtg     1980

ggtggattca ttgccacact cttttctccc agggacccag gaaactagga ctttgtgtgt     2040

ttgctgccca cctccctttt attttttaaa tgcattaaaa actgtgctag tctcctttgc     2100

atggacttca agctgcatga aatgcaataa atctcatttt agataaaaaa aaaaaaaaaa     2160

aa                                                                    2162


<210>  1160
<211>  1991
<212>  DNA
<213>  homo sapiens

<400>  1160
agatctcatt ccgcctccct ctgtcgtcgc cccttcccaa ttctcgcgag acctcaagga       60

gcacagcttc tgcgcaccgc acgatactgg gagtccaggc gccaagggag ggggaaggga      120

aaaggggaaa cggtgcaaac ggcgtggccg ccatcttgct tgtgcccccg cttcgcgcgc      180

gctccgttct ccgtgacgca cacttccccc tcccctccgc cgcgcctggg cctctgcatt      240

gcccgactcc gtaggagcgc gggggcggct cctgctcttc ctggactcct gagcagagtt      300

gtcgagatgt ccacagaagg aggatttggt ggtactagca gcagtgatgc ccagcaaagc      360

ctacagtcgt tctggcctcg ggtcatggaa gaaatccgga atttaacagt gaaagacttc      420

cgagtgcagg aactcccact ggctcgtatt aagaagatta tgaaactgga tgaagatgtg      480

aagagaaatg atatcgccat ggcaattaca aaatttgatc agtttgattt tctcatcgat      540

attgttccaa gagatgaact gaaacctcca aagcgtcagg aggaggtgcg ccagtctgta      600

actcctgccg agccagtcca gtactatttc acgctggctc agcaacccac cgctgtccaa      660

gtccagggcc agcagcaagg ccagcagacc accagctcca cgaccaccat ccagcctggg      720

cagatcatca tcgcacagcc tcagcagggc cagaccacac ctgtgacaat gcaggttgga      780

gaaggtcagc aggtgcagat tgtccaggct cagccacagg gtcaagccca acaggcccag      840

agtggcactg gacagaccat gcaggtgatg cagcagatca tcactaacac aggagagatc      900

cagcagatcc cggtgcagct gaatgccggc cagctgcagt atatccgctt agcccagcct      960

gtatcaggca ctcaagttgt gcagggacag atccagacac ttgccaccaa tgctcaacag     1020

attacacaga cagaggtcca gcaaggacag cagcagttca gccagttcac agatggacag     1080

cagctctacc agatccagca agtcaccatg cctgcgggcc aggacctcgc ccagcccatg     1140

ttcatccagt cagccaacca gccctccgac gggcaggccc cccaggtgac cggcgactga     1200

gggcctgagc tggcaaggcc aaggacaccc aacacaattt ttgccataca gccccaggca     1260

atgggcacag ccttcctccc cagaggaccc ggccgacctc agcgcctcct gcaggctagg     1320

acactggtgc actacacccc atgcctgggg gccgagattc tccagcagaa agatgcaata     1380

ttttttgttt cctttttttc catttttttc tctaaggaat caatatttca atatgttgag     1440

tgtgtgtcca atgctatgaa attaaaatat taaataacat atttatggca ttttcttgaa     1500

gagtgtggtt gaagaaatat ttctcctttt gtttttcttt tttttttgtt tgttactgcc     1560

acttcttttt aggagcaaat ctccccaggg gtgtacggta tttcttgact ctgggaacag     1620

ctgctacccc caagacttgc cacgttgttc tgccctcaga tggaattagg tgaatgtgtg     1680

tagctgcttt ttcactcgtg gtcctctccc catcccttgc tctgacccca gagctctgtg     1740

tatttgcatc cagaggccat ggaaacattc tttgcattta agagacagat ttattccctg     1800

tggagagtgg gtggattcat tgccacactc ttttctccca gggacccagg aaactaggac     1860

tttgtgtgtt tgctgcccac ctccctttta ttttttaaat gcattaaaaa ctgtgctagt     1920

ctcctttgca tggacttcaa gctgcatgaa atgcaataaa tctcatttta gataaaaaaa     1980

aaaaaaaaaa a                                                          1991


<210>  1161
<211>  3115
<212>  DNA
<213>  homo sapiens

<400>  1161
aaagcagtgg tgttttacca ctctgcagag aaagctaagg ttgctaacca aacaaaataa       60

ctttacactg acaatgccaa tttttacatt tctttcagaa caagggacac tcaaactacc      120

agagaaacgg accaatggac tgcgaagaac tcctaaacag gtggatccag gtttaccaaa      180

gatgcaggtc attaggaact attctggaac accaccccca gctctgcatg aaggaccccc      240

tttacagctc caggccgggg ataccgttga acttctgaaa ggagatgcac acagtctgtt      300

ttggcagggc agaaatttag catctggaga ggttggattt tttccaagtg atgcagtcaa      360

gccttgccca tgtgtgccca aaccagtaga ttattcttgc caaccctggt atgctggagc      420

aatggaaaga ttgcaagcag agaccgaact tattaatagg gtaaatagta cttaccttgt      480

gaggcacagg accaaagagt caggagaata tgcaattagc attaagtaca ataatgaagc      540

aaagcacatc aagattttaa caagagatgg cttttttcac attgcagaaa atagaaaatt      600

taaaagttta atggaacttg tggagtacta caagcatcat tctctcaagg aagggttcag      660

aaccttagat acaactctgc agtttccata caaggagcca gaacattcag ctggacagag      720

gggtaataga gcaggcaaca gcttgttaag tccaaaagtg ctgggcattg ccatcgctcg      780

gtatgacttc tgtgcaagag atatgagaga gttgtccttg ttgaaaggag atgtggtgaa      840

gatttacaca aagatgagtg caaatggctg gtggagagga gaagtaaatg gcagggtggg      900

ctggtttcca tccacatatg tggaagagga tgaataaatt caaatcccgt gttgcaccct      960

gcaccaaaaa tttcagagaa gggataaata gaagcctgca cagcatcgtg aattaactga     1020

agtgtttaaa aagctgcatt tctggctgtt caacatcctc cctccttagc ccctcctaag     1080

tcttaatgct gagatttcta aagatgctgg tactgacaga ttaatggctt gcctagagct     1140

gtgcaagaaa cagcctgcca gtctgtcatt gtcagggacc agggcaaaac caagagctgt     1200

tcttcccaga agagccctgc aaacacattg gttcgtgctt ccctttactt cttctggtca     1260

gataccatga atgccagtca tcagtaaatc ttaatacact tttgctttat tctcacatgc     1320

cattcaccag attatttgat ggtacaaaga agcagaagtg taattttcct tttcccagca     1380

tgacgaaaaa ttggagttct gccatttgag cagcttactg gaaagatcca gccttacttg     1440

tcttaaattg tccaacaagg tgactcattg cccggcaaac acttttaccc tcagatgtta     1500

ctcatgatat tataaaatat gaggccagtg ctcaggtttg catcataagt gagctatccc     1560

tgaagggttt taattactta tttggtgtcc tgattatatt tgcaaacttc tttataaaag     1620

gtgaaaaaag cacacaaaag agagggtgtc ttcatattaa accttcacaa ccttcatgat     1680

ttcataggat tattttggaa atatagcact tgactttatg aaaggatctg ggctaggtat     1740

attaagggta gttgccaata acctgaagaa gctggcattg tttacagaaa cagatcaagg     1800

gctataattt atgtcatttt atagcagcag tatctattaa tacatgcctt ttcctcccat     1860

ccacctcccc cgcacacaca caaagatgac ctgggacatg atttttttat tcccacattt     1920

tcttggagca caaacaactt tgttgaggat tttggaagga aagcacaact gggtccttta     1980

ttcatttctg ggacagaaag agggtcagtg gacttttgtg ggcctccagc ttctctcaga     2040

gtctccccct ctgcagccca tcctgggagt gtattaactg gagggaagat gggtcttgca     2100

gtacatttgt tttgcccagc catcactctt ttttgtgagg agcctaaata cattcttcct     2160

ggggtccaga gtccccattc aaggcagtca agttaagaca ctaacttggc cctttcctga     2220

tggaaatatt tcctccatag cagaagttgt gttctgacaa gactgagaga gttacatgtt     2280

gggaaaaaaa agaagcatta acttagtaga actgaaccag gagcattaag ttctgaaatt     2340

ttgaatcatc tctgaaatga agcaggtgta gcctgccctc tcatcaatcc gtctgggtgc     2400

cagaactcaa ggttcagtgg acacatcccc ctgttagaga ccctcatggg ctaggacttt     2460

tcatctagga tagattcaag acctttacct cagaattatg taaactgtga ttgtgtttta     2520

gaaaaattat tatttgctaa aaccatttaa gtctttgtat atgtgtaaat gatcacaaaa     2580

atgtatttta taaaatgttc tgtacaataa agttacacct caaagtgtac tcttggaatg     2640

gattctttcc tgtaaagtct tatctgcgac tctgtctcgg gaatgttttg tctgttgccg     2700

tcagccgaac tttgttatgg agggagcagc ctcacacaag cagaaacact cctgtggatg     2760

gtattgtagc atgtattgtt tattttagtc aatagaccct ctccttataa atggtgttta     2820

gtcttcctgt tgcatttcat gggcctgggg gtttcctagc agaggatatt ggagcccctt     2880

tttgtgacat taccaattac atctttgtcc acgtttaata ctttgttttg gaaaatttaa     2940

atgctgcaga tttgtgtaga gttctaatac caaagacaga agtaaatgtt ttccatatac     3000

tttgtcttgc ctgtatgcag ccctcgtgta atacggtgaa ttagagtggt atttcacttt     3060

gtattatttt gtaaatatgt caatataata aatagtgact aaattgataa aaaaa          3115


<210>  1162
<211>  4776
<212>  DNA
<213>  homo sapiens

<400>  1162
cggccgcatc cttgccgccc gccccggccc agccgcgtcc cggagccgtc gggcatggag       60

ccgtggaagc agtgcgcgca gtggctcatc cattgcaagg tgctgcccac caaccaccgg      120

gtgacctggg actcggctca ggtgttcgac cttgcgcaga ccctccgcga tggagtcctg      180

ctctgccagc tgcttaacaa cctccgggcg cactccatca acctgaagga gatcaacctg      240

aggccgcaga tgtcccagtt tctctgtttg aagaacataa ggacatttct cacggcctgt      300

tgtgagacgt ttggaatgag gaaaagtgaa cttttcgagg catttgactt gtttgatgtt      360

cgtgactttg gaaaggttat agaaacatta tcacgacttt ctcgaacacc tatagcattg      420

gccacaggaa tcaggccctt cccaacagaa gaaagcatta atgatgaaga catctacaaa      480

ggccttcctg atttaataga tgaaaccctt gtggaagatg aagaagatct ctatgactgt      540

gtttatgggg aagatgaagg tggagaagtc tatgaggact taatgaaggc agaggaagca      600

catcagccca aatgtccaga aaatgatata cgaagttgtt gtctagcaga aattaagcag      660

acagaagaaa aatatacaga aactttggag tcaatagaaa agtatttcat ggcaccacta      720

aaaagatttc tgacagcagc agaatttgat tcagtattca tcaacattcc tgaacttgta      780

aaacttcatc ggaacctaat gcaagagatt catgattcca ttgtaaataa aaatgaccag      840

aacttgtacc aagtttttat taactacaag gaaagattgg ttatttacgg gcagtactgc      900

agtggagtgg agtcagccat ctctagttta gactacattt ctaagacaaa agaagatgtc      960

aaactgaaat tagaggaatg ttccaaaaga gcaaataatg ggaaatttac tcttcgagac     1020

ttgcttgtgg ttcctatgca acgtgtttta aagtaccacc ttctcctcca ggaactggtc     1080

aaacatacca ctgatccgac tgagaaggca aatctgaaac tggctcttga tgccatgaag     1140

gacttggcac aatatgtgaa tgaagtgaaa agagataatg agacccttcg tgaaattaaa     1200

cagtttcagc tatctataga gaatttgaac caaccagttt tgctttttgg acgacctcag     1260

ggagatggtg aaattcgaat aaccactcta gacaagcata ccaaacaaga aaggcatatc     1320

ttcttatttg atttggcagt gatcgtatgt aagagaaaag gtgataacta tgaaatgaag     1380

gaaataatag atcttcagca gtacaagata gccaataatc ctacaaccga taaagaaaac     1440

aaaaagtggt cttatggctt ctacctcatc catacccaag gacaaaatgg gttagaattt     1500

tattgcaaaa caaaagattt aaagaagaaa tggctagaac agtttgaaat ggctttgtct     1560

aacataagac cagactatgc agactccaat ttccacgact tcaagatgca taccttcact     1620

cgagtcacat cctgcaaagt ctgccagatg ctcctgaggg gaacatttta tcaaggctat     1680

ttatgtttta agtgtggagc gagagcacac aaagaatgtt tgggaagagt agacaattgt     1740

ggcagagtta attctggtga acaagggaca ctcaaactac cagagaaacg gaccaatgga     1800

ctgcgaagaa ctcctaaaca ggtggatcca ggtttaccaa agatgcaggt cattaggaac     1860

tattctggaa caccaccccc agctctgcat gaaggacccc ctttacagct ccaggccggg     1920

gataccgttg aacttctgaa aggagatgca cacagtctgt tttggcaggg cagaaattta     1980

gcatctggag aggttggatt ttttccaagt gatgcagtca agccttgccc atgtgtgccc     2040

aaaccagtag attattcttg ccaaccctgg tatgctggag caatggaaag attgcaagca     2100

gagaccgaac ttattaatag ggtaaatagt acttaccttg tgaggcacag gaccaaagag     2160

tcaggagaat atgcaattag cattaagtac aataatgaag caaagcacat caagatttta     2220

acaagagatg gcttttttca cattgcagaa aatagaaaat ttaaaagttt aatggaactt     2280

gtggagtact acaagcatca ttctctcaag gaagggttca gaaccttaga tacaactctg     2340

cagtttccat acaaggagcc agaacattca gctggacaga ggggtaatag agcaggcaac     2400

agcttgttaa gtccaaaagt gctgggcatt gccatcgctc ggtatgactt ctgtgcaaga     2460

gatatgagag agttgtcctt gttgaaagga gatgtggtga agatttacac aaagatgagt     2520

gcaaatggct ggtggagagg agaagtaaat ggcagggtgg gctggtttcc atccacatat     2580

gtggaagagg atgaataaat tcaaatcccg tgttgcaccc tgcaccaaaa atttcagaga     2640

agggataaat agaagcctgc acagcatcgt gaattaactg aagtgtttaa aaagctgcat     2700

ttctggctgt tcaacatcct ccctccttag cccctcctaa gtcttaatgc tgagatttct     2760

aaagatgctg gtactgacag attaatggct tgcctagagc tgtgcaagaa acagcctgcc     2820

agtctgtcat tgtcagggac cagggcaaaa ccaagagctg ttcttcccag aagagccctg     2880

caaacacatt ggttcgtgct tccctttact tcttctggtc agataccatg aatgccagtc     2940

atcagtaaat cttaatacac ttttgcttta ttctcacatg ccattcacca gattatttga     3000

tggtacaaag aagcagaagt gtaattttcc ttttcccagc atgacgaaaa attggagttc     3060

tgccatttga gcagcttact ggaaagatcc agccttactt gtcttaaatt gtccaacaag     3120

gtgactcatt gcccggcaaa cacttttacc ctcagatgtt actcatgata ttataaaata     3180

tgaggccagt gctcaggttt gcatcataag tgagctatcc ctgaagggtt ttaattactt     3240

atttggtgtc ctgattatat ttgcaaactt ctttataaaa ggtgaaaaaa gcacacaaaa     3300

gagagggtgt cttcatatta aaccttcaca accttcatga tttcatagga ttattttgga     3360

aatatagcac ttgactttat gaaaggatct gggctaggta tattaagggt agttgccaat     3420

aacctgaaga agctggcatt gtttacagaa acagatcaag ggctataatt tatgtcattt     3480

tatagcagca gtatctatta atacatgcct tttcctccca tccacctccc ccgcacacac     3540

acaaagatga cctgggacat gattttttta ttcccacatt ttcttggagc acaaacaact     3600

ttgttgagga ttttggaagg aaagcacaac tgggtccttt attcatttct gggacagaaa     3660

gagggtcagt ggacttttgt gggcctccag cttctctcag agtctccccc tctgcagccc     3720

atcctgggag tgtattaact ggagggaaga tgggtcttgc agtacatttg ttttgcccag     3780

ccatcactct tttttgtgag gagcctaaat acattcttcc tggggtccag agtccccatt     3840

caaggcagtc aagttaagac actaacttgg ccctttcctg atggaaatat ttcctccata     3900

gcagaagttg tgttctgaca agactgagag agttacatgt tgggaaaaaa aagaagcatt     3960

aacttagtag aactgaacca ggagcattaa gttctgaaat tttgaatcat ctctgaaatg     4020

aagcaggtgt agcctgccct ctcatcaatc cgtctgggtg ccagaactca aggttcagtg     4080

gacacatccc cctgttagag accctcatgg gctaggactt ttcatctagg atagattcaa     4140

gacctttacc tcagaattat gtaaactgtg attgtgtttt agaaaaatta ttatttgcta     4200

aaaccattta agtctttgta tatgtgtaaa tgatcacaaa aatgtatttt ataaaatgtt     4260

ctgtacaata aagttacacc tcaaagtgta ctcttggaat ggattctttc ctgtaaagtc     4320

ttatctgcga ctctgtctcg ggaatgtttt gtctgttgcc gtcagccgaa ctttgttatg     4380

gagggagcag cctcacacaa gcagaaacac tcctgtggat ggtattgtag catgtattgt     4440

ttattttagt caatagaccc tctccttata aatggtgttt agtcttcctg ttgcatttca     4500

tgggcctggg ggtttcctag cagaggatat tggagcccct ttttgtgaca ttaccaatta     4560

catctttgtc cacgtttaat actttgtttt ggaaaattta aatgctgcag atttgtgtag     4620

agttctaata ccaaagacag aagtaaatgt tttccatata ctttgtcttg cctgtatgca     4680

gccctcgtgt aatacggtga attagagtgg tatttcactt tgtattattt tgtaaatatg     4740

tcaatataat aaatagtgac taaattgata aaaaaa                               4776


<210>  1163
<211>  2403
<212>  DNA
<213>  homo sapiens

<400>  1163
aagctttgaa ccgagtttgg ggagctcagc agcatcatgc ttagactttt caaagagaca       60

aactccattt tcttatgaat ggaaagtgaa aacccctgtt ccgcttaaat tgggttcctt      120

cctgtcctga gaaacataga gacccccaaa agggaagcag aggagagaaa gtcccacacc      180

cagaccccgc gagaagagat gaccatgacc accatgccag aaagtctcaa cagccccgtg      240

tcgggcaagg cggtgtttat ggagtttggg ccgcccaacc agcaaatgtc tccttctccc      300

atgtcccacg ggcactactc catgcactgt ttacactcgg cgggccattc gcagcccgac      360

ggcgcctaca gctcagcctc gtccttctcc cgaccgctgg gctaccccta cgtcaactcg      420

gtcagcagcc acgcatccag cccctacatc agttcggtgc agtcctaccc gggcagcgcc      480

agcctcgccc agagccgcct ggaggaccca ggggcggact cggagaagag cacggtggtg      540

gaaggcggtg aagtgcgctt caatggcaag ggaaaaaaga tccgtaaacc caggacgatt      600

tattccagtt tgcagttgca ggctttgaac cggaggttcc agcaaactca gtacctagct      660

ctgccggaga gggcggagct cgcggcctct ttgggactca cacagactca ggtcaagatc      720

tggttccaaa acaagcgatc caagttcaag aagctgatga agcagggtgg ggcggctctg      780

gagggtagtg cgttggccaa cggtcgggcc ctgtctgctg gctccccacc cgtgccgccc      840

ggctggaacc ctaactcttc atccgggaag ggctcaggag gaaacgcggg ctcctatatc      900

cccagctaca catcgtggta cccttcagcg caccaagaag ctatgcagca accccaactt      960

atgtgaggtt gcccgcccgt ctccttcttg tctccccggc ccaggtccct cccgcctcca     1020

ggtccatcca tcccgtccgg aaaagaagga cccagaggga agaaggaaca gtggaggcgg     1080

gacgccctcc atctcctcgg agccccgcga ggtccggccc agcaacttcc cggcatccgc     1140

gctctagcct gaaccctggc ctgggccgag cagtggcagc agagagtggc ctcggaggga     1200

agccactgcc acctgagaca gcccaagcag caagataaac ccgctccacc cgacccgccg     1260

accttcagct ttgtgggact atcaggaaaa aacaaaacaa aaacaaaatg tagaaaaagc     1320

aaaagctctt ttctgtcctg tcagtctcct gtctcctttt gctctgtctg tgcgctggta     1380

aagtccaggt cctcatccgt ccgctgtcct cattctgcgg cctcagcaaa aagccacaag     1440

gtctgagcgg cccgggtcct gccgggctga ccatctccgg atcctgggac actctgcctg     1500

accatctgtg tagctggtgt gggaatctgg gggcattgga gggagggggt tttatttatt     1560

gagaaatgga cttcgcctga ggctgtttgc caattcaggg ttctgctggg cgcaaggaac     1620

gcactgttca aacgcactgt ttactttaag cgcacgggga gaaacgaata aggaggacgt     1680

ggtgattttt aatttataca gtaacttttg tacttctctg gtatggagag tttggagccg     1740

aatgatttgc attttttaca tgtccgacat tatttaataa ataattttta aaagaaaaga     1800

acgataaatg aagccaacat gattttctca tttcgggagg aactctgttg cttcgcctgg     1860

acaagaagga aaatgctgat ttcctccttg ggtagaaaga gggagcgagg gcaaatgggg     1920

agtagagaga aaacaggcga gaacaagcac tctaattcca gtgggcttta aaataagaca     1980

aaatcagctt tacaacaatc cctagaggct cgaccacaga ataatgccag tcaccaccct     2040

gaacgcacaa tctccagtgc aggatctaat gactgtacat attattgtta ttattattat     2100

tgttattatt gttgttctgt aaacatgttg cacaagctta gcctttttgc gttctgttgt     2160

gtgtggctgt aaaaccccat gctttgtgaa atgagaatct tgacattttt cttgtgaaat     2220

ttggaaaatg tgatcaattg aaatcaactg tgttttgtgt tctctatgtc aaagtttagt     2280

tttatattga gaatgttaac ttattgcttt gtatcttggg aaaaaaactt tgtaaataag     2340

ttataaagtt tctttgagac agtaaaatta tgatttcttg aaaaaaaaaa aaaaaaaaaa     2400

aaa                                                                   2403


<210>  1164
<211>  4793
<212>  DNA
<213>  homo sapiens

<400>  1164
aactcctccc ccaccgcccc ctccctcctt ctgctcccgc ggtctcctcc tccctgctct       60

ctccgagcgc cgggtcggga gctagttgga gcgcgggggt tggtgccaga gcccagctcc      120

gccgagccgg gcgggtcggc agcgcatcca gcggctgctg ggagcccgag cgcagcgggc      180

gcgggcccgg gtggggactg caccggagcg ctgagagctg gaggccgttc ctgcgcggcc      240

gccccattcc cagaccggcc gccagcccat ctggttagct cccgccgctc cgcgccgccc      300

gggagtcggg agccgcgggg aaccgggcac ctgcacccgc ctctgggagt gagtggttcc      360

agctggtgcc tggcctgtgt ctcttggatg ccctgtggct tcagtccgtc tcctgttgcc      420

caccacctcg tccctgggcc gcctgatacc ccagcccaac agctaaggtg tggatggaca      480

gtagggggct ggcttctctc actggtcagg ggtcttctcc cctgtctgcc tcccggagct      540

aggactgcag aggggcctat catggtgctt gcaggccccc tggctgtctc gctgttgctg      600

cccagcctca cactgctggt gtcccacctc tccagctccc aggatgtctc cagtgagccc      660

agcagtgagc agcagctgtg cgcccttagc aagcacccca ccgtggcctt tgaagacctg      720

cagccgtggg tctctaactt cacctaccct ggagcccggg atttctccca gctggctttg      780

gacccctccg ggaaccagct catcgtggga gccaggaact acctcttcag actcagcctt      840

gccaatgtct ctcttcttca ggccacagag tgggcctcca gtgaggacac gcgccgctcc      900

tgccaaagca aagggaagac tgaggaggag tgtcagaact acgtgcgagt cctgatcgtc      960

gccggccgga aggtgttcat gtgtggaacc aatgcctttt cccccatgtg caccagcaga     1020

caggtgggga acctcagccg gactattgag aagatcaatg gtgtggcccg ctgcccctat     1080

gacccacgcc acaactccac agctgtcatc tcctcccagg gggagctcta tgcagccacg     1140

gtcatcgact tctcaggtcg ggaccctgcc atctaccgca gcctgggcag tgggccaccg     1200

cttcgcactg cccaatataa ctccaagtgg cttaatgagc caaacttcgt ggcagcctat     1260

gatattgggc tgtttgcata cttcttcctg cgggagaacg cagtggagca cgactgtgga     1320

cgcaccgtgt actctcgcgt ggcccgcgtg tgcaagaatg acgtgggggg ccgattcctg     1380

ctggaggaca catggaccac attcatgaag gcccggctca actgctcccg cccgggcgag     1440

gtccccttct actataacga gctgcagagt gccttccact tgccggagca ggacctcatc     1500

tatggagttt tcacaaccaa cgtaaacagc atcgcggctt ctgctgtctg cgccttcaac     1560

ctcagtgcta tctcccaggc tttcaatggc ccatttcgct accaggagaa ccccagggct     1620

gcctggctcc ccatagccaa ccccatcccc aatttccagt gtggcaccct gcctgagacc     1680

ggtcccaacg agaacctgac ggagcgcagc ctgcaggacg cgcagcgcct cttcctgatg     1740

agcgaggccg tgcagccggt gacacccgag ccctgtgtca cccaggacag cgtgcgcttc     1800

tcacacctcg tggtggacct ggtgcaggct aaagacacgc tctaccatgt actctacatt     1860

ggcaccgagt cgggcaccat cctgaaggcg ctgtccacgg cgagccgcag cctccacggc     1920

tgctacctgg aggagctgca cgtgctgccc cccgggcgcc gcgagcccct gcgcagcctg     1980

cgcatcctgc acagcgcccg cgcgctcttc gtggggctga gagacggcgt cctgcgggtc     2040

ccactggaga ggtgcgccgc ctaccgcagc cagggggcat gcctgggggc ccgggacccg     2100

tactgtggct gggacgggaa gcagcaacgt tgcagcacac tcgaggacag ctccaacatg     2160

agcctctgga cccagaacat caccgcctgt cctgtgcgga atgtgacacg ggatgggggc     2220

ttcggcccat ggtcaccatg gcaaccatgt gagcacttgg atggggacaa ctcaggctct     2280

tgcctgtgtc gagctcgatc ctgtgattcc cctcgacccc gctgtggggg ccttgactgc     2340

ctggggccag ccatccacat cgccaactgc tccaggaatg gggcgtggac cccgtggtca     2400

tcgtgggcgc tgtgcagcac gtcctgtggc atcggcttcc aggtccgcca gcgaagttgc     2460

agcaaccctg ctccccgcca cgggggccgc atctgcgtgg gcaagagccg ggaggaacgg     2520

ttctgtaatg agaacacgcc ttgcccggtg cccatcttct gggcttcctg gggctcctgg     2580

agcaagtgca gcagcaactg tggagggggc atgcagtcgc ggcgtcgggc ctgcgagaac     2640

ggcaactcct gcctgggctg cggcgtggag ttcaagacgt gcaaccccga gggctgcccc     2700

gaagtgcggc gcaacacccc ctggacgccg tggctgcccg tgaacgtgac gcagggcggg     2760

gcacggcagg agcagcggtt ccgcttcacc tgccgcgcgc cccttgcaga cccgcacggc     2820

ctgcagttcg gcaggagaag gaccgagacg aggacctgtc ccgcggacgg ctccggctcc     2880

tgcgacaccg acgccctggt ggaggtcctc ctgcgcagcg ggagcacctc cccgcacacg     2940

gtgagcgggg gctgggccgc ctggggcccg tggtcgtcct gctcccggga ctgcgagctg     3000

ggcttccgcg tccgcaagag aacgtgcact aacccggagc cccgcaacgg gggcctgccc     3060

tgcgtgggcg atgctgccga gtaccaggac tgcaaccccc aggcttgccc agttcggggt     3120

gcttggtcct gctggacctc atggtctcca tgctcagctt cctgtggtgg gggtcactat     3180

caacgcaccc gttcctgcac cagccccgca ccctccccag gtgaggacat ctgtctcggg     3240

ctgcacacgg aggaggcact atgtgccaca caggcctgcc cagaaggctg gtcgccctgg     3300

tctgagtgga gtaagtgcac tgacgacgga gcccagagcc gaagccggca ctgtgaggag     3360

ctcctcccag ggtccagcgc ctgtgctgga aacagcagcc agagccgccc ctgcccctac     3420

agcgagattc ccgtcatcct gccagcctcc agcatggagg aggccaccga ctgtgcaggg     3480

ttcaatctca tccacttggt ggccacgggc atctcctgct tcttgggctc tgggctcctg     3540

accctagcag tgtacctgtc ttgccagcac tgccagcgtc agtcccagga gtccacactg     3600

gtccatcctg ccacccccaa ccatttgcac tacaagggcg gaggcacccc gaagaatgaa     3660

aagtacacac ccatggaatt caagaccctg aacaagaata acttgatccc tgatgacaga     3720

gccaacttct acccattgca gcagaccaat gtgtacacga ctacttacta cccaagcccc     3780

ctgaacaaac acagcttccg gcccgaggcc tcacctggac aacggtgctt ccccaacagc     3840

tgataccgcc gtcctgggga cttgggcttc ttgccttcat aaggcacaga gcagatggag     3900

atgggacagt ggagccagtt tggttttctc cctctgcact aggccaagaa cttgctgcct     3960

tgcctgtggg gggtcccatc cggcttcaga gagctctggc tggcattgac catgggggaa     4020

agggctggtt tcaggctgac atatggccgc aggtccagtt cagcccaggt ctctcatggt     4080

tatcttccaa cccactgtca cgctgacact atgctgccat gcctgggctg tggacctact     4140

gggcatttga ggaattggag aatggagatg gcaagagggc aggcttttaa gtttgggttg     4200

gagacaactt cctgtggccc ccacaagctg agtctggcct tctccagctg gccccaaaaa     4260

aggcctttgc tacatcctga ttatctctga aagtaatcaa tcaagtggct ccagtagctc     4320

tggattttct gccagggctg ggccattgtg gtgctgcccc agtatgacat gggaccaagg     4380

ccagcgcagg ttatccacct ctgcctggaa gtctatactc tacccagggc atccctctgg     4440

tcagaggcag tgagtactgg gaactggagg ctgacctgtg cttagaagtc ctttaatctg     4500

ggctggtaca ggcctcagcc ttgccctcaa tgcacgaaag gtggcccagg agagaggatc     4560

aatgccatag gaggcagaag tctggcctct gtgcctctat ggagactatc ttccagttgc     4620

tgctcaacag agttgttggc tgagacctgc ttgggagtct ctgctggccc ttcatctgtt     4680

caggaacaca cacacacaca cactcacaca cgcacacaca atcacaattt gctacagcaa     4740

caaaaaagac attgggctgt ggcattatta attaaagatg atatccagtc tcc            4793


<210>  1165
<211>  3359
<212>  DNA
<213>  homo sapiens

<400>  1165
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtaatg     1560

ggactcctga ccaaccacgg tggggtacct catcagcccc agactgatta cgcgctctcc     1620

cctctcaccg ggggtctgga acctaccacc acggtgtcgg ccagctgcag tcagagacta     1680

gaccatatga agagcttgga cagtctgcca acatctcagt cctactgtcc acccacctat     1740

agcaccacag gctacagtat ggaccctgtc acaggctacc aatatgggca gtatggacaa     1800

agtgcctttc attatctcaa gccagatatc gcgtaagtga actgtccact tggagctaaa     1860

actggccctg tttctggtct tcgcagccta gatatgaaga atctgctctg aaaacaaaaa     1920

aaaattaccc ttttgttggg gggggtgggg cagtggtccc aataggagac aaaggagagt     1980

gattgatttt cttcctccaa tagttggttt caaatccttt tgaacacgtt cgacaaaagc     2040

agtggagaag aggaagacct ggagcaataa aagacaaatg caacatttta aggcaatggt     2100

ttcacatggt tacatatcaa aacatcccaa ttctttagtg ctgatcatcg aggagctaga     2160

acattccatt tgcttgtgtg cgtgcgtgcg tgtgtgtgtg tgtgtgtgta ttgagattta     2220

cccagactgg tttgggcaag cagactgttc taaaatataa tagaataccc taaagtataa     2280

catgtcgatg ttcgatgctg atacttctac aactttaaaa ctgctcattt catgaagcaa     2340

gaatggagga atccttgact cttacacact ggaaattgaa ataaagataa atgcaaccat     2400

ttttaggaag ctagactagc tgtaaaggac ctcctaaata aattatttgt tactgtatcc     2460

tcatttgtaa tctagttgtc aataaatggc ccggacatgt cttgctaaca ggatatgggc     2520

taccaggaag aaggacttgt ttccctttcc tgtgtgggga gaggtgtgtg acgtttttcc     2580

agttcacatt tatttggtag cccacctggg ttggaggaag ggcacggtgg agagaaagtg     2640

acatgcattc acatatctgc ttatcagtgt gcaatactgt gtacctcatg gatgctttgg     2700

caatgcccaa ggcgatataa gcaaaatcag aagtatattt ttgcaggtgc ttttattttc     2760

acagcccata attcatagtg atagagtgca gtgatgtttg ccatttgctg gacaaccaac     2820

acccgggttg ctcctttgat tagagaccag atcagataat tatgctttta aactgattac     2880

gtttacattc ttctcttttc tatgaaaggc agggcaagaa cagaagtgtt cacatggctc     2940

tcatgtactt ttaaattata caatgatatc caatattaaa agattatagg aactgaggtt     3000

tacatacgtt tgtgtggtga cattttagaa tgtcaataaa tttgcttttt gagatgttga     3060

gaggaacaag aaggtggaag gcagtgttat ttatttcttt ctattcttgg aaccacgaat     3120

gaggtaggca caaatacatt ccttttagag ttaagaacta tgacgtagcg agttagtgag     3180

actagacata gtaccgaatt tagttcatgc attggtctta gagggtgatg gaacaagaga     3240

agtactatct ttgtgttgca gcctcaacca acaacaatgt gttgtaaaaa tgtctttcat     3300

gtaaaaagtg cagtaaatat ttactattta taatgaataa acagttatga aaacttgaa      3359


<210>  1166
<211>  9243
<212>  DNA
<213>  homo sapiens

<400>  1166
atttcatttc ttccactaaa gcgtttgcgg agacttcaag gtataatcta tcccagatcc       60

tttcccagag agaaacttgg cgatcacgtt ttcacatgat gctcacgctc agggcgcttc      120

aattatccct ccccacaaag ataggtggcg cgtgtttcag ggtctctcgt ctctctccta      180

cagaaaagaa aaagaaaaaa atgtcattag aagaggcgta acacgtcagt ccgtccccag      240

gtttgtgttt cctggagtgg ccgaaagaga tcagttctaa cctgctctgc aggaataacg      300

gtcctgcctc ccgacactct tggcgaggtt tttgtacagt ttgctccggg agctgtttct      360

tcgcttccac ctttttctcc cccacacttc gcggcttctt catgcttttt cttctcacca      420

tttctggcca aaactacaaa caagacttcg cagatcgagc ctgcgtgctg ccgaagcagg      480

gcgccgagtc catgcgaact gccatctgat ccgctcttat caatgaagca gccgatcatg      540

gcggatggcc cccggtgcaa gaggcgcaaa caagccaatc ccaggaggaa aaacgtggtg      600

aactatgaca atgtagtgga cacaggttct gaaacagatg aggaagacaa gcttcatatt      660

gctgaggatg acggtattgc caaccctctg gaccaggaga cgagtccagc tagtgtgccc      720

aaccatgagt cctccccaca cgtgagccaa gctctgttgc caagagagga agaggaagat      780

gaaataaggg agggtggagt ggaacacccc tggcacaaca acgagattct acaagcctct      840

gtagatggtc cagaagaaat gaaggaagac tatgacacta tggggccaga agccacgatc      900

cagaccgcaa ttaacaatgg tacagtgaag aatgcaaatt gcacatcaga ttttgaggaa      960

tactttgcca aaagaaaact ggaggaacgc gatggtcatg cagtcagcat cgaggagtac     1020

cttcagcgca gtgacacagc cattatttac ccagaagccc ctgaggagct gtctcgcctt     1080

ggcacgccag aggccaatgg gcaagaagaa aatgacctgc cacctggaac tccagatgct     1140

tttgcccaac tgctgacctg cccctactgc gaccggggct acaagcgctt gacatcactg     1200

aaggagcaca tcaagtaccg ccacgagaag aatgaagaga acttttcctg ccctctctgt     1260

agctacacgt ttgcctaccg cacccagctc gagcggcata tggtgacaca caagccaggg     1320

acagatcagc accaaatgct aacccaagga gcaggtaatc gcaagttcaa atgcacagag     1380

tgtggcaagg ccttcaaata taaacaccat ctgaaagaac acctgcgaat tcacagtggt     1440

gaaaaacctt acgagtgccc aaactgcaag aaacgtttct cccattctgg ttcctacagt     1500

tcgcacatca gcagcaagaa atgtattggt ttaatctctg taaatggccg aatgagaaac     1560

aatatcaaga cgggttcttc ccctaattct gtttcttctt ctcctactaa ttcagccatt     1620

acccagttaa gaaacaagtt ggagaatgga aaaccactta gtatgtctga acagacaggc     1680

ttacttaaaa ttaaaacaga accactagac ttcaatgact ataaagttct tatggctaca     1740

cacgggttta gtggcactag tccctttatg aatggtgggc ttggagccac cagcccttta     1800

ggagttcatc catctgctca gagtccaatg cagcacttag gtgtagggat ggaagcccct     1860

ttacttgggt ttcccaccat gaatagtaat ttaagtgagg tacaaaaggt tctacagatt     1920

gtggacaata ctgtttccag gcaaaaaatg gactgcaagg ctgaagaaat ttcaaagttg     1980

aaaggttatc acatgaagga tccatgctct caacctgagg aacaaggagt tacttctcct     2040

aatattccgc ctgtcggtct tccggtagtg agtcataatg gtgccactaa aagtattatt     2100

gactatacgt tggaaaaagt caatgaagcc aaagcttgcc tccagagctt gactactgac     2160

tcaaggagac agatcagtaa tataaagaaa gagaagctac gtactttaat agatttggtc     2220

actgatgaca aaatgattga gaaccacaac atatccactc cattttcatg ccagttctgt     2280

aaagaaagtt ttcctggccc catccctttg catcagcatg aacgttacct ttgtaagatg     2340

aatgaagaga tcaaggcggt cctgcagcct catgaaaaca tagtccccaa caaagccgga     2400

gtttttgttg ataataaagc cctcctcttg tcatctgtac tttctgagaa aggaatgaca     2460

agccccatca acccatacaa ggaccacatg tctgtactca aagcatacta tgctatgaac     2520

atggagccca actccgatga actgctgaaa atttccattg ctgtgggcct tcctcaggaa     2580

tttgtgaagg aatggtttga acaacgaaaa gtctaccagt actcaaattc caggtcccca     2640

tccctggaaa gaagctccaa gccgttagct cccaacagta accctcccac aaaagactct     2700

ttattaccca ggtctcctgt aaaacctatg gactccataa catcaccatc tatagcagaa     2760

ctccacaaca gtgttacgaa ttgtgatcct cctctcaggc taacaaaacc ttcccatttt     2820

accaatatta aaccagttga aaaattggac cactccagga gtaatactcc ttctccctta     2880

aatctttcct ccacatcttc taaaaactcc cacagtagtt catacactcc aaacagcttc     2940

tcttctgagg agctccaggc tgagccttta gacttgtcat taccaaaaca aatgaaagaa     3000

cccaaaagta ttatagccac aaagaacaaa acaaaagcta gtagcatcag tttagatcat     3060

aacagtgttt cttcctcatc tgaaaactca gatgagcctc tgaacttgac ttttatcaag     3120

aaggaatttt caaattcaaa taatctggac aacaaaagca ctaacccagt gttcagcatg     3180

aacccattta gtgccaaacc tttatacaca gctcttccac ctcaaagcgc atttccccct     3240

gctactttca tgccaccagt ccagaccagt attcctgggc tacgaccata cccaggactg     3300

gatcagatga gcttcctacc acatatggcc tacacctacc caactggagc agctactttt     3360

gctgatatgc agcaaaggag aaagtaccag cggaaacaag gatttcaggg agaattgctt     3420

gatggagcac aagactacat gtcaggccta gatgatatga cagactccga ctcctgtctg     3480

tctcgcaaaa agatcaagaa gacagagagt ggcatgtatg catgtgactt atgtgacaag     3540

acattccaga aaagcagttc ccttctgcga cataaatacg aacacacagg aaaaagacca     3600

catcagtgtc agatttgtaa gaaagcgttt aaacacaagc accaccttat cgagcactca     3660

aggcttcact cgggcgagaa gccctatcag tgtgataaat gtggcaagcg cttctcacac     3720

tcgggctcgt actcgcagca catgaatcac aggtattcct actgcaagcg ggaggcggag     3780

gagcgggaag cggcggagcg cgaggcgcgc gagaaagggc acttggaacc caccgagctg     3840

ctgatgaacc gggcttactt gcagagcatt acccctcagg ggtactctga ctcggaggag     3900

agggagagta tgccgaggga tggcgagagc gagaaggagc acgagaaaga aggcgaggat     3960

ggctacggga agctgggcag acaggatggc gacgaggagt tcgaggagga agaggaagaa     4020

agtgaaaata aaagtatgga tacggatccc gaaacgatac gagatgaaga agagactgga     4080

gatcactcca tggacgatag ttcggaggat gggaaaatgg aaaccaaatc agaccacgag     4140

gaagacaata tggaagatgg catgtaataa actactgcat tttaagcttc ctattttttt     4200

ttccagtagt attgttacct gcttgaaaac actgctgtgt taagctgttc atgcacgtgc     4260

ctgacgcttc caggaagctg tagagaggga cagaaggggc ggttcagcca agacagatgt     4320

agacggagtt ggagctgggt attgttaaaa actgcattat gcaaaaattt tgtacagtgt     4380

taaggcctaa aaactgtgtg gttcagagac taattcctgt gtttaatagc atttatactt     4440

taagcacaac tagaaaattg taagaattgc actctactta tgtatcacta caaactttaa     4500

aaaactatgt ctaatttata ttaatacatt ttaaaaaggt gcccgcacta ccatacatca     4560

gtatttttat tattattatt gttattcctt tttaatttaa tgtgctcgca ctacaatgca     4620

tcagtattat gattcctctg tactttcctt tcgctattca tcaatttccc attttttttt     4680

tcagcttaag taaccacaca attttaggcc tcaatttttt tttttttctg tgaaggaact     4740

tgaagtgatg catgtgtgaa tttaagatac cgaagtctta aagtgacctg gacgtgaagg     4800

aaaaagtaag atgagaaata aagaaagcct ttgtaaggtg gttttaaaag ccttatatgc     4860

aaacctttta atctgtgttt ctgcaagtgc catccttgta cagtgttaag agggtaacat     4920

gggttacctt tgcaccagct tcagtgttaa gctcaccctg ttctttgaag cacccatgtc     4980

agtattagaa gaataggcag cagttcctta gtttacatat gtttgtgcaa ttattttctg     5040

tacttttttg ttcattaatt ttgtcagtat tacaccaaac tgtttttgca acaaaaaaat     5100

tttttttgca ttcatttaat tttaggtcaa ataacatttt atttatgtgg ctcattttat     5160

atttcctaat tttatttatt tcatactgta gtgtacagta ttatagttct tcaatatata     5220

gatatatttt agtaaaaaag gaacatgacg ttgatcattt gggcaaattt tacgtaaaga     5280

gaagagcatt tattgtgttt tggaacatta attgtgagat gggatttttc aattttatta     5340

ttttattttt gtttttttcc aattactgga aattccaaat ttgggaactt ttgatacgat     5400

cttgtgaaaa cactgtattt tcgactgaaa attccacttt cttcatcttg ttttttagct     5460

aaaaagaggg actgttaaat acaatgtatg ataccatgac aaaaatcttt cctgaattgt     5520

ctttgtaaaa gtattattga attttcaatt tgtaatttct tttgaaaatg accatgctcg     5580

aataaaaatg tagccaaact aagaatgtag ttaatgagtt ctgtactttt agagagtttt     5640

ccttcaatga ccattaacat gtaacatgct ttatgcttat aataatgcta attatgtttt     5700

tttcatataa ttttagttta gcaataattt tgactggtac caataactgt tttttaaaat     5760

tccataccta tgtacagcaa ttttacagct tttctcaact gatcctgatt ccagattgtg     5820

tatttttatg tgaggttata ttattcaaat ttagtctatt tactttacag acatttctac     5880

ttttgcatta cgagtattta gagattatgt gttaaaaatt cacttctctg tccaaggggt     5940

ctttgtgatt tattcaaaaa aaagtctaat ttcaaaaaga cagctattat tcagtgttat     6000

ttataatatg taaccttttt taaaggattg ggatagttta tctcactttt tgaaatgcag     6060

acagtagttt accgtttatc tgaaactaga aggcgtgggt gggagaggaa aagctaaaag     6120

caaatgctaa caaaaataac cgtgattttc taagacagtt tttcagtttt tacaagatga     6180

ccctaatatt cagaatatga atgtattcgt aggttttaca taatgacttt tatcaagaaa     6240

ctagattctg cttcttaaat ctaattgcca agtgaagaat aacagaaaaa acagattacc     6300

ttatcaaatt tacagctctt gaatatacag aactataata tagtagctgt ccatgtattt     6360

tttctacttt agaatcaaag aagaaaagca tcattttgct attaaatttg ctaaaatttt     6420

gagtatgata tttccagttg gcaagaacaa catatttata tttattcctt agccataata     6480

ccactttcct aaatttcaca aaagtcattc tttgcaactt gaaactcaat agaaagtgtg     6540

tatgtgtgtg tgtgtatata tatatatata tacacacaca cacatacaca gaaaggatgt     6600

aatgaagata cagtaatagt tgagcagacc tttttagaaa aacatgtttt tagctctatc     6660

ttcaaacttt ctggcagagg gggtgggggg ggcaggggga ggagtggcat caaaatgcta     6720

tgcctcctgt tatccacagc ctagagtttt tatatttgga aagtttagaa aattctatcc     6780

tcgtttctcc ttctttgaat ggcacaaata aatacactac ataaattttt ctggtttgaa     6840

aggctctagg cgataacttt attaattcaa cctgaaaata tcaagccatt aaattttgtc     6900

cgggtagaat aaatccctgt ggcctctttt aaagcaatgt aggtctctgt tgcccatggg     6960

gcatatctgt gtcccaatcc acaagagata ggaccaacaa acaatgaatg tgcaacctaa     7020

ctctttctcc ttggaaagaa gaaagtgtgc acgaagtaga ggagggtggg cagaccctgc     7080

cttgcccctc ctgttacccc cttctctgtc atttgttcct aactccattt cataggcagg     7140

ctcagaatac ctgagtctga aaatatcagg ataacacttg tgaattgtga caatcactac     7200

aatgtcccat atctgaggag ttttttttaa tgctatttat ccgctggaca cgattgcaca     7260

ttagggctgc ataatcctct aactctaggg aaaaataaaa acttttgatt tgtcttaaga     7320

ttcttctcca aggtcgcaaa caagaaattc ccctccacaa ccaagagatg tgcattttag     7380

taacatcaga tgtgttcttc tgttttatca actacttact cttcccacac gcttagttct     7440

aaatctaacc tttcccccct cgaatagggg gcaggggagg atgaggaaac actggaacaa     7500

ctgaacaccc ctgcccattt tctccaagag ccttttgtat tctagcatat ctgtgcaatc     7560

ttttcttttt tcttcacatg acactgtaag cttaggcctg aaataactgg gaagagagat     7620

gcgtatcaga atttctccgc aagagctaaa caaaacatac atcttcctta gcatgaattg     7680

gactgggggc ggagtgggag ggcttggagg aaaggggaaa gaagggacta tatttgaata     7740

aatatgaata aatgtattag atacttttca caatcagata acttttaaaa aggtcatttt     7800

ttatctttct aataatgtaa gccttaataa aagcaaatct tagtcacaaa tttgaggaga     7860

ctgcccaata ataagtttac atgtatttga actgaaaaat tgttaaccat gcttttgctc     7920

caagatgtgt gaggccattc aggggctgta gggccctgga tatacacaca aacaagtgtg     7980

tgtatatctg gagccccaca cattgtaata aacacagctg catttatttg actatgtgat     8040

cccatgtaca tgtaaaaaca ttcaaacaaa cacactcagc ggatttattt attgtgcaat     8100

ggggcaatta ttcaaataaa catgctcaat gcaattattt gaatctcaca ttgcatgttc     8160

atcaatcata gcactaaaaa aagaggggga aaaaacacca aagaattcac atggggaaaa     8220

aatatatata tgaaaaccac cttattatag attttatagg gcagctgagg ttatggctcc     8280

cttcttaact gtaactcaac tattctgtat tcaatgacat ttgtttctaa tgattaattg     8340

gttcactcac ttgatcatat aatagcaaac tttataaacc tgtattgtgt agagatgtga     8400

aatctctata tttcaagagc agaagagttc tttctagaca ccttacatca agggacactg     8460

gtccaattat tatcgcttat ataagcactc ctataaattc tgaaaaattt tatacatgca     8520

acaaaacatt cctacatttg aagacattaa gaaaaatcac aggtgactca tctgatcatt     8580

ctatatatta ataaatatta tgacatatat gtgaacacat cacaaatcat attggtgtac     8640

caagaggcaa tttatgcctc tcttaagtat gtactgacat aacctaatat actaaaatgg     8700

gaaggggctt ttagtcactg aaatatgcat cgtgtaacaa agatgaagaa aatacatggc     8760

ttgtgcccat cataaaaaaa gattcagact gaaggcttag ctttggtttt ttcaattaaa     8820

ttgttaaact gtgcacagtg attttttttt agaacttgag acatttgtga tgttggctgt     8880

ttaaatcttt gttaccttcg ctgtgaattg aaattgtaca tatttagtaa atcatgcaga     8940

caaaacaaac tttttagaca atatttttat tggagagttt tcttttcctg tatccatgtt     9000

aaaaaaaaaa aagacctcct ttcccaaaat aaaaatgtca atactaaatt taaagaagta     9060

taaaggaatg attgcttcct ttagagcaaa atatttaaat aaacatggag ataattggca     9120

acatgttctt tttgggctag taggctgtgt ccaatttttt gggtctgatg tttcagaggg     9180

cctctgtttc agggttgaag atgatatatt aatctcggaa ttaaacaaat gctattaaat     9240

aac                                                                   9243


<210>  1167
<211>  4657
<212>  DNA
<213>  homo sapiens

<400>  1167
ggggacgggg ggaggggcgg gggtcacgtt acgcggagga cgcgcgggca gcgccgggag       60

aaccgaaccc ctggcggccg cgaccccggc tcccgccccg gccccggccc gacccgccat      120

gacggggctg gaggaccagg agttcgactt cgagttcctc ttcgagttta accagcgcga      180

cgagggcgcc gccgcggccg ccccagaaca ctatggctat gcatcctcca acgtcagccc      240

cgccctgccg ctccccacgg cgcactccac cctgccggcc ccgtgccaca accttcagac      300

ctccacaccg ggcatcatcc cgccggcgga tcacccctcg gggtacggag cagctttgga      360

cggtgggccc gcgggctact tcctctcctc cggccacacc aggcctgatg gggcccctgc      420

cctggagagt cctcgcatcg agataacctc gtgcttgggc ctgtaccaca acaataacca      480

gtttttccac gatgtggagg tggaagacgt cctccctagc tccaaacggt ccccctccac      540

ggccacgctg agtctgccca gcctggaggc ctacagagac ccctcgtgcc tgagcccggc      600

cagcagcctg tcctcccgga gctgcaactc agaggcctcc tcctacgagt ccaactactc      660

gtacccgtac gcgtcccccc agacgtcgcc atggcagtct ccctgcgtgt ctcccaagac      720

cacggacccc gaggagggct ttccccgcgg gctgggggcc tgcacactgc tgggttcccc      780

gcggcactcc ccctccacct cgccccgcgc cagcgtcact gaggagagct ggctgggtgc      840

ccgctcctcc agacccgcgt ccccttgcaa caagaggaag tacagcctca acggccggca      900

gccgccctac tcaccccacc actcgcccac gccgtccccg cacggctccc cgcgggtcag      960

cgtgaccgac gactcgtggt tgggcaacac cacccagtac accagctcgg ccatcgtggc     1020

cgccatcaac gcgctgacca ccgacagcag cctggacctg ggagatggcg tccctgtcaa     1080

gtcccgcaag accaccctgg agcagccgcc ctcagtggcg ctcaaggtgg agcccgtcgg     1140

ggaggacctg ggcagccccc cgcccccggc cgacttcgcg cccgaagact actcctcttt     1200

ccagcacatc aggaagggcg gcttctgcga ccagtacctg gcggtgccgc agcaccccta     1260

ccagtgggcg aagcccaagc ccctgtcccc tacgtcctac atgagcccga ccctgcccgc     1320

cctggactgg cagctgccgt cccactcagg cccgtatgag cttcggattg aggtgcagcc     1380

caagtcccac caccgagccc actacgagac ggagggcagc cggggggccg tgaaggcgtc     1440

ggccggagga caccccatcg tgcagctgca tggctacttg gagaatgagc cgctgatgct     1500

gcagcttttc attgggacgg cggacgaccg cctgctgcgc ccgcacgcct tctaccaggt     1560

gcaccgcatc acagggaaga ccgtgtccac caccagccac gaggccatcc tctccaacac     1620

caaagtcctg gagatcccac tcctgccgga gaacagcatg cgagccgtca ttgactgtgc     1680

cggaatcctg aaactcagaa actccgacat tgaacttcgg aaaggagaga cggacatcgg     1740

gaggaagaac acacgggtac ggctggtgtt ccgcgttcac gtcccgcaac ccagcggccg     1800

cacgctgtcc ctgcaggtgg cctccaaccc catcgaatgc tcccagcgct cagctcagga     1860

gctgcctctg gtggagaagc agagcacgga cagctatccg gtcgtgggcg ggaagaagat     1920

ggtcctgtct ggccacaact tcctgcagga ctccaaggtc attttcgtgg agaaagcccc     1980

agatggccac catgtctggg agatggaagc gaaaactgac cgggacctgt gcaagccgaa     2040

ttctctggtg gttgagatcc cgccatttcg gaatcagagg ataaccagcc ccgttcacgt     2100

cagtttctac gtctgcaacg ggaagagaaa gcgaagccag taccagcgtt tcacctacct     2160

tcccgccaac gttccaatta taaaaacaga acccactgat gattatgagc ctgctccaac     2220

ctgtggaccg gtgagccagg ggttaagtcc tctcccaaga ccatactaca gccagcagct     2280

cgcgatgcca cccgacccca gctcctgcct cgtggccggc ttcccgccct gtccgcagag     2340

aagcaccctg atgccagcgg cccctggcgt gagccccaag ctccacgacc tttctcccgc     2400

tgcctacacc aagggcgttg ccagcccggg ccactgtcac ctcggactcc cgcagccggc     2460

cggagaggcc cccgccgtcc aggacgtgcc caggccagtg gccacgcacc ccggctcgcc     2520

cgggcagcca cccccggccc tgctgccaca gcaggtgagt gcgcctccaa gcagtagctg     2580

cccccctggt ctcgaacact cgctctgccc cagcagcccc tctcctccac tcccgcctgc     2640

cacccaagag ccgacctgcc tgcagccctg cagcccagcg tgcccgcccg ccacgggccg     2700

cccgcagcac ctgccgtcca cggtccgcag ggacgagtct ccgactgccg ggccacggct     2760

gctgccagag gtgcatgagg acggtagtcc taatttggcc cctattcctg taacggtcaa     2820

gcgagagcct gaagagttgg accagttgta cctggatgac gtaaatgaaa taatacgaaa     2880

tgacctctcc agcacgagca cccactccta gttgccacat tggagcactc agttcagcag     2940

gggtatgctg acttcagcag acaaagactt ttgaataaat aaactgaact cacacctggt     3000

accactcaga acctccaact gactgaatgc caggagctga acattaatat gtgcaaagat     3060

tggctctcca acaagaagga aagcagggag gaagggagac cactgtgtca cctggaggag     3120

aagtcatctc atgacaacag aagggaggtg gccgggctga gcacgggaga cccaccgtgc     3180

aggggccttt catgggaacg gcccacacgc agtttgaccc cacgcccagc ccttctggca     3240

cccctggggt tcaatactgg aagtgcctta tttaaccaga ccatcagggc atcatagaat     3300

tgagcattga atttgctact gtaggagtat ttttaggagc agaaactgca aacacatttc     3360

attgtgaggt tttaccctct gtatgaatga agagaacgct ggaaggctgc gagaggactc     3420

tagtatgagt ctccaacatt tggaacgttt cctgggctgt cacgtacact cctgctgcct     3480

tacacagtgc attttagaat cttccagtct gtcatctcag ctcttttgta acatgcttcc     3540

cttgtctgcg cggttgaaac cgtaggcttg ttcatagtcg catgctcgca tctttgtttt     3600

taatctggct tcgaacatag cacaagtaac ttgaatagca catcaatagg ttactggaca     3660

aaagcagaaa aacctgttac aggatagcct gcatttgcat gtgtgtacat atctaggcat     3720

ctatttatgt ataaataata acagagccga cgtgtcctcg cccaggaggg cttccctgtc     3780

agcaataacc ggcatccgtt ttggaacctg cgtctggggc tccagtcgct gctcttgctg     3840

gcgtccatcg ccgcctcgga cggccgtgca ttttctcgtc tcacgcagtt cgaggaggac     3900

cctagaaagc caggagctgt gattgacagt agctgtaggt taccagacgg caacattaga     3960

aagtgattgt aaataacatg caacctaagt gtaatatatt tgttcagtta taagatgatt     4020

gtttcacaga agccttacca ctctctgctt catctaagaa aaccaatacc aaaaacgcca     4080

ctttaatgct cagccctgcg ttgtgtgttt tcagatgagt tactgttaac aggtaggttt     4140

gtgtaggcct tgctgggcac tctgtacaat tagttgctta ttacgtatga ttactcacag     4200

cgatctattg ttccatataa ccaaaaagca tggtttattc attgaaacac ggttgacctg     4260

aactcgtgcc ttaggaatta atgccccctt atggaacctg cctgaattgc acctgcgggt     4320

ggaggctccg gctgtgaagt cactgaacag aacgtcgctg atggagaaag ggctcccgca     4380

gaaggaacgg cctgtaccgt gcgctccggc acaatcgcgt ctcttgtgtc tcactcacgg     4440

aaagaaacaa cctgaaggcc atcccgtcgg tctgcacgta accgtgaaga cgtgtggccg     4500

cgtcccacct gcggctgggt accctgcacc cggcactgta ggagtcacgt gcagcctttc     4560

tcaggggact gtcattgaaa aggaaacgtt tgatgtctgt gtcagctgtc tttgtagtta     4620

ggaaatagat ccaataaagc cgtatttttt tgctgga                              4657


<210>  1168
<211>  4350
<212>  DNA
<213>  homo sapiens

<400>  1168
ggggacgggg ggaggggcgg gggtcacgtt acgcggagga cgcgcgggca gcgccgggag       60

aaccgaaccc ctggcggccg cgaccccggc tcccgccccg gccccggccc gacccgccat      120

gacggggctg gaggaccagg agttcgactt cgagttcctc ttcgagttta accagcgcga      180

cgagggcgcc gccgcggccg ccccagaaca ctatggctat gcatcctcca acgtcagccc      240

cgccctgccg ctccccacgg cgcactccac cctgccggcc ccgtgccaca accttcagac      300

ctccacaccg ggcatcatcc cgccggcgga tcacccctcg gggtacggag cagctttgga      360

cggtgggccc gcgggctact tcctctcctc cggccacacc aggcctgatg gggcccctgc      420

cctggagagt cctcgcatcg agataacctc gtgcttgggc ctgtaccaca acaataacca      480

gtttttccac gatgtggagg tggaagacgt cctccctagc tccaaacggt ccccctccac      540

ggccacgctg agtctgccca gcctggaggc ctacagagac ccctcgtgcc tgagcccggc      600

cagcagcctg tcctcccgga gctgcaactc agaggcctcc tcctacgagt ccaactactc      660

gtacccgtac gcgtcccccc agacgtcgcc atggcagtct ccctgcgtgt ctcccaagac      720

cacggacccc gaggagggct ttccccgcgg gctgggggcc tgcacactgc tgggttcccc      780

gcggcactcc ccctccacct cgccccgcgc cagcgtcact gaggagagct ggctgggtgc      840

ccgctcctcc agacccgcgt ccccttgcaa caagaggaag tacagcctca acggccggca      900

gccgccctac tcaccccacc actcgcccac gccgtccccg cacggctccc cgcgggtcag      960

cgtgaccgac gactcgtggt tgggcaacac cacccagtac accagctcgg ccatcgtggc     1020

cgccatcaac gcgctgacca ccgacagcag cctggacctg ggagatggcg tccctgtcaa     1080

gtcccgcaag accaccctgg agcagccgcc ctcagtggcg ctcaaggtgg agcccgtcgg     1140

ggaggacctg ggcagccccc cgcccccggc cgacttcgcg cccgaagact actcctcttt     1200

ccagcacatc aggaagggcg gcttctgcga ccagtacctg gcggtgccgc agcaccccta     1260

ccagtgggcg aagcccaagc ccctgtcccc tacgtcctac atgagcccga ccctgcccgc     1320

cctggactgg cagctgccgt cccactcagg cccgtatgag cttcggattg aggtgcagcc     1380

caagtcccac caccgagccc actacgagac ggagggcagc cggggggccg tgaaggcgtc     1440

ggccggagga caccccatcg tgcagctgca tggctacttg gagaatgagc cgctgatgct     1500

gcagcttttc attgggacgg cggacgaccg cctgctgcgc ccgcacgcct tctaccaggt     1560

gcaccgcatc acagggaaga ccgtgtccac caccagccac gaggccatcc tctccaacac     1620

caaagtcctg gagatcccac tcctgccgga gaacagcatg cgagccgtca ttgactgtgc     1680

cggaatcctg aaactcagaa actccgacat tgaacttcgg aaaggagaga cggacatcgg     1740

gaggaagaac acacgggtac ggctggtgtt ccgcgttcac gtcccgcaac ccagcggccg     1800

cacgctgtcc ctgcaggtgg cctccaaccc catcgaatgc tcccagcgct cagctcagga     1860

gctgcctctg gtggagaagc agagcacgga cagctatccg gtcgtgggcg ggaagaagat     1920

ggtcctgtct ggccacaact tcctgcagga ctccaaggtc attttcgtgg agaaagcccc     1980

agatggccac catgtctggg agatggaagc gaaaactgac cgggacctgt gcaagccgaa     2040

ttctctggtg gttgagatcc cgccatttcg gaatcagagg ataaccagcc ccgttcacgt     2100

cagtttctac gtctgcaacg ggaagagaaa gcgaagccag taccagcgtt tcacctacct     2160

tcccgccaac gttccaatta taaaaacaga acccactgat gattatgagc ctgctccaac     2220

ctgtggaccg gtgagccagg ggttaagtcc tctcccaaga ccatactaca gccagcagct     2280

cgcgatgcca cccgacccca gctcctgcct cgtggccggc ttcccgccct gtccgcagag     2340

aagcaccctg atgccagcgg cccctggcgt gagccccaag ctccacgacc tttctcccgc     2400

tgcctacacc aagggcgttg ccagcccggg ccactgtcac ctcggactcc cgcagccggc     2460

cggagaggcc cccgccgtcc aggacgtgcc caggccagtg gccacgcacc ccggctcgcc     2520

cgggcagcca cccccggccc tgctgccaca gcagtaaatg aaataatacg aaatgacctc     2580

tccagcacga gcacccactc ctagttgcca cattggagca ctcagttcag caggggtatg     2640

ctgacttcag cagacaaaga cttttgaata aataaactga actcacacct ggtaccactc     2700

agaacctcca actgactgaa tgccaggagc tgaacattaa tatgtgcaaa gattggctct     2760

ccaacaagaa ggaaagcagg gaggaaggga gaccactgtg tcacctggag gagaagtcat     2820

ctcatgacaa cagaagggag gtggccgggc tgagcacggg agacccaccg tgcaggggcc     2880

tttcatggga acggcccaca cgcagtttga ccccacgccc agcccttctg gcacccctgg     2940

ggttcaatac tggaagtgcc ttatttaacc agaccatcag ggcatcatag aattgagcat     3000

tgaatttgct actgtaggag tatttttagg agcagaaact gcaaacacat ttcattgtga     3060

ggttttaccc tctgtatgaa tgaagagaac gctggaaggc tgcgagagga ctctagtatg     3120

agtctccaac atttggaacg tttcctgggc tgtcacgtac actcctgctg ccttacacag     3180

tgcattttag aatcttccag tctgtcatct cagctctttt gtaacatgct tcccttgtct     3240

gcgcggttga aaccgtaggc ttgttcatag tcgcatgctc gcatctttgt ttttaatctg     3300

gcttcgaaca tagcacaagt aacttgaata gcacatcaat aggttactgg acaaaagcag     3360

aaaaacctgt tacaggatag cctgcatttg catgtgtgta catatctagg catctattta     3420

tgtataaata ataacagagc cgacgtgtcc tcgcccagga gggcttccct gtcagcaata     3480

accggcatcc gttttggaac ctgcgtctgg ggctccagtc gctgctcttg ctggcgtcca     3540

tcgccgcctc ggacggccgt gcattttctc gtctcacgca gttcgaggag gaccctagaa     3600

agccaggagc tgtgattgac agtagctgta ggttaccaga cggcaacatt agaaagtgat     3660

tgtaaataac atgcaaccta agtgtaatat atttgttcag ttataagatg attgtttcac     3720

agaagcctta ccactctctg cttcatctaa gaaaaccaat accaaaaacg ccactttaat     3780

gctcagccct gcgttgtgtg ttttcagatg agttactgtt aacaggtagg tttgtgtagg     3840

ccttgctggg cactctgtac aattagttgc ttattacgta tgattactca cagcgatcta     3900

ttgttccata taaccaaaaa gcatggttta ttcattgaaa cacggttgac ctgaactcgt     3960

gccttaggaa ttaatgcccc cttatggaac ctgcctgaat tgcacctgcg ggtggaggct     4020

ccggctgtga agtcactgaa cagaacgtcg ctgatggaga aagggctccc gcagaaggaa     4080

cggcctgtac cgtgcgctcc ggcacaatcg cgtctcttgt gtctcactca cggaaagaaa     4140

caacctgaag gccatcccgt cggtctgcac gtaaccgtga agacgtgtgg ccgcgtccca     4200

cctgcggctg ggtaccctgc acccggcact gtaggagtca cgtgcagcct ttctcagggg     4260

actgtcattg aaaaggaaac gtttgatgtc tgtgtcagct gtctttgtag ttaggaaata     4320

gatccaataa agccgtattt ttttgctgga                                      4350


<210>  1169
<211>  4839
<212>  DNA
<213>  homo sapiens

<400>  1169
agcggccttt ctctgttcgc gatgtgacgt aacgcgcctg cggactgggc ccagcttgtc       60

ctctatgact tacccagaag gcaacgcttc tctttctggt caaaatggct ggtaagcagg      120

ccgtttcagc atcaggcaag tggctggatg gtattcgaaa atggtattac aatgctgcag      180

gattcaataa actggggtta atgcgagatg atacaatata cgaggatgaa gatgtaaaag      240

aagccataag aagacttcct gagaaccttt ataatgacag gatgtttcgc attaagaggg      300

cactggacct gaacttgaag catcagatct tgcctaaaga gcagtggacc aaatatgaag      360

aggaaaattt ctaccttgaa ccgtatctga aagaggttat tcgggaaaga aaagaaagag      420

aagaatgggc aaagaagtaa tcatgtagtt gaagtctgtg gatgcagctg ttatgaagat      480

ggttaaactt gaaacaaaca attttaagaa ttatttggtc tgaagatgtt ttactttaaa      540

taaatgtcta ttgtaatggc tggagttttt gaattccaaa ccttatactg aataactact      600

gaatcccttt actgttaaat ttttttccaa actttcaaga tatatttagt tgtgtttaac      660

tgctacttgg agctcagaag ccactttatc agttttcctc actggttgga tagcctatca      720

gtttatggaa ggatataact tccgtaagtt acatccttat ggaagctact gaataaaaga      780

agggggtatg caccccctag tttgccaaga ttgagaaata gcctcttcac tggtatgcaa      840

acagatttga ttttgcatcc tatcatttaa aaagaaatta tgtctgcacc ccaacatagg      900

catacttaag taatatacat actcctgtgc taacatgtat actagaaaac aaaaagatgt      960

tagaaaaata aaagtataaa gacaaatcat actgtcccca tatcccagtg acttttccac     1020

tttggaaatg attgttatga agtttaaggg ttggatacta gtcagttaaa agttttaaga     1080

ttatagggta atttttaaaa atataaatta gaatcattgg caaggcatgg tggctcatgc     1140

ctgtaatccc agcactttgg gaggccgagg cgggcgggtc acctgaagtc aggaatttga     1200

gaccagcctg gccaacatgg tgaaaccctg tctctactaa aaatacaaaa aattagctag     1260

gcgtgatggt aggcacctgt aatcccagct actcgggagg ctgagggagg agaattgctt     1320

gaccccagga ggtggaggtt gcagtgagcc tagatcacac cactgcactt cagcctgagc     1380

gacattgact gtctcaaaaa aaaaattagg attattcaat gttgtcatca tttccactcc     1440

taaattctga aatgctttct ttggtagagg tgagagtgtg gagccacagc tagtagagaa     1500

ggaacagtag gacctgcagc ctccctggtt ttccaggaca agtcattgct gtgtgtggca     1560

ggaatgcctt acctcaaata acaaaacagt gtgaaaaacg aatttgtgtt acatttaaag     1620

tttgtaaagc aatgagaaat gtgtgtatca taaagagcat ctttaaattt ttgctaaaat     1680

attagcctct taaattctct aggaaccccc tcccccgctt ttttttttcc tttcgctggt     1740

cgttattttt ctaaacctat cctgaaatca tgtcaatttt cttttgtatg gttgaagaca     1800

actagatcac ttgataatgg ttttgctcag gtcacattgt gacaaggttt taatgtagtc     1860

ctactttgca gaaggaggcc aagaagatgg gctgtctaga acccccttta aaagcatttg     1920

tctattcaga aaattttcct gagtagatct ctgcaaaggc tcttttaata gtgatttcaa     1980

gatcacgttt gcaggactct ggtctattcg ttcagacgtc tactgtgcac aattacaagg     2040

agactacaac tgaggcatct caaagagcac tgtcaaggtg tgtagggagc cgggtgggtg     2100

gagggaggct gggctctgac cctagaaacc atgcttatga atgctgttaa tgtttaaagc     2160

aagcctaagg gcactgctga aggacagggg aacaaataga actgaccaag actgaggtat     2220

aacaggaacc cccaggctat ccacctgctc aaggtaaagt gtggtattac ataaggcaac     2280

ctctgatttt gtaagagttc ttcctaaagc caaagtgtat gcctattcta tgtttccaga     2340

ttacttcatt cttctaaatg agaacaagtg tgcaaaagtt ctttgaacac tagatcaatg     2400

ttttgtgttc attataaatt atggttatcg tcctgcttgt tatgaagact aagaaagtag     2460

atctagtatt tggctcacac aggtgaatgg gtgagaattt gttaatccat cagtgaagtc     2520

ctttcatttg aaagagaggg cctttctatt atcaaaagcc gtcctgtgtg gaaaatcacc     2580

atgagagtgc ctgaaacaca ggcactctgc attgtcctgt agaccaaatc tacattgtcc     2640

tgtagtctgg tctacattgt cctgtagacc gaatggtaga gtgattcaga gctaattctg     2700

ggttagactg cacaggtctg aatctatttg ctcactgtgt agtgctttag gaatacaatt     2760

taacctctcc gtgcttcagt ttgtttgtcc ctaagataga gctaatgata gaaacctact     2820

tcacccagtt gtgaaaatta actgactgca tgtcaagcac taacagtttc tggcatatag     2880

tatgcataat gtaaattatg tgctgagaag cgagaaagaa taacttggga aaacgctgaa     2940

tatcatcaat gtcgaatagc taaccagtag ctaaggtcca aggtctcctc tcttccttct     3000

atgtggcact cttgtttctg gttcatctac tccccttggg tgtcacctcc ttgagtgaag     3060

tacctgctgg agatgagaag agtggaactg gatctgcatg acagctttga ttaggatgga     3120

gctaagactt ggctatctcc ctgttttgtg ttttggatgg gtgacatttt aaaactgcca     3180

atattcaaat cctgctaatt tgctttgtac agtttaaaat gtttgatatc ttttgttgtt     3240

taaagtttga gattggtttt gaatatacag ttttcctaca tcttgaagaa agttatgttt     3300

gtttactctg aagtggtcta tgttctgttt gtttgtttta ctatactttg caaaaaaaca     3360

gatggctggc ttatgttcac tgttgtagtg cactacctag tatcacttgg ccttcctgtt     3420

gtcaagatgt aggaagcagc gtaagggatg tcgggccttc agacccccaa ttgccagctg     3480

tggtcctagt tccagattgc atggaaatat ttgataacat tcctgcactg agttatcatg     3540

gtctgaatat ttatgtgacg ctctacgagt ggtaccaaaa tgttagtgat ggagttttta     3600

ctaatggcac cttttcctgt ttttaaattc tagaatctta ataaatccaa agtgtacatt     3660

ttggtagtga tttcatttag ttatttactt taaggactcc cttttcaagc attaactctg     3720

cactaatttt gacttatgaa aagattcagc agtaagaata aaaactgggc caaagcccaa     3780

agtaataatc cttcacaaat aggatggagt tttaaaaata tgggcatcct gtgtgtagct     3840

ttgaaaataa ccaaactact tggaattaaa aagttaggtg aacatgaaga ttgtcataac     3900

caaatccttg acagcttgat ggatgaagag cagatgggtt tatggtgtat gggaggaagc     3960

atggatttta ggagggacag tatcagagag ggatggttag aaagtgagta agacaggttg     4020

ctctttggaa aacaaggaaa atccctttat tagaacaagg catgaaattc tgccactagg     4080

tggcgatgcc ctataacttt acaacttagt gtacatcaca cgagcactat ggaagatttc     4140

tccattctgc gccccaccaa ctccctcccc tccttcattt ttcaggatga caacacctta     4200

gaggtttatg gccatcagga gaatttacta ctaagctata tactgatgta atgaaatcta     4260

atatatgttg tgcaatgaat tatgagatgt tatttagttt caggatttta ttacttcaat     4320

cagttatgac catatttcct tttatatgat tgctcactct ttaaacatac cagatgactg     4380

tataaggaac acctaataaa gtctatagat gttaaaatat tttaaatgtt ttaatttata     4440

tgccataatt tgtttacatt ctggttatac tggcgttcat attaaaagcc ataacatgtt     4500

agaatctgag atctcaggtc ggatagtgcc tctaagttat attttgctaa gaaattttat     4560

tgtattagca attgagcaag aaagaagaac tgaatcatta tacggtggtt aatttttagc     4620

atagatgtca gaaagcctgt taatattcca gaggcttatg ataaactatt taaattgtca     4680

ttctggattc tgattatatc tcctacaaag aaagagtgta ttatttattg aactttttgt     4740

ttgaatacat gtgcctattt ttgcataaat gtaaaaatgt aattttaaaa taaacccctg     4800

aaaacttctg gtaacattaa aaaaaaaaaa aaaaaaaaa                            4839


<210>  1170
<211>  8450
<212>  DNA
<213>  homo sapiens

<400>  1170
gctcagaaac tgccagccca gaccacaggc tcagaggctg aagcaggagg aaggaaggac       60

tggaaggaaa aagagacagg ttagagggaa agaggcttgg gaagaaaaca gcagaaaaga      120

aactgctcat tacacttaca gagaggcaag taacggtgga gatgaggaca gagggaacca      180

agactctgaa agacaaaaaa tacaaataga gcgaaagagg aaaaaaatgt caagaagaac      240

atccatccgg agaaatgaag agaatgaaag ttttaagctg cagagccgtt ctgtgctttt      300

ccggcacaaa attatatcgc tgattttaag cccttttgca tttgccagcc gttgacatta      360

agaggcatgt ttaacggtgc caacagcatc tccttttcct tctcctcttc ctcttcttct      420

tcttcctcct cctcctcctc tttttcctcc tcctcgttct cctcccatca gcaagaagac      480

aaaccgagga cagtcttgaa atatcgaaat ttcctctttg ggatttgcca gcgccaagac      540

tgtcggaata aaggacgctg actattgtat tattgttatt ttattaatta gtcagtggaa      600

agattacaga tgaggaaagg ggacgcctgt cacccttcct gtgctaagat ttaaaaaaaa      660

atgaggctgg attgcgggaa gctctaaaat gaagcaaaag gagtaagatt tttaaagaca      720

gaaagccaca ggagccccca cgtagcgcac ttttatttgt attttttcag attttttttt      780

gtttcgtggt ggtgggggag gtgattgggt ggctgactgg ctgcgggaag ctacttcctt      840

tccttttgga gatgattgtg ctattattgt ttgccttgct ctggatggtg gaaggagtct      900

tttcccagct tcactacacg gtacaggagg agcaggaaca tggcactttc gtggggaata      960

tcgctgaaga tctgggtctg gacattacaa aactttcggc tcgcgggttt cagacggtgc     1020

ccaactcaag gaccccttac ttagacctca acctggagac aggggtgctg tacgtgaacg     1080

agaaaataga ccgcgaacaa atctgcaaac agagcccctc ctgtgtcctg cacctggagg     1140

tctttctgga gaaccccctg gagctgttcc aggtggagat cgaggtgctg gacattaatg     1200

acaacccccc ctctttcccg gagccagacc tgacggtgga aatctctgag agcgccacgc     1260

caggcactcg cttccccttg gagagcgcat tcgacccaga cgtgggcacc aactccttgc     1320

gcgactacga gatcaccccc aacagctact tctccctgga cgtgcagacc cagggggatg     1380

gcaaccgatt cgctgagctg gtgctggaga agccactgga ccgagagcag caagcggtgc     1440

accgctacgt gctgaccgcg gtggacggag gaggtggggg aggagtagga gaaggagggg     1500

gaggtggcgg gggagcaggc ctgccccccc agcagcagcg caccggcacg gccctactca     1560

ccatccgagt gctggactcc aatgacaatg tgcccgcttt cgaccaaccc gtctacactg     1620

tgtccctacc agagaactct cccccaggca ctctcgtgat ccagctcaac gccaccgacc     1680

cggacgaggg ccagaacggt gaggtcgtgt actccttcag cagccacatt tcgccccggg     1740

cgcgggagct tttcggactc tcgccgcgca ctggcagact ggaggtaagc ggcgagttgg     1800

actatgaaga gagcccagtg taccaagtgt acgtgcaagc caaggacctg ggccccaacg     1860

ccgtgcctgc gcactgcaag gtgctagtgc gagtactgga tgctaatgac aacgcgccag     1920

agatcagctt cagcaccgtg aaggaagcgg tgagtgaggg cgcggcgccc ggcactgtgg     1980

tggccctttt cagcgtgact gaccgcgact cagaggagaa tgggcaggtg cagtgcgagc     2040

tactgggaga cgtgcctttc cgcctcaagt cttcctttaa gaattactac accatcgtta     2100

ccgaagcccc cctggaccga gaggcggggg actcctacac cctgactgta gtggctcggg     2160

accggggcga gcctgcgctc tccaccagta agtcgatcca ggtacaagtg tcggatgtga     2220

acgacaacgc gccgcgtttc agccagccgg tctacgacgt gtatgtgact gaaaacaacg     2280

tgcctggcgc ctacatctac gcggtgagcg ccaccgaccg ggatgagggc gccaacgccc     2340

agcttgccta ctctatcctc gagtgccaga tccagggcat gagcgtcttc acctacgttt     2400

ctatcaactc tgagaacggc tacttgtacg ccctgcgctc cttcgactat gagcagctga     2460

aggacttcag ttttcaggtg gaagcccggg acgctggcag cccccaggcg ctggctggta     2520

acgccactgt caacatcctc atagtggatc aaaatgacaa cgcccctgcc atcgtggcgc     2580

ctctaccagg gcgcaacggg actccagcgc gtgaggtgct gccccgctcg gcggagccgg     2640

gttacctgct cacccgcgtg gccgccgtgg acgcggacga cggcgagaac gcccggctca     2700

cttacagcat cgtgcgtggc aacgaaatga acctctttcg catggactgg cgcaccgggg     2760

agctgcgcac agcacgccga gtcccggcca agcgcgaccc ccagcggcct tatgagctgg     2820

tgatcgaggt gcgcgaccat gggcagccgc ccctttcctc caccgccacc ctggtggttc     2880

agctggtgga tggcgccgtg gagccccagg gcgggggcgg gagcggaggc ggagggtcag     2940

gagagcacca gcgccccagt cgctctggcg gcggggaaac ctcgctagac ctcaccctca     3000

tcctcatcat cgcgttgggc tcggtgtcct tcatcttcct gctggccatg atcgtgctgg     3060

ccgtgcgttg ccaaaaagag aagaagctca acatctatac ttgtctggcc agcgattgct     3120

gcctctgctg ctgctgctgc ggtggcggag gttcgacctg ctgtggccgc caagcccggg     3180

cgcgcaagaa gaaactcagc aagtcagaca tcatgctggt gcagagctcc aatgtaccca     3240

gtaacccggc ccaggtgccg atagaggagt ccgggggctt tggctcccac caccacaacc     3300

agaattactg ctatcaggta tgcctgaccc ctgagtccgc caagaccgac ctgatgtttc     3360

ttaagccctg cagcccttcg cggagtacgg acactgagca caacccctgc ggggccatcg     3420

tcaccggtta caccgaccag cagcctgata tcatctccaa cggaagcatt ttgtccaacg     3480

agactaaaca ccagcgagca gagctcagct atctagttga cagacctcgc cgagttaaca     3540

gttctgcatt ccaggaagcc gacatagtaa gctctaagga cagtggtcat ggagacagtg     3600

aacagggaga tagtgatcat gatgccacca accgtgccca gtcagctggt atggatctct     3660

tctccaattg cactgaggaa tgtaaagctc tgggccactc agatcggtgc tggatgcctt     3720

cttttgtccc ttctgatgga cgccaggctg ctgattatcg cagcaatctg catgttcctg     3780

gcatggactc tgttccagac actgaggtgt ttgaaactcc agaagcccag cctggggcag     3840

agcggtcctt ttccaccttt ggcaaagaga aggcccttca cagcactctg gagaggaagg     3900

agctggatgg actgctgact aatacgcgag cgccttacaa accaccatat ttgacacgga     3960

aaaggatatg ctagtcaatt ctacaggact tacctgaagc agcatgattt gcacaaagtc     4020

gaccaacaaa agcatcaact tttcaacttc attatcttgg ccatccagtt agtcatgtgt     4080

aactgagtat tagatttcgg atggagtcat catggccaat tataggacct aattgctctc     4140

agcaggcctg agaaatgagt tgaaatgtgc agaactgtag aaactttaga ggcaacagat     4200

tttgcctccc cgatcagtgt gtgcctgttt acagcactat ctatctttct ctctccaaat     4260

gtcactgagc cctttagatg tttatattca ccacgagaag ccagtcataa agataaagga     4320

aatttgtgca ttataaatgc aatatcactg ttttaaactt gactgtttta tattattttt     4380

gtgtgatcaa gtgttccgca agctattcca actttacaag agaaattgtg attatgttct     4440

tttcacctgt gggttataaa aaatgttgta ttctgaagac ccacaaaata tcaaagacat     4500

tctgtagttt atacaccgtg ttgcaaagtg tttactgtac tatttcaaag cttctaaata     4560

aatataaaat atatatatta tattatataa ttttcctaaa atgtggtaca actcagttgg     4620

tttttaaatg gatgcataca gtccacatca tacaataaaa taaaaggtaa ttcagggtcc     4680

caaagacaaa cttactaaga aaaaatcatt aatagttttc tcccaatttc catatcttac     4740

tcaaccgtgt ttttccttgt ttaaaagaaa atgatgctct aagctacaaa attttgtcaa     4800

aaactcatat tgaattttca atgccaaaga tgtagctatt gatgttatca gacagagcac     4860

tgactatgta ctatcaaact atctaacaat ctgcataagt ctgattctat ttctatgact     4920

ttgaatttag aatcacttaa agcttttata aagaatcgat aaattcacct gtatttgttg     4980

ttagaaaaaa actgggtgtc tgtacatttt gtggtgtaaa atatgtaatt gaagattact     5040

attttaagaa gtcatcagtc atatcactca cacagaattt tattttacat agttttgtga     5100

cttaattaca catgaatata aaatctataa ttctatatga atatatagag atatagaaac     5160

atctgaactg gtaaagaata actataaaat atgaaagctc taaatttaaa ataaatttag     5220

agatagaatc atggtacatt attgtttcag tattccatgt gaaaatttta tagcttaaat     5280

gtagtcagtg tttgattaat gaaaaaattc ttcatgagtc agccttcaaa agttaagctt     5340

gccttttact tttatgtcaa caatattaat tattaaattt agtaagacgc actttccttt     5400

cttttatata ttttttctac tgttgtgtat gccttgttag aacacattcg agagaggaaa     5460

aaaatcagag aatataagat aatctttcaa gcaaaaaaca gaattgtcac agctcccctc     5520

gccctctaaa ctatgatatc aaaacatcat atcaaagctt caacattata tcaaaatgtt     5580

tgcccagttc aaattagaaa cctgttttga aatactttcc ttaattttta actgatctta     5640

tattcaatga cagtttgagc tgcactgtgt tattaaagaa tagactaaaa cttaacattt     5700

gacaaatgtt cttcatcaaa ttttatgtaa cttaagtgga aatttttccc tagatttaac     5760

tttaaaatac atatatatac acacacacac acacacacac acacacacac ttaggtcctg     5820

atatgtacat ttagagtgat atattggtat cactcatttg actgttatca aattagatat     5880

taatatatca tattccaatc agttcatata tcaaaataat gtatgtaatg ttccagcctt     5940

ttgaagtctc tttaaacata tatgaagcta acagatcata tgtaatacaa aaagcacata     6000

aattcactaa gtgcagcagt aacattttct taaactttgg cattactaca ttaatatttt     6060

gaatgataga ctattttagt aaggaaatgt ttatacataa tttaactgga aaaaagtctg     6120

tttgttccaa ctcttttttt tagcaagaaa atgattttct tgttgagtca ctctgcttta     6180

attaaaatgt ttcacgcatc attttgcaat catgggtgaa tatccacatc catcttcctt     6240

actgcatgca ttgaaaataa gattatactc acttcatgta tagtaattat attgtcattt     6300

acctcaaaga cattttcttt aattatttaa ccttttatat cattgtatat aatctccttt     6360

gaaccaactt ttttattata tatttgtgta ttagttattt tcatatatcc taggaactag     6420

ttatactaac ttacatttta gttatcatca atctacaaaa ccaaaaccag aacttcttcc     6480

taatttgcgg gacaaataga attgtttaag gataaaatgc tacattatta ggtcattaat     6540

caacttatct gttgcatcca aagtaaatta gaagttacaa cagagtaagg atatgattct     6600

tgtaagttgg ttaaaatgtt ttcttccaat gagggggact ataaaatgga aagtgcaacc     6660

aacaaataat gaaggtttct aattaagcat ttactagatt aatatatcaa ggaattttag     6720

gataggtttt ctctttaatc tggtcattct aatatccaat cttacataat tttatataca     6780

tcaaagaata atatccatcg tattagacag tatttcgtca ataaattatt tcagaaaaaa     6840

aaatcatgtc atttactcct tgttaacatg gttagtttta gagcagtcaa agtcaaaaaa     6900

aatttcctgt ggaaacagtg tcttaatgtt tcaaaggtat gtcaaaagac aatttttaga     6960

aaatatttca tccacatgta gaattctaat ttttaacgtg tgaacatagt ttggtgaaat     7020

catcttaaat caaatttaaa tatcacatca gaattacttc acagatataa tagcgtcaat     7080

gatatatgta tcatcttttc ttggcaaata ttaaggaaat atgtgtattt tattttttaa     7140

agatattaaa tgcactgcct ttatcaaaca ttgcaaatta agaactatag tagaatattt     7200

aaatatttta atttctcatt gttttatttg ttaattggat tgtaatttgc catcagattc     7260

tctgtattat agaagctatc ttgcttcttc aataagagga ggaaaaagaa tctcacaatt     7320

cccaatataa tctttaacaa ctgtacgtta attgtaccat tttaccttct aaacattatt     7380

tactggagct cagttagtct ttaaaacaat tactcaggca gagtgtggca aaagttcagc     7440

aagatcaaga aaagtattta agttattgac tgatcatagc actgttattt gtcattgcat     7500

gtgtttttcc ccctcatgtt tctatgtgtg ctattgatac ccaaggaact caaaaatact     7560

taaaatattg gtatacttga tgatttttct gaaaatctta tatttttcat attacaaatt     7620

cttgagttct ttatcttttt caagtctaat tttgtagtgg taaaggcttt gcacttaaca     7680

tccttttgtg ttccttttta acaaggaaaa acagaaaata atggaattcc atatttttta     7740

caccatggag tagtaaaatt attttatata ttgttagtac ttcaacaaac atccctctgc     7800

taagtcagac aaaatcctta tacagtaatt tgtgaaactg ttcagtagag tattcttttc     7860

ttcaaatctt ggcataggtt ttagattata gcattctgta tgaatgcagg tagatgggtg     7920

ccgccagagt attgcaggca ataatacgac taaaattcta atacttttag tgtgcatgcg     7980

tgtatttcta atcactgtta ttttttaagt atttgtaaaa ttagaaaaat tgcttttatt     8040

tcttgaaaag ttgtcacatg cttagtttga agttttactc tccagatgtt tttgagttgc     8100

ataaaaatct tgcattcatc attcaaaaaa tactaaattt cacatgagac tcaaaaattt     8160

ctgaatgatg gaactcagac ttccaataca ttcatacatg ctagagctga aagtaagcag     8220

ggaatttcag ctctaaacac atttttgaga cagttatctg tgagtgaaaa cagggtatta     8280

taacaaaaga tgagtttcaa tcttaactac agtgtttgtt actgtgaatg ctataataat     8340

acataagtaa aatgagtgta aatgtaataa attattttat actgctgtat acatatgaaa     8400

taaataaaac taggatacat attaaaaaaa aaaaaaaaaa aaaaaaaaaa                8450


<210>  1171
<211>  4152
<212>  DNA
<213>  homo sapiens

<400>  1171
gagaagtgat ccagacctct tagaagttgg gttggggctg ccttatgggt ggacagggat       60

ctctagggaa cctcacaccc atttccccca gaagcaaaag agtaaattct attattgcca      120

accaaccagg acttttccat gccagacatc ctgccatgag gaaatttcag agcgaggacg      180

cccagcatgc cgcccttctg taggaatgca aagttaggcc tcctttcttt cctgatttgt      240

gctggaagga gcttattacc tttggggaag aatgcctttt ggttagaaag aattgaaaat      300

aataataccc tctgggaaaa ggctcaaagt cagaaaatga gatacaagac atccttggtg      360

atgaggaaac gattacggct ttaccgaaac actcttaaag agtcaagtag cagctctgga      420

caccatggcc cccagctcac cgccgcctcc agcccctcgg tgttcccggg cctccacgag      480

gagcctcccc aggcctcccc cagccgtcct ttgaatggac tcctgcgtct ggggctccct      540

ggagacatgt acgcgcggcc ggagcccttc ccgccagggc ctgcggcccg cagcgacgcc      600

ctggcagctg ccgcagccct gcatggctac gggggcatga acctgacggt gaacctcgct      660

gcgccccacg gtcctggcgc tttcttccgc tacatgcgcc agcccatcaa acaggagctc      720

atctgcaagt ggctggcggc cgacggcacc gcgaccccga gcctctgctc caaaactttc      780

agcaccatgc acgagctggt cacgcacgtc accgtggagc acgtcggcgg cccggaacag      840

gccaaccaca tttgcttctg ggaggagtgt ccgcgccagg gaaagccctt caaagccaaa      900

tacaaacttg taaatcacat ccgcgtgcac acgggcgaga agcccttccc ttgtcctttc      960

ccggggtgtg ggaaggtctt tgctagatca gaaaatctca aaatacacaa acgaactcac     1020

acaggcgaga agcccttcag atgcgagttc gagggctgcg agcggcgctt cgccaacagc     1080

agcgaccgta agaagcattc gcacgtgcac actagcgaca agccatacac gtgcaaggtg     1140

cggggctgcg acaagtgcta cacgcacccc agctcgctgc gtaagcacat gaaggtgcac     1200

gggcgctcgc cgccgcccag ctctggctac gattcggcta caccgtctgc cctcgtgtcg     1260

ccctcgtcgg actgcggcca caagtcccag gtggcctcct cggcggcggt ggcggcgcgt     1320

accgccgact tgagcgaatg atgtccaccg cgttgctcgc aaggtaatct cgctccgcgc     1380

agctgagcgc cccgcatctc gcgcctgcta catcaaaggg cccgcgcaca aagcagtgtt     1440

tcttcgccac ggtgcatctt catggtaagt taggatttct atggcaatgt gcaagtcgca     1500

ctgaaatcct gaaaggccaa gcctggagcc cgtccaggct tttcattaag gacataatat     1560

ttacgtctaa cagacctttt ttcttgtgta tacaagtata tatttttgtt tgacgcggac     1620

taaatcattt tcatttaatt tccggtaaac aaaacccacg cgaatgggca cttgtacccg     1680

atcataataa aaatggataa taatgtgaag gaagaaaaga gccgcttgaa tcgccgctca     1740

gccccctttg tttctgcttt ctgcggtgat cagagggcgc gtttgggttt gatggcgagt     1800

ttctaaaggc gaggaaatgg tttgtaagag gggaaagaaa aggagaaagg tctaatcaag     1860

ctcgggttgt tcaaagagtc gggttttggg gttgaaagtg tgagtttgac ggtgcatcag     1920

catgccgcgt taggctcgcc atggaaatac gcgcggggag cggccgcttc aaaggcggca     1980

cacttcacta cagacactct attaagatac atttgcgctg acctttgctt tcacgccatt     2040

taatactgtc actgcgctct ccagtatata cttcctttct agaacccgac ttgcccacgt     2100

ttaggggttc actctgcacc ctgatgtggg aggctttggc gcaggggaca ctttcaggaa     2160

agggaggagc acaaggactc tgtgcatctt gactgcaccc caaagaggct ccaggatcag     2220

gagtgaaaga ttttaaagca gcctccgaag cttaacaaat gagcattcca agctcagttt     2280

tgtgcaaatc gcctttctga ctcttgagta ggatggaggc ttaaatttaa tggcgacttg     2340

gggggaaggg agccaccctg ggggagtctg aggagttcag actgtgccct tgggaatttc     2400

cactctggct ttccgtgcca ctcttcttcc tttccatccc aaaagtctct tgcggcccct     2460

gaaacttgtt tctttctaag gcagggtgtg tggtaccctt aggcctggac tagtcctaga     2520

tgcaaactca agagcccaag gccaagggga tgtggggaag atggcaggaa agttagaagt     2580

ccatgttccc ttaattgtct tgttgtttat tttatccaag taccccagtg aataggggaa     2640

aaataaacac agtgaaaaaa aaaatcaaac agtggagtct tctttagtgc cagtccttgt     2700

ggttgaataa aaaggatggt ccgctttcta ttgagctgag aaatctttga agtgggagtt     2760

attatctgag acattcctgc ttgtcgtcct aacaacgctg atgaaacgta aaaggttctt     2820

tgtcagcgat ttgttctcct ctctgtcaaa ctccctctgc cccgttagtt tcaaaccgtt     2880

tctaaagaga taaaaatcaa acttctttta aaacaatatc cacacactgc atcaatacat     2940

aactttaggt ctaagtcttg ctaagggata aacaaaagca atgcctagac atcagggtca     3000

gggcctggtc tggtgaagta tgcagaagtt ggggggccct cgggacaagc tttgggacat     3060

gaggaaaaga atgcagagag ggtgcaagca gaatacatac cctaagtcca taattgtgtt     3120

tctgcttctt tctgctctgg tttgcattca atcagcccaa gttgggtcac atagatgggt     3180

ttcctttggg tacccctcag gctcctaata ttcttgccca ggatccttgg aacttaagaa     3240

tgcagccaag caattgttaa tatctcctgc tccttcaaag ccacctctgc taaaaataga     3300

cccattgtgt gtttcttctc actagcagca atcaacaagc cctttctgcc gttaataaga     3360

aggagaatag ctgaaggaga gagatatttt attaatttcc tgtttccttc agaatcttgg     3420

caattgaagt ttagaaggtt tggtctacaa cacagtgatc gaaaatgcat gtaaatgccc     3480

atccttccct tcattcacgt gtgaagttgt tcattttata ttgtgcccag caaagaaact     3540

ttcacccagt tcaggtttcc ccaaaactcc tgtggtggtt ttaaaggtgg tttaaataaa     3600

taaggatgtg ctggtccccc tactctgtgt gtgctgaata aatggcttgt aaagaagttt     3660

ttccaagctg taacccatgc tgttattata gttgctgcaa aatgttcttc ctgatattga     3720

ttttatttgt taactgaagg tctccatatg tttgtttata ttgctaattt atgagaaaat     3780

gtaataattg caatgaatgt gaattataca gacaggcaaa cattttgtaa tcataattca     3840

catatacaca aaagcctggc tgaaatcttt agactatttg taccctctct acccacactg     3900

tttgtgattt atcatctgtc tctttagtgt cagttaaatt atgaactaac ttgaaaataa     3960

aagttgtttg actgaaagtg attgttgaat gaacaacaaa gttgaaagcc atggcttgat     4020

cttgtaaata tataaatgta aatgatatta aatctgtgat tccttttccc tccaaaggct     4080

tttgtgtaca tggcgctgca tttggctatt ttctttggaa ataaataatg tgatgtttct     4140

cttcctcttt tg                                                         4152


<210>  1172
<211>  4548
<212>  DNA
<213>  homo sapiens

<400>  1172
cggaagtagc gtcggcgcgg gagctgagcg gagtggcctt gccaccggag gggaagggct       60

gctggcgtta ggcctggctg ggtcgtgcgg ctgagcgtga ggctagaaag aaaaagcgat      120

cctccaagag tgagaacggg agatctgccg aggataacaa cctcccttgt ggccgaaggg      180

cgggggatcc ccacacgagg gctccgcttc gagagacggc gacaaaggaa agttcgtagc      240

gcgttccgga ggcccggcca cctctgagaa gggagacgac gctgctgggt ccgctgagcg      300

gggcgacccg agcttatata gaattggtga taggatcaca acttctgagg tcccagcaag      360

agtcctaaca tctagcagct ctaccaccag gacaggcccc ctaaaactaa ttccaacaag      420

cacctctgaa gtcttctcat tcacaggtta aggctacctt tccagataat ccaacagcta      480

aatcaccagt ttccaagggc atttgcatca cctatggaaa gcatcggatc cttatacacc      540

agatgttctt gacagctcat cccgtcattc ccccctgcac aaaagttgct ataccagcgg      600

acaagcaaga caactactga gcttcttttg attgtcaagt agatataata tcactgccag      660

caaaacagca caaaaagtgt ctcttcacag tatcactacc agttgggact atgctaagta      720

aatcagcttg cctagatgag gaccccttct attcttgggt agccaggatt tgaaggagat      780

actctgacct gtgccagtgg taagtgacta atacttttac acactgaact ggtcctggaa      840

actgagatgt cttctttgta agtgaagaat atacaacata atcttgaaga acggcacagt      900

ggtatgggcc acaagcatac tttatgtgtg taacggactg aaagacaaat taatcttggt      960

gaaaggattt ttcatctctt atttctattt gccagtgtta gtcagtgttc tgctggctta     1020

gattattacc tttttctggt tccttactgt gttttattct gatgggtcct agaaatccct     1080

ctcctgacca cttgtcagaa tcagaaagtg aggaagaaga aaatattagt tacctaaatg     1140

agagttctgg ggaagagtgg gattcctctg aagaagagga ctctatggtg cccaacttat     1200

cgcctcttga gagtcttgcc tggcaggtta agtgcctttt aaaatattcc acaacttgga     1260

aacctttaaa tcctaattcc tggttgtatc atgctaaact gttggatcca agcacaccag     1320

tccatatact tcgagagata ggtctaagac tctcccattg ttcccattgt gtccccaaac     1380

tggaaccaat tcctgaatgg ccccctctgg cctcttgtgg agtcccacct tttcaaaagc     1440

ctcttacaag tcccagccgg ctctctagag atcatgccac tctaaatgga gcactgcaat     1500

ttgccaccaa acagctaagc cgaacattga gtagagccac tcccatacct gaatacctaa     1560

aacagatccc taattcatgt gtttctgggt gttgctgtgg ctggctgact aaaacagtta     1620

aggaaacaac tcgtactgaa cccatcaaca ctacttattc ttacactgac ttccaaaagg     1680

cagttaacaa actcctaact gcatcactgt aaagatctac catttgctct gatatctctg     1740

atgttgctaa ttgagaaagt ggtacaaagt tagtcattac acagcccact aatgccttct     1800

cagtcaaact ctcttatgcc ctggcaagcc aatgaggata ccctttgaca aaccctgtgg     1860

ataaaatgat aatatcaagg tcaggcatgg tggctcacac ctgtaatccc agcactttgg     1920

gaggctgagg cgggtggatc tgctgaagtc agaagtttga gaccagcctt gccaacacag     1980

tgaaaccctg tctctactaa aaataaaaaa attagccggg cgcagcagtg cacgcctgta     2040

atccctgcta ctcgggaggc tgaaacagga gaatcacttg aacccaggag acggaggttg     2100

cggtgagttg agattatgcc actgtactcc agcctgggtg acagagcgag actcagtctc     2160

aaaaaaaaaa aaggagaatt agttaagggg accatattac aaaagatagt tgaatattct     2220

tcacactcac ttctcaccct ccccacccca atttactctg cctttctgaa tggctttaat     2280

gagatacctg attattaatg aagaaaagta gaccaccacc ccttttgtta tccagacttt     2340

agaacagcca ttgttgaaag caagaagtta gctacccaca ataatacctt tctgagcata     2400

ctcttctcta acatacattt ctgtggaagt agttgaatta aattgagtaa ctacacaaag     2460

gaaaatggca gggctatgaa tttctttccc agcttttata tagatgtgcc tacatatgac     2520

actctttagg gttcctttta ttttttcttt tttttttttt ttgaggtagt tgaattaaac     2580

tgggtaacta cacaaaggaa aatggcaggg atatgaattt ctttcccagc ttttatatag     2640

atgtgcctgc atatgacact ctttagagtt cctttcactt tttctttttt ttggaagggg     2700

gcggggaggc aggaggagtg cagttttaag cctagcctat actactacaa acttattatg     2760

gtacttaaaa ttacagcatg aacgttctat atcggagtct cccaccaggc tgtctctgac     2820

taaatcagcc tataagatca tcccttggga ttaaacaaac acctgttctg tagggaatgt     2880

gtttcctgaa tcttggtact cagacttttg tcaagagtaa ataacatttc aaaagatgaa     2940

tggaaaaatg attaagagag catttctgct ttcagcatta actgctaatg gattaaaatt     3000

ttaatctgta tagcatttcc tggagtaaaa gctcaagtac tttccacatc cattgcaaac     3060

ttttcaggaa cccttctaat tttttttttt tttttttttt tgagacggag tcttgctctg     3120

tcgcccaggc tggagtgtag tggcatgatc tcagctcact gcaagctctg cctcccgggt     3180

tcgtgccatt ctcctgccct gcctcccgaa tagctgggac tacaggcgtc caccaccact     3240

cctggctatt tttttgtatt tttagtagag acagggtttc accgtgttag ccaggatggt     3300

cttgatctcc tgacctcgtg atccacctgc ctcggcctcc caaagtgctg ggattgaacc     3360

cttctaattt taaagaacct tgttattaga aaatctcagc ctaatacaat ctgaagttaa     3420

gagttttagc agcattgttt ttctaagtag atttagctat agattttctt ctggccaaac     3480

aaggaagagt atatgccctt gtaaatgagt cttgttttgt ttatttaaat agtcagtcaa     3540

aacgtagaaa tcagtatacg taaaataaaa tgcatgagac tattaaatct tttcatatac     3600

tctacaaata aaatgaaatc tgtgtgtggt cctggttgac tgggcatcta aagggaatca     3660

gaaaagagat tgtgaaaagt tatatatata tcctcttcct tattttagtt ttgctttttc     3720

ctattttcca taattaagtg ccgtttacaa agtggcatca aaaaattgaa gcaggccagg     3780

catggtggct catgcctgta atcccaacag tttgggaggc tgagggcagg tggatcactt     3840

gagatcagga gttcgtgacc agcctggcca acatggtgaa agcccatctc tactaaaaat     3900

ataaaaatta gccgggcgtg gtggcatgtg cctgtaatcg cagctacttg ggaggctaag     3960

acaggagaat tgcttgaacc tgggaggtgg aggttgcaat gagctgagat cgcgccactg     4020

cactccagcc tgggcaacag tgagacaccg tctcaaaaaa aaaaaaggtt aggaatcaca     4080

aattgtgtaa atatatagca actttaagaa gagagaagaa tgcttataac ctagtgaata     4140

tttctgctga gccttagttg tcttgtctaa aggaaaaaag agggaattgt agaataaaag     4200

tatttgttag tggaaattat tgacctgaaa ccatatcata ttgttagtgt aactgaatgt     4260

atcagaaatt gttcctatgt aggtattctg tgaaactggt ttctaaaatg ttacaggaaa     4320

ctgtttcctt tttttttgtt tgtttgttta agtggaggtg ggaggaggta gggaagaggt     4380

ctgaatatta aaatatgttt atgttcatgt gttcataata cgttcctttt tctctctgtg     4440

tgtgtataaa agtgccttgc tcatgaatgc atttttgcta ttcacttcga aaggaagcct     4500

ttccccagct tggcagctga ataaaccaat agctttgtac atgctgaa                  4548


<210>  1173
<211>  3018
<212>  DNA
<213>  homo sapiens

<400>  1173
ggggaggggt gtgacgtaca tccggcgagt agctggcggt cccgggtgct gctggttagt       60

gtgctctgag ggagggtccg agccagccgc tgttttgccg gaggagcccc tcaggccgta      120

gtaagcatta ataatgtctt tcatctttga gtggatctac aatggcttca gcagtgtgct      180

ccagttccta ggactgtaca agaaatctgg aaaacttgta ttcttaggtt tggataatgc      240

aggcaaaacc actcttcttc acatgctcaa agatgacaga ttgggccaac atgttccaac      300

actacatccg acatcagaag agctaacaat tgctggaatg acctttacaa cttttgatct      360

tggtgggcac gagcaagcac gtcgcgtttg gaaaaattat ctcccagcaa ttaatgggat      420

tgtctttctg gtggactgtg cagatcattc tcgcctcgtg gaatccaaag ttgagcttaa      480

tgctttaatg actgatgaaa caatatccaa tgtgccaatc cttatcttgg gtaacaaaat      540

tgacagaaca gatgcaatca gtgaagaaaa actccgtgag atatttgggc tttatggaca      600

gaccacagga aaggggaatg tgaccctgaa ggagctgaat gctcgcccca tggaagtgtt      660

catgtgcagt gtgctcaaga ggcaaggtta cggcgagggt ttccgctggc tctcccagta      720

tattgactga tgtttggacg gtgaaaataa aagagtttta cttctctgga ctgatcctat      780

tcacagcttc ctcatgaact tttctaatag aacaaggaaa gctctccaac catgtctggc      840

gttgagaagc caagagtctc tgtcaactct ctcattgccc agtggtgaca tgtgctcttc      900

tccacactgt tgggaggtaa tgctgcccca cgtgctggtg caggtcagta tcctgggact      960

tggaagctgg caggatttgc cgggtaaagc tgtatgccat catggggcac ctgaaaagaa     1020

aaacacgtct caccactgtg gttgattcaa aagaaagtga ttctattttt taaagaaagc     1080

gttgttaatg taattggtat ccctcctaac tttttgagtt cacaatttac ttggtccaga     1140

gttttctatt cttttttttt tttaaactaa tgaatgacat ttagatactt cataaaatta     1200

tgaacagata tggaggccag agctcatttg ggtaaactta ctcctgctga gttagcaggt     1260

tggtgagaga agctcccctg agctcacctg tctctctgac tgccttggag taggtggcat     1320

aaccttgtgc acagagaact agaaaagggg cagaaccccg gccttgcagt tgtggcaggt     1380

ttccactgtg gtaagctagg ttcattcctc atcaaggaat gtgtagcaga ttgttcactg     1440

tggaggagtt aattatagaa tgggttattg ttgttattct tactcatgaa gttacagatt     1500

ttagccagtc tttgctttta tacttttgtg aaatttaatt tctctctata gcaccttcct     1560

ttttcgtttt cagttatcaa aagtgacttt gacctcataa aagagttgag aacatctctc     1620

gtgtcacata ctgcaggtgc atcagttact tttgcacaga ttctaggggg acatttttct     1680

gaataggaag acaggacaaa gttaacagct taagggctct taattctgtg agttgaggac     1740

ttaaaagtat tgtagcattt gtttggatcc atgaaaaatg tattcagtgg gctttaaaat     1800

ttccatttgc agaatttggt ctctcaggct gtttgggagc tctttttttt acattttttc     1860

tcctttgaca cctattttat tggtgtttaa agtaaaggtt aacatctgta gcttttccag     1920

gttttttttt tttttttttt ttttttggta tgaaattgtc tttctccatt gcagaaataa     1980

gctagggaaa cactaaccca aaaactttct gtagagctgt tcctttggag gcagcatcac     2040

ttattggcag taaagactca gtataaaagc accggcatcc ctacttgggt gatggggatt     2100

aattttatag cattccattt tcctagtgcc acatgtgaaa ttggattttg atgatcttaa     2160

tctatattct acccttataa taaaagatca aaagatatat ctcctatgaa cagattggag     2220

ataggagatg aaaagttggg aggatgtctt tattctaatg tgagggtagg gaaaatgtgg     2280

ataacattac tggggtgagg gaggcattgt tctttagttg gagttctcat tcttattctc     2340

cagtactgac ttgtggggaa agcatacttt ttcactgcca ggtactgaat gcagaggctc     2400

agtgaagtat atatgtggga agtgcatgca tttcgtttat tagcaaacat agctggatta     2460

agacaaagtt gttggtttgg aaaggggtta aagccttaag tgaacaaatc tagctaacag     2520

tgaatgaact aggtaatata acttgcatat ttttaatttc ctttggttaa aggtccccca     2580

tacttctctg ttcggagaca tgagaagtat gattacttca gtgttagttt tcttaatttt     2640

ttttttcccc tatttgtccc ttgtcacttt gttgcaagct agaaatctgt gggttataca     2700

tagggcagct ctttgtgaaa gtggtttatt ccactggaga aaggggattg aaaatcagtt     2760

agaaccaatg tatttcttgc cccacggaac actattccta taagatagct gaaagaagct     2820

gctgtgagga gctcagctcc aaacacagga tcagcacctt gtataggaat tcccatgaat     2880

tatgacttct cattctgttt tatcagagtg catatatgtc ctacttcagg aaaagtaaaa     2940

cagtcattta cgaaagaaag tcaatctgta tcctaagcat tttaataaaa agttaaaaca     3000

aaaaaaaaaa aaaaaaaa                                                   3018


<210>  1174
<211>  3536
<212>  DNA
<213>  homo sapiens

<400>  1174
agcgccggcg aggcgcggga ggaggagaag cagtggggag gcgcagccgc tcacctgcgg       60

ggcagggcgc ggaggaggga cccgggctgc gcgctctcgg gccgaggaac caggacgcgc      120

ccggagcctc gcacgcggcc aagctcgggg cgtcccctcc cctcggccgg gcgaactcaa      180

ggggcgcagc tctttgcttt gacagagctg gccggcggag gcgtgcagag cggcgagccg      240

gcgagccagg ctgagaaact cgagccggga acaaagaggg gtcggactga gtgtgtgtgt      300

cggctcgagc tccgggcaga ggcatttggg cccgaggccc ccgctgtgac tccccgagac      360

tccgcagtgc cctccactgc ggagtccccg cgcttgccgg caaaaacttt attcttggca      420

aacttctctt tctcttcccc tcctcctcgg cccccatctt ctgctcctcc tccttctcta      480

gcagattaaa tgagcctcga gaagaaaaac cgaagcgaaa gggaagaaaa taagaagatc      540

taaaacggac atctccagcg tgggtggctc ctttttcttt ttcttttttt cccacccttc      600

aggaagtgga cgtttcgtta tcttctgatc cttgcacctt cttttggggc aaacggggcc      660

cttctgccca gatcccctct cttttctcgg aaaacaaact actaagtcgg catccggggt      720

aactacagtg gagagggttt ccgcggagac gcgccgccgg accctcctct gcactttggg      780

gaggcgtgct ccctccagaa ccggcgttct ccgcgcgcaa atcccggcga cgcggggtcg      840

cggggtggcc gccggggcag cctcgtctag cgcgcgccgc gcagacgccc ccggagtcgc      900

cagctaccgc agccctcgcc gcccagtgcc cttcggcctc gggggcgggc gcctgcgtcg      960

gtctccgcga agcgggaaag cgcggcggcc gccgggattc gggcgccgcg gcagctgctc     1020

cggctgccgg ccggcggccc cgcgctcgcc cgccccgctt ccgcccgctg tcctgctgca     1080

cgaacccttc caactctcct ttcctccccc acccttgagt tacccctctg tctttcctgc     1140

tgttgcgcgg gtgctcccac agcggagcgg agattacaga gccgccggga tgccccaact     1200

ctccggagga ggtggcggcg gcggggggga cccggaactc tgcgccacgg acgagatgat     1260

ccccttcaag gacgagggcg atcctcagaa ggaaaagatc ttcgccgaga tcagtcatcc     1320

cgaagaggaa ggcgatttag ctgacatcaa gtcttccttg gtgaacgagt ctgaaatcat     1380

cccggccagc aacggacacg aggtggccag acaagcacaa acctctcagg agccctacca     1440

cgacaaggcc agagaacacc ccgatgacgg aaagcatcca gatggaggcc tctacaacaa     1500

gggaccctcc tactcgagtt attccgggta cataatgatg ccaaatatga ataacgaccc     1560

atacatgtca aatggatctc tttctccacc catcccgaga acatcaaata aagtgcccgt     1620

ggtgcagcca tcccatgcgg tccatcctct cacccccctc atcacttaca gtgacgagca     1680

cttttctcca ggatcacacc cgtcacacat cccatcagat gtcaactcca aacaaggcat     1740

gtccagacat cctccagctc ctgatatccc tactttttat cccttgtctc cgggtggtgt     1800

tggacagatc accccacctc ttggctggtt ttcccatcat atgattcccg gtcctcctgg     1860

tccccacaca actggcatcc ctcatccagc tattgtaaca cctcaggtca aacaggaaca     1920

tccccacact gacagtgacc taatgcacgt gaagcctcag catgaacaga gaaaggagca     1980

ggagccaaaa agacctcaca ttaagaagcc tctgaatgct tttatgttat acatgaaaga     2040

aatgagagcg aatgtcgttg ctgagtgtac tctaaaagaa agtgcagcta tcaaccagat     2100

tcttggcaga aggtggcatg ccctctcccg tgaagagcag gctaaatatt atgaattagc     2160

acggaaagaa agacagctac atatgcagct ttatccaggc tggtctgcaa gagacaatta     2220

tggtaagaaa aagaagagga agagagagaa actacaggaa tctgcatcag gtacaggtcc     2280

aagaatgaca gctgcctaca tctgaaacat ggtggaaaac gaagctcatt cccaacgtgc     2340

aaagccaagg cagcgacccc aggacctctt ctggagatgg aagcttgttg aaaacccaga     2400

ctgtctccac ggcctgccca gtcgacccca aaggaacact gacatcaatt ttaccctgag     2460

gtcactgcta gagacgctga tccataaaga caatcactgc caacccctct ttcgtctact     2520

gcaagagcca agttccaaaa taaagcataa aaaggttttt taaaaggaaa tgtaaaagca     2580

catgagaatg ctagcaggct gtggggcagc tgagcagctt ttctcccctc atatctgcgt     2640

gcacttccca gagcatcttg catccaaacc tgtaaccttt cggcaaggac ggtaacttgg     2700

ctgcatttgc ctgtcatgcg caactggagc cagcaaccag cacatccatc agcaccccag     2760

tggaggagtt catggaagag ttccctcttt gtttctgctt catttttctt tcttttcttt     2820

tctcctaaag cttttattta acagtgcaaa aggatcgttt ttttttgctt ttttaaactt     2880

gaattttttt aatttacact ttttagtttt aattttcttg tatattttgc tagctatgag     2940

cttttaaata aaattgaaag ttctggaaaa gtttgaaata atgacataaa aagaagcctt     3000

ctttttctga gacagcttgt ctggtaagtg gcttctctgt gaattgcctg taacacatag     3060

tggcttctcc gcccttgtaa ggtgttcagt agagctaaat aaatgtaata gccaaaccca     3120

ctctgttggt agcaattggc agccctattt cagtttattt tttcttctgt tttcttcttt     3180

tcttttttta aacagtaaac cttaacagat gcgttcagca gactggtttg cagtgaattt     3240

tcatttcttt ccttatcacc cccttgttgt aaaaagccca gcacttgaat tgttattact     3300

ttaaatgttc tgtatttgta tctgttttta ttagccaatt agtgggattt tatgccagtt     3360

gttaaaatga gcattgatgt acccattttt taaaaaagca aggcacagcc tttgcccaaa     3420

actgtcatcc taacgtttgt cattccagtt tgagttaatg tgctgagcat ttttttaaaa     3480

gaagctttgt aataaaacat ttttaaaaat tgtcatttaa aaaaaaaaaa aaaaaa         3536


<210>  1175
<211>  4717
<212>  DNA
<213>  homo sapiens

<400>  1175
tccggaggcg agccgagcgc ggtggtgagg ccgcctcagc gaaaaaaatg tccgcctgaa       60

gagacccaca agttctattc ggggggaccg acagcccgcc ccgggaggaa ggggcggcca      120

ggcccgaaag ccgcctcccc ctcccagacc cgagagctcg tgcggggcaa agtgaaccga      180

gccgctgggc ggtgcaaggg gaagcccaag cccgttctcc cggccaaagt gaactttaat      240

cggggtggtt ggatgcggag acggggcggc agaagtggcc gaagatgaat ccccagcaac      300

aacgcatggc cgctataggg accgacaagg agctgagcga cctactggac ttcagtgcga      360

tgttttcccc acctgttaat agtgggaaaa ctagaccaac tacactggga agcagtcaat      420

tcagtggatc aggtattgat gaaagaggag gtacaacatc ttggggaaca agtggtcaac      480

caagtccttc ctatgattca tctagaggtt ttacagacag ccctcattac agtgatcact      540

tgaatgacag tcgattagga gcccatgaag gcttgtcccc aacacctttc atgaactcaa      600

atctgatggg aaaaacatca gagagaggct cattttccct gtacagcaga gatactggat      660

taccaggctg tcaatctagt ctcctgagac aagatctggg gcttgggagc ccagcacagc      720

tatcttcttc aggaaaacct gggacagcat actattcatt ctctgctaca agttccagga      780

ggagaccact ccatgactct gcagcgcttg atcccttgca agcaaaaaaa gtcagaaagg      840

tgcctcctgg tttgccttct tctgtatatg caccatcccc aaattcagat gatttcaacc      900

gtgaatctcc tagttatcca tctcctaagc caccaaccag tatgttcgct agcactttct      960

ttatgcaaga tgggacccac aattcttctg acctttggag ttcatcaaat gggatgagcc     1020

agcctggttt tggtggaatt ctggggacct ccacttccca catgtctcaa tccagtagtt     1080

atggcaacct tcattcacat gaccgcttga gttatcctcc acactcagtt tcaccaacag     1140

acataaacac gagtcttcca ccaatgtcca gctttcatcg cggcagtacc agcagttcac     1200

cttacgttgc tgcctcacac actcctccca tcaatggatc agacagcatt ctaggaacca     1260

gagggaatgc tgctggaagc tcacagacag gtgatgcact tggaaaggct ttggcatcta     1320

tttattctcc tgaccatacc agcagtagtt ttccgtcaaa tccatcaaca ccagttggat     1380

caccttcacc tctcacaggt accagtcagt ggccaagacc tggagggcaa gcaccttcat     1440

ccccaagcta tgaaaactca ctccactccc tgcagtctcg aatggaggat cgtttagaca     1500

gactggatga tgcaatccat gtgctgcgga accatgctgt gggaccttcc accagtttgc     1560

ctgctggtca cagtgatata catagtttat tgggaccatc ccataatgca ccaattggaa     1620

gcctcaattc aaactatgga ggatcaagcc ttgttgcaag cagtcgatca gcttcaatgg     1680

ttggaactca tcgggaagac tctgtcagtc tcaatggcaa tcattcagtc ctgtctagta     1740

cagtcactac ttcaagcaca gacctgaacc ataaaacaca agaaaattat agaggtggct     1800

tgcaaagtca gtctggaact gttgttacaa cagaaatcaa gactgaaaac aaagaaaagg     1860

atgaaaacct tcatgaacct ccttcatcag atgacatgaa gtcagatgat gaatcctccc     1920

aaaaagatat caaggtttca tctagaggca gaacaagcag tactaatgaa gatgaggatt     1980

tgaaccctga acagaagata gaaagggaga aggagaggcg gatggctaac aatgccagag     2040

aacgcttacg cgtgcgggat attaatgaag cattcaaaga gcttggccga atgtgtcagc     2100

ttcacttgaa gagtgaaaaa ccccaaacaa aactccttat tcttcatcaa gccgtggcag     2160

tcatccttag tctagaacag caagtcagag agaggaacct taaccccaaa gcagcctgcc     2220

ttaagagaag ggaagaagaa aaagtttctg ccgtatcggc agagccgcca accacactgc     2280

caggaaccca tcctgggctt agtgaaacta ccaaccctat gggtcatatg taaacatcag     2340

ccagttccag agttatcagt aggctagata gaaggtgacc tctcctcata aggacttgga     2400

caactcagat tatctgaaga cacaaacctg acaggaggga gaagaaaaaa caaaacactt     2460

gaaccaagaa actcaaatgt aatcctacga tcaaagcaac tggtcaacac ttccatcaga     2520

agtgaagata ggaagctcat cagatagaac atcagcccat gagatgtttg caacaaatct     2580

tttgttgcaa gcagtgtgtc gcttctgcac aatcagagac tgtctcgatc tctccactca     2640

ccgtggaagt tgccttgtgc ctaaactgaa ttgacaaatg cattgtaact acaaatttta     2700

tttattgtta tgaaactgta aggtctacat ataaagggaa aaagttaatg tggaaagctg     2760

atctacactc agctgatgcc agcatacatt aaagcggttc acgtgcagag aacaaagcag     2820

tgacaaccat tggcccttag cattcccggc atacctatta gtgtcttaaa aaggaaggga     2880

aaagtctttt gttgccctct cctatcctct tgccatatga atagcgtttt ccatgaaata     2940

ggaaaatatt acttggtata gcatttctct tgctctcatt ttttgattta tttttatttt     3000

ctctttgtgg gtgttatatt tgatctctaa atctgaacag tttatggtca cagtccagcc     3060

tcctccgtgc agccctgtgt gctttgcaca tttaccttac agtggtaagc agagaccatc     3120

tgtgaccata gcctagctag cattttaaaa ggggaaattt tgttctctag gttttccccc     3180

aaataaacat tgctttattt ctaataataa ccaagacttt tcaagcttct agatctcata     3240

ggaaagcttg taatagcaaa attgtaaatt acaagggaag aatctacttt ttagaaatcg     3300

ctttgttttc caagcagtaa gtactacata cagtacttgt aaagtgttag ctgtaagtaa     3360

gcacaaaata catttaaaat acaaagacga ttttttcagg ctgtgattat ggtgaacata     3420

acaaaaccca gtagtcacca aggcaggtag tgtgataaat gaacacacca ctctgaggct     3480

aattacctaa tggaatacaa gagcaatggt cacccgtatt tccttatcct agcctttatt     3540

tctctgtcat ttggatggct ggtcaatggg gaagaattga gtgggtgatt taatcaactg     3600

caaaccatct gcccctgtcc caaaatgatg agccagatta gcattaaacc agtacttgtc     3660

agtccatctt aatactgttc attaaggcac tctctgtctc taatccttag gagttgtttt     3720

aaaagacata atcactttga acttccatga aacctgtctt ccaccacaac aaccctggga     3780

gagaaaaaca tgctaaagga ggtatcttgg cttaataatt ccttatagcc aatatcaaca     3840

gtggcaatca gcacacagag gaaaggaccc aaatcactat gtagcttaaa gatttctgtt     3900

aatttgaaag aacaaaaaca agacagaact tctggtactc taatcaggat gattcctaac     3960

aagtcagtca tttgtgaact tagtggactt tttggttact ttaatttgca tatattctcc     4020

agttacatcg gactctatct gtggccttgt tcttcatttc agtgttaatc agctaaacag     4080

aagttgttgc ttatgatgtg tgagtgaaca tatgccactg cctggccttt ttttcttcag     4140

agcttgttgt ctttttcgct atattagact ttgcagtatg cccagaagct ttccttcata     4200

aaatagaaag aaaaaaacat ttggcttatt tttcactgta gctagtcttt tatacaataa     4260

tcttgtaaga aaatttcttg aattctaaat attactcttt ctagattttt gaaatcaaaa     4320

agttttcagt aaaaagtttc ttactttatt ttattatatt aggtagtaaa aaatgtaggg     4380

ttatttacca taacctgttc attaatatca gaaatttaca atagcatttt aagaccatag     4440

taggattcta gcataccgtg tagtacctat ggagtattgt aagagctaat tgttggagat     4500

gaattgcttc tcatcttgtt ctccagtttc cattgttggt ttattgcaga tttgtatcct     4560

gtgtcaaatt caaggtatta ttgataaacc ttttcaacca gcagcaagaa gttcaaattt     4620

ttttctgtca ctgtaacaga aaacacaata tgtatataac atttatgtag caataaatgt     4680

gccatctttt ttttaacaca gtaaaaaaaa aaaaaaa                              4717


<210>  1176
<211>  4369
<212>  DNA
<213>  homo sapiens

<400>  1176
ggctcaaata tagttcaaga caacagagac aaagctaaga tgaggaagtt ctgtacagtt       60

taggaaatag aggctttcaa agataattcg cagtgatgtg aaactggcct cccaagccct      120

gataacaaca tggccaacgc cctggccagc gccacttgcg agcgctgcaa gggcggcttt      180

gcgcccgctg agaagatcgt gaacagtaat ggggagctgt accatgagca gtgtttcgtg      240

tgcgctcagt gcttccagca gttcccagaa ggactcttct atgagtttga aggaagaaag      300

tactgtgaac atgactttca gatgctcttt gccccttgct gtcatcagtg tggtgaattc      360

atcattggcc gagttatcaa agccatgaat aacagctggc atccggagtg cttccgctgt      420

gacctctgcc aggaagttct ggcagatatc gggtttgtca agaatgctgg gagacacctg      480

tgtcgcccct gtcataatcg tgagaaagcc agaggccttg ggaaatacat ctgccagaaa      540

tgccatgcta tcatcgatga gcagcctctg atattcaaga acgaccccta ccatccagac      600

catttcaact gcgccaactg cgggaaggag ctgactgccg atgcacggga gctgaaaggg      660

gagctatact gcctcccatg ccatgataaa atgggggtcc ccatctgtgg tgcttgccga      720

cggcccatcg aagggcgcgt ggtgaacgct atgggcaagc agtggcatgt ggagcatttt      780

gtttgtgcca agtgtgagaa accctttctt ggacatcgcc attatgagag gaaaggcctg      840

gcatattgtg aaactcacta taaccagcta tttggtgatg tttgcttcca ctgcaatcgt      900

gttatagaag gtgatgtggt ctctgctctt aataaggcct ggtgcgtgaa ctgctttgcc      960

tgttctacct gcaacactaa attaacactc aagaataagt ttgtggagtt tgacatgaag     1020

ccagtctgta agaagtgcta tgagaaattt ccattggagc tgaagaaaag acttaagaaa     1080

ctagctgaga ccttaggaag gaaataagtt cctttatttt ttcttttcta tgcaagataa     1140

gagattacca acattacttg tcttgatcta cccatattta aagctatatc tcaaagcagt     1200

tgagagaaga ggacctatat gaatggtttt atgtcatttt tttaattaaa aaagaaaaat     1260

tcatataatc gtgtttaaaa cacaaatgaa gtcagtattt gcctttgtta acccttatcc     1320

atttgttgac atgtagactg tttacaaaaa aaaaacacat ggttaaatgt taaattttaa     1380

ttaaggcccc caaaaattaa atataacttt ttaaaatgaa aggagtcacc ttttacatga     1440

ctcaggtgaa aaaacagtat aaacattaat ttactttgtg ttcaaaagaa aattccaact     1500

gctgttgggg aaggacacag aaaagaaaaa taaccaccca agaaaaacaa aaacaagaaa     1560

aacaaatctt atacaatctt agtatattta tcaaactagt agctagaaag tgaatatgca     1620

cattactaag acaaaaaaca agtgtaattc agaactactt gatttttttt agttaaatgc     1680

aataattatt atgcttagtt ttataacctg ctctccttgt gaattcttcc ttcaaatgat     1740

tacttaacgc agtagtaata gctagctgta ggatgtcctt taaatttttg tgcaaaaaaa     1800

aatttatacc aggtatttgg aaatatactt tacaatattg gaaaatgaag tatttttaat     1860

gtattacagc aattatgttt ctaagcttaa tgttaagcat gtagtcttag aataggacat     1920

gaaattaaat tgtatgtagc ttggaatata ttgcttcaga aaactgaatg tgtatgtcgg     1980

tcatattgcc tttataacca tgctaatatc tatgctttat acatactcaa acttgccttg     2040

ccttaaaaac atacatacta catacttaaa tcaggaattc tagccatctc acagaatacc     2100

aactaaaact aagtgcattg agatctgaga ttggtaaacc cagattcatt taccacagct     2160

gtaattaagt ttttagaaac tattctcttt ttggggaaat ccattgaagt taatttctgt     2220

tatcttatta gaagaaaatg atgttgatat gtgtttcaga ttttccattt gaaatcttat     2280

aattaatttg atttatttac tgtaagtagg aggtataaat gacactctta aattggaagg     2340

aggggtgttt tagtgtctgt tttaggtcaa aattagtgat tctattttta tcaaaagttt     2400

tatcctgaag tttcaggacc actcttcctt aataaacttg ttaatggaaa gcgagcttta     2460

tgaacattta aaaatgttgc tgctgctttg ttgcttaaaa agaaagttgc caagagagac     2520

ttcttaggga aaatatttgg gttttttttc caaaaattgc tgaaatattg ttttgccatt     2580

tttaaaaagt ctcaggttat taccactctg ccattaaata tttgtatgcc tgcattttta     2640

aaaattctgt gcatgtactt tatggagtac attctatttt tgttttcaga taccctacaa     2700

ccaatttttt ttagtaatct tttagaattg aaattatcat aaatgatcga gaataatcat     2760

cacatagttt aagattgtat atgttgagta gtttaaaaca atctttgcat tttacagtaa     2820

gaatcaaagt cccttcagtg tgcctttgtc agctaatatg tgaccagcaa tgacaacctt     2880

gggagtattt attaaatatt atgctatgaa tataggcaac acagaacagg gtttgcagta     2940

tagcgtcttg atgctaaatt ctcatatacc tctacacgag aaatatggag gagaaaaaca     3000

agcatttaca tatattcttc gtcactttga agatgcatgg cctgaactcg actgcttgtg     3060

tttgtttaca tatcaggcat acccaggcat ctcctgcagc cagaggttcc attgctgtct     3120

ttgctcagtc ctcttttaaa atatgaatta gtggacaggc acggtgcctc acacctgtaa     3180

tcccagcact ttgggaggtc gaggcaggtg gatcacgagg tcaggagatc aagaccatcc     3240

tggctaccac tgaaacccca tctctactac aaaaaaatta gccgggcgtg gtggcgggca     3300

cctgcagtcc cagctactcg ggaggctgag gcaggagaat ggtgggaacc cgggaggcag     3360

agcttgcagt gagccaagat cacgccactg cactccagcc tgggcaacag agcaagactc     3420

tgtctcaaaa aaaataaata aataaattat gaatgagtat tttctagaaa ttcaacttgc     3480

taagcctgta atacttaagg gtagtttatc tagatacagt actttcttcc ctgataagta     3540

gtatcattgg agcccttagg tataggagaa gaggaagaag tttaaaaagt gtaagtgggc     3600

cgggcgtggt ggctcatgcc tgtaatccca gcactttggg aggccgaggg gggcggatca     3660

cgaggtcagg agatccagac tatcctggct aacaaggtga aaccccgtct ctactaaaaa     3720

tacaaaaaaa aacattagcc aggcgtggtg gcgggcgctt gtagtcccag ctactcggga     3780

ggctgaggta ggagaatggc ttgaacccag gaggcggagc ttgcagtgag ccgagattgc     3840

accactgcac tccagcctgg gcgacagagc aagactccgt ctcaaaaaaa aaaaaaaagt     3900

gtaagtggat taaaagagaa acttggtcta gttcataata tttttaatag ggctttccct     3960

ggctgctgga aaacttaggc cagtaagcat ctctttgttt aaagtcctac aagacaattt     4020

gaaataattc attgttcatg ccaaaattct aagtactgtt tttcttagca agtgtaacat     4080

aatcaggaac aatgggtaca agtaaaacat tctttggatg atattcaaag ccttattagc     4140

actgcacctg aataataggt cattttgcct cactcatttg ccaaagtagc catttctaag     4200

ttaaggaagt ttttagatag gctcatagcc ttgtatttcg ttttagattg taagctcaat     4260

ggcagggata ctatattggt aattatgttt tcatatagca accaccacag tatattcttg     4320

gtgcttaata aatgtttata attgttaaca ataaaaaaaa aaaaaaaaa                 4369


<210>  1177
<211>  3927
<212>  DNA
<213>  homo sapiens

<400>  1177
attcccaact gccagtgatc tctgaagccg actctgaggc tccctctttg ctctaacaga       60

cagcagcgac tttaggctgg ataatagtca aattcttacc tcgctctttc actgctagta      120

agatcagatt gcgtttcttt cagttactct tcaatcgcca gtttcttgat ctgcttctaa      180

aagaagaagt agagaagata aatcctgtct tcaatacctg gaaggaaaaa caaaataacc      240

tcaactccgt tttgaaaaaa acattccaag aactttcatc agagatttta cttagatgat      300

ttacacaatg aagaaagtac atgcactttg ggcttctgta tgcctgctgc ttaatcttgc      360

ccctgcccct cttaatgctg attctgagga agatgaagaa cacacaatta tcacagatac      420

ggagttgcca ccactgaaac ttatgcattc attttgtgca ttcaaggcgg atgatggccc      480

atgtaaagca atcatgaaaa gatttttctt caatattttc actcgacagt gcgaagaatt      540

tatatatggg ggatgtgaag gaaatcagaa tcgatttgaa agtctggaag agtgcaaaaa      600

aatgtgtaca agagataatg caaacaggat tataaagaca acattgcaac aagaaaagcc      660

agatttctgc tttttggaag aagatcctgg aatatgtcga ggttatatta ccaggtattt      720

ttataacaat cagacaaaac agtgtgaacg tttcaagtat ggtggatgcc tgggcaatat      780

gaacaatttt gagacactgg aagaatgcaa gaacatttgt gaagatggtc cgaatggttt      840

ccaggtggat aattatggaa cccagctcaa tgctgtgaat aactccctga ctccgcaatc      900

aaccaaggtt cccagccttt ttgaatttca cggtccctca tggtgtctca ctccagcaga      960

cagaggattg tgtcgtgcca atgagaacag attctactac aattcagtca ttgggaaatg     1020

ccgcccattt aagtacagtg gatgtggggg aaatgaaaac aattttactt ccaaacaaga     1080

atgtctgagg gcatgtaaaa aaggtttcat ccaaagaata tcaaaaggag gcctaattaa     1140

aaccaaaaga aaaagaaaga agcagagagt gaaaatagca tatgaagaaa tttttgttaa     1200

aaatatgtga atttgttata gcaatgtaac attaattcta ctaaatattt tatatgaaat     1260

gtttcactat gattttctat ttttcttcta aaatgctttt aattaatatg ttcattaaat     1320

tttctatgct tattgtactt gttatcaaca cgtttgtatc agagttgctt ttctaatctt     1380

gttaaattgc ttattctagg tctgtaattt attaactggc tactgggaaa ttacttattt     1440

tctggatcta tctgtatttt catttaacta caaattatca tactaccggc tacatcaaat     1500

cagtcctttg attccatttg gtgaccatct gtttgagaat atgatcatgt aaatgattat     1560

ctcctttata gcctgtaacc agattaagga atacagctct taaaaaatca agaacttcct     1620

gagtttcaca tataaaatgg tgacaaacac ctgcttctga taaagtttat ccaattttgt     1680

atttatagta ttctattgta ataatagaat tctattatgt gcttccctcc ttagacatag     1740

tttttctcct tttgtactaa ccagtacttc catctatatt gagctaaact gtctttgaac     1800

agtcaactct gcatcatgtg cctgcctgat ttggattggt ttcacttttt tttttgtttg     1860

accatagccc attctatcag tcaagatgac tgaataattg tgtgttaaat acaactcatg     1920

ataaggagaa cctttatgga aacaagaagt tttatggcaa tcgagaggga attatttata     1980

tgtacttctt aatactatgc ttcccaatat tttttcttac taaaaataac aaaaatattt     2040

aaaccttctg aaatctattc agttatcatt aggatttgca cacaatgcaa ctaataattc     2100

atgctttaaa aagtaggtta tttctgttga agagaaaatt atcagcaggg aagagtctac     2160

tagaaaattc atgtgctagt cattcttggg gatttaatat tttgctggag ttaattcact     2220

atatccagac ctgtatcttt catttattgc tgagccatgt gcagtctggc atctcaacaa     2280

cctcaacaac ctcaacaacc tccaagacat gtcagtttct gtagtgttca cctcaaatct     2340

gacactggaa ttggaactga tttagaaaca accatttcat tcatttggta tgactagctt     2400

catgactagc ttcatgaata gcttcatgaa tagcttcatg acttctcgct aacaatgata     2460

gtataattct gcctgttctt caggattgaa attttgaact caatttagat ttcctgtttt     2520

ccctcatata ccacatctaa acagtctcca aatctttatg cttttttttt tttttttcga     2580

aaaagttcac ccaatcccta ggctttttac ttttttcttt ttcttttctt ttttcttgtt     2640

tttttttttt tttcattttg ttttgttttg ttatgttttt ttagacaggg tcccactctg     2700

tcacccaggc tggagtgcag tggtgcaatc acaggacact gaaacctccc acctagctgg     2760

gactagaggt gcaggccacc acaccagcta atttatgtaa tttttgtaga gacgagtttc     2820

accacgttac ctaggcttgt cttgaacacc tgggctcaag caatcttcca gccccagcct     2880

cccaaagtgc tgggattaca ggtataaacc acaatgcccc cgtttttact ctttactgca     2940

tccttcccat cagtattaat tcctcagaaa tttagtacat tcctccacca tttcaaaatg     3000

ctcccagaac tcacactagt tggtacttaa ctacaacctt caacctcacc atttaatttt     3060

gatgtatgtt tttggattta ccaacagtac tttctttcat gactactttg atttagttaa     3120

gaatgctcac tgtacactga atgttaatta ctcagctaat tcacactgat ttcctgttta     3180

aaaatatgat cccctccagg ccattcatgt gaagtcaggg tacagctgat gccagctaca     3240

gaatcactat gtttcaatat ggaatatgaa aagtcctaac acataattgc aaatcatttt     3300

ctactatggt atacaaattt tatcattaca aaatagtatc agcttttttc acttaaggaa     3360

aataatacat cttcattcaa atattcagtg cataaataat tgccttaaat tgagtctttg     3420

ctgtggaatt tgagagtttt ggaaatcaaa ggcccttgtg aaacatttcc tgttgccatt     3480

tatttataga tagcaatagc ttcaaatgag tgggaaagtc tacttaggtg aagtggtaaa     3540

tagtcactaa gattgtataa atagcgcatt gatgagttgc ctaattgttt tctccaacaa     3600

taaccactgg tccattggtt cactacttac tcaagaaaga catatactga gatggcttga     3660

aatgtttaat gcatgtgaac gttattttta ccgtgttttg gaaaaagatc ttgatgttat     3720

tgtcttcctt tattttccac aattaagtgc atctaactgt gaattgtata tggaattaca     3780

ttattcagca tatacatata tttacctgct ttgttcattc tctgtattca aaattaacag     3840

atcatgctga aaaccactca aacgattata ttttttacat tataagaagt aaaatatatt     3900

attctgaata atgaaaaaaa aaaaaaa                                         3927


<210>  1178
<211>  5121
<212>  DNA
<213>  homo sapiens

<400>  1178
agaggatcgg ccgggcgcgg cgggaaggag gctgcgggca gcgaggagcg gctggcgctc       60

gaggcggcgg acggcaccat gtccccgggg agcggggtga agagcgagta catgaagcgc      120

taccaggagc cgcgctggga ggagtacggg ccgtgctacc gcgagctgct gcactaccgc      180

ctaggccgcc ggctgctgga gcaggcgcac gcgccctggc tctgggacga ctggggcccg      240

gccggctcct cggaggactc ggcgtcgtca gagtcgtcgg gcgccggggg ccccgcaccc      300

cggtgcgccc cgccctcgcc cccgccgccc gtagagccgg cgacccagga ggaggcggaa      360

cggcgggcgc gcggggcccc ggaggagcag gacgcggagg ccggggacgc ggaggccgag      420

gacgcggagg acgcggctct gccagcactg ccagtgaaag atgtagaaga taaacctgaa      480

caacaaacca gaacaagaga gactgacaaa tcacccacca gtactgagcc tcgacagcaa      540

ccaagtgcct tatttgctag aggaaacagg aaagcggtca aaagtcccca aagatcatcg      600

agtaaaataa aagaaaacaa gcatccattt gctctttatg gctggggaga aaaacagacc      660

gatacaggaa gccagaagac tcacaacgtc tgtgcgtccg ctcctgtgca cgagattcat      720

gaatcagcat tacgagccaa gaacagaaga caggtggaaa aaaggaaact ggttgctcaa      780

aggcagcgag ctcactctgt ggatgtggag aagaacagaa agatgaaggc ttcctcctca      840

gagaacccgt ggatgacaga atacatgagg tgctattcgg caagagctta aagaaacact      900

tgcgtggaca gcctctttta aaaagtgtaa atgactgaaa ggaaaaacaa aacaaaaacc      960

atcaaaagaa acggacacag gtttaagaaa ccaactgatt atgcaaggtt ttttttaggg     1020

aatttgtaaa agattgtttt attttgatga atattggtca cctacctcgg cagtagggca     1080

gacagttgaa gccatagaca tttggttatt tatgaagata attccctaaa tctttgatat     1140

tcttataagg tttttgtttt aaagcatctt aatcttttaa gatactgaca ccaaatgcct     1200

ttaaatggca acagatgctt acagttcagt attcttttca taagcttagg tagagcctat     1260

tatcatcttg ttctaaataa ctttccagat tccatagcta taagatcatt ccatcctaca     1320

gcataagact cgttttcctt atatgccgtt ttgtttgtga aagaatatca agtcaaaaat     1380

gagtgtcagc actactactg attccatgta taatgaaagt agaactttgc tagttcctga     1440

aaatttttaa cttatttgta tttcagttca gcagcatctt tatgtagatt gtgatattta     1500

agaattatct gggctgggcg agggtctctt tttctctttc agtgatcatc taggcagtta     1560

ttatttaata gtttaatagc tcaagtacat tccaatagac gaagtgcaca caacacaata     1620

tgtgtgtaca gtagtagtaa agtttctttt gagtagtcaa agactcactt tttttattgc     1680

cttttttttt ttttttaaag aatacatact gtggattcag tcccttgtca cacttgacct     1740

tttggcatac acccactgtg gacttttgcc tcttctgtaa tggctggcaa tgacatttca     1800

aacttacaat ctggaattgc acttggtaca ttggcattgc ttgttccact gggatgggga     1860

ccagtgtgaa gatgcctgtt agatagactg cccaccccta ctttctcttt ttctttatag     1920

cacttaacaa taacaaagtc ttgatgatgt acagtattca aactttaggt tgaaatacgt     1980

tactctttga ttcctagcca gtagatctta tctacacttt aatgggagag aatggtggtg     2040

tgtgggtagg cacaaattta tgtaaatagt gctccttctc tttagtatgt ttgctttggg     2100

ggtagaaaaa tggttttaac aaacactggt ttccatcaaa tgaatgatgt cttctccatc     2160

ctgtggagac aagaatctgc tagaaggata tgtgctaagt tccttataag agataatggt     2220

gctctgccta tgccagcttg gcacccgaag atgtgtgagt ggacgtgagg ctgagtatta     2280

ccttagtatt tttctctggg tctttggaaa accatagtca atttttagaa catattgctt     2340

tcattcccca taaactcttc acacatgata actgtttaag ctttgaaaac acatactgaa     2400

gtattgtgag cttaaaaaaa ctttttaaat atttgcatag ttttgaggtg aatttgtttc     2460

cttacagatc tctcctaatc attgagatgt atatttcaaa agaggaaatt ttacatgttg     2520

tccaaaacag ccttgctagt aactggtgaa ttttggtatt aactattatt aaagtcttta     2580

aacgacacag gtacctaaag atcaccttaa tgtggcaatt tgtgatggtg tagctagctg     2640

attgtgaaaa ctgttccttt aaagtcgctt cttgcatgtt cggtgttagt catccagctc     2700

aggcttgtgt tgcagctgac aatctaggaa agacggcctt agagagtggt gcaggcccca     2760

cactgacgga ctgccttaga aacccgactt cctctagact ttgaaccgcc agacttttct     2820

cttgtttaga aaacaaactt atatttaatg tacttactac ttaaaactcc agacagagat     2880

ataatgtaga aggcaaatat tggccaattt tttcctcttt ttaagtggaa gacaaatgaa     2940

cgggattttt aaagtgcttt taaagtgcat gaatggttaa taaatcagta tgaattgtaa     3000

gccttcatct tacatccaag tccttagttg gttagggttt cttttctttc ttttttaaag     3060

agtgtcaatt accttttgaa cctgtgaaaa tttgatagtt gttaacagtc tgatggtcct     3120

aattctttct tttcattcta gaaatgaatg tggttgtaat catgttccta attcttggga     3180

caacctgcaa gacagtgaga cagtttaaaa attacctttc atgttgaaaa agtctgaaac     3240

agagaaccca atgatattta aaataaatgc tacataaaac tctttttaaa attttgattt     3300

taacttaatt aaaacaatgt cataaatatg ctttttgatt ttgttactgc ttttaatatt     3360

aaagtaatag aatattgaag caatattgtc tagcactctg ctggacatta agtccgcggg     3420

aggagaagtg aacaggaatc gattctttgt cttttaactg cccttagtta ggagatgtta     3480

aaatacttgg cacctctggt tatatgtatg ttatgtgtgt tctcccccct aaaatttcta     3540

agcacattta ttcactttta aaatgaatct ttaaaagatt atagttagta gttatagtta     3600

atattctatt tacttggaaa aatgtgaata aatggatctt caaaagattc attttaaaaa     3660

tgaataaatg tataataggc tataggtgat cttacttgcg tattaggtag gaggcacata     3720

tttataccat ttcatatgta atatctttgt cattgtgttt catcgaagat caattgctag     3780

caacttgaag ggtatttata cttgggtcac ttgaactcag ctgactaaat tgtaagaacg     3840

agagcaagca agatggctgt tattggaagc cataacttcc agaagataat tctgcacaat     3900

tcgtaagtta aaaaaaatct gtagggtctt ccactatcct ttttcaggtt gataatgctg     3960

ttctgggcac acactttgta aatggaatgt tatggtacag tcgcctctca gtatccatgg     4020

ggcattggtt ccaggcctcc cttaggatgc caaactccat ggatactcaa accccttcta     4080

taaaatggtg tagtatttgc atatatccta gacacatcct cctgtatgct ttaaatcatc     4140

tctagattac ttaaaatacc taatacaatg taaatgctct gtaaatagtt gttatactat     4200

attgtttagg gaataatgac aaggaaaaaa aagcctgtac atgttcagca caagtgaaac     4260

catccttttt gcccccaaat attttcaatt tgtatttggt tgaatccatg gatgcagaac     4320

tcacggatac agagggccga ctgtactttc tttaaagtgt tcaaaagtat tactagcaaa     4380

gaggaggagg agcaaagcat atatcagaag taaaacaatt tttcttgttg actgctttgg     4440

taaaaaacag tttgatggat agttttacat ttcactggac tagataaaaa atggtgctaa     4500

tatttatgta gcttgatgct atagttgctt tggtatcaaa cttaatacct aacccatata     4560

agatccttat tatataattt tgtgatcagt aaaatgatat tttaaagagt gatcttaaaa     4620

atatgacctg gtcattgcac aacgtttgca tttgaaatga atttttgtac tatagggtgg     4680

atatggagtt attcagtgca agtgtgtgct taatatcaaa ccctatgcaa ggagctatgt     4740

ctagattttt ggtccaaatt tgcctccttc aagcctacta gtgtgagatg gaaaaaaatc     4800

gattgctctt ttaatattat ttccattttg aaattctcga cacttgaatg aaggcagtag     4860

aggcctcttt ttggatttct cttctaataa caaaacttta tttagggaag gtttccctgt     4920

gctatcgtaa gtttgttttg agcactgcat tcactttaaa attctggagg aacaaaggct     4980

gggcacataa tcacaaagcc caggccacac aataattcgg ggttgtattt tctaagaact     5040

atgtattgtt tttagcttat agttaatatt gtatttactt ggaaaaatgt gaataaagtt     5100

aattaacatt acaagctgag a                                               5121


<210>  1179
<211>  3419
<212>  DNA
<213>  homo sapiens

<400>  1179
gcacgcacgc acgcacgcca gcggccggcg gggccgcagg ctcgcgcccg ggctcgcccc       60

gcgccgctcc agaggctcgc gcactcagca ggttgggctg cggcggcggc ggcagctgtg      120

gaagctcagg cgctgcgcgt gagaggtccc agatacgtct gcggttccgg ctccgccacc      180

ctcagcttct cttccccagg tctgggagcc gagtgcggaa ggagggaacg gccctagctt      240

tgggaagcca gaggacaccc ctggctcctg ccgacaccgc cctccttccc ttcccagccg      300

cgggcctcgc tcggtgctag gctactctgc cgggaggcgg cggcggctgc cagtctgtgg      360

agagtcctgc tgccctccag ccgggctcct ccaccgggcc ttgcaggggc cgagagagct      420

cggtgcccgc ccttccgctc gcctttttcg tcagctggct ggagcagcat cggtccggga      480

ggtctctagg ctgaggcggc ggccgctcct ctagttccac aatgtccacg ggcggagact      540

tcgggaatcc gctgaggaaa ttcaagctgg tgttcctggg ggagcaaagc gttggaaaga      600

catctttgat caccagattc atgtatgaca gttttgacaa cacctatcag gcaacaattg      660

gcattgactt tttatcaaaa actatgtact tggaggatcg aacagtacga ttgcaattat      720

gggacacagc aggtcaagag cggttcagga gcttgattcc tagctacatt cgtgactcca      780

ctgtggcagt tgttgtttat gatatcacaa atgttaactc attccagcaa actacaaagt      840

ggattgatga tgtcagaaca gaaagaggaa gtgatgttat catcatgcta gtaggaaata      900

aaacagatct tgctgacaag aggcaagtgt caattgagga gggagagagg aaagccaaag      960

agctgaatgt tatgtttatt gaaactagtg caaaagctgg atacaatgta aagcagctct     1020

ttcgacgtgt agcagcagct ttgccgggaa tggaaagcac acaggacaga agcagagaag     1080

atatgattga cataaaactg gaaaagcctc aggagcaacc agtcagtgaa ggaggctgtt     1140

cctgctaatc tcccatgtca tcttcaacct tcttcagaag ctcactgctt tggccccctt     1200

actctttcat tgactgcagt gtgaatattg gcttgaacct tttcccttca gtaataacgt     1260

attgcaattc atcattgctg cctgtctcgt ggagatgatc tattagcttc acaagcacaa     1320

caaaagtcag tgtcttcatt atttatattt tacaaaaagc caaaatattt cagcatattc     1380

cagtgataac tttaaaaatt agatacattt tcttaacatt tttttctttt ttaatgttat     1440

gataatgtac ttcaaaatga tggaaatctc aacagtatga gtatggcttg gttaacgagc     1500

ggtatgttca cagcctactt tatctctcct tgcttttctc acctctcact tacccccatt     1560

ccctattacc ctattcttac ctagcctccc ccgacttcct caaaacaaac aagagatggc     1620

aaagcagcag ttctaccaag cccattggaa ttatccttta attttacaga taccacttgc     1680

tgtaggctac ggaccaagat gtccaaaatt attcttgagc actgatataa attacggtct     1740

tctttgaggt caaaattcag ccatcatggt aggcagtgct tgaatgagaa aaggctcctg     1800

gtgcatcttc aaaatgagtc ctaaagaaca tactgagtac ttagaagtag aagaacataa     1860

gatgtatttc tgactaaaac aaatggctct ttcacatgtg ctttattaga ctctgggaga     1920

gaaaattaac caagtgcttc agaacaggtt tttagtattt aattcttcac ggtaagaaaa     1980

tgaagttcta atgaactgtt tctcccaagg ttttaaaatt gtcaagagtt attctgtttg     2040

tttaaaaaat aagaaacctc tttaagcaat agattttgct tgggttttct tttttaaaaa     2100

cataatactg tgcaggcaag gcactgtaaa agttttaatt ccttccagaa gaaccagtgg     2160

aagaatttaa atttggcgct acgatcaaaa ctactgaatt agtagaaata atgatgtcta     2220

aagcttacca acaaaagaac cctcagcaga ataacaaaaa ctttgctcag gacatttgag     2280

gtcaaattga agacggaaac cggaaaccgt tttcttgtaa gcccctagag gcagatcagg     2340

taaagcatac atagtagagg gaaaggagag aatggaaata aaactcaata ttatgcagat     2400

ttatgcctta ttttttagca ttttttaagg ttgggtcttt caggctggtt ttggtttgta     2460

ttagatctgt atagtttaat taactggtga tttagtttta tatttaagct acaattaatc     2520

ttttttcttt ggtgatattt atttctttgc cttttttttt tttaacaact ttcaatcttc     2580

agatgtttcg ttgaatctat ttagagcttc accatggcaa tatgtatttc ccttaaaaca     2640

ctgcaaacaa atatactagg agtgtgccct tttaatcttt actagttatt gtgagattgc     2700

tgtgtaagct aataaacaca tttgtaaata cattgtttgc aggacgaaaa cttctgagtt     2760

acagctcagg aaaagcctgc tgaatttatg ttgtaagcat tacttaacac agtataaaga     2820

tgaaaagaca acaaaaatat cttcatactt cctcatcccc tcattggaac aaaaccttaa     2880

actgggagaa ccttagtccc ctctctttcc tcttcctcct ccacttccca cttattgtca     2940

ccttgtaata ttcagagagc acttggatta tggatctgaa tagagaaatg cttacagata     3000

atcattagcc cacataccag taacttatac ttaaagatgg gatggagttg taaagtgctt     3060

ttataataca atataattgt taaaggcaag ggttgactct ttgttttatt ttgacatggc     3120

atgtcctgaa ataaatattg attcaatatg gcagatgggt catattcttt atttggaaga     3180

agttgtgact tctgacatgg gtgtgattgt cttcctacac tgttgcattt gattcttttt     3240

atgtattttt aagaaagtaa ccagttatac tgcttttaat attgattggt ctttttattt     3300

ggcttggagt tcttcaaagc attgaagtgt gttcatagtc caggtttttt ttttaataaa     3360

cacaattttg ctgccaaaaa tatataaata aaacacgaaa gaaaacaaaa aaaaaaaaa      3419


<210>  1180
<211>  5450
<212>  DNA
<213>  homo sapiens

<400>  1180
attggctgtg ggagccaccg tcccgcctcc cagcgactct cggcggtgcc ggagtcgggt       60

gggttggcgg ctataaagct ggtggcgaag gggaggcgcc gcggactgtc ctttcgtggc      120

tcactccctt tcctctgctg ccgctcggtc acgcttgtgc ccgaaggagg aaacagtgac      180

agacctggag actgcagttc tctatccttc acacagctct ttcaccatgc ctggatcact      240

tcctttgaat gcagaagctt gctggccaaa agatgtggga attgttgccc ttgagatcta      300

ttttccttct caatatgttg atcaagcaga gttggaaaaa tatgatggtg tagatgctgg      360

aaagtatacc attggcttgg gccaggccaa gatgggcttc tgcacagata gagaagatat      420

taactctctt tgcatgactg tggttcagaa tcttatggag agaaataacc tttcctatga      480

ttgcattggg cggctggaag ttggaacaga gacaatcatc gacaaatcaa agtctgtgaa      540

gactaatttg atgcagctgt ttgaagagtc tgggaataca gatatagaag gaatcgacac      600

aactaatgca tgctatggag gcacagctgc tgtcttcaat gctgttaact ggattgagtc      660

cagctcttgg gatggacggt atgccctggt agttgcagga gatattgctg tatatgccac      720

aggaaatgct agacctacag gtggagttgg agcagtagct ctgctaattg ggccaaatgc      780

tcctttaatt tttgaacgag ggcttcgtgg gacacatatg caacatgcct atgattttta      840

caagcctgat atgctatctg aatatcctat agtagatgga aaactctcca tacagtgcta      900

cctcagtgca ttagaccgct gctattctgt ctactgcaaa aagatccatg cccagtggca      960

gaaagaggga aatgataaag attttacctt gaatgatttt ggcttcatga tctttcactc     1020

accatattgt aaactggttc agaaatctct agctcggatg ttgctgaatg acttccttaa     1080

tgaccagaat agagataaaa atagtatcta tagtggcctg gaagcctttg gggatgttaa     1140

attagaagac acctactttg atagagatgt ggagaaggca tttatgaagg ctagctctga     1200

actcttcagt cagaaaacaa aggcatcttt acttgtatca aatcaaaatg gaaatatgta     1260

cacatcttca gtatatggtt cccttgcatc tgttctagca cagtactcac ctcagcaatt     1320

agcagggaag agaattggag tgttttctta tggttctggt ttggctgcca ctctgtactc     1380

tcttaaagtc acacaagatg ctacaccggg gtctgctctt gataaaataa cagcaagttt     1440

atgtgatctt aaatcaaggc ttgattcaag aactggtgtg gcaccagatg tcttcgctga     1500

aaacatgaag ctcagagagg acacccatca tttggtcaac tatattcccc agggttcaat     1560

agattcactc tttgaaggaa cgtggtactt agttagggtg gatgaaaagc acagaagaac     1620

ttacgctcgg cgtcccactc caaatgatga cactttggat gaaggagtag gacttgtgca     1680

ttcaaacata gcaactgagc atattccaag ccctgccaag aaagtaccaa gactccctgc     1740

cacagcagca gaacctgaag cagctgtcat tagtaatggg gaacattaag atactctgtg     1800

aggtgcaaga cttcagggtg gggtgggcat ggggtggggg tatgggaaca gttggaggaa     1860

tgggatatct ggggataatt ttaaaggatt acatgttatg taaattttta tgtgactgac     1920

atggagcctg gatgactatc gtgtacttgg gaaagtctct ttgctctatt tgctgacatg     1980

cttcctgttg tggtctggcc aatgccaaat gtactcgaat gatgttaagg gctctgtaaa     2040

acttcatacc tctttggcca tttgtatgca tgatgtttgg tttttaaaca tggtataatg     2100

aattgtgtac ttctgtcaga agaaagcaga ggtactaatc tccaattaaa aaatttttta     2160

acatgtaaga attttgtact ttgaacaaca agattacaga aagtacctgt ggtttttgga     2220

aaacatttct agcttgggga atgtgacaac attccccagt gtggtaaaat tggggtaaaa     2280

tgtggtaaaa tgtgatacgc acaaaccctt tgaaaatagc aaaacaaaca tgcccttttt     2340

ctaaaattga taaatcctaa agaggaagaa aagagctggg acaataaaac actggctctg     2400

gaatctggaa tgttaagtcc aggccagcag tgacaaaagt tattgtaatg acctctgaac     2460

agagaaacac tgccattgaa gaggcttctg gtatagaaaa catggtacat tcaggagctg     2520

tgaatatagc tctaggtgtg ctcctgaatc agttcatggt agattatgct gaacaacagt     2580

gagatgttat tggaggtgtg gatgagggag tttgttgttg cagtccttct ttgcacctta     2640

ttttaaagaa taaatgaaac atttttctgg ttactttttt aaaaatttaa aatggaaggg     2700

aagaataggg gcagggcatt attaggctat ttctgatgct tcagtgttat aaattcaaca     2760

tagaggctga caacctaaat tcatggtgta acacagctct tttccttttc cttttttttt     2820

tttttttggt atctgttcaa tgaaaataag gtatgaccca agtttttacc tagtctgact     2880

agaagtattc cacttcaagg tctgaagtag gacttttacc ttaaaaaaca acaacaaaca     2940

aaactatcac acaggataga taagaagatt ggttaaacag ttttgtgtag atctttttgg     3000

tgctgaacta tgacatgagc cttatagatt gtaaaatagg gatagttgga actaatgtac     3060

agaactaaat tttttaaact ttatttgctg ttaaattctg tgaagtttca gttatctaaa     3120

ataaatatac acaaatatga aatataatgt ttcagattgc aaggtaatat gtaatagtag     3180

tgtttgtaag atactcttgt ctaatattaa ctagtagtat tttgatttgt acagtcataa     3240

tttgttaaaa tgacttcatt taacattcac tgatgtagat taataatgta agttctgatt     3300

taaagaatgg tggcaaaatg gtgcatgtaa tacttttgca agtgttgggg agatcggtat     3360

gttttgaaaa gagtaattta acttttgggt gccaggaaat gggttttctc aaagtccatt     3420

gccggcaatg ggcaggcctg caaatactgg cacagagcat taatcataca ccttattaac     3480

ggtgaggtga ataactttga aataaagttt tagagaaatg tttcagatac ttgagtattc     3540

tttttcactc ttgaactaac aacttcggca agaaatcagc taatattcta tttttaaata     3600

tgggcattaa tttcatttca gttcgttcac tcattccatt catttatcat ttcacaaaca     3660

tttgaaatcc taatataagc aaggtgctct gtttaaggca gaaatttgaa aatgtacaag     3720

atatatggtc ttgtctttaa ggagctgttc atctagaatg gaggaattta cactgataat     3780

tattcctaca cttgaaacaa agaaattaac tctcaaattg cgtggcaagc atatatagac     3840

tttgctataa atatttatga aatgagttac tgttttcctt aaaaaagcta agactaaggg     3900

ctggcaatca aataagagca aatttagtgg tgaacgtaga actgcccact accagctaga     3960

gtctccaacc taaaagtccc atgttgctag tgatccccag gggttttata gaaggaatcc     4020

ctgcattggc agtaattttg gattagatga tccctaagag caccatcaag tcttaggatt     4080

ctatgaatta ggaaataaac caaattatat attttctaat actgatcagc tcatatttta     4140

tcatcatgtc atgtctggct ttcatactta gtcataattt actttctggg tcatttagag     4200

gctagcgttc tctaaggtca cttctgcttg cacattgtag gatattattt agtatggctt     4260

taagaattca atctttcccc ctctccttta tggaatgtgt gtttcctcta tttgtacact     4320

taaccttttg tcctaagttt ttatttttat ggatactaat gagtaacttt gaggttgaca     4380

ctagacccaa acagatgcaa acagccactt tctgtcctct tgtgacacag ttgaaacact     4440

ttatctcttg tctgctgttt ggagtgtcct gaaagaaaca ctgaagtggc agtcaacaga     4500

gcaagggtaa caggatcttt aaataattta aagttgtctg atcttgacat aaaagtgaac     4560

cctttcttta aaatttctag caactgctct taagtcatag gttcctcatt ttttctttgc     4620

tggtagtggg agaaaatagt tgatctgtga tttttgtttt catctcccca aactatgtta     4680

taaaggcagt aatttgatgc tgaagattat gattagaaat cctcagatgg gttatatatt     4740

ggggctttat cttttaatat taaaaagaat gtctttcctg gactacttta ttcagtagta     4800

agcactattc attctatgta tattccttat tcagccttgc agactcctgt gggatctgat     4860

ctcttcctgc ttcaactcag taccatactc accaaggctt agtatgtctt cacccactct     4920

cccttctctt gcattcctca aacatgctga gtttattcca gccttaagcc tttgatctac     4980

gcatcagaaa tgttgggccc cacttcagat cttctctgcc ctgccttcta ctccagtcac     5040

tgctgtggta actaattcca tgaagtcttt gaccaggttc tcagagaata tgatagtacc     5100

tctctttgga ttctagctgt atacctttca cttcagcctc cctgacgtgg aatgtctgca     5160

gaacttgttt ggtactccca attgcacagc ccaaaggtgc aggggagtta ggtgcccatg     5220

gggccatcct tgacctaggt ggaaagttgc tagtggataa ctgattactc ttttcatcac     5280

ctgggcagac agttctgaaa tgcatttcgt aagtctcctc aaaagaggag gagacttctg     5340

tggcgggttt ggcaataacc atccttatat tggctttcct cttttgtttc actcctgtgc     5400

atctctcttg catcctggga tcgcttctca aataaatgac tttcattcaa                5450


<210>  1181
<211>  12815
<212>  DNA
<213>  homo sapiens

<400>  1181
gcggcagtag ctgtagcagc ttcagcgaag ccggagatgg gcagagagcg cgcgcggcgc       60

agcagctcca gattcactgc tctcccctgc agctccccgc gcccccgccg ctgtcgctgc      120

ctcggtgtcc cccagcccca gtcgcgctct taggacagcg ccgccaccgc cgcctggccc      180

tgcctgcctc ctgcgccgcg cagccctcgc gagcgccccg gatggcgctt tacccctagg      240

accgatttag aatgtaataa ctcaaggatt tgataataca gtgaagtagt ataacaactg      300

tctacgtgct tcccatgata tgttctctat attgaaaaat tatgacatca acatccaaag      360

gaattcttcg cccattttta attgtctgca ttatcctggg ctgtttcatg gcatgtcttc      420

tcatttacat caaacctacc aacagctgga tcttcagtcc aatggaatca gccagctctg      480

tgctgaaaat gaaaaacttc ttttccacca aaactgatta ttttaatgaa actactattc      540

tggtgtgggt gtggccattt gggcagacct ttgaccttac atcctgccaa gcaatgttca      600

acatccaagg atgccatctc acaacggacc gttcactgta caacaaatcc catgcagttc      660

tgatccatca ccgagacatc agttgggatc tgacaaattt acctcagcaa gctaggccac      720

ccttccagaa atggatttgg atgaatttgg aatcaccaac tcacactccc caaaagagtg      780

gcattgagca cttgtttaac ctgactctga cttaccgccg tgattcagat atccaagtgc      840

cttatggctt cttgacggta agcacaaatc ccttcgtgtt tgaagtgcca agcaaagaga      900

aattggtgtg ctgggttgtg agtaactgga accctgagca tgccagagtc aagtattaca      960

atgagctaag caaaagcatt gaaatccata cctacgggca agcatttgga gaatatgtca     1020

atgataaaaa tttgattcct accatatcta cttgtaaatt ttatctttcc tttgaaaatt     1080

caatccacaa ggattacatc acggaaaagc tatacaatgc ttttctggct ggctctgtac     1140

ctgttgttct gggaccatct agggaaaact atgagaatta tattccagca gattcattca     1200

ttcatgtgga agattataac tctcccagtg agctagcaaa gtatctgaag gaagtcgaca     1260

aaaacaataa gttatacctt agttacttta actggaggaa ggatttcact gtaaatcttc     1320

cacgattttg ggaatcacat gcatgtttgg cttgcgatca tgtgaaaagg catcaagaat     1380

ataagtctgt tggtaattta gagaaatggt tttggaatta aaatttttca tcacttgcac     1440

acttgataaa tattttgatg agatatcatc caagtattga ggataagaag agatgcaaca     1500

tactactttt gtgtcacaat ttatttttat caccctctct agggtaacgt gtatattttg     1560

gtggagattt ttaaaagctc agcatgagca atcattccat tcggttttaa attatcctgt     1620

atatacctaa ttatgtgcac tggagagtaa tttattcttc attatcattt gtaaacattg     1680

ttttttcaca tttttgtagt tgtccataat gtaagcttgt ggtttgatta ttgtttccac     1740

actgatcagc tgtttaatct atttgggaaa tgaagatgca catcttaaag tatgaaaaat     1800

tttcactaag tattacaatg tctagttcca actttgcata ctataacaga ggaagaacat     1860

gttgcgattg aattctaacc tctttgactc cgaagatgaa tgaagtgtat aactgtctct     1920

atttgatcta ttttttttac ctgtttatca catttgtgaa ggtgaaatta ttcatggagt     1980

gaataagaaa gatatgaagc agaactgttc tattcgggaa gctattagac ttctcattta     2040

ttttcattaa gctgatttgc agctacttat tctcatggtc ttaaattaaa ttattcaagt     2100

atttttaaat atccaatttg ttgtgatttt cagcacctgg gaagtaatcc caataatact     2160

ttagaaaatc taagacagtt ctttctgcta ctgatgacac tcattgtcat aataaaacaa     2220

ataatttcct caaataacaa agaaaaatga tacctataaa tatatttata aatggtgtca     2280

tttatgaaca atgtttaatt atgtatcaat ttaagatttt tttctgaagc cctaatattt     2340

aaaatggtct tattttacca tatggatata agatttggct cataatgatg agccctatca     2400

tttgatttga gttctatcat ttaagagagc ctaaataaaa ttatcatcaa ggtattaaat     2460

ataagacgtt aaatataata aagtggggat atatagaaaa cacacagtgt tagcacacag     2520

taagatctca atgcacattt gttggatgaa taaataaatg caattgaatt cccagaaaaa     2580

tgattgtttc aaggaagtga cagttctact ttagaagtac taattggaga tgacttttat     2640

atcccatttt ggtaattatt catacatagc acatatgacc atgatgttca gggctttata     2700

gaaccaaata aacctaccat tacatgaaaa ttttgaagag tatattcctg aacttgcagc     2760

tgcctatagc attctcctcc ataaggctag aggagagctg gatataagca gagatcgtag     2820

gtgaaaaaag atgggccatt aaggattctt caaggaaaac attcctcaaa atgatcttta     2880

gtgcctttat tcctttcagg ccaataatcc acccaaaaat tagaatgttc tgagacatcc     2940

atttgggtct atttgtgact tattcgtatt acaaattgac atcagcaaaa ttcaaaaaga     3000

attcagtaaa aagggcatag atccagctat ccagactatc ttgtgagaga ataagctcac     3060

cccagcacca gaaagatttg agcagaggaa tattcctgta atgaatagag gattgtttga     3120

ttctcaggta tatttcttaa gccaagattg aatgcagtgt caggcactgc cttaacaccc     3180

acagagataa gatgaacaag gtactatcac tgcctaaaat gagcttacaa ttaagtggat     3240

agacatataa aagcttcctt tcaattcagc ctgagactgt ttatatgcat gtgctactcc     3300

gaatgacgtt tgtatgggtc aatgctgatt taatggggaa aaaaagtaga aaatttcccc     3360

aattgcttag ctgtttgaca tgtttctgag ctgcaaactt tgtcaactct tttgacccaa     3420

catattattc tctccgtatt atctcttcta accacaatgc attaagaaat aatattttta     3480

tgtggatgtc ctcctcaata agtaaagatc tccatccata tttaattaat tggtaagaca     3540

gtcaaattca tacatttaca tttactttgt caaatttttt ggtctataaa aagcatagag     3600

atctaaagag gatacactgc taacaagttt agaaagcacc tgcttttttt tattattatt     3660

atttttgtga tagagtcttg ctctgtcgcc caggccggag tgcagtggtg cagtctcggc     3720

tcactgcaac ctcggcctcc caggttcaag tgattctcct gtatcagcct cccgagtagc     3780

taggattaca ggcgtgtacc actatgcctg gctagttttt gtatttttag tagagatggg     3840

tttcactgtg ttggccaggc tggtcttgaa ctcctgacct caaatgatcc acttgcctca     3900

gcctcccaaa gtgctgggat tacaggtatg agccactgtg tctggcccac ctgttttttt     3960

tgaaggcaga aaaacattca atattaaaag cattcaatat tatttcaacc tgccttggct     4020

ctagtgaatg ttcatgattt gaaagaactg aaagacctaa aggcagtgtc tctattgttg     4080

actacaaatg taggctcttt gttggactat gactataatc acacactgat aatatgacgc     4140

aagtagaggc agtactacta agtatctagc aggtgctttg aaaccccatt actaagtccc     4200

agaagactgt ttcctaaatt tgaagtggaa gaattaaatg actcaatgga accctttagc     4260

tgtgggtcca ttgatgtgtg agttttagag ctggaaggaa ttataatttt gttgtttata     4320

attgctataa tatagaaatt ataattgctt ttctttctac ttatgagtta actagatcca     4380

gagatattta ttcaagacac acattcacac acacatacac acacacacac acacacccca     4440

cagctagtga caatagttaa gatttggatt taaggatcct atctttcttt atcccacttt     4500

cttttcaatc gcattcataa cttattatag aattatgtct caatttttac aaatgtgaat     4560

gtcttattgg tatttttagg gcctatagaa tggtacacct catgtagaag aacttcgact     4620

tttgaaggta tacaataaat aaaacatcaa acttgttagc attcgttctg gtttaaatat     4680

tttaggagtt gagttcagca gaaggaaatg ggctatcact acatttaagt gaaatacaac     4740

cctcaagaaa gtgtatggtt cacagccact cctttaataa atcctgtggg ttgcaattct     4800

ttgtaagaaa ctcatgaaaa agatatattg attcaacaaa attggtttgc tgttgattat     4860

acaaaccaat aattatgcct agaattaaat tgtggacaca aaaaagggaa cagaccattt     4920

aaaatgtttt atttcaaaat atcgaaaagc tattaccttc aatactctaa atatttaaat     4980

attaattatt gtagacatca gtaagaataa ataaatgtta atcattatag accttactaa     5040

taagaatata tactgaattg tccacatcca gagtattaca ccctgaacaa gaaagacatg     5100

agagcctgac agtcatatat attatgacag ctgtatatct gacaatatga agtagaaact     5160

gaaaaaaaaa atcatcttag tgggaaacaa atacatgctt aaaattgtta tatttactgt     5220

aaaactcctg ataatcttag attgtgcaga aatgtttctt attttgaggg gcttagaaag     5280

ctcagcgcat ttgatgtata aagcaacaga atatttagga attatttgcg gaggctttaa     5340

attcttacct ccaattggag gttaaatatt aaaagaatag gaaactatgc ctctgatatt     5400

ttttttgtca gcctattttt aaactagatt ccatgagtct taaggtaata tcctagaatt     5460

ttttttttgc gtgaattaaa gttaccacaa atttcaggtc cttaccttat gactgtgttt     5520

gatcatatct ttgagttccc ttgaactctg atctcatttt gagaaacatt ttgagaaact     5580

tcttaacaat tacaatcgag ctgttaaata taacaaacat cagaatctaa aggataagca     5640

cagtgcctaa tgtacaggag ggtcatatca aatacttgtt gaataaatac atgaatgtga     5700

taagtggtcc tgtaaaatat tttttaagag tagtgacaat gtttattggt accaattgga     5760

gatgatattt tatatttatt ttgttagttt gtcacctgga tgcaaaagga aggcatttta     5820

attcctttct atcttacaac attgtaaagc atcaaaagaa gtaacatctc aagaaagatt     5880

agaaaggatt tggatcacgt taacattcta tgcaaatatt agtaacatat caactgtttc     5940

taaaaggaaa gaaaattagt atttaaggag agtataaagt gcgagcactg tgaagggcag     6000

atatctatta ccaaaccaca tggagagaaa tatagtctct ctcctaactt cattccattg     6060

tattgcaatc agtcaattaa ggtgattttt tttttctgga tgtctcaatc tagagatttt     6120

gtagcatttt gcaaatgggt atgcttcact actatccaca gtgttctccc ctttagtaat     6180

tcatattgaa tatatccata ttcatatgca ttttataaaa cagttaacag aatctaaata     6240

agatatagcc ggctaaatct ggaatgtgag tgctacccta ggttattagt tcaacaaact     6300

aattttgaga gagccactta acctctctgg accttgtttg taagctttct tctagcacta     6360

ttactcttat ctaagatcga aattgatata tgcatgaaat tcctaatgga atttcaatgt     6420

ccatctcaaa gtaatttttt aggatattcc atacagattt ccttctcatt tctctgtgta     6480

gatatttaaa gtatgaaatt gattatttaa actaatatgt ggaaagaacc taatccagag     6540

cttggaatat agaaagtgct caattaactg acattcctcc tgtatttcct ccctcccctt     6600

agttgtctat gacttttgaa ctcactgctc actgacatct taattgcctg cagaaaaatc     6660

aatcatattt taggcattat tttgaaatat tttagagttt tctgtactat tcaaactctt     6720

attacaaaaa tctaaagata tttattgatg caaaaaattt agggagtcat tggaaatacc     6780

tgaggcaatc ccaggctaac aataaaatag cataatttta agtaagctag attgagttca     6840

tttgaacatt tagttatttt ttagctcata gttaacatat gtccatgcat ttgatttact     6900

ttaaaaatat tttatttaaa aataacctct caaacaccag ttgctttctg tcagttttac     6960

tcaaagcatg cttcctaggt cacctgacct agaatcacca gaagtgttaa caataccgat     7020

ttctgggctt tgagccatga aattagaatt tcttcaaata atccatgccc ccccgtcacc     7080

caaaaaaaga gcatgctttt aatacatttc caaaattatc ctgtttctgc tataactggt     7140

gaaccatcct gtcctaaact agcagttctc aaacatgcat atgcctttga aacttcctag     7200

atcatctaca taaaaatcat ttgaaatatt gttaataata cacagcttct gaatctctgg     7260

gtgtgagatg ggaccaggaa tcttatttta aaaatctccc cagatggttc tggtgtcctg     7320

ctagttttga ggttttcatc ccacctgttt agatgggtag tattctatta aatatgaggt     7380

attacctttc tttagttcac ctggaatctt cttaaatata tcggtaaagt attctacttc     7440

aaaatccaag acattttgta tacctaatta tttcacacaa gagcgtggaa ctcaccagtc     7500

ttgtgacttg gggcaggtta tttatagtct ccagacactt tttccagttg cgagttgctt     7560

atagtagttc gcgaacctga atgcacatta gaaccatctg gagaggcttt aaaattgcag     7620

atgtccaaac cccacctcca gagagctgat ctatttagtt tgaggaagag cccagaagtc     7680

taacaggtgt aaatgttcca caggtaatac taatgcaggc atacctcagg aaatcaccag     7740

ttctcgtctt ggaggaacta ttaggaaaat aaaagattat atatcttgaa aaaaatctct     7800

aatttgcttt ctaggttcta actgcatgtt tatattttgc aacaggaaag actggtctag     7860

acaattacta ggatatatgc ttctgtgatc tgcttttcta ttgtatgtgt ttaagagacc     7920

acattcttgg gttccaaagt ctccttgtct gataggtaat ttgcaattga gatatggcaa     7980

agaattgtag catccaaatt tttgacaact acagatttag aattgaatcc aaggtctgcc     8040

attcactagc tatgtgcaag ttactcaact tctcttatcc tcagattttg cagctgtaaa     8100

gcagaggtag catatttctg agaaattata ttcaggtgac tagatatgtg ttcaagtgtt     8160

atcttttatt cttataaaag ataattgtga ggaatccagt gctattttca caattttaat     8220

tctaaaactc tgaagacatt aaacaggcag tttgtaggaa tcattgaaat tttatacaag     8280

ccgaaggaac aacattcagc aaaacggaaa caaataaata cagcatggaa gcatatattc     8340

atgtttccca taattactaa gttacggaag gggtgtgagg agctggcagt ggtggtgaat     8400

aggcattgtt tgcattacta aatatatata ccatttctta agataattgg aactcaagca     8460

gtcctaattt tctctccctg ttatgagcaa tcagtaaatt tgtagtcaat ttaacttatt     8520

atcagttggt atagcgcatg tcacagaata ggatagcaag aagattctca gagatcattt     8580

tctggtaaag aaaaaggcct agcaatattt aacagtttga cttaatccat cacttcagct     8640

ggtccactag ttttgacaca ggactagtta atgatttgtt aggaagtctc catctactct     8700

taaactaatt taaaaaaaag ctaaaagttg cttttaatat gttagggtat aacttcaata     8760

aacaggagta tttatctagt ggttcagaaa taaaataatt gttagccagc ctgtgattaa     8820

ggctaccata attgcataat aaatagcttt gacgtgaata atctcagttg ttcaagtgta     8880

caaatttaaa gctgtactat gttagaataa aaaagtaggc tcaaggaaaa tttctatttt     8940

tctatatgaa aaagagaatg atattcaaaa tagtattttt aagtagtttc taattgtgtt     9000

cctttaaaga gtattagaaa tgtctgttat gtcagtaaca ttagaaaact tcaaaaactg     9060

atttattttt ctgagttctc tggaaaccaa acaattttga attagttgtg taagtaaagt     9120

aagttaagtt atagcttgct ggaattttat tgtggaaaac aaatatagat tttatctgaa     9180

aaattttaag ggccaattct acagaaagtt atgctaacat gctaactttc cacacatggc     9240

tgcattccat tttgattaat gagggttcag gaaatagaaa ggcagtctct gcagaagcag     9300

tatccaaagg ctaaattaac aacccaggac taccactcat tatgtgagaa atatgggcca     9360

gagttacaat atcacatctc cagtctcaga ttggcctcat tagccacctt cagttcctta     9420

aatgagataa tcctgaagat gccatccttg tccaaggtga gattgccaga ggatatgagc     9480

tcatctagga tggaatacat gtctccaggg actgtaatga gatcaggctt ttcatttact     9540

ggttttctgc ctcaagagtc cttaagcaaa tgaagattat ctgattgtct atgtaaacct     9600

ggaagtagtc tactttttag ataaaagata atctatcttg aatatttcat atgtgatttt     9660

aaaataatta atcaaaaaac aaagactatc atatttgaga acaagatttt acttagaagg     9720

gaaaaaaaag aactttcagc ttaatcgggg ttaagggagt aattgtgaca atataaaatg     9780

gcattgttat agaatcccta aaaggtaaat aatgtatgag atgaaggtag gaagtaatgt     9840

gtgcttgcag aaatgcaact ggtcaaaatt acttgaatga aattgttgag gttaaacatc     9900

ttcattataa taatatgtct tattctgatt ccaagacaat acgaatgtag agaagagatt     9960

tttaaatgga aaaagtaagg agctaacaag tctgtaccta gattcaagtt cacaaagcgg    10020

caaaaaggag aaaagtgtca acaagaaaca agaagaggag tagtaaacta aggatcaaag    10080

cccaagttcc agttttcaca atctgctgta taattcacta acatttctga gccatagatt    10140

tttaatctgt aaaaggagtg tgatggactg tacattagaa gtacctgaga agctcttaat    10200

aaatcttgat gaattggtta gaaattctaa tttaattagc ctggcacagt gcacaaactg    10260

ccatatattc gtgcagatgt tttcttcttt tcttactgcg catttccatg tggccatgtc    10320

actacaaggg gtggggaaga agttaatgtg taattgcttc aggagctctg aataaaaggt    10380

tgctgaagca aaatactgca atgaagttct gaaaatgaag agttaggact ttacatgatt    10440

tctcttgcct cattccctca agaatgcaca tatagacaca catatgccaa tatctttttt    10500

atgtagttca agtataactt tgaataaaat gacttacatt caaggaaggt caaaactatt    10560

attctgaaac aaaatgtgac aattctagcc attatgtgaa ttgtaagggt cagtaatcca    10620

taaattattt ggatggtaat tgtatgtttt attaatgtga tgtaattttg cactattgta    10680

ttgtcatatt taatcaaact cttaaaaata ccctgaaaca taatgccaaa tgtacagttt    10740

ataggttcgt gttatttctg ataagaattt aattgcattg tgctaatagt tgtttattgc    10800

tattaacttt ctgtgtatgt attattgcga tgcagaccca atagggttat tttaagcaca    10860

ctaattagtc atctggattt ttatagataa aatcacatgt tgatcagaaa tcatttttct    10920

acttattttt ttgtagagta tttttccaca cttgaaaaaa acatgattat tttatatcaa    10980

acatcaactt ttctttaaat cttattttag tagctaatgc atgtttgaaa taagatgtgt    11040

tagaaattat atgactatat taaggttgtg tttatattag gtgaaaaatt gcatgcaatt    11100

ggtgaatcat gcagctttgg ggacatttac actgccactc acacacaggc tctgtctcaa    11160

tccgtatgca tgattcacgt cctttcaaaa gtcccttttc aacatttggt aaagtgaaaa    11220

tgttattcat agtgctaatg agccaataaa caatgctgcg tttctttttt ctaactgcag    11280

catattgtgg taaattttct cccaaaactt tatttttgga gttattgttg gcaataaata    11340

caacaaatta tttgttggca agtgatacaa tttactgtat aacaacttaa tagtacaaag    11400

catgaagatg tgaaaatatc atcttaacca gtttcattct atgaacataa tattctggca    11460

gctttttcta taactgagaa tggtatatct ttttatacac tgcctaaatc agtactactg    11520

ccagtcacct gaggtcaggt ctgcacaaca ctaaattggg caataacata gaacatctag    11580

gcagtcttga cagtcaacca gtgtaatcac taggggaaga aaaagtaggc ctaccctttt    11640

acttattaac ttaagtaata aaaattgtat aaaaatatga atgttggctg cagaggagcc    11700

tttacatgca gataatttga agcagtcttt gaaaataaca aaaattattc catttaatga    11760

agggtttgtt ttgtttagct tttctctttt attcagaaaa catacctgtg cttttgaaag    11820

ggcttaatcc caaacaggta atatgtgtgg atcaatcatc tctcctccca tgaaattaat    11880

cattcatggt aatatattaa ggctggaacg tagctcttag tgacttaaaa catgacagta    11940

agcatttaca ctgttggaag gtaatttcat tgctatgtta ttaaaatgat gggaatccta    12000

tttatacatt tatttattta tttatttaca gaagattggt tccttccagt tcaatttaac    12060

agcttcagtg aagttagtat aatgataaga aaaattgact gtagctatta ttccaagtga    12120

aaatcatgca gctgagtcct gctgcatcct gggagcaaag cattaattca aatgaggagt    12180

agtcagtcct agcactgtag acgccgactt taccaaccaa gatagtgtat gtgtgtgaca    12240

ttcagctaac attgatctag gcacttagtt tgctaccaca ttgttccctt cattgattga    12300

aactgtaaat aacataacac tttaaggcag ctaagcaaat attttaataa gccatgaaag    12360

gcaagatgcc agagaaaatc tgtatattca gctatttgga gaactcgtgt tttccacaaa    12420

ttaaactgga gatgtcattt gaaattttct tcccttaaac atgctgtcac aacatggatt    12480

ccttctcatg gatgtctttc taggcttata aatatatggt gtgattgcta taattttgtg    12540

aaattttatt cagcaattaa tagtgatttc agcaatatgt actaagattc caaggcagaa    12600

ataaatgtat aaaggatttg agcctgtatg tgtaagaaga aactctctct tcagtcatat    12660

ttcctaaatt cagtgtaagt acctcgctga tttagcactg gagttattcc ttgaatgtgt    12720

aaataatgat gttctattct gacctaatga attcctgtaa tgtgaatatt taaaataaaa    12780

gaattcaatt taaatgtaaa aaaaaaaaaa aaaaa                               12815


<210>  1182
<211>  2056
<212>  DNA
<213>  homo sapiens

<400>  1182
aaccgaaaag caacagctga tggcaaatcc gctccggcgc ttgcacgcct cctcggcggc       60

agtctcctgt tgcttctcgg agcttgactg ccctttggaa aaatctctcc gcccctcgag      120

aggagagagg agcagaggac gcgcgcgagc acagagcggg aggacggaca gggagaggag      180

gagagggggt ctgcgcgcgg ccgctaccca gaagccagcg gacggcagca cggagtgggc      240

tgtccccgag cccagccccg agcgagcccc ccccccgccc ccgcaggacg cgcctcccag      300

ccagcccgac tcctaggagg aggggaggcg ggaaagcagc tcaagcctca cccaccgccc      360

tgcccccagc cccgccactc ccaggctcct cgggactcgg cgggtcctcc tgggagtctc      420

ggaggggacc ggctgtgcag acgccatgga gttggtgctg gtcttcctct gcagcctgct      480

ggcccccatg gtcctggcca gtgcagctga aaaggagaag gaaatggacc cttttcatta      540

tgattaccag accctgagga ttgggggact ggtgttcgct gtggtcctct tctcggttgg      600

gatcctcctt atcctaagtc gcaggtgcaa gtgcagtttc aatcagaagc cccgggcccc      660

aggagatgag gaagcccagg tggagaacct catcaccgcc aatgcaacag agccccagaa      720

agcagagaac tgaagtgcag ccatcaggtg gaagcctctg gaacctgagg cggctgcttg      780

aacctttgga tgcaaatgtc gatgcttaag aaaaccggcc acttcagcaa cagccctttc      840

cccaggagaa gccaagaact tgtgtgtccc ccaccctatc ccctctaaca ccattcctcc      900

acctgatgat gcaactaaca cttgcctccc cactgcagcc tgcggtcctg cccacctccc      960

gtgatgtgtg tgtgtgtgtg tgtgtgtgtg actgtgtgtg tttgctaact gtggtctttg     1020

tggctacttg tttgtggatg gtattgtgtt tgttagtgaa ctgtggactc gctttcccag     1080

gcaggggctg agccacatgg ccatctgctc ctccctgccc ccgtggccct ccatcacctt     1140

ctgctcctag gaggctgctt gttgcccgag accagccccc tcccctgatt tagggatgcg     1200

tagggtaaga gcacgggcag tggtcttcag tcgtcttggg acctgggaag gtttgcagca     1260

ctttgtcatc attcttcatg gactcctttc actcctttaa caaaaacctt gcttccttat     1320

cccacctgat cccagtctga aggtctctta gcaactggag atacaaagca aggagctggt     1380

gagcccagcg ttgacgtcag gcaggctatg cccttccgtg gttaatttct tcccaggggc     1440

ttccacgagg agtccccatc tgccccgccc cttcacagag cgcccgggga ttccaggccc     1500

agggcttcta ctctgcccct ggggaatgtg tcccctgcat atcttctcag caataactcc     1560

atgggctctg ggaccctacc ccttccaacc ttccctgctt ctgagacttc aatctacagc     1620

ccagctcatc cagatgcaga ctacagtccc tgcaattggg tctctggcag gcaatagttg     1680

aaggactcct gttccgttgg ggccagcaca ccgggatgga tggagggaga gcagaggcct     1740

ttgcttctct gcctacgtcc ccttagatgg gcagcagagg caactcccgc atcctttgct     1800

ctgcctgtca gtggtcagag cggtgagcga ggtgggttgg agactcagca ggctccgtgc     1860

agcccttggg aacagtgaga ggttgaaggt cataacgaga gtgggaactc aacccagatc     1920

ccgcccctcc tgtcctctgt gttcccgcgg aaaccaacca aaccgtgcgc tgtgacccat     1980

tgctgttctc tgtatcgtga tctatcctca acaacaacag aaaaaaggaa taaaatatcc     2040

tttgtttcct agtggc                                                     2056


<210>  1183
<211>  5313
<212>  DNA
<213>  homo sapiens

<400>  1183
gcggccgccg gcgaggcgag gcggcccgcg ccctgcctgt caggccaccg gcccggcccg       60

cgggctgccc ccgatgcgga ggcgctgtcg ccggggccat gcagcaggcg ccgcagcctt      120

acgagttctt cagcgaggag aacagtccga aatggcgggg actgttggtc tcggccctgc      180

ggaaggttca ggaacaagtg catcccactc tctcagctaa tgaagagtct ctctattata      240

ttgaagagct gatttttcag ctgcttaata aattatgcat ggcccagcca aggactgttc      300

aagatgtaga ggagcgagtt cagaagacct ttcctcaccc aattgataaa tgggccattg      360

ctgatgcaca atctgctata gaaaaacgaa aacgaagaaa tcctctttta ctgcctgtgg      420

acaaaatcca tccttcgttg aaggaagtat tagggtacaa agtggactac catgtatccc      480

tatatattgt ggctgtacta gagtatatct cagctgatat tttaaaattg gctggtaatt      540

atgtttttaa tatccggcat tatgaaatat ctcagcagga cattaaagtg tcaatgtgtg      600

cggataaggt tttgatggac atgtttgatc aggatgacat aggtttggtt tctctctgtg      660

aagatgaacc tagttcttct ggtgaattaa actactatga tcttgtcaga actgaaatcg      720

cagaagaaag acagtatcta cgggaattaa atatgatcat aaaagtgttt cgagaagcct      780

ttctttctga tagaaagctg tttaaacctt ctgatatcga aaagattttt agtaacattt      840

cagatataca tgaattgact gtgaaacttt taggtttgat tgaagacaca gttgaaatga      900

ctgatgaaag cagtcctcat cccttagctg gcagctgttt tgaagatttg gcagaagagc      960

aagcatttga tccttatgaa acattatcac aggacattct ttcaccagag tttcatgaac     1020

atttcaataa attgatggcc agacctgcag ttgctctaca ctttcagtcc attgctgatg     1080

gttttaaaga ggcagttcgt tatgtccttc cacgtcttat gctggtgcca gtgtatcact     1140

gttggcacta ctttgagtta ctaaagcaat tgaaagcatg tagtgaagaa caagaagaca     1200

gagaatgttt gaaccaagct attactgctc tcatgaatct ccaaggtagc atggaccgaa     1260

tttacaagca gtattcacct agacgtcgac ctggagatcc tgtttgccct ttttatagtc     1320

accaattaag aagcaaacac ctggctatca aaaaaatgaa tgaaattcag aaaaatatcg     1380

atggatggga aggcaaagat attggacagt gttgtaatga attcattatg gagggaccat     1440

tgacaagaat cggtgccaaa catgaacggc atatttttct gtttgatggc ttaatgatca     1500

gttgtaaacc taatcatggc cagactcggc ttccaggtta cagtagtgca gaatacaggt     1560

taaaagaaaa atttgtcatg aggaaaatac aaatttgtga taaagaagat acttgtgagc     1620

acaagcatgc atttgaatta gtatccaaag atgagaacag cataatattt gctgctaagt     1680

ctgctgaaga aaaaaacaac tggatggcag cccttatttc tcttcattat cgtagtactc     1740

tagatcgaat gttagattca gtattattga aagaagaaaa tgagcaacca ctgagattac     1800

caagtcctga agtatatcgt tttgtagtaa aagactctga ggaaaacatt gtttttgaag     1860

acaacttgca aagtagaagt ggcatcccca ttattaaagg aggaactgta gtgaaattaa     1920

ttgaaaggtt aacatatcat atgtatgcag atcccaattt tgttcgtact tttcttacca     1980

catatcgttc attttgtaaa ccacaggaat tgctgagctt actgattgaa cggtttgaaa     2040

ttccagagcc agaacctact gacgcagaca aattggcaat agagaaaggc gagcagccaa     2100

tcagtgcaga ccttaaaaga tttcgcaagg aatatgtcca accagtacaa cttaggatct     2160

taaatgtatt tcggcattgg gttgaacatc atttttatga ctttgaaaga gacttggaat     2220

tgcttgaaag actagaatcc ttcatttcaa gtgtaagagg gaaagctatg aaaaaatggg     2280

tagagtcaat tgctaagatc atcaggagga agaagcaagc tcaggcaaac ggagtaagcc     2340

ataatattac ctttgaaagt ccacctccac caattgaatg gcatatcagc aaaccaggac     2400

agtttgaaac atttgatctc atgacacttc atccaataga aattgcacgt cagctgacac     2460

ttttggagtc tgatctttac aggaaagttc aaccgtctga acttgtaggg agtgtgtgga     2520

ccaaagaaga taaagaaata aattctccaa atttattaaa aatgattcgc cataccacaa     2580

atctcaccct ctggtttgaa aaatgcattg tggaagcaga aaattttgaa gaacgggtgg     2640

cagtactaag tagaattata gaaattctgc aagtttttca agatttgaat aatttcaatg     2700

gcgtattgga gatagtcagt gcagtaaatt cagtgtcagt atacagacta gaccatacct     2760

ttgaggcact gcaggaaagg aaaaggaaaa ttttggacga agctgtggaa ttaagtcaag     2820

atcactttaa aaaataccta gtaaaactta agtcaatcaa tccaccttgt gtgccttttt     2880

ttggaatata tttaacaaat attctgaaga ccgaagaagg gaataatgat tttttaaaaa     2940

agaaagggaa agatttaatc aatttcagta agaggaggaa agtagctgaa attactggag     3000

aaattcagca gtatcagaat cagccttact gtttacggat agaaccagat atgaggagat     3060

tctttgaaaa ccttaacccc atgggaagtg catctgaaaa agagtttaca gattatttgt     3120

tcaacaagtc actagaaatt gaacctcgaa actgcaaaca gccacctcga tttcctagga     3180

aatcaacttt ttccttaaaa tctcctggaa taaggcctaa cacaggccga catggctcta     3240

cctcaggtac tttacgaggt cacccaacac cattagaaag agaaccatgt aaaataagct     3300

ttagtcggat tgctgaaact gagctggaat caacagtgtc agcaccaacc tctccaaata     3360

caccatctac tccaccagta tctgcttctt cagaccttag tgtattttta gatgtggatc     3420

tcaacagctc ctgtggcagc aatagcatct ttgctccagt gcttttgcca cattcaaagt     3480

ctttctttag ttcatgtggt agtttacata aactaagtga agagcccctg attcctcctc     3540

ctcttcctcc tcgaaaaaag tttgatcatg atgcttcaaa ttccaaggga aatatgaaat     3600

ctgatgatga tcctcctgct attccaccga gacagcctcc tcctccaaag gtaaaaccca     3660

gagttcctgt tcctactggt gcatttgatg ggcctctgca tagtccacct ccgccaccac     3720

caagagatcc tcttcctgat acccctccac cagttcccct tcggcctcca gaacacttta     3780

taaactgtcc atttaatctt cagccacctc cactggggca tcttcacaga gattcagact     3840

ggctcagaga cattagtacg tgtccaaatt cgccaagcac tcctcctagc acaccctctc     3900

caagggtacc gcgtcgatgc tatgtgctca gttctagtca gaataatctt gctcatcctc     3960

cagctccccc tgttccacca aggcagaatt caagccctca tctgccaaaa ctgccaccaa     4020

agacttacaa acgggagctt tcgcaccccc cattgtacag actgcctttg ctagaaaatg     4080

cagaaactcc ccaatgacct tagccatatg tagtcattga cactggaatg gtatttgtaa     4140

agtttttttt ttaatttatt caaaaaaaga catagtattt tagtactttt tacaaataat     4200

gctcttacaa aaatgctact gatcaaataa gcttttaaga attggaaaaa taaaaataca     4260

aaagtccttc accattatcc tcaggtgatc agtagcattg ccttgtcttg gatcctcagt     4320

gctgccaaaa ggccagtata aagaatttat atttgcactg taaactctgc aaaaatatgg     4380

tttaaagtga catgattgca ctgaaaaggg atagtgcttt tgtgaaattt ttcaaatttg     4440

agtaatagat gcctttttaa ggcagtgaat ttacacaaat atgggagggg tatatggtgt     4500

tactgatttt taaacctctt tgaccatctt ctagttttta cttctagttt ttacatctag     4560

gagaattgtg aataacacca actgttctta aactctttaa tgccatgtct taaatgccgg     4620

tatttgctgc tgaagacaaa aatgaaaagt aggatgaaaa taatagaatg gcactgtaag     4680

tgtttattat tttgtcaaaa tgtaaacaaa gactacataa cccaatgatg gagggaaaaa     4740

gggcatgtat ctcattcaga tgtgcctttt gtttttgcag actatgacgt ctttagctaa     4800

tgaattgcct attgttatgg aaaacagtta atatgccatg tatgtacagt tttgtttata     4860

ttgtatattt aaagatactg ctaataacct atataaattt aagtgacttg aggcctataa     4920

tacaatctgc tactttacta attcataaat tcaaaaaaaa ttctatggca taggaaccaa     4980

ctgccttgcc ttcaagacct agtaactttc tctataaatc tcgtgttaac tgaaattttt     5040

tttaaatata ttttttagat tggtaatatt taaaccagca aatacttaaa gctttattaa     5100

acattttaat cagataagtg agtaaagctt ttatttgcca tttggatgcc ttcgttcaaa     5160

gtgatagagt gttttgctga tagtgctgta gcagcagttg taaagtagcc aaaagccacg     5220

ttgtttattt actggtttgt ggccttttac tgtgctttgt atcagagttc ttaacaagat     5280

taataaatca ccccagtctt aatttttaaa aga                                  5313


<210>  1184
<211>  1394
<212>  DNA
<213>  homo sapiens

<400>  1184
ttaaggaggt gcagtcttat gggagggaca ggggcggagt cagtctttaa aagctgttcc       60

caggtctggc ccgcctgcca caaacgctga gcccaggtgg gagaggtctg gcctatccgc      120

gcctggcagc tgtcggaact ccggagacca caaaggggtt tatggtttac cccctccacg      180

gaaggtcggt ctgatcgcag ctgcgggtcg gggagaggga ccgggggtcc cccagtcagt      240

aggcctcaga acacctcttc agtgccgggg caccagacag cggattttgc attcgactct      300

ccccaaagtg tgccgaacag gttggaagca aaggctccgg tttaagctct gggcttgggg      360

ataaaataca ctttttaagg acccaagttc ctcggcaacg actccagact gggaagacct      420

ttccattttc aggatcgacg cttcacgttg aggggagggc attcaggacg ccctcttaag      480

gcttctccca acccatggcg ctaccaggct cctcacagga ccaggcctgg agcctggagc      540

ctccggctgc cacggctgct gcctcctcat cttcgggacc ccaggagcgg gagggcgctg      600

ggagccccgc ggcccccggg acgctgcccc tggagaaggt gaagcggccg atgaacgcgt      660

tcatggtgtg gagctccgct cagcgccgcc agatggcgca gcagaacccc aagatgcaca      720

actccgagat ctccaagcgc ctgggcgcgc agtggaagct gctggacgag gacgagaagc      780

ggcccttcgt ggaggaggcc aagcggctcc gcgcccgaca cctgcgcgac taccccgact      840

acaagtaccg gcctcggcgc aaggccaaga gctcgggcgc cggaccttcc cgctgcggac      900

agggaagagg caacctggcc agcggcggcc cgctctgggg gccggggtac gcgaccaccc      960

aaccgagcag aggctttggg tacagacccc ccagctactc gacagcctac ctgcctggca     1020

gctatggctc ttcccactgc aaactggaag ccccctcacc gtgctccctc cctcagagtg     1080

accctaggct ccagggggaa ctgctgccca cctataccca ctacctgccc cctggctctc     1140

ccactccata caaccctccc cttgctggtg cccccatgcc cctaacccac ctctaaccct     1200

catggacgca gacctcacgg gacgggcctc atcctccttt tttaatccag cagcatcccc     1260

taccccaggc tgtcaaccct ttctcctgtt ggactacagt tcagaggcag cctgcagtcc     1320

tcccatgata gccagggaga gccgcacaac atacaattat atttttggta gtattaaaca     1380

gttttgtatt attc                                                       1394


<210>  1185
<211>  1752
<212>  DNA
<213>  homo sapiens

<400>  1185
agcgcggtga gtttgaaact gctcgcactt ggcttcaaag ctggctcttg gaaattgagc       60

ggagagcgac gcggttgttg tagctgccgc tgcggccgcc gcggaataat aagccgggat      120

ctaccatacc cattgactaa ctatggaaga ttataccaaa atagagaaaa ttggagaagg      180

tacctatgga gttgtgtata agggtagaca caaaactaca ggtcaagtgg tagccatgaa      240

aaaaatcaga ctagaaagtg aagaggaagg ggttcctagt actgcaattc gggaaatttc      300

tctattaaag gaacttcgtc atccaaatat agtcagtctt caggatgtgc ttatgcagga      360

ttccaggtta tatctcatct ttgagtttct ttccatggat ctgaagaaat acttggattc      420

tatccctcct ggtcagtaca tggattcttc acttgttaag gtagtaacac tctggtacag      480

atctccagaa gtattgctgg ggtcagctcg ttactcaact ccagttgaca tttggagtat      540

aggcaccata tttgctgaac tagcaactaa gaaaccactt ttccatgggg attcagaaat      600

tgatcaactc ttcaggattt tcagagcttt gggcactccc aataatgaag tgtggccaga      660

agtggaatct ttacaggact ataagaatac atttcccaaa tggaaaccag gaagcctagc      720

atcccatgtc aaaaacttgg atgaaaatgg cttggatttg ctctcgaaaa tgttaatcta      780

tgatccagcc aaacgaattt ctggcaaaat ggcactgaat catccatatt ttaatgattt      840

ggacaatcag attaagaaga tgtagctttc tgacaaaaag tttccatatg ttatatcaac      900

agatagttgt gtttttattg ttaactcttg tctatttttg tcttatatat atttctttgt      960

tatcaaactt cagctgtact tcgtcttcta atttcaaaaa tataacttaa aaatgtaaat     1020

attctatatg aatttaaata taattctgta aatgtgtgta ggtctcactg taacaactat     1080

ttgttactat aataaaacta taatattgat gtcaggaatc aggaaaaaat ttgagttggc     1140

ttaaatcatc tcagtcctta tggcagtttt attttcctgt agttggaact actaaaattt     1200

aggaaaatgc taagttcaag tttcgtaatg ctttgaagta tttttatgct ctgaatgttt     1260

aaatgttctc atcagtttct tgccatgttg ttaactatac aacctggcta aagatgaata     1320

tttttctact ggtattttaa tttttgacct aaatgtttaa gcattcggaa tgagaaaact     1380

atacagattt gagaaatgat gctaaattta taggagtttt cagtaactta aaaagctaac     1440

atgagagcat gccaaaattt gctaagtctt acaaagatca agggctgtcc gcaacaggga     1500

agaacagttt tgaaaattta tgaactatct tatttttagg taggttttga aagctttttg     1560

tctaagtgaa ttcttatgcc ttggtcagag taataactga aggagttgct tatcttggct     1620

ttcgagtctg agtttaaaac tacacatttt gacatagtgt ttattagcag ccatctaaaa     1680

aggctctaat gtatatttaa ctaaaattac tagctttggg aattaaactg tttaacaaat     1740

aaaaaaaaaa aa                                                         1752


<210>  1186
<211>  2248
<212>  DNA
<213>  homo sapiens

<400>  1186
gcgagagttg cttttgcgcg cgaactgtaa gtgccagggt ctcagggtca ggtcgcggct       60

ggtcactgtg caggcgcttg ggtgacgcga cgatctcagc ggatctggtc accttcgtct      120

ccccgccatg gagacctcag cactcaagca gcaggagcag cccgcggcga ccaagatcag      180

gaacctgccc tgagacaggg tctcgctctg tcgcccatgc tggagcgcag tggtgtgatc      240

acagctcagt gtaacctcaa acattggggt tcaagccatt ctcctgcctc agcctccgaa      300

gaactgggac ttttagaggg ttgaaaaata ccggccacag accctgaatg atctcatttc      360

tcatcaggac attctgagta ccattcagaa gtttatcaat gaagaccgac tgccacactt      420

gcttctctac ggtcccccag ggacaggcaa gacatctacc atcctagcct gtgcgaaaca      480

gctatataaa gacaaagaat ttggctccat ggtcttggag ctgaatgctt cagatgaccg      540

aggaatagac atcattcgag gaccgatcct gagctttgct agcacaagga caatatttaa      600

gaaaggcttt aagctagtga tcttggatga agcagacgcc atgactcagg acgcccagaa      660

tgccttgaga agagtaattg agaaattcac agaaaatacc agattctgcc tcatctgtaa      720

ctatctgtca aagatcatcc ctgccttgca gtcccgctgc acgaggtttc ggttcggtcc      780

cctgactcct gaactcatgg ttccccgcct ggaacatgtc gtggaagaag agaaagttga      840

tataagtgaa gatggaatga aagcactagt cactctttcc agtggagaca tgcgtagggc      900

tctgaacatt ttgcagagca ccaatatggc ctttgggaag gtgacagagg agactgtcta      960

cacctgcacc gggcacccgc tcaagtcaga cattgccaac atcctggact ggatgttgaa     1020

tcaagatttc accacagcct acagaaatat tacagagttg aaaactctga aggggttggc     1080

actgcatgat atcctgacag agatacactt gtttgtgcat agagttgact ttccatcttc     1140

agttcgaata catttattga ccaaaatggc agacattgag tacaggcttt ctgttggcac     1200

caacgagaag atccagctga gctccctcat tgctgcattt caagtcacca gagacctgat     1260

tgttgcagag gcctagatgc tctgagggcc attcacaatt ctcagggctc agcagtgatg     1320

ggagaacaga ggacagttcc aggataaact gctgcctggg gctgtgggat gaatcagtca     1380

ccccgaatct tggaaaaacc cccttccagg agaggatggg caggcattta aaaagtacca     1440

tttttgtggt tgtttggagc agggatgtac aaaataattt taatgtatta actcatactg     1500

cctgtctttt ataggggaaa aaaataacct tttttatttt aaagttataa ggtttttacc     1560

ttttagttgc ttggatgaca gggaattagc ctaccccatt ttggtctgga acagaagact     1620

ttcaaattta atatggtcca agtgtcttcc tactcaaggt aaacattatc tccaaaatta     1680

catttatgat tctaatattt ggcattgtgt ctgtatctaa tttaaacaga tgttaatgga     1740

cgtctggccg aaactattat acttttataa gatgagctga atcctcttac tttaaaaact     1800

ggtcttttta tttaccctct gtggtagaag agtcaccagc aggttccaaa ttgatgtgta     1860

tgataggaaa aaaaccttaa ttttaaatat aatatagagc cttaaactat gccactgggt     1920

ggcagaggct gtataaaacg cacttgtttt catgcaggag cggggcaagt aaggttgagc     1980

ctgactgtaa acctagaact gcggaaggac tgggactttt gtacaaattt cacatttatt     2040

ttacagcaat catgctgcat ttgtgttagt gttctttata ataaaaaaca aagcagcctc     2100

ctggctggct gtgttacaag tgactcttcc ttagacagct agaaagatgc tgactttgtc     2160

aaacttgcat ttatatgaaa accttctgtc tctaatatca cagaataaac tttctttaga     2220

tgctgttctt tataaaaaaa aaaaaaaa                                        2248


<210>  1187
<211>  2702
<212>  DNA
<213>  homo sapiens

<400>  1187
gcgcgctctg ctcggctgca ggctcaggaa gcggcgcggc ggcacgtgct gggccagagc       60

cccgcgccct gcgtccagcc gccgggtgtg tgcgcccgcg tagcccagcg tcgcgcctcg      120

gcgcccccac gcgcccacgc agcggcgcgg ggacccgggc gggggcagag ggagggcccg      180

gcccagggag gagaaggggc cggtcctccc ggcgcaggca gcagccgcgg cagcccagga      240

ggcggaggca gcggcaacgg cagagacagc aacgtgcccg ccgcagtcag cccggcctcg      300

tcggacccgc accggcccgc ccgcccgccc gcaccgcgtc ggggcgccct ctccactgcg      360

cgcggtacaa ggaaatggta gaactagtga tctcacccag cctcactgta aacagcgatt      420

gtctggataa actgaagttt aaccgtgctg acgctgctgt gtggactctg agtgacagac      480

aaggcatcac caaatcggcc cccctgagag tgtcccagct cttctccaga tcttgcccac      540

gtgtcctccc ccgccagcct tccacagcca tggcagccta cggccagacg cagtacagtg      600

cggggatcca gcaggctacc ccctatacag cttacccacc tccagcacaa gcctatggaa      660

tcccttccta cagcatcaag acagaagaca gcttgaacca ttcccctggc cagagtggat      720

tcctcagcta tggctccagc ttcagcacct cacccactgg acagagccca tacacctacc      780

agatgcacgg cacaacaggg ttctatcaag gaggaaatgg actgggcaac gcagccggtt      840

tcgggagtgt gcaccaggac tatccttcct accccggctt cccccagagc cagtaccccc      900

agtattacgg ctcatcctac aaccctccct acgtcccggc cagcagcatc tgcccttcgc      960

ccctctccac gtccacctac gtcctccagg aggcatctca caacgtcccc aaccagagtt     1020

ccgagtcact tgctggtgaa tacaacacac acaatggacc ttccacacca gcgaaagagg     1080

gagacacaga caggccgcac cgggcctccg acgggaagct ccgaggccgg tctaagagga     1140

gcagtgaccc gtccccggca ggggacaatg agattgagcg tgtgttcgtg tgggacttgg     1200

atgagacaat aattattttt cactccttac tcacggggac atttgcatcc agatacggga     1260

aggacaccac gacgtccgtg cgcattggcc ttatgatgga agagatgatc ttcaaccttg     1320

cagatacaca tctgttcttc aatgacctgg aggattgtga ccagatccac gttgatgacg     1380

tctcatcaga tgacaatggc caagatttaa gcacatacaa cttctccgct gacggcttcc     1440

acagttcggc cccaggagcc aacctgtgcc tgggctctgg cgtgcacggc ggcgtggact     1500

ggatgaggaa gctggccttc cgctaccggc gggtgaagga gatgtacaat acctacaaga     1560

acaacgttgg tgggttgata ggcactccca aaagggagac ctggctacag ctccgagctg     1620

agctggaagc tctcacagac ctctggctga cccactccct gaaggcacta aacctcatca     1680

actcccggcc caactgtgtc aatgtgctgg tcaccaccac tcaactaatt cctgccctgg     1740

ccaaagtcct gctatatggc ctggggtctg tgtttcctat tgagaacatc tacagtgcaa     1800

ccaagacagg gaaggagagc tgcttcgaga ggataatgca gagattcggc agaaaagctg     1860

tctacgtggt gatcggtgat ggtgtggaag aggagcaagg agcgaaaaag cacaacatgc     1920

ctttctggcg gatatcctgc cacgcagacc tggaggcact gaggcacgcc ctggagctgg     1980

agtatttata gcaggatcag cagcatctcc acctgccatc tcaccctcag accccctcgc     2040

cttccccacc tccccaccga gaactccaga gacccagatg ttggacacca ggaaggggcc     2100

ccacagccga gacgacgtgt ccagtgacca tctcagaagc cgtccatcag tccaaatggg     2160

ggttctgaga aggaaagtac ccaacattgg cttcggagta tttgactttg gggaaaaggg     2220

ctggctcgga gtctagactc ttctgtaaga ctcacagaac aaaagcaagg aattgctgat     2280

ttggggggtg cctggtgatg aggaggggat gggtttgtct tgtcttcttt ttaatttatg     2340

gactagtctc attactccgg aattatgctc ttgtacctgt gtggctgggt ttcttagtcg     2400

ttggtttggt ttggtttttt gaactggtat gtggggtggt tcacagttct aatgtaagca     2460

ctctattctc caagttgtgc tttgtgggga caatcattct ttgaacatta gagaggaagg     2520

cagttcaagc tgttgaaaag actattgctt atttttgttt ttaaagacct acttgacgtc     2580

atgtggacag tgcacgtgcc ttacgctaca tcttgttttc taggaagagg gggatgctgg     2640

gaaggaatgg gtgctttgtg atggataaaa ggcattaaat aaaaccacgt ttacattttg     2700

aa                                                                    2702


<210>  1188
<211>  2465
<212>  DNA
<213>  homo sapiens

<400>  1188
ctgagctgag tgacaggaag acggttcaat gggcggcgcg gaggcggagc cgtgggggcg       60

ggctcccggt cccgctatcg gcggccggcg ggcaggcgac tcctgtcccg ggtggaggcg      120

gcggagccgg agccggggga gggggcagcg gctgtctcac ggaccacggc ggcgcccgca      180

gctcctcacc gaaacaagga gaccagtgct ggtccagtgg ctgtgatggg aaaagattat      240

tacaagattc ttgggatccc atcgggggcc aacgaggatg agatcaagaa agcctaccgg      300

aagatggcct tgaagtacca cccagacaag aataaagaac ccaacgctga ggagaagttt      360

aaggagattg cagaggccta tgatgtgcta agtgacccca agaaacgggg cctgtatgac      420

cagtatgggg aggaaggcct gaagaccggc ggtggcacat caggtggctc cagtggctcc      480

tttcactaca cctttcatgg ggacccccat gccacctttg cctccttctt tggtggctcc      540

aaccccttcg atatcttctt tgccagcagc cgctccactc ggcccttcag tggctttgac      600

ccagatgaca tggatgtgga tgaagatgag gacccatttg gcgctttcgg ccgttttggc      660

ttcaatgggc tgagtagggg tccaaggcga gccccagaac cactgtaccc tcggcgcaag      720

gtgcaggacc ccccagtggt gcacgagctg cgggtgtccc tggaggagat ctaccatggc      780

tccaccaagc gcatgaagat cacaaggcgt cgcctcaacc ctgatgggcg aactgtgcgc      840

accgaggaca agatcctgca catagtcatc aagcgtggct ggaaggaagg caccaagatc      900

accttcccca aagaaggcga cgccacacct gacaacatcc ctgctgacat cgtctttgtg      960

ctcaaagaca agccccatgc acacttccgc cgagatggca ccaacgtgct ctacagtgcc     1020

ctgatcagcc tcaaggaggc gctgtgtggc tgcactgtga acattcccac tatcgacggc     1080

cgagtgatcc ctttgccctg caatgatgtc atcaagccag gcaccgtgaa gagactccgt     1140

ggggagggcc ttcccttccc caaagtgcca actcagcgag gagacctcat tgttgagttc     1200

aaagttcgct tcccagacag attaacacca cagacaagac agatccttaa gcagcaccta     1260

ccctgttcct aggctctgcc ccagccagtc cagagcctac cacagcaata cccccaacac     1320

tcactccact caatgtgcac ccagcttgat gtccactgga cactggcaac tttttctaaa     1380

atgcaaaaaa aagccactgg ttttcaggaa aatgttcctg tccctgaccc cttttagagc     1440

tgggctgcct ggggggagtg ggagggaggt ggggagagct agcccaggcc aggggtcaat     1500

gttcatgtca ctagctttca atccagtttc cactgcagtg gctggagagt gacctgagtg     1560

ctacttgaag atatgtagag attccttatc catgcctgta catagcatgt cctcctcccc     1620

tcagctttgc taataccagt cccctccctt ccctttggct tcctgctgtt gggggtggaa     1680

aagactagaa aggacattgc tttctcagcc ccacccccag gtccacagtg tccaaggtaa     1740

tggcacacat attcatgcac aagaagcact cacctagagc tgtctgtgcc tctctgggag     1800

aaaggagaga ggataagaag ggaaagttca caacctgtga acagggactt gagcacgaga     1860

cacttttcat ctggagcagg ggggtgagct cctcagcagc ctccgtaaca gctgccctgc     1920

ctacacctgc agagctggag gttctgtcct ccctgctgct ctcaggagtg ttcaagggtg     1980

gagggcaggg aatggggcct gaggtattaa ggctaagagg tgggggacag ggcccatcta     2040

ccagccttca tcaggaaggg aaagggcttt ggggtcaggt ggcagctatt ccccaccaag     2100

agattcaggg tcacaggttt ttccccacac ctctgaactc agggcctagc cacccccaaa     2160

cttccaaatc ccacttttgt gatatgtgaa gctactcatt tcttaccctt ggaggctgtg     2220

tggggaattt ccagcccttt tatgcctgtg tgatcccacc ccacccccat agttgtataa     2280

aggtcatagt gaagaagctg ggggaagact gcttcagcca gatcctgggg tggggtcttt     2340

aggttttctc actttgacaa cccccgaatg tttttatagt agtttttttg tatttttttg     2400

taatgacagt attatgtaaa aaataaagta ttttaaaaat atggcaaaaa aaaaaaaaaa     2460

aaaaa                                                                 2465


<210>  1189
<211>  3092
<212>  DNA
<213>  homo sapiens

<400>  1189
gccgttaggt ggtggggttt ctcagcccgg cggcgggagg cgggccggcc tcggcttcct       60

gtcggaggac gcgcaaggat ccgggcgtcg gagtgtgtgc gagtgcgtga gtgtgtgtcg      120

gtcgcacggc gtgtgtctcc ggccgcgggt tccgcctcct cccctgccgc cgctgctcac      180

ggtgtaagtc aatgtgaagc agcagctcca gccccgggat aaacatggcg acgtctctgc      240

atgagggacc cacgaaccag ctggatctgc tcatccgggc cgtggaagca tcagttcaca      300

gcagtaatgc acactgtaca gataagacaa ttgaagctgc tgaagccctg cttcatatgg      360

aatctcctac ctgcttgagg gattcaagaa gtcctgtgga agtgtttgtt cctccttgtg      420

tatcaactcc agaattcatc catgctgcta tgaggccaga tgtcattaca gaaactgtag      480

tggaggtgtc aactgaagag tctgaaccca tggatacctc tcctattcca acatcaccag      540

atagccatga accaatgaaa aagaaaaaag ttggccgtaa accaaagacc cagcaatcac      600

caatttccaa tgggtctcct gagttaggta taaagaagaa accaagagaa ggaaaaggaa      660

acacaaccta tttgtgggag tttcttttag atctacttca agataaaaat acttgtccca      720

ggtatattaa atggactcag agagaaaaag gcatattcaa gctggtggat tcaaaggctg      780

tctctaagct ttggggaaag cataagaaca aaccagacat gaactatgaa accatgggac      840

gagctttgag atactactac caaaggggaa ttcttgcaaa ggttgaagga cagaggcttg      900

tatatcagtt caaggatatg ccgaaaaaca tagtggtcat agatgatgac aaaagtgaaa      960

cctgtaatga agatttagca ggaactactg atgaaaaatc attagaacga gtgtcactgt     1020

ctgcagaaag tctcctgaaa gcagcatcct ctgttcgcag tggaaaaaat tcatccccta     1080

taaactgctc cagagcagag aagggtgtag ctagagttgt gaatatcact tcccctgggc     1140

acgatgcttc atccaggtct cctactacca ctgcatctgt gtcagcaaca gcagctccaa     1200

ggacagttcg tgtggcaatg caggtacctg ttgtaatgac atcattgggt cagaaaattt     1260

caactgtggc agttcagtca gttaatgcag gtgcaccatt aataaccagc actagtccaa     1320

caacagcgac ctctccaaag gtagtcattc agacaatccc tactgtgatg ccagcttcta     1380

ctgaaaatgg agacaaaatc accatgcagc ctgccaaaat tattaccatc ccagctacac     1440

agcttgcaca gtgtcaactg cagacaaagt caaatctgac tggatcagga agcattaaca     1500

ttgttggaac cccattggct gtgagagcac ttacccctgt ttcaatagcc catggtacac     1560

ctgtaatgag actatcaatg cctactcagc aggcatctgg ccagactcct cctcgagtta     1620

tcagtgcagt cataaagggg ccagaggtta aatcggaagc agtggcaaaa aagcaagaac     1680

atgatgtgaa aactttgcag ctagtagaag aaaaaccagc agatggaaat aagacagtga     1740

cccacgtagt ggttgtcagt gcgccttcag ctattgccct tcctgtaact atgaaaacag     1800

aaggactagt gacatgtgag aaataaaata gcagctccac catggacttc aggctgttag     1860

tggcagtact gacataaaca tttgcaaggg aagtcatcaa gaaaagtcaa agaagacttt     1920

aaaacatttt taatgcatat acaaaaacaa tcagacttac tggaaataaa ttacctatcc     1980

catgtttcag tgggaaatga actacatatt gagatgctga cagaaaactg cctcttacag     2040

taggaaacaa ctgaacccat caataagaaa aaggatcgaa agggaccaag cagctcacta     2100

cgatatcaag ttacactaag acttggaaca ctaacattct gtaagaggtt atatagtttt     2160

cagtgggagg ggttgggatg ggtaatctca ttgttacata tagcaatttt tgatgcattt     2220

tatatgcata ccagcaatta ttactgtgtt cgcacagttc tcacttaact ggtgctatgt     2280

gaagactctg ctaatatagg tattttagaa tgtgaattga agaatggatc ccaaaaactt     2340

cagaaagagg atagcaaaaa aagatctagt gcgattttat atatatatat atatatatat     2400

acatacatat atatatatca tatagcttaa gctgatttaa aacaaaggcc ttagactaat     2460

tttcgatttt ctttcttgaa ataagctaat ggcttgtttg tgtaaagctt ttttattaaa     2520

agaaaaattt taaaaatctt gtacctagca cagtattgtt atagaatata catgtaacat     2580

tttatatggt agtttaagtc tgtcagtttc ttaattgtgg acaaattaac agttggctct     2640

ggccttttgc tgtaacatgc ctgtgtcact cacttagcct tggcatttgt gcagacatac     2700

cattttcagt tctgctgtca cttggaagtt caggctcagc atgaattttt ggcaggtagc     2760

tctaatacct ggagttttct ttgttttttt ttcttttttt tagttgaagt ttatgaggga     2820

aataccagtg ttcagttttg aactataata gtttgtatat tcaacatttg aagtatattc     2880

tattttgttg tactcttgtt tcaaagtgta ttcaagtagg ttttctgaaa tatagaaatg     2940

aaatttatct tctgttttgg tctctggtga tattttaaac aatatttaaa agtcagtata     3000

gaagtgtttt agttaggaag tgataaaaca tctctcttct ccttcccaac tactgcatga     3060

agaaattcta cttccattat attaatattt gg                                   3092


<210>  1190
<211>  3263
<212>  DNA
<213>  homo sapiens

<400>  1190
ctgagctcag ggaggagctc cctccaggct ctatttagag ccgggtaggg gagcgcagcg       60

gccagatacc tcagcgctac ctggcggaac tggatttctc tcccgcctgc cggcctgcct      120

gccacagccg gactccgcca ctccggtagg attccccgcc tgtcattccc tagcccagct      180

cttgggaaac tgcagagggg tccagaggat ttgcagttct gaacctgcac actccagtct      240

aggatctccg agcaagagcg tagcctcatg gctgcaacct gtgagattag caacattttt      300

agcaactact tcagtgcgat gtacagctcg gaggactcca ccctggcctc tgttccccct      360

gctgccacct ttggggccga tgacttggta ctgaccctga gcaaccccca gatgtcattg      420

gagggtacag agaaggccag ctggttgggg gaacagcccc agttctggtc gaagacgcag      480

gttctggact ggatcagcta ccaagtggag aagaacaagt acgacgcaag cgccattgac      540

ttctcacgat gtgacatgga tggcgccacc ctctgcaatt gtgcccttga ggagctgcgt      600

ctggtctttg ggcctctggg ggaccaactc catgcccagc tgcgagacct cacttccagc      660

tcttctgatg agctcagttg gatcattgag ctgctggaga aggatggcat ggccttccag      720

gaggccctag acccagggcc ctttgaccag ggcagcccct ttgcccagga gctgctggac      780

gacggtcagc aagccagccc ctaccacccc ggcagctgtg gcgcaggagc cccctcccct      840

ggcagctctg acgtctccac cgcagggact ggtgcttctc ggagctccca ctcctcagac      900

tccggtggaa gtgacgtgga cctggatccc actgatggca agctcttccc cagcgatggt      960

tttcgtgact gcaagaaggg ggatcccaag cacgggaagc ggaaacgagg ccggccccga     1020

aagctgagca aagagtactg ggactgtctc gagggcaaga agagcaagca cgcgcccaga     1080

ggcacccacc tgtgggagtt catccgggac atcctcatcc acccggagct caacgagggc     1140

ctcatgaagt gggagaatcg gcatgaaggc gtcttcaagt tcctgcgctc cgaggctgtg     1200

gcccaactat ggggccaaaa gaaaaagaac agcaacatga cctacgagaa gctgagccgg     1260

gccatgaggt actactacaa acgggagatc ctggaacggg tggatggccg gcgactcgtc     1320

tacaagtttg gcaaaaactc aagcggctgg aaggaggaag aggttctcca gagtcggaac     1380

tgagggttgg aactataccc gggaccaaac tcacggacca ctcgaggcct gcaaaccttc     1440

ctgggaggac aggcaggcca gatggcccct ccactgggga atgctcccag ctgtgctgtg     1500

gagagaagct gatgttttgg tgtattgtca gccatcgtcc tgggactcgg agactatggc     1560

ctcgcctccc caccctcctc ttggaattac aagccctggg gtttgaagct gactttatag     1620

ctgcaagtgt atctcctttt atctggtgcc tcctcaaacc cagtctcaga cactaaatgc     1680

agacaacacc ttcctcctgc agacacctgg actgagccaa ggaggcctgg ggaggcccta     1740

ggggagcacc gtgatggaga ggacagagca ggggctccag caccttcttt ctggactggc     1800

gttcacctcc ctgctcagtg cttgggctcc acgggcaggg gtcagagcac tccctaattt     1860

atgtgctata taaatatgtc agatgtacat agagatctat tttttctaaa acattcccct     1920

ccccactcct ctcccacaga gtgctggact gttccaggcc ctccagtggg ctgatgctgg     1980

gacccttagg atggggctcc cagctccttt ctcctgtgaa tggaggcaga gacctccaat     2040

aaagtgcctt ctgggctttt tctaaccttt gtcttagcta cctgtgtact gaaatttggg     2100

cctttggatc gaatatggtc aagaggttgg aggggaggaa aatgaaggtc taccaggctg     2160

agggtgaggg caaaggctga cgaagagggg agttacagat ttcctgtagc aggtgtgggc     2220

ttacagacac atggactggg ctgggaggcg agcaaaggaa gcagctgaga ctgttggaga     2280

acgcttacaa gacttcatgc aagcaaggac atgaactcag aacactgagg tcagaagcat     2340

cctgctgtca tgacaccgct cgagtgacct tgaccttgac caagtctgtc ctgtttagga     2400

ctgatttttc ctattaggct agggtttgga cctgatgttc tcaagatgtc tagaattgca     2460

tggctggcct tgtggaatag atggttttgc attccagcca agtgtgctgt aaactgtata     2520

tctgtaatat gaatcccagc ttttgagtct gacaaaatca gagttaggat cttgtaaagg     2580

aaaaaaaaaa aaaaacaaaa caaaatggag atgagtactt gctgagaaag aatgagggaa     2640

ggagttggca tttgttgaaa gtgtagtctt tttctctttt ttttttaatt gcaactttta     2700

ctttagattt aggaggtcgt gcgcaggttt gttacatggg tatattgtgt gatgctgagc     2760

ttgggatgcg aatgatcctg tcacccaggt agtgagtata gcacccagtg aaactgtagt     2820

ctcatgccag gcactgtgct agcccactct ggctcattta atcctctcct aagaagagag     2880

gagacacagc gtccccattt gacagatgca gaaagaggtt ccacaggtgt gccttgattc     2940

tgtcctaaaa ccgtttcccg gaagcttttc ctggtgtggg cgcttctaac ctaatcctca     3000

atcgattcca gaactattac tctgtttcca cagtgatact gtgtctaggt tttagggagg     3060

acagttcatt gatgttactt aagaatgctt tccaggtgga aagttcctta agtttgaggc     3120

ttcaaattcc atacagcaca ttaaaatccc attcatgagt ttgaaatact gctctgttgt     3180

cttggaaata ccaatcagat tgttggctga agtgatgtgg ataaagaagg gatcttagaa     3240

aaactaaaaa aaaaaaaaaa aaa                                             3263


<210>  1191
<211>  2990
<212>  DNA
<213>  homo sapiens

<400>  1191
aactacaaaa ttgaaagtag agaggagggg gcagccaatg gaaaaaaaaa tttgcacagc       60

agccaatcct cctgcggcgt tttgtgcctt tgcccaacag gaaaatgtgt ctcatgcaga      120

ggggcgttac ccagtctcca atgggcggga gccggtggaa cggaggagcc aatgagtgcg      180

agatgttgag tgacagctgt ccaatggagg ccctccgtgc tagtacggct tgcggcttaa      240

gcgccgccgc ggtctgcgga atgtcaacta ttcaacatgg aggcggaggt cgataagctg      300

gaactgatgt tccagaaagc tgagtctgat ctggattaca ttcaatacag gctggaatat      360

gaaatcaaga ctaatcatcc tgattcagca agtgagaaaa atccagttac actcttaaag      420

gaattgtcag tgataaagtc tcgatatcaa actttgtatg cccgctttaa accagttgct      480

gttgagcaga aagagagtaa gagccgcatt tgtgctactg tgaaaaagac tatgaatatg      540

atacaaaaac tacagaagca aacagacctg gagctgtcac cactgactaa agaagagaaa      600

actgcggcag agcaattcaa atttcacatg ccagatttat gaagaaatgg acttggaaag      660

gaaattctaa cagagaagag cttaattccg gagaaattta ggaagatgtc ttgttaaccc      720

ttgatgtcta gagattgggg gctggtgaag ggggtttggc ttcaatgact ggataatgat      780

atctttcatg agagagatta taagaagaag ggcagataat atatgaataa agttcagcca      840

aaaggatcaa atgagaataa aacgatttaa atatatgtac acacgcatgc acacacacac      900

ttagtcttgt aatttcaggc cagaaattct caacactatt ttgcatctgt tttctttttc      960

taagtcatga taatatagat gttctggtct atcataaaag aatgtttatg tacatttcag     1020

tcattcggta tgtggctttg taaattaaag tataggcaaa acatttgtgt tatacatgat     1080

atataatttc attttgtaaa tgttgattgc acatgtggtc acattattgt tgagactgct     1140

tttatgtgac ctgtagtctc ccacagaacc taaagtaata agctggcttt tctgtgatag     1200

ccacgtttgc gtatttcttt ccctatttcc cttgcctgct aatgttgaac agcatgaact     1260

tgctttctga tgctgtttta gactgtccct gttgtatctc aataatatct ttgttttcct     1320

tcagccttta ttactataat tgttcattct acatgaaagc taggaaactg aaattagaag     1380

agcacttatc tgctacttgc cagttttgcg tgagtgtgtt atatgtatgt gtcaatttcc     1440

ctttaaaata actatttatt ttaaaataac tattggcaat aaggaaactg ttcaaagtag     1500

aggcagatct tgatagaaag atgttaatca cagggttgtt tataatagca atatacatac     1560

acatttggct agtactaggt gaataggaaa ataaatcatg ctgtatgtat acaataagag     1620

gtcaagttgc caataaatta ttactgttaa tgttctggga aatgctgaaa ctatgctaag     1680

tgggggagag ggaaagcagg tattgcagtt ttgtagtgaa gattgggctt tggagtcata     1740

tctgagatgt aagtagcagc ttttaaattc tagctatgac cctgtgcaga tcacttaact     1800

tttgagtgtc aggatgtttg gaaggacaag acaggaaagt gttttaatac agggttcagt     1860

atttagtaag ccttcaataa gtgatattac atacatgtaa taaaaactaa gcattgaaag     1920

gactaggaaa aatgcatcaa atgttagttc tgcaggttat agaattatac ttttatgtaa     1980

ttttaaaatt tcagttatga acatgtttgt ccattaacaa acttataata gctgaaaaac     2040

agggttgtga gaacagcttc agttaaaatt gtcctgtcta gtttgaatat ttcaagaaca     2100

gaaagccttt tttttttttt tttttttttt gagacggagt ctcactctgt tgcccaggct     2160

ggaatgcagt ggtacgctct cagctcactg caacctccac ctcccaggtt caagcagttc     2220

tctgccccac cctcccgagt agctgggatt acaggcgccc gccaccacgc ccggctattt     2280

ttttgtattt ttagtagaga tggggcttca ccatcttgac caggctggtc tttaactcct     2340

gatggtgatc cacccacctc ggcctcccaa agtgctggga ttacaggcat gagctaccgt     2400

gcctggcccc ctttttttta attacagaga aataagttac accttagtat cagatattaa     2460

ttttcttcag tgttcaggca attagtattt agaaagctct tgtcatgaga tggctctggg     2520

atgtgatgat gattgttggg attgaaaaaa cggtagtatc atggagagat cataataaat     2580

tcttagtatt aaaagtggtt ttgctttcag ttagggagaa aaattagatt gtactatttt     2640

tcctctatga tttccttcag ttatcttcca aatgttgttt tttccccaca gcccccttaa     2700

cattgttctc tatgcacttc tcaatacatt ttcatttgtt tctcaagcct ctttgtggat     2760

gactcctaaa tataacttct tccactagct ctagatccgt atttccaata aaatccccta     2820

cctgaatatt caagttaaac atgtccagaa tacttactga ttttattgtt aatagccact     2880

attctgttgt ctggaattaa aacctgtata actaatttgc atccctttat cttcttagtc     2940

aataaaacct acaatcctct ttctaaaatg gtaaaaaaaa aaaaaaaaaa                2990


<210>  1192
<211>  2838
<212>  DNA
<213>  homo sapiens

<400>  1192
gggcgcagag ctgggccgag ccgtcgccgg cgccacgcga gtcccgcagc cgccgcgccc       60

gggcaatggg ccgggggcac tgagggccgc cggggccgag cgcggagggg ggaccgagcc      120

agtgccgtgc cctcgggccg cgccaacatg ccccgcggct tcctggtgaa gcgcagcaag      180

aagtccacgc ccgtttccta ccgggtccgc ggcggcgagg acggcgaccg cgcactgctg      240

ctctcgccca gctgcggggg cgcccgcgcc gagcccccgg cgccgagccc ggtccccggg      300

ccgctgccgc cgccgccgcc cgcggagcgc gcccatgcag cgctcgccgc cgcgcttgcc      360

tgcgcgcctg ggccgcagcc acccccgcag ggcccgcggg ccgcgcactt cggcaacccc      420

gaggctgcgc accccgcgcc gctctacagt cccacgcggc ccgtgagccg cgagcacgag      480

aagcacaagt acttcgaacg cagcttcaac ctgggctcgc cggtctcggc cgagtccttc      540

cccacgcccg ccgcgctgct cggagggggc ggcggcggcg gcgcgagcgg agctggcgga      600

ggcggcacct gcggcggcga cccgctgctc ttcgcgcccg ccgagctcaa gatgggcacg      660

gcgttctcgg ctggcgccga ggcggcccgc ggcccgggcc ccggcccccc actgccccct      720

gccgccgccc tgcggccccc gggaaagcgg cccccgcccc ctaccgccgc ggagccgccc      780

gccaaggcag tcaaggcccc gggcgccaag aagcccaagg ccatccgcaa gctgcacttc      840

gaggacgagg tgaccacgtc gcccgtgctg gggctcaaga tcaaggaggg cccggtggag      900

gcgccgcggg gccgcgcggg gggcgcggcg cggccgctgg gcgagttcat ctgccagctg      960

tgcaaggagg agtacgccga cccgttcgcg ctggcgcagc acaaatgctc gcgcatcgtg     1020

cgtgtggagt accgctgtcc cgagtgcgcc aaggtcttca gctgcccggc caacctggcc     1080

tcgcaccgcc gctggcacaa accgcggccc gcgcccgccg ccgcccgcgc gccggagcca     1140

gaagcagcag ccagggctga ggcgcgggag gcacccggcg gcggcagcga ccgggacacg     1200

ccgagccccg gcggcgtgtc cgagtcgggc tccgaggacg ggctctacga gtgccatcac     1260

tgcgccaaga agttccgccg ccaggcctac ctacgcaagc acctgctggc gcaccaccag     1320

gcgctgcagg ccaagggcgc gccgctagcg cccccggccg aggacctact ggccttgtac     1380

cccgggcccg acgagaaggc gccccaggag gcggccggcg acggcgaggg ggccggcgtg     1440

ctgggcctga gtgcgtccgc cgagtgccac ctgtgcccag tgtgcggaga gtcgttcgcc     1500

agcaagggcg ctcaggagcg ccacctgcgc ctgctgcacg ccgcccaggt gttcccctgc     1560

aagtactgcc cggccacctt ctacagctcg cccggcctta cgcggcacat caacaagtgc     1620

cacccatccg aaaacagaca ggtgatcctc ctgcaggtgc ccgtgcgccc ggcctgctag     1680

agcgcgccct ccaccccggc ccccgaactg tgccttcgct tggagaccca caaagagagt     1740

gcgccctgca cgccccgaac ccgagtccgc gctgggggag cctcgccccc gcccccaccg     1800

ggtgaaagtg tcgtctccgc ttctctcggt gtggcgtgac ggtaacccca tactctcctt     1860

ttgactcctt ttggaacccc cacttttacg ttgtgtccct ccgcctcccc catggcgcaa     1920

caggagtcag tctctttctg tacaagggag aaaagctgta cgcgtttgtc tcgtggttgg     1980

aagcctcccc ttggcgggga gaagcttttt ttcttgctag tattcgctgt gttcatggtc     2040

tagaaatgcg gtctggtctc gcctcgccta ccaatctctg ctctctatgt atgtagcgta     2100

cgggttgttt tgggtgaatc ttgaggaata aatgccttta tatttcacag gctgtaaatt     2160

gaacttccca cacgattagc tttattatgg cttgtgaact gctggagtct ggctttacct     2220

ttttgtatgt gaacaaatca aattgcttaa aaaagagttt tctttagtat agccacaaat     2280

gccttgaact gttgtctggg attgttttgt ggggggaggg aagggagtgt tccgaagatg     2340

ctgtagtaac tgcctcagtg tttcacgtaa gactttttgg tttgatcatc tttgttgagg     2400

taggactatc agttccctct aaatgtatat gttgatttat gagtaattgt tatttattct     2460

ttatttattt atattaatta tgaagattat gatattattt gattgcagat ttttttggcg     2520

cgctgccccc tccccaccct gccactcttg acattccact gtgcgtttta gaagagagcc     2580

tttttctaaa gggatctgct taaagtttta acttttatac ctatctgagt gaattacaga     2640

caacctatca tttattctgc ttcgagggtc cccagggccc ttgtacaacc gacagctctt     2700

acttttaaat gcaatctctt ttctacatac attattttct taattgttag ctatttatag     2760

aaagcttcaa tagaactgtt tcaactgtat aactatttac tattcaaata aaatattttc     2820

aaagtcaaaa aaaaaaaa                                                   2838


<210>  1193
<211>  6019
<212>  DNA
<213>  homo sapiens

<400>  1193
gacctcccac aactggagca gccgggaaca gctctgacca cagtggttcc ggggagaagc       60

ctttccagga cccatgtgta ggcacaactg ttttccctga tcaggatact tgcggcactc      120

aacagaggaa agaaattcct aagggaacac tgctcagaaa gtactgcagc atgtcttcaa      180

atgcctgagg atcaagttgg aaaactagaa gcaacagaaa acacaataag cgcaatggcg      240

gcggccgcgg cggagcagca acagttctac ctgctcctgg gaaacctgct cagccccgac      300

aatgtggtcc ggaaacaggc agaggaaacc tatgagaata tcccaggcca gtcaaagatc      360

acattcctct tacaagccat cagaaataca acagctgctg aagaggctag acaaatggcc      420

gccgttctcc taagacgtct cttgtcctct gcatttgatg aagtctatcc agcacttccc      480

tctgatgttc agactgccat caagagtgag ctactcatga ttattcagat ggaaacacaa      540

tctagcatga ggaaaaaagt ttgtgatatt gcggcagaac tggccaggaa tttaatagat      600

gaggatggca ataaccagtg gcccgaaggt ttgaagttcc tttttgattc agtcagctct      660

caaaatgtgg gactgcggga agctgccctt cacattttct ggaactttcc tggaattttt      720

gggaaccagc aacaacacta tttagatgtc atcaaacgaa tgttagttca gtgtatgcaa      780

gatcaggaac acccgtcgat caggacgtta tctgctagag ctacagctgc atttatactt      840

gcaaatgagc ataatgttgc tctgttcaaa cattttgcag acttgctacc gggattccta      900

caggcggtaa atgactcgtg ctaccagaat gatgattctg tcctaaaatc cctcgttgag      960

attgcagata ctgttccaaa gtatttgcgt cctcacttgg aagcaactct acagctaagt     1020

ctaaagttgt gtggagacac tagcctcaac aatatgcaac gccagcttgc ccttgaagtg     1080

atcgtcaccc tctctgagac tgcagctgct atgttaagaa aacataccaa tattgttgca     1140

cagactattc ctcagatgtt agcaatgatg gttgatttgg aagaagatga ggactgggca     1200

aatgcagatg aactagaaga tgatgatttt gacagcaatg cagttgcagg cgagagtgct     1260

ctagatcgaa tggcttgcgg acttggtgga aagctcgttc tgccgatgat caaggaacac     1320

attatgcaaa tgcttcaaaa tcctgactgg aaataccggc atgcaggatt gatggcctta     1380

tctgccattg gtgaagggtg ccaccagcaa atggaaggaa ttctaaatga gatcgtaaat     1440

tttgttttac tttttctcca ggatcctcat ccaagagtaa ggtatgcagc ctgtaatgcc     1500

gtgggacaga tggctacaga ttttgcacct ggtttccaaa agaaatttca tgagaaggtg     1560

attgcagctc tgctgcagac catggaagac caaggcaatc aacgtgtgca ggcccatgca     1620

gctgctgccc tcattaactt tactgaagac tgtcccaagt cactacttat tccatacttg     1680

gataatttgg tgaaacatct gcattccatt atggtactga agcttcaaga gctgattcag     1740

aaaggcacca agttagtttt ggaacaagtt gtgacatcca ttgcatcagt tgccgatact     1800

gcagaagaaa aatttgtccc ctactatgat ttatttatgc catcactgaa gcacatcgtt     1860

gagaatgcgg ttcaaaaaga actgagactt ctgagaggaa aaactattga atgcattagc     1920

ctcattggtc tggctgttgg gaaggaaaaa ttcatgcagg atgcatcaga tgtgatgcag     1980

cttttgttaa agacccagac agacttcaat gatatggaag atgatgatcc tcagatctct     2040

tacatgatct cagcatgggc cagaatgtgc aaaatccttg gaaaagaatt tcagcaatac     2100

cttccagtgg ttatggggcc tttaatgaag acggcttcaa ttaagcccga agtagccctt     2160

ttagataccc aagacatgga gaatatgagt gatgatgatg gttgggaatt tgtgaacctt     2220

ggagatcagc aaagctttgg tattaaaact gcaggactag aagaaaaatc aactgcttgc     2280

cagatgttgg tttgctatgc taaggagtta aaggaaggct ttgtggagta caccgaacag     2340

gttgtcaaac tgatggtccc tttactgaaa ttttatttcc acgatggtgt tcgagtggca     2400

gcagcggaat ccatgcctct tctcctggag tgtgcaagag tccgtggtcc tgagtatctc     2460

acacagatgt ggcattttat gtgtgatgct ctaattaagg ccattggtac agaaccagat     2520

tcagacgtcc tctcagaaat aatgcattct tttgcaaagt gcattgaagt aatgggagat     2580

ggatgcctta ataatgaaca ctttgaagaa ctgggaggta tattgaaagc aaagcttgaa     2640

gaacatttta aaaatcaaga attacgacaa gttaaaagac aagatgaaga ctatgatgaa     2700

caggtcgaag agtcactaca agatgaggat gataatgatg tttatattct gaccaaagtg     2760

tcagatattt tacactcaat attcagtagc tacaaagaaa aggtgttacc atggtttgaa     2820

cagctgcttc cattaattgt caacctcatt tgtccacata gaccatggcc agacagacaa     2880

tggggattat gcatctttga tgatgtcata gaacactgta gtccagcctc atttaaatac     2940

gcagaatatt tcttaagacc aatgctccaa tatgtatgtg acaacagccc agaagtcagg     3000

caagcagctg catatggcct gggagtcatg gcacagtacg gtggagataa ttatcgccct     3060

ttttgtacag aagcacttcc cctgctggta agagttattc agtctgcgga ttctaagacc     3120

aaagaaaatg tcaatgctac agagaactgc atctcagcag tagggaaaat catgaagttc     3180

aagcctgact gtgtaaacgt tgaagaggtc cttccacact ggttgtcttg gcttccacta     3240

catgaagata aagaagaagc tgttcagact ttcaattatc tgtgtgacct gattgaaagt     3300

aatcatccaa ttgttcttgg cccaaacaat accaatctgc ccaaaatatt tagtataatt     3360

gcggaaggag aaatgcacga ggcaattaaa catgaagatc cttgtgccaa acgtctggcc     3420

aatgtcgttc gccaagtaca gacttctgga ggactgtgga ctgagtgcat agcacagctc     3480

agtcctgagc agcaggccgc cattcaggag ctcctgaact ctgcgtgaag ggccttaatg     3540

tcacccacca gaaaactaac tccaaataaa cgcttaccct ttcctttagg tttctttgtt     3600

ttgtttttga gcaaaagaga tcggtagtgt tgtgtgtagg ccattcttct ggagagccac     3660

aagcaggaag agcagcgctg tgttgcagaa tggagtttcc atggatttct accagaccac     3720

tgaaggagtt cctggaagcc ctgcggtagc tagcactgaa gactattttt ctattggtat     3780

aacccgccca cctgaagggg aaagggaaat caaattaatt tttctcgtta gacataagga     3840

aatttaagga aaaacagctt taagaacagt tactcagcgt agatgtgtgt tcacacaaat     3900

tgctctgcat tcagtgttca ttgtgaattg ggagtgtgag tctttctgta gggtagaaag     3960

aagcctccta cccagcaaac cagtagaccc aaaagttgaa aaaaactgat gacagacaac     4020

aagcatgaag atggcatatt tgatgtcact ttggttcttt ttcccagaag gcttatacag     4080

tgactcagtc gggaagcttt ccagcttcca gcccttgaat gtgaagtgtc attggcatgt     4140

ctggcagtag tctctcattc actcctcaat aaacaacatt gaatacaaaa gaggcttgtg     4200

taaaaactca gtactgtctg gcttggattc atttcatgtt tttaatataa gaatgatcta     4260

atattttttt aaagtaatag ctatcagtaa tagctgagtg ttttttcccc taatattttc     4320

cttgtgcaat tcagacttaa gcatcgagtt tttaccatct tccactttaa gctaagttat     4380

gatacctatt ccattcacaa ttggtgttct ttttaaggtt tgcaaatttc agccaatttt     4440

gtagctaaga ttgttctgat cagctcaaaa agatttggct tagtgttttc attgcaaatt     4500

ataattgctg tagagccaca cacaactttt gaacttttaa ttataagtgt tatggctaaa     4560

gttatttact gaaaatttca gtaaaatgtg tgaatgtttc tttatgtatt aacctcatag     4620

cagtaaatga cttgctgttg tttaattttt ctaaggcatc ttaatagact tctgttgaaa     4680

acttcagtgt taacattttt atagtttgta ctaaatttaa ccgtgatata aaaatgaatt     4740

ttatgcatag atcagaattt taaattaaag gttttttctt taaatgattt gtattacttt     4800

attaaaacta aatctgaaat ggaatagaaa atagaatgga ttacatacag atggtttcct     4860

tgttagcaga tgcccttcaa atatatttta cgtttgcagc acaacaccat tgcccggagg     4920

cttccgaatc tagcaaagca gcatattaaa tgactccacc tgcgcagtcc ttgtgttcag     4980

tggatgaata cctgtgggct cttgtaatgt gtggtaatat ttggagcttt atagcctgta     5040

ttccttggga gaaaaaaatg ggaattggag taaaaagtgt gtcaagacaa cccctttctg     5100

ctttcttatg tagcatctgc aaagccgatt catgtactga tgccaatcag ctagagcaat     5160

gtaggctttt tttaatttaa attattacta cactttatta ctacacttgc agaaaagaaa     5220

catgttaaaa tcatggcaca cctgcagaat ttcagatgac agtgtggtca gaagatgttt     5280

tttgggagaa cctagtgttt gctgggcact atgctaagca ctttgggagc aagaacctcc     5340

taccttccag tttaaacact agtggtattg tcagatgccg ttagtatctg agatgtactt     5400

acagcagggt tctaagagct ctgaaagaag cgctctgtta gatgcagact ggcagcatcc     5460

tccttgataa aagcagaaaa gcaaagaggt aattggagtt gaatcaagtt aatagggaag     5520

gttggtagta aatgctgtta gtgtgacatg attctgaaac ccagagctca gaactaactg     5580

tgagatgtac catgaactaa caattctttg aaaggacctg cagaagcatt tttaatacct     5640

cattctgtct atgcaagatg aaaatccatg gagttttttc ttggcttttg taccaaattt     5700

aggggtcttg catgtcagca agtgatatat attgtttata aatgcaagct atttctggag     5760

gggaaaaatg tgtgtggctc ttacgttttc tgggaatttt gtaacaagtt acacgcacaa     5820

gtgttagaaa ctttggcata actcaatttg gagtattttt taaatgctgt atctttaaag     5880

aaaagtaaaa ttgtcttaaa tctaattgac acttctgtaa tgagaggcaa ccttataact     5940

ctggagttgt agtttgacag aaccatcagt aaagacataa gcaaataaat ggtcttggtg     6000

caaaaaaaaa aaaaaaaaa                                                  6019


<210>  1194
<211>  2302
<212>  DNA
<213>  homo sapiens

<400>  1194
agccgcggct cttcgcagtt tcctctcctt gttttgcttt cgatctggac tgttctcagg       60

caagccgggg agtaactttt agttttgctc ctgcgattat tcaactgacg ggctttcatt      120

tccatttcac ataccctagc aacacttata ccttgcggaa ttgtattggt agcgtgaaaa      180

aagcacactg agagggcacc atgccggtgg aaaggatgcg catgcgcccg tggctggagg      240

agcagataaa ctccaacacg atcccggggc tcaagtggct taacaaggaa aagaagattt      300

ttcagatccc ctggatgcat gcggctagac atgggtggga tgtggaaaaa gatgcaccac      360

tctttagaaa ctgggcaatc catacaggaa agcatcaacc aggagtagat aaacctgatc      420

ccaaaacatg gaaggcgaat ttcagatgcg ccatgaattc cttgcctgat attgaagaag      480

tcaaggataa aagcataaag aaaggaaata atgccttcag ggtctaccga atgctgcccc      540

tatcagaacg gccttctaag aaaggaaaga aaccaaagac agaaaaagaa gacaaagtta      600

agcacatcaa gcaagaacca gttgagtcat ctctggggct tagtaatgga gtaagtgatc      660

tttctcctga gtatgcggtc ctgacttcaa ctataaaaaa tgaagtggat agtacggtga      720

acatcatagt tgtaggacag tcccatctgg acagcaacat tgagaatcaa gagattgtca      780

ccaatccgcc agacatttgc caagttgtag aggtgaccac tgagagcgac gagcagccgg      840

tcagcatgag cgagctctac cctctgcaga tctcccccgt gtcttcctat gcagaaagcg      900

aaacgactga tagtgtgccc agcgatgaag agagtgccga ggggcggcca cactggcgga      960

agaggaatat tgaaggcaaa cagtacctca gcaacatggg gactcgaggc tcctacctgc     1020

tgcccggcat ggcgtccttc gtcacttcca acaaaccgga cctccaggtc accatcaaag     1080

aggagagcaa tccggtgcct tacaacagct cctggccccc ttttcaagac ctcccccttt     1140

cttcctccat gaccccagca tccagcagca gtcggccaga ccgggagacc cgggccagcg     1200

tcatcaagaa aacatcggat atcacccagg cccgcgtcaa gagctgttaa gcctctgact     1260

ctccgcggtg gttgttgggg cttcttggct ttgttttgtt gtttgtttgt attttatttt     1320

tttctctctg acacctattt tagacaaatc taagggaaaa agccttgaca atagaacatt     1380

gattgctgtg tccaactcca gtactggagc ttctctttaa ctcaggactc cagcccattg     1440

gtagacgtgt gtttctagag cctgctggat ctcccagggc tactcactca agttcaagga     1500

ccaacaaggg cagtggaggt gctgcattgc ctgcggtcaa ggccagcaag gtggagtgga     1560

tgcctcagaa cggacgagat aatgtgaact agctggaatt ttttattctt gtgaatatgt     1620

acataggcag cactagcgac attgcagtct gcttctgcac cttatcttaa agcacttaca     1680

gataggcctt cttgtgatct tgctctatct cacagcacac tcagcacccc cttctctgcc     1740

cattccccag cctctcttcc tatcccatcc catcccatcc catcccatcc catcccatcc     1800

cgctcttttc ctacttttcc ttccctcaaa gcttccattc cacatccgga ggagaagaag     1860

gaaatgaatt tctctacaga tgtcccattt tcagactgct ttaaaaaaaa tccttctaat     1920

ctgctatgct tgaatgccac gcggtacaaa ggaaaaagta tcatggaaat attatgcaaa     1980

ttcccagatt tgaagacaaa aatactctaa ttctaaccag agcaagcttt tttatttttt     2040

atacagggga atattttatt caaggtaaaa ttctaaataa aatataattg ttttttatct     2100

tttctacagc aaatttataa ttttaagatt ccttttcttg tttatcagca gttgttatta     2160

catccttgtg gcacattttt ttttttaatt ttgtaaaggt gaaaaaagct tttatgagct     2220

catgtagcaa tcagattttc ctgtggattg ataataaatg aatatgatat atagttaaat     2280

ttttaaaaaa aaaaaaaaaa aa                                              2302


<210>  1195
<211>  3647
<212>  DNA
<213>  homo sapiens

<400>  1195
gcagttccgc aatcccggcc gctccgggaa gtcgcgcatg cgtagtctcg gccccgggct       60

gccgcgccag cccgtctccg cggcggggga ccgggctgcc ttggcccctc agcgctcgcg      120

tcttttccgg cagttggaac gcttcctgtt gtcctcaccc gtaaccgcct gttgccccct      180

gtctcagagt ccctcacgcg tcccctcccg tctttggctc gttggctgcc gccgccgggg      240

cttcgccagc cttcaagtcg agactactgg ccgaaggggc gtctgcggct ctccgccgtc      300

cccagccctg cctctccctg ggctctgcag ccatggcaat gacaggctca acaccttgct      360

catccatgag taaccacaca aaggaaaggg tgacaatgac caaagtgaca ctggagaatt      420

tttatagcaa ccttatcgct caacatgaag aacgagaaat gagacaaaag aagttagaaa      480

aggtgatgga agaagaaggc ctaaaagatg aggagaaacg actccggaga tcagcacatg      540

ctcggaagga aacagagttt cttcgtttga agagaacaag acttggattg gaagattttg      600

agtccttaaa agtaataggc agaggagcat ttggtgaggt acggcttgtt cagaagaaag      660

atacgggaca tgtgtatgca atgaaaatac tccgtaaagc agatatgctt gaaaaagagc      720

aggttggcca cattcgtgcg gagcgtgaca ttctagtgga ggcagacagt ttgtgggttg      780

tgaaaatgtt ctatagtttt caggataagc taaacctcta cctaatcatg gagttcctgc      840

ctggagggga catgatgacc ttgttgatga aaaaagacac tctgacagaa gaggagactc      900

agttttatat agcagaaaca gtattagcca tagactctat tcaccaactt ggattcatcc      960

acagagacat caaaccagac aaccttcttt tggacagcaa gggccatgtg aaactttctg     1020

actttggtct ttgcacagga ctgaaaaaag cacataggac agaattttat aggaatctga     1080

accacagcct ccccagtgat ttcactttcc agaacatgaa ttccaaaagg aaagcagaaa     1140

cctggaaaag aaatagacgt cagctagcct tctccacagt aggcactcct gactacattg     1200

ctcctgaggt gttcatgcag accgggtaca acaagctctg tgattggtgg tcgcttgggg     1260

tgatcatgta tgagatgctc atcggctacc cacctttctg ttctgagacc cctcaagaga     1320

catataagaa ggtgatgaac tggaaagaaa ctttgacttt tcctccagaa gttcccatct     1380

ctgagaaagc caaggatcta attttgaggt tctgctgtga atgggaacat agaattggag     1440

ctcctggagt tgaggaaata aaaagtaact ctttttttga aggcgttgac tgggaacata     1500

tcagagagag acctgctgca atatctattg aaatcaaaag cattgatgat acctcaaact     1560

tcgatgagtt tccagaatct gatattctta agccaacagt ggccacaagt aatcatcctg     1620

agactgacta caagaacaaa gactgggtct tcatcaatta cacgtacaag cgctttgagg     1680

gcctgactgc aaggggggca ataccttcct acatgaaagc agcaaaatag tactcttgcc     1740

acggaatcct atgtggagca gagttctttg tataacatca tgcttttcct ctcacactct     1800

tgaagagctt ccaagaagtt gatggaaccc accaatatgt catagtaaag tctcctgaaa     1860

tgtggtagta agaggatttt cttccataat gcatctgaaa aactgtaaac aaagacaacc     1920

atttctacta cgtcggccat aaacagctat cctgctttgg aagagaagca tcatgagcca     1980

atttgatagg tgttttaaaa ataacttgag ttttcctaag ttcatcagaa tgaaggggaa     2040

aaacagccat catccaacat tattgagatt gtcgtgtata gtcatcgaat atcagccagt     2100

tcctgtaatt ttgtgacacg ctctctgcca agcccaccaa gtatttcctt tatagctaaa     2160

agttccatag tactaaggaa ataaagcaat aaagacagtc tcagcagcca ggattctggc     2220

tgaaggaaat gatccgccac cctgagggtg gtgatggtag tttctaccca tacctcagcc     2280

tcaggcgagt ggcttatagc ctccattcat ggtgcacttt atttatggta ctaagataaa     2340

gactgtcaat ccattgattt atctcctcct gtcccccatc taaaataccc atgctgcttt     2400

tctgagtgtt gatgggggtt accagcttga tccactgttg ctcttagaag gcccagaaag     2460

tctttgggca ttgccaagaa atcccggatt atgtggaaaa ccctcacttt ctcttcacgg     2520

ctgtaccaga aaatccctaa gacagatctt gccgtggact agcaatacct gcaagtgctg     2580

ccaatgggaa ctcaatttat tcctgggaac ctaacgagga gagcccaggc ctaggcagga     2640

ggcctggaac cctcttggct aaggtgctgt tcctgttcct gcaaggtctc cagaacccct     2700

ttggaaatgg tgaaggaacc agcccaatag aagtacagag ccagctgaca agtccttgta     2760

aagctcactc ctcagtcctt ggcacagcca tgttttgtct tctctcttgg tatttcttct     2820

ctcccaactt tagccatttt gccttggaat catgattaca attttttcct ttgcagatgc     2880

cttcctgggg gatactcctc cccaccctaa agggtcgcct gcaacttagg cggattgggt     2940

ctctctgctg tggcgttctc tcttgagaga ccctctgaat tttagcacaa agtgccttct     3000

gtttcacagc tgccaccacc tttagaggaa tttcgtcaga aaaatgtgga ggctccatat     3060

taatgcatta ttttttaaaa agttttgata actcttaaag catcatttgc acctatgtgg     3120

gaactttgcc tgttgcaaag tattgtggcc gagctgcagc tgggagcctg ctttctgcca     3180

gtcttgaggt tctgaagatc agctttgaaa ggaaagtatg tcctagctta gccattcaga     3240

agagaaaaat ggaatatcag agttacagtt gtcagtgaaa ctactttgga ttttaacctc     3300

ttagaggaag aaaaaaggtt agggaagtgt caactctgga tgaaggtgat gtgtttgcct     3360

ctcagtcttt cattcatagc ctgctagtga aaaggaagta aatgagattc ttttgtgtga     3420

ctttgtagtc tctttgtatt accaaatagt tggggtgttg actcctgtgt gttttgcaag     3480

aatgtgtggt aagcctgggt aaagagaagg aactgcggtg ttgggagagt ctttgtgttg     3540

gggagtggca ggggatgatt tgtttcaggg gaaaatgccc acattttaac ttttaaactt     3600

ctgaataaac tgtgtaaaaa cagtagtgga aaaaaaaaaa aaaaaaa                   3647


<210>  1196
<211>  1048
<212>  DNA
<213>  homo sapiens

<400>  1196
ataaaggggt ggcccgtaga agattccagc accctcccct aactccaggc cagactcctt       60

tcagctaaag gggagatctg gatggcatct acttcgtatg actattgcag agtgcccatg      120

gaagacgggg ataagcgctg taagcttctg ctggggatag gaattctggt gctcctgatc      180

atcgtgattc tgggggtgcc cttgattatc ttcaccatca aggccaacag cgaggcctgc      240

cgggacggcc ttcgggcagt gatggagtgt cgcaatgtca cccatctcct gcaacaagag      300

ctgaccgagg cccagaaggg ctttcaggat gtggaggccc aggccgccac ctgcaaccac      360

actgtgatgg ccctaatggc ttccctggat gcagagaagg cccaaggaca aaagaaagtg      420

gaggagcttg agggagagat cactacatta aaccataagc ttcaggacgc gtctgcagag      480

gtggagcgac tgagaagaga aaaccaggtc ttaagcgtga gaatcgcgga caagaagtac      540

taccccagct cccaggactc cagctccgct gcggcgcccc agctgctgat tgtgctgctg      600

ggcctcagcg ctctgctgca gtgagatccc aggaagctgg cacatcttgg aaggtccgtc      660

ctgctcggct tttcgcttga acattccctt gatctcatca gttctgagcg ggtcatgggg      720

caacacggtt agcggggaga gcacggggta gccggagaag ggcctctgga gcaggtctgg      780

aggggccatg gggaagtcct gggtgtgggg acacagtcgg gttgacccag ggctgtctcc      840

ctccagagcc tccctccgga caatgagtcc cccctcttgt ctcccaccct gagattgggc      900

atggggtgcg gtgtgggggg catgtgctgc ctgttgttat gggttttttt tgcggggggg      960

gttgcttttt tctggggtct ttgagctcca aaaaataaac acttcctttg agggagagca     1020

cacctgaaaa aaaaaaaaaa aaaaaaaa                                        1048


<210>  1197
<211>  7054
<212>  DNA
<213>  homo sapiens

<400>  1197
ccgcggcctg ggcctgcgcc gctcagctct ctggaaacta gcgcctcagc tgcgcggcgc       60

gtaggtcgcg gggagctccg aaccgccggc gcccggccat ggcggtctcc aggctagatc      120

gcctttttat tttactggat actggcacta ctcctgttac aagaaaagct gctgcacagc      180

aacttggaga agtggtgaag cttcatcccc atgaactaaa taatctcctg tctaaagtgt      240

tgatatattt aaggagtgca aattgggata cccggattgc agcaggacaa gctgttgaag      300

ctatagtgaa aaatgtacct gagtggaatc cagtgccgag aaccagacaa gaacctactt      360

ccgaaagttc tatggaagat tcacctacta cagagcgatt gaattttgac agatttgata      420

tatgtagatt gttacaacat ggtgcatcac tcctgggatc tgctggtgcc gaatttgaag      480

tccaagatga aaaatcaggt gaagtggatc ctaaagagag gatagcacgc caacgaaaat      540

tattacagaa gaaacttggc cttaatatgg gagaagcaat tggaatgagt actgaagaac      600

ttttcaatga tgaggatttg gattataccc caacttcagc atcctttgtt aacaaacaac      660

ctactcttca ggcagctgaa ttgattgact cagagtttcg agcaggaatg agcaatagac      720

aaaagaacaa agctaaaaga atggccaagt tatttgcaaa acagagatcc agggatgcag      780

tggaaactaa tgagaagagc aatgatagca ctgatgggga gccagaagaa aagagacgga      840

aaatagcaaa tgttgttatt aatcagtctg caaatgattc caaagtcttg attgataata      900

ttccagacag ctcttcctta attgaagaga caaatgaatg gcctttggaa agcttttgtg      960

aagaactttg caatgacctt tttaatccct cctgggaggt tcgacatggt gcaggcactg     1020

gacttaggga aattcttaaa gctcatggga aaagtggtgg taaaatgggt gacagcactt     1080

tagaagagat gattcagcag catcaagagt ggttggaaga cttggttatt agactccttt     1140

gtgtttttgc attagacaga tttggagact ttgtttctga tgaagttgtg gcaccagttc     1200

gtgaaacttg tgctcaaaca ttaggtgtgg ttttaaaaca catgaacgaa acaggagttc     1260

ataagactgt ggatgtgctg ctaaaattac ttacacaaga acaatgggaa gttagacatg     1320

gtggtctgct gggaataaaa tatgctttgg cagtccgtca ggatgtaatt aatactttat     1380

tgcctaaagt tttaactaga ataattgaag gactccagga tcttgatgat gatgtcagag     1440

ctgttgctgc agcatcatta gtgcctgtag tagaaagcct tgtctatctt cagacacaaa     1500

aggtgccctt cattataaat acattgtggg atgctcttct ggaattagat gatctaacag     1560

cttcaacaaa tagtattatg actctccttt catccttgtt aacttaccct caggtccaac     1620

aatgcagtat tcagcagtca ctgacagttt tagttccacg tgtctggcct tttttgcatc     1680

acactatatc atcagttcga agagcagcat tggaaactct gtttacgtta ttatcaacac     1740

aggaccagaa ctcttcatct tggcttatac ctatactgcc tgatatgctc cgacacattt     1800

ttcagttctg tgttttggaa agcagccagg aaattctgga ccttattcac aaggtttgga     1860

tggaactgtt gagtaaggct tcagttcagt atgtggtagc agctgcttgc ccatggatgg     1920

gtgcttggct ttgcttgatg atgcagcctt ctcatttacc tatcgattta aatatgttgc     1980

tagaagtaaa agctagagcc aaggaaaaaa caggtggtaa ggtgcgccaa ggccaaagcc     2040

agaataaaga agtacttcag gagtatattg caggtgccga caccatcatg gaagacccag     2100

ccaccaggga ttttgtagtt atgcgggcca gaatgatggc agccaagttg ttaggagcac     2160

tttgttgctg tatttgtgat ccaggtgtaa atgtggtaac tcaagaaatt aaaccagctg     2220

aatccctggg ccagttacta ctcttccatt tgaactccaa gtctgcttta cagaggatta     2280

gtgtagcttt ggtaatctgt gaatgggctg ctttacaaaa ggagtgtaaa gctgttacct     2340

tagctgtgca gccgcgttta cttgatatcc tttcagaaca tttatattat gacgaaattg     2400

ccgttccatt cacacgaatg cagaatgaat gtaaacaact tatatcatca ttagctgatg     2460

tacatattga agttggtaat cgagtaaaca acaatgtttt aacaatagat caagctagtg     2520

acttggtcac tactgttttt aatgaagcca catcatcttt cgatttaaat cctcaagtgt     2580

tacaacagtt agatagtaaa cgacagcagg tccaaatgac agttacagag accaaccagg     2640

agtggcaagt gttgcagttg agagtgcata cttttgctgc ctgtgcagtt gtgagcttgc     2700

agcagcttcc ggagaaatta aatcctatca taaaaccatt aatggagaca attaaaaaag     2760

aagagaatac actagtgcaa aactatgcag ctcagtgcat agctaaactc cttcagcagt     2820

gcacaacaag gacgccctgt cccaattcaa aaattattaa aaacctctgt agctcacttt     2880

gtgtggaccc atatctaact ccttgtgtca catgtccagt accaacacaa agtggccagg     2940

aaaattctaa aggatccacc tcagaaaaag atggaatgca ccatactgtc accaagcaca     3000

gaggtataat tacactctac aggcaccaga aagctgcctt tgctatcaca agtaggcgag     3060

gtcctacccc caaagcagta aaagctcaaa tagcagatct tcctgcagga agtagtggaa     3120

atattcttgt tgaacttgat gaggcccaga agccttacct ggtacaacgg agaggagctg     3180

aatttgcttt gacaactata gtaaagcatt ttggtggtga aatggcagtg aagttgccac     3240

atctctggga tgctatggtt ggcccattga ggaatacaat cgacataaat aattttgatg     3300

gaaaatccct cctggataag ggagatagcc ctgctcaaga attggtgaat tctctgcagg     3360

tttttgaaac agcagcagct tcaatggatt ctgagcttca tcccttgttg gtccagcatt     3420

tgccacatct ttatatgtgc cttcaatacc ccagtactgc agtgaggcac atggctgctc     3480

gttgtgtagg tgtcatgagc aaaatagcta ccatggaaac aatgaatatt tttttggaga     3540

aggttcttcc gtggctggga gcaattgatg acagtgtcaa acaagagggt gcaattgaag     3600

cacttgcctg tgtaatggaa caactagatg ttggtattgt tccatatatt gtccttttag     3660

ttgttcctgt attaggaaga atgagtgatc agacagacag tgtgagattc atggccacgc     3720

agtgctttgc aacgctaatt agactcatgc cacttgaggc aggcattcca gaccctccaa     3780

acatgtcagc agaattaatc caattgaaag ccaaggagcg acactttttg gagcaattgt     3840

tagatgggaa aaaattggaa aattataaaa ttccagtacc aatcaatgct gaactcagaa     3900

aatatcagca ggatggtgtg aactggttag catttcttaa taagtataaa cttcatggaa     3960

ttctgtgtga tgacatgggt ttaggaaaaa ctttacagtc catctgcatt ctagcaggag     4020

atcattgtca tagggcccag gaatatgcaa gatcaaaatt agcagaatgt atgccacttc     4080

cttccttagt ggtttgtccg ccaacattaa caggccattg ggtggatgaa gtaggtaaat     4140

tttgctctag agaatatctc aacccgttgc attacactgg acctcccact gaaagaataa     4200

ggttacagca ccaagtaaaa aggcacaatc taatagtggc ttcatatgat gttgtgagga     4260

atgacataga tttctttaga aatattaaat ttaactactg cattcttgat gaaggccatg     4320

tcatcaaaaa tggaaaaaca aagttgtcaa aagcagtaaa acaactgact gctaattata     4380

ggattattct ttctggaaca ccaatccaga acaacgtttt ggagctgtgg tcattatttg     4440

atttcctcat gccaggattt ttgggtactg aacgccagtt tgctgctcga tatggtaaac     4500

ctatattagc aagtagggat gctcgaagct ccagtcgaga gcaagaagca ggtgttcttg     4560

ctatggatgc gctgcaccgc caagtactac cgtttctttt gagaagaatg aaagaagatg     4620

ttttgcagga tcttccacct aaaattattc aagactatta ttgtactctt agtcctctcc     4680

aggttcagct ctatgaagat tttgctaagt ctcgtgccaa gtgtgatgtt gatgaaacag     4740

tttcttcagc tacactttct gaagaaactg aaaaaccaaa gcttaaagct acaggccacg     4800

tattccaggc attacagtac ttacgtaaac tgtgcaacca tccagcatta gtcttaacac     4860

ctcaacatcc agaattcaag accactgccg aaaaactggc agttcagaat tcttctctac     4920

atgatattca acatgcccct aagctctcag ctttgaaaca attgctgttg gactgcggtt     4980

tgggaaatgg cagcacttcc gagagtggca cagagtctgt tgtggcccag cacaggatac     5040

tgatattctg tcagctgaaa agcatgcttg atatagtaga gcatgatctc ctcaaacctc     5100

acttgccctc tgtcacttat ttgagattag atggcagcat acctcctggt cagaggcatt     5160

ccattgtttc ccggtttaat aatgatccat ctatagacgt tctgttactt accactcacg     5220

ttggtggcct gggacttaat ttgacaggcg ctgacacagt agtatttgtg gagcatgact     5280

ggaatcctat gcgagatcta caagccatgg accgggccca tcgcattggg cagaaacgtg     5340

tggttaacgt ataccgattg ataaccagag gaacattgga agaaaaaata atggggttgc     5400

agaaattcaa gatgaacata gcgaatactg ttattagcca agagaattct agtttgcaga     5460

gcatggggac tgatcagctt cttgatctgt ttactcttga taaggatggc aaagcagaaa     5520

aagctgacac ctctacttct gggaaagcaa gtatgaaatc aattcttgaa aacctgagtg     5580

atctttggga tcaagagcag tatgattcag agtacagcct ggaaaatttt atgcattctc     5640

tcaagtaact atcaaatatt gtaaatgcaa ttgctgctag ttcagttaca tttctgctga     5700

tattcagcaa atttctaagt ttatggtgaa cttttaactc aatgtgtaaa tagatctgga     5760

gaatattcag cataatgctg gctcttgttt cactggggga aacaagttat tctcaaatat     5820

ttgcactgta ttaaatttaa atgttaatgt gaaatggttt aaattttaca tgctgaaaag     5880

ctgcagagca gaggaaccaa accaggttta tttgtgctac caggaggtgt tcttaatggg     5940

aacaggcctc ctatctttag tcactttgta caggatgata tccatgagta ctttagtgtt     6000

tgtatatgtt ttttctttta aatagaactt gtttttataa ttgatttaaa atagggcttt     6060

ttttctataa aagccttaat gagccataat tttaagaata taagaataat gactatgata     6120

ttggtcagtc ttagaacatg aaaatgtcag acaatgaatt taatcgggcc cttggtggaa     6180

acatttatat atttaatgca gatgcatagt gtttttcaaa tctttaacat cattttttca     6240

acttttaaga tataatatca actattctaa atacaggtaa tggtatattt aaggctacca     6300

taacatccta tttagagggt ggtttttttt aatttatcta atggctacga tatagccaga     6360

ttcaaataac atatgtactc aataggtttc aatcatatat ataatatatt ttttgtaact     6420

atgaacatac acagttttcc agaaatagat tttacactgt ttagaattcc aacacctaca     6480

gtggaaagac tgtttattgt agtaatgcat ggctgaagca taaaagggag agagaatttc     6540

tttatataca caaacataca tgaatatgca tatctatatg catagatgta cctatcctgc     6600

acccaaaaag gtgcctggta ttggcactaa aatcatgtag ttatactggg cagcaataat     6660

aattgggcat gaggctgatt actcaatggt gagggtaggt atatgtagat agatgtgcat     6720

gtatgtgttt gtatatataa ttttataagt ttcacgcata aattaataca tgcctgtgtg     6780

catacatatg tatgggatat atttgtatat atatgtacag gtaataaaca tccccaaggt     6840

ttgtggctgg ccatacacat aggcatcagt ttaacaacca tcagacctca gctgtacaat     6900

aacaggtgtt ttgtttaatt aaaattatac tgttctgcag catttagaca tttgtcacat     6960

ttcattagct ttgacaacca tactgtaaca ttaaacctag cattccacaa gagaataaat     7020

ataagattga aactgtaaaa aaaaaaaaaa aaaa                                 7054


<210>  1198
<211>  3785
<212>  DNA
<213>  homo sapiens

<400>  1198
gtaacgccgc gcaccctatc aggcggccac agggagcgcg cccgcggcct cgccctttct       60

cgcccctccc ttctcccctc tgggtccagc ctcagactga ggcttggaga caggagcatt      120

ccactcgcca cttcggcgcg cccccatgcc ctcttgtgcg cgtgcgcaga ggcggaccgc      180

aaggctaggg cgtgagggaa gggcgggcgt acgcccttgc gtgcgtctca ggcagcgcgc      240

acgccggcgt gagagggcac ggggaaaagg tggctctggc cggggtggct cggtttcctg      300

gggctatgta actgagctcg tcgacttagg ggtccttctt cgctgccctc gccgcgtgct      360

agcagggagt ttccgctcgg gagagagact gtcctcacgc ccgctgcgcc tcctcgacgg      420

cagagcaggc ttgctcgccc gtgggagcgt cccggccgag aagccctgag gggggagggg      480

aggccatttt gtcccgaccg actccccgga accgggcgga gcggctggga gaggctgcgg      540

agccgcggtc gccgccctcg gaggcactgg acgccgccac tgtcggggct tcctcaaagc      600

tgttcgtagg tcgcccgcgc cgtctcgagc ctttttccca cgcttccccg gtcctccggc      660

ctgagaacgc ccgagtgagg agttggccgt agtgagaggg accgatccct tggggccgcc      720

ggcggcgaga gcccgagccg ctcctcccaa tggcgaagaa gacgtacgac ctgcttttca      780

agctgctcct gatcggggat tccggagtgg ggaagacctg cgtccttttt cgtttttcgg      840

atgatgcctt caatactacc tttatttcca ccataggaat agacttcaag atcaaaacag      900

ttgaattaca aggaaagaag atcaagctac agatatggga tacagcaggc caggagcgat      960

ttcacaccat cacaacctcc tactacagag gcgcaatggg tatcatgcta gtatatgaca     1020

tcaccaatgg taaaagtttt gaaaacatca gcaaatggct tagaaacata gatgagcatg     1080

ccaatgaaga tgtggaaaga atgttactag gaaacaagtg tgatatggac gacaaaagag     1140

ttgtacctaa aggaaaagga gaacagattg caagggagca tggtattagg ttttttgaga     1200

ctagtgcaaa agcaaatata aacatcgaaa aggcgttcct cacgttagct gaagatatcc     1260

ttcgaaagac ccctgtaaaa gagcccaaca gtgaaaatgt agatatcagc agtggaggag     1320

gcgtgacagg ctggaagagc aaatgctgct gagcattctc ctgttccatc agttgccatc     1380

cactaccccg ttttctcttc ttgctgcaaa ataaaccact ctgtccattt ttaactctaa     1440

acagatattt ttgtttctca tcttaactat ccaagccacc tattttattt gttctttcat     1500

ctgtgactgc ttgctgactt tatcataatt ttcttcaaac aaaaaaatgt atagaaaaat     1560

catgtctgtg agttcatttt taaatgtact tgctcagctc aactgcattt cagttgtatt     1620

atagtccagt tcttatcaac attaaaacct atagcaatca tttcaaatct attctgcaaa     1680

ttgtataaga ataaagttag aattaacaat tttattttgt acaacagtgg aattttctgt     1740

catggataat gtgcttgagt ccctataatc tatagacatg tgatagcaaa agaaacaaac     1800

aaaagccagg aaaacactca ttttcgcctt gaatatgtaa atgggattaa ttttgtcctg     1860

tgccttatgt ggaaaggaac ttctttggtt ttcctttttt gttctggtgg aagcatgtgc     1920

aggagacata tcatccaaac ataaaccatt aaaatgtttg tggtttgctt ggctgtaatt     1980

ttcaaagtag ttaattgagg acaaagggta atgcagaagt gatagctttg gtttgctgag     2040

tcttgtttta agtggccttg atatttaaaa ctattcctgc caccatttct tctccttggc     2100

cacttcttcc ttgcgtctcc ctgcatgctg ctttatttgc ttctccctcc ccaaccacct     2160

catggtatat ttaagagtga aagggacaaa ctagtaggtt tgtcaagttt aatataaagc     2220

actgatgtaa cttgctaggt aaacggaaag ataagttcta actgcctact atccaatgtc     2280

agttaattgg tgtcttcccc cctcatttgc tctcttccct aaaatgtgtc ccagatgcct     2340

tcatttgctg ttttacttct atgttctgct tttcctcctc tctttgttcc cttcctgtct     2400

atccattgag tttatgaaat ggaagagtta actgcatgca ctagtgtttg gagggtgttg     2460

tggtttgtct ttctaattag gtgtatagcc tattcacttt cctagaataa atctcttaac     2520

ctaaatttga gtagtctgca ttttggcaac tcctctagca gcttggtagc ctagtacagg     2580

ttgttttttt aaaaaaggaa aagcaggaag gaggagtgaa ttttattaac atgtttgcca     2640

aatgtattga gatttggcct ctgaagaaca ctttttcagt gttaagtttc tttaccttaa     2700

gattcagaaa tactttagaa tattattaat tttaagtcct gtctttacat ccttttggaa     2760

aacttgtatt accatgggtt tggaaaaagg acaacgaaag gcttttcatg taaagataag     2820

atctttagct atctctaacc ctgtcctttt ttcactgcat tttttctagt tttgcttcat     2880

tgcttatcat taggataggg taagtgaagt ttgctatgct gctagcatcc taagatgata     2940

cctttgttga aagaattgtg aatagcatga ttcatttcta gcagaggctg agtttaggac     3000

agcagcttcc attgagaagt ctttctgtgt cgtgaatagc attttaatga cctcttggct     3060

cacataagca aacaacatag ggacgtatct gctatgaaaa tccacaaatt tttcagatag     3120

tgccctaaaa acaattttat atgcctcact ggttgttatt cttaggttat tcccacactt     3180

gactttatca ttgtttacta ctagtaaaaa gcagcattgc caaataatcc ctaattttcc     3240

actaaaaata taatgaaatg atgttaagct ttttgaaaag tttaggttaa acctactgtt     3300

gttagattaa tgtatttgtt gcttcccttt atctggaatg tggcattagc ttttttattt     3360

taaccctctt taattcttat tcaattccat gacttaaggt tggagagcta aacactggga     3420

tttttggata acagactgac agttttgcat aattataatc ggcattgtac atagaaagga     3480

tatggctacc ttttgttaaa tctgcacttt ctaaatatca aaaaagggaa atgaagtata     3540

aatcaatttt tgtataatct gtttgaaaca tgagttttat ttgcttaata ttagggcttt     3600

gccccttttc tgtaagtctc ttgggatcct gtgtagaagc tgttctcatt aaacaccaaa     3660

cagttaagtc cattctctgg tactagctac aaattcggtt tcatattcta cttaacaatt     3720

taaataaact gaaatatttc tagatggtct acttctgttc atataaaaac aaaacttgat     3780

ttcca                                                                 3785


<210>  1199
<211>  2392
<212>  DNA
<213>  homo sapiens

<400>  1199
aggaagtgcg gcaccttagt gatcccgagt ttaagccgag agttgctcac gtgaccgaga       60

tctcacatga cgtaggcgct cacgtgatta ctcgcttacg tgagcagaag tagttctggt      120

cgtcgtctac cgtctcgcta tagccgtttg agggaagaag gaggaaaatt acccggtatc      180

gttagagcta caccaaaatt gcattgagcc aaacttgcca ccaagagccc aacaatcacc      240

atgatgctga gcacggaagg cagggagggg ttcgtggtga aggtcagggg cctaccctgg      300

tcctgctcag ccgatgaagt gatgcgcttc ttctctgatt gcaagatcca aaatggcaca      360

tcaggtattc gtttcatcta caccagagaa ggcagaccaa gtggtgaagc atttgttgaa      420

cttgaatctg aagaggaagt gaaattggct ttgaagaagg acagagaaac catgggacac      480

agatacgttg aagtattcaa gtctaacagt gttgaaatgg attgggtgtt gaagcataca      540

ggtccgaata gccctgatac tgccaacgat ggcttcgtcc ggcttagagg actcccattt      600

ggctgtagca aggaagagat tgttcagttc ttttcagggt tggaaattgt gccaaatggg      660

atgacactgc cagtggactt tcaggggcga agcacagggg aagcctttgt gcagtttgct      720

tcacaggaga tagctgagaa ggccttaaag aaacacaagg aaagaatagg gcacaggtac      780

attgagatct tcaagagtag ccgagctgaa gttcgaaccc actatgatcc ccctcgaaag      840

ctcatggcta tgcagcggcc aggtccctat gataggccgg gggctggcag agggtataat      900

agcattggca gaggagctgg gtttgaaagg atgaggcgtg gtgcctatgg tggagggtat      960

ggaggctatg atgactatgg tggctataat gatggatatg gctttgggtc tgatagattt     1020

ggaagagacc tcaattactg tttttcagga atgtctgatc atagatacgg agatggtggg     1080

tccagtttcc agagcaccac agggcactgt gtacacatga gggggttacc ttacagagcc     1140

actgagaatg atatttataa tttcttctca cctcttaatc ccatgagagt acatattgaa     1200

attggacccg atggcagagt taccggtgag gcagatgttg aatttgctac tcatgaagat     1260

gctgtggcag ctatggcaaa agacaaagct aatatgcaac acagatatgt ggagctcttc     1320

ttaaattcta ctgcaggaac aagtgggggt gcttacgatc acagctatgt agaacttttt     1380

ttgaattcta cagcaggggc aagtggtggc gcttatggta gccaaatgat gggagggatg     1440

ggcttatcca accagtctag ttatggaggt cctgctagcc agcagctgag tggtggttat     1500

ggaggtggtt atggtggtca gagcagtatg agtggatatg accaagttct gcaggaaaac     1560

tccagtgact atcagtcaaa ccttgcttag gtagagaagg agcactaaat agctactcca     1620

gatataaaag ctgtacattt gtgggagttg aatagaatgg gagggatgtt tagtatatcc     1680

agtatgattg gtaaatggga aatataattg attctgatca ctcttggtca gcttctcttt     1740

ctttatcttt ctttctcctt ttttaagaaa acgagttaag tttaacagtt ttgcattaca     1800

ggcttgtgat tcatgcttac tgtaaagtgg aagttgagat tattttaaaa cttcaagctc     1860

agtaattttg aacactgaaa cattcatcta ggacataata acaaagttca gtattgacca     1920

taactgttaa aacaattttt agctttcctc aagttagtta tgttgtagga gtgtacctaa     1980

gcagtaagcg tatttaggtt aatgcagttt cacttatgtt aaatgttgct cttataccac     2040

aaatacattg aaaacttcgg atgcatgttg agaaacatgc ctttctgtaa aactcaaata     2100

taggagctgt gtctacgatt caaagtgaaa acatttggca tgtttgttaa ttctagcttt     2160

ttggtttaat atcctgtaag gcacgtgagt gtacactttt ttttttttta aggatacggg     2220

acaattttaa gatgtaatac caatacttta gaagtttggt cgtgtcgttt gtatgaaaat     2280

ctgaggcttt ggtttaaatc tttccttgta ttgtgatttc catttagatg tattgtacta     2340

agtgaaactt gttaaataaa tcttcctttt aaaaactgga aaaaatcttg aa             2392


<210>  1200
<211>  2380
<212>  DNA
<213>  homo sapiens

<400>  1200
aggaagtgcg gcaccttagt gatcccgagt ttaagccgag agttgctcac gtgaccgaga       60

tctcacatga cgtaggcgct cacgtgatta ctcgcttacg tgagcagaag tagttctggt      120

cgtcgtctac cgtctcgcta tagccgtttg agggaagaag gaggaaaatt acccgctaca      180

ccaaaattgc attgagccaa acttgccacc aagagcccaa caatcaccat gatgctgagc      240

acggaaggca gggaggggtt cgtggtgaag gtcaggggcc taccctggtc ctgctcagcc      300

gatgaagtga tgcgcttctt ctctgattgc aagatccaaa atggcacatc aggtattcgt      360

ttcatctaca ccagagaagg cagaccaagt ggtgaagcat ttgttgaact tgaatctgaa      420

gaggaagtga aattggcttt gaagaaggac agagaaacca tgggacacag atacgttgaa      480

gtattcaagt ctaacagtgt tgaaatggat tgggtgttga agcatacagg tccgaatagc      540

cctgatactg ccaacgatgg cttcgtccgg cttagaggac tcccatttgg ctgtagcaag      600

gaagagattg ttcagttctt ttcagggttg gaaattgtgc caaatgggat gacactgcca      660

gtggactttc aggggcgaag cacaggggaa gcctttgtgc agtttgcttc acaggagata      720

gctgagaagg ccttaaagaa acacaaggaa agaatagggc acaggtacat tgagatcttc      780

aagagtagcc gagctgaagt tcgaacccac tatgatcccc ctcgaaagct catggctatg      840

cagcggccag gtccctatga taggccgggg gctggcagag ggtataatag cattggcaga      900

ggagctgggt ttgaaaggat gaggcgtggt gcctatggtg gagggtatgg aggctatgat      960

gactatggtg gctataatga tggatatggc tttgggtctg atagatttgg aagagacctc     1020

aattactgtt tttcaggaat gtctgatcat agatacggag atggtgggtc cagtttccag     1080

agcaccacag ggcactgtgt acacatgagg gggttacctt acagagccac tgagaatgat     1140

atttataatt tcttctcacc tcttaatccc atgagagtac atattgaaat tggacccgat     1200

ggcagagtta ccggtgaggc agatgttgaa tttgctactc atgaagatgc tgtggcagct     1260

atggcaaaag acaaagctaa tatgcaacac agatatgtgg agctcttctt aaattctact     1320

gcaggaacaa gtgggggtgc ttacgatcac agctatgtag aacttttttt gaattctaca     1380

gcaggggcaa gtggtggcgc ttatggtagc caaatgatgg gagggatggg cttatccaac     1440

cagtctagtt atggaggtcc tgctagccag cagctgagtg gtggttatgg aggtggttat     1500

ggtggtcaga gcagtatgag tggatatgac caagttctgc aggaaaactc cagtgactat     1560

cagtcaaacc ttgcttaggt agagaaggag cactaaatag ctactccaga tataaaagct     1620

gtacatttgt gggagttgaa tagaatggga gggatgttta gtatatccag tatgattggt     1680

aaatgggaaa tataattgat tctgatcact cttggtcagc ttctctttct ttatctttct     1740

ttctcctttt ttaagaaaac gagttaagtt taacagtttt gcattacagg cttgtgattc     1800

atgcttactg taaagtggaa gttgagatta ttttaaaact tcaagctcag taattttgaa     1860

cactgaaaca ttcatctagg acataataac aaagttcagt attgaccata actgttaaaa     1920

caatttttag ctttcctcaa gttagttatg ttgtaggagt gtacctaagc agtaagcgta     1980

tttaggttaa tgcagtttca cttatgttaa atgttgctct tataccacaa atacattgaa     2040

aacttcggat gcatgttgag aaacatgcct ttctgtaaaa ctcaaatata ggagctgtgt     2100

ctacgattca aagtgaaaac atttggcatg tttgttaatt ctagcttttt ggtttaatat     2160

cctgtaaggc acgtgagtgt acactttttt tttttttaag gatacgggac aattttaaga     2220

tgtaatacca atactttaga agtttggtcg tgtcgtttgt atgaaaatct gaggctttgg     2280

tttaaatctt tccttgtatt gtgatttcca tttagatgta ttgtactaag tgaaacttgt     2340

taaataaatc ttccttttaa aaactggaaa aaatcttgaa                           2380


<210>  1201
<211>  881
<212>  DNA
<213>  homo sapiens

<400>  1201
gagtcctctc agccgcccga gggcgctgcg ctgagcctta cactctatga ttgctcctac       60

cgactcccat gaggaagtgc gatcgggaac ctcctatata cttccgtttg cctcgcggtt      120

tctttctttc cgcgccgata gcgctcacgc aagcatggtt aacgtcccta aaacccgccg      180

gactttctgt aagaagtgtg gcaagcacca accccataaa gtgacacagt acaagaaggg      240

caaggattct ctgtacgccc agggaaagcg gcgttatgac aggaagcaga gtggctatgg      300

tgggcaaact aagccgattt tccggaaaaa ggctaaaact acaaagaaga ttgtgctaag      360

gcttgagtgc gttgagccca actgcagatc taagagaatg ctggctatta aaagatgcaa      420

gcattttgaa ctgggaggag ataagaagag aaagggccaa gtgatccagt tctaagtgtc      480

atcttttatt atgaagacaa taaaatcttg agtttatgtt cacttcattt gtttgctgtt      540

catcttttgg gagggaataa gctagagcca tcaatacaat tccgcttgtg gggaaattta      600

tgcctcttac tggtactact tgttttgcat tgaagctgac tggttgagtt cacatcatat      660

gttgcaattt tctaatttgg cacttcaatc actaggggcc ttatgaggca gtttgtcatt      720

atgcaatggt tattggttat catgtgagta gacacatttc aggctaatag ggagaagtca      780

gtaacacatt catagtgaat atgagatgtc tttgctaaga gttaagtgtc agatctttgt      840

tataacagtt aatttaataa agaattttgg cattgttctt c                          881


<210>  1202
<211>  2392
<212>  DNA
<213>  homo sapiens

<400>  1202
aggaagtgcg gcaccttagt gatcccgagt ttaagccgag agttgctcac gtgaccgaga       60

tctcacatga cgtaggcgct cacgtgatta ctcgcttacg tgagcagaag tagttctggt      120

cgtcgtctac cgtctcgcta tagccgtttg agggaagaag gaggaaaatt acccggtatc      180

gttagagcta caccaaaatt gcattgagcc aaacttgcca ccaagagccc aacaatcacc      240

atgatgctga gcacggaagg cagggagggg ttcgtggtga aggtcagggg cctaccctgg      300

tcctgctcag ccgatgaagt gatgcgcttc ttctctgatt gcaagatcca aaatggcaca      360

tcaggtattc gtttcatcta caccagagaa ggcagaccaa gtggtgaagc atttgttgaa      420

cttgaatctg aagaggaagt gaaattggct ttgaagaagg acagagaaac catgggacac      480

agatacgttg aagtattcaa gtctaacagt gttgaaatgg attgggtgtt gaagcataca      540

ggtccgaata gccctgatac tgccaacgat ggcttcgtcc ggcttagagg actcccattt      600

ggctgtagca aggaagagat tgttcagttc ttttcagggt tggaaattgt gccaaatggg      660

atgacactgc cagtggactt tcaggggcga agcacagggg aagcctttgt gcagtttgct      720

tcacaggaga tagctgagaa ggccttaaag aaacacaagg aaagaatagg gcacaggtac      780

attgagatct tcaagagtag ccgagctgaa gttcgaaccc actatgatcc ccctcgaaag      840

ctcatggcta tgcagcggcc aggtccctat gataggccgg gggctggcag agggtataat      900

agcattggca gaggagctgg gtttgaaagg atgaggcgtg gtgcctatgg tggagggtat      960

ggaggctatg atgactatgg tggctataat gatggatatg gctttgggtc tgatagattt     1020

ggaagagacc tcaattactg tttttcagga atgtctgatc atagatacgg agatggtggg     1080

tccagtttcc agagcaccac agggcactgt gtacacatga gggggttacc ttacagagcc     1140

actgagaatg atatttataa tttcttctca cctcttaatc ccatgagagt acatattgaa     1200

attggacccg atggcagagt taccggtgag gcagatgttg aatttgctac tcatgaagat     1260

gctgtggcag ctatggcaaa agacaaagct aatatgcaac acagatatgt ggagctcttc     1320

ttaaattcta ctgcaggaac aagtgggggt gcttacgatc acagctatgt agaacttttt     1380

ttgaattcta cagcaggggc aagtggtggc gcttatggta gccaaatgat gggagggatg     1440

ggcttatcca accagtctag ttatggaggt cctgctagcc agcagctgag tggtggttat     1500

ggaggtggtt atggtggtca gagcagtatg agtggatatg accaagttct gcaggaaaac     1560

tccagtgact atcagtcaaa ccttgcttag gtagagaagg agcactaaat agctactcca     1620

gatataaaag ctgtacattt gtgggagttg aatagaatgg gagggatgtt tagtatatcc     1680

agtatgattg gtaaatggga aatataattg attctgatca ctcttggtca gcttctcttt     1740

ctttatcttt ctttctcctt ttttaagaaa acgagttaag tttaacagtt ttgcattaca     1800

ggcttgtgat tcatgcttac tgtaaagtgg aagttgagat tattttaaaa cttcaagctc     1860

agtaattttg aacactgaaa cattcatcta ggacataata acaaagttca gtattgacca     1920

taactgttaa aacaattttt agctttcctc aagttagtta tgttgtagga gtgtacctaa     1980

gcagtaagcg tatttaggtt aatgcagttt cacttatgtt aaatgttgct cttataccac     2040

aaatacattg aaaacttcgg atgcatgttg agaaacatgc ctttctgtaa aactcaaata     2100

taggagctgt gtctacgatt caaagtgaaa acatttggca tgtttgttaa ttctagcttt     2160

ttggtttaat atcctgtaag gcacgtgagt gtacactttt ttttttttta aggatacggg     2220

acaattttaa gatgtaatac caatacttta gaagtttggt cgtgtcgttt gtatgaaaat     2280

ctgaggcttt ggtttaaatc tttccttgta ttgtgatttc catttagatg tattgtacta     2340

agtgaaactt gttaaataaa tcttcctttt aaaaactgga aaaaatcttg aa             2392


<210>  1203
<211>  4326
<212>  DNA
<213>  homo sapiens

<400>  1203
gctgagcgcg gagccgcccg gtgattggtg ggggcggaag ggggccgggc gccagcgctg       60

ccttttctcc tgccgggtag tttcgctttc ctgcgcagag tctgcggagg ggctcggctg      120

caccgggggg atcgcgcctg gcagacccca gaccgagcag aggcgaccca gcgcgctcgg      180

gagaggctgc accgccgcgc ccccgcctag cccttccgga tcctgcgcgc agaaaagttt      240

catttgctgt atgccatcct cgagagctgt ctaggttaac gttcgcactc tgtgtatata      300

acctcgacag tcttggcacc taacgtgctg tgcgtagctg ctcctttggt tgaatcccca      360

ggcccttgtt ggggcacaag gtggcaggat gtctcagtgg tacgaacttc agcagcttga      420

ctcaaaattc ctggagcagg ttcaccagct ttatgatgac agttttccca tggaaatcag      480

acagtacctg gcacagtggt tagaaaagca agactgggag cacgctgcca atgatgtttc      540

atttgccacc atccgttttc atgacctcct gtcacagctg gatgatcaat atagtcgctt      600

ttctttggag aataacttct tgctacagca taacataagg aaaagcaagc gtaatcttca      660

ggataatttt caggaagacc caatccagat gtctatgatc atttacagct gtctgaagga      720

agaaaggaaa attctggaaa acgcccagag atttaatcag gctcagtcgg ggaatattca      780

gagcacagtg atgttagaca aacagaaaga gcttgacagt aaagtcagaa atgtgaagga      840

caaggttatg tgtatagagc atgaaatcaa gagcctggaa gatttacaag atgaatatga      900

cttcaaatgc aaaaccttgc agaacagaga acacgagacc aatggtgtgg caaagagtga      960

tcagaaacaa gaacagctgt tactcaagaa gatgtattta atgcttgaca ataagagaaa     1020

ggaagtagtt cacaaaataa tagagttgct gaatgtcact gaacttaccc agaatgccct     1080

gattaatgat gaactagtgg agtggaagcg gagacagcag agcgcctgta ttggggggcc     1140

gcccaatgct tgcttggatc agctgcagaa ctggttcact atagttgcgg agagtctgca     1200

gcaagttcgg cagcagctta aaaagttgga ggaattggaa cagaaataca cctacgaaca     1260

tgaccctatc acaaaaaaca aacaagtgtt atgggaccgc accttcagtc ttttccagca     1320

gctcattcag agctcgtttg tggtggaaag acagccctgc atgccaacgc accctcagag     1380

gccgctggtc ttgaagacag gggtccagtt cactgtgaag ttgagactgt tggtgaaatt     1440

gcaagagctg aattataatt tgaaagtcaa agtcttattt gataaagatg tgaatgagag     1500

aaatacagta aaaggattta ggaagttcaa cattttgggc acgcacacaa aagtgatgaa     1560

catggaggag tccaccaatg gcagtctggc ggctgaattt cggcacctgc aattgaaaga     1620

acagaaaaat gctggcacca gaacgaatga gggtcctctc atcgttactg aagagcttca     1680

ctcccttagt tttgaaaccc aattgtgcca gcctggtttg gtaattgacc tcgagacgac     1740

ctctctgccc gttgtggtga tctccaacgt cagccagctc ccgagcggtt gggcctccat     1800

cctttggtac aacatgctgg tggcggaacc caggaatctg tccttcttcc tgactccacc     1860

atgtgcacga tgggctcagc tttcagaagt gctgagttgg cagttttctt ctgtcaccaa     1920

aagaggtctc aatgtggacc agctgaacat gttgggagag aagcttcttg gtcctaacgc     1980

cagccccgat ggtctcattc cgtggacgag gttttgtaag gaaaatataa atgataaaaa     2040

ttttcccttc tggctttgga ttgaaagcat cctagaactc attaaaaaac acctgctccc     2100

tctctggaat gatgggtgca tcatgggctt catcagcaag gagcgagagc gtgccctgtt     2160

gaaggaccag cagccgggga ccttcctgct gcggttcagt gagagctccc gggaaggggc     2220

catcacattc acatgggtgg agcggtccca gaacggaggc gaacctgact tccatgcggt     2280

tgaaccctac acgaagaaag aactttctgc tgttactttc cctgacatca ttcgcaatta     2340

caaagtcatg gctgctgaga atattcctga gaatcccctg aagtatctgt atccaaatat     2400

tgacaaagac catgcctttg gaaagtatta ctccaggcca aaggaagcac cagagccaat     2460

ggaacttgat ggccctaaag gaactggata tatcaagact gagttgattt ctgtgtctga     2520

agttcaccct tctagacttc agaccacaga caacctgctc cccatgtctc ctgaggagtt     2580

tgacgaggtg tctcggatag tgggctctgt agaattcgac agtatgatga acacagtata     2640

gagcatgaat ttttttcatc ttctctggcg acagttttcc ttctcatctg tgattccctc     2700

ctgctactct gttccttcac atcctgtgtt tctagggaaa tgaaagaaag gccagcaaat     2760

tcgctgcaac ctgttgatag caagtgaatt tttctctaac tcagaaacat cagttactct     2820

gaagggcatc atgcatctta ctgaaggtaa aattgaaagg cattctctga agagtgggtt     2880

tcacaagtga aaaacatcca gatacaccca aagtatcagg acgagaatga gggtcctttg     2940

ggaaaggaga agttaagcaa catctagcaa atgttatgca taaagtcagt gcccaactgt     3000

tataggttgt tggataaatc agtggttatt tagggaactg cttgacgtag gaacggtaaa     3060

tttctgtggg agaattctta catgttttct ttgctttaag tgtaactggc agttttccat     3120

tggtttacct gtgaaatagt tcaaagccaa gtttatatac aattatatca gtcctctttc     3180

aaaggtagcc atcatggatc tggtaggggg aaaatgtgta ttttattaca tctttcacat     3240

tggctattta aagacaaaga caaattctgt ttcttgagaa gagaatatta gctttactgt     3300

ttgttatggc ttaatgacac tagctaatat caatagaagg atgtacattt ccaaattcac     3360

aagttgtgtt tgatatccaa agctgaatac attctgcttt catcttggtc acatacaatt     3420

atttttacag ttctcccaag ggagttaggc tattcacaac cactcattca aaagttgaaa     3480

ttaaccatag atgtagataa actcagaaat ttaattcatg tttcttaaat gggctacttt     3540

gtcctttttg ttattagggt ggtatttagt ctattagcca caaaattggg aaaggagtag     3600

aaaaagcagt aactgacaac ttgaataata caccagagat aatatgagaa tcagatcatt     3660

tcaaaactca tttcctatgt aactgcattg agaactgcat atgtttcgct gatatatgtg     3720

tttttcacat ttgcgaatgg ttccattctc tctcctgtac tttttccaga cacttttttg     3780

agtggatgat gtttcgtgaa gtatactgta tttttacctt tttccttcct tatcactgac     3840

acaaaaagta gattaagaga tgggtttgac aaggttcttc ccttttacat actgctgtct     3900

atgtggctgt atcttgtttt tccactactg ctaccacaac tatattatca tgcaaatgct     3960

gtattcttct ttggtggaga taaagatttc ttgagttttg ttttaaaatt aaagctaaag     4020

tatctgtatt gcattaaata taatatgcac acagtgcttt ccgtggcact gcatacaatc     4080

tgaggcctcc tctctcagtt tttatataga tggcgagaac ctaagtttca gttgatttta     4140

caattgaaat gactaaaaaa caaagaagac aacattaaaa caatattgtt tctaattgct     4200

gaggtttagc tgtcagttct ttttgccctt tgggaattcg gcatggtttc attttactgc     4260

actagccaag agactttact tttaagaagt attaaaattc taaaattcaa aaaaaaaaaa     4320

aaaaaa                                                                4326


<210>  1204
<211>  8106
<212>  DNA
<213>  homo sapiens

<400>  1204
gggagccgcc gtccggccca gctcggcccc agtgagccga gcgctgcgct ccgccgaggg       60

gcagggcggt cgcctgagcg agcgcgggcc cgggacgtcg gcaccggcgg ggcggccgaa      120

ggagaaggag gaagaggaga aggcggcgcg cgggtccccg cgggtcagcc atggcgcgcc      180

ggccccgggg cccccgcacc gccccatagc gccgcggcgt ccgctcggtc tgggccgggc      240

cctgggccct ccagccatgg agccgcacgt gctcggcgcg gtcctgtact ggctgctgct      300

gccctgcgcg ctgctggctg cctgcctgct ccgcttcagc ggactctcgc tggtctacct      360

gctcttcctg ctgctgctgc cctggttccc cggccccacc cgatgcggcc tccaaggtca      420

cacaggccgc ctcctgcggg cattgctggg cctcagcctg ctcttcctgg tggcccatct      480

cgccctccag atctgcctgc atattgtgcc ccgcctggac cagctcctgg gacccagctg      540

cagccgctgg gagaccctct cgcgacacat aggggtcaca aggctggacc tgaaggacat      600

ccccaacgcc atccggctgg tggcccctga cctgggcatc ttggtggtct cctctgtctg      660

cctcggcatc tgcgggcgcc ttgcaaggaa cacccggcag agcccacatc cacgggagct      720

ggatgatgat gagagggatg tggatgccag cccgacggca gggctgcagg aagcagcaac      780

gctggcccct acacggaggt cacggctggc cgctcgtttc cgagtcacgg cccactggct      840

gctggtggcg gctgggcggg tcctggccgt aacactgctt gcactggcag gcatcgccca      900

cccctcggcc ctctccagtg tctacctgct gctcttcctg gccctctgca cctggtgggc      960

ctgccacttt cccatcagca ctcggggctt cagcagactc tgcgtcgcgg tggggtgctt     1020

cggcgccggc catctcatct gcctctactg ctaccagatg cccttggcac aggctctgct     1080

cccgcctgcc ggcatctggg ctagggtgct gggtctcaag gacttcgtgg gtcccaccaa     1140

ctgctccagc ccccacgcgc tggtcctcaa caccggcctg gactggcctg tgtatgccag     1200

ccccggcgtc ctcctgctgc tgtgctacgc cacggcctct ctgcgcaagc tccgcgcgta     1260

ccgcccctcc ggccagagga aggaggcggc aaaggggtat gaggctcggg agctggagct     1320

agcagagctg gaccagtggc cccaggaacg ggagtctgac cagcacgtgg tgcccacagc     1380

acccgacacc gaggctgata actgcatcgt gcacgagctg accggccaga gctccgtcct     1440

gcggcggcct gtgcggccca agcgggctga gcccagggag gcgtctccgc tccacagcct     1500

gggccacctc atcatggacc agagctatgt gtgcgcgctc attgccatga tggtatggag     1560

catcacctac cacagctggc tgaccttcgt actgctgctc tgggcctgcc tcatctggac     1620

ggtgcgcagc cgccaccaac tggccatgct gtgctcgccc tgcatcctgc tgtatgggat     1680

gacgctgtgc tgcctacgct acgtgtgggc catggacctg cgccctgagc tgcccaccac     1740

cctgggcccc gtcagcctgc gccagctggg gctggagcac acccgctacc cctgtctgga     1800

ccttggtgcc atgttgctct acaccctgac cttctggctc ctgctgcgcc agtttgtgaa     1860

agagaagctg ctgaagtggg cagagtctcc agctgcgctg acggaggtca ccgtggcaga     1920

cacagagccc acgcggacgc agacgctgtt gcagagcctg ggggagctgg tgaagggcgt     1980

gtacgccaag tactggatct atgtgtgtgc tggcatgttc atcgtggtca gcttcgccgg     2040

ccgcctcgtg gtctacaaga ttgtctacat gttcctcttc ctgctctgcc tcaccctctt     2100

ccaggtctac tacagcctgt ggcggaagct gctcaaggcc ttctggtggc tcgtggtggc     2160

ctacaccatg ctggtcctca tcgccgtcta caccttccag ttccaggact tccctgccta     2220

ctggcgcaac ctcactggct tcaccgacga gcagctgggg gacctgggcc tggagcagtt     2280

cagcgtgtcc gagctcttct ccagcatcct ggtgcccggc ttcttcctcc tggcctgcat     2340

cctgcagctg cactacttcc acaggccctt catgcagctc accgacatgg agcacgtgtc     2400

cctgcctggc acgcgcctcc cgcgctgggc tcacaggcag gatgcagtga gtgggacccc     2460

actgctgcgg gaggagcagc aggagcatca gcagcagcag caggaggagg aggaggagga     2520

ggaggactcc agggacgagg ggctgggcgt ggccactccc caccaggcca cgcaggtgcc     2580

tgaaggggca gccaagtggg gcctggtggc tgagcggctg ctggagctgg cagccggctt     2640

ctcggacgtc ctctcacgcg tgcaggtgtt cctgcggcgg ctgctggagc ttcacgtttt     2700

caagctggtg gccctgtaca ccgtctgggt ggccctgaag gaggtgtcgg tgatgaacct     2760

gctgctggtg gtgctgtggg ccttcgccct gccctaccca cgcttccggc ccatggcctc     2820

ctgcctgtcc accgtgtgga cctgcgtcat catcgtgtgt aagatgctgt accagctcaa     2880

ggttgtcaac ccccaggagt attccagcaa ctgcaccgag cccttcccca acagcaccaa     2940

cttgctgccc acggagatca gccagtccct gctgtaccgg gggcccgtgg accctgccaa     3000

ctggtttggg gtgcggaaag ggttccccaa cctgggctac atccagaacc acctgcaagt     3060

gctgctgctg ctggtattcg aggccatcgt gtaccggcgc caggagcact accgccggca     3120

gcaccagctg gccccgctgc ctgcccaggc cgtgtttgcc agcggcaccc gccagcagct     3180

ggaccaggat ctgctcggct gcctcaagta cttcatcaac ttcttcttct acaaattcgg     3240

gctggagatc tgcttcctga tggccgtgaa cgtgatcggg cagcgcatga actttctggt     3300

gaccctgcac ggttgctggc tggtggccat cctcacccgc aggcaccgcc aggccattgc     3360

ccgcctctgg cccaactact gcctcttcct ggcgctgttc ctgctgtacc agtacctgct     3420

gtgcctgggg atgcccccgg ccctgtgcat tgattatccc tggcgctgga gccgggccgt     3480

ccccatgaac tccgcactca tcaagtggct gtacctgcct gatttcttcc gggcccccaa     3540

ctccaccaac ctcatcagcg actttctcct gctgctgtgc gcctcccagc agtggcaggt     3600

gttctcagct gagcgcacag aggagtggca gcgcatggct ggcgtcaaca ccgaccgcct     3660

ggagccgctg cggggggagc ccaaccccgt gcccaacttt atccactgca ggtcctacct     3720

tgacatgctg aaggtggccg tcttccgata cctgttctgg ctggtgctgg tggtggtgtt     3780

tgtcacgggg gccacccgca tcagcatctt cgggctgggc tacctgctgg cctgcttcta     3840

cctgctgctc ttcggcacgg ccctgctgca gagggacaca cgggcccgcc tcgtgctgtg     3900

ggactgcctc attctgtaca acgtcaccgt catcatctcc aagaacatgc tgtcgctcct     3960

ggcctgcgtc ttcgtggagc agatgcagac cggcttctgc tgggtcatcc agctcttcag     4020

ccttgtatgc accgtcaagg gctactatga ccccaaggag atgatggaca gagaccagga     4080

ctgcctgctg cctgtggagg aggctggcat catctgggac agcgtctgct tcttcttcct     4140

gctgctgcag cgccgcgtct tccttagcca ttactacctg cacgtcaggg ccgacctcca     4200

ggccaccgcc ctgctagcct ccaggggctt cgccctctac aacgctgcca acctcaagag     4260

cattgacttt caccgcagga tagaggagaa gtccctggcc cagctgaaaa gacagatgga     4320

gcgtatccgt gccaagcagg agaagcacag gcagggccgg gtggaccgca gtcgccccca     4380

ggacaccctg ggccccaagg accccggcct ggagccaggg cccgacagtc cagggggctc     4440

ctccccgcca cggaggcagt ggtggcggcc ctggctggac cacgccacag tcatccactc     4500

cggggactac ttcctgtttg agtccgacag tgaggaagag gaggaggctg ttcctgaaga     4560

cccgaggccg tcggcacaga gtgccttcca gctggcgtac caggcatggg tgaccaacgc     4620

ccaggcggtg ctgaggcggc ggcagcagga gcaggagcag gcaaggcagg aacaggcagg     4680

acagctaccc acaggaggtg gtcccagcca ggaggtggag ccagcagagg gccccgagga     4740

ggcagcggca ggccggagcc atgtggtgca gagggtgctg agcacggcgc agttcctgtg     4800

gatgctgggg caggcgctag tggatgagct gacacgctgg ctgcaggagt tcacccggca     4860

ccacggcacc atgagcgacg tgctgcgggc agagcgctac ctcctcacac aggagctcct     4920

gcagggcggc gaagtgcaca ggggcgtgct ggatcagctg tacacaagcc aggccgaggc     4980

cacgctgcca ggccccaccg aggcccccaa tgccccaagc accgtgtcca gtgggctggg     5040

cgcggaggag ccactcagca gcatgacaga cgacatgggc agccccctga gcaccggcta     5100

ccacacgcgc agtggcagtg aggaggcagt caccgacccc ggggagcgtg aggctggtgc     5160

ctctctgtac cagggactga tgcggacggc cagcgagctg ctcctggaca ggcgcctgcg     5220

catcccagag ctggaggagg cagagctgtt tgcggagggg cagggccggg cgctgcggct     5280

gctgcgggcc gtgtaccagt gtgtggccgc ccactcggag ctgctctgct acttcatcat     5340

catcctcaac cacatggtca cggcctccgc cggctcgctg gtgctgcccg tgctcgtctt     5400

cctgtgggcc atgctgtcga tcccgaggcc cagcaagcgc ttctggatga cggccatcgt     5460

cttcaccgag atcgcggtgg tcgtcaagta cctgttccag tttgggttct tcccctggaa     5520

cagccacgtg gtgctgcggc gctacgagaa caagccctac ttcccgcccc gcatcctggg     5580

cctggagaag actgacggct acatcaagta cgacctggtg cagctcatgg cccttttctt     5640

ccaccgctcc cagctgctgt gctatggcct ctgggaccat gaggaggact caccatccaa     5700

ggagcatgac aagagcggcg aggaggagca gggagccgag gaggggccag gggtgcctgc     5760

ggccaccacc gaagaccaca ttcaggtgga agccagggtc ggacccacgg acgggacccc     5820

agaaccccaa gtggagctca ggccccgtga tacgaggcgc atcagtctac gttttagaag     5880

aaggaagaag gagggcccag cacggaaagg agcggcagcc atcgaagctg aggacaggga     5940

ggaagaagag ggggaggaag agaaagaggc ccccacgggg agagagaaga ggccaagccg     6000

ctctggagga agagtaaggg cggccgggcg gcggctgcag ggcttctgcc tgtccctggc     6060

ccagggcaca tatcggccgc tacggcgctt cttccacgac atcctgcaca ccaagtaccg     6120

cgcagccacc gacgtctatg ccctcatgtt cctggctgat gttgtcgact tcatcatcat     6180

catttttggc ttctgggcct ttgggaagca ctcggcggcc acagacatca cgtcctccct     6240

atcagacgac caggtacccg aggctttcct ggtcatgctg ctgatccagt tcagtaccat     6300

ggtggttgac cgcgccctct acctgcgcaa gaccgtgctg ggcaagctgg ccttccaggt     6360

ggcgctggtg ctggccatcc acctatggat gttcttcatc ctgcccgccg tcactgagag     6420

gatgttcaac cagaatgtgg tggcccagct ctggtacttc gtgaagtgca tctacttcgc     6480

cctgtccgcc taccagatcc gctgcggcta ccccacccgc atcctcggca acttcctcac     6540

caagaagtac aatcatctca acctcttcct cttccagggg ttccggctgg tgccgttcct     6600

ggtggagctg cgggcagtga tggactgggt gtggacggac accacgctgt ccctgtccag     6660

ctggatgtgt gtggaggaca tctatgccaa catcttcatc atcaaatgca gccgagagac     6720

agagaagaaa tacccgcagc ccaaagggca gaagaagaag aagatcgtca agtacggcat     6780

gggtggcctc atcatcctct tcctcatcgc catcatctgg ttcccactgc tcttcatgtc     6840

gctggtgcgc tccgtggttg gggttgtcaa ccagcccatc gatgtcaccg tcaccctgaa     6900

gctgggcggc tatgagccgc tgttcaccat gagcgcccag cagccgtcca tcatcccctt     6960

cacggcccag gcctatgagg agctgtcccg gcagtttgac ccccagccgc tggccatgca     7020

gttcatcagc cagtacagcc ctgaggacat cgtcacggcg cagattgagg gcagctccgg     7080

ggcgctgtgg cgcatcagtc cccccagccg tgcccagatg aagcgggagc tctacaacgg     7140

cacggccgac atcaccctgc gcttcacctg gaacttccag agggacctgg cgaagggagg     7200

cactgtggag tatgccaacg agaagcacat gctggccctg gcccccaaca gcactgcacg     7260

gcggcagctg gccagcctgc tcgagggcac ctcggaccag tctgtggtca tccctaatct     7320

cttccccaag tacatccgtg cccccaacgg gcccgaagcc aaccctgtga agcagctgca     7380

gcccaatgag gaggccgact acctcggcgt gcgtatccag ctgcggaggg agcagggtgc     7440

gggggccacc ggcttcctcg aatggtgggt catcgagctg caggagtgcc ggaccgactg     7500

caacctgctg cccatggtca ttttcagtga caaggtcagc ccaccgagcc tcggcttcct     7560

ggctggctac ggcatcatgg ggctgtacgt gtccatcgtg ctggtcatcg gcaagttcgt     7620

gcgcggattc ttcagcgaga tctcgcactc cattatgttc gaggagctgc cgtgcgtgga     7680

ccgcatcctc aagctctgcc aggacatctt cctggtgcgg gagactcggg agctggagct     7740

ggaggaggag ttgtacgcca agctcatctt cctctaccgc tcaccggaga ccatgatcaa     7800

gtggactcgt gagaaggagt aggagctgct gctggcgccc gagagggaag gagccggcct     7860

gctgggcagc gtggccacaa ggggcggcac tcctcaggcc gggggagcca ctgccccgtc     7920

caaggccgcc agctgtgatg catcctcccg gcctgcctga gccctgatgc tgctgtcaga     7980

gaaggacact gcgtccccac ggcctgcgtg gcgctgccgt cccccacgtg tactgtagag     8040

tttttttttt aattaaaaaa tgttttattt atacaaatgg acaatcagaa aaaaaaaaaa     8100

aaaaaa                                                                8106


<210>  1205
<211>  1563
<212>  DNA
<213>  homo sapiens

<400>  1205
cgcagagttt caaatcggct gcggtgggcg aggagcagct gtgctgcggc tgtgctcggc       60

cttagtggtg tcggggtcta gtggacagag aagactcttg gccaggcaga tggcttctcg      120

gtggcagaac atggggacct ccgtgcgccg gagatctctc cagcaccagg agcagctgga      180

ggacagcaag gagctgcagc ctgtggtcag ccatcaggag acctctgtag gggccctggg      240

gtccctgtgc agacagttcc aaaggaggct gcccctgaga gccgtcaacc tcaacctccg      300

cgcagggccc tcctggaaac gcctggaaac cccagagcca ggtcagcagg gcctccaggc      360

tgcagctcgc tcagctaaga gtgctttggg tgccgtgtcc cagagaatcc aggagtcctg      420

ccaaagtggc accaagtggc tggtggagac ccaggtgaag gccaggaggc ggaagagagg      480

agcacagaag ggcagtggat ccccaactca cagcctgagc cagaagagca cccggctgtc      540

tggagccgcc cctgcccact cagccgcaga cccctgggag aaggagcatc accgcctctc      600

tgtccggatg ggctcacatg cccacccatt acggcgatca aggcgggagg ctgccttccg      660

gagcccctac tcctcaacag agcccctctg ctctcccagc gagtctgaca gtgacctaga      720

gcctgtgggg gcgggaattc agcatctcca gaagctgtcc caagagctag atgaagccat      780

tatggcggaa gagagtggtg acatcgtctc tctcattcat gactgaggaa gtgcctgcag      840

gaaacaagcc ctgtctgacc gccaaggctt catactcaag gatgtctatg cttccccgtg      900

agcttcctgg aaaaaacccc cgggagtcgt cagtacccct gggccactgc taacaagcac      960

ctaacaaggg gcccagagcc ccctgctcca gccacatctg gacccatcag tgactgcctg     1020

ccatagcctg agagtgtctt ggggagacct tgcagagggg gagaattgtt ccttctgctt     1080

tcctagggga ctcttgagct tagaaactca tcgtacactt gaccttgagc cttctatttg     1140

cctcatctat aacatgaagt gctagcatca gatatttgag agctcttagc tctgtacccg     1200

ggtgcctggt ttttggggag tcatccgcag agtcactcac ccactgtgtt tctggtgcca     1260

aggctcttga gggccccact ctcatccctc ctttccctac cagggactcg gaggaaggca     1320

taggagatat ttccaggctt acgaccctgg gctcacgggt acctatttat atgctcagtg     1380

cagagcactg tggatgtgcc aggaggggta gccctgttca agagcaattt ctgccctttg     1440

taaattattt aagaaacctg ctttgtcatt ttattagaaa gaaaccagcg tgtgactttc     1500

ctagataaca ctgctttctc ataataaaga ctatttgcat ttgaaaaaaa aaaaaaaaaa     1560

aaa                                                                   1563


<210>  1206
<211>  5441
<212>  DNA
<213>  homo sapiens

<400>  1206
cttctcagat cctttgcggg tagccctggc gtcccgcgga gaccccaccc cctggctacc       60

tgagtgaaga tggagaaacc agtgaccacc agatgaacca cagcatggac gcaggttctc      120

caaacctatc cccgaatccg atgtccccag cacataataa cttggacctg cagccagtta      180

cctactgcga gccggccttc tggtgctcca tctcctacta cgagctgaac cagcgcgtcg      240

gggagacatt ccacgcctcg cagccatcca tgactgtgga tggcttcacc gacccctcca      300

attcggagcg cttctgccta gggctgctct ccaatgtcaa caggaatgca gcagtggagc      360

tgacacggag acacatcgga agaggcgtgc ggctctacta catcggaggg gaggtcttcg      420

cagagtgcct cagtgacagc gctatttttg tccagtctcc caactgtaac cagcgctatg      480

gctggcaccc ggccaccgtc tgcaagatcc caccaggatg caacctgaag atcttcaaca      540

accaggagtt cgctgccctc ctggcccagt cggtcaacca gggctttgag gctgtctacc      600

agttgacccg aatgtgcacc atccgcatga gcttcgtcaa aggctgggga gcggagtaca      660

ggagacagac tgtgaccagt accccctgct ggattgagct gcacctgaat gggcctttgc      720

agtggcttga caaggtcctc acccagatgg gctccccaag catccgctgt tccagtgtgt      780

cttagagaca tcaagtatgg taggggaggg caggcttggg gaaaatggcc atgcaggagg      840

tggagaaaat tggaactcta ctcaacccat tgttgtcaag gaagaagaaa tctttctccc      900

tcaactgaag gggtgcaccc acctgttttc tgaaacacac gagcaaaccc agaggtggat      960

gttatgaaca gctgtgtctg ccaaacacat ttaccctttg gccccacttt gaagggcaag     1020

aaatggcgtc tgctctggtg gcttaagtga gcagaacagg tagtattaca ccaccggccc     1080

cctcccccca gactcttttt ttgagtgaca gctttctggg atgtcacagt ccaaccagaa     1140

acacccctct gtctaggact gcagtgtgga gttcaccttg gaagggcgtt ctaggtagga     1200

agagcccgca gggccatgca gacctcatgc ccagctctct gacgcttgtg acagtgcctc     1260

ttccagtgaa cattcccagc ccagccccgc cccgccccgc cccaccactc cagcagacct     1320

tgccccttgt gagctggata gacttgggat ggggagggag ggagttttgt ctgtctccct     1380

cccctctcag aacatactga ttgggaggtg cgtgttcagc agaacctgca cacaggacag     1440

cgggaaaaat cgatgagcgc cacctcttta aaaactcact tacgtttgtc ctttttcact     1500

ttgaaaagtt ggaaggatct gctgaggccc agtgcatatg caatgtatag tgtctattat     1560

cacattaatc tcaaagagat tcgaatgacg gtaagtgttc tcatgaagca ggaggccctt     1620

gtcgtgggat ggcatttggt ctcaggcagc accacactgg gtgcgtctcc agtcatctgt     1680

aagagcttgc tccagattct gatgcatacg gctatattgg tttatgtagt cagttgcatt     1740

cattaaatca actttatcat atgctctttt aaatgtttgg tttatatatt ttctttaaaa     1800

atcctgggct ggcacattga ctgggaaacc tgagtgagac ccagcaactg cttctctccc     1860

ttctctctcc tgaggtgaag cttttccagg ttttgttgaa gagatacctg ccagcacttc     1920

tgcaagctga aatttacaga agcaaattca ccagaaggga aacatctcag gccaacatag     1980

gcaaatgaaa agggctatta aaatattttt acacctttga aaattgcagg cttggtacaa     2040

agaggtctgt catcttcccc ctgggatata agatgatcta gctcccggta gaggatcacc     2100

ggtgacaact atagcagttg tattgtgtaa caagtactgc tcccagcagc aattagggag     2160

aaaactagtc taaattattt caactggaaa aaagaaaaaa gagtcctctt cttttcccag     2220

ccttttgcag aacacagtag acagaactgc caccttcaat tggtacttta ttctttgctg     2280

ctgtttttgt ataaaatgac ctatcccacg tttttgcatg aatttatagc aggaaaaatc     2340

aagggatttc ctatggaagt cctgctttat tccaggtgaa gggaaggaag tgtatatact     2400

tttggcaagt catacagctc aaatgtgatg agatttctga tgttagaggg agatggagag     2460

gcttcctgat gcctcatctg cagggtcctg tgcctctgaa gttctagcca tgaggtttcc     2520

aggtaggaca gctgctcccc aagcctcctg aggacacagg aagagacgga aggagcacct     2580

tgacagactt gtgtgagtct tctcgaagga gggttgactc agaacccaga gacaatacaa     2640

aacccctcac ttcctctgag agggccaaat gctgtgagtc tgaagtatgt gcctggtgtg     2700

aaatgatcta tggcctgttt cttacacagg aagccccctg aacctcctgt acatgtgttc     2760

atgttcccag ccagctctga gacccaggaa ccaaatattc cattttggct tctgctagag     2820

cagtcatggt tcctctccta aaagccatgg gcagcagttt ccgagggcct gcatgatcca     2880

cctgctgcac gatcctatga gggcttcctg tggcacacag ccctctgggt gcttgggaac     2940

tagcttcagg cacagcctga ttctggtgat ccagtgatct atggaagtcg tgtcttactc     3000

caggtgaagg gggaaaaaaa aagcctatac tttggcaggt tatgaacttt gaatgtgatg     3060

aaatgacacg tttggctgca tttggatggt gtcttagaac cctcattgct cagacctgaa     3120

ggctacttct aggagcatga agtttgagtt ttgtgttttt ccaaaggata cttccttggc     3180

cctttttctt tattgactag accaccagag gaggatgtgt gggattgtag gcaaacccac     3240

ctgtggcatc actgaaaata aatttgatca tacctaagag gttaggaaat ggtgccattc     3300

ccaccttaga gtgctacata ggtgctttgg gcgtatgtaa cattagtgtc cttccttgaa     3360

gccacaagct agttttctta gttttaaaat cctgttgtat gaatggcatt tgtatattaa     3420

aacacttttt taaaggacag ttgaaaaggg caagaggaaa ccagggcagt tctagaggag     3480

tgctggtgac tggatagcag ttttaagtgg cgttcaccta gtcaacacga ccgcgtgtgt     3540

tgcccctgcc ctgggctccc cgccatgaca tcttcacctt gcagcttgtg ctgagactga     3600

cccaagtgca gctagcactg ggacacagat ccttgtcttc agcaccttcc aaggagccaa     3660

cttttattcc ctttcctctc tcccctcccc acctcgcttc ttcccaattt agtaacttag     3720

atgcttccag cacatacgta ggtagctacc ccagccggtt tggattacag gcctgtgctg     3780

gaacatcatc tcagttggcc accttcctgg caggctgtag acctgacatt ttgagacaag     3840

cctagagtca ggagcaggga ctttgactct taggaagagc acacatgagg gcaaggctgc     3900

tggcagacgt ctccattgtc cttatgttgt ctgtgttgta tttttttttt tttattgacc     3960

atggtgatta tttttttaaa ccatcgttaa tatactgaag tgagctatag cacatatcat     4020

gtgcttagtt tgtttatttt tctccatctc cccttggctt cctagagttt ggacatattc     4080

caggctaaat gcttttactc aagactacag aaaggtttga agtagtgtgt gcatggcatg     4140

cacgtatgta agtaatctgg ggaagaagca aagatctgtt tcattcttag cctcaggcct     4200

catgagggtc tccacagggc cggagctcag gttacaccac tccttcgtcc ttacaggaga     4260

tgtagggaga agaatctgca ggctgcttgt aggactgttc accaaggggg ataccagcag     4320

caagagagtg cacccgttta gccctggacc ctgtttctta ctgtgtgact tggctagagt     4380

tgggagttcc cccaaaataa acgtgtcccc attttaccag aaccaaacct caacacagcg     4440

aagctgtact gtctttgtgt ggcaaagatg ttcccttgta ggcccctttc aggtaaccgt     4500

cttcacaatg tattttcatc acagtttaag gagcatcagc cgcttctcaa gtgggtaggg     4560

aaagcagaaa aacgtacgca agaggacatg gatccaaaat gatgatgaag catctcccat     4620

ggggaggtga tggtggggag atgatgggct aaacaggcaa cttttcaaaa acacagctat     4680

catagaaaag aaacttgcct catgtaaact ggattgagaa attctcagtg attctgcaat     4740

ggattttttt ttaatgcaga agtaatgtat actctagtat tctggtgttt ttatatttat     4800

gtaataattt cttaaaacca ttcagacaga taactattta atttttttta agaaagttgg     4860

aaaggtctct cctcccaagg acagtggctg gaagagttgg ggcacagcca gttctgaatg     4920

ttggtggagg gtgtagtggc tttttggctc agcatccaga aacaccaaac caggctggct     4980

aaacaagtgg ccgcgtgtaa aaacagacag ctctgagtca aatctgggcc cttccacaag     5040

ggtcctctga accaagcccc actcccttgc taggggtgaa agcattacag agagatggag     5100

ccatctatcc aagaagcctt cactcacctt cactgctgct gttgcaactc ggctgttctg     5160

gactctgatg tgtgtggagg gatggggaat agaacattga ctgtgttgat taccttcact     5220

attcggccag cctgaccttt taataacttt gtaaaaagca tgtatgtatt tatagtgttt     5280

tagatttttc taacttttat atcttaaaag cagagcacct gtttaagcat tgtaccccta     5340

ttgttaaaga tttgtgtcct ctcattccct ctcttcctct tgtaagtgcc cttctaataa     5400

acttttcatg gaaaagctcc tgtgccagga gctcagtctg a                         5441


<210>  1207
<211>  4769
<212>  DNA
<213>  homo sapiens

<400>  1207
agaacgtcag ccagtaagcg ccgttcctcc gggagatgtg gaggaggggg gcggcgtgga       60

ggaagagggg gaagttggcg catgcgccta aagctgacgg gtttgaaatg gcttcgatgt      120

tagccgggac ccgactcaga tcgatgctat agaagacaaa caagggaagg ttttttttcc      180

ttttgcatca tggctcaatt tggaggacag aagaatccgc catgggctac tcagtttaca      240

gccactgcag tatcacagcc agctgcactg ggtgttcaac agccatcact ccttggagca      300

tctcctacca tttatacaca gcaaactgca ttggcagcag caggccttac cacacaaact      360

ccagcaaact atcagttaac acaaactgct gcattgcagc aacaagccgc agctgcagca      420

gctgcattac aacagcaata ttcacaacct cagcaggccc tgtatagtgt gcaacaacag      480

ttacagcaac cccagcaaac cctcttaaca cagccagctg ttgcactgcc tacaagcctt      540

agcctgtcta ctcctcagcc aacagcacaa ataactgtat catatccaac accaaggtcc      600

agtcaacagc aaacccagcc tcagaagcag cgtgttttca caggggtggt tacaaaacta      660

catgatacgt ttggatttgt ggatgaagat gtattctttc agcttagtgc tgtcaaaggg      720

aaaacccccc aagtaggtga cagagtattg gttgaagcta cttataatcc taatatgcct      780

tttaaatgga atgcacagag aattcaaaca ctaccaaatc agaatcagtc gcaaacccag      840

ccattactga agactcctcc tgctgtactt cagccaattg caccacagac aacatttggt      900

gttcagactc agccccagcc ccagtcactg ctgcaggcac agatttcagc agcttctatt      960

acaccactat tgcagactca accacagccc ttattacagc agcctcagca aaaagctggt     1020

ttattgcagc ctcctgttcg tatagtttca cagccacaac cggcacgacg attagatccc     1080

ccatcccgat tttcaggaag aaatgacaga ggggatcaag tgcctaacag aaaagatgat     1140

cgaagtcgtg agagagagag agaaagacgt agatcgagag aaagatcacc tcagaggaaa     1200

cgttcccggg aaagatctcc acgaagagag cgagagcgat cacctcggag agttcgacgt     1260

gttgttccac gttacacagt tcagttttca aagttttctt tagattgtcc cagttgtgac     1320

atgatggaac taaggcgccg ttatcaaaat ttgtatatac ctagtgactt ttttgatgct     1380

caatttacat gggtggatgc tttccctttg tcaagaccat ttcagctggg aaattactgc     1440

aatttttatg taatgcacag agaagtagag tccttagaaa aaaatatggc cattcttgat     1500

ccaccagatg ctgaccactt atacagtgca aaggtaatgc tgatggctag ccctagtatg     1560

gaagatttat atcataagtc atgtgctctt gctgaggacc cacaagaact tcgagatgga     1620

ttccaacatc ctgctagact tgttaagttt ttagtgggca tgaaaggcaa ggatgaagct     1680

atggccattg gaggccactg gtctccttcg ttggatggac cagacccaga aaaagatccc     1740

tctgtgttga ttaagactgc tattcgttgt tgtaaggctc tgacaggcat tgatctaagt     1800

gtgtgcacac aatggtaccg ttttgcagag attcgctacc atcgccctga ggagacccac     1860

aaggggcgta cagttccagc tcatgtggag acagtggttt tatttttccc ggatgtttgg     1920

cattgccttc ccacccgctc agagtgggaa accctctccc gaggatacaa gcagcagctg     1980

gtcgagaagc ttcagggtga acgcaaggag gctgatggag aacaggatga agaagagaag     2040

gatgatggtg aagctaaaga aatttctaca cctacccatt ggtctaaact tgatccaaag     2100

acaatgaagg taaatgacct ccgaaaagaa ttagaaagtc gagctcttag ttccaaagga     2160

ttaaaatccc agttaatagc ccgattgaca aaacagctta aagtagagga acaaaaagaa     2220

gaacagaagg agttagagaa atctgaaaaa gaagaggatg aggatgatga taggaaatct     2280

gaagacgata aagaggaaga agaaaggaaa cgtcaagagg aaatagaacg ccagcgtcga     2340

gaaagaagat atattttgcc tgatgaaccg gccatcattg tacatccaaa ttgggctgca     2400

aaaagtggca agtttgattg tagcatcatg tctttgagtg tcctattgga ctacagatta     2460

gaggataata aagaacattc atttgaggtt tcattgtttg cggaactttt caacgaaatg     2520

cttcaaagag attttggtgt ccgtatatac aaatcattac tgtctcttcc tgagaaagag     2580

gacaaaaaag aaaaggataa aaaaagcaaa aaagatgaga gaaaagataa aaaagaagaa     2640

agagatgatg aaactgatga accaaaaccc aaacggagaa aatcaggcga tgataaagat     2700

aaaaaagaag atagagatga aaggaagaaa gaagataaaa gaaaagatga ttctaaagat     2760

gatgatgaaa ctgaagaaga taacaatcaa gatgaatatg accctatgga agcagaagaa     2820

gctgaggatg aagaagatga tagggatgag gaagaaatga ccaaacgaga tgacaaaaga     2880

gatatcaaca gatactgcaa ggagaggccc tctaaagata aggaaaaaga aaagactcaa     2940

atgatcacaa ttaacagaga tctgttaatg gcttttgttt attttgatca aagtcattgt     3000

ggttaccttc ttgaaaagga tttggaagaa atactttata ctcttggact acatctttct     3060

cgggctcagg taaagaagct tcttaataaa gtagtgctcc gtgaatcttg cttttaccgg     3120

aaattaacag acacctcaaa agatgaagag aaccatgaag agtctgagtc attgcaggaa     3180

gatatgctag gaaacagatt attacttcca acaccaacag taaagcagga atcaaaggat     3240

gtggaagaaa atgttggcct cattgtgtac aatggtgcaa tggtagatgt aggaagcctc     3300

ttgcaaaaat tggaaaagag cgaaaaagta agagctgagg tagaacagaa gctgcagtta     3360

ctagaagaaa aaacagatga agatgaaaaa accatattaa atttggagaa ttccaacaaa     3420

agcctctctg gtgaactcag agaagttaaa aaggacctta gtcagttaca agaaaactta     3480

aagatttcgg aaaacatgaa tttacaattt gaaaaccaaa tgaataagac aatcagaaac     3540

ttatctacgg taatggatga aatccacact gttctcaaga aggataatgt aaagaatgaa     3600

gacaaagatc aaaaatccaa ggagaatggt gccagtgtat gataaaatcc atgtagtgat     3660

gaggaatggt gttaaataat gtaatatata aaaatcatga tataagaatg tttgaaggtg     3720

atgcatgttt gattttagta gtataaatgt attttagttc aaatgatgta taaagtttta     3780

tgaatgtgag tttctgcttt tgaaaattgc ttgtaattcc tagccttcaa attattaaac     3840

actccttgag tgaaataatt ttgcattgca aagtgtttta ggatgaactt tgttatagtt     3900

ttaactccaa taaagttcat cagtttaatt gactgtagta tttaattacc aaatttcttt     3960

tattaaaatg cctagaaatt tttaatttat agaattatta ggttttaaaa tttttagttc     4020

atctgttaaa atttcagtca aaatcataaa atagcatgat gcttaatttt tgcaagtttt     4080

ttgaaacttt ttgttttttt tactcatcac caaaaaatcc cctcttgatc agtctctaaa     4140

agcattcatt aaaaattcag ttcaggccgg gcacggtggc tcacacctgt aatcccaaca     4200

ctttgggagg ccgaggcagg tggatcacct gaggttagga gttcgagacc agcctggcca     4260

acatggtgaa acccggtctc tactaaaaat ataaaaatta gctgggcatg gtggtgggtg     4320

cctgtaatcc cagctacttg ggaggctgag gcaggagaat cgcttgaacc caggaggcgg     4380

aggttgcagt cactcaggat catgcagcta cactccagcc tgggcgacaa gagtgaaact     4440

ccatctcaaa aagaaaaaaa aaaaaaatca gtttatttga aagacagtat atcagaaaga     4500

aagaagcaat agagaactag tattgttctt tatgggttag actttacata atattagttg     4560

tcctgatgtc aatgttactg ctttcaatta atttttctac tttcccagaa tagcatctat     4620

attcctttta attttgaggg tttaaaaaaa aatgcagtgt atgtcaaatt tacagtttag     4680

taccaagcca gtagatgtca gtatgatgcc ttaaattaag tcttctttaa ttaaagatat     4740

ttttttaaat taaaaaaaaa aaaaaaaaa                                       4769


<210>  1208
<211>  1324
<212>  DNA
<213>  homo sapiens

<400>  1208
ttcacttccg ggccgcggtc tagggcggct acgtgtgttg ccatagcgac cattttgcat       60

taactggttg gtagcttcta tcctgggggc tgagcgactg cgggccagct cttcccctac      120

tccctctcgg ctccttgtgg cccaaaggcc taaccggggt ccggcggtct ggcctaggga      180

tcttccccgt tgcccctttg gggcgggatg gctgcggaag aagaagacga ggtggagtgg      240

gtagtggaga gcatcgcggg gttcctgcga ggcccagact ggtccatccc catcttggac      300

tttgtggaac agaaatgtga agtttttgat gatgaagaag aaagcaaatt gacctataca      360

gagattcatc aggaatacaa agaactagtt gaaaagctgt tagaaggtta cctcaaagaa      420

attggaatta atgaagatca atttcaagaa gcatgcactt ctcctcttgc aaagacccat      480

acatcacagg ccattttgca acctgtgttg gcagcagaag attttactat ctttaaagca      540

atgatggtcc agaaaaacat tgaaatgcag ctgcaagcca ttcgaataat tcaagagaga      600

aatggtgtat tacctgactg cttaaccgat ggctctgatg tggtcagtga ccttgaacac      660

gaagagatga aaatcctgag ggaagttctt agaaaatcaa aagaggaata tgaccaggaa      720

gaagaaagga agaggaaaaa acagttatca gaggctaaaa cagaagagcc cacagtgcat      780

tccagtgaag ctgcaataat gaataattcc caaggggatg gtgaacattt tgcacaccca      840

ccctcagaag ttaaaatgca ttttgctaat cagtcaatag aacctttggg aagaaaagtg      900

gaaaggtctg aaacttcctc cctcccacaa aaagacctga agattcctgg cttagagcat      960

gcgagcattg aaggaccaat agcaaactta tcagtacttg gaacagaaga acttcggcaa     1020

cgagaacact atctcaagca gaagagagat aagttgatgt ccatgagaaa ggatatgagg     1080

actaaacaga tacaaaatat ggagcagaaa ggaaaaccca ctggggaggt agaggaaatg     1140

acagagaaac cagaaatgac agcagaggag aagcaaacat tactaaagag gagattgctt     1200

gcagagaaac tcaaagaaga agttattaat aagtaataat taagaacaat ttaacaaaat     1260

ggaagttcaa attgtcttaa aaataaatta tttagtcctt acactgagaa aaaaaaaaaa     1320

aaaa                                                                  1324


<210>  1209
<211>  2643
<212>  DNA
<213>  homo sapiens

<400>  1209
acttgtccgt cacgtgcggc cgcccggcct ctcggccttg ccgcgcgcct ggcggggttg       60

ggggggcggg gaccaagatc tgctgcgcct gcgttgtggg cgttctcggg gagctgctgc      120

cgtagctgcc gccgccgcta ccaccgcgtt cgggtgtaga atttggaatc cctgcgccgc      180

gttaacaatg aagcagagtt cgaacgtgcc ggctttcctc agcaagctgt ggacgcttgt      240

ggaggaaacc cacactaacg agttcatcac ctggagccag aatggccaaa gttttctggt      300

cttggatgag caacgatttg caaaagaaat tcttcccaaa tatttcaagc acaataatat      360

ggcaagcttt gtgaggcaac tgaatatgta tggtttccgt aaagtagtac atatcgactc      420

tggaattgta aagcaagaaa gagatggtcc tgtagaattt cagcatcctt acttcaaaca      480

aggacaggat gacttgttgg agaacattaa aaggaaggtt tcatcttcaa aaccagaaga      540

aaataaaatt cgtcaggaag atttaacaaa aattataagt agtgctcaga aggttcagat      600

aaaacaggaa actattgagt ccaggctttc tgaattaaaa agtgagaatg agtccctttg      660

gaaggaggtg tcagaattac gagcaaagca tgcacaacag caacaagtta ttcgaaagat      720

tgtccagttt attgttacat tggttcaaaa taaccaactt gtgagtttaa aacgtaaaag      780

gcctctactt ctaaacacta atggagccca aaagaagaac ctgtttcagc acatagtcaa      840

agaaccaact gataatcatc atcataaagt tccacacagt aggactgaag gtttaaagcc      900

aagggagagg atttcagatg acatcattat ttatgatgtt actgatgata atgcagatga      960

agaaaatatc ccagttattc cagaaactaa tgaggatgtt atatctgatc cctccaactg     1020

tagccagtac cctgatattg tcatcgttga agatgacaat gaagatgagt atgcacctgt     1080

cattcagagt ggagagcaga atgaaccagc cagagaatcc ctaagttcag gcagtgatgg     1140

cagcagccct ctcatgtcta gtgctgtcca gctaaatggc tcatccagtc tgacctcaga     1200

agatccagtg accatgatgg attccatttt gaatgataac atcaatcttt tgggaaaggt     1260

tgagctgttg gattatcttg acagtattga ctgcagttta gaggacttcc aggccatgct     1320

atcaggaaga caatttagca tagacccaga tctcctggtt gattctgaga ataaaggatt     1380

agaaactacc aagaacaatg tagttcagcc agtttcggaa gagggaagaa aatctaaatc     1440

caaaccagat aagcagctta tccagtatac cgcctttcca cttcttgcat tcctcgatgg     1500

gaaccctgct tcttctgttg aacaggcgag tacaacagca tcatcagaag ttttgtcctc     1560

tgtagataaa cccatagaag ttgatgagct tctggatagc agcctagacc cagaaccaac     1620

ccaaagtaag cttgttcgcc tggagccatt gactgaagct gaagctagtg aagctacact     1680

gttttattta tgtgaacttg ctcctgcacc tctggatagt gatatgccac ttttagatag     1740

ctaaatcccc aggaagtgga ctttacatgt atatattcat caaaatgatg aactatttat     1800

tttaaagtat catttggtac tttttttgta aattgctttg ttttgtttaa tcagatactg     1860

tggaataaaa gcaccttttg cttttctcac taaccacaca ctcttgcaga gctttcaggt     1920

gttactcagc tgcatagtta cgcagatgta atgcacatta ttggcgtatc tttaagttgg     1980

attcaaatgg ccatttttct ccaattttgg taaattggat atcttttttt tacaaatacg     2040

accattaacc tcagttaaat ttttgtttgt tttcctgttt gatgctgtct atttgcattg     2100

agtgtaagtc atttgaacta atggtataac tcctaaagct ttctctgctc cagttatttt     2160

tattaaatat ttttcacttg gcttattttt aaaactggga acataaagtg cctgtatctt     2220

gtaaaacttc atttgtttct tttggttcag agaagttcat ttatgttcaa agacgtttat     2280

tcatgttcaa caggaaagac aaagtgtacg tgaatgctcg ctgtctgata gggttccagc     2340

tccatatata tagaaagatc gggggtggga tgggatggag tgagccccat ccagttagtt     2400

ggactagttt taaataaagg ttttccggtt tgtgtttttt tgaaccatac tgtttagtaa     2460

aataaataca atgaatgttg agtactagtg tctgttatgt gtcttcttta gaggtgacac     2520

tcacatgaaa caattttttc ttctcatagg aagcagtagc tttaaactgt ctgtggttca     2580

ttattctcaa tatgaatcat accaagatat ttgtgcctca tctcgaaaat atattgtata     2640

ttg                                                                   2643


<210>  1210
<211>  2138
<212>  DNA
<213>  homo sapiens

<400>  1210
caatgggctg ggccgcgcgg ccgcgcgcac tcgcacccgc tgcccccgag gccctcctgc       60

actctccccg gcgccgctct ccggccctcg ccctgtccgc cgccaccgcc gccgccgcca      120

gagtcgccat gcagatcccg cgcgccgctc ttctcccgct gctgctgctg ctgctggcgg      180

cgcccgcctc ggcgcagctg tcccgggccg gccgctcggc gcctttggcc gccgggtgcc      240

cagaccgctg cgagccggcg cgctgcccgc cgcagccgga gcactgcgag ggcggccggg      300

cccgggacgc gtgcggctgc tgcgaggtgt gcggcgcgcc cgagggcgcc gcgtgcggcc      360

tgcaggaggg cccgtgcggc gaggggctgc agtgcgtggt gcccttcggg gtgccagcct      420

cggccacggt gcggcggcgc gcgcaggccg gcctctgtgt gtgcgccagc agcgagccgg      480

tgtgcggcag cgacgccaac acctacgcca acctgtgcca gctgcgcgcc gccagccgcc      540

gctccgagag gctgcaccgg ccgccggtca tcgtcctgca gcgcggagcc tgcggccaag      600

ggcaggaaga tcccaacagt ttgcgccata aatataactt tatcgcggac gtggtggaga      660

agatcgcccc tgccgtggtt catatcgaat tgtttcgcaa gcttccgttt tctaaacgag      720

aggtgccggt ggctagtggg tctgggttta ttgtgtcgga agatggactg atcgtgacaa      780

atgcccacgt ggtgaccaac aagcaccggg tcaaagttga gctgaagaac ggtgccactt      840

acgaagccaa aatcaaggat gtggatgaga aagcagacat cgcactcatc aaaattgacc      900

accagggcaa gctgcctgtc ctgctgcttg gccgctcctc agagctgcgg ccgggagagt      960

tcgtggtcgc catcggaagc ccgttttccc ttcaaaacac agtcaccacc gggatcgtga     1020

gcaccaccca gcgaggcggc aaagagctgg ggctccgcaa ctcagacatg gactacatcc     1080

agaccgacgc catcatcaac tatggaaact cgggaggccc gttagtaaac ctggacggtg     1140

aagtgattgg aattaacact ttgaaagtga cagctggaat ctcctttgca atcccatctg     1200

ataagattaa aaagttcctc acggagtccc atgaccgaca ggccaaagga aaagccatca     1260

ccaagaagaa gtatattggt atccgaatga tgtcactcac gtccagcaaa gccaaagagc     1320

tgaaggaccg gcaccgggac ttcccagacg tgatctcagg agcgtatata attgaagtaa     1380

ttcctgatac cccagcagaa gctggtggtc tcaaggaaaa cgacgtcata atcagcatca     1440

atggacagtc cgtggtctcc gccaatgatg tcagcgacgt cattaaaagg gaaagcaccc     1500

tgaacatggt ggtccgcagg ggtaatgaag atatcatgat cacagtgatt cccgaagaaa     1560

ttgacccata ggcagaggca tgagctggac ttcatgtttc cctcaaagac tctcccgtgg     1620

atgacggatg aggactctgg gctgctggaa taggacactc aagacttttg actgccattt     1680

tgtttgttca gtggagactc cctggccaac agaatccttc ttgatagttt gcaggcaaaa     1740

caaatgtaat gttgcagatc cgcaggcaga agctctgccc ttctgtatcc tatgtatgca     1800

gtgtgctttt tcttgccagc ttgggccatt cttgcttaga cagtcagcat ttgtctcctc     1860

ctttaactga gtcatcatct tagtccaact aatgcagtcg atacaatgcg tagatagaag     1920

aagccccacg ggagccagga tgggactggt cgtgtttgtg cttttctcca agtcagcacc     1980

caaaggtcaa tgcacagaga ccccgggtgg gtgagcgctg gcttctcaaa cggccgaagt     2040

tgcctctttt aggaatctct ttggaattgg gagcacgatg actctgagtt tgagctatta     2100

aagtacttct tacacattgc aaaaaaaaaa aaaaaaaa                             2138


<210>  1211
<211>  3817
<212>  DNA
<213>  homo sapiens

<400>  1211
tttttttccc cgcctcccaa ccgtgaggtg ttgggtttgg gggacgctgg cagctgggtt       60

ctcccggttc ccttgggcag gtgcagggtc gggttcaaag cctccggaac gcgttttggc      120

ctgatttgag gaggggggcg gggagggacc tgcggcttgc ggccccgccc ccttctccgg      180

ctcgcagccg accggtaagc ccgcctcctc cctcggccgg ccctggggcc gtgtccgccg      240

ggcaactcca gccgaggcct gggcttctgc ctgcaggtgt ctgcggcgag gcccctaggg      300

tacagcccga tttggcccca tggtgggttt cggggccaac cggcgggctg gccgcctgcc      360

ctctctcgtg ctggtggtgc tgctggtggt gatcgtcgtc ctcgccttca actactggag      420

catctcctcc cgccacgtcc tgcttcagga ggaggtggcc gagctgcagg gccaggtcca      480

gcgcaccgaa gtggcccgcg ggcggctgga aaagcgcaat tcggacctct tgctgttggt      540

ggacacgcac aagaaacaga tcgaccagaa ggaggccgac tacggccgcc tcagcagccg      600

gctgcaggcc agagagggcc tcgggaagag atgcgaggat gacaaggtta aactacagaa      660

caacatatcg tatcagatgg cagacataca tcatttaaag gagcaacttg ctgagcttcg      720

tcaggaattt cttcgacaag aagaccagct tcaggactat aggaagaaca atacttacct      780

tgtgaagagg ttagaatatg aaagttttca gtgtggacag cagatgaagg aattgagagc      840

acagcatgaa gaaaatatta aaaagttagc agaccagttt ttagaggaac aaaagcaaga      900

gacccaaaag attcaatcaa atgatggaaa ggaattggat ataaacaatc aagtagtacc      960

taaaaatatt ccaaaagtag ctgagaatgt tgcagataag aatgaagaac cctcaagcaa     1020

tcatattcca catgggaaag aacaaatcaa aagaggtggt gatgcaggga tgcctggaat     1080

agaagagaat gacctagcaa aagttgatga tcttccccct gctttaagga agcctcctat     1140

ttcagtttct caacatgaaa gtcatcaagc aatctcccat cttccaactg gacaacctct     1200

ctccccaaat atgcctccag attcacacat aaaccacaat ggaaaccccg gtacttcaaa     1260

acagaatcct tccagtcctc ttcagcgttt aattccaggc tcaaacttgg acagtgaacc     1320

cagaattcaa acagatatac taaagcaggc taccaaggac agagtcagtg atttccataa     1380

attgaagcaa aatgatgaag aacgagagct tcaaatggat cctgcagact atggaaagca     1440

acatttcaat gatgtccttt aagtcctaaa ggaatgcttc agaaaaccta aagtgctgta     1500

aaatgaaatc attctacttt gtcctttctg acttttgttg taaagacgaa ttgtatcagt     1560

tgtaaagata cattgagata gaattaagga aaaactttaa tgaaggaatg tacccatgta     1620

catatgtgaa ctttttcata ttgtattatc aaggtataga cttttttggt tatgatacag     1680

ttaagccaaa aacagctaat ctttgcatct aaagcaaact aatgtatatt tcacatttta     1740

ttgagccgac ttatttccac aaatagataa acaggacaaa atagttgtac aggttatatg     1800

tggcatagca taaccacagt aagaacagaa cagatattca gcagaaaact ttttatactc     1860

taattctttt tttttttttt tttgagacag agttttagtc ttgtttccca ggctggagtg     1920

caatggcaca atcttggctc actgcaacct ccgcctcctg ggttcaggca attttcctgc     1980

ctcagcctcc caagtagctg ggattacagg cacccaccac catgcccagc taatttttgt     2040

atttttaata gagagctaat aattgtatat ttaataaaga cgggtttcac catgttggcc     2100

aggctggtct tgaactcctg acctcaggtg atcctcctgc attggcctcc caaagtgctg     2160

gaattccagg catgagccac tgcgcccagt ctacacacta attcttgtta gcccaacagc     2220

tgttctgttc tatctacccc tcatttcacg ctcaaggagt catacctaga atagttacac     2280

acaagaggga aactggaagc caaacactgt acagtattgt gtagaaagtc acctccctac     2340

tccttttatt ttacatgagt gctgatgtgt tttggcagat gagctttcag ctgaggcctg     2400

atggaaattg agataacctg caaagacata acagtattta tgagttatat cttagttctt     2460

gaaattgtgg aatgcatgat tgacaatata tttttaattt ttattttttc aagtaatacc     2520

agtactgttt aactatagcc agaactggct aaaattttta tattttcaga gttgaagttg     2580

gtgaagacat tcatgattta aacaccagat cctgaaaggg gttaaatcta ctttgaaatg     2640

aatctgcaat cagtatttca aagcttttct ggtaatttta gtgatcttat ttgattagac     2700

tttttcagaa gtactaaata aggaatttta acaggttttt attaatgcac agataaatag     2760

aagtacagtg aggtctatag ccattttatt aaaatagctt aaaagtttgt aaaaaaatga     2820

atctttgtaa ttacttaata tgttagttaa gaacccgtca agcttatatt tgctagactt     2880

acaaattatt ttaaatgcat ttatcttttt tgacactatt cagtggaatg tgtaagctag     2940

ctaattcttg ttttctgatt taaagcactt ttaaatctta tcctgccccc taaaaacaaa     3000

aggttttgat cacaagggga aatttaagat tgttaaccct gtttttcaga agggctactg     3060

ttaattgcac ataaacatga aatgtgtttt cccctgtgta ctaacacatt ctaggcaaaa     3120

ttcaaactta tagtggtaaa gaaacaggtt gttcacttgc tgaggtgcaa aaattcttaa     3180

gacttctgtt tgaaattgct caatgactag gaaaagatgt agtagtttac taaaattgtt     3240

tttctaccat atcaaattaa acaattcatg cctttatagg gtcaggccta caatgaatag     3300

gtatggtggt ttcacagaat tttaaaatag agttaaaggg aagtgatgta catttcgggg     3360

gcattagggt agggagatga atcaaaaaat acccctagta atgctttata ttttaatact     3420

gcaaaagctt tacaaatgga aaccatgcaa ttacctgcct tagttctttt gtcataaaaa     3480

caatcacttg gttggttgta ttgtagctat tacttataca gcaacatttc ttcaattagc     3540

agtctagaca ttttataaac agaaatcttg gaccaattga taatatttct gactgtatta     3600

atattttagt gctataaaat actatgtgaa tctcttaaaa atctgacatt ttacagtctg     3660

tattagacat actgttttta taatgtttta cttctgcctt aagatttagg ttttttaaat     3720

gtatttttgc cctgaattaa gtgttaattt gatggaaact ctgcttttaa aatcatcatt     3780

tactgggttc taataaatta aaaattaaac ttgtttc                              3817


<210>  1212
<211>  1515
<212>  DNA
<213>  homo sapiens

<400>  1212
ggctcgggag agaccttgga gcgcgcggga aagagaccaa tataaactgt ggcgggatag       60

ttttcgggtc cttgtccagt gaaacaccct cggctgggaa gtcagttcgt tctctcctct      120

cctctcttct tgtttgaaca tggtgcggac taaagcagac agtgttccag gcacttacag      180

aaaagtggtg gctgctcgag cccccagaaa ggtgcttggt tcttccacct ctgccactaa      240

ttcgacatca gtttcatcga ggaaagctga aaataaatat gcaggaggga accccgtttg      300

cgtgcgccca actcccaagt ggcaaaaagg aattggagaa ttctttaggt tgtcccctaa      360

agattctgaa aaagagaatc agattcctga agaggcagga agcagtggct taggaaaagc      420

aaagagaaaa gcatgtcctt tgcaacctga tcacacaaat gatgaaaaag aatagaactt      480

tctcattcat ctttgaataa cgtctccttg tttaccctgg tattctagaa tgtaaattta      540

cataaatgtg tttgttccaa ttagctttgt tgaacaggca tttaattaaa aaatttaggt      600

ttaaatttag atgttcaaaa gtagttgtga aatttgagaa tttgtaagac taattatggt      660

aacttagctt agtattcaat ataatgcatt gtttggtttc ttttaccaaa ttaagtgtct      720

agttcttgct aaaatcaagt cattgcattg tgttctaatt acaagtatgt tgtatttgag      780

atttgcttag attgttgtac tgctgccatt tttattggtg tttgattatt ggaatggtgc      840

catattgtca ctccttctac ttgctttaaa aagcagagtt agatttttgc acattaaaaa      900

attcagtatt aattaaacat tacttattct accctctttt ttggcaagga ggacaaatac      960

gcaatgttgg aaaaccttgg atggatatct tctctttaaa aaaatgtaaa gataatttgg     1020

tcttgagggt ttaaacggtt gataatgcct ctacaacaac aagaaaaaag ataaaatact     1080

aggatagaat catggtgggc acagtggctt ctcaggaggc tgaggaggga ggtttgcttg     1140

agtccaggag ttggagacca gcccaggcaa catagcgtaa accctatctc taaaacaatt     1200

tttagccggg tgcggtggct cacgcctgta atcccagcac tctgggaggc cgaggcgggt     1260

ggatcatgag gtcaggagat cgagaccatc ctgcctaaca aggtgaaacc ccgtctctac     1320

taaaaataca aaaaattagc cgggcgcggt ggcgggcgcc tgtagtccca gctactcggg     1380

aggctgaggc aggagaatgg cgtgaacccg ggaagtggag cttgcagtga gccgagattg     1440

cgccactgca gtcggcagtc cggcttgggc gacagagcga gactccgtct caaaaaaaaa     1500

aaaaaaaaaa aaaaa                                                      1515


<210>  1213
<211>  6092
<212>  DNA
<213>  homo sapiens

<400>  1213
gagtgttttc agaagtggga atagcaggcg aggtcttgag gcctgaagaa gcaaagcgtc       60

gcttagtcaa tgctgagatg cgtcttgtgg aacagaattt ttgggacatt tgcaggatga      120

gttagatgaa ctccgtgctg agatggaaga gatgagagac agttatttag aggaagatgt      180

ttaccagctg caggaacttc ggcgagaact ggaccgcgct aataaaaact gccgaatcct      240

gcagtaccgt cttcggaaag ccgagcagaa aagcctgaaa gtggctgaga cgggtcaggt      300

ggatggtgag cttattcgaa gcctggagca ggacttgaag gtagccaaag atgtatctgt      360

cagattgcac cacgaactta agacggtgga ggaaaagcgc gctaaagctg aggatgaaaa      420

cgaaactctc cgacagcaga tgattgaagt ggaaatatcc aaacaggccc tccagaatga      480

gctggagaga ctgaaagaga gttccctaaa aagaagaagc actcgggaaa tgtacaagga      540

gaagaaaacc tttaaccagg atgacagtgc cgatttgagg tgccagctcc agtttgccaa      600

agaggaagcc ttcctgatgc gcaaaaagat ggccaagcta ggaagggaga aggacgagct      660

ggagcaggag ctccagaagt acaagtccct ctatggggat gtggacagtc ccctgcccac      720

gggggaagca ggcgggcccc ccagcacccg ggaggccgag ctgaagctgc ggctaaagct      780

ggtggaggag gaagccaaca tcttgggccg gaagatcgtg gagctggagg tggagaaccg      840

tggcctcaag gcagagatgg aggacatgcg gggccagcag gagcgggagg gcccgggtcg      900

ggaccacgca cccagcattc ctacctcacc cttcggtgac tccctggagt cctccactga      960

gctccgccgc cacctgcagt ttgtagaaga ggaagcggag ttgctccgga ggtccatctc     1020

cgagatcgaa gaccacaacc ggcaactgac ccacgagctc agcaagttta agtttgagcc     1080

tccccgggag ccgggctggc taggagaggg tgcaagtcct ggtgccgggg gtggggcccc     1140

cctgcaggag gagctgaagt cagccaggct gcagatcagc gagctcagcg gcaaggtgct     1200

caaactgcag cacgagaacc acgcgctgct gtccaacatc cagcgctgcg acctggcagc     1260

ccacctgggg ctgcgtgccc ccagtccccg ggacagcgat gccgagagtg atgcgggcaa     1320

gaaggagagt gatggggagg agagccgcct gccccagccc aagcgggaag ggcctgttgg     1380

cggggagagt gactcggagg aaatgtttga gaagacgtcg ggcttcggga gcgggaagcc     1440

atcggaggcc agcgagccat gccccacgga gctcctgaag gcccgggagg actctgagta     1500

cctagtgacc ctaaaacacg aggcccagcg gctagagcgg acggtggagc gcctcatcac     1560

ggacaccgac agcttcctcc atgatgcggg gctgcggggt ggtgcgccct taccggggcc     1620

tggcctccag ggcgaagagg agcagggtga gggggaccag caggagcccc agctgctggg     1680

gaccatcaac gccaagatga aggctttcaa gaaagagctg caggccttcc tggagcaggt     1740

gaaccgcatt ggggatggcc tatccccctt gccccacctc acagagtcct ctagcttcct     1800

ctccactgtg acttccgtgt cccgggactc ccccatcggg aacctgggga aggagctggg     1860

cccagacttg cagtccagac tgaaagagca gctggagtgg cagctcgggc cggcccgagg     1920

ggacgagcgg gagagcctgc gcctccgagc cgcgcgggag ctgcaccgcc gcgcagacgg     1980

ggacaccggg agccacgggc tgggaggcca gacctgcttc agcctggagc tcaggggccc     2040

ccccgtttta cctgagcaga gtgtatccat agaggagcta cagggtcagc tcgtgcaggc     2100

ggccagactg catcaagagg agacagagac atttacaaac aagatccata agatggagga     2160

ggagcacctc tatgccttga ggtggaaaga actggaaatg cacagcctgg ctttgcaaaa     2220

caccctccat gagcgaacct ggagtgatga gaagaatctg atgcagcagg agctccggtc     2280

cttgaagcag aacattttcc tcttctacgt caaactcagg tggctgctga aacactggcg     2340

gcaagggaag cagatggagg aggaaggaga ggagttcact gagggtgaac atccagagac     2400

cctctccagg ctcggggagc ttggagtcca ggggggtcac caggcggatg gcccagacca     2460

cgacagtgac cgaggctgtg gctttccagt gggggagcac tccccacact cccgggtgca     2520

gattggagat cacagcttgc ggctgcagac cgcggacagg ggacagcccc acaaacaggt     2580

ggtggaaaac cagcagctgt tcagcgcctt caaggccttg ctggaggact tccgtgcgga     2640

gctgcgggag gatgagcgtg cccgactacg gctgcagcag caatatgcca gcgacaaggc     2700

ggcctgggac gtggagtggg ccgtgctcaa gtgccgtctg gaacagctgg aagagaagac     2760

tgagaacaag ttgggagaac taggctcctc cgctgagagc aagggggcct tgaagaagga     2820

gagagaggtg caccagaagc tcctggcaga cagtcacagc ctggtcatgg acctgcgctg     2880

gcagatccat cacagcgaga agaactggaa ccgggagaag gtggaacttc tcgaccgcct     2940

ggacagagat cggcaggagt gggagcggca gaagaaggaa ttcttgtgga ggatagagca     3000

gttgcagaaa gagaacagtc cccggagagg tggcagtttc ctctgtgatc aaaaagacgg     3060

caacgttcgc ccctttcccc accagggaag cctccgcatg ccccgtccag tggccatgtg     3120

gccttgtgca gatgctgact ccatcccgtt tgaagaccgg ccgctgtcca agctgaagga     3180

gtcggacagg tgctcggcca gtgagaatct ctacctggat gccttgtccc tggatgacga     3240

gccagaagag ccaccagccc acaggcccga gagggagttc aggaaccgcc tccctgagga     3300

agaagaaaat cacaaaggaa atcttcaaag ggcggtgtcc gtgtcctcca tgtctgagtt     3360

ccagcgtcta atggacatct cccccttcct gcctgagaag ggcctgccgt ccaccagcag     3420

caaggaggat gtcaccccac ccctgtctcc agacgacctc aagtacatcg aggagttcaa     3480

caagagctgg gactacacac ccaacagggg ccacaatggt ggggggccgg acctttgggc     3540

cgacaggacc gaggtggggc gggcagggca cgaggacagc acagagcctt tccccgactc     3600

ctcctggtac ctaaccacaa gtgtcaccat gaccacggac accatgacca gcccagagca     3660

ctgccagaag cagccactgc ggagccacgt cctcaccgag cagtcggggt tgcgcgtgtt     3720

acacagcccg cctgccgtgc gcagggtcga cagcatcacg gcggcaggtg gtgagggtcc     3780

ctttcccaca agcagagcca gagggagccc gggagacacc aagggaggcc ctccagaacc     3840

catgctcagc aggtggcctt gcacctcccc caggcactcc cgggactatg tggagggggc     3900

acggcgcccc cttgatagtc ccctctgtac ctccctgggg tttgcctccc cactgcacag     3960

cctggagatg tccaagaact tgagtgatga catgaaggag gtggccttct ctgtcaggaa     4020

tgccatctgc tccggccctg gcgagctgca agtcaaggac atggcctgcc agaccaatgg     4080

gtcccggacg atggggaccc agactgttca gaccatcagt gtgggcttgc agactgaagc     4140

cctgcgtggc agcggtgtca ccagcagccc ccacaagtgt ctcactccaa aggctggggg     4200

cggtgctaca cccgtgtcgt ctccttcccg gagccttagg agcagacagg tggcccctgc     4260

catcgagaag gtgcaggcca agtttgaacg cacatgctgc tcccccaagt atggttctcc     4320

caagctgcag aggaagcccc tccccaaagc cgaccagcca aataacagga cgtcaccagg     4380

gatggcccag aaagggtaca gtgagtcagc ctgggcccgc tccaccacca caagggagag     4440

ccccgtgcac accaccatta atgatggcct ctccagcctc ttcaacatca ttgaccacag     4500

ccccgtggtg caggacccct tccagaaggg gctgcgggcc ggcagtcggt ctcgctcagc     4560

agagccccga ccagagctgg gcccaggcca ggaaacaggc accaattccc gaggaaggtc     4620

gcctagcccc attggggtgg ggtcagagat gtgcagggag gaagggggag agggcacgcc     4680

agtgaagcag gacttatctg ctccccctgg ctacacgctc actgagaacg tggcccggat     4740

cctcaacaag aagctgctgg aacatgcctt aaaggaggag aggaggcagg ctgcccacgg     4800

gcccccgggt ctccacagtg acagccactc gctgggggac acagccgagc cagggcccat     4860

ggagaaccaa actgtcttgc taactgcccc ctggggactc tagccctgcc cgcctcacgc     4920

tgaactacct tgttctgcac tagctccatc cctagagccc tgcttctcca ggcccgagag     4980

accagcaaac cgtcgccctc cgtcccgttg ggccccacat tcccccactg cctcacagcc     5040

tcagtcaccc ggagacccga cgtccttgga ggagcatggt ggcgaggagc cgcccgagga     5100

gcagccacac cgagatgcaa gcttgcatgg attatcacag tataattcac tgtaatttgc     5160

ataaccacac catcaccatg aacaaaactc tgcccaacag gagagatcta gttttctcaa     5220

ggtcaaagaa tgttttttaa aaacacaaag ctgctgaatg ttcaacctgt gaaactgaga     5280

tgtttctaga atgaaacagt aaatgtgcct gtaataactt aatttttttc atagctcaga     5340

aaactatttt tgtctccatc ttttttacac acagtatatt aaacgaaaag gtaaataagg     5400

tataaataga tttaaaaaat aaaagtttta aaaaatgtac attttaagag attctgaaca     5460

ccctcgctgt caatacctga ctgcctctgt taaatttgca ctgttacatt ttggttcagt     5520

ttatttccat gttgaattag agtggattaa gttaatttta ttttgtcagt gttactgttt     5580

tttacgaatt ttttaatgct tcagactgtc tgattcagtg aactttttgt agtgaaaaag     5640

ccatgaagcc agtagacaag acagatattc tgtatgctgg aggggataca ggatgatttt     5700

gaaaaggtac aaagtcctca gtgggcttag aaaattcact gtatgatcct tatattatcc     5760

tacttggctt gcacgtcttc gggtgcatgt atataccgct actgtgtcct cgccatcacc     5820

taaatgtgac tcagtctgtt ccactgtaat atgttgtgaa tttccttgta ctgtactttt     5880

attgttggtc ttcttgcatc gatgatccaa cagcaacacc atttttaaat tattgtgaaa     5940

agattaactg gcaatgtaca gagtttactc aaagttttct taagggaaaa cactacaaaa     6000

agtcacaagg ataccaaatg gaaacacatg atgatgcctc tgggtctgta tgagaccgtg     6060

atgaagtaga aataaagccc ttctgagatg gc                                   6092


<210>  1214
<211>  2449
<212>  DNA
<213>  homo sapiens

<400>  1214
gccccctgca ttgctgatgc tgctgctggc ggacatggac gtggtgaatc agctggtggc       60

tgggggtcag ttccgggtgg tcaaggagcc cctcggcttt gtgaaggtgc tgcaatgggt      120

cttcgccatc ttcgcctttg ccacatgcgg cagctacagt ggggagctcc agctgagcgt      180

ggattgtgcc aacaagaccg agagtgacct cagcatcgag gtcgagttcg agtacccctt      240

caggctgcac caagtgtact ttgatgcacc cacctgccga gggggcacca ccaaggtctt      300

cttagttggg gactactcct cgtcagccga attctttgtc accgtggccg tgtttgcctt      360

cctctactcc atgggggctc tggccaccta catcttcctg cagaacaagt accgagagaa      420

taacaaaggg cccatgctgg actttctggc cacggctgtg ttcgccttca tgtggctagt      480

tagctcatcg gcatgggcca aggggctgtc agatgtgaag atggccacag acccagagaa      540

cattatcaag gagatgcctg tctgccgcca gacagggaac acatgcaagg agctgagaga      600

ccctgtgacc tcgggactca acacctcggt ggtgttcggc ttcctgaacc tggtgctctg      660

ggtcggcaac ctgtggttcg tgtttaagga gacaggctgg gccgccccgt tcctgcgcgc      720

gcctcccggc gcccccgaga aacaaccggc acccggggac gcctacggcg atgcaggcta      780

cgggcagggc cccggcgggt acgggcccca ggattcctac gggcctcagg gcggctacca      840

gcctgactat ggtcaaccag ccggcagcgg tggcagtggc tacgggcctc agggcgacta      900

tgggcagcaa ggctacggcc cgcagggtgc acccacctcc ttctccaatc agatgtagtc      960

tggtcagtga agcccaggag gacctggggg gggcaagagc tcaggagaag gcctgccccc     1020

cttcccaccc ctatacccta ggtctccacc cctcaagcca ggagaccctg tctttgctgt     1080

ttatatatat atatattata tataaatatc tatttatctg tctgagccct gccctcactc     1140

cactcccctc atccactagg tgcccagtct tgagtgggcc ccctctctta ccccgtccct     1200

ttccctgcat cccttggccc ctctctgttt accctccctg tcccctgagg ttaaggggat     1260

ctaaaaggag gacagggagg gaacagacct cggctgtgtg gggagggtgg gcgtgacttc     1320

agactctctc ctctctctcc ctccactcct cccaactctg gccttggttc ctccagcaat     1380

gcctgcctga acaaaggccg ttagggaaat ccaactccag ggttaaagaa aggcagagat     1440

tgggggggct tggggtagag aggacagttt aggacccaag gtggtcttgg agaggaggtg     1500

tggagtggag gggtcagcag gggggttggg ttccagacag agtggatctg gagtctgaag     1560

gagaggagtg cgctagagca ttctggggtg gggcttggaa gggcgctgag ggcagggttc     1620

tagaaggggc gaggctttaa gcgaggcaga atggtgggct ccagagtagg tgggtcttgg     1680

attggtacca gagcctatgg aaagggtgtg gcttggaaca tttgggagac tgagcttgat     1740

tctaaagggg acagatcttg agcaaggcaa gaagtgggat tcaggaatgg gccaagccag     1800

ggttccagac agggtggggc ttagaatggg gcttccatgg tggtttcaga aagggcagcc     1860

cctccccatg gtgcagtgaa gaaaatgttt tacaatggct gggtttgggc agtggagagg     1920

ggacttggat aggagcttcc agatgggttt tgttaggggt gggggagaat ggctctggct     1980

acgacttggg acggaagtgg cctgagaaga gtcgagtgat atggcttgta gggtgaggcg     2040

tgggatccag agagaagcac cccaccacac acacccttcc ccactcccgt gatgaaacag     2100

ctaggttaat aggaggacag aaccaacggg tctgtgggac tggcccaccc ctcttccccc     2160

ttcccctgcg ccctccctcc ctccacacct ccacccgtcc tggggtggtt ggaggcctgg     2220

tctggagccc ctatcctgca ccctctgcta tgtctgtgat gtcagtagtg cctgtgatcg     2280

tgtgttgcca ttttgtctgg ctgtggcccc tccttctccc ctccagaccc ctaccctttc     2340

ccaaaccctt cggtattgtt caaagaaccc ccctccccaa ggaagaacaa atatgattct     2400

cctctcccaa ataaactcct taaccaccta gtcaaaaaaa aaaaaaaaa                 2449


<210>  1215
<211>  1196
<212>  DNA
<213>  homo sapiens

<400>  1215
ggaaaacggc ggccgcggcg tctcctccgg gacgctgagg ggcccgagga gaccgtgagg       60

ctctggcctg cagctcgcgc cgccatggac gctgccgagg tcgaattcct cgccgagaag      120

gagctggtta ccattatccc caacttcagt ctggacaaga tctacctcat cgggggggac      180

ctggggcctt ttaaccctgg tttacccgtg gaagtgcccc tgtggctggc gattaacctg      240

aaacaaagac agaaatgtcg cctgctccct ccagagtgga tggatgtaga aaagttggag      300

aagatgaggg atcatgaacg aaaggaagaa acttttaccc caatgcccag cccttactac      360

atggaactta cgaagctcct gttaaatcat gcttcagaca acatcccgaa ggcagacgaa      420

atccggaccc tggtcaagga tatgtgggac actcgtatag ccaaactccg agtgtctgct      480

gacagctttg tgagacagca ggaggcacat gccaagctgg ataacttgac cttgatggag      540

atcaacacca gcgggacttt cctcacacaa gcgctcaacc acatgtacaa actccgcacg      600

aacctccagc ctctggagag tactcagtct caggacttct agagaaaggc ctggtgcagg      660

cggcttgctg ggggatgtga gcgctcagga cgtgatgagg tactcgtggt tctggagctc      720

tagaaacact tctgatgcat gaaaaatgtg tgatggtgca aggaatggat tcaggatgtt      780

gttggagaaa caagtttgtg attagtcctt aaaacttagc tccctgggac attcttcaat      840

tccacatctg tttctagaaa ccagcccttt ttccccccac ttttgagaaa taaaaaagcc      900

ttaggtaaat aagtcattct ccctagcaga gccacttggg tctcctgcat ggaagccatc      960

acacttgggc aggtgttcag tgactggtag gtgtagatac agcaggagtg gccatgtggt     1020

ccacggcttt ttaccccttc ttgatcctga tttcttgggc tgaatttaga ctctctcaca     1080

gaggtggctc acagagaagg atggcagatg gtgcagccaa caatgctgac cggtgcttat     1140

cctctaagcc ctgatccaca ataaaaatgg acccaactca aaaaaaaaaa aaaaaa         1196


<210>  1216
<211>  3963
<212>  DNA
<213>  homo sapiens

<400>  1216
ggagagccga aagcggagct cgaaactgac tggaaacttc agtggcgcgg agactcgcca       60

gtttcaaccc cggaaacttt tctttgcagg aggagaagag aaggggtgca agcgccccca      120

cttttgctct ttttcctccc ctcctcctcc tctccaattc gcctcccccc acttggagcg      180

ggcagctgtg aactggccac cccgcgcctt cctaagtgct cgccgcggta gccggccgac      240

gcgccagctt ccccgggagc cgcttgctcc gcatccgggc agccgagggg agaggagccc      300

gcgcctcgag tccccgagcc gccgcggctt ctcgcctttc ccggccacca gccccctgcc      360

ccgggcccgc gtatgaatct cctggacccc ttcatgaaga tgaccgacga gcaggagaag      420

ggcctgtccg gcgcccccag ccccaccatg tccgaggact ccgcgggctc gccctgcccg      480

tcgggctccg gctcggacac cgagaacacg cggccccagg agaacacgtt ccccaagggc      540

gagcccgatc tgaagaagga gagcgaggag gacaagttcc ccgtgtgcat ccgcgaggcg      600

gtcagccagg tgctcaaagg ctacgactgg acgctggtgc ccatgccggt gcgcgtcaac      660

ggctccagca agaacaagcc gcacgtcaag cggcccatga acgccttcat ggtgtgggcg      720

caggcggcgc gcaggaagct cgcggaccag tacccgcact tgcacaacgc cgagctcagc      780

aagacgctgg gcaagctctg gagacttctg aacgagagcg agaagcggcc cttcgtggag      840

gaggcggagc ggctgcgcgt gcagcacaag aaggaccacc cggattacaa gtaccagccg      900

cggcggagga agtcggtgaa gaacgggcag gcggaggcag aggaggccac ggagcagacg      960

cacatctccc ccaacgccat cttcaaggcg ctgcaggccg actcgccaca ctcctcctcc     1020

ggcatgagcg aggtgcactc ccccggcgag cactcggggc aatcccaggg cccaccgacc     1080

ccacccacca cccccaaaac cgacgtgcag ccgggcaagg ctgacctgaa gcgagagggg     1140

cgccccttgc cagagggggg cagacagccc cctatcgact tccgcgacgt ggacatcggc     1200

gagctgagca gcgacgtcat ctccaacatc gagaccttcg atgtcaacga gtttgaccag     1260

tacctgccgc ccaacggcca cccgggggtg ccggccacgc acggccaggt cacctacacg     1320

ggcagctacg gcatcagcag caccgcggcc accccggcga gcgcgggcca cgtgtggatg     1380

tccaagcagc aggcgccgcc gccacccccg cagcagcccc cacaggcccc gccggccccg     1440

caggcgcccc cgcagccgca ggcggcgccc ccacagcagc cggcggcacc cccgcagcag     1500

ccacaggcgc acacgctgac cacgctgagc agcgagccgg gccagtccca gcgaacgcac     1560

atcaagacgg agcagctgag ccccagccac tacagcgagc agcagcagca ctcgccccaa     1620

cagatcgcct acagcccctt caacctccca cactacagcc cctcctaccc gcccatcacc     1680

cgctcacagt acgactacac cgaccaccag aactccagct cctactacag ccacgcggca     1740

ggccagggca ccggcctcta ctccaccttc acctacatga accccgctca gcgccccatg     1800

tacaccccca tcgccgacac ctctggggtc ccttccatcc cgcagaccca cagcccccag     1860

cactgggaac aacccgtcta cacacagctc actcgacctt gaggaggcct cccacgaagg     1920

gcgaagatgg ccgagatgat cctaaaaata accgaagaaa gagaggacca accagaattc     1980

cctttggaca tttgtgtttt tttgtttttt tattttgttt tgttttttct tcttcttctt     2040

cttccttaaa gacatttaag ctaaaggcaa ctcgtaccca aatttccaag acacaaacat     2100

gacctatcca agcgcattac ccacttgtgg ccaatcagtg gccaggccaa ccttggctaa     2160

atggagcagc gaaatcaacg agaaactgga ctttttaaac cctcttcaga gcaagcgtgg     2220

aggatgatgg agaatcgtgt gatcagtgtg ctaaatctct ctgcctgttt ggactttgta     2280

attatttttt tagcagtaat taaagaaaaa agtcctctgt gaggaatatt ctctatttta     2340

aatattttta gtatgtactg tgtatgattc attaccattt tgaggggatt tatacatatt     2400

tttagataaa attaaatgct cttatttttc caacagctaa actactctta gttgaacagt     2460

gtgccctagc ttttcttgca accagagtat ttttgtacag atttgctttc tcttacaaaa     2520

agaaaaaaaa aatcctgttg tattaacatt taaaaacaga attgtgttat gtgatcagtt     2580

ttgggggtta actttgctta attcctcagg ctttgcgatt taaggaggag ctgccttaaa     2640

aaaaaataaa ggccttattt tgcaattatg ggagtaaaca atagtctaga gaagcatttg     2700

gtaagcttta tcatatatat attttttaaa gaagagaaaa acaccttgag ccttaaaacg     2760

gtgctgctgg gaaacatttg cactctttta gtgcatttcc tcctgccttt gcttgttcac     2820

tgcagtctta agaaagaggt aaaaggcaag caaaggagat gaaatctgtt ctgggaatgt     2880

ttcagcagcc aataagtgcc cgagcacact gcccccggtt gcctgcctgg gccccatgtg     2940

gaaggcagat gcctgctcgc tctgtcacct gtgcctctca gaacaccagc agttaacctt     3000

caagacattc cacttgctaa aattatttat tttgtaagga gaggttttaa ttaaaacaaa     3060

aaaaaattct tttttttttt tttttccaat tttaccttct ttaaaatagg ttgttggagc     3120

tttcctcaaa gggtatggtc atctgttgtt aaattatgtt cttaactgta accagttttt     3180

ttttatttat ctctttaatc tttttttatt attaaaagca agtttctttg tattcctcac     3240

cctagatttg tataaatgcc tttttgtcca tccctttttt ctttgttgtt tttgttgaaa     3300

acaaactgga aacttgtttc tttttttgta taaatgagag attgcaaatg tagtgtatca     3360

ctgagtcatt tgcagtgttt tctgccacag acctttgggc tgccttatat tgtgtgtgtg     3420

tgtgggtgtg tgtgtgtttt gacacaaaaa caatgcaagc atgtgtcatc catatttctc     3480

tgcatcttct cttggagtga gggaggctac ctggagggga tcagcccact gacagacctt     3540

aatcttaatt actgctgtgg ctagagagtt tgaggattgc tttttaaaaa agacagcaaa     3600

cttttttttt tatttaaaaa aagatatatt aacagtttta gaagtcagta gaataaaatc     3660

ttaaagcact cataatatgg catccttcaa tttctgtata aaagcagatc tttttaaaaa     3720

gatacttctg taacttaaga aacctggcat ttaaatcata ttttgtcttt aggtaaaagc     3780

tttggtttgt gttcgtgttt tgtttgtttc acttgtttcc ctcccagccc caaacctttt     3840

gttctctccg tgaaacttac ctttcccttt ttctttctct tttttttttt tgtatattat     3900

tgtttacaat aaatatacat tgcattaaaa agaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaa                                                                   3963


<210>  1217
<211>  1742
<212>  DNA
<213>  homo sapiens

<400>  1217
agcgcggtga gtttgaaact gctcgcactt ggcttcaaag ctggctcttg gaaattgagc       60

ggagagcgac gcggttgttg tagctgccgc tgcggccgcc gcggaataat aagccgggat      120

ctaccatacc cattgactaa ctatggaaga ttataccaaa atagagaaaa ttggagaagg      180

tacctatgga gttgtgtata agggtagaca caaaactaca ggtcaagtgg tagccatgaa      240

aaaaatcaga ctagaaagtg aagaggaagg ggttcctagt actgcaattc gggaaatttc      300

tctattaaag gaacttcgtc atccaaatat agtcagtctt caggatgtgc ttatgcagga      360

ttccaggtta tatctcatct ttgagtttct ttccatggat ctgaagaaat acttggattc      420

tatccctcct ggtcagtaca tggattcttc acttgttaag gtaaaagctt aactaatttt      480

attaatattt atgcactgtg gatataaagg gactatatat agaagtccct gcattttgtg      540

ggaatatgct tggaaaaagt gttagaataa gaaaaagtat ttcatttttc tccctcatgg      600

ttagtttata caggttagag atacccatgt tattaccaga tagtgtttct agtaagtaaa      660

aattagtgcc tgagataaca tagaactggt aggtattgtt ggaagctagg gtagtctggt      720

ctttctttgg ctgtcagata catgtaaaac aaagtaatga aagcctaggg cagagtggtg      780

gttgtaggtg ttttattcca gttttgaaca tgttttggtc aatttattgt agacatttat      840

tatatttcag gtaaattata aaattgtata gttttaagta ctgaagtata taaaagtgtc      900

ttattcttgc accagttcta ccaaaccact ctgcagaggt agcgctgtta gttttatttg      960

taatcttaca cttgtatgta tgttcacttt gtatgtatat aaagattttt ttttttacac     1020

aaggtggact tatttgcata tgtatatata catattttcc cttttttgtg taaaacatta     1080

tcaagacgta gatctaccta tgtctattta catttttgat ataattaaac cacttccata     1140

ttgatgaaca tttaaattat tttccaactt ggttattgtt gctcttatta acagtactgc     1200

actgaatgtc cttatagata tttatcttcg tatgcaactt tataggataa atttttagaa     1260

tgggaatgat ggattgaaga tgtttattta cattttgata gatattgccg gttgccccct     1320

aaaaaacttg tagcaattta ctcttaaata ctcatggtgt gtaatactta ttgttttagt     1380

acatcattgc caaaacttgg ttttatcaat ctgttaacta tgtgaaaaag gcatattaag     1440

attgttttaa ttttatattt catgacaatt taacacttca tatttagcta ttataaaccg     1500

cctatatttt cgttaggata cgttctttaa caatcttgca tgacttttgg actttctgct     1560

tttatgtctt gcttaagtct tcctcactca aagatcgaat gtattagaat aatacatgtc     1620

agtatttttc tggtagtttt agtaagtcct gtcttccaca catacttttt ttgtcttaaa     1680

ttctgtatta agatttattt tgacttaaaa actgggatac agattctgct ttatcttttt     1740

cc                                                                    1742


<210>  1218
<211>  2486
<212>  DNA
<213>  homo sapiens

<400>  1218
gcgagagttg cttttgcgcg cgaactgtaa gtgccagggt ctcagggtca ggtcgcggct       60

ggtcactgtg caggcgcttg ggtgacgcga cgatctcagc ggatctggtc accttcgtct      120

ccccgccatg gagacctcag cactcaagca gcaggagcag cccgcggcga ccaagatcag      180

gaacctgccc tgagacaggg tctcgctctg tcgcccatgc tggagcgcag tggtgtgatc      240

acagctcagt gtaacctcaa acattggggt tcaagccatt ctcctgcctc agcctccgaa      300

gaactgggac ttttagaggc gagctaccaa gcccatcctg taaccatttt aaaatgtaca      360

attcagtggc attaagtaca ttcagaatgc agtgtactgt tgtggagtct tcccgctatc      420

tagttccaaa atttcatcac cccaaatgga aatcctttac ccattgacag ttactcccca      480

ttctcccctt cctctagccc ctggcaacca ctaatctgct ttctatctat ggatttgcct      540

attctggaca tttcatggtt gaaaaatacc ggccacagac cctgaatgat ctcatttctc      600

atcaggacat tctgagtacc attcagaagt ttatcaatga agaccgactg ccacacttgc      660

ttctctacgg tcccccaggg acaggcaaga catctaccat cctagcctgt gcgaaacagc      720

tatataaaga caaagaattt ggctccatgg tcttggagct gaatgcttca gatgaccgag      780

gaatagacat cattcgagga ccgatcctga gctttgctag cacaaggaca atatttaaga      840

aaggctttaa gctagtgatc ttggatgaag cagacgccat gactcaggac gcccagaatg      900

ccttgagaag agtaattgag aaattcacag aaaataccag attctgcctc atctgtaact      960

atctgtcaaa gatcatccct gccttgcagt cccgctgcac gaggtttcgg ttcggtcccc     1020

tgactcctga actcatggtt ccccgcctgg aacatgtcgt ggaagaagag aaagttgata     1080

taagtgaaga tggaatgaaa gcactagtca ctctttccag tggagacatg cgtagggctc     1140

tgaacatttt gcagagcacc aatatggcct ttgggaaggt gacagaggag actgtctaca     1200

cctgcaccgg gcacccgctc aagtcagaca ttgccaacat cctggactgg atgttgaatc     1260

aagatttcac cacagcctac agaaatatta cagagttgaa aactctgaag gggttggcac     1320

tgcatgatat cctgacagag atacacttgt ttgtgcatag agttgacttt ccatcttcag     1380

ttcgaataca tttattgacc aaaatggcag acattgagta caggctttct gttggcacca     1440

acgagaagat ccagctgagc tccctcattg ctgcatttca agtcaccaga gacctgattg     1500

ttgcagaggc ctagatgctc tgagggccat tcacaattct cagggctcag cagtgatggg     1560

agaacagagg acagttccag gataaactgc tgcctggggc tgtgggatga atcagtcacc     1620

ccgaatcttg gaaaaacccc cttccaggag aggatgggca ggcatttaaa aagtaccatt     1680

tttgtggttg tttggagcag ggatgtacaa aataatttta atgtattaac tcatactgcc     1740

tgtcttttat aggggaaaaa aataaccttt tttattttaa agttataagg tttttacctt     1800

ttagttgctt ggatgacagg gaattagcct accccatttt ggtctggaac agaagacttt     1860

caaatttaat atggtccaag tgtcttccta ctcaaggtaa acattatctc caaaattaca     1920

tttatgattc taatatttgg cattgtgtct gtatctaatt taaacagatg ttaatggacg     1980

tctggccgaa actattatac ttttataaga tgagctgaat cctcttactt taaaaactgg     2040

tctttttatt taccctctgt ggtagaagag tcaccagcag gttccaaatt gatgtgtatg     2100

ataggaaaaa aaccttaatt ttaaatataa tatagagcct taaactatgc cactgggtgg     2160

cagaggctgt ataaaacgca cttgttttca tgcaggagcg gggcaagtaa ggttgagcct     2220

gactgtaaac ctagaactgc ggaaggactg ggacttttgt acaaatttca catttatttt     2280

acagcaatca tgctgcattt gtgttagtgt tctttataat aaaaaacaaa gcagcctcct     2340

ggctggctgt gttacaagtg actcttcctt agacagctag aaagatgctg actttgtcaa     2400

acttgcattt atatgaaaac cttctgtctc taatatcaca gaataaactt tctttagatg     2460

ctgttcttta taaaaaaaaa aaaaaa                                          2486


<210>  1219
<211>  16142
<212>  DNA
<213>  homo sapiens

<400>  1219
gcccccgccg cccccgggcc ctgatggact gaatgaaggc tgcctacacc gcctatcgat       60

gcctcaccaa agacctagaa ggctgcgcca tgaacccgga gctgacaatg gaaagtctgg      120

gcactttgca cgggccggcc ggcggcggca gtggcggggg cggcggcggg ggcggcgggg      180

gcggcggcgg gggcccgggc catgagcagg agctgctggc cagccccagc ccccaccacg      240

cgggccgcgg cgccgctggc tcgctgcggg gccctccgcc gcctccaacc gcgcaccagg      300

agctgggcac ggcggcagcg gcggcagcgg cggcgtcgcg ctcggccatg gtcaccagca      360

tggcctcgat cctggacggc ggcgactacc ggcccgagct ctccatcccg ctgcaccacg      420

ccatgagcat gtcctgcgac tcgtctccgc ctggcatggg catgagcaac acctacacca      480

cgctgacacc gctccagccg ctgccaccca tctccaccgt gtctgacaag ttccaccacc      540

ctcacccgca ccaccatccg caccaccacc accaccacca ccaccagcgc ctgtccggca      600

acgtcagcgg cagcttcacc ctcatgcgcg acgagcgcgg gctcccggcc atgaacaacc      660

tctacagtcc ctacaaggag atgcccggca tgagccagag cctgtccccg ctggccgcca      720

cgccgctggg caacgggcta ggcggcctcc acaacgcgca gcagagtctg cccaactacg      780

gtccgccggg ccacgacaaa atgctcagcc ccaacttcga cgcgcaccac actgccatgc      840

tgacccgcgg tgagcaacac ctgtcccgcg gcctgggcac cccacctgcg gccatgatgt      900

cgcacctgaa cggcctgcac cacccgggcc acactcagtc tcacgggccg gtgctggcac      960

ccagtcgcga gcggccaccc tcgtcctcat cgggctcgca ggtggccacg tcgggccagc     1020

tggaagaaat caacaccaaa gaggtggccc agcgcatcac agcggagctg aagcgctaca     1080

gtatccccca ggcgatcttt gcgcagaggg tgctgtgccg gtctcagggg actctctccg     1140

acctgctccg gaatccaaaa ccgtggagta aactcaaatc tggcagggag accttccgca     1200

ggatgtggaa gtggcttcag gagcccgagt tccagcgcat gtccgcctta cgcctggcag     1260

cgtgcaaacg caaagagcaa gaaccaaaca aagacaggaa caattcccag aagaagtccc     1320

gcctggtgtt cactgacctc caacgccgaa cactcttcgc catcttcaag gagaacaaac     1380

gcccgtcaaa ggagatgcag atcaccattt cccagcagct gggcctggag ctcacaaccg     1440

tcagcaactt cttcatgaac gcccggcgcc gcagcctgga gaagtggcaa gacgatctga     1500

gcacaggggg ctcctcgtcc acctccagca cgtgtaccaa agcatgatgg aaggactctc     1560

acttgggcac aagtcacctc caaatgagga caacagatac caaaagaaaa caaaggaaaa     1620

agacaccgga ttcctagctg gggcccttca ctggtgattt gaaagcacaa ttctcttgca     1680

aagaaactta tattctagct gtaatcatag gccaggtgtt cttcttttgt ttttaatggc     1740

tatggagtcc aagtgcaagc tgaaaaatta atctcttaga accagacact gttctctgag     1800

catgctaagc atcccagaaa cccaaatggg gccttcctgg agcgagttaa ttccagtatg     1860

gtgtcaacca agctcgggat tgcttaaaat atcatccatc ccacttcagg tcctgtcagc     1920

ttcttgcagt cagagttcct atgagtaaca ataggagttt ggcctatgta aggactctga     1980

gtttaggctt ccaagataca acaataagag aagaatctag caacgagaat gacctcattt     2040

gctttccaca tgcttagcct cattatacca tgttatgtcc aagttcacag ccacaacatc     2100

agaatggtaa ttactgagca caagttttaa atatggacgt taaaaaaaaa aatccaagga     2160

cctgtttttc caacccagac atcttttcat tgaatgattt agaaagcttt aagttgatcc     2220

agcttacaat tttttttttc tttacctcct ggaaatctca tatggtcttg gatccgtcaa     2280

aaaaaccagt cagttcactt gcgctcaaag tatcaagcac aacaaagata aacagaagtg     2340

aggaaggttc tgggttcact acatctggat tttcaagaca cctattgtga agtcattagg     2400

gaattgatga gaatatggct tcaagcacat tttgcagttt gctacaaatt ctgttgtaca     2460

taatgcagac gcacactcag gaggccaatt taactgttaa cagtgcatgg agcgaatgca     2520

gcattttaaa agatctaggt ttttttaggt cattaatgtg tccttggttg atcagtcatc     2580

tggtccctcc tactgtgtgt tatgaccacc acgtaatcca ttctcgctct ttctgatttg     2640

gggtttttcc tcatccatcc cattagtagg gatgttttct gtgttttcta gcaagaaaaa     2700

aaaatcaatc aatcaaacct gcatacatgt tactcatgac tgtcatctag tcctaaatct     2760

cttctgttgt tgaatcatcc ttgcaaaaca gctgaataca tctggagaaa acacagcaca     2820

ccaaagaagc agaatactgc aaaccaaaga catttatgac ttgtcatttt ctagcctaaa     2880

aatactgtga ttacttttag aaatcagaaa acctctgcaa ctccgaatgg cattcagctc     2940

ttgcatttgg cgcatcatcg ggctgagcgg accagctaca ccaaggacat tagccaagcc     3000

acccagaggg gtggctttgc cacaccagtt gtcaccttcc catagcaagt ggaagagcgc     3060

ccacagaact ctgggagatt gcaaaggtca caatgtgcat atttaccagt gaatggcccc     3120

gggtggggcc acgtgggggt gttcaaagca agccaaacgc tgcaatcatt ctttacagac     3180

acttgagact gactttttta tgaattactt agtcgaaacc aaagaaactt tttctgcacc     3240

tacttctgca acaaacaaaa ctgtcccatt aaaatgaata aataaatccg taaatcaatg     3300

gaaatcacca ccaataagaa ggaagcacgc cagaaaataa acgaaaacaa aaacagggag     3360

acacactgtg ttcaaacaga cctcttggga cattttttgg aagcagattt taaagaaagg     3420

gttgagacaa agatagaaat aaggaagagc ctcagtggct gctgcttcat ttgacaactc     3480

acacggtaat cttaaagctg aagattgtct ttaatttgtg cctatgcagt ttttcaaaag     3540

aacacggaac agagcaacag aaacctcaac agctacaata ccaaagatga ggatttctca     3600

caccttttgt ttcagttcat tatctcctct tgcctggcta aaatactaat agcgccattg     3660

aactgtataa aggtaatcaa ttatgtttct ctgagcaaca aaaggaaagg gccatttatt     3720

tgattttatt gtttcatttc aattttgtct tatggttttt tgccccaaca tggaatctct     3780

caaaagtttc catggactcc aagtttaaga tgttgggata ttgaacagtt ctctctgctc     3840

agcagagggt agggaataac attatcactt gaatgttctt tgcttaaccc ttagacttgg     3900

ttccttctat gttcagagtc tcatcatcag gggaaggaaa gggagtgagg gtcagggata     3960

ggggtcttgg tgatgcatcc tctcccgagc cacagaacca aagagtttat agaggaattt     4020

acagcctcgt tttcatgtga ttgctacatc ctaacagggc ttcatttggg ggtgggggga     4080

aacatgtaaa aataattgcc agtttctact tttctattag ctttttaaaa atcagctgta     4140

aagttgcatt tctaaagaaa gatatatata atatataaaa tacatatata gatcaacttg     4200

acattggtga taaccaaaat tattgctgtc caaattcatg tcttgttttg gtccagtgct     4260

tcatttgcta agtattcggt tcagaatttt tctcatttct catgccattc cagagttaat     4320

ttgccactgt ggatgatttg aagtattcag atctctatgg aagtttctgg gacaggttta     4380

aagtcaagat caagcatttt agcatttaac ctgttgataa atggatccat ggtgtacatg     4440

agttttattt gtattcggag tcatctctat tctatccctc agcctcgatt aaggtggtga     4500

gtgaagtgca tccaacagac tcggcccaga actgggtcct gacagtgggg tgctcatctt     4560

ctgtaactgt tgggaaggct cggtggtcca ttttcaccag ttaaagaata tgaggccagc     4620

ccagaaatct gttctccagg agctgccctg tcccatctgg gtgtgccaga ccccctcagt     4680

gagcaggtcc accaaaggga cttctcacag gggaagccca actcctgttg caatgggttg     4740

atagatttcc tcagggtggt aattaccaat tcgtattttg acaagcctat gtgcaaccac     4800

agctggcact ggggtgggca gtggtgttgg gtgggatggg ggagagtgtc tcaatcctga     4860

agagaaaata taaagcaggt tttggggaga cttctggagt cctgccccta gagagcccca     4920

ttgttgttct ttgtgccccc tcctcattcc ccctatgtgg gtctccctat gcaggagctg     4980

tgagagaatg tgactctcca caatttttat aattcatcct tcctaggaga ttgttcattg     5040

gctcttccct tgtgtccctt tgtcccttgc tcatactcca tgtttccttt gtcaaaggac     5100

taagaaaaga gcatatttca gcagaggagt gttcccatgt gggttgattt caacttgggt     5160

atttctaaaa gagtccttgt gacatgtgtc cagtggaaat ggttgctctt ttccagactg     5220

gattgaggaa tggagcctgt ttgatttggt tagtgattct ttgacatact aatctcagcg     5280

tttgggtctc cagcatcctc tgaagatgtc tagactagta gaggctgcct ttgtgacctg     5340

acattacaac attggtcaaa ccagtcctct gataatcaga agaacatgtc ataattgttt     5400

aaaaaaaaaa aaaaggcaag aatttctctc caaggagctt taataaatgt ctcattccag     5460

ataatgtcat accagagaaa agtgcttgct tttagaaaat tatttacata catatataaa     5520

tatatatgtg tatctataca gttatgtatc aaaattttaa gccctgcaga atttcaattt     5580

gttagaaatc taacagaaaa aaatttctat attgaaaggt aatagaattt aacccagtga     5640

gtttactcaa ggatttttaa atttaagtta ataatttcag agaaaataac catttgggtg     5700

tggttatagt ttagtatcca ttacctcaat ccaaggaaaa ttccaggcat tcctcaacca     5760

tcaggaaaag gtacagtgtg aaggaacagt tctcagccaa atttcacatt cttgaggcaa     5820

cagaaatcaa aacactcaga gccattgagt ggaaaaacaa tttactttat tcctttacac     5880

aaataggctt gcattgtttt tgttttaatg tgattttggt actagggata taattatttc     5940

attccaggaa ataataaaaa aaaacagaca gagccaatac atttcttttt ttaaaggaaa     6000

cagcaacaac aataaaaact cagcaccaat atttaaaagc ttttccaaaa tgtaaaagaa     6060

gtgtttagct tgcaccatgc ataaaggtgc aggctagttg aaccaggaag catggcactt     6120

cctctggaga aatccagaaa gagttgcttc taagctccct tttccccctg caggctcttg     6180

gcaattgtag gctttagcaa atccagaata attttcaatt caagctaaaa taaaatcaac     6240

atttggaatg taaatctgat acacacacac ttttctaagt caaacaacat atttcaaaac     6300

caaaaataaa taccttttag ataatcagtt attttctttg tctatactgg gcacccacct     6360

actagtgcca gtaaattcaa gttgaacaga tttttaaaat cactattatc tgggtatggg     6420

ggaaacttcc ccacttttga aaatgttggt agaattatag gaatgtctgt ttgattatca     6480

ttaccaaagt gtcatgacag tatgcctttg tagtgaactc ggattttcag gagtttgaat     6540

agttggatat tttaaaatct aagaagaaaa ggcctgtttc caatgttgtt gaagaataat     6600

gaactctatt aaaaagtgga gaaaaagata atacatgtgg tcaaggttga ccacaaggcc     6660

caggcacaac taccttggcg ataatcttct agattcgtaa caggttagag ctgacttttt     6720

gtttttgttg ttgctgatgc tgtgtgattc agacttctca gcctaaccag gaagagtaag     6780

tggaaatggt agatgaagaa ggggtagagc tggtgtatct ataactttct gatatttgtc     6840

tgccaaactt gatatattag taattttttt atctttagct aagatcaagt cacccctgaa     6900

acaacaggag attctagttt taaaataagg ccacaaaaat ccttacggaa tgaagaatgg     6960

caccccagtt ggttgtataa gtctcataag ataatgatgt tgattttaaa tatggatgtc     7020

tcaatgcctg ttttctatca atgatttgtt tgtttccaag gtcggggagg gaaagagggg     7080

agggtttatc tgttttagaa agtctcagaa tacttataaa atacagaagt agttattaaa     7140

atatatagga cctcacatag gtagatacag aacttaccat tgaggctgat gggctgttgt     7200

gtgaatcaca caggacctta aatgaggctc attattctca cacaccaaaa tgactctgac     7260

agcctgaagc agttattgct agagcccaag ctttccttgg aggttttgga gttaggttga     7320

ttggaagtaa ccagctaata ccttttctag tggagaaaaa gacattgcta ccagcttgtt     7380

catcccatag aagtcttcca ctctgctcca tttttagcag caagcatttc atgtagcata     7440

aaccttggca gataagtgtg cctaaggttt atacagtctg tccgcttgga tgtatacaaa     7500

tttagataca tattttaaca tgtgttctca tagatgactt tataacaaca cacattacct     7560

ataggtgtct agactgtgta catacaagtg tgtacagaca agcttcatac gtatatactg     7620

taatccgtta caacaaataa attttaaatc atcgtttaac atgtatgtgg tacttctaca     7680

gtgtacattg ttttcattat ttattgtaac attgaaaacc acagtgcagg gaaaacaaaa     7740

gtatcccagc atcttcatcc tgtacacttg gaattaattt catttgggca tatccaagat     7800

aaactcaact ttcaagaaat cttgtatatt atttaatcat ctgtgttagg atgacaccta     7860

tgattgatga cttcggttga atagctttat tctggatttt tcataactaa agctaaatcc     7920

aaagacctga aaaaggacaa aaagaaaaaa aaaaaaagaa aaaacaaaga aaaagaagaa     7980

aaaataataa agtcaagcgc aaactgatgg ggagacagtg ggctctggtt tccaggattg     8040

agacaatggt actgcggtct tggggagact gcgttagcta gtggggagtg gtgatttttt     8100

tcatgcttgt cacatctaaa tggtctttaa catgagaaag ttttagaggt tataatttcc     8160

tgctttgttt ttatttagac tatcaaatga agttatacat gttgtcagtc aaaaaatgaa     8220

gacaccctct gccccacccc acagaatgct ttttatcttg tctctttggg ttatgaccca     8280

acaagctaag taccattaat gtaattaact tatttaaatt agttcctagt acataaatgt     8340

ataggatttg ggtaattatt taatcatcct tccttagttt gattctactc cttgtactta     8400

tttatcaaaa cctagaccaa tggtgcatca gagatgcaaa attctacttg gaatactctt     8460

gaagtttagt ttgctttata aagcagtgaa attctgttac agacagggaa gaaatacagg     8520

ttacaaaaag agaatttggg atattcttcc ctcttaaatt aacttttaaa atagtctaag     8580

taacaatttt taaattattt aacttaagtt cgcagcccca cctggtacca ggcgaacttc     8640

acctcttaat tattgtggcc ctcggagcct tcatattgta acttatttat ttaacttatt     8700

cagcatctgt gaaaggtgca ctgtatagtt tatattttta atttaaaaca acagagagca     8760

ctgcagtttg tttgctgtca gaacaacaga gcaaattttg tggacaagca atgactattc     8820

agcctgaacc tgtgcattca gaaaacataa gctgagaccc tgcttcacca gcctggattt     8880

cggggcttct atacagaaac tggaaaaata aattttaaaa aaatcgtaaa caaaaagaga     8940

gaaaccctta cactagctgc ttccaagaat gaactctgtg tgtatgtaaa gcaacaaaac     9000

aaaaaaggaa aaaaacaaaa agcagaaaaa agaaaaaaaa aatgaaaaac tttctatttc     9060

tagtgagaac caaagaaggc tacctcactg actttttcca tttgtaattt taatcgtgtt     9120

gatgacacca aagataccaa agatttcttt ctctgtgcgg tctgcatttt gcttgtgctc     9180

ttttataatt tgaacgattt tctctgacat atggtatgta cagccacagc tcagataccc     9240

caaagaaata attatctatg cgacggcggc tgctaatttg gaaagggata ttttctgtgt     9300

ttctcttata tgtttgctgt ctgctcgaca tgttcaagat gcgagttcag atgctgctgt     9360

aattggattc cttaaattct gattacaaat tgaggaagga aactggttgg aaatggcctt     9420

cagtcctagc catggcctct atccccgctg ggacctgtca cagtaaagac tgccaattac     9480

tgaaccacag aagctctgac cattgagtag ttgagctgga agagacctta ggaatcattt     9540

agtccaagcc ccggtggccc agaggaatga aatagttatc caaatcaaat aactcttgag     9600

agtgaaagcc cacacatgcc tcctggttcc tgccccagtg ctccgcttat tgtacagtgc     9660

tacctctgca tgagagcggt cccacattga caaataggat ggtggcaatc ctttagcaat     9720

gagcagggac tggggtttat ctcttaacat tttcagctgt aaaattagtc acaagcattt     9780

tcagtgtccc attagtacat agtcacatat ggtcggttgc ttcgtgaagg tggcctgtct     9840

tgaaatacta gggctcatac gggatttttg ccctaggaaa aacatgttga tcccaatgat     9900

gtgatcactt ttgaaccttt ccattacaaa gcattgtata gataactttt taattcagta     9960

ggaggagaaa gttcattctt ggcctgttgg ctttgattat tatgggtact ttaaagtcag    10020

tatttatcaa gaaagggaac ttgaccacca ttggcacatg tgacatttaa gctcttcagc    10080

cttttccttt ttagttgtag gtgtttacat ttcatttcta agccaactct gtatttatga    10140

gagaagttta agccttacat catttgatac taaagggtta tttgtggtaa atgaaaaatg    10200

accccaaaat tacagaggaa tatgccagtt taagaaatgg ctacttaaag ttgcttctct    10260

ctttccttct tactcatgaa attaattggt cttcttcaag tttctttaga ttccattaaa    10320

tgattaaatc actattaaga gccattcatc aacgtgattt gtgtgttagc caatgaatct    10380

gtctcagctt ttgaccaaat gggttttaga caaatgcaaa gatctgcctc tagtccatat    10440

ggctcttttt gagtgctagt attttgcatt tcacataatg tagttatttt gagcttttaa    10500

agagagcatt tagacaaaga agcaaagaga ggaagggacc aatcaactca tcagttccat    10560

gcatcaacaa agcatagcta gtagaggaat ataaatgaca gattgacaaa ctgtaggaaa    10620

cactgttact ctctttctga agttttcaag caccatccta tgtgaaagtt ccctcctgtc    10680

caaacaagct caaggcccat cttctcccta tacaaggcaa acctgtaagg ccttccttcc    10740

aaagagtaca ttgctttggt tttcttccta aattcctatt ggaattagaa ctctcagaat    10800

ccctgggaga cagagcaaag atgacttaat tcattgagca gcagagctcc ctataagtga    10860

acatcacctt ccccatcttt cctactgcca cacccatacg agagaggatc tagaaagagc    10920

gatggcagcc tgaacacaga aaacatcccc acttggcaga cctctcctca gcaatccccc    10980

cagcctcatg cttcacttgc aaagtgtgac ataaccacgg gacgagtgcc ttgcttgaac    11040

caaagcaacg atttagccag tctggacctc tctgtgcttt ttttaattct tcctgtgaat    11100

acctcagctt caactgggcc tccatacagt cagttggtgg gcttattgta ctgtggtgct    11160

ttgcaatgca accctgcaaa gaacaagatt tgtactaata ccaaaggttc tttctctatg    11220

tctcctcctc tgcctccctc gttcttccct tttttctagt tcttcacggt tccaaagctt    11280

tactatgaac ctgggcatgt tggcaatgca gaccgcgcaa ttccttaccg aattttctca    11340

gatatacctc atagacaata gtgtttagag taatgttatt atagcgtatg taataaatta    11400

ttcactgttt cttttggtaa ctgtgattta aaaaaagaaa aaagaaaaaa aagctttata    11460

cgttttaggt tgtgcttttg taatagatga aaaaaggtgc gcttaaaaag aaaatgtatg    11520

tttttttccc cctttggatt ttatttatgc tggattgggg aaagttgcag aatgagccca    11580

aagtttacag tttcatattt tgctgaagaa acaatctgtg ttcatttgct ctgttgaaaa    11640

gaataattat tttctacatt tgtgccactt ggtctgaaca attaattgtt ccgtgttaac    11700

agtgtagtat tatgattagc aactgccaat cagtgctata attttatgca tgaggctaaa    11760

aatttagcag tgtgatgcat tgtggtctta atagcaacat ttttcatttt gaactagatc    11820

ttcccctttg gttcaatgga ctttatttat gcatgggcgc ctattgtttg ttagcagttg    11880

tggaacagtt gtgtatacat taaactgtga aaatgtacac agttcagcct cagacggtgg    11940

taatattggt tttattggga gatgtgtcac ctcgaaaata ccctttacat ctgttgggat    12000

ctgaaaatga gtcacattga attgggttcc agctttataa tgagaaacgt tattcctaat    12060

ttttgagtta gccaatttgc attccacaaa ttgggatcct cataacccaa atatatcacc    12120

gtatgtgaga gggatttgaa agcgagtatt gaaaaactca cctttgcata tttaatttcc    12180

accaaaagga gttattttgg ctttatgctc atgaacttag acctaactgg ccatgtatat    12240

gtagatgcaa attcatctag ctgtggccct ctttgatctc tgcttgggaa tggctatttt    12300

tgactatgcg tggtttcttc tcgtattttg tgatcaggtc agctcccagt agaaactcaa    12360

atggcatcaa tattactaac tcttctctgc ccacttctct tttgtccact ctcctagaca    12420

ttcccaccaa ctgttccagt gatttgggca aaaatacgca gccatttccc aaaacttcac    12480

atgtgcagct atcatggctg tccctcccta gacttggagg tgactctcac ttaattttta    12540

cctgcccaac aatgttccat ctaccatcta aaaggtaata taagaagaag ttttgaaacc    12600

cactttagga aaaccatctt ctttaaatcc ttcaattatc tgaggcctct atatgtcaaa    12660

actatttttc agttgcaggg gattgggcaa acttgttctt tcttatactt gggttcaaag    12720

acccattctc cagtttcata tttcccaaac caaaatgctt gacataaagc caaatcaact    12780

gccaagcaca ctttattttg cataggagta tgcagcctag ggaaccttgg ttgaaaagca    12840

gcagtctgct atgcaaaata ttggaaatca ctgacagtgt agcattcata ttatctgtca    12900

atgagggtat attgggaacg tgctctcgtg aataataaaa agcaacatat ttttatttgg    12960

ccttataaat taggttgtgg taatgtaaac tttgatatat agtcttttta tttttctctt    13020

attaatctgc caaagatggg aacagataca agaatttttc aaattggctt ttgtaagaca    13080

attgatgatt gtaatagtgt ttaatcttcc agaaagcttt atatgttgtt ccacaataaa    13140

attgatattt gtttcagcaa agttttcctg acactcacaa acccacaaac tgttcctctt    13200

aatgcagata ttgtagaatc tacaaagttc aaatccattt ttgatccaaa gaaagtagag    13260

gagtatttga gacatgagtg tacccagccc tttttttaat cacaggcaat gcatgggtct    13320

ggctggttac actttgccaa gaagacttgt cttatgaaac ccaaggtata ttttgttatg    13380

ccattttatg tccttttctt ttaacattgt ggaaagtggt atgttgaatc aagtgtaagc    13440

tgagttttcc agacaactga agtagctaca tcatgaatgt tattttgtta ttaaagggtt    13500

tttactcagt gctttgtgcc aatggatgtc cttttccttg gagacacata actacaaaat    13560

tacctcagct tggcctggtt ttctctcctg ccctcttggg gaaacatggg cctggcctgg    13620

gaaaaggcag gtcatgggct ggaaggtagg ttttggtact aggaagaaat ctctgtatct    13680

gtcagcttta aagagaactg ggccaaaaat ctctaacctc actctctctg gactccaaca    13740

cttccctgca atcctttggt cttgagcatg tgccagcatg aaggcagact ccagttcata    13800

catgaaaggc aagaaaaaga aaatagtaac cttgaatctt ctgtgggcca ccaggcactc    13860

acctttcccc accttgcaca ctatccagtc aaggctattg cagcccatct ggtggcttta    13920

catgggacat taccaaaggc ttcttcctcc atcctggggt tgcaaaggat ccaggtcccc    13980

tccatccagt ggggctcttc cacatcagaa gtccccctcc caccatcctc tgcatcctgt    14040

ttagctatcc catctatacc ttttggagat gattatttag aaaacaaaga aaggtatgga    14100

atggggtttc ctattgtttg ctaggttata ttttagcaat tctcaattct ttgatctgga    14160

aaaatacaag agggaaaagg agaccccact atctccctgt gctttgctcc catctcaggg    14220

ggcaggggca gtgcacattg cctatgctgt tgatctgtct tgggcgacag gctgaatcac    14280

agctattgcc ccagccaaaa acatggccca tcaatgccta ctttatctct gcttgaaaat    14340

cctattcaaa aagttgtaga gtttgaggtt tttatccccc catatccttt gctttggtcc    14400

agtttggcct ttagcataag agtcagcttt atctctagga aagttttttc agattatgac    14460

aaggaacctg ccacctggga agaaaagagt ccgaagacta gcaatcggat aggtagtcat    14520

accattaaca gatacttcct tgaaggtaga atattatttc ctttctttac agttttgtgt    14580

tacacaagtc caagtggtgc cagcaaactt cttaccgtga aatgttgtaa aacacctggc    14640

atactgaaat ttctgaaaca aaaacacaag ctccacattg ataacttgat aaataaccac    14700

taaagtttag atgcagggac tgagatgata caggcaaaat cttggtgttg gtttctcttt    14760

taattcgtat cttcgatcac ctaacctttc tcaatccaag agcagttcag tcttttctcc    14820

ccaagtctag gatgccaaag agcatcatag gaaaagataa ttagggattg accagcattt    14880

caattagttc tcttcttcat ctttgcattt ctcaaaagtg ttctcctgga ccagagggaa    14940

agagctggtc catttttttt cattctttct attcaaattt ttccacccag acaatacttt    15000

attaacacag atactgtaga tccttccttg gtcagtgaat tattacaaga ggagctatcc    15060

ttccaccaaa gtgagtgaaa acaagttcca gtatcttttc ttccatccag ttttgttctc    15120

agaatccaag tcagtcctgg gtcttttctc actttagacc ctggcctcag atgtgtttat    15180

tcttgctatt taaaaatacc tttaaatttc acatgctggc ctgcagaact tgcatccttt    15240

gttctatact gttgactgct tgatggtatt gaaaggtgac tataatgagg gaagaaagga    15300

ggaggtaaag agagaagaat ttgtcccaga tctgtttaaa gtttcaaaat ttaaaaaggg    15360

acccattaaa ttatgggaaa atggctatag agtgtgagcc tccgttgacc atatgctcaa    15420

agaccgtact ctgccacctg ccttccaggt agctattcta gaaactcagt cctttgtgga    15480

aacccaacta ccttttaaaa gtctctttcc agattccaaa aggacaagag atcagagagt    15540

cacatatacg cctcttgttt tattttcttg ctttcacggg tattattgcc aagaaaatcg    15600

tagggaaaaa ctttaaactt ttcttttcag ttgatccctt tgacatcacc tctcatgttt    15660

aaaatcagga aaacacaccc ctaaaatttg cactctcttc cgttttgaaa aagaaaaccc    15720

acacacaaat gcacactatt accgtctttc accctgcgct atatttccaa agtgtattat    15780

aatccagata ttgccccatc tcaaacatgt taagtcagac tgtgctgaaa gactttccag    15840

ggacggtcaa cagggtatat gttcagtggc tgccctgaaa tcctggtggg gatgaggatc    15900

acgcttcatc atcaagggga tgcccatccc ctgataagct cccagtcctt ttggaagatt    15960

tctttgaatg ttaattgcat tttcagtttt gctcatttcc caccccaatg ttttgtctgc    16020

aacatcgctt acactggatt ctttctattt ttattcctat cattaaatgg tagtgctgta    16080

aattctgcaa ttaatgttaa ataaactgct ttaattcatt gaaaaaaaaa aaaaaaaaaa    16140

aa                                                                   16142


<210>  1220
<211>  2262
<212>  DNA
<213>  homo sapiens

<400>  1220
gcgctcccgg ccgctctcgc ctcctctatt ggcccaggaa gcccacccag ccccgccacg       60

cagagcccag aaggaaagaa agcctcatgc ctgagccgag gggagcacca tggatctgac      120

aaaaatgggc atgatccagc tgcagaaccc tagccacccc acggggctac tgtgcaaggc      180

caaccagatg cggctggccg ggactttgtg cgatgtggtc atcatggtgg acagccagga      240

gttccacgcc caccggacgg tgctggcctg caccagcaag atgtttgaga tcctcttcca      300

ccgcaatagt caacactata ctttggactt cctctcgcca aagaccttcc agcagattct      360

ggagtatgca tatacagcca cgctgcaagc caaggcggag gacctggatg acctgctgta      420

tgcggccgag atcctggaga tcgagtacct ggaggaacag tgcctgaaga tgctggagac      480

catccaggcc tcagacgaca atgacacgga ggccaccatg gccgatggcg gggccgagga      540

agaagaggac cgcaaggctc ggtacctcaa gaacatcttc atctcgaagc attccagcga      600

ggagagtggg tatgccagtg tggctggaca gagcctccct gggcccatgg tggaccagag      660

cccttcagtc tccacttcat ttggtctttc agccatgagt cccaccaagg ctgcagtgga      720

cagtttgatg accataggac agtctctcct gcagggaact cttcagccac ctgcagggcc      780

cgaggagcca actctggctg ggggtgggcg gcaccctggg gtggctgagg tgaagacgga      840

gatgatgcag gtggatgagg tgcccagcca ggacagccct ggggcagccg agtccagcat      900

ctcaggaggg atgggggaca aggttgagga aagaggcaaa gaggggcctg ggaccccgac      960

tcgaagcagc gtcatcacca gtgctaggga gctacactat gggcgagagg agagtgccga     1020

gcaggtgcca cccccagctg aggctggcca ggcccccact ggccgacctg agcacccagc     1080

acccccgcct gagaagcatc tgggcatcta ctccgtgttg cccaaccaca aggctgacgc     1140

tgtattgagc atgccgtctt ccgtgacctc tggcctccac gtgcagcctg ccctggctgt     1200

ctccatggac ttcagcacct atggggggct gctgccccag ggcttcatcc agagggagct     1260

gttcagcaag ctgggggagc tggctgtggg catgaagtca gagagccgga ccatcggaga     1320

gcagtgcagc gtgtgtgggg tcgagcttcc tgataacgag gctgtggagc agcacaggaa     1380

gctgcacagt gggatgaaga cgtacgggtg cgagctctgc gggaagcggt tcctggatag     1440

tttgcggctg agaatgcact tactggctca ttcagcgggt gccaaagcct ttgtctgtga     1500

tcagtgcggt gcacagtttt cgaaggagga tgccctggag acacacaggc agacccatac     1560

tggcactgac atggccgtct tctgtctgct gtgtgggaag cgcttccagg cgcagagcgc     1620

actgcagcag cacatggagg tccacgcggg cgtgcgcagc tacatctgca gtgagtgcaa     1680

ccgcaccttc cccagccaca cggctctcaa acgccacctg cgctcacata caggcgacca     1740

cccctacgag tgtgagttct gtggcagctg cttccgggat gagagcacac tcaagagcca     1800

caaacgcatc cacacgggtg agaaacccta cgagtgcaat ggctgtggca agaagttcag     1860

cctcaagcat cagctggaga cgcactatag ggtgcacaca ggtgagaagc cctttgagtg     1920

taagctctgc caccagcgct cccgggacta ctcggccatg atcaagcacc tgagaacgca     1980

caacggcgcc tcgccctacc agtgcaccat ctgcacagag tactgcccca gcctctcctc     2040

catgcagaag cacatgaagg gccacaagcc cgaggagatc ccgcccgact ggaggataga     2100

gaagacgtac ctctacctgt gctatgtgtg aagggaggcc cgcggcggtg gagccgagcg     2160

gggagccagg aaagaagagt tggagtgaga tgaaggaagg actatgacaa ataaaaaagg     2220

aaaagaaaaa aaaaaacaga aggaaaagga aaaaaaaaaa aa                        2262


<210>  1221
<211>  8802
<212>  DNA
<213>  homo sapiens

<400>  1221
agttactgcc ctgacggcgg cggcggcggc ggttggccgg tgggggctgg ggcgagcacg       60

accgattctg ctgggaaagc tggaactggc agccgccggg ggccaagagg aggatccgga      120

gctgggagcg tgccccgggc ccggcggagg aggcggctgc agttggagtg gagtcttggg      180

agcgctgctg gcagcgactt ctcagcgaag caagtgtctg agactgagag tccctaacag      240

cggcagcggc ggccacggcg gcggctgggg ccgagttact tgtggaaatt gttgattacc      300

cggacgtctt aaaaccaaga aacctgtgaa caggttcatt aagaatctgc tgtcttgaaa      360

aatgcatatt atgaatgctt tgaattaaga aggtgttaac agtggttgtc atttctgcca      420

cataagagac tataatctga aacagttcct ggcagttgcc cagatgcctg aaactggcac      480

gatctagtac tcttgagtga tcatccttca acgagaaata cagagctact tacatactgt      540

acctcatacc gtataaatgt aatctctctg atgccattta atgcagtgga cctcttttca      600

gaatctaatt gtcagatgca gaattaacac ttggaatctg gagaagcatt ttgtacaaat      660

tgaaagattg ggttttttct ttagttttcc acatgtattg tctcatctct gttcttgaaa      720

catccacaat cacataaact ccagttataa ccatggagtt atgtgactca ttaaaattta      780

ggaaaagtgt tgctgagctg tggaatcagg cgtttctccc tcagttcaac aactaataca      840

tagactgctg atcaagaata aggaaccaaa taaagtcatg cacgttctgt tgacagagga      900

actctgtggc tgttgaattt tactgtaact agttactctg tcttcagagt caacttaata      960

tacaagttat gtcataatgg atggaaagac ctgtgttgat gtatccagac tctagcaaat     1020

gaagataaaa aacccgttat gactaatcct tgggaagaga aagtctgcaa aatggctcaa     1080

accagtttac tgcaagggaa gcagttttac tgtagggagt gggttttcca caagcttcag     1140

cattgcctcc aggagaaaag taactgctgc aatagtgctg tcaatgcacc atcacttgta     1200

atgaattctg ggaataatgc tagtggtgtc tctggaaagg gagctgcctg gggtgtgttg     1260

ttggtaggag ggcctggcag tggcaagacg gccctatgta ctgaactctt atggccaagt     1320

tcacctgcaa gtttgcagag aggtttacat cgccaagctt tggcctttca tttctgcaaa     1380

gcccaggact ctgatacttt gtgtgttgga gggtttatta gaggtctagt agcccagatc     1440

tgccgcagtg gactactcca aggatatgag gacaagctaa gggatccagc agtccaaagc     1500

ctcttacagc ctggggagtg cgagagaaac ccagccgaag catttaaaag gtgtgttcta     1560

ctccctcttc tgggaatgaa gcctccccag caaagcctat acctgcttgt tgattctgtt     1620

gatgaagggt gtaacattac tgaaggtgaa caaacgtcta ccagcttatc tgggactgtt     1680

gcagcacttt tagctggtca ccatgagttc tttccaccat ggctattgct tctctgttct     1740

gcccgaaagc agagtaaggc tgttactaaa atgtttactg gttttcgaaa aataagttta     1800

gatgaccttc ggaaggcata tatcgtcaag gatgttcagc agtacattct tcatcgttta     1860

gatcaagaag aagctttgcg acaacacctc acaaaagaaa ctgcagagat gttaaatcaa     1920

ctgcacatta aaagcagtgg atgctttctt tacctagaac gagttttaga tggagttgta     1980

gaaaatttta ttatgttaag agaaattcgt gacatcccag gaactctaaa tggtttatat     2040

ctctggctgt gccaaagact ttttgtaaga aaacaatttg caaaggttca gcctattttg     2100

aatgtgattc ttgcagcctg ccgacctttg accataacgg aattatatca cgcagtatgg     2160

accaaaaaca tgtcgttaac tttggaagat tttcaacgca agttagatat cctctccaaa     2220

cttcttgttg atggactagg aaatacaaaa atactgtttc attatagttt tgccgagtgg     2280

cttctggatg tgaaacactg tactcagaag tatttatgta atgcagcaga aggacacaga     2340

atgttggcta tgagttatac ctgtcaagcc aagaatttaa caccattgga agcacaagaa     2400

tttgcattgc acttaattaa ctcaaactta caattagaga cagcggagtt agctctgtgg     2460

atgatatgga atggtacacc tgtcagagat tccctttcta ctttgatacc caaggaacaa     2520

gaagtgctac agctgttggt taaagctggg gctcatgtca acagtgaaga cgatcgcaca     2580

tcatgcatag ttcgacaagc cttagaaaga gaggattcca ttcggacatt attagataat     2640

ggagcttcag taaatcagtg tgattcaaat gggagaacat tattggctaa tgctgcatat     2700

agtggcagtc ttgatgtagt caatttactt gtctctaggg gagcagattt agagatagaa     2760

gatgctcatg gacatacacc actcactcta gcggctagac agggacatac caaggtggtt     2820

aattgtttga ttgggtgtgg agcaaatatt aatcatactg atcaagatgg ttggacagca     2880

ttaagatctg ctgcttgggg tggccatact gaggtagttt ctgcactact ttatgctggc     2940

gtaaaagtgg attgtgcaga tgctgatagc cgaacagctt tgagagcagc agcatgggga     3000

ggacacgagg atattgtact gaatttgcta caacatggcg ctgaagtgaa caaagctgat     3060

aatgaaggta gaactgcttt gatagcagca gcatacatgg gacatagaga gattgtggaa     3120

cacctactgg accatggagc agaagtaaat catgaggatg ttgatggcag gactgcactc     3180

tctgtagctg cactttgtgt gcctgcaagt aaagggcacg catcagttgt tagcctttta     3240

attgatcgag gtgctgaagt agatcattgt gataaagatg gcatgactcc actgctggta     3300

gctgcctatg aaggacatgt tgatgtggtt gacttgcttc tagaaggggg agcagatgta     3360

gatcacacag ataacaatgg ccgtacaccc ctcttagcag cagcgtctat gggtcatgca     3420

tcagttgtaa atacactttt gttttggggt gcagctgtgg atagtattga tagtgaaggt     3480

aggacagtcc tcagtatagc ttcagcacaa ggaaatgttg aggtggtacg tactctactg     3540

gatagagggt tagatgaaaa tcacagagat gatgctggat ggacaccttt gcacatggca     3600

gcttttgaag ggcacagatt gatatgtgaa gcacttattg aacaaggtgc tagaacaaat     3660

gagattgaca atgatggacg aatccctttc atattagctt cacaagaggg tcattatgat     3720

tgtgttcaaa tattactgga aaacaaatcc aacattgatc aaagaggtta tgatggaaga     3780

aatgcactgc gggttgctgc attagaaggg cacagggaca ttgttgaatt gctttttagc     3840

catggtgctg atgttaactg caaagatgct gatggtcggc ctacacttta tatcttggcc     3900

ttagaaaatc agcttacaat ggccgaatat tttttagaaa atggtgcaaa cgtagaagca     3960

agtgatgctg aaggaaggac agcacttcat gtgtcttgtt ggcaaggcca tatggaaatg     4020

gtgcaggtcc tgatagcata ccatgctgac gtcaatgctg cagacaatga aaagcgctct     4080

gctttgcagt ctgcagcctg gcagggccat gtaaaagtgg ttcagcttct gattgagcat     4140

ggtgctgtag ttgaccatac atgtaaccaa ggtgcaactg cactctgtat tgcagcccag     4200

gaagggcaca ttgatgttgt tcaggtctta ttagagcatg gtgctgatcc aaaccatgct     4260

gatcaatttg gacgcactgc tatgcgtgtt gcagccaaaa atggacattc tcagataatt     4320

aaattattag aaaaatatgg tgcatctagt ttgaatggct gttccccatc tcctgttcac     4380

acaatggagc aaaaacctct acagtcattg tcttcaaaag tgcagtcatt aacaattaaa     4440

tcaaatagct ctggtagtac tggtggaggg gatatgcagc cttcgttacg tggtttacct     4500

aatgggccta ctcatgcttt tagttctcct tcagaatctc cagattctac agttgaccgg     4560

cagaagtcat cactgtcaaa taattccctg aaaagctcaa aaaattcatc tttgagaact     4620

acttcatcta cagcaacggc tcaaacagtg ccaattgata gctttcataa cttgtcattt     4680

acagaacaaa ttcagcagca ttcattgcca cgcagtagaa gtcgacagtc aattgtttcc     4740

ccatcttcca caacacagtc cttaggacag agtcataatt caccaagtag tgaatttgag     4800

tggagtcaag taaagcccag tttgaagtca actaaagcaa gtaaaggggg gaaatcagaa     4860

aattctgcca agtctggatc agctgggaaa aaagcgaaac aaagtaattc ttcacagcca     4920

aaggttttag aatatgaaat gactcagttt gatagaagag gacctatagc caaatccggg     4980

actgctgcac cacctaaaca aatgccagca gaatctcaat gcaaaattat gataccttca     5040

gctcagcagg aaattggtcg atctcaacag cagtttctta ttcaccaaca aagtggggaa     5100

cagaagaaga gaaatggaat aatgacaaat ccaaattatc atcttcagag caaccaggtt     5160

tttcttggta gggtttcagt cccacgaaca atgcaagata gagggcatca ggaagtgttg     5220

gagggatacc cttcctcaga gacagaatta agccttaaac aagctctgaa gcttcagatt     5280

gaaggttctg accctagctt caactataaa aaggaaacac cattataaaa gtttcctatt     5340

ctgtgaaaca gaagacattg tgatggagtg gttcttcagc tactggatgg aaacatatgc     5400

ctgttgattt gctgaaaaaa caaaaaaaat gaagaatgtg atctctgcag tacagttacc     5460

ttaattactg taatgtgcct aaatagtaag gctgccttct caatgtaacc ctctgtgctt     5520

aaaaaatttc attttgtgtg ctttgtattc actacacagg aataagcact ttttaaaaat     5580

gcagatacat actgcagttc cctgataaaa gctgaaaaga aaatttgagt attttaagtt     5640

aagatgtgat aaaaaatgtg catgtgccat aatcaaatat atatgaaaag gcagtgttcc     5700

ttgtatttat ttttttttct ttttgtggca aaagaaactt aaacatactg tttcagtcac     5760

attgcattgt agtgtatggc ctgtttcttg tatctttaaa gacgttgctc aataaaacaa     5820

atcttgcaac tgttctatgt tcactacacc ttcagcattg gataaaaatc attttctata     5880

taaatatcac attgaaatga aaaaatgatt tcttggcagt ttaaaaaaaa tattttatag     5940

tagtttaggg agctgcttta agtagtttaa atctggattt tcccagtaga attcttctca     6000

tctctggcta aacatgtcag aacaaacaac caaccagtct gtaggcagaa caaagtccta     6060

tttcatccgc tgggatacaa tttcatcttc cattcacttt gtcattccac ctctaagaag     6120

acagactatc attcctgagg catgaaaatt ctcagggaca aagccatgcc tcagtcacat     6180

gtgtgtgcag agagaaatgc acctgtctat ctaagggtag atttttgatc cctgaataat     6240

tcattgacta aactgacctc ttcctcctgg ctaaataaat taattttgct ggcttctctc     6300

tcagcggttt ctattttgta aattgctgca tgaccaaaat agccccactc aaaatcaatt     6360

ggattaattt taatggtttg gttggatgaa tattctggat gaatataaaa tgtgctgccc     6420

ttcacagatg acaccactcc cctgtcaatc atagcacatg tgtacttttt attgttactt     6480

aatagtgatg gatttgcact tttctatcct catactcttt cctgttttct tctttgtaca     6540

attgcatgca ggagggctgg atgccagggt taagagagaa attcatgaca aggaaggtaa     6600

aattggttca aatgagcatg tgtcccacag ccttagtctc cttactctta aatcagtgga     6660

gctgtagctt agatgggtcg tttatatgtc tggaaaagtt gtcataacag tttagaagcc     6720

aaggttgtgg atttgatctt agaatgggcc tgttaatctt atagaaccca gaaattctgt     6780

tcttttcatg tactgttgat gaggaatgag gaaagagaat ttggagattc agcacaaaac     6840

cattgctact tctagaacaa aatctttaga atatgtccta ataacaaagg tcagtaatgt     6900

catcttcata tatgaaggac acatgtgata cattgttcgt ggaaatagaa atgtataatt     6960

atgataaatg tttcacttga atcttattgt aaggcttttc ttgcttttat tttttaaagt     7020

cagcaaaact cattttgtct gtcatctata agtcatagtg aggactacga gataagttga     7080

taagttcaat tgatattaag gtgacatggc aatattaata actcaaatgt gaatgtttca     7140

agtattgaat tcttgtccct atgggacatt tattaaataa aattaatggg actcttgcaa     7200

agtagcctta aaagtgttaa tgagtctatt aataaatatg aacacatact attattagaa     7260

ccaactttac tcatatctca aatacagtac atttacatta ctgtagagga tgaagctcta     7320

atttctatta catgtaattt tctttagaaa gagaaccctg aaagctgcca gtttttctat     7380

taactttgaa ttattgaaat tgtatttatt taattttatt gtttttacaa aattgcacct     7440

tgtgtccaaa gggcgaagat atgacattgc ataagggatt tatgtttttc aaagagctaa     7500

ctgttttcat atccatacta tatacacttg aagcaattgg taggaagaga acctattgga     7560

aaaatacgat tttcaaaagt aagtattcct cgggatgttt ttatataaat tatgttttgg     7620

aatagaacat aaatgacttt gagttaggat aaggatgata ggatgggtgc tggagatgcc     7680

ctgccttgct tatttgtttc tgtgggggat ttaatactat aaatgaaaat ggcttctgct     7740

ccattaaaaa gtaaaaattg tcctccaaat ataaaactcc ttaatagata tttttgaaat     7800

taaaatcttt aaattttata aatcagctgt tgccactaca caactatgat ggcatgtgct     7860

tataacattt ttataacatt ccgtctgtgt ctattcccta aatatcatga gtttataata     7920

aggaaagtga taaaaataca gtaatgaaat aaaaatctga atgtttctaa gaaaggtttt     7980

ggaaggaaaa atgacctgaa atcagtgcgt actgcaaagt acagccaata atttttgttc     8040

tttgttttca cccccaccct cactggaatt ctcaccaaaa atagtttgat acttaaaaaa     8100

cagaagtaaa tacttttctc aatattgttt tggctatgca aatatttgtt ttgcttaatg     8160

tcctccattt acacttctca gcaaatgtag ttgcaaacaa atgctttctt tttatttttc     8220

ccttggtttg aggtatgtaa atagccaaaa atgtacattg aatttcacat tgtaaaagtt     8280

ttattttatc ccttgtatga tattactcaa aaaatccctg tgtatatgaa agtgcataat     8340

aaatatattt gctttacaga gaagatcttg ttttaatttt gtccttgaac cagtagaaca     8400

tgcatgatat gcatatagca taaacaactg ttagttgttt taagttatta tcttaaataa     8460

atcctgagca aatgaatttg gaaacatttt gcaaagaaga aagtgaaata taacactgtc     8520

caaaggaagg tagaaaaaca aagatttact gtttatgtct tcctaagcct ttttaaagac     8580

ttaatgttct tttccccccc gtgactgatt atatactata tcacaccatg tcaggttttg     8640

tgcctctgag aattgcagta atccaataac ttttgtatat gtgtgctcct tgatcatcag     8700

aatattatgg ccatcttatg gcggatattt tgggagttta ttgcaaacat ggtcattcat     8760

tttctaaata aaatttgtgt gtttcttcac tcagtaaaaa aa                        8802


<210>  1222
<211>  1507
<212>  DNA
<213>  homo sapiens

<400>  1222
agatgtcaaa ggctgaagct gctccctttg ccacattata actagtaggg gatcctcacc       60

gaccatggcc acagctgcct cgaatcccta cagcattctc agttccacct ccctagtcca      120

tgcggactct gcgggcatgc agcaggggag tcctttccgc aaccctcaga aacttctcca      180

aagtgattac ttgcagggag ttcccagcaa tgggcatccc ctcgggcatc actgggtgac      240

cagtctgagc gacgggggcc catggtcctc cacactggcc accagccccc tggaccagca      300

ggacgtgaag cccgggcgcg aagacctgca actgggtgcg atcatccatc accgctcgcc      360

acacgtagcc caccactcac cgcacactaa ccaccccaac gcctgggggg ccagcccggc      420

accgaacccg tctatcacgt caagcggcca acccctcaac gtgtactcgc agcctggctt      480

caccgtgagc ggcatgctgg aacacggggg actcacccca cctccagctg ccgcctctgc      540

acagagcctg cacccggtgc tccgagagcc cccggatcac ggcgaactgg gctcgcacca      600

ttgccaggat cactccgacg aggagacgcc aacctctgat gagttggaac agttcgccaa      660

acaattcaaa caaagaagaa tcaagttggg cttcacgcag gccgacgtgg ggttggcgct      720

gggcacactg tatggtaacg tgttctcgca gaccaccatc tgcaggttcg aggccttgca      780

gctgagcttc aaaaatatgt gcaagctgaa gcccctgctg aacaagtggc tggaggaggc      840

ggattcgtcc acagggagcc cgaccagcat tgacaagatc gctgcacagg gccgcaagcg      900

caagaagcgg acctccatcg aggtgagtgt caagggcgta ctggagacgc atttcctcaa      960

gtgtcccaag cctgccgcgc aggagatctc ctcgctggca gacagcctcc agttggagaa     1020

ggaagtggtg cgtgtctggt tctgtaatcg aagacaaaaa gagaaaagaa tgactccgcc     1080

aggggatcag cagccgcatg aggtttattc gcacaccgtg aaaacagaca catcttgcca     1140

tgatctctga ctggaggaag cgaggaggcg gccggccgca ctgggagcag cgcggatttc     1200

tctttctctc tcactctctt cctttcattc tagtattctt tattattttt ctctctctct     1260

cgttcgctcg ctctctcgta ctctctctct tttccctcct ttcctttttc tttcctttcc     1320

cctttttctt tcccttcttt ttccctttcc tttcctttca ttttctttcc tttccccttc     1380

ccttcccttc ccttccatct cttcctttcc tttcctttct tttcttttgc tttcctttcc     1440

tttttttccc ttttctttcc ttttcataag aggttctaac ttctgttgac aaaggaaaca     1500

catactc                                                               1507


<210>  1223
<211>  2535
<212>  DNA
<213>  homo sapiens

<400>  1223
gcactgcctc tggcacctgg ggcagccgcg cccgcggagt tttccgcccg gcgctgacgg       60

ctgctgcgcc cgcggctccc cagtgccccg agtgccccgc gggccccgcg agcgggagtg      120

ggacccagcc cctaggcaga acccaggcgc cgcgcccggg acgcccgcgg agagagccac      180

tcccgcccac gtcccatttc gcccctcgcg tccggagtcc ccgtggccag gtgtgtgtct      240

ggggaagaga cttacagaag tggagttgct gagtcaaaga tctaaccatg agctaccctg      300

gctatccccc gcccccaggt ggctacccac cagctgcacc aggtggtggt ccctggggag      360

gtgctgccta ccctcctccg cccagcatgc cccccatcgg gctggataac gtggccacct      420

atgcggggca gttcaaccag gactatctct cgggaatggc ggccaacatg tctgggacat      480

ttggaggagc caacatgccc aacctgtacc ctggggcccc tggggctggc tacccaccag      540

tgccccctgg cggctttggg cagcccccct ctgcccagca gcctgttcct ccctatggga      600

tgtatccacc cccaggagga aacccaccct ccaggatgcc ctcatatccg ccatacccag      660

gggcccctgt gccgggccag cccatgccac cccccggaca gcagccccca ggggcctacc      720

ctgggcagcc accagtgacc taccctggtc agcctccagt gccactccct gggcagcagc      780

agccagtgcc gagctaccca ggatacccgg ggtctgggac tgtcaccccc gctgtgcccc      840

caacccagtt tggaagccga ggcaccatca ctgatgctcc cggctttgac cccctgcgag      900

atgccgaggt cctgcggaag gccatgaaag gcttcgggac ggatgagcag gccatcattg      960

actgcctggg gagtcgctcc aacaagcagc ggcagcagat cctactttcc ttcaagacgg     1020

cttacggcaa ggatttgatc aaagatctga aatctgaact gtcaggaaac tttgagaaga     1080

caatcttggc tctgatgaag accccagtcc tctttgacat ttatgagata aaggaagcca     1140

tcaagggggt tggcactgat gaagcctgcc tgattgagat cctcgcttcc cgcagcaatg     1200

agcacatccg agaattaaac agagcctaca aagcagaatt caaaaagacc ctggaagagg     1260

ccattcgaag cgacacatca gggcacttcc agcggctcct catctctctc tctcagggaa     1320

accgtgatga aagcacaaac gtggacatgt cactcgccca gagagatgcc caggagctgt     1380

atgcggccgg ggagaaccgc ctgggaacag acgagtccaa gttcaatgcg gttctgtgct     1440

cccggagccg ggcccacctg gtagcagttt tcaatgagta ccagagaatg acaggccggg     1500

acattgagaa gagcatctgc cgggagatgt ccggggacct ggaggagggc atgctggccg     1560

tggtgaaatg tctcaagaat accccagcct tctttgcgga gaggctcaac aaggccatga     1620

ggggggcagg aacaaaggac cggaccctga ttcgcatcat ggtgtctcgc agcgagaccg     1680

acctcctgga catcagatca gagtataagc ggatgtacgg caagtcgctg taccacgaca     1740

tctcgggaga tacttcaggg gattaccgga agattctgct gaagatctgt ggtggcaatg     1800

actgaacagt gactggtggc tcacttctgc ccacctgccg gcaacaccag tgccaggaaa     1860

aggccaaaag aatgtctgtt tctaacaaat ccacaaatag ccccgagatt caccgtccta     1920

gagcttaggc ctgtcttcca cccctcctga cccgtatagt gtgccacagg acctgggtcg     1980

gtctagaact ctctcaggat gccttttcta ccccatccct cacagcctct tgctgctaaa     2040

atagatgttt catttttctg actcatgcaa tcattcccct ttgcctgtgg ctaagacttg     2100

gcttcatttc gtcatgtaat tgtatatttt tatttggagg catattttct tttcttacag     2160

tcattgccag acagaggcat acaagtctgt ttgctgcata cacatttctg gtgagggcga     2220

ctgggtgggt gaagcaccgt gtcctcgctg aggagagaaa gggaggcgtg cctgagaagg     2280

tagcctgtgc atctggtgag tgtgtcacga gctttgttac tgccaaactc actccttttt     2340

agaaaaaaca aaaaaaaagg gccagaaagt cattccttcc atcttccttg cagaaaccac     2400

gagaacaaag ccagttccct gtcagtgaca gggcttcttg taatttgtgg tatgtgcctt     2460

aaacctgaat gtctgtagcc aaaacttgtt tccacattaa gagtcagcca gctctggaat     2520

ggtctggaaa tgtca                                                      2535


<210>  1224
<211>  657
<212>  DNA
<213>  homo sapiens

<400>  1224
gcttgctgat gggtccgggt ggggcgcgcg tggactatgg gcccgggagg tcccttactg       60

tccccgagcc gcgggttcct cttgtgcaaa acggggtggc actccaatcg cctgcttggt      120

gattgtggcc cccacacacc tgtttctaca gcgcttagct tcatcgcagt aggaatggca      180

gccccatcta tgaaggaaag acaggtctgc tggggggccc gggatgagta ctggaagtgt      240

ttagatgaga acttagagga tgcttctcaa tgcaagaagt taagaagctc tttcgaatca      300

agttgtcccc aacagtggat aaaatatttt gataaaagaa gagactactt aaaattcaaa      360

gaaaaatttg aagcaggaca atttgagcct tcagaaacaa ctgcaaaatc ctaggctgtt      420

cataaagatt gaaagtattc tttctggaca ttgaaaaagc tccactgact atggaacagt      480

aatagtttga atcatagtga acatcaatac ttgttcccta tatacgacac ttgataatta      540

agatgatcaa gaaccagaag atctgtgaag aaatgaaata aaatggtatt tagtaagaaa      600

tctctatttt aagaaaaaaa gtaaaacctg ttataaacac atgcaaaaaa aaaaaaa         657


<210>  1225
<211>  2324
<212>  DNA
<213>  homo sapiens

<400>  1225
atctctcagc gcagcaggac acggggacca tgcaagctgt aattggtcag gcatgaactc       60

tcttgggttg tgttaccctg tttgctgttt actgtcaaga tgctgaaaga atgttcttat      120

aatgatccaa gaggaagtgg caaatgagtg ctcttcttca ggatccaatg atagctggac      180

aagtcagtaa gcccttgctg tcagtgcgga gtgaaatgaa tgcggagttg agaggtgagg      240

acaaggctgc tacttcagac agcgagctga atgagcccct gcttgcgcct gtggaatcaa      300

atgacagcga ggacactccc agcaagctct tcggggctag aggaaaccca gcattatcag      360

acccaggcac tcctgaccaa caccaggcca gtcagaccca ccccccattt ccagttgggc      420

cacagccact tctgacggca cagcagttag cttctgctgt ggccggcgtg atgccgggag      480

gccccccagc cctcaaccag ccaatcctca ttcccttcaa catggcggga cagctaggag      540

gccagcaagg actggttctc acactgccaa cagcgaatct caccaacatc caagggctgg      600

tggcagcagc tgcagccgga ggcattatga ctctgccact gcaaaatcta caagctacct      660

catccctgaa ctcccagctc cagcagctcc agctccagct ccagcagcag cagcagcagc      720

agcagcagca gcctcccccg tcaaccaacc agcacccgca accagcccca caggcgccct      780

cgcagtccca gcagcagccg ctgcagccca ccccacccca gcagccacca cccgcctctc      840

agcagccgcc agctcctaca tctcagctgc aacaggcgcc tcagccccag cagcaccaac      900

cccactccca ctcccagaac cagaaccaac catctccaac ccagcagagc tccagccccc      960

cgcagaaacc tagtcagtct ccaggacatg gcctgccttc accgctcacg ccacccaatc     1020

ctctacagct ggttaataat ccactagcaa gtcaggctgc agcggctgca gcagccatga     1080

gctccatagc aagctcacag gcctttggca atgccctctc cagtcttcag ggggtcacag     1140

gtcaactagt tactaatgca caaggacaga ttatcgggac cattccactg atgcctaatc     1200

cagggccatc gagccaagca gcaagcggca ctcagggctt gcaagtgcag ccaatcaccc     1260

cccagctcct cacaaacgcc cagggccaga tcatcgccac agtcattggg aaccagatcc     1320

tgcccgtgat caacacccag ggcatcacgc tgtcacccat caagcccggc cagcagctcc     1380

accaaccctc ccagacgtca gtgggtcaag cagcctccca aggcaacctt ctgcacctgg     1440

ctcacagcca agcatccatg tctcaaagtc ccgtccggca ggcttcctct tcttcctcct     1500

catcctcctc ttcttcagct ttgagcgtgg gccagttagt cagcaatcct caaacggcag     1560

cgggtgaggt ggatggggtt aatctggagg agatccgaga atttgccaaa gcttttaaaa     1620

tccggcgcct gtcccttggc ctgacccaga ctcaggtggg acaggctctc agtgctacag     1680

agggccccgc gtacagccag tcggccatct gcagacacac catcctgaga agccactttt     1740

tcctaccaca ggaagcccaa gagaacacta tagctagcag tctgacagcc aaactgaacc     1800

ctggcctttt gtatcctgcc aggtttgaaa agctggacat cacccctaaa agtgcccaga     1860

agatcaagcc ggtgcttgag cggtggatgg ctgaggctga ggcccgccat cgagcaggta     1920

tgcagaacct gaccgagttt atcgggagtg aaccatccaa aaagcgcaag cggcgcacct     1980

ccttcacacc ccaggccctt gagatcctca atgcccactt tgagaagaac acacaccctt     2040

ctgggcagga aatgaccgaa attgctgaga agctgaacta tgaccgagaa gtagttagag     2100

tttggttctg caataagagg caagccctga agaacacaat taaacgctta aaacagcacg     2160

agccggccac ggcagtccct ttggagccct taacagactc tctggaagaa aactcctaaa     2220

gagatgccca cccataatca gaagcaaaat tcacagaaac taaactccac ccttgggact     2280

ccacaacaac aacaacaaca aaatttaatt taatttaaaa atag                      2324


<210>  1226
<211>  2105
<212>  DNA
<213>  homo sapiens

<400>  1226
agactccgcc caagcatgca cacacacagg cttgatgctc gctcccgttt ctacaggagg       60

ttttgacggc tggatgctgc agggcatccc ctcgcctgga ggaggttcac ttgtggccag      120

gttcccagca cacccacttg ctcactgggg ccctggggac accgccacac tcgagcccat      180

cctacggcct caatccttac cagtccccag gccatggact gccacactgt aggtcttcaa      240

tcaaggttca gtggagtttc gaatgtacac acaccctgaa agacagcgcg gccacctcag      300

aaaacaacgc gcgcccagct ggctcccctc cgacagggcc cacggctact gggtcggcct      360

cctccggacc ctgagcacag cctggtatgc gtgcgggctc ggaatacgga tctgagcaga      420

agaaatgcga gtggagagcg gttctgcgca ggaaagagga attttgttgg aaagcctgtc      480

gacgttgcta gaaaagacca cagcatctca cgaggggcgt gcgccgggaa accgggagtt      540

gacggacctc ctgccccccg aggtctgcag tctcctgaac ccagcagcca tctacgccaa      600

caacgagatc agcctgcgtg acgttgaggt ctacggcttt gactacgact acaccctggc      660

ccagtatgca gacgcactgc accccgagat cttcagtacc gcccgtgaca tcctgatcga      720

gcactacaag tacccagaag ggattcggaa gtatgactac aaccccagct ttgccatccg      780

tggcctccac tatgacattc agaagagcct tctgatgaag attgacgcct tccactacgt      840

gcagctgggg acagcctaca ggggcctcca gcctgtgcca gacgaggagg tgattgagct      900

gtatgggggt acccagcaca tcccactata ccagatgagt ggcttctatg gcaagggtcc      960

ctccattaag cagttcatgg acatcttctc gctaccggag atggctctgc tgtcctgtgt     1020

ggtggactac tttctgggcc acagcctgga gtttgaccaa gcacatctct acaaggacgt     1080

gacggacgcc atccgagacg tgcatgtgaa gggcctcatg taccagtgga tcgagcagga     1140

catggagaag tacatcctga gaggggatga gacgtttgct gtcctgagcc gcctggtggc     1200

ccatgggaaa cagctgttcc tcatcaccaa cagtcctttc agcttcgtag acaaggggat     1260

gcggcacatg gtgggtcccg attggcgcca gctcttcgat gtggtcattg tccaggcaga     1320

caagcccagc ttcttcactg accggcgcaa gcctttcaga aaactcgatg agaagggctc     1380

acttcagtgg gaccggatca cccgcttgga aaagggcaag atctatcggc agggaaacct     1440

gtttgacttc ttacgcttga cggaatggcg tggcccccgc gtgctctact tcggggacca     1500

cctctatagt gatctggcgg atctcatgct gcggcacggc tggcgcacag gcgccatcat     1560

ccccgagctg gagcgtgaga tccgcatcat caacacggag cagtacatgc actcgctgac     1620

gtggcagcag gcgctcacgg ggctgctgga gcgcatgcag acctatcagg acgcggagtc     1680

gaggcaggtg ctggctgcct ggatgaaaga gcggcaggag ctgaggtgca tcaccaaggc     1740

cctgttcaat gcgcagttcg gcagcatctt ccgcaccttc cacaacccca cctacttctc     1800

aaggcgcctc gtgcgcttct ctgacctcta catggcctcc ctcagctgcc tgctcaacta     1860

ccgcgtggac ttcaccttct acccacgccg tacgccgctg cagcacgagg cacccctctg     1920

gatggaccag ctctgcaccg gctgcatgaa gacccccttc cttggtgaca tggcccacat     1980

ccgctgaggg cacctttatt gtctgggaca ggccctcagc ccctcctgcc ccatccaccc     2040

agacaagcaa taaaagtggt ctcctccctg tgcatgcttc tgctttcaaa aaaaaaaaaa     2100

aaaaa                                                                 2105


<210>  1227
<211>  1832
<212>  DNA
<213>  homo sapiens

<400>  1227
ggccgagggc agcgcgggcg gcgggcggcg cgcggtgggc atggcgggtg cggggctgcg       60

ggcggccgct cggcgctggc tgctgtgcgg aggccacggc gggccgcgag ccgcctcgtc      120

ctcgccctcc tgccctgggt gcggcccccc gggtcccggc gcccactgcc ccggcgtccc      180

gcgctccgcg cccgcccagg cacccaccag cggcgccgac ctcagcgcgc acctatgggc      240

tcgctaccag gacatgcgga gactggtgca cgacctcctg ccccccgagg tctgcagtct      300

cctgaaccca gcagccatct acgccaacaa cgagatcagc ctgcgtgacg ttgaggtcta      360

cggctttgac tacgactaca ccctggccca gtatgcagac gcactgcacc ccgagatctt      420

cagtaccgcc cgtgacatcc tgatcgagca ctacaagtac ccagaaggga ttcggaagta      480

tgactacaac cccagctttg ccatccgtgg cctccactat gacattcaga agagccttct      540

gatgaagatt gacgccttcc actacgtgca gctggggaca gcctacaggg gcctccagcc      600

tgtgccagac gaggaggtga ttgagctgta tgggggtacc cagcacatcc cactatacca      660

gatgagtggc ttctatggca agggtccctc cattaagcag ttcatggaca tcttctcgct      720

accggagatg gctctgctgt cctgtgtggt ggactacttt ctgggccaca gcctggagtt      780

tgaccaagca catctctaca aggacgtgac ggacgccatc cgagacgtgc atgtgaaggg      840

cctcatgtac cagtggatcg agcaggacat ggagaagtac atcctgagag gggatgagac      900

gtttgctgtc ctgagccgcc tggtggccca tgggaaacag ctgttcctca tcaccaacag      960

tcctttcagc ttcgtagaca aggggatgcg gcacatggtg ggtcccgatt ggcgccagct     1020

cttcgatgtg gtcattgtcc aggcagacaa gcccagcttc ttcactgacc ggcgcaagcc     1080

tttcagaaaa ctcgatgaga agggctcact tcagtgggac cggatcaccc gcttggaaaa     1140

gggcaagatc tatcggcagg gaaacctgtt tgacttctta cgcttgacgg aatggcgtgg     1200

cccccgcgtg ctctacttcg gggaccacct ctatagtgat ctggcggatc tcatgctgcg     1260

gcacggctgg cgcacaggcg ccatcatccc cgagctggag cgtgagatcc gcatcatcaa     1320

cacggagcag tacatgcact cgctgacgtg gcagcaggcg ctcacggggc tgctggagcg     1380

catgcagacc tatcaggacg cggagtcgag gcaggtgctg gctgcctgga tgaaagagcg     1440

gcaggagctg aggtgcatca ccaaggccct gttcaatgcg cagttcggca gcatcttccg     1500

caccttccac aaccccacct acttctcaag gcgcctcgtg cgcttctctg acctctacat     1560

ggcctccctc agctgcctgc tcaactaccg cgtggacttc accttctacc cacgccgtac     1620

gccgctgcag cacgaggcac ccctctggat ggaccagctc tgcaccggct gcatgaagac     1680

ccccttcctt ggtgacatgg cccacatccg ctgagggcac ctttattgtc tgggacaggc     1740

cctcagcccc tcctgcccca tccacccaga caagcaataa aagtggtctc ctccctgtgc     1800

atgcttctgc tttcaaaaaa aaaaaaaaaa aa                                   1832


<210>  1228
<211>  2105
<212>  DNA
<213>  homo sapiens

<400>  1228
agactccgcc caagcatgca cacacacagg cttgatgctc gctcccgttt ctacaggagg       60

ttttgacggc tggatgctgc agggcatccc ctcgcctgga ggaggttcac ttgtggccag      120

gttcccagca cacccacttg ctcactgggg ccctggggac accgccacac tcgagcccat      180

cctacggcct caatccttac cagtccccag gccatggact gccacactgt aggtcttcaa      240

tcaaggttca gtggagtttc gaatgtacac acaccctgaa agacagcgcg gccacctcag      300

aaaacaacgc gcgcccagct ggctcccctc cgacagggcc cacggctact gggtcggcct      360

cctccggacc ctgagcacag cctggtatgc gtgcgggctc ggaatacgga tctgagcaga      420

agaaatgcga gtggagagcg gttctgcgca ggaaagagga attttgttgg aaagcctgtc      480

gacgttgcta gaaaagacca cagcatctca cgaggggcgt gcgccgggaa accgggagtt      540

gacggacctc ctgccccccg aggtctgcag tctcctgaac ccagcagcca tctacgccaa      600

caacgagatc agcctgcgtg acgttgaggt ctacggcttt gactacgact acaccctggc      660

ccagtatgca gacgcactgc accccgagat cttcagtacc gcccgtgaca tcctgatcga      720

gcactacaag tacccagaag ggattcggaa gtatgactac aaccccagct ttgccatccg      780

tggcctccac tatgacattc agaagagcct tctgatgaag attgacgcct tccactacgt      840

gcagctgggg acagcctaca ggggcctcca gcctgtgcca gacgaggagg tgattgagct      900

gtatgggggt acccagcaca tcccactata ccagatgagt ggcttctatg gcaagggtcc      960

ctccattaag cagttcatgg acatcttctc gctaccggag atggctctgc tgtcctgtgt     1020

ggtggactac tttctgggcc acagcctgga gtttgaccaa gcacatctct acaaggacgt     1080

gacggacgcc atccgagacg tgcatgtgaa gggcctcatg taccagtgga tcgagcagga     1140

catggagaag tacatcctga gaggggatga gacgtttgct gtcctgagcc gcctggtggc     1200

ccatgggaaa cagctgttcc tcatcaccaa cagtcctttc agcttcgtag acaaggggat     1260

gcggcacatg gtgggtcccg attggcgcca gctcttcgat gtggtcattg tccaggcaga     1320

caagcccagc ttcttcactg accggcgcaa gcctttcaga aaactcgatg agaagggctc     1380

acttcagtgg gaccggatca cccgcttgga aaagggcaag atctatcggc agggaaacct     1440

gtttgacttc ttacgcttga cggaatggcg tggcccccgc gtgctctact tcggggacca     1500

cctctatagt gatctggcgg atctcatgct gcggcacggc tggcgcacag gcgccatcat     1560

ccccgagctg gagcgtgaga tccgcatcat caacacggag cagtacatgc actcgctgac     1620

gtggcagcag gcgctcacgg ggctgctgga gcgcatgcag acctatcagg acgcggagtc     1680

gaggcaggtg ctggctgcct ggatgaaaga gcggcaggag ctgaggtgca tcaccaaggc     1740

cctgttcaat gcgcagttcg gcagcatctt ccgcaccttc cacaacccca cctacttctc     1800

aaggcgcctc gtgcgcttct ctgacctcta catggcctcc ctcagctgcc tgctcaacta     1860

ccgcgtggac ttcaccttct acccacgccg tacgccgctg cagcacgagg cacccctctg     1920

gatggaccag ctctgcaccg gctgcatgaa gacccccttc cttggtgaca tggcccacat     1980

ccgctgaggg cacctttatt gtctgggaca ggccctcagc ccctcctgcc ccatccaccc     2040

agacaagcaa taaaagtggt ctcctccctg tgcatgcttc tgctttcaaa aaaaaaaaaa     2100

aaaaa                                                                 2105


<210>  1229
<211>  1843
<212>  DNA
<213>  homo sapiens

<400>  1229
gcggaatggg gcgggacttc cagtaggagg cggcaagttt gaaaagtgat gacggttgac       60

gtttgctgat ttttgacttt gcttgtagct gctccccgaa ctcgccgtct tcctgtcggc      120

ggccggcact gtagattaac aggaaacttc caagatggaa actttgtctt tccccagata      180

taatgtagct gagattgtga ttcatattcg caataagatc ttaacaggag ctgatggtaa      240

aaacctcacc aagaatgatc tttatccaaa tccaaagcct gaagtcttgc acatgatcta      300

catgagagcc ttacaaatag tatatggaat tcgactggaa catttttaca tgatgccagt      360

gaactctgaa gtcatgtatc cacatttaat ggaaggcttc ttaccattca gcaatttagt      420

tactcatctg gactcatttt tgcctatctg ccgggtgaat gactttgaga ctgctgatat      480

tctatgtcca aaagcaaaac ggacaagtcg gtttttaagt ggcattatca actttattca      540

cttcagagaa gcatgccgtg aaacgtatat ggaatttctt tggcaatata aatcctctgc      600

ggacaaaatg caacagttaa acgccgcaca ccaggaggca ttaatgaaac tggagagact      660

tgattctgtt ccagttgaag agcaagaaga gttcaagcag ctttcagatg gaattcagga      720

gctacaacaa tcactaaatc aggattttca tcaaaaaacg atagtgctgc aagagggaaa      780

ttcccaaaag aagtcaaata tttcagagaa aaccaagcgt ttgaatgaac taaaattgtc      840

ggtggtttct ttgaaagaaa tacaagagag tttgaaaaca aaaattgtgg attctccaga      900

gaagttaaag aattataaag aaaaaatgaa agatacggtc cagaagctta aaaatgccag      960

acaagaagtg gtggagaaat atgaaatcta tggagactca gttgactgcc tgccttcatg     1020

tcagttggaa gtgcagttat atcaaaagaa aatacaggac ctttcagata atagggaaaa     1080

attagccagt atcttaaagg agagcctgaa cttggaggac caaattgaga gtgatgagtc     1140

agaactgaag aaattgaaga ctgaagaaaa ttcgttcaaa agactgatga ttgtgaagaa     1200

ggaaaaactt gccacagcac aattcaaaat aaataagaag catgaagatg ttaagcaata     1260

caaacgcaca gtaattgagg attgcaataa agttcaagaa aaaagaggtg ctgtctatga     1320

acgagtaacc acaattaatc aagaaatcca aaaaattaaa cttggaattc aacaactaaa     1380

agatgctgct gaaagggaga aactgaagtc ccaggaaata tttctaaact tgaaaactgc     1440

tttggagaaa taccacgacg gtattgaaaa ggcagcagag gactcctatg ctaagataga     1500

tgagaagaca gctgaactga agaggaagat gttcaaaatg tcaacctgat taacaaaatt     1560

acatgtcttt ttgtaaatgg cttgccatct tttaattttc tatttagaaa gaaaagttga     1620

agcgaatgga agtatcagaa gtaccaaata atgttggctt catcagtttt tatacactct     1680

cataagtagt taataagatg aatttaatgt aggcttttat taatttataa ttaaaataac     1740

ttgtgcagct attcatgtct ctactctgcc ccttgttgta aatagtttga gtaaaacaaa     1800

actagttacc tttgaaatat atatattttt ttctgttact atc                       1843


<210>  1230
<211>  1989
<212>  DNA
<213>  homo sapiens

<400>  1230
gcggaatggg gcgggacttc cagtaggagg cggcaagttt gaaaagtgat gacggttgac       60

gtttgctgat ttttgacttt gcttgtagct gctccccgaa ctcgccgtct tcctgtcggc      120

ggccggcact gtaggtgagc gcgagaggac ggaggaagga agcctgcaga cagacgcctt      180

ctccatccca aggcgcgggc aggtgccggg acgctgggcc tggcggtgtt ttcgtcgtgc      240

tcagcggtgg gaggaggcgg aagaaaccag agcctgggag attaacagga aacttccaag      300

atggaaactt tgtctttccc cagatataat gtagctgaga ttgtgattca tattcgcaat      360

aagatcttaa caggagctga tggtaaaaac ctcaccaaga atgatcttta tccaaatcca      420

aagcctgaag tcttgcacat gatctacatg agagccttac aaatagtata tggaattcga      480

ctggaacatt tttacatgat gccagtgaac tctgaagtca tgtatccaca tttaatggaa      540

ggcttcttac cattcagcaa tttagttact catctggact catttttgcc tatctgccgg      600

gtgaatgact ttgagactgc tgatattcta tgtccaaaag caaaacggac aagtcggttt      660

ttaagtggca ttatcaactt tattcacttc agagaagcat gccgtgaaac gtatatggaa      720

tttctttggc aatataaatc ctctgcggac aaaatgcaac agttaaacgc cgcacaccag      780

gaggcattaa tgaaactgga gagacttgat tctgttccag ttgaagagca agaagagttc      840

aagcagcttt cagatggaat tcaggagcta caacaatcac taaatcagga ttttcatcaa      900

aaaacgatag tgctgcaaga gggaaattcc caaaagaagt caaatatttc agagaaaacc      960

aagcgtttga atgaactaaa attgtcggtg gtttctttga aagaaataca agagagtttg     1020

aaaacaaaaa ttgtggattc tccagagaag ttaaagaatt ataaagaaaa aatgaaagat     1080

acggtccaga agcttaaaaa tgccagacaa gaagtggtgg agaaatatga aatctatgga     1140

gactcagttg actgcctgcc ttcatgtcag ttggaagtgc agttatatca aaagaaaata     1200

caggaccttt cagataatag ggaaaaatta gccagtatct taaaggagag cctgaacttg     1260

gaggaccaaa ttgagagtga tgagtcagaa ctgaagaaat tgaagactga agaaaattcg     1320

ttcaaaagac tgatgattgt gaagaaggaa aaacttgcca cagcacaatt caaaataaat     1380

aagaagcatg aagatgttaa gcaatacaaa cgcacagtaa ttgaggattg caataaagtt     1440

caagaaaaaa gaggtgctgt ctatgaacga gtaaccacaa ttaatcaaga aatccaaaaa     1500

attaaacttg gaattcaaca actaaaagat gctgctgaaa gggagaaact gaagtcccag     1560

gaaatatttc taaacttgaa aactgctttg gagaaatacc acgacggtat tgaaaaggca     1620

gcagaggact cctatgctaa gatagatgag aagacagctg aactgaagag gaagatgttc     1680

aaaatgtcaa cctgattaac aaaattacat gtctttttgt aaatggcttg ccatctttta     1740

attttctatt tagaaagaaa agttgaagcg aatggaagta tcagaagtac caaataatgt     1800

tggcttcatc agtttttata cactctcata agtagttaat aagatgaatt taatgtaggc     1860

ttttattaat ttataattaa aataacttgt gcagctattc atgtctctac tctgcccctt     1920

gttgtaaata gtttgagtaa aacaaaacta gttacctttg aaatatatat atttttttct     1980

gttactatc                                                             1989


<210>  1231
<211>  1820
<212>  DNA
<213>  homo sapiens

<400>  1231
ggcgctgggc ggctgcggcg cgcggtgcgc ggtgcgtagt ctggagctat ggtggtggtg       60

gcagccgcgc cgaacccggc cgacgggacc cctaaagttc tgcttctgtc ggggcagccc      120

gcctccgccg ccggagcccc ggccggccag gccctgccgc tcatggtgcc agcccagaga      180

ggggccagcc cggaggcagc gagcgggggg ctgccccagg cgcgcaagcg acagcgcctc      240

acgcacctga gccccgagga gaaggcgctg aggaggaaac tgaaaaacag agtagcagct      300

cagactgcca gagatcgaaa gaaggctcga atgagtgagc tggaacagca agtggtagat      360

ttagaagaag agaaccaaaa acttttgcta gaaaatcagc ttttacgaga gaaaactcat      420

ggccttgtag ttgagaacca ggagttaaga cagcgcttgg ggatggatgc cctggttgct      480

gaagaggagg cggaagccaa ggggaatgaa gtgaggccag tggccgggtc tgctgagtcc      540

gcagcactca gactacgtgc acctctgcag caggtgcagg cccagttgtc acccctccag      600

aacatctccc catggattct ggcggtattg actcttcaga ttcagagtct gatatcctgt      660

tgggcattct ggacaacttg gacccagtca tgttcttcaa atgcccttcc ccagagcctg      720

ccagcctgga ggagctccca gaggtctacc cagaaggacc cagttcctta ccagcctccc      780

tttctctgtc agtggggacg tcatcagcca agctggaagc cattaatgaa ctaattcgtt      840

ttgaccacat atataccaag cccctagtct tagagatacc ctctgagaca gagagccaag      900

ctaatgtggt agtgaaaatc gaggaagcac ctctcagccc ctcagagaat gatcaccctg      960

aattcattgt ctcagtgaag gaagaacctg tagaagatga cctcgttccg gagctgggta     1020

tctcaaatct gctttcatcc agccactgcc caaagccatc ttcctgccta ctggatgctt     1080

acagtgactg tggatacggg ggttcccttt ccccattcag tgacatgtcc tctctgcttg     1140

gtgtaaacca ttcttgggag gacacttttg ccaatgaact ctttccccag ctgattagtg     1200

tctaaggaat gatccaatac tgttgccctt ttccttgact attacactgc ctggaggata     1260

gcagagaagc ctgtctgtac ttcattcaaa aagccaaaat agagagtata cagtcctaga     1320

gaattcctct atttgttcag atctcataga tgacccccag gtattgtctt ttgacatcca     1380

gcagtccaag gtattgagac atattactgg aagtaagaaa tattactata attgagaact     1440

acagctttta agattgtact tttatcttaa aagggtggta gttttcccta aaatacttat     1500

tatgtaaggg tcattagaca aatgtcttga agtagacatg gaatttatga atggttcttt     1560

atcatttctc ttcccccttt ttggcatcct ggcttgcctc cagttttagg tcctttagtt     1620

tgcttctgta agcaacggga acacctgctg agggggctct ttccctcatg tatacttcaa     1680

gtaagatcaa gaatcttttg tgaaattata gaaatttact atgtaaatgc ttgatggaat     1740

tttttcctgc tagtgtagct tctgaaaggt gctttctcca tttatttaaa actacccatg     1800

caattaaaag gtacaatgca                                                 1820


<210>  1232
<211>  4559
<212>  DNA
<213>  homo sapiens

<400>  1232
ggttggaatt ttggcgggtt cagctgtgaa cgaagaaggc gtcccggcat cggccaagat       60

tctacattgc tcatctgggc atctgagcct ccttcgaagt ttcctgtcac aactgtcctc      120

ttgacagcat ggatgaggag gaagacaatc tgtctctgct gaccgcactg ctggaagaaa      180

atgagtcagc cttggattgt aattcagaag aaaataactt cttgacgcgg gaaaatggcg      240

agcccgacgc atttgatgag ctctttgatg ccgacggcga cggtgaatct tatacagaag      300

aggctgatga tggagaaaca ggagagacaa gagacgaaaa ggaaaatctg gccactctct      360

ttggagatat ggaggactta acagatgaag aagaagttcc cgcatcacag tcaactgaaa      420

atagggtcct ccctgctcct gcccccaggc gagagaaaac gaatgaagag ttgcaagagg      480

aattaaggaa tttgcaagag caaatgaagg ccttacaaga gcagctaaaa gtaacaacaa      540

ttaaacagac agcaagccca gcccgtctgc aaaaatcccc tgagaagtct ccccggccac      600

ctcttaagga gaggagagtt cagagaattc aggagtcaac atgcttttct gcggagcttg      660

atgtccctgc gctaccaaga accaagaggg tggctcgaac accaaaggct tcacctccag      720

atcccaaaag ctcatcttca aggatgacaa gtgcaccctc ccaaccccta cagacgattt      780

ctcggaacaa acctagtggg ataactagag gtcaaattgt ggggacccca ggaagttctg      840

gggaaacgac tcaacccatc tgtgtggaag ccttctctgg tctgcggctc aggcggcctc      900

gagtatcctc cacagaaatg aacaagaaaa tgaccggccg aaaactgatc agactgtctc      960

agatcaagga aaagatggcc agagagaagc tggaagaaat agattgggtg acatttgggg     1020

ttatattgaa gaaggttacg ccacagagtg tgaatagtgg aaaaaccttc agcatatgga     1080

aactgaatga tcttcgtgac ctgacacaat gtgtgtcctt gttcttattt ggagaagttc     1140

acaaagcgct ctggaagacg gagcagggga ctgtcgtagg gatcctcaat gccaacccca     1200

tgaagcccaa ggatggttca gaggaggtgt gtttatctat cgatcatcct cagaaggtct     1260

taattatggg tgaagctctt gacctgggaa cctgtaaagc caagaagaag aatggagagc     1320

cgtgcacgca gactgtgaat ttgcgtgact gtgagtactg tcagtaccat gtccaggctc     1380

agtacaagaa gctcagcgca aagcgtgcgg atctgcagtc caccttctct ggaggacgaa     1440

ttccaaagaa gtttgcccgc agaggcacca gcctcaaaga acggctgtgc caagatggct     1500

tttactacgg aggggtttct tctgcctcgt atgcagcttc aattgcagca gctgtggctc     1560

ctaagaagaa gattcaaacc actctgagta atctggttgt taagggcaca aacttgatca     1620

tccaggaaac acggcaaaaa ctcggaatac cccagaagag cctgtcttgc tctgaggagt     1680

tcaaggaact gatggacctg ccgacgtgtg gagccaggaa cttaaaacaa catttagcca     1740

aagccacagc ttcagggatt atggggagcc caaaaccagc catcaagtcc atctcggcct     1800

cagcactctt gaagcaacag aagcagcgga tgttggagat gaggagaagg aaatcagaag     1860

aaatacagaa gcgatttctg cagagctcaa gtgaagttga gagcccagct gtgccatctt     1920

catcaagaca gccccctgct cagcctccac ggacaggatc cgagttcccc aggctggagg     1980

gagccccggc cacaatgacg cccaagctgg ggcgaggtgt cttggaagga gatgatgttc     2040

tcttttatga tgagtcacca ccaccaagac caaaactgag tgctttagca gaagccaaaa     2100

agttagctgc tatcaccaaa ttaagggcaa aaggccaggt tcttacaaaa acaaacccaa     2160

acagcattaa gaagaaacaa aaggaccctc aggacatcct ggaggtgaag gaacgtgtag     2220

aaaaaaacac catgttttct tctcaagctg aggatgaatt ggagcctgcc aggaaaaaaa     2280

ggagagaaca acttgcctat ctggaatctg aggaatttca gaaaatccta aaagcaaaat     2340

caaaacacac aggcatcctg aaagaggccg aggctgagat gcaggagcgc tactttgagc     2400

cactggtgaa aaaagaacaa atggaagaaa agatgagaaa catcagagaa gtgaagtgcc     2460

gtgtcgtgac atgcaagacg tgcgcctata cccacttcaa gctgctggag acctgcgtca     2520

gtgagcagca tgaataccac tggcatgatg gtgtgaagag gtttttcaaa tgtccctgtg     2580

gaaacagaag catctccttg gacagactcc cgaacaagca ctgcagtaac tgtggcctct     2640

acaaatggga acgggacgga atgctaaagg aaaagactgg tccaaagata ggaggagaaa     2700

ctctgttacc aagaggagaa gaacatgcta aatttctgaa cagccttaaa taacccgaac     2760

ttcagacatt ttcccacaga cttcctggcc tcctgtgact ctggaaagca aaggattggc     2820

tgtgtattgt ccattgattc ctgattgacg ccgtcaaaaa caaatgcttg ttaagcccat     2880

aagctttgcc tgcttacttt ctgccattgg gttggtttga taccacattt aacattgaca     2940

tttaagtgga aaaccaagtt atcattgtct tttctaagct cagtgtggat gattgcatta     3000

cttcattcac tgaagttttt gcccaaaaat tggaaggtaa acagagagct atgtttctgt     3060

atcttttggt tatagagtgt tcacttcttt atcataacaa aattctagtg tttatacgaa     3120

cacccagagg caaaagaatt tggcttaatt ctcactccag gtaagtagct taacttctgg     3180

gcttcagttt tctcatctgt aaaatcagga agattggact aagtgatcct gaaatgtatt     3240

ttttagcact ggatttctac aaataataaa actttcccat ctagataatg atgatcacat     3300

agtcttgatg tacggacatt aaaagccaga tttcttcatt caattctgtt atctctgttt     3360

tactctttga aattgatcaa gccactgaat cactttgcat ttcagtttat atatatagag     3420

agaaagaagg tgtctgctct tacattattg tggagccctg tgatagaaat atgtaaaatc     3480

tcatattatt ttttttttaa tttttttatt ttttatgaca gggtctcact atgtcaccct     3540

ggctggagtg cagtagtgcg atcgcggcac actgcagcct tggcttccct gggctcaagc     3600

agtcctccca cctcagtctc ccaaatagct aggactacag gcgtgcgtga ccaagcccag     3660

ctaatttttg cattttttgt agagatgggg ttttgccatg ttgctcaggc tggtctcaaa     3720

ctcctgagca ctagcaatcc acccacctct gtttccaaaa aaaaaaaaaa aatgaaaggt     3780

caacccctat gcaaattacc acagcaaagg tttcattcag gagattcttc catctgggca     3840

acctggtttt ccaaatatca tttgacctaa gtgaatgttg atactagcta aagattgggt     3900

aaattggttg aattattgta ttgaagcttg agctgtagct aaaagtaatt taggtttccc     3960

ctaagatgtt attatgttag ggacataaca cttttgggag gttgttgtgg gagatggttg     4020

atttaggttt tcaaaagcta gaaataaaat ttacatgcct tagatttcat aaaattctgc     4080

tctaattggg tggaaggtgc tgtatctaac ttgtgttcct cctaaggtta tgtcctaata     4140

actattcttt taggagtata cttctacttt atagaaggtt gcttttcttt ttaatttttt     4200

ctaacaaaga aaagaataaa gtatttatta ataagaacca gaaagcactt gaaactgatg     4260

tttttaatgg ctcatttagg gtagatttat ttatctcatt aacttaaaac agctatgtgt     4320

atgaaatagg tcacaacaga acttgaacac caggttggtg tctgagcaat ccctttctta     4380

tgggaaaaac aatgttcttg tttgaacaga gggtatcatt gcagtcagta ttcacgtgta     4440

tattgttata taagttgtat aatatgcttg taaaggctga gggtgagctg tatctggatg     4500

cctttttaca atttgatttt aacttttaaa ataaatttaa aacataaaaa aaaaaaaaa      4559


<210>  1233
<211>  2000
<212>  DNA
<213>  homo sapiens

<400>  1233
acgccggcgc tcccaggccg cgcttcctgc gtccccaacc cggtccctga gagggcagtg       60

cgccctctcc accactgcgt tccctcggct aagaatcccc cgaaccccag ccccgcgatc      120

gcggcgccca ccgaggaggc cgcccgggtg gggcgcgggg gtcgcgaagc ccgcagtccc      180

ggaccgccca gccgagacgg agccggaccc gccgcctccc gggtggatct ttaactcaag      240

actagcatga agagttgcct tctggcctgc cctgagtctc ctcaaataac aacaggccct      300

tccaccgcag ccatccgcac gggaggcctc gcgattgctc ggaaccatcc cgcaggagtt      360

cagctgatat tttctagtgt ggggcgagag attttgtgga gcgcatttaa ggggtttttg      420

ttgtgactgc tgccttgtat atatttattt tctttcttgg aactgggcct cgccctcctc      480

ccactgacat gatggcccag tccaaggcca atggctcgca ctatgcgctg accgccatcg      540

gcctggggat gctggtcctt ggggtgatca tggccatgtg gaacctggta cccggcttca      600

gcgcggccga gaagccaaca gctcagggca gcaacaagac cgaggtgggt ggcggcatcc      660

tcaagagcaa gaccttctct gtggcctacg tgctggtcgg ggccggggtg atgctgctgc      720

tgctttctat ctgcctgagt atcagggata agaggaagca gcggcagggc gaggacctgg      780

cccatgtcca gcacccgaca ggcgctgggc ctcacgccca ggaggaagac agccaggagg      840

aagaagagga ggatgaggag gctgcctcaa ggtactatgt tcccagctac gaggaagtga      900

tgaacacaaa ctactcagaa gcaaggggag aggagcagaa cccgaggttg agcatctctc      960

tcccgtccta tgagtcactg acggggctcg acgagaccac ccccacatcc accagggctg     1020

acgtggaggc cagccctggg aacccccctg acaggcagaa ctctaagttg gccaaacgac     1080

tgaaaccgct gaaagttcga aggattaaat ctgaaaagct tcacctcaaa gactttagga     1140

tcaacctccc agacaaaaac gtccctcctc cctcgataga gcctttgact cctccaccgc     1200

agtatgatga agtccaggag aaggcccccg acacccggcc gcccgactga atggccccac     1260

ttgagccacg ctccctcctg tctctcacac ctttcacccc caagactcta acaaagccac     1320

atgagccaca gttgagaagc ggaggggcca gctgtgcatg gagccatttg gatggcggcg     1380

ggcggggggg gattctctgt atcaggagtg actttgttgc cccacacagc ctcctgctgc     1440

aggtgctttg gaaagagatg ctgccttgga gctggtgaat ctgtggacca cattcaaggg     1500

tgtggcacag gcatcttccc atccttttca ctccgaatcg ctggcgacac attctccttt     1560

ccagctagga aagggttcct cgcggctggt ttagattgtg gttgtttgtt ttgcttctac     1620

taagactgtt ttgtttcaaa aaggaaacaa gttttgtgtt tgctgtctac gctggagtcc     1680

tgaactgtgg gtagaaaaca cgacctggct ttgtagaaag gacacagggc tgttttatga     1740

actaagcggt gaggctcagg tggcggctct cgcagagccc ctgatgctgt tgttctttga     1800

gggcttaagg cctgatgaac gtaggcacgt gatgcataat agtcttcaat ggtacactta     1860

actagtctct tctgtgtaac agcaaaaaaa aaaaaaaaaa gaagaagaaa gaaaactgta     1920

ggaaatgttc tttttgaaat gccatgcaat ggagcttttt gtaataaaat attttatatg     1980

tagtaaaaaa aaaaaaaaaa                                                 2000


<210>  1234
<211>  10022
<212>  DNA
<213>  homo sapiens

<400>  1234
aattgctccg ggagagacac aggactggag ggcttgagga atgtggtggt ccctctcttc       60

gttgtttctg ccccctgagg ttgtgctttc tcagggatat gcactctgca cttccattcc      120

tgcagtgaaa ttaactcgag cttggcagct cgagaggaga atgtggccac tttccgaggc      180

tcagagtatc tgtgctacga cctgtctcag aacccgatcc agagcagcag tgatgaaatc      240

accctctcct ttaagacctg gcagcgtaac ggcctcatcc tgcacacggg caagtcggct      300

gactatgtca acctggctct gaaggatggt gcggtctcct tggtcattaa cctggggtcc      360

ggggcctttg aggccattgt ggagccagtg aatggaaaat tcaacgacaa cgcctggcat      420

gatgtcaaag tgacacgcaa cctccggcag gtgacaatct ctgtggatgg cattcttacc      480

acgacgggct acactcaaga ggactatacc atgctgggct cggacgactt cttctatgta      540

ggaggaagcc caagtaccgc tgacttgcct ggctcccctg tcagcaacaa cttcatgggc      600

tgccttaaag aggttgttta taagaataat gacatccgtc tggagctgtc tcgcctggcc      660

cggattgcgg acaccaagat gaaaatctat ggcgaagttg tgtttaagtg tgagaatgtg      720

gccacactgg accccatcaa ctttgagacc ccagaggctt acatcagctt gcccaagtgg      780

aacactaaac gtatgggctc catctccttt gacttccgca ccacagagcc caatggcctg      840

atcctcttca ctcatggaaa gccccaagag aggaaggatg ctcggagcca gaagaataca      900

aaagtagact tctttgccgt ggaactcctc gatggcaacc tgtacttgct gcttgacatg      960

ggctctggca ccatcaaagt gaaagccact cagaagaaag ccaatgatgg ggaatggtac     1020

catgtggaca ttcagcgaga tggcagatca ggtactatat cagtgaacag caggcgcacg     1080

ccattcaccg ccagtgggga gagcgagatc ctggacctgg aaggagacat gtacctggga     1140

gggctgccgg agaaccgtgc tggccttatt ctccccaccg agctgtggac tgccatgctc     1200

aactatggct acgtgggctg catccgcgac ctattcattg atgggcgcag caagaacatt     1260

cgacagctgg cagagatgca gaatgctgcg ggtgtcaagt cctcctgttc acggatgagt     1320

gccaagcagt gtgacagcta cccctgcaag aataatgctg tgtgcaagga cggctggaac     1380

cgcttcatct gcgactgcac cggcaccgga tactggggaa gaacctgcga aagggaggca     1440

tccatcctga gctatgatgg tagcatgtac atgaagatca tcatgcccat ggtcatgcat     1500

actgaggcag aggatgtgtc cttccgcttc atgtcccagc gagcttatgg gctgctggtg     1560

gctacgacct ccagggactc tgccgacacc ctgcgtctgg agctggatgg ggggcgtgtc     1620

aagctcatgg ttaacttaga ctgtatcagg ataaactgta actccagcaa aggaccagag     1680

accttgtatg cagggcagaa gctcaatgac aacgagtggc acaccgttcg ggtggtgcgg     1740

agaggaaaaa gccttaagtt aaccgtggat gatgatgtgg ctgagggtac aatggtggga     1800

gaccataccc gtttggagtt ccacaacatt gaaacgggaa tcatgactga gaaacgctac     1860

atctccgttg tcccctccag ctttattggc catctgcaga gcctcatgtt taatggcctt     1920

ctctacattg acttgtgcaa aaatggtgac attgattatt gtgagctgaa ggctcgtttt     1980

ggactgagga acatcatcgc tgaccctgtc acctttaaga ccaagagcag ctacctgagc     2040

cttgccactc ttcaggctta cacctccatg cacctcttct tccagttcaa gaccacctca     2100

ccagatggct tcattctctt caatagtggt gatggcaatg acttcattgc agtcgagctt     2160

gtcaaggggt atatacacta cgtttttgac ctcggaaacg gtcccaatgt gatcaaaggc     2220

aacagtgacc gccccctgaa tgacaaccag tggcacaatg tcgtcatcac tcgggacaat     2280

agtaacactc atagcctgaa agtggacacc aaagtggtca ctcaggttat caatggtgcc     2340

aaaaatctgg atttgaaagg tgatctctat atggctggtc tggcccaagg catgtacagc     2400

aacctcccaa agctcgtggc ctctcgagat ggctttcagg gctgtctagc atcagtggac     2460

ttgaatggac gcctgccaga cctcatcaat gatgctcttc atcggagcgg acagatcgag     2520

cgtggctgtg aaggacccag taccacctgc caggaagatt catgtgccaa ccagggggtc     2580

tgcatgcaac aatgggaggg cttcacctgt gattgttcta tgacctctta ttctggaaac     2640

cagtgcaatg atcctggcgc tacgtacatc tttgggaaaa gtggtgggct tatcctctac     2700

acctggccag ccaatgacag gcccagcacg cggtctgacc gccttgccgt gggcttcagc     2760

accactgtga aggatggcat cttggtccgc atcgacagtg ctccaggact tggtgacttc     2820

ctccagcttc acatagaaca ggggaaaatt ggagttgtct tcaacattgg cacagttgac     2880

atctccatca aagaggagag aacccctgta aatgacggca aataccatgt ggtacgcttc     2940

accaggaacg gcggcaacgc caccctgcag gtggacaact ggccagtgaa tgaacattat     3000

cctacaggcc ggcagttaac catcttcaac actcaggcgc aaatagccat tggtggaaag     3060

gacaaaggac gcctcttcca aggccaactc tctgggctct attatgatgg tttgaaagta     3120

ctgaacatgg cggctgagaa caaccccaat attaaaatca atggaagtgt tcggctggtt     3180

ggagaagtcc catcaatttt gggaacaaca cagacgacct ccatgccacc agaaatgtct     3240

actactgtca tggaaaccac tactacaatg gcgactacca caacccgtaa gaatcgctct     3300

acagccagca ttcagccaac atcagatgat cttgtttcat ctgctgaatg ttcaagtgat     3360

gatgaagact ttgttgaatg tgagccgagt acagcaaacc ccacggagcc gggaatcaga     3420

cgggttccgg gggcctcaga ggtgatccgg gagtcgagca gcacaacagg gatggtcgtc     3480

ggcattgtgg ctgctgccgc cctctgcatc ttgatcctcc tgtacgccat gtacaagtac     3540

aggaacaggg acgaggggtc ctatcaagtg gacgagacgc ggaactacat cagcaactcc     3600

gcccagagca acggcacgct catgaaggag aagcagcaga gctcgaagag cggccacaag     3660

aaacagaaaa acaaggacag ggagtattac gtgtaaacat gcgaacactg ctcacacgcg     3720

agttttcaca gttatttcta tccacgccta tgaatctttg gacggtgaga tctcacagat     3780

gtcagaactg ctggaactat gaaatggggt atataaccac gactctggtg gggaaaaccg     3840

ttttttaaag gacacacaca cacacagcga tgcatctctc tctaaagctc agccacggct     3900

gcggcaaggt cccagcggtc gctgggagac agaaggtttt gtgccctgct gtatcataaa     3960

gcacacactt agcgctctgg agccggacgg tggctccacc acttccgcag gcctggaaac     4020

ttccttctcc ggaggacctt ttactaaaag gtagaagact tcatggctta cttgttccat     4080

aactccaagt gagtctgtaa tgtttgtgaa gcttgactgt aaccatgttt tttctgttta     4140

attatgtaaa aaacaaaact acaacaacaa aaaaagaaaa aagttaaaaa agaaaaaaac     4200

accaaaaaac aaaaacaaac aaaaaaaaaa acccacaacc cttatctggt tctgaccagt     4260

gtgcgtgtaa ctttatgatc tgaggggaaa aatggctttt gggtttttgt ttattttttt     4320

gataatgact ggacatcaga agaggaaaaa aactcaaaac aaaagcgaga gagactattg     4380

ccatatgaac tcaaaagcta tcatggtgtt cactctacat atcaggttat ggtgtctcta     4440

gaatctgttg tttgtttcct ataagatgct ttgctgaaca catagcaaaa ttcatgtgac     4500

ggatgataaa ttgattcgaa aagctggtcc cccaggatct aatttcagaa tttaccaccc     4560

aaacccggaa cagatgggtt tagggctggt gttatcagag ctattggctt tacgtaacaa     4620

tattgttcct gtccattcac ccagccaaat tgtgttaaag aggaaagccc cacaaactaa     4680

aacagccttt cctagggaag aggaagggga ggtgggctgg atctgtgact gattgaaatg     4740

catgcaaata aaaaagacaa tattaaagtc tgttatcaaa ccagacagta ggggagttca     4800

actcgtgatg gaaccacaaa aggtcacaca agccaaccat gtcatgccag agtacaaaac     4860

acatagttct ttccccgccc cgaatgtgac aatggttttc atagtggttt aattttgtag     4920

cctgacattt atggataact ctgtccttcc atttgctcac ttctctcttc acccatcttt     4980

tttaaaaaca aataaatgaa taaagctgct gtgacacaca cacaaaagga atttaatagt     5040

ataatatata tataaataaa tatatataca gatatattta tcatggtatg tttgatggga     5100

tgactgacac aggaaatctg ttaaagtctt aaaatggaat gagaatgttg ttttaaaaga     5160

aaatagcaaa acaacaaaaa agcaaacctt aaaatgtgaa gaaagtgtga attttagttt     5220

tgtcacagtt aactgtgtca aagagaatta aaaaaaaaaa cttcagattt tgtttacata     5280

ttttactaca tttttgctgg tataattcct tagccaccta tgtacatact gctttaagaa     5340

atgttttttt cctgtttatt tctgtttggt ttatattctg gttgtctttt tctttttgta     5400

aagaggaaac aatgtacaga aaaacaataa actggttgta tggccatagc tatccgaaaa     5460

gcaagagaca aagcaagaca aatattcaca caaaaatgaa gtgtgtcctc tggagggtca     5520

gatatacaat ttcttttgta cagatgaaaa tcaatcagct gcttagattt agaaatctac     5580

tcttgctggt ctttgtaagt tgcatgaata tttgactttg aaaaaatatc ttaacgacat     5640

ggggcaaaaa gtgcaatcta aatggtagcc tttactaatg tgtgtggaaa gaggtgttcc     5700

tcattatcta atatttcaat gtgttaagag tttaattttt ttgttatcat taaaaaagac     5760

aggattataa agagatatca aagcacgatt ttagataacc taaacggccc agcctatacg     5820

aagttgatta tatctcgatg tctgtaaaag attgctgttc ttggagtctt gaggtcttgt     5880

gaattgattt cctgctttct ttcatttttt tcaatttaag taataataca tttgttatat     5940

tcctttcagt gtaagtttct atttggacaa ttttatggga acatgtgcat tctctatgtg     6000

agcttctatc atattcctgt tttattagca gaacctaaag gaatttattt aatgatgttg     6060

tgacattact gctttttctt ttttcttttc ttagttcata tttgcatttt cgttcaagga     6120

tatgcttagc aataaaatgt tcttcccaaa accttgtatg ctgatgcact tttattttct     6180

taacatttga gaaaatctcg cactgaagct aattatgtca tatcttatta aaagccgagt     6240

aagagctaga ccactttcat gtgatagaag atattctaag cagttactaa ttattacatt     6300

atcaaaatgc catatttatg agataattat ctgttacttg aggcattatt ttttagattg     6360

ctatgataga ataaccagga gggagtgcat ttttctggaa agatgataga aacattgtat     6420

tctagaaaag attattggat actatggttt tgtttgtttg tttttgtttt ttgtttttcg     6480

ttttttgttt gttttttttt tgagacagag tctcgctctg tcgcccgggc tggagtgcag     6540

tggcacgatc tcggctcact gcaagctccg cctcccgggt tcacaccatt ctcctgcctc     6600

agccccccga gtaggtggga ctacaggtgc ccgccaccac gcccggctaa ttttttgtat     6660

ttttcgtaga gacggggttt caccgtgtta gccgggatgg tctcgatctc ctgacctcgt     6720

aatccacccg cctcggcctc ccaaagtgct gggattacag gcgtgagcca ccgcgcccgg     6780

cttggatact atgtttttta aaggcatttc gtacctttta cgtattttct ataagtcaac     6840

aagctttaaa cagtatttaa aactatgttc acatagtgcc ataagcacta gaaagtctta     6900

gatgtcttct ttccaagcct cccaccatat taaaatttaa aattaaaaaa cagaatccaa     6960

aaccaaaatt taaatgagtt cttcaatttt aacagcttct tacaagaatt tctgattaca     7020

acttgtttca tacacccatt gtagcagtaa tgtctcatat ttctcgttct ctcagcacac     7080

acttacttgg ccaattggat aatccatcta ccctttgttc ttcactgtaa tctagaaata     7140

tagatttaac tgaacagctg tcctttatcc atatgttggt taccagtttt caaagagtta     7200

gaattttaaa aatatatatt tagttaagcc tgtgccttca agataacatt agtggagtgg     7260

ttatactatc gactatgtta ggaatggggg ggagaaagtc aggttcagtg atgtcaaatt     7320

atgtaaagtt ttttttttgt tcctgtcttc aaagttctgt attagatgtt ctcccatcat     7380

tttttgagat ggagtcttgc agcctacagt gcagtggcat gatattggct cactgcaacc     7440

tctgcctctc aacctcaaac gattctcctg cctcagcctc ctgagtagct gcgactacag     7500

gcatgggcca ccacacccag ctcatttttt aatttatttt ttattttttt agtaaggaag     7560

ggtttcacca tgttggcaag gctggtctcg aactccttac ttcaagtgat ccacccacct     7620

tggccttgca aaatgctggg attataggtg tgagccactc ctcctgaaat ctttctaaat     7680

ctcactaata tataattcta ggactacttt aagcattcac tttttcttta attcaagaaa     7740

catttattga acacttatgt acaagctagt ctactattgg ctattgttac tttgtttcaa     7800

tgaaggcaga aaatggctag aaggatttta agcctttttg tctcttgtat aaatctatac     7860

aggtccagtc tctctttgct catattcaaa ttgaagtttg atctttctcc aaaaaatatc     7920

caagccctgt gtttgtccca gttgaactaa tatcttgatt atatagttta agatcagttt     7980

gataatgtct attgaatatt tactaaatga ttatgggata ttaaattgag agccttggga     8040

gcttatcatc tagtaaagat gaacaaaaaa tggtactata gtgaatgcaa ataagctatc     8100

aaaaagtaca aactaagttg ggagcttaga agaaattatg taagggaagg cttcatagaa     8160

ggggtgacat tttggtaaac cttggaaaac tgataggcag aaataagggc tgtatatcat     8220

tctaagcaaa cccttaaagt gggagcaagc aggatcaaaa ccataatttg gattgatgac     8280

agactgcaaa aagtacattg gaggaagata tgagtaggaa ggtttttgaa atcatgtcaa     8340

tgaatgggaa gagagaaatg ggagaatagc ttgagaagtt caaggtcaag ggctgctttg     8400

tcgagtacaa aggactcgag catatttgaa atgaaaggta ataactgatc tactcttatg     8460

gagcaaccga gtttcctgat agagatgttt atctggggga aaaaggcata agtcaatctt     8520

cttggagaga atgggatcag aaactgacat attgctacag aggttacaaa agctgtagtc     8580

agagggcttc agtgttctgg atatattaaa ggacaaggtc agatacccaa gtgggaccgt     8640

gagtgattaa tggcagcagt ccactgacag caccagtagg aaggcgctaa tgaaaagatc     8700

tctaaatatc agtaaggggt tagctgccat taataataca actttatagc tttactattt     8760

tttcttttat tgttgaaata gtgagggcac gtatttttct aattgtgttt attacaaaga     8820

aaacagaccc gaagaactta aatgacttct ccaaggtcac acagctaata catgacaatg     8880

tcatgactta aaatccagtc ttgtggttcc aaatttagag ctctttcata aacctgtctc     8940

tagagaagca agtcattttc tactttttcc agaagcattt gaagtggaag ctaaggcagg     9000

aaatgagagg atattgtgtt agtctactgg gattaccctg gcaaaatacc acaggctggg     9060

tagacaactg aaatgtattt ctcagttcca gaaacaaagt tgcagatcaa agtttgttag     9120

ggctcagttt ctgggaaggg ctctcttcct ggcttgtaga taataagcta ccttctcact     9180

atgtactcac agggcctttc ttctgttcat gcactgagag atttcttttt cttgctcttc     9240

ttataagacc accagtgcta ttggttaaag ccctgccatt atgactttgt ttgaccttaa     9300

ttacttccta aagacactac ctcccaatac agtcatgttt ggggttggga cttcaacata     9360

tgaatgttgg aggggatatg gttctgtttc tagcaaatgt atagtagtgg gaattgcaaa     9420

ggttgaagtt ccaaagtatc aagggaatca gaattgggaa gcaattctaa cctttttgaa     9480

gtggttacat ggcccaagta gaagagcaaa taattccaag agacaccaag ccacagagca     9540

ggtaggatca cgtgagtagg gcccaggata gaagagcagt gttagggttg catgagagtg     9600

agggcatata agacaacaac agctaaaagc aatgcatgct cagatcttgg gagatgtatt     9660

aaatgagtag agtgaatttc aagatatctg agtttttttt ttttaatgat tacatgggtt     9720

ctagagtcaa aatgccatgg ctcatctggt actgtaactt aagataaact gcttagctaa     9780

ggctcagctt tcatacctat aattttgtta tacttatctt gcaggtttct tgagaaatat     9840

tggatgaaat aattcatgtg aaatgcttaa catatgtgtg acaaataatt atccttaaat     9900

aaatgttggt cgttattaca attggctttg ttacttgatt caggcaggat caaaattagc     9960

tgctatatgc atgactaacc aggaccaaaa agttaataaa aatacgaaag tttggcactc    10020

tt                                                                   10022


<210>  1235
<211>  8578
<212>  DNA
<213>  homo sapiens

<400>  1235
atatgacttg cccatttgtg aatttggctc cccaactcct cgcttcactt cacctgtgcc       60

tccctggtcc gcgcacttcg caggcgcccg cccgcctctc ggccacctct gcagcctgcc      120

aggcacctcc tcttgcgctc tcgctgattt cgcccaccca cctccctcca ccccgtgcca      180

cgttggtttg ggtggctgct ccgcaccggg ttcctcctcc tctcctcttt ccctccagtc      240

cttcttattc tcttcctctg gctgcggtgg ctgctgctgc tgctggtttt catccagttg      300

ggaaacccag gaagccggcg gctgctccgt ggcgctagtc cagcacgccc agggttaaaa      360

gcctcgcgcc cttccgcgga gactcccagg aacacccgaa gaactcttcc acctgcagcc      420

cccttttgcc tggcagttct gcattgcatc tcatggaagt ggaaacagga aaataaaaat      480

gttcaaactc cttggatgtt gggataaact cacctgaacc cacttgggtt cgggctgcct      540

ccttctcttc cttcattgcc acctttcctc tgtgtggctc ccgggagtgt gcggttaagt      600

catcagactc gaagtgccta gagatccgga ggaagccgcg ccggtcttcc cctgacatgc      660

gtggcatgcc ggggctccgt aggaggtttg ctatacctgg gaggaccctg gcattctaaa      720

tttcagctcc gggaaagaga aggggctttt tgccttttat cttttttttt tctttcttta      780

agtagtaatt ttttaactga ttcattgttt ggaaagcgca tattgcttcc ctcttccccg      840

aattctggca actcttcctc ctgctatgat gggcccttgg gcatcatgaa cttcattact      900

cctcactggc tggaattcaa actgcccatc tgtagtggtc ccgtgcgttg accatgcacc      960

tgagaatcca cgcgagacgg agccctcctc gccggccggc ctggacgctt gggatctggt     1020

tcctgttctg gggatgtatc gtcagctctg tatggagttc ttctaatgta gcttcctcct     1080

cctccacctc ttcctcgccg gggtctcact ctcagcacga gcaccatttc catggcagca     1140

agcatcactc agtgcctatt tctatctatc gttcccctgt ttcccttcga ggaggacacg     1200

ctggcgctac gtacatcttt gggaaaagtg gtgggcttat cctctacacc tggccagcca     1260

atgacaggcc cagcacgcgg tctgaccgcc ttgccgtggg cttcagcacc actgtgaagg     1320

atggcatctt ggtccgcatc gacagtgctc caggacttgg tgacttcctc cagcttcaca     1380

tagaacaggg gaaaattgga gttgtcttca acattggcac agttgacatc tccatcaaag     1440

aggagagaac ccctgtaaat gacggcaaat accatgtggt acgcttcacc aggaacggcg     1500

gcaacgccac cctgcaggtg gacaactggc cagtgaatga acattatcct acaggccggc     1560

agttaaccat cttcaacact caggcgcaaa tagccattgg tggaaaggac aaaggacgcc     1620

tcttccaagg ccaactctct gggctctatt atgatggttt gaaagtactg aacatggcgg     1680

ctgagaacaa ccccaatatt aaaatcaatg gaagtgttcg gctggttgga gaagtcccat     1740

caattttggg aacaacacag acgacctcca tgccaccaga aatgtctact actgtcatgg     1800

aaaccactac tacaatggcg actaccacaa cccgtaagaa tcgctctaca gccagcattc     1860

agccaacatc agatgatctt gtttcatctg ctgaatgttc aagtgatgat gaagactttg     1920

ttgaatgtga gccgagtaca ggtaggtcag caaaccccac ggagccggga atcagacggg     1980

ttccgggggc ctcagaggtg atccgggagt cgagcagcac aacagggatg gtcgtcggca     2040

ttgtggctgc tgccgccctc tgcatcttga tcctcctgta cgccatgtac aagtacagga     2100

acagggacga ggggtcctat caagtggacg agacgcggaa ctacatcagc aactccgccc     2160

agagcaacgg cacgctcatg aaggagaagc agcagagctc gaagagcggc cacaagaaac     2220

agaaaaacaa ggacagggag tattacgtgt aaacatgcga acactgctca cacgcgagtt     2280

ttcacagtta tttctatcca cgcctatgaa tctttggacg gtgagatctc acagatgtca     2340

gaactgctgg aactatgaaa tggggtatat aaccacgact ctggtgggga aaaccgtttt     2400

ttaaaggaca cacacacaca cagcgatgca tctctctcta aagctcagcc acggctgcgg     2460

caaggtccca gcggtcgctg ggagacagaa ggttttgtgc cctgctgtat cataaagcac     2520

acacttagcg ctctggagcc ggacggtggc tccaccactt ccgcaggcct ggaaacttcc     2580

ttctccggag gaccttttac taaaaggtag aagacttcat ggcttacttg ttccataact     2640

ccaagtgagt ctgtaatgtt tgtgaagctt gactgtaacc atgttttttc tgtttaatta     2700

tgtaaaaaac aaaactacaa caacaaaaaa agaaaaaagt taaaaaagaa aaaaacacca     2760

aaaaacaaaa acaaacaaaa aaaaaaaccc acaaccctta tctggttctg accagtgtgc     2820

gtgtaacttt atgatctgag gggaaaaatg gcttttgggt ttttgtttat ttttttgata     2880

atgactggac atcagaagag gaaaaaaact caaaacaaaa gcgagagaga ctattgccat     2940

atgaactcaa aagctatcat ggtgttcact ctacatatca ggttatggtg tctctagaat     3000

ctgttgtttg tttcctataa gatgctttgc tgaacacata gcaaaattca tgtgacggat     3060

gataaattga ttcgaaaagc tggtccccca ggatctaatt tcagaattta ccacccaaac     3120

ccggaacaga tgggtttagg gctggtgtta tcagagctat tggctttacg taacaatatt     3180

gttcctgtcc attcacccag ccaaattgtg ttaaagagga aagccccaca aactaaaaca     3240

gcctttccta gggaagagga aggggaggtg ggctggatct gtgactgatt gaaatgcatg     3300

caaataaaaa agacaatatt aaagtctgtt atcaaaccag acagtagggg agttcaactc     3360

gtgatggaac cacaaaaggt cacacaagcc aaccatgtca tgccagagta caaaacacat     3420

agttctttcc ccgccccgaa tgtgacaatg gttttcatag tggtttaatt ttgtagcctg     3480

acatttatgg ataactctgt ccttccattt gctcacttct ctcttcaccc atctttttta     3540

aaaacaaata aatgaataaa gctgctgtga cacacacaca aaaggaattt aatagtataa     3600

tatatatata aataaatata tatacagata tatttatcat ggtatgtttg atgggatgac     3660

tgacacagga aatctgttaa agtcttaaaa tggaatgaga atgttgtttt aaaagaaaat     3720

agcaaaacaa caaaaaagca aaccttaaaa tgtgaagaaa gtgtgaattt tagttttgtc     3780

acagttaact gtgtcaaaga gaattaaaaa aaaaaacttc agattttgtt tacatatttt     3840

actacatttt tgctggtata attccttagc cacctatgta catactgctt taagaaatgt     3900

ttttttcctg tttatttctg tttggtttat attctggttg tctttttctt tttgtaaaga     3960

ggaaacaatg tacagaaaaa caataaactg gttgtatggc catagctatc cgaaaagcaa     4020

gagacaaagc aagacaaata ttcacacaaa aatgaagtgt gtcctctgga gggtcagata     4080

tacaatttct tttgtacaga tgaaaatcaa tcagctgctt agatttagaa atctactctt     4140

gctggtcttt gtaagttgca tgaatatttg actttgaaaa aatatcttaa cgacatgggg     4200

caaaaagtgc aatctaaatg gtagccttta ctaatgtgtg tggaaagagg tgttcctcat     4260

tatctaatat ttcaatgtgt taagagttta atttttttgt tatcattaaa aaagacagga     4320

ttataaagag atatcaaagc acgattttag ataacctaaa cggcccagcc tatacgaagt     4380

tgattatatc tcgatgtctg taaaagattg ctgttcttgg agtcttgagg tcttgtgaat     4440

tgatttcctg ctttctttca tttttttcaa tttaagtaat aatacatttg ttatattcct     4500

ttcagtgtaa gtttctattt ggacaatttt atgggaacat gtgcattctc tatgtgagct     4560

tctatcatat tcctgtttta ttagcagaac ctaaaggaat ttatttaatg atgttgtgac     4620

attactgctt tttctttttt cttttcttag ttcatatttg cattttcgtt caaggatatg     4680

cttagcaata aaatgttctt cccaaaacct tgtatgctga tgcactttta ttttcttaac     4740

atttgagaaa atctcgcact gaagctaatt atgtcatatc ttattaaaag ccgagtaaga     4800

gctagaccac tttcatgtga tagaagatat tctaagcagt tactaattat tacattatca     4860

aaatgccata tttatgagat aattatctgt tacttgaggc attatttttt agattgctat     4920

gatagaataa ccaggaggga gtgcattttt ctggaaagat gatagaaaca ttgtattcta     4980

gaaaagatta ttggatacta tggttttgtt tgtttgtttt tgttttttgt ttttcgtttt     5040

ttgtttgttt tttttttgag acagagtctc gctctgtcgc ccgggctgga gtgcagtggc     5100

acgatctcgg ctcactgcaa gctccgcctc ccgggttcac accattctcc tgcctcagcc     5160

ccccgagtag gtgggactac aggtgcccgc caccacgccc ggctaatttt ttgtattttt     5220

cgtagagacg gggtttcacc gtgttagccg ggatggtctc gatctcctga cctcgtaatc     5280

cacccgcctc ggcctcccaa agtgctggga ttacaggcgt gagccaccgc gcccggcttg     5340

gatactatgt tttttaaagg catttcgtac cttttacgta ttttctataa gtcaacaagc     5400

tttaaacagt atttaaaact atgttcacat agtgccataa gcactagaaa gtcttagatg     5460

tcttctttcc aagcctccca ccatattaaa atttaaaatt aaaaaacaga atccaaaacc     5520

aaaatttaaa tgagttcttc aattttaaca gcttcttaca agaatttctg attacaactt     5580

gtttcataca cccattgtag cagtaatgtc tcatatttct cgttctctca gcacacactt     5640

acttggccaa ttggataatc catctaccct ttgttcttca ctgtaatcta gaaatataga     5700

tttaactgaa cagctgtcct ttatccatat gttggttacc agttttcaaa gagttagaat     5760

tttaaaaata tatatttagt taagcctgtg ccttcaagat aacattagtg gagtggttat     5820

actatcgact atgttaggaa tgggggggag aaagtcaggt tcagtgatgt caaattatgt     5880

aaagtttttt ttttgttcct gtcttcaaag ttctgtatta gatgttctcc catcattttt     5940

tgagatggag tcttgcagcc tacagtgcag tggcatgata ttggctcact gcaacctctg     6000

cctctcaacc tcaaacgatt ctcctgcctc agcctcctga gtagctgcga ctacaggcat     6060

gggccaccac acccagctca ttttttaatt tattttttat ttttttagta aggaagggtt     6120

tcaccatgtt ggcaaggctg gtctcgaact ccttacttca agtgatccac ccaccttggc     6180

cttgcaaaat gctgggatta taggtgtgag ccactcctcc tgaaatcttt ctaaatctca     6240

ctaatatata attctaggac tactttaagc attcactttt tctttaattc aagaaacatt     6300

tattgaacac ttatgtacaa gctagtctac tattggctat tgttactttg tttcaatgaa     6360

ggcagaaaat ggctagaagg attttaagcc tttttgtctc ttgtataaat ctatacaggt     6420

ccagtctctc tttgctcata ttcaaattga agtttgatct ttctccaaaa aatatccaag     6480

ccctgtgttt gtcccagttg aactaatatc ttgattatat agtttaagat cagtttgata     6540

atgtctattg aatatttact aaatgattat gggatattaa attgagagcc ttgggagctt     6600

atcatctagt aaagatgaac aaaaaatggt actatagtga atgcaaataa gctatcaaaa     6660

agtacaaact aagttgggag cttagaagaa attatgtaag ggaaggcttc atagaagggg     6720

tgacattttg gtaaaccttg gaaaactgat aggcagaaat aagggctgta tatcattcta     6780

agcaaaccct taaagtggga gcaagcagga tcaaaaccat aatttggatt gatgacagac     6840

tgcaaaaagt acattggagg aagatatgag taggaaggtt tttgaaatca tgtcaatgaa     6900

tgggaagaga gaaatgggag aatagcttga gaagttcaag gtcaagggct gctttgtcga     6960

gtacaaagga ctcgagcata tttgaaatga aaggtaataa ctgatctact cttatggagc     7020

aaccgagttt cctgatagag atgtttatct gggggaaaaa ggcataagtc aatcttcttg     7080

gagagaatgg gatcagaaac tgacatattg ctacagaggt tacaaaagct gtagtcagag     7140

ggcttcagtg ttctggatat attaaaggac aaggtcagat acccaagtgg gaccgtgagt     7200

gattaatggc agcagtccac tgacagcacc agtaggaagg cgctaatgaa aagatctcta     7260

aatatcagta aggggttagc tgccattaat aatacaactt tatagcttta ctattttttc     7320

ttttattgtt gaaatagtga gggcacgtat ttttctaatt gtgtttatta caaagaaaac     7380

agacccgaag aacttaaatg acttctccaa ggtcacacag ctaatacatg acaatgtcat     7440

gacttaaaat ccagtcttgt ggttccaaat ttagagctct ttcataaacc tgtctctaga     7500

gaagcaagtc attttctact ttttccagaa gcatttgaag tggaagctaa ggcaggaaat     7560

gagaggatat tgtgttagtc tactgggatt accctggcaa aataccacag gctgggtaga     7620

caactgaaat gtatttctca gttccagaaa caaagttgca gatcaaagtt tgttagggct     7680

cagtttctgg gaagggctct cttcctggct tgtagataat aagctacctt ctcactatgt     7740

actcacaggg cctttcttct gttcatgcac tgagagattt ctttttcttg ctcttcttat     7800

aagaccacca gtgctattgg ttaaagccct gccattatga ctttgtttga ccttaattac     7860

ttcctaaaga cactacctcc caatacagtc atgtttgggg ttgggacttc aacatatgaa     7920

tgttggaggg gatatggttc tgtttctagc aaatgtatag tagtgggaat tgcaaaggtt     7980

gaagttccaa agtatcaagg gaatcagaat tgggaagcaa ttctaacctt tttgaagtgg     8040

ttacatggcc caagtagaag agcaaataat tccaagagac accaagccac agagcaggta     8100

ggatcacgtg agtagggccc aggatagaag agcagtgtta gggttgcatg agagtgaggg     8160

catataagac aacaacagct aaaagcaatg catgctcaga tcttgggaga tgtattaaat     8220

gagtagagtg aatttcaaga tatctgagtt tttttttttt aatgattaca tgggttctag     8280

agtcaaaatg ccatggctca tctggtactg taacttaaga taaactgctt agctaaggct     8340

cagctttcat acctataatt ttgttatact tatcttgcag gtttcttgag aaatattgga     8400

tgaaataatt catgtgaaat gcttaacata tgtgtgacaa ataattatcc ttaaataaat     8460

gttggtcgtt attacaattg gctttgttac ttgattcagg caggatcaaa attagctgct     8520

atatgcatga ctaaccagga ccaaaaagtt aataaaaata cgaaagtttg gcactctt       8578


<210>  1236
<211>  5246
<212>  DNA
<213>  homo sapiens

<400>  1236
agttccgggt gcgcggcccc ggatgttggc tgctcttgct gccgccgccg ctctcggggc       60

tgctcggggc ctcgaccgct cgcagtaggc accgttggga cctttcccgg gggggcggag      120

acgcacggag cggccggggg ctcggccggg ccgtcccggc ctgcgcagcc tgagattctc      180

tttgtggcca gatgggtttg tatggacagg cttgtccatc tgtaacttca ttaaggatga      240

catctgaact ggagagcagc ctaacgtcta tggactggtt accacagctc accatgagag      300

cagccatcca aaaatctgat gctacacaaa atgcacatgg aacaggaatt tctaagaaga      360

atgcactcct tgacccaaat acaactctgg accaggaaga agtccaacag cacaaagatg      420

ggaaacctcc atacagttat gccagcctca ttacatttgc aattaatagc tcacccaaaa      480

agaaaatgac tttaagtgaa atttatcagt ggatttgtga taacttccca tattatagag      540

aggctggcag tggttggaag aattccatac gacataatct gtcattgaac aaatgtttcc      600

ttaaagtgcc tcgatctaag gatgaccctg gaaaggggtc ctactgggca atagacacca      660

atccgaagga agatgtgctg cctactcggc caaagaagag ggcacgatct gtagaacggg      720

cctcaactcc atatagcata gattcagatt ctttgggaat ggagtgtatt atttcgggaa      780

gtgcctctcc aactctggca atcaacactg tgactaacaa agtaacattg tataacactg      840

atcaggatgg tagtgatagc ccacgcagta gccttaacaa cagtctctca gaccagagtt      900

tggcatctgt taatttgaac agtgttggaa gtgtgcatag ttatacaccg gtgacaagcc      960

atccagaatc agtctctcaa tcattaactc ctcagcagca accacagtac aaccttccag     1020

aaagagacaa gcaactactt ttctcagaat ataattttga agatcttagt gcctcatttc     1080

ggagccttta taagtcagtt tttgagcagt cacttagtca acaaggtttg atgaacatcc     1140

cttctgaatc ttcccagcag tcccacactt catgtaccta tcagcactct cccagcagta     1200

cagtgagcac tcacccacac agcaaccaaa gcagcctgtc caacagtcat ggcagtggcc     1260

tcaacaccac aggcagtaat tcggttgcac aggtctcact gtctcacccc cagatgcaca     1320

cacagccatc tccacatcct ccccatcgac cgcatggttt accgcagcat ccgcagcgtt     1380

ccccacaccc agcaccacac ccacagcaac acagccagct ccagtcccct cacccccagc     1440

atccctctcc acatcaacac atacagcacc atccgaacca tcagcatcag acgttaacac     1500

atcaggcacc cccaccccca caacaggtat cctgtaattc tggtgtttca aatgattggt     1560

atgcgacact tgatatgcta aaagaaagct gtcgaattgc cagcagtgtt aattggtcag     1620

atgtagacct ttcacagttt caaggtctga tggagagtat gagacaggca gatctcaaga     1680

actggtcttt agaccaggtt cagtttgccg atctttgttc ttctcttaat cagttcttta     1740

cacaaactgg ccttatacat tcacagagta atgttcaaca aaatgtttgt catggtgcca     1800

tgcatccaac aaaaccttcc caacacattg gaacaggaaa tttgtacata gattctaggc     1860

aaaatctccc tccttcagtg atgccacccc ctggttatcc tcatatccca caggcactca     1920

gcactccagg aacaacgatg gcaggccatc acagagccat gaaccagcag cacatgatgc     1980

cttcccaagc cttccagatg cggcgttccc tgcctccaga tgacatccag gatgactttg     2040

attgggattc aattgtgtag ggcttgtttc tgcaagacac cagaccctaa cgttaccttt     2100

ctgtgcagtg aagggaaagg tttaagagaa tccagttgag aaaacaaact tgctaatcac     2160

tttaccaatg ttatcaaaat tacttttgaa gacaatcaga aggattttag ctggataact     2220

tactgctttt atctgaccca agcaagtact acatgtttgt ctccctgcca gctgccctat     2280

gtagctccta actgttgtgt gatttggacg gctttttgca tatttgtgtc agtttgatgt     2340

taaccacaag tgccagactg atttttcaga cggagcctat tttgctgcaa gcagtttata     2400

taaagataca tatgtgtaaa tatatgtaca aaaattactg aaaggcttca gttttttcta     2460

attggattat tatgtcttga aagttattgt cagtttttat tccttgttag gctattttct     2520

gcaggatgct tttaactgat gtaggaaact gaaaggaaat agattttttc caaaacccag     2580

ttccccttat ttaatctttt ttagaaatgt gggtaatgaa ttctatctaa taagtcaagg     2640

aaaccagaat ttgacacact ccaacaatcc gaaggggcat gttgctcctg agcagcatga     2700

agaactgacc aaattggttt tgatgcttgg gggatcatag agtatttatg tctgcttttc     2760

taaatctgca ttataatagc tctaaaattt gttgattggt aagaaattgg gcattgcttg     2820

gctctttaaa cacatcagtg cttccacatt cacctatgta tttattattc aaaagtgtca     2880

ttttaatatt tattgctacc ttctgtgaat gcttagctcc tgtcgggttc attaaggaga     2940

aatgtgtctg aaagcacaga actattatta tttttttctt tttttgagat ggagtcttgc     3000

cctgttgccc aggctggagt gcagtggcac gatctcggct cactgcaacc tccgcctccc     3060

gggttcaagc aattctcctg cctcagcctc ccgagtagct gggagtgcag gtgcacaccg     3120

ccatgcctgg ctgatttttt gtattttagt agagatgggg tttcaccatg ttgcctgggc     3180

tggttgcaaa ctcttgagct caggcagtct gcctgcctca gcctcctaga gtgctgggat     3240

tacagacatg agccactgcg cctggcccag cgttactttt cttgataaga atttacagat     3300

aagacactca gagagacatt gtgtcattct ctatcatcac tccttttacc atgtgaatag     3360

atttctctgt cttggcattc ttgctgattc agacttatta gttaaatcgg atttttctgg     3420

aatttgaatc agatttcatt tgggcaacaa cagcagggca gggtttctaa agcaggtttc     3480

cccactcatc taggttgtct tgaaaggagg atagagccac ttacagtttt atttgcttca     3540

gtgtttaatg tagatattat gtggcctgct gtttctgttg tcttgtatgt ctgtgtatgc     3600

atgacatttg gtccctttct ttgaaatgca gcccctctta cgggtttttt agtggtggtg     3660

gtttgttttg tttcatatca tatcacagtt tgcatggact gattatctta gttttatgat     3720

aaaactagaa gaaatgaggg ttttttttta atgaatagat tttgaattga ttctttagac     3780

cccccaaaaa gtgtcagttc taatggggaa atatattcca tcaagtcaaa gagtaataac     3840

tgctcactag ttgcttttta gcatctctgg tcttatcagc catgctaaat cactttaatt     3900

agccttagtg attctatggt tgagtaatct ctacttgaac taaacaaaca tcttttgttt     3960

ctgtgtgtgt gtgctgtgtg tgagagtgtg cgcgcgcgtg tgtgtgtgtg tgttttaatg     4020

gagtgttgcc ttgaatgaat cactgggaag ccagccatgg taagggctgg tgaggttggg     4080

gagaaaggaa gagctttatg tttctctgtt gtttggaccc tacttggcat gaaaaaggaa     4140

gctcagttcc agccccttgg atcaacgaaa atcagaggat tctggaaagg cagccaactt     4200

gcgcctctta gaaggatcag aggcaagatg agatggcagc ctgcagagta aatgcttgaa     4260

aaaagagggg tgattttcaa tggtttgctt aagtcactgt tttctagaca ccaaaatagc     4320

tgttttgaaa ctgttttaat tgcttgggta gcaatgtgca ctttaaacaa tttggatatt     4380

ggaatgcagt ctcatactga gtgatttgag tagaaccact gatgatgatt ttataaattg     4440

tgtgaagcga atttcccatt tggcaatcat ttactgattt gcagtgatga atatttttat     4500

gagaatttaa acttagcaag aatggccatg gaggcaaagc cttcacccag acccatccca     4560

ctctcctgtg atccaggtgg tccaggagcc caggacaggc cttttctgtg ggccctggcc     4620

agacagggtt acctggtgag gtgcagagag tccctctagt ggccattttg tatggtagtt     4680

gctaatgcag aacaagttct gtcttgggct taaattgact gaagacttta gggggaaaga     4740

atagtaaatg catgtaaaca aatggggaca ctctgttcag gagaataatc cgactggcat     4800

ttgtggcagt ttttgaaatg taaatgtatt catgtgtgtt cttgtaaata cgtgtcgctc     4860

agatgtcctt tgaagtggga gggaatcaat ccggggataa tttcaaatgg aatagagtat     4920

tttgatattg ttcattcaga gggtgatgtg tacatatcta tattgtatat atgtgatgaa     4980

aatgcattgg ctttttgtgc agatacaacc tgctctctgt actgctgttg gacagtcagt     5040

gttttaatgt ttctacagtt ttgctattgc acgatttcat attttgcctc tatgatgaac     5100

ggcaaccatt atttgtaact gtttagtgct gtaaagaaat attccaagtg tcattaggat     5160

tgttgctgcc agaactgata tgcatgaatg gcacttaaaa taaatatatt atgttaactc     5220

tatttacaac aaaaaaaaaa aaaaaa                                          5246


<210>  1237
<211>  11191
<212>  DNA
<213>  homo sapiens

<400>  1237
ccgcgcgaac atggccgaag tcggcgagga cagcggcgcc cgcgccctgc tcgcgctgcg       60

ctcggcgccc tgcagcccag tgctgtgcgc cgcagccgcc gccgccgcct tccccgcggc      120

cgcacccccg ccggcccccg cgcagcccca gcctccgccc gggccgccgc cgccgccgcc      180

accgccgctg cctccgggcg cgatcgcggg cgcgggctcc tccgggggct cctccggggt      240

atccggggac tccgcggtcg cgggcgcggc gccggccctg gtggccgcgg cggccgcctc      300

ggtacggcag agcccggggc cggcgctggc gcggctggag ggccgcgagt tcgagttcct      360

catgcgccag cccagcgtca ccatcggccg caactcgtcg cagggctcgg tggacttgag      420

catgggcctg tccagcttca tctcgcggcg ccacctgcag ctcagcttcc aggagccgca      480

cttctacctg cgctgcctcg gcaagaacgg cgtcttcgtg gacggggcct tccagagacg      540

cggcgcgccc gccctgcagc tgcccaagca gtgtaccttc cggtttccca gcacggccat      600

caagatccag ttcacgtcgc tctatcacaa agaagaggcc ccagcctccc cgctgcggcc      660

actgtacccc cagatctccc ctctgaagat ccacatcccg gagccggacc tccggagcat      720

ggtcagcccc gtcccctccc cgacgggcac catcagtgtc cccaactcct gcccagccag      780

tccacgcggt gccggctcct ccagttaccg ctttgtgcag aacgtgacct cggacctgca      840

gctggcagca gagtttgcag caaaggccgc gtcggagcag caggcagaca cgtctggagg      900

agacagcccc aaggatgagt caaagccgcc gttctcctac gcgcagctga tcgtgcaggc      960

catctcctcc gcccaggacc ggcagctgac cctgagcggg atctacgccc acatcaccaa     1020

gcattacccc tactaccgga cggccgacaa aggctggcag aattctatcc ggcacaacct     1080

ctctttgaac cgttacttta tcaaagtccc acgttcccag gaggagcctg ggaaggggtc     1140

cttttggcga atagaccctg cctctgaagc caagctcgtg gaacaggcat tccggaaacg     1200

gaggcagagg ggtgtctcct gcttccgcac ccccttcggg cctctgtcct caaggagcgc     1260

tccagcttcg cccacacacc ccgggctgat gtcccctcgc tccggcggcc tgcagacccc     1320

agagtgcctg tctcgggagg gctcccccat tccacacgac cctgagtttg ggtccaagtt     1380

agcttctgtc ccagagtacc ggtattccca aagcgcaccc ggctcccccg tcagcgccca     1440

gccagtgatc atggccgtgc ctccccgacc gtccagcctc gtggccaagc ccgtggccta     1500

catgcccgcc tccatcgtaa cctcacagca gcccgcgggc cacgccatcc acgtcgtgca     1560

gcaggccccc accgtcacca tggtcagggt ggtcaccaca tctgccaact cggccaacgg     1620

atacatcctc accagccagg gcgcggcggg gggctcccat gatgcggcgg gcgcagccgt     1680

gctggacctg ggcagcgagg ccagaggcct ggaggagaaa cccaccattg cgtttgccac     1740

aatccccgcg gctggtggag tcatccagac ggtggccagc cagatggccc ccggggtccc     1800

cggacacacg gtcaccatcc tgcagcccgc cacacccgtg accctcgggc agcaccacct     1860

tccagtccgg gccgtgaccc agaacggaaa gcatgcggtt cccacgaaca gtttagccgg     1920

caacgcttac gccctcacca gccctttgca gctccttgcg acccaagcga gttcatccgc     1980

gccggtggtg gtcacccggg tgtgcgaggt ggggcccaag gagccagcag cagccgtcgc     2040

ggccacggcc accaccaccc cagccactgc caccaccgcc tctgcctccg cctcttccac     2100

tggagagccc gaggtcaaaa ggtcccgggt ggaggagccc agtggggctg taaccacacc     2160

ggctggagtg atcgcagctg ccggccccca ggggccaggc accggggagt gaggtcacct     2220

gcaacgcggg ggagtgggac tcacccagcg gcgaccccga agctggaccc ggcagctcag     2280

gcggccgcac ccacagacgg aggagaacag cccgcggcgg cctgtgggca tcggcggcac     2340

ctggacacac ccagcccttt ccatttgatc gcctgccttc ccgtggttta agacaaaaac     2400

acataaacaa gttcagacaa ctgattgtat gattctggga attctttgct ttcctttcct     2460

tctccctcgg caccacctcc tctccccagg cctccctgtc gggcatgggg aggaggttgg     2520

agctcagcat cttgaggaat gtgtcaagac agcccctccg ctccgcgctg cacggccagc     2580

cgcctttgtc cgggaggaca gacagaaacg cagcaaggca cacaccaagg ctgccgggga     2640

ggcccgggca ccggacagat gcctgttggg aagccaggag ctgccgagcc acggaccacc     2700

taacagcctc tccgcccgga acgtgacata gagagtgttg gcattaactc ggggggtgtc     2760

cgatttcact tcagacccca agtttttctt tgtttgttta aacatggaat tcagacttca     2820

ttgtacacct gagacagaca caaaagggat catgtatttt tgaggatttt acctgttgac     2880

gtctgatgac cggccgtagg tccagggttc ccgctgggtt taatcccctc gaagagtaaa     2940

cctgccgctc tgtctgataa cttcaagtaa gagcagcggc ttcctgggtt ggcgttcgcg     3000

gtggaaggtt cctaggatga aaggtgagcc tggatccgcc ggccgcagac atcgcgctgc     3060

tggggacgat tggggccgct gctctgcaga ccagaccttc ccgaattatc cgtggctccg     3120

atgtcccggt gctgacggcc acatggggac ctaacagtgc caaacgccat ctgctccagc     3180

tgctttttca cccagttgca gagtcctcac cactcccaca ttgatctgct gttttcaatt     3240

ggaaccattt ctcctgcctg aaactccagg gcccctccct gggctgtccg tgagcaggag     3300

accccacccc agcagcagtg gtgagcaggc ctgtgcctcc acgcccagcc cccgccaacg     3360

cgactggttt tgtttgccac acggtgagaa ccggaggacg ggatgctcca gccagttggg     3420

tggttctggg gtccctgagg aagccccctc ctgcacttcc attaagacag ccagtggttc     3480

ctggatcttt gtcaccaagc agcgttgagc cagagctgtc taatgctgag cccagctcag     3540

gaaggagaga ggagtccttc agtgtgtctt ggagatgcga agtgcgtcct cgtaaaggtc     3600

agctgtcagt tttgctggcc gctccggcgc tggctctcct gtccgggacc acaacgagaa     3660

acagcgacag attcgacgca gagctccgga agtgcctgag gagcagtggt tcttggaaat     3720

cgcccgtcct ccgcatcaca gcctctcacc agcaaagcag cctctgccca ggccctggcg     3780

ggagagctgc agagggaccc aggtgcctgg agggcatttg agggaggtgg ctggacaggt     3840

gtctccctga agaagaaggg agaacacttt tcaaagtgat tccgaggcag tgcgggagga     3900

cacacgtgct gtgcagtgga gtggggtcgc ccgtggcccc catcagagtc cccgtccccc     3960

aggacaagtg cagaacctct gtgggccccc tccttccacc tagatagaga aaaccccttg     4020

ttcggtttcc ttcccgtgtc ccgttgtttt tctaagcccc ccgaattgag tcgtttctat     4080

ggcactaacc tttccatggg aaataagctc tttgtggaag tccgtacctg ttgccctggg     4140

tgaggtttca gagaaacggg ggcaggatga acacagccgg ctgtcctggg tgcagttacg     4200

tccgtggagg gtgagagatt gcgccccgtt ccacacttgt gtcgcctgct gttgtctgtg     4260

ggccttttct ttccgtggtg cctggtgtgt gcgtgcatgg cgtgagagaa cggggggtgg     4320

gggttggagg tggctccccg acaccggtgc ctgtgtggcc tgagccggcg ccctcccggg     4380

agcgcccgtc acggggggcc tctgtgatta cctgctgctg ctctctcccg cgtggtgact     4440

atatgtcctc agggctgcct gtggccaccc tgatgggaga cctctgtttg cttctgggcc     4500

actgcaggtt ggcctcctca atacaagctg atgtctgcag ggagcgccgc gtgctgggat     4560

tgcaccacgt gttggtcaca aatcgaggtc gccttttggc ctggtctgct caggctggcc     4620

ctgacccacg tggtttcctg gcttctgaga cgcagcgcat tcttcctgtt agcggtagcg     4680

ttctctgatt tcactgcttc attgccaagg gcgtggaaag ggggtggtgg atggagccgg     4740

gaggtggcga gcacaggacc ccggggctgc attctgccgt gtggggttct gcactgtcta     4800

gcttctgcgg ggactgcaaa gagggatgaa gggacgtggt cctaggggtc ggctcagact     4860

cggagcaggg cagggagagg agggcaagga gaggaggcct gggtcctgga tccactgctc     4920

tgggctcata accatgagat tttgaaagag tttttggtca tctgagcagg taccatgcct     4980

ggctcatgcc ggaacttgtc ttggaaccgg tagccagagg cccaggaagg gacagggccc     5040

aaaagggttg catgtcccgg ccacaaagcc ctccctgtgt gccctgagcc agcccagcaa     5100

gcgcctccca gccaggcgct ttcgcagaag caagagcaca ggccaggggg accgggagag     5160

cctcagcccc cagcctgggc ggcctgtgac cctgagccgt gtggagccag gacccaagaa     5220

ccttctctag gttctcaagg gtgagctgac ccgggcaatg tgcaggaatg tggggagcaa     5280

aagtagctga ttccagcccc gttctggggt cactggggag gcagaggctg agggcctgtt     5340

ctctggtcac cagggactgg gggcacggtc cacagcggat gagaacagca ggtcacagta     5400

gtggctttgg gaagggcccc tcctgctttg ccctgttcgg aaaggggctc cctcagagcc     5460

cctgggccca gtaacccgct tctgtctcct gactcctgct ggataaattg ccaggtttat     5520

caaatacaag aaaacacctg ctttggctag gaggtaagtc ccaaaaagaa cgtcttaagt     5580

agagcaaagg catccaccga ggccatttgg tggcccctgg gaagtgggga agcagggcct     5640

gagcgtcccc aggctgctag ggcagcagct ggctcagggc acactctctc gtgccagctt     5700

ctgccaccag cccagtgtcc acggagccgc ggggccagag gagctcaggg agacctggct     5760

gtctagggca tggtacccag tatcccggtg tgtgcccatc ctcagccact tgtgtctttc     5820

tttccatgtg ggagttctcc cggtgacacc tgccctccgt tgagggtgga atctgtcact     5880

catgcctttg agggacccag atggaccatc cctcttctgc ttgctttcta cattcctaaa     5940

aacctcaacg ttaatccctc accagtcggg ccgagtgtgg cctcatggtt ctgccgcggc     6000

ccagtcttct cccactggct tcacgctaga gggcgccatg cgctctgggt gaaatgagac     6060

gctggtgtgg ggtccccatg tagagaccct caggtcccta tccagagacc ctccaggcag     6120

tgctgggaag acactggtgg cggggaccat gaccaggcgg gtggagccat gtgtgtctca     6180

cacctgccgc ccctcacttt ccttcccgag gtctggtagg tcctctttgg gatttgctgt     6240

ttatttgtat ctcccttttc tttgatttaa gaacaatgcc aagtgaaaaa gctgggaatg     6300

aatttctgag ttgctgagtg ttccctgctc ctaggtacca cgctctgtgc ttctcaggca     6360

gggaggagat ggattcggtg gagttgggcc aggacggggg cttcaccctg ccccctccag     6420

actgccgaag cccccaagaa gttttgagcc cagctgggcc tcgcctcccc ggctcctggg     6480

tccattttct gtactggttt gagatcacag gcatcattca gcgaatgctc ttgtgtcctc     6540

tgcataaaga gggccctccc tggagcaccc ccggggagct gggactctcc agaaagcccc     6600

gggtgagggc tccgtcttga gagagagaga aatcccttct ttgggcgatt cagtgagttc     6660

aggaggagga ggaagctttt ccttggcttt gaaatcagtg tttttatgga gacaaagaac     6720

agacctcagt gggaaaaatg aaaacgtaat ggaacacggg gaggtgtcgg agaagaaagg     6780

attttcccct tcgctttcag agccggcggg agtgcaggtc tgttttgctt cagaagcctc     6840

acattctgct ttgcccttga gtgacttcat gcgggatgag gaactgttga cccctctaga     6900

gaggacaccc caagtccatc ctgggctcct cctcacccct ctgagaaagc ccccctaaaa     6960

aaaggcttca gagtcaccgg catgccgcct cacgttgcag gacggaatcg cgcgctcctc     7020

acgctggagt aagttacgaa acatgatcgt caggctcttt gcaaacgcag agccccagaa     7080

cgctggatgg aggcctcctc ggccctgcgg gcggcctggc tgcggtaggt ctgctgcaag     7140

gagccaccac ggggactgcg ccacactcct gatgaaaacg tgtttaccca cagcctcgcc     7200

tcgagcctcc ttgacaatac cgctgcttca aagcaatatt atttaatgag aatactttac     7260

attgctcaca tgtgctgcta tgaagacagg attagtctgt agacgggact cagctccaga     7320

ggttcctggg taatgtattg tggctcttgg aaatgagggt agaatttgaa atataacaaa     7380

tggtctctcg cccggttctg tcccttattt ttagattgtt ttcctgcatc ttacaatttc     7440

cttttctttt caaagttcct ttctccaggc ctgtttttca gtgctcagga cacggttttc     7500

atcacatact tactgttttt ttggttgggt tttgatacga aaagctgcta cgtttggtga     7560

ccagagggag ggtttggaat ctgtgctttg caggggatct cggtgggtac cgcggcccct     7620

cgcagggtgg cgagtggggt ccgtgcctcg agaagggggc ccttacccac accgtgcggc     7680

ttgaattctg tcggagttga atctgtggaa aggattgtcc cattagagct gctgcgtcct     7740

ttcctctgtc ctccctgtca cccaaacccc gaagtcacag ctgcttagaa gaatgggatt     7800

ttggggatac aaccacacac atttccctct ggactgaaat tttaaaaaca gacccatttc     7860

actgacttct tttttttttt tttttttttt ttttttttga gacggagtct cgctctgtcg     7920

cccaggctgg agtgcagtgg cgtgatctcg gctcactgca agctccgcct cccgggttca     7980

cgccattctc ctgcctcagc ctcccgagta gctgggacta caggcgcccg ctaccacgcc     8040

cggctaattt tttgtatttt tagtagagac ggggtttcac cgtgttagcc aggatggtct     8100

cgatctcctg acctcgtgat ccgcccgcct cggcctccca aagtgctggg attacaggcg     8160

tgagccaccg cgcccggccc actgacttct ttagggaaaa tagtttcagt cttgggttgt     8220

cttgtgagcc cacgggcatg ggaccctgtc tctgctgggc ttttccggcc ccgtcccagc     8280

tcctcctcag gcagaggctg cagccctcag ctctgctgct ggatggaaca tttcaacccc     8340

ctccgggaag gtgggcaggg tggagggccc agggctaggc ctgccatgca ccatgagcag     8400

gggtgctacc tgggtgtgtg aagttgggct ggcttttcct ggaggtgggt gagaaggctc     8460

tccgggcaaa tcagaaggcc acgagagaga gaggagcggg gagagtggtg aggaggattc     8520

gtctctgact gatgaacctc gccgtgcctg tctgtcacat ccaagtctgt gccagctgct     8580

gggaggtcag actcctgccc tgagaaacag cccagtcctt ggagaatgaa accctgaggg     8640

tcagtgagtg gaggccttcc ctcggggcca gccattcccg ggaggcctga gtgtgacctg     8700

gaagctctgt gggtcaccaa gactggcatt ttccttgtat ttttgtgcag ggctgaagtg     8760

agcgttcctc ctctgaattg gtgaggcttt ggaaattttt tgtttcttct actcatccta     8820

atggctggtt ttggctgccc ggagtatcag agaatatcac taagagggca gtcagtttat     8880

ttttaggcat ctttctttct gtccagggag aaacccctcg gaagaatctt agtcactctt     8940

tgcacctgcc ctgtcattct cgccatgggg aaaatgcgtt gaaaagaaaa ataccggggc     9000

cagggagaag ccgtgaatgt atttatttgc tttggtgaag ctgctgaaca ctggctgcgg     9060

agggcccccc gcccccatcc cgcttcaggc cccagtgacc cagttgcgtc ttaagttcca     9120

tcgtccagat ttcaggccac cagaggctgc caaaggtgac tgaagcggtc tccaagtcac     9180

tctgtcacca cttttttttt ttttgagatg gagtctcgct ctatcgccca ggctggagtg     9240

cagtggccca atctcggctc actgcaacct ccgcctccca ggttcgagcg aattctcctg     9300

cctcaacctc ccaagtagct gggattacag gcacctgcca ccacacccgg ctaatttttg     9360

tatttctaat agagatgaga gtgttaccat gttggtcagg ctggtcttga actcctgacc     9420

tcaggtgatc tgcccacctc aacctcccaa agtgctggga ttataggcat gagccaccgc     9480

gcctggcctc tgtcactttt tttgctcctt acccagtttt tgttttttgt tgttttgttt     9540

tgttttagcg tgatactaca atggaaagac tcctagttgg ttattcttta tctcggattc     9600

ttttttctgg aattgtttgc tcatttgagt ggttggtggt ttgccctgtg tcagacacgg     9660

tgaaaagagt gcaggaaagc tggggccagg ggaagcgaag tggcttcaat ccgggctgac     9720

agccaagaag agttttcctc ccttcggtga cagggcctgc ccctccgagt ctagaggtaa     9780

aagcagcttc tagaactggc ccctaagtct ccaaatgtgt tggctaagct gaaatgagag     9840

actctgaatt agagtttttg tttgtttgtt tgttctctgc atgaagttca caggcctgta     9900

tggatgttaa attgtgtcta tagcctctaa atctccaggt taactggtcc agattttttt     9960

tttttaatca gtaacaatgg gaatttaaaa tcaaatattt ggccaggtgc ggtggctcat    10020

gcccgtaatc ccagcacttt gggaggccga ggcaggcgca tcacctgagg agtttgagac    10080

cagcctgacc aacatggtga aatcctgtct ctactaaaaa tacaaaaaat tagccaggcg    10140

tggtggcgtg tgcctgtaat cccagctacc agggaggctg aggcatgaga atcgcttgaa    10200

cctgggagat ggaggttgca gtgagccgag atcatgccac tgcactccag cctgggcaac    10260

agagggagac tctgtctcaa aaataataat caaatcaagt attttaagtt tggctcttct    10320

ttttttcaag aaaggctttt tggataccta gaataccttc atgtatgtgg cttgatttct    10380

gtttcaggaa aaggggggcg ggaggagaga caacagccgt gttccagagt ctgtcctgag    10440

atgtcgctga gtccagacac ttgggctgca cgtgccctgc agatgacaaa ggccggcagc    10500

tcagcacacg tgcaggaggg gttaaagcca atattgagtt tttgttcttg ttgttttaat    10560

ctgaacgatt attctcctgt aaaaataatt tgggaggggc gggtgttgtt cggtgtgtgt    10620

gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt attttttttt ttacagtggc gcctgtctaa    10680

agtatttttc acaacatgtt tgataatcag tgctttaaaa agcagcagtg tcctatgaag    10740

tggaaatgtc agttctagag cattggatgt gaagttctgg tcatgtcacc ttgcgtgtct    10800

caccctggag gagtgaaggt gggcgcccgg cgggggggtg tggctgcacc ccagcaccgg    10860

gagggggcac gcacgacacc agaggaaggg acagccccac ccatgtcaac agcaggcaac    10920

ctgtgttttc atttcaagtg ggatacagta tttttttaat aaggagccat actttttttt    10980

aagagtttga gatctgaatg tgatttctaa ttgtatcaga cgttaatgtt ttaaagctat    11040

aacaaagttt aaaatttcta ctttttgttt ttcatttatt ttaactgttc ttttatctat    11100

taaattgttg tatgtggatg gggaagtttt gtttctcctc ttagcatttg tttctataac    11160

cagaaataaa attctatatt aaagaaatga c                                   11191


<210>  1238
<211>  3665
<212>  DNA
<213>  homo sapiens

<400>  1238
tttcaaacag cggaacaaac tgaaagctcc ggtgccagac cccacccccg gccccggccc       60

gggaccccct cccctcccgg gatcccccgg ggttcccacc ccgcccgcac cgccggggac      120

ccggccggtc cggcgcgagc ccccgtccgg ggccctggct cggcccccag gttggaggag      180

cccggagccc gccttcggag ctacggccta acggcggcgg cgactgcagt ctggagggtc      240

cacacttgtg attctcaatg gagagtgaaa acgcagattc ataatgaaaa ctagcccccg      300

tcggccactg attctcaaaa gacggaggct gccccttcct gttcaaaatg ccccaagtga      360

aacatcagag gaggaaccta agagatcccc tgcccaacag gagtctaatc aagcagaggc      420

ctccaaggaa gtggcagagt ccaactcttg caagtttcca gctgggatca agattattaa      480

ccaccccacc atgcccaaca cgcaagtagt ggccatcccc aacaatgcta atattcacag      540

catcatcaca gcactgactg ccaagggaaa agagagtggc agtagtgggc ccaacaaatt      600

catcctcatc agctgtgggg gagccccaac tcagcctcca ggactccggc ctcaaaccca      660

aaccagctat gatgccaaaa ggacagaagt gaccctggag accttgggac caaaacctgc      720

agctagggat gtgaatcttc ctagaccacc tggagccctt tgcgagcaga aacgggagac      780

ctgtgcagat ggtgaggcag caggctgcac tatcaacaat agcctatcca acatccagtg      840

gcttcgaaag atgagttctg atggactggg ctcccgcagc atcaagcaag agatggagga      900

aaaggagaat tgtcacctgg agcagcgaca ggttaaggtt gaggagcctt cgagaccatc      960

agcgtcctgg cagaactctg tgtctgagcg gccaccctac tcttacatgg ccatgataca     1020

attcgccatc aacagcactg agaggaagcg catgactttg aaagacatct atacgtggat     1080

tgaggaccac tttccctact ttaagcacat tgccaagcca ggctggaaga actccatccg     1140

ccacaacctt tccctgcacg acatgtttgt ccgggagacg tctgccaatg gcaaggtctc     1200

cttctggacc attcacccca gtgccaaccg ctacttgaca ttggaccagg tgtttaagcc     1260

actggaccca gggtctccac aattgcccga gcacttggaa tcacagcaga aacgaccgaa     1320

tccagagctc cgccggaaca tgaccatcaa aaccgaactc cccctgggcg cacggcggaa     1380

gatgaagcca ctgctaccac gggtcagctc atacctggta cctatccagt tcccggtgaa     1440

ccagtcactg gtgttgcagc cctcggtgaa ggtgccattg cccctggcgg cttccctcat     1500

gagctcagag cttgcccgcc atagcaagcg agtccgcatt gcccccaagg tttttgggga     1560

acaggtggtg tttggttaca tgagtaagtt ctttagtggc gatctgcgag attttggtac     1620

acccatcacc agcttgttta attttatctt tctttgttta tcagtgctgc tagctgagga     1680

ggggatagct cctctttctt ctgcaggacc agggaaagag gagaaactcc tgtttggaga     1740

agggttttct cctttgcttc cagttcagac tatcaaggag gaagaaatcc agcctgggga     1800

ggaaatgcca cacttagcga gacccatcaa agtggagagc cctcccttgg aagagtggcc     1860

ctccccggcc ccatctttca aagaggaatc atctcactcc tgggaggatt cgtcccaatc     1920

tcccacccca agacccaaga agtcctacag tgggcttagg tccccaaccc ggtgtgtctc     1980

ggaaatgctt gtgattcaac acagggagag gagggagagg agccggtctc ggaggaaaca     2040

gcatctactg cctccctgtg tggatgagcc ggagctgctc ttctcagagg ggcccagtac     2100

ttcccgctgg gccgcagagc tcccgttccc agcagactcc tctgaccctg cctcccagct     2160

cagctactcc caggaagtgg gaggaccttt taagacaccc attaaggaaa cgctgcccat     2220

ctcctccacc ccgagcaaat ctgtcctccc cagaacccct gaatcctgga ggctcacgcc     2280

cccagccaaa gtagggggac tggatttcag cccagtacaa acctcccagg gtgcctctga     2340

ccccttgcct gaccccctgg ggctgatgga tctcagcacc actcccttgc aaagtgctcc     2400

cccccttgaa tcaccgcaaa ggctcctcag ttcagaaccc ttagacctca tctccgtccc     2460

ctttggcaac tcttctccct cagatataga cgtccccaag ccaggctccc cggagccaca     2520

ggtttctggc cttgcagcca atcgttctct gacagaaggc ctggtcctgg acacaatgaa     2580

tgacagcctc agcaagatcc tgctggacat cagctttcct ggcctggacg aggacccact     2640

gggccctgac aacatcaact ggtcccagtt tattcctgag ctacagtaga gccctgccct     2700

tgcccctgtg ctcaagctgt ccaccatccc gggcactcca aggctcagtg caccccaagc     2760

ctctgagtga ggacagcagg cagggactgt tctgctcctc atagctccct gctgcctgat     2820

tatgcaaaag tagcagtcac accctagcca ctgctgggac cttgtgttcc ccaagagtat     2880

ctgattcctc tgctgtccct gccaggagct gaagggtggg aacaacaaag gcaatggtga     2940

aaagagatta ggaacccccc agcctgtttc cattctctgc ccagcagtct cttaccttcc     3000

ctgatctttg cagggtggtc cgtgtaaata gtataaattc tccaaattat cctctaatta     3060

taaatgtaag cttatttcct tagatcatta tccagagact gccagaaggt gggtaggatg     3120

acctggggtt tcaattgact tctgttcctt gcttttagtt ttgatagaag ggaagacctg     3180

cagtgcacgg tttcttccag gctgaggtac ctggatcttg ggttcttcac tgcagggacc     3240

cagacaagtg gatctgcttg ccagagtcct ttttgcccct ccctgccacc tccccgtgtt     3300

tccaagtcag ctttcctgca agaagaaatc ctggttaaaa aagtcttttg tattgggtca     3360

ggagttgaat ttggggtggg aggatggatg caactgaagc agagtgtggg tgcccagatg     3420

tgcgctatta gatgtttctc tgataatgtc cccaatcata ccagggagac tggcattgac     3480

gagaactcag gtggaggctt gagaaggccg aaagggcccc tgacctgcct ggcttcctta     3540

gcttgcccct cagctttgca aagagccacc ctaggcccca gctgaccgca tgggtgtgag     3600

ccagcttgag aacactaact actcaataaa agcgaaggtg gacatgaaaa aaaaaaaaaa     3660

aaaaa                                                                 3665


<210>  1239
<211>  3551
<212>  DNA
<213>  homo sapiens

<400>  1239
tttcaaacag cggaacaaac tgaaagctcc ggtgccagac cccacccccg gccccggccc       60

gggaccccct cccctcccgg gatcccccgg ggttcccacc ccgcccgcac cgccggggac      120

ccggccggtc cggcgcgagc ccccgtccgg ggccctggct cggcccccag gttggaggag      180

cccggagccc gccttcggag ctacggccta acggcggcgg cgactgcagt ctggagggtc      240

cacacttgtg attctcaatg gagagtgaaa acgcagattc ataatgaaaa ctagcccccg      300

tcggccactg attctcaaaa gacggaggct gccccttcct gttcaaaatg ccccaagtga      360

aacatcagag gaggaaccta agagatcccc tgcccaacag gagtctaatc aagcagaggc      420

ctccaaggaa gtggcagagt ccaactcttg caagtttcca gctgggatca agattattaa      480

ccaccccacc atgcccaaca cgcaagtagt ggccatcccc aacaatgcta atattcacag      540

catcatcaca gcactgactg ccaagggaaa agagagtggc agtagtgggc ccaacaaatt      600

catcctcatc agctgtgggg gagccccaac tcagcctcca ggactccggc ctcaaaccca      660

aaccagctat gatgccaaaa ggacagaagt gaccctggag accttgggac caaaacctgc      720

agctagggat gtgaatcttc ctagaccacc tggagccctt tgcgagcaga aacgggagac      780

ctgtgcagat ggtgaggcag caggctgcac tatcaacaat agcctatcca acatccagtg      840

gcttcgaaag atgagttctg atggactggg ctcccgcagc atcaagcaag agatggagga      900

aaaggagaat tgtcacctgg agcagcgaca ggttaaggtt gaggagcctt cgagaccatc      960

agcgtcctgg cagaactctg tgtctgagcg gccaccctac tcttacatgg ccatgataca     1020

attcgccatc aacagcactg agaggaagcg catgactttg aaagacatct atacgtggat     1080

tgaggaccac tttccctact ttaagcacat tgccaagcca ggctggaaga actccatccg     1140

ccacaacctt tccctgcacg acatgtttgt ccgggagacg tctgccaatg gcaaggtctc     1200

cttctggacc attcacccca gtgccaaccg ctacttgaca ttggaccagg tgtttaagcc     1260

actggaccca gggtctccac aattgcccga gcacttggaa tcacagcaga aacgaccgaa     1320

tccagagctc cgccggaaca tgaccatcaa aaccgaactc cccctgggcg cacggcggaa     1380

gatgaagcca ctgctaccac gggtcagctc atacctggta cctatccagt tcccggtgaa     1440

ccagtcactg gtgttgcagc cctcggtgaa ggtgccattg cccctggcgg cttccctcat     1500

gagctcagag cttgcccgcc atagcaagcg agtccgcatt gcccccaagg tgctgctagc     1560

tgaggagggg atagctcctc tttcttctgc aggaccaggg aaagaggaga aactcctgtt     1620

tggagaaggg ttttctcctt tgcttccagt tcagactatc aaggaggaag aaatccagcc     1680

tggggaggaa atgccacact tagcgagacc catcaaagtg gagagccctc ccttggaaga     1740

gtggccctcc ccggccccat ctttcaaaga ggaatcatct cactcctggg aggattcgtc     1800

ccaatctccc accccaagac ccaagaagtc ctacagtggg cttaggtccc caacccggtg     1860

tgtctcggaa atgcttgtga ttcaacacag ggagaggagg gagaggagcc ggtctcggag     1920

gaaacagcat ctactgcctc cctgtgtgga tgagccggag ctgctcttct cagaggggcc     1980

cagtacttcc cgctgggccg cagagctccc gttcccagca gactcctctg accctgcctc     2040

ccagctcagc tactcccagg aagtgggagg accttttaag acacccatta aggaaacgct     2100

gcccatctcc tccaccccga gcaaatctgt cctccccaga acccctgaat cctggaggct     2160

cacgccccca gccaaagtag ggggactgga tttcagccca gtacaaacct cccagggtgc     2220

ctctgacccc ttgcctgacc ccctggggct gatggatctc agcaccactc ccttgcaaag     2280

tgctcccccc cttgaatcac cgcaaaggct cctcagttca gaacccttag acctcatctc     2340

cgtccccttt ggcaactctt ctccctcaga tatagacgtc cccaagccag gctccccgga     2400

gccacaggtt tctggccttg cagccaatcg ttctctgaca gaaggcctgg tcctggacac     2460

aatgaatgac agcctcagca agatcctgct ggacatcagc tttcctggcc tggacgagga     2520

cccactgggc cctgacaaca tcaactggtc ccagtttatt cctgagctac agtagagccc     2580

tgcccttgcc cctgtgctca agctgtccac catcccgggc actccaaggc tcagtgcacc     2640

ccaagcctct gagtgaggac agcaggcagg gactgttctg ctcctcatag ctccctgctg     2700

cctgattatg caaaagtagc agtcacaccc tagccactgc tgggaccttg tgttccccaa     2760

gagtatctga ttcctctgct gtccctgcca ggagctgaag ggtgggaaca acaaaggcaa     2820

tggtgaaaag agattaggaa ccccccagcc tgtttccatt ctctgcccag cagtctctta     2880

ccttccctga tctttgcagg gtggtccgtg taaatagtat aaattctcca aattatcctc     2940

taattataaa tgtaagctta tttccttaga tcattatcca gagactgcca gaaggtgggt     3000

aggatgacct ggggtttcaa ttgacttctg ttccttgctt ttagttttga tagaagggaa     3060

gacctgcagt gcacggtttc ttccaggctg aggtacctgg atcttgggtt cttcactgca     3120

gggacccaga caagtggatc tgcttgccag agtccttttt gcccctccct gccacctccc     3180

cgtgtttcca agtcagcttt cctgcaagaa gaaatcctgg ttaaaaaagt cttttgtatt     3240

gggtcaggag ttgaatttgg ggtgggagga tggatgcaac tgaagcagag tgtgggtgcc     3300

cagatgtgcg ctattagatg tttctctgat aatgtcccca atcataccag ggagactggc     3360

attgacgaga actcaggtgg aggcttgaga aggccgaaag ggcccctgac ctgcctggct     3420

tccttagctt gcccctcagc tttgcaaaga gccaccctag gccccagctg accgcatggg     3480

tgtgagccag cttgagaaca ctaactactc aataaaagcg aaggtggaca tgaaaaaaaa     3540

aaaaaaaaaa a                                                          3551


<210>  1240
<211>  6803
<212>  DNA
<213>  homo sapiens

<400>  1240
agcagttcag agccccagtt gcagacgact tgtcctgcca ccaccatgag ttctgaatgt       60

gatggtggtt ccaaagctgt gatgaatggc ttggcacctg gcagcaatgg gcaagacaaa      120

gcaactgccg accctttacg cgcacgctct atttctgctg ttaaaatcat tcctgtgaag      180

acagtgaaaa acgcctcagg cctagttctc cctacagaca tggatcctac aaaaatctgc      240

actgggaagg gagcggtgac tctccgggcc tcgtcttcct acagggaaac cccaagcagt      300

agccctgcga gccctcagga aacccggcaa cacgaaagca aaccaggtct ggagccagag      360

ccttcttcag cagatgagtg gaggctttct tccagtgctg atgccaatgg aaatgcccag      420

ccctcttcac tcgctgccaa gggctacaga agtgtgcatc ccaaccttcc ttctgacaag      480

tcccaggatg ccacttcctc cagtgcagcc cagccggagg taatagttgt ccctctctac      540

ctggttaata ctgacagagg gcaagaaggc actgccagac ctccaacacc tctggggcct      600

cttggctgcg tccccacaat cccagcgact gcctctgccg cctcacctct gaccttcccg      660

actctagatg atttcattcc ccctcatctg cagaggtggc cccaccacag ccagccagcc      720

cgcgcctctg gctcctttgc ccccattagc cagacgccac catccttctc accaccacct      780

ccgctggtcc ctcctgcccc ggaggacctc cgcagagtct cggagcctga cctcacggga      840

gctgtttcga gtaccgattc cagtcctcta ctaaatgaag tttcttcttc ccttattgga      900

actgattccc aagcctttcc atcagttagc aagccttcat ccgcctatcc ctccacaacg      960

attgtcaatc ctactattgt gctcttgcaa cacaatcgag aacagcaaaa acgactcagt     1020

agcctttcag atcctgtctc agaaagaaga gtgggagagc aggactcagc accaacccag     1080

gaaaaaccca cctcacctgg caaggctatt gaaaaaagag caaaggatga cagtaggcgg     1140

gtggtgaaga gcactcagga cttaagcgat gtttccatgg atgaagtggg catcccactc     1200

cggaacactg agagatcaaa agactggtac aagactatgt ttaaacagat ccacaaactg     1260

aacagagaca ctcctgaaga aaacccttat ttccctacgt acaaattccc tgaacttcct     1320

gaaatccagc aaacttccga agagacaaag tcttgctctg tcatgtcacc caggctggag     1380

tgcagtggta cagtcatagc tcactgcagc ctcaaactcc tagactcaag caatcctccc     1440

acctcagcct cccaagtagc tgggactgca gatgatgatt cagatctgta ctctcccaga     1500

tactcatttt ctgaagacac aaaatctccc ctttctgtgc ctcgctcaaa aagtgagatg     1560

agctacattg atggtgagaa ggtagtcaag aggtcggcca cactacccct cccagcccgc     1620

tcttcctcac tgaagtcaag ctcagaaaga aatgactggg aacccccaga taagaaagta     1680

gacacaagaa aatatcgtgc agagcccaag agcatttacg aatatcagcc tggcaagtct     1740

tccgttctga ccaacgaaaa gatgagtcgg gatataagcc cagaagagat agatttaaag     1800

aatgaacctt ggtataaatt cttttcggaa ttggagtttg ggaaaccgcc tcccaaaaag     1860

atatgggatt atactcctgg agactgctct atccttccta gagaggatag aaagactaat     1920

ctagacaaag atctcagcct ctgccagaca gagttagagg cagatttaga aaaaatggag     1980

acgcttaata aagcacccag tgcaaacgtg ccacagagct cagccatcag ccctactccg     2040

gaaatttctt cagagactcc tggatatata tattcttcca acttccatgc agtgaagagg     2100

gaatcagacg gggctcctgg ggatctcact agcttggaga atgagagaca aatttataaa     2160

agtgtcttgg aaggtggtga catccctctt cagggcctga gtgggctcaa gcgaccatcc     2220

agctctgctt ccactaaaga ttcagaatcg ccaagacatt ttataccagc tgattacttg     2280

gaatccacgg aagaatttat tcgaagacgt catgatgata aagagaaact tttagcggac     2340

cagagacgac ttaaacgcga gcaagaagag gctgatattg cagctcgacg ccacacaggc     2400

gtcattccga cgcaccatca gtttatcact aatgagcgct ttggggacct cctcaatata     2460

gacgatactg caaaaaggaa atctgggtca gagatgagac ctgccagagc caaatttgac     2520

tttaaagctc agacactaaa ggagcttcct ctgcagaagg gagatattgt ttacatttat     2580

aagcaaattg atcagaactg gtatgaagga gaacaccacg gccgggtggg aatcttccca     2640

cgcacctaca tcgagcttct tcctcctgct gagaaggcac agcccaaaaa gttgacacca     2700

gtgcaggttt tggaatatgg agaagctatt gctaagttta actttaatgg tgatacacaa     2760

gtagaaatgt ccttcagaaa gggtgagagg atcacactgc tccggcaggt agatgagaac     2820

tggtacgaag ggaggatccc ggggacatcc cgacaaggca tcttccccat cacctacgtg     2880

gatgtgatca agcgaccact ggtgaaaaac cctgtggatt acatggacct gcctttctcc     2940

tcctccccaa gtcgcagtgc cactgcaagc ccacagccat ggcgcgaaga gagtggacaa     3000

tatgagagga aagcagagag gggggcaggc gaaagaggcc ctggtggacc caagatctct     3060

aagaagagct gcttgaagcc ttcagacgtg gtcaggtgcc tgagtactga acagagactc     3120

tcagatctca acacccctga ggagagccgg cccggcaagc ccctgggtag cgcttttcca     3180

ggaagtgagg ctgagcagac agagcggcat agaggtggcg agcaggcggg gaggaaagct     3240

gctcggagag gtgggagcca gcaacctcaa gcccagcagc gaagagtcac ccccgacagg     3300

agtcaaacct cacaagattt atttagctat caagcattat atagctatat accacagaat     3360

gatgatgagt tggaactccg cgatggagat atcgttgatg tcatggaaaa atgtgacgat     3420

ggatggtttg ttggtacttc aagaaggaca aagcagtttg gtacttttcc aggcaactat     3480

gtaaaacctt tgtatctata agaagactga aaaccatgga gattattttt attggaggag     3540

gaagcatcat tcatgaaccg atctttttag ttgagtcagt aggaaaatta atacagtgga     3600

taaagtaaga agcaaaagac agggacagag aagtgttgtg tttaaaaccc aagcctgtct     3660

aaggttactg tgtattagac agggccgaac tagtgtgctg agcaaaaaga attgaagcaa     3720

attgtattta cttagccgct tctgggagcc acttcagcct ttcccctccc ctccacttct     3780

tgggtaatct gacctgaagc atagtccagg agcagagtta gccagaaatg cctcctgctg     3840

ccccagcctt agagagctcc catctcaatc attgagcctg aaggcttcaa gcccaagaat     3900

gcaacaagac ccccagccta catttctcag ctcccctgga gccagctgat cctgtaacgc     3960

tgctggaggt cagtctgagc taccaagact gtccctagac aaaggtggag tcccccacac     4020

tgcccaagac caaatccctc actcaacctg ctgaggtgtg gatggggaaa cagaggcaaa     4080

actgaggcac ctgatgcatt cagcctgctg tgcagcagtg ccattgactg ccctgatgtt     4140

cagagagaaa cgcacacaag gtttgcccat gagaattggg gagcagatgg ccaagcagat     4200

aggttatgtc tgttttctga gtgatgaagt caggaagccc tgtggctctg gaggccactt     4260

gtggttcatt cttttcccat atccttggct tttagaaatg gttaccttca ggacagtgca     4320

gctgcattta tcagagcact attgctaagt tttcttttct ggcttgtgtt tttctgggac     4380

agtttagaat tgggaggcct attctcatag aacaccaaaa atgatgttca gtgattcatt     4440

taacatacac caatgtactc tggctgctgg ggggacaacc ataagcaaga catgcccagg     4500

gtttgccgtg gctccagatc tactccctgt aggagttcaa ggatcacaca aacggtagta     4560

accagggttg tgaatctgag tacaccctgg caaggcttct cttcagactg aagcagcaat     4620

tctgccacta ccagcagcaa ccaggacgtc tgttctttgt gggggccaga tcagaagaga     4680

gaggcccctg tgacgcccgg gctgcttggt cacaactctg tccaattcaa ggatgtttat     4740

cggcctctct tagatcctga gtgagacaaa tacagaaatg acccattccc tgcccaccag     4800

aaactcagag gtgattgggg agactgacac aggaaaatga acttaatcaa gagagactgt     4860

gatatgtgct aagaagggtg tgagggaggg agagatgaat tttccctgga gggatcctag     4920

aaagcattgt catattgcca tctccattag ctcactttta aacaactagg gtgctggaag     4980

aacctttgtc tgagggtagt tcatagctgg aaatacttgg aatattttcc agagtctcta     5040

aactctcatc ttcccccaca gatacacatc caagctcaca aataggagta gcaattctag     5100

gtggtagggt tgtgtacgga acccctggct gtctgcatat atctcagaat taccccagga     5160

ccattgtccc aaagtctaga gtctttacag gtaggcaaaa tttgttttca atgcctgtgc     5220

ctcagctgct gtcacaaata cccatcttag gatcccatca gcttcccatc ccccaccaga     5280

cagccacagt accctcactt tctccctatt gttctttcaa atcctgttct caggaaagaa     5340

actgccacta attcattcac actaaggtgt aaatgattga taataggaat gagttacctc     5400

ttcccacaga catttgtttt taagtatgac agagcagggc cttaatccca agggaaaagg     5460

ttatggaact ggagggggtg agctttctgg gtagaaggag acttcctgaa tttccttaaa     5520

acccagtaag agtaagacct gttgttttgg aaggtctgct ccaccatcta agagcactgt     5580

tttttttttt ttgttgttgt tgttgtttta cggtctctga gggaatatag taaaaatgca     5640

tatgcacgtg caatttgcac ggcagcattt caccgattgt ggactgtatt ggctaatgtg     5700

tttcctggtc tttagatgca aaccattaat aacactatct tatctcatag ttttttcagg     5760

ggtgcttctt gattagtagg gaattttgaa cacctcttta aatacagcta gaaaataaaa     5820

ccaatttgta aagccacatt tgcatatgat gccagcctca cgcatttgta tatctccaga     5880

aattcaggta tgcctcacca atttgcccgt ctttaataaa atcttgtgtt aaaatttgca     5940

tcacgtcgcc ttcctatgta tgacgaaaca agaaacagag atttccaatt gctcttttgt     6000

cttcagacat ttagtaatat aaagtaccta tttttatgct gaaatgttta tacaggttta     6060

ttaatagcaa gtgcaactaa ctggcggcat gccttgcaac acattttgat atattagcca     6120

tgcttccggg taaaggcaag ccccaaactc cttatctttt gcagtctctc tgggatcagt     6180

aaaagaaaaa aaaaataatg tgcttaagaa gtgggactgt aaatatgtat atttaacttt     6240

gtatagccca tgtacctacc ttgtatagaa aaataatttt aaaaatttga atggaagggg     6300

gtaaaggaag tcatgaagtt tttttgcatt tttatttaaa tgaaggaatt ccaaataact     6360

cacctacaga tttttagcac aaaaatagcc attgtaaagt gttaaaattt acgataagta     6420

ttctattggg gaggaaaggt aactctgatc tcagttacag tttttttttc ctttttaatt     6480

tcattatttt gggtttttgg tttttgcagt cctatttatc tgcagtcgta ttaagtccta     6540

ttgctagaat aggttactac aaaaaaggtt atattctgaa agaaaaataa ctgacattat     6600

atataaccaa ttaatttaaa gtattgccat ttaaattaca cactgagagc atgtcctatg     6660

cagacataga tttttctgtt catttatttt tcttcattgc agtggattga tttgataaat     6720

agatgtgttg aattactaca tttgctgtac atattattta ataaacttta ttcagaattg     6780

cgtggcaaaa aaaaaaaaaa aaa                                             6803


<210>  1241
<211>  6065
<212>  DNA
<213>  homo sapiens

<400>  1241
agcagttcag agccccagtt gcagacgact tgtcctgcca ccaccatgag ttctgaatgt       60

gatggtggtt ccaaagctgt gatgaatggc ttggcacctg gcagcaatgg gcaagacaaa      120

gcaactgccg accctttacg cgcacgctct atttctgctg ttaaaatcat tcctgtgaag      180

acagtgaaaa acgcctcagg cctagttctc cctacagaca tggatcctac aaaaatctgc      240

actgggaagg gagcggtgac tctccgggcc tcgtcttcct acagggaaac cccaagcagt      300

agccctgcga gccctcagga aacccggcaa cacgaaagca aaccaggtct ggagccagag      360

ccttcttcag cagatgagtg gaggctttct tccagtgctg atgccaatgg aaatgcccag      420

ccctcttcac tcgctgccaa gggctacaga agtgtgcatc ccaaccttcc ttctgacaag      480

tcccagaggt ggccccacca cagccagcca gcccgcgcct ctggctcctt tgcccccatt      540

agccagacgc caccatcctt ctcaccacca cctccgctgg tccctcctgc cccggaggac      600

ctccgcagag tctcggagcc tgacctcacg ggagctgttt cgagtaccga ttccagtcct      660

ctactaaatg aagtttcttc ttcccttatt ggaactgatt cccaagcctt tccatcagtt      720

agcaagcctt catccgccta tccctccaca acgattgtca atcctactat tgtgctcttg      780

caacacaatc gagaacagca aaaacgactc agtagccttt cagatcctgt ctcagaaaga      840

agagtgggag agcaggactc agcaccaacc caggaaaaac ccacctcacc tggcaaggct      900

attgaaaaaa gagcaaagga tgacagtagg cgggtggtga agagcactca ggacttaagc      960

gatgtttcca tggatgaagt gggcatccca ctccggaaca ctgagagatc aaaagactgg     1020

tacaagacta tgtttaaaca gatccacaaa ctgaacagag atgatgattc agatctgtac     1080

tctcccagat actcattttc tgaagacaca aaatctcccc tttctgtgcc tcgctcaaaa     1140

agtgagatga gctacattga tggtgagaag gtagtcaaga ggtcggccac actacccctc     1200

ccagcccgct cttcctcact gaagtcaagc tcagaaagaa atgactggga acccccagat     1260

aagaaagtag acacaagaaa atatcgtgca gagcccaaga gcatttacga atatcagcct     1320

ggcaagtctt ccgttctgac caacgaaaag atgagtcggg atataagccc agaagagata     1380

gatttaaaga atgaaccttg gtataaattc ttttcggaat tggagtttgg gaaaccgcct     1440

cccaaaaaga tatgggatta tactcctgga gactgctcta tccttcctag agaggataga     1500

aagagctcag ccatcagccc tactccggaa atttcttcag agactcctgg atatatatat     1560

tcttccaact tccatgcagt gaagagggaa tcagacgggg ctcctgggga tctcactagc     1620

ttggagaatg agagacaaat ttataaaagt gtcttggaag gtggtgacat ccctcttcag     1680

ggcctgagtg ggctcaagcg accatccagc tctgcttcca ctaaagattc agaatcgcca     1740

agacatttta taccagctga ttacttggaa tccacggaag aatttattcg aagacgtcat     1800

gatgataaag agaaactttt agcggaccag agacgactta aacgcgagca agaagaggct     1860

gatattgcag ctcgacgcca cacaggcgtc attccgacgc accatcagtt tatcactaat     1920

gagcgctttg gggacctcct caatatagac gatactgcaa aaaggaaatc tgggtcagag     1980

atgagacctg ccagagccaa atttgacttt aaagctcaga cactaaagga gcttcctctg     2040

cagaagggag atattgttta catttataag caaattgatc agaactggta tgaaggagaa     2100

caccacggcc gggtgggaat cttcccacgc acctacatcg agcttcttcc tcctgctgag     2160

aaggcacagc ccaaaaagtt gacaccagtg caggttttgg aatatggaga agctattgct     2220

aagtttaact ttaatggtga tacacaagta gaaatgtcct tcagaaaggg tgagaggatc     2280

acactgctcc ggcaggtaga tgagaactgg tacgaaggga ggatcccggg gacatcccga     2340

caaggcatct tccccatcac ctacgtggat gtgatcaagc gaccactggt gaaaaaccct     2400

gtggattaca tggacctgcc tttctcctcc tccccaagtc gcagtgccac tgcaagccca     2460

cagctttctc atcattcatt gagagcagga ccagatctca cagaatctga aaagagctat     2520

gtgcaacctc aagcccagca gcgaagagtc acccccgaca ggagtcaaac ctcacaagat     2580

ttatttagct atcaagcatt atatagctat ataccacaga atgatgatga gttggaactc     2640

cgcgatggag atatcgttga tgtcatggaa aaatgtgacg atggatggtt tgttggtact     2700

tcaagaagga caaagcagtt tggtactttt ccaggcaact atgtaaaacc tttgtatcta     2760

taagaagact gaaaaccatg gagattattt ttattggagg aggaagcatc attcatgaac     2820

cgatcttttt agttgagtca gtaggaaaat taatacagtg gataaagtaa gaagcaaaag     2880

acagggacag agaagtgttg tgtttaaaac ccaagcctgt ctaaggttac tgtgtattag     2940

acagggccga actagtgtgc tgagcaaaaa gaattgaagc aaattgtatt tacttagccg     3000

cttctgggag ccacttcagc ctttcccctc ccctccactt cttgggtaat ctgacctgaa     3060

gcatagtcca ggagcagagt tagccagaaa tgcctcctgc tgccccagcc ttagagagct     3120

cccatctcaa tcattgagcc tgaaggcttc aagcccaaga atgcaacaag acccccagcc     3180

tacatttctc agctcccctg gagccagctg atcctgtaac gctgctggag gtcagtctga     3240

gctaccaaga ctgtccctag acaaaggtgg agtcccccac actgcccaag accaaatccc     3300

tcactcaacc tgctgaggtg tggatgggga aacagaggca aaactgaggc acctgatgca     3360

ttcagcctgc tgtgcagcag tgccattgac tgccctgatg ttcagagaga aacgcacaca     3420

aggtttgccc atgagaattg gggagcagat ggccaagcag ataggttatg tctgttttct     3480

gagtgatgaa gtcaggaagc cctgtggctc tggaggccac ttgtggttca ttcttttccc     3540

atatccttgg cttttagaaa tggttacctt caggacagtg cagctgcatt tatcagagca     3600

ctattgctaa gttttctttt ctggcttgtg tttttctggg acagtttaga attgggaggc     3660

ctattctcat agaacaccaa aaatgatgtt cagtgattca tttaacatac accaatgtac     3720

tctggctgct ggggggacaa ccataagcaa gacatgccca gggtttgccg tggctccaga     3780

tctactccct gtaggagttc aaggatcaca caaacggtag taaccagggt tgtgaatctg     3840

agtacaccct ggcaaggctt ctcttcagac tgaagcagca attctgccac taccagcagc     3900

aaccaggacg tctgttcttt gtgggggcca gatcagaaga gagaggcccc tgtgacgccc     3960

gggctgcttg gtcacaactc tgtccaattc aaggatgttt atcggcctct cttagatcct     4020

gagtgagaca aatacagaaa tgacccattc cctgcccacc agaaactcag aggtgattgg     4080

ggagactgac acaggaaaat gaacttaatc aagagagact gtgatatgtg ctaagaaggg     4140

tgtgagggag ggagagatga attttccctg gagggatcct agaaagcatt gtcatattgc     4200

catctccatt agctcacttt taaacaacta gggtgctgga agaacctttg tctgagggta     4260

gttcatagct ggaaatactt ggaatatttt ccagagtctc taaactctca tcttccccca     4320

cagatacaca tccaagctca caaataggag tagcaattct aggtggtagg gttgtgtacg     4380

gaacccctgg ctgtctgcat atatctcaga attaccccag gaccattgtc ccaaagtcta     4440

gagtctttac aggtaggcaa aatttgtttt caatgcctgt gcctcagctg ctgtcacaaa     4500

tacccatctt aggatcccat cagcttccca tcccccacca gacagccaca gtaccctcac     4560

tttctcccta ttgttctttc aaatcctgtt ctcaggaaag aaactgccac taattcattc     4620

acactaaggt gtaaatgatt gataatagga atgagttacc tcttcccaca gacatttgtt     4680

tttaagtatg acagagcagg gccttaatcc caagggaaaa ggttatggaa ctggaggggg     4740

tgagctttct gggtagaagg agacttcctg aatttcctta aaacccagta agagtaagac     4800

ctgttgtttt ggaaggtctg ctccaccatc taagagcact gttttttttt ttttgttgtt     4860

gttgttgttt tacggtctct gagggaatat agtaaaaatg catatgcacg tgcaatttgc     4920

acggcagcat ttcaccgatt gtggactgta ttggctaatg tgtttcctgg tctttagatg     4980

caaaccatta ataacactat cttatctcat agttttttca ggggtgcttc ttgattagta     5040

gggaattttg aacacctctt taaatacagc tagaaaataa aaccaatttg taaagccaca     5100

tttgcatatg atgccagcct cacgcatttg tatatctcca gaaattcagg tatgcctcac     5160

caatttgccc gtctttaata aaatcttgtg ttaaaatttg catcacgtcg ccttcctatg     5220

tatgacgaaa caagaaacag agatttccaa ttgctctttt gtcttcagac atttagtaat     5280

ataaagtacc tatttttatg ctgaaatgtt tatacaggtt tattaatagc aagtgcaact     5340

aactggcggc atgccttgca acacattttg atatattagc catgcttccg ggtaaaggca     5400

agccccaaac tccttatctt ttgcagtctc tctgggatca gtaaaagaaa aaaaaaataa     5460

tgtgcttaag aagtgggact gtaaatatgt atatttaact ttgtatagcc catgtaccta     5520

ccttgtatag aaaaataatt ttaaaaattt gaatggaagg gggtaaagga agtcatgaag     5580

tttttttgca tttttattta aatgaaggaa ttccaaataa ctcacctaca gatttttagc     5640

acaaaaatag ccattgtaaa gtgttaaaat ttacgataag tattctattg gggaggaaag     5700

gtaactctga tctcagttac agtttttttt tcctttttaa tttcattatt ttgggttttt     5760

ggtttttgca gtcctattta tctgcagtcg tattaagtcc tattgctaga ataggttact     5820

acaaaaaagg ttatattctg aaagaaaaat aactgacatt atatataacc aattaattta     5880

aagtattgcc atttaaatta cacactgaga gcatgtccta tgcagacata gatttttctg     5940

ttcatttatt tttcttcatt gcagtggatt gatttgataa atagatgtgt tgaattacta     6000

catttgctgt acatattatt taataaactt tattcagaat tgcgtggcaa aaaaaaaaaa     6060

aaaaa                                                                 6065


<210>  1242
<211>  3801
<212>  DNA
<213>  homo sapiens

<400>  1242
agcgggacag acgagcggga ggggcagcgt gcggggagct gggggcgggg cgcggccgca       60

gctccgtttc cggtggctcg tcgcgctcgc tcactccagc tgcagccact ctcgcccgtg      120

gctgcttcct ccatcctggt attttttgga gcttccatcc tggttcttcc aaagtgcccg      180

gacccaaaac aggaaagtgt tgcggagata ggaacatggg agagaaacaa tctgggtaac      240

atgaaagtga tgctggttgc taagggaagg caacttgatt ctgtgggaag ggctgtagct      300

gatccatccg ttgtctagat ttgagtatga gcacagtgga agaggattct gacacagtaa      360

cagtagaaac tgtgaactct gtgactttga ctcaggacac agaagggaat ctcattcttc      420

actgccctca gaatgaagcg gatgaaatag actcagaaga tagtattgaa cctccacata      480

aaaggctttg tttgtcctct gaggatgatc agagtattga tgattctact ccttgcatat      540

cagttgttgc acttccactt tcagaaaatg atcagagctt tgaagtgacc atgactgcaa      600

ccacagaagt agcagatgat gaggttactg aggggactgt gacacagata cagattttgc      660

agaatgagca actagatgaa atatctccct tgggtaacga ggaagtttca gcagttagcc      720

aagcatggtt tacaactaaa gaagataagg attctctgac taataaagga cataaatgga      780

agcaggggat gtggtccaag gaagaaattg atattttgat gaacaatatt gaacgctatc      840

ttaaggcacg cggaataaaa gatgctacag aaatcatctt tgagatgtca aaagacgaaa      900

gaaaagattt ctacaggact atagcatggg gtctgaaccg gcctttgttt gcagtttata      960

gaagagtgct tcgcatgtat gatgacagaa accatgtggg aaaatataca cctgaagaaa     1020

ttgagaagct caaggagctc cggataaagc atggcaatga ctgggcaaca ataggggcgg     1080

cgctaggaag aagtgcatct tctgtcaaag atcggtgccg actgatgaag gatacttgca     1140

acacagggaa gtggacagaa gaagaagaaa agagacttgc agaagtggtt catgagttga     1200

caagcactga gccaggtgac atagtcacac agggtgtgtc ttgggcagct gtggctgaac     1260

gagtcggtac ccgctcagaa aagcaatgtc gttctaaatg gctcaactac ctgaattgga     1320

aacagagtgg gggtactgaa tggaccaagg aagatgaaat caatctcatc ctcaggatag     1380

cagaacttga tgtagctgat gaaaatgaca ttaactggga tctgttagct gagggatgga     1440

gtagtgtccg ttcaccacaa tggctacgaa gtaaatggtg gaccatcaaa aggcaaattg     1500

caaaccataa ggatgtttcg ttccctgtct taataaaagg tcttaaacag ttacatgaga     1560

accaaaaaaa caacccaacg cttttggaga ataaatcagg atctggagtt ccaaacagta     1620

ataccaattc cagtgtgcag catgttcaga taagagttgc ccgcttggaa gataatacag     1680

ccatctcttc tagccccatg gcagcattgc agattccagt ccagatcacc catgtttctt     1740

cagcagactc tcctgctacc gttgactcag aaacaataac actaaacagt ggaacactac     1800

agacatttga gattcttccc tctttccatc tacagcccac tggcactcca ggcacctacc     1860

tacttcaaac aagctcaagc caaggccttc ccctaactct gactgctagt cccacagtaa     1920

ccctgacagc tgctgctcct gcttctcctg aacagattat tgttcatgct ttatccccag     1980

aacatttgtt gaacacaagt gataatgtta cagtgcagtg tcacacacca agagtcatca     2040

ttcagactgt tgccacagag gacatcactt cttccatatc ccaagcagaa ctgacagtcg     2100

atagtgatat tcagtcatct gattttcctg agcctccaga cgccctagaa gcagacactt     2160

tcccagatga aattcatcac cctaagatga ctgtggagcc atcatttaat gatgctcatg     2220

tatccaaatt cagtgaccaa aatagcacag aactgatgaa tagtgttatg gtcagaacag     2280

aagaagaaat ctctgacacc gaccttaaac aagaggaatc accctctgat ttagccagtg     2340

cttatgttac tgagggttta gagtctccca ctatagaaga acaagttgat caaacaattg     2400

atgatgaaac aatacttatc gttccttcac cacatggctt tatccaggca tctgatgtta     2460

tagatactga atctgtcttg cctttgacaa cactaacaga tcccatactc caacatcatc     2520

aggaagaatc aaatatcatt ggatcatcct tgggcagtcc tgtttcagaa gattcaaagg     2580

atgtcgaaga tttggtaaac tgtcattaga ataattctta gaaataggca gttcaagcaa     2640

agaaggcaca ctgttaatta caacctcttc aaagaaatag gagcaacccc caagaggctt     2700

aatttaccaa tttaaatagc cacagtcctt aagccacaca cattgttgct gctatgactt     2760

tttacctcct ttaaacacat catctgaggt tgagttttat gacagtatgt agttgagtgg     2820

aggctgggag ttttaagcat aaatccctgt ttagtgttac atgggaataa ggaatttcat     2880

tcacttcagc cactaagaaa agtttagaat cacgaaagct taactgctgt ggtttaaagt     2940

acagtttctc taaagatcag acatggcact gtctcctctc aagcctggtt gtagttcaga     3000

tgagtctttt caacatggtc ttcaacatgg tctagagctt accagtgatc ttctgatctt     3060

caagaagact aagtttgaga cttgaccagc atacaagtat agagacctag gaggtggtct     3120

tgtggtggta catttggtta acccattgct ggcagtggga gctgatttag gcagggtaaa     3180

caggaaagca ttaaaagtta aaattcacta caggtttttt gttactttta aagggaatat     3240

ggataagcat agtaacaaaa cccaccagaa tctaagcagt tttcaccccc tcagaaacca     3300

ctgtcattag tttacaaagt tagcactttg aagtaaaact aaatgaggaa ggaagtaatg     3360

ttacctatcc ttgataccat gaccatttat tagatgtttt gctatataaa ttaccgagag     3420

aatagtttgt catccactta gtgtgttagc tggtggggta caatataacc tctcatctca     3480

ggctatttta aaaaaacaat atttgcttct ataacaaaag gaaacaaatc taagaatcat     3540

tcctgtacta cagaagggtt aaggcaaagg tagccttttg ggctttttaa tgaatatgac     3600

ccctatagaa aagtcaagaa aaaaaaaccc ttgtataaat tattttattt attattgtaa     3660

ttagatcttc acaaagttgt cttttcactg tgttttgtca acgtgaaatt aaattgtagt     3720

tataagcaaa agttggttgc ctagggaaca attgtatatt cagtttaaca gaaataaaag     3780

aatatttgtc ttaagatgca a                                               3801


<210>  1243
<211>  7025
<212>  DNA
<213>  homo sapiens

<400>  1243
actacctttt ctcttcggtt ggctgtagtt taaattctaa ggtctcctca agaaatgaca       60

ttttcacatt tcttaggcat ctgtggtgcc agaggagcaa acccatcgca cacgccaggt      120

ctgccatggg gccctgggcg gtggggattt tggatgtaac gtgtctaggc cgagcccgcg      180

ccgtgaaagg cctaccctgc cgaaagcccg ggcggcgggc gcccacaagt cagggctcgg      240

tgcggcgccg cagccagctc tgcccgcgag ccgagtccgg gctgctgagg gggagccgcg      300

ctgggggcgg cggcgtcggg gcgggggcgg gagccgggcg gcagctccag cgcccgtggg      360

ggaggagcgg cagcggcggc ggctggagct gctgtggcga ccgacgcgag gcggtggcag      420

aggagaccca cccctgtcca catggacagt cgcaaaggcc tccgctgatg cattcacgcc      480

tgggcggggt gggcggacgg ccgtagcggc ggcggctgca gaacgagcta ggggcctggg      540

ggcgcctgac ggtcgcagag acctcgccgc tccggcgcgg cgggtgcggc cattttacgg      600

cctgggacga agggaggcgt gtttgtgtgc tcgctttcat tctcctttct tgggaaccca      660

cggctggggg aagtttctca ggcagcctgg gtgggcggtg gatggggagt cgtgggccga      720

gaggaaccgg gcccgggaag cgccgtcgtc gtcgtcgccg gtcgcgttcc cccggagagg      780

cctgagaagc tcgggccgcg ggcctcgctg cccgccagcc cgcggacagg cccgggcgcg      840

cctggcctgc ctttgtatag gcccgtctga acgtgggagc gcagcccgcc tgacggctga      900

gcccgaggcc cgcaaccctg cggcgtctac cctcctccgg cgcggcccct catcccggcg      960

agcacggcgg cggtgtgggc catggattaa gaaggaggcg gcgtgggagg aggaagatgg     1020

cggccggcaa gagcggcggt agcgcagggg agattacttt tctggaagct ttggctagat     1080

cagagtctaa gagagatgga ggttttaaaa ataattggag ctttgatcat gaagaagaaa     1140

gtgaaggaga tacagataaa gatgggacaa atctgctcag tgtggatgaa gatgaggatt     1200

ctgaaacctc aaaaggaaaa aagttaaatc gtcgatctga aattgttgct aatagctctg     1260

gtgaattcat cttgaagaca tatgtaagac gaaacaagtc tgaaagtttt aaaactttga     1320

aaggcaaccc aattggactt aacatgttga gcaacaataa gaaattgagt gaaaatacgc     1380

aaaatacgtc attatgttct ggaactgtag ttcatggtag acgttttcat catgctcatg     1440

cacagatacc agtagtaaaa acagcagccc aaaggaaaga atacccacct catgtccaaa     1500

aagttgaaat taatcctgta aggttaagtc ggctccaagg tgttgaacgt ataatgaaga     1560

aaacagaaga gtccgaatca caagtggagc ctgaaattaa gaggaaagta caacagaaac     1620

gacactgtag tacctatcag cctactcctc ctctatctcc tgcttcaaaa aaatgtttaa     1680

cccatttaga ggatttgcaa agaaattgca gacaagctat tactttgaat gagtctactg     1740

gaccattatt aagaacgtca attcatcaga attctggagg acagaagtca caaaacacag     1800

gattaacaac caagaagttt tatggcaaca atgtggaaaa ggttccaatt gatattattg     1860

tgaattgtga tgacagtaaa cacacttatt tacagactaa tggaaaagtc attttacctg     1920

gggcaaaaat acccaaaatc acaaacttga aagaaaggaa aacaagtttg tcagacctaa     1980

atgatccaat cattttgtcc agtgatgatg atgatgacaa cgacagaact aacagaagag     2040

aaagcatatc tcctcagcct gctgattcag catgttcttc ccctgcacca tccactggaa     2100

aagtagaagc agcgctaaat gaaaatactt gcagagcaga gcgtgaacta cgaagcattc     2160

cagaagactc agagttaaat acagttacat tgccaagaaa agcaagaatg aaagaccagt     2220

ttggcaattc tattatcaac acacctctga aacgtcgtaa agtgttttct caagaacctc     2280

cagatgcttt agctttaagc tgccaaagtt cctttgacag tgtcatttta aactgtcgaa     2340

gtatacgagt aggaacactc ttccggctgt taatagagcc tgtaattttt tgtttagatt     2400

ttatcaagat acagctagac gaaccagacc atgatcctgt agagattata ttaaatacct     2460

ctgatctaac taaatgtgaa tggtgtaatg tccgaaaatt acctgtagtg tttcttcaag     2520

caattccagc agtttatcaa aagctgagca tccaactgca aatgaataag gaggataaag     2580

tttggaatga ttgtaaagga gtaaataaat taacaaattt agaagaacaa tatataattt     2640

taatttttca aaatggcctt gatcctccgg caaatatggt atttgaaagt atcattaatg     2700

aaattggtat aaagaataac atctccaatt tttttgcgaa aattcccttt gaagaagcta     2760

atggcagact tgttgcctgt acaagaacct atgaagagag catcaaagga agttgtgggc     2820

aaaaggaaaa caaaattaaa actgtatcat ttgaatctaa aatacaactt agaagcaaac     2880

aagaatttca gttttttgat gaagaagaag aaactggaga aaaccacacc atcttcattg     2940

gcccagtaga aaagttgata gtatatccac cacctccagc taagggaggc atctctgtta     3000

ccaatgagga cctgcactgt ctaaatgaag gagaattttt aaatgatgtt attatagact     3060

tttatttgaa atacttggtg cttgaaaaac tgaagaagga agacgctgac cgaattcata     3120

tattcagttc ttttttctat aaacgcctta atcagagaga gaggagaaat catgaaacaa     3180

ctaatctgtc aatacagcaa aaacggcatg ggagagtaaa aacatggacc cggcacgtag     3240

atatttttga gaaggatttt atttttgtac cccttaatga agctgcacac tggtttttgg     3300

ctgttgtttg tttccccggt ttggaaaaac caaagtatga acctaatcct cattaccatg     3360

aaaatgctgt catacagaaa tgttcaactg tagaggacag ttgtatttct tcttcagcca     3420

gtgaaatgga gagttgttca caaaactctt ctgccaagcc tgtaattaag aagatgctaa     3480

acaaaaaaca ttgcatagct gtaattgatt ccaatcctgg gcaggaagaa agtgaccctc     3540

gttataagag aaacatatgc agtgtaaaat acagtgtgaa aaaaataaat catactgcga     3600

gtgaaaatga agaattcaat aaaggagaat ctacatccca gaaagttgct gataggacta     3660

aaagtgagaa tggcctacag aatgaaagtt taagttccac acatcataca gatggcttaa     3720

gcaaaatcag actaaactat agcgatgaat cacctgaagc tggtaaaatg cttgaagatg     3780

aactcgtcga cttctcagaa gatcaggata accaggatga tagcagtgac gatggattcc     3840

tcgctgatga caactgcagt tcagaaatag gacagtggca tttaaagcct actatctgta     3900

aacaaccttg tatcctactt atggactcac tccgaggccc ttctcggtca aatgttgtca     3960

aaattttaag agagtattta gaagtggaat gggaagttaa aaaaggaagc aaaagaagtt     4020

tttccaaaga tgttatgaag ggctctaatc caaaagtacc acagcaaaac aacttcagtg     4080

actgtggtgt atatgtattg cagtatgtag agagcttttt tgagaatcca attctcagtt     4140

ttgaactacc tatgaatttg gcaaactggt ttcctccacc aagaatgaga acaaaaagag     4200

aagaaatccg aaacataatt ctgaagctac aggaagatca gagcaaagag aaaagaaagc     4260

ataaggacac ttactcaaca gaagcacctt taggcgaagg aacagaacaa tatgtcaata     4320

gtatctcaga ttgaccattt ctgttacttg tcatttctac tttcagaaac taaatgactt     4380

tcaaatttgg gtatagacaa taaagaactg aagtgctcac tactcagtga tttggaaatt     4440

ttgatgcttg tataaatgtc agataattaa tttccaaagg cgtatgtatt aagtaaaagt     4500

ctgtaaatat gttaatgagg ccaatttttc cagcatttat aattattttt ttcacttgtt     4560

aggaagcttt tgttatgtat tttctgttaa tagtacctaa aattgcaact tctaaacaca     4620

aataaaaaga aaatatttat aggaggaaat gattaatttg atattcttta gtgaacttgt     4680

ttaattcctc agtgggtgtg acatatttca tgggaatatt caaatatcta tggtaatatt     4740

ttgacccttt atatttgttc taaaataagt caaaatgtga aaataatatt aaatctaaga     4800

tattttgaac taagcatctt tatatgcttg tgtaacagga acaaagtaac agcctttcaa     4860

ttcatatact gccttgtgtt cagtgaaccc aagaaatgta ataaatattt gtaattttac     4920

acaaatattt aagaggaaag agtattaaga gcaattcaaa aaaagtaacc ttatactact     4980

aaaaaaaaaa ttcttgcata tattatcatc aaatgcattt ttgaagacat caaagactca     5040

ggttaaaact attttggtaa gtgcagcttg aatttcaaat atcccgtgtt acctttctct     5100

attacagctt aaagtatgct acaatctgtg tcatatagtt aattgataag catttttaat     5160

ctgtgtaaac acaggaattt aaataggaat ttactatttt tttataaagc ttttgctatt     5220

ttttcattgc tcattttgtt cttattattt tgataaagta tcagactttt tgcttgagtt     5280

cttcagtgta aattattttt tacatgtaaa agtactgtat tcaaccagtt gcataataca     5340

gcaaaaatct ttgaattccc ctttaaaata actaaaattt gatggtttcc atgacagatt     5400

tatagcacat atagggatct tgcatgtatc tgcagaaact tcattatttt tcaaatgaaa     5460

tggtgtatac ttctttcaaa tgaactttga gacttgaaac atattttagt cattttttgt     5520

taaatattga atttttaaat acacatatat caaaaatagt tgagaataaa aagaaagcct     5580

aatcatcagc aattatttta tttttaattt ggccatctct gacattgcag tcaatatctt     5640

agggtatttt cttgaattta ataaagtccc atgggtgggt tcagggtgaa tgggagtatt     5700

aacaacaacc aaaaaatatc tattgagaca cagtagagtc tcagtaagag aaatattaaa     5760

atgtaagaaa ggtcaccatt agtgatatca actgtagttt gttactttga actatatttc     5820

tgattaactc tttatagtaa taacttagag ctgttagctc agatatctta attagctcat     5880

atgaaaaaca agtttaattt tattatttac tgaacatggc aaaatgcttt tcaatctata     5940

ataaaactgg gataaaaaat tgaagttgtt ttttttaaaa cctaatagca ataagcaaaa     6000

ttggcataca taattttttt aatgaactat attttgtcag aatctgaagg tactgaaaaa     6060

ctattctaaa atgcctactt gtttttgcat taatttgtaa tgcttacatt ttgcaccctt     6120

agataatgtt tgataagata aaaatataat ttatcccttg taccaactca agtcaatcag     6180

attttaacat gaaaaatata gattaatgta tgtcagcttt ctagaggtag aatactcagc     6240

tatttgatgg catttttccc accccatgtg aaattttatt tttggaagtt atgctagtga     6300

cattgcaata tatattgaaa tcttcggagg ctgccaggtt gagcttcaaa actagacttg     6360

agaatctttc gtgtatatgc acattcactt gataattgtg tattctatgt agtttaaagt     6420

gggatcaagc cttttaaaat gtgttattag tacttagaag ttgtaaaaca gaacttatag     6480

aggtttgtta ctagacactg aaactgcatg acaagtatct ggtgtcttaa ctaattagat     6540

agatctgttg tattggtttt cttgttggat agaataacag ttaatcattt ttagaagagt     6600

tttagattac ttgccataaa atttgtatgt ctcagctctt gttggtttag gagcagaagt     6660

ggtgtttagt cccttcccgt taatgttgct gtgctacttc agacagctga aaacttaatg     6720

gtattatttc aagttcacat aaccctaaaa aaggttttct ttgtgtagta acttgtgctt     6780

aaacttttag tcaattaaat gtaggaggtt ttatttgaaa acataaaatg attctctaaa     6840

ttacatcttg ttttaagcca ccaaaatgaa tgcagtaatt tttctttaaa aaaatgatct     6900

ctgaaaactg tgagacaatg taaaaagaat aagttttaat tcccccaaaa tcaaaaattg     6960

tacttaaaat ctcagacaat tcactgaaca ggaataataa agaacatatt ttaatatata     7020

atatg                                                                 7025


<210>  1244
<211>  4805
<212>  DNA
<213>  homo sapiens

<400>  1244
gcctagggag gaggagcgag aatcagcctg gttcagtgac tgagacaaac tggaggtgaa       60

aggagctggt actgtccact gtgctgtcgg tgctgaacct gagacgcgag cggaccagtt      120

gctccagcac ctgaaggcaa cgccctcttg caccctctgt gccctgtggg acccgcttca      180

ccaacaggac ccatatcaac ttgacaaagg agtgtggtat cggacgtggg agagagtcct      240

ctgtttgcca cctgggcgct cattcaggcg tgactttgga gatttctata gttttagacc      300

aaactatttt tttttcccca gctaagacga tcttttgaga gttttttttt tttattgtga      360

tttatatttc cacagcgttt aggaatcttt ctgggggact tttgtgactg ttaaaataag      420

gtgaaaagca ataaggatgt ttaagtgctg gtcagttgtc ttggttctcg gattcatttt      480

tctggagtcg gaaggaaggc caaccaaaga aggaggatat ggccttaaat cctatcagcc      540

tctaatgaga ttgcgacata aggaaaaaaa tcaagaaagt tcaagagtca aaggatttat      600

gattcaggat ggcccttttg gatcttgtga aaataagtac tgtggtttgg gaagacactg      660

tgttaccagc agagagacag ggcaagcaga atgtgcctgt atggaccttt gcaaacgtca      720

ctacaaacct gtgtgtggat ctgacggaga attctatgaa aaccactgtg aagtgcacag      780

agctgcttgc ctgaaaaaac aaaagattac cattgttcac aatgaagact gcttctttaa      840

aggagataag tgcaagacta ctgaatacag caagatgaaa aatatgctat tagatttaca      900

aaatcaaaaa tatattatgc aagaaaatga aaatcctaat ggcgacgaca tatctcggaa      960

gaagctattg gtggatcaaa tgtttaaata ttttgatgca gacagtaatg gacttgtaga     1020

tattaatgaa ctaactcagg tgataaaaca ggaagaactt ggcaaggatc tctttgattg     1080

tactttgtat gttctattga aatatgatga ttttaatgct gacaagcacc tggctcttga     1140

agaattttat agagcattcc aagtgatcca gttgagtctg ccagaagatc agaaactaag     1200

catcactgca gcaactgtgg gacaaagtgc tgttctgagc tgtgccattc aaggaaccct     1260

gagacctccc attatctgga aaaggaacaa tattattcta aataatttag atttggaaga     1320

catcaatgac tttggagatg atgggtcctt gtatattact aaggttacca caactcacgt     1380

tggcaattac acctgctatg cagatggcta tgaacaagtc tatcagactc acatcttcca     1440

agtgaatgtt cctccagtca tccgggtgta tccagagagt caggctagag agcctggggt     1500

aactgccagt cttaggtgcc atgcagaggg cataccaaag cctcagcttg gctggttgaa     1560

gaatggaatt gatattacac caaagctttc caaacaactc acgcttcaag caaatggcag     1620

tgaggttcac ataagcaatg tgcgctatga agatactgga gcatacactt gtatcgcaaa     1680

gaatgaagca ggagtggatg aagacatctc ttctcttttt gtggaagact ctgctagaaa     1740

gacccgtctg ggaattggga acatgttcta tgttttttat gaagatggaa tcaaagtgat     1800

acaacccata gaatgtgaat ttcagaggca cattaagcct agtgaaaagc tccttggatt     1860

tcaggatgaa gtctgtccca aagctgaggg agatgaagtt cagaggtgtg tgtgggcatc     1920

agctgttaat gtcaaagaca agttcattta tgttgcacag ccaactttgg acagagtcct     1980

tattgttgat gtgcagtccc aaaaagttgt tcaggcagtg agcacagacc ctgtcccagt     2040

taaattacac tatgacaaat cacatgatca ggtctgggtg ctaagctggg gtaccttgga     2100

gaagacatca ccaacactac aggtaattac cctggccagt gggaatgtgc ctcaccacac     2160

gatccacacc caaccagtgg gaaagcaatt tgacagagtg gatgattttt tcattcccac     2220

cacaacactc attatcaccc atatgaggtt tggatttatt cttcataaag atgaagctgc     2280

actacaaaaa attgatcttg aaaccatgtc atacatcaag acaattaact tgaaggacta     2340

taagtgcgtt cctcagtcat tggcatatac acacttggga ggctactact tcattggctg     2400

caaacctgac agcaccggag cagtttcccc acaggtcatg gtggacggtg taactgactc     2460

agtcattggg ttcaatagtg atgtgacggg cactccatat gtctctccag atggccacta     2520

ccttgtcagc attaatgatg tgaaaggtct tgtaagggtt cagtacatta ccatcagagg     2580

agaaatacag gaggcttttg atatttacac aaatctgcac atatctgatc tggcatttca     2640

accatccttt actgaagccc accaatataa catctacggt agttcaagca cacaaactga     2700

tgtgctcttt gtggagctct cttctgggaa ggtcaagatg ataaagagtc tcaaggaacc     2760

actcaaggca gaagaatggc cttggaaccg gaaaaacagg caaatccagg acagtggctt     2820

gtttggtcaa tacctgatga caccttccaa ggactctctc ttcatcctag atggacgact     2880

caataaatta aactgtgaga tcactgaagt tgaaaaagga aatacagtca tttgggttgg     2940

agatgcctaa aaaccctacg atacaattat tgaatgaagc gttttacaat acattgcact     3000

taatccattg tttaaattta caacttaact ttccaagttt atatcctagt caaacaaaat     3060

ttacttggtt ggtccaaata aaataaattg tttttgacta agtgactaag acatacacaa     3120

ttaattatat tggttaatta gaaatactca gcacaatatt taatgagaaa tcacatcagt     3180

cacaagaatc aaatatgtaa attatgcttt aaacaataaa gtaggattta aatcatttaa     3240

aaaactaaac tgcagggaat ttcagatgac ataaagcatt atttcatttt gagggtagtt     3300

tatttttttt ctctgtcctt ttggtatgat taaacaagaa ataaaaggtg ttgtggaaac     3360

ttaaaattct taattcaaaa tattcggtcc tgtccactgt ttataatatt ttgtgccttg     3420

aagggaatgt cacaggagga aaaggaagac taaagcctgc atactaaatg ctctcataac     3480

tataaatctc ttgttgttaa aaaacatctc ttgcaccaaa tcctgtcttc agtcttttgt     3540

ttaaccctca atgaactacc aattgaaggc ataagttggt cttaggttgt atacaggtgt     3600

caaactccac ttgacattta ctgtataatc tgcagcatgc tatagaaagt ggggaggaag     3660

ggaggaaaaa taattacagt caaaatattt gcaatctatc tactcatttt gctttcaatc     3720

actagagtgc attatgtttt taatgcaagt ttgtctggga tgtcaactgc ctacagatgt     3780

ttattactag cagaatagat tatttattaa tagattgttt cttttcatat agtccaatgt     3840

ttcatcatca ggaactttcg gttttaaaaa agaaacatta cttttgtctg ctaaagtaaa     3900

ccatatatag ggaaattaac acctaggaaa agaaaactgg caagagaatt gatgaggtat     3960

tagtggctta gaagaattag taatataagt tgggaataaa ggggtagccc gacagtggta     4020

agtaaaaatg tagtactcca ttgtttttgc tatttaaata taatgtatca aaaaccttta     4080

ttctaaaatt tccacaaatg attcctttta tccatcttct tgtaatccta aaagcatctt     4140

ctcactatgt gctgtagttt gaaacctaac gaatcctcct acttgagaca ctgtagaaaa     4200

gtaaaaattg ttgcttctgt tttgttttaa gaggaaatga gaaggccagc agaagtagat     4260

taaaactaga gagctggttt attaaaataa gcagataatt atccaggctt aaagtaatag     4320

cttacatgtt ttgaaaatcc ttgtacttat ttttgttttt attgttgcaa aaaaatgtta     4380

atgggctgtt gaaatgacct ccatttactt aaggtaatcc aataaggtct tttttaaata     4440

tacaaatttt actcaagttt aaattgtata aaactgctta gaaacctgaa attttatagt     4500

gtgtaatatc ttatgtgtat atagcatcct gagctgtgtg atacagtaga tttcttctta     4560

gcagaaacat gcgaggtaga tttaataaac aacaaaaatc agcttatgtt tctacttatt     4620

gaatctgctt tactttttag caattttctt ccttgtgaac atgaaccata taaagtgtct     4680

gtgacttaat gatttcatgt aagtctgtcg catacatcct tcttttgtag cttacaccat     4740

gtggatgctc tgtctgtaga cactgcttga taaaaggaga ataaacctct tacattttaa     4800

ccctt                                                                 4805


<210>  1245
<211>  4835
<212>  DNA
<213>  homo sapiens

<400>  1245
gcctagggag gaggagcgag aatcagcctg gttcagtgac tgagacaaac tggaggtgaa       60

aggagctggt actgtccact gtgctgtcgg tgctgaacct gagacgcgag cggaccagtt      120

gctccagcac ctgaaggcaa cgccctcttg caccctctgt gccctgtggg acccgcttca      180

ccaacaggac ccatatcaac ttgacaaagg agtgtggtat cggacgtggg agagagtcct      240

ctgtttgcca cctgggcgct cattcaggcg tgactttgga gatttctata gttttagacc      300

aaactatttt tttttcccca gctaagacga tcttttgaga gttttttttt tttattgtga      360

tttatatttc cacagcgttt aggaatcttt ctgggggact tttgtgactg ttaaaataag      420

gtgaaaagca ataaggatgt ttaagtgctg gtcagttgtc ttggttctcg gattcatttt      480

tctggagtcg gaaggaaggc caaccaaaga aggaggatat ggccttaaat cctatcagcc      540

tctaatgaga ttgcgacata agcaggaaaa aaatcaagaa agttcaagag tcaaaggatt      600

tatgattcag gatggccctt ttggatcttg tgaaaataag tactgtggtt tgggaagaca      660

ctgtgttacc agcagagaga cagggcaagc agaatgtgcc tgtatggacc tttgcaaacg      720

tcactacaaa cctgtgtgtg gatctgacgg agaattctat gaaaaccact gtgaagtgca      780

cagagctgct tgcctgaaaa aacaaaagat taccattgtt cacaatgaag actgcttctt      840

taaaggagat aagtgcaaga ctactgaata cagcaagatg aaaaatatgc tattagattt      900

acaaaatcaa aaatatatta tgcaagaaaa tgaaaatcct aatggcgacg acatatctcg      960

gaagaagcta ttggtggatc aaatgtttaa atattttgat gcagacagta atggacttgt     1020

agatattaat gaactaactc aggtgataaa acaggaagaa cttggcaagg atctctttga     1080

ttgtactttg tatgttctat tgaaatatga tgattttaat gctgacaagc acctggctct     1140

tgaagaattt tatagagcat tccaagtgat ccagttgagt ctgccagaag atcagaaact     1200

aagcatcact gcagcaactg tgggacaaag tgctgttctg agctgtgcca ttcaaggaac     1260

cctgagacct cccattatct ggaaaaggaa caatattatt ctaaataatt tagatttgga     1320

agacatcaat gactttggag atgatgggtc cttgtatatt actaaggtta ccacaactca     1380

cgttggcaat tacacctgct atgcagatgg ctatgaacaa gtctatcaga ctcacatctt     1440

ccaagtgaat gttcctccag tcatccgggt gtatccagag agtcaggcta gagagcctgg     1500

ggtaactgcc agtcttaggt gccatgcaga gggcatacca aagcctcagc ttggctggtt     1560

gaagaatgga attgatatta caccaaagct ttccaaacaa ctcacgcttc aagcaaatgg     1620

cagtgaggtt cacataagca atgtgcgcta tgaagatact ggagcataca cttgtatcgc     1680

aaagaatgaa gcaggagtgg atgaagacat ctcttctctt tttgtggaag actctgctag     1740

aaagacccta gctaacatat tatggagaga agaaggtctg ggaattggga acatgttcta     1800

tgttttttat gaagatggaa tcaaagtgat acaacccata gaatgtgaat ttcagaggca     1860

cattaagcct agtgaaaagc tccttggatt tcaggatgaa gtctgtccca aagctgaggg     1920

agatgaagtt cagaggtgtg tgtgggcatc agctgttaat gtcaaagaca agttcattta     1980

tgttgcacag ccaactttgg acagagtcct tattgttgat gtgcagtccc aaaaagttgt     2040

tcaggcagtg agcacagacc ctgtcccagt taaattacac tatgacaaat cacatgatca     2100

ggtctgggtg ctaagctggg gtaccttgga gaagacatca ccaacactac aggtaattac     2160

cctggccagt gggaatgtgc ctcaccacac gatccacacc caaccagtgg gaaagcaatt     2220

tgacagagtg gatgattttt tcattcccac cacaacactc attatcaccc atatgaggtt     2280

tggatttatt cttcataaag atgaagctgc actacaaaaa attgatcttg aaaccatgtc     2340

atacatcaag acaattaact tgaaggacta taagtgcgtt cctcagtcat tggcatatac     2400

acacttggga ggctactact tcattggctg caaacctgac agcaccggag cagtttcccc     2460

acaggtcatg gtggacggtg taactgactc agtcattggg ttcaatagtg atgtgacggg     2520

cactccatat gtctctccag atggccacta ccttgtcagc attaatgatg tgaaaggtct     2580

tgtaagggtt cagtacatta ccatcagagg agaaatacag gaggcttttg atatttacac     2640

aaatctgcac atatctgatc tggcatttca accatccttt actgaagccc accaatataa     2700

catctacggt agttcaagca cacaaactga tgtgctcttt gtggagctct cttctgggaa     2760

ggtcaagatg ataaagagtc tcaaggaacc actcaaggca gaagaatggc cttggaaccg     2820

gaaaaacagg caaatccagg acagtggctt gtttggtcaa tacctgatga caccttccaa     2880

ggactctctc ttcatcctag atggacgact caataaatta aactgtgaga tcactgaagt     2940

tgaaaaagga aatacagtca tttgggttgg agatgcctaa aaaccctacg atacaattat     3000

tgaatgaagc gttttacaat acattgcact taatccattg tttaaattta caacttaact     3060

ttccaagttt atatcctagt caaacaaaat ttacttggtt ggtccaaata aaataaattg     3120

tttttgacta agtgactaag acatacacaa ttaattatat tggttaatta gaaatactca     3180

gcacaatatt taatgagaaa tcacatcagt cacaagaatc aaatatgtaa attatgcttt     3240

aaacaataaa gtaggattta aatcatttaa aaaactaaac tgcagggaat ttcagatgac     3300

ataaagcatt atttcatttt gagggtagtt tatttttttt ctctgtcctt ttggtatgat     3360

taaacaagaa ataaaaggtg ttgtggaaac ttaaaattct taattcaaaa tattcggtcc     3420

tgtccactgt ttataatatt ttgtgccttg aagggaatgt cacaggagga aaaggaagac     3480

taaagcctgc atactaaatg ctctcataac tataaatctc ttgttgttaa aaaacatctc     3540

ttgcaccaaa tcctgtcttc agtcttttgt ttaaccctca atgaactacc aattgaaggc     3600

ataagttggt cttaggttgt atacaggtgt caaactccac ttgacattta ctgtataatc     3660

tgcagcatgc tatagaaagt ggggaggaag ggaggaaaaa taattacagt caaaatattt     3720

gcaatctatc tactcatttt gctttcaatc actagagtgc attatgtttt taatgcaagt     3780

ttgtctggga tgtcaactgc ctacagatgt ttattactag cagaatagat tatttattaa     3840

tagattgttt cttttcatat agtccaatgt ttcatcatca ggaactttcg gttttaaaaa     3900

agaaacatta cttttgtctg ctaaagtaaa ccatatatag ggaaattaac acctaggaaa     3960

agaaaactgg caagagaatt gatgaggtat tagtggctta gaagaattag taatataagt     4020

tgggaataaa ggggtagccc gacagtggta agtaaaaatg tagtactcca ttgtttttgc     4080

tatttaaata taatgtatca aaaaccttta ttctaaaatt tccacaaatg attcctttta     4140

tccatcttct tgtaatccta aaagcatctt ctcactatgt gctgtagttt gaaacctaac     4200

gaatcctcct acttgagaca ctgtagaaaa gtaaaaattg ttgcttctgt tttgttttaa     4260

gaggaaatga gaaggccagc agaagtagat taaaactaga gagctggttt attaaaataa     4320

gcagataatt atccaggctt aaagtaatag cttacatgtt ttgaaaatcc ttgtacttat     4380

ttttgttttt attgttgcaa aaaaatgtta atgggctgtt gaaatgacct ccatttactt     4440

aaggtaatcc aataaggtct tttttaaata tacaaatttt actcaagttt aaattgtata     4500

aaactgctta gaaacctgaa attttatagt gtgtaatatc ttatgtgtat atagcatcct     4560

gagctgtgtg atacagtaga tttcttctta gcagaaacat gcgaggtaga tttaataaac     4620

aacaaaaatc agcttatgtt tctacttatt gaatctgctt tactttttag caattttctt     4680

ccttgtgaac atgaaccata taaagtgtct gtgacttaat gatttcatgt aagtctgtcg     4740

catacatcct tcttttgtag cttacaccat gtggatgctc tgtctgtaga cactgcttga     4800

taaaaggaga ataaacctct tacattttaa ccctt                                4835


<210>  1246
<211>  1245
<212>  DNA
<213>  homo sapiens

<400>  1246
ataagagacc acaagcgacc cgcagggcca gacgttcttc gccgagagtc gtcggggttt       60

cctgcttcaa cagtgcttgg acggaacccg gcgctcgttc cccaccccgg ccggccgccc      120

atagccagcc ctccgtcacc tcttcaccgc accctcggac tgccccaagg cccccgccgc      180

cgctccagcg ccgcgcagcc accgccgccg ccgccgcctc tccttagtcg ccgccatgac      240

gaccgcgtcc acctcgcagg tgcgccagaa ctaccaccag gactcagagg ccgccatcaa      300

ccgccagatc aacctggagc tctacgcctc ctacgtttac ctgtccatgt cttactactt      360

tgaccgcgat gatgtggctt tgaagaactt tgccaaatac tttcttcacc aatctcatga      420

ggagagggaa catgctgaga aactgatgaa gctgcagaac caacgaggtg gccgaatctt      480

ccttcaggat atcaagaaac cagactgtga tgactgggag agcgggctga atgcaatgga      540

gtgtgcatta catttggaaa aaaatgtgaa tcagtcacta ctggaactgc acaaactggc      600

cactgacaaa aatgaccccc atttgtgtga cttcattgag acacattacc tgaatgagca      660

ggtgaaagcc atcaaagaat tgggtgacca cgtgaccaac ttgcgcaaga tgggagcgcc      720

cgaatctggc ttggcggaat atctctttga caagcacacc ctgggagaca gtgataatga      780

aagctaagcc tcgggctaat ttccccatag ccgtggggtg acttccctgg tcaccaaggc      840

agtgcatgca tgttggggtt tcctttacct tttctataag ttgtaccaaa acatccactt      900

aagttctttg atttgtacca ttccttcaaa taaagaaatt tggtacccag gtgttgtctt      960

tgaggtcttg ggatgaatca gaaatctatc caggctatct tccagattcc ttaagtgccg     1020

ttgttcagtt ctaatcacac taatcaaaaa gaaacgagta tttgtattta ttaaactcat     1080

tagtttgggc agtatactaa ggtgtggctg tcttggattc agatagaact aagggttccc     1140

gactctgaat ccagagtctg agttaaatgt ttccaatggt tcagtctagc tttcacagtt     1200

tttatgaata aaaggcatta aaggctgaaa aaaaaaaaaa aaaaa                     1245


<210>  1247
<211>  5242
<212>  DNA
<213>  homo sapiens

<400>  1247
agctttcaaa aatagcatag ttgatgaaac tggaaattta ggtgcgggct cttttaagaa       60

atcatttgtc ttcagtctta agaatagact gacaacagat actgctacca gagggctctc      120

aactatttct taagaccccc taggaaatat cagaagaaaa gcctccttct caataaagca      180

taagtaggac atctcgtttt cagtgaatca gacacttgga ttggacttaa tcttaaacct      240

ctggagttca agacctttta aaaagggcta aataaacaat ctctacatgt aaaaggccac      300

tgactcctac ttcctctgta tagagcaact gttgaactca gctgcctgta gggcgtgatt      360

ctcagtcacc agactcagca aaaggtttta gaagcgttcg accaaaccta caagataaaa      420

gatcaccaac tcaggcaccc cctccaccag aaagaaaaga gagctttcat agctctttga      480

taaccagtca cacaaagggt gtcattttag accagttagt aactaacaca caaattccct      540

ccagtacaga gtactttgct aacaaaaaac ctcttcaggg aactatgtat tccaatgaag      600

attcgagaca gacaattgta tattctgaag aatctaacac aaccatgtca tatacacaaa      660

aaatcactaa tccactacca gcagcttcca gcacggatcc tgcaccattc gctaacatca      720

acaccccagt tctacaagag gactacaggc aagattctca aactcggagg atttctacct      780

tgaaactaac ccataaccag gatctaggaa gtagcagccc cattagtact ccacagttct      840

ccaaatctgt cgaagtaccg tcatttctca aaaggccccg ctcactgacc cctaatccag      900

tgcctgagac acacacagca tctctttcca ttcagatagc tcccctttca ggacaggatc      960

ttgaaagcca caaacagcta cctgagcttt ctccagagac tgcaaagata cctcttcagc     1020

aagagagaca aaaatctgca gttgcagcgg cctctcagtc ctcagactgc agagtgagcc     1080

agataacagt gaatggaaac tcaggaggtg ccgtgagtcc catgagttac tatcagaggc     1140

cgttttcccc ctcggcatat tctctcccag cctcactcaa ctccagcatt gtcatgcagc     1200

acggcacatc cctcgattcc acagacacat atccccagca tgcgcagtct ctggatggca     1260

ccaccagcag ctctatcccc ctgtaccgat cctcagagga agagaagaga gtgacagtca     1320

tcaaagcccc gcattaccca gggatcgggc ccgtggatga atccggaatc cccacagcaa     1380

ttagaacgac agtcgaccgg cccaaggact ggtacaagac gatgtttaag caaattcaca     1440

tggtgcacaa gccggatgat gacacagaca tgtataatac tccttataca tacaatgcag     1500

gtctgtacaa cccaccctac agtgctcagt cacaccctgc tgcaaagacc caaacctaca     1560

gacctctttc caaaagccac tccgacaaca gccccaatgc ctttaaggat gcgtcctccc     1620

cagtgcctcc cccacatgtt ccacctccag tcccgccgct tcgaccaaga gatcggtctt     1680

caacagaaaa gcatgactgg gatcctccag acagaaaagt ggacacaaga aaatttcggt     1740

ctgagccaag gagtattttt gaatatgaac ctggcaagtc atcaattctt cagcatgaaa     1800

gaccaccccc tctcccaaca actccgacac ctgttccaag ggaacctggc cggaagcctc     1860

tttctagctc ccgactcgga gaagtcactg gtagcccctc ccctccgccc cggagtggcg     1920

cccccacacc aagctcgcgc gccccggctc tgtctcccac ccggcctcct aaaaagcctc     1980

tggactatgt tcaagatcat tcttctggtg ttttcaatga ggcctccttg tatcagtcct     2040

ctatagacag aagcctggaa agacccatga gttctgcaag catggccagt gacttcagga     2100

agcggaggaa gagcgagcct gcagtgggtc caccacgggg cttgggagat caaagtgcga     2160

gcaggactag cccaggccga gtggacctcc caggatcaag caccactctt acaaagtctt     2220

tcactagctc ttctccttct tccccatcaa gagcaaaaga ccgtgagtcc cctagaagtt     2280

actcatccac tttgactgac atggggagaa gtgcaccaag ggaaagaaga ggaactccag     2340

aaaaagagaa attgcctgca aaagctgttt atgattttaa ggctcagaca tctaaggagt     2400

tgtcatttaa gaaaggagat actgtctaca tcctcaggaa aattgatcaa aattggtatg     2460

agggagaaca ccacgggaga gtgggcatct tcccgatctc atacgtagag aaactcacac     2520

ctcctgagaa agcacagcct gcaagaccac ctccgccagc ccagcccgga gaaatcggag     2580

aagctatagc caaatacaac ttcaacgcag acacaaatgt ggagctgtca ctgagaaagg     2640

gagatagagt tattcttctt aaaagagttg atcaaaactg gtatgaaggt aaaatcccag     2700

gaaccaacag acaaggcatc ttccctgttt cctatgtgga ggtcgtcaag aagaacacaa     2760

aaggtgctga ggactaccct gaccctccaa taccccacag ctattctagt gataggattc     2820

acagcttgag ctcaaataag ccacagcgtc ctgtgtttac tcatgaaaat attcaaggtg     2880

ggggggaacc gtttcaggct ctgtataact atactcccag gaatgaagat gagctggagc     2940

tcagagaaag tgatgtcatt gatgtcatgg aaaagtgtga tgacggctgg tttgtgggga     3000

cctcaagaag aaccaaattc tttggtactt tccccggaaa ctacgtcaag aggctgtgaa     3060

ttgcgctccc tccttctgta gaggccgcct gccagccatg cacctgcgtc aacgcgcctg     3120

aaacaccccg cgggcctccc gttgtcatgc cttacggttt ccaatgcgcc gtcaccatct     3180

ccacctgcca ccaaaccacc agcagagtag ccgccgctgc tgtgagcctg gggacgacat     3240

ggcaggctgg tccccctccg tgaaagtgtg gattcctact tcctgctcta agctttgaca     3300

cgtcaaaatg tgggatcaga aagaaaaaaa tcatgatatt taaaaatggt caaatatttg     3360

aggcaaaaaa aaaaaaaaaa agtgtctcca ggaggctgtc cagcctcgtg gctccatttc     3420

aacatctccc cccaggcgat gttctccccc aagacgacca gaaaattgtt tattggggaa     3480

tgctgtggtt tgcattttca tattcttcgc ttggcagtgt gtattctttt cacaagtttg     3540

cctagtgtct tggtttacac aatatgacaa ctgtaactgt actttagcta ttgtttgcct     3600

gcacatacat gttgtaatat gcacagtgat tacaaccttt aaagcaagag gaggcgagtt     3660

aatttggatg agtgtgattt tgctgattga atgtgagttt tcaaatagga gtctttttct     3720

gcaatttgtt tgcatttttt agaagtgcaa acagtaagta aataaaagcc ttcggtaata     3780

atcatgacaa tacaagaggc tgagctaggc tacaggggaa aactattgtg ttgtaaagtt     3840

gcatcgctat tttatattaa aatgtaatga tcagcatcat gaacaatgag ctcttagtgt     3900

tttatttatc tgaaaaaatg taagtaaaag cagtgttagt gagaggtgca aagaattatt     3960

ctaacagaca cctgaaagta tctgtaagca atactagtag gtaagatttc actgtgtgta     4020

cacatacaca tttgagattg tatgagaaca tataatccat atgatatgtt gtacatttta     4080

tggaaatgta atagaatctc acacattatt ttatagaaat agagtacaga agcatcacaa     4140

gtattaaagt tggttttagc aaggattagg attactacaa ttatttttac tataataatt     4200

atttttcttc tatggaactc agaatcctgg ctacatttga ggacaggaat atgttgagcc     4260

tgattttcct ggtgtgtgta aaatatttcc taggaataaa ttaggcactt tttagaagca     4320

atgttaaatc attcaggttt tattttctgc cctgaagcag aaatttaaaa aatgatattg     4380

ggacctggaa ggtttaatat ggttcacagt gcctgaatta cacctgctcc gaaaactagc     4440

tttgtatttc ttatgacttt gcataagaac tgttcatctt tggatcttga gcaccttaca     4500

gataaaactt tttatggcat ctctttcatg gacagtgata ttgatctttt cacaatgtac     4560

gtagcctcta gaattttgta catatgtttg ctcttttttt gtacagacta gttgttgaga     4620

aaacaggggc gtttcctaat ttggtcttta tcctgcgaca acactttcag cagactagcc     4680

tctccttatc tcacagatca caagcacccc tagatagtgt gattctgtca gatagcattt     4740

atgcaaaaat ctatgaagtt aaaagatcgt agaagccaaa tgaaatgtac atatctactg     4800

actgatgaca agggaatttc attaggaaga aggtaaagaa acatcgttga gtagcctacc     4860

ttgatttctg tcaagttcat aaccagcttc atattttaaa ggcttcaggt ttgaaattaa     4920

gtcaactgca tgcagctttg ctgataaatg aataattctc tttgatgcca tttatgagaa     4980

aagacttcaa tatctgttgc ctgtcatatt taagaaaaat tactgtttct actctctgta     5040

tctgatttta aaagaaaaaa ctattcatac ctggcttcca ggtaattgac tttgaattct     5100

tacaagcaaa ggtcattgtg tttttcttga atagacatct aataaatttt gcttggaagt     5160

atacttcagt ttttcttctt gacatttatc tttataaaaa ttgtgtattt tattccaact     5220

tgttaaacta agagaaaatg ca                                              5242


<210>  1248
<211>  3178
<212>  DNA
<213>  homo sapiens

<400>  1248
agccccgccc ccgcttgcgc gaggcctagg gctgcaggcg cggagccgcg agccccagcc       60

aatgagcgcc ggcgggccgg ttgcccaggc gaccagtgcg cggctccgcc ccccgcggcg      120

aggctcccgc gcgcggctga gtgcggactg gagtgggaac ccgggtcccc gcgcttagag      180

aacacgcgat gaccacgtgg agcctccggc ggaggccggc ccgcacgctg ggactcctgc      240

tgctggtcgt cttgggcttc ctggtgctcc gcaggctgga ctggagcacc ctggtccctc      300

tgcggctccg ccatcgacag ctggggctgc aggccaaggg ctggaacttc atgctggagg      360

attccacctt ctggatcttc gggggctcca tccactattt ccgtgtgccc agggagtact      420

ggagggaccg cctgctgaag atgaaggcct gtggcttgaa caccctcacc acctatgttc      480

cgtggaacct gcatgagcca gaaagaggca aatttgactt ctctgggaac ctggacctgg      540

aggccttcgt cctgatggcc gcagagatcg ggctgtgggt gattctgcgt ccaggcccct      600

acatctgcag tgagatggac ctcgggggct tgcccagctg gctactccaa gaccctggca      660

tgaggctgag gacaacttac aagggcttca ccgaagcagt ggacctttat tttgaccacc      720

tgatgtccag ggtggtgcca ctccagtaca agcgtggggg acctatcatt gccgtgcagg      780

tggagaatga atatggttcc tataataaag accccgcata catgccctac gtcaagaagg      840

cactggagga ccgtggcatt gtggaactgc tcctgacttc agacaacaag gatgggctga      900

gcaaggggat tgtccaggga gtcttggcca ccatcaactt gcagtcaaca cacgagctgc      960

agctactgac cacctttctc ttcaacgtcc aggggactca gcccaagatg gtgatggagt     1020

actggacggg gtggtttgac tcgtggggag gccctcacaa tatcttggat tcttctgagg     1080

ttttgaaaac cgtgtctgcc attgtggacg ccggctcctc catcaacctc tacatgttcc     1140

acggaggcac caactttggc ttcatgaatg gagccatgca cttccatgac tacaagtcag     1200

atgtcaccag ctatgactat gatgctgtgc tgacagaagc cggcgattac acggccaagt     1260

acatgaagct tcgagacttc ttcggctcca tctcaggcat ccctctccct cccccacctg     1320

accttcttcc caagatgccg tatgagccct taacgccagt cttgtacctg tctctgtggg     1380

acgccctcaa gtacctgggg gagccaatca agtctgaaaa gcccatcaac atggagaacc     1440

tgccagtcaa tgggggaaat ggacagtcct tcgggtacat tctctatgag accagcatca     1500

cctcgtctgg catcctcagt ggccacgtgc atgatcgggg gcaggtgttt gtgaacacag     1560

tatccatagg attcttggac tacaagacaa cgaagattgc tgtccccctg atccagggtt     1620

acaccgtgct gaggatcttg gtggagaatc gtgggcgagt caactatggg gagaatattg     1680

atgaccagcg caaaggctta attggaaatc tctatctgaa tgattcaccc ctgaaaaact     1740

tcagaatcta tagcctggat atgaagaaga gcttctttca gaggttcggc ctggacaaat     1800

ggagttccct cccagaaaca cccacattac ctgctttctt cttgggtagc ttgtccatca     1860

gctccacccc ttgtgacacc tttctgaagc tggagggctg ggagaagggg gttgtattca     1920

tcaatggcca gaaccttgga cgttactgga acattggacc ccagaagacg ctttacctcc     1980

caggtccctg gttgagcagc ggaatcaacc aggtcatcgt ttttgaggag acgatggcgg     2040

gccctgcatt acagttcacg gaaacccccc acctgggcag gaaccagtac attaagtgag     2100

cggtggcacc ccctcctgct ggtgccagtg ggagactgcc gcctcctctt gacctgaagc     2160

ctggtggctg ctgccccacc cctcactgca aaagcatctc cttaagtagc aacctcaggg     2220

actgggggct acagtctgcc cctgtctcag ctcaaaaccc taagcctgca gggaaaggtg     2280

ggatggctct gggcctggct ttgttgatga tggctttcct acagccctgc tcttgtgccg     2340

aggctgtcgg gctgtctcta gggtgggagc agctaatcag atcgcccagc ctttggccct     2400

cagaaaaagt gctgaaacgt gcccttgcac tggacgtcac agccctgcga gcatctgctg     2460

gactcaggcg tgctctttgc tggttcctgg gaggcttggc cacatccctc atggccccat     2520

tttatccccg aaatcctggg tgtgtcacca gtgtagaggg tggggaaggg gtgtctcacc     2580

tgagctgact ttgttcttcc ttcacaacct tctgagcctt ctttgggatt ctggaaggaa     2640

ctcggcgtga gaaacatgtg acttcccctt tcccttccca ctcgctgctt cccacagggt     2700

gacaggctgg gctggagaaa cagaaatcct caccctgcgt cttcccaagt tagcaggtgt     2760

ctctggtgtt cagtgaggag gacatgtgag tcctggcaga agccatggcc catgtctgca     2820

catccaggga ggaggacaga aggcccagct cacatgtgag tcctggcaga agccatggcc     2880

catgtctgca catccaggga ggaggacaga aggcccagct cacatgtgag tcctggcaga     2940

agccatggcc catgtctgca catccaggga ggaggacaga aggcccagct cagtggcccc     3000

cgccccccac cccccacgcc cgaacagcag gggcagagca gccctccttc gaagtgtgtc     3060

caagtccgca tttgagcctt gttctggggc ccagcccaac acctggcttg ggctcactgt     3120

cctgagttgc agtaaagcta taaccttgaa tcacaaaaaa aaaaaaaaaa aaaaaaaa       3178


<210>  1249
<211>  7667
<212>  DNA
<213>  homo sapiens

<400>  1249
gtccgggttc gcttgcctcg tcagcgtccg cgtttttccc ggcccccccc aacccccccg       60

gacaggaccc ccttgagctt gtccctcagc tgccaccatg agcgaccaag atcactccat      120

ggatgaaatg acagctgtgg tgaaaattga aaaaggagtt ggtggcaata atgggggcaa      180

tggtaatggt ggtggtgcct tttcacaggc tcgaagtagc agcacaggca gtagcagcag      240

cactggagga ggagggcagg agtcccagcc atcccctttg gctctgctgg cagcaacttg      300

cagcagaatt gagtcaccca atgagaacag caacaactcc cagggcccga gtcagtcagg      360

gggaacaggt gagcttgacc tcacagccac acaactttca cagggtgcca atggctggca      420

gatcatctct tcctcctctg gggctacccc tacctcaaag gaacagagtg gcagcagtac      480

caatggcagc aatggcagtg agtcttccaa gaatcgcaca gtctctggtg ggcagtatgt      540

tgtggctgcc gctcccaact tacagaacca gcaagttctg acaggactac ctggagtgat      600

gcctaatatt cagtatcaag taatcccaca gttccagacc gttgatgggc aacagctgca      660

gtttgctgcc actggggccc aagtgcagca ggatggttct ggtcaaatac agatcatacc      720

aggtgcaaac caacagatta tcacaaatcg aggaagtgga ggcaacatca ttgctgctat      780

gccaaaccta ctccagcagg ctgtccccct ccaaggcctg gctaataatg tactctcagg      840

acagactcag tatgtgacca atgtaccagt ggccctgaat gggaacatca ccttgctacc      900

tgtcaacagc gtttctgcag ctaccttgac tcccagctct caggcagtca cgatcagcag      960

ctctgggtcc caggagagtg gctcacagcc tgtcacctca gggactacca tcagttctgc     1020

cagcttggta tcatcacaag ccagttccag ctcctttttc accaatgcca atagctactc     1080

aactactact accaccagca acatgggaat tatgaacttt actaccagtg gatcatcagg     1140

gaccaactct caaggccaga caccccagag ggtcagtggg ctacaggggt ctgatgctct     1200

gaacatccag caaaaccaga catctggagg ctcattgcaa gcaggccagc aaaaagaagg     1260

agagcaaaac cagcagacac agcagcaaca aattcttatc cagcctcagc tagttcaagg     1320

gggacaggcc ctccaggccc tccaagcagc accattgtca gggcagacct ttacaactca     1380

agccatctcc caggaaaccc tccagaacct ccagcttcag gctgttccaa actctggtcc     1440

catcatcatc cggacaccaa cagtggggcc caatggacag gtcagttggc agactctaca     1500

gctgcagaac ctccaagttc agaacccaca agcccaaaca atcaccttag ccccaatgca     1560

gggtgtttcc ttggggcaga ccagcagcag caacaccact ctcacaccca ttgcctcagc     1620

tgcttccatt cctgctggca cagtcactgt gaatgctgct caactctcct ccatgccagg     1680

cctccagacc attaacctca gtgcattggg tacttcagga atccaggtgc acccaattca     1740

aggcctgccg ttggctatag caaatgcccc aggtgatcat ggagctcagc ttggtctcca     1800

tggggctggt ggtgatggaa tacatgatga cacagcaggt ggagaggaag gagaaaacag     1860

cccagatgcc caaccccaag ccggtcggag gacccggcgg gaagcatgca cctgccccta     1920

ctgtaaagac agtgaaggaa ggggctcggg ggatcctggc aaaaagaaac agcatatttg     1980

ccacatccaa ggctgtggga aagtgtatgg caagacctct cacctgcggg cacacttgcg     2040

ctggcataca ggcgagaggc catttatgtg tacctggtca tactgtggga aacgcttcac     2100

acgttcggat gagctacaga ggcacaaacg tacacacaca ggtgagaaga aatttgcctg     2160

ccctgagtgt cctaagcgct tcatgaggag tgaccacctg tcaaaacata tcaagaccca     2220

ccagaataag aagggaggcc caggtgtagc tctgagtgtg ggcactttgc ccctggacag     2280

tggggcaggt tcagaaggca gtggcactgc cactccttca gcccttatta ccaccaatat     2340

ggtagccatg gaggccatct gtccagaggg cattgcccgt cttgccaaca gtggcatcaa     2400

cgtcatgcag gtggcagatc tgcagtccat taatatcagt ggcaatggct tctgagatca     2460

ggcacccggg gccagagaca tatgggccat accccttaac cccgggatgc aaggtagcat     2520

gggtccaaga gacatggaag agagagccat gaagcattaa aatgcatggt gttgagaaga     2580

atcaggagag ggatacaaga gaggagatgg ggtcccggca cccatctgta tcatcagtgc     2640

ctctttgaag gtgggaaaca ttagtgaaaa ttctgttggt gccacgcttt gatgagcatt     2700

tgtttgaccc cagtttcttc ttacacttct taccccagcc tacccttcct gcatttctct     2760

tctcagctct tccatgatgg attccccccc ctttcctaaa gccatcatgc cttgataaat     2820

atatatgatc attgaaatac tttttaacaa aaaacagatt ctatattatt atatatatat     2880

atatatatat aaagatatat agagatgcat tcacaggggt tggctgggag gaggaagacc     2940

attctgtgac caaaatacct tggtcatttt ttttatattg ccttatttcc ctatggctga     3000

gccttgttgt gacacatcaa gcttttctgt agatgttgtc ttggcttccc accagcttaa     3060

gcgttcatat gctctgcttt tagttcatat atacatacat aatgtttttc ctttcttaat     3120

tttgtctttt tgtttgggat cagcttcttg cactccttcc ctaactcaac tgttgccgtc     3180

tcatcttctc tcatctgatc acttcatgtt ttgtttttgt tactgcctgg atgaggcact     3240

tctgtcaatt ttttcaggac cttagttcca gcagcagaat ggaaaaatcc ttgaagccca     3300

ggctgatgct tgaagtaact gtggagggag tgttcaaaat actactgacg caggcacctt     3360

cttggcgctg gagagtcaaa ggcatctccc ttcattagct gctctgagca tcaagaatta     3420

gaagtctttc agtggaattg tacaagagtc cctttgaaga taataatctt ggctcagttt     3480

gtataaactg tcaaattttc aaataatagg tagggggctt tcactaggaa aatcatgtgc     3540

tcagaagagg aaatgactcg tagtcaggtt caggagttag tggagtattt ggactttggt     3600

actgctgtct tccaaggtag ctctaagttt tgatgtgtgg gcttctgagt ttatattctg     3660

aaaggaaata cacttctttt gaacatcccc actaggttct tttccattgt caataaggag     3720

catcagccag tgaatctgtt tcaggtttcc attctgcaga actcctccaa agcatgtgct     3780

agtggcaaga cagtggttct tatgatgttt tcccttaact tttccttgta tgttcttggg     3840

tggttcctaa gggaaaggga agcacatgat catgggaatg atagcccaga acaaaaagaa     3900

atcttgtctt accacagtgt tttataggag agattgggag aaatcatcct gttttctctg     3960

tgacctgatt tcagaagaga ctgatccaaa aattataacg gcagggaacc tagtgcattt     4020

ggcactgaga tttaaatgca accagaattg tcctcaaggc ccagccataa aagcattgtc     4080

tctctcgacc ttctggtatc ttgttagaga gcttttcact gtgaggaagt gtggaaaaat     4140

agctctgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtaatctgtt aggttgggga     4200

taggttttct gctagccaat attaaaagag acctgcaata aaaaaattac cctgatctga     4260

tagaaagcaa gtgtttttgt atgtgtgggt gaatgtgtgt tcatgcccgt atatgtctac     4320

acacagatga caaattatat ttgaaatcgt tggaaaataa attcagatca aaatgccttt     4380

caggcccatt acctagaaat ctatcttaaa acctgggtat gttcctaagg tcatttcttt     4440

gcttatgcta aattaattac aattatgaat ggaggatatt ctactgtact tttttaaaaa     4500

gaaactattt ttgtgtttga aagtgaaacc aacatccaga tctatagcag agtccttatt     4560

cttctcataa atctttttac tttggctaca aatagatgat ggtatgattc tattatatat     4620

tttatataaa atccatccaa attaagtttt gggtaagtgt gttgtttaat ctgaactata     4680

gtaacttaat actctaaaca atagttcact ccatttggtc ctttctccac agatgtaatt     4740

atgttttcaa ctcaggaact atggcaagga actttcccca gatcaaattc tattaacgct     4800

gagatacaag tcatccatgc acagccacta tcataccctt tattctcact gaaaggcaga     4860

actcagaacc tgttatttta tgtctgtaat catgtacttt ggcatctttt ggaggaaagg     4920

ggcaggataa ctcactggaa tgtacagtat tttgctagtg catttcaagg aatggaatct     4980

tctccagtat gaaattacca gatataaaat aatgtaatga tgctgaggat ataagctttt     5040

agaaggtaat ttgatggtat ttctttctcg aatgaaaagc tgctggttta ccctcaaccc     5100

tattcattag cattaccatg agtgaattta tatctaatta tttccacttg ccctgttctc     5160

ttcacaccaa ggaagctcca gatccagtat cttgtttggc ctcaaaacag aagcagcttc     5220

ttttgtctcc cagcagtagt gagccactca gtctcttcca caggaagttt ggagcctaca     5280

ttccttgagt caggagctta ttacagaaaa accccgtttc cctgaacttt tggctaacag     5340

aaattaattt aactgacatg catattgatt ctgaaatttt tttcctaagt ttttttcatt     5400

tttttgaatg agttttttaa attttttaga tgaccaaaac ttgcagggca ggggatgccc     5460

agaagagtgg tgagatagta aaacacttat tccctcatcc tttcaggttt tcaggttgcc     5520

catttatatt catttacatg tcatttgact gtctcacttt ttacccagaa cagtaacaac     5580

ccacaccgtc ttccttcagg gatttccaac tggcactctg tgggtgctac acagaatgca     5640

atttaatgga tatttctcag cctggttcag aataaattga tcctttgatc ccagaaagta     5700

tatactgaag tgtgggataa agattatgat taggggaggg ttggagacaa aagctgtaaa     5760

ttactatggc tgatttattt ctactatata catatatatt ttttgctttt gtatatccta     5820

tataggaaac taagcattgt atttttttta acaaatctaa aaaagcacta tgaactacag     5880

gtgtttgact ttcaaaatat attttgtatt gttaatatct tcacattgtg tgaatactgg     5940

aagctgcaga tctttgctag gacgcaataa atttatatac tttttgaggg gttcttctgg     6000

ggtgctaatc aggcccctgt tatgcttagg gggagccctg gtgctacttg cttgaagttt     6060

tcagtgtaag taccctgatg ccttttggac cttgggatca gatcaagagt tttggagatc     6120

aggtaccaag gaaataagga cagtctagct gcctcaagtg aggggccctt tgcatagctc     6180

tccttccccc tcactgaagc tgggtagcct attggggttg agagggaaaa tgtgaaatct     6240

cagaatttat ctcccttaga agagagccag taacttatgt acaaggatga aagaaaggtc     6300

gcagcagtag ctttggggaa agggaggaag atatggcact tctccaaccc cggaaaacat     6360

tgcttttgaa aactgctgat aaaatatgag ccggttatta cttctgtttg ggagactgtg     6420

ctctctgtgg tgcctctctt ggctctactc cacagatacc agacctcttc taagaggatg     6480

agcagaccag ctttgaggtt gacctgtttc tctttgtctg ccttcccaaa acaccagccc     6540

ccaggaagac attaagcagc cttaagctta aattcctact ccctcttcca aatttggctc     6600

acttgcctta gatccaaggc agggaaagga aaagaagggg ggtctctggc tttattactc     6660

ccctaagtct ttactctgac ttccccaaac ccagaaagat tttctccaca gtgttcattt     6720

gaaagaggag tattttgtcc cattttcccc ttcctcatta tcaaacagcc ccagtcttcc     6780

ttgtctctgc taagaaagta gaggcatgat gatctgcctc tcaactgccc taagtcctag     6840

ctaagtatca ggggaaaaaa aaaaaaaaaa agcctaacaa atgggattag actagggctg     6900

caagtagtga ggattttgtt gatacctctg ctgggatgtg tgctttccca tatcttgcct     6960

tcaggaatta cactgtgcct tttccccagg gatatgggct ctgtctaccc agtgctccag     7020

tttcccggta actgctcttg aacattgtgg acaagggcag gtcttcatat ttttgatcat     7080

ccctttctcc cagtgaaatc ccatagccct tacctagagt ctagggcaca aagacttcgg     7140

ggaagataca ctgagattga cctgaggaga catctacaca caccagtggc agctgcccca     7200

gggcctgctt ccccttccta agtctgtcat cctctggaag ggatgggtgg tgctccaatc     7260

tctggtgcct aaaaacccaa gtttatttct ctcttaacac tggcaataac cagtccacac     7320

cactgttgcc ttttaaaacc tcttaataat ctcatgctgt gtttgttttg attccaatcc     7380

aattatcacc agggctgtgt gggtaaatgc ttttaaatgc tctctcatct tgttcttccc     7440

cctcaccccc cactcttagg tatgtatgat gctaatcttg tccctaagta agtttcttcc     7500

tgctcctttt gtatcttcct ttcttgtctt tcctcctacc ttttgtctct tggtgttttg     7560

ggactttttt tttttttttt ttggcctttt gtacaaagat tagtttcaat gtagtctgta     7620

gcctcctttg taaaccaatt aaaaagtttt ttaataaaaa aaaaaaa                   7667


<210>  1250
<211>  1095
<212>  DNA
<213>  homo sapiens

<400>  1250
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgaggaa aggccctggt ctccggagtt tcctcgcatt aaaggagaga gagagagagt     1020

actcttttgg gcaacggccc tccaaaattg cccccacatt ggctgcctta taaatatgtc     1080

tgtgtgttga ctggt                                                      1095


<210>  1251
<211>  4012
<212>  DNA
<213>  homo sapiens

<400>  1251
gtgggagccc gcgaggtggc ccgagcgagg gccccgcatc cccgcagagc ccgcccgagg       60

gcgcagcctg ccacgccagg ggaggcggcc gggcggcggg gaacggcggg ggcggagcgc      120

agcctcccga cgccgccgcc tcaccgcccc cctccgcctc ctcggcctcc gctcgcagcc      180

gccgcctccg cctccgccgg gctgaggagc cgggagtccg ccgcgccggc tcggggctgc      240

gggatgggga gttagcgcca cggcggcggc agtggccgca gcgcaccccg ccgccgccca      300

ggagcccgtc cagccagggg tgccgggccc gcccagcccg ccccggagcc aggcccgcgg      360

gcggcggcgg agctgggcag gtggatgcgg ctggaagatg gcgccctcgg gcccgggcag      420

cagcgccagg cggcggtgcc ggcgggtgct gtactggatc ccggtggtgt tcatcaccct      480

cctgctcggc tggtcctact acgcctacgc catccagctg tgcatagtgt ccatggaaaa      540

cactggcgaa caagttgtgt gcctgatggc ctatcatcta ctttttgcaa tgtttgtctg      600

gtcatactgg aaaactatct ttacattacc aatgaatcct tcaaaagaat tccatctctc      660

ttatgcagag aaagatttgt tggagagaga gccaagagga gaagcccatc aggaagttct      720

taggcgagca gccaaggatc ttcccatcta taccaggacc atgtctggag ccatccgata      780

ctgtgacaga tgccaactta taaaaccaga tcgctgccat cactgctccg tctgtgataa      840

atgtattttg aagatggatc atcattgtcc atgggtgaac aattgtgttg gattttcaaa      900

ttataagttc tttctccttt tcttggctta ttctctgctc tactgccttt ttattgcggc      960

aacagattta cagtatttta tcaaattttg gacaaatggc ctacctgata ctcaagccaa     1020

gttccatatt atgtttttat tctttgctgc agctatgttt tctgtcagct tgtcttctct     1080

gtttggctat cattgttggc tagtcagcaa aaataaatct acattagagg cattcagaag     1140

tccagtattt cgacatggaa cagataagaa tggattcagc ttgggtttca gtaaaaacat     1200

gcgacaagtt tttggtgatg agaagaagta ctggttgcta cccatttttt caagtctagg     1260

tgatggctgc tcctttccaa cttgccttgt taaccaggat cctgaacaag catctactcc     1320

tgcagggctg aattccacag ctaaaaatct cgaaaaccat cagtttcctg caaagccatt     1380

gagagagtcc cagagccacc ttcttactga ttctcagtct tggacggaga gcagcataaa     1440

cccaggaaaa tgcaaagctg gtatgagcaa tcctgcatta accatggaaa atgagactta     1500

actcttcaag caagataaat tcatacttta taaaagtatc aatgctgtag atggatggaa     1560

gaggcttccc acaggaaggt gccaccagtc agttgtgcct atgtcccttt ggctggaaat     1620

gcagaatatg aattgattag ttctctccaa gccattgctt aaaatataac atgttttgga     1680

tccaatacac acattgttac aactaacaca aattcctatt aaatattaaa agtagttctg     1740

gtttattaat caacggggaa aacatcttct ccaaaaaact tggaataaat ccaaggacca     1800

gtttttaccc aaatatatgg gtagcacagt ttatcacata gaaactccat taatcatctg     1860

attttccgaa tctgaaaatt gagactatta agatattagg atttcagaga tttcaagtca     1920

cattataatg ataagcatta ttcataaaac ttgttacctt taagaaggtg gaagtggcaa     1980

accatacttc ttttttttcc tctgatgtga atccagcctc agactgagtg aactgtaata     2040

attatgaatt cattacagag tccaggtggc ctgcagttga agatcatcaa ccatttttgc     2100

ctcacttaat tccagccttt tgttttctgc tggaaaataa gtgtggacat tgaagcttga     2160

gctctcaaag cagttggctg gaatactttt gtcagaatac ggtacatttc tattacatca     2220

gaaatatatt ttcatctctt cttgttaaat tgggaggaaa tttatgatag caattatgaa     2280

gattgtttta tgacattctt ttgtcagttt ggctttctaa aaatctcttt ttagattatt     2340

tctcctgttg aacatagtaa aactattgaa tttctcttaa gaattcctaa taggtcaata     2400

gatttaccct ccagtgatat ctatattatt tctttctcgt ctcatcaaaa tgatgacagg     2460

taaactatat ttttccttaa acacctatta cagttaaatt atgcaaatca ttaaataaaa     2520

atcatacaac ttttggaaag ttagttcaac atgaactaaa atggcatgct atttggaaat     2580

ttagtttgag ataaactaaa gtgtgttgat gccagaatgt tcagcttcag taaatataat     2640

aagctcttgt gccttgtatg cactatttaa aaaaagtttt ttttatttga gtccagtata     2700

attcatgtaa atgttaacaa ttagaataat actctgtatg cttttttgat actgattttg     2760

agaatttaaa gcagattacc ttttaaaact ggaccaacta agtaattggt atttaatcaa     2820

agagaaaatg gtaataaact tttcaaaatc tttgttaaac caaacattca acacaaaata     2880

aactagaagg ccagaggata atggaataaa agatcattgc aattacttat ccttcctaaa     2940

aatatagttt tatattaatt gtgcttatgg aagaaacaat gtcagccaag tccattttat     3000

agtttgagtg caattctttg aacaatagaa atatctgcag tctttcacag atttgtatta     3060

tgctgaagag tttcatctga caatctgctt caagaaatct cagaaaatat gataacattt     3120

taactttcat tttagagcac gttttggtca tttttaaaaa tacctaaagt gccagaccgg     3180

aacctatagc tactgctaga agtcttaaaa aaaccaacag cagcacagga tgtattaaga     3240

attatatgaa gtcaggtttg tttttttttt tttttttttt tcaaagcaca gtactgttag     3300

ctgtttttgt ggacaggatt cgattaagta ttccctcttg tcaaactgga agctagggga     3360

aaaagaggga tttttatcct ttactcttct agagtactgt taatgcccct ttcccacagt     3420

cttttatata attaaatata tgtcaataca cattagaatc agatttgaaa aagttaaaac     3480

aatttcattg ttgtaattgt tccctttctg ttttcatata gtgaataacc tttaaagggt     3540

tgttttgttt tgttttgaat tataggagtt ataatctttg gagatgattg catatctcat     3600

tagatatgca atataaattt atctgagtga acaaagtgct aaataaatag atctacattt     3660

tgtacatatt tatataaaat ttacctttaa gtatttactt taaaaaattt aatggcttaa     3720

ctcgaacttg aagacacata cttcaactgt ccttattgtc cattaaactg ataattttga     3780

tttttcttgc ttttatagat tttactatat aggaatcaag atttaagaaa ttttgcatta     3840

aaaatagtgt accaatgctt catatacgtt agttatttgc tattatgtag ggaagaggat     3900

tgttatttca aagatatatt aaagaacagt tgcatctgaa tataatcatg atgcattcaa     3960

tgaagttcat atccatgaat tcactcctaa tataccctaa taaagtggtt ga             4012


<210>  1252
<211>  5443
<212>  DNA
<213>  homo sapiens

<400>  1252
ctcccagcgg cggcggctgc agcgcggcgg tccgagcggg tgcaccgcgg cggaggaggc       60

agcatcccgc ggcgctgacg gtcctgggga gagcatggcg ccgaggtgcc cctggccatg      120

gccgcggcgg cggcgcctcc tggacgtgct cgcgcccctg gtcctgctgc tcggggtccg      180

cgcggcctcc gcggagccag agcgcatcag cgaggaggtg gggctgctgc agctccttgg      240

ggaccccccg ccccagcagg tcacccagac ggatgacccc gacgtcgggc tggcctacgt      300

ctttgggcca gatgccaaca gtggccaagt ggcccggtac cacttcccca gcctcttctt      360

ccgtgacttc tcactgctgt tccacatccg gccagccaca gagggcccag gggtgctgtt      420

cgccatcacg gactcggcgc aggccatggt cttgctgggc gtgaagctct ctggggtgca      480

ggacgggcac caggacatct ccctgctcta cacagaacca ggtgcaggcc agacccacac      540

agccgccagc ttccggctcc ccgccttcgt cggccagtgg acacacttag ccctcagtgt      600

ggcaggtggc tttgtggccc tctacgtgga ctgtgaggag ttccagagaa tgccgcttgc      660

tcggtcctca cggggcctgg agctggagcc tggcgccggg ctcttcgtgg ctcaggcggg      720

gggagcggac cctgacaagt tccagggggt gatcgctgag ctgaaggtgc gcagggaccc      780

ccaggtgagc cccatgcact gcctggacga ggaaggcgat gactcagatg gggcatccgg      840

agactctggc agcgggctcg gggacgcccg ggagcttctc agggaggaga cgggcgcggc      900

cctaaaaccc aggctccccg cgccaccccc cgtcaccacg ccacccttgg ctggaggcag      960

cagcacggaa gattccagaa gtgaagaagt cgaggagcag accacggtgg cttcgttagg     1020

agctcagaca cttcctggct cagattctgt ctccacgtgg gacgggagtg tccggacccc     1080

tgggggccgc gtgaaagagg gcggcctgaa ggggcagaaa ggggagccag gtgttccggg     1140

cccacctggc cgggcaggcc ccccaggatc cccatgccta cctggtcccc cgggtctccc     1200

gtgcccagtg agtcccctgg gtcctgcagg cccagcgttg caaactgtcc ccggaccaca     1260

aggaccccca gggcctccgg ggagggacgg cacccctgga agggacggcg agccgggcga     1320

ccccggtgaa gacggaaagc cgggcgacac cgggccacaa ggcttccccg ggactccagg     1380

ggacgtaggt cccaagggcg acaagggaga ccctggggtt ggagagagag ggcccccagg     1440

accccaaggg cctccagggc ccccaggacc ctccttcaga cacgacaagc tgaccttcat     1500

tgacatggag ggatctggct tcgggggcga tctggaggcc ctgcggggtc ctcgaggctt     1560

ccctggacct cccggacccc ccggtgtccc aggcctgccc ggcgagccag gccgctttgg     1620

ggtgaacagc tccgacgtcc caggacccgc cggccttcct ggtgtgcctg ggcgcgaggg     1680

tccccccggg tttcctggcc tcccgggacc cccaggccct ccgggaagag aggggccccc     1740

aggaaggact gggcagaaag gcagcctggg tgaagcaggc gccccaggac ataaggggag     1800

caagggagcc cccggtcctg ctggtgctcg tggggagagc ggcctggcag gagcccccgg     1860

acctgctgga ccaccaggcc cccctgggcc ccctgggccc ccaggaccag gactccccgc     1920

tggatttgat gacatggaag gctccggggg gcccttctgg tcaacagccc gaagcgctga     1980

tgggccacag ggacctcccg gcctgccggg acttaagggg gatcctggcg tgcctgggct     2040

gccgggggcg aagggagaag ttggagcaga tggagtcccc gggttccccg gcctccctgg     2100

cagagagggc attgctgggc cccaggggcc aaagggagac agaggcagcc ggggagaaaa     2160

gggagatcca gggaaggacg gagtcgggca gccgggcctc cctggccccc ccggaccccc     2220

gggacctgtg gtctacgtgt cggagcagga cggatccgtc ctgagcgtgc cgggacctga     2280

gggccggccg ggtttcgcag gctttcccgg acctgcagga cccaagggca acctgggctc     2340

taagggcgaa cgaggctccc cgggacccaa gggtgagaag ggtgaaccgg gcagcatctt     2400

cagccccgac ggcggtgccc tgggccctgc ccagaaagga gccaagggag agccgggctt     2460

ccgaggaccc ccgggtccat acggacggcc ggggtacaag ggagagattg gctttcctgg     2520

acggccgggt cgccccggga tgaacggatt gaaaggagag aaaggggagc cgggagatgc     2580

cagccttgga tttggcatga ggggaatgcc cggcccccca ggacctccag ggcccccagg     2640

ccctccaggg actcctgttt acgacagcaa tgtgtttgct gagtccagcc gccccgggcc     2700

tccaggattg ccagggaatc agggccctcc aggacccaag ggcgccaaag gagaagtggg     2760

cccccccgga ccaccagggc agtttccgtt tgactttctt cagttggagg ctgaaatgaa     2820

gggggagaag ggagaccgag gtgatgcagg acagaaaggc gaaagggggg agcccggggg     2880

cggcggtttc ttcggctcca gcctgcccgg cccccccggc cccccaggcc cacgtggcta     2940

ccctgggatt ccaggtccca agggagagag catccggggc cagcccggcc cacctggacc     3000

tcagggaccc cccggcatcg gctacgaggg gcgccagggc cctcccggcc ccccaggccc     3060

cccagggccc ccttcatttc ctggccctca caggcagact atcagcgttc ccggccctcc     3120

gggcccccct gggccccctg ggccccctgg aaccatgggc gcctcctcag gggtgaggct     3180

ctgggctaca cgccaggcca tgctgggcca ggtgcacgag gttcccgagg gctggctcat     3240

cttcgtggcc gagcaggagg agctctacgt ccgcgtgcag aacgggttcc ggaaggtcca     3300

gctggaggcc cggacaccac tcccacgagg gacggacaat gaagtggccg ccttgcagcc     3360

ccccgtggtg cagctgcacg acagcaaccc ctacccgcgg cgggagcacc cccaccccac     3420

cgcgcggccc tggcgggcag atgacatcct ggccagcccc cctcgcctgc ccgagcccca     3480

gccctacccc ggagccccgc accacagctc ctacgtgcac ctgcggccgg cgcgacccac     3540

aagcccaccc gcccacagcc accgcgactt ccagccggtg ctccacctgg ttgcgctcaa     3600

cagccccctg tcaggcggca tgcggggcat ccgcggggcc gacttccagt gcttccagca     3660

ggcgcgggcc gtggggctgg cgggcacctt ccgcgccttc ctgtcctcgc gcctgcagga     3720

cctgtacagc atcgtgcgcc gtgccgaccg cgcagccgtg cccatcgtca acctcaagga     3780

cgagctgctg tttcccagct gggaggctct gttctcaggc tctgagggtc cgctgaagcc     3840

cggggcacgc atcttctcct ttgacggcaa ggacgtcctg aggcacccca cctggcccca     3900

gaagagcgtg tggcatggct cggaccccaa cgggcgcagg ctgaccgaga gctactgtga     3960

gacgtggcgg acggaggctc cctcggccac gggccaggcc tcctcgctgc tggggggcag     4020

gctcctgggg cagagtgccg cgagctgcca tcacgcctac atcgtgctct gcattgagaa     4080

cagcttcatg actgcctcca agtagccacc gcctggatgc ggatggccgg agaggaccgg     4140

cggctcggag gaagccccca ccgtgggcag ggagcggccg gccagcccct ggccccagga     4200

cctggctgcc atactttcct gtatagttca cgtttcatgt aatcctcaag aaataaaagg     4260

aagccaaaga gtgtattttt ttaaaagttt aaaacagaag cctgatgctg acattcacct     4320

gccccaactc tcccctgacc tgtgagccca gctgggtcag gcagggtgca gtatcatgcc     4380

ctgtgcaacc tcttggcctg atcagaccac ggctcgattt ctccaggatt tcctgctttg     4440

ggaagccgtg ctcgccccag caggtgctga cttcatctcc cacctagcag caccgttctg     4500

tgcacaaaac ccagacctgt tagcagacag gccccgtgag gcaatgggag ctgaggccac     4560

actcagcaca aggccatctg ggctcctcca gggtgtgtgc tcgccctgcg gtagatggga     4620

gggaggctca ggtccctggg gctaggggga gccccttctg ctcagctctg ggccattctc     4680

cacagcaacc ccaggctgaa gcaggttccc aagctcagag gcgcactgtg acccccagct     4740

ccggcctgtc ctccaacacc aagcacagca gcctggggct ggcctcccaa atgagccatg     4800

agatgataca tccaaagcag acagctccac cctggccgag tccaagctgg gagattcaag     4860

ggacccatga gttggggtct ggcagcctcc catccagggc ccccatctca tgcccctggc     4920

tgggacgtgg ctcagccagc acttgtccag ctgagcgcca ggatggaaca cggccacatc     4980

aaagaggctg aggctggcac aggacatgcg gtagccagca cacagggcag tgagggaggg     5040

ctgtcatctg tgcactgccc atggacaggc tggctccaga tgcagggcag tcattggctg     5100

tctcctagga aacccatatc cttaccctcc ttgggactga aggggaaccc cggggtgccc     5160

acaggccgcc ctgcgggtga acaaagcagc cacgaggtgc aacaaggtcc tctgtcagtc     5220

acagccaccc ctgagatccg gcaacatcaa cccgagtcat tcgttctgtg gagggacaag     5280

tggactcagg gcagcgccag gctgaccaca gcacagccaa cacgcacctg cctcaggact     5340

gcgacgaaac cggtggggct ggttctgtaa ttgtgtgtga tgtgaagcca attcagacag     5400

gcaaataaaa gtgacctttt acactgaaaa aaaaaaaaaa aaa                       5443


<210>  1253
<211>  2418
<212>  DNA
<213>  homo sapiens

<400>  1253
ggccacacgc gcgcacccac ccgcgcgcac ccagcccccg ggagaggcag gaagggaggc       60

ggcggcgcga ggaggaggga gcggccgtgg agcccaatcg ttcgctcccc ttcccgggtc      120

cgcgcgcggc gccgcctccg ccattgctgc gagcaggagc aggagacgcg gagctcggag      180

cgctgagctg acctgccgga gccgggcgtg ggctgcagcc tcggagctcc cggaacgatg      240

gtgaagttgg ggaacaattt cgcagagaag ggcaccaagc agccgctgct ggaggatggc      300

ttcgacacca ttcccctgat gacgcccctc gatgtcaatc agctgcagtt cccgcccccg      360

gataaggtgg tcgtgaaaac taagaccgag tatgaacctg accgcaagaa agggaaagca      420

cgtcctcccc aaattgctga gttcaccgtc agcatcacgg agggtgtcac cgagaggttt      480

aaggtctccg tgttggtcct cttcgccctg gccttcctca cctgcgtcgt cttcctggtt      540

gtctacaagg tgtacaagta tgaccgcgcc tgccccgatg ggttcgtcct caagaacacc      600

cagtgcatcc cagaaggctt ggagagctac tacgcggagc aagactccag tgcccgggag      660

aaattttaca cagtcataaa ccactacaac ctggccaagc agagcatcac gcgctccgta      720

tcgccctgga tgtcagttct gtcagaagag aagctgtccg agcaggagac tgaagcggct      780

gagaagtcag cttagcggga tgggcaagtt ccttacaatg tgtcacttgc aaataacaaa      840

gggactttga gggacatttc attaaatata attactgata ctttagaggt tactcattta      900

cggtgcaatt gcttctgttt gctaatgctg ctttgcaaat aaaacttgct gccgaccacc      960

cacgggcata aaatcaagtg catttcagca ttgcctaaag agctctgaca ccacttttca     1020

tgttaagatc ttcatttagc tcctttactg ggatttattg gatgctgtaa aaaaataaat     1080

ttacactgga tatgcgaagg gtttggatct cagataaatg cattttgtgg aattgatttt     1140

ctgaaccgac cctgctgtct gcaaaccttc ctccatagcc atatctagag tgatctctcg     1200

ctgtgctaag agcaagccta cttcgcattt cttcctcggc catcagcggg taacagtgct     1260

gactgctgcc aaggtgcact gtagtaagta agtggcatag agaacgagga aaaagacccc     1320

cccacccctc cctgtgctga ctcctgagtc ggggtgggac ggccctgcaa tgtggcaggc     1380

tcggtgtgga ttgactactc cctcccctct gactctggca tcttggtaag gagggagggg     1440

caccacccat ctgggtggag acagctgggg tttgctccag tgtgtgtaga ctggcagagc     1500

atgtgaggga gagggctggg aagagacggc cctgggcccg tgaggtgcag aactctccct     1560

gcaggtagtc tgtctgctct gtgatgtgct gataggaaag agcccccact ggccctctgg     1620

ttcacttcta ttatgaataa atttgcacca atagccccat tagtttttaa agaaatgagc     1680

tgggtgggaa aagtggaaat gtaatttctg gtaagcttga gctactttaa tttttattct     1740

atgaaactga tatcccttga tgtgggaaac aggcaggaaa ggctgtgggg tgggggtggg     1800

ggactggtgt ggcaccgtgc aaacaaaatg acaaatttca actcacaatc tttgtaagaa     1860

aattgttcca gtttgaatct tgatattaaa gtttatgttt acaaaactgc cagttagatg     1920

aactaagtgt gtaaaacaaa tagaaaagac attcgcagac atttcttcta tgttattgaa     1980

tgtgttgttt ctggtgtacg tgtcaaaagt ttcagttttt tagatcagaa ataaacgaca     2040

aatagtgtga gatgtgttgt gaacaggcat ggtgaccgtg gtcagcgcca ctcttgtttc     2100

ctgaaatgtg cttctaagac agaaaatgta ttttctcatc aagggtgtct ggagacacag     2160

accgtgacct tggcgcagcg gtgtgcatca gaggcgtgtg ctgagaaggg tggtgttaag     2220

ctgtggaaaa tgactcaaga gcaataaatc agtgccaaag cttccctgcg catctgaata     2280

gacacaagtg aagcccgtgt gcgcacagtg cagaggccga gcctgtattt ccaggtagac     2340

gtggacttta ttgactgtga attcatttac atgtaacttc tgacatttca ctctgtgcaa     2400

ataaagaaca tgaggata                                                   2418


<210>  1254
<211>  2580
<212>  DNA
<213>  homo sapiens

<400>  1254
ataaggtatg aaagatgtgg cctgcagaga gccggcacta tctctactgc tgctgctgct       60

gctactgctg ctgttgctac cgctgcctct gctgccaccg ccactactgc tgccagcgga      120

gccgctagga gtgagcatcc cctctccggg atacccagct ccgcggcgtc tcccgcgcgc      180

cctggcccca cacggacctg ccagccccag ggaacaaaag cggagcccgc tcgccctcta      240

ctgcagccgg aggatgagtc gagagggctg agcggagagt gtggtcctcg gcggctggag      300

ctatttcctt ggcttctctc catgacgatt cctgactcgt ggccccggca atcttgggaa      360

gacatcatcc agcttcttca gtccagaccc tgggcacccc ccttttgcca ggatcgtccc      420

cacccagcct ggacacattg actgaactgt tttctaggac actgcactca gcaagacatg      480

gtggtgagcc ctgactctca gtcttcatga ttgaagaact cttttgtaca acacaaagca      540

ctcaaaaaga gtgaatgaaa tgtgcagctc agagtgtcat ttctgaaggg aggagtcttt      600

ctcttggaga agagtcctca atgagcctgg ccgaggcccg ggatctgtgt gaagtggact      660

aaggattaag taggatgtca actgagacag aacttcaagt agctgtgaaa accagcgcca      720

agaaagactc cagaaagaaa ggtcaggatc gcagtgaagc cactttgata aagaggttta      780

aaggtgaagg ggtccggtac aaagccaaat tgatcgggat tgatgaagtt tccgcagctc      840

ggggagacaa gttatgtcaa gattccatga tgaaactcaa gggcgttgtt gctggcgctc      900

gttccaaagg agaacacaaa cagaaaatct ttttaaccat ctcctttgga ggaatcaaaa      960

tctttgatga gaagacaggg gcccttcagc atcatcatgc tgttcatgaa atatcctaca     1020

ttgcaaagga cattacagat caccgggcct ttggatatgt ttgtgggaag gaagggaatc     1080

acagatttgt ggccataaaa acagcccagg cggctgaacc tgttattctg gacttgagag     1140

atctctttca actcatttat gaattgaagc aaagagaaga attagaaaaa aaggcacaaa     1200

aggataagca gtgtgaacaa gctgtgtacc agacaatatt ggaagaggat gttgaagatc     1260

ctgtgtacca gtacattgtg tttgaggctg gacacgagcc aatccgtgat cccgaaacgg     1320

aagaaaacat ttatcaggtt cccaccagcc aaaagaagga aggtgtttat gatgtgccaa     1380

aaagtcaacc tgtaagtgct gtgacccaat tagaactttt tggggacatg tccacacccc     1440

ctgatataac ctctcccccc actcctgcaa ctccaggtga tgcctttatc ccatcttcat     1500

ctcagaccct tccagcgagt gcagatgtgt ttagttctgt acctttcggc actgctgctg     1560

taccctcagg ttacgttgca atgggcgctg tcctcccgtc cttctggggt cagcagcccc     1620

tcgtccaaca gcagatggtc atgggtgccc agccaccagt cgctcaggtg atgccggggg     1680

ctcagcccat cgcatggggc cagccgggtc tctttcctgc cactcagcag ccctggccaa     1740

ctgtggccgg gcagtttccg ccagccgcct tcatgcccac acaaactgtt atgcctttgc     1800

cagctgccat gttccaaggt cccctcaccc cccttgccac cgtcccaggc acgagtgact     1860

ccaccaggtc aagtccacag accgacaagc ccaggcagaa aatgggcaaa gaaacgttta     1920

aggatttcca gatggcccag cctccgcccg tgccctcccg caaacccgac cagccctccc     1980

tcacctgtac ctcagaggcc ttctccagtt acttcaacaa agtcggggtg gcacaggata     2040

cagacgactg tgatgacttt gacatctccc agttgaattt gacccctgtg acttctacca     2100

caccatcgac caactcacct ccaaccccag cccctagaca gagctctcca tccaaatcat     2160

ctgcatccca tgccagtgat cctaccacag atgacatctt tgaagagggc tttgaaagtc     2220

ccagcaaaag cgaagagcaa gaagctcctg atggatcaca ggcctcatcc aacagtgatc     2280

catttggtga gcccagtggg gagcccagtg gtgataatat aagtccacag gccggtagct     2340

agatagcgca ggtctgggag ccagagcctc tgtacgcgca gatcaacaga cctaagaaat     2400

agcatcgatg cgagctcgtg gtgggtgctc aagactggca tggacatcag catcacgaca     2460

ggctctcttg tattctttca cctcttccca caagaaattc atgattgccc aatggaactc     2520

gctcagaaga gggaactaag catttttggc aaccaatggc agatatctat ggcagcacac     2580


<210>  1255
<211>  4634
<212>  DNA
<213>  homo sapiens

<400>  1255
atctttgatc aatgtacttg ccagggagag cccaagtcct tcaaacctcc tccttttcac       60

cttcatcctt aactttgtgc tagagcgaga cccacacaac aacagccgac cctccccgcc      120

ccacccccac ccccaaacca gccctcgatc ccagcccccg gagaggactc gcatttcgac      180

ttgcgggaca cttttgtgcg ttcctctcca gagcgcctct cgtgctcgcc cctcttgcgc      240

tcgctcttta ttaccttcac ctccttttct cccccttctc tccctttctc cttctcgttc      300

tctcccggag ttgttgttgc ccccctcgct ccttctcccc ccttttttcc ccttcccctc      360

ccgggggtgt gtggcaactt ttcctctcgc ttctcctccg tctgtttccc cttatatgtg      420

accatggcag tgccggcggc tttgatccct ccgacccagc tggtcccccc tcaaccccca      480

atctccacgt ctgcttcctc ctctggcacc accacctcca cctcttcggc gacttcgtct      540

ccggctcctt ccatcggacc cccggcgtcc tctgggccaa ctctgttccg cccggagccc      600

atcgcttcgg cggcggcggc ggcggccaca gtcacctcta ccggcggcgg cggcggcggc      660

ggcggcagcg gaggcggcgg cggcagcagc ggcaacggag gcggcggtgg cggcggcggc      720

ggtggcagca actgcaaccc caacctggcg gccgcgagca acggcagcgg cggcggcggc      780

ggcggcatca gcgctggcgg cggcgtcgct tccagcaccc ccatcaacgc cagcaccggc      840

agcagcagca gcagcagtag cagcagcagc agcagcagca gtagtagcag cagcagcagt      900

agcagcagca gctgcggccc cctccccggg aaacccgtgt actcaacccc gtccccagtg      960

gaaaacaccc ctcagaataa tgagtgcaaa atggtggatc tgaggggggc caaagtggct     1020

tccttcacgg tggagggctg cgagctgatc tgcctgcccc aggctttcga cctgttcctg     1080

aagcacttgg tggggggctt gcatacggtc tacaccaagc tgaagcggct ggagatcacg     1140

ccggtggtgt gcaatgtgga acaagttcgc atcctgaggg gactgggcgc catccagcca     1200

ggagtgaacc gctgcaaact catctccagg aaggacttcg agaccctcta caatgactgc     1260

accaacgcaa gttctagacc tggaaggcct cctaagagga ctcaaagtgt cacctcccca     1320

gagaactctc acatcatgcc gcattctgtc cctggtctca tgtctcctgg gataattcca     1380

ccaacagatg agaccccgct ttctacacca accgcaagag acagccttga caaactctct     1440

ctaactgggc atggacaacc actgcctcca ggttttccat ctccttttct gtttcctgat     1500

ggactgtctt ccatcgagac tcttctgact aacatacagg ggctgttgaa agttgccata     1560

gataatgcca gagctcaaga gaaacaggtc caactggaaa aaactgagct gaagatggat     1620

tttttaaggg aaagagaact aagggaaaca cttgagaagc agttggctat ggaacaaaag     1680

aatagagcca tagttcaaaa gaggctaaag aaggagaaga aggcaaagag aaaattgcag     1740

gaagcacttg agtttgagac gaaacggcgt gaacaagcag aacagacgct aaaacaggca     1800

gcttcaacag atagtctcag ggtcttaaat gactctctga ccccagagat agaggctgac     1860

cgcagtggcg gcagaacaga tgctgaaagg acaatacaag atggaagact gtatttgaaa     1920

actactgtca tgtactgaat ctttcctgtt gaagaaatcc atgttataga aaagaacttt     1980

gcagtcagac attcgtcatg ggaaagttca gaaaaaaata aagtcctttt aagggaactt     2040

cctgaatttt gtgtattaat gttctttaaa agtttaagta ttctacaaaa aaaaaaaaag     2100

ttttctccat tgattttcac ctgtggttca taccagagac ctgagaatgt ttgtaaatgt     2160

acaagtatca aagttcttac agttaattac tgcaacttgc tgctggacaa ttgtatacag     2220

agttaaaggc aggtctgaat aagacctagc tttgtttttt tctaatggaa tgaaccattt     2280

tcctcttctg aaaattctgt atctgagcac atcaagagac tcttgtagca gtggttaccc     2340

agacttacag aattatgtcc tccagaaacc agcaagaaca cttggaatga acgaatgaac     2400

ttgtaggggg catagaggat tcttgaaaaa aaaaaatgca agagtgattt tctgttacat     2460

tcaatttcaa actctctaat tgtgggtttt ctcctgaaga attttttttc acatactttc     2520

caaaagacca acaaatggat gttgacaaca acccaatgaa ataacatttt gcatatctga     2580

aaagaagcat tgaatataag ccaaaagctt tcactgaagg tttttttttc ttaaaaataa     2640

aaaaaaatat ataagtgtaa catgttttca ttccaaactg gtagtggtat atagaattaa     2700

agataataat gttgcttctt attcaaactg ttggtcatat gtacagtata taaacataaa     2760

acacacaagg aaggtattat gtatgcagta gtatactaga gtttaggaaa atgaaaattt     2820

tagaaaatat gttttgtcac cctgttggtc agaaagatgt ctttctggtt ttaacgcatg     2880

caggcatgta aatatttgtc tggagtcaca gtattaatga atgagatctt aagcatctgg     2940

tgacatcaga actctgtgtc agccactttt atttgtatat tgaaccctag ctagtgcccc     3000

aagctgcact attgggaatg gattgtggct gaacagcaaa tcaaaacacc agaaatattt     3060

ttatatgtta acgtcatatt atgttaatgt tgctgaaaac aaaacctaac aaaccttgat     3120

gtaccagtcc aataccatgt agcgctgagt gataaagtta aaatgtgctg tgcttcccac     3180

ccttgtcaga gggaagggtg gctatgtgtt attttcactg tctttttgaa agttacagta     3240

tgtgttttca ctttcgtgca gataactgga agtaaagcgg caaacagtgc ttattacatg     3300

ctaaagttac cttctctttg ttttttgcat atctggaatt acacctttaa agactgatat     3360

gaatcagtac ggtcactata cattttatga tttttctgtc atcttaaaat tgtatgatcg     3420

taacattatt tattaccaca aaacagcaaa atcttcaatg tctaagaaaa ctagcttaaa     3480

atgtttaaat atagttctga ttgggtatta attacttgat taagaaaaaa ttaacattat     3540

agatactctg gcattacgct tctatacctt ttaggtcttc cttgcaatac tggaacataa     3600

ttcttttgtg tagctcacta ttagccagct aagttcatct ttttaatacc ataaaaaggt     3660

tatatgtaca gttcctattt tagcttgctt acaaagggag cattattttt atttaaagta     3720

ttgctagtaa atgatttgta gaaacttggt tttctaagca tagttcttcc ataaccacct     3780

tttgttgttt gagcacaagg gattcttttc ctagttctat gtgtttgttt ccctatatgc     3840

agtctttaaa ggattacaac acttaaaatt gaatggactt gtgtcaagct ttttgcatca     3900

tacatttttt gaaagatttt taaaaaagcc tacaacttac atatgtagta gaatcagcca     3960

ttgctctgct cctggcatag agtcacctgt ttgttatgtg gattaaatag ttttaaaata     4020

catatttgaa gacctttgag aatgctttag tgtttgattt gaaataaaag gaaattttag     4080

caaggattaa agaaaaaagc tatcagctgt atgttaagag agactcttac taacatgttg     4140

taaatattac aattcatgaa atgttattgt aagtctgtaa cttaattttt tccctgtttt     4200

agttatacag gttggtttgg aaatttgtgt tttggcataa acaagtaaaa tgtgcccatt     4260

ttatggtttc catgcttttg taatcctaaa aatattaatg tctagttgtt ctatattata     4320

accacatttg cgctctatgc aagcccttgg aacagaacat actcatcttc atgtaggacc     4380

tatgaaaatt gtctattttt atctatatat ttaaagtttt ctaaaaatga taaaaggtta     4440

ttacgaattt tgttgtacaa aatctgtaca aaaatctgtt tttacatcat aatgcaagaa     4500

ttggaaattt ttctatggta gcctagttat ttgagcctgg tttcaatgtg agaaccacgt     4560

ttactgttat tgtatttaat tttcttttcc ttttcaacaa tctcctaata aaactgtctg     4620

aaatctcaaa aaaa                                                       4634


<210>  1256
<211>  683
<212>  DNA
<213>  homo sapiens

<400>  1256
ctgcgcagat gaggggagac tcgtcaccag gcgtgcagtg ggcactgctg ggctccccca       60

tcccgtccta acccggaaca gccccgggca ggaggcgtgg aaagtcgagg gggtaaaccg      120

cgaatgtgcg ttgtgtaagc cacggcgcag ggtggggcgc gggcgggact tgggcgggcg      180

gggtgggctt ggccgagctg gcctccgggg caccgaccgc tataaggcca gtcggactgc      240

gacacagccc atcccctcga ccgctcgcgt cgcatttggc cgcctcccta ccgctccaag      300

cccagccctc agccatggca tgccccctgg atcaggccat tggcctcctc gtggccatct      360

tccacaagta ctccggcagg gagggtgaca agcacaccct gagcaagaag gagctgaagg      420

agctgatcca gaaggagctc accattggct cgaagctgca ggatgctgaa attgcaaggc      480

tgatggaaga cttggaccgg aacaaggacc aggaggtgaa cttccaggag tatgtcacct      540

tcctgggggc cttggctttg atctacaatg aagccctcaa gggctgaaaa taaataggga      600

agatggagac accctctggg ggtcctctct gagtcaaatc cagtggtggg taattgtaca      660

ataaattttt tttggtcaaa ttt                                              683


<210>  1257
<211>  2116
<212>  DNA
<213>  homo sapiens

<400>  1257
cggaccctcc cgcggccgac tggaggcccg gagcaggggc ggagtttccg gcggcagcgc       60

cactcgggcg tcgggtgacg ctaggcggac ggaccatcat gtgacacgga agtagctccg      120

aacaggaaga ggacgaaaaa aataaccgtc cgcgacgccg agacaaaccg gacccgcaac      180

caccatgaac agcaaaggtc aatatccaac acagccaacc taccctgtgc agcctcctgg      240

gaatccagta taccctcaga ccttgcatct tcctcaggct ccaccctata ccgatgctcc      300

acctgcctac tcagagctct atcgtccgag ctttgtgcac ccaggggctg ccacagtccc      360

caccatgtca gccgcaatcc ccatggctta ttatccagtc ggtcccatct atccacctgg      420

ctccacagtg ctggtggaag gagggtatga tgcaggtgcc agatttggag ctggggctac      480

tgctggcaac attcctcctc cacctcctgg atgccctccc aatgctgctc agcttgcagt      540

catgcaggga gccaacgtcc tcgtaactca gcggaagggg aacttcttca tgggtggttc      600

agatggtggc tacaccatct ggtgaggaac caaggccacc tctgtgccgg gaaagacatc      660

acataccttc agcacttctc acaatgtaac tgctttagtc atattaacct gaagttgcag      720

tttagacaca tgttgttggg gtgtctttct ggtgcccaaa ctttcaggca cttttcaaat      780

ttaataagga accatgtaat ggtagcagta cctccctaaa gcattttgag gtaggggagg      840

tatccattca taaaatgaat gtgggtgaag ccgccctaag gattttcctt taatttctct      900

ggagtaatac tgtaccatac tggtctttgc ttttagtaat aaaacatcaa attaggtttg      960

gagggaactt tgatcttcct aagaattaaa gttgccaaat tattctgatt ggtctttaat     1020

ctcctttaag tctttgatat atattacttg ttataaatgg aacgcattag ttgtctgcct     1080

tttcctttcc atcccttgcc ccacccatcc catctccaac cctagtcttc catttcctcc     1140

cgccagtctc cattgaatca atggtgcagg acagaaagcc agtcagacta atttccttct     1200

ttcctcgcac ttctccccac tcgtcatctt ttaactagtg tttcacaagg atcctctgaa     1260

accctctctg tgccccaagt acagatgcca ttacttctgc tttcgtatct cctcaggcaa     1320

aagtggaggg tgccttatgg gccctcctca taggttgtct ctgcatacac gaacctaacc     1380

caaatttgct ttggtgccag aaaaactgag ctatgtttga acaaagatgt cgtgcaaact     1440

gtactgtgaa caacagttgg tttaaaatat gaggggcaag gaggaggatg catttcaaaa     1500

gcttgattga tgtgttcaga gctaaattaa gaggagtttt cagatcaaaa actggttacc     1560

attttttgtc agagtgtctg atgcggccac tcattcggct ccccagaatt cctagactgg     1620

gttaataggg tcatattgtg aatgtctcac tacaaaatga cttgagtcca gtgaaatctc     1680

attagggttt aagaatattt cagggatcct taatgttttg atttttgttt tctgaaattg     1740

gattttattt tattttatct tataatttca gttcatctaa attgtgtgtt ctgtacatgt     1800

gatgtttgac tgtaccattg actgttatgg aagttcagcg ttgtatgtct ctctctacac     1860

tgtggtgcac ttaacttgtg gaatttttat actaaaaatg tagaataaag actattttga     1920

agatttgaat aaagtgatga agttgcatta cacctcactg caaggattct ttacttagct     1980

tgtttttaga tttcttctat atatatttta tttatatccc atctagaatt cagctaggtg     2040

ctgctgctgc tctgtttcct ttgatgacgc tttgaaataa aggcaggagt acaagcctaa     2100

aaaaaaaaaa aaaaaa                                                     2116


<210>  1258
<211>  5143
<212>  DNA
<213>  homo sapiens

<400>  1258
ttattctgcc ccagctgatg tttgagccag catgtcgcgg aggaagcaag cgaagcctca       60

acatttccaa tccgaccccg aagtggcctc gctcccccgg cgagatggag acacagaaaa      120

gggtcaaccg agtcgcccta ctaagagcaa ggatgcccac gtctgtggcc ggtgctgtgc      180

cgagttcttt gaattatcag atcttctgct ccacaagaag aactgtacta aaaatcaatt      240

agttttaatc gtaaatgaaa atccagcctc cccacccgaa accttctccc ccagcccccc      300

tcctgataat cctgatgaac aaatgaatga cacagttaac aaaacagatc aagtggactg      360

cagcgacctt tcagaacaca acggacttga cagggaagag tccatggagg tggaggcccc      420

ggttgctaac aaaagcggca gcggcacttc cagcggcagc cacagcagta ccgccccaag      480

cagcagcagc agcagcagca gcagcagcgg cggcggcggc agctcctcca caggtacctc      540

agcgatcaca acctctctac ctcaactcgg ggacctgaca acactgggca acttctccgt      600

aatcaacagc aacgtcatca tcgagaacct ccagagcacc aaggtggcgg tggcccagtt      660

ctcccaggaa gcgaggtgcg gcggggcctc tgggggcaag ctggccgtcc cagccctcat      720

ggaacaactc ctagctctgc agcagcagca gatccaccag ctgcaattga tcgaacagat      780

tcgtcaccaa atattgctgt tggcttctca gaatgcagac ttgccaacat cttctagtcc      840

ttctcaaggt actttacgaa catctgccaa ccccttgtcc acgctaagtt cccatttatc      900

tcagcagctg gcagcagcag ctggattggc acagagcctc gccagccaat ctgccagcat      960

tagtggtgtg aaacagctac ccccaatcca gctacctcag agcagttctg gcaacaccat     1020

cattccatcc aacagcggct cttctcccaa tatgaacata ttggcagcgg cagttaccac     1080

cccgtcctct gaaaaagtgg cttcaagtgc tggggcctcc catgtcagca acccagcggt     1140

ctcatcatcg tcctcaccag cttttgcaat aagcagttta ttaagtcctg cgtctaatcc     1200

acttctacct cagcaagcct ccgctaactc ggttttcccc agccctttgc ccaacatcgg     1260

aacaactgca gaggatttaa actccttgtc tgccttggcc cagcaaagaa aaagcaagcc     1320

accaaatgtc actgcctttg aagcgaaaag tacttccgat gaggcattct tcaaacacaa     1380

gtgcaggttc tgcgcgaagg tctttgggag tgacagtgcc ttgcagatcc acttgcgttc     1440

ccataccgga gagaggccat tcaagtgcaa catctgcggg aacaggttct ccaccaaggg     1500

gaatctgaaa gtccactttc agcgccacaa agagaaatac cctcatatcc agatgaaccc     1560

ctatcctgtg cctgagcatt tggacaatat ccccacgagt actggcatcc catatggcat     1620

gtccatccct ccagagaagc cagtcaccag ctggctagac accaaaccag tcctgcctac     1680

tctgaccact tcagtcggcc tgccgttgcc cccaaccctc ccaagcctca tacccttcat     1740

caagacggaa gagccagccc ccatccccat cagccattct gccaccagcc ccccaggctc     1800

agtcaaaagt gactccgggg gccctgagtc agccacaaga aacctaggtg ggctcccaga     1860

ggaagccgaa gggtccactc tgccaccctc tggtggcaaa agcgaagaga gtggcatggt     1920

caccaactca gtcccgacgg cgagcagtag cgtcctgagc tccccagcgg cagactgcgg     1980

ccccgcgggc agtgccacca ccttcaccaa ccctttgttg ccgctcatgt ccgagcagtt     2040

caaggccaag tttccttttg ggggactcct ggactcagct caggcatcag agacgtccaa     2100

gcttcagcaa ctggtagaaa acattgacaa gaaggccact gaccccaatg agtgcatcat     2160

ctgccaccgg gttctcagct gccagagcgc cttgaaaatg cactacagga cacacactgg     2220

ggagaggccc tttaagtgta agatctgtgg ccgggctttc accacgaaag ggaatcttaa     2280

aacccactac agtgtccatc gtgctatgcc cccgctcaga gtccagcatt cctgccccat     2340

ctgccagaag aagttcacga acgctgtggt cctgcagcag cacatccgaa tgcatatggg     2400

aggccagatc cccaacaccc cagtccccga cagctactct gagtccatgg agtctgacac     2460

aggttccttt gatgagaaaa attttgatga cctagacaac ttctctgatg aaaacatgga     2520

agactgtcct gagggcagca tccctgatac acctaagtct gcagacgcct cccaagacag     2580

cttatcctct tcgcctttgc ccctcgagat gtcgagcatc gctgctttgg aaaatcagat     2640

gaagatgatc aatgctggcc tggcagagca gctacaggcc agcctgaagt cagtggagaa     2700

tgggtccatc gagggggatg tcctgaccaa tgattcatcc tcagtgggtg gtgacatgga     2760

aagccaaagt gctggcagcc cagccatctc agagtctacc tcttccatgc aggctctgtc     2820

cccgtccaac agcacgcagg agttccacaa gtcacccagc attgaggaga aaccacagag     2880

agcggtccca agcgagtttg ccaatggttt gtctcccacc ccagtgaatg gtggggcttt     2940

ggatttgaca tctagtcacg cagagaaaat catcaaagaa gattctttgg ggatcctctt     3000

cccttttaga gaccggggta aatttaaaaa cactgcttgt gacatttgtg gcaaaacatt     3060

tgcttgtcag agtgccttgg acattcacta tagaagtcat accaaagaga gaccatttat     3120

ttgcacagtt tgcaatcgtg gcttttccac aaagggtaat ttgaagcagc acatgttgac     3180

acatcagatg cgagatctgc catcccagct ctttgagccc agttccaacc ttggccccaa     3240

tcagaactca gcggtgattc ccgccaactc gttgtcatct ctcatcaaga cagaggtcaa     3300

cggcttcgtg catgtttctc ctcaggacag taaggacacc cccaccagtc acgtcccgtc     3360

tgggcctctg tcttcctctg ccacatcccc agttctgctc cctgctctgc ccaggagaac     3420

tcccaagcag cactactgca acacatgtgg caaaaccttc tcctcatcga gtgccctgca     3480

gattcacgag agaactcaca ctggagagaa accctttgct tgcactattt gtggaagagc     3540

tttcacgact aaaggcaatc ttaaggtaca catgggcact cacatgtgga atagcacccc     3600

tgcacgacgg ggtcggcggc tctctgtgga tggccccatg acatttctag gaggcaatcc     3660

cgtcaagttc ccagaaatgt tccagaagga tttggcggca agatcaggaa gtggggatcc     3720

ttccagcttc tggaatcagt atgcagcagc gctctccaac gggctggcga tgaaggccaa     3780

cgagatctcc gtcattcaga acggtggcat ccctccaatt cctggaagcc tcggcagtgg     3840

gaacagctca cctgttagtg ggctgacggg aaacctggag aggctccaga actcagagcc     3900

caatgctccc ctggccggcc tggagaaaat ggcaagcagt gagaacggaa ccaacttccg     3960

cttcacccgc ttcgtggagg acagcaagga gatcgtcacg agttaaagca gctcgggctg     4020

gagacatagc attcattcct gttcagaatg cgacctatgg tggcctccta ctccttgccc     4080

cccaccccgc cccgcccctt ccttctgttc cccagatcta tgaactacaa cattatgaag     4140

acattctttt gtaccttgtt caactttaga gttctaagaa agcttattta ttagcgatat     4200

aaccttgctt tgcaaacaga atgcaagcgt taactttggt cttctgtatt ttggactaaa     4260

tactaattga ctagagtgct gtaaacttgc tgtaacattt atggcaattg caagttgccc     4320

tgctaggcag ttgtaatctg gcattaactt attttctata tccagtttaa tatgaatctg     4380

gtgttgatgc aatgcctcag tgatgcatta gatctctaat aaagtctgta tatacatgta     4440

cactttgatc ctgctggaaa attttatcag caaacacatt gtctaatctt tcaaaacaga     4500

tttaaggaaa ggactgaaag tacagactga acagtgtggt tctttgaaag gtttggtttt     4560

ttaattttta ttctaaaatt caaccttttt ttttgtcgat ttaaccattt ccattttgaa     4620

ctgctatttg tattgtgctt tttacttgag tcgtcttcaa tgttaataag tttctgtaca     4680

gtaataagca cgcagaattc tttagagaaa aagaaaacaa gcgttgtttt ggtagttgaa     4740

actgagacgt aacattttgc cttgtaggta tattcacgat agaaaatgtg tgctggaatt     4800

tcacaatgct gctaagtata gcatcttgaa caaccttcag tggagaaaat gtagatgctc     4860

ttgtatatac aataagaaat atcactttca ttcaaatgta catatgttcc ttacaagagc     4920

aaatgcttct tcttgatcaa gagagcaggt atagtgtttg tttattttgt cttaggtatg     4980

gaagaaaaaa attggactgt tacatgcact ttcttggaaa gttgaaagga aagggggggt     5040

ccaatttctt taacatttaa tacttactaa caacagagat actgtaattt tactcaagta     5100

atcaaataca ttttttttgc aacagataaa acaaaatact gtg                       5143


<210>  1259
<211>  1921
<212>  DNA
<213>  homo sapiens

<400>  1259
agcttctgcc aagggtgggg gcccacgcgg aggcgatccg ctcgttcctc ccagggccat       60

ggggcgacga ggagagccct ggcctccccg cgacccgcac tgcgacctgg gccagacgcg      120

ccaccttccc cggtcgcggt ttgcttctct ttaaaatgag gacagctcct cccttggggg      180

ctgtggtgac aggtgaaatg agaacgcact gaagacagct cttggtccaa agccccgcac      240

acagggcatg gtctagtggc ccagtcagga cgcggaaaca ctccctggag gttctgaccc      300

actccctctc agcctccgcc tggtctctgg gttggctgtt ccagctccaa agagaaggag      360

gaaccttttc cttctgcagc ccctccccac cagcctcatt ccttagctgg ggtcagacct      420

ggggtcctca ctgcagctgg cctctggcag cgttctcagg ctagccctcc ctgctgaaaa      480

gagaaccgtg tgggactcac aggtgtagtc gccgccgcca gccgccatgg gcaaacagaa      540

cagcaagctg cggcccgagg tgctgcagga cctgcgggag aacacggagt tcaccgacca      600

cgagctgcag gagtggtaca agggcttcct caaggactgc cccaccggcc acctgaccgt      660

ggacgagttc aagaagatct acgccaactt cttcccctac ggcgacgctt ccaagttcgc      720

cgagcacgtc ttccgcacct tcgacaccaa cggcgacggc accatcgact tccgggagtt      780

catcattgcg ctgagcgtga cctcgcgggg caagctggag cagaagctca agtgggcctt      840

cagcatgtac gacctggacg gcaacggcta catcagccgc agcgagatgc tggagatcgt      900

gcaggccatc tacaagatgg tgtcgtctgt gatgaagatg ccggaggatg agtccacccc      960

ggagaagcgc acagacaaga tcttcaggca gatggacacc aacaatgacg gcaaactgtc     1020

cttggaagaa ttcatcagag gtgccaagag cgacccctcc atcgtccgcc tgctgcagtg     1080

cgaccccagc agtgccagtc agttctgagc gagcggcccc tggacagttg cagagaaaca     1140

caggcttgtc gtgccgttta agctttgctt gcaagagtgg atgccccgca atcgttcctg     1200

ctctcccggg ccccgggcct ggggcatgcg ttgcacctgc ccagcccggt ggctgcgcct     1260

ccctcctcca cctgaccaac gcgacattcc tcccctcacg cctggcccgg tcccttccag     1320

ggcaactccc agggatgtgg tgacatgcag ggttcaagtg ttcttggttc caggcacctc     1380

ccggctcacg gggagctcag aggtccatgc cgaggagacc aggcaggacc tcccgaggct     1440

gcgccccggc cggcccatgc gttttgtgat cccaagtgac tctgtgggaa gggtggggac     1500

gaggcgtcgg gagggtatac agggagcccc tcccgtgcat ggctgccccc ccgttcattt     1560

tctccaccac agccgcttgc acgtatagat actgtggtcc cctttctttt aatatataaa     1620

ttatgtatgg tgaagtggag tgtattgtgt aggtcccgta tttaatgcct ctgactgcct     1680

ttgaagcgca gccctctgtg gcccgcagcc ccctgagcct ggctgttgtg tggtatttat     1740

gctctctttg tctgcctgtt tctaaggaaa tgcatgtgtg ccctgagccg tgatgatcct     1800

cccatccgtg ttgtgagcac aggcatttgt gtctggtctg tcctccctgt tgattggtct     1860

ggcatttccg gtattaaaat gataaaataa atggcatttt ctgaaaaaaa aaaaaaaaaa     1920

a                                                                     1921


<210>  1260
<211>  1921
<212>  DNA
<213>  homo sapiens

<400>  1260
agcttctgcc aagggtgggg gcccacgcgg aggcgatccg ctcgttcctc ccagggccat       60

ggggcgacga ggagagccct ggcctccccg cgacccgcac tgcgacctgg gccagacgcg      120

ccaccttccc cggtcgcggt ttgcttctct ttaaaatgag gacagctcct cccttggggg      180

ctgtggtgac aggtgaaatg agaacgcact gaagacagct cttggtccaa agccccgcac      240

acagggcatg gtctagtggc ccagtcagga cgcggaaaca ctccctggag gttctgaccc      300

actccctctc agcctccgcc tggtctctgg gttggctgtt ccagctccaa agagaaggag      360

gaaccttttc cttctgcagc ccctccccac cagcctcatt ccttagctgg ggtcagacct      420

ggggtcctca ctgcagctgg cctctggcag cgttctcagg ctagccctcc ctgctgaaaa      480

gagaaccgtg tgggactcac aggtgtagtc gccgccgcca gccgccatgg gcaaacagaa      540

cagcaagctg cggcccgagg tgctgcagga cctgcgggag aacacggagt tcaccgacca      600

cgagctgcag gagtggtaca agggcttcct caaggactgc cccaccggcc acctgaccgt      660

ggacgagttc aagaagatct acgccaactt cttcccctac ggcgacgctt ccaagttcgc      720

cgagcacgtc ttccgcacct tcgacaccaa cggcgacggc accatcgact tccgggagtt      780

catcattgcg ctgagcgtga cctcgcgggg caagctggag cagaagctca agtgggcctt      840

cagcatgtac gacctggacg gcaacggcta catcagccgc agcgagatgc tggagatcgt      900

gcaggccatc tacaagatgg tgtcgtctgt gatgaagatg ccggaggatg agtccacccc      960

ggagaagcgc acagacaaga tcttcaggca gatggacacc aacaatgacg gcaaactgtc     1020

cttggaagaa ttcatcagag gtgccaagag cgacccctcc atcgtccgcc tgctgcagtg     1080

cgaccccagc agtgccagtc agttctgagc gagcggcccc tggacagttg cagagaaaca     1140

caggcttgtc gtgccgttta agctttgctt gcaagagtgg atgccccgca atcgttcctg     1200

ctctcccggg ccccgggcct ggggcatgcg ttgcacctgc ccagcccggt ggctgcgcct     1260

ccctcctcca cctgaccaac gcgacattcc tcccctcacg cctggcccgg tcccttccag     1320

ggcaactccc agggatgtgg tgacatgcag ggttcaagtg ttcttggttc caggcacctc     1380

ccggctcacg gggagctcag aggtccatgc cgaggagacc aggcaggacc tcccgaggct     1440

gcgccccggc cggcccatgc gttttgtgat cccaagtgac tctgtgggaa gggtggggac     1500

gaggcgtcgg gagggtatac agggagcccc tcccgtgcat ggctgccccc ccgttcattt     1560

tctccaccac agccgcttgc acgtatagat actgtggtcc cctttctttt aatatataaa     1620

ttatgtatgg tgaagtggag tgtattgtgt aggtcccgta tttaatgcct ctgactgcct     1680

ttgaagcgca gccctctgtg gcccgcagcc ccctgagcct ggctgttgtg tggtatttat     1740

gctctctttg tctgcctgtt tctaaggaaa tgcatgtgtg ccctgagccg tgatgatcct     1800

cccatccgtg ttgtgagcac aggcatttgt gtctggtctg tcctccctgt tgattggtct     1860

ggcatttccg gtattaaaat gataaaataa atggcatttt ctgaaaaaaa aaaaaaaaaa     1920

a                                                                     1921


<210>  1261
<211>  4143
<212>  DNA
<213>  homo sapiens

<400>  1261
ccgcgggcgg ggccggctgg cgttcacgtg acccggcgtc attggctcgc tcgcggaagt       60

agtcctacat tcgcggtcag cgcggggtct ccgggcgccc tgcagggcgg gcaggctgtg      120

ccatcccgcc ggacgtcggg atggtgcagc tgtacaacct gcacccgttc gggtcgcagc      180

aggtggtgcc ctgcaagctg gagccggacc ggttctgtgg cggggggcgt gacgcgcttt      240

tcgtggcggc gggctgcaag gtggaggcgt tcgcggtggc cggccaggag ctgtgccagc      300

cgcggtgcgc cttctccacg ctgggccggg tgttgcgcct ggcctacagc gaggctggag      360

attatttggt agcaattgaa gagaaaaaca aagctacatt tctacgtgct tatgtgaact      420

ggagaaataa aaggactgaa aactctcgtg tgtgtatccg aatgattggg cataatgtgg      480

agggaccatt cagcaaagcc ttcagagacc agatgtacat tattgaaatg ccgctttcgg      540

aggccccctt gtgcatttcc tgttgccctg tgaaaggaga ccttctcgtt ggctgcacaa      600

ataaattagt cttatttagt ttgaagtacc agatcattaa tgaggaattc tcactattgg      660

actttgaacg ttctttaatt atacacatag ataatatcac tcctgttgag gtttcttttt      720

gtgttggata tgttgctgtc atgtcagact tagaagtctt aatcgtaaaa ctggagtcag      780

gccctaaaaa tggagagaga gttcaccacc atccacataa gaccaacaat cgaataagac      840

ggacagaaga aggcatcagt aatgaaattt cacagcttga gtcagatgat tttgtcatct      900

gccagaagcc cctggaactt cttggtgaaa aaagtgaaca gtctggatta tctgttacac      960

tggagtctac gggattagct gatgaaaaaa gaaaatattc ccactttcag cacctgctct     1020

atagacgttt tgctcctgat atttcgtcct atgtcttgtc tgatgacatc aagctacatt     1080

ccctccagct gctacccatt taccagaccg gttctcttac atctgatgga aaaaatttgt     1140

ctcaggaaaa agaattgctg agtctctttt gctttttctc cttacctcat gtgggctatc     1200

tctacatggt tgtcaaatct gttgaattga tgtcagtcta ccagtatcct gaaaagtctc     1260

agcaggcagt actcacgcca caatttttgc acgtcattac aagtaacaac ctgcagtgtt     1320

tcactgtgcg gtgcagtgcg gcggcagctc gtgaggagga cccgtacatg gacaccaccc     1380

tgaaggcttg cccacctgtc agtatggatg tctgtgcttt aagaatacag cttttcatag     1440

gcttgaaagc catctgtcac tttaaaaacc acatcatact tttgactaaa gcagaacctg     1500

aagccattcc agagagaaga cagtcaccca agaggcttct ttcgagaaaa gataccagtg     1560

ttaaaatcaa aatacctcct gtagctgagg ctgggtggaa tttgtatatt gtgaatacga     1620

tctcaccagt gcagctgtac aaagagatgg tagactatag caatacctat aagactgtca     1680

aaacccagag ctgcattcac cttctcagtg aggctcatct gttagtgcga gctgccctga     1740

tggatgccag tcagctggaa cctggagaga aggcagagct tttggaagca tttaaggaaa     1800

gctgtgggca ccttggggac tgttacagca ggcttgactc ccagcattct catctcacct     1860

tgccatacta taagatgtct ggtttgtcta tggctgaagt tctggcccgc acggactgga     1920

cagtagagga tggattacag aaatacgaga gaggattaat cttttacatt aatcattcac     1980

tttatgaaaa cctggatgaa gaattaaatg aagaattagc agcaaaagtg gttcagatgt     2040

tttatgtggc tgagccaaag caagtgcccc atattctctg tagtccttct atgaagaata     2100

ttaatccttt aactgccatg agctatctaa ggaagctgga tacttctggg ttttcatcga     2160

tcttagtgac attgaccaag gcagcagtgg ctctgaaaat gggagatctt gacatgcaca     2220

gaaatgaaat gaaaagccat tcagagatga agttggtatg tggcttcatt ctggaacctc     2280

ggctgttgat tcaacagaga aagggacaga ttgttccaac cgagcttgca cttcacttga     2340

aggaaactca gcctggattg cttgtggctt cagttctggg cttgcagaag aacaacaaaa     2400

ttggaattga agaagcagat tcctttttta aggtgctttg tgctaaggat gaagatacaa     2460

ttcctcagct cttggtagac ttttgggaag ctcagctagt ggcatgtctc ccagatgtgg     2520

tacttcagga actctttttc aaactcacat cacagtacat ctggagattg tctaagaggc     2580

agcctcctga caccacacca ttgcgaacat cggaggatct gataaatgcc tgtagtcatt     2640

atggcttaat ttatccatgg gttcacgtcg taatatcatc tgattcttta gctgataaaa     2700

attatacaga agatctttca aaattacagt ctcttatatg tggtccttca tttgacatag     2760

cttccattat tccgttcttg gagccacttt cagaagacac tattgccggc ctcagtgtcc     2820

atgttctgtg tcgtacacgc ttgaaagagt atgaacagtg catagacata ctgttagaga     2880

gatgcccgga ggcagtcatt ccatatgcta atcatgaact gaaagaagag aaccggactc     2940

tgtggtggaa aaaactgttg cctgaacttt gtcagagaat aaaatgtggt ggagagaagt     3000

atcaactcta cctgtcatca ttaaaagaaa cattgtcaat tgttgctgtg gaactagaac     3060

tgaaggattt catgaatgtt ctcccagaag atggtactgc aacatttttc ttgccatatc     3120

ttctctattg cagtcgaaag aaaccattga cttaaaggta tcatttgaaa aataccataa     3180

tggcatttga gactgaattt ctaaaaattg aatgccaaag tacaagtaga ggagtttttt     3240

attttatata tcacacacac acacacacac acacacacac acacacacat atatgataca     3300

aatgctttca ggctgcttac cttaccgtgt agtggtaact attcacttct taatttatga     3360

cctcaatcaa tttaattgtc tagaatgtaa aaagtcttta agacataaga attcctcaaa     3420

gaagccatac attttttaag gtggggattg acttttattc caaggaacaa catcagttca     3480

ctgttgttgg agacatgaca atcattttca tcccaagaac actttaagga aacattttac     3540

aagtatgctt gaaagaatgt cactaactgg tccagaattt tatcttcttg atttttccag     3600

atttctctat gtttttgaga aagatgttaa tgttttgcca tggtaaaaga tttcaaacct     3660

catttttttt gttccttttc ttgttacttt taagaaaact catgctctgt ttctctgaat     3720

caaatgaagt agaagtttac aaagctaact ttcttcttgt ctagctatta acatgatttg     3780

tcaaatgcat gtttttttca gccaaagcct tgtttccatt tttgttgatg tgtactcttg     3840

ctcttttagc tagagtgtat gtgaaaataa agaaatacat cattgtattc acaaccatgt     3900

gtcttcattt ataacttttt gtttaaaaaa tttttagttc aagtttagtt cattgatatt     3960

atcctctgaa tgcagttaag gctgggcaga aattctactc atgtgacatc tgccacaggt     4020

ctattttgaa gcttttcttc taatggcaat gtttgtcctt accaggattt aatctataga     4080

attgtctctc aactctgctt ttctccagtt ccagataacg tccttaagaa aaaaaaaaaa     4140

aaa                                                                   4143


<210>  1262
<211>  4143
<212>  DNA
<213>  homo sapiens

<400>  1262
ccgcgggcgg ggccggctgg cgttcacgtg acccggcgtc attggctcgc tcgcggaagt       60

agtcctacat tcgcggtcag cgcggggtct ccgggcgccc tgcagggcgg gcaggctgtg      120

ccatcccgcc ggacgtcggg atggtgcagc tgtacaacct gcacccgttc gggtcgcagc      180

aggtggtgcc ctgcaagctg gagccggacc ggttctgtgg cggggggcgt gacgcgcttt      240

tcgtggcggc gggctgcaag gtggaggcgt tcgcggtggc cggccaggag ctgtgccagc      300

cgcggtgcgc cttctccacg ctgggccggg tgttgcgcct ggcctacagc gaggctggag      360

attatttggt agcaattgaa gagaaaaaca aagctacatt tctacgtgct tatgtgaact      420

ggagaaataa aaggactgaa aactctcgtg tgtgtatccg aatgattggg cataatgtgg      480

agggaccatt cagcaaagcc ttcagagacc agatgtacat tattgaaatg ccgctttcgg      540

aggccccctt gtgcatttcc tgttgccctg tgaaaggaga ccttctcgtt ggctgcacaa      600

ataaattagt cttatttagt ttgaagtacc agatcattaa tgaggaattc tcactattgg      660

actttgaacg ttctttaatt atacacatag ataatatcac tcctgttgag gtttcttttt      720

gtgttggata tgttgctgtc atgtcagact tagaagtctt aatcgtaaaa ctggagtcag      780

gccctaaaaa tggagagaga gttcaccacc atccacataa gaccaacaat cgaataagac      840

ggacagaaga aggcatcagt aatgaaattt cacagcttga gtcagatgat tttgtcatct      900

gccagaagcc cctggaactt cttggtgaaa aaagtgaaca gtctggatta tctgttacac      960

tggagtctac gggattagct gatgaaaaaa gaaaatattc ccactttcag cacctgctct     1020

atagacgttt tgctcctgat atttcgtcct atgtcttgtc tgatgacatc aagctacatt     1080

ccctccagct gctacccatt taccagaccg gttctcttac atctgatgga aaaaatttgt     1140

ctcaggaaaa agaattgctg agtctctttt gctttttctc cttacctcat gtgggctatc     1200

tctacatggt tgtcaaatct gttgaattga tgtcagtcta ccagtatcct gaaaagtctc     1260

agcaggcagt actcacgcca caatttttgc acgtcattac aagtaacaac ctgcagtgtt     1320

tcactgtgcg gtgcagtgcg gcggcagctc gtgaggagga cccgtacatg gacaccaccc     1380

tgaaggcttg cccacctgtc agtatggatg tctgtgcttt aagaatacag cttttcatag     1440

gcttgaaagc catctgtcac tttaaaaacc acatcatact tttgactaaa gcagaacctg     1500

aagccattcc agagagaaga cagtcaccca agaggcttct ttcgagaaaa gataccagtg     1560

ttaaaatcaa aatacctcct gtagctgagg ctgggtggaa tttgtatatt gtgaatacga     1620

tctcaccagt gcagctgtac aaagagatgg tagactatag caatacctat aagactgtca     1680

aaacccagag ctgcattcac cttctcagtg aggctcatct gttagtgcga gctgccctga     1740

tggatgccag tcagctggaa cctggagaga aggcagagct tttggaagca tttaaggaaa     1800

gctgtgggca ccttggggac tgttacagca ggcttgactc ccagcattct catctcacct     1860

tgccatacta taagatgtct ggtttgtcta tggctgaagt tctggcccgc acggactgga     1920

cagtagagga tggattacag aaatacgaga gaggattaat cttttacatt aatcattcac     1980

tttatgaaaa cctggatgaa gaattaaatg aagaattagc agcaaaagtg gttcagatgt     2040

tttatgtggc tgagccaaag caagtgcccc atattctctg tagtccttct atgaagaata     2100

ttaatccttt aactgccatg agctatctaa ggaagctgga tacttctggg ttttcatcga     2160

tcttagtgac attgaccaag gcagcagtgg ctctgaaaat gggagatctt gacatgcaca     2220

gaaatgaaat gaaaagccat tcagagatga agttggtatg tggcttcatt ctggaacctc     2280

ggctgttgat tcaacagaga aagggacaga ttgttccaac cgagcttgca cttcacttga     2340

aggaaactca gcctggattg cttgtggctt cagttctggg cttgcagaag aacaacaaaa     2400

ttggaattga agaagcagat tcctttttta aggtgctttg tgctaaggat gaagatacaa     2460

ttcctcagct cttggtagac ttttgggaag ctcagctagt ggcatgtctc ccagatgtgg     2520

tacttcagga actctttttc aaactcacat cacagtacat ctggagattg tctaagaggc     2580

agcctcctga caccacacca ttgcgaacat cggaggatct gataaatgcc tgtagtcatt     2640

atggcttaat ttatccatgg gttcacgtcg taatatcatc tgattcttta gctgataaaa     2700

attatacaga agatctttca aaattacagt ctcttatatg tggtccttca tttgacatag     2760

cttccattat tccgttcttg gagccacttt cagaagacac tattgccggc ctcagtgtcc     2820

atgttctgtg tcgtacacgc ttgaaagagt atgaacagtg catagacata ctgttagaga     2880

gatgcccgga ggcagtcatt ccatatgcta atcatgaact gaaagaagag aaccggactc     2940

tgtggtggaa aaaactgttg cctgaacttt gtcagagaat aaaatgtggt ggagagaagt     3000

atcaactcta cctgtcatca ttaaaagaaa cattgtcaat tgttgctgtg gaactagaac     3060

tgaaggattt catgaatgtt ctcccagaag atggtactgc aacatttttc ttgccatatc     3120

ttctctattg cagtcgaaag aaaccattga cttaaaggta tcatttgaaa aataccataa     3180

tggcatttga gactgaattt ctaaaaattg aatgccaaag tacaagtaga ggagtttttt     3240

attttatata tcacacacac acacacacac acacacacac acacacacat atatgataca     3300

aatgctttca ggctgcttac cttaccgtgt agtggtaact attcacttct taatttatga     3360

cctcaatcaa tttaattgtc tagaatgtaa aaagtcttta agacataaga attcctcaaa     3420

gaagccatac attttttaag gtggggattg acttttattc caaggaacaa catcagttca     3480

ctgttgttgg agacatgaca atcattttca tcccaagaac actttaagga aacattttac     3540

aagtatgctt gaaagaatgt cactaactgg tccagaattt tatcttcttg atttttccag     3600

atttctctat gtttttgaga aagatgttaa tgttttgcca tggtaaaaga tttcaaacct     3660

catttttttt gttccttttc ttgttacttt taagaaaact catgctctgt ttctctgaat     3720

caaatgaagt agaagtttac aaagctaact ttcttcttgt ctagctatta acatgatttg     3780

tcaaatgcat gtttttttca gccaaagcct tgtttccatt tttgttgatg tgtactcttg     3840

ctcttttagc tagagtgtat gtgaaaataa agaaatacat cattgtattc acaaccatgt     3900

gtcttcattt ataacttttt gtttaaaaaa tttttagttc aagtttagtt cattgatatt     3960

atcctctgaa tgcagttaag gctgggcaga aattctactc atgtgacatc tgccacaggt     4020

ctattttgaa gcttttcttc taatggcaat gtttgtcctt accaggattt aatctataga     4080

attgtctctc aactctgctt ttctccagtt ccagataacg tccttaagaa aaaaaaaaaa     4140

aaa                                                                   4143


<210>  1263
<211>  6770
<212>  DNA
<213>  homo sapiens

<400>  1263
ggaggggcgc gcggccgcga gcaaaggagg gagggaagga aggaagagag ggaggcgggc       60

aagcaggcgg gcgcgggggt cggggactga ggcagtagag ggaggcgaga gcccggcagc      120

cgcttcgcgc tgtttgctgc gcgggctttt ggagggggcg gccgtttagt cggctgagga      180

gaagcggaca ccagcggcgt tggtgatagc gcctggggga gggggactgg agaggcgaga      240

aggggggtcg ctgcggtggt tctctcgctg tcgctctctc tttgcctcgc tcccggctcg      300

gcgggctcct cccggcgtct ctctcgcctc cggggtcccg ctccccgccc cccgcggtat      360

gtcttgatcc cgagcagcgg gtttcatggg gctcctcagg attatgatgc cgcccaagtt      420

gcagctgctg gcggtggtgg ccttcgcggt ggcgatgctc ttcttggaaa accagatcca      480

gaaactggag gagtcccgct cgaagctaga aagggctatt gcaagacacg aagtccgaga      540

aattgagcag cgacatacaa tggatggccc tcggcaagat gccactttag atgaggaaga      600

ggacatggtg atcatttata acagagttcc caaaacggca agcacttcat ttaccaatat      660

cgcctatgac ctgtgtgcaa agaataaata ccatgtcctt catatcaaca ctaccaaaaa      720

taatccagtg atgtcattgc aagatcaggt gcgctttgta aagaatataa cttcctggaa      780

agagatgaaa ccaggatttt atcatggaca cgtttcttac ttggattttg caaaatttgg      840

tgtgaagaag aaaccaattt acattaatgt cataagggat cctattgaga ggctagtttc      900

ttattattac tttctgagat ttggagatga ttatagacca gggttacgga gacgaaaaca      960

aggagacaaa aagacctttg atgaatgtgt agcagaaggt ggctcagact gtgctccaga     1020

gaagctctgg cttcaaatcc cgttcttctg tggccatagc tccgaatgct ggaatgtggg     1080

aagcaggtgg gctatggatc aagccaagta taacctaatt aatgaatatt ttctggtggg     1140

agttactgaa gaacttgaag attttatcat gttattggag gcagcattgc cccggttttt     1200

caggggtgct actgaactct atcgcacagg aaagaaatct catcttagga aaaccacaga     1260

gaagaaactc cccactaaac aaaccattgc aaaactacag caatctgata tttggaaaat     1320

ggagaatgag ttctatgaat ttgcactaga gcagttccaa ttcatcagag cccatgccgt     1380

tcgagaaaaa gatggagacc tctacatcct cgcacaaaac tttttctatg aaaagattta     1440

ccctaagtcg aactgagtat aaggtgtgac tattggattc ttgaactaaa atttgaccct     1500

gtcttcacct ttgttctcag ctccacagtc tggattgctg acagtaggtg tatatgacaa     1560

tttgtattga gccaaattag gaaacagaca gtaacgtcaa ggaagtagat actggctggc     1620

attgtcagtg ttctaagttt caggcatttt tatttttcct ggctaaacgt tggtgaaagt     1680

tataacctcc tgcctgggag aaaatataca tcacctaaaa tgaacttatg gcaggtctaa     1740

tcaaaaggct aaatacaatt tcagaaaagg ttctgatact cttgtttttg ataaagcatt     1800

ttttcaacta accatgaatt aagatgagtc catttgcctc ttctgccttc actgagggtt     1860

tgggttatac acctctactg aattgtgtta ataactgttt ggcagtgtgt actttgtttt     1920

tgtgagtcat gtctcatgaa atttattgga atgtttaatc atatttgcta agaaatgttt     1980

ctgctgtagt tggatttgcc catatttatg taggtggttt taatttttta aatggtgatt     2040

agtgttaaaa atcaatttaa atcatgacta atatggtaaa aagataaagc atcaaagcag     2100

tatttctcat tcctgcctcc tcaatatcta atactgggaa gatacttcaa agaatattga     2160

gattgtctga agttttagtt aagattttca cacattaata tcaaaaaagt aagtttagta     2220

tttgtttctc catgggttat ttgtaaagct gtaaactgag atatcggtga ctccgtatta     2280

tgactccatt agtgagctgt ggtatgggta ggattttcct acttcttctg tacttttacc     2340

tgtagactat ttttactaag gtgctttata atgtgtttta aagcattgca tttacaaaac     2400

aaggaaaatg ctgtaaatat tgcatatttt atgtatttgg accaaaaggt tacaagtaat     2460

tagacaaaag tggttttgca ccaattttat gtcaagtaaa accatcagac ctactgttct     2520

tgtatttctc atttaacttt actgttaaga catcactgaa atgaacttca gtaagctttc     2580

aattttgata cacagttcat tattcataac ttgaggcagt aattacagtg gaatgagtac     2640

tggacaagga gtcaaaaaac ttgatttcag gtcctagctc tagcacttac agctgtgtga     2700

tcttgggcaa gtcacttaac ctctctttgc ctcaatttcc tcatcttgaa atgaggataa     2760

taatacctgc tgtacctacc tcacagggct gttgtgagga ttaaatgaga tggcatgtga     2820

aagcactttg aaaattgtaa agcgctatgt aaatgtaagg tattatagaa acatctttaa     2880

catatagttt cataccattc attttttaac aaagaaaggg aaaagtctgc ttgtaagctg     2940

gttgaaaaag ttaatcttga tataaatttg tgtttgataa atatcctctc agtgttttat     3000

cttccatgtt tcaacaacta ttgaaatatg aaatgcctgt gaactcttaa agcttcatga     3060

gcagctgctt gagttcagga agttcactgt tagaaatagg ctttgttagc tgactagggt     3120

cagggaaact tttctcttca aatttgaaag ctgtttctgt tttcatttta cattattatt     3180

cagaaatggt agctattcta tacctatggt ttaagtaaat atttctgaat aaggcttcac     3240

catactgtaa gcattttagg tagattgcct taaaggttat gggagggcat gagggaacac     3300

ttcttatgag aaaacattta taaacaaaag aaacatttat aaactaaaga aaaactaaaa     3360

gaatgacaga acaatcatct tagcaccctt tcctcacaat aatataaaaa tattaaaaga     3420

acataggcag gcttttttta aatttggctt ttttctttcc ttttttcaaa ttgactttta     3480

taggtatttc ctgaaagtgt atacaaatta tttcctcgcc caaaataaag caccacttca     3540

aggtgtggtt tgacattaca tgctaatgaa caaacccagt atgcaagtta ttcttgcacc     3600

acatgctcaa atcttcttga ggtgcattaa ctcttttagg taactagagc agtacttggt     3660

gaactagatc aggaggtcag taaactttct gtggaagggc cagagagtaa atattttagg     3720

ctttgcagcc catacggtct ctgtcacagc tagtcaaccc tgccatttta ccacaaaagc     3780

agcaatagac attatgtaaa caaatgagca cagttatgtt ccaataaaac tttatttaca     3840

aaaacagatg acatcccaga tgcagaccat gggcaaccaa ccattgcact ggccaaatca     3900

ttatttatgg agaaatcctc tttgtgtctc tactctagat gcctaaaaga gtttatatac     3960

ttctaaaagc tcctaactta tatccaaaga attgctttct gattcgtgta gtctctccca     4020

cagattcata aacttttatg acttatattg tttccaggtg ggcatggttt atttcccagt     4080

ttaacagttc agaatagggg catttatttt atcatatttt agggtgggtt aggagtatcc     4140

tttctggaga ctgagaaagg ggtgtattta attccatcag gtccagtaca gtactaggag     4200

tcataatact ttataatcaa ttaaataaat agaaccactg agacaataat gtattttttt     4260

aaagtggcaa atgtggtttt cttttttcag cctttgcgct ttttcagtat tttgaccata     4320

gggagataat ttttttataa tacaaaagta accacttgga attttaaaga taatgttatg     4380

tgtgtatgtg aaatatatat acatatatat atatatgttt atttcctaaa agaagaaaag     4440

atacctttct gttcaacttg tatcaactcc tcttttctaa ttgctgtgaa atggcaactg     4500

ttgataaatt attgtgattg ttttaaaatc taatgggaag taaaatatat tttgatttta     4560

cccagcttaa tctgtaaagt agcacttaaa tatatctgat agcaacactt aagatattgc     4620

atggggatta ctttcctatc atccatatgc atttgtgcaa cttcaaacat attgggtgct     4680

tctgaattcc tgatgattgg atttaagcta ttgaaaattg gataatttaa acttaatgat     4740

ttttataatt ttctgatctt aaaatttggt taatgcctat aatctgttgc tttttctcaa     4800

tatgtgtcct attggaaatt cctcaaatcg ttggtgccat cagtgattta caaacaatat     4860

tttgatattg cagatgactt gcttactgta tttgcattgt tagaaaacag tttgtagaca     4920

atgattcttt tttaataaaa tcaaataatt ctaaaagtgc tagagaattt aactaaaagc     4980

tggttcccaa atgcatagct ggcattttaa tttaaattca aatctacata gagaacatct     5040

gtgtaaatca tctaactgga tttttccatt ggtcattccc aaacacacct atggtcctag     5100

aatccttaag agaagcaccc tgtaaccttt tatgtggttt gcctttaaga ggcccaggtg     5160

cttctccttt atgatttgag ttggcctctt cataaattag tgctgtttac tttcagagga     5220

agcagagaag ttgctgttat gtttttgcat ccgtttaccc tatgcaaagt tgctgtatga     5280

tgccaactaa actactcttt aggcagcctt ctgaggagaa aagcaaccct gtttcaaatc     5340

cactgccaat tcagctcctc tggagtggag ctttctgatt tcttggagca ggaattttag     5400

agattgaaat gaatgatcat ttagtcagat ttatcctgta atttcatgca gctttgtggc     5460

ctttgcagta ctatttataa aatggaccct gatggtgatg aactctttag aacgcattac     5520

tgttaagcct gtgttgagac attgatgctg tctatctcat tttttagaca gtttttgtag     5580

ctttctattg agagtcaggt atgtgagcat ctctgaagca gtgttgaatg taattttcgg     5640

aaacatggat tgtgtatttt gacttttatt ttataaatac acagctcaac agtgcctttt     5700

ttttccctca tagtcctgtt ggaagatgct cactactttc tctcttctct ctccctgccc     5760

tcccccactc cattcagttg attcatttat gcaaattctg tttccaactt gaaaccattt     5820

tgtcacatct gttggagaga taatcactcc ttttccttaa cattctgcca gctttctgat     5880

gttgaagtgt ttcagttgac tacctgatgc aaaagctata aaataaacag tgggaagggg     5940

aaaaattggt gtcctgtttt aatattttct tttgtagcct tgacactgat ggacattttc     6000

caagctgact cagtgttcag tgtcaactta actctcagat agtgttgcca tcaagaaagc     6060

atgcaacatc attggtttct aatgatttta tggcttgtga caatatttta tctggactga     6120

catgcctctg ctgcttttgc tttgtacttc attgctggta ataaaatttc agatggaaaa     6180

cttacaaaat atatacttaa ttagaagaaa aaaatagaga aagggctatt agaattaaaa     6240

aaatttgaaa gtaacttaat ctaacattta tggcacagtt tggacatatc cataattttt     6300

tttgggaaca cacatttctg attttttttt tcccccttaa agaagaaagt ctcaattcca     6360

ttgattttca attcttagcc actggctcat tgctttgagc aatgcttgat tgattctatt     6420

tatattatat gatattgggt tgataaaata ccagttcaat gatgagtttt cttaacagaa     6480

tttggtttgt acttgcagtg gctgaacaaa gagcatggct tgagaatcaa agggatctgc     6540

atttagcaat gtgatgtcag taaatggaca taacaggatt gttgtaaagg ttgggcatga     6600

tgtatgcaaa gtactggcca gggtagacta ataactgatg gcatttatat gctgtgctgg     6660

aatattgtta ccaagctgat gtgccgttct caccctgcag aatactggtt ttgtcatttc     6720

ataaatgata tttttataaa tatttttgaa tgactgtaaa aaaaaaaaaa                6770


<210>  1264
<211>  4326
<212>  DNA
<213>  homo sapiens

<400>  1264
gctgagcgcg gagccgcccg gtgattggtg ggggcggaag ggggccgggc gccagcgctg       60

ccttttctcc tgccgggtag tttcgctttc ctgcgcagag tctgcggagg ggctcggctg      120

caccgggggg atcgcgcctg gcagacccca gaccgagcag aggcgaccca gcgcgctcgg      180

gagaggctgc accgccgcgc ccccgcctag cccttccgga tcctgcgcgc agaaaagttt      240

catttgctgt atgccatcct cgagagctgt ctaggttaac gttcgcactc tgtgtatata      300

acctcgacag tcttggcacc taacgtgctg tgcgtagctg ctcctttggt tgaatcccca      360

ggcccttgtt ggggcacaag gtggcaggat gtctcagtgg tacgaacttc agcagcttga      420

ctcaaaattc ctggagcagg ttcaccagct ttatgatgac agttttccca tggaaatcag      480

acagtacctg gcacagtggt tagaaaagca agactgggag cacgctgcca atgatgtttc      540

atttgccacc atccgttttc atgacctcct gtcacagctg gatgatcaat atagtcgctt      600

ttctttggag aataacttct tgctacagca taacataagg aaaagcaagc gtaatcttca      660

ggataatttt caggaagacc caatccagat gtctatgatc atttacagct gtctgaagga      720

agaaaggaaa attctggaaa acgcccagag atttaatcag gctcagtcgg ggaatattca      780

gagcacagtg atgttagaca aacagaaaga gcttgacagt aaagtcagaa atgtgaagga      840

caaggttatg tgtatagagc atgaaatcaa gagcctggaa gatttacaag atgaatatga      900

cttcaaatgc aaaaccttgc agaacagaga acacgagacc aatggtgtgg caaagagtga      960

tcagaaacaa gaacagctgt tactcaagaa gatgtattta atgcttgaca ataagagaaa     1020

ggaagtagtt cacaaaataa tagagttgct gaatgtcact gaacttaccc agaatgccct     1080

gattaatgat gaactagtgg agtggaagcg gagacagcag agcgcctgta ttggggggcc     1140

gcccaatgct tgcttggatc agctgcagaa ctggttcact atagttgcgg agagtctgca     1200

gcaagttcgg cagcagctta aaaagttgga ggaattggaa cagaaataca cctacgaaca     1260

tgaccctatc acaaaaaaca aacaagtgtt atgggaccgc accttcagtc ttttccagca     1320

gctcattcag agctcgtttg tggtggaaag acagccctgc atgccaacgc accctcagag     1380

gccgctggtc ttgaagacag gggtccagtt cactgtgaag ttgagactgt tggtgaaatt     1440

gcaagagctg aattataatt tgaaagtcaa agtcttattt gataaagatg tgaatgagag     1500

aaatacagta aaaggattta ggaagttcaa cattttgggc acgcacacaa aagtgatgaa     1560

catggaggag tccaccaatg gcagtctggc ggctgaattt cggcacctgc aattgaaaga     1620

acagaaaaat gctggcacca gaacgaatga gggtcctctc atcgttactg aagagcttca     1680

ctcccttagt tttgaaaccc aattgtgcca gcctggtttg gtaattgacc tcgagacgac     1740

ctctctgccc gttgtggtga tctccaacgt cagccagctc ccgagcggtt gggcctccat     1800

cctttggtac aacatgctgg tggcggaacc caggaatctg tccttcttcc tgactccacc     1860

atgtgcacga tgggctcagc tttcagaagt gctgagttgg cagttttctt ctgtcaccaa     1920

aagaggtctc aatgtggacc agctgaacat gttgggagag aagcttcttg gtcctaacgc     1980

cagccccgat ggtctcattc cgtggacgag gttttgtaag gaaaatataa atgataaaaa     2040

ttttcccttc tggctttgga ttgaaagcat cctagaactc attaaaaaac acctgctccc     2100

tctctggaat gatgggtgca tcatgggctt catcagcaag gagcgagagc gtgccctgtt     2160

gaaggaccag cagccgggga ccttcctgct gcggttcagt gagagctccc gggaaggggc     2220

catcacattc acatgggtgg agcggtccca gaacggaggc gaacctgact tccatgcggt     2280

tgaaccctac acgaagaaag aactttctgc tgttactttc cctgacatca ttcgcaatta     2340

caaagtcatg gctgctgaga atattcctga gaatcccctg aagtatctgt atccaaatat     2400

tgacaaagac catgcctttg gaaagtatta ctccaggcca aaggaagcac cagagccaat     2460

ggaacttgat ggccctaaag gaactggata tatcaagact gagttgattt ctgtgtctga     2520

agttcaccct tctagacttc agaccacaga caacctgctc cccatgtctc ctgaggagtt     2580

tgacgaggtg tctcggatag tgggctctgt agaattcgac agtatgatga acacagtata     2640

gagcatgaat ttttttcatc ttctctggcg acagttttcc ttctcatctg tgattccctc     2700

ctgctactct gttccttcac atcctgtgtt tctagggaaa tgaaagaaag gccagcaaat     2760

tcgctgcaac ctgttgatag caagtgaatt tttctctaac tcagaaacat cagttactct     2820

gaagggcatc atgcatctta ctgaaggtaa aattgaaagg cattctctga agagtgggtt     2880

tcacaagtga aaaacatcca gatacaccca aagtatcagg acgagaatga gggtcctttg     2940

ggaaaggaga agttaagcaa catctagcaa atgttatgca taaagtcagt gcccaactgt     3000

tataggttgt tggataaatc agtggttatt tagggaactg cttgacgtag gaacggtaaa     3060

tttctgtggg agaattctta catgttttct ttgctttaag tgtaactggc agttttccat     3120

tggtttacct gtgaaatagt tcaaagccaa gtttatatac aattatatca gtcctctttc     3180

aaaggtagcc atcatggatc tggtaggggg aaaatgtgta ttttattaca tctttcacat     3240

tggctattta aagacaaaga caaattctgt ttcttgagaa gagaatatta gctttactgt     3300

ttgttatggc ttaatgacac tagctaatat caatagaagg atgtacattt ccaaattcac     3360

aagttgtgtt tgatatccaa agctgaatac attctgcttt catcttggtc acatacaatt     3420

atttttacag ttctcccaag ggagttaggc tattcacaac cactcattca aaagttgaaa     3480

ttaaccatag atgtagataa actcagaaat ttaattcatg tttcttaaat gggctacttt     3540

gtcctttttg ttattagggt ggtatttagt ctattagcca caaaattggg aaaggagtag     3600

aaaaagcagt aactgacaac ttgaataata caccagagat aatatgagaa tcagatcatt     3660

tcaaaactca tttcctatgt aactgcattg agaactgcat atgtttcgct gatatatgtg     3720

tttttcacat ttgcgaatgg ttccattctc tctcctgtac tttttccaga cacttttttg     3780

agtggatgat gtttcgtgaa gtatactgta tttttacctt tttccttcct tatcactgac     3840

acaaaaagta gattaagaga tgggtttgac aaggttcttc ccttttacat actgctgtct     3900

atgtggctgt atcttgtttt tccactactg ctaccacaac tatattatca tgcaaatgct     3960

gtattcttct ttggtggaga taaagatttc ttgagttttg ttttaaaatt aaagctaaag     4020

tatctgtatt gcattaaata taatatgcac acagtgcttt ccgtggcact gcatacaatc     4080

tgaggcctcc tctctcagtt tttatataga tggcgagaac ctaagtttca gttgatttta     4140

caattgaaat gactaaaaaa caaagaagac aacattaaaa caatattgtt tctaattgct     4200

gaggtttagc tgtcagttct ttttgccctt tgggaattcg gcatggtttc attttactgc     4260

actagccaag agactttact tttaagaagt attaaaattc taaaattcaa aaaaaaaaaa     4320

aaaaaa                                                                4326


<210>  1265
<211>  1105
<212>  DNA
<213>  homo sapiens

<400>  1265
attgcaactt ggtctcacag tggcttaggc cagggtggga gcagtgaacg gagtcacaaa       60

agaaattttt cagctgtcct ctctgacacc accccggcct gcctctttgt tgccatgaga      120

gctgcctacc tcttcctgct attcctgcct gcaggcttgc tggctcaggg ccagtatgac      180

ctggacccgc tgccgccgtt ccctgaccac gtccagtaca cccactatag cgaccagatc      240

gacaacccag actactatga ttatcaagag gtgactcctc ggccctccga ggaacagttc      300

cagttccagt cccagcagca agtccaacag gaagtcatcc cagccccaac cccagaacca      360

ggaaatgcag agctggagcc cacagagcct gggcctcttg actgccgtga ggaacagtac      420

ccgtgcaccc gcctctactc catacacagg ccttgcaaac agtgtctcaa cgaggtctgc      480

ttctacagcc tccgccgtgt gtacgtcatt aacaaggaga tctgtgttcg tacagtgtgt      540

gcccatgagg agctcctccg agctgacctc tgtcgggaca agttctccaa atgtggcgtg      600

atggccagca gcggcctgtg ccaatccgtg gcggcctcct gtgccaggag ctgtgggagc      660

tgctagggtg gtgctggcat cctgagtcct ggccctcctg ggatctgggg ccctcgggcc      720

ctgcctgacc tggtgctttt ttccccatcc ccatgttcct tttattctgt aaaaagttag      780

tggactgcag ccctgggggt tgcaggctgc ggtgcctcag gcccctcctt cagcctgtgg      840

ccacctctgg ggcacaatgg gggctcccca ctgcccagtc tgcccctcgg gttgggggag      900

tatcccaggc ctctctgtgg gacctgggcc cctgacgggc cttctcagcc cgttttgagg      960

acagacagtc ccccgaggta ggctacatcc ccccacccca gctggtctgc ttggatttcc     1020

tacagccccc gtgggcatgg accaccttta ttttatacaa aattaaaaac aagtttttac     1080

aaaaaaaaaa aaaaaaaaaa aaaaa                                           1105


<210>  1266
<211>  5411
<212>  DNA
<213>  homo sapiens

<400>  1266
gtgtcccata gtgtttccaa acttggaaag ggcgggggag ggcgggagga tgcggagggc       60

ggaggtatgc agacaacgag tcagagtttc cccttgaaag cctcaaaagt gtccacgtcc      120

tcaaaaagaa tggaaccaat ttaagaagcc agccccgtgg ccacgtccct tcccccattc      180

gctccctcct ctgcgccccc gcaggctcct cccagctgtg gctgcccggg cccccagccc      240

cagccctccc attggtggag gcccttttgg aggcacccta gggccaggga aacttttgcc      300

gtataaatag ggcagatccg ggctttatta ttttagcacc acggcagcag gaggtttcgg      360

ctaagttgga ggtactggcc acgactgcat gcccgcgccc gccaggtgat acctccgccg      420

gtgacccagg ggctctgcga cacaaggagt ctgcatgtct aagtgctaga catgctcagc      480

tttgtggata cgcggacttt gttgctgctt gcagtaacct tatgcctagc aacatgccaa      540

tctttacaag aggaaactgt aagaaagggc ccagccggag atagaggacc acgtggagaa      600

aggggtccac caggcccccc aggcagagat ggtgaagatg gtcccacagg ccctcctggt      660

ccacctggtc ctcctggccc ccctggtctc ggtgggaact ttgctgctca gtatgatgga      720

aaaggagttg gacttggccc tggaccaatg ggcttaatgg gacctagagg cccacctggt      780

gcagctggag ccccaggccc tcaaggtttc caaggacctg ctggtgagcc tggtgaacct      840

ggtcaaactg gtcctgcagg tgctcgtggt ccagctggcc ctcctggcaa ggctggtgaa      900

gatggtcacc ctggaaaacc cggacgacct ggtgagagag gagttgttgg accacagggt      960

gctcgtggtt tccctggaac tcctggactt cctggcttca aaggcattag gggacacaat     1020

ggtctggatg gattgaaggg acagcccggt gctcctggtg tgaagggtga acctggtgcc     1080

cctggtgaaa atggaactcc aggtcaaaca ggagcccgtg ggcttcctgg tgagagagga     1140

cgtgttggtg cccctggccc agctggtgcc cgtggcagtg atggaagtgt gggtcccgtg     1200

ggtcctgctg gtcccattgg gtctgctggc cctccaggct tcccaggtgc ccctggcccc     1260

aagggtgaaa ttggagctgt tggtaacgct ggtcctgctg gtcccgccgg tccccgtggt     1320

gaagtgggtc ttccaggcct ctccggcccc gttggacctc ctggtaatcc tggagcaaac     1380

ggccttactg gtgccaaggg tgctgctggc cttcccggcg ttgctggggc tcccggcctc     1440

cctggacccc gcggtattcc tggccctgtt ggtgctgccg gtgctactgg tgccagagga     1500

cttgttggtg agcctggtcc agctggctcc aaaggagaga gcggtaacaa gggtgagccc     1560

ggctctgctg ggccccaagg tcctcctggt cccagtggtg aagaaggaaa gagaggccct     1620

aatggggaag ctggatctgc cggccctcca ggacctcctg ggctgagagg tagtcctggt     1680

tctcgtggtc ttcctggagc tgatggcaga gctggcgtca tgggccctcc tggtagtcgt     1740

ggtgcaagtg gccctgctgg agtccgagga cctaatggag atgctggtcg ccctggggag     1800

cctggtctca tgggacccag aggtcttcct ggttcccctg gaaatatcgg ccccgctgga     1860

aaagaaggtc ctgtcggcct ccctggcatc gacggcaggc ctggcccaat tggcccagct     1920

ggagcaagag gagagcctgg caacattgga ttccctggac ccaaaggccc cactggtgat     1980

cctggcaaaa acggtgataa aggtcatgct ggtcttgctg gtgctcgggg tgctccaggt     2040

cctgatggaa acaatggtgc tcagggacct cctggaccac agggtgttca aggtggaaaa     2100

ggtgaacagg gtccccctgg tcctccaggc ttccagggtc tgcctggccc ctcaggtccc     2160

gctggtgaag ttggcaaacc aggagaaagg ggtctccatg gtgagtttgg tctccctggt     2220

cctgctggtc caagagggga acgcggtccc ccaggtgaga gtggtgctgc cggtcctact     2280

ggtcctattg gaagccgagg tccttctgga cccccagggc ctgatggaaa caagggtgaa     2340

cctggtgtgg ttggtgctgt gggcactgct ggtccatctg gtcctagtgg actcccagga     2400

gagaggggtg ctgctggcat acctggaggc aagggagaaa agggtgaacc tggtctcaga     2460

ggtgaaattg gtaaccctgg cagagatggt gctcgtggtg ctcctggtgc tgtaggtgcc     2520

cctggtcctg ctggagccac aggtgaccgg ggcgaagctg gggctgctgg tcctgctggt     2580

cctgctggtc ctcggggaag ccctggtgaa cgtggtgagg tcggtcctgc tggccccaat     2640

ggatttgctg gtcctgctgg tgctgctggt caacctggtg ctaaaggaga aagaggagcc     2700

aaagggccta agggtgaaaa cggtgttgtt ggtcccacag gccccgttgg agctgctggc     2760

ccagctggtc caaatggtcc ccccggtcct gctggaagtc gtggtgatgg aggcccccct     2820

ggtatgactg gtttccctgg tgctgctgga cggactggtc ccccaggacc ctctggtatt     2880

tctggccctc ctggtccccc tggtcctgct gggaaagaag ggcttcgtgg tcctcgtggt     2940

gaccaaggtc cagttggccg aactggagaa gtaggtgcag ttggtccccc tggcttcgct     3000

ggtgagaagg gtccctctgg agaggctggt actgctggac ctcctggcac tccaggtcct     3060

cagggtcttc ttggtgctcc tggtattctg ggtctccctg gctcgagagg tgaacgtggt     3120

ctaccaggtg ttgctggtgc tgtgggtgaa cctggtcctc ttggcattgc cggccctcct     3180

ggggcccgtg gtcctcctgg tgctgtgggt agtcctggag tcaacggtgc tcctggtgaa     3240

gctggtcgtg atggcaaccc tgggaacgat ggtcccccag gtcgcgatgg tcaacccgga     3300

cacaagggag agcgcggtta ccctggcaat attggtcccg ttggtgctgc aggtgcacct     3360

ggtcctcatg gccccgtggg tcctgctggc aaacatggaa accgtggtga aactggtcct     3420

tctggtcctg ttggtcctgc tggtgctgtt ggcccaagag gtcctagtgg cccacaaggc     3480

attcgtggcg ataagggaga gcccggtgaa aaggggccca gaggtcttcc tggcttaaag     3540

ggacacaatg gattgcaagg tctgcctggt atcgctggtc accatggtga tcaaggtgct     3600

cctggctccg tgggtcctgc tggtcctagg ggccctgctg gtccttctgg ccctgctgga     3660

aaagatggtc gcactggaca tcctggtaca gttggacctg ctggcattcg aggccctcag     3720

ggtcaccaag gccctgctgg cccccctggt ccccctggcc ctcctggacc tccaggtgta     3780

agcggtggtg gttatgactt tggttacgat ggagacttct acagggctga ccagcctcgc     3840

tcagcacctt ctctcagacc caaggactat gaagttgatg ctactctgaa gtctctcaac     3900

aaccagattg agacccttct tactcctgaa ggctctagaa agaacccagc tcgcacatgc     3960

cgtgacttga gactcagcca cccagagtgg agcagtggtt actactggat tgaccctaac     4020

caaggatgca ctatggatgc tatcaaagta tactgtgatt tctctactgg cgaaacctgt     4080

atccgggccc aacctgaaaa catcccagcc aagaactggt ataggagctc caaggacaag     4140

aaacacgtct ggctaggaga aactatcaat gctggcagcc agtttgaata taatgtagaa     4200

ggagtgactt ccaaggaaat ggctacccaa cttgccttca tgcgcctgct ggccaactat     4260

gcctctcaga acatcaccta ccactgcaag aacagcattg catacatgga tgaggagact     4320

ggcaacctga aaaaggctgt cattctacag ggctctaatg atgttgaact tgttgctgag     4380

ggcaacagca ggttcactta cactgttctt gtagatggct gctctaaaaa gacaaatgaa     4440

tggggaaaga caatcattga atacaaaaca aataagccat cacgcctgcc cttccttgat     4500

attgcacctt tggacatcgg tggtgctgac caggaattct ttgtggacat tggcccagtc     4560

tgtttcaaat aaatgaactc aatctaaatt aaaaaagaaa gaaatttgaa aaaactttct     4620

ctttgccatt tcttcttctt cttttttaac tgaaagctga atccttccat ttcttctgca     4680

catctacttg cttaaattgt gggcaaaaga gaaaaagaag gattgatcag agcattgtgc     4740

aatacagttt cattaactcc ttcccccgct cccccaaaaa tttgaatttt tttttcaaca     4800

ctcttacacc tgttatggaa aatgtcaacc tttgtaagaa aaccaaaata aaaattgaaa     4860

aataaaaacc ataaacattt gcaccacttg tggcttttga atatcttcca cagagggaag     4920

tttaaaaccc aaacttccaa aggtttaaac tacctcaaaa cactttccca tgagtgtgat     4980

ccacattgtt aggtgctgac ctagacagag atgaactgag gtccttgttt tgttttgttc     5040

ataatacaaa ggtgctaatt aatagtattt cagatacttg aagaatgttg atggtgctag     5100

aagaatttga gaagaaatac tcctgtattg agttgtatcg tgtggtgtat tttttaaaaa     5160

atttgattta gcattcatat tttccatctt attcccaatt aaaagtatgc agattatttg     5220

cccaaatctt cttcagattc agcatttgtt ctttgccagt ctcattttca tcttcttcca     5280

tggttccaca gaagctttgt ttcttgggca agcagaaaaa ttaaattgta cctattttgt     5340

atatgtgaga tgtttaaata aattgtgaaa aaaatgaaat aaagcatgtt tggttttcca     5400

aaagaacata t                                                          5411


<210>  1267
<211>  6365
<212>  DNA
<213>  homo sapiens

<400>  1267
cctgggcagt ggcggggctg gccgaggctg cggcgtttct ccccaaggaa gtgtcttctc       60

cgctttccct gttcttctgt ttctcacaca ctttctatct cattctgtaa ctttcaagcc      120

tttccttcta actgtatgta tttagttact tgttttcaag ctggttccct ctctggcccc      180

ctggcctggg gaaagcctcc acacttactg cgggtcttgt ttagagtctg agtttgtgag      240

attatttggg ggagagtggg cgagtggctg acaggtgacc cccaggagga ggattcctgg      300

ggctggtgtc ttctcccagc tgctgcttcc agtgggcctg ggcccaggac tggacctccg      360

ctggcacccc tgagtgcctc cctgccaggc catgctgctg tagaccctaa cagcgtctct      420

tcctggccaa gagaagcctg tccccaagaa caggagagcc atggccggcc tccgagggaa      480

cgctgtggct ggcctcctct ggatgctgct gctgtggagt gggggcggcg gctgccaggc      540

tcagcgggca ggttgcaaaa gtgtccacta cgatctggtc ttcctcctgg acacctcctc      600

cagcgtgggc aaggaggact ttgagaaggt ccggcagtgg gtggccaacc tggtggacac      660

cttcgaggtg ggccccgacc gcacccgtgt gggggtcgtg cgctacagcg accggcccac      720

cacggccttc gagttgggac tctttggctc gcaggaggag gtcaaggcgg ctgcccggcg      780

tctcgcctac cacgggggca acaccaacac gggagacgcg ctccgctaca tcacggcccg      840

cagcttctcc ccacacgccg gcggccgccc cagggaccgc gcctacaagc aggtggccat      900

cctgctcacc gacggccgca gccaggacct ggtgctggac gccgcggcgg cagcccaccg      960

cgctggcatc cgcatctttg ccgtgggcgt gggcgaggca ctcaaggagg agctggagga     1020

gatcgcctca gagcccaagt ccgcccacgt cttccacgtg tccgacttca atgccatcga     1080

caagatccgg ggcaagctgc ggcgccgtct ttgtgaaaat gtgctctgtc ctagcgttcg     1140

tgtagaagga gatcgcttta agcacaccaa tggaggaacc aaggaaatca caggttttga     1200

cctgatggat ttgttcagtg tgaaggaaat cttggggaag agagagaatg gagctcagag     1260

ttcctatgta cggatgggat ccttccctgt ggtgcaaagt actgaggatg tgttccccca     1320

aggtttacct gatgagtacg cctttgtcac aaccttccgg ttcaggaaaa cctctcggaa     1380

ggaagactgg tatatctggc aggtcatcga ccagtacagc atcccacagg tctccatccg     1440

gctggatggt gaaaacaagg cagtcgagta caacgctgtg ggtgccatga aagatgctgt     1500

cagggtggtc ttccgaggtt ctcgggtcaa tgacctcttt gaccgggact ggcacaagat     1560

ggccctgagc atccaggccc agaacgtctc cctgcacatt gactgtgcgc tggtgcagac     1620

actacccatc gaggaacggg agaacattga catccagggc aagactgtga ttggcaagcg     1680

cctctacgac agtgtgccca ttgactttga cctacagcgg attgtgatct attgtgactc     1740

gagacacgca gaattggaga cttgttgtga tatcccctcg ggtccgtgcc aggtgaccgt     1800

ggtgacagag cctccacctc cacccccacc ccagcggcct cccaccccag gcagtgaaca     1860

gattgggttt ttgaagacca tcaactgctc ctgcccagct ggagagaagg gtgaaatggg     1920

agttgctggc cccatggggc tccctggtcc aaagggagac ataggagcca ttgggccggt     1980

tggcgctcct ggacctaagg gagagaaagg tgatgtgggc ataggacctt ttggccaagg     2040

ggaaaagggt gaaaagggtt ccctgggcct gcccggcccc cctgggagag acggcagcaa     2100

aggcatgaga ggggagccag gagagctggg agagccgggg ctgccgggtg aggtcggcat     2160

gcgggggccc caaggaccac ctggactccc cggacctcct ggacgtgtcg gagctcctgg     2220

tctccaagga gaacgaggtg aaaagggaac tcgaggagaa aagggagagc gaggcctgga     2280

tggattccct gggaagcctg gggacacagg acagcagggc aggcccggcc cttctggtgt     2340

ggcaggaccc cagggagaaa agggtgacgt gggacctgcg gggccacctg gtgtaccagg     2400

ctcagtggtg cagcaagagg gcttgaaagg ggaacaggga gctccaggac ccagaggtca     2460

ccaaggcgcc cccggtcctc caggagctcg gggtccaata ggcccagaag gcagggatgg     2520

acctcctggt ttgcaaggtc tccgagggaa gaaaggtgac atgggaccac ctggaatccc     2580

tggattgctg gggctgcagg gccctccagg accccctggt gtcccaggcc cccctggacc     2640

gggaggttct ccgggtttgc ctggagagat cggcttcccg ggaaagcctg gacctcctgg     2700

gcccacggga ccccctggaa aggacgggcc aaatggacca ccaggtccgc caggaaccaa     2760

gggagaacca ggagaaagag gggaagatgg tctgcctgga aaaccaggcc ttcggggaga     2820

aattggggag cagggcctgg caggccgacc tggagagaag ggagaagcag gcctcccagg     2880

ggctccaggc ttcccaggtg tgagaggaga gaaaggagac cagggagaaa aaggtgaact     2940

gggacttcca ggactgaaag gtgaccgagg tgaaaagggt gaagctggtc ctgcaggccc     3000

tcccgggtta cctggaacta catccctgtt cacaccacat ccacggatgc ccggagaaca     3060

agggcccaaa ggagagaagg gcgatccagg cctgcctggg gaaccgggac tgcagggccg     3120

tcctggagaa ttggggcctc agggacccac tggaccaccg ggtgccaagg gacaggaagg     3180

tgcacatggg gctcctggag cagctggaaa ccccggtgct cccggacatg tcggtgcccc     3240

cggtcccagt ggccctccag gaagtgtggg tgctcccggc ctcagaggca ccccagggaa     3300

agatggggag cgtggtgaga agggtgcagc gggggaagaa ggcagcccag ggccagttgg     3360

tcccagggga gatcctggtg ctcctgggct ccctgggcca cccggaaaag ggaaggatgg     3420

agagccggga ctccgtggat cacctggact ccctggaccc ctaggaacca aggctgcttg     3480

cggaaaagtc agagggtcag aaaactgtgc actgggaggg caatgtgtta agggggatcg     3540

aggagctcct gggatccctg gttctcctgg cagccgtggt gacccaggca ttggggttgc     3600

tggccctcct ggcccttccg gaccaccagg agacaaagga tccccgggat cacgaggctt     3660

acctggattc cctggccccc agggcccagc cggccgggac ggtgcaccag gaaatccagg     3720

agaaagaggg cctcctggca agccgggcct ctcttcacta ctgtctccag gggacataaa     3780

tctcttggct aaggatgtgt gcaatgactg ccctcctggc cccccaggcc tccctggtct     3840

accaggtttt aaaggggaca aaggtgtccc aggaaagcca gggagagaag gcacagaagg     3900

gaaaaaggga gaggctgggc ctccaggcct accagggccc ccaggaatag ctggaccaca     3960

gggaagtcaa ggagaacgtg gtgcagatgg tgaggttggg cagaaaggtg atcagggtca     4020

tcctggagtt ccaggtttca tggggccccc agggaaccct gggccaccag gggcagatgg     4080

aattgcagga gctgctggac caccaggaat ccaagggtca cctgggaaag aaggccctcc     4140

tggcccccaa ggcccatctg gattacccgg aatcccagga gaagaaggca aagagggcag     4200

agatggaaag ccgggtcccc ctggagagcc gggcaaagca ggagagccag gtctaccagg     4260

accagagggt gcccgaggcc cacctggctt caagggacac acaggcgatt ctggtgcacc     4320

cggtccccgg ggagagtctg gtgccatggg gcttcctggt caggaagggt taccaggaaa     4380

agatggtgac actggaccca ctgggccaca gggtccccaa ggaccaaggg gcccaccggg     4440

caagaatgga tcaccgggat ctccaggaga gcctggccct tcaggaaccc ctggccagaa     4500

aggaagcaaa ggggaaaatg gcagcccagg acttcctggc ttcctgggtc cccgtgggcc     4560

tccgggagaa ccaggagaga aaggagtccc aggcaaggag ggggtccctg ggaagcctgg     4620

agagcctgga ttcaaaggag aaaggggaga tcctgggatc aaaggtgaca aaggacctcc     4680

tggtggaaaa ggccagcctg gggaccctgg aatcccaggc cacaaaggcc acacaggcct     4740

gatgggtccc caaggactac ctggggagaa tggaccagtt ggacccccag ggcctccagg     4800

ccagccggga tttccaggac tgagggggga gtctccatcc atggaaaccc tgcgtcggct     4860

tattcaagaa gagctgggga agcagcttga aaccagactc gcctacctcc tggcccagat     4920

gcccccggcg tacatgaagt catctcaagg cagacctggg cccccagggc cccctggaaa     4980

agatgggctt ccaggccggg ccggccccat gggggagcca ggtcgtcctg ggcagggggg     5040

tctggaagga ccctctggac ccataggtcc caaaggtgag cgaggagcca aaggtgaccc     5100

aggtgcacct ggagttggcc tccgaggcga gatgggaccc cctggaatcc caggtcaacc     5160

cggggaacct ggctatgcta aagatggact tcctgggatc cctggccctc aaggggagac     5220

aggaccagct ggacatcctg gcctcccagg acctcccggt cccccaggcc aatgtgaccc     5280

ttcccagtgt gcctacttcg ccagccttgc tgcccggccg ggtaatgtga agggtcccta     5340

aaggactctg gaaagccaga agactgcagt ggatttctga aacttgaact cagagcccag     5400

tgggaagcca gaggtcttga aagacttcag ccatgtgttc cttttttttt tctttctttt     5460

atcgtttgct ttttgtttta ttttcttgag agacctcaaa attattaaat ccaacagacg     5520

ctgccggtcg gtcagattat tattaatatt attgttgttg ttaattatta ttattatttc     5580

atatgctgat gctttgtgag ttcttttcca ctcctttaaa gttgggaaaa cttgattcgt     5640

ggggcaggag attgtttctt cattcttctg acagccccca tctgacgcgt aactgcccat     5700

tttaaggaaa ctcttggtgc tacaaaaccc tgaccagaca cttggcaaat ttacctcttt     5760

cttcaaaaga aaaactttaa gaaaatgagc caatgggctt cattctcagt catgcccgga     5820

gatcacccag gagaaataat acaaacacca ccactgtcca gagagagtaa agaagcagaa     5880

agagaaagaa tttgcaacca tgaggaatgt tcccacctcc cgacgggacg tgcatttgga     5940

aaacacagaa tcagccctca gggtgcactc cagccacctc agtgctctaa gctcacagaa     6000

gtgaaataat gtctgtgggt tggcaatggc tttgtgggat catatgtctt ggccaaagat     6060

gggaaaacct atgttgaaga ggcagccctt gagtgttaat ttgtcttcta aactgtgtaa     6120

ggccccttca agttcctctt gttggtttca attatattaa ttataaaaca agtggatgtg     6180

gtgaccatcc acttgtgttt ccctaatgat gggcagttgg ccagggcact gaccagagct     6240

gggaaatttg tatctccaag gcggctctgt ctctgaaata aatggcatca agtgcatgtg     6300

tgtatgcgac atgccctgcc tgaacaggtg ctcaataaat ccaagtttcc ttctcttgaa     6360

aaaaa                                                                 6365


<210>  1268
<211>  10998
<212>  DNA
<213>  homo sapiens

<400>  1268
gattcacagg gcctctgagc attatccccc atactcctcc ccatcattct ccacccagct       60

gttggagcca tctgtctgat caccttggac tccatagtac actggggcaa agcacagccc      120

cagtttctgg aggcagatgg gtaaccagga aaaggcatga atgagggggc cccaggagac      180

agtgacttag agactgaggc aagagtgccg tggtcaatca tgggtcattg tcttcgaact      240

ggacaggcca gaatgtctgc cacacccaca cctgcaggtg aaggagccag aagggatgaa      300

ctttttggga ttctccaaat actccatcag tgtatcctgt cttcaggtga tgcttttgtt      360

cttactggcg tctgttgttc ctggaggcag aatggcaagc caccatattc acaaaaggaa      420

gataaggaag tacaaactgg atacatgaat gctcaaattg aaattattcc atgcaagatc      480

tgtggagaca aatcatcagg aatccattat ggtgtcatta catgtgaagg ctgcaagggc      540

tttttcagga gaagtcagca aagcaatgcc acctactcct gtcctcgtca gaagaactgt      600

ttgattgatc gaaccagtag aaaccgctgc caacactgtc gattacagaa atgccttgcc      660

gtagggatgt ctcgagatgc tgtaaaattt ggccgaatgt caaaaaagca gagagacagc      720

ttgtatgcag aagtacagaa acaccggatg cagcagcagc agcgcgacca ccagcagcag      780

cctggagagg ctgagccgct gacgcccacc tacaacatct cggccaacgg gctgacggaa      840

cttcacgacg acctcagtaa ctacattgac gggcacaccc ctgaggggag taaggcagac      900

tccgccgtca gcagcttcta cctggacata cagccttccc cagaccagtc aggtcttgat      960

atcaatggaa tcaaaccaga accaatatgt gactacacac cagcatcagg cttctttccc     1020

tactgttcgt tcaccaacgg cgagacttcc ccaactgtgt ccatggcaga attagaacac     1080

cttgcacaga atatatctaa atcgcatctg gaaacctgcc aatacttgag agaagagctc     1140

cagcagataa cgtggcagac ctttttacag gaagaaattg agaactatca aaacaagcag     1200

cgggaggtga tgtggcaatt gtgtgccatc aaaattacag aagctataca gtatgtggtg     1260

gagtttgcca aacgcattga tggatttatg gaactgtgtc aaaatgatca aattgtgctt     1320

ctaaaagcag gttctctaga ggtggtgttt atcagaatgt gccgtgcctt tgactctcag     1380

aacaacaccg tgtactttga tgggaagtat gccagccccg acgtcttcaa atccttaggt     1440

tgtgaagact ttattagctt tgtgtttgaa tttggaaaga gtttatgttc tatgcacctg     1500

actgaagatg aaattgcatt attttctgca tttgtactga tgtcagcaga tcgctcatgg     1560

ctgcaagaaa aggtaaaaat tgaaaaactg caacagaaaa ttcagctagc tcttcaacac     1620

gtcctacaga agaatcaccg agaagatgga atactaacaa agttaatatg caaggtgtct     1680

acattaagag ccttatgtgg acgacataca gaaaagctaa tggcatttaa agcaatatac     1740

ccagacattg tgcgacttca ttttcctcca ttatacaagg agttgttcac ttcagaattt     1800

gagccagcaa tgcaaattga tgggtaaatg ttatcaccta agcacttcta gaatgtctga     1860

agtacaaaca tgaaaaacaa acaaaaaaat taaccgagac actttatatg gccctgcaca     1920

gacctggagc gccacacact gcacatcttt tggtgatcgg ggtcaggcaa aggaggggaa     1980

acaatgaaaa caaataaaag ttgaacttgt ttttctcatg catatgattt ccattatgcc     2040

tacagatatg gacccttttt ctgtcttgac ttcttgatca ttgacctctg tttacaacag     2100

gaggagggta ctaaagtcgg aggatttcct tttcttgtag ctcactgccc acagactttc     2160

tacagagtca ccaatctgtc agtaacaaca gagagtccag caataatcgg tgactggtgt     2220

gcatagcgga ggttgcggca ttactttgca caactagctc tttgtttcat gaaggaagtt     2280

tttatttttt caccgattat tgccagtccg caggatggca tgaaaagggt ccatagcagt     2340

agcaacaata gcattataat atattacagg gtaaatgggc atgaagacta tatatagcta     2400

aaagagatat tgtttatata ttgttttaag taatataaaa tgtagttact ggtgtagctt     2460

ttcctgttga attgataagg cactttcatt ttgcaccttt ttctttaaat taaatgctag     2520

cgtgttcact gtcgtgtcgc atgtgcacca gaaacacaag tttaactgag aaggcttgga     2580

aggtacgttg ggaggtattt atgctgctgt ttacaaaatt atttttaaga gactggctgg     2640

tcatatctag aaatcaccac gttggatttt ttttttaaca tgtgaatttg gaattagaaa     2700

cggaactctc cctaaattat actttgcttt ttggtaagtt taatgataga tgtgtttatg     2760

cttcatacaa agttgaatga ttgattggcg tggtggacat ataccatcat gctcattttt     2820

tttttttaaa gctttttaaa atgccacctc atggaggcga gggggaggag aagctcattt     2880

tacacaattc agtagttaaa tatggactcg gtctcaactt ggaattctta tgctttgaga     2940

acaaatcaac aaccagaata tttattggaa tctagctttt attataagaa ggacccaaag     3000

attatatcct gagcaaatgc acactcccca tgtgaggaca tgaagtattt actttgtgaa     3060

tgtttatgtt cttggtataa tctaggaacc ctatgagttt atctcagagt gaactaattc     3120

tagatttgtt gtcaatagat gctataattc aagaatgttg ctctccatat ttgaaaaacg     3180

atggatagga gggtgaggga agcatacaat gttgaaccag tttctcttat ttaaatatta     3240

aatactttaa gcctttaaag tgaagttgat gctagctgca aacatttact cttgtattta     3300

tcttcactag gaaactgtgg actgtaattt attttattaa atatttagaa gattatttgg     3360

cttgtgtgtt caggtgagaa atactgagtt gtttttgttt aatttcatgg tttttttttt     3420

tttaatgatc cctagtgggg gaaggggaaa ggaatagtct gataaacaga tgtgcatatt     3480

ttaaaaacaa gtgacctttt gggaatgtag gcatttagac gatgatttta gtcgcactag     3540

gggtgggatt caaactactg gtcaaagacc attttgtaca gaaaagggaa catctccgat     3600

gggtgttaag gtaggagttt ccatgcagcc ctttatgtct gagaaatagt ctcctctgcc     3660

attggggtcc ctgcggaatc ttctacagga attgcagctc ttcacgtcat gctaggttac     3720

cagcatgggc ttcccagagc acttcactct gtttctaact ccactgactt ttctgacttg     3780

tttcttgagg gacttggaaa aggggaaggt attattcaca cagatgtgtg tatgaagcct     3840

aaataacatc caactttttt tccaaaaaca tagtaagagt ttaaccataa atagaagagt     3900

aatattcctt taaatttctt acaggcatgt aaaattttat gtgtttatag agagatgcta     3960

actgtcagca tatagtattt atattggggc aagaagggtt aaatcaaatc tttaatttaa     4020

gtaagcatag ttcctttaaa gatcagtagt atttatactc tgaaaagagt accaagctta     4080

gttcagttat ttattcatcc attttttttc tattgtttct cctctggggg gaaatggtgt     4140

tttgtttttg tttgagtttt gtgttttagt tttttggttt tggttttgtt ttgttttttt     4200

gtcattcaga ttcactaaat ttggggatgg ttttattaaa gtatattaac ttctttttaa     4260

ccaaagcttt ctgaatatga ccagcctcag gtgctagcgc attaaagagc aactaaacct     4320

aattccagtg tcgatttgtg aaataataaa agctaattga atttctctaa gggtgagaga     4380

gaacataatg atgaacttaa aaagaaattc cttttcccag aagggattct gcatgtacct     4440

acaaacaatc atgctctaac cacagtaata gtcatgccat ggtgacattg cttttacggt     4500

aaaccaagat aggtaatatg atgcttcttc ccaggtgttt ctgaaagaaa agcagcggtg     4560

gagcttaaga gccaagtcca ctgattgaca taataggatg gaattgtaga cagagacatg     4620

ctccatgaaa caaggaaaca actgactact atttggatct aagttgggat ctgatgttaa     4680

acaataaatt cagtttaaaa aaaatatgga gctcagaaaa ggatgtgaaa aactttgcat     4740

tttcctttct tcattattac aaaaacacct atgtgatgac ataaaatact tgggtgatat     4800

cagaacaatt atccttaata gtttttataa ttaaagtttc ctaaacttca gtctccaata     4860

gtcttttaag gattggaacc acatcactgt cagccccgct gctacaatgc ctttgtacaa     4920

tttttttaca taaggcaaat aaggcttttg tacaaagcct gaataccttc tgttccaatg     4980

gtgtccaaat ggttattata ttgtgaaaaa cctggccttg gtcacaatgc aaacaaaagt     5040

acagatgaaa gtgctttttg gacagtttgc aaattgtgtt aaagctacgg atttttttta     5100

aagtgttcag catcttaacg tgtattaaag ctatggattt ttttttaaag tcttcagcat     5160

cctaattcac cctttctaac ttaagaaaaa catgacttaa gacactgctt ctaagtttgg     5220

ttgttcttta tagtgtggat acccagttat ctgtgagcgt atgggggtgg gctgagggtc     5280

aggtgaggaa ggagtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgatttgcat     5340

gtgtatgatg tgtgtgcgtc ggaccgcttc taggctacta agtgtcaatg gaaaagaaaa     5400

tgtattcaaa atacttaaat caaaactaga agatggggaa aaaaagattt attctataca     5460

aagccttgtc tggaccactt tagagagact tctatttttt taacccttct ataaatattt     5520

gatggcactt gaaatattcc tgcaataaaa tgtgatttgt gtaaagaaaa aaagattttg     5580

taatgtgaaa caaagaaaga aagtaatgta attttctaaa aaaaaaaata caaacaaaca     5640

aactttgtat tattttcttg atggaatttg tctatctgtc tttggaaaac tttttatttc     5700

attgaatgtg ccatagtaga aatgtgtgtt tttagtttta gactaaggaa tagctagttg     5760

ttgtgttccg acattccaaa atgcaaaaca acctagtagt atctttcatg aaaaggttta     5820

agtagtatgt aagcttctct cattgttgct tttttgcaca tgttcttcat tcctctctag     5880

tgcaatatgt acatagagca cttgcgggtg taccttgatc cctcagggaa aaatacatat     5940

ttgtacagtt ttttggggtt tttttgtttt ttggtttttt ttgttttgcc ttttgttttt     6000

ggctaaggaa tgtcgatcga atcacttgtt attgttgagg ggcagccaga taataatcct     6060

aaagccactg tttccaacat tgattgttta aatcatatgt ccttccaatg ctattatttt     6120

aagataataa taaaaagtta ttttctgaca gttctttgtg ctgactggtg aaaaacaagg     6180

gtaaataagc accttataat tgacttactg tgaatgacaa tccatcttgg tatcaacgat     6240

agaagcccta tcattttgga gttggggtta agagtcagaa acaatgtgct cagggatctc     6300

ctaaaactct taaaacaggg tggccagtac tactgggaca aattgtgttt tttattatta     6360

ataataatga taataatact atccctccaa ggcacaagtg aactatatag aactgcgtgt     6420

gtgtaaactc tttactctcg tctcattttg ttgagtttag aacttgatgt gctcgtcagt     6480

cttgtgtttc aaaacactga ataacttcca aagcaaagtt atgccagtgt gttcaaaaga     6540

taaattaata atgtaccagc aaagagcatc attcaaagta tagtccttgc atattccagt     6600

taccatttct ctaataatta aaatattcat gataaatata tatatagcat catatgttaa     6660

aaactatttc aaattctaca tattaaggat gaaaatttta aaatccagta ataagaggag     6720

agacctgcct atcagtacag tgatataggt aaaagatgaa atatgttttt aaaataccag     6780

caattaacta ttgttttcat gggttctcct ctagaagcaa accaaaaatt ccttcatgga     6840

aaacaattct tacttctaca tgtgtagttt atatctgatg cattacaaga gctaatgttt     6900

aaagacaaaa caaaacctgc ctgtatgaca gcagcaactc gagccaacat ttagtgttac     6960

atgttatatt tttgaaatac cgttttgtta tcatattcca catattactt tccataaagt     7020

cagagaagtt caatgtaatt gttggctctg attcttccac cttgggatac acattcacaa     7080

gaagatttat atattttctt actatgatag aggaacataa tctgggaaaa cttcccatgt     7140

ctgtaagatg aaaaggatac ctttaccatg ttgtttttga taataaagaa tatggaaaat     7200

ggtagaaatc tctcctctct atgtgtattt gtatatgtgt gtatacacac acacgttgac     7260

atttttacat aacatgtgat tgccacttct tataaagtta tgatatagaa ccccatgaaa     7320

acaactttat attatagatc aaataatgtg cccagaaacg caattgcaac agtaaatctt     7380

gatctattgg taagagtcta tgatacaggt cttcattcta tccctaaaca taatgttagt     7440

aaagaggttc catcagattg tattatagag accttcctat tgctatttat ttttaagaga     7500

tgagaagact gactagcaat gtctccacag tgcaattggt ttcacttctg ggtctgtctg     7560

tctgtttgtg taggtgagat cagtgttgtc aggctctcag aataattttt aaaagaatcc     7620

agaagcctga cttcacacca agtagccatc ctagatgggc gggggggatc tccatgttca     7680

accaaaccct cagaacttag agcaataaat acattcagtc atttatttat aaatgaatga     7740

cagaatattc aatccaaata gaaacaacct tttgtcagtg atgcaacata acatggagtc     7800

ttatattgag aaagtgaata tgaatatttt aaatagatgc ctaggaaatc tgtgtttgct     7860

gtttacattt aatgtacttt gccacattag cagtaccaca cttcttttac tttcatcctt     7920

ctaagaacta atgaaagata gcttgctatt agctttgaca tgttgcacat gccattatgt     7980

tgttctctaa gaacaactaa attctctcca gtgttcatgt gtgattcctt tttcatcatt     8040

attactttaa tgtggatgaa tactatttct aggaacttga ttatcactga acagattgca     8100

tatgtaaatg cagataattc ttgagcaata tagtgaaaat gatttcacaa aaaaaatcca     8160

tatgtactgt atacatcttc ctgaatccaa aattctcctg ttatccacac agtttgaaat     8220

ctcatattaa acagtggtaa atttttaaac attaggacat tagctggctg cttctataaa     8280

tgtacctgta ttgtctgcct gctccttttg tggagatgtg tttttgtatt ggatgtttgg     8340

gccaatggga ggcttcaagc tacaacatat tttcccactt taaataatat ttaacatatg     8400

acaaacccca gacaaggctt ttaatatgta taaagaactg cagtgttagg tggtttattt     8460

gcaaactgtt ttcagtgttg tccattttta tggcaccttt aacaatattc ttgtttccaa     8520

agtacaaaaa aaataggtta aataatctag ccataactga atgtcaagca ataaaacaaa     8580

tgacttttgt gcatagactt aaaaaataca aattttagac atctgcatgt aaatgcaatc     8640

tcttgtttac tgctttcttc aacttgagca atcgattcct tatttactat taacttaaga     8700

acttgtaacg gcctgtaaac attttctctc ttactcttct ttcaaattta cctgtccctg     8760

cttttgagtc ataatattta atgttgttct gcacatctct atacagttaa ctttttggct     8820

ttcattctgt atagataaga aaatgttata ttataaacag cctactcagt gcaaatattt     8880

atctgtttat caaatccaca atatgctgta taataccggt tttactatat aatctatttt     8940

agacatagct gtttagaact agagtgtgct atttttgtgt ttttctgatg tgtggtgcta     9000

gacaagttac ttttgtgaac aacaaaaatt atccctttta ttcctagaca ataccacctt     9060

tgggtcttgt taatttcact gagtataact atatatttgt atatatatac atatatatat     9120

atatctacct atgcccaact ggcagctgta tcagagtgct ggatttggga catgcttttc     9180

tctttaaata cataatatca ttatataaat tattctagag tgtatttaat taggataaaa     9240

ttacttcctt agtatggata tttgacatct atagggtgaa tttgtttata aatatggcta     9300

tatggaaact tattagcatt tactttatgt ttgctacttg gctttacagc atatctccta     9360

agctgaaaaa taatttgcca ggccttcaag atcctaaaga aacttgttta atggagtaat     9420

atactttttt ttcttattaa ggaattgtat tactggcacc taacacagtt gtattcttag     9480

ctcctattat agataatggg catttacata aaatatccta gatggcttga tggcagaata     9540

aacctttccc ctcctacctg agtcatgaga aggatggaga cgtcctctgc cataacatgg     9600

gccataaagc aaattcgaca tgggatgttc tgtttcagta tgacctcaac cagttccatg     9660

aactgagtga aggaccttca ttttcaaagt tatttaataa gtagcttaat taagcctttc     9720

tacccattct cccaagatct actggcatta ttgaaaagca aagtttatca aatatctaac     9780

taaggatgta gttaacctta ttaaatattg attagaattg ttctgtaata ttactgaatt     9840

tgtaagatct ttagcaaaga tttttgagca atttataaat gtagagcaaa tgtttctgtt     9900

tactgcactt tttgtaactg aaggtgataa attctcaagc catgattatt ggcttccatg     9960

cactgcaata tttatccaca attctagaca ttttccattt ttgtggaaga gttgctgtta    10020

ccttaattat aaatgcaatt gtgtggttaa tgagagctaa tgctagtagt taacctttta    10080

aagtggattg gctacagttg agggagaaat ctcttttaat ataaatcaca tcattcctta    10140

actgcctctc ttggaaagag attgaaacct tttttttaaa gcacgattta gcatcctaag    10200

cttcctgagg gtagagattg tatctttttg cgtctgcaca atggctagca catgtcagca    10260

tttgacaatt gttaaatgat aacaagtgtg ccccaattaa aacgtttttc ctgggttgtt    10320

ttgttaaatt tacaaagtaa gccaagcctt acggttaaca ttctcctcta caaccaagta    10380

ttaaagccac atttaaaaag accacatgaa atgctgattc taattgtgtg taggtcttga    10440

ggattaagca cacaaatttc acaaacttct gtttgagtaa acaaactcag ccttctgtaa    10500

atatacatgc aagtttggaa acagtaatac tgtacctata aatatatgct gtctgttttg    10560

tgtacagtat gtaaaaactc cttttctgcc acactaaaaa tgcaagccat ttatgggaat    10620

cctaaaacta gtattgaact aaaactttgc taatgatctt tattagagga tcgtccaact    10680

tttcacttac cttgggtttt cttttcaatt cactcttaca ctagtctgct tatttccagc    10740

tgtttatttt attgagtcct gaatttaaaa aaaaaatatt ttgattcatt ttgtaaatac    10800

aagctgtaca aaaaagagag atttaatgtt gtcttttaaa tactccaatt ttcattctaa    10860

tatgaatgtt gttatattgt acttagaaac tgtaccttta atattacatt acctttatta    10920

aaagtgcatt gaacacatca attttagatg tgctttatgt actgttatcc tataataaaa    10980

cttcagcttc taatggaa                                                  10998


<210>  1269
<211>  6114
<212>  DNA
<213>  homo sapiens

<400>  1269
gtcatgcata cattagagcc tctgatgagt ttgtctttgg ggactctggg gctgtactac       60

ccagtgtcat cacaaattac caggagaaat tgcttccagc tcacaatcac atctgctttt      120

ggcaagaact aatgcaccaa gacttcaagt tctaagcctc tgttcagatt ttaattgcaa      180

ttgatcaggt ttatattatt gtacctccag agacctccta gagccagaac ccggctggct      240

tgctgtttcc tttagagcag cgcatatcat tatttggtgt tctggtggag gacttttctg      300

atggcagaaa ttagtttctc tgggttcatc aggacgggat gcttcaagat ttaagtgcaa      360

gtgtcttctt tccaccttgt tcacaacaca gaacgttagc tcaggtacct gacaatgatg      420

agcagtttgt accagactat caggctgaaa gtttggcttt tcatggcctg ccactgaaaa      480

tcaagaaaga accccacagt ccatgttcag aaatcagctc tgcctgcagt caagaacagc      540

cctttaaatt cagctatgga gaaaagtgcc tgtacaatgt cagatttcgc cgccagcttt      600

ctgaaccctg taactccttt cctcctttgc cgacgatgcc aagggaagga cgtcctatgt      660

accaacgcca gatgtctgag ccaaacatcc ccttcccacc acaaggcttt aagcaggagt      720

accacgaccc agtgtatgaa cacaacacca tggttggcag tgcggccagc caaagctttc      780

cccctcctct gatgattaaa caggaaccca gagattttgc atatgactca gaagtgccta      840

gctgccactc catttatatg aggcaagaag gcttcctggc tcatcccagc agaacagaag      900

gctgtatgtt tgaaaagggc cccaggcagt tttatgatga cacctgtgtt gtcccagaaa      960

aattcgatgg agacatcaaa caagagccag gaatgtatcg ggaaggaccc acataccaac     1020

ggcgaggatc acttcagctc tggcagtttt tggtagctct tctggatgac ccttcaaatt     1080

ctcattttat tgcctggact ggtcgaggca tggaatttaa actgattgag cctgaagagg     1140

tggcccgacg ttggggcatt cagaaaaaca ggccagctat gaactatgat aaacttagcc     1200

gttcactccg ctattactat gagaaaggaa ttatgcaaaa ggtggctgga gagagatatg     1260

tctacaagtt tgtgtgtgat ccagaagccc ttttctccat ggcctttcca gataatcagc     1320

gtccactgct gaagacagac atggaacgtc acatcaacga ggaggacaca gtgcctcttt     1380

ctcactttga tgagagcatg gcctacatgc cggaaggggg ctgctgcaac ccccacccct     1440

acaacgaagg ctacgtgtat taacacaagt gacagtcaag cagggcgttt ttgcgctttt     1500

ccttttttct gcaagataca gagaattgct gaatctttgt tttatttctg ttgtttgtat     1560

tttattttta aataataata cacaaaaagg ggcttttcct gttgcattat tctatggtct     1620

gccatggact gtgcacttta tttgagggtg ggtgggagta atctaaacat ttattctgtg     1680

taacaggaag ctaatgggtg aatgggcaga gggatttggg gattactttt tacttaggct     1740

tgggatgggg tcctacaagt tttgagtatg atgaaactat atcatgtctg tttgatttca     1800

taacaacata agataatgtt tattttatcg gggtatctat ggtacagtta atttcacgtt     1860

gtgtaaatat ccacttggag actatttgcc ttgggcattt tcccctgtca tttatgagtc     1920

tctgcaggtg tacaaaaaaa ccccaatcta ctgtaaatgg cagtttaatt gttagaaatg     1980

actgtttttg caccacttgt aaaaaggtat ttagcgattg catttgctgt ttgttgtttt     2040

attttgcttt atatatgact tgcagaggat aaccataaaa tgggtaattc tctctgaagt     2100

tgaataatca ccatgactgt aaatgagggg cacaattttg gactctggcg ccaaactgag     2160

tcataggcca gtagcattac gtgtatctgg tgccaccttg ctgtttagat acaaatcata     2220

ccgtctttta aatattttga agcccatttc agttaaataa tgacatgtca tggtcctttg     2280

gaatcttcat ttaaatgtta aatctggaat caaaatgaag caaaaaatat ctgtctcctt     2340

ttcactttct tcagtacata aatacattat ttaatcaata agaattaact gtactaaatc     2400

atgtattatg ctgttctagt tacagcaaac actctttaag aaaaatatcc aatacactaa     2460

ataggtacta tagtaatttt tagacatggt acccattgat atgcatttaa accttttact     2520

gctgtgttat gttgataaca tatataaata ttagataatg ctaatgcttc tgctgctgtc     2580

ttttctgtaa tattctcttt catgctgaat ttactatgac catttataag cagtgcagtt     2640

aactacagat agcatttcag gacaaaatag atgactcaaa ccatttattg cttaaaaaat     2700

agcttacgcc atgctatgct ataagcagct tttatgcaca ttgacaaatg aagagtaagc     2760

ttcagcttgc taaaggaaac tgtggaacct tttgtaactt ttggtgatat ggaaaattat     2820

ttacaaaccg tcaaagaata tgaggaagtt gctgtatgac atagtgctgg cactgatatt     2880

atccatcatc tctttttgga cacttctgta aatgtgattg gattgtttga aagaagattt     2940

aaagtttcaa agttttttgt tctgtttttg ctttgcattt ggagaaaata ttgaaagcag     3000

ggtatgttgt ttcattcacc ttgaaaaaac catgagtaaa tggggatata gaatctctga     3060

atagctcgct aaaagattca agcaagggac atgaattttg ttccatctat caataatatc     3120

cagaagaaca acttttttaa agagtctata gcaaaaagca aaaaaaaaaa aaaattctaa     3180

acacaaagtc aaaataaacc tattgtaaaa gcatttcgtg atgagcatga aaaagattgt     3240

ttaaagatga tccccccagc tacccatttt ccaaaactac acagatcaca gctcatttct     3300

ctaagtggag cagttatcaa gaaacccaaa caccaaaatt gctactcttc acatttaatc     3360

ctacaaaaag tactccaatt tcaaaatatg tatgtaacct gcgatttcaa tgattgttgt     3420

tcatatacat catgtattat tttggcccat tttgggccta aaaaagaaaa ctatgcctta     3480

aaaatcagaa ccttttctcc ccactatgct tatgtggcca tctacagcac ttagaataaa     3540

aacagatgtt aaaatattca gtgaaagttt tattggaaaa aggaattgag atatataatt     3600

gagatttggt gaaattgaag gagaaaattt aagtgagtct ttaaaatata ttctgaatga     3660

aaactgtatt gaggattcat ttttgttcct tttttttctt tttctctttt ctcctttttc     3720

ttctttttaa tagtctagtt ttagtcagtc agtgaggaag aattgggcca tgctaacgtt     3780

atcacaagag aacaatggca gaaatggtat tagttatata atatttaagg acaaactata     3840

tgttttgctg ttttaacgta gtgactcact gaactaaata cataattgac caacattaag     3900

tgtatttcca atacagaagg gttgaaaata ttacattata aactcttttg aaaaatgtat     3960

ctaaaatttt ttaagttctg ttttgattcc actttttggt tgagttttta tgtttttgtt     4020

ttcaggtaga ttaataaatc tggcagctga tttctgcaag attcttgtgt tttgaatttc     4080

tcattgaatt ggctactcaa acatagaaat catttgttaa tgatgtaatg tcttctctca     4140

gcttttatct tcactgctgt ttgctgtctc ttgatgatga catgttaata cccaatagat     4200

taattgcaac aaacacttat actcaaataa ctaagtaaaa ataatttttc ttgttatgtc     4260

catgaaaagt gcttcagaat aaaaatccac aagactgaca gtgcagaaca tttttctcaa     4320

atcatgggcg gatcttggag gtctagtttc ccgtagatgc tgtaaccaat taccacaact     4380

tcagtaattt acacaaattt atcttatagt tctggaggca gaagttcaaa agaagcctta     4440

agagactaaa accaagatgt ccttaggtct ggttccttct ggaggctcca ggggagattc     4500

ttccagcttt cacttctaga gtctgctgac attccttggc tcctggctac atcacttcaa     4560

tctctgcttc catggtcaca tactcttcta ctatagtcaa atttccttcc tgcctcttat     4620

aaggatgctt gtgattacat ttaggggatg ctcagataat ccaggacaat ctctccatct     4680

caagatcctt aacttaatga cgtgtgccaa gtccctttgg ctagataatt attcataggt     4740

cccagggatt aggacatgga tgtaaggggt gagggcaggg ctgttattca gaacaccgca     4800

cggaggagga agactgtgta gcaaagactc taattgattt actcaggaac agtggagttc     4860

tgctgaggga tctaggattt gaaagtacta gagtttgctt ttatttacca ctgagatatt     4920

ttccccttat tctgcataaa taattttgaa aactttctat attaaatttc aactattcca     4980

ctaaaatgtc tggtaatcac atcaagcctt tagattattc aaatccttcc ccagccccca     5040

ggaaaacact aagtcatgaa acagaaaaac agaaggtatg ataataatag taataacagt     5100

taaatcagtg gtctaatcca gattttattt tttaatacat ttcttttggt gttaatatgg     5160

gttactatgt gatcttatca tttgctagtg attattactt attaggtaag aacaatgtgt     5220

aaaatatgtc tattactcaa aagaacaatt gcaaaatgag tcaacttatc tttatataac     5280

caggaaagaa atatattgcc agaagctaca gaattttgcc agatgatagg gatttctaaa     5340

atgagccact ttgtctatca tgcagccttt tcagagcttg taatgagaaa acattacaga     5400

ggagaaggtc atttggatgt ttgttacttg gaatcctaga aaacaaaaac taaaatttaa     5460

aaataagaag tgagtaagct attttccatt tgcgatttgg tatggagaag agaggaaata     5520

gaattattaa aaaaatacaa attgggtaaa agtgatggtg gaaaaaatat aaagaaggca     5580

aatgtacata ttaagcaatt ctactaagaa ttggaaaaat caagtttcaa aaagatggta     5640

atagttgggc atgatactag aaaatttcac ccagtttatt cagagctcaa ctagtacttt     5700

taggacttct ttttttatat acatgagact cactttgaca tacttaaaaa aaaaacagtt     5760

tatggaaagt acagtttaag aggagaattt gattagacta agtggatatc tttatagaaa     5820

tattaatgat ttcagaattt tcagttacaa gtgtatatac cgtggctatt gtttatggat     5880

tcatatgtaa ggtagggtct tttttgcata tagactccag tattagttac tttcattcta     5940

aaattatatt tatgcttcta tggggaagaa aatttttaat tcacttggtt gtattaaaat     6000

tatacttacg gtttgagaaa acatgctatg aaaatcatga ttatagcaaa ttaaatatgc     6060

tcaaaattta aatctaaaat aaaagcccag aaactgaaaa aaaaaaaaaa aaaa           6114


<210>  1270
<211>  5696
<212>  DNA
<213>  homo sapiens

<400>  1270
acaagtgacg ccgccggccc ccgcgccgcg cctccccctc ctcacggctc ccgcccctcc       60

gcccgctccg ccgctctagc tccgcgctcc gccaccctcg cgcccgccag ccccgcaact      120

tcaccccgcg cgccgcagct gctgcgagcg gacgcggcag ggcagccggc gctggggaca      180

gctcgcgtcc acccgacttc ctcccggggt ccccttcacc caagtgagcc agctcaggct      240

gtctgcaaag ccggaggtgc gggcagctcc gggcattgca ttggtgcgga ggcttttata      300

tgccagagaa ccctgagtgt gcccctgaca tgacaaggag ccgtcgtcgt taggactacc      360

gaccagactc ccggaaatca tgttggtagg atcccagtct ttttcgcctg gagggcccaa      420

tgggatcatt agaagccagt cctttgcggg tttcagcggc ctccaggaaa ggcgatccag      480

gtgtaactcc ttcattgaaa attcctccgc tctcaagaag cctcaggcca aactgaagaa      540

aatgcacaat ttaggccaca aaaacaacaa tccccccaaa gagcctcagc ctaaaagggt      600

ggaagaagtc tacagggcct tgaaaaatgg acttgatgaa tatctggagg ttcaccagac      660

ggagctggac aagttgacag ctcagttaaa agatatgaaa agaaactctc gcctgggtgt      720

actgtatgac ctagacaagc aaattaaaac aattgaaaga tacatgagac gcctggagtt      780

tcatataagt aaggtagatg aactctatga agcttattgt atccagcgac gcctccagga      840

tggtgccagc aaaatgaagc aagccttcgc aacatcccct gccagcaaag ctgcccggga      900

gagtctgaca gagatcaatc ggagcttcaa ggagtacaca gagaatatgt gcaccattga      960

agtggagcta gagaatctgc tgggagaatt ctccatcaag atgaaaggtc tggctggctt     1020

tgcacgcctc tgtcctggag atcaatatga aattttcatg aagtatggcc ggcagcggtg     1080

gaaactgaaa ggcaaaatag aagtaaatgg caagcagagc tgggatggag aagaaacagt     1140

ttttctgccc ctgatagttg ggttcatctc catcaaggtc acggagctca aagggctagc     1200

aactcacatc ctggtaggta gcgtgacctg tgagaccaaa gagctgtttg cagcccgacc     1260

tcaggtagtg gctgtcgaca tcaatgacct tggtaccatc aaactgaacc tggaaatcac     1320

ctggtatcca tttgacgtgg aggacatgac cgcatcctca ggcgctggga acaaggcagc     1380

agcccttcag aggagaatgt ccatgtacag ccagggtacc ccggaaacgc ccaccttcaa     1440

agaccactcc ttctttaggt ggctgcatcc ttccccagac aagcccaggc ggctgtctgt     1500

cttgagtgcc ttgcaagaca ctttctttgc caagctgcac cgcagccgct ccttcagtga     1560

cctgccctcc ctcaggccga gtcccaaggc cgtgctagag ctctattcaa atctacctga     1620

tgacatcttt gaaaatggaa aggcagccga ggagaaaatg ccactgtcgc tcagcttcag     1680

tgacctgccc aacggggact gcgccctcac ctcccactca acaggctccc cttccaactc     1740

aacaaatcca gaaattacca tcacccctgc ggagtttaac ctcagcagct tggcctccca     1800

gaatgagggt atggatgaca ccagctcagc atcttccagg aactccctgg gagaaggcca     1860

agagccaaag tcacacctga aggaggaaga cccagaggag cccagaaaac ctgcctcggc     1920

cccatctgag gcttgccgcc gacagtcctc aggtgctggg gctgagcacc tgttccttga     1980

gaatgatgtt gcagaagcac ttctgcaaga gtctgaggag gcctctgagc tcaagcctgt     2040

ggaactggac acttcggaag gaaacatcac aaagcagctg gtcaagaggc tcacatctgc     2100

agaggtgcca atggccacag acaggctgct ctctgagggt tctgttggtg gagaatctga     2160

aggctgcaga tcctttctag atggaagctt agaggatgct tttaatgggc ttttacttgc     2220

attagaacca cataaagagc agtataaaga gtttcaggat ctgaaccaag aagtcatgaa     2280

tttggatgat attctaaaat gcaagccagc agtaagccgc agcaggtctt ccagtttaag     2340

tctcacagtt gaaagtgctt tagaaagctt tgatttcctg aacacctctg attttgacga     2400

ggaggaggat ggtgatgagg tttgtaatgt tggcggaggt gctgactcag tattttcaga     2460

cactgagact gagaaacaca gttacaggtc ggttcaccca gaagccaggg ggcatctcag     2520

tgaagcgctc actgaagaca caggagttgg gaccagtgtg gcaggaagtc ctctcccact     2580

gaccacaggc aacgagagcc tggacatcac catcgtcagg cacctccagt actgcaccca     2640

actcgtgcag caaattgttt tctcaagcaa aaccccattt gtggcaagaa gtctcttaga     2700

gaagctttct aggcagatcc aagtgatgga gaaactcgca gctgtcagtg atgagaacat     2760

aggaaatatc agttctgttg tggaagccat accagaattt cacaaaaagc tgtctttgct     2820

gtcattctgg accaagtgct gcagccctgt tggtgtctac cacagcccag cggacagagt     2880

gatgaagcag ctggaggcca gctttgccag aactgtcaac aaagaatatc caggacttgc     2940

agacccagtg tttcgaaccc tggtgtccca aattctggac cgggctgagc ctctgctttc     3000

ctccagcctg tcctcggaag tcgtcactgt tttccagtat tacagttact tcaccagcca     3060

cggcgtcagt gacctggaga gttacctgag ccagctggcc aggcaagttt ccatggttca     3120

gactctgcaa tcactaagag atgaaaaact gctacaaacc atgagtgacc ttgctcccag     3180

caacctcctg gcccagcagg aagtactcag gactctggct ctgctattaa ccagagagga     3240

caacgaagtt agcgaggctg tgacgcttta cttggcagca gcctccaaaa atcagcattt     3300

cagggaaaag gccttgctct attactgtga agcactaaca aagacaaacc tccagctcca     3360

gaaagcagct tgcctggctc tgaaaatcct tgaggctact gaaagcatta aaatgctggt     3420

gacattgtgt caatctgata ctgaagaaat cagaaatgtg gcctcagaaa ccctcttgtc     3480

tctgggagaa gatgggcggc tggcatatga acaattggac aaatttcctc gagactgtgt     3540

taaagtcgga ggtcgtcatg gaactgaagt tgccacagcc ttttaattac aggttaactg     3600

cctaacagct gtcttaatat ctggcccttt tcatcaggat ggtgctgtgg tttgggctgg     3660

aaattgttta gagcctgaga gacacgacaa ctgaaataaa aatgtaggcc aggtgcagtg     3720

gctcatgcct gtaatcccag tactttggga ggccaacgca ggagaattgc ttaagcccag     3780

gaggttcaag accaacctgg gcaacatagc aaggccctgt ctctacaaaa aaaatagttt     3840

aattagtcag gcgtggtggc atgcacctgt agtcccagct acttgggagg ctaaggtggg     3900

aggattgctt gagcccagaa gattcaggct gcagtgagcc ataattgccc cactgcactc     3960

cagactgggt gacagagcaa aaccctgtct caaaaaacaa aacaacaaca acaactaaaa     4020

aaacatgtta tagaaagaat tcagagtctc gtttcacagt acctatctac ttttcctttg     4080

gccaatatag aatagggcta tggtataatt caaatatatt acatcgtcga ttgtgtctaa     4140

taatactcag tgaaagagtc catcttatct taatatgtat gaaatttaaa aatagccatc     4200

tttgtacttt tttgcaagtt tctctataag cttgaaatag tcatgtgata cttcgacaaa     4260

catcatatgc cttgcagttt ttctcggtcg tgttctcagg gttgagtagt ccccttagct     4320

acctaacttt actttcaata caaagcacaa aaaagaatat cttcaaataa aagtttgcct     4380

gcagaacctg gcaaaatgac ccattaggag agtttagatg ttttaatttt atgtgctccc     4440

agctactctg gagtctgagg tgggaggatc acttgaggca gaggttgcag taagctgaga     4500

ttacactact gcactccagc ccatgtgaca gaggaatgag agccagtctc aaaaaaaaaa     4560

acaaaaaact cccataattt attttgtttc ttttccccat cctgaaaatt cccaaatcat     4620

gtttccatta tggaaaaatg ataagtaaat gactaagaac tacattaaga ttatgcctat     4680

acacttaaac aaaaaactca aagcttatgc tttttttttt ttaattaatg agagctattt     4740

tttatgatat tcttaccata ggggtgtttt gctgctaaga caaatcaaaa ccaaaagctg     4800

tagattcaca aacctgtgat gctctttgag gtggaggaac ctagaagtca gagaaatcct     4860

aatggagtag gagtggagga acatttaaag tggtccctcc ttctgtaaaa atgaccgtgg     4920

gattagaaag aaggacatcc tgaggggtgg ttactgcccc cagggaaatc actcactggt     4980

aggattccct ggccaaatag ttcaaacatc aggtcccatt attgcttcag tatcagagat     5040

gcaagttcat taagcaaagt acaagaccat tcagtagctc ttattaaaat atcttttctt     5100

cctctaaaga gtgtacaagg tggggtatgc caaggtatca aaacaatata tgtgagtgta     5160

atttaaactg tggaatatca actgtactat ggacgtgttt gtatcattta gatgtcattt     5220

taaatattta cattttagca agacttttaa aaaggactca tttcatttca aagtgcaaat     5280

tgtttgccag gcttctggca aatggttctt tcaactgtga acttatcgtg tacatatctg     5340

tatatttata aatattatat atattcatac atccttcact ttaaaggtac attgtacagt     5400

ctgtagttag gaggtatagc ctatagctta tgttaaatgg ttgaaatggt tctttttata     5460

gaaagtcaaa cacagatgtt acaggatttt gtgtttggtt tgtcattttt ttatttttta     5520

ttttgactat tgcatgagta attaattcca gatcttttgt attcacttct gtattttatg     5580

tttggttgag gggtgctttt agttgtgtgg catttgtatt cattgatctt tcagtcatgt     5640

aagttaaaat aaaaattatt tttgaattac tagcatcaaa aaaaaaaaaa aaaaaa         5696


<210>  1271
<211>  2445
<212>  DNA
<213>  homo sapiens

<400>  1271
aaagcagcca atgggagagc cgaggcgggg aggtgcggcc aatggcgcgg gcctgtttga       60

ttcaaaggtt gcctataaag cgggactgca cgccggtttt tgtccgaggg ctgtcgagtc      120

cgagcgccgc catggctctg ctgtccgagg gcctggacga ggtgcccgcc gcctgcctgt      180

cgccgtgcgg gccgcccaac ccgaccgagc tgttcagcga gtcacggcgc ctggctctgg      240

aggagctggt ggcgggcggc cccgaagcct tcgcggcctt cctgcgacgc gagcgcctgg      300

ctcgtttcct gaaccccgat gaggtgcacg ccattctgcg cgcggcggag aggccgggag      360

aggagggcgc ggcggcggcg gcggcggccg aggactcgtt cggctcctcg cacgactgct      420

cttcgggcac ctacttcccc gagcagtcgg acctggagcc accgctgttg gagcttggct      480

ggcccgcctt ctaccagggc gcctaccgcg gcgccacgcg tgtcgagacg cacttccagc      540

cccgcggcgc tggcgaaggt ggcccctacg gctgcaagga cgctctgcgc cagcagctcc      600

gctcggcgcg agaggtgatt gcagtggtca tggacgtgtt cacagacatc gacatcttca      660

gagacctgca agaaatatgc aggaaacagg gagttgctgt gtatatcctt ctggaccagg      720

ctctcctctc tcaatttctg gatatgtgca tggatctgaa agttcatcct gaacaggaaa      780

agttaatgac agttcggact atcacaggaa atatctacta tgcaaggtca ggaactaaga      840

ttattgggaa ggttcacgaa aagttcacgt tgattgatgg catccgcgtg gcaacaggct      900

cctacagttt tacatggacg gatggcaaat taaacagcag taacttggta attctgtctg      960

gccaagtggt tgaacacttt gatctggagt tccgaatcct gtatgcccag tccaagccca     1020

tcagccccaa actcctgtct cacttccaga gcagcaacaa gtttgatcac ctcaccaacc     1080

gaaaaccaca gtccaaggag ctcaccctgg gcaacctgct gcggatgcgg ctggctaggc     1140

tgtcaagtac tcccaggaag gcggacctgg acccagagat gcccgcagag ggcaaggcag     1200

agcgcaagcc ccatgactgt gagtcctcta ctgttagtga ggaagactac ttcagcagcc     1260

acagggacga gctccagagc agaaaggcca ttgacgctgc cactcaaaca gagccaggag     1320

aggagatgcc agggctgagt gtgagtgagg tgggaacaca aaccagcatc accacagcat     1380

gtgctggtac ccagactgca gtcatcacca ggatagcaag ctctcaaacc acgatttggt     1440

ccagatcgac cactactcag actgacatgg atgagaacat tctctttcct cgaggaactc     1500

aatctacaga agggtcacca gtctcaaaaa tgtctgtatc gagatcttcc agtttgaagt     1560

cttcctcctc tgtgtcttcc caaggctctg tggcaagctc cactggttct cccgcttcca     1620

tcagaaccac tgacttccac aatcctggct atcccaagta cctgggcacc ccccacctgg     1680

aactgtactt gagtgactca cttagaaact tgaacaaaga gcggcaattc cacttcgctg     1740

gtatcaggtc ccggctcaac cacatgctgg ctatgctgtc aaggagaaca ctctttactg     1800

aaaaccacct tggccttcat tctggcaatt tcagcagagt taatttgctt gctgttagag     1860

atgtagcact ttatccttcc tatcagtaac tgctccgtgt tcagactcct ggtttcttcc     1920

aggcttacag tggacatcat cagcttcctg ctttaaaaaa tatcttatgt ccctaattgc     1980

ctttctttta cctgactttg tcacctttgt tgtctttgaa ttctttaggc tgcatattat     2040

tttacatgct ttgttttgtc atgtatatac caggtattgg ttttatggtt taaacactat     2100

ggatacaggg gtttgttttg cacaatttta atagtcatgc actacataat gatgttttgg     2160

tcaatgacag accacgtata tgttggcagt ctcataagat tataatactg tatttttact     2220

ataccttttc tgtgtttaga tacaaatacc attatgttac agttgcctac agtattcagt     2280

gcagtaacat gatgtacagg tttgtagcct gttttgcatt tttcttaggt tgtatgctct     2340

tctgttttaa aggtttgaat caccagcatt tttgtgatca aaatcctatt tagaaaaaat     2400

aaaactactt tctgtttatc tctttagaaa aaaaaaaaaa aaaaa                     2445


<210>  1272
<211>  8789
<212>  DNA
<213>  homo sapiens

<400>  1272
atgctcagtg gcttctcgac aagttggcag caacaacacg gccctggtcg tcgtcgccgc       60

tgcggtaacg gagcggtttg ggtggcggag cctgcgttcg cgccttcccg ctctcctcgg      120

gaggcccttc ctgctctccc ctaggctccg cggccgccca gggggtggga gcgggtgagg      180

ggagccaggc gcccagcgag agaggccccc cgccgcaggg cggcccggga gctcgaggcg      240

gtccggcccg cgcgggcagc ggcgcggcgc tgaggagggg cggcctggcc gggacgcctc      300

ggggcggggg ccgaggagct ctccgggccg ccggggaaag ctacgggccc ggtgcgtccg      360

cggaccagca gcgcgggaga gcggactccc ctcgccaccg cccgagccca ggttatcctg      420

aatacatgtc taacaatttt ccttgcaacg ttagctgttg tttttcactg tttccaaagg      480

atcaaaattg cttcagaaat tggagacata tttgatttaa aaggaaaaac ttgaacaaat      540

ggacaatatg tctattacga atacaccaac aagtaatgat gcctgtctga gcattgtgca      600

tagtttgatg tgccatagac aaggtggaga gagtgaaaca tttgcaaaaa gagcaattga      660

aagtttggta aagaagctga aggagaaaaa agatgaattg gattctttaa taacagctat      720

aactacaaat ggagctcatc ctagtaaatg tgttaccata cagagaacat tggatgggag      780

gcttcaggtg gctggtcgga aaggatttcc tcatgtgatc tatgcccgtc tctggaggtg      840

gcctgatctt cacaaaaatg aactaaaaca tgttaaatat tgtcagtatg cgtttgactt      900

aaaatgtgat agtgtctgtg tgaatccata tcactacgaa cgagttgtat cacctggaat      960

tgatctctca ggattaacac tgcagagtaa tgctccatca agtatgatgg tgaaggatga     1020

atatgtgcat gactttgagg gacagccatc gttgtccact gaaggacatt caattcaaac     1080

catccagcat ccaccaagta atcgtgcatc gacagagaca tacagcaccc cagctctgtt     1140

agccccatct gagtctaatg ctaccagcac tgccaacttt cccaacattc ctgtggcttc     1200

cacaagtcag cctgccagta tactgggggg cagccatagt gaaggactgt tgcagatagc     1260

atcagggcct cagccaggac agcagcagaa tggatttact ggtcagccag ctacttacca     1320

tcataacagc actaccacct ggactggaag taggactgca ccatacacac ctaatttgcc     1380

tcaccaccaa aacggccatc ttcagcacca cccgcctatg ccgccccatc ccggacatta     1440

ctggcctgtt cacaatgagc ttgcattcca gcctcccatt tccaatcatc ctgctcctga     1500

gtattggtgt tccattgctt actttgaaat ggatgttcag gtaggagaga catttaaggt     1560

tccttcaagc tgccctattg ttactgttga tggatacgtg gacccttctg gaggagatcg     1620

cttttgtttg ggtcaactct ccaatgtcca caggacagaa gccattgaga gagcaaggtt     1680

gcacataggc aaaggtgtgc agttggaatg taaaggtgaa ggtgatgttt gggtcaggtg     1740

ccttagtgac cacgcggtct ttgtacagag ttactactta gacagagaag ctgggcgtgc     1800

acctggagat gctgttcata agatctaccc aagtgcatat ataaaggtct ttgatttgcg     1860

tcagtgtcat cgacagatgc agcagcaggc ggctactgca caagctgcag cagctgccca     1920

ggcagcagcc gtggcaggaa acatccctgg cccaggatca gtaggtggaa tagctccagc     1980

tatcagtctg tcagctgctg ctggaattgg tgttgatgac cttcgtcgct tatgcatact     2040

caggatgagt tttgtgaaag gctggggacc ggattaccca agacagagca tcaaagaaac     2100

accttgctgg attgaaattc acttacaccg ggccctccag ctcctagacg aagtacttca     2160

taccatgccg attgcagacc cacaaccttt agactgaggt cttttaccgt tggggccctt     2220

aaccttatca ggatggtgga ctacaaaata caatcctgtt tataatctga agatatattt     2280

cacttttgtt ctgctttatc ttttcataaa gggttgaaaa tgtgtttgct gccttgctcc     2340

tagcagacag aaactggatt aaaacaattt tttttttcct cttcagaact tgtcaggcat     2400

ggctcagagc ttgaagatta ggagaaacac attcttatta attcttcacc tgttatgtat     2460

gaaggaatca ttccagtgct agaaaattta gccctttaaa acgtcttaga gccttttatc     2520

tgcagaacat cgatatgtat atcattctac agaataatcc agtattgctg attttaaagg     2580

cagagaagtt ctcaaagtta attcacctat gttattttgt gtacaagttg ttattgttga     2640

acatacttca aaaataatgt gccatgtggg tgagttaatt ttaccaagag taactttact     2700

ctgtgtttaa aaagtaagtt aataatgtat tgtaatcttt catccaaaat attttttgca     2760

agttatatta gtgaagatgg tttcaattca gattgtcttg caacttcagt tttatttttg     2820

ccaaggcaaa aaactcttaa tctgtgtgta tattgagaat cccttaaaat taccagacaa     2880

aaaaatttaa aattacgttt gttattccta gtggatgact gttgatgaag tatacttttc     2940

ccctgttaaa cagtagttgt attcttctgt atttctaggc acaaggttgg ttgctaagaa     3000

gcctataaga ggaatttctt ttccttcatt catagggaaa ggttttgtat tttttaaaac     3060

actaaaagca gcgtcactct acctaatgtc tcactgttct gcaaaggtgg caatgcttaa     3120

actaaataat gaataaactg aatattttgg aaactgctaa attctatgtt aaatactgtg     3180

cagaataatg gaaacattac agttcataat aggtagtttg gatatttttg tacttgattt     3240

gatgtgactt tttttggtat aatgtttaaa tcatgtatgt tatgatattg tttaaaattc     3300

agtttttgta tcttggggca agactgcaaa cttttttata tcttttggtt attctaagcc     3360

ctttgccatc aatgatcata tcaattggca gtgactttgt atagagaatt taagtagaaa     3420

agttgcagat gtattgactg taccacagac acaatatgta tgctttttac ctagctggta     3480

gcataaataa aactgaatct caacatacaa agttgaattc taggtttgat ttttaagatt     3540

ttttttttct tttgcacttt tgagtccaat ctcagtgatg aggtaccttc tactaaatga     3600

caggcaacag ccagttctat tgggcagctt tgtttttttc cctcacactc taccgggact     3660

tccccatgga cattgtgtat catgtgtaga gttggttttt ttttttttta atttttattt     3720

tactatagca gaaatagacc tgattatcta caagatgata aatagattgt ctacaggata     3780

aatagtatga aataaaatca aggattatct ttcagatgtg tttacttttg cctggagaac     3840

ttttagctat agaaacactt gtgtgatgat agtcctcctt atatcacctg gaatgaacac     3900

agcttctact gccttgctca gaaggtcttt taaatagacc atcctagaaa ccactgagtt     3960

tgcttatttc tgtgatttaa acatagatct tgatccaagc tacatgactt ttgtctttaa     4020

ataacttatc taccacctca tttgtactct tgattactta caaattcttt cagtaaacac     4080

ctaattttct tctgtaaaag tttggtgatt taagttttat tggcagtttt ataaaaagac     4140

atcttctcta gaaattgcta actttaggtc cattttactg tgaatgagga ataggagtga     4200

gttttagaat aacagatttt taaaaatcca gatgatttga ttaaaacctt aatcatacat     4260

tgacataatt cattgcttct tttttttgag atatggagtc ttgctgtgtt gcccaggcag     4320

gagtgcagtg gtatgatctc agctcactgc aacctctgcc tcccgggttc aactgattct     4380

cctgcctcag cctccctggt agctaggatt acaggtgccc gccaccatgc ctggctaact     4440

tttgtagttt tagtagagac ggggttttgc ctgttggcca ggctggtctt gaactcctga     4500

cctcaagtga tccatccacc ttggcctccc aaagtgctgg gattacgggc gtgagccact     4560

gtccctggcc tcattgttcc cttttctact ttaaggaaag ttttcatgtt taatcatctg     4620

gggaaagtat gtgaaaaata tttgttaaga agtatctctt tggagccaag ccacctgtct     4680

tggtttcttt ctactaagag ccataaagta tagaaatact tctagttgtt aagtgcttat     4740

atttgtacct agatttagtc acacgctttt gagaaaacat ctagtatgtt atgatcagct     4800

attcctgaga gcttggttgt taatctatat ttctatttct tagtggtagt catctttgat     4860

gaataagact aaagattctc acaggtttaa aattttatgt ctactttaag ggtaaaatta     4920

tgaggttatg gttctgggtg ggttttctct agctaattca tatctcaaag agtctcaaaa     4980

tgttgaattt cagtgcaagc tgaatgagag atgagccatg tacacccacc gtaagacctc     5040

attccatgtt tgtccagtgc ctttcagtgc attatcaaag ggaatccttc atggtgttgc     5100

ctttattttc cggggagtag atcgtgggat atagtctatc tcatttttaa tagtttaccg     5160

cccctggtat acaaagataa tgacaataaa tcactgccat ataaccttgc tttttccaga     5220

aacatggctg ttttgtattg ctgtaaccac taaataggtt gcctatacca ttcctcctgt     5280

gaacagtgca gatttacagg ttgcatggtc tggcttaagg agagccatac ttgagacatg     5340

tgagtaaact gaactcatat tagctgtgct gcatttcaga cttaaaatcc atttttgtgg     5400

ggcagggtgt ggtgtgtaaa ggggggtgtt tgtaatacaa gttgaaggca aaataaaatg     5460

tcctgtctcc cagatgatat acatcttatt atttttaaag tttattgcta attgtaggaa     5520

ggtgagttgc aggtatcttt gactatggtc atctggggaa ggaaaatttt acattttact     5580

attaatgctc cttaagtgtc tatggaggtt aaagaataaa atggtaaatg tttctgtgcc     5640

tggtttgatg gtaactggtt aatagttact caccatttta tgcagagtca cattagttca     5700

caccctttct gagagccttt tgggagaagc agttttattc tctgagtgga acagagttct     5760

ttttgttgat aatttctagt ttgctccctt cgttattgcc aactttactg gcattttatt     5820

taatgatagc agattgggaa aatggcaaat ttaggttacg gaggtaaatg agtatatgaa     5880

agcaattacc tctaaagcca gttaacaatt attttgtagg tggggtacac tcagcttaaa     5940

gtaatgcatt tttttttccc gtaaaggcag aatccatctt gttgcagata gctatctaaa     6000

taatctcata tcctcttttg caaagactac agagaatagg ctatgacaat cttgttcaag     6060

cctttccatt tttttccctg ataactaagt aatttctttg aacataccaa gaagtatgta     6120

aaaagtccat ggccttattc atccacaaag tggcatccta ggcccagcct tatccctagc     6180

agttgtccca gtgctgctag gttgcttatc ttgtttatct ggaatcactg tggagtgaaa     6240

ttttccacat catccagaat tgccttattt aagaagtaaa acgttttaat ttttagcctt     6300

tttttggtgg agttatttaa tatgtatatc agaggatata ctagatggta acatttcttt     6360

ctgtgcttgg ctatctttgt ggacttcagg ggcttctaaa acagacagga ctgtgttgcc     6420

tttactaaat ggtctgagac agctatggtt ttgaattttt agtttttttt ttttaaccca     6480

cttcccctcc tggtctcttc cctctctgat aattaccatt catatgtgag tgttagtgtg     6540

cctcctttta gcattttctt cttctctttc tgattcttca tttctgactg cctaggcaag     6600

gaaaccagat aaccaaactt actagaacgt tctttaaaac acaagtacaa actctgggac     6660

aggacccaag acactttcct gtgaagtgct gaaaaagacc tcattgtatt ggcatttgat     6720

atcagtttga tgtagcttag agtgcttcct gattcttgct gagtttcagg tagttgagat     6780

agagagaagt gagtcatatt catattttcc cccttagaat aatattttga aaggtttcat     6840

tgcttccact tgaatgctgc tcttacaaaa actggggtta caagggttac taaattagca     6900

tcagtagcca gaggcaatac cgttgtctgg aggacaccag caaacaacac acaacaaagc     6960

aaaacaaacc ttgggaaact aaggccattt gttttgtttt ggtgtcccct ttgaagccct     7020

gccttctggc cttactcctg tacagatatt tttgacctat aggtgccttt atgagaattg     7080

agggtctgac atcctgcccc aaggagtagc taaagtaatt gctagtgttt tcagggattt     7140

taacatcaga ctggaatgaa tgaatgaaac tttttgtcct ttttttttct gttttttttt     7200

ttctaatgta gtaaggacta aggaaaacct ttggtgaaga caatcatttc tctctgttga     7260

tgtggatact tttcacaccg tttatttaaa tgctttctca ataggtccag agccagtgtt     7320

cttgttcaac ctgaaagtaa tggctctggg ttgggccaga cagttgcact ctctagtttg     7380

ccctctgcca caaatttgat gtgtgacctt tgggcaagtc atttatcttc tctgggcctt     7440

agttgcctca tctgtaaaat gagggagttg gagtagatta attattccag ctctgaaatt     7500

ctaagtgacc ttggctacct tgcagcagtt ttggatttct tccttatctt tgttctgctg     7560

tttgaggggg ctttttactt atttccatgt tattcaaagg agactaggct tgatatttta     7620

ttactgttct tttatggaca aaaggttaca tagtatgccc ttaagactta attttaacca     7680

aaggcctagc accaccttag gggctgcaat aaacacttaa cgcgcgtgcg cacgcgcgcg     7740

cgcacacaca cacacacaca cacacacaca cacaggtcag agtttaaggc tttcgagtca     7800

tgacattcta gcttttgaat tgcgtgcaca cacacacgca cgcacacact ctggtcagag     7860

tttattaagg ctttcgagtc atgacattat agcttttgag ttggtgtgtg tgacaccacc     7920

ctcctaagtg gtgtgtgctt gtaatttttt ttttcagtga aaatggattg aaaacctgtt     7980

gttaatgctt agtgatatta tgctcaaaac aaggaaattc ccttgaaccg tgtcaattaa     8040

actggtttat atgactcaag aaaacaatac cagtagatga ttattaactt tattcttggc     8100

tctttttagg tccattttga ttaagtgact tttggctgga tcattcagag ctctcttcta     8160

gcctaccctt ggatgagtac aattaatgaa attcatattt tcaaggacct gggagccttc     8220

cttggggctg ggttgagggt ggggggttgg ggagtcctgg tagaggccag ctttgtggta     8280

gctggagagg aagggatgaa accagctgct gttgcaaagg ctgcttgtca ttgatagaag     8340

gactcacggg cttggattga ttaagactaa acatggagtt ggcaaacttt cttcaagtat     8400

tgagttctgt tcaatgcatt ggacatgtga tttaagggaa aagtgtgaat gcttatagat     8460

gatgaaaacc tggtgggctg cagagcccag tttagaagaa gtgagttggg ggttggggac     8520

agatttggtg gtggtatttc ccaactgttt cctcccctaa attcagagga atgcagctat     8580

gccagaagcc agagaagagc cactcgtagc ttctgctttg gggacaactg gtcagttgaa     8640

agtcccagga gttcctttgt ggctttctgt atacttttgc ctggttaaag tctgtggcta     8700

aaaaatagtc gaacctttct tgagaactct gtaacaaagt atgtttttga ttaaaagaga     8760

aagccaacta aaaaaaaaaa aaaaaaaaa                                       8789


<210>  1273
<211>  4068
<212>  DNA
<213>  homo sapiens

<400>  1273
ggttggttct gagaaggctt caaggaatag gcagacattt cagcaaggct gctgaggaag       60

gataggctgt ggaaattagg atgcagcact cctgcccggg tcccgcctcg gggtcgccag      120

gccctgaacc ccaacgccgg cattagtcgc gcctgcgcac ggccctgtgg agccgcggag      180

gcaagggacg gagaacgggg cggaggcgga gtcagggcgc ccgcgcgtgg gccccgcccc      240

cttatgtcgg gtataaagcc cctcccgctc acagtttccc tagtcctcga aggctcggaa      300

gcccgtcacc atgtcgtgcg agtcgtctat ggttctcggg tactgggata ttcgtgggct      360

cctgactatg atcgaagcca atggctggat gtgaaattca agctagacct ggactttcct      420

aatctgccct acctcctgga tgggaagaac aagatcaccc agagcaatgc catcttgcgc      480

tacatcgctc gcaagcacaa catgtgtggt gagactgaag aagaaaagat tcgagtggac      540

atcatagaga accaagtaat ggatttccgc acacaactga taaggctctg ttacagctct      600

gaccacgaaa aactgaagcc tcagtacttg gaagagctac ctggacaact gaaacaattc      660

tccatgtttc tggggaaatt ctcatggttt gccggggaaa agctcacctt tgtggatttt      720

ctcacctatg atatcttgga tcagaaccgt atatttgacc ccaagtgcct ggatgagttc      780

ccaaacctga aggctttcat gtgccgtttt gaggctttgg agaaaatcgc tgcctactta      840

cagtctgatc agttctgcaa gatgcccatc aacaacaaga tggcccagtg gggcaacaag      900

cctgtatgct gagcaggagg cagacttgca gagcttgttt tgtttcatcc tgtccgtaag      960

gggtcagcgc tcttgctttg ctcttttcaa tgaatagcac ttatgttact ggtgtccagc     1020

tgagtttctc ttgggtataa aggctaaaag ggaaaaagga tatgtggaga atcatcaaga     1080

tatgaattga atcgctgcga tactggcatt tccctactcc ccaactgagt tcaagggctg     1140

taggttcatg cccaagccct gagagtgggt actagaaaaa acgagattgc acagttggag     1200

agagcaggtg tgttaaatgg gactggagtc cctgtgaaga ctgggtgagg ataacacaag     1260

taaaactgtg gtactgatgg acttaaccgg agttcggaaa ccgtcctgtg tacacatggg     1320

agtttagtgt gataaaggca gtatttcaga ctggtgggct agccaataga gttgggacaa     1380

ttgcttactc attaaaaata atagagcccc acttgacact attcactaaa attaatctgg     1440

aatttaaggc ccaacattaa acacaaagct gttgaaatat tgatgaaaat gtaagaattt     1500

ttgtgaccac ggggtaggag aagtttcttt aaagacgtaa aaagaaaaaa accataggct     1560

gctctgcctg tggagtagcc attctttatt cttttacttt ttaaaataat aacaatcaca     1620

aaggaaagat ttgccaattg aataggatca aattctacaa cttttcctaa ggcacccaca     1680

aataaatgac aagtgagaca aaaagcacta gtataaagat tatataaaga cctataaatc     1740

attaagacaa ctgagttttt aaaaatggac aaaatccatg aacaatttat aaaatagaaa     1800

tatagccaaa aatgtctaaa agatgtttat gatgtaagga attatcaatt acaacagtga     1860

gaaaccatat ttccttctat ccgatgagta aaaagtttct aaagtgttgg caaggcttag     1920

gaaagtgata tgcatttcct gctggtcaag ttgtaaatta gtatagctac tttggaggac     1980

aattgtaaaa tttaaatcat atcctatgac ccagcaattc catgctataa aaactcatcc     2040

atggccgggc ttggtggctc acgcctgtaa tcccagcact ttgggaggct gaggtgggca     2100

gatcacgagg tcaagagatc gagaccatcc tggccaacat gatgaaaccc cgtttctact     2160

aaaaatacaa aaattagctg ggcatggtgg catgtgccta tagtcccagc tactcaggag     2220

gctgaggcag gagaattgct tgaacctggg aggcagaggt tgcagtgagc cgagatcacg     2280

ccactgcact ccagcctggc tacagggcga gactctgtct caaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaac attcaaagag acatatacta agatgttcac tgtggcattg tctgtaatga     2400

caaataagtg gaaaccgtgt aaatacctgt caatactatg gagtaccatg tggcaacgga     2460

agaatgagac tgaactgtgt gaactaacat gcaaagatcc ccaaaacagg ccaggtgtgg     2520

ttgctcacag ctgtaataac aacaccttca gaggctgagg tgagaggatc agttgaggcc     2580

aggagtttaa gaccagcctg ggcaacatag tgagacccct gtctcccaaa aatttttttt     2640

aattagctgt gcgcaattgc tcatgcatag tcccagctac ccaggaggct gaggtgggag     2700

gatcacttga gcccaggaat ttgaagctgc agtgagctgt gttcttgcca ctgcactcca     2760

atctgggtga ctgagcaaga ccctgtctct taaaaaaata aaaaagatct ccaagcatag     2820

agaagagtct ggagggaaac accaaactca taacagtctt actgcaggca agtgggataa     2880

aggcccagac tccatggtgg aagttaaagg gcatttccaa gttaaggcta agacttgctt     2940

ttctaactaa gagaatgtgc tcatgcattg cttgtgtagt agaaactagt ttttagaaaa     3000

gaaagcaaac ttaagaaaca ctgactcctg tggagatgac ttggcaccac tctcctttca     3060

cagagcagag tctgaatagt cttcagagat aggcctgtgg gccagattgc catcccctat     3120

ggaccagaag ccaaggatct ctctagtgat ggtcagaggg cccaaatggc agggataccc     3180

agtgatgtca ggaggaatag tacagacaga aggtgctaag cagacaattc aactgccatg     3240

ttttgccacc ccctgtgagc agggattagg tgttcaggcc agtatcttgg gcatggggga     3300

gcctttggcc agaagaggta taaagctcag aagtttttca gtctgataac tattgatata     3360

atttccatag tgtgagggag cggtatgctc tacccttgtg tatttaaggc aggacagaga     3420

aattgaggat gcccctgggg ctagatcgat gatatgacca gaaatcaaaa agggaatgca     3480

ttatttattg ctgtgtaaca ctgttaagag aggaggtagt taagggatgg ataggcacat     3540

agagagggaa ggtctcagga gaagggatag aaaggaacta tgttcacaag aacaacggca     3600

agacagtgcc tatactgcct ctacagttaa taggaaaaac ggaagaagtt acccttaagc     3660

taggatgttg ctcagaagtg accatcccaa ctttggtgcg ggcacaataa atcagcctaa     3720

atgtccctaa tttaacccag ctcattataa tgtcattaaa catgacatta gcattgtggt     3780

tttagcaccc ccatgggttt tgcttaggca ctcatgggta ataaccaaga tggagtccct     3840

ttggcaaaac ttaggcatgc acagctgtag taccccaaga agaaaatgtt acttctctca     3900

tctgggcaaa acccacagaa gacttcccag cttctgccac ataaaagaca cagaacacag     3960

acgccttact ggcaacctgc tttcaagacc cctgtctttg ctgagagctt tcctttttcc     4020

caataaattc tactctgccc tactcactct caaaaaaaaa aaaaaaaa                  4068


<210>  1274
<211>  4068
<212>  DNA
<213>  homo sapiens

<400>  1274
ggttggttct gagaaggctt caaggaatag gcagacattt cagcaaggct gctgaggaag       60

gataggctgt ggaaattagg atgcagcact cctgcccggg tcccgcctcg gggtcgccag      120

gccctgaacc ccaacgccgg cattagtcgc gcctgcgcac ggccctgtgg agccgcggag      180

gcaagggacg gagaacgggg cggaggcgga gtcagggcgc ccgcgcgtgg gccccgcccc      240

cttatgtcgg gtataaagcc cctcccgctc acagtttccc tagtcctcga aggctcggaa      300

gcccgtcacc atgtcgtgcg agtcgtctat ggttctcggg tactgggata ttcgtgggct      360

cctgactatg atcgaagcca atggctggat gtgaaattca agctagacct ggactttcct      420

aatctgccct acctcctgga tgggaagaac aagatcaccc agagcaatgc catcttgcgc      480

tacatcgctc gcaagcacaa catgtgtggt gagactgaag aagaaaagat tcgagtggac      540

atcatagaga accaagtaat ggatttccgc acacaactga taaggctctg ttacagctct      600

gaccacgaaa aactgaagcc tcagtacttg gaagagctac ctggacaact gaaacaattc      660

tccatgtttc tggggaaatt ctcatggttt gccggggaaa agctcacctt tgtggatttt      720

ctcacctatg atatcttgga tcagaaccgt atatttgacc ccaagtgcct ggatgagttc      780

ccaaacctga aggctttcat gtgccgtttt gaggctttgg agaaaatcgc tgcctactta      840

cagtctgatc agttctgcaa gatgcccatc aacaacaaga tggcccagtg gggcaacaag      900

cctgtatgct gagcaggagg cagacttgca gagcttgttt tgtttcatcc tgtccgtaag      960

gggtcagcgc tcttgctttg ctcttttcaa tgaatagcac ttatgttact ggtgtccagc     1020

tgagtttctc ttgggtataa aggctaaaag ggaaaaagga tatgtggaga atcatcaaga     1080

tatgaattga atcgctgcga tactggcatt tccctactcc ccaactgagt tcaagggctg     1140

taggttcatg cccaagccct gagagtgggt actagaaaaa acgagattgc acagttggag     1200

agagcaggtg tgttaaatgg gactggagtc cctgtgaaga ctgggtgagg ataacacaag     1260

taaaactgtg gtactgatgg acttaaccgg agttcggaaa ccgtcctgtg tacacatggg     1320

agtttagtgt gataaaggca gtatttcaga ctggtgggct agccaataga gttgggacaa     1380

ttgcttactc attaaaaata atagagcccc acttgacact attcactaaa attaatctgg     1440

aatttaaggc ccaacattaa acacaaagct gttgaaatat tgatgaaaat gtaagaattt     1500

ttgtgaccac ggggtaggag aagtttcttt aaagacgtaa aaagaaaaaa accataggct     1560

gctctgcctg tggagtagcc attctttatt cttttacttt ttaaaataat aacaatcaca     1620

aaggaaagat ttgccaattg aataggatca aattctacaa cttttcctaa ggcacccaca     1680

aataaatgac aagtgagaca aaaagcacta gtataaagat tatataaaga cctataaatc     1740

attaagacaa ctgagttttt aaaaatggac aaaatccatg aacaatttat aaaatagaaa     1800

tatagccaaa aatgtctaaa agatgtttat gatgtaagga attatcaatt acaacagtga     1860

gaaaccatat ttccttctat ccgatgagta aaaagtttct aaagtgttgg caaggcttag     1920

gaaagtgata tgcatttcct gctggtcaag ttgtaaatta gtatagctac tttggaggac     1980

aattgtaaaa tttaaatcat atcctatgac ccagcaattc catgctataa aaactcatcc     2040

atggccgggc ttggtggctc acgcctgtaa tcccagcact ttgggaggct gaggtgggca     2100

gatcacgagg tcaagagatc gagaccatcc tggccaacat gatgaaaccc cgtttctact     2160

aaaaatacaa aaattagctg ggcatggtgg catgtgccta tagtcccagc tactcaggag     2220

gctgaggcag gagaattgct tgaacctggg aggcagaggt tgcagtgagc cgagatcacg     2280

ccactgcact ccagcctggc tacagggcga gactctgtct caaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaac attcaaagag acatatacta agatgttcac tgtggcattg tctgtaatga     2400

caaataagtg gaaaccgtgt aaatacctgt caatactatg gagtaccatg tggcaacgga     2460

agaatgagac tgaactgtgt gaactaacat gcaaagatcc ccaaaacagg ccaggtgtgg     2520

ttgctcacag ctgtaataac aacaccttca gaggctgagg tgagaggatc agttgaggcc     2580

aggagtttaa gaccagcctg ggcaacatag tgagacccct gtctcccaaa aatttttttt     2640

aattagctgt gcgcaattgc tcatgcatag tcccagctac ccaggaggct gaggtgggag     2700

gatcacttga gcccaggaat ttgaagctgc agtgagctgt gttcttgcca ctgcactcca     2760

atctgggtga ctgagcaaga ccctgtctct taaaaaaata aaaaagatct ccaagcatag     2820

agaagagtct ggagggaaac accaaactca taacagtctt actgcaggca agtgggataa     2880

aggcccagac tccatggtgg aagttaaagg gcatttccaa gttaaggcta agacttgctt     2940

ttctaactaa gagaatgtgc tcatgcattg cttgtgtagt agaaactagt ttttagaaaa     3000

gaaagcaaac ttaagaaaca ctgactcctg tggagatgac ttggcaccac tctcctttca     3060

cagagcagag tctgaatagt cttcagagat aggcctgtgg gccagattgc catcccctat     3120

ggaccagaag ccaaggatct ctctagtgat ggtcagaggg cccaaatggc agggataccc     3180

agtgatgtca ggaggaatag tacagacaga aggtgctaag cagacaattc aactgccatg     3240

ttttgccacc ccctgtgagc agggattagg tgttcaggcc agtatcttgg gcatggggga     3300

gcctttggcc agaagaggta taaagctcag aagtttttca gtctgataac tattgatata     3360

atttccatag tgtgagggag cggtatgctc tacccttgtg tatttaaggc aggacagaga     3420

aattgaggat gcccctgggg ctagatcgat gatatgacca gaaatcaaaa agggaatgca     3480

ttatttattg ctgtgtaaca ctgttaagag aggaggtagt taagggatgg ataggcacat     3540

agagagggaa ggtctcagga gaagggatag aaaggaacta tgttcacaag aacaacggca     3600

agacagtgcc tatactgcct ctacagttaa taggaaaaac ggaagaagtt acccttaagc     3660

taggatgttg ctcagaagtg accatcccaa ctttggtgcg ggcacaataa atcagcctaa     3720

atgtccctaa tttaacccag ctcattataa tgtcattaaa catgacatta gcattgtggt     3780

tttagcaccc ccatgggttt tgcttaggca ctcatgggta ataaccaaga tggagtccct     3840

ttggcaaaac ttaggcatgc acagctgtag taccccaaga agaaaatgtt acttctctca     3900

tctgggcaaa acccacagaa gacttcccag cttctgccac ataaaagaca cagaacacag     3960

acgccttact ggcaacctgc tttcaagacc cctgtctttg ctgagagctt tcctttttcc     4020

caataaattc tactctgccc tactcactct caaaaaaaaa aaaaaaaa                  4068


<210>  1275
<211>  3471
<212>  DNA
<213>  homo sapiens

<400>  1275
taaatggcag ccaatggagg gtggtgttgc gcggggctgg gattagggcc ggggcgaatg       60

gctggcaatc ttactgggat tacagaacaa agagcctccc cgcgctcccg ctctccgctc      120

ctctccccgc gccgccccgc cctccgccgc agcccgcgcc gggggtgggg gccgccgagc      180

gccagccccc cggccggccg attccccccc cgcgccccct ccccgcgcct ccctccccgc      240

cctcgccgcg ccgccgtcct cgcctccctc tgcctctcct tcccccattc tcccggatta      300

attaaggagg cagcggcagg aggctgagtc ctggccgcgg gccggggccg gggcgccgct      360

ggcaggagcg cttggggatc ctccaaggcg accatggcct tgctgggtaa gcgctgtgac      420

gtccccacca acggctgcgg acccgaccgc tggaactccg cgttcacccg caaagacgag      480

atcatcacca gcctcgtgtc tgccttagac tccatgtgct cagcgctgtc caaactgaac      540

gccgaggtgg cctgtgtcgc cgtgcacgat gagagcgcct ttgtggtggg cacagagaag      600

gggagaatgt tcctgaatgc ccggaaggag ctacagtcag acttcctcag gttctgccga      660

gggcccccgt ggaaggatcc ggaggcagag caccccaaga aggtgcagcg gggcgagggt      720

ggaggccgta gcctccctcg gtcctccctg gaacatggct cagatgtgta ccttctgcgg      780

aagatggtag aggaggtgtt tgatgttctt tatagcgagg ccctgggaag ggccagtgtg      840

gtgccactgc cctatgagag gctgctcagg gagccagggc tgctggccgt gcaggggctg      900

cccgaaggcc tggccttccg aaggccagcc gagtatgacc ccaaggccct catggccatc      960

ctggaacaca gccaccgcat ccgcttcaag ctcaagaggc cacttgagga tggcgggcgg     1020

gactcgaagg ccctggtgga gctgaacggt gtctccctga ttcccaaggg gtcacgggac     1080

tgtggcctgc atggccaggc ccccaaggtg ccaccccagg acctgccccc aaccgccacc     1140

tcctcctcca tggccagctt cctgtacagc acggcgctcc ccaaccacgc catccgagag     1200

ctcaagcagg aagcaccttc ctgccccctt gcccccagcg acctgggcct gagtcggccc     1260

atgccagagc ccaaggccac cggtgcccaa gacttctccg actgttgtgg acagaagccc     1320

actgggcctg gtgggcctct catccagaac gtccatgcct ccaagcgcat tctcttctcc     1380

atcgtccatg acaagtcaga gaagtgggac gccttcataa aggaaaccga ggacatcaac     1440

acgctccggg agtgtgtgca gatcctgttt aacagcagat atgcggaagc cctgggcctg     1500

gaccacatgg tccccgtgcc ctaccggaag attgcctgtg acccggaggc tgtggagatc     1560

gtgggcatcc cggacaagat ccccttcaag cgcccctgca cttatggagt ccccaagctg     1620

aagcggatcc tggaggagcg ccatagtatc cacttcatca ttaagaggat gtttgatgag     1680

cgaattttca cagggaacaa gtttaccaaa gacaccacga agctggagcc agccagcccg     1740

ccagaggaca cctctgcaga ggtctctagg gccaccgtcc ttgaccttgc tgggaatgct     1800

cggtcagaca agggcagcat gtctgaagac tgtgggccag gaacctccgg ggagctgggc     1860

gggctgaggc cgatcaaaat tgagccagag gatctggaca tcattcaggt caccgtccca     1920

gacccctcgc caacctctga ggaaatgaca gactcgatgc ctgggcacct gccatcggag     1980

gattctggtt atgggatgga gatgctgaca gacaaaggtc tgagtgagga cgcgcggccc     2040

gaggagaggc ccgtggagga cagccacggt gacgtgatcc ggcccctgcg gaagcaggtg     2100

gagctgctct tcaacacacg atacgccaag gccattggca tctcggagcc cgtcaaggtg     2160

ccgtactcca agtttctgat gcacccggag gagctgtttg tggtgggact gcctgaaggc     2220

atctccctcc gcaggcccaa ctgcttcggg atcgccaagc tccggaagat tctggaggcc     2280

agcaacagca tccagtttgt catcaagagg cccgagctgc tcactgaggg agtcaaagag     2340

cccatcatgg atagtcaagg aactgcctcc tcacttggct tctctccccc tgccctgccc     2400

ccagagaggg attccgggga ccctctggtg gacgagagcc tgaagagaca gggctttcaa     2460

gaaaattatg acgcgaggct ctcacggatc gacatcgcca acacactaag ggagcaggtc     2520

caggaccttt tcaataagaa atacggggaa gccttgggca tcaagtaccc ggtccaggtc     2580

ccctacaagc ggatcaagag taaccccggc tccgtgatca tcgaggggct gcccccagga     2640

atcccgttcc gaaagccctg taccttcggc tcccagaacc tggagaggat tcttgctgtg     2700

gctgacaaga tcaagttcac agtcaccagg cctttccaag gactcatccc aaagcctgat     2760

gaagatgacg ccaacagact cggggagaag gtgatcctgc gggagcaggt gaaggaactc     2820

ttcaacgaga aatacggtga ggccctgggc ctgaaccggc cggtgctggt cccttataaa     2880

ctaatccggg acagcccaga cgccgtggag gtcacgggtc tgcctgatga catccccttc     2940

cggaacccca acacgtacga catccaccgg ctggagaaga tcctgaaggc ccgagagcat     3000

gtccgcatgg tcatcattaa ccagctccaa ccctttgcag aaatctgcaa tgatgccaag     3060

gtgccagcca aagacagcag cattcccaag cgcaagagaa agcgggtctc ggaaggaaat     3120

tccgtctcct cttcctcctc gtcttcctct tcctcgtcct ctaacccgga ttcagtggca     3180

tcggccaacc agatctcact cgtgcaatgg ccaatgtaca tggtggacta tgccggcctg     3240

aacgtgcagc tcccgggacc tcttaattac tagacctcag tactgaatca ggacctcact     3300

cagaaagact aaaggaaatg taatttatgt acaaaatgta tattcggata tgtatcgatg     3360

ccttttagtt tttccaatga tttttacact atattcctgc caccaaggcc tttttaaata     3420

agtaaaaaaa gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a              3471


<210>  1276
<211>  3426
<212>  DNA
<213>  homo sapiens

<400>  1276
taaatggcag ccaatggagg gtggtgttgc gcggggctgg gattagggcc ggggcgaatg       60

gctggcaatc ttactgggat tacagaacaa agagcctccc cgcgctcccg ctctccgctc      120

ctctccccgc gccgccccgc cctccgccgc agcccgcgcc gggggtgggg gccgccgagc      180

gccagccccc cggccggccg attccccccc cgcgccccct ccccgcgcct ccctccccgc      240

cctcgccgcg ccgccgtcct cgcctccctc tgcctctcct tcccccattc tcccggatta      300

attaaggagg cagcggcagg aggctgagtc ctggccgcgg gccggggccg gggcgccgct      360

ggcaggagcg cttggggatc ctccaaggcg accatggcct tgctgggtaa gcgctgtgac      420

gtccccacca acggctgcgg acccgaccgc tggaactccg cgttcacccg caaagacgag      480

atcatcacca gcctcgtgtc tgccttagac tccatgtgct cagcgctgtc caaactgaac      540

gccgaggtgg cctgtgtcgc cgtgcacgat gagagcgcct ttgtggtggg cacagagaag      600

gggagaatgt tcctgaatgc ccggaaggag ctacagtcag acttcctcag gttctgccga      660

gggcccccgt ggaaggatcc ggaggcagag caccccaaga aggtgcagcg gggcgagggt      720

ggaggccgta gcctccctcg gtcctccctg gaacatggct cagatgtgta ccttctgcgg      780

aagatggtag aggaggtgtt tgatgttctt tatagcgagg ccctgggaag ggccagtgtg      840

gtgccactgc cctatgagag gctgctcagg gagccagggc tgctggccgt gcaggggctg      900

cccgaaggcc tggccttccg aaggccagcc gagtatgacc ccaaggccct catggccatc      960

ctggaacaca gccaccgcat ccgcttcaag ctcaagaggc cacttgagga tggcgggcgg     1020

gactcgaagg ccctggtgga gctgaacggt gtctccctga ttcccaaggg gtcacgggac     1080

tgtggcctgc atggccaggc ccccaaggtg ccaccccagg acctgccccc aaccgccacc     1140

tcctcctcca tggccagctt cctgtacagc acggcgctcc ccaaccacgc catccgagag     1200

ctcaagcagg aagcaccttc ctgccccctt gcccccagcg acctgggcct gagtcggccc     1260

atgccagagc ccaaggccac cggtgcccaa gacttctccg actgttgtgg acagaagccc     1320

actgggcctg gtgggcctct catccagaac gtccatgcct ccaagcgcat tctcttctcc     1380

atcgtccatg acaagtcaga gaagtgggac gccttcataa aggaaaccga ggacatcaac     1440

acgctccggg agtgtgtgca gatcctgttt aacagcagat atgcggaagc cctgggcctg     1500

gaccacatgg tccccgtgcc ctaccggaag attgcctgtg acccggaggc tgtggagatc     1560

gtgggcatcc cggacaagat ccccttcaag cgcccctgca cttatggagt ccccaagctg     1620

aagcggatcc tggaggagcg ccatagtatc cacttcatca ttaagaggat gtttgatgag     1680

cgaattttca cagggaacaa gtttaccaaa gacaccacga agctggagcc agccagcccg     1740

ccagaggaca cctctgcaga ggtctctagg gccaccgtcc ttgaccttgc tgggaatgct     1800

cggtcagaca agggcagcat gtctgaagac tgtgggccag gaacctccgg ggagctgggc     1860

gggctgaggc cgatcaaaat tgagccagag gatctggaca tcattcaggt caccgtccca     1920

gacccctcgc caacctctga ggaaatgaca gactcgatgc ctgggcacct gccatcggag     1980

gattctggtt atgggatgga gatgctgaca gacaaaggtc tgagtgagga cgcgcggccc     2040

gaggagaggc ccgtggagga cagccacggt gacgtgatcc ggcccctgcg gaagcaggtg     2100

gagctgctct tcaacacacg atacgccaag gccattggca tctcggagcc cgtcaaggtg     2160

ccgtactcca agtttctgat gcacccggag gagctgtttg tggtgggact gcctgaaggc     2220

atctccctcc gcaggcccaa ctgcttcggg atcgccaagc tccggaagat tctggaggcc     2280

agcaacagca tccagtttgt catcaagagg cccgagctgc tcactgaggg agtcaaagag     2340

cccatcatgg atagtcaaga gagggattcc ggggaccctc tggtggacga gagcctgaag     2400

agacagggct ttcaagaaaa ttatgacgcg aggctctcac ggatcgacat cgccaacaca     2460

ctaagggagc aggtccagga ccttttcaat aagaaatacg gggaagcctt gggcatcaag     2520

tacccggtcc aggtccccta caagcggatc aagagtaacc ccggctccgt gatcatcgag     2580

gggctgcccc caggaatccc gttccgaaag ccctgtacct tcggctccca gaacctggag     2640

aggattcttg ctgtggctga caagatcaag ttcacagtca ccaggccttt ccaaggactc     2700

atcccaaagc ctgatgaaga tgacgccaac agactcgggg agaaggtgat cctgcgggag     2760

caggtgaagg aactcttcaa cgagaaatac ggtgaggccc tgggcctgaa ccggccggtg     2820

ctggtccctt ataaactaat ccgggacagc ccagacgccg tggaggtcac gggtctgcct     2880

gatgacatcc ccttccggaa ccccaacacg tacgacatcc accggctgga gaagatcctg     2940

aaggcccgag agcatgtccg catggtcatc attaaccagc tccaaccctt tgcagaaatc     3000

tgcaatgatg ccaaggtgcc agccaaagac agcagcattc ccaagcgcaa gagaaagcgg     3060

gtctcggaag gaaattccgt ctcctcttcc tcctcgtctt cctcttcctc gtcctctaac     3120

ccggattcag tggcatcggc caaccagatc tcactcgtgc aatggccaat gtacatggtg     3180

gactatgccg gcctgaacgt gcagctcccg ggacctctta attactagac ctcagtactg     3240

aatcaggacc tcactcagaa agactaaagg aaatgtaatt tatgtacaaa atgtatattc     3300

ggatatgtat cgatgccttt tagtttttcc aatgattttt acactatatt cctgccacca     3360

aggccttttt aaataagtaa aaaaagaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaa                                                                3426


<210>  1277
<211>  5220
<212>  DNA
<213>  homo sapiens

<400>  1277
gagggaaggc gcgcagacgc gcagcggccg gcctgctccg ggcgcgtcag gcagggggtg       60

gggagcaggg gccgggcggg cgctcggctc ccagccgcgc tccctcgggc cactagcgct      120

cccgcgcgcg cccggccgcc ttcatgtgaa gcgccggccc tccgcccctt ccctcccctt      180

ccttccctcc ctccctccct gtcccctcct cctcctcctc ctcctccggc gcccgcttca      240

gctccccggg gccccctgcc cggccgggcg ctgacagcaa gggcgggggt ccctgccgcc      300

gccttgtctc gcgcagggtc cggctggggt agcggagccc ccagtgcggc catggaccgg      360

cccctgtcgt cgtcggcgga ggcggaggag gaactggagt ggcaagtggc gagtcgcagg      420

aggaaggcct gggccaagtg ccgcagctcc tggcaagcgt cggagacgga ggatctgtcc      480

acagaagcga cgacgcagga cgaggaggag gacgaggagg aggacctccc cggcgcgcag      540

ctgccggcag cggggggaag aggaaacgtg cccaacgaga agatcgcgat atggctcaag      600

gactgccgta cacctttggg agcctcactg gatgaacaaa gcagtagtac actcaagggt      660

gtgcttgtga gaaatggagg aagttttgaa gatgatttgt cattgggagc tgaagccaac      720

cacctccatg aaagtgatgc tcaaattgaa aactgcaata atatcttggc caaagagaga      780

agattacagt ttcatcagaa agggagaagt atgaattcca ctggatctgg gaaaagtagt      840

gggacagttt caagtgtttc agaattgttg gaactttatg aggaagatcc tgaagaaatt      900

ctttataatc ttggatttgg acgtgatgaa ccagatattg cttctaaaat tccttccaga      960

ttttttaatt catcatcctt tgccaaaggg atagatatta aagtattttt gagtgctcag     1020

atgcaacgga tggaagtaga aaacccaaat tatgctttaa caagccgttt tcgtcaaatt     1080

gaagtgctta ctactgtggc caatgcgttt tcttctttat attctcaagt ctccgggacg     1140

cccctgcaga gaattggaag tatgtcctca gtgacctcta acaaggagac agacccacct     1200

ccacctttaa ctcgaagtaa cactgcaaat cgtttaatga aaacactctc aaaactgaat     1260

ttatgtgttg ataaaacaga gaaaggagaa agtagtagtc cttctccatc agctgaaaaa     1320

ggaaagattc taaatgtttc agtgattgaa gaaagtggca ataaaaacga tcaaaagtct     1380

caaaaaatta tgaagaagaa agagtcatct tctatgttgg ctacagttaa agaagaagtc     1440

tctggtagtt cagcagctgt tacggagaat gctgatagtg atagaatttc tgatgaagca     1500

aatagtaatt ttaaccaagg aactgaaaat gaacaaagta aagaaactca aagtcatgag     1560

agtaaactgg gtgaggaatc tggtattgta gaatccaaat tagatagtga tttcaacata     1620

tccagccaca gtgagctgga aaatagcagt gagctgaaaa gtgtccatat atccacacct     1680

gaaaaagagc cttgtgcacc actgacaata ccatccataa gaaatataat gacacagcag     1740

aaggactcct tcgaaatgga agaggttcaa agtacggagg gagaagctcc tcatgttcca     1800

gccacttacc agctaggtct tacgaagtcg aaaagagatc atctgttacg tactgcaagt     1860

cagcattccg atagcagtgg ttttgctgaa gattctacag actgcctatc ccttaatcat     1920

cttcaggttc aggagtcctt gcaggctatg gggagtagtg ctgatagttg tgacagtgag     1980

acaacagtta cgtcacttgg tgaagacctt gccacaccaa cagcacaaga ccagccttat     2040

tttaatgaat cagaggagga gtctcttgtc cctcttcaga agggactaga gaaggcagca     2100

gcagttgcag acaaaagaaa atcaggtagc caggatttcc ctcagtgcaa caccattgag     2160

aatacaggaa ctaaacagtc cacctgtagt ccaggggatc atatcattga aattactgaa     2220

gtggaagagg atttgtttcc agcagagaca gtagagctac tgagggaagc aagtgctgaa     2280

agtgatgtgg gtaaaagcag tgaaagtgaa tttactcagt ataccacaca ccatattctg     2340

aaatcattgg cttctattga agctaaatgc agtgatatga gctctgaaaa tacaactggg     2400

cctccctctt ccatggacag agttaataca gctttgcaaa gagctcaaat gaaggtttgc     2460

agtctgtcta atcaaaggat ggggcgtagc ctgctaaaat caaaagattt gttaaaacaa     2520

aggtacttat ttgcaaaagc tggctatcct ctaagaaggt ctcagtcttt accaaccacc     2580

ttattgagcc cagtaagggt tgtgtcctct gtcaatgttc gattatctcc aggaaaagag     2640

accagatgca gcccaccttc cttcacctat aagtacacac ctgaagagga gcaggaattg     2700

gaaaagcggg tgatggaaca tgatggtcag tctttagtta aatcgaccat tttcatctct     2760

ccatcatctg tgaagaaaga agaagccccc cagagtgagg cgccgcgggt ggaggaatgc     2820

catcatggaa ggactcctac ctgttcacgg cttgctccac caccaatgtc tcagtctacc     2880

tgttcccttc attccatcca ctctgagtgg caagaaaggc ccctgtgtga gcacacaaga     2940

actctgagca ctcacagtgt tcccaacata tcaggggcta cttgtagtgc cttcgcttcc     3000

cctttcgggt gtccttactc acatagacat gccacctacc cttaccgagt gtgctctgtg     3060

aatcctcctt cagccataga aatgcagttg cgaagagtat tacatgatat tagaaactca     3120

ctgcagaatc tttcacagta ccctatgatg agaggacctg atcctgctgc tgctccatat     3180

agtactcaga aatcatctgt tctacctctt tatgaaaata cttttcagga gctccaggta     3240

atgaggcgga gcctgaattt gtttagaaca caaatgatgg atttagaatt ggcaatgctg     3300

cgtcagcaaa ccatggttta tcatcatatg actgaggagg agaggtttga agttgatcag     3360

ctccagggtt tgagaaattc agtccgaatg gaacttcagg acctggaact gcagctggag     3420

gagcgcctgc tgggcctgga ggagcagctt cgtgctgtgc gcatgccttc acccttccgc     3480

tcctccgcac tcatgggaat gtgtggcagt agaagcgctg ataacttgtc atgcccttct     3540

ccattgaatg taatggaacc agtcactgaa ctgatgcagg agcagtcata cctgaagtct     3600

gaattgggcc tgggacttgg agaaatggga tttgaaattc ctcctggaga aagctcagaa     3660

tctgtttttt cccaagcaac atcagaatca tcttctgtat gttctggtcc ctctcatgct     3720

aacagaagaa ctggagtacc ttctactgcc tcagtgggca aatccaaaac cccattagtg     3780

gcaaggaaga aagtgttccg agcatcggtg gctctaacgc caacagctcc ttctagaaca     3840

ggctctgtgc agacacctcc agatttggaa agttctgagg aagttgatgc agctgaagga     3900

gccccagaag ttgtaggacc taaatctgaa gtggaagaag ggcatggaaa actcccatca     3960

atgccagctg ctgaggaaat gcataaaaat gtggagcaag atgagttgca gcaagtcata     4020

cgggaggttg gcatggatcc tattagctgt gtaatactgg aattatcaat gatatgcact     4080

ggtggaggtg ttatttgtgc tttagaagat acttgctgtt gagctgggct actgtataca     4140

gtgtacaatg tgtatttctt caaccatata ttttaaaaag acgtacatag aaacttaggc     4200

actttgctat ttcttttcta aactatcaaa aactctagca gtttgaaaag cctaatattt     4260

atttgtatgt cagtattttt catttgattc cctattagaa ttaattttaa aacttgaaga     4320

cttccagact tatccaactt ataaataaca tatttcttca gactaacatc ttaaaacact     4380

gacctctatg aggtatttac tgtgcaataa ctgattcatt tttttcagag cttgaagcat     4440

ccaatgattt ttccctccac tgctgttaat taatgtcact tccaagaaga aaaactgttc     4500

tgttgtaaaa aatataattg ctcttaattc ttggggaggt tactaatagc agtaggatag     4560

aattttatga ggttacctac aactacttaa tgtacttaca ctgtaagcct tgttgcttta     4620

cccaagacaa atgtaatttt atcattgctt atgtagtatt tttcttttgg aaatgtgcct     4680

tatgttaaac actatgtact tttacttttt gcattgtcca gacttcttta ttagatggag     4740

atgtttcttt ttctgtcttc tagactaaat agagtatcat ccaaataatg gggcctatga     4800

cttgaatgaa tagaaatgaa taagctggtg tttgtttttt caaaatggaa gtaatttaga     4860

tttgttctcc tcatacataa aatgatttta gttcagtttt aaccagtgaa aactttgttt     4920

ttatgaaaaa aaaggaaaat ggtttcccat ttggttttat atgtgttaaa taaatgtgta     4980

aagtaaccac caaatgttat tagaattttt cttctagcat ttataatttt ttcaactcct     5040

attgtgtttc tttgtgtgtg atattttaat caaaagtggt tgagttgtta acagtgttct     5100

ttgaaagaat ctctaaaagg cttataaatg tttgaaatat cacacaaagg ctgatttcta     5160

aaatatatat atattaaaac aataaagtat ttattttgcc taaaaaaaaa aaaaaaaaaa     5220


<210>  1278
<211>  13804
<212>  DNA
<213>  homo sapiens

<400>  1278
ggtgctcgcg aaagctcgct gtcgctggga ggcgcgcgcc ggcgttcctc ggccgctccg       60

ggtacctgag ggacgcgcgg ccgcccgcgg caggcggtgc agccccccca ccccttggag      120

ccaggcgccg gggtctgagg atagcatttc tcaagacctg acttatggag cacttgtaac      180

ctgagatatt tcagttgaag gaagaaatag ctcttctcct aagatggaat ctgtggtttg      240

ggaatgtggt tgatcaactt gatatgttgg ccaaatgtgc cccatgtaat aaaatgaaaa      300

gaagagacaa gatgatgtca ttttcccata ttgtgaaacc aaaaacaaac gccttttgtg      360

agaccaagct aacaaacctc tgacggtgcg aagagtattt aactgtttga agaatttaac      420

agtaagatac agaagaagta ccttcgagct gagacctgca ggtgtataaa tatctaaaat      480

acatattgaa taggcctgat catctgaatc tccttcagac ccaggaagga tggctatgac      540

ttggattgtc ttctctcttt ggcccttgac tgtgttcatg gggcatatag gtgggcacag      600

tttgttttct tgtgaaccta ttaccttgag gatgtgccaa gatttgcctt ataatactac      660

cttcatgcct aatcttctga atcattatga ccaacagaca gcagctttgg caatggagcc      720

attccaccct atggtgaatc tggattgttc tcgggatttc cggccttttc tttgtgcact      780

ctacgctcct atttgtatgg aatatggacg tgtcacactt ccctgtcgta ggctgtgtca      840

gcgggcttac agtgagtgtt cgaagctcat ggagatgttt ggtgttcctt ggcctgaaga      900

tatggaatgc agtaggttcc cagattgtga tgagccatat cctcgacttg tggatctgaa      960

tttagctgga gaaccaactg aaggagcccc agtggcagtg cagagagact atggtttttg     1020

gtgtccccga gagttaaaaa ttgatcctga tctgggttat tcttttctgc atgtgcgtga     1080

ttgttcacct ccttgtccaa atatgtactt cagaagagaa gaactgtcat ttgctcgcta     1140

tttcatagga ttgatttcaa tcatttgcct ctcggccaca ttgtttactt ttttaacttt     1200

tttgattgat gtcacaagat tccgttatcc tgaaaggcct attatatttt atgcagtctg     1260

ctacatgatg gtatccttaa ttttcttcat tggatttttg cttgaagatc gagtagcctg     1320

caatgcatcc atccctgcac aatataaggc ttccacagtg acacaaggat ctcataataa     1380

agcctgtacc atgcttttta tgatactcta tttttttact atggctggca gtgtatggtg     1440

ggtaattctt accatcacat ggtttttagc agctgtgcca aagtggggta gtgaagctat     1500

tgagaagaaa gcattgctgt ttcacgccag tgcatggggc atccccggaa ctctaaccat     1560

catcctttta gcgatgaata aaattgaagg tgacaatatt agtggcgtgt gttttgttgg     1620

cctctacgat gttgatgcat tgagatattt tgttcttgct cccctctgcc tgtatgtggt     1680

agttggggtt tctctcctct tagctggcat tatatcccta aacagagttc gaattgagat     1740

tccattagaa aaggagaacc aagataaatt agtgaagttt atgatccgga tcggtgtttt     1800

cagcattctt tatctcgtac cactcttggt tgtaattgga tgctactttt atgagcaagc     1860

ttaccggggc atctgggaaa caacgtggat acaagaacgc tgcagagaat atcacattcc     1920

atgtccatat caggttactc aaatgagtcg tccagacttg attctctttc tgatgaaata     1980

cctgatggct ctcatagttg gcattccctc tgtattttgg gttggaagca aaaagacatg     2040

ctttgaatgg gccagttttt ttcatggtcg taggaaaaaa gagatagtga atgagagccg     2100

acaggtactc caggaacctg attttgctca gtctctcctg agggatccaa atactcctat     2160

cataagaaag tcaaggggaa cttccactca aggaacatcc acccatgctt cttcaactca     2220

gctggctatg gtggatgatc aaagaagcaa agcaggaagc atccacagca aagtgagcag     2280

ctaccacggc agcctccaca gatcacgtga tggcaggtac acgccctgca gttacagagg     2340

aatggaggag agactacctc atggcagcat gtcacgacta acagatcact ccaggcatag     2400

tagttctcat cggctcaatg aacagtcacg acatagcagc atcagagatc tcagtaataa     2460

tcccatgact catatcacac atggcaccag catgaatcgg gttattgaag aagatggaac     2520

cagtgcttaa tttgtcttgt ctaaggtgga aatcttgtgc tgtttaaaaa gcagatttta     2580

ttctttgcct tttgcatgac tgatagctgt aactcacagt taacatgctt tcagtcaagt     2640

acagattgtg tccactggaa aggtaaatga ttgctttttt atattgcatc aaacttggaa     2700

catcaaggca tccaaaacac taagaattct atcatcacaa aaataattcg tctttctagg     2760

ttatgaagag ataattattt gtctggtaag catttttata aacccactca ttttatattt     2820

agaaaaatcc taaatgtgtg gtgactgctt tgtagtgaac tttcatatac tataaactag     2880

ttgtgagata acattctggt agctcagtta ataaaacaat ttcagaatta aagaaatttt     2940

ctatgcaagg tttacttctc agatgaacag taggactttg tagttttatt tccactaagt     3000

gaaaaaagaa ctgtgttttt aaactgtagg agaatttaat aaatcagcaa gggtatttta     3060

gctaatagaa taaaagtgca acagaagaat ttgattagtc tatgaaaggt tctcttaaaa     3120

ttctatcgaa ataatcttca tgcagagata ttcagggttt ggattagcag tggaataaag     3180

agatgggcat tgtttcccct ataattgtgc tgtttttata acttttgtaa atattacttt     3240

ttctggctgt gtttttataa cttatccata tgcatgatgg aaaaatttta atttgtagcc     3300

atcttttccc atgtaatagt attgattcat agagaactta atgttcaaaa tttgctttgt     3360

ggaggcatgt aataagataa acatcataca ttataaggta accacaatta caaaatggca     3420

aaacattttc tctgtattca ttgttgtatt tttctacagt gagatgtgat cttgccaaag     3480

ccaccagacc ttggcttcca ggccctcctg tagtgagttg attgtctgca cttgccttgc     3540

ccaatagcca gtaggctaca gcttttgccc cacaccctta ttttcagatt ctggatcatt     3600

cttgtttaca actgaaatat atataacctc agtccaaagt ggtgattgat ttgagtattt     3660

gaaaattgtt gtagctaaat gaagcatgat tagtcttagt atgaatatca tttaatcttt     3720

aaaaaatcaa gtaaaaatgt ttatctgata atgtttaaat aatttacaat ataaactgta     3780

aaacttatta ggcatgaaat caatcagaag agaaagaaaa atgctggaac atgcttgatg     3840

tattatgtaa aaagcatatt taaacaaggg tcctcaaccc tgactgcaga taagaatcac     3900

ttgggttact tcagatgcct aacaccttcc tctcatacaa ataagaattg gtagctttct     3960

taaaaaaaaa aaaaaaaaaa aaaagcgctc caggtgattc taatctgcag cctggcttga     4020

aactcactac tttaacttgc ccctgatgat ctgtcggcat catatatcac atgaacatcc     4080

acatggattc tgtctttcgc ttttatatca ttatctaata ttcagttgtt ctgcacctga     4140

tgccaaattc tgggctgtac tcctagagag acttactcag taaggccaaa gtgataggac     4200

tttaaaatct gtagttataa aaataccgca ggtgattctt acggaggtaa tccaagaatc     4260

atactttgaa gaattattct agactctgaa gaggcctggc tctgccttat gctattatag     4320

tttatgacct ttaacaattt aactctccga gcctcagttc ccttgtttgt aaatgaagat     4380

agaagataaa tacgtactct acctacctca caaagctgtc agattaagat caagtgaaaa     4440

aaattatgtg aaagctcttt gaaaactgta aagcattatg aatgataagg gattaggtta     4500

ttgtggattt aagaggtgtg aggactgcta tagtacattc cttgacgtgt gttgaattca     4560

tgtatacttt ctttcttacc ctttaaaaca aactgccaag aaattaggtg ttgaaaaaga     4620

atattctcat caggcagcaa agtcagtttt ctgatagtaa taatttgtct attatgttat     4680

atatttcaaa gtacatgtat gataatatga cttattcttc atgagagata tttgaatatt     4740

tggcccaaaa tgtttttcat ttttctctgt gttcattgcc tttctccttg gagctggagt     4800

taatgctcaa agcaggcagg tctgaattcc ctcataaccg acaattagta aacattttct     4860

ctgaaagcca aacatataac aacttattta tcaataattc atgaagcttt tgtctgagaa     4920

tctctcctgc aaacagcatg agagaactaa aacaaacatt cacaaacaaa aataagttaa     4980

aatagaaggt accagtttgg gctcgaagat gttgtcatcc attgccatct gcattatatt     5040

atcaactgcc aaaatgttaa ttggttttct tttacaagtg ggccaagtat agacagttaa     5100

gtgaacatca ctatgaaaat cttaactttg tgcttctaga tttttagata atcatttgta     5160

ttttctctat taaattgtgg gtatgtatgg gaatactata ttgacttttc agttactttc     5220

agtaagtatc ttaattttgt cccacaaaat ttatgtaata ttaatccatg gttttaaaca     5280

acagtattca gtttgggcag cagttttaag tctaactagc ttaaaccaat ctgaataagt     5340

ctggacagtt ttcctaccat atgtttaact ttgattggca tatgataatg tttagtgttt     5400

tcttttttca gttgacaact gagaaaataa tagttctctc taacatgtta atatattatc     5460

aaaaggtttt caaaaagtac tttgatttca gcaacttttt ttattcaata actagacaaa     5520

agatctaaga taatattaaa ctcaaaacag tttgtttcaa agaacaattg gttaataact     5580

cagctggcac agggattcat acacagtttt tcaataaata tttaaatgaa caattcatgt     5640

cacacaactt gcttttaccc tagtactgag tctcacatca aagaaatttg aaagatctat     5700

aacctatgtg aaatgaagtc tctgctttac cagaataata tgtggcaggt aataaatatg     5760

taaagtacac caaatgaaac atattttgca tagataacag tccatatcac tattataatt     5820

aaagaaatat atgtacagac atgtaccaat ccttttaatt aattttagaa gatgaacagt     5880

gattcttaga agtgagtaat tagactcctt ttagtcttat gctgttagat ctttgtggac     5940

cagctgagta aatgaatctt caaatcaacc tttctttttc tgctgctctt agagcagatt     6000

tataaaaatc ctaagaatgt cttcaaatta gaaaaattta ctacatttta acctacctca     6060

tcagtttctt tgtgataata gctgaaaata actcaaactg tacccatctt agttaggcta     6120

tatctctgtg aaatgaaagg aaccacttaa ttttttttat ataaattagt gaatcatttg     6180

ctggagctta gaaaatatta acataccaaa atttcattat gatgatattt atattgcttt     6240

ttgacatgcc aaaggtacat ttacatatta ccatatttgg atgacttaca tagtctggtg     6300

taatgaaaat tcccctggga ttggaatttt aagactcatg atgtcaactg ggctggtcat     6360

tttatttctc tgagtctttg tttcttcaat gtaaaatgtg gataaggtaa tttttggttt     6420

tagcctccct cactggatat tgtaaggatc aaatgaaata gtatttatta taatgctctg     6480

taacccataa attattctac ttaaaaaaat tttttataga gacagggtct tgctctgtca     6540

cacaggctgg agagcagtgg cataatcata gttcattata accttgaact cctaggctca     6600

agcagtcctc cagcttcagc ctcccaagta gctaagactg taggcatgca ccactacacc     6660

tggctaattt taattttttt ttcttttttt gagacggagt ctggctttgt tgcccaggct     6720

ggagtgcagt ggcacaatct cagctcactg caacctccac ctcccaggtt caagtgattc     6780

ttctgtctca gcctcccgag taactgggac tacaggtgcg tgccaccaca tccagctagt     6840

ttttgtattt ttagtggaga tggagttttg ccatgttggt ctcaaactcc tgacctcaag     6900

tgatctgccc acctcagcct cccaaagtgc taggattaca ggcatgagtc actgcacctg     6960

gcttaatttt aattttttta attttttgta gagatgagtc tcactatgtt gaccaggctg     7020

gtcttgaact cctggcctcc taaagcactg ggattacaag catgagccac catgcctgat     7080

ccataaattg ttctactgat accatttggt tttgttagaa tttggggggg ctatagaaaa     7140

caaggttaca gtcttcatta gtatttcttt ttagcaataa caacaaaata ggcaattaga     7200

ccagtgttca tttggtacag tctttaaatc ggtcatccaa ttaaccttta aaaagtaggt     7260

tatgctctta aattgtattg gttctttaat atgtgttata ccagagtatg cctcaaattt     7320

tatgtagttg aatttgtaga acaaatttgg ggatattcat tttatttttc cttttatatg     7380

aaattgtata agtacattag cttgacttaa attataaaaa aaaatatata tgaagaagaa     7440

tgtagaccct ataatgtttt ttgtctttga ctttttggct tttatgtacc tcattttttc     7500

tgattgagaa aaagttttga aaaagtgatt cacttgttgg ttttcattgt ggcaaaactt     7560

taaattttaa gtcatcacac tatgagaatt gtttgtacac atttataatt tttttaaagt     7620

atgtaaagta aggatttttt ctccattctt cactcacaaa ggatagcatt tttatggaac     7680

ctagatttac aaaggaactt gtgattcttt tcaatgcttt tgtgtcgttt tacagctgat     7740

taagaaaaaa tgtttacatt taattcagct gtatttccta gtagctgtat aatcttacac     7800

attattctta tataattttg acctatttta tatgaaaata attgtattgg catctcttca     7860

taatttaatt ctcttctctc cttcttttgt tccgattaga tgaatttggg aaaggagtag     7920

gaagactagg tatcgcatgc cttccgtctg attgtaatca gtctcctggg ttttttacta     7980

atttaatctt aatcctgtgc ttctttagtc atcaaattga tataggatta caattttctc     8040

tcaggatcca agtcttctaa gaatgaaaat gttgaagtct acccagaacc agccatcctt     8100

gtagacattt ctatttggtt gatttataaa gatttaatat ataaagattt aatatgagtt     8160

aaacatgttt cttattctgt gatctctaat tagaaagtaa aattctgttg ccataaatat     8220

aaaagaaagt tttcacttat attttagtca aacaccaaac cactgcatta cttacttcct     8280

ataagacaca gtagttcaat ctgttgaaag gcattgaagg ataatttcct tcagattact     8340

ttttaaatca tcatctgcct caggaaattc tttcttgaat ttttttgttg gtgtgaaagc     8400

gttgcttata ctttatgctc attttattgg tcactgtcac cagtttttcc cgataaagat     8460

taaaaatgtt ttttaccttg aaataattca gattttgaag attcactgtt tcattatttt     8520

gctaattacc attaactagt aaagttagtt tttaaagttt ttttaaggtt gatattttat     8580

catattcctg gagtaggatg gattacttta ttattattgt agctttaagg ttttttgttg     8640

tataagtcag cttgtttgta tatgctaaat tgcagatatt tctttgtgtt gtgcttattg     8700

gttttttttt ttaacttaga gcttaataat ttctattttc tatcctggag tctaaaatta     8760

aacaaaaaaa tctattttct aaattggcag gattttttta atgattagta aaactgtatt     8820

attttatttt taaaaataca ataggatttt gagtcaggaa acttgacttc tactcttgcc     8880

tctcttttgc agttagctgt gtaactttgg ataaggcatt ttatctcgtg gtgcctccat     8940

ttttctcatt ctctagggaa caagagaatt agtttaggta gcgtctaaaa ttccgcccag     9000

ctctcatttg gttctcattt gaccatttta taatcattat tttggtctca tttttattct     9060

tcttattcat cccatgaact agatcaactt gtattatttt actagatcaa cctgtattat     9120

taacgtcatt tacatgtaaa ttgatgggat tcagatattt tatcaactgt ttttccatta     9180

gtgattttaa gtaattttaa agaaggaaaa ttatattaca gataataaaa atgaaagaaa     9240

gttataaata ttggacatgg cttttttaaa tgggaaagtc ttcttaagca ccaatataag     9300

caccttaaat tgatacatag aaaagaatga cataacgttt tgtggtcttt gttctcttaa     9360

atatgaatat agctagttag cctaaaattt acacaaaatg tattcaagat caaattagtg     9420

aacaaagcaa tggttcgtat ggctaattta aaagcaattc aatttaccaa tattaaaata     9480

attataaaat gtaaaagaaa tttcagagga gttgattgaa aattttttgt tcagtaatta     9540

ttcttaaact gcattcttag gtttattaca taaatatagt tgccagattg ccatgggcaa     9600

gtgaatgtct tcatttgaaa tattattaga gatcaatgtg gcttgttatt tttaattttt     9660

ttctggctat acagaaaatg tttctggaaa aattccttaa ttgtcatctg atataatgta     9720

gagattgagg ccagacgcag tggctcacgc ctgtaatccc agcactttgg gaggccaagg     9780

tgggcagatc acctgaggtc aggagttcga gaccagcctg atgaacatgg caaatcccct     9840

tctgtactaa aaatacaaaa attagccagg cgcagtggct cacgcctgta atcccaacac     9900

tttgggaggc cgaggcgggc ggatcacgag gtcaggagat caagaccgtc ctggctaaca     9960

tggtgagacc ctgtctctac taaaaacaaa aaaattagtt gggcatggtg gcgggcacct    10020

gtagtcccag ccactcggga ggctgaggca ggagaatggc gtgaacccgg gaggcggagc    10080

ttgcagtgag ctgagatcgc accgctgcac tccagcctgg gcaacggagc gagactctat    10140

ctcaaaaaaa aaaaaagaaa aaaaaaaaag tagagattgc attagttcca tatctccgca    10200

gagttctctg gtagattaaa tgttctctgt gcactaggcc aaggaagttc ctgttacctt    10260

tgaaaatcat tgtgtttgct ctgattgtct acattagctc atatcagtct tttgaacact    10320

ggttcaaatc tgggtgttgg gttaggatct gatgagtaga gaatagtgga aagttgatat    10380

aggaaggtat actggtttct ggtgtgattc tttagctaca tttattcctt gtcttatgtc    10440

atttcactgg atcatgtaac tgtcctggct ttcagaaatt atattagatg cccagccttt    10500

ctcattcaga gatgcctgta ttattatgtt atttcgattg cctaccaaaa aaaaaaaaaa    10560

aagaaaaggt ttgtttttag ttctctgcct ctgcaagtct ttgtgatcac atttgttaaa    10620

ttgaatctga gattcaaata tttcatttaa tattttctgg gttttgataa tgggatattc    10680

tgtaagataa agcaagtaat cctagagtga tttactttat gtttagccat ccaccatttt    10740

cctatttctc tactcctccc attctccatt tttaaaagga aattaacaaa tgtcttcctt    10800

tatccctgcc tcagataatt tttccctgaa ctcatcttgt cagcagaaac atttaatgtg    10860

aaataattct gtatttctga gacaagatca acacagtagt tctttacatt gagctgaggt    10920

gaatgtatac ttaaaaatac tctattttct ttttatatga acttaaaatt tttaaaatca    10980

tatatgggac tccccaatgt gaaaatatta gtctggacat tctcttgcca tcaggtgcta    11040

tttctacctt agctgtgagt tagactaaat ccaaatttcg tatcattcat ctttttataa    11100

tatttaactt ccctagaatc accccatttc atgtctttaa ccccaacttc caacaacttt    11160

tctgctttta ttttcaaatg tcaaattgta tttttgtgtt ttattttctc attgaagtgt    11220

aaaagtatca catatatgaa ggaatggctg gtttagacat ttactttggc atagtaaaga    11280

ttgatattga taccacccac catcctttcc tctagcccca gaaagaaaag tttgacaact    11340

caaaaacgat taaattatct tatcttgtta tttaatagaa caatggaagc tgtttcgtca    11400

aaattaaaat actttaccaa aaaaatactt ttttgtattt taatctgata gtgaatttgg    11460

ggattattta tgtaaatgta tcataattaa tagtaattat gagttatttc actctctgta    11520

atttgtgata cccaagattc atatttattt aatgtgaggt gttttttgag gcttttttgt    11580

tttatcttgt tttcttaact ttttacagtg ttgttagatt atcgcggtca tctcggcatg    11640

tggatcgctc ctcctgtaga tcagctgttc tctcttagag tcaggacaag gaggtttttg    11700

ctacatggtc gtagttggat aatacagcat tattctgaac tatctgaaat tgctggtttt    11760

attggtcaaa aatgatcaga tgctagcaat ttcataatag atatattcaa gaaggaacca    11820

aactttaaaa gatcttttag aataggtatg ttaacttctc atcctaaccc tatcaatata    11880

tcagaggctt tatgaaggag actctacaga taaccacaaa tcttatcaag aaaattctcc    11940

ttaaaaaaag ttatccttta ttttgttgtt aaatttccca gtttttaaaa gtgttttatc    12000

aaaatgactt cataattgaa gcaaatacct tttggaagta tatatgttac ataagacttt    12060

cactaaatct gtgcgtaaag cttttataat ctgagatatt gttatgtatt aggtttgtgc    12120

aaacctaata taaaagggtt catctgtaag tatcatttag aggcaaaata atttccccct    12180

cacatctaat gtggactcaa attttggcaa ctggaatgtt atcctcttgg taggcattct    12240

aaattaatga atactgctat gtggtgtagt aaacaaattt gccataaaat gccatttaag    12300

gattttcttt ttacctttat ttcattataa aagtatatga gttgaagatc atataaaaaa    12360

tatgaaactc ctacacagga aatccccaat tttgtgattt aataggttgt aaaaagagtt    12420

gttccaaatt cagactacat ctcatcatat aaataatatt atgaataata agggtaaaag    12480

attagccaac aaaagctaat ctagtacacc ccatagaggt actccaggtg tcttggtttt    12540

ggataaattt ttatagtgga gaaaggttac tttgatctct caataattgc ttggtacact    12600

tcttcctagg caatatgctc atgataccct cttcatgtga cctattcctc aaatgctgca    12660

ttctccaaaa cttccttacc tgccttctat cccctagtca ttcttatcaa tacttccaaa    12720

atataaccta tctcaagtgt tagaaatttg ctttaactaa tttatattaa agtgttagtg    12780

actatagccc ttttatctct cttaaagaga aatctgcatt aaaagcaaac acattgctgt    12840

tagctcaaat taatgtcagt gagtagaatc ttaagcttta aaacaaaagt ggaaataatt    12900

taaattagtg ttgatgggac tattttgagg caagagatac cattaagtga cctagcttgg    12960

aaatctgccc cctttgccca aacccatgtg atgtctgaaa ctactgtata ttttcaatga    13020

ccttgagaaa gggagctagt catttgtatt tatgggcctt atgaagtcag ggcctgctga    13080

tcctgttttt taagttcaag cgcaatgcct gaagcatcct agatctcctt caccctcatt    13140

ctacctgaca gacagctagg tctgtcttcc agctctttct cattgatact acctttacat    13200

atgaatacta tccatgcttg ttaaaaaaaa aaaaagtctt tccccatttt actgttacaa    13260

tttttcaaga gctataaagg tagaaaaagt attccttttc attattctaa aaaatatgtc    13320

atttttaaat agctggcact tagcagttta gttttccaaa ctttattctg aatcaaattg    13380

ctgaggtgat tctaaatgtc taatgttgat ttatcatata aacatctaat tagaaagtgt    13440

ttatgctaaa gacttgtatt ttgtggcatt agttcttcat gtttcttttt tatatgttta    13500

ttaaaattgt tcacttccaa atgagtggaa aagttgctgt tgttgggatg tacagggcaa    13560

gtgcacttgg ttagagcatg aactgggaat ttcacattct ctgatgtgct ttgcactctg    13620

ctcttgtaga tttattttgt ttacagtaga ctgatgtcag tttttgtaaa tgttttttct    13680

tagcacttta actgtgagtg tacaaactga ttttaaatgt agtggttgta tattttggtt    13740

ataaattgga gatttttaat aaaattaaat aattctcttt tctgtcaaaa aaaaaaaaaa    13800

aaaa                                                                 13804


<210>  1279
<211>  4912
<212>  DNA
<213>  homo sapiens

<400>  1279
attggggtct gctctaagct gcagcaagag aaactgtgtg tgaggggaag aggcctgttt       60

cgctgtcggg tctctagttc ttgcacgctc tttaagagtc tgcactggag gaactcctgc      120

cattaccagc tcccttcttg cagaagggag ggggaaacat acatttattc atgccagtct      180

gttgcatgca ggctttttgg cttcctacct tgcaacaaaa taattgcacc aactccttag      240

tgccgattcc gcccacagag agtcctggag ccacagtctt ttttgctttg cattgtagga      300

gagggactaa gtgctagaga ctatgtcgct ttcctgagct accgagagcg ctcgtgaact      360

ggaatcaact gcttcaggga aaaagaaaaa aaaaaaaaaa agacttgcct gggaggccgc      420

gagaaacttg cattggaagc ttcagcaacc agcattcgag aaactcctct ctactttagc      480

acggtctcca gactcagccg agagacagca aactgcagcg cggtgagaga gcgagagaga      540

gggagagaga gactctccag cctgggaact ataactcctc tgcgagaggc ggagaactcc      600

ttccccaaat cttttgggga cttttctctc tttacccacc tccgcccctg cgaggagttg      660

aggggccagt tcggccgccg cgcgcgtctt cccgttcggc gtgtgcttgg cccggggaac      720

cgggagggcc cggcgatcgc gcggcggccg ccgcgagggt gtgagcgcgc gtgggcgccc      780

gccgagccga ggccatggtg cagcaaacca acaatgccga gaacacggaa gcgctgctgg      840

ccggcgagag ctcggactcg ggcgccggcc tcgagctggg aatcgcctcc tcccccacgc      900

ccggctccac cgcctccacg ggcggcaagg ccgacgaccc gagctggtgc aagaccccga      960

gtgggcacat caagcgaccc atgaacgcct tcatggtgtg gtcgcagatc gagcggcgca     1020

agatcatgga gcagtcgccc gacatgcaca acgccgagat ctccaagcgg ctgggcaaac     1080

gctggaagct gctcaaagac agcgacaaga tccctttcat tcgagaggcg gagcggctgc     1140

gcctcaagca catggctgac taccccgact acaagtaccg gcccaggaag aaggtgaagt     1200

ccggcaacgc caactccagc tcctcggccg ccgcctcctc caagccgggg gagaagggag     1260

acaaggtcgg tggcagtggc gggggcggcc atgggggcgg cggcggcggc gggagcagca     1320

acgcgggggg aggaggcggc ggtgcgagtg gcggcggcgc caactccaaa ccggcgcaga     1380

aaaagagctg cggctccaaa gtggcgggcg gcgcgggcgg tggggttagc aaaccgcacg     1440

ccaagctcat cctggcaggc ggcggcggcg gcgggaaagc agcggctgcc gccgccgcct     1500

ccttcgccgc cgaacaggcg ggggccgccg ccctgctgcc cctgggcgcc gccgccgacc     1560

accactcgct gtacaaggcg cggactccca gcgcctcggc ctccgcctcc tcggcagcct     1620

cggcctccgc agcgctcgcg gccccgggca agcacctggc ggagaagaag gtgaagcgcg     1680

tctacctgtt cggcggcctg ggcacgtcgt cgtcgcccgt gggcggcgtg ggcgcgggag     1740

ccgaccccag cgaccccctg ggcctgtacg aggaggaggg cgcgggctgc tcgcccgacg     1800

cgcccagcct gagcggccgc agcagcgccg cctcgtcccc cgccgccggc cgctcgcccg     1860

ccgaccaccg cggctacgcc agcctgcgcg ccgcctcgcc cgccccgtcc agcgcgccct     1920

cgcacgcgtc ctcctcggcc tcgtcccact cctcctcttc ctcctcctcg ggctcctcgt     1980

cctccgacga cgagttcgaa gacgacctgc tcgacctgaa ccccagctca aactttgaga     2040

gcatgtccct gggcagcttc agttcgtcgt cggcgctcga ccgggacctg gattttaact     2100

tcgagcccgg ctccggctcg cacttcgagt tcccggacta ctgcacgccc gaggtgagcg     2160

agatgatctc gggagactgg ctcgagtcca gcatctccaa cctggttttc acctactgaa     2220

gggcgcgcag gcagggagaa gggccggggg gggtaggaga ggagaaaaaa aaagtgaaaa     2280

aaagaaacga aaaggacaga cgaagagttt aaagagaaaa gggaaaaaag aaagaaaaag     2340

taagcagggc tggcttcgcc cgcgttctcg tcgtcggatc aaggagcgcg gcggcgtttt     2400

ggacccgcgc tcccatcccc caccttcccg ggccggggac ccactctgcc cagccggagg     2460

gacgcggagg aggaagaggg tagacagggg cgacctgtga ttgttgttat tgatgttgtt     2520

gttgatggca aaaaaaaaaa agcgacttcg agtttgctcc cctttgcttg aagagacccc     2580

ctcccccttc caacgagctt ccggacttgt ctgcaccccc agcaagaagg cgagttagtt     2640

ttctagagac ttgaaggagt ctcccccttc ctgcatcacc accttggttt tgttttattt     2700

tgcttcttgg tcaagaaagg aggggagaac ccagcgcacc cctccccccc tttttttaaa     2760

cgcgtgatga agacagaagg ctccggggtg acgaatttgg ccgatggcag atgttttggg     2820

ggaacgccgg gactgagaga ctccacgcag gcgaattccc gtttggggct tttttttcct     2880

ccctcttttc cccttgcccc ctctgcagcc ggaggaggag atgttgaggg gaggaggcca     2940

gccagtgtga ccggcgctag gaaatgaccc gagaaccccg ttggaagcgc agcagcggga     3000

gctaggggcg ggggcggagg aggacacgaa ctggaagggg gttcacggtc aaactgaaat     3060

ggatttgcac gttggggagc tggcggcggc ggctgctggg cctccgcctt cttttctacg     3120

tgaaatcagt gaggtgagac ttcccagacc ccggaggcgt ggaggagagg agactgtttg     3180

atgtggtaca ggggcagtca gtggagggcg agtggtttcg gaaaaaaaaa aagaaaaaaa     3240

gaaaaaaaaa gaaaaaaaaa agattttttt cttctcttaa tcggaatcgt gatggtgttg     3300

gattatttca atggtggggt taatatagca tgttatcctg tctatctttt aaagatttct     3360

gtataagact gttgagcagt ttttaaaata gtgtaggata atataaaaag cagatagatg     3420

gcgctatgtt tgattcctac aacgaaatta tcaccagctt tttttcattc ttaactcttt     3480

aaaggattca aacgcaactc aaatctgtgc tggactttaa aaaaacaatt caggaccaaa     3540

ttttttctca gtgtgtgtgt ttattcctta taggtgtaaa tgagaagacg tgtttttttc     3600

cttcaccgat gctccatcct cgtatttctt tttccttgta aatgtaatca gatgccattt     3660

tatatgtgga cgtatttata ctggccaaac atattttttc ttttgtccct ttttttcttt     3720

cctttctttt tacttccttt atttctttat tccttccttt tccttttttt cttttttttt     3780

tctttttttt tttttttttt tggtagttgt tgttacccac gccattttac gtctccttca     3840

ctgaagggct agagttttaa cttttaattt tttatattta aatgtagact tttgacactt     3900

ttaaaaaaca aaaaaagaca agagagatga aaacgtttga ttattttctc agtgtatttt     3960

tgtaaaaaat atataaaggg ggtgttaatc ggtgtaaatc gctgtttgga tttcctgatt     4020

ttataacagg gcggctggtt aatatctcac acagtttaaa aaatcagccc ctaatttctc     4080

catgtttaca cttcaatctg caggcttctt aaagtgacag tatcccttaa cctgccacca     4140

gtgtccaccc tccggccccc gtcttgtaaa aaggggagga gaattagcca aacactgtaa     4200

gcttttaaga aaaacaaagt tttaaacgaa atactgctct gtccagaggc tttaaaactg     4260

gtgcaattac agcaaaaagg gattctgtag ctttaacttg taaaccacat cttttttgca     4320

ctttttttat aagcaaaaac gtgccgttta aaccactgga tctatctaaa tgccgatttg     4380

agttcgcgac actatgtact gcgtttttca ttcttgtatt tgactattta atcctttcta     4440

cttgtcgcta aatataattg ttttagtctt atggcatgat gatagcatat gtgttcaggt     4500

ttatagctgt tgtgtttaaa aattgaaaaa agtggaaaac atctttgtac atttaagtct     4560

gtattataat aagcaaaaag attgtgtgta tgtatgttta atataacatg acaggcacta     4620

ggacgtctgc ctttttaagg cagttccgtt aagggttttt gtttttaaac ttttttttgc     4680

catccatcct gtgcaatatg ccgtgtagaa tatttgtctt aaaattcaag gccacaaaaa     4740

caatgtttgg gggaaaaaaa agaaaaaatc atgccagcta atcatgtcaa gttcactgcc     4800

tgtcagattg ttgatatata ccttctgtaa ataacttttt ttgagaagga aataaaatca     4860

gctggaactg aaccctaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa             4912


<210>  1280
<211>  4850
<212>  DNA
<213>  homo sapiens

<400>  1280
agtgcggagc cttaggcgga gcgaagagaa ccggtcgcgg caatcctagc gcgcagcagc       60

agcagcagca gcagcagcag cagcagcagc agcagcagca cccgcatccg ctgcgggagt      120

ccgagccgga accacaccca agtagctgcc ctttcctctt ctgtcatctc accgccccac      180

cacagaccgc gttccccgag gaaaccggcc gcccacgccc ggagcatcct cccctgttga      240

gcgggcgctg acggacccgg cggcatgatg cggctgcgag gctcggggat gctgcgggac      300

ctgctcctgc ggtcgcccgc cggcgtgagc gcgactctgc ggcgggcaca gcccttggtc      360

accctgtgcc ggcgtccccg aggcggggga cggccggccg cgggcccggc tgccgccgcg      420

cgactccacc cgtggtgggg cgggggcggc tggccggcgg agcccctcgc gcggggcctg      480

tccagctctc cttcggagat cttgcaggag ctgggcaagg ggagcacgca tccgcagccc      540

ggggtgtcgc cacccgctgc cccggcggcg cccggcccca aggacggccc cggggagacg      600

gacgcgtttg gcaacagcga gggcaaagag ctggtggcct caggtgaaaa taaaataaaa      660

cagggtctgt tacctagctt ggaagatttg ctgttctata caattgctga aggacaagag      720

aaaatacctg ttcataaatt tattacagca ctcaaatcta caggattgcg aacgtctgat      780

cccaggttga aagagtgtat ggatatgtta agattaactc ttcaaacaac atcagatggt      840

gtcatgctag acaaagatct ttttaaaaaa tgtgttcaga gcaacattgt tttgttgaca      900

caagcattta gaagaaagtt tgtgattcct gactttatgt cttttacctc acacattgat      960

gagttatatg aaagtgctaa aaagcagtct ggaggaaagg ttgcagatta tattcctcaa     1020

ctggccaaat tcagtcccga tttgtggggt gtgtctgttt gtacagtaga tggacagagg     1080

cattctactg gagataccaa agttcccttc tgtcttcagt cctgtgtaaa acctttgaaa     1140

tatgccattg ctgttaatga tcttggaact gaatatgtgc atcgatatgt tggaaaagag     1200

ccgagtggac taagattcaa caaactattt ttgaatgaag atgataaacc acataatcct     1260

atggtaaatg ctggagcaat tgttgtgact tcactaataa agcaaggagt aaataatgct     1320

gaaaaatttg actatgtcat gcagtttttg aataagatgg ctggtaatga atatgttgga     1380

ttcagtaatg caacgtttca gtctgaaaga gaaagtggag atcgaaattt tgcaatagga     1440

tattacttaa aagaaaagaa gtgttttcca gaaggcacag acatggttgg tatattagac     1500

ttctacttcc agctgtgctc cattgaagtg acttgtgaat cagccagtgt gatggctgcg     1560

acactggcta atggtggttt ctgcccaatt actggtgaaa gagtactgag ccctgaagca     1620

gttcgaaata cattgagttt gatgcattcc tgtggcatgt atgacttctc agggcagttt     1680

gctttccatg ttggtcttcc tgcaaaatct ggagttgctg ggggcattct tttagttgtc     1740

cccaatgtta tgggtatgat gtgctggtct cctcctctgg ataagatggg caacagtgtt     1800

aagggaattc acttttgtca cgatcttgtt tctctgtgta atttccataa ctatgataat     1860

ttgagacact ttgcaaaaaa acttgatcct cgaagagaag gtggtgatca aagggtaaag     1920

tcagtgataa atcttttgtt tgctgcatat actggagatg tgtctgcact tcgaagattt     1980

gctttgtcag ctatggacat ggaacagcgg gactatgatt ctagaacagc actccatgta     2040

gctgctgcag agggtcatgt tgaagttgtt aaatttttgc tggaagcctg caaagtaaac     2100

cctttcccca aggacaggtg gaataacact cccatggatg aagcactgca ctttggacac     2160

catgatgtat ttaaaattct ccaagaatac caagtccagt acacacctca aggagattct     2220

gacaacggga aggaaaatca aaccgtccat aagaatcttg atggattgtt gtaatggtct     2280

caaatcccaa gatttaaatc acttacctat ttaattgtgg aaaatgatta tgaagaacat     2340

gtgtatttct atctggtagt gatgtatatt ttacatttgt catttcagtg ttactggagt     2400

tttcttcatt gtgcacacag gacaaatctg atctctttgg gaaaaaatag aaataaaaca     2460

atctccctcc ataatgtgag caatattacc tcgtgcattg tataatttga tgtaaaagaa     2520

atagttacca atgctagctt gtgtggtctt ccatgattta tttgtgtttt gtgaattttc     2580

aatttatggt gatgatctgc tgatatgcat ttataaagta agctctgttg tacagtctgt     2640

ccaaatgggt caaggttgcc tttagaagca aatagtgtga ttttcaagac ttcaaataca     2700

aatttagttt aagtgtttga acaactatat gcacttacgg ttgtgtgttt aaaatgtctc     2760

tctcaccccc tagcttcatg atgtgactct taaaaaacta taatagttaa caactgttag     2820

taagatagac caattctgat tagactttat cagggaatct gtttaagata tgtttggtga     2880

ccaaaacgta tgtgtgaatg tagttataat gcttttgaaa aattttcctt tttctatatc     2940

cccttagtcc agcctctctt ctcagacatt tagctatctg cctctttcct ttagctggga     3000

aagtgagagc tggcatacta tgcagttttt atgttttcca tagtaagtca gaaaatgcct     3060

cctatttctg gcatcagaac tttgccattt gtctacagaa gacgaaccag agacaaaatt     3120

actaagtata aattagtcaa gtttatcagt ctaaaaaacg aagggatgtg caactgcagc     3180

tctttaagaa gttttttttt tttagcttct agggtaaaga taaattcaga aatgctctaa     3240

gctaccaaag ttattctgaa agtatgggaa ctgctacaac taacaaacat ttgtttccaa     3300

gcctgtcatt aagagtctgc atcaagagat ttgtcctcct tgggggacca ctggatcatt     3360

ccagatttct tgtgattttt ctattgtgta attcttggtg ggctctgtag tttaataata     3420

agaaaaaggc catttcattt taaattgtga cctataattc tttgtcttgg gttggtaatt     3480

caggattcat ttggaaagtg ggtaaaaggg gcttcaaaaa acggatagaa caggattttc     3540

taggagttac acatacattt tatcctgtca tacctcgaga taaagtggca tgttagtgag     3600

gagttctgat attaagcaca cacacacatg cacacaaatg gacttctctg aagctgtgtt     3660

tagtgaaatg agctcaagta catgaatgtt agttgttatc acatacagca aattcctttt     3720

tttttctttt tctatgagca cactctgctg cttctaaact ttacatgcct gatggcacct     3780

tactccagca gcctccaggt gctttcattt tcacttccag tctaagccag tggctcctgc     3840

cactgccctc ccattaccta gatggcacct cctttggtga aaccacggcc aatgttcctt     3900

agctgcacca ggcccgaagc tgttcccatg cttgagcttc catggggagg atgctgagtg     3960

agcagtttcc taccccgtgg atctagcaag ccatggagac aggtagcatt tgtaagatgc     4020

tgcacaggag cagcattatc cccaaagata ttacagggta gacacgtttt aactgaaatc     4080

aatcaagata actttattca aagagcagcc cgctttgtgt gactaaaatg aaacaagaca     4140

gttgaattgt gtgacttgaa gattaccaat gattttgagg cttttctata ataaaaagag     4200

gttctaacca ttatttggga acaaagagag ttttcatctt ttttcagatc aaaaccattc     4260

tgtaaaatct ttgttgttta attaaatgtg ccgttattta cccctgatgt tatttatgac     4320

tatgtgccga ttcctgctcg ggctgtttgc tgttggctgg taataatata tttgatttaa     4380

atgctgttga ctgtgctatt aactgctgcc gtcagtaaac tccaaagatc tttttgtttt     4440

ggctttagta tcatatgtgc tttttctgta tcctgagcgc tctatatgat catgttaatt     4500

taaagcttta tacacattgt tgtttttgct ggtctcatct ttggtaatat gctatacccc     4560

actgctgccc gacactgccc tttagctgca gagctggatt agctgttgac catttgatgc     4620

tgttgtctgt ctggcaggga ctgaatgacc tgatgtcaga tttagattct tcctggggat     4680

tacacagcta tgaatgtatt tgcttctaaa acctcccaaa gtgaatctaa tcttaaaact     4740

acaagttgta agtattctga aattgggaaa catttatttt aaatgcaatc aggtagtgtt     4800

gctttttaca gcataataaa tatatgtatc aaaaaaaaaa aaaaaaaaaa                4850


<210>  1281
<211>  4962
<212>  DNA
<213>  homo sapiens

<400>  1281
cggaggcctc ggtttcgctg gagagaaaga gattgcgcag gcgcggagca gccgacgtgg       60

ccgcagggga ccgtgcctgg gggggtctgc gcggggccgc tgactcgcga ggttctctgt      120

cgcctgccgc cctcgctcct tttctcccct tctagagtgt tacggtgact cttgggtccg      180

aaggggacgg acgtcctccc acgtaccatt tagaagaaat ggagcaagag ccacaaaatg      240

gagaacctgc tgaaattaag atcatcagag aagcatataa gaaggccttt ttatttgtta      300

acaaaggtct gaatacagat gaattaggtc agaaggaaga agcaaagaac tactataagc      360

aaggaatagg acacctgctc agagggatca gcatttcatc aaaagagtct gaacacacag      420

gtcctgggtg ggaatctgct agacagatgc aacagaaaat gaaagaaact ctacagaatg      480

tacgcaccag gctggaaatt ctagagaagg gtcttgccac ttctctgcag aatgatcttc      540

aggaggtgcc caagttatat ccagaatttc cacctaaaga catgtgtgaa aaattaccag      600

agcctcagtc ttttagttca gctcctcagc atgctgaagt aaatggaaac acctcaactc      660

caagtgcagg ggcagttgct gcacctgctt ctctgtcttt accatcacaa agttgtccag      720

cagaagctcc tcctgcttat actcctcaag ctgctgaagg tcactacact gtatcctatg      780

gaacagattc tggggagttt tcatcagttg gagaggagtt ttataggaat cattctcagc      840

caccgcctct tgagacctta gggctggatg cagatgaatt gattttgata ccaaatggag      900

tacagatttt ttttgtaaat cctgcagggg aggttagtgc accttcgtat cctgggtacc      960

ttcgaattgt gaggtttttg gataattctc tcgatacggt tctaaaccgt cctcccgggt     1020

ttcttcaggt ttgtgactgg ttatatcctc tagttcctga tagatctccg gttctgaaat     1080

gtactgcggg agcctacatg tttcctgata caatgctaca agcagcagga tgctttgtgg     1140

gggtcgtcct gtcctctgag ttaccagagg atgatagaga gctctttgag gatctgttaa     1200

ggcaaatgtc tgaccttcgg ctccaggcca actggaacag agcagaagaa gaaaatgaat     1260

tccaaatccc tggaagaact agaccctcct ctgaccaact aaaagaagcc tctggcactg     1320

atgtgaaaca gttggaccaa ggcaataagg atgtacgtca taaaggaaaa cgtggaaaaa     1380

gggctaaaga tacttcaagt gaagaagtta acctgagtca cattgtacca tgtgagccag     1440

ttccagaaga aaagccaaaa gaattacctg aatggagtga aaaagtggct cacaacattt     1500

tgtcaggtgc ttcctgggtg agttggggtt tagtcaaagg tgctgagatt actggtaagg     1560

caatccagaa aggtgcttct aaactccgag agcggattca accagaagaa aaacccgtgg     1620

aagttagtcc agctgtcacc aagggacttt atatagcgaa gcaagctaca ggaggagcag     1680

caaaagtcag tcagttcctg gttgatggag tttgcactgt agcaaattgc gttggaaaag     1740

aactagctcc acatgtcaag aagcatggaa gcaaacttgt tccagaatct cttaaaaaag     1800

acaaagatgg gaaatctcct ctggatggtg ctatggttgt agcagcaagt agtgttcaag     1860

gattttcaac tgtctggcaa ggattggaat gtgcagctaa atgcatcgtt aacaatgttt     1920

cagcagaaac tgtacaaact gtcagataca aatacggata taatgcagga gaagctaccc     1980

accatgcggt ggattctgcg gtcaatgttg gcgtaactgc ctacaatatt aacaacattg     2040

gtatcaaagc aatggtgaag aaaactgcaa cacaaacagg acacactctc cttgaggact     2100

atcagatagt tgataattct cagagggaaa atcaagaagg agcagcaaat gtcaacgtga     2160

gaggggagaa ggatgagcag acgaaggaag taaaggaggc aaagaagaaa gataaatgat     2220

gaagtgctgg gaatcactta taccaaagcc ttatgaaatg gatgaaattt tgttaaatag     2280

gcaaatgtgg aattcctcac agattaacca gtatttttta aatgtattca ttcctacaaa     2340

ttaactttca taaattttat ggcatgtctt ctatttaaaa ggaaaagaat aagtattctt     2400

gcatctggcc ttagaaatgt gaagttatat tctcaagttt atttttttcc aagtgtagct     2460

aaaatatttt tgcaggtaaa ataaagctga tagtacatgt gttgttcaaa ccttgttaaa     2520

cctaatattg aactattttt atatctgctg tctttcagaa ggcaaatagg aaactatata     2580

tttgcttaaa aattggcatt tagtaacctt aattcttttt atagaaggaa tgacttaaag     2640

tattgtcccc tctttttgca ctaattgtgg atttttttag atgcttctca aaattttcag     2700

tgtgtaagct aaacaaaaac taaaactaag aattctcaaa aaaacttgtt caaaacaggg     2760

aaagactgat gaaaagtaaa atggactact tttgtaactt acctgtttgt taggaaatgg     2820

aatggtctct ttgatttaaa ataaataaaa atagattatt acgtcttttg tattgagact     2880

gtattgttat gagcctagga aatttgggaa catgattgta ttgtattaaa attcgaagtg     2940

attattatca gcttaattgg attaaaaaag tacttcaaga aattatttta tcatatctgc     3000

ttctgttttt ccaaaaggtt aaaacttgta aaaaaaatat atataaacaa ttgagtttac     3060

taatggtaaa catttttatt ctgggattcg gtcattggaa tttatattaa aagacaagtt     3120

attaaaaagg aaaggttcta ttcataatca gggtaaagaa tatgaaaacc ttagacgtaa     3180

tccatggtgg ataggcatta tggtttccac tttggcagaa ggcagactat tcacagccct     3240

atttacttac ataggctaaa aaactatgta actaaatacc taatggtatt taatttttgt     3300

ttattgaatt taagagattg gtattagttt tcatagctgt agtccattct aataatttct     3360

gatcttctag tggctactta attagacatt atttgaagct gtctgaagaa tgcactttat     3420

gaattaaaaa actgaattgc ctgacctcgt tatcacatga gcttatattt tgggaacaca     3480

tagaactgat ggaggctttt cctaaggcca aggataatgt actagttgtt aaaatggaaa     3540

taaaagtgaa gtggtaaata gcttacagac agtctatgct ttgtttaaga aatggaatgg     3600

cacttcatat attctcattt gtgggagcta aaaattacaa taatcaaact taaggagata     3660

gagagtagaa tgatggttac cagaggctgg gaggcattga agggatgggg agggaagtga     3720

ggttgattaa tgggtacgaa aatatagtta gaacgaattt gttgtagtat ttgatagccc     3780

aacagggtga ctacagtcaa caataacttt atacatttaa aaataaaaga gtgtaattgg     3840

gacgtttgta acacaaatga atgcttgaag cagtagatac accctgatgt aattattata     3900

aatcgcatac ctgtatcaaa atatctcatg tatcccataa atatatacac ctaccatgta     3960

cccataaaaa tttaaaaaga aatggaatgg caaataatgg aacataaact ttaaacagtt     4020

agctttgacc agaggtcagc aaatatcctc catgggctaa atccagatgt ccacctgttt     4080

tcataaataa cgttttattg gagcatagct gtacccattt gtttacatat tggctatggc     4140

tgctgtctag ttcaacgtga gagttgaata gttgcatcag agagtatatg gtccacaagc     4200

ctaacttatt cactctctgg ccctttgcag aaaaagtgtg ctgccttagt ctatagaaaa     4260

tggacttttc ccaccattca ctgactcatt aggagatagg catcttctaa agattttttt     4320

tatattgtgt aatgattgat atatagataa aattatatat tacttgtaag gtatgatgaa     4380

taacaacact taaaaactca tcacacctaa agacatggaa agctgccaat tacctatatg     4440

tatgttcttc ctattttctt acctctttcc ccatgtcatt ttttattgtt ccttgccatt     4500

ttttaatcac acatgtatgt tctccaaaca tactgtttca ttttttgaag ctttctacat     4560

atagtgtctg aatgtgaagt cttactcaac ttgctttttt gagtttatgt ttaaaattca     4620

ttcttgcgct tatatgcatg gatggtttac ttgctctata gtattctgtg tgagtatacc     4680

acaatttaag tgttcatttt cctatcagtt gacatttgtt tttagttttt gttggtagaa     4740

acagtacact caaaacatcc ttgactgtcc cctggtacac atatgcaaga gactttatgc     4800

gtaagagtgg agttgttggc ttgtcaagtt ttgcaaaata atgccaggta ttttccaaaa     4860

tgatgatatt ctcttgagta ttacttccct ttgcaatgtt tttattgtta atgtagcata     4920

tataaaaaag tatctcataa ttttaaaaaa aaaaaaaaaa aa                        4962


<210>  1282
<211>  4247
<212>  DNA
<213>  homo sapiens

<400>  1282
acggtagggg agcagagtgg gcaggccggg ggtgagggct cgcgctccgg gagctgcacg       60

gggctgcgtg gaaagagcgc cgagcggtgg cgtcgttgtc gccccctcct cgtcgggaag      120

aatcgtttgg tctcctgccg tgcccggaga atgtgtgtgt gtcccgggcc cagacgaatt      180

ggaatcccag tcagaagttc cagcctgcca ctgttctctg atgccatgcc agcaccaact      240

caactgtttt ttcctctcat ccgtaactgt gaactgagca ggatctatgg cactgcatgt      300

tactgccacc acaaacatct ctgttgttcc tcatcgtaca ttcctcagag tcgactgaga      360

tacacacctc atccagcata tgctaccttt tgcaggccaa aggagaactg gtggcagtac      420

acccaaggaa ggagatatgc ttccacacca cagaaatttt acctcacacc tccacaagtc      480

aatagcatcc ttaaagctaa tgaatacagt ttcaaagtgc cagaatttga cggcaaaaat      540

gtcagttcta tccttggatt tgacagcaat cagctgcctg caaatgcacc cattgaggac      600

cggagaagtg cagcaacctg cttgcagacc agagggatgc ttttgggggt ttttgatggc      660

catgcaggtt gtgcttgttc ccaggcagtc agtgaaagac tcttttatta tattgctgtc      720

tctttgttac cccatgagac tttgctagag attgaaaatg cagtggagag cggccgggca      780

ctgctaccca ttctccagtg gcacaagcac cccaatgatt actttagtaa ggaggcatcc      840

aaattgtact ttaacagctt gaggacttac tggcaagagc ttatagacct caacactggt      900

gagtcgactg atattgatgt taaggaggct ctaattaatg ccttcaagag gcttgataat      960

gacatctcct tggaggcgca agttggtgat cctaattctt ttctcaacta cctggtgctt     1020

cgagtggcat tttctggagc cactgcttgt gtggcccatg tggatggtgt tgaccttcat     1080

gtggccaata ctggcgatag cagagccatg ctgggtgtgc aggaagagga cggctcatgg     1140

tcagcagtca cgctgtctaa tgaccacaat gctcaaaatg aaagagaact agaacggctg     1200

aaattggaac atccaaagag tgaggccaag agtgtcgtga aacaggatcg gctgcttggc     1260

ttgctgatgc catttagggc atttggagat gtaaagttca aatggagcat tgaccttcaa     1320

aagagagtga tagaatctgg cccagaccag ttgaatgaca atgaatatac caagtttatt     1380

cctcctaatt atcacacacc tccttatctc actgctgagc cagaggtaac ttaccaccga     1440

ttaaggccac aggataagtt tctggtgttg gctactgatg ggttgtggga gactatgcat     1500

aggcaggatg tggttaggat tgtgggtgag tacctaactg gcatgcatca ccaacagcca     1560

atagctgttg gtggctacaa ggtgactctg ggacagatgc atggcctttt aacagaaagg     1620

agaaccaaaa tgtcctcggt atttgaggat cagaacgcag caacccatct cattcgccac     1680

gctgtgggca acaacgagtt tgggactgtt gatcatgagc gcctctctaa aatgcttagt     1740

cttcctgaag agcttgctcg aatgtacaga gatgacatta caatcattgt agttcagttc     1800

aattctcatg ttgtaggggc gtatcaaaac caagaatagt gagtggctct ttcactggca     1860

attctcaaat gatatacatt taaagggcag attttttaaa aagatactac tataataaac     1920

atttccagtt ggtcattcta agcatttacc cttttgatac tctagctagt caggtactcc     1980

aaattgactt tgcagcaggg tggcagggtc aggagagtct ggtcctgcct agctcagatt     2040

tcatggcacc tgcacttgaa gcaagtcact tctttatcac aggtgtcttg aaacattagc     2100

ttcttttacc aacctgagaa aattaggatg acctggcaaa taagatcttg aataggccaa     2160

aagcaagtat cttgctgtgt gtagtctctt ggttaaagtg aagaaacagt actgttcaca     2220

cctttcttca ctgagattcc agtgtacatg agaacatata tttattgcat gattttctag     2280

atacacagtc tatgcattat tcatatacat ttattttagc ctaaagtggt tttcaaatcc     2340

agttcttcaa gccataaatg accaagatcc aagcaatctg aatttgtttt tgtgattatt     2400

tgactggaat gcttcttaag tggaataact atactccgtt atccacccga tttcctaatg     2460

taattgaaag attttctatt ttgccacaca cttggagaca ataagggttt ttagttttat     2520

ctactcttct attgaagtta aagaaagaaa aaaagatttt tttatttgta ttaatgaaaa     2580

gctttagttt aaaataagga gatccagaat aaaaagaaga gactgatctc ttcaattatt     2640

gtcatctgta gccaccagca catcactctt atgtaatccc caaaggcttg gcatgccgta     2700

agtgtgtggt gggtagactg ctgccgggga atcgtacttc ttatttagta atgataagac     2760

ttttcattat ttttggaatt ttaaagatga cataaataag tttaaatatc aatttgggga     2820

gtaaggttta atattgccat cgggtattga gacaggagga agtttctgtt tttctccatt     2880

tagacatagg tcaattaaaa tatttgggtt taaaatgact aaatgcttta aacatattgt     2940

agcttaagat atatgtgtta agatatatac atgagaaact ttaaaaggta actactgtgc     3000

atgcctgatg cttaatagaa tacttagtgg catcaaatgt ttgcagcagt ctccataatt     3060

atattcagtc ccttctaata ctgtatcaat gtaaatgaaa taaatatatt caaattggct     3120

ttttgatatg catcaagtgg cattttgttc ctgtgtttaa tagtgatctg tatacagctg     3180

tgcacatatt gtcatcactt attctagcat cactgttaag gctgtgatta tgtttgatat     3240

tcacctggat tttaatacaa gccaatatca gcttcccatt gtgtaataac ttgggtgttt     3300

aggagtcttt tcacattttt tggggatatg aactagatgt tcaagaactc cttctggact     3360

gtggatactg aatcagtgta ctattggctg cagaatttgt ttcaattgaa aatagactca     3420

ggaagattgc tgctcagaat atcatataat gtttattttt tgaggtgttt ttgtttttat     3480

ttgtgtgttt tttttttttt aagtcagctt ggaacttttt tcctgggtag tatttgggag     3540

agggaaaggc tgtactatat atttatttct aaatgttttg actgggcatt tttcttttaa     3600

tgaaatatgt ggactgctct agcaaaccct attttcagct actatttgaa tattcttgaa     3660

caccaccact gaagagtttc atatacacca aataatgtct catctctata gtacagggaa     3720

tataaaattg gtttcctgtg gtcatgatca agatagtagt attattacac aagaaacttg     3780

gtctgcagtc tggaagcttg tctgctctat agaaatgaaa atgcagcatg aagttgacat     3840

tgtggaaatg aaagtaattg ggtattagaa atctgaaagt actgtcatct aaaagcaatt     3900

gtgattttat tgtaattggt tgtcactgtt gtacggtgtc tagaattaaa gaatacatgt     3960

aaactttcat ggtatttagc ctttcttaaa tttttttaaa atttaaactt tctaacctat     4020

gtattcaact tctgtattta tatttaatca gtggttcatg ttatataata cacccttaac     4080

tagttaaatg gaatgttggt atggtacaga gtaccatatt gctaagaaaa ctgtcttata     4140

aaagatgtat atgtgtgaag acatgaaagt ttaatgtaca gaatggttgg agaaatgcct     4200

atggtgaatt aaagcttcat atctgctttc tgaaaaaaaa aaaaaaa                   4247


<210>  1283
<211>  2125
<212>  DNA
<213>  homo sapiens

<400>  1283
cgacgacaag gatggggccc atctcttcgg agcctaagga tccagcccag gtccagccct       60

gcgcagccgc ccaccaagct gccagaagac gagccggacg cccaaggcta cgagaggacg      120

attgcagaat tgtacaggct agtggttggg gaatattttt tcgtggaagg gaccgtcttc      180

cttagctgtg gccctctcat caggtctggg aagaggtaat tggaaaatag aactcatgga      240

gaagtgttac cacaggccat ggacaaggcc agaatttccc tgacatctgt ccgccagcac      300

cgcccttcag gtacaattcc acaagagacc ccccaaactt gatgaagtca cccgcttaca      360

agggctcact ctccacctgc gcaaggactg caattcccag gggcctccag ggcacccggc      420

cgctccagtc cagtcgtgca ggcggcgcgc tctttctcgc tccgctcaag tccaggaacc      480

ggttcccggg ctcccagcct ctcggcagcg cccacgcgcc tgggccaaag tccgcgaacg      540

gaagccggcg gcgaggagga ttctgggagt tggaggccga ggctgcgacc tgcgcaggcg      600

caaacctgcc cctggggtga gggctgtaag tggcgcgatt cgcggcagcg ccccgatgga      660

acctcctggt cctgtgaggg ggcccttgca agattccagc tggtatgagc cttctgcaga      720

gctagtgcag actaggatgg ctgtatcact aacagcagct gaaactctgg cccttcaggg      780

tacacaggga caagagaaga tgatgatgat gggaccaaag gaagaggaac agtcttgtga      840

gtatgagacc aggctacctg ggaaccactc taccagtcaa gagatcttcc gccaacgctt      900

caggcatctc cgctaccagg agactcctgg tccccgggag gccttgagcc aactacgagt      960

actctgctgt gagtggctga ggccagagaa acacacgaag gagcagatcc tggagttcct     1020

ggtgctggaa caattcttga ccatcctgcc tgaggagctc caatcctggg tgcggggaca     1080

tcaccctaag agtggagagg aggctgtgac tgtgctggag gatttagaga aaggacttga     1140

accagagccg caggtcccag gccctgcaca tggacctgca caggaagagc catgggagaa     1200

gaaggaatct ctgggagcag cccaggaagc actgagcatc cagctccagc ctaaggagac     1260

ccagcctttc ccaaagagtg aacaggtata tttacatttt ctgtcagttg ttacagaaga     1320

tggcccagag cccaaggaca aaggatcatt gccacaacca cccattactg aagtggaatc     1380

acaggtgttc tcagaaaaac ttgctactga cacctctaca tttgaagcta cctctgaggg     1440

taccttagaa ctgcagcaga gaaatcccaa agcggagaga ctgaggtggt cccctgccca     1500

ggaggaaagt ttcaggcaga tggttgtcat ccataaggaa attcccacag ggaagaaaga     1560

ccatgaatgt agtgaatgtg gtaaaacctt catttataac tcacatcttg ttgtccacca     1620

gagagttcat tctggagaga aaccctataa gtgtagtgac tgtgggaaaa ctttcaaaca     1680

gagctcaaac ctcggtcagc atcagagaat tcatacagga gagaaaccct tcgaatgtaa     1740

tgaatgtggg aaggccttca gatggggtgc tcatcttgtt cagcatcaga ggattcactc     1800

aggagagaag ccctatgagt gtaatgagtg tgggaaggcc tttagtcaaa gctcatatct     1860

aagtcagcat cggagaattc acagtggaga gaaacctttt atatgtaaag aatgtgggaa     1920

agcttatgga tggtgctcag agctcattag acatcggaga gttcatgcca gaaaagagcc     1980

ttcccattga attgaagggg agaacgtctc cagacagaat tctacatcgg tctaatctac     2040

tttaggactg gatcccataa aagttataag ttccttaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaa                                           2125


<210>  1284
<211>  10619
<212>  DNA
<213>  homo sapiens

<400>  1284
aactccaccc cggggagctg ttgtgcttgc attgctgggc tgctgataga ctgattgagt       60

ggtggcgtgt acttttgtca caagaaccat aaccacaatg acagccacac agcatggacc      120

tagcgtgtgc tcagctctgg acaagacatg gatgtaggca gacatgcttc ctgcctgctg      180

ggcttagtgc accaatgcta aggacagaca tgaagggctt gggaaaggca tgaagatgca      240

gggagtctag gagagaggat aagaaaaaca agcattttgt ggtgggttga attgcgttgt      300

cgtttttaga ggcatttcgt gatccatggt tgcgctcccg tgaagagcga gtctagagaa      360

ggaatccgaa ggtgggtgag agttgaggga atttgaattc cataattacg actcgaattt      420

ctgcaatcag ctcgcggctg tgttgcctgc tcctgccaca aaaacgccat gcagcgccga      480

gccaagtcgg atggaagtgg gttagggtat tatataagcc cttgcgggag ggaagatggt      540

cttttatgtg tgtttctttt gcagcggcgg cggcgagcgc ggctcaggtt gatttagaat      600

acgggtgaca gtggcctggc gcgagcccac tgctgacgaa agcggcttat cccgcgcggt      660

ttccatggag acgagccgga gccgcggcgg cggcggggct gtcagcgagc gcggcggagc      720

tggcgcgtcc gtgggggtct gcaggaggaa ggcggaggcc ggggccggga ccgggaccct      780

cgcggcagac atggacttgc attgtgactg tgccgccgaa acgccggccg ccgagccgcc      840

gtcggggaag attaataaag ctgccttcaa attattcaag aagaggaaat cgggtggcac      900

catgcccagc atttttgggg tcaaaaacaa aggggacggg aaaagctcgg gtccgacggg      960

gctggtgagg agcaggaccc acgacggact tgccgaggtg ctggtgctgg agagcggcag     1020

gaaggaggag ccgcgcggcg ggggcgacag cggcgggggc ggcggggggc ggccgaaccc     1080

ggggcccccc agagccgcag ggcccggcgg gggctccctc gccagcagct cggtggccaa     1140

gtcgcacagc ttcttctcgc tgctgaagaa gaacgggcgc tcggaaaacg gcaagggaga     1200

gcctgtggac gcgagcaagg ccggcggcaa acaaaagcgg gggctgcggg ggctgttcag     1260

cggcatgcgc tggcacagga aagacaagcg ggccaaggcg gaggccgcgg aggggcgcgc     1320

gcccgggggc ggcttgatcc tacccggctc gctcaccgcc agcctggagt gcgtcaagga     1380

ggagacgccc agagccgcgc gcgagccgga ggagcccagc caggacgccc cgcgagaccc     1440

agcaggtgag cccgcagggg gagaggaggt gcccgccccc gccgaccgcg ccccagcgcg     1500

gagctgccga gaggcagagg gcctcgcgca ccccggcgac accggcgccc ggggagagga     1560

cgccgcgggg catcggcgcg ccgagccggg gcccggggag gtccgcacgg cagaggacgc     1620

ttccaggacg ggggccgttc ccgtaaagac ggtccccctt gtcgactccg aaggcggcag     1680

cggccgggcg cccgccgccc cagaccctgc ctctgtcgat ccaccctcag acccgtcggc     1740

agatcgtatt tgtttgatgt tttctgacgt gacttcactg aaaagctttg actctcttac     1800

aggctgtgga gatattattg cagaccaaga ggaagaggca ggtcccagct gtgacaagca     1860

tgtccccggg ccaggcaagc cggctctgtc taaaaagaac cccggcgtgg tggcctacca     1920

aggaggcggg gaagagatgg ccagcccgga cgaggtggac gacacctatc tacaggagtt     1980

ctgggacatg ctctcccaga ccgaggagca gggacccgag ccccaggagg gcgcggctaa     2040

ggtggcagct gcgctggaaa ccaaggtggt gcccgagacc cccaaagaca ccaggtgtgt     2100

ggaagcggcc aaggacgcgt cctcggtcaa gcgcaggagg ctcaaccgga ttcccatcga     2160

gccccatcct aaggaggagc ccaagcaccc ggagaaggag cagcaggaag gcgtccccaa     2220

cagcgacgag ggctactggg actccaccac gccaggccca gaggaagaca gctcgagcag     2280

cgggaagaag gcgggcatcc cccgggatag ctacagcggg gacgcgctct atgatctcta     2340

tgctgacccg gacggaagtc cagcaaccct tcctggaggg aaggacaacg aggagacgtc     2400

ctccctgtcc cggttaaagc ccgtatctcc aggcaccatc acctgtccac tgcgaacacc     2460

aggcagcttg ctgaaggact ctaagatccc tattagcatc aagcacctga ccaaccttcc     2520

atctagccat cccgtggtgc accagcaacc ctccaggagt gagatgccca gaacaaaaat     2580

cccggtttcc aaagtgctgg tccgcagagt cagcaaccgg ggcttggctg ggaccaccat     2640

cagagcaacg gcctgccacg acagtgccaa aaagttgtga ggtcttccag gccaaggtgg     2700

atgggcccca tgccaaggaa tacaactttt ccctggaaac cactaaagta agttttgctt     2760

ttcctaaaga aagtctttta ggacaccacc cgtcccccgc cctgctccag agcgtggacc     2820

gaggaggtct ttgtgccctg agcagggacc ggataacacc agaaagaggg atgctacacg     2880

ggggtttctc ctctcaagat aagtccctga gaattatttt caagcacttt tttctttttt     2940

acctttaagt ttttcttcct tttgctttaa tatactgaac acttggaagt cacctttact     3000

tgcctttgca gaaaacagaa cttagccaaa cctaagtaag agtcatgcct ggatattggg     3060

ataagccagt gtctagaggc ctgaaggaac cgctgaagaa ccagaggaga tctcctcttc     3120

caagacacgt ttccttcctt cccttctttc ctctttcctt tccagttaaa aaaaaacaaa     3180

aacaaaaaca aaaccctttg ctgtatcact gtgtggaaaa tacctccaaa gctgaaagag     3240

ccaggtattt acctgatgag cagaggggac cactgattgg cagaaaactt ccctacgttc     3300

agttgttaga tatgcaaatt gataaggatc taacactagg aaaataaagg cgagttttgg     3360

tttggttggt ttcagtcatt tgtttgggga gatataaaag gctcaggaga gcaggctttt     3420

gcttttgctt ttgtttgttt cttcccccac ccagtgcaga aatcaggatc agggaaagat     3480

tttattaaat gccaatagat acagtattta agcatttata aactgaaacc ttttcatgtg     3540

aagataatgc atattttacc gtttatccag ctgttaacat tttgtaatca gtcaattcaa     3600

tagaattatt ctggataatt ctatatctag aatataaaat ctggtcttat agctagacat     3660

gatgatggtc cccaaaccat tgatgttctg ttatgtactg taatgggaag cgattctgat     3720

tttgttttat atgggttctc tggttctcaa aaaaaaaaaa aatctattgt gctggtgtcc     3780

cagaggaatg gctctgcctt gttttgggta agagtctgtt tctcacccca aaccctgttt     3840

tcagattttt ttttaccttg attgtaaaat ttcagatcca accattcctc aatataatga     3900

gtgcaaaatg aggaacacat aaagaaaaac aatagaaaga tacagttttt cacatcattt     3960

gccttttgct ttatagactt atgacaaaga caagtgtgtt cagaatatga cactggcaag     4020

cttatgtatt gtaaacactt tatgccaagt tttttttgaa aagtggtttg cttctatgta     4080

tgttttctaa tatttcagat gaaacattta tttcagaaag ggttattata tgcctagttt     4140

gaatgataaa ctgaagcagt tcctagaatg ctattagtgt ctaatgatga aattaatatc     4200

ctttttgaaa tacacttcag tgtatttaat caaaagacca gagcttctac taggaggtga     4260

ttcatcatac caggaagatt atgcatattc acgtgaaact gcacatatgt aaatgacatg     4320

aacacttctg tataagtctc atttccagag agattgcatt agtaatgaac tgttattaca     4380

tgctttttaa gtttgttttc tgtttcataa atgaaagaac aaggcaagtt aaatatatga     4440

aaacctattt taataatatg aagaaagtaa caaaataaat ggacatcaaa ggaaagcaaa     4500

ttgagccagt agcagaaagt aggccattcc ccattttaaa tttgcagtga ttcaattagg     4560

agaggtttgc tgaatttctt cattagtcat atgactggct tttattgcat tgtctcagat     4620

ccataatgtt atttcaaagt aatcttttaa tatttaattt ctttatgtgt gtaaatgagg     4680

ccctatatgc agtcatagcc ttaagcattc tgaacacact accaagaatt catataagca     4740

tctcacactc acgtgctcat gcactcaact gtgtacagac taacagacaa aagacatcta     4800

ctctagatct ggaaattatt tttgaaatta tttctgtatt aaacaaggga tttacatttg     4860

atttcatgcc gctggtacta tttaggctca aaatacattc atcttcccct agtgaatgga     4920

gaaaatataa attttattcc tagctgtaaa acaaaggatc ttgatttcct tgttgtacat     4980

tttcctgcaa gggttatatt ctcctttgca tgaatccatg gcaaagttat gttggttcat     5040

ttgttcaatt gtacaggaaa gttaagaata cctgaaaaac ttatgagaat attgtaatag     5100

taaaggcaat ctatttctta agcagtagaa gaaaagtttt tgctttcata attttaggac     5160

ttaatcctcc atttacacca ttatgctgtg tctcctcttt ataagaaaag gaacacgtga     5220

gcaaagttta tcttaatttc cactgacctg tcaattaacc agttataaaa gatataaaat     5280

attttctttt aaaatttata ttttccactt tttttttacc ttatttttta agaattgcac     5340

ccacaccaat caaataaagg atttgggcaa tgaattaaac agcctcaatc acttgatggg     5400

aaatccctgg agtggcagga agagtagatt ctcaactttt tccaaccata gaaaagggat     5460

catagttgct ttcttgtgcc aagggctact ttctctcatt tgtgttcatg gagattgttt     5520

tttcaagaat tttcctagat ttacattcca atttttatta atacattata tctaatgacc     5580

ttgtgaagat tattcaggcc catatttgct gactttttaa gggaaggatt ggatagaggc     5640

taattatatc tttcccacat gtatgtatat tctaagatac ttggttgatt gacttccttt     5700

agttgaaagg ctgcccaaat tagacaggaa aaagtcaaat caattgttgg gcgaaaattt     5760

atcggttggt ttaatagctc tgcacaaaga cagcctgact tgaatgtcta tattacacat     5820

acactgttat ttgaaacact ctgctttagt acagatggtg gttgatgcgt ttatcctgcc     5880

attagcacca attgggagaa attttactac agcattttaa ataatcacaa gagtaaatag     5940

atttctatta ttttatctaa taacaacaat agaatataga atacaaagga cttcctctag     6000

atacatttta ttttatctaa taacaacaat ggaatataga atacaaagga cttcctttag     6060

atacattttc cacaaattat ctgcttattt aaatacaaag ggtttaatat ctatgaaggt     6120

aataactcac cgtgtttaaa ggatttattt cttcatctca gaggtagtct tcaagtattt     6180

gcagttaaac agtatgcaaa tagccctttg cttacacaat tatccaggta aaaagactat     6240

gtcaggtgtt gagatttctt tgaattttct aagagttttc attatttacg cctttgtcag     6300

attaatttta aaggcaactc ttgactgtta gcttggtgtg aagagatcca ctcaggcagc     6360

tcatgtctcc taagtgccct cagacagcag tgacgggaca cttcacatga cgctagcatg     6420

ttggctctgt ccgcatggcg gaatgcattc cctgctgtta gttatctgaa tttttctcct     6480

gaattacaaa tatatggatt tggctcccct gatgctgggc ttctgctgag acctgttcca     6540

gtacattcac gtatgctttg ctccccttca ttgttaagaa attaattcaa gaagtttttt     6600

gctgttaaac ataaggaata agcatcacaa ttgcctcatc tcatcactga ggaaagctgg     6660

tttaaagtat ctgagtgaaa taagaggaaa accccaaata cttcacctaa cccagtttcc     6720

ctttcccctc ctccaggcag agcaaggaaa agaacagttg taatttgtgt aaactcagcc     6780

ttagaaaatt tcaattcatt acacacaaaa atatttatga agcagtttgg aaccaaaggg     6840

gtagtatggt agacgagtgt cttacagagc ctgtgtgggg aagcaaaagg caagggtgta     6900

gttcacaggc agaagcgagc tgtgacattg tcagtgcagc gtgtaagtgt ggctcctcac     6960

aggcggccat tgattgtgag acctcatctt gctctgaaga tttcccggtg gctgtcatgc     7020

attgcttctc aaaagccttg cactgtgata aggtttaagg agacagattg ttgcaacaat     7080

agccacttct aaggaatgtt attatgtcac tgcagatgat gtttttaaga ggtgattcag     7140

aatgatagtt tcgtgattac ggaaaggagt tccttctcaa actgcaaaag gaaagatgaa     7200

aatagtcatg aagcctccag aactgaaatt gggcaccttt tatgatggat atttacttta     7260

attcaatgca acacatattt atggggcata gactgtatca aatacttaat aaaacccatt     7320

cagtttggag ctcacaccta agctgcgctg taattggatt ttcttaatat tcattaaaaa     7380

cacaaaacaa tattatttta cttttttttg gtatttgcat ttgttgctta tagtttgtgg     7440

ggtgaagcaa agtggtgtga agttgaagaa gggcactatg aattaagcca cacaaatgcc     7500

tctaaaaaat agtaaatgta acaatggtta acattcattg aatacttact atgtgtcagg     7560

cactgctagg agatttagaa ataattactt agtcctctta acagccatgt ggggtaggta     7620

atattatctc cccagtaaga cagctttaat tcatcctttt tgtttctatc cctttccatc     7680

tctgtctgtc tgtctctctc tctcttttcc cctagtctct aggacaggga tataaactct     7740

ttagtgattt tcagtaatag agagctaagc actgcttagt gtcattgtca gctcacttct     7800

aatagaaaga gctaacccat gtccacgcag ctgaaaatta gttttgtgtc tgagatgatg     7860

gtgctcacaa tcatatacag ggaaccctgc cactgtgcta tgctgagtag gcaaacattg     7920

gccttccctt ggagggatcc tcttctctta ggattaatgt gggaagtaca gacagaaatc     7980

tcttctgttg tcatggcgat acttcttccc tgacagggta tcattcattc aaagcatatt     8040

tgtttcattt gtttttattc ctaccttaag ccatcttggt gggttctggg tggtctatgc     8100

atatgtgtgt gtgttttaat tgcagtaaga atattgaata tgagatctac cctctttaat     8160

tttttttttt tttttttttg agatggagtc ttactctgtc acccaggctg gagtgcagtg     8220

gcttgatctc ggctcactat aacctccacc tcccaggttc aagtgattct cctgcctcag     8280

cctcccaagt agctgagact acaggcgtgc accaccatgc ccgttagttt ttgtattttt     8340

agtagagaca gggtttcacc atgttggcca ggctggtctc aaactcctga cctcaaatga     8400

tctgcccacc tctacctcca aagtgttggg attacaggca atgagccacc acgcccgggt     8460

taccttcttt aatttttaag tacacaatac agtattgtta actatagcca cagtgttgta     8520

cagcaaatct ctctcaccta tgcatcctgc gtaactgaaa ctctgtgccc attgaacagc     8580

agctcctcat ttcctccccc atcagcccct ggcagccatc attctactct ctgcttctgt     8640

gagtctggct attttagatc ccttatagaa gtggaaacgc gcagtatttg tccttctgtg     8700

actggcttat ttcattgagc ataacgaccc ccaagtttag ccatgttgtt gcttatggca     8760

ggatttcctt cttttttcag gctgaataat atttccttat atgtatatgc tgcattttta     8820

aaaacccttt catctactga cagacgttta gattatttcc acatcttggc tattatgagt     8880

aatgctacaa cgaacgaggg agtgaaaata tctctttaag atcctgattt cagttttttt     8940

gaataaatac ccagaagtgg aatgactggg tcattcatat ggtaattcta attaaacata     9000

gaattatttt taattttttg agaaacttct gtgctgcttt ccacagtggt tgcatctgtt     9060

tacatactta ccaatggtgc acaagggttc caatttctcc acatctttgc caacttgtta     9120

tctgtgtttg tttaaatgac agctgtatga gttgtccctt gcctccatgc aattctgaac     9180

ttcagaaata agcacttggc tcctttaata gctgtccgtc ctatgttgtg tctacagcca     9240

ctgaatcctg tcctacattt tctgattcat taactcattc aactaatagc tattgaacac     9300

catcaataag tcagccacca tgaagatgag tattttatat tgaattctac taacatatcc     9360

tgtatgttta ctatgttgcc agagaggatg ctgtgtgctt tttttacatt gttatcttta     9420

ctcttcacaa gaaccatgta aggtaggtat tggtaaaatg ggtaattttg gaaatgcttc     9480

aataatcgag tagaataact tttgctctat gtgagaagat acgttttaaa taagatatgg     9540

cttaggtttc tggttacctg agacatacta taccttctca gatactctca gacctgaatc     9600

atttaacaaa ctaaggcaga aatactaaaa atatctggtt caataacata ggggcatgga     9660

gtagacatgc agaaaatgct tgttcacttg ccttgaaatg gctccaggtg gcctgaagga     9720

atcaatgaaa cttctcaagt atctacatta caaccactgg tccccactac acatttattt     9780

ctaaataaag gaggagaaac tctagcaaag taatatttaa cattttcatt gcttccagga     9840

taaatcttat tgaatatgga ggatctgata gtggtaggtc tatcaggaat atcagggaaa     9900

atgcttttga tgttgttggc aaagtcaatt cctatcattt gtacttgaca ccagctacct     9960

agcaggctca ttgtgaactt caggtttcgc ccacgttatt tatataaagt atctcagtgt    10020

aatataggga gttgctggtt atttgaaaat agtaacaaaa ataacccaaa cgagaaactc    10080

catttccata attagctttc ctgaaagtca ggcatgtctt tgaggacagg ttttggcagt    10140

attatttttg tgcacaggag gaaaattgtt agtaggttta tagatgttat ttttataata    10200

gaatgttaaa cccctgaaaa acatcaaaaa ttgtctccta gaactaattc tatgttttaa    10260

aaacttgttt taaaaaggat tctaaatagc aatagggtct ttcctccttt ctccactcca    10320

atggtttaat gggatagagg aatcaatgtt tatattttta aacctgtaaa tattttattt    10380

tgggtatttt gtatatttgt tgatataatt ccattttgtg catatgtacc attgtgcatg    10440

ttgctgtttt tgatagtcac tcttttaatg aatgtaagaa gcttgggcta atagcacttt    10500

tcttgttcca ttcaaacatc tgaaaatgaa attacaacac tgccatttta ctgttgtgtt    10560

taattcagtc aataaatttt gttgctcctt tgcatttaaa gtgaaaaaaa aaaaaaaaa     10619


<210>  1285
<211>  9953
<212>  DNA
<213>  homo sapiens

<400>  1285
gacctagcgt gtgctcagct ctggacaaga catggatgta ggcagacatg cttcctgcct       60

gctgggctta gtgcaccaat gctaaggaca gacatgaagg gcttgggaaa ggcatgaaga      120

tgcagggagt ctaggagaga ggataagaaa aacaagcatt ttgtggtggg ttgaattgcg      180

ttgtcgtttt tagaggcatt tcgtgatcca tggttgcgct cccgtgaaga gcgagtctag      240

agaaggaatc cgaagcggcg gcggcgagcg cggctcaggt tgatttagaa tacgggtgac      300

agtggcctgg cgcgagccca ctgctgacga aagcggctta tcccgcgcgg tttccatgga      360

gacgagccgg agccgcggcg gcggcggggc tgtcagcgag cgcggcggag ctggcgcgtc      420

cgtgggggtc tgcaggagga aggcggaggc cggggccggg accgggaccc tcgcggcaga      480

catggacttg cattgtgact gtgccgccga aacgccggcc gccgagccgc cgtcggggaa      540

gattaataaa gctgccttca aattattcaa gaagaggaaa tcgggtggca ccatgcccag      600

catttttggg gtcaaaaaca aaggggacgg gaaaagctcg ggtccgacgg ggctggtgag      660

gagcaggacc cacgacggac ttgccgaggt gctggtgctg gagagcggca ggaaggagga      720

gccgcgcggc gggggcgaca gcggcggggg cggcgggggg cggccgaacc cggggccccc      780

cagagccgca gggcccggcg ggggctccct cgccagcagc tcggtggcca agtcgcacag      840

cttcttctcg ctgctgaaga agaacgggcg ctcggaaaac ggcaagggag agcctgtgga      900

cgcgagcaag gccggcggca aacaaaagcg ggggctgcgg gggctgttca gcggcatgcg      960

ctggcacagg aaagacaagc gggccaaggc ggaggccgcg gaggggcgcg cgcccggggg     1020

cggcttgatc ctacccggct cgctcaccgc cagcctggag tgcgtcaagg aggagacgcc     1080

cagagccgcg cgcgagccgg aggagcccag ccaggacgcc ccgcgagacc cagcaggctg     1140

tggagatatt attgcagacc aagaggaaga ggcaggtccc agctgtgaca agcatgtccc     1200

cgggccaggc aagccggctc tgtctaaaaa gaaccccggc gtggtggcct accaaggagg     1260

cggggaagag atggccagcc cggacgaggt ggacgacacc tatctacagg agttctggga     1320

catgctctcc cagaccgagg agcagggacc cgagccccag gagggcgcgg ctaaggtggc     1380

agctgcgctg gaaaccaagg tggtgcccga gacccccaaa gacaccaggt gtgtggaagc     1440

ggccaaggac gcgtcctcgg tcaagcgcag gaggctcaac cggattccca tcgagcccca     1500

tcctaaggag gagcccaagc acccggagaa ggagcagcag gaaggcgtcc ccaacagcga     1560

cgagggctac tgggactcca ccacgccagg cccagaggaa gacagctcga gcagcgggaa     1620

gaaggcgggc atcccccggg atagctacag cggggacgcg ctctatgatc tctatgctga     1680

cccggacgga agtccagcaa cccttcctgg agggaaggac aacgaggaga cgtcctccct     1740

gtcccggtta aagcccgtat ctccaggcac catcacctgt ccactgcgaa caccaggcag     1800

cttgctgaag gactctaaga tccctattag catcaagcac ctgaccaacc ttccatctag     1860

ccatcccgtg gtgcaccagc aaccctccag gagtgagatg cccagaacaa aaatcccggt     1920

ttccaaagtg ctggtccgca gagtcagcaa ccggggcttg gctgggacca ccatcagagc     1980

aacggcctgc cacgacagtg ccaaaaagtt gtgaggtctt ccaggccaag gtggatgggc     2040

cccatgccaa ggaatacaac ttttccctgg aaaccactaa agtaagtttt gcttttccta     2100

aagaaagtct tttaggacac cacccgtccc ccgccctgct ccagagcgtg gaccgaggag     2160

gtctttgtgc cctgagcagg gaccggataa caccagaaag agggatgcta cacgggggtt     2220

tctcctctca agataagtcc ctgagaatta ttttcaagca cttttttctt ttttaccttt     2280

aagtttttct tccttttgct ttaatatact gaacacttgg aagtcacctt tacttgcctt     2340

tgcagaaaac agaacttagc caaacctaag taagagtcat gcctggatat tgggataagc     2400

cagtgtctag aggcctgaag gaaccgctga agaaccagag gagatctcct cttccaagac     2460

acgtttcctt ccttcccttc tttcctcttt cctttccagt taaaaaaaaa caaaaacaaa     2520

aacaaaaccc tttgctgtat cactgtgtgg aaaatacctc caaagctgaa agagccaggt     2580

atttacctga tgagcagagg ggaccactga ttggcagaaa acttccctac gttcagttgt     2640

tagatatgca aattgataag gatctaacac taggaaaata aaggcgagtt ttggtttggt     2700

tggtttcagt catttgtttg gggagatata aaaggctcag gagagcaggc ttttgctttt     2760

gcttttgttt gtttcttccc ccacccagtg cagaaatcag gatcagggaa agattttatt     2820

aaatgccaat agatacagta tttaagcatt tataaactga aaccttttca tgtgaagata     2880

atgcatattt taccgtttat ccagctgtta acattttgta atcagtcaat tcaatagaat     2940

tattctggat aattctatat ctagaatata aaatctggtc ttatagctag acatgatgat     3000

ggtccccaaa ccattgatgt tctgttatgt actgtaatgg gaagcgattc tgattttgtt     3060

ttatatgggt tctctggttc tcaaaaaaaa aaaaaatcta ttgtgctggt gtcccagagg     3120

aatggctctg ccttgttttg ggtaagagtc tgtttctcac cccaaaccct gttttcagat     3180

ttttttttac cttgattgta aaatttcaga tccaaccatt cctcaatata atgagtgcaa     3240

aatgaggaac acataaagaa aaacaataga aagatacagt ttttcacatc atttgccttt     3300

tgctttatag acttatgaca aagacaagtg tgttcagaat atgacactgg caagcttatg     3360

tattgtaaac actttatgcc aagttttttt tgaaaagtgg tttgcttcta tgtatgtttt     3420

ctaatatttc agatgaaaca tttatttcag aaagggttat tatatgccta gtttgaatga     3480

taaactgaag cagttcctag aatgctatta gtgtctaatg atgaaattaa tatccttttt     3540

gaaatacact tcagtgtatt taatcaaaag accagagctt ctactaggag gtgattcatc     3600

ataccaggaa gattatgcat attcacgtga aactgcacat atgtaaatga catgaacact     3660

tctgtataag tctcatttcc agagagattg cattagtaat gaactgttat tacatgcttt     3720

ttaagtttgt tttctgtttc ataaatgaaa gaacaaggca agttaaatat atgaaaacct     3780

attttaataa tatgaagaaa gtaacaaaat aaatggacat caaaggaaag caaattgagc     3840

cagtagcaga aagtaggcca ttccccattt taaatttgca gtgattcaat taggagaggt     3900

ttgctgaatt tcttcattag tcatatgact ggcttttatt gcattgtctc agatccataa     3960

tgttatttca aagtaatctt ttaatattta atttctttat gtgtgtaaat gaggccctat     4020

atgcagtcat agccttaagc attctgaaca cactaccaag aattcatata agcatctcac     4080

actcacgtgc tcatgcactc aactgtgtac agactaacag acaaaagaca tctactctag     4140

atctggaaat tatttttgaa attatttctg tattaaacaa gggatttaca tttgatttca     4200

tgccgctggt actatttagg ctcaaaatac attcatcttc ccctagtgaa tggagaaaat     4260

ataaatttta ttcctagctg taaaacaaag gatcttgatt tccttgttgt acattttcct     4320

gcaagggtta tattctcctt tgcatgaatc catggcaaag ttatgttggt tcatttgttc     4380

aattgtacag gaaagttaag aatacctgaa aaacttatga gaatattgta atagtaaagg     4440

caatctattt cttaagcagt agaagaaaag tttttgcttt cataatttta ggacttaatc     4500

ctccatttac accattatgc tgtgtctcct ctttataaga aaaggaacac gtgagcaaag     4560

tttatcttaa tttccactga cctgtcaatt aaccagttat aaaagatata aaatattttc     4620

ttttaaaatt tatattttcc actttttttt taccttattt tttaagaatt gcacccacac     4680

caatcaaata aaggatttgg gcaatgaatt aaacagcctc aatcacttga tgggaaatcc     4740

ctggagtggc aggaagagta gattctcaac tttttccaac catagaaaag ggatcatagt     4800

tgctttcttg tgccaagggc tactttctct catttgtgtt catggagatt gttttttcaa     4860

gaattttcct agatttacat tccaattttt attaatacat tatatctaat gaccttgtga     4920

agattattca ggcccatatt tgctgacttt ttaagggaag gattggatag aggctaatta     4980

tatctttccc acatgtatgt atattctaag atacttggtt gattgacttc ctttagttga     5040

aaggctgccc aaattagaca ggaaaaagtc aaatcaattg ttgggcgaaa atttatcggt     5100

tggtttaata gctctgcaca aagacagcct gacttgaatg tctatattac acatacactg     5160

ttatttgaaa cactctgctt tagtacagat ggtggttgat gcgtttatcc tgccattagc     5220

accaattggg agaaatttta ctacagcatt ttaaataatc acaagagtaa atagatttct     5280

attattttat ctaataacaa caatagaata tagaatacaa aggacttcct ctagatacat     5340

tttattttat ctaataacaa caatggaata tagaatacaa aggacttcct ttagatacat     5400

tttccacaaa ttatctgctt atttaaatac aaagggttta atatctatga aggtaataac     5460

tcaccgtgtt taaaggattt atttcttcat ctcagaggta gtcttcaagt atttgcagtt     5520

aaacagtatg caaatagccc tttgcttaca caattatcca ggtaaaaaga ctatgtcagg     5580

tgttgagatt tctttgaatt ttctaagagt tttcattatt tacgcctttg tcagattaat     5640

tttaaaggca actcttgact gttagcttgg tgtgaagaga tccactcagg cagctcatgt     5700

ctcctaagtg ccctcagaca gcagtgacgg gacacttcac atgacgctag catgttggct     5760

ctgtccgcat ggcggaatgc attccctgct gttagttatc tgaatttttc tcctgaatta     5820

caaatatatg gatttggctc ccctgatgct gggcttctgc tgagacctgt tccagtacat     5880

tcacgtatgc tttgctcccc ttcattgtta agaaattaat tcaagaagtt ttttgctgtt     5940

aaacataagg aataagcatc acaattgcct catctcatca ctgaggaaag ctggtttaaa     6000

gtatctgagt gaaataagag gaaaacccca aatacttcac ctaacccagt ttccctttcc     6060

cctcctccag gcagagcaag gaaaagaaca gttgtaattt gtgtaaactc agccttagaa     6120

aatttcaatt cattacacac aaaaatattt atgaagcagt ttggaaccaa aggggtagta     6180

tggtagacga gtgtcttaca gagcctgtgt ggggaagcaa aaggcaaggg tgtagttcac     6240

aggcagaagc gagctgtgac attgtcagtg cagcgtgtaa gtgtggctcc tcacaggcgg     6300

ccattgattg tgagacctca tcttgctctg aagatttccc ggtggctgtc atgcattgct     6360

tctcaaaagc cttgcactgt gataaggttt aaggagacag attgttgcaa caatagccac     6420

ttctaaggaa tgttattatg tcactgcaga tgatgttttt aagaggtgat tcagaatgat     6480

agtttcgtga ttacggaaag gagttccttc tcaaactgca aaaggaaaga tgaaaatagt     6540

catgaagcct ccagaactga aattgggcac cttttatgat ggatatttac tttaattcaa     6600

tgcaacacat atttatgggg catagactgt atcaaatact taataaaacc cattcagttt     6660

ggagctcaca cctaagctgc gctgtaattg gattttctta atattcatta aaaacacaaa     6720

acaatattat tttacttttt tttggtattt gcatttgttg cttatagttt gtggggtgaa     6780

gcaaagtggt gtgaagttga agaagggcac tatgaattaa gccacacaaa tgcctctaaa     6840

aaatagtaaa tgtaacaatg gttaacattc attgaatact tactatgtgt caggcactgc     6900

taggagattt agaaataatt acttagtcct cttaacagcc atgtggggta ggtaatatta     6960

tctccccagt aagacagctt taattcatcc tttttgtttc tatccctttc catctctgtc     7020

tgtctgtctc tctctctctt ttcccctagt ctctaggaca gggatataaa ctctttagtg     7080

attttcagta atagagagct aagcactgct tagtgtcatt gtcagctcac ttctaataga     7140

aagagctaac ccatgtccac gcagctgaaa attagttttg tgtctgagat gatggtgctc     7200

acaatcatat acagggaacc ctgccactgt gctatgctga gtaggcaaac attggccttc     7260

ccttggaggg atcctcttct cttaggatta atgtgggaag tacagacaga aatctcttct     7320

gttgtcatgg cgatacttct tccctgacag ggtatcattc attcaaagca tatttgtttc     7380

atttgttttt attcctacct taagccatct tggtgggttc tgggtggtct atgcatatgt     7440

gtgtgtgttt taattgcagt aagaatattg aatatgagat ctaccctctt taattttttt     7500

tttttttttt tttgagatgg agtcttactc tgtcacccag gctggagtgc agtggcttga     7560

tctcggctca ctataacctc cacctcccag gttcaagtga ttctcctgcc tcagcctccc     7620

aagtagctga gactacaggc gtgcaccacc atgcccgtta gtttttgtat ttttagtaga     7680

gacagggttt caccatgttg gccaggctgg tctcaaactc ctgacctcaa atgatctgcc     7740

cacctctacc tccaaagtgt tgggattaca ggcaatgagc caccacgccc gggttacctt     7800

ctttaatttt taagtacaca atacagtatt gttaactata gccacagtgt tgtacagcaa     7860

atctctctca cctatgcatc ctgcgtaact gaaactctgt gcccattgaa cagcagctcc     7920

tcatttcctc ccccatcagc ccctggcagc catcattcta ctctctgctt ctgtgagtct     7980

ggctatttta gatcccttat agaagtggaa acgcgcagta tttgtccttc tgtgactggc     8040

ttatttcatt gagcataacg acccccaagt ttagccatgt tgttgcttat ggcaggattt     8100

ccttcttttt tcaggctgaa taatatttcc ttatatgtat atgctgcatt tttaaaaacc     8160

ctttcatcta ctgacagacg tttagattat ttccacatct tggctattat gagtaatgct     8220

acaacgaacg agggagtgaa aatatctctt taagatcctg atttcagttt ttttgaataa     8280

atacccagaa gtggaatgac tgggtcattc atatggtaat tctaattaaa catagaatta     8340

tttttaattt tttgagaaac ttctgtgctg ctttccacag tggttgcatc tgtttacata     8400

cttaccaatg gtgcacaagg gttccaattt ctccacatct ttgccaactt gttatctgtg     8460

tttgtttaaa tgacagctgt atgagttgtc ccttgcctcc atgcaattct gaacttcaga     8520

aataagcact tggctccttt aatagctgtc cgtcctatgt tgtgtctaca gccactgaat     8580

cctgtcctac attttctgat tcattaactc attcaactaa tagctattga acaccatcaa     8640

taagtcagcc accatgaaga tgagtatttt atattgaatt ctactaacat atcctgtatg     8700

tttactatgt tgccagagag gatgctgtgt gcttttttta cattgttatc tttactcttc     8760

acaagaacca tgtaaggtag gtattggtaa aatgggtaat tttggaaatg cttcaataat     8820

cgagtagaat aacttttgct ctatgtgaga agatacgttt taaataagat atggcttagg     8880

tttctggtta cctgagacat actatacctt ctcagatact ctcagacctg aatcatttaa     8940

caaactaagg cagaaatact aaaaatatct ggttcaataa cataggggca tggagtagac     9000

atgcagaaaa tgcttgttca cttgccttga aatggctcca ggtggcctga aggaatcaat     9060

gaaacttctc aagtatctac attacaacca ctggtcccca ctacacattt atttctaaat     9120

aaaggaggag aaactctagc aaagtaatat ttaacatttt cattgcttcc aggataaatc     9180

ttattgaata tggaggatct gatagtggta ggtctatcag gaatatcagg gaaaatgctt     9240

ttgatgttgt tggcaaagtc aattcctatc atttgtactt gacaccagct acctagcagg     9300

ctcattgtga acttcaggtt tcgcccacgt tatttatata aagtatctca gtgtaatata     9360

gggagttgct ggttatttga aaatagtaac aaaaataacc caaacgagaa actccatttc     9420

cataattagc tttcctgaaa gtcaggcatg tctttgagga caggttttgg cagtattatt     9480

tttgtgcaca ggaggaaaat tgttagtagg tttatagatg ttatttttat aatagaatgt     9540

taaacccctg aaaaacatca aaaattgtct cctagaacta attctatgtt ttaaaaactt     9600

gttttaaaaa ggattctaaa tagcaatagg gtctttcctc ctttctccac tccaatggtt     9660

taatgggata gaggaatcaa tgtttatatt tttaaacctg taaatatttt attttgggta     9720

ttttgtatat ttgttgatat aattccattt tgtgcatatg taccattgtg catgttgctg     9780

tttttgatag tcactctttt aatgaatgta agaagcttgg gctaatagca cttttcttgt     9840

tccattcaaa catctgaaaa tgaaattaca acactgccat tttactgttg tgtttaattc     9900

agtcaataaa ttttgttgct cctttgcatt taaagtgaaa aaaaaaaaaa aaa            9953


<210>  1286
<211>  10619
<212>  DNA
<213>  homo sapiens

<400>  1286
aactccaccc cggggagctg ttgtgcttgc attgctgggc tgctgataga ctgattgagt       60

ggtggcgtgt acttttgtca caagaaccat aaccacaatg acagccacac agcatggacc      120

tagcgtgtgc tcagctctgg acaagacatg gatgtaggca gacatgcttc ctgcctgctg      180

ggcttagtgc accaatgcta aggacagaca tgaagggctt gggaaaggca tgaagatgca      240

gggagtctag gagagaggat aagaaaaaca agcattttgt ggtgggttga attgcgttgt      300

cgtttttaga ggcatttcgt gatccatggt tgcgctcccg tgaagagcga gtctagagaa      360

ggaatccgaa ggtgggtgag agttgaggga atttgaattc cataattacg actcgaattt      420

ctgcaatcag ctcgcggctg tgttgcctgc tcctgccaca aaaacgccat gcagcgccga      480

gccaagtcgg atggaagtgg gttagggtat tatataagcc cttgcgggag ggaagatggt      540

cttttatgtg tgtttctttt gcagcggcgg cggcgagcgc ggctcaggtt gatttagaat      600

acgggtgaca gtggcctggc gcgagcccac tgctgacgaa agcggcttat cccgcgcggt      660

ttccatggag acgagccgga gccgcggcgg cggcggggct gtcagcgagc gcggcggagc      720

tggcgcgtcc gtgggggtct gcaggaggaa ggcggaggcc ggggccggga ccgggaccct      780

cgcggcagac atggacttgc attgtgactg tgccgccgaa acgccggccg ccgagccgcc      840

gtcggggaag attaataaag ctgccttcaa attattcaag aagaggaaat cgggtggcac      900

catgcccagc atttttgggg tcaaaaacaa aggggacggg aaaagctcgg gtccgacggg      960

gctggtgagg agcaggaccc acgacggact tgccgaggtg ctggtgctgg agagcggcag     1020

gaaggaggag ccgcgcggcg ggggcgacag cggcgggggc ggcggggggc ggccgaaccc     1080

ggggcccccc agagccgcag ggcccggcgg gggctccctc gccagcagct cggtggccaa     1140

gtcgcacagc ttcttctcgc tgctgaagaa gaacgggcgc tcggaaaacg gcaagggaga     1200

gcctgtggac gcgagcaagg ccggcggcaa acaaaagcgg gggctgcggg ggctgttcag     1260

cggcatgcgc tggcacagga aagacaagcg ggccaaggcg gaggccgcgg aggggcgcgc     1320

gcccgggggc ggcttgatcc tacccggctc gctcaccgcc agcctggagt gcgtcaagga     1380

ggagacgccc agagccgcgc gcgagccgga ggagcccagc caggacgccc cgcgagaccc     1440

agcaggtgag cccgcagggg gagaggaggt gcccgccccc gccgaccgcg ccccagcgcg     1500

gagctgccga gaggcagagg gcctcgcgca ccccggcgac accggcgccc ggggagagga     1560

cgccgcgggg catcggcgcg ccgagccggg gcccggggag gtccgcacgg cagaggacgc     1620

ttccaggacg ggggccgttc ccgtaaagac ggtccccctt gtcgactccg aaggcggcag     1680

cggccgggcg cccgccgccc cagaccctgc ctctgtcgat ccaccctcag acccgtcggc     1740

agatcgtatt tgtttgatgt tttctgacgt gacttcactg aaaagctttg actctcttac     1800

aggctgtgga gatattattg cagaccaaga ggaagaggca ggtcccagct gtgacaagca     1860

tgtccccggg ccaggcaagc cggctctgtc taaaaagaac cccggcgtgg tggcctacca     1920

aggaggcggg gaagagatgg ccagcccgga cgaggtggac gacacctatc tacaggagtt     1980

ctgggacatg ctctcccaga ccgaggagca gggacccgag ccccaggagg gcgcggctaa     2040

ggtggcagct gcgctggaaa ccaaggtggt gcccgagacc cccaaagaca ccaggtgtgt     2100

ggaagcggcc aaggacgcgt cctcggtcaa gcgcaggagg ctcaaccgga ttcccatcga     2160

gccccatcct aaggaggagc ccaagcaccc ggagaaggag cagcaggaag gcgtccccaa     2220

cagcgacgag ggctactggg actccaccac gccaggccca gaggaagaca gctcgagcag     2280

cgggaagaag gcgggcatcc cccgggatag ctacagcggg gacgcgctct atgatctcta     2340

tgctgacccg gacggaagtc cagcaaccct tcctggaggg aaggacaacg aggagacgtc     2400

ctccctgtcc cggttaaagc ccgtatctcc aggcaccatc acctgtccac tgcgaacacc     2460

aggcagcttg ctgaaggact ctaagatccc tattagcatc aagcacctga ccaaccttcc     2520

atctagccat cccgtggtgc accagcaacc ctccaggagt gagatgccca gaacaaaaat     2580

cccggtttcc aaagtgctgg tccgcagagt cagcaaccgg ggcttggctg ggaccaccat     2640

cagagcaacg gcctgccacg acagtgccaa aaagttgtga ggtcttccag gccaaggtgg     2700

atgggcccca tgccaaggaa tacaactttt ccctggaaac cactaaagta agttttgctt     2760

ttcctaaaga aagtctttta ggacaccacc cgtcccccgc cctgctccag agcgtggacc     2820

gaggaggtct ttgtgccctg agcagggacc ggataacacc agaaagaggg atgctacacg     2880

ggggtttctc ctctcaagat aagtccctga gaattatttt caagcacttt tttctttttt     2940

acctttaagt ttttcttcct tttgctttaa tatactgaac acttggaagt cacctttact     3000

tgcctttgca gaaaacagaa cttagccaaa cctaagtaag agtcatgcct ggatattggg     3060

ataagccagt gtctagaggc ctgaaggaac cgctgaagaa ccagaggaga tctcctcttc     3120

caagacacgt ttccttcctt cccttctttc ctctttcctt tccagttaaa aaaaaacaaa     3180

aacaaaaaca aaaccctttg ctgtatcact gtgtggaaaa tacctccaaa gctgaaagag     3240

ccaggtattt acctgatgag cagaggggac cactgattgg cagaaaactt ccctacgttc     3300

agttgttaga tatgcaaatt gataaggatc taacactagg aaaataaagg cgagttttgg     3360

tttggttggt ttcagtcatt tgtttgggga gatataaaag gctcaggaga gcaggctttt     3420

gcttttgctt ttgtttgttt cttcccccac ccagtgcaga aatcaggatc agggaaagat     3480

tttattaaat gccaatagat acagtattta agcatttata aactgaaacc ttttcatgtg     3540

aagataatgc atattttacc gtttatccag ctgttaacat tttgtaatca gtcaattcaa     3600

tagaattatt ctggataatt ctatatctag aatataaaat ctggtcttat agctagacat     3660

gatgatggtc cccaaaccat tgatgttctg ttatgtactg taatgggaag cgattctgat     3720

tttgttttat atgggttctc tggttctcaa aaaaaaaaaa aatctattgt gctggtgtcc     3780

cagaggaatg gctctgcctt gttttgggta agagtctgtt tctcacccca aaccctgttt     3840

tcagattttt ttttaccttg attgtaaaat ttcagatcca accattcctc aatataatga     3900

gtgcaaaatg aggaacacat aaagaaaaac aatagaaaga tacagttttt cacatcattt     3960

gccttttgct ttatagactt atgacaaaga caagtgtgtt cagaatatga cactggcaag     4020

cttatgtatt gtaaacactt tatgccaagt tttttttgaa aagtggtttg cttctatgta     4080

tgttttctaa tatttcagat gaaacattta tttcagaaag ggttattata tgcctagttt     4140

gaatgataaa ctgaagcagt tcctagaatg ctattagtgt ctaatgatga aattaatatc     4200

ctttttgaaa tacacttcag tgtatttaat caaaagacca gagcttctac taggaggtga     4260

ttcatcatac caggaagatt atgcatattc acgtgaaact gcacatatgt aaatgacatg     4320

aacacttctg tataagtctc atttccagag agattgcatt agtaatgaac tgttattaca     4380

tgctttttaa gtttgttttc tgtttcataa atgaaagaac aaggcaagtt aaatatatga     4440

aaacctattt taataatatg aagaaagtaa caaaataaat ggacatcaaa ggaaagcaaa     4500

ttgagccagt agcagaaagt aggccattcc ccattttaaa tttgcagtga ttcaattagg     4560

agaggtttgc tgaatttctt cattagtcat atgactggct tttattgcat tgtctcagat     4620

ccataatgtt atttcaaagt aatcttttaa tatttaattt ctttatgtgt gtaaatgagg     4680

ccctatatgc agtcatagcc ttaagcattc tgaacacact accaagaatt catataagca     4740

tctcacactc acgtgctcat gcactcaact gtgtacagac taacagacaa aagacatcta     4800

ctctagatct ggaaattatt tttgaaatta tttctgtatt aaacaaggga tttacatttg     4860

atttcatgcc gctggtacta tttaggctca aaatacattc atcttcccct agtgaatgga     4920

gaaaatataa attttattcc tagctgtaaa acaaaggatc ttgatttcct tgttgtacat     4980

tttcctgcaa gggttatatt ctcctttgca tgaatccatg gcaaagttat gttggttcat     5040

ttgttcaatt gtacaggaaa gttaagaata cctgaaaaac ttatgagaat attgtaatag     5100

taaaggcaat ctatttctta agcagtagaa gaaaagtttt tgctttcata attttaggac     5160

ttaatcctcc atttacacca ttatgctgtg tctcctcttt ataagaaaag gaacacgtga     5220

gcaaagttta tcttaatttc cactgacctg tcaattaacc agttataaaa gatataaaat     5280

attttctttt aaaatttata ttttccactt tttttttacc ttatttttta agaattgcac     5340

ccacaccaat caaataaagg atttgggcaa tgaattaaac agcctcaatc acttgatggg     5400

aaatccctgg agtggcagga agagtagatt ctcaactttt tccaaccata gaaaagggat     5460

catagttgct ttcttgtgcc aagggctact ttctctcatt tgtgttcatg gagattgttt     5520

tttcaagaat tttcctagat ttacattcca atttttatta atacattata tctaatgacc     5580

ttgtgaagat tattcaggcc catatttgct gactttttaa gggaaggatt ggatagaggc     5640

taattatatc tttcccacat gtatgtatat tctaagatac ttggttgatt gacttccttt     5700

agttgaaagg ctgcccaaat tagacaggaa aaagtcaaat caattgttgg gcgaaaattt     5760

atcggttggt ttaatagctc tgcacaaaga cagcctgact tgaatgtcta tattacacat     5820

acactgttat ttgaaacact ctgctttagt acagatggtg gttgatgcgt ttatcctgcc     5880

attagcacca attgggagaa attttactac agcattttaa ataatcacaa gagtaaatag     5940

atttctatta ttttatctaa taacaacaat agaatataga atacaaagga cttcctctag     6000

atacatttta ttttatctaa taacaacaat ggaatataga atacaaagga cttcctttag     6060

atacattttc cacaaattat ctgcttattt aaatacaaag ggtttaatat ctatgaaggt     6120

aataactcac cgtgtttaaa ggatttattt cttcatctca gaggtagtct tcaagtattt     6180

gcagttaaac agtatgcaaa tagccctttg cttacacaat tatccaggta aaaagactat     6240

gtcaggtgtt gagatttctt tgaattttct aagagttttc attatttacg cctttgtcag     6300

attaatttta aaggcaactc ttgactgtta gcttggtgtg aagagatcca ctcaggcagc     6360

tcatgtctcc taagtgccct cagacagcag tgacgggaca cttcacatga cgctagcatg     6420

ttggctctgt ccgcatggcg gaatgcattc cctgctgtta gttatctgaa tttttctcct     6480

gaattacaaa tatatggatt tggctcccct gatgctgggc ttctgctgag acctgttcca     6540

gtacattcac gtatgctttg ctccccttca ttgttaagaa attaattcaa gaagtttttt     6600

gctgttaaac ataaggaata agcatcacaa ttgcctcatc tcatcactga ggaaagctgg     6660

tttaaagtat ctgagtgaaa taagaggaaa accccaaata cttcacctaa cccagtttcc     6720

ctttcccctc ctccaggcag agcaaggaaa agaacagttg taatttgtgt aaactcagcc     6780

ttagaaaatt tcaattcatt acacacaaaa atatttatga agcagtttgg aaccaaaggg     6840

gtagtatggt agacgagtgt cttacagagc ctgtgtgggg aagcaaaagg caagggtgta     6900

gttcacaggc agaagcgagc tgtgacattg tcagtgcagc gtgtaagtgt ggctcctcac     6960

aggcggccat tgattgtgag acctcatctt gctctgaaga tttcccggtg gctgtcatgc     7020

attgcttctc aaaagccttg cactgtgata aggtttaagg agacagattg ttgcaacaat     7080

agccacttct aaggaatgtt attatgtcac tgcagatgat gtttttaaga ggtgattcag     7140

aatgatagtt tcgtgattac ggaaaggagt tccttctcaa actgcaaaag gaaagatgaa     7200

aatagtcatg aagcctccag aactgaaatt gggcaccttt tatgatggat atttacttta     7260

attcaatgca acacatattt atggggcata gactgtatca aatacttaat aaaacccatt     7320

cagtttggag ctcacaccta agctgcgctg taattggatt ttcttaatat tcattaaaaa     7380

cacaaaacaa tattatttta cttttttttg gtatttgcat ttgttgctta tagtttgtgg     7440

ggtgaagcaa agtggtgtga agttgaagaa gggcactatg aattaagcca cacaaatgcc     7500

tctaaaaaat agtaaatgta acaatggtta acattcattg aatacttact atgtgtcagg     7560

cactgctagg agatttagaa ataattactt agtcctctta acagccatgt ggggtaggta     7620

atattatctc cccagtaaga cagctttaat tcatcctttt tgtttctatc cctttccatc     7680

tctgtctgtc tgtctctctc tctcttttcc cctagtctct aggacaggga tataaactct     7740

ttagtgattt tcagtaatag agagctaagc actgcttagt gtcattgtca gctcacttct     7800

aatagaaaga gctaacccat gtccacgcag ctgaaaatta gttttgtgtc tgagatgatg     7860

gtgctcacaa tcatatacag ggaaccctgc cactgtgcta tgctgagtag gcaaacattg     7920

gccttccctt ggagggatcc tcttctctta ggattaatgt gggaagtaca gacagaaatc     7980

tcttctgttg tcatggcgat acttcttccc tgacagggta tcattcattc aaagcatatt     8040

tgtttcattt gtttttattc ctaccttaag ccatcttggt gggttctggg tggtctatgc     8100

atatgtgtgt gtgttttaat tgcagtaaga atattgaata tgagatctac cctctttaat     8160

tttttttttt tttttttttg agatggagtc ttactctgtc acccaggctg gagtgcagtg     8220

gcttgatctc ggctcactat aacctccacc tcccaggttc aagtgattct cctgcctcag     8280

cctcccaagt agctgagact acaggcgtgc accaccatgc ccgttagttt ttgtattttt     8340

agtagagaca gggtttcacc atgttggcca ggctggtctc aaactcctga cctcaaatga     8400

tctgcccacc tctacctcca aagtgttggg attacaggca atgagccacc acgcccgggt     8460

taccttcttt aatttttaag tacacaatac agtattgtta actatagcca cagtgttgta     8520

cagcaaatct ctctcaccta tgcatcctgc gtaactgaaa ctctgtgccc attgaacagc     8580

agctcctcat ttcctccccc atcagcccct ggcagccatc attctactct ctgcttctgt     8640

gagtctggct attttagatc ccttatagaa gtggaaacgc gcagtatttg tccttctgtg     8700

actggcttat ttcattgagc ataacgaccc ccaagtttag ccatgttgtt gcttatggca     8760

ggatttcctt cttttttcag gctgaataat atttccttat atgtatatgc tgcattttta     8820

aaaacccttt catctactga cagacgttta gattatttcc acatcttggc tattatgagt     8880

aatgctacaa cgaacgaggg agtgaaaata tctctttaag atcctgattt cagttttttt     8940

gaataaatac ccagaagtgg aatgactggg tcattcatat ggtaattcta attaaacata     9000

gaattatttt taattttttg agaaacttct gtgctgcttt ccacagtggt tgcatctgtt     9060

tacatactta ccaatggtgc acaagggttc caatttctcc acatctttgc caacttgtta     9120

tctgtgtttg tttaaatgac agctgtatga gttgtccctt gcctccatgc aattctgaac     9180

ttcagaaata agcacttggc tcctttaata gctgtccgtc ctatgttgtg tctacagcca     9240

ctgaatcctg tcctacattt tctgattcat taactcattc aactaatagc tattgaacac     9300

catcaataag tcagccacca tgaagatgag tattttatat tgaattctac taacatatcc     9360

tgtatgttta ctatgttgcc agagaggatg ctgtgtgctt tttttacatt gttatcttta     9420

ctcttcacaa gaaccatgta aggtaggtat tggtaaaatg ggtaattttg gaaatgcttc     9480

aataatcgag tagaataact tttgctctat gtgagaagat acgttttaaa taagatatgg     9540

cttaggtttc tggttacctg agacatacta taccttctca gatactctca gacctgaatc     9600

atttaacaaa ctaaggcaga aatactaaaa atatctggtt caataacata ggggcatgga     9660

gtagacatgc agaaaatgct tgttcacttg ccttgaaatg gctccaggtg gcctgaagga     9720

atcaatgaaa cttctcaagt atctacatta caaccactgg tccccactac acatttattt     9780

ctaaataaag gaggagaaac tctagcaaag taatatttaa cattttcatt gcttccagga     9840

taaatcttat tgaatatgga ggatctgata gtggtaggtc tatcaggaat atcagggaaa     9900

atgcttttga tgttgttggc aaagtcaatt cctatcattt gtacttgaca ccagctacct     9960

agcaggctca ttgtgaactt caggtttcgc ccacgttatt tatataaagt atctcagtgt    10020

aatataggga gttgctggtt atttgaaaat agtaacaaaa ataacccaaa cgagaaactc    10080

catttccata attagctttc ctgaaagtca ggcatgtctt tgaggacagg ttttggcagt    10140

attatttttg tgcacaggag gaaaattgtt agtaggttta tagatgttat ttttataata    10200

gaatgttaaa cccctgaaaa acatcaaaaa ttgtctccta gaactaattc tatgttttaa    10260

aaacttgttt taaaaaggat tctaaatagc aatagggtct ttcctccttt ctccactcca    10320

atggtttaat gggatagagg aatcaatgtt tatattttta aacctgtaaa tattttattt    10380

tgggtatttt gtatatttgt tgatataatt ccattttgtg catatgtacc attgtgcatg    10440

ttgctgtttt tgatagtcac tcttttaatg aatgtaagaa gcttgggcta atagcacttt    10500

tcttgttcca ttcaaacatc tgaaaatgaa attacaacac tgccatttta ctgttgtgtt    10560

taattcagtc aataaatttt gttgctcctt tgcatttaaa gtgaaaaaaa aaaaaaaaa     10619


<210>  1287
<211>  4417
<212>  DNA
<213>  homo sapiens

<400>  1287
ctccttcctg caagaagcgt tgcccgttgg ctagctgctc ggtggggatc tgcctgccct       60

gggggcgccg cccgcgctcc ccgcggtgct ctcgctcctg ggctgcgcca gtccgaggcg      120

gtgccggctc ctttgcctcc ccgagtcgca gatgctgcgg gcgcctccgg gaaaagatct      180

gggcggcgcg ctcgctcgat ggacacagga agatccagaa gctagtggca catctagcaa      240

cagagccaga tcagaaccca ggttggaggt ggagtagttc agaatcaact gacgcagccg      300

ggaattgagc tttgcaaagc cacttgcaag gaagggaagc atctgcccaa ccctccccca      360

ccgcgcgccc tggatcctct gcctgccccc tcccccgtga cgtcacccta gtcctgtccc      420

ggggagcctg caaagcctct cagattcaaa ctgctagacg cactgctgcc accgccaccg      480

aattggaaac gcgcgcccag gctccgtcgt cgccttcgcc cgccgaccgg gccagccggc      540

tctccgacct ccctacagaa tcgcacccca gtccctccct ggcagctcgg cttccctcag      600

ctccaactct tctcttccgc tcctgcctcc tgtcggattt ttaatttctg cgcaccccca      660

gtcaaattaa atcaaccaac aaaaagcagg gcatcccccc tggaagcagc gtcttatttt      720

accttgttct cccacttcct gaagatgcta aactcctggt ggactgcaga ggagagggat      780

tcagtcttct cctgatgtcg attgcgattt ctgctgggag ctcaagacgg gcgagctgcc      840

cgagatctct tcgagatacc ccaggggagg aggagatggg caggatttag taggacaact      900

cggttactaa tgacttggcg gctggctgcg accccccggg aaatcaggtt tgcctgtagg      960

tacctgagtt gacaccgaag gtgcctaaag atgctgagcg gcgtttggtt cctcagtgtg     1020

ttaaccgtgg ccgggatctt acagacagag agtcgcaaaa ctgccaaaga catttgcaag     1080

atccgctgtc tgtgcgaaga aaaggaaaac gtactgaata tcaactgtga gaacaaagga     1140

tttacaacag ttagcctgct ccagcccccc cagtatcgaa tctatcagct ttttctcaat     1200

ggaaacctct tgacaagact gtatccaaac gaatttgtca attactccaa cgcggtgact     1260

cttcacctag gtaacaacgg gttacaggag atccgaacgg gggcattcag tggcctgaaa     1320

actctcaaaa gactgcatct caacaacaac aagcttgaga tattgaggga ggacaccttc     1380

ctaggcctgg agagcctgga gtatctccag gccgactaca attacatcag tgccatcgag     1440

gctggggcat tcagcaaact taacaagctc aaagtgctca tcctgaatga caaccttctg     1500

ctttcactgc ccagcaatgt gttccgcttt gtcctgctga cccacttaga cctcaggggg     1560

aataggctaa aagtaatgcc ttttgctggc gtccttgaac atattggagg gatcatggag     1620

attcagctgg aggaaaatcc atggaattgc acttgtgact tacttcctct caaggcctgg     1680

ctagacacca taactgtttt tgtgggagag attgtctgtg agactccctt taggttgcat     1740

gggaaagacg tgacccagct gaccaggcaa gacctctgtc ccagaaaaag tgccagtgat     1800

tccagtcaga ggggcagcca tgctgacacc cacgtccaaa ggctgtcacc tacaatgaat     1860

cctgctctca acccaaccag ggctccgaaa gccagccggc cgcccaaaat gagaaatcgt     1920

ccaactcctc gagtgactgt gtcaaaggac aggcaaagtt ttggacccat catggtgtac     1980

cagaccaagt ctcctgtgcc tctcacctgt cccagcagct gtgtctgcac ctctcagagc     2040

tcagacaatg gtctgaatgt aaactgccaa gaaaggaagt tcactaatat ctctgacctg     2100

cagcccaaac cgaccagtcc aaagaaactc tacctaacag ggaactatct tcaaactgtc     2160

tataagaatg acctcttaga atacagttct ttggacttac tgcacttagg aaacaacagg     2220

attgcagtca ttcaggaagg tgcctttaca aacctgacca gtttacgcag actttatctg     2280

aatggcaatt accttgaagt gctgtaccct tctatgtttg atggactgca gagcttgcaa     2340

tatctctatt tagagtataa tgtcattaag gaaattaagc ctctgacctt tgatgctttg     2400

attaacctac agctactgtt tctgaacaac aaccttcttc ggtccttacc tgataatata     2460

tttgggggga cggccctaac caggctgaat ctgagaaaca accatttttc tcacctgccc     2520

gtgaaagggg ttctggatca gctcccggct ttcatccaga tagatctgca ggagaacccc     2580

tgggactgta cctgtgacat catggggctg aaagactgga cagaacatgc caattcccct     2640

gtcatcatta atgaggtgac ttgcgaatct cctgctaagc atgcagggga gatactaaaa     2700

tttctgggga gggaggctat ctgtccagac agcccaaact tgtcagatgg aaccgtcttg     2760

tcaatgaatc acaatacaga cacacctcgg tcgcttagtg tgtctcctag ttcctatcct     2820

gaactacaca ctgaagttcc actgtctgtc ttaattctgg gattgcttgt tgttttcatc     2880

ttatctgtct gttttggggc tggtttattc gtctttgtct tgaaacgccg aaagggagtg     2940

ccgagcgttc ccaggaatac caacaactta gacgtaagct cctttcaatt acagtatggg     3000

tcttacaaca ctgagactca cgataaaaca gacggccatg tctacaacta tatcccccca     3060

cctgtgggtc agatgtgcca aaaccccatc tacatgcaga aggaaggaga cccagtagcc     3120

tattaccgaa acctgcaaga gttcagctat agcaacctgg aggagaaaaa agaagagcca     3180

gccacacctg cttacacaat aagtgccact gagctgctag aaaagcaggc cacaccaaga     3240

gagcctgagc tgctgtatca aaatattgct gagcgagtca aggaacttcc cagcgcaggc     3300

ctagtccact ataacttttg taccttacct aaaaggcagt ttgccccttc ctatgaatct     3360

cgacgccaaa accaagacag aatcaataaa accgttttat atggaactcc caggaaatgc     3420

tttgtggggc agtcaaaacc caaccaccct ttactgcaag ctaagccgca atcagaaccg     3480

gactacctcg aagttctgga aaaacaaact gcaatcagtc agctgtgaag ggaaatcatt     3540

tacaacccta aggcatcaga ggatgctgct ccgaactgtt ggaaacaagg acattagctt     3600

ttgtgtttgt ttttgttctc cctttcccag tgttaatggg ggactttgaa aatgtttggg     3660

agataggatg aagtcatgat tttgcttttg caagttttcc tttaaattat ttctctctcg     3720

ctctcctccc ctcctttttt tttttttttt ttttttcttt ttcccttctc ttcttaggaa     3780

ccatcagtgg acatgaatgt ttctacaatg catttcttca tagattttgt ttatggtttt     3840

gtttcttttt tcttctttgt ttttcagtgt gggagtggga agaggagatt atagtgactg     3900

aagaaagaat aggcaaactt ttcaaatgaa aatggatatt tagtgtattt tgtagaagat     3960

ctccaaagat cttttgtgac tacaacttct tttgtaaata atgatatatg gtatttccat     4020

cgtcagttac cgagtatagc cactgggtat cactactttg tgttaaagtg ccttcgcact     4080

ttaagtacat tacttaaatg ttgcttttag ctttgataaa ttgaaaatat tttaatgtgt     4140

tgtatttttg aaattgaaaa cactgtaaaa tagattgatg tgtcagctat attaagtcaa     4200

cgtacagttt gcttgagtta tagaaaccag cctgtcatca aatgattcta gttctaggac     4260

tttgtaggct taactataaa atatttcctt tcctctgggt ttaagtgatt ttatttaagt     4320

caactaaggg gatttaacag tggactagag gtaataagcc acctcagtca ggattaataa     4380

ttcattaata aaatatattt aacccaaaaa aaaaaaa                              4417


<210>  1288
<211>  2559
<212>  DNA
<213>  homo sapiens

<400>  1288
ctccctcccg ccggccgggg tgcgcgggcg gcggggcggc ccgcgggcca tgcgttcggc       60

gcggcccagc ccggccggcc gggggcggcg ccccgagccc gggccccgcg cggcccgcgc      120

ccccggcccc cgctgagccc cgggggcccc gctgcggccg aggccatgtt cccggtgttt      180

ccttgcacgc tgctggcccc ccccttcccc gtgctgggcc tggactcccg gggggtgggc      240

ggcctcatga actccttccc gccacctcag ggtcacgccc agaaccccct gcaggtcggg      300

gctgagctcc agtcccgctt ctttgcctcc cagggctgcg cccagagtcc attccaggcc      360

gcgccggcgc ccccgcccac gccccaggcc ccggcggccg agcccctcca ggtggacttg      420

ctcccggtgc tcgccgccgc ccaggagtcc gccgcggctg ctgcggccgc tgccgccgct      480

gctgccgccg tcgctgccgc gcccccggcc cctgccgccg cctctacggt ggacacagcg      540

gccctgaagc agcctccggc gccccctccg ccacccccgc cagtgtcggc gcccgcggcc      600

gaggccgcgc cccccgcctc cgccgccact atcgccgcgg cggcggccac cgccgtcgta      660

gccccaacct cgacggtcgc cgtggccccg gtcgcgtctg ccttggagaa gaagacaaag      720

agcaaggggc cctacatctg cgctctgtgc gccaaggagt tcaagaacgg ctacaatctc      780

cggaggcacg aagccatcca cacgggagcc aaggccggcc gggtcccctc gggtgctatg      840

aagatgccga ccatggtgcc cctgagcctc ctgagcgtgc cccagctgag cggagccggc      900

gggggagggg gagaggcggg tgccggcggc ggcgctgccg cagtggccgc cggtggcgtg      960

gtgaccacga ccgcctcggg gaagcgcatc cggaagaacc atgcctgcga gatgtgtggc     1020

aaggccttcc gcgacgtcta ccacctgaac cgacacaagc tgtcgcactc ggacgagaag     1080

ccctaccagt gcccggtgtg ccagcagcgc ttcaagcgca aggaccgcat gagctaccac     1140

gtgcgctcac atgacggcgc tgtgcacaag ccctacaact gctcccactg tggcaagagc     1200

ttctcccggc cggatcacct caacagtcac gtcagacaag tgcactcaac agaacggccc     1260

ttcaaatgtg agaaatgtga ggcagctttc gccacgaagg atcggctgcg ggcgcacaca     1320

gtacgacacg aggagaaagt gccatgtcac gtgtgtggca agatgctgag ctcggcttat     1380

atttcggacc acatgaaggt gcacagccag ggtcctcacc atgtctgtga gctctgcaac     1440

aaaggtactg gtgaggtttg tccaatggcg gcggcagcgg cagcggcggc agcggcagca     1500

gcggcagcag tagcagcccc tcccacagct gtgggctccc tctcgggggc ggagggggtg     1560

cctgtgagct ctcagccact tccctcccaa ccctggtgag ctccaagttg gttgcggggg     1620

agaggggaga atggagtaga gtcccttggt acaagctcct ctcccccctc ttttcccacc     1680

aactcctatt tccctaccaa ccaaggagcc tccagaagga aaggaggaag aaatgttttc     1740

ttaggggaat tcgctaggtt ttaacgattt gtttctcctg ctcctcttct atcagacctg     1800

accccacaca aacctgtccc ctcggttgtg ttgaagtccc ctggacagtg ggcaggggtg     1860

gcagaggaca cgagcagcca ctgcccgtac cccctctcct ctctgtaagc ccatgccctg     1920

tcttcccagg gacttgtgag cctcttccct cgacggtcct cttctctcct tccagtcctc     1980

tccccctgct gtctgcagcc cctccccggg gagttggtgc tttcttttcc tttttttttt     2040

ttttccaggg ggagggagga gaggaaggag ggggatcaga gctgtcccaa agagggaaag     2100

cggtgaggtt tgaggagggg cagaagcagg gccggcaaag gttgtacctt cataaggtgg     2160

tatggggggt tggggtcagg ccctgaacat cgtcctactt gagaatctgt caggggaaaa     2220

agtcaagggg agcaggagga agagccagga gggccagagg cagagaagag atggagtctt     2280

aggggccagg gtgagcgagg ggtccagggc ctagaggtgc ttcctggggg cgggggaatg     2340

cagccagtgt ccccctcccc tcttccaccc cagctccagc cctggtcttg tcttttcatc     2400

cctcttcccc acgacagaag aagttgtggc cctggccatg tcatcgtgtt cctgtgtccc     2460

ctgcatgtac cccaccctcc accccttcct tttgcgcgga ccccattaca ataaatttta     2520

aataaaatcc tgtttctggc tctggattga aaaaaaaaa                            2559


<210>  1289
<211>  1661
<212>  DNA
<213>  homo sapiens

<400>  1289
tcgccaagcg actaaagctg gaagggaggg ggcggggttg tgagcaaatc ttggtggtgg       60

tggtggtggg gcggcctgag aagatatcat ggctgctgcc acggagctta atcgcccgag      120

cagcggtgac aggaacctgg agcgaagatg cagacccaac ctctcccgag aggtgctcta      180

cgaaatcttt cgctccctac acaccctggt tggacagctt gacctcagag atgatgtggt      240

gaaaattaca atcgattgga acaagctcca gagcctctcg gcattccagc ctgcattgct      300

ctttagtgca cttgaacaac acattttata tttacagcct tttttagcaa aacttcagtc      360

tccgattaaa gaggagaata caactgctgt tgaagagata ggaagaacag aaatggggaa      420

caaaaatgaa gtaaatgaca aattttccat tggcgaccta caagaggaag aaaagcacaa      480

agaaagtgat ttaagagatg tgaaaaagac acagatccat tttgatccag aagtagttca      540

gataaaggct ggaaaagcag aaattgacag acgaatatct gcatttattg aaagaaagca      600

agctgaaatc aatgaaaaca acgtcaggga attttgcaat gttattgatt gtaatcaaga      660

aaatagttgt gcaagaactg atgcgatttt taccccttac cccggattta aaagtcacgt      720

aaaagtttct agagttgtga atacatacgg accacagact agacctgaag gaattccagg      780

gtcaggtcat aaacctaaca gcatgcttcg agactgtggt aatcaggctg tagaagaacg      840

actacaaaat attgaggccc acttgcggtt acagacaggt ggtccagtgc caagagacat      900

ttatcagaga attaaaaaac ttgaggataa aatccttgaa ttggaaggca tctctcctga      960

atattttcag tctgtaagct tttctggaaa aagaagaaaa gttcaaccac ctcaacagaa     1020

ctattcactg gctgaacttg atgagaaaat tagtgccctc aaacaagccc tcctcagaaa     1080

atcaagagaa gcagaatcca tggcaaccca ccaccttcca tgaaaaactc ctctcatcct     1140

tgtcatttta cttttttgta tacatatgtg taacttacac tgttattaat tcaacggata     1200

tatatttatc aatgtagact tctctgtgaa gtcaaggttt attttcacat gagtccagct     1260

tgcagcaagt aatcttcaaa tattccagta agttttgaaa taatgaatgc attgaaaata     1320

gcattgttgg aatttattcc cttctgtttt aaaggaggta ttttggaaat tgaaaaactt     1380

aatttacaag tgctggtaca tcttttttct tttgtggacc acaggaagga agatttattt     1440

tgatattgat actttaaaag gactttatat ttgtaacatt gatgttaacc agtttattag     1500

tttaaatcag tactttgcat ataataagca ttcaacaaaa atttattgac tgaaatgaat     1560

tttaaatgca tgtgtatgaa cttgtttttc ttaatcttta agatgtcagt attcatgtaa     1620

ataaacaata gatccagctt tatcccttaa aaaaaaaaaa a                         1661


<210>  1290
<211>  1658
<212>  DNA
<213>  homo sapiens

<400>  1290
tcgccaagcg actaaagctg gaagggaggg ggcggggttg tgagcaaatc ttggtggtgg       60

tggtggtggg gcggcctgag aagatatcat ggctgctgcc acggagctta atcgcccgag      120

cagcggtgac aggaacctgg agcgaagatg cagacccaac ctctcccgag aggtgctcta      180

cgaaatcttt cgctccctac acaccctggt tggacagctt gacctcagag atgatgtggt      240

gaaaattaca atcgattgga acaagctcca gagcctctcg gcattccagc ctgcattgct      300

ctttagtgca cttgaacaac acattttata tttacagcct tttttagcaa aacttcagtc      360

tccgattaaa gaggagaata caactgctgt tgaagagata ggaagaacag aaatggggaa      420

caaaaatgaa gtaaatgaca aattttccat tggcgaccta caagaggaag aaaagcacaa      480

agaaagtgat ttaagagatg tgaaaaagac acagatccat tttgatccag aagtagttca      540

gataaaggct ggaaaagcag aaattgacag acgaatatct gcatttattg aaagaaagca      600

agctgaaatc aatgaaaaca acgtcaggga attttgcaat gttattgatt gtaatcaaga      660

aaatagttgt gcaagaactg atgcgatttt taccccttac cccggattta aaagtcacgt      720

aaaagtttct agagttgtga atacatacgg accacagact agacctgaag gaattccagg      780

gtcaggtcat aaacctaaca gcatgcttcg agactgtggt aatcaggctg tagaagaacg      840

actacaaaat attgaggccc acttgcggtt acagacaggt ggtccagtgc caagagacat      900

ttatcagaga attaaaaaac ttgaggataa aatccttgaa ttggaaggca tctctcctga      960

atattttcag tctgtaagct tttctggaaa aagaagaaaa gttcaaccac ctcaaaacta     1020

ttcactggct gaacttgatg agaaaattag tgccctcaaa caagccctcc tcagaaaatc     1080

aagagaagca gaatccatgg caacccacca ccttccatga aaaactcctc tcatccttgt     1140

cattttactt ttttgtatac atatgtgtaa cttacactgt tattaattca acggatatat     1200

atttatcaat gtagacttct ctgtgaagtc aaggtttatt ttcacatgag tccagcttgc     1260

agcaagtaat cttcaaatat tccagtaagt tttgaaataa tgaatgcatt gaaaatagca     1320

ttgttggaat ttattccctt ctgttttaaa ggaggtattt tggaaattga aaaacttaat     1380

ttacaagtgc tggtacatct tttttctttt gtggaccaca ggaaggaaga tttattttga     1440

tattgatact ttaaaaggac tttatatttg taacattgat gttaaccagt ttattagttt     1500

aaatcagtac tttgcatata ataagcattc aacaaaaatt tattgactga aatgaatttt     1560

aaatgcatgt gtatgaactt gtttttctta atctttaaga tgtcagtatt catgtaaata     1620

aacaatagat ccagctttat cccttaaaaa aaaaaaaa                             1658


<210>  1291
<211>  6540
<212>  DNA
<213>  homo sapiens

<400>  1291
cggcccagcc gagccgggct gcttgtctgg ccggcggagg ctgagcgcga ccctagcaag       60

ccgcggcgcc cgccgaccag ggacaagagc gactcctggg accccactct gccccgcgcc      120

gccgcctcct cccctgttgt cgcggggacg ctcaggcccg cgccgcccgg gccacgattc      180

tcctcctctt tctcccggag gggaaggaac ggagaaagcc gagcggcggc tccgggagag      240

agcgagccga ggcccctgcc cccgaggctc ggggcaggag gaggaggagg aggaggaggc      300

ggaggcggag ggaagtgcgc gtcactctcg ggaggagagt atttcacctc caggcagagg      360

ctgcggctgc cagttgagta cgagcggcag ctgcgggcgc cggcaatcga gtggcttcct      420

ggccatggag aggagatctg gacccgagga cgccagggac tcctctccgt ctccctggac      480

cgctgtgtag gcacctgagt taacggacgc taagcggggt aggggaagta acagtgtatc      540

atgtatgcca ctgattccag gggacactcc cctgctttcc tccaacctca gaatggaaat      600

agtcgtcacc catctggcta tgttccaggg aaggttgtcc cattgcgtcc ccctcctcct      660

ccaaagagtc aagcttcagc caaatttacc tccatcagac gagaagaccg ggcaaccttc      720

gcattctcac ctgaagaaca gcaagcccag agagaaagtc aaaagcaaaa gagacacaaa      780

aatactttca tttgttttgc tattactagt ttctcatttt ttattgcact tgcaatcatt      840

ttaggaatat cctcaaaata tgctccagat gaaaattgcc cagatcaaaa tcctcgtctc      900

aggaattggg atccaggaca agattctgca aagcaagttg ttatcaagga gggagatatg      960

ctccgtctga cctcagacgc caccgtgcat tctatagtca ttcaggatgg aggactgctt     1020

gtatttgggg acaataaaga tggatccaga aatattactt tgaggactca ttacatcctg     1080

atccaggatg gtggggcgct tcatattgga gcagaaaaat gccgctataa atccaaagcg     1140

acaattacct tgtatggcaa gtcagatgaa ggtgaaagta tgccaacatt tggcaaaaag     1200

tttattggtg tggaagctgg cgggacactg gagttacatg gggcacggaa ggcatcgtgg     1260

acgttgttgg caaggaccct gaattcctca ggcttgccct ttgggtccta tacctttgaa     1320

aaggactttt cccggggcct caatgtgagg gtcattgacc aagacacggc caaaattttg     1380

gaaagtgaga gatttgatac ccatgaatac cgcaatgaga gcaggcggct tcaggagttt     1440

ctgagattcc aggatccagg tcggattgtt gccatagctg tcggggattc agccgctaaa     1500

agtctcttac aaggaaccat ccagatgatc caggaacggt tgggaagtga actgatccaa     1560

ggactgggct acaggcaagc ttgggcttta gttggtgtca ttgatggtgg aagcacttct     1620

tgcaatgaat ccgtgagaaa ctatgaaaat catagcagtg gcgggaaggc tcttgcccaa     1680

agagaatttt atactgtgga tggccagaag ttctctgtga cagcttatag tgaatggatt     1740

gaaggcgttt ctctttcagg attccgggta gaggttgtag atggagtgaa gctaaatttg     1800

ctagatgatg ttagtagttg gaaacctgga gaccagattg tggtcgcaag cacagactat     1860

tccatgtacc aagcagagga gttcactctt cttccctgtt ctgaatgcag ccattttcag     1920

gtcaaagtca aagaaacccc tcagttcctg cacatgggtg agatcataga cggtgtagac     1980

atgagagctg aggttggaat tcttacccgg aatattgtga tccaaggaga agtggaggac     2040

tcatgctacg cagaaaatca gtgccaattt tttgattatg atacctttgg gggacacatt     2100

atgataatga aaaattttac ttcagtccat ctttcttatg tggaattgaa acacatgggt     2160

cagcagcaga tggggcgata ccctgttcat tttcacctgt gtggtgacgt ggattataaa     2220

ggaggataca gacatgcaac atttgtggac ggcctgtcta ttcatcacag cttctcaagg     2280

tgcatcactg tgcatgggac aaatggcttg ctaataaaag acaccattgg gtttgacaca     2340

ctaggtcatt gtttcttttt ggaagatggt attgaacaga ggaatacttt gttccacaat     2400

ctgggactcc tcaccaagcc gggtactctc ctgcccaccg ataggaacaa ctccatgtgt     2460

accaccatgc gagataaagt gtttggaaat tacattcctg tgcctgctac tgactgtatg     2520

gctgtttcaa ctttctggat tgctcatccc aacaataatc tgattaataa tgcagctgca     2580

ggctcacagg atgctggaat atggtattta ttccacaagg aaccaactgg ggaatccagt     2640

ggattgcagc tcttggcaaa accagaactc actccattgg gtatatttta taacaacagg     2700

gtccattcaa attttaaggc tggcttattt attgacaaag gtgtcaaaac aaccaactct     2760

agtgctgctg acccaaggga atacctctgt ttggacaata gtgcaagatt tcgacctcat     2820

caggatgcaa accccgaaaa accacgtgtt gctgctctaa ttgacaggct cattgctttt     2880

aaaaataatg ataatggagc ttgggtcaga ggaggagata ttatcgttca aaattcagca     2940

tttgcagata atggaatagg actgaccttt gccagtgatg gaagcttccc aagtgatgaa     3000

ggttccagcc aagaggtatc tgaatctctc tttgttgggg agagcaggaa ttacggcttt     3060

cagggtggtc agaacaagta tgtaggcact ggaggaatag accagaagcc tcgaacatta     3120

cccaggaaca ggacgttccc aattagaggc tttcagattt atgatgggcc cattcatctc     3180

acaaggagca ctttcaaaaa atatgtgcca actccagata ggtacagcag tgcaattggc     3240

ttcctcatga agaattcctg gcagataacc cccaggaata atatctccct cgtgaagttt     3300

ggtccacatg tctctctgaa tgtctttttt ggaaagcctg gtccctggtt tgaagattgt     3360

gagatggatg gtgataagaa ctccatattc catgacattg atggctctgt gacaggatac     3420

aaggatgctt atgtgggaag aatggacaac tacctgatcc gccatccaag ctgtgtaaat     3480

gtgtctaagt ggaatgcagt gatctgcagt gggacctatg cacaggtcta tgtacagaca     3540

tggagcactc agaatctttc tatgaccatt acacgagatg agtatccgtc caaccctatg     3600

gtgctccgag gtattaatca gaaggctgcc tttccacagt accagcctgt cgtcatgctg     3660

gagaagggtt ataccatcca ctggaatggg ccggcaccac ggactacatt tctatacctc     3720

gtcaacttca acaagaatga ctggattcga gttggccttt gctatccatc aaacacaagt     3780

tttcaagtta cctttggcta tttgcagcgg cagaatggct cattatccaa aatcgaagaa     3840

tatgagcctg tgcattcact ggaagaactg caaagaaagc aatccgagag gaaattctat     3900

tttgactcca gcacggggtt actgtttttg tatctcaaag ccaaaagcca caggcatggc     3960

cacagttact gttcatctca gggatgtgaa agagtcaaga tccaagcagc cacagactca     4020

aaggacatca gtaactgcat ggccaaagca tacccacagt actacagaaa gccgtcagtg     4080

gtcaagcgga tgccggccat gctcactgga ctctgtcaag gctgtggcac tcggcaggtg     4140

gtgtttacta gtgatcctca taaaagttac ctccctgtgc aattccagtc acctgataaa     4200

gcagaaaccc agcgtggaga cccgtctgtt atttctgtca atggcactga ctttaccttc     4260

cgaagtgcag gcgtcctcct ccttgttgtg gatccgtgca gcgttccatt ccgcttgacg     4320

gaaaaaacgg tttttcctct tgctgatgtc agtcgcattg aagagtattt aaaaacaggc     4380

atccctccaa ggtccattgt tctgttgagc acaagaggag aaataaagca gttaaacatt     4440

tcacacttac tagtacctct gggattagcc aaaccagctc atctttatga caaagggagt     4500

accatatttt tgggattcag tggaaacttt aaaccatcat ggactaagct atttaccagt     4560

cctgctggac agggccttgg ggtgcttgaa caattcatac ctttgcagct ggacgaatat     4620

ggttgtccca gagccaccac tgtccgcaga agagacctgg aactgctaaa gcaagcttca     4680

aaagcacatt agagactaac tgtaacttaa gtgctggggg aaaaaaaatg tgaactaact     4740

tatttaattt atggcatttt aaaatgacac tgttaaccca acggaaccat tttccagttt     4800

gatacagaat ggggagaaaa gaaagcgttt gaaattattg cttggatacc agcttcatgc     4860

accttctagt tgtacaaaat gttaaagacg ttgtttgtat ttgtaaggct ggtgtattca     4920

gagagcagat ctcttattcc tcactttcca cccccgtatt ttgtaatgac catgagcaat     4980

gtttttactt tttgtataat ggggtggggt ggagtggggg cttctgagag tcagcctgag     5040

gtctttagag gaccagctat tgtagcacct tggatacttg aagtttaatg ctcagttggg     5100

tcgggtggca gttgacttgg tggctggcat gttcagcagt gcctggggcc ctgtttctgg     5160

gcagcctttg aggattttct atgatattga atgacagttt taagtggcaa ctcaggccca     5220

gctcatgccc ttttttgcct ggacatgtgc tatttttatt cacttatata tcaattactt     5280

gtaagggtta aactttcaaa caggaagtat attgggacaa aagggctctt ggggattaga     5340

tatcccttta atctgtgacc attgggcaaa aaattttcct gcagcaaaag tctgaggctg     5400

ttgggaccat ttttgcagct ttaatcctta gcctcttttg actgtatatt tgtgtttaaa     5460

atgcagagct caactgaata tttccttttt tgttttgttt tgttttgttt taagaagtag     5520

gttgttttcc tgaaccgtaa acttgtatca ttttaacttg cacaaaggaa gtctgttctt     5580

ggtattgctc ttgcacttgg gttttttgtt attgttttgt gtggattttt taaagctttt     5640

ctgttcaccc tcctgccagg aaaatcccag aaagcttaat gataccccaa aatgattaca     5700

cccagggagg aaaaaaagga gcgctttcta gggtcagaat cgtggagaga atactcagaa     5760

atgaacctct ttaaagcctt gcaggaatga gtcactctta cttaatgaaa tgttaaagcc     5820

aattaaaaag catgctgtga tgcccagctt ccctttccac agggtgcatg cgtctcctgc     5880

tggtgaatca catgcggcaa gaggcaactg gctccacagc ctgggatgct gccgtaccaa     5940

gaggaaagaa gcagcaaaat gcctttacgt tgttctaaac ccccgacgca taaagtgtag     6000

aggagggatg gccaagggtg ggtggtagaa agtgtgttca ggctgacact ggcaatgagt     6060

acagataatt tcactttcct cttctagggg caaaggctga tggcctctac ctttgtatcc     6120

aggagaaact gcagagcagc cctgtgactt tacaaaatat gctacctcaa agtgctaccg     6180

ataaaccttt ctaattgtaa gtgcccttac taagggcaca tgtcttaatc aaagttagtt     6240

ttttgttttc tggtttgttt tttttttttg tatattgatg aatgagatct tacctattaa     6300

atatattatt ggattatggt tcctgaaggt cattagagtg tgtgtgtgtg tgtgtgtgtg     6360

tgtgtgtgtt ttatgactta aatatcttta cgtgtgtttt ttagagcttg gttctttaaa     6420

gatttggaga agatatgtaa attaccaagg cacttggttt ttctgtttta tatactaata     6480

atcagggcct aagttaaata aaaatatgtg tgcatgtatt ttaaaaaaaa aaaaaaaaaa     6540


<210>  1292
<211>  1927
<212>  DNA
<213>  homo sapiens

<400>  1292
acgccggcgc tcccaggccg cgcttcctgc gtccccaacc cggtccctga gagggcagtg       60

cgccctctcc accactgcgt tccctcggct aagaatcccc cgaaccccag ccccgcgatc      120

gcggcgccca ccgaggaggc cgcccgggtg gggcgcgggg gtcgcgaagc ccgcagtccc      180

ggaccgccca gccgagacgg agccggaccc gccgcctccc gggcccttcc accgcagcca      240

tccgcacggg aggcctcgcg attgctcgga accatcccgc aggagttcag ctgatatttt      300

ctagtgtggg gcgagagatt ttgtggagcg catttaaggg gtttttgttg tgactgctgc      360

cttgtatata tttattttct ttcttggaac tgggcctcgc cctcctccca ctgacatgat      420

ggcccagtcc aaggccaatg gctcgcacta tgcgctgacc gccatcggcc tggggatgct      480

ggtccttggg gtgatcatgg ccatgtggaa cctggtaccc ggcttcagcg cggccgagaa      540

gccaacagct cagggcagca acaagaccga ggtgggtggc ggcatcctca agagcaagac      600

cttctctgtg gcctacgtgc tggtcggggc cggggtgatg ctgctgctgc tttctatctg      660

cctgagtatc agggataaga ggaagcagcg gcagggcgag gacctggccc atgtccagca      720

cccgacaggc gctgggcctc acgcccagga ggaagacagc caggaggaag aagaggagga      780

tgaggaggct gcctcaaggt actatgttcc cagctacgag gaagtgatga acacaaacta      840

ctcagaagca aggggagagg agcagaaccc gaggttgagc atctctctcc cgtcctatga      900

gtcactgacg gggctcgacg agaccacccc cacatccacc agggctgacg tggaggccag      960

ccctgggaac ccccctgaca ggcagaactc taagttggcc aaacgactga aaccgctgaa     1020

agttcgaagg attaaatctg aaaagcttca cctcaaagac tttaggatca acctcccaga     1080

caaaaacgtc cctcctccct cgatagagcc tttgactcct ccaccgcagt atgatgaagt     1140

ccaggagaag gcccccgaca cccggccgcc cgactgaatg gccccacttg agccacgctc     1200

cctcctgtct ctcacacctt tcacccccaa gactctaaca aagccacatg agccacagtt     1260

gagaagcgga ggggccagct gtgcatggag ccatttggat ggcggcgggc ggggggggat     1320

tctctgtatc aggagtgact ttgttgcccc acacagcctc ctgctgcagg tgctttggaa     1380

agagatgctg ccttggagct ggtgaatctg tggaccacat tcaagggtgt ggcacaggca     1440

tcttcccatc cttttcactc cgaatcgctg gcgacacatt ctcctttcca gctaggaaag     1500

ggttcctcgc ggctggttta gattgtggtt gtttgttttg cttctactaa gactgttttg     1560

tttcaaaaag gaaacaagtt ttgtgtttgc tgtctacgct ggagtcctga actgtgggta     1620

gaaaacacga cctggctttg tagaaaggac acagggctgt tttatgaact aagcggtgag     1680

gctcaggtgg cggctctcgc agagcccctg atgctgttgt tctttgaggg cttaaggcct     1740

gatgaacgta ggcacgtgat gcataatagt cttcaatggt acacttaact agtctcttct     1800

gtgtaacagc aaaaaaaaaa aaaaaaagaa gaagaaagaa aactgtagga aatgttcttt     1860

ttgaaatgcc atgcaatgga gctttttgta ataaaatatt ttatatgtag taaaaaaaaa     1920

aaaaaaa                                                               1927


<210>  1293
<211>  2031
<212>  DNA
<213>  homo sapiens

<400>  1293
cagctgccta tcggcttctc agtgtttgaa cttcaaaggg ctggacgctc acccaagaag       60

gggaccccgg cctgacctct ctcggaattc aaaaaaatct aaggctcaga gagggaatgg      120

gagctggctc ttccctctgt gtttagcatc cacgtttttt ggcggtctgg ctgaaaccag      180

cccaccctag ttcgggcgcc agagcaacgc agttccgagg gcagatctcc aaggggcgga      240

ggcagagccg cgggtggatc tttaactcaa gactagcatg aagagttgcc ttctggcctg      300

ccctgagtct cctcaaataa caacaggccc ttccaccgca gccatccgca cgggaggcct      360

cgcgattgct cggaaccatc ccgcaggagt tcagctgata ttttctagtg tggggcgaga      420

gattttgtgg agcgcattta aggggttttt gttgtgactg ctgccttgta tatatttatt      480

ttctttcttg gaactgggcc tcgccctcct cccactgaca tgatggccca gtccaaggcc      540

aatggctcgc actatgcgct gaccgccatc ggcctgggga tgctggtcct tggggtgatc      600

atggccatgt ggaacctggt acccggcttc agcgcggccg agaagccaac agctcagggc      660

agcaacaaga ccgaggtggg tggcggcatc ctcaagagca agaccttctc tgtggcctac      720

gtgctggtcg gggccggggt gatgctgctg ctgctttcta tctgcctgag tatcagggat      780

aagaggaagc agcggcaggg cgaggacctg gcccatgtcc agcacccgac aggcgctggg      840

cctcacgccc aggaggaaga cagccaggag gaagaagagg aggatgagga ggctgcctca      900

aggtactatg ttcccagcta cgaggaagtg atgaacacaa actactcaga agcaagggga      960

gaggagcaga acccgaggtt gagcatctct ctcccgtcct atgagtcact gacggggctc     1020

gacgagacca cccccacatc caccagggct gacgtggagg ccagccctgg gaacccccct     1080

gacaggcaga actctaagtt ggccaaacga ctgaaaccgc tgaaagttcg aaggattaaa     1140

tctgaaaagc ttcacctcaa agactttagg atcaacctcc cagacaaaaa cgtccctcct     1200

ccctcgatag agcctttgac tcctccaccg cagtatgatg aagtccagga gaaggccccc     1260

gacacccggc cgcccgactg aatggcccca cttgagccac gctccctcct gtctctcaca     1320

cctttcaccc ccaagactct aacaaagcca catgagccac agttgagaag cggaggggcc     1380

agctgtgcat ggagccattt ggatggcggc gggcgggggg ggattctctg tatcaggagt     1440

gactttgttg ccccacacag cctcctgctg caggtgcttt ggaaagagat gctgccttgg     1500

agctggtgaa tctgtggacc acattcaagg gtgtggcaca ggcatcttcc catccttttc     1560

actccgaatc gctggcgaca cattctcctt tccagctagg aaagggttcc tcgcggctgg     1620

tttagattgt ggttgtttgt tttgcttcta ctaagactgt tttgtttcaa aaaggaaaca     1680

agttttgtgt ttgctgtcta cgctggagtc ctgaactgtg ggtagaaaac acgacctggc     1740

tttgtagaaa ggacacaggg ctgttttatg aactaagcgg tgaggctcag gtggcggctc     1800

tcgcagagcc cctgatgctg ttgttctttg agggcttaag gcctgatgaa cgtaggcacg     1860

tgatgcataa tagtcttcaa tggtacactt aactagtctc ttctgtgtaa cagcaaaaaa     1920

aaaaaaaaaa agaagaagaa agaaaactgt aggaaatgtt ctttttgaaa tgccatgcaa     1980

tggagctttt tgtaataaaa tattttatat gtagtaaaaa aaaaaaaaaa a              2031


<210>  1294
<211>  6021
<212>  DNA
<213>  homo sapiens

<400>  1294
cggcgaacag acgttctttc tcctccatgc agttacacaa aaggagggct acggaaacta       60

aaagtttcgg ggcctctggc tcggtgcgtg gagaaaagag aaaacctgga gacgggatat      120

gaagatcaat gatgcagact gatggttttg atgaagctgg gcatttataa ctagattcat      180

taaggaatac aaagaaaata cttaaaggga tcaataatgg tgtcttctgg ttgcagaatg      240

cgaagtctgt ggtttatcat tgtaatcagc ttcttaccaa atacagaagg tttcagcaga      300

gcagctttac catttgggct ggtgaggcga gaattatcct gtgaaggtta ttctatagat      360

ctgcgatgcc cgggcagtga tgtcatcatg attgagagcg ctaactatgg tcggacggat      420

gacaagattt gtgatgctga cccatttcag atggagaata cagactgcta cctccccgat      480

gccttcaaaa ttatgactca aaggtgcaac aatcgaacac agtgtatagt agttactggg      540

tcagatgtgt ttcctgatcc atgtcctgga acatacaaat accttgaagt ccaatatgaa      600

tgtgtccctt acatttttgt gtgtcctggg accttgaaag caattgtgga ctcaccatgt      660

atatatgaag ctgaacaaaa ggcgggtgct tggtgcaagg accctcttca ggctgcagat      720

aaaatttatt tcatgccctg gactccctat cgtaccgata ctttaataga atatgcttct      780

ttagaagatt tccaaaatag tcgccaaaca acaacatata aacttccaaa tcgagtagat      840

ggtactggat ttgtggtgta tgatggtgct gtcttcttta acaaagaaag aacgaggaat      900

attgtgaaat ttgacttgag gactagaatt aagagtggcg aggccataat taactatgcc      960

aactaccatg atacctcacc atacagatgg ggaggaaaga ctgatatcga cctagcagtt     1020

gatgaaaatg gtttatgggt catttacgcc actgaacaga acaatggaat gatagttatt     1080

agccagctga atccatacac tcttcgattt gaagcaacgt gggagactgt atacgacaaa     1140

cgtgccgcat caaatgcttt tatgatatgc ggagtcctct atgtggttag gtcagtttat     1200

caagacaatg aaagtgaaac aggcaagaac tcaattgatt acatttataa tacccgatta     1260

aaccgaggag aatatgtaga tgttcccttc cccaaccagt atcagtatat tgctgcagtg     1320

gattacaatc caagagataa ccaactttac gtgtggaaca ataacttcat tttacgatat     1380

tctctggagt ttggtccacc tgatcctgcc caagtgccta ccacagctgt gacaataact     1440

tcttcagctg agctgttcaa aaccataata tcaaccacaa gcactacttc acagaaaggc     1500

cccatgagca caactgtagc tggatcacag gaaggaagca aagggacaaa accacctcca     1560

gcagtttcta caaccaaaat tccacctata acaaatattt ttcccctgcc agagagattc     1620

tgtgaagcat tagactccaa ggggataaag tggcctcaga cacaaagggg aatgatggtt     1680

gaacgaccat gccctaaggg aacaagagga actgcctcat atctctgcat gatttccact     1740

ggaacatgga accctaaggg ccccgatctt agcaactgta cctcacactg ggtgaatcag     1800

ctggctcaga agatcagaag cggagaaaat gctgctagtc ttgccaatga actggctaaa     1860

cataccaaag ggccagtgtt tgctggggat gtaagttctt cagtgagatt gatggagcag     1920

ttggtggaca tccttgatgc acagctgcag gaactgaaac ctagtgaaaa agattcagct     1980

ggacggagtt ataacaaggc aattgttgac acagtggaca accttctgag acccgaagct     2040

ttggaatcat ggaaacatat gaattcttct gaacaagcac atactgcaac aatgttactc     2100

gatacattgg aagaaggagc ttttgtccta gctgacaatc ttttagaacc aacaagggtc     2160

tcaatgccca cagaaaatat tgtcctggaa gttgccgtac tcagtacaga aggacagatc     2220

caagacttta aatttcctct gggcatcaaa ggagcaggca gctcaatcca actgtccgca     2280

aataccgtca aacagaacag caggaatggg cttgcaaagt tggtgttcat catttaccgg     2340

agcctgggac agttccttag tacagaaaat gcaaccatta aactgggtgc tgattttatt     2400

ggtcgtaata gcaccattgc agtgaactct cacgtcattt cagtttcaat caataaagag     2460

tccagccgag tatacctgac tgatcctgtg ctttttaccc tgccacacat tgatcctgac     2520

aattatttca atgcaaactg ctccttctgg aactactcag agagaactat gatgggatat     2580

tggtctaccc agggctgcaa gctggttgac actaataaaa ctcgaacaac gtgtgcatgc     2640

agccacctaa ccaattttgc aattctcatg gcccacaggg aaattgcata taaagatggc     2700

gttcatgaat tacttcttac agtcatcacc tgggtgggaa ttgtcatttc ccttgtttgc     2760

ctggctatct gcatcttcac cttctgcttt ttccgtggcc tacagagtga ccgaaatact     2820

attcacaaga acctttgtat caaccttttc attgctgaat ttattttcct aataggcatt     2880

gataagacaa aatatgcgat tgcatgccca atatttgcag gacttctaca ctttttcttt     2940

ttggcagctt ttgcttggat gtgcctagaa ggtgtgcagc tctacctaat gttagttgaa     3000

gtttttgaaa gtgaatattc aaggaaaaaa tattactatg ttgctggtta cttgtttcct     3060

gccacagtgg ttggagtttc agctgctatt gactataaga gctatggaac agaaaaagct     3120

tgctggcttc atgttgataa ctactttata tggagcttca ttggacctgt taccttcatt     3180

attctgctaa atattatctt cttggtgatc acattgtgca aaatggtgaa gcattcaaac     3240

actttgaaac cagattctag caggttggaa aacattaagt cttgggtgct tggcgctttc     3300

gctcttctgt gtcttcttgg cctcacctgg tcctttgggt tgctttttat taatgaggag     3360

actattgtga tggcatatct cttcactata tttaatgctt tccagggagt gttcattttc     3420

atctttcact gtgctctcca aaagaaagta cgaaaagaat atggcaagtg cttcagacac     3480

tcatactgct gtggaggcct cccaactgag agtccccaca gttcagtgaa ggcatcaacc     3540

accagaacca gtgctcgcta ttcctctggc acacagagtc gtataagaag aatgtggaat     3600

gatactgtga gaaaacaatc agaatcttct tttatctcag gtgacatcaa tagcacttca     3660

acacttaatc aaggacattc actgaacaat gccagggata caagtgccat ggatactcta     3720

ccgctaaatg gtaattttaa caacagctac tcgctgcaca agggtgacta taatgacagc     3780

gtgcaagttg tggactgtgg actaagtctg aatgatactg cttttgagaa aatgatcatt     3840

tcagaattag tgcacaacaa cttacggggc agcagcaaga ctcacaacct cgagctcacg     3900

ctaccagtca aacctgtgat tggaggtagc agcagtgaag atgatgctat tgtggcagat     3960

gcttcatctt taatgcacag cgacaaccca gggctggagc tccatcacaa agaactcgag     4020

gcaccactta ttcctcagcg gactcactcc cttctgtacc aaccccagaa gaaagtgaag     4080

tccgagggaa ctgacagcta tgtctcccaa ctgacagcag aggctgaaga tcacctacag     4140

tcccccaaca gagactctct ttatacaagc atgcccaatc ttagagactc tccctatccg     4200

gagagcagcc ctgacatgga agaagacctc tctccctcca ggaggagtga gaatgaggac     4260

atttactata aaagcatgcc aaatcttgga gctggccatc agcttcagat gtgctaccag     4320

atcagcaggg gcaatagtga tggttatata atccccatta acaaagaagg gtgtattcca     4380

gaaggagatg ttagagaagg acaaatgcag ctggttacaa gtctttaatc atacagctaa     4440

ggaattccaa gggccacatg cgagtattaa taaataaaga caccattggc ctgacgcagc     4500

tccctcaaac tctgcttgaa gagatgactc ttgacctgtg gttctctggt gtaaaaaaga     4560

tgactgaacc ttgcagttct gtgaattttt ataaaacata caaaaacttt gtatatacac     4620

agagtatact aaagtgaatt atttgttaca aagaaaagag atgccagcca ggtattttaa     4680

gattctgctg ctgtttagag aaattgtgaa acaagcaaaa caaaactttc cagccatttt     4740

actgcagcag tctgtgaact aaatttgtaa atatggctgc accatttttg taggcctgca     4800

ttgtattata tacaagacgt aggctttaaa atcctgtggg acaaatttac tgtaccttac     4860

tattcctgac aagacttgga aaagcaggag agatattctg catcagtttg cagttcactg     4920

caaatctttt acattaaggc aaagattgaa aacatgctta accactagca atcaagccac     4980

aggccttatt tcatatgttt cctcaactgt acaatgaact attctcatga aaaatggcta     5040

aagaaattat attttgttct attgctaggg taaaataaat acatttgtgt ccaactgaaa     5100

tataattgtc attaaaataa ttttaaagag tgaagaaaat attgtgaaaa gctcttggtt     5160

gcacatgtta tgaaatgttt tttcttacac tttgtcatgg taagttctac tcattttcac     5220

ttcttttcca ctgtatacag tgttctgctt tgacaaagtt agtctttatt acttacattt     5280

aaatttctta ttgccaaaag aacgtgtttt atggggagaa acaaactctt tgaagccagt     5340

tatgtcatgc cttgcacaaa agtgatgaaa tctagaaaag attgtgtgtc acccctgttt     5400

attcttgaac agagggcaaa gagggcactg ggcacttctc acaaactttc tagtgaacaa     5460

aaggtgccta ttctttttta aaaaaataaa ataaaacata aatattactc ttccatattc     5520

cttctgccta tatttagtaa ttaatttatt ttatgataaa gttctaatga aatgtaaatt     5580

gtttcagcaa aattctgctt ttttttcatc cctttgtgta aacctgttaa taatgagccc     5640

atcactaata tccagtgtaa agtttaacac ggtttgacag taaataaatg tgaatttttt     5700

caagtagtta acatgtgaac ttttatgtat gatacataat tggctttaac atgttggtcc     5760

attcccacct tggtttaagt aacgtcatac caaagtccat ggatatatga aaggatacaa     5820

ttaagttgcc tgtttgttct ttatgctgaa aggaatatat gtcttccaat tgcccactac     5880

atatgcacaa aatctgctgg ataagtttta agagggatat attctgaaag catttttgtt     5940

tgttgcattg taccaggact aaaaaaagaa ggattggaag ttctgccatc aaatttgggt     6000

atcataaaaa gtttttaact g                                               6021


<210>  1295
<211>  15735
<212>  DNA
<213>  homo sapiens

<400>  1295
ggtctaaagg gctttatgca ctgtctggag ggtggggact ggcgcgggta gaaaacggga       60

tgcctcgggc gtgggggcag gcttttggcc actaggagct ggcggaggtg cagacctaaa      120

ggagcgttcg ctagcagagg cgctgccggt gcggtgtgct acgcgcgccc acctcccggg      180

gaaggaacgg cgaggccggg gaccgtcgcg gagatggatc gcgggccggc agcagtggcg      240

tgcacgctgc tcctggctct cgtcgcctgc ctagcgccgg ccagtggcca agaatgtgac      300

agtgcgcatt ttcgctgtgg aagtgggcat tgcatccctg cagactggag gtgtgatggg      360

accaaagact gttcagatga cgcggatgaa attggctgcg ctgttgtgac ctgccagcag      420

ggctatttca agtgccagag tgagggacaa tgcatcccca actcctgggt gtgtgaccaa      480

gatcaagact gtgatgatgg ctcagatgaa cgtcaagatt gctcacaaag tacatgctca      540

agtcatcaga taacatgctc caatggtcag tgtatcccaa gtgaatacag gtgcgaccac      600

gtcagagact gccccgatgg agctgatgag aatgactgcc agtacccaac atgtgagcag      660

cttacttgtg acaatggggc ctgctataac accagtcaga agtgtgattg gaaagttgat      720

tgcagggact cctcagatga aatcaactgc actgagatat gcttgcacaa tgagttttca      780

tgtggcaatg gagagtgtat ccctcgtgct tatgtctgtg accatgacaa tgattgccaa      840

gacggcagtg acgaacatgc ttgcaactat ccgacctgcg gtggttacca gttcacttgc      900

cccagtggcc gatgcattta tcaaaactgg gtttgtgatg gagaagatga ctgtaaagat      960

aatggagatg aagatggatg tgaaagcggt cctcatgatg ttcataaatg ttccccaaga     1020

gaatggtctt gcccagagtc gggacgatgc atctccattt ataaagtttg tgatgggatt     1080

ttagattgcc caggaagaga agatgaaaac aacactagta ccggaaaata ctgtagtatg     1140

actctgtgct ctgccttgaa ctgccagtac cagtgccatg agacgccgta tggaggagcg     1200

tgtttttgtc ccccaggtta tatcatcaac cacaatgaca gccgtacctg tgttgagttt     1260

gatgattgcc agatatgggg aatttgtgac cagaagtgtg aaagccgacc tggccgtcac     1320

ctgtgccact gtgaagaagg gtatatcttg gagcgtggac agtattgcaa agctaatgat     1380

tcctttggcg aggcctccat tatcttctcc aatggtcggg atttgttaat tggtgatatt     1440

catggaagga gcttccggat cctagtggag tctcagaatc gtggagtggc cgtgggtgtg     1500

gctttccact atcacctgca aagagttttt tggacagaca ccgtgcaaaa taaggttttt     1560

tcagttgaca ttaatggttt aaatatccaa gaggttctca atgtttctgt tgaaacccca     1620

gagaacctgg ctgtggactg ggttaataat aaaatctatc tagtggaaac caaggtcaac     1680

cgcatagata tggtaaattt ggatggaagc tatcgggtta cccttataac tgaaaacttg     1740

gggcatccta gaggaattgc cgtggaccca actgttggtt atttattttt ctcagattgg     1800

gagagccttt ctggggaacc taagctggaa agggcattca tggatggcag caaccgtaaa     1860

gacttggtga aaacaaagct gggatggcct gctggggtaa ctctggatat gatatcgaag     1920

cgtgtttact gggttgactc tcggtttgat tacattgaaa ctgtaactta tgatggaatt     1980

caaaggaaga ctgtagttca tggaggctcc ctcattcctc atccctttgg agtaagctta     2040

tttgaaggtc aggtgttctt tacagattgg acaaagatgg ccgtgctgaa ggcaaacaag     2100

ttcacagaga ccaacccaca agtgtactac caggcttccc tgaggcccta tggagtgact     2160

gtttaccatt ccctcagaca gccctatgct accaatccgt gtaaagataa caatgggggc     2220

tgtgagcagg tctgtgtcct cagccacaga acagataatg atggtttggg tttccgttgc     2280

aagtgcacat tcggcttcca actggataca gatgagcgcc actgcattgc tgttcagaat     2340

ttcctcattt tttcatccca agttgctatt cgtgggatcc cgttcacctt gtctacccag     2400

gaagatgtca tggttccagt ttcggggaat ccttctttct ttgtcgggat tgattttgac     2460

gcccaggaca gcactatctt tttttcagat atgtcaaaac acatgatttt taagcaaaag     2520

attgatggca caggaagaga aattctcgca gctaacaggg tggaaaatgt tgaaagtttg     2580

gcttttgatt ggatttcaaa gaatctctat tggacagact ctcattacaa gagtatcagt     2640

gtcatgaggc tagctgataa aacgagacgc acagtagttc agtatttaaa taacccacgg     2700

tcggtggtag ttcatccttt tgccgggtat ctattcttca ctgattggtt ccgtcctgct     2760

aaaattatga gagcatggag tgacggatct cacctcttgc ctgtaataaa cactactctt     2820

ggatggccca atggcttggc catcgattgg gctgcttcac gattgtactg ggtagatgcc     2880

tattttgata aaattgagca cagcaccttt gatggtttag acagaagaag actgggccat     2940

atagagcaga tgacacatcc gtttggactt gccatctttg gagagcattt attttttact     3000

gactggagac tgggtgccat tattcgagtc aggaaagcag atggtggaga aatgacagtt     3060

atccgaagtg gcattgctta catactgcat ttgaaatcgt atgatgtcaa catccagact     3120

ggttctaacg cctgtaatca acccacgcat cctaacggtg actgcagcca cttctgcttc     3180

ccggtgccaa atttccagcg agtgtgtggg tgcccttatg gaatgaggct ggcttccaat     3240

cacttgacat gcgaggggga cccaaccaat gaaccaccca cagagcagtg tggcttattt     3300

tccttcccct gtaaaaatgg cagatgtgtg cccaattact atctctgtga tggagtcgat     3360

gattgtcatg ataacagtga tgagcaacta tgtggcacac ttaataatac ctgttcatct     3420

tcggcgttca cctgtggcca tggggagtgc attcctgcac actggcgctg tgacaaacgc     3480

aacgactgtg tggatggcag tgatgagcac aactgcccca cccacgcacc tgcttcctgc     3540

cttgacaccc aatacacctg tgataatcac cagtgtatct caaagaactg ggtctgtgac     3600

acagacaatg attgtgggga tggatctgat gaaaagaact gcaattcgac agagacatgc     3660

caacctagtc agtttaattg ccccaatcat cgatgtattg acctatcgtt tgtctgtgat     3720

ggtgacaagg attgtgttga tggatctgat gaggttggtt gtgtattaaa ctgtactgct     3780

tctcaattca agtgtgccag tggggataaa tgtattggcg tcacaaatcg ttgtgatggt     3840

gtttttgatt gcagtgacaa ctcggatgaa gcaggctgtc caaccaggcc tcctggtatg     3900

tgccactcag atgaatttca gtgccaagaa gatggtatct gcatcccgaa cttctgggaa     3960

tgtgatgggc atccagactg cctctatgga tctgatgagc acaatgcctg tgtccccaag     4020

acttgccctt catcatattt ccactgtgac aacggaaact gcatccacag ggcatggctc     4080

tgtgatcggg acaatgactg cggggatatg agtgatgaga aggactgccc tactcagccc     4140

tttcgctgtc ctagttggca atggcagtgt cttggccata acatctgtgt gaatctgagt     4200

gtagtgtgtg atggcatctt tgactgcccc aatgggacag atgagtcccc actttgcaat     4260

gggaacagct gctcagattt caatggtggt tgtactcacg agtgtgttca agagcccttt     4320

ggggctaaat gcctatgtcc attgggattc ttacttgcca atgattctaa gacctgtgaa     4380

gacatagatg aatgtgatat tctaggctct tgtagccagc actgttacaa tatgagaggt     4440

tctttccggt gctcgtgtga tacaggctac atgttagaaa gtgatgggag gacttgcaaa     4500

gttacagcat ctgagagtct gctgttactt gtggcaagtc agaacaaaat tattgccgac     4560

agtgtcacct cccaggtcca caatatctat tcattggtcg agaatggttc ttacattgta     4620

gctgttgatt ttgattcaat tagtggtcgt atcttttggt ctgatgcaac tcagggtaaa     4680

acctggagtg cgtttcaaaa tggaacggac agaagagtgg tatttgacag tagcatcatc     4740

ttgactgaaa ctattgcaat agattgggta ggtcgtaatc tttactggac agactatgct     4800

ctggaaacaa ttgaagtctc caaaattgat gggagccaca ggactgtgct gattagtaaa     4860

aacctaacaa atccaagagg actagcatta gatcccagaa tgaatgagca tctactgttc     4920

tggtctgact ggggccacca ccctcgcatc gagcgagcca gcatggacgg cagcatgcgc     4980

actgtcattg tccaggacaa gatcttctgg ccctgcggct taactattga ctaccccaac     5040

agactgctct acttcatgga ctcctatctt gattacatgg acttttgtga ttataatgga     5100

caccatcgga gacaggtgat agccagtgat ttgattatac ggcaccccta tgccctaact     5160

ctctttgaag actctgtgta ctggactgac cgtgctactc gtcgggttat gcgagccaac     5220

aagtggcatg gagggaacca gtcagttgta atgtataata ttcaatggcc ccttgggatt     5280

gttgcggttc atccttcgaa acaaccaaat tccgtgaatc catgtgcctt ttcccgctgc     5340

agccatctct gcctgctttc ctcacagggg cctcattttt actcctgtgt ttgtccttca     5400

ggatggagtc tgtctcctga tctcctgaat tgcttgagag atgatcaacc tttcttaata     5460

actgtaaggc aacatataat ttttggaatc tcccttaatc ctgaggtgaa gagcaatgat     5520

gctatggtcc ccatagcagg gatacagaat ggtttagatg ttgaatttga tgatgctgag     5580

caatacatct attgggttga aaatccaggt gaaattcaca gagtgaagac agatggcacc     5640

aacaggacag tatttgcttc tatatctatg gtggggcctt ctatgaacct ggccttagat     5700

tggatttcaa gaaaccttta ttctaccaat cctagaactc agtcaatcga ggttttgaca     5760

ctccacggag atatcagata cagaaaaaca ttgattgcca atgatgggac agctcttgga     5820

gttggctttc caattggcat aactgttgat cctgctcgtg ggaagctgta ctggtcagac     5880

caaggaactg acagtggggt tcctgccaag atcgccagtg ctaacatgga tggcacatct     5940

gtgaaaactc tctttactgg gaacctcgaa cacctggagt gtgtcactct tgacatcgaa     6000

gagcagaaac tctactgggc agtcactgga agaggagtga ttgaaagagg aaacgtggat     6060

ggaacagatc gaatgatcct ggtacaccag ctttcccacc cctggggaat tgcagtccat     6120

gattctttcc tttattatac tgatgaacag tatgaggtca ttgaaagagt tgataaggcc     6180

actggggcca acaaaatagt cttgagagat aatgttccaa atctgagggg tcttcaagtt     6240

tatcacagac gcaatgccgc cgaatcctca aatggctgta gcaacaacat gaatgcctgt     6300

cagcagattt gcctgcctgt accaggagga ttgttttcct gcgcctgtgc cactggattt     6360

aaactcaatc ctgataatcg gtcctgctct ccatataact ctttcattgt tgtttcaatg     6420

ctgtctgcaa tcagaggctt tagcttggaa ttgtcagatc attcagaaac catggtgccg     6480

gtggcaggcc aaggacgaaa cgcactgcat gtggatgtgg atgtgtcctc tggctttatt     6540

tattggtgtg attttagcag ctcagtggca tctgataatg cgatccgtag aattaaacca     6600

gatggatctt ctctgatgaa cattgtgaca catggaatag gagaaaatgg agtccggggt     6660

attgcagtgg attgggtagc aggaaatctt tatttcacca atgcctttgt ttctgaaaca     6720

ctgatagaag ttctgcggat caatactact taccgccgtg ttcttcttaa agtcacagtg     6780

gacatgccta ggcatattgt tgtagatccc aagaacagat acctcttctg ggctgactat     6840

gggcagagac caaagattga gcgttctttc cttgactgta ccaatcgaac agtgcttgtg     6900

tcagagggca ttgtcacacc acggggcttg gcagtggacc gaagtgatgg ctacgtttat     6960

tgggttgatg attctttaga tataattgca aggattcgta tcaatggaga gaactctgaa     7020

gtgattcgtt atggcagtcg ttacccaact ccttatggca tcactgtttt tgaaaattct     7080

atcatatggg tagataggaa tttgaaaaag atcttccaag ccagcaagga accagagaac     7140

acagagccac ccacagtgat aagagacaat atcaactggc taagagatgt gaccatcttt     7200

gacaagcaag tccagccccg gtcaccagca gaggtcaaca acaacccttg cttggaaaac     7260

aatggtgggt gctctcatct ctgctttgct ctgcctggat tgcacacccc aaaatgtgac     7320

tgtgcctttg ggaccctgca aagtgatggc aagaattgtg ccatttcaac agaaaatttc     7380

ctcatctttg ccttgtctaa ttccttgaga agcttacact tggaccctga aaaccatagc     7440

ccacctttcc aaacaataaa tgtggaaaga actgtcatgt ctctagacta tgacagtgta     7500

agtgatagaa tctacttcac acaaaattta gcctctggag ttggacagat ttcctatgcc     7560

accctgtctt cagggatcca tactccaact gtcattgctt caggtatagg gactgctgat     7620

ggcattgcct ttgactggat tactagaaga atttattaca gtgactacct caaccagatg     7680

attaattcca tggctgaaga tgggtctaac cgcactgtga tagcccgcgt tccaaaacca     7740

agagcaattg tgttagatcc ctgccaaggg tacctgtact gggctgactg ggatacacat     7800

gccaaaatcg agagagccac attgggagga aacttccgcg tacccattgt gaacagcagt     7860

ctggtcatgc ccagtgggct gactctggac tatgaagagg accttctcta ctgggtggat     7920

gctagtctgc agaggattga acgcagcact ctgacgggcg tggatcgtga agtcattgtc     7980

aatgcagccg ttcatgcttt tggcttgact ctctatggcc agtatattta ctggactgac     8040

ttgtacacac aaagaattta ccgagctaac aaatatgacg ggtcaggtca gattgcaatg     8100

accacaaatt tgctctccca gcccagggga atcaacactg ttgtgaagaa ccagaaacaa     8160

cagtgtaaca atccttgtga acagtttaat gggggctgca gccatatctg tgcaccaggt     8220

ccaaatggtg ccgagtgcca gtgtccacat gagggcaact ggtatttggc caacaacagg     8280

aagcactgca ttgtggacaa tggtgaacga tgtggtgcat cttccttcac ctgctccaat     8340

gggcgctgca tctcggaaga gtggaagtgt gataatgaca acgactgtgg ggatggcagt     8400

gatgagatgg aaagtgtctg tgcacttcac acctgctcac cgacagcctt cacctgtgcc     8460

aatgggcgat gtgtccaata ctcttaccgc tgtgattact acaatgactg tggtgatggc     8520

agtgatgagg cagggtgcct gttcagggac tgcaatgcca ccacggagtt tatgtgcaat     8580

aacagaaggt gcatacctcg tgagtttatc tgcaatggtg tagacaactg ccatgataat     8640

aacacttcag atgagaaaaa ttgccctgat cgcacttgcc agtctggata cacaaaatgt     8700

cataattcaa atatttgtat tcctcgcgtt tatttgtgtg acggagacaa tgactgtgga     8760

gataacagtg atgaaaaccc tacttattgc accactcaca cgtgcagcag cagtgagttc     8820

caatgcgcat ctgggcgctg tattcctcaa cattggtatt gtgatcaaga aacagattgt     8880

tttgatgcct ctgatgaacc tgcctcttgt ggtcactctg agcgaacatg cctagctgat     8940

gagttcaagt gtgatggtgg gaggtgcatc ccaagcgaat ggatctgtga cggtgataat     9000

gactgtgggg atatgagtga cgaggataaa aggcaccagt gtcagaatca aaactgctcg     9060

gattccgagt ttctctgtgt aaatgacaga cctccggaca ggaggtgcat tccccagtct     9120

tgggtctgtg atggcgatgt ggattgtact gacggctacg atgagaatca gaattgcacc     9180

aggagaactt gctctgaaaa tgaattcacc tgtggttacg gactgtgtat cccaaagata     9240

ttcaggtgtg accggcacaa tgactgtggt gactatagcg acgagagggg ctgcttatac     9300

cagacttgcc aacagaatca gtttacctgt cagaacgggc gctgcattag taaaaccttc     9360

gtctgtgatg aggataatga ctgtggagac ggatctgatg agctgatgca cctgtgccac     9420

accccagaac ccacgtgtcc acctcacgag ttcaagtgtg acaatgggcg ctgcatcgag     9480

atgatgaaac tctgcaacca cctagatgac tgtttggaca acagcgatga gaaaggctgt     9540

ggcattaatg aatgccatga cccttcaatc agtggctgcg atcacaactg cacagacacc     9600

ttaaccagtt tctattgttc ctgtcgtcct ggttacaagc tcatgtctga caagcggact     9660

tgtgttgata ttgatgaatg cacagagatg ccttttgtct gtagccagaa gtgtgagaat     9720

gtaataggct cctacatctg taagtgtgcc ccaggctacc tccgagaacc agatggaaag     9780

acctgccggc aaaacagtaa catcgaaccc tatctcattt ttagcaaccg ttactatttg     9840

agaaatttaa ctatagatgg ctatttttac tccctcatct tggaaggact ggacaatgtt     9900

gtggcattag attttgaccg agtagagaag agattgtatt ggattgatac acagaggcaa     9960

gtcattgaga gaatgtttct gaataagaca aacaaggaga caatcataaa ccacagacta    10020

ccagctgcag aaagtctggc tgtagactgg gtttccagaa agctctactg gttggatgcc    10080

cgcctggatg gcctctttgt ctctgacctc aatggtggac accgccgcat gctggcccag    10140

cactgtgtgg atgccaacaa caccttctgc tttgataatc ccagaggact tgcccttcac    10200

cctcaatatg ggtacctcta ctgggcagac tggggtcacc gcgcatacat tgggagagta    10260

ggcatggatg gaaccaacaa gtctgtgata atctccacca agttagagtg gcctaatggc    10320

atcaccattg attacaccaa tgatctactc tactgggcag atgcccacct gggttacata    10380

gagtactctg atttggaggg ccaccatcga cacacggtgt atgatggggc actgcctcac    10440

cctttcgcta ttaccatttt tgaagacact atttattgga cagattggaa tacaaggaca    10500

gtggaaaagg gaaacaaata tgatggatca aatagacaga cactggtgaa cacaacacac    10560

agaccatttg acatccatgt gtaccatcca tataggcagc ccattgtgag caatccctgt    10620

ggtaccaaca atggtggctg ttctcatctc tgcctcatca agccaggagg aaaagggttc    10680

acttgcgagt gtccagatga cttccgcacc cttcagctga gtggcagcac ctactgcatg    10740

cccatgtgct ccagcaccca gttcctgtgc gctaacaatg aaaagtgcat tcctatctgg    10800

tggaaatgtg atggacagaa agactgctca gatggctctg atgaactggc cctttgcccg    10860

cagcgcttct gccgactggg acagttccag tgcagtgacg gcaactgcac cagcccgcag    10920

actttatgca atgctcacca aaattgccct gatgggtctg atgaagaccg tcttctttgt    10980

gagaatcacc actgtgactc caatgaatgg cagtgcgcca acaaacgttg catcccagaa    11040

tcctggcagt gtgacacatt taacgactgt gaggataact cagatgaaga cagttcccac    11100

tgtgccagca ggacctgccg gccgggccag tttcggtgtg ctaatggccg ctgcatcccg    11160

caggcctgga agtgtgatgt ggataatgat tgtggagacc actcggatga gcccattgaa    11220

gaatgcatga gctctgccca tctctgtgac aacttcacag aattcagctg caaaacaaat    11280

taccgctgca tcccaaagtg ggccgtgtgc aatggtgtag atgactgcag ggacaacagt    11340

gatgagcaag gctgtgagga gaggacatgc catcctgtgg gggatttccg ctgtaaaaat    11400

caccactgca tccctcttcg ttggcagtgt gatgggcaaa atgactgtgg agataactca    11460

gatgaggaaa actgtgctcc ccgggagtgc acagagagcg agtttcgatg tgtcaatcag    11520

cagtgcattc cctcgcgatg gatctgtgac cattacaacg actgtgggga caactcagat    11580

gaacgggact gtgagatgag gacctgccat cctgaatatt ttcagtgtac aagtggacat    11640

tgtgtacaca gtgaactgaa atgcgatgga tccgctgact gtttggatgc gtctgatgaa    11700

gctgattgtc ccacacgctt tcctgatggt gcatactgcc aggctactat gttcgaatgc    11760

aaaaaccatg tttgtatccc gccatattgg aaatgtgatg gcgatgatga ctgtggcgat    11820

ggttcagatg aagaacttca cctgtgcttg gatgttccct gtaattcacc aaaccgtttc    11880

cggtgtgaca acaatcgctg catttatagt catgaggtgt gcaatggtgt ggatgactgt    11940

ggagatggaa ctgatgagac agaggagcac tgtagaaaac cgacccctaa accttgtaca    12000

gaatatgaat ataagtgtgg caatgggcat tgcattccac atgacaatgt gtgtgatgat    12060

gccgatgact gtggtgactg gtccgatgaa ctgggttgca ataaaggaaa agaaagaaca    12120

tgtgctgaaa atatatgcga gcaaaattgt acccaattaa atgaaggagg atttatctgc    12180

tcctgtacag ctgggttcga aaccaatgtt tttgacagaa cctcctgtct agatatcaat    12240

gaatgtgaac aatttgggac ttgtccccag cactgcagaa ataccaaagg aagttatgag    12300

tgtgtctgtg ctgatggctt cacgtctatg agtgaccgcc ctggaaaacg atgtgcagct    12360

gagggtagct ctcctttgtt gctactgcct gacaatgtcc gaattcgaaa atataatctc    12420

tcatctgaga ggttctcaga gtatcttcaa gatgaggaat atatccaagc tgttgattat    12480

gattgggatc ccaaggacat aggcctcagt gttgtgtatt acactgtgcg aggggagggc    12540

tctaggtttg gtgctatcaa acgtgcctac atccccaact ttgaatccgg ccgcaataat    12600

cttgtgcagg aagttgacct gaaactgaaa tacgtaatgc agccagatgg aatagcagtg    12660

gactgggttg gaaggcatat ttactggtca gatgtcaaga ataaacgcat tgaggtggct    12720

aaacttgatg gaaggtacag aaagtggctg atttccactg acctggacca accagctgct    12780

attgctgtga atcccaaact agggcttatg ttctggactg actggggaaa ggaacctaaa    12840

atcgagtctg cctggatgaa tggagaggac cgcaacatcc tggttttcga ggaccttggt    12900

tggccaactg gcctttctat cgattatttg aacaatgacc gaatctactg gagtgacttc    12960

aaggaggacg ttattgaaac cataaaatat gatgggactg ataggagagt cattgcaaag    13020

gaagcaatga acccttacag cctggacatc tttgaagacc agttatactg gatatctaag    13080

gaaaagggag aagtatggaa acaaaataaa tttgggcaag gaaagaaaga gaaaacgctg    13140

gtagtgaacc cttggctcac tcaagttcga atctttcatc aactcagata caataagtca    13200

gtgcccaacc tttgcaaaca gatctgcagc cacctctgcc ttctgagacc tggaggatac    13260

agctgtgcct gtccccaagg ctccagcttt atagagggga gcaccactga gtgtgatgca    13320

gccatcgaac tgcctatcaa cctgcccccc ccatgcaggt gcatgcacgg aggaaattgc    13380

tattttgatg agactgacct ccccaaatgc aagtgtccta gcggctacac cggaaaatat    13440

tgtgaaatgg cgttttcaaa aggcatctct ccaggaacaa ccgcagtagc tgtgctgttg    13500

acaatcctct tgatcgtcgt aattggagct ctggcaattg caggattctt ccactataga    13560

aggaccggct cccttttgcc tgctctgccc aagctgccaa gcttaagcag tctcgtcaag    13620

ccctctgaaa atgggaatgg ggtgaccttc agatcagggg cagatcttaa catggatatt    13680

ggagtgtctg gttttggacc tgagactgct attgacaggt caatggcaat gagtgaagac    13740

tttgtcatgg aaatggggaa gcagcccata atatttgaaa acccaatgta ctcagccaga    13800

gacagtgctg tcaaagtggt tcagccaatc caggtgactg tatctgaaaa tgtggataat    13860

aagaattatg gaagtcccat aaacccttct gagatagttc cagagacaaa cccaacttca    13920

ccagctgctg atggaactca ggtgacaaaa tggaatctct tcaaacgaaa atctaaacaa    13980

actaccaact ttgaaaatcc aatctatgca cagatggaga acgagcaaaa ggaaagtgtt    14040

gctgcgacac cacctccatc accttcgctc cctgctaagc ctaagcctcc ttcgagaaga    14100

gacccaactc caacctattc tgcaacagaa gacactttta aagacaccgc aaatcttgtt    14160

aaagaagact ctgaagtata gctataccag ctatttaggg aataattaga aacacacttt    14220

tgcacatata ttttttacaa acagatgaaa aaagttaaca ttcagtactt tatgaaaaaa    14280

atatattttt ccctgtttgc ctatagttgg aggtatcctg tgtgtctttt tttacttatg    14340

ccgtctcata tttttacaaa taattatcac aatgtactat atgtatatct ttgcactgaa    14400

gttgtctgaa ggtaatacta taaatatatt gtatatttgt aaattttgga aagattatcc    14460

tgttactgaa tttgctaata aagatgtctg ctgatttggt tggtgatcat tatagtaaat    14520

gatccaacaa gaaaaggaat tgactgggga cctttagccg tgtctaaaga agaggcacca    14580

ctcatatttc ctataaaatt atctaggaaa ggaatccagg ccccgctctt gggtccattt    14640

ttacacatta gcacttaatt aatgttcaat attacatgtc aatttgatta atggctatgt    14700

tgataggggc cactatgtgt tgtatagaca tctggacttg actgtagact cctcagataa    14760

tacagaaggt aggaaaagca attcagtttg gcccttctgt gtgttggcat tgtctaacca    14820

gaactctctg tttcatgtgt gttctctcac tagctgccaa gacaacattt ttatttgtga    14880

tgtctatgag gaaatcccat atcattaagt gccagtgtcc tgcattgagt ttgtggttaa    14940

ttaaatgagc tcttctgctg atggaccctg gagcaatttc tcccctcacc tgacattcaa    15000

ggtggtcacc tgccctagta gttggagctc agtagctgaa tttctgaaac caaatctgtg    15060

tcttcataaa ataaggtgca aaaaaaaaaa ataccagtta agtaaagcct caactgggtt    15120

tttgtttcta tgaaaatatc attataatca ctatttattt cctaagttga acctgaatag    15180

aaagggaaac cattcttatt aagcttttta ttaggccctg tggctaaatg tgtacattta    15240

tattagaatg tactgtacag tccagatctt ttctttaatt cttattggtt tttttttttt    15300

tttttttttt agagatggag tcttgctata ttgccaaggc tgatcttgaa gtcctgggct    15360

caagtgatcc tcccacctca gcctcctgag tggttggggt tacgggcgtg agccactgtg    15420

cctggcttcc agctctcctc ttaaatagtg ggtatagtct gcacaacagg aaccatggca    15480

ggaatataca ctttcccata gcaaatagca tacctgactc tctgtgctaa tattgcacat    15540

ttgttaaaca atgaatgaat ggatggatgg atggatggat gaatgaatga aacatatact    15600

actgattatt ttattccaga gttctcaaaa tatttgttgc tgatattttg agtgctgact    15660

gtaattactt tgattagata aacaactgga aataatgctg ctgaaaaagt tctaataaat    15720

gtgtatttta tcaga                                                     15735


<210>  1296
<211>  1890
<212>  DNA
<213>  homo sapiens

<400>  1296
gaagaagttg gttcttgtct cgaatacttt tcctcccgtg ccccgcccct tgaatcagag       60

gcggctgtct cgtgcggcta gagcagggcc agtagagttc ggggcagctg tcaaaaacga      120

gacggggagg cttttcttcc cgggggtgga ggagggaagg agggaggtgt ccttttttcc      180

atctgttgca gtttccgaac caaacgcacc ctcgccagcc ccgggaagaa aggcccaagg      240

gagaaacctg gggcgctcgg ctggtgcccc caccgccggg cgagggatgc gggcggtccg      300

tgcgcggcag gcggaaagga tcgtgtttct ggacccggcc accccccgcg tccgcaccgc      360

cgcccccgag ggacgagtga cagcggccgc cgcgctcggt ccagtcttcc cggctggaag      420

gagcgggcgc ctgggatcag agcgtcctgt ttagcaataa cggctggagc acgtcctaca      480

agttacggga gagtcggctg tgaaggagac gttcgcttat cccctgtgtc cccgctcctg      540

gcccctccag acccccgcct tgcctcgcgc tgggagggga gatccagaat gaaaggcaag      600

aaaggtattg ttgcagcatc tggcagtgag actgaggatg aggacagcat ggacattccc      660

ttggaccttt cttcatccgc tggctcaggc aagagaagga gaaggggcaa cctacccaag      720

gagtctgtgc agattcttcg ggattggctg tatgagcacc gttacaatgc ctatccttca      780

gagcaagaaa aagcgttgct gtcccagcaa acacacctgt ctacgctaca ggtctgtaac      840

tggttcatca acgcccgccg caggctcctc cctgacatgc tgagaaagga tggcaaagat      900

ccaaatcagt tcacaatttc ccgccgtggg gccaagattt ctgaaacgag ctctgtggag      960

tccgtgatgg gcatcaaaaa cttcatgcca gctctagagg agaccccatt tcattcctgt     1020

acagctgggc caaacccaac cctagggagg ccactgtctc ctaagccgtc atccccggga     1080

tcagttttgg ctcgtccatc agtgatctgc cataccactg tgactgcatt gaaagatgtc     1140

cctttctctc tctgccagtc ggtcggtgtg ggacaaaaca cagatataca gcagatagcg     1200

gccaaaaact tcacagacac ctctctcatg tacccagagg acacttgtaa atctggacca     1260

agtacgaata cacagagtgg tcttttcaac actcctcccc ctactccacc ggacctcaac     1320

caggacttca gtggatttca gcttctagtg gatgttgcac tcaaacgggc tgcagagatg     1380

gagcttcagg caaaacttac agcttaaccc attttcaagc aaaacagttc tcagaaatgt     1440

catgattgcc ggggtgaagg caagagatga attgcattat tttatatatt ttttattaat     1500

atttgcacat gggattgcta aaacagcttc ctgttactga gatgtcttca atggaataca     1560

gtcattccaa gaactataaa cttaaagcta ctgtagaaac aaagggtttt cttttttaaa     1620

tgtttcttgg tagattattc ataatgtgag atggttccca atatcatgtg attttttttt     1680

tcctcccctt cccttttttt gttatttttt cagactgtgc aatacttaga gaacctatag     1740

catcttctca ttcccatgtg gaacaggatg cccacatact gtctaattaa taaattttcc     1800

attttttttc aaacaagtat gaatctagtt ggttgatgcc ttttttttca tgacataata     1860

aagtattttc tttaaaaaaa aaaaaaaaaa                                      1890


<210>  1297
<211>  1706
<212>  DNA
<213>  homo sapiens

<400>  1297
gaagaagttg gttcttgtct cgaatacttt tcctcccgtg ccccgcccct tgaatcagag       60

gcggctgtct cgtgcggcta gagcagggcc agtagagttc ggggcagctg tcaaaaacga      120

gacggggagg cttttcttcc cgggggtgga ggagggaagg agggaggtgt ccttttttcc      180

atctgttgca gtttccgaac caaacgcacc ctcgccagcc ccgggaagaa aggcccaagg      240

gagaaacctg gggcgctcgg ctggtgcccc caccgccggg cgagggatgc gggcggtccg      300

tgcgcggcag gcggaaagga tcgtgtttct ggacccggcc accccccgcg tccgcaccgc      360

cgcccccgag ggacgagtga cagcggccgc cgcgctcggt ccagtcttcc cggctggaag      420

gtattgttgc agcatctggc agtgagactg aggatgagga cagcatggac attcccttgg      480

acctttcttc atccgctggc tcaggcaaga gaaggagaag gggcaaccta cccaaggagt      540

ctgtgcagat tcttcgggat tggctgtatg agcaccgtta caatgcctat ccttcagagc      600

aagaaaaagc gttgctgtcc cagcaaacac acctgtctac gctacaggtc tgtaactggt      660

tcatcaacgc ccgccgcagg ctcctccctg acatgctgag aaaggatggc aaagatccaa      720

atcagttcac aatttcccgc cgtggggcca agatttctga aacgagctct gtggagtccg      780

tgatgggcat caaaaacttc atgccagctc tagaggagac cccatttcat tcctgtacag      840

ctgggccaaa cccaacccta gggaggccac tgtctcctaa gccgtcatcc ccgggatcag      900

ttttggctcg tccatcagtg atctgccata ccactgtgac tgcattgaaa gatgtccctt      960

tctctctctg ccagtcggtc ggtgtgggac aaaacacaga tatacagcag atagcggcca     1020

aaaacttcac agacacctct ctcatgtacc cagaggacac ttgtaaatct ggaccaagta     1080

cgaatacaca gagtggtctt ttcaacactc ctccccctac tccaccggac ctcaaccagg     1140

acttcagtgg atttcagctt ctagtggatg ttgcactcaa acgggctgca gagatggagc     1200

ttcaggcaaa acttacagct taacccattt tcaagcaaaa cagttctcag aaatgtcatg     1260

attgccgggg tgaaggcaag agatgaattg cattatttta tatatttttt attaatattt     1320

gcacatggga ttgctaaaac agcttcctgt tactgagatg tcttcaatgg aatacagtca     1380

ttccaagaac tataaactta aagctactgt agaaacaaag ggttttcttt tttaaatgtt     1440

tcttggtaga ttattcataa tgtgagatgg ttcccaatat catgtgattt tttttttcct     1500

ccccttccct ttttttgtta ttttttcaga ctgtgcaata cttagagaac ctatagcatc     1560

ttctcattcc catgtggaac aggatgccca catactgtct aattaataaa ttttccattt     1620

tttttcaaac aagtatgaat ctagttggtt gatgcctttt ttttcatgac ataataaagt     1680

attttcttta aaaaaaaaaa aaaaaa                                          1706


<210>  1298
<211>  2088
<212>  DNA
<213>  homo sapiens

<400>  1298
tccgctccgt tcggccggtt ctcccgggaa gctattaata gcattacgtc agcctgggac       60

tggcaacacg gagtaaacga ccgcgccgcc agcctgaggg ctataaaagg ggtgatgcaa      120

cgctctccaa gccacagtcg cacgcagcca ggcgcgcact gcacagctct cttctctcgc      180

cgccgcccga gcgcaccctt cagcccgcgc gccggccgtg agtcctcggt gctcgcccgc      240

cggccagaca aacagcccgc ccgaccccgt cccgaccctg gccgccccga gcggagcctg      300

gagcaaaatg atgcttcaac acccaggcca ggtctctgcc tcggaagtga gtgcttctgc      360

catcgtcccc tgcctgtccc ctcctgggtc actggtgttt gaggattttg ctaacctgac      420

gccctttgtc aaggaagagc tgaggtttgc catccagaac aagcacctct gccaccggat      480

gtcctctgcg ctggaatcag tcactgtcag cgacagaccc ctcggggtgt ccatcacaaa      540

agccgaggta gcccctgaag aagatgaaag gaaaaagagg cgacgagaaa gaaataagat      600

tgcagctgca aagtgccgaa acaagaagaa ggagaagacg gagtgcctgc agaaagagtc      660

ggagaagctg gaaagtgtga atgctgaact gaaggctcag attgaggagc tcaagaacga      720

gaagcagcat ttgatataca tgctcaacct tcatcggccc acgtgtattg tccgggctca      780

gaatgggagg actccagaag atgagagaaa cctctttatc caacagataa aagaaggaac      840

attgcagagc taagcagtcg tggtatgggg gcgactgggg agtcctcatt gaatcctcat      900

tttataccca aaaccctgaa gccattggag agctgtcttc ctgtgtacct ctagaatccc      960

agcagcagag aaccatcaag gcgggagggc ctgcagtgat tcagcaggcc cttcccattc     1020

tgccccagag tgggtcttgg accagggcaa gtgcatcttt gcctcaactc caggatttag     1080

gccttaacac actggccatt cttatgttcc agatggcccc cagctggtgt cctgcccgcc     1140

tttcatctgg attctacaaa aaaccaggat gcccaccgtt aggattcagg cagcagtgtc     1200

tgtacctcgg gtgggaggga tggggccatc tccttcaccg tggctaccat tgtcactcgt     1260

aggggatgtg gagtgagaac agcatttagt gaagttgtgc aacggccagg gttgtgcttt     1320

ctagcaaata tgctgttatg tccagaaatt gtgtgtgcaa gaaaactagg caatgtactc     1380

ttccgatgtt tgtgtcacac aacactgatg tgacttttat atgctttttc tcagatctgg     1440

tttctaagag ttttgggggg cggggctgtc accacgtgca gtatctcaag atattcaggt     1500

ggccagaaga gcttgtcagc aagaggagga cagaattctc ccagcgttaa cacaaaatcc     1560

atgggcagta tgatggcagg tcctctgttg caaactcagt tccaaagtca caggaagaaa     1620

gcagaaagtt caacttccaa agggttagga ctctccactc aatgtcttag gtcaggagtt     1680

gtgtctaggc tggaagagcc aaagaatatt ccattttcct ttccttgtgg ttgaaaacca     1740

cagtcagtgg agagatgttt ggaaaccaca gtcagtggag cctgggtggt acccaggctt     1800

tagcattatt ggatgtcaat agcattgttt ttgtcatgta gctgttttaa gaaatctggc     1860

ccagggtgtt tgcagctgtg agaagtcact cacactggcc acaaggacgc tggctactgt     1920

ctattaaaat tctgatgttt ctgtgaaatt ctcagagtgt ttaattgtac tcaatggtat     1980

cattacaatt ttctgtaaga gaaaatatta cttatttatc ctagtattcc taacctgtca     2040

gaataataaa tattggaacc aagacatggt aaacaaaaaa aaaaaaaa                  2088


<210>  1299
<211>  1935
<212>  DNA
<213>  homo sapiens

<400>  1299
ggcggaggtg gggttagctt cagttgacca accatgcctt gaggataaat tggatgggat       60

cagatgggaa gatgtgacaa gaagagaaat cctcctctat ataggatgct ctgctgtttc      120

ctaaggattt tcagcacctt gccccaaaat caaaatgatg cttcaacacc caggccaggt      180

ctctgcctcg gaagtgagtg cttctgccat cgtcccctgc ctgtcccctc ctgggtcact      240

ggtgtttgag gattttgcta acctgacgcc ctttgtcaag gaagagctga ggtttgccat      300

ccagaacaag cacctctgcc accggatgtc ctctgcgctg gaatcagtca ctgtcagcga      360

cagacccctc ggggtgtcca tcacaaaagc cgaggtagcc cctgaagaag atgaaaggaa      420

aaagaggcga cgagaaagaa ataagattgc agctgcaaag tgccgaaaca agaagaagga      480

gaagacggag tgcctgcaga aagagtcgga gaagctggaa agtgtgaatg ctgaactgaa      540

ggctcagatt gaggagctca agaacgagaa gcagcatttg atatacatgc tcaaccttca      600

tcggcccacg tgtattgtcc gggctcagaa tgggaggact ccagaagatg agagaaacct      660

ctttatccaa cagataaaag aaggaacatt gcagagctaa gcagtcgtgg tatgggggcg      720

actggggagt cctcattgaa tcctcatttt atacccaaaa ccctgaagcc attggagagc      780

tgtcttcctg tgtacctcta gaatcccagc agcagagaac catcaaggcg ggagggcctg      840

cagtgattca gcaggccctt cccattctgc cccagagtgg gtcttggacc agggcaagtg      900

catctttgcc tcaactccag gatttaggcc ttaacacact ggccattctt atgttccaga      960

tggcccccag ctggtgtcct gcccgccttt catctggatt ctacaaaaaa ccaggatgcc     1020

caccgttagg attcaggcag cagtgtctgt acctcgggtg ggagggatgg ggccatctcc     1080

ttcaccgtgg ctaccattgt cactcgtagg ggatgtggag tgagaacagc atttagtgaa     1140

gttgtgcaac ggccagggtt gtgctttcta gcaaatatgc tgttatgtcc agaaattgtg     1200

tgtgcaagaa aactaggcaa tgtactcttc cgatgtttgt gtcacacaac actgatgtga     1260

cttttatatg ctttttctca gatctggttt ctaagagttt tggggggcgg ggctgtcacc     1320

acgtgcagta tctcaagata ttcaggtggc cagaagagct tgtcagcaag aggaggacag     1380

aattctccca gcgttaacac aaaatccatg ggcagtatga tggcaggtcc tctgttgcaa     1440

actcagttcc aaagtcacag gaagaaagca gaaagttcaa cttccaaagg gttaggactc     1500

tccactcaat gtcttaggtc aggagttgtg tctaggctgg aagagccaaa gaatattcca     1560

ttttcctttc cttgtggttg aaaaccacag tcagtggaga gatgtttgga aaccacagtc     1620

agtggagcct gggtggtacc caggctttag cattattgga tgtcaatagc attgtttttg     1680

tcatgtagct gttttaagaa atctggccca gggtgtttgc agctgtgaga agtcactcac     1740

actggccaca aggacgctgg ctactgtcta ttaaaattct gatgtttctg tgaaattctc     1800

agagtgttta attgtactca atggtatcat tacaattttc tgtaagagaa aatattactt     1860

atttatccta gtattcctaa cctgtcagaa taataaatat tggaaccaag acatggtaaa     1920

caaaaaaaaa aaaaa                                                      1935


<210>  1300
<211>  3512
<212>  DNA
<213>  homo sapiens

<400>  1300
agaaaggcgc gcgaaggcgc ggaggaggcg tcggctgcgg cgcccactcc ccctagtccc       60

agcgccctgc cgctcgcctc ccgctgccgg gcgccggcgc gctcggctct ttccgccgcc      120

gccgctgccg cgcggtggcc cgtgcgcctc ggcaccttcg gcaatttccg tcgggcccca      180

gccgccattt tctcgccgct tgtgtggctc gctggctgcg tggctcggtt cttgtgagcg      240

aagctttgtc cggttcggca atggacggaa tcgtcactga ggttgcagtt ggcgtgaaga      300

gaggatctga cgaactactc tcaggcagtg ttctcagtag tccgaactct aatatgagca      360

gcatggtagt tacagccaat ggtaatgata gtaaaaaatt taaaggagaa gataaaatgg      420

atggtgctcc ttctcgtgta cttcatattc gaaaattacc tggggaagta acagaaactg      480

aagttattgc tttaggctta ccttttggta aggtgaccaa catccttatg ctgaaaggaa      540

aaaatcaggc atttttggaa ctagcaaccg aggaagcagc tattactatg gttaattact      600

attctgctgt gacacctcat cttcgtaacc aaccaatata tatccagtac tcgaatcaca      660

aagaactaaa gacagataat acattaaacc aacgtgctca ggcagttctt caagctgtga      720

cagctgtcca gacagcaaat actcctctta gtggcaccac agttagcgag agtgcagtga      780

ctccagccca gagtccagta cttagaataa ttattgacaa catgtactac cctgtaacac      840

ttgatgttct tcaccaaata ttttctaagt ttggtgctgt attgaagata atcacattta      900

caaaaaataa ccagtttcaa gctttgctcc agtatggtga tccagtaaat gctcaacaag      960

caaaactagc cctagatggt cagaatattt ataatgcctg ctgtacccta aggattgatt     1020

tttccaaact tgtgaatttg aatgtaaaat acaacaatga taaaagtagg gattatactc     1080

gacctgatct tccatctggg gatggacaac ctgcattgga cccagctatt gctgcagcat     1140

ttgccaagga gacatccctc ttagctgttc caggagctct gagtcctttg gccattccaa     1200

atgctgctgc agcagctgct gcagctgctg ctggccgagt gggtatgcct ggagtctcag     1260

ctggtggcaa tacagtcctg ttggttagca atttaaatga agagatggtt acgccccaaa     1320

gtctgtttac cctcttcggt gtttatggag atgtgcagcg tgtgaagatt ttatacaata     1380

agaaagacag cgctctaata cagatggctg atggaaacca atcacaactt gccatgaatc     1440

atcttaatgg acagaaaatg tatggaaaaa ttattcgtgt tactctgtct aaacatcaga     1500

ctgtacagct acctcgagag ggacttgatg atcaagggct aacaaaagat tttggtaatt     1560

ccccattgca tcgttttaag aaacctggat ccaaaaattt tcaaaacatt tttcctcctt     1620

ctgccaccct tcacctatct aatatccctc catcagtagc agaagaggat ctacgaacac     1680

tgttcgctaa cactgggggc actgtgaaag catttaagtt ttttcaagat cacaaaatgg     1740

ctcttcttca gatggcaaca gtggaagaag ctattcaggc cttgattgat cttcataatt     1800

ataaccttgg agaaaaccat catctgagag tgtctttctc caagtcaaca atttaaaaat     1860

gggaagatga agattggggg tgaatcacat tgttcaatgt catcacctat ttgactgttc     1920

agaaaagtgg ggaccagagt ttgatttttt ttgtttttgt ttttttgggg tttctttttt     1980

ttttccatgc tgttatcatt ccttggttat aaaatgaaat ggcatatgta aaggcagagt     2040

tgttaactgc tatatttcat ctgttctata gggaagccat tttgtctgtt taaaatttca     2100

gtttaatttt gctttttttt tttttttttt tttcctttca acttagttga catacgtgcc     2160

ttaaaaagga aaactagtgt tgctattgtg catttactag aaaaaaggaa ttggttgttt     2220

agggcacact gttatatggg aattaaaata tgtttaggca ggggtgtgta aaaaggttaa     2280

gtttttgttt ctcctgcttg gaacttattt tgaattactg gcttgtcacc tttttttcta     2340

tttaatcaaa taagatacat gatattgaaa gaataaagca gcatttttag tttttactac     2400

cttaggcttt attgctttga aaacaacatt ggccttttgt atctcacaat tctggtctag     2460

attcagttat gaatgtaggc attagttaaa attaacaaga tgcagagtat taatttctta     2520

agacaacaaa gtgatttctg taagtttgag ccctatgtgg aaagcattgt ggaatcttaa     2580

ccttttcgta cacactcttg tgggacgtat catataaatg tcagcactaa gtaatgtctt     2640

gtttgtggct gaatattttt cgtagatgtt tttgaagttg acatgactta cgtgcattta     2700

aatatatatt gccatcctta gtttgtaatt aagatttgga atatggttgt ggatttctga     2760

gcatgtgcag actggtctag ctagttcagg aactggtgca tgtatttttc aaagataaag     2820

aaagtgtact gcgaaaatat gcaggaagat taattttgtg gcagttttct aaaactgaca     2880

accaggtggg accaaagttt atgtgccttt agtcttaatt taccttgcat tgtaatattc     2940

agttttaata aatcttcaaa atattttgta tttaggaata gatctgactt taataaaaac     3000

atggctcaga atctacaggt caaattaatt tgaacagttc ttgtcaatcc gaattgttga     3060

ttctgtttaa atgaccaata ctttttgaaa ttgatgtact tagtttcaag attcatagat     3120

tctgttatct atgtagacag aatggtcatg tatattttct attagttgag tttttacatc     3180

tttagaaatg taaaattcag tatagtttga aagcggcaca attaaaaatt aattttctaa     3240

caaagttggg aggtttgatg gttgtttaat ttcattttgt gtgtactctg cttacccctg     3300

tagcatgctc aataaacact tctgtagctc tatattcacc ttttctgtct ttctctgctg     3360

ccttttctct ctcctcttct ttgttttcac tccactgtgc ttctgaattc atgtttattc     3420

tctgccaggg tgggaaagga gtaataatat tacaattcta tggctttata ccataaataa     3480

atctagatgc tgtgaaaata aaaaaaaaaa aa                                   3512


<210>  1301
<211>  1220
<212>  DNA
<213>  homo sapiens

<400>  1301
atgcacacat acgcgcgcgc acatgcacat aggcacacag agatacgcgc acacacacac       60

acaaacgcac tcagatttcc cggaccctgg ttttcctcct gtgacccttt cggggccggg      120

ctctcaccct aaagaagcag ccccgccctg gggtggcccc accctctctt gggacctgtc      180

ataagtcgga ccccgggcgc ccggctgcgc agtcccagcc gccttcccca ggcagtggaa      240

ccttcgggct cctgagcttc aggatggttc gtactaagac atggaccctg aagaagcact      300

ttgttggcta tcctactaat agtgactttg agttgaagac agctgagctc ccacccttaa      360

aaaatggaga ggtcctgctt gaagctttgt tcctcaccgt ggatccctac atgagagtgg      420

cagccaaaag attgaaggaa ggtgatacaa tgatggggca gcaagtggcc aaagttgtgg      480

aaagtaaaaa tgtagcccta ccaaaaggaa ctattgtact ggcttctcca ggctggacaa      540

cgcactccat ttctgatggg aaagatctgg aaaagctgct gacagagtgg ccagacacaa      600

taccactgtc tttggctctg gggacagttg gcatgccagg cctgactgcc tactttggcc      660

tacttgaaat ctgtggtgtg aagggtggag aaacagtgat ggttaatgca gcagctggag      720

ctgtgggctc agtcgtgggg cagattgcaa agctcaaggg ctgcaaagtt gttggagcag      780

tagggtctga tgaaaaggtt gcctaccttc aaaagcttgg atttgatgtc gtctttaact      840

acaagacggt agagtctttg gaagaaacct tgaagaaagc gtctcctgat ggttatgatt      900

gttattttga taatgtaggt ggagagtttt caaacactgt tatcggccag atgaagaaat      960

ttggaaggat tgccatatgt ggagccatct ctacatataa cagaaccggc ccacttcccc     1020

caggcccacc cccagagatt gttatctatc aggagcttcg catggaagct tttgtcgtct     1080

accgctggca aggagatgcc cgccaaaaag ctctgaagga cttgctgaaa tgggtcttag     1140

agatcaaaag agaaaatgaa gaagattgaa gcttcaaagc agaaaaatga agggaatatg     1200

tatcattcac cattacctta                                                 1220


<210>  1302
<211>  2926
<212>  DNA
<213>  homo sapiens

<400>  1302
aagagtgtgg atagtgggct ctgcggataa ctcagacgcc attaagctgg ggaatccaaa       60

ctctaaaaga aggacgcatt ttaggtaaga tctagtggct agatcttcag ggtgggcttc      120

gttcttgtgg aaatcagtca agaaagatcg gattcgcggt tatttatgca aatcatctgg      180

gtggattgtg tacggagtta aactgcgcct tctggaccgg gtctgaacaa tggagactgc      240

gctagcaaaa acgccacaga aaaggcaagt tatgtttctt gctatattgt tgcttttgtg      300

ggaggctggc tctgaggcag ttaggtattc cataccagaa gaaacagaaa gtggctattc      360

tgtggccaac ctggcaaaag acctgggtct tggggtgggg gaactggcca ctcggggcgc      420

gcgaatgcat tacaaaggaa acaaagagct cttgcagctt gatataaaga ccggcaattt      480

gcttctatat gaaaaactag accgggaggt gatgtgcggg gcgacagaac cctgtatatt      540

gcatttccag ctcttactag aaaatccagt gcagtttttt caaactgatc tgcagctcac      600

agatataaat gaccatgccc cagagttccc agagaaggaa atgctcctaa aaatcccaga      660

gagcacccag ccagggactg tgtttccctt aaaaatagcc caggactttg acataggtag      720

caacactgtt cagaactaca caatcagccc aaattcacac tttcatgttg ctacgcataa      780

tcgcggagat ggcagaaaat acccagagct ggtgctggac aaagcgctgg accgggagga      840

gcggcctgag ctcagcttaa cactcactgc actggacggt ggggctccgc ccaggtccgg      900

gaccaccaca attcgcattg tcgtcttgga taataatgac aacgcccccg aatttttaca      960

atcattctat gaggtacagg tgcccgagaa cagccccctt aactccttag ttgtcgttgt     1020

ctccgctcga gatttagatg caggagcata tgggagtgta gcctatgctc tattccaagg     1080

cgatgaagtt actcaaccat ttgtaataga cgagaaaaca gcagaaattc gcctgaaaag     1140

ggcattggat ttcgaggcaa ctccatatta taacgtggaa attgtagcca cagatggtgg     1200

gggcctttca ggaaaatgca ctgtggctat agaagtggtg gatgtgaatg acaacgcccc     1260

tgaactcacc atgtctacgc tctccagccc taccccagaa aatgccccgg aaactgtagt     1320

tgccgttttc agtgtttctg atccagactc cggggacaac ggtaggatga tttgctccat     1380

ccagaatgat ctcccctttc ttttgaagcc cacattaaaa aacttttaca ccctagtgac     1440

acagagaaca ctggacagag agagccaagc cgagtacaac atcaccatca ctgtcaccga     1500

catggggaca cccaggctga aaaccgagca caacataacg gtcctggtct ccgacgtcaa     1560

tgacaacgcc cccgccttca cccaaacctc ctacaccctg ttcgtccgag agaacaacag     1620

ccccgccctg cacatcggca gtgtcagcgc cacagacaga gactcaggca ccaacgccca     1680

ggtcacctac tcgctgctgc cgccccagaa cccacacctg cgcctcgcct ccctggtctc     1740

catcaacgcg gacaacggcc acctgtttgc cctcaggtcg ctggactacg aggccctgca     1800

ggcgttcgag ttccgcgtgg gagccacaga ccgcggctcc ccggcgctga gcagcgaggc     1860

gctggtgcgc gtgctggtgc tggacgccaa cgacaactcg cccttcgtgc tgtatccgct     1920

gcagaacggc tcggcgcctt gcaccgagct ggtgccccgg gcggccgagc cgggctacct     1980

ggtgaccaag gtggtggcgg tggacggtga ctcgggccag aacgcctggc tgtcgtacca     2040

gctgctcaag gccacggagc ccgggctgtt cagcatgtgg gcgcacaatg gcgaggtgcg     2100

caccgccagg ctgctgagcg agcgcgacgc ggccaagcac aggctggtgg tgctggtcaa     2160

ggacaatggc gagcctccgc gctcggccac cgccacgctg cacgtgctcc tggtggacgg     2220

cttctcccag ccctacctgc cgctgccgga ggcggccccg gcccaggccc aggccgactc     2280

gctcactgtc tacctggtgg tggcattggc ctcggtgtcg tcgctcttcc tcttttcggt     2340

gctcctgttc gtggcagtgc ggctgtgcag gaggagcagg gcggccccgg tcggtcgctg     2400

ctcggtgccc gagggcccct ttccagggca tctggtggac gtgagcggca ccgggaccct     2460

atcccagagc taccactacg aggtgtgttt gaccggagac tcaggggccg gcgagttcaa     2520

gttcctgaag ccgattattc ctaacctttt gccccagggc gctggtgaag aaatagggaa     2580

aactgctgcc ttccggaata gctttggatt aaattagaga tctcgtgatg acgcgttgtt     2640

ttctgccatt tatcccaaac tttttcagat ctagaattcg agagtgtcat ggacaaaaat     2700

ttcaccttga gattgagctt ttatttccct ttttaatgga tttgtctgtt gaacttcatg     2760

ctgtccaagt gttgaaaagt caattttatt tcattgcatt tatttacata gtgtcattcc     2820

aaatccatgc atgctgttga ttttcctgag atttttttct cttcttgttg gtatttgttg     2880

tgataaacca ccttaataaa atcaagtatt aattttattt tcaaaa                    2926


<210>  1303
<211>  3224
<212>  DNA
<213>  homo sapiens

<400>  1303
ggagatatta caggggaccc agcccgcagc gacaggcaca aagtcacggg gtaatgaact       60

tcggggaccc ttcgccgctg cgtgcgcggc tctccccgga aacccggacc tggccgcctc      120

ttccctcgga agatttccca gcaatctagt tttcccactc tgcgcttggg ttccggcagc      180

gcggagcccg tctgcctctg agactgcggt agtgttttcc ttctttcctt gggagaccag      240

cggtcggcag agattgccca cactctgcat gcctatgtag agggagagat cgaagactga      300

gtgacaggaa tggggaaaaa gagggatttc gctccgtagg aaggccattt tcgtgtctcc      360

atctctgtct ttcaacatcc ctctcttgct gttcttcctt cttcctcagt cttcctgtcc      420

atctctccat ctgtctgtcc atgtgtgtgt ccatatcaag cagcattccc agcagctgcg      480

gttttgcaag agccgggaag aaacttaagg atgcttaaat ttccactgtt ggacgaattc      540

tgagcgccca gggagcagcg cagcgcgcga ctgacaccca cctgtcccgc ccaggagcct      600

tgcaggctgg agggcagctg gagagcggcg gcgcccggcg gcgaggcggg cgctgccggc      660

cgggactcgg gcagcgccca ccaaccgctc cgccccggga cagccagcat gagcaagcca      720

gccggatcaa caagccgcat tttagatatc ccctgcaaag tgtgtggcga ccgcagctcg      780

gggaagcact acggggtcta cgcctgcgac ggctgctcag gttttttcaa acggagcatc      840

cgaaggaata ggacctatgt ctgcaaatct ggaaaccagg gaggctgtcc ggtggacaag      900

acgcacagaa accagtgcag ggcgtgtcgg ctgaagaagt gtttggaagt caacatgaac      960

aaagacgccg tgcagcacga gcgggggcct cggacgtcca ccatccgcaa gcaagtggcc     1020

ctctacttcc gtggacacaa ggaggagaac ggggccgccg cgcactttcc ctcggcggcg     1080

ctccctgcgc cggccttctt caccgcggtc acgcagctgg agccgcacgg cctggagctg     1140

gccgcggtgt ccaccactcc agagcggcag accctcgtga gcctggctca gcccacgccc     1200

aagtaccccc atgaagtgaa tgggacccca atgtatctct atgaagtggc cacggagtcg     1260

gtgtgtgaat cagctgccag acttctcttc atgagcatca agtgggctaa gagtgtgcca     1320

gccttctcca cgctgtcttt gcaagaccag ctgatgcttt tggaagatgc ttggagagaa     1380

ctgtttgttc taggaatagc acaatgggcc attccggttg atgctaacac tctactggct     1440

gtatctggca tgaacggtga caacacagat tcccagaagc tgaacaagat catatctgaa     1500

atacaggctt tacaagaggt ggtggctcga tttagacaac tccggttaga tgctactgaa     1560

tttgcctgtc taaaatgcat cgtcactttc aaagccgttc ctacacatag tggttctgaa     1620

ctgagaagtt tccggaatgc tgccgccatt gcagcccttc aagatgaggc tcagctaacg     1680

ctcaacagct acatccatac cagatatccc actcaaccct gtcgctttgg aaaactcctg     1740

ttgcttttgc cagctttacg ttctattagc ccatcaacta tagaagaagt gtttttcaaa     1800

aaaaccatcg gcaatgtgcc aattacaaga ctgctttcag atatgtacaa atccagtgat     1860

atctaagctc acaagatacc cacttttcag gatgggacag tatcagatga acttcaaccc     1920

atggagaaca agcctcaact aacaaaccct tcaggaagca tataccgggg aatgtgtagc     1980

cttcaggaaa aaaatgccaa ttgacacaaa gcattccagt agctatgacc tgccgccctg     2040

accaggatag ggcgggtggg aaggagaggg gtgcaacagg accgcctgca ctgaaaactc     2100

actgctgcca tgccctggga gggggcaaac tgggggttgc cacaggccgt gccattctgc     2160

ctcttacctg gaagatcagg ctgaacgatc aaaagctgaa acataagtag tgctttctct     2220

tcctttttag catacaaagt ttggtaacca aatatagctc tgtgtataac atcgtactgc     2280

ggccttcaaa actacgttat gttggagcat ttattttaaa aataatggta ggttttaaat     2340

taaaagtgtt atcaaaagtt tcccctctat tgtaatacat tattaagtgg ccttcagaac     2400

tgagttaata agtgaaaagt agcttatgcc atgtgatttg ctttttctct atcttctttt     2460

ttcttttctt tctctttctt ttgttctttc ttcttctttt ttaataccat aggccaggca     2520

accttgtcaa aggaattgat ggacaaaatg agattctcac caggacttca ggttggataa     2580

catgtcaaaa agagaagagc tttactaaaa gaacataagt caagggagga tgaataaaaa     2640

cagcaaaacc aaataaagtg gagatgagtg attgagtgag gtagattgct gtcccgttaa     2700

catagtgctg aaaccaaagg cagtgggggt ccaaactcgt ggtgcagcaa gtcacaccag     2760

acaggaaacg aatatggacg taattgcaga aggaacttca aggagatgaa tgaatgctaa     2820

aagggttctt gactgatcca ttgctaacag cctgagactc ttcaatgcct ttccgaaaac     2880

tggtttctag taaagccttg aatgaacaca cacacacaca cacacacaca cacacacaca     2940

cacacacaca cacaccgtcc tacactttaa gctgctcctt tggtatgact ctatacttat     3000

ggaaatgtag aaacaaacat ttttaaatag ctgctgtact tttcacattt tgatttatta     3060

ggtactagca ctgaggaaaa aaaattcagc acttggacta tcataggatg agtaaaactt     3120

ttcttgtaca aagtgaatta actgatttgt gaagttaaaa ggttgtactc attgtattta     3180

caaagaataa aaatatattg aatttaaatg aaaaaaaaaa aaaa                      3224


<210>  1304
<211>  2987
<212>  DNA
<213>  homo sapiens

<400>  1304
agcagtgttc tcttcgtccc cctcccccaa actgaggatt gggcaatacc acagaacctc       60

aggaaagggg ggaagagcga gcttcggccc cactaatggg ggagtgggcg gaggctggat      120

ttcccacctc ggctgcacct gggcactgga ggctgaagag gaaagtgaga atctgaagtt      180

ttgagacctc tgactggcca ggaatagctc ctggggcggg gggcaaggat gggaccatag      240

gcggaaagag tctcgcggtc ccccctgctt ctggcgcggg tccctgcgcc cggttgtgga      300

gcgtctcgcg cggggagggg gcggggggaa cggcagctcg cggtgttgtt cactcgcgcg      360

tcgagcacac ggtgggtccg gcggcgggtt ggcgccccag gcggcgttcc ctgtggcctg      420

gcgcctgggc cgctgccctg agcgggttcc gccccagagc ccgaccctcc tgggggctct      480

aggcggagtc ccgcgagccg agggggaccg gcgaccgctg ccgaagcatg aagaaggggt      540

aaggcgtgag cccccaagat ttcacggtga actggcacaa aggttaatct caagatgccg      600

ctagtgaaaa gaaacatcga tcctaggcac ttgtgccaca cagcactgcc tagaggcatt      660

aagaatgaac tggaatgtgt aaccaatatt tccttggcaa atataattag acaactaagt      720

agcctaagta aatatgctga agatatattt ggagaattat tcaatgaagc acatagtttt      780

tccttcagag tcaactcatt gcaagaacgt gtggaccgtt tatctgttag tgttacacag      840

cttgatccaa aggaagaaga attgtctttg caagatataa caatgaggaa agctttccga      900

agttctacaa ttcaagacca gcagcttttc gatcgcaaga ctttgcctat tccattacag      960

gagacgtacg atgtttgtga acagcctcca cctctcaata tactcactcc ttatagagat     1020

gatggtaaag aaggtctgaa gttttatacc aatccttcgt atttctttga tctatggaaa     1080

gaaaaaatgt tgcaagatac agaggataag aggaaggaaa agaggaagca gaagcagaaa     1140

aatctagatc gtcctcatga accagaaaaa gtgccaagag cacctcatga caggcggcga     1200

gaatggcaga agctggccca aggtccagag ctggctgaag atgatgctaa tctcttacat     1260

aagcatattg aagttgctaa tggcccagcc tctcattttg aaacaagacc tcagacatac     1320

gtggatcata tggatggatc ttactcactt tctgccttgc catttagtca gatgagtgag     1380

cttctgacta gagctgagga aagggtatta gtcagaccac atgaaccacc tccacctcca     1440

ccaatgcatg gagcaggaga tgcaaaaccg atacccacct gtatcagttc tgctacaggt     1500

ttgatagaaa atcgccctca gtcaccagct acaggcagaa cacctgtgtt tgtgagcccc     1560

actcccccac ctcctccacc acctcttcca tctgccttgt caacttcctc attaagagct     1620

tcaatgactt caactcctcc ccctccagta cctcccccac ctccacctcc agccactgct     1680

ttgcaagctc cagcagtacc accacctcca gctcctcttc agattgcccc tggagttctt     1740

cacccagctc ctcctccaat tgcacctcct ctagtacagc cctctccacc agtagctaga     1800

gctgccccag tatgtgagac tgtaccagtt catccactcc cacaaggtga agttcagggg     1860

ctgcctccac ccccaccacc gcctcctctg cctccacctg gcattcgacc atcatcacct     1920

gtcacagtta cagctcttgc tcatcctccc tctgggctac atccaactcc atctactgcc     1980

ccaggtcccc atgttccatt aatgcctcca tctcctccat cacaagttat acctgcttct     2040

gagccaaagc gccatccatc aaccctacct gtaatcagtg atgccaggag tgtgctactg     2100

gaagcaatac gaaaaggtat tcagctacgc aaagtagaag agcagcgtga acaggaagct     2160

aagcatgaac gcattgaaaa cgatgttgcc accatcctgt ctcgccgtat tgctgttgaa     2220

tatagtgatt cggaagatga ttcagaattt gatgaagtag attggttgga gtaagaaaaa     2280

tgcattgata aatattacaa aactgaatgc aaatgtcctt tgtggtgctt gttccttgaa     2340

aatgtttggt cattctagtg ttttgctttc ttttccttat aataaatgac ccttttcctc     2400

cataactttt gatttctaag gaaaatatta gcatacattt caaactaaat gttttacagt     2460

ggcttatctt ttttttcccc ctgaaaagac taatttggtc aaataaacca ctaagtatta     2520

agcatggaca gctgttgtta gagtagcaga ttcagttttt tgatatatct taattgtgta     2580

ctttgtgaat tttaatttaa agaaagcaac tgaaattgaa atcttgaggg cagctgtgtc     2640

tactaatgag ccttattcca tttcctgatg ttttaaaaga agaaacactg ccttgattat     2700

acgaatacac tcagaaagta catttagctt gtagtgttga attctcttaa aggaatgctt     2760

gaattttttc attattgttt tattgttttt atatacttgc cttatttgaa tgtttagcag     2820

tatccccttc ccacttatat attgtgtgat atgattttgc ttgcctatag gagttaaaaa     2880

cttttccatg tgaaatactc tgacttaaac atacatgtaa cttacataac tgttaagaat     2940

aacagtctga tttaataaat ggttcatttt aaaagttaaa aaaaaaa                   2987


<210>  1305
<211>  6956
<212>  DNA
<213>  homo sapiens

<400>  1305
cctgcgcggc ggcggcggcg aggcggggga gcgagtgagc gcgaggggcg ggcgcgagtg       60

actgtgtgag tcacccgtac ctggagtgcg agcgacgcag agccagcggc gcggagccgg      120

agccggagcc gagacccagc gcctgcgagc ccgagagcgc ggccggcccc aggcgccagg      180

ccccgtcgcc ctccccgtgc actcacccgt ggcccggcgc cgactcccta cccggcgccc      240

gccgcccgca gccctcccgc ctgccaggag gcggtgcggg gctcgccggg ggatgtcaca      300

gcggctcctg ggagccagca gccgccgccg ccgccgcccc cgggaaccgc gatcatgaac      360

ccccagtgcg cccgttgcgg aaaagtcgtg tatcccaccg agaaagtcaa ctgcctggat      420

aagtattggc ataaaggatg tttccattgt gaggtctgca agatggcact caacatgaac      480

aactacaaag gctatgaaaa gaagccctat tgtaatgcac actacccgaa gcagtccttc      540

accacggtgg cagatacacc tgaaaatctt cgcctgaagc agcaaagtga attgcagagt      600

caggtcaagt acaaaagaga ttttgaagaa agcaaaggga ggggcttcag catcgtcacg      660

gacactcctg agctacagag actgaagagg actcaggagc aaatcagtaa tgtaaaatac      720

catgaagatt ttgaaaaaac aaaggggaga ggctttactc ccgtcgtgga cgatcctgtg      780

acagagagag tgaggaagaa cacccaggtg gtcagcgatg ctgcctataa aggggtccac      840

cctcacatcg tggagatgga caggagacct ggaatcattg ttgcacctgt tcttcccgga      900

gcctatcagc aaagccattc ccaaggctat ggctacatgc accagaccag tgtgtcatcc      960

atgagatcaa tgcagcattc accaaatcta aggacctacc gagccatgta cgattacagt     1020

gcccaggatg aagacgaggt ctcctttaga gacggcgact acatcgtcaa cgtgcagcct     1080

attgacgatg gctggatgta cggcacagtg cagagaacag ggagaacagg aatgctccca     1140

gcgaattaca ttgagtttgt taattaatta tttctccctg ccctttgagc tttattctaa     1200

tgtatcccaa acctaatctt tttaaaagat agaagatact tttaagacaa cttggccatt     1260

attttacaat gatgtatcct tcctttgaca attagacaca caggtaccag gaagaaggaa     1320

tgacctctgg gctgaaaaca gcagcatttt cagtaattcc tacaaacaaa aatctttgtg     1380

tctggacacc tggtgctgct aattgtgttc atggtttcct ttgattggct attgaaccct     1440

tctgggaaat gtatttttgt agactttaat agagaagttg attgtccctt aaatgtagtg     1500

tgtgtttgaa acttcttagc tgtcactttg gaatcacccc aagccaattc tcttaactct     1560

gtaatgcagc caataatttc aaacccgttt tgcttttgag tcatgaggca atttccaata     1620

ttagtgaaaa ttgcccaata taataagtgt aaacagtggc agaaggacag tctggttaaa     1680

attatattga ctggtggcct tagggatcta gaaacttcta ctaaacagag aaatttcctt     1740

gttccctagg ctgactggta tctatttatt tctcatttgt accaaggcat ctcctactct     1800

ccatttatat tctatggacc caagtctatg ctcagttcca cagaatgtca ggaccaaata     1860

acttcacagc tactctgcaa agggcaaatt ataatgtcat tgatataatt tccctagtag     1920

catttaccct gttgcatgtc atgtagattc aagcttctgt aacataggca gctgcactgc     1980

gcgttcctat tattgaagca aaaagggtga ctgataccta aaagcccttt cttcctctag     2040

tcgccagctc atcagaaaaa catactttga aaagatgctt gagattttcc tgctgcatcg     2100

cactctagtt ttgaaggatt tacatcttag gaaataacat gtatactcta gtaaataagc     2160

gatttaggtg ttccattgaa cagctttgat taacttaatg ccaccattga tttcaaagtg     2220

aagaaaatgt aacagaagcc agtgaagcaa tggaagctgg agtgtgactg gaaaaatact     2280

cagcaaacaa agttaccaat tccatacaga gatgatctgg tatcttcttt tggaaaatgg     2340

tattcaaatt ctggaatgga aatctagcca ccaaaacggg ttaatcaaaa gacgtccttt     2400

tccatttttt tttgctttta ttttctaaat catttttaag ggaatgaaac aggaatgtca     2460

tcagagattt tttagtacag gcccaagagc ctgttctcta agaaagaaat tgttgccatg     2520

ttttgatttt cgaataagtg actttgcagg ctttatgcta gcccttgctg gtgggtcttg     2580

aaatttcatc cagagtctgc agtccaggtc accaagccag cggcacccgt cggcaaccct     2640

gtgtttttct gattgtgccg tttactgtga cctgcaacgg ggtggcattc acttagggtc     2700

tgacttcaca gctatgacaa aaccgaaaaa gcaaaactgc aaaaaagtac taagatgtac     2760

gggtcttggg gatatctgcc ttatatgtta tattcaagga aattaacaaa acatcctgta     2820

aaacatcgtt taaggaaacg tttactagtc caaaggccaa agctaattta tttccacttt     2880

agaaaagtta gcacatgctt ttgaaaatct gtgatttcat tttattaggc taaaagggta     2940

aataggcttt attacactga agctgcatct atatgtcact gacataaagt tgaaaaaata     3000

aatgcaggca aataactaga gacttctttt aagggggttt ggctggtttt ctctcactga     3060

aatggccagt cgtgattaaa gtgataaaac cccatatctg ttttggtata ttgtacacaa     3120

acctacaaaa ataaactgaa cttgcaatat ttttgcaaaa aaatctgtcg ttaaaactga     3180

ggataaaata cctgctcaat tttattttac taagtatata tttacatttc acccaggcag     3240

gccattttct tttgtgatta taagaaagag tagttgttga ttaaattttc agactaaata     3300

taggacaggt acaattttgg ataaatagca catttataag aaccgcaatg aaaactgact     3360

tgaaataatg cttgtaatca ggaaagtaat ttcatccacc gatttcaaaa ccagattcac     3420

tgagcataaa agtcaataca tatttgagga ataagtctcc taaaatttta agcttcacgt     3480

aataatgttt gcatagcaaa atatttctgc ttcaagcctt taggaattaa gatctgatca     3540

gaatttaact aaagggtagt tgttttacaa tgaagactaa aactgaacaa gatgttgcat     3600

gctcttgagg ccataatttg gtagtgttgg cagttgttaa taaagcttgt caggatgtta     3660

agcatctcag gagaaatatt ggaaaattat atgtataaaa ccaaagtgct atttttaaaa     3720

gcatcattta aaaaaaaatg acatgcctga acaacttttc cactttccac gtgcttccct     3780

cccacctttg gtttggcaac aggtatctcg tgcatgaagc tgacagctaa agaagatttt     3840

aaaaattgag ttaaagatga ctgtgtaaat gtccaagcac agagagcatg cacctgactt     3900

tctaaagttt gatgtgttct caagcctgac agaagcacaa ggaacagttt gatacacttt     3960

taaaaggttc tgaaaacaaa gctgtatagg gatcctctct ctcttgagca aagtatagca     4020

acagaatata ttgcttttgt tgtaagcttt tgtagtacat gtttttacta ataattcttg     4080

ttctctagaa agctttctat ttctaaccta tggcaaaatg aatccttcat gtcttcttgt     4140

tattgtttac acacttgcag tgtagcccag tttgaaatat ttatttggtt atcaactgcc     4200

catggaggag gctcttgatg atcccaggtc tcctcgacct ccatacacca cacaggcatt     4260

tgtaagcaca gtttccacaa gcaccttgta ggaatatgga taagattaga ccagcccctc     4320

tctgtccact gggtttattt cttgaagaag atgcagatct ggtttttcca atgtgccaca     4380

gtctttcctt atcctctcca tgctgagctt gacaacactc tgggaatgag gaacaagact     4440

ttttctaaaa agatagtgga agttcaaggg atgtacctcg ttttcaggtt catccatctc     4500

cagtggaatg ttttcaataa aagatgaaga aaatgtgtgt gatctttaat aacacatccc     4560

tatagaaagt ggataaaaga tataccaaaa ctgtaataca gatatataca aatataggtg     4620

cctttttgat tactcttgtt tgtctagtat gctcttggaa agaaaaccaa gcaagcaagt     4680

tgctgcctat tctatagtaa tattttatta cacatgattg atatttttgt ggtagggaag     4740

tgggatgctc ctcagatatt aaaggtgtta gctgattgta ttttatctct aaagatttag     4800

aactttagaa aatgccgact tcttccatct atttctgaaa ggttctttgt ggatttatat     4860

agagttgagc tatataaaca ttaactttag atttgggatt taaaatgcct attgtaagat     4920

agaataattg tgaggctgga ttcactacac aagatgaact tcacttcata aattaattat     4980

accttagcga tttgcttctg ataatctaaa agtggctaga ttgtggttgt tttggttaag     5040

gtgatatgga ggtgggagag cttttagtta agtaagaagc tatgtaaact gacaaggatg     5100

ctaaaataaa agtctctgaa gtattccatg ccttttggac cctttcctcg caactaactg     5160

tcaactgttg atcaaaaaag tcaaggcatt gtatgttgct tctgtggtta ttattctgtg     5220

atgcttagac tacttgaacc cataaacttg gaagaatctt tgagcaaatt ttctcagttg     5280

tctgtatgac ttcagtatat tcctgggaat gccataggat tttttgtgct tgatacatgg     5340

tatccagttt gcatagtatc acttctttgt aatccagttg ctgttaagaa tgatgtactt     5400

taaaggaaaa gagaaaactg catcacagtc ccattctcca gtgtccatgc aatgaattgc     5460

tgagcattta ggaagcagca ccaagtctat tacaggcatg gtgtgaaact tgatgtttga     5520

cctgtgatca aaattgaacc attgtacagt ttggcttctg tttgcttcaa aatatgtaga     5580

attgtggttg atgattaatt tgcgagacta actttgagag tgtaacagtt ttgaagaaaa     5640

cattgaatgt tttgcaaatg aaggggcttc acggaatgtt acaatgttac taatataatt     5700

tggcttttgt tatgcaaatt gttaacacca gctattaaaa tatattttag tagaaatgct     5760

ttaattcata tttttttcct ctacactgtg aatctttaag ccttggtgga ctagagcaac     5820

atcgtgctgc ccaaaggact aacctatgca aactagttca cattttagtg gatgtcgcag     5880

ttaatgtgta ataagacatt atttcccctg cataatgtac aacagcattg aaatgacaca     5940

ttaagcctag catcacattg tatagtacag tcactcacaa acccttcaag gctaccctaa     6000

tcattaacat taatatttgt ttaaaagcaa atcaccgatt tatctattga aactacttaa     6060

atgacggcaa accaggaatg acagatggct gtgtcagcaa tggctttaat gtgttccctg     6120

caagtggtct cctatgatag aactgcgttc tcaaatgcac tctcttcagg gtcttaatat     6180

tctgtgtttt ctctctgtat ttgtaaaaca ttataacaca ttaatttcct atctctacac     6240

atttggtttg cttaaataaa tgcaggatat aaaaaaaatg gttcacttct tggctctcac     6300

cgtggtttct tggagcatgg gttgttagat gcaagcaatg caccctaata ataccccggg     6360

tctgagattt aacatgacaa ctcacatcaa atcgcatcag aggtgtgtgc tgccttcagt     6420

gcatttacat tggtgaatca gtcaagatat tttcctcccc caaataaact tagttgtaag     6480

tgataacaat attatgcttc tccaagctca gtatctttct gattttatat caaagtaccg     6540

caacaatgca tcattgtagt taatttattt caagaataaa ttcctcatat gtcctcaata     6600

gtacaattct aattttcttc tattcataag atgaaagaaa tggtttggag catagaatag     6660

aaagtgcaca aattgagtac ataaaatggg aagcaactga tttctcagct aagaaaggct     6720

catttatcac agaacacaat tgcttttctc cccccactac gcttcccata attgaaaaag     6780

tgagtcccta tttttcacac tcatataaat ctatgcgatt tggatgctag tcttattgta     6840

ttattttgta aaactttctc tttggctcat aatccttcct aattgtaaat tgataaactt     6900

tgcggatgac atctgctcgt agaataaaca cttcttccaa aaaaaaaaaa aaaaaa         6956


<210>  1306
<211>  9231
<212>  DNA
<213>  homo sapiens

<400>  1306
cttgagtgtt agagctgagt agttttccca gaatctctaa gtccttttta tgctctttta       60

tgaatgaata gaattagtaa aagataaata aattttttct tttggatttc ttaaccagtg      120

gaaaaaatgt tgactttaaa agttcataaa atcaaatttt gcttaagaat atgttatttc      180

cacttgtgag gccagcctgg tagacctctg ggatcctttt ctgttcactc acacaccact      240

gagataagga gtgaagtgtg ggctaaatag ggctgaggct tgggcaaggg catttctgcc      300

agagcaccag agacgtcagc atctcaaggg cactgtggta tggaaaagga cgccacatga      360

gtaaatttta aaaatataaa tattttaaag ggtaaaaatg agggtccctg tatttgagga      420

tataaaagat gaaactgaag aagaaaagat aggggaagaa gaaaatgaag aagaccaggt      480

cttctataag cctgttattg aagacttaag catggaattg gccagaaaat gcacggaact      540

cattagcgat atccgttata aagaagagtt taaaaagtcc aaggataagt gtacatttgt      600

gactgacagt cctatgctaa accatgtaaa aaatatcggt gcttttattt ctgaggcaaa      660

atacaaaggc accattaaag ctgacctttc taattctctt tataagcgga tgccagccac      720

aattgacagt gtttttgcag gagaagttac acagctccag agtgaggtgg cctacaagca      780

gaaacatgat gctgccaaag gattctcaga ttatgcccac atgaaggagc cccctgaggt      840

taaacatgcc atggaggtca ataaacacca gagtaatatt tcttatagga aagacgtgca      900

ggacacccac acgtacagtg cagaacttga ccgaccagac atcaagatgg caacccagat      960

ctctaagatc ataagcaatg cagaatacaa gaaaggacaa ggaataatga ataaagagcc     1020

cgctgtaatt ggaagaccag attttgaaca tgccgtggaa gcttctaaac tttctagtca     1080

aattaaatac aaagaaaaat ttgataatga aatgaaggat aagaaacatc attacaatcc     1140

tcttgaaagt gcttctttta ggcagaatca gcttgctgct acactggcga gcaatgtgaa     1200

gtacaagaaa gacattcaaa atatgcatga tccagtttca gatctcccaa atttgttgtt     1260

tttagaccat gttttgaaag ccagcaaaat gctcagcggc cgagaatata aaaagctctt     1320

tgaggaaaac aaaggaatgt atcattttga tgcagatgct gtggaacatc tgcaccataa     1380

aggcaatgcc gtcctccaaa gtcaggtgaa atataaagaa gaatatgaga aaaataaggg     1440

aaagccaatg cttgaatttg ttgagacacc atcatatcaa gcttcaaagg aggctcaaaa     1500

gatgcaaagt gaaaaagttt acaaagagga ttttgagaag gagattaaag gaaggtcatc     1560

actggattta gacaagactc cagaattttt acatgtaaag tacatcacca accttctgag     1620

ggagaaagaa tataaaaaag atttggaaaa tgagataaaa gggaaaggaa tggaacttaa     1680

ttcagaagtt cttgatatcc aaagagcaaa gcgagcctct gaaatggcaa gtgagaaaga     1740

atacaagaaa gacctggagt caataattaa agggaaagga atgcaagctg gcactgacac     1800

ccttgaaatg cagcatgcca agaaggctgc agagatagcg agtgagaaag actataaaag     1860

agatctggag actgaaatta aagggaaagg gatgcaggtg agcacagaca ctcttgatgt     1920

ccagagagct aagaaagcat ccgagatggc cagccagaaa caatacaaga aggacttaga     1980

aaatgaaatt aaagggaaag gaatgcaagt gagcatggat atcccagata tccttcgagc     2040

caagaggaca tctgaaatct atagccagag aaagtataaa gatgaagcag agaagatgct     2100

ttctaactat tctaccatag cagatactcc tgaaattcag agaattaaga caactcaaca     2160

aaacattagt gcggtatttt ataagaaaga agtgggagct ggcactgcag tgaaagatag     2220

cccagagatc gaacgagtga agaaaaatca gcagaatatt agttcagtga aatacaaaga     2280

agagattaaa catgcaacag ccatttctga tcctccagaa ctaaagagag ttaaagaaaa     2340

ccagaagaac atcagcaatc tccagtataa agagcaaaac tacaaggcca ctccggtaag     2400

catgaccccg gagatagaga gagtgaggcg aaaccaggag cagctgagtg cggtaaaata     2460

taagggagaa cttcaacggg gaactgcaat ttctgatcca ccagagctga agagggcaaa     2520

agaaaaccag aaaaacatca gcaatgttta ttacagaggt cagctgggaa gagctaccac     2580

tttaagtgta actcctgaaa tggaaagagt gaagaagaat caagaaaata ttagctcggt     2640

aaaatatacc caggaccata aacagatgaa aggtagacca agtctgattt tagatacacc     2700

tgctatgaga catgttaaag aagcacaaaa tcatatttca atggtaaaat accatgaaga     2760

ttttgaaaaa acaaagggga gaggctttac tcccgtcgtg gacgatcctg tgacagagag     2820

agtgaggaag aacacccagg tggtcagcga tgctgcctat aaaggggtcc accctcacat     2880

cgtggagatg gacaggagac ctggaatcat tgttgacctc aaagtttggc gcacagatcc     2940

tggctccatc ttcgaccttg atcccctgga agacaatatt cagtctagaa gtctccatat     3000

gctctctgaa aaggcgagtc actataggcg acactggtct cgatcccatt ccagcagtac     3060

tttcggtaca ggtctcggag acgacaggtc agaaatctcc gagatttacc ctagcttttc     3120

atgctgcagt gaggtaacaa gaccgtctga tgaaggagca cctgttcttc ccggagccta     3180

tcagcaaagc cattcccaag gctatggcta catgcaccag accagtgtgt catccatgag     3240

atcaatgcag cattcaccaa atctaaggac ctaccgagcc atgtacgatt acagtgccca     3300

ggatgaagac gaggtctcct ttagagacgg cgactacatc gtcaacgtgc agcctattga     3360

cgatggctgg atgtacggca cagtgcagag aacagggaga acaggaatgc tcccagcgaa     3420

ttacattgag tttgttaatt aattatttct ccctgccctt tgagctttat tctaatgtat     3480

cccaaaccta atctttttaa aagatagaag atacttttaa gacaacttgg ccattatttt     3540

acaatgatgt atccttcctt tgacaattag acacacaggt accaggaaga aggaatgacc     3600

tctgggctga aaacagcagc attttcagta attcctacaa acaaaaatct ttgtgtctgg     3660

acacctggtg ctgctaattg tgttcatggt ttcctttgat tggctattga acccttctgg     3720

gaaatgtatt tttgtagact ttaatagaga agttgattgt cccttaaatg tagtgtgtgt     3780

ttgaaacttc ttagctgtca ctttggaatc accccaagcc aattctctta actctgtaat     3840

gcagccaata atttcaaacc cgttttgctt ttgagtcatg aggcaatttc caatattagt     3900

gaaaattgcc caatataata agtgtaaaca gtggcagaag gacagtctgg ttaaaattat     3960

attgactggt ggccttaggg atctagaaac ttctactaaa cagagaaatt tccttgttcc     4020

ctaggctgac tggtatctat ttatttctca tttgtaccaa ggcatctcct actctccatt     4080

tatattctat ggacccaagt ctatgctcag ttccacagaa tgtcaggacc aaataacttc     4140

acagctactc tgcaaagggc aaattataat gtcattgata taatttccct agtagcattt     4200

accctgttgc atgtcatgta gattcaagct tctgtaacat aggcagctgc actgcgcgtt     4260

cctattattg aagcaaaaag ggtgactgat acctaaaagc cctttcttcc tctagtcgcc     4320

agctcatcag aaaaacatac tttgaaaaga tgcttgagat tttcctgctg catcgcactc     4380

tagttttgaa ggatttacat cttaggaaat aacatgtata ctctagtaaa taagcgattt     4440

aggtgttcca ttgaacagct ttgattaact taatgccacc attgatttca aagtgaagaa     4500

aatgtaacag aagccagtga agcaatggaa gctggagtgt gactggaaaa atactcagca     4560

aacaaagtta ccaattccat acagagatga tctggtatct tcttttggaa aatggtattc     4620

aaattctgga atggaaatct agccaccaaa acgggttaat caaaagacgt ccttttccat     4680

ttttttttgc ttttattttc taaatcattt ttaagggaat gaaacaggaa tgtcatcaga     4740

gattttttag tacaggccca agagcctgtt ctctaagaaa gaaattgttg ccatgttttg     4800

attttcgaat aagtgacttt gcaggcttta tgctagccct tgctggtggg tcttgaaatt     4860

tcatccagag tctgcagtcc aggtcaccaa gccagcggca cccgtcggca accctgtgtt     4920

tttctgattg tgccgtttac tgtgacctgc aacggggtgg cattcactta gggtctgact     4980

tcacagctat gacaaaaccg aaaaagcaaa actgcaaaaa agtactaaga tgtacgggtc     5040

ttggggatat ctgccttata tgttatattc aaggaaatta acaaaacatc ctgtaaaaca     5100

tcgtttaagg aaacgtttac tagtccaaag gccaaagcta atttatttcc actttagaaa     5160

agttagcaca tgcttttgaa aatctgtgat ttcattttat taggctaaaa gggtaaatag     5220

gctttattac actgaagctg catctatatg tcactgacat aaagttgaaa aaataaatgc     5280

aggcaaataa ctagagactt cttttaaggg ggtttggctg gttttctctc actgaaatgg     5340

ccagtcgtga ttaaagtgat aaaaccccat atctgttttg gtatattgta cacaaaccta     5400

caaaaataaa ctgaacttgc aatatttttg caaaaaaatc tgtcgttaaa actgaggata     5460

aaatacctgc tcaattttat tttactaagt atatatttac atttcaccca ggcaggccat     5520

tttcttttgt gattataaga aagagtagtt gttgattaaa ttttcagact aaatatagga     5580

caggtacaat tttggataaa tagcacattt ataagaaccg caatgaaaac tgacttgaaa     5640

taatgcttgt aatcaggaaa gtaatttcat ccaccgattt caaaaccaga ttcactgagc     5700

ataaaagtca atacatattt gaggaataag tctcctaaaa ttttaagctt cacgtaataa     5760

tgtttgcata gcaaaatatt tctgcttcaa gcctttagga attaagatct gatcagaatt     5820

taactaaagg gtagttgttt tacaatgaag actaaaactg aacaagatgt tgcatgctct     5880

tgaggccata atttggtagt gttggcagtt gttaataaag cttgtcagga tgttaagcat     5940

ctcaggagaa atattggaaa attatatgta taaaaccaaa gtgctatttt taaaagcatc     6000

atttaaaaaa aaatgacatg cctgaacaac ttttccactt tccacgtgct tccctcccac     6060

ctttggtttg gcaacaggta tctcgtgcat gaagctgaca gctaaagaag attttaaaaa     6120

ttgagttaaa gatgactgtg taaatgtcca agcacagaga gcatgcacct gactttctaa     6180

agtttgatgt gttctcaagc ctgacagaag cacaaggaac agtttgatac acttttaaaa     6240

ggttctgaaa acaaagctgt atagggatcc tctctctctt gagcaaagta tagcaacaga     6300

atatattgct tttgttgtaa gcttttgtag tacatgtttt tactaataat tcttgttctc     6360

tagaaagctt tctatttcta acctatggca aaatgaatcc ttcatgtctt cttgttattg     6420

tttacacact tgcagtgtag cccagtttga aatatttatt tggttatcaa ctgcccatgg     6480

aggaggctct tgatgatccc aggtctcctc gacctccata caccacacag gcatttgtaa     6540

gcacagtttc cacaagcacc ttgtaggaat atggataaga ttagaccagc ccctctctgt     6600

ccactgggtt tatttcttga agaagatgca gatctggttt ttccaatgtg ccacagtctt     6660

tccttatcct ctccatgctg agcttgacaa cactctggga atgaggaaca agactttttc     6720

taaaaagata gtggaagttc aagggatgta cctcgttttc aggttcatcc atctccagtg     6780

gaatgttttc aataaaagat gaagaaaatg tgtgtgatct ttaataacac atccctatag     6840

aaagtggata aaagatatac caaaactgta atacagatat atacaaatat aggtgccttt     6900

ttgattactc ttgtttgtct agtatgctct tggaaagaaa accaagcaag caagttgctg     6960

cctattctat agtaatattt tattacacat gattgatatt tttgtggtag ggaagtggga     7020

tgctcctcag atattaaagg tgttagctga ttgtatttta tctctaaaga tttagaactt     7080

tagaaaatgc cgacttcttc catctatttc tgaaaggttc tttgtggatt tatatagagt     7140

tgagctatat aaacattaac tttagatttg ggatttaaaa tgcctattgt aagatagaat     7200

aattgtgagg ctggattcac tacacaagat gaacttcact tcataaatta attatacctt     7260

agcgatttgc ttctgataat ctaaaagtgg ctagattgtg gttgttttgg ttaaggtgat     7320

atggaggtgg gagagctttt agttaagtaa gaagctatgt aaactgacaa ggatgctaaa     7380

ataaaagtct ctgaagtatt ccatgccttt tggacccttt cctcgcaact aactgtcaac     7440

tgttgatcaa aaaagtcaag gcattgtatg ttgcttctgt ggttattatt ctgtgatgct     7500

tagactactt gaacccataa acttggaaga atctttgagc aaattttctc agttgtctgt     7560

atgacttcag tatattcctg ggaatgccat aggatttttt gtgcttgata catggtatcc     7620

agtttgcata gtatcacttc tttgtaatcc agttgctgtt aagaatgatg tactttaaag     7680

gaaaagagaa aactgcatca cagtcccatt ctccagtgtc catgcaatga attgctgagc     7740

atttaggaag cagcaccaag tctattacag gcatggtgtg aaacttgatg tttgacctgt     7800

gatcaaaatt gaaccattgt acagtttggc ttctgtttgc ttcaaaatat gtagaattgt     7860

ggttgatgat taatttgcga gactaacttt gagagtgtaa cagttttgaa gaaaacattg     7920

aatgttttgc aaatgaaggg gcttcacgga atgttacaat gttactaata taatttggct     7980

tttgttatgc aaattgttaa caccagctat taaaatatat tttagtagaa atgctttaat     8040

tcatattttt ttcctctaca ctgtgaatct ttaagccttg gtggactaga gcaacatcgt     8100

gctgcccaaa ggactaacct atgcaaacta gttcacattt tagtggatgt cgcagttaat     8160

gtgtaataag acattatttc ccctgcataa tgtacaacag cattgaaatg acacattaag     8220

cctagcatca cattgtatag tacagtcact cacaaaccct tcaaggctac cctaatcatt     8280

aacattaata tttgtttaaa agcaaatcac cgatttatct attgaaacta cttaaatgac     8340

ggcaaaccag gaatgacaga tggctgtgtc agcaatggct ttaatgtgtt ccctgcaagt     8400

ggtctcctat gatagaactg cgttctcaaa tgcactctct tcagggtctt aatattctgt     8460

gttttctctc tgtatttgta aaacattata acacattaat ttcctatctc tacacatttg     8520

gtttgcttaa ataaatgcag gatataaaaa aaatggttca cttcttggct ctcaccgtgg     8580

tttcttggag catgggttgt tagatgcaag caatgcaccc taataatacc ccgggtctga     8640

gatttaacat gacaactcac atcaaatcgc atcagaggtg tgtgctgcct tcagtgcatt     8700

tacattggtg aatcagtcaa gatattttcc tcccccaaat aaacttagtt gtaagtgata     8760

acaatattat gcttctccaa gctcagtatc tttctgattt tatatcaaag taccgcaaca     8820

atgcatcatt gtagttaatt tatttcaaga ataaattcct catatgtcct caatagtaca     8880

attctaattt tcttctattc ataagatgaa agaaatggtt tggagcatag aatagaaagt     8940

gcacaaattg agtacataaa atgggaagca actgatttct cagctaagaa aggctcattt     9000

atcacagaac acaattgctt ttctcccccc actacgcttc ccataattga aaaagtgagt     9060

ccctattttt cacactcata taaatctatg cgatttggat gctagtctta ttgtattatt     9120

ttgtaaaact ttctctttgg ctcataatcc ttcctaattg taaattgata aactttgcgg     9180

atgacatctg ctcgtagaat aaacacttct tccaaaaaaa aaaaaaaaaa a              9231


<210>  1307
<211>  6956
<212>  DNA
<213>  homo sapiens

<400>  1307
cctgcgcggc ggcggcggcg aggcggggga gcgagtgagc gcgaggggcg ggcgcgagtg       60

actgtgtgag tcacccgtac ctggagtgcg agcgacgcag agccagcggc gcggagccgg      120

agccggagcc gagacccagc gcctgcgagc ccgagagcgc ggccggcccc aggcgccagg      180

ccccgtcgcc ctccccgtgc actcacccgt ggcccggcgc cgactcccta cccggcgccc      240

gccgcccgca gccctcccgc ctgccaggag gcggtgcggg gctcgccggg ggatgtcaca      300

gcggctcctg ggagccagca gccgccgccg ccgccgcccc cgggaaccgc gatcatgaac      360

ccccagtgcg cccgttgcgg aaaagtcgtg tatcccaccg agaaagtcaa ctgcctggat      420

aagtattggc ataaaggatg tttccattgt gaggtctgca agatggcact caacatgaac      480

aactacaaag gctatgaaaa gaagccctat tgtaatgcac actacccgaa gcagtccttc      540

accacggtgg cagatacacc tgaaaatctt cgcctgaagc agcaaagtga attgcagagt      600

caggtcaagt acaaaagaga ttttgaagaa agcaaaggga ggggcttcag catcgtcacg      660

gacactcctg agctacagag actgaagagg actcaggagc aaatcagtaa tgtaaaatac      720

catgaagatt ttgaaaaaac aaaggggaga ggctttactc ccgtcgtgga cgatcctgtg      780

acagagagag tgaggaagaa cacccaggtg gtcagcgatg ctgcctataa aggggtccac      840

cctcacatcg tggagatgga caggagacct ggaatcattg ttgcacctgt tcttcccgga      900

gcctatcagc aaagccattc ccaaggctat ggctacatgc accagaccag tgtgtcatcc      960

atgagatcaa tgcagcattc accaaatcta aggacctacc gagccatgta cgattacagt     1020

gcccaggatg aagacgaggt ctcctttaga gacggcgact acatcgtcaa cgtgcagcct     1080

attgacgatg gctggatgta cggcacagtg cagagaacag ggagaacagg aatgctccca     1140

gcgaattaca ttgagtttgt taattaatta tttctccctg ccctttgagc tttattctaa     1200

tgtatcccaa acctaatctt tttaaaagat agaagatact tttaagacaa cttggccatt     1260

attttacaat gatgtatcct tcctttgaca attagacaca caggtaccag gaagaaggaa     1320

tgacctctgg gctgaaaaca gcagcatttt cagtaattcc tacaaacaaa aatctttgtg     1380

tctggacacc tggtgctgct aattgtgttc atggtttcct ttgattggct attgaaccct     1440

tctgggaaat gtatttttgt agactttaat agagaagttg attgtccctt aaatgtagtg     1500

tgtgtttgaa acttcttagc tgtcactttg gaatcacccc aagccaattc tcttaactct     1560

gtaatgcagc caataatttc aaacccgttt tgcttttgag tcatgaggca atttccaata     1620

ttagtgaaaa ttgcccaata taataagtgt aaacagtggc agaaggacag tctggttaaa     1680

attatattga ctggtggcct tagggatcta gaaacttcta ctaaacagag aaatttcctt     1740

gttccctagg ctgactggta tctatttatt tctcatttgt accaaggcat ctcctactct     1800

ccatttatat tctatggacc caagtctatg ctcagttcca cagaatgtca ggaccaaata     1860

acttcacagc tactctgcaa agggcaaatt ataatgtcat tgatataatt tccctagtag     1920

catttaccct gttgcatgtc atgtagattc aagcttctgt aacataggca gctgcactgc     1980

gcgttcctat tattgaagca aaaagggtga ctgataccta aaagcccttt cttcctctag     2040

tcgccagctc atcagaaaaa catactttga aaagatgctt gagattttcc tgctgcatcg     2100

cactctagtt ttgaaggatt tacatcttag gaaataacat gtatactcta gtaaataagc     2160

gatttaggtg ttccattgaa cagctttgat taacttaatg ccaccattga tttcaaagtg     2220

aagaaaatgt aacagaagcc agtgaagcaa tggaagctgg agtgtgactg gaaaaatact     2280

cagcaaacaa agttaccaat tccatacaga gatgatctgg tatcttcttt tggaaaatgg     2340

tattcaaatt ctggaatgga aatctagcca ccaaaacggg ttaatcaaaa gacgtccttt     2400

tccatttttt tttgctttta ttttctaaat catttttaag ggaatgaaac aggaatgtca     2460

tcagagattt tttagtacag gcccaagagc ctgttctcta agaaagaaat tgttgccatg     2520

ttttgatttt cgaataagtg actttgcagg ctttatgcta gcccttgctg gtgggtcttg     2580

aaatttcatc cagagtctgc agtccaggtc accaagccag cggcacccgt cggcaaccct     2640

gtgtttttct gattgtgccg tttactgtga cctgcaacgg ggtggcattc acttagggtc     2700

tgacttcaca gctatgacaa aaccgaaaaa gcaaaactgc aaaaaagtac taagatgtac     2760

gggtcttggg gatatctgcc ttatatgtta tattcaagga aattaacaaa acatcctgta     2820

aaacatcgtt taaggaaacg tttactagtc caaaggccaa agctaattta tttccacttt     2880

agaaaagtta gcacatgctt ttgaaaatct gtgatttcat tttattaggc taaaagggta     2940

aataggcttt attacactga agctgcatct atatgtcact gacataaagt tgaaaaaata     3000

aatgcaggca aataactaga gacttctttt aagggggttt ggctggtttt ctctcactga     3060

aatggccagt cgtgattaaa gtgataaaac cccatatctg ttttggtata ttgtacacaa     3120

acctacaaaa ataaactgaa cttgcaatat ttttgcaaaa aaatctgtcg ttaaaactga     3180

ggataaaata cctgctcaat tttattttac taagtatata tttacatttc acccaggcag     3240

gccattttct tttgtgatta taagaaagag tagttgttga ttaaattttc agactaaata     3300

taggacaggt acaattttgg ataaatagca catttataag aaccgcaatg aaaactgact     3360

tgaaataatg cttgtaatca ggaaagtaat ttcatccacc gatttcaaaa ccagattcac     3420

tgagcataaa agtcaataca tatttgagga ataagtctcc taaaatttta agcttcacgt     3480

aataatgttt gcatagcaaa atatttctgc ttcaagcctt taggaattaa gatctgatca     3540

gaatttaact aaagggtagt tgttttacaa tgaagactaa aactgaacaa gatgttgcat     3600

gctcttgagg ccataatttg gtagtgttgg cagttgttaa taaagcttgt caggatgtta     3660

agcatctcag gagaaatatt ggaaaattat atgtataaaa ccaaagtgct atttttaaaa     3720

gcatcattta aaaaaaaatg acatgcctga acaacttttc cactttccac gtgcttccct     3780

cccacctttg gtttggcaac aggtatctcg tgcatgaagc tgacagctaa agaagatttt     3840

aaaaattgag ttaaagatga ctgtgtaaat gtccaagcac agagagcatg cacctgactt     3900

tctaaagttt gatgtgttct caagcctgac agaagcacaa ggaacagttt gatacacttt     3960

taaaaggttc tgaaaacaaa gctgtatagg gatcctctct ctcttgagca aagtatagca     4020

acagaatata ttgcttttgt tgtaagcttt tgtagtacat gtttttacta ataattcttg     4080

ttctctagaa agctttctat ttctaaccta tggcaaaatg aatccttcat gtcttcttgt     4140

tattgtttac acacttgcag tgtagcccag tttgaaatat ttatttggtt atcaactgcc     4200

catggaggag gctcttgatg atcccaggtc tcctcgacct ccatacacca cacaggcatt     4260

tgtaagcaca gtttccacaa gcaccttgta ggaatatgga taagattaga ccagcccctc     4320

tctgtccact gggtttattt cttgaagaag atgcagatct ggtttttcca atgtgccaca     4380

gtctttcctt atcctctcca tgctgagctt gacaacactc tgggaatgag gaacaagact     4440

ttttctaaaa agatagtgga agttcaaggg atgtacctcg ttttcaggtt catccatctc     4500

cagtggaatg ttttcaataa aagatgaaga aaatgtgtgt gatctttaat aacacatccc     4560

tatagaaagt ggataaaaga tataccaaaa ctgtaataca gatatataca aatataggtg     4620

cctttttgat tactcttgtt tgtctagtat gctcttggaa agaaaaccaa gcaagcaagt     4680

tgctgcctat tctatagtaa tattttatta cacatgattg atatttttgt ggtagggaag     4740

tgggatgctc ctcagatatt aaaggtgtta gctgattgta ttttatctct aaagatttag     4800

aactttagaa aatgccgact tcttccatct atttctgaaa ggttctttgt ggatttatat     4860

agagttgagc tatataaaca ttaactttag atttgggatt taaaatgcct attgtaagat     4920

agaataattg tgaggctgga ttcactacac aagatgaact tcacttcata aattaattat     4980

accttagcga tttgcttctg ataatctaaa agtggctaga ttgtggttgt tttggttaag     5040

gtgatatgga ggtgggagag cttttagtta agtaagaagc tatgtaaact gacaaggatg     5100

ctaaaataaa agtctctgaa gtattccatg ccttttggac cctttcctcg caactaactg     5160

tcaactgttg atcaaaaaag tcaaggcatt gtatgttgct tctgtggtta ttattctgtg     5220

atgcttagac tacttgaacc cataaacttg gaagaatctt tgagcaaatt ttctcagttg     5280

tctgtatgac ttcagtatat tcctgggaat gccataggat tttttgtgct tgatacatgg     5340

tatccagttt gcatagtatc acttctttgt aatccagttg ctgttaagaa tgatgtactt     5400

taaaggaaaa gagaaaactg catcacagtc ccattctcca gtgtccatgc aatgaattgc     5460

tgagcattta ggaagcagca ccaagtctat tacaggcatg gtgtgaaact tgatgtttga     5520

cctgtgatca aaattgaacc attgtacagt ttggcttctg tttgcttcaa aatatgtaga     5580

attgtggttg atgattaatt tgcgagacta actttgagag tgtaacagtt ttgaagaaaa     5640

cattgaatgt tttgcaaatg aaggggcttc acggaatgtt acaatgttac taatataatt     5700

tggcttttgt tatgcaaatt gttaacacca gctattaaaa tatattttag tagaaatgct     5760

ttaattcata tttttttcct ctacactgtg aatctttaag ccttggtgga ctagagcaac     5820

atcgtgctgc ccaaaggact aacctatgca aactagttca cattttagtg gatgtcgcag     5880

ttaatgtgta ataagacatt atttcccctg cataatgtac aacagcattg aaatgacaca     5940

ttaagcctag catcacattg tatagtacag tcactcacaa acccttcaag gctaccctaa     6000

tcattaacat taatatttgt ttaaaagcaa atcaccgatt tatctattga aactacttaa     6060

atgacggcaa accaggaatg acagatggct gtgtcagcaa tggctttaat gtgttccctg     6120

caagtggtct cctatgatag aactgcgttc tcaaatgcac tctcttcagg gtcttaatat     6180

tctgtgtttt ctctctgtat ttgtaaaaca ttataacaca ttaatttcct atctctacac     6240

atttggtttg cttaaataaa tgcaggatat aaaaaaaatg gttcacttct tggctctcac     6300

cgtggtttct tggagcatgg gttgttagat gcaagcaatg caccctaata ataccccggg     6360

tctgagattt aacatgacaa ctcacatcaa atcgcatcag aggtgtgtgc tgccttcagt     6420

gcatttacat tggtgaatca gtcaagatat tttcctcccc caaataaact tagttgtaag     6480

tgataacaat attatgcttc tccaagctca gtatctttct gattttatat caaagtaccg     6540

caacaatgca tcattgtagt taatttattt caagaataaa ttcctcatat gtcctcaata     6600

gtacaattct aattttcttc tattcataag atgaaagaaa tggtttggag catagaatag     6660

aaagtgcaca aattgagtac ataaaatggg aagcaactga tttctcagct aagaaaggct     6720

catttatcac agaacacaat tgcttttctc cccccactac gcttcccata attgaaaaag     6780

tgagtcccta tttttcacac tcatataaat ctatgcgatt tggatgctag tcttattgta     6840

ttattttgta aaactttctc tttggctcat aatccttcct aattgtaaat tgataaactt     6900

tgcggatgac atctgctcgt agaataaaca cttcttccaa aaaaaaaaaa aaaaaa         6956


<210>  1308
<211>  9231
<212>  DNA
<213>  homo sapiens

<400>  1308
cttgagtgtt agagctgagt agttttccca gaatctctaa gtccttttta tgctctttta       60

tgaatgaata gaattagtaa aagataaata aattttttct tttggatttc ttaaccagtg      120

gaaaaaatgt tgactttaaa agttcataaa atcaaatttt gcttaagaat atgttatttc      180

cacttgtgag gccagcctgg tagacctctg ggatcctttt ctgttcactc acacaccact      240

gagataagga gtgaagtgtg ggctaaatag ggctgaggct tgggcaaggg catttctgcc      300

agagcaccag agacgtcagc atctcaaggg cactgtggta tggaaaagga cgccacatga      360

gtaaatttta aaaatataaa tattttaaag ggtaaaaatg agggtccctg tatttgagga      420

tataaaagat gaaactgaag aagaaaagat aggggaagaa gaaaatgaag aagaccaggt      480

cttctataag cctgttattg aagacttaag catggaattg gccagaaaat gcacggaact      540

cattagcgat atccgttata aagaagagtt taaaaagtcc aaggataagt gtacatttgt      600

gactgacagt cctatgctaa accatgtaaa aaatatcggt gcttttattt ctgaggcaaa      660

atacaaaggc accattaaag ctgacctttc taattctctt tataagcgga tgccagccac      720

aattgacagt gtttttgcag gagaagttac acagctccag agtgaggtgg cctacaagca      780

gaaacatgat gctgccaaag gattctcaga ttatgcccac atgaaggagc cccctgaggt      840

taaacatgcc atggaggtca ataaacacca gagtaatatt tcttatagga aagacgtgca      900

ggacacccac acgtacagtg cagaacttga ccgaccagac atcaagatgg caacccagat      960

ctctaagatc ataagcaatg cagaatacaa gaaaggacaa ggaataatga ataaagagcc     1020

cgctgtaatt ggaagaccag attttgaaca tgccgtggaa gcttctaaac tttctagtca     1080

aattaaatac aaagaaaaat ttgataatga aatgaaggat aagaaacatc attacaatcc     1140

tcttgaaagt gcttctttta ggcagaatca gcttgctgct acactggcga gcaatgtgaa     1200

gtacaagaaa gacattcaaa atatgcatga tccagtttca gatctcccaa atttgttgtt     1260

tttagaccat gttttgaaag ccagcaaaat gctcagcggc cgagaatata aaaagctctt     1320

tgaggaaaac aaaggaatgt atcattttga tgcagatgct gtggaacatc tgcaccataa     1380

aggcaatgcc gtcctccaaa gtcaggtgaa atataaagaa gaatatgaga aaaataaggg     1440

aaagccaatg cttgaatttg ttgagacacc atcatatcaa gcttcaaagg aggctcaaaa     1500

gatgcaaagt gaaaaagttt acaaagagga ttttgagaag gagattaaag gaaggtcatc     1560

actggattta gacaagactc cagaattttt acatgtaaag tacatcacca accttctgag     1620

ggagaaagaa tataaaaaag atttggaaaa tgagataaaa gggaaaggaa tggaacttaa     1680

ttcagaagtt cttgatatcc aaagagcaaa gcgagcctct gaaatggcaa gtgagaaaga     1740

atacaagaaa gacctggagt caataattaa agggaaagga atgcaagctg gcactgacac     1800

ccttgaaatg cagcatgcca agaaggctgc agagatagcg agtgagaaag actataaaag     1860

agatctggag actgaaatta aagggaaagg gatgcaggtg agcacagaca ctcttgatgt     1920

ccagagagct aagaaagcat ccgagatggc cagccagaaa caatacaaga aggacttaga     1980

aaatgaaatt aaagggaaag gaatgcaagt gagcatggat atcccagata tccttcgagc     2040

caagaggaca tctgaaatct atagccagag aaagtataaa gatgaagcag agaagatgct     2100

ttctaactat tctaccatag cagatactcc tgaaattcag agaattaaga caactcaaca     2160

aaacattagt gcggtatttt ataagaaaga agtgggagct ggcactgcag tgaaagatag     2220

cccagagatc gaacgagtga agaaaaatca gcagaatatt agttcagtga aatacaaaga     2280

agagattaaa catgcaacag ccatttctga tcctccagaa ctaaagagag ttaaagaaaa     2340

ccagaagaac atcagcaatc tccagtataa agagcaaaac tacaaggcca ctccggtaag     2400

catgaccccg gagatagaga gagtgaggcg aaaccaggag cagctgagtg cggtaaaata     2460

taagggagaa cttcaacggg gaactgcaat ttctgatcca ccagagctga agagggcaaa     2520

agaaaaccag aaaaacatca gcaatgttta ttacagaggt cagctgggaa gagctaccac     2580

tttaagtgta actcctgaaa tggaaagagt gaagaagaat caagaaaata ttagctcggt     2640

aaaatatacc caggaccata aacagatgaa aggtagacca agtctgattt tagatacacc     2700

tgctatgaga catgttaaag aagcacaaaa tcatatttca atggtaaaat accatgaaga     2760

ttttgaaaaa acaaagggga gaggctttac tcccgtcgtg gacgatcctg tgacagagag     2820

agtgaggaag aacacccagg tggtcagcga tgctgcctat aaaggggtcc accctcacat     2880

cgtggagatg gacaggagac ctggaatcat tgttgacctc aaagtttggc gcacagatcc     2940

tggctccatc ttcgaccttg atcccctgga agacaatatt cagtctagaa gtctccatat     3000

gctctctgaa aaggcgagtc actataggcg acactggtct cgatcccatt ccagcagtac     3060

tttcggtaca ggtctcggag acgacaggtc agaaatctcc gagatttacc ctagcttttc     3120

atgctgcagt gaggtaacaa gaccgtctga tgaaggagca cctgttcttc ccggagccta     3180

tcagcaaagc cattcccaag gctatggcta catgcaccag accagtgtgt catccatgag     3240

atcaatgcag cattcaccaa atctaaggac ctaccgagcc atgtacgatt acagtgccca     3300

ggatgaagac gaggtctcct ttagagacgg cgactacatc gtcaacgtgc agcctattga     3360

cgatggctgg atgtacggca cagtgcagag aacagggaga acaggaatgc tcccagcgaa     3420

ttacattgag tttgttaatt aattatttct ccctgccctt tgagctttat tctaatgtat     3480

cccaaaccta atctttttaa aagatagaag atacttttaa gacaacttgg ccattatttt     3540

acaatgatgt atccttcctt tgacaattag acacacaggt accaggaaga aggaatgacc     3600

tctgggctga aaacagcagc attttcagta attcctacaa acaaaaatct ttgtgtctgg     3660

acacctggtg ctgctaattg tgttcatggt ttcctttgat tggctattga acccttctgg     3720

gaaatgtatt tttgtagact ttaatagaga agttgattgt cccttaaatg tagtgtgtgt     3780

ttgaaacttc ttagctgtca ctttggaatc accccaagcc aattctctta actctgtaat     3840

gcagccaata atttcaaacc cgttttgctt ttgagtcatg aggcaatttc caatattagt     3900

gaaaattgcc caatataata agtgtaaaca gtggcagaag gacagtctgg ttaaaattat     3960

attgactggt ggccttaggg atctagaaac ttctactaaa cagagaaatt tccttgttcc     4020

ctaggctgac tggtatctat ttatttctca tttgtaccaa ggcatctcct actctccatt     4080

tatattctat ggacccaagt ctatgctcag ttccacagaa tgtcaggacc aaataacttc     4140

acagctactc tgcaaagggc aaattataat gtcattgata taatttccct agtagcattt     4200

accctgttgc atgtcatgta gattcaagct tctgtaacat aggcagctgc actgcgcgtt     4260

cctattattg aagcaaaaag ggtgactgat acctaaaagc cctttcttcc tctagtcgcc     4320

agctcatcag aaaaacatac tttgaaaaga tgcttgagat tttcctgctg catcgcactc     4380

tagttttgaa ggatttacat cttaggaaat aacatgtata ctctagtaaa taagcgattt     4440

aggtgttcca ttgaacagct ttgattaact taatgccacc attgatttca aagtgaagaa     4500

aatgtaacag aagccagtga agcaatggaa gctggagtgt gactggaaaa atactcagca     4560

aacaaagtta ccaattccat acagagatga tctggtatct tcttttggaa aatggtattc     4620

aaattctgga atggaaatct agccaccaaa acgggttaat caaaagacgt ccttttccat     4680

ttttttttgc ttttattttc taaatcattt ttaagggaat gaaacaggaa tgtcatcaga     4740

gattttttag tacaggccca agagcctgtt ctctaagaaa gaaattgttg ccatgttttg     4800

attttcgaat aagtgacttt gcaggcttta tgctagccct tgctggtggg tcttgaaatt     4860

tcatccagag tctgcagtcc aggtcaccaa gccagcggca cccgtcggca accctgtgtt     4920

tttctgattg tgccgtttac tgtgacctgc aacggggtgg cattcactta gggtctgact     4980

tcacagctat gacaaaaccg aaaaagcaaa actgcaaaaa agtactaaga tgtacgggtc     5040

ttggggatat ctgccttata tgttatattc aaggaaatta acaaaacatc ctgtaaaaca     5100

tcgtttaagg aaacgtttac tagtccaaag gccaaagcta atttatttcc actttagaaa     5160

agttagcaca tgcttttgaa aatctgtgat ttcattttat taggctaaaa gggtaaatag     5220

gctttattac actgaagctg catctatatg tcactgacat aaagttgaaa aaataaatgc     5280

aggcaaataa ctagagactt cttttaaggg ggtttggctg gttttctctc actgaaatgg     5340

ccagtcgtga ttaaagtgat aaaaccccat atctgttttg gtatattgta cacaaaccta     5400

caaaaataaa ctgaacttgc aatatttttg caaaaaaatc tgtcgttaaa actgaggata     5460

aaatacctgc tcaattttat tttactaagt atatatttac atttcaccca ggcaggccat     5520

tttcttttgt gattataaga aagagtagtt gttgattaaa ttttcagact aaatatagga     5580

caggtacaat tttggataaa tagcacattt ataagaaccg caatgaaaac tgacttgaaa     5640

taatgcttgt aatcaggaaa gtaatttcat ccaccgattt caaaaccaga ttcactgagc     5700

ataaaagtca atacatattt gaggaataag tctcctaaaa ttttaagctt cacgtaataa     5760

tgtttgcata gcaaaatatt tctgcttcaa gcctttagga attaagatct gatcagaatt     5820

taactaaagg gtagttgttt tacaatgaag actaaaactg aacaagatgt tgcatgctct     5880

tgaggccata atttggtagt gttggcagtt gttaataaag cttgtcagga tgttaagcat     5940

ctcaggagaa atattggaaa attatatgta taaaaccaaa gtgctatttt taaaagcatc     6000

atttaaaaaa aaatgacatg cctgaacaac ttttccactt tccacgtgct tccctcccac     6060

ctttggtttg gcaacaggta tctcgtgcat gaagctgaca gctaaagaag attttaaaaa     6120

ttgagttaaa gatgactgtg taaatgtcca agcacagaga gcatgcacct gactttctaa     6180

agtttgatgt gttctcaagc ctgacagaag cacaaggaac agtttgatac acttttaaaa     6240

ggttctgaaa acaaagctgt atagggatcc tctctctctt gagcaaagta tagcaacaga     6300

atatattgct tttgttgtaa gcttttgtag tacatgtttt tactaataat tcttgttctc     6360

tagaaagctt tctatttcta acctatggca aaatgaatcc ttcatgtctt cttgttattg     6420

tttacacact tgcagtgtag cccagtttga aatatttatt tggttatcaa ctgcccatgg     6480

aggaggctct tgatgatccc aggtctcctc gacctccata caccacacag gcatttgtaa     6540

gcacagtttc cacaagcacc ttgtaggaat atggataaga ttagaccagc ccctctctgt     6600

ccactgggtt tatttcttga agaagatgca gatctggttt ttccaatgtg ccacagtctt     6660

tccttatcct ctccatgctg agcttgacaa cactctggga atgaggaaca agactttttc     6720

taaaaagata gtggaagttc aagggatgta cctcgttttc aggttcatcc atctccagtg     6780

gaatgttttc aataaaagat gaagaaaatg tgtgtgatct ttaataacac atccctatag     6840

aaagtggata aaagatatac caaaactgta atacagatat atacaaatat aggtgccttt     6900

ttgattactc ttgtttgtct agtatgctct tggaaagaaa accaagcaag caagttgctg     6960

cctattctat agtaatattt tattacacat gattgatatt tttgtggtag ggaagtggga     7020

tgctcctcag atattaaagg tgttagctga ttgtatttta tctctaaaga tttagaactt     7080

tagaaaatgc cgacttcttc catctatttc tgaaaggttc tttgtggatt tatatagagt     7140

tgagctatat aaacattaac tttagatttg ggatttaaaa tgcctattgt aagatagaat     7200

aattgtgagg ctggattcac tacacaagat gaacttcact tcataaatta attatacctt     7260

agcgatttgc ttctgataat ctaaaagtgg ctagattgtg gttgttttgg ttaaggtgat     7320

atggaggtgg gagagctttt agttaagtaa gaagctatgt aaactgacaa ggatgctaaa     7380

ataaaagtct ctgaagtatt ccatgccttt tggacccttt cctcgcaact aactgtcaac     7440

tgttgatcaa aaaagtcaag gcattgtatg ttgcttctgt ggttattatt ctgtgatgct     7500

tagactactt gaacccataa acttggaaga atctttgagc aaattttctc agttgtctgt     7560

atgacttcag tatattcctg ggaatgccat aggatttttt gtgcttgata catggtatcc     7620

agtttgcata gtatcacttc tttgtaatcc agttgctgtt aagaatgatg tactttaaag     7680

gaaaagagaa aactgcatca cagtcccatt ctccagtgtc catgcaatga attgctgagc     7740

atttaggaag cagcaccaag tctattacag gcatggtgtg aaacttgatg tttgacctgt     7800

gatcaaaatt gaaccattgt acagtttggc ttctgtttgc ttcaaaatat gtagaattgt     7860

ggttgatgat taatttgcga gactaacttt gagagtgtaa cagttttgaa gaaaacattg     7920

aatgttttgc aaatgaaggg gcttcacgga atgttacaat gttactaata taatttggct     7980

tttgttatgc aaattgttaa caccagctat taaaatatat tttagtagaa atgctttaat     8040

tcatattttt ttcctctaca ctgtgaatct ttaagccttg gtggactaga gcaacatcgt     8100

gctgcccaaa ggactaacct atgcaaacta gttcacattt tagtggatgt cgcagttaat     8160

gtgtaataag acattatttc ccctgcataa tgtacaacag cattgaaatg acacattaag     8220

cctagcatca cattgtatag tacagtcact cacaaaccct tcaaggctac cctaatcatt     8280

aacattaata tttgtttaaa agcaaatcac cgatttatct attgaaacta cttaaatgac     8340

ggcaaaccag gaatgacaga tggctgtgtc agcaatggct ttaatgtgtt ccctgcaagt     8400

ggtctcctat gatagaactg cgttctcaaa tgcactctct tcagggtctt aatattctgt     8460

gttttctctc tgtatttgta aaacattata acacattaat ttcctatctc tacacatttg     8520

gtttgcttaa ataaatgcag gatataaaaa aaatggttca cttcttggct ctcaccgtgg     8580

tttcttggag catgggttgt tagatgcaag caatgcaccc taataatacc ccgggtctga     8640

gatttaacat gacaactcac atcaaatcgc atcagaggtg tgtgctgcct tcagtgcatt     8700

tacattggtg aatcagtcaa gatattttcc tcccccaaat aaacttagtt gtaagtgata     8760

acaatattat gcttctccaa gctcagtatc tttctgattt tatatcaaag taccgcaaca     8820

atgcatcatt gtagttaatt tatttcaaga ataaattcct catatgtcct caatagtaca     8880

attctaattt tcttctattc ataagatgaa agaaatggtt tggagcatag aatagaaagt     8940

gcacaaattg agtacataaa atgggaagca actgatttct cagctaagaa aggctcattt     9000

atcacagaac acaattgctt ttctcccccc actacgcttc ccataattga aaaagtgagt     9060

ccctattttt cacactcata taaatctatg cgatttggat gctagtctta ttgtattatt     9120

ttgtaaaact ttctctttgg ctcataatcc ttcctaattg taaattgata aactttgcgg     9180

atgacatctg ctcgtagaat aaacacttct tccaaaaaaa aaaaaaaaaa a              9231


<210>  1309
<211>  8388
<212>  DNA
<213>  homo sapiens

<400>  1309
gccatttcca gagaggaaca accgtgtaga ctgctttcct gggagtcaag ttaaaacttc       60

tctcctgtga ccttgtcacc cggcagtgga aagttaccct tggctgcagc cacgacttcc      120

gcatactctt cagaacttgc tctgcccttg agttttccag ctttccttta atgcactaaa      180

cctttaatat tgtattctcc taaatgagac gtctcgcatt tgagcaggta acactcggga      240

gagtcccgta ttctcagagt aaaagttgtt tctggaattg atctcgccaa aaaggacatc      300

tttggagcca gtgatccgta tgtgaaactt tcattgtacg tagcggatga gaatagagaa      360

cttgctttgg tccagacaaa aacaattaaa aagacactga acccaaaatg gaatgaagaa      420

ttttatttca gggtaaaccc atctaatcac agactcctat ttgaagtatt tgacgaaaat      480

agactgacac gagacgactt cctgggccag gtggacgtgc cccttagtca ccttccgaca      540

gaagatccaa ccatggagcg accctataca tttaaggact ttctcctcag accaagaagt      600

cataagtctc gagttaaggg atttttgcga ttgaaaatgg cctatatgcc aaaaaatgga      660

ggtcaagatg aagaaaacag tgaccagagg gatgacatgg agcatggatg ggaagttgtt      720

gactcaaatg actcggcttc tcagcaccaa gaggaacttc ctcctcctcc tctgcctccc      780

gggtgggaag aaaaagtgga caatttaggc cgaacttact atgtcaacca caacaaccgg      840

accactcagt ggcacagacc aagcctgatg gacgtgtcct cggagtcgga caataacatc      900

agacagatca accaggaggc agcacaccgg cgcttccgct cccgcaggca catcagcgaa      960

gacttggagc ccgagccctc ggagggcggg gatgtccccg agccttggga gaccatttca     1020

gaggaagtga atatcgctgg agactctctc ggtctggctc tgcccccacc accggcctcc     1080

ccaggatctc ggaccagccc tcaggagctg tcagaggaac taagcagaag gcttcagatc     1140

actccagact ccaatgggga acagttcagc tctttgattc aaagagaacc ctcctcaagg     1200

ttgaggtcat gcagtgtcac cgacgcagtt gcagaacagg gccatctacc accgcccagt     1260

gccccagctg ggagagcgcg ttcatcaact gtcacgggtg gtgaggaacc aacgccatca     1320

gtggcctatg tacataccac gccgggtctg ccttcaggct gggaagaaag aaaagatgct     1380

aaggggcgca catactatgt caatcataac aatcgaacca caacttggac tcgacctatc     1440

atgcagcttg cagaagatgg tgcgtccgga tcagccacaa acagtaacaa ccatctaatc     1500

gagcctcaga tccgccggcc tcgtagcctc agctcgccaa cagtaacttt atctgccccg     1560

ctggagggtg ccaaggactc acccgtacgt cgggctgtga aagacaccct ttccaaccca     1620

cagtccccac agccatcacc ttacaactcc cccaaaccac aacacaaagt cacacagagc     1680

ttcttgccac ccggctggga aatgaggata gcgccaaacg gccggccctt cttcattgat     1740

cataacacaa agactacaac ctgggaagat ccacgtttga aatttccagt acatatgcgg     1800

tcaaagacat ctttaaaccc caatgacctt ggcccccttc ctcctggctg ggaagaaaga     1860

attcacttgg atggccgaac gttttatatt gatcataata gcaaaattac tcagtgggaa     1920

gacccaagac tgcagaaccc agctattact ggtccggctg tcccttactc cagagaattt     1980

aagcagaaat atgactactt caggaagaaa ttaaagaaac ctgctgatat ccccaatagg     2040

tttgaaatga aacttcacag aaataacata tttgaagagt cctatcggag aattatgtcc     2100

gtgaaaagac cagatgtcct aaaagctaga ctgtggattg agtttgaatc agagaaaggt     2160

cttgactatg ggggtgtggc cagagaatgg ttcttcttac tgtccaaaga gatgttcaac     2220

ccctactacg gcctctttga gtactctgcc acggacaact acacccttca gatcaaccct     2280

aattcaggcc tctgtaatga ggatcatttg tcctacttca cttttattgg aagagttgct     2340

ggtctggccg tatttcatgg gaagctctta gatggtttct tcattagacc attttacaag     2400

atgatgttgg gaaagcagat aaccctgaat gacatggaat ctgtggatag tgaatattac     2460

aactctttga aatggatcct ggagaatgac cctactgagc tggacctcat gttctgcata     2520

gacgaagaaa actttggaca gacatatcaa gtggatttga agcccaatgg gtcagaaata     2580

atggtcacaa atgaaaacaa aagggaatat atcgacttag tcatccagtg gagatttgtg     2640

aacagggtcc agaagcagat gaacgccttc ttggagggat tcacagaact acttcctatt     2700

gatttgatta aaatttttga tgaaaatgag ctggagttgc tcatgtgcgg cctcggtgat     2760

gtggatgtga atgactggag acagcattct atttacaaga acggctactg cccaaaccac     2820

cccgtcattc agtggttctg gaaggctgtg ctactcatgg acgccgaaaa gcgtatccgg     2880

ttactgcagt ttgtcacagg gacatcgcga gtacctatga atggatttgc cgaactttat     2940

ggttccaatg gtcctcagct gtttacaata gagcaatggg gcagtcctga gaaactgccc     3000

agagctcaca catgctttaa tcgccttgac ttacctccat atgaaacctt tgaagattta     3060

cgagagaaac ttctcatggc cgtggaaaat gctcaaggat ttgaaggggt ggattaagca     3120

ccctgtgcct cgggggtggt tgttcttcaa gcaagttctg cttgcacttt tgcatttgcc     3180

taacagactt ttgcagaggc gatggcagag agcagctgca ggcatggtcc ctggagccga     3240

gccttcacca cgcactcgtc caagttcgga tgcgggaacc tggtcccagc ttgagttcct     3300

gcctttccca ccacaaatta tcaactggtt gatgtgtaca ctaattacat ttcaggagga     3360

cttaatgcta tttatgttgt gcctctgcag gcaaagccct taataaatat tttacatcct     3420

ttctaatgac aatgaatgga attaatcact caacaggtat agtattacga ctcatgttta     3480

ctttttaaaa tgatttagac cgattttcag attttatttc gttatgatta aagatgtctc     3540

atgtacttgg aaaagtgagc attttttttt tttttgtatt tcactttcat accaggctta     3600

atgtcaatga catttttatt tttgaagtac tctgacacct ccaccctcta ctttattaga     3660

attggaaggc aaatttttgt ccaaaaacct acagacaagt actttgagag aatttccaat     3720

ataatattag acataatgat aattttttcc atactcagaa tgaaaaactg gatattacgt     3780

ttttgttttg gggttttttt gtacaaattt agctaatagc tacaggctga gagaattgta     3840

acatagcatg acaaattttg tgttgacttg aaaggaatca caccattatt ccttagaagt     3900

aattacatgt gttctaacac atttgagaca gggttggact cccatttctc atccgagaaa     3960

ttacttaacc cttcctggcg ctgtacagtc atcttttatt ctatttcctc tttgctgttt     4020

gtagtagaga cattttgaat gaaacttggc actgcttgat tcaaaactgt ggaaaccaga     4080

tctgtttagt ctcctgtttg tatgcgtttg ctaatggtag ctaaataacc agtttttgtt     4140

gtaaatgcac caattctgaa ggcactttat gtactacatg gaggtcatat ctggttttgt     4200

ttttattttt ttatcatgaa cattaaatgt gatgatgatt tcttttccct gcacacatct     4260

ttccggtgca atatctatca attgtgaatc tggctgctgg tgtataaaaa cctggatgta     4320

aagctgagcc tacagacctg tcctcaccaa ctgttttgtg atttctactc aactacaaag     4380

atttatttaa tgtactctta atctaactga gttttgttac caatgacctg ttgcatgctt     4440

caataccgtg tactgcctga gttgtgcctc ttgtgtgcta gattaaaagt gagacagaga     4500

cttgacttga tcctctgagc tcaagctatt gagctggtag tggcagagga ctgagggtac     4560

ctgcacagtt tgattctttt ccacgtgtaa gtctccattg cagaattgtc gtgctttgag     4620

aaaacacctg aggcagtgtg ggagttgaac gaccctgctg tcctttttaa cctgtgttgt     4680

cctagaccct gtcggggcag tcaggggaca ctagagattt gatctcatgc gagtcatcaa     4740

taggacaaaa aagttgtggt ttggggaggt ctgtttgtta cataaaaagg acctttcggt     4800

gtaagaaatt gccgttttta ccctgccctg gctggcatgt gagaagccat ggaaggttgt     4860

ggttgtaaat gagttgtcta aaggggtgca gaggcctgag gtttctaaaa gaaggtagat     4920

ttctacagag ctgagtgttg gttccttttt cttattggtt gaaaattacc tggtagtgat     4980

cagaaaactt agatgctatg taactaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     5040

aattcccgct catgagtttt gactattggt gagatgtttt ccgctacagt taacatgaca     5100

aatgtctcag tggcaaaaat cccctttttg taagccccca tagtctagag gcagttttct     5160

ttttaagaat catgccagag cctgagtcga gcagtatgct ttcttggttt ttgagagtaa     5220

ttgtgtaatt gtagagggag aaatccaatt ctaacctaag aactgggatt cttctgtcat     5280

cttgtaaacc gtatattgaa aaaaacagaa tgtcactaaa tgcatattaa gtcaagtatt     5340

ggaaagtata aaagaaaaat cattctgaca atttctaagc cagaagcaaa caagaattac     5400

tgaaatctac cccatgaata cttggaaggc agtaattgtg agtgacacct cagttcatca     5460

accccttaat aatatcagct taattttaat gacaactaaa tatgctgaag tgaggattta     5520

gtatttttta aaaaagcaaa acaaggttca gtagtcctca gcaattctcc aagtttctct     5580

ctttgcctaa aatggtcata gatcttgatt tctctgaatc gtgatgacca cacccagtca     5640

tcttcacagc ataattgcag gtggcagtaa agagagtgtg ctgggtaagg agcagttgct     5700

gggtcattcc ttgggccccg acctgcccgg ggagtagccc tgggggagag agggcagtgt     5760

tgcctatccc agaggtccca gcagtcacac tgctctgcag gccgggctct ctttatagcc     5820

agagaaatca ccttaatgca gtctctttag ttgtctgctg aagctgtagt tattatgggc     5880

cacttacatg aggctgagaa gtacgtgccg gagctcacac actgcctgtt gcggttctct     5940

taacatcagt tatcacagct gcctgtgggt cccgggtatt tccattcctg ccccttgttg     6000

gcccgaggaa ggatgtggaa agagcacctg gtgggatgaa ggtccaacag cctgtgcctc     6060

tccactgctg gccctggagc cggcagcagt gaggcattca ttgtctgtgt tgcggtgtat     6120

tcccagcttc agtgctcttt tcctttttgc ctgaaatgtt tatgcttctc tgcagccagt     6180

cctctaacaa atctcaagaa caaaggtaag acacttggtt tttgtttcca ggacccttca     6240

gaaggtgaca tcagatattc cctaaattca gacaatgagg gatacagagc gacttggcat     6300

gtattatttc tcccatgtaa ggacaaaggg acagattatt attgttattt ctgagacaga     6360

gtcttgctct gtagctcagg ctggagtgca gtggctcaat ctcagctcac cacaacctct     6420

gcctcctggc ttcaagcgat tcttctgcct cagcctcccc gaatagttgg gattacaggc     6480

acccaccacc acgcctggct aatttttgta tttttagtag agatggtttc accatgctgg     6540

ccaggctggt cttgaactcc tgacctcagg tgatcctccc gcctcagcct tccaaagtgc     6600

tgggattaca agcatgagcc accgcacccg gcctcacagt gacagattct gagaaacagc     6660

atgcaaaaca tttgaaccat tttctacatc tcccattgtt gcatagagag tgtgcaccgc     6720

tgctatcttg ccagatccac actggtcctc ccgaaagcca ggttcataca cagcaacttt     6780

ttaattattc taacagttac ccattaacag tcgactcctg tatttctgag agtcttgtac     6840

tcacctctga aatttaaaaa cgtataaaga gagcctgggt taatcagttc tgcagcccct     6900

acgtgacact gtgctagttc tccttcttct gtctcctcct taccctggcc ctgcacccct     6960

gtacttaaga gggagaggtg ggaggtgctg tctggtatca tttgctgcct cgccagtaga     7020

gggtgccgct gtgcagggta actgcccgcc tgctcccttc ctgacctccc ctgaccccga     7080

agatcactac ctctgtcatt caggcattgg ggtacatcct gataagtcgt gtcagaactg     7140

ccaatttcag gactgagatg tgtttttaaa aaacaaatcc ttataaactc cactttgtac     7200

tttagatttt aaaactgggg aaaaatgtga tattctttgg accacttttt taatttatat     7260

aagccttaat gaacagtgtc tatacatttg catacacaca cccccacccc agagtgttct     7320

cagtatgtca gagaaagtgc cacagcatta ggacgggagc ttggagaacg ttttctagaa     7380

aagggttagc ttcctgttgg catgaaattt tccaagcaaa cctcattaaa catctgttgt     7440

ttgttaaaga tgttccactg aaagcaacgc atgtttcaaa ggcacgtctt tccgttcgtt     7500

ggttttctgt gtgtaaggag tagcattgct gttggcgcct aacctcgcgt gcactgcatt     7560

ctcaaccccg taccagtgca tcatcagaag ccttcctcgt gaccataact ctgtgtctgc     7620

agatatgtgt tcccgtgtaa gccagttttc cccttttact cagactgatt tcacctagat     7680

tgtcacggtt tccttcatgt taactttgcg tgactttgtt cttcctttac tactctgtat     7740

gtaatatata tacatatata cgtacatatg ctgtccaaat atatttgtat atatttgtat     7800

agcattttta cacctttatt gagtaatctg gtttcgaaag gaggtgagag tttagtccct     7860

tctgcagttt tctccaagct gtgtcctgtg aatttcaacc cttggagcct aagaaaaccc     7920

taggaagatg atgttaattt gctgtcattt cctaattcag gatctatcat caaatgaaac     7980

atgaaaaaaa cagtgacttt taaggtgaaa agagtttcaa gcattccaaa taaattatca     8040

atgtttcata actttttatt ataaacccac ctcctaatag gaagccaagt actatttgat     8100

acagtggtaa aaaccaaact accttgaatt tttttaaggc aacttatgaa taatgctcat     8160

tttcacagtc agaatagctt taaaatatgg ttgaatttga tacacacagg aagttttctt     8220

gaagaacaat cctttcgctt ttcttttttc ttgagagatc taaagagaaa ctgtagattg     8280

ttttcctgac agcaaaagac taatgtgaca aaatgaagtc attgtaaaga agcgatgcaa     8340

cttgtcaaat atttaataaa gaattatgga agctggaaca ttttctac                  8388


<210>  1310
<211>  3148
<212>  DNA
<213>  homo sapiens

<400>  1310
ggagagcgcg ccacagaacg acttttacgc aggcgcagaa gcctgtttcc cctcacccgc       60

ggcttccacc ctgcgcaggc gcaaaaagcc gcgctggcaa cctccgcagc ggtcgcgcgc      120

acccttcacc cctcttgctg cttttgtctg gcacaacctt ctcaggccct ccgcgaggcc      180

ggcccttttt ttctttcact ttccccaccc ggagagccag gtgccgagaa ctaggacctc      240

gtccccttct ctatcccttc ccctgatcca tctcgtctct gttctccttc ccttttccgt      300

tcccgaagcc ggaaggagcc gaggtaccca cggaaaaagt cgaagctgtc cccggagagt      360

gaggccttca cgaagcggtg gcggaaggag ccgaagttct ctgatcggag gcgtgagcaa      420

gtggcatctc cggaaagagc cgaaacacgg actcgagctt aatcccagga ggggcccgag      480

ggcgagatcc ggaaatctcc ggaaagagcc gaaggccggg acggttagga ttgtcggaag      540

tggccgattg cttggacagg gccggcggag aagatcggag caagtccgtg gaagaagcca      600

aagactggga cggattgaat tgttggaaga acccgaactc gcagagggga ctgggcgcag      660

tggcacacga ggacacacgg aaacctccga acgttgagga gataatctcg gaaaagttac      720

ggaaacctgg gaagtcggcg aaaccctacg ttcgggtgtt ttcggaagca gccgaagcgg      780

ccgcctgctt cgccttcgtc cagtatccgg agatagccga ggcgcttcgg agccaggctc      840

ggggggaggg gcaagctcgc gggcgggcgg gcgggtgagg gggcggagcc cgggcggggc      900

ggggagggct gccggaggct tgattaggta ggaggtggcg aagcgccggc ggcggccgga      960

agtagccgaa gccagcggcg gaagtagccg aagcggctgg agcgggcggc aaggcgaggc     1020

gaaagctgca cagggcccta cgcggccgcc tcagcatgtc ggacttcgac gagttcgagc     1080

ggcagctcaa cgagaataaa caagagcggg acaaggagaa ccggcatcgg aagcgcagcc     1140

acagccgctc tcggagccgg gaccgcaaac gccggagccg gagccgcgac cggcgcaacc     1200

gggaccagcg gagcgcctcc cgggacaggc gacgacgcag caaacctttg accagaggcg     1260

ctaaagagga gcacggtgga ctgattcgtt ccccccgcca cgagaagaag aagaaggtcc     1320

gtaaatactg ggacgtgcca cccccaggct ttgagcacat caccccaatg cagtacaagg     1380

ccatgcaagc tgcgggtcag attccagcca ctgctcttct ccccaccatg acccctgacg     1440

gtctggctgt gaccccaacg ccggtgcccg tggtcgggag ccagatgacc agacaagccc     1500

ggcgcctcta cgtgggcaac atcccctttg gcatcactga ggaggccatg atggatttct     1560

tcaacgccca gatgcgcctg ggggggctga cccaggcccc tggcaaccca gtgttggctg     1620

tgcagattaa ccaggacaag aattttgcct ttttggagtt ccgctcagtg gacgagacta     1680

cccaggctat ggcctttgat ggcatcatct tccagggcca gtcactaaag atccgcaggc     1740

ctcacgacta ccagccgctt cctggcatgt cagagaaccc ctccgtctat gtgcctgggg     1800

ttgtgtccac tgtggtcccc gactctgccc acaagctgtt catcgggggc ttacccaact     1860

acctgaacga tgaccaggtc aaagagctgc tgacatcctt tgggcccctc aaggccttca     1920

acctggtcaa ggacagtgcc acggggctct ccaagggcta cgccttctgt gagtacgtgg     1980

acatcaacgt cacggatcag gccattgcgg ggctgaacgg catgcagctg ggggataaga     2040

agctgctggt ccagagggcg agtgtgggag ccaagaatgc cacgctggtg agccccccga     2100

gcaccatcaa tcagacgcct gtgaccctgc aagtgccggg cttgatgagc tcccaggtgc     2160

agatgggcgg ccacccgact gaggtcctgt gcctcatgaa catggtgctg cctgaggagc     2220

tgctggacga cgaggagtat gaggagatcg tggaggatgt gcgggacgag tgcagcaagt     2280

acgggcttgt caagtccatc gagatccccc ggcctgtgga cggcgtcgag gtgcccggct     2340

gcggaaagat ctttgtggag ttcacctctg tgtttgactg ccagaaagcc atgcagggcc     2400

tgacgggccg caagttcgcc aacagagtgg ttgtcacaaa atactgtgac cccgactctt     2460

atcaccgccg ggacttctgg tagaggcggc tgggggaggg tgggggcagg gctggctggg     2520

ggcttctccc cactcccgcc ccccccttat ccccctctga agacgatggg cagaggagtg     2580

acagccgcag acacacgaca gccggcagca actggaatgg cagcaattaa gggtgggggg     2640

cgggggttgg ggggttgggg ggttagggca gggaggggac tggggaagtg cgcacacagc     2700

ccacacagac aacacgcacc cacacagaca cagagggaag gggttgggat ggggacaggg     2760

tgcacagcag ggcggggtag gaccccagcc cctcccaaaa cagcctctcc ttctcccata     2820

gacccctttc ttctcccctt ccccacggta ggaacatagc gtgtttatat tttatggcca     2880

aactattttg aattttgttg tccggccctc agtgccctgc cctctccctt accaggacca     2940

cagctctgtt ccttcggcct ctggtcctct ctggtcccct cctgggtttc ttacgtagtt     3000

gatttttcct ctttagtctc ccccgacctg cgcccagccc cgtggcccct gcccctctcc     3060

tactctctgt ggcagtttca tatttgctaa gacgaatttg ctcattaaac attttgttgt     3120

attttacttt aaaaaaaaaa aaaaaaaa                                        3148


<210>  1311
<211>  3544
<212>  DNA
<213>  homo sapiens

<400>  1311
tcccagaccc ggggctctcc aaggccccgc gcttccgagc tccgcgcaaa ctctggcttc       60

tcttgtacga cagaggtggt ttgctcttcc gttgccccgt ggcttcagct catctttggc      120

aggaaggcga ggcttccgcc cggcacaggg gatgtccagc tcgccgctgt ccaagaaacg      180

tcgcgtgtcc gggcctgatc caaagccggg ttctaactgc tcccctgccc agtccgtgtt      240

gtccgaagtg ccctcggtgc caaccaacgg aatggccaag aacggcagtg aagcagacat      300

agacgagggc ctttactccc ggcagctgta tgtgttgggc catgaggcaa tgaagcggct      360

ccagacatcc agtgtcctgg tatcaggcct gcggggcctg ggcgtggaga tcgctaagaa      420

catcatcctt ggtggggtca aggctgttac cctacatgac cagggcactg cccagtgggc      480

tgatctttcc tcccagttct acctgcggga ggaggacatc ggtaaaaacc gggccgaggt      540

atcacagccc cgcctcgctg agctcaacag ctatgtgcct gtcactgcct acactggacc      600

cctcgttgag gacttcctta gtggtttcca ggtggtggtg ctcaccaaca cccccctgga      660

ggaccagctg cgagtgggtg agttctgtca caaccgtggc atcaagctgg tggtggcaga      720

cacgcggggc ctgtttgggc agctcttctg tgactttgga gaggaaatga tcctcacaga      780

ttccaatggg gagcagccac tcagtgctat ggtttctatg gttaccaagg acaaccccgg      840

tgtggttacc tgcctggatg aggcccgaca cgggtttgag agcggggact ttgtctcctt      900

ttcagaagta cagggcatgg ttgaactcaa cggaaatcag cccatggaga tcaaagtcct      960

gggtccttat acctttagca tctgtgacac ctccaacttc tccgactaca tccgtggagg     1020

catcgtcagt caggtcaaag tacctaagaa gattagcttt aaatccttgg tggcctcact     1080

ggcagaacct gactttgtgg tgacggactt cgccaagttt tctcgccctg cccagctgca     1140

cattggcttc caggccctgc accagttctg tgctcagcat ggccggccac ctcggccccg     1200

caatgaggag gatgcagcag aactggtagc cttagcacag gctgtgaatg ctcgagccct     1260

gccagcagtg cagcaaaata acctggacga ggacctcatc cggaagctgg catatgtggc     1320

tgctggggat ctggcaccca taaacgcctt cattgggggc ctggctgccc aggaagtcat     1380

gaaggcctgc tccgggaagt tcatgcccat catgcagtgg ctatactttg atgcccttga     1440

gtgtctccct gaggacaaag aggtcctcac agaggacaag tgcctccagc gccagaaccg     1500

ttatgacggg caagtggctg tgtttggctc agacctgcaa gagaagctgg gcaagcagaa     1560

gtatttcctg gtgggtgcgg gggccattgg ctgtgagctg ctcaagaact ttgccatgat     1620

tgggctgggc tgcggggagg gtggagaaat catcgttaca gacatggaca ccattgagaa     1680

gtcaaatctg aatcgacagt ttcttttccg gccctgggat gtcacgaagt taaagtctga     1740

cacggctgct gcagctgtgc gccaaatgaa tccacatatc cgggtgacaa gccaccagaa     1800

ccgtgtgggt cctgacacgg agcgcatcta tgatgacgat tttttccaaa acctagatgg     1860

cgtggccaat gccctggaca acgtggatgc ccgcatgtac atggaccgcc gctgtgtcta     1920

ctaccggaag ccactgctgg agtcaggcac actgggcacc aaaggcaatg tgcaggtggt     1980

gatccccttc ctgacagagt cgtacagttc cagccaggac ccacctgaga agtccatccc     2040

catctgtacc ctgaagaact tccctaatgc catcgagcac accctgcagt gggctcggga     2100

tgagtttgaa ggcctcttca agcagccagc agaaaatgtc aaccagtacc tcacagaccc     2160

caagtttgtg gagcgaacac tgcggctggc aggcactcag cccttggagg tgctggaggc     2220

tgtgcagcgc agcctggtgc tgcagcgacc acagacctgg gctgactgcg tgacctgggc     2280

ctgccaccac tggcacaccc agtactcgaa caacatccgg cagctgctgc acaacttccc     2340

tcctgaccag ctcacaagct caggagcgcc gttctggtct gggcccaaac gctgtccaca     2400

cccgctcacc tttgatgtca acaatcccct gcatctggac tatgtgatgg ctgctgccaa     2460

cctgtttgcc cagacctacg ggctgacagg ctctcaggac cgagctgctg tggccacatt     2520

cctgcagtct gtgcaggtcc ccgaattcac ccccaagtct ggcgtcaaga tccatgtttc     2580

tgaccaggag ctgcagagcg ccaatgcctc tgttgatgac agtcgtctag aggagctcaa     2640

agccactctg cccagcccag acaagctccc tggattcaag atgtacccca ttgactttga     2700

gaaggatgat gacagcaact ttcatatgga tttcatcgtg gctgcatcca acctccgggc     2760

agaaaactat gacattcctt ctgcagaccg gcacaagagc aagctgattg cagggaagat     2820

catcccagcc attgccacga ccacagcagc cgtggttggc cttgtgtgtc tggagctgta     2880

caaggttgtg caggggcacc gacagcttga ctcctacaag aatggtttcc tcaacttggc     2940

cctgcctttc tttggtttct ctgaacccct tgccgcacca cgtcaccagt actataacca     3000

agagtggaca ttgtgggatc gctttgaggt acaagggctg cagcctaatg gtgaggagat     3060

gaccctcaaa cagttcctcg actattttaa gacagagcac aaattagaga tcaccatgct     3120

gtcccagggc gtgtccatgc tctattcctt cttcatgcca gctgccaagc tcaaggaacg     3180

gttggatcag ccgatgacag agattgtgag ccgtgtgtcg aagcgaaagc tgggccgcca     3240

cgtgcgggcg ctggtgcttg agctgtgctg taacgacgag agcggcgagg atgtcgaggt     3300

tccctatgtc cgatacacca tccgctgacc ccgtctgctc ctctaggctg gccccttgtc     3360

cacccctctc cacacccctt ccagcccagg gttcccattt ggcttctggc agtggcccaa     3420

ctagccaagt ctggtgttcc ctcatcatcc ccctacctga acccctcttg ccactgcctt     3480

ctaccttgtt tgaaacctga atcctaataa agaattaata actcccaaaa aaaaaaaaaa     3540

aaaa                                                                  3544


<210>  1312
<211>  3616
<212>  DNA
<213>  homo sapiens

<400>  1312
gttccggccc caggctcagc gtccgccatc ttgtgtcggc ggctcggctg taaggaggtg       60

gcagggacaa ccacaaccac aacggccggg ggaggagaag gcggcagcgg cgattctagg      120

cggcccaggc ggcggggagg aggagaagga ggagggtggc ggccgggctt ggcttcggct      180

ccttgaggag ttggcggcgg cgcgacccgg ggaaccggca ttgatgtcca gctcgccgct      240

gtccaagaaa cgtcgcgtgt ccgggcctga tccaaagccg ggttctaact gctcccctgc      300

ccagtccgtg ttgtccgaag tgccctcggt gccaaccaac ggaatggcca agaacggcag      360

tgaagcagac atagacgagg gcctttactc ccggcagctg tatgtgttgg gccatgaggc      420

aatgaagcgg ctccagacat ccagtgtcct ggtatcaggc ctgcggggcc tgggcgtgga      480

gatcgctaag aacatcatcc ttggtggggt caaggctgtt accctacatg accagggcac      540

tgcccagtgg gctgatcttt cctcccagtt ctacctgcgg gaggaggaca tcggtaaaaa      600

ccgggccgag gtatcacagc cccgcctcgc tgagctcaac agctatgtgc ctgtcactgc      660

ctacactgga cccctcgttg aggacttcct tagtggtttc caggtggtgg tgctcaccaa      720

cacccccctg gaggaccagc tgcgagtggg tgagttctgt cacaaccgtg gcatcaagct      780

ggtggtggca gacacgcggg gcctgtttgg gcagctcttc tgtgactttg gagaggaaat      840

gatcctcaca gattccaatg gggagcagcc actcagtgct atggtttcta tggttaccaa      900

ggacaacccc ggtgtggtta cctgcctgga tgaggcccga cacgggtttg agagcgggga      960

ctttgtctcc ttttcagaag tacagggcat ggttgaactc aacggaaatc agcccatgga     1020

gatcaaagtc ctgggtcctt atacctttag catctgtgac acctccaact tctccgacta     1080

catccgtgga ggcatcgtca gtcaggtcaa agtacctaag aagattagct ttaaatcctt     1140

ggtggcctca ctggcagaac ctgactttgt ggtgacggac ttcgccaagt tttctcgccc     1200

tgcccagctg cacattggct tccaggccct gcaccagttc tgtgctcagc atggccggcc     1260

acctcggccc cgcaatgagg aggatgcagc agaactggta gccttagcac aggctgtgaa     1320

tgctcgagcc ctgccagcag tgcagcaaaa taacctggac gaggacctca tccggaagct     1380

ggcatatgtg gctgctgggg atctggcacc cataaacgcc ttcattgggg gcctggctgc     1440

ccaggaagtc atgaaggcct gctccgggaa gttcatgccc atcatgcagt ggctatactt     1500

tgatgccctt gagtgtctcc ctgaggacaa agaggtcctc acagaggaca agtgcctcca     1560

gcgccagaac cgttatgacg ggcaagtggc tgtgtttggc tcagacctgc aagagaagct     1620

gggcaagcag aagtatttcc tggtgggtgc gggggccatt ggctgtgagc tgctcaagaa     1680

ctttgccatg attgggctgg gctgcgggga gggtggagaa atcatcgtta cagacatgga     1740

caccattgag aagtcaaatc tgaatcgaca gtttcttttc cggccctggg atgtcacgaa     1800

gttaaagtct gacacggctg ctgcagctgt gcgccaaatg aatccacata tccgggtgac     1860

aagccaccag aaccgtgtgg gtcctgacac ggagcgcatc tatgatgacg attttttcca     1920

aaacctagat ggcgtggcca atgccctgga caacgtggat gcccgcatgt acatggaccg     1980

ccgctgtgtc tactaccgga agccactgct ggagtcaggc acactgggca ccaaaggcaa     2040

tgtgcaggtg gtgatcccct tcctgacaga gtcgtacagt tccagccagg acccacctga     2100

gaagtccatc cccatctgta ccctgaagaa cttccctaat gccatcgagc acaccctgca     2160

gtgggctcgg gatgagtttg aaggcctctt caagcagcca gcagaaaatg tcaaccagta     2220

cctcacagac cccaagtttg tggagcgaac actgcggctg gcaggcactc agcccttgga     2280

ggtgctggag gctgtgcagc gcagcctggt gctgcagcga ccacagacct gggctgactg     2340

cgtgacctgg gcctgccacc actggcacac ccagtactcg aacaacatcc ggcagctgct     2400

gcacaacttc cctcctgacc agctcacaag ctcaggagcg ccgttctggt ctgggcccaa     2460

acgctgtcca cacccgctca cctttgatgt caacaatccc ctgcatctgg actatgtgat     2520

ggctgctgcc aacctgtttg cccagaccta cgggctgaca ggctctcagg accgagctgc     2580

tgtggccaca ttcctgcagt ctgtgcaggt ccccgaattc acccccaagt ctggcgtcaa     2640

gatccatgtt tctgaccagg agctgcagag cgccaatgcc tctgttgatg acagtcgtct     2700

agaggagctc aaagccactc tgcccagccc agacaagctc cctggattca agatgtaccc     2760

cattgacttt gagaaggatg atgacagcaa ctttcatatg gatttcatcg tggctgcatc     2820

caacctccgg gcagaaaact atgacattcc ttctgcagac cggcacaaga gcaagctgat     2880

tgcagggaag atcatcccag ccattgccac gaccacagca gccgtggttg gccttgtgtg     2940

tctggagctg tacaaggttg tgcaggggca ccgacagctt gactcctaca agaatggttt     3000

cctcaacttg gccctgcctt tctttggttt ctctgaaccc cttgccgcac cacgtcacca     3060

gtactataac caagagtgga cattgtggga tcgctttgag gtacaagggc tgcagcctaa     3120

tggtgaggag atgaccctca aacagttcct cgactatttt aagacagagc acaaattaga     3180

gatcaccatg ctgtcccagg gcgtgtccat gctctattcc ttcttcatgc cagctgccaa     3240

gctcaaggaa cggttggatc agccgatgac agagattgtg agccgtgtgt cgaagcgaaa     3300

gctgggccgc cacgtgcggg cgctggtgct tgagctgtgc tgtaacgacg agagcggcga     3360

ggatgtcgag gttccctatg tccgatacac catccgctga ccccgtctgc tcctctaggc     3420

tggccccttg tccacccctc tccacacccc ttccagccca gggttcccat ttggcttctg     3480

gcagtggccc aactagccaa gtctggtgtt ccctcatcat ccccctacct gaacccctct     3540

tgccactgcc ttctaccttg tttgaaacct gaatcctaat aaagaattaa taactcccaa     3600

aaaaaaaaaa aaaaaa                                                     3616


<210>  1313
<211>  3544
<212>  DNA
<213>  homo sapiens

<400>  1313
tcccagaccc ggggctctcc aaggccccgc gcttccgagc tccgcgcaaa ctctggcttc       60

tcttgtacga cagaggtggt ttgctcttcc gttgccccgt ggcttcagct catctttggc      120

aggaaggcga ggcttccgcc cggcacaggg gatgtccagc tcgccgctgt ccaagaaacg      180

tcgcgtgtcc gggcctgatc caaagccggg ttctaactgc tcccctgccc agtccgtgtt      240

gtccgaagtg ccctcggtgc caaccaacgg aatggccaag aacggcagtg aagcagacat      300

agacgagggc ctttactccc ggcagctgta tgtgttgggc catgaggcaa tgaagcggct      360

ccagacatcc agtgtcctgg tatcaggcct gcggggcctg ggcgtggaga tcgctaagaa      420

catcatcctt ggtggggtca aggctgttac cctacatgac cagggcactg cccagtgggc      480

tgatctttcc tcccagttct acctgcggga ggaggacatc ggtaaaaacc gggccgaggt      540

atcacagccc cgcctcgctg agctcaacag ctatgtgcct gtcactgcct acactggacc      600

cctcgttgag gacttcctta gtggtttcca ggtggtggtg ctcaccaaca cccccctgga      660

ggaccagctg cgagtgggtg agttctgtca caaccgtggc atcaagctgg tggtggcaga      720

cacgcggggc ctgtttgggc agctcttctg tgactttgga gaggaaatga tcctcacaga      780

ttccaatggg gagcagccac tcagtgctat ggtttctatg gttaccaagg acaaccccgg      840

tgtggttacc tgcctggatg aggcccgaca cgggtttgag agcggggact ttgtctcctt      900

ttcagaagta cagggcatgg ttgaactcaa cggaaatcag cccatggaga tcaaagtcct      960

gggtccttat acctttagca tctgtgacac ctccaacttc tccgactaca tccgtggagg     1020

catcgtcagt caggtcaaag tacctaagaa gattagcttt aaatccttgg tggcctcact     1080

ggcagaacct gactttgtgg tgacggactt cgccaagttt tctcgccctg cccagctgca     1140

cattggcttc caggccctgc accagttctg tgctcagcat ggccggccac ctcggccccg     1200

caatgaggag gatgcagcag aactggtagc cttagcacag gctgtgaatg ctcgagccct     1260

gccagcagtg cagcaaaata acctggacga ggacctcatc cggaagctgg catatgtggc     1320

tgctggggat ctggcaccca taaacgcctt cattgggggc ctggctgccc aggaagtcat     1380

gaaggcctgc tccgggaagt tcatgcccat catgcagtgg ctatactttg atgcccttga     1440

gtgtctccct gaggacaaag aggtcctcac agaggacaag tgcctccagc gccagaaccg     1500

ttatgacggg caagtggctg tgtttggctc agacctgcaa gagaagctgg gcaagcagaa     1560

gtatttcctg gtgggtgcgg gggccattgg ctgtgagctg ctcaagaact ttgccatgat     1620

tgggctgggc tgcggggagg gtggagaaat catcgttaca gacatggaca ccattgagaa     1680

gtcaaatctg aatcgacagt ttcttttccg gccctgggat gtcacgaagt taaagtctga     1740

cacggctgct gcagctgtgc gccaaatgaa tccacatatc cgggtgacaa gccaccagaa     1800

ccgtgtgggt cctgacacgg agcgcatcta tgatgacgat tttttccaaa acctagatgg     1860

cgtggccaat gccctggaca acgtggatgc ccgcatgtac atggaccgcc gctgtgtcta     1920

ctaccggaag ccactgctgg agtcaggcac actgggcacc aaaggcaatg tgcaggtggt     1980

gatccccttc ctgacagagt cgtacagttc cagccaggac ccacctgaga agtccatccc     2040

catctgtacc ctgaagaact tccctaatgc catcgagcac accctgcagt gggctcggga     2100

tgagtttgaa ggcctcttca agcagccagc agaaaatgtc aaccagtacc tcacagaccc     2160

caagtttgtg gagcgaacac tgcggctggc aggcactcag cccttggagg tgctggaggc     2220

tgtgcagcgc agcctggtgc tgcagcgacc acagacctgg gctgactgcg tgacctgggc     2280

ctgccaccac tggcacaccc agtactcgaa caacatccgg cagctgctgc acaacttccc     2340

tcctgaccag ctcacaagct caggagcgcc gttctggtct gggcccaaac gctgtccaca     2400

cccgctcacc tttgatgtca acaatcccct gcatctggac tatgtgatgg ctgctgccaa     2460

cctgtttgcc cagacctacg ggctgacagg ctctcaggac cgagctgctg tggccacatt     2520

cctgcagtct gtgcaggtcc ccgaattcac ccccaagtct ggcgtcaaga tccatgtttc     2580

tgaccaggag ctgcagagcg ccaatgcctc tgttgatgac agtcgtctag aggagctcaa     2640

agccactctg cccagcccag acaagctccc tggattcaag atgtacccca ttgactttga     2700

gaaggatgat gacagcaact ttcatatgga tttcatcgtg gctgcatcca acctccgggc     2760

agaaaactat gacattcctt ctgcagaccg gcacaagagc aagctgattg cagggaagat     2820

catcccagcc attgccacga ccacagcagc cgtggttggc cttgtgtgtc tggagctgta     2880

caaggttgtg caggggcacc gacagcttga ctcctacaag aatggtttcc tcaacttggc     2940

cctgcctttc tttggtttct ctgaacccct tgccgcacca cgtcaccagt actataacca     3000

agagtggaca ttgtgggatc gctttgaggt acaagggctg cagcctaatg gtgaggagat     3060

gaccctcaaa cagttcctcg actattttaa gacagagcac aaattagaga tcaccatgct     3120

gtcccagggc gtgtccatgc tctattcctt cttcatgcca gctgccaagc tcaaggaacg     3180

gttggatcag ccgatgacag agattgtgag ccgtgtgtcg aagcgaaagc tgggccgcca     3240

cgtgcgggcg ctggtgcttg agctgtgctg taacgacgag agcggcgagg atgtcgaggt     3300

tccctatgtc cgatacacca tccgctgacc ccgtctgctc ctctaggctg gccccttgtc     3360

cacccctctc cacacccctt ccagcccagg gttcccattt ggcttctggc agtggcccaa     3420

ctagccaagt ctggtgttcc ctcatcatcc ccctacctga acccctcttg ccactgcctt     3480

ctaccttgtt tgaaacctga atcctaataa agaattaata actcccaaaa aaaaaaaaaa     3540

aaaa                                                                  3544


<210>  1314
<211>  3312
<212>  DNA
<213>  homo sapiens

<400>  1314
tttggcatcc aggagaccgt gcgggagacc gacgctgagc gccggcctcg ccctcggcgg       60

cccctccctc ctccttaccc cgcctccccc ggcccgcccc tccctccccg gaggagcagt      120

ctctccgcgc gtctcccgga gctttctcca ttgtctctgc ctttacaaca gagggagacg      180

atggactgag ctgatccgca ccatggagtc tcgggtctta ctgagaacat tctgtttgat      240

cttcggtctc ggagcagttt gggggcttgg tgtggaccct tccctacaga ttgacgtctt      300

aacagagtta gaacttgggg agtccacgac cggagtgcgt caggtcccgg ggctgcataa      360

tgggacgaaa gcctttctct ttcaagatac tcccagaagc ataaaagcat ccactgctac      420

agctgaacag ttttttcaga agctgagaaa taaacatgaa tttactattt tggtgaccct      480

aaaacagacc cacttaaatt caggagttat tctctcaatt caccacttgg atcacaggta      540

cctggaactg gaaagtagtg gccatcggaa tgaagtcaga ctgcattacc gctcaggcag      600

tcaccgccct cacacagaag tgtttcctta cattttggct gatgacaagt ggcacaagct      660

ctccttagcc atcagtgctt cccatttgat tttacacatt gactgcaata aaatttatga      720

aagggtagta gaaaagccct ccacagactt gcctctaggc acaacatttt ggctaggaca      780

gagaaataat gcgcatggat attttaaggg tataatgcaa gatgtccaat tacttgtcat      840

gccccaggga tttattgctc agtgcccaga tcttaatcgc acctgtccaa cttgcaatga      900

cttccatgga cttgtgcaga aaatcatgga gctacaggat attttagcca aaacatcagc      960

caagctgtct cgagctgaac agcgaatgaa tagattggat cagtgctatt gtgaaaggac     1020

ttgcaccatg aagggaacca cctaccgaga atttgagtcc tggatagacg gctgtaagaa     1080

ctgcacatgc ctgaatggaa ccatccagtg tgaaactcta atctgcccaa atcctgactg     1140

cccacttaag tcggctcttg cgtatgtgga tggcaaatgc tgtaaggaat gcaaatcgat     1200

atgccaattt caaggacgaa cctactttga aggagaaaga aatacagtct attcctcttc     1260

tggagtatgt gttctctatg agtgcaagga ccagaccatg aaacttgttg agagttcagg     1320

ctgtccagct ttggattgtc cagagtctca tcagataacc ttgtctcaca gctgttgcaa     1380

agtttgtaaa ggttatgact tttgttctga aaggcataac tgcatggaga attccatctg     1440

cagaaatctg aatgacaggg ctgtttgtag ctgtcgagat ggttttaggg ctcttcgaga     1500

ggataatgcc tactgtgaag acatcgatga gtgtgctgaa gggcgccatt actgtcgtga     1560

aaatacaatg tgtgtcaaca ccccgggttc ttttatgtgc atctgcaaaa ctggatacat     1620

cagaattgat gattattcat gtacagaaca tgatgagtgt atcacaaatc agcacaactg     1680

tgatgaaaat gctttatgct tcaacactgt tggaggacac aactgtgttt gcaagccggg     1740

ctatacaggg aatggaacga catgcaaagc attttgcaaa gatggctgta ggaatggagg     1800

agcctgtatt gccgctaatg tgtgtgcctg cccacaaggc ttcactggac ccagctgtga     1860

aacggacatt gatgaatgct ctgatggttt tgttcaatgt gacagtcgtg ctaattgcat     1920

taacctgcct ggatggtacc actgtgagtg cagagatggc taccatgaca atgggatgtt     1980

ttcaccaagt ggagaatcgt gtgaagatat tgatgagtgt gggaccggga ggcacagctg     2040

tgccaatgat accatttgct tcaatttgga tggcggatat gattgtcgat gtcctcatgg     2100

aaagaattgc acaggggact gcatccatga tggaaaagtt aagcacaatg gtcagatttg     2160

ggtgttggaa aatgacaggt gctctgtgtg ctcatgtcag aatggattcg ttatgtgtcg     2220

acggatggtc tgtgactgtg agaatcccac agttgatctt ttttgctgcc ctgaatgtga     2280

cccaaggctt agtagtcagt gcctccatca aaatggggaa actttgtata acagtggtga     2340

cacctgggtc cagaattgtc aacagtgccg ctgcttgcaa ggggaagttg attgttggcc     2400

cctgccttgc ccagatgtgg agtgtgaatt cagcattctc ccagagaatg agtgctgccc     2460

gcgctgtgtc acagaccctt gccaggctga caccatccgc aatgacatca ccaagacttg     2520

cctggacgaa atgaatgtgg ttcgcttcac cgggtcctct tggatcaaac atggcactga     2580

gtgtactctc tgccagtgca agaatggcca catctgttgc tcagtggatc cacagtgcct     2640

tcaggaactg tgaagttaac tgtctcatgg gagatttctg ttaaaagaat gttctttcat     2700

taaaagacca aaaagaagtt aaaacttaaa ttgggtgatt tgtgggcagc taaatgcagc     2760

tttgttaata gctgagtgaa ctttcaatta tgaaatttgt ggagcttgac aaaatcacaa     2820

aaggaaaatt actggggcaa aattagacct caagtctgcc tctactgtgt ctcacatcac     2880

catgtagaag aatgggcgta cagtatatac cgtgacatcc tgaaccctgg atagaaagcc     2940

tgagcccatt ggatctgtga aagcctctag cttcactggt gcagaaaatt ttcctctaga     3000

tcagaatctt caagaatcag ttaggttcct cactgcaaga aataaaatgt caggcagtga     3060

atgaattata ttttcagaag taaagcaaag aagctataac atgttatgta cagtacactc     3120

tgaaaagaaa tctgaaacaa gttattgtaa tgataaaaat aatgcacagg catggttact     3180

taatattttc taacaggaaa agtcatccct atttccttgt tttactgcac ttaatattat     3240

ttggttgaat ttgttcagta taagctcgtt cttgtgcaaa attaaataaa tatttctctt     3300

accttataac ac                                                         3312


<210>  1315
<211>  3385
<212>  DNA
<213>  homo sapiens

<400>  1315
ctctacctac tttgcccagc tccacctcgg cagtgcagcg tgttttggtg gccttcctcc       60

gcacgccctg gagggggagt gccctgcacc ccggggctgc tccggagccc agtgcacgag      120

tgcacatggg cttccctcct ttgcttaaag ggcaggcgag cgctactcgc tccagccttg      180

cctcctgcag ctgggtggtc ttttttctct cctgtctttc aagacacgcg cccgaaatcg      240

agggagggag acgatggact gagctgatcc gcaccatgga gtctcgggtc ttactgagaa      300

cattctgttt gatcttcggt ctcggagcag tttgggggct tggtgtggac ccttccctac      360

agattgacgt cttaacagag ttagaacttg gggagtccac gaccggagtg cgtcaggtcc      420

cggggctgca taatgggacg aaagcctttc tctttcaaga tactcccaga agcataaaag      480

catccactgc tacagctgaa cagttttttc agaagctgag aaataaacat gaatttacta      540

ttttggtgac cctaaaacag acccacttaa attcaggagt tattctctca attcaccact      600

tggatcacag gtacctggaa ctggaaagta gtggccatcg gaatgaagtc agactgcatt      660

accgctcagg cagtcaccgc cctcacacag aagtgtttcc ttacattttg gctgatgaca      720

agtggcacaa gctctcctta gccatcagtg cttcccattt gattttacac attgactgca      780

ataaaattta tgaaagggta gtagaaaagc cctccacaga cttgcctcta ggcacaacat      840

tttggctagg acagagaaat aatgcgcatg gatattttaa gggtataatg caagatgtcc      900

aattacttgt catgccccag ggatttattg ctcagtgccc agatcttaat cgcacctgtc      960

caacttgcaa tgacttccat ggacttgtgc agaaaatcat ggagctacag gatattttag     1020

ccaaaacatc agccaagctg tctcgagctg aacagcgaat gaatagattg gatcagtgct     1080

attgtgaaag gacttgcacc atgaagggaa ccacctaccg agaatttgag tcctggatag     1140

acggctgtaa gaactgcaca tgcctgaatg gaaccatcca gtgtgaaact ctaatctgcc     1200

caaatcctga ctgcccactt aagtcggctc ttgcgtatgt ggatggcaaa tgctgtaagg     1260

aatgcaaatc gatatgccaa tttcaaggac gaacctactt tgaaggagaa agaaatacag     1320

tctattcctc ttctggagta tgtgttctct atgagtgcaa ggaccagacc atgaaacttg     1380

ttgagagttc aggctgtcca gctttggatt gtccagagtc tcatcagata accttgtctc     1440

acagctgttg caaagtttgt aaaggttatg acttttgttc tgaaaggcat aactgcatgg     1500

agaattccat ctgcagaaat ctgaatgaca gggctgtttg tagctgtcga gatggtttta     1560

gggctcttcg agaggataat gcctactgtg aagacatcga tgagtgtgct gaagggcgcc     1620

attactgtcg tgaaaataca atgtgtgtca acaccccggg ttcttttatg tgcatctgca     1680

aaactggata catcagaatt gatgattatt catgtacaga acatgatgag tgtatcacaa     1740

atcagcacaa ctgtgatgaa aatgctttat gcttcaacac tgttggagga cacaactgtg     1800

tttgcaagcc gggctataca gggaatggaa cgacatgcaa agcattttgc aaagatggct     1860

gtaggaatgg aggagcctgt attgccgcta atgtgtgtgc ctgcccacaa ggcttcactg     1920

gacccagctg tgaaacggac attgatgaat gctctgatgg ttttgttcaa tgtgacagtc     1980

gtgctaattg cattaacctg cctggatggt accactgtga gtgcagagat ggctaccatg     2040

acaatgggat gttttcacca agtggagaat cgtgtgaaga tattgatgag tgtgggaccg     2100

ggaggcacag ctgtgccaat gataccattt gcttcaattt ggatggcgga tatgattgtc     2160

gatgtcctca tggaaagaat tgcacagggg actgcatcca tgatggaaaa gttaagcaca     2220

atggtcagat ttgggtgttg gaaaatgaca ggtgctctgt gtgctcatgt cagaatggat     2280

tcgttatgtg tcgacggatg gtctgtgact gtgagaatcc cacagttgat cttttttgct     2340

gccctgaatg tgacccaagg cttagtagtc agtgcctcca tcaaaatggg gaaactttgt     2400

ataacagtgg tgacacctgg gtccagaatt gtcaacagtg ccgctgcttg caaggggaag     2460

ttgattgttg gcccctgcct tgcccagatg tggagtgtga attcagcatt ctcccagaga     2520

atgagtgctg cccgcgctgt gtcacagacc cttgccaggc tgacaccatc cgcaatgaca     2580

tcaccaagac ttgcctggac gaaatgaatg tggttcgctt caccgggtcc tcttggatca     2640

aacatggcac tgagtgtact ctctgccagt gcaagaatgg ccacatctgt tgctcagtgg     2700

atccacagtg ccttcaggaa ctgtgaagtt aactgtctca tgggagattt ctgttaaaag     2760

aatgttcttt cattaaaaga ccaaaaagaa gttaaaactt aaattgggtg atttgtgggc     2820

agctaaatgc agctttgtta atagctgagt gaactttcaa ttatgaaatt tgtggagctt     2880

gacaaaatca caaaaggaaa attactgggg caaaattaga cctcaagtct gcctctactg     2940

tgtctcacat caccatgtag aagaatgggc gtacagtata taccgtgaca tcctgaaccc     3000

tggatagaaa gcctgagccc attggatctg tgaaagcctc tagcttcact ggtgcagaaa     3060

attttcctct agatcagaat cttcaagaat cagttaggtt cctcactgca agaaataaaa     3120

tgtcaggcag tgaatgaatt atattttcag aagtaaagca aagaagctat aacatgttat     3180

gtacagtaca ctctgaaaag aaatctgaaa caagttattg taatgataaa aataatgcac     3240

aggcatggtt acttaatatt ttctaacagg aaaagtcatc cctatttcct tgttttactg     3300

cacttaatat tatttggttg aatttgttca gtataagctc gttcttgtgc aaaattaaat     3360

aaatatttct cttaccttat aacac                                           3385


<210>  1316
<211>  1196
<212>  DNA
<213>  homo sapiens

<400>  1316
ggaaaacggc ggccgcggcg tctcctccgg gacgctgagg ggcccgagga gaccgtgagg       60

ctctggcctg cagctcgcgc cgccatggac gctgccgagg tcgaattcct cgccgagaag      120

gagctggtta ccattatccc caacttcagt ctggacaaga tctacctcat cgggggggac      180

ctggggcctt ttaaccctgg tttacccgtg gaagtgcccc tgtggctggc gattaacctg      240

aaacaaagac agaaatgtcg cctgctccct ccagagtgga tggatgtaga aaagttggag      300

aagatgaggg atcatgaacg aaaggaagaa acttttaccc caatgcccag cccttactac      360

atggaactta cgaagctcct gttaaatcat gcttcagaca acatcccgaa ggcagacgaa      420

atccggaccc tggtcaagga tatgtgggac actcgtatag ccaaactccg agtgtctgct      480

gacagctttg tgagacagca ggaggcacat gccaagctgg ataacttgac cttgatggag      540

atcaacacca gcgggacttt cctcacacaa gcgctcaacc acatgtacaa actccgcacg      600

aacctccagc ctctggagag tactcagtct caggacttct agagaaaggc ctggtgcagg      660

cggcttgctg ggggatgtga gcgctcagga cgtgatgagg tactcgtggt tctggagctc      720

tagaaacact tctgatgcat gaaaaatgtg tgatggtgca aggaatggat tcaggatgtt      780

gttggagaaa caagtttgtg attagtcctt aaaacttagc tccctgggac attcttcaat      840

tccacatctg tttctagaaa ccagcccttt ttccccccac ttttgagaaa taaaaaagcc      900

ttaggtaaat aagtcattct ccctagcaga gccacttggg tctcctgcat ggaagccatc      960

acacttgggc aggtgttcag tgactggtag gtgtagatac agcaggagtg gccatgtggt     1020

ccacggcttt ttaccccttc ttgatcctga tttcttgggc tgaatttaga ctctctcaca     1080

gaggtggctc acagagaagg atggcagatg gtgcagccaa caatgctgac cggtgcttat     1140

cctctaagcc ctgatccaca ataaaaatgg acccaactca aaaaaaaaaa aaaaaa         1196


<210>  1317
<211>  1964
<212>  DNA
<213>  homo sapiens

<400>  1317
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag cagatgaaga      120

aactgaggcc ctgtgatgtg aagtgacttg ccccccagcc acacagctgg accattctgg      180

ctgctgtctg gacaagaagt cgtagggggt gagggtggaa gctgggaaac ccacaggagg      240

caaccacact agtttagatc ttctggtgac cccacttctc gctgctcatg ccgctgggac      300

tggggcggcg gaaaaaggcg ccccctctag tggaaaatga ggaggctgag ccaggccgtg      360

gagggctggg cgtgggggag ccagggcctc tgggcggagg tgggtcgggg ggcccccaaa      420

tgggcttgcc cccccctccc ccagccctgc ggccccgcct cgtgttccac acccagctgg      480

cccatggcag tcccactggc cgcatcgagg gcttcaccaa cgtcaaggag ctgtatggca      540

agatcgccga ggccttccgc ctgccaactg ccgaggtgat gttctgcacc ctgaacaccc      600

acaaagtgga catggacaag ctcctggggg gccagatcgg gctggaggac ttcatcttcg      660

cccacgtgaa ggggcagcgc aaggaggtgg aggtgttcaa gtcggaggat gcactcgggc      720

tcaccatcac ggacaacggg gctggctacg ccttcatcaa gcgcatcaag gagggcagcg      780

tgatcgacca catccacctc atcagcgtgg gcgacatgat cgaggccatt aacgggcaga      840

gcctgctggg ctgccggcac tacgaggtgg cccggctgct caaggagctg ccccgaggcc      900

gtaccttcac gctgaagctc acggagcctc gcaaggcctt cgacatgatc agccagcgtt      960

cagcgggtgg ccgccctggc tctggcccac aactgggcac tggccgaggg accctgcggc     1020

tccgatcccg gggccccgcc acggtggagg atctgccctc tgcctttgaa gagaaggcca     1080

ttgagaaggt ggatgacctg ctggagagtt acatgggtat cagggacacg gagctggcgg     1140

ccaccatggt ggagctggga aaggacaaaa ggaacccgga tgagctggcc gaggccctgg     1200

acgaacggct gggtgacttt gccttccctg acgagttcgt ctttgacgtc tggggcgcca     1260

ttggggacgc caaggtcggc cgctactagg actgcccccg gaccctgcga tgatgacccg     1320

ggcgcaacct ggtgggggcc cccagcaggg acactgacgt caggacccga gcctccagcc     1380

tgagcctagc tcagcagccc aaggacgatg gtgaggggag gtggggccag gccccctgcc     1440

ccgctccaat cggtaccatc ccctccctgg ttcccagtct ggccggggtc cccggccccc     1500

ctgtgccctg ttccccacct acctcagctg ggtcaggcac agggagggga gggatcagcc     1560

aaattgggcg gccacccccg cctccaccac tttccaccat cagctgccaa actggtccct     1620

ctgtctccct ggggccttgg gttctgtttg ggggtcatga ccttcctagt ttcctgacgc     1680

agggaataca ggggagaggg ttgtccttcc ccccagcaaa tgcaataatg ccctcacccc     1740

tcctgagagg agccccctcc ctgtggagcc tgttacctcc gcatttgaca cgagtctgct     1800

gtgaaccccg caacctcctc cccacctccc atctctcctt ccaggcccat ccctggccca     1860

gagcaggagg gagggaggga cgatggcggt gggtttttgt atctgaattt gctgtcttga     1920

acataaagaa tctatctgct gttggaaaaa aaaaaaaaaa aaaa                      1964


<210>  1318
<211>  7667
<212>  DNA
<213>  homo sapiens

<400>  1318
gtccgggttc gcttgcctcg tcagcgtccg cgtttttccc ggcccccccc aacccccccg       60

gacaggaccc ccttgagctt gtccctcagc tgccaccatg agcgaccaag atcactccat      120

ggatgaaatg acagctgtgg tgaaaattga aaaaggagtt ggtggcaata atgggggcaa      180

tggtaatggt ggtggtgcct tttcacaggc tcgaagtagc agcacaggca gtagcagcag      240

cactggagga ggagggcagg agtcccagcc atcccctttg gctctgctgg cagcaacttg      300

cagcagaatt gagtcaccca atgagaacag caacaactcc cagggcccga gtcagtcagg      360

gggaacaggt gagcttgacc tcacagccac acaactttca cagggtgcca atggctggca      420

gatcatctct tcctcctctg gggctacccc tacctcaaag gaacagagtg gcagcagtac      480

caatggcagc aatggcagtg agtcttccaa gaatcgcaca gtctctggtg ggcagtatgt      540

tgtggctgcc gctcccaact tacagaacca gcaagttctg acaggactac ctggagtgat      600

gcctaatatt cagtatcaag taatcccaca gttccagacc gttgatgggc aacagctgca      660

gtttgctgcc actggggccc aagtgcagca ggatggttct ggtcaaatac agatcatacc      720

aggtgcaaac caacagatta tcacaaatcg aggaagtgga ggcaacatca ttgctgctat      780

gccaaaccta ctccagcagg ctgtccccct ccaaggcctg gctaataatg tactctcagg      840

acagactcag tatgtgacca atgtaccagt ggccctgaat gggaacatca ccttgctacc      900

tgtcaacagc gtttctgcag ctaccttgac tcccagctct caggcagtca cgatcagcag      960

ctctgggtcc caggagagtg gctcacagcc tgtcacctca gggactacca tcagttctgc     1020

cagcttggta tcatcacaag ccagttccag ctcctttttc accaatgcca atagctactc     1080

aactactact accaccagca acatgggaat tatgaacttt actaccagtg gatcatcagg     1140

gaccaactct caaggccaga caccccagag ggtcagtggg ctacaggggt ctgatgctct     1200

gaacatccag caaaaccaga catctggagg ctcattgcaa gcaggccagc aaaaagaagg     1260

agagcaaaac cagcagacac agcagcaaca aattcttatc cagcctcagc tagttcaagg     1320

gggacaggcc ctccaggccc tccaagcagc accattgtca gggcagacct ttacaactca     1380

agccatctcc caggaaaccc tccagaacct ccagcttcag gctgttccaa actctggtcc     1440

catcatcatc cggacaccaa cagtggggcc caatggacag gtcagttggc agactctaca     1500

gctgcagaac ctccaagttc agaacccaca agcccaaaca atcaccttag ccccaatgca     1560

gggtgtttcc ttggggcaga ccagcagcag caacaccact ctcacaccca ttgcctcagc     1620

tgcttccatt cctgctggca cagtcactgt gaatgctgct caactctcct ccatgccagg     1680

cctccagacc attaacctca gtgcattggg tacttcagga atccaggtgc acccaattca     1740

aggcctgccg ttggctatag caaatgcccc aggtgatcat ggagctcagc ttggtctcca     1800

tggggctggt ggtgatggaa tacatgatga cacagcaggt ggagaggaag gagaaaacag     1860

cccagatgcc caaccccaag ccggtcggag gacccggcgg gaagcatgca cctgccccta     1920

ctgtaaagac agtgaaggaa ggggctcggg ggatcctggc aaaaagaaac agcatatttg     1980

ccacatccaa ggctgtggga aagtgtatgg caagacctct cacctgcggg cacacttgcg     2040

ctggcataca ggcgagaggc catttatgtg tacctggtca tactgtggga aacgcttcac     2100

acgttcggat gagctacaga ggcacaaacg tacacacaca ggtgagaaga aatttgcctg     2160

ccctgagtgt cctaagcgct tcatgaggag tgaccacctg tcaaaacata tcaagaccca     2220

ccagaataag aagggaggcc caggtgtagc tctgagtgtg ggcactttgc ccctggacag     2280

tggggcaggt tcagaaggca gtggcactgc cactccttca gcccttatta ccaccaatat     2340

ggtagccatg gaggccatct gtccagaggg cattgcccgt cttgccaaca gtggcatcaa     2400

cgtcatgcag gtggcagatc tgcagtccat taatatcagt ggcaatggct tctgagatca     2460

ggcacccggg gccagagaca tatgggccat accccttaac cccgggatgc aaggtagcat     2520

gggtccaaga gacatggaag agagagccat gaagcattaa aatgcatggt gttgagaaga     2580

atcaggagag ggatacaaga gaggagatgg ggtcccggca cccatctgta tcatcagtgc     2640

ctctttgaag gtgggaaaca ttagtgaaaa ttctgttggt gccacgcttt gatgagcatt     2700

tgtttgaccc cagtttcttc ttacacttct taccccagcc tacccttcct gcatttctct     2760

tctcagctct tccatgatgg attccccccc ctttcctaaa gccatcatgc cttgataaat     2820

atatatgatc attgaaatac tttttaacaa aaaacagatt ctatattatt atatatatat     2880

atatatatat aaagatatat agagatgcat tcacaggggt tggctgggag gaggaagacc     2940

attctgtgac caaaatacct tggtcatttt ttttatattg ccttatttcc ctatggctga     3000

gccttgttgt gacacatcaa gcttttctgt agatgttgtc ttggcttccc accagcttaa     3060

gcgttcatat gctctgcttt tagttcatat atacatacat aatgtttttc ctttcttaat     3120

tttgtctttt tgtttgggat cagcttcttg cactccttcc ctaactcaac tgttgccgtc     3180

tcatcttctc tcatctgatc acttcatgtt ttgtttttgt tactgcctgg atgaggcact     3240

tctgtcaatt ttttcaggac cttagttcca gcagcagaat ggaaaaatcc ttgaagccca     3300

ggctgatgct tgaagtaact gtggagggag tgttcaaaat actactgacg caggcacctt     3360

cttggcgctg gagagtcaaa ggcatctccc ttcattagct gctctgagca tcaagaatta     3420

gaagtctttc agtggaattg tacaagagtc cctttgaaga taataatctt ggctcagttt     3480

gtataaactg tcaaattttc aaataatagg tagggggctt tcactaggaa aatcatgtgc     3540

tcagaagagg aaatgactcg tagtcaggtt caggagttag tggagtattt ggactttggt     3600

actgctgtct tccaaggtag ctctaagttt tgatgtgtgg gcttctgagt ttatattctg     3660

aaaggaaata cacttctttt gaacatcccc actaggttct tttccattgt caataaggag     3720

catcagccag tgaatctgtt tcaggtttcc attctgcaga actcctccaa agcatgtgct     3780

agtggcaaga cagtggttct tatgatgttt tcccttaact tttccttgta tgttcttggg     3840

tggttcctaa gggaaaggga agcacatgat catgggaatg atagcccaga acaaaaagaa     3900

atcttgtctt accacagtgt tttataggag agattgggag aaatcatcct gttttctctg     3960

tgacctgatt tcagaagaga ctgatccaaa aattataacg gcagggaacc tagtgcattt     4020

ggcactgaga tttaaatgca accagaattg tcctcaaggc ccagccataa aagcattgtc     4080

tctctcgacc ttctggtatc ttgttagaga gcttttcact gtgaggaagt gtggaaaaat     4140

agctctgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtaatctgtt aggttgggga     4200

taggttttct gctagccaat attaaaagag acctgcaata aaaaaattac cctgatctga     4260

tagaaagcaa gtgtttttgt atgtgtgggt gaatgtgtgt tcatgcccgt atatgtctac     4320

acacagatga caaattatat ttgaaatcgt tggaaaataa attcagatca aaatgccttt     4380

caggcccatt acctagaaat ctatcttaaa acctgggtat gttcctaagg tcatttcttt     4440

gcttatgcta aattaattac aattatgaat ggaggatatt ctactgtact tttttaaaaa     4500

gaaactattt ttgtgtttga aagtgaaacc aacatccaga tctatagcag agtccttatt     4560

cttctcataa atctttttac tttggctaca aatagatgat ggtatgattc tattatatat     4620

tttatataaa atccatccaa attaagtttt gggtaagtgt gttgtttaat ctgaactata     4680

gtaacttaat actctaaaca atagttcact ccatttggtc ctttctccac agatgtaatt     4740

atgttttcaa ctcaggaact atggcaagga actttcccca gatcaaattc tattaacgct     4800

gagatacaag tcatccatgc acagccacta tcataccctt tattctcact gaaaggcaga     4860

actcagaacc tgttatttta tgtctgtaat catgtacttt ggcatctttt ggaggaaagg     4920

ggcaggataa ctcactggaa tgtacagtat tttgctagtg catttcaagg aatggaatct     4980

tctccagtat gaaattacca gatataaaat aatgtaatga tgctgaggat ataagctttt     5040

agaaggtaat ttgatggtat ttctttctcg aatgaaaagc tgctggttta ccctcaaccc     5100

tattcattag cattaccatg agtgaattta tatctaatta tttccacttg ccctgttctc     5160

ttcacaccaa ggaagctcca gatccagtat cttgtttggc ctcaaaacag aagcagcttc     5220

ttttgtctcc cagcagtagt gagccactca gtctcttcca caggaagttt ggagcctaca     5280

ttccttgagt caggagctta ttacagaaaa accccgtttc cctgaacttt tggctaacag     5340

aaattaattt aactgacatg catattgatt ctgaaatttt tttcctaagt ttttttcatt     5400

tttttgaatg agttttttaa attttttaga tgaccaaaac ttgcagggca ggggatgccc     5460

agaagagtgg tgagatagta aaacacttat tccctcatcc tttcaggttt tcaggttgcc     5520

catttatatt catttacatg tcatttgact gtctcacttt ttacccagaa cagtaacaac     5580

ccacaccgtc ttccttcagg gatttccaac tggcactctg tgggtgctac acagaatgca     5640

atttaatgga tatttctcag cctggttcag aataaattga tcctttgatc ccagaaagta     5700

tatactgaag tgtgggataa agattatgat taggggaggg ttggagacaa aagctgtaaa     5760

ttactatggc tgatttattt ctactatata catatatatt ttttgctttt gtatatccta     5820

tataggaaac taagcattgt atttttttta acaaatctaa aaaagcacta tgaactacag     5880

gtgtttgact ttcaaaatat attttgtatt gttaatatct tcacattgtg tgaatactgg     5940

aagctgcaga tctttgctag gacgcaataa atttatatac tttttgaggg gttcttctgg     6000

ggtgctaatc aggcccctgt tatgcttagg gggagccctg gtgctacttg cttgaagttt     6060

tcagtgtaag taccctgatg ccttttggac cttgggatca gatcaagagt tttggagatc     6120

aggtaccaag gaaataagga cagtctagct gcctcaagtg aggggccctt tgcatagctc     6180

tccttccccc tcactgaagc tgggtagcct attggggttg agagggaaaa tgtgaaatct     6240

cagaatttat ctcccttaga agagagccag taacttatgt acaaggatga aagaaaggtc     6300

gcagcagtag ctttggggaa agggaggaag atatggcact tctccaaccc cggaaaacat     6360

tgcttttgaa aactgctgat aaaatatgag ccggttatta cttctgtttg ggagactgtg     6420

ctctctgtgg tgcctctctt ggctctactc cacagatacc agacctcttc taagaggatg     6480

agcagaccag ctttgaggtt gacctgtttc tctttgtctg ccttcccaaa acaccagccc     6540

ccaggaagac attaagcagc cttaagctta aattcctact ccctcttcca aatttggctc     6600

acttgcctta gatccaaggc agggaaagga aaagaagggg ggtctctggc tttattactc     6660

ccctaagtct ttactctgac ttccccaaac ccagaaagat tttctccaca gtgttcattt     6720

gaaagaggag tattttgtcc cattttcccc ttcctcatta tcaaacagcc ccagtcttcc     6780

ttgtctctgc taagaaagta gaggcatgat gatctgcctc tcaactgccc taagtcctag     6840

ctaagtatca ggggaaaaaa aaaaaaaaaa agcctaacaa atgggattag actagggctg     6900

caagtagtga ggattttgtt gatacctctg ctgggatgtg tgctttccca tatcttgcct     6960

tcaggaatta cactgtgcct tttccccagg gatatgggct ctgtctaccc agtgctccag     7020

tttcccggta actgctcttg aacattgtgg acaagggcag gtcttcatat ttttgatcat     7080

ccctttctcc cagtgaaatc ccatagccct tacctagagt ctagggcaca aagacttcgg     7140

ggaagataca ctgagattga cctgaggaga catctacaca caccagtggc agctgcccca     7200

gggcctgctt ccccttccta agtctgtcat cctctggaag ggatgggtgg tgctccaatc     7260

tctggtgcct aaaaacccaa gtttatttct ctcttaacac tggcaataac cagtccacac     7320

cactgttgcc ttttaaaacc tcttaataat ctcatgctgt gtttgttttg attccaatcc     7380

aattatcacc agggctgtgt gggtaaatgc ttttaaatgc tctctcatct tgttcttccc     7440

cctcaccccc cactcttagg tatgtatgat gctaatcttg tccctaagta agtttcttcc     7500

tgctcctttt gtatcttcct ttcttgtctt tcctcctacc ttttgtctct tggtgttttg     7560

ggactttttt tttttttttt ttggcctttt gtacaaagat tagtttcaat gtagtctgta     7620

gcctcctttg taaaccaatt aaaaagtttt ttaataaaaa aaaaaaa                   7667


<210>  1319
<211>  3727
<212>  DNA
<213>  homo sapiens

<400>  1319
ttccgcggag gtcctgcctc tccctgcgga cgggcgctga ttggcccgtt tgaaatgcgc       60

caggcgggag ctcacctggg ctcttagcgt cgccgccggc ttcgcagagc accgcgcctt      120

agccgcgaag ttctagttct tgctgccggt cctaacgtcc cgcagtcttc gccagccagc      180

cgtcccgcat gcgcgtttgg gcggcgtgga gcctgctgcc atgaagtcag cgagagctaa      240

gacaccccgg aaacctaccg tgaaaaaagg gtcccaaacg aaccttaaag acccagttgg      300

ggtatactgt agggtgcgcc cactgggctt tcctgatcaa gagtgttgca tagaagtgat      360

caataataca actgttcagc ttcatactcc tgagggctac agactcaacc gaaatggaga      420

ctataaggag actcagtatt catttaaaca agtatttggc actcacacca cccagaagga      480

actctttgat gttgtggcta atcccttggt caatgacctc attcatggca aaaatggtct      540

tctttttaca tatggtgtga cgggaagtgg aaaaactcac acaatgactg gttctccagg      600

ggaaggaggg ctgcttcctc gttgtttgga catgatcttt aacagtatag ggtcatttca      660

agctaaacga tatgttttca aatctaatga taggaatagt atggatatac agtgtgaggt      720

tgatgcctta ttagaacgtc agaaaagaga agctatgccc aatccaaaga cttcttctag      780

caaacgacaa gtagatccag agtttgcaga tatgataact gtacaagaat tctgcaaagc      840

agaagaggtt gatgaagata gtgtctatgg tgtatttgtc tcttatattg aaatatataa      900

taattacata tatgatctat tggaagaggt gccgtttgat cccataaaac ccaaacctcc      960

acaatctaaa ttgcttcgtg aagataagaa ccataacatg tatgttgcag gatgtacaga     1020

agttgaagtg aaatctactg aggaggcttt tgaagttttc tggagaggcc agaaaaagag     1080

acgtattgct aatacccatt tgaatcgtga gtccagccgt tcccatagcg tgttcaacat     1140

taaattagtt caggctccct tggatgcaga tggagacaat gtcttacagg aaaaagaaca     1200

aatcactata agtcagttgt ccttggtaga tcttgctgga agtgaaagaa ctaaccggac     1260

cagagcagaa gggaacagat tacgtgaagc tggtaatatt aatcagtcac taatgacgct     1320

aagaacatgt atggatgtcc taagagagaa ccaaatgtat ggaactaaca agatggttcc     1380

atatcgagat tcaaagttaa cccatctgtt caagaactac tttgatgggg aaggaaaagt     1440

gcggatgatc gtgtgtgtga accccaaggc tgaagattat gaagaaaact tgcaagtcat     1500

gagatttgcg gaagtgactc aagaagttga agtagcaaga cctgtagaca aggcaatatg     1560

tggtttaacg cctgggagga gatacagaaa ccagcctcga ggtccagttg gaaatgaacc     1620

attggttact gacgtggttt tgcagagttt tccacctttg ccatcatgcg aaattttgga     1680

tatcaacgat gagcagacac ttccaaggct gattgaagcc ttagagaaac gacataactt     1740

acgacaaatg atgattgatg agtttaacaa acaatctaat gcttttaaag ctttgttaca     1800

agaatttgac aatgctgttt taagtaaaga aaaccacatg caagggaaac taaatgaaaa     1860

ggagaagatg atctcaggac agaaattgga aatagaacga ctggaaaaga aaaacaaaac     1920

tttagaatat aagattgaga ttttagagaa aacaactact atctatgagg aagataaacg     1980

caatttgcaa caggaacttg aaactcagaa ccagaaactt cagcgacagt tttctgacaa     2040

acgcagatta gaagccaggt tgcaaggcat ggtgacagaa acgacaatga agtgggagaa     2100

agaatgtgag cgtagagtgg cagccaaaca gctggagatg cagaataaac tctgggttaa     2160

agatgaaaag ctgaaacaac tgaaggctat tgttaccgaa cctaaaactg agaagccaga     2220

gagaccctct cgggagcgag atcgagaaaa agttactcaa agatctgttt ctccatcacc     2280

tgtgcctctt tctagtaact atattgctca gatttccaac ggccagcaac tcatgagcca     2340

gccacagcta cataggcgct ctaactcttg cagcagcatt tctgtagctt cctgtatttc     2400

ggaatgggag cagaaaattc ctacgtacaa cacacctctc aaagtcacat ctattgcaag     2460

gcgtaggcag caggagccag gacaaagcaa aacttgtatc gtgtcagaca gaaggcgagg     2520

gatgtactgg actgaaggca gggaggtggt tcctacattc agaaatgaga tagaaataga     2580

agaggatcat tgcggcaggt tactctttca acctgatcag aacgcaccac caattcgtct     2640

ccgacacaga cgatcacgct ctgcaggaga cagatgggta gatcataagc ccgcctctaa     2700

catgcaaact gaaacagtca tgcagccaca tgtccctcat gccatcacag tatctgttgc     2760

aaatgaaaag gcactagcta agtgtgagaa gtacatgctg acccaccagg aactagcctc     2820

cgatggggag attgaaacta aactaattaa gggtgatatt tataaaacaa ggggtggtgg     2880

acaatctgtt cagtttactg atattgagac tttaaagcaa gaatcaccaa atggtagtcg     2940

aaaacgaaga tcttccacag tagcacctgc ccaaccagat ggtgcagagt ctgaatggac     3000

cgatgtagaa acaaggtgtt ctgtggctgt ggagatgaga gcaggatccc agctgggacc     3060

tggatatcag catcacgcac aacccaagcg caaaaagcca tgaactgaca gtcccagtac     3120

tgaaagaaca ttttcatttg tgtggatgat ttctcgaaag ccatgccaga agcagtcttc     3180

caggtcatct tgtagaactc cagctttgtt gaaaatcacg gacctcagct acatcataca     3240

ctgacccaga gcaaagcttt ccctatggtt ccaaagacaa ctagtattca acaaaccttg     3300

tatagtatat gttttgccat atttaatatt aatagcagag gaagactcct tttttcatca     3360

ctgtatgaat tttttataat gtttttttaa aatatatttc atgtatactt ataaactaat     3420

tcacacaagt gtttgtctta gatgattaag gaagactata tctagatcat gtctgatttt     3480

ttattgtgac ttctccagcc ctggtctgaa tttcttaagg ttttataaac aaatgctgct     3540

atttattagc tgcaagaatg cactttagaa ctatttgaca attcagactt tcaaaataaa     3600

gatgtaaatg actggccaat aataaccatt ttaggaaggt gttttgaatt ctgtatgtat     3660

atattcactt tctgacattt agatatgcca aaagaattaa aatcaaaagc actaagaaat     3720

acaaaaa                                                               3727


<210>  1320
<211>  3415
<212>  DNA
<213>  homo sapiens

<400>  1320
ttccgcggag gtcctgcctc tccctgcgga cgggcgctga ttggcccgtt tgaaatgcgc       60

caggcgggag ctcacctggg ctcttagcgt cgccgccggc ttcgcagagc accgcgcctt      120

agccgcgaag ttctagttct tgctgccggt cctaacgtcc cgcagtcttc gccagccagc      180

cgtcccgcat gcgcgtttgg gcggcgtgga gcctgctgcc atgaagtcag cgagagctaa      240

gacaccccgg aaacctaccg tgaaaaaagg gtcccaaacg aaccttaaag acccagttgg      300

ggtatactgt agggtgcgcc cactgggctt tcctgatcaa gagtgttgca tagaagtgat      360

caataataca actgttcagc ttcatactcc tgagggctac agactcaacc gaaatggaga      420

ctataaggag actcagtatt catttaaaca agtatttggc actcacacca cccagaagga      480

actctttgat gttgtggcta atcccttggt caatgacctc attcatggca aaaatggtct      540

tctttttaca tatggtgtga cgggaagtgg aaaaactcac acaatgactg gttctccagg      600

ggaaggaggg ctgcttcctc gttgtttgga catgatcttt aacagtatag ggtcatttca      660

agctaaacga tatgttttca aatctaatga taggaatagt atggatatac agtgtgaggt      720

tgatgcctta ttagaacgtc agaaaagaga agctatgccc aatccaaaga cttcttctag      780

caaacgacaa gtagatccag agtttgcaga tatgataact gtacaagaat tctgcaaagc      840

agaagaggtt gatgaagata gtgtctatgg tgtatttgtc tcttatattg aaatatataa      900

taattacata tatgatctat tggaagaggt gccgtttgat cccataaaac ccaaacctcc      960

acaatctaaa ttgcttcgtg aagataagaa ccataacatg tatgttgcag gatgtacaga     1020

agttgaagtg aaatctactg aggaggcttt tgaagttttc tggagaggcc agaaaaagag     1080

acgtattgct aatacccatt tgaatcgtga gtccagccgt tcccatagcg tgttcaacat     1140

taaattagtt caggctccct tggatgcaga tggagacaat gtcttacagg aaaaagaaca     1200

aatcactata agtcagttgt ccttggtaga tcttgctgga agtgaaagaa ctaaccggac     1260

cagagcagaa gggaacagat tacgtgaagc tggtaatatt aatcagtcac taatgacgct     1320

aagaacatgt atggatgtcc taagagagaa ccaaatgtat ggaactaaca agatggttcc     1380

atatcgagat tcaaagttaa cccatctgtt caagaactac tttgatgggg aaggaaaagt     1440

gcggatgatc gtgtgtgtga accccaaggc tgaagattat gaagaaaact tgcaagtcat     1500

gagatttgcg gaagtgactc aagaagttga agtagcaaga cctgtagaca aggcaatatg     1560

tggtttaacg cctgggagga gatacagaaa ccagcctcga ggtccagttg gaaatgaacc     1620

attggttact gacgtggttt tgcagagttt tccacctttg ccatcatgcg aaattttgga     1680

tatcaacgat gagcagacac ttccaaggct gattgaagcc ttagagaaac gacataactt     1740

acgacaaatg atgattgatg agtttaacaa acaatctaat gcttttaaag ctttgttaca     1800

agaatttgac aatgctgttt taagtaaaga aaaccacatg caagggaaac taaatgaaaa     1860

ggagaagatg atctcaggac agaaattgga aatagaacga ctggaaaaga aaaacaaaac     1920

tttagaatat aagattgaga ttttagagaa aacaactact atctatgagg aagataaacg     1980

caatttgcaa caggaacttg aaactcagaa ccagaaactt cagcgacagt tttctgacaa     2040

acgcagatta gaagccaggt tgcaaggcat ggtgacagaa acgacaatga agtgggagaa     2100

agaatgtgag cgtagagtgg cagccaaaca gctggagatg cagaataaac tctgggttaa     2160

agatgaaaag ctgaaacaac tgaaggctat tgttaccgaa cctaaaactg agaagccaga     2220

gagaccctct cgggagcgag atcgagaaaa agttactcaa agatctgttt ctccatcacc     2280

tgtgccttta ctctttcaac ctgatcagaa cgcaccacca attcgtctcc gacacagacg     2340

atcacgctct gcaggagaca gatgggtaga tcataagccc gcctctaaca tgcaaactga     2400

aacagtcatg cagccacatg tccctcatgc catcacagta tctgttgcaa atgaaaaggc     2460

actagctaag tgtgagaagt acatgctgac ccaccaggaa ctagcctccg atggggagat     2520

tgaaactaaa ctaattaagg gtgatattta taaaacaagg ggtggtggac aatctgttca     2580

gtttactgat attgagactt taaagcaaga atcaccaaat ggtagtcgaa aacgaagatc     2640

ttccacagta gcacctgccc aaccagatgg tgcagagtct gaatggaccg atgtagaaac     2700

aaggtgttct gtggctgtgg agatgagagc aggatcccag ctgggacctg gatatcagca     2760

tcacgcacaa cccaagcgca aaaagccatg aactgacagt cccagtactg aaagaacatt     2820

ttcatttgtg tggatgattt ctcgaaagcc atgccagaag cagtcttcca ggtcatcttg     2880

tagaactcca gctttgttga aaatcacgga cctcagctac atcatacact gacccagagc     2940

aaagctttcc ctatggttcc aaagacaact agtattcaac aaaccttgta tagtatatgt     3000

tttgccatat ttaatattaa tagcagagga agactccttt tttcatcact gtatgaattt     3060

tttataatgt ttttttaaaa tatatttcat gtatacttat aaactaattc acacaagtgt     3120

ttgtcttaga tgattaagga agactatatc tagatcatgt ctgatttttt attgtgactt     3180

ctccagccct ggtctgaatt tcttaaggtt ttataaacaa atgctgctat ttattagctg     3240

caagaatgca ctttagaact atttgacaat tcagactttc aaaataaaga tgtaaatgac     3300

tggccaataa taaccatttt aggaaggtgt tttgaattct gtatgtatat attcactttc     3360

tgacatttag atatgccaaa agaattaaaa tcaaaagcac taagaaatac aaaaa          3415


<210>  1321
<211>  4155
<212>  DNA
<213>  homo sapiens

<400>  1321
gcctgctcca agggaaggat caggagagaa gaaacgcaaa tcccagaacc gtgccaacat       60

ataaaacccc acattaaggg ttgtacagtg cactgggatt tctcaagtca cccgcttggt      120

cctcttccaa gtatacttta cttcctttca ttcctctcta aaactttttt aaaaactttc      180

actcctgctc taaaagttat cttggtttct tactctacct tatgcccctt gggcgaattt      240

tttcctctga ggagggaaga atagagttgc tgctgcagac acatcagatt ccctactggt      300

aacagctgga gtgcgtcacc tctgacaaaa ttctggggac gctgggaaca ctgaatcaac      360

atgggcaatg agaacagcac ctcggacaac cagaggactt tatcagctca gactccaagg      420

tccgcgcagc cacccgggaa cagtcagaat ataaaaagga agcagcagga cacgcccgga      480

agccctgacc acagagacgc gtccagttca cctgtggcag atgatatcat ccagcccgct      540

gcccccgcag acctggaaag cccaacctta gctgcctctt cctaccacgg tgatgttgtt      600

ggccaggtct ctacggatct gatagcccag aggagttccg attctgaaga ggcatttgag      660

accccggagt caacgacccc tgtcaaagct ccgccagctc cacccccacc accccccgaa      720

gtcatcccag aacccgaggt cagcacacag ccacccccgg aagaaccagg atgtggttct      780

gagacagtcc ctgtccctga tggcccacgg agcgactcgg tggaaggaag tcccttccgt      840

cccccgtcac actccttctc tgccgtcttc gatgaagaca agccgatagc cagcagtggg      900

acttacaact tggactttga caacattgag cttgtggata cctttcagac cttggagcct      960

cgtgcctcag acgctaagaa tcaggagggc aaagtgaaca cacggaggaa gtccacggat     1020

tccgtcccca tctctaagtc tacactgtcc cggtcgctca gcctgcaagc cagtgacttt     1080

gatggtgctt cttcctcagg caatcccgag gccgtggccc ttgccccaga tgcatatagc     1140

acgggttcca gcagtgcttc tagtaccctt aagcgaacta aaaaaccgag gccgccttcc     1200

ttaaaaaaga aacagaccac caagaaaccc acagagaccc ccccagtgaa ggagacgcaa     1260

caggagccag atgaagagag ccttgtcccc agtggggaga atctagcatc tgagacgaaa     1320

acggaatctg ccaagacgga aggtcctagc ccagccttat tggaggagac gccccttgag     1380

cccgctgtgg ggcccaaagc tgcctgccct ctggactcag agagtgcaga aggggttgtc     1440

cccccggctt ctggaggtgg cagagtgcag aactcacccc ctgtcgggag gaaaacgctg     1500

cctcttacca cggccccgga ggcaggggag gtaaccccat cggatagcgg ggggcaagag     1560

gactctccag ccaaagggct ctccgtaagg ctggagtttg actattctga ggacaagagt     1620

agttgggaca accagcagga aaacccccct cctaccaaaa agataggcaa aaagccagtt     1680

gccaaaatgc ccctgaggag gccaaagatg aaaaagacac ccgagaaact tgacaacact     1740

cctgcctcac ctcccagatc ccctgctgaa cccaatgaca tccccattgc taaaggtact     1800

tacacctttg atattgacaa gtgggatgac cccaatttta accctttttc ttccacctca     1860

aaaatgcagg agtctcccaa actgccccaa caatcataca actttgaccc agacacctgt     1920

gatgagtccg ttgacccctt taagacatcc tctaagaccc ccagctcacc ttctaaatcc     1980

ccagcctcct ttgagatccc agccagtgct atggaagcca atggagtgga cggggatggg     2040

ctaaacaagc ccgccaagaa gaagaagacg cccctaaaga ctgacacatt tagggtgaaa     2100

aagtcgccaa aacggtctcc tctctctgat ccaccttccc aggaccccac cccagctgct     2160

acaccagaaa caccaccagt gatctctgcg gtggtccacg ccacagatga ggaaaagctg     2220

gcggtcacca accagaagtg gacgtgcatg acagtggacc tagaggctga caaacaggac     2280

tacccgcagc cctcggacct gtccaccttt gtaaacgaga ccaaattcag ttcacccact     2340

gaggagttgg attacagaaa ctcctatgaa attgaatata tggagaaaat tggctcctcc     2400

ttacctcagg acgacgatgc cccgaagaag caggccttgt accttatgtt tgacacttct     2460

caggagagcc ctgtcaagtc atctcccgtc cgcatgtcag agtccccgac gccgtgttca     2520

gggtcaagtt ttgaagagac tgaagccctt gtgaacactg ctgcgaaaaa ccagcatcct     2580

gtcccacgag gactggcccc taaccaagag tcacacttgc aggtgccaga gaaatcctcc     2640

cagaaggagc tggaggccat gggcttgggc accccttcag aagcgattga aattacagct     2700

cccgagggct cctttgcctc tgctgacgcc ctcctcagca ggctagctca ccccgtctct     2760

ctctgtggtg cacttgacta tctggagccc gacttagcag aaaagaaccc cccactattc     2820

gctcagaaac tccaggagga gttagagttt gccatcatgc ggatagaagc cctgaagctg     2880

gccaggcaga ttgctttggc ttcccgcagc caccaggatg ccaagagaga ggctgctcac     2940

ccaacagacg tctccatctc caaaacagcc ttgtactccc gcatcgggac cgctgaggtg     3000

gagaaacctg caggccttct gttccagcag cccgacctgg actctgccct ccagatcgcc     3060

agagcagaga tcataaccaa ggagagagag gtctcagaat ggaaagataa atatgaagaa     3120

agcaggcggg aagtgatgga aatgaggaaa atagtggccg agtatgagaa gaccatcgct     3180

cagatgatag aggacgaaca gagagagaag tcagtctccc accagacggt gcagcagctg     3240

gttctggaga aggagcaagc cctggccgac ctgaactccg tggagaagtc tctggccgac     3300

ctcttcagaa gatatgagaa gatgaaggag gtcctagaag gcttccgcaa gaatgaagag     3360

gtgttgaaga gatgtgcgca ggagtacctg tcccgggtga agaaggagga gcagaggtac     3420

caggccctga aggtgcacgc ggaggagaaa ctggacaggg ccaatgctga gattgctcag     3480

gttcgaggca aggcccagca ggagcaagcc gcccaccagg ccagcctgcg gaaggagcag     3540

ctgcgagtgg acgccctgga aaggacgctg gagcagaaga ataaagaaat agaagaactc     3600

accaagattt gtgacgaact gattgccaaa atggggaaaa gctaactctg aaccgaatgt     3660

tttggactta actgttgcgt gcaatatgac cgtcggcaca ctgctgttcc tccagttcca     3720

tggacaggtt ctgttttcac tttttcgtat gcactactgt atttcctttc taaataaaat     3780

tgatttgatt gtatgcagta ctaaggagac tatcagaatt tcttgctatt ggtttgcatt     3840

ttcctagtat aattcatagc aagttgacct cagagttcct gtatcaggga gattgtctga     3900

ttctctaata aaagacacat tgctgacctt ggccttgccc tttgtacaca agttcccagg     3960

gtgagcagct tttggattta atatgaacat gtacagcgtg catagggact cttgccttaa     4020

ggagtgtaaa cttgatctgc atttgctgat ttgtttttaa aaaaacaaga aatgcatgtt     4080

tcaaataaaa ttctctattg taaataaaat tttttctttg gatcttggca ataaaaaaaa     4140

aaaaaaaaaa aaaaa                                                      4155


<210>  1322
<211>  4090
<212>  DNA
<213>  homo sapiens

<400>  1322
gcgggcggtc ccggcgaggc gggaggggcc ggggcagagg gagggtcttc gcctccccac       60

ccccagcccc gtttccggag cccgcgatgg agctttgtga agatgcaggc gttggggctg      120

ctcggcgatg atgacatcat cgtgtcacac acaggagccg gctgccgggg ggtttaagag      180

aagagccttt cggaccacac cggcgctcac gctcataccc gcacgccccg ggcagagccg      240

cgcacgccgg ccacactcgg gcgcgcgccg gccacactcg cgcgcacaca tacgcggcgc      300

tcgccccccg gcccccggct cgggccgcga gtcgcagctc cctgccgccg ctcccgccgc      360

cacggatgcc cgcagctgct cccctctgca gtgcagcaac cccggccgcc ggccggctcg      420

ccccggctcc cggctgcagg aatcgcgcca ggacgctggc cccgctcgcg gctagcttgc      480

acgccagggc acagcgagga tgggagggtc gcagtccctg cagccagccc cagccagcga      540

cctgaacctg gaggcttccg aggcaatgag ttccgattct gaagaggcat ttgagacccc      600

ggagtcaacg acccctgtca aagctccgcc agctccaccc ccaccacccc ccgaagtcat      660

cccagaaccc gaggtcagca cacagccacc cccggaagaa ccaggatgtg gttctgagac      720

agtccctgtc cctgatggcc cacggagcga ctcggtggaa ggaagtccct tccgtccccc      780

gtcacactcc ttctctgccg tcttcgatga agacaagccg atagccagca gtgggactta      840

caacttggac tttgacaaca ttgagcttgt ggataccttt cagaccttgg agcctcgtgc      900

ctcagacgct aagaatcagg agggcaaagt gaacacacgg aggaagtcca cggattccgt      960

ccccatctct aagtctacac tgtcccggtc gctcagcctg caagccagtg actttgatgg     1020

tgcttcttcc tcaggcaatc ccgaggccgt ggcccttgcc ccagatgcat atagcacggg     1080

ttccagcagt gcttctagta cccttaagcg aactaaaaaa ccgaggccgc cttccttaaa     1140

aaagaaacag accaccaaga aacccacaga gaccccccca gtgaaggaga cgcaacagga     1200

gccagatgaa gagagccttg tccccagtgg ggagaatcta gcatctgaga cgaaaacgga     1260

atctgccaag acggaaggtc ctagcccagc cttattggag gagacgcccc ttgagcccgc     1320

tgtggggccc aaagctgcct gccctctgga ctcagagagt gcagaagggg ttgtcccccc     1380

ggcttctgga ggtggcagag tgcagaactc accccctgtc gggaggaaaa cgctgcctct     1440

taccacggcc ccggaggcag gggaggtaac cccatcggat agcggggggc aagaggactc     1500

tccagccaaa gggctctccg taaggctgga gtttgactat tctgaggaca agagtagttg     1560

ggacaaccag caggaaaacc cccctcctac caaaaagata ggcaaaaagc cagttgccaa     1620

aatgcccctg aggaggccaa agatgaaaaa gacacccgag aaacttgaca acactcctgc     1680

ctcacctccc agatcccctg ctgaacccaa tgacatcccc attgctaaag gtacttacac     1740

ctttgatatt gacaagtggg atgaccccaa ttttaaccct ttttcttcca cctcaaaaat     1800

gcaggagtct cccaaactgc cccaacaatc atacaacttt gacccagaca cctgtgatga     1860

gtccgttgac ccctttaaga catcctctaa gacccccagc tcaccttcta aatccccagc     1920

ctcctttgag atcccagcca gtgctatgga agccaatgga gtggacgggg atgggctaaa     1980

caagcccgcc aagaagaaga agacgcccct aaagactgac acatttaggg tgaaaaagtc     2040

gccaaaacgg tctcctctct ctgatccacc ttcccaggac cccaccccag ctgctacacc     2100

agaaacacca ccagtgatct ctgcggtggt ccacgccaca gatgaggaaa agctggcggt     2160

caccaaccag aagtggacgt gcatgacagt ggacctagag gctgacaaac aggactaccc     2220

gcagccctcg gacctgtcca cctttgtaaa cgagaccaaa ttcagttcac ccactgagga     2280

gttggattac agaaactcct atgaaattga atatatggag aaaattggct cctccttacc     2340

tcaggacgac gatgccccga agaagcaggc cttgtacctt atgtttgaca cttctcagga     2400

gagccctgtc aagtcatctc ccgtccgcat gtcagagtcc ccgacgccgt gttcagggtc     2460

aagttttgaa gagactgaag cccttgtgaa cactgctgcg aaaaaccagc atcctgtccc     2520

acgaggactg gcccctaacc aagagtcaca cttgcaggtg ccagagaaat cctcccagaa     2580

ggagctggag gccatgggct tgggcacccc ttcagaagcg attgaaatta cagctcccga     2640

gggctccttt gcctctgctg acgccctcct cagcaggcta gctcaccccg tctctctctg     2700

tggtgcactt gactatctgg agcccgactt agcagaaaag aaccccccac tattcgctca     2760

gaaactccag gaggagttag agtttgccat catgcggata gaagccctga agctggccag     2820

gcagattgct ttggcttccc gcagccacca ggatgccaag agagaggctg ctcacccaac     2880

agacgtctcc atctccaaaa cagccttgta ctcccgcatc gggaccgctg aggtggagaa     2940

acctgcaggc cttctgttcc agcagcccga cctggactct gccctccaga tcgccagagc     3000

agagatcata accaaggaga gagaggtctc agaatggaaa gataaatatg aagaaagcag     3060

gcgggaagtg atggaaatga ggaaaatagt ggccgagtat gagaagacca tcgctcagat     3120

gatagaggac gaacagagag agaagtcagt ctcccaccag acggtgcagc agctggttct     3180

ggagaaggag caagccctgg ccgacctgaa ctccgtggag aagtctctgg ccgacctctt     3240

cagaagatat gagaagatga aggaggtcct agaaggcttc cgcaagaatg aagaggtgtt     3300

gaagagatgt gcgcaggagt acctgtcccg ggtgaagaag gaggagcaga ggtaccaggc     3360

cctgaaggtg cacgcggagg agaaactgga cagggccaat gctgagattg ctcaggttcg     3420

aggcaaggcc cagcaggagc aagccgccca ccaggccagc ctgcggaagg agcagctgcg     3480

agtggacgcc ctggaaagga cgctggagca gaagaataaa gaaatagaag aactcaccaa     3540

gatttgtgac gaactgattg ccaaaatggg gaaaagctaa ctctgaaccg aatgttttgg     3600

acttaactgt tgcgtgcaat atgaccgtcg gcacactgct gttcctccag ttccatggac     3660

aggttctgtt ttcacttttt cgtatgcact actgtatttc ctttctaaat aaaattgatt     3720

tgattgtatg cagtactaag gagactatca gaatttcttg ctattggttt gcattttcct     3780

agtataattc atagcaagtt gacctcagag ttcctgtatc agggagattg tctgattctc     3840

taataaaaga cacattgctg accttggcct tgccctttgt acacaagttc ccagggtgag     3900

cagcttttgg atttaatatg aacatgtaca gcgtgcatag ggactcttgc cttaaggagt     3960

gtaaacttga tctgcatttg ctgatttgtt tttaaaaaaa caagaaatgc atgtttcaaa     4020

taaaattctc tattgtaaat aaaatttttt ctttggatct tggcaataaa aaaaaaaaaa     4080

aaaaaaaaaa                                                            4090


<210>  1323
<211>  3618
<212>  DNA
<213>  homo sapiens

<400>  1323
aaattttcct ccaggctgtc cttggagaat tccaccctct ttcattctgg ggagaagaag       60

ttaaaattag ggccagccct gcgggactga catgccagat gcagggaagc tgtccccaga      120

aataagcgag ttcccaccgc ggctgggcgg ggcgggagcc tcgggtccca acccagcgga      180

gggactcctg gaaggcctgc cccttccaag tgtctgcaag ggctctggtc ccaagcttta      240

aaatcctgag cgaaggcact gcgggccgac ctctcctctc ccagccagtc gtggctggcc      300

tttcaaagtg tgcagttgtc tcctccctgt ccagccccat cgtcgcccag gaccagctgg      360

gccgcggtct gacctgaggc tgctgctcag cgccggggcg ctggcgctct ccattcgagc      420

accttccagc ataccgctcg gctccgggag ccgctctgca aagttgggca gctcagagcg      480

caagctttgc ctctcgactt ctccctcctt gggtccccgg cgcccccgcc tcccacgatc      540

cctttcacta ggagcagcca gtcccagcgg gctggcaact tgcacccctt cctagtcatc      600

ctccctgaaa cgcgaccatg ctgttaaggg gcgtcctcct ggcgttgcaa gccctgcagc      660

tcgccggtgc cctcgacctg cccgctgggt cctgtgcctt tgaagagagc acttgcggct      720

ttgactccgt gttggcctct ctgccgtgga ttttaaatga ggaaggccat tacatttatg      780

tggatacctc ctttggcaag cagggggaga aagctgtgct gctaagtcct gacttacagg      840

ctgaggaatg gagctgcctc cgtttggtct accagataac cacatcttcg gagtctctgt      900

cagatcccag ccagctgaac ctctacatga gatttgaaga tgaaagcttt gatcgcttgc      960

tttggtcagc taaggaacct tcagacagct ggctcatagc cagcttggat ttgcaaaaca     1020

gttccaagaa attcaagatt ttaatagaag gtgtactagg acagggaaac acagccagca     1080

tcgcactatt tgaaatcaag atgacaaccg gctactgtat tgaatgtgac tttgaagaaa     1140

atcatctctg tggctttgtg aaccgctgga atcccaatgt gaactggttt gttggaggag     1200

gaagtattcg gaatgtccac tccattctcc cacaggatca caccttcaag agtgaactgg     1260

gccactacat gtacgtggac tcagtttatg tgaagcactt ccaggaggtg gcacagctca     1320

tctccccgtt gaccacggcc cccatggctg gctgcctgtc attttattac cagatccagc     1380

aggggaatga caatgtcttt tccctttaca ctcgggatgt ggctggcctt tacgaggaaa     1440

tctggaaagc agacaggcca gggaatgctg cctggaacct tgcggaggtc gagttcagtg     1500

ctccttaccc catggaggtt atttttgaag ttgctttcaa tggtcccaag ggaggttatg     1560

ttgccctgga tgatatttca ttctctcctg ttcactgcca gaatcagaca gaacttctgt     1620

tcagtgccgt ggaagccagc tgcaattttg agcaagatct ctgcaacttt taccaagata     1680

aagaaggtcc aggttggacc cgagtgaaag taaaaccaaa catgtatcgg gctggagacc     1740

acactacagg cttagggtat tacctgctag ccaacacaaa gttcacatct cagcctggct     1800

acattggaag gctctatggg ccctccctac caggaaactt gcagtattgt ctgcgttttc     1860

attatgccat ctatggattt ttaaaaatga gtgacaccct agcagtttac atctttgaag     1920

agaaccatgt ggttcaagag aagatctggt ctgtgttgga gtccccaagg ggtgtttgga     1980

tgcaagctga aatcaccttt aagaagccca tgcctaccaa ggtggttttc atgagcctat     2040

gcaaaagttt ctgggactgt gggcttgtag ccctggatga cattacaata caattgggaa     2100

gctgctcatc ttcagagaaa cttccacctc cacctggaga gtgtactttc gagcaagatg     2160

aatgtacatt tactcaggag aaaagaaacc ggagcagctg gcacaggagg aggggagaaa     2220

ctcccacttc ctacacagga ccaaagggag atcacactac tggggtaggc tactacatgt     2280

acattgaggc ctcccatatg gtgtatggac aaaaagcacg cctcttgtcc aggcctctgc     2340

gaggagtctc tggaaaacac tgcttgacct ttttctacca catgtatgga gggggcactg     2400

gcctgctgag tgtttatctg aaaaaggaag aagacagtga agagtccctc ttatggagga     2460

gaagaggtga acagagcatt tcctggctac gagcactgat tgaatacagc tgtgagaggc     2520

aacaccagat aatttttgaa gccattcgag gagtatcaat aagaagtgat attgccattg     2580

atgatgttaa atttcaggca ggaccctgtg gagaaatgga agatacaact caacaatcat     2640

caggatattc tgaggactta aatgaaattg agtattaaga aatgatctgc attggattta     2700

ctagacgaaa accatacctc tcttcaatca aaatgaaaac aaagcaaatg aatactggac     2760

agtcttaaca attttataag ttataaaatg actttagagc accctccttc attacttttg     2820

caaaaacata ctgactcagg gctctttttt tctttttgca tatgacaact gttactagaa     2880

atacaggcta ctggttttgc atagatcatt catcttaatt ttggtaccag ttaaaaatac     2940

aaatgtacta tattgtagtc attttaaagt acacaaaggg cacaatcaaa atgagatgca     3000

ctcatttaaa tctgcattca gtgaatgtat tgggagaaaa ataggtcttg caggtttcct     3060

tttgaatttt aagtatcata aatattttta aagtaaataa tacggggtgt cagtaatatc     3120

tgcagaatga atgcagtctt tcatgctaat gagttagtct ggaaaaataa agtcttattt     3180

tctatgtttt attcatagaa atggagtatt aatttttaat attttcacca tatgtgataa     3240

caaaggatct ttcatgaatg tccaagggta agtcagtatt aattaatgct gtattacaag     3300

gcaatgctac cttctttatt ccccctttga actacctttg aagtcactat gagcacatgg     3360

atagaaattt aacttttttt tgtaaagcaa gcttaaaatg tttatgtata catacccagc     3420

aacttttata aatgtgttaa acaattttac tgatttttat aataaatatt ttggtaagat     3480

tttgaataat atgaattcag gcagatatac taaactgctt ttatttactt gtttagaaaa     3540

ttgtatatat atgtttgtgt atcctaacag ctgctatgaa attataaaat tacctaataa     3600

aaataatttg aaaatctt                                                   3618


<210>  1324
<211>  7115
<212>  DNA
<213>  homo sapiens

<400>  1324
ctccctctcc tatcggagca caatgaaagc ctgtgtatcg ccgtgactcc gggcgcgagc       60

cagtgtcagc aaagcggcta acaacagacg agaaagagaa aggaaaatac aagctacttt      120

ttttttccat ctataaagcg gagcaaatac aggagataga accagattgc ttattgcgag      180

tccagaccct cagatccact ggccggggat ggaatgtaca aaagtggaca gaaaagtggc      240

tggacatgac tcggtgcaat ttgctggaag tttgtaagtt tgaccatcgt ttgtaaatta      300

ctctcggaag agtttgtctc tcttgatact gtattagaat agagccgggg gtgaggaata      360

gaaacgtaag cgggaaagaa aaaaatgtgt tgaaggatct ctctcagtgg ctagcgactt      420

aagattgctt ttcatttaag gctaggaaac cttagaggga gtgaggattt taccggtgat      480

tggattagct gaagaaaaaa gcatggtcca aaagtccaat tactgacatt gttaacagtt      540

gaaaagctgt ctccctcttt tgggagaaga caacatccta cagtacccca aagaggagaa      600

aacaccggag cgaaaggaaa gggaggaaaa attaaaagcc aaaagacagt ctcccttgat      660

ttttgcacat tttgaacagt gacttaaaca tcttctgaaa cagcactgtt ttgttttgtt      720

ttggtttttt atttaacctg aggaaaagtc aaggctgctg gttacataga catggtagaa      780

atgtgtttct ctgcagaaac atccccataa agaattgtcg gaaacaacta ggtgaggggg      840

agtcctctct attaatacct ctctcaatac cttttgctgt gtgtttctgt ctcttgctgg      900

acaatccctg aattcttgat ctaaccccca gatcgtgtgt ttacaaagta cctagtggct      960

cttgtcagct tggtggagga aaaaaaatcc accaactctg tccaacttct ccagagctgt     1020

caaatgcaat tagagtaagt taatcagggt ttgtttccaa cttatcctcc ccccagttgg     1080

tttctattct ttctccccac cctcttttta ctaactcccc tcccccacaa cttctccacg     1140

gctcccccac aacctctgaa gacctctatt catgtggccc tgaacactga gctcacattg     1200

tcaaaaacag acttgcctgc aatagccagc agtagcctct ttccacctca ccatcccaga     1260

ggcagcaatc attgtgtccg gtaagatggg ggacacagcg cccccgcagg cccccgcagg     1320

agggctaggg ggggcctctg gggcggggct ccttggaggg ggctcagtca ccccgagagt     1380

gcacagtgct atcgtggagc gcctccgggc tcggatcgct gtctgccgcc aacaccacct     1440

gagctgtgaa ggacgatatg aacgaggtag ggccgagagc tcagaccggg aaagagaaag     1500

caccttgcag ctcctgagcc ttgtacagca tggccagggg gcaaggaaag ctggcaaaca     1560

caccaaggcc accgccactg ctgccaccac tacagcccct ccaccgcccc ctgctgcccc     1620

tcctgcggcc tcccaagcag cagcaacagc agccccaccg cccccaccag actatcacca     1680

tcaccaccag cagcacctgc tgaacagtag caataatggt ggcagtggtg ggataaacgg     1740

agagcagcag ccgcccgctt caaccccagg ggaccagagg aactcagccc tgattgcgct     1800

ccagggttcc ttgaaaagaa aacaggtagt taacctatct cctgccaaca gcaagcgacc     1860

caatggcttt gtggacaact catttcttga tatcaaaaga attcgtgttg gggagaatct     1920

ctctgcagga caaggtggcc tccaaataaa caatggacaa agtcagatta tgtcagggac     1980

cttgcctatg agccaagcac ccctgcgaaa gactaacact ctgccatccc atacacattc     2040

tcctggcaat ggcctgttta acatgggctt aaaggaggta aagaaggagc caggagagac     2100

tctgtcttgc agtaagcaca tggatggcca aatgacccaa gagaatattt ttcctaatag     2160

gtacggagac gaccctggag aacaactgat ggatcctgag ctgcaggaac tgttcaatga     2220

actgaccaac atatctgtgc ctcccatgag tgaccttgaa ctggagaaca tgatcaatgc     2280

caccataaag caggatgacc catttaacat tgacttgggt cagcaaagcc agaggagcac     2340

acctaggccc tccttaccca tggagaaaat agtgatcaaa agtgaatact caccgggctt     2400

gactcagggc ccctcaggct ctcctcagct gaggccccca tcagctggcc ccgcattctc     2460

catggccaac tctgccctct ccacttcgtc tccaatccct tcagtccctc agagccaggc     2520

tcagcctcag acaggctccg gagcaagccg ggccttgcca agctggcagg aagtatccca     2580

tgcccagcag ctcaaacaga tagctgctaa tcgtcagcag catgcccgga tgcagcagca     2640

ccagcagcag caccagccta ccaactggtc agccttgccc tcttctgctg gaccatcacc     2700

aggtccattt gggcaggaga aaatccccag cccttctttt ggtcagcaga cattcagccc     2760

acagagctcc cccatgcctg gggtagctgg cggcagcggc cagtcgaaag taatggctaa     2820

ctacatgtac aaggccggcc cctcagccca gggtgggcac ctagatgtcc tcatgcagca     2880

aaagcctcag gatctcagtc gaagttttat taacaacccg cacccagcca tggagccccg     2940

tcagggcaac accaagcctt tgtttcattt taactcagat caagcgaacc agcagatgcc     3000

ttctgttttg ccttcccaga acaagccttc tctcctacac tacacccaac agcaacagca     3060

gcaacagcag cagcagcagc agcagcagca gcagcagcag cagcaacagc agcagcagca     3120

gcaacagcaa cagcaacagc aacagcagag ttcaatttca gctcaacaac agcaacagca     3180

gcagagctca atttcagccc aacagcagca gcagcagcaa caacagcagc agcagcagca     3240

acaacaacag caacaacagc agcagcagca gcagcaacaa ccatcttctc agcctgccca     3300

atctctacca agccagcctt tgctaaggtc acctttgcca cttcagcaaa agctcctact     3360

tcagcaaatg cagaatcagc ccattgcagg aatgggatac caagtctccc aacaacagag     3420

acaggatcaa cactctgtgg taggccagaa cacaggcccc agtccaagtc ctaacccctg     3480

ctcaaatcca aacactggaa gtggttacat gaactcccag caatcactgt tgaatcagca     3540

attgatggga aagaagcaga ctctacagag gcagatcatg gagcagaaac agcaacttct     3600

tctccagcag cagatgctgg ctgacgcgga gaaaattgct ccacaagatc agataaaccg     3660

acatttgtca aggccacctc cagattataa agaccaaaga agaaatgtgg gcaatatgca     3720

accaactgct cagtattctg gtggctcatc cacaataagc ttaaactcta accaggcttt     3780

ggcaaaccca gtttcaacac acaccatttt aactcccaat tccagcctcc tgtctacttc     3840

tcacgggaca agaatgccat cattatctac agcagttcag aatatgggga tgtatggaaa     3900

tctgccttgt aatcaaccta acacatacag tgtcacttca ggaatgaatc aattgaccca     3960

acagagaaac ccaaagcaat tgttagcaaa tcaaaacaac cctatgatgc cacggccacc     4020

taccttaggg ccaagtaata ataacaatgt agccactttt ggagctggat ctgttggtaa     4080

ttcacaacaa ttgagaccaa atttaaccca tagtatggca agcatgccac cacagagaac     4140

atcaaacgta atgatcacat ccaacacaac tgcaccaaac tgggcctctc aagaaggaac     4200

aagcaaacag caagaagccc tgacgtctgc aggagtccgc ttccccacag gtacacctgc     4260

agcctatacc ccaaatcagt cactgcaaca ggcagtaggt agccagcaat tttcccagag     4320

ggcagtggct cctcctaacc agttaacacc agcagtgcaa atgagaccca tgaaccaaat     4380

gagccaaaca ctaaatgggc aaaccatggg tcccctcagg ggtctgaatc tcagacccaa     4440

tcagctaagc acacagattt tgcctaattt gaatcagtca ggaacagggt tgaatcagtc     4500

gaggacgggc atcaaccagc caccatccct gacgcccagc aattttcctt cacccaacca     4560

aagttccagg gcttttcaag gaactgacca cagcagtgac ttagcttttg acttcctcag     4620

ccaacaaaat gataacatgg gccctgccct aaacagtgat gctgatttca ttgattcttt     4680

attgaagaca gagcctggta atgatgactg gatgaaagac atcaatcttg atgaaatctt     4740

ggggaacaat tcctaaagaa gaaagggaag acaatttaca aactccaagc actaaaaggc     4800

agtatattac agaaactctg tagaggctga actgttgatg ttcaggtgga ctacatgaag     4860

ataacatgct taaaaatgga aagcagaaag taactgcagt gatgaacatt ttggtccaaa     4920

ttcttgtttt aaatcttaca cctgaaagta aaatattggg atcacttttc cctgtctaaa     4980

ctccaggata cagtatccaa tttatccaaa cagaactgtg gtgtcaatgt gtaattaatt     5040

gtgtaaaata gccttcccaa gtttcttttt ccctggaaaa taaaaaaggt aatagaactt     5100

gtagtttatt taaaccccat gtcatgagga ggtactagtt ccaagcaaca aactccttaa     5160

tttgctctaa tagataggta tggtttaatc tttccattgt gtcttttcat ttaattttcc     5220

tgaagcttgc aggatagatt gaaatgttat aggtttgttt ggagtaacca aacagtatgc     5280

aaattaagaa aaagccagag aacctagaaa acatccagtg gattacagaa tttcttcccc     5340

atattcactc ctcactttta caattttccc acaatcctct acttcagtgg gatgctgtgt     5400

ctagtgatta aacaaaaata tagagctgtg caatttgatt ttggcttcca caacgaatat     5460

ctgaatccat tccaaatgaa attttagata taacaaagac ttgtcctaat catactgaaa     5520

tattggtgca cacctctctg cattagattt cactttttta aaaaacccag tggacattgc     5580

tataaataag atttatttgg ctacaaataa cctgggatgt tgcttattat gattgatgcc     5640

tgctggtttg ttcccaagct gagtgaaatt gaacctcgtc ctccctactc attttgatga     5700

ctgaggctgg tttataagaa aaggaagttt ggagaagaaa accgagatta gaaaatatca     5760

tgttttggtt ggagataaga accagggatg gcaagtacca gtgtgtacaa atgtatttca     5820

cggagtttga aggaacgcat aatcaagagg gaaaacaatt tgtccttcat tggacgtatt     5880

atttggattt gggtgagcaa caaaatggaa tgtggtctgt taggagcatt ctgtttgttc     5940

ttttgtccct gatgtgatga atcattgcca catgctagat ggactcttca tatccaggtt     6000

ttgtccctca gggctgagca ctgtattaaa gagtttttgt tgagtcattt aaccttagtg     6060

tccacatcca gatcagctgt aaaatgggga agacgtgtgc tgatttggaa tgaatgcaaa     6120

atatcactat cattttccta attacagagg agcaaaggtt atcttcagcc ctttcagttc     6180

tatgctcaca tattcaaata tcaaatgtaa tttagctgaa gttatttaat aatcaagtct     6240

ttcaatatct gttcaaagaa aaagaacaca ctttgaaaat tctgcaaagc tgtctcccag     6300

tctttaaaat gtctggaagc actctccttc tttacaatac caacatcact ggcccagaat     6360

cttccctgtg ctagtttgta aatataaata aattacttgt tttgtaaact tttgtaaaga     6420

atattttggt agaaatactt caaacatatt ctttgggtta tatttataca tatgtgaaat     6480

aaatatacta tcaaaaggtt atattttata caaaaagtaa attgctacct tttgtatgct     6540

aatatgcaaa gttttgtata atatgatggt ttatttttag ctctacactt aaaccatagg     6600

tggttgagtg ggaacttttg aaaactatca agaggcttgt tagacaaatt tatattctga     6660

aacctcaata agaaagcatt ccaggtttca atccttgttt tttgtcctgc tcccaaattc     6720

ttttttaaac ccatagttct tgtgtcttat ttgattcttc tgctgtgcac attgtattgg     6780

tccttgttgc atgtagtcta ctgtgtgttt tccgatttta taaggcagca tttctccata     6840

caaaaagaaa aaaaatgatg tacatataaa cgcttttgtt gtatggctcc tccatgttac     6900

tgtatatatc tgccagcact tcccagttac actcctgtga gtcagcttat ttttacccta     6960

acataaatag tatgttttgt agtagttatc aaatttaaga gataaagcaa tcagaatgtt     7020

tggattttct tctatcttaa tgtgaatttc ataattaatg tctatttatt cagctattca     7080

ttaaaataca ggattctttg ggaaaacatg aaaaa                                7115


<210>  1325
<211>  3203
<212>  DNA
<213>  homo sapiens

<400>  1325
acattaaccc ctgactcaca gctggaccgc cccggcccgc agcgccacgt cccgggtggg       60

gcctgccacg gcaaagcagc agtccggcct cgagcggccc ctcgggggcg gcggggtggg      120

cgccaacagc agtcaggcct gacaagcggc gacctccaag ggtgaggcct ctgcgggccc      180

ccgactcacg cgcgtccggg ctctgcaagc gcggtgggga gcaggctgct gtggtcgcgg      240

ggactgggtt gcggcgcgcc gcgtacggga cggccccaaa ctctcgacgc ccggggcaag      300

acgcccaccc cctgggcgct ctcgctgggc cagaaaggaa gacagaaaag ccgcgggctg      360

actgtggtgg cgctcgcctg cagattgaaa agaaatgctg agaaatacat aaagttttcc      420

tcttctgcct tggatattta taatgggtat cgggaagtct aaaataaatt cctgccctct      480

ttctctctct tggggtaaaa ggcacagtgt ggatacaagt ccaggatatc atgagtcaga      540

ttccaagaag tctgaagatc tatccttgtg taatgttgct gagcacagca atacaacaga      600

ggggccaaca ggaaagcagg agggagctca gagcgtggaa gagatgtttg aagaagaagc      660

tgaagaagag gtgttcctca aatttgtgat attgcatgca gaagatgaca cagatgaagc      720

cctcagagtc cagaatctgc tacaagatga ctttggtatc aaacccggaa taatctttgc      780

tgagatgcca tgtggcagac agcatttaca gaatttagat gatgctgtaa atgggtctgc      840

atggacaatc ttattactga ctgaaaactt tttaagagat acttggtgta atttccagtt      900

ctatacgtcc ctaatgaact ccgttaacag gcagcataaa tacaactctg ttatacccat      960

gcggcccctg aacaatcccc ttccccgaga aaggactccc tttgccctcc aaaccatcaa     1020

tgccttagag gaagaaagtc gtggatttcc tacacaagta gaaagaattt ttcaggagtc     1080

tgtgtataag acacaacaaa ctatatggaa agagacaaga aatatggtac aaagacaatt     1140

tattgcctga gatgaaacat ataacatgtg gctggctctt gttttgtaaa ccaaatgatt     1200

aatcttcact tgagaaagca gtttctagga aatgtttaaa taaaagagag tcttcacctt     1260

aaagaaacct atggagcaca agaaagataa atttctgcag gacagcctat aaaattgtgg     1320

tactttttga tgtttcagta aacttgacat tgtcagagtt tcaaggactt ttctttcaca     1380

attttcctag ttcatggata tgaaaaagga attctcaatc catattcctt gtattgaacc     1440

ttgaacaaaa acttgtatga cagacatttt taaaaatgtg acaacacttt tattctctga     1500

attttgatct caaaggacac agaaaaaaaa tggccccagg agatctgatc acacttcctc     1560

ctgaggcacc tctcatggat gttgcaataa gcattcgggt actatcaccc agaaatatga     1620

attgccagaa tagaacattt agcatgttaa gcgttgatgc atataaaatc agaaatagat     1680

gtgagaatgg tggaactttt taaaagaacc cagtcaaatg tattttctgc tgaaatctgc     1740

atatttggag gcatttccca ccaccgattc acagcccatt tgatagtgtg gtagttaggg     1800

acttcgtgga gtggtgttca gacgtcccct ggggcttaaa tctcttcata ttagtcatca     1860

tttgtaacta tggctttatt tgcagagctt ctaaaaggcg tataactgtg tgagtggcca     1920

gatattcact ttttaaatca aaaacctctc ttatggaagc tttaaaagtt tccgtcacac     1980

acaattctct tctcaggaag tatttctcat ttaggtcttc aaagtagcct gactgtgtgc     2040

atgtgtgtgt gtgataggtt atttataaag actttggata gaaggagatg tattttatta     2100

cctcctattc tagagcccca tgctcctaac aagccagaga ggccccaaac aggattgttt     2160

ctttcctcca cagcccttct gcccatctga gattgaggga gcatcgtcca cttgagatca     2220

gggatggggt ggagaatggg tcatgtcatg taatgagaaa agccctcttc gggatcatga     2280

gacttggttc tagtccaatt tctgccactg aggatgaatg taactgtggg caaactattt     2340

accctccttt atctgtgaaa tgaaagggtt gaattgatgg atctctaaag gcttttgtcc     2400

tctatgagga tgtgaaaaac tagggaccac aaaagggaac aagcaaaaaa gtttggattc     2460

gataaagtga tatgtaatag ttgcagaagg ctttatatat gcttataatg aaaagatatt     2520

ttttgtatat tgacagcata atttattttt aatgctgtca ttacacttaa agtcacagga     2580

aaaaaatata catgcttact caggctttct taaaaataaa tttttataga gatccttgag     2640

taaagacatt ttgcttaatt tcttttttct tattccccac ttgtatatcc cctaccagta     2700

ccgggatctg cacacatctt tttgcagtta cctcttcata gccatgaacc aaaacgttct     2760

atgaggagca tgcaagtaag tcaagcctcc tattctgtta gtacttatta gaggaggaga     2820

tggttttcat tgcatagtga cattttctta gccttaacgt tctgatagta gcttactact     2880

cacttctctt tttcagtttt cataataagt attcattttt ttgccataat gcttcctgta     2940

aagccaattt tatatactaa taaaacatga actgcccact cttcatgcct gccaaacttg     3000

gggcaattga tgctaaatgg tatttttaaa ataaatgttt ttattcttta ctcttgacta     3060

aacttgttta ttttcaactc caatgaagat tgtggaagag tgttttgaaa tgaagcatcg     3120

atttgtactt catagagcac cagacacaat gtctcaccca atttggagtt ccatattttt     3180

tttatgataa agaaaaatgt tgg                                             3203


<210>  1326
<211>  4063
<212>  DNA
<213>  homo sapiens

<400>  1326
cctcgtccca ggctgcaacg gaggcagagc caacgcctcg cgggcttcca cgtacgcact       60

ccaacgcgtg ttcccggaga agaacgcatc cgggtcacgg gagccggtgt ctcaggctcc      120

gccccttcac cccccgaaag gctaatcccc acttccgacc ctctcaggcc ttttccgctt      180

ctcttttacc tccccaggtc cgcccgtctg cgcccctcac aggaagccgg agggtcgctc      240

tgatcccgaa tctcccacag gcgtgaacct gctctgctgt gtatctttgc ggggtggcct      300

gcgctgaggc ctgccgcgcg cggtgagtcc gcgcagacct gaccctgcgt ctcgcagctc      360

ggttgaggcc gccgccgcct tctcgggatg ccgcggccgg ggtccgcgca gcgctgggcg      420

gccgtcgcgg gccgttgggg gtgcaggctg ctcgcactgc tgctactggt gcctggaccc      480

ggcggcgcct ctgagatcac cttcgagctt cctgacaacg ccaagcagtg cttctacgag      540

gacatcgctc agggcaccaa gtgcaccctg gagttccagg tgattactgg tggtcactat      600

gatgtagatt gtcgattaga agatcctgat ggtaaagtgt tatacaaaga gatgaagaaa      660

cagtatgata gttttacctt cacagcctcc aaaaatggga catacaaatt ttgcttcagc      720

aatgaatttt ctactttcac acataaaact gtatattttg attttcaagt tggagaagac      780

ccacctttgt ttcctagtga gaaccgagtc agtgctctta cccagatgga atctgcctgt      840

gtttcaattc acgaagctct gaagtctgtc atcgattatc agactcattt ccgtttaaga      900

gaagctcaag gccgaagccg agcagaggat ctaaatacaa gagtggccta ttggtcagta      960

ggagaagccc tcattcttct ggtggttagc atagggcagg tatttctttt gaaaagcttt     1020

ttctcagata aaagaaccac cacaactcgt gttggatcat aactacgttt tgagaattga     1080

tgcaccattg ccactgtaat attgctgtcc tctaattaat tttaggtact gaagaactta     1140

atattggcaa catttttaaa tccttactca tacacttgtt gggagggatg tacaatgcat     1200

attcccaaac tgtggaaagg acaccttttt ttatttgtaa aggtggaaaa actttggaac     1260

tcattttggg ctattcatgt taaatattca acaccaatga tctactctgt tcgcagttgt     1320

ttatatctac tcttcgcaca ctaaactttg gtattttgat tccttttaac catttaagac     1380

tacttttctt ataggtagtt gatattttaa aaactttaga tttaatgtct acatgtgtta     1440

gggaggaaga aaattgcctt ttaattgtta ataagaaaac caaatgtgat gaactgtagc     1500

ccaagcccta ttctgcactg ttcagtttta tggaggaaaa ataaatctac cataggaatg     1560

ttagttaata ttgatatatc atggtaaaat tgatttctca ctagcttaga aaatgtcaga     1620

cttttgtttt tggggtttat aatttaaacc agctatgcta ttttttcata aaggcatttg     1680

tagtacacag aaaacagtag tttcagtagt gtaaaagagt ttatacaggc cttaaatatc     1740

agactttgta acaggtagaa atattacaga ataatttaag acactacaat gggggcaaat     1800

gaaataggaa aatttttagt gagttacacg tactcattac attttcagtg cttttacaag     1860

gaaaaaaggt gatatgttta attttaaaat tttaattggc tagctcttgc ccttatatga     1920

ctttaatgtc tgtgagtcat tcccagctta aattaacaat tgttagtatt agtctcacac     1980

ataagtgcca tacattttat cctcatggat gtgatgcact gaaaagttag ttgctctcct     2040

tttttctttt ttttgtcgtg catattttat ttctgtagtt tctggttagc taccctaaag     2100

tgatttaaaa atttagaatg ctttgtgttt cctatttggt aatcttcatt gacttttctt     2160

tagttaatga gtattaaata gtgcatattc tgtagactat agggtttaca ttgtgttgca     2220

tcttataact tgtatagatt gagctgattg aaataagatt ttgttccaag tattatctga     2280

tagaatacaa gatgattcaa aattatatag atatttaaag cttttctgct gttttttttt     2340

tttttaattg caactgcttt tctgccgtgc ctctcttccc tacccaaaag tgatgagttc     2400

tgaacaagac aagactgtca tattgtagag actttggtat gtgataccat agaatactga     2460

ttggatagcc atcctagtca cttaccaata ctgactagaa gttaactctt aattctaagc     2520

tatcttaaaa tgcatatata tacttcttgc atggaagagc aaaacaaatt caagttgtca     2580

tgcctgataa tttcagatgc caccgtatag caaagggtga acatgttttc aaccctttaa     2640

ctttttacgg tgtttgaaga ccagctactc cttaatattt atcaatggat taagaagttt     2700

aagattttgc agatttatca atttgggttt ttgtactgaa gttgtcttgc ggctttgcaa     2760

gtgtcccttt atatttaaat ttgaaagttg taagcactga tgttaatgtg attgatcagc     2820

atgggcatat gtaaaatgtc cttttctggt tgcctctcta tgctattgtg ttcagatact     2880

tacaccataa ttaaacagta agttatagac ttgctgagtt tggcatagat agtgcactca     2940

tttaatctgt gcctctcaaa acttcagaat attagcatat taccacaaat aatttttggt     3000

gaaactattg agatattaaa atttttgaaa tcactactgt tacctgttat agaaaatagt     3060

gttggcttag tctagtctct gtgtaactgg ttacattttg atggttgtct atactcaact     3120

ggatatgtgt atgtaaatta gaaaatacat acctatccag acataaatgc taagtaacat     3180

ttttttcttc ctccaactac ataatttgta gctcatcatt tttccttaat cctttcctaa     3240

cttgttgcag cagtttgaat ttcccagata tttatgtttg aacataatgg ctcagaatac     3300

atatttgaac atcatagttg tatatatttt taaagtagaa taaataatgg aaagcaactt     3360

gatatacaag tttatactaa aatttcaact gtgtgaagat acattttaag gcattacttt     3420

gctaataatc tacacattct tttttctatt aaataaacaa atggtttgtg gttcacagct     3480

ttcatccaag cttggtgata atcaattttg aaaatacagt ggactgaaaa gcaaatttat     3540

tctttcgaag atttcattta aatctctgta ctatgcattt ttgtttcagt ttgtaaatgt     3600

gtaacattta tagttaaata ggacaaagca ggccctatga ctattgtttt caaaaaatta     3660

atatataaat aattcagagg ggtttttcat ttacttttga aaagaaattt ctttaacagg     3720

attgcaccta tcaatttctt gtagaataaa aaaaaatctt tcaacaaact gactttactt     3780

gtttctgtca ggatttaaat ctttctaaag ctccttataa acttaaagcc tagagtacag     3840

ttctgtaatg agagtgatta tttatttggt attttattaa aatatctgag ggactgtcca     3900

agaaagaagg tgaaagagaa ataccacgtc tgtactgcct aatttgtaac cttctctttg     3960

cattccttac tgaaagtttg tgtaggtgaa aagcagttaa atcatcagtt gctctaaaga     4020

ggtcttaatt tttaagtaaa ttacctttag tttgtatatt acc                       4063


<210>  1327
<211>  7492
<212>  DNA
<213>  homo sapiens

<400>  1327
ggcgctgagc gagctcggag cccgcgctgt gcgcctgcgg ccggggcgcc ccgccgagcg       60

ccggtgcccc ggctcccggg ccgccttcgc cgcgcgggaa ggattcttca aaattaacag      120

aaaccaattc gggccagctg aagagaaaaa ataaaggtgg ctcccggctg cctctgctgc      180

agttcagagc aacttcagga gcttcccagc cgagagcttc aggacgcctt tcctgtccca      240

ctggcccagt tgccacaaca aacaacagag aagacggtga ccatggggga tgtgaagctg      300

gttgcctcgt cacacatttc caaaacctcc ctcagtgtgg atccctcaag agttgactcc      360

atgcccctga cagaggcccc tgctttcatt ttgccccctc ggaacctctg catcaaagaa      420

ggagccaccg ccaagttcga agggcgggtc cggggttacc cagagcccca ggtgacatgg      480

cacagaaacg ggcaacccat caccagcggg ggccgcttcc tgctggattg cggcatccgg      540

gggactttca gccttgtgat tcatgctgtc catgaggagg acaggggaaa gtatacctgt      600

gaagccacca atggcagtgg tgctcgccag gtgacagtgg agttgacagt agaaggaagt      660

tttgcgaagc agcttggtca gcctgttgtt tccaaaacct taggggatag attttcagct      720

ccagcagtgg agacccgtcc tagcatctgg ggggagtgcc caccaaagtt tgctaccaag      780

ctgggccgag ttgtggtcaa agaaggacag atgggacgat tctcctgcaa gatcactggc      840

cggccccaac cgcaggtcac ctggctcaag ggaaatgttc cactgcagcc gagtgcccgt      900

gtgtctgtgt ctgagaagaa cggcatgcag gttctggaaa tccatggagt caaccaagat      960

gacgtgggag tgtacacgtg cctggtggtg aacgggtcgg ggaaggcctc gatgtcagct     1020

gaactttcca tccaaggttt ggacagtgcc aataggtcat ttgtgagaga aacaaaagcc     1080

accaattcag atgtcaggaa agaggtgacc aatgtaatct caaaggagtc gaagctggac     1140

agtctggagg ctgcagccaa aagcaagaac tgctccagcc cccagagagg tggctcccca     1200

ccctgggctg caaacagcca gcctcagccc ccaagggagt ccaagctgga gtcatgcaag     1260

gactcgccca gaacggcccc gcagaccccg gtccttcaga agacttccag ctccatcacc     1320

ctgcaggccg caagagttca gccggaacca agagcaccag gcctgggggt cctatcacct     1380

tctggagaag agaggaagag gccagctcct ccccgtccag ccaccttccc caccaggcag     1440

cctggcctgg ggagccaaga tgttgtgagc aaggctgcta acaggagaat ccccatggag     1500

ggccagaggg attcagcatt ccccaaattt gagagcaagc cccaaagcca ggaggtcaag     1560

gaaaatcaaa ctgtcaagtt cagatgtgaa gggcttgccg tgatggaggt ggccccctcc     1620

ttctccagtg tcctgaagga ctgcgctgtt attgagggcc aggattttgt gctgcagtgc     1680

tccgtacggg ggaccccagt gccccggatc acttggctgc tgaatgggca gcccatccag     1740

tacgctcgct ccacctgcga ggccggcgtg gctgagctcc acatccagga tgccctgccg     1800

gaggaccatg gcacctacac ctgcctagct gagaatgcct tggggcaggt gtcctgcagc     1860

gcctgggtca ccgtccatga aaagaagagt agcaggaaga gtgagtacct tctgcctgtg     1920

gctcccagca agcccactgc acccatcttc ctgcagggcc tctctgatct caaagtcatg     1980

gatggaagcc aggtcactat gactgtccaa gtgtcaggga atccaccccc tgaagtcatc     2040

tggctgcaca atgggaatga gatccaagag tcagaggact tccactttga acagagagga     2100

actcagcaca gcctttgtat ccaggaagtg ttcccggagg acacgggcac gtacacctgc     2160

gaggcctgga acagcgctgg agaggtccgc acccaggccg tgctcacggt acaagagcct     2220

cacgatggca cccagccctg gttcatcagt aagcctcgct cagtgacagc ctccctgggc     2280

cagagtgtcc tcatctcctg cgccatagct ggtgacccct ttcctaccgt gcactggctc     2340

agagatggca aagccctctg caaagacact ggccacttcg aggtgcttca gaatgaggac     2400

gtgttcaccc tggttctaaa gaaggtgcag ccctggcatg ccggccagta tgagatcctg     2460

ctcaagaacc gggttggcga atgcagttgc caggtgtcac tgatgctaca gaacagctct     2520

gccagagccc ttccacgggg gagggagcct gccagctgcg aggacctctg tggtggagga     2580

gttggtgctg atggtggtgg tagtgaccgc tatgggtccc tgaggcctgg ctggccagca     2640

agagggcagg gttggctaga ggaggaagac ggcgaggacg tgcgaggggt gctgaagagg     2700

cgcgtggaga cgaggcagca cactgaggag gcgatccgcc agcaggaggt ggagcagctg     2760

gacttccgag acctcctggg gaagaaggtg agtacaaaga ccctatcgga agacgacctg     2820

aaggagatcc cagccgagca gatggatttc cgtgccaacc tgcagcggca agtgaagcca     2880

aagactgtgt ctgaggaaga gaggaaggtg cacagccccc agcaggtcga ttttcgctct     2940

gtcctggcca agaaggggac ttccaagacc cccgtgcctg agaaggtgcc accgccaaaa     3000

cctgccaccc cggattttcg ctcagtgctg ggtggcaaga agaaattacc agcagagaat     3060

ggcagcagca gtgccgagac cctgaatgcc aaggcagtgg agagttccaa gcccctgagc     3120

aatgcacagc cttcagggcc cttgaaaccc gtgggcaacg ccaagcctgc tgagaccctg     3180

aagccaatgg gcaacgccaa gcctgccgag accctgaagc ccatgggcaa tgccaagcct     3240

gatgagaacc tgaaatccgc tagcaaagaa gaactcaaga aagacgttaa gaatgatgtg     3300

aactgcaaga gaggccatgc agggaccaca gataatgaaa agagatcaga gagccagggg     3360

acagccccag ccttcaagca gaagctgcaa gatgttcatg tggcagaggg caagaagctg     3420

ctgctccagt gccaggtgtc ttctgacccc ccagccacca tcatctggac gctgaacgga     3480

aagaccctca agaccaccaa gttcatcatc ctctcccagg aaggctcact ctgctccgtc     3540

tccatcgaga aggcactgcc tgaggacaga ggcttataca agtgtgtagc caagaatgac     3600

gctggccagg cggagtgctc ctgccaagtc accgtggatg atgctccagc cagtgagaac     3660

accaaggccc cagagatgaa atcccggagg cccaagagct ctcttcctcc cgtgctagga     3720

actgagagtg atgcgactgt gaaaaagaaa cctgccccca agacacctcc gaaggcagca     3780

atgccccctc agatcatcca gttccctgag gaccagaagg tacgcgcagg agagtcagtg     3840

gagctgtttg gcaaagtgac aggcactcag cccatcacct gtacctggat gaagttccga     3900

aagcagatcc aggaaagcga gcacatgaag gtggagaaca gcgagaatgg cagcaagctc     3960

accatcctgg ccgcgcgcca ggagcactgc ggctgctaca cactgctggt ggagaacaag     4020

ctgggcagca ggcaggccca ggtcaacctc actgtcgtgg ataagccaga ccccccagct     4080

ggcacacctt gtgcctctga cattcggagc tcctcactga ccctgtcctg gtatggctcc     4140

tcatatgatg ggggcagtgc tgtacagtcc tacagcatcg agatctggga ctcagccaac     4200

aagacgtgga aggaactagc cacatgccgc agcacctctt tcaacgtcca ggacctgctg     4260

cctgaccacg aatataagtt ccgtgtacgt gcaatcaacg tgtatggaac cagtgagcca     4320

agccaggagt ctgaactcac aacggtagga gagaaacctg aagagccgaa ggatgaagtg     4380

gaggtgtcag atgatgatga gaaggagccc gaggttgatt accggacagt gacaatcaat     4440

actgaacaaa aagtatctga cttctacgac attgaggaga gattaggatc tgggaaattt     4500

ggacaggtct ttcgacttgt agaaaagaaa actcgaaaag tctgggcagg gaagttcttc     4560

aaggcatatt cagcaaaaga gaaagagaat atccggcagg agattagcat catgaactgc     4620

ctccaccacc ctaagctggt ccagtgtgtg gatgcctttg aagaaaaggc caacatcgtc     4680

atggtcctgg agatcgtgtc aggaggggag ctgtttgagc gcatcattga cgaggacttt     4740

gagctgacgg agcgtgagtg catcaagtac atgcggcaga tctcggaggg agtggagtac     4800

atccacaagc agggcatcgt gcacctggac ctcaagccgg agaacatcat gtgtgtcaac     4860

aagacgggca ccaggatcaa gctcatcgac tttggtctgg ccaggaggct ggagaatgcg     4920

gggtctctga aggtcctctt tggcacccca gaatttgtgg ctcctgaagt gatcaactat     4980

gagcccatcg gctacgccac agacatgtgg agcatcgggg tcatctgcta catcctaaac     5040

cgcctggact gcacgcagtg ccttcagcat ccatggctaa tgaaagatac caagaacatg     5100

gaggccaaga aactctccaa ggaccggatg aagaagtaca tggcaagaag gaaatggcag     5160

aaaacgggca atgctgtgag agccattgga agactgtcct ctatggcaat gatctcaggg     5220

ctcagtggca ggaaatcctc aacagggtca ccaaccagcc cgctcaatgc agaaaaacta     5280

gaatctgaag aagatgtgtc ccaagctttc cttgaggctg ttgctgagga aaagcctcat     5340

gtaaaaccct atttctctaa gaccattcgc gatttagaag ttgtggaggg aagtgctgct     5400

agatttgact gcaagattga aggataccca gaccccgagg ttgtctggtt caaagatgac     5460

cagtcaatca gggagtcccg ccacttccag atagactacg atgaggacgg gaactgctct     5520

ttaattatta gtgatgtttg cggggatgac gatgccaagt acacctgcaa ggctgtcaac     5580

agtcttggag aagccacctg cacagcagag ctcattgtgg aaacgatgga ggaaggtgaa     5640

ggggaagggg aagaggaaga agagtgaaac aaagccagag aaaagcagtt tctaagtcat     5700

attaaaagga ctatttctct aaaactcaaa aaaaaaaaaa aaactcaaga tagtaaaagc     5760

acctagtgtg atagattatc ggttaggtca tttgtgggtt gattcttcag aaacagcagt     5820

tgatacctag cagcgttatt gatgggcatt aatctatgtt agttggcacc ttaagatact     5880

agtgcagcta gatttcattt agggaaatca ccagtaactt gactgaccaa ttgattttag     5940

agagaaagta accaaaccaa atatttatct gggcaaagtc ataaattctc cacttgaatg     6000

cgctcatgaa aaataaggcc aaaacaagag ttctgggcca cagctcagcc cagagggttc     6060

ctggggatgg gaggcctctc tctccccacc ccctgactct agagaactgg gttttctccc     6120

agtactccag caattcattt ctgaaagcag ttgagccact ttattccaaa gtacactgca     6180

gatgttcaaa ctctccattt ctctttcccc ttccacctgc cagttttgct gactctcaac     6240

ttgtcatgag tgtaagcatt aaggacatta tgcttcttcg attctgaaga caggtccctg     6300

ctcatggatg actctggctt ccttaggaaa atatttttct tccaaaatca gtaggaaatc     6360

taaacttatc ccctctttgc agatgtctag cagcttcaga catttggtta agaacccatg     6420

ggaaaaaaaa aatccttgct aatgtggttt cctttgtaaa ccaggattct tatttgtgct     6480

gttatagaat atcagctctg aacgtgtggt aaagattttt gtgtttgaat ataggagaaa     6540

tcagtttgct gaaaagttag tcttaattat ctattggcca cgatgaaaca gatttcaact     6600

gataaagagc tggagaactc catgtacttt ggaatctcct ccaagatagc cagagtttaa     6660

tacatcttca ttctcaacac tctccaaaga acttgaccta ccttatgggt tccatatttt     6720

tcttcttaaa tgtgcatcaa tcatgccttg cccccaacct ttaaatatat tcttagacct     6780

ggtaaatgca ctcagacttg cgtctttagg aatttttaac tttctttcac tacattggca     6840

cttaaatttt ttctttataa agctttttga aggtcataaa caaagaccat aattgatgat     6900

agacctaata catttcctct gtgtgtgtgt gtaacattcc aaatactttt tttttctttt     6960

ccactgtttg taaggtgcaa caatttaata tttttaaggg actttttaag agttccttaa     7020

gaaccaattt aaaattactt cagtgcaatc ctacacagta tcaacattag aattttgata     7080

ttagtcttat gttatcttcc attctatttt tatctgcttt ttgctgctag tttcaaactg     7140

ccagtatttt tccttttgct tttaaaatag ttacaatatt tttcatgata gccacagtat     7200

tgccacagtt tattataata aagggttttt atttgattta gcgcattcaa agcttttttc     7260

tatcactttt gtgttcagaa tataaccttt gtgtgcgtgt atgttgtgtg tgtgcatgtg     7320

tggcgtatat gtgtgttaca ggttaatgcc ttcttggaat tgtgttaatg ttctcttggt     7380

ttattatgcc atcagaatgg taaatgagaa cactacaact gtagtcagct cacaattttt     7440

aaataaagga taccacagtg catgctgttt gttcaaaaaa aaaaaaaaaa aa             7492


<210>  1328
<211>  3684
<212>  DNA
<213>  homo sapiens

<400>  1328
ccgcggaccc accccctcgc ttccggcatc ggctgtgggg agtaccggct gcagtcggct       60

gtgccgggag ggtaggatgg cgtctggccg atgcggtgat agcaccgaaa gcagacggcc      120

gccaggcgct ccccctaccc cccgaagttt ctccccagcg gcgggggatg ggggtaggcg      180

gttcctctgt tctttctgcg ttccccgcgg cctcttacca cagagacgcg ggcctccacc      240

gtcctagccc tcccgccctg ttctctagtg cggactagag cgtctcctcg ccatttcctg      300

tcgccctggg gccccgcggg gaaaaagggg gagtagcagg acagcggagg gaagtcgcga      360

gcttaggtgg tgtgtagacg ccggaagtgt tgggaaggag gccggaagct aggggcgggg      420

ccaggaagtg aggaggggcg ggggtttatg aggagtccaa gggagcattg gggcagactt      480

gtactcagag ccacctgagg gacttggcgg tggcgcccag cactgtcccc tcccctcgta      540

gagacacggt tgtcgtttgg gagtagggaa cactgtgttg gggtgggttg tcggcaggac      600

atctctctgg ctgctcttgg ggcgaggtgt ggaggggcag ggctgggggt ggagccgggt      660

cgccagggcg tcggtaggga agacccccgc ccctcgcccc cccaccgaac ctctacactg      720

gctggctgga cactaagatg gctgccgttg ccatgacacc caaccctgtg cagacccttc      780

aggaggaggc ggtgtgcgcc atctgcctcg attacttcac ggaccccgtg tccatcggct      840

gcgggcacaa cttctgccga gtttgtgtaa cccagttgtg gggtggggag gatgaggagg      900

acagagatga gttagatcgg gaggaggagg aggaggacgg agaggaggag gaagtggagg      960

ctgtgggggc tggcgcgggg tgggacaccc ccatgcggga tgaagactac gagggtgaca     1020

tggaggagga ggtcgaggag gaagaagagg gtgtgttctg gaccagtggc atgagcaggt     1080

ccagctggga caacatggac tatgtgtggg aggaggagga cgaggaggaa gacctggact     1140

actacttggg ggacatggag gaggaggacc tgagggggga ggatgaggag gacgaggagg     1200

aagtgctgga ggaggttgag gaagaggatc tagaccccgt caccccactg cccccgcctc     1260

cagcccctcg gaggtgcttc acatgccctc agtgccgaaa gagctttcct cggcggagct     1320

tccgccccaa cctgcagctg gccaatatgg tccaggtgat tcggcagatg cacccaaccc     1380

ctggtcgagg gagccgcgtg accgatcagg gcatctgtcc caaacaccaa gaagccctga     1440

agctcttctg cgaggtagac gaagaggcca tctgtgtggt gtgccgagaa tccaggagcc     1500

acaaacagca cagcgtggtg ccattggagg aggtggtgca ggagtacaag gccaaactgc     1560

aggggcacgt ggaaccactg aggaagcacc tggaggcagt gcagaagatg aaagccaagg     1620

aggagaggcg agtgacagaa ctgaagagcc agatgaagtc agagctggca gcggtggcct     1680

cggagtttgg gcgactgaca cggtttctgg ctgaagagca ggcagggctg gaacggcgtc     1740

tcagagagat gcatgaagcc cagctggggc gtgcgggagc cgcggctagt cgccttgcag     1800

aacaggccgc ccagctcagc cgcctgctgg cagaggccca ggagcggagc cagcaggggg     1860

gtctccggct gctccaggac atcaaggaga ctttcaatag gtgtgaagag gtacagctgc     1920

agcccccaga ggtctggtcc cctgacccgt gccaacccca tagccatgac ttcctgacag     1980

atgccatcgt gaggaaaatg agccggatgt tctgtcaggc tgcgagagtg gacctgacgc     2040

tggaccctga cacggctcac ccggccctga tgctgtcccc tgaccgccgg ggggtccgcc     2100

tggcagagcg gcggcaggag gttgctgacc atcccaagcg cttctcggcc gactgctgcg     2160

tactgggggc ccagggcttc cgctccggcc ggcactactg ggaggtagag gtgggcgggc     2220

ggcggggctg ggcggtgggt gctgcccgtg aatcaaccca tcataaggaa aaggtgggcc     2280

ctgggggttc ctccgtgggc agcggggatg ccagctcctc gcgccatcac catcgccgcc     2340

gccggctcca cctgccccag cagcccctgc tccagcggga agtgtggtgc gtgggcacca     2400

acggcaaacg ctatcaggcc cagagctcca cagaacagac gctgctgagc cccagtgaga     2460

aaccaaggcg ctttggtgtg tacctggact atgaagctgg gcgcctgggc ttctacaacg     2520

cagagactct agcccacgtg cacaccttct cggctgcctt cctgggcgag cgtgtctttc     2580

ctttcttccg ggtgctctcc aagggcaccc gcatcaagct ctgcccttga ttatcctgcc     2640

acccgcaggg gcccctctgt cagcacttgg ggggtgggtg gtggagggtg gcccgtaagt     2700

ttgagggctc aaaggctctt cccactgctt gttactgtgt tgcttcccac tcccccttga     2760

ccccaggccc ctgcttctcc ctctaggagc ctaaagaacc ctcctggcct ccagctcagc     2820

cttctctcac ctactatgtc tgtccaacag gtctgcatgg gtccctgata atgagaacag     2880

ctgcctggtc ttctctccca gtctgcctag cccagccctg ggactggaat ttgagtaggg     2940

gatgagggga aattgtaatt tcattcctta acttcctttt ccccacccct gctcttcaac     3000

ctctttatca gttctgaggc tggagggttt gggcaaggca acatccccat tccaattcca     3060

ttttctgatg cagattttag ctgagggatt tggaagccat ttggggaggc aggctgggcc     3120

aaagggtaga gctgggtaat aaatgtctat tctcctgggg aggagggatt ctaaactttc     3180

cttccgtcct caatttctac ctccatagac cggccagaat ttagcttcac ttgagagaga     3240

tctggaatgg tcgccatgat tgaaaccacg caccattaca tcatcattac attaattaca     3300

tcaacataaa ttatttcttc ccccttccct tttccagcac tcaaccaagg agcaaagctc     3360

atcccacccc acacccctcc caggtctgct cactgccagg ctcctctccc ctttgttcag     3420

tggagctggc ttttctccca gcccctttcc atgcctttca ctccatttgg caagctctga     3480

gggggagcct ggggacgggt ttgggtcccc aggaggagag ccttgggtat aatctatttt     3540

tctaggagcc tcttgccttg tcacttgcag ctttcgccct ctgctttgat ggctgaggtg     3600

aactcatgtt ctttgggaaa agggaaggcg tgctgtggaa ataaaatgtt tatttgcttc     3660

tctaaaaaaa aaaaaaaaaa aaaa                                            3684


<210>  1329
<211>  3620
<212>  DNA
<213>  homo sapiens

<400>  1329
agcgccggcg aggcgcggga ggaggagaag cagtggggag gcgcagccgc tcacctgcgg       60

ggcagggcgc ggaggaggga cccgggctgc gcgctctcgg gccgaggaac caggacgcgc      120

ccggagcctc gcacgcggcc aagctcgggg cgtcccctcc cctcggccgg gcgaactcaa      180

ggggcgcagc tctttgcttt gacagagctg gccggcggag gcgtgcagag cggcgagccg      240

gcgagccagg ctgagaaact cgagccggga acaaagaggg gtcggactga gtgtgtgtgt      300

cggctcgagc tccgggcaga ggcatttggg cccgaggccc ccgctgtgac tccccgagac      360

tccgcagtgc cctccactgc ggagtccccg cgcttgccgg caaaaacttt attcttggca      420

aacttctctt tctcttcccc tcctcctcgg cccccatctt ctgctcctcc tccttctcta      480

gcagattaaa tgagcctcga gaagaaaaac cgaagcgaaa gggaagaaaa taagaagatc      540

taaaacggac atctccagcg tgggtggctc ctttttcttt ttcttttttt cccacccttc      600

aggaagtgga cgtttcgtta tcttctgatc cttgcacctt cttttggggc aaacggggcc      660

cttctgccca gatcccctct cttttctcgg aaaacaaact actaagtcgg catccggggt      720

aactacagtg gagagggttt ccgcggagac gcgccgccgg accctcctct gcactttggg      780

gaggcgtgct ccctccagaa ccggcgttct ccgcgcgcaa atcccggcga cgcggggtcg      840

cggggtggcc gccggggcag cctcgtctag cgcgcgccgc gcagacgccc ccggagtcgc      900

cagctaccgc agccctcgcc gcccagtgcc cttcggcctc gggggcgggc gcctgcgtcg      960

gtctccgcga agcgggaaag cgcggcggcc gccgggattc gggcgccgcg gcagctgctc     1020

cggctgccgg ccggcggccc cgcgctcgcc cgccccgctt ccgcccgctg tcctgctgca     1080

cgaacccttc caactctcct ttcctccccc acccttgagt tacccctctg tctttcctgc     1140

tgttgcgcgg gtgctcccac agcggagcgg agattacaga gccgccggga tgccccaact     1200

ctccggagga ggtggcggcg gcggggggga cccggaactc tgcgccacgg acgagatgat     1260

ccccttcaag gacgagggcg atcctcagaa ggaaaagatc ttcgccgaga tcagtcatcc     1320

cgaagaggaa ggcgatttag ctgacatcaa gtcttccttg gtgaacgagt ctgaaatcat     1380

cccggccagc aacggacacg aggtggccag acaagcacaa acctctcagg agccctacca     1440

cgacaaggcc agagaacacc ccgatgacgg aaagcatcca gatggaggcc tctacaacaa     1500

gggaccctcc tactcgagtt attccgggta cataatgatg ccaaatatga ataacgaccc     1560

atacatgtca aatggatctc tttctccacc catcccgaga acatcaaata aagtgcccgt     1620

ggtgcagcca tcccatgcgg tccatcctct cacccccctc atcacttaca gtgacgagca     1680

cttttctcca ggatcacacc cgtcacacat cccatcagat gtcaactcca aacaaggcat     1740

gtccagacat cctccagctc ctgatatccc tactttttat cccttgtctc cgggtggtgt     1800

tggacagatc accccacctc ttggctggca aggtcagcct gtatatccca tcacgggtgg     1860

attcaggcaa ccctacccat cctcactgtc agtcgacact tccatgtcca ggttttccca     1920

tcatatgatt cccggtcctc ctggtcccca cacaactggc atccctcatc cagctattgt     1980

aacacctcag gtcaaacagg aacatcccca cactgacagt gacctaatgc acgtgaagcc     2040

tcagcatgaa cagagaaagg agcaggagcc aaaaagacct cacattaaga agcctctgaa     2100

tgcttttatg ttatacatga aagaaatgag agcgaatgtc gttgctgagt gtactctaaa     2160

agaaagtgca gctatcaacc agattcttgg cagaaggtgg catgccctct cccgtgaaga     2220

gcaggctaaa tattatgaat tagcacggaa agaaagacag ctacatatgc agctttatcc     2280

aggctggtct gcaagagaca attatggtaa gaaaaagaag aggaagagag agaaactaca     2340

ggaatctgca tcaggtacag gtccaagaat gacagctgcc tacatctgaa acatggtgga     2400

aaacgaagct cattcccaac gtgcaaagcc aaggcagcga ccccaggacc tcttctggag     2460

atggaagctt gttgaaaacc cagactgtct ccacggcctg cccagtcgac cccaaaggaa     2520

cactgacatc aattttaccc tgaggtcact gctagagacg ctgatccata aagacaatca     2580

ctgccaaccc ctctttcgtc tactgcaaga gccaagttcc aaaataaagc ataaaaaggt     2640

tttttaaaag gaaatgtaaa agcacatgag aatgctagca ggctgtgggg cagctgagca     2700

gcttttctcc cctcatatct gcgtgcactt cccagagcat cttgcatcca aacctgtaac     2760

ctttcggcaa ggacggtaac ttggctgcat ttgcctgtca tgcgcaactg gagccagcaa     2820

ccagcacatc catcagcacc ccagtggagg agttcatgga agagttccct ctttgtttct     2880

gcttcatttt tctttctttt cttttctcct aaagctttta tttaacagtg caaaaggatc     2940

gttttttttt gcttttttaa acttgaattt ttttaattta cactttttag ttttaatttt     3000

cttgtatatt ttgctagcta tgagctttta aataaaattg aaagttctgg aaaagtttga     3060

aataatgaca taaaaagaag ccttcttttt ctgagacagc ttgtctggta agtggcttct     3120

ctgtgaattg cctgtaacac atagtggctt ctccgccctt gtaaggtgtt cagtagagct     3180

aaataaatgt aatagccaaa cccactctgt tggtagcaat tggcagccct atttcagttt     3240

attttttctt ctgttttctt cttttctttt tttaaacagt aaaccttaac agatgcgttc     3300

agcagactgg tttgcagtga attttcattt ctttccttat cacccccttg ttgtaaaaag     3360

cccagcactt gaattgttat tactttaaat gttctgtatt tgtatctgtt tttattagcc     3420

aattagtggg attttatgcc agttgttaaa atgagcattg atgtacccat tttttaaaaa     3480

agcaaggcac agcctttgcc caaaactgtc atcctaacgt ttgtcattcc agtttgagtt     3540

aatgtgctga gcattttttt aaaagaagct ttgtaataaa acatttttaa aaattgtcat     3600

ttaaaaaaaa aaaaaaaaaa                                                 3620


<210>  1330
<211>  3625
<212>  DNA
<213>  homo sapiens

<400>  1330
ggcgggcgct cggcgactcg tccccggggc cccgcgcggg cccgggcagc aggggcgtga       60

tgtcacggca gggagggggc gcgggagccg ccgggccggc ggggaggcgg gggaggtgtt      120

ttccagcttt aaaaaggcag gaggcagagc gcggccctgc gtcagagcga gactcagagg      180

ctccgaactc gccggcggag tcgccgcgcc agatcccagc agcagggcgc gggcaccggg      240

gcgcgggcag ggctcggagc caccgcgcag gtcctagggc cgcggccggg ccccgccacg      300

cgcgcacacg cccctcgatg actttcctcc ggggcgcgcg gcgctgagcc cggggcgagg      360

gctgtcttcc cggagacccg accccggcag cgcggggcgg ccgcttctcc tgtgcctccg      420

cccgccgctc cactccccgc cgccgccgcg cggatgccaa gcaccagctt tccagtccct      480

tccaagtttc cacttggccc tgcggctgcg gtcttcggga gaggagaaac tttggggccc      540

gcgccgcgcg ccggcggcac catgaagtca gcggaggaag cccgaccctg cccgccctgg      600

actggcagct gccgtcccac tcaggcccgt atgagcttcg gattgaggtg cagcccaagt      660

cccaccaccg agcccactac gagacggagg gcagccgggg ggccgtgaag gcgtcggccg      720

gaggacaccc catcgtgcag ctgcatggct acttggagaa tgagccgctg atgctgcagc      780

ttttcattgg gacggcggac gaccgcctgc tgcgcccgca cgccttctac caggtgcacc      840

gcatcacagg gaagaccgtg tccaccacca gccacgaggc catcctctcc aacaccaaag      900

tcctggagat cccactcctg ccggagaaca gcatgcgagc cgtcattgac tgtgccggaa      960

tcctgaaact cagaaactcc gacattgaac ttcggaaagg agagacggac atcgggagga     1020

agaacacacg ggtacggctg gtgttccgcg ttcacgtccc gcaacccagc ggccgcacgc     1080

tgtccctgca ggtggcctcc aaccccatcg aatgctccca gcgctcagct caggagctgc     1140

ctctggtgga gaagcagagc acggacagct atccggtcgt gggcgggaag aagatggtcc     1200

tgtctggcca caacttcctg caggactcca aggtcatttt cgtggagaaa gccccagatg     1260

gccaccatgt ctgggagatg gaagcgaaaa ctgaccggga cctgtgcaag ccgaattctc     1320

tggtggttga gatcccgcca tttcggaatc agaggataac cagccccgtt cacgtcagtt     1380

tctacgtctg caacgggaag agaaagcgaa gccagtacca gcgtttcacc taccttcccg     1440

ccaacgttcc aattataaaa acagaaccca ctgatgatta tgagcctgct ccaacctgtg     1500

gaccggtgag ccaggggtta agtcctctcc caagaccata ctacagccag cagctcgcga     1560

tgccacccga ccccagctcc tgcctcgtgg ccggcttccc gccctgtccg cagagaagca     1620

ccctgatgcc agcggcccct ggcgtgagcc ccaagctcca cgacctttct cccgctgcct     1680

acaccaaggg cgttgccagc ccgggccact gtcacctcgg actcccgcag ccggccggag     1740

aggcccccgc cgtccaggac gtgcccaggc cagtggccac gcaccccggc tcgcccgggc     1800

agccaccccc ggccctgctg ccacagcagt aaatgaaata atacgaaatg acctctccag     1860

cacgagcacc cactcctagt tgccacattg gagcactcag ttcagcaggg gtatgctgac     1920

ttcagcagac aaagactttt gaataaataa actgaactca cacctggtac cactcagaac     1980

ctccaactga ctgaatgcca ggagctgaac attaatatgt gcaaagattg gctctccaac     2040

aagaaggaaa gcagggagga agggagacca ctgtgtcacc tggaggagaa gtcatctcat     2100

gacaacagaa gggaggtggc cgggctgagc acgggagacc caccgtgcag gggcctttca     2160

tgggaacggc ccacacgcag tttgacccca cgcccagccc ttctggcacc cctggggttc     2220

aatactggaa gtgccttatt taaccagacc atcagggcat catagaattg agcattgaat     2280

ttgctactgt aggagtattt ttaggagcag aaactgcaaa cacatttcat tgtgaggttt     2340

taccctctgt atgaatgaag agaacgctgg aaggctgcga gaggactcta gtatgagtct     2400

ccaacatttg gaacgtttcc tgggctgtca cgtacactcc tgctgcctta cacagtgcat     2460

tttagaatct tccagtctgt catctcagct cttttgtaac atgcttccct tgtctgcgcg     2520

gttgaaaccg taggcttgtt catagtcgca tgctcgcatc tttgttttta atctggcttc     2580

gaacatagca caagtaactt gaatagcaca tcaataggtt actggacaaa agcagaaaaa     2640

cctgttacag gatagcctgc atttgcatgt gtgtacatat ctaggcatct atttatgtat     2700

aaataataac agagccgacg tgtcctcgcc caggagggct tccctgtcag caataaccgg     2760

catccgtttt ggaacctgcg tctggggctc cagtcgctgc tcttgctggc gtccatcgcc     2820

gcctcggacg gccgtgcatt ttctcgtctc acgcagttcg aggaggaccc tagaaagcca     2880

ggagctgtga ttgacagtag ctgtaggtta ccagacggca acattagaaa gtgattgtaa     2940

ataacatgca acctaagtgt aatatatttg ttcagttata agatgattgt ttcacagaag     3000

ccttaccact ctctgcttca tctaagaaaa ccaataccaa aaacgccact ttaatgctca     3060

gccctgcgtt gtgtgttttc agatgagtta ctgttaacag gtaggtttgt gtaggccttg     3120

ctgggcactc tgtacaatta gttgcttatt acgtatgatt actcacagcg atctattgtt     3180

ccatataacc aaaaagcatg gtttattcat tgaaacacgg ttgacctgaa ctcgtgcctt     3240

aggaattaat gcccccttat ggaacctgcc tgaattgcac ctgcgggtgg aggctccggc     3300

tgtgaagtca ctgaacagaa cgtcgctgat ggagaaaggg ctcccgcaga aggaacggcc     3360

tgtaccgtgc gctccggcac aatcgcgtct cttgtgtctc actcacggaa agaaacaacc     3420

tgaaggccat cccgtcggtc tgcacgtaac cgtgaagacg tgtggccgcg tcccacctgc     3480

ggctgggtac cctgcacccg gcactgtagg agtcacgtgc agcctttctc aggggactgt     3540

cattgaaaag gaaacgtttg atgtctgtgt cagctgtctt tgtagttagg aaatagatcc     3600

aataaagccg tatttttttg ctgga                                           3625


<210>  1331
<211>  797
<212>  DNA
<213>  homo sapiens

<400>  1331
ggtcaaaatg gctggcaagc aggccatttc agcatcaggc aagtggctgg atggtattcg       60

aaaatggtat tacaatactg caggattcaa taaactgggg ttaatgagag atgatacaat      120

atatgaggat gaagacataa aagaagccat aagaaggctt cctgagaacc tttataatga      180

caggatgtgt cacattaaga gtgcattgga cctgaccatg aagcatcaga tcttgcctaa      240

agagcagtgg accaaatatg aagaggaaaa tttctacctt gaactgtatg tgcaagaggt      300

tattcgggaa agaaaagaaa gagaagaatg ggcaaagaag taatcatgta gttgaagtct      360

gtggatgcag ctgttatgaa gatggttaaa cttgaaacaa acaattttaa gaattatttg      420

gtctgcagat gttttacttt aaataaatgt ctattgtaat ggctggagtt attccaaacc      480

ttatactgaa taactactga atccatttac tgttaaattt ttttccaaat tttcaagatg      540

tttttagtag tgtttaacta cttcctggag ctcagaggcc actttatcag ttttcctcac      600

tggttggata gcccatcagt ttatgtaagg atgtaacttc catgagttat agccttatgg      660

aagctactaa ataaaaaagg gggtatgcac cccctagttt gccaggattg aaaaacagcc      720

tcttcactgc tatccaaata gatttgattt tgcatcctat catttaaaaa gaaattctgt      780

atgcactcca acatagg                                                     797


<210>  1332
<211>  2077
<212>  DNA
<213>  homo sapiens

<400>  1332
gggtctgcgg gaagcccgag ccggggcggg cccgagtcaa aggcaagtga aggtggaagc       60

ggccgcggcg gcagcagacc ccagagtcag aaggagtgag aaccctgacc cctaatccca      120

ctgcatccag ccaataggag cccagccacc atggcggagc tgcaggaggt gcagatcaca      180

gaggagaagc cactgttgcc aggacagacg cctgaggcgg ccaagactca ctctgtggag      240

acaccatacg gctctgtcac tttcactgtc tatggcaccc ccaaacccaa acgcccagcg      300

atccttacct accacgatgt gggactcaac tataaatctt gcttccagcc actgtttcag      360

ttcgaggaca tgcaggaaat cattcagaac tttgtgcggg ttcatgtgga tgcccctgga      420

atggaagagg gagcccctgt gttccctttg ggatatcagt acccatctct ggaccagctt      480

gcagacatga tcccttgcgt cctgcagtac ctaaatttct ctacaataat tggagttggt      540

gttggagctg gagcctacat cctggcgaga tatgctctta accacccgga cactgttgaa      600

ggtcttgtcc tcatcaacat tgatcccaat gccaagggtt ggatggattg ggcagcccac      660

aagctaacag gcctcacctc ttccattccg gagatgatcc ttggacatct tttcagccag      720

gaagagctct ctggaaattc tgagttgata caaaagtaca gaaatatcat tacacatgca      780

cccaacctgg ataacattga attgtactgg aacagctaca acaaccgccg agacctgaac      840

tttgagcgtg gaggtgatat caccctcagg tgtcctgtga tgctggtggt aggagaccaa      900

gcacctcatg aagatgcagt ggtggaatgt aactcaaaac tggaccccac ccagacctcg      960

ttcctcaaga tggctgactc cggaggtcag ccccagctga ctcagccagg caagctgacc     1020

gaggccttca agtacttcct gcaaggcatg ggctacatgg cctcatcctg catgactcgc     1080

ctgtcccggt ctcgtacagc ctctctgacc agtgcagcat ccgttgatgg caaccggtcc     1140

cgctctcgca ccctgtccca gagcagcgag tctggaactc tttcttcggg gcccccgggg     1200

cacaccatgg aggtctcctg ttgaatggcc cttgttgccc tagagtggga cccagccctc     1260

acctccccca gagctaacct gggaggtgct gaaggggcat tgggccaccg taagcaaggg     1320

aaaaagggca gatcatgcgg ggagatgacc ttgatctttg attgctaccc taaccttgac     1380

ctttaacccg tgattccccc cagctcctgg aagagatgtc ctaatatctc ttagggaccc     1440

agacccctaa attctcctcc tcccccattt tgatgttaag gtggagaggg catatgcatc     1500

ctctgtcctg atctaggtgt ctatagctga ggggtaagag gttgttgtag ttgtcctggt     1560

gcctccatca gactctccct acttgtccca tatttgcaag gggaggggat ttggggctgg     1620

ggctccattc accaaagctg aggtggcttc tcattaaccc tttaggactc tgaagggtat     1680

ggacctacgt gaatgtgtgt cagggggaga cttgctggtg ggttagtggt cctcaggatg     1740

tgatagaaac atccagtgta aaaaggaagt tggaatggga gttggcgggc agtgaacgag     1800

tgtggggaag gattggtgct ggggcaacag gaaggggcct ggggccgttt ggctgcacta     1860

actttggtag ctcagtgtgc atctagagtg ggactgggga gggagctaag cttgggctgg     1920

gctgcttggg gcttggcata gggtggaaag ggctaccctg gggctctgac cacactgtag     1980

tatgtgtgga gggtgccctc ccgtctccca caacttctgc tataacaata aactgtagag     2040

gaatctgagt accgttaaaa aaaaaaaaaa aaaaaaa                              2077


<210>  1333
<211>  3136
<212>  DNA
<213>  homo sapiens

<400>  1333
ggagagcgcg ccacagaacg acttttacgc aggcgcagaa gcctgtttcc cctcacccgc       60

ggcttccacc ctgcgcaggc gcaaaaagcc gcgctggcaa cctccgcagc ggtcgcgcgc      120

acccttcacc cctcttgctg cttttgtctg gcacaacctt ctcaggccct ccgcgaggcc      180

ggcccttttt ttctttcact ttccccaccc ggagagccag gtgccgagaa ctaggacctc      240

gtccccttct ctatcccttc ccctgatcca tctcgtctct gttctccttc ccttttccgt      300

tcccgaagcc ggaaggagcc gaggtaccca cggaaaaagt cgaagctgtc cccggagagt      360

gaggccttca cgaagcggtg gcggaaggag ccgaagttct ctgatcggag gcgtgagcaa      420

gtggcatctc cggaaagagc cgaaacacgg actcgagctt aatcccagga ggggcccgag      480

ggcgagatcc ggaaatctcc ggaaagagcc gaaggccggg acggttagga ttgtcggaag      540

tggccgattg cttggacagg gccggcggag aagatcggag caagtccgtg gaagaagcca      600

aagactggga cggattgaat tgttggaaga acccgaactc gcagagggga ctgggcgcag      660

tggcacacga ggacacacgg aaacctccga acgttgagga gataatctcg gaaaagttac      720

ggaaacctgg gaagtcggcg aaaccctacg ttcgggtgtt ttcggaagca gccgaagcgg      780

ccgcctgctt cgccttcgtc cagtatccgg agatagccga ggcgcttcgg agccaggctc      840

ggggggaggg gcaagctcgc gggcgggcgg gcgggtgagg gggcggagcc cgggcggggc      900

ggggagggct gccggaggct tgattaggta ggaggtggcg aagcgccggc ggcggccgga      960

agtagccgaa gccagcggcg gaagtagccg aagcggctgg agcgggcggc aaggcgaggc     1020

gaaagctgca cagggcccta cgcggccgcc tcagcatgtc ggacttcgac gagttcgagc     1080

ggcagctcaa cgagaataaa caagagcggg acaaggagaa ccggcatcgg aagcgcagcc     1140

acagccgctc tcggagccgg gaccgcaaac gccggagccg gagccgcgac cggcgcaacc     1200

gggaccagcg gagcgcctcc cgggacaggc gacgacgcag caaacctttg accagaggcg     1260

ctaaagagga gcacggtgga ctgattcgtt ccccccgcca cgagaagaag aagaaggtcc     1320

gtaaatactg ggacgtgcca cccccaggct ttgagcacat caccccaatg cagtacaagg     1380

ccatgcaagc tgcgggtcag attccagcca ctgctcttct ccccaccatg acccctgacg     1440

gtctggctgt gaccccaacg ccggtgcccg tggtcgggag ccagatgacc agacaagccc     1500

ggcgcctcta cgtgggcaac atcccctttg gcatcactga ggaggccatg atggatttct     1560

tcaacgccca gatgcgcctg ggggggctga cccaggcccc tggcaaccca gtgttggctg     1620

tgcagattaa ccaggacaag aattttgcct ttttggagtt ccgctcagtg gacgagacta     1680

cccaggctat ggcctttgat ggcatcatct tccagggcca gtcactaaag atccgcaggc     1740

ctcacgacta ccagccgctt cctggcatgt cagagaaccc ctccgtctat gtgcctgggg     1800

ttgtgtccac tgtggtcccc gactctgccc acaagctgtt catcgggggc ttacccaact     1860

acctgaacga tgaccaggtc aaagagctgc tgacatcctt tgggcccctc aaggccttca     1920

acctggtcaa ggacagtgcc acggggctct ccaagggcta cgccttctgt gagtacgtgg     1980

acatcaacgt cacggatcag gccattgcgg ggctgaacgg catgcagctg ggggataaga     2040

agctgctggt ccagagggcg agtgtgggag ccaagaatgc cacgctgagc accatcaatc     2100

agacgcctgt gaccctgcaa gtgccgggct tgatgagctc ccaggtgcag atgggcggcc     2160

acccgactga ggtcctgtgc ctcatgaaca tggtgctgcc tgaggagctg ctggacgacg     2220

aggagtatga ggagatcgtg gaggatgtgc gggacgagtg cagcaagtac gggcttgtca     2280

agtccatcga gatcccccgg cctgtggacg gcgtcgaggt gcccggctgc ggaaagatct     2340

ttgtggagtt cacctctgtg tttgactgcc agaaagccat gcagggcctg acgggccgca     2400

agttcgccaa cagagtggtt gtcacaaaat actgtgaccc cgactcttat caccgccggg     2460

acttctggta gaggcggctg ggggagggtg ggggcagggc tggctggggg cttctcccca     2520

ctcccgcccc ccccttatcc ccctctgaag acgatgggca gaggagtgac agccgcagac     2580

acacgacagc cggcagcaac tggaatggca gcaattaagg gtggggggcg ggggttgggg     2640

ggttgggggg ttagggcagg gaggggactg gggaagtgcg cacacagccc acacagacaa     2700

cacgcaccca cacagacaca gagggaaggg gttgggatgg ggacagggtg cacagcaggg     2760

cggggtagga ccccagcccc tcccaaaaca gcctctcctt ctcccataga cccctttctt     2820

ctccccttcc ccacggtagg aacatagcgt gtttatattt tatggccaaa ctattttgaa     2880

ttttgttgtc cggccctcag tgccctgccc tctcccttac caggaccaca gctctgttcc     2940

ttcggcctct ggtcctctct ggtcccctcc tgggtttctt acgtagttga tttttcctct     3000

ttagtctccc ccgacctgcg cccagccccg tggcccctgc ccctctccta ctctctgtgg     3060

cagtttcata tttgctaaga cgaatttgct cattaaacat tttgttgtat tttactttaa     3120

aaaaaaaaaa aaaaaa                                                     3136


<210>  1334
<211>  4082
<212>  DNA
<213>  homo sapiens

<400>  1334
gcgcgcgccg gcctgggcag gcgagcgggc gcgctcccgc cccctctccc ctccccgcgc       60

gcccgagcgc gcctccgccc ttgcccgccc cctgacgctg cctcagctcc tcagtgcaca      120

gtgctgcctc gtctgagggg acaggaggat caccctcttc gtcgcttcgg ccagtgtgtc      180

gggctgggcc ctgacaagcc acctgaggag aggctcggag ccgggcccgg accccggcga      240

ttgccgcccg cttctctcta gtctcacgag gggtttcccg cctcgcaccc ccacctctgg      300

acttgccttt ccttctcttc tccgcgtgtg gagggagcca gcgcttaggc cggagcgagc      360

ctgggggccg cccgccgtga agacatcgcg gggaccgatt caccatggag ggcgccggcg      420

gcgcgaacga caagaaaaag ataagttctg aacgtcgaaa agaaaagtct cgagatgcag      480

ccagatctcg gcgaagtaaa gaatctgaag ttttttatga gcttgctcat cagttgccac      540

ttccacataa tgtgagttcg catcttgata aggcctctgt gatgaggctt accatcagct      600

atttgcgtgt gaggaaactt ctggatgctg gtgatttgga tattgaagat gacatgaaag      660

cacagatgaa ttgcttttat ttgaaagcct tggatggttt tgttatggtt ctcacagatg      720

atggtgacat gatttacatt tctgataatg tgaacaaata catgggatta actcagtttg      780

aactaactgg acacagtgtg tttgatttta ctcatccatg tgaccatgag gaaatgagag      840

aaatgcttac acacagaaat ggccttgtga aaaagggtaa agaacaaaac acacagcgaa      900

gcttttttct cagaatgaag tgtaccctaa ctagccgagg aagaactatg aacataaagt      960

ctgcaacatg gaaggtattg cactgcacag gccacattca cgtatatgat accaacagta     1020

accaacctca gtgtgggtat aagaaaccac ctatgacctg cttggtgctg atttgtgaac     1080

ccattcctca cccatcaaat attgaaattc ctttagatag caagactttc ctcagtcgac     1140

acagcctgga tatgaaattt tcttattgtg atgaaagaat taccgaattg atgggatatg     1200

agccagaaga acttttaggc cgctcaattt atgaatatta tcatgctttg gactctgatc     1260

atctgaccaa aactcatcat gatatgttta ctaaaggaca agtcaccaca ggacagtaca     1320

ggatgcttgc caaaagaggt ggatatgtct gggttgaaac tcaagcaact gtcatatata     1380

acaccaagaa ttctcaacca cagtgcattg tatgtgtgaa ttacgttgtg agtggtatta     1440

ttcagcacga cttgattttc tcccttcaac aaacagaatg tgtccttaaa ccggttgaat     1500

cttcagatat gaaaatgact cagctattca ccaaagttga atcagaagat acaagtagcc     1560

tctttgacaa acttaagaag gaacctgatg ctttaacttt gctggcccca gccgctggag     1620

acacaatcat atctttagat tttggcagca acgacacaga aactgatgac cagcaacttg     1680

aggaagtacc attatataat gatgtaatgc tcccctcacc caacgaaaaa ttacagaata     1740

taaatttggc aatgtctcca ttacccaccg ctgaaacgcc aaagccactt cgaagtagtg     1800

ctgaccctgc actcaatcaa gaagttgcat taaaattaga accaaatcca gagtcactgg     1860

aactttcttt taccatgccc cagattcagg atcagacacc tagtccttcc gatggaagca     1920

ctagacaaag ttcacctgag cctaatagtc ccagtgaata ttgtttttat gtggatagtg     1980

atatggtcaa tgaattcaag ttggaattgg tagaaaaact ttttgctgaa gacacagaag     2040

caaagaaccc attttctact caggacacag atttagactt ggagatgtta gctccctata     2100

tcccaatgga tgatgacttc cagttacgtt ccttcgatca gttgtcacca ttagaaagca     2160

gttccgcaag ccctgaaagc gcaagtcctc aaagcacagt tacagtattc cagcagactc     2220

aaatacaaga acctactgct aatgccacca ctaccactgc caccactgat gaattaaaaa     2280

cagtgacaaa agaccgtatg gaagacatta aaatattgat tgcatctcca tctcctaccc     2340

acatacataa agaaactact agtgccacat catcaccata tagagatact caaagtcgga     2400

cagcctcacc aaacagagca ggaaaaggag tcatagaaca gacagaaaaa tctcatccaa     2460

gaagccctaa cgtgttatct gtcgctttga gtcaaagaac tacagttcct gaggaagaac     2520

taaatccaaa gatactagct ttgcagaatg ctcagagaaa gcgaaaaatg gaacatgatg     2580

gttcactttt tcaagcagta ggaattggaa cattattaca gcagccagac gatcatgcag     2640

ctactacatc actttcttgg aaacgtgtaa aaggatgcaa atctagtgaa cagaatggaa     2700

tggagcaaaa gacaattatt ttaataccct ctgatttagc atgtagactg ctggggcaat     2760

caatggatga aagtggatta ccacagctga ccagttatga ttgtgaagtt aatgctccta     2820

tacaaggcag cagaaaccta ctgcagggtg aagaattact cagagctttg gatcaagtta     2880

actgagcttt ttcttaattt cattcctttt tttggacact ggtggctcat tacctaaagc     2940

agtctattta tattttctac atctaatttt agaagcctgg ctacaatact gcacaaactt     3000

ggttagttca attttgatcc cctttctact taatttacat taatgctctt ttttagtatg     3060

ttctttaatg ctggatcaca gacagctcat tttctcagtt ttttggtatt taaaccattg     3120

cattgcagta gcatcatttt aaaaaatgca cctttttatt tatttatttt tggctaggga     3180

gtttatccct ttttcgaatt atttttaaga agatgccaat ataatttttg taagaaggca     3240

gtaacctttc atcatgatca taggcagttg aaaaattttt acaccttttt tttcacattt     3300

tacataaata ataatgcttt gccagcagta cgtggtagcc acaattgcac aatatatttt     3360

cttaaaaaat accagcagtt actcatggaa tatattctgc gtttataaaa ctagttttta     3420

agaagaaatt ttttttggcc tatgaaattg ttaaacctgg aacatgacat tgttaatcat     3480

ataataatga ttcttaaatg ctgtatggtt tattatttaa atgggtaaag ccatttacat     3540

aatatagaaa gatatgcata tatctagaag gtatgtggca tttatttgga taaaattctc     3600

aattcagaga aatcatctga tgtttctata gtcactttgc cagctcaaaa gaaaacaata     3660

ccctatgtag ttgtggaagt ttatgctaat attgtgtaac tgatattaaa cctaaatgtt     3720

ctgcctaccc tgttggtata aagatatttt gagcagactg taaacaagaa aaaaaaaatc     3780

atgcattctt agcaaaattg cctagtatgt taatttgctc aaaatacaat gtttgatttt     3840

atgcactttg tcgctattaa catccttttt ttcatgtaga tttcaataat tgagtaattt     3900

tagaagcatt attttaggaa tatatagttg tcacagtaaa tatcttgttt tttctatgta     3960

cattgtacaa atttttcatt ccttttgctc tttgtggttg gatctaacac taactgtatt     4020

gttttgttac atcaaataaa catcttctgt ggaccaggca aaaaaaaaaa aaaaaaaaaa     4080

aa                                                                    4082


<210>  1335
<211>  3955
<212>  DNA
<213>  homo sapiens

<400>  1335
gcgcgcgccg gcctgggcag gcgagcgggc gcgctcccgc cccctctccc ctccccgcgc       60

gcccgagcgc gcctccgccc ttgcccgccc cctgacgctg cctcagctcc tcagtgcaca      120

gtgctgcctc gtctgagggg acaggaggat caccctcttc gtcgcttcgg ccagtgtgtc      180

gggctgggcc ctgacaagcc acctgaggag aggctcggag ccgggcccgg accccggcga      240

ttgccgcccg cttctctcta gtctcacgag gggtttcccg cctcgcaccc ccacctctgg      300

acttgccttt ccttctcttc tccgcgtgtg gagggagcca gcgcttaggc cggagcgagc      360

ctgggggccg cccgccgtga agacatcgcg gggaccgatt caccatggag ggcgccggcg      420

gcgcgaacga caagaaaaag ataagttctg aacgtcgaaa agaaaagtct cgagatgcag      480

ccagatctcg gcgaagtaaa gaatctgaag ttttttatga gcttgctcat cagttgccac      540

ttccacataa tgtgagttcg catcttgata aggcctctgt gatgaggctt accatcagct      600

atttgcgtgt gaggaaactt ctggatgctg gtgatttgga tattgaagat gacatgaaag      660

cacagatgaa ttgcttttat ttgaaagcct tggatggttt tgttatggtt ctcacagatg      720

atggtgacat gatttacatt tctgataatg tgaacaaata catgggatta actcagtttg      780

aactaactgg acacagtgtg tttgatttta ctcatccatg tgaccatgag gaaatgagag      840

aaatgcttac acacagaaat ggccttgtga aaaagggtaa agaacaaaac acacagcgaa      900

gcttttttct cagaatgaag tgtaccctaa ctagccgagg aagaactatg aacataaagt      960

ctgcaacatg gaaggtattg cactgcacag gccacattca cgtatatgat accaacagta     1020

accaacctca gtgtgggtat aagaaaccac ctatgacctg cttggtgctg atttgtgaac     1080

ccattcctca cccatcaaat attgaaattc ctttagatag caagactttc ctcagtcgac     1140

acagcctgga tatgaaattt tcttattgtg atgaaagaat taccgaattg atgggatatg     1200

agccagaaga acttttaggc cgctcaattt atgaatatta tcatgctttg gactctgatc     1260

atctgaccaa aactcatcat gatatgttta ctaaaggaca agtcaccaca ggacagtaca     1320

ggatgcttgc caaaagaggt ggatatgtct gggttgaaac tcaagcaact gtcatatata     1380

acaccaagaa ttctcaacca cagtgcattg tatgtgtgaa ttacgttgtg agtggtatta     1440

ttcagcacga cttgattttc tcccttcaac aaacagaatg tgtccttaaa ccggttgaat     1500

cttcagatat gaaaatgact cagctattca ccaaagttga atcagaagat acaagtagcc     1560

tctttgacaa acttaagaag gaacctgatg ctttaacttt gctggcccca gccgctggag     1620

acacaatcat atctttagat tttggcagca acgacacaga aactgatgac cagcaacttg     1680

aggaagtacc attatataat gatgtaatgc tcccctcacc caacgaaaaa ttacagaata     1740

taaatttggc aatgtctcca ttacccaccg ctgaaacgcc aaagccactt cgaagtagtg     1800

ctgaccctgc actcaatcaa gaagttgcat taaaattaga accaaatcca gagtcactgg     1860

aactttcttt taccatgccc cagattcagg atcagacacc tagtccttcc gatggaagca     1920

ctagacaaag ttcacctgag cctaatagtc ccagtgaata ttgtttttat gtggatagtg     1980

atatggtcaa tgaattcaag ttggaattgg tagaaaaact ttttgctgaa gacacagaag     2040

caaagaaccc attttctact caggacacag atttagactt ggagatgtta gctccctata     2100

tcccaatgga tgatgacttc cagttacgtt ccttcgatca gttgtcacca ttagaaagca     2160

gttccgcaag ccctgaaagc gcaagtcctc aaagcacagt tacagtattc cagcagactc     2220

aaatacaaga acctactgct aatgccacca ctaccactgc caccactgat gaattaaaaa     2280

cagtgacaaa agaccgtatg gaagacatta aaatattgat tgcatctcca tctcctaccc     2340

acatacataa agaaactact agtgccacat catcaccata tagagatact caaagtcgga     2400

cagcctcacc aaacagagca ggaaaaggag tcatagaaca gacagaaaaa tctcatccaa     2460

gaagccctaa cgtgttatct gtcgctttga gtcaaagaac tacagttcct gaggaagaac     2520

taaatccaaa gatactagct ttgcagaatg ctcagagaaa gcgaaaaatg gaacatgatg     2580

gttcactttt tcaagcagta ggaattattt agcatgtaga ctgctggggc aatcaatgga     2640

tgaaagtgga ttaccacagc tgaccagtta tgattgtgaa gttaatgctc ctatacaagg     2700

cagcagaaac ctactgcagg gtgaagaatt actcagagct ttggatcaag ttaactgagc     2760

tttttcttaa tttcattcct ttttttggac actggtggct cattacctaa agcagtctat     2820

ttatattttc tacatctaat tttagaagcc tggctacaat actgcacaaa cttggttagt     2880

tcaattttga tcccctttct acttaattta cattaatgct cttttttagt atgttcttta     2940

atgctggatc acagacagct cattttctca gttttttggt atttaaacca ttgcattgca     3000

gtagcatcat tttaaaaaat gcaccttttt atttatttat ttttggctag ggagtttatc     3060

cctttttcga attattttta agaagatgcc aatataattt ttgtaagaag gcagtaacct     3120

ttcatcatga tcataggcag ttgaaaaatt tttacacctt ttttttcaca ttttacataa     3180

ataataatgc tttgccagca gtacgtggta gccacaattg cacaatatat tttcttaaaa     3240

aataccagca gttactcatg gaatatattc tgcgtttata aaactagttt ttaagaagaa     3300

attttttttg gcctatgaaa ttgttaaacc tggaacatga cattgttaat catataataa     3360

tgattcttaa atgctgtatg gtttattatt taaatgggta aagccattta cataatatag     3420

aaagatatgc atatatctag aaggtatgtg gcatttattt ggataaaatt ctcaattcag     3480

agaaatcatc tgatgtttct atagtcactt tgccagctca aaagaaaaca ataccctatg     3540

tagttgtgga agtttatgct aatattgtgt aactgatatt aaacctaaat gttctgccta     3600

ccctgttggt ataaagatat tttgagcaga ctgtaaacaa gaaaaaaaaa atcatgcatt     3660

cttagcaaaa ttgcctagta tgttaatttg ctcaaaatac aatgtttgat tttatgcact     3720

ttgtcgctat taacatcctt tttttcatgt agatttcaat aattgagtaa ttttagaagc     3780

attattttag gaatatatag ttgtcacagt aaatatcttg ttttttctat gtacattgta     3840

caaatttttc attccttttg ctctttgtgg ttggatctaa cactaactgt attgttttgt     3900

tacatcaaat aaacatcttc tgtggaccag gcaaaaaaaa aaaaaaaaaa aaaaa          3955


<210>  1336
<211>  3955
<212>  DNA
<213>  homo sapiens

<400>  1336
gcgcgcgccg gcctgggcag gcgagcgggc gcgctcccgc cccctctccc ctccccgcgc       60

gcccgagcgc gcctccgccc ttgcccgccc cctgacgctg cctcagctcc tcagtgcaca      120

gtgctgcctc gtctgagggg acaggaggat caccctcttc gtcgcttcgg ccagtgtgtc      180

gggctgggcc ctgacaagcc acctgaggag aggctcggag ccgggcccgg accccggcga      240

ttgccgcccg cttctctcta gtctcacgag gggtttcccg cctcgcaccc ccacctctgg      300

acttgccttt ccttctcttc tccgcgtgtg gagggagcca gcgcttaggc cggagcgagc      360

ctgggggccg cccgccgtga agacatcgcg gggaccgatt caccatggag ggcgccggcg      420

gcgcgaacga caagaaaaag ataagttctg aacgtcgaaa agaaaagtct cgagatgcag      480

ccagatctcg gcgaagtaaa gaatctgaag ttttttatga gcttgctcat cagttgccac      540

ttccacataa tgtgagttcg catcttgata aggcctctgt gatgaggctt accatcagct      600

atttgcgtgt gaggaaactt ctggatgctg gtgatttgga tattgaagat gacatgaaag      660

cacagatgaa ttgcttttat ttgaaagcct tggatggttt tgttatggtt ctcacagatg      720

atggtgacat gatttacatt tctgataatg tgaacaaata catgggatta actcagtttg      780

aactaactgg acacagtgtg tttgatttta ctcatccatg tgaccatgag gaaatgagag      840

aaatgcttac acacagaaat ggccttgtga aaaagggtaa agaacaaaac acacagcgaa      900

gcttttttct cagaatgaag tgtaccctaa ctagccgagg aagaactatg aacataaagt      960

ctgcaacatg gaaggtattg cactgcacag gccacattca cgtatatgat accaacagta     1020

accaacctca gtgtgggtat aagaaaccac ctatgacctg cttggtgctg atttgtgaac     1080

ccattcctca cccatcaaat attgaaattc ctttagatag caagactttc ctcagtcgac     1140

acagcctgga tatgaaattt tcttattgtg atgaaagaat taccgaattg atgggatatg     1200

agccagaaga acttttaggc cgctcaattt atgaatatta tcatgctttg gactctgatc     1260

atctgaccaa aactcatcat gatatgttta ctaaaggaca agtcaccaca ggacagtaca     1320

ggatgcttgc caaaagaggt ggatatgtct gggttgaaac tcaagcaact gtcatatata     1380

acaccaagaa ttctcaacca cagtgcattg tatgtgtgaa ttacgttgtg agtggtatta     1440

ttcagcacga cttgattttc tcccttcaac aaacagaatg tgtccttaaa ccggttgaat     1500

cttcagatat gaaaatgact cagctattca ccaaagttga atcagaagat acaagtagcc     1560

tctttgacaa acttaagaag gaacctgatg ctttaacttt gctggcccca gccgctggag     1620

acacaatcat atctttagat tttggcagca acgacacaga aactgatgac cagcaacttg     1680

aggaagtacc attatataat gatgtaatgc tcccctcacc caacgaaaaa ttacagaata     1740

taaatttggc aatgtctcca ttacccaccg ctgaaacgcc aaagccactt cgaagtagtg     1800

ctgaccctgc actcaatcaa gaagttgcat taaaattaga accaaatcca gagtcactgg     1860

aactttcttt taccatgccc cagattcagg atcagacacc tagtccttcc gatggaagca     1920

ctagacaaag ttcacctgag cctaatagtc ccagtgaata ttgtttttat gtggatagtg     1980

atatggtcaa tgaattcaag ttggaattgg tagaaaaact ttttgctgaa gacacagaag     2040

caaagaaccc attttctact caggacacag atttagactt ggagatgtta gctccctata     2100

tcccaatgga tgatgacttc cagttacgtt ccttcgatca gttgtcacca ttagaaagca     2160

gttccgcaag ccctgaaagc gcaagtcctc aaagcacagt tacagtattc cagcagactc     2220

aaatacaaga acctactgct aatgccacca ctaccactgc caccactgat gaattaaaaa     2280

cagtgacaaa agaccgtatg gaagacatta aaatattgat tgcatctcca tctcctaccc     2340

acatacataa agaaactact agtgccacat catcaccata tagagatact caaagtcgga     2400

cagcctcacc aaacagagca ggaaaaggag tcatagaaca gacagaaaaa tctcatccaa     2460

gaagccctaa cgtgttatct gtcgctttga gtcaaagaac tacagttcct gaggaagaac     2520

taaatccaaa gatactagct ttgcagaatg ctcagagaaa gcgaaaaatg gaacatgatg     2580

gttcactttt tcaagcagta ggaattattt agcatgtaga ctgctggggc aatcaatgga     2640

tgaaagtgga ttaccacagc tgaccagtta tgattgtgaa gttaatgctc ctatacaagg     2700

cagcagaaac ctactgcagg gtgaagaatt actcagagct ttggatcaag ttaactgagc     2760

tttttcttaa tttcattcct ttttttggac actggtggct cattacctaa agcagtctat     2820

ttatattttc tacatctaat tttagaagcc tggctacaat actgcacaaa cttggttagt     2880

tcaattttga tcccctttct acttaattta cattaatgct cttttttagt atgttcttta     2940

atgctggatc acagacagct cattttctca gttttttggt atttaaacca ttgcattgca     3000

gtagcatcat tttaaaaaat gcaccttttt atttatttat ttttggctag ggagtttatc     3060

cctttttcga attattttta agaagatgcc aatataattt ttgtaagaag gcagtaacct     3120

ttcatcatga tcataggcag ttgaaaaatt tttacacctt ttttttcaca ttttacataa     3180

ataataatgc tttgccagca gtacgtggta gccacaattg cacaatatat tttcttaaaa     3240

aataccagca gttactcatg gaatatattc tgcgtttata aaactagttt ttaagaagaa     3300

attttttttg gcctatgaaa ttgttaaacc tggaacatga cattgttaat catataataa     3360

tgattcttaa atgctgtatg gtttattatt taaatgggta aagccattta cataatatag     3420

aaagatatgc atatatctag aaggtatgtg gcatttattt ggataaaatt ctcaattcag     3480

agaaatcatc tgatgtttct atagtcactt tgccagctca aaagaaaaca ataccctatg     3540

tagttgtgga agtttatgct aatattgtgt aactgatatt aaacctaaat gttctgccta     3600

ccctgttggt ataaagatat tttgagcaga ctgtaaacaa gaaaaaaaaa atcatgcatt     3660

cttagcaaaa ttgcctagta tgttaatttg ctcaaaatac aatgtttgat tttatgcact     3720

ttgtcgctat taacatcctt tttttcatgt agatttcaat aattgagtaa ttttagaagc     3780

attattttag gaatatatag ttgtcacagt aaatatcttg ttttttctat gtacattgta     3840

caaatttttc attccttttg ctctttgtgg ttggatctaa cactaactgt attgttttgt     3900

tacatcaaat aaacatcttc tgtggaccag gcaaaaaaaa aaaaaaaaaa aaaaa          3955


<210>  1337
<211>  2374
<212>  DNA
<213>  homo sapiens

<400>  1337
ttggctgtca gtcggatccg agaacgacga ttggctttcc ttgaccgtcc ctcaagcgcc       60

tctccggaga tggtctgagg tgggagaaga gctgaagaga cctggagccg acagacgggt      120

ctgggtctgc cgcccaggat ggagtacaat ggtgtgatct tggctctttg caacctctgc      180

ctcctgggct caagccttcc tcccacctga acctcccaag tagcgggact gcagggtgaa      240

ggccatgccg cctcctggga aagttccccg aaaggagaat ctgtggctac agtgtgagtg      300

ggggtcctgc tcctttgtgt gctcaaccat ggaaaagttc tttgagcatg tcactcagca      360

cctgcagcag cacctgcatg gctctgggga ggaggaggaa gaggaagagg aggatgaccc      420

acttgaggaa gaattctcct gcttgtggca ggaatgtggc ttttgttctc tggacagttc      480

tgctgacctc atccgccatg tctacttcca ctgctaccac accaagctga aacagtgggg      540

gctgcaggcc ttgcaaagcc aggctgacct tggcccctgc atcctggact tccagagccg      600

gaacgtcatc cctgatatcc ctgaccactt cctgtgtctg tgggagcact gtgagaattc      660

cttcgacaat cctgagtggt tttatcggca tgtggaagca cacagtctgt gctgtgaata      720

cgaagcagtc ggcaaggaca acccggtggt gctgtgtggc tggaaaggct gtacctgcac      780

cttcaaggac cgcagtaaac ttcgagagca cctccgcagc catacccagg agaaagtggt      840

agcctgcccc acctgtgggg gcatgtttgc caacaatacc aagttcttag atcacatccg      900

tcgccagacc tcattggatc agcagcactt ccagtgttct cactgttcca agagatttgc      960

cacagagcgg ctattgcggg accacatgcg caaccatgtg aatcactata agtgccctct     1020

gtgtgacatg acctgcccgc tgccttcctc cctccgcaac cacatgcgct ttcgtcacag     1080

tgaggaccgg ccctttaaat gtgactgttg tgactacagc tgcaagaatc ttattgacct     1140

ccagaagcac ctggataccc acagcgagga gccagcctac aggtgtgatt ttgagaactg     1200

caccttcagt gcccgatccc tctgctctat caagtcccat taccgcaaag tacatgaagg     1260

agactctgag ccaaggtaca aatgtcatgt gtgtgacaaa tgcttcacac ggggcaacaa     1320

cctcaccgtg caccttcgca agaagcacca gttcaagtgg ccctcagggc atccccgttt     1380

tcggtacaag gaacatgaag atggctatat gcggctgcag ctggttcgct acgagagtgt     1440

agagctgaca cagcaactgc tgcggcaacc acaagaggga tcgggcctgg gaacgtcgct     1500

gaacgagagc agcctgcagg gcattattct agaaacagtg ccaggggagc caggacgtaa     1560

ggaagaggaa gaggagggca agggtagcga agggacagcc ctctcagcct ctcaggacaa     1620

ccccagttct gtcatccacg tggtgaatca gaccaatgcc caaggccagc aagagattgt     1680

ctactatgtg ctgtctgaag ccccagggga gcctccccca gcccctgagc caccttcagg     1740

gggcatcatg gaaaagcttc aaggaatagc tgaggagcca gagatccaga tggtttgaag     1800

gccgcagagc cagaccattt cttccccagg tcctgaagtt tgagccaggc aagtggcagt     1860

gcccctagtg ggcagccgtt gccaatggat gcctttagga gtggtgccga gagcagtgtg     1920

gtccactctg gcctgggttt gcatcattct gcagactcta aagacttccc ttttctgcca     1980

gactacattt tgtggggagc ctgaggactc tggattcttt gaggggatcc tggatgtgtg     2040

tgttcttgtt aaagaggctg ttatcaggct taaccataac cctcaagatc tgcttgacag     2100

tgattaaatc cttagctcac atccattccc atctttcggg ctccttaggc ccaaggatgg     2160

catgtgactg gtccctgcaa gggtcctttc tttgtcacca gccaaggcat tgataaccaa     2220

gtagccattt tcctcttaag gtttcctcta caaccccaag gactttcatg attatcctca     2280

gggacaggat tggaggcatt gagcgtgttt attaacaaat tgtttttggt aataaaataa     2340

atgcttggac tcttaaaaaa aaaaaaaaaa aaaa                                 2374


<210>  1338
<211>  2257
<212>  DNA
<213>  homo sapiens

<400>  1338
ttggctgtca gtcggatccg agaacgacga ttggctttcc ttgaccgtcc ctcaagcgcc       60

tctccggaga tggtctgagg tgggagaaga gctgaagaga cctggagccg acagacgggt      120

gaaggccatg ccgcctcctg ggaaagttcc ccgaaaggag aatctgtggc tacagtgtga      180

gtgggggtcc tgctcctttg tgtgctcaac catggaaaag ttctttgagc atgtcactca      240

gcacctgcag cagcacctgc atggctctgg ggaggaggag gaagaggaag aggaggatga      300

cccacttgag gaagaattct cctgcttgtg gcaggaatgt ggcttttgtt ctctggacag      360

ttctgctgac ctcatccgcc atgtctactt ccactgctac cacaccaagc tgaaacagtg      420

ggggctgcag gccttgcaaa gccaggctga ccttggcccc tgcatcctgg acttccagag      480

ccggaacgtc atccctgata tccctgacca cttcctgtgt ctgtgggagc actgtgagaa      540

ttccttcgac aatcctgagt ggttttatcg gcatgtggaa gcacacagtc tgtgctgtga      600

atacgaagca gtcggcaagg acaacccggt ggtgctgtgt ggctggaaag gctgtacctg      660

caccttcaag gaccgcagta aacttcgaga gcacctccgc agccataccc aggagaaagt      720

ggtagcctgc cccacctgtg ggggcatgtt tgccaacaat accaagttct tagatcacat      780

ccgtcgccag acctcattgg atcagcagca cttccagtgt tctcactgtt ccaagagatt      840

tgccacagag cggctattgc gggaccacat gcgcaaccat gtgaatcact ataagtgccc      900

tctgtgtgac atgacctgcc cgctgccttc ctccctccgc aaccacatgc gctttcgtca      960

cagtgaggac cggcccttta aatgtgactg ttgtgactac agctgcaaga atcttattga     1020

cctccagaag cacctggata cccacagcga ggagccagcc tacaggtgtg attttgagaa     1080

ctgcaccttc agtgcccgat ccctctgctc tatcaagtcc cattaccgca aagtacatga     1140

aggagactct gagccaaggt acaaatgtca tgtgtgtgac aaatgcttca cacggggcaa     1200

caacctcacc gtgcaccttc gcaagaagca ccagttcaag tggccctcag ggcatccccg     1260

ttttcggtac aaggaacatg aagatggcta tatgcggctg cagctggttc gctacgagag     1320

tgtagagctg acacagcaac tgctgcggca accacaagag ggatcgggcc tgggaacgtc     1380

gctgaacgag agcagcctgc agggcattat tctagaaaca gtgccagggg agccaggacg     1440

taaggaagag gaagaggagg gcaagggtag cgaagggaca gccctctcag cctctcagga     1500

caaccccagt tctgtcatcc acgtggtgaa tcagaccaat gcccaaggcc agcaagagat     1560

tgtctactat gtgctgtctg aagccccagg ggagcctccc ccagcccctg agccaccttc     1620

agggggcatc atggaaaagc ttcaaggaat agctgaggag ccagagatcc agatggtttg     1680

aaggccgcag agccagacca tttcttcccc aggtcctgaa gtttgagcca ggcaagtggc     1740

agtgccccta gtgggcagcc gttgccaatg gatgccttta ggagtggtgc cgagagcagt     1800

gtggtccact ctggcctggg tttgcatcat tctgcagact ctaaagactt cccttttctg     1860

ccagactaca ttttgtgggg agcctgagga ctctggattc tttgagggga tcctggatgt     1920

gtgtgttctt gttaaagagg ctgttatcag gcttaaccat aaccctcaag atctgcttga     1980

cagtgattaa atccttagct cacatccatt cccatctttc gggctcctta ggcccaagga     2040

tggcatgtga ctggtccctg caagggtcct ttctttgtca ccagccaagg cattgataac     2100

caagtagcca ttttcctctt aaggtttcct ctacaacccc aaggactttc atgattatcc     2160

tcagggacag gattggaggc attgagcgtg tttattaaca aattgttttt ggtaataaaa     2220

taaatgcttg gactcttaaa aaaaaaaaaa aaaaaaa                              2257


<210>  1339
<211>  2374
<212>  DNA
<213>  homo sapiens

<400>  1339
ttggctgtca gtcggatccg agaacgacga ttggctttcc ttgaccgtcc ctcaagcgcc       60

tctccggaga tggtctgagg tgggagaaga gctgaagaga cctggagccg acagacgggt      120

ctgggtctgc cgcccaggat ggagtacaat ggtgtgatct tggctctttg caacctctgc      180

ctcctgggct caagccttcc tcccacctga acctcccaag tagcgggact gcagggtgaa      240

ggccatgccg cctcctggga aagttccccg aaaggagaat ctgtggctac agtgtgagtg      300

ggggtcctgc tcctttgtgt gctcaaccat ggaaaagttc tttgagcatg tcactcagca      360

cctgcagcag cacctgcatg gctctgggga ggaggaggaa gaggaagagg aggatgaccc      420

acttgaggaa gaattctcct gcttgtggca ggaatgtggc ttttgttctc tggacagttc      480

tgctgacctc atccgccatg tctacttcca ctgctaccac accaagctga aacagtgggg      540

gctgcaggcc ttgcaaagcc aggctgacct tggcccctgc atcctggact tccagagccg      600

gaacgtcatc cctgatatcc ctgaccactt cctgtgtctg tgggagcact gtgagaattc      660

cttcgacaat cctgagtggt tttatcggca tgtggaagca cacagtctgt gctgtgaata      720

cgaagcagtc ggcaaggaca acccggtggt gctgtgtggc tggaaaggct gtacctgcac      780

cttcaaggac cgcagtaaac ttcgagagca cctccgcagc catacccagg agaaagtggt      840

agcctgcccc acctgtgggg gcatgtttgc caacaatacc aagttcttag atcacatccg      900

tcgccagacc tcattggatc agcagcactt ccagtgttct cactgttcca agagatttgc      960

cacagagcgg ctattgcggg accacatgcg caaccatgtg aatcactata agtgccctct     1020

gtgtgacatg acctgcccgc tgccttcctc cctccgcaac cacatgcgct ttcgtcacag     1080

tgaggaccgg ccctttaaat gtgactgttg tgactacagc tgcaagaatc ttattgacct     1140

ccagaagcac ctggataccc acagcgagga gccagcctac aggtgtgatt ttgagaactg     1200

caccttcagt gcccgatccc tctgctctat caagtcccat taccgcaaag tacatgaagg     1260

agactctgag ccaaggtaca aatgtcatgt gtgtgacaaa tgcttcacac ggggcaacaa     1320

cctcaccgtg caccttcgca agaagcacca gttcaagtgg ccctcagggc atccccgttt     1380

tcggtacaag gaacatgaag atggctatat gcggctgcag ctggttcgct acgagagtgt     1440

agagctgaca cagcaactgc tgcggcaacc acaagaggga tcgggcctgg gaacgtcgct     1500

gaacgagagc agcctgcagg gcattattct agaaacagtg ccaggggagc caggacgtaa     1560

ggaagaggaa gaggagggca agggtagcga agggacagcc ctctcagcct ctcaggacaa     1620

ccccagttct gtcatccacg tggtgaatca gaccaatgcc caaggccagc aagagattgt     1680

ctactatgtg ctgtctgaag ccccagggga gcctccccca gcccctgagc caccttcagg     1740

gggcatcatg gaaaagcttc aaggaatagc tgaggagcca gagatccaga tggtttgaag     1800

gccgcagagc cagaccattt cttccccagg tcctgaagtt tgagccaggc aagtggcagt     1860

gcccctagtg ggcagccgtt gccaatggat gcctttagga gtggtgccga gagcagtgtg     1920

gtccactctg gcctgggttt gcatcattct gcagactcta aagacttccc ttttctgcca     1980

gactacattt tgtggggagc ctgaggactc tggattcttt gaggggatcc tggatgtgtg     2040

tgttcttgtt aaagaggctg ttatcaggct taaccataac cctcaagatc tgcttgacag     2100

tgattaaatc cttagctcac atccattccc atctttcggg ctccttaggc ccaaggatgg     2160

catgtgactg gtccctgcaa gggtcctttc tttgtcacca gccaaggcat tgataaccaa     2220

gtagccattt tcctcttaag gtttcctcta caaccccaag gactttcatg attatcctca     2280

gggacaggat tggaggcatt gagcgtgttt attaacaaat tgtttttggt aataaaataa     2340

atgcttggac tcttaaaaaa aaaaaaaaaa aaaa                                 2374


<210>  1340
<211>  1906
<212>  DNA
<213>  homo sapiens

<400>  1340
agtgacgccc ccgaacccag ctgcagaagc tgccgccacc tccaatgcac aaggtgtctc       60

atctgaaaag aaacctgagc cccagggagg cggcgcggag cgaccctggc agagctggcg      120

caaacagggc gagaggtcgc tgggcagcgt tcgaggacca gagggagctc ggccacagaa      180

gaccccagtg atctgatccc gggatcccgg ctccaagctc tcctcgcatt ttacagattt      240

cacccccgcg actatctccc caaaacggag cctttatatc aagagaaggt gcgggagctg      300

gggcaaccag gactttctcg ggcacccaag atgcgctcca ttaggaagag gtggacgatc      360

tgcacaataa gtctgctcct gatcttttat aagacaaaag aaatagcaag aactgaggag      420

caccaggaga cgcaactcat cggagatggt gaattgtctt tgagtcggtc acttgtcaat      480

agctctgata aaatcattcg aaaggctggc tcttcaatct tccagcacaa tgtagaaggt      540

tggaaaatca attcctcttt ggtcctagag ataaggaaga acatacttcg tttcttagat      600

gcagaacgag atgtgtcagt ggtcaagagc agttttaagc ctggtgatgt catacactat      660

gtgcttgaca ggcgccggac actaaacatt tctcatgatc tacatagcct cctacctgaa      720

gtttcaccaa tgaagaatcg caggtttaag acctgtgcag ttgttggaaa ttctggcatt      780

ctgttagaca gtgaatgtgg aaaggagatt gacagtcaca attttgtaat aaggtgagct      840

ttcttctgct ttttgagatt gtaagttttt caaagatatt ttacttgggg gtggaaaact      900

gttagaaaat tttaaagtat tactaaaacc tcaaacaaat atttgtctat gatatccttt      960

tctgtgcaac atttaaatta catttaccct ggaatagaat attataatta ttgcgtagtt     1020

gaaagaaaaa gtgatcctgt catagcaaca agattcacac agcttttttt ggtgaggtga     1080

ggggggaggc aaatggcaat tttattaaat ttaatattcc acacaaactt ttttcttagt     1140

atctcttctt catactcatt agttttgtgt gattttattt gttgtataaa gattatgaat     1200

attactatgg aatgatgtaa tagatttatg ttaatgttac tttttattaa taattatcta     1260

ggagatagta agaacatagt ttagcaagtt tatatttgat atcctgagcc atatttcttt     1320

aatttctctt tatatgtggt atttgtgtat gttagtatat ttgaatttta tgttttttta     1380

acataattaa gcgtgcatgt ttgtttttca ttaacggtta aaagatattt gatgaattgt     1440

gtgtttgatt aacctattaa ctgaaaaaaa ctcaacagta gaaatggaat tataatcaca     1500

tcataaatat aagcagtttt taatgatcaa tttttatatc tgtacagttt ttttggattg     1560

ttttagttcc ttagaaaaat tagctaaatg acagaaacat ggatattgaa atatgaaata     1620

gtacaatata aagatagata gaaaagtatg ctgagttgac atgttgaaaa acacagtctc     1680

ttgaagatat actggaatac attatttttg aatattttga atattttttg aatattttta     1740

aataaagtct taaaagcata aataggtaac tacttttaaa aaaaaagtca tgagaaatca     1800

cactcaagca ttatcaagtg aagaaaattc ataatagcaa ataaaactgc aaacatttta     1860

ccttaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                    1906


<210>  1341
<211>  6332
<212>  DNA
<213>  homo sapiens

<400>  1341
agtgacgccc ccgaacccag ctgcagaagc tgccgccacc tccaatgcac aaggtgtctc       60

atctgaaaag aaacctgagc cccagggagg cggcgcggag cgaccctggc agagctggcg      120

caaacagggc gagaggtcgc tgggcagcgt tcgaggacca gagggagctc ggccacagaa      180

gaccccagtg atctgatccc gggatcccgg ctccaagctc tcctcgcatt ttacagattt      240

cacccccgcg actatctccc caaaacggag cctttatatc aagagaaggt gcgggagctg      300

gggcaaccag gactttctcg ggcacccaag atgcgctcca ttaggaagag gtggacgatc      360

tgcacaataa gtctgctcct gatcttttat aagacaaaag aaatagcaag aactgaggag      420

caccaggaga cgcaactcat cggagatggt gaattgtctt tgagtcggtc acttgtcaat      480

agctctgata aaatcattcg aaaggctggc tcttcaatct tccagcacaa tgtagaaggt      540

tggaaaatca attcctcttt ggtcctagag ataaggaaga acatacttcg tttcttagat      600

gcagaacgag atgtgtcagt ggtcaagagc agttttaagc ctggtgatgt catacactat      660

gtgcttgaca ggcgccggac actaaacatt tctcatgatc tacatagcct cctacctgaa      720

gtttcaccaa tgaagaatcg caggtttaag acctgtgcag ttgttggaaa ttctggcatt      780

ctgttagaca gtgaatgtgg aaaggagatt gacagtcaca attttgtaat aaggtgtaat      840

ctagctcctg tggtggagtt tgctgcagat gtgggaacta aatcagattt tattaccatg      900

aatccatcag ttgtacaaag agcatttgga ggctttcgaa atgagagtga cagagaaaaa      960

tttgtgcata gactttccat gctgaatgac agtgtccttt ggattcctgc tttcatggtc     1020

aaaggaggag agaagcacgt ggagtgggtt aatgcattaa tccttaagaa taaactgaaa     1080

gtgcgaactg cctatccgtc attgagactt attcatgctg tcagaggtta ctggctgacc     1140

aacaaagttc ctatcaaaag acccagcaca ggtcttctca tgtatacact tgccacaaga     1200

ttctgtgatg aaattcacct gtatggattc tggcccttcc ctaaggattt aaatggaaaa     1260

gcggtcaaat atcattatta tgatgactta aaatataggt acttttccaa tgcaagccct     1320

cacagaatgc cattagaatt caaaacatta aatgtgctac ataatagagg agctctaaaa     1380

ctgacaacag gaaagtgtgt aaagcaataa agcacatttt gaaacaaaca atatgcactt     1440

cttttctgaa gatgcttccg aagatttgaa aataggatcc aaaacacggc tgggtttcag     1500

catccaccaa tgaactgaaa ggtgaataaa ggacgttcat gagaaatcga ctaccagctg     1560

atgaaatacc tgcaaagtgc tctaaaaatt aaatattttg actttaaggg tcctagtaag     1620

tgccacttcc actaagaata cagtttgaat gtataatcag tagtgtttac aagatccaac     1680

agtgcactca tcattagtta acaaagcaaa tatgttcatc actgtcaggc tgcccacagc     1740

aacaccaagc atattagaag aggaacccca ggaacgcaac tcagaccttg ggaaattaaa     1800

ccatccttgt cagcagaagc caagatggaa gcagtttgag caatgaaatc cgtaagatta     1860

aacaactcaa gtaaatgctt cagtcaggac tctgagtctg atcatgaatt ttatgtttta     1920

atttatgttt tttttttgtc ttctggaatc tcttttggtt tggatattgg gatgcttaga     1980

aatcctttct gagatgcata tgagtgagga aataaacttt aagtaattat ttttaaagtt     2040

cttatacttt ttaaaagcta tcacacaaag actttttttt ttttttttgt ctcgctctgt     2100

tgcccaggct ggagtacagt ggcgcgatct cagctcactg caagctccgc ctcccaagtt     2160

cactccattc tcctgcctca gcctccggag tagctgggac tgcaggcgcc tgccaccacg     2220

cctggctaat tttttgtatt tttagtggag acggattttc accgtgttag ccaggatggt     2280

ctcaatctcc tgacctcgtg atccacccgc cttggcctcc caaagtgctg ggattacagg     2340

cgtgagccac cgtgcctggc cgacattttt aaaaaagttt tattttgcac ggctctaaac     2400

ctccatgtta ttttccagtg gtgtagaagg taccagctaa agtgaaccac tatgtaatat     2460

taggccattc taaaggaaag atgttccatg tcatcagaga tggtaaaata ggccgggaaa     2520

aaaaaatctt tggtaccaaa gattacactt gtgtttctac acagcaaacc atttttcttt     2580

catgaaaata atatattatt aacatgaata tattattttg ctattaatgt gaaagttgtc     2640

tctaaatatt ttttaatttt caaactcata ctttattttc atttgaaatg tttttcacac     2700

cttttgcatt acataataat tttgtggaag cattttgccc tttagaataa atattagatt     2760

gatatagctg aaatgtgact tccagttctt tgatattccc cttgttattc aaatagaaat     2820

atggaaatgc tttatatatt actgttaaat ttcttagtgc agaaataaca ttattaatag     2880

agtattgttt tcaaaacaga gatgattaat ttcaagaggt ttaacagtga aattgtgtca     2940

atattttgca tttaaaatga atttaattga ccgatatttt ctgtagttaa atttagtcac     3000

aatatcacat atgttcttca agaaacacat gaaattatta ataaagtaat taaaaaattt     3060

ttaatgtata acagaattga ccaataggcc agttttctgg taacttatga tagtagattg     3120

tttctttaga aactgggcag aagctctgca ttctcacttg tactttgatt tcttatttct     3180

tgggcaggca atttgaggaa agaagaaatg gcatggggaa tatatatgtt ttgtttctta     3240

gggaaaacag tctgagaaat gaataaaaag catgaagtac gtgtgtgtgt gtgtgtgtta     3300

ccatggaaaa ggatattcac agtagtacag ttctcaatat ttttaattag atgtcatatt     3360

tttttaatat agtaaaacct tgggatatag aatattacat cttttgagaa tgtatgtgtc     3420

tctaagtaag taaaatctaa tgcgtatagg agactgatag ctaaaaatga atggaacatt     3480

aatgtacttt tataattaaa cctcttatct atcagaaatt gtaagagaat agatacatgt     3540

tttgaatgta aagttgaaaa gtctggttta cttaataaat tgaaagtgat ttataaaatc     3600

taaatttgga ctacttgcaa atgataagct attctagtag cctttagttt aaatccaaca     3660

gaaatctaga agtcacaagc aaatatctta aaggtaaaat ccatctgggc actcatttaa     3720

agtatatctt aaaaaagcag cagcaaggta ccttgccatt tttagcatat tttcttcctt     3780

tttctttttt cttttttttt tttttttgag atggagtctc actctgtcac acaggctgga     3840

atgcagtgat gccatctcag ctcactgcaa cctccacctc ctgggttcaa gtgattctcg     3900

tgcctcagcc tcccaagtag ctggggttac aggcgcccac caccacactc ggctaatttt     3960

gtgtttttag tagagacaaa gtttcaccat gttggccagg ctggtcttga acttcctgac     4020

ctcaggttat ccacccacct cagcctccca aagtgctggg attacaggtg tgagccaccg     4080

cagccggacc atttttagta tattttcagt aaatacattt aaacaatgtt aaggccacag     4140

cacacatatc tcagccattc attgttctgt gcattgatgt ttatctcata gatgcattga     4200

gtagtgcctt tttagctttt tcacattact ttgtcaccat atcctttgtg ttctctaaat     4260

acattgccca cttccaaaaa tgttcagcat gaaaaaaagg gcttcagtgt cgattgagat     4320

tgcttttgtt catctcaggg atttcaatag tcaagaatga attcagttaa aggtatttag     4380

ggttcaaaga agacaaactg tacaagccca tttcattcct tgttgtatac ctttccatct     4440

gccctcccat tttaactatc tactgtggcc tttttatgga aacagagcaa gatcaatgaa     4500

ggctaatggc aagaataaga aaaagagttg agatttaacc aatagcggag cataaaggat     4560

catgacaaaa tcaaattata aaagcatact tgaaataggt ggagcttttt cttttgaaaa     4620

tatatattca caattttaat attttaattt attttttact atttaaccct gtacttggca     4680

atgctcaggc agctgattgt gaaatattct tgtcctttac agaacatggt tgttattgtg     4740

ctgttgacat gaatagacca tggaaacatt ttcatcatta ttattcagcc tgtgctgtag     4800

ttaatgttaa gttgctgaaa taaaaagtga gcaagtaata gattttcttg gcaaatctaa     4860

tgattcagcc cacaggactg ttgaaactac tgcggaagtt tttctatctg aaagaaggtg     4920

ctgggcattc aaatgtgttc atgtattgta tatcatatga attgtatatc aattactaat     4980

gggaatttct acatatatgc ttacaaaagc aatttattta agtaatgcta ggggtagtgt     5040

acataccaat tagttattca gctactatac agaaaaagga tgaacaaatt aatttatttc     5100

taattgagcc agttagacat aatgcatata acgtgatatt tggttcatga aagagttgtt     5160

ttcatgtggt tattgtaggg agtatatata attgtggaag gggtatggga agagttgtgt     5220

atagttagtt gttatctcta caagtttgaa agttttccca tcaaacatta tcaatatacc     5280

aatgttttaa aaattgagtg agggttatta tttgtatttg atgaaagaaa atccaaataa     5340

agcccaccta gaaatagata ttttattata tatgtgctat agatatacct atatagtaca     5400

aatagacatg tgtgatgcat atatacaatg ttatatatgt gtatatgtct gtatacacac     5460

tgagtctgta atatgtatac actaaatttg tgttatgcta acatcttcag ggtctgcact     5520

gtgaactccc ctggagataa gtaagtccac tttagaataa agaagttctt ttgagacttc     5580

agttactaac gtgctttaag aggtatctac tttataactg aattctatgt cgttcatacg     5640

tagagttaca gtaagggtct agtatgtcca aatcttaata ataaagaaga aaagtaaagg     5700

cttcaagcta gcaatgtatt cgaattacag ttttcagatt gtggctccag gccttgtgtt     5760

tctcatttaa gtagcacctt ttaataaaaa ccgtttcttt gtgtaggcaa aagcacaagt     5820

gtttcaaatg taaatagcag gaaaaaaaaa gagtttacag agatagcatt gctgcacaga     5880

ataattgcta ctgagtattt cttatagaat ttgtggaact gaaagatgag gtttattctg     5940

tcaagttcaa gttcattctg ttcaacactg ttttcttatt gtttgtgtat agcaaccggg     6000

tattattgtt ttatcatttg taaaattgta aaataaatta atcccttttt ttcactgttt     6060

ctcttatctc atatatccaa gcccttggtt atactttgta tgtcaatgtt aggtgatcat     6120

ttttaacaag ctttggcttg tgctttgctt ttccactccc cttagcccta gtggttggca     6180

attaggcaaa ccatttattt ttaagtgtat acatgggaat atgaacaatg tcaaaaaccc     6240

catgaatatt aggaaatcct taacgatatt ttgtgtagca cattctgttt gcggttgagg     6300

gaataaagta tttcacaagt gaaaaaaaaa aa                                   6332


<210>  1342
<211>  9262
<212>  DNA
<213>  homo sapiens

<400>  1342
tagagagatt ggttttcttt ctctcagcat ctccacccaa ccagcagaaa accggtgagt       60

ggggctttta agtgattttc aagaagaatg taacagatgt caaacgggaa aagcacaagg      120

caaagcctgc tctctctgtc tctctgtctc ctcttctcct tttttgcctt attctatccg      180

attttttccc taagcttcta cctgggattt tcctttggaa aagtctctga ggttccacca      240

aaatatggaa cttgattttg gacactttga cgaaagagat aagacatcca ggaacatgcg      300

aggctcccgg atgaatgggt tgcctagccc cactcacagc gcccactgta gcttctaccg      360

aaccagaacc ttgcaggcac tgagtaatga gaagaaagcc aagaaggtac gtttctaccg      420

caatggggac cgctacttca aggggattgt gtacgctgtg tcctctgacc gttttcgcag      480

ctttgacgcc ttgctggctg acctgacgcg atctctgtct gacaacatca acctgcctca      540

gggagtgcgt tacatttaca ccattgatgg atccaggaag atcggaagca tggatgaact      600

ggaggaaggg gaaagctatg tctgttcctc agacaacttc tttaaaaagg tggagtacac      660

caagaatgtc aatcccaact ggtctgtcaa cgtaaaaaca tctgccaata tgaaagcccc      720

ccagtccttg gctagcagca acagtgcaca ggccagggag aacaaggact ttgtgcgccc      780

caagctggtt accatcatcc gcagtggggt gaagcctcgg aaggctgtgc gtgtgcttct      840

gaacaagaag acagcccact cttttgagca agtcctcact gatatcacag aagccatcaa      900

actggagacc ggggttgtca aaaaactcta cactctggat ggaaaacagg taacttgtct      960

ccatgatttc tttggtgatg atgatgtgtt tattgcctgt ggtcctgaaa aatttcgcta     1020

tgctcaggat gatttttctc tggatgaaaa tgaatgccga gtcatgaagg gaaacccatc     1080

agccacagct ggcccaaagg catccccaac acctcagaag acttcagcca agagccctgg     1140

tcctatgcgc cgaagcaagt ctccagctga ctcagcaaac ggaacctcca gcagccagct     1200

ctctaccccc aagtctaagc agtctcccat ctctacgccc accagtcctg gcagcctccg     1260

gaagcacaag gacctgtacc tgcctctgtc cttggatgac tcggactcgc ttggtgattc     1320

catgtaaagg aggggagagt gctcagagtc cagagtacaa atccaagcct atcattgtag     1380

tagggtactt ctgctcaagt gtccaacagg gctattggtg ctttcaagtt tttattttgt     1440

tgttgttgtt attttgaaaa acacattgta atatgttggg tttattttcc tgtgatttct     1500

cctctgggcc actgatccac agttaccaat tatgagagat agattgataa ccatcctttg     1560

gggcagcatt ccagggatgc aaaatgtgct agtccatgac ctttcaatgg aaagcttagg     1620

tgcctgcgtt atatttgccc tgtctaattt tgcccataca gtcttccttc tgtagagggc     1680

tgtttacata tacagcactt aaaatgtttg tgtgggaaaa aaaaaactca ttggcagatc     1740

caagaatgac aaacacaagt gccccttttc tctggatctc aagaatggtg gaggaccctg     1800

gaaggacagc aaggcagctc cccagcctca ctcttcactc ctgattgagg cccgggtttg     1860

ttgtccagca ccaattctgg ctgtcaatgg ggagaaataa accaacaact tataattgtg     1920

acaccagatg cttaggatcc tggtgctggg ttagctaaga gaatagacag aattggaaaa     1980

tactgcagac atttccgaag agtttataaa gcacagtgaa ttcctggtca atctctccac     2040

tgaggcaatt tggaatcaat aagcaattga taatagtttg gagtaaggga cttcatatac     2100

ctgattcctc tagaaggctg tctaacatac cacatgatta catgaactgt atggtatcca     2160

tctatctctg ttctattgaa tgccttgtta acagccaaca ctgaaaacac tgtgagaatt     2220

tgttttcagg tctgacacct ttcagtctct ttttatagca agaaatcaat atccttttta     2280

taaaaattca tgtctgtatt tcaggagcaa actcttcagg ctcctttttt ataaactggt     2340

gatttttctt ttgtctaaaa aacacatgaa gaaaatttac caaaaaaaaa aaaaaaagca     2400

gaagaataat gtagtttaga aattatgctg tcactgccaa acagtaacct ccaggagaaa     2460

acaagatgaa tagcagaggc caattcaata gaatcagttt tttgatagct ttttaacagt     2520

tatgcttgca ttaataattt caatgtggac cagacattct aattatattt taaatgaaat     2580

gttacagcat attttaagca actcttttta tctataatcc taatatttca tactgaagac     2640

acagaaatct ttcacttgtc tttaacatta gaaaggattt ctctttacta aggactgatc     2700

atttgaaata gttttcagtc ttttgagata caggtttata acactgcttt tttttttctg     2760

taatcatagc ccataatggc aaagacaact aaatttaagt gaaggtcatg catgccaatt     2820

ctgtgtttgc ttttagcaga tatgaagatt tccttatttc tttgtaattg tgcagatatt     2880

ttgaaaggca cagcattcga agccaagctg ctgtttggct actgaatggc ttgcagttgt     2940

tcctccactc taaatggaat gagcttgctg tgtgtgtgtg tggtggtggt gggagggggt     3000

ggtgcatgtg tgtgtgtgtg tgtgcatctg cagctgcttc aaaattagga aatactacag     3060

gacacccctg taatggattg gtggcaactg ggtggcactg ctgatgtgca ctgtgtaggg     3120

gggaacccag tggtggtggg gtagctcaga tgcccctaga caagcttcag atgtctgtag     3180

ctaccagaaa cattttcggt tcaggaaaag tgagatgatg gtagtactgg tttctggtga     3240

aattgaagaa ccccaaatga tgaggatctc tttttgcccc ctctcctttt tttgtagacc     3300

cattcaaaac cattaataag cccattttac taagccccta tttctttcta gaagctcagg     3360

gttttcttag tgcctcccag aacattttgt agttaattgg gaaaaagtga tacttggatt     3420

agggggtgtg ggcataaaga atggtgggag gcctgatttt aaacttcagg ccagaacccc     3480

caatgactcc acccatagtc tcactttagg tctcatttag tccatcacct ttattttaag     3540

ttgaggaagt ggaggctggt aaagagcagg accagaggaa gaatccagat ttccttatgc     3600

ttgggcctca cactagctct ctgagtattt ccttgattgc ggtatatgta ctactagaaa     3660

ataccaaatg gatatatttt ctttaggata acctttgaac caacaatctt caataacaat     3720

agtacatctt ccatcttact tttaatcgag tataaggaaa tgtttcttta tggccatttt     3780

ggagggagca ggggatgagg cttggcatag tccaaaattt aagtctccaa taattaattg     3840

cattttaaat tggcccactt tcaaggcaat tttttttgtg tgtctgtaac tgagctcctc     3900

cacccctgtc attcacttcc aattttaccc aatccaattt tagcactcaa gttccattgt     3960

gttaatttct gcacggtcaa caaacatcaa gtcagcaagc atttgccacc actccctata     4020

cttctccctc cttcttacac acacacacac acacacacac acaatccatc tcttgcttgt     4080

tcctacctcc tgatttttct tccctacaga aatagaaata gggacaaaga aggggaaaat     4140

gtatatattg gggctgggct gaacaactaa cttcataagt agtattaact aggggtaaat     4200

tgagagaaaa gctccttttc tcttcactgt tttggaaagg atagccatta gcatgactgc     4260

tttgtgtcct tatggacttt agtattagcc tagattgaat tatagcgttt tctagctgga     4320

aggaacctta agatcacatc atctactcct ctactccaaa tttctcattc ttcaggccag     4380

gaaaccgaga cacagaggta aagtaatttc cccaaggtca cacagctggc tggggcagga     4440

ttgggtttac aacccacatc tcctggctct tattccaggg ccttttccca ctaagtagta     4500

ttgccttcca ttaggctcct gagagttatt tctcagggtc atgttgcatc ttggagccac     4560

atgctgctgc cctgatctca gtgggaaatc cacccagcaa cctaatacag ccccttttcc     4620

ctgcattcac ctggttccca tccacatggg ttgcagatgt ccttgaagag agtgaggcat     4680

tgagggccaa taggagcaat ggggtccctg gccttgtcca tctgattcag gagatcactg     4740

ctccatcgtg aggagccctc tgaatagccc cccactgaat gcttgccttg cccaaatgga     4800

atggaggaag attgattttc tccatcagtt caccttgtgt catctcataa tggttggtct     4860

ttccaggctg agggaaatgt ttcttgtttc cagagtagaa aaagaaagag tggaacaata     4920

gctttgttca tcctaacttt ctgagatggc ttttcaacat tttaaaaaaa ctagtgtggc     4980

taccattcac tggcaatgat ttcttttaga atatgggagt aagatgagct agagaaaata     5040

acctggtctc actgtggttg ccctcatcca caatgtcccc aaagccatcc tgctctgatg     5100

aggacaattt ccaggtataa gcaaggggct ttgtgacaaa aatgtaccct ggctgatgtt     5160

aaacattggc tcctgtgttt gcaccaaaat agcaagctgt gtgctctata cactcttccc     5220

atcgtcttgt gtacactgct cctgtggcct tccacagcag aaaccagggc aaaagggtcc     5280

aaacacatgg ttttccttgc tgcaaggctc ttcctgggaa ctaagggggt atttattagt     5340

tcagttctaa gagacctcct tctgggctta ccccactcct caggtacttc tctctccttc     5400

ctccttctcc tccacagtca caagtaacca aggaacctga aagtggatgt gtagctattt     5460

gaagaaggca aggaaccctg agattcttct ttgaatcctc tagtccaagt cttagaccag     5520

tgattggtgc ttaccttgaa caaaattttg tctgtgttcc taatcccttc aatactctgg     5580

gtacaatgct cccaatcacc ctgcacattt gattctaaat ggcttttatt ttttaaaaat     5640

ccatatccct aggacaagag aacaggatgc ctatatcccc aaaatgagct ccaggacact     5700

gatgggaatg atcccaaaga tcaccccacc tcagaaacgt ctgtgccaag agacttcccc     5760

agatagaaac actgggacag tggtttgaac gacttctttt atggttgtcc agtttgctat     5820

ggaaataaaa ggcattgatt ttttaaaaag atgattggaa cctgtctttg gccacatagg     5880

gccacttgga tccatttcca ggccttactc atatattgcc ttcactgaag ggctttggct     5940

ttaagtccca gactggtctc ccaagtgaac cataagtgtt ttggagctca tctggggtga     6000

ggcatgagaa tgttgcccca tctatccctt caggaaaagg tgccttccct ccctttctcc     6060

taaagcctgg tccccagaaa ttgtttttgt ctccaaaagt ctagtatggt ctttatacac     6120

ccagactctt agtgttgcgt cctgccttgt ttccttgtta aggatctatg cagacctccc     6180

gctttggctt agctagcgtg acattggcta tcatttgaca agactaactt tttttttttt     6240

ttttttttga ctgagtctcc ctctgtcacc taggctggag tgcagtggca caatcttggc     6300

tcgctgcaac cttcaccctt cacctcccag gtcgaagcga ttctcctgcc tcagtctccc     6360

gagtagctgg gattacaggc gtgcgccacc aaatctggct atttttttat tattattatt     6420

tttagtagag atggggtttc accatgttgg ccagactggt cttgaactct tggcctcaaa     6480

ttatctgccc acctcggcct cccaaagtgc tgggattaca ggcatgagcc accatgccca     6540

gctgacaaga ctaatttttt atcccttggt ttattggctt caacatcttc tggaatcaga     6600

ggtgattttt tcttaccttg gatgcctgag actaggggag tatagaattc caattggtaa     6660

ttaaggcatc tttctgctcc tgatcagaag ggcaggttag ttgggagagg tcagatggca     6720

caacagaagt caccttgtaa gtaaggcaaa gacttgaagg cattagcgtt tctcattact     6780

aggtcaataa cctgagggaa tcaatggctt tttgccgctc tacctcttgt gtatctcttt     6840

gacttttctt tctctgtcta gtttcctctg ttctcagttt atattctatg ttatcagtct     6900

ctctttccac agtacaaaca tccatccttt ctcctgtgca attctgtctc tccctcttat     6960

tatctttatt tgtacttttt ccttcctccc tgtctaggca ttgggcatgt gcctcttctt     7020

agcctgtgat tttgccttgg gactgatgat aaattatttc cagattcaat cagccctggt     7080

cctaccccag tccaatcaga agtatgttgg tgggaatcaa cctgatcctg gccctttctt     7140

cttctccatt ttcattcgta atccccctca gcagatcttt acaagcagtt tccttatagc     7200

tcatgtatct ttaggtcttt gccttccaag cactgtacag aatactttgt ggttcctttt     7260

tagtctgaca ttttgtggag cagtgaagcg tgctcagaga cataatcagc tgaagagaaa     7320

aaatccaccc atggatttat atcagctaaa tactaataat tgattttgtt tgatgtgccc     7380

ataattttta aagctgcaat ataatataat gagggaccac aggtaatttc tcctgtcatt     7440

tgttttggct ggatgggggt gggggagtaa ttgcttaaag ttttaccatt acacattaaa     7500

ctctctataa taatcttgtt tggggcttgc taactgttga gctgttttaa ctaaactggt     7560

aggcaatcgg agttgattta aatgaaaaga taatttaaca aatctatact ataaaaagag     7620

acatttgctt aattgacatg tattttttcc ttctgagtca cctaaacatt tactcttgac     7680

accaactgtt catgatactg aatagacagt ccatataaga gaaattagtg gacctaaaga     7740

agccagattg taggtgttaa tttattaaac agagtgcaaa gcccttggaa atgtcactgc     7800

ttggcaatac catatggaat gccaaaattt acaatgactt ttctttataa gttatccaaa     7860

agggatttga acaagtaaga ggttatgcca aaatgtctcc aatgtatggt cctgtaatat     7920

attgcagctt gaagccaatg atcccttatg acttgtatac aactaatgca tgttttattg     7980

aattttgcat ttcccacgtg tggtaagttc tttaaaatgt ttttgatcac ctttttgtgc     8040

cattaaactt gtacagaaaa tgtttttatg gccattttca aagggagaaa gtttaaaatg     8100

gaaacagccc accctttctg ccctatagct gtagttagaa ttgagtacct gtagcaaaac     8160

agctgtaatt ggtggttgta gtgttagagg tgttagcttg ctagtgacta gctttggaga     8220

gtaaatgcat ggtattgtac atcacatttc ttaactcgtt ttaacctctg aaaagaatat     8280

attcttcttt gtagtccttc ttcccacccc cttgccctct ccctctccct gctcccagtt     8340

gtcttacagt tgtaaatatc tgatttgagg cccaataact cttgccaagt aaagtcagca     8400

aacaacaaac aaaccaaaat gtggggaaaa ggcatttctc aaccatctct cagcagttat     8460

tgatcatttc ttaaggaaca gcattgtgat caaagactca actttacgta aaaatcagtg     8520

gtaaattggg gttgtatttg gccatttgat tacatttcag gattgaatag ttttcagaat     8580

cacatgtaat ccaaagacag taggtagtga tgtcccttat ccctgcagct gttttaagat     8640

agagacctca gaagactctg cttgaccgat gaccaataat tatttgaaaa aaaaagaaaa     8700

aatgagagaa ataaaacaga tatttaagaa ctttagccac ctatttagaa tagttatagc     8760

cagaaaaaaa aacaagggca tgagttcaaa tgcattacta tcagtgtcct aggcaatacc     8820

taacctactc tgaaattgtg attcaaaagc agtatttcaa gaggcattct ccttttttgg     8880

tttgctgacc ccacttggac tggtaggttt ggtgaggccc ccataaacca gctggagcag     8940

acccttttca tctcctgtgc ctgtaacacc cctcttcccc caccccctcc gcaattcaat     9000

gagggctttc ttgggtcaga ggacttcaag gttgtctaga gaagtttgcc atgtgtgtaa     9060

ggtgctgtga actgtgagtg ctgaagattc gcagcattca ataccaggca gccaaagagc     9120

tgctcttgca attattttgg ctctcaagct ctgttcttca tcgcattctc atttctgtgt     9180

acatttgcaa gatgtgtgta atgtcatttt ccaaaaataa aatttgattt caataaaaaa     9240

aaaaaaaaaa aaaaaaaaaa aa                                              9262


<210>  1343
<211>  9150
<212>  DNA
<213>  homo sapiens

<400>  1343
ctggcaggaa tttcttgctt ggagctcaga caacaaaggc atagagagat tggttttctt       60

tctctcagca tctccaccca accagcagaa aaccggtctc tgaggttcca ccaaaatatg      120

gaacttgatt ttggacactt tgacgaaaga gataagacat ccaggaacat gcgaggctcc      180

cggatgaatg ggttgcctag ccccactcac agcgcccact gtagcttcta ccgaaccaga      240

accttgcagg cactgagtaa tgagaagaaa gccaagaagg tacgtttcta ccgcaatggg      300

gaccgctact tcaaggggat tgtgtacgct gtgtcctctg accgttttcg cagctttgac      360

gccttgctgg ctgacctgac gcgatctctg tctgacaaca tcaacctgcc tcagggagtg      420

cgttacattt acaccattga tggatccagg aagatcggaa gcatggatga actggaggaa      480

ggggaaagct atgtctgttc ctcagacaac ttctttaaaa aggtggagta caccaagaat      540

gtcaatccca actggtctgt caacgtaaaa acatctgcca atatgaaagc cccccagtcc      600

ttggctagca gcaacagtgc acaggccagg gagaacaagg actttgtgcg ccccaagctg      660

gttaccatca tccgcagtgg ggtgaagcct cggaaggctg tgcgtgtgct tctgaacaag      720

aagacagccc actcttttga gcaagtcctc actgatatca cagaagccat caaactggag      780

accggggttg tcaaaaaact ctacactctg gatggaaaac aggtaacttg tctccatgat      840

ttctttggtg atgatgatgt gtttattgcc tgtggtcctg aaaaatttcg ctatgctcag      900

gatgattttt ctctggatga aaatgaatgc cgagtcatga agggaaaccc atcagccaca      960

gctggcccaa aggcatcccc aacacctcag aagacttcag ccaagagccc tggtcctatg     1020

cgccgaagca agtctccagc tgactcaggt aacgaccaag acgcaaacgg aacctccagc     1080

agccagctct ctacccccaa gtctaagcag tctcccatct ctacgcccac cagtcctggc     1140

agcctccgga agcacaagga cctgtacctg cctctgtcct tggatgactc ggactcgctt     1200

ggtgattcca tgtaaaggag gggagagtgc tcagagtcca gagtacaaat ccaagcctat     1260

cattgtagta gggtacttct gctcaagtgt ccaacagggc tattggtgct ttcaagtttt     1320

tattttgttg ttgttgttat tttgaaaaac acattgtaat atgttgggtt tattttcctg     1380

tgatttctcc tctgggccac tgatccacag ttaccaatta tgagagatag attgataacc     1440

atcctttggg gcagcattcc agggatgcaa aatgtgctag tccatgacct ttcaatggaa     1500

agcttaggtg cctgcgttat atttgccctg tctaattttg cccatacagt cttccttctg     1560

tagagggctg tttacatata cagcacttaa aatgtttgtg tgggaaaaaa aaaactcatt     1620

ggcagatcca agaatgacaa acacaagtgc cccttttctc tggatctcaa gaatggtgga     1680

ggaccctgga aggacagcaa ggcagctccc cagcctcact cttcactcct gattgaggcc     1740

cgggtttgtt gtccagcacc aattctggct gtcaatgggg agaaataaac caacaactta     1800

taattgtgac accagatgct taggatcctg gtgctgggtt agctaagaga atagacagaa     1860

ttggaaaata ctgcagacat ttccgaagag tttataaagc acagtgaatt cctggtcaat     1920

ctctccactg aggcaatttg gaatcaataa gcaattgata atagtttgga gtaagggact     1980

tcatatacct gattcctcta gaaggctgtc taacatacca catgattaca tgaactgtat     2040

ggtatccatc tatctctgtt ctattgaatg ccttgttaac agccaacact gaaaacactg     2100

tgagaatttg ttttcaggtc tgacaccttt cagtctcttt ttatagcaag aaatcaatat     2160

cctttttata aaaattcatg tctgtatttc aggagcaaac tcttcaggct ccttttttat     2220

aaactggtga tttttctttt gtctaaaaaa cacatgaaga aaatttacca aaaaaaaaaa     2280

aaaaagcaga agaataatgt agtttagaaa ttatgctgtc actgccaaac agtaacctcc     2340

aggagaaaac aagatgaata gcagaggcca attcaataga atcagttttt tgatagcttt     2400

ttaacagtta tgcttgcatt aataatttca atgtggacca gacattctaa ttatatttta     2460

aatgaaatgt tacagcatat tttaagcaac tctttttatc tataatccta atatttcata     2520

ctgaagacac agaaatcttt cacttgtctt taacattaga aaggatttct ctttactaag     2580

gactgatcat ttgaaatagt tttcagtctt ttgagataca ggtttataac actgcttttt     2640

tttttctgta atcatagccc ataatggcaa agacaactaa atttaagtga aggtcatgca     2700

tgccaattct gtgtttgctt ttagcagata tgaagatttc cttatttctt tgtaattgtg     2760

cagatatttt gaaaggcaca gcattcgaag ccaagctgct gtttggctac tgaatggctt     2820

gcagttgttc ctccactcta aatggaatga gcttgctgtg tgtgtgtgtg gtggtggtgg     2880

gagggggtgg tgcatgtgtg tgtgtgtgtg tgcatctgca gctgcttcaa aattaggaaa     2940

tactacagga cacccctgta atggattggt ggcaactggg tggcactgct gatgtgcact     3000

gtgtaggggg gaacccagtg gtggtggggt agctcagatg cccctagaca agcttcagat     3060

gtctgtagct accagaaaca ttttcggttc aggaaaagtg agatgatggt agtactggtt     3120

tctggtgaaa ttgaagaacc ccaaatgatg aggatctctt tttgccccct ctcctttttt     3180

tgtagaccca ttcaaaacca ttaataagcc cattttacta agcccctatt tctttctaga     3240

agctcagggt tttcttagtg cctcccagaa cattttgtag ttaattggga aaaagtgata     3300

cttggattag ggggtgtggg cataaagaat ggtgggaggc ctgattttaa acttcaggcc     3360

agaaccccca atgactccac ccatagtctc actttaggtc tcatttagtc catcaccttt     3420

attttaagtt gaggaagtgg aggctggtaa agagcaggac cagaggaaga atccagattt     3480

ccttatgctt gggcctcaca ctagctctct gagtatttcc ttgattgcgg tatatgtact     3540

actagaaaat accaaatgga tatattttct ttaggataac ctttgaacca acaatcttca     3600

ataacaatag tacatcttcc atcttacttt taatcgagta taaggaaatg tttctttatg     3660

gccattttgg agggagcagg ggatgaggct tggcatagtc caaaatttaa gtctccaata     3720

attaattgca ttttaaattg gcccactttc aaggcaattt tttttgtgtg tctgtaactg     3780

agctcctcca cccctgtcat tcacttccaa ttttacccaa tccaatttta gcactcaagt     3840

tccattgtgt taatttctgc acggtcaaca aacatcaagt cagcaagcat ttgccaccac     3900

tccctatact tctccctcct tcttacacac acacacacac acacacacac aatccatctc     3960

ttgcttgttc ctacctcctg atttttcttc cctacagaaa tagaaatagg gacaaagaag     4020

gggaaaatgt atatattggg gctgggctga acaactaact tcataagtag tattaactag     4080

gggtaaattg agagaaaagc tccttttctc ttcactgttt tggaaaggat agccattagc     4140

atgactgctt tgtgtcctta tggactttag tattagccta gattgaatta tagcgttttc     4200

tagctggaag gaaccttaag atcacatcat ctactcctct actccaaatt tctcattctt     4260

caggccagga aaccgagaca cagaggtaaa gtaatttccc caaggtcaca cagctggctg     4320

gggcaggatt gggtttacaa cccacatctc ctggctctta ttccagggcc ttttcccact     4380

aagtagtatt gccttccatt aggctcctga gagttatttc tcagggtcat gttgcatctt     4440

ggagccacat gctgctgccc tgatctcagt gggaaatcca cccagcaacc taatacagcc     4500

ccttttccct gcattcacct ggttcccatc cacatgggtt gcagatgtcc ttgaagagag     4560

tgaggcattg agggccaata ggagcaatgg ggtccctggc cttgtccatc tgattcagga     4620

gatcactgct ccatcgtgag gagccctctg aatagccccc cactgaatgc ttgccttgcc     4680

caaatggaat ggaggaagat tgattttctc catcagttca ccttgtgtca tctcataatg     4740

gttggtcttt ccaggctgag ggaaatgttt cttgtttcca gagtagaaaa agaaagagtg     4800

gaacaatagc tttgttcatc ctaactttct gagatggctt ttcaacattt taaaaaaact     4860

agtgtggcta ccattcactg gcaatgattt cttttagaat atgggagtaa gatgagctag     4920

agaaaataac ctggtctcac tgtggttgcc ctcatccaca atgtccccaa agccatcctg     4980

ctctgatgag gacaatttcc aggtataagc aaggggcttt gtgacaaaaa tgtaccctgg     5040

ctgatgttaa acattggctc ctgtgtttgc accaaaatag caagctgtgt gctctataca     5100

ctcttcccat cgtcttgtgt acactgctcc tgtggccttc cacagcagaa accagggcaa     5160

aagggtccaa acacatggtt ttccttgctg caaggctctt cctgggaact aagggggtat     5220

ttattagttc agttctaaga gacctccttc tgggcttacc ccactcctca ggtacttctc     5280

tctccttcct ccttctcctc cacagtcaca agtaaccaag gaacctgaaa gtggatgtgt     5340

agctatttga agaaggcaag gaaccctgag attcttcttt gaatcctcta gtccaagtct     5400

tagaccagtg attggtgctt accttgaaca aaattttgtc tgtgttccta atcccttcaa     5460

tactctgggt acaatgctcc caatcaccct gcacatttga ttctaaatgg cttttatttt     5520

ttaaaaatcc atatccctag gacaagagaa caggatgcct atatccccaa aatgagctcc     5580

aggacactga tgggaatgat cccaaagatc accccacctc agaaacgtct gtgccaagag     5640

acttccccag atagaaacac tgggacagtg gtttgaacga cttcttttat ggttgtccag     5700

tttgctatgg aaataaaagg cattgatttt ttaaaaagat gattggaacc tgtctttggc     5760

cacatagggc cacttggatc catttccagg ccttactcat atattgcctt cactgaaggg     5820

ctttggcttt aagtcccaga ctggtctccc aagtgaacca taagtgtttt ggagctcatc     5880

tggggtgagg catgagaatg ttgccccatc tatcccttca ggaaaaggtg ccttccctcc     5940

ctttctccta aagcctggtc cccagaaatt gtttttgtct ccaaaagtct agtatggtct     6000

ttatacaccc agactcttag tgttgcgtcc tgccttgttt ccttgttaag gatctatgca     6060

gacctcccgc tttggcttag ctagcgtgac attggctatc atttgacaag actaactttt     6120

tttttttttt ttttttgact gagtctccct ctgtcaccta ggctggagtg cagtggcaca     6180

atcttggctc gctgcaacct tcacccttca cctcccaggt cgaagcgatt ctcctgcctc     6240

agtctcccga gtagctggga ttacaggcgt gcgccaccaa atctggctat ttttttatta     6300

ttattatttt tagtagagat ggggtttcac catgttggcc agactggtct tgaactcttg     6360

gcctcaaatt atctgcccac ctcggcctcc caaagtgctg ggattacagg catgagccac     6420

catgcccagc tgacaagact aattttttat cccttggttt attggcttca acatcttctg     6480

gaatcagagg tgattttttc ttaccttgga tgcctgagac taggggagta tagaattcca     6540

attggtaatt aaggcatctt tctgctcctg atcagaaggg caggttagtt gggagaggtc     6600

agatggcaca acagaagtca ccttgtaagt aaggcaaaga cttgaaggca ttagcgtttc     6660

tcattactag gtcaataacc tgagggaatc aatggctttt tgccgctcta cctcttgtgt     6720

atctctttga cttttctttc tctgtctagt ttcctctgtt ctcagtttat attctatgtt     6780

atcagtctct ctttccacag tacaaacatc catcctttct cctgtgcaat tctgtctctc     6840

cctcttatta tctttatttg tactttttcc ttcctccctg tctaggcatt gggcatgtgc     6900

ctcttcttag cctgtgattt tgccttggga ctgatgataa attatttcca gattcaatca     6960

gccctggtcc taccccagtc caatcagaag tatgttggtg ggaatcaacc tgatcctggc     7020

cctttcttct tctccatttt cattcgtaat ccccctcagc agatctttac aagcagtttc     7080

cttatagctc atgtatcttt aggtctttgc cttccaagca ctgtacagaa tactttgtgg     7140

ttccttttta gtctgacatt ttgtggagca gtgaagcgtg ctcagagaca taatcagctg     7200

aagagaaaaa atccacccat ggatttatat cagctaaata ctaataattg attttgtttg     7260

atgtgcccat aatttttaaa gctgcaatat aatataatga gggaccacag gtaatttctc     7320

ctgtcatttg ttttggctgg atgggggtgg gggagtaatt gcttaaagtt ttaccattac     7380

acattaaact ctctataata atcttgtttg gggcttgcta actgttgagc tgttttaact     7440

aaactggtag gcaatcggag ttgatttaaa tgaaaagata atttaacaaa tctatactat     7500

aaaaagagac atttgcttaa ttgacatgta ttttttcctt ctgagtcacc taaacattta     7560

ctcttgacac caactgttca tgatactgaa tagacagtcc atataagaga aattagtgga     7620

cctaaagaag ccagattgta ggtgttaatt tattaaacag agtgcaaagc ccttggaaat     7680

gtcactgctt ggcaatacca tatggaatgc caaaatttac aatgactttt ctttataagt     7740

tatccaaaag ggatttgaac aagtaagagg ttatgccaaa atgtctccaa tgtatggtcc     7800

tgtaatatat tgcagcttga agccaatgat cccttatgac ttgtatacaa ctaatgcatg     7860

ttttattgaa ttttgcattt cccacgtgtg gtaagttctt taaaatgttt ttgatcacct     7920

ttttgtgcca ttaaacttgt acagaaaatg tttttatggc cattttcaaa gggagaaagt     7980

ttaaaatgga aacagcccac cctttctgcc ctatagctgt agttagaatt gagtacctgt     8040

agcaaaacag ctgtaattgg tggttgtagt gttagaggtg ttagcttgct agtgactagc     8100

tttggagagt aaatgcatgg tattgtacat cacatttctt aactcgtttt aacctctgaa     8160

aagaatatat tcttctttgt agtccttctt cccaccccct tgccctctcc ctctccctgc     8220

tcccagttgt cttacagttg taaatatctg atttgaggcc caataactct tgccaagtaa     8280

agtcagcaaa caacaaacaa accaaaatgt ggggaaaagg catttctcaa ccatctctca     8340

gcagttattg atcatttctt aaggaacagc attgtgatca aagactcaac tttacgtaaa     8400

aatcagtggt aaattggggt tgtatttggc catttgatta catttcagga ttgaatagtt     8460

ttcagaatca catgtaatcc aaagacagta ggtagtgatg tcccttatcc ctgcagctgt     8520

tttaagatag agacctcaga agactctgct tgaccgatga ccaataatta tttgaaaaaa     8580

aaagaaaaaa tgagagaaat aaaacagata tttaagaact ttagccacct atttagaata     8640

gttatagcca gaaaaaaaaa caagggcatg agttcaaatg cattactatc agtgtcctag     8700

gcaataccta acctactctg aaattgtgat tcaaaagcag tatttcaaga ggcattctcc     8760

ttttttggtt tgctgacccc acttggactg gtaggtttgg tgaggccccc ataaaccagc     8820

tggagcagac ccttttcatc tcctgtgcct gtaacacccc tcttccccca ccccctccgc     8880

aattcaatga gggctttctt gggtcagagg acttcaaggt tgtctagaga agtttgccat     8940

gtgtgtaagg tgctgtgaac tgtgagtgct gaagattcgc agcattcaat accaggcagc     9000

caaagagctg ctcttgcaat tattttggct ctcaagctct gttcttcatc gcattctcat     9060

ttctgtgtac atttgcaaga tgtgtgtaat gtcattttcc aaaaataaaa tttgatttca     9120

ataaaaaaaa aaaaaaaaaa aaaaaaaaaa                                      9150


<210>  1344
<211>  3594
<212>  DNA
<213>  homo sapiens

<400>  1344
ctttcttctc tctctgtttc tctcttgtgt ctttttgtcc ttatcttggt ctctctgctt       60

ctatttctac ctctctcagc gtgtgcgtct ctctttccct gtatgtctct gtctttctcc      120

gagtctctct tcttctcccc gcccccctca ctcccctttc tccgtccctc tctgtctctg      180

cgcctttctc gccctcactt tctcccctcc tgcctgctcc gggcctgccc ccaccgccgc      240

cggttcaggg gaacgtgtgc ggagcgattg tcctggggga catttgatgg attagagcgc      300

cgagcggttc cattgctagg ggaccacctg atctccagcc tgcgtcccat ataaagccgg      360

cagccggagt gctgagcgca gctcccgcga tcccctgtct gcgcgccgcc gccgccaagc      420

ccgagcccga gccggggccg ccgccaccgg tgccggctcc gagcggcctc ccgcgctcca      480

gcccgctggg agctgtccag tgctgaaaac ccgcgcggac acagccgatc gcgcccggcc      540

ggccgcctcc ccgcaccgag ccccgcgccg gccgcgccat gccgcgctcc ttcctggtaa      600

agaagatcaa aggggacggc ttccagtgca gcggggtgcc ggcccccacc taccacccct      660

tggagacagc ctacgtgctg cctggcgccc gggggcctcc cggggacaac gggtacgccc      720

cgcaccgcct gcccccgagc agctacgatg cggaccagaa gccgggcctg gagctggccc      780

cggccgagcc cgcgtacccg ccggcggcgc cggaggagta cagcgacccc gaaagcccgc      840

agtcgagcct gtcggcgcgc tacttccgag gggaggcggc agtgaccgac agctactcca      900

tggacgcctt cttcatctcg gacgggcgct cgcggcggcg gcggggcggg ggcggcgggg      960

acgcgggggg ctcgggagac gcggggggcg ccggggggcg cgcggggcgc gcgggggcgc     1020

aggcgggcgg cgggcaccgg cacgcgtgcg ccgagtgcgg caagacctac gccacgtcgt     1080

cgaacctgag ccgccacaag cagacgcacc gcagcctgga cagccagctg gcgcgcaaat     1140

gcccgacgtg cggcaaggcc tacgtgtcca tgcccgcgct cgccatgcac ctgctcacgc     1200

acaacctgcg ccacaagtgc ggcgtctgcg gcaaggcctt ctcgcggccc tggctgctgc     1260

agggtcacat gcgctcgcac accggcgaaa agccgttcgg ctgcgcgcac tgcggcaagg     1320

ccttcgccga ccgctccaac ctgcgcgcgc acatgcagac gcactcggcc ttcaagcact     1380

accgctgccg ccagtgcgac aagagcttcg cgctcaagtc ctacctccac aagcactgcg     1440

aggcggcctg cgccaaggcg gccgagccac ccccgccgac ccccgccggc ccggccagct     1500

gagccttccg cctcgccctc gcgcccggaa ctcgctctcc acgcgccccg ggccccctac     1560

ctgcgcccgc agcgccctcg cccagccccg gctgcgtttc cctgcccatg accctctcgt     1620

ggggaccccc ggcccggccc ggaacttttc tccccaaccc ccaaacccac gactcacttc     1680

cacaccgtct tccccagcgt cccccgaccc acttcatcct ttccggccat ccctcggacc     1740

ttgacccccc tgtccgcgcc ttcaaggctc ccaactcagg caccaggtcc gcacctctcc     1800

cgcgccccag agccggaaat ttctccctcc cagaccccgc gctgctcttc taacttctag     1860

atcttttctc tcgcttctca gctgaatctc tctgaccatt cctctactgg agcccccaat     1920

gaaagccgca aacctatacc cttgacgccc atacctgcct cagtttcccc atccacacct     1980

ggacgcaggc cctgccgccc tgagaccaca gtccaacccc agaccatccc tctggcctct     2040

gctgaatctc ccagagtgtg tccatctggg gatctaatct tcacccttct tgaagtctcc     2100

gatctgtccc tgatcccatc catgctcagg ccttaggtct ggccattcac acacacacac     2160

acccccacac cccactccca cacacagttc ctactgtctt cagtccatgg ggatctcatc     2220

acccactccc agccccagct ccagctgccc tcacctctct agcagctctc acccctctga     2280

gtctacctaa cctggagggg gcttgagggg cacttcaggg ccctgccccc taatgtaacc     2340

cctctctcac cccggcacaa cctgggcttc cacagtctgg agctgcccta cccccagatt     2400

ctctgagcac tttcccccat ccccagggcc acagatcccc ttccttactt gttgggggga     2460

ggtctggagc acctcgccaa tgcccttccc ccatccggct gggtccttcc agttatttat     2520

ttgtgtattt atttatttat ctatttatta ttctatttaa tctcttggcc tcacccaggg     2580

accgtctggc ttccccagct ggactgggag gtcaggaagc caggcaagga gagggacagc     2640

acaggccaca gagggctgcc cccaccacac acacccccgc gtctcgggag aaacccaccc     2700

tcttcagagc ctgcactcgc taaggaaggg gactcgagaa tgggggggca gcttgctgac     2760

cctcaactgg gggggtgagg gagcatcagg aggtccaggc gtggggcagg tccccacctt     2820

cctgaacctt cccctgccac tccaggcggc ccggagagag gagcctcttc gatttgtttc     2880

ctgtttattc ttcttcccga gggaccccag gttccaggga ccgactgagc cccggacccg     2940

ctggggcctc tggcctgctc cccgggaggg gcgctctctc ccggccatgt ctatgcaact     3000

ctcccggaca gaggggccgg gctgccagcc acccgcccgt tggccgccac tacctcctcc     3060

gctgcgcttt tgcatgcccg ggcgaggacc gaagcacaca cctccacgcg cacgggccct     3120

ggccccctcc gctttaagca cacgcctctg ccccattgct ctgcagccag cttgggggca     3180

ggagtcctgg actctcagat cctcctctcc cctcctctta gccacaaaag aggggggaga     3240

ctggaggcac ccctgcagca ggggcacttc cctagggctc cagaggggtg aatgggcctt     3300

tgctcagctc caggcccagc gggaagggag gctgcaggga tggtgggagg gagaggggta     3360

gcagaagcaa ttatggaggc gttgaccctg taaatagcaa cttctgacag caataatttt     3420

ccatgcatgc taagcctttt ggccatattt tgtatgagcg cttggcgctc ctcctccgtc     3480

ctatcccaac tcacccccaa acccccatcc cttccccacc tccagcagta ttacttgtaa     3540

cgcaattcag ggatattaaa gggactttgg ccactcaaaa aaaaaaaaaa aaaa           3594


<210>  1345
<211>  2075
<212>  DNA
<213>  homo sapiens

<400>  1345
cggccccccg cattccccgc ccccacctcc ccgccttgtt gtccaacttc tcccggagca       60

gccggagagc aggcgtcggg acgcagcaaa gagaggagag gccaccatgg cggagctgca      120

ggaggtgcag atcacagagg agaagccact gttgccagga cagacgcctg aggcggccaa      180

ggaggctgag ttagctgccc gaatcctcct ggaccaggga cagactcact ctgtggagac      240

accatacggc tctgtcactt tcactgtcta tggcaccccc aaacccaaac gcccagcgat      300

ccttacctac cacgatgtgg gactcaacta taaatcttgc ttccagccac tgtttcagtt      360

cgaggacatg caggaaatca ttcagaactt tgtgcgggtt catgtggatg cccctggaat      420

ggaagaggga gcccctgtgt tccctttggg atatcagtac ccatctctgg accagcttgc      480

agacatgatc ccttgcgtcc tgcagtacct aaatttctct acaataattg gagttggtgt      540

tggagctgga gcctacatcc tggcgagata tgctcttaac cacccggaca ctgttgaagg      600

tcttgtcctc atcaacattg atcccaatgc caagggttgg atggattggg cagcccacaa      660

gctaacaggc ctcacctctt ccattccgga gatgatcctt ggacatcttt tcagccagga      720

agagctctct ggaaattctg agttgataca aaagtacaga aatatcatta cacatgcacc      780

caacctggat aacattgaat tgtactggaa cagctacaac aaccgccgag acctgaactt      840

tgagcgtgga ggtgatatca ccctcaggtg tcctgtgatg ctggtggtag gagaccaagc      900

acctcatgaa gatgcagtgg tggaatgtaa ctcaaaactg gaccccaccc agacctcgtt      960

cctcaagatg gctgactccg gaggtcagcc ccagctgact cagccaggca agctgaccga     1020

ggccttcaag tacttcctgc aaggcatggg ctacatggcc tcatcctgca tgactcgcct     1080

gtcccggtct cgtacagcct ctctgaccag tgcagcatcc gttgatggca accggtcccg     1140

ctctcgcacc ctgtcccaga gcagcgagtc tggaactctt tcttcggggc ccccggggca     1200

caccatggag gtctcctgtt gaatggccct tgttgcccta gagtgggacc cagccctcac     1260

ctcccccaga gctaacctgg gaggtgctga aggggcattg ggccaccgta agcaagggaa     1320

aaagggcaga tcatgcgggg agatgacctt gatctttgat tgctacccta accttgacct     1380

ttaacccgtg attcccccca gctcctggaa gagatgtcct aatatctctt agggacccag     1440

acccctaaat tctcctcctc ccccattttg atgttaaggt ggagagggca tatgcatcct     1500

ctgtcctgat ctaggtgtct atagctgagg ggtaagaggt tgttgtagtt gtcctggtgc     1560

ctccatcaga ctctccctac ttgtcccata tttgcaaggg gaggggattt ggggctgggg     1620

ctccattcac caaagctgag gtggcttctc attaaccctt taggactctg aagggtatgg     1680

acctacgtga atgtgtgtca gggggagact tgctggtggg ttagtggtcc tcaggatgtg     1740

atagaaacat ccagtgtaaa aaggaagttg gaatgggagt tggcgggcag tgaacgagtg     1800

tggggaagga ttggtgctgg ggcaacagga aggggcctgg ggccgtttgg ctgcactaac     1860

tttggtagct cagtgtgcat ctagagtggg actggggagg gagctaagct tgggctgggc     1920

tgcttggggc ttggcatagg gtggaaaggg ctaccctggg gctctgacca cactgtagta     1980

tgtgtggagg gtgccctccc gtctcccaca acttctgcta taacaataaa ctgtagagga     2040

atctgagtac cgttaaaaaa aaaaaaaaaa aaaaa                                2075


<210>  1346
<211>  3779
<212>  DNA
<213>  homo sapiens

<400>  1346
ctctttaagg tgcccgaggc tcgcgggcgc tgcgctgagg ggacggcggg aggcgcggcc       60

tggcctcgca ctcaaagccg ccgcagcgcg ccccgggctc ggccgacccg gcggggatct      120

aggggtgggc gacttcgcgg gaccgtggcg catgtttcct gggagttact gatcatcttc      180

tttgaagaaa catgaagtta cactatgttg ctgtgcttac tctagccatc ctgatgttcc      240

tgacatggct tccagaatca ctgagctgta acaaagcact ctgtgctagt gatgtgagca      300

aatgcctcat tcaggagctc tgccagtgcc ggccgggaga aggcaattgc tcctgctgta      360

aggagtgcat gctgtgtctt ggggcccttt gggacgagtg ctgtgactgt gttggtatgt      420

gtaatcctcg aaattatagt gacacacctc caacttcaaa gagcacagtg gaggagctgc      480

atgaaccgat cccttctctc ttccgggcac tcacagaagg agatactcag ttgaattgga      540

acatcgtttc tttccctgtt gcagaagaac tttcacatca tgagaatctg gtttcatttt      600

tagaaactgt gaaccagcca caccaccaga atgtgtctgt ccccagcaat aatgttcacg      660

cgccttattc cagtgacaaa gaacacatgt gtactgtggt ttattttgat gactgcatgt      720

ccatacatca gtgtaaaata tcctgtgagt ccatgggagc atccaaatat cgctggtttc      780

ataatgcctg ctgcgagtgc attggtccag aatgtattga ctatggtagt aaaactgtca      840

aatgtatgaa ctgcatgttt taaagaagac aaatgcaaac caaagcaact tagtaaaata      900

ataggtataa aaagttattc tgtaagtctg ttggttgtat cttgtatcag aatcccagta      960

agttaagttg taaagacttt ggaataagtt tcttttaaaa atatgacata gccagtgatg     1020

tgtttaatta tataactgtt cttactgatt ttattgcccc ctagcaataa gccctttcct     1080

ttgaatacat gtacaacttt ggtcatatga gaagcaggtg cgcagagaat tccttgaaag     1140

atctgaggtt tttaacatga agtctgatgt ggttttcctc tagcattcca aaaggttttt     1200

gctttgaaag tgttagcaga agcatgttga tgtgaattat gatttcttca tgtgctactg     1260

ttagcacact gagtttttat agttgcacat cattcctcat tgtgccttgt tttatccatt     1320

ttataaatag agtagatatt tgatatacca ctctgataac tcatataaaa atatcatcat     1380

aaaaagctta atttcatccc ttttatgttg gttttaaaag gtaaatgctt accatatttt     1440

ataattgaga actcttacat agtagaatcc attctataat acatgtgttg acaaagcttt     1500

agagaaagtt tcctattctc ttccatttcc cctgcccaaa gtgctgacat aggcagtgat     1560

gaagaatctt taccaagatt ttcagggtgt acctatgaaa ttgctttaaa tgcactgctg     1620

gtgtaaataa ttagcaagca aaagcgtttc tgtgacttca ggtaccagct taaagagcac     1680

tagggatggg gaacgaatgc caaatcagac tccacctaga gcaccaggaa acagcttgta     1740

ccctggtagg gaaatggtgt tgctgaaagg ggaggctgag ccagtgcgag actgaacttg     1800

tgcagcctta gccaagacaa agcagtgttt ttcagcagac ggctgatggg acaggaattg     1860

aagaagagaa ttgactcgta tgaacaggac agggtgaaaa tgctgggaat tataatggga     1920

aacaaaacta tctatgttca tattttgtaa tatttcattt gttaagttta tatctggata     1980

taatgttctt tttaaacaag tataatcata tcgtcggagg ttaagattat gaaattttag     2040

aatctctatt caagatgatg ttcactccaa atacactaca gaatttagtc aacattttat     2100

ataatgtttc aataaatgtt tctttcaata aagatactat gtgcccttca tagtaataaa     2160

atctcaatct taaagcatga atctaaaaca taaatattta tattacagac tcaattttac     2220

aaaattacta attgctctag tgcatatttg aactacaagc aactttttag gaatacctct     2280

ttatacgtct acatatttta gtatataaaa atagataatg ctcttggaca cattttgtat     2340

tattcatgat ctgaatagta gttagttaaa agatcatttg taatattatg atcaactgtt     2400

ataaattaag gtcttaatac cttttctgct ctttcaaata actctaatga atattcaaga     2460

tattttagcc ttttaaaaag ttgagattta gctcatggat atattttttg gtagggaaac     2520

attagggtct ccttttcttc cttttaccta gaatgcctca tttaaaagtg ccttgaaaac     2580

atttagctcc ccttcttcat gagcatctgt agagctgaaa gtattctgga actttagaca     2640

gaaagctgaa aggaatctgc agtctcctgc tgcagttcaa ctctgctgtt tttcagtcat     2700

ttcctactgt gagtggagtg atgtttgtgt gtgtgttggc aacatgccta atgttttctt     2760

aatgatgaca acaaatattt taaaactgca tttatcattt tttaggtctt cattaaattt     2820

taaaatgtaa tatctgtttc ccacccccta cattaggagg ataatttctt aaaccacatt     2880

gttttaattg atttttctta tcttgatttc tttcattaga aactatccct aaatgtaaag     2940

atcttttgcc ttcaaatttg gcttattttt tctgatttat gagggtttga aagaaagaat     3000

tcacctaaaa gattccattt ccagttttat aatgtatttc aggttctgaa taacaatatt     3060

tttccaaatt gaaagtaaat attcaagaag ttgatagcct ggttaaaagt tagatcctct     3120

attaccattc taagcacatt cacttctata ttgaagtttt ggtaaaaatt cttttttctt     3180

ttttaataaa aaattaggtt attacttttt ttataaccag atttttaaag cactaggttt     3240

taaatcagtg ggtatcataa aagccatata taaaagatcc tttcttatag taagacttgt     3300

gcttgttagc aggtttttct gttagttttt cccccataac atttaattat tactaaaatt     3360

gtatttacaa tagtggtgcc aaatcaaatg gtaatttaaa taaaatctat tctgtgttta     3420

tgtagggtgg tataaaaaag aggtcttcat ttagacatgt gatttctaaa attccagaaa     3480

gcaaaattga taagatgtta gaaatttgga ccgttattta taatcagggt agcattaaaa     3540

tggagaaaag aaagttttct gaaaaaatgc agtaaatata agccacattt ctaaagttta     3600

tttttatgaa agcttctttt aagattttga aatctattct gcattcccaa gagtttatgt     3660

ttattgtatt ttatatgatc tacaacatat aaaattgtgt atttttcttt ggttgtccct     3720

attaacaaaa aagtatttta ataaaaaatt gaaatgaaaa aaaaaaaaaa aaaaaaaaa      3779


<210>  1347
<211>  2679
<212>  DNA
<213>  homo sapiens

<400>  1347
agagccagcg gacggaacca ttccaaacag cctagtctcg tgctgagagc ctctccggtt       60

tcacgctgag acccgctcac ccccgctctg gccccttaga tgctattttg gcccgagtgt      120

cacgtcgggc gctctttaga gaggactggg acaagagttg cggacgcgaa gaacgagtaa      180

gcggtggttc atccctcctg accccacccc cgtggcctgg cccgatggtc gcgcccgggg      240

ttgcgagatt tgcgcctgcg cagtgcggcg cctagaggga aagcgagagg gagacggacg      300

ttgagagaac gaggaggaag gagagaaaat ggcgtccacg gattacagta cctatagcca      360

agctgcagcg cagcagggct acagtgctta caccgcccag cccactcaag gatatgcaca      420

gaccacccag gcatatgggc aacaaagcta tggaacctat ggacagccca ctgatgtcag      480

ctatacccag gctcagacca ctgcaaccta tgggcagacc gcctatgcaa cttcttatgg      540

acagcctccc actggttata ctactccaac tgccccccag gcatacagcc agcctgtcca      600

ggggtatggc actggtgctt atgataccac cactgctaca gtcaccacca cccaggcctc      660

ctatgcagct cagtctgcat atggcactca gcctgcttat ccagcctatg ggcagcagcc      720

agcagccact gcacctacaa gaccgcagga tggaaacaag cccactgaga ctagtcaacc      780

tcaatctagc acagggggtt acaaccagcc cagcctagga tatggacaga gtaactacag      840

ttatccccag gtacctggga gctaccccat gcagccagtc actgcacctc catcctaccc      900

tcctaccagc tattcctcta cacagccgac tagttatgat cagagcagtt actctcagca      960

gaacacctat gggcaaccga gcagctatgg acagcagagt agctatggtc aacaaagcag     1020

ctatgggcag cagcctccca ctagttaccc accccaaact ggatcctaca gccaagctcc     1080

aagtcaatat agccaacaga gcagcagcta cgggcagcag agttcattcc gacaggacca     1140

ccccagtagc atgggtgttt atgggcagga gtctggagga ttttccggac caggagagaa     1200

ccggagcatg agtggccctg ataaccgggg caggggaaga gggggatttg atcgtggagg     1260

catgagcaga ggtgggcggg gaggaggacg cggtggaatg ggcagcgctg gagagcgagg     1320

tggcttcaat aagcctggtg gacccatgga tgaaggacca gatcttgatc taggcccacc     1380

tgtagatcca gatgaagact ctgacaacag tgcaatttat gtacaaggat taaatgacag     1440

tgtgactcta gatgatctgg cagacttctt taagcagtgt ggggttgtta agatgaacaa     1500

gagaactggg caacccatga tccacatcta cctggacaag gaaacaggaa agcccaaagg     1560

cgatgccaca gtgtcctatg aagacccacc cactgccaag gctgccgtgg aatggtttga     1620

tgggaaagat tttcaaggga gcaaacttaa agtctccctt gctcggaaga agcctccaat     1680

gaacagtatg cggggtggtc tgccaccccg tgagggcaga ggcatgccac caccactccg     1740

tggaggtcca ggaggcccag gaggtcctgg gggacccatg ggtcgcatgg gaggccgtgg     1800

aggagataga ggaggcttcc ctccaagagg accccggggt tcccgaggga acccctctgg     1860

aggaggaaac gtccagcacc gagctggaga ctggcagtgt cccaatccgg gttgtggaaa     1920

ccagaacttc gcctggagaa cagagtgcaa ccagtgtaag gccccaaagc ctgaaggctt     1980

cctcccgcca ccctttccgc ccccgggtgg tgatcgtggc agaggtggcc ctggtggcat     2040

gcggggagga agaggtggcc tcatggatcg tggtggtccc ggtggaatgt tcagaggtgg     2100

ccgtggtgga gacagaggtg gcttccgtgg tggccggggc atggaccgag gtggctttgg     2160

tggaggaaga cgaggtggcc ctggggggcc ccctggacct ttgatggaac agatgggagg     2220

aagaagagga ggacgtggag gacctggaaa aatggataaa ggcgagcacc gtcaggagcg     2280

cagagatcgg ccctactaga tgcagagacc ccgcagagct gcattgacta ccagatttat     2340

tttttaaacc agaaaatgtt ttaaatttat aattccatat ttataatgtt ggccacaaca     2400

ttatgattat tccttgtctg tactttagta tttttcacca tttgtgaaga aacattaaaa     2460

caagttaaat ggtagtgtgc ggagtttttt tttcttcctt cttttaaaaa tggttgttta     2520

agactttaac aatgggaacc ccttgtgagc atgctcagta tcattgtgga gaaccaagag     2580

ggcctcttaa ctgtaacaat gttcatggtt gtgatgtttt tttttttttt ttaaataaaa     2640

ttccaaatgt ttataaagag tcaaaaaaaa aaaaaaaaa                            2679


<210>  1348
<211>  2694
<212>  DNA
<213>  homo sapiens

<400>  1348
agagccagcg gacggaacca ttccaaacag cctagtctcg tgctgagagc ctctccggtt       60

tcacgctgag acccgctcac ccccgctctg gccccttaga tgctattttg gcccgagtgt      120

cacgtcgggc gctctttaga gaggactggg acaagagttg cggacgcgaa gaacgagtaa      180

gcggtggttc atccctcctg accccacccc cgtggcctgg cccgatggtc gcgcccgggg      240

ttgcgagatt tgcgcctgcg cagtgcggcg cctagaggga aagcgagagg gagacggacg      300

ttgagagaac gaggaggaag gagagaaaat ggcgtccacg gattacagta cctatagcca      360

agctgcagcg cagcagggct acagtgctta caccgcccag cccactcaag gatatgcaca      420

gaccacccag gcatatgggc aacaaagcta tggaacctat ggacagccca ctgatgtcag      480

ctatacccag gctcagacca ctgcaaccta tgggcagacc gcctatgcaa cttcttatgg      540

acagcctccc actgtagaag ggaccagtac aggttatact actccaactg ccccccaggc      600

atacagccag cctgtccagg ggtatggcac tggtgcttat gataccacca ctgctacagt      660

caccaccacc caggcctcct atgcagctca gtctgcatat ggcactcagc ctgcttatcc      720

agcctatggg cagcagccag cagccactgc acctacaaga ccgcaggatg gaaacaagcc      780

cactgagact agtcaacctc aatctagcac agggggttac aaccagccca gcctaggata      840

tggacagagt aactacagtt atccccaggt acctgggagc taccccatgc agccagtcac      900

tgcacctcca tcctaccctc ctaccagcta ttcctctaca cagccgacta gttatgatca      960

gagcagttac tctcagcaga acacctatgg gcaaccgagc agctatggac agcagagtag     1020

ctatggtcaa caaagcagct atgggcagca gcctcccact agttacccac cccaaactgg     1080

atcctacagc caagctccaa gtcaatatag ccaacagagc agcagctacg ggcagcagag     1140

ttcattccga caggaccacc ccagtagcat gggtgtttat gggcaggagt ctggaggatt     1200

ttccggacca ggagagaacc ggagcatgag tggccctgat aaccggggca ggggaagagg     1260

gggatttgat cgtggaggca tgagcagagg tgggcgggga ggaggacgcg gtggaatggg     1320

cgctggagag cgaggtggct tcaataagcc tggtggaccc atggatgaag gaccagatct     1380

tgatctaggc ccacctgtag atccagatga agactctgac aacagtgcaa tttatgtaca     1440

aggattaaat gacagtgtga ctctagatga tctggcagac ttctttaagc agtgtggggt     1500

tgttaagatg aacaagagaa ctgggcaacc catgatccac atctacctgg acaaggaaac     1560

aggaaagccc aaaggcgatg ccacagtgtc ctatgaagac ccacccactg ccaaggctgc     1620

cgtggaatgg tttgatggga aagattttca agggagcaaa cttaaagtct cccttgctcg     1680

gaagaagcct ccaatgaaca gtatgcgggg tggtctgcca ccccgtgagg gcagaggcat     1740

gccaccacca ctccgtggag gtccaggagg cccaggaggt cctgggggac ccatgggtcg     1800

catgggaggc cgtggaggag atagaggagg cttccctcca agaggacccc ggggttcccg     1860

agggaacccc tctggaggag gaaacgtcca gcaccgagct ggagactggc agtgtcccaa     1920

tccgggttgt ggaaaccaga acttcgcctg gagaacagag tgcaaccagt gtaaggcccc     1980

aaagcctgaa ggcttcctcc cgccaccctt tccgcccccg ggtggtgatc gtggcagagg     2040

tggccctggt ggcatgcggg gaggaagagg tggcctcatg gatcgtggtg gtcccggtgg     2100

aatgttcaga ggtggccgtg gtggagacag aggtggcttc cgtggtggcc ggggcatgga     2160

ccgaggtggc tttggtggag gaagacgagg tggccctggg gggccccctg gacctttgat     2220

ggaacagatg ggaggaagaa gaggaggacg tggaggacct ggaaaaatgg ataaaggcga     2280

gcaccgtcag gagcgcagag atcggcccta ctagatgcag agaccccgca gagctgcatt     2340

gactaccaga tttatttttt aaaccagaaa atgttttaaa tttataattc catatttata     2400

atgttggcca caacattatg attattcctt gtctgtactt tagtattttt caccatttgt     2460

gaagaaacat taaaacaagt taaatggtag tgtgcggagt ttttttttct tccttctttt     2520

aaaaatggtt gtttaagact ttaacaatgg gaaccccttg tgagcatgct cagtatcatt     2580

gtggagaacc aagagggcct cttaactgta acaatgttca tggttgtgat gttttttttt     2640

tttttttaaa taaaattcca aatgtttata aagagtcaaa aaaaaaaaaa aaaa           2694


<210>  1349
<211>  2702
<212>  DNA
<213>  homo sapiens

<400>  1349
gcgcgctctg ctcggctgca ggctcaggaa gcggcgcggc ggcacgtgct gggccagagc       60

cccgcgccct gcgtccagcc gccgggtgtg tgcgcccgcg tagcccagcg tcgcgcctcg      120

gcgcccccac gcgcccacgc agcggcgcgg ggacccgggc gggggcagag ggagggcccg      180

gcccagggag gagaaggggc cggtcctccc ggcgcaggca gcagccgcgg cagcccagga      240

ggcggaggca gcggcaacgg cagagacagc aacgtgcccg ccgcagtcag cccggcctcg      300

tcggacccgc accggcccgc ccgcccgccc gcaccgcgtc ggggcgccct ctccactgcg      360

cgcggtacaa ggaaatggta gaactagtga tctcacccag cctcactgta aacagcgatt      420

gtctggataa actgaagttt aaccgtgctg acgctgctgt gtggactctg agtgacagac      480

aaggcatcac caaatcggcc cccctgagag tgtcccagct cttctccaga tcttgcccac      540

gtgtcctccc ccgccagcct tccacagcca tggcagccta cggccagacg cagtacagtg      600

cggggatcca gcaggctacc ccctatacag cttacccacc tccagcacaa gcctatggaa      660

tcccttccta cagcatcaag acagaagaca gcttgaacca ttcccctggc cagagtggat      720

tcctcagcta tggctccagc ttcagcacct cacccactgg acagagccca tacacctacc      780

agatgcacgg cacaacaggg ttctatcaag gaggaaatgg actgggcaac gcagccggtt      840

tcgggagtgt gcaccaggac tatccttcct accccggctt cccccagagc cagtaccccc      900

agtattacgg ctcatcctac aaccctccct acgtcccggc cagcagcatc tgcccttcgc      960

ccctctccac gtccacctac gtcctccagg aggcatctca caacgtcccc aaccagagtt     1020

ccgagtcact tgctggtgaa tacaacacac acaatggacc ttccacacca gcgaaagagg     1080

gagacacaga caggccgcac cgggcctccg acgggaagct ccgaggccgg tctaagagga     1140

gcagtgaccc gtccccggca ggggacaatg agattgagcg tgtgttcgtg tgggacttgg     1200

atgagacaat aattattttt cactccttac tcacggggac atttgcatcc agatacggga     1260

aggacaccac gacgtccgtg cgcattggcc ttatgatgga agagatgatc ttcaaccttg     1320

cagatacaca tctgttcttc aatgacctgg aggattgtga ccagatccac gttgatgacg     1380

tctcatcaga tgacaatggc caagatttaa gcacatacaa cttctccgct gacggcttcc     1440

acagttcggc cccaggagcc aacctgtgcc tgggctctgg cgtgcacggc ggcgtggact     1500

ggatgaggaa gctggccttc cgctaccggc gggtgaagga gatgtacaat acctacaaga     1560

acaacgttgg tgggttgata ggcactccca aaagggagac ctggctacag ctccgagctg     1620

agctggaagc tctcacagac ctctggctga cccactccct gaaggcacta aacctcatca     1680

actcccggcc caactgtgtc aatgtgctgg tcaccaccac tcaactaatt cctgccctgg     1740

ccaaagtcct gctatatggc ctggggtctg tgtttcctat tgagaacatc tacagtgcaa     1800

ccaagacagg gaaggagagc tgcttcgaga ggataatgca gagattcggc agaaaagctg     1860

tctacgtggt gatcggtgat ggtgtggaag aggagcaagg agcgaaaaag cacaacatgc     1920

ctttctggcg gatatcctgc cacgcagacc tggaggcact gaggcacgcc ctggagctgg     1980

agtatttata gcaggatcag cagcatctcc acctgccatc tcaccctcag accccctcgc     2040

cttccccacc tccccaccga gaactccaga gacccagatg ttggacacca ggaaggggcc     2100

ccacagccga gacgacgtgt ccagtgacca tctcagaagc cgtccatcag tccaaatggg     2160

ggttctgaga aggaaagtac ccaacattgg cttcggagta tttgactttg gggaaaaggg     2220

ctggctcgga gtctagactc ttctgtaaga ctcacagaac aaaagcaagg aattgctgat     2280

ttggggggtg cctggtgatg aggaggggat gggtttgtct tgtcttcttt ttaatttatg     2340

gactagtctc attactccgg aattatgctc ttgtacctgt gtggctgggt ttcttagtcg     2400

ttggtttggt ttggtttttt gaactggtat gtggggtggt tcacagttct aatgtaagca     2460

ctctattctc caagttgtgc tttgtgggga caatcattct ttgaacatta gagaggaagg     2520

cagttcaagc tgttgaaaag actattgctt atttttgttt ttaaagacct acttgacgtc     2580

atgtggacag tgcacgtgcc ttacgctaca tcttgttttc taggaagagg gggatgctgg     2640

gaaggaatgg gtgctttgtg atggataaaa ggcattaaat aaaaccacgt ttacattttg     2700

aa                                                                    2702


<210>  1350
<211>  2483
<212>  DNA
<213>  homo sapiens

<400>  1350
gcgcgctctg ctcggctgca ggctcaggaa gcggcgcggc ggcacgtgct gggccagagc       60

cccgcgccct gcgtccagcc gccgggtgtg tgcgcccgcg tagcccagcg tcgcgcctcg      120

gcgcccccac gcgcccacgc agcggcgcgg ggacccgggc gggggcagag ggagggcccg      180

gcccagggag gagaaggggc cggtcctccc ggcgcaggca gcagccgcgg cagcccagga      240

ggcggaggca gcggcaacgg cagagacagc aacgtgcccg ccgcagtcag cccggcctcg      300

tcggacccgc accggcccgc ccgcccgccc gcaccgcgtc ggggcgccct ctccactgcg      360

cgcggtacaa ggaaatggta gaactagtga tctcacccag cctcactgta aacagcgatt      420

gtctggataa actgaagttt aaccgtgctg acgctgctgt gtggactctg agtgacagac      480

aaggcatcac caaatcggcc cccctgagag tgtcccagct cttctccaga tcttgcccac      540

gtgtcctccc ccgccagcct tccacagcca tggcagccta cggccagacg cagtacagtg      600

cggggatcca gcaggctacc ccctatacag cttacccacc tccagcacaa gcctatggaa      660

tcccttccta cagcatcaag acagaagaca gcttgaacca ttcccctggc cagagtggat      720

tcctcagcta tggctccagc ttcagcacct cacccactgg acagagccca tacacctacc      780

agatgcacgg cacaacaggg ttctatcaag gaggaaatgg actgggcaac gcagccggtt      840

tcgggagtgt gcaccaggac tatccttcct accccggctt cccccagagc cagtaccccc      900

agtattacgg ctcatcctac aaccctccct acgtcccggc cagcagcatc tgcccttcgc      960

ccctctccac gtccacctac gtcctccagg aggcatctca caacgtcccc aaccagagtt     1020

ccgagtcact tgctggtgaa tacaacacac acaatggacc ttccacacca gcgaaagagg     1080

gagacacaga caggccgcac cgggcctccg acgggaagct ccgaggccgg tctaagagga     1140

gcagtgaccc gtccccggca ggggacaatg agattgagcg tgtgttcgtg tgggacttgg     1200

atgagacaat aattattttt cactccttac tcacggggac atttgcatcc agatacggga     1260

aggacaccac gacgtccgtg cgcattggcc ttatgatgga agagatgatc ttcaaccttg     1320

cagatacaca tctgttcttc aatgacctgg aggattgtga ccagatccac gttgatgacg     1380

tctcatcaga tgacaatggc caagatttaa gcacatacaa cttctccgct gacggcttcc     1440

acagttcggc cccaggagcc aacctgtgcc tgggctctgg cgtgcacggc ggcgtggact     1500

ggatgaggaa gctggccttc cgctaccggc gggtgaagga gatgtacaat acctacaaga     1560

acaacgttgg tgggaaggag agctgcttcg agaggataat gcagagattc ggcagaaaag     1620

ctgtctacgt ggtgatcggt gatggtgtgg aagaggagca aggagcgaaa aagcacaaca     1680

tgcctttctg gcggatatcc tgccacgcag acctggaggc actgaggcac gccctggagc     1740

tggagtattt atagcaggat cagcagcatc tccacctgcc atctcaccct cagaccccct     1800

cgccttcccc acctccccac cgagaactcc agagacccag atgttggaca ccaggaaggg     1860

gccccacagc cgagacgacg tgtccagtga ccatctcaga agccgtccat cagtccaaat     1920

gggggttctg agaaggaaag tacccaacat tggcttcgga gtatttgact ttggggaaaa     1980

gggctggctc ggagtctaga ctcttctgta agactcacag aacaaaagca aggaattgct     2040

gatttggggg gtgcctggtg atgaggaggg gatgggtttg tcttgtcttc tttttaattt     2100

atggactagt ctcattactc cggaattatg ctcttgtacc tgtgtggctg ggtttcttag     2160

tcgttggttt ggtttggttt tttgaactgg tatgtggggt ggttcacagt tctaatgtaa     2220

gcactctatt ctccaagttg tgctttgtgg ggacaatcat tctttgaaca ttagagagga     2280

aggcagttca agctgttgaa aagactattg cttatttttg tttttaaaga cctacttgac     2340

gtcatgtgga cagtgcacgt gccttacgct acatcttgtt ttctaggaag agggggatgc     2400

tgggaaggaa tgggtgcttt gtgatggata aaaggcatta aataaaacca cgtttacatt     2460

ttgaaaaaaa aaaaaaaaaa aaa                                             2483


<210>  1351
<211>  3070
<212>  DNA
<213>  homo sapiens

<400>  1351
aaaccccgac cgccggcctg gcgcgcggct gcgcccaccg gctccgcgct gctgccgccg       60

ccaccgccac cccgccgccg ccccggcccg cgggccgccc aggctagtac ccgggccggc      120

ctgcctccgc cggccgtccg ggtgcccgcc gccgcgccgc gccccggccg ggcgtggatg      180

gagggcgccg cgcgccctgc ccgctgctcg gcgtgacgcg ggccccgcgc cccgcgccca      240

ccatgtccta cccgcagggc tacctgtacc aggcgcccgg ctcgctggcg ctctactcgt      300

gcccggccta cggcgcgtcg gctttggcgg ctccgcgcag cgaggagctg gcgcgctcgg      360

cgtcgggctc ggcgttcagc ccctacccgg gctcggcggc cttcacggcg caggcggcca      420

ccggcttcgg gagcccgctg cagtactcgg ccgacgccgc cgccgccgcc gccggcttcc      480

cgtcctacat gggcgcaccc tacgacgcgc acaccaccgg catgaccggc gccatcagct      540

accacccgta cggcagcgcg gcctacccgt accagctcaa cgaccccgcg taccgcaaga      600

acgccacgcg ggacgccacg gccactctca aggcctggct caacgagcac cgcaagaacc      660

cctaccccac caagggcgag aagatcatgc tagccatcat caccaagatg accctcaccc      720

aggtctccac ctggttcgcc aacgcgcgcc ggcgcctcaa gaaggagaac aagatgacct      780

gggccccgag aaacaaaagc gaagatgagg acgaggacga gggcgacgct accagaagca      840

aggacgagag tcccgacaag gcgcaggagg gcacggagac ctcggcagag gacgaaggga      900

tcagcctgca cgtggactcg ctcacggatc actcgtgctc ggccgagtcg gacggggaga      960

agcttccgtg ccgcgccggg gaccccctgt gcgaatcggg ctcggagtgc aaggacaagt     1020

atgacgacct ggaggacgac gaggacgacg acgaggaggg cgagcggggc ctggcgccgc     1080

ccaagcccgt gacctcgtcg ccgcttaccg gcttggaggc gccgctgctg agccccccgc     1140

ccgaggccgc gccccgcggt ggccgcaaga cgccccaggg cagccggacg tctccgggcg     1200

cgccgccccc cgccagcaag cccaagctgt ggtcgctggc cgagatcgcc acgtcggacc     1260

tcaagcagcc gagcctgggc ccgggctgcg ggccaccggg gctgcccgcg gccgccgcgc     1320

cggcctcaac cggggcaccg ccaggaggct cgccctaccc tgcctcgccg ctgctgggcc     1380

gccccctcta ctacacgtcg cccttctacg gcaactacac aaactacggg aacttgaacg     1440

cggcgctgca gggccagggt ctcctgcggt acaactctgc ggccgcggcc cccggcgagg     1500

ccctgcacac cgcgccaaag gcggccagcg acgcgggcaa ggcgggcgcg cacccgctcg     1560

agtcccacta ccggtccccg ggcggcggct acgagcccaa gaaagatgcc agcgagggct     1620

gcaccgtggt tggcgggggc gtccagccct acctatagaa gggccgagca cagcaatgca     1680

agtaagtggg caccctggtg cttcccagac cctgtggagc ctcccagcac caacttgctt     1740

aatgtgtttt tcttgcttct ggtcatgggg ttagaagaca gagcatttca atcttgtcca     1800

gcttttcttt ccttaagggg gaaactatat tttctgtttt atagattccc tctttttggc     1860

acaagttcta tcactccttt acctagggaa ggaaaaaaaa aatatatata tatatgtgtg     1920

tgtgtgtgtg tgtaatatat atatgtatat atatagtaca tgtatatata tagtacatgt     1980

gtatatatat attacacact actgttgttt tcttttgaaa caatagatta ttaaaatctg     2040

ggcatttata tgcaatttag agccattttt actatgctag acacataata gacacatgct     2100

ttgatgagct tgggctacca aaacttggag tagcaaaaac ctttatagat gatgtttgca     2160

aaataagact gaagagacac gaggcgtact agtcttttat cagccctgtc caacctcccc     2220

tccacccatg tccaagtgga caggactctg acattctccc ggggctcaca acagtatctc     2280

aaaaaatatg ttgctttgca acgagtcaga attactaatc atagatcttg aagataagaa     2340

agatttggaa ccacttcaga tcaactcgtt tttataatgg tgttgttgtg gaactgaaag     2400

attggggatg atttggtttt ttccttggtc cacaggtagg tgtcacaatt gctttgaaaa     2460

aaaaaaaaaa aaaaaagtca gcaggccatt ctctcttccc aagctcataa atttacagat     2520

acaacaaaca gatgtctaaa tccagaccac atcttgtgcc actgtaaaag agaaggatcc     2580

acacagcact gtcagcccac agactctaac aattggaaca gactattgtt ggacatatgt     2640

gaatttgttg gcatagtata gtttccccga tgtatgtgtg acttttgaaa acaatctgtt     2700

tttctcagga tatcttgaat tgatcacttc attgccacgg tatatattct ataggtgtga     2760

taggatttac tgtaaagttt atttgtaaaa gatgtacaca gtagaaataa aacgtgatgg     2820

aagaacttga gtacttcaga agtggaaaca aatttgatat ttatttttat aatgatataa     2880

agcttctagt aatttatgca agttgtattg caatggaatc taaacttttt gtaaataaat     2940

tctgcctggt ttttatttga acattgctgg ttatacaatc tttgttggtt gtttaacacg     3000

aattctttac taatttatat cttaaattgt aaataaaaac agactagtct acaataaaaa     3060

aaaaaaaaaa                                                            3070


<210>  1352
<211>  3922
<212>  DNA
<213>  homo sapiens

<400>  1352
ctccttcctg caagaagcgt tgcccgttgg ctagctgctc ggtggggatc tgcctgccct       60

gggggcgccg cccgcgctcc ccgcggtgct ctcgctcctg ggctgcgcca gtccgaggcg      120

gtgccggctc ctttgcctcc ccgagtcgca gatgctgcgg gcgcctccgg gaaaagatct      180

gggcggcgcg ctcgctcgat ggacacagga agatccagaa gctagtggca catctagcaa      240

cagagccaga tcagaaccca gatgctaaac tcctggtgga ctgcagagga gagggattca      300

gtcttctcct gatgtcgatt gcgatttctg ctgggagctc aagacgggcg agctgcccga      360

gatctcttcg agatacccca ggggaggagg agatgggcag gatttagtag gacaactcgg      420

ttactaatga cttggcggct ggctgcgacc ccccgggaaa tcaggtacct gagttgacac      480

cgaaggtgcc taaagatgct gagcggcgtt tggttcctca gtgtgttaac cgtggccggg      540

atcttacaga cagagagtcg caaaactgcc aaagacattt gcaagatccg ctgtctgtgc      600

gaagaaaagg aaaacgtact gaatatcaac tgtgagaaca aaggatttac aacagttagc      660

ctgctccagc ccccccagta tcgaatctat cagctttttc tcaatggaaa cctcttgaca      720

agactgtatc caaacgaatt tgtcaattac tccaacgcgg tgactcttca cctaggtaac      780

aacgggttac aggagatccg aacgggggca ttcagtggcc tgaaaactct caaaagactg      840

catctcaaca acaacaagct tgagatattg agggaggaca ccttcctagg cctggagagc      900

ctggagtatc tccaggccga ctacaattac atcagtgcca tcgaggctgg ggcattcagc      960

aaacttaaca agctcaaagt gctcatcctg aatgacaacc ttctgctttc actgcccagc     1020

aatgtgttcc gctttgtcct gctgacccac ttagacctca gggggaatag gctaaaagta     1080

atgccttttg ctggcgtcct tgaacatatt ggagggatca tggagattca gctggaggaa     1140

aatccatgga attgcacttg tgacttactt cctctcaagg cctggctaga caccataact     1200

gtttttgtgg gagagattgt ctgtgagact ccctttaggt tgcatgggaa agacgtgacc     1260

cagctgacca ggcaagacct ctgtcccaga aaaagtgcca gtgattccag tcagaggggc     1320

agccatgctg acacccacgt ccaaaggctg tcacctacaa tgaatcctgc tctcaaccca     1380

accagggctc cgaaagccag ccggccgccc aaaatgagaa atcgtccaac tcctcgagtg     1440

actgtgtcaa aggacaggca aagttttgga cccatcatgg tgtaccagac caagtctcct     1500

gtgcctctca cctgtcccag cagctgtgtc tgcacctctc agagctcaga caatggtctg     1560

aatgtaaact gccaagaaag gaagttcact aatatctctg acctgcagcc caaaccgacc     1620

agtccaaaga aactctacct aacagggaac tatcttcaaa ctgtctataa gaatgacctc     1680

ttagaataca gttctttgga cttactgcac ttaggaaaca acaggattgc agtcattcag     1740

gaaggtgcct ttacaaacct gaccagttta cgcagacttt atctgaatgg caattacctt     1800

gaagtgctgt acccttctat gtttgatgga ctgcagagct tgcaatatct ctatttagag     1860

tataatgtca ttaaggaaat taagcctctg acctttgatg ctttgattaa cctacagcta     1920

ctgtttctga acaacaacct tcttcggtcc ttacctgata atatatttgg ggggacggcc     1980

ctaaccaggc tgaatctgag aaacaaccat ttttctcacc tgcccgtgaa aggggttctg     2040

gatcagctcc cggctttcat ccagatagat ctgcaggaga acccctggga ctgtacctgt     2100

gacatcatgg ggctgaaaga ctggacagaa catgccaatt cccctgtcat cattaatgag     2160

gtgacttgcg aatctcctgc taagcatgca ggggagatac taaaatttct ggggagggag     2220

gctatctgtc cagacagccc aaacttgtca gatggaaccg tcttgtcaat gaatcacaat     2280

acagacacac ctcggtcgct tagtgtgtct cctagttcct atcctgaact acacactgaa     2340

gttccactgt ctgtcttaat tctgggattg cttgttgttt tcatcttatc tgtctgtttt     2400

ggggctggtt tattcgtctt tgtcttgaaa cgccgaaagg gagtgccgag cgttcccagg     2460

aataccaaca acttagacgt aagctccttt caattacagt atgggtctta caacactgag     2520

actcacgata aaacagacgg ccatgtctac aactatatcc ccccacctgt gggtcagatg     2580

tgccaaaacc ccatctacat gcagaaggaa ggagacccag tagcctatta ccgaaacctg     2640

caagagttca gctatagcaa cctggaggag aaaaaagaag agccagccac acctgcttac     2700

acaataagtg ccactgagct gctagaaaag caggccacac caagagagcc tgagctgctg     2760

tatcaaaata ttgctgagcg agtcaaggaa cttcccagcg caggcctagt ccactataac     2820

ttttgtacct tacctaaaag gcagtttgcc ccttcctatg aatctcgacg ccaaaaccaa     2880

gacagaatca ataaaaccgt tttatatgga actcccagga aatgctttgt ggggcagtca     2940

aaacccaacc accctttact gcaagctaag ccgcaatcag aaccggacta cctcgaagtt     3000

ctggaaaaac aaactgcaat cagtcagctg tgaagggaaa tcatttacaa ccctaaggca     3060

tcagaggatg ctgctccgaa ctgttggaaa caaggacatt agcttttgtg tttgtttttg     3120

ttctcccttt cccagtgtta atgggggact ttgaaaatgt ttgggagata ggatgaagtc     3180

atgattttgc ttttgcaagt tttcctttaa attatttctc tctcgctctc ctcccctcct     3240

tttttttttt tttttttttt tctttttccc ttctcttctt aggaaccatc agtggacatg     3300

aatgtttcta caatgcattt cttcatagat tttgtttatg gttttgtttc ttttttcttc     3360

tttgtttttc agtgtgggag tgggaagagg agattatagt gactgaagaa agaataggca     3420

aacttttcaa atgaaaatgg atatttagtg tattttgtag aagatctcca aagatctttt     3480

gtgactacaa cttcttttgt aaataatgat atatggtatt tccatcgtca gttaccgagt     3540

atagccactg ggtatcacta ctttgtgtta aagtgccttc gcactttaag tacattactt     3600

aaatgttgct tttagctttg ataaattgaa aatattttaa tgtgttgtat ttttgaaatt     3660

gaaaacactg taaaatagat tgatgtgtca gctatattaa gtcaacgtac agtttgcttg     3720

agttatagaa accagcctgt catcaaatga ttctagttct aggactttgt aggcttaact     3780

ataaaatatt tcctttcctc tgggtttaag tgattttatt taagtcaact aaggggattt     3840

aacagtggac tagaggtaat aagccacctc agtcaggatt aataattcat taataaaata     3900

tatttaaccc aaaaaaaaaa aa                                              3922


<210>  1353
<211>  2722
<212>  DNA
<213>  homo sapiens

<400>  1353
ttggcgcgta aaagtggccg ggactttgca ggcagcggcg gccgggggcg gagcgggatc       60

gagccctcgc cgaggcctgc cgccatgggc ccgcgccgcc gccgccgcct gtcacccggg      120

ccgcgcgggc cgtgagcgtc atggccttgg ccggggcccc tgcgggcggc ccatgcgcgc      180

cggcgctgga ggccctgctc ggggccggcg cgctgcggct gctcgactcc tcgcagatcg      240

tcatcatctc cgccgcgcag gacgccagcg ccccgccggc tcccaccggc cccgcggcgc      300

ccgccgccgg cccctgcgac cctgacctgc tgctcttcgc cacaccgcag gcgccccggc      360

ccacacccag tgcgccgcgg cccgcgctcg gccgcccgcc ggtgaagcgg aggctggacc      420

tggaaactga ccatcagtac ctggccgaga gcagtgggcc agctcggggc agaggccgcc      480

atccaggaaa aggtgtgaaa tccccggggg agaagtcacg ctatgagacc tcactgaatc      540

tgaccaccaa gcgcttcctg gagctgctga gccactcggc tgacggtgtc gtcgacctga      600

actgggctgc cgaggtgctg aaggtgcaga agcggcgcat ctatgacatc accaacgtcc      660

ttgagggcat ccagctcatt gccaagaagt ccaagaacca catccagtgg ctgggcagcc      720

acaccacagt gggcgtcggc ggacggcttg aggggttgac ccaggacctc cgacagctgc      780

aggagagcga gcagcagctg gaccacctga tgaatatctg tactacgcag ctgcgcctgc      840

tctccgagga cactgacagc cagcgcctgg cctacgtgac gtgtcaggac cttcgtagca      900

ttgcagaccc tgcagagcag atggttatgg tgatcaaagc ccctcctgag acccagctcc      960

aagccgtgga ctcttcggag aactttcaga tctcccttaa gagcaaacaa ggcccgatcg     1020

atgttttcct gtgccctgag gagaccgtag gtgggatcag ccctgggaag accccatccc     1080

aggaggtcac ttctgaggag gagaacaggg ccactgactc tgccaccata gtgtcaccac     1140

caccatcatc tcccccctca tccctcacca cagatcccag ccagtctcta ctcagcctgg     1200

agcaagaacc gctgttgtcc cggatgggca gcctgcgggc tcccgtggac gaggaccgcc     1260

tgtccccgct ggtggcggcc gactcgctcc tggagcatgt gcgggaggac ttctccggcc     1320

tcctccctga ggagttcatc agcctttccc caccccacga ggccctcgac taccacttcg     1380

gcctcgagga gggcgagggc atcagagacc tcttcgactg tgactttggg gacctcaccc     1440

ccctggattt ctgacagggc ttggagggac cagggtttcc agagatgctc accttgtctc     1500

tgcagccctg gagccccctg tccctggccg tcctcccagc ctgtttggaa acatttaatt     1560

tatacccctc tcctctgtct ccagaagctt ctagctctgg ggtctggcta ccgctaggag     1620

gctgagcaag ccaggaaggg aaggagtctg tgtggtgtgt atgtgcatgc agcctacacc     1680

cacacgtgtg taccgggggt gaatgtgtgt gagcatgtgt gtgtgcatgt accggggaat     1740

gaaggtgaac atacacctct gtgtgtgcac tgcagacacg ccccagtgtg tccacatgtg     1800

tgtgcatgag tccatgtgtg cgcgtggggg ggctctaact gcactttcgg cccttttgct     1860

ctgggggtcc cacaaggccc agggcagtgc ctgctcccag aatctggtgc tctgaccagg     1920

ccaggtgggg aggctttggc tggctgggcg tgtaggacgg tgagagcact tctgtcttaa     1980

aggttttttc tgattgaagc tttaatggag cgttatttat ttatcgaggc ctctttggtg     2040

agcctgggga atcagcaaag gggaggaggg gtgtggggtt gataccccaa ctccctctac     2100

ccttgagcaa gggcaggggt ccctgagctg ttcttctgcc ccatactgaa ggaactgagg     2160

cctgggtgat ttatttattg ggaaagtgag ggagggagac agactgactg acagccatgg     2220

gtggtcagat ggtggggtgg gccctctcca gggggccagt tcagggcccc agctgccccc     2280

caggatggat atgagatggg agaggtgagt gggggacctt cactgatgtg ggcaggaggg     2340

gtggtgaagg cctcccccag cccagaccct gtggtccctc ctgcagtgtc tgaagcgcct     2400

gcctccccac tgctctgccc caccctccaa tctgcacttt gatttgcttc ctaacagctc     2460

tgttccctcc tgctttggtt ttaataaata ttttgatgac gtttgggccg ggttttggga     2520

ctctgttggg aacatttcgg ggcgggagag gccaaggttg ctggggaaat gcccattctc     2580

cacttccctt ctccctgtcc gtgcccgatt tgatttgagc ctcataactc gaagaaaggt     2640

cagcttcctc gctgttttgg tcctaactca aaagcagatc cagtaaaggt ttttgttgta     2700

aaaaaaaaaa aaaaaaaaaa aa                                              2722


<210>  1354
<211>  6382
<212>  DNA
<213>  homo sapiens

<400>  1354
gcgcttgttt ttcccttggg acccgggtcc acacggcggg gtcgcccgtc catctccggc       60

tcgcccgcgg ggcccatcgt cgacgttagc ggccgttctc cgagccgact gacccatcct      120

tggcgctgcc gccgcgcgct tgttctcctc cctcgccccg ccttcatcct ccccgttcac      180

ggaaacgaca gctgcggctg cggggctggc gccgcctccc tccacctacc acgtctgccc      240

tcgccgctct agccctgcgc cccagcccgg ccgcggcacc tccgcctcgc cgccgctagg      300

tcggccggct ccgcccggct gccgcctagg atgaatatca tggacttcaa cgtgaagaag      360

ctggcggccg acgcaggcac cttcctcagt cgcgccgtgc agttcacaga agaaaagctt      420

ggccaggctg agaagacaga attggatgct cacttagaga acctccttag caaagctgaa      480

tgtaccaaaa tatggacaga aaaaataatg aaacaaactg aagtgttatt gcagccaaat      540

ccaaatgcca ggatagaaga atttgtttat gagaaactgg atagaaaagc tccaagtcgt      600

ataaacaacc cagaactttt gggacaatat atgattgatg cagggactga gtttggccca      660

ggaacagctt atggtaatgc ccttattaaa tgtggagaaa cccaaaaaag aattggaaca      720

gcagacagag aactgattca aacgtcagcc ttaaattttc ttactccttt aagaaacttt      780

atagaaggag attacaaaac aattgctaaa gaaaggaaac tattgcaaaa taagagactg      840

gatttggatg ctgcaaaaac gagactaaaa aaggcaaaag ctgcagaaac tagaaattca      900

tctgaacagg aattaagaat aactcaaagt gaatttgatc gtcaagcaga gattaccaga      960

cttctgctag agggaatcag cagtacacat gcccatcacc ttcgctgtct gaatgacttt     1020

gtagaagccc agatgactta ctatgcacag tgttaccagt atatgttgga cctccagaaa     1080

caactgggaa gttttccatc caattatctt agtaacaaca atcagacttc tgtgacacct     1140

gtaccatcag ttttaccaaa tgcgattggt tcttctgcca tggcttcaac aagtggccta     1200

gtaatcacct ctccttccaa cctcagtgac cttaaggagt gtagtggcag cagaaaggcc     1260

agggttctct atgattatga tgcagcaaac agtactgaat tatcacttct ggcagatgag     1320

gtgatcactg tgttcagtgt tgttggaatg gattcagact ggctaatggg ggaaagggga     1380

aaccagaagg gcaaggtgcc aattacctac ttagaactgc tcaattaagt aggtggacta     1440

tggaaaggtt gcccatcatg actttgtatt tatatacaat taactctaaa taaagcaggt     1500

taagtatctt ccatgttaat gtgttaagag actgaaaata ccagccatca gaaactggcc     1560

tttctgccaa taaagttgca tggtaaatat ttcattacag aatttatgtt agagctttca     1620

tgccaagaat gttttcttac aaaattctct ttttattgag gtttcactaa taagcagctt     1680

ctacttttga gcctcaactt aaagcagaac tgttttctac tggatttttc attaacagca     1740

agctttttct tttatgtaaa ataaatctat tgtgaattga tatcagcgac tcatttatta     1800

ggtataaata atagccaaag aataaaatta aaatttattt taaactttcg gtcttaaaaa     1860

gagctgtagg atataaacct cttttgtgaa aagtagaatt ttctgaatgc tttcatagac     1920

aaaaacgcat ttaaactatg tttacctggt tttccaacag aaatcaaatg attttaatat     1980

tatgttttga tgggttattt tcagagttgt ttggtttttt aaacactact gaatggtttc     2040

ttttaaattt aagaacaact agttcttgaa aagcaatacc gtatttctct gataaatttg     2100

tagttaaggt tctagaaaat ctaggacaaa tttacttcat taaacataaa gtttttaaga     2160

ttattcagtt ggcacaattt aatgcataat tgggattgga tccatttact gtactgtggt     2220

acagtaaaga gaatgtgttc ttattgaaca gcagatttgt atacaaatac ggaataatgc     2280

aactacatta taaattgtat acgaacaaaa taaattgggt cactctgagc ttactattaa     2340

aacattgaaa atttattaat gaacacaggc tatcttgatg aggatctctg cttatgaaac     2400

acatactaat gaaattatta gtgacacatt ggaagctaga aaattgctgt tggggccatt     2460

gctataaatc attgtttcca tgttaagact tctgttctaa ttcattcatt caacaaacat     2520

ttgttgaggg ccagatactg tgctggtcaa ctggggatac tgtcctgaac aatatgcaca     2580

cagttcttgc ccctgcagag cttaaagacc attaaaggat acagaaaatt aagcaattat     2640

cctatagtag gattcgtggt gtgatgggga aaatacaagg tactgtattt gggagtcatg     2700

taactccagt tttgggagtg agagagggtc tggggaagaa ctgttccaga taaaaagatg     2760

tgtaaccaag atagcatagc acattctgac aactaaagca atttactcta acttaagcat     2820

gaagtacaaa agtatagttc atttattgag ggaatgttaa gctattaaaa tgatactttt     2880

tggtactttt aaaaaaatga atacttaaac accgttttaa aattttgtgt taagagctcc     2940

taataagaac ttggtaaaca tgttgacaat ttaactcaca gtctaaactt taaaagtagt     3000

agttaccctt ttatttctgt gccatgagac aaattcttct gcagttttat agttgtacaa     3060

gatgttttga ctcactctca attgccatat tcttaaagaa accctgaaaa gctgctcaag     3120

ctggtcagtt ttctgtaaaa ccaagtaaat gaaattttct ctcccctcag aaaggaagtt     3180

ctacagccta gagtaccatc tattgtgttt tataagtcca gatttaggct ttgaaagatc     3240

ataccaaaac ttcagatcga cttaaacagc aactatgaat taggtttatg ggaaatgtag     3300

taatacaggg gaaagaatat cggtaatgga gtgaaatggt cctgggttca aatccagtct     3360

tcctcacata ttgtgctctt taagcttcaa atgagatgta taactgcctt ttccttacca     3420

gtaaaatgag gacaataatt atgacaccat agggtggttg tgaggattag caaatgttat     3480

cttgtatttc aggtgccttt cagggaaagg cttggcacat agtaaacaca tcctgtaaat     3540

atcagtttcc ccttgttagc ccctgtagca tcctgaccta ccaagtctat aggccttgca     3600

tatcactgtg caccagagat acctctttta catctgggct ctgttttctc tctatcaatc     3660

ctatcctcca ccctctttaa atcagacccc aggtttaacc ttcccacagt cagtataaat     3720

catttttcag aactttcagc tttccatcaa gtgaaagttg attttagtta cccagtaatg     3780

tacagaaacc ttcaataatg ttaagcttca aaggcttctg gtacgtttgt ctaccacaga     3840

accaccacaa tatatatgct tgttcttagg tttattgctt tttattttaa tggggtttgg     3900

ttgtttgggt tttattttgg ttttggctta ttttaaagtc aagtttagtt tttactcagg     3960

taaaggcctg aagtttcttg ggcgtggaag aaaaagcttg ggaagcctat taattcatgg     4020

tgcagttcag aattgtttaa ataagctctg tgccactgag cttaatctga aagtatagtg     4080

acatgtgaag gatgcacata tgaatgaaaa actaaaataa ttgtaggctc ttctataaat     4140

gaaaaaaaaa gtgattggat tgtgtctacc tttttcctca aagtaatcta acctaaacgg     4200

tcatggtgtt aaaacttttt atggtgctaa tcagaaaaat tgatgttgca agaaatgagg     4260

tctcaaaaat gggaatgtgc ctcctcactc tgcgtcacat gggaaataaa tcctgaggcc     4320

aggatcacca gtggggtaga gtcatcttca tagtctcctg ttatcctccc cctgaacaaa     4380

gaacaaagtg agactgggaa gctagtgttg gggaaacatt tctgggataa actgtggagt     4440

ggagaagaca atggagggca aggcaaaaac ccacagactt gtttacccat agaggcccca     4500

ctcacctcca tgctgacaga attccagaaa aattccttcc ctatctccca aacacctgaa     4560

attctgaaat attgccctac tatttagcac tttaagcttc agtgaggtgc tgtaatggag     4620

agatagcttc atagtttagc ctatagccaa ctttgcctca agacctccag ataagatgaa     4680

gtggctttta cctcatgtga gtctcaaacg ctggagagag agttccacaa ccacccctgc     4740

cctttctccc atattacgct cattagaaag tctactcagg gctgggtgcc gtggctcatg     4800

cctgtaatcc cagcactttg gaggctgagg cgggtggatc atctgaggtc aggagttcga     4860

gaccagcctg gccaacatgg ggaaaccctg tctctactga aaatataaaa attagccggg     4920

catggtggcg tgcacctgta attccagcta ctcgggaggc tgaggcagga gaatcacttg     4980

aaccccagag gcagaggcta cagtgagcca agattgcacc actgcactcc aacctgggtg     5040

atagaataag actcttgtct caaggaaaga aaaaatgtct actcagtaga gcagtgattg     5100

gcaaagtgtg agaccccaga ccggcaatat tggcatctcc tggagacttg tttaaaatgc     5160

tgattactat tttcaagaac tttctacctt catttttact tattttttgt tttcaagggc     5220

tcatggaatc agtcttccat gtgacagctt tttaaatatt ttaagacaaa aactgagtct     5280

tctaatctta attgtgttct agcagtagtc attgtaatta tagttatttt tataatttat     5340

ttgtttagtg tatatctgtc actctagaat gtaggctccc tgagataaaa actataattc     5400

ttttgatggc agttacattc ccaactctta gcacaagatc taggacatag tatgaactca     5460

ataaattttt gttgaatgaa agaaaaatgc aaatttataa gccttttcag agacctactg     5520

aatcaaactc tgagagtgga gcccagcaat ctgttgtaaa agctgtttga gtaatactgt     5580

tgcactctaa gcttgagaac cactgcaata gaactaagag aacattcatt tcaccttcag     5640

gcctattctc tgacatcact tgaaaaatcc tctctgcctt ctgtaaccct taaccaacaa     5700

cagtgccctg tccatgtagg ggaaacttct gggctgtatt acaagtgggt aggaaggtat     5760

aaggatatca tagtgggaag tattgcttag aatgccagta cttgtttgct gtggaaggtt     5820

tctaggaatg gattgcttag tctaaagtaa gcactaccac catccacgtt ttcactcaac     5880

acagtgcctt ttaattggtg actaacatca aaacaccttg acaaaccgtt aaaacagtat     5940

cagaaaccat gtgtacatcc ctgtgcctct tagattgcta agttctgctc tcattcttac     6000

ttcaaaggac actttttaaa gaattgttaa tgctttttta taatacaagt catagccctg     6060

ttggcaaaaa gaaaaaagat tcagtgagaa agaaaaatca ctgataattc catcatccag     6120

ggagaaccac tgttatttaa gtatatggcc ttccagactt ttctgtgcat ttatagatat     6180

ttttaatggg atcaaagtgt acatactgtt ttgtaacttt ttttcactca acaataccat     6240

gactgtcttg ctgtgtcaag tatatttcta catctcttaa tggctgcatg atattccatc     6300

atatgtgcca cattttatta aactactgtt caatttttag gtttccaact ttcattaata     6360

aagtgcttta aagaacaaaa aa                                              6382


<210>  1355
<211>  2417
<212>  DNA
<213>  homo sapiens

<400>  1355
atgcgctgag cttcggttgg cccggcttcc ttgaggcgta agctcggtct gtccaatgag       60

gagcgagcgt cgcgggggcc gtcgggaagg gcggccgacc catataagca gcctgcgggg      120

cgttccctcg ggttgtggtt ggtgtgcggg tttcggttgg aggactcgtt ggggaggtgg      180

cctgcgcttg tagagactgc atccccgaga cgatggcgga gggagataat cgcagcacca      240

acctgctggc tgcagagact gcaagtctgg aagaacagct gcaaggatgg ggagaagtga      300

tgctgatggc tgataaagtc ctccgatggg aaagagcctg gtttccacct gccatcatgg      360

gtgtggtttc tttggtgttt ctgattatct actatctaga tccatctgtt ctgtccggcg      420

tttcctgttt tgttatgttt ttgtgcttgg ctgactacct tgttcccatt ctagcgccta      480

gaatttttgg ctccaataaa tggaccactg aacaacagca aagattccat gaaatttgca      540

gcaatctagt aaaaactcga cgcagagctg tgggttggtg gaaacgcctc ttcacactaa      600

aggaagaaaa acctaagatg tacttcatga ccatgatcgt ttcccttgct gcggttgctt      660

gggtgggaca acaagtccac aacctgcttc tcacctacct gatagtgact tccttactat      720

tgcttcctgg actaaaccaa catggaatca ttttgaagta cattggaatg gccaagaggg      780

agataaacaa acttctcaaa caaaaagaaa agaaaaacga atgattcatc tgctttaatc      840

agtgtgatta atgcagcacc cattgccccg ggaaccgttt ctgctgtact atctggatac      900

taaaatgtta cggaagtagc tctttgttct ccctcactct gcccttagtt aatagaaatt      960

cagactcgcc aagtaaggct tcgtgcatag tgtcttcatg tcgcgtatag ttgagcgcgt     1020

tcttagcagt tggcttcatg gacaactcat tagtgttttg acttttctta cccagcgtta     1080

attgaattct tgcttttaga caacttcctt tttgtagtgg tgaaccttgc cctttagtac     1140

agttcaagtg aatctggata attgttcatc tttgctttag cttagatacc atgtagtggt     1200

ctgtggctac aggaagctgg ttctgtctgc ttccacagtc tgcttaaaaa actgtctgac     1260

ttcgtgaata tagagaccaa gtttaccact tctgatgaag agaccaatta agattcattc     1320

ctcattctgt ttctttccag tgggagaaga gtccccatga aataagatga aactgattcc     1380

atgcactagt acatgtaggc ttctcccttg tgcaaagctt agcaatttgt aggaaacttt     1440

gatctttttg tccaagaaaa ggaatgtctg acaggcttaa gctttcgtcc ccttgcactt     1500

agactcgaag ttagtaaatc cttaaaggct ttttaatagc agacttccaa aagattgcat     1560

ttaggatttc tagcatgctt ttaatttcag attttcagct gacattagct atagtataca     1620

gtaggttaag actcatgtct atgactttca ctctaagact ggcaaaagga cagcagtctt     1680

ctatgtttag tcaatattca tttcagtaga agataatctt atctaatttt tgagaccaga     1740

ataagccttt taaggtaaac ctcaaaatta tcattttatg gtaatactga ccattttagt     1800

cccctaggtt tgacatggga gatagtgact acactggtgt ctgacttttt tcctagagat     1860

ttctccctga aaaatacaag ggctgttggt gagagcagac ttgaggtgat gatagttggc     1920

ctctggtcta caaagatttc ataactcctt ggaaagcttc ttataatcat tcttaacttc     1980

ttggtagcta gaaatttaga gtagttgaaa tctttaggaa tgaacttctg agggccaaaa     2040

aatgtgactg acgggaacaa ttcttaaact gattaactag ctgtaatata gttttgtgaa     2100

tttattgcac tgatgttgta ccttgtggta tatctgtccc tattaaataa gtgttgtttt     2160

ctcctcttta atattgctgt gaacagtggt gcccattgta gcatatgttt gatttttttt     2220

tattatttca taagaaaact acgttaattt taccttactt tcattgtaaa taagcctgtc     2280

ttcctatctg gattttttgt gtgcatacat attctactga ttaactactt ttgcagtttt     2340

aatcctgtat tatttcttct actttgtttt gtgtaaaagg ggaaaaaata aaaaaagctg     2400

gaatcttcaa aaaaaaa                                                    2417


<210>  1356
<211>  937
<212>  DNA
<213>  homo sapiens

<400>  1356
tgcgtgccgc cgttgatccg gtgctgcagt gaggaggtgg ttcttgcccg tgttgtgtgt       60

gtgtgtgagt gagagagcga gtgagtgagt gagtgagtgt gtgtgtgggg gggactcggc      120

ttgttgttgt cggtgacttc cccctcccct tcaccccttc ccctccccgc cgccgctgca      180

gtggccgctc cctgggccgt aggaaatgag cgataacgat gacatcgagg tggagagcga      240

cgaagagcaa ccgaggtttc aatctgcggc tgacaaacgg gctcatcata atgcactgga      300

acgaaaacgt agggaccaca tcaaagacag ctttcacagt ttgcgggact cagtcccatc      360

actccaagga gagaagctct atttcctctt ttggaaattg tgtactcctg tccttcatcg      420

tcaaagtttg atgcagaaat gccacacctt catttcaagc taccaagtgc acaagaaaaa      480

agaatgcaag atttaaaaaa tgattgtttt gaccccttac acaaatgtct tactcctggc      540

tttaattaag ctgcttgagg gctgatagct ctgccttacc ctggtaatca gcaaaatggt      600

cctgtggctg gggaggccct ggcagcagga agccttcaag gagccatggg tctgtgctga      660

ctctggcctt acaaccttcc agcctccttt gctggcattg atggggttcc atttttgaat      720

gaactagttt aatgtggatc caaatttatt gtgcatattc tttcgttttg gttttcaaaa      780

gatggcttat tcacatggaa atgtacacca gtttagccct gggccctccc tttaccttca      840

tatgtgtaaa agcttacaca ggtttcagaa aataaatggt ttcattttct ctaaaataac      900

tagtacaaaa taaaacagat gtcagttgtt gagtcca                               937


<210>  1357
<211>  560
<212>  DNA
<213>  homo sapiens

<400>  1357
tgcgtgccgc cgttgatccg gtgctgcagt gaggaggtgg ttcttgcccg tgttgtgtgt       60

gtgtgtgagt gagagagcga gtgagtgagt gagtgagtgt gtgtgtgggg gggactcggc      120

ttgttgttgt cggtgacttc cccctcccct tcaccccttc ccctccccgc cgccgctgca      180

gtggccgctc cctgggccgt aggaaatgag cgataacgat gacatcgagg tggagagcga      240

cgaagagcaa ccgaggtttc aatctgcggc tgacaaacgg gctcatcata atgcactgga      300

acgaaaacgt agggaccaca tcaaagacag ctttcacagt ttgcgggact cagtcccatc      360

actccaagga gagaagggaa caaagatgaa gttaaccctc ccacctgtct ttccttatga      420

acacttgcct tttccaactg ttttctgcca tggctaatca gaaaaagttt cttaaggaaa      480

tggtggcaaa aaaaaaaaaa aaaagacaca aaggtaacaa acaaagctgg acctatttat      540

aatgttccag taagcagaag                                                  560


<210>  1358
<211>  2018
<212>  DNA
<213>  homo sapiens

<400>  1358
tgcgtgccgc cgttgatccg gtgctgcagt gaggaggtgg ttcttgcccg tgttgtgtgt       60

gtgtgtgagt gagagagcga gtgagtgagt gagtgagtgt gtgtgtgggg gggactcggc      120

ttgttgttgt cggtgacttc cccctcccct tcaccccttc ccctccccgc cgccgctgca      180

gtggccgctc cctgggccgt aggaaatgag cgataacgat gacatcgagg tggagagcga      240

cgctgacaaa cgggctcatc ataatgcact ggaacgaaaa cgtagggacc acatcaaaga      300

cagctttcac agtttgcggg actcagtccc atcactccaa ggagagaagg catcccgggc      360

ccaaatccta gacaaagcca cagaatatat ccagtatatg cgaaggaaaa accacacaca      420

ccagcaagat attgacgacc tcaagcggca gaatgctctt ctggagcagc aagtccgtgc      480

actggagaag gcgaggtcaa gtgcccaact gcagaccaac tacccctcct cagacaacag      540

cctctacacc aacgccaagg gcagcaccat ctctgccttc gatgggggct cggactccag      600

ctcggagtct gagcctgaag agccccaaag caggaagaag ctccggatgg aggccagcta      660

agccactcgg ggcaggccag caataaaaac tgtctgtctc catcgtctca tcctcctttc      720

agttcgttgg tagagccctc agaaccattt aagagactct ttatttttct ctttctccct      780

ttttttttta aatttttatt tttacgtaga agctcttgga caacagctct cgttctcctt      840

ccccatttcc actgtatatt ttttaatgta ttcccttcag ggattccctg tccccaacag      900

gaatttttaa accaaaacac cccaacttgg cagctttttc tgtggaggac agacggccgg      960

ccggacctct gagcacatag tgtcctgccc accctaccag ctcctccagc cctgccgggc     1020

acatgcccgg gggacgcctg ccctgcccag gtggcctcct ggcccgccct cacctctgat     1080

agactttgtg aatctgaact gctctacttt gagaagatga ccggtttgga gtaatcagaa     1140

tgaaccctcc tcctttttaa gggttttttt tttttccttt ttctaaaaag ctatgtatcg     1200

ctcctattga aagaccagat ccttagagaa gtttgtggta taaaaaggaa gtggggacag     1260

attcgcagca cagagtcgct ggcatgtttc actcctgctt ctctcagcca gctgtttaag     1320

cctgcggcgc cagcctcacg gagggccgtg tgacactctc gtggtatgta tgggagatgg     1380

cagcagtgaa gcagcagcca ccagggagtg gccatttggg gttgggacag ggagggtgtt     1440

ttgggtggca tagaggtttt gtattgaggg ccagtgatga tgttttgata tttatttcct     1500

gctacttaaa tttgaatctg agtgaattgt acctatttct gatgatgtcg gtcttgcaaa     1560

gcgacagatt cataaagtaa tgatgaaatc tttctttctt cccgtgtgta tttctaagaa     1620

atagagccaa ctgattttgt atgtaaatac caagagcaat ttacctggta ctaaacccgc     1680

accccagtgc ggacccttcc cagccctcat cccacttcct ttcctactgt cctggaacct     1740

gtctccattg tgtgatccag ccctggttct ggctgtggtc agcagatgcc agtgaagggt     1800

tttgtgtgtt taggcctcat ttctttgtct ttttcctact ccgttcctgg catttgctga     1860

tttctagtgt atactctgta gtctcagttc gtgtttgatt ccattccatg gaaataaaaa     1920

gtatgttgta catactgccg aagaattgtc ttgcaagtta aggcttcccc ctttactata     1980

agactataaa taaaaactta ttttatcctt cttaaaaa                             2018


<210>  1359
<211>  9774
<212>  DNA
<213>  homo sapiens

<400>  1359
agatgcaggg aagttttgcc tcttcctgaa aattatatta ttagcttttt aaaaatcagg       60

atgactgcta gttttgttta aagtatttgt tctggaaata ctaaagttgg agtctaccag      120

actgaggtta gaagcatttt ctttggcagc aagaagataa ttttatagaa gccatgcctg      180

ttcttggggt tgcctcaaaa ctgaggcagc cagctgttgg gtcaaagcct gtgcatactg      240

ctcttccgat accaaatctt ggcactactg ggtcacagca ctgttcttca agacctttgg      300

aacttactga aacagagagc tccatgcttt cttgtcagct tgcgttaaaa tcaacctgtg      360

aatttggaga gaagaaaccc ctccaaggaa aagccaagga gaaagaagac agcaagattt      420

acactgactg ggccaaccac tacctagcaa aatcaggcca caagcggctg atcaaggact      480

tgcaacaaga cattgcagat ggagtactcc tagcagaaat catccagatt attgcaaatg      540

aaaaagttga agatatcaat ggatgtccta gaagtcagtc tcagatgatt gaaaatgttg      600

atgtctgcct tagttttcta gcagccagag gggtaaatgt tcaaggtcta tctgctgaag      660

aaataagaaa tggaaactta aaagccattc tagggctgtt tttcagttta tctcgctaca      720

agcagcaaca acaccatcaa caacagtact atcagtcctt ggtggaactt cagcagcgag      780

ttactcacgc ttcccctcca tcggaagcca gccaggccaa aacccagcaa gatatgcagt      840

ccagtctggc agccagatat gcaactcagt ctaatcacag tggaattgca accagtcaaa      900

aaaagcctac taggcttcca gggccctcta gggtgcctgc tgcaggaagc agcagcaagg      960

tccagggagc ctctaattta aataggagaa gtcagagctt taacagcatt gacaaaaaca     1020

agcctccaaa ttatgcaaat ggaaacgaaa aagattcctc caaaggacct caatcgtctt     1080

caggtgtaaa tggtaacgtg cagcctccca gtactgctgg gcagcctcct gcctctgcca     1140

tcccttctcc aagtgccagc aagccctggc gcagcaagtc catgaatgtc aaacacagtg     1200

ccacctccac catgttgact gtaaagcagt caagtacagc cacctccccc acaccatctt     1260

cagacagact gaagccacct gtctcagaag gggtcaaaac tgctccctca ggacagaaat     1320

ccatgcttga gaaattcaag ctagtcaatg cccggactgc tttacgcccc ccgcagcctc     1380

ccagttcagg acctagtgat ggtgggaagg atgatgatgc cttttctgaa tctggtgaaa     1440

tggaaggttt taacagtggt ctgaatagtg gtggctcaac aaatagcagt cccaaagtgt     1500

cacctaagtt ggcccctcca aaagctggaa gcaaaaatct cagcaataaa aagtctttgc     1560

tacagccaaa ggaaaaagaa gaaaagaaca gggacaaaaa taaagtttgc actgaaaaac     1620

cagtcaaaga agagaaggat caggtgacag agatggctcc aaaaaagacc tccaaaattg     1680

caagcttgat ccctaagggc agcaagacaa cagcagctaa gaaggaaagc ttaattccgt     1740

cttccagtgg tattccaaaa ccaggctcta aagttccaac agtaaagcaa accatttcac     1800

ctggcagcac agcaagcaaa gagtctgaga aattcaggac taccaagggg agcccttccc     1860

agtccttatc taagcctata accatggaga aagcaagtgc ttctagttgt cctgcccctt     1920

tggaaggaag ggaagctggc caagcttctc cttctggttc ctgtaccatg acagtggcac     1980

aaagcagtgg gcagagcaca ggaaatggtg ctgtccaact ccctcaacag cagcaacata     2040

gccacccgaa taccgcgaca gtggcaccat tcatttacag ggcacattca gaaaatgaag     2100

gtaccgcttt accatcggct gactcctgta ccagtcctac aaagatggac ttatcatata     2160

gtaagactgc taagcagtgc ctggaggaga tatctggtga agaccctgaa acaagaagaa     2220

tgagaacagt taaaaacata gcagacttga ggcagaattt agaagagact atgtccagtc     2280

ttcgtgggac tcagataagc cacagcaccc tggagacaac atttgacagc actgtgacaa     2340

cagaagttaa tggaaggacc atacccaact tgacaagtcg acccaccccc atgacctgga     2400

ggttgggcca ggcatgtccg cgacttcagg cgggagatgc tccctccctg ggtgctggct     2460

atcctcgcag tggtaccagt cgattcatcc acacagaccc ctcgaggttc atgtatacca     2520

cgcctctccg tcgagctgct gtctctaggc tgggaaacat gtcacagatt gacatgagtg     2580

agaaagcaag cagtgacctg gacatgtctt ctgaggtcga tgtgggtgga tatatgagtg     2640

atggtgatat ccttgggaaa agtctcagga ctgatgacat caacagtggg tacatgacag     2700

atggaggact taacctatat actagaagtc tgaaccgaat accagacaca gcaacttccc     2760

gggacatcat ccagagaggg gttcacgatg tgacagtgga tgcagacagc tgggatgaca     2820

gcagttcagt gagcagtggt ctcagtgaca cccttgataa catcagcact gatgacctga     2880

acaccacatc ctctgtcagc tcttactcca acatcaccgt cccctctagg aagaatactc     2940

agctgaggac agattcagag aaacgctcca ccacagacga gacctgggat agtcctgagg     3000

aactgaaaaa accagaagaa gattttgaca gccatgggga tgctggtggc aagtggaaga     3060

ctgtgtcctc tggacttcct gaagaccccg agaaggcagg gcagaaagct tccctgtctg     3120

tttcacagac aggttcctgg agaagaggca tgtctgccca aggaggggcg ccatctaggc     3180

agaaagctgg aacaagtgca ctcaaaacac ccgggaaaac cgatgatgcc aaagcttctg     3240

agaaaggaaa agctccccta aaaggatcat ctctacaaag atctccttca gatgcaggaa     3300

aaagcagtgg agatgaaggg aaaaagcccc cctcaggcat tggaagatcg actgccacca     3360

gctcctttgg ctttaagaaa ccaagtggag tagggtcatc tgccatgatc accagcagtg     3420

gagcaaccat aacaagtggc tctgcaacac tgggtaaaat tccaaaatct gctgccattg     3480

gcgggaagtc aaatgcaggg agaaaaacca gtttggacgg ttcacagaat caggatgatg     3540

ttgtgctgca tgttagctca aagactaccc tacaatatcg cagcttgccc cgcccttcaa     3600

aatccagcac cagtggcatt cctggccgag gaggccacag atccagtacc agcagtattg     3660

attccaacgt cagcagcaag tctgctgggg ccaccacctc gaaactgaga gaaccaacta     3720

aaattgggtc agggcgctcg agtcctgtca ccgtcaacca aacagacaag gaaaaggaaa     3780

aagtagcagt ctcagattca gaaagtgttt ctttgtcagg ttcccccaaa tccagcccca     3840

cctctgccag cgcctgtggt gcacaaggtc tcaggcagcc aggatccaag tatccagata     3900

ttgcctcacc cacatttcga aggttgtttg gtgccaaggc aggtggcaaa tctgcctctg     3960

cacctaatac tgagggtgtg aaatcttcct cagtaatgcc cagccctagt accacattag     4020

cgcggcaagg cagtctggag tcaccgtcgt ccggtacggg cagcatgggc agtgctggtg     4080

ggctaagcgg cagcagcagc cctctcttca ataaaccctc agacttaact acagatgtta     4140

taagcttaag tcactcgttg gcctccagcc cagcatcggt tcactctttc acatcaggtg     4200

gtctcgtgtg ggctgccaat atgagcagtt cctctgcagg cagcaaggat actccgagct     4260

accagtccat gactagcctc cacacgagct ctgagtccat tgacctcccc ctcagccatc     4320

atggctcctt gtctggactg accacaggca ctcacgaggt ccagagcctg ctcatgagaa     4380

cgggtagtgt gagatctact ctctcagaaa gcatgcagct tgacagaaat acactaccca     4440

aaaagggact aagatatacc ccatcatctc ggcaggccaa ccaagaagag ggcaaagagt     4500

ggttgcgttc tcattctact ggagggcttc aggacactgg caaccagtca cctctggttt     4560

ccccttctgc catgtcatct tctgcagctg gaaaatacca cttttctaac ttggtgagcc     4620

caacaaattt gtctcagttt aaccttcccg ggcccagcat gatgcgctca aacagcatcc     4680

cagcccaaga ctcttccttc gatctctatg atgactccca gctttgtggg agtgccactt     4740

ctctggagga aagacctcgt gccatcagtc attcgggctc attcagagac agcatggaag     4800

aagttcatgg ctcttcatta tcactggtgt ccagcacttc ttctctttac tctacagctg     4860

aagaaaaggc tcattcagag caaatccata aactgcggag agagctggtt gcatcacaag     4920

aaaaagttgc taccctcaca tctcagcttt cagcaaatgc tcaccttgta gcagcttttg     4980

aaaagagctt agggaatatg actggccgat tgcaaagtct aactatgaca gcggaacaaa     5040

aggaatctga acttatagaa ctaagagaaa ccattgaaat gctgaaggct cagaattctg     5100

ctgcccaggc ggctattcag ggagcactga atggtccaga ccatcctccc aaagatcttc     5160

gcatcagaag acagcattcc tctgaaagtg tttctagtat caacagtgcc acaagccatt     5220

ccagtattgg cagtggtaat gatgccgact ccaagaagaa gaaaaagaaa aactgggtga     5280

actctagagg aagtgagctg agaagttctt tcaaacaagc ctttgggaag aaaaagtcca     5340

ccaagcctcc ttcatcacat tctgacattg aagagcttac tgattcatcc cttccggcat     5400

cccccaagtt accccataat gctggtgact gtggctcagc atccatgaag ccctcacaat     5460

ctgcttcagc gatctgtgaa tgcacagaag ctgaggcaga gataattctg cagctgaaga     5520

gcgagctcag agaaaaggaa ttaaaattaa cggatattcg gctggaggcc ctcagctctg     5580

ctcatcatct tgatcagatc cgggaagcca tgaaccggat gcagaatgaa attgaaatac     5640

tgaaagctga aaatgaccgg ttgaaggcag aaactggtaa cacagctaag cctactcggc     5700

caccgtcaga atcctcaagc agcacctcct cttcatcttc caggcagtca ttaggacttt     5760

ctctaaacaa tttgaacatc acagaggctg ttagctcaga tattttgcta gatgatgctg     5820

gtgatgcaac tggacataaa gatggccgca gtgtgaaaat tatagtctcc ataagcaagg     5880

gctatggtcg agcaaaggac caaaaatctc aggcatattt gataggatcc attggtgtta     5940

gtggaaaaac caagtgggat gtcttagatg gtgtaataag acgtctcttt aaggaatatg     6000

tattccgaat tgatacatcc actagccttg gtctgagctc tgactgcatt gctagctact     6060

gtataggaga cttaattaga tcccataacc tagaagtgcc tgaattgctg ccttgtggat     6120

accttgttgg agataataac atcatcactg tgaacctcaa aggggtagaa gaaaatagtt     6180

tggacagttt tgtttttgat acgctgattc ctaaaccaat tacccaaagg tactttaact     6240

tgttgatgga gcatcacaga attatactct caggaccgag tggtactgga aagacctatt     6300

tggcaaacaa acttgctgaa tatgtaataa ccaaatctgg aaggaaaaaa acagaggatg     6360

caattgccac ttttaatgtg gaccacaagt caagtaagga attgcaacaa tatctagcta     6420

acctggctga acagtgcagt gctgataata atggagtgga gctcccagtt gtaataattc     6480

ttgataatct tcatcatgtg ggctctctga gtgatatctt caatggtttt ctcaattgta     6540

aatacaacaa atgtccatat attattggaa caatgaatca gggagtttct tcatcaccaa     6600

atctagagct gcatcacaat ttcaggtggg tattatgtgc aaatcataca gaaccagtga     6660

aaggcttttt aggcagatat cttcgaagaa aactcataga gatagaaatt gaaaggaaca     6720

ttcgcaataa tgacctagtc aaaattatag attggattcc gaagacgtgg catcatctca     6780

acagtttttt ggaaacacac agttcttctg acgttaccat tggtccccga ctattccttc     6840

cttgccccat ggatgtagaa ggttctagag tatggttcat ggatctctgg aactattctt     6900

tagtacctta tattctggag gcagtgagag agggtcttca gatgtatggg aaacgcacac     6960

catgggaaga tccttcaaag tgggtgcttg acacatatcc atggagctca gcaactctgc     7020

ctcaggagag cccagcctta cttcagctgc gaccagaaga tgttgggtat gaaagctgca     7080

catccactaa ggaagccaca acctcaaagc acattccgca aactgacaca gaaggagatc     7140

ccctgatgaa tatgctaatg aaactccaag aagcagccaa ttactcgagc acacaaagct     7200

gcgacagcga aagcaccagc caccatgaag acattttgga ttcatctctt gaatctaccc     7260

tctagagggt gaaaaaagtt aagggaaaag actttgcttt taaaaaaatg tttcaaaaga     7320

aaggtatttt cactaaacca ctgccagtat aaaagcaccc tgtcaagggc cctgacccag     7380

agttgtggtc tccaaggagg cagcagaact aagtctgaac cgccaagatg ctaaattgca     7440

atggaagctt aactttagtt tatttctaag cattttttat atctgtggag taatagaaag     7500

ctccattact caactggaaa ggaccctaat gacagggcaa ctgaacagat tgcacatggg     7560

atagccaaac tggactttct ttgtttcctc tttaaaagtt tacaatgcag accatttttt     7620

gtcccttcct tttgtttcct ctgaggggct gttcgcccca ggcagggtcc atctttctga     7680

tctgtccaac ctcctttgtg ccacacggtg ctggtcacag ggcttcagta gtgtttgtgt     7740

tgtgcgctca ccccattcca gaacaaatcc aagaggccag tcctccataa gcacaaatgg     7800

aattgtgcaa ccaccagaaa aacactactg tggcaaactg gagaagtgcc aatttaattc     7860

taactgccac gttctcatga tgtgctccac caacttttta gtatatgagt cactggtttt     7920

ataaggttgt ttttaccaca gtggtctttt taaaccacct gcccactccc ttaacaagag     7980

ttttatacca attattagtc aacactgata aaaggctttt ttagggcttt atttgtttga     8040

gccttttcag tgaaagaagg aacatttcct atggtgctgt ctcactgcct taaaacagat     8100

ttctatgaca gtttaacagt tggtttaaat cctaaaccat tggtaatttc cactgtcttt     8160

tcatttacaa ccaagcaaca ccagttaaca tagtagcctc atctctatat atctttctct     8220

tttttttttt tttgaagaaa tggataggag aaagatcagt atttttagcc ttgtgaatag     8280

atcgctttgc ctatcctcca aaatattaaa ataacccaga aatgctcttt gaccgtcact     8340

taaaacctaa gacatgtggc gaaattccat ccagttctaa gtgaaagagt ttcagaaggc     8400

agaagatttt gaattattat ccagcagggc tggaagcact agatgcagca tgagcacaac     8460

tattcggctt tccttcccta ttgtttttgt ttttttaatg agttttgacg catgttgttt     8520

tgattgctat tgttgtacat gagaaattca gcattaaaga acactgaagc ggtaaggtca     8580

ctgtggaaga ggaagcgttt atactgtaaa agaaggttag atttgcacag tctactgggt     8640

aggtattgta aataataatt tttaaaactt gcacaaatca aaacaaacac aaacaaaatt     8700

gtattttatc ctgttggtgt taagaggtgt ttcacttgct gagatttcct gtacattgca     8760

aacaaataca gaatgcaaac cctcaaagct gtattatctg gtgtgtttgt cctgtattta     8820

cagttgtttt tgactatgca ggagctatca gtgctagagt gagcatgctt caaaactgta     8880

catgaagcca atatattttt ggataagtaa aactgtctga aagtacatct gtcatggcag     8940

gctttaaaga gagtgcatga aaactgatca gtcattggag aagttaccac cacacacaaa     9000

ggacaggttt taagtttatg aaacccaagg gctaggccat ggtatagact tcttctatga     9060

gtgtgtgaaa atgtgttact tttaggacgt gtatttggtg ctactctctg tgaccaccaa     9120

tgggtcagtt gctatagaac aacaacacca cgaaacatct gtgcagtttt cagagtgtca     9180

caaagtcaat aggtccttac acggtgctat tgccctaagg gaaatccgaa ctgaatttat     9240

gcacatagaa ttgtcaccct gactttgaag cctcaaacat ggatcaaatc tgttgtgaaa     9300

catcaatata tgtagctgga tgagtgacta gtttcccttg tataatatgt gatctaagaa     9360

aattgctaat ctttccctgc cattttgaga aacacagtcc aaacatgagc ataaacagaa     9420

tttcctgcaa tacatcccag taggtccacc tagtttacaa cttaaactag tttgtgaaac     9480

atttgtctgt atacatttta tattttgtac attttgatgt aacatatcat gtaaataggc     9540

agaaacagtg aaataaatca tctgaaaagt tttgtagtct ttgtaaagcc ccaacaataa     9600

gtacttggtg tcaatggact taactggatg atgtattttc tattggttta ttgttcctct     9660

agcttgtaaa ccagcttgca tatatttttt tgcaaatgtg caccctgtat ctgtctaaat     9720

tattactttg ccattaaagt ggaattattt attgacaaca aaaaaaaaaa aaaa           9774


<210>  1360
<211>  3735
<212>  DNA
<213>  homo sapiens

<400>  1360
agtcacaact tcgggggttg aggttgtcaa ggagctgtcc gtgatggttc tatggtgtgt       60

gcgtacacac atactctctc tctcacacac acacaccaca gtgacagatg acctattgaa      120

ataatttcag agccggtctg tggttgctac gacaaccaat gatctcttgg ctttcatctg      180

gccatgtgac agggactttg acgtcagcta gaggcagagt ctgtggctga gtccacacag      240

tcaaaggctt gtgagaatct ggtggatgct ggaccttgct gctgctgcta ctgctgtttc      300

caggggctgc agagcatgga ctgttaaatc ttgcacttct tctgagtgag ctgaattctt      360

gccgccagga tggggaaaca gaacagcaag ctgcgcccgg aggtcatgca ggacttgctg      420

gaaagcacag actttacaga gcatgagatc caggaatggt ataaaggctt cttgagagac      480

tgccccagtg gacatttgtc aatggaagag tttaagaaaa tatatgggaa ctttttccct      540

tatggggatg cttccaaatt tgcagagcat gtcttccgca ccttcgatgc aaatggagat      600

gggacaatag actttagaga attcatcatc gccttgagtg taacttcgag ggggaagctg      660

gagcagaagc tgaaatgggc cttcagcatg tacgacctgg acggaaatgg ctatatcagc      720

aaggcagaga tgctagagat cgtgcaggca atctataaga tggtttcctc tgtaatgaaa      780

atgcctgaag atgagtcaac cccagagaaa agaacagaaa agatcttccg ccagatggac      840

accaatagag acggaaaact ctccctggaa gagttcatcc gaggagccaa aagcgacccg      900

tccattgtgc gcctcctgca gtgcgacccg agcagtgccg gccagttctg agccctgcgc      960

ccaccaatcg aattgtagag ctgcttgtgt tcccttttga ttcttctttt taacaatttt     1020

tttttttttt tgccaaacaa tatcaatggt gatgccgtcc cctgtgcggt ctgatgcgcc     1080

ttcctccgtg acgccttcag cttcttttgt cgtggatgct tcgtgggaat gcccagagcc     1140

ccagtgtgct tgtggagagc atggacagac ttcgtggtgt tcattgtttg atgattttta     1200

atcgttacta ttattttttt ttattctaat gtctctgttc taaaacgtaa gactcggggg     1260

ttggggcaaa agaagggaaa cccatccagt cctgtgattc tattgcaagc ttcaaggggc     1320

ttttgtttga aagacaaaac tccccacctg aatctgttgt cacacgtgcc gtaggggtga     1380

tggatggcac cggatgctgg attccccaag aacaagttac cctctggggt gaggctattc     1440

cagcgagctg ggacatttcc ccatgggggc ccactcccct ctcttcccca gcaggctgta     1500

gtttctaagc tgtgaacatt tcaagataaa ttaacagagg agaggaaaaa gatggctcag     1560

ctattttttc acaggtttac actagttgag ctaatatgcg tgtctttgga aattaaacac     1620

aaatggtaac atattccaaa accagaccca tcttgttgcc tattgtgata aaataaaaag     1680

acggctgtat ataacatatt gggtaatgca gaccaaatta agtgttttgc cttgtttaaa     1740

tgaaatgcat gtttagtgag cactaataca atcttattcc agaagactgt ttttagtagc     1800

ttattgtgaa gtaagacaac tataatgaat gtctgtcttg tttggaagtc atatctgtct     1860

ttgcacaaat gtaccaatcg acaagtatat tttatatatt ccataaaaat acaaagtaac     1920

cctgactagg gcccaacttt aattttgaat gcatttccag agtggccatg cctagagggc     1980

agatgcagag caggtggtag tgggacagga caattggagc acaggaatgt taacatgtat     2040

gacaggggac cagtagggtg gtttccctct caggcccagc agcccattga cagcattaga     2100

ctggcggcat ggtgcttttc tgagcagatc aatactctgc agactcgaaa aaacatcaca     2160

tacattcttg gaacttccca gtggtttaat ctatgtgcat ggttagggag ccaggtctgg     2220

aatattcagt ttccctgccc ctgttaaaga atcagaggtt gggcagtcat caaattcatc     2280

ataaagacat gggcaagtgt gtctgtggtt tccaaggccc ccctatggag aatccaaaag     2340

tattttccat tgccgtgctc tttgaatgca gacttctatt tccagaagtg acagcacaag     2400

tctgagttgc tgtttggtct ggtgacctca gacacactaa tttgaattga aagctaagag     2460

taaaaatttg ctggttacag gcgagtcata ctcttgcaag tagttagcaa agggaggccc     2520

aaattctcaa ggttgttgat ggggaacttg ccactaagag aaggcagaga ggtccctagt     2580

gggtatattt gctgccaagc cacttgccaa agaagaggaa ccacagaaag agagacatca     2640

tgaccaggag aaaaatgtga ctagacatgc taacctccag gtttttatat atgacttgag     2700

tctgctgtaa ttggcagcag aaatccaaat ttgtatggta gaccaaaaag aaccaaatcc     2760

atagggtgaa attttgagac ctagactctg taaaaataat cctagtcttc ctccaggggt     2820

cagttcctca cagtggttct gtaccaaaac ttgccaaatt cctccatggc caagtgttaa     2880

aatctgtgtt tggaaaatag cgaattaacc taagacacag aaggcagact gggtgaggag     2940

acctagcatg ccctattggc agtgctcagg agctgcatcc cacttttccc tgctctgaat     3000

cgaagtccta gttccttcct ttgattctcc tttggtaggt ggaatcagtt aatgttttga     3060

gaaacctgcc tgggctctgc ccttagtcat gacatctcgc tgagccagac ccactctgtt     3120

ccttggaacc tagagctgga gtgaggagta gaggtctccg gctattccag aaagaaaagt     3180

gagccacatg caggctgatg aatgccgaca cttccagaat gtatagaaat agtccctgtc     3240

ctggcctgcc actgaccctg tctgtatttt ctcggaggtt gtttttctcc ttctccttcc     3300

caggaaggtc tttgtatgtc gaatccagtg cactcaagtt tggccaaggg actccacagc     3360

acccagaaga ctgcatgcct caaggtttat gtcactcctc tgctgggctg ttcattgtca     3420

ttgctgtgtt cagggacctt tggaaataaa acctgttctg tcccaaataa aaccagcctg     3480

tgatgttcaa gggactggaa taaagtggct tacgacctga aggattctac agagtgctca     3540

actgttcata catcattcag agtgggaggg agctgggggt gctgtcccat cccatctgta     3600

tgcccacggt ggatttaata atatataatt tataaatcat agcctatgga gtggcccgta     3660

aatcagttga ctgtgtagct cttgcctggc attaaagcat gtttttggtt taacatgaaa     3720

aaaaaaaaaa aaaaa                                                      3735


<210>  1361
<211>  3760
<212>  DNA
<213>  homo sapiens

<400>  1361
gacggtgctg tccaggggga ggcgggcgga gggaaggcgc tgccgctgct gccgccgcct       60

cgcccgaagc gacacagacg ctgggagcgg ccgaggcgag atcctatcat tattttaaaa      120

ttcctcctcc tccacgaagt ccttcctgat tccttcaaag aaatatcact cctccgaatt      180

cccagagtga tttcttctga cttgagcctg cagtgtgctg tgagagatct accactagat      240

tatctcaact ttggtctcct gggaccactc gttgctgaca gtcagaaatt gcagggcatc      300

tgatctcctg gtgttaaaat ctgtcgtgat accgaggaag gccccgagat cccaggcact      360

gagtgactgc atactctgaa ttcttgccgc caggatgggg aaacagaaca gcaagctgcg      420

cccggaggtc atgcaggact tgctggaaag cacagacttt acagagcatg agatccagga      480

atggtataaa ggcttcttga gagactgccc cagtggacat ttgtcaatgg aagagtttaa      540

gaaaatatat gggaactttt tcccttatgg ggatgcttcc aaatttgcag agcatgtctt      600

ccgcaccttc gatgcaaatg gagatgggac aatagacttt agagaattca tcatcgcctt      660

gagtgtaact tcgaggggga agctggagca gaagctgaaa tgggccttca gcatgtacga      720

cctggacgga aatggctata tcagcaaggc agagatgcta gagatcgtgc aggcaatcta      780

taagatggtt tcctctgtaa tgaaaatgcc tgaagatgag tcaaccccag agaaaagaac      840

agaaaagatc ttccgccaga tggacaccaa tagagacgga aaactctccc tggaagagtt      900

catccgagga gccaaaagcg acccgtccat tgtgcgcctc ctgcagtgcg acccgagcag      960

tgccggccag ttctgagccc tgcgcccacc aatcgaattg tagagctgct tgtgttccct     1020

tttgattctt ctttttaaca attttttttt ttttttgcca aacaatatca atggtgatgc     1080

cgtcccctgt gcggtctgat gcgccttcct ccgtgacgcc ttcagcttct tttgtcgtgg     1140

atgcttcgtg ggaatgccca gagccccagt gtgcttgtgg agagcatgga cagacttcgt     1200

ggtgttcatt gtttgatgat ttttaatcgt tactattatt tttttttatt ctaatgtctc     1260

tgttctaaaa cgtaagactc gggggttggg gcaaaagaag ggaaacccat ccagtcctgt     1320

gattctattg caagcttcaa ggggcttttg tttgaaagac aaaactcccc acctgaatct     1380

gttgtcacac gtgccgtagg ggtgatggat ggcaccggat gctggattcc ccaagaacaa     1440

gttaccctct ggggtgaggc tattccagcg agctgggaca tttccccatg ggggcccact     1500

cccctctctt ccccagcagg ctgtagtttc taagctgtga acatttcaag ataaattaac     1560

agaggagagg aaaaagatgg ctcagctatt ttttcacagg tttacactag ttgagctaat     1620

atgcgtgtct ttggaaatta aacacaaatg gtaacatatt ccaaaaccag acccatcttg     1680

ttgcctattg tgataaaata aaaagacggc tgtatataac atattgggta atgcagacca     1740

aattaagtgt tttgccttgt ttaaatgaaa tgcatgttta gtgagcacta atacaatctt     1800

attccagaag actgttttta gtagcttatt gtgaagtaag acaactataa tgaatgtctg     1860

tcttgtttgg aagtcatatc tgtctttgca caaatgtacc aatcgacaag tatattttat     1920

atattccata aaaatacaaa gtaaccctga ctagggccca actttaattt tgaatgcatt     1980

tccagagtgg ccatgcctag agggcagatg cagagcaggt ggtagtggga caggacaatt     2040

ggagcacagg aatgttaaca tgtatgacag gggaccagta gggtggtttc cctctcaggc     2100

ccagcagccc attgacagca ttagactggc ggcatggtgc ttttctgagc agatcaatac     2160

tctgcagact cgaaaaaaca tcacatacat tcttggaact tcccagtggt ttaatctatg     2220

tgcatggtta gggagccagg tctggaatat tcagtttccc tgcccctgtt aaagaatcag     2280

aggttgggca gtcatcaaat tcatcataaa gacatgggca agtgtgtctg tggtttccaa     2340

ggccccccta tggagaatcc aaaagtattt tccattgccg tgctctttga atgcagactt     2400

ctatttccag aagtgacagc acaagtctga gttgctgttt ggtctggtga cctcagacac     2460

actaatttga attgaaagct aagagtaaaa atttgctggt tacaggcgag tcatactctt     2520

gcaagtagtt agcaaaggga ggcccaaatt ctcaaggttg ttgatgggga acttgccact     2580

aagagaaggc agagaggtcc ctagtgggta tatttgctgc caagccactt gccaaagaag     2640

aggaaccaca gaaagagaga catcatgacc aggagaaaaa tgtgactaga catgctaacc     2700

tccaggtttt tatatatgac ttgagtctgc tgtaattggc agcagaaatc caaatttgta     2760

tggtagacca aaaagaacca aatccatagg gtgaaatttt gagacctaga ctctgtaaaa     2820

ataatcctag tcttcctcca ggggtcagtt cctcacagtg gttctgtacc aaaacttgcc     2880

aaattcctcc atggccaagt gttaaaatct gtgtttggaa aatagcgaat taacctaaga     2940

cacagaaggc agactgggtg aggagaccta gcatgcccta ttggcagtgc tcaggagctg     3000

catcccactt ttccctgctc tgaatcgaag tcctagttcc ttcctttgat tctcctttgg     3060

taggtggaat cagttaatgt tttgagaaac ctgcctgggc tctgccctta gtcatgacat     3120

ctcgctgagc cagacccact ctgttccttg gaacctagag ctggagtgag gagtagaggt     3180

ctccggctat tccagaaaga aaagtgagcc acatgcaggc tgatgaatgc cgacacttcc     3240

agaatgtata gaaatagtcc ctgtcctggc ctgccactga ccctgtctgt attttctcgg     3300

aggttgtttt tctccttctc cttcccagga aggtctttgt atgtcgaatc cagtgcactc     3360

aagtttggcc aagggactcc acagcaccca gaagactgca tgcctcaagg tttatgtcac     3420

tcctctgctg ggctgttcat tgtcattgct gtgttcaggg acctttggaa ataaaacctg     3480

ttctgtccca aataaaacca gcctgtgatg ttcaagggac tggaataaag tggcttacga     3540

cctgaaggat tctacagagt gctcaactgt tcatacatca ttcagagtgg gagggagctg     3600

ggggtgctgt cccatcccat ctgtatgccc acggtggatt taataatata taatttataa     3660

atcatagcct atggagtggc ccgtaaatca gttgactgtg tagctcttgc ctggcattaa     3720

agcatgtttt tggtttaaca tgaaaaaaaa aaaaaaaaaa                           3760


<210>  1362
<211>  3673
<212>  DNA
<213>  homo sapiens

<400>  1362
gacggtgctg tccaggggga ggcgggcgga gggaaggcgc tgccgctgct gccgccgcct       60

cgcccgaagc gacacagacg ctgggagcgg ccgaggcgag atcctatcat tattttaaaa      120

ttcctcctcc tccacgaagt ccttcctgat tccttcaaag aaatatcact cctccgaatt      180

cccagagtga tttcttctga cttgagcctg cagtgtgctg tgagagatct accactagat      240

tatctcaact ttggtctcct gggaccactc gttgctgaca gtcagaaact gaattcttgc      300

cgccaggatg gggaaacaga acagcaagct gcgcccggag gtcatgcagg acttgctgga      360

aagcacagac tttacagagc atgagatcca ggaatggtat aaaggcttct tgagagactg      420

ccccagtgga catttgtcaa tggaagagtt taagaaaata tatgggaact ttttccctta      480

tggggatgct tccaaatttg cagagcatgt cttccgcacc ttcgatgcaa atggagatgg      540

gacaatagac tttagagaat tcatcatcgc cttgagtgta acttcgaggg ggaagctgga      600

gcagaagctg aaatgggcct tcagcatgta cgacctggac ggaaatggct atatcagcaa      660

ggcagagatg ctagagatcg tgcaggcaat ctataagatg gtttcctctg taatgaaaat      720

gcctgaagat gagtcaaccc cagagaaaag aacagaaaag atcttccgcc agatggacac      780

caatagagac ggaaaactct ccctggaaga gttcatccga ggagccaaaa gcgacccgtc      840

cattgtgcgc ctcctgcagt gcgacccgag cagtgccggc cagttctgag ccctgcgccc      900

accaatcgaa ttgtagagct gcttgtgttc ccttttgatt cttcttttta acaatttttt      960

tttttttttg ccaaacaata tcaatggtga tgccgtcccc tgtgcggtct gatgcgcctt     1020

cctccgtgac gccttcagct tcttttgtcg tggatgcttc gtgggaatgc ccagagcccc     1080

agtgtgcttg tggagagcat ggacagactt cgtggtgttc attgtttgat gatttttaat     1140

cgttactatt attttttttt attctaatgt ctctgttcta aaacgtaaga ctcgggggtt     1200

ggggcaaaag aagggaaacc catccagtcc tgtgattcta ttgcaagctt caaggggctt     1260

ttgtttgaaa gacaaaactc cccacctgaa tctgttgtca cacgtgccgt aggggtgatg     1320

gatggcaccg gatgctggat tccccaagaa caagttaccc tctggggtga ggctattcca     1380

gcgagctggg acatttcccc atgggggccc actcccctct cttccccagc aggctgtagt     1440

ttctaagctg tgaacatttc aagataaatt aacagaggag aggaaaaaga tggctcagct     1500

attttttcac aggtttacac tagttgagct aatatgcgtg tctttggaaa ttaaacacaa     1560

atggtaacat attccaaaac cagacccatc ttgttgccta ttgtgataaa ataaaaagac     1620

ggctgtatat aacatattgg gtaatgcaga ccaaattaag tgttttgcct tgtttaaatg     1680

aaatgcatgt ttagtgagca ctaatacaat cttattccag aagactgttt ttagtagctt     1740

attgtgaagt aagacaacta taatgaatgt ctgtcttgtt tggaagtcat atctgtcttt     1800

gcacaaatgt accaatcgac aagtatattt tatatattcc ataaaaatac aaagtaaccc     1860

tgactagggc ccaactttaa ttttgaatgc atttccagag tggccatgcc tagagggcag     1920

atgcagagca ggtggtagtg ggacaggaca attggagcac aggaatgtta acatgtatga     1980

caggggacca gtagggtggt ttccctctca ggcccagcag cccattgaca gcattagact     2040

ggcggcatgg tgcttttctg agcagatcaa tactctgcag actcgaaaaa acatcacata     2100

cattcttgga acttcccagt ggtttaatct atgtgcatgg ttagggagcc aggtctggaa     2160

tattcagttt ccctgcccct gttaaagaat cagaggttgg gcagtcatca aattcatcat     2220

aaagacatgg gcaagtgtgt ctgtggtttc caaggccccc ctatggagaa tccaaaagta     2280

ttttccattg ccgtgctctt tgaatgcaga cttctatttc cagaagtgac agcacaagtc     2340

tgagttgctg tttggtctgg tgacctcaga cacactaatt tgaattgaaa gctaagagta     2400

aaaatttgct ggttacaggc gagtcatact cttgcaagta gttagcaaag ggaggcccaa     2460

attctcaagg ttgttgatgg ggaacttgcc actaagagaa ggcagagagg tccctagtgg     2520

gtatatttgc tgccaagcca cttgccaaag aagaggaacc acagaaagag agacatcatg     2580

accaggagaa aaatgtgact agacatgcta acctccaggt ttttatatat gacttgagtc     2640

tgctgtaatt ggcagcagaa atccaaattt gtatggtaga ccaaaaagaa ccaaatccat     2700

agggtgaaat tttgagacct agactctgta aaaataatcc tagtcttcct ccaggggtca     2760

gttcctcaca gtggttctgt accaaaactt gccaaattcc tccatggcca agtgttaaaa     2820

tctgtgtttg gaaaatagcg aattaaccta agacacagaa ggcagactgg gtgaggagac     2880

ctagcatgcc ctattggcag tgctcaggag ctgcatccca cttttccctg ctctgaatcg     2940

aagtcctagt tccttccttt gattctcctt tggtaggtgg aatcagttaa tgttttgaga     3000

aacctgcctg ggctctgccc ttagtcatga catctcgctg agccagaccc actctgttcc     3060

ttggaaccta gagctggagt gaggagtaga ggtctccggc tattccagaa agaaaagtga     3120

gccacatgca ggctgatgaa tgccgacact tccagaatgt atagaaatag tccctgtcct     3180

ggcctgccac tgaccctgtc tgtattttct cggaggttgt ttttctcctt ctccttccca     3240

ggaaggtctt tgtatgtcga atccagtgca ctcaagtttg gccaagggac tccacagcac     3300

ccagaagact gcatgcctca aggtttatgt cactcctctg ctgggctgtt cattgtcatt     3360

gctgtgttca gggacctttg gaaataaaac ctgttctgtc ccaaataaaa ccagcctgtg     3420

atgttcaagg gactggaata aagtggctta cgacctgaag gattctacag agtgctcaac     3480

tgttcataca tcattcagag tgggagggag ctgggggtgc tgtcccatcc catctgtatg     3540

cccacggtgg atttaataat atataattta taaatcatag cctatggagt ggcccgtaaa     3600

tcagttgact gtgtagctct tgcctggcat taaagcatgt ttttggttta acatgaaaaa     3660

aaaaaaaaaa aaa                                                        3673


<210>  1363
<211>  1703
<212>  DNA
<213>  homo sapiens

<400>  1363
gggcggagag ctggggccaa gtgcattgtg tctggcggcg gcgcgcgagc ccaccggcgg       60

ctgcggcggg gcgggaagcc atggagccgc gggcgctcgt cacggcgctc agcctcggcc      120

tcagcctgtg ctccctgggg ctgctcgtca cggccatctt caccgaccac tggtacgaga      180

ccgacccccg gcgccacaag gagagctgcg agcgcagccg cgcgggcgcc gaccccccgg      240

accagaagaa ccgcctgatg ccgctgtcgc acctgccgct gcgggactcg cccccgctgg      300

ggcgccggct gctcccgggc ggcccggggc gcgccgaccc cgagtcctgg cgctcgctcc      360

tggggctcgg cgggctggac gccgagtgcg gccggcccct cttcgccacc tactcgggcc      420

tctggaggaa gtgctacttc ctgggcatcg accgggacat cgacaccctc atcctgaaag      480

gtattgcgca gcgatgcacg gccatcaagt accacttttc tcagcccatc cgcttgcgaa      540

acattccttt taatttaacc aagaccatac agcaagatga gtggcacctg cttcatttaa      600

gaagaatcac tgctggcttc ctcggcatgg ccgtagccgt ccttctctgc ggctgcattg      660

tggccacagt cagtttcttc tgggaggaga gcttgaccca gcacgtggct ggactcctgt      720

tcctcatgac agggatattt tgcaccattt ccctctgtac ttatgccgcc agtatctcgt      780

atgatttgaa ccggctccca aagctaattt atagcctgcc tgctgatgtg gaacatggtt      840

acagctggtc catcttttgc gcctggtgca gtttaggctt tattgtggca gctggaggtc      900

tctgcatcgc ttatccgttt attagccgga ccaagattgc acagctaaag tctggcagag      960

actccacggt atgactgtcc tcactgggcc tgtccacagt gcgagcgact cctgagggga     1020

acagcgcgga gttcaggagt ccaagcacaa agcggtcttt tacattccaa cctgttgcct     1080

gccagccctt tctggattac tgatagaaaa tcatgcaaaa cctcccaacc tttctaagga     1140

caagactact gtggattcaa gtgctttaat gactatttat gcgttgactg tgagaatagg     1200

gagcagtgcc atgggacatt tctaggtgta gagaaagaag aaactgcaat ggaaaaattt     1260

gtatgatttc catttatttc agaaagtttg tatgtaacaa ttacccgaga gtcatttcta     1320

cttgcaaaag gattcgtaac aaagcgagta taattttctt gtcattgtat catgcttgtt     1380

aaattttaat gcagcatctt cagaacttgt cctgatggtg tcttattgtg tcagcaccaa     1440

atatttgtgc attatttgtg gacgttcctt gtcacaggaa gattcttctt ctgttgcctt     1500

attgtttttt tttttttaag tctcttctct gtctttgtac tggaatcgaa atcataagat     1560

aaacagatca aacgtgctta agagctaact cgtgacacta tgcagtattg tttgaagacc     1620

tgttgttcaa cctctgtctc tttatgttaa ctggatttct gcattaaatg actgccccct     1680

tgttaaaaaa aaaaaaaaaa aaa                                             1703


<210>  1364
<211>  1703
<212>  DNA
<213>  homo sapiens

<400>  1364
gggcggagag ctggggccaa gtgcattgtg tctggcggcg gcgcgcgagc ccaccggcgg       60

ctgcggcggg gcgggaagcc atggagccgc gggcgctcgt cacggcgctc agcctcggcc      120

tcagcctgtg ctccctgggg ctgctcgtca cggccatctt caccgaccac tggtacgaga      180

ccgacccccg gcgccacaag gagagctgcg agcgcagccg cgcgggcgcc gaccccccgg      240

accagaagaa ccgcctgatg ccgctgtcgc acctgccgct gcgggactcg cccccgctgg      300

ggcgccggct gctcccgggc ggcccggggc gcgccgaccc cgagtcctgg cgctcgctcc      360

tggggctcgg cgggctggac gccgagtgcg gccggcccct cttcgccacc tactcgggcc      420

tctggaggaa gtgctacttc ctgggcatcg accgggacat cgacaccctc atcctgaaag      480

gtattgcgca gcgatgcacg gccatcaagt accacttttc tcagcccatc cgcttgcgaa      540

acattccttt taatttaacc aagaccatac agcaagatga gtggcacctg cttcatttaa      600

gaagaatcac tgctggcttc ctcggcatgg ccgtagccgt ccttctctgc ggctgcattg      660

tggccacagt cagtttcttc tgggaggaga gcttgaccca gcacgtggct ggactcctgt      720

tcctcatgac agggatattt tgcaccattt ccctctgtac ttatgccgcc agtatctcgt      780

atgatttgaa ccggctccca aagctaattt atagcctgcc tgctgatgtg gaacatggtt      840

acagctggtc catcttttgc gcctggtgca gtttaggctt tattgtggca gctggaggtc      900

tctgcatcgc ttatccgttt attagccgga ccaagattgc acagctaaag tctggcagag      960

actccacggt atgactgtcc tcactgggcc tgtccacagt gcgagcgact cctgagggga     1020

acagcgcgga gttcaggagt ccaagcacaa agcggtcttt tacattccaa cctgttgcct     1080

gccagccctt tctggattac tgatagaaaa tcatgcaaaa cctcccaacc tttctaagga     1140

caagactact gtggattcaa gtgctttaat gactatttat gcgttgactg tgagaatagg     1200

gagcagtgcc atgggacatt tctaggtgta gagaaagaag aaactgcaat ggaaaaattt     1260

gtatgatttc catttatttc agaaagtttg tatgtaacaa ttacccgaga gtcatttcta     1320

cttgcaaaag gattcgtaac aaagcgagta taattttctt gtcattgtat catgcttgtt     1380

aaattttaat gcagcatctt cagaacttgt cctgatggtg tcttattgtg tcagcaccaa     1440

atatttgtgc attatttgtg gacgttcctt gtcacaggaa gattcttctt ctgttgcctt     1500

attgtttttt tttttttaag tctcttctct gtctttgtac tggaatcgaa atcataagat     1560

aaacagatca aacgtgctta agagctaact cgtgacacta tgcagtattg tttgaagacc     1620

tgttgttcaa cctctgtctc tttatgttaa ctggatttct gcattaaatg actgccccct     1680

tgttaaaaaa aaaaaaaaaa aaa                                             1703


<210>  1365
<211>  2667
<212>  DNA
<213>  homo sapiens

<400>  1365
acgtgagagg agacttccgg ccactgcgtt gtagtcggcc cggctgcaaa gcgtttttct       60

gcaggctgtt ttcccaggtt ccctcggcct gtacctcgcg cactcctctt gctccaggtc      120

cttcagtctc cgctcgtctc accgtaggct gtgacgacat gagcaacaaa gaaggatcag      180

gagggttcag gaaaaggaag catgacaatt tcccacataa ccaaagaaga gaagggaagg      240

atgttaattc atcttcaccc gtgatgttgg cctttaaatc atttcagcag gaacttgatg      300

caaggcatga caaatatgag agacttgtga aacttagtcg ggatataact gttgaaagta      360

aaaggacaat ttttctcctc cataggatta caagtgctcc tgatatggaa gatatattga      420

ctgaatcaga aattaaattg gatggtgtca gacaaaagat attccaggta gcccaagagc      480

tatcagggga agatatgcat cagttccatc gagccattac tacaggacta caggaatatg      540

tggaagctgt ctcttttcaa cacttcatca aaacacgatc attaattagt atggatgaaa      600

ttaataaaca attgatattt acgactgaag acaatgggaa agaaaataaa actccctcct      660

ctgatgcaca ggataagcag tttggtactt ggagactgag agtcacacct gtcgattacc      720

ttctgggagt ggctgactta actggagaat tgatgcggat gtgtattaac agtgtgggga      780

atggggacat tgataccccc tttgaagtga gccagttttt acgtcaggtt tatgatgggt      840

tttcattcat tggcaacact ggaccttacg aggtttctaa gaagctgtat accttgaaac      900

aaagtttggc caaagtggag aatgcttgtt atgccttgaa agtcagaggg tcagaaattc      960

caaaacatat gttggcagat gtgttttcag ttaaaacaga aatgatagat caagaagagg     1020

gcatttctta gaatctaacg ttactcagtt actaattctt ttgagaactc ctaagagacc     1080

aatttgtaag acttatttag tatttcattt aactttattg tggcttttac atagaaacat     1140

attcagttgt acttgtttta aattgtatac aagctgtaca taaaattagc caaatgaatc     1200

atttcttata tcttattcat gaaagtttgc atacagatgt ttgcatatat gcctttttga     1260

atttttgctg gttaaccttt atcatttatc tttgtaatgt gaacatgctt cagagtgtac     1320

cttttgccat aacctatttt aatttacttt ttctgaagtt tggagtgata atttttagtg     1380

gaagcaattt gtaatttaag ttggtagtta tattatatat agaaaagatt ttttagttaa     1440

acttctggac atgagcgtcc tgtttaaatt tcttgttaat atcgtgccaa gcctcaaaaa     1500

taggcttatt ccatggaaca agaattaaaa atgaataagc tatcaatata taatttaagt     1560

acaagtttag gctgggcgtg gtggctcacg cctgtaatcc cagcactttg ggaggccgag     1620

gtaggcagat cacgaggtca agagatcaag accagcctga ccaacgtggc gaaacctcgt     1680

ctctactaga aatacaaaaa ttagctggat atggtggtat gtgcctgtaa tcccagctac     1740

ttgggaggct gaggcaggag actcgcttga acctgggagg cagaggttgc agtgagccga     1800

gattgcgcca ctgcactcca gcctgggtaa cagagcaaga ctccatctca aaaaaagaaa     1860

gaaagaaaaa agaaagtaca agtttataaa gtattatagt gaaaaattcg cattctggct     1920

gattttaagc catttaaaat ttatataaaa caaccttcca taaaaatttg acaggtgccc     1980

agatgttgct ttctccattt attttttgtt tttttttaat cacagtaggt ctgatagaga     2040

attggagcta aattataata tttttgttgg taaagttgag ttatatactt gtacatacaa     2100

tggaaatgct tttagtagtg attatttagc aatttttgtt tttgttatat taggcatgtt     2160

tggaggcttt cctattctag catttaaatt taaattttat taaaattaaa taatttaaat     2220

ctagcattta aatttaaata atttaagtct agcatttact tttaaataat tataatgaag     2280

ttttgaaata ctaagttaat ccagaccttt agttgtccca tggtgttaat aaagttgcca     2340

aagaagatgt attatgaaca attcagcaat aagacaattg tcaacacagt tgagaataac     2400

aatggtaatc gttagtaata tttagaattg gaatttgcct actgaaatag ttatagatga     2460

ttacttgtga tgtgaaactg aattgagcat gacaaccaga catttccagt tggttttgta     2520

agttttgaga atctagatac tgggttttat tttttgaaag attagctctg tttgtaaggg     2580

ctgattcctt gaaaatgtaa ttttccagaa aaacacctaa agaaaataaa acatggacat     2640

gcctagtaaa aaaaaaaaaa aaaaaaa                                         2667


<210>  1366
<211>  2579
<212>  DNA
<213>  homo sapiens

<400>  1366
ggccctggct gccgccgctg cctcgtccgg actcggagag gacttgggag ggacagcggc       60

gctgggaggt ggcttagcag agactttcca gcaactgctg cccaggactt tttttttttt      120

ttttcttttt cccaggaggc ggcgacggcg gcggcggggg gagaggaaga gaaagaagcg      180

tctccagctg aagccaatgc agccctccgg ctctccgcga agaagttccc tgccccgatg      240

agcccccgcc gtgcgtcccc gactatcccc aggcgggcgt ggggcaccgg gcccagcgcc      300

gacgatcgct gccgttttgc ccttgggagt aggatgtggt gaaaggatgg ggcttctccc      360

ttacggggct cacaatggcc agagaagatt ccgtgaagtg tctgcgctgc ctgctctacg      420

ccctcaatct gctcttttgg ttaatgtcca tcagtgtgtt ggcagtttct gcttggatga      480

gggactacct aaataatgtt ctcactttaa ctgcagaaac gagggtagag gaagcagtca      540

ttttgactta ctttcctgtg gttcatccgg tcatgattgc tgtttgctgt ttccttatca      600

ttgtggggat gttaggatat tgtggaacgg tgaaaagaaa tctgttgctt cttgcatggt      660

actttggaag tttgcttgtc attttctgtg tagaactggc ttgtggcgtt tggacatatg      720

aacaggaact tatggttcca gtacaatggt cagatatggt cactttgaaa gccaggatga      780

caaattatgg attacctaga tatcggtggc ttactcatgc ttggaatttt tttcagagag      840

agtttaagtg ctgtggagta gtatatttca ctgactggtt ggaaatgaca gagatggact      900

ggcccccaga ttcctgctgt gttagagaat tcccaggatg ttccaaacag gcccaccagg      960

aagatctcag tgacctttat caagagggtt gtgggaagaa aatgtattcc tttttgagag     1020

gaaccaaaca actgcaggtg ctgaggtttc tgggaatctc cattggggtg acacaaatcc     1080

tggccatgat tctcaccatt actctgctct gggctctgta ttatgataga agggagccgg     1140

ggacagacca aatgatgtcc ttgaagaatg acaactctca gcacctgtca tgtccctcag     1200

tagaactgtt gaaaccaagc ctgtcaagaa tctttgaaca cacatccatg gcaaacagct     1260

ttaatacaca ctttgagatg gaggagttat aaaaagaaat gtcacagaag aaaaccacaa     1320

acttgtttta ctggacttgt gaatttttga gtacatacta tgtgtttcag aaatatgtag     1380

aaataaaaat gttgccataa aataacacct aagcatatac tattctatgc tttaaaatga     1440

ggatggaaaa gtttcatgtc ataagtcacc acctggacaa taattgatgc ccttaaaatg     1500

ctgaagacag atgtcatacc cactgtgtag cctgtgtatg acttttactg aacacagtta     1560

tgttttgagg cagcatggtt tgattagcat ttccgcatcc atgcaaacga gtcacatatg     1620

gtgggactgg agccatagta aaggttgatt tacttctacc aactagtata taaagtacta     1680

attaaatgct aacataggaa gttagaaaat actaataact tttattactc agcgatctat     1740

tcttctgatg ctaaataaat tatatatcag aaaactttca atattggtga ctacctaaat     1800

gtgatttttg ctggttacta aaatattctt accacttaaa agagcaagct aacacattgt     1860

cttaagctga tcagggattt tttgtatata agtctgtgtt aaatctgtat aattcagtcg     1920

atttcagttc tgataatgtt aagaataacc attatgaaaa ggaaaatttg tcctgtatag     1980

catcattatt tttagccttt cctgttaata aagctttact attctgtcct gggcttatat     2040

tacacatata actgttattt aaatacttaa ccactaattt tgaaaattac cagtgtgata     2100

cataggaatc attattcaga atgtagtctg gtctttagga agtattaata agaaaatttg     2160

cacataactt agttgattca gaaaggactt gtatgctgtt tttctcccaa atgaagactc     2220

tttttgacac taaacacttt ttaaaaagct tatctttgcc ttctccaaac aagaagcaat     2280

agtctccaag tcaatataaa ttctacagaa aatagtgttc tttttctcca gaaaaatgct     2340

tgtgagaatc attaaaacat gtgacaattt agagattctt tgttttattt cactgattaa     2400

tatactgtgg caaattacac agattattaa atttttttac aagagtatag tatatttatt     2460

tgaaatggga aaagtgcatt ttactgtatt ttgtgtattt tgtttatttc tcagaatatg     2520

gaaagaaaat taaaatgtgt caataaatat tttctagaga gtaaaaaaaa aaaaaaaaa      2579


<210>  1367
<211>  2579
<212>  DNA
<213>  homo sapiens

<400>  1367
ggccctggct gccgccgctg cctcgtccgg actcggagag gacttgggag ggacagcggc       60

gctgggaggt ggcttagcag agactttcca gcaactgctg cccaggactt tttttttttt      120

ttttcttttt cccaggaggc ggcgacggcg gcggcggggg gagaggaaga gaaagaagcg      180

tctccagctg aagccaatgc agccctccgg ctctccgcga agaagttccc tgccccgatg      240

agcccccgcc gtgcgtcccc gactatcccc aggcgggcgt ggggcaccgg gcccagcgcc      300

gacgatcgct gccgttttgc ccttgggagt aggatgtggt gaaaggatgg ggcttctccc      360

ttacggggct cacaatggcc agagaagatt ccgtgaagtg tctgcgctgc ctgctctacg      420

ccctcaatct gctcttttgg ttaatgtcca tcagtgtgtt ggcagtttct gcttggatga      480

gggactacct aaataatgtt ctcactttaa ctgcagaaac gagggtagag gaagcagtca      540

ttttgactta ctttcctgtg gttcatccgg tcatgattgc tgtttgctgt ttccttatca      600

ttgtggggat gttaggatat tgtggaacgg tgaaaagaaa tctgttgctt cttgcatggt      660

actttggaag tttgcttgtc attttctgtg tagaactggc ttgtggcgtt tggacatatg      720

aacaggaact tatggttcca gtacaatggt cagatatggt cactttgaaa gccaggatga      780

caaattatgg attacctaga tatcggtggc ttactcatgc ttggaatttt tttcagagag      840

agtttaagtg ctgtggagta gtatatttca ctgactggtt ggaaatgaca gagatggact      900

ggcccccaga ttcctgctgt gttagagaat tcccaggatg ttccaaacag gcccaccagg      960

aagatctcag tgacctttat caagagggtt gtgggaagaa aatgtattcc tttttgagag     1020

gaaccaaaca actgcaggtg ctgaggtttc tgggaatctc cattggggtg acacaaatcc     1080

tggccatgat tctcaccatt actctgctct gggctctgta ttatgataga agggagccgg     1140

ggacagacca aatgatgtcc ttgaagaatg acaactctca gcacctgtca tgtccctcag     1200

tagaactgtt gaaaccaagc ctgtcaagaa tctttgaaca cacatccatg gcaaacagct     1260

ttaatacaca ctttgagatg gaggagttat aaaaagaaat gtcacagaag aaaaccacaa     1320

acttgtttta ctggacttgt gaatttttga gtacatacta tgtgtttcag aaatatgtag     1380

aaataaaaat gttgccataa aataacacct aagcatatac tattctatgc tttaaaatga     1440

ggatggaaaa gtttcatgtc ataagtcacc acctggacaa taattgatgc ccttaaaatg     1500

ctgaagacag atgtcatacc cactgtgtag cctgtgtatg acttttactg aacacagtta     1560

tgttttgagg cagcatggtt tgattagcat ttccgcatcc atgcaaacga gtcacatatg     1620

gtgggactgg agccatagta aaggttgatt tacttctacc aactagtata taaagtacta     1680

attaaatgct aacataggaa gttagaaaat actaataact tttattactc agcgatctat     1740

tcttctgatg ctaaataaat tatatatcag aaaactttca atattggtga ctacctaaat     1800

gtgatttttg ctggttacta aaatattctt accacttaaa agagcaagct aacacattgt     1860

cttaagctga tcagggattt tttgtatata agtctgtgtt aaatctgtat aattcagtcg     1920

atttcagttc tgataatgtt aagaataacc attatgaaaa ggaaaatttg tcctgtatag     1980

catcattatt tttagccttt cctgttaata aagctttact attctgtcct gggcttatat     2040

tacacatata actgttattt aaatacttaa ccactaattt tgaaaattac cagtgtgata     2100

cataggaatc attattcaga atgtagtctg gtctttagga agtattaata agaaaatttg     2160

cacataactt agttgattca gaaaggactt gtatgctgtt tttctcccaa atgaagactc     2220

tttttgacac taaacacttt ttaaaaagct tatctttgcc ttctccaaac aagaagcaat     2280

agtctccaag tcaatataaa ttctacagaa aatagtgttc tttttctcca gaaaaatgct     2340

tgtgagaatc attaaaacat gtgacaattt agagattctt tgttttattt cactgattaa     2400

tatactgtgg caaattacac agattattaa atttttttac aagagtatag tatatttatt     2460

tgaaatggga aaagtgcatt ttactgtatt ttgtgtattt tgtttatttc tcagaatatg     2520

gaaagaaaat taaaatgtgt caataaatat tttctagaga gtaaaaaaaa aaaaaaaaa      2579


<210>  1368
<211>  1268
<212>  DNA
<213>  homo sapiens

<400>  1368
gccctctcac cccgctgcct ctaggttctg ggaagatggc gaaggtctca gagctttacg       60

atgtcacttg ggaagaaatg agagataaaa tgagaaaatg gagagaagaa aactcaagaa      120

atagtgagca aattgtggaa gttggagaag aattaattaa tgaatatgct tctaagctgg      180

gagatgatat ttggatcata tatgaacagg tgatgattgc agcactagac tatggtcggg      240

atgacttggc attgttttgt cttcaagagc tgagaagaca gttccctggc agtcacagag      300

tcaagcgatt aacaggcatg agatttgaag ccatggaaag atatgatgat gctatacagc      360

tatatgatag gattttacaa gaagatccaa ctaacactgc tgcaagaaag cgtaagattg      420

ccattcgaaa agcccagggg aaaaatgtgg aggccattcg ggagctgaat gagtatctgg      480

aacaatttgt tggagaccaa gaagcctggc atgaacttgc agaactttac atcaatgaac      540

atgactatgc aaaagcagcc ttttgtttag aggaactaat gatgactaat ccacacaacc      600

acttatactg tcagcagtat gctgaagtta agtataccca aggtggactt gaaaacctcg      660

aactttcaag aaagtatttt gcacaggcat tgaaactgaa caacagaaat atgagagctt      720

tgtttggact ttatatgtcg gcaagtcata ttgcttctaa tccaaaagca agtgcaaaaa      780

cgaaaaagga caacatgaaa tatgctagtt gggcagctag tcaaataaac agagcttatc      840

agtttgcagg tcgaagtaag aaggaaacca aatattctct taaggctgtc gaagacatgt      900

tggaaacatt gcagatcacc cagtcttaag gtttcaaaaa ctctttgaca ttagatttca      960

caactgcaca attgaactta ttggcctgta acttatttac taaatgctca gtgctattta     1020

tatactacag taattttctg ttaagaaggc agttgtaaag aatgtgttta tataaaccta     1080

aaaatgcctt ttactgctaa gtggggagat gggggaaatc catggaagag agatttaaga     1140

cttattgatt gtacatcagt ctcttcatat cacatataca tgtatatata taaaactcta     1200

atgtagtata accttgttaa ataaaccatg atgatttaca aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaa                                                              1268


<210>  1369
<211>  4304
<212>  DNA
<213>  homo sapiens

<400>  1369
cccgccccgt cgcactcaga gagctgggct ggagctccaa gcggaaaccg cgggagccga       60

gcccagctag gaatgcagac ctcctgaaaa ccaagccgag gactgcgggg tccggtgtcc      120

acgcagagtg tcagcttcct ctggtgcaac cagcaagtct tccagtatga atcccacaga      180

aaccaaggct gtaaaaacag aacctgagaa gaagtcacag tcaaccaagc tgtctgtggt      240

tcatgagaaa aaatcccaag aaggaaagcc aaaagaacac acagagccaa aaagcctacc      300

caagcaggca tcagatacag gaagtaacga tgctcacaat aaaaaagcag tttccagatc      360

agctgaacag cagccatcag agaaatcaac agaaccaaag actaaaccac aagacatgat      420

ttctgctggt ggagagagtg ttgctggtat cactgcaata tctggcaagc cgggtgacaa      480

gaaaaaagaa aagaaatcat taaccccagc tgtgccagtt gaatctaaac cggataaacc      540

atcgggaaag tcaggcatgg atgctgcttt ggatgactta atagatactt taggaggacc      600

tgaagaaact gaagaagaaa atacaacgta tactggacca gaagtttcag atccaatgag      660

ttccacctac atagaggaat tgggtaaaag agaagtcaca attcctccaa aatataggga      720

actattggct aaaaaggaag ggatcacagg gcctcctgca gactcttcga aacccatagg      780

gccagatgat gctatagacg ccttgtcatc tgacttcacc tgtgggtcgc ctacagctgc      840

tggaaagaaa actgaaaaag aggaatctac agaagtttta aaagctcagt cagcagggac      900

agtcagaagt gctgctccac cccaagagaa gaaaagaaag gtggagaagg atacaatgag      960

tgatcaagca ctcgaggctc tgtcggcttc actgggcacc cggcaagcag aacctgagct     1020

cgacctccgc tcaattaagg aagtcgatga ggcaaaagct aaagaagaaa aactagagaa     1080

gtgtggtgag gatgatgaaa caatcccatc tgagtacaga ttaaaaccag ccacggataa     1140

agatggaaaa ccactattgc cagagcctga agaaaaaccc aagcctcgga gtgaatcaga     1200

actcattgat gaactttcag aagattttga ccggtctgaa tgtaaagaga aaccatctaa     1260

gccaactgaa aagacagaag aatctaaggc cgctgctcca gctcctgtgt cggaggctgt     1320

gtgtcggacc tccatgtgta gtatacagtc agcaccccct gagccggcta ccttgaaggg     1380

cacagtgcca gatgatgctg tagaagcctt ggctgatagc ctggggaaaa aggaagcaga     1440

tccagaagat ggaaaacctg tgatggataa agtcaaggag aaggccaaag aagaagaccg     1500

tgaaaagctt ggtgaaaaag aagaaacaat tcctcctgat tatagattag aagaggtcaa     1560

ggataaagat ggaaagccac tcctgccaaa agagtctaag gaacagcttc cacccatgag     1620

tgaagacttc cttctggatg ctttgtctga ggacttctct ggtccacaaa atgcttcatc     1680

tcttaaattt gaagatgcta aacttgctgc tgccatctct gaagtggttt cccaaacccc     1740

agcttcaacg acccaagctg gagccccacc ccgtgatacc tcgcagagtg acaaagacct     1800

cgatgatgcc ttggataaac tctctgacag tctaggacaa aggcagcctg acccagatga     1860

gaacaaacca atggaagata aagtaaagga aaaagctaaa gctgaacata gagacaagct     1920

tggagaaaga gatgacacta tcccacctga atacagacat ctcctggatg ataatggaca     1980

ggacaaacca gtgaagccac ctacaaagaa atcagaggat tcaaagaaac ctgcagatga     2040

ccaagacccc attgatgctc tctcaggaga tctggacagc tgtccctcca ctacagaaac     2100

ctcacagaac acagcaaagg ataagtgcaa gaaggctgct tccagctcca aagcacctaa     2160

gaatggaggt aaagcgaagg attcagcaaa gacaacagag gaaacttcca agccaaaaga     2220

tgactaaaga aatacaagtt aaggtatctg gtatctgcat gtaaaatctt cagctggtgg     2280

atggtgactt ttgaagaaca aaaggctttg gcaacagaaa acaattgttc tgggtgattt     2340

ctagaatggt ttttgttgag tctctgaaca tcctaaatat tggtttgtta ttcttttcca     2400

gaaagaaaat gaatttgact ggttcacctg tgtactgagt attgataaac tttgaatttt     2460

tttaattgcc ttcaattggg agagaaagct ttatatttgt aagaaatata tttgataaag     2520

tttcttaaag caacaccaaa aaaacaaaag aaaagctaag tgaatttttg cacattctac     2580

acacagtgcc tgtaaatctc atttgtattt tcagtttgcc cttaattttt tttgttagtg     2640

tttagaaaac aatgttttaa acattcttca gtgttctgat ttcttattac cccctttcct     2700

cttgggcttt tgaactgtat ttgatgttgc tttgggataa tgtttataag tcaaacataa     2760

gatattgtac attgggcaca tatctcctct tgggctgcta ataataaatt aataacaggt     2820

aacctggaca aaccaggaag caccaaaccc cttttcagtt tgaactcttc tttgccaggt     2880

gtgaggactt ctgcatctta cagtcagcac agaacacact gagacttgaa tcaagtcagc     2940

aacagagcaa aataaaggtt agataagtcc ttgtgtagca aatttcgagc ataagaaata     3000

aaatctaatt aattcttagg gtactcatct gacttgaact ctgttggttt actgtgttag     3060

taaactgtgc tttctattat ctatacataa aacctgagca gcaactgtgt ctttagagct     3120

attgccacat tagcctttgc actgtatagc gtctggcttt atggaactta agtttaccaa     3180

atataaaaag aaacttctgc ttttaaaaaa attatatata tatattaaat ttgaaacctg     3240

catttctccc acagcaatgt aagaagtagg ctctgatgtc ctaccacttt gaatggtttt     3300

ctaatatctt aatgaatagt tcctgaacat tgcactgata tcatcgatta gaattttgat     3360

atttaatttc atctttattt cctggtagag aatgcaggaa aagatgtcag gtacataaca     3420

taaaacagat tgggaattta ttgtttccaa agggcatggc cttccttagc atcagtttga     3480

agcttttgtt atgacttagc tgacttgtgg cagcggggca agcaaaaaca ataacactgc     3540

ttataaatgg caccacatct tgttaacctc ccccccaaat actctctgaa agtcatgcac     3600

atacctatgg gattttacac accaccagct taaaatgcta tgtctctatc catcagaaat     3660

agtcattatt ctatttttaa ggcagcaaca agaaaagaaa aaacactttt cctgagggat     3720

ttctaaccat gtatctaatc ctcccatttg ggcagtatag gtgtttgctt ttttgttttc     3780

tttttttaag aaaaaccttg aaacctttga cactgacaga tgtgtttgca aggatacggc     3840

ttcagtatta ctaatttcca tgtgtatctg gaagtatttt taaatggcat accaaaatcc     3900

agaagtttaa agatgcctat aaaagtaaac aacatttatt taaaaagaac tctgaatatg     3960

ccttcttttt taattagaaa tatcttcgag acttgggtgt ttgttaataa ctaataactg     4020

gagtaagcta caggatctaa agcagccctt tttacagtct agttaggaga gagaaaataa     4080

ttgcaaatat ccacttagag gcaaagaaca attttttatt atcaaaaagg tttctgcaca     4140

ttgttgtggc aatattgtat ctgtttagaa aatgggcttt tccaaaagca aacaaagata     4200

ggttcctcag gtgaccaaaa ctgaaaatca atatttccat gtttcattaa tcaaggcata     4260

aaatacaatt aaagcaaaat attttacatt aaaaaaaaaa aaaa                      4304


<210>  1370
<211>  4305
<212>  DNA
<213>  homo sapiens

<400>  1370
agatgccgcc tggcaccaag cgcagccgcc gctgccgcac tttccacttg tattgatcac       60

ctctcagccc cgcgcagccg gctcgcccga gcggaccgcg gccagcgcgc cagcccttgg      120

cagccccgga gcagtcgggc tccgggagga aactccttgg gagcgccctg tccggggtgc      180

cctctgcgct ctgcagtgtc tttctttctg cctgggagga ggaggaggag gaggaagagg      240

aggaggagga ggaggaggag gaggaagagg aggaggagga ggaggacgtc tggtcccggc      300

tgggaggtgg agcagcggca gcagcagcag ccgccgccgc cgccgccgct gccgccgccg      360

ccggaaaggg agaggcagga gagcccgaga cttggaaacc ccaaagtgtc cgcgaccctg      420

cacggcaggc tcccttccag cttcatgggc aaagtgtgga aacagcagat gtaccctcag      480

tacgccacct actattaccc ccagtatctg caagccaagc agtctctggt cccagcccac      540

cccatggccc ctcccagtcc cagcaccacc agcagtaata acaacagtag cagcagtagc      600

aactcaggat gggatcagct cagcaaaacg aacctctata tccgaggact gcctccccac      660

accaccgacc aggacctggt gaagctctgt caaccatatg ggaaaatagt ctccacaaag      720

gcaattttgg ataagacaac gaacaaatgc aaaggttatg gttttgtcga ctttgacagc      780

cctgcagcag ctcaaaaagc tgtgtctgcc ctgaaggcca gtggggttca agctcaaatg      840

gcaaagcaac aggaacaaga tcctaccaac ctctacattt ctaatttgcc actctccatg      900

gatgagcaag aactagaaaa tatgctcaaa ccatttggac aagttatttc tacaaggata      960

ctacgtgatt ccagtggtac aagtcgtggt gttggctttg ctaggatgga atcaacagaa     1020

aaatgtgaag ctgttattgg tcattttaat ggaaaattta ttaagacacc accaggagtt     1080

tctgccccca cagaaccttt attgtgtaag tttgctgatg gaggacagaa aaagagacag     1140

aacccaaaca aatacatccc taatggaaga ccatggcata gagaaggaga ggtgagactt     1200

gctggaatga cacttactta cgacccaact acagctgcta tacagaacgg attttatcct     1260

tcaccataca gtattgctac aaaccgaatg atcactcaaa cttctattac accctatatt     1320

gcatctcctg tatctgccta ccaggtgcaa agtccttcgt ggatgcaacc tcaaccatat     1380

attctacagc accctggtgc cgtgttaact ccctcaatgg agcacaccat gtcactacag     1440

cccgcatcaa tgatcagccc tctggcccag cagatgagtc atctgtcact aggcagcacc     1500

ggaacataca tgcctgcaac gtcagctatg caaggagcct acttgccaca gtatgcacat     1560

atgcagacga cagcggttcc tgttgaggag gcaagtggtc aacagcaggt ggctgtcgag     1620

acgtctaatg accattctcc atataccttt caacctaata agtaactgtg agatgtacag     1680

aaaggtgttc ttacatgaag aagggtgtga aggctgaaca atcatggatt tttctgatca     1740

attgtgcttt aggaaattat tgacagtttt gcacaggttc ttgaaaacgt tatttataat     1800

gaaatcaact aaaactattt ttgctataag ttctataagg tgcataaaac ccttaaattc     1860

atctagtagc tgttcccccg aacaggttta ttttagtaaa aaaaaaaaaa caaaaaacaa     1920

aaacaaaaga tttttatcaa atgttatgat gcaaaaaaag aaaaagaaaa aaaaaaagaa     1980

aagaaaactt caattttctg ggtatgcaca aagaccatga agacttatcc aagtgcatga     2040

ccggattttt gtggttttgt tcattttgtg tttaatttgt gttttttttt tccagctgta     2100

tgaaatgggc tttctgaagt ttaaatagtc cgacttcacc catggtgttc tgtgcttgca     2160

gtgcgagtgt tgctgtaatt cagtgttgcc gtcagtgtct cttttcttag ctttctgtct     2220

ttctttcaac gtagtgtgaa gtgtcttatc cttttctatg aattccaatt tgccttaact     2280

cttttgatgc tgtagctgtt tcagtaaaag ttagttcaaa ctaatgatgt agaatgcttt     2340

gaccaaatga gctggtctat tatgccttgt aaaacagcag catagggctt ttaaaaggta     2400

gtcaataaaa gttgctgaaa ttttggcttt tttaaatatg tagtaggtgt ttttaatgat     2460

ttttcacata atgtgtaagg tagtgaaatg caagaaggga aaaatgtttt gtgtgaaaca     2520

cattttctga ctggggaact tttattaggg taaattgttt gtaaggctgt acgccaacag     2580

tttcctctga tagtttgact gatttaggat atctgctgta tgatgcaatg taaagtcttt     2640

tttgcctttt ttcaggaaaa aaaaaaagct aacttgatgt actagattta gtgtaggtag     2700

tgttggggtt ggggatgggg gtgggggagg ggagtcactg aatgttttgt ccttccttta     2760

tactaatgat agtgctttag aatgagaatt atgcctgaaa tctggcaaac cgaaaaatgt     2820

tgctattgca acaaagtggc aaaagctaaa agtaaggatt tatcttcaaa cataagctga     2880

gataacgaat agaagcaaaa cgattggcta ctagctctct ctctctctct ctattaggta     2940

aatttgaaaa ataaaaatga cttggcactt ttaaaggtaa cttcaccaaa gaccgaagag     3000

ccagtaacca gtagctccaa cttgtctcag catcacatct tctgtgctct ttatttttgc     3060

cggaccagtt tgcggttagg agaatgtgcc ttttttgtac ctttgcattt aggttttata     3120

attttaattg atgtatggac acacacaaac aaaaaagcat gaaggaagat ttggatccaa     3180

gcagtgccac actttacatc atcactacaa gtgttcaagt gtaaagaaaa ccaattttga     3240

aactatgaaa ttcctgattc ataaatacac agttatttct actttagtac atataagata     3300

attcactgtt attaaagctc ttttattaag gcaattgcat atgttttaaa agcaatggta     3360

aattaagttg tcttccaaaa ctgtgtactt gtctggtcag ctgtgtatga tcagttatct     3420

acctcagagt ctattttctt ttgtgctggg acaggttgct ggccctccct gtttccacag     3480

accaaatcct cctagctcag gagctagggc taagcagtta tttctttcaa gtatttttta     3540

gttcttaaat tttatgcttg tatttgatga tagatgtcag tgacatttca tagtttcaaa     3600

agtccttgct gctctgagaa gtgtagattc tagtgaaaat tacatagtca taagagaaat     3660

gtgtttttgt ttttgttttt gtttcatttt tttaaagttg tggtattatt ggttctatgc     3720

tccctggaat attactgctt tgtgaaagtc cagactgaac gcagcaccct ctgtgtacct     3780

agtacagtta taaacctggg tctctcacta cttgatattt ttgcattagt taagacagaa     3840

atttgatagc tcggttagag gggaggggaa atctgctgct agaaatgtct gaactaagtg     3900

ccatactcgt ctgggtaaga tttgggaaac ataacctctg tacataaaaa aaaaaaaatc     3960

agttaaacat cacatagtag acagccatta aattataaaa aaattaattt atgaagaaag     4020

accttttgta cagattgaaa aaaaaagatt ttcatagaga tatctatatg atcaagagag     4080

ttaatttttt atttttgttt tactagtgcc acagacttgc cagtggtaac ttatttgtcc     4140

ggttcaagat aactctgtag ttttctttcc taggacttgt tgttaaacgc caaaagacat     4200

ttttgaactg tacatttgat cagattgtta gcttttctgt tttatttctt ttgagaacct     4260

ttgaataaaa aacatctgaa attttaaaaa aaaaaaaaaa aaaaa                     4305


<210>  1371
<211>  8378
<212>  DNA
<213>  homo sapiens

<400>  1371
gccatttcca gagaggaaca accgtgtaga ctgctttcct gggagtcaag ttaaaacttc       60

tctcctgtga ccttgtcacc cggcagtgga aagttaccct tggctgcagc cacgacttcc      120

gcatactctt cagaacttgc tctgcccttg agttttccag ctttccttta atgcactaaa      180

cctttaatat tgtattctcc taaatgagac gtctcgcatt tgagcaggga gagtcccgta      240

ttctcagagt aaaagttgtt tctggaattg atctcgccaa aaaggacatc tttggagcca      300

gtgatccgta tgtgaaactt tcattgtacg tagcggatga gaatagagaa cttgctttgg      360

tccagacaaa aacaattaaa aagacactga acccaaaatg gaatgaagaa ttttatttca      420

gggtaaaccc atctaatcac agactcctat ttgaagtatt tgacgaaaat agactgacac      480

gagacgactt cctgggccag gtggacgtgc cccttagtca ccttccgaca gaagatccaa      540

ccatggagcg accctataca tttaaggact ttctcctcag accaagaagt cataagtctc      600

gagttaaggg atttttgcga ttgaaaatgg cctatatgcc aaaaaatgga ggtcaagatg      660

aagaaaacag tgaccagagg gatgacatgg agcatggatg ggaagttgtt gactcaaatg      720

actcggcttc tcagcaccaa gaggaacttc ctcctcctcc tctgcctccc gggtgggaag      780

aaaaagtgga caatttaggc cgaacttact atgtcaacca caacaaccgg accactcagt      840

ggcacagacc aagcctgatg gacgtgtcct cggagtcgga caataacatc agacagatca      900

accaggaggc agcacaccgg cgcttccgct cccgcaggca catcagcgaa gacttggagc      960

ccgagccctc ggagggcggg gatgtccccg agccttggga gaccatttca gaggaagtga     1020

atatcgctgg agactctctc ggtctggctc tgcccccacc accggcctcc ccaggatctc     1080

ggaccagccc tcaggagctg tcagaggaac taagcagaag gcttcagatc actccagact     1140

ccaatgggga acagttcagc tctttgattc aaagagaacc ctcctcaagg ttgaggtcat     1200

gcagtgtcac cgacgcagtt gcagaacagg gccatctacc accgcccagt gccccagctg     1260

ggagagcgcg ttcatcaact gtcacgggtg gtgaggaacc aacgccatca gtggcctatg     1320

tacataccac gccgggtctg ccttcaggct gggaagaaag aaaagatgct aaggggcgca     1380

catactatgt caatcataac aatcgaacca caacttggac tcgacctatc atgcagcttg     1440

cagaagatgg tgcgtccgga tcagccacaa acagtaacaa ccatctaatc gagcctcaga     1500

tccgccggcc tcgtagcctc agctcgccaa cagtaacttt atctgccccg ctggagggtg     1560

ccaaggactc acccgtacgt cgggctgtga aagacaccct ttccaaccca cagtccccac     1620

agccatcacc ttacaactcc cccaaaccac aacacaaagt cacacagagc ttcttgccac     1680

ccggctggga aatgaggata gcgccaaacg gccggccctt cttcattgat cataacacaa     1740

agactacaac ctgggaagat ccacgtttga aatttccagt acatatgcgg tcaaagacat     1800

ctttaaaccc caatgacctt ggcccccttc ctcctggctg ggaagaaaga attcacttgg     1860

atggccgaac gttttatatt gatcataata gcaaaattac tcagtgggaa gacccaagac     1920

tgcagaaccc agctattact ggtccggctg tcccttactc cagagaattt aagcagaaat     1980

atgactactt caggaagaaa ttaaagaaac ctgctgatat ccccaatagg tttgaaatga     2040

aacttcacag aaataacata tttgaagagt cctatcggag aattatgtcc gtgaaaagac     2100

cagatgtcct aaaagctaga ctgtggattg agtttgaatc agagaaaggt cttgactatg     2160

ggggtgtggc cagagaatgg ttcttcttac tgtccaaaga gatgttcaac ccctactacg     2220

gcctctttga gtactctgcc acggacaact acacccttca gatcaaccct aattcaggcc     2280

tctgtaatga ggatcatttg tcctacttca cttttattgg aagagttgct ggtctggccg     2340

tatttcatgg gaagctctta gatggtttct tcattagacc attttacaag atgatgttgg     2400

gaaagcagat aaccctgaat gacatggaat ctgtggatag tgaatattac aactctttga     2460

aatggatcct ggagaatgac cctactgagc tggacctcat gttctgcata gacgaagaaa     2520

actttggaca gacatatcaa gtggatttga agcccaatgg gtcagaaata atggtcacaa     2580

atgaaaacaa aagggaatat atcgacttag tcatccagtg gagatttgtg aacagggtcc     2640

agaagcagat gaacgccttc ttggagggat tcacagaact acttcctatt gatttgatta     2700

aaatttttga tgaaaatgag ctggagttgc tcatgtgcgg cctcggtgat gtggatgtga     2760

atgactggag acagcattct atttacaaga acggctactg cccaaaccac cccgtcattc     2820

agtggttctg gaaggctgtg ctactcatgg acgccgaaaa gcgtatccgg ttactgcagt     2880

ttgtcacagg gacatcgcga gtacctatga atggatttgc cgaactttat ggttccaatg     2940

gtcctcagct gtttacaata gagcaatggg gcagtcctga gaaactgccc agagctcaca     3000

catgctttaa tcgccttgac ttacctccat atgaaacctt tgaagattta cgagagaaac     3060

ttctcatggc cgtggaaaat gctcaaggat ttgaaggggt ggattaagca ccctgtgcct     3120

cgggggtggt tgttcttcaa gcaagttctg cttgcacttt tgcatttgcc taacagactt     3180

ttgcagaggc gatggcagag agcagctgca ggcatggtcc ctggagccga gccttcacca     3240

cgcactcgtc caagttcgga tgcgggaacc tggtcccagc ttgagttcct gcctttccca     3300

ccacaaatta tcaactggtt gatgtgtaca ctaattacat ttcaggagga cttaatgcta     3360

tttatgttgt gcctctgcag gcaaagccct taataaatat tttacatcct ttctaatgac     3420

aatgaatgga attaatcact caacaggtat agtattacga ctcatgttta ctttttaaaa     3480

tgatttagac cgattttcag attttatttc gttatgatta aagatgtctc atgtacttgg     3540

aaaagtgagc attttttttt tttttgtatt tcactttcat accaggctta atgtcaatga     3600

catttttatt tttgaagtac tctgacacct ccaccctcta ctttattaga attggaaggc     3660

aaatttttgt ccaaaaacct acagacaagt actttgagag aatttccaat ataatattag     3720

acataatgat aattttttcc atactcagaa tgaaaaactg gatattacgt ttttgttttg     3780

gggttttttt gtacaaattt agctaatagc tacaggctga gagaattgta acatagcatg     3840

acaaattttg tgttgacttg aaaggaatca caccattatt ccttagaagt aattacatgt     3900

gttctaacac atttgagaca gggttggact cccatttctc atccgagaaa ttacttaacc     3960

cttcctggcg ctgtacagtc atcttttatt ctatttcctc tttgctgttt gtagtagaga     4020

cattttgaat gaaacttggc actgcttgat tcaaaactgt ggaaaccaga tctgtttagt     4080

ctcctgtttg tatgcgtttg ctaatggtag ctaaataacc agtttttgtt gtaaatgcac     4140

caattctgaa ggcactttat gtactacatg gaggtcatat ctggttttgt ttttattttt     4200

ttatcatgaa cattaaatgt gatgatgatt tcttttccct gcacacatct ttccggtgca     4260

atatctatca attgtgaatc tggctgctgg tgtataaaaa cctggatgta aagctgagcc     4320

tacagacctg tcctcaccaa ctgttttgtg atttctactc aactacaaag atttatttaa     4380

tgtactctta atctaactga gttttgttac caatgacctg ttgcatgctt caataccgtg     4440

tactgcctga gttgtgcctc ttgtgtgcta gattaaaagt gagacagaga cttgacttga     4500

tcctctgagc tcaagctatt gagctggtag tggcagagga ctgagggtac ctgcacagtt     4560

tgattctttt ccacgtgtaa gtctccattg cagaattgtc gtgctttgag aaaacacctg     4620

aggcagtgtg ggagttgaac gaccctgctg tcctttttaa cctgtgttgt cctagaccct     4680

gtcggggcag tcaggggaca ctagagattt gatctcatgc gagtcatcaa taggacaaaa     4740

aagttgtggt ttggggaggt ctgtttgtta cataaaaagg acctttcggt gtaagaaatt     4800

gccgttttta ccctgccctg gctggcatgt gagaagccat ggaaggttgt ggttgtaaat     4860

gagttgtcta aaggggtgca gaggcctgag gtttctaaaa gaaggtagat ttctacagag     4920

ctgagtgttg gttccttttt cttattggtt gaaaattacc tggtagtgat cagaaaactt     4980

agatgctatg taactaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aattcccgct     5040

catgagtttt gactattggt gagatgtttt ccgctacagt taacatgaca aatgtctcag     5100

tggcaaaaat cccctttttg taagccccca tagtctagag gcagttttct ttttaagaat     5160

catgccagag cctgagtcga gcagtatgct ttcttggttt ttgagagtaa ttgtgtaatt     5220

gtagagggag aaatccaatt ctaacctaag aactgggatt cttctgtcat cttgtaaacc     5280

gtatattgaa aaaaacagaa tgtcactaaa tgcatattaa gtcaagtatt ggaaagtata     5340

aaagaaaaat cattctgaca atttctaagc cagaagcaaa caagaattac tgaaatctac     5400

cccatgaata cttggaaggc agtaattgtg agtgacacct cagttcatca accccttaat     5460

aatatcagct taattttaat gacaactaaa tatgctgaag tgaggattta gtatttttta     5520

aaaaagcaaa acaaggttca gtagtcctca gcaattctcc aagtttctct ctttgcctaa     5580

aatggtcata gatcttgatt tctctgaatc gtgatgacca cacccagtca tcttcacagc     5640

ataattgcag gtggcagtaa agagagtgtg ctgggtaagg agcagttgct gggtcattcc     5700

ttgggccccg acctgcccgg ggagtagccc tgggggagag agggcagtgt tgcctatccc     5760

agaggtccca gcagtcacac tgctctgcag gccgggctct ctttatagcc agagaaatca     5820

ccttaatgca gtctctttag ttgtctgctg aagctgtagt tattatgggc cacttacatg     5880

aggctgagaa gtacgtgccg gagctcacac actgcctgtt gcggttctct taacatcagt     5940

tatcacagct gcctgtgggt cccgggtatt tccattcctg ccccttgttg gcccgaggaa     6000

ggatgtggaa agagcacctg gtgggatgaa ggtccaacag cctgtgcctc tccactgctg     6060

gccctggagc cggcagcagt gaggcattca ttgtctgtgt tgcggtgtat tcccagcttc     6120

agtgctcttt tcctttttgc ctgaaatgtt tatgcttctc tgcagccagt cctctaacaa     6180

atctcaagaa caaaggtaag acacttggtt tttgtttcca ggacccttca gaaggtgaca     6240

tcagatattc cctaaattca gacaatgagg gatacagagc gacttggcat gtattatttc     6300

tcccatgtaa ggacaaaggg acagattatt attgttattt ctgagacaga gtcttgctct     6360

gtagctcagg ctggagtgca gtggctcaat ctcagctcac cacaacctct gcctcctggc     6420

ttcaagcgat tcttctgcct cagcctcccc gaatagttgg gattacaggc acccaccacc     6480

acgcctggct aatttttgta tttttagtag agatggtttc accatgctgg ccaggctggt     6540

cttgaactcc tgacctcagg tgatcctccc gcctcagcct tccaaagtgc tgggattaca     6600

agcatgagcc accgcacccg gcctcacagt gacagattct gagaaacagc atgcaaaaca     6660

tttgaaccat tttctacatc tcccattgtt gcatagagag tgtgcaccgc tgctatcttg     6720

ccagatccac actggtcctc ccgaaagcca ggttcataca cagcaacttt ttaattattc     6780

taacagttac ccattaacag tcgactcctg tatttctgag agtcttgtac tcacctctga     6840

aatttaaaaa cgtataaaga gagcctgggt taatcagttc tgcagcccct acgtgacact     6900

gtgctagttc tccttcttct gtctcctcct taccctggcc ctgcacccct gtacttaaga     6960

gggagaggtg ggaggtgctg tctggtatca tttgctgcct cgccagtaga gggtgccgct     7020

gtgcagggta actgcccgcc tgctcccttc ctgacctccc ctgaccccga agatcactac     7080

ctctgtcatt caggcattgg ggtacatcct gataagtcgt gtcagaactg ccaatttcag     7140

gactgagatg tgtttttaaa aaacaaatcc ttataaactc cactttgtac tttagatttt     7200

aaaactgggg aaaaatgtga tattctttgg accacttttt taatttatat aagccttaat     7260

gaacagtgtc tatacatttg catacacaca cccccacccc agagtgttct cagtatgtca     7320

gagaaagtgc cacagcatta ggacgggagc ttggagaacg ttttctagaa aagggttagc     7380

ttcctgttgg catgaaattt tccaagcaaa cctcattaaa catctgttgt ttgttaaaga     7440

tgttccactg aaagcaacgc atgtttcaaa ggcacgtctt tccgttcgtt ggttttctgt     7500

gtgtaaggag tagcattgct gttggcgcct aacctcgcgt gcactgcatt ctcaaccccg     7560

taccagtgca tcatcagaag ccttcctcgt gaccataact ctgtgtctgc agatatgtgt     7620

tcccgtgtaa gccagttttc cccttttact cagactgatt tcacctagat tgtcacggtt     7680

tccttcatgt taactttgcg tgactttgtt cttcctttac tactctgtat gtaatatata     7740

tacatatata cgtacatatg ctgtccaaat atatttgtat atatttgtat agcattttta     7800

cacctttatt gagtaatctg gtttcgaaag gaggtgagag tttagtccct tctgcagttt     7860

tctccaagct gtgtcctgtg aatttcaacc cttggagcct aagaaaaccc taggaagatg     7920

atgttaattt gctgtcattt cctaattcag gatctatcat caaatgaaac atgaaaaaaa     7980

cagtgacttt taaggtgaaa agagtttcaa gcattccaaa taaattatca atgtttcata     8040

actttttatt ataaacccac ctcctaatag gaagccaagt actatttgat acagtggtaa     8100

aaaccaaact accttgaatt tttttaaggc aacttatgaa taatgctcat tttcacagtc     8160

agaatagctt taaaatatgg ttgaatttga tacacacagg aagttttctt gaagaacaat     8220

cctttcgctt ttcttttttc ttgagagatc taaagagaaa ctgtagattg ttttcctgac     8280

agcaaaagac taatgtgaca aaatgaagtc attgtaaaga agcgatgcaa cttgtcaaat     8340

atttaataaa gaattatgga agctggaaca ttttctac                             8378


<210>  1372
<211>  2682
<212>  DNA
<213>  homo sapiens

<400>  1372
ccccacccgc ttccggccgc ggctcggttc tcccgcctcc gcctccgccg cggctcgtgg       60

ttgtcccgcc atggcactgt cgcgggggct gccccgggag ctggctgagg cggtggccgg      120

gggccgggtg ctggtggtgg gggcgggcgg catcggctgc gagctcctca agaatctcgt      180

gctcaccggt ttctcccaca tcgacctgat tgatctggat actattgatg taagcaacct      240

caacagacag tttttgtttc aaaagaaaca tgttggaaga tcaaaggcac aggttgccaa      300

ggaaagtgta ctgcagtttt acccgaaagc taatatcgtt gcctaccatg acagcatcat      360

gaaccctgac tataatgtgg aatttttccg acagtttata ctggttatga atgctttaga      420

taacagagct gcccgaaacc atgttaatag aatgtgcctg gcagctgatg ttcctcttat      480

tgaaagtgga acagctgggt atcttggaca agtaactact atcaaaaagg gtgtgaccga      540

gtgttatgag tgtcatccta agccgaccca gagaaccttt cctggctgta caattcgtaa      600

cacaccttca gaacctatac attgcatcgt ttgggcaaag tacttgttca accagttgtt      660

tggggaagaa gatgctgatc aagaagtatc tcctgacaga gctgaccctg aagctgcctg      720

ggaaccaacg gaagccgaag ccagagctag agcatctaat gaagatggtg acattaaacg      780

tatttctact aaggaatggg ctaaatcaac tggatatgat ccagttaaac tttttaccaa      840

gctttttaaa gatgacatca ggtatctgtt gacaatggac aaactatggc ggaaaaggaa      900

acctccagtt ccgttggact gggctgaagt acaaagtcaa ggagaagaaa cgaatgcatc      960

agatcaacag aatgaacccc agttaggcct gaaagaccag caggttctag atgtaaagag     1020

ctatgcacgt cttttttcaa agagcatcga gactttgaga gttcatttag cagaaaaggg     1080

ggatggagct gagctcatat gggataagga tgacccatct gcaatggatt ttgtcacctc     1140

tgctgcaaac ctcaggatgc atattttcag tatgaatatg aagagtagat ttgatatcaa     1200

atcaatggca gggaacatta ttcctgctat tgctactact aatgcagtaa ttgctgggtt     1260

gatagtattg gaaggattga agattttatc aggaaaaata gaccagtgca gaacaatttt     1320

tttgaataaa caaccaaacc caagaaagaa gcttcttgtg ccttgtgcac tggatcctcc     1380

caaccccaat tgttatgtat gtgccagcaa gccagaggtg actgtgcggc tgaatgtcca     1440

taaagtgact gttctcacct tacaagacaa gatagtgaaa gaaaaatttg ctatggtagc     1500

accagatgtc caaattgaag atgggaaagg aacaatccta atatcttccg aagagggaga     1560

gacggaagct aataatcaca agaagttgtc agaatttgga attagaaatg gcagccggct     1620

tcaagcagat gacttcctcc aggactatac tttattgatc aacatccttc atagtgaaga     1680

cctaggaaag gacgttgaat ttgaagttgt tggtgatgcc ccggaaaaag tggggcccaa     1740

acaagctgaa gatgctgcca aaagcataac caatggcagt gatgatggag ctcagccctc     1800

cacctccaca gctcaagagc aagatgacgt tctcatagtt gattcagatg aagaagattc     1860

ttcaaataat gccgacgtca gtgaagaaga gagaagccgc aagaggaaat tagatgagaa     1920

agagaatctc agtgcaaaga ggtcacgtat agaacagaag gaagagcttg atgatgtcat     1980

agcattagat tgaacagaaa tgcctctaaa cagaaccctc ttactattta gtttatctgg     2040

gcagaaccag attgttatgt cctttgttcc aaagggaaaa aattgacagc agtgacttga     2100

aaatgattct gctccctttg aaagcattca ttttgctaga actgttagac acattgcagt     2160

atgctgtatt gaaagtagga atatagtttt aaaaaccctt tgaacaaagt gtgtgcataa     2220

ccagtcatga gataaaacaa cacaatgcat gttgcctttt taatgtaaat acccgtaggt     2280

atcattaata gtttcaaaat attgtggttt agtaaagttg atacctggtt ataaatatta     2340

tgcctttatt tttggctaga agaagaatta tttttagcct agatctaacc attttcatac     2400

tcttaactga ttgaaacaga ttcaaagaag tatcgagtgc tatgcattga aacttgtttt     2460

taaatgttag atggcactat gtatattaat gtaaaacaat gttaatttac tcaagttttc     2520

agtttgtacc gcctggtatg tctgtgtaag aagccaattt ttgtgtattg ttacagtttc     2580

aggttattta tattcgatgt tttgtaaaac tcaaataacg actatactta tggaccaaat     2640

aaatggcatc tgcattcttg ttacaaaaaa aaaaaaaaaa aa                        2682


<210>  1373
<211>  3968
<212>  DNA
<213>  homo sapiens

<400>  1373
gtcgcgggca gctggcgccg cgcggtcctg ctctgccggt cgcacggacg caccggcggg       60

ccgccggccg gagggacggg gcgggagctg ggcccgcgga cagcgagccg gagcgggagc      120

cgcgcgtagc gagccgggct ccggcgctcg ccagtctccc gagcggcgcc cgcctcccgc      180

cggtgcccgc gccgggccgt ggggggcagc atgcccgcgc gcgctgcctg aggacgccgc      240

ggcccccgcc cccgccatgg gcgcccctgc ctgcgccctc gcgctctgcg tggccgtggc      300

catcgtggcc ggcgcctcct cggagtcctt ggggacggag cagcgcgtcg tggggcgagc      360

ggcagaagtc ccgggcccag agcccggcca gcaggagcag ttggtcttcg gcagcgggga      420

tgctgtggag ctgagctgtc ccccgcccgg gggtggtccc atggggccca ctgtctgggt      480

caaggatggc acagggctgg tgccctcgga gcgtgtcctg gtggggcccc agcggctgca      540

ggtgctgaat gcctcccacg aggactccgg ggcctacagc tgccggcagc ggctcacgca      600

gcgcgtactg tgccacttca gtgtgcgggt gacagacgct ccatcctcgg gagatgacga      660

agacggggag gacgaggctg aggacacagg tgtggacaca ggggcccctt actggacacg      720

gcccgagcgg atggacaaga agctgctggc cgtgccggcc gccaacaccg tccgcttccg      780

ctgcccagcc gctggcaacc ccactccctc catctcctgg ctgaagaacg gcagggagtt      840

ccgcggcgag caccgcattg gaggcatcaa gctgcggcat cagcagtgga gcctggtcat      900

ggaaagcgtg gtgccctcgg accgcggcaa ctacacctgc gtcgtggaga acaagtttgg      960

cagcatccgg cagacgtaca cgctggacgt gctggagcgc tccccgcacc ggcccatcct     1020

gcaggcgggg ctgccggcca accagacggc ggtgctgggc agcgacgtgg agttccactg     1080

caaggtgtac agtgacgcac agccccacat ccagtggctc aagcacgtgg aggtgaatgg     1140

cagcaaggtg ggcccggacg gcacacccta cgttaccgtg ctcaaggtgt ccctggagtc     1200

caacgcgtcc atgagctcca acacaccact ggtgcgcatc gcaaggctgt cctcagggga     1260

gggccccacg ctggccaatg tctccgagct cgagctgcct gccgacccca aatgggagct     1320

gtctcgggcc cggctgaccc tgggcaagcc ccttggggag ggctgcttcg gccaggtggt     1380

catggcggag gccatcggca ttgacaagga ccgggccgcc aagcctgtca ccgtagccgt     1440

gaagatgctg aaagacgatg ccactgacaa ggacctgtcg gacctggtgt ctgagatgga     1500

gatgatgaag atgatcggga aacacaaaaa catcatcaac ctgctgggcg cctgcacgca     1560

gggcgggccc ctgtacgtgc tggtggagta cgcggccaag ggtaacctgc gggagtttct     1620

gcgggcgcgg cggcccccgg gcctggacta ctccttcgac acctgcaagc cgcccgagga     1680

gcagctcacc ttcaaggacc tggtgtcctg tgcctaccag gtggcccggg gcatggagta     1740

cttggcctcc cagaagtgca tccacaggga cctggctgcc cgcaatgtgc tggtgaccga     1800

ggacaacgtg atgaagatcg cagacttcgg gctggcccgg gacgtgcaca acctcgacta     1860

ctacaagaag acaaccaacg gccggctgcc cgtgaagtgg atggcgcctg aggccttgtt     1920

tgaccgagtc tacactcacc agagtgacgt ctggtccttt ggggtcctgc tctgggagat     1980

cttcacgctg gggggctccc cgtaccccgg catccctgtg gaggagctct tcaagctgct     2040

gaaggagggc caccgcatgg acaagcccgc caactgcaca cacgacctgt acatgatcat     2100

gcgggagtgc tggcatgccg cgccctccca gaggcccacc ttcaagcagc tggtggagga     2160

cctggaccgt gtccttaccg tgacgtccac cgacgagtac ctggacctgt cggcgccttt     2220

cgagcagtac tccccgggtg gccaggacac ccccagctcc agctcctcag gggacgactc     2280

cgtgtttgcc cacgacctgc tgcccccggc cccacccagc agtgggggct cgcggacgtg     2340

aagggccact ggtccccaac aatgtgaggg gtccctagca gcccaccctg ctgctggtgc     2400

acagccactc cccggcatga gactcagtgc agatggagag acagctacac agagctttgg     2460

tctgtgtgtg tgtgtgtgcg tgtgtgtgtg tgtgtgtgca catccgcgtg tgcctgtgtg     2520

cgtgcgcatc ttgcctccag gtgcagaggt accctgggtg tccccgctgc tgtgcaacgg     2580

tctcctgact ggtgctgcag caccgagggg cctttgttct ggggggaccc agtgcagaat     2640

gtaagtgggc ccacccggtg ggacccccgt ggggcaggga gctgggcccg acatggctcc     2700

ggcctctgcc tttgcaccac gggacatcac agggtgggcc tcggcccctc ccacacccaa     2760

agctgagcct gcagggaagc cccacatgtc cagcaccttg tgcctggggt gttagtggca     2820

ccgcctcccc acctccaggc tttcccactt cccaccctgc ccctcagaga ctgaaattac     2880

gggtacctga agatgggagc ctttaccttt tatgcaaaag gtttattccg gaaactagtg     2940

tacatttcta taaatagatg ctgtgtatat ggtatatata catatatata tataacatat     3000

atggaagagg aaaaggctgg tacaacggag gcctgcgacc ctgggggcac aggaggcagg     3060

catggccctg ggcggggcgt gggggggcgt ggagggaggc cccagggggt ctcacccatg     3120

caagcagagg accagggcct tttctggcac cgcagttttg ttttaaaact ggacctgtat     3180

atttgtaaag ctatttatgg gcccctggca ctcttgttcc cacaccccaa cacttccagc     3240

atttagctgg ccacatggcg gagagtttta atttttaact tattgacaac cgagaaggtt     3300

tatcccgccg atagagggac ggccaagaat gtacgtccag cctgccccgg agctggagga     3360

tcccctccaa gcctaaaagg ttgttaatag ttggaggtga ttccagtgaa gatattttat     3420

ttcctttgtc ctttttcagg agaattagat ttctatagga tttttcttta ggagatttat     3480

tttttggact tcaaagcaag ctggtatttt catacaaatt cttctaattg ctgtgtgtcc     3540

caggcaggga gacggtttcc agggaggggc cggccctgtg tgcaggttcc gatgttatta     3600

gatgttacaa gtttatatat atctatatat ataatttatt gagtttttac aagatgtatt     3660

tgttgtagac ttaacacttc ttacgcaatg cttctagagt tttatagcct ggactgctac     3720

ctttcaaagc ttggagggaa gccgtgaatt cagttggttc gttctgtact gttactgggc     3780

cctgagtctg ggcagctgtc ccttgcttgc ctgcagggcc atggctcagg gtggtctctt     3840

cttggggccc agtgcatggt ggccagaggt gtcacccaaa ccggcaggtg cgattttgtt     3900

aacccagcga cgaactttcc gaaaaataaa gacacctggt tgctaacctg gaaaaaaaaa     3960

aaaaaaaa                                                              3968


<210>  1374
<211>  5157
<212>  DNA
<213>  homo sapiens

<400>  1374
tgcagcccgg cgcgcctgag cctgcgagtc cgcgagccag cgagctgcgg ctgcggcctc       60

ccctgcgcgc agctacccgg gcgtcccggc ccgcggcccc gctaaccccg gggcccgcgc      120

ccccgcggca gggatgcatc atggccacgc tggcttgccg ggtgcagttc ttggacgaca      180

cggacccttt caacagcacc aacttccccg agcccagccg gccgccgctg ttcacgttcc      240

gcgaggacct cgcgctcggc acccagctgg cgggggtcca taggctgctg caggcgccgc      300

acaagctgga tgactgtact ctgcagctct ctcacaatgg cgcctacctg gatttggagg      360

ccaccctggc agagcagcgg gatgagttgg aaggcttcca ggatgacgcc gggcggggca      420

agaagcacag catcatccta aggacgcagc tgtctgtgag ggtccatgcc tgcatcgaaa      480

aactatacaa ctccagcgga cgagatttga gaagggccct cttctccctg aagcagatat      540

ttcaggatga caaggatttg gtgcatgaat ttgtagtggc tgaaggtctg acatgtttga      600

tcaaggtggg agctgaggct gatcagaact atcagaacta catcttaagg gctttgggcc      660

agattatgtt gtatgtggat ggaatgaatg gagtaataaa ccgcaatgaa accattcagt      720

ggctgtacac tctcattggg tcaaagttcc gcctggtggt gaagacagcc ctgaagctgc      780

tgctcgtctt tgtagagtac tcggagtcca acgcacctct cctaattcag gctgtcactg      840

ctgttgacac gaaaagaggg gtcaaacctt ggtcaaatat catggaaatc ctggaggaaa      900

aagatggagt tgatacggag ctactggttt atgcaatgac tttggtgaac aagacgttat      960

caggactacc agaccaagac accttctacg acgtcgtgga ctgcctggag gagctgggca     1020

ttgctgctgt gtcccagagg cacttgaaca agaaagggac tgacctggac ttagtggagc     1080

aactcaacat ttatgaggtg gcgctcaggc acgaggatgg cgatgagacc acggagccac     1140

cccccagtgg gtgccgggac cggaggaggg ccagcgtgtg ttccagtggc ggaggcgagc     1200

accggggcct ggaccgcaga aggagccgca ggcactcggt gcagagcatc aagagcaccc     1260

tgtcggcccc caccagtccc tgctcccagt cagctcccag cttcaagccc aaccaagtgc     1320

gagatctgcg tgaaaaatac agcaattttg gcaataactc ttatcactcc tcaagaccct     1380

catctggatc cagtgtgccc accaccccca catcatccgt ctcaccccca caggaggcca     1440

ggttggaaag gtcatcaccg agtggtcttc tcacatcatc cttcaggcag caccaagagt     1500

cactggcagc agagagagag aggcggcggc aggagagaga agaaaggttg cagagaatag     1560

agcgggaaga aagaaacaaa ttcagccgag attatttaga caaaagagag gagcaaaggc     1620

aagcaagaga agaaagatac aaatacttgg aacagttggc agctgaggag cacgagaagg     1680

agctgagaag ccggagtgtg agccggggca gagccgacct ctccttggac ctgacctcgc     1740

cagcagcccc agcctgcctg gctcctctga gccatagccc ctcatcttca gactctcaag     1800

aggctctcac ggtgtctgcc tcctccccag gaacccctca ccatccccaa gcaagtgccg     1860

gggatcctga acccgaatca gaggcagaac cggaagcaga ggcaggggcg gggcaggttg     1920

ctgatgaagc tggccaggac atagcctctg cccacgaggg tgcagagact gaagtggagc     1980

aggcactaga gcaagagccg gaagaaagag cctccctcag tgaaaaagag aggcagaacg     2040

agggggtgaa cgagagggac aactgctctg cctccagcgt ctcgtcctcc agcagcacgt     2100

tggagaggga ggagaaggag gacaagctct ccagggacag gacaactggt ttgtggcccg     2160

caggtgtcca ggatgcaggt gtaaatggac agtgtggcga catcctcacc aacaaacggt     2220

tcatgcttga catgctgtat gcccataaca ggaagtctcc ggatgatgag gagaaggggg     2280

atggggaggc tgggaggacc cagcaggagg cagaggcggt agccagcctt gctaccagga     2340

tatccaccct gcaggccaac tctcagaccc aggatgagag tgtcaggagg gtggatgtcg     2400

gctgtttgga caatcggggc agtgtgaaag catttgctga gaaattcaac agtggggacc     2460

tggggagagg ttccatctcc cctgatgctg agcccaatga caaggtccca gaaacagcgc     2520

cggtgcagcc gaagacagag tctgattaca tctgggacca gctcatggcc aatccaagag     2580

agctcagaat ccaagacatg gatttcactg acctggggga ggaggatgac attgatgtcc     2640

tagatgtgga cctgggtcac agggaggccc ctgggccacc tcccccaccc ccacccacct     2700

ttctgggttt gccgccccca ccccctccgc ccctgttgga cagcattcct ccccctcctg     2760

tccctggtaa tttattggtt cctcctcctc cagtgttcaa cgctcctcag ggcttagggt     2820

ggtcccaggt acccaggggt cagcccacat tcactaagaa aaagaagacc atccgtttgt     2880

tctggaatga agttcggcct tttgactggc catgtaaaaa caaccgacgc tgcagagaat     2940

tcctgtggtc aaaactggaa cccattaagg tggacacttc cagactggag cacctgtttg     3000

agtctaaatc caaggaactg tctgtctcaa agaaaactgc tgcagatgga aaaaggcaag     3060

agatcattgt tctggattcc aagaggagta acgccatcaa tattggtctg acggtgctgc     3120

cccctccaag gacgattaag atcgccattt tgaattttga tgagtatgcc ttaaacaaag     3180

aaggaatcga gaaaattcta acgatgattc ccaccgatga ggagaagcag aaaatccagg     3240

aagctcagct ggccaaccct gaaatccccc tgggcagtgc agagcagttc ctcctcaccc     3300

tgtcctccat cagcgagctc tctgcacgac ttcacctctg ggcattcaaa atggattatg     3360

aaactacaga aaaggaagta gcagaaccac tcctggacct gaaggaagga atagaccagt     3420

tggagaacaa taaaaccttg ggctttatcc tgtctactct cttagccatt gggaactttc     3480

taaatggaac taatgccaaa gcgtttgagt taagctacct cgagaaggtt ccagaagtca     3540

aagacacagt gcacaagcag tcgcttctcc accatgtgtg caccatggtg gtagaaaact     3600

tcccagacag ctccgatctg tactcggaga tcggggccat caccaggtca gccaaggttg     3660

actttgatca acttcaggat aatttatgtc agatggagag aagatgcaaa gcttcatggg     3720

atcacctcaa ggcaattgca aaacatgaaa tgaaaccagt tttaaaacaa cggatgtcag     3780

agttcctgaa agactgtgca gagcgaatta taattttaaa gattgtccat agaaggataa     3840

tcaacagatt ccactccttt ttactcttta tgggccatcc accttatgca attcgggaag     3900

tgaacataaa caaattctgc aggattatta gtgaatttgc actagagtat cgcacaacca     3960

gggaaagggt tttgcagcag aaacagaaac gggccaacca cagagagaga aataagacca     4020

gagggaagat gatcaccgat tctggcaagt tctccggcag ttctccggcg cccccaagcc     4080

agccgcaggg tctgagctat gcggaggacg cggctgagca cgagaacatg aaggctgtgc     4140

tgaaaacctc gtccccctcc gtggaggacg ccacccccgc gctgggcgtc cgcacacgca     4200

gccgagcaag ccgaggatcc actagttcct ggactatggg aactgatgac tcgcccaatg     4260

tcacagatga tgcagctgat gagatcatgg accgcatcgt caagtcagcc acccaagtgc     4320

ccagtcagcg agtggtgccg agggagagga aacgatcccg ggccaaccgg aaatctttgc     4380

gaagaaccct gaagagcggc ctgaccccag aagaagccag agccctgggc ttggttggca     4440

cctcggagtt gcagctgtga cactcatagg ttactcccag gagtgtgctg agcagaaggc     4500

aagctcttgc tggatgaaac ccctccaggt ggggttgggg agacttgata ttcacatcca     4560

acagtttgaa aagggagagc tcaattccca gcgtcacccc atggcttgtg ttgcctgcta     4620

cgcattgact tggatctcca ggagtcccct gcacatacct tctccatcgt gtcagctgtg     4680

tttctcttga ttccgtgaca cccggtttat tagttcaaaa gtgtgacacc ttttctgggc     4740

aaggaacagc ccctttaagg agcaaatcac ttctgtcaca gttattatgg taatatgagg     4800

caatctgatt agcttcacag actgagtctc cacaacacca aaatatccag atgtaaaccc     4860

caaacttgta cacaaaagaa agcacagatt gtttacctgt tgtggatttt agatgtaaca     4920

aatgtttata caaatacata catgtacacc atgtttcaaa tactaaataa atagagttta     4980

atgccataat gagaaacttt tattcttctg ggaacaggac cttaaacagt tccacaggct     5040

cgcctcttca gaatggcaaa actcttctca gtgtcctcag aagcaccctc gcttggaacg     5100

gccttcagat cctttgggct gtattttgtt aatagagtga gtaacatcaa aaaaaaa        5157


<210>  1375
<211>  5157
<212>  DNA
<213>  homo sapiens

<400>  1375
tgcagcccgg cgcgcctgag cctgcgagtc cgcgagccag cgagctgcgg ctgcggcctc       60

ccctgcgcgc agctacccgg gcgtcccggc ccgcggcccc gctaaccccg gggcccgcgc      120

ccccgcggca gggatgcatc atggccacgc tggcttgccg ggtgcagttc ttggacgaca      180

cggacccttt caacagcacc aacttccccg agcccagccg gccgccgctg ttcacgttcc      240

gcgaggacct cgcgctcggc acccagctgg cgggggtcca taggctgctg caggcgccgc      300

acaagctgga tgactgtact ctgcagctct ctcacaatgg cgcctacctg gatttggagg      360

ccaccctggc agagcagcgg gatgagttgg aaggcttcca ggatgacgcc gggcggggca      420

agaagcacag catcatccta aggacgcagc tgtctgtgag ggtccatgcc tgcatcgaaa      480

aactatacaa ctccagcgga cgagatttga gaagggccct cttctccctg aagcagatat      540

ttcaggatga caaggatttg gtgcatgaat ttgtagtggc tgaaggtctg acatgtttga      600

tcaaggtggg agctgaggct gatcagaact atcagaacta catcttaagg gctttgggcc      660

agattatgtt gtatgtggat ggaatgaatg gagtaataaa ccgcaatgaa accattcagt      720

ggctgtacac tctcattggg tcaaagttcc gcctggtggt gaagacagcc ctgaagctgc      780

tgctcgtctt tgtagagtac tcggagtcca acgcacctct cctaattcag gctgtcactg      840

ctgttgacac gaaaagaggg gtcaaacctt ggtcaaatat catggaaatc ctggaggaaa      900

aagatggagt tgatacggag ctactggttt atgcaatgac tttggtgaac aagacgttat      960

caggactacc agaccaagac accttctacg acgtcgtgga ctgcctggag gagctgggca     1020

ttgctgctgt gtcccagagg cacttgaaca agaaagggac tgacctggac ttagtggagc     1080

aactcaacat ttatgaggtg gcgctcaggc acgaggatgg cgatgagacc acggagccac     1140

cccccagtgg gtgccgggac cggaggaggg ccagcgtgtg ttccagtggc ggaggcgagc     1200

accggggcct ggaccgcaga aggagccgca ggcactcggt gcagagcatc aagagcaccc     1260

tgtcggcccc caccagtccc tgctcccagt cagctcccag cttcaagccc aaccaagtgc     1320

gagatctgcg tgaaaaatac agcaattttg gcaataactc ttatcactcc tcaagaccct     1380

catctggatc cagtgtgccc accaccccca catcatccgt ctcaccccca caggaggcca     1440

ggttggaaag gtcatcaccg agtggtcttc tcacatcatc cttcaggcag caccaagagt     1500

cactggcagc agagagagag aggcggcggc aggagagaga agaaaggttg cagagaatag     1560

agcgggaaga aagaaacaaa ttcagccgag attatttaga caaaagagag gagcaaaggc     1620

aagcaagaga agaaagatac aaatacttgg aacagttggc agctgaggag cacgagaagg     1680

agctgagaag ccggagtgtg agccggggca gagccgacct ctccttggac ctgacctcgc     1740

cagcagcccc agcctgcctg gctcctctga gccatagccc ctcatcttca gactctcaag     1800

aggctctcac ggtgtctgcc tcctccccag gaacccctca ccatccccaa gcaagtgccg     1860

gggatcctga acccgaatca gaggcagaac cggaagcaga ggcaggggcg gggcaggttg     1920

ctgatgaagc tggccaggac atagcctctg cccacgaggg tgcagagact gaagtggagc     1980

aggcactaga gcaagagccg gaagaaagag cctccctcag tgaaaaagag aggcagaacg     2040

agggggtgaa cgagagggac aactgctctg cctccagcgt ctcgtcctcc agcagcacgt     2100

tggagaggga ggagaaggag gacaagctct ccagggacag gacaactggt ttgtggcccg     2160

caggtgtcca ggatgcaggt gtaaatggac agtgtggcga catcctcacc aacaaacggt     2220

tcatgcttga catgctgtat gcccataaca ggaagtctcc ggatgatgag gagaaggggg     2280

atggggaggc tgggaggacc cagcaggagg cagaggcggt agccagcctt gctaccagga     2340

tatccaccct gcaggccaac tctcagaccc aggatgagag tgtcaggagg gtggatgtcg     2400

gctgtttgga caatcggggc agtgtgaaag catttgctga gaaattcaac agtggggacc     2460

tggggagagg ttccatctcc cctgatgctg agcccaatga caaggtccca gaaacagcgc     2520

cggtgcagcc gaagacagag tctgattaca tctgggacca gctcatggcc aatccaagag     2580

agctcagaat ccaagacatg gatttcactg acctggggga ggaggatgac attgatgtcc     2640

tagatgtgga cctgggtcac agggaggccc ctgggccacc tcccccaccc ccacccacct     2700

ttctgggttt gccgccccca ccccctccgc ccctgttgga cagcattcct ccccctcctg     2760

tccctggtaa tttattggtt cctcctcctc cagtgttcaa cgctcctcag ggcttagggt     2820

ggtcccaggt acccaggggt cagcccacat tcactaagaa aaagaagacc atccgtttgt     2880

tctggaatga agttcggcct tttgactggc catgtaaaaa caaccgacgc tgcagagaat     2940

tcctgtggtc aaaactggaa cccattaagg tggacacttc cagactggag cacctgtttg     3000

agtctaaatc caaggaactg tctgtctcaa agaaaactgc tgcagatgga aaaaggcaag     3060

agatcattgt tctggattcc aagaggagta acgccatcaa tattggtctg acggtgctgc     3120

cccctccaag gacgattaag atcgccattt tgaattttga tgagtatgcc ttaaacaaag     3180

aaggaatcga gaaaattcta acgatgattc ccaccgatga ggagaagcag aaaatccagg     3240

aagctcagct ggccaaccct gaaatccccc tgggcagtgc agagcagttc ctcctcaccc     3300

tgtcctccat cagcgagctc tctgcacgac ttcacctctg ggcattcaaa atggattatg     3360

aaactacaga aaaggaagta gcagaaccac tcctggacct gaaggaagga atagaccagt     3420

tggagaacaa taaaaccttg ggctttatcc tgtctactct cttagccatt gggaactttc     3480

taaatggaac taatgccaaa gcgtttgagt taagctacct cgagaaggtt ccagaagtca     3540

aagacacagt gcacaagcag tcgcttctcc accatgtgtg caccatggtg gtagaaaact     3600

tcccagacag ctccgatctg tactcggaga tcggggccat caccaggtca gccaaggttg     3660

actttgatca acttcaggat aatttatgtc agatggagag aagatgcaaa gcttcatggg     3720

atcacctcaa ggcaattgca aaacatgaaa tgaaaccagt tttaaaacaa cggatgtcag     3780

agttcctgaa agactgtgca gagcgaatta taattttaaa gattgtccat agaaggataa     3840

tcaacagatt ccactccttt ttactcttta tgggccatcc accttatgca attcgggaag     3900

tgaacataaa caaattctgc aggattatta gtgaatttgc actagagtat cgcacaacca     3960

gggaaagggt tttgcagcag aaacagaaac gggccaacca cagagagaga aataagacca     4020

gagggaagat gatcaccgat tctggcaagt tctccggcag ttctccggcg cccccaagcc     4080

agccgcaggg tctgagctat gcggaggacg cggctgagca cgagaacatg aaggctgtgc     4140

tgaaaacctc gtccccctcc gtggaggacg ccacccccgc gctgggcgtc cgcacacgca     4200

gccgagcaag ccgaggatcc actagttcct ggactatggg aactgatgac tcgcccaatg     4260

tcacagatga tgcagctgat gagatcatgg accgcatcgt caagtcagcc acccaagtgc     4320

ccagtcagcg agtggtgccg agggagagga aacgatcccg ggccaaccgg aaatctttgc     4380

gaagaaccct gaagagcggc ctgaccccag aagaagccag agccctgggc ttggttggca     4440

cctcggagtt gcagctgtga cactcatagg ttactcccag gagtgtgctg agcagaaggc     4500

aagctcttgc tggatgaaac ccctccaggt ggggttgggg agacttgata ttcacatcca     4560

acagtttgaa aagggagagc tcaattccca gcgtcacccc atggcttgtg ttgcctgcta     4620

cgcattgact tggatctcca ggagtcccct gcacatacct tctccatcgt gtcagctgtg     4680

tttctcttga ttccgtgaca cccggtttat tagttcaaaa gtgtgacacc ttttctgggc     4740

aaggaacagc ccctttaagg agcaaatcac ttctgtcaca gttattatgg taatatgagg     4800

caatctgatt agcttcacag actgagtctc cacaacacca aaatatccag atgtaaaccc     4860

caaacttgta cacaaaagaa agcacagatt gtttacctgt tgtggatttt agatgtaaca     4920

aatgtttata caaatacata catgtacacc atgtttcaaa tactaaataa atagagttta     4980

atgccataat gagaaacttt tattcttctg ggaacaggac cttaaacagt tccacaggct     5040

cgcctcttca gaatggcaaa actcttctca gtgtcctcag aagcaccctc gcttggaacg     5100

gccttcagat cctttgggct gtattttgtt aatagagtga gtaacatcaa aaaaaaa        5157


<210>  1376
<211>  4711
<212>  DNA
<213>  homo sapiens

<400>  1376
agtgagctat ggggacacta ctgcactgta gcctgggcaa cagagcaaga ccttgtctca       60

aaaatgtata tatattttgg gctttttttc ctaaaacggg aactacaaca gcatatttgc      120

gagctgatga gagtgaccca gcagagaggg aaatggatca gctctgttga agatgcactg      180

gacaccagaa cacgcccagc ccctcaacca gtggccagag cagcacctgg acgtctcctc      240

caccaccccg tcgccggccc acaagttgga gttgccccct gggggtcgcc aacgctgcca      300

ctacgcttgg gcacacgacg acatctcagc cctcactgcc tccaacctcc taaagcgcta      360

tgcagagaag tactctgggg tcttggattc tccctacgag cgtccggccc tgggcgggta      420

cagcgacgcc tccttcctca acggcgccaa aggggatccc gagccctggc cagggccgga      480

gccaccctac cccttggcct cactccacga aggcctccca ggaaccaaat cgggcggtgg      540

cggcggttcc ggggccctgg ggggctcccc agttttagcc gggaacctcc ctgaacccct      600

ctacgccggc aatgcgtgcg ggggcccatc ggcggcgccc gagtacgcgg ccggctacgg      660

cggggggtac ctggcgccgg gttactgcgc gcagacgggc gccgcgctgc ccccgccgcc      720

cccggccgcg ctcctgcagc ccccaccgcc tccggggtac gggccctcag cgccgctgta      780

caactatccc gcagggggct acgcagcgca gcccggctat ggcgcgctcc cgccgccccc      840

aggcccaccc ccggccccct acctgacccc gggcctgccc gcgcccacgc ccctgcccgc      900

gccggcaccg cccaccgcct atggcttccc cacggccgcg ccgggtgccg aatccgggct      960

gtcgctgaag cgcaaggccg ccgacgaggg gcccgagggc cgctaccgca agtacgcgta     1020

cgagcccgcc aaggcccccg tggctgacgg agcctcctac cccgccgcgg acaacggcga     1080

atgtcggggc aacgggttcc gggccaagcc gccaggagcc gcggaggagg cgtcgggcaa     1140

gtacggtggc ggcgtccccc tcaaggtcct gggctccccc gtctacggcc cgcaactgga     1200

gccctttgaa aagttcccgg agcgggcccc ggctcctcgt ggggggttcg ccgtgccgtc     1260

gggggagact cccaaaggcg tggaccctgg ggccctggag ctggtgacga gcaagatggt     1320

ggactgcggg cccccggtgc agtgggcgga tgtggcgggc cagggcgcgc tcaaggcggc     1380

gctggaggag gagctggtgt ggcccctgct caggccgccc gcctacccgg gcagcctgcg     1440

cccgccgcgg accgtcctgc tctttgggcc gcggggcgcg ggcaaagcgc tgctgggccg     1500

ctgcctcgcc acgcagctgg gcgccacgct gttgcgcctg cgcggcgcga ccctggctgc     1560

gcccggcgcc gccgagggcg cgcgcctcct ccaggccgcc ttcgcggccg cgcgctgccg     1620

cccaccctcc gtactcctca tcagcgagct agaggcgctg ctccccgccc gggacgacgg     1680

cgcggcggca gggggcgcgc tgcaggtgcc gctcctggcc tgcctggacg ggggctgcgg     1740

cgcgggggct gacggcgtgc tggttgtggg caccacctcg cggcccgcgg ctctggacga     1800

ggcgacccgc cggcgcttct ctctccgctt ctacgtggcg ctgcccgaca gcccggcccg     1860

cgggcagatc ctgcagcggg cgctggccca gcagggctgc gcgctcagtg agcgggaact     1920

ggcggcgctg gtgcagggca cgcagggctt ctctgggggc gagctggggc agctgtgcca     1980

gcaggcggcg gccggggcgg gcctcccggg gctgcagcgc cccctctcct acaaggacct     2040

ggaggcggcg ctggccaagg tgggccctag ggcctctgcc aaggaactgg actcgttcgt     2100

ggagtgggac aaaatgtacg gctccggaca ctgacggcgc gcgggggagg ccgcgggagc     2160

cgcagtccct ccgtccccgc cgcctccgcg tgggagggat gtcactgact aaacccggct     2220

ggcaggggct ggagtggtga atgtgggatc ggggacagga ggggtctgcc ggtggatatt     2280

ttttttttcg tgggaaggaa aatgcttctg ccaggcagat gccatatgcg ccgtgtactc     2340

aggtttttcc tatttattgt ggactggaag ctcgccatct ccgcccggca gaccgggcag     2400

atccggcatg ggctggcacc cggggcctta agaactcctg ctctcttgcc acaacgcttt     2460

tgtctcctcg ctatctgaat ggcaccctcc ttctccctca ctctctccat cccattctct     2520

gcattctctt ggttttctct cccttttgct ttgtcgctga cacccctgcc caccccatgc     2580

tggccctgtt tctctcctgc ccctccctcc ccagctctcc atccctcacc ctctgtgctt     2640

ctgtctccat ccctggctct ccagcgtccc tggccttttg gtccctgagc tttaatgcct     2700

ttccctgcct tctgttctta tttggactgc agtggccctt tgcaggagct ctggaggccc     2760

aggggctgag gaggagggtt acccctctac ccatctgaaa cctagggtct agggggatca     2820

aggaaaaaaa gtccccaaag aaggggaatt ttttgtttgt ttttgagggg agatcccaga     2880

aatgtagctt gtttcatatt ttagtcttct tatttttgta aaatgtgtag aatttgctgt     2940

ttttcttttt cttttgacaa ctcaggaaga aactgacctc agaaagaatg ttagactttg     3000

gctgctctcc tgtgtgcccc tcacacctgc cccctccccc ccactccatc caggggacca     3060

aattctccca gacactcaaa aaatgagact tacggggaag gggagaggaa gacccagagg     3120

cctcagtgaa accccagcta ttcctggtca gaagcagaat gtattcctaa gggcttcctc     3180

cccagggccg aggcctaggc atgaatgtgg ggagtgggct gtggggtttg agagaaggga     3240

ggccttattc ctctcctgct gctccccacc ccctgcccca cccaacccct ccgctgagtg     3300

ttttctgtga agggctatcc agagttagga tgcccttgcc caattccttc ctgagaccca     3360

gaaggtaggg tgggagggcc caaatgggaa ggtgacctaa gcagaaagtc tccagaaagg     3420

tcatgtcccc tggccctgcc ttggcagagg tccccagtga cttatgctag gaggattcca     3480

tctgggtaga cagtctggcc acaaaatcag ctactggacc tcagccatct ctgctggagg     3540

ctctgaggag gagtgagcat ccctcacttg tgggggctct gtgaggaaat gtgccttccc     3600

cattcccccg gagtcctagg tctggagctc cagggctggg agagggtgag ggagatgggc     3660

aggggtgttt tctctgacct tgggggctta gtctcagtcc tgcctgaact ttccactagg     3720

cttggaaccc ttccaagaac catatttctc tccttcccac caattttccc ttgatgaggc     3780

tttagcagtt tgctcccacc acccccagcc catttcacaa ctctgatctt agtccaaagc     3840

aggggacacg cccccccacc accacttttt ctctctccca tctcagcctc ctgtgcagtt     3900

ccttgcctgc ccgtgcattt cctagagtct actgcctccc ccctggctgg gagggtgtct     3960

gggggggatc tttcaggggc cctggcaccc agggcctgtg ctggcctagg agtgctgacc     4020

agaaggctgc tctgttcccc cccacccccg ttgctttctg gccccctctt tggagccagc     4080

cacccacagg gctttggtgc ctcagaagca gtgggctgcc gggtcacagc cgcaggctgc     4140

aaaagaccct cggagggagc atggagtgag gggttctctc tcaggtgtgt atgtattggg     4200

gggtgggggt gggtggaggg tgtcagggaa gttggggtgg gatcccagcc ttcccttcaa     4260

gaggcaggga gctctgggag gtggagtccc caccgctttc tctactaggc tcctcctgtt     4320

ccccaggctt ggggagcttt gcacaaggag actgccccca gcctagtggc acctacctca     4380

tgggctctgg ggcaggtagg ggaagggcca gtccagctct ggtaatgctg gggggaggca     4440

taccaaagaa tccaggggca gggagtgggg agggtgactt ccgagctggc ctctcccctt     4500

cctctaccca gactggggct gggatcctct cctcccgctg taaccatttc tacctcattt     4560

tgctgcgtgt tgtacatgga cgtatttatc tcctgtctga cgatgctctg cagttgtggt     4620

ctgtctacct cagaagagac tgtattttaa aagaaagtat tacacagtat taaagcgatg     4680

acatgtggtt tgcaaaaaaa aaaaaaaaaa a                                    4711


<210>  1377
<211>  4277
<212>  DNA
<213>  homo sapiens

<400>  1377
ggagttcgcg cgacgaccgc ggggtcggcg ggcggggcga ggccctggac ggcggcggca       60

gtggggctcc tccttctgtt tcccagaccg agagccgcgc cggcaccatg tcagcttacc      120

ctaaaagcta caatccgttc gacgacgacg gggaggacga aggcgcccgg ccggcccctt      180

ggagggacgc ccgagacctc cccgacgggc ccgacgcgcc cgcggacagg cagcagtact      240

tgcggcagga ggtcctccgc agggctgagg ccacggccgc cagcaccagc aggtccctgg      300

ccctcatgta cgagtccgag aaggttgggg tcgcctcttc cgaggagctc gcccgtcagc      360

gaggagtcct ggagcgcaca gagaagatgg tggacaagat ggaccaagat ttgaagatca      420

gccagaaaca catcaatagc attaagagcg tgtttggggg gctggtcaat tacttcaaat      480

ccaaaccagt agagacccca cctgaacaga atggcaccct cacctcccag cccaacaaca      540

gattgaaaga agctataagt acaagtaaag aacaggaagc aaagtaccag gccagccacc      600

caaaccttag aaagctggat gatacagacc ctgtccccag aggggctggt tctgccatga      660

gtactgatgc ttacccaaag aacccacacc ttcgagccta tcaccagaag atcgacagca      720

acctagatga gctgtccatg ggactgggtc gtctgaagga catagccctg gggatgcaga      780

cagaaattga ggagcaagat gacattcttg accggctgac aaccaaagtg gacaagttag      840

atgtcaacat aaaaagcaca gaaagaaaag ttcgacaact ctgaagacag acggatttcc      900

actctattgt gatgaaaaga tttgaaagat ctttttttga acttccaaga aatttcattt      960

actattttag tatgtaaatt aatgtgtgtt tgcaaatgtt ataatagagt aggtcttaag     1020

acatttttgc tgttataagg aagtgtttgt cccacatttt cctagggtta acacctcacc     1080

aagttcttcc agcaaaatgc ttattagagt ttttgtctga gcacagtagc ctggccctgc     1140

atatcttggg cgtttgatta ccatgctgga ataagaagag ttgcatttct cattttaatg     1200

agcatatgga aagatgggaa cagaatttca gtcttgcagc catgagcctc tatttctcat     1260

tcctaagcct taccatgagt cagagtgtta agggggcctg tgaaccagtc gtttggtgga     1320

ggagggtcct tcccacacct ttgtttagga gtcatcattc acacacacac acacacacac     1380

acacacacac acacacacac acactctctg agcacattat ctgtgattct ttcatcctcc     1440

cagaaaggat cagtgttaga atgggaaata gagtgtgcca tcttgctctt ttgttggcag     1500

atgtccccgc ttccctccag ccccccatcc ttggcatgta tattagtagg agggcttcac     1560

accagcactg ctcactgcga ctcctggaaa tgtgtgggga attgggtgag cccctcttcc     1620

ccacgtgctc ccatctgtaa ctctccatct gtgatttgca acaggtcttc cactggctcg     1680

aggctgcgag gctgaccgac aggggcgccc aatagagttt gtgggaatgg agtattgcac     1740

agatgcagct gcacaatggt cttcctccac ccctctggga atcaccatta ggcaggcctc     1800

agtagggcaa aatgtttatt tggtaccggg ggtctcctga cctgtctagc attcccaccc     1860

actcttctgc acttcttgca aggtaacttg aatcatcact tatttctctg ccacctggtt     1920

ttaggactgg cactctataa atgacgctga ctttgtatag aaggattttg ctaagggggc     1980

aaaaagccca gataccattt taactggccc agttcatttt ctcctttcat tttacaaaag     2040

aaatcatgca gaagcatcaa ttaaaactga tttatttatg ttggtacatc caacaaaata     2100

gttggagcca caaggccctt gtctttttaa aaaaacaaaa tattttgaag atggtgaaag     2160

tgactgattt taataatgag ataggtcact taaaataaca gtgcctttga ccttaaaaca     2220

tggcactggc ccatgtgacc tttgccattt cccagtactt ccctttacag tctgcagcct     2280

ataaacagtg gtgtctcaaa gcaaaggaaa cctccacaag tgctgcaaca gtgcattagt     2340

ttttatgtag caatttgttt ataaaaattc ccatcccata atgcatgacc ttcctaaaaa     2400

tatccacagc ctccataggc aaggtgagct ttctgtgcta cccacttgtt agattccagc     2460

cacctcaggg attctgatcc atgtcattaa cgaccatccc agggtgtgag ggcctgatta     2520

aagcttatcg aactagacat ttgtttatta gatgagctcg gcattattat tttctcaata     2580

actggtagaa gggaaatttt aaacataaca ctcaacccaa acaaaactac ttcgtgaggc     2640

tttcagcaaa aaggctgctt aaaagcatga acccgggatg cagagcagct tttgtgcacg     2700

gttccactta ctgtaattgt ttctggttct ttcctctaac accttccatg tatgtcaact     2760

ttttatcacc gtcaggcata gactcgtgga gattagtcat tatagctcag acctaagcta     2820

attatttaaa ataaatacat gtaaaggcca ctgccacatt ctcagcagac ttccacttgc     2880

ctaatgagat tagtgattca actgacttga agcacagtaa catcttattt tatgcacatt     2940

ccctgtcttt tgctggactg atgaagccag tcacccgccc ttctctgttt tttggttttt     3000

tttttcttaa ccccaggtat atggaagggg agttgccttc acttttctgg aaatttgtct     3060

tcgtctgaca tattagaggg cctcgttttg tcctgttctt gttcagaccc tctcgttcta     3120

cgtcctgtgc tgaggggact gtccgtaagc tacaggacag cgagctggtc ctttctgcca     3180

cttcttcccc actcccatgc ccaggaaggc ctggttgctg atgctacttt ataaatgagt     3240

tgcttgcatt ttcacagaga atgaaggaag acgtaacatg gctccagaaa cttttcacat     3300

gatgattggg atcgacaaaa aaatgctacc ctctagacta gacacatttc atggagacaa     3360

gcaaaatggt gccagggctg ggctgactgt gggatgggat ttggtactgc agacagattt     3420

tgatttccac agttgagctg gaaacaaact gtgccttcaa aaaatgactt ttctaactta     3480

aggttggtta tatgttaagt gtgctactaa cttaaaaaat agtggctggg cgcggtggct     3540

catgcctgta atcccagtgc tttgggaggc caaggcgggg ggatcacgag gtcaggagat     3600

cgagaccatc ctggctaaca cggtgaaacc ccatctctac taaaaacaca caaaaaatta     3660

gctgggcgtg gtggtgggcg cctgtagtcc cagctactca ggaggctgag gcaggagaat     3720

ggcatgaacc tgggaggcag agcttgcagt gagccgagac agcgccattg cactccagcc     3780

tgggcaacag agcaagactc cgtctcaaaa aaaaaaaaaa aaaaaaaata gtgcactctc     3840

tggctggtca cggtggctca cgcctgtaat ctcagcactt tggaaggcca aggcaggcgg     3900

atcacgaggt cagaagatcg agaccatcct ggctaacaca gtgaaacccc gtctctacta     3960

aaaatataaa aaattagtcg ggcatggtgg cgggcgcctg tagtcccaac tactcgggag     4020

actgaggcag aagaatggcg tgaactcagg aggcggagct tgcagtgagc caaggcgaca     4080

gagcaagact ctgtctcaaa aaataaaaaa tagtgcactg tccttcgaga aagttttcta     4140

acatctagta atttgtaact tagaagtgga gttgccttgt ggatgtcttt tttgcattct     4200

gtaggaaatg aaacgtgaat ttaactcggg ttgcaagaaa taaaaatgtc agtgcattta     4260

aaaaaaaaaa aaaaaaa                                                    4277


<210>  1378
<211>  364
<212>  DNA
<213>  homo sapiens

<400>  1378
catgtctggg cgcggcaaag gcgggaaggg tctgggcaaa ggaggcgcta agcgccaccg       60

caaagttctg cgcgacaaca ttcagggcat caccaagccc gccatccgac gcctggcacg      120

gcgtggaggc gttaagcgca tctcaggcct tatatacgag gagacacgcg gagttcttaa      180

agtgtttttg gagaatgtaa tccgcgatgc agttacctac acggagcacg ccaaacgcaa      240

gacagtcaca gccatggacg tggtttacgc gctcaagcgc cagggccgca ccctgtatgg      300

ctttggcggc tgagtgtttt acttacttac acggttcctc aaaggccctt ctcagggcca      360

ccca                                                                   364


<210>  1379
<211>  356
<212>  DNA
<213>  homo sapiens

<400>  1379
atgtctggcc gcggcaaagg cgggaagggt cttggcaaag gcggcgctaa gcgccaccgt       60

aaagtactgc gcgacaatat ccagggcatc accaagccgg ccatccggcg ccttgctcgc      120

cgcggcggcg tgaagcgcat ctccggcctc atctacgagg agactcgcgg ggtgctgaag      180

gtgttcctgg agaacgtgat ccgggacgcc gtgacctata cagagcacgc caagcgcaag      240

acggtcaccg ccatggatgt ggtctacgcg ctcaagcgcc agggccgcac cctctacggt      300

ttcggtggtt gagcgtccct ttctatcaat aaaaggccct tttcagggcc acccta          356


<210>  1380
<211>  5747
<212>  DNA
<213>  homo sapiens

<400>  1380
atagagcttg ctgcctgtgt gagtgtgagg gggagagcga gagagagcaa gggagggaga       60

gagaggcagg ctgcgagggg agaggagagg gagtggggga gccagcgctc cagctagcat      120

gaggacgggc ttcttttccc gtgctcagtt aatctggctg tcagttggtg ttaacgctgc      180

agtttaagtg ttcggattcc aagggaaaca gacaaacctc acgaaaggaa ggaagcaagc      240

aagcaaggaa ggaactgcag gaggaaaaga acaggcagaa cagcgagaag aataaaggga      300

aaggggggga aacaccaaat ctatgattgg acctgggctt ctttttcgcc aatgcaaaaa      360

ggaatatgca gcacattttt gccttcttct gcaccggttt cctaggcgcg gtagtaggtg      420

ccaatttccc caacaatatc cagatcgggg gattatttcc aaaccagcag tcacaggaac      480

atgctgcttt tagatttgct ttgtcgcaac tcacagagcc cccgaagctg ctcccccaga      540

ttgatattgt gaacatcagc gacagctttg agatgaccta tagattctgt tcccagttct      600

ccaaaggagt ctatgccatc tttgggtttt atgaacgtag gactgtcaac atgctgacct      660

ccttttgtgg ggccctccac gtctgcttca ttacgccgag ctttcccgtt gatacatcca      720

atcagtttgt ccttcagctg cgccctgaac tgcaggatgc cctcatcagc atcattgacc      780

attacaagtg gcagaaattt gtctacattt atgatgccga ccggggctta tccgtcctgc      840

agaaagtcct ggatacagct gctgagaaga actggcaggt gacagcagtc aacattttga      900

caaccacaga ggagggatac cggatgctct ttcaggacct ggagaagaaa aaggagcggc      960

tggtggtggt ggactgtgaa tcagaacgcc tcaatgctat cttgggccag attataaagc     1020

tagagaagaa tggcatcggc taccactaca ttcttgcaaa tctgggcttc atggacattg     1080

acttaaacaa attcaaggag agtggcgcca atgtgacagg tttccagctg gtgaactaca     1140

cagacactat tccggccaag atcatgcagc agtggaagaa tagtgatgct cgagaccaca     1200

cacgggtgga ctggaagaga cccaagtaca cctctgcgct cacctacgat ggggtgaagg     1260

tgatggctga ggctttccag agcctgcgga ggcagagaat tgatatatct cgccggggga     1320

atgctgggga ttgtctggct aacccagctg ttccctgggg ccaagggatc gacatccaga     1380

gagctctgca gcaggtgcga tttgaaggtt taacaggaaa cgtgcagttt aatgagaaag     1440

gacgccggac caactacacg ctccacgtga ttgaaatgaa acatgacggc atccgaaaga     1500

ttggttactg gaatgaagat gataagtttg tccctgcagc caccgatgcc caagctgggg     1560

gcgataattc aagtgttcag aacagaacat acatcgtcac aacaatccta gaagatcctt     1620

atgtgatgct caagaagaac gccaatcagt ttgagggcaa tgaccgttac gagggctact     1680

gtgtagagct ggcggcagag attgccaagc acgtgggcta ctcctaccgt ctggagattg     1740

tcagtgatgg aaaatacgga gcccgagacc ctgacacgaa ggcctggaat ggcatggtgg     1800

gagagctggt ctatggaaga gcagatgtgg ctgtggctcc cttaactatc actttggtcc     1860

gggaagaagt tatagatttc tccaaaccat ttatgagttt ggggatctcc atcatgatta     1920

aaaaaccaca gaaatccaag ccgggtgtct tctccttcct tgatcctttg gcttatgaga     1980

tttggatgtg cattgttttt gcctacattg gagtgagtgt tgtcctcttc ctggtcagcc     2040

gcttcagtcc ctatgaatgg cacagtgaag agtttgagga aggacgggac cagacaacca     2100

gtgaccagtc caatgagttt gggatattca acagtttgtg gttctccctg ggagccttca     2160

tgcagcaagg atgtgacatt tctcccaggt ccctgtctgg tcgcatcgtt ggtggcgtct     2220

ggtggttctt caccttaatc atcatctcct catatacagc caatctggcc gccttcctga     2280

ccgtggagag gatggtgtct cccattgaga gtgcagagga cctagcgaag cagacagaaa     2340

ttgcctacgg gacgctggaa gcaggatcta ctaaggagtt cttcaggagg tctaaaattg     2400

ctgtgtttga gaagatgtgg acatacatga agtcagcaga gccatcagtt tttgtgcgga     2460

ccacagagga ggggatgatt cgagtgagga aatccaaagg caaatatgcc tacctcctgg     2520

agtccaccat gaatgagtac attgagcagc ggaaaccctg tgacaccatg aaggtgggag     2580

gtaacttgga ttccaaaggc tatggcattg caacacccaa ggggtctgcc ctgagaaatc     2640

cagtaaacct ggcagtgtta aaactgaacg agcaggggct tttggacaaa ttgaaaaaca     2700

aatggtggta cgacaagggc gagtgcggca gcgggggagg tgattccaag gacaagacaa     2760

gcgctctgag cctcagcaat gtggcaggcg tgttctacat cctgatcgga ggacttggac     2820

tagccatgct ggttgcctta atcgagttct gctacaaatc ccgtagtgaa tccaagcgga     2880

tgaagggttt ttgtttgatc ccacagcaat ccatcaacga agccatacgg acatcgaccc     2940

tcccccgcaa cagcggggca ggagccagca gcggcggcag tggagagaat ggtcgggtgg     3000

tcagccatga cttccccaag tccatgcaat cgattccttg catgagccac agttcaggga     3060

tgcccttggg agccacggga ttgtaactgg agcagatgga gaccccttgg ggagcaggct     3120

cgggctcccc agccccatcc caaacccttc agtgccaaaa acaacaacaa aatgaaacgc     3180

aaccaccacc aaccactgcg accacaagaa ggatgattca acaggttttc ctgaagaatt     3240

gaaaaaccat tttgctgtcc cttttccttt tttgatgttc tttcaccctt ttctgtttgc     3300

taagtgagga tgaaaaaata acactgtact gcaataaggg gagagtaacc ctgtctaatg     3360

aaacctgtgt ctctgagagt agagtcactg gaacactaat gaggaaactg cactgtttta     3420

ttttaattca gttgttagtg tgtcttagtg tgtgcaattt tttttcttac taatatccat     3480

ggtttgcagg ttctgttagg ccctttcctt ctccttactt cttatcccca actccctacc     3540

cacccctctt cagttttcag attggagatt caagatttgt tccactttac aagcaagagg     3600

aaaaaaaagc aaccttcaaa ctaattctcc atgggggctc tccatgttac cctccactcc     3660

ttggcccaaa cctctgatgg agatagacat tgttggagaa gtgggctgcc ttccccaagt     3720

ggggcactgc ttaagcactt attcagtgga gaacacaggt gaaaagcaac tcaggatgag     3780

ggtggtggag agggcagggg cagatgtgca gtcagagaag gactcctgaa gttactgctg     3840

ctcagaaaaa cagttccttt aatgtggaag agccatttca taggtcatag gtggtatggt     3900

atatttcttc agagtcaacc ttggccctga gaagtatgtc ctcctggtgt gctcaggctc     3960

aacggcagtc tggtggctga aggcacttgg cctcctaaac caagcagaat tttgggaaga     4020

gataacagcc agggagatat tgcccatgat tctcactttt tctttgcctg gcatctaagc     4080

aggaacccat tgtggagtag actctcttct tctatggagc ctctgacatg gggagcaatg     4140

ctaagcaagc taagtgtaaa agaaaagtga cagaataatt ttggaagagg aagcctcatc     4200

aaaagctcac acaaaataga gcttcccatg gtgtgcccta tcctaggttt aagaaaacac     4260

gtatgaagtt tatgctgatg caaagaactt gggtttttat gttaatataa agtgttgttt     4320

tagcatgtgg ccagatgatg ctctgtcatc tttagaaagt gagataacca aggaaataat     4380

tgaaggagta tagggagatg gattaagttg ataatgacat ttagggcaac ttaagacctt     4440

tgatcccagg ttctaactca aagaggctga ccttccccca gctaagatag catgaggacg     4500

ttgtattcca atatacgtat gattggggct acaaagctga actaaagcaa gattggtgaa     4560

gtggcagggt ttatagagag aagcccaggc tgagttcagc ttttgttgga agtgagaatc     4620

cctgacatat agctttcttg gagatcccaa ctctcattct tggtgcaact ggcttccagc     4680

tctccagcag tcactctcct aggtgcatga ttcagtgcgt gccatgtgtc attagctttt     4740

actgataacc atattctggc ttgttccctt accccctact tctatccaat tttctctgct     4800

aggggttatc attagcaatt gacatgctaa aggttttgga gcccacctag gggtaggtgc     4860

agctttattg gcttttctgt ggattctctc agtggaccca caccatctct atgtctctcc     4920

actctcctgc cttcagccat agcaaagaat ccttccaaaa tcaaactctt cacttttttg     4980

actcaagtgt tgttgttcag tctctcgcgt gtcaatgtgg tcatggttca tgaaaccgga     5040

ccctcaagat ggatgattgc ttttaactac tgccagctga tgtctctcag cccctgccct     5100

catacaagat ttttctcagc cttcagccta ccactgcaga atccgatgtg acccaccatt     5160

agggagtctg catcttggaa gagttggaaa taacccttta acatcaacat gcttcaaaga     5220

ctttttgcct ttggcctagt aagatgcctc tccagctact gagcccacaa gtaacatgag     5280

cggataaaaa gagacttgtt tgtgctagaa atgagggtct atgctatgag ggggtccaag     5340

actctggcga aatgtgcttt ttcatcaatg gagaaatgaa aggaaaacac aagcaagaaa     5400

aaagttaact tgtattatgt atttttacta cacttttctt aaaaatagag cattgggaaa     5460

actctgaaag agactgacat ttttctcaac aggaatccat acttaacagt tctggctttc     5520

attaaatttt gctctttggt acctgggcct tttatttaac atctatattt gttttaactc     5580

tcttggcaga tgtgtgaaag gattcttgct tgatcaaaca ctaagtattt ttttggttct     5640

tgtttttctt tcaaatagcc aggttttttt cttttggtat ttgcataaaa tgaaaatatc     5700

accgaatatt aaatcactgt ggatccatta aaaaaaaaaa aaaaaaa                   5747


<210>  1381
<211>  5747
<212>  DNA
<213>  homo sapiens

<400>  1381
atagagcttg ctgcctgtgt gagtgtgagg gggagagcga gagagagcaa gggagggaga       60

gagaggcagg ctgcgagggg agaggagagg gagtggggga gccagcgctc cagctagcat      120

gaggacgggc ttcttttccc gtgctcagtt aatctggctg tcagttggtg ttaacgctgc      180

agtttaagtg ttcggattcc aagggaaaca gacaaacctc acgaaaggaa ggaagcaagc      240

aagcaaggaa ggaactgcag gaggaaaaga acaggcagaa cagcgagaag aataaaggga      300

aaggggggga aacaccaaat ctatgattgg acctgggctt ctttttcgcc aatgcaaaaa      360

ggaatatgca gcacattttt gccttcttct gcaccggttt cctaggcgcg gtagtaggtg      420

ccaatttccc caacaatatc cagatcgggg gattatttcc aaaccagcag tcacaggaac      480

atgctgcttt tagatttgct ttgtcgcaac tcacagagcc cccgaagctg ctcccccaga      540

ttgatattgt gaacatcagc gacagctttg agatgaccta tagattctgt tcccagttct      600

ccaaaggagt ctatgccatc tttgggtttt atgaacgtag gactgtcaac atgctgacct      660

ccttttgtgg ggccctccac gtctgcttca ttacgccgag ctttcccgtt gatacatcca      720

atcagtttgt ccttcagctg cgccctgaac tgcaggatgc cctcatcagc atcattgacc      780

attacaagtg gcagaaattt gtctacattt atgatgccga ccggggctta tccgtcctgc      840

agaaagtcct ggatacagct gctgagaaga actggcaggt gacagcagtc aacattttga      900

caaccacaga ggagggatac cggatgctct ttcaggacct ggagaagaaa aaggagcggc      960

tggtggtggt ggactgtgaa tcagaacgcc tcaatgctat cttgggccag attataaagc     1020

tagagaagaa tggcatcggc taccactaca ttcttgcaaa tctgggcttc atggacattg     1080

acttaaacaa attcaaggag agtggcgcca atgtgacagg tttccagctg gtgaactaca     1140

cagacactat tccggccaag atcatgcagc agtggaagaa tagtgatgct cgagaccaca     1200

cacgggtgga ctggaagaga cccaagtaca cctctgcgct cacctacgat ggggtgaagg     1260

tgatggctga ggctttccag agcctgcgga ggcagagaat tgatatatct cgccggggga     1320

atgctgggga ttgtctggct aacccagctg ttccctgggg ccaagggatc gacatccaga     1380

gagctctgca gcaggtgcga tttgaaggtt taacaggaaa cgtgcagttt aatgagaaag     1440

gacgccggac caactacacg ctccacgtga ttgaaatgaa acatgacggc atccgaaaga     1500

ttggttactg gaatgaagat gataagtttg tccctgcagc caccgatgcc caagctgggg     1560

gcgataattc aagtgttcag aacagaacat acatcgtcac aacaatccta gaagatcctt     1620

atgtgatgct caagaagaac gccaatcagt ttgagggcaa tgaccgttac gagggctact     1680

gtgtagagct ggcggcagag attgccaagc acgtgggcta ctcctaccgt ctggagattg     1740

tcagtgatgg aaaatacgga gcccgagacc ctgacacgaa ggcctggaat ggcatggtgg     1800

gagagctggt ctatggaaga gcagatgtgg ctgtggctcc cttaactatc actttggtcc     1860

gggaagaagt tatagatttc tccaaaccat ttatgagttt ggggatctcc atcatgatta     1920

aaaaaccaca gaaatccaag ccgggtgtct tctccttcct tgatcctttg gcttatgaga     1980

tttggatgtg cattgttttt gcctacattg gagtgagtgt tgtcctcttc ctggtcagcc     2040

gcttcagtcc ctatgaatgg cacagtgaag agtttgagga aggacgggac cagacaacca     2100

gtgaccagtc caatgagttt gggatattca acagtttgtg gttctccctg ggagccttca     2160

tgcagcaagg atgtgacatt tctcccaggt ccctgtctgg tcgcatcgtt ggtggcgtct     2220

ggtggttctt caccttaatc atcatctcct catatacagc caatctggcc gccttcctga     2280

ccgtggagag gatggtgtct cccattgaga gtgcagagga cctagcgaag cagacagaaa     2340

ttgcctacgg gacgctggaa gcaggatcta ctaaggagtt cttcaggagg tctaaaattg     2400

ctgtgtttga gaagatgtgg acatacatga agtcagcaga gccatcagtt tttgtgcgga     2460

ccacagagga ggggatgatt cgagtgagga aatccaaagg caaatatgcc tacctcctgg     2520

agtccaccat gaatgagtac attgagcagc ggaaaccctg tgacaccatg aaggtgggag     2580

gtaacttgga ttccaaaggc tatggcattg caacacccaa ggggtctgcc ctgagaggtc     2640

ccgtaaacct agcggttttg aaactcagtg agcaaggcgt cttagacaag ctgaaaagca     2700

aatggtggta cgataaaggg gaatgtggaa gcaaggactc cggaagtaag gacaagacaa     2760

gcgctctgag cctcagcaat gtggcaggcg tgttctacat cctgatcgga ggacttggac     2820

tagccatgct ggttgcctta atcgagttct gctacaaatc ccgtagtgaa tccaagcgga     2880

tgaagggttt ttgtttgatc ccacagcaat ccatcaacga agccatacgg acatcgaccc     2940

tcccccgcaa cagcggggca ggagccagca gcggcggcag tggagagaat ggtcgggtgg     3000

tcagccatga cttccccaag tccatgcaat cgattccttg catgagccac agttcaggga     3060

tgcccttggg agccacggga ttgtaactgg agcagatgga gaccccttgg ggagcaggct     3120

cgggctcccc agccccatcc caaacccttc agtgccaaaa acaacaacaa aatgaaacgc     3180

aaccaccacc aaccactgcg accacaagaa ggatgattca acaggttttc ctgaagaatt     3240

gaaaaaccat tttgctgtcc cttttccttt tttgatgttc tttcaccctt ttctgtttgc     3300

taagtgagga tgaaaaaata acactgtact gcaataaggg gagagtaacc ctgtctaatg     3360

aaacctgtgt ctctgagagt agagtcactg gaacactaat gaggaaactg cactgtttta     3420

ttttaattca gttgttagtg tgtcttagtg tgtgcaattt tttttcttac taatatccat     3480

ggtttgcagg ttctgttagg ccctttcctt ctccttactt cttatcccca actccctacc     3540

cacccctctt cagttttcag attggagatt caagatttgt tccactttac aagcaagagg     3600

aaaaaaaagc aaccttcaaa ctaattctcc atgggggctc tccatgttac cctccactcc     3660

ttggcccaaa cctctgatgg agatagacat tgttggagaa gtgggctgcc ttccccaagt     3720

ggggcactgc ttaagcactt attcagtgga gaacacaggt gaaaagcaac tcaggatgag     3780

ggtggtggag agggcagggg cagatgtgca gtcagagaag gactcctgaa gttactgctg     3840

ctcagaaaaa cagttccttt aatgtggaag agccatttca taggtcatag gtggtatggt     3900

atatttcttc agagtcaacc ttggccctga gaagtatgtc ctcctggtgt gctcaggctc     3960

aacggcagtc tggtggctga aggcacttgg cctcctaaac caagcagaat tttgggaaga     4020

gataacagcc agggagatat tgcccatgat tctcactttt tctttgcctg gcatctaagc     4080

aggaacccat tgtggagtag actctcttct tctatggagc ctctgacatg gggagcaatg     4140

ctaagcaagc taagtgtaaa agaaaagtga cagaataatt ttggaagagg aagcctcatc     4200

aaaagctcac acaaaataga gcttcccatg gtgtgcccta tcctaggttt aagaaaacac     4260

gtatgaagtt tatgctgatg caaagaactt gggtttttat gttaatataa agtgttgttt     4320

tagcatgtgg ccagatgatg ctctgtcatc tttagaaagt gagataacca aggaaataat     4380

tgaaggagta tagggagatg gattaagttg ataatgacat ttagggcaac ttaagacctt     4440

tgatcccagg ttctaactca aagaggctga ccttccccca gctaagatag catgaggacg     4500

ttgtattcca atatacgtat gattggggct acaaagctga actaaagcaa gattggtgaa     4560

gtggcagggt ttatagagag aagcccaggc tgagttcagc ttttgttgga agtgagaatc     4620

cctgacatat agctttcttg gagatcccaa ctctcattct tggtgcaact ggcttccagc     4680

tctccagcag tcactctcct aggtgcatga ttcagtgcgt gccatgtgtc attagctttt     4740

actgataacc atattctggc ttgttccctt accccctact tctatccaat tttctctgct     4800

aggggttatc attagcaatt gacatgctaa aggttttgga gcccacctag gggtaggtgc     4860

agctttattg gcttttctgt ggattctctc agtggaccca caccatctct atgtctctcc     4920

actctcctgc cttcagccat agcaaagaat ccttccaaaa tcaaactctt cacttttttg     4980

actcaagtgt tgttgttcag tctctcgcgt gtcaatgtgg tcatggttca tgaaaccgga     5040

ccctcaagat ggatgattgc ttttaactac tgccagctga tgtctctcag cccctgccct     5100

catacaagat ttttctcagc cttcagccta ccactgcaga atccgatgtg acccaccatt     5160

agggagtctg catcttggaa gagttggaaa taacccttta acatcaacat gcttcaaaga     5220

ctttttgcct ttggcctagt aagatgcctc tccagctact gagcccacaa gtaacatgag     5280

cggataaaaa gagacttgtt tgtgctagaa atgagggtct atgctatgag ggggtccaag     5340

actctggcga aatgtgcttt ttcatcaatg gagaaatgaa aggaaaacac aagcaagaaa     5400

aaagttaact tgtattatgt atttttacta cacttttctt aaaaatagag cattgggaaa     5460

actctgaaag agactgacat ttttctcaac aggaatccat acttaacagt tctggctttc     5520

attaaatttt gctctttggt acctgggcct tttatttaac atctatattt gttttaactc     5580

tcttggcaga tgtgtgaaag gattcttgct tgatcaaaca ctaagtattt ttttggttct     5640

tgtttttctt tcaaatagcc aggttttttt cttttggtat ttgcataaaa tgaaaatatc     5700

accgaatatt aaatcactgt ggatccatta aaaaaaaaaa aaaaaaa                   5747


<210>  1382
<211>  6839
<212>  DNA
<213>  homo sapiens

<400>  1382
cggcagctgt cccgcctgcc acaatgcgcg gcgaagctgc ggccgcgact tggcgaggtg       60

gtccctaacg ttgccgctcg gcatccttag aaccggccgc ccctgacgcc gcgcggggac      120

cccagtcgcc cgcgcgcccc atgcgctcac tcttcggtgc ccggccgggc cggcgcctcg      180

cagacgcgga gccgcgcggg tgacggcaca ggcggctgcg cgcccagccc agcccagccc      240

agcccgagga gagggcgcgc cgcgcccccg ccccccgccc gctctcccga ggccgtgggt      300

gcggatgcgc ggctgacgac tcgcagcaag agcaccgccg ccggccccag cccgcagcat      360

ggcagccgcc gcctatgtgg accacttcgc cgccgagtgc ctcgtgtcca tgtcgagccg      420

cgcggtcgtg cacgggccgc gggaggggcc ggagtcccgg cccgagggcg cggccgtggc      480

cgccaccccc acgctgcccc gcgtcgagga gcgccgcgac ggtaaggaca gcgcctcgct      540

cttcgtggtg gcgcggatcc tagcggacct caaccagcaa gcgccggcgc ccgccccggc      600

ggagcgcagg gagggcgccg cggcccggaa ggcgaggacc ccctgccgcc tgccgccgcc      660

cgcccccgag cccacctccc ccggcgccga aggcgcggcg gccgcgcccc ccagcccggc      720

gtggagcgag ccggagcccg aggcggggct ggagcccgag cgggagccgg ggcccgcggg      780

gagcggcgag cccggcctca gacaaagggt ccggcggggc cgaagtcgcg ccgacctcga      840

gtccccgcag aggaagcaca agtgccacta cgcgggctgc gagaaagttt acgggaaatc      900

ttcgcacctc aaggcgcacc tgagaactca cacaggtgag aggcccttcg cctgcagctg      960

gcaggactgc aacaagaagt tcgcgcgctc cgacgagctg gcgcggcact accgcacaca     1020

cacgggcgag aagaagttca gctgccccat ctgcgagaag cgcttcatgc gcagcgacca     1080

cctgaccaag cacgcgcgcc gccacgccaa cttccacccg ggaatgctgc agcggcgcgg     1140

cgggggctcg cggaccggct ccctcagcga ctacagccgc tccgacgcca gcagccccac     1200

catcagcccg gccagctcgc cctgagcccg ccacagccat gagcagccgc tcccaccccc     1260

tcgtgagtcc ctggcctttc cttttgtaat aagaaagaag agagagaact tgatgcaaag     1320

tccacgaaaa aacaattttt ttcacctcag gtgtcaaagt aaatttgtta aaaaaacaaa     1380

aaaaacacaa aaatttcaaa aaacaccacc caccaaattg cacaatagat acacccacaa     1440

agttgagatt cagcgttgtt gaaccccctt tctcagggat ggacacgttt cacgaggtca     1500

gtgaggacac cccttcctgc cgccttactc tgtacataga tttgcactct ggagttttct     1560

gttaggttcg ggaacacgct ggggacagag caggccagcc agtctggtgg agctcagcgt     1620

ctggctggct ggccagcctg tgggtctgtt gggagcagat gtgctcactg acgtttgtgc     1680

ctccagggca gattcctaag cagctggcct gacctcttcc tgcccagccc ccaacccagt     1740

ctctggcctc tgcccaacga gcctggctgg gcttgcaacg cagctgattc tgagacaggc     1800

ccctgcagag ggatgcctta aagctgtccc tggctggagg agcactccac cttggggata     1860

gtggaggggg ccttcagccc tctgcaccct gcctgcctca caccccgcct tcaggagccc     1920

tctcctacgg cgctagggag cactggaagc agagatgcca gccctggctg agcgtagcac     1980

tgcaccgtcc gacctccgag gcaggggccg gggtcacacc tgccaggact ccgcttctcc     2040

gtgtcccagc agaaggcatg caggaccctg tcactactat acctgggcct ctgatgggga     2100

attctggtct tctaaaaaga tgttagaaat tcctggtggc acatccagtt ccgagtttgc     2160

ccgcacgggc acttttgttg gaaacagtgg gcaggtcatg gggcctcctc atcagagggt     2220

ctgtgtgagc ggctgtgcat gtggcagcgc accatgcttc acagagacca ttctgtagca     2280

agagaccgga acattgtgac ttggaccttt tcaggagtgg cgcggatgtt acaggaaatg     2340

ctgtcggaga gcgcgcattc tatttcctcc gcagggaatg ccagatagaa agttgcgggc     2400

aacacttttc tcagacccac catgtcccca actcagactt agcaaacctc cagcctctcc     2460

gtttcccctg gactcctcct cccttttcct cctgcttctc cttgtcctgc ctggaggctc     2520

caggccacac ccagctggtg gggctgctcc agtgccccat caccggcctt ctcctggcag     2580

gagaggagga gcagagagct gggtcctggg ctgggattcg agccctgggc gggggtcagt     2640

caagccgtgg tccagcaaac tcctctgcag atggctggag tgttgaccca ggcttgtggc     2700

ccaggtatca ccttcccttc ctcctgagag ttgaggcctg taaatacaag ggcccaggac     2760

agagtgtgtg cgtgcgtgtg ggtgtgtgcg cgcgtgagca cacacgcgtg tgttgggggg     2820

ggtgggggga ttggggtgga ctcagggtat cttgccagag atacctgttt tgatgagtac     2880

ctattttgat gcaaaggaac ggccctggga cctcagaggg ccacagatgg gcttcctggg     2940

cctagcgtgc cttggttgtg gccatcctgc ttctactcag ccctgccatg ctatggggtg     3000

cagcacaaac ccaggaccca ggcctagcca ctgcccacag ctgatggtca ctgttttggc     3060

tggctccaga gtggacaggt acgctctgtc cacagcagct gctcaggcac agtatgccgt     3120

caggtgcccg cttcttacca ctgtgtgtca gctgggattg gccgacagcg tggtggtgac     3180

ttctaggtag accgatggac cctaaattgg gcagtggcat tgtttctgct gtggtgggaa     3240

ctggcaggga gagggtcacc tccactctgg ttggatgcgg agctggtccc tctggctgcc     3300

atgctgtgtt ggggctctct gacctccctg cttgcattgg gtctgggaga gagagtggaa     3360

tatttggtag ggaccttgac agaagagagc cctgggtgct tgtggtgcaa agatcttcat     3420

gcccagttcc aaagtgaggt ccctcccaaa gttgttttcg tgtgaggcag agaaagccac     3480

actctgaata cattttatgt ctcaggaatt cacattccag gttcaggaat tttattccaa     3540

agtcctttgg tgcactcacc gtccaccgtt ccccaaggca gggagaggga gtggcccgtc     3600

cctgggaggc tggcaaagtg ctctccaggg aggggtcaga cgtccttgtg atctgcccag     3660

ggtgtcacgg aaggagattt tctagctcca catctgtctg cacataggaa ggaaaagata     3720

ggactctaaa cctagtcatc ttggaataaa aagaagagct ggtttgtttt agagcagggc     3780

ggggggtggg ggagggaagc gggtgttggc tgtttccaaa gagagcactt aatttaattt     3840

ttcctttaaa tgacccaggg ctgttccgtc tgatagatgg aagggtaaca ttgccttaaa     3900

acagaaatat gcaggcgttg gctatttttg gcataagagc gtgtcttcat tcccaaagtg     3960

gttctcgttt aatggcaggg tgcggtcctt aggccccggc ctggactggg aaatgggggt     4020

agggcaccag gagagaaatc ctcctgggta ctcctggcca gaccctcctg aatcatctgc     4080

ggcttaaact catctcgctt gaagggcagg gagaaaccca tgaatctcag gcacggttca     4140

caggggtcct caagggcagg tttccatttc atcatgaagt gagggactcc tgtggaagag     4200

ggtggtgggc cttggaacgc tgcctccact gaggcgggca cacaaggcgg accctcctga     4260

aacagcctcc attttcttca aacatgcaga atgttttccc agactgcgtc tatttcaggg     4320

tcttccattt ttgtggttta tggccatgct tgccagtttt ggtggggttg aggaacccat     4380

aggactcata gaaataatag tgaaaactca aacccttatt ttgggacttc agttctcgtg     4440

gtccataggg gcagagatgt caaagtgaag gttgcctgag tgaagggaga gttcccctat     4500

aaaaggccta aaattgatct ggggctcagc catcaagggg ctggtgttgc tcctgtccca     4560

gacaaggaag cccctcttta catcagccat attaggggaa cggttgtcag ctccccaaat     4620

gcctactgga tcctacagcc atacaggaaa acagacggac acagcccttt ccttaaagag     4680

ccctggggtc ctgtcctgca ggatgctgca taggaatggg cagagatgtc ctggatggga     4740

acatggtcct ggaggtgccc tacctgcatc ctgctgcacc cccacccacg acactcgagt     4800

gcaagatcgc ctcactccta accctgactt tattcccagg ccccacaccg aggcaggtgc     4860

aggattcgcc atggtgcagc ctccgggtac aaacatctga ggcactggcg atcccagtcc     4920

ttgcagcacc ctgaacacag ctcagaccag tgaggggtga ttcagaggtg gggatgggca     4980

gagagggctg gccactctgc ctcaggactt gacctcaagt gttctgtctc cccacccggt     5040

gtgtccagaa gaccagcctc tttcttgcca gaagcaggtg ctaagatgga ctgcacaggg     5100

tcccggcact ccctcgggac ccattcagga tctcagctgg gcaggggtgc cacccaacag     5160

gaagatgtga tctgagcaat agtgtggcct tgtttctccg cttctggttg tggctgtgtg     5220

tacagggcta cctattttga cttctgacag gtgtcactga ttttctttcc cccatttaaa     5280

aaaggtcatt tagtcaaaga cacagtgcta gaggtttaaa gggtgtaatg tgttggtcac     5340

atcacaacca gtaagaaacg cttggtaggt tatccacatc ttttgctgac tgtttccata     5400

tacaattctg gtcaccatat tttccaaagc taaaatctga ggcgtgggct gatggttttt     5460

gaaatcagga ttaccccagg aagaaccagg tcctattact aattttcctg attctgaggc     5520

tctgaaggct tgtctgagac acattccgga gacctttgta ccagaacttg gatgcatagt     5580

ccaccttact actgatacac gcctgagcac cctttagggc gaggcgccgc ctcctgcctg     5640

ctgtcctgtc cctcagcatc agaagagttg aattcagcag gagacgggag cccggtgtcc     5700

atgagggaag aggggtcgcg cttggtttct actgaccccc atgaagattt cagacttgca     5760

gtgcggccac ctggccctgc cctgcctctc tctttctcat acagctttaa aactttacta     5820

cttttattta aaaatgaact ggatgggaga gaagtagcgt cccctaccct acaagtcaca     5880

cattccgggg aggggggtgg ggggtggagg caggaagtca tgggggtggg ggtgggagca     5940

cgggaacagc tttcttaagg cctcagggtc ctgttttccc tggcctcttc tagagggccc     6000

gtggacaggt cgcagtgcgt gcttatttgg aaaccaggtg tgtgagccga atgcctgcca     6060

ggccatgcac tcagcagagg agcccttgta cctggctgcc ctgagaggag caagaggcca     6120

cctcccatgt ggctctagac accacgtggg ctcattagcc ccagcgtctg tgccggctcc     6180

aggtgcctgc ctctgggtgt gtgagtggga gactttgctc cctggcctca tcctagagag     6240

gcccctggtg cctagtgctg aggcctctgg ggctggaaag cctcagcaga aaggaggcac     6300

tactgagcaa ctatgcattg tcattgtcgg gtttggggct ttcggtggtt ccttggtgac     6360

tgggaattgc ttgtgtgcat gtgttgggtg catgcttccg ggtctcagct gccccaggcc     6420

cgcacaggca accccttccc atccaaagcc attggtggag cttctctgga atcatttgcc     6480

aaaagcccaa ggcagaatcc aagggtccaa gaccatttcc atggagctca tgtttttctt     6540

ttctgtagga actttttttt aaccagcacc caccataatt ccgaaggcca cgtttcatct     6600

ttcctggatc actacagtga agtattacag ttgtacagtt cccagtctgg ccttggcttg     6660

ctcggataaa actttgtatg tattttgtat ggcatagatt ctatattgta atgatgtcct     6720

atgcaaaaag aaaaattaac gaaattgtaa attttattgt tttaacgtgt atgcatgttt     6780

agtgacgttt acattttgaa ataaaattta tgattcatta ttttaaaaaa aaaaaaaaa      6839


<210>  1383
<211>  5935
<212>  DNA
<213>  homo sapiens

<400>  1383
cttttcccat cgtgtagtca agagtctgtg ccagacttga aggctttact ttgttagcca       60

tgtgtttatg aacccccagc gctttcccta gatcttttgg ctgataatct caaacatgga      120

ggatgcttct gaatcttcac gaggggttgc tccattaatt aataatgtag ttctcccagg      180

ctctccgctg tctcttcctg tatcagtgac aggctgtaaa agtcatcgag tagccaataa      240

aaaggtagaa gcgaggagtg aaaagctcct cccaacagct cttcctcctt cagagccgaa      300

agtagatcag aaacttccca ggagctccga gaggcgggga agtggcggtg ggacgcaatt      360

ccccgcgcgg agtcgggcag tggcagcggg agaagcggca gccaggggcg cggcggggcc      420

ggagagaggc ggtcccctgg gaggacgggg tctcccctcg ttgcctttgt agtggagaag      480

gtggacaagt ggcagtcggc gtgatcgcag ggaagcgggg ccggcgcggg cggccgaggg      540

tccaggcgag cccgcgggcg gacgggagat gccgctgcta caccgaaagc cgtttgtgag      600

acagaagccg cccgcggacc tgcggcccga cgaggaagtt ttctactgta aagtcaccaa      660

cgagatcttc cgccactacg atgacttttt tgaacgaacc attctgtgca acagccttgt      720

gtggagttgt gctgtgacgg gtagacctgg actgacgtat caggaagcac ttgagtcaga      780

aaaaaaagca agacagaatc ttcagagttt tccagaacca ctaattattc cagttttata      840

cttgaccagc cttacccatc gttcgcgctt acatgaaatt tgtgatgata tctttgcata      900

tgtcaaggat cgatattttg tcgaagaaac tgtggaagtc attaggaaca atggtgcaag      960

gttgcagtgt aggattttgg aagtcctccc tccatcacat caaaatggtt ttgctaatgg     1020

acatgttaac agtgtggatg gagaaactat tatcatcagt gatagtgatg attcagaaac     1080

acaaagctgt tcttttcaaa atgggaagaa aaaagatgca attgatccct tactattcaa     1140

gtataaagtg caacccacta aaaaagaatt acatgagtct gctattgtta aagcaacaca     1200

aatcagccgg agaaaacacc tattttctcg tgataaacta aagctttttc tgaagcaaca     1260

ctgtgaacca caagatggag tcattaaaat aaaggcatca tctctttcaa cgtataaaat     1320

agcagaacaa gatttttctt atttcttccc tgatgatcca cccacattta tcttcagtcc     1380

tgctaacaga cgaagaggga gacctcccaa acgaatacat attagtcaag aggacaatgt     1440

tgctaataaa cagactcttg caagttatag gagcaaagct actaaagaaa gagataaact     1500

tttgaaacaa gaagaaatga agtcactggc ttttgaaaag gctaaattaa aaagagaaaa     1560

agcagatgcc ctagaagcga agaaaaaaga aaaagaagat aaagagaaaa agagggaaga     1620

attgaaaaaa attgttgaag aagagagact aaagaaaaaa gaagaaaaag agaggcttaa     1680

agtagaaaga gaaaaggaaa gagagaagtt acgtgaagaa aagcgaaagt atgtggaata     1740

cttaaaacag tggagtaaac ctagagaaga tatggaatgt gatgacctta aggaacttcc     1800

agaaccaaca ccagtgaaaa ctagactacc tcctgaaatc tttggtgatg ctctgatggt     1860

tttggagttc cttaatgcat ttggggaact ttttgatctt caagatgagt ttcctgatgg     1920

agtaacccta gaagtattag aggaagctct tgtaggaaat gacagtgaag gcccactgtg     1980

tgaattgctt tttttcttcc tgactgcaat cttccaggca atagctgaag aagaagagga     2040

agtagccaaa gagcaactaa ctgatgctga caccaaaggc tgcagtttga aaagtttgga     2100

tcttgatagc tgcactcttt cagaaatcct cagactgcac atcttagctt caggtgctga     2160

tgtaacatca gcaaatgcaa agtatagata tcaaaaacga ggaggatttg atgctacaga     2220

tgatgcttgt atggagcttc gtttgagcaa tcccagtcta gtgaagaaac tgtcaagcac     2280

ctcagtgtat gatttgacac caggagaaaa aatgaagata ctccatgctc tctgtggaaa     2340

gctactgacc ctagtttcaa ctagggattt tattgaagat tatgttgata tattacgaca     2400

ggcaaagcag gagttccggg aattaaaagc agaacaacat cgaaaagaga gggaagaagc     2460

agctgccaga attcgtaaaa ggaaggaaga aaaacttaag gagcaagaac aaaaaatgaa     2520

agagaaacaa gaaaaactga aagaagatga gcaaagaaat tcaacggcag atatatctat     2580

tggggaggaa gaaagggaag attttgatac tagcattgag agcaaagaca cagagcaaaa     2640

ggaattagat caagatatgg tcactgaaga tgaagatgac ccaggatcac ataaaagagg     2700

cagaaggggg aaaagaggac aaaatggatt taaagaattt acaaggcaag aacagatcaa     2760

ctgtgtaaca agagagcctc ttactgctga tgaggaagaa gcattaaaac aggaacacca     2820

acgaaaagag aaagagctct tagaaaaaat ccaaagtgcc atagcctgta ccaatatctt     2880

tcccttgggt cgcgaccgca tgtatagacg atactggatt ttcccttcta ttcctggact     2940

ctttattgaa gaggattatt ctggtcttac tgaagacatg ctgttgccta gaccttcatc     3000

atttcagaat aatgtacagt ctcaagatcc tcaggtatcc actaaaactg gagagccttt     3060

gatgtctgaa tctacctcca acattgacca aggtccacgt gaccattctg tgcagctgcc     3120

aaaaccagtg cataagccaa atcggtggtg cttttacagt tcttgtgaac agctagacca     3180

gcttattgaa gctcttaatt ctagaggaca tagagaaagt gccttaaaag aaactttgtt     3240

acaagagaaa agcagaatat gtgcacagct agcccgtttt tctgaagaga aatttcattt     3300

ttcagacaaa cctcagcctg atagcaaacc aacatatagt cggggaagat cttccaatgc     3360

atatgatcca tctcagatgt gtgcagaaaa gcaacttgaa ctaaggctga gagattttct     3420

tttagatatt gaagatagaa tctaccaagg aacattagga gccatcaagg ttacagatcg     3480

acatatctgg agatcagcat tagaaagtgg acggtatgag ctgttaagtg aggaaaacaa     3540

ggaaaatggg ataattaaaa ctgtgaatga agacgtagaa gagatggaaa ttgatgaaca     3600

aacaaaggtc atagtaaaag acagactttt ggggataaaa acagaaactc caagtactgt     3660

atcaacaaat gcaagtacac cacaatcagt gagcagtgtg gttcattatc tggcaatggc     3720

actctttcaa atagagcagg gcattgagcg gcgttttctg aaagctccac ttgatgccag     3780

tgacagtggg cgttcttata aaacagttct ggaccgttgg agagagtctc tcctttcttc     3840

tgctagtcta tcccaagttt ttcttcacct atccaccttg gatcgtagcg tgatatggtc     3900

taaatctata ctgaatgcgc gttgcaagat atgtcgaaag aaaggcgatg ctgaaaacat     3960

ggttctttgt gatggctgtg ataggggtca tcatacctac tgtgttcgac caaagctcaa     4020

gactgtgcct gaaggagact ggttttgtcc agaatgtcga ccaaagcaac gttctagaag     4080

actctcctct agacagagac catccttgga aagtgatgaa gatgtggaag acagtatggg     4140

aggtgaggat gatgaagttg atggcgatga agaagaaggt caaagtgagg aggaagagta     4200

tgaggtagaa caagatgaag atgactctca agaagaggaa gaagtcagcc tacccaaacg     4260

aggaagacca caagttagat tgccagttaa aacaagaggg aaacttagct cttctttctc     4320

aagtcgtggc caacaacaag aacctggaag atacccttca aggagtcagc agagcacacc     4380

caaaacaact gtttcttcta aaactggtag aagcctaaga aagataaact ctgctcctcc     4440

tacagaaaca aaatctttaa gaattgccag tcgttctact cgccacagtc atggcccact     4500

gcaagcagat gtatttgtgg aattgcttag tcctcgtaga aaacgcagag gcaggaaaag     4560

tgctaataat acaccagaaa atagtcccaa cttccctaac ttcagagtca ttgccacaaa     4620

gtcaagtgaa cagtcaagat ctgtaaatat tgcttcaaaa ctttctctcc aagagagtga     4680

atccaaaaga agatgcagaa aaagacaatc tccagagcca tcgcctgtga cactgggtcg     4740

aaggagttct ggccgacagg gaggagttca tgaattgtct gcttttgaac aacttgttgt     4800

agaattggta cgacatgatg acagctggcc ttttttgaaa cttgtttcta aaatccaggt     4860

cccagactac tatgacatca tcaaaaagcc cattgcctta aatataattc gtgaaaaagt     4920

gaataagtgt gaatataaat tagcatctga gtttattgat gacattgagt taatgttttc     4980

gaactgcttt gaatacaacc ctcgtaacac aagtgaagca aaagctggaa ctaggcttca     5040

agcatttttt catattcagg ctcaaaagct tggactccac gtcacaccca gtaatgtgga     5100

ccaagttagc acaccaccgg ctgcgaaaaa gtcacgaatc tgactttgtc cttctaaagg     5160

atatatttga agaaaaacaa attgttcatg aaaatggaac attaaatcat gctgtataaa     5220

gcaataacaa ttgattgacc acatgaaagt gtggcctgca ctatattctc aattttaata     5280

ttaagcactc aggagaatgt aggaaagata tcctttgcta cagttttgtt cagtatctaa     5340

taagtttgat agatgtattg gatacagtac tggtttacag aggtttttgt acatttttga     5400

gatcattcat gtgtccagag atcttggaaa atattttttc acccacgatt tattttgtta     5460

ttgatgattt ttttttaaag tggtggtatt aagggagagt tatctacatg gatgagtctt     5520

ccgctatagc acagtttaga aaaggtgttt atgtcttaat taattgtttg agtacattct     5580

ttcaacacta cacatgaatg aatccaatct tataaccttg aagtgctgta ccagtgctgg     5640

ctgcaggtat taagtccaag tttattaact agatatttat ttagtattga gagtaatttg     5700

tgaatttgtt ttgtatttat aaaatttata cctgaaaaat gttccttaat gttttaaacc     5760

ttttactgtg tttttattcc tctaacttcc ttaatgatca atcaaaaaaa gtaacaccct     5820

ccctttttcc tgacagttct ttcagcttta cagaactgta ttataagttt ctatgtataa     5880

ctttttaact gtacaaataa aataacattt tttcaaataa aaaaaaaaaa aaaaa          5935


<210>  1384
<211>  8588
<212>  DNA
<213>  homo sapiens

<400>  1384
gagtagctcc agcggccacg ctgaggcgag ggtgacacac catgctcacg gcccctggag       60

accgtcgtgc tggcgagccg tgctccgtag ctccccggtc cgcctcggca gcggtcagag      120

tcgcctacag gagttgagcc gcccgcgcca gaaggttttg gcgaagctct tggagaggcg      180

tcgagcacag tagggcggcg ggggtgcgtt gagcgctcgg gggtcaggca gtcggccggg      240

atcgccgctg gggagcgttt ccgaggcgag gaggaggagg aggagatgct gctcctcttc      300

tccccctccc caggctcctt ctacagctcc ttcagcccac gcccgcagcc gcttgtggga      360

gaagtggtgg tggctctcgg cgcccgcggc ggctgccggc ggcccgcccc gacgccgcgt      420

ccctgcagcc ctcgcccggc gctccagtag caggacccgg tctcgggacc agccggtaat      480

atgcacgtgt cactagctga ggccctggag gttcggggtg gaccacttca ggaggaagaa      540

atatgggctg tattaaatca aagtgctgaa agtctccaag aattattcag aaaagtaagc      600

ctagctgatc ctgctgccct tggcttcatc atttctccat ggtctctgct gttgctgcca      660

tctggtagtg tgtcatttac agatgaaaat atttccaatc aggatcttcg agcattcact      720

gcaccagagg ttcttcaaaa tcagtcacta acttctctct cagatgttga aaagatccac      780

atttattctc ttggaatgac actgtattgg ggggctgatt atgaagtgcc tcagagccaa      840

cctattaagc ttggagatca tctcaacagc atactgcttg gaatgtgtga ggatgttatt      900

tacgctcgag tttctgttcg gactgtgctg gatgcttgca gtgcccacat taggaatagc      960

aattgtgcac cctcattttc ctacgtgaaa cacttggtaa aactggttct gggaaatctt     1020

tctgggacag atcagctttc ctgtaacagt gaacaaaagc ctgatcgaag ccaggctatt     1080

cgagatcgat tgcgaggaaa aggattacca acaggaagaa gctctacttc tgatgtacta     1140

gacatacaaa agcctccact ctctcatcag acctttctta acaaagggct tagtaaatct     1200

atgggatttc tgtccatcaa agatacacaa gatgagaatt atttcaagga cattttatca     1260

gataattctg gacgtgaaga ttctgaaaat acattctccc cttaccagtt caaaactagt     1320

ggcccagaaa aaaaacccat ccctggcatt gatgtgcttt ctaagaagaa gatctgggct     1380

tcatccatgg acttgctttg tacagctgac agagacttct cttcaggaga gactgccaca     1440

tatcgtcgtt gtcaccctga ggcagtaaca gtgcggactt caactactcc tagaaaaaag     1500

gaggcaagat actcagatgg aagtatagcc ttggatatct ttggccctca gaaaatggat     1560

ccaatatatc acactcgaga attgcccacc tcctcagcaa tatcaagtgc tttggaccga     1620

atccgagaga gacaaaagaa acttcaggtt ctgagggaag ccatgaatgt agaagaacca     1680

gttcgaagat acaaaactta tcatggtgat gtctttagta cctccagtga aagtccatct     1740

attatttcct ctgaatcaga tttcagacaa gtgagaagaa gtgaagcctc aaagaggttt     1800

gaatccagca gtggtctccc aggggtagat gaaaccttaa gtcaaggcca gtcacagaga     1860

ccgagcagac aatatgaaac accctttgaa ggcaacttaa ttaatcaaga gatcatgcta     1920

aaacggcaag aggaagaact gatgcagcta caagccaaaa tggcccttag acagtctcgg     1980

ttgagcctat atccaggaga cacaatcaaa gcgtccatgc ttgacatcac cagggatccg     2040

ttaagagaaa ttgccctaga aacagccatg actcaaagaa aactgaggaa tttctttggc     2100

cctgagtttg tgaaaatgac aattgaacca tttatatctt tggatttgcc acggtctatt     2160

cttactaaga aagggaagaa tgaggataac cgaaggaaag taaacataat gcttctgaac     2220

gggcaaagac tggaactgac ctgtgatacc aaaactatat gtaaagatgt gtttgatatg     2280

gttgtggcac atattggctt agtagagcat catttgtttg ctttagctac cctcaaagat     2340

aatgaatatt tctttgttga tcctgactta aaattaacca aagtggcccc agagggatgg     2400

aaagaagaac caaagaaaaa gaccaaagcc actgttaatt ttactttgtt tttcagaatt     2460

aaatttttta tggatgatgt tagtctaata caacatactc tgacgtgtca tcagtattac     2520

cttcagcttc gaaaagatat tttggaggaa aggatgcact gtgatgatga gacttcctta     2580

ttgctggcat ccttggctct ccaggctgag tatggagatt atcaaccaga ggttcatggt     2640

gtgtcttact ttagaatgga gcactatttg cccgccagag tgatggagaa acttgattta     2700

tcctatatca aagaagagtt acccaaattg cataatacct atgtgggagc ttctgaaaaa     2760

gagacagagt tagaattttt aaaggtctgc caaagactga cagaatatgg agttcatttt     2820

caccgagtgc accctgagaa gaagtcacaa acaggaatat tgcttggagt ctgttctaaa     2880

ggtgtccttg tgtttgaagt tcacaatgga gtgcgcacat tggtccttcg ctttccatgg     2940

agggaaacca agaaaatatc tttttctaaa aagaaaatca cattgcaaaa tacatcagat     3000

ggaataaaac atggcttcca gacagacaac agtaagatat gccagtacct gctgcacctc     3060

tgctcttacc agcataagtt ccagctacag atgagagcaa gacagagcaa ccaagatgcc     3120

caagatattg agagagcttc gtttaggagc ctgaatctcc aagcagagtc tgttagagga     3180

tttaatatgg gacgagcaat cagcactggc agtctggcca gcagcaccct caacaaactt     3240

gctgttcgac ctttatcagt tcaagctgag attctgaaga ggctatcctg ctcagagctg     3300

tcgctttacc agccattgca aaacagttca aaagagaaga atgacaaagc ttcatgggag     3360

gaaaagccta gagagatgag taaatcatac catgatctca gtcaggcctc tctctatcca     3420

catcggaaaa atgtcattgt taacatggaa cccccaccac aaaccgttgc agagttggtg     3480

ggaaaacctt ctcaccagat gtcaagatct gatgcagaat ctttggcagg agtgacaaaa     3540

cttaataatt caaagtctgt tgcgagttta aatagaagtc ctgaaaggag gaaacatgaa     3600

tcagactcct catccattga agaccctggg caagcatatg ttctaggaat gactatgcat     3660

agttctggaa actcttcatc ccaagtaccc ttaaaagaaa atgatgtgct acacaaaaga     3720

tggagcatag tatcttcacc agaaagggag atcaccttag tgaacctgaa aaaagatgca     3780

aagtatggct tgggatttca aattattggt ggggagaaga tgggaagact ggacctaggc     3840

atatttatca gttcagttgc ccctggagga ccagctgact tggatggatg cttgaagcca     3900

ggagaccgtt tgatatctgt gaatagtgtg agtctggagg gagtcagcca ccatgctgca     3960

attgaaattt tgcaaaatgc acctgaagat gtgacacttg ttatctctca gccaaaagaa     4020

aagatatcca aagtgccttc tactcctgtg catctcacca atgagatgaa aaactacatg     4080

aagaaatctt cctacatgca agacagtgct atagattctt cttccaagga tcaccactgg     4140

tcacgtggta ccctgaggca catctcggag aactcctttg ggccatctgg gggcctgcgg     4200

gaaggaagcc tgagttctca agattccagg actgagagtg ccagcttgtc tcaaagccag     4260

gtcaatggtt tctttgccag ccatttaggt gaccaaacct ggcaggaatc acagcatggc     4320

agcccttccc catctgtaat atccaaagcc accgagaaag agactttcac tgatagtaac     4380

caaagcaaaa ctaaaaagcc aggcatttct gatgtaactg attactcaga ccgtggagat     4440

tcagacatgg atgaagccac ttactccagc agtcaggatc atcaaacacc aaaacaggaa     4500

tcttcctctt cagtgaatac atccaacaag atgaatttta aaactttttc ttcatcacct     4560

cctaagcctg gagatatctt tgaggttgaa ctggctaaaa atgataacag cttggggata     4620

agtgtcacgg tactgtttga caagggaggt gtgaatacga gtgtcagaca tggtggcatt     4680

tatgtgaaag ctgttattcc ccagggagca gcagagtctg atggtagaat tcacaaaggt     4740

gatcgcgtcc tagctgtcaa tggagttagt ctagaaggag ccacccataa gcaagctgtg     4800

gaaacactga gaaatacagg acaggtggtt catctgttat tagaaaaggg acaatctcca     4860

acatctaaag aacatgtccc ggtaacccca cagtgtaccc tttcagatca gaatgcccaa     4920

ggtcaaggcc cagaaaaagt gaagaaaaca actcaggtca aagactacag ctttgtcact     4980

gaagaaaata catttgaggt aaaattattt aaaaatagct caggtctagg attcagtttt     5040

tctcgagaag ataatcttat accggagcaa attaatgcca gcatagtaag ggttaaaaag     5100

ctctttcctg gacagccagc agcagaaagt ggaaaaattg atgtaggaga tgttatcttg     5160

aaagtgaatg gagcctcttt gaaaggacta tctcagcagg aagtcatatc tgctctcagg     5220

ggaactgctc cagaagtatt cttgcttctc tgcagacctc cacctggtgt gctaccggaa     5280

attgatactg cgcttttgac cccacttcag tctccagcac aagtacttcc aaacagcagt     5340

aaagactctt ctcagccatc atgtgtggag caaagcacca gctcagatga aaatgaaatg     5400

tcagacaaaa gcaaaaaaca gtgcaagtcc ccatccagaa gagacagtta cagtgacagc     5460

agtgggagtg gagaagatga cttagtgaca gctccagcaa acatatcaaa ttcgacctgg     5520

agttcagctt tgcatcagac tctaagcaac atggtatcac aggcacagag tcatcatgaa     5580

gcacccaaga gtcaagaaga taccatttgt accatgtttt actatcctca gaaaattccc     5640

aataaaccag agtttgagga cagtaatcct tcccctctac caccggatat ggctcctggg     5700

cagagttatc aaccccaatc agaatctgct tcctctagtt cgatggataa gtatcatata     5760

catcacattt ctgaaccaac tagacaagaa aactggacac ctttgaaaaa tgacttggaa     5820

aatcaccttg aagactttga actggaagta gaactcctca ttaccctaat taaatcagaa     5880

aaaggaagcc tgggttttac agtaaccaaa ggcaatcaga gaattggttg ttatgttcat     5940

gatgtcatac aggatccagc caaaagtgat ggaaggctaa aacctgggga ccggctcata     6000

aaggttaatg atacagatgt tactaatatg actcatacag atgcagttaa tctgctccgg     6060

gctgcatcca aaacagtcag attagttatt ggacgagttc tagaattacc cagaatacca     6120

atgttgcctc atttgctacc ggacataaca ctaacgtgca acaaagagga gttgggtttt     6180

tccttatgtg gaggtcatga cagcctttat caagtggtat atattagtga tattaatcca     6240

aggtccgtcg cagccattga gggtaatctc cagctattag atgtcatcca ttatgtgaac     6300

ggagtcagca cacaaggaat gaccttggag gaagttaaca gagcattaga catgtcactt     6360

ccttcattgg tattgaaagc aacaagaaat gatcttccag tggtccccag ctcaaagagg     6420

tctgctgttt cagctccaaa gtcaaccaaa ggcaatggtt cctacagtgt ggggtcttgc     6480

agccagcctg ccctcactcc taatgattca ttctccacgg ttgctgggga agaaataaat     6540

gaaatatcgt accccaaagg aaaatgttct acttatcaga taaagggatc accaaacttg     6600

actctgccca aagaatctta tatacaagaa gatgacattt atgatgattc ccaagaagct     6660

gaagttatcc agtctctgct ggatgttgtg gatgaggaag cccagaatct tttaaacgaa     6720

aataatgcag caggatactc ctgtggtcca ggtacattaa agatgaatgg gaagttatca     6780

gaagagagaa cagaagatac agactgcgat ggttcacctt tacctgagta ttttactgag     6840

gccaccaaaa tgaatggctg tgaagaatat tgtgaagaaa aagtaaaaag tgaaagctta     6900

attcagaagc cacaagaaaa gaagactgat gatgatgaaa taacatgggg aaatgatgag     6960

ttgccaatag agagaacaaa ccatgaagat tctgataaag atcattcctt tctgacaaac     7020

gatgagctcg ctgtactccc tgtcgtcaaa gtgcttccct ctggtaaata cacgggtgcc     7080

aacttaaaat cagtcattcg agtcctgcgg ggtttgctag atcaaggaat tccttctaag     7140

gagctggaga atcttcaaga attaaaacct ttggatcagt gtctaattgg gcaaactaag     7200

gaaaacagaa ggaagaacag atataaaaat atacttccct atgatgctac aagagtgcct     7260

cttggagatg aaggtggcta tatcaatgcc agcttcatta agataccagt tgggaaagaa     7320

gagttcgttt acattgcctg ccaaggacca ctgcctacaa ctgttggaga cttctggcag     7380

atgatttggg agcaaaaatc cacagtgata gccatgatga ctcaagaagt agaaggagaa     7440

aaaatcaaat gccagcgcta ttggcccaac atcctaggca aaacaacaat ggtcagcaac     7500

agacttcgac tggctcttgt gagaatgcag cagctgaagg gctttgtggt gagggcaatg     7560

acccttgaag atattcagac cagagaggtg cgccatattt ctcatctgaa tttcactgcc     7620

tggccagacc atgatacacc ttctcaacca gatgatctgc ttacttttat ctcctacatg     7680

agacacatcc acagatcagg cccaatcatt acgcactgca gtgctggcat tggacgttca     7740

gggaccctga tttgcataga tgtggttctg ggattaatca gtcaggatct tgattttgac     7800

atctctgatt tggtgcgctg catgagacta caaagacacg gaatggttca gacagaggat     7860

caatatattt tctgctatca agtcatcctt tatgtcctga cacgtcttca agcagaagaa     7920

gagcaaaaac agcagcctca gcttctgaag tgacatgaaa agagcctctg gatgcatttc     7980

catttctctc cttaacctcc agcagactcc tgctctctat ccaaaataaa gatcacagag     8040

cagcaagttc atacaacatg catgttctcc tctatcttag aggggtattc ttcttgaaaa     8100

taaaaaatat tgaaatgctg tatttttaca gctactttaa cctatgataa ttatttacaa     8160

aattttaaca ctaaccaaac aatgcagatc ttagggatga ttaaaggcag catttgatga     8220

tagcagacat tgttacaagg acatggtgag tctattttta atgcaccaat cttgtttata     8280

gcaaaaatgt tttccaatat tttaataaag tagttatttt ataggggata cttgaaacca     8340

gtatttaagc tttaaatgac agtaatattg gcatagaaaa aagtagcaaa tgtttactgt     8400

atcaatttct aatgtttact atatagaatt tcctgtaata tatttatata ctttttcatg     8460

aaaatggagt tatcagttat ctgtttgtta ctgcatcatc tgtttgtaat cattatctca     8520

ctttgtaaat aaaaacacac cttaaaacat gaacaagcca aaactgtgtg cagacaaaaa     8580

aaaaaaaa                                                              8588


<210>  1385
<211>  2380
<212>  DNA
<213>  homo sapiens

<400>  1385
atgttgtgct cttgcctggc ccgctgctgt cgccgccgcc gcgctcgtgg ggtccgtgtg       60

cctcgtcggc ccggcccgcg ggctttctcc cattggcgga aggcgacggc gggggggctc      120

gctcgtgatt ggtcggtggc ggggaggccg cggacctggc accttattgg acgcgccagc      180

tccggtctag gggacacggg cttccaccat gttagccagg ctggtcttca actcctgacc      240

tcaggtgatc cacccacctc ggcctcccaa agtgctggga ttataggcgt gagccaccgt      300

gcccagccag gctatgctgg gtgtcttttt gagatttagg aacctctcag aataaaatct      360

ggaagcctgt tccatttgca ttatgagatt tgcattacaa tgcaggctga agtgcagtag      420

tgcaatcatg gctcattgca gtctcccagc tcctcggctc aagtgatcct cctgccccag      480

cctcctgagt agcgggagct acagacacac aaacacagga tactgccaga aactgggcaa      540

gaggctgttt gtgaatctca gaaggcaccc ggatcttgct ctgctgttcc tgctcaggct      600

ggagtgcagt ggcgcaatca tggctcactg caggcttgac cacccaggct caagcagtcc      660

tcccgcctca gcctcttgtc gagatgtcca cagaaggagg atttggtggt actagcagca      720

gtgatgccca gcaaagccta cagtcgttct ggcctcgggt catggaagaa atccggaatt      780

taacagtgaa agacttccga gtgcaggaac tcccactggc tcgtattaag aagattatga      840

aactggatga agatgtgaag atgatcagtg cagaagcgcc tgtactcttt gccaaggcag      900

cccagatttt tatcacagag ttgactcttc gagcctggat tcacacagaa gataacaagc      960

gccggactct acagagaaat gatatcgcca tggcaattac aaaatttgat cagtttgatt     1020

ttctcatcga tattgttcca agagatgaac tgaaacctcc aaagcgtcag gaggaggtgc     1080

gccagtctgt aactcctgcc gagccagtcc agtactattt cacgctggct cagcaaccca     1140

ccgctgtcca agtccagggc cagcagcaag gccagcagac caccagctcc acgaccacca     1200

tccagcctgg gcagatcatc atcgcacagc ctcagcaggg ccagaccatg caggtgatgc     1260

agcagatcat cactaacaca ggagagatcc agcagatccc ggtgcagctg aatgccggcc     1320

agctgcagta tatccgctta gcccagcctg tatcaggcac tcaagttgtg cagggacaga     1380

tccagacact tgccaccaat gctcaacaga ttacacagac agaggtccag caaggacagc     1440

agcagttcag ccagttcaca gatggacagc agctctacca gatccagcaa gtcaccatgc     1500

ctgcgggcca ggacctcgcc cagcccatgt tcatccagtc agccaaccag ccctccgacg     1560

ggcaggcccc ccaggtgacc ggcgactgag ggcctgagct ggcaaggcca aggacaccca     1620

acacaatttt tgccatacag ccccaggcaa tgggcacagc cttcctcccc agaggacccg     1680

gccgacctca gcgcctcctg caggctagga cactggtgca ctacacccca tgcctggggg     1740

ccgagattct ccagcagaaa gatgcaatat tttttgtttc ctttttttcc atttttttct     1800

ctaaggaatc aatatttcaa tatgttgagt gtgtgtccaa tgctatgaaa ttaaaatatt     1860

aaataacata tttatggcat tttcttgaag agtgtggttg aagaaatatt tctccttttg     1920

tttttctttt ttttttgttt gttactgcca cttcttttta ggagcaaatc tccccagggg     1980

tgtacggtat ttcttgactc tgggaacagc tgctaccccc aagacttgcc acgttgttct     2040

gccctcagat ggaattaggt gaatgtgtgt agctgctttt tcactcgtgg tcctctcccc     2100

atcccttgct ctgaccccag agctctgtgt atttgcatcc agaggccatg gaaacattct     2160

ttgcatttaa gagacagatt tattccctgt ggagagtggg tggattcatt gccacactct     2220

tttctcccag ggacccagga aactaggact ttgtgtgttt gctgcccacc tcccttttat     2280

tttttaaatg cattaaaaac tgtgctagtc tcctttgcat ggacttcaag ctgcatgaaa     2340

tgcaataaat ctcattttag ataaaaaaaa aaaaaaaaaa                           2380


<210>  1386
<211>  4776
<212>  DNA
<213>  homo sapiens

<400>  1386
cggccgcatc cttgccgccc gccccggccc agccgcgtcc cggagccgtc gggcatggag       60

ccgtggaagc agtgcgcgca gtggctcatc cattgcaagg tgctgcccac caaccaccgg      120

gtgacctggg actcggctca ggtgttcgac cttgcgcaga ccctccgcga tggagtcctg      180

ctctgccagc tgcttaacaa cctccgggcg cactccatca acctgaagga gatcaacctg      240

aggccgcaga tgtcccagtt tctctgtttg aagaacataa ggacatttct cacggcctgt      300

tgtgagacgt ttggaatgag gaaaagtgaa cttttcgagg catttgactt gtttgatgtt      360

cgtgactttg gaaaggttat agaaacatta tcacgacttt ctcgaacacc tatagcattg      420

gccacaggaa tcaggccctt cccaacagaa gaaagcatta atgatgaaga catctacaaa      480

ggccttcctg atttaataga tgaaaccctt gtggaagatg aagaagatct ctatgactgt      540

gtttatgggg aagatgaagg tggagaagtc tatgaggact taatgaaggc agaggaagca      600

catcagccca aatgtccaga aaatgatata cgaagttgtt gtctagcaga aattaagcag      660

acagaagaaa aatatacaga aactttggag tcaatagaaa agtatttcat ggcaccacta      720

aaaagatttc tgacagcagc agaatttgat tcagtattca tcaacattcc tgaacttgta      780

aaacttcatc ggaacctaat gcaagagatt catgattcca ttgtaaataa aaatgaccag      840

aacttgtacc aagtttttat taactacaag gaaagattgg ttatttacgg gcagtactgc      900

agtggagtgg agtcagccat ctctagttta gactacattt ctaagacaaa agaagatgtc      960

aaactgaaat tagaggaatg ttccaaaaga gcaaataatg ggaaatttac tcttcgagac     1020

ttgcttgtgg ttcctatgca acgtgtttta aagtaccacc ttctcctcca ggaactggtc     1080

aaacatacca ctgatccgac tgagaaggca aatctgaaac tggctcttga tgccatgaag     1140

gacttggcac aatatgtgaa tgaagtgaaa agagataatg agacccttcg tgaaattaaa     1200

cagtttcagc tatctataga gaatttgaac caaccagttt tgctttttgg acgacctcag     1260

ggagatggtg aaattcgaat aaccactcta gacaagcata ccaaacaaga aaggcatatc     1320

ttcttatttg atttggcagt gatcgtatgt aagagaaaag gtgataacta tgaaatgaag     1380

gaaataatag atcttcagca gtacaagata gccaataatc ctacaaccga taaagaaaac     1440

aaaaagtggt cttatggctt ctacctcatc catacccaag gacaaaatgg gttagaattt     1500

tattgcaaaa caaaagattt aaagaagaaa tggctagaac agtttgaaat ggctttgtct     1560

aacataagac cagactatgc agactccaat ttccacgact tcaagatgca taccttcact     1620

cgagtcacat cctgcaaagt ctgccagatg ctcctgaggg gaacatttta tcaaggctat     1680

ttatgtttta agtgtggagc gagagcacac aaagaatgtt tgggaagagt agacaattgt     1740

ggcagagtta attctggtga acaagggaca ctcaaactac cagagaaacg gaccaatgga     1800

ctgcgaagaa ctcctaaaca ggtggatcca ggtttaccaa agatgcaggt cattaggaac     1860

tattctggaa caccaccccc agctctgcat gaaggacccc ctttacagct ccaggccggg     1920

gataccgttg aacttctgaa aggagatgca cacagtctgt tttggcaggg cagaaattta     1980

gcatctggag aggttggatt ttttccaagt gatgcagtca agccttgccc atgtgtgccc     2040

aaaccagtag attattcttg ccaaccctgg tatgctggag caatggaaag attgcaagca     2100

gagaccgaac ttattaatag ggtaaatagt acttaccttg tgaggcacag gaccaaagag     2160

tcaggagaat atgcaattag cattaagtac aataatgaag caaagcacat caagatttta     2220

acaagagatg gcttttttca cattgcagaa aatagaaaat ttaaaagttt aatggaactt     2280

gtggagtact acaagcatca ttctctcaag gaagggttca gaaccttaga tacaactctg     2340

cagtttccat acaaggagcc agaacattca gctggacaga ggggtaatag agcaggcaac     2400

agcttgttaa gtccaaaagt gctgggcatt gccatcgctc ggtatgactt ctgtgcaaga     2460

gatatgagag agttgtcctt gttgaaagga gatgtggtga agatttacac aaagatgagt     2520

gcaaatggct ggtggagagg agaagtaaat ggcagggtgg gctggtttcc atccacatat     2580

gtggaagagg atgaataaat tcaaatcccg tgttgcaccc tgcaccaaaa atttcagaga     2640

agggataaat agaagcctgc acagcatcgt gaattaactg aagtgtttaa aaagctgcat     2700

ttctggctgt tcaacatcct ccctccttag cccctcctaa gtcttaatgc tgagatttct     2760

aaagatgctg gtactgacag attaatggct tgcctagagc tgtgcaagaa acagcctgcc     2820

agtctgtcat tgtcagggac cagggcaaaa ccaagagctg ttcttcccag aagagccctg     2880

caaacacatt ggttcgtgct tccctttact tcttctggtc agataccatg aatgccagtc     2940

atcagtaaat cttaatacac ttttgcttta ttctcacatg ccattcacca gattatttga     3000

tggtacaaag aagcagaagt gtaattttcc ttttcccagc atgacgaaaa attggagttc     3060

tgccatttga gcagcttact ggaaagatcc agccttactt gtcttaaatt gtccaacaag     3120

gtgactcatt gcccggcaaa cacttttacc ctcagatgtt actcatgata ttataaaata     3180

tgaggccagt gctcaggttt gcatcataag tgagctatcc ctgaagggtt ttaattactt     3240

atttggtgtc ctgattatat ttgcaaactt ctttataaaa ggtgaaaaaa gcacacaaaa     3300

gagagggtgt cttcatatta aaccttcaca accttcatga tttcatagga ttattttgga     3360

aatatagcac ttgactttat gaaaggatct gggctaggta tattaagggt agttgccaat     3420

aacctgaaga agctggcatt gtttacagaa acagatcaag ggctataatt tatgtcattt     3480

tatagcagca gtatctatta atacatgcct tttcctccca tccacctccc ccgcacacac     3540

acaaagatga cctgggacat gattttttta ttcccacatt ttcttggagc acaaacaact     3600

ttgttgagga ttttggaagg aaagcacaac tgggtccttt attcatttct gggacagaaa     3660

gagggtcagt ggacttttgt gggcctccag cttctctcag agtctccccc tctgcagccc     3720

atcctgggag tgtattaact ggagggaaga tgggtcttgc agtacatttg ttttgcccag     3780

ccatcactct tttttgtgag gagcctaaat acattcttcc tggggtccag agtccccatt     3840

caaggcagtc aagttaagac actaacttgg ccctttcctg atggaaatat ttcctccata     3900

gcagaagttg tgttctgaca agactgagag agttacatgt tgggaaaaaa aagaagcatt     3960

aacttagtag aactgaacca ggagcattaa gttctgaaat tttgaatcat ctctgaaatg     4020

aagcaggtgt agcctgccct ctcatcaatc cgtctgggtg ccagaactca aggttcagtg     4080

gacacatccc cctgttagag accctcatgg gctaggactt ttcatctagg atagattcaa     4140

gacctttacc tcagaattat gtaaactgtg attgtgtttt agaaaaatta ttatttgcta     4200

aaaccattta agtctttgta tatgtgtaaa tgatcacaaa aatgtatttt ataaaatgtt     4260

ctgtacaata aagttacacc tcaaagtgta ctcttggaat ggattctttc ctgtaaagtc     4320

ttatctgcga ctctgtctcg ggaatgtttt gtctgttgcc gtcagccgaa ctttgttatg     4380

gagggagcag cctcacacaa gcagaaacac tcctgtggat ggtattgtag catgtattgt     4440

ttattttagt caatagaccc tctccttata aatggtgttt agtcttcctg ttgcatttca     4500

tgggcctggg ggtttcctag cagaggatat tggagcccct ttttgtgaca ttaccaatta     4560

catctttgtc cacgtttaat actttgtttt ggaaaattta aatgctgcag atttgtgtag     4620

agttctaata ccaaagacag aagtaaatgt tttccatata ctttgtcttg cctgtatgca     4680

gccctcgtgt aatacggtga attagagtgg tatttcactt tgtattattt tgtaaatatg     4740

tcaatataat aaatagtgac taaattgata aaaaaa                               4776


<210>  1387
<211>  4687
<212>  DNA
<213>  homo sapiens

<400>  1387
agcctcctcc actccctcct cctcctcctc ctcgcacggt aatgggaggc tcctaggcag       60

gagaagcaaa agaaggaatt gtttgcgagt tcagtcatcc aaaaagcttc ttccatatgg      120

agggaccggg tgcgctgggc gcggcgtccc ctgcgttgtc ctcctgctgc cgcccccgcg      180

gccgccgctt tctgccgcgg ggaccctgag ccccggcccg ccggtgtcag ccgccgcgcg      240

cgcgcacaga cacacacaca gagacacaca aacacacaca gaaaagacac acacgcgcac      300

acacggcgcg cacaccctca cgcccgccac agccacaaca cgcccgcacg cgccctccct      360

ctccggcccg caacttctcg gtcctcggct cctttgttgc tccagccgcg gccgctcgcc      420

cgtgttgtgt gtccccggtg tcaccgagcg tgttgtgtgt ccgtgcggcg cggcgctgtg      480

tggctccctc gcgcccacca cgctggcccc cgggccccgg ctcgcccttc ccaggcgccg      540

gctgcagcag agtttcagaa caagcttcct ggaacccatg acccatgaag tcttgtcgac      600

atttataccg tctgagggta gcagctcgaa agtagaagaa agtgttgcca gggacggcag      660

tatctctttg tgtgaccctg gcggcttatg ggacgttggc ttcagacctt tgtgatacac      720

catgctgcgt gggacgatga cggcgtggag aggaatgagg cctgaggtca cactggcttg      780

cctcctccta gccacagcag gctgctttgc tgacttgaac gaggtccctc aggtcaccgt      840

ccagcctgcg tccaccgtcc agaagcccgg aggcactgtg atcttgggct gcgtggtgga      900

acctccaagg atgaatgtaa cctggcgcct gaatggaaag gagctgaatg gctcggatga      960

tgctctgggt gtcctcatca cccacgggac cctcgtcatc actgccctta acaaccacac     1020

tgtgggacgg taccagtgtg tggcccggat gcctgcgggg gctgtggcca gcgtgccagc     1080

cactgtgaca ctagccaatc tccaggactt caagttagat gtgcagcacg tgattgaagt     1140

ggatgaggga aacacagcag tcattgcctg ccacctgcct gagagccacc ccaaagccca     1200

ggtccggtac agcgtcaaac aagagtggct ggaggcctcc agaggtaact acctgatcat     1260

gccctcaggg aacctccaga ttgtgaatgc cagccaggag gacgagggca tgtacaagtg     1320

tgcagcctac aacccagtga cccaggaagt gaaaacctcc ggctccagcg acaggctacg     1380

tgtgcgccgc tccaccgctg aggctgcccg catcatctac cccccagagg cccaaaccat     1440

catcgtcacc aaaggccaga gtctcattct ggagtgtgtg gccagtggaa tcccaccccc     1500

acgggtcacc tgggccaagg atgggtccag tgtcaccggc tacaacaaga cgcgcttcct     1560

gctgagcaac ctcctcatcg acaccaccag cgaggaggac tcaggcacct accgctgcat     1620

ggccgacaat ggggttgggc agcccggggc agcggtcatc ctctacaatg tccaggtgtt     1680

tgaaccccct gaggtcacca tggagctatc ccagctggtc atcccctggg gccagagtgc     1740

caagcttacc tgtgaggtgc gtgggaaccc cccgccctcc gtgctgtggc tgaggaatgc     1800

tgtgcccctc atctccagcc agcgcctccg gctctcccgc agggccctgc gcgtgctcag     1860

catggggcct gaggacgaag gcgtctacca gtgcatggcc gagaacgagg ttgggagcgc     1920

ccatgccgta gtccagctgc ggacctccag gccaagcata accccaaggc tatggcagga     1980

tgctgagctg gctactggca cacctcctgt atcaccctcc aaactcggca accctgagca     2040

gatgctgagg gggcaaccgg cgctccccag acccccaacg tcagtggggc ctgcttcccc     2100

gcagtgtcca ggagagaagg ggcagggggc tcccgccgag gctcccatca tcctcagctc     2160

gccccgcacc tccaagacag actcatatga actggtgtgg cggcctcggc atgagggcag     2220

tggccgggcg ccaatcctct actatgtggt gaaacaccgc aaggtcacaa attcctctga     2280

cgattggacc atctctggca ttccagccaa ccagcaccgc ctgaccctca ccagacttga     2340

ccccgggagc ttgtatgaag tggagatggc agcttacaac tgtgcgggag agggccagac     2400

agccatggtc accttccgaa ctggacggcg gcccaaaccc gagatcatgg ccagcaaaga     2460

gcagcagatc cagagagacg accctggagc cagtccccag agcagcagcc agccagacca     2520

cggccgcctc tcccccccag aagctcccga caggcccacc atctccacgg cctccgagac     2580

ctcagtgtac gtgacctgga ttccccgtgg gaatggtggg ttcccaatcc agtccttccg     2640

tgtggagtac aagaagctaa agaaagtggg agactggatt ctggccacca gcgccatccc     2700

cccatcgcgg ctgtccgtgg agatcacggg cctagagaaa ggcacctcct acaagtttcg     2760

agtccgggct ctgaacatgc tgggggagag cgagcccagc gccccctctc ggccctacgt     2820

ggtgtcgggc tacagcggtc gcgtgtacga gaggcccgtg gcaggtcctt atatcacctt     2880

cacggatgcg gtcaatgaga ccaccatcat gctcaagtgg atgtacatcc cagcaagtaa     2940

caacaacacc ccaatccatg gcttttatat ctattatcga cccacagaca gtgacaatga     3000

tagtgactac aagaaggata tggtggaagg ggacaagtac tggcactcca tcagccacct     3060

gcagccagag acctcctacg acattaagat gcagtgcttc aatgaaggag gggagagcga     3120

gttcagcaac gtgatgatct gtgagaccaa agctcggaag tcttctggcc agcctggtcg     3180

actgccaccc ccaactctgg ccccaccaca gccgcccctt cctgaaacca tagagcggcc     3240

ggtgggcact ggggccatgg tggctcgctc cagcgacctg ccctatctga ttgtcggggt     3300

cgtcctgggc tccatcgttc tcatcatcgt caccttcatc cccttctgct tgtggagggc     3360

ctggtctaag caaaaacata caacagacct gggttttcct cgaagtgccc ttccaccctc     3420

ctgcccgtat actatggtgc cattgggagg actcccaggc caccaggcca gtggacagcc     3480

ctacctcagt ggcatcagtg gacgggcctg tgctaatggg atccacatga ataggggctg     3540

cccctcggct gcagtgggct acccgggcat gaagccccag cagcactgcc caggcgagct     3600

tcagcagcag agtgacacca gcagcctgct gaggcagacc catcttggca atggatatga     3660

cccccaaagt caccagatca cgaggggtcc caagtctagc ccggacgagg gctctttctt     3720

atacacactg cccgacgact ccactcacca gctgctgcag ccccatcacg actgctgcca     3780

acgccaggag cagcctgctg ctgtgggcca gtcaggggtg aggagagccc ccgacagtcc     3840

tgtcctggaa gcagtgtggg accctccatt tcactcaggg cccccatgct gcttgggcct     3900

tgtgccagtt gaagaggtgg acagtcctga ctcctgccaa gtgagtggag gagactggtg     3960

tccccagcac cccgtagggg cctacgtagg acaggaacct ggaatgcagc tctccccggg     4020

gccactggtg cgtgtgtctt ttgaaacacc acctctcaca atttaggcag aagctgatat     4080

cccagaaaga ctatatattg tttttttttt aaaaaaaaaa agaagaaaaa agagacagag     4140

aaaattggta tttatttttc tattatagcc atatttatat atttatgcac ttgtaaataa     4200

atgtatatgt tttataattc tggagagaca taaggagtcc tacccgttga ggttggagag     4260

ggaaaataaa gaagctgcca cctaacagga gtcacccagg aaagcaccgc acaggctggc     4320

gcgggacaga ctcctaacct ggggcctctg cagtggcagg cgaggctgca ggaggcccac     4380

agataagctg gcaagaggaa ggatcccagg cacatggttc atcacgagca tgagggaaca     4440

gcaaggggca cggtatcaca gcctggagac acccacacag atggctggat ccggtgctac     4500

gggaaacatt ttcctaagat gcccatgaga acagaccaag atgtgtacag cactatgagc     4560

attaaaaaac cttccagaat caataatccg tggcaacata tctctgtaaa aacaaacact     4620

gtaacttcta aataaatgtt tagtcttccc tgtaaccttc aaactgaaaa aaaaaaaaaa     4680

aaaaaaa                                                               4687


<210>  1388
<211>  3785
<212>  DNA
<213>  homo sapiens

<400>  1388
gtaacgccgc gcaccctatc aggcggccac agggagcgcg cccgcggcct cgccctttct       60

cgcccctccc ttctcccctc tgggtccagc ctcagactga ggcttggaga caggagcatt      120

ccactcgcca cttcggcgcg cccccatgcc ctcttgtgcg cgtgcgcaga ggcggaccgc      180

aaggctaggg cgtgagggaa gggcgggcgt acgcccttgc gtgcgtctca ggcagcgcgc      240

acgccggcgt gagagggcac ggggaaaagg tggctctggc cggggtggct cggtttcctg      300

gggctatgta actgagctcg tcgacttagg ggtccttctt cgctgccctc gccgcgtgct      360

agcagggagt ttccgctcgg gagagagact gtcctcacgc ccgctgcgcc tcctcgacgg      420

cagagcaggc ttgctcgccc gtgggagcgt cccggccgag aagccctgag gggggagggg      480

aggccatttt gtcccgaccg actccccgga accgggcgga gcggctggga gaggctgcgg      540

agccgcggtc gccgccctcg gaggcactgg acgccgccac tgtcggggct tcctcaaagc      600

tgttcgtagg tcgcccgcgc cgtctcgagc ctttttccca cgcttccccg gtcctccggc      660

ctgagaacgc ccgagtgagg agttggccgt agtgagaggg accgatccct tggggccgcc      720

ggcggcgaga gcccgagccg ctcctcccaa tggcgaagaa gacgtacgac ctgcttttca      780

agctgctcct gatcggggat tccggagtgg ggaagacctg cgtccttttt cgtttttcgg      840

atgatgcctt caatactacc tttatttcca ccataggaat agacttcaag atcaaaacag      900

ttgaattaca aggaaagaag atcaagctac agatatggga tacagcaggc caggagcgat      960

ttcacaccat cacaacctcc tactacagag gcgcaatggg tatcatgcta gtatatgaca     1020

tcaccaatgg taaaagtttt gaaaacatca gcaaatggct tagaaacata gatgagcatg     1080

ccaatgaaga tgtggaaaga atgttactag gaaacaagtg tgatatggac gacaaaagag     1140

ttgtacctaa aggaaaagga gaacagattg caagggagca tggtattagg ttttttgaga     1200

ctagtgcaaa agcaaatata aacatcgaaa aggcgttcct cacgttagct gaagatatcc     1260

ttcgaaagac ccctgtaaaa gagcccaaca gtgaaaatgt agatatcagc agtggaggag     1320

gcgtgacagg ctggaagagc aaatgctgct gagcattctc ctgttccatc agttgccatc     1380

cactaccccg ttttctcttc ttgctgcaaa ataaaccact ctgtccattt ttaactctaa     1440

acagatattt ttgtttctca tcttaactat ccaagccacc tattttattt gttctttcat     1500

ctgtgactgc ttgctgactt tatcataatt ttcttcaaac aaaaaaatgt atagaaaaat     1560

catgtctgtg agttcatttt taaatgtact tgctcagctc aactgcattt cagttgtatt     1620

atagtccagt tcttatcaac attaaaacct atagcaatca tttcaaatct attctgcaaa     1680

ttgtataaga ataaagttag aattaacaat tttattttgt acaacagtgg aattttctgt     1740

catggataat gtgcttgagt ccctataatc tatagacatg tgatagcaaa agaaacaaac     1800

aaaagccagg aaaacactca ttttcgcctt gaatatgtaa atgggattaa ttttgtcctg     1860

tgccttatgt ggaaaggaac ttctttggtt ttcctttttt gttctggtgg aagcatgtgc     1920

aggagacata tcatccaaac ataaaccatt aaaatgtttg tggtttgctt ggctgtaatt     1980

ttcaaagtag ttaattgagg acaaagggta atgcagaagt gatagctttg gtttgctgag     2040

tcttgtttta agtggccttg atatttaaaa ctattcctgc caccatttct tctccttggc     2100

cacttcttcc ttgcgtctcc ctgcatgctg ctttatttgc ttctccctcc ccaaccacct     2160

catggtatat ttaagagtga aagggacaaa ctagtaggtt tgtcaagttt aatataaagc     2220

actgatgtaa cttgctaggt aaacggaaag ataagttcta actgcctact atccaatgtc     2280

agttaattgg tgtcttcccc cctcatttgc tctcttccct aaaatgtgtc ccagatgcct     2340

tcatttgctg ttttacttct atgttctgct tttcctcctc tctttgttcc cttcctgtct     2400

atccattgag tttatgaaat ggaagagtta actgcatgca ctagtgtttg gagggtgttg     2460

tggtttgtct ttctaattag gtgtatagcc tattcacttt cctagaataa atctcttaac     2520

ctaaatttga gtagtctgca ttttggcaac tcctctagca gcttggtagc ctagtacagg     2580

ttgttttttt aaaaaaggaa aagcaggaag gaggagtgaa ttttattaac atgtttgcca     2640

aatgtattga gatttggcct ctgaagaaca ctttttcagt gttaagtttc tttaccttaa     2700

gattcagaaa tactttagaa tattattaat tttaagtcct gtctttacat ccttttggaa     2760

aacttgtatt accatgggtt tggaaaaagg acaacgaaag gcttttcatg taaagataag     2820

atctttagct atctctaacc ctgtcctttt ttcactgcat tttttctagt tttgcttcat     2880

tgcttatcat taggataggg taagtgaagt ttgctatgct gctagcatcc taagatgata     2940

cctttgttga aagaattgtg aatagcatga ttcatttcta gcagaggctg agtttaggac     3000

agcagcttcc attgagaagt ctttctgtgt cgtgaatagc attttaatga cctcttggct     3060

cacataagca aacaacatag ggacgtatct gctatgaaaa tccacaaatt tttcagatag     3120

tgccctaaaa acaattttat atgcctcact ggttgttatt cttaggttat tcccacactt     3180

gactttatca ttgtttacta ctagtaaaaa gcagcattgc caaataatcc ctaattttcc     3240

actaaaaata taatgaaatg atgttaagct ttttgaaaag tttaggttaa acctactgtt     3300

gttagattaa tgtatttgtt gcttcccttt atctggaatg tggcattagc ttttttattt     3360

taaccctctt taattcttat tcaattccat gacttaaggt tggagagcta aacactggga     3420

tttttggata acagactgac agttttgcat aattataatc ggcattgtac atagaaagga     3480

tatggctacc ttttgttaaa tctgcacttt ctaaatatca aaaaagggaa atgaagtata     3540

aatcaatttt tgtataatct gtttgaaaca tgagttttat ttgcttaata ttagggcttt     3600

gccccttttc tgtaagtctc ttgggatcct gtgtagaagc tgttctcatt aaacaccaaa     3660

cagttaagtc cattctctgg tactagctac aaattcggtt tcatattcta cttaacaatt     3720

taaataaact gaaatatttc tagatggtct acttctgttc atataaaaac aaaacttgat     3780

ttcca                                                                 3785


<210>  1389
<211>  16142
<212>  DNA
<213>  homo sapiens

<400>  1389
gcccccgccg cccccgggcc ctgatggact gaatgaaggc tgcctacacc gcctatcgat       60

gcctcaccaa agacctagaa ggctgcgcca tgaacccgga gctgacaatg gaaagtctgg      120

gcactttgca cgggccggcc ggcggcggca gtggcggggg cggcggcggg ggcggcgggg      180

gcggcggcgg gggcccgggc catgagcagg agctgctggc cagccccagc ccccaccacg      240

cgggccgcgg cgccgctggc tcgctgcggg gccctccgcc gcctccaacc gcgcaccagg      300

agctgggcac ggcggcagcg gcggcagcgg cggcgtcgcg ctcggccatg gtcaccagca      360

tggcctcgat cctggacggc ggcgactacc ggcccgagct ctccatcccg ctgcaccacg      420

ccatgagcat gtcctgcgac tcgtctccgc ctggcatggg catgagcaac acctacacca      480

cgctgacacc gctccagccg ctgccaccca tctccaccgt gtctgacaag ttccaccacc      540

ctcacccgca ccaccatccg caccaccacc accaccacca ccaccagcgc ctgtccggca      600

acgtcagcgg cagcttcacc ctcatgcgcg acgagcgcgg gctcccggcc atgaacaacc      660

tctacagtcc ctacaaggag atgcccggca tgagccagag cctgtccccg ctggccgcca      720

cgccgctggg caacgggcta ggcggcctcc acaacgcgca gcagagtctg cccaactacg      780

gtccgccggg ccacgacaaa atgctcagcc ccaacttcga cgcgcaccac actgccatgc      840

tgacccgcgg tgagcaacac ctgtcccgcg gcctgggcac cccacctgcg gccatgatgt      900

cgcacctgaa cggcctgcac cacccgggcc acactcagtc tcacgggccg gtgctggcac      960

ccagtcgcga gcggccaccc tcgtcctcat cgggctcgca ggtggccacg tcgggccagc     1020

tggaagaaat caacaccaaa gaggtggccc agcgcatcac agcggagctg aagcgctaca     1080

gtatccccca ggcgatcttt gcgcagaggg tgctgtgccg gtctcagggg actctctccg     1140

acctgctccg gaatccaaaa ccgtggagta aactcaaatc tggcagggag accttccgca     1200

ggatgtggaa gtggcttcag gagcccgagt tccagcgcat gtccgcctta cgcctggcag     1260

cgtgcaaacg caaagagcaa gaaccaaaca aagacaggaa caattcccag aagaagtccc     1320

gcctggtgtt cactgacctc caacgccgaa cactcttcgc catcttcaag gagaacaaac     1380

gcccgtcaaa ggagatgcag atcaccattt cccagcagct gggcctggag ctcacaaccg     1440

tcagcaactt cttcatgaac gcccggcgcc gcagcctgga gaagtggcaa gacgatctga     1500

gcacaggggg ctcctcgtcc acctccagca cgtgtaccaa agcatgatgg aaggactctc     1560

acttgggcac aagtcacctc caaatgagga caacagatac caaaagaaaa caaaggaaaa     1620

agacaccgga ttcctagctg gggcccttca ctggtgattt gaaagcacaa ttctcttgca     1680

aagaaactta tattctagct gtaatcatag gccaggtgtt cttcttttgt ttttaatggc     1740

tatggagtcc aagtgcaagc tgaaaaatta atctcttaga accagacact gttctctgag     1800

catgctaagc atcccagaaa cccaaatggg gccttcctgg agcgagttaa ttccagtatg     1860

gtgtcaacca agctcgggat tgcttaaaat atcatccatc ccacttcagg tcctgtcagc     1920

ttcttgcagt cagagttcct atgagtaaca ataggagttt ggcctatgta aggactctga     1980

gtttaggctt ccaagataca acaataagag aagaatctag caacgagaat gacctcattt     2040

gctttccaca tgcttagcct cattatacca tgttatgtcc aagttcacag ccacaacatc     2100

agaatggtaa ttactgagca caagttttaa atatggacgt taaaaaaaaa aatccaagga     2160

cctgtttttc caacccagac atcttttcat tgaatgattt agaaagcttt aagttgatcc     2220

agcttacaat tttttttttc tttacctcct ggaaatctca tatggtcttg gatccgtcaa     2280

aaaaaccagt cagttcactt gcgctcaaag tatcaagcac aacaaagata aacagaagtg     2340

aggaaggttc tgggttcact acatctggat tttcaagaca cctattgtga agtcattagg     2400

gaattgatga gaatatggct tcaagcacat tttgcagttt gctacaaatt ctgttgtaca     2460

taatgcagac gcacactcag gaggccaatt taactgttaa cagtgcatgg agcgaatgca     2520

gcattttaaa agatctaggt ttttttaggt cattaatgtg tccttggttg atcagtcatc     2580

tggtccctcc tactgtgtgt tatgaccacc acgtaatcca ttctcgctct ttctgatttg     2640

gggtttttcc tcatccatcc cattagtagg gatgttttct gtgttttcta gcaagaaaaa     2700

aaaatcaatc aatcaaacct gcatacatgt tactcatgac tgtcatctag tcctaaatct     2760

cttctgttgt tgaatcatcc ttgcaaaaca gctgaataca tctggagaaa acacagcaca     2820

ccaaagaagc agaatactgc aaaccaaaga catttatgac ttgtcatttt ctagcctaaa     2880

aatactgtga ttacttttag aaatcagaaa acctctgcaa ctccgaatgg cattcagctc     2940

ttgcatttgg cgcatcatcg ggctgagcgg accagctaca ccaaggacat tagccaagcc     3000

acccagaggg gtggctttgc cacaccagtt gtcaccttcc catagcaagt ggaagagcgc     3060

ccacagaact ctgggagatt gcaaaggtca caatgtgcat atttaccagt gaatggcccc     3120

gggtggggcc acgtgggggt gttcaaagca agccaaacgc tgcaatcatt ctttacagac     3180

acttgagact gactttttta tgaattactt agtcgaaacc aaagaaactt tttctgcacc     3240

tacttctgca acaaacaaaa ctgtcccatt aaaatgaata aataaatccg taaatcaatg     3300

gaaatcacca ccaataagaa ggaagcacgc cagaaaataa acgaaaacaa aaacagggag     3360

acacactgtg ttcaaacaga cctcttggga cattttttgg aagcagattt taaagaaagg     3420

gttgagacaa agatagaaat aaggaagagc ctcagtggct gctgcttcat ttgacaactc     3480

acacggtaat cttaaagctg aagattgtct ttaatttgtg cctatgcagt ttttcaaaag     3540

aacacggaac agagcaacag aaacctcaac agctacaata ccaaagatga ggatttctca     3600

caccttttgt ttcagttcat tatctcctct tgcctggcta aaatactaat agcgccattg     3660

aactgtataa aggtaatcaa ttatgtttct ctgagcaaca aaaggaaagg gccatttatt     3720

tgattttatt gtttcatttc aattttgtct tatggttttt tgccccaaca tggaatctct     3780

caaaagtttc catggactcc aagtttaaga tgttgggata ttgaacagtt ctctctgctc     3840

agcagagggt agggaataac attatcactt gaatgttctt tgcttaaccc ttagacttgg     3900

ttccttctat gttcagagtc tcatcatcag gggaaggaaa gggagtgagg gtcagggata     3960

ggggtcttgg tgatgcatcc tctcccgagc cacagaacca aagagtttat agaggaattt     4020

acagcctcgt tttcatgtga ttgctacatc ctaacagggc ttcatttggg ggtgggggga     4080

aacatgtaaa aataattgcc agtttctact tttctattag ctttttaaaa atcagctgta     4140

aagttgcatt tctaaagaaa gatatatata atatataaaa tacatatata gatcaacttg     4200

acattggtga taaccaaaat tattgctgtc caaattcatg tcttgttttg gtccagtgct     4260

tcatttgcta agtattcggt tcagaatttt tctcatttct catgccattc cagagttaat     4320

ttgccactgt ggatgatttg aagtattcag atctctatgg aagtttctgg gacaggttta     4380

aagtcaagat caagcatttt agcatttaac ctgttgataa atggatccat ggtgtacatg     4440

agttttattt gtattcggag tcatctctat tctatccctc agcctcgatt aaggtggtga     4500

gtgaagtgca tccaacagac tcggcccaga actgggtcct gacagtgggg tgctcatctt     4560

ctgtaactgt tgggaaggct cggtggtcca ttttcaccag ttaaagaata tgaggccagc     4620

ccagaaatct gttctccagg agctgccctg tcccatctgg gtgtgccaga ccccctcagt     4680

gagcaggtcc accaaaggga cttctcacag gggaagccca actcctgttg caatgggttg     4740

atagatttcc tcagggtggt aattaccaat tcgtattttg acaagcctat gtgcaaccac     4800

agctggcact ggggtgggca gtggtgttgg gtgggatggg ggagagtgtc tcaatcctga     4860

agagaaaata taaagcaggt tttggggaga cttctggagt cctgccccta gagagcccca     4920

ttgttgttct ttgtgccccc tcctcattcc ccctatgtgg gtctccctat gcaggagctg     4980

tgagagaatg tgactctcca caatttttat aattcatcct tcctaggaga ttgttcattg     5040

gctcttccct tgtgtccctt tgtcccttgc tcatactcca tgtttccttt gtcaaaggac     5100

taagaaaaga gcatatttca gcagaggagt gttcccatgt gggttgattt caacttgggt     5160

atttctaaaa gagtccttgt gacatgtgtc cagtggaaat ggttgctctt ttccagactg     5220

gattgaggaa tggagcctgt ttgatttggt tagtgattct ttgacatact aatctcagcg     5280

tttgggtctc cagcatcctc tgaagatgtc tagactagta gaggctgcct ttgtgacctg     5340

acattacaac attggtcaaa ccagtcctct gataatcaga agaacatgtc ataattgttt     5400

aaaaaaaaaa aaaaggcaag aatttctctc caaggagctt taataaatgt ctcattccag     5460

ataatgtcat accagagaaa agtgcttgct tttagaaaat tatttacata catatataaa     5520

tatatatgtg tatctataca gttatgtatc aaaattttaa gccctgcaga atttcaattt     5580

gttagaaatc taacagaaaa aaatttctat attgaaaggt aatagaattt aacccagtga     5640

gtttactcaa ggatttttaa atttaagtta ataatttcag agaaaataac catttgggtg     5700

tggttatagt ttagtatcca ttacctcaat ccaaggaaaa ttccaggcat tcctcaacca     5760

tcaggaaaag gtacagtgtg aaggaacagt tctcagccaa atttcacatt cttgaggcaa     5820

cagaaatcaa aacactcaga gccattgagt ggaaaaacaa tttactttat tcctttacac     5880

aaataggctt gcattgtttt tgttttaatg tgattttggt actagggata taattatttc     5940

attccaggaa ataataaaaa aaaacagaca gagccaatac atttcttttt ttaaaggaaa     6000

cagcaacaac aataaaaact cagcaccaat atttaaaagc ttttccaaaa tgtaaaagaa     6060

gtgtttagct tgcaccatgc ataaaggtgc aggctagttg aaccaggaag catggcactt     6120

cctctggaga aatccagaaa gagttgcttc taagctccct tttccccctg caggctcttg     6180

gcaattgtag gctttagcaa atccagaata attttcaatt caagctaaaa taaaatcaac     6240

atttggaatg taaatctgat acacacacac ttttctaagt caaacaacat atttcaaaac     6300

caaaaataaa taccttttag ataatcagtt attttctttg tctatactgg gcacccacct     6360

actagtgcca gtaaattcaa gttgaacaga tttttaaaat cactattatc tgggtatggg     6420

ggaaacttcc ccacttttga aaatgttggt agaattatag gaatgtctgt ttgattatca     6480

ttaccaaagt gtcatgacag tatgcctttg tagtgaactc ggattttcag gagtttgaat     6540

agttggatat tttaaaatct aagaagaaaa ggcctgtttc caatgttgtt gaagaataat     6600

gaactctatt aaaaagtgga gaaaaagata atacatgtgg tcaaggttga ccacaaggcc     6660

caggcacaac taccttggcg ataatcttct agattcgtaa caggttagag ctgacttttt     6720

gtttttgttg ttgctgatgc tgtgtgattc agacttctca gcctaaccag gaagagtaag     6780

tggaaatggt agatgaagaa ggggtagagc tggtgtatct ataactttct gatatttgtc     6840

tgccaaactt gatatattag taattttttt atctttagct aagatcaagt cacccctgaa     6900

acaacaggag attctagttt taaaataagg ccacaaaaat ccttacggaa tgaagaatgg     6960

caccccagtt ggttgtataa gtctcataag ataatgatgt tgattttaaa tatggatgtc     7020

tcaatgcctg ttttctatca atgatttgtt tgtttccaag gtcggggagg gaaagagggg     7080

agggtttatc tgttttagaa agtctcagaa tacttataaa atacagaagt agttattaaa     7140

atatatagga cctcacatag gtagatacag aacttaccat tgaggctgat gggctgttgt     7200

gtgaatcaca caggacctta aatgaggctc attattctca cacaccaaaa tgactctgac     7260

agcctgaagc agttattgct agagcccaag ctttccttgg aggttttgga gttaggttga     7320

ttggaagtaa ccagctaata ccttttctag tggagaaaaa gacattgcta ccagcttgtt     7380

catcccatag aagtcttcca ctctgctcca tttttagcag caagcatttc atgtagcata     7440

aaccttggca gataagtgtg cctaaggttt atacagtctg tccgcttgga tgtatacaaa     7500

tttagataca tattttaaca tgtgttctca tagatgactt tataacaaca cacattacct     7560

ataggtgtct agactgtgta catacaagtg tgtacagaca agcttcatac gtatatactg     7620

taatccgtta caacaaataa attttaaatc atcgtttaac atgtatgtgg tacttctaca     7680

gtgtacattg ttttcattat ttattgtaac attgaaaacc acagtgcagg gaaaacaaaa     7740

gtatcccagc atcttcatcc tgtacacttg gaattaattt catttgggca tatccaagat     7800

aaactcaact ttcaagaaat cttgtatatt atttaatcat ctgtgttagg atgacaccta     7860

tgattgatga cttcggttga atagctttat tctggatttt tcataactaa agctaaatcc     7920

aaagacctga aaaaggacaa aaagaaaaaa aaaaaaagaa aaaacaaaga aaaagaagaa     7980

aaaataataa agtcaagcgc aaactgatgg ggagacagtg ggctctggtt tccaggattg     8040

agacaatggt actgcggtct tggggagact gcgttagcta gtggggagtg gtgatttttt     8100

tcatgcttgt cacatctaaa tggtctttaa catgagaaag ttttagaggt tataatttcc     8160

tgctttgttt ttatttagac tatcaaatga agttatacat gttgtcagtc aaaaaatgaa     8220

gacaccctct gccccacccc acagaatgct ttttatcttg tctctttggg ttatgaccca     8280

acaagctaag taccattaat gtaattaact tatttaaatt agttcctagt acataaatgt     8340

ataggatttg ggtaattatt taatcatcct tccttagttt gattctactc cttgtactta     8400

tttatcaaaa cctagaccaa tggtgcatca gagatgcaaa attctacttg gaatactctt     8460

gaagtttagt ttgctttata aagcagtgaa attctgttac agacagggaa gaaatacagg     8520

ttacaaaaag agaatttggg atattcttcc ctcttaaatt aacttttaaa atagtctaag     8580

taacaatttt taaattattt aacttaagtt cgcagcccca cctggtacca ggcgaacttc     8640

acctcttaat tattgtggcc ctcggagcct tcatattgta acttatttat ttaacttatt     8700

cagcatctgt gaaaggtgca ctgtatagtt tatattttta atttaaaaca acagagagca     8760

ctgcagtttg tttgctgtca gaacaacaga gcaaattttg tggacaagca atgactattc     8820

agcctgaacc tgtgcattca gaaaacataa gctgagaccc tgcttcacca gcctggattt     8880

cggggcttct atacagaaac tggaaaaata aattttaaaa aaatcgtaaa caaaaagaga     8940

gaaaccctta cactagctgc ttccaagaat gaactctgtg tgtatgtaaa gcaacaaaac     9000

aaaaaaggaa aaaaacaaaa agcagaaaaa agaaaaaaaa aatgaaaaac tttctatttc     9060

tagtgagaac caaagaaggc tacctcactg actttttcca tttgtaattt taatcgtgtt     9120

gatgacacca aagataccaa agatttcttt ctctgtgcgg tctgcatttt gcttgtgctc     9180

ttttataatt tgaacgattt tctctgacat atggtatgta cagccacagc tcagataccc     9240

caaagaaata attatctatg cgacggcggc tgctaatttg gaaagggata ttttctgtgt     9300

ttctcttata tgtttgctgt ctgctcgaca tgttcaagat gcgagttcag atgctgctgt     9360

aattggattc cttaaattct gattacaaat tgaggaagga aactggttgg aaatggcctt     9420

cagtcctagc catggcctct atccccgctg ggacctgtca cagtaaagac tgccaattac     9480

tgaaccacag aagctctgac cattgagtag ttgagctgga agagacctta ggaatcattt     9540

agtccaagcc ccggtggccc agaggaatga aatagttatc caaatcaaat aactcttgag     9600

agtgaaagcc cacacatgcc tcctggttcc tgccccagtg ctccgcttat tgtacagtgc     9660

tacctctgca tgagagcggt cccacattga caaataggat ggtggcaatc ctttagcaat     9720

gagcagggac tggggtttat ctcttaacat tttcagctgt aaaattagtc acaagcattt     9780

tcagtgtccc attagtacat agtcacatat ggtcggttgc ttcgtgaagg tggcctgtct     9840

tgaaatacta gggctcatac gggatttttg ccctaggaaa aacatgttga tcccaatgat     9900

gtgatcactt ttgaaccttt ccattacaaa gcattgtata gataactttt taattcagta     9960

ggaggagaaa gttcattctt ggcctgttgg ctttgattat tatgggtact ttaaagtcag    10020

tatttatcaa gaaagggaac ttgaccacca ttggcacatg tgacatttaa gctcttcagc    10080

cttttccttt ttagttgtag gtgtttacat ttcatttcta agccaactct gtatttatga    10140

gagaagttta agccttacat catttgatac taaagggtta tttgtggtaa atgaaaaatg    10200

accccaaaat tacagaggaa tatgccagtt taagaaatgg ctacttaaag ttgcttctct    10260

ctttccttct tactcatgaa attaattggt cttcttcaag tttctttaga ttccattaaa    10320

tgattaaatc actattaaga gccattcatc aacgtgattt gtgtgttagc caatgaatct    10380

gtctcagctt ttgaccaaat gggttttaga caaatgcaaa gatctgcctc tagtccatat    10440

ggctcttttt gagtgctagt attttgcatt tcacataatg tagttatttt gagcttttaa    10500

agagagcatt tagacaaaga agcaaagaga ggaagggacc aatcaactca tcagttccat    10560

gcatcaacaa agcatagcta gtagaggaat ataaatgaca gattgacaaa ctgtaggaaa    10620

cactgttact ctctttctga agttttcaag caccatccta tgtgaaagtt ccctcctgtc    10680

caaacaagct caaggcccat cttctcccta tacaaggcaa acctgtaagg ccttccttcc    10740

aaagagtaca ttgctttggt tttcttccta aattcctatt ggaattagaa ctctcagaat    10800

ccctgggaga cagagcaaag atgacttaat tcattgagca gcagagctcc ctataagtga    10860

acatcacctt ccccatcttt cctactgcca cacccatacg agagaggatc tagaaagagc    10920

gatggcagcc tgaacacaga aaacatcccc acttggcaga cctctcctca gcaatccccc    10980

cagcctcatg cttcacttgc aaagtgtgac ataaccacgg gacgagtgcc ttgcttgaac    11040

caaagcaacg atttagccag tctggacctc tctgtgcttt ttttaattct tcctgtgaat    11100

acctcagctt caactgggcc tccatacagt cagttggtgg gcttattgta ctgtggtgct    11160

ttgcaatgca accctgcaaa gaacaagatt tgtactaata ccaaaggttc tttctctatg    11220

tctcctcctc tgcctccctc gttcttccct tttttctagt tcttcacggt tccaaagctt    11280

tactatgaac ctgggcatgt tggcaatgca gaccgcgcaa ttccttaccg aattttctca    11340

gatatacctc atagacaata gtgtttagag taatgttatt atagcgtatg taataaatta    11400

ttcactgttt cttttggtaa ctgtgattta aaaaaagaaa aaagaaaaaa aagctttata    11460

cgttttaggt tgtgcttttg taatagatga aaaaaggtgc gcttaaaaag aaaatgtatg    11520

tttttttccc cctttggatt ttatttatgc tggattgggg aaagttgcag aatgagccca    11580

aagtttacag tttcatattt tgctgaagaa acaatctgtg ttcatttgct ctgttgaaaa    11640

gaataattat tttctacatt tgtgccactt ggtctgaaca attaattgtt ccgtgttaac    11700

agtgtagtat tatgattagc aactgccaat cagtgctata attttatgca tgaggctaaa    11760

aatttagcag tgtgatgcat tgtggtctta atagcaacat ttttcatttt gaactagatc    11820

ttcccctttg gttcaatgga ctttatttat gcatgggcgc ctattgtttg ttagcagttg    11880

tggaacagtt gtgtatacat taaactgtga aaatgtacac agttcagcct cagacggtgg    11940

taatattggt tttattggga gatgtgtcac ctcgaaaata ccctttacat ctgttgggat    12000

ctgaaaatga gtcacattga attgggttcc agctttataa tgagaaacgt tattcctaat    12060

ttttgagtta gccaatttgc attccacaaa ttgggatcct cataacccaa atatatcacc    12120

gtatgtgaga gggatttgaa agcgagtatt gaaaaactca cctttgcata tttaatttcc    12180

accaaaagga gttattttgg ctttatgctc atgaacttag acctaactgg ccatgtatat    12240

gtagatgcaa attcatctag ctgtggccct ctttgatctc tgcttgggaa tggctatttt    12300

tgactatgcg tggtttcttc tcgtattttg tgatcaggtc agctcccagt agaaactcaa    12360

atggcatcaa tattactaac tcttctctgc ccacttctct tttgtccact ctcctagaca    12420

ttcccaccaa ctgttccagt gatttgggca aaaatacgca gccatttccc aaaacttcac    12480

atgtgcagct atcatggctg tccctcccta gacttggagg tgactctcac ttaattttta    12540

cctgcccaac aatgttccat ctaccatcta aaaggtaata taagaagaag ttttgaaacc    12600

cactttagga aaaccatctt ctttaaatcc ttcaattatc tgaggcctct atatgtcaaa    12660

actatttttc agttgcaggg gattgggcaa acttgttctt tcttatactt gggttcaaag    12720

acccattctc cagtttcata tttcccaaac caaaatgctt gacataaagc caaatcaact    12780

gccaagcaca ctttattttg cataggagta tgcagcctag ggaaccttgg ttgaaaagca    12840

gcagtctgct atgcaaaata ttggaaatca ctgacagtgt agcattcata ttatctgtca    12900

atgagggtat attgggaacg tgctctcgtg aataataaaa agcaacatat ttttatttgg    12960

ccttataaat taggttgtgg taatgtaaac tttgatatat agtcttttta tttttctctt    13020

attaatctgc caaagatggg aacagataca agaatttttc aaattggctt ttgtaagaca    13080

attgatgatt gtaatagtgt ttaatcttcc agaaagcttt atatgttgtt ccacaataaa    13140

attgatattt gtttcagcaa agttttcctg acactcacaa acccacaaac tgttcctctt    13200

aatgcagata ttgtagaatc tacaaagttc aaatccattt ttgatccaaa gaaagtagag    13260

gagtatttga gacatgagtg tacccagccc tttttttaat cacaggcaat gcatgggtct    13320

ggctggttac actttgccaa gaagacttgt cttatgaaac ccaaggtata ttttgttatg    13380

ccattttatg tccttttctt ttaacattgt ggaaagtggt atgttgaatc aagtgtaagc    13440

tgagttttcc agacaactga agtagctaca tcatgaatgt tattttgtta ttaaagggtt    13500

tttactcagt gctttgtgcc aatggatgtc cttttccttg gagacacata actacaaaat    13560

tacctcagct tggcctggtt ttctctcctg ccctcttggg gaaacatggg cctggcctgg    13620

gaaaaggcag gtcatgggct ggaaggtagg ttttggtact aggaagaaat ctctgtatct    13680

gtcagcttta aagagaactg ggccaaaaat ctctaacctc actctctctg gactccaaca    13740

cttccctgca atcctttggt cttgagcatg tgccagcatg aaggcagact ccagttcata    13800

catgaaaggc aagaaaaaga aaatagtaac cttgaatctt ctgtgggcca ccaggcactc    13860

acctttcccc accttgcaca ctatccagtc aaggctattg cagcccatct ggtggcttta    13920

catgggacat taccaaaggc ttcttcctcc atcctggggt tgcaaaggat ccaggtcccc    13980

tccatccagt ggggctcttc cacatcagaa gtccccctcc caccatcctc tgcatcctgt    14040

ttagctatcc catctatacc ttttggagat gattatttag aaaacaaaga aaggtatgga    14100

atggggtttc ctattgtttg ctaggttata ttttagcaat tctcaattct ttgatctgga    14160

aaaatacaag agggaaaagg agaccccact atctccctgt gctttgctcc catctcaggg    14220

ggcaggggca gtgcacattg cctatgctgt tgatctgtct tgggcgacag gctgaatcac    14280

agctattgcc ccagccaaaa acatggccca tcaatgccta ctttatctct gcttgaaaat    14340

cctattcaaa aagttgtaga gtttgaggtt tttatccccc catatccttt gctttggtcc    14400

agtttggcct ttagcataag agtcagcttt atctctagga aagttttttc agattatgac    14460

aaggaacctg ccacctggga agaaaagagt ccgaagacta gcaatcggat aggtagtcat    14520

accattaaca gatacttcct tgaaggtaga atattatttc ctttctttac agttttgtgt    14580

tacacaagtc caagtggtgc cagcaaactt cttaccgtga aatgttgtaa aacacctggc    14640

atactgaaat ttctgaaaca aaaacacaag ctccacattg ataacttgat aaataaccac    14700

taaagtttag atgcagggac tgagatgata caggcaaaat cttggtgttg gtttctcttt    14760

taattcgtat cttcgatcac ctaacctttc tcaatccaag agcagttcag tcttttctcc    14820

ccaagtctag gatgccaaag agcatcatag gaaaagataa ttagggattg accagcattt    14880

caattagttc tcttcttcat ctttgcattt ctcaaaagtg ttctcctgga ccagagggaa    14940

agagctggtc catttttttt cattctttct attcaaattt ttccacccag acaatacttt    15000

attaacacag atactgtaga tccttccttg gtcagtgaat tattacaaga ggagctatcc    15060

ttccaccaaa gtgagtgaaa acaagttcca gtatcttttc ttccatccag ttttgttctc    15120

agaatccaag tcagtcctgg gtcttttctc actttagacc ctggcctcag atgtgtttat    15180

tcttgctatt taaaaatacc tttaaatttc acatgctggc ctgcagaact tgcatccttt    15240

gttctatact gttgactgct tgatggtatt gaaaggtgac tataatgagg gaagaaagga    15300

ggaggtaaag agagaagaat ttgtcccaga tctgtttaaa gtttcaaaat ttaaaaaggg    15360

acccattaaa ttatgggaaa atggctatag agtgtgagcc tccgttgacc atatgctcaa    15420

agaccgtact ctgccacctg ccttccaggt agctattcta gaaactcagt cctttgtgga    15480

aacccaacta ccttttaaaa gtctctttcc agattccaaa aggacaagag atcagagagt    15540

cacatatacg cctcttgttt tattttcttg ctttcacggg tattattgcc aagaaaatcg    15600

tagggaaaaa ctttaaactt ttcttttcag ttgatccctt tgacatcacc tctcatgttt    15660

aaaatcagga aaacacaccc ctaaaatttg cactctcttc cgttttgaaa aagaaaaccc    15720

acacacaaat gcacactatt accgtctttc accctgcgct atatttccaa agtgtattat    15780

aatccagata ttgccccatc tcaaacatgt taagtcagac tgtgctgaaa gactttccag    15840

ggacggtcaa cagggtatat gttcagtggc tgccctgaaa tcctggtggg gatgaggatc    15900

acgcttcatc atcaagggga tgcccatccc ctgataagct cccagtcctt ttggaagatt    15960

tctttgaatg ttaattgcat tttcagtttt gctcatttcc caccccaatg ttttgtctgc    16020

aacatcgctt acactggatt ctttctattt ttattcctat cattaaatgg tagtgctgta    16080

aattctgcaa ttaatgttaa ataaactgct ttaattcatt gaaaaaaaaa aaaaaaaaaa    16140

aa                                                                   16142


<210>  1390
<211>  2417
<212>  DNA
<213>  homo sapiens

<400>  1390
gcagcagaga ggagttgagg gcgatgagag cgggtactgc gaactgccgg gcgatgctgt       60

cgctgccgcc gtgatacgga gagcaacagt tccccagcaa cacccctccc cgacacaggc      120

acacaccccc cgacaggcac gcacacccac cccacagtgc ccggctcggc tgcgcctcct      180

ctattggccc aggaagccca cccagccccg ccacgcagag cccagaagga aagaaagcct      240

catgcctgag ccgaggggag caccatggat ctgacaaaaa tgggcatgat ccagctgcag      300

aaccctagcc accccacggg gctactgtgc aaggccaacc agatgcggct ggccgggact      360

ttgtgcgatg tggtcatcat ggtggacagc caggagttcc acgcccaccg gacggtgctg      420

gcctgcacca gcaagatgtt tgagatcctc ttccaccgca atagtcaaca ctatactttg      480

gacttcctct cgccaaagac cttccagcag attctggagt atgcatatac agccacgctg      540

caagccaagg cggaggacct ggatgacctg ctgtatgcgg ccgagatcct ggagatcgag      600

tacctggagg aacagtgcct gaagatgctg gagaccatcc aggcctcaga cgacaatgac      660

acggaggcca ccatggccga tggcggggcc gaggaagaag aggaccgcaa ggctcggtac      720

ctcaagaaca tcttcatctc gaagcattcc agcgaggaga gtgggtatgc cagtgtggct      780

ggacagagcc tccctgggcc catggtggac cagagccctt cagtctccac ttcatttggt      840

ctttcagcca tgagtcccac caaggctgca gtggacagtt tgatgaccat aggacagtct      900

ctcctgcagg gaactcttca gccacctgca gggcccgagg agccaactct ggctgggggt      960

gggcggcacc ctggggtggc tgaggtgaag acggagatga tgcaggtgga tgaggtgccc     1020

agccaggaca gccctggggc agccgagtcc agcatctcag gagggatggg ggacaaggtt     1080

gaggaaagag gcaaagaggg gcctgggacc ccgactcgaa gcagcgtcat caccagtgct     1140

agggagctac actatgggcg agaggagagt gccgagcagg tgccaccccc agctgaggct     1200

ggccaggccc ccactggccg acctgagcac ccagcacccc cgcctgagaa gcatctgggc     1260

atctactccg tgttgcccaa ccacaaggct gacgctgtat tgagcatgcc gtcttccgtg     1320

acctctggcc tccacgtgca gcctgccctg gctgtctcca tggacttcag cacctatggg     1380

gggctgctgc cccagggctt catccagagg gagctgttca gcaagctggg ggagctggct     1440

gtgggcatga agtcagagag ccggaccatc ggagagcagt gcagcgtgtg tggggtcgag     1500

cttcctgata acgaggctgt ggagcagcac aggaagctgc acagtgggat gaagacgtac     1560

gggtgcgagc tctgcgggaa gcggttcctg gatagtttgc ggctgagaat gcacttactg     1620

gctcattcag cgggtgccaa agcctttgtc tgtgatcagt gcggtgcaca gttttcgaag     1680

gaggatgccc tggagacaca caggcagacc catactggca ctgacatggc cgtcttctgt     1740

ctgctgtgtg ggaagcgctt ccaggcgcag agcgcactgc agcagcacat ggaggtccac     1800

gcgggcgtgc gcagctacat ctgcagtgag tgcaaccgca ccttccccag ccacacggct     1860

ctcaaacgcc acctgcgctc acatacaggc gaccacccct acgagtgtga gttctgtggc     1920

agctgcttcc gggatgagag cacactcaag agccacaaac gcatccacac gggtgagaaa     1980

ccctacgagt gcaatggctg tggcaagaag ttcagcctca agcatcagct ggagacgcac     2040

tatagggtgc acacaggtga gaagcccttt gagtgtaagc tctgccacca gcgctcccgg     2100

gactactcgg ccatgatcaa gcacctgaga acgcacaacg gcgcctcgcc ctaccagtgc     2160

accatctgca cagagtactg ccccagcctc tcctccatgc agaagcacat gaagggccac     2220

aagcccgagg agatcccgcc cgactggagg atagagaaga cgtacctcta cctgtgctat     2280

gtgtgaaggg aggcccgcgg cggtggagcc gagcggggag ccaggaaaga agagttggag     2340

tgagatgaag gaaggactat gacaaataaa aaaggaaaag aaaaaaaaaa acagaaggaa     2400

aaggaaaaaa aaaaaaa                                                    2417


<210>  1391
<211>  5214
<212>  DNA
<213>  homo sapiens

<400>  1391
agtctttgtg cagtcagggc ttctgctggg cagggccggc tgttaatctc gcctggcgga       60

gcggacaccg gggcgtggtg ggggagatgg gccttatagg tggcgtccgc tggtgagaaa      120

caccttgcgc aggtaaaagg gtggcggcga gagggagttc ccacccgtgg ctttcttaga      180

gaaatgaagt cttaagtctt aaatagacaa caaggagggg ccgatcggtg tcttttggac      240

gcgtctggag cccctccctc cgccaaagga aaagcccctt ggatgagagg caggcgcttc      300

agagaagcta agaaaagcac ctctccgcgc gccccacctc ctccgcctcg cgctcctcct      360

gagcagcggg cccagactgc gctccggccg cggccctcgc cccgcggagc cctcctaccc      420

cggcccgacg ctcggcccgc gacctgcccc gagccctctc catggaggca gcccgcccct      480

ccggctcctg gaacggagcc ctctgccggc tgctcctgct gaccctcgcg atcttaatat      540

ttgccagtga tgcctgcaaa aatgtgacat tacatgttcc ctccaaacta gatgccgaga      600

aacttgttgg tagagttaac ctgaaagagt gctttacagc tgcaaatcta attcattcaa      660

gtgatcctga cttccaaatt ttggaggatg gttcagtcta tacaacaaat actattctat      720

tgtcctcgga gaagagaagt tttaccatat tactttccaa cactgagaac caagaaaaga      780

agaaaatatt tgtctttttg gagcatcaaa caaaggtcct aaagaaaaga catactaaag      840

aaaaagttct aaggcgcgcc aagagaagat gggctccaat tccttgttcg atgctagaaa      900

actccttggg tccttttcca cttttccttc aacaggttca atctgacacg gcccaaaact      960

ataccatata ctattccata agaggtcctg gagttgacca agaacctcgg aatttatttt     1020

atgtggagag agacactgga aacttgtatt gtactcgtcc tgtagatcgt gagcagtatg     1080

aatcttttga gataattgcc tttgcaacaa ctccagatgg gtatactcca gaacttccac     1140

tgcccctaat aatcaaaata gaggatgaaa atgataacta cccaattttt acagaagaaa     1200

cttatacttt tacaattttt gaaaattgca gagtgggcac tactgtggga caagtgtgtg     1260

ctactgacaa agatgagcct gacacgatgc acacacgcct gaagtactcc atcattgggc     1320

aggtgccacc atcacccacc ctattttcta tgcatccaac tacaggcgtg atcaccacaa     1380

catcatctca gctagacaga gagttaattg acaagtacca gttgaaaata aaagtacaag     1440

acatggatgg tcagtatttt ggtctacaga caacttcaac ttgtatcatt aacattgatg     1500

atgtaaatga ccacttgcca acatttactc gtacttctta tgtgacatca gtggaagaaa     1560

atacagttga tgtggaaatc ttacgagtta ctgttgagga taaggactta gtgaatactg     1620

ctaactggag agctaattat accattttaa agggcaatga aaatggcaat tttaaaattg     1680

taacagatgc caaaaccaat gaaggagttc tttgtgtagt taagcctttg aattatgaag     1740

aaaagcaaca gatgatcttg caaattggtg tagttaatga agctccattt tccagagagg     1800

ctagtccaag atcagccatg agcacagcaa cagttactgt taatgtagaa gatcaggatg     1860

agggccctga gtgtaaccct ccaatacaga ctgttcgcat gaaagaaaat gcagaagtgg     1920

gaacaacaag caatggatat aaagcatatg acccagaaac aagaagtagc agtggcataa     1980

ggtataagaa attaactgat ccaacagggt gggtcaccat tgatgaaaat acaggatcaa     2040

tcaaagtttt cagaagcctg gatagagagg cagagaccat caaaaatggc atatataata     2100

ttacagtcct tgcatcagac caaggaggga gaacatgtac ggggacactg ggcattatac     2160

ttcaagacgt gaatgataac agcccattca tacctaaaaa gacagtgatc atctgcaaac     2220

ccaccatgtc atctgcggag attgttgcgg ttgatcctga tgagcctatc catggcccac     2280

cctttgactt tagtctggag agttctactt cagaagtaca gagaatgtgg agactgaaag     2340

caattaatga tacagcagca cgtctttcct atcagaatga tcctccattt ggctcatatg     2400

tagtacctat aacagtgaga gatagacttg gcatgtctag tgtcacttca ttggatgtta     2460

cactgtgtga ctgcattacc gaaaatgact gcacacatcg tgtagatcca aggattggcg     2520

gtggaggagt acaacttgga aagtgggcca tccttgcaat attgttgggc atagcattgc     2580

tcttttgcat cctgtttacg ctggtctgtg gggcttctgg gacgtctaaa caaccaaaag     2640

taattcctga tgatttagcc cagcagaacc taattgtatc aaacacagaa gctcctggag     2700

atgacaaagt gtattctgcg aatggcttca caacccaaac tgtgggcgct tctgctcagg     2760

gagtttgtgg caccgtggga tcaggaatca aaaacggagg tcaggagacc atcgaaatgg     2820

tgaaaggagg acaccagacc tcggaatcct gccggggggc tggccaccat cacaccctgg     2880

actcctgcag gggaggacac acggaggtgg acaactgcag atacacttac tcggagtggc     2940

acagttttac tcagccccgt cttggtgaaa aagtgtatct gtgtaatcaa gatgaaaatc     3000

acaagcatgc ccaagactat gtcctgacat ataactatga aggaagagga tcggtggctg     3060

ggtctgtagg ttgttgcagt gaacgacaag aagaagatgg gcttgaattt ttggataatt     3120

tggagcccaa atttaggaca ctagcagaag catgcatgaa gagatgagtg tgttctaata     3180

agtctctgaa agccagtggc tttatgactt ttaaaaaaaa ttacaaacca agaatttttt     3240

aaagcagaag atgctatttg tgggggtttt tctctcatta tttggatgga atctctttgg     3300

tcaaatgcac atttacagag agacactata aacaagtaca caaatttttc aatttttaca     3360

tatttttaaa ttacttatct tctatccaag gaggtctaca gagaaattaa agtctgcctt     3420

atttgttaca tttgggtata atgacaacag ccaatttata gtgcaataaa atgtaattaa     3480

ttcaagtcct tattatagac tatttgaagc acaacctaat ggaaaattgt agagaccttg     3540

ctttaacatt atctccagtt aattaagtgt tcatgtggtg cttggaaact gttgttttcc     3600

tgaacatcta aagtgtgtag actgcattct tgctattatt ttattcttgt aatgtgacct     3660

tttcactgtg caaagggaga tttctagcca ggcattgact attacaattt cattttggtg     3720

gagtttagtt ttaggtttta ttgtatataa aatcctgcac tgaatctgtg tctcctctgt     3780

tacctacttt tgccagtgaa atttaagttt taaaatactt tcagaatgta tttttactac     3840

tgcaagtttt tggtctttaa aatgtcaagt agcatctctc tctttctctc tgtctctttc     3900

tgtttctctc tccagttttt tttttttttt taatttccat atgggctaaa gaatccaaat     3960

attttaaaaa tctgtctctc ttttcttctc tcataaagtg aattattcct tttttttgtt     4020

ttatgtaagt gtatatattc ttagtttttc ttgaaatcat tgtaatgtta actttgttgt     4080

ttcaaatatc ttggtgattg cttcattatc tcttcaacaa aaaaaacctt taattttgcc     4140

attgaaactg tagaactatg ccatgctttt attagaagca gtgctctgtg ttaacaacaa     4200

gaatggtgta attagaattg ggatgtggat atttactgta tgacaacaca tttacagttc     4260

tgtaatgcaa ggatgcagtt taaaaatgtg aagtagtgat ggtttttgaa ataagcttta     4320

aaatataggg atcttgaagg ctccctgggg taactatttt ataacttaga taaaatggct     4380

agtcatatct gtgtgtttgt aaagttattt ttttaatatt ttaagattac aattttaaca     4440

aatgtagaaa tgagccaaac tatttaaatt ttaaaacagt aaaacaaaat gaaacttaat     4500

agctcacaaa attccagtcc atgtttcatg acttatttta gtcaatgaat tttctattta     4560

tactaaacat atggacattt taaatgtgtt tctaatattt ttgattatct ataatgtgcc     4620

tgtcttcaat tcacaagatt gggttataac aattatttgc cagattaaca ctagggaatt     4680

atttgataac cagcttatct tatcagtagt tttattgctg atcaggcaaa aatagttttc     4740

caaagttatt tttaataaag tatatacaaa attcttatat attactagtc atgataaagt     4800

aaattaagca gtttttaaaa cttagtgtga gtttgttcat cacaggtctg atatgagttt     4860

aagggatttc gcactccctg aatcagagaa gtaagacccc ttccttagat tcctgttata     4920

cattttttaa aatgtagagt ttgttttgga gacattttca gtgcattgtt attgccatat     4980

ttatataata tgactattct aaaggctgtg aggccatggg gtattggtta agttgcttgc     5040

ttttgctttg tccattttca tcattttaaa atgggggata ataacagaac ttgtttccta     5100

gggccattgt aagtcacttg aataaaaaat agttttgaag catgagagtc atacagagcg     5160

gtccacctaa aaggcactcc tgataataat aaatgatttt aaacaagtaa aaaa           5214


<210>  1392
<211>  2824
<212>  DNA
<213>  homo sapiens

<400>  1392
gaactttttt aaaaattaaa tttttatttt gagatcactg tttgtgttca gttgtaagaa       60

acaagagaga ttctgtgtac cctttaccca ttcctccatg ttgcaaaact agcacaatat      120

caccgccacg gtagacgcag tgaggccata agacatttcc gtcagcaaaa gggtcacttc      180

ttgtgcccct ttagaaccac acccacccct gccttccaac tattaatgct ggcaggactt      240

agccagaccg caagggcgcc tactccgaac aaggaagagg gtcaggcgct gggagggcga      300

ctgcaagcgg acaggcagca cctgcgacca cggtacttgg ggacaccaca aaagtccgca      360

gagcaggcac cgcggcactt ccgcgagcgc cgcaggccct gcccctttcg ccgtcgccga      420

ccaattgccg cccgaagacc gaaccgcttc agcggagggc cggaagtgag ccgcagcttt      480

tcctttctgc caccgccttg tccaagatgg cggacctcca ccgccagctg caggagtacc      540

tggcgcaggg gaaagctggc ggcccggcgg ccgcggagcc gctgctcgcc gcggagaagg      600

cggaggagcc cggggaccgg ccggcggagg agtggctggg ccgcgcgggc ttgcgctgga      660

cgtgggcgcg gagccctgcg gagtcggcag cggccggcct gacgtgcctc ccgagcgtga      720

cgcgcgggca gcggctggcg gcgggcggcg ggtgcctgct gctggctgca ctgtgtttcg      780

gcctagccgc gctctacgca ccggtgttgc tgctgcgcgc gcgcaagttc gcgctgctct      840

ggtcactggg ctcggcgctg gcgttggcgg gaagcgcgct gctgcggggc ggcgcggcgt      900

gcggacgcct gctgcgctgc gaagaagcgc cgtcccggcc cgcgctgctc tacatggcag      960

cgctgggcgc cacgctgttc gccgcgctgg gccttcgcag cacgctgctc acggtgctgg     1020

gcgcgggcgc gcaggtggcc gcgctgctgg ccgcgctggt tgggctgctg ccctggggcg     1080

gcggcaccgc gctgcgcctc gcactgggtc gcctgggccg cggcgccggc ctcgccaagg     1140

tgctgcccgt gtgaggacct cgcgccctcg ccgctgggga agtacgcgga gccagcgccg     1200

tcggagaccg cgccggccga gctgaggact gcacgccgct gtgcggaagc ccgtggcgaa     1260

ggccctgccc taacagcctg cgagtctaat ccgggagcgg ctgctgccag cggaggcgac     1320

agcagcgttg ggagctcctc gatgtcagct ttttgtgctg gacttggcac acgctctgaa     1380

aactgagatt ttgtcattga actggtgaca ggatgtgaga cggttattag aagttgcttt     1440

cgaagtaact gtggtcttag gttcggctga gtaaagaaaa aggatttttc ttcgagttag     1500

ctgctcttgt gatttttctc aggctgtttt gtcattttaa aatccagtgg tagatgtagc     1560

ttagcgacgg tagttttttg ttttggctat actaagactt ggaaattatt ctctccagtg     1620

tcagcgaatc cagaagggta tcagattaaa caccgaattc agccactgga cttttaaaag     1680

tacttaagat ggtttatctc gggttttttc ttcagttaac aaaatcataa atatggtgcc     1740

ttataacatg aaaggaaaat tagttgtgta tttcacgacg aaagcgacgg accaaaagaa     1800

atttcctgcc ccaagaagca tgggatccag gaaggggcgc gtagatgctt aacggtctct     1860

tcggaaatcc tgcaaataga aagataattc tagatccgga atacctgtat ctggtggaaa     1920

ccatggattt ctacaagctc gaattattcc tcattgtata gcctgctttg taaactagtt     1980

tacaatttgc aggctgatct taagattttt ttatatctaa ttgctgctgc cttcatttta     2040

ggttcagcag ttacttttaa ctaccttaat ttattgccag aaggtatgag cctaacattc     2100

tgatgagtcc agaaaactac gttttgtcag tagcaataca ctaggaagta aaatatattt     2160

agaatttaaa cattgtgtgc cagtggtcct cgcgcttgac tgcacatcag ttacttgaag     2220

agccacacct cagatcaatg cagtcagaac ctgggaagta ggtcccagac atcaggacct     2280

ttttaaagct ccccaagtga ttctacgttc cccaagtttg aggaccactt ttctgtgcat     2340

tggcttgcac aatttgaaaa taatgctttt cctgagctgg atcccagtgt tgccttaaca     2400

gggtgtctgt cgtgccgcag tagagcactg ctgcttcctc caaccccaaa atttatgttc     2460

ctaagtaagt caggtcccta agccccgtcc caagaagtga cacaagtggc caacatccac     2520

actgtaggct tgcaggctac ccgccctgag atttggtaaa gaacactgcc ttgttcccca     2580

tcagtaaaca aggttaccta cctcaggagg ctgcttgtga gagagcaaat gcagtatctt     2640

cagaatgatt tattttttta attaattgta aagacttgtg ccattggctg ctctttctag     2700

tcccctaaat ttctgttcta gttttaaatt tctctagaac ttgcaatagt tgggggtttt     2760

ataatgatgt tttacaatgt ttatttctta aataaaaact taaaaattca aaaaaaaaaa     2820

aaaa                                                                  2824


<210>  1393
<211>  1771
<212>  DNA
<213>  homo sapiens

<400>  1393
agtgcgctgt gctcgagggg tgccggccag gcctgagcga gcgagctagc cagcaggcat       60

cgagggggcg cggctgccgt ccggacgaga caggcgaacc cgacgcagaa gagtccacca      120

ccggacagcc agcacatcca cgatggagcg tcttgtcgcc cgtgggacct tcccagtact      180

agtgcgcacc agcgcctgcc gcagcctctt cgggccggtg gaccacgagg agctgagccg      240

cgagctgcag gcccgcctgg ccgagctgaa cgccgaggac cagaaccgct gggattacga      300

cttccagcag gacatgccgc tgcggggccc tggacgcctg cagtggaccg aagtggacag      360

cgactcggtg cccgcgttct accgcgagac ggtgcaggtg gggcgctgcc gcctgctgct      420

ggcgccgcgg cccgtcgcgg tcgcggtggc tgtcagcccg cccctcgagc cggccgctga      480

gtccctcgac ggcctcgagg aggcgccgga gcagctgcct agtgtcccgg tcccggcccc      540

ggcgtccacc ccgcccccag tcccggtcct ggctccagcc ccggccccgg ctccggctcc      600

ggtcgcggct ccggtcgcgg ctccggtcgc ggtcgcggtc ctggccccgg ccccggcccc      660

ggctccggct ccggctccgg ccccggctcc agtcgcggcc ccggccccag ccccggcccc      720

ggccccggcc ccggcccccg ccccggcccc ggccccggac gcggcgcctc aagagagcgc      780

cgagcagggc gcgaaccagg ggcagcgcgg ccaggagcct ctcgctgacc agctgcactc      840

ggggatttcg ggacgtcccg cggccggcac cgcggccgcc agcgccaacg gcgcggcgat      900

caagaagctg tccgggcctc tgatctccga tttcttcgcc aagcgcaaga gatcagcgcc      960

tgagaagtcg tcgggcgatg tccccgcgcc gtgtccctct ccaagcgccg cccctggcgt     1020

gggctcggtg gagcagaccc cgcgcaagag gctgcggtga gccaaagccc aaagagcccc     1080

gagggaacct gccggggcag cggacgttgg aagggcgctg ggcctcggct gggaccgttc     1140

atgtagcagc aaccggcggc ggctgccgca gagcagcgtt cggttttgtt tttaaatttt     1200

gaaaactgtg caatgtatta ataacgtctt tttatatcta aatgtattct gcacgagaag     1260

gtacactggt cccaaggtgt aaagctttaa gagtcattta tataaaatgt ttaatctctg     1320

ctgaaactca gtgcaaaaaa aagaaaaaag aaaaaaaaaa ggaaaaaata aaaaaaccat     1380

gtatatttgt acaaaaagtt tttaaagtta tactaactta tattttctat ttatgtccag     1440

gcgtggaccg ctctgccacg cactagctcg gttattggtt atgccaaagg cactctccat     1500

ctcccacatc tggttattga caagtgtaac tttattttca tcgcggactc tggggaaggg     1560

ggtcactcac aagctgtagc tgccatacat gcccatctag cttgcagtct cttcgcgctt     1620

tcgctgtctc tcttattatg actgtgttta tctgaaactt gaagacaagt ctgttaaaat     1680

ggttcctgag ccgtctgtac cactgccccg gcccctcgtc cgccgggttc taaataaaga     1740

ggccgaaaaa tgctgcaaaa aaaaaaaaaa a                                    1771


<210>  1394
<211>  2104
<212>  DNA
<213>  homo sapiens

<400>  1394
ctctgccgag cctccttaaa actctgccgt taaaatgggg gcgggttttt caactcaaaa       60

agcgctcaat ttttttcttt tcaaaaaaag ctgatgaggt cggaaaaaag ggagaagaaa      120

ccggcaccct ctctgagagg caacagaagc agcaattgtt tcagcgaaaa aagcagcaag      180

ggagggagtg aaggaaaaaa gcaaaaaagg gggcgacacg caagtgcctg taggggtgaa      240

aggagcaggg accggcgatc taggggggga tcagctacaa aagaaactgt cactgggagc      300

ggtgcggcca aggaggaagc agtgctgcca ggctctgctc cagggcacag ctggctggcg      360

gctgccctgt ccgcagcaaa ggggcacagg ccggggaccg cgagaggtgg caaagtggca      420

ccgggcgccg aggctgctga gcgctcgccg agacggcgac cggactggct gccccggaac      480

tgcggcgact ctccctactc agaacttggc ctacgtttcc caggactctc cccatctcca      540

gaggccccca caaaaccggg aaaggaagga aaggacagcg gcggcagcag ctcaatgagt      600

gcctacagca gaaagcctga acgagctcgg tcgtaggcgg gaagttcccg ggggggctgc      660

ccagtgcagc cgcaatgctg ccgcgagctg ccccagcagt ccgggctccg tagacgcttt      720

ccgcatcact ctccttcctc gggctgccgg gagtcccggg acctggcggg gccggcatga      780

cgggcttctc gggggcccgc cgcacgcccg gcagcctccg gagacgcgcg ccgagcccgg      840

ctcccacggc ctctgaggct cggcggggct gcggctgcct ggcgggcggg ctccggagct      900

ttcctgagcg gcattagccc acggcttggc ccggacgcga ccaaaggctc ttctggagaa      960

gcccagagca ctgggcaatc gttacgacct gtaacttgag ggccaccgaa ctgctactcc     1020

cgttcgcctt tggcgatcat cttttaaccc tccggagcac gtcagcatcc agccaccgcg     1080

gcgctctccc agcagcggag gacccaggac tatcccttcg gcgagacgga tggaaaccga     1140

gccccctgga ggacctgccc ctgcagttct gcctcacacg gctcaagtca ccaccgtgaa     1200

caagggaccc taaagaatgg ccgagccttg ggggaacgag ttggcgtccg cagctgccag     1260

gggggaccta gagcaactta ctagtttgtt gcaaaataat gtaaacgtca atgcacaaaa     1320

tggatttgga aggactgcgc tgcaggttat gaaacttgga aatcccgaga ttgccaggag     1380

actgctactt agaggtgcta atcccgattt gaaagaccga actggtttcg ctgtcattca     1440

tgatgcggcc agagcaggtt tcctggacac tttacagact ttgctggagt ttcaagctga     1500

tgttaacatc gaggataatg aagggaacct gcccttgcac ttggctgcca aagaaggcca     1560

cctccgggtg gtggagttcc tggtgaagca cacggccagc aatgtggggc atcggaacca     1620

taagggggac accgcctgtg atttggccag gctctatggg aggaatgagg ttgttagcct     1680

gatgcaggca aacggggctg ggggagccac aaatcttcaa taaacgtggg gagggctccc     1740

ccacgttgcc tctactttat caattaactg agtagctctc ctgactttta atgtcatttg     1800

ttaaaataca gttctgtcat atgttaagca gctaaatttt ctgaaactgc ataagtgaaa     1860

atcttacaac aggcttatga atatatttaa gcaacatctt tttaacctgc aaaatctgtt     1920

ctaacatgta attgcagata actttgactt tcttctgaat attttatctt tccttggctt     1980

ttcccttgct tccccttttg ccaatctcaa cacccaagtt gaagactttg tttttaaaat     2040

ggtttgtcct gatgcttttg tctaattaaa acactttcaa aacaggaaaa aaaaaaaaaa     2100

aaaa                                                                  2104


<210>  1395
<211>  1273
<212>  DNA
<213>  homo sapiens

<400>  1395
ccttgagtct ccacacacac tcctcacaga gatctgtagc gtaggtacgt gacagctctg       60

cctacatctg acgtccggag tcattaacca ggaatgtatg tgtgtctgtg tgtctctctg      120

tggagtcgtc agaattcttc ataggggtta agctaaaaaa gcgaggcgag gagcccctct      180

ccaatggctc agttttgctg aataatcacg tgtgaatcga ggggcgggct tttggcaggc      240

agatcttact agtatttact accaagctct actccagatt aaccatccca gtccttctgt      300

cagtctccga tgccatcatg cagcctggtt aggagcaaag gaaaggggaa aaagaaaaac      360

gactaattca tcttttcctg atcgtcagga ccctaaagaa tggccgagcc ttgggggaac      420

gagttggcgt ccgcagctgc caggggggac ctagagcaac ttactagttt gttgcaaaat      480

aatgtaaacg tcaatgcaca aaatggattt ggaaggactg cgctgcaggt tatgaaactt      540

ggaaatcccg agattgccag gagactgcta cttagaggtg ctaatcccga tttgaaagac      600

cgaactggtt tcgctgtcat tcatgatgcg gccagagcag gtttcctgga cactttacag      660

actttgctgg agtttcaagc tgatgttaac atcgaggata atgaagggaa cctgcccttg      720

cacttggctg ccaaagaagg ccacctccgg gtggtggagt tcctggtgaa gcacacggcc      780

agcaatgtgg ggcatcggaa ccataagggg gacaccgcct gtgatttggc caggctctat      840

gggaggaatg aggttgttag cctgatgcag gcaaacgggg ctgggggagc cacaaatctt      900

caataaacgt ggggagggct cccccacgtt gcctctactt tatcaattaa ctgagtagct      960

ctcctgactt ttaatgtcat ttgttaaaat acagttctgt catatgttaa gcagctaaat     1020

tttctgaaac tgcataagtg aaaatcttac aacaggctta tgaatatatt taagcaacat     1080

ctttttaacc tgcaaaatct gttctaacat gtaattgcag ataactttga ctttcttctg     1140

aatattttat ctttccttgg cttttccctt gcttcccctt ttgccaatct caacacccaa     1200

gttgaagact ttgtttttaa aatggtttgt cctgatgctt ttgtctaatt aaaacacttt     1260

caaaacagga caa                                                        1273


<210>  1396
<211>  2486
<212>  DNA
<213>  homo sapiens

<400>  1396
gcgagagttg cttttgcgcg cgaactgtaa gtgccagggt ctcagggtca ggtcgcggct       60

ggtcactgtg caggcgcttg ggtgacgcga cgatctcagc ggatctggtc accttcgtct      120

ccccgccatg gagacctcag cactcaagca gcaggagcag cccgcggcga ccaagatcag      180

gaacctgccc tgagacaggg tctcgctctg tcgcccatgc tggagcgcag tggtgtgatc      240

acagctcagt gtaacctcaa acattggggt tcaagccatt ctcctgcctc agcctccgaa      300

gaactgggac ttttagaggc gagctaccaa gcccatcctg taaccatttt aaaatgtaca      360

attcagtggc attaagtaca ttcagaatgc agtgtactgt tgtggagtct tcccgctatc      420

tagttccaaa atttcatcac cccaaatgga aatcctttac ccattgacag ttactcccca      480

ttctcccctt cctctagccc ctggcaacca ctaatctgct ttctatctat ggatttgcct      540

attctggaca tttcatggtt gaaaaatacc ggccacagac cctgaatgat ctcatttctc      600

atcaggacat tctgagtacc attcagaagt ttatcaatga agaccgactg ccacacttgc      660

ttctctacgg tcccccaggg acaggcaaga catctaccat cctagcctgt gcgaaacagc      720

tatataaaga caaagaattt ggctccatgg tcttggagct gaatgcttca gatgaccgag      780

gaatagacat cattcgagga ccgatcctga gctttgctag cacaaggaca atatttaaga      840

aaggctttaa gctagtgatc ttggatgaag cagacgccat gactcaggac gcccagaatg      900

ccttgagaag agtaattgag aaattcacag aaaataccag attctgcctc atctgtaact      960

atctgtcaaa gatcatccct gccttgcagt cccgctgcac gaggtttcgg ttcggtcccc     1020

tgactcctga actcatggtt ccccgcctgg aacatgtcgt ggaagaagag aaagttgata     1080

taagtgaaga tggaatgaaa gcactagtca ctctttccag tggagacatg cgtagggctc     1140

tgaacatttt gcagagcacc aatatggcct ttgggaaggt gacagaggag actgtctaca     1200

cctgcaccgg gcacccgctc aagtcagaca ttgccaacat cctggactgg atgttgaatc     1260

aagatttcac cacagcctac agaaatatta cagagttgaa aactctgaag gggttggcac     1320

tgcatgatat cctgacagag atacacttgt ttgtgcatag agttgacttt ccatcttcag     1380

ttcgaataca tttattgacc aaaatggcag acattgagta caggctttct gttggcacca     1440

acgagaagat ccagctgagc tccctcattg ctgcatttca agtcaccaga gacctgattg     1500

ttgcagaggc ctagatgctc tgagggccat tcacaattct cagggctcag cagtgatggg     1560

agaacagagg acagttccag gataaactgc tgcctggggc tgtgggatga atcagtcacc     1620

ccgaatcttg gaaaaacccc cttccaggag aggatgggca ggcatttaaa aagtaccatt     1680

tttgtggttg tttggagcag ggatgtacaa aataatttta atgtattaac tcatactgcc     1740

tgtcttttat aggggaaaaa aataaccttt tttattttaa agttataagg tttttacctt     1800

ttagttgctt ggatgacagg gaattagcct accccatttt ggtctggaac agaagacttt     1860

caaatttaat atggtccaag tgtcttccta ctcaaggtaa acattatctc caaaattaca     1920

tttatgattc taatatttgg cattgtgtct gtatctaatt taaacagatg ttaatggacg     1980

tctggccgaa actattatac ttttataaga tgagctgaat cctcttactt taaaaactgg     2040

tctttttatt taccctctgt ggtagaagag tcaccagcag gttccaaatt gatgtgtatg     2100

ataggaaaaa aaccttaatt ttaaatataa tatagagcct taaactatgc cactgggtgg     2160

cagaggctgt ataaaacgca cttgttttca tgcaggagcg gggcaagtaa ggttgagcct     2220

gactgtaaac ctagaactgc ggaaggactg ggacttttgt acaaatttca catttatttt     2280

acagcaatca tgctgcattt gtgttagtgt tctttataat aaaaaacaaa gcagcctcct     2340

ggctggctgt gttacaagtg actcttcctt agacagctag aaagatgctg actttgtcaa     2400

acttgcattt atatgaaaac cttctgtctc taatatcaca gaataaactt tctttagatg     2460

ctgttcttta taaaaaaaaa aaaaaa                                          2486


<210>  1397
<211>  8133
<212>  DNA
<213>  homo sapiens

<400>  1397
agcggaccga gccgcagccg cagccgggcg gcgggcgaga ggcggcggcg gcgggcgggc       60

cgcgggcagt cagtcgggcg gcggcggcgg cggcggcggc ggcgatgcgg cggccccgct      120

gagtccgccc gctcctggcg ccgggagcca gccgcgcgag gcggcccggg ccgggcggca      180

gcatgcggag cggcgaggag ctggacggct tcgagggcga ggcctcgagc acctccatga      240

tctcgggcgc cagcagcccg taccagccca ccaccgagcc ggtgagccag cgccgcgggc      300

tggccggcct gcgctgcgac cccgactacc tgcgcggcgc gctcggccgc ctcaaggtcg      360

cccaagtgat cttggccctg attgcattca tctgcataga gaccatcatg gcatgctccc      420

cgtgtgaagg cctctacttt tttgagtttg tgagctgcag tgcgtttgtg gtgactggcg      480

tcttgctgat tatgttcagt ctcaacctgc acatgaggat cccccagatc aactggaatc      540

tgacagattt ggtcaacact ggactcagcg ctttcctttt ctttattgct tcaatcgtac      600

tggctgcttt aaaccataga gccggagcag aaattgctgc cgtgatattt ggcttcttgg      660

cgactgcggc atatgcagtg aacacattcc tggcagtgca gaaatggaga gtcagcgtcc      720

gccagcagag caccaatgac tacatccgag cccgcacgga gtccagggat gtggacagtc      780

gccctgagat ccagcgcctg gacacgtgag gacctgcctg gatcctcctc cctcccgtcc      840

tcgtgcctgt ctctcagtca agttttcttt cccttgtcct gtcagatttc catgtgattc      900

agttgaattt tgtcctcttt ggtaaaagtt cattttggga aagggtttcc cgagtggccc      960

agtgggcggg tccgcggtgg agttgggagg cccacgttcc tcagcgtttg gggctgtgga     1020

gcagccggcg tcactgccca ggtccacttg aggtcttacc tgccctgaag cacaggcttc     1080

ctttgactct gagccacctt gtcgtgtgta tttgtaacaa gactttggat taaatggggc     1140

tgctaagagg ggggaaatat gaaggaatga agggacagca ttggaacggt cagtcggcag     1200

tggttctcag gcagccttag gcaccacctg ctccaagtca gtgttgagtc tgcgtgctgg     1260

gatccagccc actcctcatc ttccatgcca gggcccccag gcagccagca ccagcccaaa     1320

ggccacaggg ctggggaaag ctgatgtcct gttaggatgg ctcccaggga cctctgactc     1380

aaggaagggt gaccttttgt ttcctactct gctgagaaat cacttgattc ttcctcaaat     1440

gaatcacctt cctgaacccc agattcttct ccaggaatat gggggccatc ttgttatggg     1500

gactatcttg ttttccagtt tcctgcctac cctaaatact ttgaggctga attgcagatt     1560

ttcagtcatt ttaccttctc aggtaaaagc catgaaagaa acaagcctac tccaccagcc     1620

aaagcacttg cccatttgct ggcttcatga accgcaggtg ggaggtgttt gtgttaaaaa     1680

acagcatgca cacgcgtgcg cgcacacatg cacacacaca cccctctatt ttagggatgt     1740

gtgctaattt tctaaatgcc tgcaaagagt tctaaaatga ttctgagcag attcgtctag     1800

gatttgaaaa tacttgaatt tgcaccagaa cacacccttc cacccatgtt tcagaaggca     1860

ctaattgtcg ctttgggcgc ctcagtgtca taactgtaga catcattctt gggagttgtt     1920

ggggggaaaa atcctagcta cttaaggttt ctgattgatt cttgataaag tgaagattat     1980

tgtgtgtggt gaatgagttc agtgagtccc catgatgcag tagttttttt aaaaaattag     2040

agagtaatta tatcttttat ggaaaaaagt tgttttagtt tgtcaggttt tccctctttg     2100

aactgttttt aatgtttaca aacctcactt tagctctaac attttgtgtt tagccctcac     2160

caaaaagcac ttactgtggc aggaagattt tgcagtaaca tggagaaatc cccaagatca     2220

agtgctgaca aatgttgaca gctttagcag cgtactgtgt aataaataac tccgaggggg     2280

cggcgggggg tctgtgcaag aaagcgtcac cttatggaca tgtggcgtct cattccccag     2340

aaaaggacag catctgagct cacagtgttg atcaggcaac actgctgggc tgggggtcgg     2400

agttggggtt agcttcctgc accaacacct tcagtacgat ctgagttggg agcagtgtcc     2460

caggctatgt ggctgagcac cacgtctgcc tcaggggctg accctgctag cctgttaaca     2520

actcgtctcc cctctgctcc cacagagagg gcagccaggc cagctcacag ctgggtgtgc     2580

tgcctgtcag gtctgttgag tgtgtttgca aagtcaaaat tgggcttatc tctctttgag     2640

agttcctttt aaaatagggc cacaaaggct cagccttgca ttaaatgggg cccacttgga     2700

aggaccatcc tgagctttat cagaaatctc ctgctgggaa tcatgttact tggcccccaa     2760

aaaaggccat ctttgaagtg agattgaaaa caagaacacc attcaggtgg gcttgttgcc     2820

caagttttcc cagctcactt cagtaaaacc acttgatcat ctggtgaaag aggggggcag     2880

gtggttggcc tcctgaggat atgttgtcag ctgcaagaaa tagttctgaa gtcactgaaa     2940

ctaaatgcag atgaatgacc aaaaaggatg acacgccaga gagtgactta ggagttaatt     3000

tgcatcttcg tgatagactc ttcagaatta tttatgtccc tgtaactatt taatatcctt     3060

tgtgccgtga ggctcctcgg tggttttgta aatgttctcc ttgtatttaa ttaactccca     3120

ctagaaccgg aagtggtgct atggacgctt tctagttgat gtaatgtgtg gttgcacatg     3180

tcatcatgta tagaccacgt ggtgacgaaa gttctggagg gaatagggtt atccaaggtg     3240

aatatgaaga cgcctatatt tttcttatat tgcctctata tgcaaacaga agacaatcga     3300

tatctggggg ccttaaaatg acctcttggc aaattgaagg aagcgttttt gcgtttaata     3360

gtttcaatag ggaccaatat cagtttggtt tggggcattt gaaggctgag cgaccttagt     3420

ttttctcagt gttctggtgg gacgatattg gttttcacat ttaaagcaaa acttgaagaa     3480

actgcagttg ctgtgtgcat ttgggttttt tcctggacac tgtacagctg aaaccctcaa     3540

gcatttggtg gaacctctgg tggttttaga tggatgcaaa cactgatgtc ctcagagaaa     3600

gtttattttg gcactgattg ggtggatttg gtattttttc cctctgattc tctttgatat     3660

ccttctttca cactgctgaa ggcatgggag ggaaatatgt tttccctgcc ttaaagaggg     3720

attacagtca tgaaaggctg gagatacttg ttggccccac ataaagctgg gaagaacaga     3780

tgcagtttca gattaaaatc tcgtcagaga agtttgattt gaagtaaaca gccatccgag     3840

ggaggtgact tttgtctaca gaaaaagcaa gaatgtggca gcctgcacag ccccaataca     3900

catcttcctt ggcaatgtga gctgaagcca gcatgggcaa gtccggccca gctctgagcg     3960

cttggccctg ggaagccagc ggcaccccca gcccttcggg ccctgttact gtcccctggc     4020

aggaaggctc acgcctgtgg gcagccaggg aatgtgtctg acctccaccc tatgtcgggt     4080

gcttctggga cagcttcgtg actcagttga aaacattctg actctcttca agtttgcagt     4140

tacatctgtg gttcttggaa gctgtcctag tgagtcagcc ttgggttaag cctgaggaga     4200

ccaagctcca acacctttgt gcactcatgt acgtgaattc ttgcttgcag tgaatgagac     4260

ctgaacaacc ctagtgggtg ccatgtcctg cgtgtggccc aggcgtacct tttcttgtag     4320

attcacatga gaaacccgtc acctatccat gtgctctgag aggtggactg aggtctaatc     4380

cctttctgtg ccagattttc tgtgggttgg tcttagcacc taggagatga atagagcatg     4440

gagacacctg aacaatttag tgattctgca aggcagtgat gatttaaggg ttcctattgt     4500

ctcatctgtg ttcaaaacaa aacagtcatg aagtctttgt gccactgcct gactgtcatc     4560

ttctccagat cttgtttaca gagtaataat gacgttaaac aggtatcaga aaggggaaaa     4620

agtttctagg ccaagagctg ctggtggatt ctcttgagca gaataacaag ttgcttcctg     4680

ctccagggac tgccattagc ttgtgaagtc tctaggtgcc ttgttatttc ctagtgaagt     4740

tgcagaatcc agggtttttt ccaggtttgt cttattttat cagcacccac gtccaggccc     4800

aacagcttgg taggctggtg aggtccacac acggccaggt ctgggagata agggaggaag     4860

cagtggcctg gaacacccca cctgtctgct atcagcacta gacagctcag gctgtcttgg     4920

aaacgtgtac tttgttaact gccttcctgt cctcttgtct ttgaaagctg tctcgcgttc     4980

cacagtcagc ttgagggcaa gagtgggatg ctggggacag gtctttcccg tcctgtgggt     5040

gagctcctgg catctggctc aggaacatgt gggtccagca ggtgactctg aagctggctt     5100

ggctgccatc tcagacagga cgcaggcctg acaccctcag cttttagctt tgtaaacttc     5160

cctggcgctt tgtagaatct tgtgtttctt ctcttctcag cagatatcat tcaagtcaca     5220

agaactgtct ggttgagaaa gtaatttaaa atatttgacc ttttatgttt cttttattta     5280

gaaactgtga gagaaaatac cgtcaatatc tgttaggtct agaaaaattt tcttccgaaa     5340

gtgaatgttc tgtttaattc ttcttcatgc aagtgagtgg cattttgtac actctttagc     5400

ttgaagcgga gtgggtccta ttgtattttc ccttcttttg tctggaatat attctttttc     5460

catttggata cagtttttca acctttggga tttttttttc ctttctagtt tttcctactc     5520

cacaaacgta acagtaagga aaaaatcacc cacaaacctg ctgagtttga atcactggca     5580

acttgcctag aaaagttcag atgatgggtc cttgaactgt gtatctattt catagggtaa     5640

gtttgttgtc tatgtttgtt tttttatgct gaggctttaa ttcaggtgac ttgctatcta     5700

gacacctggg gtggcgtgtt ttctttggga tgcataatac acaaaggcca gggagccttt     5760

ggcttggacc cccagggagc tattgaaact tttaaagttt gagtttagga gtaagaacat     5820

atctcagacc accttagtca gctttgctga tgggatttag ggccaggtca gagtttcttt     5880

tcataactgc ctgaaaagag agatggtgtg aaacaagatt ctgataatgg tttgtgtgag     5940

atttgatcat agtctaaaac tatcacgtct gagttgcctt aggatgacag tgctgacacc     6000

cagtaggaag tatcccattt ttatcaggaa agtcagtcac gcgtagggat ggtgaggaga     6060

cgcgtaggga tggtgaggag gggagaggag ggagacctgc tggtgccctt gcaccagggt     6120

gaggcctgac tcacgctgct tccccccaca ggccctgctt tgcttgcctg ctttttccag     6180

aatcgatttt gcaagcttca agattctgtt cccctcttcg cagaagtgag gaaggcaaat     6240

actcagggtt tgaagggaga cctggccggc ctgagggctg gcagatgtga gggcaggaca     6300

cctgggatgg actcgtaggc tgacccaggc ccaaaggggg ctgcctgttc ccaactcttt     6360

cactctgtaa cccattttaa aatgagtttt tgaatcttgc ctcaaattga cctacttgga     6420

taaaatcagt gcttttccta acttgatttt gtttgacgtg gttccctcta agagaatggt     6480

aggaattgaa actatttgta tatgttgaaa tttgtagggg ttcaggaacc catggcagaa     6540

acactaaact atttatttac aagtatgact attttttttt caaagtaggc aattctttgt     6600

atattttaag gcaaataatc acttcacctc tggtgccttc catgcgtcgc ataagcactc     6660

ttgtcaatca tggaattgga aaaaaagatg tacatttagt taaacaagat aacactattt     6720

ttgtagcatg attttagatt gtgtcctttt aatattgttt tcaacaatgg tagttttgag     6780

gttttggcca ttttctcttt acacttcgta tgtattttaa agaagaaaaa aaacaaaaaa     6840

aattccctgg ctattcctct ttcctctctg ctgctgcttc tcctgcatct tgttcctgct     6900

tatttaaata gtctgagagt aagagtatat ttctgtgaaa taattataag tcagtataat     6960

tgcatttggc attttttaac cacttgctca gtttggagcc actgctcacc tcaaacagta     7020

caaagaaagt ggttccatat tttacaaaca gaagagtagc atcagagccc tgacctcctg     7080

tctttgggtg taaaatggtg agaggccggt gtccggctcc ttcccctgtg gtttgggctg     7140

gtgaactgag cccaagtgta ttctctggcc tgggcccctt ccagaatcag tgcgagcgtc     7200

ctgcagaggc atggccttcc tgccactgca gagtgggaag cttcctgggg gacctcagcc     7260

agctccgggg ctctcatctt ccactcggat ctcagattgg ttcgttgtgg atgctctggc     7320

taggctcggc ggccttttcc aggcttcagg cctgaacaaa acaggctgtt tgctgtgagg     7380

agctagatga caccaagaca cagacacgta ctcttcaccg gctccttttg cttctccttc     7440

ctgcaggacg tgagttatgt ctggtcccaa aacccttgag taaactagct gagccattgc     7500

aaatgaaggt acagatggat tgaaacataa aattgtagct tttggtgtcc ttctgaaggg     7560

tcagaatatg taattatttg ataaccaagg aagtcaagtc agatggctaa gtagtaactt     7620

tccaatatga tttctccgtg gtacttcacc tggtggcact tttggggggc aatgttaaca     7680

actatcacat tttactcatc aagtctcttt catttcggca gtttaaagac acaactgtgg     7740

gctttctgag gcgatgcccg ttgggcaaac ttaggtttat gtgtttggtt tttcagctga     7800

cgtggaagcc ctgggtgggc gtcccctggc tggcctggct tttgggttca agtctgtatg     7860

tatggagtgg gttggggccc caaagctttg ctgctattga tttgtccccg acagcaggca     7920

aagcctcaca ttgccctcaa ttttccccct ttcatttgaa ggaccagttt ttcatggtac     7980

ttgtcttgat ctttttcata gtgttcaaat ctgtattttt gtatgtagag ggaaataatt     8040

ttctcaacac taatcgttaa taactattgt attaaattgt catgaaggaa cttgtttaat     8100

aaatggacgt gtaaggaaaa aaaaaaaaaa aaa                                  8133


<210>  1398
<211>  1781
<212>  DNA
<213>  homo sapiens

<400>  1398
cggggaaggg gtggggtgga ggcgggagcg gagccgggcg ccgccggagc tgcgcgggga       60

gcgctcgctg gctggctggc tggctggctc tccgctgcgc tgcgctgcgc tccggccgct      120

cccgcggccc gtggatgggg gtgtccggct gagccccggg atccgcctcc ctccgccagg      180

acccgcacag ataaactcat cctgaaagtc gctgttgttc tcctgctgag caagaatgga      240

ggccccactg gtgagtctgg atgaagagtt tgaggacctt cgaccctcct gctcggagga      300

cccggaggag aagccccagt gtttctatgg ttcatctccc caccatctcg aggacccctc      360

cctctccgag cttgagaatt tttcttccga aataatcagc ttcaagtcca tggaggacct      420

cgtaaatgaa tttgatgaga agctcaatgt ctgctttcgg aactacaacg ccaagaccga      480

gaacctagct cccgtgaaga accagttaca gatccaagag gaggaggaga cccttcagga      540

cgaggaggtt tgggatgctc tgacagacaa ttacatccct tcactctcag aagactggag      600

ggatccaaac atcgaggctc tgaatggcaa ctgctctgac actgagatcc atgagaaaga      660

agaggaagag ttcaatgaga agagtgaaaa tgattccggt atcaacgagg agcctctgct      720

cacagcagat caggtaattg aggagattga ggaaatgatg cagaactccc cagaccctga      780

ggaagaagag gaggttctgg aagaagagga tggaggagaa acttcctccc aggcagactc      840

ggtcctcctg caggagatgc aggcattgac acagaccttc aacaacaact ggtcctatga      900

agggctgagg cacatgtctg ggtctgagct gaccgagctg ctggaccagg tggagggtgc      960

catccgtgac ttctcggagg agctggtgca gcagctggcc cgccgggacg agctggagtt     1020

tgagaaggaa gtgaagaact cctttatcac ggtgcttatt gaggttcaga acaagcagaa     1080

ggagcagcga gaactgatga aaaagaggcg gaaagagaaa gggctgagcc tgcagagcag     1140

ccggatagag aagggaaacc agatgcctct caagcgcttc agcatggaag gcatctccaa     1200

cattctgcag agtggcatcc gccagacctt tggctcctca ggaactgaca aacagtatct     1260

gaacacagtc attccttacg agaagaaagc ctctcctccc tcagtggaag acctgcagat     1320

gctgacaaac attctctttg ccatgaagga ggataatgag aaggtgccta ctttgctaac     1380

ggactacatt ttaaaagtgc tctgccctac ctaaccttgc cctttggagc agcctcgctg     1440

caggaggtca ctgagcaaga gtcattccat cacagggact gcatgagacc atgtaacctc     1500

cgacatgtat ttaaacgtgt atagcttaac ctggattaaa cacgagcaag cgcgcggggt     1560

cctttgccgt tggcttctag tgctagtaat cattggatgc atgatggggc agggccggtg     1620

atggtgcctc ccccttgctg gtgtcaggag aggggaaggc agccgctttc accgctcatt     1680

atgtagtctg gctacagccc tcaaaaacag cttatactct taagactaat tttgaaataa     1740

aaccttcatt taattaatat tcttaaaaaa aaaaaaaaaa a                         1781


<210>  1399
<211>  3713
<212>  DNA
<213>  homo sapiens

<400>  1399
attcccatgg cccgggctca ggcgtccaac ctgctgccgc ctgggccccg ccgagcggag       60

ctagcgccgc gcgcagagca cacgctcgcg ctccagctcc cctcctgcgc ggttcatgac      120

tgtgtcccct gaccgcagcc tctgcgagcc cccgccgcag gaccacggcc cgctccccgc      180

cgccgcgagg gccccgagcg aaggaaggaa gggaggcgcg ctgtgcgccc cgcggagccc      240

gcgaaccccg ctcgctgccg gctgcccagc ctggctggca ccatgctgcc cgcgcgctgc      300

gcccgcctgc tcacgcccca cttgctgctg gtgttggtgc agctgtcccc tgctcgcggc      360

caccgcacca caggccccag gtttctaata agtgaccgtg acccacagtg caacctccac      420

tgctccagga ctcaacccaa acccatctgt gcctctgatg gcaggtccta cgagtccatg      480

tgtgagtacc agcgagccaa gtgccgagac ccgaccctgg gcgtggtgca tcgaggtaga      540

tgcaaagatg ctggccagag caagtgtcgc ctggagcggg ctcaagccct ggagcaagcc      600

aagaagcctc aggaagctgt gtttgtccca gagtgtggcg aggatggctc ctttacccag      660

gtgcagtgcc atacttacac tgggtactgc tggtgtgtca ccccggatgg gaagcccatc      720

agtggctctt ctgtgcagaa taaaactcct gtatgttcag gttcagtcac cgacaagccc      780

ttgagccagg gtaactcagg aaggaaagat gacgggtcta agccgacacc cacgatggag      840

acccagccgg tgttcgatgg agatgaaatc acagccccaa ctctatggat taaacacttg      900

gtgatcaagg actccaaact gaacaacacc aacataagaa attcagagaa agtctattcg      960

tgtgaccagg agaggcagag tgccctggaa gaggcccagc agaatccccg tgagggtatt     1020

gtcatccctg aatgtgcccc tgggggactc tataagccag tgcaatgcca ccagtccact     1080

ggctactgct ggtgtgtgct ggtggacaca gggcgcccgc tgcctgggac ctccacacgc     1140

tacgtgatgc ccagttgtga gagcgacgcc agggccaaga ctacagaggc ggatgacccc     1200

ttcaaggaca gggagctacc aggctgtcca gaagggaaga aaatggagtt tatcaccagc     1260

ctactggatg ctctcaccac tgacatggtt caggccatta actcagcagc gcccactgga     1320

ggtgggaggt tctcagagcc agaccccagc cacaccctgg aggagcgggt agtgcactgg     1380

tatttcagcc agctggacag caatagcagc aacgacatta acaagcggga gatgaagccc     1440

ttcaagcgct acgtgaagaa gaaagccaag cccaagaaat gtgcccggcg tttcaccgac     1500

tactgtgacc tgaacaaaga caaggtcatt tcactgcctg agctgaaggg ctgcctgggt     1560

gttagcaaag aaggacgcct cgtctaagga gcagaaaacc caagggcagg tggagagtcc     1620

agggaggcag gatggatcac cagacaccta accttcagcg ttgcccatgg ccctgccaca     1680

tcccgtgtaa cataagtggt gcccaccatg tttgcacttt taataactct tacttgcgtg     1740

ttttgttttt ggtttcattt taaaacacca atatctaata ccacagtggg aaaaggaaag     1800

ggaagaaaga ctttattctc tctcttattg taagtttttg gatctgctac tgacaacttt     1860

tagagggttt tgggggggtg ggggagggtg ttgttggggc tgagaagaaa gagatttata     1920

tgctgtatat aaatatatat gtaaattgta tagttctttt gtacaggcat tggcattgct     1980

gtttgtttat ttctctccct ctgcctgctg tgggtggtgg gcactctgga cacatagtcc     2040

agctttctaa aatccaggac tctatcctgg gcctactaaa cttctgtttg gagactgacc     2100

cttgtgtata aagacgggag tcctgcaatt gtactgcgga ctccacgagt tcttttctgg     2160

tgggaggact atattgcccc atgccattag ttgtcaaaat tgataagtca cttggctctc     2220

ggccttgtcc agggaggttg ggctaaggag agatggaaac tgccctggga gaggaaggga     2280

gtccagatcc catgaatagc ccacacaggt accggctctc agagggtccg tgcattcctg     2340

ctctccggac ccccaaaggg cccagcattg gtgggtgcac cagtatctta gtgaccctcg     2400

gagcaaatta tccacaaagg atttgcatta cgtcactcga aacgttttca tccatgctta     2460

gcatctactc tgtataacgc atgagagggg aggcaaagaa gaaaaagaca cacagaaggg     2520

cctttaaaaa agtagatatt taatatctaa gcaggggagg ggacaggaca gaaagcctgc     2580

actgaggggt gcggtgccaa cagggaaact cttcacctcc ctgcaaacct accagtgagg     2640

ctcccagaga cgcagctgtc tcagtgccag gggcagattg ggtgtgacct ctccactcct     2700

ccatctcctg ctgttgtcct agtggctatc acaggcctgg gtgggtgggt tgggggaggt     2760

gtcagtcacc ttgttggtaa cactaaagtt gttttgttgg ttttttaaaa acccaatact     2820

gaggttcttc ctgttccctc aagttttctt atgggcttcc aggctttaag ctaattccag     2880

aagtaaaact gatcttgggt ttcctattct gcctccccta gaagggcagg ggtgataacc     2940

cagctacagg gaaatcccgg cccagctttc cacaggcatc acaggcatct tccgcggatt     3000

ctagggtggg ctgcccagcc ttctggtctg aggcgcagct ccctctgccc aggtgctgtg     3060

cctattcaag tggccttcag gcagagcagc aagtggccct tagcgcccct tcccataagc     3120

agctgtggtg gcagtgaggg aggttgggta gccctggact ggtcccctcc tcagatcacc     3180

cttgcaaatc tggcctcatc ttgtattcca acccgacatc cctaaaagta cctccacccg     3240

ttccgggtct ggaaggcgtt ggcaccacaa gcactgtccc tgtgggagga gcacaacctt     3300

ctcgggacag gatctgatgg ggtcttgggc taaaggaggt ccctgctgtc ctggagaaag     3360

tcctagaggt tatctcagga atgactggtg gccctgcccc aacgtggaaa ggtgggaagg     3420

aagccttctc ccattagccc caatgagaga actcaacgtg ccggagctga gtgggccttg     3480

cacgagacac tggccccact ttcaggcctg gaggaagcat gcacacatgg agacggcgcc     3540

tgcctgtaga tgtttggatc ttcgagatct ccccaggcat cttgtctccc acaggatcgt     3600

gtgtgtaggt ggtgttgtgt ggttttcctt tgtgaaggag agagggaaac tatttgtagc     3660

ttgttttata aaaaataaaa aatgggtaaa tcttgaaaaa aaaaaaaaaa aaa            3713


<210>  1400
<211>  3899
<212>  DNA
<213>  homo sapiens

<400>  1400
agtggcgtcc gttgtaagtg ctatgacaac agggcgaaga tggctcagag ttaggctgga       60

gaggggaggt gtcccttccg ctgcggccgt cgggtttctg ctacatccca ttcaccgcct      120

cctccatcct ttcctcctcg gtgtgagcag caggacttgc atttgttctc gcctgcctag      180

tgtcttccaa gggatagatg ccgtttcctc tgctggtctc tgggggtgac ggggggcgca      240

ggggagcttc ttgggggaat cactccaact ctgtggagct ggtggtgctg cctggtgggg      300

ctctctcttt gcccgggacg tggaacaact ttcagctgga ggacgagagg gaatagtgaa      360

gctaaaggtt gcttttctct gcaccgtccg ttcttgctcc ctctgctcca tcactgggac      420

cttgtcaggc gttcataaag caaaatttgc cgaacgaggg ttcgcagaaa ggtggggcag      480

agctcatctg acgtggcatc agtgtgaaag aaaatgtctt tatttaaagc ccgtgattgg      540

tggtctacta ttctgggaga taaagaagaa tttgatcaag gctgtttgtg tctggctaat      600

gttgacaata gtggaaatgg acaagataaa ataattgtgg gtagctttat gggataccta      660

aggatcttta gcccccatcc tgcaaaaaca ggagatggag ctcaagccga agatttgctt      720

ctagaagtgg atctacgaga tccagtactt caagtggaag taggaaagtt tgtttcaggt      780

accgaaatgc tacatttggc tgtgttacat tctagaaaac tttgtgtcta ctctgtctca      840

ggaaccttgg gtaatgtgga acatgggaac caatgtcaga tgaaattgat gtatgaacat      900

aatcttcaga gaacagcctg caatatgacc tatggatcat ttggtggtgt aaaaggtcga      960

gatttaattt gcatccagtc tatggatggg atgctgatgg tatttgagca ggagagctat     1020

gcttttggaa gatttctccc tggctttctt ctgcctggtc ctcttgccta cagttcccgt     1080

acagattcct tccttactgt ctcttcctgc caacaagtgg aaagttataa gtaccaggta     1140

cttgcttttg caacagatgc agataaaagg caggagactg aacagcaaaa acttggttct     1200

ggaaaaagac tagttgtgga ttggactcta aatattggag agcaagccct tgacatatgt     1260

attgtctctt tcaatcagtc ggcatcctct gtttttgttc ttggtgagag aaactttttt     1320

tgccttaagg ataatggaca aattcgattc atgaagaagc ttgattggag cccaagttgt     1380

tttctgccat attgctcagt ttctgaagga acaataaata ctttgattgg aaatcataat     1440

aacatgctgc atatttatca agatgtgaca ctgaagtggg ccacccaact tccccacatt     1500

cctgtagcag taagagtggg ctgtttgcat gatttaaagg gagtgatagt cactctgagt     1560

gatgatggtc acttgcagtg ttcatacctg gggacagatc cttctctgtt ccaagctcca     1620

aacgttcaat ctcgagaact aaactatgat gaacttgatg tagaaatgaa agaacttcag     1680

aaaatcatca aagatgttaa caaatcacaa ggtgtttggc ccatgactga gagagaagat     1740

gacttgaacg tttctgtcgt ggtttctcct aactttgatt cagtttctca agcgaccgat     1800

gttgaggtgg gaactgacct tgtcccttct gtcacggtga aggtcacact gcagaacaga     1860

gtgatattgc aaaaagccaa attatcagtc tacgtgcaac caccattaga attgacttgt     1920

gatcagttca cctttgaatt tatgagcatt ccgcgagtta tccaatgtaa atttagactt     1980

cccctaaagt taatttgcct accaggtcag ccttcaaaaa ctgcaagcca caaaattact     2040

attgatacca acaaatctcc agtcagtctt cttagtctct tcccaggttt tgccagtcag     2100

tcagatgatg atcaggtgaa tgtaatgggt tttcacttct taggaggtgc tcgaattact     2160

gttcttgctt ccaaaacttc tcaacgatat cgcattcaga gtgaacaatt tgaagatctt     2220

tggctcataa ccaatgagct tattcttcgc cttcaagaat attttgaaaa acagggagtc     2280

aaagattttg catgttcttt ttcgggatct ataccccttc aagaatattt tgagttgatt     2340

gatcatcatt ttgagctacg gataaatggt gaaaaattag aagaactctt atctgagaga     2400

gctgtacaat ttcgggccat tcaacgccgg ctactagcaa gattcaaaga taaaactcct     2460

gcccctcttc aacacctgga caccttgtta gatggaacct acaagcaggt aattgctcta     2520

gcagatgcag tggaggaaaa ccaaggcaat ctgttccagt cattcaccag gctgaagagt     2580

gccacccatt tggtgattct gctgatcgcg ctgtggcaga agcttagtgc tgaccaggtt     2640

gctattctgg aagcggcatt tctgccgcta caagaagaca ctcaagaatt gggctgggaa     2700

gaaacggtgg atgccgccat ttcccacctg ttgaagactt gcctgtcgaa gagttctaag     2760

gagcaggctt tgaacctcaa cagccagctg aacataccca aagacacaag ccaactgaag     2820

aaacatatca ccttgctctg cgatagatta tccaaaggtg gccgtctctg cctaagtacc     2880

gatgcagcag ccccacagac catggtcatg ccaggtggtt gtactacaat cccagagtca     2940

gacctagaag aaagatcagt agaacaagac tctacagaac tgtttaccaa ccacagacat     3000

ctcactgcag agacacccag gcctgaagtt tcacccctcc aaggagtctc ggaataattc     3060

aagtagagtt gtttggttga gaggaacatc cccatctcaa ggccgaacct gtgtgaacct     3120

catgccaagc acagatatag ggctggcgca ggtgcttcct aaagctcacc ttcctggaga     3180

tgacatgcat agaaagaggg gttgggactt tttacttcac taggagaact tgtaacacca     3240

tggggaagtc agctgaaact tgtcttgttt tgccaggaaa ggaagtagtt gcctttggtc     3300

atccatctgc taatagtcac agaatacagt gaaatgacat agttttgggt tagattttat     3360

aatgcaaaga ttcagatcca aaataatttc ataccccatt ttttcacaga attcttatat     3420

agtaaatgta tcaagtttaa taaagcatct cattgtcaaa taatatcttg gattttattt     3480

ataattagag ggatttatga gtgattgctc tacattattt cttcaaagga aaggaaagga     3540

attgaagact ttgctactct ctggtaagac ttgaatgtga ttattttata aataaaagaa     3600

ccactatgaa actttcatgt gatttgttct attaagctaa acgtggaaga agggaagttt     3660

tctagtattg tatgaaaatg tttaaatatt ttcaaggaag ctagtacatt aacatcccct     3720

tttcattacc ccattgggtg gcacctttta aaaatccagg ttattaaagg attcacactt     3780

tattacagtt aaaatttaag gtttttatgt gtaagaagtg aaagaaactt tgctaatttc     3840

aagttcgaat tacagttgtg agattgattt atttaaataa aaatatgcct ttgccagtt      3899


<210>  1401
<211>  4019
<212>  DNA
<213>  homo sapiens

<400>  1401
agtggcgtcc gttgtaagtg ctatgacaac agggcgaaga tggctcagag ttaggctgga       60

gaggggaggt gtcccttccg ctgcggccgt cgggtttctg ctacatccca ttcaccgcct      120

cctccatcct ttcctcctcg gtgtgagcag caggacttgc atttgttctc gcctgcctag      180

tgtcttccaa gggatagatg ccgtttcctc tgctggtctc tgggggtgac ggggggcgca      240

ggggagcttc ttgggggaat cactccaact ctgtggagct ggtggtgctg cctggtgggg      300

ctctctcttt gcccgggacg tggaacaact ttcagctgga ggacgagagg gaatagtgaa      360

gctaaaggtt gcttttctct gcaccgtccg ttcttgctcc ctctgctcca tcactgggac      420

cttgtcaggc gttcataaag caaaatttgc cgaacgaggg ttcgcagaaa ggtggggcag      480

agctcatctg acgtggcatc agtgtgaaag aaaatgtctt tatttaaagc ccgtgattgg      540

tggtctacta ttctgggaga taaagaagaa tttgatcaag gctgtttgtg tctggctaat      600

gttgacaata gtggaaatgg acaagataaa ataattgtgg gtagctttat gggataccta      660

aggatcttta gcccccatcc tgcaaaaaca ggagatggag ctcaagccga agatttgctt      720

ctagaagtgg atctacgaga tccagtactt caagtggaag taggaaagtt tgtttcaggt      780

accgaaatgc tacatttggc tgtgttacat tctagaaaac tttgtgtcta ctctgtctca      840

ggaaccttgg gtaatgtgga acatgggaac caatgtcaga tgaaattgat gtatgaacat      900

aatcttcaga gaacagcctg caatatgacc tatggatcat ttggtggtgt aaaaggtcga      960

gatttaattt gcatccagtc tatggatggg atgctgatgg tatttgagca ggagagctat     1020

gcttttggaa gatttctccc tggctttctt ctgcctggtc ctcttgccta cagttcccgt     1080

acagattcct tccttactgt ctcttcctgc caacaagtgg aaagttataa gtaccaggta     1140

cttgcttttg caacagatgc agataaaagg caggagactg aacagcaaaa acttggttct     1200

ggaaaaagac tagttgtgga ttggactcta aatattggag agcaagccct tgacatatgt     1260

attgtctctt tcaatcagtc ggcatcctct gtttttgttc ttggtgagag aaactttttt     1320

tgccttaagg ataatggaca aattcgattc atgaagaagc ttgattggag cccaagttgt     1380

tttctgccat attgctcagt ttctgaagga acaataaata ctttgattgg aaatcataat     1440

aacatgctgc atatttatca agatgtgaca ctgaagtggg ccacccaact tccccacatt     1500

cctgtagcag taagagtggg ctgtttgcat gatttaaagg gagtgatagt cactctgagt     1560

gatgatggtc acttgcagtg ttcatacctg gggacagatc cttctctgtt ccaagctcca     1620

aacgttcaat ctcgagaact aaactatgat gaacttgatg tagaaatgaa agaacttcag     1680

aaaatcatca aagatgttaa caaatcacaa ggtgtttggc ccatgactga gagagaagat     1740

gacttgaacg tttctgtcgt ggtttctcct aactttgatt cagtttctca agcgaccgat     1800

gttgaggtgg gaactgacct tgtcccttct gtcacggtga aggtcacact gcagaacaga     1860

gtgatattgc aaaaagccaa attatcagtc tacgtgcaac caccattaga attgacttgt     1920

gatcagttca cctttgaatt tatgacacca gatttgacta gaacagtaag cttttctgtt     1980

tatctgaaaa gaagttatac accatcagaa ttggaaggaa atgctgttgt ttcttattcc     2040

agaccaacag atcgaaatcc tgatggcatt ccgcgagtta tccaatgtaa atttagactt     2100

cccctaaagt taatttgcct accaggtcag ccttcaaaaa ctgcaagcca caaaattact     2160

attgatacca acaaatctcc agtcagtctt cttagtctct tcccaggttt tgccagtcag     2220

tcagatgatg atcaggtgaa tgtaatgggt tttcacttct taggaggtgc tcgaattact     2280

gttcttgctt ccaaaacttc tcaacgatat cgcattcaga gtgaacaatt tgaagatctt     2340

tggctcataa ccaatgagct tattcttcgc cttcaagaat attttgaaaa acagggagtc     2400

aaagattttg catgttcttt ttcgggatct ataccccttc aagaatattt tgagttgatt     2460

gatcatcatt ttgagctacg gataaatggt gaaaaattag aagaactctt atctgagaga     2520

gctgtacaat ttcgggccat tcaacgccgg ctactagcaa gattcaaaga taaaactcct     2580

gcccctcttc aacacctgga caccttgtta gatggaacct acaagcaggt aattgctcta     2640

gcagatgcag tggaggaaaa ccaaggcaat ctgttccagt cattcaccag gctgaagagt     2700

gccacccatt tggtgattct gctgatcgcg ctgtggcaga agcttagtgc tgaccaggtt     2760

gctattctgg aagcggcatt tctgccgcta caagaagaca ctcaagaatt gggctgggaa     2820

gaaacggtgg atgccgccat ttcccacctg ttgaagactt gcctgtcgaa gagttctaag     2880

gagcaggctt tgaacctcaa cagccagctg aacataccca aagacacaag ccaactgaag     2940

aaacatatca ccttgctctg cgatagatta tccaaaggtg gccgtctctg cctaagtacc     3000

gatgcagcag ccccacagac catggtcatg ccaggtggtt gtactacaat cccagagtca     3060

gacctagaag aaagatcagt agaacaagac tctacagaac tgtttaccaa ccacagacat     3120

ctcactgcag agacacccag gcctgaagtt tcacccctcc aaggagtctc ggaataattc     3180

aagtagagtt gtttggttga gaggaacatc cccatctcaa ggccgaacct gtgtgaacct     3240

catgccaagc acagatatag ggctggcgca ggtgcttcct aaagctcacc ttcctggaga     3300

tgacatgcat agaaagaggg gttgggactt tttacttcac taggagaact tgtaacacca     3360

tggggaagtc agctgaaact tgtcttgttt tgccaggaaa ggaagtagtt gcctttggtc     3420

atccatctgc taatagtcac agaatacagt gaaatgacat agttttgggt tagattttat     3480

aatgcaaaga ttcagatcca aaataatttc ataccccatt ttttcacaga attcttatat     3540

agtaaatgta tcaagtttaa taaagcatct cattgtcaaa taatatcttg gattttattt     3600

ataattagag ggatttatga gtgattgctc tacattattt cttcaaagga aaggaaagga     3660

attgaagact ttgctactct ctggtaagac ttgaatgtga ttattttata aataaaagaa     3720

ccactatgaa actttcatgt gatttgttct attaagctaa acgtggaaga agggaagttt     3780

tctagtattg tatgaaaatg tttaaatatt ttcaaggaag ctagtacatt aacatcccct     3840

tttcattacc ccattgggtg gcacctttta aaaatccagg ttattaaagg attcacactt     3900

tattacagtt aaaatttaag gtttttatgt gtaagaagtg aaagaaactt tgctaatttc     3960

aagttcgaat tacagttgtg agattgattt atttaaataa aaatatgcct ttgccagtt      4019


<210>  1402
<211>  4206
<212>  DNA
<213>  homo sapiens

<400>  1402
ataactttgt agcgagtcga aaactgaggc tccggccgca gagaactcag cctcattcct       60

gctttaaaat ctctcggcca cctttgatga ggggactggg cagttctaga cagtcccgaa      120

gttctcaagg cacaggtctc ttcctggttt gactgtcctt accccgggga ggcagtgcag      180

ccagctgcaa gccccacagt gaagaacatc tgagctcaaa tccagataag tgacataagt      240

gacctgcttt gtaaagccat agagatggcc tgtccttgga aatttctgtt caagaccaaa      300

ttccaccagt atgcaatgaa tggggaaaaa gacatcaaca acaatgtgga gaaagccccc      360

tgtgccacct ccagtccagt gacacaggat gaccttcagt atcacaacct cagcaagcag      420

cagaatgagt ccccgcagcc cctcgtggag acgggaaaga agtctccaga atctctggtc      480

aagctggatg caaccccatt gtcctcccca cggcatgtga ggatcaaaaa ctggggcagc      540

gggatgactt tccaagacac acttcaccat aaggccaaag ggattttaac ttgcaggtcc      600

aaatcttgcc tggggtccat tatgactccc aaaagtttga ccagaggacc cagggacaag      660

cctacccctc cagatgagct tctacctcaa gctatcgaat ttgtcaacca atattacggc      720

tccttcaaag aggcaaaaat agaggaacat ctggccaggg tggaagcggt aacaaaggag      780

atagaaacaa caggaaccta ccaactgacg ggagatgagc tcatcttcgc caccaagcag      840

gcctggcgca atgccccacg ctgcattggg aggatccagt ggtccaacct gcaggtcttc      900

gatgcccgca gctgttccac tgcccgggaa atgtttgaac acatctgcag acacgtgcgt      960

tactccacca acaatggcaa catcaggtcg gccatcaccg tgttccccca gcggagtgat     1020

ggcaagcacg acttccgggt gtggaatgct cagctcatcc gctatgctgg ctaccagatg     1080

ccagatggca gcatcagagg ggaccctgcc aacgtggaat tcactcagct gtgcatcgac     1140

ctgggctgga agcccaagta cggccgcttc gatgtggtcc ccctggtcct gcaggccaat     1200

ggccgtgacc ctgagctctt cgaaatccca cctgaccttg tgcttgaggt ggccatggaa     1260

catcccaaat acgagtggtt tcgggaactg gagctaaagt ggtacgccct gcctgcagtg     1320

gccaacatgc tgcttgaggt gggcggcctg gagttcccag ggtgcccctt caatggctgg     1380

tacatgggca cagagatcgg agtccgggac ttctgtgacg tccagcgcta caacatcctg     1440

gaggaagtgg gcaggagaat gggcctggaa acgcacaagc tggcctcgct ctggaaagac     1500

caggctgtcg ttgagatcaa cattgctgtg ctccatagtt tccagaagca gaatgtgacc     1560

atcatggacc accactcggc tgcagaatcc ttcatgaagt acatgcagaa tgaataccgg     1620

tcccgtgggg gctgcccggc agactggatt tggctggtcc ctcccatgtc tgggagcatc     1680

acccccgtgt ttcaccagga gatgctgaac tacgtcctgt cccctttcta ctactatcag     1740

gtagaggcct ggaaaaccca tgtctggcag gacgagaagc ggagacccaa gagaagagag     1800

attccattga aagtcttggt caaagctgtg ctctttgcct gtatgctgat gcgcaagaca     1860

atggcgtccc gagtcagagt caccatcctc tttgcgacag agacaggaaa atcagaggcg     1920

ctggcctggg acctgggggc cttattcagc tgtgccttca accccaaggt tgtctgcatg     1980

gataagtaca ggctgagctg cctggaggag gaacggctgc tgttggtggt gaccagtacg     2040

tttggcaatg gagactgccc tggcaatgga gagaaactga agaaatcgct cttcatgctg     2100

aaagagctca acaacaaatt caggtacgct gtgtttggcc tcggctccag catgtaccct     2160

cggttctgcg cctttgctca tgacattgat cagaagctgt cccacctggg ggcctctcag     2220

ctcaccccga tgggagaagg ggatgagctc agtgggcagg aggacgcctt ccgcagctgg     2280

gccgtgcaaa ccttcaaggc agcctgtgag acgtttgatg tccgaggcaa acagcacatt     2340

cagatcccca agctctacac ctccaatgtg acctgggacc cgcaccacta caggctcgtg     2400

caggactcac agcctttgga cctcagcaaa gccctcagca gcatgcatgc caagaacgtg     2460

ttcaccatga ggctcaaatc tcggcagaat ctacaaagtc cgacatccag ccgtgccacc     2520

atcctggtgg aactctcctg tgaggatggc caaggcctga actacctgcc gggggagcac     2580

cttggggttt gcccaggcaa ccagccggcc ctggtccaag gtatcctgga gcgagtggtg     2640

gatggcccca caccccacca gacagtgcgc ctggaggccc tggatgagag tggcagctac     2700

tgggtcagtg acaagaggct gcccccctgc tcactcagcc aggccctcac ctacttcctg     2760

gacatcacca cacccccaac ccagctgctg ctccaaaagc tggcccaggt ggccacagaa     2820

gagcctgaga gacagaggct ggaggccctg tgccagccct cagagtacag caagtggaag     2880

ttcaccaaca gccccacatt cctggaggtg ctagaggagt tcccgtccct gcgggtgtct     2940

gctggcttcc tgctttccca gctccccatt ctgaagccca ggttctactc catcagctcc     3000

tcccgggatc acacgcccac agagatccac ctgactgtgg ccgtggtcac ctaccacacc     3060

cgagatggcc agggtcccct gcaccacggc gtctgcagca catggctcaa cagcctgaag     3120

ccccaagacc cagtgccctg ctttgtgcgg aatgccagcg gcttccacct ccccgaggat     3180

ccctcccatc cttgcatcct catcgggcct ggcacaggca tcgcgccctt ccgcagtttc     3240

tggcagcaac ggctccatga ctcccagcac aagggagtgc ggggaggccg catgaccttg     3300

gtgtttgggt gccgccgccc agatgaggac cacatctacc aggaggagat gctggagatg     3360

gcccagaagg gggtgctgca tgcggtgcac acagcctatt cccgcctgcc tggcaagccc     3420

aaggtctatg ttcaggacat cctgcggcag cagctggcca gcgaggtgct ccgtgtgctc     3480

cacaaggagc caggccacct ctatgtttgc ggggatgtgc gcatggcccg ggacgtggcc     3540

cacaccctga agcagctggt ggctgccaag ctgaaattga atgaggagca ggtcgaggac     3600

tatttctttc agctcaagag ccagaagcgc tatcacgaag atatctttgg tgctgtattt     3660

ccttacgagg cgaagaagga cagggtggcg gtgcagccca gcagcctgga gatgtcagcg     3720

ctctgagggc ctacaggagg ggttaaagct gccggcacag aacttaagga tggagccagc     3780

tctgcattat ctgaggtcac agggcctggg gagatggagg aaagtgatat cccccagcct     3840

caagtcttat ttcctcaacg ttgctcccca tcaagccctt tacttgacct cctaacaagt     3900

agcaccctgg attgatcgga gcctcctctc tcaaactggg gcctccctgg tcccttggag     3960

acaaaatctt aaatgccagg cctggcaagt gggtgaaaga tggaacttgc tgctgagtgc     4020

accacttcaa gtgaccacca ggaggtgcta tcgcaccact gtgtatttaa ctgccttgtg     4080

tacagttatt tatgcctctg tatttaaaaa actaacaccc agtctgttcc ccatggccac     4140

ttgggtcttc cctgtatgat tccttgatgg agatatttac atgaattgca ttttacttta     4200

atcaca                                                                4206


<210>  1403
<211>  2707
<212>  DNA
<213>  homo sapiens

<400>  1403
gagcggtcac gtgtgagggg cggcccgagg tcacgtgacg gagcgccgga gcggagggag       60

ccggggctgg gagttctcct gagggaagag gagtggagta ggggggacgc ggcggcggcg      120

ttgacaatga gttttcttgg aggctttttt ggtccaattt gtgagatcga tattgttctt      180

aatgatgggg aaaccaggaa aatggcagaa atgaaaactg aagatggcaa agtagaaaaa      240

cactatctct tctatgacgg agaatccgtt tcaggaaagg taaacctagc ctttaagcaa      300

cctggaaaga ggctagaaca ccaaggaatt agaattgaat ttgtaggtca aattgaactt      360

ttcaatgaca agagtaatac tcatgaattt gtaaacctag tgaaagaact agccttacct      420

ggagaactga ctcagagcag aagttatgat tttgaattta tgcaagttga aaagccatat      480

gaatcttaca tcggtgccaa tgtccgcttg aggtattttc ttaaagtgac aatagtgaga      540

agactgacag atttggtaaa agagtatgat cttattgttc accagcttgc cacctatcct      600

gatgttaaca actctattaa gatggaagtg ggcattgaag attgtctaca tatagaattt      660

gaatataata aatcaaagta tcatttaaag gatgtgattg ttggaaaaat ttacttctta      720

ttagtaagaa taaaaataca acatatggag ttacagctga tcaaaaaaga gatcacagga      780

attggaccca gtaccacaac agaaacagaa acaatcgcca aatatgaaat aatggatggt      840

gcaccagtaa aaggtgaatc aattccaata aggctatttt tagcaggata tgacccaact      900

ccaacaatga gagatgtgaa caaaaaattt tcagtaaggt actttttgaa tttagtgctt      960

gttgatgagg aagaccggag gtacttcaaa cagcaggaga taattttatg gagaaaagct     1020

cctgaaaaac tgaggaaaca gagaacaaac tttcaccagc gatttgaatc tccagaatca     1080

caggcatctg ccgaacagcc tgaaatgtga actgaacagg agaaaaaaag aaaagcaaaa     1140

aactcctgta acccttgaga ttaagttcag caggttaaag atggttgcag ctggaggggg     1200

cggaaaaagg ccaaaactcc atatatgtta gtcttccttt atcttacagc gcagcattta     1260

ttttatgata taatgaaatg ttcgttcatg tatatacatt tttaaaagtg ctttctttga     1320

aacactggaa ctttgttaag ctgccttttt ttttttaact tcctactttg atgataagca     1380

ctcagatata tatcagcgta aacatgaaaa attttcatgt gagtaggctg gtatttgtaa     1440

ttttgctttc tttctgcata atgttgatta taaatcctct cttttcaggc taatgattac     1500

ctcttattct ctacatgcaa aaaattaaat attttgtgtt caaataaaat tagaaaacct     1560

gagtggcctc ttgtgtcctg cagagattta aaacatggca tctcaatatt tttgagaact     1620

acatttgttt ttaacatatg tgtttgagaa aagcatatgg agtgtttcac cgcaggcact     1680

tctgagtacc attccatggc ttccagaatt ttatcctctt tgaggtcttc tgtgctatga     1740

atattagatt tctttcccca agggattatg tggcaggtca ttatggcctt cttttttttg     1800

gccatattaa gtaacagttt tgctatattc cagtagtacc gttgtgtgtt ttctgcaatg     1860

tggagttgac ttagcttggc attttagatt tgttaaaact attttttcca taaatacttt     1920

gaaacatatt tatatatttc aatttaagga atctttttgc catgtgtatg caaatattat     1980

tttcttcata cattcatttt cttttcaggg gaaaattttg ggatggggga ctcaggagga     2040

cctgtgaagc atgtagttat ctagatctgg gtaatttcat gtttattaaa ctcgaacttt     2100

ggctagttaa actcatattg aaacttcatc tagtctctta attttttaac actaaattca     2160

agtcatttgt tttaagtctc taaaaaagaa gattgcagtc atccattcat atgcatgggg     2220

tctgatcgca aatacactaa atgtggagtg taggaaccaa aatgaaacct gctgtatgga     2280

aactactttc acttatggtt cattggtttt tgtaccaata ttttttatgc acttcagtgc     2340

aagtcttgtc agttaacctt actttatgag taagctaaat aacccaaatt acatttcttt     2400

aaacctgttt tactactatg gcactttgat aaaatggtca ggaaccaact ttactggcaa     2460

aagggtccat gtaccaccat gtgctggagc atctgttcta catgtggata tctatgaatg     2520

gtaatgtttt ccttcatgta agtgcctatt cagagtttca gaattttaaa atgccaaata     2580

ttttcatggt catttgcatg tagtaagcca gaaaatattc aaagagattt tgaaaaccaa     2640

ttgtatttaa ccagcctcaa attgtgcaac catgatgtat aataaagaat ttgaaacaga     2700

aaaaaaa                                                               2707


<210>  1404
<211>  684
<212>  DNA
<213>  homo sapiens

<400>  1404
aggcgagggg gcggagcaag agaagaaaac acaaagggcc ggaaggaagc cggggagaca       60

ggtggggtac tcgggaagct ggagcgggcc ggcggtgcag tcacggggga gcgaggcctg      120

ctgggcttgg caacgaggga ctcggcctcg gaggcgaccc agaccacaca gacactgggt      180

caaggagtaa gcagaggata aacaactgga aggagagcaa gcacaaagtc atcatggctt      240

cagcgtctgc tcgtggaaac caagataaag atgcccattt tccaccacca agcaagcaga      300

gcctgttgtt ttgtccaaaa tcaaaactgc acatccacag agcagagatc tcaaagatta      360

tgcgagaatg tcaggaagaa agtttctgga agagagctct gcctttttct cttgtaagca      420

tgcttgtcac ccagggacta gtctaccaag gttatttggc agctaattct agatttggat      480

cattgcccaa agttgcacgc actgcctcct tacctgtgag gaatgcaaaa taaagcatgg      540

attaagtgag aagggagact ctcagccttc agcttcctaa attctgtgtc tgtgactttc      600

gaagtttttt aaacctctga atttgtacac atttaaaatt tcaagtgtac tttaaaataa      660

aatacttcta atggaacaaa aaca                                             684


<210>  1405
<211>  684
<212>  DNA
<213>  homo sapiens

<400>  1405
aggcgagggg gcggagcaag agaagaaaac acaaagggcc ggaaggaagc cggggagaca       60

ggtggggtac tcgggaagct ggagcgggcc ggcggtgcag tcacggggga gcgaggcctg      120

ctgggcttgg caacgaggga ctcggcctcg gaggcgaccc agaccacaca gacactgggt      180

caaggagtaa gcagaggata aacaactgga aggagagcaa gcacaaagtc atcatggctt      240

cagcgtctgc tcgtggaaac caagataaag atgcccattt tccaccacca agcaagcaga      300

gcctgttgtt ttgtccaaaa tcaaaactgc acatccacag agcagagatc tcaaagatta      360

tgcgagaatg tcaggaagaa agtttctgga agagagctct gcctttttct cttgtaagca      420

tgcttgtcac ccagggacta gtctaccaag gttatttggc agctaattct agatttggat      480

cattgcccaa agttgcacgc actgcctcct tacctgtgag gaatgcaaaa taaagcatgg      540

attaagtgag aagggagact ctcagccttc agcttcctaa attctgtgtc tgtgactttc      600

gaagtttttt aaacctctga atttgtacac atttaaaatt tcaagtgtac tttaaaataa      660

aatacttcta atggaacaaa aaca                                             684


<210>  1406
<211>  5497
<212>  DNA
<213>  homo sapiens

<400>  1406
agttccggcc catgttgttt cggccgagga gccgtcgccg ccatttcaag accgtactag       60

gtagatggtc aattagagtt cccagggttt gaagcctgta actgctgccg ccgctcaagc      120

cctccagagc attgctacgg ctgctgccct tgtactacta cctccaaata cgttcttgct      180

ggtagtggcg gcagcaggac caattacctc ttttttgctc tccctcgaga agctccagat      240

ggcgtcttcc gtgggcaacg tggccgacag cacagaacca acgaaacgta tgctttcctt      300

ccaagggtta gctgagttgg cacatcgaga atatcaggca ggagattttg aggcagctga      360

gagacactgc atgcagctct ggagacaaga gccagacaat actggtgtgc ttttattact      420

ttcatctata cacttccagt gtcgaaggct ggacagatct gctcacttta gcactctggc      480

aattaaacag aacccccttc tggcagaagc ttattcgaat ttggggaatg tgtacaagga      540

aagagggcag ttgcaggagg caattgagca ttatcgacat gcattgcgtc tcaaacctga      600

tttcatcgat ggttatatta acctggcagc cgccttggta gcagcgggtg acatggaagg      660

ggcagtacaa gcttacgtct ctgctcttca gtacaatcct gatttgtact gtgttcgcag      720

tgacctgggg aacctgctca aagccctggg tcgcttggaa gaagccaagg catgttattt      780

gaaagcaatt gagacgcaac cgaactttgc agtagcttgg agtaatcttg gctgtgtttt      840

caatgcacaa ggggaaattt ggcttgcaat tcatcacttt gaaaaggctg tcacccttga      900

cccaaacttt ctggatgctt atatcaattt aggaaatgtc ttgaaagagg cacgcatttt      960

tgacagagct gtggcagctt atcttcgtgc cctaagtttg agtccaaatc acgcagtggt     1020

gcacggcaac ctggcttgtg tatactatga gcaaggcctg atagatctgg caatagacac     1080

ctacaggcgg gctatcgaac tacaaccaca tttccctgat gcttactgca acctagccaa     1140

tgctctcaaa gagaagggca gtgttgctga agcagaagat tgttataata cagctctccg     1200

tctgtgtccc acccatgcag actctctgaa taacctagcc aatatcaaac gagaacaggg     1260

aaacattgaa gaggcagttc gcttgtatcg taaagcatta gaagtcttcc cagagtttgc     1320

tgctgcccat tcaaatttag caagtgtact gcagcagcag ggaaaactgc aggaagctct     1380

gatgcattat aaggaggcta ttcgaatcag tcctaccttt gctgatgcct actctaatat     1440

gggaaacact ctaaaggaga tgcaggatgt tcagggagcc ttgcagtgtt atacgcgtgc     1500

catccaaatt aatcctgcat ttgcagatgc acatagcaat ctggcttcca ttcataagga     1560

ttcagggaat attccagaag ccatagcttc ttaccgcacg gctctgaaac ttaagcctga     1620

ttttcctgat gcttattgta acttggctca ttgcctgcag attgtctgtg attggacaga     1680

ctatgatgag cgaatgaaga agttggtcag tattgtggct gaccagttag agaagaatag     1740

gttgccttct gtgcatcctc atcatagtat gctatatcct ctttctcatg gcttcaggaa     1800

ggctattgct gagaggcacg gcaacctgtg cttagataag attaatgttc ttcataaacc     1860

accatatgaa catccaaaag acttgaagct cagtgatggt cggctgcgtg taggatatgt     1920

gagttccgac tttgggaatc atcctacttc tcaccttatg cagtctattc caggcatgca     1980

caatcctgat aaatttgagg tgttctgtta tgccctgagc ccagacgatg gcacaaactt     2040

ccgagtgaag gtgatggcag aagccaatca tttcattgat ctttctcaga ttccatgcaa     2100

tggaaaagca gctgatcgca tccatcagga tggaattcat atccttgtaa atatgaatgg     2160

ctatactaag ggcgctcgaa atgagctttt tgctctcagg ccagctccta ttcaggcaat     2220

gtggctggga taccctggga cgagtggtgc gcttttcatg gattatatta tcactgatca     2280

ggaaacttcg ccagctgaag ttgctgagca gtattccgag aaattggctt atatgcccca     2340

cacttttttt attggtgatc atgctaatat gttccctcac ctgaagaaaa aagcagtcat     2400

cgattttaag tccaatgggc acatttatga caatcggata gttctgaatg gcatcgacct     2460

caaagcattt cttgatagtc taccagatgt gaaaattgtc aagatgaagt gtcctgatgg     2520

aggagacaat gcagatagca gtaacacagc tcttaatatg cctgttattc ctatgaatac     2580

tattgcagaa gcagttattg aaatgattaa ccgaggacag attcaaataa caattaatgg     2640

attcagtatt agcaatggac tggcaactac tcagatcaac aataaggctg caactggaga     2700

ggaggttccc cgtaccatta ttgtaaccac ccgttctcag tacgggttac cagaagatgc     2760

catcgtatac tgtaacttta atcagttgta taaaattgac ccttctactt tgcagatgtg     2820

ggcaaacatt ctgaagcgtg ttcccaatag tgtactctgg ctgttgcgtt ttccagcagt     2880

aggagaacct aatattcaac agtatgcaca aaacatgggc ctgccccaga accgtatcat     2940

tttttcacct gttgctccta aagaggaaca cgtcaggaga ggccagctgg ctgatgtctg     3000

cttggacact ccactctgta atgggcacac cacagggatg gatgtcctct gggcagggac     3060

ccccatggtg actatgccag gagagactct tgcttctcga gttgcagcat cccagctcac     3120

ttgcttaggt tgtcttgagc ttattgctaa aaacagacaa gaatatgaag acatagctgt     3180

gaagctggga actgatctag aatacctgaa gaaagttcgt ggcaaagtct ggaagcaaag     3240

aatatctagc cctctgttca acaccaaaca atacacaatg gaactagagc ggctctatct     3300

acagatgtgg gagcattatg cagctggcaa caaacctgac cacatgatta agcctgttga     3360

agtcactgag tcagcataaa taaagactgc acaggagaat tacccctata cctgagcctc     3420

aaccttctgg gggaaaggga actagataac atacttctta cttgtctgta cagtaccttg     3480

ttgcagatgg gtgatatata atggtaatag aatagcacag ccagacttgc ttcctgcatg     3540

gtagggagag acacaaaaga tgggaaactg cttttccaca aggaatctcc gtagaatttt     3600

gcggcgacca gatggtgcat aggtctggaa ggtctgatct cccttggtct tccatgggat     3660

ggttagtgtg gaggggagat atagattgtc cggccgcttt gtgattccat ggattgattc     3720

agtcttctgg attttttttt ctttatattt tgggtactgg agcttttaaa aatgtttggt     3780

ttcaggtatt tttattcatg tgaagtgtat atgattctct tgagataagg ttttaagcta     3840

aaatgttact ccctgtttta gtttctgaac tctgacagat tgacagggac tttgctggtg     3900

tagtcttttt ataggtttta taaaccactt gagcctatat cagtcgtttt agtgtctgac     3960

ctaatatttg gagctatcag tgctttgttg atttagatga tgactcaaga ttttttctgg     4020

tccatttccc atttcctttt cttccctgac ccccataccc tcacccttaa aattctcctg     4080

taactcaact aacaaaatca agcctgattc aaaacatcct agggtgtttt aaacacacca     4140

tctggtgcca aatgaagatt tttaggagtg attactaatt atcaagggca cagttgtggt     4200

actgtcattg ataataatat agtttttttt tttttcctaa ttttgacctg tttcaccagt     4260

gttttaccct tgactgcccc ttctatgctg cttccaaaag tgatagtgtg tgtaagattt     4320

ttaccttcct ttctaaagtt tttttttttt ttttttaagt gagtcctgtt cttcctattt     4380

ctttcagcag aaatgaaatc ccaggtaagt ataagtattc aagtatttga tcagtaagtc     4440

acagttatct ccagtgcatt aaataacctt catcaagaaa taggttatag gtaaaatctc     4500

tgaaggatca tctatgtatt caagtaatta ttttttagat aataactgtc ttctggactt     4560

ggtcttgaag tctgtacaga ttcagcctca gtagtagcga actgcactgc tgtttggttt     4620

ggagtacaaa ttagacttat agtcctcctg gaacttgagt tattaaaatc ataggaataa     4680

aattatggga tctcaacaaa gggtcgaggg tttgaggctt aaacaagcca acatatgaat     4740

atatgttttg tctcgctata ctgcacttac gctatccagt tgcaggtaat tttttgtctg     4800

ctagtagtgt tctagattat gtctttccaa agcgctgagg ctgtgcacct attctgtagt     4860

tgcagctgat gcctgaatgt atcctagctg acaaattatt gattaataag aacttgaatt     4920

tctggaagat tcttactgtt aaccaaattt tgagcaagga gtctcaaagg taattctgaa     4980

ccagaattac atgttaatga acagtgtacc ttttaacagt gtaaatcacg gaatatccgt     5040

gaagggattt cttaatttat tttttaccgg ttgattgaaa tatcagttaa aggttgccag     5100

catggttgca gataaactga tgtttgaaat tcgctgaaat acttaatgtg gaataggata     5160

atatacttcc aatgccctca aggctgtgac cttacagcca ttttacatag cacatcattc     5220

ctcctatagg gatgaacttt ttcctggcac gaaaagtagc cgctctggtt gaagctttgc     5280

ttattgtaac aggcttttat ttccaggtaa tatgtcttgg aagacttaat tctgattaga     5340

gatatagata ttactggaaa ctaattgttt tttttctatt gtactctgct ttatcaaaga     5400

agtaaaacat ttaaatcgta ctacagaaat taagatgttg tcttgcgatc cttaataaat     5460

gaatgatttc cctttaatac ggaaaaaaaa aaaaaaa                              5497


<210>  1407
<211>  5467
<212>  DNA
<213>  homo sapiens

<400>  1407
agttccggcc catgttgttt cggccgagga gccgtcgccg ccatttcaag accgtactag       60

gtagatggtc aattagagtt cccagggttt gaagcctgta actgctgccg ccgctcaagc      120

cctccagagc attgctacgg ctgctgccct tgtactacta cctccaaata cgttcttgct      180

ggtagtggcg gcagcaggac caattacctc ttttttgctc tccctcgaga agctccagat      240

ggcgtcttcc gtgggcaacg tggccgacag cacagggtta gctgagttgg cacatcgaga      300

atatcaggca ggagattttg aggcagctga gagacactgc atgcagctct ggagacaaga      360

gccagacaat actggtgtgc ttttattact ttcatctata cacttccagt gtcgaaggct      420

ggacagatct gctcacttta gcactctggc aattaaacag aacccccttc tggcagaagc      480

ttattcgaat ttggggaatg tgtacaagga aagagggcag ttgcaggagg caattgagca      540

ttatcgacat gcattgcgtc tcaaacctga tttcatcgat ggttatatta acctggcagc      600

cgccttggta gcagcgggtg acatggaagg ggcagtacaa gcttacgtct ctgctcttca      660

gtacaatcct gatttgtact gtgttcgcag tgacctgggg aacctgctca aagccctggg      720

tcgcttggaa gaagccaagg catgttattt gaaagcaatt gagacgcaac cgaactttgc      780

agtagcttgg agtaatcttg gctgtgtttt caatgcacaa ggggaaattt ggcttgcaat      840

tcatcacttt gaaaaggctg tcacccttga cccaaacttt ctggatgctt atatcaattt      900

aggaaatgtc ttgaaagagg cacgcatttt tgacagagct gtggcagctt atcttcgtgc      960

cctaagtttg agtccaaatc acgcagtggt gcacggcaac ctggcttgtg tatactatga     1020

gcaaggcctg atagatctgg caatagacac ctacaggcgg gctatcgaac tacaaccaca     1080

tttccctgat gcttactgca acctagccaa tgctctcaaa gagaagggca gtgttgctga     1140

agcagaagat tgttataata cagctctccg tctgtgtccc acccatgcag actctctgaa     1200

taacctagcc aatatcaaac gagaacaggg aaacattgaa gaggcagttc gcttgtatcg     1260

taaagcatta gaagtcttcc cagagtttgc tgctgcccat tcaaatttag caagtgtact     1320

gcagcagcag ggaaaactgc aggaagctct gatgcattat aaggaggcta ttcgaatcag     1380

tcctaccttt gctgatgcct actctaatat gggaaacact ctaaaggaga tgcaggatgt     1440

tcagggagcc ttgcagtgtt atacgcgtgc catccaaatt aatcctgcat ttgcagatgc     1500

acatagcaat ctggcttcca ttcataagga ttcagggaat attccagaag ccatagcttc     1560

ttaccgcacg gctctgaaac ttaagcctga ttttcctgat gcttattgta acttggctca     1620

ttgcctgcag attgtctgtg attggacaga ctatgatgag cgaatgaaga agttggtcag     1680

tattgtggct gaccagttag agaagaatag gttgccttct gtgcatcctc atcatagtat     1740

gctatatcct ctttctcatg gcttcaggaa ggctattgct gagaggcacg gcaacctgtg     1800

cttagataag attaatgttc ttcataaacc accatatgaa catccaaaag acttgaagct     1860

cagtgatggt cggctgcgtg taggatatgt gagttccgac tttgggaatc atcctacttc     1920

tcaccttatg cagtctattc caggcatgca caatcctgat aaatttgagg tgttctgtta     1980

tgccctgagc ccagacgatg gcacaaactt ccgagtgaag gtgatggcag aagccaatca     2040

tttcattgat ctttctcaga ttccatgcaa tggaaaagca gctgatcgca tccatcagga     2100

tggaattcat atccttgtaa atatgaatgg ctatactaag ggcgctcgaa atgagctttt     2160

tgctctcagg ccagctccta ttcaggcaat gtggctggga taccctggga cgagtggtgc     2220

gcttttcatg gattatatta tcactgatca ggaaacttcg ccagctgaag ttgctgagca     2280

gtattccgag aaattggctt atatgcccca cacttttttt attggtgatc atgctaatat     2340

gttccctcac ctgaagaaaa aagcagtcat cgattttaag tccaatgggc acatttatga     2400

caatcggata gttctgaatg gcatcgacct caaagcattt cttgatagtc taccagatgt     2460

gaaaattgtc aagatgaagt gtcctgatgg aggagacaat gcagatagca gtaacacagc     2520

tcttaatatg cctgttattc ctatgaatac tattgcagaa gcagttattg aaatgattaa     2580

ccgaggacag attcaaataa caattaatgg attcagtatt agcaatggac tggcaactac     2640

tcagatcaac aataaggctg caactggaga ggaggttccc cgtaccatta ttgtaaccac     2700

ccgttctcag tacgggttac cagaagatgc catcgtatac tgtaacttta atcagttgta     2760

taaaattgac ccttctactt tgcagatgtg ggcaaacatt ctgaagcgtg ttcccaatag     2820

tgtactctgg ctgttgcgtt ttccagcagt aggagaacct aatattcaac agtatgcaca     2880

aaacatgggc ctgccccaga accgtatcat tttttcacct gttgctccta aagaggaaca     2940

cgtcaggaga ggccagctgg ctgatgtctg cttggacact ccactctgta atgggcacac     3000

cacagggatg gatgtcctct gggcagggac ccccatggtg actatgccag gagagactct     3060

tgcttctcga gttgcagcat cccagctcac ttgcttaggt tgtcttgagc ttattgctaa     3120

aaacagacaa gaatatgaag acatagctgt gaagctggga actgatctag aatacctgaa     3180

gaaagttcgt ggcaaagtct ggaagcaaag aatatctagc cctctgttca acaccaaaca     3240

atacacaatg gaactagagc ggctctatct acagatgtgg gagcattatg cagctggcaa     3300

caaacctgac cacatgatta agcctgttga agtcactgag tcagcataaa taaagactgc     3360

acaggagaat tacccctata cctgagcctc aaccttctgg gggaaaggga actagataac     3420

atacttctta cttgtctgta cagtaccttg ttgcagatgg gtgatatata atggtaatag     3480

aatagcacag ccagacttgc ttcctgcatg gtagggagag acacaaaaga tgggaaactg     3540

cttttccaca aggaatctcc gtagaatttt gcggcgacca gatggtgcat aggtctggaa     3600

ggtctgatct cccttggtct tccatgggat ggttagtgtg gaggggagat atagattgtc     3660

cggccgcttt gtgattccat ggattgattc agtcttctgg attttttttt ctttatattt     3720

tgggtactgg agcttttaaa aatgtttggt ttcaggtatt tttattcatg tgaagtgtat     3780

atgattctct tgagataagg ttttaagcta aaatgttact ccctgtttta gtttctgaac     3840

tctgacagat tgacagggac tttgctggtg tagtcttttt ataggtttta taaaccactt     3900

gagcctatat cagtcgtttt agtgtctgac ctaatatttg gagctatcag tgctttgttg     3960

atttagatga tgactcaaga ttttttctgg tccatttccc atttcctttt cttccctgac     4020

ccccataccc tcacccttaa aattctcctg taactcaact aacaaaatca agcctgattc     4080

aaaacatcct agggtgtttt aaacacacca tctggtgcca aatgaagatt tttaggagtg     4140

attactaatt atcaagggca cagttgtggt actgtcattg ataataatat agtttttttt     4200

tttttcctaa ttttgacctg tttcaccagt gttttaccct tgactgcccc ttctatgctg     4260

cttccaaaag tgatagtgtg tgtaagattt ttaccttcct ttctaaagtt tttttttttt     4320

ttttttaagt gagtcctgtt cttcctattt ctttcagcag aaatgaaatc ccaggtaagt     4380

ataagtattc aagtatttga tcagtaagtc acagttatct ccagtgcatt aaataacctt     4440

catcaagaaa taggttatag gtaaaatctc tgaaggatca tctatgtatt caagtaatta     4500

ttttttagat aataactgtc ttctggactt ggtcttgaag tctgtacaga ttcagcctca     4560

gtagtagcga actgcactgc tgtttggttt ggagtacaaa ttagacttat agtcctcctg     4620

gaacttgagt tattaaaatc ataggaataa aattatggga tctcaacaaa gggtcgaggg     4680

tttgaggctt aaacaagcca acatatgaat atatgttttg tctcgctata ctgcacttac     4740

gctatccagt tgcaggtaat tttttgtctg ctagtagtgt tctagattat gtctttccaa     4800

agcgctgagg ctgtgcacct attctgtagt tgcagctgat gcctgaatgt atcctagctg     4860

acaaattatt gattaataag aacttgaatt tctggaagat tcttactgtt aaccaaattt     4920

tgagcaagga gtctcaaagg taattctgaa ccagaattac atgttaatga acagtgtacc     4980

ttttaacagt gtaaatcacg gaatatccgt gaagggattt cttaatttat tttttaccgg     5040

ttgattgaaa tatcagttaa aggttgccag catggttgca gataaactga tgtttgaaat     5100

tcgctgaaat acttaatgtg gaataggata atatacttcc aatgccctca aggctgtgac     5160

cttacagcca ttttacatag cacatcattc ctcctatagg gatgaacttt ttcctggcac     5220

gaaaagtagc cgctctggtt gaagctttgc ttattgtaac aggcttttat ttccaggtaa     5280

tatgtcttgg aagacttaat tctgattaga gatatagata ttactggaaa ctaattgttt     5340

tttttctatt gtactctgct ttatcaaaga agtaaaacat ttaaatcgta ctacagaaat     5400

taagatgttg tcttgcgatc cttaataaat gaatgatttc cctttaatac ggaaaaaaaa     5460

aaaaaaa                                                               5467


<210>  1408
<211>  5497
<212>  DNA
<213>  homo sapiens

<400>  1408
agttccggcc catgttgttt cggccgagga gccgtcgccg ccatttcaag accgtactag       60

gtagatggtc aattagagtt cccagggttt gaagcctgta actgctgccg ccgctcaagc      120

cctccagagc attgctacgg ctgctgccct tgtactacta cctccaaata cgttcttgct      180

ggtagtggcg gcagcaggac caattacctc ttttttgctc tccctcgaga agctccagat      240

ggcgtcttcc gtgggcaacg tggccgacag cacagaacca acgaaacgta tgctttcctt      300

ccaagggtta gctgagttgg cacatcgaga atatcaggca ggagattttg aggcagctga      360

gagacactgc atgcagctct ggagacaaga gccagacaat actggtgtgc ttttattact      420

ttcatctata cacttccagt gtcgaaggct ggacagatct gctcacttta gcactctggc      480

aattaaacag aacccccttc tggcagaagc ttattcgaat ttggggaatg tgtacaagga      540

aagagggcag ttgcaggagg caattgagca ttatcgacat gcattgcgtc tcaaacctga      600

tttcatcgat ggttatatta acctggcagc cgccttggta gcagcgggtg acatggaagg      660

ggcagtacaa gcttacgtct ctgctcttca gtacaatcct gatttgtact gtgttcgcag      720

tgacctgggg aacctgctca aagccctggg tcgcttggaa gaagccaagg catgttattt      780

gaaagcaatt gagacgcaac cgaactttgc agtagcttgg agtaatcttg gctgtgtttt      840

caatgcacaa ggggaaattt ggcttgcaat tcatcacttt gaaaaggctg tcacccttga      900

cccaaacttt ctggatgctt atatcaattt aggaaatgtc ttgaaagagg cacgcatttt      960

tgacagagct gtggcagctt atcttcgtgc cctaagtttg agtccaaatc acgcagtggt     1020

gcacggcaac ctggcttgtg tatactatga gcaaggcctg atagatctgg caatagacac     1080

ctacaggcgg gctatcgaac tacaaccaca tttccctgat gcttactgca acctagccaa     1140

tgctctcaaa gagaagggca gtgttgctga agcagaagat tgttataata cagctctccg     1200

tctgtgtccc acccatgcag actctctgaa taacctagcc aatatcaaac gagaacaggg     1260

aaacattgaa gaggcagttc gcttgtatcg taaagcatta gaagtcttcc cagagtttgc     1320

tgctgcccat tcaaatttag caagtgtact gcagcagcag ggaaaactgc aggaagctct     1380

gatgcattat aaggaggcta ttcgaatcag tcctaccttt gctgatgcct actctaatat     1440

gggaaacact ctaaaggaga tgcaggatgt tcagggagcc ttgcagtgtt atacgcgtgc     1500

catccaaatt aatcctgcat ttgcagatgc acatagcaat ctggcttcca ttcataagga     1560

ttcagggaat attccagaag ccatagcttc ttaccgcacg gctctgaaac ttaagcctga     1620

ttttcctgat gcttattgta acttggctca ttgcctgcag attgtctgtg attggacaga     1680

ctatgatgag cgaatgaaga agttggtcag tattgtggct gaccagttag agaagaatag     1740

gttgccttct gtgcatcctc atcatagtat gctatatcct ctttctcatg gcttcaggaa     1800

ggctattgct gagaggcacg gcaacctgtg cttagataag attaatgttc ttcataaacc     1860

accatatgaa catccaaaag acttgaagct cagtgatggt cggctgcgtg taggatatgt     1920

gagttccgac tttgggaatc atcctacttc tcaccttatg cagtctattc caggcatgca     1980

caatcctgat aaatttgagg tgttctgtta tgccctgagc ccagacgatg gcacaaactt     2040

ccgagtgaag gtgatggcag aagccaatca tttcattgat ctttctcaga ttccatgcaa     2100

tggaaaagca gctgatcgca tccatcagga tggaattcat atccttgtaa atatgaatgg     2160

ctatactaag ggcgctcgaa atgagctttt tgctctcagg ccagctccta ttcaggcaat     2220

gtggctggga taccctggga cgagtggtgc gcttttcatg gattatatta tcactgatca     2280

ggaaacttcg ccagctgaag ttgctgagca gtattccgag aaattggctt atatgcccca     2340

cacttttttt attggtgatc atgctaatat gttccctcac ctgaagaaaa aagcagtcat     2400

cgattttaag tccaatgggc acatttatga caatcggata gttctgaatg gcatcgacct     2460

caaagcattt cttgatagtc taccagatgt gaaaattgtc aagatgaagt gtcctgatgg     2520

aggagacaat gcagatagca gtaacacagc tcttaatatg cctgttattc ctatgaatac     2580

tattgcagaa gcagttattg aaatgattaa ccgaggacag attcaaataa caattaatgg     2640

attcagtatt agcaatggac tggcaactac tcagatcaac aataaggctg caactggaga     2700

ggaggttccc cgtaccatta ttgtaaccac ccgttctcag tacgggttac cagaagatgc     2760

catcgtatac tgtaacttta atcagttgta taaaattgac ccttctactt tgcagatgtg     2820

ggcaaacatt ctgaagcgtg ttcccaatag tgtactctgg ctgttgcgtt ttccagcagt     2880

aggagaacct aatattcaac agtatgcaca aaacatgggc ctgccccaga accgtatcat     2940

tttttcacct gttgctccta aagaggaaca cgtcaggaga ggccagctgg ctgatgtctg     3000

cttggacact ccactctgta atgggcacac cacagggatg gatgtcctct gggcagggac     3060

ccccatggtg actatgccag gagagactct tgcttctcga gttgcagcat cccagctcac     3120

ttgcttaggt tgtcttgagc ttattgctaa aaacagacaa gaatatgaag acatagctgt     3180

gaagctggga actgatctag aatacctgaa gaaagttcgt ggcaaagtct ggaagcaaag     3240

aatatctagc cctctgttca acaccaaaca atacacaatg gaactagagc ggctctatct     3300

acagatgtgg gagcattatg cagctggcaa caaacctgac cacatgatta agcctgttga     3360

agtcactgag tcagcataaa taaagactgc acaggagaat tacccctata cctgagcctc     3420

aaccttctgg gggaaaggga actagataac atacttctta cttgtctgta cagtaccttg     3480

ttgcagatgg gtgatatata atggtaatag aatagcacag ccagacttgc ttcctgcatg     3540

gtagggagag acacaaaaga tgggaaactg cttttccaca aggaatctcc gtagaatttt     3600

gcggcgacca gatggtgcat aggtctggaa ggtctgatct cccttggtct tccatgggat     3660

ggttagtgtg gaggggagat atagattgtc cggccgcttt gtgattccat ggattgattc     3720

agtcttctgg attttttttt ctttatattt tgggtactgg agcttttaaa aatgtttggt     3780

ttcaggtatt tttattcatg tgaagtgtat atgattctct tgagataagg ttttaagcta     3840

aaatgttact ccctgtttta gtttctgaac tctgacagat tgacagggac tttgctggtg     3900

tagtcttttt ataggtttta taaaccactt gagcctatat cagtcgtttt agtgtctgac     3960

ctaatatttg gagctatcag tgctttgttg atttagatga tgactcaaga ttttttctgg     4020

tccatttccc atttcctttt cttccctgac ccccataccc tcacccttaa aattctcctg     4080

taactcaact aacaaaatca agcctgattc aaaacatcct agggtgtttt aaacacacca     4140

tctggtgcca aatgaagatt tttaggagtg attactaatt atcaagggca cagttgtggt     4200

actgtcattg ataataatat agtttttttt tttttcctaa ttttgacctg tttcaccagt     4260

gttttaccct tgactgcccc ttctatgctg cttccaaaag tgatagtgtg tgtaagattt     4320

ttaccttcct ttctaaagtt tttttttttt ttttttaagt gagtcctgtt cttcctattt     4380

ctttcagcag aaatgaaatc ccaggtaagt ataagtattc aagtatttga tcagtaagtc     4440

acagttatct ccagtgcatt aaataacctt catcaagaaa taggttatag gtaaaatctc     4500

tgaaggatca tctatgtatt caagtaatta ttttttagat aataactgtc ttctggactt     4560

ggtcttgaag tctgtacaga ttcagcctca gtagtagcga actgcactgc tgtttggttt     4620

ggagtacaaa ttagacttat agtcctcctg gaacttgagt tattaaaatc ataggaataa     4680

aattatggga tctcaacaaa gggtcgaggg tttgaggctt aaacaagcca acatatgaat     4740

atatgttttg tctcgctata ctgcacttac gctatccagt tgcaggtaat tttttgtctg     4800

ctagtagtgt tctagattat gtctttccaa agcgctgagg ctgtgcacct attctgtagt     4860

tgcagctgat gcctgaatgt atcctagctg acaaattatt gattaataag aacttgaatt     4920

tctggaagat tcttactgtt aaccaaattt tgagcaagga gtctcaaagg taattctgaa     4980

ccagaattac atgttaatga acagtgtacc ttttaacagt gtaaatcacg gaatatccgt     5040

gaagggattt cttaatttat tttttaccgg ttgattgaaa tatcagttaa aggttgccag     5100

catggttgca gataaactga tgtttgaaat tcgctgaaat acttaatgtg gaataggata     5160

atatacttcc aatgccctca aggctgtgac cttacagcca ttttacatag cacatcattc     5220

ctcctatagg gatgaacttt ttcctggcac gaaaagtagc cgctctggtt gaagctttgc     5280

ttattgtaac aggcttttat ttccaggtaa tatgtcttgg aagacttaat tctgattaga     5340

gatatagata ttactggaaa ctaattgttt tttttctatt gtactctgct ttatcaaaga     5400

agtaaaacat ttaaatcgta ctacagaaat taagatgttg tcttgcgatc cttaataaat     5460

gaatgatttc cctttaatac ggaaaaaaaa aaaaaaa                              5497


<210>  1409
<211>  6308
<212>  DNA
<213>  homo sapiens

<400>  1409
gctcctcgcc tggccgtgat atcaatggcg caggcttcac ttctgctgtg gcggtgactg       60

aggcctttct ggtgacctca gcccaacaca ggccgtctcc ggagcttccc ggtagtggcc      120

ccggattccc acggtctttg tcattggctg tcagctagca ggcctggccg ctcccgtgcg      180

gagagaccat ctcttcaggg caatgtccag gccgagcagc gtctccccgc ggcagccggc      240

tcctggcggt ggcggaggcg gcggcccctc gccttgtggc cctgggggcg gcggccgggc      300

caaggggctg aaggacattc gcattgatga ggaggtgaag atcgcagtca atatcgcgct      360

ggagcgcttc cgatacgggg accagagaga aatggaattt ccttcttctt tgaccagtac      420

tgaaagagcc tttattcatc gactcagtca gtctcttggt ttggtctcta aaagtaaagg      480

aaagggagca aatagatacc taactgtgaa gaagaaagat ggatcagaaa cagctcatgc      540

aatgatgacc tgtaatttga ctcataatac aaaacatgct gttaggagcc taattcaaag      600

atttcctgtc accaataaag agcgtacaga acttctgcct aaaacagaaa gaggaaatgt      660

gtttgcagtt gaagctgaaa accgggaaat gagcaagaca agtgggcgac tcaacaatgg      720

catacctcag attccagtga aaagaggaga atccgaattt gattctttta ggcagtcttt      780

accagtgttt gagaaacagg aagaaattgt taaaataatt aaggaaaata aagtagtttt      840

gattgtagga gaaactgggt ctggaaagac cacacagatt cctcagttcc ttttagatga      900

ttgctttaaa aatggtatcc cctgccgtat attttgtact caaccaagac gattggcagc      960

tatcgctgtg gctgaaagag ttgccgcaga gagacgggaa aggattggtc aaacaattgg     1020

ttatcagatc cgattagaaa gcagggtttc tccaaagaca cttctgacat tttgtactaa     1080

tggggtattg cttcgtacat tgatggcagg agatagtacg ttgtcgactg tgacacatgt     1140

tatcgtggat gaagtgcatg aaagggatcg atttagtgat tttttactta caaagttaag     1200

agatttgttg caaaagcacc caactttgaa actaattctt tctagtgctg ccttggatgt     1260

aaatctcttt ataagatatt ttggaagttg tccagtgata tatatacagg gaagaccatt     1320

tgaagtaaaa gaaatgtttc tggaagatat tttaagaaca actggatata caaacaaaga     1380

aatgttaaaa tataaaaagg aaaaacagca agaagagaaa caacaaacca cacttacaga     1440

atggtactca gctcaagaaa atagtttcaa gcctgaatct cagaggcaga gaactgttct     1500

aaatgtgact gatgagtatg acttactgga tgatggtggt gatgctgtct tcagtcagct     1560

gactgaaaaa gatgtgaatt gccttgaacc atggttaata aaggaaatgg atgcttgcct     1620

ttctgatata tggctacata aagatattga tgcctttgct caggtctttc atctcatttt     1680

aactgaaaat gttagtgttg attacagaca tagtgaaacc agtgcaacag ctctgatggt     1740

tgctgcagga cgtggctttg caagtcaagt agaacagtta atcagtatgg gagccaatgt     1800

ccatagtaaa gcatcaaatg gctggatggc attggattgg gctaaacact ttgggcagac     1860

tgaaattgtg gatcttctag aatcttacag tgctacactg gaatttggaa atctagatga     1920

aagttctctg gttcaaacaa atggaagtga cctcagtgct gaagacagag agctcctgaa     1980

agcttatcat catagtttcg atgatgaaaa agtagacttg gatttgatca tgcatcttct     2040

atacaatatc tgccatagtt gtgatgctgg tgcagtacta atttttctgc ctggatatga     2100

cgaaattgtt ggactgagag atcgcatcct gtttgatgac aagcggtttg ctgacagtac     2160

acatagatac caagtcttta tgcttcattc aaatatgcaa acatccgatc aaaagaaagt     2220

attaaaaaac ccacctgcag gtgttcgaaa aataattctt tccaccaata ttgctgaaac     2280

cagcatcaca gtcaatgatg ttgtctttgt tattgattct ggtaaggtga aagagaaatc     2340

ctttgatgct ctgaattttg ttacaatgtt aaaaatggta tggatttcca aagctagtgc     2400

catacagcgg aaaggcaggg cagggcgatg tagacctgga atttgttttc gtctgttcag     2460

tagactccga ttccagaata tgttggaatt tcagactccg gaacttttga gaatgccatt     2520

acaggaactt tgcttacata ccaagctgtt agccccagtt aattgtccca ttgctgattt     2580

tcttatgaaa gctcctgaac ctccaccagc tttaattgta agaaatgctg tacaaatgct     2640

taagacaata gatgcaatgg atacatggga agatctgact gaacttgggt atcatttggc     2700

tgacttgcca gtagaaccac atcttggtaa aatggtcttg tgtgctgttg ttttaaagtg     2760

tctggacccc atccttacaa ttgcttgcac actagcttat cgagatcctt ttgtactacc     2820

tactcaggcc tctcaaaaac gtgcagctat gctttgtagg aaacgtttta ctgcaggagc     2880

tttcagtgac catatggcac ttctcagagc attccaggcc tggcaaaaag cacgaagtga     2940

tgggtgggag cgagcctttt gtgaaaagaa ttttctttca caggctacta tggaaataat     3000

cataggcatg agaacacagt tgcttggtca acttagagca tcaggttttg ttagagcacg     3060

aggtggtggt gacattcggg acgttaacac aaactctgag aattgggctg tcgttaaagc     3120

tgcattggtg gcaggcatgt atcctaattt agtccacgtg gacagagaga atctagtgtt     3180

gacagggcca aaggagaaaa aagtacgatt tcatcctgct tcagttctca gtcagcctca     3240

atataaaaag attcctccag ccaatggtca agctgcagca attaaggcac tgcccacaga     3300

ttggcttatt tatgatgaaa tgaccagagc ccatagaata gctaatatta gatgttgttc     3360

agcagtgacg cctgtcacta tattggtatt ctgtggacca gctagattgg caagtaatgc     3420

tcttcaggaa ccttcatcct ttagagtgga tggcattccc aatgacagta gtgatagtga     3480

aatggaggac aaaactacag ctaatttggc agccttgaaa cttgatgagt ggctccattt     3540

cacactggag ccagaggcag ctagtttatt gctgcagctc agacagaagt ggcatagctt     3600

atttttacgc cgaatgagag ctccatctaa accttggtct caagttgatg aagctaccat     3660

aagagcaatt atagctgttt taagcactga agaacagtct gcaggtttac aacaaccatc     3720

tgggattggc caaaggccaa ggcctatgtc ttcagaagag cttcctttgg cctcatcttg     3780

gaggtcaaat aatagtagga aaagttcagc agatactgaa ttttctgatg agtgtactac     3840

tgcagaaaga gtactgatga aatctccatc tccagcatta cacccacctc agaagtacaa     3900

agatagagga attttacatc ctaaacgagg tactgaggac cgatcagatc agtcttctct     3960

gaaatctaca gacagcagta gttacccaag tccttgtgct agtccttctc ctccatcctc     4020

aggaaagggc tcaaaatctc cttcgccaag accaaacatg cctgttcgat acttcataat     4080

gaagagtagc aatttgagaa accttgaaat ttctcaacag aagggtatct ggtctacaac     4140

tcctagtaat gaacggaagc taaatcgagc cttttgggaa agcagcatag tttacttggt     4200

attttctgtt caaggatctg gacatttcca gggattttct aggatgtctt ctgagattgg     4260

aagggaaaag agtcaggact ggggctctgc tggactagga ggagtattta aggtggagtg     4320

gatacgaaaa gaaagccttc cctttcaatt tgcacaccat ttactcaatc catggaatga     4380

caacaagaaa gtgcagataa gcagggatgg gcaggaacta gaacctctgg ttggtgaaca     4440

gttgctccag ttatgggaac gtcttccctt gggagaaaaa aacacaactg attgacactc     4500

agaactctta gctgtggaag aacatcatgc ctatttataa ccactgaatg cactgacttt     4560

caaaaactga ggtggggtgt gtgttacgaa tgggcttttt aacactttta gagtgttgct     4620

ttagaactac catcttcata tacaggagaa aggaagcatt taaattttta tagtgattat     4680

agagaatgat tatatgatgt ttgtaatgaa taaaatagta gtttcattat ttggcacaat     4740

agcagtttat tttaaacaaa caatttgaag ttaaacattt catttttaaa aacactgaat     4800

tacagttctt attgatgact ttttaatgca gagtaagttg tttaagaaag gcctgaatat     4860

atcagaacat ctgagcacca ttttagaaga gtcaactctt aagattatca ttagaaaaca     4920

aatacgtcaa cacctatgaa aagaagcggg gaaaacaaca acaaggacaa caacaaaaaa     4980

ccagtgaaat tctacaagtg tcccttttaa aaatagtgtg tgctaactaa gggctattca     5040

ttctgccatt tttaacttga gacacattta agaataaagt tggatgttct ttttctgtga     5100

ttatgaaatg caataaaatc tgaataaagg gcaaagtttc ttcctgatca gattagatta     5160

agtgcttagt tttattccta attctgcccc ttttaacctg atgtgtacct tactctttcc     5220

tccctctctt cctcccttcc tcctctcccc gctcctttcc tgcatttctc cctccctcct     5280

tccctcgtca catctcttat atgagcacag taattatgac ctttttgttt tggctacaac     5340

ttgattgaaa caagttcaaa atttaaacaa gttcatacaa gtttttaaaa attctcaact     5400

ggtagcttgc ttgctgtgcg tcttccaaac taaagcctgc aagcgccaca attctaagtg     5460

ccgccttcca ttttttttca gtatgttttc actggcttat gttttcagat atgattttcc     5520

tttttcgcat atatggttta ataaatgggg gataattttt tttttgtaaa tccgtgcttg     5580

tgccaagtct catatttctt tgccatctca gaattatctt tttaccacca ctgtttataa     5640

aatttcctta gagacttttt gaagggaaaa tagagcaaca gggaaaaatg aaagaaatgt     5700

cttggttact gagctctaaa tagacaggtt tgatggcact tctcatgata cattttagtt     5760

attcttataa aagcaaacag gcaaacatga gtgtaaatta aagacaaaaa gaaaactctg     5820

gttttatatt tgagaacacg tgaaaaatca tgggtcaaca taaaatcttg agaaccttct     5880

actttctctg ggaaagcatt atatagtggt gcattagttt agaaagtcag ctatgatttt     5940

gcctatagtt ctagttatta gctttggggt tttcttgtac tttaagacat acctgtaaat     6000

tgaacctatt tgaattatat tccactgtat gtgtattatg gctcttttcc tattagagca     6060

acttgtgttt ccctgataat gtgtacattt tttaggcatg tacttaatag ttcacaatgt     6120

tctaaatttg gaaggactta aaaaaaaaac ttgtttaaat ttccatctgt tttgtaatat     6180

ctagctctat atgtaaatga tgggtttgtt ggtatttaaa atgaatacaa cttgaatgta     6240

attaaagtgc tgttttttgg aagcgataaa ctttaaatat acttattaaa atgaaattct     6300

attaagtt                                                              6308


<210>  1410
<211>  2978
<212>  DNA
<213>  homo sapiens

<400>  1410
ggcgggcgct cggcgactcg tccccggggc cccgcgcggg cccgggcagc aggggcgtga       60

tgtcacggca gggagggggc gcgggagccg ccgggccggc ggggaggcgg gggaggtgtt      120

ttccagcttt aaaaaggcag gaggcagagc gcggccctgc gtcagagcga gactcagagg      180

ctccgaactc gccggcggag tcgccgcgcc agatcccagc agcagggcgc gggcaccggg      240

gcgcgggcag ggctcggagc caccgcgcag gtcctagggc cgcggccggg ccccgccacg      300

cgcgcacacg cccctcgatg actttcctcc ggggcgcgcg gcgctgagcc cggggcgagg      360

gctgtcttcc cggagacccg accccggcag cgcggggcgg ccgcttctcc tgtgcctccg      420

cccgccgctc cactccccgc cgccgccgcg cggatgccaa gcaccagctt tccagtccct      480

tccaagtttc cacttggccc tgcggctgcg gtcttcggga gaggagaaac tttggggccc      540

gcgccgcgcg ccggcggcac catgaagtca gcggaggaag aacactatgg ctatgcatcc      600

tccaacgtca gccccgccct gccgctcccc acggcgcact ccaccctgcc ggccccgtgc      660

cacaaccttc agacctccac accgggcatc atcccgccgg cggatcaccc ctcggggtac      720

ggagcagctt tggacggtgg gcccgcgggc tacttcctct cctccggcca caccaggcct      780

gatggggccc ctgccctgga gagtcctcgc atcgagataa cctcgtgctt gggcctgtac      840

cacaacaata accagttttt ccacgatgtg gaggtggaag acgtcctccc tagctccaaa      900

cggtccccct ccacggccac gctgagtctg cccagcctgg aggcctacag agacccctcg      960

tgcctgagcc cggccagcag cctgtcctcc cggagctgca actcagaggc ctcctcctac     1020

gagtccaact actcgtaccc gtacgcgtcc ccccagacgt cgccatggca gtctccctgc     1080

gtgtctccca agaccacgga ccccgaggag ggctttcccc gcgggctggg ggcctgcaca     1140

ctgctgggtt ccccgcggca ctccccctcc acctcgcccc gcgccagcgt cactgaggag     1200

agctggctgg gtgcccgctc ctccagaccc gcgtcccctt gcaacaagag gaagtacagc     1260

ctcaacggcc ggcagccgcc ctactcaccc caccactcgc ccacgccgtc cccgcacggc     1320

tccccgcggg tcagcgtgac cgacgactcg tggttgggca acaccaccca gtacaccagc     1380

tcggccatcg tggccgccat caacgcgctg accaccgaca gcagcctgga cctgggagat     1440

ggcgtccctg tcaagtcccg caagaccacc ctggagcagc cgccctcagt ggcgctcaag     1500

gtggagcccg tcggggagga cctgggcagc cccccgcccc cggccgactt cgcgcccgaa     1560

gactactcct ctttccagca catcaggaag ggcggcttct gcgaccagta cctggcggtg     1620

ccgcagcacc cctaccagtg ggcgaagccc aagcccctgt cccctacgtc ctacatgagc     1680

ccgaccctgc ccgccctgga ctggcagctg ccgtcccact caggcccgta tgagcttcgg     1740

attgaggtgc agcccaagtc ccaccaccga gcccactacg agacggaggg cagccggggg     1800

gccgtgaagg cgtcggccgg aggacacccc atcgtgcagc tgcatggcta cttggagaat     1860

gagccgctga tgctgcagct tttcattggg acggcggacg accgcctgct gcgcccgcac     1920

gccttctacc aggtgcaccg catcacaggg aagaccgtgt ccaccaccag ccacgaggcc     1980

atcctctcca acaccaaagt cctggagatc ccactcctgc cggagaacag catgcgagcc     2040

gtcattgact gtgccggaat cctgaaactc agaaactccg acattgaact tcggaaagga     2100

gagacggaca tcgggaggaa gaacacacgg gtacggctgg tgttccgcgt tcacgtcccg     2160

caacccagcg gccgcacgct gtccctgcag gtggcctcca accccatcga atgctcccag     2220

cgctcagctc aggagctgcc tctggtggag aagcagagca cggacagcta tccggtcgtg     2280

ggcgggaaga agatggtcct gtctggccac aacttcctgc aggactccaa ggtcattttc     2340

gtggagaaag ccccagatgg ccaccatgtc tgggagatgg aagcgaaaac tgaccgggac     2400

ctgtgcaagc cgaattctct ggtggttgag atcccgccat ttcggaatca gaggataacc     2460

agccccgttc acgtcagttt ctacgtctgc aacgggaaga gaaagcgaag ccagtaccag     2520

cgtttcacct accttcccgc caacggtaac gccatctttc taaccgtaag ccgtgaacat     2580

gagcgcgtgg ggtgcttttt ctaaagacgc agaaacgacg tcgccgtaaa gcagcgtggc     2640

gtgttgcaca tttaactgtg tgatgtcccg ttagtgagac cgagccatcg atgccctgaa     2700

aaggaaagga aaagggaagc ttcggatgca ttttccttga tccctgttgg gggtgggggg     2760

cgggggttgc atactcagat agtcacggtt attttgcttc ttgcgaatgt ataacagcca     2820

aggggaaaac atggctcttc tgctccaaaa aactgagggg gtcctggtgt gcatttgcac     2880

cctaaagctg cttacggtga aaaggcaaat aggtatagct attttgcagg cacctttagg     2940

aataaacttt gcttttaagc ctgtaaaaaa aaaaaaaa                             2978


<210>  1411
<211>  3471
<212>  DNA
<213>  homo sapiens

<400>  1411
taaatggcag ccaatggagg gtggtgttgc gcggggctgg gattagggcc ggggcgaatg       60

gctggcaatc ttactgggat tacagaacaa agagcctccc cgcgctcccg ctctccgctc      120

ctctccccgc gccgccccgc cctccgccgc agcccgcgcc gggggtgggg gccgccgagc      180

gccagccccc cggccggccg attccccccc cgcgccccct ccccgcgcct ccctccccgc      240

cctcgccgcg ccgccgtcct cgcctccctc tgcctctcct tcccccattc tcccggatta      300

attaaggagg cagcggcagg aggctgagtc ctggccgcgg gccggggccg gggcgccgct      360

ggcaggagcg cttggggatc ctccaaggcg accatggcct tgctgggtaa gcgctgtgac      420

gtccccacca acggctgcgg acccgaccgc tggaactccg cgttcacccg caaagacgag      480

atcatcacca gcctcgtgtc tgccttagac tccatgtgct cagcgctgtc caaactgaac      540

gccgaggtgg cctgtgtcgc cgtgcacgat gagagcgcct ttgtggtggg cacagagaag      600

gggagaatgt tcctgaatgc ccggaaggag ctacagtcag acttcctcag gttctgccga      660

gggcccccgt ggaaggatcc ggaggcagag caccccaaga aggtgcagcg gggcgagggt      720

ggaggccgta gcctccctcg gtcctccctg gaacatggct cagatgtgta ccttctgcgg      780

aagatggtag aggaggtgtt tgatgttctt tatagcgagg ccctgggaag ggccagtgtg      840

gtgccactgc cctatgagag gctgctcagg gagccagggc tgctggccgt gcaggggctg      900

cccgaaggcc tggccttccg aaggccagcc gagtatgacc ccaaggccct catggccatc      960

ctggaacaca gccaccgcat ccgcttcaag ctcaagaggc cacttgagga tggcgggcgg     1020

gactcgaagg ccctggtgga gctgaacggt gtctccctga ttcccaaggg gtcacgggac     1080

tgtggcctgc atggccaggc ccccaaggtg ccaccccagg acctgccccc aaccgccacc     1140

tcctcctcca tggccagctt cctgtacagc acggcgctcc ccaaccacgc catccgagag     1200

ctcaagcagg aagcaccttc ctgccccctt gcccccagcg acctgggcct gagtcggccc     1260

atgccagagc ccaaggccac cggtgcccaa gacttctccg actgttgtgg acagaagccc     1320

actgggcctg gtgggcctct catccagaac gtccatgcct ccaagcgcat tctcttctcc     1380

atcgtccatg acaagtcaga gaagtgggac gccttcataa aggaaaccga ggacatcaac     1440

acgctccggg agtgtgtgca gatcctgttt aacagcagat atgcggaagc cctgggcctg     1500

gaccacatgg tccccgtgcc ctaccggaag attgcctgtg acccggaggc tgtggagatc     1560

gtgggcatcc cggacaagat ccccttcaag cgcccctgca cttatggagt ccccaagctg     1620

aagcggatcc tggaggagcg ccatagtatc cacttcatca ttaagaggat gtttgatgag     1680

cgaattttca cagggaacaa gtttaccaaa gacaccacga agctggagcc agccagcccg     1740

ccagaggaca cctctgcaga ggtctctagg gccaccgtcc ttgaccttgc tgggaatgct     1800

cggtcagaca agggcagcat gtctgaagac tgtgggccag gaacctccgg ggagctgggc     1860

gggctgaggc cgatcaaaat tgagccagag gatctggaca tcattcaggt caccgtccca     1920

gacccctcgc caacctctga ggaaatgaca gactcgatgc ctgggcacct gccatcggag     1980

gattctggtt atgggatgga gatgctgaca gacaaaggtc tgagtgagga cgcgcggccc     2040

gaggagaggc ccgtggagga cagccacggt gacgtgatcc ggcccctgcg gaagcaggtg     2100

gagctgctct tcaacacacg atacgccaag gccattggca tctcggagcc cgtcaaggtg     2160

ccgtactcca agtttctgat gcacccggag gagctgtttg tggtgggact gcctgaaggc     2220

atctccctcc gcaggcccaa ctgcttcggg atcgccaagc tccggaagat tctggaggcc     2280

agcaacagca tccagtttgt catcaagagg cccgagctgc tcactgaggg agtcaaagag     2340

cccatcatgg atagtcaagg aactgcctcc tcacttggct tctctccccc tgccctgccc     2400

ccagagaggg attccgggga ccctctggtg gacgagagcc tgaagagaca gggctttcaa     2460

gaaaattatg acgcgaggct ctcacggatc gacatcgcca acacactaag ggagcaggtc     2520

caggaccttt tcaataagaa atacggggaa gccttgggca tcaagtaccc ggtccaggtc     2580

ccctacaagc ggatcaagag taaccccggc tccgtgatca tcgaggggct gcccccagga     2640

atcccgttcc gaaagccctg taccttcggc tcccagaacc tggagaggat tcttgctgtg     2700

gctgacaaga tcaagttcac agtcaccagg cctttccaag gactcatccc aaagcctgat     2760

gaagatgacg ccaacagact cggggagaag gtgatcctgc gggagcaggt gaaggaactc     2820

ttcaacgaga aatacggtga ggccctgggc ctgaaccggc cggtgctggt cccttataaa     2880

ctaatccggg acagcccaga cgccgtggag gtcacgggtc tgcctgatga catccccttc     2940

cggaacccca acacgtacga catccaccgg ctggagaaga tcctgaaggc ccgagagcat     3000

gtccgcatgg tcatcattaa ccagctccaa ccctttgcag aaatctgcaa tgatgccaag     3060

gtgccagcca aagacagcag cattcccaag cgcaagagaa agcgggtctc ggaaggaaat     3120

tccgtctcct cttcctcctc gtcttcctct tcctcgtcct ctaacccgga ttcagtggca     3180

tcggccaacc agatctcact cgtgcaatgg ccaatgtaca tggtggacta tgccggcctg     3240

aacgtgcagc tcccgggacc tcttaattac tagacctcag tactgaatca ggacctcact     3300

cagaaagact aaaggaaatg taatttatgt acaaaatgta tattcggata tgtatcgatg     3360

ccttttagtt tttccaatga tttttacact atattcctgc caccaaggcc tttttaaata     3420

agtaaaaaaa gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a              3471


<210>  1412
<211>  4865
<212>  DNA
<213>  homo sapiens

<400>  1412
gcagtgccgc cttttttttt tttttgcatc ccattttttt aaatttgcaa ttttatattt       60

tgcaaatatt ttgagagaca ttgatttttc tccccgtgct cccccgttct tccctgcgga      120

gtgcgctgcg ccgcccagcc ctgtcgcccc ccggaggtga tccctccctc ctgcctgccc      180

gccagcctga cctgtgcccg gctcgcgggc cgcagcctcg gccccggcgc gcccccggca      240

gctctcggcg cgatgagcat agagacgcta ctggaggcgg cccgcttcct ggaatggcaa      300

gcgcagcaac aacagagagc acgtgaggag caggagcggc ttcgcttgga gcaggagcga      360

gagcaggaac agaagaaggc caatagcctg gccaggctgg cacataccct tcctgtggag      420

gaaccccgca tggaggcgcc acccctgcct ctgtctccac cggctccccc gccggcaccc      480

ccaccaccac ttgccacccc tgccccactg actgtcatcc ctatccctgt ggtgaccaac      540

tcccctcagc ctctaccccc acccccaccc ttgcccgcgg cagcccagcc tctgcccctg      600

gcgcctcgtc agccggccct ggttggcgcc cccggactca gcattaagga gcctgccccc      660

ctgcccagca ggccgcaggt gcccacccct gctcccctac tgccggactc gaaggccacc      720

attccaccca atggcagccc caagcctttg cagcccctcc ccacgcctgt cctgaccata      780

gcgccacacc ctggagtcca gcctcagctg gccccccagc agccgccccc acccacgctg      840

gggaccctga agttggcacc agctgaagaa gtcaaatcca gtgaacagaa gaagaggccc      900

ggggggatcg gaaccagaga agtccacaac aaattggaga agaacaggag ggcccatctg      960

aaagagtgct ttgagaccct gaagcggaac atccccaacg tggatgacaa gaagacgtcc     1020

aatctgagcg tgctgcggac ggcgctgcgg tacatccagt ccctgaagag gaaggagaag     1080

gaatatgagc atgaaatgga gcggctggca cgtgagaaga ttgccacgca gcagcggctg     1140

gcagagctca agcacgagct gagccagtgg atggacgtac tggagattga ccgcgtgctg     1200

cggcagacgg gccagcccga ggatgaccag gcctccacct ccaccgcctc tgagggtgag     1260

gacaacatag acgaggatat ggaggaggac cgggcgggcc tgggcccacc taagctgagc     1320

catcgtcccc agccggagct gctgaagtcc accctgccac cccccagcac cacccctgcg     1380

cctctgcctc cacacccaca ccctcacccc cactccgtgg ccctacctcc tgcccacctc     1440

cccgtgcagc agcagcagcc acagcagaag acccctctgc cagcccctcc tcccccaccg     1500

gctgcccctg cccagacact ggtgccagct ccagcccatc tggtggcgac ggctgggggt     1560

ggctccacgg tcatcgccca cacagccacc actcacgctt cagtcatcca gactgtgaac     1620

cacgttctgc aggggccagg cggcaagcac atcgcccaca tcgccccctc ggcccccagc     1680

cctgcggtgc aactggcgcc tgccacaccc cccattgggc acatcactgt gcaccctgcc     1740

accctcaacc atgtggccca cctgggctcc cagctgccct tgtacccgca gcccgtggca     1800

gtgagccaca tcgcccacac cctctcgcac cagcaagtca acggcacggc cggcctgggg     1860

cccccggcta ctgtcatggc aaagccggcc gtgggggctc aggtggtgca ccacccccag     1920

ctggtgggcc agaccgtgct caaccctgtg accatggtca ccatgccctc cttcccagtc     1980

agcacactca agctggcttg aggacgaggc cactcagagg cccccagtgg ggacagggag     2040

ggggacctgt cccccactct ctcacccacc agctccacac attccagcca ggcccaggcc     2100

agccccccca cccaccccca ggcctcctag gggaaggggg tgcaaagact ctgagccaag     2160

ggagggaagg gccaccctgc tgcactagga cttggtaaga tgactctgag aaaatgcgag     2220

actctgatgg aatgtgccac ctgtccggcc cagtgccagc tccagtgccg ctcctgcttc     2280

ccctccctac cctcggaaat cagtgcgatg tggacgtcac gctccctgac ttctcccccg     2340

ccctgccccg ccttcgtgtg ctgctgctgc tattgctgtc tggtgaggtg gcccaggccc     2400

ccggctttcc tccggagcct catgttctct tcccaggcct ttggagggga aatggggaaa     2460

gcagaactga agccacttgg cccagaaagc tgcggattgg ggtgataagg ggccttgctc     2520

tgagcacagg tgacagatca taggaagtgg ctggtctgga gtcccacccg gacaggtggg     2580

gcctcagcct ggggctctct gacccggttg cagtcactgt gattcgttac cgtagatact     2640

acttaaaatg attctctacc aacaataaac caaacccagc cactgccaag cttcctgtgc     2700

cctcacccca atccctgcca ctgggctctg gacctcagga gggcaggctg aggtggggaa     2760

ggagggactt ggctgtcctt ccccttcccc gtcccctgca gcctgggtct ggatgggagg     2820

agagccactg ggcccctgtc cccagtcccc agtccccagc cctgggcttg gctcttggct     2880

tccagaaggc agcaaagagg ggcgctgtcc tgcgttcagc ccctgatctc tgacctctgc     2940

tgagtgctgg gcactgctcc aagggacagg tgggcctggc ggcctgtggg tttgggtgcc     3000

tcctgcagtt tgggagacat ggaccagcat ctggtcttgt ttccaggagc atagaagcca     3060

catcgttgag acatcaggaa ggtaaaaacc cagcggctta gccaagccct aagcctgtcc     3120

ccagaccaac cctgggacct atacagaaca gagggccaga gctagggctg ctgcttctgc     3180

tccagcccct ttgcctctgt cctcccatcc cctcaacacc ctgcttctcc cggggacgct     3240

tttgagtggg ccctgcccgg ggagctgcag agcagcagca cctttctctg agaagaggtc     3300

cttggttggg tcaaggacag ggctgagcgt ggaaggggga ggagtcaggg gctctgtgtt     3360

aggatgcggc tttctctgcc tctgggcagc ctgctttggc ctttccttgt atgtgggtgt     3420

ttattacaag tggctttgtg tcagacacgc tcggctcccc acctggacac acactcacca     3480

gtggcctttc agtgtagcgg gaggaagccg gtgtccctgg atgtgaagct cacactgatg     3540

ggctggggca ggggcctggg ccggcgaggg ggccgggggg aggggacaga gctgaggatt     3600

tcctggagtg ccctgcaggc acagaggagg tcagcaaagg tcttgaatag attttctctg     3660

gaaataaaga atccttagat gcctaaaaat tcccttcctg ttccctcctg gtcctggaca     3720

cctcccaggg gactgttcct tatttctctc tcctggtgtg ggtaaaggga cagttacaaa     3780

ccaggtcacc atcctcagag gctgagccct gtacccaccc cagcacagcc acctccgcca     3840

gaccccgtgg ctctgggaga gccagctttg ctattcccat tgtgacagcg atggcaggcc     3900

tgacccacgg ggcagttaga gcagcctcgt ggagctcgcc cctcccctca gcctgcccac     3960

ctctccctgc atcctgaggc cagtggcccc cgggcctgca cagatacctc atcatccacc     4020

cgctgcccct ccccgtccct gtcccccagc atcgggggcc tgcaaatcta gtgccgaatg     4080

actatgtcca gattggtgac gatgggtgtt gctgtttttc ttgtcgtttg tgaacgctgt     4140

gatgctgtgt gcccaagtgg gcagtcacca cccagccctt ccttgggcgt ctcccccaga     4200

gtgctgtcgg gaccacatct gtcctcaccc tgtgggaccg cctggccctc cctccctagc     4260

ccttccagcc tgggacacac acacacacac acacacacac acacgcacgc acacgcacac     4320

atcttacctc tcatgcgtgt tttacctttt gatgttcaga gtggctcact ggctgggagt     4380

ccttacctcg gggagagggg gaggttggtt ccttgggggg ccaaagaagg cagggaatgc     4440

ctggagggta actggggggc caccatgacc ccttctctct ccagaaacag ctgcttctcc     4500

ccccatccca gggtcccacc cccaaccccc agaggtggcc cttgtttaca gtgaggactc     4560

ggccactgtg tctctgtttc ctgaaatata aactgtagcg accccagact gtagagattt     4620

ttatgtgttt ggatacatct gctgtgtgga aaaaaaaaaa aactacaaaa accctaattt     4680

tgtacatact gtatttttac tattgaactg tattctagtg gctgttcatg ctccaagact     4740

ttagttaccg agacatgaat actatccatg taataagcac ttgcctggaa taaaatataa     4800

aactgaaata aacctgcact gaaacctgag atggagctgc caaaaaaaaa aaaaaaaaaa     4860

aaaaa                                                                 4865


<210>  1413
<211>  4865
<212>  DNA
<213>  homo sapiens

<400>  1413
gcagtgccgc cttttttttt tttttgcatc ccattttttt aaatttgcaa ttttatattt       60

tgcaaatatt ttgagagaca ttgatttttc tccccgtgct cccccgttct tccctgcgga      120

gtgcgctgcg ccgcccagcc ctgtcgcccc ccggaggtga tccctccctc ctgcctgccc      180

gccagcctga cctgtgcccg gctcgcgggc cgcagcctcg gccccggcgc gcccccggca      240

gctctcggcg cgatgagcat agagacgcta ctggaggcgg cccgcttcct ggaatggcaa      300

gcgcagcaac aacagagagc acgtgaggag caggagcggc ttcgcttgga gcaggagcga      360

gagcaggaac agaagaaggc caatagcctg gccaggctgg cacataccct tcctgtggag      420

gaaccccgca tggaggcgcc acccctgcct ctgtctccac cggctccccc gccggcaccc      480

ccaccaccac ttgccacccc tgccccactg actgtcatcc ctatccctgt ggtgaccaac      540

tcccctcagc ctctaccccc acccccaccc ttgcccgcgg cagcccagcc tctgcccctg      600

gcgcctcgtc agccggccct ggttggcgcc cccggactca gcattaagga gcctgccccc      660

ctgcccagca ggccgcaggt gcccacccct gctcccctac tgccggactc gaaggccacc      720

attccaccca atggcagccc caagcctttg cagcccctcc ccacgcctgt cctgaccata      780

gcgccacacc ctggagtcca gcctcagctg gccccccagc agccgccccc acccacgctg      840

gggaccctga agttggcacc agctgaagaa gtcaaatcca gtgaacagaa gaagaggccc      900

ggggggatcg gaaccagaga agtccacaac aaattggaga agaacaggag ggcccatctg      960

aaagagtgct ttgagaccct gaagcggaac atccccaacg tggatgacaa gaagacgtcc     1020

aatctgagcg tgctgcggac ggcgctgcgg tacatccagt ccctgaagag gaaggagaag     1080

gaatatgagc atgaaatgga gcggctggca cgtgagaaga ttgccacgca gcagcggctg     1140

gcagagctca agcacgagct gagccagtgg atggacgtac tggagattga ccgcgtgctg     1200

cggcagacgg gccagcccga ggatgaccag gcctccacct ccaccgcctc tgagggtgag     1260

gacaacatag acgaggatat ggaggaggac cgggcgggcc tgggcccacc taagctgagc     1320

catcgtcccc agccggagct gctgaagtcc accctgccac cccccagcac cacccctgcg     1380

cctctgcctc cacacccaca ccctcacccc cactccgtgg ccctacctcc tgcccacctc     1440

cccgtgcagc agcagcagcc acagcagaag acccctctgc cagcccctcc tcccccaccg     1500

gctgcccctg cccagacact ggtgccagct ccagcccatc tggtggcgac ggctgggggt     1560

ggctccacgg tcatcgccca cacagccacc actcacgctt cagtcatcca gactgtgaac     1620

cacgttctgc aggggccagg cggcaagcac atcgcccaca tcgccccctc ggcccccagc     1680

cctgcggtgc aactggcgcc tgccacaccc cccattgggc acatcactgt gcaccctgcc     1740

accctcaacc atgtggccca cctgggctcc cagctgccct tgtacccgca gcccgtggca     1800

gtgagccaca tcgcccacac cctctcgcac cagcaagtca acggcacggc cggcctgggg     1860

cccccggcta ctgtcatggc aaagccggcc gtgggggctc aggtggtgca ccacccccag     1920

ctggtgggcc agaccgtgct caaccctgtg accatggtca ccatgccctc cttcccagtc     1980

agcacactca agctggcttg aggacgaggc cactcagagg cccccagtgg ggacagggag     2040

ggggacctgt cccccactct ctcacccacc agctccacac attccagcca ggcccaggcc     2100

agccccccca cccaccccca ggcctcctag gggaaggggg tgcaaagact ctgagccaag     2160

ggagggaagg gccaccctgc tgcactagga cttggtaaga tgactctgag aaaatgcgag     2220

actctgatgg aatgtgccac ctgtccggcc cagtgccagc tccagtgccg ctcctgcttc     2280

ccctccctac cctcggaaat cagtgcgatg tggacgtcac gctccctgac ttctcccccg     2340

ccctgccccg ccttcgtgtg ctgctgctgc tattgctgtc tggtgaggtg gcccaggccc     2400

ccggctttcc tccggagcct catgttctct tcccaggcct ttggagggga aatggggaaa     2460

gcagaactga agccacttgg cccagaaagc tgcggattgg ggtgataagg ggccttgctc     2520

tgagcacagg tgacagatca taggaagtgg ctggtctgga gtcccacccg gacaggtggg     2580

gcctcagcct ggggctctct gacccggttg cagtcactgt gattcgttac cgtagatact     2640

acttaaaatg attctctacc aacaataaac caaacccagc cactgccaag cttcctgtgc     2700

cctcacccca atccctgcca ctgggctctg gacctcagga gggcaggctg aggtggggaa     2760

ggagggactt ggctgtcctt ccccttcccc gtcccctgca gcctgggtct ggatgggagg     2820

agagccactg ggcccctgtc cccagtcccc agtccccagc cctgggcttg gctcttggct     2880

tccagaaggc agcaaagagg ggcgctgtcc tgcgttcagc ccctgatctc tgacctctgc     2940

tgagtgctgg gcactgctcc aagggacagg tgggcctggc ggcctgtggg tttgggtgcc     3000

tcctgcagtt tgggagacat ggaccagcat ctggtcttgt ttccaggagc atagaagcca     3060

catcgttgag acatcaggaa ggtaaaaacc cagcggctta gccaagccct aagcctgtcc     3120

ccagaccaac cctgggacct atacagaaca gagggccaga gctagggctg ctgcttctgc     3180

tccagcccct ttgcctctgt cctcccatcc cctcaacacc ctgcttctcc cggggacgct     3240

tttgagtggg ccctgcccgg ggagctgcag agcagcagca cctttctctg agaagaggtc     3300

cttggttggg tcaaggacag ggctgagcgt ggaaggggga ggagtcaggg gctctgtgtt     3360

aggatgcggc tttctctgcc tctgggcagc ctgctttggc ctttccttgt atgtgggtgt     3420

ttattacaag tggctttgtg tcagacacgc tcggctcccc acctggacac acactcacca     3480

gtggcctttc agtgtagcgg gaggaagccg gtgtccctgg atgtgaagct cacactgatg     3540

ggctggggca ggggcctggg ccggcgaggg ggccgggggg aggggacaga gctgaggatt     3600

tcctggagtg ccctgcaggc acagaggagg tcagcaaagg tcttgaatag attttctctg     3660

gaaataaaga atccttagat gcctaaaaat tcccttcctg ttccctcctg gtcctggaca     3720

cctcccaggg gactgttcct tatttctctc tcctggtgtg ggtaaaggga cagttacaaa     3780

ccaggtcacc atcctcagag gctgagccct gtacccaccc cagcacagcc acctccgcca     3840

gaccccgtgg ctctgggaga gccagctttg ctattcccat tgtgacagcg atggcaggcc     3900

tgacccacgg ggcagttaga gcagcctcgt ggagctcgcc cctcccctca gcctgcccac     3960

ctctccctgc atcctgaggc cagtggcccc cgggcctgca cagatacctc atcatccacc     4020

cgctgcccct ccccgtccct gtcccccagc atcgggggcc tgcaaatcta gtgccgaatg     4080

actatgtcca gattggtgac gatgggtgtt gctgtttttc ttgtcgtttg tgaacgctgt     4140

gatgctgtgt gcccaagtgg gcagtcacca cccagccctt ccttgggcgt ctcccccaga     4200

gtgctgtcgg gaccacatct gtcctcaccc tgtgggaccg cctggccctc cctccctagc     4260

ccttccagcc tgggacacac acacacacac acacacacac acacgcacgc acacgcacac     4320

atcttacctc tcatgcgtgt tttacctttt gatgttcaga gtggctcact ggctgggagt     4380

ccttacctcg gggagagggg gaggttggtt ccttgggggg ccaaagaagg cagggaatgc     4440

ctggagggta actggggggc caccatgacc ccttctctct ccagaaacag ctgcttctcc     4500

ccccatccca gggtcccacc cccaaccccc agaggtggcc cttgtttaca gtgaggactc     4560

ggccactgtg tctctgtttc ctgaaatata aactgtagcg accccagact gtagagattt     4620

ttatgtgttt ggatacatct gctgtgtgga aaaaaaaaaa aactacaaaa accctaattt     4680

tgtacatact gtatttttac tattgaactg tattctagtg gctgttcatg ctccaagact     4740

ttagttaccg agacatgaat actatccatg taataagcac ttgcctggaa taaaatataa     4800

aactgaaata aacctgcact gaaacctgag atggagctgc caaaaaaaaa aaaaaaaaaa     4860

aaaaa                                                                 4865


<210>  1414
<211>  3392
<212>  DNA
<213>  homo sapiens

<400>  1414
tttctctctc tctctctctt aaagttggcg cgctctcttc acaagttcca tcactaccca       60

agaagtgagg gggcgggggg gacaggcggg aaggcattaa ttacacctaa atctgaagtt      120

tgcggcctca agtaccactt tgatggggag agcttctgaa gcttccatac aacctgccgt      180

gcctttgctg ctgccgcagt agattttcag ctcatttctt tctgctgctg cttcgcgctg      240

ctctgtcatg cctaaatcta tctcgtcact gccaaaggtg cctgaatcag ggtgaattcc      300

acgagattca ccagcggttt tgctccagtc caaggaggag gcgcgcagcc cagctcccct      360

agtctctctt cttaaatccc cctacctacg gctgccgagg ttggccgcgc gtcgggaatc      420

tccccgacag tcctggccct cccccgcccc ccgggttggt ttttcccagc tgcggaggtt      480

gggaggttgg gccaggggct ggggtgcgaa gagagtcggc gcccgcaacg cggagccggg      540

aagtcgtcgc tactctggtg gaactcagag ttggttctgg aggcggcgga cgcggaggtc      600

cctcagagga tccagcgagg ggcgccaaca agaggcgaag aggtggcacc agggcggcgg      660

caggaagagg agcgggagca ggagcgcgga gcggagcgtc ccgacccgcc gtgcgtactt      720

tctggaggga aggggcgggg gaatcggccc ctgagggaag cgcccggtgg cgagggggtt      780

agccaagttc cggctgcggc gccactccct cggttccacg agaggaaagt tttttttttc      840

cagacgcttc cgccggctcg cgccctccgg gcccagcctc ccgagccttc ggagcgggcg      900

ccgtcccagc ccagctccgg ggaaacgcga gccgcgatgc ctggggggtg ctcccggggc      960

cccgccgccg gggacgggcg tctgcggctg gcgcgactag cgctggtact cctgggctgg     1020

gtctcctcgt cttctcccac ctcctcggca tcctccttct cctcctcggc gccgttcctg     1080

gcttccgccg tgtccgccca gcccccgctg ccggaccagt gccccgcgct gtgcgagtgc     1140

tccgaggcag cgcgcacagt caagtgcgtt aaccgcaatc tgaccgaggt gcccacggac     1200

ctgcccgcct acgtgcgcaa cctcttcctt accggcaacc agctggccgt gctccctgcc     1260

ggcgccttcg cccgccggcc gccgctggcg gagctggccg cgctcaacct cagcggcagc     1320

cgcctggacg aggtgcgcgc gggcgccttc gagcatctgc ccagcctgcg ccagctcgac     1380

ctcagccaca acccactggc cgacctcagt cccttcgctt tctcgggcag caatgccagc     1440

gtctcggccc ccagtcccct tgtggaactg atcctgaacc acatcgtgcc ccctgaagat     1500

gagcggcaga accggagctt cgagggcatg gtggtggcgg ccctgctggc gggccgtgca     1560

ctgcaggggc tccgccgctt ggagctggcc agcaaccact tcctttacct gccgcgggat     1620

gtgctggccc aactgcccag cctcaggcac ctggacttaa gtaataattc gctggtgagc     1680

ctgacctacg tgtccttccg caacctgaca catctagaaa gcctccacct ggaggacaat     1740

gccctcaagg tccttcacaa tggcaccctg gctgagttgc aaggtctacc ccacattagg     1800

gttttcctgg acaacaatcc ctgggtctgc gactgccaca tggcagacat ggtgacctgg     1860

ctcaaggaaa cagaggtagt gcagggcaaa gaccggctca cctgtgcata tccggaaaaa     1920

atgaggaatc gggtcctctt ggaactcaac agtgctgacc tggactgtga cccgattctt     1980

cccccatccc tgcaaacctc ttatgtcttc ctgggtattg ttttagccct gataggcgct     2040

attttcctcc tggttttgta tttgaaccgc aaggggataa aaaagtggat gcataacatc     2100

agagatgcct gcagggatca catggaaggg tatcattaca gatatgaaat caatgcggac     2160

cccagattaa cgaacctcag ttctaactcg gatgtctgag aaatattaga ggacagacca     2220

aggacaactc tgcatgagat gtagacttaa gctttatccc tactaggctt gctccacttt     2280

catcctccac tatagataca acggactttg actaaaagca gtgaagggga tttgcttcct     2340

tgttatgtaa agtttctcgg tgtgttctgt taatgtaaga cgatgaacag ttgtgtatag     2400

tgttttaccc tcttcttttt cttggaactc ctcaacacgt atggagggat ttttcaggtt     2460

tcagcatgaa catgggcttc ttgctgtctg tctctctctc agtacagttc aaggtgtagc     2520

aagtgtaccc acacagatag cattcaacaa aagctgcctc aactttttcg agaaaaatac     2580

tttattcata aatatcagtt ttattctcat gtacctaagt tgtggagaaa ataattgcat     2640

cctataaact gcctgcagac gttagcaggc tcttcaaaat aactccatgg tgcacaggag     2700

cacctgcatc caagagcatg cttacatttt actgttctgc atattacaaa aaataacttg     2760

caacttcata acttctttga caaagtaaat tacttttttg attgcagttt atatgaaaat     2820

gtactgattt ttttttaata aactgcatcg agatccaacc gactgaattg ttaaaaaaaa     2880

aaaaaataaa gattcttaaa agaattacag tgtgtgcaag tttgctttga aaaaaggatg     2940

aagggcagga gtattcaatg gtcttggttc cgatgataat tattacttaa catagctgag     3000

aatcaaactg tagcaatgtc taatataaat agacttggga gatcgttttg aaatggtgga     3060

tccttttagt atttaaatgg agagtttgag tattcatgtg actgtatggt cccaaagtta     3120

atgctattta tgaaacagtt ttgtaagaac ataatgaagt tggtaaaagc taagcgttct     3180

gcacaataaa cagttcccag tttggggctt tttcaaggct aatgaagtta ttgttggtct     3240

agaaaaatag tatttactta ataaaactct gtttgaaatt gttctgtgga tttttagagc     3300

agaatttgaa acaaatgtaa tgcaaataaa tataaagata aagtgtctta aagacaatat     3360

tctgaaataa aagatataaa atataattta aa                                   3392


<210>  1415
<211>  1388
<212>  DNA
<213>  homo sapiens

<400>  1415
ttggtttggg ccaggtggac tggaaggggc ggaggtaacc agaagcggct agtggcggct       60

gcctgcgtcc ccaaccccct ccgcgcagcg ctcgcgacac gcgtgccagg agtgggagcg      120

agcggcgggg ccagctgcgt tctgagcctg ggcgcagctg ccatctgctc tgggaagcac      180

cagggtgtcc ccgccgccct cagctcgaag tcagccacca tggaggcgca ggcacaaggt      240

ttgttggaga ctgaaccgtt gcaaggaaca gacgaagatg cagtagccag tgctgacttc      300

tctagcatgc tctctgagga ggaaaaggaa gagttaaaag cagagttagt tcagctagaa      360

gacgaaatta caacactacg acaagttttg tcagcgaaag aaaggcatct agttgagata      420

aaacaaaaac tcggcatgaa cctgatgaat gaattaaaac agaacttcag caaaagctgg      480

catgacatgc agactaccac tgcctacaag aaaacacatg aaaccctgag tcacgcaggg      540

caaaaggcaa ctgcagcttt cagcaacgtt ggaacggcca tcagcaagaa gttcggagac      600

atgagttact ccattcgcca ttccataagt atgcctgcta tgaggaattc tcctactttc      660

aaatcatttg aggagagggt tgagacaact gtcacaagcc tcaagacgaa agtaggcggt      720

acgaacccta atggaggcag ttttgaggag gtcctcagct ccacggccca tgccagtgcc      780

cagagcttgg caggaggctc ccggcggacc aaggaggagg agctgcagtg ctaagtccag      840

ccagcgtgca gctgcatcca gaaaccggcc actacccagc ccatctctgc ctgtgcttat      900

ccagataaga agaccaaaat cccgctggga aaaacccagg ccttgacatt gttattcaaa      960

tggcccctcc agaaagttta atgatttcca tttgtatttg tgttgatgat ggaccacttg     1020

accatcacat ttcagtattc atagatgact gtcacatttt aaaatgttcc cacttgagca     1080

ggtacacaac tggtcataat tcctgtctgt gtaattcgat gtatattttt ccaaacatgt     1140

agctattgtt tgctttgatt tttgcttggc ctcctttatg atgtgcatgt ccttgaaggc     1200

tgaatgaaca gtccctttca gttcagcaga tcaacaggat ggagctcttc atgactgtct     1260

ccagcaatag gatgatttac tataaatttc atccaactac ttgtgatctc tctcacctac     1320

atcaattatg tatgttaatt tcagcaatta aaagaattga ttttaatgac aaaaaaaaaa     1380

aaaaaaaa                                                              1388


<210>  1416
<211>  2885
<212>  DNA
<213>  homo sapiens

<400>  1416
ttgtcctgag cgcggagagg gcgagctcgg gccgcgggca gggcgggagc cggcagccgg       60

caaccaaggg aggcagaaag gcacaaagat cgcaataata tccgttataa cccgctatct      120

aaccccaccc ccaacacaca cccatccatc ccaccctccg ggagaggcag ccggcgatcc      180

gctctctgcg ccctgggaaa aagccccagc catgagcaat cagtaccagg aggagggctg      240

ctccgagagg cccgagtgca aaagtaaatc tccaactttg ctctcctcct actgcatcga      300

cagcatcctg ggccggagga gcccgtgcaa aatgcggttg ctgggagccg cgcagagctt      360

gcctgctccg ctgaccagcc gcgccgaccc ggaaaaggcc gtgcaaggct cccctaagag      420

cagcagcgcc ccgttcgagg ccgagctgca cctgccgccc aagctgcggc gcctgtacgg      480

cccgggcggg ggccgcctcc ttcagggtgc ggcagcggcg gcggcggcgg cggcggcggc      540

ggcggcagcg gccgccacgg ccacggcggg tccacgcggg gaggcccctc cgccgccacc      600

gccaaccgcg cggcccgggg aacggccgga cggcgcaggg gccgccgcgg cagccgcggc      660

cgcggccgcc gcggcctggg acacgctcaa gatcagccag gcgccgcagg tgagcatcag      720

ccgcagcaag tcgtaccgcg agaacggggc gcccttcgtg ccgccgccgc ccgcgctgga      780

cgagctgggc ggcccggggg gcgtcacgca cccggaggag cgcctcggcg tggccggcgg      840

cccgggcagc gccccggctg cgggtggtgg caccggcacc gaggacgacg aggaggagct      900

gctggaggac gaagaagatg aggacgagga agaggaactg ctggaggacg acgaggagga      960

gctgctggag gacgacgccc gcgcgctgct caaggagccc cggcgctgtc ctgtggccgc     1020

cactggcgcc gtggccgcag cagctgccgc tgcagtggcc acagagggcg gggagctgtc     1080

acccaaggag gagctgctgc tgcacccgga agacgctgag ggcaaggacg gcgaggacag     1140

cgtgtgcctc tctgcgggca gcgactcgga ggaggggctg ctgaaacgca aacagaggcg     1200

ctaccgcacc acgttcacca gctaccagct ggaggaactg gagcgggcct tccagaagac     1260

gcactacccg gacgtcttca ccagggagga actggccatg aggctggact tgaccgaggc     1320

ccgagtccag gtctggttcc agaaccgtcg ggccaagtgg cgcaagcggg agaaggcagg     1380

cgcgcagacc cacccccctg ggctgccctt cccggggccg ctctccgcca cccacccgct     1440

cagcccctac ctggacgcca gccccttccc tccgcaccac ccggcgctcg actccgcttg     1500

gactgccgct gccgccgccg ccgccgccgc cttcccgagc ctacctccgc ctccgggctc     1560

ggccagcctg ccgcccagcg gggcgccgct gggcctgagc actttcctcg gagcggcagt     1620

gttccgacac ccagctttca tcagcccggc attcggcagg ctcttttcca caatggcccc     1680

cctgaccagc gcgtcgaccg cggccgcgct cctgagacag cccacacccg ccgtggaggg     1740

cgcagtggca tcgggcgccc tggccgaccc ggccacggcg gccgcagaca gacgcgcctc     1800

tagcatagcc gcgctgaggc tcaaggccaa ggagcacgcg gcgcagctca cgcagctcaa     1860

catcctgccg ggcaccagca cgggcaagga ggtgtgctaa aggctgccct ccacacccgc     1920

gccccgcgcg cgccccgaaa ggtcacctca ctcagcacca ctcaagacca aatggaaaca     1980

gaggaccagc acactcccga gacggcactg agagagcgca gccgccttca cagcagtctg     2040

gatgcgggca tggcagccct cggcgctccg ggacgtggca cctcctcggc tggctgtcca     2100

cccgcccctg cccctgcccc tgctactgcc aacctcgctc caactccaac atccactctc     2160

tcttgttctt actttcctga aaatatcggg gaggttttct cccccagacg cctgatattg     2220

aagtaaaaaa tttaaaaagc ccaacctctt cctcctgaca ccccacttag cctttctttt     2280

ctttctttct ttctttcttt ttttttttta aatagcattt tggcgctcga agttgatctc     2340

cccagcgagg gccccagcgt gaagccaggg cccgggaagc aaatgcgagc ctgtaagata     2400

gctaacagtg cacttaaagg aaaggggcgt cttgttcttg ttctcttctt tatcatacac     2460

caaccaaggt ttttatatca aaccaaaggg aaataatact ctgctagaat atggactgtt     2520

gaagtcacca aactgtgatt attgattctg tacataccat tgttattaaa aaaaaaaaaa     2580

aaagaacaga gctttgtata tttgaaatgt tataacgcaa ttgcactcag cgtggtatgg     2640

taaaagtttg tcctcccgta gattcttact gtgttgtaga tacggtaggg ttcctagaca     2700

aatatttatg tactcaagcc ctttatttaa cttattaact gtagaggctt ccgaaacctt     2760

caagataaag gcaatggtac agtacttttg tgtaatgtgt aattgttacc acttttcctt     2820

gctatctagt ggagaagtgt cacgctcaaa ataaaaaaat tatatgttta acaaaaaaaa     2880

aaaaa                                                                 2885


<210>  1417
<211>  6259
<212>  DNA
<213>  homo sapiens

<400>  1417
cccttcctgc gccgcgctcg gctcccgcgc ctcgcctggc ctggccgctg ccgcgggcga       60

gcactgtgcg ctgggcagcc ccgggcccgc gcctcccgcc cagccggcgc ttcccggtcg      120

cagttcgctt tcccacccga gagccgcgag cgcccggccg aacccgcgat ggaataatgc      180

ccagcggccc gccaggtccc ggtcgttttc tgatgtgacg gctgagacat gagatcttca      240

gcctccaggc tctccagttt ttcgtcgaga gattcactat ggaatcggat gccggaccag      300

atctctgtct cggagttcat cgccgagacc accgaggact acaactcgcc caccacgtcc      360

agcttcacca cgcggctgca caactgcagg aacaccgtca cgctgctgga ggaggctcta      420

gaccaagata gaacagccct tcagaaagtg aagaagtctg taaaagcaat atataattct      480

ggtcaagatc atgtacaaaa tgaagaaaac tatgcacaag ttcttgataa gtttgggagt      540

aattttttaa gtcgagacaa ccccgacctt ggcaccgcgt ttgtcaagtt ttctactctt      600

acaaaggaac tgtccacact gctgaaaaat ctgctccagg gtttgagcca caatgtgatc      660

ttcaccttgg attctttgtt aaaaggagac ctaaagggag tcaaaggaga tctcaagaag      720

ccatttgaca aagcctggaa agattatgag acaaagttta caaaaattga gaaagagaaa      780

agagagcacg caaaacaaca tgggatgatc cgcacagaga taacaggagc tgagattgcg      840

gaagaaatgg agaaggaaag gcgcctcttt cagctccaaa tgtgtgaata tctcattaaa      900

gttaatgaaa tcaagaccaa aaagggtgtg gatctgctgc agaatcttat aaagtattac      960

catgcacagt gcaatttctt tcaagatggc ttgaaaacag ctgataagtt gaaacagtac     1020

attgaaaaac tggctgctga tttatataat ataaaacaga cccaggatga agaaaagaaa     1080

cagctaactg cactccgaga cttaataaaa tcctctcttc aactggatca gaaagaagat     1140

tctcagagcc ggcaaggagg atacagcatg catcagctcc agggcaataa ggaatatggc     1200

agtgaaaaga aggggtacct gctaaagaaa agtgacggga tccggaaagt atggcagagg     1260

aggaagtgtt cagtcaagaa tgggattctg accatctcac atgccacatc taacaggcaa     1320

ccagccaagt tgaaccttct cacctgccaa gtaaaaccta atgccgaaga caaaaaatct     1380

tttgacctga tatcacataa tagaacatat cactttcagg cagaagatga gcaggattat     1440

gtagcatgga tatcagtatt gacaaatagc aaagaagagg ccctaaccat ggccttccgt     1500

ggagagcaga gtgcgggaga gaacagcctg gaagacctga caaaagccat tattgaggat     1560

gtccagcggc tcccagggaa tgacatttgc tgcgattgtg gctcatcaga acccacctgg     1620

ctttcaacca acttgggtat tttgacctgt atagaatgtt ctggcatcca tagggaaatg     1680

ggggttcata tttctcgcat tcagtctttg gaactagaca aattaggaac ttctgaactc     1740

ttgctggcca agaatgtagg aaacaatagt tttaatgata ttatggaagc aaatttaccc     1800

agcccctcac caaaacccac cccttcaagt gatatgactg tacgaaaaga atatatcact     1860

gcaaagtatg tagatcatag gttttcaagg aagacctgtt caacttcatc agctaaacta     1920

aatgaattgc ttgaggccat caaatccagg gatttacttg cactaattca agtctatgca     1980

gaaggggtag agctaatgga accactgctg gaacctgggc aggagcttgg ggagacagcc     2040

cttcaccttg ccgtccgaac tgcagatcag acatctctcc atttggttga cttccttgta     2100

caaaactgtg ggaacctgga taagcagacg gccctgggaa acacagttct acactactgt     2160

agtatgtaca gtaaacctga gtgtttgaag cttttgctca ggagcaagcc cactgtggat     2220

atagttaacc aggctggaga aactgcccta gacatagcaa agagactaaa agctacccag     2280

tgtgaagatc tgctttccca ggctaaatct ggaaagttca atccacacgt ccacgtagaa     2340

tatgagtgga atcttcgaca ggaggagata gatgagagcg atgatgatct ggatgacaaa     2400

ccaagcccta tcaagaaaga gcgctcaccc agacctcaga gcttctgcca ctcctccagc     2460

atctcccccc aggacaagct ggcactgcca ggattcagca ctccaaggga caaacagcgg     2520

ctctcctatg gagccttcac caaccagatc ttcgtttcca caagcacaga ctcgcccaca     2580

tcaccaacca cggaggctcc ccctctgcct cctaggaacg ccgggaaagg tccaactggc     2640

ccaccttcaa cactccctct aagcacccag acctctagtg gcagctccac cctatccaag     2700

aagaggcctc ctcccccacc acccggacac aagagaaccc tatccgaccc tcccagccca     2760

ctacctcatg ggcccccaaa caaaggcgca gttccttggg gtaacgatgg gggtccatcc     2820

tcttcaagta agactacaaa caagtttgag ggactatccc agcagtcgag caccagttct     2880

gcaaagactg cccttggccc aagagttctt cctaaactac ctcagaaagt ggcactaagg     2940

aaaacagatc atctctccct agacaaagcc accatcccgc ccgaaatctt tcagaaatca     3000

tcacagttgg cagagttgcc acaaaagcca ccacctggag acctgccccc aaagcccaca     3060

gaactggccc ccaagcccca aattggagat ttgccgccta agccaggaga actgcccccc     3120

aaaccacagc tgggggacct gccacccaaa ccccaactct cagacttacc tcccaaacca     3180

cagatgaagg acctgccccc caaaccacag ctgggagacc tgctagcaaa atcccagact     3240

ggagatgtct cacccaaggc tcagcaaccc tctgaggtca cactgaagtc acacccattg     3300

gatctatccc caaatgtgca gtccagagac gccatccaaa agcaagcatc tgaagactcc     3360

aacgacctca cgcctactct gccagagacg cccgtaccac tgcccagaaa aatcaatacg     3420

gggaaaaata aagtgaggcg agtgaagacc atttatgact gccaggcaga caacgatgac     3480

gagctcacat tcatcgaggg agaagtgatt atcgtcacag gggaagagga ccaggagtgg     3540

tggattggcc acatcgaagg acagcctgaa aggaaggggg tctttccagt gtcctttgtt     3600

catatcctgt ctgactagca aaacgcagaa ccttaagatt gtccacatcc ttcatgcaag     3660

actgctgcct tcatgtaacc ctgggcacag tgtgtatata gctgctgtta cagagtaaga     3720

aactcatgga agggccacct caggaggggg atataatgtg tgttgtaaat atcctgtggt     3780

tttctgcctt caccagtatg agggtagcct cggacccggc gcgccttact ggtttgccaa     3840

agccatcctt ggcatctagc acttacatct ctctatgctg ttctacaagc aaacaaacaa     3900

aaataggagt ataggaactg ctggctttgc aaatagaagt ggtctccagc aaccgttgaa     3960

aggcatagaa ttgactctgt tcctaacaat gcagtattct caattgtgtt actgaaaatg     4020

caacattagc aaagaggtgg gttctgtttt ccaggtgaaa cttttagctc catgacagac     4080

cagcctgtag ttatctgtgt acacagttta cagctacaaa aacctacttt ggtatttatt     4140

acagaaaagt gctcagttaa atgtaagtgt tattccttca gcaaaatatt cactgaccca     4200

aaactcttta tggcatttta caatgcacac agcctcatgc aagtttagac aagtggattt     4260

atactgtctt atgagtgccc gcccctgata tattacctca ttatgcaaaa ataacatatc     4320

tttcatgact attttgacaa aagtttaaaa cacatatgaa gttcaaattt caggaaccaa     4380

ggactgccag aaaatattag cctctacatt acgcatgcat ttagaagctt acctgaaatc     4440

tgccttttat aaaggaatag tatggataag tggaattgta cattttttaa acttgattgc     4500

cattaaagca gaaattataa ggttgcaaca atatttgttt ctaatcactg gctttctcaa     4560

gagtatggat tgacatattg tgttatgaat gcacatctct cagatgtgtt gaagcatcca     4620

ttgcatccat tttttattat tttcttagtt ttgttcttgg acaaatttaa acttttaaaa     4680

gattattcaa gatgaattta aaagtcaacc cttcacacag tttccctact gtatgtagaa     4740

tccaggtgct gaaaccaagt gtttcttttc ccatgctctt tgttaaaccc caattataga     4800

taatttttcc agtcttaagc tctgtccacc ttcaagtcaa ttcataacca agtttttgaa     4860

cgctgctatg aattgcactg tgaaaagcac tcttccctct cagttttctt ttcatcccag     4920

ccatgtttat cagatcctta agaacattgt atttcagtct tttacatcag tctgaatttt     4980

ggaaaagaat gcaatagttg tactccacag tcagtggaac tgttccctga gtccgaggct     5040

catgtgtcat tctggcacta catttgctta aattgctatt ttggcaacag cacagaaaac     5100

taatattttt aagcagagaa tcttggcaat gagtgagaga tgttaatttc acagaagcac     5160

aactcccaac ccaaccctta ggaaaagccc tcttccatcg ttacagtgct cagtgaatat     5220

taatttagtt ctgcttaagt ggttgctata caaactttga atagccacct aataaataaa     5280

ccttgcatga caaacctgca aaatatttta tcagctgtta ttggaaagtg attttaagca     5340

attgcttcct cagtgtcagg gcacatgtga atttccacac caaacagagc atgaggaacc     5400

agttgacatg ctgggttgtg actggcagct ttagcagcct cggtactgaa gccacaccag     5460

tgtccggatg gaagtctgca tctgaggttg ctcagtgtcc cggtcattca tttacacatt     5520

ttaacttgca ttaaagagct gttcttttct gtggcctaga ctcttttcac tgatctcaaa     5580

ataaactggt ttttttcaaa aaaaaaaaaa aaacaaaaac aaaaaaaaaa cacaaaagct     5640

gcatgtctaa aattacatgg agttagtgtc tattcttttt ccccttttgc agcaacttac     5700

acagcatttt taacaccttt tttttctagt ttttttgttc ggttttgttt tccatcagga     5760

atttgagttc tctctaaccc agcttactgt gggacatagg aaaactcagt agaaatacct     5820

ttggtgatct tgttgagttt aagtctgatc ttgatcttaa actcagtaag ccactatctg     5880

caattttgta cattatatag tattttgaag atatggaacc ttatgaaaaa aaaatagcaa     5940

attagttctt tttcccccag aggggaaagt tatgttctgc aaatagtgtg tgtcttattt     6000

tactgttgaa cagcaattgc tatttatttt tttattgcct agaacttcaa catgttgtat     6060

aggaatcctg tagtgccact agttaaatgc cgaattctca tctggatgtt accatcaaac     6120

atcagtacac ttgtcatttc acatgtgttt aatgtgacag tttttcagta ctgtatgtgt     6180

taatttctac tttttttaat atttaaaatt gcttttaaat aaacatattc tcagttgatc     6240

ccaaaaaaaa aaaaaaaaa                                                  6259


<210>  1418
<211>  2474
<212>  DNA
<213>  homo sapiens

<400>  1418
aaaggcgggg cgggcggctg ccaagccggc caataggcgg ctctccggct gctaagccga       60

gagggcaggg gcgccgtcag tagcaccacc gccttccaag tttccccttg tggatgcgcg      120

gccccgcggc tctgctcctc ccggcgcaga ggggccggga gaggccacag gagcggacct      180

ggcacgggat ttctgaggaa cgggagaaga ctggcgcccg acccgctctg gagggtcggt      240

gaacgatgaa gggccggcgg cggcgacgcc gagagtactg caagttcgcg ctgctgttgg      300

tgctgtacac gctggtgctg ttgctcgtcc cctccgtatt ggacggcggc cgcgacgggg      360

acaagggcgc cgagcactgc cccggcctgc agcgcagcct gggagtgtgg agcctggagg      420

cggcggcggc cggcgaacgc gagcagggag cggaggcgcg ggccgccgag gaagggggcg      480

cgaaccagtc tcctcggttc ccaagcaacc tcagcggcgc tgtcggggag gcagtgtctc      540

gcgagaagca gcacatctac gtgcatgcca cctggcgcac cggctcgtcc ttcctgggcg      600

aactctttaa ccagcacccg gacgttttct acttgtatga gcccatgtgg catctatggc      660

aggcgctgta tccgggcgac gccgagagct tgcagggcgc gctgcgcgac atgctgcgtt      720

cgctcttccg ctgcgacttc tccgtgctgc ggctgtacgc gccgccgggg gaccccgctg      780

cgcgcgcccc ggacacggcc aatcttacca cggccgccct cttccgctgg cggactaaca      840

aggtcatctg ctcgccgcca ctgtgtcctg gcgcaccccg tgcccgggcc gaggtgggcc      900

tcgtcgagga caccgcctgc gagcgcagct gcccacccgt ggcgatacgc gccctggagg      960

ccgagtgccg aaagtacccg gtggtggtca tcaaggacgt gcgcctgctc gatctgggcg     1020

tgctggtgcc cctgttgcgt gatccaggcc tcaacctgaa ggtggtgcag cttttccgcg     1080

acccgagggc ggtgcacaac tcgcgcctca agtctaggca gggactgctg cgcgagagca     1140

tccaggtgct gcgcacccgc cagaggggcg accgcttcca ccgtgtgctg ctggcgcacg     1200

gcgtgggtgc tcgccccggg ggccagtctc gcgcgctgcc cgccgcgccg cgcgccgatt     1260

tcttcctgac cggtgcgctc gaggtgatct gcgaagcctg gctgcgcgat ctgcttttcg     1320

cgcgcggcgc gcccgcctgg ctgcggcgcc gctacctgag gctgcgctat gaggacctgg     1380

tgcggcagcc acgcgcccag ctgcgccgcc tgctgcgctt ctccgggcta cgcgcgctcg     1440

cagcgctcga tgccttcgcg ctcaacatga ctcgcggcgc ggcctacggc gccgaccggc     1500

ccttccacct gtcagcgcgc gacgcccggg aggcggtgca cgcctggcgc gagcgcctga     1560

gccgagagca ggtgcgccag gtggaggccg cctgcgctcc agccatgcgt ctgctcgcct     1620

accctcgcag cggagaggag ggcgacgcgg agcagcccag ggaaggggag acgccgctgg     1680

agatggatgc cgacggcgcc acgtagcctc ccatccctgt ccccggcacg gatccgggtc     1740

agtcaccacg aacaggggca ctcggcatgc tgccccagca ctggagaagc agcgctgtgg     1800

gggcaatctg tcacactctc agagtctggg acttgacttg ctaccaacaa ctgctgtgca     1860

attctgctga gcaggaatat catgagctgt tcaataatga cggacgcatt ggttgagatg     1920

aagtttccag taaggaagtg acagtgcaat gtggatattt atggctgtaa aataggaaga     1980

gctttagttc ccaggctgaa cctgccactg ctggagccat ttcaacaagg catcctcaca     2040

acaaagaaga gatgtgattt ggtaccattt cacaccagca ggtgtctgga cgaaaacatc     2100

aatgtgaata agggccaagt gcagtcctgt cttgattaaa ttacttaata atattattaa     2160

ataataatag gtctgggcag tattgttttt aacctgactc atccagctgt ccttcaaata     2220

gctccgtctc cctctaccca gaactgattt ttaaaaagaa gtaatttttc tccctgggct     2280

gggaaaaccc taatgaactg aaacacactt ttactttaaa atttttctgt ctggcgtttt     2340

tgtaatcata ctattaaatg actctggagt catgttaatg acaggatttg ttttgtttgg     2400

atgcagttca attgcatggt ttgggtaaaa gctagcctac atacaaagga atatgaagac     2460

tgtggaagaa actg                                                       2474


<210>  1419
<211>  2115
<212>  DNA
<213>  homo sapiens

<400>  1419
agcacctacc agggtcgagc tcacacacgt gcctacgacc cgccgcggcg cctgcgcggt       60

agcatcgcgg agtcggtgct ttagtacgcc gctggcacct ttactctcgc cggccgcgcg      120

aacccgtttg agctcggtat cctagtgcac acgccttgca agcgacggcg ccatgagtct      180

gacttccagt tccagcgtac gagttgaatg gatcgcagca gttaccattg ctgctgggac      240

agctgcaatt ggttatctag cttacaaaag attttatgtt aaagatcatc gaaataaagc      300

tatgataaac cttcacatcc agaaagacaa ccccaagata gtacatgctt ttgacatgga      360

ggatttggga gataaagctg tgtactgccg ttgttggagg tccaaaaagt tcccattctg      420

tgatggggct cacacaaaac ataacgaaga gactggagac aatgtgggcc ctctgatcat      480

caagaaaaaa gaaacttaaa tggacacttt tgatgctgca aatcagcttg tcgtgaagtt      540

acctgattgt ttaattagaa tgactaccac ctctgtctga ttcaccttcg ctggattcta      600

aatgtggtat attgcaaact gcagctttca catttatggc atttgtcttg ttgaaacatc      660

gtggtgcaca tttgtttaaa caaaaaaaaa aaaaaaaagg aaaaaccaac ctgcatggcc      720

tgtgggttat tttggtcttg taaggatcca tttctttaaa atactgacat atagagttgt      780

accttatata gaatatagtt gtatcttgaa gtcaacatat taaattattc tcaaaattat      840

gtatttgcag attgtacttg taagtttcaa agaaaaatta ccatcttttc atattgacct      900

ggaaactaaa taggatgtga ttcagctaca ttaatttctt aatacaatct aggaaagacc      960

tgttgtagcc ttgattttct tgacattggt aatgacactg agaaaatatg gcttctgttt     1020

ttcaccgttt tcaatcaaaa tgattgataa atgttattct gtttaatttc ataagtcagg     1080

tcaataataa aggggtggta acttcctcat atttatcttc acagatattt aatgaagatg     1140

gatccattaa aggagccaat agtgaaaatt tagttaaagg tgatattaga tttaaattag     1200

tcatgaagaa tgtcttaaaa tctaatgttc cagaattctg gcccaaggaa tggtaagcac     1260

ttgaactgag gattttgaag gaattggaac atataatgtc aagtcttttg atcactaagc     1320

cacatatcct gacagaaata gtagtcacaa gattagatca aaggcgtggg aagatttttt     1380

tttttcccac tctagctaat caagcacatg gcttttaaat tgtatgatct ttttcttaaa     1440

agcaaaaatt tgaagacaag tgtttgttta tgtaatattc ttcaaagact ccgagcagaa     1500

acattgcatt cattgttgat tcagaaaaaa gaaaatataa aaactgaaaa taattagcaa     1560

taaaagattt aagacaaata gttcataaat atttttaaag agattaggtt tttgaatttc     1620

ataggttaga aggaaaatca tggcaaaatt tacagaaaat tgggcaaaca attgaaattg     1680

ataaagcagg taaacatcat catttatttt agtatacatg aattctcagt agtagtcaat     1740

cacaaatttc tacttgctaa aatccattta ccttgacagg aatcaaacct gacagcagca     1800

tatcctatgt aatatatgat catggctatt tttaaatatg tagttttgtg tattactgta     1860

gataaaagtt ggtaacaaaa ttgtacagtg gttttaagaa gcccatgtaa ctaacttgga     1920

catgtcttta agtcacatat tcatcataaa atctaaaatc ctacaaactg attctattag     1980

attcttaggg taaatttttt ctttgcccac ctccttcttt ttaagataag tatgcatgtc     2040

agcaaaacag agcaatcatg cttttaaaga tgaactgttt taaagaaaaa taaatgcatc     2100

aactcccaaa aaaaa                                                      2115


<210>  1420
<211>  2115
<212>  DNA
<213>  homo sapiens

<400>  1420
agcacctacc agggtcgagc tcacacacgt gcctacgacc cgccgcggcg cctgcgcggt       60

agcatcgcgg agtcggtgct ttagtacgcc gctggcacct ttactctcgc cggccgcgcg      120

aacccgtttg agctcggtat cctagtgcac acgccttgca agcgacggcg ccatgagtct      180

gacttccagt tccagcgtac gagttgaatg gatcgcagca gttaccattg ctgctgggac      240

agctgcaatt ggttatctag cttacaaaag attttatgtt aaagatcatc gaaataaagc      300

tatgataaac cttcacatcc agaaagacaa ccccaagata gtacatgctt ttgacatgga      360

ggatttggga gataaagctg tgtactgccg ttgttggagg tccaaaaagt tcccattctg      420

tgatggggct cacacaaaac ataacgaaga gactggagac aatgtgggcc ctctgatcat      480

caagaaaaaa gaaacttaaa tggacacttt tgatgctgca aatcagcttg tcgtgaagtt      540

acctgattgt ttaattagaa tgactaccac ctctgtctga ttcaccttcg ctggattcta      600

aatgtggtat attgcaaact gcagctttca catttatggc atttgtcttg ttgaaacatc      660

gtggtgcaca tttgtttaaa caaaaaaaaa aaaaaaaagg aaaaaccaac ctgcatggcc      720

tgtgggttat tttggtcttg taaggatcca tttctttaaa atactgacat atagagttgt      780

accttatata gaatatagtt gtatcttgaa gtcaacatat taaattattc tcaaaattat      840

gtatttgcag attgtacttg taagtttcaa agaaaaatta ccatcttttc atattgacct      900

ggaaactaaa taggatgtga ttcagctaca ttaatttctt aatacaatct aggaaagacc      960

tgttgtagcc ttgattttct tgacattggt aatgacactg agaaaatatg gcttctgttt     1020

ttcaccgttt tcaatcaaaa tgattgataa atgttattct gtttaatttc ataagtcagg     1080

tcaataataa aggggtggta acttcctcat atttatcttc acagatattt aatgaagatg     1140

gatccattaa aggagccaat agtgaaaatt tagttaaagg tgatattaga tttaaattag     1200

tcatgaagaa tgtcttaaaa tctaatgttc cagaattctg gcccaaggaa tggtaagcac     1260

ttgaactgag gattttgaag gaattggaac atataatgtc aagtcttttg atcactaagc     1320

cacatatcct gacagaaata gtagtcacaa gattagatca aaggcgtggg aagatttttt     1380

tttttcccac tctagctaat caagcacatg gcttttaaat tgtatgatct ttttcttaaa     1440

agcaaaaatt tgaagacaag tgtttgttta tgtaatattc ttcaaagact ccgagcagaa     1500

acattgcatt cattgttgat tcagaaaaaa gaaaatataa aaactgaaaa taattagcaa     1560

taaaagattt aagacaaata gttcataaat atttttaaag agattaggtt tttgaatttc     1620

ataggttaga aggaaaatca tggcaaaatt tacagaaaat tgggcaaaca attgaaattg     1680

ataaagcagg taaacatcat catttatttt agtatacatg aattctcagt agtagtcaat     1740

cacaaatttc tacttgctaa aatccattta ccttgacagg aatcaaacct gacagcagca     1800

tatcctatgt aatatatgat catggctatt tttaaatatg tagttttgtg tattactgta     1860

gataaaagtt ggtaacaaaa ttgtacagtg gttttaagaa gcccatgtaa ctaacttgga     1920

catgtcttta agtcacatat tcatcataaa atctaaaatc ctacaaactg attctattag     1980

attcttaggg taaatttttt ctttgcccac ctccttcttt ttaagataag tatgcatgtc     2040

agcaaaacag agcaatcatg cttttaaaga tgaactgttt taaagaaaaa taaatgcatc     2100

aactcccaaa aaaaa                                                      2115


<210>  1421
<211>  3736
<212>  DNA
<213>  homo sapiens

<400>  1421
accggccccg gcaactgcag tccaggctcc gcctccctac gcccattggc ttattcaatt       60

cacgcaggaa ccaatgggcg gagacggcag ccgcgccgtc tgacggctta gccgcggtgc      120

agactgcggc ggcggtggtc tgaggaagtt ctatcttggc gctaaagcgg agacgcatcc      180

cccgacccga ggctacgatg agcacaccgg ccgtgcccca ggacctgcag ctgcccccga      240

gtcagagggc gcagtccgca ttcaaagagc aaagaagaca aaaactcaag gaacatctgt      300

tgagaagaaa aacgcttttt gcatacaagc aggaaaatga gatgttatcc agtagagatc      360

agagagttgt gacatctgag gaccaagttc aagaagggac taaagtgctg aaacttaaaa      420

caaaaatggc tgataaagaa aacatgaaga gacctgcaga gagcaaaaat aatacagtgg      480

tggggaaaca ttgtattcct ttaaaacctt caaatgaact aaccaattca actgtagtaa      540

ttgacacaca taaacctaag gatagtaatc aaactccgca tttgttacta actgaagatg      600

atccccaaag tcaacatatg acattaagcc aggcatttca ccttaaaaac aatagtaaaa      660

agaaacaaat gactacagaa aaacaaaagc aagatgctaa catgcccaag aaacctgtgc      720

ttggatctta tcgtggccag attgttcagt ctaagattaa ttcatttaga aaacctctac      780

aagtcaaaga tgagagttct gcagcaacaa agaaactttc agccactata cctaaagcca      840

caaaacctca gcctgtaaac accagcagtg taacagtgaa aagtaataga tcctccaata      900

tgactgccac tactaaattt gtgagcacta catctcagaa cacacaactt gtgcgacctc      960

ctattagaag tcatcacagt aatacccggg acactgtgaa acaaggcatc agtagaactt     1020

ctgccaatgt tacaatccgg aaagggcctc atgaaaaaga actattacaa tcaaaaacag     1080

ctttatctag tgtcaaaacc agttcttctc aaggtataat aagaaataag actctatcaa     1140

gatccatagc atctgaagtt atagccaggc ctgcttcatt gtctaatgat aaactgatgg     1200

aaaagtcaga gcccgttgac cagcgaagac atactgcagg aaaagcaatt gttgatagta     1260

gatcagctca gcccaaagaa acctcggaag agagaaaagc tcgtctgagt gagtggaaag     1320

ctggcaaagg aagagtgcta aaaaggcccc ctaattcagt agttactcag catgagcctg     1380

caggacaaaa tgaaaaacca gttgggtctt tttggactac catggcagaa gaagatgaac     1440

aaagattatt tactgaaaaa gtaaacaaca cattttctga atgcctgaac ttgattaatg     1500

agggatgtcc aaaagaagat atactggtca cactgaatga cctgattaaa aatattccag     1560

atgccaaaaa gcttgttaag tattggatat gtcttgcact tattgaacca atcacaagtc     1620

ctattgaaaa tattattgca atctatgaga aagccattct ggcaggggct cagcctattg     1680

aagagatgcg acacacgatt gtagatattc taacaatgaa gagtcaagaa aaagctaatt     1740

taggagaaaa tatggagaag tcttgtgcaa gcaaggaaga agtcaaagaa gtcagtattg     1800

aagatacagg tgttgatgta gatccagaaa aactggaaat ggagagtaaa cttcatagaa     1860

atttgctatt tcaagattgt gaaaaagagc aagacaacaa aacaaaagat ccaacccatg     1920

atgttaaaac ccccaataca gaaacgagga caagttgctt aattaaatat aatgtgtcta     1980

ctacgccata cttgcaaagt gtgaaaaaaa aggtgcagtt tgatggaaca aattccgcat     2040

ttaaagagct gaagttttta acaccagtga gacgttctcg acgtcttcaa gagaaaactt     2100

ctaaattgcc agatatgtta aaagatcatt atccttgtgt gtcttcattg gaacagctaa     2160

cggagttggg aagagaaact gatgcttttg tatgccgccc taatgcagca ctgtgccggg     2220

tgtactatga ggctgataca acataagaga aataaagctc tgttagggaa tggggttttt     2280

attatttgtg gggtgttttg ttttgagtag ctttatattg ctcttaggtc tggagttggc     2340

catgtaccta tgtatcctaa gcattcacgg cagtgagctc ctttactaac attcatgtta     2400

tggcaagagt tgtcctctac attggaaagc taatcctacc ttgtcagttt caaccaactg     2460

agttttttct ttaagaaagg taaattttgt cagctagttt actatgttcc ttgaatataa     2520

acaggttata atactaccct gttcacttta ctaaatataa gtacagtaat gatgcataat     2580

tagaaaatga ggtattctag gtaaaatgta tgtttgcctt gacatgtttt taaaagttat     2640

gatgtacctc cctgccttta aacagaatac ttttttcttt tttttggcct ttctcagatt     2700

agtcaaaaat tctatagaat gactcacttc gaatactaag acacaggagg tttagcctgc     2760

tttcttacca aattcatgtt acccagactt gtgttctctt gcgtcccttg gactgcctgt     2820

tgattgatgg aaagtgtctg cactgacact tttcgtcagt agtctgtagt ttcgtggcct     2880

cttttgatta taactggggt caccaagaag gtttacttaa ttaaataccg catttctaag     2940

agaagatact ttgtgtaaga aaagatgcca catttagtgg tttaactttt gtaacttcac     3000

ttgatagttt ttaagcaatt agaatggagt tagggaaaga acatatcata ctgaacaaat     3060

gtcattctag tttagatagc atttctaaga taactgatac taatacttgt tttcttccct     3120

ataacataaa aaacttcact gttaagtcat gtcccttgaa acatgatagt tacatacaca     3180

gttttctctc cacacataaa taacaccact aaagttgttt tgtaaggttc caaactaata     3240

tggcatatat caactctaca gtttcaaata aatgactttt taattgtaaa agattagttg     3300

aaaaactgta tgaatgtgaa gatcacatgc ttagtcattt ttatgttcat tccactttgt     3360

atatcttttc tatttattga cttctcatgt tctagagagt aggactttta ttccgtgtac     3420

ctgatatata tacaattaaa atatctgtgt aattatgttt taatgaagtt tatttcaaca     3480

gatattttat gaaatgcagt ttaaccacag tgaatgaatt ttagctttgc ttttgaaata     3540

cattgtaaga tttgacttga ggtttttgac acttaagtac atgcttaatg atatattttc     3600

aaaagtcatc agtctactta cataaacttt acctaatttt tttcacttta acaaaaacat     3660

aactatgccc ttgttttttc atactttgac ccaaaatatg ccattttgaa ataaaattta     3720

agctttgata cactct                                                     3736


<210>  1422
<211>  2132
<212>  DNA
<213>  homo sapiens

<400>  1422
aatggggcgc cgactcggcg caggaacaag gcgggggttc ggggccggct gcagactctc       60

accgcagcgg ccaggaacgc cagccgttca cgcgttcggt cctccttggc tgactcaccg      120

ccctggccgc cgcaccatgg acgcccccag gcaggtggtc aactttgggc ctggtcccgc      180

caagctgccg cactcagtgt tgttagagat acaaaaggaa ttattagact acaaaggagt      240

tggcattagt gttcttgaaa tgagtcacag gtcatcagat tttgccaaga ttattaacaa      300

tacagagaat cttgtgcggg aattgctagc tgttccagac aactataagg tgatttttct      360

gcaaggaggt gggtgcggcc agttcagtgc tgtcccctta aacctcattg gcttgaaagc      420

aggaaggtgt gctgactatg tggtgacagg agcttggtca gctaaggccg cagaagaagc      480

caagaagttt gggactataa atatcgttca ccctaaactt gggagttata caaaaattcc      540

agatccaagc acctggaacc tcaacccaga tgcctcctac gtgtattatt gcgcaaatga      600

gacggtgcat ggtgtggagt ttgactttat acccgatgtc aagggagcag tactggtttg      660

tgacatgtcc tcaaacttcc tgtccaagcc agtggatgtt tccaagtttg gtgtgatttt      720

tgctggtgcc cagaagaatg ttggctctgc tggggtcacc gtggtgattg tccgtgatga      780

cctgctgggg tttgccctcc gagagtgccc ctcggtcctg gaatacaagg tgcaggctgg      840

aaacagctcc ttgtacaaca cgcctccatg tttcagcatc tacgtcatgg gcttggttct      900

ggagtggatt aaaaacaatg gaggtgccgc ggccatggag aagcttagct ccatcaaatc      960

tcaaacaatt tatgagatta ttgataattc tcaaggattc tacgtgtctg tgggaggcat     1020

ccgggcctct ctgtataatg ctgtcacaat tgaagacgtt cagaagctgg ccgccttcat     1080

gaaaaaattt ttggagatgc atcagctatg aacacatcct aaccaggata tactctgttc     1140

ttgaacaaca tacaaagttt aaagtaactt ggggatggct acaaaaagtt aacacagtat     1200

ttttctcaaa tgaacatgtt tattgcagat tcttcttttt tgaaagaaca acagcaaaac     1260

atccacaact ctgtaaagct ggtgggacct aatgtcacct taattctgac ttgaactgga     1320

agcattttaa gaaatcttgt tgcttttcta acaaattccc gcgtattttg cctttgctgc     1380

tactttttct agttagattt caaacttgcc tgtggactta ataatgcaag ttgcgattaa     1440

ttatttctgg agtcatggga acacacagca cagagggtag gggggccctc taggtgctga     1500

atctacacat ctgtggggtc tcctgggttc agcggctgtt gattcaaggt caacattgac     1560

cattggagga gtggtttaag agtgccaggc gaagggcaaa ctgtagatcg atctttatgc     1620

tgttattaca ggagaagtga catactttat atatgtttat attagcaagg tctgttttta     1680

ataccatata ctttatattt ctatacattt atatttctaa taatacagtt atcactgata     1740

tatgtagaca cttttagaat ttattaaatc cttgaccttg tgcattatag cattccatta     1800

gcaagagttg taccccctcc ccagtcttcg ccttcctctt tttaagctgt tttatgaaaa     1860

agacctagaa gttcttgatt catttttacc attctttcca taggtagaag agaaagttga     1920

ttggttggtt gtttttcaat tatgccatta aactaaacat ttctgttaaa ttaccctatc     1980

ctttgttctc tactgttttc tttgtaatgt atgactacga gagtgatact ttgctgaaaa     2040

gtctttcccc tattgtttat ctattgtcag tattttatgt tgaatatgta aagaacatta     2100

aagtcctaaa acatctaaaa aaaaaaaaaa aa                                   2132


<210>  1423
<211>  3329
<212>  DNA
<213>  homo sapiens

<400>  1423
ggggtcctgg cgagaagcga gccggcggcc tgaggaggcg actgactgag cagcgcaccc       60

ggggagcaag gaggcgcggt gaactgagcg gcccctgagc tgacagatac actgcgcagc      120

tggaacggcg agcgagccga cgggcgagtg aggggcgcag ccatgatcac ctcggccgct      180

ggaattattt ctcttctgga tgaagatgaa ccacagctta aggaatttgc actacacaaa      240

ttgaatgcag ttgttaatga cttctgggca gaaatttccg agtccgtaga caaaatagag      300

gttttatacg aagatgaagg tttccggagt cggcagtttg cagccttagt ggcatctaaa      360

gtattttatc acctgggggc ttttgaggag tctctgaatt atgctcttgg agcaggggac      420

ctcttcaatg tcaatgataa ctctgaatat gtggaaacta ttatagcaaa atgcattgat      480

cactacacca aacaatgtgt ggaaaatgca gatttgcctg aaggagaaaa aaaaccaatt      540

gaccagagat tggaaggcat cgtaaataaa atgttccagc gatgtctaga tgatcacaag      600

tataaacagg ctattggcat tgctctggag acacgaagac tggacgtctt tgaaaagacc      660

atactggagt cgaatgatgt cccaggaatg ttagcttata gccttaagct ctgcatgtct      720

ttaatgcaga ataaacagtt tcggaataaa gtactaagag ttctagttaa aatctacatg      780

aacttggaga aacctgattt catcaatgtt tgtcagtgct taattttctt agatgatcct      840

caggctgtga gtgatatctt agagaaactg gtaaaggaag acaacctcct gatggcatat      900

cagatttgtt ttgatttgta tgaaagtgct agccagcagt ttttgtcatc tgtaatccag      960

aatcttcgaa ctgttggcac ccctattgct tctgtgcctg gatccactaa tacgggtact     1020

gttccgggat cagagaaaga cagtgactcg atggaaacag aagaaaagac aagcagtgca     1080

tttgtaggaa agacaccaga agccagtcca gagcctaagg accagacttt gaaaatgatt     1140

aaaattttaa gtggtgaaat ggctattgag ttacatctgc agttcttaat acgaaacaat     1200

aatacagacc tcatgattct aaaaaacaca aaggatgcag tacggaattc tgtatgtcat     1260

actgcaaccg ttatagcaaa ctcttttatg cactgtggga caaccagtga ccagtttctt     1320

agagataatt tggaatggtt agccagagcc actaactggg caaaatttac tgctacagcc     1380

agtttgggtg taattcataa gggtcatgaa aaagaagcat tacagttaat ggcaacatac     1440

cttcccaagg atacttctcc aggatcagcc tatcaggaag gtggaggtct ctatgcacta     1500

ggtcttattc atgccaatca tggtggtgat ataattgact atctgcttaa tcagcttaag     1560

aacgccagca atgatatcgt tagacacggt ggcagtctgg gccttggttt ggcagccatg     1620

ggaactgcac gtcaagatgt ttatgatttg ctaaaaacaa acctttatca ggatgatgca     1680

gtaacagggg aagcagctgg cctggcccta ggtttggtta tgttgggctc taaaaatgct     1740

caggctattg aggacatggt tggttatgca caagaaactc aacatgagaa gattctgcgt     1800

ggtcttgcag ttggcatagc tttagtaatg tatgggagga tggaagaggc tgatgctctc     1860

attgaatctc tctgtcgtga caaggaccca attcttcgaa ggtctggaat gtatactgta     1920

gccatggctt attgtggctc tggtaacaac aaagcaattc gacgcctgct acatgttgct     1980

gtaagtgatg ttaatgatga tgtcaggagg gcagcagtag aatcacttgg gttcattcta     2040

ttcagaaccc ctgaacagtg cccaagtgtt gtctctttgt tgtcagagag ttacaaccct     2100

catgtgcgct acggagctgc aatggccttg gggatatgct gtgctggtac aggaaacaag     2160

gaagccatta atttgctaga accaatgaca aacgaccccg tgaactacgt gaggcaaggg     2220

gcactcatag cttcagctct catcatgatc cagcagactg aaatcacttg tccaaaggtg     2280

aatcagttca gacagctgta ttccaaagtc atcaatgata agcatgatga tgtcatggcc     2340

aagtttggcg ctattctggc ccagggcata ctggatgcag gtggtcataa tgtcacaatc     2400

tccttgcagt ccaggactgg gcatactcat atgccttctg tggttggcgt ccttgtattt     2460

acccagtttt ggttctggtt tcctctttca cacttcctgt cattggctta tacccctacc     2520

tgtgtcattg gccttaacaa ggacttaaag atgccgaaag ttcagtataa atcgaactgt     2580

aaaccatcca catttgcata tcctgcccct ctggaagtac caaaagaaaa agaaaaggaa     2640

aaggtttcta ctgctgtatt atctataact gccaaggcta aaaagaagga aaaagaaaag     2700

gaaaaaaagg aggaggagaa aatggaagtg gatgaggcag agaaaaagga ggaaaaagag     2760

aagaaaaaag aacctgagcc aaacttccag ttattggata acccagcccg agttatgcct     2820

gcccagctta aggtcctaac catgccggag acctgtagat accagccttt caaaccactc     2880

tctattggag gcatcatcat tctgaaggat accagtgaag acattgagga gctggtggaa     2940

cctgtggcag cacatggccc aaaaatcgag gaggaggaac aagagccaga acccccagaa     3000

ccatttgagt atattgatga ttaagggcca gaggatctca cttgcttatc tgaagaagat     3060

tgtccaggct catattggga atgcttatga ggaaattcat gccgagacct gctattcaat     3120

gcatgtatcg ttgcctctgc actgacctga agaaccctgt ctccaagtct ttggttgaag     3180

agaagatata tgactgttga gtgtgctctt tcacagaact tggttttcaa ataaatataa     3240

gatctccaga tggacaagac atttgttttt cagcctgggt ttttaataaa tgtatctaat     3300

cctccccaca ccatgaaatg cctaaaaaa                                       3329


<210>  1424
<211>  2965
<212>  DNA
<213>  homo sapiens

<400>  1424
ggatgaggcc tcgccctcgc ctctttagta ggtcgggtga gtgtagtgtg cagggaagag       60

acgcgtcagc gccagggcca ggcccgcccg ggggcagccc ggcagccgaa tcttgggcta      120

ctctgtccca acagccggag cagatcagac cgaccggccc tgcccgctcg gtcccgcgcc      180

ctccagaccc tacggtctcc gtttctaggg gcacatggtt agcggcaggc gcccacagcc      240

aatccacttt gccagcctgc cccttcctct gccaagagca gcttcttcag ccgcgctcca      300

gttccgcaga cgcctgcccc accctgctct tcccttccag ggaagacgga tcacgcggcc      360

aagaacgaga ctcgcaaact gggcatttct ccgagccggg ctagagcaag tagcgagact      420

ccgcgtgaga gtgggaaaga gccttaacag gcaaccatgt tgcccagtgg gttttctgtg      480

cctttgggtg cggaccaatg aggcgcgtgg ggcgggactt ccgcttcgcc taggtgttgt      540

cgtccctgct agtactccgg gctgtggggg tcggtgcgga tattcagtca tgaaatcagg      600

gtagggactt ctcccgcagc gacgcggctg gcaagactgt ttgtgttgcg ggggccggac      660

ttcaagagag aaagagagag tgggcagaca tcgaagccaa acagcagtat cccggaagca      720

ctcatgcaac tttggtggcg gccactcagt tttctctgcc agtgtctggt gattttacaa      780

cgagatgctg ctctccatag ggatgctcat gctgtcagcc acacaagtct acaccatctt      840

gactgtccag ctctttgcat tcttaaacct actgcctgta gaagcagaca ttttagcata      900

taactttgaa aatgcatctc agacatttga tgacctccct gcaagatttg gttatagact      960

tccagctgaa ggtttaaagg gttttttgat taactcaaaa ccagagaatg cctgtgaacc     1020

catagtgcct ccaccagtaa aagacaattc atctggcact ttcatcgtgt taattagaag     1080

acttgattgt aattttgata taaaggtttt aaatgcacag agagcaggat acaaggcagc     1140

catagttcac aatgttgatt ctgatgacct cattagcatg ggatccaacg acattgaggt     1200

actaaagaaa attgacattc catctgtctt tattggtgaa tcatcagcta attctctgaa     1260

agatgaattc acatatgaaa aagggggcca ccttatctta gttccagaat ttagtcttcc     1320

tttggaatac tacctaattc ccttccttat catagtgggc atctgtctca tcttgatagt     1380

cattttcatg atcacaaaat ttgtccagga tagacataga gctagaagaa acagacttcg     1440

taaagatcaa cttaagaaac ttcctgtaca taaattcaag aaaggagatg agtatgatgt     1500

atgtgccatt tgtttggatg agtatgaaga tggagacaaa ctcagaatcc ttccctgttc     1560

ccatgcttat cactgcaagt gtgtagaccc ttggctaact aaaaccaaaa aaacctgtcc     1620

agtgtgcaag caaaaagttg ttccttctca aggcgattca gactctgaca cagacagtag     1680

tcaagaagaa aatgaagtga cagaacatac ccctttactg agacctttag cttctgtcag     1740

tgcccagtca tttggggctt tatcggaatc ccgctcacat cagaacatga cagaatcttc     1800

agactatgag gaagacgaca atgaagatac tgacagtagt gatgcagaaa atgaaattaa     1860

tgaacatgat gtcgtggtcc agttgcagcc taatggtgaa cgggattaca acatagcaaa     1920

tactgtttga ctttcagaag atgattggtt tatttccctt taaaatgatt aggtatatac     1980

tgtaatttga ttttttgctc ccttcaaaga tttctgtaga aataacttat tttttagtat     2040

tctacagttt aatcaaatta ctgaaacagg acttttgatc tggtatttat ctgccaagaa     2100

tatacttcat tcactaataa tagactggtg ctgtaactca agcatcaatt cagctcttct     2160

tttggaatga aagtatagcc aaaacataaa aaaaaaaaaa tcctcagtat agcttgcaat     2220

taagacctag atcacagtat ttaagtgttt tgcgttttat acatgaggtc agtgctacag     2280

ccacctagca tgaactaacc cagcttccac ctccataaag ttacctagag ttgttgagtt     2340

ggaatatgtt ctggcattta cctgacctgc caatcattag ggagaggcaa caaggtaatt     2400

cagcctttcc tcctatcagc acaaagaaac tcaaagctgt tttttccctt tctgttccaa     2460

agcagtctta tcctgacagg agcggtctat actagtgcag atttcaacac ttttttttaa     2520

cgttttaatt actatagtgt tatgtagaga tttgattgag cagctaatgt ttctgaactt     2580

tacttactaa ttttcagtgt ccttaagggt tctgtagtgt tatcaaagca aaaagaaaat     2640

gctgcataaa aataccaaac ttcagcaact gttaatactc agatcatata cctcttaata     2700

aatagcatct tatgctaatt agccctgcta aactatgtac agaggaaact gttcaagtat     2760

tggatttgaa agtaagtgac ttatgtttaa cagaactaat gatgtattga aacactgtat     2820

tatgaaaagc taaattatac atcattgtaa ctatgtagaa agtgtagact aatgtataat     2880

caaaatgcta aggattttta tatggccttg tatgagggga gtttgaatgt taataaacat     2940

gttttccact ttaagatcca gtaaa                                           2965


<210>  1425
<211>  2863
<212>  DNA
<213>  homo sapiens

<400>  1425
ggatgaggcc tcgccctcgc ctctttagta ggtcgggtga gtgtagtgtg cagggaagag       60

acgcgtcagc gccagggcca ggcccgcccg ggggcagccc ggcagccgaa tcttgggcta      120

ctctgtccca acagccggag cagatcagac cgaccggccc tgcccgctcg gtcccgcgcc      180

ctccagaccc tacggtctcc gtttctaggg gcacatggtt agcggcaggc gcccacagcc      240

aatccacttt gccagcctgc cccttcctct gccaagagca gcttcttcag ccgcgctcca      300

gttccgcaga cgcctgcccc accctgctct tcccttccag ggaagacgga tcacgcggcc      360

aagaacgaga ctcgcaaact gggcatttct ccgagccggg ctagagcaag tagcgagact      420

ccgcgtgaga gtgggaaaga gccttaacag gcaaccatgt tgcccagtgg gttttctgtg      480

cctttgggtg cggaccaatg aggcgcgtgg ggcgggactt ccgcttcgcc taggtgttgt      540

cgtccctgct agtactccgg gctgtggggg tcggtgcgga tattcagtca tgaaatcagg      600

gtagggactt ctcccgcagc gacgcggctg gcaagactgt ttgtgttgcg ggggccggac      660

ttcaaggtga ttttacaacg agatgctgct ctccataggg atgctcatgc tgtcagccac      720

acaagtctac accatcttga ctgtccagct ctttgcattc ttaaacctac tgcctgtaga      780

agcagacatt ttagcatata actttgaaaa tgcatctcag acatttgatg acctccctgc      840

aagatttggt tatagacttc cagctgaagg tttaaagggt tttttgatta actcaaaacc      900

agagaatgcc tgtgaaccca tagtgcctcc accagtaaaa gacaattcat ctggcacttt      960

catcgtgtta attagaagac ttgattgtaa ttttgatata aaggttttaa atgcacagag     1020

agcaggatac aaggcagcca tagttcacaa tgttgattct gatgacctca ttagcatggg     1080

atccaacgac attgaggtac taaagaaaat tgacattcca tctgtcttta ttggtgaatc     1140

atcagctaat tctctgaaag atgaattcac atatgaaaaa gggggccacc ttatcttagt     1200

tccagaattt agtcttcctt tggaatacta cctaattccc ttccttatca tagtgggcat     1260

ctgtctcatc ttgatagtca ttttcatgat cacaaaattt gtccaggata gacatagagc     1320

tagaagaaac agacttcgta aagatcaact taagaaactt cctgtacata aattcaagaa     1380

aggagatgag tatgatgtat gtgccatttg tttggatgag tatgaagatg gagacaaact     1440

cagaatcctt ccctgttccc atgcttatca ctgcaagtgt gtagaccctt ggctaactaa     1500

aaccaaaaaa acctgtccag tgtgcaagca aaaagttgtt ccttctcaag gcgattcaga     1560

ctctgacaca gacagtagtc aagaagaaaa tgaagtgaca gaacataccc ctttactgag     1620

acctttagct tctgtcagtg cccagtcatt tggggcttta tcggaatccc gctcacatca     1680

gaacatgaca gaatcttcag actatgagga agacgacaat gaagatactg acagtagtga     1740

tgcagaaaat gaaattaatg aacatgatgt cgtggtccag ttgcagccta atggtgaacg     1800

ggattacaac atagcaaata ctgtttgact ttcagaagat gattggttta tttcccttta     1860

aaatgattag gtatatactg taatttgatt ttttgctccc ttcaaagatt tctgtagaaa     1920

taacttattt tttagtattc tacagtttaa tcaaattact gaaacaggac ttttgatctg     1980

gtatttatct gccaagaata tacttcattc actaataata gactggtgct gtaactcaag     2040

catcaattca gctcttcttt tggaatgaaa gtatagccaa aacataaaaa aaaaaaaatc     2100

ctcagtatag cttgcaatta agacctagat cacagtattt aagtgttttg cgttttatac     2160

atgaggtcag tgctacagcc acctagcatg aactaaccca gcttccacct ccataaagtt     2220

acctagagtt gttgagttgg aatatgttct ggcatttacc tgacctgcca atcattaggg     2280

agaggcaaca aggtaattca gcctttcctc ctatcagcac aaagaaactc aaagctgttt     2340

tttccctttc tgttccaaag cagtcttatc ctgacaggag cggtctatac tagtgcagat     2400

ttcaacactt ttttttaacg ttttaattac tatagtgtta tgtagagatt tgattgagca     2460

gctaatgttt ctgaacttta cttactaatt ttcagtgtcc ttaagggttc tgtagtgtta     2520

tcaaagcaaa aagaaaatgc tgcataaaaa taccaaactt cagcaactgt taatactcag     2580

atcatatacc tcttaataaa tagcatctta tgctaattag ccctgctaaa ctatgtacag     2640

aggaaactgt tcaagtattg gatttgaaag taagtgactt atgtttaaca gaactaatga     2700

tgtattgaaa cactgtatta tgaaaagcta aattatacat cattgtaact atgtagaaag     2760

tgtagactaa tgtataatca aaatgctaag gatttttata tggccttgta tgaggggagt     2820

ttgaatgtta ataaacatgt tttccacttt aagatccagt aaa                       2863


<210>  1426
<211>  2965
<212>  DNA
<213>  homo sapiens

<400>  1426
ggatgaggcc tcgccctcgc ctctttagta ggtcgggtga gtgtagtgtg cagggaagag       60

acgcgtcagc gccagggcca ggcccgcccg ggggcagccc ggcagccgaa tcttgggcta      120

ctctgtccca acagccggag cagatcagac cgaccggccc tgcccgctcg gtcccgcgcc      180

ctccagaccc tacggtctcc gtttctaggg gcacatggtt agcggcaggc gcccacagcc      240

aatccacttt gccagcctgc cccttcctct gccaagagca gcttcttcag ccgcgctcca      300

gttccgcaga cgcctgcccc accctgctct tcccttccag ggaagacgga tcacgcggcc      360

aagaacgaga ctcgcaaact gggcatttct ccgagccggg ctagagcaag tagcgagact      420

ccgcgtgaga gtgggaaaga gccttaacag gcaaccatgt tgcccagtgg gttttctgtg      480

cctttgggtg cggaccaatg aggcgcgtgg ggcgggactt ccgcttcgcc taggtgttgt      540

cgtccctgct agtactccgg gctgtggggg tcggtgcgga tattcagtca tgaaatcagg      600

gtagggactt ctcccgcagc gacgcggctg gcaagactgt ttgtgttgcg ggggccggac      660

ttcaagagag aaagagagag tgggcagaca tcgaagccaa acagcagtat cccggaagca      720

ctcatgcaac tttggtggcg gccactcagt tttctctgcc agtgtctggt gattttacaa      780

cgagatgctg ctctccatag ggatgctcat gctgtcagcc acacaagtct acaccatctt      840

gactgtccag ctctttgcat tcttaaacct actgcctgta gaagcagaca ttttagcata      900

taactttgaa aatgcatctc agacatttga tgacctccct gcaagatttg gttatagact      960

tccagctgaa ggtttaaagg gttttttgat taactcaaaa ccagagaatg cctgtgaacc     1020

catagtgcct ccaccagtaa aagacaattc atctggcact ttcatcgtgt taattagaag     1080

acttgattgt aattttgata taaaggtttt aaatgcacag agagcaggat acaaggcagc     1140

catagttcac aatgttgatt ctgatgacct cattagcatg ggatccaacg acattgaggt     1200

actaaagaaa attgacattc catctgtctt tattggtgaa tcatcagcta attctctgaa     1260

agatgaattc acatatgaaa aagggggcca ccttatctta gttccagaat ttagtcttcc     1320

tttggaatac tacctaattc ccttccttat catagtgggc atctgtctca tcttgatagt     1380

cattttcatg atcacaaaat ttgtccagga tagacataga gctagaagaa acagacttcg     1440

taaagatcaa cttaagaaac ttcctgtaca taaattcaag aaaggagatg agtatgatgt     1500

atgtgccatt tgtttggatg agtatgaaga tggagacaaa ctcagaatcc ttccctgttc     1560

ccatgcttat cactgcaagt gtgtagaccc ttggctaact aaaaccaaaa aaacctgtcc     1620

agtgtgcaag caaaaagttg ttccttctca aggcgattca gactctgaca cagacagtag     1680

tcaagaagaa aatgaagtga cagaacatac ccctttactg agacctttag cttctgtcag     1740

tgcccagtca tttggggctt tatcggaatc ccgctcacat cagaacatga cagaatcttc     1800

agactatgag gaagacgaca atgaagatac tgacagtagt gatgcagaaa atgaaattaa     1860

tgaacatgat gtcgtggtcc agttgcagcc taatggtgaa cgggattaca acatagcaaa     1920

tactgtttga ctttcagaag atgattggtt tatttccctt taaaatgatt aggtatatac     1980

tgtaatttga ttttttgctc ccttcaaaga tttctgtaga aataacttat tttttagtat     2040

tctacagttt aatcaaatta ctgaaacagg acttttgatc tggtatttat ctgccaagaa     2100

tatacttcat tcactaataa tagactggtg ctgtaactca agcatcaatt cagctcttct     2160

tttggaatga aagtatagcc aaaacataaa aaaaaaaaaa tcctcagtat agcttgcaat     2220

taagacctag atcacagtat ttaagtgttt tgcgttttat acatgaggtc agtgctacag     2280

ccacctagca tgaactaacc cagcttccac ctccataaag ttacctagag ttgttgagtt     2340

ggaatatgtt ctggcattta cctgacctgc caatcattag ggagaggcaa caaggtaatt     2400

cagcctttcc tcctatcagc acaaagaaac tcaaagctgt tttttccctt tctgttccaa     2460

agcagtctta tcctgacagg agcggtctat actagtgcag atttcaacac ttttttttaa     2520

cgttttaatt actatagtgt tatgtagaga tttgattgag cagctaatgt ttctgaactt     2580

tacttactaa ttttcagtgt ccttaagggt tctgtagtgt tatcaaagca aaaagaaaat     2640

gctgcataaa aataccaaac ttcagcaact gttaatactc agatcatata cctcttaata     2700

aatagcatct tatgctaatt agccctgcta aactatgtac agaggaaact gttcaagtat     2760

tggatttgaa agtaagtgac ttatgtttaa cagaactaat gatgtattga aacactgtat     2820

tatgaaaagc taaattatac atcattgtaa ctatgtagaa agtgtagact aatgtataat     2880

caaaatgcta aggattttta tatggccttg tatgagggga gtttgaatgt taataaacat     2940

gttttccact ttaagatcca gtaaa                                           2965


<210>  1427
<211>  3422
<212>  DNA
<213>  homo sapiens

<400>  1427
gacgcagggt cggcggctca gcgccgtaga gacaaagccg cccgcccgcc agcccgctag       60

ctcctcgcgc gagctcctcc tccacgggaa cctccctccc ctcccaggcg ccgccgcagc      120

cggagcggct cccgggccct gggccgccgc cggccaggaa gaaatacttg tgttggctgc      180

atttccaggg atgctaccag agctcaaggc tgtcacctgg tcttgcccag aagagccgtt      240

cttagaggca ggacttgatg aaggctttcc tgctgatgga ataggtttgc tagagctggc      300

cttggaatta gaacccttca tgtggccttt ataaatatgc gtttgagaca gagttatatg      360

cagaagttga aaatgcctgg aagatttctg gtttctttca ctacttatcc tgcctttttg      420

catcgctgcc agatttggat gatatgatat tcagaggggc accttaatca aagccattct      480

tcaacaagac ccacctggca taagattgca cacataattc aagatggcca gtcaacctcc      540

tgaagacact gcggagtctc aggcctctga tgagctggag tgcaaaatct gttacaatcg      600

atacaatctg aaacagagga aacccaaagt gctggagtgt tgtcataggg tttgtgccaa      660

atgcctctac aagatcatag actttgggga ctccccacaa ggtgtcattg tctgtccttt      720

ctgcaggttt gagacgtgcc tgccagatga tgaagttagt agcctgcccg atgacaacaa      780

catccttgta aacttgactt gtggaggcaa agggaagaag tgcctgccag agaaccctac      840

tgagctgctg ctcaccccca agaggctggc ctctctggtc agtccttctc acacgtcctc      900

caactgcctg gtcataacca tcatggaggt gcagagagag agctccccgt ccctgagctc      960

cactcctgtg gtagaatttt ataggcctgc gagtttcgac tctgtcacca ctgtgtcaca     1020

caactggact gtgtggaact gcacgtccct gctgtttcag acatccatcc gggtgttagt     1080

gtggttgcta ggtttgctct acttcagctc cttaccctta ggaatctact tactggtgtc     1140

taagaaagtc acccttgggg tcgtctttgt cagcctggtc ccttcgagcc tcgttattct     1200

tatggtgtat ggtttttgcc agtgtgtttg tcatgaattt ctagactgta tggcacctcc     1260

ttcttaactg atatgcaaaa taagaaattg gacacacatt gccctgtttg agtgtgaagt     1320

tagataattt ataatttatt ttcttttatg ttctttatga ttagtatcca tgacattaac     1380

aaaacccttg gccacatgtt gacttgattg gttttcctgt aggctggaag taaaaatgtt     1440

catttctact taggggttag caaaattgta taagctcaca cttcatggag cactgacagc     1500

agtgagtctt cccagagaaa ggacagggtt tctctcagca ctgccagaca gacggcaggg     1560

gtgtggtgtg ttatactata gggagagcat ggatccctcc tttcgtattc atggatgttc     1620

tatgatggca gttggacaca agaggaaagt tgctctgaga cacaaagtgt gtactccttt     1680

cccaccccat acccctggta ttggaacacc ctagaattgt cttcaggtgt tttctctctt     1740

aagtcactct ctgtggtcgg cgatcccatt gagatacttg tttcctctgc ccattctccc     1800

ttgccaagag gaaactcggt tccattccct tgggtagttt caactgaata ccagttttgc     1860

cacattacta aggagaatga aaagcactga ggaatttgca tcacagtcag cttcatggca     1920

gaatgtggcc atttgtcctt gagacacact ctttcctcca tgtctgtttt cctctctcct     1980

cagtcttatc tgagaagaat ggaggagaag gaacttctca tacagcggtt attattgatg     2040

aaaaccttca tttgagtctt tccttataac atcttagttt tggttttttt aaaccacatt     2100

gcccaatcag cctcacccct tgtcctgaaa aggttccatt taaattagtt gctataaatt     2160

catcaatact ttttttccct attatatttt tggttctatt aggatttact taactgaatc     2220

ttataacaat tcgaggtgaa ctgtggcaat gaaaaccaga aacagttaat gagatgcttc     2280

agctcacagt ttgaagtgct gagaacctaa gtattttgct gtacggtact gagctgtacc     2340

aaaatatgat ggtttaggtt tatgtgcaag actttgtgtt gtagtctaga caaaggggtg     2400

ggcaagagac atgcaaagct gaagccctgc ttgaaaagac ccttcaagga agtaaaatgg     2460

caggggcaga gtgcagctta acatgttgct atccctgttg tttttgagtt ggttttggaa     2520

tggattcaag ttcttacaca atttattttg aatacaagca taatctaggt gatttgagtt     2580

aatgaacttc ttttcatgat gtagggaaag ttgaatgtat atatttctaa gaagaatttg     2640

tttagcagat tacaagttgg caaaatagac tgttcacaga aactaggcaa aaatttaaaa     2700

aaacattcta gtctctaaaa cccattacta atgattaaca ttaaaatatt tgtaactctt     2760

agaaaggggg cattactaag acgactttaa cttgttatga aatctttgtt gtgtgatgca     2820

ggtacagtgc gcccattcca actggaatag cagtttgatt ttaattgtaa aactaaactt     2880

cgggaatatg tatgcccaaa gtaagtagga tgagaatagt atacatggga tatggtccaa     2940

tgaatttaag ccccaagata cagctaaata catttatgat ttcataaaat ctagtttaga     3000

tagcattgtg atgcaatttc cagaaatcca tttgtgttta gagtaaatac catgtttaga     3060

agatgttttg tggtttggat ttatatattt gtaaggtttt tttaaaaaaa tgttcgtttt     3120

gtttgaaatg taacattgag taaattggtg agttatataa tgagatttct agaaagctct     3180

ggacatgggt acgatgtgtt ttgcttctct gtataatgtc tacagtgata aacttgtgtc     3240

tccgtgtatt gtggcagtct ttttttctag ttaatttggc tttagagagc aatctttgta     3300

tgacaccaga aaactcttca tgctattgaa tgataaaaag ataatgcttt aatattttat     3360

tcactgtgat actattttgt ttgtctatta aattgttatt atttccaaat ttaaaaaaaa     3420

aa                                                                    3422


<210>  1428
<211>  3288
<212>  DNA
<213>  homo sapiens

<400>  1428
cgagtcttct catcccggga cgcaaacctc gaaacagctg ccggctggtc ccggccgagg       60

ccggcgcagg gagggaggag ccgcccgggc tgtgggggcg ccgcgagctg ggccggcctc      120

ggtgtgcccg cgccgccagc ccgctccaga cgcgccacct gggcgctcca agaagaggcc      180

gaagtttgcc gcggccgtga gttggagctc gcgccgggcc gctgcgccgg gagctccggg      240

ggcttccctc gcttcccggt attgtttgca aactttgctg ctctccgccg cggcccccaa      300

ctcggcggac gccgggcgcg gagagccgag ccgggggcgc tgtgcgcagc gctcgggcca      360

ggccgggcgg gcatgggcgg gggcccgagc aggggtggag agccggggcc agcagcagcc      420

cgtgcccggg agcggcggcg ctgaggggcg cggagctccc cgcgaggaca cgtccaacgc      480

cagcatgcag cgcccgggcc cccgcctgtg gctggtcctg caggtgatgg gctcgtgcgc      540

cgccatcagc tccatggaca tggagcgccc gggcgacggc aaatgccagc ccatcgagat      600

cccgatgtgc aaggacatcg gctacaacat gactcgtatg cccaacctga tgggccacga      660

gaaccagcgc gaggcagcca tccagttgca cgagttcgcg ccgctggtgg agtacggctg      720

ccacggccac ctccgcttct tcctgtgctc gctgtacgcg ccgatgtgca ccgagcaggt      780

ctctaccccc atccccgcct gccgggtcat gtgcgagcag gcccggctca agtgctcccc      840

gattatggag cagttcaact tcaagtggcc cgactccctg gactgccgga aactccccaa      900

caagaacgac cccaactacc tgtgcatgga ggcgcccaac aacggctcgg acgagcccac      960

ccggggctcg ggcctgttcc cgccgctgtt ccggccgcag cggccccaca gcgcgcagga     1020

gcacccgctg aaggacgggg gccccgggcg cggcggctgc gacaacccgg gcaagttcca     1080

ccacgtggag aagagcgcgt cgtgcgcgcc gctctgcacg cccggcgtgg acgtgtactg     1140

gagccgcgag gacaagcgct tcgcagtggt ctggctggcc atctgggcgg tgctgtgctt     1200

cttctccagc gccttcaccg tgctcacctt cctcatcgac ccggcccgct tccgctaccc     1260

cgagcgcccc atcatcttcc tctccatgtg ctactgcgtc tactccgtgg gctacctcat     1320

ccgcctcttc gccggcgccg agagcatcgc ctgcgaccgg gacagcggcc agctctatgt     1380

catccaggag ggactggaga gcaccggctg cacgctggtc ttcctggtcc tctactactt     1440

cggcatggcc agctcgctgt ggtgggtggt cctcacgctc acctggttcc tggccgccgg     1500

caagaagtgg ggccacgagg ccatcgaagc caacagcagc tacttccacc tggcagcctg     1560

ggccatcccg gcggtgaaga ccatcctgat cctggtcatg cgcagggtgg cgggggacga     1620

gctcaccggg gtctgctacg tgggcagcat ggacgtcaac gcgctcaccg gcttcgtgct     1680

cattcccctg gcctgctacc tggtcatcgg cacgtccttc atcctctcgg gcttcgtggc     1740

cctgttccac atccggaggg tgatgaagac gggcggcgag aacacggaca agctggagaa     1800

gctcatggtg cgtatcgggc tcttctctgt gctgtacacc gtgccggcca cctgtgtgat     1860

cgcctgctac ttttacgaac gcctcaacat ggattactgg aagatcctgg cggcgcagca     1920

caagtgcaaa atgaacaacc agactaaaac gctggactgc ctgatggccg cctccatccc     1980

cgccgtggag atcttcatgg tgaagatctt tatgctgctg gtggtgggga tcaccagcgg     2040

gatgtggatt tggacctcca agactctgca gtcctggcag caggtgtgca gccgtaggtt     2100

aaagaagaag agccggagaa aaccggccag cgtgatcacc agcggtggga tttacaaaaa     2160

agcccagcat ccccagaaaa ctcaccacgg gaaatatgag atccctgccc agtcgcccac     2220

ctgcgtgtga acagggctgg agggaagggc acaggggcgc ccggagctaa gatgtggtgc     2280

ttttcttggt tgtgtttttc tttcttcttc ttcttttttt ttttttataa aagcaaaaga     2340

gaaatacata aaaaagtgtt taccctgaaa ttcaggatgc tgtgatacac tgaaaggaaa     2400

aatgtactta aagggttttg ttttgttttg gttttccagc gaagggaagc tcctccagtg     2460

aagtagcctc ttgtgtaact aatttgtggt aaagtagttg attcagccct cagaagaaaa     2520

cttttgttta gagccctccc taaatataca tctgtgtatt tgagttggct ttgctaccca     2580

tttacaaata agaggacaga taactgcttt gcaaattcaa gagcctcccc tgggttaaca     2640

aatgagccat ccccagggcc cacccccagg aaggccacag tgctgggcgg catccctgca     2700

gaggaaagac aggacccggg gcccgcctca caccccagtg gatttggagt tgcttaaaat     2760

agactccggc cttcaccaat agtctctctg caagacagaa acctccatca aacctcacat     2820

ttgtgaactc aaacgatgtg caatacattt ttttctcttt ccttgaaaat aaaaagagaa     2880

acaagtattt tgctatatat aaagacaaca aaagaaatct cctaacaaaa gaactaagag     2940

gcccagccct cagaaaccct tcagtgctac attttgtggc tttttaatgg aaaccaagcc     3000

aatgttatag acgtttggac tgatttgtgg aaaggagggg ggaagaggga gaaggatcat     3060

tcaaaagtta cccaaagggc ttattgactc tttctattgt taaacaaatg atttccacaa     3120

acagatcagg aagcactagg ttggcagaga cactttgtct agtgtattct cttcacagtg     3180

ccaggaaaga gtggtttctg cgtgtgtata tttgtaatat atgatatttt tcatgctcca     3240

ctattttatt aaaaataaaa tatgttcttt agtttgctgc taaaaaaa                  3288


<210>  1429
<211>  3288
<212>  DNA
<213>  homo sapiens

<400>  1429
cgagtcttct catcccggga cgcaaacctc gaaacagctg ccggctggtc ccggccgagg       60

ccggcgcagg gagggaggag ccgcccgggc tgtgggggcg ccgcgagctg ggccggcctc      120

ggtgtgcccg cgccgccagc ccgctccaga cgcgccacct gggcgctcca agaagaggcc      180

gaagtttgcc gcggccgtga gttggagctc gcgccgggcc gctgcgccgg gagctccggg      240

ggcttccctc gcttcccggt attgtttgca aactttgctg ctctccgccg cggcccccaa      300

ctcggcggac gccgggcgcg gagagccgag ccgggggcgc tgtgcgcagc gctcgggcca      360

ggccgggcgg gcatgggcgg gggcccgagc aggggtggag agccggggcc agcagcagcc      420

cgtgcccggg agcggcggcg ctgaggggcg cggagctccc cgcgaggaca cgtccaacgc      480

cagcatgcag cgcccgggcc cccgcctgtg gctggtcctg caggtgatgg gctcgtgcgc      540

cgccatcagc tccatggaca tggagcgccc gggcgacggc aaatgccagc ccatcgagat      600

cccgatgtgc aaggacatcg gctacaacat gactcgtatg cccaacctga tgggccacga      660

gaaccagcgc gaggcagcca tccagttgca cgagttcgcg ccgctggtgg agtacggctg      720

ccacggccac ctccgcttct tcctgtgctc gctgtacgcg ccgatgtgca ccgagcaggt      780

ctctaccccc atccccgcct gccgggtcat gtgcgagcag gcccggctca agtgctcccc      840

gattatggag cagttcaact tcaagtggcc cgactccctg gactgccgga aactccccaa      900

caagaacgac cccaactacc tgtgcatgga ggcgcccaac aacggctcgg acgagcccac      960

ccggggctcg ggcctgttcc cgccgctgtt ccggccgcag cggccccaca gcgcgcagga     1020

gcacccgctg aaggacgggg gccccgggcg cggcggctgc gacaacccgg gcaagttcca     1080

ccacgtggag aagagcgcgt cgtgcgcgcc gctctgcacg cccggcgtgg acgtgtactg     1140

gagccgcgag gacaagcgct tcgcagtggt ctggctggcc atctgggcgg tgctgtgctt     1200

cttctccagc gccttcaccg tgctcacctt cctcatcgac ccggcccgct tccgctaccc     1260

cgagcgcccc atcatcttcc tctccatgtg ctactgcgtc tactccgtgg gctacctcat     1320

ccgcctcttc gccggcgccg agagcatcgc ctgcgaccgg gacagcggcc agctctatgt     1380

catccaggag ggactggaga gcaccggctg cacgctggtc ttcctggtcc tctactactt     1440

cggcatggcc agctcgctgt ggtgggtggt cctcacgctc acctggttcc tggccgccgg     1500

caagaagtgg ggccacgagg ccatcgaagc caacagcagc tacttccacc tggcagcctg     1560

ggccatcccg gcggtgaaga ccatcctgat cctggtcatg cgcagggtgg cgggggacga     1620

gctcaccggg gtctgctacg tgggcagcat ggacgtcaac gcgctcaccg gcttcgtgct     1680

cattcccctg gcctgctacc tggtcatcgg cacgtccttc atcctctcgg gcttcgtggc     1740

cctgttccac atccggaggg tgatgaagac gggcggcgag aacacggaca agctggagaa     1800

gctcatggtg cgtatcgggc tcttctctgt gctgtacacc gtgccggcca cctgtgtgat     1860

cgcctgctac ttttacgaac gcctcaacat ggattactgg aagatcctgg cggcgcagca     1920

caagtgcaaa atgaacaacc agactaaaac gctggactgc ctgatggccg cctccatccc     1980

cgccgtggag atcttcatgg tgaagatctt tatgctgctg gtggtgggga tcaccagcgg     2040

gatgtggatt tggacctcca agactctgca gtcctggcag caggtgtgca gccgtaggtt     2100

aaagaagaag agccggagaa aaccggccag cgtgatcacc agcggtggga tttacaaaaa     2160

agcccagcat ccccagaaaa ctcaccacgg gaaatatgag atccctgccc agtcgcccac     2220

ctgcgtgtga acagggctgg agggaagggc acaggggcgc ccggagctaa gatgtggtgc     2280

ttttcttggt tgtgtttttc tttcttcttc ttcttttttt ttttttataa aagcaaaaga     2340

gaaatacata aaaaagtgtt taccctgaaa ttcaggatgc tgtgatacac tgaaaggaaa     2400

aatgtactta aagggttttg ttttgttttg gttttccagc gaagggaagc tcctccagtg     2460

aagtagcctc ttgtgtaact aatttgtggt aaagtagttg attcagccct cagaagaaaa     2520

cttttgttta gagccctccc taaatataca tctgtgtatt tgagttggct ttgctaccca     2580

tttacaaata agaggacaga taactgcttt gcaaattcaa gagcctcccc tgggttaaca     2640

aatgagccat ccccagggcc cacccccagg aaggccacag tgctgggcgg catccctgca     2700

gaggaaagac aggacccggg gcccgcctca caccccagtg gatttggagt tgcttaaaat     2760

agactccggc cttcaccaat agtctctctg caagacagaa acctccatca aacctcacat     2820

ttgtgaactc aaacgatgtg caatacattt ttttctcttt ccttgaaaat aaaaagagaa     2880

acaagtattt tgctatatat aaagacaaca aaagaaatct cctaacaaaa gaactaagag     2940

gcccagccct cagaaaccct tcagtgctac attttgtggc tttttaatgg aaaccaagcc     3000

aatgttatag acgtttggac tgatttgtgg aaaggagggg ggaagaggga gaaggatcat     3060

tcaaaagtta cccaaagggc ttattgactc tttctattgt taaacaaatg atttccacaa     3120

acagatcagg aagcactagg ttggcagaga cactttgtct agtgtattct cttcacagtg     3180

ccaggaaaga gtggtttctg cgtgtgtata tttgtaatat atgatatttt tcatgctcca     3240

ctattttatt aaaaataaaa tatgttcttt agtttgctgc taaaaaaa                  3288


<210>  1430
<211>  3620
<212>  DNA
<213>  homo sapiens

<400>  1430
agcgccggcg aggcgcggga ggaggagaag cagtggggag gcgcagccgc tcacctgcgg       60

ggcagggcgc ggaggaggga cccgggctgc gcgctctcgg gccgaggaac caggacgcgc      120

ccggagcctc gcacgcggcc aagctcgggg cgtcccctcc cctcggccgg gcgaactcaa      180

ggggcgcagc tctttgcttt gacagagctg gccggcggag gcgtgcagag cggcgagccg      240

gcgagccagg ctgagaaact cgagccggga acaaagaggg gtcggactga gtgtgtgtgt      300

cggctcgagc tccgggcaga ggcatttggg cccgaggccc ccgctgtgac tccccgagac      360

tccgcagtgc cctccactgc ggagtccccg cgcttgccgg caaaaacttt attcttggca      420

aacttctctt tctcttcccc tcctcctcgg cccccatctt ctgctcctcc tccttctcta      480

gcagattaaa tgagcctcga gaagaaaaac cgaagcgaaa gggaagaaaa taagaagatc      540

taaaacggac atctccagcg tgggtggctc ctttttcttt ttcttttttt cccacccttc      600

aggaagtgga cgtttcgtta tcttctgatc cttgcacctt cttttggggc aaacggggcc      660

cttctgccca gatcccctct cttttctcgg aaaacaaact actaagtcgg catccggggt      720

aactacagtg gagagggttt ccgcggagac gcgccgccgg accctcctct gcactttggg      780

gaggcgtgct ccctccagaa ccggcgttct ccgcgcgcaa atcccggcga cgcggggtcg      840

cggggtggcc gccggggcag cctcgtctag cgcgcgccgc gcagacgccc ccggagtcgc      900

cagctaccgc agccctcgcc gcccagtgcc cttcggcctc gggggcgggc gcctgcgtcg      960

gtctccgcga agcgggaaag cgcggcggcc gccgggattc gggcgccgcg gcagctgctc     1020

cggctgccgg ccggcggccc cgcgctcgcc cgccccgctt ccgcccgctg tcctgctgca     1080

cgaacccttc caactctcct ttcctccccc acccttgagt tacccctctg tctttcctgc     1140

tgttgcgcgg gtgctcccac agcggagcgg agattacaga gccgccggga tgccccaact     1200

ctccggagga ggtggcggcg gcggggggga cccggaactc tgcgccacgg acgagatgat     1260

ccccttcaag gacgagggcg atcctcagaa ggaaaagatc ttcgccgaga tcagtcatcc     1320

cgaagaggaa ggcgatttag ctgacatcaa gtcttccttg gtgaacgagt ctgaaatcat     1380

cccggccagc aacggacacg aggtggccag acaagcacaa acctctcagg agccctacca     1440

cgacaaggcc agagaacacc ccgatgacgg aaagcatcca gatggaggcc tctacaacaa     1500

gggaccctcc tactcgagtt attccgggta cataatgatg ccaaatatga ataacgaccc     1560

atacatgtca aatggatctc tttctccacc catcccgaga acatcaaata aagtgcccgt     1620

ggtgcagcca tcccatgcgg tccatcctct cacccccctc atcacttaca gtgacgagca     1680

cttttctcca ggatcacacc cgtcacacat cccatcagat gtcaactcca aacaaggcat     1740

gtccagacat cctccagctc ctgatatccc tactttttat cccttgtctc cgggtggtgt     1800

tggacagatc accccacctc ttggctggca aggtcagcct gtatatccca tcacgggtgg     1860

attcaggcaa ccctacccat cctcactgtc agtcgacact tccatgtcca ggttttccca     1920

tcatatgatt cccggtcctc ctggtcccca cacaactggc atccctcatc cagctattgt     1980

aacacctcag gtcaaacagg aacatcccca cactgacagt gacctaatgc acgtgaagcc     2040

tcagcatgaa cagagaaagg agcaggagcc aaaaagacct cacattaaga agcctctgaa     2100

tgcttttatg ttatacatga aagaaatgag agcgaatgtc gttgctgagt gtactctaaa     2160

agaaagtgca gctatcaacc agattcttgg cagaaggtgg catgccctct cccgtgaaga     2220

gcaggctaaa tattatgaat tagcacggaa agaaagacag ctacatatgc agctttatcc     2280

aggctggtct gcaagagaca attatggtaa gaaaaagaag aggaagagag agaaactaca     2340

ggaatctgca tcaggtacag gtccaagaat gacagctgcc tacatctgaa acatggtgga     2400

aaacgaagct cattcccaac gtgcaaagcc aaggcagcga ccccaggacc tcttctggag     2460

atggaagctt gttgaaaacc cagactgtct ccacggcctg cccagtcgac cccaaaggaa     2520

cactgacatc aattttaccc tgaggtcact gctagagacg ctgatccata aagacaatca     2580

ctgccaaccc ctctttcgtc tactgcaaga gccaagttcc aaaataaagc ataaaaaggt     2640

tttttaaaag gaaatgtaaa agcacatgag aatgctagca ggctgtgggg cagctgagca     2700

gcttttctcc cctcatatct gcgtgcactt cccagagcat cttgcatcca aacctgtaac     2760

ctttcggcaa ggacggtaac ttggctgcat ttgcctgtca tgcgcaactg gagccagcaa     2820

ccagcacatc catcagcacc ccagtggagg agttcatgga agagttccct ctttgtttct     2880

gcttcatttt tctttctttt cttttctcct aaagctttta tttaacagtg caaaaggatc     2940

gttttttttt gcttttttaa acttgaattt ttttaattta cactttttag ttttaatttt     3000

cttgtatatt ttgctagcta tgagctttta aataaaattg aaagttctgg aaaagtttga     3060

aataatgaca taaaaagaag ccttcttttt ctgagacagc ttgtctggta agtggcttct     3120

ctgtgaattg cctgtaacac atagtggctt ctccgccctt gtaaggtgtt cagtagagct     3180

aaataaatgt aatagccaaa cccactctgt tggtagcaat tggcagccct atttcagttt     3240

attttttctt ctgttttctt cttttctttt tttaaacagt aaaccttaac agatgcgttc     3300

agcagactgg tttgcagtga attttcattt ctttccttat cacccccttg ttgtaaaaag     3360

cccagcactt gaattgttat tactttaaat gttctgtatt tgtatctgtt tttattagcc     3420

aattagtggg attttatgcc agttgttaaa atgagcattg atgtacccat tttttaaaaa     3480

agcaaggcac agcctttgcc caaaactgtc atcctaacgt ttgtcattcc agtttgagtt     3540

aatgtgctga gcattttttt aaaagaagct ttgtaataaa acatttttaa aaattgtcat     3600

ttaaaaaaaa aaaaaaaaaa                                                 3620


<210>  1431
<211>  4451
<212>  DNA
<213>  homo sapiens

<400>  1431
acgcgccgcg tgcccggccg cgcccagcag ggtttccagg cctgaggtgc ccgccctggc       60

cccaggagaa tgaaccagcc gcagaggatg gcgcctgtgg gcacagacaa ggagctcagt      120

gacctcctgg acttcagcat gatgttcccg ctgcctgtca ccaacgggaa gggccggccc      180

gcctccctgg ccggggcgca gttcggaggt tcaggtcttg aggaccggcc cagctcaggc      240

tcctggggca gcggcgacca gagcagctcc tcctttgacc ccagccggac cttcagcgag      300

ggcacccact tcactgagtc gcacagcagc ctctcttcat ccacattcct gggaccggga      360

ctcggaggca agagcggtga gcggggcgcc tatgcctcct tcgggagaga cgcaggcgtg      420

ggcggcctga ctcaggctgg cttcctgtca ggcgagctgg ccctcaacag ccccgggccc      480

ctgtcccctt cgggcatgaa ggggacctcc cagtactacc cctcctactc cggcagctcc      540

cggcggagag cggcagacgg cagcctagac acgcagccca agaaggtccg gaaggtcccg      600

ccgggtcttc catcctcggt gtacccaccc agctcaggtg aggactacgg cagggatgcc      660

accgcctacc cgtccgccaa gacccccagc agcacctatc ccgccccctt ctacgtggca      720

gatggcagcc tgcacccctc agccgagctc tggagtcccc cgggccaggc gggcttcggg      780

cccatgctgg gtgggggctc atccccgctg cccctcccgc ccggtagcgg cccggtgggc      840

agcagtggaa gcagcagcac gtttggtggc ctgcaccagc acgagcgtat gggctaccag      900

ctgcatggag cagaggtgaa cggtgggctc ccatctgcat cctccttctc ctcagccccc      960

ggagccacgt acggcggcgt ctccagccac acgccgcctg tcagcggggc cgacagcctc     1020

ctgggctccc gagggaccac agctggcagc tccggggatg ccctcggcaa agcactggcc     1080

tcgatctact ccccggatca ctcaagcaat aacttctcgt ccagcccttc tacccccgtg     1140

ggctcccccc agggcctggc aggaacgtca cagtggcctc gagcaggagc ccccggtgcc     1200

ttatcgccca gctacgacgg gggtctccac ggcctgcaga gtaagataga agaccacctg     1260

gacgaggcca tccacgtgct ccgcagccac gccgtgggca cagccggcga catgcacacg     1320

ctgctgcctg gccacggggc gctggcctca ggtttcaccg gccccatgtc actgggcggg     1380

cggcacgcag gcctggttgg aggcagccac cccgaggacg gcctcgcagg cagcaccagc     1440

ctcatgcaca accacgcggc cctccccagc cagccaggca ccctccctga cctgtctcgg     1500

cctcccgact cctacagtgg gctagggcga gcaggtgcca cggcggccgc cagcgagatc     1560

aagcgggagg agaaggagga cgaggagaac acgtcagcgg ctgaccactc ggaggaggag     1620

aagaaggagc tgaaggcccc ccgggcccgg accagcccag acgaggacga ggacgacctt     1680

ctccccccag agcagaaggc cgagcgggag aaggagcgcc gggtggccaa taacgcccgg     1740

gagcggctgc gggtccgtga catcaacgag gcctttaagg agctggggcg catgtgccaa     1800

ctgcacctca acagcgagaa gccccagacc aaactgctca tcctgcacca ggctgtctcg     1860

gtcatcctga acttggagca gcaagtgcga gagcggaacc tgaatcccaa agcagcctgt     1920

ttgaaacggc gagaagagga aaaggtgtca ggtgtggttg gagaccccca gatggtgctt     1980

tcagctcccc acccaggcct gagcgaagcc cacaaccccg ccgggcacat gtgaaaggta     2040

tgcctccgtg ggacgagcca cccgctttca gccctgtgct ctggccccag aacggccact     2100

cgagaccccg ggcttcatcc acatccacac ctcacacacc tgttgtcagc atcgagccaa     2160

caccaacctg acaaggttcg gagtgatggg ggcggccaag gtgacactgg gtccaggagc     2220

tccctggggc cctggcctac cactcactgg cctcgctccc cctgtccccg aatctcagcc     2280

accgtgtcac tctgtgacct gtcccatgga tcctgaaact gcatcttggc cctgttgcct     2340

gggctgacag gagcattttt tttttttcca gtaaacaaaa cctgaaagca agcaacaaaa     2400

catacacttt gtcagagaag aaaaaaatgc cttaactata aaaagcggag aaatggaaac     2460

atatcactca agggggatgc tgtggaaacc tggcttattc ttctaaagcc accagcaaat     2520

tgtgcctaag cgaaatattt tttttaagga aaataaaaac attagttaca agattttttt     2580

tttcttaatg tagatgaaaa ttagcaagga tgctgccttt ggtctctggt ttttttaagc     2640

tttttttgca tatgttttgt aagcaacaaa tttttttgta taaaagtccc gtgtctctcg     2700

ctatttctgc tgctgttcct agactgagca ttgcatttct tgatcaacca gatgattaaa     2760

cgttgtatta aaaagacccc gtgtaaacct gagccccccc gtcccccccc ccccccggaa     2820

gccactgcac acagacagaa cggggacagg cggcgggtct tttgtttttt tgatgttggg     2880

ggttctcttg gttttgtcat gtggaaagtg atgcgtgggc gttccctgat gaaggcacct     2940

tggggcttcc ctgccgcatc ctctcccctc aggaagggga ctgacctggg cttgggggaa     3000

gggacgtcag caaggtggct ctgaccctcc caggtgactc tgccaagcag ctgtggcccc     3060

cagggctacc ctacacaacg ccctccccag gcccccctaa gctgctctcc cttggaacct     3120

gcacagctct ctgaaatggg gcattttgtt gggaccagtg acccctggca tggggaccac     3180

accctggagc ccggtgctgg ggacctcctg gacaccctgt ccttcactcc tttgccccag     3240

ggacccaggc tcatgctctg aactctggct gagaggatgc tgctcaggag ccagcacagg     3300

acacccccca ccccacccca ccatgtcccc attacaccag agggccatcg tgacgtagac     3360

aggatgccag gggcctggcc agcctccccc aatgctgggg agcatccctg ggcctggggc     3420

cacacctgct gccctccctc tgtgtggtcc aagggcaaga gtggctggag ccgggggact     3480

gtgctggtct gagccccacg aaggccttgg gctgtgcgtc cgaccctgct gcagaaccag     3540

cagggtgtcc cctcgggccc atctgtgtcc catgtcccag cacccaggcc tctctccagg     3600

tctccttttc tggtcttttg ccatgagggt aaccagctct tcccagctgg ctggggactg     3660

tcttgggttt aaaactgcaa gtctcctacc ctgggatccc atccagttcc acacgaacta     3720

gggcagtggt cactgtggca cccaggtgtg ggcctggcta gctgggggcc ttcatgtgcc     3780

cttcatgccc ctccctgcat tgaggccttg tggacccctg ggctggctgt gttcatcccc     3840

gctgcaggtc gggcgtctcc ccccgtgcca ctcctgagac tcccaccgtt acccccagga     3900

gatcctggac tgcctgactc ccctccccag actggcttgg gagcctgggc cccatggtag     3960

atgcaaggga aacctcaagg ccagctcaat gcctggtatc tgcccccagt ccaggccagg     4020

cggaggggag gggctgtccg gctgcctctc ccttctcggt ggcttcccct acgccctggg     4080

agtttgatct cttaagggaa cttgcctctc cctcttgttt tgctcctggc cctgccccta     4140

ggtctgggtg ggcagtggcc ccatagcctc tggaactgtg cgttctgcat agaattcaaa     4200

cgagattcac ccagcgcgag gaggaagaaa cagcagttcc tgggaaccac aattatgggg     4260

ggtggggggt gtgatctgag tgcctcaaga tggttttcaa aaaaattttt ttaaagaaaa     4320

taattgtata cgtgtcaaca cagctggctg gatgattggg actttaaaac gaccctcttt     4380

caggtggatt cagagacctg tcctgtatat aacagcactg tagcaataaa cgtgacattt     4440

tataacgatg c                                                          4451


<210>  1432
<211>  1350
<212>  DNA
<213>  homo sapiens

<400>  1432
ggggacgctc tcagctctca gtgcctggcc cagcttcctt caaaatgtat actatttacg       60

aaatcctgtg caagctcagc ttggagggtc atcactctac accctcaggt gcatatgggt      120

cagtcaaagc ctacaccaac tttgatgctg agggggatgc tttgaacatt gaaaggacca      180

tcaggacaaa aggtgtgggt aagttcacca ttgtcaacat tttgaccaac agcaggaatg      240

ctcggagaga ggatgttgcc tttgcctagc agagaaggac cacaaaggaa cttacatcag      300

cactgaagtc agccttactg gccacctgga gacagtcatt ttgggcctat tgaagacacc      360

tgctcagtat gatgcttctg agctaaaagc ttccatgaag gggctgggaa ctgaggagga      420

ctccctcgtt gagatcatct gctcaacaac caaccaggag ctccaggaaa ttaacagagt      480

ctacaaagaa atgtacaaaa ctgatctgga gaaggacatt atttcggaca catatggtga      540

cttctgcaag ctgatgtttg ccctggcaaa tgttagaaga ccagaggatg gctctgtcgt      600

tgattatgaa ctgattgacc aagatgcccg ggatttctgt gatgctggag tgaagaggaa      660

aagaactgat gttcccaagt ggatcagcat gatgaccgag tagagcatgt cccacctcca      720

gaaagtattt gataggtaca agagctacag cccatcaaga gagagcatca agaaagaggt      780

taaaggagac ctggaaaatg ctttcctgaa cctggtccag tgcattcaga acaagcccct      840

gtattttgct gattggctgt actactccat gaagggccgg gggctcgaga taaggtcctg      900

atcagaatca tcgtctcccg cagtgaagtg gacatgttga aaattaggtc tgaattcaag      960

agaaagtatg gcatgtcccc gtactattac atccagcaag acactaagaa cgactaccca     1020

aaaagcactg ctgtacctgt gtggtggaga tgactgaagc ccaacatagc ttgagcttcc     1080

agaaacggtg ctccccacgc ttccagctaa caggtctaga aaaccagctt gtggctaaca     1140

gtccctgtgg ccgtccctgt gaagatgaca ttagcattgc ccccaacctc attttagttg     1200

cgtaagcata gcctggcttt cctgtctagt ctctcctgta agccaaagaa atgtacattc     1260

caagcagttg gaagtgaaat ctatgatgtg aaacactttg cctcctgtgt actgtgtcat     1320

aaacagatga ataaactgaa tttgtacttt                                      1350


<210>  1433
<211>  1343
<212>  DNA
<213>  homo sapiens

<400>  1433
catctgggga cgctctcagg tcttggtgcc cagcccagct tccttcaaaa tatctgctgt       60

tcatgaaatc ctgtgcaagc tcagcttgga gggtgaacac tctacactcc caagtgcatt      120

tgggtcagtc aaagcctaca ccaaatttga tgctgagcag gatgctttga acattgaaat      180

ggccatcaag accaaaggtg tggatgagat caccactgtc aacattttga ctaaccacag      240

caatgcacag agacaggata ttgccttcac ctaccagaga aggaccaaaa aggaacttgt      300

atcagcactt aagtcagcct tatctggcca cctagatagt ggctttgggc ctattaaaga      360

cacctgctca gtatgatgct tctgagctaa aatcttccat gaaggggctg ggaaccaaca      420

aggactccct cattgagatc atctgctcaa gaaccaacca agagctgcag gaaattaaca      480

gagtctacaa ggaaatgtac aagactgatc tggagaagga cattatttcg gacacatctg      540

gtgacttctg caagctgatg gttgccctgg caaagggtag aagagcagag gatggctctg      600

tcattgatta tgaactgatt gaccaagatg cccgggatct ctatgacgct ggggtgaaga      660

ggaaaggaac tgaagttccc aagtggatca gcgtcatgac cgagcggagc atgtcccact      720

tccagaaagt atttgatagg tacaagagct acagtcctta tgacatgttg gagagcatca      780

agaaagaggt taaaggagac ctggaaaatt ctttcctgaa cctggtccag tgtattcaga      840

acaagcccct gtatttcgct gaccggctgt acgactccat aatgggcatg gggactcaag      900

ataaggtcct gatcagaatc atggtctccc acaatgaagt ggacatgttg aaaattaggt      960

ctgaattcaa gagaaagtat agcaagtccc tgtactatta catccagcaa gacactaagg     1020

gtgctgtacc tgtgtggtgg agatggctga agtccgacac agcacgagcg tccagaaatg     1080

gtgctcccca tgcttccagc taacaggtct agaaaacccg cttgtgacta gcagtccctg     1140

tggctgttcc tgtgaggatg acgttagcat tgcccccaac ctcattttag ttgcctaagc     1200

attgcctggc tttcctgtct agtctctcct gtaagccaaa gaaatgaaca ttccaaggaa     1260

ttggaagtga agtctatgat gtgaaacact ttgcctcctg tgtactgtgt cataaacgga     1320

ttaataaact gaatttgtac ttt                                             1343


<210>  1434
<211>  1595
<212>  DNA
<213>  homo sapiens

<400>  1434
gcaggaccgt cattgacgcc atgagcgcgc tgctgcggct gctgcgcacg ggtgccccag       60

ccgctgcgtg cctgcggttg gggaccagtg cagggaccgg gtcgcgccgt gctatggccc      120

tgtaccacac tgaggagcgc ggccagccct gctcgcagaa ttaccgcctc ttctttaaga      180

atgtaactgg tcactacatt tccccctttc atgatattcc tctgaaggtg aactctaaag      240

aggaaaatgg cattcctatg aagaaagcac gaaatgatga atatgagaat ctgtttaata      300

tgattgtaga aatacctcgg tggacaaatg ctaaaatgga gattgccacc aaggagccaa      360

tgaatcccat taaacaatat gtaaaggatg gaaagctacg ctatgtggcg aatatcttcc      420

cttacaaggg ttatatatgg aattatggta ccctccctca gattctttct tgtggagaag      480

ttattcatgt gaagatcctt ggaattttgg ctcttattga tgaaggtgaa acagattgga      540

aattaattgc tatcaatgcg aatgatcctg aagcctcaaa gtttcatgat attgatgatg      600

ttaagaagtt caaaccgggt tacctggaag ctactcttaa ttggtttaga ttatataagg      660

taccagatgg aaaaccagaa aaccagtttg cttttaatgg agaattcaaa aacaaggctt      720

ttgctcttga agttattaaa tccactcatc aatgttggaa agcattgctt atgaagaagt      780

gtaatggagg agctataaat tgcacaaacg tgcagatatc tgatagccct ttccgttgca      840

ctcaagagga agcaagatca ttagttgaat cggtatcatc ttcaccaaat aaagaaagta      900

atgaagaaga gcaagtgtgg cacttccttg gcaagtgatt gaaacatctg aaattctgct      960

gtcaagattc ccatctctaa ggactccaag tgctagagac aagggggtct atgagcattt     1020

actgacttcc tgttaaaact tcattttttc aaactttttg agctatgcaa tatataaata     1080

aacagtaaga attttaaatt actctccttt ggacatttat tgatataaaa agaagatttt     1140

ggccaggcac ggtggctcat gcctgtaatt tcagcacttt gggaggccga ggtgggcaga     1200

tcacaaggtc aggagttcaa gaccagcctg gccagtatgt tgaaacccca tctctattaa     1260

aaatacaaaa attagccagg cgtggtggtg catgcctgta gacccagcta ctcaggaggc     1320

tgaggcagaa gaactgcttg agcccaggag gcagaggttg cagtgagcag agattgtgcc     1380

actgcactcc agcctaggcg acagagagag actccgtctc aaaaaaaaaa aaaagatttt     1440

gtttcatttc atagcacaaa tttagaggca ttgagttgac catttctagt ttctatacct     1500

gaaggaaccc attgatttta ccagttttta tttctgtaga ttggatgtaa aaatcacaga     1560

ttcaataaat taataaactt tgtgtaaaaa aaaaa                                1595


<210>  1435
<211>  6144
<212>  DNA
<213>  homo sapiens

<400>  1435
gtctggtgag gaaatcatca ccctaggacg taaaccctcc cgcccttctt tcagctctta       60

aaaaaagcct gccacgaaag tccctactgc gttgctgcga acgtagcttt gagaagctgg      120

cgcccagtga tggggcaaac agccatgccc ttccagcagc cgtgaaagcc ccaacagcaa      180

actgcctggg agcggggcag gtcaccaact tcgttgctcg aactccctgg gtgcccgccg      240

cggtggttac aaagggggtc aagagtgccg gacccagccg cgcggagccc accattgcgg      300

cccgaggggg acccgacggg ggcccgacgg tgtggcgtgg cgcaaggagc gcgcctgcct      360

tctctcgccg ccgggaacgg gctgcaccaa tggccagatt ccagcaagat tatggaagag      420

catagctaca tacaaaagga gctagattta caaaatggta gcttagagga agactctgtg      480

gtgcattctg ttgagaacga ttcccaaaac atgatggaga gcctcagccc aaagaaatac      540

tcttccagtc tgagatttaa agccaatgga gactattctg gctcctattt aaccctctca      600

caacctgtgc ctgcaaagag aagcccttct cctttgggaa ccagtgtcag aagcagcccc      660

tccttagcca aaatccaggg aagcaagcag ttctcttatg atggaactga caaaaatatt      720

cctatgaaac ctccaactcc tttactcaac actacatcct ccctcagtgg atatccactt      780

ggaagagcag actttgatca ttatactggc cgggacagtg aaagggcctt gaggctctca      840

gagaagcctc cctattccaa atatagctca aggcataaat cgcatgacaa tgtctactct      900

cttggagggc tggaaggtcg gaaggcatct ggctcgctcc tggccatgtg gaatggaagt      960

tccctgagtg atgctggccc gcctcctatc agcagatcgg gagccgcaag catgccttca     1020

agcccaaagc aagccaggaa aatgagcatt caggacagcc tggcgcttca acccaagtta     1080

actagacaca aggagcttgc atctgaaaac atcaatttga gaactaggaa gtactccagc     1140

agcagcctga gtcacatggg agcctacagc cgatcacttc ccaggttgta cagagccaca     1200

gagaaccagc tgacacctct cagcttgcct ccaagaaact ctctgggcaa ttccaaacga     1260

acaaaacttg gggaaaagga tctacctcat agcgtaatag acaatgacaa ttaccttaat     1320

ttttcttctt tgagctcagg ggctttaccc tataaaacct ctgcttctga aggcaatcct     1380

tatgtaagtt ctaccctcag tgtccctgcc agtccacgag tggctcggaa gatgcttctg     1440

gcctccacct cctcctgtgc ctctgatgac tttgatcagg cttcatatgt ggggacaaac     1500

ccgagtcatt cacttcttgc tggagagtca gacagagttt ttgcgaccag gaggaacttc     1560

tcttgtggat ctgtggaatt tgatgaggca gatttggaaa gcctcagaca ggcctcagga     1620

accccccagc ctgcccttcg ggaacggaaa agcagtatta gctccatttc aggacgtgat     1680

gacctgatgg attatcaccg gcggcagagg gaggaaagac tcagggagca ggaaatggag     1740

cgattggaga gacagcgtct ggagaccatc ctcagtctct gtgctgaata cacaaagcct     1800

gacagtcgct tatctactgg gaccaccgtg gaagatgtgc agaaaatcaa caaggagctt     1860

gagaagctgc agctctctga tgaggagtct gtgtttgagg aagccctcat gagccctgac     1920

acaagataca ggtgccaccg gaaagactcc ctccctgatg cagacttggc aagctgtggg     1980

agtctcagtc agagcagtgc cagcttcttt acccccagga gcaccaggaa tgatgaacta     2040

ctcagtgacc tcacccggac tcctccacca ccatcctcca cctttccgaa agcttccagc     2100

gagtcctctt atctaagtat cctaccaaag accccagagg gtataagtga agaacagaga     2160

tctcaggagt tggctgcaat ggaagaaacc cggatagtca ttctgaacaa cctcgaggaa     2220

cttaagcaaa aaatcaaaga cataaatgat cagatggatg agtctttcag agagttggat     2280

atggaatgtg ctcttttgga tggagaacag aaatctgaaa caactgaact tatgaaggag     2340

aaggagattt tggatcatct aaaccggaaa atagctgaac tggaaaagaa cattgttggt     2400

gaaaagacca aggagaaggt aaagcttgat gctgaaaggg aaaaactaga gaggcttcag     2460

gagctttact ccgagcagaa gacccagctg gacaattgtc ctgagtccat gagggaacag     2520

ttacaacaac aactgaagag ggatgctgac ctgttggatg ttgaaagcaa acactttgaa     2580

gacctggagt tccagcagct tgaacatgag agccgtctag atgaagaaaa ggagaacttg     2640

actcaacagc tcctgcgtga agttgctgaa tatcaacgga acatcgtttc tagaaaggaa     2700

aaaatttctg cattgaaaaa gcaagccaat cacattgttc agcaggctca gagagagcaa     2760

gatcattttg tgaaagaaaa gaataattta ataatgatgt tgcaaagaga aaaggagaat     2820

ctttgtaatt tggaaaagaa atactccagc ctctctgggg ggaaagggtt tcccgttaac     2880

cccaatactt taaaagaggg ctatatcagt gtaaatgaga ttaatgagcc gtgtggcaat     2940

tccacgaatc tatccccttc cactcagttt cctgctgatg ctgatgctgt tgccactgag     3000

cctgccacag ctgtgctggc gagccagcca cagagtaaag agcactttag aagtctggaa     3060

gaaaggaaaa aacagcataa agaaggcctc tatctgagtg atactttgcc tcgaaagaaa     3120

accacatctt ccatctcccc acatttcagc agtgctacta tggggagaag catcacccca     3180

aaggcccatc tgcccctagg acagagtaac agctgtggaa gtgtgctccc tccctcactg     3240

gcagccatgg ccaaagactc agaatctcgg aggatgctca gaggttataa tcaccaacag     3300

atgagtgaag gacacaggca gaaatctgaa ttttataacc gcacagcatc tgaatcaaat     3360

gtctacttga atagtttcca ttatccagat cacagctaca aggaccaggc ctttgatact     3420

ctgagcctcg atagctctga tagcatggag accagcatct ctgcttgctc accagacaac     3480

atctctagtg ccagcacttc aaatattgct agaatagaag aaatggagag acttttgaag     3540

caggctcatg cagaaaagac gcggctgctc gaatccaggg aacgggaaat ggaagccaaa     3600

aaacgagccc tggaagaaga aaaacgacgc cgggaaatcc tggaaaaacg attacaggaa     3660

gaaactagcc agaggcagaa gttaatagaa aaggaagtaa aaataaggga gagacaaagg     3720

gcacaggctc gtcctttgac acgctacctg cctgtccgga aggaagactt tgatttgcgg     3780

agccatgtag agactgctgg ccacaatatt gacacctgtt accatgtatc aatcacagag     3840

aagacctgcc gaggattcct catcaaaatg ggtgggaaaa ttaaaacgtg gaaaaaacgt     3900

tggtttgttt ttgatcggaa caagcgaaca ttctcttatt atgcagacaa gcatgaaact     3960

aaattgaaag gagtaatata ctttcaagcc attgaagaag tctattatga tcacctcaag     4020

aatgctaata agagtcctaa tccgttactc acctttagcg tcaagactca tgacagaatc     4080

tattatatgg tagccccatc gccagaagcc atgcggatct ggatggatgt tatagttacg     4140

ggggcagaag gttacactca cttcttgttg tagtgaactg aggcaacagt ccacttcagg     4200

gcagacggca ataatctctt acaagaatga agccatattc aaccccagat gagaaaaccc     4260

aacagatcca tcccttgagc tgtaaacact cagaactcct ttcatatcaa gacaagttat     4320

ttgtaaaaaa taaagaaggg gttttaatac aaaccttcat aataaatagc aaaataattg     4380

aagcttccat gagaaagaaa acactatttt gataaattgg atcacttata ggaacatttc     4440

taataaactg tttttaatca gttgtcggat ttggtgaaat aaactaaaca ggttacagaa     4500

tatctgtatg tacttggaaa tacagaataa ctttatcacc caaatcactg gcattgacat     4560

tattggtaat caactggctt tttttaaaaa aggtagcatt ttgttgacag ttattttgta     4620

aacataagca aataagggct tggagggaaa tacattttag gaggagtttt gccttaattt     4680

tttaagtact gcaccaaaac caaagagctg acctgacttc tgtggaacag tagtaactgc     4740

aagtgatgaa ctgcatttcg tattgttctg tatatttcaa aatggtattt tgatgccatc     4800

aaatgcccag gaaattgact ttgcagtgtc accactggtg taagctacta tatatgtata     4860

tatatatgta gtaaaccact ttttgtaaaa gaagaaagag caaaaagctg tgtgttttag     4920

aaaaaaaagc caggttacgc aacaggcatt ctgtcatgtt gaacaatttt aaataaagag     4980

aatatctggt gttaggagct tgttttgctg aagatttctc cattcctggt gctgagaata     5040

aaggcaacca gtagccaatg tcctttagat tgtctgattt ctttttgttg tggagcacac     5100

ctgctaactg ctccctcaac ataactatga aatcatagct ctgttttcac caaagaacag     5160

accaattaac atacttattt gcagaagtgg tgtagttcta taaaacggca aatgaagttc     5220

aacttaatat tctctataat gtattatttt attttatttt ttacaattag cctttttttt     5280

agttaatttt tgtcaaatga aacgacttca ggcaagtctc ttttataatg gtttttcaag     5340

tgccatttat tctagtttat catgttttgc atgtttgaaa gtatgaatgt gctctttcct     5400

aaaacatggc aaatgaatag atgtagagaa taacaatatt acttacaaga tgaaatgatt     5460

agattagaag tgtcccttta ttaaactttg tcagcctgac tgggtacaat tcttttgtta     5520

atttgcagtg tggtttgtat acacgtatac gtgttatcaa taataagatt ttgcaactgg     5580

atgacacaag attttacttg aacagtgaag gacaaaaatc atgattgtgg aagatatttt     5640

taaaatctga ttttgcagcg atcactttta aaccctgtag tgatgtaaga ctaaaatata     5700

attgctaaga ttttgttggt taatgtaaag atatgacttt tctgcactgt actctcttca     5760

taggattgta aaggtgttct aatccaattg catgatgtag taagcctctt aaatatgtgt     5820

gttaaatata ttgagtttgg attaaaatgt tgacatgatt tcacatttga aaataaactc     5880

atctcttatt ttgaagttac ctatctgtag tatgatggag gatgaattaa tcgcaaatga     5940

cagttgtaga aactatgtaa agtttgttgt gtgctaacat tatgatttgt agtgtataaa     6000

ctgaagtatt ccaatagaag tatctctggt tacatcctat tgcttacaaa atgaaatgaa     6060

ccctgaaaaa ctctgacatc atattgttgt ctgtttacac agatacattt attgctgggg     6120

attgcaaaaa aaaaaaaaaa aaaa                                            6144


<210>  1436
<211>  11347
<212>  DNA
<213>  homo sapiens

<400>  1436
gcggggagcc ggcggttatc tgggcggcgg agcgctcaca atgtggcagg agacagaaaa       60

gataagatgc tcccaagtcc cttgcagctc tcttcagaag aaaaatcact agtgctctgc      120

tcttgccata ataccaaacc tttttgactc atgctttggt gctgcaacac tggaagaatt      180

gcacacagtt tccaggaata tctttttttc atttgagtga ttctttgtgg atgagaaaag      240

atttgagtct taataattac cttgttttaa agctatttct ttatagtctg aactgtttaa      300

taaattgggc cacttaccaa tgagccacac agccagttct tgtcaggagc tggttgaaaa      360

ctgtgctgtg catgtagcag gaatggcaca agaagatagc cgtcgtggtc aagtgccatc      420

ttccttttat catggtgcca accaagaact tgacctgtcc accaaagtgt acaaaaggga      480

atcaggaagt ccttattctg tgttagtgga caccaagatg agcaaaccgc atctccatga      540

aacagaagaa cagccatatt tcagggagac aagagcagtg tctgacgtgc atgctgttaa      600

ggaagaccgg gagaattctg atgacacaga ggaggaagag gaagaagtct cttacaaaag      660

ggagcagatc atagtggagg taaaccttaa taatcaaaca ttaaatgtat ctaaagggga      720

aaagggtgtc tcttctcagt ccaaagagac tcctgttctt aagacaagca gtgaggagga      780

agaggaagag agtgaggaag aggccacaga tgacagcaat gactatggag agaatgaaaa      840

gcagaagaaa aaggagaaga tagtagagaa agtcagcgtt acacaaagga gaaccaggag      900

agctgcctct gttgccgcag ctaccacttc ccctactccc agaactacaa gaggtcgtag      960

gaagagtgta gagccaccta agcgtaagaa gcgggccaca aaggagccca aagcaccagt     1020

ccagaaagct aagtgtgaag agaaagagac tctgacctgt gagaagtgcc ccagggtatt     1080

taacactcgc tggtacctgg agaagcacat gaacgttact cataggcgca tgcagatttg     1140

tgataaatgt ggcaagaagt ttgtcctgga aagtgagctg tcccttcacc agcaaacaga     1200

ctgtgaaaaa aacattcagt gtgtttcctg taacaaatcg ttcaagaaac tctggtccct     1260

tcatgaacat atcaagatcg tccatggata tgcagaaaag aaattttcct gtgaaatttg     1320

tgagaagaaa ttctatacca tggctcatgt gcggaaacac atggttgcac acacaaaaga     1380

catgccattt acatgcgaaa cctgtggaaa atcattcaaa cgcagtatgt cactcaaggt     1440

gcactccttg cagcattctg gagagaagcc ctttagatgc gagaactgtg acgaaaggtt     1500

tcagtacaag taccagctac gctcccacat gagcattcat attgggcaca aacagttcat     1560

gtgccagtgg tgtggcaagg atttcaacat gaagcagtac ttcgacgaac acatgaaaac     1620

acacactgga gagaaaccct ttatctgtga aatctgtggc aaaagcttca ccagccgccc     1680

caacatgaag agacaccgca gaactcacac aggcgagaag ccctatccat gtgatgtgtg     1740

tggccagcgg ttccgcttct cgaacatgct taaggcccac aaggagaagt gctttcgggt     1800

gaccagcccc gtgaatgtgc cacctgctgt ccagatccca cttacaactt ccccagccac     1860

cccagttcct tctgtggtga acacagccac aaccccaacc cctccaatca atatgaatcc     1920

tgtaagcact cttccccctc ggcccatccc ccaccccttc tcacacctgc acatccaccc     1980

acaccctcac cacccacacc accttcccat ccctccagtc cctcacctcc cgccacctcc     2040

agctctcttt aagagtgagc ctttaaatca tagaggccag agtgaggaca actttctgcg     2100

gcacctggca gagaagaaca gttcagcaca gcatcattaa catccgtctc cttagtgtgt     2160

tctccaggag acacgtcccc atgtgtgagc gtgcacagag ggagtcggtg agcatttcct     2220

tagttctcag actctcctcc gcctctacca agagcttcgc cagtgtcact gaatcaacag     2280

atccaaggga atgaacaaga agactacctt gagctcacag agggactgtc atctaaacca     2340

ggggaaccac tgaactaaag cccaatttgc ttgcattttc tgatgacttt tataagtttc     2400

aaatactcag acttgtggaa ttttataatt tcatatcagc tgatgaggta tgcttgcttt     2460

tatatcccag acttctcctc aaagagggga taggcctggt ttcctttgta ctaatcggga     2520

aggctgtgag attaatccag agcattaatt gtatcactgt gtatggtaag gaattctttt     2580

cagcttttgg tgccagctac agagttgagc tggccatgtt tcacagtata tcaagcatta     2640

tagagaaaga cagaaatttt cttctttgtg tagctctcct aacgcactct ttattttact     2700

acagaaatta ttttagagtt tttgtataga cttctttggt agtctgtttc taaaatgaaa     2760

tgtatttcaa taagcagtgt aattttttca gtgtagctga acctatgttg taaaatagaa     2820

aaaaattttt ataatcatca aaatgtgatt cttaaagatg catataactt ctataattca     2880

aagctattct tacatccgta caactcaaaa ggtgcttcag agactagatg tatctgagag     2940

ggtctccaga ccaggttact gcaaaaatga ggttttgctt tcaggatttg gcgtaaatac     3000

ttggtagttt tgacatctct gcttaacact caagagaggc tccctaatgt gctcctgtcc     3060

tccatgttct gcttggcttc gttagtgcat tacatgaaat gatttgcagg ggatggggcc     3120

ttttccaggg aagtcaccta aagcttgcat gttttgaaaa tttgaataag gctgtttgct     3180

gacaggagga ggaagtagtg gagatcattt catctcagtc acgtctgttt ctcacttccc     3240

ttaggaattg tgttgatgtt taacttttat gggatgacaa attgaaatcg ctcattttga     3300

ggttgcttta tttttctaga attgttataa gaagctaaaa tagtaaactt aaaatcacaa     3360

acatgacatt gctgatagtg gctgagaaat tcagatgaga agacaaattg gttatgaatt     3420

ttgaaatatc tattatatgt aaaatgtgga tatgttcaca accttgagct attttaacac     3480

agtttaaata tagtgaggga aaactcctaa gttttactgc cctgtcctct gcaaattatg     3540

taataccagc attcttaggc gataaagaga gcagcacctc tagtaccttt aggcagatta     3600

ctttttcaag tttggggaac ttcaaaagac cataatcaac caggagctta ttataggaaa     3660

ggctgaacag aagggctagt gtattgatta cacttaacag atcatattta tccagactca     3720

gtatagctta aaattttgta tttctttatc tgagagaact gagttcccag gctaaatcac     3780

ttacctccca ccccctctcc aatttttttt ttaagagaca aggtcttgct atgttgccca     3840

ggctagagtg cagtggctat tcacaggtgc agttatagca cactacagcc tccaactctt     3900

gggttcaagc aaccctgcct cagctaacca agtagctggg actacaggtg catgctacca     3960

tgcccagtcc attttttaat cttgaaattt cttcattttt ctttcttcgg tttcttaaaa     4020

tctttgcctg aatcagaacg ctggctttta tttatttttt tatttttaat attaaatgtg     4080

cagatatgct tcgagcactt ttctaactaa tgagctctgt ggtaagaaaa aatgaactct     4140

ttcaattgag attaagtcca tatttttcaa acatcacgtt ctctattggc tttttggttt     4200

agtgtttcta aattttctcc ttctgatttt gcctgtctta tataatgagc ataggaaaat     4260

tttggaatga ggcagaaaag tatatcaaga catacttcct ggttttggat gtaagtttta     4320

aagaatggta tttttaatat ttgtacacat tctttgagca cccaggtacc caagccaata     4380

aggaaagtta attccttgca tatgactgtt atatctttag tggttgtctc cctctccctc     4440

cacagtctcc ttggcattcc atgacaagtt tgtcaaccta cacttttata tagacatatc     4500

attatttcat ggtcaagcct gtagtattaa aatgattttt ttaaaagatg taaactgtgc     4560

ttagttaatt ggttatattt tgttctgttt tttttttttt tttttttttt tttttgaggc     4620

agagtcttgt tctgttgcct gggctggagt gcagtggcgt gatcttggct cactgcaacc     4680

cccgcccccc gggttcaagt gattctcctg cctcagcctc ccgagtagct ggaattacag     4740

gcatgcgcca gcacgcccgg ctaagttttg tatttttggc agagatgggg tttcaccata     4800

ttggccaggc tggtctcaaa ctcctgacct tgtgatccgc ccacctcagc ctccgaaagt     4860

gctgggatta caggcgtgag ccaccacgtc caactgcctt attttgttct gaataaattt     4920

acagtattgg gcagcaattc tggattctag acttgagacc acagaatcaa ccatttcatg     4980

aggttgtact gtaattatac actggaatat tcaggtagtc atctttgatt tttcattcaa     5040

gtaaatatag ccataagaaa atatctgcta tacaggaaaa ccagtattaa gcaaatacca     5100

ccatccttaa cagaaacaaa aatatatata tatattattt ttaaaaatta gcattgtcat     5160

acagtacaat tcttagtgaa gtgtattgtg gaacaattta gaaacttcct ttttttcccc     5220

tagattaagg atactttcct tgacttgaga cttgtggtct tcaggaaaac tactcagaat     5280

ataatgactc ctcatcagta tcatattgta tataaataat gaaatgcatt aagaatattc     5340

acaacattga acccaggagg cggagcttgc agtgagccga gattgcgcca ctgcgctcca     5400

gcctgggcaa cagagcgaga ctccatctca aaaaaaaaaa aaaaaagaat attcacaaca     5460

ttaatgcttc tgaatagaag aactgcagga ttaagcctta aacatatatg tgcaacacgt     5520

ttaacatgct taagactcaa actcagggtt gaaaatttgg ttggggtcct ctttgtaaga     5580

taaaagttgc attatgtggt atgttctctt ccatatatgc tacagcaccc catgaattct     5640

tcaaaacttt ttacctactt gttatctgtt tatgaaaaaa agaattatgg agaagtttga     5700

gttctcagcc cttatctgta catgtctgtt aaagacaaca aaggctgcat ttaagcatta     5760

tatagataac aaattgaggc tgtctctcgt tacttagttt tactgtcttc aaaggcttgt     5820

atcattgcta gggttaagac ttatttgagg atgagttggc attgtatttt ttgtgtgtgt     5880

gggttggttt gtatttgttt cgtttttatt tttctatttt ctctcataga tttatcagta     5940

aaatataaac tcttccttag ccttaataaa ggctgctgct ttctcaaatt gagtcagata     6000

ggctcattcg gagttagatt tttaaatttg aatgaagaaa agacaacaat ttaaaggcat     6060

gtggcttcat ttccacatat atttgtgact ggattcttat ttttagcaag aggggagatc     6120

gccacaaaaa aaactttagt tcaaagaaga ctgtgcaaat cagttacctg tactttcata     6180

gtctaccatt tacattaact gttctagatt aatgactaag catggccatt accataatta     6240

catcattttt ttaaaaccac atttgttcga agtatccttt tctagtggtt agaactgtcc     6300

ctataatttg attgtccctc atatactaac cgaaagcaaa atgctctgat gagatgctta     6360

taaactatga attttttaat tcttgaaatt tttttcagtt tttatgattg ttgaatagat     6420

atgtatgttt agttccatta ttatttcact ggaagtttta aattttgaga agatgaagca     6480

gagatagaaa tccattgcag atatatgtat atttacccca tcttgcaggt ttcagttagt     6540

aaaacacaga atgataggtc ggttttaatg ttttaaaaaa aaactaaaaa actaaagtta     6600

gagaaacctt tctgtttgag ctactgtata gaaaagacaa cttttattgc attgctggtc     6660

cacatgataa atatttcaat gctgttctag actgtatgag aagtacttaa tgaaaaaagg     6720

gatacattac atttaagaat tgtatcagct aattactgtt ttaaaaaaat caactcattt     6780

ggaattcttc ggactataaa attgagcaag taaagtttgg gttttaattt tcctttgcct     6840

gaaccaagat aggaaattac ttaagagttt tttttttttt tttttttttt tttttttagg     6900

aatgaaaggt cataagccat tagaaatagt ggcattatta tgcaataaca acaccctagc     6960

taacctgctt ttgtcatctg tagcacttac aataaagaat gatgaccttc caaccctgga     7020

cactacctcg ataaagcaaa ccagagatcc tctctacact ttctatggaa gccataaaag     7080

ttgccatcaa tatatccact ttcatagttc tatactttta tactttctag acttttttat     7140

agactttatg atcagatctt tttgtctcag aggataggtt ttgcaagatt caaaggaaaa     7200

tcaaactcct tggttgttcc agctttgaag cttttgcttc agtaaatttg tttaaagaac     7260

cagatcacat accatttatc aaattcttta cttaagtcag aatactttgc agacatacat     7320

atttggaaaa caaactgttt cttgttcact agatagaatc tgtattgtag taagaaacta     7380

cttacaaggt ggctttcttt ctgctttgtt actctatgta ttactcaata atatatgtat     7440

ggtcacaggt tcctggagtt gttttatttc tttatgacag acacatgagt atgcacctct     7500

ctctaatcct ctgatgtcac tgcagcttca gtctctctca ctctgttttt gagtgccttc     7560

aaaatgccag catcctggaa cattcttttc ctgatctaaa tcctacctct gactatttca     7620

ttatccatga atattggaat tcacccatat tccaatgggc ttaactctac aaactagcta     7680

aaaccttgga caagaatttt gaccgtattt ctgttttgtt cctccatgtc atttttaggt     7740

tatattttta acttttattt atatcttatt tcttcacata tttcgtctct ctgttgaaag     7800

attttatcct tatttgactc ttcacttttt ttactttcac cagaaatttg acgttccttt     7860

aaaattaaag gtcattgaat gtcttttgaa cacctttttc tcaactgaag tcttcctgaa     7920

tgcctcccct ttctgatgaa aggatcctga gtgctgctgt tgctctgccc tgttcccatg     7980

tgcccactcc cttccgtaca cattttgcaa gactatactc tttattttag tcaaattaat     8040

ttaaaattgc tccctgggtt tctgctctct catggccctg tccctcaaaa acttctgttt     8100

actttttcta gctgttttca tctaatttgt ttaaaatgta tgatggatcc ataatatatg     8160

aaggatgtaa tgaaaaggag gttgcagtgt tttatataat atgatcgagc acctccgtga     8220

tgaaacattt agcaattggc tagtccttca cagccagagt ggaagtttgt gctgtggaca     8280

ggtcttttta ctcccttcca gttctcctcc aaaactggag aaaaaggaaa aaaaaaaaga     8340

actctttcaa atgaggagat ttgattgcat ttttttaggt gaatgaaagc ttggagttga     8400

gcatttgggc cttagtcagc atttttcctt tctgacttaa aatctcatgt ccttttcctt     8460

aaagttaata gtactcaggt ttttaagact aataaccaca caaggtgggt atctaagaag     8520

gcagctgtta atacattctc catctttcct gtctggcaac aggaaagata ttattggtga     8580

gatagtgcaa aattgtgaga attggttatg tttgatgatg aataaattca agatttttga     8640

aggcttcact gctatttggg atgggaaggt gagtttacaa aatgaaaaag gtagattttt     8700

atgttacaga aatcagtaac gggtttcttg ttgtgttaat tacctttcac ttgatttgcc     8760

atgatgtttc ttcctcatta ttgatctaga agtttgcctc ttggatagta actagtaact     8820

tagtatctac tttaaaattt gtggcttttc tcttcagggt cccaggccat aaaacaacgg     8880

agagctgtac ttgcttgtca cttggaggaa ccacatcctt gagacagcct gctgtcttgt     8940

atgtcttcag taggaaactt ctgacacaca cattcaaggg agttcctgcc cctgagaagt     9000

gttcccatag ctttccagtc gcaggttact ttcacactac gtcagcttct ctggtgagat     9060

cagggatgtt acatattact tgaaaatgat ttcataggaa gtgaggatgg ggcaagaaag     9120

gaggtagaag ctgaattttg cttaacttca gaaggaaatc tgatacttgc cttggctagt     9180

tctgatcaac taaagagcct gtgtctgtac tggatgtgcc aaagagtcaa gttgtttctg     9240

gaatatccag ctcctctgaa tgaacacagc ttcctcccta cctgtctttt atgggtgaaa     9300

agggaccgtc tgatgagcat gatagacatc ctgtacagga ctcaagactg tttcattgca     9360

tttgaaagtt ggtgggaagt attttattct gctagagctc ctaaccctcc tagaaatatc     9420

ttttcatgct ctattaattc aattcattag tttaaaaaga aacagtgtga cataattttg     9480

gtgtttactt cttaagttgt ctccccaagg gcatatatgt agcctctgaa aatgggatga     9540

tttcttctca atcttccata aatttgaata tgcattttat tcatttcttg acatgggctg     9600

tgtgactgtt ttccatcagc agttctggct ttgtccacaa gggagcaata aagtacgtta     9660

gctttattct caaccttcta aagaaagatc ccacttttaa atctcttctg gaatagcctc     9720

ttagctcaaa gcttattcat gtattttgat tatttaagaa attttccctt attacaaagt     9780

ccagtcgtcg ttcatccctc atgatgccaa gcaatgattg atgtgtgggt gtggagtcct     9840

tgtgggtcag gcatcttaat taattagact ttttacatat tgatgatccc cagattgaaa     9900

gccaggacct tcccataggg gcgcctttgt gtgctaaagg cagagcaggc aggcttctcc     9960

actcctatct cctccgcagg ccaccaccat cacatctata ggaggaacaa gagcactggg    10020

ggaactctgg agtatgagta aggaaatgct tctcaccttc tctgctccaa agagatatct    10080

gttacatcag ggaacaagtc ctctaggtca ggcacttcct cctgaccagt gcaacgggca    10140

ctccaggtta gaaactgtgt gtgctccctc tctgtcagtt acttgtctaa gggctcctat    10200

ccgtggtcat cagctctctg gccatgagtt ctgtttgtgc ttattgcagc agcatcttca    10260

caacaaacag gtcagtaatc aacctgggaa gggaaaagac gacagtaaat attaccccct    10320

gtagagccgg gaggcattta cacctggaat ggccttctta actgatttct gcctggccac    10380

ctcaccccca gccaagtctg aacctgagca ataccaggca cagagaggtg tctacttgta    10440

actccaacac ttgacaaaaa acaaaactga agctgtgatt ggtttaggca gcaagtggcc    10500

aggtgcaact tgtttgtttt tatttttgtt ttccccaaca gtactgagat cacttgcact    10560

tttcctcatt tcttaagaaa atccagtttg cttgccatga cttgtttagc gttaggttta    10620

caaagcttgt tgttgaatgt tgaatatttg tccaaaggag tttgacaaaa tagaagctgc    10680

ttggtccctg ttctgcctgc taggtcataa ggatgaaggc catgtggctg gggtacttat    10740

gtcaagtcca gaatggggca gtgtccctct cctacctctc tgcggagacg caattgaagg    10800

tcaagtagac tcagtgtagg gcaggcagct gtcatgctgc aaagaagttt agaggagtct    10860

ttgggttggg gaggtgacag gtaggtagga caggatctct taagatggga aagatactgg    10920

ggagaggagg gctgcttggc cccagggaac tgcagtgagg tggaactgag ctccgctcct    10980

gaatctccaa aggagcccat gctgcccggc ttccctgagt cattttttcc agcatcctgt    11040

cagatccctc aatgtactga tttccccctt gtgttaacta taccgatatt atttttttag    11100

caattgaaat gcactttttt atttcaactc aatcatgatt ttaagtataa aaaatttata    11160

gattgttaaa actacttttt tgtgtatttt taaccactca atgtagcatt gtatatttta    11220

ttcttgtgag actctggtac aggtgtgccg cctaatgatt tttctgagat gctgggcctt    11280

tggatgtgta cggtaaccaa cttaatgcta atgttcaaag taaaaaaaaa aaaaaaaagc    11340

agccata                                                              11347


<210>  1437
<211>  3979
<212>  DNA
<213>  homo sapiens

<400>  1437
gaacccgcct gtcagccagc ctttcgagct aattagctca gcatacaaca aagataagtg       60

agcctgggaa gagggccccc tgaggggtct ttagattctg ggaaatgtct gattggcaga      120

tgttaaaagg gattccttgg taatccagtg catcaatgag ctgcagaaat tcagcccagg      180

actgcaagaa ttcaggcatg aggacactct gtacaggagg ctcacacagg cagacccaag      240

atggacagaa ccttggaatc tctgagacac atcattgccc aagtcttgcc tcacagagat      300

ccggctctag tcttcaaaga cttgaacgtt gtgtcaatgt tacaggaatt ttgggaaagc      360

aagcagcagc agaaggctgc attcccaagt gaaggtgtgg tggtctatga gtcactgcca      420

gctcctgggc ctccctttgt gagttacgtg accctcccag ggggaagctg ttttggcaac      480

tttcagtgct gcttaagtag agccgaggcc aggcgggatg cagctaaagt ggccctgatc      540

aactccctct tcaatgagct gccctctcgc aggatcacca aggaattcat tatggaaagt      600

gttcaggaag cagtagcctc caccagcggc accttagatg atgcagatga ccccagcacc      660

agtgttgggg cctatcacta catgctggag tcaaacatgg ggaagactat gctggagttt      720

caggagctga tgaccatttt ccaactattg cactggaatg gaagcctaaa agcccttcgt      780

gaaacaaagt gttcccgaca ggaagtcatc tcctactatt ctcagtattc tctagatgaa      840

aagatgcgca gccacatggc cctggactgg atcatgaagg agcgggactc accaggaatt      900

gtctctcaag agctacgaat ggccctgagg cagttggagg aagccaggaa agcaggacaa      960

gaactacggt tttacaaaga aaagaaagaa atattgagct tagccctgac tcagatctgc     1020

agtgaccctg acacttcctc acccagtgat gatcagctga gccttacggc cctgtgtggc     1080

tatcactagc aaggccaagc cccgggtacc ctcagtgatg gcagaggcca gattaacatt     1140

aggaatctca gtgcagaggt cctcagaggc tccagcatct ctagtactac ctgaaggctc     1200

tcctaaccct ctccacacat tccatttaca gagtatgaga gtcgtaggac ccttacaaga     1260

cccaacaagc cactcgatgc atttttctat cacattctca atagttccag ctcaggatga     1320

aaggatagac acaaaattgt ttgaaaaaca ttttccaggc ctggctccaa cctaaagcct     1380

gactgtcacg tgccttgctt gattttatat atattgtttc aagaatagtc caatatagca     1440

ttccccaaat gaacagcagc cagaattagg tgaagtagca tgatagcagt gtttaaaaat     1500

acttaggatt aaataaataa tatggattgt tttaaaaaat atccaaggat cagagtctct     1560

ttctaagctt tgtaagctaa gcaatagttt atgtcctact agatacactg caaactacag     1620

tggggatttt atctggacat cccaccatca aagatcttga aatagtaata gtatgaaaat     1680

actagataaa attaatgttt aaaatgtttt tgtaacaata atttttaaaa cccacactct     1740

tccatatatg gggataaata tcacctagaa aagtagcctc actcttattc ctcaagaatt     1800

aatatccaat gtttatgagt cttgcaatca attttgttca tttttaattt gcaaatcgat     1860

aacctgaact aatttgttct tattttttgc cactgcaaac atatatctac agagagaaaa     1920

attaatggca ttttaaaggt taaaacattt tgaaaaatta ttagcatgta acaaagaatg     1980

cttgcatttg attagtttca ccagcatttg agagaaggac cctttagctc tgtttgttgt     2040

tcaagaacat aagcaaccag tagctcaaat gtagtatcat tattaagttt aagtcactgg     2100

aatcttcttt aaaggaagga taagacattg ccatctctat ttaactcatc catatgggtc     2160

aatcaactga ttagaaaatc aaaaaacaat aaaaactttt tttttttttt tttttttagt     2220

agagacggga tttcatcatg ttgcccaggc tggtcttgaa ctcctgggct caagccatct     2280

gcctgcctcc acctcccaaa atgctgagat tacaggtgtg agccaccatg cctggcctaa     2340

actaattttt agatagttcc tggtcactca aatttaagaa tgtcagcaat gtcaatttta     2400

aatgctcata ggtctttcca tatctgtaac atgaaaatga ttattctgca ttttattcag     2460

tagtccaaat taaagaaaat gtttttctca atttaaaata atttcttttt cttttgttta     2520

tgcaagtgca tacatgcttc actgaaagca aaaccattat aattacatta aagtttataa     2580

aatatgatat tttaacctca tatctaataa gtatgtacaa aggtaaccat cactccttaa     2640

atccacatga aaactactgt aactgatcat gtattttgga attagacttg ataataaaag     2700

attatcatgt atcacatatc tcacaccagg ggaacaatta gctacataat tgtcatacct     2760

taatatcttt taaaggtaac agtaattttc aacacatttt attttaaaat attattttaa     2820

caaaagttac attcctctcc acaatgaggc taaatgtcac ccacgaaaga actttattcc     2880

cttatattcc tgaaaagaaa tcagaattaa catttttatg ttgaataaat tttaaaattt     2940

aggaaatgtt ctatttaaag ttaatttctt tcataaagcc attactcttt acattgtcat     3000

ttccaaaaag ccacaatttc ccatgctgga tgtgatgaaa gttaggcaca cctttactgc     3060

attagcagcc tttgacaatg acttcctcaa actgacacca tcttaattag atgcagggac     3120

agggatcaga tgggacaata tcaaatttac tttgtgccct acaagttaaa aactgcaccc     3180

attctgtaaa ttgaatatag aggttctccc ttggccactg tcagcttttc ttgactggcc     3240

aaaactgccc attcttcctg gaatggtatg aaagcttcag caaaataaat aaaagtcaga     3300

atctttgctg gtccctttaa tgctgatttg atagtaaatc aatttcagct gagacataag     3360

ggctgtcagt ctatcatata aacatcttta actatagcct agagaaaaga gggttgaaga     3420

gcaaagcaga tttttttttt ccttttctat atcttgttct gaacaacaca ctgtgataaa     3480

ggggactaga gtggaagatt ccctatttaa acacatgaag ctctgggtcc tagccttttt     3540

tggttataag ccctttgaga atctgataaa agctgtggat catctcctag gaaaatagaa     3600

caaaacatac atattcacat tacacagttc cagagtatgt ggacccccca aagtccagag     3660

attgccctag gggatcttta gattcttgtt tagaactgtt gattttgaac acaacataca     3720

ctgtcaaact ttacatcagg gatccaacat aactcagaca tagcccaggt agcctgtttc     3780

taacacaact gtcataatcc tgaaatccaa aattgcactg tgtttgacat gagatagttt     3840

aagttccaca aaatccaaat ttaccatatt attgttttta aaaaagcagt ttagagcaaa     3900

ctgtcactaa acttggataa atgggtcaga aagtacagat ttaataaagt cgtacctcta     3960

atgttcaaaa aaaaaaaaa                                                  3979


<210>  1438
<211>  1706
<212>  DNA
<213>  homo sapiens

<400>  1438
gaagaagttg gttcttgtct cgaatacttt tcctcccgtg ccccgcccct tgaatcagag       60

gcggctgtct cgtgcggcta gagcagggcc agtagagttc ggggcagctg tcaaaaacga      120

gacggggagg cttttcttcc cgggggtgga ggagggaagg agggaggtgt ccttttttcc      180

atctgttgca gtttccgaac caaacgcacc ctcgccagcc ccgggaagaa aggcccaagg      240

gagaaacctg gggcgctcgg ctggtgcccc caccgccggg cgagggatgc gggcggtccg      300

tgcgcggcag gcggaaagga tcgtgtttct ggacccggcc accccccgcg tccgcaccgc      360

cgcccccgag ggacgagtga cagcggccgc cgcgctcggt ccagtcttcc cggctggaag      420

gtattgttgc agcatctggc agtgagactg aggatgagga cagcatggac attcccttgg      480

acctttcttc atccgctggc tcaggcaaga gaaggagaag gggcaaccta cccaaggagt      540

ctgtgcagat tcttcgggat tggctgtatg agcaccgtta caatgcctat ccttcagagc      600

aagaaaaagc gttgctgtcc cagcaaacac acctgtctac gctacaggtc tgtaactggt      660

tcatcaacgc ccgccgcagg ctcctccctg acatgctgag aaaggatggc aaagatccaa      720

atcagttcac aatttcccgc cgtggggcca agatttctga aacgagctct gtggagtccg      780

tgatgggcat caaaaacttc atgccagctc tagaggagac cccatttcat tcctgtacag      840

ctgggccaaa cccaacccta gggaggccac tgtctcctaa gccgtcatcc ccgggatcag      900

ttttggctcg tccatcagtg atctgccata ccactgtgac tgcattgaaa gatgtccctt      960

tctctctctg ccagtcggtc ggtgtgggac aaaacacaga tatacagcag atagcggcca     1020

aaaacttcac agacacctct ctcatgtacc cagaggacac ttgtaaatct ggaccaagta     1080

cgaatacaca gagtggtctt ttcaacactc ctccccctac tccaccggac ctcaaccagg     1140

acttcagtgg atttcagctt ctagtggatg ttgcactcaa acgggctgca gagatggagc     1200

ttcaggcaaa acttacagct taacccattt tcaagcaaaa cagttctcag aaatgtcatg     1260

attgccgggg tgaaggcaag agatgaattg cattatttta tatatttttt attaatattt     1320

gcacatggga ttgctaaaac agcttcctgt tactgagatg tcttcaatgg aatacagtca     1380

ttccaagaac tataaactta aagctactgt agaaacaaag ggttttcttt tttaaatgtt     1440

tcttggtaga ttattcataa tgtgagatgg ttcccaatat catgtgattt tttttttcct     1500

ccccttccct ttttttgtta ttttttcaga ctgtgcaata cttagagaac ctatagcatc     1560

ttctcattcc catgtggaac aggatgccca catactgtct aattaataaa ttttccattt     1620

tttttcaaac aagtatgaat ctagttggtt gatgcctttt ttttcatgac ataataaagt     1680

attttcttta aaaaaaaaaa aaaaaa                                          1706


<210>  1439
<211>  6517
<212>  DNA
<213>  homo sapiens

<400>  1439
aggttatgta agggtttgct ttcaccccat tcaaaaggta cctcttcctc ttctcttgct       60

ccctctcgcc ctcattcttg tgcctatgca gacatttgag tagaggcgaa tcactttcac      120

ttctgctggg gaaattgcaa cacgcttctt taaatggcag agagaaggag aaaacttaga      180

tcttctgata ccaaatcact ggaccttaga agttgatatt cactgatgga ctccaaagaa      240

tcattaactc ctggtagaga agaaaacccc agcagtgtgc ttgctcagga gaggggagat      300

gtgatggact tctataaaac cctaagagga ggagctactg tgaaggtttc tgcgtcttca      360

ccctcactgg ctgtcgcttc tcaatcagac tccaagcagc gaagactttt ggttgatttt      420

ccaaaaggct cagtaagcaa tgcgcagcag ccagatctgt ccaaagcagt ttcactctca      480

atgggactgt atatgggaga gacagaaaca aaagtgatgg gaaatgacct gggattccca      540

cagcagggcc aaatcagcct ttcctcgggg gaaacagact taaagctttt ggaagaaagc      600

attgcaaacc tcaataggtc gaccagtgtt ccagagaacc ccaagagttc agcatccact      660

gctgtgtctg ctgcccccac agagaaggag tttccaaaaa ctcactctga tgtatcttca      720

gaacagcaac atttgaaggg ccagactggc accaacggtg gcaatgtgaa attgtatacc      780

acagaccaaa gcacctttga cattttgcag gatttggagt tttcttctgg gtccccaggt      840

aaagagacga atgagagtcc ttggagatca gacctgttga tagatgaaaa ctgtttgctt      900

tctcctctgg cgggagaaga cgattcattc cttttggaag gaaactcgaa tgaggactgc      960

aagcctctca ttttaccgga cactaaaccc aaaattaagg ataatggaga tctggttttg     1020

tcaagcccca gtaatgtaac actgccccaa gtgaaaacag aaaaagaaga tttcatcgaa     1080

ctctgcaccc ctggggtaat taagcaagag aaactgggca cagtttactg tcaggcaagc     1140

tttcctggag caaatataat tggtaataaa atgtctgcca tttctgttca tggtgtgagt     1200

acctctggag gacagatgta ccactatgac atgaatacag catccctttc tcaacagcag     1260

gatcagaagc ctatttttaa tgtcattcca ccaattcccg ttggttccga aaattggaat     1320

aggtgccaag gatctggaga tgacaacttg acttctctgg ggactctgaa cttccctggt     1380

cgaacagttt tttctaatgg ctattcaagc cccagcatga gaccagatgt aagctctcct     1440

ccatccagct cctcaacagc aacaacagga ccacctccca aactctgcct ggtgtgctct     1500

gatgaagctt caggatgtca ttatggagtc ttaacttgtg gaagctgtaa agttttcttc     1560

aaaagagcag tggaaggaca gcacaattac ctatgtgctg gaaggaatga ttgcatcatc     1620

gataaaattc gaagaaaaaa ctgcccagca tgccgctatc gaaaatgtct tcaggctgga     1680

atgaacctgg aagctcgaaa aacaaagaaa aaaataaaag gaattcagca ggccactaca     1740

ggagtctcac aagaaacctc tgaaaatcct ggtaacaaaa caatagttcc tgcaacgtta     1800

ccacaactca cccctaccct ggtgtcactg ttggaggtta ttgaacctga agtgttatat     1860

gcaggatatg atagctctgt tccagactca acttggagga tcatgactac gctcaacatg     1920

ttaggagggc ggcaagtgat tgcagcagtg aaatgggcaa aggcaatacc aggtttcagg     1980

aacttacacc tggatgacca aatgacccta ctgcagtact cctggatgtt tcttatggca     2040

tttgctctgg ggtggagatc atatagacaa tcaagtgcaa acctgctgtg ttttgctcct     2100

gatctgatta ttaatgagca gagaatgact ctaccctgca tgtacgacca atgtaaacac     2160

atgctgtatg tttcctctga gttacacagg cttcaggtat cttatgaaga gtatctctgt     2220

atgaaaacct tactgcttct ctcttcagtt cctaaggacg gtctgaagag ccaagagcta     2280

tttgatgaaa ttagaatgac ctacatcaaa gagctaggaa aagccattgt caagagggaa     2340

ggaaactcca gccagaactg gcagcggttt tatcaactga caaaactctt ggattctatg     2400

catgaagtgg ttgaaaatct ccttaactat tgcttccaaa catttttgga taagaccatg     2460

agtattgaat tccccgagat gttagctgaa atcatcacca atcagatacc aaaatattca     2520

aatggaaata tcaaaaaact tctgtttcat caaaagtgac tgccttaata agaatggttg     2580

ccttaaagaa agtcgaatta atagctttta ttgtataaac tatcagtttg tcctgtagag     2640

gttttgttgt tttatttttt attgttttca tctgttgttt tgttttaaat acgcactaca     2700

tgtggtttat agagggccaa gacttggcaa cagaagcagt tgagtcgtca tcacttttca     2760

gtgatgggag agtagatggt gaaatttatt agttaatata tcccagaaat tagaaacctt     2820

aatatgtgga cgtaatctcc acagtcaaag aaggatggca cctaaaccac cagtgcccaa     2880

agtctgtgtg atgaactttc tcttcatact ttttttcaca gttggctgga tgaaattttc     2940

tagactttct gttggtgtat cccccccctg tatagttagg atagcatttt tgatttatgc     3000

atggaaacct gaaaaaaagt ttacaagtgt atatcagaaa agggaagttg tgccttttat     3060

agctattact gtctggtttt aacaatttcc tttatattta gtgaactacg cttgctcatt     3120

ttttcttaca taatttttta ttcaagttat tgtacagctg tttaagatgg gcagctagtt     3180

cgtagctttc ccaaataaac tctaaacatt aatcaatcat ctgtgtgaaa atgggttggt     3240

gcttctaacc tgatggcact tagctatcag aagaccacaa aaattgactc aaatctccag     3300

tattcttgtc aaaaaaaaaa aaaaaaaagc tcatattttg tatatatctg cttcagtgga     3360

gaattatata ggttgtgcaa attaacagtc ctaactggta tagagcacct agtccagtga     3420

cctgctgggt aaactgtgga tgatggttgc aaaagactaa tttaaaaaat aactaccaag     3480

aggccctgtc tgtacctaac gccctatttt tgcaatggct atatggcaag aaagctggta     3540

aactatttgt ctttcaggac cttttgaagt agtttgtata acttcttaaa agttgtgatt     3600

ccagataacc agctgtaaca cagctgagag acttttaatc agacaaagta attcctctca     3660

ctaaacttta cccaaaaact aaatctctaa tatggcaaaa atggctagac acccattttc     3720

acattcccat ctgtcaccaa ttggttaatc tttcctgatg gtacaggaaa gctcagctac     3780

tgatttttgt gatttagaac tgtatgtcag acatccatgt ttgtaaaact acacatccct     3840

aatgtgtgcc atagagttta acacaagtcc tgtgaatttc ttcactgttg aaaattattt     3900

taaacaaaat agaagctgta gtagcccttt ctgtgtgcac cttaccaact ttctgtaaac     3960

tcaaaactta acatatttac taagccacaa gaaatttgat ttctattcaa ggtggccaaa     4020

ttatttgtgt aatagaaaac tgaaaatcta atattaaaaa tatggaactt ctaatatatt     4080

tttatattta gttatagttt cagatatata tcatattggt attcactaat ctgggaaggg     4140

aagggctact gcagctttac atgcaattta ttaaaatgat tgtaaaatag cttgtatagt     4200

gtaaaataag aatgattttt agatgagatt gttttatcat gacatgttat atattttttg     4260

taggggtcaa agaaatgctg atggataacc tatatgattt atagtttgta catgcattca     4320

tacaggcagc gatggtctca gaaaccaaac agtttgctct aggggaagag ggagatggag     4380

actggtcctg tgtgcagtga aggttgctga ggctctgacc cagtgagatt acagaggaag     4440

ttatcctctg cctcccattc tgaccaccct tctcattcca acagtgagtc tgtcagcgca     4500

ggtttagttt actcaatctc cccttgcact aaagtatgta aagtatgtaa acaggagaca     4560

ggaaggtggt gcttacatcc ttaaaggcac catctaatag cgggttactt tcacatacag     4620

ccctccccca gcagttgaat gacaacagaa gcttcagaag tttggcaata gtttgcatag     4680

aggtaccagc aatatgtaaa tagtgcagaa tctcataggt tgccaataat acactaattc     4740

ctttctatcc tacaacaaga gtttatttcc aaataaaatg aggacatgtt tttgttttct     4800

ttgaatgctt tttgaatgtt atttgttatt ttcagtattt tggagaaatt atttaataaa     4860

aaaacaatca tttgcttttt gaatgctctc taaaagggaa tgtaatattt taagatggtg     4920

tgtaacccgg ctggataaat ttttggtgcc taagaaaact gcttgaatat tcttatcaat     4980

gacagtgtta agtttcaaaa agagcttcta aaacgtagat tatcattcct ttatagaatg     5040

ttatgtggtt aaaaccagaa agcacatctc acacattaat ctgattttca tcccaacaat     5100

cttggcgctc aaaaaataga actcaatgag aaaaagaaga ttatgtgcac ttcgttgtca     5160

ataataagtc aactgatgct catcgacaac tataggaggc ttttcattaa atgggaaaag     5220

aagctgtgcc cttttaggat acgtggggga aaagaaagtc atcttaatta tgtttaattg     5280

tggatttaag tgctatatgg tggtgctgtt tgaaagcaga tttatttcct atgtatgtgt     5340

tatctggcca tcccaaccca aactgttgaa gtttgtagta acttcagtga gagttggtta     5400

ctcacaacaa atcctgaaaa gtatttttag tgtttgtagg tattctgtgg gatactatac     5460

aagcagaact gaggcactta ggacataaca cttttggggt atatatatcc aaatgcctaa     5520

aactatggga ggaaaccttg gccaccccaa aaggaaaact aacatgattt gtgtctatga     5580

agtgctggat aattagcatg ggatgagctc tgggcatgcc atgaaggaaa gccacgctcc     5640

cttcagaatt cagaggcagg gagcaattcc agtttcacct aagtctcata attttagttc     5700

ccttttaaaa accctgaaaa ctacatcacc atggaatgaa aaatattgtt atacaataca     5760

ttgatctgtc aaacttccag aaccatggta gccttcagtg agatttccat cttggctggt     5820

cactccctga ctgtagctgt aggtgaatgt gtttttgtgt gtgtgtgtct ggttttagtg     5880

tcagaaggga aataaaagtg taaggaggac actttaaacc ctttgggtgg agtttcgtaa     5940

tttcccagac tattttcaag caacctggtc cacccaggat tagtgaccag gttttcagga     6000

aaggatttgc ttctctctag aaaatgtctg aaaggatttt attttctgat gaaaggctgt     6060

atgaaaatac cctcctcaaa taacttgctt aactacatat agattcaagt gtgtcaatat     6120

tctattttgt atattaaatg ctatataatg gggacaaatc tatattatac tgtgtatggc     6180

attattaaga agctttttca ttatttttta tcacagtaat tttaaaatgt gtaaaaatta     6240

aaaccagtga ctcctgttta aaaataaaag ttgtagtttt ttattcatgc tgaataataa     6300

tctgtagtta aaaaaaaagt gtctttttac ctacgcagtg aaatgtcaga ctgtaaaacc     6360

ttgtgtggaa atgtttaact tttatttttt catttaaatt tgctgttctg gtattaccaa     6420

accacacatt tgtaccgaat tggcagtaaa tgttagccat ttacagcaat gccaaatatg     6480

gagaaacatc ataataaaaa aatctgcttt ttcatta                              6517


<210>  1440
<211>  4746
<212>  DNA
<213>  homo sapiens

<400>  1440
agcacaaccg cctaagcggc ggaactctgg agagtgcgga acctaggatc ctaggaaact       60

gaaggcaacg gaacctgggg gcgatggaat ccgggagcgg tggaacccgg agcctgtaga      120

acttgaatct agaggaacct gacagcggcg ccgagggggc cacccggact ctgtttggaa      180

cggaagcaca gtgtccgccg cttcctggtt gcgggtcagc gcccaggtcc tgggctggcc      240

gccgggatgt tgccctacac agtgaacttc aaggtgtcgg cgcgcaccct cacgggggcc      300

ctcaacgccc acaacaaggc ggcggtggac tggggctggc aaggtttaat tgcttatgga      360

tgtcattcac ttgtggtagt gattgattcc attactgccc aaactcttca agttttagaa      420

aagcataaag ctgatgttgt aaaggttaaa tgggccaggg aaaactatca ccataacatt      480

ggctcaccat attgcttacg gttagcttct gctgatgtca atgggaagat catcgtctgg      540

gatgtagcag caggagtagc tcagtgtgag atccaagagc atgccaagcc tatccaggat      600

gttcagtggt tgtggaatca agatgcttcc cgcgatttac tgcttgctat ccacccgcca      660

aattacattg tgctctggaa tgccgacact ggcaccaaac tatggaagaa gagctatgca      720

gataacattc tttctttttc ttttgaccct tttgatccct cacatttaac tttgcttacc      780

agcgagggta ttgttttcat ctcagacttc tccccatcca agcctccctc aggccctggg      840

aaaaaagttt acatatccag cccacactct agcccagctc ataacaagct ggccacagcc      900

acaggtgcca agaaagctct aaataaagta aaaattttaa tcactcaaga gaaacctagt      960

gctgaattca taactctcaa tgattgcctt cagttggcat acctgccttc aaaaaggaat     1020

cacatgttgt tgctctatcc tcgagagatt ttaatccttg accttgaggt gaatcagacg     1080

gtgggtgtga ttgcaataga acgcacagga gttccatttt tacaggtaat accctgcttt     1140

cagcgtgatg gtttattttg tctacatgaa aatggttgta taactttacg tgttcgaaga     1200

tcttataata acatttttac cacttcaaat gaggaaccag atccagatcc agttcaggag     1260

cttacctatg atttacgaag ccagtgtgat gcaatcaggg tgacaaaaac cgtccgtccc     1320

ttcagtatgg tgtgctgtcc tgtcaatgag aatgcagccg ccctcgtagt gagtgatggc     1380

agggtcatga tatgggaact caagtctgca gtttgtaatc gaaattcacg gaacagtagt     1440

tctggtgtgt cacctttata ttcaccagtg tctttctgtg gaattcctgt aggagtgcta     1500

cagaataaac tcccagacct ttccttagat aacatgattg ggcaaagtgc aattgctggg     1560

gaagaacatc ccagaggttc aattctgcgg gaagtgcacc tcaagttcct gctgacggga     1620

ctgctttcag gactgcccgc accacagttt gctattcgta tgtgtccacc gttgaccaca     1680

aaaaacatca agatgtatca gccactgctg gctgttggta caagtaatgg ttctgtcctg     1740

gtgtaccatc tcaccagtgg tctgctacac aaagagttaa gcatccactc atgtgaagtc     1800

aagggtattg aatggacaag tttgactagt tttctttctt ttgctacctc aacaccaaac     1860

aatatgggat tagtgagaaa tgaacttcaa ctggttgatc ttccaacagg taggagcatt     1920

gcttttcgtg gtgaaagagg caatgatgaa tctgccatcg aaatgattaa agtatctcat     1980

ttgaagcagt atttggcagt cgtattcaga gataaacccc tggagctatg ggatgttagg     2040

acttgtaccc ttcttagaga gatgtccaaa aacttcccta caataactgc tttggagtgg     2100

tcaccatctc acaacttgaa gagcctgaga aagaagcaac ttgcaactcg agaggccatg     2160

gcccgccaga ccgtagtctc agacacagag ctgagtattg ttgaatcatc tgtgatcagc     2220

ttgctgcagg aggcagaaag taaatctgaa cttagtcaga acatctctgc ccgggaacat     2280

tttgtattta ccgatattga tggccaagtg tatcatctca ctgttgaagg aaactcagta     2340

aaagacagtg ctcggattcc accagatgga agtatgggta gtattacctg catcgcttgg     2400

aaaggtgata cattagtgct tggagatatg gatggaaatt taaatttctg ggacttgaaa     2460

ggcagagtat ccagaggaat acccacacac cgaagttggg tgaggaagat tcgttttgct     2520

cctggtaaag gaaatcaaaa attaatagca atgtacaatg atggagctga agtgtgggat     2580

actaaagagg ttcagatggt gagcagttta agaagtggca gaaatgtgac ctttcgtata     2640

ttggatgtgg actggtgtac gtcagataaa gtgatcttgg cctcagatga tgggtgcatc     2700

agagtcctag agatgtctat gaagtctgcg tgctttagaa tggatgaaca agagttaacc     2760

gagcctgtgt ggtgccccta tctccttgtt ccaagggcct ctcttgcctt gaaagccttc     2820

ttattacacc agccttggaa tggacagtat tctttggaca tttctcatgt tgactatcca     2880

gaaaatgaag aaataaagaa tctcctccaa gaacagttga attcattgtc taatgacata     2940

aagaaactgt tgcttgatcc agaattcact ctcttgcaga ggtgcctgct tgtttcaagg     3000

ctctatggtg atgaatcgga gctgcacttc tggactgtcg ctgcccacta cctgcacagc     3060

ttatcccagg aaaagtcagc cagcacaaca gctcctaaag aagctgctcc tcgagacaaa     3120

ctgagcaacc cactggatat atgctatgac gtgctctgtg aaaatgccta ctttcagaaa     3180

tttcagctag aaagggttaa tctgcaggaa gtgaaacggt caacttatga tcatacaagg     3240

aaatgtacag accagctact gctcttgggt caaacagaca gagctgtgca gttgctgttg     3300

gaaacaagtg cagataacca gcattattac tgtgattcac tgaaagcctg tttagtcact     3360

actgtcacct cgtcaggccc ctctcagagc accattaagt tggtggcaac gaatatgatt     3420

gccaatggca aattggcaga gggcgttcag ttgctctgcc tgatagataa ggctgcagac     3480

gcctgccgct acctgcagac atacggcgag tggaatcggg ctgcatggct ggcaaaagtc     3540

cgtttgaatc ctgaggagtg tgccgatgtt ttaaggcggt gggttgacca cctttgttct     3600

ccacaagtca atcagaaatc aaaggctctc ctggttctcc tctctctggg ctgctttttt     3660

agcgtggcag agacgcttca cagcatgaga tactttgata gagcagcctt atttgtggaa     3720

gcttgcctca agtatggagc atttgaagtc actgaggaca cagagaaact catcactgct     3780

atatatgcag attatgcccg gagtttgaag aacctcggtt ttaagcaggg agcagttctc     3840

tttgcttcaa aagccggagc agctggcaaa gacttattga atgagcttga gtcccccaag     3900

gaagaaccca ttgaagagtg acagcttaat aaatgccagg gaatctgacc tggaaggcag     3960

atgggagggg gctggtctgg ctgtggccac cgtcacagtc caggatgaag aggagtacag     4020

ggtcctgtga gctgtttgac cactgttcta agactatgtg tgcccaaaag cacataagca     4080

tctatgttga gagtaagttt gtatcctgcg ttggtctcag aaagaacgtg aatgcttaag     4140

attttgaaag tacataatat tttatacttt gggagagagc tttaagagtc cctggaaata     4200

ctttttaatt tttttaactt aaaattcaag agactgaatc acttttctca ttgattaaat     4260

gtaaagatta ttgagaaacc tatagtaaat gaaatttgtg agatgttttc tcaaatatat     4320

gctgtgcctg tacttatata cagtctttca agagagatac aaacaaggca gaaacattta     4380

aactagtatt aaaggtagtt taccaaagca ttttttgttt tcttaccttg aaaacacaga     4440

accgttaatt ccttggttta agcagttgct aagttttgta attttaggct cagaggacca     4500

taggaggttt taagatttat gtttagtccg ataggtgagg tctttgatat tttgaatttt     4560

aactcctttt atgatacatc acagtaacct catttttgaa gtctttcttt gtactttaat     4620

gttctctctg ttctaatagt tgaagtatga gatgtaacta ttataaactg ttgctgaaaa     4680

cataaatgtc tgtaacttac aaacatgata aataaattaa aaattccatc caggaaaaaa     4740

aaaaaa                                                                4746


<210>  1441
<211>  2384
<212>  DNA
<213>  homo sapiens

<400>  1441
attcctcgtt agggcaggcg cggccccttc ggctccgagc tgaccctgat cagggccgag       60

ttgtctcggc ggcgctgccg aggcctccac ccggggaggg tggttaccgc tgaggagctg      120

cagtctctgt caagatgata gaggtactga caacaactga ctctcagaaa ctgctacacc      180

agctgaatgc cctgttggaa caggagtcta gatgtcagcc aaaggtctgt ggtttgagac      240

taattgagtc tgcacacgat aatggcctca gaatgactgc aagactaagg gactttgaag      300

taaaagatct tcttagtcta actcagttct ttggctttga cacagagaca ttttctctag      360

ctgtgaattt actggacaga ttcctgtcta aaatgaaggt acagcccaag caccttgggt      420

gtgttggact gagctgcttt tatttggctg taaaatcaat agaagaggaa aggaatgtcc      480

cattggcaac tgacttgatc cgaataagtc aatataggtt tacggtttca gacttgatga      540

gaatggaaaa gattgtattg gagaaggtgt gttggaaagt caaagctact actgcctttc      600

aatttctgca actgtattat tcactccttc aagagaactt gccacttgaa aggagaaata      660

gcattaattt tgaaagacta gaagctcaac tgaaggcatg tcattgcagg atcatatttt      720

ctaaagcaaa gccttctgtg ttggcattgt ctatcattgc attagagatc caagcacaga      780

agtgtgtaga gttaacagaa ggaatagaat gtcttcagaa acattccaag ataaatggca      840

gagatctgac cttctggcaa gagcttgtat ccaaatgttt aactgaatat tcatcaaata      900

agtgttccaa accaaatgtt cagaagttga aatggattgt ttctgggcgt actgcacggc      960

aattgaagca tagctactac agaataactc accttccaac aattcctgaa atggtccctt     1020

aactggatta ttacagcacc aaaaaacttc tctgaagcct ttctccacaa ccttgttcta     1080

tggattccat aatgttacaa tggatttaag ctatgaagcc tcaaaacatc acgagataag     1140

catgatggtc tcagacttgg gaaaactgcc taatattatg ctgtagtgga attatgttta     1200

gatttgaatt catctgtgaa gcattcaaat caaagctaaa agcctaaatg tgaaatgcta     1260

atgacaagcc tgagaaggta aactgtgaat cttcatttct atcattgatc taactttaga     1320

tattggatca atatatttag gtggtattga aaatgctatt ggaggagtca cactaatact     1380

atcaactatc agtcttccca cagcttcaat cactgtcatt attctaatcc tactcctact     1440

taaattttaa gttatgaggt ttatgtcaaa agcaacattt cacaaatgta cttttaaggc     1500

ataataaggg ttaacattct aggcagtata aacacacccc ataatgcaag taataggtaa     1560

tctagagatg tggactttat tgctatatgg gaattacatt taaatttgag ggcattttat     1620

ataaagaaaa atacagacct ataaagtttg gcatattcat taagttatct tttaatattt     1680

ttttctagaa aacaggtgac atttgtatct acgataaaaa tttttataca gaacctactg     1740

cctcaaactg aatcccatca agaaaactag tttctattgt attagtaact caaaataaat     1800

tatcacttcg aaaacttgct ttcccacact aaggtaagtt cagactagat tgaacactcc     1860

agaatttttt actacagact gtttttaagt tagaagtgat ggcaatttta taaatagaga     1920

atatacttcc actgatgccc ttactgtgcc aaaacaaaaa tcttaagaaa agcaagtaga     1980

caccttcata actatgaatg aagctgctga agtagtgttt aggatcctcc atggcagtta     2040

gtgaatgtaa gaagtacagt gttaaagtgt tgtaaacagt tactcagtgc aatgtatagc     2100

ctgagtctat ccatgatggc tatatccaat ttgacatcac gttatggatc agtacacaat     2160

gaaaaaccaa agaaccacag tatatcttat tcttaacttt tgtaaaccat gttttatggg     2220

taacttttta gttttcccaa aaggctgata aatttcaata ttttgaatac atcattgtta     2280

attttgagtt ggcagaggta aactaaccaa ctaccattat gttttagtac taagggatat     2340

acctttcaat aaagttaatg aaattcaaaa aaaaaaaaaa aaaa                      2384


<210>  1442
<211>  5489
<212>  DNA
<213>  homo sapiens

<400>  1442
gaaactctta acaaaaacaa ggggctcggg gaggtttccg ctgaggcggc gggggtgcgg       60

cggtgggctg gtcttccgcg gccggcgttg cgccgcggcg gagggtgggc gcgcggggag      120

cgggatggag ccggggctgt gaggccgagg cggcggtgcc tgggaggaag ggtcggatgc      180

cggaccgggg gcaccgctga ggcggtgggt ccccgacctg cgagacaggt ttggaagccc      240

ccgctgcgcc cagtccgtgc ggaccgcgag gccgcgggcg ggtggaggcg cgtctccggc      300

acgatgaagg atttgggggc agagcacttg gcaggtcatg aaggggtcca acttctcggg      360

ttgttgaacg tctacctgga acaagaagag agattccaac ctcgagaaaa agggctgagt      420

ttgattgagg ctaccccgga gaatgataac actttgtgtc caggattgag aaatgccaaa      480

gttgaagatt taaggagttt agccaacttt tttggatctt gcactgaaac ttttgtcctg      540

gctgtcaata ttttggacag gttcttggct cttatgaagg tgaaacctaa acatttgtct      600

tgcattggag tctgttcttt tttgctggct gctagaatag ttgaagaaga ctgcaatatt      660

ccatccactc atgatgtgat ccggattagt cagtgtaaat gtactgcttc tgacataaaa      720

cggatggaaa aaataatttc agaaaaattg cactatgaat tggaagctac tactgcctta      780

aactttttgc acttatacca tactattata ctttgtcata cttcagaaag gaaagaaata      840

ctgagccttg ataaactaga agctcagctg aaagcttgca actgccgact catcttttca      900

aaagcaaaac catctgtatt agccttgtgc cttctcaatt tggaagtgga aactttgaaa      960

tctgttgaat tactggaaat tctcttgcta gttaaaaaac attccaagat taatgacact     1020

gagttcttct actggagaga gttggtttct aaatgcctag ccgagtattc ttctcctgaa     1080

tgttgcaaac cagatcttaa gaagttggtt tggatcgttt caaggcgcac agcccagaac     1140

ctccacaaca gctactatag tgttcctgag ctgccaacga tacctgaggg gggttgtttt     1200

gatgaaagtg aaagtgagga ctcttgtgaa gatatgagtt gtggagagga gagtctcagc     1260

agctctcctc ccagtgatca agagtgcacc ttctttttca acttcaaagt ggcacaaaca     1320

ctgtgctttc catcttagaa atctgattgt tctgtcagaa tttatattta caggtttcaa     1380

agcaataaat gggggaatag gtagtttcct ggtttagccc ccatctagtc aggaattaat     1440

atactggaat acctaccttc tatttgttat tcagatcaga tctggcctat tttcatattt     1500

atcctaagcc atcaaatggg gtagtgcctc ttaaaccatt aacagtactt tagacattgg     1560

cactttattt ttctcgtaga tctttagcta ctttggggag gagggaaggt gctgatacct     1620

tcaatttgtt acttttcaag atttttaaaa ataactagtg tagcttatct taaacatttt     1680

ataaaacctt cagatgtctt taagcagatt ggaagtatgc aagtgcttcc ttagcaggga     1740

cagtggataa tccttaatgg tttatcatag atttcaccct ccccccttct cagaagagtg     1800

agtatgctct taaatgtcaa acacattttt gttgttttgt tttttaaatg atcagtgtct     1860

atttgatgtg atgcagatct tataaatttg ggaattataa tattgacatt tctgtgattt     1920

ttatatatgt aatgtcttaa ttgagatttc tgttaaggca gaaataatta ggctagggct     1980

cttagttttc attcctattg cccaagtatt gtcaaactat ggtattattt taatgttact     2040

ttaaaaatcc ataatctgct agttttgcat gtacttatat gaaaacagtg cagtaagttg     2100

aaaactcagt atctatggaa ttgataaatg ttgatctggt gtagtatatt ttatcgcatt     2160

ttcttatatt aaaaaatgtc tgcatgatta cattttattt cctttgtaat ttacatttca     2220

gaatagtgta ttgctatatg ggtgccaaga ttgaatatga agaacccgag tgtttgtagt     2280

attatagttt taagcaaatc tgtgtggtga tacagccata agaatggggc ttatataaac     2340

tctgtacatg taagattttg tacagagaat ttttaacttt ataaattgta tatgaacatg     2400

taaatctttt aaaatgtaca taaaatactg tattttttta ccttgtgtgt gatagtctag     2460

tcattgcatg taaatataat ttattatgta ttctgtagta taaatcatac attgatgact     2520

tacattttta ctggtaagtc aacatccgtt ggatgttttc tgaagtggct ctttttgaag     2580

tgataataga ttgtaattca aaataaaatt attaatgaat tctccttgtt tgggatcaca     2640

tcttaatttt taatctgtta aaagttcttg atgtatttta atgagaagac tttaggtgag     2700

gctacagtga ttccagagtg agccttctaa ctggctagca gaagttctct aggtttggca     2760

tctgtgcctt ggagatactg aaagagaatc tgtcatttga caattgacct ctttgtggga     2820

tggactcatt aagtatgctc tcagagactg gtatattacc agaatgccta ttaattttca     2880

gtgagaggca acaggtatta agtagaacag aatgctcagg ttggcagatt agaacgatct     2940

ttcaggagac aaagcaagtt ttaatcagtt gtttggttaa taagtatggg gtgttcgctg     3000

tgatagggcc ccgccagctt ctggctcttg tggacctcaa aagtatcagg tggttttgca     3060

agtggtggtc ctttcccctg ccccacccca ataggttccc catctgtcta gtttgatttt     3120

tgtagacctt tgttttctct agttagaaaa tcaggtacac tgaatatggt tttcatgtaa     3180

cacctcttct ctggagatag gggtatgttt tcctaccctt ctagtggaga atcctacttg     3240

aggatgacct ttcctctctt actaaataat attagtaaat agtgggcaat atattctgct     3300

ttcagatttt gatttgttga gatgtaaaag ttgtttgggg cttaccaaat ctcaagactc     3360

tctttagctc ctgcaggatt gtattgcttt tcttactgga tatttttcct gggtaagcat     3420

ctttgtggct tcatctcttc cccctgtggt tttcagtgta tttagtcgag acctctctgc     3480

tgagcttgca acctgtttat tcacatggcc tgccatgcca cttggaggtt tctgattact     3540

cccaaacctg ctggttcttt atgtctttct cagcgaataa ttccatctat tcatgttgga     3600

aacttaggtg atatgctcat ctccttttgc ctgtttatgg aggtcaccag cctctatcat     3660

ttgtatgatt tcgtttacac tgtttatatc tctctgtccc ccctttttct gccattggca     3720

tggtttagac ctgtactctt tatcagcaga ggtactgtaa tatatttgtg atccctcagc     3780

ttccaggctt actcctggtc tctgccttcc tatctacata tccttttaaa ataaaatttt     3840

aactatctcc tgaaaaattg ttgagtaggt cacgcacaat caggagaaaa atctattcat     3900

gacatacaag tctctgtcta atctgaacac tgcacctgtc tctggccttt ttttcttgtc     3960

atttcctaga ccttaaaaaa tgtgtattga gaaagaactc tgttagctat acagaagatg     4020

aactgggcaa tatagagtag cagcatggag accagtctga ctgaactaag gcagtggaag     4080

tgtggatgag gaagagaggt gaaaattgag aagcgctatc ctttctcttt gggcattatt     4140

aggaggctca cagacaagtc caggagcctg gttataccct cctgtgccat tcaaccaggt     4200

ggctttccca tgactgtgat gaataaaatt gagaagcccc tgcccttttc agagcagagg     4260

gtgaggagaa agctaccatt ttgtcctcat ccttaccccc gttgacttgg cgagagattt     4320

gacctttcag gttttgatcc tgtcattttc taggatgtgg tgcacgcact ttgctgttgc     4380

gcatggtgaa gtattgtgcc taggtcctgg gtcttcatct gtttggctct gctactgttt     4440

cctcctccca ggaagtgtgg ttagacaaat aatgtgtttt aattacctgt cacactcagg     4500

attaatacat actcaggtta actgtagaga ggcattggct tcagaacact cctcgtgaca     4560

attttaacca ttttctttgt ctagagtctg cctttttctt ttttacaatt tcttttattt     4620

caacactagg tttcaatatg gtgttcctgc tacctcccac ctccctcctc cctcatcaca     4680

catgcaaatt gtcagcttat tgagacaacc cacttagatt catatatgga caaggacaag     4740

gtattttgca tttgttactg gaattcagtt ttcctaacta tttactacca gaaatggtca     4800

ataacttact ttgtgtttag caaatcaaat tgtgtgatag atagtttccc agtatgatgg     4860

ccagtcagtc tttccatccc tgtgcctaca tgctgctctt cccgtccaca agtggagtct     4920

gtttctcttg agttttggct ggccttatga atggctttgc ttactgaagt gcagcagaag     4980

aaatttagta tatgtccaag cctaggcttt aagagactgg cagctttcct tttatccttt     5040

ttggaagcta gccaccatgc tgcaaagaag ctcagctgga ttactgaaag atgagaggcc     5100

atgtggagag agactcttga ggatgagaga ttatcttgga tgttccagcc ttaagctccc     5160

agctgaatgt gggtgtatcc tcagctacac cacagaaaac agaggaacta ctcagtcgat     5220

cccaatcaac ccacagactc actagaaata acaaattatt gttttaagcc acgaggtttt     5280

gggggagggt tgttaaacag taatagataa gtgagacaga ttgcttgtta tttatggtca     5340

aatggtgatt atctctggtg agattacagg tgatgttttt tttaagttat gcctatctgt     5400

agtttccttt ttttcctaaa attgatttga attattagtg tattaacaga ataaagaatg     5460

aactttaaaa cacaaaaaaa aaaaaaaaa                                       5489


<210>  1443
<211>  4120
<212>  DNA
<213>  homo sapiens

<400>  1443
atgctgaccg tacccaggcg ggagccgccg cgccgccgcc tggcgctgca cctgggcccg       60

gcccggccgc caattggacg gctcggggcg accccgctgt atcgcgagac gagattggca      120

gcggcggggc ctcaagtgcc cccgcgctgg ctttgtatgc ggagccgcct gccggtcctt      180

taacaatggg cggcgcgagc gtccaggcgc tgggctctag ctgaggccgg cgcttagcgg      240

cccactgtcc gcagcatgag cggggccggc gtccgccgca cgacggcggg gctggggctg      300

tgagggccgc ggttccggac tcgagttgcc gcgtcgggct gggcgcgccg ccgggtccca      360

tggagctgga ggggcagtgg tggcgaggac agctggccgc cgatattcac caagcgcttc      420

gctacaagga gctgaagttg ccctcctata aaggccagtc ccctcagtta agtctcagac      480

ggtattttgc tgacttgatt gccattgtga gcaatcgctt cacactctgc ccttctgccc      540

gccatcttgc tgtctattta ctggacctgt ttatggaccg ctatgacatc tctatccagc      600

agctgcattt agttgcgctt tcctgcctgc ttctagcaag taaatttgaa gaaaaagaag      660

acagtgtgcc taagctggag cagctcaaca gcctgggttg tatgactaat atgaatctag      720

tattaacaaa acaaaatttg ctacatatgg aactattatt attagaaacc tttcagtgga      780

acctctgcct tccaacagcc gcccatttca ttgagtatta tctctctgaa gcagtacacg      840

aaacagatct tcatgacggc tggccaatga tttgcttgga aaagactaaa ctctacatgg      900

ccaaatatgc agattacttc ctggaagtat ctttgcaagt agctgctgca tgtgtggctt      960

cttcgaggat tatacttcgt ctttctccaa cgtggcctac aagactacat cgtcttactg     1020

cctactcttg ggatttctta gtgcagtgta ttgaacgact gttgatcgct catgataatg     1080

atgtgaaaga agcaaacaaa cagagagggc aagcaggacc tcagtcagcg caactaagtg     1140

tattccagac agcctcccag ccatcacggc cagttcactt tcagcaacct cagtatctcc     1200

atcagacaca tcagacctca ctgcagtatc gccatcctac gtcagaacaa ccaagctgtc     1260

agcagattgt atcgaccaca cacacctcat cttacacact acagacatgt cctgctggct     1320

tccaaactag tgttcagggc cttgggcaca tgcagactgg tgttgggatg tcactggcaa     1380

taccagtaga agttaagccc tgtctgagtg tttcttacaa ccggagttat cagataaatg     1440

aacattaccc ttgtattact ccatgttttg aaaggtgatt atttgtgaag ctgataaccg     1500

acccagactg ctttgtgaca tgaagctatg ggtaagcgtt ttgtaaactt ctgttcaaaa     1560

ggaaagggat ctaaatgaca tcagaactct tcaggtacca gcaccaggaa gactgaatat     1620

cctttttaat gcaccatgaa tcctgggaga ctaagcaaat taacagtatg tcaaattctg     1680

ttacaacaaa tccctgtatg acaaaaatgt tcaagtcctg gctgatggtc caaatatttc     1740

aaaaatattc agtacaacag aaaatttgga cagacttcaa tttgccattt tgagatttga     1800

cctgtggtag catctgggcc taatgttggc ttctaagtca aagactaaat gtttatctca     1860

tctatggact tgccaaacag tcttttatga aggaaagtta cagtattaat ttttgaaaag     1920

gtttttttta ttctgcaatt ttttattttt gttctacaca tgaatttttg actaagttta     1980

aactcatgaa ttgttatgct ataccaatct gcagtaaaaa aaattttttt agatgattct     2040

atataacttc gtctcacaaa tagtgtaggt atctgggttt atatactaaa attaagggtg     2100

gagaagatct tattttttaa atcatggtca taatttttct ttttttccct aagtgatcaa     2160

catcaaattt ttagaattaa aatacattta actcagggaa tttgtactac ttggaaacac     2220

ttaactgtaa tgcaacatgc cttgggaatg ttatagtgtg aactaccttt ataacatagg     2280

ttaaaatacg cttgctaggg tgtgttttca aatgagaaca taatatagct cagaatgaag     2340

tggtagttcc tgtgattcat aatacatatg taggttttgc atatctcagt gcaatccatg     2400

atttatactc agaatcgaca ttcttaaaaa gttatttcaa gggatggcat aactgtaaga     2460

ggtcagtgct agaataaagt cctgtaggtt tattttggaa gggactgtgg ccagggtagt     2520

tctcaggttg tgctagagca gcactttgtt atgtggaaga caggtttttt aagcaacctt     2580

tgaatccagc tctagtcagt ctaagcaggc aaaggtaact gatgactaaa tttcagtagc     2640

tactttcatt ggattgaccc tacaactgcc ctgggacatt tcactgtacc agtattaact     2700

gcaaacagca ataattgtca ttacagcaag ggcagtttgg gggtaaagca ttttggagga     2760

ataaccttaa aaagttaaaa agtcattgta ataactgata aactgtatac attgtgctcc     2820

tttctgtggg agaagaaaga tttggtggag ggaagctttc tggtttaaaa attagtaagg     2880

tgtgtctttt tgtttttttt aagatagcac ttgaatagaa gggaaaactg catggcagat     2940

acgtgactgc cacaatatgc atcgaagaca aacttactat aaagatgttg tgggtatgca     3000

gcaggagtct cagtaatcaa gccaatggcc tttgtcagga agggaagggg ctcaacacag     3060

tgatggactg atccagatgg ctcccgggga tgaatgtggg tgggtagctt ctgtcagtat     3120

caatgcttag agaaatatcc tttccttaaa aagaaaataa cttttatatt tagagtacat     3180

agggcatgat gtggatttat tagtctggta gataaaatga aaaaccactc aggtaagaac     3240

actcactcat ggcagttttt aagcatgaaa attgttttct gaaagtatca tcacttttcc     3300

tttttaaaga aggctgctaa ttggattttg gtagttctta cctcaagaaa acttgaatta     3360

tttgggggaa agtaggctca aaagagaata tatctttcac attcacattc agaacccagc     3420

aacctggagt ccaattttca gtattttaac tacctcaata atgctatgaa tgtaagatat     3480

tgggatagag atcccaactt gaaacaacag ccagtgcctg tggtaactta atgtcttgtc     3540

aaatactttt attgattggt ttatatgcca ttcttgttat agaagaatat gccttttaaa     3600

aaagcttatt aataacactt tcccaattta tattttaaaa agctaaagaa cactggatta     3660

ataatctttt gggagggtag aataaaataa ttgattacta ttgctgcata cccggggtgg     3720

gatggggtgg ttggagaacc agaactattt ttaaaacatt aggtttcaat ataaatacaa     3780

ctcacaactg ctagctttgg ggggtggggg aacattgtgt gggttttgtt ttgtttaatt     3840

tattgattag tctttaaagt aggctttttt tttttttttt gagaatactg gaccatcatt     3900

aaatgtgtac tgtgaagaga ttaatatgta tgaagggctt taccaaagtc cactaaataa     3960

acactactca agtacagact gcaaaccaaa atgtatctgt gttacgacat taattgcaaa     4020

tagcaagtat ggtgctaaag tctacaccaa tggaattaga tgagtgctat gcacttaatt     4080

ttaaaataaa actagttttc agtaaaaaaa aaaaaaaaaa                           4120


<210>  1444
<211>  4153
<212>  DNA
<213>  homo sapiens

<400>  1444
atgctgaccg tacccaggcg ggagccgccg cgccgccgcc tggcgctgca cctgggcccg       60

gcccggccgc caattggacg gctcggggcg accccgctgt atcgcgagac gagattggca      120

gcggcggggc ctcaagtgcc cccgcgctgg ctttgtatgc ggagccgcct gccggtcctt      180

taacaatggg cggcgcgagc gtccaggcgc tgggctctag ctgaggccgg cgcttagcgg      240

cccactgtcc gcagcatgag cggggccggc gtccgccgca cgacggcggg gctggggctg      300

tgagggccgc ggttccggac tcgagttgcc gcgtcgggct gggcgcgccg ccgggtccca      360

tggagctgga ggggcagtgg tggcgaggac agctggccgc cgatattcac caagcgcttc      420

gctacaagga gctgaagttg ccctcctata aaggccagtc ccctcagtta agtctcagac      480

ggtattttgc tgacttgatt gccattgtga gcaatcgctt cacactctgc ccttctgccc      540

gccatcttgc tgtctattta ctggacctgt ttatggaccg ctatgacatc tctatccagc      600

agctgcattt agttgcgctt tcctgcctgc ttctagcaag taaatttgaa gaaaaagaag      660

acagtgtgcc taagctggag cagctcaaca gcctgggttg tatgactaat atgaatctag      720

tattaacaaa acaaaatttg ctacatatgg aactattatt attagaaacc tttcagtgga      780

acctctgcct tccaacagcc gcccatttca ttgagtatta tctctctgaa gcagtacacg      840

aaacagatct tcatgacggc tggccaatga tttgcttgga aaagactaaa ctctacatgg      900

ccaaatatgc agattacttc ctggaagtat ctttgcaaga ttatgccttt ctaaattatg      960

caccttcttt agtagctgct gcatgtgtgg cttcttcgag gattatactt cgtctttctc     1020

caacgtggcc tacaagacta catcgtctta ctgcctactc ttgggatttc ttagtgcagt     1080

gtattgaacg actgttgatc gctcatgata atgatgtgaa agaagcaaac aaacagagag     1140

ggcaagcagg acctcagtca gcgcaactaa gtgtattcca gacagcctcc cagccatcac     1200

ggccagttca ctttcagcaa cctcagtatc tccatcagac acatcagacc tcactgcagt     1260

atcgccatcc tacgtcagaa caaccaagct gtcagcagat tgtatcgacc acacacacct     1320

catcttacac actacagaca tgtcctgctg gcttccaaac tagtgttcag ggccttgggc     1380

acatgcagac tggtgttggg atgtcactgg caataccagt agaagttaag ccctgtctga     1440

gtgtttctta caaccggagt tatcagataa atgaacatta cccttgtatt actccatgtt     1500

ttgaaaggtg attatttgtg aagctgataa ccgacccaga ctgctttgtg acatgaagct     1560

atgggtaagc gttttgtaaa cttctgttca aaaggaaagg gatctaaatg acatcagaac     1620

tcttcaggta ccagcaccag gaagactgaa tatccttttt aatgcaccat gaatcctggg     1680

agactaagca aattaacagt atgtcaaatt ctgttacaac aaatccctgt atgacaaaaa     1740

tgttcaagtc ctggctgatg gtccaaatat ttcaaaaata ttcagtacaa cagaaaattt     1800

ggacagactt caatttgcca ttttgagatt tgacctgtgg tagcatctgg gcctaatgtt     1860

ggcttctaag tcaaagacta aatgtttatc tcatctatgg acttgccaaa cagtctttta     1920

tgaaggaaag ttacagtatt aatttttgaa aaggtttttt ttattctgca attttttatt     1980

tttgttctac acatgaattt ttgactaagt ttaaactcat gaattgttat gctataccaa     2040

tctgcagtaa aaaaaatttt tttagatgat tctatataac ttcgtctcac aaatagtgta     2100

ggtatctggg tttatatact aaaattaagg gtggagaaga tcttattttt taaatcatgg     2160

tcataatttt tctttttttc cctaagtgat caacatcaaa tttttagaat taaaatacat     2220

ttaactcagg gaatttgtac tacttggaaa cacttaactg taatgcaaca tgccttggga     2280

atgttatagt gtgaactacc tttataacat aggttaaaat acgcttgcta gggtgtgttt     2340

tcaaatgaga acataatata gctcagaatg aagtggtagt tcctgtgatt cataatacat     2400

atgtaggttt tgcatatctc agtgcaatcc atgatttata ctcagaatcg acattcttaa     2460

aaagttattt caagggatgg cataactgta agaggtcagt gctagaataa agtcctgtag     2520

gtttattttg gaagggactg tggccagggt agttctcagg ttgtgctaga gcagcacttt     2580

gttatgtgga agacaggttt tttaagcaac ctttgaatcc agctctagtc agtctaagca     2640

ggcaaaggta actgatgact aaatttcagt agctactttc attggattga ccctacaact     2700

gccctgggac atttcactgt accagtatta actgcaaaca gcaataattg tcattacagc     2760

aagggcagtt tgggggtaaa gcattttgga ggaataacct taaaaagtta aaaagtcatt     2820

gtaataactg ataaactgta tacattgtgc tcctttctgt gggagaagaa agatttggtg     2880

gagggaagct ttctggttta aaaattagta aggtgtgtct ttttgttttt tttaagatag     2940

cacttgaata gaagggaaaa ctgcatggca gatacgtgac tgccacaata tgcatcgaag     3000

acaaacttac tataaagatg ttgtgggtat gcagcaggag tctcagtaat caagccaatg     3060

gcctttgtca ggaagggaag gggctcaaca cagtgatgga ctgatccaga tggctcccgg     3120

ggatgaatgt gggtgggtag cttctgtcag tatcaatgct tagagaaata tcctttcctt     3180

aaaaagaaaa taacttttat atttagagta catagggcat gatgtggatt tattagtctg     3240

gtagataaaa tgaaaaacca ctcaggtaag aacactcact catggcagtt tttaagcatg     3300

aaaattgttt tctgaaagta tcatcacttt tcctttttaa agaaggctgc taattggatt     3360

ttggtagttc ttacctcaag aaaacttgaa ttatttgggg gaaagtaggc tcaaaagaga     3420

atatatcttt cacattcaca ttcagaaccc agcaacctgg agtccaattt tcagtatttt     3480

aactacctca ataatgctat gaatgtaaga tattgggata gagatcccaa cttgaaacaa     3540

cagccagtgc ctgtggtaac ttaatgtctt gtcaaatact tttattgatt ggtttatatg     3600

ccattcttgt tatagaagaa tatgcctttt aaaaaagctt attaataaca ctttcccaat     3660

ttatatttta aaaagctaaa gaacactgga ttaataatct tttgggaggg tagaataaaa     3720

taattgatta ctattgctgc atacccgggg tgggatgggg tggttggaga accagaacta     3780

tttttaaaac attaggtttc aatataaata caactcacaa ctgctagctt tggggggtgg     3840

gggaacattg tgtgggtttt gttttgttta atttattgat tagtctttaa agtaggcttt     3900

tttttttttt tttgagaata ctggaccatc attaaatgtg tactgtgaag agattaatat     3960

gtatgaaggg ctttaccaaa gtccactaaa taaacactac tcaagtacag actgcaaacc     4020

aaaatgtatc tgtgttacga cattaattgc aaatagcaag tatggtgcta aagtctacac     4080

caatggaatt agatgagtgc tatgcactta attttaaaat aaaactagtt ttcagtaaaa     4140

aaaaaaaaaa aaa                                                        4153


<210>  1445
<211>  4117
<212>  DNA
<213>  homo sapiens

<400>  1445
atgctgaccg tacccaggcg ggagccgccg cgccgccgcc tggcgctgca cctgggcccg       60

gcccggccgc caattggacg gctcggggcg accccgctgt atcgcgagac gagattggca      120

gcggcggggc ctcaagtgcc cccgcgctgg ctttgtatgc ggagccgcct gccggtcctt      180

taacaatggg cggcgcgagc gtccaggcgc tgggctctag ctgaggccgg cgcttagcgg      240

cccactgtcc gcagcatgag cggggccggc gtccgccgca cgacggcggg gctggggctg      300

tgagggccgc ggttccggac tcgagttgcc gcgtcgggct gggcgcgccg ccgggtccca      360

tggagctgga ggggcagtgg tggcgaggac agctggccgc cgatattcac caagcgcttc      420

gctacaagga gctgaagttg ccctcctata aaggccagtc ccctcagtta agtctcagac      480

ggtattttgc tgacttgatt gccattgtga gcaatcgctt cacactctgc ccttctgccc      540

gccatcttgc tgtctattta ctggacctgt ttatggaccg ctatgacatc tctatccagc      600

agctgcattt agttgcgctt tcctgcctgc ttctagcaag taaatttgaa gaaaaagaag      660

acagtgtgcc taagctggag cagctcaaca gcctgggttg tatgactaat atgaatctag      720

tattaacaaa acaaaatttg ctacatatgg aactattatt attagaaacc tttcagtgga      780

acctctgcct tccaacagcc gcccatttca ttgagtatta tctctctgaa gcagtacacg      840

aaacagatct tcatgacggc tggccaatga tttgcttgga aaagactaaa ctctacatgg      900

ccaaatatgc agattacttc ctggaagtat ctttgcaagc tgctgcatgt gtggcttctt      960

cgaggattat acttcgtctt tctccaacgt ggcctacaag actacatcgt cttactgcct     1020

actcttggga tttcttagtg cagtgtattg aacgactgtt gatcgctcat gataatgatg     1080

tgaaagaagc aaacaaacag agagggcaag caggacctca gtcagcgcaa ctaagtgtat     1140

tccagacagc ctcccagcca tcacggccag ttcactttca gcaacctcag tatctccatc     1200

agacacatca gacctcactg cagtatcgcc atcctacgtc agaacaacca agctgtcagc     1260

agattgtatc gaccacacac acctcatctt acacactaca gacatgtcct gctggcttcc     1320

aaactagtgt tcagggcctt gggcacatgc agactggtgt tgggatgtca ctggcaatac     1380

cagtagaagt taagccctgt ctgagtgttt cttacaaccg gagttatcag ataaatgaac     1440

attacccttg tattactcca tgttttgaaa ggtgattatt tgtgaagctg ataaccgacc     1500

cagactgctt tgtgacatga agctatgggt aagcgttttg taaacttctg ttcaaaagga     1560

aagggatcta aatgacatca gaactcttca ggtaccagca ccaggaagac tgaatatcct     1620

ttttaatgca ccatgaatcc tgggagacta agcaaattaa cagtatgtca aattctgtta     1680

caacaaatcc ctgtatgaca aaaatgttca agtcctggct gatggtccaa atatttcaaa     1740

aatattcagt acaacagaaa atttggacag acttcaattt gccattttga gatttgacct     1800

gtggtagcat ctgggcctaa tgttggcttc taagtcaaag actaaatgtt tatctcatct     1860

atggacttgc caaacagtct tttatgaagg aaagttacag tattaatttt tgaaaaggtt     1920

ttttttattc tgcaattttt tatttttgtt ctacacatga atttttgact aagtttaaac     1980

tcatgaattg ttatgctata ccaatctgca gtaaaaaaaa tttttttaga tgattctata     2040

taacttcgtc tcacaaatag tgtaggtatc tgggtttata tactaaaatt aagggtggag     2100

aagatcttat tttttaaatc atggtcataa tttttctttt tttccctaag tgatcaacat     2160

caaattttta gaattaaaat acatttaact cagggaattt gtactacttg gaaacactta     2220

actgtaatgc aacatgcctt gggaatgtta tagtgtgaac tacctttata acataggtta     2280

aaatacgctt gctagggtgt gttttcaaat gagaacataa tatagctcag aatgaagtgg     2340

tagttcctgt gattcataat acatatgtag gttttgcata tctcagtgca atccatgatt     2400

tatactcaga atcgacattc ttaaaaagtt atttcaaggg atggcataac tgtaagaggt     2460

cagtgctaga ataaagtcct gtaggtttat tttggaaggg actgtggcca gggtagttct     2520

caggttgtgc tagagcagca ctttgttatg tggaagacag gttttttaag caacctttga     2580

atccagctct agtcagtcta agcaggcaaa ggtaactgat gactaaattt cagtagctac     2640

tttcattgga ttgaccctac aactgccctg ggacatttca ctgtaccagt attaactgca     2700

aacagcaata attgtcatta cagcaagggc agtttggggg taaagcattt tggaggaata     2760

accttaaaaa gttaaaaagt cattgtaata actgataaac tgtatacatt gtgctccttt     2820

ctgtgggaga agaaagattt ggtggaggga agctttctgg tttaaaaatt agtaaggtgt     2880

gtctttttgt tttttttaag atagcacttg aatagaaggg aaaactgcat ggcagatacg     2940

tgactgccac aatatgcatc gaagacaaac ttactataaa gatgttgtgg gtatgcagca     3000

ggagtctcag taatcaagcc aatggccttt gtcaggaagg gaaggggctc aacacagtga     3060

tggactgatc cagatggctc ccggggatga atgtgggtgg gtagcttctg tcagtatcaa     3120

tgcttagaga aatatccttt ccttaaaaag aaaataactt ttatatttag agtacatagg     3180

gcatgatgtg gatttattag tctggtagat aaaatgaaaa accactcagg taagaacact     3240

cactcatggc agtttttaag catgaaaatt gttttctgaa agtatcatca cttttccttt     3300

ttaaagaagg ctgctaattg gattttggta gttcttacct caagaaaact tgaattattt     3360

gggggaaagt aggctcaaaa gagaatatat ctttcacatt cacattcaga acccagcaac     3420

ctggagtcca attttcagta ttttaactac ctcaataatg ctatgaatgt aagatattgg     3480

gatagagatc ccaacttgaa acaacagcca gtgcctgtgg taacttaatg tcttgtcaaa     3540

tacttttatt gattggttta tatgccattc ttgttataga agaatatgcc ttttaaaaaa     3600

gcttattaat aacactttcc caatttatat tttaaaaagc taaagaacac tggattaata     3660

atcttttggg agggtagaat aaaataattg attactattg ctgcataccc ggggtgggat     3720

ggggtggttg gagaaccaga actattttta aaacattagg tttcaatata aatacaactc     3780

acaactgcta gctttggggg gtgggggaac attgtgtggg ttttgttttg tttaatttat     3840

tgattagtct ttaaagtagg cttttttttt tttttttgag aatactggac catcattaaa     3900

tgtgtactgt gaagagatta atatgtatga agggctttac caaagtccac taaataaaca     3960

ctactcaagt acagactgca aaccaaaatg tatctgtgtt acgacattaa ttgcaaatag     4020

caagtatggt gctaaagtct acaccaatgg aattagatga gtgctatgca cttaatttta     4080

aaataaaact agttttcagt aaaaaaaaaa aaaaaaa                              4117


<210>  1446
<211>  4120
<212>  DNA
<213>  homo sapiens

<400>  1446
atgctgaccg tacccaggcg ggagccgccg cgccgccgcc tggcgctgca cctgggcccg       60

gcccggccgc caattggacg gctcggggcg accccgctgt atcgcgagac gagattggca      120

gcggcggggc ctcaagtgcc cccgcgctgg ctttgtatgc ggagccgcct gccggtcctt      180

taacaatggg cggcgcgagc gtccaggcgc tgggctctag ctgaggccgg cgcttagcgg      240

cccactgtcc gcagcatgag cggggccggc gtccgccgca cgacggcggg gctggggctg      300

tgagggccgc ggttccggac tcgagttgcc gcgtcgggct gggcgcgccg ccgggtccca      360

tggagctgga ggggcagtgg tggcgaggac agctggccgc cgatattcac caagcgcttc      420

gctacaagga gctgaagttg ccctcctata aaggccagtc ccctcagtta agtctcagac      480

ggtattttgc tgacttgatt gccattgtga gcaatcgctt cacactctgc ccttctgccc      540

gccatcttgc tgtctattta ctggacctgt ttatggaccg ctatgacatc tctatccagc      600

agctgcattt agttgcgctt tcctgcctgc ttctagcaag taaatttgaa gaaaaagaag      660

acagtgtgcc taagctggag cagctcaaca gcctgggttg tatgactaat atgaatctag      720

tattaacaaa acaaaatttg ctacatatgg aactattatt attagaaacc tttcagtgga      780

acctctgcct tccaacagcc gcccatttca ttgagtatta tctctctgaa gcagtacacg      840

aaacagatct tcatgacggc tggccaatga tttgcttgga aaagactaaa ctctacatgg      900

ccaaatatgc agattacttc ctggaagtat ctttgcaagt agctgctgca tgtgtggctt      960

cttcgaggat tatacttcgt ctttctccaa cgtggcctac aagactacat cgtcttactg     1020

cctactcttg ggatttctta gtgcagtgta ttgaacgact gttgatcgct catgataatg     1080

atgtgaaaga agcaaacaaa cagagagggc aagcaggacc tcagtcagcg caactaagtg     1140

tattccagac agcctcccag ccatcacggc cagttcactt tcagcaacct cagtatctcc     1200

atcagacaca tcagacctca ctgcagtatc gccatcctac gtcagaacaa ccaagctgtc     1260

agcagattgt atcgaccaca cacacctcat cttacacact acagacatgt cctgctggct     1320

tccaaactag tgttcagggc cttgggcaca tgcagactgg tgttgggatg tcactggcaa     1380

taccagtaga agttaagccc tgtctgagtg tttcttacaa ccggagttat cagataaatg     1440

aacattaccc ttgtattact ccatgttttg aaaggtgatt atttgtgaag ctgataaccg     1500

acccagactg ctttgtgaca tgaagctatg ggtaagcgtt ttgtaaactt ctgttcaaaa     1560

ggaaagggat ctaaatgaca tcagaactct tcaggtacca gcaccaggaa gactgaatat     1620

cctttttaat gcaccatgaa tcctgggaga ctaagcaaat taacagtatg tcaaattctg     1680

ttacaacaaa tccctgtatg acaaaaatgt tcaagtcctg gctgatggtc caaatatttc     1740

aaaaatattc agtacaacag aaaatttgga cagacttcaa tttgccattt tgagatttga     1800

cctgtggtag catctgggcc taatgttggc ttctaagtca aagactaaat gtttatctca     1860

tctatggact tgccaaacag tcttttatga aggaaagtta cagtattaat ttttgaaaag     1920

gtttttttta ttctgcaatt ttttattttt gttctacaca tgaatttttg actaagttta     1980

aactcatgaa ttgttatgct ataccaatct gcagtaaaaa aaattttttt agatgattct     2040

atataacttc gtctcacaaa tagtgtaggt atctgggttt atatactaaa attaagggtg     2100

gagaagatct tattttttaa atcatggtca taatttttct ttttttccct aagtgatcaa     2160

catcaaattt ttagaattaa aatacattta actcagggaa tttgtactac ttggaaacac     2220

ttaactgtaa tgcaacatgc cttgggaatg ttatagtgtg aactaccttt ataacatagg     2280

ttaaaatacg cttgctaggg tgtgttttca aatgagaaca taatatagct cagaatgaag     2340

tggtagttcc tgtgattcat aatacatatg taggttttgc atatctcagt gcaatccatg     2400

atttatactc agaatcgaca ttcttaaaaa gttatttcaa gggatggcat aactgtaaga     2460

ggtcagtgct agaataaagt cctgtaggtt tattttggaa gggactgtgg ccagggtagt     2520

tctcaggttg tgctagagca gcactttgtt atgtggaaga caggtttttt aagcaacctt     2580

tgaatccagc tctagtcagt ctaagcaggc aaaggtaact gatgactaaa tttcagtagc     2640

tactttcatt ggattgaccc tacaactgcc ctgggacatt tcactgtacc agtattaact     2700

gcaaacagca ataattgtca ttacagcaag ggcagtttgg gggtaaagca ttttggagga     2760

ataaccttaa aaagttaaaa agtcattgta ataactgata aactgtatac attgtgctcc     2820

tttctgtggg agaagaaaga tttggtggag ggaagctttc tggtttaaaa attagtaagg     2880

tgtgtctttt tgtttttttt aagatagcac ttgaatagaa gggaaaactg catggcagat     2940

acgtgactgc cacaatatgc atcgaagaca aacttactat aaagatgttg tgggtatgca     3000

gcaggagtct cagtaatcaa gccaatggcc tttgtcagga agggaagggg ctcaacacag     3060

tgatggactg atccagatgg ctcccgggga tgaatgtggg tgggtagctt ctgtcagtat     3120

caatgcttag agaaatatcc tttccttaaa aagaaaataa cttttatatt tagagtacat     3180

agggcatgat gtggatttat tagtctggta gataaaatga aaaaccactc aggtaagaac     3240

actcactcat ggcagttttt aagcatgaaa attgttttct gaaagtatca tcacttttcc     3300

tttttaaaga aggctgctaa ttggattttg gtagttctta cctcaagaaa acttgaatta     3360

tttgggggaa agtaggctca aaagagaata tatctttcac attcacattc agaacccagc     3420

aacctggagt ccaattttca gtattttaac tacctcaata atgctatgaa tgtaagatat     3480

tgggatagag atcccaactt gaaacaacag ccagtgcctg tggtaactta atgtcttgtc     3540

aaatactttt attgattggt ttatatgcca ttcttgttat agaagaatat gccttttaaa     3600

aaagcttatt aataacactt tcccaattta tattttaaaa agctaaagaa cactggatta     3660

ataatctttt gggagggtag aataaaataa ttgattacta ttgctgcata cccggggtgg     3720

gatggggtgg ttggagaacc agaactattt ttaaaacatt aggtttcaat ataaatacaa     3780

ctcacaactg ctagctttgg ggggtggggg aacattgtgt gggttttgtt ttgtttaatt     3840

tattgattag tctttaaagt aggctttttt tttttttttt gagaatactg gaccatcatt     3900

aaatgtgtac tgtgaagaga ttaatatgta tgaagggctt taccaaagtc cactaaataa     3960

acactactca agtacagact gcaaaccaaa atgtatctgt gttacgacat taattgcaaa     4020

tagcaagtat ggtgctaaag tctacaccaa tggaattaga tgagtgctat gcacttaatt     4080

ttaaaataaa actagttttc agtaaaaaaa aaaaaaaaaa                           4120


<210>  1447
<211>  2301
<212>  DNA
<213>  homo sapiens

<400>  1447
aaacggagtg ggagaagggg gctagcgagg aggaagaggc gggaggtgcg gcaggggcac       60

aggtgacgct cctcccgcct gcctagcaga gctccaggcg cacatccgca gtcagccacc      120

tcgcgcgcgc ctccaggagc aaggatggag aggctgactc tgaccaggac aattgggggc      180

cctctcctta cagctacact cctaggaaag accaccatca atgattacca ggtgatcagg      240

atgcccttct ctcatctgtc tacctacagc ctggtttggg tcatggcagc agtggtgctg      300

tgcacagcac aagtgcaagt ggtgacccag gatgaaagag agcagctgta cacacctgct      360

tccttaaaat gctctctgca aaatgcccag gaagccctca ttgtgacatg gcagaaaaag      420

aaagctgtaa gcccagaaaa catggtcacc ttcagcgaga accatggggt ggtgatccag      480

cctgcctata aggacaagat aaacattacc cagctgggac tccaaaactc aaccatcacc      540

ttctggaata tcaccctgga ggatgaaggg tgttacatgt gtctcttcaa tacctttggt      600

tttgggaaga tctcaggaac ggcctgcctc accgtctatg tacagcccat agtatccctt      660

cactacaaat tctctgaaga ccacctaaat atcacttgct ctgccactgc ccgcccagcc      720

cccatggtct tctggaaggt ccctcggtca gggattgaaa atagtacagt gactctgtct      780

cacccaaatg ggaccacgtc tgttaccagc atcctccata tcaaagaccc taagaatcag      840

gtggggaagg aggtgatctg ccaggtgctg cacctgggga ctgtgaccga ctttaagcaa      900

accgtcaaca aaggctattg gttttcagtt ccgctattgc taagcattgt ttccctggta      960

attcttctcg tcctaatctc aatcttactg tactggaaac gtcaccggaa tcaggaccga     1020

gagccctaaa taagtcacac agcaccctga aagtgattcc ctggtctact tgaatttgac     1080

acaagagaaa agcaggagga aaaggggcca ttctccaaag gacctgaaag agcaaaagag     1140

gtgggagcga aagccttaag gatcccacga ctttttactg ccatctgagc tactcagtgt     1200

ttgaatccca agaggaagtc agtttacctc tcaggtctgt tgtaggactt gattttgtaa     1260

agcaatgcca tgttatgtgg ttgaaagggc actggactta gttagtatca ggagcactga     1320

gctcacagac tgacttgggc tcctactggt ggggacctct gttagtcact ttacctcatc     1380

caaagtataa aggaattgga ccaaataatt taccacatag ctctaaaact taatttaaaa     1440

tgtaattcca gaaaaaaaaa gggaataagc aaagggggaa gaattgaaag agagagagaa     1500

gaaagaatac agagagctta ccttttgcct ttctgttgat gttacatctc ttcttcctat     1560

gttcttaggt ctatgagtct gtttccccat catttggtat ctagtccagt tcctgcttac     1620

tgctttgcta atagctggcc ttgctagaat ccttggtttc actgctgttc ttcatgtgct     1680

tctatgagat ttactccaac acaaatagga ctgaatttat tgtgaagtaa cattggcaat     1740

cttaacttat tcatttaact tatttttata gctagataaa tattgttagt cttagacaat     1800

agctcacatt ttttgagaag catgccctcc ctgtccattt gtcttataac atgacccagc     1860

cctattttac gtcattctaa attcagcctc atataatgaa aatacattat gaaaacagat     1920

gtttaggaga tttcctgtat agcagtcagc caattcatat gctttgtctc tgctggcttc     1980

tttttccatg cgttaacttt tcccaatagc agaggaggca aatatgagca tacaatccct     2040

ttgttctaaa gatattgttc cagctagtgg aatgatgttg aatctttaat aaccataatt     2100

agttgctttt tcagtatctt ctgctttgtc tgtgtctatc cagtggccta ggaattaaag     2160

tgtaagttgt tttcgctgtt aaattggata tttatatata tatatagcaa gattttcatg     2220

tgttatttaa ttctgtattg tttcttatat ttgtagtaaa atattgaaca attaaaagtg     2280

ttgactccaa aaaaaaaaaa a                                               2301


<210>  1448
<211>  2226
<212>  DNA
<213>  homo sapiens

<400>  1448
aaacggagtg ggagaagggg gctagcgagg aggaagaggc gggaggtgcg gcaggggcac       60

aggtgacgct cctcccgcct gcctagcaga gctccaggcg cacatccgca gtcagccacc      120

tcgcgcgcgc ctccaggagc aaggatggag aggctggtga tcaggatgcc cttctctcat      180

ctgtctacct acagcctggt ttgggtcatg gcagcagtgg tgctgtgcac agcacaagtg      240

caagtggtga cccaggatga aagagagcag ctgtacacac ctgcttcctt aaaatgctct      300

ctgcaaaatg cccaggaagc cctcattgtg acatggcaga aaaagaaagc tgtaagccca      360

gaaaacatgg tcaccttcag cgagaaccat ggggtggtga tccagcctgc ctataaggac      420

aagataaaca ttacccagct gggactccaa aactcaacca tcaccttctg gaatatcacc      480

ctggaggatg aagggtgtta catgtgtctc ttcaatacct ttggttttgg gaagatctca      540

ggaacggcct gcctcaccgt ctatgtacag cccatagtat cccttcacta caaattctct      600

gaagaccacc taaatatcac ttgctctgcc actgcccgcc cagcccccat ggtcttctgg      660

aaggtccctc ggtcagggat tgaaaatagt acagtgactc tgtctcaccc aaatgggacc      720

acgtctgtta ccagcatcct ccatatcaaa gaccctaaga atcaggtggg gaaggaggtg      780

atctgccagg tgctgcacct ggggactgtg accgacttta agcaaaccgt caacaaaggc      840

tattggtttt cagttccgct attgctaagc attgtttccc tggtaattct tctcgtccta      900

atctcaatct tactgtactg gaaacgtcac cggaatcagg accgagagcc ctaaataagt      960

cacacagcac cctgaaagtg attccctggt ctacttgaat ttgacacaag agaaaagcag     1020

gaggaaaagg ggccattctc caaaggacct gaaagagcaa aagaggtggg agcgaaagcc     1080

ttaaggatcc cacgactttt tactgccatc tgagctactc agtgtttgaa tcccaagagg     1140

aagtcagttt acctctcagg tctgttgtag gacttgattt tgtaaagcaa tgccatgtta     1200

tgtggttgaa agggcactgg acttagttag tatcaggagc actgagctca cagactgact     1260

tgggctccta ctggtgggga cctctgttag tcactttacc tcatccaaag tataaaggaa     1320

ttggaccaaa taatttacca catagctcta aaacttaatt taaaatgtaa ttccagaaaa     1380

aaaaagggaa taagcaaagg gggaagaatt gaaagagaga gagaagaaag aatacagaga     1440

gcttaccttt tgcctttctg ttgatgttac atctcttctt cctatgttct taggtctatg     1500

agtctgtttc cccatcattt ggtatctagt ccagttcctg cttactgctt tgctaatagc     1560

tggccttgct agaatccttg gtttcactgc tgttcttcat gtgcttctat gagatttact     1620

ccaacacaaa taggactgaa tttattgtga agtaacattg gcaatcttaa cttattcatt     1680

taacttattt ttatagctag ataaatattg ttagtcttag acaatagctc acattttttg     1740

agaagcatgc cctccctgtc catttgtctt ataacatgac ccagccctat tttacgtcat     1800

tctaaattca gcctcatata atgaaaatac attatgaaaa cagatgttta ggagatttcc     1860

tgtatagcag tcagccaatt catatgcttt gtctctgctg gcttcttttt ccatgcgtta     1920

acttttccca atagcagagg aggcaaatat gagcatacaa tccctttgtt ctaaagatat     1980

tgttccagct agtggaatga tgttgaatct ttaataacca taattagttg ctttttcagt     2040

atcttctgct ttgtctgtgt ctatccagtg gcctaggaat taaagtgtaa gttgttttcg     2100

ctgttaaatt ggatatttat atatatatat agcaagattt tcatgtgtta tttaattctg     2160

tattgtttct tatatttgta gtaaaatatt gaacaattaa aagtgttgac tccaaaaaaa     2220

aaaaaa                                                                2226


<210>  1449
<211>  3795
<212>  DNA
<213>  homo sapiens

<400>  1449
atctgtgatt ggctgaacgg accgacccgg aagggtggat gctctcagct ggctggcggg       60

aagattttac tcccgagtag cggaaagatc tgctcgaggc ctgggtgctt tggtgtcgga      120

gatccgagag tcggagatcg gagagtcgga cacaggacag tcggacaccg gacagtcaaa      180

caccggagag ttagaccggg cttctcggtg gggagaggct ctgggataac tactgttaca      240

gctttgaagg gtcaagggtg tgcgcttttt gtttcatcct tccctttcct gctgcagggc      300

gaggccggtc tgtagcggat cacttccttt cgcccacaca ttggcggagg agaaaccgga      360

aagttaatca ctgccctgct ctgagaactc gggcctttag gggcacgttc gcctgctgac      420

cggtcttctg atctccccat tcttttccat gcaggaggat tggccaccaa agcctgttta      480

ttagcagctg ccatttgttg aaagaaattt ggattatttt agaaacaaat ttggaaagaa      540

aaagaatggc gtccgtttca gctctaactg aggaactgga ttctataacc agtgagctac      600

atgcagtaga aattcaaatt caagaactta cggaaaggca acaagagctt attcagaaaa      660

aaaaagtcct gacaaagaaa ataaagcagt gtttagagga ttctgatgcc ggggcaagca      720

atgaatatga ttcttcacct gccgcttgga ataaagaaga ttttccatgg tctggtaaag      780

ttaaagatat tctgcaaaat gtctttaaac tggaaaagtt cagaccactt cagcttgaaa      840

ctattaacgt aacaatggct ggaaaggagg tatttcttgt tatgcctaca ggaggtggaa      900

agagcttatg ttaccagtta ccagcattat gttcagatgg ttttacactc gtcatttgcc      960

cattgatctc tcttatggaa gaccaattaa tggttttaaa acaattagga atttcagcaa     1020

ccatgttaaa tgcttctagt tctaaggagc atgttaaatg ggttcatgct gaaatggtaa     1080

ataaaaactc cgagttaaag ctgatttatg tgactccaga gaaaattgca aaaagcaaaa     1140

tgtttatgtc aagactagag aaagcctatg aagcaaggag atttactcga attgctgtgg     1200

atgaagttca ctgctgtagt cagtggggac atgatttcag acctgattat aaggcacttg     1260

gtatcttaaa gcggcagttc cctaacgcat cactaattgg gctgactgca actgcaacaa     1320

atcacgtttt gacggatgct cagaaaattt tgtgcattga aaagtgtttt acttttacag     1380

cttcttttaa taggccaaat ctatattatg aggttcggca gaagccctca aacactgaag     1440

attttattga ggatattgta aagctcatta atgggagata caaagggcaa tcaggaatca     1500

tatattgttt ttctcagaaa gactctgaac aagttacggt tagtttgcag aatctgggaa     1560

ttcatgcagg tgcttaccat gccaatttgg agccagaaga taagaccaca gttcatagaa     1620

aatggtcagc caatgaaatt caggtagtag tggcaactgt tgcatttggt atgggaattg     1680

ataagccaga tgtgaggttt gttatccatc attcaatgag taaatccatg gaaaattatt     1740

accaagagag tggacgtgca ggtcgagatg acatgaaagc agactgtatt ttgtactacg     1800

gctttggaga tatattcaga ataagttcaa tggtggtgat ggaaaatgtg ggacagcaga     1860

agctttatga gatggtatca tactgtcaaa acataagcaa atgtcgtcgt gtgttgatgg     1920

ctcaacattt tgatgaagta tggaactcag aagcatgtaa caaaatgtgc gataactgct     1980

gtaaagacag tgcatttgaa agaaagaaca taacagagta ctgcagagat ctaatcaaga     2040

tcctgaagca ggcagaggaa ctgaatgaaa aactcactcc attgaaactg attgattctt     2100

ggatgggaaa gggtgcagca aaactgagag tagcaggtgt tgtggctccc acacttcctc     2160

gtgaagatct ggagaagatt attgcacact ttctaataca gcagtatctt aaagaagact     2220

acagttttac agcttatgct accatttcgt atttgaaaat aggacctaaa gctaatcttc     2280

tgaacaatga ggcacatgct attactatgc aagtgacaaa gtccacgcag aactctttca     2340

gggctgaatc gtctcaaact tgtcattctg aacaaggtga taaaaagatg gaggaaaaaa     2400

attcaggcaa cttccagaag aaggctgcaa acatgcttca gcaatctggt tctaagaata     2460

caggagctaa gaaaagaaaa atcgatgatg cctgatatga atgttactaa attttctaat     2520

taaagatggt ttatgcatgt atatgccatt atttttgtag ttagacaata gtttttaaaa     2580

gaatttcata gatattttat atgtatggat ctatattttc agagcttatc tctgaagatc     2640

taaacttttg agaatgtttg aaaattagag atcatgaatt atataatttt ccagtataaa     2700

acaagggaaa aatttttatg taaaaccctt taaatgtaaa atatttgaga ataagttcat     2760

acaatcgtct taagtttttt atgcctttat atacttagct atattttttc ttttgacata     2820

actatctttt tgaaagcaat attatactga cagaggctca ctgagtgata ctttaagtta     2880

aatatgtaga tcaaggatgt ccaatctttt ggcttccctg agccacattg gaagaagaat     2940

tgtcttgggc cgcacataaa atatgctaac actgatgata gctgatgagc ttaaaaaaaa     3000

aattgcaaga aaaatctcat gttttaagaa agtttacaaa aaatgtaaaa tatttgagaa     3060

taagttcatg taattgtctt aagtttttta tgcctttata tacttagcta tattttttct     3120

tttgacataa ccatcttttt gaaagcaata ttatactgac agaggttcac tgagtgatac     3180

tttaagttaa atatgtagat cagggatgtc caatcttttg gcttccctga gccacattgg     3240

aagaagaatt gtcttgggcc gcacataaaa tatgctaaca ctgacgatag ctgatgagct     3300

taaaaaaaaa aaaattgcaa gaaaaatctc atgttttaag aaagtttaca gatttgtgtt     3360

gggctgcatt caaagctgtt ctgggctgca ttagacccgt gggctagagt tggacaagct     3420

tgtagatgat ttcaggttat aaaaccagaa gtacaattca acaaaaaagg agtaagtcat     3480

caatataaat attagcaaac gagatattgc tacatctcta tttaaagtaa aatacaaccg     3540

attttaaagt tcctgaaacc atagccatat tttgacattt cacaaagaat ggttctagtc     3600

tactagagta catttggcta agtagataac ttacctaaat ttgctccaaa gctaaatcac     3660

aagtaaacat atttatgttt aaaacacaga aataaataac ttaagatttt tatctaagcg     3720

gtcagtgttg tattggaaag atatatctat aaataaactt tgaactgatt tcaaacttaa     3780

aaaaaaaaaa aaaaa                                                      3795


<210>  1450
<211>  2620
<212>  DNA
<213>  homo sapiens

<400>  1450
agagcaggcg agtcgggcgg atcgggtggg tagagtggtg ccgtccggtt gtttggtggg       60

aggcacgtaa gaccgctctg ggcacggggg cgctcacctc actggctcgt tcggttctag      120

gagcagatcc ggggtagagg gaaaagagct ccgggccagg ggctgccgtc gccgccgtcg      180

gggagtcagc ccgccagccc gccagctcgt cagcccgcca gccagcgctt cgcgggccct      240

gtcggtcccg gtaagcgggc ctgcgcttac cggaaagagg agcgtaagat gaaagagtat      300

cagaccaaac attgtctggc ttgcactgta aaactagtta gctgaagacg acttctcagg      360

tttcttcagg atgcctgcag cacttgtgga gaatagccag gttatctgtg aagtgtgggc      420

cagtaatcta gaagaagaga tgaggaagat ccgagaaatc gtgctcagtt acagttatat      480

tgccatggac acagaatttc caggtgttgt ggtgcgacca attggtgaat ttcgtagttc      540

catagattac caatatcagc ttctgcggtg caatgttgac cttttaaaaa ttatccagct      600

gggccttaca ttcacaaatg agaagggaga gtatccttct ggaatcaata cttggcagtt      660

caatttcaaa tttaacctta cagaggacat gtactcccag gattccatag atctccttgc      720

taactcagga ctacagtttc agaagcatga agaggaaggg attgacacac tgcactttgc      780

agagctgctt atgacatcag gagtggttct ctgtgacaat gtcaaatggc tttcatttca      840

tagtggctat gattttggct atatggtaaa gttgcttaca gattctcgtt tgccagaaga      900

ggaacatgaa ttctttcata ttctgaacct tttcttccca tccatttatg atgtgaaata      960

cctgatgaag agctgcaaaa atcttaaggg aggtcttcag gaagttgctg atcagttgga     1020

tttgcagagg attggaaggc agcaccaggc aggctcagac tcactgctga caggaatggc     1080

tttctttagg atgaaagagt tgttttttga ggacagcatt gatgatgcca agtactgtgg     1140

gcggctctat ggcttaggca caggagtggc ccagaagcag aatgaggatg tggactctgc     1200

ccaggagaag atgagcatcc tggcgattat caacaacatg cagcagtgat ggcgccaggc     1260

tctgcagggt gggcctgatc ccagagtggt gcttactgtg ctgactgtgt acttatcttc     1320

cccaagagaa aatgcttctt ttgagcacac tgtacctacc atctgcattg agcagaaaga     1380

cttttgtttt actgaagaca aaagatgttt ttattttaga cccagaagag aggagtttgc     1440

tctgaatttg taaataagtc ttccccattc ctcatactcg agcctctcct ctctggttgc     1500

ctcctgccac cagcatccat ggctcatttg acaccttttt aaatatcagg acaagtctga     1560

aacaaagtag taaaatgtat ataactctta cctgttgtca ttctttttct tttaaatttg     1620

ttgctaatct ctgataatga agattcttac tctgattctc agctgagctg tgagggcttc     1680

cagggaaaat ggaacaaaat ggtgttctta ggtaatgggt tgtagatact gagtcttcct     1740

ttccttttct gacccttctc gaggacattt gctttcctca cacttttgta gtctctcttt     1800

acatattact atatggaaat gaattgctct gtgctgaaat ttgaagacca gataatgaaa     1860

ctgaaaagca aacaatttta ctgaatctgt ctacccttca ttcatgagaa ctccagaatg     1920

agtgttgacc actgaagcat cttttaagtc tgtgttccat tgtgccattc aggtttgctg     1980

tcacatatgc atcatctgaa atcatttgaa atttttgtac aataaaatat cctggatttg     2040

atcctgaagg aaactagtaa gatcagattt ttgggtcatg tctgttgtat tttcagtaat     2100

gtgatttcag atggtcatct ggattctccc acttctctac tccattattt ctctactttt     2160

ccttccagca aacctgaaac gtgagggaga tggattaatg tgagtaacag gaatgtgtct     2220

ttaaaaagct agagtggtta catttaatca ggcagtaaga taatttgggt tcttgagttg     2280

ttttggagta atatcccaca actggggtag gaagctcagg acttttttct ttaaagctag     2340

tcatttcaaa agcatattgt atttttttga atgactacag tatggacaat ttcaaaaacc     2400

aaaacccact ttggattggt ggaagtaaaa actggtaact cactcaagtg aatgaatggt     2460

cttgcatttt aaaagcttat gggaaactca atttgaaatg attagaaaat gtcaagtatt     2520

ataagctggt atttaagatg cttgtaaata ctatttatgt ttttaatttt gtaaaataaa     2580

gatttctttt taaccactgg caaaaaaaaa aaaaaaaaaa                           2620


<210>  1451
<211>  2719
<212>  DNA
<213>  homo sapiens

<400>  1451
gggccagcgg cgcggctgaa gcgagggcgg ggagggaaag cgagcggcgc ctgcgccccg       60

gcggtggacg ggcccggtcg tgggcgggga ttggggcgga gcctgaccgt tacgcgcagc      120

cccgcccccg cggcctcgtc gctcctgctg aggcggtagc cgcttttcgt cgactcttac      180

cggttggctg ggccagctgc gccgcggctc acagctgacg atgggggacc ccagcaagca      240

ggacatcttg accatcttca agcgcctccg ctcggtgccc actaacaagg tgtgttttga      300

ttgtggtgcc aaaaatccca gctgggcaag cataacctat ggagtgttcc tttgcattga      360

ttgctcaggg tcccaccggt cacttggtgt tcacttgagt tttattcgat ctacagagtt      420

ggattccaac tggtcatggt ttcagttgcg atgcatgcaa gtcggaggaa acgctagtgc      480

actgtggctt gatagttgtg tggttccacc tttgtcccct ccaccaaagg aggaagattt      540

ttttgcctct cacgtttctc ctgaggtgag tgacacagcg tgggcatcag caatagcaga      600

accatcttct ttaacatcaa ggcctgtgga aaccactttg gaaaataatg aaggtggaca      660

agagcaagga ccaagtgtgg aaggtcttaa tgtaccaaca aaggctactt tagaggtatc      720

ctctatcata aaaaagaaac caaatcaagc taaaaaaggc cttggggcca aaaaaggaag      780

tttgggagct cagaaactgg caaacacatg ctttaatgaa attgaaaaac aagctcaagc      840

tgcggataaa atgaaggagc aggaagacct ggccaaggtg gtatctaaag aagaatcaat      900

tgtttcatca ttacgattag cctataagga tcttgaaatt caaatgaaga aagacgaaaa      960

gatgaacatt agtggcaaaa aaaatgttga ctcagacaga ctcggcatgg gatttggaaa     1020

ttgcagaagt gttatttcac attcagtgac ttcagatatg cagaccatag agcaggaatc     1080

acccattatg gcaaaaccaa gaaaaaagta taatgatgac agtgacgatt catattttac     1140

ttccagctca agttactttg acgagccagt ggagttaagg agcagttctt tctctagctg     1200

ggatgacagt tcagattcct attggaaaaa agagaccagc aaagatactg aaacagttct     1260

gaaaaccaca ggctattcag acagacctac tgctcgccgc aagccagatt atgagccagt     1320

tgaaaataca gatgaggccc agaagaagtt tggcaatgtc aaggccattt catcagatat     1380

gtattttgga agacaatccc aggctgatta tgagaccagg gcccgcctag agaggctgtc     1440

ggcaagttcc tccataagct cggctgatct gttcgaggag ccgaggaagc agccagcagg     1500

gaactacagc ctgtccagtg tgctgcccaa cgcccccgac atggcgcagt tcaagcaggg     1560

agtgagatcg gttgctggaa aactctccgt ctttgctaat ggagtcgtga cttcaattca     1620

ggatcgctac ggttcttaat actgaagtca tgatgtgtat ttcctggaga aattcctctt     1680

taaatgaaca agtaaccaca tctcaggcgg cagtgaagtc cagatagttt tgcagattgt     1740

tttgctactt tttcatatgg tatatgtttc tgatttttaa tatttctttt gagaaattct     1800

gagttctgat gtaggagctt tcctgtgatt tctgtttcac gttccttcct gtcacaccct     1860

cctttggcgt ctctgtgtat atccttgctt tattttcttg gaacctttga tttcaacact     1920

gagggcctgg agacctcggc tcctcctgct cctgaaccag gaggcttcat gtgggggagg     1980

aggagaggtc tccatgtgac acatgggctc agggctgcca gaatcagcgg atgctggatg     2040

ggcctgcaga aacaacactc accacacaca cttccttcaa aagaccaaaa gtgactggtg     2100

tctcgtgtga cagattgctt catttatgtt tctacatagt aaggtgactg ccaaataata     2160

tttgaagtca tctgtctctt tgtaaattat tttatatgac ctataaattt aaaaatgttt     2220

ttcagtgagt gcttttaaca aacttaagct tctgccctgc caagggaatt aatgttatct     2280

tgtgaaaggt gttgctgttt gaattgatga gaaatggaag atgagaactc cctaagagtt     2340

ctcataataa atcatctcat cacaaatcaa tacggtatac agagttaaag tggaatgagg     2400

taagaagata cagctacaga aaatagttgc gtgtatggga gaacagtcat tgtaattggg     2460

tagttttgtt aataaatatt tttaaatctt gcttttcaga aattaccgaa tgtgtataaa     2520

caaataaaga aaaataattt agctgtgttt tagacagcat tagaatatat tgttcagcac     2580

agtaaaatat atttgaaatt tgataagcca aaaatgtggt tttgaatgaa tattttgtga     2640

atctttctta aaagctcaaa tttgtagact tctaaataga ataaacactt gcagcagatg     2700

gaaaaaaaaa aaaaaaaaa                                                  2719


<210>  1452
<211>  2851
<212>  DNA
<213>  homo sapiens

<400>  1452
gggccagcgg cgcggctgaa gcgagggcgg ggagggaaag cgagcggcgc ctgcgccccg       60

gcggtggacg ggcccggtcg tgggcgggga ttggggcgga gcctgaccgt tacgcgcagc      120

cccgcccccg cggcctcgtc gctcctgctg aggcggtagc cgcttttcgt cgactcttac      180

cggttggctg ggccagctgc gccgcggctc acagctgacg atgggggacc ccagcaagca      240

ggacatcttg accatcttca agcgcctccg ctcggtgccc actaacaagg tgtgttttga      300

ttgtggtgcc aaaaatccca gctgggcaag cataacctat ggagtgttcc tttgcattga      360

ttgctcaggg tcccaccggt cacttggtgt tcacttgagt tttattcgat ctacagagtt      420

ggattccaac tggtcatggt ttcagttgcg atgcatgcaa gtcggaggaa acgctagtgc      480

atcttccttt tttcatcaac atgggtgttc caccaatgac accaatgcca agtacaacag      540

tcgtgctgct cagctctata gggagaaaat caaatcgctc gcctctcaag caacacggaa      600

gcatggcact gatctgtggc ttgatagttg tgtggttcca cctttgtccc ctccaccaaa      660

ggaggaagat ttttttgcct ctcacgtttc tcctgaggtg agtgacacag cgtgggcatc      720

agcaatagca gaaccatctt ctttaacatc aaggcctgtg gaaaccactt tggaaaataa      780

tgaaggtgga caagagcaag gaccaagtgt ggaaggtctt aatgtaccaa caaaggctac      840

tttagaggta tcctctatca taaaaaagaa accaaatcaa gctaaaaaag gccttggggc      900

caaaaaagga agtttgggag ctcagaaact ggcaaacaca tgctttaatg aaattgaaaa      960

acaagctcaa gctgcggata aaatgaagga gcaggaagac ctggccaagg tggtatctaa     1020

agaagaatca attgtttcat cattacgatt agcctataag gatcttgaaa ttcaaatgaa     1080

gaaagacgaa aagatgaaca ttagtggcaa aaaaaatgtt gactcagaca gactcggcat     1140

gggatttgga aattgcagaa gtgttatttc acattcagtg acttcagata tgcagaccat     1200

agagcaggaa tcacccatta tggcaaaacc aagaaaaaag tataatgatg acagtgacga     1260

ttcatatttt acttccagct caagttactt tgacgagcca gtggagttaa ggagcagttc     1320

tttctctagc tgggatgaca gttcagattc ctattggaaa aaagagacca gcaaagatac     1380

tgaaacagtt ctgaaaacca caggctattc agacagacct actgctcgcc gcaagccaga     1440

ttatgagcca gttgaaaata cagatgaggc ccagaagaag tttggcaatg tcaaggccat     1500

ttcatcagat atgtattttg gaagacaatc ccaggctgat tatgagacca gggcccgcct     1560

agagaggctg tcggcaagtt cctccataag ctcggctgat ctgttcgagg agccgaggaa     1620

gcagccagca gggaactaca gcctgtccag tgtgctgccc aacgcccccg acatggcgca     1680

gttcaagcag ggagtgagat cggttgctgg aaaactctcc gtctttgcta atggagtcgt     1740

gacttcaatt caggatcgct acggttctta atactgaagt catgatgtgt atttcctgga     1800

gaaattcctc tttaaatgaa caagtaacca catctcaggc ggcagtgaag tccagatagt     1860

tttgcagatt gttttgctac tttttcatat ggtatatgtt tctgattttt aatatttctt     1920

ttgagaaatt ctgagttctg atgtaggagc tttcctgtga tttctgtttc acgttccttc     1980

ctgtcacacc ctcctttggc gtctctgtgt atatccttgc tttattttct tggaaccttt     2040

gatttcaaca ctgagggcct ggagacctcg gctcctcctg ctcctgaacc aggaggcttc     2100

atgtggggga ggaggagagg tctccatgtg acacatgggc tcagggctgc cagaatcagc     2160

ggatgctgga tgggcctgca gaaacaacac tcaccacaca cacttccttc aaaagaccaa     2220

aagtgactgg tgtctcgtgt gacagattgc ttcatttatg tttctacata gtaaggtgac     2280

tgccaaataa tatttgaagt catctgtctc tttgtaaatt attttatatg acctataaat     2340

ttaaaaatgt ttttcagtga gtgcttttaa caaacttaag cttctgccct gccaagggaa     2400

ttaatgttat cttgtgaaag gtgttgctgt ttgaattgat gagaaatgga agatgagaac     2460

tccctaagag ttctcataat aaatcatctc atcacaaatc aatacggtat acagagttaa     2520

agtggaatga ggtaagaaga tacagctaca gaaaatagtt gcgtgtatgg gagaacagtc     2580

attgtaattg ggtagttttg ttaataaata tttttaaatc ttgcttttca gaaattaccg     2640

aatgtgtata aacaaataaa gaaaaataat ttagctgtgt tttagacagc attagaatat     2700

attgttcagc acagtaaaat atatttgaaa tttgataagc caaaaatgtg gttttgaatg     2760

aatattttgt gaatctttct taaaagctca aatttgtaga cttctaaata gaataaacac     2820

ttgcagcaga tggaaaaaaa aaaaaaaaaa a                                    2851


<210>  1453
<211>  5105
<212>  DNA
<213>  homo sapiens

<400>  1453
gtcacgtgag ccccgccccc gcgccggcgc gctccgacgt gccctgtaac ttaccctccc       60

tcagaggcca gcctgcgggg acgggccggc cgcggccgta gccgtgtgaa cgctcttcgg      120

gctcgcgtcg tcgacccgca gccgcggggc ggactaagaa gggagccgcc tgctgcgagg      180

ccgccgggct cccggtttaa atgtgatact ggtgtagatc tccttgttct aagctatatt      240

catccaacaa gccataaagc cataatgtgg tataacatcc tttttgagag gtgaatatta      300

ttgaatgaaa atggctgaca gaagtgggaa gattattcca ggacaagtgt atattgaggt      360

ggaatatgat tatgaatatg aagcaaagga cagaaagatt gtgataaaac aaggggagag      420

gtacatcttg gtgaaaaaga ccaatgatga ctggtggcaa gtcaagccag atgaaaactc      480

caaagcgttt tatgtgccag cccagtatgt gaaggaggtc acgcgcaaag ctctcatgcc      540

acctgttaag caggtagctg gtctgccaaa taactccacg aaaataatgc agagtttgca      600

tcttcagaga tcaacagaaa atgtgaacaa attgcctgag ctttcaagtt tcggaaagcc      660

atcgtcatct gttcaaggaa caggtcttat tcgtgatgcc aatcagaatt ttggacccag      720

ttataatcaa ggtcagactg tcaacctaag cctggacctg acccataata acggaaagtt      780

taacaatgac tcacattctc ctaaagtttc cagccagaat aggacacgct catttggtca      840

ttttcccggt ccagagttct tggatgtaga gaaaactagc ttctcccagg aacaatcttg      900

tgattccgca ggagaaggct ctgaaagaat acatcaagat tctgaatctg gtgatgaact      960

tagcagcagc tccactgaac agataagggc aaccacacct ccaaatcaag gaaggccaga     1020

ttctcctgtc tatgctaacc ttcaagaact gaaaatatcc cagtctgctc ttcccccact     1080

tcctgggagc ccggcaattc agattaatgg agaatgggaa actcataaag acagctcagg     1140

gcgttgctat tactataaca gagggacaca ggaaagaact tggaaacctc ctcgttggac     1200

tcgggatgca agcatcagca aaggagattt ccaaaatcca ggggatcaag agcttctttc     1260

atcggaagaa aactactaca gcacttctta cagccagtca gatagtcagt gtggttctcc     1320

tccaaggggt tggtcagaag agttggatga acgtgggcat accttatata ccagtgacta     1380

tactaatgaa aagtggctca agcatgttga tgatcaaggt agacaatatt actacagtgc     1440

agacggatct cggtcagaat gggaattgcc aaagtataat gcttcatccc agcagcaaag     1500

agaaataatt aaaagtagga gcctggacag gcggctgcaa gaaccaatag tattaacaaa     1560

gtggagacat agcaccattg tattggacac taatgataag gaatctccaa ctgcctcaaa     1620

accctgcttt cctgaaaatg agtcttctcc ctcctcacca aagcaccaag atacagccag     1680

cagtccaaag gatcaagaga aatatggatt attaaatgta acaaaaattg ctgaaaatgg     1740

gaaaaaggtt cgaaagaact ggttgtcttc ttgggcggtg ttgcagggtt catctttact     1800

ttttaccaaa actcaaggaa gtagcacaag ttggtttggc agtaatcagt ccaaaccaga     1860

gttcacagtg gacctcaagg gggcaacaat tgagatggct tcaaaggata aatccagcaa     1920

aaagaatgta tttgagctga aaactcgtca aggaacagaa ctgctaattc agtctgacaa     1980

tgacactgtt attaatgatt ggtttaaagt tcttagtagt acaatcaata atcaggcagt     2040

agaaactgat gaaggaattg aagaggagat accggattca ccaggaatag aaaagcatga     2100

taaagaaaag gaacaaaagg atcccaaaaa gcttcgttcc tttaaagtat ctagcataga     2160

ttcttcagaa cagaaaaaaa ccaagaaaaa cttaaagaag tttcttacac gacgccccac     2220

tttgcaagct gttcgtgaaa aaggttatat taaagatcag gtatttggat ccaatctcgc     2280

taatctgtgt cagagagaga atggcacagt accaaagttt gtgaagttat gtattgaaca     2340

tgttgaagaa catggtttgg atattgatgg gatatacaga gtaagtggca acctcgcagt     2400

gatccagaaa ctaaggtttg cagtcaatca tgatgagaaa ttggacttga atgacagtaa     2460

atgggaagat attcatgtca ttactggagc cctcaaaatg ttttttcgag aattaccaga     2520

acctcttttt acatttaatc attttaatga ttttgttaat gcaattaagc aagaaccaag     2580

acagcgagtc gctgctgtta aggacctaat cagacagttg ccaaagccaa accaagacac     2640

aatgcagatt cttttccgac atctcagaag agttatagaa aatggagaga aaaatcgaat     2700

gacctatcag agtatagcaa ttgtttttgg tcccactcta ttaaaaccag aaaaagagac     2760

tggtaatata gcagttcata ctgtgtacca gaatcagatt gtagaattaa ttcttctgga     2820

actgagttcc atcttcggac gttgattctt actgaagaca acctgtggaa tagaagctgg     2880

attccatcag atttcaaatg tttatacaca atgtatttta ttttttggac caagcagtga     2940

ctctttgatt ttgcactttt tttttgaggg atcagaaggg aaggggagag tcgagatgtg     3000

tgttaggccc tcatatttgc tgctttgttg caagttgata taactgcgtg taattatgaa     3060

ttcattttat cctgaatgtt tgcatttcat actctgaatt tcagtaaaaa tcaaaactta     3120

aaattctaac cagtcatata cactggataa tttggtaaga aaactgtatt ttttttccct     3180

gaaattggat aatgtacttt cttctcaaga ttcatgactt gatagaacaa tactttcagt     3240

tatgttgcaa aggctcttgg gcattttaaa caaaatgaag tatatccatt ttgaaacctg     3300

tgtatttctt tttcggggtt tctgcatgca gtggcagtct taagtgccaa aattcattat     3360

aaccccaaaa taaccccttg atgaaggctt gctgtctttt actgtgttac acagcatcct     3420

tactggatat cttagttgct tgtttgggca gcacactaat attacttaaa acactgtgat     3480

atactggagt tttagttagc ggaagtcagt tcagggcatt ttagggctgt cttgctatac     3540

tgaattgtag ctaacaatcc taattatatc tagtaccata ctgagttatt ggtatgaccc     3600

tgtggaaaca cacattattt tatgtaaata taggctaaag acttaatgtc ctttagcttg     3660

tgtatataat tgtgttgtat agtctcagag tacattctaa ccctacattt ctaatcattg     3720

ttattggtaa tcttttctgt gaatattagg tttcctccag aaatagtccg ttatttggga     3780

aagttaactg tgtgcacttt tagatattaa ctacatttac aggcaaatca ctgtaatgag     3840

aatggtactg gaaaaatact gaatagactt gctaaatggc acatgcacta caagaggaac     3900

cttttgggtt atttaatatg tacagaaaac attagaaaaa atttattaca gaattctaat     3960

tccagtatga atagtggaaa cccatctgta aattagatgg atgttggatg gaaaatgaca     4020

ttgctaaatt tgagaatttc tttttaccta ctaatgtaga ttgctttgta taataaaaca     4080

cagggtttgg aaggttttgt tacagggagc atggtctgtt gaagattttt aaaatgtatt     4140

tttctagatt aacttctgta catgaaatgt ctaataaaac tataagaggt ttagagattt     4200

ttccattgga aatgtgcatt ttggtttcta atttttttgt tttttcattt actggcatac     4260

tgttatacct catttttaaa aatcaactga atccaatatt tcctgtggca aataacactt     4320

tcctcatttc ataccttttc tcctctcttc catgccaaca tttctccacc cacaacgtac     4380

actttttatt tctccatcaa tatttgaaag cgagtgattt gtgaccagga tttttttttc     4440

ttagggttgc atttataatt tacagattgc cttccttggg aacaagtatt tttttgtatg     4500

atctgtctaa aaacctctca cctgaatttt gtggtagaaa gtctgtattt gttgttgtga     4560

gcgtgttaaa ttgataacaa accaaactac ttgatagcta aagcagattg tttcgggtgg     4620

ggagaaaaag ccctaaatca gaatgtttat atttgcctaa agatgtcctt aataatacaa     4680

tatgctttag atcttgctta tttagtgatt gtataccagg aaaacaatta gactcaaatc     4740

agtgatgttc ttgttcttgg tgttcatgaa catatatcaa agattaaaat tgtcctgtgt     4800

ttcttgtttc aaggtacgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgaagtct     4860

taaatgtttt attagtctac agctaatcag tttattgtaa tattgtatgt acagtgagat     4920

taatgtcttg cgttttcatc ctttgtgaat taaaaattct cacttgtttt gtaataacaa     4980

agctagtaat attttcctgt cttgacagct tggttttata gtagaaaata tattaaaagc     5040

tgaaataaat tatcagtgga attttatttg ttagtaagtc ttccttcata atgtcattga     5100

aaaag                                                                 5105


<210>  1454
<211>  5105
<212>  DNA
<213>  homo sapiens

<400>  1454
gtcacgtgag ccccgccccc gcgccggcgc gctccgacgt gccctgtaac ttaccctccc       60

tcagaggcca gcctgcgggg acgggccggc cgcggccgta gccgtgtgaa cgctcttcgg      120

gctcgcgtcg tcgacccgca gccgcggggc ggactaagaa gggagccgcc tgctgcgagg      180

ccgccgggct cccggtttaa atgtgatact ggtgtagatc tccttgttct aagctatatt      240

catccaacaa gccataaagc cataatgtgg tataacatcc tttttgagag gtgaatatta      300

ttgaatgaaa atggctgaca gaagtgggaa gattattcca ggacaagtgt atattgaggt      360

ggaatatgat tatgaatatg aagcaaagga cagaaagatt gtgataaaac aaggggagag      420

gtacatcttg gtgaaaaaga ccaatgatga ctggtggcaa gtcaagccag atgaaaactc      480

caaagcgttt tatgtgccag cccagtatgt gaaggaggtc acgcgcaaag ctctcatgcc      540

acctgttaag caggtagctg gtctgccaaa taactccacg aaaataatgc agagtttgca      600

tcttcagaga tcaacagaaa atgtgaacaa attgcctgag ctttcaagtt tcggaaagcc      660

atcgtcatct gttcaaggaa caggtcttat tcgtgatgcc aatcagaatt ttggacccag      720

ttataatcaa ggtcagactg tcaacctaag cctggacctg acccataata acggaaagtt      780

taacaatgac tcacattctc ctaaagtttc cagccagaat aggacacgct catttggtca      840

ttttcccggt ccagagttct tggatgtaga gaaaactagc ttctcccagg aacaatcttg      900

tgattccgca ggagaaggct ctgaaagaat acatcaagat tctgaatctg gtgatgaact      960

tagcagcagc tccactgaac agataagggc aaccacacct ccaaatcaag gaaggccaga     1020

ttctcctgtc tatgctaacc ttcaagaact gaaaatatcc cagtctgctc ttcccccact     1080

tcctgggagc ccggcaattc agattaatgg agaatgggaa actcataaag acagctcagg     1140

gcgttgctat tactataaca gagggacaca ggaaagaact tggaaacctc ctcgttggac     1200

tcgggatgca agcatcagca aaggagattt ccaaaatcca ggggatcaag agcttctttc     1260

atcggaagaa aactactaca gcacttctta cagccagtca gatagtcagt gtggttctcc     1320

tccaaggggt tggtcagaag agttggatga acgtgggcat accttatata ccagtgacta     1380

tactaatgaa aagtggctca agcatgttga tgatcaaggt agacaatatt actacagtgc     1440

agacggatct cggtcagaat gggaattgcc aaagtataat gcttcatccc agcagcaaag     1500

agaaataatt aaaagtagga gcctggacag gcggctgcaa gaaccaatag tattaacaaa     1560

gtggagacat agcaccattg tattggacac taatgataag gaatctccaa ctgcctcaaa     1620

accctgcttt cctgaaaatg agtcttctcc ctcctcacca aagcaccaag atacagccag     1680

cagtccaaag gatcaagaga aatatggatt attaaatgta acaaaaattg ctgaaaatgg     1740

gaaaaaggtt cgaaagaact ggttgtcttc ttgggcggtg ttgcagggtt catctttact     1800

ttttaccaaa actcaaggaa gtagcacaag ttggtttggc agtaatcagt ccaaaccaga     1860

gttcacagtg gacctcaagg gggcaacaat tgagatggct tcaaaggata aatccagcaa     1920

aaagaatgta tttgagctga aaactcgtca aggaacagaa ctgctaattc agtctgacaa     1980

tgacactgtt attaatgatt ggtttaaagt tcttagtagt acaatcaata atcaggcagt     2040

agaaactgat gaaggaattg aagaggagat accggattca ccaggaatag aaaagcatga     2100

taaagaaaag gaacaaaagg atcccaaaaa gcttcgttcc tttaaagtat ctagcataga     2160

ttcttcagaa cagaaaaaaa ccaagaaaaa cttaaagaag tttcttacac gacgccccac     2220

tttgcaagct gttcgtgaaa aaggttatat taaagatcag gtatttggat ccaatctcgc     2280

taatctgtgt cagagagaga atggcacagt accaaagttt gtgaagttat gtattgaaca     2340

tgttgaagaa catggtttgg atattgatgg gatatacaga gtaagtggca acctcgcagt     2400

gatccagaaa ctaaggtttg cagtcaatca tgatgagaaa ttggacttga atgacagtaa     2460

atgggaagat attcatgtca ttactggagc cctcaaaatg ttttttcgag aattaccaga     2520

acctcttttt acatttaatc attttaatga ttttgttaat gcaattaagc aagaaccaag     2580

acagcgagtc gctgctgtta aggacctaat cagacagttg ccaaagccaa accaagacac     2640

aatgcagatt cttttccgac atctcagaag agttatagaa aatggagaga aaaatcgaat     2700

gacctatcag agtatagcaa ttgtttttgg tcccactcta ttaaaaccag aaaaagagac     2760

tggtaatata gcagttcata ctgtgtacca gaatcagatt gtagaattaa ttcttctgga     2820

actgagttcc atcttcggac gttgattctt actgaagaca acctgtggaa tagaagctgg     2880

attccatcag atttcaaatg tttatacaca atgtatttta ttttttggac caagcagtga     2940

ctctttgatt ttgcactttt tttttgaggg atcagaaggg aaggggagag tcgagatgtg     3000

tgttaggccc tcatatttgc tgctttgttg caagttgata taactgcgtg taattatgaa     3060

ttcattttat cctgaatgtt tgcatttcat actctgaatt tcagtaaaaa tcaaaactta     3120

aaattctaac cagtcatata cactggataa tttggtaaga aaactgtatt ttttttccct     3180

gaaattggat aatgtacttt cttctcaaga ttcatgactt gatagaacaa tactttcagt     3240

tatgttgcaa aggctcttgg gcattttaaa caaaatgaag tatatccatt ttgaaacctg     3300

tgtatttctt tttcggggtt tctgcatgca gtggcagtct taagtgccaa aattcattat     3360

aaccccaaaa taaccccttg atgaaggctt gctgtctttt actgtgttac acagcatcct     3420

tactggatat cttagttgct tgtttgggca gcacactaat attacttaaa acactgtgat     3480

atactggagt tttagttagc ggaagtcagt tcagggcatt ttagggctgt cttgctatac     3540

tgaattgtag ctaacaatcc taattatatc tagtaccata ctgagttatt ggtatgaccc     3600

tgtggaaaca cacattattt tatgtaaata taggctaaag acttaatgtc ctttagcttg     3660

tgtatataat tgtgttgtat agtctcagag tacattctaa ccctacattt ctaatcattg     3720

ttattggtaa tcttttctgt gaatattagg tttcctccag aaatagtccg ttatttggga     3780

aagttaactg tgtgcacttt tagatattaa ctacatttac aggcaaatca ctgtaatgag     3840

aatggtactg gaaaaatact gaatagactt gctaaatggc acatgcacta caagaggaac     3900

cttttgggtt atttaatatg tacagaaaac attagaaaaa atttattaca gaattctaat     3960

tccagtatga atagtggaaa cccatctgta aattagatgg atgttggatg gaaaatgaca     4020

ttgctaaatt tgagaatttc tttttaccta ctaatgtaga ttgctttgta taataaaaca     4080

cagggtttgg aaggttttgt tacagggagc atggtctgtt gaagattttt aaaatgtatt     4140

tttctagatt aacttctgta catgaaatgt ctaataaaac tataagaggt ttagagattt     4200

ttccattgga aatgtgcatt ttggtttcta atttttttgt tttttcattt actggcatac     4260

tgttatacct catttttaaa aatcaactga atccaatatt tcctgtggca aataacactt     4320

tcctcatttc ataccttttc tcctctcttc catgccaaca tttctccacc cacaacgtac     4380

actttttatt tctccatcaa tatttgaaag cgagtgattt gtgaccagga tttttttttc     4440

ttagggttgc atttataatt tacagattgc cttccttggg aacaagtatt tttttgtatg     4500

atctgtctaa aaacctctca cctgaatttt gtggtagaaa gtctgtattt gttgttgtga     4560

gcgtgttaaa ttgataacaa accaaactac ttgatagcta aagcagattg tttcgggtgg     4620

ggagaaaaag ccctaaatca gaatgtttat atttgcctaa agatgtcctt aataatacaa     4680

tatgctttag atcttgctta tttagtgatt gtataccagg aaaacaatta gactcaaatc     4740

agtgatgttc ttgttcttgg tgttcatgaa catatatcaa agattaaaat tgtcctgtgt     4800

ttcttgtttc aaggtacgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgaagtct     4860

taaatgtttt attagtctac agctaatcag tttattgtaa tattgtatgt acagtgagat     4920

taatgtcttg cgttttcatc ctttgtgaat taaaaattct cacttgtttt gtaataacaa     4980

agctagtaat attttcctgt cttgacagct tggttttata gtagaaaata tattaaaagc     5040

tgaaataaat tatcagtgga attttatttg ttagtaagtc ttccttcata atgtcattga     5100

aaaag                                                                 5105


<210>  1455
<211>  5282
<212>  DNA
<213>  homo sapiens

<400>  1455
ctcatttcca aggtcccctg aagtgctggc tcacctctgt ttcccaaagc acttgcttgc       60

ttgtctctcc tccctcccca gcatcctttt cactttcttc ccttataact tcttgcactc      120

tgtgtgcgtg tgtgtgtatg cgtgtgtgca tgtgcgtttc ttcttttttt ttatcctaac      180

gaatttgttt tgcaggtttt gaaaaggaaa aaccagcgtt atccaggatt gttaaattaa      240

ttcttatctg tttccacatc ttggaccgtg atctctgtgg ttttaaaatc ccatattttg      300

agtgggttcc gctgttgttt aagaaaagtt gctttaaacc tttgctctgc aagcacccga      360

agagaactca taaaaaggaa gacaacagca gatgcaatcg cggatgtggc ttagtccttg      420

cagctgcccc agagtgctgt ttggagtgta ccgtcctcag taatgaatcc agaagaacaa      480

atcgtgacat ggcttatatc tttgggagtt ttagagtccc ctaaaaagac catctgtgat      540

ccggaggagt ttttaaagtc ctcgctgaaa aatggggtag ttctgtgcaa actgatcaac      600

agactcatgc ctggctctgt ggaaaagttt tgtctggatc cccaaactga agctgactgc      660

atcaacaaca tcaatgactt cctgaaagga tgtgcaaccc tccaagtgga aatatttgat      720

cctgatgacc tttattcagg ggtcaatttc tccaaggtac tgagtactct tttagctgtc      780

aacaaagcaa cagaagatca gctatcagaa agaccatgtg gacgttcctc ttctcttagt      840

gctgctaata cttctcagac aaacccacag ggagcagttt ctagcacagt ttcagggctg      900

caaaggcagt caaagacagt ggagatgacg gaaaatggaa gtcatcagtt gatagtaaaa      960

gcaagattca actttaagca gactaatgag gatgaactgt cagtttgtaa gggggacatc     1020

atttacgtca cacgagttga agaaggaggc tggtgggaag gcacattaaa tgggagaaca     1080

ggctggttcc ccagtaatta tgtccgtgaa attaaatcca gtgagagacc tctctcccca     1140

aaagccgtca aaggatttga aactgctcca cttaccaaga attattatac tgtggtgtta     1200

cagaacatcc tggacactga aaaagaatat gctaaagaac ttcagtctct tcttgttact     1260

tacttaagac ccctgcagtc caataacaat ctgagtactg tggaggttac atctttactg     1320

ggaaacttcg aggaagtatg cacatttcaa cagacactct gccaagcctt ggaagaatgt     1380

tcaaagtttc cagaaaacca gcacaaagta ggaggttgtc tactgagtct catgcctcat     1440

tttaaatcta tgtatctggc ttactgtgca aaccatcctt cagctgtaaa tgtgctcact     1500

cagcacagtg atgagttgga acaattcatg gaaaatcaag gtgcatcgag cccaggtatc     1560

ctcattttaa caacaaacct cagcaaacca ttcatgcgac tggagaaata tgttactctc     1620

ttgcaagagt tagaacggca tatggaggat actcatccag atcatcagga tattctgaaa     1680

gcaatcgtag cattcaaaac tctcatgggg caatgtcaag atctgaggaa gagaaaacag     1740

ctggagttac agatactgtc cgaacctatt caggcatggg aaggagaaga tattaaaaac     1800

ttgggaaatg tgatttttat gtcacaagta atggtgcagt atggagcatg tgaggaaaaa     1860

gaggagcggt accttatgtt attttcaaat gtcctgataa tgttatctgc aagtcctcgg     1920

atgagtggct ttatctatca gggaaaaata ccaatagcag gaacggtggt gactagatta     1980

gatgaaattg aagggaatga ctgcacattt gaaatcactg gtaacacagt ggagagaatt     2040

gtggtccatt gtaacaacaa ccaggacttc caggaatggt tggagcagct gaacagactg     2100

atcagaggac ctgcctcttg cagttcatta tccaaaacct catcgtcatc atgtagtgct     2160

cattcttctt ttagctctac cggacagccc cgaggaccct tggagcctcc tcaaattata     2220

aaaccgtgga gtttaagttg tctacgacct gcacctccac ttagaccatc agcagcacta     2280

ggttataaag agaggatgtc ttatatctta aaggagtcta gtaaaagccc taaaacgatg     2340

aagaaatttc ttcataaaag gaagactgag agaaaaccat cggaggagga atatgtgatt     2400

aggaaaagta cagctgctct ggaagaggat gctcaaatcc ttaaagtgat cgaagcctac     2460

tgcaccagcg caaattttca acaaggccat ggctcaagta ctcgaaaaga ttccattcca     2520

caagtcctac tccctgagga agagaaactc atcattgaag aaaccagaag caacggccag     2580

accatcatgg aagaaaagag ccttgttgat actgtttacg ccttgaagga cgaggtcaga     2640

gaactgaagc aggaaaataa aagaatgaag caatgcctgg aagaagaact gaaatcaaga     2700

agggacctag aaaagctggt gcggaggctt ttgaagcaaa cagatgagtg tattcgaggc     2760

gagtccagta gcaagacctc aattcttcca taaccatcac tgtgccactg ggtggagtgt     2820

gccttcaggg catcttgaaa tgtcccgctg aatgatttga ctcagtttgc tcacttcttt     2880

ggcttttgtt ttgtgtttga gtctctctct ctctctccct ctctcttctc tttctctccc     2940

cgctgtgtgc atatgtgtgt gcgtgcacgt gcgcgcttgg gcatttgctg ttgtttggtt     3000

attggttggt tgttcatttt ttttttcaac aggtgaaaaa gcaggaagtg gtggtagaga     3060

tggcctcaga gtcttttcca ttcagtaaga aagagaaagg gaatgcaggc cagttactta     3120

aaaggtcttc agattgcctt cagttcacag tgcctctgca acagccattg ccctcaggtc     3180

acattctttg ggctggctgc ccttgcaaag cagctggcca aggcttatta aatgtgaacc     3240

caacttttcc ccagggcttt cctgtacctg caagcctctt agtacttaat ttaccgaagg     3300

caaatcttcc agactatggc ttgagtagga tgaaagacaa acacatctgc ccaatgatcc     3360

agctgccctt ccttagacca tcacatgcct cccctcaatc acaggtttta aaattactgc     3420

cctatgttgt ctataagacc aagaaaactg tagtaccctt attccttttg tgtcatgtaa     3480

attgtaactc aggggggcag aagctctggt cacccacacc aacaccaaat ccatcagcaa     3540

attctactgg acaatcctcc cttttagtag cagagttgac cgccttttcc cattgcatga     3600

taggtttctt tccctcattc tgcctagtgt gtaagttttc tatttcccca gtacttttag     3660

ccaaccttac caagtggtgt gtaaactagt atgtatgtgc tttgcttact ttttaaaaaa     3720

atgtagttag actgtgagga gttactttat gtacgttgca tattcaaact gtgatgtttt     3780

atccttcaaa acaatctgca ttaagaagat attgtgccct actagacagc tttcattcac     3840

tttattactc tctcatatat gctgtgagaa gttgtaatat taattggcct ctttgggtgg     3900

gactctaagc agtatttgca gaaatatgct tctggtccaa cttgtacatc cagaacaaaa     3960

gggcccctct agtagctgtg tgctggatta ttcaggactg attaactcaa gttgctcatt     4020

gaatcacatc atccacttta tcccagaaac tagaactgtg agaaaccagg tttagaagac     4080

agtcacagaa cagcacacat ccaaattcag cgccattgaa agttggccta aggctcagtg     4140

ccactcaccc ctccctcccc aaaagacaag agaaatttgg ccagatgggg aaggtcactg     4200

gaaattgagg ccaaagggct gatcagaatt gcctttataa tatatttgat ggatgcctat     4260

aaatgtgggt tttgcaaata ttgtttaaaa accaaacttg aagccaggca tggtggccca     4320

cacctgtggt cccagctact caggaggctg aggtgggagg atcatttgag cccaggaggt     4380

caaggctgca gtgagctgtg atgacaccac tgcactccaa cctaggtaac agagagacac     4440

ctctgtctct gaaaaaacaa aacttgaagt ttgaaacccc cagcttgctg aggagccctt     4500

tttatttttg gtactgagag tctcaaggtc ccatagctac atggtacagg gctgttgtct     4560

gcttgctgca cagcagaaat tacaccatcc acaggaaatg gactattttt gcagtccaac     4620

atcagccaac cacacacagc cgtgtttgga agctgaagag taaagaaatt tctaggaatg     4680

gctgttgttc tgttttttag cacagccatt tagatataac atccttcact taaaaattaa     4740

aaacatcagt actaccacca ccaccaacaa catcaacaca gatcttcaca tctgcccatt     4800

ctgtggttag tcaatggctt gcaataaatg tgcaaactgc atctatagga aacatttttg     4860

tgattacgga atactttagt tgattgctga aaatattgaa aggtcttcat tttacagtga     4920

tgagtacata tgcatgtttc ggggacttgg cccttctgat gaggggccct cggtactctg     4980

gataacgaag cttgtgcaga gtggtaacca tgcttacaca ctaaactata atataaagga     5040

aatgaagcca tgttaatctg agagcagtgt cgccatagtt gtgttgttta caatactcta     5100

taaatgggtt cctgttgccc tgtaattaaa ctgctgcccg tagaggcctt tcagttcctt     5160

ttctgtcctt ccccttctta acacaagctc aaattttcta acttgttttt attttgaaga     5220

cttttaaaat ggacattttc aatacataaa aataaacagt gctttataaa aaaaaaaaaa     5280

aa                                                                    5282


<210>  1456
<211>  5282
<212>  DNA
<213>  homo sapiens

<400>  1456
ctcatttcca aggtcccctg aagtgctggc tcacctctgt ttcccaaagc acttgcttgc       60

ttgtctctcc tccctcccca gcatcctttt cactttcttc ccttataact tcttgcactc      120

tgtgtgcgtg tgtgtgtatg cgtgtgtgca tgtgcgtttc ttcttttttt ttatcctaac      180

gaatttgttt tgcaggtttt gaaaaggaaa aaccagcgtt atccaggatt gttaaattaa      240

ttcttatctg tttccacatc ttggaccgtg atctctgtgg ttttaaaatc ccatattttg      300

agtgggttcc gctgttgttt aagaaaagtt gctttaaacc tttgctctgc aagcacccga      360

agagaactca taaaaaggaa gacaacagca gatgcaatcg cggatgtggc ttagtccttg      420

cagctgcccc agagtgctgt ttggagtgta ccgtcctcag taatgaatcc agaagaacaa      480

atcgtgacat ggcttatatc tttgggagtt ttagagtccc ctaaaaagac catctgtgat      540

ccggaggagt ttttaaagtc ctcgctgaaa aatggggtag ttctgtgcaa actgatcaac      600

agactcatgc ctggctctgt ggaaaagttt tgtctggatc cccaaactga agctgactgc      660

atcaacaaca tcaatgactt cctgaaagga tgtgcaaccc tccaagtgga aatatttgat      720

cctgatgacc tttattcagg ggtcaatttc tccaaggtac tgagtactct tttagctgtc      780

aacaaagcaa cagaagatca gctatcagaa agaccatgtg gacgttcctc ttctcttagt      840

gctgctaata cttctcagac aaacccacag ggagcagttt ctagcacagt ttcagggctg      900

caaaggcagt caaagacagt ggagatgacg gaaaatggaa gtcatcagtt gatagtaaaa      960

gcaagattca actttaagca gactaatgag gatgaactgt cagtttgtaa gggggacatc     1020

atttacgtca cacgagttga agaaggaggc tggtgggaag gcacattaaa tgggagaaca     1080

ggctggttcc ccagtaatta tgtccgtgaa attaaatcca gtgagagacc tctctcccca     1140

aaagccgtca aaggatttga aactgctcca cttaccaaga attattatac tgtggtgtta     1200

cagaacatcc tggacactga aaaagaatat gctaaagaac ttcagtctct tcttgttact     1260

tacttaagac ccctgcagtc caataacaat ctgagtactg tggaggttac atctttactg     1320

ggaaacttcg aggaagtatg cacatttcaa cagacactct gccaagcctt ggaagaatgt     1380

tcaaagtttc cagaaaacca gcacaaagta ggaggttgtc tactgagtct catgcctcat     1440

tttaaatcta tgtatctggc ttactgtgca aaccatcctt cagctgtaaa tgtgctcact     1500

cagcacagtg atgagttgga acaattcatg gaaaatcaag gtgcatcgag cccaggtatc     1560

ctcattttaa caacaaacct cagcaaacca ttcatgcgac tggagaaata tgttactctc     1620

ttgcaagagt tagaacggca tatggaggat actcatccag atcatcagga tattctgaaa     1680

gcaatcgtag cattcaaaac tctcatgggg caatgtcaag atctgaggaa gagaaaacag     1740

ctggagttac agatactgtc cgaacctatt caggcatggg aaggagaaga tattaaaaac     1800

ttgggaaatg tgatttttat gtcacaagta atggtgcagt atggagcatg tgaggaaaaa     1860

gaggagcggt accttatgtt attttcaaat gtcctgataa tgttatctgc aagtcctcgg     1920

atgagtggct ttatctatca gggaaaaata ccaatagcag gaacggtggt gactagatta     1980

gatgaaattg aagggaatga ctgcacattt gaaatcactg gtaacacagt ggagagaatt     2040

gtggtccatt gtaacaacaa ccaggacttc caggaatggt tggagcagct gaacagactg     2100

atcagaggac ctgcctcttg cagttcatta tccaaaacct catcgtcatc atgtagtgct     2160

cattcttctt ttagctctac cggacagccc cgaggaccct tggagcctcc tcaaattata     2220

aaaccgtgga gtttaagttg tctacgacct gcacctccac ttagaccatc agcagcacta     2280

ggttataaag agaggatgtc ttatatctta aaggagtcta gtaaaagccc taaaacgatg     2340

aagaaatttc ttcataaaag gaagactgag agaaaaccat cggaggagga atatgtgatt     2400

aggaaaagta cagctgctct ggaagaggat gctcaaatcc ttaaagtgat cgaagcctac     2460

tgcaccagcg caaattttca acaaggccat ggctcaagta ctcgaaaaga ttccattcca     2520

caagtcctac tccctgagga agagaaactc atcattgaag aaaccagaag caacggccag     2580

accatcatgg aagaaaagag ccttgttgat actgtttacg ccttgaagga cgaggtcaga     2640

gaactgaagc aggaaaataa aagaatgaag caatgcctgg aagaagaact gaaatcaaga     2700

agggacctag aaaagctggt gcggaggctt ttgaagcaaa cagatgagtg tattcgaggc     2760

gagtccagta gcaagacctc aattcttcca taaccatcac tgtgccactg ggtggagtgt     2820

gccttcaggg catcttgaaa tgtcccgctg aatgatttga ctcagtttgc tcacttcttt     2880

ggcttttgtt ttgtgtttga gtctctctct ctctctccct ctctcttctc tttctctccc     2940

cgctgtgtgc atatgtgtgt gcgtgcacgt gcgcgcttgg gcatttgctg ttgtttggtt     3000

attggttggt tgttcatttt ttttttcaac aggtgaaaaa gcaggaagtg gtggtagaga     3060

tggcctcaga gtcttttcca ttcagtaaga aagagaaagg gaatgcaggc cagttactta     3120

aaaggtcttc agattgcctt cagttcacag tgcctctgca acagccattg ccctcaggtc     3180

acattctttg ggctggctgc ccttgcaaag cagctggcca aggcttatta aatgtgaacc     3240

caacttttcc ccagggcttt cctgtacctg caagcctctt agtacttaat ttaccgaagg     3300

caaatcttcc agactatggc ttgagtagga tgaaagacaa acacatctgc ccaatgatcc     3360

agctgccctt ccttagacca tcacatgcct cccctcaatc acaggtttta aaattactgc     3420

cctatgttgt ctataagacc aagaaaactg tagtaccctt attccttttg tgtcatgtaa     3480

attgtaactc aggggggcag aagctctggt cacccacacc aacaccaaat ccatcagcaa     3540

attctactgg acaatcctcc cttttagtag cagagttgac cgccttttcc cattgcatga     3600

taggtttctt tccctcattc tgcctagtgt gtaagttttc tatttcccca gtacttttag     3660

ccaaccttac caagtggtgt gtaaactagt atgtatgtgc tttgcttact ttttaaaaaa     3720

atgtagttag actgtgagga gttactttat gtacgttgca tattcaaact gtgatgtttt     3780

atccttcaaa acaatctgca ttaagaagat attgtgccct actagacagc tttcattcac     3840

tttattactc tctcatatat gctgtgagaa gttgtaatat taattggcct ctttgggtgg     3900

gactctaagc agtatttgca gaaatatgct tctggtccaa cttgtacatc cagaacaaaa     3960

gggcccctct agtagctgtg tgctggatta ttcaggactg attaactcaa gttgctcatt     4020

gaatcacatc atccacttta tcccagaaac tagaactgtg agaaaccagg tttagaagac     4080

agtcacagaa cagcacacat ccaaattcag cgccattgaa agttggccta aggctcagtg     4140

ccactcaccc ctccctcccc aaaagacaag agaaatttgg ccagatgggg aaggtcactg     4200

gaaattgagg ccaaagggct gatcagaatt gcctttataa tatatttgat ggatgcctat     4260

aaatgtgggt tttgcaaata ttgtttaaaa accaaacttg aagccaggca tggtggccca     4320

cacctgtggt cccagctact caggaggctg aggtgggagg atcatttgag cccaggaggt     4380

caaggctgca gtgagctgtg atgacaccac tgcactccaa cctaggtaac agagagacac     4440

ctctgtctct gaaaaaacaa aacttgaagt ttgaaacccc cagcttgctg aggagccctt     4500

tttatttttg gtactgagag tctcaaggtc ccatagctac atggtacagg gctgttgtct     4560

gcttgctgca cagcagaaat tacaccatcc acaggaaatg gactattttt gcagtccaac     4620

atcagccaac cacacacagc cgtgtttgga agctgaagag taaagaaatt tctaggaatg     4680

gctgttgttc tgttttttag cacagccatt tagatataac atccttcact taaaaattaa     4740

aaacatcagt actaccacca ccaccaacaa catcaacaca gatcttcaca tctgcccatt     4800

ctgtggttag tcaatggctt gcaataaatg tgcaaactgc atctatagga aacatttttg     4860

tgattacgga atactttagt tgattgctga aaatattgaa aggtcttcat tttacagtga     4920

tgagtacata tgcatgtttc ggggacttgg cccttctgat gaggggccct cggtactctg     4980

gataacgaag cttgtgcaga gtggtaacca tgcttacaca ctaaactata atataaagga     5040

aatgaagcca tgttaatctg agagcagtgt cgccatagtt gtgttgttta caatactcta     5100

taaatgggtt cctgttgccc tgtaattaaa ctgctgcccg tagaggcctt tcagttcctt     5160

ttctgtcctt ccccttctta acacaagctc aaattttcta acttgttttt attttgaaga     5220

cttttaaaat ggacattttc aatacataaa aataaacagt gctttataaa aaaaaaaaaa     5280

aa                                                                    5282


<210>  1457
<211>  9609
<212>  DNA
<213>  homo sapiens

<400>  1457
atggcccata acgcgggcgc cgcggccgcc gccggcaccc acagcgccaa gagcggcggc       60

tccgaggcgg ctctcaagga gggtggaagc gccgccgcgc tgtcctcctc ctcctcctcc      120

tccgcggcgg cagcggcggc atcctcttcc tcctcgtcgg gcccgggctc ggccatggag      180

acggggctgc tccccaacca caaactgaaa accgttggcg aagcccccgc cgcgccgccc      240

caccagcagc accaccacca ccaccatgcc caccaccacc accaccatgc ccaccacctc      300

caccaccacc acgcactaca gcagcagcta aaccagttcc agcagcagca gcagcagcag      360

caacagcagc agcagcagca gcagcaacag caacatccca tttccaacaa caacagcttg      420

ggcggcgcgg gcggcggcgc gcctcagccc ggccccgaca tggagcagcc gcaacatgga      480

ggcgccaagg acagtgctgc gggcggccag gccgaccccc cgggcccgcc gctgctgagc      540

aagccgggcg acgaggacga cgcgccgccc aagatggggg agccggcggg cggccgctac      600

gagcacccgg gcttgggcgc cctgggcacg cagcagccgc cggtcgccgt gcccgggggc      660

ggcggcggcc cggcggccgt cccggagttt aataattact atggcagcgc tgcccctgcg      720

agcggcggcc ccggcggccg cgctgggcct tgctttgatc aacatggcgg acaacaaagc      780

cccgggatgg ggatgatgca ctccgcctcc gccgccgccg ccggggcccc cggcagcatg      840

gaccccctgc agaactccca cgaagggtac cccaacagcc agtgcaacca ttatccgggc      900

tacagccggc ccggcgcggg cggcggcggc ggcggcggcg gcggaggagg aggaggcagc      960

ggaggaggag gaggaggagg aggagcagga gcaggaggag caggagcggg agctgtggcg     1020

gcggcggccg cggcggcggc ggcagcagca ggaggcggcg gcggcggcgg ctatgggggc     1080

tcgtccgcgg ggtacggggt gctgagctcc ccccggcagc agggcggcgg catgatgatg     1140

ggccccgggg gcggcggggc cgcgagcctc agcaaggcgg ccgccggctc ggcggcgggg     1200

ggcttccagc gcttcgccgg ccagaaccag cacccgtcgg gggccacccc gaccctcaat     1260

cagctgctca cctcgcccag ccccatgatg cggagctacg gcggcagcta ccccgagtac     1320

agcagcccca gcgcgccgcc gccgccgccg tcgcagcccc agtcccaggc ggcggcggcg     1380

ggggcggcgg cgggcggcca gcaggcggcc gcgggcatgg gcttgggcaa ggacatgggc     1440

gcccagtacg ccgctgccag cccggcctgg gcggccgcgc aacaaaggag tcacccggcg     1500

atgagccccg gcacccccgg accgaccatg ggcagatccc agggcagccc aatggatcca     1560

atggtgatga agagacctca gttgtatggc atgggcagta accctcattc tcagcctcag     1620

cagagcagtc cgtacccagg aggttcctat ggccctccag gcccacagcg gtatccaatt     1680

ggcatccagg gtcggactcc cggggccatg gccggaatgc agtaccctca gcagcagatg     1740

ccacctcagt atggacagca aggtgtgagt ggttactgcc agcagggcca acagccatat     1800

tacagccagc agccgcagcc cccgcacctc ccaccccagg cgcagtatct gccgtcccag     1860

tcccagcaga ggtaccagcc gcagcaggac atgtctcagg aaggctatgg aactagatct     1920

caacctcctc tggcccccgg aaaacctaac catgaagact tgaacttaat acagcaagaa     1980

agaccatcaa gtttaccaga tctgtctggc tccattgatg acctccccac gggaacggaa     2040

gcaactttga gctcagcagt cagtgcatcc gggtccacga gcagccaagg ggatcagagc     2100

aacccggcgc agtcgccttt ctccccacat gcgtcccctc atctctccag catcccgggg     2160

ggcccatctc cctctcctgt tggctctcct gtaggaagca accagtctcg atctggccca     2220

atctctcctg caagtatccc aggtagtcag atgcctccgc agccacccgg gagccagtca     2280

gaatccagtt cccatcccgc cttgagccag tcaccaatgc cacaggaaag aggttttatg     2340

gcaggcacac aaagaaaccc tcagatggct cagtatggac ctcaacagac aggaccatcc     2400

atgtcgcctc atccttctcc tgggggccag atgcatgctg gaatcagtag ctttcagcag     2460

agtaactcaa gtgggactta cggtccacag atgagccagt atggaccaca aggtaactac     2520

tccagacccc cagcgtatag tggggtgccc agtgcaagct acagcggccc agggcccggt     2580

atgggtatca gtgccaacaa ccagatgcat ggacaagggc caagccagcc atgtggtgct     2640

gtgcccctgg gacgaatgcc atcagctggg atgcagaaca gaccatttcc tggaaatatg     2700

agcagcatga cccccagttc tcctggcatg tctcagcagg gagggccagg aatggggccg     2760

ccaatgccaa ctgtgaaccg taaggcacag gaggcagccg cagcagtgat gcaggctgct     2820

gcgaactcag cacaaagcag gcaaggcagt ttccccggca tgaaccagag tggacttatg     2880

gcttccagct ctccctacag ccagcccatg aacaacagct ctagcctgat gaacacgcag     2940

gcgccgccct acagcatggc gcccgccatg gtgaacagct cggcagcatc tgtgggtctt     3000

gcagatatga tgtctcctgg tgaatccaaa ctgcccctgc ctctcaaagc agacggcaaa     3060

gaagaaggca ctccacagcc cgagagcaag tcaaagaagt ccagctcctc caccactact     3120

ggggagaaga tcacgaaggt gtacgagctg gggaatgagc cagagagaaa gctctgggtc     3180

gaccgatacc tcaccttcat ggaagagaga ggctctcctg tctcaagtct gcctgccgtg     3240

ggcaagaagc ccctggacct gttccgactc tacgtctgcg tcaaagagat cgggggtttg     3300

gcccaggtta ataaaaacaa gaagtggcgt gagctggcaa ccaacctaaa cgttggcacc     3360

tcaagcagtg cagcgagctc cctgaaaaag cagtatattc agtacctgtt tgcctttgag     3420

tgcaagatcg aacgtgggga ggagcccccg ccggaagtct tcagcaccgg ggacaccaaa     3480

aagcagccca agctccagcc gccatctcct gctaactcgg gatccttgca aggcccacag     3540

accccccagt caactggcag caattccatg gcagaggttc caggtgacct gaagccacct     3600

accccagcct ccacccctca cggccagatg actccaatgc aaggtggaag aagcagtaca     3660

atcagtgtgc acgacccatt ctcagatgtg agtgattcat ccttcccgaa acggaactcc     3720

atgactccaa acgcccccta ccagcagggc atgagcatgc ccgatgtgat gggcaggatg     3780

ccctatgagc ccaacaagga cccctttggg ggaatgagaa aagtgcctgg aagcagcgag     3840

ccctttatga cgcaaggaca gatgcccaac agcagcatgc aggacatgta caaccaaagt     3900

ccctccggag caatgtctaa cctgggcatg gggcagcgcc agcagtttcc ctatggagcc     3960

agttacgacc gaaggcatga accttatggg cagcagtatc caggccaagg ccctccctcg     4020

ggacagccgc cgtatggagg gcaccagccc ggcctgtacc cacagcagcc gaattacaaa     4080

cgccatatgg acggcatgta cgggccccca gccaagcgcc acgagggcga catgtacaac     4140

atgcagtaca gcagccagca gcaggagatg tacaaccagt atggaggctc ctactcgggc     4200

ccggaccgca ggcccatcca gggccagtac ccgtatccct acagcaggga gaggatgcag     4260

ggcccggggc agatccagac acacggaatc ccgcctcaga tgatgggcgg cccgctgcag     4320

tcgtcctcca gtgaggggcc tcagcagaat atgtgggcag cacgcaatga tatgccttat     4380

ccctaccaga acaggcaggg ccctggcggc cctacacagg cgccccctta cccaggcatg     4440

aaccgcacag acgatatgat ggtacccgat cagaggataa atcatgagag ccagtggcct     4500

tctcacgtca gccagcgtca gccttatatg tcgtcctcag cctccatgca gcccatcaca     4560

cgcccaccac agccgtccta ccagacgcca ccgtcactgc caaatcacat ctccagggcg     4620

cccagcccag cgtccttcca gcgctccctg gagaaccgca tgtctccaag caagtctcct     4680

tttctgccgt ctatgaagat gcagaaggtc atgcccacgg tccccacatc ccaggtcacc     4740

gggccaccac cccaaccacc cccaatcaga agggagatca cctttcctcc tggctcagta     4800

gaagcatcac aaccagtctt gaaacaaagg cgaaagatta cctccaaaga tatcgttact     4860

cctgaggcgt ggcgtgtgat gatgtccctt aaatcaggtc ttttggctga gagtacgtgg     4920

gctttggaca ctattaatat tcttctgtat gatgacagca ctgttgctac tttcaatctc     4980

tcccagttgt ctggatttct cgaactttta gtcgagtact ttagaaaatg cctgattgac     5040

atttttggaa ttcttatgga atatgaagtg ggagacccca gccaaaaagc acttgatcac     5100

aacgcagcaa ggaaggatga cagccagtcc ttggcagacg attctgggaa agaggaggaa     5160

gatgctgaat gtattgatga cgacgaggaa gacgaggagg atgaggagga agacagcgag     5220

aagacagaaa gcgatgaaaa gagcagcatc gctctgactg ccccggacgc cgctgcagac     5280

ccaaaggaga agcccaagca agccagtaag ttcgacaagc tgccaataaa gatagtcaaa     5340

aagaacaacc tgtttgttgt tgaccgatct gacaagttgg ggcgtgtgca ggagttcaat     5400

agtggccttc tgcactggca gctcggcggg ggtgacacca ccgagcacat tcagactcac     5460

tttgagagca agatggaaat tcctcctcgc aggcgcccac ctcccccctt aagctccgca     5520

ggtagaaaga aagagcaaga aggcaaaggc gactctgaag agcagcaaga gaaaagcatc     5580

atagcaacca tcgatgacgt cctctctgct cggccagggg cattgcctga agacgcaaac     5640

cctgggcccc agaccgaaag cagtaagttt ccctttggta tccagcaagc caaaagtcac     5700

cggaacatca agctgctgga ggacgagccc aggagccgag acgagactcc tctgtgtacc     5760

atcgcgcact ggcaggactc gctggctaag cgatgcatct gtgtgtccaa tattgtccgt     5820

agcttgtcat tcgtgcctgg caatgatgcc gaaatgtcca aacatccagg cctggtgctg     5880

atcctgggga agctgattct tcttcaccac gagcatccag agagaaagcg agcaccgcag     5940

acctatgaga aagaggagga tgaggacaag ggggtggcct gcagcaaaga tgagtggtgg     6000

tgggactgcc tcgaggtctt gagggataac acgttggtca cgttggccaa catttccggg     6060

cagctagact tgtctgctta cacggaaagc atctgcttgc caattttgga tggcttgctg     6120

cactggatgg tgtgcccgtc tgcagaggca caagatccct ttccaactgt gggacccaac     6180

tcggtcctgt cgcctcagag acttgtgctg gagaccctct gtaaactcag tatccaggac     6240

aataatgtgg acctgatctt ggccactcct ccatttagtc gtcaggagaa attctatgct     6300

acattagtta ggtacgttgg ggatcgcaaa aacccagtct gtcgagaaat gtccatggcg     6360

cttttatcga accttgccca aggggacgca ctagcagcaa gggccatagc tgtgcagaaa     6420

ggaagcattg gaaacttgat aagcttccta gaggatgggg tcacgatggc ccagtaccag     6480

cagagccagc acaacctcat gcacatgcag cccccgcccc tggaaccacc tagcgtagac     6540

atgatgtgca gggcggccaa ggctttgcta gccatggcca gagtggacga aaaccgctcg     6600

gaattccttt tgcacgaggg ccggttgctg gatatctcga tatcagctgt cctgaactct     6660

ctggttgcat ctgtcatctg tgatgtactg tttcagattg ggcagttatg acataagtga     6720

gaaggcaagc atgtgtgagt gaagattaga gggtcacata taactggctg ttttctgttc     6780

ttgtttatcc agcgtaggaa gaaggaaaag aaaatctttg ctcctctgcc ccattcacta     6840

tttaccaatt gggaattaaa gaaataatta atttgaacag ttatgaaatt aatatttgct     6900

gtctgtgtgt ataagtacat cctttggggt tttttttttc tctttttttt aaccaaagtt     6960

gctgtctagt gcattcaaag gtcacttttt gttcttcaca gatcttttta atgttctttc     7020

ccatgttgta ttgcattttt gggggaagca aattgacttt aaagaaaaaa gttgtggcaa     7080

aagatgctaa gatgcgaaaa tttcaccaca ctgagtcaaa aaggtgaaaa attatccatt     7140

tcctatgcgt tttactcctc agagaatgaa aaaaactgca tcccatcacc caaagttctg     7200

tgcaatagaa atttctacag atacaggtat aggggctcaa ggaggtatgt cggtcagtag     7260

tcaaaactat gaaatgatac tggtttctcc acaggaatat ggttccatta ggctgggagc     7320

aaaaacaatg ttttttaaga ttgagaatac atacctgaca acgatccgga aactgctcct     7380

caccactccc gtcatgcctg ctgtcggcgt ttgaccttcc acgtgacagt tcttcacaat     7440

tcctttcatc attttttaaa tatttttttt actgcctatg ggctgtgatg tatatagaag     7500

ttgtacatta aacataccct catttttttc ttttcttttt tttttttttt tttagtacaa     7560

agttttagtt tctttttcat gatgtggtaa ctacgaagtg atggtagatt taaataattt     7620

tttattttta ttttatatat tttttcatta gggccatatc tccaaaaaaa gaaagaaaaa     7680

atacaaaaaa caaaaacaaa aaaaaaagag ggtaatgtac aagtttctgt atgtataaag     7740

tcatgctcga tttcaggaga gcagctgatc acaatttgct tcatgaatca aggtgtggaa     7800

atggttatat atggattgat ttagaaaatg gttaccagta cagtcaaaaa agagaaaatg     7860

aaaaaaatac aactaaaagg aagaaacaca acttcaaaga tttttcagtg atgagaatcc     7920

acatttgtat ttcaagataa tgtagtttaa aaaaaaaaaa aagaaaaaaa cttgatgtaa     7980

attcctcctt ttcctctggc ttaatgaata tcatttattc agtataaaat ctttatatgt     8040

tccacatgtt aagaataaat gtacattaaa tcttgttaag cactgtgatg ggtgttcttg     8100

aatactgttc tagtttcctt aaagtggttt cctagtaatc aagttattta caagaaatag     8160

gggaatgcag cagtgtattc acattataaa accctacatt tggaagagac ctttaggggt     8220

tacctacttt agagtgggga gcaacagttt gattttctca aattacttag ctaattagtc     8280

tttctttgaa gcaattaact ctaacgacat tgaggtatga tcattttcag tatttatggg     8340

aggtggctgc tgacccactt gaggtgagat ctcagaagct taactggcct gaaaatgtaa     8400

cattctgcct tttactaact ccatcttagt ttaatcaaag ttcaatctat tccttgtttc     8460

ttctgtgtgc ctcagagtta ttttgcattt agtttactcc accgtgtata atatttatac     8520

tgtgcaatgt taaaaaagaa tctgttatat tgtatgtggt gtacatagtg caaagtgatg     8580

atttctattt cagggcatat tatggttctc atattccttc ctacctggtg cacagtagct     8640

ttttaatact agtcacttct aatttaaact ttctcttcct gggtcattga ctgttactgt     8700

gtaataatcg atttctttga aactgctgca taattatgct gttagtggac ctctacctct     8760

tctcttccct ctcccaatca cagtatactc agaatcccca gcccctcgca tacattgtgt     8820

cggttcacat tactcacagt aatatatgga agagttagac aagaacatgc agttacagtc     8880

attgtgagac gtgactctcc agtgtcacga ggaaaaaaat catcttttct gcaaacagtc     8940

tctcatctgt caactcccac attactgagt caaacagtct tcttacataa caatgcaacc     9000

aaatatatgt tgaattaaag acccatttat aattctgctt taaatacatc tgcttgctaa     9060

gaacagattt cagtgctcca agcttcaaat atggagattt gtaagaggga attcaatatt     9120

attctaattt ctctcttaca gagtacaaat aaaaggtgta tacaaactcc gaacatatcc     9180

agtattccaa ttcctttgtc aatcagaaga gtaaaataat taacaaaaga ctgttgttat     9240

ggtttgcatt gtaaccgata cgcagagtct gaccgttggg caacaagttt ttctatcctg     9300

atgcgcaaca cagtctctag agactaatcc aggaagactt tagcctcctt tccatattct     9360

cacccccgaa tcaagattta cagaagccca cgaagaattt acagcctgct tgagatcatc     9420

ttgcctataa actgagttat tgctttgtcc taaaaattag tcggtttttt tttttctatg     9480

aggcttttca gaaatttaca ggatgcccag actttacatg tgtaccaaaa aaaaaaaaaa     9540

gataaaaaat aaaggtgcaa agaaagttta gtattttgga atggtgctat aaagttgaaa     9600

aaaaaaaaa                                                             9609


<210>  1458
<211>  9648
<212>  DNA
<213>  homo sapiens

<400>  1458
atggcccata acgcgggcgc cgcggccgcc gccggcaccc acagcgccaa gagcggcggc       60

tccgaggcgg ctctcaagga gggtggaagc gccgccgcgc tgtcctcctc ctcctcctcc      120

tccgcggcgg cagcggcggc atcctcttcc tcctcgtcgg gcccgggctc ggccatggag      180

acggggctgc tccccaacca caaactgaaa accgttggcg aagcccccgc cgcgccgccc      240

caccagcagc accaccacca ccaccatgcc caccaccacc accaccatgc ccaccacctc      300

caccaccacc acgcactaca gcagcagcta aaccagttcc agcagcagca gcagcagcag      360

caacagcagc agcagcagca gcagcaacag caacatccca tttccaacaa caacagcttg      420

ggcggcgcgg gcggcggcgc gcctcagccc ggccccgaca tggagcagcc gcaacatgga      480

ggcgccaagg acagtgctgc gggcggccag gccgaccccc cgggcccgcc gctgctgagc      540

aagccgggcg acgaggacga cgcgccgccc aagatggggg agccggcggg cggccgctac      600

gagcacccgg gcttgggcgc cctgggcacg cagcagccgc cggtcgccgt gcccgggggc      660

ggcggcggcc cggcggccgt cccggagttt aataattact atggcagcgc tgcccctgcg      720

agcggcggcc ccggcggccg cgctgggcct tgctttgatc aacatggcgg acaacaaagc      780

cccgggatgg ggatgatgca ctccgcctcc gccgccgccg ccggggcccc cggcagcatg      840

gaccccctgc agaactccca cgaagggtac cccaacagcc agtgcaacca ttatccgggc      900

tacagccggc ccggcgcggg cggcggcggc ggcggcggcg gcggaggagg aggaggcagc      960

ggaggaggag gaggaggagg aggagcagga gcaggaggag caggagcggg agctgtggcg     1020

gcggcggccg cggcggcggc ggcagcagca ggaggcggcg gcggcggcgg ctatgggggc     1080

tcgtccgcgg ggtacggggt gctgagctcc ccccggcagc agggcggcgg catgatgatg     1140

ggccccgggg gcggcggggc cgcgagcctc agcaaggcgg ccgccggctc ggcggcgggg     1200

ggcttccagc gcttcgccgg ccagaaccag cacccgtcgg gggccacccc gaccctcaat     1260

cagctgctca cctcgcccag ccccatgatg cggagctacg gcggcagcta ccccgagtac     1320

agcagcccca gcgcgccgcc gccgccgccg tcgcagcccc agtcccaggc ggcggcggcg     1380

ggggcggcgg cgggcggcca gcaggcggcc gcgggcatgg gcttgggcaa ggacatgggc     1440

gcccagtacg ccgctgccag cccggcctgg gcggccgcgc aacaaaggag tcacccggcg     1500

atgagccccg gcacccccgg accgaccatg ggcagatccc agggcagccc aatggatcca     1560

atggtgatga agagacctca gttgtatggc atgggcagta accctcattc tcagcctcag     1620

cagagcagtc cgtacccagg aggttcctat ggccctccag gcccacagcg gtatccaatt     1680

ggcatccagg gtcggactcc cggggccatg gccggaatgc agtaccctca gcagcaggac     1740

tctggagatg ccacatggaa agaaacattc tggttgatgc cacctcagta tggacagcaa     1800

ggtgtgagtg gttactgcca gcagggccaa cagccatatt acagccagca gccgcagccc     1860

ccgcacctcc caccccaggc gcagtatctg ccgtcccagt cccagcagag gtaccagccg     1920

cagcaggaca tgtctcagga aggctatgga actagatctc aacctcctct ggcccccgga     1980

aaacctaacc atgaagactt gaacttaata cagcaagaaa gaccatcaag tttaccagat     2040

ctgtctggct ccattgatga cctccccacg ggaacggaag caactttgag ctcagcagtc     2100

agtgcatccg ggtccacgag cagccaaggg gatcagagca acccggcgca gtcgcctttc     2160

tccccacatg cgtcccctca tctctccagc atcccggggg gcccatctcc ctctcctgtt     2220

ggctctcctg taggaagcaa ccagtctcga tctggcccaa tctctcctgc aagtatccca     2280

ggtagtcaga tgcctccgca gccacccggg agccagtcag aatccagttc ccatcccgcc     2340

ttgagccagt caccaatgcc acaggaaaga ggttttatgg caggcacaca aagaaaccct     2400

cagatggctc agtatggacc tcaacagaca ggaccatcca tgtcgcctca tccttctcct     2460

gggggccaga tgcatgctgg aatcagtagc tttcagcaga gtaactcaag tgggacttac     2520

ggtccacaga tgagccagta tggaccacaa ggtaactact ccagaccccc agcgtatagt     2580

ggggtgccca gtgcaagcta cagcggccca gggcccggta tgggtatcag tgccaacaac     2640

cagatgcatg gacaagggcc aagccagcca tgtggtgctg tgcccctggg acgaatgcca     2700

tcagctggga tgcagaacag accatttcct ggaaatatga gcagcatgac ccccagttct     2760

cctggcatgt ctcagcaggg agggccagga atggggccgc caatgccaac tgtgaaccgt     2820

aaggcacagg aggcagccgc agcagtgatg caggctgctg cgaactcagc acaaagcagg     2880

caaggcagtt tccccggcat gaaccagagt ggacttatgg cttccagctc tccctacagc     2940

cagcccatga acaacagctc tagcctgatg aacacgcagg cgccgcccta cagcatggcg     3000

cccgccatgg tgaacagctc ggcagcatct gtgggtcttg cagatatgat gtctcctggt     3060

gaatccaaac tgcccctgcc tctcaaagca gacggcaaag aagaaggcac tccacagccc     3120

gagagcaagt caaagaagtc cagctcctcc accactactg gggagaagat cacgaaggtg     3180

tacgagctgg ggaatgagcc agagagaaag ctctgggtcg accgatacct caccttcatg     3240

gaagagagag gctctcctgt ctcaagtctg cctgccgtgg gcaagaagcc cctggacctg     3300

ttccgactct acgtctgcgt caaagagatc gggggtttgg cccaggttaa taaaaacaag     3360

aagtggcgtg agctggcaac caacctaaac gttggcacct caagcagtgc agcgagctcc     3420

ctgaaaaagc agtatattca gtacctgttt gcctttgagt gcaagatcga acgtggggag     3480

gagcccccgc cggaagtctt cagcaccggg gacaccaaaa agcagcccaa gctccagccg     3540

ccatctcctg ctaactcggg atccttgcaa ggcccacaga ccccccagtc aactggcagc     3600

aattccatgg cagaggttcc aggtgacctg aagccaccta ccccagcctc cacccctcac     3660

ggccagatga ctccaatgca aggtggaaga agcagtacaa tcagtgtgca cgacccattc     3720

tcagatgtga gtgattcatc cttcccgaaa cggaactcca tgactccaaa cgccccctac     3780

cagcagggca tgagcatgcc cgatgtgatg ggcaggatgc cctatgagcc caacaaggac     3840

ccctttgggg gaatgagaaa agtgcctgga agcagcgagc cctttatgac gcaaggacag     3900

atgcccaaca gcagcatgca ggacatgtac aaccaaagtc cctccggagc aatgtctaac     3960

ctgggcatgg ggcagcgcca gcagtttccc tatggagcca gttacgaccg aaggcatgaa     4020

ccttatgggc agcagtatcc aggccaaggc cctccctcgg gacagccgcc gtatggaggg     4080

caccagcccg gcctgtaccc acagcagccg aattacaaac gccatatgga cggcatgtac     4140

gggcccccag ccaagcgcca cgagggcgac atgtacaaca tgcagtacag cagccagcag     4200

caggagatgt acaaccagta tggaggctcc tactcgggcc cggaccgcag gcccatccag     4260

ggccagtacc cgtatcccta cagcagggag aggatgcagg gcccggggca gatccagaca     4320

cacggaatcc cgcctcagat gatgggcggc ccgctgcagt cgtcctccag tgaggggcct     4380

cagcagaata tgtgggcagc acgcaatgat atgccttatc cctaccagaa caggcagggc     4440

cctggcggcc ctacacaggc gcccccttac ccaggcatga accgcacaga cgatatgatg     4500

gtacccgatc agaggataaa tcatgagagc cagtggcctt ctcacgtcag ccagcgtcag     4560

ccttatatgt cgtcctcagc ctccatgcag cccatcacac gcccaccaca gccgtcctac     4620

cagacgccac cgtcactgcc aaatcacatc tccagggcgc ccagcccagc gtccttccag     4680

cgctccctgg agaaccgcat gtctccaagc aagtctcctt ttctgccgtc tatgaagatg     4740

cagaaggtca tgcccacggt ccccacatcc caggtcaccg ggccaccacc ccaaccaccc     4800

ccaatcagaa gggagatcac ctttcctcct ggctcagtag aagcatcaca accagtcttg     4860

aaacaaaggc gaaagattac ctccaaagat atcgttactc ctgaggcgtg gcgtgtgatg     4920

atgtccctta aatcaggtct tttggctgag agtacgtggg ctttggacac tattaatatt     4980

cttctgtatg atgacagcac tgttgctact ttcaatctct cccagttgtc tggatttctc     5040

gaacttttag tcgagtactt tagaaaatgc ctgattgaca tttttggaat tcttatggaa     5100

tatgaagtgg gagaccccag ccaaaaagca cttgatcaca acgcagcaag gaaggatgac     5160

agccagtcct tggcagacga ttctgggaaa gaggaggaag atgctgaatg tattgatgac     5220

gacgaggaag acgaggagga tgaggaggaa gacagcgaga agacagaaag cgatgaaaag     5280

agcagcatcg ctctgactgc cccggacgcc gctgcagacc caaaggagaa gcccaagcaa     5340

gccagtaagt tcgacaagct gccaataaag atagtcaaaa agaacaacct gtttgttgtt     5400

gaccgatctg acaagttggg gcgtgtgcag gagttcaata gtggccttct gcactggcag     5460

ctcggcgggg gtgacaccac cgagcacatt cagactcact ttgagagcaa gatggaaatt     5520

cctcctcgca ggcgcccacc tcccccctta agctccgcag gtagaaagaa agagcaagaa     5580

ggcaaaggcg actctgaaga gcagcaagag aaaagcatca tagcaaccat cgatgacgtc     5640

ctctctgctc ggccaggggc attgcctgaa gacgcaaacc ctgggcccca gaccgaaagc     5700

agtaagtttc cctttggtat ccagcaagcc aaaagtcacc ggaacatcaa gctgctggag     5760

gacgagccca ggagccgaga cgagactcct ctgtgtacca tcgcgcactg gcaggactcg     5820

ctggctaagc gatgcatctg tgtgtccaat attgtccgta gcttgtcatt cgtgcctggc     5880

aatgatgccg aaatgtccaa acatccaggc ctggtgctga tcctggggaa gctgattctt     5940

cttcaccacg agcatccaga gagaaagcga gcaccgcaga cctatgagaa agaggaggat     6000

gaggacaagg gggtggcctg cagcaaagat gagtggtggt gggactgcct cgaggtcttg     6060

agggataaca cgttggtcac gttggccaac atttccgggc agctagactt gtctgcttac     6120

acggaaagca tctgcttgcc aattttggat ggcttgctgc actggatggt gtgcccgtct     6180

gcagaggcac aagatccctt tccaactgtg ggacccaact cggtcctgtc gcctcagaga     6240

cttgtgctgg agaccctctg taaactcagt atccaggaca ataatgtgga cctgatcttg     6300

gccactcctc catttagtcg tcaggagaaa ttctatgcta cattagttag gtacgttggg     6360

gatcgcaaaa acccagtctg tcgagaaatg tccatggcgc ttttatcgaa ccttgcccaa     6420

ggggacgcac tagcagcaag ggccatagct gtgcagaaag gaagcattgg aaacttgata     6480

agcttcctag aggatggggt cacgatggcc cagtaccagc agagccagca caacctcatg     6540

cacatgcagc ccccgcccct ggaaccacct agcgtagaca tgatgtgcag ggcggccaag     6600

gctttgctag ccatggccag agtggacgaa aaccgctcgg aattcctttt gcacgagggc     6660

cggttgctgg atatctcgat atcagctgtc ctgaactctc tggttgcatc tgtcatctgt     6720

gatgtactgt ttcagattgg gcagttatga cataagtgag aaggcaagca tgtgtgagtg     6780

aagattagag ggtcacatat aactggctgt tttctgttct tgtttatcca gcgtaggaag     6840

aaggaaaaga aaatctttgc tcctctgccc cattcactat ttaccaattg ggaattaaag     6900

aaataattaa tttgaacagt tatgaaatta atatttgctg tctgtgtgta taagtacatc     6960

ctttggggtt ttttttttct ctttttttta accaaagttg ctgtctagtg cattcaaagg     7020

tcactttttg ttcttcacag atctttttaa tgttctttcc catgttgtat tgcatttttg     7080

ggggaagcaa attgacttta aagaaaaaag ttgtggcaaa agatgctaag atgcgaaaat     7140

ttcaccacac tgagtcaaaa aggtgaaaaa ttatccattt cctatgcgtt ttactcctca     7200

gagaatgaaa aaaactgcat cccatcaccc aaagttctgt gcaatagaaa tttctacaga     7260

tacaggtata ggggctcaag gaggtatgtc ggtcagtagt caaaactatg aaatgatact     7320

ggtttctcca caggaatatg gttccattag gctgggagca aaaacaatgt tttttaagat     7380

tgagaataca tacctgacaa cgatccggaa actgctcctc accactcccg tcatgcctgc     7440

tgtcggcgtt tgaccttcca cgtgacagtt cttcacaatt cctttcatca ttttttaaat     7500

atttttttta ctgcctatgg gctgtgatgt atatagaagt tgtacattaa acataccctc     7560

atttttttct tttctttttt tttttttttt ttagtacaaa gttttagttt ctttttcatg     7620

atgtggtaac tacgaagtga tggtagattt aaataatttt ttatttttat tttatatatt     7680

ttttcattag ggccatatct ccaaaaaaag aaagaaaaaa tacaaaaaac aaaaacaaaa     7740

aaaaaagagg gtaatgtaca agtttctgta tgtataaagt catgctcgat ttcaggagag     7800

cagctgatca caatttgctt catgaatcaa ggtgtggaaa tggttatata tggattgatt     7860

tagaaaatgg ttaccagtac agtcaaaaaa gagaaaatga aaaaaataca actaaaagga     7920

agaaacacaa cttcaaagat ttttcagtga tgagaatcca catttgtatt tcaagataat     7980

gtagtttaaa aaaaaaaaaa agaaaaaaac ttgatgtaaa ttcctccttt tcctctggct     8040

taatgaatat catttattca gtataaaatc tttatatgtt ccacatgtta agaataaatg     8100

tacattaaat cttgttaagc actgtgatgg gtgttcttga atactgttct agtttcctta     8160

aagtggtttc ctagtaatca agttatttac aagaaatagg ggaatgcagc agtgtattca     8220

cattataaaa ccctacattt ggaagagacc tttaggggtt acctacttta gagtggggag     8280

caacagtttg attttctcaa attacttagc taattagtct ttctttgaag caattaactc     8340

taacgacatt gaggtatgat cattttcagt atttatggga ggtggctgct gacccacttg     8400

aggtgagatc tcagaagctt aactggcctg aaaatgtaac attctgcctt ttactaactc     8460

catcttagtt taatcaaagt tcaatctatt ccttgtttct tctgtgtgcc tcagagttat     8520

tttgcattta gtttactcca ccgtgtataa tatttatact gtgcaatgtt aaaaaagaat     8580

ctgttatatt gtatgtggtg tacatagtgc aaagtgatga tttctatttc agggcatatt     8640

atggttctca tattccttcc tacctggtgc acagtagctt tttaatacta gtcacttcta     8700

atttaaactt tctcttcctg ggtcattgac tgttactgtg taataatcga tttctttgaa     8760

actgctgcat aattatgctg ttagtggacc tctacctctt ctcttccctc tcccaatcac     8820

agtatactca gaatccccag cccctcgcat acattgtgtc ggttcacatt actcacagta     8880

atatatggaa gagttagaca agaacatgca gttacagtca ttgtgagacg tgactctcca     8940

gtgtcacgag gaaaaaaatc atcttttctg caaacagtct ctcatctgtc aactcccaca     9000

ttactgagtc aaacagtctt cttacataac aatgcaacca aatatatgtt gaattaaaga     9060

cccatttata attctgcttt aaatacatct gcttgctaag aacagatttc agtgctccaa     9120

gcttcaaata tggagatttg taagagggaa ttcaatatta ttctaatttc tctcttacag     9180

agtacaaata aaaggtgtat acaaactccg aacatatcca gtattccaat tcctttgtca     9240

atcagaagag taaaataatt aacaaaagac tgttgttatg gtttgcattg taaccgatac     9300

gcagagtctg accgttgggc aacaagtttt tctatcctga tgcgcaacac agtctctaga     9360

gactaatcca ggaagacttt agcctccttt ccatattctc acccccgaat caagatttac     9420

agaagcccac gaagaattta cagcctgctt gagatcatct tgcctataaa ctgagttatt     9480

gctttgtcct aaaaattagt cggttttttt ttttctatga ggcttttcag aaatttacag     9540

gatgcccaga ctttacatgt gtaccaaaaa aaaaaaaaag ataaaaaata aaggtgcaaa     9600

gaaagtttag tattttggaa tggtgctata aagttgaaaa aaaaaaaa                  9648


<210>  1459
<211>  2195
<212>  DNA
<213>  homo sapiens

<400>  1459
ttattttgat tcaccgcaga gggcggtcta cgagagcgca gagccccact cggccagcgg       60

ggtctggcgg gggacctgtc gcgctgaaag ctccagggta gggccgacgc ccatcaggct      120

gggcatccgt tcgggatgcg caggttgcga tctgcaaccg gcggcgccac gcccaggcgg      180

gcggagcgcg gttcccggag tctcgcgccc gcggtcatgt gacacagcga agatggcgtc      240

gcccggctgc ctgtggctct tggctgtggc tctcctgcca tggacctgcg cttctcgggc      300

gctgcagcat ctggacccgc cggcgccgct gccgttggtg atctggcatg ggatgggtgt      360

ttttggactc cctcgatgcc caggagagag ctctcacatc tgtgacttca tccgaaaaac      420

actgaatgct ggggcgtact ccaaagttgt tcaggaacgc ctcgtgcaag ccgaatactg      480

gcatgacccc ataaaggagg atgtgtatcg caaccacagc atcttcttgg cagatataaa      540

tcaggagcgg ggtatcaatg agtcctacaa gaaaaacctg atggccctga agaagtttgt      600

gatggtgaaa ttcctcaatg attccattgt ggaccctgta gattcggagt ggtttggatt      660

ttacagaagt ggccaagcca aggaaaccat tcccttacag gagacctccc tgtacacaca      720

ggaccgcctg gggctaaagg aaatggacaa tgcaggacag ctagtgtttc tggctacaga      780

aggggaccat cttcagttgt ctgaagaatg gttttatgcc cacatcatac cattccttgg      840

atgaaacccg tatagttcac aatagagctc agggagcccc taactcttcc aaaccacatg      900

ggagacagtt tccttcatgc ccaagcctga gctcagatcc agcttgcaac taatccttct      960

atcatctaac atgccctact tggaaagatc taagatctga atcttatcct ttgccatctt     1020

ctgttaccat atggtgttga atgcaagttt aattaccatg gagattgttt tacaaacttt     1080

tgatgtggtc aagttcagtt ttagaaaagg gagtctgttc cagatcagtg ccagaactgt     1140

gcccaggccc aaaggagaca actaactaaa gtagtgagat agattctaag ggcaaacatt     1200

tttccaagtc ttgccatatt tcaagcaaag aggtgcccag gcctgaggta ctcacataaa     1260

tgctttgttt tgctggtgat ttaaccagtg cttggaaaaa tcttgcttgg ctatttctgc     1320

atcatttctt aaggctgcct tcctctctca gtacgttgcc ctctgtgcta tcatcttatc     1380

atcaattatt agacaaatcc cactggccta cagtcttgct tctgcagcac ccactttgtc     1440

tcctcaggta gtgatgaatt agttgctgtc acaaaaggag ggaagtagca cccaaattaa     1500

gttgcttaag agaggaaatg tacatcttgt ataacttagg gagcgaagaa aatgtaggcg     1560

cgaaagtgaa aagtgaggca gctagttctt cctattccat tctcgaccaa cctgcccttt     1620

cttaatatga ctagtggtct tgatgctaga gtcaacttac tctgttgctg gctttagcag     1680

agaataggag gaaccatatg aaaaagatca ggctttctga cttccatccc caaaacacat     1740

ttaccagcat actccaaact gtttctgatg tgttccatga gaaaaggatt gtttgctcaa     1800

aaagcttgga aaatactaca cactcccttt ctccttctgg agatcaaccc acattagagt     1860

gtctaaggac tcctgagaat tcctgttaca gtaaacaaaa ctaacgtaat ctaccatttc     1920

ctacactatt tgagcatgga aatcatagtc cccactctgt gaaaacttaa cgctttttgg     1980

aagacatttc tgtagcatgt cagtttggag aaatgatgag ctacgccttg atgaaagaac     2040

cgtgttggtg ctgctaagtt tagccattat ggtttttcct ttctctctct taagccttat     2100

tcttcaacta aaagatgagg attaagagca agaagttggg ggggatgtga aaataatttt     2160

atgaggttgt ctaaaataaa gagtagtttc ttatc                                2195


<210>  1460
<211>  3748
<212>  DNA
<213>  homo sapiens

<400>  1460
ggctgaggcg gaggagccgc cgcttctgac ctcgctctgg ctccggtgcg cgcggctgag       60

cgcgtgcgag gccccgcgcg tcgggcaggg gcggcggcgg ccactgcgcg ccgccctgag      120

gagcgcccca gcggcggcgc gactgcggct gaggagagag ccggctccgg gcctccgcgt      180

cctcctgctc ccccggcccc ccgcctcctc gggggggcgg cggcggcgat gttctcggtc      240

ctctcgtacg ggcggctggt ggcccgcgcc gtgctcggcg gcctctcgca gaccgacccc      300

agggccggcg gcggcggcgg cggcgactac ggactggtga cggccggctg cggcttcggg      360

aaggacttcc gtaagggcct cctcaagaag ggcgcgtgct acggggacga cgcgtgcttc      420

gtggcccggc accgttccgc ggacgtgctc ggggttgcag atggtgtagg aggctggaga      480

gactatggag ttgatccatc tcaattctca gggactttaa tgcggacgtg tgaacgttta      540

gtaaaagaag gacggttcgt acctagtaat cccattggaa ttctcaccac aagctactgt      600

gagttgctgc aaaataaagt ccctttgctc ggtagcagca ccgcctgcat tgtggtgctg      660

gacagaacca gccaccgctt acacacagca aacctgggcg attcaggctt cctggttgtc      720

aggggtggtg aagtcgtgca ccgatcagat gagcagcagc attacttcaa cactccattc      780

cagctctcaa tcgctccccc tgaagccgag ggagtcgtct tgagcgacag tccggatgct      840

gctgatagca cgtctttcga tgtccagcta ggagacatta tcctgacggc aacagatgga      900

ctctttgaca acatgcctga ttatatgatt cttcaggagc taaaaaagtt aaagaattca      960

aattatgaga gtatacaaca gactgccaga agcattgctg agcaagctca tgagctggcc     1020

tatgacccaa attatatgtc accttttgca cagtttgcat gtgacaatgg attgaatgtg     1080

agaggtggaa agccagatga catcaccgtc cttctttcaa tagtggctga gtatacagac     1140

tagctgaggt gtcaagtcct gcctttcctt tcatcatccc aaatttcccc tgccatgtgt     1200

gctgatcctg ctggcaggac cacatttctt tgccactgat ctcaatggcc agtgatgtaa     1260

gtcttttgcc tgtcttcttg agactcgttg agatctttgt tgagaaccac tactatcatt     1320

cactagctca tatctgccgg cagcaattga agagatccaa tatttgaaga ttggccttca     1380

tttctcgatg ttctttccat gatggggatg gaggtgttca gtgccaccgt ggctgttact     1440

tttcaaagta gttgaagtat tgaaaatgag taatgttggt aaagtgaatt caaaatccta     1500

gtatgctaaa gggatggtac aagtctaaca caaattgtac gtaatgatac atctactaga     1560

aacatacatt attcatcaaa agaaatgtta catgtgtact ccacaggcat agtctttgtt     1620

atgatgattg gtgtggcttt atgtctttgt tataaactcc tatttttcag gggcttatga     1680

ttctgctcta aaacattgct ctgggttata cagttttgat cccaaaagct tttttgttac     1740

aaatcgggag aaaaatccat tttagttcta tggatggaaa tatttcatgc ttttaaaaag     1800

atgtttgtgt tcctgtggtt aaagttttgg cagtttattg attagtccaa atcacaggct     1860

aaggcctgat ctccaggagg ggtaggggag acactttacc agtatttttt tatggaaata     1920

atactcaagg ttgtaaaacc cctcaaagcc tagaaattta attgttatgg ctgaaattcc     1980

tcctagttgt ctgatagaat gcccctgaat gggaactcta ggtcccaagg cctgaagggt     2040

tgagaacaga cagctgtaac tttgaatttt gttggctttc agtggtcatg ctacctaccc     2100

atactcgtac tctcagacct tttattagta gccttgcttt ctatagagca tgcaccaaat     2160

ccagtgagtc catgtggaga gagcactgtg tgcgcagcgg cagcagcaca gacgtccatg     2220

aggaaaactc ccagtgatga tctgacattt acaattaccc cacatggaaa tttaggggtt     2280

tctgaatcaa gcttaatgtt tacagtttcc aaatagccat tttgcagtgt atagtttcct     2340

tacaaaacta ccccgcattc agttttcaca ttatctgcaa gctgaaactt atttttaagt     2400

tttgtgtaca agttgactgc tgtaaagata tatatttttg ggtcagtttt tttccttcat     2460

taacttggtg gtagaaaaaa atatatactt agaaatcctt aaattaaagc catgttttat     2520

atataagtca ggtaacattg gtgtatagat gagaatgcaa ttaaacctga tgagaatcta     2580

cttgagaata tagaaagtct ttctctaaag gagatactga ctccctggtt tattgcatta     2640

aaatttatgt ttgaggttac ctcaacttgt tttaaaagat tttgttttgt gaatttgtac     2700

tgtatatttg agtaactgtc aggcttttat ttaaaattgt ttaacatgta ccatgtacat     2760

gtcattacta tatttcaatg catcatgctt gtaacaggca tttcatttat aataagaatg     2820

agttattcat ttgtaagccg ttcagtaatt tatctactat tcctaaattg gcataatgtt     2880

agataatcta ttttgaatca cctttaatta catgtcagaa tgccttaact accctaactt     2940

gacaaaacag aattctttgg tagacgcggt gggggcgggg tggggggtct ggacggagtc     3000

tctatttaag gagaaatcat catgctatga taaaacacag aagcatgagt ggcaagtggc     3060

ggggtattta ttttgcacaa actatttgca gtctctgtgt atttaaaaag taaagaaagt     3120

tgcatccaga agggttttgt tagaatgaat acatttatat taggactgac aacttcagct     3180

cttttgttta ggttttcaat tatttttggt aagagtatgt agccttatga tctggatata     3240

ttttgcattc attttccaac gcctacattt aattcctggt aagagcagtg ctcgtcaagt     3300

ttctggtttt tctctgctct catttaaccc gtcaaacaca atctttgtaa agctagattg     3360

gtggtgtttt atacaactta tttactcagc ttaccttttt gagaaacgat tgttagaaat     3420

tgacgatgtg tttgttccag tgatactgaa agtagtgggg gcaagaattg agtttcacag     3480

tggaattggc tttggatctg gcctatagat tagtgacata aaatattttc tctattttcc     3540

cctgttcttt ttgtgttatg cacttaattt tatgactgcc gggggggtca gctggagtgc     3600

tgcttaacaa gtatctctcc tactctcagt ggtcagaggc tgtgttggac ccatagtaga     3660

attttccagg tcacagaccc aagcttccat gggttgttac tgtgctgtac cacttggtgg     3720

gtctgattct gaacctgatg tgtgtgtt                                        3748


<210>  1461
<211>  3748
<212>  DNA
<213>  homo sapiens

<400>  1461
ggctgaggcg gaggagccgc cgcttctgac ctcgctctgg ctccggtgcg cgcggctgag       60

cgcgtgcgag gccccgcgcg tcgggcaggg gcggcggcgg ccactgcgcg ccgccctgag      120

gagcgcccca gcggcggcgc gactgcggct gaggagagag ccggctccgg gcctccgcgt      180

cctcctgctc ccccggcccc ccgcctcctc gggggggcgg cggcggcgat gttctcggtc      240

ctctcgtacg ggcggctggt ggcccgcgcc gtgctcggcg gcctctcgca gaccgacccc      300

agggccggcg gcggcggcgg cggcgactac ggactggtga cggccggctg cggcttcggg      360

aaggacttcc gtaagggcct cctcaagaag ggcgcgtgct acggggacga cgcgtgcttc      420

gtggcccggc accgttccgc ggacgtgctc ggggttgcag atggtgtagg aggctggaga      480

gactatggag ttgatccatc tcaattctca gggactttaa tgcggacgtg tgaacgttta      540

gtaaaagaag gacggttcgt acctagtaat cccattggaa ttctcaccac aagctactgt      600

gagttgctgc aaaataaagt ccctttgctc ggtagcagca ccgcctgcat tgtggtgctg      660

gacagaacca gccaccgctt acacacagca aacctgggcg attcaggctt cctggttgtc      720

aggggtggtg aagtcgtgca ccgatcagat gagcagcagc attacttcaa cactccattc      780

cagctctcaa tcgctccccc tgaagccgag ggagtcgtct tgagcgacag tccggatgct      840

gctgatagca cgtctttcga tgtccagcta ggagacatta tcctgacggc aacagatgga      900

ctctttgaca acatgcctga ttatatgatt cttcaggagc taaaaaagtt aaagaattca      960

aattatgaga gtatacaaca gactgccaga agcattgctg agcaagctca tgagctggcc     1020

tatgacccaa attatatgtc accttttgca cagtttgcat gtgacaatgg attgaatgtg     1080

agaggtggaa agccagatga catcaccgtc cttctttcaa tagtggctga gtatacagac     1140

tagctgaggt gtcaagtcct gcctttcctt tcatcatccc aaatttcccc tgccatgtgt     1200

gctgatcctg ctggcaggac cacatttctt tgccactgat ctcaatggcc agtgatgtaa     1260

gtcttttgcc tgtcttcttg agactcgttg agatctttgt tgagaaccac tactatcatt     1320

cactagctca tatctgccgg cagcaattga agagatccaa tatttgaaga ttggccttca     1380

tttctcgatg ttctttccat gatggggatg gaggtgttca gtgccaccgt ggctgttact     1440

tttcaaagta gttgaagtat tgaaaatgag taatgttggt aaagtgaatt caaaatccta     1500

gtatgctaaa gggatggtac aagtctaaca caaattgtac gtaatgatac atctactaga     1560

aacatacatt attcatcaaa agaaatgtta catgtgtact ccacaggcat agtctttgtt     1620

atgatgattg gtgtggcttt atgtctttgt tataaactcc tatttttcag gggcttatga     1680

ttctgctcta aaacattgct ctgggttata cagttttgat cccaaaagct tttttgttac     1740

aaatcgggag aaaaatccat tttagttcta tggatggaaa tatttcatgc ttttaaaaag     1800

atgtttgtgt tcctgtggtt aaagttttgg cagtttattg attagtccaa atcacaggct     1860

aaggcctgat ctccaggagg ggtaggggag acactttacc agtatttttt tatggaaata     1920

atactcaagg ttgtaaaacc cctcaaagcc tagaaattta attgttatgg ctgaaattcc     1980

tcctagttgt ctgatagaat gcccctgaat gggaactcta ggtcccaagg cctgaagggt     2040

tgagaacaga cagctgtaac tttgaatttt gttggctttc agtggtcatg ctacctaccc     2100

atactcgtac tctcagacct tttattagta gccttgcttt ctatagagca tgcaccaaat     2160

ccagtgagtc catgtggaga gagcactgtg tgcgcagcgg cagcagcaca gacgtccatg     2220

aggaaaactc ccagtgatga tctgacattt acaattaccc cacatggaaa tttaggggtt     2280

tctgaatcaa gcttaatgtt tacagtttcc aaatagccat tttgcagtgt atagtttcct     2340

tacaaaacta ccccgcattc agttttcaca ttatctgcaa gctgaaactt atttttaagt     2400

tttgtgtaca agttgactgc tgtaaagata tatatttttg ggtcagtttt tttccttcat     2460

taacttggtg gtagaaaaaa atatatactt agaaatcctt aaattaaagc catgttttat     2520

atataagtca ggtaacattg gtgtatagat gagaatgcaa ttaaacctga tgagaatcta     2580

cttgagaata tagaaagtct ttctctaaag gagatactga ctccctggtt tattgcatta     2640

aaatttatgt ttgaggttac ctcaacttgt tttaaaagat tttgttttgt gaatttgtac     2700

tgtatatttg agtaactgtc aggcttttat ttaaaattgt ttaacatgta ccatgtacat     2760

gtcattacta tatttcaatg catcatgctt gtaacaggca tttcatttat aataagaatg     2820

agttattcat ttgtaagccg ttcagtaatt tatctactat tcctaaattg gcataatgtt     2880

agataatcta ttttgaatca cctttaatta catgtcagaa tgccttaact accctaactt     2940

gacaaaacag aattctttgg tagacgcggt gggggcgggg tggggggtct ggacggagtc     3000

tctatttaag gagaaatcat catgctatga taaaacacag aagcatgagt ggcaagtggc     3060

ggggtattta ttttgcacaa actatttgca gtctctgtgt atttaaaaag taaagaaagt     3120

tgcatccaga agggttttgt tagaatgaat acatttatat taggactgac aacttcagct     3180

cttttgttta ggttttcaat tatttttggt aagagtatgt agccttatga tctggatata     3240

ttttgcattc attttccaac gcctacattt aattcctggt aagagcagtg ctcgtcaagt     3300

ttctggtttt tctctgctct catttaaccc gtcaaacaca atctttgtaa agctagattg     3360

gtggtgtttt atacaactta tttactcagc ttaccttttt gagaaacgat tgttagaaat     3420

tgacgatgtg tttgttccag tgatactgaa agtagtgggg gcaagaattg agtttcacag     3480

tggaattggc tttggatctg gcctatagat tagtgacata aaatattttc tctattttcc     3540

cctgttcttt ttgtgttatg cacttaattt tatgactgcc gggggggtca gctggagtgc     3600

tgcttaacaa gtatctctcc tactctcagt ggtcagaggc tgtgttggac ccatagtaga     3660

attttccagg tcacagaccc aagcttccat gggttgttac tgtgctgtac cacttggtgg     3720

gtctgattct gaacctgatg tgtgtgtt                                        3748


<210>  1462
<211>  2161
<212>  DNA
<213>  homo sapiens

<400>  1462
ggaggagctg ttttgcggcg ggcggagctg caggctgggc agggcttagc ctgtgcgctt       60

ctgctggcct ccttttcgcc ctcccacccg cactgcagtc tccagcctga gccatgggcc      120

gccgagccct cctgctcctg cttctgtctt ttctggcgcc ctgggccacc atagccctcc      180

ggccggcctt aagggccctc ggcagcctac acttgccaac caaccccaca tccctcccgg      240

ctgtagccaa gaactattcg gttctctact tccaacagaa ggttgatcat tttggattta      300

atactgtgaa aacttttaat cagcggtacc tagtagctga taaatactgg aagaaaaatg      360

gtggatcaat acttttctac actggtaatg aaggggacat tatctggttt tgtaataaca      420

cggggttcat gtgggatgtg gctgaggaac tgaaagctat gttggtgttt gctgaacatc      480

gatactatgg agagtctctc ccctttggtg acaactcatt caaggattcc agacacttga      540

atttcctgac atcagaacaa gctctggctg attttgcaga gttaatcaaa cacttgaaaa      600

gaacaatccc aggagctgaa aatcaacctg tcattgccat aggaggctcc tatggtggca      660

tgcttgccgc ctggtttagg atgaaatatc ctcatatggt agttggagct cttgcagctt      720

ctgcccctat ctggcagttt gaggatttag taccttgtgg tgtatttatg aagatcgtaa      780

ctacagattt taggaaaagc ggtccacatt gttcagagag catccacagg tcctgggatg      840

ccattaatcg actctcaaat actggcagtg gtttgcagtg gcttactgga gcccttcact      900

tatgcagccc attaacttct caggacatcc aacatttgaa agactggatc tctgaaacct      960

gggtgaatct ggcaatggtg gactatcctt atgcctctaa ctttttacag cctttgcctg     1020

cttggcctat caaggtagtg tgccagtatt tgaaaaatcc caatgtatct gattcactgc     1080

tgctgcagaa tattttccaa gctctgaatg tatattacaa ttattcgggc caggtgaaat     1140

gcctgaatat ttcagagaca gcaactagca gtctgggaac actgggttgg agctatcagg     1200

cctgcacaga agtagtcatg cccttttgta ctaatggtgt cgatgacatg tttgaacctc     1260

actcatggaa cttaaaggaa ctttctgatg actgttttca acagtggggt gtgagaccaa     1320

ggccctcctg gatcactact atgtatggag gcaaaaacat tagttcacac acaaacattg     1380

ttttcagcaa tggtgaacta gacccctggt caggaggtgg agtaactaag gatatcacag     1440

acactctggt tgcagtcacc atctcagagg gggcccacca cttagatctc cgcaccaaga     1500

atgccttgga tcctatgtct gtgctgttag cccgctcctt ggaagttaga catatgaaga     1560

attggatcag agatttctat gacagtgcgg gaaagcagca ctgagaaact tttgattgtt     1620

ttcaatttct tcttttatgt tcacaccacc acattcccat tcactttgat tttctacatg     1680

taattacctt cttttgttta tcattagatt tgatggggcc aaagttgaga tagaatagag     1740

ggtgatgacg gtaagagcaa gtgtcccatg aatgtgattt cctgggttct cactgtcttt     1800

gcaccacgtc taggaagaat cttcttgata gctctcccac accatcagtg gccctcataa     1860

ctggagtaga gttcctggtt gcttttcata agagggagag ttactttctt tgtatctctg     1920

caagcagaga tttctctttg gttttgaggt tgaagtgtct ttggcccatt tgtaagtccc     1980

catccctacc ctacacaaag taaaagcaga agatagataa aaaatgatgt aattgcagct     2040

ggtaggatgt ctggtgccaa tccaggaagt gagagccatt tcttttgtac cggatttaat     2100

gactttgaac tgtgctgtaa ataaataata cagctggacc ttaaaaaaaa aaaaaaaaaa     2160

a                                                                     2161


<210>  1463
<211>  2224
<212>  DNA
<213>  homo sapiens

<400>  1463
ggaggagctg ttttgcggcg ggcggagctg caggctgggc agggcttagc ctgtgcgctt       60

ctgctggcct ccttttcgcc ctcccacccg cactgcagtc tccagcctga gccatgggcc      120

gccgagccct cctgctcctg cttctgtctt ttctggcgcc ctgggccacc atagccctcc      180

ggccggcctt aagggccctc ggcagcctac acttgccaac caaccccaca tccctcccgg      240

ctgtagccaa gaactattcg gttctctact tccaacagaa ggcccttgct gctgggcagt      300

tgcacatatg tattatccaa ctaaatcatt acaagactcc tctggttgat cattttggat      360

ttaatactgt gaaaactttt aatcagcggt acctagtagc tgataaatac tggaagaaaa      420

atggtggatc aatacttttc tacactggta atgaagggga cattatctgg ttttgtaata      480

acacggggtt catgtgggat gtggctgagg aactgaaagc tatgttggtg tttgctgaac      540

atcgatacta tggagagtct ctcccctttg gtgacaactc attcaaggat tccagacact      600

tgaatttcct gacatcagaa caagctctgg ctgattttgc agagttaatc aaacacttga      660

aaagaacaat cccaggagct gaaaatcaac ctgtcattgc cataggaggc tcctatggtg      720

gcatgcttgc cgcctggttt aggatgaaat atcctcatat ggtagttgga gctcttgcag      780

cttctgcccc tatctggcag tttgaggatt tagtaccttg tggtgtattt atgaagatcg      840

taactacaga ttttaggaaa agcggtccac attgttcaga gagcatccac aggtcctggg      900

atgccattaa tcgactctca aatactggca gtggtttgca gtggcttact ggagcccttc      960

acttatgcag cccattaact tctcaggaca tccaacattt gaaagactgg atctctgaaa     1020

cctgggtgaa tctggcaatg gtggactatc cttatgcctc taacttttta cagcctttgc     1080

ctgcttggcc tatcaaggta gtgtgccagt atttgaaaaa tcccaatgta tctgattcac     1140

tgctgctgca gaatattttc caagctctga atgtatatta caattattcg ggccaggtga     1200

aatgcctgaa tatttcagag acagcaacta gcagtctggg aacactgggt tggagctatc     1260

aggcctgcac agaagtagtc atgccctttt gtactaatgg tgtcgatgac atgtttgaac     1320

ctcactcatg gaacttaaag gaactttctg atgactgttt tcaacagtgg ggtgtgagac     1380

caaggccctc ctggatcact actatgtatg gaggcaaaaa cattagttca cacacaaaca     1440

ttgttttcag caatggtgaa ctagacccct ggtcaggagg tggagtaact aaggatatca     1500

cagacactct ggttgcagtc accatctcag agggggccca ccacttagat ctccgcacca     1560

agaatgcctt ggatcctatg tctgtgctgt tagcccgctc cttggaagtt agacatatga     1620

agaattggat cagagatttc tatgacagtg cgggaaagca gcactgagaa acttttgatt     1680

gttttcaatt tcttctttta tgttcacacc accacattcc cattcacttt gattttctac     1740

atgtaattac cttcttttgt ttatcattag atttgatggg gccaaagttg agatagaata     1800

gagggtgatg acggtaagag caagtgtccc atgaatgtga tttcctgggt tctcactgtc     1860

tttgcaccac gtctaggaag aatcttcttg atagctctcc cacaccatca gtggccctca     1920

taactggagt agagttcctg gttgcttttc ataagaggga gagttacttt ctttgtatct     1980

ctgcaagcag agatttctct ttggttttga ggttgaagtg tctttggccc atttgtaagt     2040

ccccatccct accctacaca aagtaaaagc agaagataga taaaaaatga tgtaattgca     2100

gctggtagga tgtctggtgc caatccagga agtgagagcc atttcttttg taccggattt     2160

aatgactttg aactgtgctg taaataaata atacagctgg accttaaaaa aaaaaaaaaa     2220

aaaa                                                                  2224


<210>  1464
<211>  2161
<212>  DNA
<213>  homo sapiens

<400>  1464
ggaggagctg ttttgcggcg ggcggagctg caggctgggc agggcttagc ctgtgcgctt       60

ctgctggcct ccttttcgcc ctcccacccg cactgcagtc tccagcctga gccatgggcc      120

gccgagccct cctgctcctg cttctgtctt ttctggcgcc ctgggccacc atagccctcc      180

ggccggcctt aagggccctc ggcagcctac acttgccaac caaccccaca tccctcccgg      240

ctgtagccaa gaactattcg gttctctact tccaacagaa ggttgatcat tttggattta      300

atactgtgaa aacttttaat cagcggtacc tagtagctga taaatactgg aagaaaaatg      360

gtggatcaat acttttctac actggtaatg aaggggacat tatctggttt tgtaataaca      420

cggggttcat gtgggatgtg gctgaggaac tgaaagctat gttggtgttt gctgaacatc      480

gatactatgg agagtctctc ccctttggtg acaactcatt caaggattcc agacacttga      540

atttcctgac atcagaacaa gctctggctg attttgcaga gttaatcaaa cacttgaaaa      600

gaacaatccc aggagctgaa aatcaacctg tcattgccat aggaggctcc tatggtggca      660

tgcttgccgc ctggtttagg atgaaatatc ctcatatggt agttggagct cttgcagctt      720

ctgcccctat ctggcagttt gaggatttag taccttgtgg tgtatttatg aagatcgtaa      780

ctacagattt taggaaaagc ggtccacatt gttcagagag catccacagg tcctgggatg      840

ccattaatcg actctcaaat actggcagtg gtttgcagtg gcttactgga gcccttcact      900

tatgcagccc attaacttct caggacatcc aacatttgaa agactggatc tctgaaacct      960

gggtgaatct ggcaatggtg gactatcctt atgcctctaa ctttttacag cctttgcctg     1020

cttggcctat caaggtagtg tgccagtatt tgaaaaatcc caatgtatct gattcactgc     1080

tgctgcagaa tattttccaa gctctgaatg tatattacaa ttattcgggc caggtgaaat     1140

gcctgaatat ttcagagaca gcaactagca gtctgggaac actgggttgg agctatcagg     1200

cctgcacaga agtagtcatg cccttttgta ctaatggtgt cgatgacatg tttgaacctc     1260

actcatggaa cttaaaggaa ctttctgatg actgttttca acagtggggt gtgagaccaa     1320

ggccctcctg gatcactact atgtatggag gcaaaaacat tagttcacac acaaacattg     1380

ttttcagcaa tggtgaacta gacccctggt caggaggtgg agtaactaag gatatcacag     1440

acactctggt tgcagtcacc atctcagagg gggcccacca cttagatctc cgcaccaaga     1500

atgccttgga tcctatgtct gtgctgttag cccgctcctt ggaagttaga catatgaaga     1560

attggatcag agatttctat gacagtgcgg gaaagcagca ctgagaaact tttgattgtt     1620

ttcaatttct tcttttatgt tcacaccacc acattcccat tcactttgat tttctacatg     1680

taattacctt cttttgttta tcattagatt tgatggggcc aaagttgaga tagaatagag     1740

ggtgatgacg gtaagagcaa gtgtcccatg aatgtgattt cctgggttct cactgtcttt     1800

gcaccacgtc taggaagaat cttcttgata gctctcccac accatcagtg gccctcataa     1860

ctggagtaga gttcctggtt gcttttcata agagggagag ttactttctt tgtatctctg     1920

caagcagaga tttctctttg gttttgaggt tgaagtgtct ttggcccatt tgtaagtccc     1980

catccctacc ctacacaaag taaaagcaga agatagataa aaaatgatgt aattgcagct     2040

ggtaggatgt ctggtgccaa tccaggaagt gagagccatt tcttttgtac cggatttaat     2100

gactttgaac tgtgctgtaa ataaataata cagctggacc ttaaaaaaaa aaaaaaaaaa     2160

a                                                                     2161


<210>  1465
<211>  2224
<212>  DNA
<213>  homo sapiens

<400>  1465
ggaggagctg ttttgcggcg ggcggagctg caggctgggc agggcttagc ctgtgcgctt       60

ctgctggcct ccttttcgcc ctcccacccg cactgcagtc tccagcctga gccatgggcc      120

gccgagccct cctgctcctg cttctgtctt ttctggcgcc ctgggccacc atagccctcc      180

ggccggcctt aagggccctc ggcagcctac acttgccaac caaccccaca tccctcccgg      240

ctgtagccaa gaactattcg gttctctact tccaacagaa ggcccttgct gctgggcagt      300

tgcacatatg tattatccaa ctaaatcatt acaagactcc tctggttgat cattttggat      360

ttaatactgt gaaaactttt aatcagcggt acctagtagc tgataaatac tggaagaaaa      420

atggtggatc aatacttttc tacactggta atgaagggga cattatctgg ttttgtaata      480

acacggggtt catgtgggat gtggctgagg aactgaaagc tatgttggtg tttgctgaac      540

atcgatacta tggagagtct ctcccctttg gtgacaactc attcaaggat tccagacact      600

tgaatttcct gacatcagaa caagctctgg ctgattttgc agagttaatc aaacacttga      660

aaagaacaat cccaggagct gaaaatcaac ctgtcattgc cataggaggc tcctatggtg      720

gcatgcttgc cgcctggttt aggatgaaat atcctcatat ggtagttgga gctcttgcag      780

cttctgcccc tatctggcag tttgaggatt tagtaccttg tggtgtattt atgaagatcg      840

taactacaga ttttaggaaa agcggtccac attgttcaga gagcatccac aggtcctggg      900

atgccattaa tcgactctca aatactggca gtggtttgca gtggcttact ggagcccttc      960

acttatgcag cccattaact tctcaggaca tccaacattt gaaagactgg atctctgaaa     1020

cctgggtgaa tctggcaatg gtggactatc cttatgcctc taacttttta cagcctttgc     1080

ctgcttggcc tatcaaggta gtgtgccagt atttgaaaaa tcccaatgta tctgattcac     1140

tgctgctgca gaatattttc caagctctga atgtatatta caattattcg ggccaggtga     1200

aatgcctgaa tatttcagag acagcaacta gcagtctggg aacactgggt tggagctatc     1260

aggcctgcac agaagtagtc atgccctttt gtactaatgg tgtcgatgac atgtttgaac     1320

ctcactcatg gaacttaaag gaactttctg atgactgttt tcaacagtgg ggtgtgagac     1380

caaggccctc ctggatcact actatgtatg gaggcaaaaa cattagttca cacacaaaca     1440

ttgttttcag caatggtgaa ctagacccct ggtcaggagg tggagtaact aaggatatca     1500

cagacactct ggttgcagtc accatctcag agggggccca ccacttagat ctccgcacca     1560

agaatgcctt ggatcctatg tctgtgctgt tagcccgctc cttggaagtt agacatatga     1620

agaattggat cagagatttc tatgacagtg cgggaaagca gcactgagaa acttttgatt     1680

gttttcaatt tcttctttta tgttcacacc accacattcc cattcacttt gattttctac     1740

atgtaattac cttcttttgt ttatcattag atttgatggg gccaaagttg agatagaata     1800

gagggtgatg acggtaagag caagtgtccc atgaatgtga tttcctgggt tctcactgtc     1860

tttgcaccac gtctaggaag aatcttcttg atagctctcc cacaccatca gtggccctca     1920

taactggagt agagttcctg gttgcttttc ataagaggga gagttacttt ctttgtatct     1980

ctgcaagcag agatttctct ttggttttga ggttgaagtg tctttggccc atttgtaagt     2040

ccccatccct accctacaca aagtaaaagc agaagataga taaaaaatga tgtaattgca     2100

gctggtagga tgtctggtgc caatccagga agtgagagcc atttcttttg taccggattt     2160

aatgactttg aactgtgctg taaataaata atacagctgg accttaaaaa aaaaaaaaaa     2220

aaaa                                                                  2224


<210>  1466
<211>  4225
<212>  DNA
<213>  homo sapiens

<400>  1466
gcagagggtg cggcccagag gaggccgcgg gccgggaagg gccgggcggg acgggaaacg       60

ttagggcagc ggcccccggg gtgagggggc cgagcggacg ggcagggccc cgaggcgaac      120

tctgcccgga tgaggaacaa agcagtgggg caggcgcgtg cgcccccagc gcagctggca      180

ggttgggcag cccccttccc gaagcttctg gacggaaggc cccaggtgtt ccccgagatg      240

ccccaacccg tggcggggtg cacggccacc ggccctcggg agaagttggg cggccccggg      300

cgaccccggg gacgagtggc cgcgtcggtg cagcggttgt gagcaagatg tggtagcacg      360

tgaccctgga acgcaaaccc tgatgcctgt tccccaccac ccgagcgctc ctttctctga      420

tatttggccc caagccgatg catcacagga tgaatgaaat gaacctgagt ccagtgggga      480

tggagcagct gacttcatcc tctgtgagca atgccttgcc agtctcagga agtcacctgg      540

gattggctgc ctcacccact cacagtgcca tccctgcccc aggcctccca gtggcaattc      600

caaacctggg tccctccctg agctctctgc cttctgctct gtctttaatg ctaccaatgg      660

gtattgggga tcgaggggtg atgtgtgggt tacctgaaag aaactacacc ctacctccac      720

caccttaccc tcacctggag agcagttatt tcagaaccat tctacctggc attttatctt      780

atttagctga cagaccacct ccacagtaca tccaccctaa ctctataaat gttgatggta      840

atacagcatt atctatcacc aataaccctt cagcactaga tccctatcag tccaatggaa      900

atgttggatt agaaccaggc attgtttcaa tagactctcg ctctgtgaac acacatggtg      960

cccaaagtct tcatcccagt gatggccatg aggtggcctt ggacacagca atcactatgg     1020

agaacgtttc tagggttacc agcccaattt cgacagatgg aatggcagag gagcttacga     1080

tggacggtgt tgcaggcgag cattcccaaa tcccaaatgg ctccagaagt catgaacctc     1140

tgtctgtgga ttctgtgagc aacaaccttg cagcagacgc tgtaggacat ggtggtgtga     1200

tacccatgca tgggaatggc ctggagctcc ctgtggtcat ggagacagac cacattgcaa     1260

gtcgggtcaa tggcatgtct gacagtgccc tcagtgactc cattcacact gtggccatga     1320

gcaccaactc tgtaagcgtg gcactctcta cctcacacaa ccttgcctcc ctagaatctg     1380

tttccctcca tgaagttggc ctcagcctag aacctgtggc tgtctcctcc atcacccagg     1440

aggttgctat ggggacaggt catgtagatg tatcttcaga cagtctttct tttgtatcac     1500

cttcactgca aatggaagac tccaattcaa acaaggagaa catggcaacc ttgtttacaa     1560

tttggtgtac tctgtgtgac cgcgcctatc cctcggactg tcccgaacat ggaccagtga     1620

cttttgttcc tgacactcca atagagagca gagcaaggct ttctctccca aagcagcttg     1680

ttctccgtca gtcaattgtg ggagcagaag ttggtgtatg gactggagaa accattcctg     1740

tgcggacttg ctttggacct ctaattggcc agcagagtca ctccatggaa gtagcagaat     1800

ggacagacaa ggcagttaac catatctgga agatatacca caatggtgtc ctagaattct     1860

gcatcattac aactgatgaa aatgaatgta attggatgat gtttgtgcgc aaagccagga     1920

accgggaaga gcagaatttg gtggcttatc ctcatgatgg aaaaatcttt ttctgcacct     1980

cacaagatat ccctcctgaa aatgaactgc ttttttatta tagccgagat tatgctcaac     2040

agattggtgt tcctgaacac ccagatgtgc atctctgtaa ctgtggcaag gagtgcaatt     2100

cttacacaga gttcaaagcc catctgacca gccacatcca taaccatctt cctacccagg     2160

gacatagcgg cagccatggg ccaagtcaca gcaaagaaag gaagtggaag tgctcaatgt     2220

gcccccaagc ttttatctct ccttccaaac ttcatgtcca ctttatgggt cacatgggta     2280

tgaagcccca caagtgtgat ttctgtagca aggcttttag tgatcccagc aacctgcgga     2340

cccacctcaa gatacataca ggtcagaaga actacaggtg taccttgtgt gacaagtctt     2400

tcacccagaa ggctcacctg gagtcccaca tggttatcca cactggggag aagaatctta     2460

agtgtgatta ctgtgacaag ttgtttatgc ggaggcagga cctcaagcag cacgtgctca     2520

tccacactca agaacgccag atcaagtgtc ccaagtgtga taagctgttc ttgagaacaa     2580

atcacttaaa gaagcatctc aattctcatg aaggaaaacg ggattatgtc tgtgaaaaat     2640

gtacaaaggc ttatctaacc aaataccatc tcacccgcca cctgaaaacc tgcaaagggc     2700

ccacctccag ttcgtcagca ccagaggagg aagaagagga tgactcagaa gaggaagatc     2760

tagcagactc tgtggggaca gaagactgta ggattaacag tgctgtgtat tcagcggatg     2820

agtctctttc tgcacataaa taaaaggaaa agaaacaagc aattttggat gaaaatgcaa     2880

atggaaaaat acacataacc agttatctac tataatggtt tttatataaa atggttcctg     2940

atttattttc agccagtaat caaaacagac tgggaatgaa taaagcactt acagaagagt     3000

atcctaatga aaacacttta aaacagattg ggaaaactga gcatgtgtcc tgttttaagt     3060

ggtggactgg gagggaagtg tcaacttctg aggtctttat ttacatgata atctgggaga     3120

tgcatttatg cctgaatcaa agctgccttc tgctcaaaca aatcagattt atttcacatt     3180

cttccattat tccattttcc tgctggtcct gtgacttggt aacattctaa acggtccttg     3240

ccccatagcc atcctgattg ctgatagtgt tttatgcaga ctcttgtgac ttatactcac     3300

cacagaatgg attgggacac agcagcataa gtgtgctact tggcagctag taagtttaaa     3360

gcaggacctg ccttaactgc tcctggccac ttggaagttt agggtagatc ttgttttcca     3420

aagtttcggc aggtgcctgg agggcaaata aaaaagcagc agtcagtcag tagtcagtga     3480

tggagagaac aagaggagag atgcctggcc tctgcccaag aaattagctt tgatggaagc     3540

ctgagcaagt cacctggtta ttgtaacgtg gagatctttg taggtttaga catggctccc     3600

tgtctccagt aaacatccag ccattcagac aaagggggcc tggagataca gagagcccaa     3660

ataatgcctg ctggattgtc tcctgatgag tacatgtgga ctcacctgag gaagggaagg     3720

aagggaataa tcttttatgt ttcatttacc ttatgaaaag tgttaaaaca ttgccaactc     3780

aaaataacat tatttaatgc atgtgcaaag ttaggtcttc ccagttgtct cagtgctgag     3840

gaacctcatc agagaagcat ggaagatgcc aaaggatttt tggaaggtaa agaaggctga     3900

atagtgacca catgggcctg ttttcagggt cccagcttag ttaagtcacc catgcacctg     3960

gtcattgtgt ctcccatgca catccagcgt ttctcagaag cagacccacc cttaagttga     4020

caggattgat ggaacatgct ctcctgctca aggcacaacc tctgggctgg agtagaggac     4080

tctggtggga aggttttgct gctaatgtat ttatggaatg aatgtatttc attcaaatct     4140

gtattcctct aggaaggatt aaaattaaac ttttttaaaa tacaggaaaa aaaaaaaaaa     4200

aaaaaaaaaa aaaaaaaaaa aaaaa                                           4225


<210>  1467
<211>  2445
<212>  DNA
<213>  homo sapiens

<400>  1467
aaagcagcca atgggagagc cgaggcgggg aggtgcggcc aatggcgcgg gcctgtttga       60

ttcaaaggtt gcctataaag cgggactgca cgccggtttt tgtccgaggg ctgtcgagtc      120

cgagcgccgc catggctctg ctgtccgagg gcctggacga ggtgcccgcc gcctgcctgt      180

cgccgtgcgg gccgcccaac ccgaccgagc tgttcagcga gtcacggcgc ctggctctgg      240

aggagctggt ggcgggcggc cccgaagcct tcgcggcctt cctgcgacgc gagcgcctgg      300

ctcgtttcct gaaccccgat gaggtgcacg ccattctgcg cgcggcggag aggccgggag      360

aggagggcgc ggcggcggcg gcggcggccg aggactcgtt cggctcctcg cacgactgct      420

cttcgggcac ctacttcccc gagcagtcgg acctggagcc accgctgttg gagcttggct      480

ggcccgcctt ctaccagggc gcctaccgcg gcgccacgcg tgtcgagacg cacttccagc      540

cccgcggcgc tggcgaaggt ggcccctacg gctgcaagga cgctctgcgc cagcagctcc      600

gctcggcgcg agaggtgatt gcagtggtca tggacgtgtt cacagacatc gacatcttca      660

gagacctgca agaaatatgc aggaaacagg gagttgctgt gtatatcctt ctggaccagg      720

ctctcctctc tcaatttctg gatatgtgca tggatctgaa agttcatcct gaacaggaaa      780

agttaatgac agttcggact atcacaggaa atatctacta tgcaaggtca ggaactaaga      840

ttattgggaa ggttcacgaa aagttcacgt tgattgatgg catccgcgtg gcaacaggct      900

cctacagttt tacatggacg gatggcaaat taaacagcag taacttggta attctgtctg      960

gccaagtggt tgaacacttt gatctggagt tccgaatcct gtatgcccag tccaagccca     1020

tcagccccaa actcctgtct cacttccaga gcagcaacaa gtttgatcac ctcaccaacc     1080

gaaaaccaca gtccaaggag ctcaccctgg gcaacctgct gcggatgcgg ctggctaggc     1140

tgtcaagtac tcccaggaag gcggacctgg acccagagat gcccgcagag ggcaaggcag     1200

agcgcaagcc ccatgactgt gagtcctcta ctgttagtga ggaagactac ttcagcagcc     1260

acagggacga gctccagagc agaaaggcca ttgacgctgc cactcaaaca gagccaggag     1320

aggagatgcc agggctgagt gtgagtgagg tgggaacaca aaccagcatc accacagcat     1380

gtgctggtac ccagactgca gtcatcacca ggatagcaag ctctcaaacc acgatttggt     1440

ccagatcgac cactactcag actgacatgg atgagaacat tctctttcct cgaggaactc     1500

aatctacaga agggtcacca gtctcaaaaa tgtctgtatc gagatcttcc agtttgaagt     1560

cttcctcctc tgtgtcttcc caaggctctg tggcaagctc cactggttct cccgcttcca     1620

tcagaaccac tgacttccac aatcctggct atcccaagta cctgggcacc ccccacctgg     1680

aactgtactt gagtgactca cttagaaact tgaacaaaga gcggcaattc cacttcgctg     1740

gtatcaggtc ccggctcaac cacatgctgg ctatgctgtc aaggagaaca ctctttactg     1800

aaaaccacct tggccttcat tctggcaatt tcagcagagt taatttgctt gctgttagag     1860

atgtagcact ttatccttcc tatcagtaac tgctccgtgt tcagactcct ggtttcttcc     1920

aggcttacag tggacatcat cagcttcctg ctttaaaaaa tatcttatgt ccctaattgc     1980

ctttctttta cctgactttg tcacctttgt tgtctttgaa ttctttaggc tgcatattat     2040

tttacatgct ttgttttgtc atgtatatac caggtattgg ttttatggtt taaacactat     2100

ggatacaggg gtttgttttg cacaatttta atagtcatgc actacataat gatgttttgg     2160

tcaatgacag accacgtata tgttggcagt ctcataagat tataatactg tatttttact     2220

ataccttttc tgtgtttaga tacaaatacc attatgttac agttgcctac agtattcagt     2280

gcagtaacat gatgtacagg tttgtagcct gttttgcatt tttcttaggt tgtatgctct     2340

tctgttttaa aggtttgaat caccagcatt tttgtgatca aaatcctatt tagaaaaaat     2400

aaaactactt tctgtttatc tctttagaaa aaaaaaaaaa aaaaa                     2445


<210>  1468
<211>  1114
<212>  DNA
<213>  homo sapiens

<400>  1468
cgagccgcga agattgtttt tgtcccgccg aaatcgagca aagcacgctg gaacttgtag       60

tccttgaggc cccttcccta ggtccttcga gctactccgt ctggccccgc cttttctctg      120

ctctcctgaa cctttaggct tgtctcggcc catttgaaga ccaggaagtt gatcaatccc      180

gaggctgctg agagacggtg gcgcgattgg gacagtcgcc agggatggct gagcgtgaag      240

atgcagcggg tgtccgggct gctctcctgg acgctgagca gagtcctgtg gctctccggc      300

ctctctgagc cgggagctgc ccggcagccc cggatcatgg aagagaaagc gctagaagtt      360

tatgatttga ttagaactat ccgggaccca gaaaagccca atactttaga agaactggaa      420

gtggtctcgg aaagttgtgt ggaagttcag gagataaatg aagaagaata tctggttatt      480

atcaggttca cgccaacagt acctcattgc tctttggcga ctcttattgg gctgtgctta      540

agagtaaaac ttcagcgatg tttaccattt aaacataagt tggaaatcta catttctgaa      600

ggaacccact caacagaaga agacatcaat aagcagataa atgacaaaga gcgagtggca      660

gctgcaatgg aaaaccccaa cttacgggaa attgtggaac agtgtgtcct tgaacctgac      720

tgatagctgt tttaagagcc actggcctgt aattgtttga tatatttgtt taaactcttt      780

gtataatgtc agagactcat gtttaataca taggtgattt gtacctcaga gtatttttta      840

aaggattctt tccaagcgag atttaattat aaggtagtac ctaatttgtt caatgtataa      900

cattctcagg atttgtaaca cttaaatgat cagacagaat aatattttct agttattatg      960

tgtaagatga gttgctattt ttctgatgct cattctgata caactatttt tcgtgtcaaa     1020

tatctactgt gcccaaatgt actcaattta aatcattact ctgtaaaata aataagcaga     1080

tgattcttat aatgaaaaaa aaaaaaaaaa aaaa                                 1114


<210>  1469
<211>  8789
<212>  DNA
<213>  homo sapiens

<400>  1469
atgctcagtg gcttctcgac aagttggcag caacaacacg gccctggtcg tcgtcgccgc       60

tgcggtaacg gagcggtttg ggtggcggag cctgcgttcg cgccttcccg ctctcctcgg      120

gaggcccttc ctgctctccc ctaggctccg cggccgccca gggggtggga gcgggtgagg      180

ggagccaggc gcccagcgag agaggccccc cgccgcaggg cggcccggga gctcgaggcg      240

gtccggcccg cgcgggcagc ggcgcggcgc tgaggagggg cggcctggcc gggacgcctc      300

ggggcggggg ccgaggagct ctccgggccg ccggggaaag ctacgggccc ggtgcgtccg      360

cggaccagca gcgcgggaga gcggactccc ctcgccaccg cccgagccca ggttatcctg      420

aatacatgtc taacaatttt ccttgcaacg ttagctgttg tttttcactg tttccaaagg      480

atcaaaattg cttcagaaat tggagacata tttgatttaa aaggaaaaac ttgaacaaat      540

ggacaatatg tctattacga atacaccaac aagtaatgat gcctgtctga gcattgtgca      600

tagtttgatg tgccatagac aaggtggaga gagtgaaaca tttgcaaaaa gagcaattga      660

aagtttggta aagaagctga aggagaaaaa agatgaattg gattctttaa taacagctat      720

aactacaaat ggagctcatc ctagtaaatg tgttaccata cagagaacat tggatgggag      780

gcttcaggtg gctggtcgga aaggatttcc tcatgtgatc tatgcccgtc tctggaggtg      840

gcctgatctt cacaaaaatg aactaaaaca tgttaaatat tgtcagtatg cgtttgactt      900

aaaatgtgat agtgtctgtg tgaatccata tcactacgaa cgagttgtat cacctggaat      960

tgatctctca ggattaacac tgcagagtaa tgctccatca agtatgatgg tgaaggatga     1020

atatgtgcat gactttgagg gacagccatc gttgtccact gaaggacatt caattcaaac     1080

catccagcat ccaccaagta atcgtgcatc gacagagaca tacagcaccc cagctctgtt     1140

agccccatct gagtctaatg ctaccagcac tgccaacttt cccaacattc ctgtggcttc     1200

cacaagtcag cctgccagta tactgggggg cagccatagt gaaggactgt tgcagatagc     1260

atcagggcct cagccaggac agcagcagaa tggatttact ggtcagccag ctacttacca     1320

tcataacagc actaccacct ggactggaag taggactgca ccatacacac ctaatttgcc     1380

tcaccaccaa aacggccatc ttcagcacca cccgcctatg ccgccccatc ccggacatta     1440

ctggcctgtt cacaatgagc ttgcattcca gcctcccatt tccaatcatc ctgctcctga     1500

gtattggtgt tccattgctt actttgaaat ggatgttcag gtaggagaga catttaaggt     1560

tccttcaagc tgccctattg ttactgttga tggatacgtg gacccttctg gaggagatcg     1620

cttttgtttg ggtcaactct ccaatgtcca caggacagaa gccattgaga gagcaaggtt     1680

gcacataggc aaaggtgtgc agttggaatg taaaggtgaa ggtgatgttt gggtcaggtg     1740

ccttagtgac cacgcggtct ttgtacagag ttactactta gacagagaag ctgggcgtgc     1800

acctggagat gctgttcata agatctaccc aagtgcatat ataaaggtct ttgatttgcg     1860

tcagtgtcat cgacagatgc agcagcaggc ggctactgca caagctgcag cagctgccca     1920

ggcagcagcc gtggcaggaa acatccctgg cccaggatca gtaggtggaa tagctccagc     1980

tatcagtctg tcagctgctg ctggaattgg tgttgatgac cttcgtcgct tatgcatact     2040

caggatgagt tttgtgaaag gctggggacc ggattaccca agacagagca tcaaagaaac     2100

accttgctgg attgaaattc acttacaccg ggccctccag ctcctagacg aagtacttca     2160

taccatgccg attgcagacc cacaaccttt agactgaggt cttttaccgt tggggccctt     2220

aaccttatca ggatggtgga ctacaaaata caatcctgtt tataatctga agatatattt     2280

cacttttgtt ctgctttatc ttttcataaa gggttgaaaa tgtgtttgct gccttgctcc     2340

tagcagacag aaactggatt aaaacaattt tttttttcct cttcagaact tgtcaggcat     2400

ggctcagagc ttgaagatta ggagaaacac attcttatta attcttcacc tgttatgtat     2460

gaaggaatca ttccagtgct agaaaattta gccctttaaa acgtcttaga gccttttatc     2520

tgcagaacat cgatatgtat atcattctac agaataatcc agtattgctg attttaaagg     2580

cagagaagtt ctcaaagtta attcacctat gttattttgt gtacaagttg ttattgttga     2640

acatacttca aaaataatgt gccatgtggg tgagttaatt ttaccaagag taactttact     2700

ctgtgtttaa aaagtaagtt aataatgtat tgtaatcttt catccaaaat attttttgca     2760

agttatatta gtgaagatgg tttcaattca gattgtcttg caacttcagt tttatttttg     2820

ccaaggcaaa aaactcttaa tctgtgtgta tattgagaat cccttaaaat taccagacaa     2880

aaaaatttaa aattacgttt gttattccta gtggatgact gttgatgaag tatacttttc     2940

ccctgttaaa cagtagttgt attcttctgt atttctaggc acaaggttgg ttgctaagaa     3000

gcctataaga ggaatttctt ttccttcatt catagggaaa ggttttgtat tttttaaaac     3060

actaaaagca gcgtcactct acctaatgtc tcactgttct gcaaaggtgg caatgcttaa     3120

actaaataat gaataaactg aatattttgg aaactgctaa attctatgtt aaatactgtg     3180

cagaataatg gaaacattac agttcataat aggtagtttg gatatttttg tacttgattt     3240

gatgtgactt tttttggtat aatgtttaaa tcatgtatgt tatgatattg tttaaaattc     3300

agtttttgta tcttggggca agactgcaaa cttttttata tcttttggtt attctaagcc     3360

ctttgccatc aatgatcata tcaattggca gtgactttgt atagagaatt taagtagaaa     3420

agttgcagat gtattgactg taccacagac acaatatgta tgctttttac ctagctggta     3480

gcataaataa aactgaatct caacatacaa agttgaattc taggtttgat ttttaagatt     3540

ttttttttct tttgcacttt tgagtccaat ctcagtgatg aggtaccttc tactaaatga     3600

caggcaacag ccagttctat tgggcagctt tgtttttttc cctcacactc taccgggact     3660

tccccatgga cattgtgtat catgtgtaga gttggttttt ttttttttta atttttattt     3720

tactatagca gaaatagacc tgattatcta caagatgata aatagattgt ctacaggata     3780

aatagtatga aataaaatca aggattatct ttcagatgtg tttacttttg cctggagaac     3840

ttttagctat agaaacactt gtgtgatgat agtcctcctt atatcacctg gaatgaacac     3900

agcttctact gccttgctca gaaggtcttt taaatagacc atcctagaaa ccactgagtt     3960

tgcttatttc tgtgatttaa acatagatct tgatccaagc tacatgactt ttgtctttaa     4020

ataacttatc taccacctca tttgtactct tgattactta caaattcttt cagtaaacac     4080

ctaattttct tctgtaaaag tttggtgatt taagttttat tggcagtttt ataaaaagac     4140

atcttctcta gaaattgcta actttaggtc cattttactg tgaatgagga ataggagtga     4200

gttttagaat aacagatttt taaaaatcca gatgatttga ttaaaacctt aatcatacat     4260

tgacataatt cattgcttct tttttttgag atatggagtc ttgctgtgtt gcccaggcag     4320

gagtgcagtg gtatgatctc agctcactgc aacctctgcc tcccgggttc aactgattct     4380

cctgcctcag cctccctggt agctaggatt acaggtgccc gccaccatgc ctggctaact     4440

tttgtagttt tagtagagac ggggttttgc ctgttggcca ggctggtctt gaactcctga     4500

cctcaagtga tccatccacc ttggcctccc aaagtgctgg gattacgggc gtgagccact     4560

gtccctggcc tcattgttcc cttttctact ttaaggaaag ttttcatgtt taatcatctg     4620

gggaaagtat gtgaaaaata tttgttaaga agtatctctt tggagccaag ccacctgtct     4680

tggtttcttt ctactaagag ccataaagta tagaaatact tctagttgtt aagtgcttat     4740

atttgtacct agatttagtc acacgctttt gagaaaacat ctagtatgtt atgatcagct     4800

attcctgaga gcttggttgt taatctatat ttctatttct tagtggtagt catctttgat     4860

gaataagact aaagattctc acaggtttaa aattttatgt ctactttaag ggtaaaatta     4920

tgaggttatg gttctgggtg ggttttctct agctaattca tatctcaaag agtctcaaaa     4980

tgttgaattt cagtgcaagc tgaatgagag atgagccatg tacacccacc gtaagacctc     5040

attccatgtt tgtccagtgc ctttcagtgc attatcaaag ggaatccttc atggtgttgc     5100

ctttattttc cggggagtag atcgtgggat atagtctatc tcatttttaa tagtttaccg     5160

cccctggtat acaaagataa tgacaataaa tcactgccat ataaccttgc tttttccaga     5220

aacatggctg ttttgtattg ctgtaaccac taaataggtt gcctatacca ttcctcctgt     5280

gaacagtgca gatttacagg ttgcatggtc tggcttaagg agagccatac ttgagacatg     5340

tgagtaaact gaactcatat tagctgtgct gcatttcaga cttaaaatcc atttttgtgg     5400

ggcagggtgt ggtgtgtaaa ggggggtgtt tgtaatacaa gttgaaggca aaataaaatg     5460

tcctgtctcc cagatgatat acatcttatt atttttaaag tttattgcta attgtaggaa     5520

ggtgagttgc aggtatcttt gactatggtc atctggggaa ggaaaatttt acattttact     5580

attaatgctc cttaagtgtc tatggaggtt aaagaataaa atggtaaatg tttctgtgcc     5640

tggtttgatg gtaactggtt aatagttact caccatttta tgcagagtca cattagttca     5700

caccctttct gagagccttt tgggagaagc agttttattc tctgagtgga acagagttct     5760

ttttgttgat aatttctagt ttgctccctt cgttattgcc aactttactg gcattttatt     5820

taatgatagc agattgggaa aatggcaaat ttaggttacg gaggtaaatg agtatatgaa     5880

agcaattacc tctaaagcca gttaacaatt attttgtagg tggggtacac tcagcttaaa     5940

gtaatgcatt tttttttccc gtaaaggcag aatccatctt gttgcagata gctatctaaa     6000

taatctcata tcctcttttg caaagactac agagaatagg ctatgacaat cttgttcaag     6060

cctttccatt tttttccctg ataactaagt aatttctttg aacataccaa gaagtatgta     6120

aaaagtccat ggccttattc atccacaaag tggcatccta ggcccagcct tatccctagc     6180

agttgtccca gtgctgctag gttgcttatc ttgtttatct ggaatcactg tggagtgaaa     6240

ttttccacat catccagaat tgccttattt aagaagtaaa acgttttaat ttttagcctt     6300

tttttggtgg agttatttaa tatgtatatc agaggatata ctagatggta acatttcttt     6360

ctgtgcttgg ctatctttgt ggacttcagg ggcttctaaa acagacagga ctgtgttgcc     6420

tttactaaat ggtctgagac agctatggtt ttgaattttt agtttttttt ttttaaccca     6480

cttcccctcc tggtctcttc cctctctgat aattaccatt catatgtgag tgttagtgtg     6540

cctcctttta gcattttctt cttctctttc tgattcttca tttctgactg cctaggcaag     6600

gaaaccagat aaccaaactt actagaacgt tctttaaaac acaagtacaa actctgggac     6660

aggacccaag acactttcct gtgaagtgct gaaaaagacc tcattgtatt ggcatttgat     6720

atcagtttga tgtagcttag agtgcttcct gattcttgct gagtttcagg tagttgagat     6780

agagagaagt gagtcatatt catattttcc cccttagaat aatattttga aaggtttcat     6840

tgcttccact tgaatgctgc tcttacaaaa actggggtta caagggttac taaattagca     6900

tcagtagcca gaggcaatac cgttgtctgg aggacaccag caaacaacac acaacaaagc     6960

aaaacaaacc ttgggaaact aaggccattt gttttgtttt ggtgtcccct ttgaagccct     7020

gccttctggc cttactcctg tacagatatt tttgacctat aggtgccttt atgagaattg     7080

agggtctgac atcctgcccc aaggagtagc taaagtaatt gctagtgttt tcagggattt     7140

taacatcaga ctggaatgaa tgaatgaaac tttttgtcct ttttttttct gttttttttt     7200

ttctaatgta gtaaggacta aggaaaacct ttggtgaaga caatcatttc tctctgttga     7260

tgtggatact tttcacaccg tttatttaaa tgctttctca ataggtccag agccagtgtt     7320

cttgttcaac ctgaaagtaa tggctctggg ttgggccaga cagttgcact ctctagtttg     7380

ccctctgcca caaatttgat gtgtgacctt tgggcaagtc atttatcttc tctgggcctt     7440

agttgcctca tctgtaaaat gagggagttg gagtagatta attattccag ctctgaaatt     7500

ctaagtgacc ttggctacct tgcagcagtt ttggatttct tccttatctt tgttctgctg     7560

tttgaggggg ctttttactt atttccatgt tattcaaagg agactaggct tgatatttta     7620

ttactgttct tttatggaca aaaggttaca tagtatgccc ttaagactta attttaacca     7680

aaggcctagc accaccttag gggctgcaat aaacacttaa cgcgcgtgcg cacgcgcgcg     7740

cgcacacaca cacacacaca cacacacaca cacaggtcag agtttaaggc tttcgagtca     7800

tgacattcta gcttttgaat tgcgtgcaca cacacacgca cgcacacact ctggtcagag     7860

tttattaagg ctttcgagtc atgacattat agcttttgag ttggtgtgtg tgacaccacc     7920

ctcctaagtg gtgtgtgctt gtaatttttt ttttcagtga aaatggattg aaaacctgtt     7980

gttaatgctt agtgatatta tgctcaaaac aaggaaattc ccttgaaccg tgtcaattaa     8040

actggtttat atgactcaag aaaacaatac cagtagatga ttattaactt tattcttggc     8100

tctttttagg tccattttga ttaagtgact tttggctgga tcattcagag ctctcttcta     8160

gcctaccctt ggatgagtac aattaatgaa attcatattt tcaaggacct gggagccttc     8220

cttggggctg ggttgagggt ggggggttgg ggagtcctgg tagaggccag ctttgtggta     8280

gctggagagg aagggatgaa accagctgct gttgcaaagg ctgcttgtca ttgatagaag     8340

gactcacggg cttggattga ttaagactaa acatggagtt ggcaaacttt cttcaagtat     8400

tgagttctgt tcaatgcatt ggacatgtga tttaagggaa aagtgtgaat gcttatagat     8460

gatgaaaacc tggtgggctg cagagcccag tttagaagaa gtgagttggg ggttggggac     8520

agatttggtg gtggtatttc ccaactgttt cctcccctaa attcagagga atgcagctat     8580

gccagaagcc agagaagagc cactcgtagc ttctgctttg gggacaactg gtcagttgaa     8640

agtcccagga gttcctttgt ggctttctgt atacttttgc ctggttaaag tctgtggcta     8700

aaaaatagtc gaacctttct tgagaactct gtaacaaagt atgtttttga ttaaaagaga     8760

aagccaacta aaaaaaaaaa aaaaaaaaa                                       8789


<210>  1470
<211>  5402
<212>  DNA
<213>  homo sapiens

<400>  1470
gcggccgcgg cggcgggagg cggcgggagg cgggcggagg aggaggcgga ggaggcggga       60

gctgagctga gtggggcggg cggcggcggg gcccgagccg gagaagatgg cggtgcggaa      120

gaaggacggc ggccccaacg tgaagtacta cgaggccgcg gacaccgtga cccagttcga      180

caacgtgcgg ctgtggctcg gcaagaacta caagaagtat atacaagctg aaccacccac      240

caacaagtcc ctgtctagcc tggttgtaca gttgctacaa tttcaggaag aagtttttgg      300

caaacatgtc agcaatgcac cgctcactaa actgccgatc aaatgtttcc tagatttcaa      360

agcgggaggc tccttgtgcc acattcttgc agctgcctac aaattcaaga gtgaccaggg      420

atggcggcgt tacgatttcc agaatccatc acgcatggac cgcaatgtgg aaatgtttat      480

gaccattgag aagtccttgg tgcagaataa ttgcctgtct cgacctaaca tttttctgtg      540

cccagaaatt gagcccaaac tactagggaa attaaaggac attatcaaga gacaccaggg      600

aacagtcact gaggataaga acaatgcctc ccatgttgtg tatcctgtcc cggggaatct      660

agaagaagag gaatgggtac gaccagtcat gaagagggat aagcaggttc ttctgcactg      720

gggctactat cctgacagtt acgacacgtg gatcccagcg agtgaaattg aggcatctgt      780

ggaagatgct ccaactcctg agaaacctag gaaggttcat gcaaagtgga tcctggacac      840

cgacaccttc aatgaatgga tgaatgagga agactatgaa gtaaatgatg acaaaaaccc      900

tgtctcccgc cgaaagaaga tttcagccaa gacactgaca gatgaggtga acagcccaga      960

ttcagatcga cgggacaaga aggggggaaa ctataagaag aggaagcgct ccccctctcc     1020

ttcaccaacc ccagaagcaa agaagaaaaa tgctaagaaa ggtccctcaa caccttacac     1080

taagtcaaag cgtggccaca gagaagagga gcaagaagac ctgacaaagg acatggacga     1140

gccctcacca gtccccaatg tagaagaggt gacacttccc aaaacagtca acacaaagaa     1200

agactcagag tcggccccag tcaaaggcgg caccatgacc gacctggatg aacaggaaga     1260

tgaaagcatg gagacgacgg gcaaggatga ggatgagaac agtacgggga acaagggaga     1320

gcagaccaag aatccagacc tgcatgagga caatgtgact gaacagaccc accacatcat     1380

cattcccagc tacgctgcct ggtttgacta caatagtgtt catgccattg agcggagggc     1440

tctccccgag ttcttcaacg gcaagaacaa gtccaagact ccagagatct acctggccta     1500

tcgaaacttt atgattgaca cttaccgact gaacccccaa gagtatctta cctctaccgc     1560

ctgccgccga aacctagcgg gtgatgtctg tgccatcatg agggtccatg ccttcctaga     1620

acagtggggt cttattaact accaggtgga tgctgagagt cgaccaaccc caatggggcc     1680

tccgcctacc tctcacttcc atgtcttggc tgacacacca tcagggctgg tgcctctgca     1740

gcccaagaca cctcagggcc gccaggttga tgctgatacc aaggctgggc gaaagggcaa     1800

agagctggat gacctggtgc cagagacggc taagggcaag ccagagctgc agacctctgc     1860

ttcccaacaa atgctcaact ttcctgacaa aggcaaagag aaaccaacag acatgcaaaa     1920

ctttgggctg cgcacagaca tgtacacaaa aaagaatgtt ccctccaaga gcaaggctgc     1980

agccagtgcc actcgtgagt ggacagaaca ggaaaccctg cttctcctgg aggcactgga     2040

aatgtacaaa gatgactgga acaaagtgtc cgagcatgtg ggaagccgca cacaggacga     2100

gtgcatcttg cattttcttc gtcttcccat tgaagaccca tacctggagg actcagaggc     2160

ctccctaggc cccctggcct accaacccat ccccttcagt cagtcgggca accctgttat     2220

gagcactgtt gccttcctgg cctctgtcgt cgatccccga gtcgcctctg ctgctgcaaa     2280

gtcagcccta gaggagttct ccaaaatgaa ggaagaggta cccacggcct tggtggaggc     2340

ccatgttcga aaagtggaag aagcagccaa agtaacaggc aaggcggacc ctgccttcgg     2400

tctggaaagc agtggcattg caggaaccac ctctgatgag cctgagcgga ttgaggagag     2460

cgggaatgac gaggctcggg tggaaggcca ggccacagat gagaagaagg agcccaagga     2520

accccgagaa ggagggggtg ctatagagga ggaagcaaaa gagaaaacca gcgaggctcc     2580

caagaaggat gaggagaaag ggaaagaagg cgacagtgag aaggagtccg agaagagtga     2640

tggagaccca atagtcgatc ctgagaagga gaaggagcca aaggaagggc aggaggaagt     2700

gctgaaggaa gtggtggagt ctgaggggga aaggaagaca aaggtggagc gggacattgg     2760

cgagggcaac ctctccaccg ctgctgccgc cgccctggcc gccgccgcag tgaaagctaa     2820

gcacttggct gctgttgagg aaaggaagat caaatctttg gtggccctgc tggtggagac     2880

ccagatgaaa aagttggaga tcaaacttcg gcactttgag gagctggaga ctatcatgga     2940

ccgggagcga gaagcactgg agtatcagag gcagcagctc ctggccgaca gacaagcctt     3000

ccacatggag cagctgaagt atgcggagat gagggctcgg cagcagcact tccaacagat     3060

gcaccaacag cagcagcagc caccaccagc cctgccccca ggctcccagc ctatcccccc     3120

aacaggggct gctgggccac ccgcagtcca tggcttggct gtggctccag cctctgtagt     3180

ccctgctcct gctggcagtg gggcccctcc aggaagtttg ggcccttctg aacagattgg     3240

gcaggcaggg tcaactgcag ggccacagca gcagcaacca gctggagccc cccagcctgg     3300

ggcagtccca ccaggggttc ccccccctgg accccatggc ccctcaccgt tccccaacca     3360

acaaactcct ccctcaatga tgccaggggc agtgccaggc agcgggcacc caggcgtggc     3420

ggcccaaagc cctgccattg tggcagctgt tcagggcaac ctcctgccca gtgccagccc     3480

actgccagac ccaggcaccc ccctgcctcc agaccccaca gccccgagcc caggcacggt     3540

cacccctgtg ccacctccac agtgaggagc cagccagaca tctctccccc tcaccccctg     3600

tggacatcac ggttccagga acagcccttc ccccaccact gggaccctcc ccagcctgga     3660

gagttcatca ctacgtaagg aaagctcctt ccgcccctcc aaagccctca ccatgcctaa     3720

cagaggcatg catttttata tcagattatt caaggacttc tgtttaaaag atgtttataa     3780

tgtctgggag agaggatagg atgggaatgc tgccctaaag gaagggctgg tgaaaggtgt     3840

ttatacaagg ttctattaac cacttctaag ggtacacctc cctccaaact actgcatttt     3900

ctatggatta aaaaaaaaaa aaaaaagtag attttaaaaa gccacattgg agctcccttc     3960

tacccactaa aaaataacca atttttacat tttttgaggg ggagtgagtt ttaggaaagg     4020

ggaattaaga ttccagggag agctctgggg atagaacagg gcgcagattc catctctccc     4080

caagcccctt tttagtgact aagtcaaggc cccaactccc ctcccccacc ctacgctgag     4140

cttattcgag ttcattcgta ctaataatcc ctcctgcggc ttcctcattg ttgctgtttt     4200

aggccacccc agctcagcca atgattcctt tccctctgaa tgtcagtttt gtttttaaaa     4260

gtcacttgct tagttgatgt cagcgtatgt gtatttggtg gggaaaacct aatttcgggg     4320

atttctgtgg taggtaatag gagaagaaag ggcactgggg gctgttctcc ttccttccct     4380

gggctgtatc catggactcc tggaaggcac agagaaggga gctataagag gatgtgaagt     4440

tttaaaacct gaaattgttt tttaaagcac ttaagcacct ccatattatg acttggtggg     4500

tcacccctta gcttcctccc tctcccacca agactatgag aacttcagct gatagctggg     4560

ggctccccag atgaggatgc agggatttgg gagcagtgga agagggtgcc caaccttggg     4620

ttggaccaac ccttggctcg cagctcaact ctgcttcccg cattcctgct ccacgtgtcc     4680

cagcttctcc cctgtgacgg gaaggcaggt gtgactccag gctctgcact ggttcttctt     4740

ggttcctccc accaggccct ttgttcctca tgtccccatg tttctctccc tctgcgtctt     4800

agcacctttc ttctgttcaa agttttctgt aaattttctc tttttttctt tctttctttt     4860

tttttttttt ataaattaat ttgctttcag ttccatcttg tgggtgcatt ctgtgttctt     4920

acctgtggct gtcaggcagg gggattgtga tgggagcagc tttcctggag tccttcacag     4980

cggcgtttac ctgggccgaa agacactctg caagccacac ggcctacaga cactgcgcct     5040

ccccacaaaa cacgaacggc agcacaactg tcgagactat gtgctggtat aggagcagag     5100

gctctcacct gccctaaaag ctgtttaaga cttggaagga cattcccaca acatggaatt     5160

ttgtatctct gtcccttcag aagtagtggt ttcactcctt cccttattag agaggaggca     5220

agccccttac ctacttttgt tataattggc ccttcaccct gctgaggtga cggacaggct     5280

taggcagtgc taataatggc ctggctttag ctccaataaa cactccacag gcttccccac     5340

aaaaggcctt attgggagct tgggagggcg ggggccagat ttaaggagct ggaagggtag     5400

ga                                                                    5402


<210>  1471
<211>  1908
<212>  DNA
<213>  homo sapiens

<400>  1471
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag caggaccatt      120

ctggctgctg tctggacaag aagtcgtagg gggtgagggt ggaagctggg aaacccacag      180

gaggcaacca cactagttta gatcttctgg tgaccccact tctcgctgct catgccgctg      240

ggactggggc ggcggaaaaa ggcgccccct ctagtggaaa atgaggaggc tgagccaggc      300

cgtggagggc tgggcgtggg ggagccaggg cctctgggcg gaggtgggtc ggggggcccc      360

caaatgggct tgcccccccc tcccccagcc ctgcggcccc gcctcgtgtt ccacacccag      420

ctggcccatg gcagtcccac tggccgcatc gagggcttca ccaacgtcaa ggagctgtat      480

ggcaagatcg ccgaggcctt ccgcctgcca actgccgagg tgatgttctg caccctgaac      540

acccacaaag tggacatgga caagctcctg gggggccaga tcgggctgga ggacttcatc      600

ttcgcccacg tgaaggggca gcgcaaggag gtggaggtgt tcaagtcgga ggatgcactc      660

gggctcacca tcacggacaa cggggctggc tacgccttca tcaagcgcat caaggagggc      720

agcgtgatcg accacatcca cctcatcagc gtgggcgaca tgatcgaggc cattaacggg      780

cagagcctgc tgggctgccg gcactacgag gtggcccggc tgctcaagga gctgccccga      840

ggccgtacct tcacgctgaa gctcacggag cctcgcaagg ccttcgacat gatcagccag      900

cgttcagcgg gtggccgccc tggctctggc ccacaactgg gcactggccg agggaccctg      960

cggctccgat cccggggccc cgccacggtg gaggatctgc cctctgcctt tgaagagaag     1020

gccattgaga aggtggatga cctgctggag agttacatgg gtatcaggga cacggagctg     1080

gcggccacca tggtggagct gggaaaggac aaaaggaacc cggatgagct ggccgaggcc     1140

ctggacgaac ggctgggtga ctttgccttc cctgacgagt tcgtctttga cgtctggggc     1200

gccattgggg acgccaaggt cggccgctac taggactgcc cccggaccct gcgatgatga     1260

cccgggcgca acctggtggg ggcccccagc agggacactg acgtcaggac ccgagcctcc     1320

agcctgagcc tagctcagca gcccaaggac gatggtgagg ggaggtgggg ccaggccccc     1380

tgccccgctc caatcggtac catcccctcc ctggttccca gtctggccgg ggtccccggc     1440

ccccctgtgc cctgttcccc acctacctca gctgggtcag gcacagggag gggagggatc     1500

agccaaattg ggcggccacc cccgcctcca ccactttcca ccatcagctg ccaaactggt     1560

ccctctgtct ccctggggcc ttgggttctg tttgggggtc atgaccttcc tagtttcctg     1620

acgcagggaa tacaggggag agggttgtcc ttccccccag caaatgcaat aatgccctca     1680

cccctcctga gaggagcccc ctccctgtgg agcctgttac ctccgcattt gacacgagtc     1740

tgctgtgaac cccgcaacct cctccccacc tcccatctct ccttccaggc ccatccctgg     1800

cccagagcag gagggaggga gggacgatgg cggtgggttt ttgtatctga atttgctgtc     1860

ttgaacataa agaatctatc tgctgttgga aaaaaaaaaa aaaaaaaa                  1908


<210>  1472
<211>  1590
<212>  DNA
<213>  homo sapiens

<400>  1472
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag caggaccatt      120

ctggctgctg tctggacaag aagtcgtagg gggtgagggt ggaagctggg aaacccacag      180

gaggcaacca cactagttta ggtgatgttc tgcaccctga acacccacaa agtggacatg      240

gacaagctcc tggggggcca gatcgggctg gaggacttca tcttcgccca cgtgaagggg      300

cagcgcaagg aggtggaggt gttcaagtcg gaggatgcac tcgggctcac catcacggac      360

aacggggctg gctacgcctt catcaagcgc atcaaggagg gcagcgtgat cgaccacatc      420

cacctcatca gcgtgggcga catgatcgag gccattaacg ggcagagcct gctgggctgc      480

cggcactacg aggtggcccg gctgctcaag gagctgcccc gaggccgtac cttcacgctg      540

aagctcacgg agcctcgcaa ggccttcgac atgatcagcc agcgttcagc gggtggccgc      600

cctggctctg gcccacaact gggcactggc cgagggaccc tgcggctccg atcccggggc      660

cccgccacgg tggaggatct gccctctgcc tttgaagaga aggccattga gaaggtggat      720

gacctgctgg agagttacat gggtatcagg gacacggagc tggcggccac catggtggag      780

ctgggaaagg acaaaaggaa cccggatgag ctggccgagg ccctggacga acggctgggt      840

gactttgcct tccctgacga gttcgtcttt gacgtctggg gcgccattgg ggacgccaag      900

gtcggccgct actaggactg cccccggacc ctgcgatgat gacccgggcg caacctggtg      960

ggggccccca gcagggacac tgacgtcagg acccgagcct ccagcctgag cctagctcag     1020

cagcccaagg acgatggtga ggggaggtgg ggccaggccc cctgccccgc tccaatcggt     1080

accatcccct ccctggttcc cagtctggcc ggggtccccg gcccccctgt gccctgttcc     1140

ccacctacct cagctgggtc aggcacaggg aggggaggga tcagccaaat tgggcggcca     1200

cccccgcctc caccactttc caccatcagc tgccaaactg gtccctctgt ctccctgggg     1260

ccttgggttc tgtttggggg tcatgacctt cctagtttcc tgacgcaggg aatacagggg     1320

agagggttgt ccttcccccc agcaaatgca ataatgccct cacccctcct gagaggagcc     1380

ccctccctgt ggagcctgtt acctccgcat ttgacacgag tctgctgtga accccgcaac     1440

ctcctcccca cctcccatct ctccttccag gcccatccct ggcccagagc aggagggagg     1500

gagggacgat ggcggtgggt ttttgtatct gaatttgctg tcttgaacat aaagaatcta     1560

tctgctgttg gaaaaaaaaa aaaaaaaaaa                                      1590


<210>  1473
<211>  1820
<212>  DNA
<213>  homo sapiens

<400>  1473
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag cagatcttct      120

ggtgacccca cttctcgctg ctcatgccgc tgggactggg gcggcggaaa aaggcgcccc      180

ctctagtgga aaatgaggag gctgagccag gccgtggagg gctgggcgtg ggggagccag      240

ggcctctggg cggaggtggg tcggggggcc cccaaatggg cttgcccccc cctcccccag      300

ccctgcggcc ccgcctcgtg ttccacaccc agctggccca tggcagtccc actggccgca      360

tcgagggctt caccaacgtc aaggagctgt atggcaagat cgccgaggcc ttccgcctgc      420

caactgccga ggtgatgttc tgcaccctga acacccacaa agtggacatg gacaagctcc      480

tggggggcca gatcgggctg gaggacttca tcttcgccca cgtgaagggg cagcgcaagg      540

aggtggaggt gttcaagtcg gaggatgcac tcgggctcac catcacggac aacggggctg      600

gctacgcctt catcaagcgc atcaaggagg gcagcgtgat cgaccacatc cacctcatca      660

gcgtgggcga catgatcgag gccattaacg ggcagagcct gctgggctgc cggcactacg      720

aggtggcccg gctgctcaag gagctgcccc gaggccgtac cttcacgctg aagctcacgg      780

agcctcgcaa ggccttcgac atgatcagcc agcgttcagc gggtggccgc cctggctctg      840

gcccacaact gggcactggc cgagggaccc tgcggctccg atcccggggc cccgccacgg      900

tggaggatct gccctctgcc tttgaagaga aggccattga gaaggtggat gacctgctgg      960

agagttacat gggtatcagg gacacggagc tggcggccac catggtggag ctgggaaagg     1020

acaaaaggaa cccggatgag ctggccgagg ccctggacga acggctgggt gactttgcct     1080

tccctgacga gttcgtcttt gacgtctggg gcgccattgg ggacgccaag gtcggccgct     1140

actaggactg cccccggacc ctgcgatgat gacccgggcg caacctggtg ggggccccca     1200

gcagggacac tgacgtcagg acccgagcct ccagcctgag cctagctcag cagcccaagg     1260

acgatggtga ggggaggtgg ggccaggccc cctgccccgc tccaatcggt accatcccct     1320

ccctggttcc cagtctggcc ggggtccccg gcccccctgt gccctgttcc ccacctacct     1380

cagctgggtc aggcacaggg aggggaggga tcagccaaat tgggcggcca cccccgcctc     1440

caccactttc caccatcagc tgccaaactg gtccctctgt ctccctgggg ccttgggttc     1500

tgtttggggg tcatgacctt cctagtttcc tgacgcaggg aatacagggg agagggttgt     1560

ccttcccccc agcaaatgca ataatgccct cacccctcct gagaggagcc ccctccctgt     1620

ggagcctgtt acctccgcat ttgacacgag tctgctgtga accccgcaac ctcctcccca     1680

cctcccatct ctccttccag gcccatccct ggcccagagc aggagggagg gagggacgat     1740

ggcggtgggt ttttgtatct gaatttgctg tcttgaacat aaagaatcta tctgctgttg     1800

gaaaaaaaaa aaaaaaaaaa                                                 1820


<210>  1474
<211>  1502
<212>  DNA
<213>  homo sapiens

<400>  1474
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag caggtgatgt      120

tctgcaccct gaacacccac aaagtggaca tggacaagct cctggggggc cagatcgggc      180

tggaggactt catcttcgcc cacgtgaagg ggcagcgcaa ggaggtggag gtgttcaagt      240

cggaggatgc actcgggctc accatcacgg acaacggggc tggctacgcc ttcatcaagc      300

gcatcaagga gggcagcgtg atcgaccaca tccacctcat cagcgtgggc gacatgatcg      360

aggccattaa cgggcagagc ctgctgggct gccggcacta cgaggtggcc cggctgctca      420

aggagctgcc ccgaggccgt accttcacgc tgaagctcac ggagcctcgc aaggccttcg      480

acatgatcag ccagcgttca gcgggtggcc gccctggctc tggcccacaa ctgggcactg      540

gccgagggac cctgcggctc cgatcccggg gccccgccac ggtggaggat ctgccctctg      600

cctttgaaga gaaggccatt gagaaggtgg atgacctgct ggagagttac atgggtatca      660

gggacacgga gctggcggcc accatggtgg agctgggaaa ggacaaaagg aacccggatg      720

agctggccga ggccctggac gaacggctgg gtgactttgc cttccctgac gagttcgtct      780

ttgacgtctg gggcgccatt ggggacgcca aggtcggccg ctactaggac tgcccccgga      840

ccctgcgatg atgacccggg cgcaacctgg tgggggcccc cagcagggac actgacgtca      900

ggacccgagc ctccagcctg agcctagctc agcagcccaa ggacgatggt gaggggaggt      960

ggggccaggc cccctgcccc gctccaatcg gtaccatccc ctccctggtt cccagtctgg     1020

ccggggtccc cggcccccct gtgccctgtt ccccacctac ctcagctggg tcaggcacag     1080

ggaggggagg gatcagccaa attgggcggc cacccccgcc tccaccactt tccaccatca     1140

gctgccaaac tggtccctct gtctccctgg ggccttgggt tctgtttggg ggtcatgacc     1200

ttcctagttt cctgacgcag ggaatacagg ggagagggtt gtccttcccc ccagcaaatg     1260

caataatgcc ctcacccctc ctgagaggag ccccctccct gtggagcctg ttacctccgc     1320

atttgacacg agtctgctgt gaaccccgca acctcctccc cacctcccat ctctccttcc     1380

aggcccatcc ctggcccaga gcaggaggga gggagggacg atggcggtgg gtttttgtat     1440

ctgaatttgc tgtcttgaac ataaagaatc tatctgctgt tggaaaaaaa aaaaaaaaaa     1500

aa                                                                    1502


<210>  1475
<211>  1908
<212>  DNA
<213>  homo sapiens

<400>  1475
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag caggaccatt      120

ctggctgctg tctggacaag aagtcgtagg gggtgagggt ggaagctggg aaacccacag      180

gaggcaacca cactagttta gatcttctgg tgaccccact tctcgctgct catgccgctg      240

ggactggggc ggcggaaaaa ggcgccccct ctagtggaaa atgaggaggc tgagccaggc      300

cgtggagggc tgggcgtggg ggagccaggg cctctgggcg gaggtgggtc ggggggcccc      360

caaatgggct tgcccccccc tcccccagcc ctgcggcccc gcctcgtgtt ccacacccag      420

ctggcccatg gcagtcccac tggccgcatc gagggcttca ccaacgtcaa ggagctgtat      480

ggcaagatcg ccgaggcctt ccgcctgcca actgccgagg tgatgttctg caccctgaac      540

acccacaaag tggacatgga caagctcctg gggggccaga tcgggctgga ggacttcatc      600

ttcgcccacg tgaaggggca gcgcaaggag gtggaggtgt tcaagtcgga ggatgcactc      660

gggctcacca tcacggacaa cggggctggc tacgccttca tcaagcgcat caaggagggc      720

agcgtgatcg accacatcca cctcatcagc gtgggcgaca tgatcgaggc cattaacggg      780

cagagcctgc tgggctgccg gcactacgag gtggcccggc tgctcaagga gctgccccga      840

ggccgtacct tcacgctgaa gctcacggag cctcgcaagg ccttcgacat gatcagccag      900

cgttcagcgg gtggccgccc tggctctggc ccacaactgg gcactggccg agggaccctg      960

cggctccgat cccggggccc cgccacggtg gaggatctgc cctctgcctt tgaagagaag     1020

gccattgaga aggtggatga cctgctggag agttacatgg gtatcaggga cacggagctg     1080

gcggccacca tggtggagct gggaaaggac aaaaggaacc cggatgagct ggccgaggcc     1140

ctggacgaac ggctgggtga ctttgccttc cctgacgagt tcgtctttga cgtctggggc     1200

gccattgggg acgccaaggt cggccgctac taggactgcc cccggaccct gcgatgatga     1260

cccgggcgca acctggtggg ggcccccagc agggacactg acgtcaggac ccgagcctcc     1320

agcctgagcc tagctcagca gcccaaggac gatggtgagg ggaggtgggg ccaggccccc     1380

tgccccgctc caatcggtac catcccctcc ctggttccca gtctggccgg ggtccccggc     1440

ccccctgtgc cctgttcccc acctacctca gctgggtcag gcacagggag gggagggatc     1500

agccaaattg ggcggccacc cccgcctcca ccactttcca ccatcagctg ccaaactggt     1560

ccctctgtct ccctggggcc ttgggttctg tttgggggtc atgaccttcc tagtttcctg     1620

acgcagggaa tacaggggag agggttgtcc ttccccccag caaatgcaat aatgccctca     1680

cccctcctga gaggagcccc ctccctgtgg agcctgttac ctccgcattt gacacgagtc     1740

tgctgtgaac cccgcaacct cctccccacc tcccatctct ccttccaggc ccatccctgg     1800

cccagagcag gagggaggga gggacgatgg cggtgggttt ttgtatctga atttgctgtc     1860

ttgaacataa agaatctatc tgctgttgga aaaaaaaaaa aaaaaaaa                  1908


<210>  1476
<211>  5481
<212>  DNA
<213>  homo sapiens

<400>  1476
agaacgagtt ccggtctggc cgaggcttgt ctcctaaaaa tagccccggt gtggggatcc       60

gtgcgcggat gtcccggcga gtcccgggct gaaagaggcg gctccgggcg gcgcgaagcg      120

ctggtggcgg gcccgggctg cggcgtgtgc gcgcccgcca gctgctccgg agatacgatc      180

ttgtagaaaa tttcagctgt agcccttgga ctagaagctg aaataacaga agctgtgtac      240

gatgcattag ggtattgaag aaaattaact tttgaattaa atatttggaa tataaggaaa      300

taaggaaagt tgactgaaaa tggggcggaa gaaaatacaa atcacacgca taatggatga      360

aaggaaccga caggtcactt ttacaaagag aaagtttgga ttaatgaaga aagcctatga      420

acttagtgtg ctctgtgact gtgaaatagc actcatcatt ttcaacagct ctaacaaact      480

gtttcaatat gctagcactg atatggacaa agttcttctc aagtatacag aatataatga      540

acctcatgaa agcagaacca actcggatat tgttgagact ttaagaaaga aaggccttaa      600

tggttgtgag agccctgatg ctgacgatta ctttgagcac agtccactct cggaggacag      660

attcagcaaa ctaaatgaag atagtgattt tattttcaaa cgaggccctc ctggtctgcc      720

acctcagaac ttttcaatgt ctgtcacagt tccagtgacc agccccaatg ctttgtccta      780

cactaaccca gggagttcac tggtgtcccc atctttggca gccagctcaa cgttaacaga      840

ttcaagcatg ctctctccac ctcaaaccac attacataga aatgtgtctc ctggagctcc      900

tcagagacca ccaagtactg gcaatgcagg tgggatgttg agcactacag acctcacagt      960

gccaaatgga gctggaagca gtccagtggg gaatggattt gtaaactcaa gagcttctcc     1020

aaatttgatt ggagctactg gtgcaaatag cttaggcaaa gtcatgccta caaagtctcc     1080

ccctccacca ggtggtggta atcttggaat gaacagtagg aaaccagatc ttcgagttgt     1140

catcccccct tcaagcaagg gcatgatgcc tccactaaat acccaaagga tcagtagttc     1200

tcaagccact caacctcttg ctaccccagt cgtgtctgtg acaaccccaa gcttgcctcc     1260

gcaaggactt gtgtactcag caatgccgac tgcctacaac actgattatt cactgaccag     1320

cgctgacctg tcagcccttc aaggcttcaa ctcgccagga atgctgtcgc tgggacaggt     1380

gtcggcctgg cagcagcacc acctaggaca agcagccctc agctctcttg ttgctggagg     1440

gcagttatct cagggttcca atttatccat taataccaac caaaacatca gcatcaagtc     1500

cgaaccgatt tcacctcctc gggatcgtat gaccccatcg ggcttccagc agcagcagca     1560

gcagcagcag cagcagcagc cgccgccacc accgcagccc cagccacaac ccccgcagcc     1620

ccagccccga caggaaatgg ggcgctcccc tgtggacagt ctgagcagct ctagtagctc     1680

ctatgatggc agtgatcggg aggatccacg gggcgacttc cattctccaa ttgtgcttgg     1740

ccgaccccca aacactgagg acagagaaag cccttctgta aagcgaatga ggatggacgc     1800

gtgggtgacc taaggcttcc aagctgatgt ttgtactttt gtgttactgc agtgacctgc     1860

cctacatatc taaatcggta aataaggaca tgagttaaat atatttatat gtacatacat     1920

atatatatcc ctttacatat atatgtatgt gggtgtgagt gtgtatgtgt gggtgtgtgt     1980

tacatacaca gaatcaggca cttacctgca aactccttgt aggtctgcag atgtgtgtcc     2040

catggcagac aaagcaccct gtaggcacag acaagtctgg cacttccttg gactacttgt     2100

ttcgtaaaga taaccagttt ttgcagagaa acgtgtaccc atatataatt ctcccacact     2160

agcttgcaga aacctagagg gccccctact tgttttattt aactgtgcag tgactgtagt     2220

tacttaagag aaaatgcttt gtagaacaga gcagtagaaa agcaggaacc aagaaagcaa     2280

tactgtacat aaaatgtcat ttatattttc caacctggca tgggtgtctg ttgcaaaggg     2340

gtgcatggga aagggctgtt gatattaaaa acaaacaaaa caaaaaagcc ccacacataa     2400

ctgttttgca cgtgcaaaaa tgtattgggt caagaagtga tctttagcta ataaagaaag     2460

agaatagaaa acacgcatga gatattcaga aaatactagc ctagaaatat agagcattaa     2520

caaagtaaaa ttaatatatt aagttataat tggaatatgt cagaagtttc tttttacatt     2580

catatcttaa aaattaaaga aactgatttt agctcatgta tattttatat gaaagaaaac     2640

acccttatga attgatgact atatataaaa ttatattcac tacttttgaa cacattctgc     2700

tatgaattat ttatataagc caaagctata tgttgtaact tttttttaga gaatagcttt     2760

atcttggttt aactctttag ttttatttta agaggggaaa acaaaaatat cttgcaagca     2820

gaaccttgga aaaaaaaagc catgaacact tattctaaat gtaaattaaa agttgagcca     2880

aactctttgt gtatatagca tcttaaatat attatcacct ttgatgtaag tacctatgta     2940

ttgtatggtc accagattaa aaagtatatt tttgtggatt gccgccaatc tggggggaaa     3000

aggcgaggtc ctttattaag tattcactgt ttaatattta ctattttgtt aaatatactg     3060

tactttggat tttaattatt agcccagttt tttcagagga ttgtataaag gggtttctcc     3120

cctcactggt ggtgaatgtg tgatgttaca ttgtaatctt tgtgctgtat gggttgagca     3180

tcattatata ttttgtatgt gtacataaat agcaaagtgg caaaaaaaat tggtgttaag     3240

ttcatcctgc ataagtataa aatgtgttgt aacagatttt gtaaggcatt atttaaaact     3300

tgccttttgt gaggaaaaaa tgtagtagaa aaagctgacc taatttaatt aatattagag     3360

aaaatggcaa aatagtagat gagcacaaag gttttataag tggtaaatga ttaggggaaa     3420

ataatcatgg ggaaagggat cttttttcct tgaccctctg aaaacagaac gatgcagctg     3480

gttacaaaat cctaccgtta tcagctcttc tgcacattgc agtgatgctt tggtatgcgg     3540

ggagaaacac tcttagggtg ctggtccttg gcatgactct tgccattcta attggaatta     3600

gtgccaccct cagcttggat tttgaacaag gccttattct ttcaggaaga caactaatgg     3660

atgatagcaa gttcatccac ttactgggct tgtgccatga gcaaaattca aagtcctgta     3720

tatctttcat tgtagatttt taaatactcc ttttcctaaa aaactcaagg gtttaaaaat     3780

tgctatttta tattttaaat gatattgagc agctacctac aatttctatg tacattttgt     3840

tccccccccc ccaccccccc cccaaattac gttccttttg acattttcct catctgctgt     3900

ttgtgacaag tcatcagcca gatttcctga ctgacacata ggtatgatca gtgcaggaga     3960

gacctgcgca ccacaggctg caaactggag gttctgttct catggcagtt tgggcagtaa     4020

cttttgagag aggccaaaaa aaggaggatg acatgctgtc tcctctcttc agtatagaca     4080

ttaggctctt attcagaaag gatttttctt taaaaatgta cttactttac tgaactactt     4140

acaggcacat ttcttcataa ggccacacct aatccaaaca agacagtctc ccaacactga     4200

agttccaaaa taatccttac cactttgtaa accatttata gctttgaaag tgttaagtga     4260

ttccttcgtt attatttatg catgttcatg aacttctgct gtacattgga ataggagtta     4320

acacattcac atttactgtc tattttcttg tgtgccttat gagatggctt ttctgactgt     4380

atctcaatag tctttctttc tatgcaggtt tataatcagt acaactactg ttttctaaaa     4440

tactactact caaggctcgg agtttgtatt taaattacac tgaccaagta acaatgtatt     4500

ccatttcagg aactgaatat ttgactgtta acctttttcc catacgtcca gtgtggcatg     4560

gagcatatgg acttgacaga catctctcac ccagacgccc acgtgtgaac acacccacat     4620

ccacatctct gggtggaaac cagcctagag aggggacgac gctaatggtg ttgctttaga     4680

accgtctttt cttacccttt tagactcgtg ttttgtatga gacaccattg caagaaaatt     4740

ttatccctcc agaagtattt tattactaaa gaacaaaagc aaaaaaagct taaattgcac     4800

tggttaaagt acagtttcca acagctgtcc ttcctcagta ctctaatggc cactccaccg     4860

cgagtggaag tcactgttgt gtgtacacag gtggtcccaa tcaaaactcc atcttttgag     4920

cccaattatg tccattttgt tatagactaa atcaggggtt tgttctacaa gaacaataca     4980

tgttttaccc tttcctttaa ctagaaggat aactagtaat gcatcaacat aatttctgta     5040

ttaaccatca tgcgcacaag aaatacatag taaataagga agctgaaaac tcctggcatt     5100

ggatcttaag ctagatgatt agaatgtgaa aaagatttta caaatgtaaa acttctattt     5160

ctctgtagaa actttcttca ctttgctgtg caagaagaca ctgctttgct atatttaaaa     5220

tggctttttt aaaagagatt tatgtatttg gtaaatgttt gtagtcaaca gttcacacaa     5280

gaagctgtac acggtttgat catgtaaaac cgtttggcgg cacaagctgg actttgttgc     5340

catccttgag atgaaccttt taagaaaaat aagttaatct caatttttcc ctgaatgtgt     5400

tgtttttctt cattatacaa taaatataat agtgaacttt ttatcaaatg gtgaagacaa     5460

tgctaaaaaa aaaaaaaaaa a                                               5481


<210>  1477
<211>  5301
<212>  DNA
<213>  homo sapiens

<400>  1477
agaacgagtt ccggtctggc cgaggcttgt ctcctaaaaa tagccccggt gtggggatcc       60

gtgcgcggat gtcccggcga gtcccgggct gaaagaggcg gctccgggcg gcgcgaagcg      120

ctggtggcgg gcccgggctg cggcgtgtgc gcgcccgcca gctgctccgg agatacgatc      180

ttgtagaaaa tttcagctgt agcccttgga ctagaagctg aaataacaga agctgtgtac      240

gatgcattag ggtattgaag aaaattaact tttgaattaa atatttggaa tataaggaaa      300

taaggaaagt tgactgaaaa tggggcggaa gaaaatacaa atcacacgca taatggatga      360

aaggaaccga cagactttaa gaaagaaagg ccttaatggt tgtgagagcc ctgatgctga      420

cgattacttt gagcacagtc cactctcgga ggacagattc agcaaactaa atgaagatag      480

tgattttatt ttcaaacgag gccctcctgg tctgccacct cagaactttt caatgtctgt      540

cacagttcca gtgaccagcc ccaatgcttt gtcctacact aacccaggga gttcactggt      600

gtccccatct ttggcagcca gctcaacgtt aacagattca agcatgctct ctccacctca      660

aaccacatta catagaaatg tgtctcctgg agctcctcag agaccaccaa gtactggcaa      720

tgcaggtggg atgttgagca ctacagacct cacagtgcca aatggagctg gaagcagtcc      780

agtggggaat ggatttgtaa actcaagagc ttctccaaat ttgattggag ctactggtgc      840

aaatagctta ggcaaagtca tgcctacaaa gtctccccct ccaccaggtg gtggtaatct      900

tggaatgaac agtaggaaac cagatcttcg agttgtcatc cccccttcaa gcaagggcat      960

gatgcctcca ctatcggagg aagaggaatt ggagttgaat acccaaagga tcagtagttc     1020

tcaagccact caacctcttg ctaccccagt cgtgtctgtg acaaccccaa gcttgcctcc     1080

gcaaggactt gtgtactcag caatgccgac tgcctacaac actgattatt cactgaccag     1140

cgctgacctg tcagcccttc aaggcttcaa ctcgccagga atgctgtcgc tgggacaggt     1200

gtcggcctgg cagcagcacc acctaggaca agcagccctc agctctcttg ttgctggagg     1260

gcagttatct cagggttcca atttatccat taataccaac caaaacatca gcatcaagtc     1320

cgaaccgatt tcacctcctc gggatcgtat gaccccatcg ggcttccagc agcagcagca     1380

gcagcagcag cagcagcagc cgccgccacc accgcagccc cagccacaac ccccgcagcc     1440

ccagccccga caggaaatgg ggcgctcccc tgtggacagt ctgagcagct ctagtagctc     1500

ctatgatggc agtgatcggg aggatccacg gggcgacttc cattctccaa ttgtgcttgg     1560

ccgaccccca aacactgagg acagagaaag cccttctgta aagcgaatga ggatggacgc     1620

gtgggtgacc taaggcttcc aagctgatgt ttgtactttt gtgttactgc agtgacctgc     1680

cctacatatc taaatcggta aataaggaca tgagttaaat atatttatat gtacatacat     1740

atatatatcc ctttacatat atatgtatgt gggtgtgagt gtgtatgtgt gggtgtgtgt     1800

tacatacaca gaatcaggca cttacctgca aactccttgt aggtctgcag atgtgtgtcc     1860

catggcagac aaagcaccct gtaggcacag acaagtctgg cacttccttg gactacttgt     1920

ttcgtaaaga taaccagttt ttgcagagaa acgtgtaccc atatataatt ctcccacact     1980

agcttgcaga aacctagagg gccccctact tgttttattt aactgtgcag tgactgtagt     2040

tacttaagag aaaatgcttt gtagaacaga gcagtagaaa agcaggaacc aagaaagcaa     2100

tactgtacat aaaatgtcat ttatattttc caacctggca tgggtgtctg ttgcaaaggg     2160

gtgcatggga aagggctgtt gatattaaaa acaaacaaaa caaaaaagcc ccacacataa     2220

ctgttttgca cgtgcaaaaa tgtattgggt caagaagtga tctttagcta ataaagaaag     2280

agaatagaaa acacgcatga gatattcaga aaatactagc ctagaaatat agagcattaa     2340

caaagtaaaa ttaatatatt aagttataat tggaatatgt cagaagtttc tttttacatt     2400

catatcttaa aaattaaaga aactgatttt agctcatgta tattttatat gaaagaaaac     2460

acccttatga attgatgact atatataaaa ttatattcac tacttttgaa cacattctgc     2520

tatgaattat ttatataagc caaagctata tgttgtaact tttttttaga gaatagcttt     2580

atcttggttt aactctttag ttttatttta agaggggaaa acaaaaatat cttgcaagca     2640

gaaccttgga aaaaaaaagc catgaacact tattctaaat gtaaattaaa agttgagcca     2700

aactctttgt gtatatagca tcttaaatat attatcacct ttgatgtaag tacctatgta     2760

ttgtatggtc accagattaa aaagtatatt tttgtggatt gccgccaatc tggggggaaa     2820

aggcgaggtc ctttattaag tattcactgt ttaatattta ctattttgtt aaatatactg     2880

tactttggat tttaattatt agcccagttt tttcagagga ttgtataaag gggtttctcc     2940

cctcactggt ggtgaatgtg tgatgttaca ttgtaatctt tgtgctgtat gggttgagca     3000

tcattatata ttttgtatgt gtacataaat agcaaagtgg caaaaaaaat tggtgttaag     3060

ttcatcctgc ataagtataa aatgtgttgt aacagatttt gtaaggcatt atttaaaact     3120

tgccttttgt gaggaaaaaa tgtagtagaa aaagctgacc taatttaatt aatattagag     3180

aaaatggcaa aatagtagat gagcacaaag gttttataag tggtaaatga ttaggggaaa     3240

ataatcatgg ggaaagggat cttttttcct tgaccctctg aaaacagaac gatgcagctg     3300

gttacaaaat cctaccgtta tcagctcttc tgcacattgc agtgatgctt tggtatgcgg     3360

ggagaaacac tcttagggtg ctggtccttg gcatgactct tgccattcta attggaatta     3420

gtgccaccct cagcttggat tttgaacaag gccttattct ttcaggaaga caactaatgg     3480

atgatagcaa gttcatccac ttactgggct tgtgccatga gcaaaattca aagtcctgta     3540

tatctttcat tgtagatttt taaatactcc ttttcctaaa aaactcaagg gtttaaaaat     3600

tgctatttta tattttaaat gatattgagc agctacctac aatttctatg tacattttgt     3660

tccccccccc ccaccccccc cccaaattac gttccttttg acattttcct catctgctgt     3720

ttgtgacaag tcatcagcca gatttcctga ctgacacata ggtatgatca gtgcaggaga     3780

gacctgcgca ccacaggctg caaactggag gttctgttct catggcagtt tgggcagtaa     3840

cttttgagag aggccaaaaa aaggaggatg acatgctgtc tcctctcttc agtatagaca     3900

ttaggctctt attcagaaag gatttttctt taaaaatgta cttactttac tgaactactt     3960

acaggcacat ttcttcataa ggccacacct aatccaaaca agacagtctc ccaacactga     4020

agttccaaaa taatccttac cactttgtaa accatttata gctttgaaag tgttaagtga     4080

ttccttcgtt attatttatg catgttcatg aacttctgct gtacattgga ataggagtta     4140

acacattcac atttactgtc tattttcttg tgtgccttat gagatggctt ttctgactgt     4200

atctcaatag tctttctttc tatgcaggtt tataatcagt acaactactg ttttctaaaa     4260

tactactact caaggctcgg agtttgtatt taaattacac tgaccaagta acaatgtatt     4320

ccatttcagg aactgaatat ttgactgtta acctttttcc catacgtcca gtgtggcatg     4380

gagcatatgg acttgacaga catctctcac ccagacgccc acgtgtgaac acacccacat     4440

ccacatctct gggtggaaac cagcctagag aggggacgac gctaatggtg ttgctttaga     4500

accgtctttt cttacccttt tagactcgtg ttttgtatga gacaccattg caagaaaatt     4560

ttatccctcc agaagtattt tattactaaa gaacaaaagc aaaaaaagct taaattgcac     4620

tggttaaagt acagtttcca acagctgtcc ttcctcagta ctctaatggc cactccaccg     4680

cgagtggaag tcactgttgt gtgtacacag gtggtcccaa tcaaaactcc atcttttgag     4740

cccaattatg tccattttgt tatagactaa atcaggggtt tgttctacaa gaacaataca     4800

tgttttaccc tttcctttaa ctagaaggat aactagtaat gcatcaacat aatttctgta     4860

ttaaccatca tgcgcacaag aaatacatag taaataagga agctgaaaac tcctggcatt     4920

ggatcttaag ctagatgatt agaatgtgaa aaagatttta caaatgtaaa acttctattt     4980

ctctgtagaa actttcttca ctttgctgtg caagaagaca ctgctttgct atatttaaaa     5040

tggctttttt aaaagagatt tatgtatttg gtaaatgttt gtagtcaaca gttcacacaa     5100

gaagctgtac acggtttgat catgtaaaac cgtttggcgg cacaagctgg actttgttgc     5160

catccttgag atgaaccttt taagaaaaat aagttaatct caatttttcc ctgaatgtgt     5220

tgtttttctt cattatacaa taaatataat agtgaacttt ttatcaaatg gtgaagacaa     5280

tgctaaaaaa aaaaaaaaaa a                                               5301


<210>  1478
<211>  5100
<212>  DNA
<213>  homo sapiens

<400>  1478
atcttgtaga aaatttcagc tgtagccctt ggactagaag ctgaaataac agaagctgtg       60

tacgatgcat tagggtattg aagaaaatta acttttgaat taaatatttg gaatataagg      120

aaataaggaa agttgactga aaatggggcg gaagaaaata caaatcacac gcataatgga      180

tgaaaggaac cgacagactt taagaaagaa aggccttaat ggttgtgaga gccctgatgc      240

tgacgattac tttgagcaca gtccactctc ggaggacaga ttcagcaaac taaatgaaga      300

tagtgatttt attttcaaac gaggccctcc tggtctgcca cctcagaact tttcaatgtc      360

tgtcacagtt ccagtgacca gccccaatgc tttgtcctac actaacccag ggagttcact      420

ggtgtcccca tctttggcag ccagctcaac gttaacagat tcaagcatgc tctctccacc      480

tcaaaccaca ttacatagaa atgtgtctcc tggagctcct cagagaccac caagtactgg      540

caatgcaggt gggatgttga gcactacaga cctcacagtg ccaaatggag ctggaagcag      600

tccagtgggg aatggatttg taaactcaag agcttctcca aatttgattg gagctactgg      660

tgcaaatagc ttaggcaaag tcatgcctac aaagtctccc cctccaccag gtggtggtaa      720

tcttggaatg aacagtagga aaccagatct tcgagttgtc atcccccctt caagcaaggg      780

catgatgcct ccactaaata cccaaaggat cagtagttct caagccactc aacctcttgc      840

taccccagtc gtgtctgtga caaccccaag cttgcctccg caaggacttg tgtactcagc      900

aatgccgact gcctacaaca ctgattattc actgaccagc gctgacctgt cagcccttca      960

aggcttcaac tcgccaggaa tgctgtcgct gggacaggtg tcggcctggc agcagcacca     1020

cctaggacaa gcagccctca gctctcttgt tgctggaggg cagttatctc agggttccaa     1080

tttatccatt aataccaacc aaaacatcag catcaagtcc gaaccgattt cacctcctcg     1140

ggatcgtatg accccatcgg gcttccagca gcagcagcag cagcagcagc agcagcagcc     1200

gccgccacca ccgcagcccc agccacaacc cccgcagccc cagccccgac aggaaatggg     1260

gcgctcccct gtggacagtc tgagcagctc tagtagctcc tatgatggca gtgatcggga     1320

ggatccacgg ggcgacttcc attctccaat tgtgcttggc cgacccccaa acactgagga     1380

cagagaaagc ccttctgtaa agcgaatgag gatggacgcg tgggtgacct aaggcttcca     1440

agctgatgtt tgtacttttg tgttactgca gtgacctgcc ctacatatct aaatcggtaa     1500

ataaggacat gagttaaata tatttatatg tacatacata tatatatccc tttacatata     1560

tatgtatgtg ggtgtgagtg tgtatgtgtg ggtgtgtgtt acatacacag aatcaggcac     1620

ttacctgcaa actccttgta ggtctgcaga tgtgtgtccc atggcagaca aagcaccctg     1680

taggcacaga caagtctggc acttccttgg actacttgtt tcgtaaagat aaccagtttt     1740

tgcagagaaa cgtgtaccca tatataattc tcccacacta gcttgcagaa acctagaggg     1800

ccccctactt gttttattta actgtgcagt gactgtagtt acttaagaga aaatgctttg     1860

tagaacagag cagtagaaaa gcaggaacca agaaagcaat actgtacata aaatgtcatt     1920

tatattttcc aacctggcat gggtgtctgt tgcaaagggg tgcatgggaa agggctgttg     1980

atattaaaaa caaacaaaac aaaaaagccc cacacataac tgttttgcac gtgcaaaaat     2040

gtattgggtc aagaagtgat ctttagctaa taaagaaaga gaatagaaaa cacgcatgag     2100

atattcagaa aatactagcc tagaaatata gagcattaac aaagtaaaat taatatatta     2160

agttataatt ggaatatgtc agaagtttct ttttacattc atatcttaaa aattaaagaa     2220

actgatttta gctcatgtat attttatatg aaagaaaaca cccttatgaa ttgatgacta     2280

tatataaaat tatattcact acttttgaac acattctgct atgaattatt tatataagcc     2340

aaagctatat gttgtaactt ttttttagag aatagcttta tcttggttta actctttagt     2400

tttattttaa gaggggaaaa caaaaatatc ttgcaagcag aaccttggaa aaaaaaagcc     2460

atgaacactt attctaaatg taaattaaaa gttgagccaa actctttgtg tatatagcat     2520

cttaaatata ttatcacctt tgatgtaagt acctatgtat tgtatggtca ccagattaaa     2580

aagtatattt ttgtggattg ccgccaatct ggggggaaaa ggcgaggtcc tttattaagt     2640

attcactgtt taatatttac tattttgtta aatatactgt actttggatt ttaattatta     2700

gcccagtttt ttcagaggat tgtataaagg ggtttctccc ctcactggtg gtgaatgtgt     2760

gatgttacat tgtaatcttt gtgctgtatg ggttgagcat cattatatat tttgtatgtg     2820

tacataaata gcaaagtggc aaaaaaaatt ggtgttaagt tcatcctgca taagtataaa     2880

atgtgttgta acagattttg taaggcatta tttaaaactt gccttttgtg aggaaaaaat     2940

gtagtagaaa aagctgacct aatttaatta atattagaga aaatggcaaa atagtagatg     3000

agcacaaagg ttttataagt ggtaaatgat taggggaaaa taatcatggg gaaagggatc     3060

ttttttcctt gaccctctga aaacagaacg atgcagctgg ttacaaaatc ctaccgttat     3120

cagctcttct gcacattgca gtgatgcttt ggtatgcggg gagaaacact cttagggtgc     3180

tggtccttgg catgactctt gccattctaa ttggaattag tgccaccctc agcttggatt     3240

ttgaacaagg ccttattctt tcaggaagac aactaatgga tgatagcaag ttcatccact     3300

tactgggctt gtgccatgag caaaattcaa agtcctgtat atctttcatt gtagattttt     3360

aaatactcct tttcctaaaa aactcaaggg tttaaaaatt gctattttat attttaaatg     3420

atattgagca gctacctaca atttctatgt acattttgtt cccccccccc cacccccccc     3480

ccaaattacg ttccttttga cattttcctc atctgctgtt tgtgacaagt catcagccag     3540

atttcctgac tgacacatag gtatgatcag tgcaggagag acctgcgcac cacaggctgc     3600

aaactggagg ttctgttctc atggcagttt gggcagtaac ttttgagaga ggccaaaaaa     3660

aggaggatga catgctgtct cctctcttca gtatagacat taggctctta ttcagaaagg     3720

atttttcttt aaaaatgtac ttactttact gaactactta caggcacatt tcttcataag     3780

gccacaccta atccaaacaa gacagtctcc caacactgaa gttccaaaat aatccttacc     3840

actttgtaaa ccatttatag ctttgaaagt gttaagtgat tccttcgtta ttatttatgc     3900

atgttcatga acttctgctg tacattggaa taggagttaa cacattcaca tttactgtct     3960

attttcttgt gtgccttatg agatggcttt tctgactgta tctcaatagt ctttctttct     4020

atgcaggttt ataatcagta caactactgt tttctaaaat actactactc aaggctcgga     4080

gtttgtattt aaattacact gaccaagtaa caatgtattc catttcagga actgaatatt     4140

tgactgttaa cctttttccc atacgtccag tgtggcatgg agcatatgga cttgacagac     4200

atctctcacc cagacgccca cgtgtgaaca cacccacatc cacatctctg ggtggaaacc     4260

agcctagaga ggggacgacg ctaatggtgt tgctttagaa ccgtcttttc ttaccctttt     4320

agactcgtgt tttgtatgag acaccattgc aagaaaattt tatccctcca gaagtatttt     4380

attactaaag aacaaaagca aaaaaagctt aaattgcact ggttaaagta cagtttccaa     4440

cagctgtcct tcctcagtac tctaatggcc actccaccgc gagtggaagt cactgttgtg     4500

tgtacacagg tggtcccaat caaaactcca tcttttgagc ccaattatgt ccattttgtt     4560

atagactaaa tcaggggttt gttctacaag aacaatacat gttttaccct ttcctttaac     4620

tagaaggata actagtaatg catcaacata atttctgtat taaccatcat gcgcacaaga     4680

aatacatagt aaataaggaa gctgaaaact cctggcattg gatcttaagc tagatgatta     4740

gaatgtgaaa aagattttac aaatgtaaaa cttctatttc tctgtagaaa ctttcttcac     4800

tttgctgtgc aagaagacac tgctttgcta tatttaaaat ggctttttta aaagagattt     4860

atgtatttgg taaatgtttg tagtcaacag ttcacacaag aagctgtaca cggtttgatc     4920

atgtaaaacc gtttggcggc acaagctgga ctttgttgcc atccttgaga tgaacctttt     4980

aagaaaaata agttaatctc aatttttccc tgaatgtgtt gtttttcttc attatacaat     5040

aaatataata gtgaactttt tatcaaatgg tgaagacaat gctaaaaaaa aaaaaaaaaa     5100


<210>  1479
<211>  5771
<212>  DNA
<213>  homo sapiens

<400>  1479
agaacgagtt ccggtctggc cgaggcttgt ctcctaaaaa tagccccggt gtggggatcc       60

gtgcgcggat gtcccggcga gtcccgggct gaaagaggcg gctccgggcg gcgcgaagcg      120

ctggtggcgg gcccgggctg cggcgtgtgc gcgcccgcca gctgctccgg agatacggaa      180

ttgcattttg tgaaaaaaga acaagaattt tctgcaagga tcatatctaa gtgcactttt      240

tgctgatact tcatttctat ctcactctac cccccaggct gaagtgcagt ggtgtgatct      300

cggttcactg caacctccgc ctccaggttc aagtgattct cgtacctcag cctcccgagt      360

agctgggatt acaggcgcct gccaccatgc ctggctgata tttatatttt tagtagagat      420

ggagtttcac catgttggcc aggctggtct cgaactctgg acctcagatc ttgtagaaaa      480

tttcagctgt agcccttgga ctagaagctg aaataacaga agctgtgtac gatgcattag      540

ggtattgaag aaaattaact tttgaattaa atatttggaa tataaggaaa taaggaaagt      600

tgactgaaaa tggggcggaa gaaaatacaa atcacacgca taatggatga aaggaaccga      660

caggtcactt ttacaaagag aaagtttgga ttaatgaaga aagcctatga acttagtgtg      720

ctctgtgact gtgaaatagc actcatcatt ttcaacagct ctaacaaact gtttcaatat      780

gctagcactg atatggacaa agttcttctc aagtatacag aatataatga acctcatgaa      840

agcagaacca actcggatat tgttgagact ttaagaaaga aaggccttaa tggttgtgag      900

agccctgatg ctgacgatta ctttgagcac agtccactct cggaggacag attcagcaaa      960

ctaaatgaag atagtgattt tattttcaaa cgaggccctc ctggtctgcc acctcagaac     1020

ttttcaatgt ctgtcacagt tccagtgacc agccccaatg ctttgtccta cactaaccca     1080

gggagttcac tggtgtcccc atctttggca gccagctcaa cgttaacaga ttcaagcatg     1140

ctctctccac ctcaaaccac attacataga aatgtgtctc ctggagctcc tcagagacca     1200

ccaagtactg gcaatgcagg tgggatgttg agcactacag acctcacagt gccaaatgga     1260

gctggaagca gtccagtggg gaatggattt gtaaactcaa gagcttctcc aaatttgatt     1320

ggagctactg gtgcaaatag cttaggcaaa gtcatgccta caaagtctcc ccctccacca     1380

ggtggtggta atcttggaat gaacagtagg aaaccagatc ttcgagttgt catcccccct     1440

tcaagcaagg gcatgatgcc tccactaaat acccaaagga tcagtagttc tcaagccact     1500

caacctcttg ctaccccagt cgtgtctgtg acaaccccaa gcttgcctcc gcaaggactt     1560

gtgtactcag caatgccgac tgcctacaac actgattatt cactgaccag cgctgacctg     1620

tcagcccttc aaggcttcaa ctcgccagga atgctgtcgc tgggacaggt gtcggcctgg     1680

cagcagcacc acctaggaca agcagccctc agctctcttg ttgctggagg gcagttatct     1740

cagggttcca atttatccat taataccaac caaaacatca gcatcaagtc cgaaccgatt     1800

tcacctcctc gggatcgtat gaccccatcg ggcttccagc agcagcagca gcagcagcag     1860

cagcagcagc cgccgccacc accgcagccc cagccacaac ccccgcagcc ccagccccga     1920

caggaaatgg ggcgctcccc tgtggacagt ctgagcagct ctagtagctc ctatgatggc     1980

agtgatcggg aggatccacg gggcgacttc cattctccaa ttgtgcttgg ccgaccccca     2040

aacactgagg acagagaaag cccttctgta aagcgaatga ggatggacgc gtgggtgacc     2100

taaggcttcc aagctgatgt ttgtactttt gtgttactgc agtgacctgc cctacatatc     2160

taaatcggta aataaggaca tgagttaaat atatttatat gtacatacat atatatatcc     2220

ctttacatat atatgtatgt gggtgtgagt gtgtatgtgt gggtgtgtgt tacatacaca     2280

gaatcaggca cttacctgca aactccttgt aggtctgcag atgtgtgtcc catggcagac     2340

aaagcaccct gtaggcacag acaagtctgg cacttccttg gactacttgt ttcgtaaaga     2400

taaccagttt ttgcagagaa acgtgtaccc atatataatt ctcccacact agcttgcaga     2460

aacctagagg gccccctact tgttttattt aactgtgcag tgactgtagt tacttaagag     2520

aaaatgcttt gtagaacaga gcagtagaaa agcaggaacc aagaaagcaa tactgtacat     2580

aaaatgtcat ttatattttc caacctggca tgggtgtctg ttgcaaaggg gtgcatggga     2640

aagggctgtt gatattaaaa acaaacaaaa caaaaaagcc ccacacataa ctgttttgca     2700

cgtgcaaaaa tgtattgggt caagaagtga tctttagcta ataaagaaag agaatagaaa     2760

acacgcatga gatattcaga aaatactagc ctagaaatat agagcattaa caaagtaaaa     2820

ttaatatatt aagttataat tggaatatgt cagaagtttc tttttacatt catatcttaa     2880

aaattaaaga aactgatttt agctcatgta tattttatat gaaagaaaac acccttatga     2940

attgatgact atatataaaa ttatattcac tacttttgaa cacattctgc tatgaattat     3000

ttatataagc caaagctata tgttgtaact tttttttaga gaatagcttt atcttggttt     3060

aactctttag ttttatttta agaggggaaa acaaaaatat cttgcaagca gaaccttgga     3120

aaaaaaaagc catgaacact tattctaaat gtaaattaaa agttgagcca aactctttgt     3180

gtatatagca tcttaaatat attatcacct ttgatgtaag tacctatgta ttgtatggtc     3240

accagattaa aaagtatatt tttgtggatt gccgccaatc tggggggaaa aggcgaggtc     3300

ctttattaag tattcactgt ttaatattta ctattttgtt aaatatactg tactttggat     3360

tttaattatt agcccagttt tttcagagga ttgtataaag gggtttctcc cctcactggt     3420

ggtgaatgtg tgatgttaca ttgtaatctt tgtgctgtat gggttgagca tcattatata     3480

ttttgtatgt gtacataaat agcaaagtgg caaaaaaaat tggtgttaag ttcatcctgc     3540

ataagtataa aatgtgttgt aacagatttt gtaaggcatt atttaaaact tgccttttgt     3600

gaggaaaaaa tgtagtagaa aaagctgacc taatttaatt aatattagag aaaatggcaa     3660

aatagtagat gagcacaaag gttttataag tggtaaatga ttaggggaaa ataatcatgg     3720

ggaaagggat cttttttcct tgaccctctg aaaacagaac gatgcagctg gttacaaaat     3780

cctaccgtta tcagctcttc tgcacattgc agtgatgctt tggtatgcgg ggagaaacac     3840

tcttagggtg ctggtccttg gcatgactct tgccattcta attggaatta gtgccaccct     3900

cagcttggat tttgaacaag gccttattct ttcaggaaga caactaatgg atgatagcaa     3960

gttcatccac ttactgggct tgtgccatga gcaaaattca aagtcctgta tatctttcat     4020

tgtagatttt taaatactcc ttttcctaaa aaactcaagg gtttaaaaat tgctatttta     4080

tattttaaat gatattgagc agctacctac aatttctatg tacattttgt tccccccccc     4140

ccaccccccc cccaaattac gttccttttg acattttcct catctgctgt ttgtgacaag     4200

tcatcagcca gatttcctga ctgacacata ggtatgatca gtgcaggaga gacctgcgca     4260

ccacaggctg caaactggag gttctgttct catggcagtt tgggcagtaa cttttgagag     4320

aggccaaaaa aaggaggatg acatgctgtc tcctctcttc agtatagaca ttaggctctt     4380

attcagaaag gatttttctt taaaaatgta cttactttac tgaactactt acaggcacat     4440

ttcttcataa ggccacacct aatccaaaca agacagtctc ccaacactga agttccaaaa     4500

taatccttac cactttgtaa accatttata gctttgaaag tgttaagtga ttccttcgtt     4560

attatttatg catgttcatg aacttctgct gtacattgga ataggagtta acacattcac     4620

atttactgtc tattttcttg tgtgccttat gagatggctt ttctgactgt atctcaatag     4680

tctttctttc tatgcaggtt tataatcagt acaactactg ttttctaaaa tactactact     4740

caaggctcgg agtttgtatt taaattacac tgaccaagta acaatgtatt ccatttcagg     4800

aactgaatat ttgactgtta acctttttcc catacgtcca gtgtggcatg gagcatatgg     4860

acttgacaga catctctcac ccagacgccc acgtgtgaac acacccacat ccacatctct     4920

gggtggaaac cagcctagag aggggacgac gctaatggtg ttgctttaga accgtctttt     4980

cttacccttt tagactcgtg ttttgtatga gacaccattg caagaaaatt ttatccctcc     5040

agaagtattt tattactaaa gaacaaaagc aaaaaaagct taaattgcac tggttaaagt     5100

acagtttcca acagctgtcc ttcctcagta ctctaatggc cactccaccg cgagtggaag     5160

tcactgttgt gtgtacacag gtggtcccaa tcaaaactcc atcttttgag cccaattatg     5220

tccattttgt tatagactaa atcaggggtt tgttctacaa gaacaataca tgttttaccc     5280

tttcctttaa ctagaaggat aactagtaat gcatcaacat aatttctgta ttaaccatca     5340

tgcgcacaag aaatacatag taaataagga agctgaaaac tcctggcatt ggatcttaag     5400

ctagatgatt agaatgtgaa aaagatttta caaatgtaaa acttctattt ctctgtagaa     5460

actttcttca ctttgctgtg caagaagaca ctgctttgct atatttaaaa tggctttttt     5520

aaaagagatt tatgtatttg gtaaatgttt gtagtcaaca gttcacacaa gaagctgtac     5580

acggtttgat catgtaaaac cgtttggcgg cacaagctgg actttgttgc catccttgag     5640

atgaaccttt taagaaaaat aagttaatct caatttttcc ctgaatgtgt tgtttttctt     5700

cattatacaa taaatataat agtgaacttt ttatcaaatg gtgaagacaa tgctaaaaaa     5760

aaaaaaaaaa a                                                          5771


<210>  1480
<211>  1625
<212>  DNA
<213>  homo sapiens

<400>  1480
gttgccgggc tacgggagag cgcggagccc tgcgctggga ggtgcacggt gtgcacgctg       60

gactggaccc ccatgcaacc ccgcgccctg cgccttaacc aggactgctc cgcgcgcccc      120

tgagcctcgg gctccggccc ggacctgcag cctcccaggt ggctgggaag aactctccaa      180

caataaatac atttgataag aaagatggct ttaaaagtgc tactagaaca agagaaaacg      240

tttttcactc ttttagtatt actaggctat ttgtcatgta aagtgacttg tgaatcagga      300

gactgtagac agcaagaatt cagggatcgg tctggaaact gtgttccctg caaccagtgt      360

gggccaggca tggagttgtc taaggaatgt ggcttcggct atggggagga tgcacagtgt      420

gtgacgtgcc ggctgcacag gttcaaggag gactggggct tccagaaatg caagccctgt      480

ctggactgcg cagtggtgaa ccgctttcag aaggcaaatt gttcagccac cagtgatgcc      540

atctgcgggg actgcttgcc aggattttat aggaagacga aacttgtcgg ctttcaagac      600

atggagtgtg tgccttgtgg agaccctcct cctccttacg aaccgcactg tgccagcaag      660

gtcaacctcg tgaagatcgc gtccacggcc tccagcccac gggacacggc gctggctgcc      720

gttatctgca gcgctctggc caccgtcctg ctggccctgc tcatcctctg tgtcatctat      780

tgtaagagac agtttatgga gaagaaaccc agctggtctc tgcggtcaca ggacattcag      840

tacaacggct ctgagctgtc gtgttttgac agacctcagc tccacgaata tgcccacaga      900

gcctgctgcc agtgccgccg tgactcagtg cagacctgcg ggccggtgcg cttgctccca      960

tccatgtgct gtgaggaggc ctgcagcccc aacccggcga ctcttggttg tggggtgcat     1020

tctgcagcca gtcttcaggc aagaaacgca ggcccagccg gggagatggt gccgactttc     1080

ttcggatccc tcacgcagtc catctgtggc gagttttcag atgcctggcc tctgatgcag     1140

aatcccatgg gtggtgacaa catctctttt tgtgactctt atcctgaact cactggagaa     1200

gacattcatt ctctcaatcc agaacttgaa agctcaacgt ctttggattc aaatagcagt     1260

caagatttgg ttggtggggc tgttccagtc cagtctcatt ctgaaaactt tacagcagct     1320

actgatttat ctagatataa caacacactg gtagaatcag catcaactca ggatgcacta     1380

actatgagaa gccagctaga tcaggagagt ggtgctgtca tccacccagc cactcagacg     1440

tccctccagg taaggcagcg actgggttcc ctgtgaacac agcactgact tacagtagat     1500

cagaactctg ttcccagcat aagatttggg ggaacctgat gagttttttt tttgcatctt     1560

taataatttc ttgtatgttg tagagtatgt tttaaaataa atttcaagta tttttttaaa     1620

aaact                                                                 1625


<210>  1481
<211>  8482
<212>  DNA
<213>  homo sapiens

<400>  1481
gcgcgcagtg agaggcgccg gggctgccgc ccggtgctcg gcgcgctctc gggagccgcc       60

cgcccgctgg tcccgcagcc ttccgggagg aagcggtgcc ggcagcgtcc agggcgcgct      120

ctcgggcacc ctcacctgcc ggcgcccggc cgcttacccg gcagggcgtg cgcagggtag      180

ggtgcgggac cggggggacc tggaggcaga ggggagaacc ggccgtccgc gccgcagcac      240

agccgctggg agcgcctcag accccgcgcg gggcgccggc tccatggcga ccgggctcgg      300

ggagccggtc tatggacttt ccgaagacga gggagagtcc cgtattctca gagtaaaagt      360

tgtttctgga attgatctcg ccaaaaagga catctttgga gccagtgatc cgtatgtgaa      420

actttcattg tacgtagcgg atgagaatag agaacttgct ttggtccaga caaaaacaat      480

taaaaagaca ctgaacccaa aatggaatga agaattttat ttcagggtaa acccatctaa      540

tcacagactc ctatttgaag tatttgacga aaatagactg acacgagacg acttcctggg      600

ccaggtggac gtgcccctta gtcaccttcc gacagaagat ccaaccatgg agcgacccta      660

tacatttaag gactttctcc tcagaccaag aagtcataag tctcgagtta agggattttt      720

gcgattgaaa atggcctata tgccaaaaaa tggaggtcaa gatgaagaaa acagtgacca      780

gagggatgac atggagcatg gatgggaagt tgttgactca aatgactcgg cttctcagca      840

ccaagaggaa cttcctcctc ctcctctgcc tcccgggtgg gaagaaaaag tggacaattt      900

aggccgaact tactatgtca accacaacaa ccggaccact cagtggcaca gaccaagcct      960

gatggacgtg tcctcggagt cggacaataa catcagacag atcaaccagg aggcagcaca     1020

ccggcgcttc cgctcccgca ggcacatcag cgaagacttg gagcccgagc cctcggaggg     1080

cggggatgtc cccgagcctt gggagaccat ttcagaggaa gtgaatatcg ctggagactc     1140

tctcggtctg gctctgcccc caccaccggc ctccccagga tctcggacca gccctcagga     1200

gctgtcagag gaactaagca gaaggcttca gatcactcca gactccaatg gggaacagtt     1260

cagctctttg attcaaagag aaccctcctc aaggttgagg tcatgcagtg tcaccgacgc     1320

agttgcagaa cagggccatc taccaccgcc cagtgcccca gctgggagag cgcgttcatc     1380

aactgtcacg ggtggtgagg aaccaacgcc atcagtggcc tatgtacata ccacgccggg     1440

tctgccttca ggctgggaag aaagaaaaga tgctaagggg cgcacatact atgtcaatca     1500

taacaatcga accacaactt ggactcgacc tatcatgcag cttgcagaag atggtgcgtc     1560

cggatcagcc acaaacagta acaaccatct aatcgagcct cagatccgcc ggcctcgtag     1620

cctcagctcg ccaacagtaa ctttatctgc cccgctggag ggtgccaagg actcacccgt     1680

acgtcgggct gtgaaagaca ccctttccaa cccacagtcc ccacagccat caccttacaa     1740

ctcccccaaa ccacaacaca aagtcacaca gagcttcttg ccacccggct gggaaatgag     1800

gatagcgcca aacggccggc ccttcttcat tgatcataac acaaagacta caacctggga     1860

agatccacgt ttgaaatttc cagtacatat gcggtcaaag acatctttaa accccaatga     1920

ccttggcccc cttcctcctg gctgggaaga aagaattcac ttggatggcc gaacgtttta     1980

tattgatcat aatagcaaaa ttactcagtg ggaagaccca agactgcaga acccagctat     2040

tactggtccg gctgtccctt actccagaga atttaagcag aaatatgact acttcaggaa     2100

gaaattaaag aaacctgctg atatccccaa taggtttgaa atgaaacttc acagaaataa     2160

catatttgaa gagtcctatc ggagaattat gtccgtgaaa agaccagatg tcctaaaagc     2220

tagactgtgg attgagtttg aatcagagaa aggtcttgac tatgggggtg tggccagaga     2280

atggttcttc ttactgtcca aagagatgtt caacccctac tacggcctct ttgagtactc     2340

tgccacggac aactacaccc ttcagatcaa ccctaattca ggcctctgta atgaggatca     2400

tttgtcctac ttcactttta ttggaagagt tgctggtctg gccgtatttc atgggaagct     2460

cttagatggt ttcttcatta gaccatttta caagatgatg ttgggaaagc agataaccct     2520

gaatgacatg gaatctgtgg atagtgaata ttacaactct ttgaaatgga tcctggagaa     2580

tgaccctact gagctggacc tcatgttctg catagacgaa gaaaactttg gacagacata     2640

tcaagtggat ttgaagccca atgggtcaga aataatggtc acaaatgaaa acaaaaggga     2700

atatatcgac ttagtcatcc agtggagatt tgtgaacagg gtccagaagc agatgaacgc     2760

cttcttggag ggattcacag aactacttcc tattgatttg attaaaattt ttgatgaaaa     2820

tgagctggag ttgctcatgt gcggcctcgg tgatgtggat gtgaatgact ggagacagca     2880

ttctatttac aagaacggct actgcccaaa ccaccccgtc attcagtggt tctggaaggc     2940

tgtgctactc atggacgccg aaaagcgtat ccggttactg cagtttgtca cagggacatc     3000

gcgagtacct atgaatggat ttgccgaact ttatggttcc aatggtcctc agctgtttac     3060

aatagagcaa tggggcagtc ctgagaaact gcccagagct cacacatgct ttaatcgcct     3120

tgacttacct ccatatgaaa cctttgaaga tttacgagag aaacttctca tggccgtgga     3180

aaatgctcaa ggatttgaag gggtggatta agcaccctgt gcctcggggg tggttgttct     3240

tcaagcaagt tctgcttgca cttttgcatt tgcctaacag acttttgcag aggcgatggc     3300

agagagcagc tgcaggcatg gtccctggag ccgagccttc accacgcact cgtccaagtt     3360

cggatgcggg aacctggtcc cagcttgagt tcctgccttt cccaccacaa attatcaact     3420

ggttgatgtg tacactaatt acatttcagg aggacttaat gctatttatg ttgtgcctct     3480

gcaggcaaag cccttaataa atattttaca tcctttctaa tgacaatgaa tggaattaat     3540

cactcaacag gtatagtatt acgactcatg tttacttttt aaaatgattt agaccgattt     3600

tcagatttta tttcgttatg attaaagatg tctcatgtac ttggaaaagt gagcattttt     3660

tttttttttg tatttcactt tcataccagg cttaatgtca atgacatttt tatttttgaa     3720

gtactctgac acctccaccc tctactttat tagaattgga aggcaaattt ttgtccaaaa     3780

acctacagac aagtactttg agagaatttc caatataata ttagacataa tgataatttt     3840

ttccatactc agaatgaaaa actggatatt acgtttttgt tttggggttt ttttgtacaa     3900

atttagctaa tagctacagg ctgagagaat tgtaacatag catgacaaat tttgtgttga     3960

cttgaaagga atcacaccat tattccttag aagtaattac atgtgttcta acacatttga     4020

gacagggttg gactcccatt tctcatccga gaaattactt aacccttcct ggcgctgtac     4080

agtcatcttt tattctattt cctctttgct gtttgtagta gagacatttt gaatgaaact     4140

tggcactgct tgattcaaaa ctgtggaaac cagatctgtt tagtctcctg tttgtatgcg     4200

tttgctaatg gtagctaaat aaccagtttt tgttgtaaat gcaccaattc tgaaggcact     4260

ttatgtacta catggaggtc atatctggtt ttgtttttat ttttttatca tgaacattaa     4320

atgtgatgat gatttctttt ccctgcacac atctttccgg tgcaatatct atcaattgtg     4380

aatctggctg ctggtgtata aaaacctgga tgtaaagctg agcctacaga cctgtcctca     4440

ccaactgttt tgtgatttct actcaactac aaagatttat ttaatgtact cttaatctaa     4500

ctgagttttg ttaccaatga cctgttgcat gcttcaatac cgtgtactgc ctgagttgtg     4560

cctcttgtgt gctagattaa aagtgagaca gagacttgac ttgatcctct gagctcaagc     4620

tattgagctg gtagtggcag aggactgagg gtacctgcac agtttgattc ttttccacgt     4680

gtaagtctcc attgcagaat tgtcgtgctt tgagaaaaca cctgaggcag tgtgggagtt     4740

gaacgaccct gctgtccttt ttaacctgtg ttgtcctaga ccctgtcggg gcagtcaggg     4800

gacactagag atttgatctc atgcgagtca tcaataggac aaaaaagttg tggtttgggg     4860

aggtctgttt gttacataaa aaggaccttt cggtgtaaga aattgccgtt tttaccctgc     4920

cctggctggc atgtgagaag ccatggaagg ttgtggttgt aaatgagttg tctaaagggg     4980

tgcagaggcc tgaggtttct aaaagaaggt agatttctac agagctgagt gttggttcct     5040

ttttcttatt ggttgaaaat tacctggtag tgatcagaaa acttagatgc tatgtaacta     5100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaattcc cgctcatgag ttttgactat     5160

tggtgagatg ttttccgcta cagttaacat gacaaatgtc tcagtggcaa aaatcccctt     5220

tttgtaagcc cccatagtct agaggcagtt ttctttttaa gaatcatgcc agagcctgag     5280

tcgagcagta tgctttcttg gtttttgaga gtaattgtgt aattgtagag ggagaaatcc     5340

aattctaacc taagaactgg gattcttctg tcatcttgta aaccgtatat tgaaaaaaac     5400

agaatgtcac taaatgcata ttaagtcaag tattggaaag tataaaagaa aaatcattct     5460

gacaatttct aagccagaag caaacaagaa ttactgaaat ctaccccatg aatacttgga     5520

aggcagtaat tgtgagtgac acctcagttc atcaacccct taataatatc agcttaattt     5580

taatgacaac taaatatgct gaagtgagga tttagtattt tttaaaaaag caaaacaagg     5640

ttcagtagtc ctcagcaatt ctccaagttt ctctctttgc ctaaaatggt catagatctt     5700

gatttctctg aatcgtgatg accacaccca gtcatcttca cagcataatt gcaggtggca     5760

gtaaagagag tgtgctgggt aaggagcagt tgctgggtca ttccttgggc cccgacctgc     5820

ccggggagta gccctggggg agagagggca gtgttgccta tcccagaggt cccagcagtc     5880

acactgctct gcaggccggg ctctctttat agccagagaa atcaccttaa tgcagtctct     5940

ttagttgtct gctgaagctg tagttattat gggccactta catgaggctg agaagtacgt     6000

gccggagctc acacactgcc tgttgcggtt ctcttaacat cagttatcac agctgcctgt     6060

gggtcccggg tatttccatt cctgcccctt gttggcccga ggaaggatgt ggaaagagca     6120

cctggtggga tgaaggtcca acagcctgtg cctctccact gctggccctg gagccggcag     6180

cagtgaggca ttcattgtct gtgttgcggt gtattcccag cttcagtgct cttttccttt     6240

ttgcctgaaa tgtttatgct tctctgcagc cagtcctcta acaaatctca agaacaaagg     6300

taagacactt ggtttttgtt tccaggaccc ttcagaaggt gacatcagat attccctaaa     6360

ttcagacaat gagggataca gagcgacttg gcatgtatta tttctcccat gtaaggacaa     6420

agggacagat tattattgtt atttctgaga cagagtcttg ctctgtagct caggctggag     6480

tgcagtggct caatctcagc tcaccacaac ctctgcctcc tggcttcaag cgattcttct     6540

gcctcagcct ccccgaatag ttgggattac aggcacccac caccacgcct ggctaatttt     6600

tgtattttta gtagagatgg tttcaccatg ctggccaggc tggtcttgaa ctcctgacct     6660

caggtgatcc tcccgcctca gccttccaaa gtgctgggat tacaagcatg agccaccgca     6720

cccggcctca cagtgacaga ttctgagaaa cagcatgcaa aacatttgaa ccattttcta     6780

catctcccat tgttgcatag agagtgtgca ccgctgctat cttgccagat ccacactggt     6840

cctcccgaaa gccaggttca tacacagcaa ctttttaatt attctaacag ttacccatta     6900

acagtcgact cctgtatttc tgagagtctt gtactcacct ctgaaattta aaaacgtata     6960

aagagagcct gggttaatca gttctgcagc ccctacgtga cactgtgcta gttctccttc     7020

ttctgtctcc tccttaccct ggccctgcac ccctgtactt aagagggaga ggtgggaggt     7080

gctgtctggt atcatttgct gcctcgccag tagagggtgc cgctgtgcag ggtaactgcc     7140

cgcctgctcc cttcctgacc tcccctgacc ccgaagatca ctacctctgt cattcaggca     7200

ttggggtaca tcctgataag tcgtgtcaga actgccaatt tcaggactga gatgtgtttt     7260

taaaaaacaa atccttataa actccacttt gtactttaga ttttaaaact ggggaaaaat     7320

gtgatattct ttggaccact tttttaattt atataagcct taatgaacag tgtctataca     7380

tttgcataca cacaccccca ccccagagtg ttctcagtat gtcagagaaa gtgccacagc     7440

attaggacgg gagcttggag aacgttttct agaaaagggt tagcttcctg ttggcatgaa     7500

attttccaag caaacctcat taaacatctg ttgtttgtta aagatgttcc actgaaagca     7560

acgcatgttt caaaggcacg tctttccgtt cgttggtttt ctgtgtgtaa ggagtagcat     7620

tgctgttggc gcctaacctc gcgtgcactg cattctcaac cccgtaccag tgcatcatca     7680

gaagccttcc tcgtgaccat aactctgtgt ctgcagatat gtgttcccgt gtaagccagt     7740

tttccccttt tactcagact gatttcacct agattgtcac ggtttccttc atgttaactt     7800

tgcgtgactt tgttcttcct ttactactct gtatgtaata tatatacata tatacgtaca     7860

tatgctgtcc aaatatattt gtatatattt gtatagcatt tttacacctt tattgagtaa     7920

tctggtttcg aaaggaggtg agagtttagt cccttctgca gttttctcca agctgtgtcc     7980

tgtgaatttc aacccttgga gcctaagaaa accctaggaa gatgatgtta atttgctgtc     8040

atttcctaat tcaggatcta tcatcaaatg aaacatgaaa aaaacagtga cttttaaggt     8100

gaaaagagtt tcaagcattc caaataaatt atcaatgttt cataactttt tattataaac     8160

ccacctccta ataggaagcc aagtactatt tgatacagtg gtaaaaacca aactaccttg     8220

aattttttta aggcaactta tgaataatgc tcattttcac agtcagaata gctttaaaat     8280

atggttgaat ttgatacaca caggaagttt tcttgaagaa caatcctttc gcttttcttt     8340

tttcttgaga gatctaaaga gaaactgtag attgttttcc tgacagcaaa agactaatgt     8400

gacaaaatga agtcattgta aagaagcgat gcaacttgtc aaatatttaa taaagaatta     8460

tggaagctgg aacattttct ac                                              8482


<210>  1482
<211>  1788
<212>  DNA
<213>  homo sapiens

<400>  1482
gtacggcctg tccggcgctc gacgttccac ccccctctct ctgctctcag gttggttcag       60

cccccgtcta cactggggtg gtgcttagcc ggcgccagac cgaccctcga cttcggagag      120

gcagcgcggt tcctctgggt gcttccgcct ccccttctcc tgcttctcca gcctcttcgg      180

cctcctcgcc cgccgcggga acccgagacc ccagtgtatg ccccacccct gaccccgctc      240

gcgacatgtc caccccggct cggcggcgcc tcatgcggga cttcaagagg ttgcaggagg      300

atcctccagc cggagtcagc ggggctccgt ccgagaacaa cataatggtg tggaacgcgg      360

tcattttcgg gcctgaaggg accccgtttg aggatgtcta tgcagatggt agtatatgtc      420

tggacatact tcagaaccgt tggagtccaa cctatgatgt gtcttccatt ctaacatcca      480

tacagtctct gttggatgaa cccaatccca atagtccagc aaacagccag gctgctcagc      540

tgtaccagga gaacaaacgg gaatatgaaa agcgtgtttc tgcaatagta gaacaaagct      600

ggcgtgattg ttgaccccgg gtacagttta aagaagctgg ccataagaaa aatatatatt      660

gatgtgtttg tcacctccct actcctgtca ttacatttac tttattaaaa gcaaaataac      720

tgttgtgctg tttccatctt ccttgccaag ttttcctacc ccttctaccc tctccttaaa      780

catcagaaaa caccctctat gaaatcaaat gtactgtacc tgggttactt gcaaaaatta      840

ctaatgcttc agtttttctg ttgtatttca tttccagttt tcaggcagtt atttttatta      900

ttgtacttta agcttttaag atgaattgtt atacaagagg tgcttatgct tagcttgatg      960

accaggatgt tatttttaac aaaatgattg ctgaagtgtt tcatcctggc tggtccttca     1020

cttgtgttgg atttagaagt gaatgtgttt ggaatatggc ctacagagaa tagaaacaaa     1080

tccatgtaaa caattttgaa ggaggcatgg gagctaaaaa tcctgtgata ctaagatctc     1140

agtcatatga attacaacgt agtatttact ggcaagaagg agaaagttga aggactcagc     1200

taaaggagta cagcaattgt agtaactgac acatcctctc tttgcaagct gctgactggg     1260

cacactcatg ccaagtttca gaattattgg tcttctgggt ttttgctttt taaaagaggt     1320

gtgggagcag aggaatggaa acaatcgtga gtttttgagc tagggaaagt tggagctcct     1380

ttaatctttt taaaggatca gtgctgccct aagtgaataa actcaattgt ccatctttat     1440

tttagagttt taatgaattc aaggaaggga gcatagcata tctgtggcaa actattttcc     1500

actcaaatcc tgagttattg ctgcatgctt taatttcttc cctttcagca tctgagaacc     1560

ttaaagccaa tgtctgcgat ctttttttgg atatttatac ttttagatat atagtacctt     1620

taagtagcag tatgggacaa ggcttgtaaa tgttttgtct aatgttctat tgtcaccttt     1680

tatgcattta tcacttccaa atctaacttt gcacaagtaa cccatgtaaa aaaaaatgta     1740

catttttcaa aagttgtaaa taaaaataac cttaaaattt catagtca                  1788


<210>  1483
<211>  2019
<212>  DNA
<213>  homo sapiens

<400>  1483
agggcttcgg gcccccgggg ccagccgccg tcctgcgaac gcgcggcgcc cgggccgctg       60

cccccttccg gccccgcggc ggccccgcct cctcccccga cttccttccc tgagcacggc      120

ggcggcgggg acgagcaccg gcctgcgcgc ggagccggca ccggatgacc caacatgagt      180

gaagtttcct gcaagaaacg ggacgactat ttggaatggc cagagtattt tatggctgtg      240

gccttcttat cagcacagag aagcaaagat ccaaattccc aggtcggcgc ctgcatcgtg      300

aattcagaaa acaagattgt cgggattggg tacaatggga tgccaaatgg gtgcagtgat      360

gacgtgttgc cttggagaag gacagcagag aataagctgg acaccaaata cccgtacgtg      420

tgccatgcgg agctgaatgc catcatgaac aaaaattcga ccgatgtgaa aggctgtagt      480

atgtatgttg ccttgttccc ttgtaatgaa tgcgctaagc tcatcatcca ggcaggtata      540

aaagaagtga ttttcatgtc tgataaatac catgatagtg acgaggcaac tgctgcgagg      600

ctcctgttta atatggccgg ggtgacattc cggaaattca taccgaagtg cagcaagatt      660

gtcattgact ttgattcaat taacagcaga ccgagtcaaa agcttcagtg agttacatct      720

cattcaatct ccagaagatt gggattatcg tcttctaaga ggttgctaat gcctttcatc      780

ttgaagttac acataacttc ttactagcca gtatggcaaa agtaggcatc taaagaatat      840

aaagcctcaa atcttcctta ctgtctctct tgtcacatgg aatctacatg tgtttgaact      900

attgctttag ggtttaaaat aggggagcct gtggtggcct ggtgcacagg gctagaacga      960

gagtgcctcc ccttcttgtg tcctggctgg ctgggatgct ggtggctctt cagaggagca     1020

tcagctgtct gtcatctgct gcgatccggc agcctctctt cactgctaca tgtgctggaa     1080

ggacaaataa ataattgtgg ttgtgttctt aatggggacg agcagacaca ctgatctgaa     1140

catctggccc aagtgaagca tggcatatag tgcccttgga agaaaattag gcctcaaatg     1200

acagtagcat tgaagtgttt gctgcagagt tgagggaaac ccccagccac cctcccggaa     1260

tccgagatag ggtggcacat ctgtcctgac agacgaggag tgtaactgaa ccaggaatat     1320

ttcctccatt cctgctctcc cactgcacac agggtggtgg cacattatcc ctctgggggg     1380

tggggacgcc tgttgttttg gctcaatttg ggtttgttgg tcacatggag ctcttccatt     1440

tcgtttagct gaataatgag ttgttcctag aggagacagc ctgtctctcc ttgttgcccc     1500

caaagcccat gccctgccgt ggtggcagct ggggctgtgg atgggagggg tccccaacat     1560

ggatgtgttg cccctcctcc gcatgccaac gcagttcatg tacaaggccc ctctgcaact     1620

ggagagaaaa ttaattccta tcccgtgagt ggattgtgag aaattccacc cacgtggaga     1680

cagcttactg cagcactgtt ggtgttcgga gctcttctgt gccctggctc catgctttca     1740

cctacacaag catcaccttc ctaatcaccg cggggcgggg agcgtgtggc tgtgcccctt     1800

ctctttaatc tcatttaatt tttattaaac atgctcagta cctgtgttga gaaaaggctt     1860

tctttatcct aaagattatt acctttttaa agtgctctta tattttcatg agtttttatt     1920

ttgtctctga gattttgtat tccacattct agggtattct gtaatttggc tccttaccaa     1980

tattattaaa atcttattaa aatctaccct accaaagca                            2019


<210>  1484
<211>  2042
<212>  DNA
<213>  homo sapiens

<400>  1484
agggcttcgg gcccccgggg ccagccgccg tcctgcgaac gcgcggcgcc cgggccgctg       60

cccccttccg gccccgcggc ggccccgcct cctcccccga cttccttccc tgagcacggc      120

ggcggcgggg acgagcaccg gcctgcgcgc ggagccggca ccggatggtg ggcgggggcc      180

agccgtgcgg acccaacatg agtgaagttt cctgcaagaa acgggacgac tatttggaat      240

ggccagagta ttttatggct gtggccttct tatcagcaca gagaagcaaa gatccaaatt      300

cccaggtcgg cgcctgcatc gtgaattcag aaaacaagat tgtcgggatt gggtacaatg      360

ggatgccaaa tgggtgcagt gatgacgtgt tgccttggag aaggacagca gagaataagc      420

tggacaccaa atacccgtac gtgtgccatg cggagctgaa tgccatcatg aacaaaaatt      480

cgaccgatgt gaaaggctgt agtatgtatg ttgccttgtt cccttgtaat gaatgcgcta      540

agctcatcat ccaggcaggt ataaaagaag tgattttcat gtctgataaa taccatgata      600

gtgacgaggc aactgctgcg aggctcctgt ttaatatggc cggggtgaca ttccggaaat      660

tcataccgaa gtgcagcaag attgtcattg actttgattc aattaacagc agaccgagtc      720

aaaagcttca gtgagttaca tctcattcaa tctccagaag attgggatta tcgtcttcta      780

agaggttgct aatgcctttc atcttgaagt tacacataac ttcttactag ccagtatggc      840

aaaagtaggc atctaaagaa tataaagcct caaatcttcc ttactgtctc tcttgtcaca      900

tggaatctac atgtgtttga actattgctt tagggtttaa aataggggag cctgtggtgg      960

cctggtgcac agggctagaa cgagagtgcc tccccttctt gtgtcctggc tggctgggat     1020

gctggtggct cttcagagga gcatcagctg tctgtcatct gctgcgatcc ggcagcctct     1080

cttcactgct acatgtgctg gaaggacaaa taaataattg tggttgtgtt cttaatgggg     1140

acgagcagac acactgatct gaacatctgg cccaagtgaa gcatggcata tagtgccctt     1200

ggaagaaaat taggcctcaa atgacagtag cattgaagtg tttgctgcag agttgaggga     1260

aacccccagc caccctcccg gaatccgaga tagggtggca catctgtcct gacagacgag     1320

gagtgtaact gaaccaggaa tatttcctcc attcctgctc tcccactgca cacagggtgg     1380

tggcacatta tccctctggg gggtggggac gcctgttgtt ttggctcaat ttgggtttgt     1440

tggtcacatg gagctcttcc atttcgttta gctgaataat gagttgttcc tagaggagac     1500

agcctgtctc tccttgttgc ccccaaagcc catgccctgc cgtggtggca gctggggctg     1560

tggatgggag gggtccccaa catggatgtg ttgcccctcc tccgcatgcc aacgcagttc     1620

atgtacaagg cccctctgca actggagaga aaattaattc ctatcccgtg agtggattgt     1680

gagaaattcc acccacgtgg agacagctta ctgcagcact gttggtgttc ggagctcttc     1740

tgtgccctgg ctccatgctt tcacctacac aagcatcacc ttcctaatca ccgcggggcg     1800

gggagcgtgt ggctgtgccc cttctcttta atctcattta atttttatta aacatgctca     1860

gtacctgtgt tgagaaaagg ctttctttat cctaaagatt attacctttt taaagtgctc     1920

ttatattttc atgagttttt attttgtctc tgagattttg tattccacat tctagggtat     1980

tctgtaattt ggctccttac caatattatt aaaatcttat taaaatctac cctaccaaag     2040

ca                                                                    2042


<210>  1485
<211>  8994
<212>  DNA
<213>  homo sapiens

<400>  1485
accatagagt gaatctcaga acaggaagcg gaggcataag cagagaggat tctggaaagg       60

tctctttgtt ttcttatcca cagagaaaga aagaaaaaaa attgtaacta atttgtaaac      120

ctctgtggtc aaaaaaaaaa aaaaaaaaaa aagctgaaca gctgcagagg aagacacgtt      180

ataccctaac catcttggat gctgggcttt gttatgctgt aattcataag gctctgtttt      240

atcagagatt atggagcaag aaaactgaag ccaagccaca tcaaggtttg acagggatga      300

gatacctgtc aaggattcat agtagagtgg cttactggga aaggagcaaa gaatctcttc      360

tagggatatt gtaagaataa atgagataat tcacagaagg gacctggagc ttttccggaa      420

aaaggtgctg tgactatcta aggtaattcg tatgcaagaa gctacacgta attaaatgtg      480

caggatgaaa agatggcaca ggcactgttg gtacccccag gacctgaaag cttccgcctt      540

tttactagag aatctcttgc tgctatcgaa aaacgtgctg cagaagagaa agccaagaag      600

cccaaaaagg aacaagataa tgatgatgag aacaaaccaa agccaaatag tgacttggaa      660

gctggaaaga accttccatt tatttatgga gacattcctc cagagatggt gtcagagccc      720

ctggaggacc tggatcccta ctatatcaat aagaaaactt ttatagtaat gaataaagga      780

aaggcaattt tccgattcag tgccacctct gccttgtata ttttaactcc actaaaccct      840

gttaggaaaa ttgctatcaa gattttggta cattctttat tcagcatgct tatcatgtgc      900

actattttga ccaactgtgt atttatgacc ttgagcaacc ctcctgactg gacaaagaat      960

gtagagtaca cattcactgg aatctatacc tttgagtcac ttataaaaat cttggcaaga     1020

gggttttgct tagaagattt tacgtttctt cgtgatccat ggaactggct ggatttcagt     1080

gtcattgtga tggcgtatgt aacagaattt gtaagcctag gcaatgtttc agcccttcga     1140

actttcagag tcttgagagc tctgaaaact atttctgtaa ttccaggttt aaagaccatt     1200

gtgggggccc tgatccagtc ggtaaagaag ctttctgatg tgatgatcct gactgtgttc     1260

tgtctgagcg tgtttgctct cattgggctg cagctgttca tgggcaatct gaggaataaa     1320

tgtttgcagt ggcccccaag cgattctgct tttgaaacca acaccacttc ctactttaat     1380

ggcacaatgg attcaaatgg gacatttgtt aatgtaacaa tgagcacatt taactggaag     1440

gattacattg gagatgacag tcacttttat gttttggatg ggcaaaaaga ccctttactc     1500

tgtggaaatg gctcagatgc aggccagtgt ccagaaggat acatctgtgt gaaggctggt     1560

cgaaacccca actatggcta cacaagcttt gacaccttta gctgggcttt cctgtctcta     1620

tttcgactca tgactcaaga ctactgggaa aatctttacc agttgacatt acgtgctgct     1680

gggaaaacat acatgatatt ttttgtcctg gtcattttct tgggctcatt ttatttggtg     1740

aatttgatcc tggctgtggt ggccatggcc tatgaggagc agaatcaggc caccttggaa     1800

gaagcagaac aaaaagaggc cgaatttcag cagatgctcg aacagcttaa aaagcaacag     1860

gaagaagctc aggcagttgc ggcagcatca gctgcttcaa gagatttcag tggaataggt     1920

gggttaggag agctgttgga aagttcttca gaagcatcaa agttgagttc caaaagtgct     1980

aaagaatgga ggaaccgaag gaagaaaaga agacagagag agcaccttga aggaaacaac     2040

aaaggagaga gagacagctt tcccaaatcc gaatctgaag acagcgtcaa aagaagcagc     2100

ttccttttct ccatggatgg aaacagactg accagtgaca aaaaattctg ctcccctcat     2160

cagtctctct tgagtatccg tggctccctg ttttccccaa gacgcaatag caaaacaagc     2220

attttcagtt tcagaggtcg ggcaaaggat gttggatctg aaaatgactt tgctgatgat     2280

gaacacagca catttgaaga cagcgaaagc aggagagact cactgtttgt gccgcacaga     2340

catggagagc gacgcaacag taacggcacc accacagaaa cggaagtcag aaagagaagg     2400

ttaagctctt accagatttc aatggagatg ctggaggatt cctctggaag gcaaagagcc     2460

gtgagcatag ccagcattct gaccaacaca atggaagaac ttgaagaatc tagacagaaa     2520

tgtccgccat gctggtatag atttgccaat gtgttcttga tctgggactg ctgtgatgca     2580

tggttaaaag taaaacatct tgtgaattta attgttatgg atccatttgt tgatcttgcc     2640

atcactattt gcattgtctt aaataccctc tttatggcca tggagcacta ccccatgact     2700

gagcaattca gtagtgtgtt gactgtagga aacctggtct ttactgggat tttcacagca     2760

gaaatggttc tcaagatcat tgccatggat ccttattact atttccaaga aggctggaat     2820

atctttgatg gaattattgt cagcctcagt ttaatggagc ttggtctgtc aaatgtggag     2880

ggattgtctg tactgcgatc attcagactg cttagagttt tcaagttggc aaaatcctgg     2940

cccacactaa atatgctaat taagatcatt ggcaattctg tgggggctct aggaaacctc     3000

accttggtgt tggccatcat cgtcttcatt tttgctgtgg tcggcatgca gctctttggt     3060

aagagctaca aagaatgtgt ctgcaagatc aatgatgact gtacgctccc acggtggcac     3120

atgaacgact tcttccactc cttcctgatt gtgttccgcg tgctgtgtgg agagtggata     3180

gagaccatgt gggactgtat ggaggtcgct ggccaaacca tgtgccttat tgttttcatg     3240

ttggtcatgg tcattggaaa ccttgtggtt ctgaacctct ttctggcctt attgttgagt     3300

tcatttagct cagacaacct tgctgctact gatgatgaca atgaaatgaa taatctgcag     3360

attgcagtag gaagaatgca aaagggaatt gattatgtga aaaataagat gcgggagtgt     3420

ttccaaaaag ccttttttag aaagccaaaa gttatagaaa tccatgaagg caataagata     3480

gacagctgca tgtccaataa tactggaatt gaaataagca aagagcttaa ttatcttaga     3540

gatgggaatg gaaccaccag tggtgtaggt actggaagca gtgttgaaaa atacgtaatc     3600

gatgaaaatg attatatgtc attcataaac aaccccagcc tcaccgtcac agtgccaatt     3660

gctgttggag agtctgactt tgaaaactta aatactgaag agttcagcag tgagtcagaa     3720

ctagaagaaa gcaaagagaa attaaatgca accagctcat ctgaaggaag cacagttgat     3780

gttgttctac cccgagaagg tgaacaagct gaaactgaac ccgaagaaga ccttaaaccg     3840

gaagcttgtt ttactgaagg atgtattaaa aagtttccat tctgtcaagt aagtacagaa     3900

gaaggcaaag ggaagatctg gtggaatctt cgaaaaacct gctacagtat tgttgagcac     3960

aactggtttg agactttcat tgtgttcatg atccttctca gtagtggtgc attggccttt     4020

gaagatatat acattgaaca gcgaaagact atcaaaacca tgctagaata tgctgacaaa     4080

gtctttacct atatattcat tctggaaatg cttctcaaat gggttgctta tggatttcaa     4140

acatatttca ctaatgcctg gtgctggcta gatttcttga tcgttgatgt ttctttggtt     4200

agcctggtag ccaatgctct tggctactca gaactcggtg ccatcaaatc attacggaca     4260

ttaagagctt taagacctct aagagcctta tcccggtttg aaggcatgag ggtggttgtg     4320

aatgctcttg ttggagcaat tccctctatc atgaatgtgc tgttggtctg tctcatcttc     4380

tggttgatct ttagcatcat gggtgtgaat ttgtttgctg gcaagttcta ccactgtgtt     4440

aacatgacaa cgggtaacat gtttgacatt agtgatgtta acaatttgag tgactgtcag     4500

gctcttggca agcaagctcg gtggaaaaac gtgaaagtaa actttgataa tgttggcgct     4560

ggctatcttg cactgcttca agtggccaca tttaaaggct ggatggatat tatgtatgca     4620

gctgttgatt cacgagatgt taaacttcag cctgtatatg aagaaaatct gtacatgtat     4680

ttatactttg tcatctttat catctttggg tcattcttca ctctgaatct attcattggt     4740

gtcatcatag ataacttcaa ccagcagaaa aagaagtttg gaggtcaaga catctttatg     4800

acagaggaac agaaaaaata ttacaatgca atgaagaaac ttggatccaa gaaacctcag     4860

aaacccatac ctcgcccagc aaacaaattc caaggaatgg tctttgattt tgtaaccaga     4920

caagtctttg atatcagcat catgatcctc atctgcctca acatggtcac catgatggtg     4980

gaaacggatg accagggcaa atacatgacc ctagttttgt cccggatcaa cctagtgttc     5040

attgttctgt tcactggaga atttgtgctg aagctcgtct ccctcagaca ctactacttc     5100

actataggct ggaacatctt tgactttgtg gtggtgattc tctccattgt aggtatgttt     5160

ctggctgaga tgatagaaaa gtattttgtg tcccctacct tgttccgagt gatccgtctt     5220

gccaggattg gccgaatcct acgtctgatc aaaggagcaa aggggatccg cacgctgctc     5280

tttgctttga tgatgtccct tcctgcgttg tttaacatcg gcctcctgct cttcctggtc     5340

atgtttatct atgccatctt tgggatgtcc aactttgcct atgttaaaaa ggaagctgga     5400

attgatgaca tgttcaactt tgagaccttt ggcaacagca tgatctgctt gttccaaatt     5460

acaacctctg ctggctggga tggattgcta gcacctattc ttaatagtgc accacccgac     5520

tgtgaccctg acacaattca ccctggcagc tcagttaagg gagactgtgg gaacccatct     5580

gttgggattt tcttttttgt cagttacatc atcatatcct tcctggttgt ggtgaacatg     5640

tacatcgcgg tcatcctgga gaacttcagt gttgctactg aagaaagtgc agagcccctg     5700

agtgaggatg actttgagat gttctatgag gtttgggaaa agtttgatcc cgatgcgacc     5760

cagtttatag agttctctaa actctctgat tttgcagctg ccctggatcc tcctcttctc     5820

atagcaaaac ccaacaaagt ccagcttatt gccatggatc tgcccatggt cagtggtgac     5880

cggatccact gtcttgatat tttatttgcc tttacaaagc gtgttttggg tgagagtgga     5940

gagatggatg cccttcgaat acagatggaa gacaggttta tggcatcaaa cccctccaaa     6000

gtctcttatg agcctattac aaccactttg aaacgtaaac aagaggaggt gtctgccgct     6060

atcattcagc gtaatttcag atgttatctt ttaaagcaaa ggttaaaaaa tatatcaagt     6120

aactataaca aagaggcaat taaagggagg attgacttac ctataaaaca agacatgatt     6180

attgacaaac taaatgggaa ctccactcca gaaaaaacag atgggagttc ctctaccacc     6240

tctcctcctt cctatgatag tgtaacaaaa ccagacaagg aaaagtttga gaaagacaaa     6300

ccagaaaaag aaagcaaagg aaaagaggtc agagaaaatc aaaagtaaaa agaaacaaag     6360

aattatcttt gtgatcaatt gtttacagcc tatgaaggta aagtatatgt gtcaactgga     6420

cttcaagagg aggtccatgc caaactgact gttttaacaa atactcatag tcagtgccta     6480

tacaagacag tgaagtgacc tctctgtcac tgcaactctg tgaagcaggg tatcaacatt     6540

gacaagaggt tgctgttttt attaccagct gacactgctg aggagaaacc caatggctac     6600

ctagactata gggatagttg tgcaaagtga acattgtaac tacaccaaac acctttagta     6660

cagtccttgc atccattcta tttttaactt ccatatctgc catattttta caaaatttgt     6720

tctagtgcat ttccatggtc cccaattcat agtttattca taatgctatg tcactatttt     6780

tgtaaatgag gtttacgttg aagaaacagt atacaagaac cctgtctctc aaatgatcag     6840

acaaaggtgt tttgccagag agataaaatt tttgctcaaa accagaaaaa gaattgtaat     6900

ggctacagtt tcagttactt ccattttcta gatggcttta attttgaaag tattttagtc     6960

tgttatgttt gtttctatct gaacagttat gtgcctgtaa agtctcctct aatatttaaa     7020

ggattatttt tatgcaaagt attctgtttc agcaagtgca aattttattc taagtttcag     7080

agctctatat ttaatttagg tcaaatgctt tccaaaaagt aatctaataa atccattcta     7140

gaaaaatata tctaaagtat tgctttagaa tagttgttcc actttctgct gcagtattgc     7200

tttgccatct tctgctctca gcaaagctga tagtctatgt caattaaata ccctatgtta     7260

tgtaaatagt tattttatcc tgtggtgcat gtttgggcaa atatatatat agcctgataa     7320

acaacttcta ttaaatcaaa tatgtaccac agtgtatgtg tcttttgcaa gcttccaaca     7380

gggatgtatc ctgtatcatt cattaaacat agtttaaagg ctatcactaa tgcatgttaa     7440

tattgcctat gctgctctat tttactcaat ccattcttca caagtcttgg ttaaagaatg     7500

tcacatattg gtgatagaat gaattcaacc tgctctgtcc attatgtcaa gcagaataat     7560

ttgaagctat ttacaaacac ctttactttt gcacttttaa ttcaacatga gtatcatatg     7620

gtatctctct agatttcaag gaaacacact ggatactgcc tactgacaaa acctattctt     7680

catattttgc taaaaatatg tctaaaactt gtttaaatat aaataatgta aaaatataat     7740

caactttatt tgtcagcatt ttgtacataa gaaaattatt ttcaggttga tgacatcaca     7800

atttatttta ctttatgctt ttgcttttga tttttaatca caattccaaa cttttgaatc     7860

cataagattt ttcaatggat aatttcctaa aataaaagtt agataatggg ttttatggat     7920

ttctttgtta taatatattt tctaccattc caataggaga tacattggtc aaacactcaa     7980

acctagatca ttttctacca actatggttg cctcaatata accttttatt catagatgtt     8040

tttttttatt caacttttgt agtatttacg tatgcagact agtcttattt ttttaattcc     8100

tgctgcacta aagctattac aaatataaca tggactttgt tctttttagc catgaacaaa     8160

gtggcaaagt tgtgcaatta cctaacatga tataaatttt tgttttttgc acaaaccaaa     8220

agtttaatgt taattctttt tacaaaacta tttactgtag tgtattgaag aactgcatgc     8280

agggaattgc tattgctaaa aagaatggtg agctacgtca ttattgagcc aaaagaataa     8340

atttcatttt ttattgcatt tcacttattg gcctctgggg ttttttgttt ttgttttttg     8400

ctgttggcag tttaaaatat atataattaa taaaacctgt gcttgatctg acatttgtat     8460

acataaaagt ttacatgaat tttacaacaa actagtgcat gattcaccaa gcagtactac     8520

agaacaaagg caaattaaaa gcagctttgt gaacttttat gtgtgcaaag gatcaagttc     8580

acatgttcca actttcaggt ttgataataa tagtagtaac cacctacaat agctttcaat     8640

ttcaattaac tcccttggct ataagcatct aaactcatct tctttcaata taattgatgc     8700

tatctcctaa ttacttggtg gctaataaat gttacattct ttgttactta aatgcattat     8760

ataaactcct atgtatacat aaggtattaa tgatatagtt attgagaatt tatattaact     8820

tttttttcaa gaacccttgg atttatgtga ggtcaaaacc aaactcttat tctcagtgga     8880

aaactccagt tgtaatgcat atttttaaag acaatttgga tctaaatatg tatttcataa     8940

ttctcccata ataaattata taaggtggct aattggaaaa aaaaaaaaaa aaaa           8994


<210>  1486
<211>  8228
<212>  DNA
<213>  homo sapiens

<400>  1486
ccgcgggtct atgggaagtt cggggacttg acagccgctg ccgccgcagg gcatttttgg       60

tcgaagagag ctgaagtaat gagaagacat catggaggcc cagtcccaca gctccacgac      120

cactgaaaag aaaaaagttg agaattccat agtgaagtgc tccactcgaa cagatgtgag      180

cgagaaagcc gttgcctcca gcaccacttc taatgaggat gaaagtcctg gacagactta      240

tcacagagag agaagaaacg caatcactat gcagccacag aatgtccagg ggctcagcaa      300

agtcagtgag gaaccttcaa catcgagtga cgagagggcc tcattgatca agaaagagat      360

ccatgggtcc ctgccacacg tggcggagcc ctctgtgccg taccgcggga cggtgtttgc      420

catggacccc aggaatggtt acatggagcc ccactaccac cctcctcatc ttttccctgc      480

cttccatcct cctgtaccaa ttgatgccag acatcatgag ggccgttacc attacgatcc      540

atctccgatt cctccattgc atatgacttc cgccttatct agtagcccta cgtatccgga      600

cctgcccttc attaggatct ccccacaccg gaaccccact gctgcttccg agtctccctt      660

cagccctcca catccctaca ttaatcccta catggactat atccgctcct tgcacagcag      720

cccatcgctc tccatgatct cagcaacccg tgggctgagc cctacagatg cgccccatgc      780

aggagtcagc ccagcagaat actatcatca gatggccctg ctaactggcc agcgcagccc      840

ctatgcagac attattccct cagctgccac cgccggcacg ggggccatcc acatggaata      900

tcttcatgct atggatagca ccagattctc cagccccagg ctgtcagcca ggccgagccg      960

aaaacgtaca ctgtccatat caccactctc cgatcatagc tttgaccttc agaccatgat     1020

aaggacgtct cccaactcct tggtcacgat tctcaataat tcccgtagca gctcttcagc     1080

aagtggctcc tatggtcact tatctgcaag tgcaatcagc cctgccttga gcttcaccta     1140

ctcttccgcg cccgtctctc tccacatgca tcagcagatc ctaagccgac aacagagctt     1200

aggttcagcc tttggacaca gccctccact catccaccct gccccaactt ttccaacaca     1260

gaggcctatt ccagggatcc ctacggttct gaaccccgtc caggtcagct ccggcccttc     1320

tgagtcctca cagaacaagc ccacgagtga gtctgcagtg agcagcactg gtgacccgat     1380

gcacaacaag aggtccaaga tcaaacccga tgaagacctc cccagcccag gggctcgggg     1440

gcagcaggaa cagcccgaag gaacaaccct tgtcaaggag gaaggggaca aagatgaaag     1500

caaacaggag cctgaagtca tctatgagac aaactgccac tgggaaggct gcgcgaggga     1560

gttcgacacc caagagcagc ttgtgcacca tataaataac gaccatattc atggagagaa     1620

gaaggagttc gtgtgcaggt ggctggactg ctcaagagag cagaaaccct tcaaagccca     1680

gtatatgttg gtagtgcata tgagaagaca cacgggcgag aagcctcaca aatgcacttt     1740

tgaaggttgc acaaaggcct actcgagact agaaaacttg aaaacacact tgagatctca     1800

cactggagag aaaccatacg tctgtgagca cgaaggttgc aacaaggctt tctcaaatgc     1860

ctctgatcgc gccaaacacc aaaacagaac gcattccaat gagaaaccat atgtgtgcaa     1920

aatcccaggc tgcactaagc gttacacaga cccaagctcc ctccggaaac atgtgaagac     1980

agtgcatggc ccagaggctc atgtcaccaa gaagcagcga ggggacatcc atcctcggcc     2040

gccacccccg agagattccg gcagccattc acagtccagg tcgcctggcc gaccgactca     2100

gggagccctt ggtgagcagc aggacctcag caacactacc tcaaagcggg aagaatgcct     2160

ccaggtgaaa accgtcaagg cagagaagcc aatgacatct cagccaagcc ctggtggtca     2220

gtcttcatgc agcagccaac agtcccccat cagcaactat tccaacagtg ggctcgagct     2280

tcctctgacc gatggaggta gtataggaga cctcagtgcc atcgatgaaa ccccaatcat     2340

ggactcaacc atttccactg caaccacagc ccttgctttg caagccagga gaaacccggc     2400

agggaccaaa tggatggagc acgtaaaact agaaaggcta aaacaagtga atggaatgtt     2460

tccgcgactg aaccccattc taccccctaa agcccctgcg gtctctcctc tcataggaaa     2520

tggcacacag tccaacaaca cctgcagctt gggtgggccc atgacgcttc tcccgggcag     2580

aagcgacctc tctggggtgg acgtcactat gctgaacatg ctcaacagaa gggacagcag     2640

cgccagcacc atcagctcgg cctacctgag cagccgccgc tcctcaggga tctcgccctg     2700

cttctccagc cgccgctcca gcgaggcgtc acaggccgag ggccggccgc agaacgtgag     2760

cgtggccgac tcctacgacc ccatctccac cgacgcctcg cgccgctcca gcgaagccag     2820

ccagagcgac ggcctgccca gcctgctcag cctcacgccc gcccagcagt accgcctcaa     2880

ggccaagtac gcggctgcca caggagggcc gccgccgacg cccctgccca acatggagag     2940

gatgagcctg aagacgcgcc tggcgctgct cggggatgcc ctcgagcctg gcgtggccct     3000

gcctccagtt catgccccga ggaggtgcag cgacggggga gcccacggct acgggcggcg     3060

ccacctgcag ccgcacgatg cgccgggcca cggcgtgagg agggccagcg acccggtgcg     3120

gacaggctcc gagggcctgg ccctgcctcg tgtgccgcgc ttcagcagcc tcagcagctg     3180

caaccccccg gcgatggcca cgtccgcgga gaagcgcagt ctcgtgcttc agaattacac     3240

gcggcccgag ggcggccagt cccgaaactt ccactcgtcc ccctgtcctc ccagcatcac     3300

cgagaacgtc accctggagt ccctgaccat ggacgctgat gccaacctga acgatgagga     3360

tttcctgccg gacgacgtgg tgcagtattt aaattcccag aaccaagcag ggtacgagca     3420

gcacttcccc agcgccctcc cggacgacag caaagtgccc cacgggcccg gtgactttga     3480

cgcgcccggg ctgccagaca gccacgctgg ccagcagttc catgccctcg agcagccctg     3540

ccccgagggc agcaaaaccg acctgcccat tcagtggaac gaagtcagct ccggaagcgc     3600

cgacctgtcc tcctccaagc tcaagtgtgg gccgcggccc gctgtgccgc agactcgcgc     3660

ctttgggttc tgcaacggca tggtcgtcca cccgcagaac cccttgagga gcgggcctgc     3720

tgggggctat cagaccctcg gggagaacag caacccctac ggtggcccag agcacttgat     3780

gctccacaac agccccggaa gtggcaccag tggaaacgcc ttccatgaac agccctgtaa     3840

ggccccgcag tatgggaact gtctcaacag gcagccagtg gcccctggtg cactcgacgg     3900

tgcctgtggt gccgggattc aagcctcaaa gctgaagagc acccccatgc aagggagcgg     3960

gggccagctg aatttcggcc tgccggtagc gccaaatgag tcagctggca gcatggtgaa     4020

tggcatgcag aaccaggacc cagtgggaca ggggtacctg gctcaccagc tcctcggcga     4080

cagcatgcag cacccggggg caggccgccc cggtcagcag atgcttgggc agattagtgc     4140

tacctcacac atcaacatct accaagggcc agagagctgc ctgccagggg ctcacggcat     4200

gggcagccag ccgtcaagct tggcagttgt caggggctac cagccatgtg ccagctttgg     4260

gggcagcagg cgccaggcta tgccgaggga cagccttgct ctgcagtcag gacagctcag     4320

tgacacaagt cagacctgca gggtgaatgg tatcaagatg gagatgaaag ggcagcccca     4380

tccgctgtgc tctaatctgc agaattactc tggtcagttc tatgaccaaa ccgtgggctt     4440

cagtcagcaa gacacgaaag ctggttcatt ctctatttca gacgccagct gcctgctaca     4500

ggggaccagc gccaaaaact ctgagttact ttccccaggt gctaatcagg tgacaagcac     4560

agtggacagc ctcgacagcc atgacctgga aggggtacag attgacttcg atgccatcat     4620

agacgatggg gaccactcca gcctgatgtc gggggccctg agcccaagta tcattcagaa     4680

cctttcccat agctcctccc gcctcaccac gcctcgggcg tccctcccat tcccagcgct     4740

gtccatgagc accaccaaca tggctatcgg ggacatgagt tctttgctga cctccctagc     4800

ggaagaaagc aaattccttg cagttatgca ataggcttta ggaaaaaaag actgcaacca     4860

acggaaatca ataggagttg aagagattaa actgactttg ttttggctgt ttttttagtt     4920

ctgtatgtat tttagcaatc tcatctcacc taactgagat gtgtttcaat tatattcctt     4980

ttatggaaaa ggactctgaa aaaccctaaa gtattctagg gagaaactgt cttccatttc     5040

agttttgaat cagtattgtt acactcaaac caccctcttt ttaaaaaaaa aaaaaaaaac     5100

tgtaagcccc gccccctttt tagtaaaccg atgtaaattt gtgatgtgca tattcttctt     5160

tcttttagaa gagcagtcaa attaaaggat ttgacatgtt ttgctgttgc tcaaaggaaa     5220

taggagttgg tgtgcttgtg accaaggggt tacacttcca gcttttaaaa ttctccttta     5280

catgtgctca gtgttttgtt ttgtgttttg gtttctgttt tttattttaa ttcccacatt     5340

gggcacaaga atcagaatat ggatagctag tttaagaaac ttttgtgggt gcactgtagc     5400

atagatgaca gaatattgat gttcccccca tctccaattc agttcagggc attccacagt     5460

taaacagaaa tgggaacgtg gggctcttat aaatgaaatg ggcgctcaca gttttggttt     5520

tcagctcttc atgtctgtaa gtgtgctttg ggggaggcta tgtctgtatg gtcgattctc     5580

agttatcaca tttgcctctc ctcccactac cttcatgaac attcagtgct gtttcgcact     5640

gcagttagag agaagggacg gacagttggt gacactcagc cacattgcta cttttatctg     5700

ttctggtaag aagttagata gatggtagat tgaagcaatt gggtagaatt agttggggga     5760

atatttatga gttgctgtgt ttgttgatta gttccatctc tttcccattt taactgagaa     5820

ttgattatat atagctctaa gtatataggt atttaaacaa ccccacaagc ggctgtatca     5880

gtaacattta ttaattccac tatagtgagg gaggatttcc attctaaata ccttattttg     5940

agggatttat aaaacttagt tgtaaaagag aaagcccaca tagtgggaat aaattgcttc     6000

agccattttt agtatttgag agcactaggg aagatgttta gtagctgtgt ggatgccttt     6060

tttcacaccc tgtctattga atgctgcatc cattcacgaa gttaaatgtt acatgcagtt     6120

agtccttaat gtggactgga tctgtacttt tgttttggat taaaacattt aaagattttt     6180

gaagtgcagc tactccccac gtgcatttga tacacataaa agtcatactg tgtgtgcaca     6240

aagagtacat ggattttcca gcatattgct ttaaaaaatt atataaactg ttaaaatatt     6300

aacacctcag gctacctgct gtattctgtc ccattgaccc ctggaattgg atttactgca     6360

agtgattgat aattcaatta tgtggctttt cccctttaat cttgccattt aaattacagt     6420

agaaagacaa aatcaagtaa aataaagtgt tagataatag aaagagtgtt aagaccagcc     6480

cacttttctc atgtttatgt tctttcattt ggaccaagaa tctccgcatg gaggttgatt     6540

tgccactggg gactttggct aagactatta ggtttgcttt caactagatg ttcctgagac     6600

aagcagaggg acactgcaat tccccttcca tgcctgctgt tctcccccat gtaagtcttc     6660

tttgaaatta acggatgtgt ctcctttgga acagccccat aacaaaagag aactactgat     6720

ctgagcatag gaaagtagag gctctaccac ttttcagttg aaaaagcaag actttctctg     6780

tgtttctgaa acaaggcata atgttgtcac agaatcagag atccagtctc acttttccac     6840

aaatctccaa atctccagtc ttatcttgtg tgctctaatg gtttggttca atccctttcc     6900

aactcttgtt ttcaaagcat ggggcctgag tgttctccac tcctcctaag aaaggagctt     6960

gggtggaagg gaccatgctg acctcctcca tcagagggct cttccagtag tattctcgga     7020

tgcaacctcc atttctcagt taccattatt tcctgtatca gctttgtcct tcctggaggg     7080

atgcacagtg atccggccca ccactgttgt tgtcttgtgc ttctgctctt tcctatggtt     7140

tcaggttatt ttctgggttt cccctattct tcttttattt cttttttttt ttatatttgc     7200

tttcctttct actgctttta gatttgcagg agatgcaagt ttcagctcaa tgtttggctt     7260

ctctcaatat ggaaatttca gaaggacaga ggagaggagg gaggaagaag aaagtatact     7320

cctccagaat ttcagtgatc tgttgtggca gtccagtgga aggaaggtct tttgaggtca     7380

cttagaagca tctttttggg acatcctttt gggatctctg taggctaggc atctcatatc     7440

ttgagactca cccccagcct ccaagcctct ctccatttct ctaacctatg cattttagag     7500

cgagaggacc gcctcactag tgtcaccatc ctgccttttc taaaacatgc aggctcacac     7560

attctactcc tgcttaatgt ctgtgttaaa cgttttctaa ccatttttgt tttatttttc     7620

tgaaaaagtt aacccctccc aactcctcac acattggctc ttcctcttga gccacaaagt     7680

tttgattctt gcgatgtatg tgccttattt tatgttaatc ttgtcaatga gagggaccag     7740

ttggtgttgc ccaatcagca ctccaaggct gtgtgtgcac cagccagaga gcgcacggtg     7800

gtagcagagt cgaggctgtc ttgtatcctg gtttcatgtg ttgttttgaa ctgataggag     7860

gatgttctct tctgacaagt tacccttgtg tatcctgcag acatgtaaaa taaaatacaa     7920

gttcattttt ttcacctttt ttagattttt ttaaaaaata aaatgtgtaa tccttttttt     7980

aaaagaaaca catgtaaata catttaagta ttgtaggcat agcgttcaga tgtgactggc     8040

ccaggcgttc ctcggacaag cctgcattcc ccgtgatcac gcccacctca agcccagggg     8100

ctgcagccca gccacagatg aactctacct ttgctttcag aaccacttag tccttttgta     8160

acaaagaaaa aaaaatgttt cttacaatgt caataaaaaa ttctttgtat ggaaaaaaaa     8220

aaaaaaaa                                                              8228


<210>  1487
<211>  6672
<212>  DNA
<213>  homo sapiens

<400>  1487
atcctttatg gttgaagggt gttggaggaa gcagagtttt catcagctgc tgaagtggca       60

actaatagag gtttgaatgg ccgtagaaaa atattgtgtt acttgtttgt tgtctagggg      120

ctcttggctt tgggcctcag tgcaagtcca ttggaaaagg cagctgcaac aatctagtgg      180

tcaccagcag tcccatgatg gttcagcgac tgggactcat ttcacctcca gcaagccagg      240

tctctacagc atgcaaccag atcagtccta gcttacagag ggcaatgaat gcagccaacc      300

tgaatatacc tccttcagat accaggtccc ttatttcgcg tgagtctttg gcgtccacga      360

ccttgagtct gacggaaagt cagtcggcct caagcatgaa gcaggagtgg tcccagggct      420

acagggccct cccttcgctc tccaaccacg gctctcagaa tggccttgat ctaggggatc      480

tccttagcct tcctcccggg acatccatgt ccagcaatag tgtctctaac tcattaccat      540

cctacctttt tggcacggaa agtagccact ctccttaccc tagtcctcgg cactcatcca      600

ccaggtccca ctcggcccgc tccaagaaga gagcgctgtc cttgtccccg ctgtccgatg      660

gcatcgggat agatttcaat accatcatcc gcacgtcgcc cacgtccttg gtggcctaca      720

tcaacgggtc gagggcttcg ccggccaacc tgtccccgca gccggaggtc tacgggcatt      780

tcctgggcgt gcgcggcagc tgcattcccc agccgcgccc ggtgcccggc agccagaagg      840

gcgtgctggt ggcccctgga ggcctggcgc tgccggccta cggcgaggac ggggccctgg      900

agcacgagcg catgcaacag ctggagcacg gcggcctgca gccaggcctg gtcaaccaca      960

tggtggtgca gcatggcctg ccgggccccg acagccagtc ggccggcctg ttcaagaccg     1020

aacgcctgga ggagttcccg ggcagcaccg tagacctacc ccccgcgcct ccgctccctc     1080

ctctgccgcc gcccccaggc cccccacccc cttaccatgc ccatgcgcac cttcaccacc     1140

cggagctcgg gccccacgcc cagcagctgg ccttgcccca ggccaccctg gacgacgacg     1200

gggagatgga cggcatcggg ggcaagcatt gctgccgctg gatcgactgc agcgccctgt     1260

acgaccagca ggaggagctc gtgcggcaca tcgagaaggt ccacatcgac cagcgcaaag     1320

gggaggactt cacttgcttc tgggccggtt gccctcgaag atacaagccc ttcaacgccc     1380

gctataaact gctgatccac atgagagtcc actctgggga gaagcccaac aagtgtacgt     1440

ttgaaggttg cgagaaggcc ttttcaaggc ttgaaaatct caagatccac ttgcggagcc     1500

acacaggcga gaagccgtat ttgtgccagc atccgggttg tcagaaggcc ttcagtaact     1560

ccagtgaccg cgccaaacac cagcggacgc atctggacac caaaccttat gcttgtcaaa     1620

ttccaggatg taccaaacgc tacacagacc caagttccct aagaaagcat gtgaaggcac     1680

attcttccaa agagcaacaa gcaaggaaaa agttgcggtc cagcacagag ctccatccag     1740

acctgctcac agattgcctc accgtgcagt ccctgcagcc ggccacttcc cctagagatg     1800

ctgctgctga agggaccgtg ggacgctccc ctggacccgg gcctgacctc tattcagctc     1860

ccattttctc cagcaattat tcaagccgaa gtggaacagc tgctggggcc gtaccacccc     1920

cacatcctgt cagtcaccct tctccaggac ataatgtaca ggggagccct cacaacccct     1980

cctcccagtt acctccactc acagctgtgg acgcaggagc tgagaggttt gcaccttctg     2040

ctccatctcc tcaccacatc agcccccgga gagttccagc tccttcttca atactgcaaa     2100

gaacacagcc tccctatacc cagcagccat caggttcaca cctgaagtcc tatcagccag     2160

aaacaaactc ttcttttcaa ccaaatggta tccatgtcca tggattttat gggcagctgc     2220

agaagttctg tcccccacac taccccgatt cccagagaat tgtgccgcct gtcagctcct     2280

gcagtgtggt gccttcgttt gaggactgcc tagtccctac atccatgggc caggccagtt     2340

ttgatgtttt ccacagagcc ttctcgactc actcgggcat tacagtgtat gatttacctt     2400

caagttcctc gagcctcttt ggggagtctc tccgcagcgg ggctgaagat gctaccttct     2460

tgcagatcag caccgtggac cgctgtccta gccagctctc ctctgtctac accgaaggct     2520

aaaagctctc ttggccactc ctgcacaccc aggaccttga tgttgcttgc caccttttgt     2580

tttcgtactc tcacagactg cttgaggaag gatgtcagcc caatcagcgg gccctgcaga     2640

gttactgatg ttctttcaga aggcaggact gaatggcaga gctagctttg caggaatcat     2700

tacagttgct cctttttctc tctggttttc ctggactatg tgaccaggag gactgtcttt     2760

tcaaagggaa tttagagcct cactctcctg gatacctgtt acttcctggc tgtcaaccct     2820

taaaggaccc cagtgaaatg atgtgcatat gaaaatgtag tttggggatg actctacctg     2880

aaaactccaa acagggaaaa agacctcaat tacgagaggc atagtgacct gcctcaccta     2940

atcctcaccc ttgctgctcc tgatgcaaag ccaggcacaa caagggaaat ccatgtccaa     3000

agcatagtgt ggtctcaact cttagaaact ccctgggttt cccttttctc ttagccacat     3060

gctaaccagt tgcttctcag tgtttctctt caatagaaaa ataaggtttt atatgccagc     3120

agcctatcct tgtttttgca ttttaaagac ttagttattt atacgtattt taaaatgaaa     3180

aaaaaatgta aaggtctgtg ctttggatgg aaatcattat tattgtaatc accccagcta     3240

tagacatttt gcacagctgt ggttctgcct ggccccacct ctagcatgtt agttttgcag     3300

ttagcaaagg ttacctgagg gaaatggagt gggcacctcc cgcaccaaca gtcctgtagc     3360

tggaaccttc ctgagttgac tgtttagtaa ctccacctca aagactgtgt tcaaagaaaa     3420

atgttgtttg actggtttac ccattgcctc cactctggtg ctgcacccag agaagtgcca     3480

gatgtgagaa ctgggacaga ctgagtcatg tgccagcttc ccttggaaaa ccaaacctag     3540

tgatacttga cttccagtgc tcagatttta ctaacgtttt tcaggatatc cactcatctg     3600

tctgtctctt ccctacactt ctctccaccc tctttttgca tccctcttac cctcttcctg     3660

actgtggttc atatatcccc accagccgcc attgtctgat catcttggga aggtagaggt     3720

gacagttctc gaaaagtcta cagaaagagg caattctttt tctgagttcc agtttgaagg     3780

cctggaattt tcacatagca cttggtcgaa aatatcaagc ctaaatagga agtcattttc     3840

tgtgacacct ctacatagct attacagatc ctaagtccta gggcatcagc tataaaaatt     3900

ggccagtccc aaagacacag taagttctaa cattctggta ctatcatatt tcaagtattt     3960

tttctcactt tttaaaaatg tttttctgaa caaaagtgaa acaatgccat ttatcaaact     4020

gagatcatta caatcttcaa caagacaact aaaacagctt gatgttagat gggattctgt     4080

gacagtttgt atactgacag gtccttccag tctccctcca cagtcccaca agcggaagta     4140

ttctacctga ttccagagtt cattccaaca tgcagtagaa tgaggtgaat gaagaaccaa     4200

gtgtgggttt tgttttcaca gtgcacttgg tcaatctagt ttctctgagt agtgggctgt     4260

attctaagaa aagctttcac gtagacgtca aagtctgcaa aagagatgag ttagccactt     4320

taaaaaacct gctctgcttt acaaaagatg cacaccaggc ttcctttaca agtgaactcc     4380

aaggctgctt gtaaagtacc acccttcctg cagactttgt gggtcgtgtc acttggccta     4440

aacaagtggc ctaacatatg catgctcaca gctagtagca tccctcatgc gtcctttgtc     4500

atactctgga aagaaaaaaa ctctgctatc ttcagagaaa ccatctattc atacttaaat     4560

atggaagcct ttacaaggaa ctcaaaatac atttcatttc atttgtacaa tgagaaaaaa     4620

gatgaaaagg caaggttgtt attgcagttg acattgtcag ccctgccttt tggctttatg     4680

taatttaaaa tagaaagggg gaaggaggac aagacagaag ctcaacttta gaaaccatgg     4740

acatcacctc cctctttgag aggagctgct tgtgaaccag gctccagtct tcctgtggcc     4800

tctcacagta accctgcccc tttcttacct cacaggggca agagggactc taaagagggc     4860

gtaagcaata gaggcacctg cagccctcct tcctcagcag gaaatcaatg tggagcccca     4920

gagggacatt ttatctcaga gagagcatgc tggccacagg acccagtgca gccctgcttc     4980

ccgcaccgtg ggtctttcct gatagctgca ggcttgagat tgcagcctca ggataggaca     5040

cgttcagatg ccttccagac tacacacact atgcttagat tcgagagtct ttcctgacct     5100

taaaatttgt cccttgctta ctttcacact gcagaagatt tatatatata ttcatcatta     5160

tttttgcagc agtacaagtg gaaacttcaa aaaaatcatt ccctttcatg tcctggtctt     5220

tttaagtctt gatatgtaac cattttcata aatgtccaaa cagagattgt cattcccctt     5280

aaaaacagaa acaaaacaca aaactagtgc ttgtgaaaac acacagcgca aagacaatta     5340

tcctattgca ttaaaaaaaa aatcagtctg cctagagaca tttcattggc tgcattgtct     5400

taattcccta acgaaactgc atcaaaatgt cagttgtaat ttagcctctg atcagctgtt     5460

aaatattatt taaatattta caggtcctgt ggggtatctc ccattaccca tgtcgccctc     5520

aaattacata agcgatcata aaataagaag aaaaaaaaag gtctttagta gatcacagca     5580

gagttaccac tgataagagt gttggctttg ttcagttgtt tctaaattac cagccgtcaa     5640

gcacagtagc ccctaaaacc aattttgagc aaggataaat tcaactccct catctgagaa     5700

ccttgacttt ccagttgcct tgaagtattg ggaatagtaa ctgtacattt tcaatttaat     5760

tatttggtat tttatttgac tgtcttggcc atgtcatttt atggaagcat ttttaaatag     5820

cactttttgt tagtggtgtg gaatttctgc ggttattatt tttttttttt tttgcaacag     5880

atgaagcaaa aaaaaaaaag cactcattgg agaaatagtg agtgtaaaaa gagatttatt     5940

ttgtacagac agcaaagtat cctgtgtaat gttgctgaca taaagcactt tgggggaaaa     6000

aagtggaaat ctgttttcca taaatcacac agactcttgt acatagttat atacactcac     6060

gtagagaaat gaactgcata tatcatactg gatatggggc cgattttact ctagaggcac     6120

atctggtgct tattgtcata aatcttttaa agaattaggt acactttttt ctattaatat     6180

gtatagtttt gtgatttgtc acagttatgt ttcatataat cataagttat tttgtcttgt     6240

tcatgaagtc ctttttttat gtcaaaagta aaatgaaggg attgtgcact tggtacagaa     6300

taaaactgga aatagagaag acgccctcct gcctaaaatc ctccttcagc ctgtcggttt     6360

aaaacacaat ggcaaccatc attgtttgtt tgtttgtttt tttgttttgt tttaccatca     6420

gcctcttaca tactgggaat ggtaattata attaaaggca gatgatgcgg gagggaatgt     6480

tcaagtccag ctttaaaatg ctgcattgct ttgggccaga gctgtagcct ggatttaatt     6540

atagatatga ggaggaaatg gcagtaaaaa tgaatgtctc cctgagtcct ttacatgttg     6600

ggagtgtcca taaataaaac atgaagtttt atttcatcag atttaattaa agcttttata     6660

catgttaaaa aa                                                         6672


<210>  1488
<211>  7656
<212>  DNA
<213>  homo sapiens

<400>  1488
ctccctccct cttccccctt cccctctccc tgcagccgcg tccacactgc gccgcccggg       60

cagcccagag cgcggcgcgc acgggcaccg gcggcgagtg ccgcggccac tgcccctccc      120

gggaccccct gtacgccgtc cgcgccgtcc agggtcacac cggcgacgga acccgccggc      180

agcaattagc cagcatcccg gggtcggccc ccagaagcat tccccggccc aggacgagga      240

tgaacaggac aggcgaggca caaagtcgca actgaacttt ttagaaacat tatttgtgtg      300

tgtatgtgtg tagcagggga gaatgagctg atgccgaggg tccagccacc ccgcctctgc      360

ctcctcctcc ccctgccgcc gctgccctcg cagacgcgcg cgcacacacg gcacttgggc      420

cgggtttccg cgctccgtcc ccccgtttgg atgggggttt tcatttccga aggaggcaca      480

gcccgcggag cgctctgaag ggctggagcc ccaagttact cctcgccagc gccggccgcc      540

cgctgtcact cgcgctggcc ggccggggga agggacccgc acgccgggct ttgttgtgga      600

aatcccggtt acctggctta taacccacac catggataac ttattggact ttgcctgaaa      660

ggagtcatta gtgacattgg atatttgacc gtcttggcca caggtttttc agaatgaatg      720

gaagatcatg cagcatgagt ctccaccgga catcgggaac cccacagggg cctaggatgg      780

tcagtggtca tcacattcct gccatccgag cccactccgg gactcctggc ccctcgccct      840

gtggcagcac atcgagtccc actatggcaa gccttgctaa caacctccat ctcaagatgc      900

cctcaggagg agggatggct cctcagaaca acgtggctga gagccgcatc catctgcctg      960

ccttaagccc caggagacaa atgctcacca atgggaagcc gcgattccag gtcacccagg     1020

ctggaggcat gtcagggtca catactttaa agccaaagca gcaggagttt ggaagccctt     1080

ttcctccaaa tcctgggaaa ggggctcttg gctttgggcc tcagtgcaag tccattggaa     1140

aaggcagctg caacaatcta gtggtcacca gcagtcccat gatggttcag cgactgggac     1200

tcatttcacc tccagcaagc caggtctcta cagcatgcaa ccagatcagt cctagcttac     1260

agagggcaat gaatgcagcc aacctgaata tacctccttc agataccagg tcccttattt     1320

cgcgtgagtc tttggcgtcc acgaccttga gtctgacgga aagtcagtcg gcctcaagca     1380

tgaagcagga gtggtcccag ggctacaggg ccctcccttc gctctccaac cacggctctc     1440

agaatggcct tgatctaggg gatctcctta gccttcctcc cgggacatcc atgtccagca     1500

atagtgtctc taactcatta ccatcctacc tttttggcac ggaaagtagc cactctcctt     1560

accctagtcc tcggcactca tccaccaggt cccactcggc ccgctccaag aagagagcgc     1620

tgtccttgtc cccgctgtcc gatggcatcg ggatagattt caataccatc atccgcacgt     1680

cgcccacgtc cttggtggcc tacatcaacg ggtcgagggc ttcgccggcc aacctgtccc     1740

cgcagccgga ggtctacggg catttcctgg gcgtgcgcgg cagctgcatt ccccagccgc     1800

gcccggtgcc cggcagccag aagggcgtgc tggtggcccc tggaggcctg gcgctgccgg     1860

cctacggcga ggacggggcc ctggagcacg agcgcatgca acagctggag cacggcggcc     1920

tgcagccagg cctggtcaac cacatggtgg tgcagcatgg cctgccgggc cccgacagcc     1980

agtcggccgg cctgttcaag accgaacgcc tggaggagtt cccgggcagc accgtagacc     2040

taccccccgc gcctccgctc cctcctctgc cgccgccccc aggcccccca cccccttacc     2100

atgcccatgc gcaccttcac cacccggagc tcgggcccca cgcccagcag ctggccttgc     2160

cccaggccac cctggacgac gacggggaga tggacggcat cgggggcaag cattgctgcc     2220

gctggatcga ctgcagcgcc ctgtacgacc agcaggagga gctcgtgcgg cacatcgaga     2280

aggtccacat cgaccagcgc aaaggggagg acttcacttg cttctgggcc ggttgccctc     2340

gaagatacaa gcccttcaac gcccgctata aactgctgat ccacatgaga gtccactctg     2400

gggagaagcc caacaagtgt acgtttgaag gttgcgagaa ggccttttca aggcttgaaa     2460

atctcaagat ccacttgcgg agccacacag gcgagaagcc gtatttgtgc cagcatccgg     2520

gttgtcagaa ggccttcagt aactccagtg accgcgccaa acaccagcgg acgcatctgg     2580

acaccaaacc ttatgcttgt caaattccag gatgtaccaa acgctacaca gacccaagtt     2640

ccctaagaaa gcatgtgaag gcacattctt ccaaagagca acaagcaagg aaaaagttgc     2700

ggtccagcac agagctccat ccagacctgc tcacagattg cctcaccgtg cagtccctgc     2760

agccggccac ttcccctaga gatgctgctg ctgaagggac cgtgggacgc tcccctggac     2820

ccgggcctga cctctattca gctcccattt tctccagcaa ttattcaagc cgaagtggaa     2880

cagctgctgg ggccgtacca cccccacatc ctgtcagtca cccttctcca ggacataatg     2940

tacaggggag ccctcacaac ccctcctccc agttacctcc actcacagct gtggacgcag     3000

gagctgagag gtttgcacct tctgctccat ctcctcacca catcagcccc cggagagttc     3060

cagctccttc ttcaatactg caaagaacac agcctcccta tacccagcag ccatcaggtt     3120

cacacctgaa gtcctatcag ccagaaacaa actcttcttt tcaaccaaat ggtatccatg     3180

tccatggatt ttatgggcag ctgcagaagt tctgtccccc acactacccc gattcccaga     3240

gaattgtgcc gcctgtcagc tcctgcagtg tggtgccttc gtttgaggac tgcctagtcc     3300

ctacatccat gggccaggcc agttttgatg ttttccacag agccttctcg actcactcgg     3360

gcattacagt gtatgattta ccttcaagtt cctcgagcct ctttggggag tctctccgca     3420

gcggggctga agatgctacc ttcttgcaga tcagcaccgt ggaccgctgt cctagccagc     3480

tctcctctgt ctacaccgaa ggctaaaagc tctcttggcc actcctgcac acccaggacc     3540

ttgatgttgc ttgccacctt ttgttttcgt actctcacag actgcttgag gaaggatgtc     3600

agcccaatca gcgggccctg cagagttact gatgttcttt cagaaggcag gactgaatgg     3660

cagagctagc tttgcaggaa tcattacagt tgctcctttt tctctctggt tttcctggac     3720

tatgtgacca ggaggactgt cttttcaaag ggaatttaga gcctcactct cctggatacc     3780

tgttacttcc tggctgtcaa cccttaaagg accccagtga aatgatgtgc atatgaaaat     3840

gtagtttggg gatgactcta cctgaaaact ccaaacaggg aaaaagacct caattacgag     3900

aggcatagtg acctgcctca cctaatcctc acccttgctg ctcctgatgc aaagccaggc     3960

acaacaaggg aaatccatgt ccaaagcata gtgtggtctc aactcttaga aactccctgg     4020

gtttcccttt tctcttagcc acatgctaac cagttgcttc tcagtgtttc tcttcaatag     4080

aaaaataagg ttttatatgc cagcagccta tccttgtttt tgcattttaa agacttagtt     4140

atttatacgt attttaaaat gaaaaaaaaa tgtaaaggtc tgtgctttgg atggaaatca     4200

ttattattgt aatcacccca gctatagaca ttttgcacag ctgtggttct gcctggcccc     4260

acctctagca tgttagtttt gcagttagca aaggttacct gagggaaatg gagtgggcac     4320

ctcccgcacc aacagtcctg tagctggaac cttcctgagt tgactgttta gtaactccac     4380

ctcaaagact gtgttcaaag aaaaatgttg tttgactggt ttacccattg cctccactct     4440

ggtgctgcac ccagagaagt gccagatgtg agaactggga cagactgagt catgtgccag     4500

cttcccttgg aaaaccaaac ctagtgatac ttgacttcca gtgctcagat tttactaacg     4560

tttttcagga tatccactca tctgtctgtc tcttccctac acttctctcc accctctttt     4620

tgcatccctc ttaccctctt cctgactgtg gttcatatat ccccaccagc cgccattgtc     4680

tgatcatctt gggaaggtag aggtgacagt tctcgaaaag tctacagaaa gaggcaattc     4740

tttttctgag ttccagtttg aaggcctgga attttcacat agcacttggt cgaaaatatc     4800

aagcctaaat aggaagtcat tttctgtgac acctctacat agctattaca gatcctaagt     4860

cctagggcat cagctataaa aattggccag tcccaaagac acagtaagtt ctaacattct     4920

ggtactatca tatttcaagt attttttctc actttttaaa aatgtttttc tgaacaaaag     4980

tgaaacaatg ccatttatca aactgagatc attacaatct tcaacaagac aactaaaaca     5040

gcttgatgtt agatgggatt ctgtgacagt ttgtatactg acaggtcctt ccagtctccc     5100

tccacagtcc cacaagcgga agtattctac ctgattccag agttcattcc aacatgcagt     5160

agaatgaggt gaatgaagaa ccaagtgtgg gttttgtttt cacagtgcac ttggtcaatc     5220

tagtttctct gagtagtggg ctgtattcta agaaaagctt tcacgtagac gtcaaagtct     5280

gcaaaagaga tgagttagcc actttaaaaa acctgctctg ctttacaaaa gatgcacacc     5340

aggcttcctt tacaagtgaa ctccaaggct gcttgtaaag taccaccctt cctgcagact     5400

ttgtgggtcg tgtcacttgg cctaaacaag tggcctaaca tatgcatgct cacagctagt     5460

agcatccctc atgcgtcctt tgtcatactc tggaaagaaa aaaactctgc tatcttcaga     5520

gaaaccatct attcatactt aaatatggaa gcctttacaa ggaactcaaa atacatttca     5580

tttcatttgt acaatgagaa aaaagatgaa aaggcaaggt tgttattgca gttgacattg     5640

tcagccctgc cttttggctt tatgtaattt aaaatagaaa gggggaagga ggacaagaca     5700

gaagctcaac tttagaaacc atggacatca cctccctctt tgagaggagc tgcttgtgaa     5760

ccaggctcca gtcttcctgt ggcctctcac agtaaccctg cccctttctt acctcacagg     5820

ggcaagaggg actctaaaga gggcgtaagc aatagaggca cctgcagccc tccttcctca     5880

gcaggaaatc aatgtggagc cccagaggga cattttatct cagagagagc atgctggcca     5940

caggacccag tgcagccctg cttcccgcac cgtgggtctt tcctgatagc tgcaggcttg     6000

agattgcagc ctcaggatag gacacgttca gatgccttcc agactacaca cactatgctt     6060

agattcgaga gtctttcctg accttaaaat ttgtcccttg cttactttca cactgcagaa     6120

gatttatata tatattcatc attatttttg cagcagtaca agtggaaact tcaaaaaaat     6180

cattcccttt catgtcctgg tctttttaag tcttgatatg taaccatttt cataaatgtc     6240

caaacagaga ttgtcattcc ccttaaaaac agaaacaaaa cacaaaacta gtgcttgtga     6300

aaacacacag cgcaaagaca attatcctat tgcattaaaa aaaaaatcag tctgcctaga     6360

gacatttcat tggctgcatt gtcttaattc cctaacgaaa ctgcatcaaa atgtcagttg     6420

taatttagcc tctgatcagc tgttaaatat tatttaaata tttacaggtc ctgtggggta     6480

tctcccatta cccatgtcgc cctcaaatta cataagcgat cataaaataa gaagaaaaaa     6540

aaaggtcttt agtagatcac agcagagtta ccactgataa gagtgttggc tttgttcagt     6600

tgtttctaaa ttaccagccg tcaagcacag tagcccctaa aaccaatttt gagcaaggat     6660

aaattcaact ccctcatctg agaaccttga ctttccagtt gccttgaagt attgggaata     6720

gtaactgtac attttcaatt taattatttg gtattttatt tgactgtctt ggccatgtca     6780

ttttatggaa gcatttttaa atagcacttt ttgttagtgg tgtggaattt ctgcggttat     6840

tatttttttt tttttttgca acagatgaag caaaaaaaaa aaagcactca ttggagaaat     6900

agtgagtgta aaaagagatt tattttgtac agacagcaaa gtatcctgtg taatgttgct     6960

gacataaagc actttggggg aaaaaagtgg aaatctgttt tccataaatc acacagactc     7020

ttgtacatag ttatatacac tcacgtagag aaatgaactg catatatcat actggatatg     7080

gggccgattt tactctagag gcacatctgg tgcttattgt cataaatctt ttaaagaatt     7140

aggtacactt ttttctatta atatgtatag ttttgtgatt tgtcacagtt atgtttcata     7200

taatcataag ttattttgtc ttgttcatga agtccttttt ttatgtcaaa agtaaaatga     7260

agggattgtg cacttggtac agaataaaac tggaaataga gaagacgccc tcctgcctaa     7320

aatcctcctt cagcctgtcg gtttaaaaca caatggcaac catcattgtt tgtttgtttg     7380

tttttttgtt ttgttttacc atcagcctct tacatactgg gaatggtaat tataattaaa     7440

ggcagatgat gcgggaggga atgttcaagt ccagctttaa aatgctgcat tgctttgggc     7500

cagagctgta gcctggattt aattatagat atgaggagga aatggcagta aaaatgaatg     7560

tctccctgag tcctttacat gttgggagtg tccataaata aaacatgaag ttttatttca     7620

tcagatttaa ttaaagcttt tatacatgtt aaaaaa                               7656


<210>  1489
<211>  6672
<212>  DNA
<213>  homo sapiens

<400>  1489
atcctttatg gttgaagggt gttggaggaa gcagagtttt catcagctgc tgaagtggca       60

actaatagag gtttgaatgg ccgtagaaaa atattgtgtt acttgtttgt tgtctagggg      120

ctcttggctt tgggcctcag tgcaagtcca ttggaaaagg cagctgcaac aatctagtgg      180

tcaccagcag tcccatgatg gttcagcgac tgggactcat ttcacctcca gcaagccagg      240

tctctacagc atgcaaccag atcagtccta gcttacagag ggcaatgaat gcagccaacc      300

tgaatatacc tccttcagat accaggtccc ttatttcgcg tgagtctttg gcgtccacga      360

ccttgagtct gacggaaagt cagtcggcct caagcatgaa gcaggagtgg tcccagggct      420

acagggccct cccttcgctc tccaaccacg gctctcagaa tggccttgat ctaggggatc      480

tccttagcct tcctcccggg acatccatgt ccagcaatag tgtctctaac tcattaccat      540

cctacctttt tggcacggaa agtagccact ctccttaccc tagtcctcgg cactcatcca      600

ccaggtccca ctcggcccgc tccaagaaga gagcgctgtc cttgtccccg ctgtccgatg      660

gcatcgggat agatttcaat accatcatcc gcacgtcgcc cacgtccttg gtggcctaca      720

tcaacgggtc gagggcttcg ccggccaacc tgtccccgca gccggaggtc tacgggcatt      780

tcctgggcgt gcgcggcagc tgcattcccc agccgcgccc ggtgcccggc agccagaagg      840

gcgtgctggt ggcccctgga ggcctggcgc tgccggccta cggcgaggac ggggccctgg      900

agcacgagcg catgcaacag ctggagcacg gcggcctgca gccaggcctg gtcaaccaca      960

tggtggtgca gcatggcctg ccgggccccg acagccagtc ggccggcctg ttcaagaccg     1020

aacgcctgga ggagttcccg ggcagcaccg tagacctacc ccccgcgcct ccgctccctc     1080

ctctgccgcc gcccccaggc cccccacccc cttaccatgc ccatgcgcac cttcaccacc     1140

cggagctcgg gccccacgcc cagcagctgg ccttgcccca ggccaccctg gacgacgacg     1200

gggagatgga cggcatcggg ggcaagcatt gctgccgctg gatcgactgc agcgccctgt     1260

acgaccagca ggaggagctc gtgcggcaca tcgagaaggt ccacatcgac cagcgcaaag     1320

gggaggactt cacttgcttc tgggccggtt gccctcgaag atacaagccc ttcaacgccc     1380

gctataaact gctgatccac atgagagtcc actctgggga gaagcccaac aagtgtacgt     1440

ttgaaggttg cgagaaggcc ttttcaaggc ttgaaaatct caagatccac ttgcggagcc     1500

acacaggcga gaagccgtat ttgtgccagc atccgggttg tcagaaggcc ttcagtaact     1560

ccagtgaccg cgccaaacac cagcggacgc atctggacac caaaccttat gcttgtcaaa     1620

ttccaggatg taccaaacgc tacacagacc caagttccct aagaaagcat gtgaaggcac     1680

attcttccaa agagcaacaa gcaaggaaaa agttgcggtc cagcacagag ctccatccag     1740

acctgctcac agattgcctc accgtgcagt ccctgcagcc ggccacttcc cctagagatg     1800

ctgctgctga agggaccgtg ggacgctccc ctggacccgg gcctgacctc tattcagctc     1860

ccattttctc cagcaattat tcaagccgaa gtggaacagc tgctggggcc gtaccacccc     1920

cacatcctgt cagtcaccct tctccaggac ataatgtaca ggggagccct cacaacccct     1980

cctcccagtt acctccactc acagctgtgg acgcaggagc tgagaggttt gcaccttctg     2040

ctccatctcc tcaccacatc agcccccgga gagttccagc tccttcttca atactgcaaa     2100

gaacacagcc tccctatacc cagcagccat caggttcaca cctgaagtcc tatcagccag     2160

aaacaaactc ttcttttcaa ccaaatggta tccatgtcca tggattttat gggcagctgc     2220

agaagttctg tcccccacac taccccgatt cccagagaat tgtgccgcct gtcagctcct     2280

gcagtgtggt gccttcgttt gaggactgcc tagtccctac atccatgggc caggccagtt     2340

ttgatgtttt ccacagagcc ttctcgactc actcgggcat tacagtgtat gatttacctt     2400

caagttcctc gagcctcttt ggggagtctc tccgcagcgg ggctgaagat gctaccttct     2460

tgcagatcag caccgtggac cgctgtccta gccagctctc ctctgtctac accgaaggct     2520

aaaagctctc ttggccactc ctgcacaccc aggaccttga tgttgcttgc caccttttgt     2580

tttcgtactc tcacagactg cttgaggaag gatgtcagcc caatcagcgg gccctgcaga     2640

gttactgatg ttctttcaga aggcaggact gaatggcaga gctagctttg caggaatcat     2700

tacagttgct cctttttctc tctggttttc ctggactatg tgaccaggag gactgtcttt     2760

tcaaagggaa tttagagcct cactctcctg gatacctgtt acttcctggc tgtcaaccct     2820

taaaggaccc cagtgaaatg atgtgcatat gaaaatgtag tttggggatg actctacctg     2880

aaaactccaa acagggaaaa agacctcaat tacgagaggc atagtgacct gcctcaccta     2940

atcctcaccc ttgctgctcc tgatgcaaag ccaggcacaa caagggaaat ccatgtccaa     3000

agcatagtgt ggtctcaact cttagaaact ccctgggttt cccttttctc ttagccacat     3060

gctaaccagt tgcttctcag tgtttctctt caatagaaaa ataaggtttt atatgccagc     3120

agcctatcct tgtttttgca ttttaaagac ttagttattt atacgtattt taaaatgaaa     3180

aaaaaatgta aaggtctgtg ctttggatgg aaatcattat tattgtaatc accccagcta     3240

tagacatttt gcacagctgt ggttctgcct ggccccacct ctagcatgtt agttttgcag     3300

ttagcaaagg ttacctgagg gaaatggagt gggcacctcc cgcaccaaca gtcctgtagc     3360

tggaaccttc ctgagttgac tgtttagtaa ctccacctca aagactgtgt tcaaagaaaa     3420

atgttgtttg actggtttac ccattgcctc cactctggtg ctgcacccag agaagtgcca     3480

gatgtgagaa ctgggacaga ctgagtcatg tgccagcttc ccttggaaaa ccaaacctag     3540

tgatacttga cttccagtgc tcagatttta ctaacgtttt tcaggatatc cactcatctg     3600

tctgtctctt ccctacactt ctctccaccc tctttttgca tccctcttac cctcttcctg     3660

actgtggttc atatatcccc accagccgcc attgtctgat catcttggga aggtagaggt     3720

gacagttctc gaaaagtcta cagaaagagg caattctttt tctgagttcc agtttgaagg     3780

cctggaattt tcacatagca cttggtcgaa aatatcaagc ctaaatagga agtcattttc     3840

tgtgacacct ctacatagct attacagatc ctaagtccta gggcatcagc tataaaaatt     3900

ggccagtccc aaagacacag taagttctaa cattctggta ctatcatatt tcaagtattt     3960

tttctcactt tttaaaaatg tttttctgaa caaaagtgaa acaatgccat ttatcaaact     4020

gagatcatta caatcttcaa caagacaact aaaacagctt gatgttagat gggattctgt     4080

gacagtttgt atactgacag gtccttccag tctccctcca cagtcccaca agcggaagta     4140

ttctacctga ttccagagtt cattccaaca tgcagtagaa tgaggtgaat gaagaaccaa     4200

gtgtgggttt tgttttcaca gtgcacttgg tcaatctagt ttctctgagt agtgggctgt     4260

attctaagaa aagctttcac gtagacgtca aagtctgcaa aagagatgag ttagccactt     4320

taaaaaacct gctctgcttt acaaaagatg cacaccaggc ttcctttaca agtgaactcc     4380

aaggctgctt gtaaagtacc acccttcctg cagactttgt gggtcgtgtc acttggccta     4440

aacaagtggc ctaacatatg catgctcaca gctagtagca tccctcatgc gtcctttgtc     4500

atactctgga aagaaaaaaa ctctgctatc ttcagagaaa ccatctattc atacttaaat     4560

atggaagcct ttacaaggaa ctcaaaatac atttcatttc atttgtacaa tgagaaaaaa     4620

gatgaaaagg caaggttgtt attgcagttg acattgtcag ccctgccttt tggctttatg     4680

taatttaaaa tagaaagggg gaaggaggac aagacagaag ctcaacttta gaaaccatgg     4740

acatcacctc cctctttgag aggagctgct tgtgaaccag gctccagtct tcctgtggcc     4800

tctcacagta accctgcccc tttcttacct cacaggggca agagggactc taaagagggc     4860

gtaagcaata gaggcacctg cagccctcct tcctcagcag gaaatcaatg tggagcccca     4920

gagggacatt ttatctcaga gagagcatgc tggccacagg acccagtgca gccctgcttc     4980

ccgcaccgtg ggtctttcct gatagctgca ggcttgagat tgcagcctca ggataggaca     5040

cgttcagatg ccttccagac tacacacact atgcttagat tcgagagtct ttcctgacct     5100

taaaatttgt cccttgctta ctttcacact gcagaagatt tatatatata ttcatcatta     5160

tttttgcagc agtacaagtg gaaacttcaa aaaaatcatt ccctttcatg tcctggtctt     5220

tttaagtctt gatatgtaac cattttcata aatgtccaaa cagagattgt cattcccctt     5280

aaaaacagaa acaaaacaca aaactagtgc ttgtgaaaac acacagcgca aagacaatta     5340

tcctattgca ttaaaaaaaa aatcagtctg cctagagaca tttcattggc tgcattgtct     5400

taattcccta acgaaactgc atcaaaatgt cagttgtaat ttagcctctg atcagctgtt     5460

aaatattatt taaatattta caggtcctgt ggggtatctc ccattaccca tgtcgccctc     5520

aaattacata agcgatcata aaataagaag aaaaaaaaag gtctttagta gatcacagca     5580

gagttaccac tgataagagt gttggctttg ttcagttgtt tctaaattac cagccgtcaa     5640

gcacagtagc ccctaaaacc aattttgagc aaggataaat tcaactccct catctgagaa     5700

ccttgacttt ccagttgcct tgaagtattg ggaatagtaa ctgtacattt tcaatttaat     5760

tatttggtat tttatttgac tgtcttggcc atgtcatttt atggaagcat ttttaaatag     5820

cactttttgt tagtggtgtg gaatttctgc ggttattatt tttttttttt tttgcaacag     5880

atgaagcaaa aaaaaaaaag cactcattgg agaaatagtg agtgtaaaaa gagatttatt     5940

ttgtacagac agcaaagtat cctgtgtaat gttgctgaca taaagcactt tgggggaaaa     6000

aagtggaaat ctgttttcca taaatcacac agactcttgt acatagttat atacactcac     6060

gtagagaaat gaactgcata tatcatactg gatatggggc cgattttact ctagaggcac     6120

atctggtgct tattgtcata aatcttttaa agaattaggt acactttttt ctattaatat     6180

gtatagtttt gtgatttgtc acagttatgt ttcatataat cataagttat tttgtcttgt     6240

tcatgaagtc ctttttttat gtcaaaagta aaatgaaggg attgtgcact tggtacagaa     6300

taaaactgga aatagagaag acgccctcct gcctaaaatc ctccttcagc ctgtcggttt     6360

aaaacacaat ggcaaccatc attgtttgtt tgtttgtttt tttgttttgt tttaccatca     6420

gcctcttaca tactgggaat ggtaattata attaaaggca gatgatgcgg gagggaatgt     6480

tcaagtccag ctttaaaatg ctgcattgct ttgggccaga gctgtagcct ggatttaatt     6540

atagatatga ggaggaaatg gcagtaaaaa tgaatgtctc cctgagtcct ttacatgttg     6600

ggagtgtcca taaataaaac atgaagtttt atttcatcag atttaattaa agcttttata     6660

catgttaaaa aa                                                         6672


<210>  1490
<211>  4850
<212>  DNA
<213>  homo sapiens

<400>  1490
agtgcggagc cttaggcgga gcgaagagaa ccggtcgcgg caatcctagc gcgcagcagc       60

agcagcagca gcagcagcag cagcagcagc agcagcagca cccgcatccg ctgcgggagt      120

ccgagccgga accacaccca agtagctgcc ctttcctctt ctgtcatctc accgccccac      180

cacagaccgc gttccccgag gaaaccggcc gcccacgccc ggagcatcct cccctgttga      240

gcgggcgctg acggacccgg cggcatgatg cggctgcgag gctcggggat gctgcgggac      300

ctgctcctgc ggtcgcccgc cggcgtgagc gcgactctgc ggcgggcaca gcccttggtc      360

accctgtgcc ggcgtccccg aggcggggga cggccggccg cgggcccggc tgccgccgcg      420

cgactccacc cgtggtgggg cgggggcggc tggccggcgg agcccctcgc gcggggcctg      480

tccagctctc cttcggagat cttgcaggag ctgggcaagg ggagcacgca tccgcagccc      540

ggggtgtcgc cacccgctgc cccggcggcg cccggcccca aggacggccc cggggagacg      600

gacgcgtttg gcaacagcga gggcaaagag ctggtggcct caggtgaaaa taaaataaaa      660

cagggtctgt tacctagctt ggaagatttg ctgttctata caattgctga aggacaagag      720

aaaatacctg ttcataaatt tattacagca ctcaaatcta caggattgcg aacgtctgat      780

cccaggttga aagagtgtat ggatatgtta agattaactc ttcaaacaac atcagatggt      840

gtcatgctag acaaagatct ttttaaaaaa tgtgttcaga gcaacattgt tttgttgaca      900

caagcattta gaagaaagtt tgtgattcct gactttatgt cttttacctc acacattgat      960

gagttatatg aaagtgctaa aaagcagtct ggaggaaagg ttgcagatta tattcctcaa     1020

ctggccaaat tcagtcccga tttgtggggt gtgtctgttt gtacagtaga tggacagagg     1080

cattctactg gagataccaa agttcccttc tgtcttcagt cctgtgtaaa acctttgaaa     1140

tatgccattg ctgttaatga tcttggaact gaatatgtgc atcgatatgt tggaaaagag     1200

ccgagtggac taagattcaa caaactattt ttgaatgaag atgataaacc acataatcct     1260

atggtaaatg ctggagcaat tgttgtgact tcactaataa agcaaggagt aaataatgct     1320

gaaaaatttg actatgtcat gcagtttttg aataagatgg ctggtaatga atatgttgga     1380

ttcagtaatg caacgtttca gtctgaaaga gaaagtggag atcgaaattt tgcaatagga     1440

tattacttaa aagaaaagaa gtgttttcca gaaggcacag acatggttgg tatattagac     1500

ttctacttcc agctgtgctc cattgaagtg acttgtgaat cagccagtgt gatggctgcg     1560

acactggcta atggtggttt ctgcccaatt actggtgaaa gagtactgag ccctgaagca     1620

gttcgaaata cattgagttt gatgcattcc tgtggcatgt atgacttctc agggcagttt     1680

gctttccatg ttggtcttcc tgcaaaatct ggagttgctg ggggcattct tttagttgtc     1740

cccaatgtta tgggtatgat gtgctggtct cctcctctgg ataagatggg caacagtgtt     1800

aagggaattc acttttgtca cgatcttgtt tctctgtgta atttccataa ctatgataat     1860

ttgagacact ttgcaaaaaa acttgatcct cgaagagaag gtggtgatca aagggtaaag     1920

tcagtgataa atcttttgtt tgctgcatat actggagatg tgtctgcact tcgaagattt     1980

gctttgtcag ctatggacat ggaacagcgg gactatgatt ctagaacagc actccatgta     2040

gctgctgcag agggtcatgt tgaagttgtt aaatttttgc tggaagcctg caaagtaaac     2100

cctttcccca aggacaggtg gaataacact cccatggatg aagcactgca ctttggacac     2160

catgatgtat ttaaaattct ccaagaatac caagtccagt acacacctca aggagattct     2220

gacaacggga aggaaaatca aaccgtccat aagaatcttg atggattgtt gtaatggtct     2280

caaatcccaa gatttaaatc acttacctat ttaattgtgg aaaatgatta tgaagaacat     2340

gtgtatttct atctggtagt gatgtatatt ttacatttgt catttcagtg ttactggagt     2400

tttcttcatt gtgcacacag gacaaatctg atctctttgg gaaaaaatag aaataaaaca     2460

atctccctcc ataatgtgag caatattacc tcgtgcattg tataatttga tgtaaaagaa     2520

atagttacca atgctagctt gtgtggtctt ccatgattta tttgtgtttt gtgaattttc     2580

aatttatggt gatgatctgc tgatatgcat ttataaagta agctctgttg tacagtctgt     2640

ccaaatgggt caaggttgcc tttagaagca aatagtgtga ttttcaagac ttcaaataca     2700

aatttagttt aagtgtttga acaactatat gcacttacgg ttgtgtgttt aaaatgtctc     2760

tctcaccccc tagcttcatg atgtgactct taaaaaacta taatagttaa caactgttag     2820

taagatagac caattctgat tagactttat cagggaatct gtttaagata tgtttggtga     2880

ccaaaacgta tgtgtgaatg tagttataat gcttttgaaa aattttcctt tttctatatc     2940

cccttagtcc agcctctctt ctcagacatt tagctatctg cctctttcct ttagctggga     3000

aagtgagagc tggcatacta tgcagttttt atgttttcca tagtaagtca gaaaatgcct     3060

cctatttctg gcatcagaac tttgccattt gtctacagaa gacgaaccag agacaaaatt     3120

actaagtata aattagtcaa gtttatcagt ctaaaaaacg aagggatgtg caactgcagc     3180

tctttaagaa gttttttttt tttagcttct agggtaaaga taaattcaga aatgctctaa     3240

gctaccaaag ttattctgaa agtatgggaa ctgctacaac taacaaacat ttgtttccaa     3300

gcctgtcatt aagagtctgc atcaagagat ttgtcctcct tgggggacca ctggatcatt     3360

ccagatttct tgtgattttt ctattgtgta attcttggtg ggctctgtag tttaataata     3420

agaaaaaggc catttcattt taaattgtga cctataattc tttgtcttgg gttggtaatt     3480

caggattcat ttggaaagtg ggtaaaaggg gcttcaaaaa acggatagaa caggattttc     3540

taggagttac acatacattt tatcctgtca tacctcgaga taaagtggca tgttagtgag     3600

gagttctgat attaagcaca cacacacatg cacacaaatg gacttctctg aagctgtgtt     3660

tagtgaaatg agctcaagta catgaatgtt agttgttatc acatacagca aattcctttt     3720

tttttctttt tctatgagca cactctgctg cttctaaact ttacatgcct gatggcacct     3780

tactccagca gcctccaggt gctttcattt tcacttccag tctaagccag tggctcctgc     3840

cactgccctc ccattaccta gatggcacct cctttggtga aaccacggcc aatgttcctt     3900

agctgcacca ggcccgaagc tgttcccatg cttgagcttc catggggagg atgctgagtg     3960

agcagtttcc taccccgtgg atctagcaag ccatggagac aggtagcatt tgtaagatgc     4020

tgcacaggag cagcattatc cccaaagata ttacagggta gacacgtttt aactgaaatc     4080

aatcaagata actttattca aagagcagcc cgctttgtgt gactaaaatg aaacaagaca     4140

gttgaattgt gtgacttgaa gattaccaat gattttgagg cttttctata ataaaaagag     4200

gttctaacca ttatttggga acaaagagag ttttcatctt ttttcagatc aaaaccattc     4260

tgtaaaatct ttgttgttta attaaatgtg ccgttattta cccctgatgt tatttatgac     4320

tatgtgccga ttcctgctcg ggctgtttgc tgttggctgg taataatata tttgatttaa     4380

atgctgttga ctgtgctatt aactgctgcc gtcagtaaac tccaaagatc tttttgtttt     4440

ggctttagta tcatatgtgc tttttctgta tcctgagcgc tctatatgat catgttaatt     4500

taaagcttta tacacattgt tgtttttgct ggtctcatct ttggtaatat gctatacccc     4560

actgctgccc gacactgccc tttagctgca gagctggatt agctgttgac catttgatgc     4620

tgttgtctgt ctggcaggga ctgaatgacc tgatgtcaga tttagattct tcctggggat     4680

tacacagcta tgaatgtatt tgcttctaaa acctcccaaa gtgaatctaa tcttaaaact     4740

acaagttgta agtattctga aattgggaaa catttatttt aaatgcaatc aggtagtgtt     4800

gctttttaca gcataataaa tatatgtatc aaaaaaaaaa aaaaaaaaaa                4850


<210>  1491
<211>  4838
<212>  DNA
<213>  homo sapiens

<400>  1491
accagtacca gcccccacct tccgtctgtg catgttttct tcagtcctgg aaggaaatca       60

taagtgattt gccccaaaag gattgctgtt gaaaatggag caagagccac aaaatggaga      120

acctgctgaa attaagatca tcagagaagc atataagaag gcctttttat ttgttaacaa      180

aggtctgaat acagatgaat taggtcagaa ggaagaagca aagaactact ataagcaagg      240

aataggacac ctgctcagag ggatcagcat ttcatcaaaa gagtctgaac acacaggtcc      300

tgggtgggaa tctgctagac agatgcaaca gaaaatgaaa gaaactctac agaatgtacg      360

caccaggctg gaaattctag agaagggtct tgccacttct ctgcagaatg atcttcagga      420

ggtgcccaag ttatatccag aatttccacc taaagacatg tgtgaaaaat taccagagcc      480

tcagtctttt agttcagctc ctcagcatgc tgaagtaaat ggaaacacct caactccaag      540

tgcaggggca gttgctgcac ctgcttctct gtctttacca tcacaaagtt gtccagcaga      600

agctcctcct gcttatactc ctcaagctgc tgaaggtcac tacactgtat cctatggaac      660

agattctggg gagttttcat cagttggaga ggagttttat aggaatcatt ctcagccacc      720

gcctcttgag accttagggc tggatgcaga tgaattgatt ttgataccaa atggagtaca      780

gatttttttt gtaaatcctg caggggaggt tagtgcacct tcgtatcctg ggtaccttcg      840

aattgtgagg tttttggata attctctcga tacggttcta aaccgtcctc ccgggtttct      900

tcaggtttgt gactggttat atcctctagt tcctgataga tctccggttc tgaaatgtac      960

tgcgggagcc tacatgtttc ctgatacaat gctacaagca gcaggatgct ttgtgggggt     1020

cgtcctgtcc tctgagttac cagaggatga tagagagctc tttgaggatc tgttaaggca     1080

aatgtctgac cttcggctcc aggccaactg gaacagagca gaagaagaaa atgaattcca     1140

aatccctgga agaactagac cctcctctga ccaactaaaa gaagcctctg gcactgatgt     1200

gaaacagttg gaccaaggca ataaggatgt acgtcataaa ggaaaacgtg gaaaaagggc     1260

taaagatact tcaagtgaag aagttaacct gagtcacatt gtaccatgtg agccagttcc     1320

agaagaaaag ccaaaagaat tacctgaatg gagtgaaaaa gtggctcaca acattttgtc     1380

aggtgcttcc tgggtgagtt ggggtttagt caaaggtgct gagattactg gtaaggcaat     1440

ccagaaaggt gcttctaaac tccgagagcg gattcaacca gaagaaaaac ccgtggaagt     1500

tagtccagct gtcaccaagg gactttatat agcgaagcaa gctacaggag gagcagcaaa     1560

agtcagtcag ttcctggttg atggagtttg cactgtagca aattgcgttg gaaaagaact     1620

agctccacat gtcaagaagc atggaagcaa acttgttcca gaatctctta aaaaagacaa     1680

agatgggaaa tctcctctgg atggtgctat ggttgtagca gcaagtagtg ttcaaggatt     1740

ttcaactgtc tggcaaggat tggaatgtgc agctaaatgc atcgttaaca atgtttcagc     1800

agaaactgta caaactgtca gatacaaata cggatataat gcaggagaag ctacccacca     1860

tgcggtggat tctgcggtca atgttggcgt aactgcctac aatattaaca acattggtat     1920

caaagcaatg gtgaagaaaa ctgcaacaca aacaggacac actctccttg aggactatca     1980

gatagttgat aattctcaga gggaaaatca agaaggagca gcaaatgtca acgtgagagg     2040

ggagaaggat gagcagacga aggaagtaaa ggaggcaaag aagaaagata aatgatgaag     2100

tgctgggaat cacttatacc aaagccttat gaaatggatg aaattttgtt aaataggcaa     2160

atgtggaatt cctcacagat taaccagtat tttttaaatg tattcattcc tacaaattaa     2220

ctttcataaa ttttatggca tgtcttctat ttaaaaggaa aagaataagt attcttgcat     2280

ctggccttag aaatgtgaag ttatattctc aagtttattt ttttccaagt gtagctaaaa     2340

tatttttgca ggtaaaataa agctgatagt acatgtgttg ttcaaacctt gttaaaccta     2400

atattgaact atttttatat ctgctgtctt tcagaaggca aataggaaac tatatatttg     2460

cttaaaaatt ggcatttagt aaccttaatt ctttttatag aaggaatgac ttaaagtatt     2520

gtcccctctt tttgcactaa ttgtggattt ttttagatgc ttctcaaaat tttcagtgtg     2580

taagctaaac aaaaactaaa actaagaatt ctcaaaaaaa cttgttcaaa acagggaaag     2640

actgatgaaa agtaaaatgg actacttttg taacttacct gtttgttagg aaatggaatg     2700

gtctctttga tttaaaataa ataaaaatag attattacgt cttttgtatt gagactgtat     2760

tgttatgagc ctaggaaatt tgggaacatg attgtattgt attaaaattc gaagtgatta     2820

ttatcagctt aattggatta aaaaagtact tcaagaaatt attttatcat atctgcttct     2880

gtttttccaa aaggttaaaa cttgtaaaaa aaatatatat aaacaattga gtttactaat     2940

ggtaaacatt tttattctgg gattcggtca ttggaattta tattaaaaga caagttatta     3000

aaaaggaaag gttctattca taatcagggt aaagaatatg aaaaccttag acgtaatcca     3060

tggtggatag gcattatggt ttccactttg gcagaaggca gactattcac agccctattt     3120

acttacatag gctaaaaaac tatgtaacta aatacctaat ggtatttaat ttttgtttat     3180

tgaatttaag agattggtat tagttttcat agctgtagtc cattctaata atttctgatc     3240

ttctagtggc tacttaatta gacattattt gaagctgtct gaagaatgca ctttatgaat     3300

taaaaaactg aattgcctga cctcgttatc acatgagctt atattttggg aacacataga     3360

actgatggag gcttttccta aggccaagga taatgtacta gttgttaaaa tggaaataaa     3420

agtgaagtgg taaatagctt acagacagtc tatgctttgt ttaagaaatg gaatggcact     3480

tcatatattc tcatttgtgg gagctaaaaa ttacaataat caaacttaag gagatagaga     3540

gtagaatgat ggttaccaga ggctgggagg cattgaaggg atggggaggg aagtgaggtt     3600

gattaatggg tacgaaaata tagttagaac gaatttgttg tagtatttga tagcccaaca     3660

gggtgactac agtcaacaat aactttatac atttaaaaat aaaagagtgt aattgggacg     3720

tttgtaacac aaatgaatgc ttgaagcagt agatacaccc tgatgtaatt attataaatc     3780

gcatacctgt atcaaaatat ctcatgtatc ccataaatat atacacctac catgtaccca     3840

taaaaattta aaaagaaatg gaatggcaaa taatggaaca taaactttaa acagttagct     3900

ttgaccagag gtcagcaaat atcctccatg ggctaaatcc agatgtccac ctgttttcat     3960

aaataacgtt ttattggagc atagctgtac ccatttgttt acatattggc tatggctgct     4020

gtctagttca acgtgagagt tgaatagttg catcagagag tatatggtcc acaagcctaa     4080

cttattcact ctctggccct ttgcagaaaa agtgtgctgc cttagtctat agaaaatgga     4140

cttttcccac cattcactga ctcattagga gataggcatc ttctaaagat tttttttata     4200

ttgtgtaatg attgatatat agataaaatt atatattact tgtaaggtat gatgaataac     4260

aacacttaaa aactcatcac acctaaagac atggaaagct gccaattacc tatatgtatg     4320

ttcttcctat tttcttacct ctttccccat gtcatttttt attgttcctt gccatttttt     4380

aatcacacat gtatgttctc caaacatact gtttcatttt ttgaagcttt ctacatatag     4440

tgtctgaatg tgaagtctta ctcaacttgc ttttttgagt ttatgtttaa aattcattct     4500

tgcgcttata tgcatggatg gtttacttgc tctatagtat tctgtgtgag tataccacaa     4560

tttaagtgtt cattttccta tcagttgaca tttgttttta gtttttgttg gtagaaacag     4620

tacactcaaa acatccttga ctgtcccctg gtacacatat gcaagagact ttatgcgtaa     4680

gagtggagtt gttggcttgt caagttttgc aaaataatgc caggtatttt ccaaaatgat     4740

gatattctct tgagtattac ttccctttgc aatgttttta ttgttaatgt agcatatata     4800

aaaaagtatc tcataatttt aaaaaaaaaa aaaaaaaa                             4838


<210>  1492
<211>  2119
<212>  DNA
<213>  homo sapiens

<400>  1492
gggtctgcgg gaagcccgag ccggggcggg cccgagtcaa aggcaagtga aggtggaagc       60

ggccgcggcg gcagcagacc ccagagtcag aaggagtgag aaccctgacc cctaatccca      120

ctgcatccag ccaataggag cccagccacc atggcggagc tgcaggaggt gcagatcaca      180

gaggagaagc cactgttgcc aggacagacg cctgaggcgg ccaaggaggc tgagttagct      240

gcccgaatcc tcctggacca gggacagact cactctgtgg agacaccata cggctctgtc      300

actttcactg tctatggcac ccccaaaccc aaacgcccag cgatccttac ctaccacgat      360

gtgggactca actataaatc ttgcttccag ccactgtttc agttcgagga catgcaggaa      420

atcattcaga actttgtgcg ggttcatgtg gatgcccctg gaatggaaga gggagcccct      480

gtgttccctt tgggatatca gtacccatct ctggaccagc ttgcagacat gatcccttgc      540

gtcctgcagt acctaaattt ctctacaata attggagttg gtgttggagc tggagcctac      600

atcctggcga gatatgctct taaccacccg gacactgttg aaggtcttgt cctcatcaac      660

attgatccca atgccaaggg ttggatggat tgggcagccc acaagctaac aggcctcacc      720

tcttccattc cggagatgat ccttggacat cttttcagcc aggaagagct ctctggaaat      780

tctgagttga tacaaaagta cagaaatatc attacacatg cacccaacct ggataacatt      840

gaattgtact ggaacagcta caacaaccgc cgagacctga actttgagcg tggaggtgat      900

atcaccctca ggtgtcctgt gatgctggtg gtaggagacc aagcacctca tgaagatgca      960

gtggtggaat gtaactcaaa actggacccc acccagacct cgttcctcaa gatggctgac     1020

tccggaggtc agccccagct gactcagcca ggcaagctga ccgaggcctt caagtacttc     1080

ctgcaaggca tgggctacat ggcctcatcc tgcatgactc gcctgtcccg gtctcgtaca     1140

gcctctctga ccagtgcagc atccgttgat ggcaaccggt cccgctctcg caccctgtcc     1200

cagagcagcg agtctggaac tctttcttcg gggcccccgg ggcacaccat ggaggtctcc     1260

tgttgaatgg cccttgttgc cctagagtgg gacccagccc tcacctcccc cagagctaac     1320

ctgggaggtg ctgaaggggc attgggccac cgtaagcaag ggaaaaaggg cagatcatgc     1380

ggggagatga ccttgatctt tgattgctac cctaaccttg acctttaacc cgtgattccc     1440

cccagctcct ggaagagatg tcctaatatc tcttagggac ccagacccct aaattctcct     1500

cctcccccat tttgatgtta aggtggagag ggcatatgca tcctctgtcc tgatctaggt     1560

gtctatagct gaggggtaag aggttgttgt agttgtcctg gtgcctccat cagactctcc     1620

ctacttgtcc catatttgca aggggagggg atttggggct ggggctccat tcaccaaagc     1680

tgaggtggct tctcattaac cctttaggac tctgaagggt atggacctac gtgaatgtgt     1740

gtcaggggga gacttgctgg tgggttagtg gtcctcagga tgtgatagaa acatccagtg     1800

taaaaaggaa gttggaatgg gagttggcgg gcagtgaacg agtgtgggga aggattggtg     1860

ctggggcaac aggaaggggc ctggggccgt ttggctgcac taactttggt agctcagtgt     1920

gcatctagag tgggactggg gagggagcta agcttgggct gggctgcttg gggcttggca     1980

tagggtggaa agggctaccc tggggctctg accacactgt agtatgtgtg gagggtgccc     2040

tcccgtctcc cacaacttct gctataacaa taaactgtag aggaatctga gtaccgttaa     2100

aaaaaaaaaa aaaaaaaaa                                                  2119


<210>  1493
<211>  2077
<212>  DNA
<213>  homo sapiens

<400>  1493
gggtctgcgg gaagcccgag ccggggcggg cccgagtcaa aggcaagtga aggtggaagc       60

ggccgcggcg gcagcagacc ccagagtcag aaggagtgag aaccctgacc cctaatccca      120

ctgcatccag ccaataggag cccagccacc atggcggagc tgcaggaggt gcagatcaca      180

gaggagaagc cactgttgcc aggacagacg cctgaggcgg ccaagactca ctctgtggag      240

acaccatacg gctctgtcac tttcactgtc tatggcaccc ccaaacccaa acgcccagcg      300

atccttacct accacgatgt gggactcaac tataaatctt gcttccagcc actgtttcag      360

ttcgaggaca tgcaggaaat cattcagaac tttgtgcggg ttcatgtgga tgcccctgga      420

atggaagagg gagcccctgt gttccctttg ggatatcagt acccatctct ggaccagctt      480

gcagacatga tcccttgcgt cctgcagtac ctaaatttct ctacaataat tggagttggt      540

gttggagctg gagcctacat cctggcgaga tatgctctta accacccgga cactgttgaa      600

ggtcttgtcc tcatcaacat tgatcccaat gccaagggtt ggatggattg ggcagcccac      660

aagctaacag gcctcacctc ttccattccg gagatgatcc ttggacatct tttcagccag      720

gaagagctct ctggaaattc tgagttgata caaaagtaca gaaatatcat tacacatgca      780

cccaacctgg ataacattga attgtactgg aacagctaca acaaccgccg agacctgaac      840

tttgagcgtg gaggtgatat caccctcagg tgtcctgtga tgctggtggt aggagaccaa      900

gcacctcatg aagatgcagt ggtggaatgt aactcaaaac tggaccccac ccagacctcg      960

ttcctcaaga tggctgactc cggaggtcag ccccagctga ctcagccagg caagctgacc     1020

gaggccttca agtacttcct gcaaggcatg ggctacatgg cctcatcctg catgactcgc     1080

ctgtcccggt ctcgtacagc ctctctgacc agtgcagcat ccgttgatgg caaccggtcc     1140

cgctctcgca ccctgtccca gagcagcgag tctggaactc tttcttcggg gcccccgggg     1200

cacaccatgg aggtctcctg ttgaatggcc cttgttgccc tagagtggga cccagccctc     1260

acctccccca gagctaacct gggaggtgct gaaggggcat tgggccaccg taagcaaggg     1320

aaaaagggca gatcatgcgg ggagatgacc ttgatctttg attgctaccc taaccttgac     1380

ctttaacccg tgattccccc cagctcctgg aagagatgtc ctaatatctc ttagggaccc     1440

agacccctaa attctcctcc tcccccattt tgatgttaag gtggagaggg catatgcatc     1500

ctctgtcctg atctaggtgt ctatagctga ggggtaagag gttgttgtag ttgtcctggt     1560

gcctccatca gactctccct acttgtccca tatttgcaag gggaggggat ttggggctgg     1620

ggctccattc accaaagctg aggtggcttc tcattaaccc tttaggactc tgaagggtat     1680

ggacctacgt gaatgtgtgt cagggggaga cttgctggtg ggttagtggt cctcaggatg     1740

tgatagaaac atccagtgta aaaaggaagt tggaatggga gttggcgggc agtgaacgag     1800

tgtggggaag gattggtgct ggggcaacag gaaggggcct ggggccgttt ggctgcacta     1860

actttggtag ctcagtgtgc atctagagtg ggactgggga gggagctaag cttgggctgg     1920

gctgcttggg gcttggcata gggtggaaag ggctaccctg gggctctgac cacactgtag     1980

tatgtgtgga gggtgccctc ccgtctccca caacttctgc tataacaata aactgtagag     2040

gaatctgagt accgttaaaa aaaaaaaaaa aaaaaaa                              2077


<210>  1494
<211>  3779
<212>  DNA
<213>  homo sapiens

<400>  1494
ctctttaagg tgcccgaggc tcgcgggcgc tgcgctgagg ggacggcggg aggcgcggcc       60

tggcctcgca ctcaaagccg ccgcagcgcg ccccgggctc ggccgacccg gcggggatct      120

aggggtgggc gacttcgcgg gaccgtggcg catgtttcct gggagttact gatcatcttc      180

tttgaagaaa catgaagtta cactatgttg ctgtgcttac tctagccatc ctgatgttcc      240

tgacatggct tccagaatca ctgagctgta acaaagcact ctgtgctagt gatgtgagca      300

aatgcctcat tcaggagctc tgccagtgcc ggccgggaga aggcaattgc tcctgctgta      360

aggagtgcat gctgtgtctt ggggcccttt gggacgagtg ctgtgactgt gttggtatgt      420

gtaatcctcg aaattatagt gacacacctc caacttcaaa gagcacagtg gaggagctgc      480

atgaaccgat cccttctctc ttccgggcac tcacagaagg agatactcag ttgaattgga      540

acatcgtttc tttccctgtt gcagaagaac tttcacatca tgagaatctg gtttcatttt      600

tagaaactgt gaaccagcca caccaccaga atgtgtctgt ccccagcaat aatgttcacg      660

cgccttattc cagtgacaaa gaacacatgt gtactgtggt ttattttgat gactgcatgt      720

ccatacatca gtgtaaaata tcctgtgagt ccatgggagc atccaaatat cgctggtttc      780

ataatgcctg ctgcgagtgc attggtccag aatgtattga ctatggtagt aaaactgtca      840

aatgtatgaa ctgcatgttt taaagaagac aaatgcaaac caaagcaact tagtaaaata      900

ataggtataa aaagttattc tgtaagtctg ttggttgtat cttgtatcag aatcccagta      960

agttaagttg taaagacttt ggaataagtt tcttttaaaa atatgacata gccagtgatg     1020

tgtttaatta tataactgtt cttactgatt ttattgcccc ctagcaataa gccctttcct     1080

ttgaatacat gtacaacttt ggtcatatga gaagcaggtg cgcagagaat tccttgaaag     1140

atctgaggtt tttaacatga agtctgatgt ggttttcctc tagcattcca aaaggttttt     1200

gctttgaaag tgttagcaga agcatgttga tgtgaattat gatttcttca tgtgctactg     1260

ttagcacact gagtttttat agttgcacat cattcctcat tgtgccttgt tttatccatt     1320

ttataaatag agtagatatt tgatatacca ctctgataac tcatataaaa atatcatcat     1380

aaaaagctta atttcatccc ttttatgttg gttttaaaag gtaaatgctt accatatttt     1440

ataattgaga actcttacat agtagaatcc attctataat acatgtgttg acaaagcttt     1500

agagaaagtt tcctattctc ttccatttcc cctgcccaaa gtgctgacat aggcagtgat     1560

gaagaatctt taccaagatt ttcagggtgt acctatgaaa ttgctttaaa tgcactgctg     1620

gtgtaaataa ttagcaagca aaagcgtttc tgtgacttca ggtaccagct taaagagcac     1680

tagggatggg gaacgaatgc caaatcagac tccacctaga gcaccaggaa acagcttgta     1740

ccctggtagg gaaatggtgt tgctgaaagg ggaggctgag ccagtgcgag actgaacttg     1800

tgcagcctta gccaagacaa agcagtgttt ttcagcagac ggctgatggg acaggaattg     1860

aagaagagaa ttgactcgta tgaacaggac agggtgaaaa tgctgggaat tataatggga     1920

aacaaaacta tctatgttca tattttgtaa tatttcattt gttaagttta tatctggata     1980

taatgttctt tttaaacaag tataatcata tcgtcggagg ttaagattat gaaattttag     2040

aatctctatt caagatgatg ttcactccaa atacactaca gaatttagtc aacattttat     2100

ataatgtttc aataaatgtt tctttcaata aagatactat gtgcccttca tagtaataaa     2160

atctcaatct taaagcatga atctaaaaca taaatattta tattacagac tcaattttac     2220

aaaattacta attgctctag tgcatatttg aactacaagc aactttttag gaatacctct     2280

ttatacgtct acatatttta gtatataaaa atagataatg ctcttggaca cattttgtat     2340

tattcatgat ctgaatagta gttagttaaa agatcatttg taatattatg atcaactgtt     2400

ataaattaag gtcttaatac cttttctgct ctttcaaata actctaatga atattcaaga     2460

tattttagcc ttttaaaaag ttgagattta gctcatggat atattttttg gtagggaaac     2520

attagggtct ccttttcttc cttttaccta gaatgcctca tttaaaagtg ccttgaaaac     2580

atttagctcc ccttcttcat gagcatctgt agagctgaaa gtattctgga actttagaca     2640

gaaagctgaa aggaatctgc agtctcctgc tgcagttcaa ctctgctgtt tttcagtcat     2700

ttcctactgt gagtggagtg atgtttgtgt gtgtgttggc aacatgccta atgttttctt     2760

aatgatgaca acaaatattt taaaactgca tttatcattt tttaggtctt cattaaattt     2820

taaaatgtaa tatctgtttc ccacccccta cattaggagg ataatttctt aaaccacatt     2880

gttttaattg atttttctta tcttgatttc tttcattaga aactatccct aaatgtaaag     2940

atcttttgcc ttcaaatttg gcttattttt tctgatttat gagggtttga aagaaagaat     3000

tcacctaaaa gattccattt ccagttttat aatgtatttc aggttctgaa taacaatatt     3060

tttccaaatt gaaagtaaat attcaagaag ttgatagcct ggttaaaagt tagatcctct     3120

attaccattc taagcacatt cacttctata ttgaagtttt ggtaaaaatt cttttttctt     3180

ttttaataaa aaattaggtt attacttttt ttataaccag atttttaaag cactaggttt     3240

taaatcagtg ggtatcataa aagccatata taaaagatcc tttcttatag taagacttgt     3300

gcttgttagc aggtttttct gttagttttt cccccataac atttaattat tactaaaatt     3360

gtatttacaa tagtggtgcc aaatcaaatg gtaatttaaa taaaatctat tctgtgttta     3420

tgtagggtgg tataaaaaag aggtcttcat ttagacatgt gatttctaaa attccagaaa     3480

gcaaaattga taagatgtta gaaatttgga ccgttattta taatcagggt agcattaaaa     3540

tggagaaaag aaagttttct gaaaaaatgc agtaaatata agccacattt ctaaagttta     3600

tttttatgaa agcttctttt aagattttga aatctattct gcattcccaa gagtttatgt     3660

ttattgtatt ttatatgatc tacaacatat aaaattgtgt atttttcttt ggttgtccct     3720

attaacaaaa aagtatttta ataaaaaatt gaaatgaaaa aaaaaaaaaa aaaaaaaaa      3779


<210>  1495
<211>  3276
<212>  DNA
<213>  homo sapiens

<400>  1495
acgtagaccc ggatccccag ctcccggacc ccttccgact gctcccttcg ccactcgcgc       60

ggcttccact cctggactcg gcctccaccc ctgggcttgg cctcaaagcc tcctcagttg      120

tcggccctgg aaggtgccca gcggcggcag cgccagacgc gccccgttag ctcagcgtcg      180

ctgagcatcc gcagccgcca ccaggccccg cccagcggcc gcagccagcc aggccgcgcc      240

cgggacgact gcagagcgcg gtgctcttac agcctgttcc aagtgtggct taatccgtct      300

ccaccaccag atctttctcc gtggattcct ctgctaagac cgctgccatg ccagtgacgg      360

taacccgcac caccatcaca accaccacga cgtcatcttc gggcctgggg tcccccatga      420

tcgtggggtc ccctcgggcc ctgacacagc ccctgggtct ccttcgcctg ctgcagctgg      480

tgtctacctg cgtggccttc tcgctggtgg ctagcgtggg cgcctggacg gggtccatgg      540

gcaactggtc catgttcacc tggtgcttct gcttctccgt gaccctgatc atcctcatcg      600

tggagctgtg cgggctccag gcccgcttcc ccctgtcttg gcgcaacttc cccatcacct      660

tcgcctgcta tgcggccctc ttctgcctct cggcctccat catctacccc accacctatg      720

tccagttcct gtcccacggc cgttcgcggg accacgccat cgccgccacc ttcttctcct      780

gcatcgcgtg tgtggcttac gccaccgaag tggcctggac ccgggcccgg cccggcgaga      840

tcactggcta tatggccacc gtacccgggc tgctgaaggt gctggagacc ttcgttgcct      900

gcatcatctt cgcgttcatc agcgacccca acctgtacca gcaccagccg gccctggagt      960

ggtgcgtggc ggtgtacgcc atctgcttca tcctagcggc catcgccatc ctgctgaacc     1020

tgggggagtg caccaacgtg ctacccatcc ccttccccag cttcctgtcg gggctggcct     1080

tgctgtctgt cctcctctat gccaccgccc ttgttctctg gcccctctac cagttcgatg     1140

agaagtatgg cggccagcct cggcgctcga gagatgtaag ctgcagccgc agccatgcct     1200

actacgtgtg tgcctgggac cgccgactgg ctgtggccat cctgacggcc atcaacctac     1260

tggcgtatgt ggctgacctg gtgcactctg cccacctggt ttttgtcaag gtctaagact     1320

ctcccaagag gctcccgttc cctctccaac ctctttgttc ttcttgcccg agttttcttt     1380

atggagtact tctttcctcc gcctttcctc tgttttcctc ttcctgtctc ccctccctcc     1440

cacctttttc tttccttccc aattccttgc actctaacca gttcttggat gcatcttctt     1500

ccttcccttt cctcttgctg tttccttcct gtgttgtttt gttgcccaca tcctgttttc     1560

acccctgagc tgtttctctt tttcttttct tttttttttt tttttttttt taagacggat     1620

tctcactctg tggcccaggc tggagtgcag tggtgcgatc tcgactcact gcaacccccg     1680

cctcctgggt tcaagcgatt ctcctgcccc agcctcccaa gtagctggga ggacaggtgt     1740

gagctgccgc acccagcctg tttctctttt tccactcttc ttttttctca tctcttttct     1800

gggttgcctg tcggctttct tatctgcctg ttttgcaagc accttctcct gtgtccttgg     1860

gagccctgag acttctttct ctccttgcct ccacccacct ccaaaggtgc tgagctcaca     1920

tccacacccc ttgcagccgt ccatgccaca gccccccaag gggccccatt gccaaagcat     1980

gcctgcccac cctcgctgtg ccttagtcag tgtgtacgtg tgtgtgtgtg tgtgtgtgtg     2040

tgtgtgtgtt tggggggtgg ggggtgggta gctggggatt gggccctctt tctcccagtg     2100

gaggaaggtg tgcagtgtac ttccccttta aattaaaaaa catatatata tatatatttg     2160

gaggtcagta atttccaatg ggcgggaggc tttaagcacc gaccctgggt ccctaggccc     2220

cgcctggcac tcagccttgc cagagattgg ctccagaatt tttgccaggc ttacagaaca     2280

cccactgcct agaggccatc ttaaaggaag caggggctgg atgcctttca tcccaactat     2340

tctctgtggt atcaaaaaga aaaaaaaaaa aaaagaagga gtcggggccg ggcgtggtgg     2400

ctcacgcctg taatcccagc actttgggag accaagtcag gcaatcatct gaagtcagga     2460

gttcaagacc agcctggcca acatggtgaa agcatgtctc tattaaaaat acaaaaatta     2520

gccgggcgtg gtggcgggcg cctgtaatcc caggtatttg gggggactga gacaggagaa     2580

tcccttcaac ccgggaggtg gaggttgcag taagtcaaga tggcaccact gtgctccagc     2640

ctgggggaca gagcgagact ccatctcaaa aaaaaaaagg aatcggacga agaaccacag     2700

gatgttgaag acaactgtct gaagtatttg tgagggacag cgatgtggcc ctctgtgtta     2760

agaataacgt gtcctgcttt ggcagagaga agaaaatagc cactgcccgc tttcaaggca     2820

agatcgacct tttctgtttt gttttgtttt tctttctttt tcctggccat gaggacaaaa     2880

attactgagt ggcccttaaa gagggaagtt tgttttcagc tgttctcttt tgcccgtagg     2940

tgggagggtg gggattgctg cgtcctagct agaggaatgg ctttgcttga atgtgtagtg     3000

cacacgcacg ggtgtttctg tgtgctagtt gcttcttgct gctgcttcct gcttgtctgg     3060

gactcacata cataacgtga tatatatata tatatatata aatgtataaa tatatatttt     3120

attttttttt aaatccctgg agcttctggt tcctatcagt tcctgttgtt aatcgtagaa     3180

ccgttgtccc ttcccccatt cccgtatcca tcatgttctt tttcttttaa atatcaatat     3240

aaaggtaaaa gaaaaaaaaa aaaaaaaaaa aaaaaa                               3276


<210>  1496
<211>  1216
<212>  DNA
<213>  homo sapiens

<400>  1496
gcccccgcct ggagtccaga cccgacggcc ggcccagttc cacgcaccca gcgagcccaa       60

gcgccttctc cgcaccaggg aagccccacc caccagaagc caagatgtcc agcaagcggg      120

ccaaagccaa gaccaccaag aagcggccac agcgggccac atccaatgtc ttcgcaatgt      180

ttgaccagtc ccagatccag gagtttaagg aggctttcaa catgattgac cagaaccgtg      240

atggcttcat tgacaaggag gacctgcacg acatgctggc ctcgctgggg aagaacccca      300

cagacgaata cctggagggc atgatgagcg aggccccggg gcccatcaac ttcaccatgt      360

tcctcaccat gtttggggag aagctgaacg gcacggaccc cgaggatgtg attcgcaacg      420

cctttgcctg cttcgacgag gaagcctcag gtttcatcca tgaggaccac ctccgggagc      480

tgctcaccac catgggtgac cgcttcacag atgaggaagt ggacgagatg taccgggagg      540

cacccattga taagaaaggc aacttcaact acgtggagtt cacccgcatc ctcaaacatg      600

gcgccaagga taaagacgac taggccaccc cagccccctg acaccccagc ccccgccagt      660

cacccctccc cgcacacacc cgtccatacc agctccctgc ccatgaccct cgctcaggga      720

tccccctttg aggggttagg gtcccagttc ccagtggaag aaacaggcca ggagaagtgc      780

gtgccgagct gaggcagatg ttcccacagt gaccccagag ccctgggcta tagtctctga      840

cccctccaag gaaagaccac cttctgggga catgggctgg agggcaggac ctagaggcac      900

caagggaagg ccccattccg gggctgttcc ccgaggagga agggaagggg ctctgtgtgc      960

cccccaggag gaagaggccc tgagtcctgg gatcagacac cccttcacgt gtatccccac     1020

acaaatgcaa gctcaccaag gtcccctctc agtccccttc cctacaccct gaccggccac     1080

tgccgcacac ccacccagag cacgccaccc gccatgggag tgtgctcagg agtcgcgggc     1140

agcgtggaca tctgtcccag agggggcaga atctccaata gaggactgag cactgctaaa     1200

aaaaaaaaaa aaaaaa                                                     1216


<210>  1497
<211>  3111
<212>  DNA
<213>  homo sapiens

<400>  1497
aaatattctt gcttgagtaa accacagtaa gaataaggaa gtagtgactg agtgccttgc       60

cagtacagca gatgctagaa cataatgtag cattactttc cccagggttt attgttatgt      120

aagttcttgt tcagcttcct ttgttttctt tcacttctga gaatttaact ttcgtttctc      180

actcagctcc tgtggggaaa ctcatttgtg gagaccagcc ctctggcttg gtgagtgaat      240

ctggtttaca ccggctcctg ccctgccttc actcttctcc cctgattcaa gactcctctg      300

ctttggactg aagcactgca ggagtttgtg accaagaact tcaagagtca agacagaagg      360

aagccaaggg agcagtgcaa tggatttctc agtaaaggta gacatagaga aggaggtgac      420

ctgccccatc tgcctggagc tcctgacaga acctctgagc ctagattgtg gccacagctt      480

ctgccaagcc tgcatcactg caaagatcaa ggagtcagtg atcatctcaa gaggggaaag      540

cagctgtcct gtgtgtcaga ccagattcca gcctgggaac ctccgaccta atcggcatct      600

ggccaacata gttgagagag tcaaagaggt caagatgagc ccacaggagg ggcagaagag      660

agatgtctgt gagcaccatg gaaaaaaact ccagatcttc tgtaaggagg atggaaaagt      720

catttgctgg gtttgtgaac tgtctcagga acaccaaggt caccaaacat tccgcataaa      780

cgaggtggtc aaggaatgtc aggaaaagct gcaggtagcc ctgcagaggc tgataaagga      840

ggatcaagag gctgagaagc tggaagatga catcagacaa gagagaaccg cctggaagaa      900

ttatatccag atcgagagac agaagattct gaaagggttc aatgaaatga gagtcatctt      960

ggacaatgag gagcagagag agctgcaaaa gctggaggaa ggtgaggtga atgtgctgga     1020

taacctggca gcagctacag accagctggt ccagcagagg caggatgcca gcacgctcat     1080

ctcagatctc cagcggaggt tgaggggatc gtcagtagag atgctgcagg atgtgattga     1140

cgtcatgaaa aggagtgaaa gctggacatt gaagaagcca aaatctgttt ccaagaaact     1200

aaagagtgta ttccgagtac cagatctgag tgggatgctg caagttctta aagagctgac     1260

agatgtccag tactactggg tggacgtgat gctgaatcca ggcagtgcca cttcgaatgt     1320

tgctatttct gtggatcaga gacaagtgaa aactgtacgc acctgcacat ttaagaattc     1380

aaatccatgt gatttttctg cttttggtgt cttcggctgc caatatttct cttcggggaa     1440

atattactgg gaagtagatg tgtctggaaa gattgcctgg atcctgggcg tacacagtaa     1500

aataagtagt ctgaataaaa ggaagagctc tgggtttgct tttgatccaa gtgtaaatta     1560

ttcaaaagtt tactccagat atagacctca atatggctac tgggttatag gattacagaa     1620

tacatgtgaa tataatgctt ttgaggactc ctcctcttct gatcccaagg ttttgactct     1680

ctttatggct gtgcctccct gtcgtattgg ggttttccta gactatgagg caggcattgt     1740

ctcatttttc aatgtcacaa accacggagc actcatctac aagttctctg gatgtcgctt     1800

ttctcgacct gcttatccgt atttcaatcc ttggaactgc ctagtcccca tgactgtgtg     1860

cccaccgagc tcctgagtgt tctcattcct ttacccactt ctgcatagta gcccttgtgc     1920

tgagactcag attctgcacc tgagttcatc tctactgaga ccatctcttc ctttctttcc     1980

ccttctttta cttagaatgt ctttgtattc atttgctagg gcttccatag caaagcatca     2040

tagattgctg atttaaactg taattgtatt gccgtactgt gggctggaaa tcccaaatct     2100

agattccagc agagttggtt ctttctgagg tctgcaagga agggctctgt tccatgcctc     2160

tctccttggc ttgtagaagg catcttgtcc ctatgactct tcacattgtc tttatgtaca     2220

tctctgtgcc caagttttcc ctttttatta agacaccagt catactggct cagggcccac     2280

cgctaatgcc ttaatgaaat cattttaaca ttatattctc tacaaagacc ttatttccaa     2340

ataagataat atttggaggt attgggaata aaaactccaa catataaatt tgaggaaggc     2400

acgatttcac tcataacaat cttacccttt cttgcaagag atgcttgtac attattttcc     2460

taataccttg gtttcactag tagtaaacat tattattttt tttatatttg caaaggaaac     2520

atatctaatc cttcctatag aaagaacagt attgctgtaa ttccttttct tttcttcctc     2580

atttcctctg ccccttaaaa gattgaagaa agagaaactt gtcaactcat atccacgtta     2640

tctagcaaag tacataagaa tctatcacta agtaatgtat ccttcagaat gtgttggttt     2700

accagtgaca ccccatattc atcacaaaat taaagcaaga agtccatagt aatttatttg     2760

ctaatagtgg atttttaatg ctcagagttt ctgaggtcaa attttatctt ttcacttaca     2820

agctctatga tcttaaataa tttacttaat gtattttggt gtattttcct caaattaata     2880

ttggtgttca agactatatc taattcctct gatcactttg agaaacaaac ttttattaaa     2940

tgtaaggcac ttttctatga attttaaata taaaaataaa tattgttctg attattactg     3000

aaaagatgtc agccatttca atgtcttggg aaacaatttt ttgtttttgt tctgttttct     3060

ttttgcttca ataaaacaat agctggctct aaaaaaaaaa aaaaaaaaaa a              3111


<210>  1498
<211>  8934
<212>  DNA
<213>  homo sapiens

<400>  1498
agtctgtcac acagggacat caccctacag cagttcaggc tgtgtggttc gcaggaagca       60

tacactggct ttttgattct tgctagttcc cagctcacag tttgggagga tccaacacca      120

acctttacgt gaagtggagg cccaaggaca gtgaggagct gggtggtccc agcctggagc      180

tgtgccagcc tgacatggaa atggaggcaa acgaccattt taactttact ggccttcccc      240

ctgcacctgc tgcctcagga ctgaaaccct ctccttcctc aggggagggc ctctacacta      300

acgggtctcc catgaacttc ccccagcaag ggaaaagttt gaatggggat gtgaatgtta      360

atggcttatc tactgtatct cacactacta cttcagggat tttgaactct gctccccact      420

cctccagcac ctcacacctc catcacccca gcgtggccta cgactgtctc tggaactact      480

cacagtaccc atctgccaat cctggcagca acctcaagga cccacccctt ctctcccagt      540

tctcgggggg acaataccca ctcaacggca tccttggggg cagccggcaa ccttcatccc      600

caagtcataa cactaacctt cgggctggga gccaagagtt ctgggccaac ggtacccaga      660

gtcccatggg gcttaacttt gattcacaag aactgtatga ttcctttcct gaccagaatt      720

ttgaggtgat gcccaatgga ccccctagtt ttttcacctc cccacagact tctcctatgt      780

tgggatctag cattcaaacc tttgcaccct cccaggaggt aggcagtggt atccatcctg      840

atgaggcagc agaaaaggag atgacttcag ttgtggcaga gaatggcact ggcttggtag      900

gcagcttgga gctggaagaa gagcagccag aactgaagat gtgtggctac aatggctctg      960

tcccttctgt ggaatcgtta caccaagagg tctcagtcct ggtccctgac cccacagtga     1020

gctgtttaga tgatccttca catcttcctg atcaactgga agacactcca atcctcagtg     1080

aagactctct ggagcccttc aactctctgg caccagagcc agtgagtgga ggactatatg     1140

gtattgatga cacggagctg atgggtgcag aggacaagct gcctcttgag gacagccctg     1200

tgatttctgc ccttgattgc ccttccctca ataatgctac tgccttcagt ctcctggcag     1260

atgatagtca aacatcaacc tctatctttg ccagtcccac ctctccacct gtcctagggg     1320

agtctgtcct gcaagataac agctttgacc tgaataatgg tagtgacgct gaacaggaag     1380

aaatggaaac tcaatcttca gacttcccac catccctgac ccagccagct cctgatcagt     1440

catccactat tcagctacat ccagcaacct caccagcagt ctcgccaaca acctccccag     1500

cagtctccct agtggtttct ccagcagcct ccccagaaat ctctccagaa gtttgtcccg     1560

cagcttctac agttgtctct ccagcagtct tctcagtggt ctctccagct tcctcagcag     1620

tcctcccagc agtctcctta gaagtcccgt tgacggcttc agtgacatcc ccaaaagcct     1680

ctcccgtaac ttccccagca gctgcctttc caacagcctc cccagcaaat aaggatgtca     1740

gcagctttct agaaaccact gctgacgtgg aagagatcac tggagaagga ctcactgctt     1800

ctggtagtgg tgatgtcatg aggagacgta ttgctacccc agaagaagtt cgtcttcccc     1860

tccaacatgg gtggcggaga gaggtgcgca tcaagaaggg cagccaccga tggcaggggg     1920

agacctggta ttatggcccc tgtgggaaga ggatgaagca atttccagaa gtgatcaagt     1980

acctgagccg caacgtggta cacagtgtcc gccgagagca cttcagcttc agtccccgta     2040

tgcctgttgg agatttcttt gaagaaagag acacgccaga gggcttgcag tgggtgcagc     2100

tctcagcaga ggagatcccg tcgaggattc aggcaattac tggcaaacgg ggtcgacctc     2160

gaaacactga gaaggctaag actaaggaag tccccaaggt gaaacggggt cgaggtcggc     2220

cacctaaggt caaaatcact gagctattga acaagacaga caaccgcccc ctaaagaaac     2280

tggaggccca agaaacattg aatgaggagg ataaagcaaa gattgctaaa agcaagaaga     2340

agatgaggca gaaggttcaa cggggagagt gtcagactac tatccaaggg caggccagaa     2400

ataagcggaa acaagagacc aagagcttaa agcagaagga agctaagaag aaatccaagg     2460

ctgagaaaga aaaaggaaag acaaagcagg aaaaactgaa ggaaaaagtc aagagggaaa     2520

agaaggagaa ggtaaaaatg aaggaaaagg aggaggtgac caaagccaag ccagcctgta     2580

aagcagataa gaccctggcc acacagaggc gcttggagga acggcagagg cagcagatga     2640

tcttggagga aatgaagaag ccgacagagg atatgtgtct gactgaccac cagcccctgc     2700

ctgacttctc acgagtccct ggtctgacat tgcccagtgg agccttctca gactgcttga     2760

ccattgtgga gttcctgcat agctttggca aggtgctggg ctttgatcct gccaaagatg     2820

tgcctagcct gggggtcctg caggagggac tcctgtgtca aggtgacagc ttgggtgagg     2880

tgcaagacct gctggtcagg ctgctgaagg ctgcactcca tgatcctggc tttccctcct     2940

actgtcagtc cctaaagatc ttgggggaga aggtgtctga gatcccactg acaagagaca     3000

atgtgtcaga gatcctgcgc tgcttcctta tggcatatgg agtagagcca gccctctgtg     3060

accgcctgcg cacccagcct tttcaggccc agccacccca gcagaaggct gctgtcctgg     3120

ccttccttgt gcatgagctc aatggctcca ccctcatcat caatgagatt gacaagactc     3180

tggagagtat gtccagctac aggaaaaaca agtggattgt tgaaggccgg ctccggaggc     3240

tgaaaactgt tctggccaag cgaactgggc ggtctgaagt agagatggaa gggccagagg     3300

aatgcctggg acggaggcgc agttctcgga tcatggagga gaccagtggc atggaagaag     3360

aggaagaaga ggagtctata gcagctgtcc ctggccgcag gggtcgaaga gatggagagg     3420

ttgatgccac agcatctagc atcccagagc tagagcgcca gatagaaaaa ctcagcaagc     3480

gtcagctttt ctttcgcaaa aagctgcttc actcatccca gatgcttcgg gcggtctccc     3540

tgggtcagga ccgctacaga cgtcgctact gggtattgcc gtatttggct ggtatctttg     3600

tagaaggaac agaggggaac ttagttcctg aggaggtgat aaagaaggaa actgactcct     3660

taaaagtggc agcccatgcg tcactcaacc ctgccctctt ctctatgaag atggagttag     3720

ctggctccaa caccactgcc agttctcctg cccgggcccg aggccgacct cgaaaaacta     3780

agcccgggtc tatgcaacct aggcatctta agtcccctgt caggggtcag gattcagaac     3840

agccccaggc ccagcttcag cctgaggctc agcttcatgc tcctgcccag ccccagcctc     3900

agcttcagct tcagcttcag tcccataagg ggttcctgga gcaagaaggc tcccctttgt     3960

cactgggtca gagccagcat gacctcagcc agtcagcctt cctgtcttgg ctgagccaga     4020

ctcagagcca tagctccctg ttgagcagct cagtcctcac acctgatagc agtccgggaa     4080

aactagaccc agctccatca caacccccgg aggagccaga gcctgatgag gcagaatcca     4140

gccctgatcc tcaagcactc tggtttaaca tctcagccca gatgccctgc aatgctgccc     4200

ccacaccgcc ccctgcagtt tctgaggacc aacccactcc ctcccctcag cagcttgcct     4260

cctccaagcc aatgaataga cctagtgctg ccaacccttg ttctccagtg cagttctctt     4320

ccacgccctt ggctgggttg gcccctaaga ggcgagcagg agaccctgga gaaatgccac     4380

agagtcccac agggctggga cagcccaaac ggagagggag acctcccagt aagttcttca     4440

aacagatgga acagcgttac ctaacccagc tgacagccca gcctgtccca cctgagatgt     4500

gctcaggctg gtggtggata cgagatcctg agatgttgga tgccatgctc aaggccctac     4560

acccccgagg tatccgggag aaggcacttc acaaacacct taacaagcac agggacttct     4620

tgcaggaagt ctgcctgcgg ccctcagctg accccatctt tgagcccagg caactacctg     4680

cctttcaaga agggattatg agctggtccc ccaaagagaa gacatacgag acagacctag     4740

cagtgcttca atgggtagag gagctggagc agcgggttat catgtctgat ctgcagattc     4800

ggggctggac atgtcctagc ccagactcta cccgtgaaga cttggcctac tgtgagcacc     4860

tctccgactc ccaggaggat atcacctggc gaggtcgggg cagggaggga ctggcacctc     4920

agcgtaaaac taccaaccct ttggacctgg ctgtgatgcg gctggctgcc ctggaacaga     4980

atgtagaacg gcggtacctg cgggagcccc tctggccaac tcatgaggtt gtgctggaga     5040

aggccctgct tagcacacct aatggtgccc ctgagggcac cactacagag atatcatatg     5100

agatcacccc tcgcattcgt gtctggcgcc agaccctcga gcggtgccgg agcgcagccc     5160

aggtgtgctt gtgcctgggc cagctggaga ggtccattgc ctgggagaag tctgtcaaca     5220

aagtgacatg tctagtctgc cggaagggtg acaatgatga gtttcttctg ctttgtgatg     5280

ggtgtgaccg tggctgccac atttactgcc atcgtcccaa gatggaggct gtcccagaag     5340

gagattggtt ctgtactgtc tgtttggctc agcaggtgga gggagaattc actcagaagc     5400

ctggtttccc aaagcgtggc cagaagcgga aaagtggtta ttcgctgaac ttctcagagg     5460

gtgatggccg ccgacgccgg gtactgttga ggggccgaga aagcccagca gcagggcctc     5520

ggtactcgga agaagggctc tccccctcca agcggcggcg actctctatg cggaaccacc     5580

acagtgatct cacattttgc gagattatcc tgatggagat ggagtcccat gatgcagcct     5640

ggcctttcct agagcctgtg aacccacgtt tggtgagtgg gtaccggcgc atcatcaaaa     5700

atcctatgga tttttccacc atgcgggagc ggctgctcag gggagggtac accagctcag     5760

aggagtttgc ggctgatgcc ctcctggtat ttgacaactg ccagactttc aacgaggatg     5820

actctgaagt aggcaaggct gggcacatca tgcgccgctt cttcgagagc cgctgggagg     5880

agttttatca gggaaaacag gccaatctgt gaggcaaggg aggtggggag tcaccttgtg     5940

gcatctcccc ccaccttcca aacaaaaacc tgccattttc acctgctgat gctgccctgg     6000

gtccagactc aagtcagata caaccctgat ttttgacctt gcccttggca gtgccccaca     6060

tcctcttatt cctacatccc tttctccctt ccctcctctt gctcctcaag taagaggtgc     6120

agagatgagg tccttctgga ctaaaagcca aaaaaagaaa gaaaaaaata atttttcttt     6180

tctgttttat ttgctaatta aaaatgggga gggggaaagt cgtccctact tcctcctccc     6240

tgcttcctct cctcccctgt acgtgcccca gcattctggg gttatttaac aatagcaata     6300

gttctagtga atgtgtgaaa ccaagaaaca ctctgtactg tgtgcggacc cgcagtgacg     6360

gccagtaaag tggacttaac tcccaagtgt gtcgcgccgg acaccgggcc ctggacatgc     6420

tgcttccatg ttcagtccct tccctgcttc tcgctgtctt tcttttccca cctcccaccc     6480

cccagttttc agattttctc tcatccaata atgtaaaact atcgtgtacg ggttcctccc     6540

tccttttctc ttctcccaaa tcttttccct tcaaaggaaa aaaaaatgtt cagaggtccc     6600

tgtcttctgt ccccatcttc ctgccgatag ctatcccctg tatgatgttg gatgctcctc     6660

acatgctgag tttccagcct tttctgaaac tcagtagctg gggagagggc agggaggctt     6720

cctgggcctt ccagcctcct tccccacctc cttcccaaac cctcttggga actcctcagg     6780

gacaactact gctgagtttg ggtgcaccct aagatggagg ccaggtagca atggggccgg     6840

cctcagagag agcgctgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtcggcctca     6900

gagcgcgctg tgtgtgtgtg tgtgtgtgtc agcctcagag cgcgcgctgt gtgtgtgtgt     6960

gtgtgtgcgt gcttgtgacc ctgtattgtt tgataggatc cattcagttt ccccaagtac     7020

ctgttttcat tcccattttt cccattgttt aaaaccatca cttttttgtc tttgggaaac     7080

cacaggaaca atttctctgg agacaaggct gtgtctctct cctggtcatt tttgttccag     7140

cctcttcaga ctgtgcaatc tttcagcagg aactccctct cttctcggta gctttgaatc     7200

ttaagcttct acgggagagt ggtagaactg gatcatttcc taatcccatt tagttgtgct     7260

tttcttcatt tacttcatac cccaggaccc cttccccagc agcagagacc ctggagcaca     7320

ggagagtagg gaggaggggt tctgggtcca tcactgccct acatgtgact atgtccaagt     7380

taagccccca acacgagagg aaagctgctg actcccagct atagccatgg gcacttggcc     7440

ccctgctttt cctgctcagc agagcccctc ccttcagaga ttacgggtac ttgcactggg     7500

gaggtggctg ctggctggcc caagcagaga gctgaggcat ccaagaaatg ttccattggg     7560

gggtgggggt gccaggtgag gtggagcatt ccttgtattc tggcagcact gaagagccac     7620

tgaagggggt aggggcagtg taggtcctgg ggcagcccct ttattccttt atgccccttc     7680

tccctcatag cctatttcta aagtcgcctt ttctgtcaga taaacctcaa aacttttaat     7740

tttatttgag attttttttt gcttttaaga ggtggattga agaatatttg aattgacttt     7800

atattatgca taaatattta tattttatct aaataactgc gctgtaacaa actttgtgtt     7860

agacagttga aactgttaga gttgggggct ctgctttttc cccctggcaa ttttcccctg     7920

gtataagatg tgctagatta atttcattgt gaggtggatg ggggagtgaa attgtgaggt     7980

ggatggggga gtgaaatctc catggttcct gctttgtgtt cctctcccag ctccatctct     8040

ttccctaggg accaggcact catatggcgg ggtggggtcc tagcctcagt ttgaagaagt     8100

gggggctgga gcggggttgg gggtggtagg gatagggcat gatcaaaggg gccatttctt     8160

gcttttcttt cctcatcttc actgccccct tgagctaggt ggattttctc ttcatgacaa     8220

gagtatttgg tagggaaagc aggtttaaaa taaaaagaca acccaccccc tgcccttttg     8280

cttccctccc atcagtctgg ttgacaggaa gaaaccacac catcaacacc aacaagtttc     8340

tgtgttcctt ttacagcaaa agggactttt tatataacca aatgtggtgt tttagtgact     8400

ttttgataat gtacagtttt ttgtgaattt aaatttattt ctttctatat ttttaggacc     8460

aatctcattt ttaataaggt taaaaagaaa aaaaaagtct agcgaaaaaa ctcctgtttt     8520

tgccatgtga tgttccacaa gtgcagctgt agaaaagtgc ttgtcagttg ttgaataaaa     8580

aaaaccacat ttgatagaga ttcaaaagac tctgtgtatt catcttccct tctacacacc     8640

tgagggggag acggcgttgg gataggtatg actggcttaa gagaccacag gcaagggaac     8700

aacaggggct cctgttccat accctctgtg tggatggaaa gggtcattag tgctcctgcc     8760

taaatgtctg gctgagttgc tggagcaaag ggggattcag tgcatccagg tcctgccttg     8820

tgagatgtgg ccccagcttc ctaagctgcc acctctgtgt tcctgtcata gcaaatatgg     8880

gaccatcacc agcttaccac ttcccactca cggataagac accaagacgt agac           8934


<210>  1499
<211>  2797
<212>  DNA
<213>  homo sapiens

<400>  1499
tcccgcccgc gccctgccca ccccggccgc gcgcaccaca acgcccccgc cccgccgccc       60

ggaaccagct gagcgcagct ggacccagca gccgctgtct ccagtgccgc agcagcaggt      120

agtgctcata gctctctttg tccagtgctt cggccttggt cccagcgcct tcccacggag      180

cagcactctt caccctgcac agccttgtta ggagaagggg atgaatgaat acaggactta      240

cgcgtctgct gtggcccagc tggcttccag atggtgacat gagccaccca cagccggagc      300

tgttcctctt tcccaaagct cagcccaaca gcatggtggt ggaacacccc gagttcctca      360

aggcagggaa ggagcctggc ctgcagatct ggcgtgtgga gaagttcgat ctggtgcccg      420

tgcccaccaa cctttatgga gacttcttca cgggcgacgc ctacgtcatc ctgaagacag      480

tgcagctgag gaacggaaat ctgcagtatg acctccacta ctggctgggc aatgagtgca      540

gccaggatga gagcggggcg gccgccatct ttaccgtgca gctggatgac tacctgaacg      600

gccgggccgt gcagcaccgt gaggtccagg gcttcgagtc ggccaccttc ctaggctact      660

tcaagtctgg cctgaagtac aagaaaggag gtgtggcatc aggattcaag cacgtggtac      720

ccaacgaggt ggtggtgcag agactcttcc aggtcaaagg gcggcgtgtg gtccgtgcca      780

ccgaggtacc tgtgtcctgg gagagcttca acaatggcga ctgcttcatc ctggacctgg      840

gcaacaacat ccaccagtgg tgtggttcca acagcaatcg gtatgaaaga ctgaaggcca      900

cacaggtgtc caagggcatc cgggacaacg agcggagtgg ccgggcccga gtgcacgtgt      960

ctgaggaggg cactgagccc gaggcgatgc tccaggtgct gggccccaag ccggctctgc     1020

ctgcaggtac cgaggacacc gccaaggagg atgcggccaa ccgcaagctg gccaagctct     1080

acaaggtctc caatggtgca gggaccatgt ccgtctccct cgtggctgat gagaacccct     1140

tcgcccaggg ggccctgaag tcagaggact gcttcatcct ggaccacggc aaagatggga     1200

aaatctttgt ctggaaaggc aagcaggcaa acacggagga gaggaaggct gccctcaaaa     1260

cagcctctga cttcatcacc aagatggact accccaagca gactcaggtc tcggtccttc     1320

ctgagggcgg tgagacccca ctgttcaagc agttcttcaa gaactggcgg gacccagacc     1380

agacagatgg cctgggcttg tcctaccttt ccagccatat cgccaacgtg gagcgggtgc     1440

ccttcgacgc cgccaccctg cacacctcca ctgccatggc cgcccagcac ggcatggatg     1500

acgatggcac aggccagaaa cagatctgga gaatcgaagg ttccaacaag gtgcccgtgg     1560

accctgccac atatggacag ttctatggag gcgacagcta catcattctg tacaactacc     1620

gccatggtgg ccgccagggg cagataatct ataactggca gggtgcccag tctacccagg     1680

atgaggtcgc tgcatctgcc atcctgactg ctcagctgga tgaggagctg ggaggtaccc     1740

ctgtccagag ccgtgtggtc caaggcaagg agcccgccca cctcatgagc ctgtttggtg     1800

ggaagcccat gatcatctac aagggcggca cctcccgcga gggcgggcag acagcccctg     1860

ccagcacccg cctcttccag gtccgcgcca acagcgctgg agccacccgg gctgttgagg     1920

tattgcctaa ggctggtgca ctgaactcca acgatgcctt tgttctgaaa accccctcag     1980

ccgcctacct gtgggtgggt acaggagcca gcgaggcaga gaagacgggg gcccaggagc     2040

tgctcagggt gctgcgggcc caacctgtgc aggtggcaga aggcagcgag ccagatggct     2100

tctgggaggc cctgggcggg aaggctgcct accgcacatc cccacggctg aaggacaaga     2160

agatggatgc ccatcctcct cgcctctttg cctgctccaa caagattgga cgttttgtga     2220

tcgaagaggt tcctggtgag ctcatgcagg aagacctggc aacggatgac gtcatgcttc     2280

tggacacctg ggaccaggtc tttgtctggg ttggaaagga ttctcaagaa gaagaaaaga     2340

cagaagcctt gacttctgct aagcggtaca tcgagacgga cccagccaat cgggatcggc     2400

ggacgcccat caccgtggtg aagcaaggct ttgagcctcc ctcctttgtg ggctggttcc     2460

ttggctggga tgatgattac tggtctgtgg accccttgga cagggccatg gctgagctgg     2520

ctgcctgagg aggggcaggg cccacccatg tcaccggtca gtgccttttg gaactgtcct     2580

tccctcaaag aggccttaga gcgagcagag cagctctgct atgagtgtgt gtgtgtgtgt     2640

gtgttgtttc tttttttttt ttttacagta tccaaaaata gccctgcaaa aattcagagt     2700

ccttgcaaaa ttgtctaaaa tgtcagtgtt tgggaaatta aatccaataa aaacattttg     2760

aagtgtgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa                              2797


<210>  1500
<211>  2764
<212>  DNA
<213>  homo sapiens

<400>  1500
tcccgcccgc gccctgccca ccccggccgc gcgcaccaca acgcccccgc cccgccgccc       60

ggaaccagct gagcgcagct ggacccagca gccgctgtct ccagtgccgc agcagcaggt      120

agtgctcata gctctctttg tccagtgctt cggccttggt cccagcgcct tcccacggag      180

cagcactctt caccctgcac agccttgtta ggccttggtt gctattctgt agaagagcag      240

agtccccata aagaggaggt gcaggaattc ttcccagagg ctttggagag cccaacagca      300

tggtggtgga acaccccgag ttcctcaagg cagggaagga gcctggcctg cagatctggc      360

gtgtggagaa gttcgatctg gtgcccgtgc ccaccaacct ttatggagac ttcttcacgg      420

gcgacgccta cgtcatcctg aagacagtgc agctgaggaa cggaaatctg cagtatgacc      480

tccactactg gctgggcaat gagtgcagcc aggatgagag cggggcggcc gccatcttta      540

ccgtgcagct ggatgactac ctgaacggcc gggccgtgca gcaccgtgag gtccagggct      600

tcgagtcggc caccttccta ggctacttca agtctggcct gaagtacaag aaaggaggtg      660

tggcatcagg attcaagcac gtggtaccca acgaggtggt ggtgcagaga ctcttccagg      720

tcaaagggcg gcgtgtggtc cgtgccaccg aggtacctgt gtcctgggag agcttcaaca      780

atggcgactg cttcatcctg gacctgggca acaacatcca ccagtggtgt ggttccaaca      840

gcaatcggta tgaaagactg aaggccacac aggtgtccaa gggcatccgg gacaacgagc      900

ggagtggccg ggcccgagtg cacgtgtctg aggagggcac tgagcccgag gcgatgctcc      960

aggtgctggg ccccaagccg gctctgcctg caggtaccga ggacaccgcc aaggaggatg     1020

cggccaaccg caagctggcc aagctctaca aggtctccaa tggtgcaggg accatgtccg     1080

tctccctcgt ggctgatgag aaccccttcg cccagggggc cctgaagtca gaggactgct     1140

tcatcctgga ccacggcaaa gatgggaaaa tctttgtctg gaaaggcaag caggcaaaca     1200

cggaggagag gaaggctgcc ctcaaaacag cctctgactt catcaccaag atggactacc     1260

ccaagcagac tcaggtctcg gtccttcctg agggcggtga gaccccactg ttcaagcagt     1320

tcttcaagaa ctggcgggac ccagaccaga cagatggcct gggcttgtcc tacctttcca     1380

gccatatcgc caacgtggag cgggtgccct tcgacgccgc caccctgcac acctccactg     1440

ccatggccgc ccagcacggc atggatgacg atggcacagg ccagaaacag atctggagaa     1500

tcgaaggttc caacaaggtg cccgtggacc ctgccacata tggacagttc tatggaggcg     1560

acagctacat cattctgtac aactaccgcc atggtggccg ccaggggcag ataatctata     1620

actggcaggg tgcccagtct acccaggatg aggtcgctgc atctgccatc ctgactgctc     1680

agctggatga ggagctggga ggtacccctg tccagagccg tgtggtccaa ggcaaggagc     1740

ccgcccacct catgagcctg tttggtggga agcccatgat catctacaag ggcggcacct     1800

cccgcgaggg cgggcagaca gcccctgcca gcacccgcct cttccaggtc cgcgccaaca     1860

gcgctggagc cacccgggct gttgaggtat tgcctaaggc tggtgcactg aactccaacg     1920

atgcctttgt tctgaaaacc ccctcagccg cctacctgtg ggtgggtaca ggagccagcg     1980

aggcagagaa gacgggggcc caggagctgc tcagggtgct gcgggcccaa cctgtgcagg     2040

tggcagaagg cagcgagcca gatggcttct gggaggccct gggcgggaag gctgcctacc     2100

gcacatcccc acggctgaag gacaagaaga tggatgccca tcctcctcgc ctctttgcct     2160

gctccaacaa gattggacgt tttgtgatcg aagaggttcc tggtgagctc atgcaggaag     2220

acctggcaac ggatgacgtc atgcttctgg acacctggga ccaggtcttt gtctgggttg     2280

gaaaggattc tcaagaagaa gaaaagacag aagccttgac ttctgctaag cggtacatcg     2340

agacggaccc agccaatcgg gatcggcgga cgcccatcac cgtggtgaag caaggctttg     2400

agcctccctc ctttgtgggc tggttccttg gctgggatga tgattactgg tctgtggacc     2460

ccttggacag ggccatggct gagctggctg cctgaggagg ggcagggccc acccatgtca     2520

ccggtcagtg ccttttggaa ctgtccttcc ctcaaagagg ccttagagcg agcagagcag     2580

ctctgctatg agtgtgtgtg tgtgtgtgtg ttgtttcttt tttttttttt tacagtatcc     2640

aaaaatagcc ctgcaaaaat tcagagtcct tgcaaaattg tctaaaatgt cagtgtttgg     2700

gaaattaaat ccaataaaaa cattttgaag tgtgaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaa                                                                  2764


<210>  1501
<211>  2759
<212>  DNA
<213>  homo sapiens

<400>  1501
tcccgcccgc gccctgccca ccccggccgc gcgcaccaca acgcccccgc cccgccgccc       60

ggaaccagct gagcgcagct ggacccagca gccgctgtct ccagtgccgc agcagcaggt      120

agtgctcata gctctctttg tccagtgctt cggccttggt cccagcgcct tcccacggag      180

cagcactctt caccctgcac agccttgtta gacggagtct tgctgtggtg cccaggctgg      240

agtgcagtgg cacgatctca gctcactgca acctcctcct cccagcccaa cagcatggtg      300

gtggaacacc ccgagttcct caaggcaggg aaggagcctg gcctgcagat ctggcgtgtg      360

gagaagttcg atctggtgcc cgtgcccacc aacctttatg gagacttctt cacgggcgac      420

gcctacgtca tcctgaagac agtgcagctg aggaacggaa atctgcagta tgacctccac      480

tactggctgg gcaatgagtg cagccaggat gagagcgggg cggccgccat ctttaccgtg      540

cagctggatg actacctgaa cggccgggcc gtgcagcacc gtgaggtcca gggcttcgag      600

tcggccacct tcctaggcta cttcaagtct ggcctgaagt acaagaaagg aggtgtggca      660

tcaggattca agcacgtggt acccaacgag gtggtggtgc agagactctt ccaggtcaaa      720

gggcggcgtg tggtccgtgc caccgaggta cctgtgtcct gggagagctt caacaatggc      780

gactgcttca tcctggacct gggcaacaac atccaccagt ggtgtggttc caacagcaat      840

cggtatgaaa gactgaaggc cacacaggtg tccaagggca tccgggacaa cgagcggagt      900

ggccgggccc gagtgcacgt gtctgaggag ggcactgagc ccgaggcgat gctccaggtg      960

ctgggcccca agccggctct gcctgcaggt accgaggaca ccgccaagga ggatgcggcc     1020

aaccgcaagc tggccaagct ctacaaggtc tccaatggtg cagggaccat gtccgtctcc     1080

ctcgtggctg atgagaaccc cttcgcccag ggggccctga agtcagagga ctgcttcatc     1140

ctggaccacg gcaaagatgg gaaaatcttt gtctggaaag gcaagcaggc aaacacggag     1200

gagaggaagg ctgccctcaa aacagcctct gacttcatca ccaagatgga ctaccccaag     1260

cagactcagg tctcggtcct tcctgagggc ggtgagaccc cactgttcaa gcagttcttc     1320

aagaactggc gggacccaga ccagacagat ggcctgggct tgtcctacct ttccagccat     1380

atcgccaacg tggagcgggt gcccttcgac gccgccaccc tgcacacctc cactgccatg     1440

gccgcccagc acggcatgga tgacgatggc acaggccaga aacagatctg gagaatcgaa     1500

ggttccaaca aggtgcccgt ggaccctgcc acatatggac agttctatgg aggcgacagc     1560

tacatcattc tgtacaacta ccgccatggt ggccgccagg ggcagataat ctataactgg     1620

cagggtgccc agtctaccca ggatgaggtc gctgcatctg ccatcctgac tgctcagctg     1680

gatgaggagc tgggaggtac ccctgtccag agccgtgtgg tccaaggcaa ggagcccgcc     1740

cacctcatga gcctgtttgg tgggaagccc atgatcatct acaagggcgg cacctcccgc     1800

gagggcgggc agacagcccc tgccagcacc cgcctcttcc aggtccgcgc caacagcgct     1860

ggagccaccc gggctgttga ggtattgcct aaggctggtg cactgaactc caacgatgcc     1920

tttgttctga aaaccccctc agccgcctac ctgtgggtgg gtacaggagc cagcgaggca     1980

gagaagacgg gggcccagga gctgctcagg gtgctgcggg cccaacctgt gcaggtggca     2040

gaaggcagcg agccagatgg cttctgggag gccctgggcg ggaaggctgc ctaccgcaca     2100

tccccacggc tgaaggacaa gaagatggat gcccatcctc ctcgcctctt tgcctgctcc     2160

aacaagattg gacgttttgt gatcgaagag gttcctggtg agctcatgca ggaagacctg     2220

gcaacggatg acgtcatgct tctggacacc tgggaccagg tctttgtctg ggttggaaag     2280

gattctcaag aagaagaaaa gacagaagcc ttgacttctg ctaagcggta catcgagacg     2340

gacccagcca atcgggatcg gcggacgccc atcaccgtgg tgaagcaagg ctttgagcct     2400

ccctcctttg tgggctggtt ccttggctgg gatgatgatt actggtctgt ggaccccttg     2460

gacagggcca tggctgagct ggctgcctga ggaggggcag ggcccaccca tgtcaccggt     2520

cagtgccttt tggaactgtc cttccctcaa agaggcctta gagcgagcag agcagctctg     2580

ctatgagtgt gtgtgtgtgt gtgtgttgtt tctttttttt ttttttacag tatccaaaaa     2640

tagccctgca aaaattcaga gtccttgcaa aattgtctaa aatgtcagtg tttgggaaat     2700

taaatccaat aaaaacattt tgaagtgtga aaaaaaaaaa aaaaaaaaaa aaaaaaaaa      2759


<210>  1502
<211>  2756
<212>  DNA
<213>  homo sapiens

<400>  1502
tcccgcccgc gccctgccca ccccggccgc gcgcaccaca acgcccccgc cccgccgccc       60

ggaaccagct gagcgcagct ggacccagca gccgctgtct ccagtgccgc agcagcaggt      120

agtgctcata gctctctttg tccagtgctt cggccttggt cccagcgcct tcccacggag      180

cagcactctt caccctgcac agccttgtta gttcttgcag atacagcgct aggaaaaggg      240

gagtaattca ggtctagaat ggaaaaactg ttttgttgct ttcccaacag catggtggtg      300

gaacaccccg agttcctcaa ggcagggaag gagcctggcc tgcagatctg gcgtgtggag      360

aagttcgatc tggtgcccgt gcccaccaac ctttatggag acttcttcac gggcgacgcc      420

tacgtcatcc tgaagacagt gcagctgagg aacggaaatc tgcagtatga cctccactac      480

tggctgggca atgagtgcag ccaggatgag agcggggcgg ccgccatctt taccgtgcag      540

ctggatgact acctgaacgg ccgggccgtg cagcaccgtg aggtccaggg cttcgagtcg      600

gccaccttcc taggctactt caagtctggc ctgaagtaca agaaaggagg tgtggcatca      660

ggattcaagc acgtggtacc caacgaggtg gtggtgcaga gactcttcca ggtcaaaggg      720

cggcgtgtgg tccgtgccac cgaggtacct gtgtcctggg agagcttcaa caatggcgac      780

tgcttcatcc tggacctggg caacaacatc caccagtggt gtggttccaa cagcaatcgg      840

tatgaaagac tgaaggccac acaggtgtcc aagggcatcc gggacaacga gcggagtggc      900

cgggcccgag tgcacgtgtc tgaggagggc actgagcccg aggcgatgct ccaggtgctg      960

ggccccaagc cggctctgcc tgcaggtacc gaggacaccg ccaaggagga tgcggccaac     1020

cgcaagctgg ccaagctcta caaggtctcc aatggtgcag ggaccatgtc cgtctccctc     1080

gtggctgatg agaacccctt cgcccagggg gccctgaagt cagaggactg cttcatcctg     1140

gaccacggca aagatgggaa aatctttgtc tggaaaggca agcaggcaaa cacggaggag     1200

aggaaggctg ccctcaaaac agcctctgac ttcatcacca agatggacta ccccaagcag     1260

actcaggtct cggtccttcc tgagggcggt gagaccccac tgttcaagca gttcttcaag     1320

aactggcggg acccagacca gacagatggc ctgggcttgt cctacctttc cagccatatc     1380

gccaacgtgg agcgggtgcc cttcgacgcc gccaccctgc acacctccac tgccatggcc     1440

gcccagcacg gcatggatga cgatggcaca ggccagaaac agatctggag aatcgaaggt     1500

tccaacaagg tgcccgtgga ccctgccaca tatggacagt tctatggagg cgacagctac     1560

atcattctgt acaactaccg ccatggtggc cgccaggggc agataatcta taactggcag     1620

ggtgcccagt ctacccagga tgaggtcgct gcatctgcca tcctgactgc tcagctggat     1680

gaggagctgg gaggtacccc tgtccagagc cgtgtggtcc aaggcaagga gcccgcccac     1740

ctcatgagcc tgtttggtgg gaagcccatg atcatctaca agggcggcac ctcccgcgag     1800

ggcgggcaga cagcccctgc cagcacccgc ctcttccagg tccgcgccaa cagcgctgga     1860

gccacccggg ctgttgaggt attgcctaag gctggtgcac tgaactccaa cgatgccttt     1920

gttctgaaaa ccccctcagc cgcctacctg tgggtgggta caggagccag cgaggcagag     1980

aagacggggg cccaggagct gctcagggtg ctgcgggccc aacctgtgca ggtggcagaa     2040

ggcagcgagc cagatggctt ctgggaggcc ctgggcggga aggctgccta ccgcacatcc     2100

ccacggctga aggacaagaa gatggatgcc catcctcctc gcctctttgc ctgctccaac     2160

aagattggac gttttgtgat cgaagaggtt cctggtgagc tcatgcagga agacctggca     2220

acggatgacg tcatgcttct ggacacctgg gaccaggtct ttgtctgggt tggaaaggat     2280

tctcaagaag aagaaaagac agaagccttg acttctgcta agcggtacat cgagacggac     2340

ccagccaatc gggatcggcg gacgcccatc accgtggtga agcaaggctt tgagcctccc     2400

tcctttgtgg gctggttcct tggctgggat gatgattact ggtctgtgga ccccttggac     2460

agggccatgg ctgagctggc tgcctgagga ggggcagggc ccacccatgt caccggtcag     2520

tgccttttgg aactgtcctt ccctcaaaga ggccttagag cgagcagagc agctctgcta     2580

tgagtgtgtg tgtgtgtgtg tgttgtttct tttttttttt tttacagtat ccaaaaatag     2640

ccctgcaaaa attcagagtc cttgcaaaat tgtctaaaat gtcagtgttt gggaaattaa     2700

atccaataaa aacattttga agtgtgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa         2756


<210>  1503
<211>  2747
<212>  DNA
<213>  homo sapiens

<400>  1503
tcccgcccgc gccctgccca ccccggccgc gcgcaccaca acgcccccgc cccgccgccc       60

ggaaccagct gagcgcagct ggacccagca gccgctgtct ccagtgccgc agcagcaggt      120

agtgctcata gctctctttg tccagtgctt cggccttggt cccagcgcct tcccacggag      180

cagcactctt caccctgcac agccttgtta gatacagcgc taggaaaagg ggagtaattc      240

aggtctagaa tggaaaaact gttttgttgc tttcccaaca gcatggtggt ggaacacccc      300

gagttcctca aggcagggaa ggagcctggc ctgcagatct ggcgtgtgga gaagttcgat      360

ctggtgcccg tgcccaccaa cctttatgga gacttcttca cgggcgacgc ctacgtcatc      420

ctgaagacag tgcagctgag gaacggaaat ctgcagtatg acctccacta ctggctgggc      480

aatgagtgca gccaggatga gagcggggcg gccgccatct ttaccgtgca gctggatgac      540

tacctgaacg gccgggccgt gcagcaccgt gaggtccagg gcttcgagtc ggccaccttc      600

ctaggctact tcaagtctgg cctgaagtac aagaaaggag gtgtggcatc aggattcaag      660

cacgtggtac ccaacgaggt ggtggtgcag agactcttcc aggtcaaagg gcggcgtgtg      720

gtccgtgcca ccgaggtacc tgtgtcctgg gagagcttca acaatggcga ctgcttcatc      780

ctggacctgg gcaacaacat ccaccagtgg tgtggttcca acagcaatcg gtatgaaaga      840

ctgaaggcca cacaggtgtc caagggcatc cgggacaacg agcggagtgg ccgggcccga      900

gtgcacgtgt ctgaggaggg cactgagccc gaggcgatgc tccaggtgct gggccccaag      960

ccggctctgc ctgcaggtac cgaggacacc gccaaggagg atgcggccaa ccgcaagctg     1020

gccaagctct acaaggtctc caatggtgca gggaccatgt ccgtctccct cgtggctgat     1080

gagaacccct tcgcccaggg ggccctgaag tcagaggact gcttcatcct ggaccacggc     1140

aaagatggga aaatctttgt ctggaaaggc aagcaggcaa acacggagga gaggaaggct     1200

gccctcaaaa cagcctctga cttcatcacc aagatggact accccaagca gactcaggtc     1260

tcggtccttc ctgagggcgg tgagacccca ctgttcaagc agttcttcaa gaactggcgg     1320

gacccagacc agacagatgg cctgggcttg tcctaccttt ccagccatat cgccaacgtg     1380

gagcgggtgc ccttcgacgc cgccaccctg cacacctcca ctgccatggc cgcccagcac     1440

ggcatggatg acgatggcac aggccagaaa cagatctgga gaatcgaagg ttccaacaag     1500

gtgcccgtgg accctgccac atatggacag ttctatggag gcgacagcta catcattctg     1560

tacaactacc gccatggtgg ccgccagggg cagataatct ataactggca gggtgcccag     1620

tctacccagg atgaggtcgc tgcatctgcc atcctgactg ctcagctgga tgaggagctg     1680

ggaggtaccc ctgtccagag ccgtgtggtc caaggcaagg agcccgccca cctcatgagc     1740

ctgtttggtg ggaagcccat gatcatctac aagggcggca cctcccgcga gggcgggcag     1800

acagcccctg ccagcacccg cctcttccag gtccgcgcca acagcgctgg agccacccgg     1860

gctgttgagg tattgcctaa ggctggtgca ctgaactcca acgatgcctt tgttctgaaa     1920

accccctcag ccgcctacct gtgggtgggt acaggagcca gcgaggcaga gaagacgggg     1980

gcccaggagc tgctcagggt gctgcgggcc caacctgtgc aggtggcaga aggcagcgag     2040

ccagatggct tctgggaggc cctgggcggg aaggctgcct accgcacatc cccacggctg     2100

aaggacaaga agatggatgc ccatcctcct cgcctctttg cctgctccaa caagattgga     2160

cgttttgtga tcgaagaggt tcctggtgag ctcatgcagg aagacctggc aacggatgac     2220

gtcatgcttc tggacacctg ggaccaggtc tttgtctggg ttggaaagga ttctcaagaa     2280

gaagaaaaga cagaagcctt gacttctgct aagcggtaca tcgagacgga cccagccaat     2340

cgggatcggc ggacgcccat caccgtggtg aagcaaggct ttgagcctcc ctcctttgtg     2400

ggctggttcc ttggctggga tgatgattac tggtctgtgg accccttgga cagggccatg     2460

gctgagctgg ctgcctgagg aggggcaggg cccacccatg tcaccggtca gtgccttttg     2520

gaactgtcct tccctcaaag aggccttaga gcgagcagag cagctctgct atgagtgtgt     2580

gtgtgtgtgt gtgttgtttc tttttttttt ttttacagta tccaaaaata gccctgcaaa     2640

aattcagagt ccttgcaaaa ttgtctaaaa tgtcagtgtt tgggaaatta aatccaataa     2700

aaacattttg aagtgtgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa                   2747


<210>  1504
<211>  5338
<212>  DNA
<213>  homo sapiens

<400>  1504
gagggaaggc gcgcagacgc gcagcggccg gcctgctccg ggcgcgtcag gcagggggtg       60

gggagcaggg gccgggcggg cgctcggctc ccagccgcgc tccctcgggc cactagcgct      120

cccgcgcgcg cccggccgcc ttcatgtgaa gcgccggccc tccgcccctt ccctcccctt      180

ccttccctcc ctccctccct gtcccctcct cctcctcctc ctcctccggc gcccgcttca      240

gctccccggg gccccctgcc cggccgggcg ctgacagcaa gggcgggggt ccctgccgcc      300

gccttgtctc gcgcagggtc cggctggggt agcggagccc ccagtgcggc catggaccgg      360

cccctgtcgt cgtcggcgga ggcggaggag gaactggagt ggcaagtggc gagtcgcagg      420

aggaaggcct gggccaagtg ccgcagctcc tggcaagcgt cggagacgga ggatctgtcc      480

acagaagcga cgacgcagga cgaggaggag gacgaggagg aggacctccc cggcgcgcag      540

ctgccggcag cggggggaag aggaaacgtg cccaacgaga agatcgcgat atggctcaag      600

gactgccgta cacctttggg agcctcactg gatgaacaaa gcagtagtac actcaagggt      660

gtgcttgtga gaaatggagg aagttttgaa gatgatttgt cattgggagc tgaagccaac      720

cacctccatg aaagtgatgc tcaaattgaa aactgcaata atatcttggc caaagagaga      780

agattacagt ttcatcagaa agggagaagt atgaattcca ctggatctgg gaaaagtagt      840

gggacagttt caagtgtttc agaattgttg gaactttatg aggaagatcc tgaagaaatt      900

ctttataatc ttggatttgg acgtgatgaa ccagatattg cttctaaaat tccttccaga      960

ttttttaatt catcatcctt tgccaaaggg atagatatta aagtattttt gagtgctcag     1020

atgcaacgga tggaagtaga aaacccaaat tatgctttaa caagccgttt tcgtcaaatt     1080

gaagtgctta ctactgtggc caatgcgttt tcttctttat attctcaagt ctccgggacg     1140

cccctgcaga gaattggaag tatgtcctca gtgacctcta acaaggagac agacccacct     1200

ccacctttaa ctcgaagtaa cactgcaaat cgtttaatga aaacactctc aaaactgaat     1260

ttatgtgttg ataaaacaga gaaaggagaa agtagtagtc cttctccatc agctgaaaaa     1320

ggaaagattc taaatgtttc agtgattgaa gaaagtggca ataaaaacga tcaaaagtct     1380

caaaaaatta tgaagaagaa agagtcatct tctatgttgg ctacagttaa agaagaagtc     1440

tctggtagtt cagcagctgt tacggagaat gctgatagtg atagaatttc tgatgaagca     1500

aatagtaatt ttaaccaagg aactgaaaat gaacaaagta aagaaactca aagtcatgag     1560

agtaaactgg gtgaggaatc tggtattgta gaatccaaat tagatagtga tttcaacata     1620

tccagccaca gtgagctgga aaatagcagt gagctgaaaa gtgtccatat atccacacct     1680

gaaaaagagc cttgtgcacc actgacaata ccatccataa gaaatataat gacacagcag     1740

aaggactcct tcgaaatgga agaggttcaa agtacggagg gagaagctcc tcatgttcca     1800

gccacttacc agctaggtct tacgaagtcg aaaagagatc atctgttacg tactgcaagt     1860

cagcattccg atagcagtgg ttttgctgaa gattctacag actgcctatc ccttaatcat     1920

cttcaggttc aggagtcctt gcaggctatg gggagtagtg ctgatagttg tgacagtgag     1980

acaacagtta cgtcacttgg tgaagacctt gccacaccaa cagcacaaga ccagccttat     2040

tttaatgaat cagaggagga gtctcttgtc cctcttcaga agggactaga gaaggcagca     2100

gcagttgcag acaaaagaaa atcaggtagc caggatttcc ctcagtgcaa caccattgag     2160

aatacaggaa ctaaacagtc cacctgtagt ccaggggatc atatcattga aattactgaa     2220

gtggaagagg atttgtttcc agcagagaca gtagagctac tgagggaagc aagtgctgaa     2280

agtgatgtgg gtaaaagcag tgaaagtgaa tttactcagt ataccacaca ccatattctg     2340

aaatcattgg cttctattga agctaaatgc agtgatatga gctctgaaaa tacaactggg     2400

cctccctctt ccatggacag agttaataca gctttgcaaa gagctcaaat gaaggtttgc     2460

agtctgtcta atcaaaggat ggggcgtagc ctgctaaaat caaaagattt gttaaaacaa     2520

aggtacttat ttgcaaaagc tggctatcct ctaagaaggt ctcagtcttt accaaccacc     2580

ttattgagcc cagtaagggt tgtgtcctct gtcaatgttc gattatctcc aggaaaagag     2640

accagatgca gcccaccttc cttcacctat aagtacacac ctgaagagga gcaggaattg     2700

gaaaagcggg tgatggaaca tgatggtcag tctttagtta aatcgaccat tttcatctct     2760

ccatcatctg tgaagaaaga agaagccccc cagagtgagg cgccgcgggt ggaggaatgc     2820

catcatggaa ggactcctac ctgttcacgg cttgctccac caccaatgtc tcagtctacc     2880

tgttcccttc attccatcca ctctgagtgg caagaaaggc ccctgtgtga gcacacaaga     2940

actctgagca ctcacagtgt tcccaacata tcaggggcta cttgtagtgc cttcgcttcc     3000

cctttcgggt gtccttactc acatagacat gccacctacc cttaccgagt gtgctctgtg     3060

aatcctcctt cagccataga aatgcagttg cgaagagtat tacatgatat tagaaactca     3120

ctgcagaatc tttcacagta ccctatgatg agaggacctg atcctgctgc tgctccatat     3180

agtactcaga aatcatctgt tctacctctt tatgaaaata cttttcagga gctccaggta     3240

atgaggcgga gcctgaattt gtttagaaca caaatgatgg atttagaatt ggcaatgctg     3300

cgtcagcaaa ccatggttta tcatcatatg actgaggagg agaggtttga agttgatcag     3360

ctccagggtt tgagaaattc agtccgaatg gaacttcagg acctggaact gcagctggag     3420

gagcgcctgc tgggcctgga ggagcagctt cgtgctgtgc gcatgccttc acccttccgc     3480

tcctccgcac tcatgggaat gtgtggcagt agaagcgctg ataacttgtc atgcccttct     3540

ccattgaatg taatggaacc agtcactgaa ctgatgcagg agcagtcata cctgaagtct     3600

gaattgggcc tgggacttgg agaaatggga tttgaaattc ctcctggaga aagctcagaa     3660

tctgtttttt cccaagcaac atcagaatca tcttctgtat gttctggtcc ctctcatgct     3720

aacagaagaa ctggagtacc ttctactgcc tcagtgggca aatccaaaac cccattagtg     3780

gcaaggaaga aagtgttccg agcatcggtg gctctaacgc caacagctcc ttctagaaca     3840

ggctctgtgc agacacctcc agatttggaa agttctgagg aagttgatgc agctgaagga     3900

gccccagaag ttgtaggacc taaatctgaa gtggaagaag ggcatggaaa actcccatca     3960

atgccagctg ctgaggaaat gcataaaaat gtggagcaag atgagttgca gcaagtcata     4020

cgggagatta aagagtctat tgttggggaa atcagacggg aaattgtaag tggacttttg     4080

gcagcagtat cttcaagtaa agcgtctaat tctaagcaag attatcatta aacagaaatt     4140

ataggttggc atggatccta ttagctgtgt aatactggaa ttatcaatga tatgcactgg     4200

tggaggtgtt atttgtgctt tagaagatac ttgctgttga gctgggctac tgtatacagt     4260

gtacaatgtg tatttcttca accatatatt ttaaaaagac gtacatagaa acttaggcac     4320

tttgctattt cttttctaaa ctatcaaaaa ctctagcagt ttgaaaagcc taatatttat     4380

ttgtatgtca gtatttttca tttgattccc tattagaatt aattttaaaa cttgaagact     4440

tccagactta tccaacttat aaataacata tttcttcaga ctaacatctt aaaacactga     4500

cctctatgag gtatttactg tgcaataact gattcatttt tttcagagct tgaagcatcc     4560

aatgattttt ccctccactg ctgttaatta atgtcacttc caagaagaaa aactgttctg     4620

ttgtaaaaaa tataattgct cttaattctt ggggaggtta ctaatagcag taggatagaa     4680

ttttatgagg ttacctacaa ctacttaatg tacttacact gtaagccttg ttgctttacc     4740

caagacaaat gtaattttat cattgcttat gtagtatttt tcttttggaa atgtgcctta     4800

tgttaaacac tatgtacttt tactttttgc attgtccaga cttctttatt agatggagat     4860

gtttcttttt ctgtcttcta gactaaatag agtatcatcc aaataatggg gcctatgact     4920

tgaatgaata gaaatgaata agctggtgtt tgttttttca aaatggaagt aatttagatt     4980

tgttctcctc atacataaaa tgattttagt tcagttttaa ccagtgaaaa ctttgttttt     5040

atgaaaaaaa aggaaaatgg tttcccattt ggttttatat gtgttaaata aatgtgtaaa     5100

gtaaccacca aatgttatta gaatttttct tctagcattt ataatttttt caactcctat     5160

tgtgtttctt tgtgtgtgat attttaatca aaagtggttg agttgttaac agtgttcttt     5220

gaaagaatct ctaaaaggct tataaatgtt tgaaatatca cacaaaggct gatttctaaa     5280

atatatatat attaaaacaa taaagtattt attttgccta aaaaaaaaaa aaaaaaaa       5338


<210>  1505
<211>  2978
<212>  DNA
<213>  homo sapiens

<400>  1505
ggcgggcgct cggcgactcg tccccggggc cccgcgcggg cccgggcagc aggggcgtga       60

tgtcacggca gggagggggc gcgggagccg ccgggccggc ggggaggcgg gggaggtgtt      120

ttccagcttt aaaaaggcag gaggcagagc gcggccctgc gtcagagcga gactcagagg      180

ctccgaactc gccggcggag tcgccgcgcc agatcccagc agcagggcgc gggcaccggg      240

gcgcgggcag ggctcggagc caccgcgcag gtcctagggc cgcggccggg ccccgccacg      300

cgcgcacacg cccctcgatg actttcctcc ggggcgcgcg gcgctgagcc cggggcgagg      360

gctgtcttcc cggagacccg accccggcag cgcggggcgg ccgcttctcc tgtgcctccg      420

cccgccgctc cactccccgc cgccgccgcg cggatgccaa gcaccagctt tccagtccct      480

tccaagtttc cacttggccc tgcggctgcg gtcttcggga gaggagaaac tttggggccc      540

gcgccgcgcg ccggcggcac catgaagtca gcggaggaag aacactatgg ctatgcatcc      600

tccaacgtca gccccgccct gccgctcccc acggcgcact ccaccctgcc ggccccgtgc      660

cacaaccttc agacctccac accgggcatc atcccgccgg cggatcaccc ctcggggtac      720

ggagcagctt tggacggtgg gcccgcgggc tacttcctct cctccggcca caccaggcct      780

gatggggccc ctgccctgga gagtcctcgc atcgagataa cctcgtgctt gggcctgtac      840

cacaacaata accagttttt ccacgatgtg gaggtggaag acgtcctccc tagctccaaa      900

cggtccccct ccacggccac gctgagtctg cccagcctgg aggcctacag agacccctcg      960

tgcctgagcc cggccagcag cctgtcctcc cggagctgca actcagaggc ctcctcctac     1020

gagtccaact actcgtaccc gtacgcgtcc ccccagacgt cgccatggca gtctccctgc     1080

gtgtctccca agaccacgga ccccgaggag ggctttcccc gcgggctggg ggcctgcaca     1140

ctgctgggtt ccccgcggca ctccccctcc acctcgcccc gcgccagcgt cactgaggag     1200

agctggctgg gtgcccgctc ctccagaccc gcgtcccctt gcaacaagag gaagtacagc     1260

ctcaacggcc ggcagccgcc ctactcaccc caccactcgc ccacgccgtc cccgcacggc     1320

tccccgcggg tcagcgtgac cgacgactcg tggttgggca acaccaccca gtacaccagc     1380

tcggccatcg tggccgccat caacgcgctg accaccgaca gcagcctgga cctgggagat     1440

ggcgtccctg tcaagtcccg caagaccacc ctggagcagc cgccctcagt ggcgctcaag     1500

gtggagcccg tcggggagga cctgggcagc cccccgcccc cggccgactt cgcgcccgaa     1560

gactactcct ctttccagca catcaggaag ggcggcttct gcgaccagta cctggcggtg     1620

ccgcagcacc cctaccagtg ggcgaagccc aagcccctgt cccctacgtc ctacatgagc     1680

ccgaccctgc ccgccctgga ctggcagctg ccgtcccact caggcccgta tgagcttcgg     1740

attgaggtgc agcccaagtc ccaccaccga gcccactacg agacggaggg cagccggggg     1800

gccgtgaagg cgtcggccgg aggacacccc atcgtgcagc tgcatggcta cttggagaat     1860

gagccgctga tgctgcagct tttcattggg acggcggacg accgcctgct gcgcccgcac     1920

gccttctacc aggtgcaccg catcacaggg aagaccgtgt ccaccaccag ccacgaggcc     1980

atcctctcca acaccaaagt cctggagatc ccactcctgc cggagaacag catgcgagcc     2040

gtcattgact gtgccggaat cctgaaactc agaaactccg acattgaact tcggaaagga     2100

gagacggaca tcgggaggaa gaacacacgg gtacggctgg tgttccgcgt tcacgtcccg     2160

caacccagcg gccgcacgct gtccctgcag gtggcctcca accccatcga atgctcccag     2220

cgctcagctc aggagctgcc tctggtggag aagcagagca cggacagcta tccggtcgtg     2280

ggcgggaaga agatggtcct gtctggccac aacttcctgc aggactccaa ggtcattttc     2340

gtggagaaag ccccagatgg ccaccatgtc tgggagatgg aagcgaaaac tgaccgggac     2400

ctgtgcaagc cgaattctct ggtggttgag atcccgccat ttcggaatca gaggataacc     2460

agccccgttc acgtcagttt ctacgtctgc aacgggaaga gaaagcgaag ccagtaccag     2520

cgtttcacct accttcccgc caacggtaac gccatctttc taaccgtaag ccgtgaacat     2580

gagcgcgtgg ggtgcttttt ctaaagacgc agaaacgacg tcgccgtaaa gcagcgtggc     2640

gtgttgcaca tttaactgtg tgatgtcccg ttagtgagac cgagccatcg atgccctgaa     2700

aaggaaagga aaagggaagc ttcggatgca ttttccttga tccctgttgg gggtgggggg     2760

cgggggttgc atactcagat agtcacggtt attttgcttc ttgcgaatgt ataacagcca     2820

aggggaaaac atggctcttc tgctccaaaa aactgagggg gtcctggtgt gcatttgcac     2880

cctaaagctg cttacggtga aaaggcaaat aggtatagct attttgcagg cacctttagg     2940

aataaacttt gcttttaagc ctgtaaaaaa aaaaaaaa                             2978


<210>  1506
<211>  4891
<212>  DNA
<213>  homo sapiens

<400>  1506
tttccgagtg cggtagcagg agggggcggg gaggtaagcg gaggctccga gctctaggcc       60

ggccggcggt ggcggcggcg aggccgggac tcgggcttag ggcctgctgt ggaggcagcg      120

gcggacgccg agctaagcag tttctctgga aacccccctg gtaagtgtgg aggaggcggg      180

acactctgac ccaagacgaa aggcctgtag ctccagccaa agaaaataaa ccttaggagg      240

gagaaggaaa aaaaaaatcc atcagctgtt cctgagaaca gcctgcattg gaatctacag      300

agaggacaac taatgtgagt gaggaagtga ctgtatgtgg actgtggaga aagtaagtca      360

cgtgggccct tgaggacctg gactgggtta ggaacagttg tactttcaga ggtgaggtgt      420

cgagaaggga aagtgaatgt ggtctggagt gtgtccttgg ccttggctcc acagggtgtg      480

ctttcctctg gggccgtcag ggagctcatc ccttgtgttc tgccagggtg gggtacgggg      540

tttgacactg aggagggtaa cctgctggct ggagcggcag agcagtggcc ttgatttgtc      600

ttttggaaga ttttaaaaac caaaaagcat aaacattctg gtccttcagc aatgctttct      660

ctgaagaaat acttaacgga aggacttctc cagttcacca ttctgctgag tttgattggg      720

gtacgggtgg acgtggatac ttacctgacc tcacagcttc ccccactccg ggagatcatc      780

ctggggccca gttctgccta tactcagacc cagttccaca acctgaggaa taccttggat      840

ggctatggta tccaccccaa gagcatagac ctggacaatt acttcactgc ccggcggctc      900

ctcagtcagg tgagggccct ggacaggttc caggtgccaa ccactgaggt aaatgcctgg      960

ctggttcacc gagacccaga ggggtctgtc tctggcagtc agcccaactc aggcctcgcc     1020

ctcgagagtt ccagtggcct ccaagatgtg acaggcccag acaacggggt gcgagaaagc     1080

gaaacggagc agggattcgg tgaagatttg gaggatttgg gggctgtagc ccccccagtc     1140

agtggagact taaccaaaga ggacatagat ctgattgaca tcctttggcg acaggatatt     1200

gatctggggg ctgggcgtga ggtttttgac tatagtcacc gccagaagga gcaggatgtg     1260

gagaaggagc tgcgagatgg aggcgagcag gacacctggg caggcgaggg cgcggaagct     1320

ctggcacgga acctgctagt ggatggagag actggggaga gcttccctgc acaggtgcct     1380

agtggggagg accagacggc cctgtccctg gaagagtgcc ttaggctgct ggaagccacc     1440

tgcccctttg gggagaatgc tgagtttcca gcagacattt ccagcataac agaagcagtg     1500

cctagtgaga gtgagccccc tgctcttcaa aacaacctct tgtctcctct tctgaccggg     1560

acagagtcac catttgattt ggaacagcag tggcaagatc tcatgtccat catggaaatg     1620

caggccatgg aagtgaacac atcagcaagt gaaatcctgt acagtgcccc tcctggagac     1680

ccactgagca ccaactacag ccttgccccc aacactccca tcaatcagaa tgtcagcctg     1740

catcaggcgt ccctgggggg ctgcagccag gacttcttac tcttcagccc cgaggtggaa     1800

agcctgcctg tggccagtag ctccacgctg ctcccgttgg cccccagcaa ttctaccagc     1860

ctcaactcca ccttcggctc caccaacctg acagggctct tctttccacc ccagctcaat     1920

ggcacagcca atgacacagc aggcccagag ctgcctgacc ctttgggggg tctgttagat     1980

gaagctatgt tggatgagat cagccttatg gacctggcca ttgaagaagg ctttaaccct     2040

gtgcaggcct cccagctgga ggaggaattt gactctgact caggcctttc cttagactcg     2100

agccatagcc cttcttccct aagcagctct gaaggcagtt cttcctcttc ttcctcctcc     2160

tcttcctctt cttcctctgc ttcttcctct gcctcttcct ccttttctga ggaaggtgcg     2220

gttggctaca gctctgactc tgagaccctg gatctggaag aggccgaggg tgctgtgggc     2280

taccagcctg agtattccaa gttctgccgc atgagctacc aggatccagc tcagctctca     2340

tgcctgccct acctggagca cgtgggccac aaccacacat acaacatggc acccagtgcc     2400

ctggactcag ccgacctgcc accacccagt gccctcaaga aaggcagcaa ggagaagcag     2460

gctgacttcc tggacaagca gatgagccgg gatgagcacc gagcccgagc catgaagatc     2520

cctttcacca atgacaaaat catcaacctg cctgtggagg agttcaatga actgctgtcc     2580

aaataccagt tgagtgaagc ccagctgagc ctcatccgag acatccggcg ccggggcaag     2640

aacaagatgg cggcgcagaa ctgccgcaag cgcaagctgg acaccatcct gaatctggag     2700

cgtgatgtgg aggacctgca gcgtgacaaa gcccggctgc tgcgggagaa agtggagttc     2760

ctgcgctccc tgcgacagat gaagcagaag gtccagagcc tgtaccagga ggtgtttggg     2820

cggctgcgag atgagaacgg acgaccctac tcgcccagtc agtatgcgct ccagtacgcc     2880

ggggacggca gtgtcctcct catcccccgc acgatggccg accagcaggc ccggcggcag     2940

gagaggaagc caaaggaccg gagaaagtga gcctggggaa gaagggggtt tgaagcccac     3000

caagaccgaa actggagaag ggctggacct ggacctggac ctggacctac agcggggact     3060

taaatgcctt cttatccaat atatcttctc agatgggatg actgcgggtc agtgtacagg     3120

aagaggcagg cactggctgg ctcagctcca ctcgggtgga gtggaagtgg ccagaccatt     3180

tagacggaca gggtcctcac cctacccctt tcctgtgagg caggggtggt ggtggagttg     3240

ctggaggtag aggagctatg tggagcaaag gccgacagag gggaaggaat ggacctgtga     3300

gaggaaggga aggtggcaga aagtctcatt tcaggaagga gggatagaag gaaggaagga     3360

aggaaccccc ccccccccga aaaaaaaatc aaagcgggaa gaaaatcaga gggaaggtta     3420

aggttggctc tggccaggat tccaggcagc aggttggagt gactggtggg cctagatcac     3480

tggtgtgata aaccccaatt ttcaccccgg ggggggtggg gtacacagac acagggtggg     3540

ggtggggagg gacggtgtta actctttctg ctccttgcat tttgacatcc ctgaagggga     3600

gctcttggat atcattggcc atgtttcaat cgaatggagc cactgggccc caacactggc     3660

tttgagattt agagtcaaag ggtagagtga acaggaaagg gtcacgtggt cccatgttgc     3720

aacagcccca acatcacgca tgtcattcac tgccttgcca ctccatctcc ctccgtgctc     3780

cagccacccc tgagctgagg ctcccattgt ctccatcaga gcctgcatgt gtatgccgtc     3840

ctcccctggt ccggtgtttg tgttccccac ccctcacaga ctgcctgagc tcttctgtaa     3900

gctggggtag ggtgatggca gtgctccggg aactgggcct gcagccttcc tcttctggga     3960

ctgctgtgag gcagaggaat gatggagaat ctagtgtagc agcctccagg caggattcag     4020

cacaacactg gggagtcacc cttccctcgg gcctctgcct accaacaact gggcttatca     4080

ctgggaaaac acaaaaaatt acacaaccca gcaacaacaa aagaactagt cctcttagaa     4140

tttcttgcgc tttgattttt ttagggcttg tgccctgttt cacttatagg gtctagaatg     4200

cttgtgttga gtaaaaagga gatgcccaat attcaaagct gctaaatgtt ctctttgcca     4260

taaagactcc gtgtaactgt gtgaacactt gggatttttc tcctctgtcc cgaggtcgtc     4320

gtctgctttc ttttttgggt ttctttctag aagattgaga agtgcatatg acaggctgag     4380

agcacctccc caaacacaca agctctcagc cacaggcagc ttctccacag ccccagcttc     4440

gcacaggctc ctggagggct gcctggggga ggcagacatg ggagtgccaa ggtggccaga     4500

tggttccagg actacaatgt ctttattttt aactgtttgc cactgctgcc ctcacccctg     4560

cccggctctg gagtaccgtc tgccccagac aagtgggagt gaaatggggg tggggggaag     4620

cactgattcc cagttagggg gtgcctaact gagcagtagg gatagaaggt gtgaacctgg     4680

gagtgctttt ataaattatt ttccttgtag attttatttt taatttatct ctgtgacctg     4740

ccagggagag gggagagaga gagagatgct gttgagcaca tgacaaaata aaataaaatg     4800

gatgattcat tcttaagtgc actttttccc cactttgaat ttaaattgag aataaaggaa     4860

atggactcat tgtaaaaaaa aaaaaaaaaa a                                    4891


<210>  1507
<211>  9495
<212>  DNA
<213>  homo sapiens

<400>  1507
ggccgcggag gctcgggacc cggctggccg cgcggcgccg cagccgcccc ctcccccaca       60

ccccctcccc cccgcggcgg cggcgcgagc gggcggcggc tgtgcggtgc ggtgcagagc      120

ggaggcggag gcgggcgcgc gggcagctcg cgggcacccg gccgggccgg cgcgggagcg      180

ggaaagggtg cgctatgcct ttaacacccg cgtacagtag gcatgtatag tggagtgtag      240

ggaaactcta ggcggggtta aagttcagct catggagcgg caatagcgct ggctggctgg      300

ctgcagttga gccgacttgg aaatgtgaac gcaagaagca ggcttgattt ttttttctcc      360

ccccttctct ctctctctct ctctctctct tcctctctcc ctctttctcc tctctcaccc      420

acactcacgc acacctccaa accgcacacc cagacgcaca cgcatacccc agcgcccggc      480

agttatgtat tctccgctct gtctcaccca ggatgaattt catcctttca tcgaagcact      540

tctgccccac gtccgagcct ttgcctacac atggttcaac ctgcaggccc gaaaacgaaa      600

atacttcaaa aaacatgaaa agcgtatgtc aaaagaagaa gagagagccg tgaaggatga      660

attgctaagt gaaaaaccag aggtcaagca gaagtgggca tctcgacttc tggcaaagtt      720

gcggaaagat atccgacccg aatatcgaga ggattttgtt cttacagtta cagggaaaaa      780

acctccatgt tgtgttcttt ccaacccaga ccagaaaggc aagatgcgaa gaattgactg      840

cctccgccag gcagataaag tctggaggtt ggaccttgtt atggtgattt tgtttaaagg      900

tattccgctg gaaagtactg atggcgagcg ccttgtaaag tccccacaat gctctaatcc      960

agggctctgt gtccaacccc atcacatagg ggtttctgtt aaggaactcg atttatattt     1020

ggcatacttt gtgcatgcag cagattcaag tcaatctgaa agtcccagcc agccaagtga     1080

cgctgacatt aaggaccagc cagaaaatgg acatttgggc ttccaggaca gttttgtcac     1140

atcaggtgtt tttagtgtca ctgagctagt aagagtgtca cagacaccaa tagctgcagg     1200

aactggccca aatttttctc tctcagattt ggaaagttct tcatactaca gcatgagtcc     1260

aggagcaatg aggaggtctt tacccagcac atcctctacg agctccacaa agcgcctcaa     1320

gtctgtggag gatgaaatgg acagtcctgg tgaggagcca ttttatacag gccaagggcg     1380

ctccccagga agtggcagtc agtcaagtgg atggcatgaa gtggagccag gaatgccatc     1440

tccaaccaca ctgaagaagt cggagaagtc tggtttcagc agcccctccc cttcacagac     1500

ctcctccctg ggaacggcgt tcacacagca tcaccgacct gtcattacag gacccagagc     1560

aagtccgcat gcaacaccat cgactcttca tttcccgaca tcacccatta tccagcagcc     1620

tgggccttac ttctcacacc cagccatccg ctatcaccct caggagacgc tgaaagaatt     1680

tgtccaactt gtctgccctg atgctggtca gcaggctgga caggtggggt tcctcaatcc     1740

caatgggagc agccaaggca aggtgcacaa cccattcctt cccaccccaa tgttgccacc     1800

gccaccgcca ccaccgatgg ccaggcctgt gcctctgccg gtgccagaca caaagcctcc     1860

aaccacgtca acagaaggag gtgcagcctc ccccacgtca ccaacctact cgacacccag     1920

cacctccccc gcaaaccgat tcgtcagtgt tggaccacgg gatccaagct ttgtaaatat     1980

ccctcaacag acacagtcct ggtacctggg ataaaagttg cagcgtccca ccatccacca     2040

gacagaccac ctgacccctt ctcaactctg taacatggac gcaacctcaa cccagcgcag     2100

ttacaacttc actatcagcg gaaggggaga aaaaccgatt caaatcaact tgtacatgga     2160

aacagcaagc attatggtca aacagcaaag gccataacct tttgggattt tttttttttt     2220

aaaatacttt agggactgtt gtaatttctc atatggtgct ggaaatggtt gggctttgta     2280

acatttgaag tgtttccatg gtagcgtgag cattaggtga cgtggctagc ggaggactac     2340

ccttgctcac tgacttcctg ttgtaacaca ctttccttac ggagcctggc tgtttcacag     2400

tatttcatga atttacccac acaggtgtga tcctccttga gcattgagga ggcacatgga     2460

gaactaaatc ttttgtagta gctgagatct gcaatatata acgggacagt caaagggcaa     2520

tgtttttctg taacatattg gaaaaagaaa atgcagttat attccttttt tatttgttcc     2580

tttagtttgt tttggttcag cagtcagcag ttaagtatat aacatggccc gcaaggacaa     2640

tgaatccact cacattgcag aacaattccg aaaatggcaa actactacta ctactgttca     2700

gttttttaaa agttttgaaa tgctgcactt acatttaaaa aaacaacaac aacatttttt     2760

caacaatttc aacaatgaca caaaaattca catggaaatg gggaagatgg tctgttttga     2820

cagaaactga caggaatcaa tcaaaacaat cgaattttga attgagtaaa gtgcaatttc     2880

attggatagc taaatatctt tgtaagatag agattgttga aaattctatt tttgtttttc     2940

tagtcctttc accccaggac tctaaattat tggggtaaaa aacagccttg caagaaaaag     3000

gggagctatt tttgcttttt atgtttttta ttgttaaact tgtatccctt taaaaactga     3060

aggaaattaa aaaaaaaaaa caaaaaaaca aatctaatgg tgcttttacc acaatatgtt     3120

aactacatta aatgctaatt aattattttc tgttatcaaa gcacatgact aaaatgaaat     3180

catggtatct gttaatttta taagctagaa gtcactataa tggattacgc caattctaaa     3240

aaattttaca cctatctggc atcataggat ttatcagtta tcagacacct cattgtacca     3300

gagattgtcc agaagtttta aagacctttg catccctgaa ctgggctatg ggaaataata     3360

atagtaataa taataataat aataatgatg aaaccaatac tgacacaaat gctggtgccc     3420

attcagatca agggtacttg ttagggaaaa aaaaaaaagt ttgcaccccc aaacgtcctg     3480

tatcttatga aaaaaaaaac aaaaaacaaa aacaaaaaaa aaacacaaaa aaccacagaa     3540

acaaaaacaa aaaaaagtgc aagtgatttt tctaccagac agcgaagcac ccctttgctt     3600

cccatgcgac ttcaagaagg tttcctatac tatacatata tatacgttct ggttggcaag     3660

ccctgctgat cagagaaagt ctctgcatgt tctagtgtta gtaactaatt tttatatagt     3720

taatgtagga taaagtagag tgcattaaga cacaatattg taatccctac tctaggcact     3780

tgcctttaaa ctatgttttt cagcccttca gaagggttct actactgtcc tatacaatca     3840

agtaactgaa attcttggga agacactttg ctcctcatct ttctccccga aacaatgttg     3900

ttttgttttg ttttttttcc ttaatttgca cgaaaacaaa aattccatat caatgtgcct     3960

tgccctggat agcgattatt tgtggaattg ttgcacatgc tcctctattg aaaggggttt     4020

ttccctagtc aagcatttgg agacactttt tgtaaatgtg acttttatgt cagccatcgt     4080

cagtttcaac atctagaact aaatagaaag ctagttgttc cgcagatagg agtagtcttt     4140

attgtcctgt acggtcggtg gcagtgctat tctgagatct gtagatgctt agaatatcag     4200

tattttggat gttgctgcat tttacaattt atttggagtc ttcctttatt ttcccccaga     4260

tatatgaaaa tatgcaatac ctgcttatat catgtagaaa agcttagcaa ttattaattt     4320

ttcttttatt tttttttatt tgaccaaagt cggtgctgca cttgacgcag tgtgttttag     4380

gtgtttgtct ttgtactttt ttgtgatttt tgaatgcacg tgcgcaggaa gggctcctct     4440

tagagaagca gtcaaactgt gaagcactaa gctgaccctg cttcaagcaa ttttgttttt     4500

acaactgttc ctttcacaag caagccttaa aaaaaaaaaa gacaacttcc tttttcttca     4560

gctcccacac cccatttttc ttagcagact gcagtcaatc cacattcaat aaaaagtata     4620

taatgcccat ttttatatgc acgtttttaa acttccaagt tctgaaaatt gtttactggt     4680

tatctctatt taaggaaaaa aaaataaaat aaaacatttt ggattttcat atgtgtctga     4740

taagtggttg aatagtcgtt tggcgctgtt gtatggtgtg attgtcagtg tatggtgtca     4800

cttcctatag ccagccagca tactttgcct tcccctatag cacttagctg ggcattactt     4860

tattatgaca tatgtgcact aaaaaatgaa aaaaaggaaa aaaagaaaaa aaaaaagaaa     4920

aaatagcagc tttcagtgct tcacagtgaa gggaaaaaag cctagacaaa cattttgtca     4980

gaaccttgca ataagccaag gtattaccag taaattggtt gtatatacaa taaaattgca     5040

ccctttttta aacaaaacaa actaagcaat agtttgggca gttttagttg tttttagtga     5100

gcatgttgta gtcatgactg caaagagaga gaataaactg cccgctcaga agatatgtaa     5160

tttgtattgt tgtatagttt tattgattac actgatttat tctaccctat tttataatgc     5220

aggacttttg taatgttgtt taaatgagga aaaatttctg tcaaattagc ctagtaaaat     5280

ttctgatcgt tcattataaa ggcagcgttc atagaattgc ttttctttct ttttaccccc     5340

cctttgggaa ctggatttaa gtttaaaact ttcctgtttc cttttttttt ttttttttgt     5400

aagtatttaa atacaattat ttttttctct caatggtata gcatattcct atgcttgaga     5460

agtataggtc tactgaaaaa ccattgtaaa tggacgttac aggtatgctg tatttttgaa     5520

ggtattttgt tgtattaagt ttgatgaagc taaaattagg gaactctgaa cagatttgca     5580

ggaaaaaatg ttttaaaggc tttaaaacat tagggaggca gtctagggtg ataacgaaca     5640

ggggttaagt attaaataca cgaagttaca tttttgttca tgtttcattg tccagaaagc     5700

agcaggaaac tattcagttg tgatcaagca ggaaaaaaga aacaccaaca gttgccagtg     5760

tttttgcttt ttagcttaaa agcatagtga agatgcttga ggaagacttt gctacctggg     5820

gtgtgtagac agacagactg agagctatca gcatttgaag gcccagccct tgactctgag     5880

acacatttga attttttctt tcccatcaaa tggcattaac aagattgggc aaagatgagt     5940

ccctcaaatt tctgtgtttt ttgtttgttt gtttgtttgt tttttctttg ggaactgaag     6000

tcagaggcac gaacactaac tcttagcatt tttctgtaga ctttttcttc tggcccttgt     6060

ccctgccagc aaaacgcccc ttttctgatc attcgtgcgc agagggcctc ccagtaatgc     6120

cacgctctcc atgctagaga gccttctctt tcctctgagg tttgaactga tgttctgtgt     6180

cttcacaccc tggcatgaca gttacgtgtg gtcagcccgc tccccaggcc cgtccctgcc     6240

gccgccaggt gtgggctcta ggcaggccga caaggttaca cctcccagag cttgtgatct     6300

tcattttctg acagtcaaag tgtgaaggaa cccagacttc cccgagccac ggtgttcagt     6360

cagcccacag gaatatgcaa gacccatctc caaaagtttg tctttgattt tttccaagcc     6420

cttagcccca taagctttga atcctgtagt tacagtggca taaaggactg acaaaacctg     6480

gataaggaaa aacctttttt ttctatgaat tttttttgtt ttttagggga aagggattct     6540

aagaatgtca tttaatgtac tttgcatcat gtctctagaa atatctttgt ccatagtggt     6600

ggtggagtct ctctctctct ctctcttttt gtttgcttct gttttctttc ttgtcttcat     6660

tctttctttt cttttttatt tctggtagca ggcctccata gaacaaatct aaaacacaac     6720

caccatagta atgtaaggag agcttcagtg gcacctcaaa acccaccctt cgagatctgt     6780

ccaaagacag tctcagaaag ctgcactgcc caccggctca gctttcattc aaaaaggctt     6840

ccaaggccaa ttctgtcttg aagtcaatgc atgtatttac tgtttgacag taaacccgct     6900

ctgccttctc cacgtccaag gctgtgcatt cgtctaatta gcgtcgtgta tgttttcctt     6960

ttattttttc caataaaaaa gcagtgggat gaaaattgct ttgatatata gcaggtaaca     7020

ttgaagctat tccatagcac ttaactgtag tgaatactgt gtcaccaatt ttgaaatcaa     7080

tttaatgttt aatgcaaatc cattacatgg tgctattata ggctgacaaa atgatttaca     7140

caaatgtgac aacttgggct caattcactc tgctttccaa cagtgtaaat gcatagcagt     7200

gtttatctgc atgagaacta tgcactaatc tatctgaaga aaaaaactat atcaactttg     7260

gtatctactt tccgtttact tcaatccttg cctttttggt cattgttata atgccagctt     7320

taggacagaa agaattataa gaaaaccagc ataatacctg atatattaaa atgtagtgcc     7380

tgtgaaatct gtattatatt gctcttctga agtaagattt ttctacaccg gtagccttcg     7440

ctgtctgtca gtcaggacct tctggtatag gtgatgtaaa ataaccgtac aatattaatg     7500

catgcgattc cataatgctt agtgaactgt atgaatatta ctcaaagtta tgttagtctt     7560

tttttccgac ttggttcttg tcagctaggt ttaaaggtat ttcactgaga acgcaaattc     7620

tgtcttttct tgatttcggc tgttttcagt attttggagg tatacattta cttaaattca     7680

gtattactcg tgttttgttt ttgtttttgt tttttgtttt ctttttccta ggggacaagc     7740

atgggtgttt gatttcagaa atcagtacct ggcgagattt ttgtctcaaa acgactattt     7800

gaatttcaag aactgtgctg cgaagacact ctgagaacat ttgcaagtca ggggcatttt     7860

ccttgaccct tgactgatgc tatgcggaga ctgatacatt ttcttaatgg acaatgttca     7920

agccaggtac ccatgcttga tctgtcttca caccagacct cctcatatta aaaggaaaaa     7980

taagaaaaaa aatgtaagaa atcacatggc tatttagttt catgcacagt tgcaatattt     8040

tcttcaaaaa taaaactctg tacaaacttt gggcccgatt cataagaaaa agaagtttgc     8100

tattaacacg ggattttttt aatatacttt ttttggtcta aatttgaaat tacttgcttc     8160

ccaaattaaa taaatttcat ctcatttttt tccctaaacc agcacccatc tgccttttat     8220

tccccaaaga gttacctttc ccagattagg gggatggtat gtggggagca gatagcggaa     8280

atgcttagaa agataagggg gaccacccac agctggtcgt gagaacaggg agacagtgtg     8340

tgggggtggg acctcatctg tgtgcctggt atcctgagtt ttacatgtag atgcattcgc     8400

ctatttgatt cagaaaaata aactttccca aaatgtgtct gaaccacaag agcatacagt     8460

ggaagtgcta cctctaatct aaccagagca ccttcatggt ggaagacacc caccaggtca     8520

tacaatgtga acttttgtat ctctgcagtg gtttcaagga caaatagtgt ccaatgtatt     8580

gggccatttt tcctgctgtt tttatactca acttctcaaa atgaaaaaag cttttatttt     8640

tcctttgact tatttgtgtt gttcttattt tttaaatttt tattttttga taatagtctg     8700

taagttagcc tttttgggtt tttttttttt ttttttggct tttttttttg tttgtttttt     8760

tttcttttga cattgcaacc gaaggtcata aggccgctag ctccgctggg acagaggctt     8820

gagagaacta acggctcggt gccttctccc tggtctcaga ccatcgtctc tgcactgcga     8880

aggcatttgg tagcctcgcc actgagatac taactagacc tagactagga gctttatcag     8940

gttctaggag gtcctttagg aagactctca aaggcaaatc cctgatcccc cgccccaccc     9000

ttagccctgc cctctcacca gagcaaaatt cactggggac ttttcccacc acacatggaa     9060

atctgtccac tcggaatacc tctgttttcc atttcaaatt gtagggggag gggatggaac     9120

acttccagtg atggtaagag atctgttatg aaacgaaaca ccccccgtgt taataacttg     9180

gtctgaaatc tgtttttatg agccgggccc cctgtgcctc tagtatactt gtattgactc     9240

tcatagttac ccttttagtt ttactgtgtt ctgtgaaaat ttgtaattgg ttgagaatca     9300

ctgtgggcgt ccattcttat tcaactaaat ctccacaggt tttttgagct ggtgtggatt     9360

agtttaactc ttgtattcaa ccattagtgc taccaccttc tcacattaca atacaattac     9420

tggaagcaag tactgcattt cctatgcaac aaaaaaggaa aaataaaaaa ttgctaatgc     9480

taaaaaaaaa aaaaa                                                      9495


<210>  1508
<211>  9403
<212>  DNA
<213>  homo sapiens

<400>  1508
ggccgcggag gctcgggacc cggctggccg cgcggcgccg cagccgcccc ctcccccaca       60

ccccctcccc cccgcggcgg cggcgcgagc gggcggcggc tgtgcggtgc ggtgcagagc      120

ggaggcggag gcgggcgcgc gggcagctcg cgggcacccg gccgggccgg cgcgggagcg      180

ggaaagggtg cgctatgcct ttaacacccg cgtacagtag gcatgtatag tggagtgtag      240

ggaaactcta ggcggggtta aagttcagct catggagcgg caatagcgct ggctggctgg      300

ctgcagttga gccgacttgg aaatgtgaac gcaagaagca ggcttgattt ttttttctcc      360

ccccttctct ctctctctct ctctctctct tcctctctcc ctctttctcc tctctcaccc      420

acactcacgc acacctccaa accgcacacc cagacgcaca cgcatacccc agcgcccggc      480

agttatgtat tctccgctct gtctcaccca ggatgaattt catcctttca tcgaagcact      540

tctgccccac gtccgagcct ttgcctacac atggttcaac ctgcaggccc gaaaacgaaa      600

atacttcaaa aaacatgaaa agcgtatgtc aaaagaagaa gagagagccg tgaaggatga      660

attgctaagt gaaaaaccag aggtcaagca gaagtgggca tctcgacttc tggcaaagtt      720

gcggaaagat atccgacccg aatatcgaga ggattttgtt cttacagtta cagggaaaaa      780

acctccatgt tgtgttcttt ccaacccaga ccagaaaggc aagatgcgaa gaattgactg      840

cctccgccag gcagataaag tctggaggtt ggaccttgtt atggtgattt tgtttaaagg      900

tattccgctg gaaagtactg atggcgagcg ccttgtaaag tccccacaat gctctaatcc      960

agggctctgt gtccaacccc atcacatagg ggtttctgtt aaggaactcg atttatattt     1020

ggcatacttt gtgcatgcag cagattcaag tcaatctgaa agtcccagcc agccaagtga     1080

cgctgacatt aaggaccagc cagaaaatgg acatttgggc ttccaggaca gttttgtcac     1140

atcaggtgtt tttagtgtca ctgagctagt aagagtgtca cagacaccaa tagctgcagg     1200

aactggccca aatttttctc tctcagattt ggaaagttct tcatactaca gcatgagtcc     1260

aggagcaatg aggaggtctt tacccagcac atcctctacg agctccacaa agcgcctcaa     1320

gtctgtggag gatgaaatgg acagtcctgg tgaggagcca ttttatacag gccaagggcg     1380

ctccccagga agtggcagtc agtcaagtgg atggcatgaa gtggagccag gaatgccatc     1440

tccaaccaca ctgaagaagt cggagaagtc tggtttcagc agcccctccc cttcacagac     1500

ctcctccctg ggaacggcgt tcacacagca tcaccgacct gtcattacag gacccagagc     1560

aagtccgcat gcaacaccat cgactcttca tttcccgaca tcacccatta tccagcagcc     1620

tgggccttac ttctcacacc cagccatccg ctatcaccct caggagacgc tgaaagaatt     1680

tgtccaactt gtctgccctg atgctggtca gcaggctgga caggtggggt tcctcaatcc     1740

caatgggagc agccaaggca aggtgcacaa cccattcctt cccaccccaa tgttgccacc     1800

gccaccgcca ccaccgatgg ccaggcctgt gcctctgccg gtgccagaca caaagcctcc     1860

aaccacgtca acagaaggag gtgcagcctc ccccacgtca ccaatcctgg tacctgggat     1920

aaaagttgca gcgtcccacc atccaccaga cagaccacct gaccccttct caactctgta     1980

acatggacgc aacctcaacc cagcgcagtt acaacttcac tatcagcgga aggggagaaa     2040

aaccgattca aatcaacttg tacatggaaa cagcaagcat tatggtcaaa cagcaaaggc     2100

cataaccttt tgggattttt ttttttttaa aatactttag ggactgttgt aatttctcat     2160

atggtgctgg aaatggttgg gctttgtaac atttgaagtg tttccatggt agcgtgagca     2220

ttaggtgacg tggctagcgg aggactaccc ttgctcactg acttcctgtt gtaacacact     2280

ttccttacgg agcctggctg tttcacagta tttcatgaat ttacccacac aggtgtgatc     2340

ctccttgagc attgaggagg cacatggaga actaaatctt ttgtagtagc tgagatctgc     2400

aatatataac gggacagtca aagggcaatg tttttctgta acatattgga aaaagaaaat     2460

gcagttatat tcctttttta tttgttcctt tagtttgttt tggttcagca gtcagcagtt     2520

aagtatataa catggcccgc aaggacaatg aatccactca cattgcagaa caattccgaa     2580

aatggcaaac tactactact actgttcagt tttttaaaag ttttgaaatg ctgcacttac     2640

atttaaaaaa acaacaacaa cattttttca acaatttcaa caatgacaca aaaattcaca     2700

tggaaatggg gaagatggtc tgttttgaca gaaactgaca ggaatcaatc aaaacaatcg     2760

aattttgaat tgagtaaagt gcaatttcat tggatagcta aatatctttg taagatagag     2820

attgttgaaa attctatttt tgtttttcta gtcctttcac cccaggactc taaattattg     2880

gggtaaaaaa cagccttgca agaaaaaggg gagctatttt tgctttttat gttttttatt     2940

gttaaacttg tatcccttta aaaactgaag gaaattaaaa aaaaaaaaca aaaaaacaaa     3000

tctaatggtg cttttaccac aatatgttaa ctacattaaa tgctaattaa ttattttctg     3060

ttatcaaagc acatgactaa aatgaaatca tggtatctgt taattttata agctagaagt     3120

cactataatg gattacgcca attctaaaaa attttacacc tatctggcat cataggattt     3180

atcagttatc agacacctca ttgtaccaga gattgtccag aagttttaaa gacctttgca     3240

tccctgaact gggctatggg aaataataat agtaataata ataataataa taatgatgaa     3300

accaatactg acacaaatgc tggtgcccat tcagatcaag ggtacttgtt agggaaaaaa     3360

aaaaaagttt gcacccccaa acgtcctgta tcttatgaaa aaaaaaacaa aaaacaaaaa     3420

caaaaaaaaa acacaaaaaa ccacagaaac aaaaacaaaa aaaagtgcaa gtgatttttc     3480

taccagacag cgaagcaccc ctttgcttcc catgcgactt caagaaggtt tcctatacta     3540

tacatatata tacgttctgg ttggcaagcc ctgctgatca gagaaagtct ctgcatgttc     3600

tagtgttagt aactaatttt tatatagtta atgtaggata aagtagagtg cattaagaca     3660

caatattgta atccctactc taggcacttg cctttaaact atgtttttca gcccttcaga     3720

agggttctac tactgtccta tacaatcaag taactgaaat tcttgggaag acactttgct     3780

cctcatcttt ctccccgaaa caatgttgtt ttgttttgtt ttttttcctt aatttgcacg     3840

aaaacaaaaa ttccatatca atgtgccttg ccctggatag cgattatttg tggaattgtt     3900

gcacatgctc ctctattgaa aggggttttt ccctagtcaa gcatttggag acactttttg     3960

taaatgtgac ttttatgtca gccatcgtca gtttcaacat ctagaactaa atagaaagct     4020

agttgttccg cagataggag tagtctttat tgtcctgtac ggtcggtggc agtgctattc     4080

tgagatctgt agatgcttag aatatcagta ttttggatgt tgctgcattt tacaatttat     4140

ttggagtctt cctttatttt cccccagata tatgaaaata tgcaatacct gcttatatca     4200

tgtagaaaag cttagcaatt attaattttt cttttatttt tttttatttg accaaagtcg     4260

gtgctgcact tgacgcagtg tgttttaggt gtttgtcttt gtactttttt gtgatttttg     4320

aatgcacgtg cgcaggaagg gctcctctta gagaagcagt caaactgtga agcactaagc     4380

tgaccctgct tcaagcaatt ttgtttttac aactgttcct ttcacaagca agccttaaaa     4440

aaaaaaaaga caacttcctt tttcttcagc tcccacaccc catttttctt agcagactgc     4500

agtcaatcca cattcaataa aaagtatata atgcccattt ttatatgcac gtttttaaac     4560

ttccaagttc tgaaaattgt ttactggtta tctctattta aggaaaaaaa aataaaataa     4620

aacattttgg attttcatat gtgtctgata agtggttgaa tagtcgtttg gcgctgttgt     4680

atggtgtgat tgtcagtgta tggtgtcact tcctatagcc agccagcata ctttgccttc     4740

ccctatagca cttagctggg cattacttta ttatgacata tgtgcactaa aaaatgaaaa     4800

aaaggaaaaa aagaaaaaaa aaaagaaaaa atagcagctt tcagtgcttc acagtgaagg     4860

gaaaaaagcc tagacaaaca ttttgtcaga accttgcaat aagccaaggt attaccagta     4920

aattggttgt atatacaata aaattgcacc cttttttaaa caaaacaaac taagcaatag     4980

tttgggcagt tttagttgtt tttagtgagc atgttgtagt catgactgca aagagagaga     5040

ataaactgcc cgctcagaag atatgtaatt tgtattgttg tatagtttta ttgattacac     5100

tgatttattc taccctattt tataatgcag gacttttgta atgttgttta aatgaggaaa     5160

aatttctgtc aaattagcct agtaaaattt ctgatcgttc attataaagg cagcgttcat     5220

agaattgctt ttctttcttt ttaccccccc tttgggaact ggatttaagt ttaaaacttt     5280

cctgtttcct tttttttttt ttttttgtaa gtatttaaat acaattattt ttttctctca     5340

atggtatagc atattcctat gcttgagaag tataggtcta ctgaaaaacc attgtaaatg     5400

gacgttacag gtatgctgta tttttgaagg tattttgttg tattaagttt gatgaagcta     5460

aaattaggga actctgaaca gatttgcagg aaaaaatgtt ttaaaggctt taaaacatta     5520

gggaggcagt ctagggtgat aacgaacagg ggttaagtat taaatacacg aagttacatt     5580

tttgttcatg tttcattgtc cagaaagcag caggaaacta ttcagttgtg atcaagcagg     5640

aaaaaagaaa caccaacagt tgccagtgtt tttgcttttt agcttaaaag catagtgaag     5700

atgcttgagg aagactttgc tacctggggt gtgtagacag acagactgag agctatcagc     5760

atttgaaggc ccagcccttg actctgagac acatttgaat tttttctttc ccatcaaatg     5820

gcattaacaa gattgggcaa agatgagtcc ctcaaatttc tgtgtttttt gtttgtttgt     5880

ttgtttgttt tttctttggg aactgaagtc agaggcacga acactaactc ttagcatttt     5940

tctgtagact ttttcttctg gcccttgtcc ctgccagcaa aacgcccctt ttctgatcat     6000

tcgtgcgcag agggcctccc agtaatgcca cgctctccat gctagagagc cttctctttc     6060

ctctgaggtt tgaactgatg ttctgtgtct tcacaccctg gcatgacagt tacgtgtggt     6120

cagcccgctc cccaggcccg tccctgccgc cgccaggtgt gggctctagg caggccgaca     6180

aggttacacc tcccagagct tgtgatcttc attttctgac agtcaaagtg tgaaggaacc     6240

cagacttccc cgagccacgg tgttcagtca gcccacagga atatgcaaga cccatctcca     6300

aaagtttgtc tttgattttt tccaagccct tagccccata agctttgaat cctgtagtta     6360

cagtggcata aaggactgac aaaacctgga taaggaaaaa cctttttttt ctatgaattt     6420

tttttgtttt ttaggggaaa gggattctaa gaatgtcatt taatgtactt tgcatcatgt     6480

ctctagaaat atctttgtcc atagtggtgg tggagtctct ctctctctct ctctttttgt     6540

ttgcttctgt tttctttctt gtcttcattc tttcttttct tttttatttc tggtagcagg     6600

cctccataga acaaatctaa aacacaacca ccatagtaat gtaaggagag cttcagtggc     6660

acctcaaaac ccacccttcg agatctgtcc aaagacagtc tcagaaagct gcactgccca     6720

ccggctcagc tttcattcaa aaaggcttcc aaggccaatt ctgtcttgaa gtcaatgcat     6780

gtatttactg tttgacagta aacccgctct gccttctcca cgtccaaggc tgtgcattcg     6840

tctaattagc gtcgtgtatg ttttcctttt attttttcca ataaaaaagc agtgggatga     6900

aaattgcttt gatatatagc aggtaacatt gaagctattc catagcactt aactgtagtg     6960

aatactgtgt caccaatttt gaaatcaatt taatgtttaa tgcaaatcca ttacatggtg     7020

ctattatagg ctgacaaaat gatttacaca aatgtgacaa cttgggctca attcactctg     7080

ctttccaaca gtgtaaatgc atagcagtgt ttatctgcat gagaactatg cactaatcta     7140

tctgaagaaa aaaactatat caactttggt atctactttc cgtttacttc aatccttgcc     7200

tttttggtca ttgttataat gccagcttta ggacagaaag aattataaga aaaccagcat     7260

aatacctgat atattaaaat gtagtgcctg tgaaatctgt attatattgc tcttctgaag     7320

taagattttt ctacaccggt agccttcgct gtctgtcagt caggaccttc tggtataggt     7380

gatgtaaaat aaccgtacaa tattaatgca tgcgattcca taatgcttag tgaactgtat     7440

gaatattact caaagttatg ttagtctttt tttccgactt ggttcttgtc agctaggttt     7500

aaaggtattt cactgagaac gcaaattctg tcttttcttg atttcggctg ttttcagtat     7560

tttggaggta tacatttact taaattcagt attactcgtg ttttgttttt gtttttgttt     7620

tttgttttct ttttcctagg ggacaagcat gggtgtttga tttcagaaat cagtacctgg     7680

cgagattttt gtctcaaaac gactatttga atttcaagaa ctgtgctgcg aagacactct     7740

gagaacattt gcaagtcagg ggcattttcc ttgacccttg actgatgcta tgcggagact     7800

gatacatttt cttaatggac aatgttcaag ccaggtaccc atgcttgatc tgtcttcaca     7860

ccagacctcc tcatattaaa aggaaaaata agaaaaaaaa tgtaagaaat cacatggcta     7920

tttagtttca tgcacagttg caatattttc ttcaaaaata aaactctgta caaactttgg     7980

gcccgattca taagaaaaag aagtttgcta ttaacacggg atttttttaa tatacttttt     8040

ttggtctaaa tttgaaatta cttgcttccc aaattaaata aatttcatct catttttttc     8100

cctaaaccag cacccatctg ccttttattc cccaaagagt tacctttccc agattagggg     8160

gatggtatgt ggggagcaga tagcggaaat gcttagaaag ataaggggga ccacccacag     8220

ctggtcgtga gaacagggag acagtgtgtg ggggtgggac ctcatctgtg tgcctggtat     8280

cctgagtttt acatgtagat gcattcgcct atttgattca gaaaaataaa ctttcccaaa     8340

atgtgtctga accacaagag catacagtgg aagtgctacc tctaatctaa ccagagcacc     8400

ttcatggtgg aagacaccca ccaggtcata caatgtgaac ttttgtatct ctgcagtggt     8460

ttcaaggaca aatagtgtcc aatgtattgg gccatttttc ctgctgtttt tatactcaac     8520

ttctcaaaat gaaaaaagct tttatttttc ctttgactta tttgtgttgt tcttattttt     8580

taaattttta ttttttgata atagtctgta agttagcctt tttgggtttt tttttttttt     8640

ttttggcttt tttttttgtt tgtttttttt tcttttgaca ttgcaaccga aggtcataag     8700

gccgctagct ccgctgggac agaggcttga gagaactaac ggctcggtgc cttctccctg     8760

gtctcagacc atcgtctctg cactgcgaag gcatttggta gcctcgccac tgagatacta     8820

actagaccta gactaggagc tttatcaggt tctaggaggt cctttaggaa gactctcaaa     8880

ggcaaatccc tgatcccccg ccccaccctt agccctgccc tctcaccaga gcaaaattca     8940

ctggggactt ttcccaccac acatggaaat ctgtccactc ggaatacctc tgttttccat     9000

ttcaaattgt agggggaggg gatggaacac ttccagtgat ggtaagagat ctgttatgaa     9060

acgaaacacc ccccgtgtta ataacttggt ctgaaatctg tttttatgag ccgggccccc     9120

tgtgcctcta gtatacttgt attgactctc atagttaccc ttttagtttt actgtgttct     9180

gtgaaaattt gtaattggtt gagaatcact gtgggcgtcc attcttattc aactaaatct     9240

ccacaggttt tttgagctgg tgtggattag tttaactctt gtattcaacc attagtgcta     9300

ccaccttctc acattacaat acaattactg gaagcaagta ctgcatttcc tatgcaacaa     9360

aaaaggaaaa ataaaaaatt gctaatgcta aaaaaaaaaa aaa                       9403


<210>  1509
<211>  9339
<212>  DNA
<213>  homo sapiens

<400>  1509
gtacaatcca aagcacgcaa ggcaaaacca gagcgaatct gagaaccagc cagcccgggt       60

tggatcgctt tcaaaagaga gagtgagagc gagcgagcga gcgagcgaga gcgagacagt      120

gagagaggga gagagcgcgc cttgcaattg caaaagcctt ctgatttgga gttaaaaaaa      180

aaattctcca agaagcctgc aattggccaa cagcttttta aaaaatctct tccgggtttt      240

caacggttcc aagtttattt agatattttt taaatgcaaa aaaaagggga caacaaatga      300

agcaattcgt ctgagcattt taaagtttct cacgtactct ttttacattg caatggatga      360

atttcatcct ttcatcgaag cacttctgcc ccacgtccga gcctttgcct acacatggtt      420

caacctgcag gcccgaaaac gaaaatactt caaaaaacat gaaaagcgta tgtcaaaaga      480

agaagagaga gccgtgaagg atgaattgct aagtgaaaaa ccagaggtca agcagaagtg      540

ggcatctcga cttctggcaa agttgcggaa agatatccga cccgaatatc gagaggattt      600

tgttcttaca gttacaggga aaaaacctcc atgttgtgtt ctttccaacc cagaccagaa      660

aggcaagatg cgaagaattg actgcctccg ccaggcagat aaagtctgga ggttggacct      720

tgttatggtg attttgttta aaggtattcc gctggaaagt actgatggcg agcgccttgt      780

aaagtcccca caatgctcta atccagggct ctgtgtccaa ccccatcaca taggggtttc      840

tgttaaggaa ctcgatttat atttggcata ctttgtgcat gcagcagatt caagtcaatc      900

tgaaagtccc agccagccaa gtgacgctga cattaaggac cagccagaaa atggacattt      960

gggcttccag gacagttttg tcacatcagg tgtttttagt gtcactgagc tagtaagagt     1020

gtcacagaca ccaatagctg caggaactgg cccaaatttt tctctctcag atttggaaag     1080

ttcttcatac tacagcatga gtccaggagc aatgaggagg tctttaccca gcacatcctc     1140

tacgagctcc acaaagcgcc tcaagtctgt ggaggatgaa atggacagtc ctggtgagga     1200

gccattttat acaggccaag ggcgctcccc aggaagtggc agtcagtcaa gtggatggca     1260

tgaagtggag ccaggaatgc catctccaac cacactgaag aagtcggaga agtctggttt     1320

cagcagcccc tccccttcac agacctcctc cctgggaacg gcgttcacac agcatcaccg     1380

acctgtcatt acaggaccca gagcaagtcc gcatgcaaca ccatcgactc ttcatttccc     1440

gacatcaccc attatccagc agcctgggcc ttacttctca cacccagcca tccgctatca     1500

ccctcaggag acgctgaaag aatttgtcca acttgtctgc cctgatgctg gtcagcaggc     1560

tggacaggtg gggttcctca atcccaatgg gagcagccaa ggcaaggtgc acaacccatt     1620

ccttcccacc ccaatgttgc caccgccacc gccaccaccg atggccaggc ctgtgcctct     1680

gccggtgcca gacacaaagc ctccaaccac gtcaacagaa ggaggtgcag cctcccccac     1740

gtcaccaacc tactcgacac ccagcacctc ccccgcaaac cgattcgtca gtgttggacc     1800

acgggatcca agctttgtaa atatccctca acagacacag tcctggtacc tgggataaaa     1860

gttgcagcgt cccaccatcc accagacaga ccacctgacc ccttctcaac tctgtaacat     1920

ggacgcaacc tcaacccagc gcagttacaa cttcactatc agcggaaggg gagaaaaacc     1980

gattcaaatc aacttgtaca tggaaacagc aagcattatg gtcaaacagc aaaggccata     2040

accttttggg attttttttt ttttaaaata ctttagggac tgttgtaatt tctcatatgg     2100

tgctggaaat ggttgggctt tgtaacattt gaagtgtttc catggtagcg tgagcattag     2160

gtgacgtggc tagcggagga ctacccttgc tcactgactt cctgttgtaa cacactttcc     2220

ttacggagcc tggctgtttc acagtatttc atgaatttac ccacacaggt gtgatcctcc     2280

ttgagcattg aggaggcaca tggagaacta aatcttttgt agtagctgag atctgcaata     2340

tataacggga cagtcaaagg gcaatgtttt tctgtaacat attggaaaaa gaaaatgcag     2400

ttatattcct tttttatttg ttcctttagt ttgttttggt tcagcagtca gcagttaagt     2460

atataacatg gcccgcaagg acaatgaatc cactcacatt gcagaacaat tccgaaaatg     2520

gcaaactact actactactg ttcagttttt taaaagtttt gaaatgctgc acttacattt     2580

aaaaaaacaa caacaacatt ttttcaacaa tttcaacaat gacacaaaaa ttcacatgga     2640

aatggggaag atggtctgtt ttgacagaaa ctgacaggaa tcaatcaaaa caatcgaatt     2700

ttgaattgag taaagtgcaa tttcattgga tagctaaata tctttgtaag atagagattg     2760

ttgaaaattc tatttttgtt tttctagtcc tttcacccca ggactctaaa ttattggggt     2820

aaaaaacagc cttgcaagaa aaaggggagc tatttttgct ttttatgttt tttattgtta     2880

aacttgtatc cctttaaaaa ctgaaggaaa ttaaaaaaaa aaaacaaaaa aacaaatcta     2940

atggtgcttt taccacaata tgttaactac attaaatgct aattaattat tttctgttat     3000

caaagcacat gactaaaatg aaatcatggt atctgttaat tttataagct agaagtcact     3060

ataatggatt acgccaattc taaaaaattt tacacctatc tggcatcata ggatttatca     3120

gttatcagac acctcattgt accagagatt gtccagaagt tttaaagacc tttgcatccc     3180

tgaactgggc tatgggaaat aataatagta ataataataa taataataat gatgaaacca     3240

atactgacac aaatgctggt gcccattcag atcaagggta cttgttaggg aaaaaaaaaa     3300

aagtttgcac ccccaaacgt cctgtatctt atgaaaaaaa aaacaaaaaa caaaaacaaa     3360

aaaaaaacac aaaaaaccac agaaacaaaa acaaaaaaaa gtgcaagtga tttttctacc     3420

agacagcgaa gcaccccttt gcttcccatg cgacttcaag aaggtttcct atactataca     3480

tatatatacg ttctggttgg caagccctgc tgatcagaga aagtctctgc atgttctagt     3540

gttagtaact aatttttata tagttaatgt aggataaagt agagtgcatt aagacacaat     3600

attgtaatcc ctactctagg cacttgcctt taaactatgt ttttcagccc ttcagaaggg     3660

ttctactact gtcctataca atcaagtaac tgaaattctt gggaagacac tttgctcctc     3720

atctttctcc ccgaaacaat gttgttttgt tttgtttttt ttccttaatt tgcacgaaaa     3780

caaaaattcc atatcaatgt gccttgccct ggatagcgat tatttgtgga attgttgcac     3840

atgctcctct attgaaaggg gtttttccct agtcaagcat ttggagacac tttttgtaaa     3900

tgtgactttt atgtcagcca tcgtcagttt caacatctag aactaaatag aaagctagtt     3960

gttccgcaga taggagtagt ctttattgtc ctgtacggtc ggtggcagtg ctattctgag     4020

atctgtagat gcttagaata tcagtatttt ggatgttgct gcattttaca atttatttgg     4080

agtcttcctt tattttcccc cagatatatg aaaatatgca atacctgctt atatcatgta     4140

gaaaagctta gcaattatta atttttcttt tatttttttt tatttgacca aagtcggtgc     4200

tgcacttgac gcagtgtgtt ttaggtgttt gtctttgtac ttttttgtga tttttgaatg     4260

cacgtgcgca ggaagggctc ctcttagaga agcagtcaaa ctgtgaagca ctaagctgac     4320

cctgcttcaa gcaattttgt ttttacaact gttcctttca caagcaagcc ttaaaaaaaa     4380

aaaagacaac ttcctttttc ttcagctccc acaccccatt tttcttagca gactgcagtc     4440

aatccacatt caataaaaag tatataatgc ccatttttat atgcacgttt ttaaacttcc     4500

aagttctgaa aattgtttac tggttatctc tatttaagga aaaaaaaata aaataaaaca     4560

ttttggattt tcatatgtgt ctgataagtg gttgaatagt cgtttggcgc tgttgtatgg     4620

tgtgattgtc agtgtatggt gtcacttcct atagccagcc agcatacttt gccttcccct     4680

atagcactta gctgggcatt actttattat gacatatgtg cactaaaaaa tgaaaaaaag     4740

gaaaaaaaga aaaaaaaaaa gaaaaaatag cagctttcag tgcttcacag tgaagggaaa     4800

aaagcctaga caaacatttt gtcagaacct tgcaataagc caaggtatta ccagtaaatt     4860

ggttgtatat acaataaaat tgcacccttt tttaaacaaa acaaactaag caatagtttg     4920

ggcagtttta gttgttttta gtgagcatgt tgtagtcatg actgcaaaga gagagaataa     4980

actgcccgct cagaagatat gtaatttgta ttgttgtata gttttattga ttacactgat     5040

ttattctacc ctattttata atgcaggact tttgtaatgt tgtttaaatg aggaaaaatt     5100

tctgtcaaat tagcctagta aaatttctga tcgttcatta taaaggcagc gttcatagaa     5160

ttgcttttct ttctttttac cccccctttg ggaactggat ttaagtttaa aactttcctg     5220

tttccttttt tttttttttt ttgtaagtat ttaaatacaa ttattttttt ctctcaatgg     5280

tatagcatat tcctatgctt gagaagtata ggtctactga aaaaccattg taaatggacg     5340

ttacaggtat gctgtatttt tgaaggtatt ttgttgtatt aagtttgatg aagctaaaat     5400

tagggaactc tgaacagatt tgcaggaaaa aatgttttaa aggctttaaa acattaggga     5460

ggcagtctag ggtgataacg aacaggggtt aagtattaaa tacacgaagt tacatttttg     5520

ttcatgtttc attgtccaga aagcagcagg aaactattca gttgtgatca agcaggaaaa     5580

aagaaacacc aacagttgcc agtgtttttg ctttttagct taaaagcata gtgaagatgc     5640

ttgaggaaga ctttgctacc tggggtgtgt agacagacag actgagagct atcagcattt     5700

gaaggcccag cccttgactc tgagacacat ttgaattttt tctttcccat caaatggcat     5760

taacaagatt gggcaaagat gagtccctca aatttctgtg ttttttgttt gtttgtttgt     5820

ttgttttttc tttgggaact gaagtcagag gcacgaacac taactcttag catttttctg     5880

tagacttttt cttctggccc ttgtccctgc cagcaaaacg ccccttttct gatcattcgt     5940

gcgcagaggg cctcccagta atgccacgct ctccatgcta gagagccttc tctttcctct     6000

gaggtttgaa ctgatgttct gtgtcttcac accctggcat gacagttacg tgtggtcagc     6060

ccgctcccca ggcccgtccc tgccgccgcc aggtgtgggc tctaggcagg ccgacaaggt     6120

tacacctccc agagcttgtg atcttcattt tctgacagtc aaagtgtgaa ggaacccaga     6180

cttccccgag ccacggtgtt cagtcagccc acaggaatat gcaagaccca tctccaaaag     6240

tttgtctttg attttttcca agcccttagc cccataagct ttgaatcctg tagttacagt     6300

ggcataaagg actgacaaaa cctggataag gaaaaacctt ttttttctat gaattttttt     6360

tgttttttag gggaaaggga ttctaagaat gtcatttaat gtactttgca tcatgtctct     6420

agaaatatct ttgtccatag tggtggtgga gtctctctct ctctctctct ttttgtttgc     6480

ttctgttttc tttcttgtct tcattctttc ttttcttttt tatttctggt agcaggcctc     6540

catagaacaa atctaaaaca caaccaccat agtaatgtaa ggagagcttc agtggcacct     6600

caaaacccac ccttcgagat ctgtccaaag acagtctcag aaagctgcac tgcccaccgg     6660

ctcagctttc attcaaaaag gcttccaagg ccaattctgt cttgaagtca atgcatgtat     6720

ttactgtttg acagtaaacc cgctctgcct tctccacgtc caaggctgtg cattcgtcta     6780

attagcgtcg tgtatgtttt ccttttattt tttccaataa aaaagcagtg ggatgaaaat     6840

tgctttgata tatagcaggt aacattgaag ctattccata gcacttaact gtagtgaata     6900

ctgtgtcacc aattttgaaa tcaatttaat gtttaatgca aatccattac atggtgctat     6960

tataggctga caaaatgatt tacacaaatg tgacaacttg ggctcaattc actctgcttt     7020

ccaacagtgt aaatgcatag cagtgtttat ctgcatgaga actatgcact aatctatctg     7080

aagaaaaaaa ctatatcaac tttggtatct actttccgtt tacttcaatc cttgcctttt     7140

tggtcattgt tataatgcca gctttaggac agaaagaatt ataagaaaac cagcataata     7200

cctgatatat taaaatgtag tgcctgtgaa atctgtatta tattgctctt ctgaagtaag     7260

atttttctac accggtagcc ttcgctgtct gtcagtcagg accttctggt ataggtgatg     7320

taaaataacc gtacaatatt aatgcatgcg attccataat gcttagtgaa ctgtatgaat     7380

attactcaaa gttatgttag tctttttttc cgacttggtt cttgtcagct aggtttaaag     7440

gtatttcact gagaacgcaa attctgtctt ttcttgattt cggctgtttt cagtattttg     7500

gaggtataca tttacttaaa ttcagtatta ctcgtgtttt gtttttgttt ttgttttttg     7560

ttttcttttt cctaggggac aagcatgggt gtttgatttc agaaatcagt acctggcgag     7620

atttttgtct caaaacgact atttgaattt caagaactgt gctgcgaaga cactctgaga     7680

acatttgcaa gtcaggggca ttttccttga cccttgactg atgctatgcg gagactgata     7740

cattttctta atggacaatg ttcaagccag gtacccatgc ttgatctgtc ttcacaccag     7800

acctcctcat attaaaagga aaaataagaa aaaaaatgta agaaatcaca tggctattta     7860

gtttcatgca cagttgcaat attttcttca aaaataaaac tctgtacaaa ctttgggccc     7920

gattcataag aaaaagaagt ttgctattaa cacgggattt ttttaatata ctttttttgg     7980

tctaaatttg aaattacttg cttcccaaat taaataaatt tcatctcatt tttttcccta     8040

aaccagcacc catctgcctt ttattcccca aagagttacc tttcccagat tagggggatg     8100

gtatgtgggg agcagatagc ggaaatgctt agaaagataa gggggaccac ccacagctgg     8160

tcgtgagaac agggagacag tgtgtggggg tgggacctca tctgtgtgcc tggtatcctg     8220

agttttacat gtagatgcat tcgcctattt gattcagaaa aataaacttt cccaaaatgt     8280

gtctgaacca caagagcata cagtggaagt gctacctcta atctaaccag agcaccttca     8340

tggtggaaga cacccaccag gtcatacaat gtgaactttt gtatctctgc agtggtttca     8400

aggacaaata gtgtccaatg tattgggcca tttttcctgc tgtttttata ctcaacttct     8460

caaaatgaaa aaagctttta tttttccttt gacttatttg tgttgttctt attttttaaa     8520

tttttatttt ttgataatag tctgtaagtt agcctttttg ggtttttttt tttttttttt     8580

ggcttttttt tttgtttgtt tttttttctt ttgacattgc aaccgaaggt cataaggccg     8640

ctagctccgc tgggacagag gcttgagaga actaacggct cggtgccttc tccctggtct     8700

cagaccatcg tctctgcact gcgaaggcat ttggtagcct cgccactgag atactaacta     8760

gacctagact aggagcttta tcaggttcta ggaggtcctt taggaagact ctcaaaggca     8820

aatccctgat cccccgcccc acccttagcc ctgccctctc accagagcaa aattcactgg     8880

ggacttttcc caccacacat ggaaatctgt ccactcggaa tacctctgtt ttccatttca     8940

aattgtaggg ggaggggatg gaacacttcc agtgatggta agagatctgt tatgaaacga     9000

aacacccccc gtgttaataa cttggtctga aatctgtttt tatgagccgg gccccctgtg     9060

cctctagtat acttgtattg actctcatag ttaccctttt agttttactg tgttctgtga     9120

aaatttgtaa ttggttgaga atcactgtgg gcgtccattc ttattcaact aaatctccac     9180

aggttttttg agctggtgtg gattagttta actcttgtat tcaaccatta gtgctaccac     9240

cttctcacat tacaatacaa ttactggaag caagtactgc atttcctatg caacaaaaaa     9300

ggaaaaataa aaaattgcta atgctaaaaa aaaaaaaaa                            9339


<210>  1510
<211>  1830
<212>  DNA
<213>  homo sapiens

<400>  1510
ccgcccctca ccaacatggc cgcgggctgg aagtgcgcat gagcagctgt ctatggagat       60

acctaggccg ggagagggag aacacagttg gagaaaatcg gcagctgaga cggccttggc      120

cggacttagc actcaggcct gtgaatcagg agatacaaag acctccaaaa aaggaccagt      180

tcctcggatg tgccccctca cagagagatg aaggggcagc agaaaacagc tgaaacggaa      240

gaggggacag tgcagattca ggaaggtgca gtggctactg gggaagaccc aaccagtgtg      300

gctattgcca gcatccagtc agctgccacc ttccctgacc ccaacgtcaa gtacgtcttc      360

cgaactgaga atgggggcca ggtgatgtac agggtgatcc aggtgtctga ggggcagctg      420

gatggccaaa ctgagggaac tggcgccatc agtggctacc ctgccactca atccatgacc      480

caggcggtga tccagggtgc tttcaccagt gatgatgcag ttgacacgga ggggacagct      540

gctgagacgc actatactta cttccccagc acggcagtgg gagatggggc agggggtacc      600

acatcgggga gtacagctgc tgttgttact acccagggct cagaggcact gctggggcag      660

gcgacccctc ctggcactgg tcaattcttt gtgatgatgt caccacaaga agtactgcag      720

ggaggaagcc agcgctcaat tgcccctagg actcaccctt attccccgaa gtcagaagct      780

ccccggacga ctcgggatga gaaacgcagg gctcagcata atgaagtgga gcgtcgccgc      840

cgagacaaga tcaacaactg gatcgtgcag ctctccaaga taatcccaga ctgctctatg      900

gagagcacca agtctggcca gagtaaaggt gggattctat ccaaagcttg tgattatatc      960

caggagcttc ggcagagtaa ccaccgcttg tctgaagaac tgcagggact tgaccaactg     1020

cagctggaca atgacgtgct tcgacaacag gtggaagatc ttaaaaacaa gaatctgctg     1080

cttcgagctc agttgcggca ccacggatta gaggtcgtca tcaagaatga cagcaactaa     1140

ctatggggat tcaggggctt tgggcccaag aactgcagat agcccaggag caacagccta     1200

atcccgtgcc cctttccttc actgccccac ttctggcatg ggacaggggg aagttcagaa     1260

ggtgtgtcct tgaactgagg ccctgtgata tggcggcctg cagtggtgtg aaacacacaa     1320

tgtggacgtg cactgacagc cttgcccacc cccaccatgc agcccctggg cccttgtgct     1380

cctctcgcac aatgcatgtg ctgtctccat gctggatact ggacacacta aactctgggg     1440

cttgtcctgt gcttgcttag agtgcccagc agaggtttgc tgacaggtga tgctctggct     1500

tgccccagga ctctggcact tccattggtt cttcctttcc ctggagctga ggtttagatg     1560

tgcaacctgt ggctcagggg agcaagctta cacaagaagt gagggaagga tgtttagcag     1620

tggctggtgc ccatgaagag gagattggcc agtgagaagc tgaggcctat gcagacatct     1680

ctggagccag agagaacaac aggcaggggc ccacttgggg ccttccccct tgtgggggtc     1740

gttttttttt tttcttttct tttttttttt tttttttttt tttttttaag ataaaattgt     1800

tcaaagccaa aaaaaaaaaa aaaaaaaaaa                                      1830


<210>  1511
<211>  1799
<212>  DNA
<213>  homo sapiens

<400>  1511
ccgcccctca ccaacatggc cgcgggctgg aagtgcgcat gagcagctgt ctatggagat       60

acctaggccg ggagagggag aacacagttg gagaaaatcg gcagctgaga cggccttggc      120

cggacttagc actcaggcct gtgaatcagg agatacaaag acctccaaaa aaggaccagt      180

tcctcggatg tgccccctca cagagagatg aaggggcagc agaaaacagc tgaaacggaa      240

gaggggacag tgcagattca ggaaggtgca gtggctactg gggaagaccc aaccagtgtg      300

gctattgcca gcatccagtc agctgccacc ttccctgacc ccaacgtcaa gtgatgtaca      360

gggtgatcca ggtgtctgag gggcagctgg atggccaaac tgagggaact ggcgccatca      420

gtggctaccc tgccactcaa tccatgaccc aggcggtgat ccagggtgct ttcaccagtg      480

atgatgcagt tgacacggag gggacagctg ctgagacgca ctatacttac ttccccagca      540

cggcagtggg agatggggca gggggtacca catcggggag tacagctgct gttgttacta      600

cccagggctc agaggcactg ctggggcagg cgacccctcc tggcactggt caattctttg      660

tgatgatgtc accacaagaa gtactgcagg gaggaagcca gcgctcaatt gcccctagga      720

ctcaccctta ttccccgaag tcagaagctc cccggacgac tcgggatgag aaacgcaggg      780

ctcagcataa tgaagtggag cgtcgccgcc gagacaagat caacaactgg atcgtgcagc      840

tctccaagat aatcccagac tgctctatgg agagcaccaa gtctggccag agtaaaggtg      900

ggattctatc caaagcttgt gattatatcc aggagcttcg gcagagtaac caccgcttgt      960

ctgaagaact gcagggactt gaccaactgc agctggacaa tgacgtgctt cgacaacagg     1020

tggaagatct taaaaacaag aatctgctgc ttcgagctca gttgcggcac cacggattag     1080

aggtcgtcat caagaatgac agcaactaac tatggggatt caggggcttt gggcccaaga     1140

actgcagata gcccaggagc aacagcctaa tcccgtgccc ctttccttca ctgccccact     1200

tctggcatgg gacaggggga agttcagaag gtgtgtcctt gaactgaggc cctgtgatat     1260

ggcggcctgc agtggtgtga aacacacaat gtggacgtgc actgacagcc ttgcccaccc     1320

ccaccatgca gcccctgggc ccttgtgctc ctctcgcaca atgcatgtgc tgtctccatg     1380

ctggatactg gacacactaa actctggggc ttgtcctgtg cttgcttaga gtgcccagca     1440

gaggtttgct gacaggtgat gctctggctt gccccaggac tctggcactt ccattggttc     1500

ttcctttccc tggagctgag gtttagatgt gcaacctgtg gctcagggga gcaagcttac     1560

acaagaagtg agggaaggat gtttagcagt ggctggtgcc catgaagagg agattggcca     1620

gtgagaagct gaggcctatg cagacatctc tggagccaga gagaacaaca ggcaggggcc     1680

cacttggggc cttccccctt gtgggggtcg tttttttttt ttcttttctt tttttttttt     1740

tttttttttt ttttttaaga taaaattgtt caaagccaaa aaaaaaaaaa aaaaaaaaa      1799


<210>  1512
<211>  4551
<212>  DNA
<213>  homo sapiens

<400>  1512
atcgccggag acgcctgcgg cggccccgga gacaccggaa ggagccgcgg ctgctgcggg       60

aagtggccag ttcaggaggc ggaccccccg agggcagcgc tgcggggccg ttttccggcc      120

ctcctgacgc gacactgccc ctctccgaga gctgagaagg aaaagaggag cttgcggagg      180

tgcggctgca ggccgttgtt ggtcgagctg gcgggtcccg cgggccaggc cgtggagagc      240

tcctgaagga agcactaaac atggaaagga acaaccggta ccagccactg caaaaacatg      300

ccaaattgta aagaccatcg atgttaggaa gaaactgcct caactaatga gcaaaataac      360

cagctaacat cgtaatgaca ggatcaaatt cacacataac gatattaacc ttaaaggtgt      420

tacctcattt tgaaagtctt gggaaacagg aaaaaattcc taacaaaatg tcagcttttc      480

gaaatcattg tccacatttg gattcagttg gtgaaataac aaaagaagat ttgatacaaa      540

aatcccttgg tacttgtcag gattgtaaag tccaaggacc aaatctttgg gcatgtctgg      600

agaatagatg ttcatatgtt ggctgtggtg aatcacaagt agatcacagc accatacatt      660

ctcaggagac aaagcattat ctaactgtga accttaccac tcttcgagta tggtgttatg      720

cttgcagcaa agaagtattt ttggatagga aattaggaac tcagccttca ttgcctcatg      780

taagacaacc tcaccaaata caagaaaaca gtgtccagga ttttaaaata cccagtaata      840

caacattaaa aactcctctg gttgccgtat ttgatgatct ggatatagaa gcggatgaag      900

aagatgaact tagggccaga ggtcttacag gtttgaaaaa tattggaaat acttgttaca      960

tgaatgcagc tttgcaggct ctttctaatt gcccaccttt gacacagttt tttcttgatt     1020

gtggaggact agctcgaaca gataagaaac ctgccatttg taaaagttat ctcaaactaa     1080

tgacagagct gtggcataaa agcaggccag gatctgttgt gcctactact ctgtttcaag     1140

gaattaaaac tgtaaatcca acatttcggg ggtattctca gcaggatgct caagaattcc     1200

ttcgatgttt aatggatttg cttcatgaag aattgaaaga gcaagtcatg gaagtagaag     1260

aagatccgca aaccataacc actgaggaga caatggaaga agacaagagc cagtcggatg     1320

tagattttca gtcttgtgaa tcttgtagca acagtgatag agcagaaaat gaaaatggct     1380

ctagatgctt ttctgaagat aataatgaaa caacaatgtt aattcaggat gatgaaaaca     1440

attcagaaat gtcaaaggat tggcaaaaag agaagatgtg caataagatt aataaagtaa     1500

attctgaagg cgaatttgat aaagatagag actctatatc tgaaacagtc gacttaaaca     1560

accaggaaac tgtcaaagtg caaatacaca gcagagcttc agaatatatc actgatgtcc     1620

attcgaatga cctgtctaca ccacagatcc ttccatcaaa tgaaggtgtt aatccacgtt     1680

tatcggcaag ccctcctaaa tcaggcaatt tgtggccagg attggcacca ccacacaaaa     1740

aagctcagtc tgcatctcca aagagaaaaa aacagcacaa gaaatacaga agtgttattt     1800

cagacatatt tgatggaaca atcattagtt cagtgcagtg tctgacttgt gacagggtgt     1860

ctgtaaccct cgagaccttt caagatctgt ccttgccaat tcctggcaag gaagaccttg     1920

ctaagctgca ttcatcaagt catccaactt ctatagtcaa agcaggatca tgtggcgaag     1980

catatgctcc acaagggtgg atagcttttt tcatggaata tgtgaagagg tttgttgtct     2040

catgtgtccc tagctggttt tggggtccag tagtaacctt gcaagattgt cttgctgcct     2100

tctttgccag agatgaacta aaaggtgaca atatgtacag ttgtgaaaaa tgcaaaaagt     2160

tgagaaatgg agtgaagttt tgtaaagtac aaaactttcc tgagattttg tgcatccacc     2220

ttaaaagatt cagacatgaa ctaatgtttt ccaccaaaat cagtacccat gtttcatttc     2280

cgctagaagg cttggatctt cagccatttc ttgctaagga tagtccagct caaattgtga     2340

catatgatct tctgtcagtc atttgccatc atggaactgc aagtagtgga cactatatag     2400

cctactgccg aaacaatcta aataatctct ggtatgaatt tgatgatcag agtgtcactg     2460

aagtttcaga atctactgta caaaatgcag aagcttacgt tcttttctat aggaagagca     2520

gcgaagaggc acaaaaagag aggagaagga tatcaaattt attgaacata atggaaccaa     2580

gcctccttca gttttatatt tctcgacagt ggcttaataa atttaagacc tttgccgaac     2640

ctggccctat ttcaaataat gactttcttt gtattcatgg aggtgttcct ccaagaaaag     2700

ctggttatat tgaagacctg gttttgatgc tgcctcagaa catttgggat aacctatata     2760

gcaggtatgg tggaggacca gctgtcaacc atctgtacat ttgtcatact tgccaaattg     2820

aggcggagaa aattgaaaaa agaagaaaaa ctgaattgga aatttttatt cggcttaaca     2880

gagcgttcca aaaagaggac tctccagcta ctttttattg catcagtatg cagtggttta     2940

gagaatggga aagttttgtg aagggtaaag atggagatcc tccaggtcct attgacaata     3000

ctaagattgc agtcactaaa tgtggtaatg tgatgcttag gcaaggagca gattctggcc     3060

agatttctga agaaacatgg aattttctgc agtctattta tggtggaggg cctgaagtta     3120

tcctgcgacc tccggttgtt catgttgatc cagatatact tcaagcagaa gaaaaaattg     3180

aagtagaaac tcggtctttg taatttttag gatgtagaga gttctaatga ggaatcattt     3240

tcatgtgccc tgacatgtac acatgcgaaa acattcctaa aagcgtgttt atttgcttta     3300

ttttttttca tcatttatcc catttatttc ttcttagtgg gcattatgga agaatatatt     3360

aaaatgtgta atataccaca ggttggtata tttagtttta aatacttacc ataaagtctt     3420

tcagtgtaat ttttttttga gacagagtct tgctttgtca cccaggctgg agtgctgtgg     3480

tgttacctca gctcactgca gcctccacct cctgggttca agcgattctc ctgcctcagc     3540

ctctcgagta gctgggatta caggcacctg ccaccatgcc cggctaattt ttgtatttta     3600

gtagagatgg ggtttcacca tgttggccag gctagtctca aactcctgac ctcaggtgat     3660

ccacccacct cggcctccca aagtgctggg attacaggtg tgagccacag cgcctggccc     3720

agtgtaatat ttttgaaaga ggagggacaa ttgtgaaatc agtaggttat ctttaatctt     3780

tacactacat gcagatccat agtatccttt gtagtgttgt aaatactttt gctttgaaaa     3840

ctttttcatt gtcctaaatc accctgactc tgaccagtct ttcagttctc caaaagccca     3900

atttaattgt atagttttgt catggcttca tataataaag agcctatttt aagttgaaag     3960

tagtagtcag aaaattgtta atttcctaaa gctcaggaaa ctagggtgtc actttttttg     4020

cactgcagca tatacactaa ctagcttatt aaaatttaca aaatgtcttt ttgaatgtat     4080

caaggatata tttagtttga gtggaatttg tcagcagata tcagtaactt attgccgctt     4140

atattgtaca atgttaaact tcaattcctg taacctggtt agtattaatg tcagtgacta     4200

aaaaacttag agttagtttt agggcacttt ttattttgag agcatgaagt gtggaatgtg     4260

tcactacgat tgttgataaa gctgaggcca cttgcaactt gattttttaa atgaaataga     4320

taaagtcttt ttgaataata tagtatgcac tgctatttgc ttgattatgt aatgtcaaaa     4380

gtttaactat attccaagta caaaaacata ctggattaca ttgaggatgt tgaatagcat     4440

tcatgatggc tttgttttgg tttggggcag ctgtcaccag ctaaagcaat gttgttaaaa     4500

ttagctcaat aaaaatgtct ttaaaatgta aaaaaaaaaa aaaaaaaaaa a              4551


<210>  1513
<211>  4372
<212>  DNA
<213>  homo sapiens

<400>  1513
atcgccggag acgcctgcgg cggccccgga gacaccggaa ggagccgcgg ctgctgcggg       60

aagtggccag ttcaggaggc ggaccccccg agggcagcgc tgcggggccg ttttccggcc      120

ctcctgacgc gacactgccc ctctccgaga gctgagaagg aaaagaggag cttgcggagg      180

tgcggctgca ggccgttgtt ggtcgagctg gcgggtcccg cgggccaggc cgtggaggtg      240

ttacctcatt ttgaaagtct tgggaaacag gaaaaaattc ctaacaaaat gtcagctttt      300

cgaaatcatt gtccacattt ggattcagtt ggtgaaataa caaaagaaga tttgatacaa      360

aaatcccttg gtacttgtca ggattgtaaa gtccaaggac caaatctttg ggcatgtctg      420

gagaatagat gttcatatgt tggctgtggt gaatcacaag tagatcacag caccatacat      480

tctcaggaga caaagcatta tctaactgtg aaccttacca ctcttcgagt atggtgttat      540

gcttgcagca aagaagtatt tttggatagg aaattaggaa ctcagccttc attgcctcat      600

gtaagacaac ctcaccaaat acaagaaaac agtgtccagg attttaaaat acccagtaat      660

acaacattaa aaactcctct ggttgccgta tttgatgatc tggatataga agcggatgaa      720

gaagatgaac ttagggccag aggtcttaca ggtttgaaaa atattggaaa tacttgttac      780

atgaatgcag ctttgcaggc tctttctaat tgcccacctt tgacacagtt ttttcttgat      840

tgtggaggac tagctcgaac agataagaaa cctgccattt gtaaaagtta tctcaaacta      900

atgacagagc tgtggcataa aagcaggcca ggatctgttg tgcctactac tctgtttcaa      960

ggaattaaaa ctgtaaatcc aacatttcgg gggtattctc agcaggatgc tcaagaattc     1020

cttcgatgtt taatggattt gcttcatgaa gaattgaaag agcaagtcat ggaagtagaa     1080

gaagatccgc aaaccataac cactgaggag acaatggaag aagacaagag ccagtcggat     1140

gtagattttc agtcttgtga atcttgtagc aacagtgata gagcagaaaa tgaaaatggc     1200

tctagatgct tttctgaaga taataatgaa acaacaatgt taattcagga tgatgaaaac     1260

aattcagaaa tgtcaaagga ttggcaaaaa gagaagatgt gcaataagat taataaagta     1320

aattctgaag gcgaatttga taaagataga gactctatat ctgaaacagt cgacttaaac     1380

aaccaggaaa ctgtcaaagt gcaaatacac agcagagctt cagaatatat cactgatgtc     1440

cattcgaatg acctgtctac accacagatc cttccatcaa atgaaggtgt taatccacgt     1500

ttatcggcaa gccctcctaa atcaggcaat ttgtggccag gattggcacc accacacaaa     1560

aaagctcagt ctgcatctcc aaagagaaaa aaacagcaca agaaatacag aagtgttatt     1620

tcagacatat ttgatggaac aatcattagt tcagtgcagt gtctgacttg tgacagggtg     1680

tctgtaaccc tcgagacctt tcaagatctg tccttgccaa ttcctggcaa ggaagacctt     1740

gctaagctgc attcatcaag tcatccaact tctatagtca aagcaggatc atgtggcgaa     1800

gcatatgctc cacaagggtg gatagctttt ttcatggaat atgtgaagag gtttgttgtc     1860

tcatgtgtcc ctagctggtt ttggggtcca gtagtaacct tgcaagattg tcttgctgcc     1920

ttctttgcca gagatgaact aaaaggtgac aatatgtaca gttgtgaaaa atgcaaaaag     1980

ttgagaaatg gagtgaagtt ttgtaaagta caaaactttc ctgagatttt gtgcatccac     2040

cttaaaagat tcagacatga actaatgttt tccaccaaaa tcagtaccca tgtttcattt     2100

ccgctagaag gcttggatct tcagccattt cttgctaagg atagtccagc tcaaattgtg     2160

acatatgatc ttctgtcagt catttgccat catggaactg caagtagtgg acactatata     2220

gcctactgcc gaaacaatct aaataatctc tggtatgaat ttgatgatca gagtgtcact     2280

gaagtttcag aatctactgt acaaaatgca gaagcttacg ttcttttcta taggaagagc     2340

agcgaagagg cacaaaaaga gaggagaagg atatcaaatt tattgaacat aatggaacca     2400

agcctccttc agttttatat ttctcgacag tggcttaata aatttaagac ctttgccgaa     2460

cctggcccta tttcaaataa tgactttctt tgtattcatg gaggtgttcc tccaagaaaa     2520

gctggttata ttgaagacct ggttttgatg ctgcctcaga acatttggga taacctatat     2580

agcaggtatg gtggaggacc agctgtcaac catctgtaca tttgtcatac ttgccaaatt     2640

gaggcggaga aaattgaaaa aagaagaaaa actgaattgg aaatttttat tcggcttaac     2700

agagcgttcc aaaaagagga ctctccagct actttttatt gcatcagtat gcagtggttt     2760

agagaatggg aaagttttgt gaagggtaaa gatggagatc ctccaggtcc tattgacaat     2820

actaagattg cagtcactaa atgtggtaat gtgatgctta ggcaaggagc agattctggc     2880

cagatttctg aagaaacatg gaattttctg cagtctattt atggtggagg gcctgaagtt     2940

atcctgcgac ctccggttgt tcatgttgat ccagatatac ttcaagcaga agaaaaaatt     3000

gaagtagaaa ctcggtcttt gtaattttta ggatgtagag agttctaatg aggaatcatt     3060

ttcatgtgcc ctgacatgta cacatgcgaa aacattccta aaagcgtgtt tatttgcttt     3120

attttttttc atcatttatc ccatttattt cttcttagtg ggcattatgg aagaatatat     3180

taaaatgtgt aatataccac aggttggtat atttagtttt aaatacttac cataaagtct     3240

ttcagtgtaa tttttttttg agacagagtc ttgctttgtc acccaggctg gagtgctgtg     3300

gtgttacctc agctcactgc agcctccacc tcctgggttc aagcgattct cctgcctcag     3360

cctctcgagt agctgggatt acaggcacct gccaccatgc ccggctaatt tttgtatttt     3420

agtagagatg gggtttcacc atgttggcca ggctagtctc aaactcctga cctcaggtga     3480

tccacccacc tcggcctccc aaagtgctgg gattacaggt gtgagccaca gcgcctggcc     3540

cagtgtaata tttttgaaag aggagggaca attgtgaaat cagtaggtta tctttaatct     3600

ttacactaca tgcagatcca tagtatcctt tgtagtgttg taaatacttt tgctttgaaa     3660

actttttcat tgtcctaaat caccctgact ctgaccagtc tttcagttct ccaaaagccc     3720

aatttaattg tatagttttg tcatggcttc atataataaa gagcctattt taagttgaaa     3780

gtagtagtca gaaaattgtt aatttcctaa agctcaggaa actagggtgt cacttttttt     3840

gcactgcagc atatacacta actagcttat taaaatttac aaaatgtctt tttgaatgta     3900

tcaaggatat atttagtttg agtggaattt gtcagcagat atcagtaact tattgccgct     3960

tatattgtac aatgttaaac ttcaattcct gtaacctggt tagtattaat gtcagtgact     4020

aaaaaactta gagttagttt tagggcactt tttattttga gagcatgaag tgtggaatgt     4080

gtcactacga ttgttgataa agctgaggcc acttgcaact tgatttttta aatgaaatag     4140

ataaagtctt tttgaataat atagtatgca ctgctatttg cttgattatg taatgtcaaa     4200

agtttaacta tattccaagt acaaaaacat actggattac attgaggatg ttgaatagca     4260

ttcatgatgg ctttgttttg gtttggggca gctgtcacca gctaaagcaa tgttgttaaa     4320

attagctcaa taaaaatgtc tttaaaatgt aaaaaaaaaa aaaaaaaaaa aa             4372


<210>  1514
<211>  2956
<212>  DNA
<213>  homo sapiens

<400>  1514
atcgccggag acgcctgcgg cggccccgga gacaccggaa ggagccgcgg ctgctgcggg       60

aagtggccag ttcaggaggc ggaccccccg agggcagcgc tgcggggccg ttttccggcc      120

ctcctgacgc gacactgccc ctctccgaga gctgagaagg aaaagaggag cttgcggagg      180

tgcggctgca ggccgttgtt ggtcgagctg gcgggtcccg cgggccaggc cgtggagagc      240

tcctgaagga agcactaaac atggaaagga acaaccggta ccagccactg caaaaacatg      300

ccaaattgta aagaccatcg atgttaggaa gaaactgcct caactaatga gcaaaataac      360

cagctaacat cgtaatgaca ggatcaaatt cacacataac gatattaacc ttaaaggtgt      420

tacctcattt tgaaagtctt gggaaacagg aaaaaattcc taacaaaatg tcagcttttc      480

gaaatcattg tccacatttg gattcagttg gtgaaataac aaaagaagat ttgatacaaa      540

aatcccttgg tacttgtcag gattgtaaag tccaaggacc aaatctttgg gcatgtctgg      600

agaatagatg ttcatatgtt ggctgtggtg aatcacaagt agatcacagc accatacatt      660

ctcaggagac aaagcattat ctaactgtga accttaccac tcttcgagta tggtgttatg      720

cttgcagcaa agaagtattt ttggatagga aattaggaac tcagccttca ttgcctcatg      780

taagacaacc tcaccaaata caagaaaaca gtgtccagga ttttaaaata cccagtaata      840

caacattaaa aactcctctg gttgccgtat ttgatgatct ggatatagaa gcggatgaag      900

aagatgaact tagggccaga ggtcttacag gtttgaaaaa tattggaaat acttgttaca      960

tgaatgcagc tttgcaggct ctttctaatt gcccaccttt gacacagttt tttcttgatt     1020

gtggaggact agctcgaaca gataagaaac ctgccatttg taaaagttat ctcaaactaa     1080

tgacagagct gtggcataaa agcaggccag gatctgttgt gcctactact ctgtttcaag     1140

gaattaaaac tgtaaatcca acatttcggg ggtattctca gcaggatgct caagaattcc     1200

ttcgatgttt aatggatttg cttcatgaag aattgaaaga gcaagtcatg gaagtagaag     1260

aagatccgca aaccataacc actgaggaga caatggaaga agacaagagc cagtcggatg     1320

tagattttca gtcttgtgaa tcttgtagca acagtgatag agcagaaaat gaaaatggct     1380

ctagatgctt ttctgaagat aataatgaaa caacaatgtt aattcaggat gatgaaaaca     1440

attcagaaat gtcaaaggat tggcaaaaag agaagatgtg caataagatt aataaagtaa     1500

attctgaagg cgaatttgat aaagatagag actctatatc tgaaacagtc gacttaaaca     1560

accaggaaac tgtcaaagtg caaatacaca gcagagcttc agaatatatc actgatgtcc     1620

attcgaatga cctgtctaca ccacagatcc ttccatcaaa tgaaggtgtt aatccacgtt     1680

tatcggcaag ccctcctaaa tcaggcaatt tgtggccagg attggcacca ccacacaaaa     1740

aagctcagtc tgcatctcca aagagaaaaa aacagcacaa gaaatacaga agtgttattt     1800

cagacatatt tgatggaaca atcattagtt cagtgcagtg tctgacttgt gacagggtgt     1860

ctgtaaccct cgagaccttt caagatctgt ccttgccaat tcctggcaag gaagaccttg     1920

ctaagctgca ttcatcaagt catccaactt ctatagtcaa agcaggatca tgtggcgaag     1980

catatgctcc acaagggtgg atagcttttt tcatggaata tgtgaagagc tggttttggg     2040

gtccagtagt aaccttgcaa gattgtcttg ctgccttctt tgccagagat gaactaaaag     2100

gtgacaatat gtacagttgt gaaaaatgca aaaagttgag aaatggagtg aagttttgta     2160

aagtacaaaa ctttcctgag attttgtgca tccaccttaa aagattcaga catgaactaa     2220

tgttttccac caaaatcagt acccatgttt catttccgct agaaggcttg gatcttcagc     2280

catttcttgc taaggatagt ccagctcaaa ttgtgacata tgatcttctg tcagtcattt     2340

gccatcatgg aactgcaagt agtggacact atatagccta ctgccgaaac aatctaaata     2400

atctctggta tgaatttgat gatcagagtg tcactgaagt ttcagaatct actgtacaaa     2460

atgcagaagc ttacgttctt ttctatagga agagcagcga agaggcacaa aaagagagga     2520

gaaggatatc aaatttattg aacataatgg aaccaagcct ccttcagttt tatatttctc     2580

gacagtggct taataaattt aagacctttg ccgaacctgg ccctatttca aataatgact     2640

ttctttgtat tcatggaggt gttcctccaa gaaaagctgg ttatattgaa gacctggttt     2700

tgatgctgcc tcagaacatt tgggataacc tatatagcag gtatggtgga ggaccagctg     2760

tcaaccatct gtacatttgt catacttgcc aaattgaggc ggagaaaatt gaaaaaagaa     2820

gaaaaactga attggaaatt tttattcggg taaaaaagtg atgcttttca aattgatcta     2880

ggataaagat gaagacctga caattatcag agttatatga tattaataaa atgattagat     2940

gaaaaaaaaa aaaaaa                                                     2956


<210>  1515
<211>  2828
<212>  DNA
<213>  homo sapiens

<400>  1515
ctcgggccca cgtgagctgt agggaaacgc aggggcggct tctaggtgct gccgccgcca       60

ccgccaccac cacctccacc gccgcctcgg aacccaggcc tggggggcgg tggggccgcg      120

tatggagccc ccgccccccg gagctgccaa cattgccaac gccaccgcca cgctacacac      180

aggtacccct gggatggcgt gagcactccc ccagcgatgg acccatctgt gacgctgtgg      240

cagtttctgc tgcagctgct gagagagcaa ggcaatggcc acatcatctc ctggacttca      300

cgggatggtg gtgaattcaa gctggtggat gcagaggagg tggcccggct gtgggggcta      360

cgcaagaaca agaccaacat gaattacgac aagctcagcc gggccttgcg gtactactat      420

gacaagaaca tcatccgcaa ggtgagcggc cagaagttcg tctacaagtt tgtgtcctac      480

cctgaggtcg cagggtgctc cactgaggac tgcccgcccc agccagaggt gtctgttacc      540

tccaccatgc caaatgtggc ccctgctgct atacatgccg ccccagggga cactgtctct      600

ggaaagccag gcacacccaa gggtgcagga atggcaggcc caggcggttt ggcacgcagc      660

agccggaacg agtacatgcg ctcgggcctc tattccacct tcaccatcca gtctctgcag      720

ccgcagccac cccctcatcc tcggcctgct gtggtgctcc ccagtgcagc tcctgcaggg      780

gcagcagcgc ccccctcggg gagcaggagc accagtccaa gccccttgga ggcctgtctg      840

gaggctgaag aggccggctt gcctctgcag gtcatcctga ccccgcccga ggccccaaac      900

ctgaaatcgg aagagcttaa tgtggagccg ggtttgggcc gggctttgcc cccagaagtg      960

aaagtagaag ggcccaagga agagttggaa gttgcggggg agagagggtt tgtgccagaa     1020

accaccaagg ccgagccaga agtccctcca caggagggcg tgccagcccg gctgcccgcg     1080

gttgttatgg acaccgcagg gcaggcgggc ggccatgcgg cttccagccc tgagatctcc     1140

cagccgcaga agggccggaa gccccgggac ctagagcttc cactcagccc gagcctgcta     1200

ggtgggccgg gacccgaacg gaccccagga tcgggaagtg gctccggcct ccaggctccg     1260

gggccggcgc tgaccccatc cctgcttcct acgcatacat tgaccccggt gctgctgaca     1320

cccagctcgc tgcctcctag cattcacttc tggagcaccc tgagtcccat tgcgccccgt     1380

agcccggcca agctctcctt ccagtttcca tccagtggca gcgcccaggt gcacatccct     1440

tctatcagcg tggatggcct ctcgaccccc gtggtgctct ccccagggcc ccagaagcca     1500

tgactactac caccaccacc accacccctt ctggggtcac tccatccatg ctctctccag     1560

ccagccatct caaggagaaa catagttcaa ctgaaagact catgctctga ttgtggtggg     1620

gtggggatcc ttgggaagaa ttactcccaa gagtaactct cattatctcc tccacagaaa     1680

acacacagct tccacaactt ctctgttttc tgtcagtccc ccagtggccg cccttacacg     1740

tctcctactt caatggtagg ggcggtttat ttatttattt tttgaaggcc actgggagga     1800

gcctgaccta accttttagg gtggttagga catctccccc acctccccac ttttttcccc     1860

aagacaagac aatcgaggtc tggcttgaga acgacctttc tttctttatt tctcagcctg     1920

cccttgggga gatgagggag ccctgtctgc gtttttggat gtgagtagaa gagttagttt     1980

gttttgtttt attattcctg gccatactca ggggtccagg aagaatttgt accatttaat     2040

gggttgggag tcttggccaa ggaagaatca cacccttgga atagaaattt ccacctcccc     2100

aacctttctc tcagacagct tatccttttc aaccaacttt ttggccaggg aggaatgtcc     2160

cttttgttct tccccctgag aagccattcc tttgtctgcc aacctccctg gggtcctgcc     2220

tgtttcctcc caatggaggg tttttttggg gggtggtccc cgtctggggg gcccctccag     2280

ccagtactcc aggtctccct gtctctcccc cgctgccatt ttgatagtat aatctatttt     2340

taaatggggc ttttcaatag gggagaggga gtcatctctt cctatatttg gtggggtggg     2400

tgggaaggaa gggatttggg ggggaatctt cctgccgcct cccccactcc aagtgtttat     2460

ttttgatacc aaacatgaat tttcagttcc ctccctccca gccccccaat ttcctgcggg     2520

cgggtacaaa ggaccctttc aatgtccctg gagttgggag ggaggaatgg gggacataaa     2580

gcctgtcctg tctctattct aggcaagaga gagtgggttc aaaagactcc tgggctcacc     2640

tgttagcgct ggcccagccc aggccttggg acctgggggt tggtgatttg ggggacagtg     2700

ctacactcgt ctccactgtt tgttttactt ccccaaaatg gacctttttt ttttctaaag     2760

agtcccagag aatggggaat tgttcctgta aatatatatt tttcaaagtg ataaaaaaaa     2820

aaaaaaaa                                                              2828


<210>  1516
<211>  2398
<212>  DNA
<213>  homo sapiens

<400>  1516
agccccgccc tgccccgcgc cgccaagcgg ttcccgccct cgcccagcgc ccaggtagct       60

gcgaggaaac ttttgcagcg gctgggtagc agcacgtctc ttgctcctca gggccactgc      120

caggcttgcc gagtcctggg actgctctcg ctccggctgc cactctcccg cgctctccta      180

gctccctgcg aagcaggatg gccgggaccg tgcgcaccgc gtgcttggtg gtggcgatgc      240

tgctcagctt ggacttcccg ggacaggcgc agcccccgcc gccgccgccg gacgccacct      300

gtcaccaagt ccgctccttc ttccagagac tgcagcccgg actcaagtgg gtgccagaaa      360

ctcccgtgcc aggatcagat ttgcaagtat gtctccctaa gggcccaaca tgctgctcaa      420

gaaagatgga agaaaaatac caactaacag cacgattgaa catggaacag ctgcttcagt      480

ctgcaagtat ggagctcaag ttcttaatta ttcagaatgc tgcggttttc caagaggcct      540

ttgaaattgt tgttcgccat gccaagaact acaccaatgc catgttcaag aacaactacc      600

caagcctgac tccacaagct tttgagtttg tgggtgaatt tttcacagat gtgtctctct      660

acatcttggg ttctgacatc aatgtagatg acatggtcaa tgaattgttt gacagcctgt      720

ttccagtcat ctatacccag ctaatgaacc caggcctgcc tgattcagcc ttggacatca      780

atgagtgcct ccgaggagca agacgtgacc tgaaagtatt tgggaatttc cccaagctta      840

ttatgaccca ggtttccaag tcactgcaag tcactaggat cttccttcag gctctgaatc      900

ttggaattga agtgatcaac acaactgatc acctgaagtt cagtaaggac tgtggccgaa      960

tgctcaccag aatgtggtac tgctcttact gccagggact gatgatggtt aaaccctgtg     1020

gcggttactg caatgtggtc atgcaaggct gtatggcagg tgtggtggag attgacaagt     1080

actggagaga atacattctg tcccttgaag aacttgtgaa tggcatgtac agaatctatg     1140

acatggagaa cgtactgctt ggtctctttt caacaatcca tgattctatc cagtatgtcc     1200

agaagaatgc aggaaagctg accaccactg aaactgagaa gaaaatatgg cacttcaaat     1260

atcctatctt cttcctgtgt atagggctag acttacagat tggcaagtta tgtgcccatt     1320

ctcaacaacg ccaatataga tctgcttatt atcctgaaga tctctttatt gacaagaaag     1380

tattaaaagt tgctcatgta gaacatgaag aaaccttatc cagccgaaga agggaactaa     1440

ttcagaagtt gaagtctttc atcagcttct atagtgcttt gcctggctac atctgcagcc     1500

atagccctgt ggcggaaaac gacacccttt gctggaatgg acaagaactc gtggagagat     1560

acagccaaaa ggcagcaagg aatggaatga aaaaccagtt caatctccat gagctgaaaa     1620

tgaagggccc tgagccagtg gtcagtcaaa ttattgacaa actgaagcac attaaccagc     1680

tcctgagaac catgtctatg cccaaaggta gagttctgga taaaaacctg gatgaggaag     1740

ggtttgaaag tggagactgc ggtgatgatg aagatgagtg cattggaggc tctggtgatg     1800

gaatgataaa agtgaagaat cagctccgct tccttgcaga actggcctat gatctggatg     1860

tggatgatgc gcctggaaac agtcagcagg caactccgaa ggacaacgag ataagcacct     1920

ttcacaacct cgggaacgtt cattccccgc tgaagcttct caccagcatg gccatctcgg     1980

tggtgtgctt cttcttcctg gtgcactgac tgcctggtgc ccagcacatg tgctgcccta     2040

cagcaccctg tggtcttcct cgataaaggg aaccactttc ttattttttt ctattttttt     2100

ttttttgtta tcctgtatac ctcctccagc catgaagtag aggactaacc atgtgttatg     2160

ttttcgaaaa tcaaatggta tcttttggag gaagatacat tttagtggta gcatatagat     2220

tgtccttttg caaagaaaga aaaaaaacca tcaagttgtg ccaaattatt ctcctatgtt     2280

tggctgctag aacatggtta ccatgtcttt ctctctcact ccctcccttt ctatcgttct     2340

ctctttgcat ggatttcttt gaaaaaaaat aaattgctca aataaaaaaa aaaaaaaa       2398


<210>  1517
<211>  2281
<212>  DNA
<213>  homo sapiens

<400>  1517
agccccgccc tgccccgcgc cgccaagcgg ttcccgccct cgcccagcgc ccaggtagct       60

gcgaggaaac ttttgcagcg gctgggtagc agcacgtctc ttgctcctca gggccactgc      120

caggcttgcc gagtcctggg actgctctcg ctccggctgc cactctcccg cgctctccta      180

gctccctgcg aagcaggatg gccgggaccg tgcgcaccgc gtgcttggtg gtggcgatgc      240

tgctcagctt ggacttcccg ggacaggcgc agcccccgcc gccgccgccg gacgccacct      300

gtcaccaagt ccgctccttc ttccagagac tgcagcccgg actcaagtgg gtgccagaaa      360

ctcccgtgcc aggatcagat ttgcaagtat gtctccctaa gggcccaaca tgctgctcaa      420

gaaagatgga agaaaaatac caactaacag cacgattgaa catggaacag ctgcttcagt      480

ctgcaaaggc ctttgaaatt gttgttcgcc atgccaagaa ctacaccaat gccatgttca      540

agaacaacta cccaagcctg actccacaag cttttgagtt tgtgggtgaa tttttcacag      600

atgtgtctct ctacatcttg ggttctgaca tcaatgtaga tgacatggtc aatgaattgt      660

ttgacagcct gtttccagtc atctataccc agctaatgaa cccaggcctg cctgattcag      720

ccttggacat caatgagtgc ctccgaggag caagacgtga cctgaaagta tttgggaatt      780

tccccaagct tattatgacc caggtttcca agtcactgca agtcactagg atcttccttc      840

aggctctgaa tcttggaatt gaagtgatca acacaactga tcacctgaag ttcagtaagg      900

actgtggccg aatgctcacc agaatgtggt actgctctta ctgccaggga ctgatgatgg      960

ttaaaccctg tggcggttac tgcaatgtgg tcatgcaagg ctgtatggca ggtgtggtgg     1020

agattgacaa gtactggaga gaatacattc tgtcccttga agaacttgtg aatggcatgt     1080

acagaatcta tgacatggag aacgtactgc ttggtctctt ttcaacaatc catgattcta     1140

tccagtatgt ccagaagaat gcaggaaagc tgaccaccac tattggcaag ttatgtgccc     1200

attctcaaca acgccaatat agatctgctt attatcctga agatctcttt attgacaaga     1260

aagtattaaa agttgctcat gtagaacatg aagaaacctt atccagccga agaagggaac     1320

taattcagaa gttgaagtct ttcatcagct tctatagtgc tttgcctggc tacatctgca     1380

gccatagccc tgtggcggaa aacgacaccc tttgctggaa tggacaagaa ctcgtggaga     1440

gatacagcca aaaggcagca aggaatggaa tgaaaaacca gttcaatctc catgagctga     1500

aaatgaaggg ccctgagcca gtggtcagtc aaattattga caaactgaag cacattaacc     1560

agctcctgag aaccatgtct atgcccaaag gtagagttct ggataaaaac ctggatgagg     1620

aagggtttga aagtggagac tgcggtgatg atgaagatga gtgcattgga ggctctggtg     1680

atggaatgat aaaagtgaag aatcagctcc gcttccttgc agaactggcc tatgatctgg     1740

atgtggatga tgcgcctgga aacagtcagc aggcaactcc gaaggacaac gagataagca     1800

cctttcacaa cctcgggaac gttcattccc cgctgaagct tctcaccagc atggccatct     1860

cggtggtgtg cttcttcttc ctggtgcact gactgcctgg tgcccagcac atgtgctgcc     1920

ctacagcacc ctgtggtctt cctcgataaa gggaaccact ttcttatttt tttctatttt     1980

tttttttttg ttatcctgta tacctcctcc agccatgaag tagaggacta accatgtgtt     2040

atgttttcga aaatcaaatg gtatcttttg gaggaagata cattttagtg gtagcatata     2100

gattgtcctt ttgcaaagaa agaaaaaaaa ccatcaagtt gtgccaaatt attctcctat     2160

gtttggctgc tagaacatgg ttaccatgtc tttctctctc actccctccc tttctatcgt     2220

tctctctttg catggatttc tttgaaaaaa aataaattgc tcaaataaaa aaaaaaaaaa     2280

a                                                                     2281


<210>  1518
<211>  2167
<212>  DNA
<213>  homo sapiens

<400>  1518
agccccgccc tgccccgcgc cgccaagcgg ttcccgccct cgcccagcgc ccaggtagct       60

gcgaggaaac ttttgcagcg gctgggtagc agcacgtctc ttgctcctca gggccactgc      120

caggcttgcc gagtcctggg actgctctcg ctccggctgc cactctcccg cgctctccta      180

gctccctgcg aagcaggatg gccgggaccg tgcgcaccgc gtgcttggtg gtggcgatgc      240

tgctcagctt ggacttcccg ggacaggcgc agcccccgcc gccgccgccg gacgccacct      300

gtcaccaagt ccgctccttc ttccagagac tgcagcccgg actcaagtgg gtgccagaaa      360

ctcccgtgcc agaggccttt gaaattgttg ttcgccatgc caagaactac accaatgcca      420

tgttcaagaa caactaccca agcctgactc cacaagcttt tgagtttgtg ggtgaatttt      480

tcacagatgt gtctctctac atcttgggtt ctgacatcaa tgtagatgac atggtcaatg      540

aattgtttga cagcctgttt ccagtcatct atacccagct aatgaaccca ggcctgcctg      600

attcagcctt ggacatcaat gagtgcctcc gaggagcaag acgtgacctg aaagtatttg      660

ggaatttccc caagcttatt atgacccagg tttccaagtc actgcaagtc actaggatct      720

tccttcaggc tctgaatctt ggaattgaag tgatcaacac aactgatcac ctgaagttca      780

gtaaggactg tggccgaatg ctcaccagaa tgtggtactg ctcttactgc cagggactga      840

tgatggttaa accctgtggc ggttactgca atgtggtcat gcaaggctgt atggcaggtg      900

tggtggagat tgacaagtac tggagagaat acattctgtc ccttgaagaa cttgtgaatg      960

gcatgtacag aatctatgac atggagaacg tactgcttgg tctcttttca acaatccatg     1020

attctatcca gtatgtccag aagaatgcag gaaagctgac caccactatt ggcaagttat     1080

gtgcccattc tcaacaacgc caatatagat ctgcttatta tcctgaagat ctctttattg     1140

acaagaaagt attaaaagtt gctcatgtag aacatgaaga aaccttatcc agccgaagaa     1200

gggaactaat tcagaagttg aagtctttca tcagcttcta tagtgctttg cctggctaca     1260

tctgcagcca tagccctgtg gcggaaaacg acaccctttg ctggaatgga caagaactcg     1320

tggagagata cagccaaaag gcagcaagga atggaatgaa aaaccagttc aatctccatg     1380

agctgaaaat gaagggccct gagccagtgg tcagtcaaat tattgacaaa ctgaagcaca     1440

ttaaccagct cctgagaacc atgtctatgc ccaaaggtag agttctggat aaaaacctgg     1500

atgaggaagg gtttgaaagt ggagactgcg gtgatgatga agatgagtgc attggaggct     1560

ctggtgatgg aatgataaaa gtgaagaatc agctccgctt ccttgcagaa ctggcctatg     1620

atctggatgt ggatgatgcg cctggaaaca gtcagcaggc aactccgaag gacaacgaga     1680

taagcacctt tcacaacctc gggaacgttc attccccgct gaagcttctc accagcatgg     1740

ccatctcggt ggtgtgcttc ttcttcctgg tgcactgact gcctggtgcc cagcacatgt     1800

gctgccctac agcaccctgt ggtcttcctc gataaaggga accactttct tatttttttc     1860

tatttttttt tttttgttat cctgtatacc tcctccagcc atgaagtaga ggactaacca     1920

tgtgttatgt tttcgaaaat caaatggtat cttttggagg aagatacatt ttagtggtag     1980

catatagatt gtccttttgc aaagaaagaa aaaaaaccat caagttgtgc caaattattc     2040

tcctatgttt ggctgctaga acatggttac catgtctttc tctctcactc cctccctttc     2100

tatcgttctc tctttgcatg gatttctttg aaaaaaaata aattgctcaa ataaaaaaaa     2160

aaaaaaa                                                               2167


<210>  1519
<211>  7114
<212>  DNA
<213>  homo sapiens

<400>  1519
gcctccagtg actgtctcca ggatttctct cttcctattt caggaggact ctcacaggct       60

cccacagcct gtgttaagct gaggtttccc ctagatctcg tatatcccca acacatacct      120

ccacgcacac acatccccaa gaacctcgag ctcacaccaa cagacacacg cgcgcataca      180

cactcgctct cgcttgtcca tctccctccc gggggagccg gcgcgcgctc ccacctttgc      240

cgcacactcc ggcgagccga gcccgcagcg ctccaggatt ctgcggctcg gaactcggat      300

tgcagctctg aacccccatg gtggtttttt aaacacttct tttccttctc ttcctcgttt      360

tgattgcacc gtttccatct gggggctaga ggagcaaggc agcagccttc ccagccagcc      420

cttgttggct tgccatcgtc catctggctt ataaaagttt gctgagcgca gtccagaggg      480

ctgcgctgct cgtcccctcg gctggcagaa gggggtgacg ctgggcagcg gcgaggagcg      540

cgccgctgcc tctggcgggc tttcggcttg aggggcaagg tgaagagcgc accggccgtg      600

gggtttaccg agctggattt gtatgttgca ccatgccttc ttggatcggg gctgtgattc      660

ttcccctctt ggggctgctg ctctccctcc ccgccggggc ggatgtgaag gctcggagct      720

gcggagaggt ccgccaggcg tacggtgcca agggattcag cctggcggac atcccctacc      780

aggagatcgc aggggaacac ttaagaatct gtcctcagga atatacatgc tgcaccacag      840

aaatggaaga caagttaagc caacaaagca aactcgaatt tgaaaacctt gtggaagaga      900

caagccattt tgtgcgcacc acttttgtgt ccaggcataa gaaatttgac gaatttttcc      960

gagagctcct ggagaatgca gaaaagtcac taaatgatat gtttgtacgg acctatggca     1020

tgctgtacat gcagaattca gaagtcttcc aggacctctt cacagagctg aaaaggtact     1080

acactggggg taatgtgaat ctggaggaaa tgctcaatga cttttgggct cggctcctgg     1140

aacggatgtt tcagctgata aaccctcagt atcacttcag tgaagactac ctggaatgtg     1200

tgagcaaata cactgaccag ctcaagccat ttggagacgt gccccggaaa ctgaagattc     1260

aggttacccg cgccttcatt gctgccagga cctttgtcca ggggctgact gtgggcagag     1320

aagttgcaaa ccgagtttcc aaggtcagcc caaccccagg gtgtatccgt gccctcatga     1380

agatgctgta ctgcccatac tgtcgggggc ttcccactgt gaggccctgc aacaactact     1440

gtctcaacgt catgaagggc tgcttggcaa atcaggctga cctcgacaca gagtggaatc     1500

tgtttataga tgcaatgctc ttggtggcag agcgactgga ggggccattc aacattgagt     1560

cggtcatgga cccgatagat gtcaagattt ctgaagccat tatgaacatg caagaaaaca     1620

gcatgcaggt gtctgcaaag gtctttcagg gatgtggtca gcccaaacct gctccagccc     1680

tcagatctgc ccgctcagct cctgaaaatt ttaatacacg tttcaggccc tacaatcctg     1740

aggaaagacc aacaactgct gcaggcacaa gcttggaccg gctggtcaca gacataaaag     1800

agaaattgaa gctctctaaa aaggtctggt cagcattacc ctacactatc tgcaaggacg     1860

agagcgtgac agcgggcacg tccaacgagg aggaatgctg gaacgggcac agcaaagcca     1920

gatacttgcc tgagatcatg aatgatgggc tcaccaacca gatcaacaat cccgaggtgg     1980

atgtggacat cactcggcct gacactttca tcagacagca gattatggct ctccgtgtga     2040

tgaccaacaa actaaaaaac gcctacaatg gcaatgatgt caatttccag gacacaagtg     2100

atgaatccag tggctcaggg agtggcagtg ggtgcatgga tgacgtgtgt cccacggagt     2160

ttgagtttgt caccacagag gcccccgcag tggatcccga ccggagagag gtggactctt     2220

ctgcagccca gcgtggccac tccctgctct cctggtctct cacctgcatt gtcctggcac     2280

tgcagagact gtgcagataa tcttgggttt ttggtcagat gaaactgcat tttagctatc     2340

tgaatggcca actcacttct tttcttacac tcttggacaa tggaccatgc cacaaaaact     2400

taccgttttc tatgagaaga gagcagtaat gcaatctgcc tccctttttg ttttcccaaa     2460

gagtaccggg tgccagactg aactgcttcc tctttccttc agctatctgt ggggaccttg     2520

tttattctag agagaattct tactcaaatt tttcgtacca ggagattttc ttaccttcat     2580

ttgcttttat gctgcagaag taaaggaatc tcacgttgtg agggtttttt ttttctcatt     2640

taaaataaaa aaggaagaaa gaaaataatt ttccttgtaa aatcgggcca aaccccaaga     2700

cagctacatt ttcaacaaaa aagcaaacag agaaaaataa atgaacttta acactgtaag     2760

ttcagcattg acagccaact tccagtgtaa gcttttttgt gacaaatccg ggtttaaaaa     2820

tgcttatggg gagaaagctt aaagtttgtt ctaaatgtag tgaaaatgca ctgttgtctt     2880

ggaggtatca tcttgcactc taaccaaaca acaccaaatt aatctggagg tactgatact     2940

aaatttggaa tcccgtcttt aatatgagaa cacaaattac tacaactcag tacctctgtc     3000

ttactctgcc caatttcaat ttagtaatgg caccattatt cttaattccc ttaatgtctg     3060

tccgctgtat ccaattggca cagattttcc ccttcatctt caattactag tagctacccc     3120

catcaattca ccttcctcaa gagtctcaat tgaaaataat ctttgatgat acaatctctg     3180

cttttgccac aggtttgaca ttaactagac gtttctgccc ctgtgctcat taccctccca     3240

aaacaatagt ttttttaatg aattgaaaca caattagatc cattcctgag ttttcatttt     3300

taactattta ctttgtgtca gttggtttct gcatcacaag ggcattctct tacaaaacaa     3360

ctcacaacag aaaaaaaaag tcaagacaaa aaatatatat atatagtatt gacatggaga     3420

tttctttcac ttttttagtc ttagtatgat catctatttt tatatctatg tatatataaa     3480

tcacagattt taacttctta attccaagct cagggttgac acacctttgt aagaaaatgt     3540

tttgtcaacc agctcttctt gttttgtgct gctcaaagaa gggattcctc agtgatcggt     3600

gagcaccaag aatcaagaaa gagaactttt tatgtatcta actgtccatt tattaaaaat     3660

ttgccagggc acacccttct gcatgagtgt gcttcagcct gggtgctcca gactacacca     3720

aactcatggg atgagccatt ggtgtgcagg gctttaccgg tgatggaaac tgtatgtgta     3780

aagaatgtta ttcatgaaaa accattgctt tcatgtaaaa caccttcggc ctaggattcc     3840

tgcctggcac ttggatacat tacctaactc aataggccag tttagagcca cagcctaacc     3900

tgttcaccaa gtaggccaaa gccaggcctt tcgctccccc tgacagagag aagcaaaata     3960

aacccaactg ggggctttat gaatacagtt ggctatccat atgtttctta gtttttatga     4020

tgcatctgga gtagggaaaa gtaatgtttc aagacaccat agtaggccag ttacatttta     4080

attaactcat cgacagtatt gacacgtaaa tggtattttt caatctgttc tcatcaaaat     4140

taaaattagt tattgattta gtcatcacat ttaagtagaa cacatgtggc acaatagtat     4200

taagtatatt tgagcacttt tgcaagacag aaagtattta caagcatcta ttgctacttt     4260

atgcctaatg aaatataaaa tgtaggatga tgagagactt tgtggcattc tttcatttaa     4320

acctttatga aattaaccat ctagttcatc attacatact cctagaaaac catccatttc     4380

actgcccaca ttttggcttc ctaccacaaa ttccacataa gacttctcta tgaaggacca     4440

gtcatttaca ttgctcattt cattctgtgt tcagaagtca gtattgtctt tctccaataa     4500

ttaaggtgca atacaaatta aatcaacctt gattttccag actatttgaa taataacttg     4560

cttttatggc tttaaactcc aggtctttcc tttttaaaat atttctgcat tctcttttat     4620

gaactagatc aggatgcctt gtttttcctg tgctttcacc cccaaaaggt tttgtgcatg     4680

tgtatgaata cacataatat tagtgaatgt gaacccatgt tctatacgca ctaaacacac     4740

agttaatata taaacgcctg cttcatttgt ttcaacacct tcattatcaa tatgattcat     4800

attgatgaga tatagtgatg cataatgagc caggcagaga gctgaaatga tatcagttaa     4860

tgatgtcaca gtgttagcac cctgcatgga tgtggtcaaa atatcattca agttgtactt     4920

cctagttttt atcatcatac tactatgtca tatgattttc agactaattt aacatgagaa     4980

atgttttggc cctaaaggat ttcacttaac ctagttaccc tatttcagta agtattttgg     5040

aattcaaccc tcgaattatt ttttctcatt tcagcatagt gataggggat gcaatgaggc     5100

ttcattattt tttatgacct gcccctcatt tgctctgatg ttccctaaat tctgtaatca     5160

tatcataact tttgttatga atagagagga atgggctcac tgaaacctga cactagaaat     5220

tggtgggtga tgctcataac tgcaaacact tagcttattg aagtgcctct atttacatgt     5280

tctttagtta taatatgtat ttttctaaca gaaatacacg tctgtaattg gtatatatta     5340

tactttgtat gtgtcacaac aaaagctaaa cagaggctaa agtctttagc agagaagaat     5400

gaattacaaa tttaccaata agagctctgt ttatggttct gtattgaagg acaaccatga     5460

caaccttctg tcattttcac gaaggccaag ttggtacttt gattatagcc atcgtagaac     5520

attagcacta gaaatctgtc tcccttacaa tgacttacct agctagcatc aagtaacttg     5580

tatcacctgc tttaaatgta agggatagaa aatactattt tgtctacact gaaaaacatt     5640

attattcatt gataagtagt aataattata aaagtaacat tctttaaagc aaacacattg     5700

aaaatattat tacaggcaga accctgattt ttaatttata ttccctgctg cagacattag     5760

ccttctttaa ttcttttgcc attacataca tgtttcggct acagactgaa cacgaactaa     5820

agtccctaag gaggaaaaaa ccttaacata ttcctgagat gtgattcttt tattacttct     5880

ttttgcaaag ctaattatca aatgatttga ttaaacctag acgcattagg aaatgcaagt     5940

tttacctaaa acttgcagaa atttaaacac atttccattt acttactaac gaacagacct     6000

gatttttatt taaaaacaca atttagcttt gccaacagaa gagtaaagga aaccataact     6060

tataaatttg taatgtgttc ctccttgttg gagacattag ccagtgttta gttttagacc     6120

aacttataca aagagagtat tgatttgtac acattctgga gacttgctat atcatggttt     6180

gctatggcac agactcagct tagcatgggg acattttgaa cttcattcaa agttgagtag     6240

ttactggaac ctttgacatt gccttgtaat gaggtacttc caaaaaaaga cccctaacaa     6300

tggcataata gtgaggtctc tctgtgcata tacataatat atatgcagga taaatgtgtg     6360

caccaatcaa atctaaaatt ttatgtgact gtcaaatgaa tattatttgg gttaagattt     6420

ttcatttctg atttggatag aaaattgcta ttaatcttgt attaaaatag tttttaaaaa     6480

tctaccagtg ccctttctgc attttcttaa ttattgtcat agtctaaatt tcagagccat     6540

ggaatttttt gtgtttgaga catttttaga agcttcaata ttaaaaaaca acaacaaacc     6600

tcgtatatta aaacagtgcc actctcctaa gtacactcag catctgaaat caggaactat     6660

ttgaacttta gaacatttag agcttcccaa atgtgtatgg aaaatactgt agcgctgttc     6720

ttttgtactg atttcttctc agaggataaa tttagtgact tgaaaactga tgtcaatact     6780

ttataaatga ggtcagaaaa taagatcaaa tgtgaaaaga ctaataattt cccaatttag     6840

ccaattgcat tgatttttat acttctgaaa tgtttccatc ctctcaggca tgctaaatat     6900

tgtataacct gctaaagatt tatttcacaa atgcttattg aactcttatt ctctataaac     6960

cctgctctag gggatttatc actggctgtg aaaaaccacc agttgaaaat tattcattcc     7020

ttaatgcagc taatcataat tattacagat aaataatgta tttcaagaat gatcttataa     7080

ataaaggaac ccatacaaac aaaaaaaaaa aaaa                                 7114


<210>  1520
<211>  5154
<212>  DNA
<213>  homo sapiens

<400>  1520
gcaaaatcag ccctccctcc tcccgctcct tcgccgcggc cctcccctcc tcgcgctgct       60

ctcgttcgct tggctcagct cagctcagct cagcgcagct ccgcggccgc caagccgagg      120

cgggcacggt ctccgagtcg cggacgccag ctccgagctc cctctctccg ccgcgcctcc      180

gccaggtcgc gccttcgtcg ggaccacttc gggcaggagt cgcgtggcga aggcctgcgg      240

ccgcggcaca aagttggggg ccgcgaagat gaggctgtcc ccggcgcccc tgaagctgag      300

ccggactccg gcactgctgg ccctggcgct gcccctggcc gcggcgctgg ccttctccga      360

cgagaccctg gacaaagtgc ccaagtcaga gggctactgc agccgtatcc tgcgcgccca      420

gggcacgcgg cgcgagggct acaccgagtt cagcctccgc gtggagggcg accccgactt      480

ctacaagccg ggaaccagct accgcgtaac actttcagct gctcctccct cctacttcag      540

aggattcaca ttaattgccc tcagagagaa cagagagggt gataaggaag aagaccatgc      600

tgggaccttc cagatcatag acgaagaaga aactcagttt atgagcaatt gccctgttgc      660

agtcactgaa agcactccac ggaggaggac ccggatccag gtgttttgga tagcaccacc      720

agcgggaaca ggctgcgtga ttctgaaggc cagcatcgta caaaaacgca ttatttattt      780

tcaagatgag ggctctctga ccaagaaact ttgtgaacaa gattccacat ttgatggggt      840

gactgacaaa cccatcttag actgctgtgc ctgcggaact gccaagtaca gactcacatt      900

ttatgggaat tggtccgaga agacacaccc aaaggattac cctcgtcggg ccaaccactg      960

gtctgcgatc atcggaggat cccactccaa gaattatgta ctgtgggaat atggaggata     1020

tgccagcgaa ggcgtcaaac aagttgcaga attgggctca cccgtgaaaa tggaggaaga     1080

aattcgacaa cagagtgatg aggtcctcac cgtcatcaaa gccaaagccc aatggccagc     1140

ctggcagcct ctcaacgtga gagcagcacc ttcagctgaa ttttccgtgg acagaacgcg     1200

ccatttaatg tccttcctga ccatgatggg ccctagtccc gactggaacg taggcttatc     1260

tgcagaagat ctgtgcacca aggaatgtgg ctgggtccag aaggtggtgc aagacctgat     1320

tccctgggac gctggcaccg acagcggggt gacctatgag tcacccaaca aacccaccat     1380

tccccaggag aaaatccggc ccctgaccag cctggaccat cctcagagtc ctttctatga     1440

cccagagggt gggtccatca ctcaagtagc cagagttgtc atcgagagaa tcgcacggaa     1500

gggtgaacaa tgcaatattg tacctgacaa tgtcgatgat attgtagctg acctggctcc     1560

agaagagaaa gatgaagatg acacccctga aacctgcatc tactccaact ggtccccatg     1620

gtccgcctgc agctcctcca cctgtgacaa aggcaagagg atgcgacagc gcatgctgaa     1680

agcacagctg gacctcagcg tcccctgccc tgacacccag gacttccagc cctgcatggg     1740

ccctggctgc agtgacgaag acggctccac ctgcaccatg tccgagtgga tcacctggtc     1800

gccctgcagc atctcctgcg gcatgggcat gaggtcccgg gagaggtatg tgaagcagtt     1860

cccggaggac ggctccgtgt gcacgctgcc cactgaggaa acggagaagt gcacggtcaa     1920

cgaggagtgc tctcccagca gctgcctgat gaccgagtgg ggcgagtggg acgagtgcag     1980

cgccacctgc ggcatgggca tgaagaagcg gcaccgcatg atcaagatga accccgcaga     2040

tggctccatg tgcaaagccg agacatcaca ggcagagaag tgcatgatgc cagagtgcca     2100

caccatccca tgcttgctgt ccccatggtc cgagtggagt gactgcagcg tgacctgcgg     2160

gaagggcatg cgaacccgac agcggatgct caagtctctg gcagaacttg gagactgcaa     2220

tgaggatctg gagcaggtgg agaagtgcat gctccctgaa tgccccattg actgtgagct     2280

caccgagtgg tcccagtggt cggaatgtaa caagtcatgt gggaaaggcc acgtgattcg     2340

aacccggatg atccaaatgg agcctcagtt tggaggtgca ccctgcccag agactgtgca     2400

gcgaaaaaag tgccgcatcc gaaaatgcct tcgaaatcca tccatccaaa agctacgctg     2460

gagggaggcc cgagagagcc ggcggagtga gcagctgaag gaagagtctg aaggggagca     2520

gttcccaggt tgtaggatgc gcccatggac ggcctggtca gaatgcacca aactgtgcgg     2580

aggtggaatt caggaacgtt acatgactgt aaagaagaga ttcaaaagct cccagtttac     2640

cagctgcaaa gacaagaagg agatcagagc atgcaatgtt catccttgtt agcaagggta     2700

cgagttcccc agggctgcac tctagattcc agagtcacca atggctggat tatttgcttg     2760

tttaagacaa tttaaattgt gtacgctagt tttcattttt gcagtgtggt tcgcccagta     2820

gtcttgtgga tgccagagac atcctttctg aatacttctt gatgggtaca ggctgagtgg     2880

ggcgccctca cctccagcca gcctcttcct gcagaggagt agtgtcagcc accttgtact     2940

aagctgaaac atgtccctct ggagcttcca cctggccagg gaggacggag actttgacct     3000

actccacatg gagaggcaac catgtctgga agtgactatg cctgagtccc agggtgcggc     3060

aggtaggaaa cattcacaga tgaagacagc agattcccca cattctcatc tttggcctgt     3120

tcaatgaaac cattgtttgc ccatctcttc ttagtggaac tttaggtctc ttttcaagtc     3180

tcctcagtca tcaatagttc ctggggaaaa acagagctgg tagacttgaa gaggagcatt     3240

gatgttgggt ggcttttgtt ctttcactga gaaattcgga atacatttgt ctcacccctg     3300

atattggttc ctgatgcccc cccaacaaaa ataaataaat aaattatggc tgctttattt     3360

aaatataagg tagctagttt ttacacctga gataaataat aagcttagag tgtatttttc     3420

ccttgctttt gggggttcag aggagtatgt acaattcttc tgggaagcca gccttctgaa     3480

ctttttggta ctaaatcctt attggaacca agacaaagga agcaaaattg gtctctttag     3540

agaccaattt gcctaaattt taaaatcttc ctacacacat ctagacgttc aagtttgcaa     3600

atcagttttt agcaagaaaa catttttgct atacaaacat tttgctaagt ctgcccaaag     3660

cccccccaat gcattccttc aacaaaatac aatctctgta ctttaaagtt attttagtca     3720

tgaaatttta tatgcagaga gaaaaagtta ccgagacaga aaacaaatct aagggaaagg     3780

aatattatgg gattaagctg agcaagcaat tctggtggaa agtcaaacct gtcagtgctc     3840

cacaccaggg ctgtggtcct cccagacatg cataggaatg gccacaggtt tacactgcct     3900

tcccagcaat tataagcaca ccagattcag ggagactgac caccaaggga tagtgtaaaa     3960

ggacattttc tcagttgggt ccatcagcag tttttcttcc tgcatttatt gttgaaaact     4020

attgtttcat ttcttctttt ataggcctta ttactgctta atccaaatgt gtaccattgg     4080

tgagacacat acaatgctct gaatacacta cgaatttgta ttaaacacat cagaatattt     4140

ccaaatacaa catagtatag tcctgaatat gtacttttaa cacaagagag actattcaat     4200

aaaaactcac tgggtctttc atgtctttaa gctaagtaag tgttcagaag gttctttttt     4260

atattgtcct ccacctccat cattttcaat aaaagatagg gcttttgctc ccttgttctt     4320

ggagggacca ttattacatc tctgaactac ctttgtatcc aacatgtttt aaatccttaa     4380

atgaattgct ttctcccaaa aaaagcacaa tataaagaaa cacaagattt aattattttt     4440

ctacttgggg ggaaaaaagt cctcatgtag aagcacccac ttttgcaatg ttgttctaag     4500

ctatctatct aactctcagc ccatgataaa gttccttaag ctggtgattc ctaatcaagg     4560

acaagccacc ctagtgtctc atgtttgtat ttggtcccag ttgggtacat tttaaaatcc     4620

tgattttgga gacttaaaac caggttaatg gctaagaatg ggtaacatga ctcttgttgg     4680

attgttattt tttgtttgca atggggaatt tataagaagc atcaagtctc tttcttacca     4740

aagtcttgtt aggtggttta tagttctttt ggctaacaaa tcattttgga aataaagatt     4800

ttttactaca aaaatgaaat ttgtttggac ttccacttga gacagtaaag agagtattag     4860

acacccagta aaaactgcca tataaagaag ttgtaattgt ttgttgtgta tgtatttttt     4920

tcaatgccaa accagctgtg atccaattta catccacatt ttaggtccaa cagcaagaag     4980

ttcagagaga gatttcccaa ccagacattg ggtcactcac tggtcacctt gccagtgcat     5040

tttattagaa gggaatctgt tgtagcaaat gggaataaac ctgggtttct atagacccag     5100

aactgaaaaa ataaacatcg tgctgttttt aatttgaaaa aaaaaaaaaa aaaa           5154


<210>  1521
<211>  2473
<212>  DNA
<213>  homo sapiens

<400>  1521
acagatggtg tgggagcgcg ttccccggta ggagggggcg cgagcgagca agcaggcagg       60

cagctgccag gagctcttcc ctgctcgctc acgcctgctc tcagaagctc cgatccagac      120

acacgcgagg cgctgtcctt tcagcaccac aagctcgggc tgaggaggga ggactcctgg      180

ccgtcctcct cctcttcaaa ttggcttgaa tctgctctga ccccccacga gtgcagcaca      240

gtctgggaag aaaggcgtaa ggatggtgaa gctgaacagt aaccccagcg agaagggaac      300

caagccgcct tcagttgagg atggcttcca gaccgtccct ctcatcactc ccttggaggt      360

taatcactta cagctgcctg ctccagaaaa ggtgattgtg aagacaagaa cggaatatca      420

gccggaacag aagaacaaag ggaagttccg ggtgccgaaa atcgctgaat ttacggtcac      480

catccttgtc agcctggccc tagctttcct tgcgtgcatc gtgttcctgg tggtttacaa      540

agccttcacc tatgatcaca gctgcccaga gggattcgtc tataagcaca aacgctgtat      600

cccagcctcc ctggatgctt actactcctc ccaggacccc aattccagaa gccgcttcta      660

cacagtcatc agccactaca gcgtggccaa gcagagcact gcccgggcca tcgggccgtg      720

gctgtcagca gccgctgtca tccatgagcc caagccgccc aagacccagg gccactagag      780

gcctgcccca gccagaatgg ggggcggggt ggagaggagg acccccattg gctaagccaa      840

gctccagtta caagacaaca ctgtactcct gggatatggg ggcgggggcg gggcagggca      900

gggtgggggg aagaacgcac caaaaacgtg gtgtgtgctg gagttgtctg aaccgatatt      960

tctttttgtt ccttggtatt gttgattcgt cgccgagtca ggctcatgta caaaggcatg     1020

tttcgtgttg attgttccca tgtaagatat ttttaaagcc actgcttatt ctttgttagg     1080

aaaatgtaac agcagaaaag gaaagaaaca aagaacatga acaaaaagca ttaaactggc     1140

tccatcagaa gacgttgaag ggcagtgaag agcacagact ctgtgggctt cttagataag     1200

aaaacgtagc ttcagtgggg gctccagggt tgcagagtat gagtgacaca gaccgggact     1260

attccattag cctgtggtct gcagggtagg cccgcaggaa atgaggaatg gccgagctgg     1320

agagaagagc tgattttggc attactaagc ccagaacgca cataacccat agtgaaatgt     1380

gctggcctct ggtgcatttt gcaagatgag cacaaacttt ctgggcctcc atcctaggac     1440

ctgggcagac ccacatggcc tgggctctga atgcccaccc tgcgacggtg ggttctgcat     1500

cagcaaacgc tgaggagtgg gcagattttc tttgtctttt gcttgcattt tctagatcca     1560

cacctggata ctgcccatgt tgacgagaca gcagcagggg gagagggagg gaaggaaggt     1620

gcggctgcaa gaaggaaggc acgggacagg catgtgacac taggccacaa gcgataagca     1680

caggcacctg acttttaagt ttttgtttgt ttgttgtttc ccaaagtgct gataacaata     1740

acaacaacaa taggattcca accaggagcc tcaagtgaca gccaggaaga gacctgaagg     1800

ttggggccac cacaatgcca aatcgtttct aaaggaagct gaaaaatggg actgtctttt     1860

gcccacttcg ttgtgttaaa aggggacatt tgtccaaact ccccaaccga gttctagaag     1920

ctcctgacaa ggaggcagca tccagccttg accaggcctc ccagttccct ggaaccgtat     1980

caggcattcg cctgcctctc acaaatgttt cagggaggcc agttctgcag ggtgtcagct     2040

ccaggaccca cagggccaga accagctggg agaattggtt atttgagatg tggtactgct     2100

tcctcacaag tctcccacag gccatgtaaa gggtattttt ttgtggcttg ctgtgttgct     2160

gagatcatcg tatgcaacag ctgggtaata agactagcat agctcaaact atcctgccaa     2220

acgctctcat ctgatttttc ctcccttctc ccccaacctc caatcaccct gagtcacctg     2280

taaattcatt tgtcattcaa agcggaataa caagttgtcc ctagcaaaac cgctgagcgc     2340

tttataattt tgtggtgtat ttttgtcagt aggtagcaga ggcggaagta ttttttggtg     2400

taattcttga aattttctga caggaaacaa ataaagatag atgtgtctga gaaaaaaaaa     2460

aaaaaaaaaa aaa                                                        2473


<210>  1522
<211>  3666
<212>  DNA
<213>  homo sapiens

<400>  1522
agtggggggg aaggttctag aaaagcggcg gcagcggctc tagcggcagt agcagcagcg       60

ccgggtcccg tgcggaggtg ctcctcgcag agttgtttct cgagcagcgg cagttctcac      120

tacagcgcca ggacgagtcc ggttcgtgtt cgtccgcgga gatctctctc atctcgctcg      180

gctgcgggaa atcgggctga agcgactgag tccgcgatgg agagagaaaa ggaacagttc      240

cgtaagctct ttattggtgg cttaagcttt gaaaccacag aagaaagttt gaggaactac      300

tacgaacaat ggggaaagct tacagactgt gtggtaatga gggatcctgc aagcaaaaga      360

tcaagaggat ttggttttgt aactttttca tccatggctg aggttgatgc tgccatggct      420

gcaagacctc attcaattga tgggagagta gttgagccaa aacgtgctgt agcaagagag      480

gaatctggaa aaccaggggc tcatgtaact gtgaagaagc tgtttgttgg cggaattaaa      540

gaagatactg aggaacatca ccttagagat tactttgagg aatatggaaa aattgatacc      600

attgagataa ttactgatag gcagtctgga aagaaaagag gctttggctt tgttactttt      660

gatgaccatg atcctgtgga taaaatcgta ttgcagaaat accataccat caatggtcat      720

aatgcagaag taagaaaggc tttgtctaga caagaaatgc aggaagttca gagttctagg      780

agtggaagag gaggcaactt tggctttggg gattcacgtg gtggcggtgg aaatttcgga      840

ccaggaccag gaagtaactt tagaggagga tctgatggat atggcagtgg acgtggattt      900

ggggatggct ataatgggta tggaggagga cctggaggtg gcaattttgg aggtagcccc      960

ggttatggag gaggaagagg aggatatggt ggtggaggac ctggatatgg caaccagggt     1020

gggggctacg gaggtggtta tgacaactat ggaggaggaa attatggaag tggaaattac     1080

aatgattttg gaaattataa ccagcaacct tctaactacg gtccaatgaa gagtggaaac     1140

tttggtggta gcaggaacat ggggggacca tatggtggag gaaactatgg tccaggaggc     1200

agtggaggaa gtgggggtta tggtgggagg agccgatact gagcttcttc ctatttgcca     1260

tgggcttcac tgtataaata ggagaggatg agagcccaga ggtaacagaa cagcttcagg     1320

ttatcgaaat aacaatgtta aggaaactct tatctcagtc atgcataaat atgcagtgat     1380

atggcagaag acaccagagc agatgcagag agccattttg tgaatggatt ggattattta     1440

ataacattac cttactgtgg aggaaggatt gtaaaaaaaa atgcctttga gacagtttct     1500

tagcttttta attgttgttt ctttctagtg gtctttgtaa gagtgtagaa gcattccttc     1560

tttgataatg ttaaatttgt aagtttcagg tgacatgtga aacctttttt aagatttttc     1620

tcaaagtttt gaaaagctat tagccaggat catggtgtaa taagacataa cgtttttcct     1680

ttaaaaaaat ttaagtgcgt gtgtagagtt aagaagctgt tgtacattta tgatttaata     1740

aaataattct aaaggaaatt gtgtaattat agacttttta ttttaaataa gttaaggagt     1800

gggtagtata attaaggtcc gttgcaaagc tgttgttata tttgtataag ataaatgctg     1860

gtcagatgta agtgtgttgt ctgcaattca tcaggattaa attatgtaga taacttaagg     1920

gatatctctg caaggagaaa caccttttta gatcttttag atgctgcttc ttcaatgcaa     1980

ggaaaggaaa taaccccagc gaggtactct tcagggacac aggtctagta caagagaact     2040

cttgacggct actaagttca gccagtctta aaaaactgtg ctgtttctac aaaactttaa     2100

ctacagtagt ttataaggat gccaacgaaa gctgagggtg tagagcaaaa tagttctaag     2160

cttcagttaa acttctttag gtaagatctt atttactttt cctttcttaa ttttcctccc     2220

taaaagataa actaatactc ttaaatggtc tttcagtata gtggttctta cgtagtttaa     2280

catagctata aattgagttt aacaatttat aaactcaaga gaataatttt tataaaccct     2340

gttttccaat ctgtcattta cttaaattat tttggttgtt tttccctttt tttccttctt     2400

ttcccacccc ctccccctcc atgtgaagat ttgggtgctt aacatatcat ttttttccct     2460

gccggaattt tagcattgat atgaaccatg gacaagtata ttctgctgcc acaaagactg     2520

taaagtgctt catttcaaca gctgaggcaa gccaagtgat cattaataaa gcttttcttg     2580

gttccttcag tggtgttggt agtaaaatgg taggtaaaag ttaggctgca agttcaataa     2640

atcatgagat ttcccatcgt tacacccttg tgtattcaca tttcttggat caaacatttt     2700

gagtgaacta ggggttttta ttaaagacat ttgttgtatt tatggttgta actgtacatg     2760

cttatcagga tgagactgaa agaaggtagg gcaaaaatgg ttgaatctat tttcagatag     2820

tagttcatac ttgagtgaag tgtcttgtct gcattatgaa gcctggtatg tatccagtac     2880

taaataggtg ggttaaatgt ggtaattcta gttcagtgtc ttaccctgaa gagaaagttg     2940

taggttggct gttgaaattc attccttaga tatgatcagt ttgattgccc ggctttattg     3000

cctttacagg aatgtgatac tcagggctta ctctatacac caatgagtct tctttgatcc     3060

taagaccacc actgaagttg tttaggttct tttggacaaa catgataaac ttcttcagat     3120

actttttttt tcctttggca ggaaggtgtc ttgctgcagg taactaatga agaagtggtc     3180

aaccacagag tcttcaagaa ataagaaatt ctgtaccatc tgaaagtagt tcttgttggt     3240

gccttcattt aaaaagcact ctttaaaata aaagggaaat gttttctgat aaaacaaaca     3300

tttagttgag gttcttgata taaaacaatt acaaaatgag tgttgtttgt aaaacagtaa     3360

catcaaattg gctagagaga taaatgtatc atgttttaaa ttaggttttg tgagtagaca     3420

gattacaatt ctattttaaa tataaagttt ataaaataaa tactttttgt atccaaatac     3480

ttggtgtaat gtttacacat aaaatgtgtg aatcttgttc tataaatatt tggttgtcta     3540

aaagatcacc atcccctaaa tttttaaaag cagtttcaca aagctatgca tattttaata     3600

ttaacaggta aatgagaaga gcattgtgga cattattggc tgtccccaat aaaatgctgt     3660

tcatta                                                                3666


<210>  1523
<211>  3552
<212>  DNA
<213>  homo sapiens

<400>  1523
ggcggcggcg gcggcggcag aagcggcagc gctcgccatt gccgctggtg gcaggaggct       60

gcgaggagcc ggcgcggtcg cagtctccac ggcgcaggcc cacggtagcg cagccgctct      120

gagaacttca tggaggaaca cggagtgacc caaaccgaac atatggctac catagaagca      180

catgcagtgg cccagcaagt gcagcaggtc catgtggcta cttacaccga gcatagtatg      240

ctgagtgctg atgaagactc gccttcttct cccgaggaca cctcttacga tgactcagat      300

atactcaact ccacagcagc tgatgaggtg acagctcatc tggcagctgc aggtcctgtg      360

ggaatggccg ctgctgctgc tgtggcaaca ggaaagaaac ggaaacggcc tcatgtattt      420

gagtctaatc catctatccg gaagaggcaa caaacacgtt tgcttcggaa acttcgagcc      480

acgttagatg aatatactac tcgtgtggga cagcaagcta ttgtcctctg tatctcaccc      540

tccaaaccta accctgtctt taaagtgttt ggtgcagcac ctttggagaa tgtggtgcgt      600

aagtacaaga gcatgatcct ggaagacctg gagtctgctc tggcagaaca cgcccctgcg      660

ccacaggagg ttaactcaga actgccgcct ctcaccatcg acggaattcc agtctctgtg      720

gacaaaatga cccaggccca gcttcgggca tttatcccag agatgctcaa gtactctaca      780

ggtcggggaa aaccaggctg ggggaaagaa agctgcaagc ccatctggtg gcctgaagat      840

atcccctggg caaatgtccg gagtgatgtc cgcacagaag agcaaaagca gagggtttca      900

tggacccagg cactacggac catagttaaa aactgttata aacagcatgg gcgggaagac      960

cttttgtatg cctttgaaga tcagcaaacg caaacacagg ccacagccac acatagtata     1020

gctcatcttg taccatcaca gactgtagtc cagactttta gtaaccctga tggcactgtc     1080

tcacttatcc aggttggtac gggggcaaca gtagccacat tggctgatgc ttcagaattg     1140

ccaaccacgg tcaccgttgc ccaagtgaat tattctgccg tggctgatgg agaggtggaa     1200

caaaattggg ccacgttaca gggaggtgag atgaccatcc agacgacgca agcatcagag     1260

gccacccagg cggtggcatc gttggcagag gccgcagtgg cagcttctca ggagatgcag     1320

cagggagcta cagtcactat ggcgcttaac agcgaagctg ccgcccatgc tgtcgccacc     1380

ctggctgagg ccaccttaca aggtggggga cagatcgtct tgtctgggga aaccgcagca     1440

gccgtcggag cacttactgg agtccaagat gctaatggcc tggtccagat ccctgtgagc     1500

atgtaccaga ctgtggtgac cagcctcgcc cagggcaacg gaccagtgca ggtggccatg     1560

gcccctgtga ccaccaggat atcagacagc gcagtcacca tggacggcca agctgtggag     1620

gtggtgacat tggaacagtg acatacagcc atattatggc atcgttttct agtctacttc     1680

aaaatttttt acacgtttgc agaggtgcaa tcaaatggaa ttaagtctct cgactttgga     1740

aggaaagttt tgttaacctt ttttttttta aaaggaagaa agcggatttt ggaattgcat     1800

tttttaaagc accactcttg attttctggg attggtgaag aaactgcatt gtcaatttca     1860

ctgtcccaaa aaagccaaat tgtggcagga cttctttctg cggaaatgtg tgtgtatact     1920

tatgtgtgtg tatgtgtgag tgtgaatata tgtatatgtg tacatatgga catacacatt     1980

tacatatata taaagtatat atatacatat atatatatat atatgtatga aacccgcatg     2040

gaattatctg tatgaaatca aggtgcgctg tggaaacaat aattcaccca gtttagtggg     2100

tggtagggta cgtggccaga cacagtcacc cagtttttgt tcataccagg gtcatgcgtt     2160

gagctactga caaactcagg cggaggtgac catgcccttc accaaagctg cctcccagtg     2220

gccacacaga actctccctg ctggactcac ctgaggaaag aggctccagc atggggtggg     2280

tcagagatgt gcttgcaagg tccagggact gcgtggtctg ccagctgaga tgctcctcgg     2340

gctggcccag gtgctgacct tgccacaggc agatgaatgt cttgaaagct cccgggcctc     2400

agcctcccat ctcctctcct tcccaggaat ccttgatctc atgactatta aaatgttgct     2460

ctggttttaa ggtcagtcct gaattgctcg tatatatgaa ctgaaggtaa ccgaagtatt     2520

aggggtttga ggagtgcgtg cgtgtaagtg tgcttgtgtg tgtgcgtgca tggtggggga     2580

gaggatggga agggggcggg ggcagtggaa gggaaaggaa ggaaagaaaa atcgtcctag     2640

accaggatac acccgtggga gcaattttct ctactgtctg tagcttcaca gaggaggcgc     2700

tggaatgaac aagaagagac atctggtctg tggccacagc accctgaacg cccctgatct     2760

tgtgtgatct tggaagctaa gcttggttgg gcccggtcag tacgcggaag ggaagaaggg     2820

acacctggcc atagaaaaca gctgagggtg tttgctgtgt tcctggatca ggccctgctt     2880

cagaagggac tcctggaggc ccatgttcct tgatgcaacc tcgtggccca ggccgggagc     2940

agcttgcctc ctcagaggtg ttgactatct gggtgttctt ggtaaccgtt aactctgtct     3000

ttctcagctg caagccctga gtctccagta gctgaattca cctgactttt caacaggcca     3060

aatctctgaa ccttgagtac agggacagct cctcctccct cctcccagct ctccccatgt     3120

gtgtgatggt gtatttaatg tgttttttta atgcgacatt aaaagattct ccacgtcttg     3180

ctcaaccttt gagagaagtt tcagattctt gtatttgctt gttttatata aaactatcta     3240

atgttcttta tatgttcttt tctgtacgta atggggggag gggagggaaa tttacatata     3300

aatagtccta gttctacaat ttgttatttt tttaattatt attttttatc gtcattgtga     3360

agttgtccag ggactttaaa gtccatgttc ctttgtggtg aaataacctc caaatagttt     3420

gagaagttgc caagacgaag aaaaaagcaa aaccccagta gcagagcatg gattctgtgt     3480

tgtttcccat tctgtctttg actgcctcat tcaataaata gttaaaaatg tggcaacagg     3540

aaaaaaaaaa aa                                                         3552


<210>  1524
<211>  3552
<212>  DNA
<213>  homo sapiens

<400>  1524
ggcggcggcg gcggcggcag aagcggcagc gctcgccatt gccgctggtg gcaggaggct       60

gcgaggagcc ggcgcggtcg cagtctccac ggcgcaggcc cacggtagcg cagccgctct      120

gagaacttca tggaggaaca cggagtgacc caaaccgaac atatggctac catagaagca      180

catgcagtgg cccagcaagt gcagcaggtc catgtggcta cttacaccga gcatagtatg      240

ctgagtgctg atgaagactc gccttcttct cccgaggaca cctcttacga tgactcagat      300

atactcaact ccacagcagc tgatgaggtg acagctcatc tggcagctgc aggtcctgtg      360

ggaatggccg ctgctgctgc tgtggcaaca ggaaagaaac ggaaacggcc tcatgtattt      420

gagtctaatc catctatccg gaagaggcaa caaacacgtt tgcttcggaa acttcgagcc      480

acgttagatg aatatactac tcgtgtggga cagcaagcta ttgtcctctg tatctcaccc      540

tccaaaccta accctgtctt taaagtgttt ggtgcagcac ctttggagaa tgtggtgcgt      600

aagtacaaga gcatgatcct ggaagacctg gagtctgctc tggcagaaca cgcccctgcg      660

ccacaggagg ttaactcaga actgccgcct ctcaccatcg acggaattcc agtctctgtg      720

gacaaaatga cccaggccca gcttcgggca tttatcccag agatgctcaa gtactctaca      780

ggtcggggaa aaccaggctg ggggaaagaa agctgcaagc ccatctggtg gcctgaagat      840

atcccctggg caaatgtccg gagtgatgtc cgcacagaag agcaaaagca gagggtttca      900

tggacccagg cactacggac catagttaaa aactgttata aacagcatgg gcgggaagac      960

cttttgtatg cctttgaaga tcagcaaacg caaacacagg ccacagccac acatagtata     1020

gctcatcttg taccatcaca gactgtagtc cagactttta gtaaccctga tggcactgtc     1080

tcacttatcc aggttggtac gggggcaaca gtagccacat tggctgatgc ttcagaattg     1140

ccaaccacgg tcaccgttgc ccaagtgaat tattctgccg tggctgatgg agaggtggaa     1200

caaaattggg ccacgttaca gggaggtgag atgaccatcc agacgacgca agcatcagag     1260

gccacccagg cggtggcatc gttggcagag gccgcagtgg cagcttctca ggagatgcag     1320

cagggagcta cagtcactat ggcgcttaac agcgaagctg ccgcccatgc tgtcgccacc     1380

ctggctgagg ccaccttaca aggtggggga cagatcgtct tgtctgggga aaccgcagca     1440

gccgtcggag cacttactgg agtccaagat gctaatggcc tggtccagat ccctgtgagc     1500

atgtaccaga ctgtggtgac cagcctcgcc cagggcaacg gaccagtgca ggtggccatg     1560

gcccctgtga ccaccaggat atcagacagc gcagtcacca tggacggcca agctgtggag     1620

gtggtgacat tggaacagtg acatacagcc atattatggc atcgttttct agtctacttc     1680

aaaatttttt acacgtttgc agaggtgcaa tcaaatggaa ttaagtctct cgactttgga     1740

aggaaagttt tgttaacctt ttttttttta aaaggaagaa agcggatttt ggaattgcat     1800

tttttaaagc accactcttg attttctggg attggtgaag aaactgcatt gtcaatttca     1860

ctgtcccaaa aaagccaaat tgtggcagga cttctttctg cggaaatgtg tgtgtatact     1920

tatgtgtgtg tatgtgtgag tgtgaatata tgtatatgtg tacatatgga catacacatt     1980

tacatatata taaagtatat atatacatat atatatatat atatgtatga aacccgcatg     2040

gaattatctg tatgaaatca aggtgcgctg tggaaacaat aattcaccca gtttagtggg     2100

tggtagggta cgtggccaga cacagtcacc cagtttttgt tcataccagg gtcatgcgtt     2160

gagctactga caaactcagg cggaggtgac catgcccttc accaaagctg cctcccagtg     2220

gccacacaga actctccctg ctggactcac ctgaggaaag aggctccagc atggggtggg     2280

tcagagatgt gcttgcaagg tccagggact gcgtggtctg ccagctgaga tgctcctcgg     2340

gctggcccag gtgctgacct tgccacaggc agatgaatgt cttgaaagct cccgggcctc     2400

agcctcccat ctcctctcct tcccaggaat ccttgatctc atgactatta aaatgttgct     2460

ctggttttaa ggtcagtcct gaattgctcg tatatatgaa ctgaaggtaa ccgaagtatt     2520

aggggtttga ggagtgcgtg cgtgtaagtg tgcttgtgtg tgtgcgtgca tggtggggga     2580

gaggatggga agggggcggg ggcagtggaa gggaaaggaa ggaaagaaaa atcgtcctag     2640

accaggatac acccgtggga gcaattttct ctactgtctg tagcttcaca gaggaggcgc     2700

tggaatgaac aagaagagac atctggtctg tggccacagc accctgaacg cccctgatct     2760

tgtgtgatct tggaagctaa gcttggttgg gcccggtcag tacgcggaag ggaagaaggg     2820

acacctggcc atagaaaaca gctgagggtg tttgctgtgt tcctggatca ggccctgctt     2880

cagaagggac tcctggaggc ccatgttcct tgatgcaacc tcgtggccca ggccgggagc     2940

agcttgcctc ctcagaggtg ttgactatct gggtgttctt ggtaaccgtt aactctgtct     3000

ttctcagctg caagccctga gtctccagta gctgaattca cctgactttt caacaggcca     3060

aatctctgaa ccttgagtac agggacagct cctcctccct cctcccagct ctccccatgt     3120

gtgtgatggt gtatttaatg tgttttttta atgcgacatt aaaagattct ccacgtcttg     3180

ctcaaccttt gagagaagtt tcagattctt gtatttgctt gttttatata aaactatcta     3240

atgttcttta tatgttcttt tctgtacgta atggggggag gggagggaaa tttacatata     3300

aatagtccta gttctacaat ttgttatttt tttaattatt attttttatc gtcattgtga     3360

agttgtccag ggactttaaa gtccatgttc ctttgtggtg aaataacctc caaatagttt     3420

gagaagttgc caagacgaag aaaaaagcaa aaccccagta gcagagcatg gattctgtgt     3480

tgtttcccat tctgtctttg actgcctcat tcaataaata gttaaaaatg tggcaacagg     3540

aaaaaaaaaa aa                                                         3552


<210>  1525
<211>  2483
<212>  DNA
<213>  homo sapiens

<400>  1525
gcgcgctctg ctcggctgca ggctcaggaa gcggcgcggc ggcacgtgct gggccagagc       60

cccgcgccct gcgtccagcc gccgggtgtg tgcgcccgcg tagcccagcg tcgcgcctcg      120

gcgcccccac gcgcccacgc agcggcgcgg ggacccgggc gggggcagag ggagggcccg      180

gcccagggag gagaaggggc cggtcctccc ggcgcaggca gcagccgcgg cagcccagga      240

ggcggaggca gcggcaacgg cagagacagc aacgtgcccg ccgcagtcag cccggcctcg      300

tcggacccgc accggcccgc ccgcccgccc gcaccgcgtc ggggcgccct ctccactgcg      360

cgcggtacaa ggaaatggta gaactagtga tctcacccag cctcactgta aacagcgatt      420

gtctggataa actgaagttt aaccgtgctg acgctgctgt gtggactctg agtgacagac      480

aaggcatcac caaatcggcc cccctgagag tgtcccagct cttctccaga tcttgcccac      540

gtgtcctccc ccgccagcct tccacagcca tggcagccta cggccagacg cagtacagtg      600

cggggatcca gcaggctacc ccctatacag cttacccacc tccagcacaa gcctatggaa      660

tcccttccta cagcatcaag acagaagaca gcttgaacca ttcccctggc cagagtggat      720

tcctcagcta tggctccagc ttcagcacct cacccactgg acagagccca tacacctacc      780

agatgcacgg cacaacaggg ttctatcaag gaggaaatgg actgggcaac gcagccggtt      840

tcgggagtgt gcaccaggac tatccttcct accccggctt cccccagagc cagtaccccc      900

agtattacgg ctcatcctac aaccctccct acgtcccggc cagcagcatc tgcccttcgc      960

ccctctccac gtccacctac gtcctccagg aggcatctca caacgtcccc aaccagagtt     1020

ccgagtcact tgctggtgaa tacaacacac acaatggacc ttccacacca gcgaaagagg     1080

gagacacaga caggccgcac cgggcctccg acgggaagct ccgaggccgg tctaagagga     1140

gcagtgaccc gtccccggca ggggacaatg agattgagcg tgtgttcgtg tgggacttgg     1200

atgagacaat aattattttt cactccttac tcacggggac atttgcatcc agatacggga     1260

aggacaccac gacgtccgtg cgcattggcc ttatgatgga agagatgatc ttcaaccttg     1320

cagatacaca tctgttcttc aatgacctgg aggattgtga ccagatccac gttgatgacg     1380

tctcatcaga tgacaatggc caagatttaa gcacatacaa cttctccgct gacggcttcc     1440

acagttcggc cccaggagcc aacctgtgcc tgggctctgg cgtgcacggc ggcgtggact     1500

ggatgaggaa gctggccttc cgctaccggc gggtgaagga gatgtacaat acctacaaga     1560

acaacgttgg tgggaaggag agctgcttcg agaggataat gcagagattc ggcagaaaag     1620

ctgtctacgt ggtgatcggt gatggtgtgg aagaggagca aggagcgaaa aagcacaaca     1680

tgcctttctg gcggatatcc tgccacgcag acctggaggc actgaggcac gccctggagc     1740

tggagtattt atagcaggat cagcagcatc tccacctgcc atctcaccct cagaccccct     1800

cgccttcccc acctccccac cgagaactcc agagacccag atgttggaca ccaggaaggg     1860

gccccacagc cgagacgacg tgtccagtga ccatctcaga agccgtccat cagtccaaat     1920

gggggttctg agaaggaaag tacccaacat tggcttcgga gtatttgact ttggggaaaa     1980

gggctggctc ggagtctaga ctcttctgta agactcacag aacaaaagca aggaattgct     2040

gatttggggg gtgcctggtg atgaggaggg gatgggtttg tcttgtcttc tttttaattt     2100

atggactagt ctcattactc cggaattatg ctcttgtacc tgtgtggctg ggtttcttag     2160

tcgttggttt ggtttggttt tttgaactgg tatgtggggt ggttcacagt tctaatgtaa     2220

gcactctatt ctccaagttg tgctttgtgg ggacaatcat tctttgaaca ttagagagga     2280

aggcagttca agctgttgaa aagactattg cttatttttg tttttaaaga cctacttgac     2340

gtcatgtgga cagtgcacgt gccttacgct acatcttgtt ttctaggaag agggggatgc     2400

tgggaaggaa tgggtgcttt gtgatggata aaaggcatta aataaaacca cgtttacatt     2460

ttgaaaaaaa aaaaaaaaaa aaa                                             2483


<210>  1526
<211>  2591
<212>  DNA
<213>  homo sapiens

<400>  1526
ggcggcgctt gattgggctg ggggggccaa ataaaagcga tggcgattgg gctgccgcgt       60

ttggcgctcg gtccggtcgc gtccgacacc cggtgggact cagaaggcag tggagccccg      120

gcggcggcgg cggcggcgcg cgggggcgac gcgcgggaac aacgcgagtc ggcgcgcggg      180

acgaagaata atcatgggcc agactgggaa gaaatctgag aagggaccag tttgttggcg      240

gaagcgtgta aaatcagagt acatgcgact gagacagctc aagaggttca gacgagctga      300

tgaagtaaag agtatgttta gttccaatcg tcagaaaatt ttggaaagaa cggaaatctt      360

aaaccaagaa tggaaacagc gaaggataca gcctgtgcac atcctgactt ctgtgagctc      420

attgcgcggg actagggagg tggaagatga aactgtttta cataacattc cttatatggg      480

agatgaagtt ttagatcagg atggtacttt cattgaagaa ctaataaaaa attatgatgg      540

gaaagtacac ggggatagag aatgtgggtt tataaatgat gaaatttttg tggagttggt      600

gaatgccctt ggtcaatata atgatgatga cgatgatgat gatggagacg atcctgaaga      660

aagagaagaa aagcagaaag atctggagga tcaccgagat gataaagaaa gccgcccacc      720

tcggaaattt ccttctgata aaatttttga agccatttcc tcaatgtttc cagataaggg      780

cacagcagaa gaactaaagg aaaaatataa agaactcacc gaacagcagc tcccaggcgc      840

acttcctcct gaatgtaccc ccaacataga tggaccaaat gctaaatctg ttcagagaga      900

gcaaagctta cactcctttc atacgctttt ctgtaggcga tgttttaaat atgactgctt      960

cctacatcct tttcatgcaa cacccaacac ttataagcgg aagaacacag aaacagctct     1020

agacaacaaa ccttgtggac cacagtgtta ccagcatttg gagggagcaa aggagtttgc     1080

tgctgctctc accgctgagc ggataaagac cccaccaaaa cgtccaggag gccgcagaag     1140

aggacggctt cccaataaca gtagcaggcc cagcaccccc accattaatg tgctggaatc     1200

aaaggataca gacagtgata gggaagcagg gactgaaacg gggggagaga acaatgataa     1260

agaagaagaa gagaagaaag atgaaacttc gagctcctct gaagcaaatt ctcggtgtca     1320

aacaccaata aagatgaagc caaatattga acctcctgag aatgtggagt ggagtggtgc     1380

tgaagcctca atgtttagag tcctcattgg cacttactat gacaatttct gtgccattgc     1440

taggttaatt gggaccaaaa catgtagaca ggtgtatgag tttagagtca aagaatctag     1500

catcatagct ccagctcccg ctgaggatgt ggatactcct ccaaggaaaa agaagaggaa     1560

acaccggttg tgggctgcac actgcagaaa gatacagctg aaaaaggacg gctcctctaa     1620

ccatgtttac aactatcaac cctgtgatca tccacggcag ccttgtgaca gttcgtgccc     1680

ttgtgtgata gcacaaaatt tttgtgaaaa gttttgtcaa tgtagttcag agtgtcaaaa     1740

ccgctttccg ggatgccgct gcaaagcaca gtgcaacacc aagcagtgcc cgtgctacct     1800

ggctgtccga gagtgtgacc ctgacctctg tcttacttgt ggagccgctg accattggga     1860

cagtaaaaat gtgtcctgca agaactgcag tattcagcgg ggctccaaaa agcatctatt     1920

gctggcacca tctgacgtgg caggctgggg gatttttatc aaagatcctg tgcagaaaaa     1980

tgaattcatc tcagaatact gtggagagat tatttctcaa gatgaagctg acagaagagg     2040

gaaagtgtat gataaataca tgtgcagctt tctgttcaac ttgaacaatg attttgtggt     2100

ggatgcaacc cgcaagggta acaaaattcg ttttgcaaat cattcggtaa atccaaactg     2160

ctatgcaaaa gttatgatgg ttaacggtga tcacaggata ggtatttttg ccaagagagc     2220

catccagact ggcgaagagc tgttttttga ttacagatac agccaggctg atgccctgaa     2280

gtatgtcggc atcgaaagag aaatggaaat cccttgacat ctgctacctc ctcccccctc     2340

ctctgaaaca gctgccttag cttcaggaac ctcgagtact gtgggcaatt tagaaaaaga     2400

acatgcagtt tgaaattctg aatttgcaaa gtactgtaag aataatttat agtaatgagt     2460

ttaaaaatca actttttatt gccttctcac cagctgcaaa gtgttttgta ccagtgaatt     2520

tttgcaataa tgcagtatgg tacatttttc aactttgaat aaagaatact tgaacttgtc     2580

cttgttgaat c                                                          2591


<210>  1527
<211>  3944
<212>  DNA
<213>  homo sapiens

<400>  1527
ctccttcctg caagaagcgt tgcccgttgg ctagctgctc ggtggggatc tgcctgccct       60

gggggcgccg cccgcgctcc ccgcggtgct ctcgctcctg ggctgcgcca gtccgaggcg      120

gtgccggctc ctttgcctcc ccgagtcgca gatgctgcgg gcgcctccgg gaaaagatct      180

gggcggcgcg ctcgctcgat ggacacagga agatccagaa gctagtggca catctagcaa      240

cagagccaga tcagaaccca gatgctaaac tcctggtgga ctgcagagga gagggattca      300

gtcttctcct gatgtcgatt gcgatttctg ctgggagctc aagacgggcg agctgcccga      360

gatctcttcg agatacccca ggggaggagg agatgggcag gatttagtag gacaactcgg      420

ttactaatga cttggcggct ggctgcgacc ccccgggaaa tcaggtgcaa gcatgtttgc      480

ctgtaggtac ctgagttgac accgaaggtg cctaaagatg ctgagcggcg tttggttcct      540

cagtgtgtta accgtggccg ggatcttaca gacagagagt cgcaaaactg ccaaagacat      600

ttgcaagatc cgctgtctgt gcgaagaaaa ggaaaacgta ctgaatatca actgtgagaa      660

caaaggattt acaacagtta gcctgctcca gcccccccag tatcgaatct atcagctttt      720

tctcaatgga aacctcttga caagactgta tccaaacgaa tttgtcaatt actccaacgc      780

ggtgactctt cacctaggta acaacgggtt acaggagatc cgaacggggg cattcagtgg      840

cctgaaaact ctcaaaagac tgcatctcaa caacaacaag cttgagatat tgagggagga      900

caccttccta ggcctggaga gcctggagta tctccaggcc gactacaatt acatcagtgc      960

catcgaggct ggggcattca gcaaacttaa caagctcaaa gtgctcatcc tgaatgacaa     1020

ccttctgctt tcactgccca gcaatgtgtt ccgctttgtc ctgctgaccc acttagacct     1080

cagggggaat aggctaaaag taatgccttt tgctggcgtc cttgaacata ttggagggat     1140

catggagatt cagctggagg aaaatccatg gaattgcact tgtgacttac ttcctctcaa     1200

ggcctggcta gacaccataa ctgtttttgt gggagagatt gtctgtgaga ctccctttag     1260

gttgcatggg aaagacgtga cccagctgac caggcaagac ctctgtccca gaaaaagtgc     1320

cagtgattcc agtcagaggg gcagccatgc tgacacccac gtccaaaggc tgtcacctac     1380

aatgaatcct gctctcaacc caaccagggc tccgaaagcc agccggccgc ccaaaatgag     1440

aaatcgtcca actcctcgag tgactgtgtc aaaggacagg caaagttttg gacccatcat     1500

ggtgtaccag accaagtctc ctgtgcctct cacctgtccc agcagctgtg tctgcacctc     1560

tcagagctca gacaatggtc tgaatgtaaa ctgccaagaa aggaagttca ctaatatctc     1620

tgacctgcag cccaaaccga ccagtccaaa gaaactctac ctaacaggga actatcttca     1680

aactgtctat aagaatgacc tcttagaata cagttctttg gacttactgc acttaggaaa     1740

caacaggatt gcagtcattc aggaaggtgc ctttacaaac ctgaccagtt tacgcagact     1800

ttatctgaat ggcaattacc ttgaagtgct gtacccttct atgtttgatg gactgcagag     1860

cttgcaatat ctctatttag agtataatgt cattaaggaa attaagcctc tgacctttga     1920

tgctttgatt aacctacagc tactgtttct gaacaacaac cttcttcggt ccttacctga     1980

taatatattt ggggggacgg ccctaaccag gctgaatctg agaaacaacc atttttctca     2040

cctgcccgtg aaaggggttc tggatcagct cccggctttc atccagatag atctgcagga     2100

gaacccctgg gactgtacct gtgacatcat ggggctgaaa gactggacag aacatgccaa     2160

ttcccctgtc atcattaatg aggtgacttg cgaatctcct gctaagcatg caggggagat     2220

actaaaattt ctggggaggg aggctatctg tccagacagc ccaaacttgt cagatggaac     2280

cgtcttgtca atgaatcaca atacagacac acctcggtcg cttagtgtgt ctcctagttc     2340

ctatcctgaa ctacacactg aagttccact gtctgtctta attctgggat tgcttgttgt     2400

tttcatctta tctgtctgtt ttggggctgg tttattcgtc tttgtcttga aacgccgaaa     2460

gggagtgccg agcgttccca ggaataccaa caacttagac gtaagctcct ttcaattaca     2520

gtatgggtct tacaacactg agactcacga taaaacagac ggccatgtct acaactatat     2580

ccccccacct gtgggtcaga tgtgccaaaa ccccatctac atgcagaagg aaggagaccc     2640

agtagcctat taccgaaacc tgcaagagtt cagctatagc aacctggagg agaaaaaaga     2700

agagccagcc acacctgctt acacaataag tgccactgag ctgctagaaa agcaggccac     2760

accaagagag cctgagctgc tgtatcaaaa tattgctgag cgagtcaagg aacttcccag     2820

cgcaggccta gtccactata acttttgtac cttacctaaa aggcagtttg ccccttccta     2880

tgaatctcga cgccaaaacc aagacagaat caataaaacc gttttatatg gaactcccag     2940

gaaatgcttt gtggggcagt caaaacccaa ccacccttta ctgcaagcta agccgcaatc     3000

agaaccggac tacctcgaag ttctggaaaa acaaactgca atcagtcagc tgtgaaggga     3060

aatcatttac aaccctaagg catcagagga tgctgctccg aactgttgga aacaaggaca     3120

ttagcttttg tgtttgtttt tgttctccct ttcccagtgt taatggggga ctttgaaaat     3180

gtttgggaga taggatgaag tcatgatttt gcttttgcaa gttttccttt aaattatttc     3240

tctctcgctc tcctcccctc cttttttttt tttttttttt tttctttttc ccttctcttc     3300

ttaggaacca tcagtggaca tgaatgtttc tacaatgcat ttcttcatag attttgttta     3360

tggttttgtt tcttttttct tctttgtttt tcagtgtggg agtgggaaga ggagattata     3420

gtgactgaag aaagaatagg caaacttttc aaatgaaaat ggatatttag tgtattttgt     3480

agaagatctc caaagatctt ttgtgactac aacttctttt gtaaataatg atatatggta     3540

tttccatcgt cagttaccga gtatagccac tgggtatcac tactttgtgt taaagtgcct     3600

tcgcacttta agtacattac ttaaatgttg cttttagctt tgataaattg aaaatatttt     3660

aatgtgttgt atttttgaaa ttgaaaacac tgtaaaatag attgatgtgt cagctatatt     3720

aagtcaacgt acagtttgct tgagttatag aaaccagcct gtcatcaaat gattctagtt     3780

ctaggacttt gtaggcttaa ctataaaata tttcctttcc tctgggttta agtgatttta     3840

tttaagtcaa ctaaggggat ttaacagtgg actagaggta ataagccacc tcagtcagga     3900

ttaataattc attaataaaa tatatttaac ccaaaaaaaa aaaa                      3944


<210>  1528
<211>  1031
<212>  DNA
<213>  homo sapiens

<400>  1528
cgacagccgg aagtcccgcc tgccgtgtag tcgccgccgt cgctgccgct gccgctgccg       60

ccgtcgttgt tgttgtgctc ggtgcgctga gctccgcggc tccgcgagcc ggttccgtcc      120

ccttcccgcc gccgccatga agtggatgtt caaggaggac cactcgctgg aacacagatg      180

cgtggagtcc gcgaagattc gagcgaaata tcccgacagg gttccggtga ttgtggaaaa      240

ggtctcaggc tctcagattg ttgacattga caaacggaag tacttggttc catctgatat      300

cactgtggct cagttcatgt ggatcatcag gaaaaggatc cagcttcctt ctgaaaaggc      360

gatcttcctg tttgtggata agacagtccc acagtccagc ctaactatgg gacagcttta      420

cgagaaggaa aaagatgaag atggattctt atatgtggcc tacagcggag agaacacttt      480

tggcttctga gggccattgc tgggctaggt gcaccgtaac tgcttgtgta tcttgtaaat      540

agccagccat tttcagttat tataccagaa cctcttcaca tagacctatt agtgcatttg      600

taactggatt tatttcttaa tatattggaa ggttttgttt ccttagacta gtaaattatc      660

atacagagtt ttattttgag tttttctttt tgtgcattgt cctcatgcct gtattctcca      720

ggaaacttgt ccttctggaa atcatattga atgatatttc tatatcgaag tgaggtaggt      780

gcggtattaa agtgaaaggg aaggtgatgc atttattctg ggttatgctt gaagtgttag      840

atggctaagt attaaaatta tccaaattaa atccttagca gtcagaacac ttgcttcact      900

agaatatgcc aactgccaat catgttggac tgagctaatt tgttcctctt tctgaaacta      960

ttaaggtaaa taattaacaa taaaaattct cttataaagg caaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa a                                                          1031


<210>  1529
<211>  1031
<212>  DNA
<213>  homo sapiens

<400>  1529
cgacagccgg aagtcccgcc tgccgtgtag tcgccgccgt cgctgccgct gccgctgccg       60

ccgtcgttgt tgttgtgctc ggtgcgctga gctccgcggc tccgcgagcc ggttccgtcc      120

ccttcccgcc gccgccatga agtggatgtt caaggaggac cactcgctgg aacacagatg      180

cgtggagtcc gcgaagattc gagcgaaata tcccgacagg gttccggtga ttgtggaaaa      240

ggtctcaggc tctcagattg ttgacattga caaacggaag tacttggttc catctgatat      300

cactgtggct cagttcatgt ggatcatcag gaaaaggatc cagcttcctt ctgaaaaggc      360

gatcttcctg tttgtggata agacagtccc acagtccagc ctaactatgg gacagcttta      420

cgagaaggaa aaagatgaag atggattctt atatgtggcc tacagcggag agaacacttt      480

tggcttctga gggccattgc tgggctaggt gcaccgtaac tgcttgtgta tcttgtaaat      540

agccagccat tttcagttat tataccagaa cctcttcaca tagacctatt agtgcatttg      600

taactggatt tatttcttaa tatattggaa ggttttgttt ccttagacta gtaaattatc      660

atacagagtt ttattttgag tttttctttt tgtgcattgt cctcatgcct gtattctcca      720

ggaaacttgt ccttctggaa atcatattga atgatatttc tatatcgaag tgaggtaggt      780

gcggtattaa agtgaaaggg aaggtgatgc atttattctg ggttatgctt gaagtgttag      840

atggctaagt attaaaatta tccaaattaa atccttagca gtcagaacac ttgcttcact      900

agaatatgcc aactgccaat catgttggac tgagctaatt tgttcctctt tctgaaacta      960

ttaaggtaaa taattaacaa taaaaattct cttataaagg caaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa a                                                          1031


<210>  1530
<211>  5802
<212>  DNA
<213>  homo sapiens

<400>  1530
gccgcccctg agcagcctcg ccttcgcctc ccgcgtttcc tgccgtccgc cctcccccgg       60

ccgagctcca ggggctgccg cctagcagct cccggcggga gagcggttca gagcgcgcac      120

gggggcgggc ggaggcggcc cggtgcgggg cggccgcgct ggagagaggc gcgcgcggag      180

acgccggccc ccctctccgc gtttgctcgc ttgctccccg cctcccgcac tccgctcgct      240

cccacccctt cccggcgtga ttgatccgtc acgggcgccg ccgctgccgc cgccgccgcc      300

gcggccgttc tgagccgagc cggaacccta gcccgagacg gagccggggc ccgggccggc      360

gccattgcgc gggcgccgcg ggaagacctt ggcgcggggc ggcgggccgg gccaggccat      420

gcgggccgag tgagccggcg cccgcagccc gcggcgcggc atggcttccc cgcggagctc      480

cgggcagccc gggccgccgc cgccgccgcc accgccgccc gcgcgcctgc tactgctact      540

gctgctgccg ctgctgctgc ctctggcgcc cggggcctgg ggctgggcgc ggggcgcccc      600

ccggccgccg cccagcagcc cgccgctctc catcatgggc ctcatgccgc tcaccaagga      660

ggtggccaag ggcagcatcg ggcgcggtgt gctccccgcc gtggaactgg ccatcgagca      720

gatccgcaac gagtcactcc tgcgccccta cttcctcgac ctgcggctct atgacacgga      780

gtgcgacaac gcaaaagggt tgaaagcctt ctacgatgca ataaaatacg ggcctaacca      840

cttgatggtg tttggaggcg tctgtccatc cgtcacatcc atcattgcag agtccctcca      900

aggctggaat ctggtgcagc tttcttttgc tgcaaccacg cctgttctag ccgataagaa      960

aaaataccct tatttctttc ggaccgtccc atcagacaat gcggtgaatc cagccattct     1020

gaagttgctc aagcactacc agtggaagcg cgtgggcacg ctgacgcaag acgttcagag     1080

gttctctgag gtgcggaatg acctgactgg agttctgtat ggcgaggaca ttgagatttc     1140

agacaccgag agcttctcca acgatccctg taccagtgtc aaaaagctga aggggaatga     1200

tgtgcggatc atccttggcc agtttgacca gaatatggca gcaaaagtgt tctgttgtgc     1260

atacgaggag aacatgtatg gtagtaaata tcagtggatc attccgggct ggtacgagcc     1320

ttcttggtgg gagcaggtgc acacggaagc caactcatcc cgctgcctcc ggaagaatct     1380

gcttgctgcc atggagggct acattggcgt ggatttcgag cccctgagct ccaagcagat     1440

caagaccatc tcaggaaaga ctccacagca gtatgagaga gagtacaaca acaagcggtc     1500

aggcgtgggg cccagcaagt tccacgggta cgcctacgat ggcatctggg tcatcgccaa     1560

gacactgcag agggccatgg agacactgca tgccagcagc cggcaccagc ggatccagga     1620

cttcaactac acggaccaca cgctgggcag gatcatcctc aatgccatga acgagaccaa     1680

cttcttcggg gtcacgggtc aagttgtatt ccggaatggg gagagaatgg ggaccattaa     1740

atttactcaa tttcaagaca gcagggaggt gaaggtggga gagtacaacg ctgtggccga     1800

cacactggag atcatcaatg acaccatcag gttccaagga tccgaaccac caaaagacaa     1860

gaccatcatc ctggagcagc tgcggaagat ctccctacct ctctacagca tcctctctgc     1920

cctcaccatc ctcgggatga tcatggccag tgcttttctc ttcttcaaca tcaagaaccg     1980

gaatcagaag ctcataaaga tgtcgagtcc atacatgaac aaccttatca tccttggagg     2040

gatgctctcc tatgcttcca tatttctctt tggccttgat ggatcctttg tctctgaaaa     2100

gacctttgaa acactttgca ccgtcaggac ctggattctc accgtgggct acacgaccgc     2160

ttttggggcc atgtttgcaa agacctggag agtccacgcc atcttcaaaa atgtgaaaat     2220

gaagaagaag atcatcaagg accagaaact gcttgtgatc gtggggggca tgctgctgat     2280

cgacctgtgt atcctgatct gctggcaggc tgtggacccc ctgcgaagga cagtggagaa     2340

gtacagcatg gagccggacc cagcaggacg ggatatctcc atccgccctc tcctggagca     2400

ctgtgagaac acccatatga ccatctggct tggcatcgtc tatgcctaca agggacttct     2460

catgttgttc ggttgtttct tagcttggga gacccgcaac gtcagcatcc ccgcactcaa     2520

cgacagcaag tacatcggga tgagtgtcta caacgtgggg atcatgtgca tcatcggggc     2580

cgctgtctcc ttcctgaccc gggaccagcc caatgtgcag ttctgcatcg tggctctggt     2640

catcatcttc tgcagcacca tcaccctctg cctggtattc gtgccgaagc tcatcaccct     2700

gagaacaaac ccagatgcag caacgcagaa caggcgattc cagttcactc agaatcagaa     2760

gaaagaagat tctaaaacgt ccacctcggt caccagtgtg aaccaagcca gcacatcccg     2820

cctggagggc ctacagtcag aaaaccatcg cctgcgaatg aagatcacag agctggataa     2880

agacttggaa gaggtcacca tgcagctgca ggacacacca gaaaagacca cctacattaa     2940

acagaaccac taccaagagc tcaatgacat cctcaacctg ggaaacttca ctgagagcac     3000

agatggagga aaggccattt taaaaaatca cctcgatcaa aatccccagc tacagtggaa     3060

cacaacagag ccctctcgaa catgcaaaga tcctatagaa gatataaact ctccagaaca     3120

catccagcgt cggctgtccc tccagctccc catcctccac cacgcctacc tcccatccat     3180

cggaggcgtg gacgccagct gtgtcagccc ctgcgtcagc cccaccgcca gcccccgcca     3240

cagacatgtg ccaccctcct tccgagtcat ggtctcgggc ctgtaagggt gggaggcctg     3300

ggcccggggc ctcccccgtg acagaaccac actgggcaga ggggtctgct gcagaaacac     3360

tgtcggctct ggctgcggag aagctgggca ccatggctgg cctctcagga ccactcggat     3420

ggcactcagg tggacaggac ggggcagggg gagacttggc acctgacctc gagccttatt     3480

tgtgaagtcc ttatttcttc acaaagaaga ggaacggaaa tgggacgtct tccttaacat     3540

ctgcaaacaa ggaggcgctg ggatatcaaa cttgcaaaaa aaaaaaaaaa aaaaaaaaaa     3600

caaaaaaact agacaaggag agaggcacta gaactccagc tggaagtcac ggagtggctc     3660

gagcagcctt gggaagaggc aaggagcttc tgaagaaact gcctctgcac acacatcact     3720

ggctgtgacc cctcaggcta gcccttctcc actctggggg aggaggtggg aagggccacc     3780

aggcccccag ctgccaggcc agctgacccc agccttcctg gaacagggag tctgcaggag     3840

cgcagacagg cacagccctg gagcaggcag gccgagggct gcggcactgg agcaggctga     3900

cttacatgct ccacatggga cctgtgtcac ccaatgagat gtttgttact ctggtaaatg     3960

ccacacgtta acacaataac acccattcct gggaccgtgg ggatttaggg cacgtcactg     4020

cagacacgct ctgcagcatt caccgacagt ctgtcatgca cccaccacgt tggccatgtc     4080

cttgtgttcc tatcggatgc tcccagtaac cagggggacc acccgagcta atcatggaat     4140

gtctgttccc agcaaacacg ataaagaaag attgtgcact ttaacctctc tcatcagggc     4200

ccaagggctg gctgggattt tttttttttt tttcccacta actttgtttc tgaccaaagt     4260

gaattggagg cactctgcta aaagacatcc ccgtagacat aggggagaga gttgctggct     4320

gagggcttcc cttggcttcc agaaggcagc cttccatcca gacaagccag tgagctctcc     4380

ccttgggatc actggggtga tcagtcagca gattgattct cattcataag atcattcctc     4440

cctttaaatt gagcccctaa gagcactggc ctgggagtca gacagacctg ggttcaagtc     4500

ctcagtcccc tgcccactcc ctacgtgact ttgatcaggt cactagtgtc tctctgagcc     4560

tcagtttccc ctctgtaact tggggttgaa ctaaaacacc tgtcctgcct acctcacaag     4620

gtcactctga ggattgaaac ttgatcttgt ccaggaaagc tttgtaccaa acagtgaagc     4680

cgccctgatc cgtgaggtat gagtatgact ctgaccttca gccctcccta cagccggggg     4740

tgtggcccag agaagcttcc agcacagccc tctacccaga acatccgggc tggagggagg     4800

ctcccagtga cttttctgac attcctagac aggttcattc tttgctcaag aaaggcctga     4860

atgacaatgt ccaggatgtc tgcacaactg agcagctcgc tcactcccta aagaaaccta     4920

ttggcagctt caacaggcag gcaataatct cttcccagaa ccactgcagt caggaataaa     4980

ctgttttctc caccaggctt tgacaaaagg gcccacagga atcttaccaa tgccaacatt     5040

tcaaagcacc ctatttcacg tagcatagct ttctgctccc cttccccaaa gagaggttat     5100

ggaggtactg tagcttttag ggaaaaaaaa atgttaacac atcacaggtc aagttgaagt     5160

cattctctgt ttaggcacta aaaatcggtg ttgtcactca ctgtgtatta ccagtattta     5220

cttgctttct tgatttcacc aaaaccaaat ttaatttaaa ggaccacatt aatttttcaa     5280

agggaaagag acaattaatt gtacataatg tatacacaca cacaaaaaaa aatacctgta     5340

gaaatattat tccagcatag caggaaaaca aacaaaagta ttggactgtc ggaggtgagc     5400

ctgtgcgtct gtaacccttt gtgactcctg agcgtgcgct gtcttctagg ttaactcacg     5460

aagtacattc tctgtcttac tgatactgta ggttcaccca ttttttttta atttcctcgc     5520

aaataacaag acccacagaa gtgactctag ctacttaatg gttctgttct tttatatgca     5580

gcaaacacac cgtccatttc tgaagaggct tcggcctgaa ggcattttcc aatgatgtta     5640

gtgcacaaaa cgctttaaat tagactggaa ctgccagaat caaatgtaaa tgaggaattt     5700

ctcgtacccc tactgcatgg tatcgatttt taataaattg ttgcaaattt gtttttatga     5760

ataaaaggaa aaaacctgtc gtctttaaaa aaaaaaaaaa aa                        5802


<210>  1531
<211>  5802
<212>  DNA
<213>  homo sapiens

<400>  1531
gccgcccctg agcagcctcg ccttcgcctc ccgcgtttcc tgccgtccgc cctcccccgg       60

ccgagctcca ggggctgccg cctagcagct cccggcggga gagcggttca gagcgcgcac      120

gggggcgggc ggaggcggcc cggtgcgggg cggccgcgct ggagagaggc gcgcgcggag      180

acgccggccc ccctctccgc gtttgctcgc ttgctccccg cctcccgcac tccgctcgct      240

cccacccctt cccggcgtga ttgatccgtc acgggcgccg ccgctgccgc cgccgccgcc      300

gcggccgttc tgagccgagc cggaacccta gcccgagacg gagccggggc ccgggccggc      360

gccattgcgc gggcgccgcg ggaagacctt ggcgcggggc ggcgggccgg gccaggccat      420

gcgggccgag tgagccggcg cccgcagccc gcggcgcggc atggcttccc cgcggagctc      480

cgggcagccc gggccgccgc cgccgccgcc accgccgccc gcgcgcctgc tactgctact      540

gctgctgccg ctgctgctgc ctctggcgcc cggggcctgg ggctgggcgc ggggcgcccc      600

ccggccgccg cccagcagcc cgccgctctc catcatgggc ctcatgccgc tcaccaagga      660

ggtggccaag ggcagcatcg ggcgcggtgt gctccccgcc gtggaactgg ccatcgagca      720

gatccgcaac gagtcactcc tgcgccccta cttcctcgac ctgcggctct atgacacgga      780

gtgcgacaac gcaaaagggt tgaaagcctt ctacgatgca ataaaatacg ggcctaacca      840

cttgatggtg tttggaggcg tctgtccatc cgtcacatcc atcattgcag agtccctcca      900

aggctggaat ctggtgcagc tttcttttgc tgcaaccacg cctgttctag ccgataagaa      960

aaaataccct tatttctttc ggaccgtccc atcagacaat gcggtgaatc cagccattct     1020

gaagttgctc aagcactacc agtggaagcg cgtgggcacg ctgacgcaag acgttcagag     1080

gttctctgag gtgcggaatg acctgactgg agttctgtat ggcgaggaca ttgagatttc     1140

agacaccgag agcttctcca acgatccctg taccagtgtc aaaaagctga aggggaatga     1200

tgtgcggatc atccttggcc agtttgacca gaatatggca gcaaaagtgt tctgttgtgc     1260

atacgaggag aacatgtatg gtagtaaata tcagtggatc attccgggct ggtacgagcc     1320

ttcttggtgg gagcaggtgc acacggaagc caactcatcc cgctgcctcc ggaagaatct     1380

gcttgctgcc atggagggct acattggcgt ggatttcgag cccctgagct ccaagcagat     1440

caagaccatc tcaggaaaga ctccacagca gtatgagaga gagtacaaca acaagcggtc     1500

aggcgtgggg cccagcaagt tccacgggta cgcctacgat ggcatctggg tcatcgccaa     1560

gacactgcag agggccatgg agacactgca tgccagcagc cggcaccagc ggatccagga     1620

cttcaactac acggaccaca cgctgggcag gatcatcctc aatgccatga acgagaccaa     1680

cttcttcggg gtcacgggtc aagttgtatt ccggaatggg gagagaatgg ggaccattaa     1740

atttactcaa tttcaagaca gcagggaggt gaaggtggga gagtacaacg ctgtggccga     1800

cacactggag atcatcaatg acaccatcag gttccaagga tccgaaccac caaaagacaa     1860

gaccatcatc ctggagcagc tgcggaagat ctccctacct ctctacagca tcctctctgc     1920

cctcaccatc ctcgggatga tcatggccag tgcttttctc ttcttcaaca tcaagaaccg     1980

gaatcagaag ctcataaaga tgtcgagtcc atacatgaac aaccttatca tccttggagg     2040

gatgctctcc tatgcttcca tatttctctt tggccttgat ggatcctttg tctctgaaaa     2100

gacctttgaa acactttgca ccgtcaggac ctggattctc accgtgggct acacgaccgc     2160

ttttggggcc atgtttgcaa agacctggag agtccacgcc atcttcaaaa atgtgaaaat     2220

gaagaagaag atcatcaagg accagaaact gcttgtgatc gtggggggca tgctgctgat     2280

cgacctgtgt atcctgatct gctggcaggc tgtggacccc ctgcgaagga cagtggagaa     2340

gtacagcatg gagccggacc cagcaggacg ggatatctcc atccgccctc tcctggagca     2400

ctgtgagaac acccatatga ccatctggct tggcatcgtc tatgcctaca agggacttct     2460

catgttgttc ggttgtttct tagcttggga gacccgcaac gtcagcatcc ccgcactcaa     2520

cgacagcaag tacatcggga tgagtgtcta caacgtgggg atcatgtgca tcatcggggc     2580

cgctgtctcc ttcctgaccc gggaccagcc caatgtgcag ttctgcatcg tggctctggt     2640

catcatcttc tgcagcacca tcaccctctg cctggtattc gtgccgaagc tcatcaccct     2700

gagaacaaac ccagatgcag caacgcagaa caggcgattc cagttcactc agaatcagaa     2760

gaaagaagat tctaaaacgt ccacctcggt caccagtgtg aaccaagcca gcacatcccg     2820

cctggagggc ctacagtcag aaaaccatcg cctgcgaatg aagatcacag agctggataa     2880

agacttggaa gaggtcacca tgcagctgca ggacacacca gaaaagacca cctacattaa     2940

acagaaccac taccaagagc tcaatgacat cctcaacctg ggaaacttca ctgagagcac     3000

agatggagga aaggccattt taaaaaatca cctcgatcaa aatccccagc tacagtggaa     3060

cacaacagag ccctctcgaa catgcaaaga tcctatagaa gatataaact ctccagaaca     3120

catccagcgt cggctgtccc tccagctccc catcctccac cacgcctacc tcccatccat     3180

cggaggcgtg gacgccagct gtgtcagccc ctgcgtcagc cccaccgcca gcccccgcca     3240

cagacatgtg ccaccctcct tccgagtcat ggtctcgggc ctgtaagggt gggaggcctg     3300

ggcccggggc ctcccccgtg acagaaccac actgggcaga ggggtctgct gcagaaacac     3360

tgtcggctct ggctgcggag aagctgggca ccatggctgg cctctcagga ccactcggat     3420

ggcactcagg tggacaggac ggggcagggg gagacttggc acctgacctc gagccttatt     3480

tgtgaagtcc ttatttcttc acaaagaaga ggaacggaaa tgggacgtct tccttaacat     3540

ctgcaaacaa ggaggcgctg ggatatcaaa cttgcaaaaa aaaaaaaaaa aaaaaaaaaa     3600

caaaaaaact agacaaggag agaggcacta gaactccagc tggaagtcac ggagtggctc     3660

gagcagcctt gggaagaggc aaggagcttc tgaagaaact gcctctgcac acacatcact     3720

ggctgtgacc cctcaggcta gcccttctcc actctggggg aggaggtggg aagggccacc     3780

aggcccccag ctgccaggcc agctgacccc agccttcctg gaacagggag tctgcaggag     3840

cgcagacagg cacagccctg gagcaggcag gccgagggct gcggcactgg agcaggctga     3900

cttacatgct ccacatggga cctgtgtcac ccaatgagat gtttgttact ctggtaaatg     3960

ccacacgtta acacaataac acccattcct gggaccgtgg ggatttaggg cacgtcactg     4020

cagacacgct ctgcagcatt caccgacagt ctgtcatgca cccaccacgt tggccatgtc     4080

cttgtgttcc tatcggatgc tcccagtaac cagggggacc acccgagcta atcatggaat     4140

gtctgttccc agcaaacacg ataaagaaag attgtgcact ttaacctctc tcatcagggc     4200

ccaagggctg gctgggattt tttttttttt tttcccacta actttgtttc tgaccaaagt     4260

gaattggagg cactctgcta aaagacatcc ccgtagacat aggggagaga gttgctggct     4320

gagggcttcc cttggcttcc agaaggcagc cttccatcca gacaagccag tgagctctcc     4380

ccttgggatc actggggtga tcagtcagca gattgattct cattcataag atcattcctc     4440

cctttaaatt gagcccctaa gagcactggc ctgggagtca gacagacctg ggttcaagtc     4500

ctcagtcccc tgcccactcc ctacgtgact ttgatcaggt cactagtgtc tctctgagcc     4560

tcagtttccc ctctgtaact tggggttgaa ctaaaacacc tgtcctgcct acctcacaag     4620

gtcactctga ggattgaaac ttgatcttgt ccaggaaagc tttgtaccaa acagtgaagc     4680

cgccctgatc cgtgaggtat gagtatgact ctgaccttca gccctcccta cagccggggg     4740

tgtggcccag agaagcttcc agcacagccc tctacccaga acatccgggc tggagggagg     4800

ctcccagtga cttttctgac attcctagac aggttcattc tttgctcaag aaaggcctga     4860

atgacaatgt ccaggatgtc tgcacaactg agcagctcgc tcactcccta aagaaaccta     4920

ttggcagctt caacaggcag gcaataatct cttcccagaa ccactgcagt caggaataaa     4980

ctgttttctc caccaggctt tgacaaaagg gcccacagga atcttaccaa tgccaacatt     5040

tcaaagcacc ctatttcacg tagcatagct ttctgctccc cttccccaaa gagaggttat     5100

ggaggtactg tagcttttag ggaaaaaaaa atgttaacac atcacaggtc aagttgaagt     5160

cattctctgt ttaggcacta aaaatcggtg ttgtcactca ctgtgtatta ccagtattta     5220

cttgctttct tgatttcacc aaaaccaaat ttaatttaaa ggaccacatt aatttttcaa     5280

agggaaagag acaattaatt gtacataatg tatacacaca cacaaaaaaa aatacctgta     5340

gaaatattat tccagcatag caggaaaaca aacaaaagta ttggactgtc ggaggtgagc     5400

ctgtgcgtct gtaacccttt gtgactcctg agcgtgcgct gtcttctagg ttaactcacg     5460

aagtacattc tctgtcttac tgatactgta ggttcaccca ttttttttta atttcctcgc     5520

aaataacaag acccacagaa gtgactctag ctacttaatg gttctgttct tttatatgca     5580

gcaaacacac cgtccatttc tgaagaggct tcggcctgaa ggcattttcc aatgatgtta     5640

gtgcacaaaa cgctttaaat tagactggaa ctgccagaat caaatgtaaa tgaggaattt     5700

ctcgtacccc tactgcatgg tatcgatttt taataaattg ttgcaaattt gtttttatga     5760

ataaaaggaa aaaacctgtc gtctttaaaa aaaaaaaaaa aa                        5802


<210>  1532
<211>  5182
<212>  DNA
<213>  homo sapiens

<400>  1532
cgaccggacg ggtctaggtg agacagaagc caaacaggag gaggaagtgg agggtaagtg       60

cttccgggtc ccctggcaca gcctccgcca tcttttcttc gcctaatttg acccgttctt      120

tttcccctcc ttgaaacctt gctctgtacg catgcgctct ttgagtggcc tttcccctag      180

ttcaagctcc cctccgagtc agcgtcctgt tcgttagggt tatcgaagtg tataaaggtg      240

cagggaaagt gagactgtgt aaaacaaagc ggattggggc gttgtgcttc cttgtacctc      300

gtgagcctcc gttgccttgg gcggtcgttt tgcgcaccct gccgggagtt gtagtcctgg      360

acccgaaggt gcctgggagg cgggaggggg gttggggctt ctcagcgccg attccgcggg      420

aagggccctg ggacctcaca cttctagtcg cgggagctgc aggtcttacc cggagagacg      480

ctgcacgtgg agccctcgcc gctgccgttc tcagccggct ctggagtgcg ggcgggggcg      540

acagggccga ttccggagtg ggactgatcc tttgaaatac tccagccatg actaaaagag      600

aagcagagga gctgatagaa attgagattg atggaacaga gaaagcagag tgcacagaag      660

aaagcattgt agaacaaacc tacgcgccag ctgaatgtgt aagccaggcc atagacatca      720

atgaaccaat aggcaattta aagaaactgc tagaaccaag actacagtgt tctttggatg      780

ctcatgaaat ttgtctgcaa gatatccagc tggatccaga acgaagttta tttgaccaag      840

gagtaaaaac agatggaact gtacagctta gtgtacaggt aatttcttac caaggaattg      900

aaccaaagtt aaacatcctt gaaattgtta aacctgcgga cactgttgag gttgttattg      960

atccagatgc ccaccatgct gaatcagaag cacatcttgt tgaagaagct caagtgataa     1020

ctcttgatgg cacaaaacac atcacaacca tttcagatga aacttcagaa caagtgacaa     1080

gatgggctgc tgcactggaa ggctatagga aagaacaaga acgccttggg ataccctatg     1140

atcccataca gtggtccaca gaccaagtcc tgcattgggt ggtttgggta atgaaggaat     1200

tcagcatgac cgatatagac ctcaccacac tcaacatttc ggggagagaa ttatgtagtc     1260

tcaaccaaga agattttttt cagcgggttc ctcggggaga aattctctgg agtcatctgg     1320

aacttctccg aaaatatgta ttggcaagtc aagaacaaca gatgaatgaa atagttacaa     1380

ttgatcaacc tgtgcaaatt attccagcat cagtgcaatc tgctacacct actaccatta     1440

aagttataaa tagtagtgcg aaagcagcca aagtacaaag agcgccgagg atttcaggag     1500

aagatagaag ctcacctggg aacagaacag gaaacaatgg ccaaatccaa ctatggcagt     1560

ttttgctaga acttcttact gataaggacg ctcgagactg catttcttgg gttggtgatg     1620

aaggtgaatt taagctaaat cagcctgaac tggttgcaca gaaatgggga cagcgtaaaa     1680

ataagcctac gatgaactat gagaaactca gtcgtgcatt aagatattat tacgatgggg     1740

acatgatttg taaagttcaa ggcaagagat ttgtgtacaa gtttgtctgt gacttgaaga     1800

ctcttattgg atacagtgca gcggagttga accgtttggt cacagaatgt gaacagaaga     1860

aacttgcaaa gatgcagctc catggaattg cccagccagt cacagcagta gctctggcta     1920

ctgcttctct gcaaacggaa aaggataatt gagccccagg acattctgag actccaaagt     1980

ctttcttaaa atgtttagag caagtatagc tcttaccttt attactgaat ttgaatcttc     2040

ttttatttct aggctgtaca gtctgatgca tgattttttt ataaatattt catactcttg     2100

tgaatttgga tctttttact ttgagcatat attttagaat atgtgtatgt taaaggatct     2160

ccacaatgtc tgcagtgtga aggcaggttc attgtggaat agtttaacag tcaggaaggc     2220

taaactggtc agtattaatg tgtagcccta ccaaaaatag ccagtagtat ctgaaaatga     2280

aaaataaatg aagtatctct aggaaacagt ctggcttaac tatttttgaa aatataactg     2340

tttcccctct ctgctgcttt agatgttgct ttacatagaa ccagaaaatg gaatttctca     2400

gctaaagcat gtgtgcctgt ttcatctaat caagcagagc taaaatgttc ataccgaata     2460

aatttatatt aataaattac taaactaaga gtatcaggtt atttatatat ttgcaagcaa     2520

aggacagtaa gaagttgact ggcaaaagag cagtgctgaa ggaggagatc caggtttaaa     2580

tctggcttat taactcaagc caattttaag gattttctgt atagattact catgtcagac     2640

caagaattta aattattttg agagaggcat ttaattctaa taaaccagct gttataaaaa     2700

ttataaaatg atctctgttt ttcctgtcag agatttaaaa aactgaaaag gtatacctca     2760

acccaaaaat aaaggtttgt tttggtttgt tatggcttcc ttttttaaaa aattaccctg     2820

tagtgccagt ttattatgca aagcagctta tattcctttg tttctgataa aatgaagact     2880

ttaaatcagt cagtagtact ttacctttca aggcattagt aaattacttg caaatagttt     2940

taaaaggaaa atacgacctt tgttataggc agtcttctct ttaagacaat acttttccac     3000

ttgttttcct tttccatatt atatatgtgt attcatatag ctgtatacat attcagttga     3060

tcattttata aacatatgaa ggcataaaga tatacagaag aaaaattatt aaacaactca     3120

ttttaagatt caaattaact aattcctgca tatatgacat tccttacata agcgaacact     3180

aaacaaaaat ggctagaaat gtctttttct ttcttttctc tctttgttgt ttaaggtatt     3240

aagcacgaat tattacatga gactggcaga tagctattaa tcctcttaca gatttgagaa     3300

agttgattct caaatattta tgcaccttct ccttcattgt tttctttaaa tctgtcctct     3360

taaaaagctt cttaagagct cagttaatgc ttttgactta actaggagaa aaaggcatga     3420

taatacaggc aagatggcat tgttagcaat tctggtagtg gtttggaatg aatcctaaga     3480

ggcagggatc ttaaggacaa ggaagagaag agagagaggg agggatcttt gatctctttc     3540

tctggtaatc ttaatgcata attttactaa aacatgttct caattcattc atattattaa     3600

gctcttcctg cagttgatat ctgagcagag taagatttgt atttccattt ttactttttt     3660

gaaagagaat atatggacag attattagta caatttgggc actgtggttt taagaatatc     3720

tgagtaaaat aacaatatga aataataaac agaagctcta acgtcaggta acaaatagac     3780

agcaagaaag gttttgcacc atcctcttac ggcctagaga gttgacaagt tgcttgtagt     3840

tttaaaaaaa taataaagta tacccttctg gtatatcatc aagagcttaa gaatcttggc     3900

tttcatattt aaaatgcttt tggggagaca tatattaaaa ttttagccaa gatgatagac     3960

atgtctcaat tatatatgtg tgtgtatgtt tttaaagcta aaaacattac ttttagatcc     4020

ctagaatgaa aatttttttc tcatctatgc aattcccata tggttttttt ttaaatcata     4080

ttttattcat tttctccctt tagcaatttt cattttattt ctcataattt gaacagagac     4140

agttctcata catgatcaga tgcttttttt ttcttcttac catcatttat gcatgacata     4200

ggtaatgtga ctaatttctc cagttgattc aagaaactca ttactttgcc tcaaattata     4260

tgtaaaatat ttgttttact taggttacag ttatcagaaa ggtagttttt ttcttctatt     4320

aaaatataac attgtgaaag aaaataaaat ttatgctatt ctttgctttg tttttataaa     4380

tgaatttttc atagaattta cagtatattc aaaggaagaa agataaaatt attggtcatc     4440

atttgtacct tagaagtaca agaatttaag taaaagaaat gttcattttt gttttaaaat     4500

ttgttttcca tgtgaagttt ttattgagcc aactttcata catatcttgc tagcctaaag     4560

tctaaatatt tgtgttggca tcagaaaaac aaatgaggca gaattgctat gtgtggttga     4620

tcttcagata aattgactga tcacagttat ttttgtatca gtctatgtta ttaggaaaaa     4680

ttgtttagtt gttttctccc ctgattaatg gtgatattca agtatgatac aaaaagaatt     4740

gtaccaccaa atatttttgt gaggtctgct gttttccata ttcattttat gctactgcct     4800

ttaagaaaga actagtgtat ccttgaaata gcacaaaaat gttttaaaat tcataattgc     4860

aaaacaaatc tgtgactaac ttaatgtctt cagatctaaa gggtgtaaaa atattgatac     4920

ttcaatattt cacttgctgc caggaaaaac aaaattctca atcttttgta aatgggagga     4980

ggacttttgc atacattttt actctttaaa taacgacaac gacacttata ctgtcataat     5040

aacaattatg tatttctttg tggttttaat tttttttgta attttacata aaacagttat     5100

tttctatttt tacgcagata aatatttgtg cataaaatgt aaaaatagta aaatgagaaa     5160

aataaaacta ttatacagta aa                                              5182


<210>  1533
<211>  4333
<212>  DNA
<213>  homo sapiens

<400>  1533
gagaaaatca attggtttag aaggtttgga ctcacttgac aggttcagtt ggagacgatc       60

ataggtggct gctgtgacaa agggaaattg tgcttttcca gcatgcttac tgaccctgat      120

ttacctcagg agtttgaaag gatgtcttcc aagcgaccag cctctccgta tggggaagca      180

gatggagagg tagccatggt gacaagcaga cagaaagtgg aagaagagga gagtgacggg      240

ctcccagcct ttcaccttcc cttgcatgtg agttttccca acaagcctca ctctgaggaa      300

tttcagccag tttctctgct gacgcaagag acttgtggcc ataggactcc cacttctcag      360

cacaatacaa tggaagttga tggcaataaa gttatgtctt catttgcccc acacaactca      420

tctacctcac ctcagaaggc agaagaaggt gggcgacaga gtggcgagtc cttgtctagt      480

acagccctgg gaactcctga acggcgcaag ggcagtttag ctgatgttgt tgacaccttg      540

aagcagagga aaatggaaga gctcatcaaa aacgagccgg aagaaacccc cagtattgaa      600

aaactactct caaaggactg gaaagacaag cttcttgcaa tgggatcggg gaactttggc      660

gaaataaaag ggactcccga gagcttagct gagaaagaaa ggcaactcat gggtatgatc      720

aaccagctga ccagcctccg agagcagctg ttggctgccc acgatgagca gaagaaacta      780

gctgcctctc agattgagaa acagcgtcag caaatggagc tggccaagca gcaacaagaa      840

caaattgcaa gacagcagca gcagcttcta cagcaacaac acaaaatcaa tttgctccag      900

caacagatcc aggttcaagg tcagctgccg ccattaatga ttcccgtatt ccctcctgat      960

caacggacac tggctgcagc tgcccagcaa ggattcctcc tccctccagg cttcagctat     1020

aaggctggat gtagtgaccc ttaccctgtt cagctgatcc caactaccat ggcagctgct     1080

gccgcagcaa caccaggctt aggcccactc caactgcagc agttatatgc tgcccagcta     1140

gctgcaatgc aggtatctcc aggagggaag ctgccaggca taccccaagg caaccttggt     1200

gctgctgtat ctcctaccag cattcacaca gacaagagca caaacagccc accacccaaa     1260

agcaaggatg aagtggcaca gccactgaac ctatcagcta aacccaagac ctctgatggc     1320

aaatcaccca catcacccac ctctccccat atgccagctc tgagaataaa cagtggggca     1380

ggccccctca aagcctctgt cccagcagcg ttagctagtc cttcagccag agttagcaca     1440

ataggttact taaatgacca tgatgctgtc accaaggcaa tccaagaagc tcggcaaatg     1500

aaggagcaac tccgacggga acaacaggtg cttgatggga aggtggctgt tgtgaatagt     1560

ctgggtctca ataactgccg aacagaaaag gaaaaaacaa cactggagag tctgactcag     1620

caactggcag ttaaacagaa tgaagaagga aaatttagcc atgcaatgat ggatttcaat     1680

ctgagtggag attctgatgg aagtgctgga gtctcagagt caagaattta tagggaatcc     1740

cgagggcgtg gtagcaatga accccacata aagcgtccaa tgaatgcctt catggtgtgg     1800

gctaaagatg aacggagaaa gatccttcaa gcctttcctg acatgcacaa ctccaacatc     1860

agcaagatat tgggatctcg ctggaaagct atgacaaacc tagagaaaca gccatattat     1920

gaggagcaag cccgtctcag caagcagcac ctggagaagt accctgacta taagtacaag     1980

cccaggccaa agcgcacctg cctggtggat ggcaaaaagc tgcgcattgg tgaatacaag     2040

gcaatcatgc gcaacaggcg gcaggaaatg cggcagtact tcaatgttgg gcaacaagca     2100

cagatcccca ttgccactgc tggtgttgtg taccctggag ccatcgccat ggctgggatg     2160

ccctcccctc acctgccctc ggagcactca agcgtgtcta gcagcccaga gcctgggatg     2220

cctgttatcc agagcactta cggtgtgaaa ggagaggagc cacatatcaa agaagagata     2280

caggccgagg acatcaatgg agaaatttat gatgagtacg acgaggaaga ggatgatcca     2340

gatgtagatt atgggagtga cagtgaaaac catattgcag gacaagccaa ctgataaggg     2400

tcaaaagatt gttgtgacct taggacttaa agaagcccta actggttcat ccttaccagt     2460

ggccaagcac attaactttc tcatacactg actgttactt taactgttag tcttaaatag     2520

ttgggacatc agctgactaa tagacctcag cctcaaaagg cttggaaaga aaaaacaaat     2580

acaacaagca aacaacaata tcaacaacaa gagattgaaa taagctatgg gtaaaataat     2640

gccagtaatt cagctgctac atccaagcac tgaagtctta cccgtcaact tttttttttt     2700

tttaaataaa ctttatggct gtttgttcta caatgttcta gaaattctca ctcaggtaca     2760

cagtgccaac aagtggcttg tgaatgtgtt ttgttgtttt gtgctacaat ttttaaaaag     2820

aaaaaagttt tgttttgttt tttggggttt ctgggttttt tccttttctt tttctttcct     2880

ttcatttttt ttctttgtaa tgcacctgac agaaaaaaaa gaaaaatgaa tttctcttta     2940

cttctctcca ccttctccat ctctctactt taaagatgga agtctgtgca tgaggggaaa     3000

gagggaaaaa gagcctgttt ttaacttcct tgctatccac cacaaaataa gcaattattt     3060

tctttagagg actttatcta ttgcacacca cactacatct ttgagcaagt gccaaatttg     3120

tactgaagtg ttgaccaagt tcattttttc tctttacttt ttccttttcc ttcttaagtt     3180

aggacagtgt taaatcttag acaatccctt gaaaaacctg aaataccagc agctggtgag     3240

atttgacttt tttttttaat ggaaactgta ggtgctgttc tcaggtgaaa agagagagag     3300

agagagagac ataagaaatt tagagaaaaa tattttctga tcttggattt ttgtgtgtat     3360

gtatgtatgt gattatggta ctaataatag gaataacgtt ggaccattgt gagttaaacc     3420

cacatctggg gatgaaatcc cacatcctcc caagtgactg gtctagaaat aatcttgacc     3480

ttgactttgc acttcaaatg acaacttaac caagtatagg gctcagaaat tatattttta     3540

aatgtctgat tattattgga tggatcaggt ggccctgtgt aatagaggtg tgcatgtata     3600

acatggaagc tactagcaaa ctgctcccag atgtcctttc tccctggtca gttggttcca     3660

ttaacgtttg ctacttagtg atttttgttt ttcctgttga tattttgagc aaaacaatca     3720

ttgttttcat tgaatatatt tggccatttt ttcagacaaa tagaattagc ttatttcttc     3780

aacattccat cctttcccga tcaggaaatg aaactgatga ttttataagg tatttttcac     3840

ccctccatga agtgaggtgg aggcctttag catttcagaa gtgtgggcca tatgtagttc     3900

atgccataaa aagtaggatt taattaaaag tcattgcagc ccaataaaat ggagcctggc     3960

tgcacccagg gatccttgcc actgctcttc ccttgctgtc agattaatcc actgaagtcc     4020

aactttggtt caagcagagt atttgcaaag agcaacaact gaatgtgatg ggactgctta     4080

tgtagatttt gccagccaaa tgccaaggca gttgtagggc ctgtacaaat aaatgcaaaa     4140

tcatttcaag tcaattgcca ttatttgtat tgaagtatca gatagatagt aaatactgca     4200

actagtagct tgatgtgcta tagttttcac tccagtcatc attttcctat ctcacccccc     4260

gaaacaccac cctaaagttg gatttttaca tataaataaa aaaagaatcc cttttaaaaa     4320

aaaaaaaaaa aaa                                                        4333


<210>  1534
<211>  9135
<212>  DNA
<213>  homo sapiens

<400>  1534
ctggcaggaa tttcttgctt ggagctcaga caacaaaggc atagagagat tggttttctt       60

tctctcagca tctccaccca accagcagaa aaccggtctc tgaggttcca ccaaaatatg      120

gaacttgatt ttggacactt tgacgaaaga gataagacat ccaggaacat gcgaggctcc      180

cggatgaatg ggttgcctag ccccactcac agcgcccact gtagcttcta ccgaaccaga      240

accttgcagg cactgagtaa tgagaagaaa gccaagaagg tacgtttcta ccgcaatggg      300

gaccgctact tcaaggggat tgtgtacgct gtgtcctctg accgttttcg cagctttgac      360

gccttgctgg ctgacctgac gcgatctctg tctgacaaca tcaacctgcc tcagggagtg      420

cgttacattt acaccattga tggatccagg aagatcggaa gcatggatga actggaggaa      480

ggggaaagct atgtctgttc ctcagacaac ttctttaaaa aggtggagta caccaagaat      540

gtcaatccca actggtctgt caacgtaaaa acatctgcca atatgaaagc cccccagtcc      600

ttggctagca gcaacagtgc acaggccagg gagaacaagg actttgtgcg ccccaagctg      660

gttaccatca tccgcagtgg ggtgaagcct cggaaggctg tgcgtgtgct tctgaacaag      720

aagacagccc actcttttga gcaagtcctc actgatatca cagaagccat caaactggag      780

accggggttg tcaaaaaact ctacactctg gatggaaaac aggtaacttg tctccatgat      840

ttctttggtg atgatgatgt gtttattgcc tgtggtcctg aaaaatttcg ctatgctcag      900

gatgattttt ctctggatga aaatgaatgc cgagtcatga agggaaaccc atcagccaca      960

gctggcccaa aggcatcccc aacacctcag aagacttcag ccaagagccc tggtcctatg     1020

cgccgaagca agtctccagc tgactcagca aacggaacct ccagcagcca gctctctacc     1080

cccaagtcta agcagtctcc catctctacg cccaccagtc ctggcagcct ccggaagcac     1140

aaggacctgt acctgcctct gtccttggat gactcggact cgcttggtga ttccatgtaa     1200

aggaggggag agtgctcaga gtccagagta caaatccaag cctatcattg tagtagggta     1260

cttctgctca agtgtccaac agggctattg gtgctttcaa gtttttattt tgttgttgtt     1320

gttattttga aaaacacatt gtaatatgtt gggtttattt tcctgtgatt tctcctctgg     1380

gccactgatc cacagttacc aattatgaga gatagattga taaccatcct ttggggcagc     1440

attccaggga tgcaaaatgt gctagtccat gacctttcaa tggaaagctt aggtgcctgc     1500

gttatatttg ccctgtctaa ttttgcccat acagtcttcc ttctgtagag ggctgtttac     1560

atatacagca cttaaaatgt ttgtgtggga aaaaaaaaac tcattggcag atccaagaat     1620

gacaaacaca agtgcccctt ttctctggat ctcaagaatg gtggaggacc ctggaaggac     1680

agcaaggcag ctccccagcc tcactcttca ctcctgattg aggcccgggt ttgttgtcca     1740

gcaccaattc tggctgtcaa tggggagaaa taaaccaaca acttataatt gtgacaccag     1800

atgcttagga tcctggtgct gggttagcta agagaataga cagaattgga aaatactgca     1860

gacatttccg aagagtttat aaagcacagt gaattcctgg tcaatctctc cactgaggca     1920

atttggaatc aataagcaat tgataatagt ttggagtaag ggacttcata tacctgattc     1980

ctctagaagg ctgtctaaca taccacatga ttacatgaac tgtatggtat ccatctatct     2040

ctgttctatt gaatgccttg ttaacagcca acactgaaaa cactgtgaga atttgttttc     2100

aggtctgaca cctttcagtc tctttttata gcaagaaatc aatatccttt ttataaaaat     2160

tcatgtctgt atttcaggag caaactcttc aggctccttt tttataaact ggtgattttt     2220

cttttgtcta aaaaacacat gaagaaaatt taccaaaaaa aaaaaaaaaa gcagaagaat     2280

aatgtagttt agaaattatg ctgtcactgc caaacagtaa cctccaggag aaaacaagat     2340

gaatagcaga ggccaattca atagaatcag ttttttgata gctttttaac agttatgctt     2400

gcattaataa tttcaatgtg gaccagacat tctaattata ttttaaatga aatgttacag     2460

catattttaa gcaactcttt ttatctataa tcctaatatt tcatactgaa gacacagaaa     2520

tctttcactt gtctttaaca ttagaaagga tttctcttta ctaaggactg atcatttgaa     2580

atagttttca gtcttttgag atacaggttt ataacactgc tttttttttt ctgtaatcat     2640

agcccataat ggcaaagaca actaaattta agtgaaggtc atgcatgcca attctgtgtt     2700

tgcttttagc agatatgaag atttccttat ttctttgtaa ttgtgcagat attttgaaag     2760

gcacagcatt cgaagccaag ctgctgtttg gctactgaat ggcttgcagt tgttcctcca     2820

ctctaaatgg aatgagcttg ctgtgtgtgt gtgtggtggt ggtgggaggg ggtggtgcat     2880

gtgtgtgtgt gtgtgtgcat ctgcagctgc ttcaaaatta ggaaatacta caggacaccc     2940

ctgtaatgga ttggtggcaa ctgggtggca ctgctgatgt gcactgtgta ggggggaacc     3000

cagtggtggt ggggtagctc agatgcccct agacaagctt cagatgtctg tagctaccag     3060

aaacattttc ggttcaggaa aagtgagatg atggtagtac tggtttctgg tgaaattgaa     3120

gaaccccaaa tgatgaggat ctctttttgc cccctctcct ttttttgtag acccattcaa     3180

aaccattaat aagcccattt tactaagccc ctatttcttt ctagaagctc agggttttct     3240

tagtgcctcc cagaacattt tgtagttaat tgggaaaaag tgatacttgg attagggggt     3300

gtgggcataa agaatggtgg gaggcctgat tttaaacttc aggccagaac ccccaatgac     3360

tccacccata gtctcacttt aggtctcatt tagtccatca cctttatttt aagttgagga     3420

agtggaggct ggtaaagagc aggaccagag gaagaatcca gatttcctta tgcttgggcc     3480

tcacactagc tctctgagta tttccttgat tgcggtatat gtactactag aaaataccaa     3540

atggatatat tttctttagg ataacctttg aaccaacaat cttcaataac aatagtacat     3600

cttccatctt acttttaatc gagtataagg aaatgtttct ttatggccat tttggaggga     3660

gcaggggatg aggcttggca tagtccaaaa tttaagtctc caataattaa ttgcatttta     3720

aattggccca ctttcaaggc aatttttttt gtgtgtctgt aactgagctc ctccacccct     3780

gtcattcact tccaatttta cccaatccaa ttttagcact caagttccat tgtgttaatt     3840

tctgcacggt caacaaacat caagtcagca agcatttgcc accactccct atacttctcc     3900

ctccttctta cacacacaca cacacacaca cacacaatcc atctcttgct tgttcctacc     3960

tcctgatttt tcttccctac agaaatagaa atagggacaa agaaggggaa aatgtatata     4020

ttggggctgg gctgaacaac taacttcata agtagtatta actaggggta aattgagaga     4080

aaagctcctt ttctcttcac tgttttggaa aggatagcca ttagcatgac tgctttgtgt     4140

ccttatggac tttagtatta gcctagattg aattatagcg ttttctagct ggaaggaacc     4200

ttaagatcac atcatctact cctctactcc aaatttctca ttcttcaggc caggaaaccg     4260

agacacagag gtaaagtaat ttccccaagg tcacacagct ggctggggca ggattgggtt     4320

tacaacccac atctcctggc tcttattcca gggccttttc ccactaagta gtattgcctt     4380

ccattaggct cctgagagtt atttctcagg gtcatgttgc atcttggagc cacatgctgc     4440

tgccctgatc tcagtgggaa atccacccag caacctaata cagccccttt tccctgcatt     4500

cacctggttc ccatccacat gggttgcaga tgtccttgaa gagagtgagg cattgagggc     4560

caataggagc aatggggtcc ctggccttgt ccatctgatt caggagatca ctgctccatc     4620

gtgaggagcc ctctgaatag ccccccactg aatgcttgcc ttgcccaaat ggaatggagg     4680

aagattgatt ttctccatca gttcaccttg tgtcatctca taatggttgg tctttccagg     4740

ctgagggaaa tgtttcttgt ttccagagta gaaaaagaaa gagtggaaca atagctttgt     4800

tcatcctaac tttctgagat ggcttttcaa cattttaaaa aaactagtgt ggctaccatt     4860

cactggcaat gatttctttt agaatatggg agtaagatga gctagagaaa ataacctggt     4920

ctcactgtgg ttgccctcat ccacaatgtc cccaaagcca tcctgctctg atgaggacaa     4980

tttccaggta taagcaaggg gctttgtgac aaaaatgtac cctggctgat gttaaacatt     5040

ggctcctgtg tttgcaccaa aatagcaagc tgtgtgctct atacactctt cccatcgtct     5100

tgtgtacact gctcctgtgg ccttccacag cagaaaccag ggcaaaaggg tccaaacaca     5160

tggttttcct tgctgcaagg ctcttcctgg gaactaaggg ggtatttatt agttcagttc     5220

taagagacct ccttctgggc ttaccccact cctcaggtac ttctctctcc ttcctccttc     5280

tcctccacag tcacaagtaa ccaaggaacc tgaaagtgga tgtgtagcta tttgaagaag     5340

gcaaggaacc ctgagattct tctttgaatc ctctagtcca agtcttagac cagtgattgg     5400

tgcttacctt gaacaaaatt ttgtctgtgt tcctaatccc ttcaatactc tgggtacaat     5460

gctcccaatc accctgcaca tttgattcta aatggctttt attttttaaa aatccatatc     5520

cctaggacaa gagaacagga tgcctatatc cccaaaatga gctccaggac actgatggga     5580

atgatcccaa agatcacccc acctcagaaa cgtctgtgcc aagagacttc cccagataga     5640

aacactggga cagtggtttg aacgacttct tttatggttg tccagtttgc tatggaaata     5700

aaaggcattg attttttaaa aagatgattg gaacctgtct ttggccacat agggccactt     5760

ggatccattt ccaggcctta ctcatatatt gccttcactg aagggctttg gctttaagtc     5820

ccagactggt ctcccaagtg aaccataagt gttttggagc tcatctgggg tgaggcatga     5880

gaatgttgcc ccatctatcc cttcaggaaa aggtgccttc cctccctttc tcctaaagcc     5940

tggtccccag aaattgtttt tgtctccaaa agtctagtat ggtctttata cacccagact     6000

cttagtgttg cgtcctgcct tgtttccttg ttaaggatct atgcagacct cccgctttgg     6060

cttagctagc gtgacattgg ctatcatttg acaagactaa cttttttttt tttttttttt     6120

tgactgagtc tccctctgtc acctaggctg gagtgcagtg gcacaatctt ggctcgctgc     6180

aaccttcacc cttcacctcc caggtcgaag cgattctcct gcctcagtct cccgagtagc     6240

tgggattaca ggcgtgcgcc accaaatctg gctatttttt tattattatt atttttagta     6300

gagatggggt ttcaccatgt tggccagact ggtcttgaac tcttggcctc aaattatctg     6360

cccacctcgg cctcccaaag tgctgggatt acaggcatga gccaccatgc ccagctgaca     6420

agactaattt tttatccctt ggtttattgg cttcaacatc ttctggaatc agaggtgatt     6480

ttttcttacc ttggatgcct gagactaggg gagtatagaa ttccaattgg taattaaggc     6540

atctttctgc tcctgatcag aagggcaggt tagttgggag aggtcagatg gcacaacaga     6600

agtcaccttg taagtaaggc aaagacttga aggcattagc gtttctcatt actaggtcaa     6660

taacctgagg gaatcaatgg ctttttgccg ctctacctct tgtgtatctc tttgactttt     6720

ctttctctgt ctagtttcct ctgttctcag tttatattct atgttatcag tctctctttc     6780

cacagtacaa acatccatcc tttctcctgt gcaattctgt ctctccctct tattatcttt     6840

atttgtactt tttccttcct ccctgtctag gcattgggca tgtgcctctt cttagcctgt     6900

gattttgcct tgggactgat gataaattat ttccagattc aatcagccct ggtcctaccc     6960

cagtccaatc agaagtatgt tggtgggaat caacctgatc ctggcccttt cttcttctcc     7020

attttcattc gtaatccccc tcagcagatc tttacaagca gtttccttat agctcatgta     7080

tctttaggtc tttgccttcc aagcactgta cagaatactt tgtggttcct ttttagtctg     7140

acattttgtg gagcagtgaa gcgtgctcag agacataatc agctgaagag aaaaaatcca     7200

cccatggatt tatatcagct aaatactaat aattgatttt gtttgatgtg cccataattt     7260

ttaaagctgc aatataatat aatgagggac cacaggtaat ttctcctgtc atttgttttg     7320

gctggatggg ggtgggggag taattgctta aagttttacc attacacatt aaactctcta     7380

taataatctt gtttggggct tgctaactgt tgagctgttt taactaaact ggtaggcaat     7440

cggagttgat ttaaatgaaa agataattta acaaatctat actataaaaa gagacatttg     7500

cttaattgac atgtattttt tccttctgag tcacctaaac atttactctt gacaccaact     7560

gttcatgata ctgaatagac agtccatata agagaaatta gtggacctaa agaagccaga     7620

ttgtaggtgt taatttatta aacagagtgc aaagcccttg gaaatgtcac tgcttggcaa     7680

taccatatgg aatgccaaaa tttacaatga cttttcttta taagttatcc aaaagggatt     7740

tgaacaagta agaggttatg ccaaaatgtc tccaatgtat ggtcctgtaa tatattgcag     7800

cttgaagcca atgatccctt atgacttgta tacaactaat gcatgtttta ttgaattttg     7860

catttcccac gtgtggtaag ttctttaaaa tgtttttgat cacctttttg tgccattaaa     7920

cttgtacaga aaatgttttt atggccattt tcaaagggag aaagtttaaa atggaaacag     7980

cccacccttt ctgccctata gctgtagtta gaattgagta cctgtagcaa aacagctgta     8040

attggtggtt gtagtgttag aggtgttagc ttgctagtga ctagctttgg agagtaaatg     8100

catggtattg tacatcacat ttcttaactc gttttaacct ctgaaaagaa tatattcttc     8160

tttgtagtcc ttcttcccac ccccttgccc tctccctctc cctgctccca gttgtcttac     8220

agttgtaaat atctgatttg aggcccaata actcttgcca agtaaagtca gcaaacaaca     8280

aacaaaccaa aatgtgggga aaaggcattt ctcaaccatc tctcagcagt tattgatcat     8340

ttcttaagga acagcattgt gatcaaagac tcaactttac gtaaaaatca gtggtaaatt     8400

ggggttgtat ttggccattt gattacattt caggattgaa tagttttcag aatcacatgt     8460

aatccaaaga cagtaggtag tgatgtccct tatccctgca gctgttttaa gatagagacc     8520

tcagaagact ctgcttgacc gatgaccaat aattatttga aaaaaaaaga aaaaatgaga     8580

gaaataaaac agatatttaa gaactttagc cacctattta gaatagttat agccagaaaa     8640

aaaaacaagg gcatgagttc aaatgcatta ctatcagtgt cctaggcaat acctaaccta     8700

ctctgaaatt gtgattcaaa agcagtattt caagaggcat tctccttttt tggtttgctg     8760

accccacttg gactggtagg tttggtgagg cccccataaa ccagctggag cagacccttt     8820

tcatctcctg tgcctgtaac acccctcttc ccccaccccc tccgcaattc aatgagggct     8880

ttcttgggtc agaggacttc aaggttgtct agagaagttt gccatgtgtg taaggtgctg     8940

tgaactgtga gtgctgaaga ttcgcagcat tcaataccag gcagccaaag agctgctctt     9000

gcaattattt tggctctcaa gctctgttct tcatcgcatt ctcatttctg tgtacatttg     9060

caagatgtgt gtaatgtcat tttccaaaaa taaaatttga tttcaataaa aaaaaaaaaa     9120

aaaaaaaaaa aaaaa                                                      9135


<210>  1535
<211>  3594
<212>  DNA
<213>  homo sapiens

<400>  1535
ctttcttctc tctctgtttc tctcttgtgt ctttttgtcc ttatcttggt ctctctgctt       60

ctatttctac ctctctcagc gtgtgcgtct ctctttccct gtatgtctct gtctttctcc      120

gagtctctct tcttctcccc gcccccctca ctcccctttc tccgtccctc tctgtctctg      180

cgcctttctc gccctcactt tctcccctcc tgcctgctcc gggcctgccc ccaccgccgc      240

cggttcaggg gaacgtgtgc ggagcgattg tcctggggga catttgatgg attagagcgc      300

cgagcggttc cattgctagg ggaccacctg atctccagcc tgcgtcccat ataaagccgg      360

cagccggagt gctgagcgca gctcccgcga tcccctgtct gcgcgccgcc gccgccaagc      420

ccgagcccga gccggggccg ccgccaccgg tgccggctcc gagcggcctc ccgcgctcca      480

gcccgctggg agctgtccag tgctgaaaac ccgcgcggac acagccgatc gcgcccggcc      540

ggccgcctcc ccgcaccgag ccccgcgccg gccgcgccat gccgcgctcc ttcctggtaa      600

agaagatcaa aggggacggc ttccagtgca gcggggtgcc ggcccccacc taccacccct      660

tggagacagc ctacgtgctg cctggcgccc gggggcctcc cggggacaac gggtacgccc      720

cgcaccgcct gcccccgagc agctacgatg cggaccagaa gccgggcctg gagctggccc      780

cggccgagcc cgcgtacccg ccggcggcgc cggaggagta cagcgacccc gaaagcccgc      840

agtcgagcct gtcggcgcgc tacttccgag gggaggcggc agtgaccgac agctactcca      900

tggacgcctt cttcatctcg gacgggcgct cgcggcggcg gcggggcggg ggcggcgggg      960

acgcgggggg ctcgggagac gcggggggcg ccggggggcg cgcggggcgc gcgggggcgc     1020

aggcgggcgg cgggcaccgg cacgcgtgcg ccgagtgcgg caagacctac gccacgtcgt     1080

cgaacctgag ccgccacaag cagacgcacc gcagcctgga cagccagctg gcgcgcaaat     1140

gcccgacgtg cggcaaggcc tacgtgtcca tgcccgcgct cgccatgcac ctgctcacgc     1200

acaacctgcg ccacaagtgc ggcgtctgcg gcaaggcctt ctcgcggccc tggctgctgc     1260

agggtcacat gcgctcgcac accggcgaaa agccgttcgg ctgcgcgcac tgcggcaagg     1320

ccttcgccga ccgctccaac ctgcgcgcgc acatgcagac gcactcggcc ttcaagcact     1380

accgctgccg ccagtgcgac aagagcttcg cgctcaagtc ctacctccac aagcactgcg     1440

aggcggcctg cgccaaggcg gccgagccac ccccgccgac ccccgccggc ccggccagct     1500

gagccttccg cctcgccctc gcgcccggaa ctcgctctcc acgcgccccg ggccccctac     1560

ctgcgcccgc agcgccctcg cccagccccg gctgcgtttc cctgcccatg accctctcgt     1620

ggggaccccc ggcccggccc ggaacttttc tccccaaccc ccaaacccac gactcacttc     1680

cacaccgtct tccccagcgt cccccgaccc acttcatcct ttccggccat ccctcggacc     1740

ttgacccccc tgtccgcgcc ttcaaggctc ccaactcagg caccaggtcc gcacctctcc     1800

cgcgccccag agccggaaat ttctccctcc cagaccccgc gctgctcttc taacttctag     1860

atcttttctc tcgcttctca gctgaatctc tctgaccatt cctctactgg agcccccaat     1920

gaaagccgca aacctatacc cttgacgccc atacctgcct cagtttcccc atccacacct     1980

ggacgcaggc cctgccgccc tgagaccaca gtccaacccc agaccatccc tctggcctct     2040

gctgaatctc ccagagtgtg tccatctggg gatctaatct tcacccttct tgaagtctcc     2100

gatctgtccc tgatcccatc catgctcagg ccttaggtct ggccattcac acacacacac     2160

acccccacac cccactccca cacacagttc ctactgtctt cagtccatgg ggatctcatc     2220

acccactccc agccccagct ccagctgccc tcacctctct agcagctctc acccctctga     2280

gtctacctaa cctggagggg gcttgagggg cacttcaggg ccctgccccc taatgtaacc     2340

cctctctcac cccggcacaa cctgggcttc cacagtctgg agctgcccta cccccagatt     2400

ctctgagcac tttcccccat ccccagggcc acagatcccc ttccttactt gttgggggga     2460

ggtctggagc acctcgccaa tgcccttccc ccatccggct gggtccttcc agttatttat     2520

ttgtgtattt atttatttat ctatttatta ttctatttaa tctcttggcc tcacccaggg     2580

accgtctggc ttccccagct ggactgggag gtcaggaagc caggcaagga gagggacagc     2640

acaggccaca gagggctgcc cccaccacac acacccccgc gtctcgggag aaacccaccc     2700

tcttcagagc ctgcactcgc taaggaaggg gactcgagaa tgggggggca gcttgctgac     2760

cctcaactgg gggggtgagg gagcatcagg aggtccaggc gtggggcagg tccccacctt     2820

cctgaacctt cccctgccac tccaggcggc ccggagagag gagcctcttc gatttgtttc     2880

ctgtttattc ttcttcccga gggaccccag gttccaggga ccgactgagc cccggacccg     2940

ctggggcctc tggcctgctc cccgggaggg gcgctctctc ccggccatgt ctatgcaact     3000

ctcccggaca gaggggccgg gctgccagcc acccgcccgt tggccgccac tacctcctcc     3060

gctgcgcttt tgcatgcccg ggcgaggacc gaagcacaca cctccacgcg cacgggccct     3120

ggccccctcc gctttaagca cacgcctctg ccccattgct ctgcagccag cttgggggca     3180

ggagtcctgg actctcagat cctcctctcc cctcctctta gccacaaaag aggggggaga     3240

ctggaggcac ccctgcagca ggggcacttc cctagggctc cagaggggtg aatgggcctt     3300

tgctcagctc caggcccagc gggaagggag gctgcaggga tggtgggagg gagaggggta     3360

gcagaagcaa ttatggaggc gttgaccctg taaatagcaa cttctgacag caataatttt     3420

ccatgcatgc taagcctttt ggccatattt tgtatgagcg cttggcgctc ctcctccgtc     3480

ctatcccaac tcacccccaa acccccatcc cttccccacc tccagcagta ttacttgtaa     3540

cgcaattcag ggatattaaa gggactttgg ccactcaaaa aaaaaaaaaa aaaa           3594


<210>  1536
<211>  1870
<212>  DNA
<213>  homo sapiens

<400>  1536
ctccgagacg ggtggggccg gagctccaag ctggtttgaa caagccctgg gcatgtttgg       60

cgggaagttg gcttagctcg gctacctgtg gccccgcagt tttgtagtcc ccgccttgtt      120

tctccccaga ggcctctcaa tcctccctcc atgatcttcg catagagcac agtacccctt      180

cacacggagg acgcgatggc tcccaagaaa cgcccagaaa cccagaagac ctccgagatt      240

gtattacgcc ccaggaacaa gaggagcagg agtcccctgg agctggagcc cgaggccaag      300

aagctctgtg cgaagggctc cggtcctagc agaagatgtg actcagactg cctctgggtg      360

gggctggctg gcccacagat cctgccacca tgccgcagca tcgtcaggac cctccaccag      420

cataagctgg gcagagcttc ctggccatct gtccagcagg ggctccagca gtcctttttg      480

cacactctgg attcttaccg gatattacaa aaggctgccc cctttgacag gagggctaca      540

tccttggcgt ggcacccaac tcaccccagc accgtggctg tgggttccaa agggggagat      600

atcatgctct ggaattttgg catcaaggac aaacccacct tcatcaaagg gattggagct      660

ggagggagca tcactgggct gaagtttaac cctctcaata ccaaccagtt ttacgcctcc      720

tcaatggagg gaacaactag gctgcaagac tttaaaggca acattctacg agtttttgcc      780

agctcagaca ccatcaacat ctggttttgt agcctggatg tgtctgctag tagccgaatg      840

gtggtcacag gagacaacgt ggggaacgtg atcctgctga acatggacgg caaagagctt      900

tggaatctca gaatgcacaa aaagaaagtg acgcatgtgg ccctgaaccc atgctgtgat      960

tggttcctgg ccacagcctc cgtagatcaa acagtgaaaa tttgggacct gcgccaggtt     1020

agagggaaag ccagcttcct ctactcgctg ccgcacaggc atcctgtcaa cgcagcttgt     1080

ttcagtcccg atggagcccg gctcctgacc acggaccaga agagcgagat ccgagtttac     1140

tctgcttccc agtgggactg ccccctgggc ctgatcccgc accctcaccg tcacttccag     1200

cacctcacac ccatcaaggc agcctggcat cctcgctaca acctcattgt tgtgggccga     1260

tacccagatc ctaatttcaa aagttgtacc ccttatgaat tgaggacgat cgacgtgttc     1320

gatggaaact cagggaagat gatgtgtcag ctctatgacc cagaatcttc tggcatcagt     1380

tcgcttaatg aattcaatcc catgggggac acgctggcct ctgcaatggg ttaccacatt     1440

ctcatctgga gccaggagga agccaggaca cggaagtgag agacactaaa gaaggtgtgg     1500

gccagacaag gccttggagc ccacacatgg gatcaagtcc tgcaagcaga ggtggcgatt     1560

tgttaaaggg ccaaaagtat ccaaggttag ggttggagca ggggtgctgg gacctggggc     1620

actgtgggac tgggacactt ttatgttaat gctctggact tgcctccaga gactgctcca     1680

gagttggtga cacagctgtc ccaagggccc ctctgtatct agcctggaac caaggttatc     1740

ttggaactaa atgacttttc tcctctcagt gggtggtagc agagggatca agcagttatt     1800

tgatttgtgc tcacttttga tatggccaat aaaaccatac cgactgagaa aaaaaaaaaa     1860

aaaaaaaaaa                                                            1870


<210>  1537
<211>  1752
<212>  DNA
<213>  homo sapiens

<400>  1537
agggcgcagc aggccaaggg ggaggtgcga gcgtggacct gggacgggtc tgggcggctc       60

tcggtggttg gcacgggttc gcacacccat tcaagcggca ggacgcactt gtcttagcag      120

ttctcgctga ccgcgctagc tgcggcttct acgctccggc actctgagtt catcagcaaa      180

cgccctggcg tctgtcctca ccatgcctag cctttgggac cgcttctcgt cgtcgtccac      240

ctcctcttcg ccctcgtcct tgccccgaac tcccacccca gatcggccgc cgcgctcagc      300

ctgggggtcg gcgacccggg aggaggggtt tgaccgctcc acgagcctgg agagctcgga      360

ctgcgagtcc ctggacagca gcaacagtgg cttcgggccg gaggaagaca cggcttacct      420

ggatggggtg tcgttgcccg acttcgagct gctcagtgac cctgaggatg aacacttgtg      480

tgccaacctg atgcagctgc tgcaggagag cctggcccag gcgcggctgg gctctcgacg      540

ccctgcgcgc ctgctgatgc ctagccagtt ggtaagccag gtgggcaaag aactactgcg      600

cctggcctac agcgagccgt gcggcctgcg gggggcgctg ctggacgtct gcgtggagca      660

gggcaagagc tgccacagcg tgggccagct ggcactcgac cccagcctgg tgcccacctt      720

ccagctgacc ctcgtgctgc gcctggactc acgactctgg cccaagatcc aggggctgtt      780

tagctccgcc aactctccct tcctccctgg cttcagccag tccctgacgc tgagcactgg      840

cttccgagtc atcaagaaga agctgtacag ctcggaacag ctgctcattg aggagtgttg      900

aacttcaacc tgagggggcc gacagtgccc tccaagacag agacgactga acttttgggg      960

tggagactag aggcaggagc tgagggactg attcctgtgg ttggaaaact gaggcagcca     1020

cctaaggtgg aggtggggga atagtgtttc ccaggaagct cattgagttg tgtgcgggtg     1080

gctgtgcatt ggggacacat acccctcagt actgtagcat gaaacaaagg cttaggggcc     1140

aacaaggctt ccagctggat gtgtgtgtag catgtacctt attatttttg ttactgacag     1200

ttaacagtgg tgtgacatcc agagagcagc tgggctgctc ccgccccagc ccggcccagg     1260

gtgaaggaag aggcacgtgc tcctcagagc agccggaggg aggggggagg tcggaggtcg     1320

tggaggtggt ttgtgtatct tactggtctg aagggaccaa gtgtgtttgt tgtttgtttt     1380

gtatcttgtt tttctgatcg gagcatcact actgacctgt tgtaggcagc tatcttacag     1440

acgcatgaat gtaagagtag gaaggggtgg gtgtcaggga tcacttggga tctttgacac     1500

ttgaaaaatt acacctggca gctgcgttta agccttcccc catcgtgtac tgcagagttg     1560

agctggcagg ggaggggctg agagggtggg ggctggaacc cctccccggg aggagtgcca     1620

tctgggtctt ccatctagaa ctgtttacat gaagataaga tactcactgt tcatgaatac     1680

acttgatgtt caagtattaa gacctatgca atatttttta cttttctaat aaacatgttt     1740

gttaaaacag tt                                                         1752


<210>  1538
<211>  7735
<212>  DNA
<213>  homo sapiens

<400>  1538
ctctctcccg gcgaagctgg gaattgggtg ggattacacg gagcagcccc gccgccgccg       60

ctggcagagg ccggcttgga gagggcgggg gttcccctcc gtcagtcgcc cctggcgccc      120

ctcgcctcgt cgcactctcc gcctcgctct ccccgacgtc cggccaggag gagccggtag      180

catcgggagc ctcgcgccga gggcgccgcg gtccgcgccc cgcgactgca gcccccggcc      240

tggccccggc ggggcgcccc ctcccctccc cctcctgcga gctgggatcc ggccggcttc      300

cgccctcccc tggccgcgag accggccccg gcggctgggc cgccagtagc tccagccatg      360

ggctcggggc gcgtacccgg gctctgcctg cttgtcctgc tggtccacgc ccgcgccgcc      420

cagtacagca aagccgcgca agatgtggat gagtgtgtgg aggggactga caactgccac      480

atcgatgcta tctgccagaa caccccgagg tcatacaagt gcatctgcaa gtctggctac      540

acaggggacg gcaaacactg caaagacgtg gatgagtgcg agcgagagga taatgcaggt      600

tgtgtgcatg actgtgtcaa catccctggc aattaccggt gtacctgcta tgatggattc      660

cacctggcac atgacggaca caactgtctg gatgtggacg agtgtgccga gggcaacggc      720

ggctgtcagc agagctgtgt caacatgatg ggcagctatg agtgccactg ccgggaaggc      780

ttcttcctca gcgacaacca gcatacctgt atccagcggc cagaagaagg aatgaattgc      840

atgaacaaga accacggctg tgcccacatt tgccgggaga cacccaaggg gggtattgcc      900

tgtgaatgcc gtcctggctt tgagcttacc aagaaccaac gggactgtaa attgacatgc      960

aactatggta acggcggctg ccagcacacg tgtgatgaca cagagcaggg tccccggtgc     1020

ggctgccata tcaagtttgt gctccatacc gacgggaaga catgcatcga gacctgtgct     1080

gtcaacaacg ggggctgtga cagtaagtgc catgatgcag cgactggtgt ccactgcacc     1140

tgccctgtgg gcttcatgct gcagccagac aggaagacgt gcaaagatat agatgagtgc     1200

cgcttaaaca acgggggctg tgaccatatt tgccgcaaca cagtgggcag cttcgaatgc     1260

agttgcaaga aaggctataa gcttctcatc aatgagagga actgccagga tatagacgag     1320

tgttcctttg atcgaacctg tgaccacata tgtgtcaaca caccaggaag cttccagtgt     1380

ctctgccatc gtggctacct gttgtatggt atcacccact gtggggatgt ggatgaatgc     1440

agcatcaacc ggggaggttg ccgctttggc tgcatcaaca ctcctggcag ctaccagtgt     1500

acctgcccag caggccaggg tcggctgcac tggaatggca aagattgcac agagccactg     1560

aagtgtcagg gcagtcctgg ggcctcgaaa gccatgctca gctgcaaccg gtctggcaag     1620

aaggacacct gtgccctgac ctgtccctcc agggcccgat ttttgccaga gtctgagaat     1680

ggcttcacgg tgagctgtgg gacccccagc cccagggctg ctccagcccg agctggccac     1740

aatgggaaca gcaccaactc caaccactgc catgaggctg cagtgctgtc cattaaacaa     1800

cgggcctcct tcaagatcaa ggatgccaaa tgccgtttgc acctgcgaaa caaaggcaaa     1860

acagaggagg ctggcagaat cacagggcca ggtggtgccc cctgctctga atgccaggtc     1920

accttcatcc accttaagtg tgactcctct cggaagggca agggccgacg ggcccggacc     1980

cctccaggca aagaggtcac aaggctcacc ctggaactgg aggcagaggt cagagccgaa     2040

gaaaccacag ccagctgtgg gctgccctgc ctccgacagc gaatggaacg gcggctgaaa     2100

ggatccctga agatgctcag aaagtccatc aaccaggacc gcttcctgct gcgcctggca     2160

ggccttgatt atgagctggc ccacaagccg ggcctggtag ccggggagcg agcagagccg     2220

atggagtcct gtaggcccgg gcagcaccgt gctgggacca agtgtgtcag ctgcccgcag     2280

ggaacgtatt accacggcca gacggagcag tgtgtgccat gcccagcggg caccttccag     2340

gagagagaag ggcagctctc ctgcgacctt tgccctggga gtgatgccca cgggcctctt     2400

ggagccacca acgtcaccac gtgtgcaggt cagtgcccac ctggccaaca ctctgtagat     2460

gggttcaagc cctgtcagcc atgcccacgt ggcacctacc aacctgaagc aggacggacc     2520

ctatgcttcc cttgtggtgg gggcctcacc accaagcatg aaggggccat ttccttccaa     2580

gactgtgaca ccaaagtcca gtgctcccca gggcactact acaacaccag catccaccgc     2640

tgtattcgct gtgccatggg ctcctatcag cccgacttcc gtcagaactt ctgcagccgc     2700

tgtccaggaa acacaagcac agactttgat ggctctacca gtgtggccca atgcaagaat     2760

cgtcagtgtg gtggggagct gggtgagttc actggctata ttgagtcccc caactacccg     2820

ggcaactacc cagctggtgt ggagtgcatc tggaacatca accccccacc caagcgcaag     2880

atccttatcg tggtaccaga gatcttcctg ccatctgagg atgagtgtgg ggacgtcctc     2940

gtcatgagaa agaactcatc cccatcctcc attaccactt atgagacctg ccagacctac     3000

gagcgtccca ttgccttcac tgcccgttcc aggaagctct ggatcaactt caagacaagc     3060

gaggccaaca gcgcccgtgg cttccagatt ccctatgtta cctatgatga ggactatgag     3120

cagctggtag aagacattgt gcgagatggc cggctctatg cctctgaaaa ccaccaggag     3180

attttaaagg acaagaagct catcaaggcc ttctttgagg tgctagccca cccccagaac     3240

tacttcaagt acacagagaa acacaaggag atgctgccaa aatccttcat caagctgctc     3300

cgctccaaag tttccagctt cctgaggccc tacaaatagt aaccctaggc tcagagaccc     3360

aattttttaa gcccccagac tccttagccc tcagagccgg cagcccccta ccctcagaca     3420

aggaactctc tcctctcttt ttggagggaa aaaaaaaata tcactacaca aaccaggcac     3480

tctccctttc tgtctttcta gtttcctttc cttgtctctc tctgcctgcc tctctactgt     3540

tccccctttt ctaacacact acctagaaaa gccattcagt actggctcta gtccccgtga     3600

gatgtaaaga aacagtacag ccccttccac tgcccatttt accagctcac attcccgacc     3660

ccatcagctt ggaagggtgc tagaggccca tcaaggaagt gggtctggtg ggaaacgggg     3720

aggggaaaga agggcttctg ccattatagg gttgtgcctt gctagtcagg ggccaaaatg     3780

tcccctggct ctgctcccta gggtgattct aacagcccag ggtcctgcca aagaagcctt     3840

tgatttacag gcttaatgcc agcaccagtc ctctggggca catggtttga gctctggact     3900

tcccacatgg ccagctttct tgtctataca gatcctctct ttctttccct acgtctgcct     3960

ggggtctact ccataagggt ttacaaatgg cccacaacac tgagttagtg gacaccggct     4020

aaatgaggaa gagcagcagg cattgtcatg gtgaatgccc cgctgtagct ccctgagaga     4080

aagactgtaa ctctgcagga cagaaacaag gttttaaagc attgccaaaa aaaagaaaac     4140

agaaagaaaa aatgtatcat ctaaaggact agacacagaa caattggaag tcaacttcaa     4200

acactaatcc cttttcttgt cttccctggc ccagccacct cctcagcccc atgtgatgct     4260

ccctggggga gccctactcc ccttgctaca tgttgtcctt aaacatggtt attgacctga     4320

agccagccta ggccttgccc tacagttgtt tttcccttgt agccccagct ggcttgtggg     4380

cttcaccaaa gaggacccca ctctgaagcc agcctggagc cacctacctc tggcctcagg     4440

ctgtgggcag caaaaggaat gtgtgtgcac ttggcgagcc tcctgcccac cctgtccaca     4500

cctaataagt gcaatcattt tgagtctttc tatgttgtct agacggaggg gtttttgttt     4560

tctgggtttg ttttttgttt ttgtttcttc ttcctctatt agcaaaaccc tatttatagc     4620

tgcccaagag aaaagagtgt atgtttggag tggaagaaaa tcggttttga atctcatgaa     4680

ccttgagtgc tggagcatct gatctgtctc tatgccacca ctggccacct agagcccttg     4740

gctgtggtaa tccagggtaa ttgcgcagag gcatctgatg tgtaggaaag taattctggg     4800

gatttgatgg agcagaaagg agagagacct atgtttgcta aaccaatctt gctatcccta     4860

tgcctctcca tggagtcagt gtggacctca tgattataga ggccaatgga actggtcagt     4920

gattctctac cccaagtagg gaaaacctcc atcttttccc tgtcttcatc ctgttatccc     4980

ctggtgtaca catggaagag gaccaggaca taccacctgg ggatgggctg actcagggtc     5040

ccgaggccag agacaaagct gtgggagcca agaataagac agaaggcatc agatatttgc     5100

ctggctctgg tcacttccct ttgaagttga cttcaagctt agcttcctca actactgttt     5160

ttcagaagga agaaagaatc aaatggaaga agaatcaagt ccatgcccaa gcccaaagcc     5220

tgcacacatt ctgcccttaa tccaagtgtt gcctataaaa ttattttctg ttttctcact     5280

ctagttcccc caaagctgta gtcccaatca atcaaaggct accaactgag tcctcaggtt     5340

catttctttt tttttttttt ttctttttaa ctctcctggt aactcacaga acagctcagg     5400

ttcatttcta ggtgactgtc ctaggctact gctcccccag gagactcaac actaaataaa     5460

ggagtctgac tccctgccct cccatcagta gcattcatca gccaaaacgg ccatagcagt     5520

aggtagccaa tgacacagct agattccctg acaaccatta gccaacatca tggtccttgt     5580

gggtagagtg tctggctacc tttgtctttc tgggtcaagg agggccactg taaagatgca     5640

aaatggctgc ttccaaacaa gggaaatggt catttagtat gagtgtctct gtacttccca     5700

ggaagcacca tgaaaactgc tttaatcaac tctgactatc ctaattctcc accagaagct     5760

aggataactt tctttctttc tttctttttt tttttttttt tttttgagat ggagtctcgc     5820

tctgtcaccc aggctggagt gtaatggtgc tatctcggcc tactgcaacc tccgcctccc     5880

aggctcaagc aattctgcct cggcctccca agtagctggg attacaggca tgcgccaccg     5940

cgcccagcta atttttgtat ttttagtaga gatggggttt caccatgttg cccgggctgg     6000

tcttgaactc ttgacctcag gtgatccacc cgcctcagtc tcccaaagtg ctgggattac     6060

aggcatgagc caccgcgccc agcctaggat aactttctga ttcctctctg ccagccgttt     6120

tgcgtctctt ggaaagccaa acggtgacca tgcttcttaa tttatgcctt cagggtctgg     6180

cttctccttt ctcccttcct ttcctgtcac accatgcata catacataca aatacacatc     6240

cttcaaccat ttattccatg gcttatgaga cctgcaaatg agttccacag tacggaaggc     6300

atagaccact aggcttctta attgatgtca aggcagatct tggtgagcag gtaaaaacct     6360

gctattgtcc accaagttta atttaggtcc tccaagttgg agggttaaga acccaggcaa     6420

agctgctgct gaatctatgg aggaggctgg ccctgggaca tcaaactagg ggttaactgg     6480

attgaatgag gagtcaacgc tcagggacat tctaggtctt tacaggtcag acagaagaga     6540

ggtttttacc attggaggga aatggaaaga tggtataaat aggatccctt catgaagcaa     6600

cccagaggcc tctctgcagc gtgtagggtg tggggcgaca gtattgtggg gcttccattc     6660

atcttagtac aaaacctcac ctgctctgag cctggaaatg ggagggcttc acgcaccaag     6720

taatgcacac cagaaaggca cttatatcct cagcaacatg gcagttcctc tttacttctc     6780

tgcctccctc tttctatatt atcaggccat gcctattcct acaacctgag acaactcttg     6840

gagtcagaag aaaactgacc agatcctgga tctgagctgc ctgctccagg cctagaaatc     6900

cccaaaggct ggcactgagc tgtgactgct ttaacagccc ccaagatttg gtcagtttga     6960

ggtggtggag actcagattt gttgctgaaa gttcagtaac acagtcctgg tctttggccc     7020

tagagaaact ttttatatga gaagtgttct ctatatacat gtttgaggtg actctggaat     7080

ggattatgag gtcatatctc aaaatgtcag aaaacgttat agagcactcg aacttttgta     7140

tttgctgctt aacctcaata ttacagccac aaacaagggg taccaagaca aagtataact     7200

gagcataagc agaaaatgtt aaccctccag gtttctttct taagcacaat aaaagtggga     7260

gcgaacaaca caaggatatt tttacatttg acccgtctca aaagtagcac accctatcct     7320

tgtgccatta tttgtacaag gaaatatatg attagaagga atagaacccc cagttgtcat     7380

cagctttttt agacaccaca ggttgtagca gtttgaacaa actgaaaact ttatacttct     7440

gtgtgagctg aactcaagtt tcagaataat catcgccatg tgggaggctt tttgttaaat     7500

gcagaagaaa tttcaaaata ttgtatttat atctgccttc cactgctgcc aatttagtaa     7560

gcatctccta tacaatcgac aataaacagc aaatgatgca gttcatagag tattttgcac     7620

ttggggaaaa atatgtatct gaattgtaaa aagaaatgtt tggattttgt atgtcttttt     7680

tattattatt aaaatactaa atgaaactcc tcaaaaaaaa aaaaaaaaaa aaaaa          7735


<210>  1539
<211>  3289
<212>  DNA
<213>  homo sapiens

<400>  1539
cgcggagcgg aggccgaggc gagagcctgg cgctgtagga ctagaacgaa aggagtgagg       60

cgccgagagc ccagatacca ttttggcgtg agagctggtg gttggcaagg ccgcgggagt      120

gggaagcgtc cgccatgttc tgcgaaaaag ccatggaact gatccgcgag ctgcatcgcg      180

cgcccgaagg gcaactgcct gccttcaacg aggatggact cagacaagtt ctggaggaga      240

tgaaagcttt gtatgaacaa aaccagtctg atgtgaatga agcaaagtca ggtggacgaa      300

gtgatttgat accaactatc aaatttcgac actgttctct gttaagaaat cgacgctgca      360

ctgtagcata cctgtatgac cgcttgcttc ggatcagagc actcagatgg gaatatggta      420

gcgtcttgcc aaatgcatta cgatttcaca tggctgctga agaaatggag tggtttaata      480

attataaaag atctcttgct acttatatga ggtcactggg aggagatgaa ggtttggaca      540

ttacacagga tatgaaacca ccaaaaagcc tatatattga agtccggtgt ctaaaagact      600

atggagaatt tgaagttgat gatggcactt cagtcctatt aaaaaaaaat agccagcact      660

ttttacctcg atggaaatgt gagcagctga tcagacaagg agtcctggag cacatcctgt      720

catgaccatg cgccgaggca cttccaggct tcactcaact catggactcc tctgtactca      780

ctctctccac cactcccttc acctccctct ttgattttag aagctataga cattgtttaa      840

gataactaag aatacttggc taagaagtat aatttgctaa ctattaagga ctttcttttt      900

ttaatgttgt acactattct tcctactctt ttttggtttt ggttttgttt tgtagagact      960

gtctcactat gttgcccaag ctggtctcaa actcctggcc tcaagcagtc ctcccacctt     1020

agcttctcaa agtgttgaga tcacaggcgt gagccactgc acccggcccc tactcctttt     1080

tctaataagc tgtatctgta atcacagcat tcctacagtt gttacagtgt gttttttaaa     1140

tgaaagtaaa catggttaca tttgaatctc ttaaataagc agtcacttgg ctggacagga     1200

agaaggtaga tcctgtgtgt cttgttttct ggtcatgtgt attgtacaag ctagagagct     1260

gaatttctga gatacacatt ttcaaatcac atgcaagtga agatgatggt ctgtagaaat     1320

tttcagtata tataatgttt aatgacatac taatttatca tctggctatt tgggaaggaa     1380

ggacacacat ggattttgca catttccacc atggtggctg gtgtggcttg tggctatggg     1440

gtgatcacca gtatcaccac tttggaaggg gacagtgaaa ttggggctag agaaggaact     1500

ttgtacagtt ttccctgaga ttcagattga ctgaaaagtc acatgaagag ttgattgtct     1560

tttaatggta tgttttaaac agctgacatt ttaaattttg atgaaatcca gtttattcgt     1620

ttgttctttt atgctttggg tgttgcatcc gagaaatctt ttcccatccc aagatcacaa     1680

ttttttttcc tttttacttc tagaagtgtt ataattttaa gctttatact ttggtctatg     1740

acccgttttt ttttttgttt tgttttgttt tttcgtttgt ttctttgttt tgagatggag     1800

tcttgttctg tcacccaggc tggggtgcag tggcgtgatc ttggctcact gcaatctcta     1860

tcccctgggt tcaagtgatt ctcttgtctc agcctcccaa gtagctggga ttacaggcac     1920

aggccgccac gcctggctaa tttttgtatt tttagtagag acagagtttt accatgttgg     1980

ccaggctggt ttcaaactcc tgacctcaag tgacccacct tggcctccca aagttttggg     2040

attacaagtg tgggccaccg cggccagcct atgatccatt ttgaatgaat tttttatatg     2100

gtgcaaggtg tcaatccacc ttcacttttt cttgggaata tagatatcca gctgtttcac     2160

taccattttt tgaaaggact gccctttgct ctatcacctt tgcatttttg ttaaaaagta     2220

gttgtcaatg tatatgtggg tttatttcag gactctgttt tgttccattg acctgttttt     2280

ctctcctgaa tgccaatacc atatttgtat gtagtgtatg taattttcta ataattcttg     2340

aaacagatag tattaatgtg tcatattttt gctgttgttt gtattttttg tagagatggg     2400

gtttcaccgt gttggccagg ctgtgttgaa ctcctgagct aaagcaatac acttgcctcg     2460

tcctccccat gtgctgggat tacaggcgtg agccttggtg ctggcccagt gtaccacatt     2520

tctttttgag atttgttttg gctatgttaa gtcctttgct tttgatgtga aatttgggaa     2580

caggcagggt gtggtggctt atgcctgtaa tcctagaact ttgggaggcc tagatgggtg     2640

gatcacttga gctcaggagt tccagaccag cccgggccta tggcaaaact ccgtctctac     2700

aaaaaataga aaaaattagc caggtgtggt ggtgcatgcc tgtagtcaca gttacacggc     2760

aggctgaggt gggaggatca cttgaacccc agaggtcaag actgcagtga gctgagatca     2820

caccactgta ctccagcctg ggtgacaaag tgagactcta tctcaaaaag aaattaggat     2880

caatttgtca atttctacaa caacaacaac aaaaacccct gttgggcacc ttgattgaga     2940

ttgcattgaa tttatataaa actgttggga gaattgacat cttaataata ttgagtcttc     3000

tggcctataa acaaggtctg tcttcctagg tattaatgtt ttgtcttcta tttctcttaa     3060

taatcttttg tagttttcag tgtacaggtc taccatgtca gcatttcata gttttgatgc     3120

taaatggtat tttaaaattt caaattctaa ccacttgttg ctagtaaata gaaatacaat     3180

tgatgttgaa cttgtatcct tcagccttgc taaactgtga gttctcatgg tgtttttgta     3240

aattacatca acagtcatgt gttctatgaa taaagagttt tactccttc                 3289


<210>  1540
<211>  1319
<212>  DNA
<213>  homo sapiens

<400>  1540
cgcgcttggc cttgcccgcg cccgctcgcc tcgtctcgcc cggcctcccc gcgtcgcctc       60

gtcgcctgtt ccgcgccagg catggccccc agcactgtgg ccgtggagct gctcagcccc      120

aaagagaaaa accgactgcg gaagccggtg gtggagaaga tgcgccgcga ccgcatcaac      180

agcagcatcg agcagctgaa gctgctgctg gagcaggagt tcgcgcggca ccagcccaac      240

tccaagctgg agaaggccga catcctggag atggctgtca gctacctgaa gcacagcaaa      300

gccttcgtcg ccgccgccgg ccccaagagc ctgcaccagg actacagcga aggctactcg      360

tggtgcctgc aggaggccgt gcagttcctg acgctccacg ccgccagcga cacgcagatg      420

aagctgctgt accacttcca gcggcccccg gccgcgcccg ccgcgcccgc caaggagccc      480

aaggcgccgg gcgccgcgcc cccgcccgcg ctctccgcca aggccaccgc cgccgccgcc      540

gccgcgcacc agcccgcctg cggcctctgg cggccctggt gacccggcgg gacctgcggg      600

cgcgcggccc gacgaccaga gggcgagcct gctcctctcg cctgtaggga agcgccttcc      660

cgccgtcgtc cgccccgggc ttggacgcgc ccttctccgg aaggctctgg ccccaagctg      720

gccggcccgc aggagcccca ttctcagaga atgtgtgtgc agagtccctg ccgttttagg      780

acaatcaggg cccatcttct gccaagtgtc tgaccccatg gggttgttct gtgtttgcat      840

ttaagcaagt gacttctggg aagtccccgg ccgcccgggg ttctatgata tttgtagtgc      900

cggggctcgc acactgctgc ccccagcctg tagaggactt tcttcagggc ccgtagctgc      960

tgggcgtacc cctggcaggc gggctgtgcc gcgggcacat ttgccttttg tgaaggccga     1020

actcgagctg tatcctcata ggaaacagtg atcaccccgg acgggcgtcc aggaccctga     1080

gggccatggc caaaaggctc ctgagtgtgc ctggtggtct ggctggggct cacggtgggc     1140

tgtctgggga gggtgggtgc ctccactatg atccttaaag gattcctctg tgtgggtgga     1200

tgcgtgtggg cacgactttg tactcagaaa ttgaactctc agtcacgtgg aagccacggg     1260

actgctccga agccgccata ataaaatctg attgttcagc ccccaaaaaa aaaaaaaaa      1319


<210>  1541
<211>  3947
<212>  DNA
<213>  homo sapiens

<400>  1541
gctcttcttc cttccttctc cagtcccttc cactgtgcgt cttctgtccc ccgttcttcc       60

ccagcggacc cctctttcga gactccctag tggggtcccc agctcccggg cgatcctgcc      120

cttgccgagc gcgttttctg gagtcacctg ggggagggga gtcctgggca gggccgggct      180

ggggaagacg cctggggcac tgcccggcgt taacaaaggg agccgatacc gaccggcgtg      240

ggcgcggagc gggcggccgc caccgagcgt gctgagcaac cgcagcctcc gcggccgaga      300

gtgcagcgag caaggggaga gccagttgcg cagagccctg caaccagcag tccagggaga      360

agtggtgaat gtcatggagc ccagctgaaa tggactggcc cccttgagcc tgtcccaagc      420

cctggtgcca ggtgtccatc cccgtgctga gatgagtttt gatcatcctg agaaaaatgg      480

gccttggcct gcagacccaa taaaccttcc ctcccatgga taatagtgct aattcctgag      540

gacctgaagg gcctgccgcc cctgggggat tagccagaag cagatgatca tgacgcagtc      600

ctgaggttta atggggcacc cacagccaac ttccaacaag atgtgggcac aaaaactacc      660

attcgcctga tgaactctca gttggttacc acagagaagc gcttcctcaa agacagtttg      720

tacaatgaag gaatcctaat tgtatgggac ccatctgtat accactcaga tatcccaaag      780

tggtaccaga atccggatta taatttcttt aacaactaca agacttatcg taagctgcac      840

cccaatcagc ccttttacat cctcaagccc cagatgcctt gggagctatg ggacattctt      900

caagaaatct ccccagaaga gattcagcca aaccccccat cctctgggat gcttggtatc      960

atcatcatga tgacgctgtg tgaccaggtg gatatttatg agttcctccc atccaagcgc     1020

aagactgacg tgtgctacta ctaccagaag ttcttcgata gtgcctgcac gatgggtgcc     1080

taccacccgc tgctctatga gaagaatttg gtgaagcatc tcaaccaggg cacagatgag     1140

gacatctacc tgcttggaaa agccacactg cctggcttcc ggaccattca ctgctaagca     1200

caggctcctc actcttctcc atcaggcatt aaatgaatgg tctcttggcc accccagcct     1260

gggaagaaca ttttcctgaa caattccagc ctgctccttt tactctaggg gcctctgtca     1320

gcaagaccat ggggacttca agagcctgtg gtcaggaaat caggtccagc cttccctgta     1380

gccagacagt ttatgagccc agagcctcct gccacacaca tgcacacata tctagcattc     1440

tttccagaca gcatcctccc cgccttccac cttggtagat gcaaggtcta tctctcccat     1500

cagggctgcc aaagctgggc tttgtttttc ccagcagaat gatgccattc tcacaaacca     1560

atgctctata ttgcttgaag tctgcatcta aatattgatt tcacgtttta aagaaattct     1620

cttaaattac aattgtgccc aatgcagggt ggctctgggg ggcaagtagg tggtacaggg     1680

gattggaaac atgctccgcg cctccagaga aaagttgctc ccgaggtcca tgcccctgga     1740

acgtgttcct atcactctgg ctggttgggc tggtccttag actgggtgct tatgattaaa     1800

gggtcttggt tagcccactt tccctctcca tgtggagatg gaaggtagag aaggatacag     1860

tgtctatcct caagttgcta cggttcagtg agagaggcag acatctgaac aggcaggtag     1920

gattcagtgt gctcagtgca ctggggattt ggagagagat gggcttgctc tctctgtgca     1980

cccaggaggg ccacgcactt aaaactgtgt ttgtggatca gagaaggctt tatagcacag     2040

ggggcattca gatgagtctt agaggaagag aagaaacatg gcaagcagat tacatctgag     2100

ccgtttgaat tgtgtttttc tttcttccca tgtttatttt ctaagatcta cctgaactta     2160

gagactcaag atattttttt aggaaacctc ctacccatgt ctgaggtagc aagtgcagcc     2220

tcacgacaga taccaggcaa tccagagcca caaaacgtga ttcctccagg ctctgcctgg     2280

cctgaccctg tcctgtcagc tgggtttaca taccagtccc attcttcctt ttcaatacct     2340

acccccaaat cttctcctaa ccaccatctg tttttttttt ttaaagcatt ttttgcttta     2400

aaagcatcct gaccccaatt tctttgagct cacgggcctt ttgctgaagg tctctcaggg     2460

tgtagtggtg tggctctctg gacttaacgt cactctcaga ggtcagaacc ttggagatca     2520

gaactgattc tcaccaggtg tgagaggtgt ggtagcagat tgcaatgctc tgcacctctt     2580

ccttgcaagt gagcaacttc aggctctctg ggcagaggct ggcccactgt agtttgcaga     2640

catgctctcc agatggtttt actaagtccc ctctccctga tagggaatcc tgctggacca     2700

gcgcagccct ggtgtggaga ggttaaaaga cttgcacagg atcaccaagt catgctgtag     2760

agccaggatt cctagaccca gggctctgca ctctcaaggc tggccccatg tgctcaaggg     2820

gatctaatgt ttgggctcca aactaaccat ctcggagctg ggctcctcat ttactgccaa     2880

accctcagct tatgtagcta gaaagggccc tggagtgaga aagcctggat tttcaaattg     2940

atgctcccct actgactagc tgtgccactc tgggcaaatg ctcttccttg agcctgtttc     3000

cacacctgta aagtggggat gatgatccta tctcactgct tttgtgagga ttacaggaaa     3060

gcacctgtcc tggctctgta cctggcacgt agtaggtgct cagttcatgc tggtttcctt     3120

cctgccttta gtagggacct gctctgtgct cacacctcgg ctgcatgcac cctgctgtga     3180

cggaggctag tgtggaagag gtcctgtcct cagggaatta actgtcttat tgggagacaa     3240

caactgtcct ccttggaaca cccaagaaac catgcaaagc agtggacaac acagaacacg     3300

ccctcctcct cgctgcctgc agctccaatc tgattctgct tgggaatggg cggagcacgt     3360

gggctgctta actgctgtat aggacaagcc ccttacccct ctctgggccc atgaattcct     3420

ggcttggttt atgttctgat ttgacacact gattttaatc ttcgaatcat gacactgagt     3480

gcagaggagg tggcattccg acagcaggac atacatgttg gtgtgaagac tgggacgaca     3540

ctgggtagaa tctagttttt aattattatt aatataaagg atcaaattaa tttaaatatg     3600

attctgaagt ctacagaact tttagttctg tgctgtctat gtggacactt tggtaaaatg     3660

caaattatga tatggacgtt atcattggtc tggtgagatg tttcatattt gtgacagtta     3720

atttaaaaat tatgagttaa tgctgcctgt gtctatgggg ttctgtcttc tttgatagcc     3780

atctattcat ctggatcatg ggaccctctc taatccttcc accaatcaaa taagctattg     3840

ctattggttt ggagttgaga tatcagtctc ggaaacttct gaaaaatgct aataattacc     3900

caaggattat gtcaaatttt aaaataaatg tgtgtgtgtt tctttaa                   3947


<210>  1542
<211>  8235
<212>  DNA
<213>  homo sapiens

<400>  1542
ttttagtggt ggagtcaatt tatttctgaa acgatctcat ttacctgaat gaggagctca       60

tatttatttt caggatttat gaggaatcca agatgaattt ggagcaggag aggccgtttg      120

tctgcagtgc cccaggctgc tcccagcgct tcccaacaga ggaccatctg atgattcata      180

ggcacaaaca tgaaatgact ttgaagtttc cttcaataaa aacagacaat atgttatcag      240

atcaaactcc gaccccaacg agattcctga agaactgcga ggaggtgggc ctcttcagcg      300

agctggactg ctccctggag cacgagttca ggaaggctca ggaagaggag agcagcaagc      360

ggaatatctc gatgcataat gcagttggtg gggccatgac ggggcccgga actcaccagc      420

ttagcagcgc tcggctgccc aaccatgaca ccaacgttgt gattcagcaa gccatgccgt      480

cgcctcagtc cagctctgtc atcactcagg caccttccac caaccgccag atcgggcctg      540

tcccaggctc tctatcttct ctgctacatc tccacaacag acagagacag cccatgccag      600

cctccatgcc tgggaccctg cccaacccta caatgccagg atcttccgcc gtcttgatgc      660

caatggagcg acaaatgtca gtgaactcca gcatcatggg gatgcaaggt ccaaatctca      720

gcaacccctg tgcttctccc caggtccagc caatgcattc agaagccaaa atgaggttga      780

aggctgcatt gactcaccac cctgctgcca tgtcaaatgg gaacatgaac accatgggac      840

acatgatgga gatgatgggc tcccggcagg accagacgcc acaccatcac atgcactcgc      900

acccgcatca gcaccagaca ctgccacccc atcaccctta cccacaccag caccagcacc      960

cagcacacca tcctcaccct caaccccatc accagcagaa ccatccacat caccactccc     1020

attcccacct tcatgcacac ccagcacatc accagacctc gccacatccg cccctgcaca     1080

ccggcaacca agcacaggtt tcaccagcaa cacaacagat gcagccaacc cagacaatac     1140

agccacccca gcccacaggg gggcgccggc gaagggtggt agacgaggat ccggacgaga     1200

ggcggcggaa atttctggaa cggaaccggg cagctgccac ccgctgcaga cagaagagga     1260

aggtctgggt gatgtcattg gaaaagaaag cagaagaact cacccagaca aacatgcagc     1320

ttcagaatga agtgtctatg ttgaaaaatg aggtggccca gctgaaacag ttgttgttaa     1380

cacataaaga ctgcccaata acagccatgc agaaagaatc acaaggatat ctaagtccag     1440

agagtagccc tcctgctagt cctgtcccag cttgctccca gcaacaagtc atccagcata     1500

ataccatcac tacttcctca tcggtcagcg aggtggtagg aagctccacc ctcagccagc     1560

tcaccactca cagaacagac ctgaatccga ttctttaaaa tgcaccatca gacctggcct     1620

ccaagaagag ctgtagcgta ccatgcgtcc tttcttttaa gggcattttt agaattaact     1680

cagacctgga agactcctca gttcttcaaa gactggcttt catttttata gttattatgg     1740

aaatgttgtc ttttatactt agttatataa gaaaaaaggg agttatgcaa ttaatatcta     1800

tcagcttggg aaacgctttg gtgcttttct ccagttttct ggtaccagtt acttgtttat     1860

aaactgaacc ttttctgtat atagccatgg tttcattctt atcagtccaa ccctttgcct     1920

gaaacattga atcttgttaa accacagctt ttagctaaaa tgaggtatac ctagatgtca     1980

agtaagacag atccaaggta actgggtagg aaatcttttg acatcttaac tcatgttgag     2040

tttgtgctgt ggtgtcacca gaattccaga taaacacaca gcctttccca tacctttttt     2100

tttcttacta taaaatatta taagatccat tgatgtccaa ataataccac caagcatctc     2160

ttcacctctc ctcctcttgg tccacttgct aatgcccagt tttcttctcc atttccactt     2220

tttcttaggc tccctattta ctattcattt tgacttcctt ctgttttatt tttttccctt     2280

tagcattgca tgtgaataag aaaataatgt ttaaagaaaa aaaaaaaaaa gcaaacctcc     2340

aaaacgtgga cctaaccatt gcttcactta cacttcaccc acagctggag ttcattcaac     2400

tcttgctttt cacaaaatag taaccaggag atgtttaatg tgcctgattt aatgttttta     2460

ataatcacag caaatgaaag gtggtttagt tataagtgaa gcatggttga ataccagctg     2520

gggagacact agggaaggga gctttgtaag ccttgattgc gaaagtccaa attttgatgt     2580

ggggctataa catgacaccc ttggattgcg actggtttta tacggcctgc ctataacgtt     2640

gaaaatccat gtactacata ataattcaga agggctctat tcactacaca gattacattg     2700

ttcaatcatc agctgctaat agcctaagat ttattttttt ttttttctta agcctatgga     2760

accggctttg ctgttctggg gggtgaaaat agactaacta ctggagaaac aaagagagaa     2820

agaaaaccca gtgtttccat aggggcactt ttagccttcc cacaacagtt aagcactctt     2880

tgactgctga aggaacccca tggatgaggt gcaggctact tcactctttt tttttctttt     2940

ttgagacaga gtctcaccta ttgcccagac tgaagtgcag tggtgcgatc atggatcact     3000

gcagcagcat cctccgagtt caagctatcc ttccacctcc gcctcctgag tagctgggac     3060

cacaggttca cataaccatg cctggctaat ttatttttac ttttatttta aaataaaaga     3120

tgaggtctgt cttatgttgc ccaggctggt ctcaaactat cctacttctt cctcccaaag     3180

tgttgggatt ataggtgtga gccactgcac ccagcctact tcactcttct gaattattct     3240

gatttatttt caacaacttt tgtgaacttg cccgtgatac aaagcagata gtccctgaac     3300

cacagtcgtg cctccttgaa acaagccatt ctactgtgct aatgttttaa tatcacatct     3360

cacaaataac aggggtgaat gtttctctct agcaatctag gcaggtgctg gtgtttcatc     3420

tccatttgaa tgcttgacct cttaatgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgttc     3480

atgggtttta aaagaacagt attttacaaa aggtgtagct tttataagag tgcagaaaag     3540

ggaaggatgt gtttttttct ctcactatag tataagaatc tattttggag aaaaaaagaa     3600

aatatgaggg tctcgaagca tgatttttat ataactagtt tcagttttat ctaataactt     3660

actttttaaa tcaatattta tcaacaatct ttccttgtat gcagtgcttt caaaagatgg     3720

ttttgagtgt ccagtgaaac ttatgacttg gatatatggt tgaagaatca aaacaaaagc     3780

aaaaaaaaaa agcaaaaaaa gaaaagagaa aaaaagaaaa aatgcaaatg gaataatttt     3840

ctattatatt ttagacaaac atatcatttt cgagtatttt aaatactgaa ttcatagttg     3900

ttgtttttta aattccaaca gtaacagctg aatggtttaa tctgactggc ttcctaagaa     3960

atgtttaaga ctcagcttta aaaagaagtt aacattcata tctctgtttt gaaatcaaaa     4020

atcatatttc aaaattcttt cctaggacca tctatgtgtc tcccctcccc tccacaaaaa     4080

ggagaaagag tgcattaaaa tgtttagttg ggttttttaa tttttaattt ttatgttatg     4140

ttttgctttg ttttaagtaa acaaaaattt ttctttcttt actgcatgca tagcacttaa     4200

taaaatggat ttttaaaaaa tccactagta atatcagaat gtccagggag tgactgtcac     4260

tacaatgatg gtttagttta cttctgttcc accttttgat tgaaatattt agttgttagg     4320

ctgaaagcct cggcagttaa gaacttgcct gagttttctt cgttcagcaa cttgacagtt     4380

tgactgatgt gcattatata tagctcaatt atgtctgttt tttatgctaa gtaggaaaac     4440

caaccacaca cattagcaaa ccggcctcaa catataatta gaataaactg tcttcttgtt     4500

ctactcaggg cctttaggtg tgttcattca cggtatggaa atacagtaaa tgaaagattc     4560

caactagttg tcagtgcttc ttgaaattcc aaacagaaag atacattggt caaatccaac     4620

acttggctta tcaatattaa gtcttttacc taaaggccca gccgtcacca gacaacagaa     4680

taatcaatct gcctgaaaat ccctcctcct tgtcctacac tttttgcctg tttgggagaa     4740

tatctttgta ctccattctc ctccctcagc cagttactgg gtcacccatc catgtgttca     4800

tgaatcaatc atcacggcct gcagagcacc tgtcctaagg agggaaaatc ctgtcacact     4860

gcctctcccc attcgtgtgt ggttttcttg atcggtgaga tctgtctctg aagtcactgc     4920

cagcctccct gggaacgtct atagtgcctc ccctgcctta tgtgatggga gttaacaact     4980

cagataagta cacctgagag catttctatc aggtaaactg tcacttaaat ggaggtgtcc     5040

acatcttaat tgtttctcct tgacacattt ctcaatccac gaagccagga gaggtagagt     5100

gaaaatccca gccatggatg aatgtactaa tttgaaagcc aagtgttaag tcggatgttt     5160

tcccgttaca ctactactca gccctctcct gcggccacat caacggatgc aagtcacagt     5220

cttaacacag cctgtgggag acaagcagtt tgtgtgctca cagtatatat tatagtaatt     5280

agggtgactt agagcaaata ctcttcagat cctatgtagt cagtgaaaca aaatggagag     5340

cgtattctga tagaaggacg tcgacggtga atgttctggt ggttgttgcc tgttaagtaa     5400

actttagtgt gtaagttgag tttgtcatta aaatcataaa ccagctgcgg taacagacaa     5460

gcctttggct ggggagtttt aagcctcggt aactgctata aaactagcca tccagttagg     5520

atagaatgtg tttctttctg gttaaaaaaa ggaaaaacca tctaagaaaa tatatatgta     5580

tgtatgtgtg tatacagtgg aattcaaagg accaaagcaa aatttgaaca ggaatctatt     5640

aatttagaat tttataagat atttattaat aaatgttatt tttaaacatt ccatttgaac     5700

agtattctgt aggatctact tgtttttaaa gtgttagtcc ataataaact actatagtta     5760

tgtgtatttt catttttcag ggtttcaaat ggctattctc catcatttgg tggaaatgtt     5820

tgcttagatc tctgtgcata gacatttcaa ggatttttat tgctctgtga gttatttttt     5880

aatcaacatt ctgaacagtt ttttttaaac atttatttct gtgtgttcat ttttaaagta     5940

agctctttca tttaggaagc agagttcagc taaagggaat cagtaactct aactggaaca     6000

gctttcttgt agaagtgtaa aaacagcttc atctctgcct ctctccaccc caccccaatt     6060

tcctagaaag ccttgcacta ttcagctccc ttagtgcttt ttgtcccttc ccgaacaata     6120

tgcagtagct ttaagccatt caagctccat tatgcagtat atctgagaag ggaaaggaaa     6180

caacccattt aaatttgaat aaaaccgtgc ctatgcgaac agtagcaatt tagaatctct     6240

tttctgcttt taaaataatt tatatttaaa aattgcactt tagctttttg atccctttgt     6300

atttctctta ttctctttct aacctcttct ctgtcctcaa acttgccttt gctctccttt     6360

acaatacccc ccacccctcc tccaaggctc tgagcggcat catttaaaat actttacaga     6420

tatttgcacc aggtacattt atgtgcgtcc attggtagca cagctgagac ctgtgtctca     6480

catcagccta ggtgaagcct actacaagaa tgccaaggag aagagccagt acactatatg     6540

gtttatactc tttatccctt tattcatagc atgtttttta aaaatgttat attatgcaac     6600

agatgtgagg cagcagctaa gctatactta agaattttct ctcaccttcc aaaccaaagt     6660

gtcctgaata agccaggaga cttattcttt tgtgcaccct ggtgcacatc tgactgttgt     6720

cctagccata gactctctga ggccactgaa agaacagtgg ccctatcgat ttcattccta     6780

ggtctcaaaa atacaatgtt gccttgtaac ataattaggg acagcacctc tatttcacaa     6840

ttataatcta aggtaggata agacgacaca gcagcaataa acttacaagt aaaattcaat     6900

accaaaacaa acacaaagaa atttaaaaaa caaaaaacct agctcatcat gttgtgaaaa     6960

tgaaaaagtg aatgtccatt caaaatattt tactatttct tgtggagttt ttcagtgatg     7020

taatgcttgt agccaaattg cttaaagagt gtttatatat ttttttcctt ataaattgtc     7080

tattttttaa aaaagctatt taaccacagc tgaagtgggg ggtaaggcca aattgccaac     7140

acttgttaaa agattaatac tcttaagtgg cactctgata cctttccaac ttgtcatcag     7200

aaaggaatca ataattacca actgttgtat ttagaccaac ttacaatatc tagctcatta     7260

gaagccagga tctagaaagc tccttctaag ccatttaaga tattcttaca ttgagcttca     7320

tattatagaa ctttatagga ttggatattt tacaatagaa taatttagcc tcaggactga     7380

gaatgtggaa gctgaataaa ttagctttaa atacatcatt aaaatcttat gcacaataag     7440

ctcattagat tctagttttc tcctttagaa taccaatgcc acagacacta caggagataa     7500

tgaaaggtat cagttgtgtt gagtggaggg agtttaagag aaaggaccct tcccaaccag     7560

cagccagtag aaaatacaac ctactcacct ttttcccttc taagttctgc taaatcacat     7620

ctgcctcata gagaaaggaa tgttgccttt gagaactgtc ttggagaaca gataagcttg     7680

aaatgttctc tctagagagg acatagggtt tgggatcctc tgaaaaggcc cagaaaaata     7740

gctcagttca aatacaatgt tctaggacaa ttggaatata aatattgtcc aaaaatataa     7800

ttaaaagaaa aaagtttagc actgtgtaaa gtaagtgtta actgaggaag tcccaaaaag     7860

gtgctgtcac tttaagttct ggacttgggg ttctttgtat ttgtaaacag caaagcattt     7920

gtgtttgttt gtctatttgt aaagcaacca ccttccttat tggaaggaga aaaaaagggg     7980

tacatacatg taaatacttg ctgcagcatt taatatgttt aattttgtgt taagcttttt     8040

gttgcatcgt gaacacattt attgttacca atggacaatg agttcattaa gactgttcaa     8100

ctaggtcaga tttttacatc tctttctagc aagaagagac aagattttgt gcatttgtac     8160

aaatgttaat atcactgcaa ttccaatata ataaagcact caaatgcaaa taaaaaaaaa     8220

aaaaaaaaaa aaaaa                                                      8235


<210>  1543
<211>  8733
<212>  DNA
<213>  homo sapiens

<400>  1543
gcgccggggt cgccagctcc tcgcccacct ccctccctgt gggagaagag gaggagggga       60

agtgactgcg gagttgatga actttgcaca tccagaaacg ccattttgat tccttttccg      120

gaacaagttt gcatctctcc tcggtctctc cctgaagccc accggtcccc aacgcatcat      180

gccagggagc caagcgtcct gcccggccgt tgctccgact gtgtgttcca ggagtggtgg      240

ctctgaggtg tgaccctgcc cacgtttggg cccagccagg ttcagccccc caataaggag      300

ggcagcttga taacacaaag aaaacagtgt caacgagtac taccaagaga agaagacaag      360

aggtcaacac agactcattt tctactccgt gtgaatgata gctacagcag gggaaagttt      420

catagtctat cagtgggtca gaaaatggag ttttatagca gaggcttctt agaagcttaa      480

acccctgtcc caatgacgtc aagttcgccc gctggcttgg aaggttcaga cctatcttcc      540

atcaacacca tgatgtcggc ggtcatgagt gtagggaagg tcacagagaa tggcgggagc      600

ccccagggga tcaagtcccc ctcgaagcct ccaggaccaa atcggattgg cagaaggaac      660

caggaaacga aagaggagaa gtcttcctat aactgccccc tgtgtgagaa gatttgcact      720

acccagcacc agctgaccat gcacattcgc cagcacaaca cagacactgg aggagccgac      780

cactcatgca gcatctgcgg aaagtcactg agctcggcca gctccctcga tcgccacatg      840

ctggtgcact ctggcgagag gccttacaag tgcactgtgt gtggccagtc atttaccacc      900

aatgggaaca tgcacagaca tatgaagatc catgagaagg accctaacag tgccacagcc      960

acagcccctc catctcctct gaaacgtagg cgattgtcct ccaagaggaa actgagtcac     1020

gatgccgagt cagagagaga agacccagca ccagctaaaa agatggtaga agacgggcag     1080

tcaggtgact tggagaagaa agctgatgaa gtctttcact gcccagtatg tttcaaggag     1140

tttgtttgca agtatggact ggagacccac atggagaccc attcagataa cccactaaga     1200

tgtgacattt gttgtgtcac ctttcgaaca catcgaggac tgctgcgtca caacgcgctt     1260

gtccacaaac aacttcccag ggatgcaatg ggcagacctt tcatacagaa caacccttca     1320

attcctgctg gcttccacga cttaggattc acggacttct cctgtaggaa gtttcctcgc     1380

atttctcagg cctggtgcga aacaaacctg cggaggtgca tcagcgagca acaccgtttt     1440

gtctgcgaca cctgtgacaa ggcgttcccc atgctctgct cactggctct gcacaagcag     1500

acccatgtgg cggcagacca gggtcaagaa aagccgcagg ccacgcccct gcctggtgac     1560

gccctggacc agaagggctt cctggccttg cttggcctgc agcacaccaa agacgtcagg     1620

cctgcccccg ccgaggagcc cctgccggat gacaaccagg caattcagct ccagacactc     1680

aagtgtcagc tacctcagga ccccggctgc accaacctgc tgagcctgtc acctttcgaa     1740

gctgcttccc taggcggttc tctcacagtt ctccccgcga ccaaggacag cataaagcac     1800

ctgtccctgc agcccttcca gaagggcttc atcatccagc ctgacagcag cattgtggtc     1860

aagcccatct ctggcgagtc ggccatcgag ctggcagaca tccagcaaat tctgaagatg     1920

gcagcctcgg ctccccctca gatcagtctt ccgcccttct ccaaggcccc tgccgcccca     1980

ctgcaggcga tcttcaagca catgccccct ctgaagccaa agcccctggt cacaccacgg     2040

acggtggtgg ccacctccac gcccccgcct ctcatcaacg cccagcaggc ttccccgggc     2100

tgtatcagcc ccagcctgcc gccaccgccc ctgaagctcc tcaaaggctc agtggaggcg     2160

gcctccaacg cccacctgct gcagtccaag tccgggaccc agccccacgc ggccacgcgg     2220

ctctccctgc agcagccgcg ggcggagctg ccgggccagc ctgagatgaa gacgcagctg     2280

gagcaggaca gcatcatcga ggccctgctg ccgctgagca tggaggccaa gatcaagcag     2340

gagatcacag agggggaact caaggccttc atgacagcgc ccggcggcaa gaagacgccc     2400

gccatgcgca aggtgctcta cccctgccgc ttctgcaacc aggtgtttgc cttctcgggg     2460

gtcttgcgtg cccacgtgcg ctcccacctg ggcatctcgc cataccagtg caacatctgc     2520

gactacatcg ccgccgacaa ggccgcgctc atccgccacc tgcgcacgca cagtggggag     2580

cggccctaca tttgcaagat ctgccactac cccttcactg tcaaagccaa ctgcgagcgg     2640

cacctgcgca agaagcacct caaggccacc cgcaaggata tcgagaagaa catcgagtat     2700

gtgagtagca gcgcggccga gctggtggac gccttctgcg ccccggacac cgtgtgccgg     2760

ctgtgcggcg aggacctcaa gcactatcgt gccctgcgca tccacatgcg cacgcactgc     2820

ggccgcggcc tgggcggggg ccacaagggc cgcaagccct tcgagtgcaa ggagtgcagc     2880

gccgcgttcg cggccaagcg caactgcatc caccacatcc tcaagcagca cctgcacgtg     2940

cccgagcagg acatcgagag ctacgtgctg gccgccgacg gcctgggccc cgcagaggcg     3000

ccggccgctg aggcgtcggg gcgcggggag gacagtggct gcgctgccct tggtgactgc     3060

aagcccctca ctgccttcct ggaaccccag aacggctttc ttcacagggg ccccacccag     3120

cctccacctc cccatgtctc gatcaagttg gagcccgcca gtagctttgc ggtggacttc     3180

aatgagcccc tggacttctc gcagaagggc ctggccctgg tccaagtgaa gcaggaaaac     3240

atctcctttc tgagcccttc ttccctggtc ccctatgact gctccatgga gcccatcgac     3300

ctgtccatcc ccaagaactt caggaaaggg gacaaggatt tggccactcc cagcgaagcc     3360

aagaagcctg aggaggaggc ggggagcagc gagcagccct ctccctgccc agcacccggc     3420

ccttctcttc ctgtaacttt ggggcccagc ggaatcctgg aaagccccat ggcccctgct     3480

ccggcggcca ccccggaacc cccagcacag cccctgcagg gccctgttca gctggcggtc     3540

ccaatctact cctcagccct ggtcagcagc cctccactcg tgggcagctc agccctcctg     3600

agtggcacag ccttgctgcg tccactgcgg cccaagcccc cgctgctttt gccaaagccc     3660

cccgtgacag aagagctgcc cccgctggcc tccattgccc agatcatctc atctgtatcc     3720

tcggccccca ccctgctgaa aaccaaggtg gcggacccag ggcccgcaag cactggcagt     3780

aacaccacgg cttcagacag cttaggaggt tctgtcccca aagccgccac caccgccacc     3840

cccgctgcca ccaccagccc aaaagagtct agtgagcctc ccgctccagc cagcagccca     3900

gaggctgcct ctcccaccga gcagggccca gcgggcacgt cgaagaagag gggccggaaa     3960

agggggatga ggagccgacc ccgcgccaac agcggcgggg tggacctgga ctccagcggg     4020

gagtttgcca gcatcgagaa gatgctggcc accacagaca ccaacaagtt cagtccgttt     4080

ctgcagacag cggaggacaa cactcaggat gaggtggccg gagcccctgc cgaccaccat     4140

gggcccagtg atgaagagca gggcagtccc ccagaagaca agctgctgag ggccaagcgg     4200

aactcgtaca ccaactgcct gcagaagatc acctgtcccc actgtccccg ggttttccct     4260

tgggccagct ccctacagag gcacatgctc acacacactg gtcagaaacc cttcccttgt     4320

caaaaatgcg atgccttctt ttctaccaaa tctaactgtg aacgccacca gttgcgcaaa     4380

cacggagtta ccacctgttc cctgagaaga aacgggctta tcccccagtc aaaagagagt     4440

gatgttggat cccatgatag cacagacagt cagtcggatg cggagactgc agccgccgcg     4500

ggcgaagtgc tagacctcac ctcacgggac agagagcagc cgtcggaggg cgccactgag     4560

ctccgccagg tcgcagggga tgcgcctgtg gagcaggcca cggcggaaac ggcctcgccg     4620

gtgcaccggg aagagcacgg gcgtggggag agccatgagc cggaggagga gcatggcact     4680

gaggagagca ctggggacgc cgacggcgcg gaagaggacg cgtcgagcaa ccagagcctg     4740

gacctggact tcgccaccaa gctcatggac ttcaagctgg cggagggcga cggcgaggca     4800

ggcgccgggg gcgcggcctc gcaggagcag aagctcgcct gcgacacctg tgggaagagc     4860

ttcaagttcc tgggcaccct gagccgccac cggaaggcgc acggccgcca ggagcccaag     4920

gacgagaagg gagatggcgc cagcactgca gaggaggggc cccagcccgc ccctgaacag     4980

gaggagaagc cccccgagac cccggcagag gtggtggagt cggccccggg tgccggggag     5040

gccccggcgg aaaagctcgc ggaggagacg gagggcccct ccgacgggga gagcgcggcc     5100

gagaaaaggt cctcagagaa gagcgacgat gacaagaaac caaagacaga ctcccccaaa     5160

agcgtggcca gcaaggcaga caagaggaag aaggtctgca gcgtgtgcaa caagcggttc     5220

tggtcgctgc aggacctgac ccggcacatg cgctcccaca caggggaaag gccatacaaa     5280

tgtcagacct gcgagcgaac cttcaccttg aagcacagcc tggttcgcca ccagcggatc     5340

caccagaaag ccaggcatgc caaacaccac gggaaggaca gcgacaagga agagcggggt     5400

gaggaggaca gcgagaatga gtccacccac agcggcaaca acgccgtctc agagaacgag     5460

gctgagctgg ctcccaatgc cagcaaccac atggctgtca cccggagccg gaaggagggc     5520

ttggccagtg ccaccaagga ctgcagccac agggaggaga aggtcacggc agggtggccg     5580

tctgagcctg gccagggtga ccttaaccca gagagcccgg cggccctggg gcaggacctg     5640

ctggagccgc gcagcaagag gcctgcccac ccaatcctgg ccacagctga tggcgcctcc     5700

cagctcgtgg ggatggagtg acagcctcag tccccctcag cacagacaaa agccagcaga     5760

gcaaagcgtc tatacttcat ggggtttcct cagtgccctt tggctgttga ggagtgagag     5820

agagagagag agagagagag agagagagag agagagacaa gcaggagcgt ggctgctcgc     5880

tcagtgccat agccttaccg cagcctgcgc gggaggccac agcccgtgcc gattccagtg     5940

ccttaactac ttaccggatc cctccatatt atcatgggtg ttgtattttt ccaaaatgac     6000

ttcttaaaca aaacaaatat tataatgaat tgtctggaga ggacctcttc atttgagcat     6060

tagcgttatt ttgtattggt gtgtgtgagc ttgttcttgt gaatctgtga tagcaccgtt     6120

tgttctgtga gctggaaaca gaaggaaaaa acataccctt gggtacccat agccaataac     6180

tggaagaaaa tgatgtgaat ttcatgtaaa tgaccagagg aaagatggat aagatgataa     6240

tttcttaaat agacattttc cttttttctt tgtgcttcat ggtggagctg tcatctggtc     6300

cttggtatta caggatgtgg ttgatgaagg tttccaatat ggtttcaggc caaaaccagg     6360

gaagattcta gcttcagcct catgtccatt tccagtctgt cagcattaga catggtcact     6420

gttcaagttt caagacatcc attcttaact atagagaaga gttactcccc tggcgtctta     6480

acctatggaa aacatgcacg gataggatat atttgattgc ctcctcttcc ctttcagtat     6540

atgtattatt aatattatta ttattattat tattattagt tcatcagttt gctgttctct     6600

gcagtgagca gaatcaaatg ggcaatattt gtcctgggag acctgtgccg cacccaggtc     6660

cccgtgttaa cgtgtgcctg cggttgtggt tggcaccctc gggtggtagc tcttctactg     6720

taatgagaca agcctttctt ctgtcactgc agaatttaga aggggccgtg agcagtcttc     6780

ccaagcatgg tccaggagca gctcagagag ggtggagtga ggatgcatgc atccagggaa     6840

caggcatcaa gaagccaggg ccgtgcctgg agcactgcag agatgacttt ggagaaagca     6900

aagcagtgac ccagtgacca ggcacattac tcgtgagcga ggtattccca gtcttcctgc     6960

taagcctaat ccaagcctta cccagctgtg ctactgtcat ttgcaaagca aggaaatact     7020

actactggta ataaaactac acatgcaaga tgtcagataa gaaataggtt tatatttacc     7080

ttcctgcgat gtggggttgg tgcttgaaga taaatgtgct gtttctagtt tcttaaatag     7140

cccacacccc tggatgcaaa aaggcagggt tatttttacc catgagcatc ctgtgcaggc     7200

aatagacttc cctcactgtc tccgcctgca gggaggagaa tgtaccccac tgcacctgag     7260

ctcctggtcc ctcagccaag acctcagggg tccccagcca gcctgctgct ggggacccct     7320

gtgcttgctg cagtgtatgg agcctcttgc cttcccctgg ggaggcaccc ctgtacccca     7380

gcttccttcc cctggccttt tctggcccca gtgctcctcc tttacataga cttgttcaca     7440

cagaaacgtg cacgccccct tttctccgcc acttcaccag tttctgaaat ccaacctccc     7500

agacttcaca ggaagataga tattcttgag ataatgaaaa gtgatatctt cgcatacgaa     7560

aggaaaaaag gttgaggtat atatgatttt taactgtatt aggggtgtat gaaccagttt     7620

aaaaacgagg ttttatttac tgtagagatg aatgcaaatc agaaccaatg atcccttggc     7680

ctacttagtt aaaaccagtt catacatccc ttagggtttt tattattatt attattatta     7740

ttacagttgt tattgttgtt tttgttgtta ttattatttg gggtttcttg tgttttttct     7800

ttgcgactct ccacactaaa cttgcaatat tgtggggaga agctgtgact aaactctacg     7860

ctgcggtgag atgtagcagt aatcagctcc cagcgacgtg tgtagctggg gctgccgctc     7920

gcaataatca ctattgattt aaagctttac ttagccttga tctgtaccct cgtagtcaat     7980

aaggtcttgc cacattttat tagtgaggtg gagaaacgta ttatttgttt gttgtttttg     8040

cccttccccc accccccaat attaaactgt gaaatttgtg atttgtttaa actctgggtg     8100

aatcatagct tagtttgcat gtccagctaa tttgtttcta tacattttgt ttgattctct     8160

ttctccttct ctcagggctt ttacaaaaaa atatatatat atggatcttc tgaaaagttt     8220

tttgaggtgc aagttttttc tctttttttt tttttttttt ttttctcatt gattaatgga     8280

catgatgctg agattcaatc actacatgaa acacctggct gtgaaaacaa aacaacccag     8340

agggctgtgt tccaagcagc gctggggaag ctacgtaaca gtcggatgcc agttttggaa     8400

gattcaccat gcgttctgac cctctgttcg tctctttcct ctcctctttc ttcaagaagg     8460

aaattgatcc tagtgatttc agcccatgca ttaaacagga aacaataata aatttgtaga     8520

attcatattt ttctaaaggg aacttaaaaa ctgctgctac atgttatgta caaaactggt     8580

ttatgccaca tgaacagaga atcacaagtt tggttttggt actttttgtt cctctttgta     8640

ttcagttgta tagaacttcc aaattcagaa tgagaagaaa gctgttctgt atcaaaccat     8700

ttaagcaata aatgttatat tttaaaagct gca                                  8733


<210>  1544
<211>  4260
<212>  DNA
<213>  homo sapiens

<400>  1544
gtgcagttga gtcgcgagta cggctgagct gcgtaccggc ctccctggct ctcacactcc       60

ctctctgctc ccgctctcct aatctcctct ggcatgcggt cagccccctg cccagggacc      120

acaggagagt tcttgtaagg actgttagtc cctgcttacc tgaaagccaa gcgctctagc      180

agagctttaa agttggagcc gccaccctcc ctaccgcccc atgccccttc accccactcc      240

gaaattcacc gacctttgca tgcactgcct aaggatttca gagtgaggca aagcagtcgg      300

caaatctacc ctggcttttc gtataaaaat cctctcgtct aggtaccctg gctcactgaa      360

gactctgcag atataccctt ataagaggga gggtggggga gggaaaagaa cgagagaggg      420

aggaaagaat gaaaaggaga ggatgccagg aggtccgtgc ttctgccaag agtcccaatt      480

agatgcgacg gcttcagcct ggtcaaggtg aaggaaagtt gcttccgcgc ctaggaagtg      540

ggtttgcctg ataagagaag gaggagggga ctcggctggg aagagctccc ctcccctccg      600

cggaagacca ctgggtcccc tctttcccca acctcctccc tctcttctac tccacccctc      660

cgttttccca ctccccactg actcggatgc ctggatgttc tgccaccggg cagtggtcca      720

gcgtgcagcc gggagggggc aggggcaggg ggcactgtga caggaagctg cgcgcacaag      780

ttggccattt cgagggcaaa ataagttctc ccttggattt ggaaaggaca aagccagtaa      840

gctacctctt ttgtgtcgga tgaggaggac caaccatgag ccagagcccg ggtgcaggct      900

caccgccgcc gctgccaccg cggtcagctc cagttcctgc caggagttgt cggtgcgagg      960

aattttgtga caggctctgt tagtctgttc ctcccttatt tgaaggacag gccaaagatc     1020

cagtttggaa atgagagagg actagcatga cacattggct ccaccattga tatctcccag     1080

aggtacagaa acaggattca tgaagatgtt gacaagactg caagttctta ccttagcttt     1140

gttttcaaag ggatttttac tctctttagg ggaccataac tttctaagga gagagattaa     1200

aatagaaggt gaccttgttt tagggggcct gtttcctatt aacgaaaaag gcactggaac     1260

tgaagaatgt gggcgaatca atgaagaccg agggattcaa cgcctggaag ccatgttgtt     1320

tgctattgat gaaatcaaca aagatgatta cttgctacca ggagtgaagt tgggtgttca     1380

cattttggat acatgttcaa gggataccta tgcattggag caatcactgg agtttgtcag     1440

ggcatctttg acaaaagtgg atgaagctga gtatatgtgt cctgatggat cctatgccat     1500

tcaagaaaac atcccacttc tcattgcagg ggtcattggt ggctcttata gcagtgtttc     1560

catacaggtg gcaaacctgc tgcggctctt ccagatccct cagatcagct acgcatccac     1620

cagcgccaaa ctcagtgata agtcgcgcta tgattacttt gccaggaccg tgccccccga     1680

cttctaccag gccaaagcca tggctgagat cttgcgcttc ttcaactgga cctacgtgtc     1740

cacagtagcc tccgagggtg attacgggga gacagggatc gaggccttcg agcaggaagc     1800

ccgcctgcgc aacatctgca tcgctacggc ggagaaggtg ggccgctcca acatccgcaa     1860

gtcctacgac agcgtgatcc gagaactgtt gcagaagccc aacgcgcgcg tcgtggtcct     1920

cttcatgcgc agcgacgact cgcgggagct cattgcagcc gccagccgcg ccaatgcctc     1980

cttcacctgg gtggccagcg acggctgggg cgcgcaggag agcatcatca agggcagcga     2040

gcatgtggcc tacggcgcca tcaccctgga gctggcctcc cagcctgtcc gccagttcga     2100

ccgctacttc cagagcctca acccctacaa caaccaccgc aacccctggt tccgggactt     2160

ctgggagcaa aagtttcagt gcagcctcca gaacaaacgc aaccacaggc gcgtctgcga     2220

caagcacctg gccatcgaca gcagcaacta cgagcaagag tccaagatca tgtttgtggt     2280

gaacgcggtg tatgccatgg cccacgcttt gcacaaaatg cagcgcaccc tctgtcccaa     2340

cactaccaag ctttgtgatg ctatgaagat cctggatggg aagaagttgt acaaggatta     2400

cttgctgaaa atcaacttca cggctccatt caacccaaat aaagatgcag atagcatagt     2460

caagtttgac acttttggag atggaatggg gcgatacaac gtgttcaatt tccaaaatgt     2520

aggtggaaag tattcctact tgaaagttgg tcactgggca gaaaccttat cgctagatgt     2580

caactctatc cactggtccc ggaactcagt ccccacttcc cagtgcagcg acccctgtgc     2640

ccccaatgaa atgaagaata tgcaaccagg ggatgtctgc tgctggattt gcatcccctg     2700

tgaaccctac gaatacctgg ctgatgagtt tacctgtatg gattgtgggt ctggacagtg     2760

gcccactgca gacctaactg gatgctatga ccttcctgag gactacatca ggtgggaaga     2820

cgcctgggcc attggcccag tcaccattgc ctgtctgggt tttatgtgta catgcatggt     2880

tgtaactgtt tttatcaagc acaacaacac acccttggtc aaagcatcgg gccgagaact     2940

ctgctacatc ttattgtttg gggttggcct gtcatactgc atgacattct tcttcattgc     3000

caagccatca ccagtcatct gtgcattgcg ccgactcggg ctggggagtt ccttcgctat     3060

ctgttactca gccctgctga ccaagacaaa ctgcattgcc cgcatcttcg atggggtcaa     3120

gaatggcgct cagaggccaa aattcatcag ccccagttct caggttttca tctgcctggg     3180

tctgatcctg gtgcaaattg tgatggtgtc tgtgtggctc atcctggagg ccccaggcac     3240

caggaggtat acccttgcag agaagcggga aacagtcatc ctaaaatgca atgtcaaaga     3300

ttccagcatg ttgatctctc ttacctacga tgtgatcctg gtgatcttat gcactgtgta     3360

cgccttcaaa acgcggaagt gcccagaaaa tttcaacgaa gctaagttca taggttttac     3420

catgtacacc acgtgcatca tctggttggc cttcctccct atattttatg tgacatcaag     3480

tgactacaga gtgcagacga caaccatgtg catctctgtc agcctgagtg gctttgtggt     3540

cttgggctgt ttgtttgcac ccaaggttca catcatcctg tttcaacccc agaagaatgt     3600

tgtcacacac agactgcacc tcaacaggtt cagtgtcagt ggaactggga ccacatactc     3660

tcagtcctct gcaagcacgt atgtgccaac ggtgtgcaat gggcgggaag tcctcgactc     3720

caccacctca tctctgtgat tgtgaattgc agttcagttc ttgtgttttt agactgttag     3780

acaaaagtgc tcacgtgcag ctccagaata tggaaacaga gcaaaagaac aaccctagta     3840

ccttttttta gaaacagtac gataaattat ttttgaggac tgtatatagt gatgtgctag     3900

aactttctag gctgagtcta gtgcccctat tattaacaat tcccccagaa catggaaata     3960

accattgttt acagagctga gcattggtga cagggtctga catggtcagt ctactaaaaa     4020

acaaaaaaaa aaaacaaaaa aaaaaaaaca aaagaaaaaa ataaaaatac ggtggcaata     4080

ttatgtaacc ttttttccta tgaagttttt tgtaggtcct tgttgtaact aatttaggat     4140

gagtttctat gttgtatatt aaagttacat tatgtgtaac agattgattt tctcagcaca     4200

aaataaaaag catctgtatt aatgtaaaga tactgagaat aaaaccttca aggttttcca     4260


<210>  1545
<211>  4230
<212>  DNA
<213>  homo sapiens

<400>  1545
gaagggtcgg gggatccctc cgccgccagc gcgtggtccc ggccccctcc acccgccgtc       60

tcggccgcgg ccagcagccc ctgccccccg ggggacgctg acggccgccc ggcgcgccgc      120

cctagcagac ggacaggggg cgctgcgcgc ggcctggggc aacccgggcc acaggggcag      180

gaaagtgagg gcccaggtcg gcccgggcgt gcaggggccc cgggttcgca gcggcggccg      240

cggcagcgat agcggcacta gcagcagcgg gagtgccggg ttgagccggg aagccgatgg      300

cggcggctgc ggcggctccg attcctcgct gactgcccgt ccgccctcct gcatcgagcg      360

ccatgttacc gacccaagct ggggccgcgg cggctctggg ccggggctcg gccctggggg      420

gcagcctgaa ccggaccccg acggggcggc cgggcggcgg cggcgggaca cgcggggcta      480

acgggggccg ggtccccggg aatggcgcgg ggctcgggcc cggccgcctg gagcgggagg      540

ctgcggcagc ggcggcaacc accccggcgc ccaccgcggg ggccctctac agcggcagcg      600

agggcgactc ggagtcgggc gaggaggagg agctgggcgc cgagcggcgc ggcctgaagc      660

ggagcctgag cgagatggag atcggtatgg tggtcggtgg gcccgaggcg tcggcagcgg      720

ccaccggggg ctacgggccg gtgagcggcg cggtgagcgg ggccaagccg ggtaagaaga      780

cccggggccg cgtgaagatc aagatggagt tcatcgacaa caagctgcgg cgctacacga      840

ccttcagcaa gaggaagacg ggcatcatga agaaggccta tgagctgtcc acgctgacag      900

ggacacaggt gctgttgctg gtggccagtg agacaggcca tgtgtatacc tttgccaccc      960

gaaaactgca gcccatgatc accagtgaga ccggcaaggc actgattcag acctgcctca     1020

actcgccaga ctctccaccc cgttcagacc ccacaacaga ccagagaatg agtgccactg     1080

gctttgaaga gacagatctc acctaccagg tgtcggagtc tgacagcagt ggggagacca     1140

aggacacact gaagccggcg ttcacagtca ccaacctgcc gggtacaacc tccaccatcc     1200

aaacagcacc tagcacctct accaccatgc aagtcagcag cggcccctcc tttcccatca     1260

ccaactacct ggcaccagtg tctgctagtg tcagccccag tgctgtcagc agtgccaatg     1320

ggactgtgct gaagagtaca ggcagcggcc ctgtctcctc tgggggcctt atgcagctgc     1380

ctaccagctt caccctcatg cctggtgggg cagtggccca gcaggtccca gtgcaggcca     1440

ttcaagtgca ccaggcccca cagcaagcgt ctccctcccg tgacagcagc acagacctca     1500

cgcagacctc ctccagcggg acagtgacgc tgcccgccac catcatgacg tcatccgtgc     1560

ccacaactgt gggtggccac atgatgtacc ctagcccgca tgcggtgatg tatgccccca     1620

cctcgggcct gggtgatggc agcctcaccg tgctgaatgc cttctcccag gcaccatcca     1680

ccatgcaggt gtcacacagc caggtccagg agccaggtgg cgtcccccag gtgttcctga     1740

cagcatcatc tgggacagtg cagatccctg tttcagcagt tcagctccac cagatggctg     1800

tgatagggca gcaggccggg agcagcagca acctcaccga gctacaggtg gtgaacctgg     1860

acaccgccca cagcaccaag agtgaatgat ccgcccgccg ccctggacag atggcccaag     1920

ggatggcacc acttatttat tgttgccttt tcacgttttc tttacacaca cgttgacggg     1980

ccgcaggagg gaggcgggga ggaggaacgg gcagccacag gactgagccc tctcactcca     2040

gccaaagaaa tgggcctgcc tgcctccacc cgtcctccct cagcctcccc ttcttcccgc     2100

cccacctccc atttctgttg ctggaggggc tgtcctcctt cctgggaccc cctcgccagc     2160

ttggctcgat gtttgccatg agtattagct tacccaatgg gaccgtgccc cacctcccca     2220

cacacaggcc ttctgtgggg ctgggcaccg tgtcctcctc tgaggaagca gttggggccc     2280

tcttgccagc ctccttgctg accccaggtc agccctgtgt ctgtcacagg ctgggtcaaa     2340

agagccctgg ctctgcccct cagggggcca gctggggaga tgggggcttc ttcctcacac     2400

tgctgtcctc tcccccttca gctcctgagt agctgggcct gtgcactggg caggttcctg     2460

gggccgcctg ccctgccttg ccgctcccct tggacctcca ggggctcctg ggttggaggg     2520

aaccaccagc gttcccttct cccccttgtc ttcccccctc tcctcccagc tgctttactt     2580

aaagttgatt ttgaactttt tatttgagga gacgaagtga aaacaaatct ataaatatat     2640

atttttaaaa tatttaactt ttttttatgg cgtttttctc gtccccctcc ctgcccaaac     2700

tccccttccc tggggagccc tcaggctccc cagaactggc tgggcccctg gggacagagc     2760

caccccatga gctcggggtc caccagtgtg tgggggagat tctgggtttg cccagtcctg     2820

ggttgtttcc aggagaaagc cgggggaggg gccctcaggc cattccccaa cggggtgggg     2880

agggtgaccc acagctctgg gcctcttttt gccctttagg gctgttgcta gggagaggga     2940

agagggagac caaatgtcgg ggttggggtg ggagggcgtc aggcagaggc aactgacttc     3000

atttgtgcca cacgcatggg cattgcagcc ttgcgctgtc ccaggcatgc agctgcctgg     3060

ggcccaagtt gcagtgagca gggtggggtc tgggaggggg tgagaggcag gaatgggggt     3120

cagaagaagt gggagcagct tcttgggctg agtgcagcca aaggggagcc agaaatgggc     3180

agttctccca gggagtgagc agctactgta acttttttaa attaagacaa aaagccttga     3240

agaaaatgac tttatttttc taagtgtaac ctcagtattt atgtaatttg tacaggggcc     3300

atgccccacc cccctcctcc ccctttgggg tagaccttga gggtgggcca gcataggggg     3360

gagggtcttt taccctgtgt cagagcctac cttcaccacc tatatccaga aggggagctt     3420

tttcagaaac agggcagcag tggggtgaaa ttttcttaac ccctaagact gccttcagta     3480

ggaacaagct ggcttctgtg attaggtgaa gggatggggg aagattttat gcacagccta     3540

gttatcaagg ggatgatttg ccgacatgtt tgagaacccc ctaacctcta accctcattg     3600

ctgtcttgcc ccagtttggg gtgccaagat ggaagtcacc tttctgggct ttctcctgga     3660

gatagctggg gcttatgggt ggctttcaag gctggggcat ggcaaatcag gggccagaga     3720

gcaggggagc ttgggactca ggtctgtaac tgcccagccc cttttctctg ctcttgtttc     3780

actccaccat cactcactca ctccccactc ccccacccat ggggaggaga cctttgatga     3840

attcttcctc tccttcccac aaaagacaga cccagtgagt gaatcaggca aagtgcttat     3900

aatgtgtgtt gtgtgagcgt ggccttggga ggacatgcgt gtgtcaggga tgagttgagg     3960

tgatattttt atgtgcagcg acccttggtg tttcccttcc tcggtggctc tggggtatgt     4020

gtgtgtgggt gtgtgcgcct gagtgagtgt gtgtgcttga atgtgagtgt gtatgtcagt     4080

ggtttctact tcccctggga tgctgaccca ggaatagtgg acatggtcac agtcctatgt     4140

acagagcttt cttttgtatt aaaaaaaaat actctttcaa taaatgtatc atttttgtgc     4200

acagaaaaaa aaaaaaaaaa aaaaaaaaaa                                      4230


<210>  1546
<211>  2088
<212>  DNA
<213>  homo sapiens

<400>  1546
ggtccgagtt cggaatttcg gttcaaggcc cagttcctcg gattgttcct gcgcaacttc       60

agtttccctt ccaggcacgg gcaatgagtg tttggccgcg acgagttgga aagcccggat      120

gcgtccttcg gttgggcggg gtgtctcagt gacgtcactg ggggtataaa agggcctggg      180

tggcgggcgc ctgggcagag cgtcctagca gtgtcactgc gtgggttggt ttgtgtagag      240

aggcgtgagc gagcccgttg tccggagtgc acctgctgcc tgttctgtcc ctcccgggag      300

cccccgccgc tgtcgccgtc gagtcgccat ggaagtgcag aaagaggcac agcgcatcat      360

gaccctgtcg gtgtggaaga tgtatcactc ccgcatgcag cgcggtggcc tgcggctgca      420

ccggagtctg cagctgtcgc tggtcatgcg cagcgcccgg gagctctacc tctcggccaa      480

ggtggaggcc ctcgagcccg aggtgtcgtt gccggccgcc ctcccctctg accctcgcct      540

gcacccgccc cgagaagccg agtccacggc cgagacagcg acccccgacg gtgagcaccc      600

gtttccggag ccaatggaca cgcaggaggc gccgacagcc gaggagacct ccgcctgctg      660

tgccccgcgc cccgccaaag tcagccgcaa acgacgcagc agcagcctga gcgacggcgg      720

ggacgctgga ctggtcccga gcaagaaagc ccgtctggaa gaaaaggaag aagaggaggg      780

agcgtcatcc gaagtcgccg atcgcctgca gccccctccg gcgcaagcgg agggcgcctt      840

tcccaacctg gcccgcgtcc tgcagaggcg cttctccggc ctcctgaact gcagccccgc      900

ggcccctccg acggcgccgc ccgcgtgcga ggcaaagccc gcttgccgcc cggcggacag      960

catgctcaac gtgctcgtgc gggccgtggt ggccttctga ggaccccgag cggcgctgcc     1020

ggagcccaga gcgcgcgtcg aaccgtcggc ccgagggcgc agacctgagg cgaggccacc     1080

cccctccatc ctgggggaag cgcccgcgaa aaccgtggag agaagccgcc gcccgggctg     1140

ctgagaggcc cggagaggga ctctgtcccc ggggagccat cgccttcagt gtgcagggac     1200

ggcaccgagg agtctgagcc gggggcgcgg gcgccttccg cagagacctg cgcccacagg     1260

tgctgtctta gtggactggg acgtgaacct ttcgctctcc ttctggactg ggagaaggga     1320

ggcttgggtg ttgtgttttt tgttttgttt gtttgtttgt ttttaaagat ctcctcaggg     1380

tcggacttca ttttgtactg tgggctgtgc tggccctttc aaggtttttc aagagttggt     1440

tttgcgtttc caacctcgga gaattccagg cactcccctt ccccctccgc tgacatactt     1500

gtataagcgg tcatcgttgc gtcatggggc aggcgtgggg agcttcctgt cgccttgcgt     1560

gggtgtgggg cctgggagga ggtcctgggg cgtgcacccg ccctgggcag tggggaggag     1620

agtggcctga gttacttcac ccccgcgtgc tgctggttaa tgtcccgcgt ctctgcacct     1680

tcgggtggga gcggggactg atctactttc acattctcaa gtttttctca tctgcattag     1740

aggtgcccag taggttccca ggttccagcg tgcccctccc tcagacacac ggacacaatc     1800

agccgagaag ttcctggtct gaatcacgag aatgtggagg ggtggggggt gtcagtggaa     1860

aggcataagg ctgagctgag accagttgct ggtgaaactg ggccaatctg gggaggggaa     1920

catccttgcc agggagtttc tgagggtctg ctttgtttac ctttcgtgcg gtggattctt     1980

tttaactccg tctacctggc gttttgttag aaatgtcaga taggaaaata aaaaccattt     2040

gagtaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                  2088


<210>  1547
<211>  2088
<212>  DNA
<213>  homo sapiens

<400>  1547
ggtccgagtt cggaatttcg gttcaaggcc cagttcctcg gattgttcct gcgcaacttc       60

agtttccctt ccaggcacgg gcaatgagtg tttggccgcg acgagttgga aagcccggat      120

gcgtccttcg gttgggcggg gtgtctcagt gacgtcactg ggggtataaa agggcctggg      180

tggcgggcgc ctgggcagag cgtcctagca gtgtcactgc gtgggttggt ttgtgtagag      240

aggcgtgagc gagcccgttg tccggagtgc acctgctgcc tgttctgtcc ctcccgggag      300

cccccgccgc tgtcgccgtc gagtcgccat ggaagtgcag aaagaggcac agcgcatcat      360

gaccctgtcg gtgtggaaga tgtatcactc ccgcatgcag cgcggtggcc tgcggctgca      420

ccggagtctg cagctgtcgc tggtcatgcg cagcgcccgg gagctctacc tctcggccaa      480

ggtggaggcc ctcgagcccg aggtgtcgtt gccggccgcc ctcccctctg accctcgcct      540

gcacccgccc cgagaagccg agtccacggc cgagacagcg acccccgacg gtgagcaccc      600

gtttccggag ccaatggaca cgcaggaggc gccgacagcc gaggagacct ccgcctgctg      660

tgccccgcgc cccgccaaag tcagccgcaa acgacgcagc agcagcctga gcgacggcgg      720

ggacgctgga ctggtcccga gcaagaaagc ccgtctggaa gaaaaggaag aagaggaggg      780

agcgtcatcc gaagtcgccg atcgcctgca gccccctccg gcgcaagcgg agggcgcctt      840

tcccaacctg gcccgcgtcc tgcagaggcg cttctccggc ctcctgaact gcagccccgc      900

ggcccctccg acggcgccgc ccgcgtgcga ggcaaagccc gcttgccgcc cggcggacag      960

catgctcaac gtgctcgtgc gggccgtggt ggccttctga ggaccccgag cggcgctgcc     1020

ggagcccaga gcgcgcgtcg aaccgtcggc ccgagggcgc agacctgagg cgaggccacc     1080

cccctccatc ctgggggaag cgcccgcgaa aaccgtggag agaagccgcc gcccgggctg     1140

ctgagaggcc cggagaggga ctctgtcccc ggggagccat cgccttcagt gtgcagggac     1200

ggcaccgagg agtctgagcc gggggcgcgg gcgccttccg cagagacctg cgcccacagg     1260

tgctgtctta gtggactggg acgtgaacct ttcgctctcc ttctggactg ggagaaggga     1320

ggcttgggtg ttgtgttttt tgttttgttt gtttgtttgt ttttaaagat ctcctcaggg     1380

tcggacttca ttttgtactg tgggctgtgc tggccctttc aaggtttttc aagagttggt     1440

tttgcgtttc caacctcgga gaattccagg cactcccctt ccccctccgc tgacatactt     1500

gtataagcgg tcatcgttgc gtcatggggc aggcgtgggg agcttcctgt cgccttgcgt     1560

gggtgtgggg cctgggagga ggtcctgggg cgtgcacccg ccctgggcag tggggaggag     1620

agtggcctga gttacttcac ccccgcgtgc tgctggttaa tgtcccgcgt ctctgcacct     1680

tcgggtggga gcggggactg atctactttc acattctcaa gtttttctca tctgcattag     1740

aggtgcccag taggttccca ggttccagcg tgcccctccc tcagacacac ggacacaatc     1800

agccgagaag ttcctggtct gaatcacgag aatgtggagg ggtggggggt gtcagtggaa     1860

aggcataagg ctgagctgag accagttgct ggtgaaactg ggccaatctg gggaggggaa     1920

catccttgcc agggagtttc tgagggtctg ctttgtttac ctttcgtgcg gtggattctt     1980

tttaactccg tctacctggc gttttgttag aaatgtcaga taggaaaata aaaaccattt     2040

gagtaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                  2088


<210>  1548
<211>  4322
<212>  DNA
<213>  homo sapiens

<400>  1548
gcgcatgcgc gaactcctgg cgggacctac gcggtagaag tttctactaa gtgaaaagga       60

agagcgaggg attcttttct ctgtggtcta cagcagcagc actattatta aaaatatttg      120

gaaagacaac ctggcaagtt ttgaaaaaga tttttttaaa aacggtaggg ttccgctcac      180

agtgggaggc ggggctcagt ggtccagaaa cgcctcttca gaagagggcg ggctcgccga      240

gaggcggggt ctcgggccca ctcggatgac gtgccgcgta gaagtatcgc gggaagagga      300

agggagcgta actcttagaa gtcactatgg tgacggggag gtaccaggta tttgagagca      360

atcgccaccg ctttcctgga acttgagtaa atacaatcaa gtggcatctt aaatttttgc      420

tggaagtgga gtcatgagac taaagatatc tcttttaaaa gaaccaaagc atcaagaatt      480

agtaagctgt gtgggctgga ctactgctga agagctgtat tcatgtagtg atgatcacca      540

gatagtgaag tggaacttgt taaccagtga aacaactcaa atagtaaagc ttcctgatga      600

tatttaccct attgattttc actggtttcc aaaaagtttg ggtgtaaaga aacaaaccca      660

ggcagaaagc tttgtcctca caagttctga tggtaaattt catctgattt ccaagttagg      720

aagagtggaa aaaagtgtag aagctcactg tggagcagta cttgcaggaa gatggaatta      780

tgaaggaaca gcattagtta cagttggaga agatggacaa ataaaaattt ggtcaaagac      840

tgggatgctt agatcaactt tagctcagca aggaacacca gtgtattcag tagcgtgggg      900

ccctgattca gaaaaggttc tttatacagc aggcaagcag ctaatcatta aacctcttca      960

accaaatgct aaagttttgc agtggaaagc tcatgatggc attattttaa aagtagattg     1020

gaactcggtc aatgatctta ttttatctgc tggtgaagac tgtaaatata aggtatggga     1080

tagttacggc cgcccactgt acaattcaca acctcatgag catcccatta cttcagttgc     1140

ctgggctcca gatggagaat tatttgctgt tggatcgttt catactttac gcttgtgtga     1200

taaaactggg tggtcatatg cattagaaaa acccaacact ggcagcatat ttaatattgc     1260

atggtctatc gatggcactc agattgctgg agcctgtgga aatggacatg tcgtttttgc     1320

acatgtggtg gaacaacatt gggagtggaa aaattttcaa gtaacattaa cgaaaagaag     1380

agccatgcag gttcgtaatg ttcttaatga tgcagtggat ttactggaat tccgtgatag     1440

agtcattaaa gcatctttga actatgcaca cttagttgtt tcaacgtctc ttcaatgtta     1500

cgtgttctcc acgaagaact ggaacacacc aattatattt gatctcaaag aaggaactgt     1560

tagtttgatt ctgcaggcag aaagacattt tcttcttgta gatggtagta gtatctattt     1620

atattcatat gaagggcgct ttatttcatc tccaaaattt cctggaatga gaacagatat     1680

tctgaatgca cagactgtgt ctttgagtaa tgataccata gcaataagag acaaagctga     1740

tgaaaaaata atcttcctct ttgaggcatc aaccggaaag ccgttaggtg atggaaagtt     1800

tctttctcat aagaatgaaa tcttggaaat tgctctggat caaaaaggac ttaccaatga     1860

tagaaaaatt gctttcattg ataaaaatag agatctctgt atcacttctg tgaaacgatt     1920

tgggaaggaa gaacaaatta tcaagcttgg aacaatggtg catactttgg catggaacga     1980

tacatgcaat atcctttgtg gacttcaaga tactcgattt atagtgtggt attaccccaa     2040

tacagtttat gtggacagag acattttgcc taaaacatta tatgaaaggg atgcaagtga     2100

atttagtaaa aatccccata ttgtgagttt tgttggaaat caagtaacta ttagaagagc     2160

tgatggctcc ctggttcaca tcagcataac accatatcct gctattctcc atgaatatgt     2220

aagcagttca aaatgggaag atgctgtgag actttgtcgc tttgttaagg agcaaaccat     2280

gtgggcttgt ctagctgcta tggcagttgc taatcgagat atgactactg cagaaatagc     2340

ctatgcagca attggtgaaa ttgataaggt tcagtacatc aattctataa aaaatcttcc     2400

atctaaagaa tcaaaaatgg cccacatact actgtttagt gggaacatac aggaggctga     2460

aatagtactt cttcaggctg gccttgttta tcaagcaatc cagatcaata ttaatctcta     2520

caactgggaa agggcactgg aattggctgt aaaatacaaa acacatgttg atacagttct     2580

tgcttaccgt caaaagtttt tggagacatt tggtaaacag gaaactaata aacgatactt     2640

gcattatgca gaaggtctcc aaatagattg ggagaaaatc aaagccaaaa ttgagatgga     2700

aattacaaaa gaaagagagc aatcatcaag cagccaatcc agcaagagta taggtttaaa     2760

gccctaaatg ccatgcgtat ctttaagaaa ttttatcttt tgaaacacgt tctgattaac     2820

caagggtaag catgttttgg ttgctaaaga aaaaagcata atctttaacc gagtataagt     2880

acttgctgtg tatttagtgt aaaagtacat gcagaaagat gaaacacaaa gtaattgatg     2940

tatttctatc ttttatattt tttagtccaa taattagcaa aatattacta tgtacttaag     3000

agatacctgt gtagtgtcga ttatatgtca gttttttgcc cattacttca tccctaaatc     3060

ttcagcatga acaaatatta atgtcgataa taaaacattg gactctttga aatgtatgtt     3120

accattaatt tctatttgac ctctaaattg taaaatgcct ccaaaagttt atttatagaa     3180

caaaaataca tgaggatgga tttgtacaaa tgtataaaat gccactattt atacaccaag     3240

ttcatagcag cattactgga atagcaaaag atggaaacag ctcaagtgtc tatcatgaat     3300

ggataaacaa atgtgctata atacatacaa tggaatatta tttagcttta aaaaggaatg     3360

aaattctgat aaatactacc tcaggataaa ccttgaaaac actatgctaa gtgaaataag     3420

ccagacacaa aaggccaaat atgatgccac ttttatgagg taccagcata ggcaagttca     3480

cagaaacaga aaggagaata gtggttgcca gggactgcag ggaggaggaa atggggggtg     3540

gggttattgt ttaacgagta catagtttct gtttgggatg aacaaattct ggaaatggat     3600

agcgatgatg gttgctcaac attttgaatg ttaatgccac taaattgtac ccataaaaat     3660

ggttaaaatg gtaaattttg ttatgtatat tttatcataa tttaaaaaat atatctagaa     3720

tgggcaagaa ggattctcct cattcctctc ttgacttgag aatgatcagt caataggccc     3780

tgaagtctga atttgtgaaa atttccttgg gtgacaaact tgtttgatta ctctatttag     3840

tgtatcccaa agttattacc acataatctt ttaaacaata aaacaaatac cccttagaaa     3900

gtcttctgca aacccatttc tgaaaatggt acattatagg gtgggtatag atgcatagat     3960

atgggattat gtatgatata tatatatata cacacacaca caaagggata gagagattac     4020

ctctcttaac ccccatttta attactatgt ctaggttttt taaataaaaa tcttttcttt     4080

ttaacatgtt tcttttcttt tccggaatat tggaatattc tgttcttgat ccagatgaaa     4140

tctgattgag cagtgtactt acaagttgta ctgtgtatgt gtttcctata ttgttatatt     4200

tcaataagaa gcttaaaatg tttaaaaata aatggttaaa aggttttatg ttatgtatat     4260

tttaccacaa taaatgcaaa aaataaaaag tctgtgttct aaacaaaaaa aaaaaaaaaa     4320

aa                                                                    4322


<210>  1549
<211>  5171
<212>  DNA
<213>  homo sapiens

<400>  1549
ggcgggagga gagtcggcgg ccggagccgt caccccgggc ggggacccag cgcaggcaac       60

tccgcgcggc ggcccggccg agggagggag cgagcgggcg ggcgggcaag ccagacagct      120

gggccggagc agccgcgggc gcccgagggg ccgagcgaga ttgtaaacca tggctgtgtg      180

gatacaagct cagcagctcc aaggagaagc ccttcatcag atgcaagcgt tatatggcca      240

gcattttccc attgaggtgc ggcattattt atcccagtgg attgaaagcc aagcatggga      300

ctcagtagat cttgataatc cacaggagaa cattaaggcc acccagctcc tggagggcct      360

ggtgcaggag ctgcagaaga aggcagagca ccaggtgggg gaagatgggt ttttactgaa      420

gatcaagctg gggcactatg ccacacagct ccagaacacg tatgaccgct gccccatgga      480

gctggtccgc tgcatccgcc atatattgta caatgaacag aggttggtcc gagaagccaa      540

caatggtagc tctccagctg gaagccttgc tgatgccatg tcccagaaac acctccagat      600

caaccagacg tttgaggagc tgcgactggt cacgcaggac acagagaatg agttaaaaaa      660

gctgcagcag actcaggagt acttcatcat ccagtaccag gagagcctga ggatccaagc      720

tcagtttggc ccgctggccc agctgagccc ccaggagcgt ctgagccggg agacggccct      780

ccagcagaag caggtgtctc tggaggcctg gttgcagcgt gaggcacaga cactgcagca      840

gtaccgcgtg gagctggccg agaagcacca gaagaccctg cagctgctgc ggaagcagca      900

gaccatcatc ctggatgacg agctgatcca gtggaagcgg cggcagcagc tggccgggaa      960

cggcgggccc cccgagggca gcctggacgt gctacagtcc tggtgtgaga agttggccga     1020

gatcatctgg cagaaccggc agcagatccg cagggctgag cacctctgcc agcagctgcc     1080

catccccggc ccagtggagg agatgctggc cgaggtcaac gccaccatca cggacattat     1140

ctcagccctg gtgaccagca cgttcatcat tgagaagcag cctcctcagg tcctgaagac     1200

ccagaccaag tttgcagcca ctgtgcgcct gctggtgggc gggaagctga acgtgcacat     1260

gaaccccccc caggtgaagg ccaccatcat cagtgagcag caggccaagt ctctgctcaa     1320

gaacgagaac acccgcaatg attacagtgg cgagatcttg aacaactgct gcgtcatgga     1380

gtaccaccaa gccacaggca cccttagtgc ccacttcagg aatatgtccc tgaaacgaat     1440

taagaggtca gaccgtcgtg gggcagagtc ggtgacagaa gaaaaattta caatcctgtt     1500

tgaatcccag ttcagtgttg gtggaaatga gctggttttt caagtcaaga ccctgtccct     1560

gccagtggtg gtgatcgttc atggcagcca ggacaacaat gcgacggcca ctgttctctg     1620

ggacaatgct tttgcagagc ctggcagggt gccatttgcc gtgcctgaca aagtgctgtg     1680

gccacagctg tgtgaggcgc tcaacatgaa attcaaggcc gaagtgcaga gcaaccgggg     1740

cctgaccaag gagaacctcg tgttcctggc gcagaaactg ttcaacaaca gcagcagcca     1800

cctggaggac tacagtggcc tgtctgtgtc ctggtcccag ttcaacaggg agaatttacc     1860

aggacggaat tacactttct ggcaatggtt tgacggtgtg atggaagtgt taaaaaaaca     1920

tctcaagcct cattggaatg atggggccat tttggggttt gtaaacaagc aacaggccca     1980

tgacctactc attaacaagc cagatgggac cttcctcctg agattcagtg actcagaaat     2040

tggcggcatc accattgctt ggaagtttga ttctcaggaa agaatgtttt ggaatctgat     2100

gccttttacc accagagact tctccattcg gtccctagcc gaccgcttgg gagacttgaa     2160

ttaccttatc tacgtgtttc ctgatcggcc aaaagatgaa gtatactcca aatactacac     2220

accagttccc tgcgagtctg ctactgctaa agctgttgat ggatacgtga agccacagat     2280

caagcaagtg gtccctgagt ttgtgaacgc atctgcagat gccgggggcg gcagcgccac     2340

gtacatggac caggccccct ccccagctgt gtgtccccag gctcactata acatgtaccc     2400

acagaaccct gactcagtcc ttgacaccga tggggacttc gatctggagg acacaatgga     2460

cgtagcgcgg cgtgtggagg agctcctggg ccggccaatg gacagtcagt ggatcccgca     2520

cgcacaatcg tgaccccgcg acctctccat cttcagcttc ttcatcttca ccagaggaat     2580

cactcttgtg gatgttttaa ttccatgaat cgcttctctt ttgaaacaat actcataatg     2640

tgaagtgtta atactagttg tgaccttagt gtttctgtgc atggtggcac cagcgaaggg     2700

agtgcgagta tgtgtttgtg tgtgtgtgtg tgtgtgtgtg tgtgtgcgtg tttgcacgtt     2760

atggtgtttc tccctctcac tgtctgagag tttagttgta gcagaggggc cacagacaga     2820

agctgtggtg gtttttactt tgtgcaaaaa ggcagtgagt ttcgtgaagc ctggaagttg     2880

gccatgtgtc ttaagagtgg ctggactttg acatgtggct gtttgaataa gagaaggaca     2940

aagggaggag aaagcacatg tgctccagtg agtcttcgtc actctgtctg ccaagcaatt     3000

gatatataac cgtgattgtc tctgcttttc ttctgaaatg tagataactg ctttttgaca     3060

aagagagcct tccctctccc ccacccctgt gttcttgggt aggaatggga aaaggggcaa     3120

cctacaaaga ttgttggggc aagggaagtc acaagctttc ggatgggcgg tggcttttca     3180

caaaacattt agctcatctt attctctctt tgtcctctct cccctcctgc ccgcccgcac     3240

cctggaattg ccactcagtt cctctgggtg tgcacatatg tttggagaaa tagaggagag     3300

aaaagagggc cacgtaactg agagcttaca gtgccaatgc cgtttgtgtt ctggccagag     3360

tggagtgcgc agccctgact cccaggcgct gagattgttg cctggttacc caggaagctg     3420

ctgttccggc tgcccagcct ttctctgagc cagcggatgc acagtccgtg gccttcttca     3480

ggcttattga tgatgctttt tgcaaatgtt gaatcatggt tctgtttcta agttggatct     3540

tttttgtttt ctccttgcca ccctaatttg acatcaaaat tctctcttgt gcattgggcc     3600

ctgggtcatt caaacccagg tcacctcatt ccccttctct gttcacacct aatgtcttga     3660

agagtaggta gcagcagtgt gggctgaacc taggccagct tgcttagcgg gtcaccctgc     3720

tgtgaagtcc tggcaggtgt tggtaatgtg tggaaatgca gtcagcaagt ttgctgggga     3780

gtttgataaa agtataaaac aaaacaaaaa aagcctcggt ataattttgt tccacgactt     3840

cttctgtagc tttacaccag aaggaaggaa tgggctacag caggtagtgg aggaagaggg     3900

gggtgagcag gtgtattaaa atagcttacg ggtaaggcct aaaaggtcac ccctcggccc     3960

cctctccaaa agaagggcat gggcaccccc aggagaggat ggccccaaaa accttatttt     4020

tatacatgag agtaaataaa catatttttt ttacaaaaat aacttctgaa tttatcagtg     4080

ttttgccgtt aaaaatattc ctctatagta aattatttat tggaagatga cttttttaaa     4140

gctgccgttt gccttggctt ggtttcatac actgatttat ttttctatgc caggcagtag     4200

agtctctctg cctctgagga gcaggctacc cgcatcccac tcagcccctc cctacccctc     4260

aagatttgat gaaaattcca accatgagga tgggtgcatc ggggaagggt gagaaggaga     4320

gcctgcctgc tcagggatcc aggctcgtag agtcactccc tgcccgtctc ccagagatgc     4380

ttcaccagca cctgcctctg agacctcgct ctctgttcca gcaaccctgg ttggggggtc     4440

agacttgata cactttcagg ttgggagtgg acccacccca gggcctgctg aggacagagc     4500

agccaggccg tcctggctca ctttgcagtt ggcactgggt tggggaggaa gagagctgat     4560

gagtgtggct tccctgagct ggggtttccc tgcttgtcca gttgtgagct gtcctcggtg     4620

ttaccgaggc tgtgcctaga gagtggagat ttttgatgaa aggtgtgctc gctctctgcg     4680

ttctatcttc tctctcctcc ttgttcctgc aaaccacaag ataaaggtag tggtgtgtct     4740

cgaccccatc agcctctcac ccactcccag acacacacaa gtcctcaaaa gtttcagctc     4800

cgtgtgtgag atgtgcaggt tttttctagg gggtaggggg agactaaaat cgaatataac     4860

ttaaaatgaa agtatacttt ttataatttt tctttttaaa acttggtgaa attatttcag     4920

atacatattt tagtgtcaag gcagattagt tatttagcca ccaaaaaaaa gtattgtgta     4980

caatttgggg cctcaaattt gactctgcct caaaaaaaag aaatatatcc tatgcagagt     5040

tacagtcaca aagttgtgta ttttatgtta caataaagcc ttcctctgaa gggaaaaaaa     5100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     5160

aaaaaaaaaa a                                                          5171


<210>  1550
<211>  5171
<212>  DNA
<213>  homo sapiens

<400>  1550
ggcgggagga gagtcggcgg ccggagccgt caccccgggc ggggacccag cgcaggcaac       60

tccgcgcggc ggcccggccg agggagggag cgagcgggcg ggcgggcaag ccagacagct      120

gggccggagc agccgcgggc gcccgagggg ccgagcgaga ttgtaaacca tggctgtgtg      180

gatacaagct cagcagctcc aaggagaagc ccttcatcag atgcaagcgt tatatggcca      240

gcattttccc attgaggtgc ggcattattt atcccagtgg attgaaagcc aagcatggga      300

ctcagtagat cttgataatc cacaggagaa cattaaggcc acccagctcc tggagggcct      360

ggtgcaggag ctgcagaaga aggcagagca ccaggtgggg gaagatgggt ttttactgaa      420

gatcaagctg gggcactatg ccacacagct ccagaacacg tatgaccgct gccccatgga      480

gctggtccgc tgcatccgcc atatattgta caatgaacag aggttggtcc gagaagccaa      540

caatggtagc tctccagctg gaagccttgc tgatgccatg tcccagaaac acctccagat      600

caaccagacg tttgaggagc tgcgactggt cacgcaggac acagagaatg agttaaaaaa      660

gctgcagcag actcaggagt acttcatcat ccagtaccag gagagcctga ggatccaagc      720

tcagtttggc ccgctggccc agctgagccc ccaggagcgt ctgagccggg agacggccct      780

ccagcagaag caggtgtctc tggaggcctg gttgcagcgt gaggcacaga cactgcagca      840

gtaccgcgtg gagctggccg agaagcacca gaagaccctg cagctgctgc ggaagcagca      900

gaccatcatc ctggatgacg agctgatcca gtggaagcgg cggcagcagc tggccgggaa      960

cggcgggccc cccgagggca gcctggacgt gctacagtcc tggtgtgaga agttggccga     1020

gatcatctgg cagaaccggc agcagatccg cagggctgag cacctctgcc agcagctgcc     1080

catccccggc ccagtggagg agatgctggc cgaggtcaac gccaccatca cggacattat     1140

ctcagccctg gtgaccagca cgttcatcat tgagaagcag cctcctcagg tcctgaagac     1200

ccagaccaag tttgcagcca ctgtgcgcct gctggtgggc gggaagctga acgtgcacat     1260

gaaccccccc caggtgaagg ccaccatcat cagtgagcag caggccaagt ctctgctcaa     1320

gaacgagaac acccgcaatg attacagtgg cgagatcttg aacaactgct gcgtcatgga     1380

gtaccaccaa gccacaggca cccttagtgc ccacttcagg aatatgtccc tgaaacgaat     1440

taagaggtca gaccgtcgtg gggcagagtc ggtgacagaa gaaaaattta caatcctgtt     1500

tgaatcccag ttcagtgttg gtggaaatga gctggttttt caagtcaaga ccctgtccct     1560

gccagtggtg gtgatcgttc atggcagcca ggacaacaat gcgacggcca ctgttctctg     1620

ggacaatgct tttgcagagc ctggcagggt gccatttgcc gtgcctgaca aagtgctgtg     1680

gccacagctg tgtgaggcgc tcaacatgaa attcaaggcc gaagtgcaga gcaaccgggg     1740

cctgaccaag gagaacctcg tgttcctggc gcagaaactg ttcaacaaca gcagcagcca     1800

cctggaggac tacagtggcc tgtctgtgtc ctggtcccag ttcaacaggg agaatttacc     1860

aggacggaat tacactttct ggcaatggtt tgacggtgtg atggaagtgt taaaaaaaca     1920

tctcaagcct cattggaatg atggggccat tttggggttt gtaaacaagc aacaggccca     1980

tgacctactc attaacaagc cagatgggac cttcctcctg agattcagtg actcagaaat     2040

tggcggcatc accattgctt ggaagtttga ttctcaggaa agaatgtttt ggaatctgat     2100

gccttttacc accagagact tctccattcg gtccctagcc gaccgcttgg gagacttgaa     2160

ttaccttatc tacgtgtttc ctgatcggcc aaaagatgaa gtatactcca aatactacac     2220

accagttccc tgcgagtctg ctactgctaa agctgttgat ggatacgtga agccacagat     2280

caagcaagtg gtccctgagt ttgtgaacgc atctgcagat gccgggggcg gcagcgccac     2340

gtacatggac caggccccct ccccagctgt gtgtccccag gctcactata acatgtaccc     2400

acagaaccct gactcagtcc ttgacaccga tggggacttc gatctggagg acacaatgga     2460

cgtagcgcgg cgtgtggagg agctcctggg ccggccaatg gacagtcagt ggatcccgca     2520

cgcacaatcg tgaccccgcg acctctccat cttcagcttc ttcatcttca ccagaggaat     2580

cactcttgtg gatgttttaa ttccatgaat cgcttctctt ttgaaacaat actcataatg     2640

tgaagtgtta atactagttg tgaccttagt gtttctgtgc atggtggcac cagcgaaggg     2700

agtgcgagta tgtgtttgtg tgtgtgtgtg tgtgtgtgtg tgtgtgcgtg tttgcacgtt     2760

atggtgtttc tccctctcac tgtctgagag tttagttgta gcagaggggc cacagacaga     2820

agctgtggtg gtttttactt tgtgcaaaaa ggcagtgagt ttcgtgaagc ctggaagttg     2880

gccatgtgtc ttaagagtgg ctggactttg acatgtggct gtttgaataa gagaaggaca     2940

aagggaggag aaagcacatg tgctccagtg agtcttcgtc actctgtctg ccaagcaatt     3000

gatatataac cgtgattgtc tctgcttttc ttctgaaatg tagataactg ctttttgaca     3060

aagagagcct tccctctccc ccacccctgt gttcttgggt aggaatggga aaaggggcaa     3120

cctacaaaga ttgttggggc aagggaagtc acaagctttc ggatgggcgg tggcttttca     3180

caaaacattt agctcatctt attctctctt tgtcctctct cccctcctgc ccgcccgcac     3240

cctggaattg ccactcagtt cctctgggtg tgcacatatg tttggagaaa tagaggagag     3300

aaaagagggc cacgtaactg agagcttaca gtgccaatgc cgtttgtgtt ctggccagag     3360

tggagtgcgc agccctgact cccaggcgct gagattgttg cctggttacc caggaagctg     3420

ctgttccggc tgcccagcct ttctctgagc cagcggatgc acagtccgtg gccttcttca     3480

ggcttattga tgatgctttt tgcaaatgtt gaatcatggt tctgtttcta agttggatct     3540

tttttgtttt ctccttgcca ccctaatttg acatcaaaat tctctcttgt gcattgggcc     3600

ctgggtcatt caaacccagg tcacctcatt ccccttctct gttcacacct aatgtcttga     3660

agagtaggta gcagcagtgt gggctgaacc taggccagct tgcttagcgg gtcaccctgc     3720

tgtgaagtcc tggcaggtgt tggtaatgtg tggaaatgca gtcagcaagt ttgctgggga     3780

gtttgataaa agtataaaac aaaacaaaaa aagcctcggt ataattttgt tccacgactt     3840

cttctgtagc tttacaccag aaggaaggaa tgggctacag caggtagtgg aggaagaggg     3900

gggtgagcag gtgtattaaa atagcttacg ggtaaggcct aaaaggtcac ccctcggccc     3960

cctctccaaa agaagggcat gggcaccccc aggagaggat ggccccaaaa accttatttt     4020

tatacatgag agtaaataaa catatttttt ttacaaaaat aacttctgaa tttatcagtg     4080

ttttgccgtt aaaaatattc ctctatagta aattatttat tggaagatga cttttttaaa     4140

gctgccgttt gccttggctt ggtttcatac actgatttat ttttctatgc caggcagtag     4200

agtctctctg cctctgagga gcaggctacc cgcatcccac tcagcccctc cctacccctc     4260

aagatttgat gaaaattcca accatgagga tgggtgcatc ggggaagggt gagaaggaga     4320

gcctgcctgc tcagggatcc aggctcgtag agtcactccc tgcccgtctc ccagagatgc     4380

ttcaccagca cctgcctctg agacctcgct ctctgttcca gcaaccctgg ttggggggtc     4440

agacttgata cactttcagg ttgggagtgg acccacccca gggcctgctg aggacagagc     4500

agccaggccg tcctggctca ctttgcagtt ggcactgggt tggggaggaa gagagctgat     4560

gagtgtggct tccctgagct ggggtttccc tgcttgtcca gttgtgagct gtcctcggtg     4620

ttaccgaggc tgtgcctaga gagtggagat ttttgatgaa aggtgtgctc gctctctgcg     4680

ttctatcttc tctctcctcc ttgttcctgc aaaccacaag ataaaggtag tggtgtgtct     4740

cgaccccatc agcctctcac ccactcccag acacacacaa gtcctcaaaa gtttcagctc     4800

cgtgtgtgag atgtgcaggt tttttctagg gggtaggggg agactaaaat cgaatataac     4860

ttaaaatgaa agtatacttt ttataatttt tctttttaaa acttggtgaa attatttcag     4920

atacatattt tagtgtcaag gcagattagt tatttagcca ccaaaaaaaa gtattgtgta     4980

caatttgggg cctcaaattt gactctgcct caaaaaaaag aaatatatcc tatgcagagt     5040

tacagtcaca aagttgtgta ttttatgtta caataaagcc ttcctctgaa gggaaaaaaa     5100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     5160

aaaaaaaaaa a                                                          5171


<210>  1551
<211>  7221
<212>  DNA
<213>  homo sapiens

<400>  1551
cactcgctct ctccctctgt gtatagagga tgtgctgaat ggtgcgcttt gaggcggcgg       60

cggcggagga gcagaatccg ccgcgactgg cagcctcggc tgaccggctc ggcttctctt      120

cgccttccga ggctcctcat ccaccgcggg ctccagacct cgcgtcccgc ccggggcatg      180

gccgggcgct gcgcccccgc gcgctctgcc tgctgagcgg cgccggaggg aggtgcggag      240

gccgggaggc cggggaggcc ggcggggagc agagtcgagc gcctccggag cagagaaagg      300

agcccgcgcc ccgcgccccg cgccccgcgc acggtcccca gtccctgccg cgctcgcccg      360

ggccgcccgg agcccagatg agcccagatg gccggggctc aacccggagt gcacgccttg      420

caactcaagc ccgtgtgcgt gtccgacagc ctcaagaagg gcaccaaatt cgtcaagtgg      480

gatgatgact caactattgt tactccaatt attttgagga ctgaccctca gggatttttc      540

ttttactgga cagatcaaaa caaggagaca gagctactgg atctcagcct tgtcaaagat      600

gccagatgtg ggagacacgc caaagctccc aaggacccca aattacgtga acttttggat      660

gtggggaaca tcgggcgcct ggagcagcgc atgatcacag tggtgtatgg gcctgacctc      720

gtgaacatct cccatttgaa tctcgtggct ttccaagaag aagtggccaa ggaatggaca      780

aatgaggttt tcagtttggc aacaaacctg ctggcccaaa acatgtccag ggatgcattt      840

ctggaaaaag cctatactaa acttaagctg caagtcactc cagaagggcg tattcctctc      900

aaaaacatat atcgcttgtt ttcagcagat cggaagcgag ttgaaactgc tttagaggct      960

tgtagtcttc catcttcaag gaatgattca atacctcaag aagatttcac tccagaagtg     1020

tacagagttt tcctcaacaa cctttgccct cgacctgaaa ttgataacat cttttcagaa     1080

tttggtgcaa aaagcaaacc atatcttacc gttgatcaga tgatggattt tatcaacctt     1140

aagcagcgag atcctcggct taatgaaata ctttatccac ctctaaaaca agagcaagtc     1200

caagtattga ttgagaagta tgaacccaac aacagcctcg ccagaaaagg acaaatatca     1260

gtggatgggt tcatgcgcta tctgagtgga gaagaaaacg gagtcgtttc acctgagaaa     1320

ctggatttga atgaagacat gtctcagccc ctttctcact atttcattaa ttcctcgcac     1380

aacacctacc tcacagctgg ccaactggct ggaaactcct ctgttgagat gtatcgccaa     1440

gtgctcctgt ctggttgtcg ctgtgtggag ctggactgct ggaagggacg gactgcagaa     1500

gaggaacctg tcatcaccca tggcttcacc atgacaactg aaatatcttt caaggaagtg     1560

atagaagcaa ttgcggagtg tgcatttaag acttcacctt ttccaattct cctttcgttt     1620

gagaaccatg tggattcccc aaagcagcaa gccaagatgg cggagtactg ccgactgatc     1680

tttggggatg cccttctcat ggagcccctg gaaaaatatc cactggaatc tggagttcct     1740

cttccaagcc ctatggattt aatgtataaa attttggtga aaaataagaa gaaatcacac     1800

aagtcatcag aaggaagcgg caaaaagaag ctctcagaac aagcctccaa cacctacagt     1860

gactcctcca gcatgttcga gccctcatcc ccaggagccg gagaagctga tacggaaagt     1920

gacgacgacg atgatgatga tgactgtaaa aaatcttcaa tggatgaggg gactgctgga     1980

agtgaggcta tggccacaga agaaatgtct aatctggtga actatattca gccagtcaag     2040

tttgagtcat ttgaaatttc aaaaaaaaga aataaaagtt ttgaaatgtc ttccttcgtg     2100

gaaaccaaag gacttgaaca actcaccaag tctccagtgg aatttgtaga atataacaaa     2160

atgcagctta gcaggatata tccaaaagga acacgtgtgg attcatccaa ctatatgcct     2220

cagctcttct ggaatgcagg ttgtcagatg gtggcactta atttccagac aatggacctg     2280

gctatgcaaa taaatatggg gatgtatgaa tacaacggga agagtggcta cagattgaag     2340

ccagagttca tgaggaggcc tgacaagcat tttgatccat ttactgaagg catcgtagat     2400

gggatagtgg caaacacttt gtctgttaag attatttcag gtcagtttct ttctgataag     2460

aaagttggga cttacgtgga agtagatatg tttggtttgc ctgtggatac aaggaggaag     2520

gcatttaaga ccaaaacatc ccaaggaaat gctgtgaatc ctgtctggga agaagaacct     2580

attgtgttca aaaaggtggt tcttcctact ctggcctgtt tgagaatagc agtttatgaa     2640

gaaggaggta aattcattgg ccaccgtatc ttgccagtgc aagccattcg gccaggctat     2700

cactatatct gtctaaggaa tgaaaggaac cagcctctga cgctgcctgc tgtctttgtc     2760

tacatagaag tgaaagacta tgtgccagac acatatgcag atgtcatcga agctttatca     2820

aacccaatcc gatatgtgaa cctgatggaa cagagagcta agcaattggc tgctttgaca     2880

ctggaagatg aagaagaagt aaagaaagag gctgatcctg gagaaacacc atcagaggct     2940

ccaagtgaag cgagaacgac tccagcagaa aatggggtga atcacactac aaccctgaca     3000

cccaagccac cctcccaggc tctccacagc cagccagctc caggttctgt aaaggcacct     3060

gccaaaacag aagatcttat tcagagtgtc ttaacagaag tggaagcaca gaccatcgaa     3120

gaactaaagc aacagaaatc gtttgtgaaa cttcaaaaga aacactacaa agaaatgaaa     3180

gacctggtta agagacacca caagaaaacc actgacctta tcaaagaaca cactaccaag     3240

tataatgaaa ttcagaatga ctacttgaga aggagagccg ctttggaaaa gtccgccaaa     3300

aaggacagta agaaaaaatc ggaacccagc agccctgatc atggttcatc aacgattgag     3360

caagacctcg ctgctctgga tgctgaaatg acccaaaagt taatagactt gaaggacaaa     3420

caacagcagc agctgcttaa tcttcggcaa gaacagtatt atagtgaaaa ataccagaag     3480

cgagaacata ttaaactgct tattcaaaag ttgacggatg tcgcagaaga gtgtcagaac     3540

aatcagttaa agaagctcaa agaaatctgt gagaaagaaa agaaagaatt aaagaagaaa     3600

atggataaaa agaggcagga gaagataaca gaagctaaat ccaaagacaa aagtcagatg     3660

gaagaggaga agacagagat gatccggtca tatatccagg aagtggtgca gtatatcaag     3720

aggctagaag aagcgcaaag taaacggcaa gaaaaactcg tagagaaaca caaggaaata     3780

cgtcagcaga tcctggatga aaagcccaag ggggaaggtt cctcctcatt cttgtcggaa     3840

acttgccatg aggatccctc tgtttccccc aactttactc cccccaaccc tcaagctctc     3900

aagtggtgac caccgtcctt ccggccagct gcaggtggag ctggagcaag aataccaaga     3960

caaattcaaa agactgcccc tcgagatttt ggaattcgtg caggaagcca tgaaaggaaa     4020

gatcagtgaa gacagcaatc acggttctgc ccctctctcc ctgtcctcag accctggaaa     4080

agtgaaccac aagactccct ccagtgagga gctgggagga gacatcccag gaaaagaatt     4140

tgatactcct ctgtgaatgc tcctgccagg ccttcagaaa ttgcatggcc actccagcgt     4200

catcggactc tctcttatta caaagatcac tgcccaggac catcttcccg agaagcatcc     4260

cttagcctaa aatccacacc aaagggagag ttccagagga atccatgaag aattcccatg     4320

cccaggctcc atgtgtcatg tggaaacctc cacaggtctg ctagtgaaga atgcatgtat     4380

gtgagatttt tgttttcttt ccaatagcaa attcaaagca agcaacttgc aggctccatg     4440

gaacttttaa tgaaggacag tgtcttcttt gaagaaaatc aagctcgtgt ttttattcga     4500

agctctggtg taaaatattt caaagtcata gaaatagttt gagaaatgca tagcattatt     4560

taacactatt gaacagccga ctttgagcat tgtttcttct aactgcccct caactaccat     4620

tatcttcaag tcaacatgca tattacattt tcatcctttg ctttgcaagc actggtggct     4680

tgcagtttgc taatttattt atcatagagt catcaatgta tttgttgctg acatggtttt     4740

attagatact gtagtgattc aaataagttt tctatttgaa aaaaaaaatc acttgattgt     4800

atccttgccc agtgaagcca tcctaagact tagcaatatg gattgtacat ttggctgcat     4860

gagcaagtcg gccgcacact tccagacagt gtgctgtttg aattgactat ttgcactcaa     4920

agtctgggta ttcattggtt attggcctga aatgatcaaa taactacaaa tgatctgttg     4980

aataaaaata gttgagctga tatatgttaa gcagatattc aatcagaatg aacaggttcc     5040

ggtggttatt ttgccgtttg acatttttta tggttcattt atttttaata tagagaggaa     5100

gattgaatat ttatctagag aatacaaaga cccacatgta aatgataggt attatctcca     5160

tgtatatatg tacccactta gtcatgtaag tgcatataca catacacaca catgagtgta     5220

gacatgtgtt tattaattga caatgaccca aatctcttcc acaagactta aaaccaaatt     5280

cagggacaaa tggatagaga agaaaagggt caaacatcga gattacatgg atgttaaatt     5340

atatggagac gctaagaaat aattgatgga gccattgatg caaaccgaag tagatttaga     5400

acttatatga atttgattta tattttgcaa gatcaaaaat tagatgttaa gtatcagatt     5460

ttaagcttgt tttaatggtc aaaaaattag gacagaaata atatggacat ttattagtat     5520

cttccataat ttttaagtct gacacatttc tattttattc taacataaaa aaacttccat     5580

tatatattta ctaagtatat ttaattcact taactctgtc tttataagtt cctattttag     5640

atggaataag agaaacaaat tatatcaagg taaaactgat caaaagcata attgaaagtt     5700

ctgaaaaaag aaaaataata atatgtagaa aaatgtaact tagagagtaa cacatgaaca     5760

ttgaagttaa aacccagaag ccagatgctc acagttttat tttactttaa aataaacctg     5820

tctgactgta gctttgtgaa atatcttaaa acgcaaaaac caattgtgtc ctgaaaattg     5880

tttcaagaat ttaatatttt tatgaaaatt attttattta actttaagca ataactagag     5940

attacaatta aattttaatc aaaatgaagg cttagttcaa acataaggaa acagtgtttg     6000

attaaaaaaa acacatctag taagacgtaa ggggaaaatc acatcctctt tggagatgat     6060

tatattttga tctgaagggt ttggggtgtt cattagacac ttaataaaac ttaacttcca     6120

atgaaaaaga aatcttttgt aaatcattct acttttgcac tttgaaagaa aggcgttaat     6180

cataaagaag caagaatggt caaaatcgaa tgctgcattt ttataaacaa aattacagac     6240

tgtctgaaat tgaagaagaa tgaactaata atagcattca taaccaaaca caatgatgat     6300

tattgcagaa cattgtatca cattttagtc cagagataga ataaagttga ataaccttga     6360

cttacacaaa actgttttgg tagttggatt tcattatctt agtgaattta gtcattttac     6420

aatatgtttg tatttggcca tttactgtaa tcacattttt atatctgtac aatgacactt     6480

tttgcagttg tggggtagtg tgtaacactg tccatcttgc atcattgaaa ctactacaat     6540

gatactatca tttaataata ttaatattac ttgaaataga ctaagataaa gaaaaggggt     6600

ctgtatgatg tgcagttttg tgcctttatg tatttgcctt gttctttgtc gaatgtgtga     6660

aattccgtac tgtggttttt cctataatag aaagtagagc tgtgtattaa attagactgt     6720

gtctctctga tacctttaca ctactgagaa tagcatggtt ttggccatgt aaaccaattt     6780

tcaaagttct aatgacatag ccatgtgttt ttggtttttt atatttcatt ttaaaatttg     6840

agtatcacca tacattaatt aatactcctg tagtagataa gctgtcatta agtaattccc     6900

aaaaaaaggg ccatttgctt gcattacttt gaatttaatg ttgcgcttgt gcactgtgtt     6960

aatattgttt gtgatggatt ggacgttgtg actcttgcct tttaagaaga aaaaaaagat     7020

aggacaaagt atttgaagct cttaaaatgt acatattttg gttcttctat ctcaaattat     7080

ttaaaatgca taattcacat ttttgtaata attctatgca attttgtggc atgatgtttc     7140

ttccacttgt aattttatgt gctttcatca caaatccaaa ggaaagaata aaaatttctt     7200

aacacaaaaa aaaaaaaaaa a                                               7221


<210>  1552
<211>  1546
<212>  DNA
<213>  homo sapiens

<400>  1552
gattgtggga aggcagctga actcggcgcc tggaaagatg gaggcagcgg agacagaggc       60

ggaagctgca gccctagagg tcctggctga ggtggcaggc atcttggaac ctgtaggcct      120

gcaggaggag gcagaactgc cagccaagat cctggttgag tttgtggtgg actctcagaa      180

gaaagacaag ctgctctgca gccagcttca ggtagcggat ttcctgcaga acatcctggc      240

tcaggaggac actgctaagg gtctcgaccc cttggcttct gaagacacga gccgacagaa      300

ggcaattgca gctaaggaac aatggaaaga gctgaaggcc acctacaggg agcacgtaga      360

ggccatcaaa attggcctca ccaaggccct gactcagatg gaggaagccc agaggaaacg      420

gacacaactc cgggaagcct ttgagcagct ccaggccaag aaacaaatgg ccatggagaa      480

acgcagagca gtccagaacc agtggcagct acaacaggag aagcatctgc agcatctggc      540

ggaggtttct gcagagggta agctgttgtt ccctgaggct gaggctgagg cagagaatct      600

tccagatgat aaaccccagc agccgactcg accccaggag cagagtacag gagacaccat      660

ggggagagac cctggtgtgt ccttcaaggc tgttggtcta caacctgctg gagatgtaaa      720

tttgccatga cttcctggag gacagcagca tggagaaaga tcctagaaaa ggcctctgac      780

ttccctcacc tcccaaccat cattacagga aagactgtga actcctgagt tcagcttgat      840

ttctgactac atcccagcaa gctctggcat ctgtggatta aaatccctgg atctctctca      900

gttgtgtatt tgttcatctt catatgctgg caggaacaac tattaataca gatactcaga      960

agccaataac atgacaggag ctgggactgg tttgaacaca gggtgtgcag atggggaggg     1020

ggtactggcc ttgggcctcc tatgatgcag acatggtgaa tttaattcaa ggaggaggag     1080

aatgttttag gcaggtggtt atatgtggga agataatttt attcatggat ccaaatgttt     1140

gttgagtcct ttctttgtgc taaggttctt gcggtgaacc agaattataa cagtgagctc     1200

atctgactgt tttaggatgt acagcctagt gttaacattc ttggtatctt tttgtgcctt     1260

atctaaaaca tttctcgatc actggtttca gatgttcatt tattatattc ttttcaaaga     1320

ttcagagatt ggcttttgtc atccactatt gtatgttttg tttcattgac ctctagtgat     1380

accttgatct ttcccacttt ctgttttcgg attggagaag atgtaccttt tttgtcaact     1440

cttactttta tcagatgatc aactcacgta tttggatctt tatttgtttt ctcaaataaa     1500

tatttaaggt tatacattta aaaaaaaaaa aaaaaaaaaa aaaaaa                    1546


<210>  1553
<211>  7233
<212>  DNA
<213>  homo sapiens

<400>  1553
agctgcaagt tgggctgcag gggcagcgca tacactacaa tggctgctgg aaagaggcgt       60

aaggaaacaa tttccaggcc cgccgcgtcc agcccgaaat atgagaaaaa aattattaga      120

aattccgcgg gcggtgtaga ggcggcggac gggccggagg gaggatgtta aagccccgcg      180

attggccaaa atgggaagga ttggattcca ctctcttcca cgaagagtca atgggactgg      240

ctaagatcaa agtctgaggc tttttccatc agtaatcagt ccctttttgc tttcttttac      300

gaccacatga aacttgagaa gccacctaaa gctatatcat ttagtggagt tgggcagttc      360

ccaagtgtcc aacaagaagg cctggtttag gctgcgatgg ccactgtcat tcctggtgat      420

ttgtcagaag taagagatac ccagaaagtc ccttcaggga aacgtaagcg tggtgaaacc      480

aaaccaagaa aaaactttcc ttgccaactg tgtgacaagg cctttaacag tgttgagaaa      540

ttaaaggttc actcctactc tcacacagga gagaggccct acaagtgcat acaacaagac      600

tgcaccaagg cctttgtttc taagtacaaa ttacaaaggc acatggctac tcattctcct      660

gagaaaaccc acaagtgtaa ttattgtgag aaaatgtttc accggaaaga tcatctgaag      720

aatcacctcc atacacacga ccctaacaaa gagacgttta agtgcgaaga atgtggcaag      780

aactacaata ccaagcttgg atttaaacgt cacttggcct tgcatgccgc aacaagtggt      840

gacctcacct gtaaggtatg tttgcaaact tttgaaagca cgggagtgct tctggagcac      900

cttaaatctc atgcaggcaa gtcgtctggt ggggttaaag aaaaaaagca ccagtgcgaa      960

cattgtgatc gccggttcta cacccgaaag gatgtccgga gacacatggt ggtgcacact     1020

ggaagaaagg acttcctctg tcagtattgt gcacagagat ttgggcgaaa ggatcacctg     1080

actcgacata tgaagaagag tcacaatcaa gagcttctga aggtcaaaac agaaccagtg     1140

gatttccttg acccatttac ctgcaatgtg tctgtgccta taaaagacga gctccttccg     1200

gtgatgtcct taccttccag tgaactgtta tcaaagccat tcacaaacac tttgcagtta     1260

aacctctaca acactccatt tcagtccatg cagagctcgg gatctgccca ccaaatgatc     1320

acaactttac ctttgggaat gacatgccca atagatatgg acactgttca tccctctcac     1380

cacctttctt tcaaatatcc gttcagttct acctcatatg caatttctat tcctgaaaaa     1440

gaacagccat taaaggggga aattgagagt tacctgatgg agttacaagg tggcgtgccc     1500

tcttcatccc aagattctca agcatcgtca tcatctaagc tagggttgga tcctcagatt     1560

gggtccctag atgatggtgc aggagacctc tccctatcca aaagctctat ctccatcagt     1620

gaccccctaa acacaccagc attggatttt tctcagttgt ttaatttcat acctttaaat     1680

ggtcctccct ataatcctct atcagtgggg agccttggaa tgagctattc ccaggaagaa     1740

gcacattctt ctgtttccca gctcccccca caaacacagg atcttcagga tcctgcaaac     1800

actatagggc ttgggtctct gcactcactg tcagcagctt tcaccagcag tttaagcaca     1860

agtaccaccc tcccacgttt ccatcaagct tttcagtagg attctgggac atggattcat     1920

tacagaaatg tatgtgtagc tgtgccctag atgaccattt ttattttagt gcctacttta     1980

aaacagtata aaaatttctg cttttgtata atacaaattt tcattaagcc agtataaaat     2040

agaaactagc ttttaaactg agctttggaa ccatttgtgt tcagttaagt ttacctgggt     2100

attttgtcct gattcactgc caattgtcac attttaagac tttttttttt ccatatagga     2160

aagccattat tagtagtaaa cttttacaaa tcccattttc aaattacttt tagatcttaa     2220

aattttcatt tttgtctaat aacagtggct ctaccttttg acatctggct cattaaaaaa     2280

tttagcaata gaatgtaaat tgtataaaaa gtttgtgaat aactcaaggg tttaaatttt     2340

cttactagct tctaaatgga ttaataatca agtgcttcaa atgaattaag agtccagttt     2400

cggaagataa taaatgtttg ttagatacac cataatttca gatcagtata ttctgaagac     2460

tccctgttgt ctggctaaaa tatttgccat ctttattatg agcctttaag gaaaacaaac     2520

cctaaacaca aagcatcagt atttatagca aaaagagact ctgttaggtg acatggcatt     2580

tcgtgtcact taatagttgg ccctaaatta gtacacagga tattttgtcg tgtttcatcc     2640

ttcttaacat gctatctttt catttaataa tagtaatagt gtatggcatt ggggtcttca     2700

gagtcgatat ataggtagat ctctttagtc ttttccacct ttcacatcca aggggtgggt     2760

caagtgcagc cagcaattta ttttcattgt tggcccacgg ttagtccata atctagagcc     2820

attgtggaac tgcagccatg aggtgtgttt atcccacagt ggattgactc agcctctgtg     2880

ggtgacagac ttctaagcag gaagatagac gtgaagcaca tggttacatt tgggaacttg     2940

tgtagggatc atggcccctg tagccagggt taaaaactgg actttttaga agtaaagtaa     3000

aagcatatcg cttatatcat ttcttgctga atttgatatg tttttctttc ccttaagaat     3060

caaaagcaga aaacaaaaac aacagtccta ctccgatgtt atctttctga ttcaatgtga     3120

atccatcttt ccttgcaata ttttggatgg agaatttgaa gttaaatgca ttagaaaact     3180

acctgatgaa ctaccacaaa gttttaagtg actagaaata tatacagtaa aatcccactt     3240

tcatgcatct ctgggaaatg ataggagtat tgcaaataag ttgagtttgt agagggtaac     3300

aaagtaaagt aaaacaaacc tatcttggtt aacatgaaaa taacaattga gaatatatta     3360

tattcactga ataattatag gcttttcctc acattagaca accaacataa tcttcttaaa     3420

ggtctaatta atatattttt ctaagggtca gttgggacat taacctaaga aacatatcta     3480

ttaagcactt gttaacacct tattttagga ccctttccgt tggggatggg ggcaagggtg     3540

ggaggttttt agaagagtat atatctcttt aaaaaaaaac agaaagaaaa atatttctga     3600

gcactcatta gccctatatg gaaacttctt tcctttttgt agggccagtt atcactgcag     3660

attgcaatgt ttaccaagaa tttctaaaaa tgagtgcaga ttactgaata taatacatta     3720

tttaaaatat ttgggagtag tataatttgt ggagaaatgt aaattgtaat aatgtaaatg     3780

ggggcttcaa tatatatata taatacacac acacacacac atgcacacat accgcacttc     3840

atagaatcaa agttgctctc tgaaggagct ttggctcctg atattttatc atgctcctat     3900

atttttttaa tccttggagc agtagttttt atacttatgt atttaaattt tattatgaaa     3960

aattacattt attaaaaaag tgtgttccaa aggcattaaa attatatatg ttaataagga     4020

agtacatttt taaatttttc aaactgctcc tagcttttga ttaggagaat attttttctg     4080

aaagtaggct tttcgctctg cttcattact gcttccttta gtttctatga aacagattgc     4140

ttacctaaat ctttagttga atgattagtg ttcaatattg ctttaatcac catataaaag     4200

gaaaaaaatt ggtgacagag cacaaataga aaacctattt ttaaatagaa atcacaaata     4260

gcaagtgtgg aagcactact ttattctgtt taaaatgtac ttaagaagtc atcaaattag     4320

tgaactgaga cattggcctt agtaggctgt attcactgct aatttaaaaa agggagtacc     4380

aggatttatt aagtaaagca ttttggaaat ggggaatagc gccatatatg tatgtatgtg     4440

tatgtgtgtg tgtgtgtgtg tatatataca cacacacaca catacttaaa tcttgccctg     4500

catgaaattc aaatacatgg aggcacatct tcagggcacc agtgttaaaa ttttggagtc     4560

ttaattttca tgtgtacacc tctttgcctg ttcccacccc cagacttgaa ataacacttc     4620

agagtaagag ggaattcagc taatttgttt ttaaaattga ctgtagtggt cactaaaccc     4680

tttttgagag aatttctatt aaagatgagg cagactcgct tatttgaatt gcacaatgtt     4740

ctaacaagga tgtaacacag aattggcttt tttttcccta gaaaaagatt gtttgtttct     4800

atgtcaacta gatatgatta aaaataagta ttgccaatgc tgttttcatt ctctagtggc     4860

cagaatcatt atccttgaaa tttctggtag tgccttagct tggttaaaaa aaaaaaaaaa     4920

aaaaaaaaaa agggattaac attaaataaa agtagtttag aatttgggcc tcagacaaga     4980

tattgaacct cattcagttt cacttccaca tgtatgtaca agttaggtca ccaaacacgg     5040

aagtgtgagt gtggaaggat cttggcactg taagcaatgc tatccattga tgtatacaag     5100

tacctttata gttatcgatc actgttaaaa ctttcatttt aaaatcctat taccaagttc     5160

agttttttaa aacttcaatt gtcctggctg attatgcatc actctgtgtg caactttttt     5220

atttcattta gtgtttcttt caagctgtgt atttttgcct atttgttgct tgtgctttat     5280

ttttcttagt catttgtgga atatagtgat atattgtgtt aatttggaca gtagcggttt     5340

ttaaaaacca tatactgact gaaacatgag ccagagccga ttgctttatt aagctaataa     5400

tgaatgttaa agagtacata ttttcaggat cgttcatcta gtgagcaata cacatattat     5460

aggccaatat ttttttaaaa aatagagctt ggtcaacctc tatactacac atattacaag     5520

atatagcact ttcaaaatga atctaaacct ttacagaaac tttcttatag gttatgcctt     5580

ttattttaag acttattata attcaagtgc cattagatga tatatatgta ggcctttgat     5640

atataatgct ttgtgtacaa aaatggtaga tggtatttta aacaggtaca tttttacagt     5700

gttttcttat caatttgcta tattgcacag aatcagtgtg tgtcttttca taaggtttta     5760

caatggttta tttttttaca aggtttacgt gtctcaaagc acactgtctt cccagtacgt     5820

aagttaaaaa ataccagttc acccaagttg cttctagcct actgagatcc atgtgacatt     5880

ggaggagatc ttttaaatgt ttagtattcg tcattagcaa tggctggctg ttagttctgg     5940

taaatgtgtg cctaagttga atttgtcttg tttttctcac actgtgtcag cagccatgtc     6000

tacaacacag ataagtctgt tgtgatcaca tagatctaca taagttgtgc agttttgtgc     6060

taaaaaccca tagggagctc ctttgggatc atagaaaaga agatcatgca accagcattg     6120

gtgaaggcac actcagattg cacttagggc ctttctatga tgttgtcaac cctctgagga     6180

tggaaggcag tgtcttttga tgttatctag cctagaaatg acacagaact attgctaatg     6240

tataaaacac ttcattatat aagcttcagt ggtacagatg aaccagaatg aatgtttatc     6300

ttctcagaaa cactccttca atattatatt ggatcatgct gctaatgtaa cttgggctac     6360

aactcttcat ggtgctacaa acttctctgt ctcattcagt cgtatttttt tatccataga     6420

aaaaggacta cattaggtgt aaaagtgtac aatatatttt tatactgtga cttaatttgt     6480

cattaacaaa cttttacacc accacaatgt attcatgtgc acttgcaaaa ggagatctcg     6540

gacatgcaaa tgttaccaga acaaacccag cttttgtcca caaggtgact gtaactcaga     6600

atggaaagtg ggctttataa tagggtgtgg agtgaagaac atgctgtatg ttactaacag     6660

ccctttgaat ttaacaaaaa ctgggaatcc attaggaaac ggattgcatc atacctgaac     6720

ataagctgga ctgctgaaat tgtattttta gctaatgaaa aagtgtttgg actagtactc     6780

taaaaatgtt ctaatgataa agttttgagt caaaatagaa aagaaaaaaa tctgcattcc     6840

aggccgaatt ttgtatattt ttattgcatt taaaattgct attctgtaat attgggaaat     6900

caagtggctt atcatgtata tcgtgtactt aaaatgtatt cacaaactac tgttgtattt     6960

gtataaaata tagacaaaga tcatattttt tgtgtgtgta taagctctgt aaaatagcaa     7020

tcacattatg aagctgcagt gatactacat tttaaacatt cacatccaaa gaagcagact     7080

atttattgtc catataccag atttaaaata ttaatttgct gctaattaaa taatagtact     7140

gcagcttctt gtggcctaca gtgttatgtt tgctgtaaga ataagatatg tgaattccac     7200

aaaatatatg aataaaatta tagaatggct tta                                  7233


<210>  1554
<211>  1878
<212>  DNA
<213>  homo sapiens

<400>  1554
gattgtggga aggcagctga actcggcgcc tggaaagatg gaggcagcgg agacagaggc       60

ggaagctgca gccctagagg tcctggctga ggtggcaggc atcttggaac ctgtaggcct      120

gcaggaggag gcagaactgc cagccaagat cctggttgag tttgtggtgg actctcagaa      180

gaaagacaag ctgctctgca gccagcttca ggtagcggat ttcctgcaga acatcctggc      240

tcaggaggac actgctaagg gtctcgaccc cttggcttct gaagacacga gccgacagaa      300

ggcaattgca gctaaggaac aatggaaaga gctgaaggcc acctacaggg agcacgtaga      360

ggccatcaaa attggcctca ccaaggccct gactcagatg gaggaagccc agaggaaacg      420

gacacaactc cgggaagcct ttgagcagct ccaggccaag aaacaaatgg ccatggagaa      480

acgcagagca gtccagaacc agtggcagct acaacaggag aagcatctgc agcatctggc      540

ggaggtttct gcagaggtga gggagcgtaa gacagggact cagcaggagc ttgacagggt      600

gtttcagaaa cttggaaacc tgaagcagca ggcagaacag gagcgggaca agctgcagag      660

gtatcagacc ttcctccagc ttctgtatac cctgcagggt aagctgttgt tccctgaggc      720

tgaggctgag gcagagaatc ttccagatga taaaccccag cagccgactc gaccccagga      780

gcagagtaca ggagacacca tggggagaga ccctggtgtg tccttcaagg ctgttggtct      840

acaacctgct ggagatgtaa atttgccatg acttcctgga ggacagcagc atggagaaag      900

atcctagaaa aggtcagacc caactcaggc cttggtgtcc ctggactgca agtgtggaag      960

gagggaaagc ctggtttacc tctctctgca tctgagctct gctacccatg gagcagatgg     1020

atggtgggaa caggaaagag cttatgttac acctcattcc catgcttagc ccacccagag     1080

ctaacccctg tcttcttccc caggcctctg acttccctca cctcccaacc atcattacag     1140

gaaagactgt gaactcctga gttcagcttg atttctgact acatcccagc aagctctggc     1200

atctgtggat taaaatccct ggatctctct cagttgtgta tttgttcatc ttcatatgct     1260

ggcaggaaca actattaata cagatactca gaagccaata acatgacagg agctgggact     1320

ggtttgaaca cagggtgtgc agatggggag ggggtactgg ccttgggcct cctatgatgc     1380

agacatggtg aatttaattc aaggaggagg agaatgtttt aggcaggtgg ttatatgtgg     1440

gaagataatt ttattcatgg atccaaatgt ttgttgagtc ctttctttgt gctaaggttc     1500

ttgcggtgaa ccagaattat aacagtgagc tcatctgact gttttaggat gtacagccta     1560

gtgttaacat tcttggtatc tttttgtgcc ttatctaaaa catttctcga tcactggttt     1620

cagatgttca tttattatat tcttttcaaa gattcagaga ttggcttttg tcatccacta     1680

ttgtatgttt tgtttcattg acctctagtg ataccttgat ctttcccact ttctgttttc     1740

ggattggaga agatgtacct tttttgtcaa ctcttacttt tatcagatga tcaactcacg     1800

tatttggatc tttatttgtt ttctcaaata aatatttaag gttatacatt taaaaaaaaa     1860

aaaaaaaaaa aaaaaaaa                                                   1878


<210>  1555
<211>  4304
<212>  DNA
<213>  homo sapiens

<400>  1555
gtcgcgggca gctggcgccg cgcggtcctg ctctgccggt cgcacggacg caccggcggg       60

ccgccggccg gagggacggg gcgggagctg ggcccgcgga cagcgagccg gagcgggagc      120

cgcgcgtagc gagccgggct ccggcgctcg ccagtctccc gagcggcgcc cgcctcccgc      180

cggtgcccgc gccgggccgt ggggggcagc atgcccgcgc gcgctgcctg aggacgccgc      240

ggcccccgcc cccgccatgg gcgcccctgc ctgcgccctc gcgctctgcg tggccgtggc      300

catcgtggcc ggcgcctcct cggagtcctt ggggacggag cagcgcgtcg tggggcgagc      360

ggcagaagtc ccgggcccag agcccggcca gcaggagcag ttggtcttcg gcagcgggga      420

tgctgtggag ctgagctgtc ccccgcccgg gggtggtccc atggggccca ctgtctgggt      480

caaggatggc acagggctgg tgccctcgga gcgtgtcctg gtggggcccc agcggctgca      540

ggtgctgaat gcctcccacg aggactccgg ggcctacagc tgccggcagc ggctcacgca      600

gcgcgtactg tgccacttca gtgtgcgggt gacagacgct ccatcctcgg gagatgacga      660

agacggggag gacgaggctg aggacacagg tgtggacaca ggggcccctt actggacacg      720

gcccgagcgg atggacaaga agctgctggc cgtgccggcc gccaacaccg tccgcttccg      780

ctgcccagcc gctggcaacc ccactccctc catctcctgg ctgaagaacg gcagggagtt      840

ccgcggcgag caccgcattg gaggcatcaa gctgcggcat cagcagtgga gcctggtcat      900

ggaaagcgtg gtgccctcgg accgcggcaa ctacacctgc gtcgtggaga acaagtttgg      960

cagcatccgg cagacgtaca cgctggacgt gctggagcgc tccccgcacc ggcccatcct     1020

gcaggcgggg ctgccggcca accagacggc ggtgctgggc agcgacgtgg agttccactg     1080

caaggtgtac agtgacgcac agccccacat ccagtggctc aagcacgtgg aggtgaatgg     1140

cagcaaggtg ggcccggacg gcacacccta cgttaccgtg ctcaagacgg cgggcgctaa     1200

caccaccgac aaggagctag aggttctctc cttgcacaac gtcacctttg aggacgccgg     1260

ggagtacacc tgcctggcgg gcaattctat tgggttttct catcactctg cgtggctggt     1320

ggtgctgcca gccgaggagg agctggtgga ggctgacgag gcgggcagtg tgtatgcagg     1380

catcctcagc tacggggtgg gcttcttcct gttcatcctg gtggtggcgg ctgtgacgct     1440

ctgccgcctg cgcagccccc ccaagaaagg cctgggctcc cccaccgtgc acaagatctc     1500

ccgcttcccg ctcaagcgac aggtgtccct ggagtccaac gcgtccatga gctccaacac     1560

accactggtg cgcatcgcaa ggctgtcctc aggggagggc cccacgctgg ccaatgtctc     1620

cgagctcgag ctgcctgccg accccaaatg ggagctgtct cgggcccggc tgaccctggg     1680

caagcccctt ggggagggct gcttcggcca ggtggtcatg gcggaggcca tcggcattga     1740

caaggaccgg gccgccaagc ctgtcaccgt agccgtgaag atgctgaaag acgatgccac     1800

tgacaaggac ctgtcggacc tggtgtctga gatggagatg atgaagatga tcgggaaaca     1860

caaaaacatc atcaacctgc tgggcgcctg cacgcagggc gggcccctgt acgtgctggt     1920

ggagtacgcg gccaagggta acctgcggga gtttctgcgg gcgcggcggc ccccgggcct     1980

ggactactcc ttcgacacct gcaagccgcc cgaggagcag ctcaccttca aggacctggt     2040

gtcctgtgcc taccaggtgg cccggggcat ggagtacttg gcctcccaga agtgcatcca     2100

cagggacctg gctgcccgca atgtgctggt gaccgaggac aacgtgatga agatcgcaga     2160

cttcgggctg gcccgggacg tgcacaacct cgactactac aagaagacaa ccaacggccg     2220

gctgcccgtg aagtggatgg cgcctgaggc cttgtttgac cgagtctaca ctcaccagag     2280

tgacgtctgg tcctttgggg tcctgctctg ggagatcttc acgctggggg gctccccgta     2340

ccccggcatc cctgtggagg agctcttcaa gctgctgaag gagggccacc gcatggacaa     2400

gcccgccaac tgcacacacg acctgtacat gatcatgcgg gagtgctggc atgccgcgcc     2460

ctcccagagg cccaccttca agcagctggt ggaggacctg gaccgtgtcc ttaccgtgac     2520

gtccaccgac gagtacctgg acctgtcggc gcctttcgag cagtactccc cgggtggcca     2580

ggacaccccc agctccagct cctcagggga cgactccgtg tttgcccacg acctgctgcc     2640

cccggcccca cccagcagtg ggggctcgcg gacgtgaagg gccactggtc cccaacaatg     2700

tgaggggtcc ctagcagccc accctgctgc tggtgcacag ccactccccg gcatgagact     2760

cagtgcagat ggagagacag ctacacagag ctttggtctg tgtgtgtgtg tgtgcgtgtg     2820

tgtgtgtgtg tgtgcacatc cgcgtgtgcc tgtgtgcgtg cgcatcttgc ctccaggtgc     2880

agaggtaccc tgggtgtccc cgctgctgtg caacggtctc ctgactggtg ctgcagcacc     2940

gaggggcctt tgttctgggg ggacccagtg cagaatgtaa gtgggcccac ccggtgggac     3000

ccccgtgggg cagggagctg ggcccgacat ggctccggcc tctgcctttg caccacggga     3060

catcacaggg tgggcctcgg cccctcccac acccaaagct gagcctgcag ggaagcccca     3120

catgtccagc accttgtgcc tggggtgtta gtggcaccgc ctccccacct ccaggctttc     3180

ccacttccca ccctgcccct cagagactga aattacgggt acctgaagat gggagccttt     3240

accttttatg caaaaggttt attccggaaa ctagtgtaca tttctataaa tagatgctgt     3300

gtatatggta tatatacata tatatatata acatatatgg aagaggaaaa ggctggtaca     3360

acggaggcct gcgaccctgg gggcacagga ggcaggcatg gccctgggcg gggcgtgggg     3420

gggcgtggag ggaggcccca gggggtctca cccatgcaag cagaggacca gggccttttc     3480

tggcaccgca gttttgtttt aaaactggac ctgtatattt gtaaagctat ttatgggccc     3540

ctggcactct tgttcccaca ccccaacact tccagcattt agctggccac atggcggaga     3600

gttttaattt ttaacttatt gacaaccgag aaggtttatc ccgccgatag agggacggcc     3660

aagaatgtac gtccagcctg ccccggagct ggaggatccc ctccaagcct aaaaggttgt     3720

taatagttgg aggtgattcc agtgaagata ttttatttcc tttgtccttt ttcaggagaa     3780

ttagatttct ataggatttt tctttaggag atttattttt tggacttcaa agcaagctgg     3840

tattttcata caaattcttc taattgctgt gtgtcccagg cagggagacg gtttccaggg     3900

aggggccggc cctgtgtgca ggttccgatg ttattagatg ttacaagttt atatatatct     3960

atatatataa tttattgagt ttttacaaga tgtatttgtt gtagacttaa cacttcttac     4020

gcaatgcttc tagagtttta tagcctggac tgctaccttt caaagcttgg agggaagccg     4080

tgaattcagt tggttcgttc tgtactgtta ctgggccctg agtctgggca gctgtccctt     4140

gcttgcctgc agggccatgg ctcagggtgg tctcttcttg gggcccagtg catggtggcc     4200

agaggtgtca cccaaaccgg caggtgcgat tttgttaacc cagcgacgaa ctttccgaaa     4260

aataaagaca cctggttgct aacctggaaa aaaaaaaaaa aaaa                      4304


<210>  1556
<211>  9580
<212>  DNA
<213>  homo sapiens

<400>  1556
cagaacactg cgtgtcctgt gcgcgagtac gggtccggcc gcgggtccca ccgcaagcgg       60

gcgtgtgcag ctgcggctgc ctggcgggcg agcttaggag ggagctggag ctgcggagcg      120

gcgggaacag gagcaggccg agggtcctct ggccagaaga aatctggcct cggaacacgc      180

cattctccgc gccgcttcca ataaccacta acatccctaa cgagcatccg agccgagggc      240

tctgctcgga aatcgtcctg gcccaactcg gcccttcgag ctctcgaaga ttaccgcatc      300

tatttttttt tctttttttt cttttcctag cgcagataaa gtgagcccgg aaagggaagg      360

agggggcggg gacaccattg ccctgaaaga ataaataagt aaataaacaa actggctcct      420

cgccgcagct ggacgcggtc ggttgagtcc aggttgggtc ggacctgaac ccctaaaagc      480

ggaaccgcct cccgccctcg ccatcccgga gctgagtcgc cggcggcggt ggctgctgcc      540

agacccggag tttcctcttt cactggatgg agctgaactt tgggcggcca gagcagcaca      600

gctgtccggg gatcgctgca cgctgagctc cctcggcaag acccagcggc ggctcgggat      660

ttttttgggg gggcggggac cagccccgcg ccggcaccat gttcctggcg accctgtact      720

tcgcgctgcc gctcttggac ttgctcctgt cggccgaagt gagcggcgga gaccgcctgg      780

attgcgtgaa agccagtgat cagtgcctga aggagcagag ctgcagcacc aagtaccgca      840

cgctaaggca gtgcgtggcg ggcaaggaga ccaacttcag cctggcatcc ggcctggagg      900

ccaaggatga gtgccgcagc gccatggagg ccctgaagca gaagtcgctc tacaactgcc      960

gctgcaagcg gggtatgaag aaggagaaga actgcctgcg catttactgg agcatgtacc     1020

agagcctgca gggaaatgat ctgctggagg attccccata tgaaccagtt aacagcagat     1080

tgtcagatat attccgggtg gtcccattca tatcagatgt ttttcagcaa gtggagcaca     1140

ttcccaaagg gaacaactgc ctggatgcag cgaaggcctg caacctcgac gacatttgca     1200

agaagtacag gtcggcgtac atcaccccgt gcaccaccag cgtgtccaac gatgtctgca     1260

accgccgcaa gtgccacaag gccctccggc agttctttga caaggtcccg gccaagcaca     1320

gctacggaat gctcttctgc tcctgccggg acatcgcctg cacagagcgg aggcgacaga     1380

ccatcgtgcc tgtgtgctcc tatgaagaga gggagaagcc caactgtttg aatttgcagg     1440

actcctgcaa gacgaattac atctgcagat ctcgccttgc ggattttttt accaactgcc     1500

agccagagtc aaggtctgtc agcagctgtc taaaggaaaa ctacgctgac tgcctcctcg     1560

cctactcggg gcttattggc acagtcatga cccccaacta catagactcc agtagcctca     1620

gtgtggcccc atggtgtgac tgcagcaaca gtgggaacga cctagaagag tgcttgaaat     1680

ttttgaattt cttcaaggac aatacatgtc ttaaaaatgc aattcaagcc tttggcaatg     1740

gctccgatgt gaccgtgtgg cagccagcct tcccagtaca gaccaccact gccactacca     1800

ccactgccct ccgggttaag aacaagcccc tggggccagc agggtctgag aatgaaattc     1860

ccactcatgt tttgccaccg tgtgcaaatt tacaggcaca gaagctgaaa tccaatgtgt     1920

cgggcaatac acacctctgt atttccaatg gtaattatga aaaagaaggt ctcggtgctt     1980

ccagccacat aaccacaaaa tcaatggctg ctcctccaag ctgtggtctg agcccactgc     2040

tggtcctggt ggtaaccgct ctgtccaccc tattatcttt aacagaaaca tcatagctgc     2100

attaaaaaaa tacaatatgg acatgtaaaa agacaaaaac caagttatct gtttcctgtt     2160

ctcttgtata gctgaaattc cagtttagga gctcagttga gaaacagttc cattcaactg     2220

gaacattttt tttttttcct tttaagaaag cttcttgtga tcctttgggg cttctgtgaa     2280

aaacctgatg cagtgctcca tccaaactca gaaggctttg ggatatgctg tattttaaag     2340

ggacagtttg taacttgggc tgtaaagcaa actggggctg tgttttcgat gatgatgatg     2400

atcatgatga tgatcatcat gatcatgatg atgatcatca tgatcatgat gatgatttta     2460

acagttttac ttctggcctt tcctagctag agaaggagtt aatatttcta aggtaactcc     2520

catatctcct ttaatgacat tgatttctaa tgatataaat ttcagcctac attgatgcca     2580

agcttttttg ccacaaagaa gattcttacc aagagtgggc tttgtggaaa cagctggtac     2640

tgatgttcac ctttatatat gtactagcat tttccacgct gatgtttatg tactgtaaac     2700

agttctgcac tcttgtacaa aagaaaaaac acctgtcaca tccaaatata gtatctgtct     2760

tttcgtcaaa atagagagtg gggaatgagt gtgccgattc aatacctcaa tccctgaacg     2820

acactctcct aatcctaagc cttacctgag tgagaagccc tttacctaac aaaagtccaa     2880

tatagctgaa atgtcgctct aatactcttt acacatatga ggttatatgt agaaaaaaat     2940

tttactacta aatgatttca actattggct ttctatattt tgaaagtaat gatattgtct     3000

cattttttta ctgatggttt aatacaaaat acacagagct tctttcccct cataagtagt     3060

gttcgctctg atatgaactt cacaaataca gctcatcaaa agcagactct gagaagcctc     3120

gtgctgtagc agaaagttct gcatcatgtg actgtggaca ggcaggagga aacagaacag     3180

acaagcattg tcttttgtca ttgctcgaag tgcaagcgtg catacctgtg gagggaactg     3240

gtggctgctt gtaaatgttc tgcagcatct cttgacacac ttgtcatgac acaatccagt     3300

accttggttt tcaggttatc tgacaaaggc agctttgatt gggacatgga ggcatgggca     3360

ggttctcctt tctttggaaa cacatccatg ctgggatgca cagttctttt cctaaggatt     3420

gtgtttactc ctgactgcaa cgtcttggcc actgtttgga gcagtttggt ctgaaggtca     3480

ttaaggatct gcttgcatct tgtttcatgt cctccgtgac agactgcaga ccatgttaga     3540

agagaaggaa ggtttgtgga tcaagagggt tgacattagg tttggtgaga tgagttgctt     3600

ggcacagatc agcagaacag gaccctggtg ataaggcatc tggctttgct aaccacttat     3660

catcttccat tattctcttt cttaactaag tagacccgaa agtgcacttt tgaagtctgg     3720

tttagatggc gagattccga atctacaatg atcgagtact ggtggccact tttctccaac     3780

attaagtaaa gaggaggaga ttccaccttc agaaagtgct gggaagcatt ggctttcttc     3840

ccacattggt agaagagatg gaggaggaaa ccagggtgca catttctaca gatccccttt     3900

gcctgctggt gtttgccttg taagataagt cactgggggg aaggggaaat ctatgaaatc     3960

caagataaag gcatagtctt tcagctctat tggtgttaaa agtatatttg tgtccaaatg     4020

ttaatcaaca caaatgtaca gtactcagta ctgacttttt tcacttcaaa atgttttcaa     4080

gggaaattca gcagacaccc aactgtattt aattagtgaa aagatctata aagactctta     4140

ctttgaataa acacattaag taagtgtgtc aaaatatttg gaatgccagt tatctatgag     4200

cgcatatctc ttacagagtg tattttgttt tcattaaggt atctctgtgt atctacactg     4260

gactaatttc atagggatct gattctatgt gatccactgt agaaagctac tgattacttc     4320

tgcagtaaca gcagctctaa ttagcatcag atgaccaaag cggaaatggg agtttcagcg     4380

ctaacaaggg cagccttcat tgaagaatgc atgggtaggc aatatataaa ttacattttg     4440

aaaagcctca tctgtcacca acaaatatct catttttctt cagtgataaa agcatattca     4500

agttaccagc tcctcaattt gaaaatcagt tgctgattaa ataaataggg ggaagcatct     4560

tgttcaggga caacacgtta gagagattct tatcaaagca agccaagcaa ggtttccgcc     4620

attcagtgtg atcttagttt gacacggtga ccctaaaaca ccatcatttg ccccagaact     4680

ggagcacaat aagttaaatc atttacctgt ctcacttctt cttggcgtgc ttaaaagcaa     4740

aaatgattcg ctacttcctg tccttcagtc cgggcatttg gggtgccact gaagacaggg     4800

gttatctgct gaggtttggg tgtcttgcag gaagtatctc attgcagttg attttgatga     4860

aaccaaacag taactagggt ccatgcagac cgtgactccc tgattacatc tagccatgcc     4920

ctacttattt cagagagaaa gagaggggga ataaaggcag tattgccaca ctgattagaa     4980

gcacattcat tccactttga tgttgaatat ttttgaccga tacatgcttg agtatctttt     5040

taatagagca catgaaggaa gaagcacaca atatagagaa ggaattgaga atgccaatta     5100

catatttatt tttccatacc tgattttttt caagtctgta ataaaaaaag tataagttga     5160

gattaacata ggttattttt catgaagtat agcaaacgat ctagaatgtg ataggagtgt     5220

ggtttccatt tctttttttt tttttttaac agacttttgt gctgtagtaa gaatgtctta     5280

gaagttgtgt cttcgagttc ctcaaacacc ggacagggct cccccagagc tgcctcagcc     5340

tttgatttgg tccatattca gacacttcct gtcttgcata cactctgagg atgggccgct     5400

tctagctgcc gcccgtctcc ctcttgcctt cttgtctcta aatcagacac tcccaagcac     5460

tccatctgct atactaggag agtgggagag ccaaagcatt ttggagtcca tgtaaagtgc     5520

ctgggaaaag agatgtaaga gcagtgggag tttatataat tagcgaattc ttttctcaga     5580

attcagcgga aatgtatttc tgttgttatt atttacaaaa ttgtggcctc agaggagctg     5640

tcttttggaa aataagtttt cattcatgca gttagttaga catgcacgat gtacttgaat     5700

caataaactg tggaccagaa aagggctgct taaatgaatt cacgtgttct aattctcttt     5760

cgaggctgtt gatgacctcc tggattcata cccccatgat ctgtcttgct cttgcctctg     5820

ttctttgata aagcacatca gactatgtga cacccatctt ttcaagaacg acctaaaagc     5880

aatgacaaca ggcaggagag aattaccact ggcctgggca cagtgacagc agaaggccca     5940

cctgagcttg gagagttggc gagataaggc aaaatcaagg tgcaacagtg ggccatgttc     6000

caagggtgaa tggatctgag agtccgctga tgttccttac tgatcagaac agggaccttc     6060

taacgaaaca gccagagttc cttgaatcag gcagaagttc tttagagaca ggaagccaga     6120

gctattgata atatccgaac gacagaggaa ggaatttctt attagaaatt ctaaaataaa     6180

acaagtgggg atttggttgg atacccttag aagctacatt tttctctcat ccctaagata     6240

gatatctcaa gtgtatatct gacacctctt ggctttgaca cggctctgct tctcaagtga     6300

ccatttgttt taagtctgtt gtctagaatt ctttgtgggg gctggacctc tgaaaaagat     6360

tctcactgca gaggctttaa atctgtgttt ttttccactc cctccgtcct gggatgtatt     6420

cggtaggaca tttcatttat atcaggatat tggctgattc agctctcttt catcgttatt     6480

attcaggcct ccctccacca ccttgttctt tattgcctaa gtattgccct ccccaattct     6540

tcatcgtaat agctctaaat ttagtttgac ccaaattaat ttttgttcca acagatatat     6600

tttaagacag agaagcctct ctcaggagcc agatgatctg aagatgatgc taatccccaa     6660

atacgaagtt cctccagcta actctcctct gagctccctc ttcttagctt tgggattggg     6720

gatggtctca tccttgccag gaatcccttt gttgctccca gtgtctctga tgagcttctc     6780

ctccctccca gagacaatgc aggggtggtt ttcagcagaa tgtgccacct gcacttctga     6840

ttgttctgag acccagccca gaggggtgga gaaggcgcac aaaccctatt ccaataaact     6900

gcctgcagag aaccacagcc tgctaatagt cgttgaggtc tcagccccct aaggtctcca     6960

agctcatttg accagcgcag ctgcgacttc ggctgtctgc ctctggcagg tgccaatatc     7020

agcatcttgt cccactgcca tggggagtta atttttgctc cagggcagct gccaagccca     7080

gcaccggcat caatagaagg ttttctctga ttttcttctc ttcctctcag gctaggcttt     7140

cttaccaatc cccaattttc ttctgtaggg cgccaggaga ctggccagag atctttagac     7200

tcttacttag tttgaacatc tcttgctgct cacacccagg cttcttcagc agaaagcatg     7260

acccatagta ggtactcaga aactggttga atgaaaagcc ttgacattta agggctttat     7320

tctgtcatac ggtagcaaga actggcctat tggcatcgta ttcctggcat tgagctgtat     7380

tgaccctgaa tgtgtcctcc tgaggttttt gagggtgacc taggagaaag ggtctgaaaa     7440

agcactggga tccaagtgac tttaaatctg cccgtggcat ttcctgctga gaggcgagaa     7500

actagcatct ctcccaacag gctcacatcc gccaggaagg acagagccca aaacgggggt     7560

agactttgtg ggaaattcgc cagttagtcc gctgagattt taatctgcct caagcacagg     7620

atgctgacaa gaaaggtaga ccactccccc gatcccagac aaaccccagg ggtgacaact     7680

tctccatcag tatcctgaga agcaacatca aatgcttacc aagtcagcac gtttactgag     7740

tgagtactct gacggaataa accagcattt ggagctgaac ttgagaacac agggccctct     7800

gacagcagct tagggaaaca cccatccctt ccagattggc agaatccttc catttcatgt     7860

ccttcggaga cgctgtattc tctttacaaa tcattcatga aactgagact cagtctccca     7920

ggggtaagtc ctgggccacg tgcaaacaat ggcaaatcca gctcttccat gatagagaag     7980

gcaaacacac ccaccttcat cctgagccta aaaggccacc tctgagcact tgggcagcca     8040

ctcctctggg cctcagaggg ccatgagctt ggccaggtag gcacagcggc ggggaagtca     8100

cagctgtcag gtaccggcca tggtgcaggt gggaatagga gatgccagag ctgctttagc     8160

tgaggaaagc aaacagtcag cagtgctcaa aggagcaaaa cttcgaatgt gcacattgac     8220

ccctgacacc tgcaagcata acacagatcc taagactaga gtgaagtagg aagaagaatt     8280

agaaaatcca gtggatgtcc tgagtatagg gaaccagggc cgttgaaaat cagtaaaggt     8340

tgattacctg gggcgagacc gggtgactgt ggcagtgcag gtgaaggtac cctggacctt     8400

ctcagttcgc tggcacataa ggctccgcca ataaagcgtg gttctctctg tcacacacac     8460

acacacacac acacacacac acacacacac acacacacac acaatgattg gagggctata     8520

tgatccagca ttagcttcct ggtgtgccaa gcatgcttga tcgggaattt ttttttatta     8580

ttattatttt ttagctgtag ctgaaggcat ttctcggatg tggagaggag aatggaaatc     8640

gcagaaccaa atcagtttgc cctgccatat ttggctgtgg tctgtcattg ggcatttctg     8700

atgtgctttt ctggattcag gaagagctga ttgtcctccg agggttgaaa aaaaaaaaac     8760

agtttcagaa acctgaatcc agggccttat agttctcctc attatctatc ttcttctccc     8820

ttccctcgcc caagggagtg ggggaaacac ttttcactgc agagtttgct ttaaagtttt     8880

cccatcttgc gtgcattatc ccttgatatt aaaattattt tctcagttta atccaactcc     8940

tgctgagaag ctgtgtgaga tttaggctgt ggggtttttt tcttgtactc ttttggatgg     9000

tgttgcattt ttcactctta acccgagggt gtgtttcagc ttatgttcgt tctgtttcat     9060

gcaggtttat agcacggtag agtagaaggc ggcttctgat ttttagggta tttttagaat     9120

tcattcctga gtgaggggtt cagacaccca gtctcctcgg aacaggggtg aggggtcgac     9180

tgagctttgt tgagaagcct ccagttaggc ttcgggcggg tctccatgtt atattgtgtg     9240

tttactgagc ttcccactgg tagaagatga cacatttgtc catcgtcctg tgtatctgct     9300

ttccagagga caccggagca ttctcctggg gtcactccca catggctgcc tcacatagct     9360

gttttgcaac agcctttatt gccaacaccc ttggaagaac atctcctgta gaagtacaag     9420

ttttgcaata tggactttgg aagtggtttt gtgatgttcg aattttctgt tagcctattg     9480

ctcaagcact acagaatgta catagtccct ttggccatcc tctcacccca gaatatccta     9540

ataaacattg ttttcttttt taaaaaaaaa aaaaaaaaaa                           9580


<210>  1557
<211>  10995
<212>  DNA
<213>  homo sapiens

<400>  1557
gagcatcttt tggggggagg gaattcagcg gatcagtctt aagaggagct tttttttgga       60

gcgagaaatc atataaaata aaatgaaata aaacaaggag gaaggcaacc agctgttagg      120

ggaaaaataa ggcagataaa ggagcgggga gagaaattaa ttgccaacca ggaggagttg      180

ggctgtattt ttcaaaggtg gggagagtgg agcacacacc ttgaggagga aagcgagaaa      240

gaaaagaaaa aagcaagtgg aaaggggggc tcgcccaaga agggtgaaga agcgaagaaa      300

gtcgaggcgc cgaggctccc aaagctggca gctccgggtg gcggtgcagg ggcgaagggg      360

gggcgggggg aaccgtcgga catgcggctc tggagttggg tgctgcacct ggggctgctg      420

agcgccgcgc tgggctgcgg gctggccgag cgtccccgcc gggcccggag agacccgcgg      480

gccggccgac ccccgcgccc cgccgccggc ccggccacct gcgccacccg ggcggcccgc      540

ggccgccgcg cctcgccgcc gccgccgccg ccgccgggcg gtgcctggga agccgtgcgc      600

gtcccccggc ggcggcagca gcgggaggcg aggggcgcca ccgaggagcc gagcccgccg      660

agccgggcgc tctatttcag cgggcgaggc gagcagctgc gcctccgggc cgacctcgag      720

ctgccccggg acgcgttcac gctgcaagtg tggctgcgag cggagggggg ccagaggtct      780

ccggcagtga tcacagggct gtatgacaaa tgttcttata tctcacgtga ccgaggatgg      840

gtcgtgggca ttcacaccat cagtgaccaa gacaacaaag acccacgcta ctttttctcc      900

ttgaagacag accgagcccg gcaagtgacc accatcaatg cccaccgcag ctacctccca      960

ggccagtggg tatacctagc tgccacctat gatgggcagt tcatgaagct ctatgtgaat     1020

ggtgcccagg tggccacctc tggggaacaa gtgggtggca tattcagccc actgacccag     1080

aagtgcaaag tgctcatgtt agggggcagt gccctgaatc acaactaccg gggctacatc     1140

gagcacttca gtctgtggaa ggtggccagg actcagcggg agatactgtc tgacatggaa     1200

acccatggcg cccacactgc tctacctcag ctcctcctcc aggagaactg ggacaatgtg     1260

aagcatgcct ggtcccccat gaaggatggc agcagcccca aagtggaatt cagcaatgcc     1320

cacggctttc tgctggacac gagtctggag cctcctctgt gcggacagac attgtgtgac     1380

aacacagagg tcattgccag ctacaatcag ctctcaagtt tccgccagcc caaggtggtg     1440

cgctaccgcg tggtcaacct ctatgaagat gatcataaga acccgacggt gacgcgcgag     1500

caggtggact tccagcacca tcagctggct gaggccttca agcaatacaa catctcctgg     1560

gagctggacg tgctggaggt gagcaactcc tcccttcgcc gccgcctcat cctggccaac     1620

tgtgacatca gcaagattgg ggatgagaac tgtgaccccg agtgcaacca cacgctgacg     1680

ggccacgacg gcggggattg ccgccacctg cgccaccctg ccttcgtgaa gaagcagcac     1740

aacggggtgt gtgacatgga ctgcaactat gaacggttca actttgatgg tggagagtgc     1800

tgtgaccctg aaatcaccaa tgtcactcag acttgctttg accccgactc tccacacaga     1860

gcctacttgg atgttaatga gctgaagaac attcttaaat tggatggatc aacacatctc     1920

aatattttct ttgcaaaatc ctcagaggag gagttggcag gagtagcaac ttggccatgg     1980

gacaaggagg ccctgatgca cttaggtggc attgtcttga acccatcttt ctatggcatg     2040

cctgggcaca cccacaccat gatccatgag attggtcaca gcctgggcct ctatcacgtc     2100

ttccgaggca tctcagaaat ccagtcctgc agtgacccct gcatggagac agagccctcc     2160

ttcgagactg gagacctctg caatgatacc aacccagccc ctaaacacaa gtcctgtggt     2220

gacccagggc caggaaatga cacctgtggc tttcatagct tcttcaacac tccttacaac     2280

aacttcatga gctatgcaga tgacgactgt acggactcct tcacgcccaa tcaagtcgcc     2340

agaatgcact gttacctgga cctggtctac cagggctggc agccctccag gaaaccagcg     2400

cctgttgccc tcgcccccca agttctgggc cacacaacgg actctgtgac actggagtgg     2460

ttcccaccta tagatggcca tttctttgaa agagaattgg gatcagcatg tcatctttgc     2520

ctggaaggga gaatcctggt gcagtatgct tccaacgctt cctccccaat gccctgcagc     2580

ccatcaggac actggagccc tcgtgaagca gaaggtcatc ctgatgttga acagccctgt     2640

aagtccagtg tccgcacctg gagcccaaat tcagctgtca acccacacac ggttcctcca     2700

gcctgccctg agcctcaagg ctgctacctc gagctggagt tcctctaccc cttggtccct     2760

gagtctctga ccatttgggt gacctttgtc tccactgact gggactctag tggagctgtc     2820

aatgacatca aactgttggc tgtcagtggg aagaacatct ccctgggtcc tcagaatgtc     2880

ttctgtgatg tcccactgac catcagactc tgggacgtgg gcgaggaggt gtatggcatc     2940

caaatctaca cgctggatga gcacctggag atcgatgctg ccatgttgac ctccactgca     3000

gacaccccac tctgtctaca gtgtaagccc ctgaagtata aggtggtccg ggaccctcct     3060

ctccagatgg atgtggcctc catcctacat ctcaatagga aattcgtaga catggatcta     3120

aatcttggca gtgtgtacca gtattgggtc ataactattt caggaactga agagagtgag     3180

ccatcacctg ctgtcacata catccatgga agtgggtact gtggcgatgg cattatacaa     3240

aaagaccaag gtgaacaatg cgacgacatg aataagatca atggtgatgg ctgctccctt     3300

ttctgccgac aagaagtctc cttcaattgt attgatgaac ccagccggtg ctatttccat     3360

gatggtgatg gggtatgtga ggagtttgaa caaaaaacca gcattaagga ctgtggtgtc     3420

tacacgcccc agggattcct ggatcagtgg gcatccaatg cttcagtatc tcatcaagac     3480

cagcaatgcc caggctgggt catcatcgga cagccagcag catcccaggt gtgtcgaacc     3540

aaggtgatag atctcagtga aggcatttcc cagcatgcct ggtacccttg caccatcagc     3600

tacccatatt cccagctggc tcagaccact ttttggctcc gggcgtattt ttctcaacca     3660

atggttgccg cagctgtcat tgtccacctg gtgacggatg ggacatatta tggggaccaa     3720

aagcaggaga ccatcagcgt gcagctgctt gataccaaag atcagagcca cgatctaggc     3780

ctccatgtcc tgagctgcag gaacaatccc ctgattatcc ctgtggtcca tgacctcagc     3840

cagcccttct accacagcca ggcggtacgt gtgagcttca gttcgcccct ggtcgccatc     3900

tcgggggtgg ccctccgttc cttcgacaac tttgaccccg tcaccctgag cagctgccag     3960

agaggggaga cctacagccc tgccgagcag agctgcgtgc acttcgcatg tgagaaaact     4020

gactgtccag agctggctgt ggagaatgct tctctcaatt gctccagcag cgaccgctac     4080

cacggtgccc agtgtactgt gagctgccgg acaggctacg tgctccagat acggcgggat     4140

gatgagctga tcaagagcca gacgggaccc agcgtcacag tgacctgtac agagggcaag     4200

tggaataagc aggtggcctg tgagccagtc gactgcagca tcccagatca ccatcaagtc     4260

tatgctgcct ccttctcctg ccctgagggc accacctttg gcagtcaatg ttccttccag     4320

tgccgtcacc ctgcacaatt gaaaggcaac aacagcctcc tgacctgcat ggaggatggg     4380

ctgtggtcct tcccagaggc cctgtgtgag ctcatgtgcc tcgctccacc ccctgtgccc     4440

aatgcagacc tccagaccgc ccggtgccga gagaataagc acaaggtggg ctccttctgc     4500

aaatacaaat gcaagcctgg ataccatgtg cctggatcct ctcggaagtc aaagaaacgg     4560

gccttcaaga ctcagtgtac ccaggatggc agctggcagg agggagcttg tgttcctgtg     4620

acctgtgacc cacctccacc aaaattccat gggctctacc agtgtactaa tggcttccag     4680

ttcaacagtg agtgtaggat caagtgtgaa gacagtgatg cctcccaggg acttgggagc     4740

aatgtcattc attgccggaa agatggcacc tggaacggct ccttccatgt ctgccaggag     4800

atgcaaggcc agtgctcggt tccaaacgag ctcaacagca acctcaaact gcagtgccct     4860

gatggctatg ccatagggtc ggagtgtgcc acctcgtgcc tggaccacaa cagcgagtcc     4920

atcatcctgc caatgaacgt gaccgtgcgt gacatccccc actggctgaa ccccacacgg     4980

gtagagagag ttgtctgcac tgctggtctc aagtggtatc ctcaccctgc tctgattcac     5040

tgtgtcaaag gctgtgagcc cttcatggga gacaattatt gtgatgccat caacaaccga     5100

gccttttgca actatgacgg tggggattgc tgcacctcca cagtgaagac caaaaaggtc     5160

accccattcc ctatgtcctg tgatctacaa ggtgactgtg cttgtcggga cccccaggcc     5220

caagaacaca gccggaaaga cctccgggga tacagccatg gctaaggaag gacaagaagt     5280

tgtcaaagaa ttcccaacgc caggacccac atccctttgg tattgatttc acagtcagct     5340

gctcaacgga atggcctctc cacaccaggg atccttagca cccaaccggt ctgcctttaa     5400

ttttacccag gaaggactca cattggggcg aatgaaccaa gtttcgccat gctggatgat     5460

gaaatggatt cccatcccaa agtctgagat ggattgcata tacagtgtgc agtcccagag     5520

cctcctaaaa ttctagccat ttgtcacaca accacagcaa gaaacgtgtt ctatatctag     5580

agtgtgccca tctgtgttta gtacacatgc atgcatacac acccatacaa acatctgtgt     5640

gagggcagtt ctggagatga gcagagagag accggaataa actcaatctt ttctttccca     5700

agctcctagc caacactatc cttgggagaa agaaatttgc agaaactgct aagaccaagt     5760

gtggagatgt caagctagtt cacactctga ggctcagaat atgtaggaca tgcacaattg     5820

tgcagtcctt tgggattgga agtgaaacag tctgtgatcc cctaccttct agggaactag     5880

gacctaggaa gaggtaaaga ttatcaggta tgcaaagcgc cccaattctt ctgctgccat     5940

gggggatttt accccaactc cagggttcga ggccaatctg agaatggctt aggattgcaa     6000

tgtcaaggta ttatatcagc cccttgcttg aggcttgagg tcataatatc cctctaggac     6060

ttacctgttc ccccagatct tgccttggga ccacatttgc tgctactttt cctgctgctc     6120

tatcctatac attgaataat ccaagatggt agaactaggt taggaaaaat tccacacaac     6180

caaacagtct gccttaaaag tgacccacat ttttccatag ctcctcactt tttagccctt     6240

ctgcaagaga aaaaccctca tgggtccaca tggtgagaag ttaagtttcc tgtaagtggg     6300

cctctcaccc tggaaaggag ttgagggaca tcagatgctg gaaccctcac tgaaagtcca     6360

gaatgtctaa gccagtgtta gattttgtaa acaagtggaa cagtgttaaa tttctatgat     6420

gttggagcca tccagagact actggaattg tcgagacttt tggattatta tccttatcct     6480

tatcctaatc ttcctagccc ttcaggctag agtaggcttt gatcctgaga accttgctgt     6540

tgctctgagg agatataatt ctgggagaaa gaatctttta taagaacagt acagattgtt     6600

ctcaagaggg ccatcagaag gaagccaaag agttcacagc ctcagcacca acaactcaac     6660

atggtcatca tgttttctat atggtttttc cagctagcag tactcccttc catacctgtg     6720

actgggcagt gcttttctct ctcccatgtc tagcctccaa aagttaagtg aaaattagtc     6780

aactgcacgt ggaagccccc accactttgg ggatctcttt atttcttttc agccagggac     6840

ctgtccactc cctttgaatt aatatgggaa gaaattaata caggatgaac tggagagaag     6900

ggttgagtgt ggcatacttt ctgaaacctg gagctgggaa ttgcggagaa gggaaggtct     6960

agactagtta catcacatag ggattactgt aaatcaagtc atctcaagtc tagtgaagac     7020

agccaacaga aacaaaacct agcataggga tagaaaatac catgcacgtg tgcagcccca     7080

cctaattcct gcatccaagg caggtgttgt taatctatca tagcacttaa aaaaaaaaaa     7140

aaaaagagac caaaaataac tttaggaacc accatattat atcactccca atagcactga     7200

cctggtgatc aaaaacactt gagaagacat ctattggcca tctctggcca attacactaa     7260

gaaacatatc aaggtgcttt tggcacaggt gcccacaaat acggatgcag tgctgagata     7320

gtttatgaga cttgtaccat ttcacaaact ctgaaattgg gttccatatt ggcaaggctg     7380

ccacagttgt taagaataat cctctatgtt tcttcctcac aaaaccatat ctcatttata     7440

tccagaccat tacttcacta taattacaag gacaaattat tagcaagaaa taagaatagt     7500

attagaagaa ttgatcctat tttgaacccc tctccagtat cttcacactc ttgtcaactc     7560

tccaggcctc tctcttgccc tgagttatca gcctgtgtgg tgttaactac cttagaaggt     7620

acaagctaag aaatgtaaca gtatcaaccc tcccagttgc ttaattatac ccataggtaa     7680

tacaaaaagc tctgaagacc caaagatgac attactaatg atgtgatttc aggagccaca     7740

gaagaacctt accagcttcc ctcaaatcag tccttatcct ctttctatct tcactcccat     7800

catcatctat tttcacacta tccagctaag caaagattcc tggaggctga cttgtatctt     7860

cagactcaca gagtgaattc agctcttctg aatcaagacc cacccagtct ctttcattca     7920

gacctgttgc taacaaattt atatttgcca aggatattag gcaaaagagg ctacttgatt     7980

ggtggccaac ctcgtgccca catggaaggt atctttaata gggtcttttc aaaccttagt     8040

ggaggagggt cagctcaatt tgggcaatgc atttgttccc agtttcattt tcttcctggg     8100

aattaactcg tcatttcatt ccttcagtca tcttctgtgt aggtgaccgg agcactgaga     8160

ggcagctctg atgcactatt gtgtgtcagc agctcaaagg ccctaaaaca ctgaaggttc     8220

tgcatctgaa gtattagatt gttagcagca aaatatgaaa gatgaggtgg acagtcctct     8280

aagccctatt tagggaagct tttccaagcc acaatcttaa ctacctaccc aaaggatttg     8340

cattaccccc agattctgtg ccaacaacct tttaaggaaa tacagtcctt gggaaatgag     8400

ttttgatggt gaattggggt gttaaggaag ggaaagattg tcatagatgg tagggctttg     8460

aaaatgcagg gtatcagctg ccactcctgg cttcaacaca ttgagtcact gcctagacgg     8520

ttctcttggt cttattccca tcctggccaa tgcttaaata ctatttgttg aaaataattc     8580

tttgagacag atttcagcta cctcccttcc aggttcgatt taacttggtt gtaattgtca     8640

atttgttgtt ataggtctta cctgtgtgaa agaaagaaaa agaaagaaag aaagaaagag     8700

aaaggaaatt ataaggtcaa gttaacagtt ttgaggtttt gtgttttttt ctggaactac     8760

ttcaagtgag aaaataaaaa aaaatggtga caaagctgta cagatagaga taatagaaga     8820

caaagagatt aaaaggaaat aaaaatgcat gattaaaaac taagaataaa aaacctattt     8880

ttatgtttcc taaaggaaat tgtttattct acagcctcag taggtagaca caaacataaa     8940

gatttcccta gaagacatag agtgggattt gataacactg tctgttattt tctgtacatt     9000

gtggtaggtc caggaaatat gacattttcc cccttgatgt gttattgttg ttgttgggtg     9060

gggtgggcat tttgtttatt tgtttggtgg caatcagtgg tagtagggag tgggagggct     9120

tatattggtt tttccagcta ttaaggggac atattgtgtc gttgtgcttt tcacgttata     9180

aaatgtttat atttaccagt acagcactgg gctttataaa gactgcactc agaaccacac     9240

tgcacagtcc agttttttaa aaagctgcta catgacagac aggtaatccc actgagtgag     9300

ttttgagaaa caaatcaaac gaagtaaaca agaaacataa aaaccaaata gcaaatgaat     9360

aaaagcctgt tcttgtaact tattcaactt ttgccaaatt cctaccaatc acttgctttt     9420

taaaagaaat gtataatagc caaaagagaa attatgtccc tgttgtacag aagttagaat     9480

ttttgactcc aggcagcagt ttgctcagtg atcttgaaca agttatccaa ttgcctctac     9540

atttgcatca gtttctctag ctgcaaaatg gggataatac tatataccta cctcacagtg     9600

ggagggcagg agattttgag gccctgaggt tttaggtggg ctgtgagggc caacgcttga     9660

cacaaagtcc atgggttatt attcaagaat gcacaggccc atcggccttt tagaaagaca     9720

agacagggag tgcttgtttg atatttcaag gaataaagcc ggagctcctg aattgtagtc     9780

caccttaaaa gagagacctg tattggagaa tattttattt ttttggcaaa tttgatctta     9840

ccctttacca gttctataat ttggttaaaa gctgattatg tcctacaatg tcaaagtcag     9900

ctaactgtcg tctacttaag acttctggtc atttccaact tatagaggaa gggagtctct     9960

aaaatctctt cttcagaagg cacctcactt ctcagactta aaattccaca tcaagtgttc    10020

cattaaaaga agataaggca ttctgagtgc aaacaaatgg gggcttctta aactacacac    10080

cagcagtcag tgaggaaaac tttgaacaat tattgagttg ctttcttggg tctctataat    10140

caataacctg tctgcagata tctatctata taaagatatt atatataaat ataaatttac    10200

atatatatgc acatgtatat atagttgtac atatatgtgt gtatatatat acttaaatgt    10260

aatatttaca aaataaaact gtgatctcgt ctagagaaaa tgtattcata ttacaaactg    10320

ctcttccata tttatgtacc atattatacc tttttattat tgttataatt attatgggta    10380

tttctaatta atatgatgtt gaaacctgtt tggcaccttc tggaagctac caaaaaaatg    10440

acactccatt gaagtgctta aaagctgttc tcataagaat tcttctggcc tattgtaaaa    10500

aagaaaaaaa aaaagaaaaa gaagaaagac acaaagaaaa taatctaaac accaaaaact    10560

aaacacaatt ccaatccttt ttctgtacct cacgcgcata aatttgctgc tcctattttt    10620

ttttctgttt atgtgttttt atggatctaa gttaaatctt ttggcaatat ataaaaatgt    10680

aaatagtaaa ctttatttat taagaatgtc atctttttta atttatattt acacaattgt    10740

tcatctaatt tattttttct atacagtttt aaatactcag acatattttg ctgttcatga    10800

tatttttatc ctgttctcat ggatttgttt tcccatactg ttttctctga tctcaattac    10860

aggttggatc tcacaaataa taatgtcaga gacagaaata ttttgccact gttgattact    10920

atactttaaa gttctatatt atgaaaatat ataatagctt gtacgcttca aaaaaaaaaa    10980

aaaaaaaaaa aaaaa                                                     10995


<210>  1558
<211>  3739
<212>  DNA
<213>  homo sapiens

<400>  1558
gcgacgctgc cgggtccgcc gcggcgctgg cggcagtggc cggtgtgagc gcagagccgg       60

gccctgggca gcagcggcag cgcggtagga cctcgcgcag cgtccgcggg ctccggggcg      120

ggggcgccag cggcgaagcc ccctccccgg ggaggcggga cctgggggag ctcccgagcc      180

ggggagcggc ggcggccggg aacgatgcat cagaagctgc tgaagagcgc gcattacatc      240

gagctgggca gctaccagta ctggccggtc ctggtgcccc gtggcatccg cctgtacacc      300

tacgagcaga tccccgggtc cctcaaggac aacccgtaca tcaccgacgg ctaccgggcc      360

tacctgccgt ccaggctgtg tatcaaaagt ttgtttattt tatctaatga gacagtaaac      420

atctggagtc atttgctggg tttctttctc ttcttcaccc tgggaatata tgacatgaca      480

tctgtgttac cttcagcaag tgcgtccaga gaagattttg taatttgttc tatttgtctt      540

ttctgcttcc aggtctgtat gctttgctct gtgggctatc atcttttttc ctgccatcgg      600

tcagaaaaaa catgtcgaag atggatggca ttagattatg caggaatttc tattggaata      660

ctgggctgct atgtctcagg agtattttac gcattttatt gtaataacta ctggcgtcag      720

gtgtacttga tcacagtgct tgctatgatc ctggcagtgt tctttgcgca gattcatccc      780

aattacctca cgcagcaatg gcaaaggctc cgttctatca tcttttgttc tgtttcggga      840

tatggagtga ttcctactct tcactgggtt tggctcaatg gaggaattgg tgctcctatt      900

gtacaggact ttgcaccccg tgtaattgtg atgtatatga ttgctcttct tgctttccta      960

ttctacattt ccaaagtccc agagcggtac tttccaggac aactaaacta cctcggatca     1020

agccaccaaa tatggcatat ccttgcagta gtgatgttat attggtggca tcagtcaaca     1080

gtgtatgtca tgcagtacag acatagcaag ccttgtcctg actatgtttc acatttgtga     1140

attaggtatg gccacctggt gaattcagtt gttaagcaat atataatggg gaattgtata     1200

ccccactatt tctaagattc ccattagttt tccctttttc ctttttaata tgagtaatgc     1260

tttataaaaa tgggaaaaaa agtatactta aggatctgta gtaataactg ctttacaaaa     1320

tccttaaaac tactaatttg ctgcttgtac agaaagtgaa aattagttgg caatcataag     1380

aaacatctga ataacaacga tgaatgggaa actagtgttg aaataggatt cattttactt     1440

agcaccagct taatttcctt aggaagggct catgtccatt agaaaatgga gtcatcttat     1500

gtgcttaatt attttcagtt aattgtcaag tttaagtgcc taatcaaggc aagtgttgtt     1560

tcagcctatg cttaatgcaa gctaggatag tgattttaaa taatcactaa aatcactaga     1620

tttaaataat cactaaaatg atttgtgaga aactggcact tcagatatta tatcctttag     1680

ctataggttc ttctctccct aagaacatta gatattttag ttttccagaa caaaagcttt     1740

aaacttctgc agtaagttga gagaagggtt gagaagagga aaagaacttc tcattttcta     1800

tcagataaga atcacattag aaactaagta caagattaga caacaaatta tgtggtcaaa     1860

taatatagtc attagccacc taaacatttt aattccagat attatttaat tccatataat     1920

aactgaattc ttgtgagtgg attacaggtt tttgatccca aaattccaga gctttcaact     1980

ctctgaattt gtagtcctga atatcccagt ggtgggggtt cccagcattg tgggtgctac     2040

ttgcaaggcc atagaatcta gatggccctg tcttgaccct gaaatgaacc ttaagcctta     2100

gaacaaagtc atgcagatgc cccatttgat aataatctta ttcacctgtg ctctggtcct     2160

cggtttctgc atgtgttagc attgcattga taactcagaa tcttgataaa cacttaatat     2220

ttgggcctga agcattaaac tttcttttta ttgtatatac ttaaaaaata gaactcactg     2280

ccctatcata cattgtagcc ctcttattct ttggtctttc atatgcatta gttaaatccc     2340

ttaaagtaga cattcataaa aacttacatt gtttattgga gtataaaata ttacccaagt     2400

ttcttcatga gttgacatga gctgttttaa atactggtgt attttcagaa cagtaaaatt     2460

actgaatatc agaaaaaatg ttaattgatg atgaagctta ttcccaaaat gccttttgtg     2520

catatgatac ttggaaagtc actaatgtgc ctcagttaat acatcagtaa aatgttgtgt     2580

ttcttttcca gtgtagtgtt tttggaatat aaattcccca tgctagtata gtatctcagc     2640

aaagagaatt tccccccagg aggctcagta aaggaatacc gtgtcttacc catcgttatg     2700

atggaaggct gctttgaaaa tggctgtttt accttataag gttaaaattt tgatccatat     2760

gttaagtgat agaagatttt ggtgcaacag tagtaggata tatttctcct agaacatccc     2820

ttattggctt acatgatttt attgcctttt aatagatatt ttgtcatttt ggccaaacaa     2880

aagacactga gtagttacac ttaagttaaa aatgagggga aaatcattat tttaggtgtg     2940

gagccatttt tattataaaa ctttctcaaa ataaaaaaac attgaatcat ttcaattttt     3000

gcagtccctg tattagtata tgaatacata cttgccattt gaattaataa catgaaaaga     3060

gtatactgtg tttttaaatc cgtgtttctt tgaatttaaa gggtgtacag gtctttctgt     3120

agggaaaatt attccatgta aacatttcaa ctctgtatga aaatgttaaa tattgtaaga     3180

aagttatcct ctcatttttt cactgctatg atatatttat tataaaatag ggaatgaatg     3240

aatgaatatg gattgctgtt aactagaaac acttctgtat gtcagtcagc atttaatgac     3300

cacctactgt gtgcacagca ctactggtaa aattttgaag acattgttaa cattaaaaaa     3360

tattttaaag ttgtctacaa atctgagcct tgtaatgatg tatatttaag ttatttttgt     3420

ttttatagat taaagtaaga ttaaaatata ctatccagtt ttattactaa aaaagactgg     3480

ttttaatttt accaatgtgt gaactataaa agctttttgc ctacagattt tacattttaa     3540

aattatctat ggctgtttta aattgtctag caatttatat ggttgtggtt aactcattta     3600

agaaacaatt atctttctat attaagccat tttcaaatag caagacagtg cttgtctttt     3660

tttgttatta cactaactgc aattcagtaa gctgcatgac aaaatatgta ttatgtaaat     3720

aaactgggtt tactaaata                                                  3739


<210>  1559
<211>  6482
<212>  DNA
<213>  homo sapiens

<400>  1559
ggcggctgcg gcacctttaa gacaagggag gacccctctt gccctcggag aaaccaggaa       60

gggagtcgcg agcatcatac ggggctttgg ctgtactgta cagttactgt aggggcagtg      120

acgccgccgc cgccgcgcga gggagcgacc agggcagcgc gacgcgggca gagcgagcgc      180

cgcggacccc ggaggcgagc ggccgaggga gcccagtccc aacttcgggc cccggccccg      240

cgcgccccgg cccggccccg cgaggtctcg gcgcggaaga tggccggcgg cgtggacggc      300

cccatcggga tcccgttccc cgaccacagc agcgacatcc tgagtgggct gaacgagcag      360

cggacgcagg gcctgctgtg cgacgtggtg atcctggtgg agggccgcga gttccccacg      420

caccgctcgg tgctggccgc ctgcagccag tacttcaaga agctgttcac gtcgggcgcc      480

gtggtggacc agcagaacgt gtacgagatc gacttcgtca gcgccgaggc gctcaccgcg      540

ctcatggact tcgcctacac ggccacgctc accgtcagca cagccaacgt gggtgacatc      600

ctcagcgccg cccgcctgct ggagatcccc gccgtgagcc acgtgtgcgc cgacctcctg      660

gaccggcaga tcctggcggc cgacgcgggc gccgacgccg ggcagctgga ccttgtagat      720

caaattgatc agcgcaacct cctccgcgcc aaggagtacc tcgagttctt ccagagcaac      780

cccatgaaca gcctgccccc cgcggccgcc gccgccgctg ccagcttccc gtggtccgcc      840

tttggggcgt ccgatgatga cctggatgcc accaaggagg ccgtggccgc cgctgtggcc      900

gccgtggccg cgggcgactg caacggctta gacttctatg ggccgggccc cccggccgag      960

cggcccccga cgggggacgg ggacgagggc gacagcaacc cgggtctgtg gccagagcgg     1020

gatgaggacg cccccaccgg gggtctcttt ccgccgccgg tggccccgcc ggccgccacg     1080

cagaacggcc actacggccg cggcggagag gaggaggccg cctcgctgtc ggaggcggcc     1140

cccgagccgg gcgactctcc gggcttcctg tcgggagcgg ccgagggcga ggacggggac     1200

gggcccgacg tggacgggct ggcggccagc acgctgctgc agcagatgat gtcatcggtg     1260

ggccgggcgg gggccgcggc gggggacagc gacgaggagt cgcgggccga cgacaagggc     1320

gtcatggact actacctgaa gtacttcagc ggcgcccacg acggcgacgt ctacccggcc     1380

tggtcgcaga aggtggagaa gaagatccga gccaaggcct tccagaagtg ccccatctgc     1440

gagaaggtca tccagggcgc cggcaagctg ccgcgacaca tccgcaccca cacgggcgag     1500

aagccctacg agtgcaacat ctgcaaggtc cgcttcacca ggcaggacaa gctgaaggtg     1560

cacatgcgga agcacacggg cgagaagccg tacctgtgcc agcagtgcgg cgccgccttt     1620

gcccacaact acgacctgaa gaaccacatg cgcgtgcaca cgggcctgcg cccctaccag     1680

tgcgacagct gctgcaagac cttcgtccgc tccgaccacc tgcacagaca cctcaagaaa     1740

gacggctgca acggcgtccc ctcgcgccgc ggccgcaagc cccgcgtccg gggcggggcg     1800

cccgacccca gcccgggggc caccgcgacc cccggcgccc ccgcccagcc cagctccccc     1860

gacgcccggc gcaacggcca ggagaagcac tttaaggacg aggacgagga cgaggacgtg     1920

gccagccccg acggcttggg ccggttgaat gtagcgggcg ccggtggagg aggtgacagc     1980

ggaggtggcc ccggggccgc caccgacggt aacttcacag ccggactcgc ctaaaaacca     2040

aaaagagaaa acagaaaccc gagaaagaga gagacagaga gagagaaaaa aaatcaccca     2100

ccaccccccc aaaaacacaa aaaaagaaaa tctatctata tacagatatc tatatctata     2160

tatatatata cagatatata tatatgacgc gtcacagaat ctagggtagc gctttctcag     2220

atttccctcc tttctgacgt ttttctccct ccgcaggggc cccggccctc cctggctccc     2280

cttcccccca ccaccccatc gctgggtttc ggggcttggt ttggggtttt ttgtaggaca     2340

caaggaatcc gagaccccgc acagccccct gggcacccgg catggggcct ggggcccgat     2400

ccgaggccct gggctggggg gagggtagac gtgggggcgc tgggggggga ctggggtggg     2460

cttttaattt cctcccctcg ctggtttcta tgagtctttc agacaagacc ttaaatgatt     2520

tctgtctgct ctgagcggac gttaaaatgg gcccccgtcc cccgacccgc accctccttc     2580

ctcagggcac ttactaaggg aggggtctcc ctctccatct ccccagtggc ctccccgcct     2640

ccaaccctgc ctgcggcctc cccccgtcgc ccaccccacg tctcctggcc actgagacac     2700

aaacctattt atttctaggc ctggagaaag gagatcggac tggggttccc ggtggggcgc     2760

caggatggct cctgggggtg ctcctgccgc cttccttcac ggcacttaca accggcggga     2820

cccccaggga ccacccctca gggcgccccc ccacccccgc ccggtccacc tagaccccca     2880

cgtttggaga ttcaaaactt ctgtcttcgt cctctccccc gagccccctc tcccaaattt     2940

ttaaagcact ttttagattt ttttttctct ttcctcctta aaaacaaaat ttatatatag     3000

atatatatat atatataaat aatatacttt tcctcagagg agcaggcaac agtgtgggat     3060

aaacagagtc acgatcagag gaaccccagg gtctggtgat ggcagggatg gggggagaga     3120

gagaaaatcc acaaattcca atgtcacaaa agcaataaaa caaactagaa aaaaaaaagg     3180

ttttacaaaa tgaaaggaag gaaaaaaaaa aaggcaacca accacattag aagtcttggc     3240

actttgtaac ggaacgggta ctacacttta tcttaattct taatttaaaa acatgtttac     3300

aagttacaac caacttctat gaaaagttga aaagacaaaa aaaaaaaaaa aaagcgagcg     3360

agagagagag cgagagagag agcgagagca gaagaaattc ctaaaagtcg atttattttt     3420

gtacaaaata ataaaaaaaa aaacccacca caaacgtaga atccacttct gttccccaaa     3480

aagcgagaag gggggttcag gaggaagcca tcgcagggga cctgggagac gccccgaggt     3540

gtttgtgctt cacccccaga cgtcagcctc gaaggcagga ctgtggggtg ttcgtgctgt     3600

gttccccccg ctcccccttt ctgtcccctt ttttggttct gacgtgaaga ggtcttagcg     3660

cccgcttctg tccacggggt ctctccttcc tcctccctag ctcagggatg ggccttccag     3720

ccggagcacc ccgatcccca tccggcaccc cccaatcccc caacacgcct gtccctcccg     3780

catggccacc aaggagctgg accttggatg cgcctaccct gctgaggtgg gtgacagggg     3840

ccccccacct ccagggcctt agaaccaccg cccctctccc caccccaggc acccctcttt     3900

ttactcaaag gcactgactg taatccaggg ggactgggac ctgcctcccc ccaacctctg     3960

gctcccacaa ggcccggtgt tgaccgagcc acaggccacg gacaggggcc ggggttgggg     4020

agactatgtc gccagatgcc aggacgccct caccccgttt gcatatgcaa tgctagcatg     4080

ggaccccgaa aatagacgct ctgctgcact gagacttctt gtcaatgccc aaccggcggg     4140

ggggtgtctc cctgcccccg acccccccat acccccttct ctgtgacaca cacatcttct     4200

cgtctctttt tctttcattg ttaaagggaa gctttttaag aaggcaattt tcatattgtt     4260

tctacaggat ggttttggtt cccttccctt cccacccccc cttaagcctg tcagccccct     4320

ccaaatgtct caggatcccc cctctcccct ggggctgggt gacagcaccc cggctgcgtt     4380

cacaccccag tgtcacaggg cgagctgttc tggagagaaa accatctgtc gtggctgagc     4440

ggggagcttg aacacccagg ccagggacac ccctccccag ctcccagaga ggccccctga     4500

ggggtgagcc ctctttccac cttcccctat ccatgcaccc cctcgcaata aaaccaactc     4560

taaaatcaca gctgtcgtcc tagccagtgg gggcgaccgg acttgggggg tggagccctc     4620

tgggacttcc gtaggaacaa gggctgcggc ccaccgcgac acttacacag acctcgggga     4680

ttgcactaaa ccctcgttcc tagctccgca ctcagcttcg cctgtcctgc ccgcccactt     4740

tgccttaact acccgcccgt cctgggggcc acagcctctg catgggccca gagccgggac     4800

ccccccagcc cagccccgcc ctccccagac tccgcgcaat cacatactgt atatagacgt     4860

gaatcgattt tatttttatt ctttaaatta aggtcgtgat aaagtgttgc caaagatacc     4920

tgctgaattc tcgcgtttca ggaaacaaac aaacaaaaaa aaatgatatt tgaggagggt     4980

cgtgttgact ccatatgaaa ggacacagct caaagctttt ttgtttggtt gtttggggtt     5040

ttttgtgttt tctttttttg gggtgttttt tttttaactg cctggtacaa aaaaaaaaag     5100

agaaaaaaaa aaaagaaaaa caatgcgaaa ttgttatttc cattctcatg gtgaagttgc     5160

gtggacgcgt gtgtgcgtgt gtgcaagaga gcgggagtga ggtccaggct ggggttgggg     5220

ggcttcaggc gggggcgccc gggggccggg gaggtggccg ggccggagcc cccgtctgca     5280

gtgcccccca gcctgccggg cccaggagag agagagaagc atctttgcta ctagctgttg     5340

ctgctacctg cctctgcccc ccgacgcccc ccgccttttg agattaagga aaaaaaaaaa     5400

aagtcaaaaa agtttttaaa aatgaaaaaa aaaaattata aaccagtgaa tgtaaaatgc     5460

cggagcaggc ccggcctggc atgggtgtgg acctgcagcc aggcaggctc gagcgggcga     5520

taccaaagtc tgccccccca ccattgtggc catgcagtcc tgtcactgtc tttttgcttc     5580

cttccgaggg gggtccccca gcctcttcca gggtcttccc ctggaagtgg gcggctgcag     5640

ggaaggtggg ggacaggggt ctttgcacga ttcagacccc ggggccgtgg caggagcggt     5700

cacctcacag gtggtgacac tgaggcaggg gcctcggggt gccccctccc gcccggcaac     5760

cagaatggtt ggaggcaaga cagagagaat gaaaggaaaa acagaagaaa aaaaaatatt     5820

aaaaaccaac aaaaaaagca aaaatcctat tttttgagaa agaaagatat ttatatttgc     5880

agttttattt taaaaagtta tttaagttga agcagccttc ctggaggtgg gggggggggg     5940

gtggtgggtg gctggcgcag gacgggtcag gggcctggag gctgggggtg ccccaggagc     6000

tacaacctca gagttaagac tagctcgcat taaatacata gatttacggg gggggggggg     6060

gggggccggg cccagggggt ggagggggcc agggagaccc ccatccctcg ccggggctgc     6120

ctggaggctg tggaccagga tccgatgccc aggtcccgcc ccccacccca ccccaggccc     6180

agaatcgagg tgccttggac tttggagggg ccaggcctgg tgaatggggg gcggggcggc     6240

gccctcaggg tacagagcac agacagatag acattccaga gactgtattg agagtcttta     6300

taaagtgtgg gagatttaaa aaaaaaaaaa actgataaaa atgcactttt tgggagtggg     6360

gagggagaag ctttaaaagt aataaaaaac aaacaaaaac acaaaagatg aaaaaacaaa     6420

aaaattcatt tttcttgtac ataaaaaaaa aaaaagaacc actaaacgca gcctgttacg     6480

ac                                                                    6482


<210>  1560
<211>  5238
<212>  DNA
<213>  homo sapiens

<400>  1560
acacacacac acacactcac aggctcattg gcagacaggg ccacaactcg cggctctagg       60

gaaggccaca gacctcagct gtacgagcgg aacctggact agaggaactt tcctcaggac      120

tcagggcaca cagcccctcg gccactactg tctgcgagcc cgaggcgcag gggagcgcca      180

gcggctgcag gtacgctgcg cacccgcact ggggcctggg cggtgcagcg gcggcgggag      240

ggtcctggga accgcagccg ccgaggccag tgtgtgagcc ggccggccgc ggcaagccgc      300

atcccccggc cgcccctcgc agccccttgc tccccggcag ccgccgccgc cctcaggcag      360

cccagccggg cgctcgcgcc aggacttccc cgccgcccgc ctcggcccgg aacatggctg      420

cgcgccctgc tgccaccctc gcctggtcgc tactgctcct ctcctcagcc ctgctccgcg      480

aaggctgccg agcgcgcttc gtcgccgagc gggactcgga ggacgacgga gaggagccgg      540

tggttttccc ggagtcgccc ctgcagagcc ccacggtgct cgtggcggtc ctcgcccgca      600

acgcggcgca cacgctgccg cacttcctcg gctgcctgga gcggctggac taccccaaga      660

gcaggatggc catctgggca gccactgatc acaatgtgga taatacaaca gaaatattca      720

gggagtggtt gaaaaatgta cagagactct atcactatgt ggagtggagg cctatggatg      780

aaccagagtc ttaccctgat gaaattggac caaagcactg gccaacctcc cggtttgccc      840

atgtgatgaa actacgacag gcagcccttc gaactgcgag ggaaaaatgg tcagactaca      900

ttctgttcat agatgttgac aatttcctga ctaatccaca gaccctcaat ctactgattg      960

cagaaaacaa aactattgtg gcccccatgc tggagtctcg gggcctgtat tctaatttct     1020

ggtgcggaat cacccctaag ggcttctata agaggacccc agactacgtt cagattcgag     1080

aatggaagag gacaggctgc ttccccgtcc ccatggtcca ctccaccttc ctaattgacc     1140

tcaggaagga ggcctcggac aagctgactt tctacccccc acaccaggac tacacctgga     1200

cctttgatga catcattgtc tttgccttct ccagcaggca agcaggcatc cagatgtacc     1260

tctgcaacag agagcactat ggctacctgc ccatccccct gaagccccat cagacactgc     1320

aggaagacat cgagaacctc atccatgtgc agattgaagc aatgattgac cgtcctccaa     1380

tggaaccctc ccagtatgtc tcagttgtcc ctaaatatcc agacaagatg ggatttgatg     1440

agattttcat gataaacctc aaacgcagaa aggacaggcg ggaccggatg ctgcgcacac     1500

tgtatgaaca ggagattgag gtcaagattg tcgaggctgt ggatggaaag gcactcaaca     1560

caagccagct gaaggcactg aatattgaaa tgctgcctgg ctatcgagat ccctattcct     1620

ccaggcctct aacaaggggt gaaatcggct gctttctcag ccactactca gtctggaaag     1680

aggtaattga tcgagagcta gagaagactc ttgtaattga agacgatgtg cgttttgagc     1740

atcagtttaa gaagaagctg atgaagctga tggataacat tgaccaggct cagctggact     1800

gggaactgat ttatattggt aggaagagga tgcaagtaaa ggagccagag aaagcagtgc     1860

ccaatgtggc aaacctggtc gaagccgact attcctactg gaccctgggc tacgtcatct     1920

ctctggaagg agcacagaag ctggttggag ccaatccttt tgggaagatg ctgccagtgg     1980

atgagtttct gccagtcatg tacaacaagc atcccgtagc cgagtacaag gagtattatg     2040

aatccaggga cctgaaagcc ttctctgcag aacccttgct catctaccct acgcactaca     2100

caggccagcc ggggtacctg agtgacacgg agacctccac catctgggac aatgagacag     2160

tggccaccga ctgggatagg acacatgcct ggaagtcccg gaagcaaagc cgcatctaca     2220

gcaatgccaa gaacacagag gccctgccac cgccaacctc cctggacact gtgccttcaa     2280

gggatgagct atgaaggctc cctgggagtg tggcccacat cagttcaaca tcctctggtt     2340

tttctaaagg gctattcatc tgtttgctcc agttttctgt tttgttttgt tcttagtggt     2400

cacagtcatc taaccaaagt gatctagtgt gatagatcga aattaacata tttttgacca     2460

tggaaggaaa taaggaaatt caacccaaat ttcccaagac ggctgaaaga caggtttttt     2520

ggaaactgtt aagataaact gtaatccaga cacctaattc ttcagttcac tactcatgtg     2580

atactgattc ccacattaag gttgaacaac atggctcaga gtcttgttca agagaaagtg     2640

atcaccgagc tgtcacatca gcaaatatgt agtcaaggca gccaggccaa ctagaccaca     2700

cttattggtc tagtttgtcc gttttatatg acattgaaaa cttgtgtgtg caacttttgg     2760

gggacaggaa tcacttaaaa tcatatttat ttggcttttt atttaaagga ttctgtcaca     2820

agtcttattg aaaagtagat tttttaaaaa aaaaaaatct tagtccctgt tatccagtag     2880

gggtgggtat ttgggtccga ctgagacttg gcctgtgacc atcatggcag ttggagttct     2940

catatagagg tgaccagttt gccatgtgga tataatttag tagatatttg acagtttgtg     3000

taggtatttg agggaaaaaa ctcaatgttt ggctttttta ttatggccac tcgagtcagg     3060

atgctctatt tataaagata aatgtaatat ataaagggtg aggactggct gtgcatcctg     3120

ccctgtcccg ggtttgcgcg ctgctacaga gcttcacgct ctccgctcca ccccttagcc     3180

tgggaaccca ccgcaggtgt gagttctgtg agtcactgct aagagacaga gcacattttc     3240

aggccagcaa ctatccttgc cagagttttt tcattatatt ttgaattatt tattttacaa     3300

aatgggcgaa gatattgtct ttaggataag gcagagaaac agatgttgca gacttccacg     3360

gcacccgggg gagtggtggg tgtggacaca ttggttcggc aatctgattc tcctgaattt     3420

cccagccagg ctcttgtggg gaggcctgtg gatgggggga tttgaactat ttggaaacaa     3480

atgattctct atctcaggtg agaaacctgg tcagaaacaa agggctggtc acctgattta     3540

ggccagcaac cagggaagct cttagaatcc caggcggaca ccctttctca aaagatatcc     3600

cctaagagtc ctttctgctt tcttcacaga ttgattttat gtaaaatgca gagttggact     3660

acacgatttc ttcccactcc acaatctgtc atcctagtat agatcatggt ggtttccctc     3720

aagtttatgt tctcatgccc tcaatctgta aatttttgtc tccagaaaaa ccctcccagg     3780

catcccatac cagcaccgtt cctcatcact gtccatgcac catgcagcca tatggggggc     3840

cgtgcacacc ccaaaccctg agcttcacac ttaaactcat ggggagggcc cttcagagca     3900

gagtccacag gcgggtggtg ctacatacac aagcttagtg tacgagtgta agatacactt     3960

taagccagac acctaattct tcagttcact gcccatgtga tactgattgc cacattaagg     4020

ttgaacagca tggctcagag tctagagaaa gtgatcacca agctgtctca tcaccaaata     4080

ggtagtcaag gcagcctcat ctccccaggt gaggggcggg tccccacttt aggacaagag     4140

gcagcttgcc ttccaccaga cgccagcctc ggccttcctt cccgactcac tgtgggtacc     4200

cttctacact gaccagcaag ctaggccgct ggaggaaagg gaactcaccc aactctaaat     4260

tgtgccgctt agacttagct gtcagtgtga cttcctttcc cacccacccc cagaaaaaca     4320

gaaagagcat ctggggagcg agtgaaaatt ccttaggtga ttcctaagat ttccttgggt     4380

atctggtttt tgttttcata tttgagtgtg tgcatgtgtg catgacttta atgacttttt     4440

taatggggtg ggaggtggct ggggtgctgg ggttgaagga agtttgggtt gatttttgtg     4500

gtgttttgtt taatagagaa tttttttttt cctgttcccc tgtcagctgg tctgacagat     4560

ttaagaactc tcattcttaa aagactttgg acttaaattc tagcatttta gactaggact     4620

gttctactgt gaagaaagtt ctgtctcctt tagcccggtt tgtttctccc tgctcaggtc     4680

tagaatccca agcagtgttc ttttctggtg aacactgtga gccgcagatg tgactttttt     4740

tttaaagtca tctcttcagc aatccagagg ttccttgacc tcattatttg tcctatctct     4800

cccttatagt cctaagccaa gacatttgac ctttgacatt tgacctttgc agtgtcatgt     4860

gagggcgtca gtatagaggc ctttgcatct gggcctggca cccgctctct gcctctggag     4920

gctaaaccct gtctggattt ctcttgggat ctaacgtggg atcttctgga cagacaaccg     4980

tgacatcagc agtgctggtg ctgctgtgtg tggactgaac acctgcactt tgcagaggac     5040

acgctgcatg ggccccgctt gcggttcatt caggcctgct gcaggagctc tgagaacaag     5100

aaagagtgga cacccgttcc cctgcatcat ctgtcttgcg tgctatttca gagtggggaa     5160

gtgataaact atttgccttc tggagctctt tgtgaaaaat taaaaaaaaa cttagctcaa     5220

agaaaaaaaa aaaaaaaa                                                   5238


<210>  1561
<211>  5467
<212>  DNA
<213>  homo sapiens

<400>  1561
agttccggcc catgttgttt cggccgagga gccgtcgccg ccatttcaag accgtactag       60

gtagatggtc aattagagtt cccagggttt gaagcctgta actgctgccg ccgctcaagc      120

cctccagagc attgctacgg ctgctgccct tgtactacta cctccaaata cgttcttgct      180

ggtagtggcg gcagcaggac caattacctc ttttttgctc tccctcgaga agctccagat      240

ggcgtcttcc gtgggcaacg tggccgacag cacagggtta gctgagttgg cacatcgaga      300

atatcaggca ggagattttg aggcagctga gagacactgc atgcagctct ggagacaaga      360

gccagacaat actggtgtgc ttttattact ttcatctata cacttccagt gtcgaaggct      420

ggacagatct gctcacttta gcactctggc aattaaacag aacccccttc tggcagaagc      480

ttattcgaat ttggggaatg tgtacaagga aagagggcag ttgcaggagg caattgagca      540

ttatcgacat gcattgcgtc tcaaacctga tttcatcgat ggttatatta acctggcagc      600

cgccttggta gcagcgggtg acatggaagg ggcagtacaa gcttacgtct ctgctcttca      660

gtacaatcct gatttgtact gtgttcgcag tgacctgggg aacctgctca aagccctggg      720

tcgcttggaa gaagccaagg catgttattt gaaagcaatt gagacgcaac cgaactttgc      780

agtagcttgg agtaatcttg gctgtgtttt caatgcacaa ggggaaattt ggcttgcaat      840

tcatcacttt gaaaaggctg tcacccttga cccaaacttt ctggatgctt atatcaattt      900

aggaaatgtc ttgaaagagg cacgcatttt tgacagagct gtggcagctt atcttcgtgc      960

cctaagtttg agtccaaatc acgcagtggt gcacggcaac ctggcttgtg tatactatga     1020

gcaaggcctg atagatctgg caatagacac ctacaggcgg gctatcgaac tacaaccaca     1080

tttccctgat gcttactgca acctagccaa tgctctcaaa gagaagggca gtgttgctga     1140

agcagaagat tgttataata cagctctccg tctgtgtccc acccatgcag actctctgaa     1200

taacctagcc aatatcaaac gagaacaggg aaacattgaa gaggcagttc gcttgtatcg     1260

taaagcatta gaagtcttcc cagagtttgc tgctgcccat tcaaatttag caagtgtact     1320

gcagcagcag ggaaaactgc aggaagctct gatgcattat aaggaggcta ttcgaatcag     1380

tcctaccttt gctgatgcct actctaatat gggaaacact ctaaaggaga tgcaggatgt     1440

tcagggagcc ttgcagtgtt atacgcgtgc catccaaatt aatcctgcat ttgcagatgc     1500

acatagcaat ctggcttcca ttcataagga ttcagggaat attccagaag ccatagcttc     1560

ttaccgcacg gctctgaaac ttaagcctga ttttcctgat gcttattgta acttggctca     1620

ttgcctgcag attgtctgtg attggacaga ctatgatgag cgaatgaaga agttggtcag     1680

tattgtggct gaccagttag agaagaatag gttgccttct gtgcatcctc atcatagtat     1740

gctatatcct ctttctcatg gcttcaggaa ggctattgct gagaggcacg gcaacctgtg     1800

cttagataag attaatgttc ttcataaacc accatatgaa catccaaaag acttgaagct     1860

cagtgatggt cggctgcgtg taggatatgt gagttccgac tttgggaatc atcctacttc     1920

tcaccttatg cagtctattc caggcatgca caatcctgat aaatttgagg tgttctgtta     1980

tgccctgagc ccagacgatg gcacaaactt ccgagtgaag gtgatggcag aagccaatca     2040

tttcattgat ctttctcaga ttccatgcaa tggaaaagca gctgatcgca tccatcagga     2100

tggaattcat atccttgtaa atatgaatgg ctatactaag ggcgctcgaa atgagctttt     2160

tgctctcagg ccagctccta ttcaggcaat gtggctggga taccctggga cgagtggtgc     2220

gcttttcatg gattatatta tcactgatca ggaaacttcg ccagctgaag ttgctgagca     2280

gtattccgag aaattggctt atatgcccca cacttttttt attggtgatc atgctaatat     2340

gttccctcac ctgaagaaaa aagcagtcat cgattttaag tccaatgggc acatttatga     2400

caatcggata gttctgaatg gcatcgacct caaagcattt cttgatagtc taccagatgt     2460

gaaaattgtc aagatgaagt gtcctgatgg aggagacaat gcagatagca gtaacacagc     2520

tcttaatatg cctgttattc ctatgaatac tattgcagaa gcagttattg aaatgattaa     2580

ccgaggacag attcaaataa caattaatgg attcagtatt agcaatggac tggcaactac     2640

tcagatcaac aataaggctg caactggaga ggaggttccc cgtaccatta ttgtaaccac     2700

ccgttctcag tacgggttac cagaagatgc catcgtatac tgtaacttta atcagttgta     2760

taaaattgac ccttctactt tgcagatgtg ggcaaacatt ctgaagcgtg ttcccaatag     2820

tgtactctgg ctgttgcgtt ttccagcagt aggagaacct aatattcaac agtatgcaca     2880

aaacatgggc ctgccccaga accgtatcat tttttcacct gttgctccta aagaggaaca     2940

cgtcaggaga ggccagctgg ctgatgtctg cttggacact ccactctgta atgggcacac     3000

cacagggatg gatgtcctct gggcagggac ccccatggtg actatgccag gagagactct     3060

tgcttctcga gttgcagcat cccagctcac ttgcttaggt tgtcttgagc ttattgctaa     3120

aaacagacaa gaatatgaag acatagctgt gaagctggga actgatctag aatacctgaa     3180

gaaagttcgt ggcaaagtct ggaagcaaag aatatctagc cctctgttca acaccaaaca     3240

atacacaatg gaactagagc ggctctatct acagatgtgg gagcattatg cagctggcaa     3300

caaacctgac cacatgatta agcctgttga agtcactgag tcagcataaa taaagactgc     3360

acaggagaat tacccctata cctgagcctc aaccttctgg gggaaaggga actagataac     3420

atacttctta cttgtctgta cagtaccttg ttgcagatgg gtgatatata atggtaatag     3480

aatagcacag ccagacttgc ttcctgcatg gtagggagag acacaaaaga tgggaaactg     3540

cttttccaca aggaatctcc gtagaatttt gcggcgacca gatggtgcat aggtctggaa     3600

ggtctgatct cccttggtct tccatgggat ggttagtgtg gaggggagat atagattgtc     3660

cggccgcttt gtgattccat ggattgattc agtcttctgg attttttttt ctttatattt     3720

tgggtactgg agcttttaaa aatgtttggt ttcaggtatt tttattcatg tgaagtgtat     3780

atgattctct tgagataagg ttttaagcta aaatgttact ccctgtttta gtttctgaac     3840

tctgacagat tgacagggac tttgctggtg tagtcttttt ataggtttta taaaccactt     3900

gagcctatat cagtcgtttt agtgtctgac ctaatatttg gagctatcag tgctttgttg     3960

atttagatga tgactcaaga ttttttctgg tccatttccc atttcctttt cttccctgac     4020

ccccataccc tcacccttaa aattctcctg taactcaact aacaaaatca agcctgattc     4080

aaaacatcct agggtgtttt aaacacacca tctggtgcca aatgaagatt tttaggagtg     4140

attactaatt atcaagggca cagttgtggt actgtcattg ataataatat agtttttttt     4200

tttttcctaa ttttgacctg tttcaccagt gttttaccct tgactgcccc ttctatgctg     4260

cttccaaaag tgatagtgtg tgtaagattt ttaccttcct ttctaaagtt tttttttttt     4320

ttttttaagt gagtcctgtt cttcctattt ctttcagcag aaatgaaatc ccaggtaagt     4380

ataagtattc aagtatttga tcagtaagtc acagttatct ccagtgcatt aaataacctt     4440

catcaagaaa taggttatag gtaaaatctc tgaaggatca tctatgtatt caagtaatta     4500

ttttttagat aataactgtc ttctggactt ggtcttgaag tctgtacaga ttcagcctca     4560

gtagtagcga actgcactgc tgtttggttt ggagtacaaa ttagacttat agtcctcctg     4620

gaacttgagt tattaaaatc ataggaataa aattatggga tctcaacaaa gggtcgaggg     4680

tttgaggctt aaacaagcca acatatgaat atatgttttg tctcgctata ctgcacttac     4740

gctatccagt tgcaggtaat tttttgtctg ctagtagtgt tctagattat gtctttccaa     4800

agcgctgagg ctgtgcacct attctgtagt tgcagctgat gcctgaatgt atcctagctg     4860

acaaattatt gattaataag aacttgaatt tctggaagat tcttactgtt aaccaaattt     4920

tgagcaagga gtctcaaagg taattctgaa ccagaattac atgttaatga acagtgtacc     4980

ttttaacagt gtaaatcacg gaatatccgt gaagggattt cttaatttat tttttaccgg     5040

ttgattgaaa tatcagttaa aggttgccag catggttgca gataaactga tgtttgaaat     5100

tcgctgaaat acttaatgtg gaataggata atatacttcc aatgccctca aggctgtgac     5160

cttacagcca ttttacatag cacatcattc ctcctatagg gatgaacttt ttcctggcac     5220

gaaaagtagc cgctctggtt gaagctttgc ttattgtaac aggcttttat ttccaggtaa     5280

tatgtcttgg aagacttaat tctgattaga gatatagata ttactggaaa ctaattgttt     5340

tttttctatt gtactctgct ttatcaaaga agtaaaacat ttaaatcgta ctacagaaat     5400

taagatgttg tcttgcgatc cttaataaat gaatgatttc cctttaatac ggaaaaaaaa     5460

aaaaaaa                                                               5467


<210>  1562
<211>  2965
<212>  DNA
<213>  homo sapiens

<400>  1562
cggggctgta ggtaggagtt aagtgggtag gatcccttaa ccagggttgt ccggtgcagg       60

tggtgtgtgt tgtttcgcct aacgtgtcag tggcacaaat cacgcgaact tcataaacat      120

tgtgcgttcg gaagcctttc caagatgcat ttaatccctg cgtgagccca cgttaggcat      180

tcacgaaggc atgtgcactg ttctctcgga agcggctggc cggcttcccc tcctcgcgcg      240

cggctgtggg tgcaggtcct cacttcccag cctcccatgg gcccaaggcc ttctgggctc      300

caatttgagg cgagccaccc cagatccgta atttttctgc agtgatttat ttttaccttt      360

ctgattcctt gacaaggata tcctagcggc gaaacaacac cgtactggga gtcagaacgt      420

ctgggttcta gtcttgactg ccattaacta gcggtatgac attggagaag cttttttgac      480

ccttctggat ttccgtttcc ttttctgtaa aatgaggagc ttggaagatc cggaaaatga      540

ggcccatagg aaacaagtga cttgctgagt ccagataaca ctgactgtca gaagtctcgc      600

tctgtctccc cggctggagt gcagtggcgt gatcttggct cactgcaacc tctgtctccc      660

gggttcaaga aattctcctg cctcagcctc ccaagtagct gggactacag gcatgtgcca      720

ccacgcccag gagaaacatg aaccagaagc tactgaagtt ggagaacttg ctacgatttc      780

acactattta taggcaactg cacagtctgt gtcaaagaag agcattaaga cagtggaggc      840

atgggttttc atctgcttac cctgtgtgga cagctcaact gtgtgcctgg ccctggccaa      900

cagatgtgct cactggggct gctttatctc agtataggct tctagtaaca aaaaaggaag      960

aaggaccatg gaaatctcag ttatcttcaa caaaatctaa aaaggtggta gaagtatgga     1020

ttggaatgac tattgaggaa ctggccaggg caatggaaaa aaacacagat tatgtatatg     1080

aagctttatt gaacactgat attgacatag attcactgga agcagactca catttagatg     1140

aagtctggat caaagaagtg ataacgaagg cagggatgaa gttaaagtgg agtaaattaa     1200

aacaggacaa agtcagaaaa aataaagatg ctgtaagaag gccccaggca gatccagctt     1260

tattaacccc aaggtcccca gttgttacta taatgggcca tgttgatcac gggaaaacga     1320

cattacttga caaatttcga aaaactcaag tggcagcagt ggaaactgga ggcatcactc     1380

agcacattgg tgcctttctt gtctctctgc cttctgggga aaagataact tttcttgata     1440

ctccaggaca tgctgctttc tcagcaatga gagccagagg tgctcaggtc actgacattg     1500

tcgtattggt tgtagctgca gatgatggag tgatgaaaca aactgtagaa tctattcagc     1560

atgccaaaga tgcacaggtt cctattatcc ttgccgtaaa taaatgtgac aaagctgagg     1620

ctgatcctga gaaagtgaaa aaagagctgc tggcttacga tgtggtatgt gaagattatg     1680

gaggtgatgt tcaagcagtg cctgtctccg cacttacggg cgataatctg atggctttgg     1740

cagaagcaac agttgctctt gcagaaatgt tagaattgaa agcagatccc aatggtccag     1800

tggaaggaac agtaatagag tctttcacag acaaaggaag aggtcttgtt actacagcta     1860

taattcaaag aggaacttta agaaaaggct ctgttctggt tgctggaaaa tgttgggcaa     1920

aagtacgctt aatgtttgat gaaaatggaa aaacaattga tgaggcctat cccagcatgc     1980

cagtgggaat tacaggctgg agagaccttc cttctgcagg agaagaaatt cttgaagtag     2040

aatctgagcc aagggcacgt gaagttgttg actggaggaa atatgaacaa gaacaggaga     2100

aaggtcagga ggatctgaaa ataatagaag aaaagcgaaa ggaacacaaa gaagcacatc     2160

agaaagcccg tgagaagtat ggccatctac tgtggaagaa gagatcaatt ctacggtttt     2220

tagaaagaaa agaacaaata cccttaaagc caaaagagaa aagggaaaga gattcaaatg     2280

tactttctgt gattattaaa ggtgatgttg atggttctgt tgaggccatt ttgaacatta     2340

tagataccta tgatgcttca cacgagtgtg aactagaatt agtacatttt ggagtgggtg     2400

atgtaagtgc aaatgatgtt aaccttgctg aaacatttga tggtgttata tatggcttta     2460

atgtgaatgc aggcaatgtt atccaacagt cagctgcaaa aaaaggagta aaaattaaac     2520

ttcacaaaat aatttaccgt cttgttgaag atttgcaaga ggaactgagc agcagattac     2580

cctgtgctgt ggaagagcac ccagtaggtg aggcatctat actagctacc ttctctgtaa     2640

cagaagggaa gaaaaaagtt cctgtggctg gctgcagagt ccaaaaggga cagttagaaa     2700

aacaaaaaaa atttaaacta acccgtaatg gacatgtaat ttggaagggc tcattaacct     2760

cattgaaaca ccataaagat gacatttcaa ttgtcaaaac gggaatggat tgtggtctca     2820

gtttagatga agacaatatg gaatttcaag tgggagacag aattgtttgt tatgaagaaa     2880

agcaaattca agccaagact tcttgggatc caggatttta aaattacatt aaaaatgtaa     2940

ataactcaaa aaaaaaaaaa aaaaa                                           2965


<210>  1563
<211>  2018
<212>  DNA
<213>  homo sapiens

<400>  1563
gagaggcagg cccatcgcaa ggctgactga tccttcaaag gagcctccca gctaaaagcc       60

agcaggagag agaccttggc caccaagggt ctgccagctc ctggtggtcc ccactccagc      120

cacctgccag ctcgagcctg accctcgcct ccaccctggc tgctgcctgt accgctctca      180

gggctctgcc agcagacagc cttggcacac aggcacaagg gctggagccc agagatgaga      240

gtgcccaagg gagatgtgag cctggcgggc tgcccgctaa cctgtcgctg aagccccaga      300

agcgggccct caggccaggc ctaccctgcc tccggcccag catgcgcctg tcggtgcgga      360

gggtgctgct ggcagccggc tgcgccctgg tcctggtgct ggcggttcag ctgggacagc      420

aggtgctaga gtgccgggcg gtgctggcgg gcctgcggag cccccggggg gccatgcggc      480

ctgagcagga ggagctggtg atggtgggca ccaaccacgt ggaataccgc tatggcaagg      540

ccatgccgct catcttcgtg ggtggcgtgc ctcgcagtgg caccacgttg atgcgcgcca      600

tgctggacgc gcaccccgag gtgcgctgcg gcgaggagac ccgcatcatc ccgcgcgtgc      660

tggccatgcg ccaggcctgg tccaagtctg gccgtgagaa gctgcggctg gatgaggcgg      720

gggtgacgga tgaggtgctg gacgccgcca tgcaggcctt catcctggag gtgattgcca      780

agcacggaga gccggcccgc gtgctctgca acaaggaccc atttacgctc aagtcctcgg      840

tctacctgtc gcgcctgttc cccaactcca agttcctgct gatggtgcgg gacggccggg      900

cctccgtgca ctccatgatc acgcgcaaag tcaccattgc gggctttgac ctcagcagct      960

accgtgactg cctcaccaag tggaacaagg ccatcgaggt gatgtacgcc cagtgcatgg     1020

aggtaggcaa ggagaagtgc ctgcctgtgt actacgagca gctggtgctg caccccaggc     1080

gctcactcaa gctcatcctc gacttcctcg gcatcgcctg gagcgacgct gtcctccacc     1140

atgaagacct cattggcaag cccggtggtg tctccctgtc caagatcgag cggtccacgg     1200

accaggtcat caagcctgtt aacctggaag cgctctccaa gtggactggc cacatccctg     1260

gggatgtggt gcgggacatg gcccagatcg cccccatgct ggctcagctc ggctatgacc     1320

cttatgcaaa cccccccaac tatggcaacc ctgacccctt cgtcatcaac aacacacagc     1380

gggtcttgaa aggggactat aaaacaccag ccaatctgaa aggatatttt caggtgaacc     1440

agaacagcac ctcctcccac ttaggaagct cgtgatttcc agatctccgc aaatgacttc     1500

attgccaaga agagaagaaa atgcatttaa gtggaaatcg gacctctaat ccaagcatat     1560

tgcttgctat taatcgccaa aacaggactg ctgatgagga atgtatttgc atatgtttgc     1620

aaaagctgaa tcattgaaaa cgtaccttga aactctctat ctctggacac tccagggtag     1680

agaatgaagg gtatggaagt agtccggctt ttgaaactta ggtattttat atttttcccc     1740

tcaagaactt ttttttaaga gacagatttg ccatcctcct taatttgcag gactgccttg     1800

gtggctttgt ttgctgggac aaggcccaca acctgtgcct ctcctattga cccttacttt     1860

gaattcaaag aatctattta agagtttaat atatgaggct ttctttgatt cctcctcagt     1920

tctacctagt ttcacagagg aaaaaaatac tctttgaata aagtgaacag aggctcattt     1980

gtttgtgcct tactttactg aaaaaaaaaa aaaaaaaa                             2018


<210>  1564
<211>  7259
<212>  DNA
<213>  homo sapiens

<400>  1564
cactagaatg tgaaggatct tcgcggttct gggtgcccag aaaggcggcg acgcggcgga       60

tgacaacatt aggccgcgac gcgctcctgg ccaggcggcg gctgtagtgt tagctttgga      120

cgccgcagta gccgctgccg gtagcaagcc gactgaggga aggtgggggt ccgcccgggc      180

tggtggacct cggggccgaa agttcccgcc ccgctcgggg gctgagccgg cagtgcctcc      240

gcggccgctg ggcagcgccc ttcgtccagg ctcgcgcccc agctgccgcc gacgacagcg      300

gccgagagaa gttggggtct gactagacgc ttacggggcc tcggaccccg gcgccgcggc      360

gacctcggag gaaccggctc cttgcgtccc gcctccctgg gagctccgca cgggatttgc      420

agatttacag aatggctgca cattaatgga aagagaagca taaacctatc ttctttcatt      480

atggagggag gtttggcaga tggagaacct gatcgaactt cgcttcttgg tgatagcaaa      540

gatgtccttg ggccatcaac tgttgtagca aacagtgacg aatctcagct tctgacacca      600

ggaaagatga gtcagcgcca aggaaaagaa gcttatccaa cgccaaccaa agatttgcat      660

cagccatctc ttagtccagc aagtcctcat agccagggtt ttgaaagagg gaaggaagat      720

atttctcaaa ataaagatga atcttcactt tctatgtcaa agagcaagtc tgaatctaaa      780

ctttataatg gctcagagaa ggacagttca acttcaagca aactcacaaa aaaagaatct      840

cttaaggtac aaaagaaaaa ttaccgagaa gaaaagaaaa gagccacaaa ggagctgctc      900

agtacaatca cagatccttc tgttattgtt atggctgatt ggttaaagat tcgtggtact      960

ctaaagagct ggaccaagtt atggtgtgtg ttgaaacctg gggtgctact gatctataaa     1020

acccaaaaaa atggtcagtg ggtaggaaca gttcttctga atgcctgtga aatcattgaa     1080

cgtccatcaa aaaaggatgg cttttgtttc aaacttttcc atcctttgga gcaatctatt     1140

tgggcagtga agggtccaaa aggtgaagcg gttggatcca ttactcaacc cttacctagc     1200

agttatttga tcatccgagc tacttcagag tcagatggaa ggtgctggat ggatgctttg     1260

gagttggctt tgaaatgttc tagtcttctt aaacgtacaa tgatcagaga aggaaaggaa     1320

catgacctga gcgtttcatc agatagcaca catgtgactt tctatggctt actacgtgct     1380

aacaatctcc acagtggtga taacttccag ttaaatgata gtgaaattga acgacaacat     1440

tttaaggacc aagatatgta ttctgataaa tctgataaag aaaatgatca agaacatgat     1500

gagtctgata atgaggtgat ggggaaaagt gaagaaagtg acacagatac atcagaaaga     1560

caagatgact catatatcga acctgagcct gttgagcctt taaaggagac tacctacact     1620

gaacagagcc atgaagaact tggagaggca ggtgaggctt ctcaaacaga aactgtatct     1680

gaagaaaaca aaagccttat ctggacacta ttgaaacaag tccgtcctgg catggaccta     1740

tccaaggtgg ttctgcctac atttattttg gaaccccgtt ctttcctgga taaactttca     1800

gattactact atcatgcaga tttcctatct gaggcagctc ttgaagaaaa tccttatttc     1860

cgtttgaaga aagtagtgaa atggtatttg tcaggattct ataaaaagcc aaagggactg     1920

aagaaacctt ataatcctat acttggcgag actttccgtt gtttatggat tcatcccaga     1980

acaaacagca aaacttttta tattgctgaa caggtgtccc atcatccacc aatatctgcc     2040

ttttatgtta gtaatcgaaa agatggattt tgccttagcg gtagtatcct ggctaagtct     2100

aagttttatg gaaactcatt atctgcaata ttagagggag aagcacggtt aactttcttg     2160

aatagaggtg aagattatgt aatgacaatg ccatacgctc attgtaaagg aattctttat     2220

ggtacaatga cactggagct tggtggaaca gtcaatatta catgtcaaaa aactggatac     2280

agtgcaatac ttgaatttaa actaaagcca ttcctaggga gtagtgactg tgttaatcaa     2340

atatcaggga aacttaaact gggaaaagaa gtcctagcta ctttggaagg tcattgggat     2400

agtgaagttt ttattactga taaaaagact gataattcag aggttttctg gaatccaaca     2460

cctgacatta agcaatggag attaataagg cacactgtaa aatttgaaga acagggagat     2520

tttgaatcag agaaactctg gcaacgggta actcgagcca taaatgccaa agaccaaact     2580

gaagctaccc aagagaagta tgttttggaa gaagctcaaa gacaagctgc cagggatcgg     2640

aaaacaaaaa atgaagagtg gtcttgcaaa ttatttgaac ttgatccact cacaggagaa     2700

tggcattaca agtttgcaga tacccgacca tgggacccac ttaatgatat gatacagttt     2760

gaaaaagatg gtgttattca gaccaaagtg aaacatcgta ctccaatggt tagcgtcccc     2820

aaaatgaaac ataagccaac caggcaacag aagaaagtag caaaaggcta ttcctcccca     2880

gaacctgaca ttcaagactc ctctggaagt gaagctcaat cagtaaaacc aagtacaaga     2940

agaaagaaag gaatagaact gggagacatt cagagttcca tcgaatctat aaaacaaaca     3000

caggaagaaa ttaaaagaaa tattatggct cttcgaaatc atttagtttc aagcacaccg     3060

gccacggatt attttctgca acaaaaagac tacttcatca ttttcctcct gattttgctt     3120

caagtcataa taaacttcat gttcaagtag aagttctcta ccattgaatc agtgaactag     3180

aaagatctga tttggcctgg gaccagtgtt caagttggtt tggtctttat taaaaatcac     3240

aatattccga aaacaaaaaa acctaggaga taaatgtaga ggtattgact tttcgtatct     3300

tttatcttca cactgaaaca agagctatcc tatttgatta ttaaagtgag ctatgtgtta     3360

agtgccagga catttctagc ttttgtgaga atgtgtctac atatgagtat aataaaccca     3420

catgtataca caattgtctc ttatgtactc ctacctgaca gtagtctttg tattctatag     3480

tatgttctga gatataatgt taacattgtt cataacaaaa aatgctatca atcttataaa     3540

tatatgtaat ctattttctt cataaaacag gcacaaaagt tttatcagta aggaattaca     3600

gattgagaaa tgatggaata atagacataa ttaattcaat acactactgt taaaatcatt     3660

tgcaaagcac tcagctcaat tatcttctta gaaagaaaga aaaagtatga atggtcaaaa     3720

tgaatacatc gagagagata aatggcaaat tgctttttta aaagtttaca taagtttttt     3780

ttaaccccta gaatttaata tttgtagatg caggtaaata tatatactta cgtgtatatc     3840

agtataaaaa cactggtgtg caattaattg gattgattat aataccacct taagcacttg     3900

ctgaaaaaag tgtggtcaaa attgattgct gtccttttgt cttatttttg tttttcttaa     3960

gtcagctggt tcataacata ggccaaattc tagagatgtt tatagagcat ttgaagtgct     4020

gataatttat gttttttcat tatgaaaact tattttagct ttagactcca gtgtgttcag     4080

tgaataagta gaatataaaa aaatataacc agtattttac ttcaaaagcc aaaaagaggc     4140

aataagaaaa gacactttgt ggtggccttt atgtgtgcat taaaattggt ttctgtaaaa     4200

cgtgtaataa gttgagtatc tacgaagagt atcaagttct gaagtttaat ttttttatta     4260

tcctcctctc ttcttagtaa cttctttctg tggcaaaacc acaattcttt aagattccta     4320

ttgttcaggc taaggcaaat ttttttgttt gtttcttcag tttaatattt tgattttgtg     4380

tttttacgta aatatttata ttccttgaaa gcaatttttg ccaaggtagt tcagtttagg     4440

aatatgttgt tctaaaatat gtcttagaat cctgaaagca tagattttga aatgtttttt     4500

taatgaaaat gaaggtcaga gagaataatt gccctgacca catttgcctt tcagtaggag     4560

gaggctgtga aatagtaaaa ttataatcgt ttatgccatg ataaatacaa gattggtaaa     4620

taaatacatt gattggtaaa ttatgagaat caaaatgata aaaagagcct gcttttttcc     4680

ctaaccaata tagctatctt aagtatcctt aggtttctgt gaagaaccat ttcccatgtt     4740

ttcttggcaa aataatgctg tattccatat gtacatgtga aatgatgttt taaattgata     4800

aaagcttaaa taagatctac ctatacccag tattttcatg atattagaac aaatgggttt     4860

ttggttatat tttatatttg tcaatataat ttttgtattc acattctgtt acactctgcc     4920

tattcattga tatatgatat tctgtaaata ttgtacaatt tgatcttttt tatggtttaa     4980

attagttaat tacatacaaa ttgattggct tatcacaaaa atcatttcat cagtaaacct     5040

tgttaacatt ttgtactggt gacccacctc ttaggacttt ggtcttatcc acgtgtatgt     5100

tgttttcatt tggtccaaat aatattttat ttgtatgggt atcttctaag actaaatagg     5160

tagttgtgtt ctttattttt aaaatttctt tttagagcaa atgttatggg ttcttaccca     5220

aagagtcaaa aactatttct taagaaagag cagagttatt catgactgtt ctttatacac     5280

taaaagcatg catctaatct aatagtcctc ttattatgct tttagttgta tgagtctctt     5340

tctatgaact gaacacaaaa ctcaggaatt ggtggcttaa ttttagatca gtgcttgtac     5400

taggcttagt tatatgaatc tttataacac ataattacta actttgtagc catatatgta     5460

attgactttg aatgttattt acctgaaatt aatcttcctt cacacatgga ccgtaaacgg     5520

ttcccagttg tctgagagcc tcatgagggt ttctaggatt tatgacctta tgaccagttt     5580

ttttcattta ccaagatttt attttcctac atgaaaattt aattgagtaa taattattca     5640

catgtgcatt ttctttttag ctgttaaatg tactatgcca tcatccacca tttagtaaaa     5700

tgtagctggc ccaggacatg taaaaaaaaa aaaaaaacaa caacaataaa tagggcatgt     5760

gaaatgttaa gttacagcaa tagatatttt atttgtattt catgttagta cttttttgtt     5820

ttatatcact tataaaggta cagtgtactc tttgtcacag ctcagttggt aaccgcattc     5880

cattgaaaag ttggccttgt aaaatacaac tctcatttaa tattcatgct tttgtgcctt     5940

taagaaaata ttttttgtca ttttttgtgt tacagaacta taatgtgatt caaggtgttt     6000

ataggcttgt cataaaaggg tcatttctgt gtgttacttt ctttttatat agctatagta     6060

tatttaaaca ataatactat cttttatagg ggtttgtcta tttacctatt ctttactcag     6120

acattgatgt agacttgtca gattattctg agtattgtta acagtgcctt ttcgatggaa     6180

tcacactttt tggctgtcac cttgtgccat atacacacaa aattttgtgg aaggcagttt     6240

taactttctg aagaatatct gtcaaaattt aagaaaacaa atgtataaaa ttccattttt     6300

tccagtgttt agcatttcta gtaagcagtg aggttgtttg acatacagtg atgatggcat     6360

tattgataag ccatacatga gactgcagat tatattgaat catattaaat gtacagaaat     6420

aaaatattag atttatatca aattttccaa tttgaaccag tggggaaaat cccacagaaa     6480

tcagtaagtt tacatttcaa tttctatctt atttgactaa gtggaaagag attctttaaa     6540

atgtataacc tgccattatg taatttggtt tcattttatt ctacctgttg tgtgagttta     6600

gtatatttaa tttacttttt gttactcttt acatactgtt tatttttgtt agtttttaat     6660

tgaagatgga ctgttgaaat tgtataggac cagtgtctta ttaatatgat taatatattt     6720

agaagagcca cgtgaaaccc atgacaaaat gaatgtgaat attctttcta aaaatttaga     6780

aaatgttatc tttttgcatt tattatgtaa aactgtttta cagtatcaaa atttttcact     6840

taaagaaaaa aaatgccatg aaacatttga actgatgagc cacagaactt cagttgaaat     6900

ttttttcact ttttagcatg ctaaatatac atctgagttt aaatgttctg tttaatggcc     6960

attcataaat tcaagcacta ccactggtca gttttgtgtg atagaataaa aatatgttac     7020

ctgcagtgta agtacagcac actgtcaaat tcttttcctt aaggtgcaca gtaaatgtac     7080

agatagttat aggccactgt tttgtaatgt agtacatttc taatctatta ttcctaacct     7140

attataactg tttgcagaaa gaaaagaatt tttctaataa tctgtaaaat tatgctaact     7200

tctacaagta ggcttctaaa taaaattttt aaaaagagca aaaaaaaaaa aaaaaaaaa      7259


<210>  1565
<211>  8485
<212>  DNA
<213>  homo sapiens

<400>  1565
aacattcgcc ctcctcctac cagcgcgcgg gcggcggcgg cggcggcacc ggggtcacga       60

actctgacct ttcactgaca aaaacaataa caaacccccc cttctccgcg accccggcgg      120

cgcccccggg cccgtccccg ccaccccgct cccacctcgg cgtctcgtct ctcgcccgct      180

gccccgcgag cccgcggccc ccgggctccc gccatccgcc gacaccggga gcccgggctc      240

cccgcgccct gccctccgcg ccgggggccg cccgccgcag acacgggacc cgcttcgagg      300

ccgctttggc gccaaatcct gaggtaacac gtacacagac ctctcggccg gaatctccag      360

ggatgaccag cccctcccca cgcatccaga taatctccac cgactctgct gtagcctcac      420

ctcagcgcat tcagggctct gaacctgcct ctggcccatt gagtgttttc acatctttga      480

acaaagagaa gattgtcaca gaccagcaga caggacagaa aatccagata gtcaccgcag      540

tggacgcctc cggatccccc aaacagcagt tcatcctgac cagcccagat ggagctggaa      600

ctgggaaggt gatcctggct tccccagaga catccagcgc caagcaactc atattcacca      660

cctcagacaa cctcgtccct ggcaggatcc agattgtcac ggattctgcc tctgtggagc      720

gtttactggg gaagacggac gtccagcggc cccaggtggt agagtactgt gtggtctgtg      780

gcgacaaagc ctccggccgt cactatgggg ctgtcagttg tgaaggttgc aaaggtttct      840

tcaaaaggag tgtgaggaaa aatttgacct acagctgccg gagcaaccaa gactgcatca      900

tcaataaaca tcaccggaac cgctgtcagt tttgccggct gaaaaaatgc ttagagatgg      960

gcatgaaaat ggaatctgtg cagagtgaac ggaagccctt cgatgtgcaa cgggagaaac     1020

caagcaattg tgctgcttca actgagaaaa tctatatccg gaaagacctg agaagtcccc     1080

tgatagctac tcccacgttt gtggcagaca aagatggagc aagacaaaca ggtcttcttg     1140

atccagggat gcttgtgaac atccagcagc ctttgatacg tgaggatggt acagttctcc     1200

tggccacgga ttctaaggct gaaacaagcc agggagctct gggcacactg gcaaatgtag     1260

tgacctccct tgccaaccta agtgaatctt tgaacaacgg tgacacttca gaaatccagc     1320

cagaggacca gtctgcaagt gagataactc gggcatttga taccttagct aaagcactta     1380

ataccacaga cagctcctct tctccaagct tggcagatgg gatagacacc agtggaggag     1440

ggagcatcca cgtcatcagc agagaccagt cgacacccat cattgaggtt gaaggccccc     1500

tcctttcaga cacacacgtc acatttaagc taacaatgcc cagtccaatg ccagagtacc     1560

tcaacgtgca ctacatctgt gagtctgcat cccgtctgct tttcctctca atgcactggg     1620

ctcggtcaat cccagccttt caggcacttg ggcaggactg caacaccagc cttgtgcggg     1680

cctgctggaa tgagctcttc accctcggcc tggcccagtg tgcccaggtc atgagtctct     1740

ccaccatcct ggctgccatt gtcaaccacc tgcagaacag catccaggaa gataaacttt     1800

ctggtgaccg gataaagcaa gtcatggagc acatctggaa gctgcaggag ttctgtaaca     1860

gcatggcgaa gctggatata gatggctatg agtatgcata ccttaaagct atagttctct     1920

ttagccccga tcatccaggt ttgaccagca caagccagat tgaaaaattc caagaaaagg     1980

cacagatgga gttgcaggac tatgttcaga aaacctactc agaagacacc taccgattgg     2040

cccggatcct cgttcgcctg ccggcactca ggctgatgag ctccaacata acagaagaac     2100

ttttttttac tggtctcatt ggcaatgttt cgatagacag cataatcccc tacatcctca     2160

agatggagac agcagagtat aatggccaga tcaccggagc cagtctatag cgcaaaccac     2220

acacctgcca aggagcaaca gaatccttcc aggaccgttc acatacaaag aaaagtagtg     2280

gtattttggt atgtgcaaat atttccatat gttagccatt tcctgtctgg tttctcctta     2340

tctgttaatc ccagacaata gcaattaaaa gactagtagg atcctttcct gacataagaa     2400

atgttttaat gccttttgat gaagcagcag attttggaac aatcttttaa ctcaatttgt     2460

atttagaaat tctcaaaggg caaaaaacaa aaaaaaaggt tttataatgt cagagactag     2520

tattaaagaa aactgaaaga acctgagaga atagtatgtg tgtatatata tatataaaaa     2580

agtccttgga attatagata ctaattacca gggtaataat attagcactt tctaagcact     2640

tatcaatgtg taacgttagc aacatcttgc ctgtgggcag ggcaaatgga aaactgtgta     2700

tgtcttttgc cgaaatgcta atgatttctg tgaaaactca ctagggtaca ggagacaatc     2760

atttatgttt aagaaaagaa ggcatcattc ctaattgtgt gcacatgttg tggagttgag     2820

ctgaattctg tgaatggaaa cgtggctcat ttgcatcatg cagtaagtgg gagtgtggta     2880

gcacagtcgg tggtgaccca gttcagaagc ttctagccat agagcagaca cttgtcaggt     2940

tccctgacta cttggtcctg gtctctgatg ggcatctgca gactcctcta gaacctgggg     3000

ttctcctttg atgactggtt atctgaattg gattgcaact agtcagacat taactgccaa     3060

atgagatgta cagttcctcc agcaagtgaa aacatcccca agtcacatcc gccgctcgtg     3120

gcagatggag ccttgtgacc aaaaagtgca aggtgggcat tttgagctct tgacagtact     3180

tccaatacaa ttgggggtgc ttgtgtgttt gtccagatgg aggagtgtgg ccttggagtg     3240

tgagcgttac cttcccaggg ctttccactc caaatgcccc cttgaaaagg gctcgtgttt     3300

ctgcagctcc atcataactg tgaggctgga ttggggctgg gcaggagcct gctgccgcct     3360

ggcgagagtg gttagggcct ggtaaagctg gatggaaggt ttcaggacaa tttcttcctg     3420

ttgaccttaa ataccagaga ttttaaaaat gtgtatagac tcagcatctc tgttggcaag     3480

tctgttaatg ttaccagcac actgtgcact ttggttcccc caggtgtgtg ccagccgacc     3540

accccggagc attttaaatg caggctgctt gctccttaaa aacaaccctc aatttccagg     3600

gtgatagtct ttctcctcat aaattgtagc aaccagagtt tacagcaaga acagtatgcg     3660

cttaaaagga agttatgtct aacttcaaac acccgtaaat tcccacggat gtgaatatat     3720

agcaagcttt tcctgtttga gaacagtggc atgtggaaga cccggtcaat tgctttgtct     3780

tttgcttttt aaatagtcca gattaagaaa atacaccctg ttgggttaaa tttgcctctc     3840

ttgatttgtt aatcagatga tatccaaaaa gatccctgga cactcccctg actcacaggt     3900

gctctgatct ggctcaggct ggcgccacat gtgctccaca ggggtgcagt ctggccagct     3960

acagacgccc ctgtggtgcc acattggaca gaatggaagc tgctgcaggc tcaaggcaga     4020

acaggatgct tgatcctgaa gggttagcag cactttacgc aagtcagtgt tagtagggta     4080

agtgggaaca gtgtttccaa cttctaaatt cttgtttgga tttaattata tcattttata     4140

attcttgcct tggcagcaaa ttttggagag tagtgggagt ggccattata aaatgatgga     4200

aaggatttaa ttttgccagc ttaaagtaat ttttactttt ctaaccctga tgtgttttca     4260

gtttcaaaat taagacaaaa aaccagctga gacaatggaa ttagggcagg tttgtttcat     4320

ttctgcttgt gaaggctttt agtagcaggc atcctgcagc tcagtggtgc ctctaacaca     4380

gattgttgcc tgccttccgt cgttttgatc cttgagagtg accatgaggg ccatgttgca     4440

gttccctggg aatacaagca taacagcttt cagatcccag ttcttggtgt tggtgaaaag     4500

gtctccacca gcccctcctc tcattcccag gtcattcagt ggcagccagt aggctgctta     4560

gactcaggct ggataaggaa gtgttgggct gtggtgaaac aaccttgcag aaaacgtgat     4620

tttgcttgga aaggtgctga ttctaacctg gtcctgctct ttaagtcccc ttgctggtga     4680

tggctgattc cagggactgt tttgggcttt gaacacctct tggttggttt ctgagatcct     4740

cttggcctta ctttgaagtg gccttttctt taaggatcat gtccacgtaa cctgtattct     4800

tgctgcttta actcatttca agcctctgac tgcaggtcca tttcatctcc tgtcaggttg     4860

gttaagtaaa gtcagcccaa agtcaagaat tacttaaaga gatgcaaacc aaatatttgg     4920

gctccaactt tcacagggct tatagccctt attagcagtt tgtgaaactt tgggtttcat     4980

gaagtgagac ctgtcctctg gctactgaac tccatggagc cacgttcatg ctccctcttc     5040

tactggcctg gctgctcctc cctcaatgag gagaggcagc tggctcagag aggtgggaca     5100

gacacatgct gtcatcagtt aagtgagctc ttttccagaa gtatctcaga taatgttggg     5160

ttaagacaga tagatgttga aaatggtgga gatcattaca cattagcata aaacaggaca     5220

ggaagagatt ttttgaaaga ccaaattagt tgagcaagta atacttttca agttactcct     5280

ggaaggtgtt tttaaggaag tgtgttacct accatactct cctaatttga catttctgtg     5340

tcctgaggag ttacatttat tgtctaaccc ttgccataag gctgtggttt gaggttcttt     5400

tgctgttctg ggctttatat ttaatttcag gtgtagtcac ttctaagatg tgtaattgcc     5460

ctcaagaggg actgattttt agcttgtcat tgtcagtatt gaatgtggac tcttctgagg     5520

cagttaggac accagccatg gtgttaacag tggatgcgtt aggctcctta atctcaaggc     5580

aatatccacg ctacacacat acttattagc tgtcttactt gtttggggga tagttacggc     5640

aaggagcaaa aaattctaag gactctagct gtttctagtg cttttacttt catagtcctt     5700

tgaggacatt tcctgcagag cactcttgct cacagcccgc cctctgcagg gcttccagcc     5760

cctggccgca atcagcagtt catgccacat gtgtacatcc atgttctggg acctgatctc     5820

attggagtcc agaagcttgt tgcccacttt ccagtgtaaa tgactttatg tgcaatgggg     5880

tcataggtaa cattttaact cttttcttag tccaggtcat aggaagtctc atcatctgac     5940

agccactttt ctcccaggga aggcggtgcc cactgggccc tgggaatgcc tgagccagca     6000

gagcagatgc cccacgtgct tcctttatcc agcttccatt ctctcagtta tgaggctctt     6060

tgaaaatgtc ttaactttga tgtaaatttt taaagccaac ccctcatcaa gacagggttg     6120

gtttgggtct tttgtacaca gggtctggac cttctcattg tgtgcctccc accagcgtgc     6180

acttcgtatg tccagccctg ggtcccttca gcagcattgt gcgtgtacag gtttctaggc     6240

tgtaagactg aatgaatgta catgtgttta tatcctctcc atatgtacag tgtatatagt     6300

gtgtgtatgt gtacatagat gtatattatg tatacagaca tgtatccaaa ctttccttta     6360

aagagagttt ttcataaagt tgctaatgta aactgatatg ggtgttccaa ggtccctcgg     6420

cagggaagat ttgctggtga ttttcttcac tccattttcc tttgggtgag cctgcctggg     6480

aagggccatg aagtcagaat ctccactctg caaaaggaag aattccaggc agaagaggtt     6540

ctgacagggt gacatttccg tatattctct aggttcggac aagagccagg aagctggaag     6600

acagtttatc ttaatatcca aaactaagtg ggaattttta accttttcat gcacctattc     6660

atggccctac ctggaaggaa cttggcagtt gggttgagcc atcagccttc ccagctattc     6720

agctctgttg agtagcccag agacaggcgt cacggtcaga gattcagaac ggtctgtgtc     6780

agtgaggcct gactcccaaa gatggtagca atttcccagg cttgcgctgt gctcagtcag     6840

caagatgtgg ggcactgtcc tatgactgaa taaatagtaa ttcccatctt tctatcgcca     6900

gttaaaaata aacaacctac caagtattat tctttaaaac taagcatgga tgttgatggc     6960

taacttctgc ggcatataag ctacagatct caagttactt ctctaactgt aagcatgtaa     7020

atgactttaa ctcctttcta taagttatga ttttaaattt tcagataaga attgcatttt     7080

aatatggata tgtgtgccct taaaagctac agataccaaa ttttcctcgt ccaggtctac     7140

tcggacgaat tttccccctt aatctggcct taaactgaga ctcggccctt gagagccagg     7200

gcctggccca gcagtagttg ctcatagacc tgggaagcag gggcctgctg gaaggaatca     7260

ctagattgct gcaaaaactc acataatcca cagtttcctc tttttctttt taaaataagt     7320

tatcaaaatg ttttaaaaac actttatgag accatagtac tcagtgcctt ttgtgagaca     7380

gtgggtcatt tagccttcag cttccctgtt tttgatgtag agaaagcttc tatttcactg     7440

gcctcatccc acaagattgt gcgacctttc cccgtcatag cctgtcgtga caatcacgct     7500

attgaaagtg gctttctagt taaaatgcaa ttggaaactt gacagtctct aaatgaatta     7560

aaagtttcct ttggggctat ttagcttaac agcagtctac aaataattaa agtgtgagct     7620

taagaaaagt atctttgcgg ggagaaaaat gtcagatatt tttaatgccc agctataaat     7680

aattttggtg tcttgatatt tatacatgca aaatagaaaa aaaatgttca acatttattg     7740

attgatagac tgttaaaatt taatgtttgg aataacattt ggaagtagta gactttgcat     7800

taaaaaatgg cttttcttta ggaaagtata atcaattatt ttaatgacca tagcattcat     7860

ggactcaaat gctgctgcca cacacaactc aagtgctgga atatttttct acagtctctc     7920

tgttctacgg attatcttgt aaaccagtgt tcaactagtt ttataactga aaagctgcac     7980

atttttcaca gtacaagccg tagtttttac ctgtagtttg gacttctctg ttagaatgta     8040

actgcattac cagccctttt aaaggcatct atctatcaaa ggaaaatttg ggtgttagat     8100

tttcttggga ccgtttctgt aacctttgcc cttcacaata tagaaaatat tggttttgcc     8160

attacatttt aatgccaggt ttaaaacctg ttgaaagctg cagctttata cagctttctt     8220

ctccctgtga aatcactttg tttatgtgat ggcatttaaa aaatagcatg ttctttttaa     8280

actgaatttt atatctaatc aatgtcttca gtcttgaaga agaatttgca ttgttgtgtt     8340

tgtatataga gtattgcagt gcatgaatta gctttatgca ttttattaaa tgctgtttca     8400

atgtggcatt attgttgtgg cttaatacta ctacctaaat gaggtttata ctattaaaag     8460

tgaattaaag actaacatgc aaaaa                                           8485


<210>  1566
<211>  6300
<212>  DNA
<213>  homo sapiens

<400>  1566
gaccaggact gtgcggctgc cggagtcctg ggaagttgtg gctgtcgaga atgggggtct       60

gtgggtacct gttcctgccc tggaagtgcc tcgtggtcgt gtctctcagg ctgctgttcc      120

ttgtacccac aggagtgccc gtgcgcagcg gagatgccac cttccccaaa gctatggaca      180

acgtgacggt ccggcagggg gagagcgcca ccctcaggtg taccatagat gaccgggtaa      240

cccgggtggc ctggctaaac cgcagcacca tcctctacgc tgggaatgac aagtggtcca      300

tagaccctcg tgtgatcatc ctggtcaata caccaaccca gtacagcatc atgatccaaa      360

atgtggatgt gtatgacgaa ggtccgtaca cctgctctgt gcagacagac aatcatccca      420

aaacgtcccg ggttcaccta atagtgcaag ttcctcctca gatcatgaat atctcctcag      480

acatcactgt gaatgaggga agcagtgtga ccctgctgtg tcttgctatt ggcagaccag      540

agccaactgt gacatggaga cacctgtcag tcaaggaagg ccagggcttt gtaagtgagg      600

atgagtacct ggagatctct gacatcaagc gagaccagtc cggggagtac gaatgcagcg      660

cgttgaacga tgtcgctgcg cccgatgtgc ggaaagtaaa aatcactgta aactatcctc      720

cctatatctc aaaagccaag aacactggtg tttcagtcgg tcagaagggc atcctgagct      780

gtgaagcctc tgcagtcccc atggctgaat tccagtggtt caaggaagaa accaggttag      840

ccactggtct ggatggaatg aggattgaaa acaaaggccg catgtccact ctgactttct      900

tcaatgtttc agaaaaggat tatgggaact atacttgtgt ggccacgaac aagcttggga      960

acaccaatgc cagcatcaca ttgtatgggc ctggagcagt cattgatggt gtaaactcgg     1020

cctccagagc actggcttgt ctctggctat cagggaccct cttagcccac ttcttcatca     1080

agttttgata agaaatccta ggtcctctga gcaacgcctg cttctccata tcacagactt     1140

taatctacac tgcggagagc aaaccagctt gggcttcttt ttgttttttt ctgttattct     1200

agatttgttt tctttttgtt tttgtttatt tgtttgtttg cttttatttc cagcttgaat     1260

gagtggggtt gggggcgggg tgggcagggt tctaccacgt gtaggataat cattcattgg     1320

tgtgtccaaa aatggggtct gctcctgcta ccttgaccct tccctttcct ctgcttctct     1380

cctcatcatc attcccaaca acatcctctg ccacacacaa caaaacgtaa gtttcatttg     1440

ggcaaaaatt gagcctcaca ataaacaccc tgaagacaca acttgactta taacatagtg     1500

cacagcaaga gctacatcca agtgtcctat tatctgtgat tattttctta atgacaatgt     1560

acatatgccc ccatccatgt taattattat ctaattccat tagggttcac gtcttttctt     1620

tctgggacac tatcctacta tatccatatc tatagatttc aatatagatg attgtgccat     1680

cttctgtagc ccctccgctc tactcattcc ttccaccatc tgcagagatt tgaagtttgg     1740

ggctatgcat gaaacccaac actaaatttt gcaagtcaag taaccaaaaa agggggaggc     1800

attttgaaga tagaacctct attttaaaaa gagaagttca actcataaac gtgattgata     1860

ggtggctgat ttatttaggt tttgtcaagc tatctatcaa agtaatggta cagttaccca     1920

tctactcaaa tatctgattt atctcaccat ccaattatct acccacctgt cttcctctct     1980

agcaatctat ttactgttta tcaatctatc aatgtaattg tctaacactc ctttctattc     2040

tctccctact actcactatc aattcatccc catatgaatc tctaaccata ttgtatctct     2100

cccactgtat tcatttatac accatcagca gacattggca tcttcaaaat tatctttcaa     2160

cttctgtgaa agccaacgat ctcacaggtt aacaaaatac aaaagcaata ccctgtgttg     2220

tggactcttt aaaatctggt atcctatcca cccaagggag acactaacag ataggccaaa     2280

gtagcaagct aatgatcagt cactcactat tcccagaaga gcctgtgttt tctaaaacac     2340

tttcttggga agcagatcag cctagaaaag ttttgattag cactgtggtt ttccttttgc     2400

acttgaagga caaaggtgcc agcctttatg cttctctcaa cccttcaaga aagtacatgt     2460

caggaaccta tggctggctt tccttagcag caagaacttg agagaaaaac acatctgtct     2520

ctgcaatgca aagtgaagag tccacccgcc tgagtgggat gacttcagct agagtctcct     2580

ttctgctcca gttctggttt aatctgtttg aaaactatcc agtaaaaagc tgatggaggc     2640

caattacatg gcgggtgtat tgacaactct ggtatttgtt tcaggaagct cttctaagct     2700

gagggcactt gagcaactga cttaattttc aagcacttga ttaacacaac actgcaaaca     2760

gaagggagaa agtgtcagtg acacagtttc ctctgatgca gctgcttctc caatggcttt     2820

ggggaagaac ttcaccagct cttcaggttc aaagcagacc cagcatacaa acaagagctg     2880

agccaccttt gctgtcttgt ctcctgggac gagaaggact catccagcaa agttgcctgg     2940

gattcaaaat aaaggcattg cagaccgcac aggtgtgctg cagggactga tccacagaga     3000

ggatgagaat gcagcatcaa tcgcagacct gccctgcctc agttggaaaa ccttttcagg     3060

ccctcagtct aaaaaataaa aaatatgagc accattgaat tctgtgccct taatgcttaa     3120

ctggtcttct tcctctggta tcagtgtcct ctttgttttt gtccatcaag gcacatgagt     3180

gtgacctctg ccatggggaa acacacacag agatatctat acatatatac atacatacaa     3240

acataggcta tcttggcaca ctaaatgcta agcactgtct taagaggtag agctggtgtg     3300

agtgaaatta atgttacatt ttccagctgt aaacagacat ctgcatttcc tagtgagctg     3360

ccaggagcca gattcgggaa ccgtaactga tgtgccagga atggtgcatt gattcccagt     3420

tccagggatg atcatgagca ggcgcaaaat cagaattaaa ggtcgcacat agacgtttca     3480

gatctgtcac caccttcagc atctggagtt gagttggtgt cagatagtgt atgagaatta     3540

aatgtgtcat ctgagcatgc tactgatgat aaatttgtta ctttggagtt gaataaatgt     3600

gaaggctgtg aagagtggac agtcttggag aacacagtgc ttgaaatgga caagctggac     3660

ctattcctca ctccaagact tgttctacag gaaagggtcc atgctccttt ggccaagatc     3720

atcagaacct ctcaacccaa caaggctggc ttcagggcca ctatggaacc ctgctgttcc     3780

cccttccaaa ggatactaag atgcccctct ggtgggtacc tatcccagcc acgtttcaga     3840

gggagagaaa tgctacagtt gatcctcatc tgtctggggt aaagacaaca aagtaaatac     3900

aacccaaggc aactggggta ctcactggga gtgaaaatga cttcttcaca acagacatat     3960

ttctgcttct gtgtttttgt gtttctttgg tggggatggc ttcatgggag agtggctgtc     4020

acccatcatt ttgaagcata tagaacaaca aatgcttaca caagacaata tccacacttt     4080

tccaacttca cacacggaga gtacatggag aatgcctaca ggctagattt gttcagggtg     4140

ccagtagtgg gcatggggtg ggggcaaggc aggacaaaac atacaagtct gagcaagtac     4200

atctcttgca ggttttccac atgaaaagga agccaaataa gtcctgttag gagattaggt     4260

gagaggaatt agcaatgtag ggactctgaa acccttcccc ttcccaaaac agagttcata     4320

tgcacttcca ccaaagtaat gccaatgaaa gtgctcgtgt taaggctgca gccaagcttg     4380

tttttcagta gtttaatgtc aagtgcctga tacagtcgac tgcaagtcta aacaagcatg     4440

tttagttttt ctcattcttg ctttaattca gggaggggga gatgtagaga agtggttgtg     4500

aaaacatgta caggctttat gcagagcact gcgcatggct gttctgctgc aactgtgctc     4560

cacgaaacag aagaaaaggt aaggtgttgt gtcacaaaga ggccccagtc tctttcttct     4620

tacatccatg cctcttacta gatgatacat ttacagattg ggcagtttgt tctcaaaacc     4680

tgggtgagaa gactattcct ggactctagc aacttcaaaa ctgaggctgg gtttcagaat     4740

ctttttctgc atcaattcag tcaatttgcc ttcaacaaag agaagtcagc aagttctatt     4800

tatgctgaaa gaactattcc atgagaaaag cagagaaccc caaagtgggc aggcaacccc     4860

gacgagagct tatccctgtg gcggcatcag gagtggctgt acattgaatt ttcaagtgct     4920

ggttggctgt cgccagccca tggtaggagg ggaggaatgg cttaagatga ggtaagatct     4980

ggtggtgggg catctttcct caattccata ctgactttga tcttgagaaa gaaaaactgg     5040

ctatgcatta cctaaaacca gtccaaaatg aaacagacca acacacacac aaaagcaaat     5100

tgtcaatccc tttggaatta agggaagcag cataaggttt ttctttttgg aaaaaatgca     5160

tttattttct ttttctccaa cagcaagaat cttttgtttt cattttgcac gtgaccttat     5220

cttggaaact cttataccca attgcctccc ctcctattat tcagagcttc cctgtctttt     5280

tacttgaaga caaataagtt tgagcacttg agtaaaactt cacaggtgtg taagtaggaa     5340

ggcaacattt tcaaaaagag accatatgat gagaacgcct aatgatcacc acatgcaaac     5400

aaacaaaact gccagtctca tttcccacat ttcttactta agagaagaga agtaaatgaa     5460

aggaagaaga aatagatttg taattaaaga tgtggcaaaa aagatagggc tgagccagtt     5520

caatttagcc ttcaggtgca gaatacttag agtccaaaga aatgtggagt ggacttaatt     5580

agatgcagtt gtctttatcc tgaaagtagt gagctaagcc taatttccag cattttgaaa     5640

gagattcctt tttgtttctt tccatggtgc cctctttaag gcacagagtt gctccacacc     5700

actgggtgga gaaagaaaga ttgcgaaccc tcgaccatcc ttttgaggct acattctatg     5760

ttatttggca gatttataaa gctatcagta ataacaatgc tatgtactgc aagctgccct     5820

tgtgttagtt aaagggagca tttttaatcg ttcggaaatt ttcgtgacat gtcaagtgca     5880

gttgtgagga ctgtgtgggt gaacgaaaat gtgtctgtca agttcagagt cctttagatt     5940

taaaaaaaaa ttatgactta tcaatggtgc cgttatagct gtgtcagaca atgggtgtgc     6000

ccattctcac aattatcctt caaaaaaaat ctatgttcaa atgctttaaa aatttatcac     6060

acgatacaag agtatgactt tgtcagcctt ctagagttct ttttttcttt tattttcttt     6120

cgtatttttt ccttcaaaaa atcaatgaag acttgatttc tgtcaataat tgtatcaagg     6180

gtgaatatac tacctgaatt ttgtgcatgt tacattgtag ttgtaacctt ttctaattca     6240

ggatgaatac gagatggttg tgattgtgca gtgtaccaat aaagttcgag aaatttgtaa     6300


<210>  1567
<211>  5225
<212>  DNA
<213>  homo sapiens

<400>  1567
gcctttggct tcagcgcttc gcccccgcgc tgtgccctct gtcggcggcg tggggcagct       60

gtagcagcgt tggcggcagg aggcggcggc cgcgtcgacg tcgacccaga ctggagcgac      120

gtttaaagaa ggggcagaat cgctggggag tgcggcttct tcttgttggg ggactcccag      180

ccttccgcgc gtccggagga ggagaagcgg cggcgccggg aagcaggcat ggagagtaga      240

aaactgattt ctgctacaga cattcagtac tctggcagtc tgctgaactc cttgaatgag      300

caacgtggcc atggactctt ctgtgatgtt accgttattg tggaagaccg aaaattccgg      360

gctcacaaga atattctttc agcttctagt acctacttcc atcagctctt ctctgttgct      420

gggcaagttg ttgaactgag ctttataaga gcagagatct ttgcagaaat tctcaattat      480

atctatagtt ctaaaattgt tcgtgttaga tcagatttgc ttgatgagtt aattaaatca      540

gggcagttat taggagtgaa atttatagca gagcttggtg tcccattgtc acaggttaaa      600

agcatctcag gtacagcgca ggatggtaat actgagcctt tacctcctga ttctggtgac      660

aagaaccttg taatacagaa atcaaaagat gaagcccaag ataatggggc tactataatg      720

cctattataa cagagtcttt ttcattatct gccgaagatt atgaaatgaa aaagatcatt      780

gttaccgatt ctgatgatga tgatgatgat gtcatttttt gctccgagat tctgcccaca      840

aaggagactt tgccgagtaa taacacagtg gcacaggtcc aatctaaccc aggccctgtt      900

gctatttcag atgttgcacc tagtgctagc aataactcgc cccctttaac aaatatcaca      960

cctactcaga aacttcctac tcctgtgaat caggcaactt tgagccaaac acaaggaagt     1020

gaaaaattgt tggtatcttc agctccaaca catctgactc ccaatattat tttgttaaat     1080

cagacaccac tttctacacc accaaatgtc agttcttcac ttccaaatca tatgccctct     1140

tcaatcaatt tacttgtgca gaatcagcag acaccaaaca gtgctatttt aacaggaaac     1200

aaggccaatg aagaggagga ggaggaaata atagatgatg atgatgacac tattagctcc     1260

agtcctgact cggccgtcag taatacatct ttggtcccac aggctgatac ctcccaaaat     1320

accagttttg atggatcatt aatacagaag atgcagattc ctacacttct tcaagaacca     1380

ctttccaatt ccttaaaaat ttcagatata attactagaa atactaatga tccaggcgta     1440

ggatcaaaac atctaatgga gggtcagaag atcattactt tagatacagc tactgaaatt     1500

gaaggcttat cgactggttg caaggtttat gcaaatatcg gtgaagatac ttatgatata     1560

gtgatccctg tcaaagatga ccctgatgaa ggggaggcca gacttgagaa tgaaatacca     1620

aaaacgtctg gcagcgagat ggcaaacaaa cgtatgaaag taaaacatga tgatcactat     1680

gagttaatag tagatggaag ggtctattat atctgtattg tatgcaaaag gtcatatgtc     1740

tgtctgacaa gcttgcggag acattttaac attcattctt gggagaagaa gtatccgtgc     1800

cgttactgtg agaaggtatt tcctcttgca gaatatcgca caaagcatga aattcatcac     1860

acaggggagc gaaggtatca gtgtttggcc tgtggcaaat ctttcatcaa ctatcagttt     1920

atgtcttcac atataaagtc agttcatagt caagatcctt ctggggactc aaagctttat     1980

cgtttacatc catgcaggtc tttacaaatc agacaatatg catatctttc cgatagatca     2040

agcactattc ctgcaatgaa ggatgatggt attgggtata aggttgacac tggaaaagaa     2100

cctccagtag ggaccactac atctactcag aacaagccaa tgacctggga agatattttt     2160

attcagcagg aaaatgattc aatttttaaa caaaatgtaa cagatggcag tactgagttt     2220

gaatttataa taccagagtc ttactaaact cctttgaaat actagaaagt tttgttttgg     2280

atgatggggc aggggtttca gaagatctgt aaaacaaatt aaggtgcgaa caagttaatt     2340

tgatctgcca cattatctga aggaagtgta gtgggatttt tgttgataat ttttagaagc     2400

aaattttcct gaaagttttg agtagaggtg agaccccctc cccaagtatc tgtttatata     2460

gttagttttc agctcattta aaagaggcaa aaattaaaag cttggagaga tagtttcctg     2520

aatagaattt gaagcagtct gaatgttctt tgaaaataac tggagttatt agcataccct     2580

agtacatctt acagctttcc ccttccatgt tagcacttta ctgctgaatt ctcaattttc     2640

ttaacattga gacaataaat gtgtgttttg tcttgtatat ggcataaaga gtaaataagt     2700

tttagagttg ttctggaaaa tgtcagaata agtcagtact tgggttgtgt aatctgctag     2760

tccaagcgaa cagcaacctc ctgctaccct ccctctatga aaatagccat gcagacaagt     2820

ctctcatctg aagaacaaat tagatttagc taattagaat taatcctggc tttcattgcc     2880

atagtctgta aaagactttg gtggctagac cactttatac cttcgcagtg tggtctctgg     2940

gggcaaaaaa ctaatgaaaa caatctctgt aatggcagat aggaggagat gaaaagttct     3000

gttgcatgga tttttaattc tctggctacc acatagtaga gaatggaatg aagatttcct     3060

tttggcttct taaggttaaa aatattccca tgaacatgaa aattttcaaa ttttgaatct     3120

gaaagccacc aaatgtatct ttatgtataa atccttgtaa atgatagatt ccatgggtga     3180

gactttacat attttgggtg ggaggctact ggcatatatt tttaaatgtt catattgcgt     3240

agaatctcca ctaggaagtc tttatttgaa atagttgaat cagtgatcta gtattttcct     3300

ttcggcaaga tttgttaggt ttttacccct tctaaaataa gttttattcc atctgcaaat     3360

tgctgcaata ttatagtaat cagaaactac ataaggaatg ttatataggc ttgtcagttc     3420

ccatttttct tgacaacaat aaataccact tttaaaaatg acacatattt aaacacttag     3480

aaaataaagt taacacttac tgaagtgcta gtactaaact gtgctagtac taaaagaaaa     3540

caggttggaa catacatata gcctagcatt tataacagaa ttgttgaacg tctgtaaatg     3600

attttttttt tttttgcaaa ggaaaaaatt gatactggaa aagattgttg tgcatagtta     3660

ttagtcattt gtaaccttgc ttaagtattt cttagtccaa catagatatt ttctttctcc     3720

tgaccatgta ttttaaaata tagtctattt cttgactttg aacttaaagc tttaatcata     3780

atttctcatg tatacatcgt tcttctgatg gtaagctgga tttgaaggta gtggtttcag     3840

tgtttcttaa gttggtagct gagggtatca ggcatcagtt catgcaataa tacaagaaaa     3900

aaaatccttt gcttgccaag aggtagagtg atgtgcattt atctgttttc tgttctgtaa     3960

gtctagacct tcaaaccatt tgtaaactaa cccctgggaa atttgaaatt acctgataac     4020

ttaagactct gtgatctctg gaatcaccat atgtttcttt tttgtgtaga tattaataac     4080

attactcttt gactatagtg tgcactctga aatgtactca gtgaaaattt gttttgagtt     4140

tcattaatgc tatttcacca gttagacata attacttcta ccgatgtgaa tgatacggat     4200

gccggcagag cttccagatc tttcagactc aactgctagg tcaattagtt tgtcataata     4260

aaacttggca gattctacaa gtctattatg acaaaccagg aactaattct ataatggaaa     4320

actatccatt ctgaataata ggtatgtaat tatttgctgc tgctgctgtg ctctgtaaat     4380

tctgaatatg acatttaaac tctgtgccta ctaaaggtat cttctggagt ttttgggagg     4440

agagaaactg gaaaattaaa ttgtattttt gccagaagac tcttacttgc atgtgtctca     4500

gggtcttcag tttttctata agtttccata tccaaagttc agaattcatg tgaaatactt     4560

ctttggggca aaagtccttc attcctggta tttattggat tggaaatctg tagcaagatg     4620

ctgtttaaaa ttaccatatt gtttttttat cttatactta gctctctggc tattgaactt     4680

ccttttcttg tttgaagtta gcttcaaatt tgctcctatg ctaaattacc tgtaaatatt     4740

ctggatagga actacttgaa atagtaattt gttaaaagat atgacaaaat gaaaatgctt     4800

aaactacaga aatttaaaaa tgccataaca atcttgcgag actaacttta aaatatactt     4860

taaatgatta ttatgatttt ggtggtaacg atcccccaca cacaaccact atgaagaaat     4920

aatgccgcat ttttccccca ttgtaccaaa aagataaaaa aatggtaaac actgatcaag     4980

gtattttgta ttgtcaaggc atgcatattc taaagaatta aatgctaact taacagcact     5040

ggctttctgg ctggtcaact atatgaaacc ttgttcattc ctccgagtac tgtaatgttc     5100

acacttgtac aatcttccct gtcatgactt taagttctac ttttcattaa ccatggcctg     5160

atattagttc ttagagcttc ttgtggcaaa aataaaatga tttaattcta aaaaaaaaaa     5220

aaaaa                                                                 5225


<210>  1568
<211>  6076
<212>  DNA
<213>  homo sapiens

<400>  1568
aaaagtgaat acatgatttt atttaactca ttaataagga aattggtaag gtgttaaaac       60

caattcaaag gacaatccaa agaacagatc aggaatacta aaataaatat gcaagcggag      120

gtgaaactgt tttccttggt agtggtggag gggaaggatt gctactccgc tggataaagt      180

tcatttgtgt atatataaat aagaattatt ttccattgtt atttatctat aacttataaa      240

gttgtaaaca acttccacgg aatcagactc aacctggaag ggtatggtct ctaggcaatg      300

caaaaatttt cccctacacc tgttaacaac tataatatct ccagacagag tagacagaaa      360

gtctggatgg caacgggaat ctactggtca tacggctaac ttcctaattc aataagcacg      420

tgactaaagg attttttcct tccactcaga tatttcaggc taactagata ctgtgtgctt      480

cttagtgtca ctgcttagtg ggggagccag ctctgagtgg ggtcatatcc ggacaagcga      540

atgagctatt tattcaatga ccacgcaaca ctccaaatcc tcccagggca acttgaaagt      600

aaccgcacct tccaaagggc accgtgcaat cagactgtgt gtttggcctc ctgtttgcta      660

gtggggagga agcggcttca tgggtgtaca ctacgcataa atgaatgtga aaggctattt      720

agacctctgc cttttcaccg tcctcccacc tgccacaggc tgggctcttg tgctagaaat      780

gacttgctag ctagacatca tggttcagga tctgagtcag aggtttaacc atttataagc      840

ttttttctta tgaaaaattg gcactaatta taatgtctaa ctgtcagagt tgttgcaggc      900

tttacaggag acgcgggctg tgaagatgct ttgtaaattg tgaagcgtta ttaaagaaca      960

catctttttt ttttaggaaa ccacagtgca aatttaattg ccggggaaga taacgggcct     1020

tggtgccctc caagcgtcag ctgagtttcc aagaagccgg gcagcgggcg cccgcgggtt     1080

cgtctctggc tcctcctccg ccacagcagc cgggggcccg ggtcggaggc ggcgggggcc     1140

gagcgcccgg cctcgcaagc ccacggcccg ctgggggtgc cgtcccgcgc cggggcggag     1200

caggccccgg cagcccagtt cctcattcta tcagcggtac aaggggctgg tggcgccaca     1260

ggcgctggga ccgcgggcgg acaaggatgg gtccgcgcgg cgcggcgagc ttgccccgag     1320

gccccggacc tcggcggctg ctcctccccg tcgtcctccc gctgctgctg ctgctgttgt     1380

tggcgccgcc gggctcgggc gccggggcca gccggccgcc ccacctggtc ttcttgctgg     1440

cagacgacct aggctggaac gacgtcggct tccacggctc ccgcatccgc acgccgcacc     1500

tggacgcgct ggcggccggc ggggtgctcc tggacaacta ctacacgcag ccgctgtgca     1560

cgccgtcgcg gagccagctg ctcactggcc gctaccagat ccgtacaggt ttacagcacc     1620

aaataatctg gccctgtcag cccagctgtg ttcctctgga tgaaaaactc ctgccccagc     1680

tcctaaaaga agcaggttat actacccata tggtcggaaa atggcacctg ggaatgtacc     1740

ggaaagaatg ccttccaacc cgccgaggat ttgataccta ctttggatat ctcctgggta     1800

gtgaagatta ttattcccat gaacgctgta cattaattga cgctctgaat gtcacacgat     1860

gtgctcttga ttttcgagat ggcgaagaag ttgcaacagg atataaaaat atgtattcaa     1920

caaacatatt caccaaaagg gctatagccc tcataactaa ccatccacca gagaagcctc     1980

tgtttctcta ccttgctctc cagtctgtgc atgagcccct tcaggtccct gaggaatact     2040

tgaagccata tgactttatc caagacaaga acaggcatca ctatgcagga atggtgtccc     2100

ttatggatga agcagtagga aatgtcactg cagctttaaa aagcagtggg ctctggaaca     2160

acacggtgtt catcttttct acagataacg gagggcagac tttggcaggg ggtaataact     2220

ggccccttcg aggaagaaaa tggagcctgt gggaaggagg cgtccgaggg gtgggctttg     2280

tggcaagccc cttgctgaag cagaagggcg tgaagaaccg ggagctcatc cacatctctg     2340

actggctgcc aacactcgtg aagctggcca ggggacacac caatggcaca aagcctctgg     2400

atggcttcga cgtgtggaaa accatcagtg aaggaagccc atcccccaga attgagctgc     2460

tgcataatat tgacccgaac ttcgtggact cttcaccgtg tcccaggaac agcatggctc     2520

cagcaaagga tgactcttct cttccagaat attcagcctt taacacatct gtccatgctg     2580

caattagaca tggaaattgg aaactcctca cgggctaccc aggctgtggt tactggttcc     2640

ctccaccgtc tcaatacaat gtttctgaga taccctcatc agacccacca accaagaccc     2700

tctggctctt tgatattgat cgggaccctg aagaaagaca tgacctgtcc agagaatatc     2760

ctcacatcgt cacaaagctc ctgtcccgcc tacagttcta ccataaacac tcagtccccg     2820

tgtacttccc tgcacaggac ccccgctgtg atcccaaggc cactggggtg tggggccctt     2880

ggatgtagga tttcagggag gctagaaaac ctttcaattg gaagttggac ctcaggcctt     2940

ttctcacgac tcttgtctca tttgttatcc caacctgggt tcacttggcc cttctcttgc     3000

tcttaaacca caccgaggtg tctaatttca acccctaatg catttaagaa gctgataaaa     3060

tctgcaacac tcctgctgtt ggctggagca tgtgtctaga ggtgggggtg gctgggttta     3120

tccccctttc ctaagccttg ggacagctgg gaacttaact tgaaatagga agttctcact     3180

gaatcctgga ggctggaaca gctggctctt ttagactcac aagtcagacg ttcgattccc     3240

ctctgccaat agccagtttt attggagtga atcacatttc ttacgcaaat gaagggagca     3300

gacagtgatt aatggttctg ttggccaagg cttctccctg tcggtgaagg atcatgttca     3360

ggcactccaa gtgaaccacc cctcttggtt caccccttac tcacttatct catcacagag     3420

cataaggccc attttgttgt tcaggtcaac agcaaaatgc ctgcaccatg actgtggctt     3480

ttaaaataaa gaaatgtgtt tttatcgtaa tttatttccc cccagccatt gctcactctg     3540

tctagacttc ctgccacttc caattcttct gtggcttttc ctgcctttcc ttttgacctc     3600

agtagtccta tccctgggaa ggccactttg cttctctacc tgagcacccc tgatttctgg     3660

aacgctgctg agccctgcct tacttttgcc cctagggctg aagctagagg cctccccgta     3720

ataggcggtg gagttgctct gtgaggatgt tcatggtaga cactaagagg gctgggtggg     3780

agatgcttgg ctctgtggca tctgttcagc gaggcttttc ctatattgca tggagttagt     3840

cattgtgatt gtagctttat ttcataatat attaagactt gcactgctat ttactagcag     3900

tgagaagaaa cctcaggaaa ggatatgaaa aagcaagtgg ccagtgtctg ggatactggg     3960

ccttggtaaa gcagaggagg gcacacccac agtcctctta ttctctgttt tactgcttgt     4020

tttgaggttc tggggtctgg caaagaggat gcagtttgac acctgcagcc ctttctcaat     4080

cccactaatg tcttactaat gtggaacagt ccatattagc tccagagagt gtcaaaccca     4140

gagaaatgtg tgcaaaaatg atactctttt ctgcattagc cccaccattg tgttcaccaa     4200

tgcttggaac actgcctgaa ggcactcatt ttttaatttt tattttattt ttaatttttt     4260

atatctttat gagacgatct cactctgtca ccaggttgga gtacagtggt acaatcacaa     4320

ctcaccgtag cctcaaactc ctgggctcaa gtgattctcc cacctcaggc acccaaatag     4380

ctggaactac aggcatatac cgccacaccc agctaatttt attttttgaa aagacaaggt     4440

tccctatgtt gcccagctgg tcttaaactc ctgggctcca gcaattatcc cagcttgggc     4500

tccaaaagtg ctgggattac aggcatgagt caccatgcct ggcctcattt tttaaaacaa     4560

atgaataaat ggacaaatga gtaaatgaga aagtctcaca ccatgaaaga tgctagtcca     4620

atgagctgaa tacagaggta atataaatgt cttccagctg ttgcttttct gttctcaagc     4680

tgcccctcct ggggtaggag cataatctac atcactgggc agtcacagga cactctatag     4740

caaggttgta gcgtcctctc cagtgggggg agaaaaggaa ctgtgcctac caaaggtact     4800

ctcttgtcag caatttccat ttctatactt tatgggacac tagaaactaa aagcaacaaa     4860

taatctgata taagtccttg tatagtcatc cttcaattca gtagcaatat tttctggtca     4920

ctactaacct gtattgtatt aaaatgagac tattggaagg aaatggtgct aaaactaata     4980

acatctctta ccaaccttta cccaactcct gggttggcaa acagctgacc aaactgccat     5040

cacctcccac ttggaagtgt atggccgaca gcatgaaata gctgagccca gatgttcctt     5100

ctgcatcctc cgaatcccag ggctgggtgt aggtagccgt tggaggccat cgctacaggg     5160

cacctatctg ttatcgctgc tgtcctccca acagctgtct ccagttctag ttccttggtt     5220

ttcaggcaca gtgggggatg ttctgcaccc agtggacttc aaaagagttt tgaagactta     5280

attttttgta aaacaagtac ttgagatttt ggtttatcca taatagaatg tatttcatta     5340

gattctctga ttctatataa gaatgtgaaa agattgatat attgttgtta gaaataatgt     5400

tatttctttc caattttttt tttttttttt tttgagatgg agtctcgctc tgtcacccag     5460

gctggagtgc agtggtgtga tctcggctca ctgcagcctc taactcccag gttcaagcta     5520

ttctcctgcc tcagcctccc aagtagctgg attacaggca tacaccacca cgcctggcta     5580

tgttttgtat ttttcgtaga gatagggttt caccatgttg gccaggctgg tctcaaactc     5640

ctgacctcaa gtgatccacc cacttcagct tcccaaagca ctgggattac aggtgtgagc     5700

cactgtgccc ggcaaatttt tttaccttta cagaaggttt tgcttattta attgtgagct     5760

catttttctt tgttactttt gtccccccag atttggggga caaaataaaa ttaatctttt     5820

aaaatgtgtc agccatatgt atggggcttc catttggggt gaggagaaag ttctggaact     5880

agatagtggt catggttata caacatcata aatgcaatta ctgccactga attgtatgtt     5940

ttaaagtggt taaaatgtta agttttatgt tttattacaa tttttaaatg tgtcaaccaa     6000

ctttatagta cataaattat atctcagtaa agctgttaaa taaataaata tagtaaaaat     6060

tttagaacta aaaaaa                                                     6076


<210>  1569
<211>  2270
<212>  DNA
<213>  homo sapiens

<400>  1569
aatggggcgc cgactcggcg caggaacaag gcgggggttc ggggccggct gcagactctc       60

accgcagcgg ccaggaacgc cagccgttca cgcgttcggt cctccttggc tgactcaccg      120

ccctggccgc cgcaccatgg acgcccccag gcaggtggtc aactttgggc ctggtcccgc      180

caagctgccg cactcagtgt tgttagagat acaaaaggaa ttattagact acaaaggagt      240

tggcattagt gttcttgaaa tgagtcacag gtcatcagat tttgccaaga ttattaacaa      300

tacagagaat cttgtgcggg aattgctagc tgttccagac aactataagg tgatttttct      360

gcaaggaggt gggtgcggcc agttcagtgc tgtcccctta aacctcattg gcttgaaagc      420

aggaaggtgt gctgactatg tggtgacagg agcttggtca gctaaggccg cagaagaagc      480

caagaagttt gggactataa atatcgttca ccctaaactt gggagttata caaaaattcc      540

agatccaagc acctggaacc tcaacccaga tgcctcctac gtgtattatt gcgcaaatga      600

gacggtgcat ggtgtggagt ttgactttat acccgatgtc aagggagcag tactggtttg      660

tgacatgtcc tcaaacttcc tgtccaagcc agtggatgtt tccaagtttg gtgtgatttt      720

tgctggtgcc cagaagaatg ttggctctgc tggggtcacc gtggtgattg tccgtgatga      780

cctgctgggg tttgccctcc gagagtgccc ctcggtcctg gaatacaagg tgcaggctgg      840

aaacagctcc ttgtacaaca cgcctccatg tttcagcatc tacgtcatgg gcttggttct      900

ggagtggatt aaaaacaatg gaggtgccgc ggccatggag aagcttagct ccatcaaatc      960

tcaaacaatt tatgagatta ttgataattc tcaaggattc tacgtttgtc cagtggagcc     1020

ccaaaataga agcaagatga atattccatt ccgcattggc aatgccaaag gagatgatgc     1080

tttagaaaaa agatttcttg ataaagctct tgaactcaat atgttgtcct tgaaagggca     1140

taggtctgtg ggaggcatcc gggcctctct gtataatgct gtcacaattg aagacgttca     1200

gaagctggcc gccttcatga aaaaattttt ggagatgcat cagctatgaa cacatcctaa     1260

ccaggatata ctctgttctt gaacaacata caaagtttaa agtaacttgg ggatggctac     1320

aaaaagttaa cacagtattt ttctcaaatg aacatgttta ttgcagattc ttcttttttg     1380

aaagaacaac agcaaaacat ccacaactct gtaaagctgg tgggacctaa tgtcacctta     1440

attctgactt gaactggaag cattttaaga aatcttgttg cttttctaac aaattcccgc     1500

gtattttgcc tttgctgcta ctttttctag ttagatttca aacttgcctg tggacttaat     1560

aatgcaagtt gcgattaatt atttctggag tcatgggaac acacagcaca gagggtaggg     1620

gggccctcta ggtgctgaat ctacacatct gtggggtctc ctgggttcag cggctgttga     1680

ttcaaggtca acattgacca ttggaggagt ggtttaagag tgccaggcga agggcaaact     1740

gtagatcgat ctttatgctg ttattacagg agaagtgaca tactttatat atgtttatat     1800

tagcaaggtc tgtttttaat accatatact ttatatttct atacatttat atttctaata     1860

atacagttat cactgatata tgtagacact tttagaattt attaaatcct tgaccttgtg     1920

cattatagca ttccattagc aagagttgta ccccctcccc agtcttcgcc ttcctctttt     1980

taagctgttt tatgaaaaag acctagaagt tcttgattca tttttaccat tctttccata     2040

ggtagaagag aaagttgatt ggttggttgt ttttcaatta tgccattaaa ctaaacattt     2100

ctgttaaatt accctatcct ttgttctcta ctgttttctt tgtaatgtat gactacgaga     2160

gtgatacttt gctgaaaagt ctttccccta ttgtttatct attgtcagta ttttatgttg     2220

aatatgtaaa gaacattaaa gtcctaaaac atctaaaaaa aaaaaaaaaa                2270


<210>  1570
<211>  7247
<212>  DNA
<213>  homo sapiens

<400>  1570
atatatcatt gttttctgtc ttcctcatta gatttatgta ggttggaact ttgttctgtt       60

tatctctata atcctattac ctagaactgt gcctggtaaa taagagctta gtatgtattt      120

actgaatgat gaattaatat atttatatat tgaggctgtg tcttctaatg tcagcaaaat      180

aattgacaag agactttggt ggacactgtt ctctcttggt taatattttt ggaaaaaaca      240

actcccttaa atttgggtaa atgtggtaat ttgagcgaag taagtacttc tgttttctct      300

aagtagactt ggatttacta gactttgtaa tgagtaattt ctttgttctt cctacctgga      360

ggaaggactt aactgtagta tgccattaaa aattgcactt atatcatctt acatgttaat      420

ttttatgatt atactaatga gtaatgtttt tcttttcttt taaaaaattt gtagatctaa      480

cagctttaat acagatagaa acatagataa atataactat accttgtgga aaggacagct      540

tttaaataaa ggaaaacttt tgtgttatat ttctctgagg tcagccactc gtgctttttt      600

gcctatcaaa ctacctgaga aattagatgt tgaaacagtt atgagtattg atcatctgaa      660

acagaaaatc cctccagcac tgttttataa ggaaacatac ttaggtccaa atgaagtttt      720

gaagaatgga atgtattgca gcctttatga agttgtggaa aagacaagaa ttggaagtaa      780

catggagagt ttactgcaaa aactagacag agaaaaactt gttcttgtta aacctttggg      840

agaccgagga tacctttttc ttctctcccc ttatcagatg gttcctccat atgaatatca      900

gactgccaag tctcgagtcc tacatgcttt gtttctattt caagaaccta gaagcatagt      960

tacttcacaa aaaggttcaa ccaatgcagc accacaggag aggcatgaga gcatgccaga     1020

tgtattaaaa atagctcagt ttttacaatt ttctttgatt cagtgtcgaa aggaattcaa     1080

aaatataagc gccataaatt ttcattctgt tgttgaaaag tatgtaagtg aattttttaa     1140

gcgaggtttt ggttcaggta aacgagagtt tattatgttt ccatatgatt cacgattaga     1200

tgataaaaaa ttcttatact cagctcccag aaataaatcc catattgata cttgtttgca     1260

tgcctatatt tttcggcctg aagtgtatca gttacctatt tgtaaattaa aagaactatt     1320

tgaagaaaat agaaaacttc agcagtttag tccactttca gattatgaag gtcaagaaga     1380

agaaatgaat ggtacaaaaa tgaaatttgg aaaacgaaat aactcaagag gtgaagccat     1440

tatatctgga aagcaaagat catctcattc tttggattat gataaggata gagtcaaaga     1500

attgattaat ttaattcagt gtaggaaaaa gagtgtgggt ggggactcag acacagaaga     1560

tatgagaagc aaaactgtct tgaagaggaa gcttgaggat ctacctgaaa atatgagaaa     1620

gctcgccaaa accagtaatt tatctgaaaa ttgccatctg tatgaagagt ctccacagcc     1680

tattggctca cttggacatg atgctgactt gaggcggcag cagcaggata cctgtaactc     1740

cggcattgct gacatccata ggctgtttaa ttggttatca gaaacactag caaatgcgcg     1800

ccattctgat gcatctctga cagacacagt caacaaagcc ttaggattga gcactgatga     1860

tgcctatgaa gagctgaggc aaaaacatga gtatgagttg aactctaccc cagataagaa     1920

agactatgag cagcctactt gtgcaaaagt tgaaaatgca cagtttaagg gtactcagag     1980

cttattacta gaagttgatg caacatctaa gtattctgtt gctatttcta ccagcgaagt     2040

gggcactgac cataagctac atttgaaaga agatccaaat ttaattagcg tgaataattt     2100

tgaagattgc agtttgtgtc ccagtgttcc cattgaacat ggatttcgta gacaacagtc     2160

taagtcaaat aatgttgaag agactgaaat acattggaaa ctgattccaa ttacaggagg     2220

gaatgcaaga agcccagaag accagctggg gaaacatggt gagaaacaaa caccagacac     2280

actaaagggc accactgagg atgacgtgtt gacaggtcag gtggaggagc agtgtgtgcc     2340

agcagcagag gcagagccgc ctgcagtgag cgaaaccaca gagaggacag tgttaggaga     2400

gtacaatctc ttttctagga agatagaaga gattttgaag caaaagaatg tttcatatgt     2460

cagtacagtt tccacaccta tcttttcaac acaagagaag atgaaacggc tttccgagtt     2520

catatattct aagacttcca aagctggtgt gcaggagttt gtagatggtt tgcatgagaa     2580

gctaaatact attattatta aagcatcagc caagggtggg aatttgccac cagtcagtcc     2640

taacgattct ggtgctaaga tagcatcgaa tcctctggaa aggcatgtca taccagtttc     2700

ctcaagtgac ttcaacaata aacatctcct tgagccactg tgtagtgatc ctttgaaaga     2760

taccaactct gatgagcagc attccacttc ggctttaact gaagtagaaa tgaaccagcc     2820

tcaacatgcc acagagttaa tggtgacttc tgatcatatt gtacctggtg atatggcccg     2880

ggaaccagta gaagaaacaa caaaatcccc cagtgatgta aacatttctg ctcaaccagc     2940

tctttcaaat tttataagcc agttagaacc tgaagtattt aatagtttgg ttaaaatcat     3000

gaaagacgtc cagaaaaata ctgtgaaatt ttatattcat gaagaagaag agagtgtgct     3060

ctgtaaagaa ataaaggaat atcttatcaa attaggcaat acagaatgtc atcctgaaca     3120

gtttttggaa agaagatcaa aattagataa actattgatt attattcaaa atgaagacat     3180

tgcaggtttc attcacaaga tacctggctt ggtgacttta aagaagctcc cctgtgttag     3240

ttttgctggt gttgatagcc tggatgatgt taaaaatcat acatacaatg aattatttgt     3300

atctggaggt tttatcgtat ctgatgaatc aattctaaac ccagaggttg tcacagttga     3360

gaaccttaaa aattttttga cattccttga ggaacttagt actccagaag gaaaatggca     3420

atggaaagtc cactgtaaat ttcagaagaa actaaaggaa ctaggcagat tgaatgctaa     3480

agctctaagt ctgttgacgc ttctgaatgt ctatcagaag aaacatctgg ttgaaatttt     3540

gtcataccac aattgtgatt cacaaactcg aaatgctcca gaattggatt gccttatcag     3600

acttcaggct cagaacatac agcaacgaca catagtcttt ttaacagaga agaacatcaa     3660

gatgctttcc agttatacag ataatggaat agtggttgca actgctgaag acttcatgca     3720

aaactttaaa aatcttgtgg gctatcacaa ttcaatcaca gaagaaaacc ttccacagct     3780

tggtgctaat gagaatcttg agtcgcagtc agctctttta gaaaacgatg aaaaggatga     3840

agaggatatg tctctggatt caggggatga aatctcacat atagaagtat gcagcaattt     3900

tcattcagaa atatgggaga aagagaccaa aggatcacgt ggaacagatc aaaaaaagaa     3960

tactcaaatt gagttgcaat cgtctcctga tgtgcaaaac agtttattag aagataagac     4020

ttaccttgat tctgaagaga gaacttctat tgatatagta tgctctgaag gagagaacag     4080

caattcaaca gaacaagatt catatagtaa ctttcaggtt tatcatagtc aattaaatat     4140

gtcccatcag tttagtcatt ttaatgttct cactcatcag acatttttgg ggacaccata     4200

tgccctttca tcaagtcagt ctcaagaaaa tgagaattac ttcttatctg cttatactga     4260

aagcttggat agagataaat ctccacctcc cttaagttgg gggaaaagtg attcttccag     4320

gccatattca caagagaaat aactgtagta actttttttt taagagattg ttgtggactt     4380

tgtttattaa caatttatat ttcattctct aaacaaaagg ttcttgttct ttctcaaatg     4440

ttttttcttt tatttaaatc atgatggcct gtaacagttg aagcatctaa aaattgaaat     4500

aaatatatat ttttaacata tattgtactt gaattatctc atgttggcac ttctaagttt     4560

tactttttgt atgttacctg tacttaggct tcaaattgaa gcctgtttta tgtgtaaaat     4620

cagatgcttg caggaggacg gtaaacagca aaggctttac ttctttttct ctaatgtcac     4680

ctgatataaa gtacttttgt tgaagtgaat tattttgatg taggcttttg tatactgtgt     4740

ttacacaggt ataagtcagt aatagcagtg ttaatattta caggattttg gctcgatacc     4800

tcaagattta tctaacagtg cagtttcatt tagataataa actatgtaca taggacacat     4860

tttttatctc taggcttagt catgtaaaaa ctgcctattg ctaaaattct ggtaactttt     4920

tgagagtatt ggataatttt cagtacctgc gcaatccttg atttaatgaa attaaatttt     4980

ttatttcaaa agataggctt ctgtttatca aaggcgttga acaatttgat ttttaaatta     5040

gttttagcaa aatggaagta taatgggaat atatttttga ggtggtctta gtagtaatta     5100

ccatttgttg aacacattaa tgctatacta gacagataca gtggagatag ctttcaaacc     5160

cgtatctatt cctaactact gcctctaata ctaattacta acttgttact aatgctaact     5220

tttaaaaatg tttttgaaaa ttgcaatttc tacaaataaa tgtcatagtg caaataaatg     5280

tcaggattta gagaaggagc ctaaactgaa tttgtgttat ttcagtaaaa gttatggagt     5340

tatgggtcta gacgtgttaa taagttagac agaactttgg cactttagaa caaatgcatg     5400

agtggtattt cagttcctaa gttacataaa aagtgtgaaa gaacactgtg aggtcccagc     5460

aacgccagac tatattaagg taagtagaaa gtgtttttat agggcttcaa tacccaggtg     5520

gtgacagagc agaagaaccg gttttttttt tttttttttt actactaagc ttttacaaaa     5580

gaagtatctg ttttattgta tagaacaagt acagcatttt actacatagt atacaagttt     5640

ttaatgagca tttaaaaaaa taagtaaatc taggctattt gaaaaataca gttgagccag     5700

tgagcacatt ttataatttg gaagacacaa atcaaatgtg aaggatttga ttttctacat     5760

ttaaaatgaa gaaccaaaac tctcttcttg attttcagct aaaggcagga gactactttc     5820

caactccttt tgcttctgga gaaggccctg aaatcacatt gatatatgtt tgttagtaaa     5880

atgtgcacac ctgacttgca atgttgtgtt aaactagaat tatattcact tggaaaacat     5940

atcgcttagg ataaaatttt gtcattcaaa aattttttca gaaatgcttg tactagacca     6000

cctcatttgg atatatagct atcacatttg taagattctg tttttagcat aaaaatcaat     6060

agggatgaaa attttcttag aactcaagac tccataacta tgggggtaaa tgaagtcatc     6120

ccttctcccc cagtccaccc ccaagtgctc ttagatactg aaggagtctc ccttaacata     6180

cagtgttttt tttttgttgt tgttgttttg tttttttttg gagatggagt ctcgctctgt     6240

cgcccaagct ggagtacagt ggtgcaatct cactgcaagc tctgcctccc aggttcacac     6300

cattctcctg cctcaacctc ccgaatggct gggactacag gcacccacca ccacgcctgg     6360

ctaactaact aactaacttt ttgtattttt agtagagaca gggtttcact gtgttagcca     6420

ggatggtctt gatctcctga cctcatgatc tgcctgcctc agcctcccaa agtgctggga     6480

ttacaggctt gagccactgc tcctggccaa catccagtat tttatcttga ctgtcctaac     6540

cttaccttag atgctaacag aagggtcctg ctgaaataac actgggtgct atattgatgg     6600

gtaaatgtgt acatcctatt ccttcctctt tatctcacaa tttttgtctc cactaagcaa     6660

gaagtaaact aacacttcgt cactctaaag aaataactta tgtaaaactc ttagtaaccc     6720

tgtttgtctt caaatgagta aatagaccaa agtgggggga caattttcta gttctgtaga     6780

gggaaaaaca tctgagtcaa cattttgaaa tgcagagggt attggtacat gacgacatgg     6840

aaaagggcac ttttaaacac agcttactct tcctcaagta cagagagtat atagtgaatc     6900

aaaactaact acagccattc tttttaaagc ccaagggatg gagcaaaggt gtaaggatgt     6960

tacctgtttg ttttaatcag agagcaaaaa gaagtcacaa tagtttggga gaaaaagtag     7020

tatggtgagt aaggttatgc gtataatttc atactgaatt tattactatt tgggatgtac     7080

gtcaatgttc taacaaacac tgccaacacg tcaatttttt aaaaagcgtg ggccacattg     7140

ctaagaattt gttaaagcat aactgtattt tttgttttag ggccttattg atgttttgcc     7200

gttccaatgt atgcattttt ttactcaata aacttgtctt aatttta                   7247


<210>  1571
<211>  8296
<212>  DNA
<213>  homo sapiens

<400>  1571
ggctgagagc agctcggcgg cgagactggc ccgccgcccc ttccccccac acccgtcgac       60

cttgtgggca gaagcttccc agagctcctt aggccggcgc gatggcgact gctgtggaga      120

cggaggcctg tcagccgacg gatgcgagtt gggaaagtgg cggcggcgga gacgacgaga      180

tgaagcaggc gcttccggag cttgagtcct cccaacaaaa tggcggcggc ggcggcctca      240

acatcgctga gcccagcggc ggcgctgggc gtgaggagaa cgcgggggcc gaggccgccc      300

agagcctcag ccacgagcag cctcaggact cctctgaggc gggcgcggcc gccctgccca      360

gaggccccga agagcccgaa aggcctgtta ggaggagttt tcagatcccc aggaagagca      420

gagaaaagaa agcacttttc cagccattaa ctccaggctc tcgagaattt gaagatgttg      480

taaatattct ccattcttct taccttgaac caacctcagt aacaaatttt aactacagac      540

gtgcttgctt ggtacacaat gagcttttgg aaaaggagtt tacagaaaag cgaagagaac      600

tgaagtttga tggtcgttta gataaggaac tttcagaatc ctatgcattt ctgatggttg      660

atcgatacca ggttcaaacc atatgtgaaa aaggattaca tgtgggtcag tccaaaataa      720

caattcttgg cagtccttcc atgggtgtct atctttctag gtatgctgat ttattacaag      780

cgaatccttt ggacacgggg gcaatgggtg atgttgttat ttttaaaata atgaagggta      840

aaataaagag tatatatgac cccatgggtg taaaaagttt ggaatctatg ttaaataaga      900

gtgctttgga ccccacacca aagcatgaat gtcacgtgtc aaagaatgcc aatcgaatta      960

catcactttt ggcttacaga gcctatgagc ttactcagta ttatttttat gagtatggct     1020

ttgatgagct aaggcgaaga ccaagacacg tttgtccata tgcagttgtg tcttttactt     1080

acaaagatga tatacaaact ccgaagtttg taccttcatc aagatctaac agctttaata     1140

cagatagaaa catagataaa tataactata ccttgtggaa aggacagctt ttaaataaag     1200

gaaaactttt gtgttatatt tctctgaggt cagccactcg tgcttttttg cctatcaaac     1260

tacctgagaa attagatgtt gaaacagtta tgagtattga tcatctgaaa cagaaaatcc     1320

ctccagcact gttttataag gaaacatact taggtccaaa tgaagttttg aagaatggaa     1380

tgtattgcag cctttatgaa gttgtggaaa agacaagaat tggaagtaac atggagagtt     1440

tactgcaaaa actagacaga gaaaaacttg ttcttgttaa acctttggga gaccgaggat     1500

acctttttct tctctcccct tatcagatgg ttcctccata tgaatatcag actgccaagt     1560

ctcgagtcct acatgctttg tttctatttc aagaacctag aagcatagtt acttcacaaa     1620

aaggttcaac caatgcagca ccacaggaga ggcatgagag catgccagat gtattaaaaa     1680

tagctcagtt tttacaattt tctttgattc agtgtcgaaa ggaattcaaa aatataagcg     1740

ccataaattt tcattctgtt gttgaaaagt atgtaagtga attttttaag cgaggttttg     1800

gttcaggtaa acgagagttt attatgtttc catatgattc acgattagat gataaaaaat     1860

tcttatactc agctcccaga aataaatccc atattgatac ttgtttgcat gcctatattt     1920

ttcggcctga agtgtatcag ttacctattt gtaaattaaa agaactattt gaagaaaata     1980

gaaaacttca gcagtttagt ccactttcag attatgaagg tcaagaagaa gaaatgaatg     2040

gtacaaaaat gaaatttgga aaacgaaata actcaagagg tgaagccatt atatctggaa     2100

agcaaagatc atctcattct ttggattatg ataaggatag agtcaaagaa ttgattaatt     2160

taattcagtg taggaaaaag agtgtgggtg gggactcaga cacagaagat atgagaagca     2220

aaactgtctt gaagaggaag cttgaggatc tacctgaaaa tatgagaaag ctcgccaaaa     2280

ccagtaattt atctgaaaat tgccatctgt atgaagagtc tccacagcct attggctcac     2340

ttggacatga tgctgacttg aggcggcagc agcaggatac ctgtaactcc ggcattgctg     2400

acatccatag gctgtttaat tggttatcag aaacactagc aaatgcgcgc cattctgatg     2460

catctctgac agacacagtc aacaaagcct taggattgag cactgatgat gcctatgaag     2520

agctgaggca aaaacatgag tatgagttga actctacccc agataagaaa gactatgagc     2580

agcctacttg tgcaaaagtt gaaaatgcac agtttaaggg tactcagagc ttattactag     2640

aagttgatgc aacatctaag tattctgttg ctatttctac cagcgaagtg ggcactgacc     2700

ataagctaca tttgaaagaa gatccaaatt taattagcgt gaataatttt gaagattgca     2760

gtttgtgtcc cagtgttccc attgaacatg gatttcgtag acaacagtct aagtcaaata     2820

atgttgaaga gactgaaata cattggaaac tgattccaat tacaggaggg aatgcaagaa     2880

gcccagaaga ccagctgggg aaacatggtg agaaacaaac accaggtatg aaatcaccag     2940

aagaacaact ggtgtgtgtg ccaccacagg aggcctttcc taacgacccc cgggtaataa     3000

atagacagag aagttctgat taccagtttc catcctctcc atttacagac acactaaagg     3060

gcaccactga ggatgacgtg ttgacaggtc aggtggagga gcagtgtgtg ccagcagcag     3120

aggcagagcc gcctgcagtg agcgaaacca cagagaggac agtgttagga gagtacaatc     3180

tcttttctag gaagatagaa gagattttga agcaaaagaa tgtttcatat gtcagtacag     3240

tttccacacc tatcttttca acacaagaga agatgaaacg gctttccgag ttcatatatt     3300

ctaagacttc caaagctggt gtgcaggagt ttgtagatgg tttgcatgag aagctaaata     3360

ctattattat taaagcatca gccaagggtg ggaatttgcc accagtcagt cctaacgatt     3420

ctggtgctaa gatagcatcg aatcctctgg aaaggcatgt cataccagtt tcctcaagtg     3480

acttcaacaa taaacatctc cttgagccac tgtgtagtga tcctttgaaa gataccaact     3540

ctgatgagca gcattccact tcggctttaa ctgaagtaga aatgaaccag cctcaacatg     3600

ccacagagtt aatggtgact tctgatcata ttgtacctgg tgatatggcc cgggaaccag     3660

tagaagaaac aacaaaatcc cccagtgatg taaacatttc tgctcaacca gctctttcaa     3720

attttataag ccagttagaa cctgaagtat ttaatagttt ggttaaaatc atgaaagacg     3780

tccagaaaaa tactgtgaaa ttttatattc atgaagaaga agagagtgtg ctctgtaaag     3840

aaataaagga atatcttatc aaattaggca atacagaatg tcatcctgaa cagtttttgg     3900

aaagaagatc aaaattagat aaactattga ttattattca aaatgaagac attgcaggtt     3960

tcattcacaa gatacctggc ttggtgactt taaagaagct cccctgtgtt agttttgctg     4020

gtgttgatag cctggatgat gttaaaaatc atacatacaa tgaattattt gtatctggag     4080

gttttatcgt atctgatgaa tcaattctaa acccagaggt tgtcacagtt gagaacctta     4140

aaaatttttt gacattcctt gaggaactta gtactccaga aggaaaatgg caatggaaag     4200

tccactgtaa atttcagaag aaactaaagg aactaggcag attgaatgct aaagctctaa     4260

gtctgttgac gcttctgaat gtctatcaga agaaacatct ggttgaaatt ttgtcatacc     4320

acaattgtga ttcacaaact cgaaatgctc cagaattgga ttgccttatc agacttcagg     4380

ctcagaacat acagcaacga cacatagtct ttttaacaga gaagaacatc aagatgcttt     4440

ccagttatac agataatgga atagtggttg caactgctga agacttcatg caaaacttta     4500

aaaatcttgt gggctatcac aattcaatca cagaagaaaa ccttccacag cttggtgcta     4560

atgagaatct tgagtcgcag tcagatgctg ttttgacatt aacccctttg gagctgggag     4620

ttgggatttc ccaacattaa acgtgaacac atttcgcaga agcttttagc atcggattat     4680

ctggacattc acatctagtg tgagtgttgt gactaagtga acttgtggca gaagaccaag     4740

ctttaaggga ttgtggactt gcagaccctg acgcgttata ttgtgtgagt agtgtataat     4800

tttaaaactt aaacaaactg tgtatttcaa tagaggagga ctttttgttt tttaaatgta     4860

gctcttttag aaaacgatga aaaggatgaa gaggatatgt ctctggattc aggggatgaa     4920

atctcacata tagaagtatg cagcaatttt cattcagaaa tatgggagaa agagaccaaa     4980

ggatcacgtg gaacagatca aaaaaagaat actcaaattg agttgcaatc gtctcctgat     5040

gtgcaaaaca gtttattaga agataagact taccttgatt ctgaagagag aacttctatt     5100

gatatagtat gctctgaagg agagaacagc aattcaacag aacaagattc atatagtaac     5160

tttcaggttt atcatagtca attaaatatg tcccatcagt ttagtcattt taatgttctc     5220

actcatcaga catttttggg gacaccatat gccctttcat caagtcagtc tcaagaaaat     5280

gagaattact tcttatctgc ttatactgaa agcttggata gagataaatc tccacctccc     5340

ttaagttggg ggaaaagtga ttcttccagg ccatattcac aagagaaata actgtagtaa     5400

cttttttttt aagagattgt tgtggacttt gtttattaac aatttatatt tcattctcta     5460

aacaaaaggt tcttgttctt tctcaaatgt tttttctttt atttaaatca tgatggcctg     5520

taacagttga agcatctaaa aattgaaata aatatatatt tttaacatat attgtacttg     5580

aattatctca tgttggcact tctaagtttt actttttgta tgttacctgt acttaggctt     5640

caaattgaag cctgttttat gtgtaaaatc agatgcttgc aggaggacgg taaacagcaa     5700

aggctttact tctttttctc taatgtcacc tgatataaag tacttttgtt gaagtgaatt     5760

attttgatgt aggcttttgt atactgtgtt tacacaggta taagtcagta atagcagtgt     5820

taatatttac aggattttgg ctcgatacct caagatttat ctaacagtgc agtttcattt     5880

agataataaa ctatgtacat aggacacatt ttttatctct aggcttagtc atgtaaaaac     5940

tgcctattgc taaaattctg gtaacttttt gagagtattg gataattttc agtacctgcg     6000

caatccttga tttaatgaaa ttaaattttt tatttcaaaa gataggcttc tgtttatcaa     6060

aggcgttgaa caatttgatt tttaaattag ttttagcaaa atggaagtat aatgggaata     6120

tatttttgag gtggtcttag tagtaattac catttgttga acacattaat gctatactag     6180

acagatacag tggagatagc tttcaaaccc gtatctattc ctaactactg cctctaatac     6240

taattactaa cttgttacta atgctaactt ttaaaaatgt ttttgaaaat tgcaatttct     6300

acaaataaat gtcatagtgc aaataaatgt caggatttag agaaggagcc taaactgaat     6360

ttgtgttatt tcagtaaaag ttatggagtt atgggtctag acgtgttaat aagttagaca     6420

gaactttggc actttagaac aaatgcatga gtggtatttc agttcctaag ttacataaaa     6480

agtgtgaaag aacactgtga ggtcccagca acgccagact atattaaggt aagtagaaag     6540

tgtttttata gggcttcaat acccaggtgg tgacagagca gaagaaccgg tttttttttt     6600

ttttttttta ctactaagct tttacaaaag aagtatctgt tttattgtat agaacaagta     6660

cagcatttta ctacatagta tacaagtttt taatgagcat ttaaaaaaat aagtaaatct     6720

aggctatttg aaaaatacag ttgagccagt gagcacattt tataatttgg aagacacaaa     6780

tcaaatgtga aggatttgat tttctacatt taaaatgaag aaccaaaact ctcttcttga     6840

ttttcagcta aaggcaggag actactttcc aactcctttt gcttctggag aaggccctga     6900

aatcacattg atatatgttt gttagtaaaa tgtgcacacc tgacttgcaa tgttgtgtta     6960

aactagaatt atattcactt ggaaaacata tcgcttagga taaaattttg tcattcaaaa     7020

attttttcag aaatgcttgt actagaccac ctcatttgga tatatagcta tcacatttgt     7080

aagattctgt ttttagcata aaaatcaata gggatgaaaa ttttcttaga actcaagact     7140

ccataactat gggggtaaat gaagtcatcc cttctccccc agtccacccc caagtgctct     7200

tagatactga aggagtctcc cttaacatac agtgtttttt ttttgttgtt gttgttttgt     7260

ttttttttgg agatggagtc tcgctctgtc gcccaagctg gagtacagtg gtgcaatctc     7320

actgcaagct ctgcctccca ggttcacacc attctcctgc ctcaacctcc cgaatggctg     7380

ggactacagg cacccaccac cacgcctggc taactaacta actaactttt tgtattttta     7440

gtagagacag ggtttcactg tgttagccag gatggtcttg atctcctgac ctcatgatct     7500

gcctgcctca gcctcccaaa gtgctgggat tacaggcttg agccactgct cctggccaac     7560

atccagtatt ttatcttgac tgtcctaacc ttaccttaga tgctaacaga agggtcctgc     7620

tgaaataaca ctgggtgcta tattgatggg taaatgtgta catcctattc cttcctcttt     7680

atctcacaat ttttgtctcc actaagcaag aagtaaacta acacttcgtc actctaaaga     7740

aataacttat gtaaaactct tagtaaccct gtttgtcttc aaatgagtaa atagaccaaa     7800

gtggggggac aattttctag ttctgtagag ggaaaaacat ctgagtcaac attttgaaat     7860

gcagagggta ttggtacatg acgacatgga aaagggcact tttaaacaca gcttactctt     7920

cctcaagtac agagagtata tagtgaatca aaactaacta cagccattct ttttaaagcc     7980

caagggatgg agcaaaggtg taaggatgtt acctgtttgt tttaatcaga gagcaaaaag     8040

aagtcacaat agtttgggag aaaaagtagt atggtgagta aggttatgcg tataatttca     8100

tactgaattt attactattt gggatgtacg tcaatgttct aacaaacact gccaacacgt     8160

caatttttta aaaagcgtgg gccacattgc taagaatttg ttaaagcata actgtatttt     8220

ttgttttagg gccttattga tgttttgccg ttccaatgta tgcatttttt tactcaataa     8280

acttgtctta atttta                                                     8296


<210>  1572
<211>  7247
<212>  DNA
<213>  homo sapiens

<400>  1572
atatatcatt gttttctgtc ttcctcatta gatttatgta ggttggaact ttgttctgtt       60

tatctctata atcctattac ctagaactgt gcctggtaaa taagagctta gtatgtattt      120

actgaatgat gaattaatat atttatatat tgaggctgtg tcttctaatg tcagcaaaat      180

aattgacaag agactttggt ggacactgtt ctctcttggt taatattttt ggaaaaaaca      240

actcccttaa atttgggtaa atgtggtaat ttgagcgaag taagtacttc tgttttctct      300

aagtagactt ggatttacta gactttgtaa tgagtaattt ctttgttctt cctacctgga      360

ggaaggactt aactgtagta tgccattaaa aattgcactt atatcatctt acatgttaat      420

ttttatgatt atactaatga gtaatgtttt tcttttcttt taaaaaattt gtagatctaa      480

cagctttaat acagatagaa acatagataa atataactat accttgtgga aaggacagct      540

tttaaataaa ggaaaacttt tgtgttatat ttctctgagg tcagccactc gtgctttttt      600

gcctatcaaa ctacctgaga aattagatgt tgaaacagtt atgagtattg atcatctgaa      660

acagaaaatc cctccagcac tgttttataa ggaaacatac ttaggtccaa atgaagtttt      720

gaagaatgga atgtattgca gcctttatga agttgtggaa aagacaagaa ttggaagtaa      780

catggagagt ttactgcaaa aactagacag agaaaaactt gttcttgtta aacctttggg      840

agaccgagga tacctttttc ttctctcccc ttatcagatg gttcctccat atgaatatca      900

gactgccaag tctcgagtcc tacatgcttt gtttctattt caagaaccta gaagcatagt      960

tacttcacaa aaaggttcaa ccaatgcagc accacaggag aggcatgaga gcatgccaga     1020

tgtattaaaa atagctcagt ttttacaatt ttctttgatt cagtgtcgaa aggaattcaa     1080

aaatataagc gccataaatt ttcattctgt tgttgaaaag tatgtaagtg aattttttaa     1140

gcgaggtttt ggttcaggta aacgagagtt tattatgttt ccatatgatt cacgattaga     1200

tgataaaaaa ttcttatact cagctcccag aaataaatcc catattgata cttgtttgca     1260

tgcctatatt tttcggcctg aagtgtatca gttacctatt tgtaaattaa aagaactatt     1320

tgaagaaaat agaaaacttc agcagtttag tccactttca gattatgaag gtcaagaaga     1380

agaaatgaat ggtacaaaaa tgaaatttgg aaaacgaaat aactcaagag gtgaagccat     1440

tatatctgga aagcaaagat catctcattc tttggattat gataaggata gagtcaaaga     1500

attgattaat ttaattcagt gtaggaaaaa gagtgtgggt ggggactcag acacagaaga     1560

tatgagaagc aaaactgtct tgaagaggaa gcttgaggat ctacctgaaa atatgagaaa     1620

gctcgccaaa accagtaatt tatctgaaaa ttgccatctg tatgaagagt ctccacagcc     1680

tattggctca cttggacatg atgctgactt gaggcggcag cagcaggata cctgtaactc     1740

cggcattgct gacatccata ggctgtttaa ttggttatca gaaacactag caaatgcgcg     1800

ccattctgat gcatctctga cagacacagt caacaaagcc ttaggattga gcactgatga     1860

tgcctatgaa gagctgaggc aaaaacatga gtatgagttg aactctaccc cagataagaa     1920

agactatgag cagcctactt gtgcaaaagt tgaaaatgca cagtttaagg gtactcagag     1980

cttattacta gaagttgatg caacatctaa gtattctgtt gctatttcta ccagcgaagt     2040

gggcactgac cataagctac atttgaaaga agatccaaat ttaattagcg tgaataattt     2100

tgaagattgc agtttgtgtc ccagtgttcc cattgaacat ggatttcgta gacaacagtc     2160

taagtcaaat aatgttgaag agactgaaat acattggaaa ctgattccaa ttacaggagg     2220

gaatgcaaga agcccagaag accagctggg gaaacatggt gagaaacaaa caccagacac     2280

actaaagggc accactgagg atgacgtgtt gacaggtcag gtggaggagc agtgtgtgcc     2340

agcagcagag gcagagccgc ctgcagtgag cgaaaccaca gagaggacag tgttaggaga     2400

gtacaatctc ttttctagga agatagaaga gattttgaag caaaagaatg tttcatatgt     2460

cagtacagtt tccacaccta tcttttcaac acaagagaag atgaaacggc tttccgagtt     2520

catatattct aagacttcca aagctggtgt gcaggagttt gtagatggtt tgcatgagaa     2580

gctaaatact attattatta aagcatcagc caagggtggg aatttgccac cagtcagtcc     2640

taacgattct ggtgctaaga tagcatcgaa tcctctggaa aggcatgtca taccagtttc     2700

ctcaagtgac ttcaacaata aacatctcct tgagccactg tgtagtgatc ctttgaaaga     2760

taccaactct gatgagcagc attccacttc ggctttaact gaagtagaaa tgaaccagcc     2820

tcaacatgcc acagagttaa tggtgacttc tgatcatatt gtacctggtg atatggcccg     2880

ggaaccagta gaagaaacaa caaaatcccc cagtgatgta aacatttctg ctcaaccagc     2940

tctttcaaat tttataagcc agttagaacc tgaagtattt aatagtttgg ttaaaatcat     3000

gaaagacgtc cagaaaaata ctgtgaaatt ttatattcat gaagaagaag agagtgtgct     3060

ctgtaaagaa ataaaggaat atcttatcaa attaggcaat acagaatgtc atcctgaaca     3120

gtttttggaa agaagatcaa aattagataa actattgatt attattcaaa atgaagacat     3180

tgcaggtttc attcacaaga tacctggctt ggtgacttta aagaagctcc cctgtgttag     3240

ttttgctggt gttgatagcc tggatgatgt taaaaatcat acatacaatg aattatttgt     3300

atctggaggt tttatcgtat ctgatgaatc aattctaaac ccagaggttg tcacagttga     3360

gaaccttaaa aattttttga cattccttga ggaacttagt actccagaag gaaaatggca     3420

atggaaagtc cactgtaaat ttcagaagaa actaaaggaa ctaggcagat tgaatgctaa     3480

agctctaagt ctgttgacgc ttctgaatgt ctatcagaag aaacatctgg ttgaaatttt     3540

gtcataccac aattgtgatt cacaaactcg aaatgctcca gaattggatt gccttatcag     3600

acttcaggct cagaacatac agcaacgaca catagtcttt ttaacagaga agaacatcaa     3660

gatgctttcc agttatacag ataatggaat agtggttgca actgctgaag acttcatgca     3720

aaactttaaa aatcttgtgg gctatcacaa ttcaatcaca gaagaaaacc ttccacagct     3780

tggtgctaat gagaatcttg agtcgcagtc agctctttta gaaaacgatg aaaaggatga     3840

agaggatatg tctctggatt caggggatga aatctcacat atagaagtat gcagcaattt     3900

tcattcagaa atatgggaga aagagaccaa aggatcacgt ggaacagatc aaaaaaagaa     3960

tactcaaatt gagttgcaat cgtctcctga tgtgcaaaac agtttattag aagataagac     4020

ttaccttgat tctgaagaga gaacttctat tgatatagta tgctctgaag gagagaacag     4080

caattcaaca gaacaagatt catatagtaa ctttcaggtt tatcatagtc aattaaatat     4140

gtcccatcag tttagtcatt ttaatgttct cactcatcag acatttttgg ggacaccata     4200

tgccctttca tcaagtcagt ctcaagaaaa tgagaattac ttcttatctg cttatactga     4260

aagcttggat agagataaat ctccacctcc cttaagttgg gggaaaagtg attcttccag     4320

gccatattca caagagaaat aactgtagta actttttttt taagagattg ttgtggactt     4380

tgtttattaa caatttatat ttcattctct aaacaaaagg ttcttgttct ttctcaaatg     4440

ttttttcttt tatttaaatc atgatggcct gtaacagttg aagcatctaa aaattgaaat     4500

aaatatatat ttttaacata tattgtactt gaattatctc atgttggcac ttctaagttt     4560

tactttttgt atgttacctg tacttaggct tcaaattgaa gcctgtttta tgtgtaaaat     4620

cagatgcttg caggaggacg gtaaacagca aaggctttac ttctttttct ctaatgtcac     4680

ctgatataaa gtacttttgt tgaagtgaat tattttgatg taggcttttg tatactgtgt     4740

ttacacaggt ataagtcagt aatagcagtg ttaatattta caggattttg gctcgatacc     4800

tcaagattta tctaacagtg cagtttcatt tagataataa actatgtaca taggacacat     4860

tttttatctc taggcttagt catgtaaaaa ctgcctattg ctaaaattct ggtaactttt     4920

tgagagtatt ggataatttt cagtacctgc gcaatccttg atttaatgaa attaaatttt     4980

ttatttcaaa agataggctt ctgtttatca aaggcgttga acaatttgat ttttaaatta     5040

gttttagcaa aatggaagta taatgggaat atatttttga ggtggtctta gtagtaatta     5100

ccatttgttg aacacattaa tgctatacta gacagataca gtggagatag ctttcaaacc     5160

cgtatctatt cctaactact gcctctaata ctaattacta acttgttact aatgctaact     5220

tttaaaaatg tttttgaaaa ttgcaatttc tacaaataaa tgtcatagtg caaataaatg     5280

tcaggattta gagaaggagc ctaaactgaa tttgtgttat ttcagtaaaa gttatggagt     5340

tatgggtcta gacgtgttaa taagttagac agaactttgg cactttagaa caaatgcatg     5400

agtggtattt cagttcctaa gttacataaa aagtgtgaaa gaacactgtg aggtcccagc     5460

aacgccagac tatattaagg taagtagaaa gtgtttttat agggcttcaa tacccaggtg     5520

gtgacagagc agaagaaccg gttttttttt tttttttttt actactaagc ttttacaaaa     5580

gaagtatctg ttttattgta tagaacaagt acagcatttt actacatagt atacaagttt     5640

ttaatgagca tttaaaaaaa taagtaaatc taggctattt gaaaaataca gttgagccag     5700

tgagcacatt ttataatttg gaagacacaa atcaaatgtg aaggatttga ttttctacat     5760

ttaaaatgaa gaaccaaaac tctcttcttg attttcagct aaaggcagga gactactttc     5820

caactccttt tgcttctgga gaaggccctg aaatcacatt gatatatgtt tgttagtaaa     5880

atgtgcacac ctgacttgca atgttgtgtt aaactagaat tatattcact tggaaaacat     5940

atcgcttagg ataaaatttt gtcattcaaa aattttttca gaaatgcttg tactagacca     6000

cctcatttgg atatatagct atcacatttg taagattctg tttttagcat aaaaatcaat     6060

agggatgaaa attttcttag aactcaagac tccataacta tgggggtaaa tgaagtcatc     6120

ccttctcccc cagtccaccc ccaagtgctc ttagatactg aaggagtctc ccttaacata     6180

cagtgttttt tttttgttgt tgttgttttg tttttttttg gagatggagt ctcgctctgt     6240

cgcccaagct ggagtacagt ggtgcaatct cactgcaagc tctgcctccc aggttcacac     6300

cattctcctg cctcaacctc ccgaatggct gggactacag gcacccacca ccacgcctgg     6360

ctaactaact aactaacttt ttgtattttt agtagagaca gggtttcact gtgttagcca     6420

ggatggtctt gatctcctga cctcatgatc tgcctgcctc agcctcccaa agtgctggga     6480

ttacaggctt gagccactgc tcctggccaa catccagtat tttatcttga ctgtcctaac     6540

cttaccttag atgctaacag aagggtcctg ctgaaataac actgggtgct atattgatgg     6600

gtaaatgtgt acatcctatt ccttcctctt tatctcacaa tttttgtctc cactaagcaa     6660

gaagtaaact aacacttcgt cactctaaag aaataactta tgtaaaactc ttagtaaccc     6720

tgtttgtctt caaatgagta aatagaccaa agtgggggga caattttcta gttctgtaga     6780

gggaaaaaca tctgagtcaa cattttgaaa tgcagagggt attggtacat gacgacatgg     6840

aaaagggcac ttttaaacac agcttactct tcctcaagta cagagagtat atagtgaatc     6900

aaaactaact acagccattc tttttaaagc ccaagggatg gagcaaaggt gtaaggatgt     6960

tacctgtttg ttttaatcag agagcaaaaa gaagtcacaa tagtttggga gaaaaagtag     7020

tatggtgagt aaggttatgc gtataatttc atactgaatt tattactatt tgggatgtac     7080

gtcaatgttc taacaaacac tgccaacacg tcaatttttt aaaaagcgtg ggccacattg     7140

ctaagaattt gttaaagcat aactgtattt tttgttttag ggccttattg atgttttgcc     7200

gttccaatgt atgcattttt ttactcaata aacttgtctt aatttta                   7247


<210>  1573
<211>  926
<212>  DNA
<213>  homo sapiens

<400>  1573
gctcgtgctg tgacgcaagc ctcgcctcgc cccgcgccgc gcgcgttgcc agggtgatca       60

ggtgactccc ggttcgcggc gctgggagcg gccgtgacgt caggcgcccg gctgctcctc      120

acttgctctg agacaggtgc ggcaagtcta ctgcgggctg gtccgggctc ctcaggttca      180

gacccgaccg ttatccagtc ggttcgtgga gaggagaggt gcactttaca ggtccccgat      240

gaaccaagag aaccctccac catatccagg ccctggtcca acggccccat acccacctta      300

tccaccacaa ccaatgggtc caggacctat ggggggaccc tacccacctc ctcaagggta      360

cccctaccaa ggatacccac agtacggctg gcagggtgga cctcaggagc ctcctaaaac      420

cacagtgtat gtggtagaag accaaagaag agatgagcta ggaccatcca cctgcctcac      480

agcctgctgg acggctctct gttgctgctg tctctgggac atgctcacct gaccagacca      540

gcccagccgt cctgtcctgc cagctctgct gccacctctg acaggtgtgc ctgcccccat      600

ctcttctgat tgctgttaac aaatgactag ctttgcacag acacctctac cttcagcact      660

atgggattct agattaatgg gggttgctac tgtttaattc agtgacttga tctttttaat      720

gtccaaaatc catttcttat tgatctttaa agatgtgcta aatgactttt ttggccaaag      780

gcttagttgt gaaaaatata atttttaaat tatacattca aggtagtggc caaatgtaac      840

acatcaatca tggaatgatt tctctgctaa cagccgcctg tatgtttcaa taaatttgtc      900

caaagctcaa aaaaaaaaaa aaaaaa                                           926


<210>  1574
<211>  926
<212>  DNA
<213>  homo sapiens

<400>  1574
gctcgtgctg tgacgcaagc ctcgcctcgc cccgcgccgc gcgcgttgcc agggtgatca       60

ggtgactccc ggttcgcggc gctgggagcg gccgtgacgt caggcgcccg gctgctcctc      120

acttgctctg agacaggtgc ggcaagtcta ctgcgggctg gtccgggctc ctcaggttca      180

gacccgaccg ttatccagtc ggttcgtgga gaggagaggt gcactttaca ggtccccgat      240

gaaccaagag aaccctccac catatccagg ccctggtcca acggccccat acccacctta      300

tccaccacaa ccaatgggtc caggacctat ggggggaccc tacccacctc ctcaagggta      360

cccctaccaa ggatacccac agtacggctg gcagggtgga cctcaggagc ctcctaaaac      420

cacagtgtat gtggtagaag accaaagaag agatgagcta ggaccatcca cctgcctcac      480

agcctgctgg acggctctct gttgctgctg tctctgggac atgctcacct gaccagacca      540

gcccagccgt cctgtcctgc cagctctgct gccacctctg acaggtgtgc ctgcccccat      600

ctcttctgat tgctgttaac aaatgactag ctttgcacag acacctctac cttcagcact      660

atgggattct agattaatgg gggttgctac tgtttaattc agtgacttga tctttttaat      720

gtccaaaatc catttcttat tgatctttaa agatgtgcta aatgactttt ttggccaaag      780

gcttagttgt gaaaaatata atttttaaat tatacattca aggtagtggc caaatgtaac      840

acatcaatca tggaatgatt tctctgctaa cagccgcctg tatgtttcaa taaatttgtc      900

caaagctcaa aaaaaaaaaa aaaaaa                                           926


<210>  1575
<211>  1280
<212>  DNA
<213>  homo sapiens

<400>  1575
aatacctgcg ttctgtagcg ctagttctct tcaagatttg cttagtgtca tttcatttcg       60

gtttcttttc tcgccatgtt tttctgtcgg aattacggtt cgttttggtt ctatgtactc      120

tctaaaatgt tatcgttttt catttgtcta ctaattttcg tgcatttgtt actactgagt      180

ttcttaatat ctgactggcc tccgcccacg ggctctgcag agcataaata ctcaggctga      240

tggtagtgca gagactctcc ctccttgatc agcgcaaacg ttggtctgag gcttgaggga      300

tggagcaaca ttttcttggc tgtgtgaagc gggcttggga ttccgcagag gtggcgccag      360

agccccagcc tccacctatt gtgagttcag aagatcgtgg gccgtggcct cttcctttgt      420

atccagtact aggagagtac tcactggaca gctgtgattt gggactgctt tccagccctt      480

gctggcggct gcccggagtc tactggcaaa acggactctc tcctggagtc cagagcacct      540

tggaaccaag tacagcgaag cccactgagt tcagttggcc ggggacacag aagcagcaag      600

aggcacccgt agaagaggtg gggcaggcag aggaacccga cagactcagg ctccagcagc      660

ttccctggag cagtcctctc catccctggg acagacagca ggacaccgag gtctgtgaca      720

gcgggtgcct tttggaacgc cgccatcctc ctgccctcca gccgtggcgc cacctcccgg      780

gtttctcaga ctgcctggag tggattcttc gcgttggttt tgccgcgttc tctgtactct      840

gggcgtgctg ttcacggatc tgtggagcta agcagcctta gatagcagca gaaggctttt      900

tggattctcc tccttgaaaa gattctcagt taccaaacgt ctccacctag aaaataaaaa      960

tacattaaga tgtgctttca ttgctggttg tcagttttta aattctcttt ttcccttatg     1020

tttctttctt gtttcgcgtc gcttattact ttcagtttcc ttgtatttta aatatttgta     1080

tttatttcat taaatatttc attcgtatct gttttcactt tgagaaatct attttacgat     1140

tgtagaattc ttagagtttt tggcaaattt aaaatttgtt tttttccatt gtattttaaa     1200

atcttattcc tactattttt ctaattattg ctttttaaat gtattgtttg tttacattta     1260

attttaaaaa aaaaaaaaaa                                                 1280


<210>  1576
<211>  2619
<212>  DNA
<213>  homo sapiens

<400>  1576
aggccctggg acctcccggt cccttgcctg cttccggctt tcgctcgctt ccatatccgc       60

tcctctagtc gccctccgct ggccccgcct tcgtccccgg aagattgggt cttctggcga      120

gccactgttt gccgtttgat cgggcaccaa ataaagtttc tttattcaaa agcacttttt      180

ttttaaagcc acaccacccc cattctcagc tcctccttcg cggcggtacc gcctctgttt      240

ctgcggcgat tgaacagccg agctttgcgg ccgggatcgc ggaaagtgat ggctgtcgtc      300

ccggcgtctc tctcaggaca ggacgtggga tcatttgcat atcttacaat taaagacaga      360

ataccacaga tcttaactaa ggttattgat acattgcatc gacataaaag tgaatttttt      420

gagaaacacg gagaggaagg cgtggaagct gaaaagaaag ctatctctct cctttctaaa      480

ttacggaatg aattgcaaac agataaacca tttatcccct tggttgagaa atttgttgat      540

actgatatat ggaatcagta cctagaatat caacagagtc ttttaaatga aagtgatgga      600

aaatcaagat ggttctactc accgtggttg ttggtagaat gttacatgta tcgaagaatt      660

catgaagcaa ttatccagag tccaccaatc gattactttg atgtatttaa agaatcaaaa      720

gagcaaaatt tctatgggtc acaggaatcc atcattgctt tatgtactca cctgcaacaa      780

ttgataagaa ctattgaaga cctagatgaa aatcagctga aagatgagtt ttttaaactt      840

ctgcagattt cactgtgggg aaataagtgt gatctgtctc tctcaggtgg agaaagtagt      900

tctcagaata ccaatgtact aaattcattg gaagacctaa aacctttcat tttattgaat      960

gatatggaac atctttggtc attgcttagc aattgcaaga aaacaagaga aaaagcttct     1020

gctactagag tgtatattgt tctcgataat tctggatttg agcttgttac agatttaata     1080

ttagccgact tcttgttgtc ctctgaactg gctactgagg ttcattttta tggaaaaaca     1140

attccatggt ttgtttctga tactactata catgatttta attggttaat tgaacaggta     1200

aaacacagta atcataagtg gatgtccaag tgtggggctg actgggaaga gtatattaaa     1260

atgggtaaat gggtttacca caatcatata ttttggactc tgcctcatga gtactgtgca     1320

atgcctcagg ttgcacctga cttatatgct gaactacaga aggcacattt aattttattc     1380

aagggtgatt tgaattacag gaagttgaca ggtgacagaa aatgggagtt ttctgttcca     1440

tttcatcagg ctctgaatgg cttccatcct gcaccactct gtaccataag aacattaaaa     1500

gctgaaattc aggttggtct gcagcctggg caaggggaac agctcctggc ctctgagccc     1560

agctggtgga ccactggaaa atatggaata tttcagtacg atggtcccct ttgacttgat     1620

ttaggagctc tcagttgcat agaaagatct ggtgagcacc ttttcatccc cagaaaagga     1680

gcacgtgaat tgagtcgcct ggcggctctg tacgcgctca gggaagctta gcttcttggt     1740

gcccatctac gtgcactgga tgatttttct tttgaacatt ttgccccact acactgtttt     1800

ggggatagct gggttaagca agttaaagat atttacattt atattggaat tttagcaact     1860

ttttttcagg ttaaatatat aatttcaagt gcttttaatg aacttatttt taattggcta     1920

gggagcaaaa aataagtgag ttctgctttt agttagttaa ccttgttctt ttcttaaata     1980

gtacactgca tggtatttaa tattccagga agcatgggat tttattttgc ttgattttgg     2040

gcacatgaaa taatagctct aggaaaatgc gcatcttaat gactctttgt aaagagaggc     2100

atttcttaca actgtgatgt ttgcttacat aaaagttacc tcataagtta attctaactt     2160

ttattcttga attttatttc atttcaatag cttgtttcat ttgcacgcct ttgtattttg     2220

attgacctgt agaatggatg ttaggaaact caaaattgaa cacagtgaaa caaatggtat     2280

ttgaagaaat gtaatatctt ttatattcta tttatgatat ccataatcaa atgagattat     2340

tttaccacat aaatgtttta aatatcagat ttttagtttg cagttttagg aaaatgcttt     2400

agatagaaaa ggttcttatg cattgaattt ggagtactac caacaatgaa tgaatttatt     2460

ttttatattc ttacacattt tattggtcat tgtcacagat agtaaatact aaaaatttca     2520

ggtcagtttg ttttgaaact gaaattggaa ataaatctgg aaatgttttg ttgcactaaa     2580

ataataaaat gaattgtact gaaaaaaaaa aaaaaaaaa                            2619


<210>  1577
<211>  789
<212>  DNA
<213>  homo sapiens

<400>  1577
gagaagagca ctgattggct gaggcagaaa agtgcccctg cctcggcgct ttcggttttg       60

gctgggatca tccgcggcgg ccgggctcgt ggggcgcctg gagtgagggt tctggttccc      120

gccggcgagg attgttaaaa tgagtcttcg gaagcaaacc cctagtgact tcttaaagca      180

aatcatcgga cgaccagttg tggtaaaatt aaattctgga gtggattatc gaggggtcct      240

ggcttgcctg gatggctaca tgaatatagc cctggagcag acagaagaat atgtaaatgg      300

acaactgaag aataagtatg gggatgcatt tatccgagga aacaatgtgt tgtacatcag      360

tacacagaag agacggatgt gaagacacca agagagcaac gcttttcata gttggatata      420

tttttttatg aattttttct aatttttgct tcttttgtga tacaatttgt cctcttttta      480

taatagttgg tgatttttca ctgacatgtg agtaagataa atgtatacaa ttgtggattt      540

aattgtgaaa tgttctttca cttgtaagtt tcagtcattt tcttttacct cgttgtcagt      600

gtacagaatg ctaaaataat taaaaaaaga caaaatatac ctcttcctac aagattattt      660

aacttaagtt tcgagaagtg tcatttcatt tgacttgctt ttcttatcca gctaaaatga      720

tgcatatatt ttatatattg tatggacata taattaaaac attttggagg aatcctcctt      780

tattgcaaa                                                              789


<210>  1578
<211>  789
<212>  DNA
<213>  homo sapiens

<400>  1578
gagaagagca ctgattggct gaggcagaaa agtgcccctg cctcggcgct ttcggttttg       60

gctgggatca tccgcggcgg ccgggctcgt ggggcgcctg gagtgagggt tctggttccc      120

gccggcgagg attgttaaaa tgagtcttcg gaagcaaacc cctagtgact tcttaaagca      180

aatcatcgga cgaccagttg tggtaaaatt aaattctgga gtggattatc gaggggtcct      240

ggcttgcctg gatggctaca tgaatatagc cctggagcag acagaagaat atgtaaatgg      300

acaactgaag aataagtatg gggatgcatt tatccgagga aacaatgtgt tgtacatcag      360

tacacagaag agacggatgt gaagacacca agagagcaac gcttttcata gttggatata      420

tttttttatg aattttttct aatttttgct tcttttgtga tacaatttgt cctcttttta      480

taatagttgg tgatttttca ctgacatgtg agtaagataa atgtatacaa ttgtggattt      540

aattgtgaaa tgttctttca cttgtaagtt tcagtcattt tcttttacct cgttgtcagt      600

gtacagaatg ctaaaataat taaaaaaaga caaaatatac ctcttcctac aagattattt      660

aacttaagtt tcgagaagtg tcatttcatt tgacttgctt ttcttatcca gctaaaatga      720

tgcatatatt ttatatattg tatggacata taattaaaac attttggagg aatcctcctt      780

tattgcaaa                                                              789


<210>  1579
<211>  1687
<212>  DNA
<213>  homo sapiens

<400>  1579
gactcccgcc cgcatctcgg ggtgggaagg gttcaggaaa cacagaccag cttatcttaa       60

ggaagcctgg tcgggaatct ttcaaaaaca catctgttac aagggggaaa gacacctcca      120

ggacaacagt gatttgcctc agcggggcaa aggccaggcc tgacggaaga gcccagcctt      180

cgccgagggc cgcagggagc cagagactcg agcctgcggt tccagccccg ccgcggttcc      240

ggccccgccg cgatcccgag gcctgcgcat gctcggtgct gcgcggggct ccctccttac      300

cgcaggagct cctcatcgag aaacccaggt tggtgtcttt tccacgtggt agaagctggc      360

taacctccac ttccacattc cagcccaagg gaaagtccaa ggtattgttg cagcatctgg      420

cagtgagact gaggatgagg acagcatgga cattcccttg gacctttctt catccgctgg      480

ctcaggcaag agaaggagaa ggggcaacct acccaaggag tctgtgcaga ttcttcggga      540

ttggctgtat gagcaccgtt acaatgccta tccttcagag caagaaaaag cgttgctgtc      600

ccagcaaaca cacctgtcta cgctacaggt ctgtaactgg ttcatcaacg cccgccgcag      660

gctcctccct gacatgctga gaaaggatgg caaagatcca aatcagttca caatttcccg      720

ccgtggggcc aagatttctg aaacgagctc tgtggagtcc gtgatgggca tcaaaaactt      780

catgccagct ctagaggaga ccccatttca ttcctgtaca gctgggccaa acccaaccct      840

agggaggcca ctgtctccta agccgtcatc cccgggatca gttttggctc gtccatcagt      900

gatctgccat accactgtga ctgcattgaa agatgtccct ttctctctct gccagtcggt      960

cggtgtggga caaaacacag atatacagca gatagcggcc aaaaacttca cagacacctc     1020

tctcatgtac ccagaggaca cttgtaaatc tggaccaagt acgaatacac agagtggtct     1080

tttcaacact cctcccccta ctccaccgga cctcaaccag gacttcagtg gatttcagct     1140

tctagtggat gttgcactca aacgggctgc agagatggag cttcaggcaa aacttacagc     1200

ttaacccatt ttcaagcaaa acagttctca gaaatgtcat gattgccggg gtgaaggcaa     1260

gagatgaatt gcattatttt atatattttt tattaatatt tgcacatggg attgctaaaa     1320

cagcttcctg ttactgagat gtcttcaatg gaatacagtc attccaagaa ctataaactt     1380

aaagctactg tagaaacaaa gggttttctt ttttaaatgt ttcttggtag attattcata     1440

atgtgagatg gttcccaata tcatgtgatt ttttttttcc tccccttccc tttttttgtt     1500

attttttcag actgtgcaat acttagagaa cctatagcat cttctcattc ccatgtggaa     1560

caggatgccc acatactgtc taattaataa attttccatt ttttttcaaa caagtatgaa     1620

tctagttggt tgatgccttt tttttcatga cataataaag tattttcttt aaaaaaaaaa     1680

aaaaaaa                                                               1687


<210>  1580
<211>  1947
<212>  DNA
<213>  homo sapiens

<400>  1580
gcgagagttc ccaagcggta ggcggcggcg ccgggagaga agcgccgcct agctgcgctt       60

ccgcaaagat ggcggcggct gcgggtagct gcgcgcgggt ggcggcctgg ggcggaaaac      120

tgcgacgggg gctcgctgtc agccgacagg ctgtgcggag tcccggcccc ttggcagcgg      180

cagtggccgg cgcggccctg gcaggagcag gagcggcctg gcaccacagc cgcgtcagtg      240

ttgcggcgcg ggatggcagt tttacagtct ccgcacagaa aaatgttgaa catggaataa      300

tatatattgg gaaaccgtct cttcgtaagc agcgcttcat gcagttttct tcactcgaac      360

atgaaggaga atattatatg acaccacgag acttcctctt ctcagtgatg tttgagcaaa      420

tggaacgtaa aacttcagtc aagaagctga caaaaaagga catcgaggat acactgtcag      480

ggatccaaac agctggctgt ggatcaactt ttttcagaga ccttggcgat aaagggctaa      540

tttcatatac cgagtatctt ttcttgctta caatcctcac taaaccccat tctggatttc      600

atgttgcttt taaaatgctg gatacagatg gtaatgagat gattgaaaaa agggaatttt      660

ttaagctgca gaagatcata agtaaacaag atgacttgat gacagtgaaa actaatgaaa      720

ctggatatca ggaagcaata gtgaaagaac ctgaaattaa cacaactctt cagatgcgtt      780

tctttggaaa aagaggacaa agaaaacttc attataaaga atttcgaaga tttatggaaa      840

atttacaaac agagattcaa gaaatggaat tccttcagtt ttctaaaggt ttgagtttca      900

tgagaaaaga agactttgca gagtggctac tttttttcac taacactgaa aataaagata      960

tttattggaa aaatgtgaga gagaagttgt cagcaggaga gagcattagt ttggatgaat     1020

tcaagtcatt ttgccatttt acaacccact tggaagactt tgctattgcc atgcagatgt     1080

tcagtttagc tcatcgtcct gtcagactag cggagtttaa gagagctgtg aaagtagcaa     1140

caggacaaga actctcaaac aatattttgg acactgtctt taagatcttt gatttggatg     1200

gtgatgaatg tcttagtcat gaagagtttc ttggggtgtt aaaaaacaga atgcatcgag     1260

gtttatgggt accacaacat cagagtatac aagaatactg gaagtgtgtg aagaaagaaa     1320

gcattaaagg agtaaaagaa gtctggaaac aagctggaaa aggtcttttt taataaaaga     1380

tataatagta tggcaattat attgttccaa atgtcaaaat ttgtgatttt ttagaagtac     1440

ttgctattta tcttcttaag tcttcattga tattctgtgt gaaataagca tgtcttgtac     1500

ttgctttctg attcataatt ttattaaaga acttagtaga aagaaaagta agtataaaaa     1560

tagatattgg attctgtcag aaggcctaga tttgaaataa tgttttgtac ttcggtaaga     1620

tggaaaactt agtgattcac tgatttctta gacactctaa tatgatatgc tttctggaag     1680

gataaaacaa atacatatgg gaaaaagtac ttgagaccaa ggccagcatc aattccagac     1740

atcttcatgt tcctaatagg ctaaatgaag ttaaaaactt atttcagatt tttctcatct     1800

gtaccttata tctcataaat ttattgcata ttttatgtca gtagcttagc tgtttattgt     1860

ctttaaaata acatgtaaac ttcaatgttc tatctggaag cagaataaaa tatttacata     1920

gatacaaaaa ataaaaaaaa aaaaaaa                                         1947


<210>  1581
<211>  5149
<212>  DNA
<213>  homo sapiens

<400>  1581
gggggcgggg cggggcgcag ctccgacttc ggacatggcg cacgctggcg gtggcagcgg       60

tggcagcggt gccggcggcc ccgcgggccg ggggctgagc ggcgcccgct ggggtcgctc      120

gggctccgca ggccacgaga agctgccggt gcacgtagaa gacgccctca cctatctgga      180

ccaggtgaag atccgctttg gcagcgaccc tgccacctac aacggcttcc tggagatcat      240

gaaggagttc aaaagccaga gcatcgatac tcctggagtc atcagacgtg tctcgcagct      300

cttccacgag caccctgacc tcattgttgg attcaacgct tttcttcccc tcggatatag      360

aatagacatt cccaagaatg gcaagttaaa catacagtcg cctctgacaa gccaggagaa      420

ttcgcacaac cacggggacg gtgcagagga cttcaagcag caggtgccgt ataaagagga      480

caaaccccag gtgcccctgg agtccgattc cgtggaattc aacaacgcca tcagctatgt      540

gaataagatt aaaacccgct tcctagacca cccagaaatc tacaggtcat tcctggagat      600

cctgcacacg taccagaagg agcagctgaa cacgaggggc cggccattcc gaggcatgtc      660

tgaagaggag gtgttcaccg aggtggccaa cctcttccgg ggccaggagg acctgctctc      720

agagtttgga cagttcctgc ccgaagccaa gcggtctctg ttcacaggaa acgggccgtg      780

cgagatgcac agcgtgcaga agaacgagca cgacaagacc ccggagcaca gcaggaagcg      840

ctcccggccc tcgctcctcc gccccgtgtc tgcacccgcc aagaaaaaaa tgaaacttcg      900

tggtaccaaa gacctgtcca tcgctgcagt ggggaagtac gggactctgc aggaattttc      960

tttctttgac aaggtccgcc gggtgctgaa gagccaggag gtgtatgaaa acttcctccg     1020

ctgcatcgca ctcttcaacc aggagctggt gtctggctct gagctcctgc agctcgtcag     1080

cccatttctg gggaaatttc cagaactctt tgcacagttc aagtccttcc tgggggtaaa     1140

agagctgtcc ttcgcgccac ccatgagcga cagatccggg gacgggataa gccgggaaat     1200

tgattatgca tcctgcaagc gcataggatc cagctaccgg gcactcccca aaacctacca     1260

gcagcccaag tgcagtggga ggacagccat ctgcaaggag cttgaccatt ggacacttct     1320

ccagggttcg tggacagacg attactgcat gtccaagttc aagaatacct gctggattcc     1380

aggatatagt gcaggggtac tgaacgacac ctgggtctcc ttcccttcct ggtctgagga     1440

ctccacgttc gtcagctcca agaagacacc gtacgaggag cagcttcacc gctgtgagga     1500

cgagcgcttc gagttagacg ttgtcctgga gacgaacctg gccacaatcc gtgtgttgga     1560

aagtgtgcag aagaagctgt ctcggatggc gccggaagac caggagaagt tccggctgga     1620

cgactccctg ggaggcacgt cggaggtgat ccagcgccgt gccatttatc gcatctatgg     1680

cgacaaggcc ccggagatca tcgagagcct caagaagaac cctgtcaccg ctgtccccgt     1740

tgtcctgaaa agactgaagg ccaaggaaga ggagtggcgg gaggcccagc agggcttcaa     1800

caagatctgg cgggagcagt atgagaaggc gtacctcaag tcccttgacc accaggctgt     1860

gaacttcaag cagaacgaca ccaaggccct gcgctccaag agcttgctca acgagatcga     1920

gagcgtctac gacgagcacc aggagcagca ctcggagggc cgcagtgccc cctctagcga     1980

gccgcacctc atctttgtgt acgaggaccg gcagatcctg gaggacgcag cagcgctcat     2040

cagctactac gtgaagcggc agccggccat ccagaaggag gaccagggca ccatccacca     2100

gctgctgcac cagttcgtgc ccagcctctt cttctctcag cagctggacc tgggcgcctc     2160

cgaggagtca gctgatgagg accgggacag cccccagggg cagaccacag accccagtga     2220

gcggaagaag ccggcgccag gaccccacag tagcccccca gaggagaagg gggccttcgg     2280

ggatgccccg gccactgagc agccacccct gccgccccca gccccgcaca agcccctgga     2340

cgatgtctac agcctatttt ttgccaacaa caactggtac ttcttcctgc gcctgcacca     2400

gaccctgtgc tccaggctgc tgaagatcta ccgccaggcg cagaagcagc ttctggagta     2460

tcggaccgag aaggagcggg agaagctgct gtgtgagggc cgcagggaga agggcagcga     2520

ccccgccatg gagctgcggc tgaagcagcc cagtgaagtg gagctggagg agtactaccc     2580

ggccttcctg gacatggtgc ggagcctgct ggagggcagc atcgacccca cgcagtacga     2640

ggacacccta cgcgagatgt tcaccatcca tgcctacgtg ggcttcacca tggacaagct     2700

ggtgcagaac attgcgcggc agctgcacca cctcgtgagc gatgacgtct gcctgaaggt     2760

ggtggagctc tacctgaacg agaagaagcg gggtgccgct ggtgggaacc tgtcctcccg     2820

ctgcgtccgc gctgctaggg agaccagcta ccagtggaag gctgagcgct gcatggccga     2880

cgagaactgc ttcaaggtga tgttcctgca gcgcaaaggg caggtgatca tgaccatcga     2940

gctcctggac accgaggagg cccagacgga ggaccctgtg gaggtccagc acctggctcg     3000

gtacgtggag cagtatgtgg ggaccgaggg cgcgtccagc tcgcccactg agggcttcct     3060

cctgaaacct gtgttcctgc agaggaacct caagaagttc cgccgccggt ggcagagcga     3120

gcaggcgcgg gccctgcgcg gtgaggccag gagctcctgg aagcggctgg tgggcgtgga     3180

gagcgcctgc gacgtggact gccgcttcaa gctcagcact cacaagatgg tgttcatcgt     3240

gaactccgag gactacatgt accgtcgcgg gaccctctgc cgggccaagc aggtgcagcc     3300

cctggtcctg ctccgccacc accagcactt tgaggagtgg cacagccgct ggctggagga     3360

caatgtgacg gtggaggcgg ctagcctggt gcaggactgg ctgatgggtg aggaggacga     3420

ggacatggta ccctgcaaga cgctgtgtga gacagtgcac gtgcacggcc tgcccgtgac     3480

ccgctaccgc gtgcagtaca gccgccgccc ggcctcgccc tgacccgccc tcatgggcac     3540

cgggcaggcg cctcacagag cacagacgtg ccctcggcct tggtcgtgtc ggggccgttt     3600

tcttgaacga cgtgagaggc atctcccagc ccctctgctg ccggacagcg cactccaggg     3660

caggacgccg cccccgtggc tcccggtctc ctgtgggcct gctgtgtgcc aaacctgagc     3720

tacctgcacc cgagccctgg ggctcagccc caccacaggg gcgggtggac gtgctggccg     3780

aggaacaagc aatcatgttt gcgtccccgt ccgtcacatg tgccaaatcc ctggcaggca     3840

gatggctcct gccccatatt cttgccgtgt cttggaaaag tcacaggtga cagccctcct     3900

gaggcccaca ctttggaggg ggtccatgtc caagagaccc tgacaaggaa ggagttgagc     3960

cctgggtagg cttgcttgaa aagtgagtcc ttccagaata ttctcagagc tgccagaaac     4020

atcatctgag ggtttgggca tcagctctgc ctggctggtg ttcaggccct cagtcacttt     4080

ggaagtgaga agaacccttc agccaaacct ttgggatccc attttgaagt ccagagctgg     4140

agcaggcggg cagtgccctg ggagaccccg ctctggataa gacacccaac cccaactcca     4200

gcagctggac tctgggccca caaggggagg gaccccagcc agtattccct cagagccggc     4260

acgaccctgc tgtggggcgg cgggcccagt cgtgttcctg cagtgggcac cctaggcgta     4320

tgtgtataca cgcacagata tttattcctt tcgcttttag tggttgttat ttctgtagca     4380

gccaagtcct gcggctccct ggggctgaga tctccctttg tggaactccg agagccgccc     4440

tgacagtccc agccgccacc caaggagccc catccgccca cccaccctgg gacccacgcg     4500

gccactccag ggatcattgt tgtccttttg tgaggggctg aggcgactgt cccatggagg     4560

catccaaggc tttctgtgcc aagaatccca agtgactggg gctggggacc acttctccag     4620

gcctctctcc ccgaccatga gagcccctgg ccctggcccc tgcacaccag taggcccaga     4680

ataaccgcca cccttgccat cctgcaacag ctggactcaa gtttccagga agtggagatg     4740

tgtttctaga agtttcctgt ggaacctgga ggctcctgat gcctttgact ccaggctggg     4800

cgattccgat gctgacccgt cctcctgggc tccccacccc cgctccccaa gtgtcacaca     4860

ggcactttgt acacatcctg gttttctaag aagggaactt gccatcaaga ttcctgtacc     4920

aggcccacgg ccgtctcggg cagagccacc tgggccccgg gtgcagccgg agaccccgcc     4980

gagcccctcc tcccagtatt cccatccccg catgcttcta gggagcgcct cttttccgtt     5040

cttgaggaat ttctgttctg gggcttgtcc ttcctttgca gctgttttga atgtagtttt     5100

ccttttctat ttatttgcac attaaagtta ataattgaat attgacatc                 5149


<210>  1582
<211>  10138
<212>  DNA
<213>  homo sapiens

<400>  1582
gcacgggctg gtctctgccc taatgcggcg gctggcggcg agaggcgctg caggggacgc       60

gggggaagtg gcggcgccgg cagcggacag ctcggacagc gcccagggcc ggagcccgag      120

cccttggagg ttgattgact tatgtgcaat ttgggacgct ggagtttacc ttccctccgc      180

agcctggaac agagcctcct ctggtgttgc aaggaagagg ctgaatgagg cagagaagct      240

gagtgctgtc caggaggccc agttaaagcg gctcgaggtg acaagacccc gagtgctggg      300

gagcagggag cagggccagg tgccgaggat ggccaggcag ccaccgccgc cctgggtcca      360

tgcagccttc ctcctctgcc tcctcagtct tggcggagcc atcgaaattc ctatggatct      420

gacgcagccg ccaaccatca ccaagcagtc agcgaaggat cacatcgtgg acccccgtga      480

taacatcctg attgagtgtg aagcaaaagg gaaccctgcc cccagcttcc actggacacg      540

aaacagcaga ttcttcaaca tcgccaagga cccccgggtg tccatgagga ggaggtctgg      600

gaccctggtg attgacttcc gcagtggcgg gcggccggag gaatatgagg gggaatatca      660

gtgcttcgcc cgcaacaaat ttggcacggc cctgtccaat aggatccgcc tgcaggtgtc      720

taaatctcct ctgtggccca aggaaaacct agaccctgtc gtggtccaag agggcgctcc      780

tttgacgctc cagtgcaacc ccccgcctgg acttccatcc ccggtcatct tctggatgag      840

cagctccatg gagcccatca cccaagacaa acgtgtctct cagggccata acggagacct      900

atacttctcc aacgtgatgc tgcaggacat gcagaccgac tacagttgta acgcccgctt      960

ccacttcacc cacaccatcc agcagaagaa ccctttcacc ctcaaggtcc tcaccaacca     1020

cccttataat gactcgtcct taagaaacca ccctgacatg tacagtgccc gaggagttgc     1080

agaaagaaca ccaagcttca tgtatcccca gggcaccgcg agcagccaga tggtgcttcg     1140

tggcatggac ctcctgctgg aatgcatcgc ctccggggtc ccaacaccag acatcgcatg     1200

gtacaagaaa ggtggggacc tcccatctga taaggccaag tttgagaact ttaataaggc     1260

cctgcgtatc acaaatgtct ctgaggaaga ctccggggag tatttctgcc tggcctccaa     1320

caagatgggc agcatccggc acacgatctc ggtgagagta aaggctgctc cctactggct     1380

ggacgaaccc aagaacctta ttctggctcc tggcgaggat gggagactgg tgtgtcgagc     1440

caatggaaac cccaaaccca ctgtccagtg gatggtgaat ggggaacctt tgcaatcggc     1500

accacctaac ccaaaccgtg aggtggccgg agacaccatc atcttccggg acacccagat     1560

cagcagcagg gctgtgtacc agtgcaacac ctccaacgag catggctacc tgctggccaa     1620

cgcctttgtc agtgtgctgg atgtgccgcc tcggatgctg tcgccccgga accagctcat     1680

tcgagtgatt ctttacaacc ggacgcggct ggactgccct ttctttgggt ctcccatccc     1740

cacactgcga tggtttaaga atgggcaagg aagcaacctg gatggtggca actaccatgt     1800

ttatgagaac ggcagtctgg aaattaagat gatccgcaaa gaggaccagg gcatctacac     1860

ctgtgtcgcc accaacatcc tgggcaaagc tgaaaaccaa gtccgcctgg aggtcaaaga     1920

ccccaccagg atctaccgga tgcccgagga ccaggtggcc agaaggggca ccacggtgca     1980

gctggagtgt cgggtgaagc acgacccctc cctgaaactc accgtctcct ggctgaagga     2040

tgacgagccg ctctatattg gaaacaggat gaagaaggaa gacgactccc tgaccatctt     2100

tggggtggca gagcgggacc agggcagtta cacgtgtgtc gccagcaccg agctagacca     2160

agacctggcc aaggcctacc tcaccgtgct aggacggcca gaccggcccc gggacctgga     2220

gctgaccgac ctggccgaga ggagcgtgcg gctgacctgg atccccgggg atgctaacaa     2280

cagccccatc acagactacg tcgtccagtt tgaagaagac cagttccaac ctggggtctg     2340

gcatgaccat tccaagtacc ccggcagcgt taactcagcc gtcctccggc tgtccccgta     2400

tgtcaactac cagttccgtg tcattgccat caacgaggtt gggagcagcc accccagcct     2460

cccatccgag cgctaccgaa ccagtggagc accccccgag tccaatcctg gtgacgtgaa     2520

gggagagggg accagaaaga acaacatgga gatcacgtgg acgcccatga atgccacctc     2580

ggcctttggc cccaacctgc gctacattgt caagtggagg cggagagaga ctcgagaggc     2640

ctggaacaac gtcacagtgt ggggctctcg ctacgtggtg gggcagaccc cagtctacgt     2700

gccctatgag atccgagtcc aggctgaaaa tgacttcggg aagggccctg agccagagtc     2760

cgtcatcggt tactccggag aagattatcc cagggctgcg cccactgaag ttaaagtccg     2820

agtcatgaac agcacagcca tcagccttca gtggaaccgc gtctactccg acacggtcca     2880

gggccagctc agagagtacc gagcctacta ctggagggag agcagcttgc tgaagaacct     2940

gtgggtgtct cagaagagac agcaagccag cttccctggt gaccgcctcc gtggcgtggt     3000

gtcccgcctc ttcccctaca gtaactacaa gctggagatg gttgtggtca atgggagagg     3060

tgatgggcct cgcagtgaga ccaaggagtt caccaccccg gaaggagtac ccagtgcccc     3120

taggcgtttc cgagtccggc agcccaacct ggagacaatc aacctggaat gggatcatcc     3180

tgagcatcca aatgggatca tgattggata cactctcaaa tatgtggcct ttaacgggac     3240

caaagtagga aagcagatag tggaaaactt ctctcccaat cagaccaagt tcacggtgca     3300

aagaacggac cccgtgtcac gctaccgctt taccctcagc gccaggacgc aggtgggctc     3360

tggggaagcc gtcacagagg agtcaccagc acccccgaat gaagcttaca ccaacaacca     3420

agcggacatc gccacccagg gctggttcat tgggcttatg tgcgccatcg ccctcctggt     3480

gctgatcctg ctcatcgtct gtttcatcaa gaggagtcgc ggcggcaagt acccagtacg     3540

agaaaagaag gatgttcccc ttggccctga agaccccaag gaagaggatg gctcatttga     3600

ctatagtgat gaggacaaca agcccctgca gggcagtcag acatctctgg acggcaccat     3660

caagcagcag gagagtgacg acagcctggt ggactatggc gagggtggcg agggtcagtt     3720

caatgaagac ggctccttca tcggccagta cacggtcaaa aaggacaagg aggaaacaga     3780

gggcaacgaa agctcagagg ccacgtcacc tgtcaatgct atctactctc tggcctaacg     3840

gagcccaccc aggcacagcc accactttgc aagtgggagg aggggagaag gggagacaaa     3900

accactgcag acctaccacg aagccaccac caccttcagt aacaagggta cgatatgggg     3960

gtctgccaag ctgtgaggac cagtagccac caagccaccc acaagccccc tcccaatgac     4020

cccccttcag ccccgggtgc caccagtgtg ggagagctgg agccgtggct gagctcagct     4080

ggagggagcc tggccccttg cccggtctcg cagccacccc gagcgttcca ccacactgtc     4140

cgcccttggc ctcggcacac gctcaccttt tctgttggtt acgggacttc tcattgtctt     4200

aatttcgctt tgtgcatctt cccctccaga cccaatgtct ctgttttctt ttccttttga     4260

aaaagagtcc ctggaaaaga aagaataagt ggattctccc ccaggagaat cctttttgca     4320

aagataggca aaaaggattg aatccatacc agaacacgta gacaggctgt aatattcaaa     4380

ccacctctgg gccaatgcat ttccaaagga tgcctttctc gccatatgcc tcccctggcc     4440

cccagcccct ctgcctcggc cttgtcagtt gctgagctgg gcttggctcc tttctggaaa     4500

atgacagtat ttttggcagg gagaaggtgc gcaggcctcc ttgctgctct ctggtttggt     4560

tgggaggtgt gtttacctct tgctcctcat tcctcccctg cccttttctc tggaatatct     4620

aagatgtgag ctgcattgac tctgaagacg tttgaggaac aggagtgggc actgatagaa     4680

aggacttcaa cgccagtgac tgtgtacctc cagcagaaga aaatcaggtg tctggtcttg     4740

ggggcactgt gctcacttct agagagaaga aaaaggctgg gtttggactt catgcctcct     4800

cactggtgaa acccaggatg tagatagagg gccacaccca ccctgtccag agtagagggc     4860

acctgtccac gtggccaggg cccatgctgc caccctcgag gagatggaac cctgtgatgc     4920

aaaagctttg ctggtgtgtt tggggcataa ggcactgctc cccttccatc tctagcagat     4980

atcatcttct cagccaattc tgtaggacac tgaggctctt gtttgacatg gtgtgtggat     5040

ggggacttgc cccaagactg agcaggtctg ccctttcatt ggggtgtata catatcaggg     5100

gaccctgagg tggcaccgta ctcagtgttg tgatgccccc acctagggag gactcaatgc     5160

tctttgtatg ccttatgcag cgctgatctg tccctggagt tcccaggttc ccagctcccc     5220

ccctgcaagc cttgaagcct ccagcaacgt ctatctccag gagagcaggg cagcctatgc     5280

aagtgttccg gcaggaccag aagtggccac tcaacacacg tcctcaccag tcaccccaaa     5340

tggagacact cgcagacctg cagttctcag accgaaggtg ctgccttcat cctccccacc     5400

taatgcattt ttgaaaccaa aggtacctag cctcagagac agagaaggag agggggagat     5460

cttgagtcta agaggaaccc tttagctgtt tctgcagctg aggtcagttt caggagggtg     5520

aagctgatcc ccaggaatgg atcagctgcc atgggcacag cctccgattt gagcctctcc     5580

ggctgccagc cagggggcct gggccagacc agggctctgt ccttccgtga ctttattaaa     5640

gcaacatttg ccacatgttt aagccgcaaa ggtattagca atgcttgcat cattaataat     5700

cattcagttg aaggtcaagc ccatagacac acactctctg ctggtaagaa accatagccc     5760

agaactgagc caataaggtt gtttgaacct gagagtgtgt aatggtcatt tgggccaagc     5820

ctcagctagg gctgctgcct ggacgcctga ggggcagctt atcacagtgc aaggggacag     5880

ggtaaacagc agggggtggg gtgtgagctt ggagggcccc tcccctggat ttcctccaac     5940

acctgcttgg atactaggcc cactgtccct gaagggaatg tcagggaagt gtgcctgtga     6000

gctgaattaa aggactggcc tttccagaaa acgctttgga tctgagcaga gtagtcagtt     6060

tctcagacac tcattccata ctgcaccgta catgccagcg tacccattgc accgaaagca     6120

ggcccttagg gcaggaaggg acgatgagca agtctgccac accacctggt gactgggaag     6180

ggctgcttct ctcgtaaggg tcttggggag aagtaagccc gcagcctgcc tctgcacctc     6240

gttccagtgt cctgccaggc tctgtactgt cctttgtgta tgaagaaaat gctgttagcc     6300

ctctctcagg ctgctgttct gtgggtgctg agagctgccc cccatcacca cgccatcaca     6360

cccctctgag cagaagcaaa tctgaggctg aagaattaag ttttccccaa gcaaggaagg     6420

caggtggtca gagagatcaa acgctgaggc gtggggattg caggattcag gaggcagccc     6480

ctttggggaa gaggagggtg cattttccat ggagcccatg tcagagtcca ctccagctca     6540

gcaggaaagt ggaattgccc agtactgcct gccagctggg tctcccaagc aactacccca     6600

agacatacca acagtgaagc caggacagca ccatgccatc ggcgctccag tctgtctggc     6660

tgggaggaaa gtgctgggca tcttacagta actctagaag ttcctttgac taggctgcaa     6720

tcccacctat atgctcagcc ctaagagctg tggtttcctg tgctctcatt tgtccattca     6780

ttcattcatt cattcattca gcaaataatc tgaaatccag tctgaactaa ggcctgagct     6840

gtggatacca tggcgcgtga gttagatgtg gtccctgccc tcatggggct gacagtccta     6900

aaatcaagtg ctaggacaca gtggccattg agctgggagc attcttccct ctaccgctta     6960

agccactgat ggctgcgagc ttgaagagag ggattctgag ggagagcttg gtccatctgg     7020

tcaccaaggc tgggcgggac agagcagtca agaaccacgg tgtggcttga gaaacagtcc     7080

tgcttcctga gcctctttgc tctgcctctt ggggcaagct ccttaacctg tctgtatttt     7140

tatgcctctg tctcccattc agttcctcct tgaatacctc tttctacaga gaggcacggg     7200

ctcccctgaa ggattgtcga ggccagggtt cgggaagtac actgccatcg gtcaggggac     7260

agctgcctcc caccttgcct gggtgatggt gaatgggact catcttttcc tgccttgctt     7320

ttgaggagat ggttgaattt aagctaacag gaaagccaaa ccagcaccct cctttgtgct     7380

ctgagaggtt ggagacatct ggtccacccc attgcccctg cccctggcaa gccctgaagt     7440

cgggagaggt gaccacaggt ctgaaaatca gccagtgcca acattgcttg ccctgcaagg     7500

tgcaactgag cccacatagc gcattcatag tttccctgac cacagccttg ggaagacggt     7560

ggaaacccga ggatgtgtgg gtttcccagc taacggacaa gctcccctgc cacacccagt     7620

gcccacgcat gctcacatac atacagcaga ccacaaccct gttgccaagc agtgcttcca     7680

agggatagcg atccagattc caacattgtc ttggagaggg ttagtccaca tccaagttgc     7740

gtgagataag atgcaaaggg ctctgtgtgg atgaggaacg caccttagag gagtgggaaa     7800

ggccaccagg gttgggccct gtttaggtaa ttcctgttgg cagcacctag agagagcatc     7860

tgagctgaag gagtgggaaa ctttgcccaa gcaatggcac gggcagcggg ctctttctgg     7920

cgccctgtgc tggagcaggg ccaagtctta gggcatcaca aacagcccat ttgatggagg     7980

gagcagggac atagcacatt tttgtctgtc tttgtgaggc tgctttgcta actctctgag     8040

gagaggaagc ctctcgggct ttccgtcggc tggggctagt gccagagaat cccttctcag     8100

tggccagcag gttcctggga ggccggcaca aggcaccgct ccccactcat gacaccttgg     8160

tgcagagtga cctcctgccc agtcaccact ccggccagcc ccagccaaac acacaaaagc     8220

ccatggttgc ggttgcatct acaccgttag ttggcaaagg atcctgcttg agctctgcgt     8280

ggtggccaag gagtagcatg gaggagggcc ctgattttaa aaaggaaaaa tagagaggcc     8340

tcaaaacaat gaaacaaaga gcttgatatg tcaagaggag accaaggccc tgggaggcat     8400

aggcaagccg ggcagagtca gaccagtgcc ctcccttgac catctcctag cattccttaa     8460

cctagacagg ggctacccca tgtgagtcca agccagactt tgtggctgtc cccagcctgc     8520

acagcccaag cccagggaag tgtcctttct ttcccttcct tactaataat gggccttcct     8580

gagacacatt cagagaagga tcagagagaa aggagaacca tccaggagag ccacaagcgt     8640

ccaccaaaca gtgtctcagg cctcacctga agctgctgtt cctcctatca gcacactagt     8700

attaaatggg tgttccataa tgaggagaat ggaaataggt acaaggcatc tagcttagga     8760

cagaatcgga tttcggcatg tgaaggaatc ccagagctga tctcattgaa atgatctatc     8820

gtacagacaa ggatatgcaa atccacagaa gtgaagggat ttttgctcaa gatcacatag     8880

ctggtaaact aaggtaaggt tagggcttga acttgggcct tctgactcct tgtccagtca     8940

gtgttctttc atctcaccac agctgcctcc tttgaaacag aggtattaag atctgtcctt     9000

ctggttcacc ctctcatacc tctttactgc gtctcccaca tcccccacat gcctcccaaa     9060

atgaaagaca aacaggattg tttctgagac caagatcagt ctgtctgtga tcagcctgtg     9120

tgtggttcac ccagtcatgc aattaagggc agatctgggc cagtggaata ggatagctga     9180

ttggtgtttg ttactgtgaa ccctagaccg taccccgtag aatggtgtct cttgctttgt     9240

aacacatcgg gccttcagtg tgctgtattc ctcagaagtg agggcatctc ggtccattct     9300

gcccatggcc acagggtgca gagaggcagc agggcccatg caagctgcca ccctgggatt     9360

tgctgggctg gagttcaaca gatgtaaaga cttcagtgaa gcaataaaca caaaactctg     9420

ggagaagata tccagaattt tgtacattac tctgtttctt tttcaaaaat gaggcagatc     9480

agatgcccct gagctgcccc tttttttctg attcccaact gcaatgtcct cagtcagtgt     9540

tgtccctctg cccggctccc cagctctttg ccaacctctt cacactcccc ttgagctgag     9600

catcagtcgc ctgtgacgtg gccaccttct gtcctgctcc cactcccgac ccatgctgga     9660

ccccggagga cctcctgccc cgcccccacc acacacccat atcccccacc attccaattt     9720

gttctttccc gtggggaatt ttttttccca gcgtctccat cccttcctac atatccacac     9780

acacacaaat tggtctgatc ttttttccat tggttaaaca tttaactcca tgccagacct     9840

tgttttaacc cctctcacat catgttcttt ccttttttgc gagttatttt gcattaacca     9900

actttgtcag tgacagatgc gtatctgagg gtgtcacaca cgaccttcag cagggaagac     9960

ttctgggcca tggagggccg tctaatacat ggacttataa actgactgca tgagcaatga    10020

aaaggccaaa ttattctgaa ttttttttga atcactgtaa aaaaactgat ttcttttgta    10080

tagagaacac taaacgtata ataaaagttg ttcaaaatgg aaaaaaaaaa aaaaaaaa      10138


<210>  1583
<211>  4724
<212>  DNA
<213>  homo sapiens

<400>  1583
ggcgggcgct cggcgactcg tccccggggc cccgcgcggg cccgggcagc aggggcgtga       60

tgtcacggca gggagggggc gcgggagccg ccgggccggc ggggaggcgg gggaggtgtt      120

ttccagcttt aaaaaggcag gaggcagagc gcggccctgc gtcagagcga gactcagagg      180

ctccgaactc gccggcggag tcgccgcgcc agatcccagc agcagggcgc gggcaccggg      240

gcgcgggcag ggctcggagc caccgcgcag gtcctagggc cgcggccggg ccccgccacg      300

cgcgcacacg cccctcgatg actttcctcc ggggcgcgcg gcgctgagcc cggggcgagg      360

gctgtcttcc cggagacccg accccggcag cgcggggcgg ccgcttctcc tgtgcctccg      420

cccgccgctc cactccccgc cgccgccgcg cggatgccaa gcaccagctt tccagtccct      480

tccaagtttc cacttggccc tgcggctgcg gtcttcggga gaggagaaac tttggggccc      540

gcgccgcgcg ccggcggcac catgaagtca gcggaggaag aacactatgg ctatgcatcc      600

tccaacgtca gccccgccct gccgctcccc acggcgcact ccaccctgcc ggccccgtgc      660

cacaaccttc agacctccac accgggcatc atcccgccgg cggatcaccc ctcggggtac      720

ggagcagctt tggacggtgg gcccgcgggc tacttcctct cctccggcca caccaggcct      780

gatggggccc ctgccctgga gagtcctcgc atcgagataa cctcgtgctt gggcctgtac      840

cacaacaata accagttttt ccacgatgtg gaggtggaag acgtcctccc tagctccaaa      900

cggtccccct ccacggccac gctgagtctg cccagcctgg aggcctacag agacccctcg      960

tgcctgagcc cggccagcag cctgtcctcc cggagctgca actcagaggc ctcctcctac     1020

gagtccaact actcgtaccc gtacgcgtcc ccccagacgt cgccatggca gtctccctgc     1080

gtgtctccca agaccacgga ccccgaggag ggctttcccc gcgggctggg ggcctgcaca     1140

ctgctgggtt ccccgcggca ctccccctcc acctcgcccc gcgccagcgt cactgaggag     1200

agctggctgg gtgcccgctc ctccagaccc gcgtcccctt gcaacaagag gaagtacagc     1260

ctcaacggcc ggcagccgcc ctactcaccc caccactcgc ccacgccgtc cccgcacggc     1320

tccccgcggg tcagcgtgac cgacgactcg tggttgggca acaccaccca gtacaccagc     1380

tcggccatcg tggccgccat caacgcgctg accaccgaca gcagcctgga cctgggagat     1440

ggcgtccctg tcaagtcccg caagaccacc ctggagcagc cgccctcagt ggcgctcaag     1500

gtggagcccg tcggggagga cctgggcagc cccccgcccc cggccgactt cgcgcccgaa     1560

gactactcct ctttccagca catcaggaag ggcggcttct gcgaccagta cctggcggtg     1620

ccgcagcacc cctaccagtg ggcgaagccc aagcccctgt cccctacgtc ctacatgagc     1680

ccgaccctgc ccgccctgga ctggcagctg ccgtcccact caggcccgta tgagcttcgg     1740

attgaggtgc agcccaagtc ccaccaccga gcccactacg agacggaggg cagccggggg     1800

gccgtgaagg cgtcggccgg aggacacccc atcgtgcagc tgcatggcta cttggagaat     1860

gagccgctga tgctgcagct tttcattggg acggcggacg accgcctgct gcgcccgcac     1920

gccttctacc aggtgcaccg catcacaggg aagaccgtgt ccaccaccag ccacgaggcc     1980

atcctctcca acaccaaagt cctggagatc ccactcctgc cggagaacag catgcgagcc     2040

gtcattgact gtgccggaat cctgaaactc agaaactccg acattgaact tcggaaagga     2100

gagacggaca tcgggaggaa gaacacacgg gtacggctgg tgttccgcgt tcacgtcccg     2160

caacccagcg gccgcacgct gtccctgcag gtggcctcca accccatcga atgctcccag     2220

cgctcagctc aggagctgcc tctggtggag aagcagagca cggacagcta tccggtcgtg     2280

ggcgggaaga agatggtcct gtctggccac aacttcctgc aggactccaa ggtcattttc     2340

gtggagaaag ccccagatgg ccaccatgtc tgggagatgg aagcgaaaac tgaccgggac     2400

ctgtgcaagc cgaattctct ggtggttgag atcccgccat ttcggaatca gaggataacc     2460

agccccgttc acgtcagttt ctacgtctgc aacgggaaga gaaagcgaag ccagtaccag     2520

cgtttcacct accttcccgc caacgttcca attataaaaa cagaacccac tgatgattat     2580

gagcctgctc caacctgtgg accggtgagc caggggttaa gtcctctccc aagaccatac     2640

tacagccagc agctcgcgat gccacccgac cccagctcct gcctcgtggc cggcttcccg     2700

ccctgtccgc agagaagcac cctgatgcca gcggcccctg gcgtgagccc caagctccac     2760

gacctttctc ccgctgccta caccaagggc gttgccagcc cgggccactg tcacctcgga     2820

ctcccgcagc cggccggaga ggcccccgcc gtccaggacg tgcccaggcc agtggccacg     2880

caccccggct cgcccgggca gccacccccg gccctgctgc cacagcagta aatgaaataa     2940

tacgaaatga cctctccagc acgagcaccc actcctagtt gccacattgg agcactcagt     3000

tcagcagggg tatgctgact tcagcagaca aagacttttg aataaataaa ctgaactcac     3060

acctggtacc actcagaacc tccaactgac tgaatgccag gagctgaaca ttaatatgtg     3120

caaagattgg ctctccaaca agaaggaaag cagggaggaa gggagaccac tgtgtcacct     3180

ggaggagaag tcatctcatg acaacagaag ggaggtggcc gggctgagca cgggagaccc     3240

accgtgcagg ggcctttcat gggaacggcc cacacgcagt ttgaccccac gcccagccct     3300

tctggcaccc ctggggttca atactggaag tgccttattt aaccagacca tcagggcatc     3360

atagaattga gcattgaatt tgctactgta ggagtatttt taggagcaga aactgcaaac     3420

acatttcatt gtgaggtttt accctctgta tgaatgaaga gaacgctgga aggctgcgag     3480

aggactctag tatgagtctc caacatttgg aacgtttcct gggctgtcac gtacactcct     3540

gctgccttac acagtgcatt ttagaatctt ccagtctgtc atctcagctc ttttgtaaca     3600

tgcttccctt gtctgcgcgg ttgaaaccgt aggcttgttc atagtcgcat gctcgcatct     3660

ttgtttttaa tctggcttcg aacatagcac aagtaacttg aatagcacat caataggtta     3720

ctggacaaaa gcagaaaaac ctgttacagg atagcctgca tttgcatgtg tgtacatatc     3780

taggcatcta tttatgtata aataataaca gagccgacgt gtcctcgccc aggagggctt     3840

ccctgtcagc aataaccggc atccgttttg gaacctgcgt ctggggctcc agtcgctgct     3900

cttgctggcg tccatcgccg cctcggacgg ccgtgcattt tctcgtctca cgcagttcga     3960

ggaggaccct agaaagccag gagctgtgat tgacagtagc tgtaggttac cagacggcaa     4020

cattagaaag tgattgtaaa taacatgcaa cctaagtgta atatatttgt tcagttataa     4080

gatgattgtt tcacagaagc cttaccactc tctgcttcat ctaagaaaac caataccaaa     4140

aacgccactt taatgctcag ccctgcgttg tgtgttttca gatgagttac tgttaacagg     4200

taggtttgtg taggccttgc tgggcactct gtacaattag ttgcttatta cgtatgatta     4260

ctcacagcga tctattgttc catataacca aaaagcatgg tttattcatt gaaacacggt     4320

tgacctgaac tcgtgcctta ggaattaatg cccccttatg gaacctgcct gaattgcacc     4380

tgcgggtgga ggctccggct gtgaagtcac tgaacagaac gtcgctgatg gagaaagggc     4440

tcccgcagaa ggaacggcct gtaccgtgcg ctccggcaca atcgcgtctc ttgtgtctca     4500

ctcacggaaa gaaacaacct gaaggccatc ccgtcggtct gcacgtaacc gtgaagacgt     4560

gtggccgcgt cccacctgcg gctgggtacc ctgcacccgg cactgtagga gtcacgtgca     4620

gcctttctca ggggactgtc attgaaaagg aaacgtttga tgtctgtgtc agctgtcttt     4680

gtagttagga aatagatcca ataaagccgt atttttttgc tgga                      4724


<210>  1584
<211>  797
<212>  DNA
<213>  homo sapiens

<400>  1584
ggtcaaaatg gctggcaagc aggccatttc agcatcaggc aagtggctgg atggtattcg       60

aaaatggtat tacaatactg caggattcaa taaactgggg ttaatgagag atgatacaat      120

atatgaggat gaagacataa aagaagccat aagaaggctt cctgagaacc tttataatga      180

caggatgtgt cacattaaga gtgcattgga cctgaccatg aagcatcaga tcttgcctaa      240

agagcagtgg accaaatatg aagaggaaaa tttctacctt gaactgtatg tgcaagaggt      300

tattcgggaa agaaaagaaa gagaagaatg ggcaaagaag taatcatgta gttgaagtct      360

gtggatgcag ctgttatgaa gatggttaaa cttgaaacaa acaattttaa gaattatttg      420

gtctgcagat gttttacttt aaataaatgt ctattgtaat ggctggagtt attccaaacc      480

ttatactgaa taactactga atccatttac tgttaaattt ttttccaaat tttcaagatg      540

tttttagtag tgtttaacta cttcctggag ctcagaggcc actttatcag ttttcctcac      600

tggttggata gcccatcagt ttatgtaagg atgtaacttc catgagttat agccttatgg      660

aagctactaa ataaaaaagg gggtatgcac cccctagttt gccaggattg aaaaacagcc      720

tcttcactgc tatccaaata gatttgattt tgcatcctat catttaaaaa gaaattctgt      780

atgcactcca acatagg                                                     797


<210>  1585
<211>  9580
<212>  DNA
<213>  homo sapiens

<400>  1585
cagaacactg cgtgtcctgt gcgcgagtac gggtccggcc gcgggtccca ccgcaagcgg       60

gcgtgtgcag ctgcggctgc ctggcgggcg agcttaggag ggagctggag ctgcggagcg      120

gcgggaacag gagcaggccg agggtcctct ggccagaaga aatctggcct cggaacacgc      180

cattctccgc gccgcttcca ataaccacta acatccctaa cgagcatccg agccgagggc      240

tctgctcgga aatcgtcctg gcccaactcg gcccttcgag ctctcgaaga ttaccgcatc      300

tatttttttt tctttttttt cttttcctag cgcagataaa gtgagcccgg aaagggaagg      360

agggggcggg gacaccattg ccctgaaaga ataaataagt aaataaacaa actggctcct      420

cgccgcagct ggacgcggtc ggttgagtcc aggttgggtc ggacctgaac ccctaaaagc      480

ggaaccgcct cccgccctcg ccatcccgga gctgagtcgc cggcggcggt ggctgctgcc      540

agacccggag tttcctcttt cactggatgg agctgaactt tgggcggcca gagcagcaca      600

gctgtccggg gatcgctgca cgctgagctc cctcggcaag acccagcggc ggctcgggat      660

ttttttgggg gggcggggac cagccccgcg ccggcaccat gttcctggcg accctgtact      720

tcgcgctgcc gctcttggac ttgctcctgt cggccgaagt gagcggcgga gaccgcctgg      780

attgcgtgaa agccagtgat cagtgcctga aggagcagag ctgcagcacc aagtaccgca      840

cgctaaggca gtgcgtggcg ggcaaggaga ccaacttcag cctggcatcc ggcctggagg      900

ccaaggatga gtgccgcagc gccatggagg ccctgaagca gaagtcgctc tacaactgcc      960

gctgcaagcg gggtatgaag aaggagaaga actgcctgcg catttactgg agcatgtacc     1020

agagcctgca gggaaatgat ctgctggagg attccccata tgaaccagtt aacagcagat     1080

tgtcagatat attccgggtg gtcccattca tatcagatgt ttttcagcaa gtggagcaca     1140

ttcccaaagg gaacaactgc ctggatgcag cgaaggcctg caacctcgac gacatttgca     1200

agaagtacag gtcggcgtac atcaccccgt gcaccaccag cgtgtccaac gatgtctgca     1260

accgccgcaa gtgccacaag gccctccggc agttctttga caaggtcccg gccaagcaca     1320

gctacggaat gctcttctgc tcctgccggg acatcgcctg cacagagcgg aggcgacaga     1380

ccatcgtgcc tgtgtgctcc tatgaagaga gggagaagcc caactgtttg aatttgcagg     1440

actcctgcaa gacgaattac atctgcagat ctcgccttgc ggattttttt accaactgcc     1500

agccagagtc aaggtctgtc agcagctgtc taaaggaaaa ctacgctgac tgcctcctcg     1560

cctactcggg gcttattggc acagtcatga cccccaacta catagactcc agtagcctca     1620

gtgtggcccc atggtgtgac tgcagcaaca gtgggaacga cctagaagag tgcttgaaat     1680

ttttgaattt cttcaaggac aatacatgtc ttaaaaatgc aattcaagcc tttggcaatg     1740

gctccgatgt gaccgtgtgg cagccagcct tcccagtaca gaccaccact gccactacca     1800

ccactgccct ccgggttaag aacaagcccc tggggccagc agggtctgag aatgaaattc     1860

ccactcatgt tttgccaccg tgtgcaaatt tacaggcaca gaagctgaaa tccaatgtgt     1920

cgggcaatac acacctctgt atttccaatg gtaattatga aaaagaaggt ctcggtgctt     1980

ccagccacat aaccacaaaa tcaatggctg ctcctccaag ctgtggtctg agcccactgc     2040

tggtcctggt ggtaaccgct ctgtccaccc tattatcttt aacagaaaca tcatagctgc     2100

attaaaaaaa tacaatatgg acatgtaaaa agacaaaaac caagttatct gtttcctgtt     2160

ctcttgtata gctgaaattc cagtttagga gctcagttga gaaacagttc cattcaactg     2220

gaacattttt tttttttcct tttaagaaag cttcttgtga tcctttgggg cttctgtgaa     2280

aaacctgatg cagtgctcca tccaaactca gaaggctttg ggatatgctg tattttaaag     2340

ggacagtttg taacttgggc tgtaaagcaa actggggctg tgttttcgat gatgatgatg     2400

atcatgatga tgatcatcat gatcatgatg atgatcatca tgatcatgat gatgatttta     2460

acagttttac ttctggcctt tcctagctag agaaggagtt aatatttcta aggtaactcc     2520

catatctcct ttaatgacat tgatttctaa tgatataaat ttcagcctac attgatgcca     2580

agcttttttg ccacaaagaa gattcttacc aagagtgggc tttgtggaaa cagctggtac     2640

tgatgttcac ctttatatat gtactagcat tttccacgct gatgtttatg tactgtaaac     2700

agttctgcac tcttgtacaa aagaaaaaac acctgtcaca tccaaatata gtatctgtct     2760

tttcgtcaaa atagagagtg gggaatgagt gtgccgattc aatacctcaa tccctgaacg     2820

acactctcct aatcctaagc cttacctgag tgagaagccc tttacctaac aaaagtccaa     2880

tatagctgaa atgtcgctct aatactcttt acacatatga ggttatatgt agaaaaaaat     2940

tttactacta aatgatttca actattggct ttctatattt tgaaagtaat gatattgtct     3000

cattttttta ctgatggttt aatacaaaat acacagagct tctttcccct cataagtagt     3060

gttcgctctg atatgaactt cacaaataca gctcatcaaa agcagactct gagaagcctc     3120

gtgctgtagc agaaagttct gcatcatgtg actgtggaca ggcaggagga aacagaacag     3180

acaagcattg tcttttgtca ttgctcgaag tgcaagcgtg catacctgtg gagggaactg     3240

gtggctgctt gtaaatgttc tgcagcatct cttgacacac ttgtcatgac acaatccagt     3300

accttggttt tcaggttatc tgacaaaggc agctttgatt gggacatgga ggcatgggca     3360

ggttctcctt tctttggaaa cacatccatg ctgggatgca cagttctttt cctaaggatt     3420

gtgtttactc ctgactgcaa cgtcttggcc actgtttgga gcagtttggt ctgaaggtca     3480

ttaaggatct gcttgcatct tgtttcatgt cctccgtgac agactgcaga ccatgttaga     3540

agagaaggaa ggtttgtgga tcaagagggt tgacattagg tttggtgaga tgagttgctt     3600

ggcacagatc agcagaacag gaccctggtg ataaggcatc tggctttgct aaccacttat     3660

catcttccat tattctcttt cttaactaag tagacccgaa agtgcacttt tgaagtctgg     3720

tttagatggc gagattccga atctacaatg atcgagtact ggtggccact tttctccaac     3780

attaagtaaa gaggaggaga ttccaccttc agaaagtgct gggaagcatt ggctttcttc     3840

ccacattggt agaagagatg gaggaggaaa ccagggtgca catttctaca gatccccttt     3900

gcctgctggt gtttgccttg taagataagt cactgggggg aaggggaaat ctatgaaatc     3960

caagataaag gcatagtctt tcagctctat tggtgttaaa agtatatttg tgtccaaatg     4020

ttaatcaaca caaatgtaca gtactcagta ctgacttttt tcacttcaaa atgttttcaa     4080

gggaaattca gcagacaccc aactgtattt aattagtgaa aagatctata aagactctta     4140

ctttgaataa acacattaag taagtgtgtc aaaatatttg gaatgccagt tatctatgag     4200

cgcatatctc ttacagagtg tattttgttt tcattaaggt atctctgtgt atctacactg     4260

gactaatttc atagggatct gattctatgt gatccactgt agaaagctac tgattacttc     4320

tgcagtaaca gcagctctaa ttagcatcag atgaccaaag cggaaatggg agtttcagcg     4380

ctaacaaggg cagccttcat tgaagaatgc atgggtaggc aatatataaa ttacattttg     4440

aaaagcctca tctgtcacca acaaatatct catttttctt cagtgataaa agcatattca     4500

agttaccagc tcctcaattt gaaaatcagt tgctgattaa ataaataggg ggaagcatct     4560

tgttcaggga caacacgtta gagagattct tatcaaagca agccaagcaa ggtttccgcc     4620

attcagtgtg atcttagttt gacacggtga ccctaaaaca ccatcatttg ccccagaact     4680

ggagcacaat aagttaaatc atttacctgt ctcacttctt cttggcgtgc ttaaaagcaa     4740

aaatgattcg ctacttcctg tccttcagtc cgggcatttg gggtgccact gaagacaggg     4800

gttatctgct gaggtttggg tgtcttgcag gaagtatctc attgcagttg attttgatga     4860

aaccaaacag taactagggt ccatgcagac cgtgactccc tgattacatc tagccatgcc     4920

ctacttattt cagagagaaa gagaggggga ataaaggcag tattgccaca ctgattagaa     4980

gcacattcat tccactttga tgttgaatat ttttgaccga tacatgcttg agtatctttt     5040

taatagagca catgaaggaa gaagcacaca atatagagaa ggaattgaga atgccaatta     5100

catatttatt tttccatacc tgattttttt caagtctgta ataaaaaaag tataagttga     5160

gattaacata ggttattttt catgaagtat agcaaacgat ctagaatgtg ataggagtgt     5220

ggtttccatt tctttttttt tttttttaac agacttttgt gctgtagtaa gaatgtctta     5280

gaagttgtgt cttcgagttc ctcaaacacc ggacagggct cccccagagc tgcctcagcc     5340

tttgatttgg tccatattca gacacttcct gtcttgcata cactctgagg atgggccgct     5400

tctagctgcc gcccgtctcc ctcttgcctt cttgtctcta aatcagacac tcccaagcac     5460

tccatctgct atactaggag agtgggagag ccaaagcatt ttggagtcca tgtaaagtgc     5520

ctgggaaaag agatgtaaga gcagtgggag tttatataat tagcgaattc ttttctcaga     5580

attcagcgga aatgtatttc tgttgttatt atttacaaaa ttgtggcctc agaggagctg     5640

tcttttggaa aataagtttt cattcatgca gttagttaga catgcacgat gtacttgaat     5700

caataaactg tggaccagaa aagggctgct taaatgaatt cacgtgttct aattctcttt     5760

cgaggctgtt gatgacctcc tggattcata cccccatgat ctgtcttgct cttgcctctg     5820

ttctttgata aagcacatca gactatgtga cacccatctt ttcaagaacg acctaaaagc     5880

aatgacaaca ggcaggagag aattaccact ggcctgggca cagtgacagc agaaggccca     5940

cctgagcttg gagagttggc gagataaggc aaaatcaagg tgcaacagtg ggccatgttc     6000

caagggtgaa tggatctgag agtccgctga tgttccttac tgatcagaac agggaccttc     6060

taacgaaaca gccagagttc cttgaatcag gcagaagttc tttagagaca ggaagccaga     6120

gctattgata atatccgaac gacagaggaa ggaatttctt attagaaatt ctaaaataaa     6180

acaagtgggg atttggttgg atacccttag aagctacatt tttctctcat ccctaagata     6240

gatatctcaa gtgtatatct gacacctctt ggctttgaca cggctctgct tctcaagtga     6300

ccatttgttt taagtctgtt gtctagaatt ctttgtgggg gctggacctc tgaaaaagat     6360

tctcactgca gaggctttaa atctgtgttt ttttccactc cctccgtcct gggatgtatt     6420

cggtaggaca tttcatttat atcaggatat tggctgattc agctctcttt catcgttatt     6480

attcaggcct ccctccacca ccttgttctt tattgcctaa gtattgccct ccccaattct     6540

tcatcgtaat agctctaaat ttagtttgac ccaaattaat ttttgttcca acagatatat     6600

tttaagacag agaagcctct ctcaggagcc agatgatctg aagatgatgc taatccccaa     6660

atacgaagtt cctccagcta actctcctct gagctccctc ttcttagctt tgggattggg     6720

gatggtctca tccttgccag gaatcccttt gttgctccca gtgtctctga tgagcttctc     6780

ctccctccca gagacaatgc aggggtggtt ttcagcagaa tgtgccacct gcacttctga     6840

ttgttctgag acccagccca gaggggtgga gaaggcgcac aaaccctatt ccaataaact     6900

gcctgcagag aaccacagcc tgctaatagt cgttgaggtc tcagccccct aaggtctcca     6960

agctcatttg accagcgcag ctgcgacttc ggctgtctgc ctctggcagg tgccaatatc     7020

agcatcttgt cccactgcca tggggagtta atttttgctc cagggcagct gccaagccca     7080

gcaccggcat caatagaagg ttttctctga ttttcttctc ttcctctcag gctaggcttt     7140

cttaccaatc cccaattttc ttctgtaggg cgccaggaga ctggccagag atctttagac     7200

tcttacttag tttgaacatc tcttgctgct cacacccagg cttcttcagc agaaagcatg     7260

acccatagta ggtactcaga aactggttga atgaaaagcc ttgacattta agggctttat     7320

tctgtcatac ggtagcaaga actggcctat tggcatcgta ttcctggcat tgagctgtat     7380

tgaccctgaa tgtgtcctcc tgaggttttt gagggtgacc taggagaaag ggtctgaaaa     7440

agcactggga tccaagtgac tttaaatctg cccgtggcat ttcctgctga gaggcgagaa     7500

actagcatct ctcccaacag gctcacatcc gccaggaagg acagagccca aaacgggggt     7560

agactttgtg ggaaattcgc cagttagtcc gctgagattt taatctgcct caagcacagg     7620

atgctgacaa gaaaggtaga ccactccccc gatcccagac aaaccccagg ggtgacaact     7680

tctccatcag tatcctgaga agcaacatca aatgcttacc aagtcagcac gtttactgag     7740

tgagtactct gacggaataa accagcattt ggagctgaac ttgagaacac agggccctct     7800

gacagcagct tagggaaaca cccatccctt ccagattggc agaatccttc catttcatgt     7860

ccttcggaga cgctgtattc tctttacaaa tcattcatga aactgagact cagtctccca     7920

ggggtaagtc ctgggccacg tgcaaacaat ggcaaatcca gctcttccat gatagagaag     7980

gcaaacacac ccaccttcat cctgagccta aaaggccacc tctgagcact tgggcagcca     8040

ctcctctggg cctcagaggg ccatgagctt ggccaggtag gcacagcggc ggggaagtca     8100

cagctgtcag gtaccggcca tggtgcaggt gggaatagga gatgccagag ctgctttagc     8160

tgaggaaagc aaacagtcag cagtgctcaa aggagcaaaa cttcgaatgt gcacattgac     8220

ccctgacacc tgcaagcata acacagatcc taagactaga gtgaagtagg aagaagaatt     8280

agaaaatcca gtggatgtcc tgagtatagg gaaccagggc cgttgaaaat cagtaaaggt     8340

tgattacctg gggcgagacc gggtgactgt ggcagtgcag gtgaaggtac cctggacctt     8400

ctcagttcgc tggcacataa ggctccgcca ataaagcgtg gttctctctg tcacacacac     8460

acacacacac acacacacac acacacacac acacacacac acaatgattg gagggctata     8520

tgatccagca ttagcttcct ggtgtgccaa gcatgcttga tcgggaattt ttttttatta     8580

ttattatttt ttagctgtag ctgaaggcat ttctcggatg tggagaggag aatggaaatc     8640

gcagaaccaa atcagtttgc cctgccatat ttggctgtgg tctgtcattg ggcatttctg     8700

atgtgctttt ctggattcag gaagagctga ttgtcctccg agggttgaaa aaaaaaaaac     8760

agtttcagaa acctgaatcc agggccttat agttctcctc attatctatc ttcttctccc     8820

ttccctcgcc caagggagtg ggggaaacac ttttcactgc agagtttgct ttaaagtttt     8880

cccatcttgc gtgcattatc ccttgatatt aaaattattt tctcagttta atccaactcc     8940

tgctgagaag ctgtgtgaga tttaggctgt ggggtttttt tcttgtactc ttttggatgg     9000

tgttgcattt ttcactctta acccgagggt gtgtttcagc ttatgttcgt tctgtttcat     9060

gcaggtttat agcacggtag agtagaaggc ggcttctgat ttttagggta tttttagaat     9120

tcattcctga gtgaggggtt cagacaccca gtctcctcgg aacaggggtg aggggtcgac     9180

tgagctttgt tgagaagcct ccagttaggc ttcgggcggg tctccatgtt atattgtgtg     9240

tttactgagc ttcccactgg tagaagatga cacatttgtc catcgtcctg tgtatctgct     9300

ttccagagga caccggagca ttctcctggg gtcactccca catggctgcc tcacatagct     9360

gttttgcaac agcctttatt gccaacaccc ttggaagaac atctcctgta gaagtacaag     9420

ttttgcaata tggactttgg aagtggtttt gtgatgttcg aattttctgt tagcctattg     9480

ctcaagcact acagaatgta catagtccct ttggccatcc tctcacccca gaatatccta     9540

ataaacattg ttttcttttt taaaaaaaaa aaaaaaaaaa                           9580


<210>  1586
<211>  3082
<212>  DNA
<213>  homo sapiens

<400>  1586
agaagaccac agaaatgcct ccaggaggca ggctgggatc cagggtccaa ccaatattct       60

tgtgagagtg tgaagccaag gaacacgaaa gaggggaaca ccttggctaa gaatgtattc      120

gtgacagagg agaaggggag gaacaggaag cctccagcta gtcgtttgga atctggcaac      180

catttctgtc agctttctca ttcctagatt gatgcagatt gcttaattcc ttgagcttaa      240

ccagctcgaa aaagcagtgg aagcagctca cacatttttc gtggctaacc ctgagcacat      300

ggaaatgcag cagaacattg agaattacag ggcgacagct ggtgttgaag cattgcagtt      360

ggtagacaga gaagccaagc cacacatgga gagttacaat gcaggagtta aacattatga      420

ggctgatgac tttgagatgg ctatcaggca cttcgaacaa gccttaagag aatatttcgt      480

tgaagataca gaatgccgga ccctatgtga ggggcctcag agatttgaag aatatgagta      540

tttagggtat aaggctggtc tgtatgaagc tattgcagat cactacatgc aggtgcttgt      600

ttgtcagcat gaatgtgtga gggaacttgc cacccgccct ggccgcctct ctcccatcga      660

gaattttctt cctctgcact atgattacct acagtttgcc tactatcgag ttggtgagta      720

tgtgaaagcc ctggagtgtg ccaaagccta tcttctatgc catccagatg atgaggatgt      780

cctagacaat gtggattact atgagagtct gctggatgat agcattgacc cggcatccat      840

tgaggccaga gaggatttaa caatgtttgt gaaacgtcat aagctggagt ctgagctgat      900

aaaatcagct gcagaaggtc tggggttttc atacactgaa ccgaattatt ggatcagata      960

tggaggacga caggatgaga atcgggtccc ttcaggagtg aacgtagagg gagcagaagt     1020

tcatggattc tcaatgggaa aaaagctatc acccaagata gatcgagacc taagagaagg     1080

tggtcctcta ctctatgaga acatcacatt cgtctacaac tcggagcagc tgaacgggac     1140

tcagcgggtt ctcctggata acgtcctgtc ggaagaacag tgccgggagc tccacagcgt     1200

ggccagtgga atcatgcttg ttggtgatgg atacagagga aaaacttcac cccatacacc     1260

caatgaaaag tttgaaggtg caactgtcct gaaagcactc aaatctggtt atgaaggtcg     1320

agtcccactg aagagcgctc gtctgtttta tgacatcagc gaaaaggctc gaaggattgt     1380

agaatcttat tttatgctga actcaactct gtatttttcc tatacacaca tggtctgccg     1440

aacagccctg tctggtcagc aggatagaag aaatgacctc agtcatccca tccatgctga     1500

caactgtttg ttggatccag aggccaacga atgctggaag gagcctcctg cttacacatt     1560

tcgagactat agtgctctcc tatatatgaa tgatgacttt gaaggaggag aattcatatt     1620

cacagagatg gatgctaaga ctgtgactgc ctctataaaa ccaaaatgtg ggcgcatgat     1680

cagcttctca tctggaggag agaaccctca tggggtgaag gcagtcacca agggaaagag     1740

gtgtgctgtg gctctgtggt tcaccttgga cccactttat agagaattgg agcgaataca     1800

ggctgatgaa gtgattgcaa ttctggatca agaacagcaa gggaagcatg aactgaatat     1860

caaccctaaa gatgagctat aaaaatgaga aagaatgttc tatcaaatat ttatttaaat     1920

tgttaatctt atgagaacct ttttattttt gtacagagcc atggtataaa ttaacaggtt     1980

aatgtcagtc atcagatctt ccttctcttc ctaaggatgc ttgtgttgcc tcaatctatc     2040

aatctatctt tcttgttttg ggttgttttc tctctctctc tctctctctc tcttcttaga     2100

gacatggtct aaccatgttg tctaggatat agggcagtgg ctattcacag atgtgatgat     2160

agcacactgg agcctcaaac tcttaggctc aggcgatcct tcaagcctcc cggggagctg     2220

ggaccacagg cacgtgccac cacacccagc tctctttctt ggtttttcat catttcatgt     2280

atctatcaaa gcccagttca cctcctcccc caaacacaca cacacacaca cacacacaca     2340

cacacacaca caattaagtt gctgcaaatt caaaagctta gagagaataa gcttcttggt     2400

ggtgaaacta caactctcac gtgtgctcca gttctaaaat taacctgtgc ctggtctctg     2460

aagccctttc ttgctctgtg cctttcagcc acatccttag gtgctaacgg ccatgagctc     2520

cgactctcca aagtgagctc cactttgggt ctgaggagcc cctggcagag tccacgctgc     2580

ctcaggtatc atgggcgtaa tgatcaccca ggctccggga gatctcatgg atgattactg     2640

tatgagacag aggggacttc agtctttcca gggccttggt ggaatttttg gctctggtgt     2700

tttcgccaga caataaactt acactggaag ctttgattca ccctccacag tactccagaa     2760

aggactgtcc tataagttgt acactttaaa aggtcatgta gaggttgtag tagaatggct     2820

tttcaccctg gtgactttgg aagaaactct tgaatactgc ctgcatccgg gcaccatggc     2880

caggttgcct aggagtgggg tccactgatg aaaagaggtg ttttgtactt acataagaaa     2940

aataaatttc tgattgattt taaccgtcat ctgcttatat tttgggggcc cctcctcatt     3000

gctgctatcc agcacacaga tttgtgcttg tgtctgattt gtttaataaa gggaggctta     3060

ttttaaaaaa aaaaaaaaaa aa                                              3082


<210>  1587
<211>  3715
<212>  DNA
<213>  homo sapiens

<400>  1587
atccacttgt acaaccagaa gggagctcac gtgtaaagcg cctcgtcccc ggccggcctc       60

aagcggcgct agctctctgg ctggcgctgg agtgtgccgc ccctggcagc cccgccgctg      120

cagcggggag cctgggagag cggctctcgg agtctcaggc agcaggagga gcgtgtgagc      180

tgtgggcgtc cctttaagag cggctggcca ggcacggcct ccgcctctca gtacgcggag      240

cgccggcggt cacctggggc tcgcggagcg gccagatcgc ggcggagtcg gcgcgcttcc      300

ccgagggaag gtgggagagg ggacccggac gcgaggtgcc ccgaagccct ctcgagcgta      360

accgtcccgc gcctctctga ggcggaggat gcgggagcgc atctgggcgc cgccgctgct      420

gctgctgctg ccgctgctac tgccgccgcc actgtggggc ggccccccgg acagcccacg      480

ccgggagctg gagctggagc ccgggcctct gcagcccttc gacctgctct acgccagcgg      540

cgcggccgcc tactacagcg gagactacga gcgagcggtg cgcgacttgg aagcggcgct      600

gcgcagccac cggcgcctgc gggaaatccg cacgcgctgt gcccgccact gcgcggcgcg      660

ccacccgctc ccgcccccgc cccccggcga gggccccggc gctgagctgc cccttttccg      720

ctccttgttg gggcgggcgc gctgttatcg cagctgtgag acccagcgcc tcgggggccc      780

cgcatcccgc caccgcgtca gcgaggatgt gcgcagcgac ttccagcgca gagtgcccta      840

caactacctg cagcgggcct acatcaagct taaccagctc gaaaaagcag tggaagcagc      900

tcacacattt ttcgtggcta accctgagca catggaaatg cagcagaaca ttgagaatta      960

cagggcgaca gctggtgttg aagcattgca gttggtagac agagaagcca agccacacat     1020

ggagagttac aatgcaggag ttaaacatta tgaggctgat gactttgaga tggctatcag     1080

gcacttcgaa caagccttaa gagaatattt cgttgaagat acagaatgcc ggaccctatg     1140

tgaggggcct cagagatttg aagaatatga gtatttaggg tataaggctg gtctgtatga     1200

agctattgca gatcactaca tgcaggtgct tgtttgtcag catgaatgtg tgagggaact     1260

tgccacccgc cctggccgcc tctctcccat cgagaatttt cttcctctgc actatgatta     1320

cctacagttt gcctactatc gagttggtga gtatgtgaaa gccctggagt gtgccaaagc     1380

ctatcttcta tgccatccag atgatgagga tgtcctagac aatgtggatt actatgagag     1440

tctgctggat gatagcattg acccggcatc cattgaggcc agagaggatt taacaatgtt     1500

tgtgaaacgt cataagctgg agtctgagct gataaaatca gctgcagaag gtctggggtt     1560

ttcatacact gaaccgaatt attggatcag atatggagga cgacaggatg agaatcgggt     1620

cccttcagga gtgaacgtag agggagcaga agttcatgga ttctcaatgg gaaaaaagct     1680

atcacccaag atagatcgag acctaagaga aggtggtcct ctactctatg agaacatcac     1740

attcgtctac aactcggagc agctgaacgg gactcagcgg gttctcctgg ataacgtcct     1800

gtcggaagaa cagtgccggg agctccacag cgtggccagt ggaatcatgc ttgttggtga     1860

tggatacaga ggaaaaactt caccccatac acccaatgaa aagtttgaag gtgcaactgt     1920

cctgaaagca ctcaaatctg gttatgaagg tcgagtccca ctgaagagcg ctcgtctgtt     1980

ttatgacatc agcgaaaagg ctcgaaggat tgtagaatct tattttatgc tgaactcaac     2040

tctgtatttt tcctatacac acatggtctg ccgaacagcc ctgtctggtc agcaggatag     2100

aagaaatgac ctcagtcatc ccatccatgc tgacaactgt ttgttggatc cagaggccaa     2160

cgaatgctgg aaggagcctc ctgcttacac atttcgagac tatagtgctc tcctatatat     2220

gaatgatgac tttgaaggag gagaattcat attcacagag atggatgcta agactgtgac     2280

tgcctctata aaaccaaaat gtgggcgcat gatcagcttc tcatctggag gagagaaccc     2340

tcatggggtg aaggcagtca ccaagggaaa gaggtgtgct gtggctctgt ggttcacctt     2400

ggacccactt tatagagaat tggagcgaat acaggctgat gaagtgattg caattctgga     2460

tcaagaacag caagggaagc atgaactgaa tatcaaccct aaagatgagc tataaaaatg     2520

agaaagaatg ttctatcaaa tatttattta aattgttaat cttatgagaa cctttttatt     2580

tttgtacaga gccatggtat aaattaacag gttaatgtca gtcatcagat cttccttctc     2640

ttcctaagga tgcttgtgtt gcctcaatct atcaatctat ctttcttgtt ttgggttgtt     2700

ttctctctct ctctctctct ctctcttctt agagacatgg tctaaccatg ttgtctagga     2760

tatagggcag tggctattca cagatgtgat gatagcacac tggagcctca aactcttagg     2820

ctcaggcgat ccttcaagcc tcccggggag ctgggaccac aggcacgtgc caccacaccc     2880

agctctcttt cttggttttt catcatttca tgtatctatc aaagcccagt tcacctcctc     2940

ccccaaacac acacacacac acacacacac acacacacac acacaattaa gttgctgcaa     3000

attcaaaagc ttagagagaa taagcttctt ggtggtgaaa ctacaactct cacgtgtgct     3060

ccagttctaa aattaacctg tgcctggtct ctgaagccct ttcttgctct gtgcctttca     3120

gccacatcct taggtgctaa cggccatgag ctccgactct ccaaagtgag ctccactttg     3180

ggtctgagga gcccctggca gagtccacgc tgcctcaggt atcatgggcg taatgatcac     3240

ccaggctccg ggagatctca tggatgatta ctgtatgaga cagaggggac ttcagtcttt     3300

ccagggcctt ggtggaattt ttggctctgg tgttttcgcc agacaataaa cttacactgg     3360

aagctttgat tcaccctcca cagtactcca gaaaggactg tcctataagt tgtacacttt     3420

aaaaggtcat gtagaggttg tagtagaatg gcttttcacc ctggtgactt tggaagaaac     3480

tcttgaatac tgcctgcatc cgggcaccat ggccaggttg cctaggagtg gggtccactg     3540

atgaaaagag gtgttttgta cttacataag aaaaataaat ttctgattga ttttaaccgt     3600

catctgctta tattttgggg gcccctcctc attgctgcta tccagcacac agatttgtgc     3660

ttgtgtctga tttgtttaat aaagggaggc ttattttaaa aaaaaaaaaa aaaaa          3715


<210>  1588
<211>  8332
<212>  DNA
<213>  homo sapiens

<400>  1588
gtgtgtggat gtgtgagtga gagggaacga gagtaagaga aagaaagaag tgaggggatg       60

taaactcgaa taaatttcaa agtgcctccg agggatgcaa cgggcaaaaa ctgaactgtt      120

caggcttcag attgtaactg acgatctgag gaaaaatgag gtgctcgatg aattttcgtt      180

tgtatttttt ggcgaggcgg gggaggtgtt gagatttttt ttttttcccc tcggggtggg      240

tgcgaggggg atgcatccta gcctgcccga cccggagcaa gtcgcgtctc cccgccggag      300

cccccccacc catttctttg ctgaacttgc aattccgtgc gcctcggcgt gtttccccct      360

ccccccttcc ctccgtcccc tcccctcccc ggagaagaga gttggtgtta agagtcaggg      420

atcttggctg tgtgtctgcg gatctgtagt ggcggcggcg gcggcggcgg cggggaggca      480

gcaggcgcgg gagcgggcgc aggagcaggc ggcggcggtg gcggcggcgg ttagacatga      540

acgccgcctc ggcgccggcg gtgcacggag agccccttct cgcgcgcggg cggtttgtgt      600

gattttgcta aaatgcatca ccaacagcga atggctgcct tagggacgga caaagagctg      660

agtgatttac tggatttcag tgcgatgttt tcacctcctg tgagcagtgg gaaaaatgga      720

ccaacttctt tggcaagtgg acattttact ggctcaaatg tagaagacag aagtagctca      780

gggtcctggg ggaatggagg acatccaagc ccgtccagga actatggaga tgggactccc      840

tatgaccaca tgaccagcag ggaccttggg tcacatgaca atctctctcc accttttgtc      900

aattccagaa tacaaagtaa aacagaaagg ggctcatact catcttatgg gagagaatca      960

aacttacagg gttgccacca gcagagtctc cttggaggtg acatggatat gggcaaccca     1020

ggaacccttt cgcccaccaa acctggttcc cagtactatc agtattctag caataatccc     1080

cgaaggaggc ctcttcacag tagtgccatg gaggtacaga caaagaaagt tcgaaaagtt     1140

cctccaggtt tgccatcttc agtctatgct ccatcagcaa gcactgccga ctacaatagg     1200

gactcgccag gctatccttc ctccaaacca gcaaccagca ctttccctag ctccttcttc     1260

atgcaagatg gccatcacag cagtgaccct tggagctcct ccagtgggat gaatcagcct     1320

ggctatgcag gaatgttggg caactcttct catattccac agtccagcag ctactgtagc     1380

ctgcatccac atgaacgttt gagctatcca tcacactcct cagcagacat caattccagt     1440

cttcctccga tgtccacttt ccatcgtagt ggtacaaacc attacagcac ctcttcctgt     1500

acgcctcctg ccaacgggac agacagtata atggcaaata gaggaagcgg ggcagccggc     1560

agctcccaga ctggagatgc tctggggaaa gcacttgctt cgatctattc tccagatcac     1620

actaacaaca gcttttcatc aaacccttca actcctgttg gctctcctcc atctctctca     1680

gcaggcacag ctgtttggtc tagaaatgga ggacaggcct catcgtctcc taattatgaa     1740

ggacccttac actctttgca aagccgaatt gaagatcgtt tagaaagact ggatgatgct     1800

attcatgttc tccggaacca tgcagtgggc ccatccacag ctatgcctgg tggtcatggg     1860

gacatgcatg gaatcattgg accttctcat aatggagcca tgggtggtct gggctcaggg     1920

tatggaaccg gccttctttc agccaacaga cattcactca tggtggggac ccatcgtgaa     1980

gatggcgtgg ccctgagagg cagccattct cttctgccaa accaggttcc ggttccacag     2040

cttcctgtcc agtctgcgac ttcccctgac ctgaacccac cccaggaccc ttacagaggc     2100

atgccaccag gactacaggg gcagagtgtc tcctctggca gctctgagat caaatccgat     2160

gacgagggtg atgagaacct gcaagacacg aaatcttcgg aggacaagaa attagatgac     2220

gacaagaagg atatcaaatc aattactagg tcaagatcta gcaataatga cgatgaggac     2280

ctgacaccag agcagaaggc agagcgtgag aaggagcgga ggatggccaa caatgcccga     2340

gagcgtctgc gggtccgtga catcaacgag gctttcaaag agctcggccg catggtgcag     2400

ctccacctca agagtgacaa gccccagacc aagctcctga tcctccacca ggcggtggcc     2460

gtcatcctca gtctggagca gcaagtccga gaaaggaatc tgaatccgaa agctgcgtgt     2520

ctgaaaagaa gggaggaaga gaaggtgtcc tcagagcctc cccctctctc cttggccggc     2580

ccacaccctg gaatgggaga cgcatcgaat cacatgggac agatgtaaaa gggtccaagt     2640

tgccacattg cttcattaaa acaagagacc acttccttaa cagctgtatt atcttaaacc     2700

cacataaaca cttctcctta acccccattt ttgtaatata agacaagtct gagtagttat     2760

gaatcgcaga cgcaagaggt ttcagcattc ccaattatca aaaaacagaa aaacaaaaaa     2820

aagaaagaaa aaagtgcaac ttgagggacg actttcttta acatatcatt cagaatgtgc     2880

aaagcagtat gtacaggctg agacacagcc cagagactga acggcaatct ttccacactg     2940

tggaacaatg catttgtgcc taaacttctt ttggaaaaaa aaaatataat taatttgtaa     3000

gtctgaaaaa aaaatattta atttaaaaaa aattgtaaac ttgcaataat gaaaaagtgt     3060

acttctgaag aaaactacat gaacgttttt gttggtattc aagtcagcta gtgtttataa     3120

ttactggata ttgaattagg ggaagctcgg ctgccctagt aacaaaacca gcaaacgtcc     3180

tgatgacaac gaagtgatga cattagccat tccttagggt aggaggaaca gatggatctt     3240

atagacctat gacaaatata tatataaata tatatataaa tatatattaa aaatttagtg     3300

actatggtaa gcttttgttc atttgtttca gacttttttc tcctgtaaaa aaatagtact     3360

gattaacttt tttaaaagaa agattttact gtaaatatgg attttttttt ttttggtctt     3420

atttctgtcc ctttccctgg tttgttatcg taacctgtag tgccaactct gcttccagag     3480

gggtagtgca ggatgaaatg ctgaccctga tgttgcttct cattcataaa taagtagaaa     3540

gttgtttctc cagtcttttg ggaacacagg acttaaaagt cacatcatgt gtagatatta     3600

caagcagcat taccaagaca tggcaaaaag agtttgtctg aattgtaatg ttgcgtttgt     3660

gaacctattc tgggattttc agaggtacaa ggttagaatg ctacaatgtt accactgtgc     3720

cttccaatgt ttatatcatc ggaaacataa cataatcaaa gtggctgtga tttaacaaaa     3780

tgattaaagt gttacctacc tgtgtagccg aagtagtgtg cagtgaggcg tttctgaata     3840

catggtcaga tttttggaaa aaaacaaaaa caaaaaaaac aagtaaagtt caaaaaccgt     3900

caaatgagaa aattgcaagt agtgtgacag agctgattga ttttgttgct ttcttgattt     3960

tttttttcaa aatgggttta ctaaaatgta gatgacttaa ctgcctcctc cttcgtctga     4020

aaaatgccaa tattcaatca tcatgcagca ttataacaag ccttataagt cctaaagcat     4080

taagttgcac ttttttgagg aggggtagtg cagtatttct ctggccagta tgaatgaagt     4140

ttatacttac catatttgat agaaacatag atcaagctat ggcacagcga ctcatcagat     4200

agctagcttt gacgtctggg cacaattgaa ccaacttcca tcgtgaatct ttataatgat     4260

tgactttggt gtatagtgca gtaaacaaat agtgctccta gttaagtatt tgtcagcatc     4320

cttttgtctc taacttgttt ctatttttac agccacacaa ttcttggcat gtattaagaa     4380

aaaaaaaaat ccctgttcaa gtagtttttc cacctatcag cactgagtaa atgccataaa     4440

tccattgaaa tggtctaaat gttccatctg ttctcctgtt ttgccagtta tatagtaatg     4500

aaatacattt gtaaatttta tgcaacaaat ggcaaacgta tcattatttt gaaattgtgt     4560

atgtaaaagt tatattttta catgtagact cttgttatta tgtgttttaa tacattgtat     4620

cagtttttgt ttttttttaa aaactgtggt ttaaaaagaa gtctcattta aatgaaatag     4680

ctacaagaat cagaatttta tgttcatttc tgaaaatgta agaacaaata agatagttac     4740

cacgtggtca tcttttacaa acccataaac attttgatta gctgtgtgtg tgttgaaaaa     4800

ctgtaaatat gttcagtagc gataaaacta aaataacttt gatttgttga taagttccta     4860

aaatgtggag gtggattaaa accttaggag aatagcagaa atcaaacttc atgaaaagtt     4920

attttggggc tttcctgtga aatgtatgaa caaagaggct cagagaagga catggaagac     4980

aataatgtat actctctcct cctccctgaa taatgaaaac catgtgtatt tgttccctcc     5040

gtatgttaaa gatttccttt tagtggtaca ttctgcactc attttgtata gtctaccaag     5100

gcgggtatcc ctaggaacaa tattatatag gaagcaggta tactctgatc acattcagga     5160

taagtgtaca gaagaaaata cggtgtttac tctttaggga actggaaaca ctccctgcat     5220

tgatgtacat tttaagaatg gcacttttga tacatgttat cataaaggtg cttaatagag     5280

ctgaattaaa gtttttcaaa tctgtaaaca aagcaaaaaa gtaaattgta gtcatttgat     5340

tattttttaa attggtgctt tatattttgt tctcactcag agtaaaagct gcaatttatt     5400

gttcaccagc tttgatgtat tcattactca gtaatgcaat acctctattg ttgaattccc     5460

tttggaaata agtgaaaatt ctaacggcca ctgaaagctg ctcgctaggt tttgcttggt     5520

ggagaaacat aatctgcacc tatccatatt aattgggttg tatccccatt aaaaaagaaa     5580

aaaagggaat gtggcctttt tagtgtgttt tttattgttg ttgttttgta attatcaaac     5640

ccaggtaaga tattggtatc ctgcactgga ttttcaaatg aagttcagca gaagacagtt     5700

aagattaaag tactatacaa aaatttcaaa agggtccata ctacgctatc tgtatgacga     5760

cacttaggct ggggatctct ttcagaaact cggactttaa aagcaacttg gagcagttga     5820

tccacctcca cattcaagta atttatgaat atgcagaata gggatctgtt catctagaaa     5880

tttttaccat ttgtcttctg tgtagctgca aggaacacta atgtttatac aactgtcagt     5940

ccacccagtg gtgcaactgg ttctgattca gtcttccgat tcctttttat ttttcacttt     6000

ttcctatttc tgaatttttt tttttatttg tgatcttgat tttgatgagg ggttggggag     6060

tggggaggga gtcgaaccaa gacttggagt taagaggatt ttcatctttt gcatccaaca     6120

ggcagaatat gatctgtgtc caaaagtgaa cttgagtcag gaatgaatca atttcagcat     6180

aaacaagcac aaaaatttag tctgctggct gactggaagc aaaaaagtca agatggaata     6240

tgatgaattc caacacaatg gggcaccaag gcctttaggc ctctcttttt attttgcttt     6300

ggttttgttt gtttttcttt agagacatgc tctttctcat gggacttgaa gtggactcat     6360

ctttgtgcag tgctggtttt gccatactca tttcaagtat tatagacata tgtaatggtg     6420

aaaatatatg aactgtggcc tttttcattc ttgttacttg tgatgcaatt aagtgaagat     6480

aagaaaaaaa aaaaaaaagc agagatttac catgtatcag tgcctggctt tttgttataa     6540

agctttgttt gtctagtgct cttttgctat aaaatagact gtagtacacc ctagtaggaa     6600

aaaaaaaaaa ctaaatttaa aaataaaaaa tatatttggc ttatttttcg caggagcaat     6660

ccttttatac catgaatatt acaaaaaaat tgtcagattc tgaatatttc ttctttgtag     6720

atttttggaa tcattatgag taaaagtttg ttactttatt ttactattta aaagatgtta     6780

ttttaccatg tgttaccaag atgaaactgt atgggtagct tttttgtttg ttttttgttt     6840

tgtttttgtt tttgtttttg tttttagttg taggtcgcag cggggaaatt ttttgcgact     6900

gtacacatag ctgcagcatt aaaaacttaa aaaaattgtt aaaaaaaaaa aaagggaaaa     6960

catttcaaaa aaaaaaaaaa agataaacag ttacaccttg ttttcaatgt gtggctgagt     7020

gcctcgattt tttcatgttt ttggtgtatt tctgatttgt agaagtgtcc aaacaggttg     7080

tgtgctggag ttccttcaag acaaaaacaa acccagcttg gtcaaggcca ttacctgttt     7140

cccatctgta gttattcgat gaagtcatgt acatgaccgt tctgtagcaa taaatgtgcc     7200

atttttataa actgtttctg acacttgttt catttcattt tgcattgtcc atatagctat     7260

gattctcttc tgtaagtaaa acgcatctat atttcatttt ccaagtgttg gaggtattga     7320

cagcttaaca aacaaaacat acaaaaaaaa tcacaaaaac aaattgaaaa gcaaagcaca     7380

tgattgatca aggaagagat gcccttaatg aaaatggaac gggatgcatg caaaacaaaa     7440

agaaaactgt ctagaggatt aactaattga aggaatataa ttaatgtgtg tgtaacactg     7500

aagctatgca tttgaagagc tctgaactgc accagtgttt tcggttgtgc tgcaggttgc     7560

taagtcaagt cagccttaac cttttgcacc agttggtcgg ctgtttggca gaacattctc     7620

agatcttttc agtcaaaaat ctaagatgat ttattttgta tcactttgtt aaaagctgaa     7680

tattgttaac tacagttaat attaacactg tatttatact ttctcaaact acatccgccc     7740

caccacttct ggttgcctct gttgactatt aatccagatg taaacaacca gatgtttttt     7800

tctaacttgt acaaactgac gtgtgtcaac tatcatggaa ggaaaaaaat gtacagatta     7860

aaattattca gtgttatgta ctgtaagtta atatttttgt agaatggaca tcaatctact     7920

ttgcaaaatt tggaggctat ttcaacattg cactgtagaa atgtaaagta atgtatgcaa     7980

tgtaaaggaa agcccgcggt agctgagcgc ttcataacag aatgttctaa tcaagtacgt     8040

ggtatttggg gatgtctcca atattgctct tgtattcttt ctaattgggt ttagtgacta     8100

gttgaaggaa aatgttataa cgccatttgg ttcacatgtg aagtgccctc catagccaaa     8160

tgttgggatt tttttttttt tcgtttttgg ttggactgtt tgcagatatt taaattttat     8220

gaaatttcca aagattttgg ttgataaccc ccttttacct tctaaatgat ttgagatgtt     8280

cttatgttct tactgtgtgt tttaaatata tataaaagag ccacaagcat tt             8332


<210>  1589
<211>  1324
<212>  DNA
<213>  homo sapiens

<400>  1589
ttcacttccg ggccgcggtc tagggcggct acgtgtgttg ccatagcgac cattttgcat       60

taactggttg gtagcttcta tcctgggggc tgagcgactg cgggccagct cttcccctac      120

tccctctcgg ctccttgtgg cccaaaggcc taaccggggt ccggcggtct ggcctaggga      180

tcttccccgt tgcccctttg gggcgggatg gctgcggaag aagaagacga ggtggagtgg      240

gtagtggaga gcatcgcggg gttcctgcga ggcccagact ggtccatccc catcttggac      300

tttgtggaac agaaatgtga agtttttgat gatgaagaag aaagcaaatt gacctataca      360

gagattcatc aggaatacaa agaactagtt gaaaagctgt tagaaggtta cctcaaagaa      420

attggaatta atgaagatca atttcaagaa gcatgcactt ctcctcttgc aaagacccat      480

acatcacagg ccattttgca acctgtgttg gcagcagaag attttactat ctttaaagca      540

atgatggtcc agaaaaacat tgaaatgcag ctgcaagcca ttcgaataat tcaagagaga      600

aatggtgtat tacctgactg cttaaccgat ggctctgatg tggtcagtga ccttgaacac      660

gaagagatga aaatcctgag ggaagttctt agaaaatcaa aagaggaata tgaccaggaa      720

gaagaaagga agaggaaaaa acagttatca gaggctaaaa cagaagagcc cacagtgcat      780

tccagtgaag ctgcaataat gaataattcc caaggggatg gtgaacattt tgcacaccca      840

ccctcagaag ttaaaatgca ttttgctaat cagtcaatag aacctttggg aagaaaagtg      900

gaaaggtctg aaacttcctc cctcccacaa aaagacctga agattcctgg cttagagcat      960

gcgagcattg aaggaccaat agcaaactta tcagtacttg gaacagaaga acttcggcaa     1020

cgagaacact atctcaagca gaagagagat aagttgatgt ccatgagaaa ggatatgagg     1080

actaaacaga tacaaaatat ggagcagaaa ggaaaaccca ctggggaggt agaggaaatg     1140

acagagaaac cagaaatgac agcagaggag aagcaaacat tactaaagag gagattgctt     1200

gcagagaaac tcaaagaaga agttattaat aagtaataat taagaacaat ttaacaaaat     1260

ggaagttcaa attgtcttaa aaataaatta tttagtcctt acactgagaa aaaaaaaaaa     1320

aaaa                                                                  1324


<210>  1590
<211>  3812
<212>  DNA
<213>  homo sapiens

<400>  1590
gggcctactc tgccgccgcc gccgcccgcc cgctccagcc gccgccgccg ccgccaccgc       60

cctccaggct ccgggacccg gcccgcgcca ccgcccccgt gcgcgccccg ccgccgccgc      120

cttcgccttc gccttttgtt tcctccgctc cggcgccccc gccccggctc gcgctttgca      180

ggggacgcag cgcgcgcccc cagcgggccc gggaaaagcc gcggcgcgcg cgcgcgcctg      240

cgcggcggac ccctccttct cctccccgcg tgcgcgtgcc cttcttggct gcgcgccggc      300

gccgcctggc gggcgggagg ggaggtggca ggcgcgtttg caggaggggc gcacctcttc      360

gctcgcgcac ccccccggaa ggtagaccgg gaaggggagg cgggcgggcg gagaggagag      420

agtggcgcgc agtccagcga gggcgggggt tggctatgtg gggggtggtg caccccgcag      480

tctagacagt ctgatccggg ctgggggcgt gtacactcgg cgcacctgcg agactacaga      540

gcctcgggcc ggcacgtgtg gggagtgtgg acacgtctgc tgcgccccgc ttctcgctgc      600

tgaggggaag ggagggggcg ggcaggtgca gcggccgggc tagtgggagg gggcggcggc      660

catggagcgg gtgaacgacg cttcgtgcgg cccgtctggc tgctacacat accaggtgag      720

cagacacagc acggagatgc tgcacaacct gaaccagcag cgcaaaaacg gcgggcgctt      780

ctgcgacgtg ctcttgcggg taggcgacga gagcttccca gcgcaccgcg ccgtgctggc      840

cgcctgcagc gagtactttg agtcggtgtt cagcgcccag ttgggcgacg gcggagctgc      900

ggacgggggt ccggctgatg tagggggcgc gacggcagca ccaggcggcg gggccggggg      960

cagccgggag ctggagatgc acactatcag ctccaaggta tttggggaca ttctggactt     1020

cgcctacact tcccgcatcg tggtgcgctt ggagagcttt cccgaactca tgacggccgc     1080

caagttcctg ctgatgaggt cggttatcga gatctgccag gaagtcatca aacagtccaa     1140

cgtacagatc ctggtacccc ctgcccgcgc cgatataatg ctctttcgcc cccctgggac     1200

ctcggacttg ggcttccctt tggacatgac caacggggca gccttggcag ccaacagcaa     1260

tggcatcgcc ggcagcatgc agccagagga ggaggcagct cgggcggctg gtgcagccat     1320

tgcaggccaa gcctctttgc ctgtgttacc tggggtggac cgcttgccca tggtggctgg     1380

acccctatcc ccccaactgc tgacttcccc attccccagt gtggcatcca gtgcccctcc     1440

cctgactggc aagcgaggcc ggggccgccc aaggaaggcc aacctgctgg actcaatgtt     1500

tgggtcccca gggggcctga gggaggcagg catccttcca tgcggtctat gtggtaaggt     1560

gttcactgat gccaaccggc tccggcagca cgaggcccag cacggtgtca ccagcctcca     1620

gctgggctac atcgaccttc ctcctccgag gctgggtgag aatgggctac ccatctctga     1680

agaccccgac ggcccccgaa agaggagccg gaccaggaag caggtggctt gtgagatctg     1740

cggcaagatc ttccgtgatg tgtatcatct taaccggcac aagctgtccc actctgggga     1800

gaagccctac tcctgccctg tgtgtgggtt gcggttcaag agaaaagacc gcatgtccta     1860

ccatgtgcgg tcccatgatg ggtccgtggg caagccttac atctgccaga gctgtgggaa     1920

aggcttctcc aggcctgatc acttgaacgg acatatcaag caggtgcaca cttctgagcg     1980

gcctcacaag tgtcagacct gcaatgcttc ttttgccacc cgagaccgtc tgcgctccca     2040

cctggcctgt catgaagaca aggtgccctg ccaggtgtgt gggaagtact tgcgggcagc     2100

atacatggca gaccacctga agaagcacag cgaggggccc agcaacttct gcagtatctg     2160

taaccgaggt ttctcctctg cctcctactt aaaggtccat gttaaaaccc accacggtgt     2220

tccccttccc caggtctcca ggcaccagga gcccatcctg aatgggggag cagcgttcca     2280

ctgcgccagg acctatggca acaaagaagg ccagaaatgc tcacatcagg atccgattga     2340

gagctctgac tcctatggtg acctctcaga tgccagcgac ctgaagacgc cagagaagca     2400

gagtgccaat ggctctttct cctgcgacat ggcagtcccc aaaaacaaaa tggagtctga     2460

tggggagaag aagtacccat gccctgaatg tgggagcttc ttccgctcta agtcctactt     2520

gaacaaacac atccagaagg tgcatgtccg ggctctcggg ggccccctgg gggacctggg     2580

ccctgccctt ggctcacctt tctctcctca gcagaacatg tctctcctcg agtcctttgg     2640

gtttcagatt gttcagtcgg catttgcgtc atctttagta gatcctgagg ttgaccagca     2700

gcccatgggg cctgaaggga aatgaggcag ctgctgtgtc cccacggaaa caaccatctg     2760

gggactgctg ggaaatgctg tgaatgcgga gggaagtgat gtttgggttc tgtagctgag     2820

agatttttat tcatttttaa ctgcccccca accccactcc aactccttct ccaccaccca     2880

ttctcccaat ggtctttaga aatagatttt catctgatat tctgcagaaa tatcaatgag     2940

acttggtatg ggacaggggc agaaaacact acataggcct ccaaggcaaa accagtccca     3000

gtttctttaa tgggaagaag ctggaattcc tggtgctcaa ttcttagtga ccccaatcct     3060

atacccaaat ctatgatatt ctgggacctc agtgattttg gtcccctccc acttctctag     3120

ttcgtcatcc tcccttccca tatccttcaa aagaaccaca ctagggtctc cacctactta     3180

tacaatgcgg atgcccaact gtttttaagg aagccagaag catcccatgg accatggggt     3240

gagtgtcctc caagagcccc ctgagctcag ccctctgcct ggagggctcc agacctttct     3300

gagccctgct tggaggcgag cattttcact gctaggacaa gctcagctgt tgaggacacc     3360

cccaccccaa atttcagttc ttacgtgatt ttaaccattc aacatgctgt tgggttttaa     3420

ttctctaatt attattatta ttgttattat tttttaggac cagttgtagt gaattgctac     3480

tgaaagctat cccaggtgat acagagctct ttgtaaaccg cagtcacaca ttagggttag     3540

tattaaactt tgtttagatg taccataatt aacttggcta gttgattgtt tgaagtctat     3600

ggaagaaata gttttatgca aaattttaaa aaatgccagt ctggtcaggg aagtaggggg     3660

tttcaatgct gttgggaacc aggaaggtgg gacagccggc aggtagggac attgtgtacc     3720

tcagttgtgt cacatgtgag caagcccagg ttgaccttgt gatgtgaatt gatctgatca     3780

gactgtatta aaaatgttag tacattactc ta                                   3812


<210>  1591
<211>  6131
<212>  DNA
<213>  homo sapiens

<400>  1591
ctccgactct cggcacctgg cctccagctt tcggaactat ggaggccgcg cccgggaccc       60

ccccgccgcc gccatcagag tcgccgccgc cgccatcgcc gccgccgcca tcaacgcctt      120

cgcctcctcc gtgttccccc gacgcccgcc cggccacccc gcacctcctc caccaccgcc      180

tcccgctccc tgacgacagg gaagatggag agttggaaga aggtgaattg gaagatgatg      240

gggcagagga gacccaggat acctccggag ggcctgagag aagccggaaa gaaaaggggg      300

agaagcatca cagtgattcg gatgaggaga agtcccacag gagactgaag cggaaacgga      360

agaaagagcg ggagaaagag aaaaggaggt cgaagaagag gaggaaatcc aagcacaaac      420

gccatgcttc ttctagcgat gacttctctg acttctcaga tgactcggat ttcagcccca      480

gtgagaaagg tcaccgcaag tacagagagt acagcccccc atatgcgccg tcccaccagc      540

agtacccccc atcgcatgcc acgcccctgc ccaagaaggc atactccaag atggacagca      600

agagttatgg catgtacgag gactacgaga atgagcagta tggggaatat gagggcgacg      660

aggaggagga catgggcaag gaggactatg acgacttcac caaagagctg aaccagtacc      720

ggcgtgccaa ggagggcagc agccgcggcc gaggcagccg aggccggggc cggggctaca      780

ggggccgagg aagccgtgga ggatcgcgag gccgcggcat gggcaggggc agccgaggca      840

ggggcagagg ctctatggga ggagaccacc cggaggatga agaggatttc tacgaggaag      900

agatggacta tggagagagt gaggagccaa tgggagacga cgactatgac gagtactcca      960

aggagctgaa ccagtaccgc cgctccaagg acagccgagg ccgagggcta agtcgaggcc     1020

gtggcagggg ctcccgaggt cgagggaaag gaatgggtcg gggccgaggc cgaggtggca     1080

gccgaggagg gatgaacaag ggcggaatga acgatgacga agacttctat gacgaggaca     1140

tgggcgacgg tggtggtgga agctaccgga gtcgtgacca tgacaagccc caccagcagt     1200

cggacaagaa aggcaaagtc atttgcaagt acttcgtgga agggcgctgc acctggggag     1260

accactgtaa ttttagccat gacatcgaac tcccaaagaa gcgagaactg tgcaagtttt     1320

acatcactgg attttgcgcc agagctgaga actgccctta tatgcacggt gatttcccgt     1380

gtaagctgta ccacaccact gggaactgca tcaatggtga cgactgcatg ttttcccacg     1440

accctctgac cgaagagacg agggagctct tggataagat gttggccgat gatgcagaag     1500

caggtgccga ggatgagaag gaggtggagg aactgaagaa gcagggcatc aaccccctgc     1560

ccaaaccgcc ccctggtgtg ggcctcctgc ccacccctcc tcggccccct ggcccgcagg     1620

ctccaacctc tcccaacggc aggcccatgc agggtggccc cccgcccccg ccccctcccc     1680

ctcccccacc gcccgggccc cctcagatgc ccatgccggt gcatgagcca ctgtccccgc     1740

agcagctgca gcagcaggac atgtacaaca agaagatccc ctccttgttt gagatcgtgg     1800

tgcggcccac gggacagctg gctgagaagc tgggtgtgag gttccctgga cccggtggac     1860

ccccagggcc aatgggccct gggcccaaca tgggaccccc agggccaatg ggcggtccaa     1920

tgcatcctga catgcacccc gacatgcacc cggacatgca ccctgacatg cacgcagaca     1980

tgcacgcaga catgccgatg ggccctggca tgaatcctgg cccacccatg ggccctggcg     2040

gccctccaat gatgccctac ggccctggag actccccaca ttctggaatg atgcccccta     2100

tcccgccagc ccagaacttc tatgaaaact tctaccagca gcaggagggc atggagatgg     2160

agcccggact cctgggggat gcagaggact acgggcacta cgaagagctg ccaggggagc     2220

ctggggagca cctcttccct gagcaccctc tggagcccga cagcttctct gagggagggc     2280

ccccaggccg gccgaagcca ggcgccggtg tccctgactt cctgccctca gcccagaggg     2340

ccctgtacct gaggatccag cagaagcagc aggaggagga ggagagagcg aggaggctgg     2400

ctgagagcag caagcaggac cgggagaatg aggaaggtga caccggaaac tggtactcaa     2460

gtgatgagga tgagggtgga agcagtgtca cctccatcct gaagaccttg aggcagcaga     2520

cgtccagccg acccccggct tcagttgggg agctgagcag cagtgggctg ggggaccccc     2580

gcctccagaa gggacacccc acaggaagcc ggctggctga ccctcgcctc agccgggacc     2640

ccagactcac ccgccatgtg gaggcttctg gcgggtctgg cccaggtgat tcgggaccct     2700

ccgatcctcg gctggctcgc gccctgccca cctccaagcc cgaaggcagc cttcattcca     2760

gccctgtggg ccccagcagt tccaaggggt ctgggccgcc cccaacggag gaggaggaag     2820

gggagcgggc cctgcgggag aaggccgtga acattcccct ggacccactc cccgggcacc     2880

ctctgcggga cccacggtca cagctgcagc agttcagcca catcaagaag gacgtgaccc     2940

tgagcaagcc cagcttcgcc cgcaccgtgc tctggaatcc cgaggacctg atccccctac     3000

ccatccccaa gcaggacgca gtgccccccg tgcccgcggc cctgcaatcc atgcccaccc     3060

tggacccccg gctgcaccgc gctgccacgg cagggccccc caacgcccgg cagcgcccgg     3120

gcgcctccac ggattccagc acacagggcg ccaacctccc cgactttgaa cttctgtctc     3180

gcatcctcaa gacagtcaat gccaccggct cctcggccgc ccccggttcc agcgacaaac     3240

ccagtgaccc ccgggtgcgg aaggccccca ccgaccctcg gctgcagaaa cccacagact     3300

ctacggcctc ctcccgggct gccaagcccg gccctgctga ggcgccctct cccaccgcca     3360

gcccgagtgg ggatgcctcc ccaccagcca ccgctcccta cgacccccgc gtgctggcgg     3420

ccggtggact gggccagggc ggagggggcg ggcagagcag tgtgctgagc ggtatcagcc     3480

tctacgaccc gaggactccc aacgcggggg gcaaagccac agagccggct gctgacacgg     3540

gtgcccagcc caagggtgct gagggcaatg gcaagagctc ggcctccaag gctaaggagc     3600

ccccgttcgt ccgcaagtct gccctggaac agccagagac agggaaggcc ggtgctgatg     3660

ggggcacccc cacggacaga tacaacagct acaaccggcc ccggcccaag gctgctgcag     3720

cccccgctgc caccaccgcc accccacccc ccgagggtgc cccaccccag cccggggtgc     3780

acaacctgcc cgtgcccacc ctcttcggga cggtgaagca gacacccaag acgggctcag     3840

gaagcccatt tgctgggaac agtccggccc gcgagggtga gcaggatgcg gcatccctga     3900

aggatgtttt taaaggcttc gaccccacgg cctccccctt ttgccagtag tgtccagcca     3960

gagctgcggc tccagccacc cttcctaggg tggcattcag ggcagcaccc agggtaggga     4020

acttgggggc aaggggaggc aggctgggtg ttcctttttt cttttctttt tcttttgctt     4080

tccgtctctt ttattttttt ttaaagtagt actttctttg agatttgtaa attgtatata     4140

accatcttaa gttctggtca gtgtggcggg ctcaggggct cctgctgagc aaaccgactc     4200

atgcccgcaa acctgtgaac tttcgccagt gcctggcctc agactctgtg ggctctgcgt     4260

ggccgggcct tgctggaggc ccagtgggtt ttctgggcaa agcatggccc cttttcccca     4320

ggacaaaggg aacagttggt gtctgggaag gtattgaacg ctcctcaccc tgtgcccgaa     4380

gagacccgga accaagacca tggcagggcc tgcgtggaag caggtccagg cgtttctaga     4440

accctagggt gcaccatcac tgtcttttca gtgcaggctg taacaaccca ctcaggagac     4500

agtgagagtg aaaaggtatt aaggaaaaag cccccagcgg cactatgggg gctccctggc     4560

gcatgcctgc tcctgtccct ggattaccac acgtgccctc cctgccaccc tccgtctaga     4620

gcaagcggat gccccccagc ctgcagcaga agcctccaca gtgagaactg gacccaaagg     4680

tagtgggggc cggtgtgggg cagagtcctg aagagccacc tctaggaggc agcccctagg     4740

agcacgcacg ttctgtcagt attaccccac ctgtcctatc aggtgggcca caccctgctt     4800

gcccacacca gggtctgtcc tggtcctcaa gccacgcacc cgctatgcct gcactgcagc     4860

ccagccccgg acagctccag gatccgtgca gtggctgcgc cgccaggccc caacaatggg     4920

gaccctgggg tggctcctgg ccaagtgttc tctgttttcc tcgcacctcc ttacactgtg     4980

tgacctgcag ggcatgaggt attgatgtgt tcgggtttcc tttcccaagc cagcagatgc     5040

aggtgttcca aggtgtgttg ctctgtggga tttgtggaca cttaagaaac ggactgagtg     5100

ggaaccctgc agccagggga tggggagcct ctgctccccc catgctccca ccctggctga     5160

gggccagcct catctgcaga gccctggagg aggcccacct atggacacag cccgagagat     5220

gggcgcaagg ggtgctgggg gaggcctgct atcctgcctc tgggccactt gaggggcctc     5280

aggaagtgtg tgcttgtggc tgcatctgcc cgtctccctg gcccaccatg tggctgcagg     5340

ccaagctctt cattgctgac catgaagaga cctagttacc tgccaaggga ttccccttcc     5400

ctcctcctca gggtggggtg aacaaggctc ctatcccacc ccaccccaaa aagagaaaaa     5460

tgaaaaactc atagtttgga gccaggaggc agggtgtcct acagggctgc acagccctga     5520

ggggtcagtg ctgggatctg gttggttggt ttgtcttttt gtcttttttt tttttttttt     5580

ttttacacaa tcattaatga gatttgtctt cagccaccag tgttggcctt gaagcagagg     5640

gcacagccct tggtgtttgt aaaataagta tgaatacaca gtgtggcagt gttgtggttt     5700

ttgttgttgt ttttcctctc cttttgagaa ttttcttttg taaaagaaaa atatttttta     5760

aaccgaaatc tgtggatgaa atagaagctg gagccctcct cttggaatat tcagcctaag     5820

aacctcatag gactatgaat tcacccgaaa ttctcatttg ccatcaggcc gagcttttaa     5880

agaaaaattg ttctctaacc aggattgtaa caaaagtgta aatactgttt cagagttgag     5940

agttggtggt gcaaatatgt atataatgaa ctgtattttt acaatgatcg ccgcatgact     6000

atttcacacc ctttttatac tccatatctg tcttccagaa acgtcacctg cctttctcct     6060

gtggtctctt aatccagtaa ttgtattact gccattaaag gatgcagtta ttttaaaaaa     6120

aaaaaaaaaa a                                                          6131


<210>  1592
<211>  8422
<212>  DNA
<213>  homo sapiens

<400>  1592
gcgcgcagtg agaggcgccg gggctgccgc ccggtgctcg gcgcgctctc gggagccgcc       60

cgcccgctgg tcccgcagcc ttccgggagg aagcggtgcc ggcagcgtcc agggcgcgct      120

ctcgggcacc ctcacctgcc ggcgcccggc cgcttacccg gcagggcgtg cgcagggtag      180

ggtgcgggac cggggggacc tggaggcaga ggggagaacc ggccgtccgc gccgcagcac      240

agccgctggg agcgcctcag accccgcgcg gggcgccggc tccatggcga ccgggctcgg      300

ggagccggtc tatggacttt ccgaagacga gggagagtcc cgtattctca gagtaaaagt      360

tgtttctgga attgatctcg ccaaaaagga catctttgga gccagtgatc cgtatgtgaa      420

actttcattg tacgtagcgg atgagaatag agaacttgct ttggtccaga caaaaacaat      480

taaaaagaca ctgaacccaa aatggaatga agaattttat ttcagggtaa acccatctaa      540

tcacagactc ctatttgaag tatttgacga aaatagactg acacgagacg acttcctggg      600

ccaggtggac gtgcccctta gtcaccttcc gacagaagat ccaaccatgg agcgacccta      660

tacatttaag gactttctcc tcagaccaag aagtcataag tctcgagtta agggattttt      720

gcgattgaaa atggcctata tgccaaaaaa tggaggtcaa gatgaagaaa acagtgacca      780

gagggatgac atggagcatg gatgggaagt tgttgactca aatgactcgg cttctcagca      840

ccaagaggaa cttcctcctc ctcctctgcc tcccgggtgg gaagaaaaag tggacaattt      900

aggccgaact tactatgtca accacaacaa ccggaccact cagtggcaca gaccaagcct      960

gatggacgtg tcctcggagt cggacaataa catcagacag atcaaccagg aggcagcaca     1020

ccggcgcttc cgctcccgca ggcacatcag cgaagacttg gagcccgagc cctcggaggg     1080

cggggatgtc cccgagcctt gggagaccat ttcagaggaa gtgaatatcg ctggagactc     1140

tctcggtctg gctctgcccc caccaccggc ctccccagga tctcggacca gccctcagga     1200

gctgtcagag gaactaagca gaaggcttca gatcactcca gactccaatg gggaacagtt     1260

cagctctttg attcaaagag aaccctcctc aaggttgagg tcatgcagtg tcaccgacgc     1320

agttgcagaa cagggccatc taccaccgcc atcagtggcc tatgtacata ccacgccggg     1380

tctgccttca ggctgggaag aaagaaaaga tgctaagggg cgcacatact atgtcaatca     1440

taacaatcga accacaactt ggactcgacc tatcatgcag cttgcagaag atggtgcgtc     1500

cggatcagcc acaaacagta acaaccatct aatcgagcct cagatccgcc ggcctcgtag     1560

cctcagctcg ccaacagtaa ctttatctgc cccgctggag ggtgccaagg actcacccgt     1620

acgtcgggct gtgaaagaca ccctttccaa cccacagtcc ccacagccat caccttacaa     1680

ctcccccaaa ccacaacaca aagtcacaca gagcttcttg ccacccggct gggaaatgag     1740

gatagcgcca aacggccggc ccttcttcat tgatcataac acaaagacta caacctggga     1800

agatccacgt ttgaaatttc cagtacatat gcggtcaaag acatctttaa accccaatga     1860

ccttggcccc cttcctcctg gctgggaaga aagaattcac ttggatggcc gaacgtttta     1920

tattgatcat aatagcaaaa ttactcagtg ggaagaccca agactgcaga acccagctat     1980

tactggtccg gctgtccctt actccagaga atttaagcag aaatatgact acttcaggaa     2040

gaaattaaag aaacctgctg atatccccaa taggtttgaa atgaaacttc acagaaataa     2100

catatttgaa gagtcctatc ggagaattat gtccgtgaaa agaccagatg tcctaaaagc     2160

tagactgtgg attgagtttg aatcagagaa aggtcttgac tatgggggtg tggccagaga     2220

atggttcttc ttactgtcca aagagatgtt caacccctac tacggcctct ttgagtactc     2280

tgccacggac aactacaccc ttcagatcaa ccctaattca ggcctctgta atgaggatca     2340

tttgtcctac ttcactttta ttggaagagt tgctggtctg gccgtatttc atgggaagct     2400

cttagatggt ttcttcatta gaccatttta caagatgatg ttgggaaagc agataaccct     2460

gaatgacatg gaatctgtgg atagtgaata ttacaactct ttgaaatgga tcctggagaa     2520

tgaccctact gagctggacc tcatgttctg catagacgaa gaaaactttg gacagacata     2580

tcaagtggat ttgaagccca atgggtcaga aataatggtc acaaatgaaa acaaaaggga     2640

atatatcgac ttagtcatcc agtggagatt tgtgaacagg gtccagaagc agatgaacgc     2700

cttcttggag ggattcacag aactacttcc tattgatttg attaaaattt ttgatgaaaa     2760

tgagctggag ttgctcatgt gcggcctcgg tgatgtggat gtgaatgact ggagacagca     2820

ttctatttac aagaacggct actgcccaaa ccaccccgtc attcagtggt tctggaaggc     2880

tgtgctactc atggacgccg aaaagcgtat ccggttactg cagtttgtca cagggacatc     2940

gcgagtacct atgaatggat ttgccgaact ttatggttcc aatggtcctc agctgtttac     3000

aatagagcaa tggggcagtc ctgagaaact gcccagagct cacacatgct ttaatcgcct     3060

tgacttacct ccatatgaaa cctttgaaga tttacgagag aaacttctca tggccgtgga     3120

aaatgctcaa ggatttgaag gggtggatta agcaccctgt gcctcggggg tggttgttct     3180

tcaagcaagt tctgcttgca cttttgcatt tgcctaacag acttttgcag aggcgatggc     3240

agagagcagc tgcaggcatg gtccctggag ccgagccttc accacgcact cgtccaagtt     3300

cggatgcggg aacctggtcc cagcttgagt tcctgccttt cccaccacaa attatcaact     3360

ggttgatgtg tacactaatt acatttcagg aggacttaat gctatttatg ttgtgcctct     3420

gcaggcaaag cccttaataa atattttaca tcctttctaa tgacaatgaa tggaattaat     3480

cactcaacag gtatagtatt acgactcatg tttacttttt aaaatgattt agaccgattt     3540

tcagatttta tttcgttatg attaaagatg tctcatgtac ttggaaaagt gagcattttt     3600

tttttttttg tatttcactt tcataccagg cttaatgtca atgacatttt tatttttgaa     3660

gtactctgac acctccaccc tctactttat tagaattgga aggcaaattt ttgtccaaaa     3720

acctacagac aagtactttg agagaatttc caatataata ttagacataa tgataatttt     3780

ttccatactc agaatgaaaa actggatatt acgtttttgt tttggggttt ttttgtacaa     3840

atttagctaa tagctacagg ctgagagaat tgtaacatag catgacaaat tttgtgttga     3900

cttgaaagga atcacaccat tattccttag aagtaattac atgtgttcta acacatttga     3960

gacagggttg gactcccatt tctcatccga gaaattactt aacccttcct ggcgctgtac     4020

agtcatcttt tattctattt cctctttgct gtttgtagta gagacatttt gaatgaaact     4080

tggcactgct tgattcaaaa ctgtggaaac cagatctgtt tagtctcctg tttgtatgcg     4140

tttgctaatg gtagctaaat aaccagtttt tgttgtaaat gcaccaattc tgaaggcact     4200

ttatgtacta catggaggtc atatctggtt ttgtttttat ttttttatca tgaacattaa     4260

atgtgatgat gatttctttt ccctgcacac atctttccgg tgcaatatct atcaattgtg     4320

aatctggctg ctggtgtata aaaacctgga tgtaaagctg agcctacaga cctgtcctca     4380

ccaactgttt tgtgatttct actcaactac aaagatttat ttaatgtact cttaatctaa     4440

ctgagttttg ttaccaatga cctgttgcat gcttcaatac cgtgtactgc ctgagttgtg     4500

cctcttgtgt gctagattaa aagtgagaca gagacttgac ttgatcctct gagctcaagc     4560

tattgagctg gtagtggcag aggactgagg gtacctgcac agtttgattc ttttccacgt     4620

gtaagtctcc attgcagaat tgtcgtgctt tgagaaaaca cctgaggcag tgtgggagtt     4680

gaacgaccct gctgtccttt ttaacctgtg ttgtcctaga ccctgtcggg gcagtcaggg     4740

gacactagag atttgatctc atgcgagtca tcaataggac aaaaaagttg tggtttgggg     4800

aggtctgttt gttacataaa aaggaccttt cggtgtaaga aattgccgtt tttaccctgc     4860

cctggctggc atgtgagaag ccatggaagg ttgtggttgt aaatgagttg tctaaagggg     4920

tgcagaggcc tgaggtttct aaaagaaggt agatttctac agagctgagt gttggttcct     4980

ttttcttatt ggttgaaaat tacctggtag tgatcagaaa acttagatgc tatgtaacta     5040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaattcc cgctcatgag ttttgactat     5100

tggtgagatg ttttccgcta cagttaacat gacaaatgtc tcagtggcaa aaatcccctt     5160

tttgtaagcc cccatagtct agaggcagtt ttctttttaa gaatcatgcc agagcctgag     5220

tcgagcagta tgctttcttg gtttttgaga gtaattgtgt aattgtagag ggagaaatcc     5280

aattctaacc taagaactgg gattcttctg tcatcttgta aaccgtatat tgaaaaaaac     5340

agaatgtcac taaatgcata ttaagtcaag tattggaaag tataaaagaa aaatcattct     5400

gacaatttct aagccagaag caaacaagaa ttactgaaat ctaccccatg aatacttgga     5460

aggcagtaat tgtgagtgac acctcagttc atcaacccct taataatatc agcttaattt     5520

taatgacaac taaatatgct gaagtgagga tttagtattt tttaaaaaag caaaacaagg     5580

ttcagtagtc ctcagcaatt ctccaagttt ctctctttgc ctaaaatggt catagatctt     5640

gatttctctg aatcgtgatg accacaccca gtcatcttca cagcataatt gcaggtggca     5700

gtaaagagag tgtgctgggt aaggagcagt tgctgggtca ttccttgggc cccgacctgc     5760

ccggggagta gccctggggg agagagggca gtgttgccta tcccagaggt cccagcagtc     5820

acactgctct gcaggccggg ctctctttat agccagagaa atcaccttaa tgcagtctct     5880

ttagttgtct gctgaagctg tagttattat gggccactta catgaggctg agaagtacgt     5940

gccggagctc acacactgcc tgttgcggtt ctcttaacat cagttatcac agctgcctgt     6000

gggtcccggg tatttccatt cctgcccctt gttggcccga ggaaggatgt ggaaagagca     6060

cctggtggga tgaaggtcca acagcctgtg cctctccact gctggccctg gagccggcag     6120

cagtgaggca ttcattgtct gtgttgcggt gtattcccag cttcagtgct cttttccttt     6180

ttgcctgaaa tgtttatgct tctctgcagc cagtcctcta acaaatctca agaacaaagg     6240

taagacactt ggtttttgtt tccaggaccc ttcagaaggt gacatcagat attccctaaa     6300

ttcagacaat gagggataca gagcgacttg gcatgtatta tttctcccat gtaaggacaa     6360

agggacagat tattattgtt atttctgaga cagagtcttg ctctgtagct caggctggag     6420

tgcagtggct caatctcagc tcaccacaac ctctgcctcc tggcttcaag cgattcttct     6480

gcctcagcct ccccgaatag ttgggattac aggcacccac caccacgcct ggctaatttt     6540

tgtattttta gtagagatgg tttcaccatg ctggccaggc tggtcttgaa ctcctgacct     6600

caggtgatcc tcccgcctca gccttccaaa gtgctgggat tacaagcatg agccaccgca     6660

cccggcctca cagtgacaga ttctgagaaa cagcatgcaa aacatttgaa ccattttcta     6720

catctcccat tgttgcatag agagtgtgca ccgctgctat cttgccagat ccacactggt     6780

cctcccgaaa gccaggttca tacacagcaa ctttttaatt attctaacag ttacccatta     6840

acagtcgact cctgtatttc tgagagtctt gtactcacct ctgaaattta aaaacgtata     6900

aagagagcct gggttaatca gttctgcagc ccctacgtga cactgtgcta gttctccttc     6960

ttctgtctcc tccttaccct ggccctgcac ccctgtactt aagagggaga ggtgggaggt     7020

gctgtctggt atcatttgct gcctcgccag tagagggtgc cgctgtgcag ggtaactgcc     7080

cgcctgctcc cttcctgacc tcccctgacc ccgaagatca ctacctctgt cattcaggca     7140

ttggggtaca tcctgataag tcgtgtcaga actgccaatt tcaggactga gatgtgtttt     7200

taaaaaacaa atccttataa actccacttt gtactttaga ttttaaaact ggggaaaaat     7260

gtgatattct ttggaccact tttttaattt atataagcct taatgaacag tgtctataca     7320

tttgcataca cacaccccca ccccagagtg ttctcagtat gtcagagaaa gtgccacagc     7380

attaggacgg gagcttggag aacgttttct agaaaagggt tagcttcctg ttggcatgaa     7440

attttccaag caaacctcat taaacatctg ttgtttgtta aagatgttcc actgaaagca     7500

acgcatgttt caaaggcacg tctttccgtt cgttggtttt ctgtgtgtaa ggagtagcat     7560

tgctgttggc gcctaacctc gcgtgcactg cattctcaac cccgtaccag tgcatcatca     7620

gaagccttcc tcgtgaccat aactctgtgt ctgcagatat gtgttcccgt gtaagccagt     7680

tttccccttt tactcagact gatttcacct agattgtcac ggtttccttc atgttaactt     7740

tgcgtgactt tgttcttcct ttactactct gtatgtaata tatatacata tatacgtaca     7800

tatgctgtcc aaatatattt gtatatattt gtatagcatt tttacacctt tattgagtaa     7860

tctggtttcg aaaggaggtg agagtttagt cccttctgca gttttctcca agctgtgtcc     7920

tgtgaatttc aacccttgga gcctaagaaa accctaggaa gatgatgtta atttgctgtc     7980

atttcctaat tcaggatcta tcatcaaatg aaacatgaaa aaaacagtga cttttaaggt     8040

gaaaagagtt tcaagcattc caaataaatt atcaatgttt cataactttt tattataaac     8100

ccacctccta ataggaagcc aagtactatt tgatacagtg gtaaaaacca aactaccttg     8160

aattttttta aggcaactta tgaataatgc tcattttcac agtcagaata gctttaaaat     8220

atggttgaat ttgatacaca caggaagttt tcttgaagaa caatcctttc gcttttcttt     8280

tttcttgaga gatctaaaga gaaactgtag attgttttcc tgacagcaaa agactaatgt     8340

gacaaaatga agtcattgta aagaagcgat gcaacttgtc aaatatttaa taaagaatta     8400

tggaagctgg aacattttct ac                                              8422


<210>  1593
<211>  3854
<212>  DNA
<213>  homo sapiens

<400>  1593
gcgtgagtga gtacagaagg gaaatgagtg agggggcatg ggatctcaga gaaaatcagg       60

gccctctgag caaagtggaa aggacgaccg ccgcagctcc tcgggccgta gctcgacccc      120

gccttccctt ttgcgcagaa tcctcgcctt ggctgcagca gcgcgctgcc cccactggcc      180

ggcgtgccgt gatcgatcgc aggctgcgtc aggagcctcc cggcgtataa ataggggtgg      240

cagaacggcg ccgagccgca cacagccatc catcctcccc cttccctctc tcccctgtcc      300

tctctctccg ggctcccacc gccgccgcgg gccggggagc caccggccgc caccatgagt      360

tccttcagct acgagccgta ctactcgacc tcctacaagc ggcgctacgt ggagacgccc      420

cgggtgcaca tctccagcgt gcgcagcggc tacagcaccg cacgctcagc ttactccagc      480

tactcggcgc cggtgtcttc ctcgctgtcc gtgcgccgca gctactcctc cagctctgga      540

tcgttgatgc ccagtctgga gaacctcgac ctgagccagg tagccgccat cagcaacgac      600

ctcaagtcca tccgcacgca ggagaaggcg cagctccagg acctcaatga ccgcttcgcc      660

agcttcatcg agcgcgtgca cgagctggag cagcagaaca aggtcctgga agccgagctg      720

ctggtgctgc gccagaagca ctccgagcca tcccgcttcc gggcgctgta cgagcaggag      780

atccgcgacc tgcgcctggc ggcggaagat gccaccaacg agaagcaggc gctccagggc      840

gagcgcgaag ggctggagga gaccctgcgc aacctgcagg cgcgctatga agaggaggtg      900

ctgagccgcg aggacgccga gggccggctg atggaagcgc gcaaaggcgc cgacgaggcg      960

gcgctcgctc gcgccgagct cgagaagcgc atcgacagct tgatggacga aatctctttt     1020

ctgaagaaag tgcacgaaga ggagatcgcc gaactgcagg cgcagatcca gtacgcgcag     1080

atctccgtgg agatggacgt gaccaagccc gacctttccg ccgcgctcaa ggacatccgc     1140

gcgcagtacg agaagctggc cgccaagaac atgcagaacg ctgaggaatg gttcaagagc     1200

cgcttcaccg tgctgaccga gagcgccgcc aagaacaccg acgccgtgcg cgccgccaag     1260

gacgaggtgt ccgagagccg tcgtctgctc aaggccaaga ccctggaaat cgaagcatgc     1320

cggggcatga atgaagcgct ggagaagcag ctgcaggagc tggaggacaa gcagaacgcc     1380

gacatcagcg ctatgcagga cacgatcaac aaattagaaa atgaattgag gaccacaaag     1440

agtgaaatgg cacgatacct aaaagaatac caagacctcc tcaacgtgaa gatggctttg     1500

gatattgaga ttgcagctta caggaaactc ttggaaggcg aggagacccg actcagtttc     1560

accagcgtgg gaagcataac cagtggctac tcccagagct cccaggtctt tggccgatct     1620

gcctacggcg gtttacagac cagctcctat ctgatgtcca cccgctcctt cccgtcctac     1680

tacaccagcc atgtccaaga ggagcagatc gaagtggagg aaaccattga ggctgccaag     1740

gctgaggaag ccaaggatga gcccccctct gaaggagaag ccgaggagga ggagaaggac     1800

aaggaagagg ccgaggaaga ggaggcagct gaagaggaag aagctgccaa ggaagagtct     1860

gaagaagcaa aagaagaaga agaaggaggt gaaggtgaag aaggagagga aaccaaagaa     1920

gctgaagagg aggagaagaa agttgaaggt gctggggagg aacaagcagc taagaagaaa     1980

gattgaaccc ccatttcctt aattatttca ggaataattc tcccgaaatc aggtcaaccc     2040

catcaccaac caaccaacca gttgagttcc agattctatg tgaattaaaa agtcaatata     2100

tgtataattc tgagatgact taggttggac attcaatgtt gtgctatgaa tttcctcttt     2160

atgcagagta tctgtttgct tgcagagtgg ctttctggct tgctgccagc ctgtgcatgg     2220

accacgctta tgagttcagg atctacggca atgtgaatca ttcagatgtt tacaataaaa     2280

aacaccacat gagtaaatga attcactaat gttaatgtta aacttcatgg aaaaatagtc     2340

ctttgaacct tcggtggtta gcaattaaag accctgagtt atgtgcaata aatagtaaat     2400

aaagttatac cgaatgatgt attttttgct gtggttgtta cttaattaaa ataccttaaa     2460

gatggcacca atataaagta tataccagtg gactattgac ctccaatttt ttaaaaagtt     2520

gaaattttaa caattaccaa tacttttttt tcttccttca attggaaatt ctgagggata     2580

cagttatgtc atgattactt gtgaaatctc tccccacaaa aattttactg ataataaaca     2640

tgagtaaatg agaaagtcta taaataacaa tagactttgc ctcataacac gtgttgtgtt     2700

aggttttggg atggctttct agggagcaat tctgaaatta cttgacagat acactcttta     2760

tggtaaacag gtcatttcag agtctagagt gctaaccatt acactatgga accatgataa     2820

ataggtcatt tcaaactgat atgtcacaat gcaatatgga tagaatatga atcccataca     2880

ttcatcccta taactgcatt ttaaaatata gtctaaatat catgggagga ggttaaaacc     2940

tgagaacatg gtacaataag aaggaataat tttttatcta tatataattt caggagaagg     3000

gattaaaact accaaaggtt atttgccact ccactgcaaa catgttgcct gcaatcctga     3060

gctcatgatt tagtgtgttg ttaagcgtaa ttctgttgcc tcaagtaaat accacttaat     3120

gctacacatt tttaaacctt taaaagctac agacacaagt aatgaaatta tgagtcactt     3180

aaggggggag gtaatatgct tgtatgttac attgacattg ctctgcatgt ctctactggg     3240

agatatttgg atttcaatga tagcttgact ggttggacat tgcatcaaat acacgcccca     3300

tgtatccttt ctgtcgtaaa gttaagaacg ctcttgcatt tgatgtggaa taaatataga     3360

tgatattact atctgctatt ctgcctttgt tctgaaacaa ttgctttgtc agctaatttc     3420

attcaatatt tgttttttag acgatctcta taagttatta atttaacctg aaaccaaagt     3480

ggtctccatt taaagttact taatcccttt gtaccaccta tttctagtta aatatatgtt     3540

gctatgcaaa taggtaaagt gcttccttgc catgatggta atggattgga actatgaagg     3600

ctctcagtgt attggcttct gtaaagatga ggcgtctcct cagaaacaaa acttttcaca     3660

tttctgctta ctagacctgg gttgatgtac atggtaagtc tcaaacagat gcaagctatg     3720

tgcaaaaagt aactttagcc aaatggaaat agctggatgc tttgagaatt acttggttga     3780

agtaagaaaa ctgtaccatc ctctatcctg tgtgccataa taaaatagta aaaaacctaa     3840

aaaaaaaaaa aaaa                                                       3854


<210>  1594
<211>  3854
<212>  DNA
<213>  homo sapiens

<400>  1594
gcgtgagtga gtacagaagg gaaatgagtg agggggcatg ggatctcaga gaaaatcagg       60

gccctctgag caaagtggaa aggacgaccg ccgcagctcc tcgggccgta gctcgacccc      120

gccttccctt ttgcgcagaa tcctcgcctt ggctgcagca gcgcgctgcc cccactggcc      180

ggcgtgccgt gatcgatcgc aggctgcgtc aggagcctcc cggcgtataa ataggggtgg      240

cagaacggcg ccgagccgca cacagccatc catcctcccc cttccctctc tcccctgtcc      300

tctctctccg ggctcccacc gccgccgcgg gccggggagc caccggccgc caccatgagt      360

tccttcagct acgagccgta ctactcgacc tcctacaagc ggcgctacgt ggagacgccc      420

cgggtgcaca tctccagcgt gcgcagcggc tacagcaccg cacgctcagc ttactccagc      480

tactcggcgc cggtgtcttc ctcgctgtcc gtgcgccgca gctactcctc cagctctgga      540

tcgttgatgc ccagtctgga gaacctcgac ctgagccagg tagccgccat cagcaacgac      600

ctcaagtcca tccgcacgca ggagaaggcg cagctccagg acctcaatga ccgcttcgcc      660

agcttcatcg agcgcgtgca cgagctggag cagcagaaca aggtcctgga agccgagctg      720

ctggtgctgc gccagaagca ctccgagcca tcccgcttcc gggcgctgta cgagcaggag      780

atccgcgacc tgcgcctggc ggcggaagat gccaccaacg agaagcaggc gctccagggc      840

gagcgcgaag ggctggagga gaccctgcgc aacctgcagg cgcgctatga agaggaggtg      900

ctgagccgcg aggacgccga gggccggctg atggaagcgc gcaaaggcgc cgacgaggcg      960

gcgctcgctc gcgccgagct cgagaagcgc atcgacagct tgatggacga aatctctttt     1020

ctgaagaaag tgcacgaaga ggagatcgcc gaactgcagg cgcagatcca gtacgcgcag     1080

atctccgtgg agatggacgt gaccaagccc gacctttccg ccgcgctcaa ggacatccgc     1140

gcgcagtacg agaagctggc cgccaagaac atgcagaacg ctgaggaatg gttcaagagc     1200

cgcttcaccg tgctgaccga gagcgccgcc aagaacaccg acgccgtgcg cgccgccaag     1260

gacgaggtgt ccgagagccg tcgtctgctc aaggccaaga ccctggaaat cgaagcatgc     1320

cggggcatga atgaagcgct ggagaagcag ctgcaggagc tggaggacaa gcagaacgcc     1380

gacatcagcg ctatgcagga cacgatcaac aaattagaaa atgaattgag gaccacaaag     1440

agtgaaatgg cacgatacct aaaagaatac caagacctcc tcaacgtgaa gatggctttg     1500

gatattgaga ttgcagctta caggaaactc ttggaaggcg aggagacccg actcagtttc     1560

accagcgtgg gaagcataac cagtggctac tcccagagct cccaggtctt tggccgatct     1620

gcctacggcg gtttacagac cagctcctat ctgatgtcca cccgctcctt cccgtcctac     1680

tacaccagcc atgtccaaga ggagcagatc gaagtggagg aaaccattga ggctgccaag     1740

gctgaggaag ccaaggatga gcccccctct gaaggagaag ccgaggagga ggagaaggac     1800

aaggaagagg ccgaggaaga ggaggcagct gaagaggaag aagctgccaa ggaagagtct     1860

gaagaagcaa aagaagaaga agaaggaggt gaaggtgaag aaggagagga aaccaaagaa     1920

gctgaagagg aggagaagaa agttgaaggt gctggggagg aacaagcagc taagaagaaa     1980

gattgaaccc ccatttcctt aattatttca ggaataattc tcccgaaatc aggtcaaccc     2040

catcaccaac caaccaacca gttgagttcc agattctatg tgaattaaaa agtcaatata     2100

tgtataattc tgagatgact taggttggac attcaatgtt gtgctatgaa tttcctcttt     2160

atgcagagta tctgtttgct tgcagagtgg ctttctggct tgctgccagc ctgtgcatgg     2220

accacgctta tgagttcagg atctacggca atgtgaatca ttcagatgtt tacaataaaa     2280

aacaccacat gagtaaatga attcactaat gttaatgtta aacttcatgg aaaaatagtc     2340

ctttgaacct tcggtggtta gcaattaaag accctgagtt atgtgcaata aatagtaaat     2400

aaagttatac cgaatgatgt attttttgct gtggttgtta cttaattaaa ataccttaaa     2460

gatggcacca atataaagta tataccagtg gactattgac ctccaatttt ttaaaaagtt     2520

gaaattttaa caattaccaa tacttttttt tcttccttca attggaaatt ctgagggata     2580

cagttatgtc atgattactt gtgaaatctc tccccacaaa aattttactg ataataaaca     2640

tgagtaaatg agaaagtcta taaataacaa tagactttgc ctcataacac gtgttgtgtt     2700

aggttttggg atggctttct agggagcaat tctgaaatta cttgacagat acactcttta     2760

tggtaaacag gtcatttcag agtctagagt gctaaccatt acactatgga accatgataa     2820

ataggtcatt tcaaactgat atgtcacaat gcaatatgga tagaatatga atcccataca     2880

ttcatcccta taactgcatt ttaaaatata gtctaaatat catgggagga ggttaaaacc     2940

tgagaacatg gtacaataag aaggaataat tttttatcta tatataattt caggagaagg     3000

gattaaaact accaaaggtt atttgccact ccactgcaaa catgttgcct gcaatcctga     3060

gctcatgatt tagtgtgttg ttaagcgtaa ttctgttgcc tcaagtaaat accacttaat     3120

gctacacatt tttaaacctt taaaagctac agacacaagt aatgaaatta tgagtcactt     3180

aaggggggag gtaatatgct tgtatgttac attgacattg ctctgcatgt ctctactggg     3240

agatatttgg atttcaatga tagcttgact ggttggacat tgcatcaaat acacgcccca     3300

tgtatccttt ctgtcgtaaa gttaagaacg ctcttgcatt tgatgtggaa taaatataga     3360

tgatattact atctgctatt ctgcctttgt tctgaaacaa ttgctttgtc agctaatttc     3420

attcaatatt tgttttttag acgatctcta taagttatta atttaacctg aaaccaaagt     3480

ggtctccatt taaagttact taatcccttt gtaccaccta tttctagtta aatatatgtt     3540

gctatgcaaa taggtaaagt gcttccttgc catgatggta atggattgga actatgaagg     3600

ctctcagtgt attggcttct gtaaagatga ggcgtctcct cagaaacaaa acttttcaca     3660

tttctgctta ctagacctgg gttgatgtac atggtaagtc tcaaacagat gcaagctatg     3720

tgcaaaaagt aactttagcc aaatggaaat agctggatgc tttgagaatt acttggttga     3780

agtaagaaaa ctgtaccatc ctctatcctg tgtgccataa taaaatagta aaaaacctaa     3840

aaaaaaaaaa aaaa                                                       3854


<210>  1595
<211>  864
<212>  DNA
<213>  homo sapiens

<400>  1595
gagccattga ttggtcgacg cccccagagg gttacaattc aaacgcgggc gggcgggccc       60

gcagtcctgc agttgcagtc gtgttctccg agttcctgtc tctctgccaa cgccgcccgg      120

atggcttccc aaaaccgcga cccagccgcc actagcgtcg ccgccgcccg taaaggagct      180

gagccgagcg ggggcgccgc ccggggtccg gtgggcaaaa ggctacagca ggagctgatg      240

accctcatga tgtctggcga taaagggatt tctgccttcc ctgaatcaga caaccttttc      300

aaatgggtag ggaccatcca tggagcagct ggaacagtat atgaagacct gaggtataag      360

ctctcgctag agttccccag tggctaccct tacaatgcgc ccacagtgaa gttcctcacg      420

ccctgctatc accccaacgt ggacacccag ggtaacatat gcctggacat cctgaaggaa      480

aagtggtctg ccctgtatga tgtcaggacc attctgctct ccatccagag ccttctagga      540

gaacccaaca ttgatagtcc cttgaacaca catgctgccg agctctggaa aaaccccaca      600

gcttttaaga agtacctgca agaaacctac tcaaagcagg tcaccagcca ggagccctga      660

cccaggctgc ccagcctgtc cttgtgtcgt ctttttaatt tttccttaga tggtctgtcc      720

tttttgtgat ttctgtatag gactctttat cttgagctgt ggtatttttg ttttgttttt      780

gtcttttaaa ttaagcctcg gttgagccct tgtatattaa ataaatgcat ttttgtcctt      840

ttttagacaa aaaaaaaaaa aaaa                                             864


<210>  1596
<211>  810
<212>  DNA
<213>  homo sapiens

<400>  1596
gagccattga ttggtcgacg cccccagagg gttacaattc aaacgcgggc gggcgggccc       60

gcagtcctgc agttgcagtc gtgttctccg agttcctgtc tctctgccaa cgccgcccgg      120

atggcttccc aaaaccgcga cccagccgcc actagcgtcg ccgccgcccg taaaggagct      180

gagccgagcg ggggcgccgc ccggggtccg gtgggcaaaa ggctacagca ggagctgatg      240

accctcatga tgtctggcga taaagggatt tctgccttcc ctgaatcaga caaccttttc      300

aaatgggtag ggaccatcca tggagcagct ggaacagcag tggggagcat cagaaccagc      360

tcaacagttt gtctactgtc cggtcccaga gaaactcaag attctagcaa gccccttgtg      420

tggggcttgg gttgggacat gaggctgctg ctggagctta ctctgcaact gtttctccaa      480

atgccagaac ccaacattga tagtcccttg aacacacatg ctgccgagct ctggaaaaac      540

cccacagctt ttaagaagta cctgcaagaa acctactcaa agcaggtcac cagccaggag      600

ccctgaccca ggctgcccag cctgtccttg tgtcgtcttt ttaatttttc cttagatggt      660

ctgtcctttt tgtgatttct gtataggact ctttatcttg agctgtggta tttttgtttt      720

gtttttgtct tttaaattaa gcctcggttg agcccttgta tattaaataa atgcattttt      780

gtcctttttt agacaaaaaa aaaaaaaaaa                                       810


<210>  1597
<211>  1005
<212>  DNA
<213>  homo sapiens

<400>  1597
gaggattggg aggaactcga cctactccgc taacccagtg gcctgagcca atcacaaaga       60

ggattggagc ctcactcgag cgctccttcc cttctcctct ctctgtgaca gcctcttgga      120

aagagggaca ctggaggggt gtgtttgcaa tttaaatcac tggatttttg cccaccctct      180

ttccaaataa gaaggcagga gctgcttgct gaggtgtaaa gggtcttctg agctgcagtg      240

gcaattagac cagaagatcc ccgctcctgt ctctaaagag gggaaagggc aaggatggtg      300

gaggctttct gtgctacctg gaagctgacc aacagtcaga actttgatga gtacatgaag      360

gctctaggcg tgggctttgc cactaggcag gtgggaaatg tgaccaaacc aacggtaatt      420

atcagtcaag aaggagacaa agtggtcatc aggactctca gcacattcaa gaacacggag      480

attagtttcc agctgggaga agagtttgat gaaaccactg cagatgatag aaactgtaag      540

tctgttgtta gcctggatgg agacaaactt gttcacatac agaaatggga tggcaaagaa      600

acaaattttg taagagaaat taaggatggc aaaatggtta tgacccttac ttttggtgat      660

gtggttgctg ttcgccacta tgagaaggca taaaaatgtt cctggtcggg gcttggaaga      720

gctcttcagt ttttctgttt cctcaagtct cagtgctatc ctattacaac atggctgatc      780

attaattaga aggttatcct tggtgtggag gtggaaaatg gtgatttaaa aacttgttac      840

tccaagcaac ttgcccaatt ttaatctgaa aatttatcat gttttataat ttgaattaaa      900

gttttgtccc cccccccctt ttttttataa acaagtgaat acattttata atttcttttg      960

gaatgtaaat caaatttgaa taaaaatctt acacgtgaaa aaaaa                     1005


<210>  1598
<211>  3488
<212>  DNA
<213>  homo sapiens

<400>  1598
ctgcctcagg aagcttggct tcccctccca tggggaagtg ctggaatcca ctcttgcctg       60

accctcccat aagaaacaag ggaaattcct ttacgtgagc cgccttgctc agaacaaagc      120

ttggcgtgtt tcttattcct catcaatctg acaaaatggg tatttatttg tgcctctcaa      180

gcgtgtggct tggacatgat gttccgcatc gtggaagtgg ccgtgcacca agtggaatat      240

ctgttactat agtaacagtt cctttttatt gataccagaa taaacaggaa tgcaaaggct      300

gtctcacttg ttggcacatt tcagcagcct ccgttcccag gggtttaaga accgccctct      360

agaggcagcc ctccttgcta gtctgggact tcccggtgga gtgaggaacc cagcaacacg      420

ctcctgactt cccttcccaa ggactcgacc tgagaaggac acagcagtct ctgaatttca      480

tgctctcctc tttgatgtga agaaaatgaa aagctgaaca gttgtggaac tgtggataga      540

gttagacaat aaggccgcca tgtactcgga gatccagagg gagcgggcag acattggggg      600

cctgatggcc cggccagaat acagagagtg gaatccggag ctcatcaagc ccaagaagct      660

gctgaacccc gtgaaggcct ctcggagtca ccaggagctc caccgggagc tgctcatgaa      720

ccacagaagg ggccttggtg tggacagcaa gccagagctg cagcgtgtcc tagagcaccg      780

ccggcggaac cagctcatca agaagaagaa ggaggagctg gaagccaagc ggctgcagtg      840

cccctttgag caggagctgc tgagacggca gcagaggctg aaccagctgg aaaaaccacc      900

agagaaggaa gaggatcacg cccccgagtt tattaaagtc agggaaaacc tgcggagaat      960

tgccacactg accagcgaag agagagagct gtagggccag ctgccgggct caggccactg     1020

cccaccctgg cctggacagc ctccttcagc ccttctgtac ctggcagccc tgggccccag     1080

gccctgggac gtctgtgatg ttcccacctg cttctgtaga aatgtgtcac cccagagggc     1140

ctggctctcc ctgggaggct ggggccccta agctcctagg ttttccttcc aagcacccag     1200

ccctcctgct ccaagaggga taacctgcac ccctccctgc aaggggttca gagcccagca     1260

caggagcttt ctctggcaga attgaggagg aagaggtggc cctctgactt gacaagcctt     1320

ctgttctgcc caggccttcc caccaggaat ctccgaggct ccccagggcc ccgcttctcc     1380

gtacacccca gctcctaggt ctcagagaac tcccccacct gtggttttac ctgcagccag     1440

cagagcttag cttcaaggac acctgccttc aaagccactg aggggaggaa gggcagggca     1500

gactgcagat ggccttgttg ctggcatccc ggccaggtgg gcggggacta acaaagacag     1560

ctgtttaggg tcttctcccc tcacccatgc tttcatcatc ccctccgcac agcctccccg     1620

tccaggcctt ctaaccacac ctacccaggg ctgccgcatt cctgcactca gaagtctgca     1680

gcggtgcctc acaaacttga ttgtgcataa aaatcactgg ggatcttgtt aatacagctt     1740

ctaactcaat agatctggga gatcctgcat ttctaacaag ctcccaggta aggcggaggc     1800

tgctggtgtg aggaccatgc tgtgagcagc agggcgagag tgcccagggc tgatatatat     1860

tggaaatatc acccctgaag ccatcgctgg cccccacctc ctgtggactg atgccccagg     1920

gattcccacc ccacttctgc aaccccaggt atccttcatt atccacccca tcccagactc     1980

ccaccccagg gattgcccgt gaagactttg gcctagcaaa ttgtgttggt tatgtgagtg     2040

ttgttttaat cagagatgta catgattgcc aatctgcatt tcttaccagt gtgaccacac     2100

tgttacgatg caattctagc caaaaaaaaa aaaaaaaaaa aaaaaatttt ttttttttac     2160

tttttcctag tcttatggaa agcaaatata caatgatttt cagtaggctt ctggaataga     2220

aacagtggtt tgaagacccc actgccacct ttatggactg gcccctttga gtctgaatcc     2280

ccggcctctg tcacctgaga cccaacccct agctgggcca actccagtga attcacccat     2340

ttttcttctt cagaaggcct ttcctgtgtg agacccacat attttaacct tttgctccta     2400

tcccattttt aaagaattag agaataaacc aggcctgttt cttttcccct gaaatccctg     2460

cctctggctt cctaaaccca tcatctaagg tgacagagca gtgctggaat agcatctcct     2520

ttcactttcc caaaactgcc acagatagct gccactggca tgctctttga ttcctggaag     2580

caaacgtggg actgtcggag gaaagggatt gttctggtct tactcataac tgggtggttt     2640

gagggtgact gaagtcgtgc ttttcctgtg tgtgctgcca gcacagggct gtaaatgcag     2700

atattgcgcc tgtgtgcgtg tgtataagtc aagctccaag aggctcctga atgtgactgg     2760

cgtgctgaga atgtgtttac gctgtttaat gtctgccagg tgagggttac actgaagatg     2820

cacaatccct aaaataaaga tcaccacttc cccaaagaag cagccctcgg gtccatgtgt     2880

tgttcagaca tgtgaagaga agcaagacag agggtctcag atggacgagg gctctccaag     2940

ggaatgcctg gggattcacc cagtggtccc cagaggtgct ccatggaggc aacaagtcat     3000

tccatgaagc cccagaggta gaagggacct caagcaccac gccctccagg gcagccgtgc     3060

agacgacctt ggttcacttt tcaggggtcg tcccaactct gtatctccag ccactccaac     3120

tgtggaggct gtaaatccag attttcactg ttccagtctc ctttgcagct taggatggct     3180

atgtgatcag gtgtggccaa tgaaattgaa gaggaagtct acctgggctt ctgggaaagc     3240

ttttccaata aaagacacag gcatggctaa cacctccctg ggcctcttct tcctaccttg     3300

attgagggtg tgatgcctgg agccacagca gccactttgc taccatgaca aaaaggccaa     3360

gagaatcaca gagtcattga ccctatcatt atttcaccaa gccaatacca gccgccatcc     3420

ttctccagaa ttcttgtaaa taaaataaat ccctctttgt ttaaaccatt aaaaaaaaaa     3480

aaaaaaaa                                                              3488


<210>  1599
<211>  4166
<212>  DNA
<213>  homo sapiens

<400>  1599
gttggaggtg gagtagttca gaatcaactg acgcagccgg gaattgagct ttgcaaagcc       60

acttgcaagg aagggaagca tctgcccaac cctcccccac cgcgcgccct ggatcctctg      120

cctgccccct cccccgtgac gtcaccctag tcctgtcccg gggagcctgc aaagcctctc      180

agattcaaac tgctagacgc actgctgcca ccgccaccga attggaaacg cgcgcccagg      240

ctccgtcgtc gccttcgccc gccgaccggg ccagccggct ctccgacctc cctacagaat      300

cgcaccccag tccctccctg gcagctcggc ttccctcagc tccaactctt ctcttccgct      360

cctgcctcct gtcggatttt taatttctgc gcacccccag tcaaattaaa tcaaccaaca      420

aaaagcaggg catcccccct ggaagcagcg tcttatttta ccttgttctc ccacttcctg      480

aagatgctaa actcctggtg gactgcagag gagagggatt cagtcttctc ctgatgtcga      540

ttgcgatttc tgctgggagc tcaagacggg cgagctgccc gagatctctt cgagataccc      600

caggggagga ggagatgggc aggatttagt aggacaactc ggttactaat gacttggcgg      660

ctggctgcga ccccccggga aatcaggtgc aagcatgttt gcctgtaggt acctgagttg      720

acaccgaagg tgcctaaaga tgctgagcgg cgtttggttc ctcagtgtgt taaccgtggc      780

cgggatctta cagacagaga gtcgcaaaac tgccaaagac atttgcaaga tccgctgtct      840

gtgcgaagaa aaggaaaacg tactgaatat caactgtgag aacaaaggat ttacaacagt      900

tagcctgctc cagccccccc agtatcgaat ctatcagctt tttctcaatg gaaacctctt      960

gacaagactg tatccaaacg aatttgtcaa ttactccaac gcggtgactc ttcacctagg     1020

taacaacggg ttacaggaga tccgaacggg ggcattcagt ggcctgaaaa ctctcaaaag     1080

actgcatctc aacaacaaca agcttgagat attgagggag gacaccttcc taggcctgga     1140

gagcctggag tatctccagg ccgactacaa ttacatcagt gccatcgagg ctggggcatt     1200

cagcaaactt aacaagctca aagtgctcat cctgaatgac aaccttctgc tttcactgcc     1260

cagcaatgtg ttccgctttg tcctgctgac ccacttagac ctcaggggga ataggctaaa     1320

agtaatgcct tttgctggcg tccttgaaca tattggaggg atcatggaga ttcagctgga     1380

ggaaaatcca tggaattgca cttgtgactt acttcctctc aaggcctggc tagacaccat     1440

aactgttttt gtgggagaga ttgtctgtga gactcccttt aggttgcatg ggaaagacgt     1500

gacccagctg accaggcaag acctctgtcc cagaaaaagt gccagtgatt ccagtcagag     1560

gggcagccat gctgacaccc acgtccaaag gctgtcacct acaatgaatc ctgctctcaa     1620

cccaaccagg gctccgaaag ccagccggcc gcccaaaatg agaaatcgtc caactcctcg     1680

agtgactgtg tcaaaggaca ggcaaagttt tggacccatc atggtgtacc agaccaagtc     1740

tcctgtgcct ctcacctgtc ccagcagctg tgtctgcacc tctcagagct cagacaatgg     1800

tctgaatgta aactgccaag aaaggaagtt cactaatatc tctgacctgc agcccaaacc     1860

gaccagtcca aagaaactct acctaacagg gaactatctt caaactgtct ataagaatga     1920

cctcttagaa tacagttctt tggacttact gcacttagga aacaacagga ttgcagtcat     1980

tcaggaaggt gcctttacaa acctgaccag tttacgcaga ctttatctga atggcaatta     2040

ccttgaagtg ctgtaccctt ctatgtttga tggactgcag agcttgcaat atctctattt     2100

agagtataat gtcattaagg aaattaagcc tctgaccttt gatgctttga ttaacctaca     2160

gctactgttt ctgaacaaca accttcttcg gtccttacct gataatatat ttggggggac     2220

ggccctaacc aggctgaatc tgagaaacaa ccatttttct cacctgcccg tgaaaggggt     2280

tctggatcag ctcccggctt tcatccagat agatctgcag gagaacccct gggactgtac     2340

ctgtgacatc atggggctga aagactggac agaacatgcc aattcccctg tcatcattaa     2400

tgaggtgact tgcgaatctc ctgctaagca tgcaggggag atactaaaat ttctggggag     2460

ggaggctatc tgtccagaca gcccaaactt gtcagatgga accgtcttgt caatgaatca     2520

caatacagac acacctcggt cgcttagtgt gtctcctagt tcctatcctg aactacacac     2580

tgaagttcca ctgtctgtct taattctggg attgcttgtt gttttcatct tatctgtctg     2640

ttttggggct ggtttattcg tctttgtctt gaaacgccga aagggagtgc cgagcgttcc     2700

caggaatacc aacaacttag acgtaagctc ctttcaatta cagtatgggt cttacaacac     2760

tgagactcac gataaaacag acggccatgt ctacaactat atccccccac ctgtgggtca     2820

gatgtgccaa aaccccatct acatgcagaa ggaaggagac ccagtagcct attaccgaaa     2880

cctgcaagag ttcagctata gcaacctgga ggagaaaaaa gaagagccag ccacacctgc     2940

ttacacaata agtgccactg agctgctaga aaagcaggcc acaccaagag agcctgagct     3000

gctgtatcaa aatattgctg agcgagtcaa ggaacttccc agcgcaggcc tagtccacta     3060

taacttttgt accttaccta aaaggcagtt tgccccttcc tatgaatctc gacgccaaaa     3120

ccaagacaga atcaataaaa ccgttttata tggaactccc aggaaatgct ttgtggggca     3180

gtcaaaaccc aaccaccctt tactgcaagc taagccgcaa tcagaaccgg actacctcga     3240

agttctggaa aaacaaactg caatcagtca gctgtgaagg gaaatcattt acaaccctaa     3300

ggcatcagag gatgctgctc cgaactgttg gaaacaagga cattagcttt tgtgtttgtt     3360

tttgttctcc ctttcccagt gttaatgggg gactttgaaa atgtttggga gataggatga     3420

agtcatgatt ttgcttttgc aagttttcct ttaaattatt tctctctcgc tctcctcccc     3480

tccttttttt tttttttttt tttttctttt tcccttctct tcttaggaac catcagtgga     3540

catgaatgtt tctacaatgc atttcttcat agattttgtt tatggttttg tttctttttt     3600

cttctttgtt tttcagtgtg ggagtgggaa gaggagatta tagtgactga agaaagaata     3660

ggcaaacttt tcaaatgaaa atggatattt agtgtatttt gtagaagatc tccaaagatc     3720

ttttgtgact acaacttctt ttgtaaataa tgatatatgg tatttccatc gtcagttacc     3780

gagtatagcc actgggtatc actactttgt gttaaagtgc cttcgcactt taagtacatt     3840

acttaaatgt tgcttttagc tttgataaat tgaaaatatt ttaatgtgtt gtatttttga     3900

aattgaaaac actgtaaaat agattgatgt gtcagctata ttaagtcaac gtacagtttg     3960

cttgagttat agaaaccagc ctgtcatcaa atgattctag ttctaggact ttgtaggctt     4020

aactataaaa tatttccttt cctctgggtt taagtgattt tatttaagtc aactaagggg     4080

atttaacagt ggactagagg taataagcca cctcagtcag gattaataat tcattaataa     4140

aatatattta acccaaaaaa aaaaaa                                          4166


<210>  1600
<211>  4359
<212>  DNA
<213>  homo sapiens

<400>  1600
gggggccccg ccgccccagc agcccaggac agccccctct ccccgccccc agccccctcc       60

cccggcgcgg ccatggatgt gaccagcagc tcgggcggcg gcggcgaccc ccggcagatc      120

gaggagacca agccgctgct ggggggcgac gtgtcggccc ccgaaggcac gaagatgggc      180

gccgtgccct gccgccgggc tcttctgctt tgcaacggga tgaggtacaa actgctgcag      240

gagggcgaca ttcaggtctg tgtcatccgg cacccgcgga cctttctcag caagatcctc      300

acctcgaaat tcctgaggcg ctgggagccg caccacctaa cgctggccga caacagcctg      360

gcgtccgcca cgccaactgg gtacatggaa aactcagtct cctacagcgc aattgaagac      420

gttcagctgc tgtcctggga gaatgccccg aagtactgtt tacagctcac gattcctggg      480

ggaactgtct tactgcaggc tgccaatagc tacctgcgag accagtggtt ccattctctg      540

caatggaaga aaaagattta caaatataag aaagtgctga gtaacccaag ccgctgggaa      600

gttgtcttga aagagatccg gaccctggtg gacatggccc tgacatcccc cctgcaggat      660

gactccatca accaggcccc actggaaatc gtctcgaaac tgctctcaga gaacacaaac      720

ttgaccaccc aggagcatga aaacatcatt gtggcaatcg ctcctttgct ggaaaacaac      780

cacccaccac cagatctctg tgaattcttt tgcaagcact gcagagagcg gccccggtcc      840

atggtggtca tcgaggtgtt cacccccgtg gtgcagcgaa tcctcaagca taacatggac      900

tttgggaagt gcccgcgact gaggctgttt actcaggagt acatccttgc cttgaacgag      960

ctcaacgcgg ggatggaagt ggtgaagaag ttcattcaga gcatgcacgg ccccacaggg     1020

cactgccccc acccccgggt cctgcccaac ctggtggccg tgtgcctggc tgccatctac     1080

tcctgctatg aagagttcat caacagccgc gacaattccc caagcctgaa ggaaatccgg     1140

aacggctgcc agcagccgtg cgaccggaag cccactttac ctctgcgcct tctgcacccc     1200

agcccggacc tggtgtctca ggaagccacg ctgtctgagg cccggctcaa gtcggtggtc     1260

gtggcctcca gtgagatcca cgtggaggtg gaacgcacca gcactgccaa gccggcgctg     1320

acggccagcg caggcaacga cagcgagccc aacctcatcg actgcctcat ggtcagcccc     1380

gcctgcagca ccatgagcat cgagctgggc ccccaggccg accgcacgct cggctgctac     1440

gtggaaatcc tcaagctgct gtcagactat gatgactgga gaccgtctct ggccagtttg     1500

cttcaaccca ttccattccc caaagaagct ctcgcacatg agaagttcac caaggaactg     1560

aagtacgtga ttcagaggtt cgccgaagac cccaggcaag aggtccactc atgcctgctg     1620

agcgtgcggg ccggcaaaga tggctggttc cagctctaca gccccggagg ggtggcctgc     1680

gacgatgacg gggagctgtt cgccagcatg gtgcacatcc tcatgggctc ctgttacaag     1740

accaaaaaat tcctgctctc cctggcagaa aacaagctgg gtccctgcat gctcctggca     1800

ctgaggggga accagaccat ggtggagatc ctgtgcttga tgctggaata caacatcatc     1860

gacaacaacg acacccaact gcagatcatc tcaaccctgg agagcacaga cgtggggaag     1920

cgcatgtacg agcagctgtg tgaccggcag cgggagctga aggagctgca aaggaaaggc     1980

gggcccacca ggctaacact gccctccaag tccacagacg ctgacttggc tcgtttgctg     2040

agctccggct ccttcggaaa cctggagaac ctcagtttgg ccttcaccaa tgtaaccagt     2100

gcctgcgccg agcacctcat caaactgcct tcgctcaagc agctgaacct gtggtccact     2160

cagtttggag acgctggcct tcggctcctg tcggaacacc tcaccatgct ccaggtgctg     2220

aacctgtgcg agaccccggt cacagacgct ggcctgctgg ccctgagctc catgaagagt     2280

ctctgcagtt taaacatgaa cagcaccaag ctctcagctg acacctacga agatctgaag     2340

gccaagcttc ccaatttgaa ggaagtggac gtccgctaca ccgaagcctg gtgaagctcc     2400

cagctcaagg caggaagacg tttgcaaccg cgacaaaata actcttgact aacagccgca     2460

gagcagccgg tcctggggtc ccaccctggt gccctggctg tgagatagat ggggagtctt     2520

tctgggggcg gaggggggag ggggtgggga gggggcccac aagcacgccc agcccccgcc     2580

gaattctttt agcttcgtaa ttggaacctt tgacctgatc taaagtggac tttgtagcaa     2640

caagaggagc atcagcgggt cggggagggg tttgggggtg ggctgggggg tgggggaccc     2700

tttgtggatt ttctttgcct ttgtgtttga tgccgtcgtg tgggaaaagt caactccgat     2760

gccaccattg cgggccggac gaaggatgct ttcttcctag aggctccgag ctgagctgcg     2820

aactcgcccc ccgcccttgg gacaagaaga cccagtcaca tcactgcacc cgtcctgtgt     2880

cctcaccatt gctatgcaaa gtgattcttg ttgtacataa gatttaaata atgcacctat     2940

ttaagacatg ttgacaaatt gcgggtctgg gacccgcctc ttatttatga agtctttgac     3000

cgtccccccc gcccgacccc accgccctcc cgcccccacc tggcgtgtag tactgtataa     3060

accagtcagc tgtcgggtta gtggtagtat tattgttatt tttttaaagg aaacaaacag     3120

acaacaaaaa gaagaaaaaa aaaaagaacc tccttggaaa aattaattgc tttttcgtaa     3180

tggattctct atgctaatgc tctctcgtct gtctgtctgt ctgcccactc ccccacccac     3240

cactgtgcgt ttctgatttc caaatgtctc caactccctc acgaggtggg gctcaggctg     3300

gaggaggagg gattaagatc cccttgctcc actaaggccc aagctctttc tctcggcacc     3360

ttttagactt gaatgggagg ctgctaaccc gccctctcca gtccaccccg gtaaaagagc     3420

tgttccccac ccccagggag ctcctgtccc tgtcagcctt tgctgtcccc tgtccccaac     3480

ggagactctg tcacccctgg gctccccctg ccatcgtgtg cttcacgtgg ccccatgcat     3540

gcccgcctct ctgcatggtc tcttgggaaa agagagatgt gtcgcctccg ccagtccgac     3600

tgccctcccc accccacccc cgccaccccc cacatgtgac cactgcaacg aagacactcc     3660

ttctgtcccc acctgctccg aagacaaacc aacctccgtt tcttttataa acagtcggct     3720

ttttcttaat aagccctcac tgtacagaac agcccgttga tggtttattt ggggtccccc     3780

tctcccccca gccctttttt ctgttggttt agcacaaata cttccctcct ccggcacctc     3840

caaacctacc ccacagtcag tgtacttgtt ttatatatat ttaatcttat tcaatggaaa     3900

ccatgctttt gtcgttttat actttgctag gtagacttta ttaccccccc actatgccct     3960

cattttttta aaaaaggaaa aaaaaaagaa actgggttcc agtcttaatt cattttccgt     4020

gccaggtttt atttcgtgtg tgtgtgagtg tgttctgttt tgtgttttgt tttttgttgt     4080

tgtttttagt tgtttggttt tcttttcttt cccccctccg gtcccatact tcacagcact     4140

ctggtgcggg aagaagcaga agcaaaaaaa ataaaaataa aaaaataaat aaaaataaaa     4200

aaaataaaaa aggaaaaaaa aaaaagaaga aacaagacat gccacctttc ccctcgcact     4260

gttgcttttc ctgatggtta atactactgt cacgtagctg tgtacaaaga gatgtgaaat     4320

actttcaggc aaaaataaac tgtaagtgac tcatcaaaa                            4359


<210>  1601
<211>  4133
<212>  DNA
<213>  homo sapiens

<400>  1601
ggcttcttgg atgggctggg cgtgcatggc ataaccgttt gagaacaaca aaccaagccg       60

gccgggctgc cgctctgttt cctgcgagga gggaagttac agatctccgc cctggcgtcc      120

ggggaaggat gggacaggct gctgagccaa ctgggtacat ggaaaactca gtctcctaca      180

gcgcaattga agacgttcag ctgctgtcct gggagaatgc cccgaagtac tgtttacagc      240

tcacgattcc tgggggaact gtcttactgc aggctgccaa tagctacctg cgagaccagt      300

ggttccattc tctgcaatgg aagaaaaaga tttacaaata taagaaagtg ctgagtaacc      360

caagccgctg ggaagttgtc ttgaaagaga tccggaccct ggtggacatg gccctgacat      420

cccccctgca ggatgactcc atcaaccagg ccccactgga aatcgtctcg aaactgctct      480

cagagaacac aaacttgacc acccaggagc atgaaaacat cattgtggca atcgctcctt      540

tgctggaaaa caaccaccca ccaccagatc tctgtgaatt cttttgcaag cactgcagag      600

agcggccccg gtccatggtg gtcatcgagg tgttcacccc cgtggtgcag cgaatcctca      660

agcataacat ggactttggg aagtgcccgc gactgaggct gtttactcag gagtacatcc      720

ttgccttgaa cgagctcaac gcggggatgg aagtggtgaa gaagttcatt cagagcatgc      780

acggccccac agggcactgc ccccaccccc gggtcctgcc caacctggtg gccgtgtgcc      840

tggctgccat ctactcctgc tatgaagagt tcatcaacag ccgcgacaat tccccaagcc      900

tgaaggaaat ccggaacggc tgccagcagc cgtgcgaccg gaagcccact ttacctctgc      960

gccttctgca ccccagcccg gacctggtgt ctcaggaagc cacgctgtct gaggcccggc     1020

tcaagtcggt ggtcgtggcc tccagtgaga tccacgtgga ggtggaacgc accagcactg     1080

ccaagccggc gctgacggcc agcgcaggca acgacagcga gcccaacctc atcgactgcc     1140

tcatggtcag ccccgcctgc agcaccatga gcatcgagct gggcccccag gccgaccgca     1200

cgctcggctg ctacgtggaa atcctcaagc tgctgtcaga ctatgatgac tggagaccgt     1260

ctctggccag tttgcttcaa cccattccat tccccaaaga agctctcgca catgagaagt     1320

tcaccaagga actgaagtac gtgattcaga ggttcgccga agaccccagg caagaggtcc     1380

actcatgcct gctgagcgtg cgggccggca aagatggctg gttccagctc tacagccccg     1440

gaggggtggc ctgcgacgat gacggggagc tgttcgccag catggtgcac atcctcatgg     1500

gctcctgtta caagaccaaa aaattcctgc tctccctggc agaaaacaag ctgggtccct     1560

gcatgctcct ggcactgagg gggaaccaga ccatggtgga gatcctgtgc ttgatgctgg     1620

aatacaacat catcgacaac aacgacaccc aactgcagat catctcaacc ctggagagca     1680

cagacgtggg gaagcgcatg tacgagcagc tgtgtgaccg gcagcgggag ctgaaggagc     1740

tgcaaaggaa aggcgggccc accaggctaa cactgccctc caagtccaca gacgctgact     1800

tggctcgttt gctgagctcc ggctccttcg gaaacctgga gaacctcagt ttggccttca     1860

ccaatgtaac cagtgcctgc gccgagcacc tcatcaaact gccttcgctc aagcagctga     1920

acctgtggtc cactcagttt ggagacgctg gccttcggct cctgtcggaa cacctcacca     1980

tgctccaggt gctgaacctg tgcgagaccc cggtcacaga cgctggcctg ctggccctga     2040

gctccatgaa gagtctctgc agtttaaaca tgaacagcac caagctctca gctgacacct     2100

acgaagatct gaaggccaag cttcccaatt tgaaggaagt ggacgtccgc tacaccgaag     2160

cctggtgaag ctcccagctc aaggcaggaa gacgtttgca accgcgacaa aataactctt     2220

gactaacagc cgcagagcag ccggtcctgg ggtcccaccc tggtgccctg gctgtgagat     2280

agatggggag tctttctggg ggcggagggg ggagggggtg gggagggggc ccacaagcac     2340

gcccagcccc cgccgaattc ttttagcttc gtaattggaa cctttgacct gatctaaagt     2400

ggactttgta gcaacaagag gagcatcagc gggtcgggga ggggtttggg ggtgggctgg     2460

ggggtggggg accctttgtg gattttcttt gcctttgtgt ttgatgccgt cgtgtgggaa     2520

aagtcaactc cgatgccacc attgcgggcc ggacgaagga tgctttcttc ctagaggctc     2580

cgagctgagc tgcgaactcg ccccccgccc ttgggacaag aagacccagt cacatcactg     2640

cacccgtcct gtgtcctcac cattgctatg caaagtgatt cttgttgtac ataagattta     2700

aataatgcac ctatttaaga catgttgaca aattgcgggt ctgggacccg cctcttattt     2760

atgaagtctt tgaccgtccc ccccgcccga ccccaccgcc ctcccgcccc cacctggcgt     2820

gtagtactgt ataaaccagt cagctgtcgg gttagtggta gtattattgt tattttttta     2880

aaggaaacaa acagacaaca aaaagaagaa aaaaaaaaag aacctccttg gaaaaattaa     2940

ttgctttttc gtaatggatt ctctatgcta atgctctctc gtctgtctgt ctgtctgccc     3000

actcccccac ccaccactgt gcgtttctga tttccaaatg tctccaactc cctcacgagg     3060

tggggctcag gctggaggag gagggattaa gatccccttg ctccactaag gcccaagctc     3120

tttctctcgg caccttttag acttgaatgg gaggctgcta acccgccctc tccagtccac     3180

cccggtaaaa gagctgttcc ccacccccag ggagctcctg tccctgtcag cctttgctgt     3240

cccctgtccc caacggagac tctgtcaccc ctgggctccc cctgccatcg tgtgcttcac     3300

gtggccccat gcatgcccgc ctctctgcat ggtctcttgg gaaaagagag atgtgtcgcc     3360

tccgccagtc cgactgccct ccccacccca cccccgccac cccccacatg tgaccactgc     3420

aacgaagaca ctccttctgt ccccacctgc tccgaagaca aaccaacctc cgtttctttt     3480

ataaacagtc ggctttttct taataagccc tcactgtaca gaacagcccg ttgatggttt     3540

atttggggtc cccctctccc cccagccctt ttttctgttg gtttagcaca aatacttccc     3600

tcctccggca cctccaaacc taccccacag tcagtgtact tgttttatat atatttaatc     3660

ttattcaatg gaaaccatgc ttttgtcgtt ttatactttg ctaggtagac tttattaccc     3720

ccccactatg ccctcatttt tttaaaaaag gaaaaaaaaa agaaactggg ttccagtctt     3780

aattcatttt ccgtgccagg ttttatttcg tgtgtgtgtg agtgtgttct gttttgtgtt     3840

ttgttttttg ttgttgtttt tagttgtttg gttttctttt ctttcccccc tccggtccca     3900

tacttcacag cactctggtg cgggaagaag cagaagcaaa aaaaataaaa ataaaaaaat     3960

aaataaaaat aaaaaaaata aaaaaggaaa aaaaaaaaag aagaaacaag acatgccacc     4020

tttcccctcg cactgttgct tttcctgatg gttaatacta ctgtcacgta gctgtgtaca     4080

aagagatgtg aaatactttc aggcaaaaat aaactgtaag tgactcatca aaa            4133


<210>  1602
<211>  3339
<212>  DNA
<213>  homo sapiens

<400>  1602
attgcgctcc gctggctggt gattggttgg gatgcaccgt ctatcacctg cttccttgtg       60

agaatctagg tctctaaggg aagcgttact tgaggctcgg ttgggaagag atgggcagct      120

ctcaaaaaag gcacaaacaa ttgaaggatg gataccatgg catatgttaa aagcgtgttg      180

aaaggaaaat aagaaagcca ggaatctcag gatgaatcag tctagatcga gatcagatgg      240

tggcagtgaa gaaaccttac ctcaagacca taatcatcat gaaaatgaga gaagatggca      300

gcaagagcgt ctccacagag aagaggccta ttatcagttt attaatgaac tcaatgatga      360

agattatcgg cttatgagag accataatct tttaggcacc cctggagaaa taacatcaga      420

agaactgcaa cagcggttag atggcgtcaa ggaacaacta gcatctcagc ctgacttgag      480

agatggaacg aattacagag actcagaagt ccctagagaa agttcacatg aagattctct      540

tctagaatgg ttgaacacct ttcggcgcac aggaaatgca actcgaagtg gacaaaatgg      600

gaaccaaact tggagagctg tgagtcgaac aaacccgaac aatggagagt ttcggtttag      660

tttggaaatc cacgtaaatc atgaaaatag aggatttgaa attcatggag aagattatac      720

agacattcca ctttcagata gtaacagaga tcatactgca aataggcaac aaaggtcaac      780

tagtcctgtg gctaggcgaa caagaagcca aacctcagtg aatttcaatg gtagtagttc      840

caacattcca aggactaggc ttgcttcaag ggggcaaaat ccagctgaag gatctttctc      900

aacattggga aggttaagaa atggaattgg gggagcagct ggcattcctc gagctaacgc      960

ttcacgcact aatttcagta gtcacacaaa ccaatcaggt ggtagtgaac tcaggcaaag     1020

ggaggggcaa cggtttggag cagcacatgt ttgggaaaat ggggctagaa gtaatgttac     1080

agtgaggaat acaaaccaaa gattagagcc aataagatta cgatctactt ccaatagtcg     1140

aagccgttca ccaattcaga gacagagtgg cactgtttat cataattccc aaagggaaag     1200

tagaccagta cagcaaacca ctagaagatc tgttaggagg agaggtagaa ctcgagtctt     1260

tttagagcaa gatagagaac gagaacgcag aggtactgca tataccccat tctctaattc     1320

aaggcttgtg tcaagaataa cagtagaaga aggagaagaa tccagcagat cctcaactgc     1380

tgtacgacga catccaacaa tcacactgga ccttcaagtg agaaggatcc gtcctggaga     1440

aaatagagat cgggatagta ttgcaaatag aactcgatcc agagtagggc tagcagaaaa     1500

tacagtcact attgaaagca atagtggggg ctttcgccga accatttctc gtttagagcg     1560

gtcaggtatt cgaacctatg ttagtaccat aacagttcct cttcgtagga tttctgagaa     1620

tgagcttgtt gagccatcat cagtggctct tcggtcaatt ttaaggcaga tcatgactgg     1680

gtttggagaa ctgagttctc taatggaggc cgattctgag tcagaacttc aaagaaatgg     1740

ccagcattta ccagacatgc actcagaact gagtaactta ggtacagata acaacaggag     1800

ccagcacagg gaaggttcct ctcaagacag gcaggcccaa ggagacagca ctgaaatgca     1860

tggtgaaaac gagaccaccc agcctcatac tcgaaacagt gacagtaggg gtggcaggca     1920

gttgcgaaat ccaaacaatt tagttgaaac tggaacacta cccattcttc gccttgctca     1980

ctttttttta ctaaatgaaa gtgatgatga tgatcgaata cgtggtttaa ccaaagagca     2040

gattgacaat ctttccacca ggcactatga gcataacagt attgatagtg aactaggtaa     2100

aatctgtagt gtttgtatta gtgactatgt aactggaaac aagctcaggc aattaccttg     2160

catgcatgaa tttcacattc attgtattga ccgatggctc tcagagaatt gcacttgtcc     2220

gatctgtcgg cagcctgttt tagggtctaa catagcaaac aatgggtaag gtgatgggat     2280

ctactcaaat actgtttttt agtagaactg aatgttcaag cattgttttg ctgagttatt     2340

tgtgattagc taaccaggat gaaaaataac agattatata tagtttgaac tatttttcgt     2400

gtgctttttt aaacttgtta aaaagaaatt tatataaaat ttaaaataca aatgttaaat     2460

tatccagaaa tacagaatag ttaatattgc tagaaccaaa taacctctaa aatgttttta     2520

ttttggtaat tttgtcatgc taagcacttt tgtatctgca caattcagta ggttaagaat     2580

caatcttctt tttcttaata gtacagcaga ctttagcttc aagtttcata ggcttagtac     2640

ttatatctag acatttgtgt ctaaataagc ttttcattaa ctttttattt taaggacagt     2700

atcttttcat gaaagagtat ttggctgaat gtttgctata tatatgttac ttgaaatgtt     2760

aaatttaata tgcagcatac cataggtgta tatataggta tataatttta aggttaaaat     2820

attcagtcta caagtttggt tcttatttaa gcttttgggc taatactgca tatggcacaa     2880

tgtttaatat tggcaagttc atctcagaga aaggggattc agatataatt ttaaagtaga     2940

gataatttac tgaagcgtct ctgacaatct aacttattag acagcaagca atatataata     3000

ctgaaaaagt attcagaaat ggaaaattta catcatatag gttatttaac ttgtgttcag     3060

cctttttgta acttttttga aagtgcaaac aattctttgg attattaaat aaggtataca     3120

gtatgcatgg tttctcaaat ttagttttaa aatctaaaag tctataaaga atcagatgca     3180

taggcaatat gttaagttca cttggaggct aaaaatctcc agtgaaaaca aaacgaaaac     3240

ctttaagaga atgtagagtt tatataaaca caaagtatgc attgaagatc tgtttctacc     3300

aataaacatt aaaacaaaga ctgtaaaaaa aaaaaaaaa                            3339


<210>  1603
<211>  3473
<212>  DNA
<213>  homo sapiens

<400>  1603
tttatttatc gtagtgggga tcgtcccccg gcgcgagctt ccgtcgcaac ggccgggaaa       60

gaaaccagta gcgggacgga gggcgggggt ggcaagaaag tcaaggttta gaagtaagcc      120

ggagacgcct aaccctggta acatccgaat gggaacggga taggaaggaa ggcctttgag      180

agaggaggcg taaacccagg aacagtgaca gtgtaggacg aaaggcctaa gtttgttgcg      240

gaagatgggc agctctcaaa aaaggcacaa acaattgaag gatggatacc atggcatatg      300

ttaaaagcgt gttgaaagga aaataagaaa gccaggaatc tcaggatgaa tcagtctaga      360

tcgagatcag atggtggcag tgaagaaacc ttacctcaag accataatca tcatgaaaat      420

gagagaagat ggcagcaaga gcgtctccac agagaagagg cctattatca gtttattaat      480

gaactcaatg atgaagatta tcggcttatg agagaccata atcttttagg cacccctgga      540

gaaataacat cagaagaact gcaacagcgg ttagatggcg tcaaggaaca actagcatct      600

cagcctgact tgagagatgg aacgaattac agagactcag aagtccctag agaaagttca      660

catgaagatt ctcttctaga atggttgaac acctttcggc gcacaggaaa tgcaactcga      720

agtggacaaa atgggaacca aacttggaga gctgtgagtc gaacaaaccc gaacaatgga      780

gagtttcggt ttagtttgga aatccacgta aatcatgaaa atagaggatt tgaaattcat      840

ggagaagatt atacagacat tccactttca gatagtaaca gagatcatac tgcaaatagg      900

caacaaaggt caactagtcc tgtggctagg cgaacaagaa gccaaacctc agtgaatttc      960

aatggtagta gttccaacat tccaaggact aggcttgctt caagggggca aaatccagct     1020

gaaggatctt tctcaacatt gggaaggtta agaaatggaa ttgggggagc agctggcatt     1080

cctcgagcta acgcttcacg cactaatttc agtagtcaca caaaccaatc aggtggtagt     1140

gaactcaggc aaagggaggg gcaacggttt ggagcagcac atgtttggga aaatggggct     1200

agaagtaatg ttacagtgag gaatacaaac caaagattag agccaataag attacgatct     1260

acttccaata gtcgaagccg ttcaccaatt cagagacaga gtggcactgt ttatcataat     1320

tcccaaaggg aaagtagacc agtacagcaa accactagaa gatctgttag gaggagaggt     1380

agaactcgag tctttttaga gcaagataga gaacgagaac gcagaggtac tgcatatacc     1440

ccattctcta attcaaggct tgtgtcaaga ataacagtag aagaaggaga agaatccagc     1500

agatcctcaa ctgctgtacg acgacatcca acaatcacac tggaccttca agtgagaagg     1560

atccgtcctg gagaaaatag agatcgggat agtattgcaa atagaactcg atccagagta     1620

gggctagcag aaaatacagt cactattgaa agcaatagtg ggggctttcg ccgaaccatt     1680

tctcgtttag agcggtcagg tattcgaacc tatgttagta ccataacagt tcctcttcgt     1740

aggatttctg agaatgagct tgttgagcca tcatcagtgg ctcttcggtc aattttaagg     1800

cagatcatga ctgggtttgg agaactgagt tctctaatgg aggccgattc tgagtcagaa     1860

cttcaaagaa atggccagca tttaccagac atgcactcag aactgagtaa cttaggtaca     1920

gataacaaca ggagccagca cagggaaggt tcctctcaag acaggcaggc ccaaggagac     1980

agcactgaaa tgcatggtga aaacgagacc acccagcctc atactcgaaa cagtgacagt     2040

aggggtggca ggcagttgcg aaatccaaac aatttagttg aaactggaac actacccatt     2100

cttcgccttg ctcacttttt tttactaaat gaaagtgatg atgatgatcg aatacgtggt     2160

ttaaccaaag agcagattga caatctttcc accaggcact atgagcataa cagtattgat     2220

agtgaactag gtaaaatctg tagtgtttgt attagtgact atgtaactgg aaacaagctc     2280

aggcaattac cttgcatgca tgaatttcac attcattgta ttgaccgatg gctctcagag     2340

aattgcactt gtccgatctg tcggcagcct gttttagggt ctaacatagc aaacaatggg     2400

taaggtgatg ggatctactc aaatactgtt ttttagtaga actgaatgtt caagcattgt     2460

tttgctgagt tatttgtgat tagctaacca ggatgaaaaa taacagatta tatatagttt     2520

gaactatttt tcgtgtgctt ttttaaactt gttaaaaaga aatttatata aaatttaaaa     2580

tacaaatgtt aaattatcca gaaatacaga atagttaata ttgctagaac caaataacct     2640

ctaaaatgtt tttattttgg taattttgtc atgctaagca cttttgtatc tgcacaattc     2700

agtaggttaa gaatcaatct tctttttctt aatagtacag cagactttag cttcaagttt     2760

cataggctta gtacttatat ctagacattt gtgtctaaat aagcttttca ttaacttttt     2820

attttaagga cagtatcttt tcatgaaaga gtatttggct gaatgtttgc tatatatatg     2880

ttacttgaaa tgttaaattt aatatgcagc ataccatagg tgtatatata ggtatataat     2940

tttaaggtta aaatattcag tctacaagtt tggttcttat ttaagctttt gggctaatac     3000

tgcatatggc acaatgttta atattggcaa gttcatctca gagaaagggg attcagatat     3060

aattttaaag tagagataat ttactgaagc gtctctgaca atctaactta ttagacagca     3120

agcaatatat aatactgaaa aagtattcag aaatggaaaa tttacatcat ataggttatt     3180

taacttgtgt tcagcctttt tgtaactttt ttgaaagtgc aaacaattct ttggattatt     3240

aaataaggta tacagtatgc atggtttctc aaatttagtt ttaaaatcta aaagtctata     3300

aagaatcaga tgcataggca atatgttaag ttcacttgga ggctaaaaat ctccagtgaa     3360

aacaaaacga aaacctttaa gagaatgtag agtttatata aacacaaagt atgcattgaa     3420

gatctgtttc taccaataaa cattaaaaca aagactgtaa aaaaaaaaaa aaa            3473


<210>  1604
<211>  7103
<212>  DNA
<213>  homo sapiens

<400>  1604
cactcgctct ctccctctgt gtatagagga tgtgctgaat ggtgcgcttt gaggcggcgg       60

cggcggagga gcagaatccg ccgcgactgg cagcctcggc tgaccggctc ggcttctctt      120

cgccttccga ggctcctcat ccaccgcggg ctccagacct cgcgtcccgc ccggggcatg      180

gccgggcgct gcgcccccgc gcgctctgcc tgctgagcgg cgccggaggg aggtgcggag      240

gccgggaggc cggggaggcc ggcggggagc agagtcgagc gcctccggag cagagaaagg      300

agcccgcgcc ccgcgccccg cgccccgcgc acggtcccca gtccctgccg cgctcgcccg      360

ggccgcccgg agcccagatg agcccagatg gccggggctc aacccggagt gcacgccttg      420

caactcaagc ccgtgtgcgt gtccgacagc ctcaagaagg gcaccaaatt cgtcaagtgg      480

gatgatgact caactattgt tactccaatt attttgagga ctgaccctca gggatttttc      540

ttttactgga cagatcaaaa caaggagaca gagctactgg atctcagcct tgtcaaagat      600

gccagatgtg ggagacacgc caaagctccc aaggacccca aattacgtga acttttggat      660

gtggggaaca tcgggcgcct ggagcagcgc atgatcacag tggtgtatgg gcctgacctc      720

gtgaacatct cccatttgaa tctcgtggct ttccaagaag aagtggccaa ggaatggaca      780

aatgaggttt tcagtttggc aacaaacctg ctggcccaaa acatgtccag ggatgcattt      840

ctggaaaaag cctatactaa acttaagctg caagtcactc cagaagggcg tattcctctc      900

aaaaacatat atcgcttgtt ttcagcagat cggaagcgag ttgaaactgc tttagaggct      960

tgtagtcttc catcttcaag gaatgattca atacctcaag aagatttcac tccagaagtg     1020

tacagagttt tcctcaacaa cctttgccct cgacctgaaa ttgataacat cttttcagaa     1080

tttggtgcaa aaagcaaacc atatcttacc gttgatcaga tgatggattt tatcaacctt     1140

aagcagcgag atcctcggct taatgaaata ctttatccac ctctaaaaca agagcaagtc     1200

caagtattga ttgagaagta tgaacccaac aacagcctcg ccagaaaagg acaaatatca     1260

gtggatgggt tcatgcgcta tctgagtgga gaagaaaacg gagtcgtttc acctgagaaa     1320

ctggatttga atgaagacat gtctcagccc ctttctcact atttcattaa ttcctcgcac     1380

aacacctacc tcacagctgg ccaactggct ggaaactcct ctgttgagat gtatcgccaa     1440

gtgctcctgt ctggttgtcg ctgtgtggag ctggactgct ggaagggacg gactgcagaa     1500

gaggaacctg tcatcaccca tggcttcacc atgacaactg aaatatcttt caaggaagtg     1560

atagaagcaa ttgcggagtg tgcatttaag acttcacctt ttccaattct cctttcgttt     1620

gagaaccatg tggattcccc aaagcagcaa gccaagatgg cggagtactg ccgactgatc     1680

tttggggatg cccttctcat ggagcccctg gaaaaatatc cactggaatc tggagttcct     1740

cttccaagcc ctatggattt aatgtataaa attttggtga aaaataagaa gaaatcacac     1800

aagtcatcag aaggaagcgg caaaaagaag ctctcagaac aagcctccaa cacctacagt     1860

gactcctcca gcatgttcga gccctcatcc ccaggagccg gagaagctga tacggaaagt     1920

gacgacgacg atgatgatga tgactgtaaa aaatcttcaa tggatgaggg gactgctgga     1980

agtgaggcta tggccacaga agaaatgtct aatctggtga actatattca gccagtcaag     2040

tttgagtcat ttgaaatttc aaaaaaaaga aataaaagtt ttgaaatgtc ttccttcgtg     2100

gaaaccaaag gacttgaaca actcaccaag tctccagtgg aatttgtaga atataacaaa     2160

atgcagctta gcaggatata tccaaaagga acacgtgtgg attcatccaa ctatatgcct     2220

cagctcttct ggaatgcagg ttgtcagatg gtggcactta atttccagac aatggacctg     2280

gctatgcaaa taaatatggg gatgtatgaa tacaacggga agagtggcta cagattgaag     2340

ccagagttca tgaggaggcc tgacaagcat tttgatccat ttactgaagg catcgtagat     2400

gggatagtgg caaacacttt gtctgttaag attatttcag gtcagtttct ttctgataag     2460

aaagttggga cttacgtgga agtagatatg tttggtttgc ctgtggatac aaggaggaag     2520

gcatttaaga ccaaaacatc ccaaggaaat gctgtgaatc ctgtctggga agaagaacct     2580

attgtgttca aaaaggtggt tcttcctact ctggcctgtt tgagaatagc agtttatgaa     2640

gaaggaggta aattcattgg ccaccgtatc ttgccagtgc aagccattcg gccaggctat     2700

cactatatct gtctaaggaa tgaaaggaac cagcctctga cgctgcctgc tgtctttgtc     2760

tacatagaag tgaaagacta tgtgccagac acatatgcag atgtcatcga agctttatca     2820

aacccaatcc gatatgtgaa cctgatggaa cagagagcta agcaattggc tgctttgaca     2880

ctggaagatg aagaagaagt aaagaaagag gctgatcctg gagaaacacc atcagaggct     2940

ccaagtgaag cgagaacgac tccagcagaa aatggggtga atcacactac aaccctgaca     3000

cccaagccac cctcccaggc tctccacagc cagccagctc caggttctgt aaaggcacct     3060

gccaaaacag aagatcttat tcagagtgtc ttaacagaag tggaagcaca gaccatcgaa     3120

gaactaaagc aacagaaatc gtttgtgaaa cttcaaaaga aacactacaa agaaatgaaa     3180

gacctggtta agagacacca caagaaaacc actgacctta tcaaagaaca cactaccaag     3240

tataatgaaa ttcagaatga ctacttgaga aggagagccg ctttggaaaa gtccgccaaa     3300

aaggacagta agaaaaaatc ggaacccagc agccctgatc atggttcatc aacgattgag     3360

caagacctcg ctgctctgga tgctgaaatg acccaaaagt taatagactt gaaggacaaa     3420

caacagcagc agctgcttaa tcttcggcaa gaacagtatt atagtgaaaa ataccagaag     3480

cgagaacata ttaaactgct tattcaaaag ttgacggatg tcgcagaaga gtgtcagaac     3540

aatcagttaa agaagctcaa agaaatctgt gagaaagaaa agaaagaatt aaagaagaaa     3600

atggataaaa agaggcagga gaagataaca gaagctaaat ccaaagacaa aagtcagatg     3660

gaagaggaga agacagagat gatccggtca tatatccagg aagtggtgca gtatatcaag     3720

aggctagaag aagcgcaaag taaacggcaa gaaaaactcg tagagaaaca caaggaaata     3780

cgtcagcaga tcctggatga aaagcccaag ctgcaggtgg agctggagca agaataccaa     3840

gacaaattca aaagactgcc cctcgagatt ttggaattcg tgcaggaagc catgaaagga     3900

aagatcagtg aagacagcaa tcacggttct gcccctctct ccctgtcctc agaccctgga     3960

aaagtgaacc acaagactcc ctccagtgag gagctgggag gagacatccc aggaaaagaa     4020

tttgatactc ctctgtgaat gctcctgcca ggccttcaga aattgcatgg ccactccagc     4080

gtcatcggac tctctcttat tacaaagatc actgcccagg accatcttcc cgagaagcat     4140

cccttagcct aaaatccaca ccaaagggag agttccagag gaatccatga agaattccca     4200

tgcccaggct ccatgtgtca tgtggaaacc tccacaggtc tgctagtgaa gaatgcatgt     4260

atgtgagatt tttgttttct ttccaatagc aaattcaaag caagcaactt gcaggctcca     4320

tggaactttt aatgaaggac agtgtcttct ttgaagaaaa tcaagctcgt gtttttattc     4380

gaagctctgg tgtaaaatat ttcaaagtca tagaaatagt ttgagaaatg catagcatta     4440

tttaacacta ttgaacagcc gactttgagc attgtttctt ctaactgccc ctcaactacc     4500

attatcttca agtcaacatg catattacat tttcatcctt tgctttgcaa gcactggtgg     4560

cttgcagttt gctaatttat ttatcataga gtcatcaatg tatttgttgc tgacatggtt     4620

ttattagata ctgtagtgat tcaaataagt tttctatttg aaaaaaaaaa tcacttgatt     4680

gtatccttgc ccagtgaagc catcctaaga cttagcaata tggattgtac atttggctgc     4740

atgagcaagt cggccgcaca cttccagaca gtgtgctgtt tgaattgact atttgcactc     4800

aaagtctggg tattcattgg ttattggcct gaaatgatca aataactaca aatgatctgt     4860

tgaataaaaa tagttgagct gatatatgtt aagcagatat tcaatcagaa tgaacaggtt     4920

ccggtggtta ttttgccgtt tgacattttt tatggttcat ttatttttaa tatagagagg     4980

aagattgaat atttatctag agaatacaaa gacccacatg taaatgatag gtattatctc     5040

catgtatata tgtacccact tagtcatgta agtgcatata cacatacaca cacatgagtg     5100

tagacatgtg tttattaatt gacaatgacc caaatctctt ccacaagact taaaaccaaa     5160

ttcagggaca aatggataga gaagaaaagg gtcaaacatc gagattacat ggatgttaaa     5220

ttatatggag acgctaagaa ataattgatg gagccattga tgcaaaccga agtagattta     5280

gaacttatat gaatttgatt tatattttgc aagatcaaaa attagatgtt aagtatcaga     5340

ttttaagctt gttttaatgg tcaaaaaatt aggacagaaa taatatggac atttattagt     5400

atcttccata atttttaagt ctgacacatt tctattttat tctaacataa aaaaacttcc     5460

attatatatt tactaagtat atttaattca cttaactctg tctttataag ttcctatttt     5520

agatggaata agagaaacaa attatatcaa ggtaaaactg atcaaaagca taattgaaag     5580

ttctgaaaaa agaaaaataa taatatgtag aaaaatgtaa cttagagagt aacacatgaa     5640

cattgaagtt aaaacccaga agccagatgc tcacagtttt attttacttt aaaataaacc     5700

tgtctgactg tagctttgtg aaatatctta aaacgcaaaa accaattgtg tcctgaaaat     5760

tgtttcaaga atttaatatt tttatgaaaa ttattttatt taactttaag caataactag     5820

agattacaat taaattttaa tcaaaatgaa ggcttagttc aaacataagg aaacagtgtt     5880

tgattaaaaa aaacacatct agtaagacgt aaggggaaaa tcacatcctc tttggagatg     5940

attatatttt gatctgaagg gtttggggtg ttcattagac acttaataaa acttaacttc     6000

caatgaaaaa gaaatctttt gtaaatcatt ctacttttgc actttgaaag aaaggcgtta     6060

atcataaaga agcaagaatg gtcaaaatcg aatgctgcat ttttataaac aaaattacag     6120

actgtctgaa attgaagaag aatgaactaa taatagcatt cataaccaaa cacaatgatg     6180

attattgcag aacattgtat cacattttag tccagagata gaataaagtt gaataacctt     6240

gacttacaca aaactgtttt ggtagttgga tttcattatc ttagtgaatt tagtcatttt     6300

acaatatgtt tgtatttggc catttactgt aatcacattt ttatatctgt acaatgacac     6360

tttttgcagt tgtggggtag tgtgtaacac tgtccatctt gcatcattga aactactaca     6420

atgatactat catttaataa tattaatatt acttgaaata gactaagata aagaaaaggg     6480

gtctgtatga tgtgcagttt tgtgccttta tgtatttgcc ttgttctttg tcgaatgtgt     6540

gaaattccgt actgtggttt ttcctataat agaaagtaga gctgtgtatt aaattagact     6600

gtgtctctct gataccttta cactactgag aatagcatgg ttttggccat gtaaaccaat     6660

tttcaaagtt ctaatgacat agccatgtgt ttttggtttt ttatatttca ttttaaaatt     6720

tgagtatcac catacattaa ttaatactcc tgtagtagat aagctgtcat taagtaattc     6780

ccaaaaaaag ggccatttgc ttgcattact ttgaatttaa tgttgcgctt gtgcactgtg     6840

ttaatattgt ttgtgatgga ttggacgttg tgactcttgc cttttaagaa gaaaaaaaag     6900

ataggacaaa gtatttgaag ctcttaaaat gtacatattt tggttcttct atctcaaatt     6960

atttaaaatg cataattcac atttttgtaa taattctatg caattttgtg gcatgatgtt     7020

tcttccactt gtaattttat gtgctttcat cacaaatcca aaggaaagaa taaaaatttc     7080

ttaacacaaa aaaaaaaaaa aaa                                             7103


<210>  1605
<211>  1878
<212>  DNA
<213>  homo sapiens

<400>  1605
gattgtggga aggcagctga actcggcgcc tggaaagatg gaggcagcgg agacagaggc       60

ggaagctgca gccctagagg tcctggctga ggtggcaggc atcttggaac ctgtaggcct      120

gcaggaggag gcagaactgc cagccaagat cctggttgag tttgtggtgg actctcagaa      180

gaaagacaag ctgctctgca gccagcttca ggtagcggat ttcctgcaga acatcctggc      240

tcaggaggac actgctaagg gtctcgaccc cttggcttct gaagacacga gccgacagaa      300

ggcaattgca gctaaggaac aatggaaaga gctgaaggcc acctacaggg agcacgtaga      360

ggccatcaaa attggcctca ccaaggccct gactcagatg gaggaagccc agaggaaacg      420

gacacaactc cgggaagcct ttgagcagct ccaggccaag aaacaaatgg ccatggagaa      480

acgcagagca gtccagaacc agtggcagct acaacaggag aagcatctgc agcatctggc      540

ggaggtttct gcagaggtga gggagcgtaa gacagggact cagcaggagc ttgacagggt      600

gtttcagaaa cttggaaacc tgaagcagca ggcagaacag gagcgggaca agctgcagag      660

gtatcagacc ttcctccagc ttctgtatac cctgcagggt aagctgttgt tccctgaggc      720

tgaggctgag gcagagaatc ttccagatga taaaccccag cagccgactc gaccccagga      780

gcagagtaca ggagacacca tggggagaga ccctggtgtg tccttcaagg ctgttggtct      840

acaacctgct ggagatgtaa atttgccatg acttcctgga ggacagcagc atggagaaag      900

atcctagaaa aggtcagacc caactcaggc cttggtgtcc ctggactgca agtgtggaag      960

gagggaaagc ctggtttacc tctctctgca tctgagctct gctacccatg gagcagatgg     1020

atggtgggaa caggaaagag cttatgttac acctcattcc catgcttagc ccacccagag     1080

ctaacccctg tcttcttccc caggcctctg acttccctca cctcccaacc atcattacag     1140

gaaagactgt gaactcctga gttcagcttg atttctgact acatcccagc aagctctggc     1200

atctgtggat taaaatccct ggatctctct cagttgtgta tttgttcatc ttcatatgct     1260

ggcaggaaca actattaata cagatactca gaagccaata acatgacagg agctgggact     1320

ggtttgaaca cagggtgtgc agatggggag ggggtactgg ccttgggcct cctatgatgc     1380

agacatggtg aatttaattc aaggaggagg agaatgtttt aggcaggtgg ttatatgtgg     1440

gaagataatt ttattcatgg atccaaatgt ttgttgagtc ctttctttgt gctaaggttc     1500

ttgcggtgaa ccagaattat aacagtgagc tcatctgact gttttaggat gtacagccta     1560

gtgttaacat tcttggtatc tttttgtgcc ttatctaaaa catttctcga tcactggttt     1620

cagatgttca tttattatat tcttttcaaa gattcagaga ttggcttttg tcatccacta     1680

ttgtatgttt tgtttcattg acctctagtg ataccttgat ctttcccact ttctgttttc     1740

ggattggaga agatgtacct tttttgtcaa ctcttacttt tatcagatga tcaactcacg     1800

tatttggatc tttatttgtt ttctcaaata aatatttaag gttatacatt taaaaaaaaa     1860

aaaaaaaaaa aaaaaaaa                                                   1878


<210>  1606
<211>  1774
<212>  DNA
<213>  homo sapiens

<400>  1606
aggaaagaaa gaaagcgagg gagggaaaga ggaggaagga agatgcgaga aggcagagga       60

ggagggaggg agggaaggag cgcggagccc ggcccggaag ctaggagcca ttccgtagtg      120

ccatcccgag caacgcactg ctgcagcttc cctgagcctt tccagcaagt ttgttcaaga      180

ttggctgtca agaatcatgg actgttatta tatgccttgt tttctgtcaa gacaccatga      240

ttcctggtaa ccgaatgctg atggtcgttt tattatgcca agtcctgcta ggaggcgcga      300

gccatgctag tttgatacct gagacgggga agaaaaaagt cgccgagatt cagggccacg      360

cgggaggacg ccgctcaggg cagagccatg agctcctgcg ggacttcgag gcgacacttc      420

tgcagatgtt tgggctgcgc cgccgcccgc agcctagcaa gagtgccgtc attccggact      480

acatgcggga tctttaccgg cttcagtctg gggaggagga ggaagagcag atccacagca      540

ctggtcttga gtatcctgag cgcccggcca gccgggccaa caccgtgagg agcttccacc      600

acgaagaaca tctggagaac atcccaggga ccagtgaaaa ctctgctttt cgtttcctct      660

ttaacctcag cagcatccct gagaacgagg tgatctcctc tgcagagctt cggctcttcc      720

gggagcaggt ggaccagggc cctgattggg aaaggggctt ccaccgtata aacatttatg      780

aggttatgaa gcccccagca gaagtggtgc ctgggcacct catcacacga ctactggaca      840

cgagactggt ccaccacaat gtgacacggt gggaaacttt tgatgtgagc cctgcggtcc      900

ttcgctggac ccgggagaag cagccaaact atgggctagc cattgaggtg actcacctcc      960

atcagactcg gacccaccag ggccagcatg tcaggattag ccgatcgtta cctcaaggga     1020

gtgggaattg ggcccagctc cggcccctcc tggtcacctt tggccatgat ggccggggcc     1080

atgccttgac ccgacgccgg agggccaagc gtagccctaa gcatcactca cagcgggcca     1140

ggaagaagaa taagaactgc cggcgccact cgctctatgt ggacttcagc gatgtgggct     1200

ggaatgactg gattgtggcc ccaccaggct accaggcctt ctactgccat ggggactgcc     1260

cctttccact ggctgaccac ctcaactcaa ccaaccatgc cattgtgcag accctggtca     1320

attctgtcaa ttccagtatc cccaaagcct gttgtgtgcc cactgaactg agtgccatct     1380

ccatgctgta cctggatgag tatgataagg tggtactgaa aaattatcag gagatggtag     1440

tagagggatg tgggtgccgc tgagatcagg cagtccttga ggatagacag atatacacac     1500

cacacacaca caccacatac accacacaca cacgttccca tccactcacc cacacactac     1560

acagactgct tccttatagc tggactttta tttaaaaaaa aaaaaaaaaa aggaaaaaat     1620

ccctaaacat tcaccttgac cttatttatg actttacgtg caaatgtttt gaccatattg     1680

atcatatatt ttgacaaaat atatttataa ctacgtatta aaagaaaaaa ataaaatgag     1740

tcattatttt aaaggtaaaa aaaaaaaaaa aaaa                                 1774


<210>  1607
<211>  1774
<212>  DNA
<213>  homo sapiens

<400>  1607
aggaaagaaa gaaagcgagg gagggaaaga ggaggaagga agatgcgaga aggcagagga       60

ggagggaggg agggaaggag cgcggagccc ggcccggaag ctaggagcca ttccgtagtg      120

ccatcccgag caacgcactg ctgcagcttc cctgagcctt tccagcaagt ttgttcaaga      180

ttggctgtca agaatcatgg actgttatta tatgccttgt tttctgtcaa gacaccatga      240

ttcctggtaa ccgaatgctg atggtcgttt tattatgcca agtcctgcta ggaggcgcga      300

gccatgctag tttgatacct gagacgggga agaaaaaagt cgccgagatt cagggccacg      360

cgggaggacg ccgctcaggg cagagccatg agctcctgcg ggacttcgag gcgacacttc      420

tgcagatgtt tgggctgcgc cgccgcccgc agcctagcaa gagtgccgtc attccggact      480

acatgcggga tctttaccgg cttcagtctg gggaggagga ggaagagcag atccacagca      540

ctggtcttga gtatcctgag cgcccggcca gccgggccaa caccgtgagg agcttccacc      600

acgaagaaca tctggagaac atcccaggga ccagtgaaaa ctctgctttt cgtttcctct      660

ttaacctcag cagcatccct gagaacgagg tgatctcctc tgcagagctt cggctcttcc      720

gggagcaggt ggaccagggc cctgattggg aaaggggctt ccaccgtata aacatttatg      780

aggttatgaa gcccccagca gaagtggtgc ctgggcacct catcacacga ctactggaca      840

cgagactggt ccaccacaat gtgacacggt gggaaacttt tgatgtgagc cctgcggtcc      900

ttcgctggac ccgggagaag cagccaaact atgggctagc cattgaggtg actcacctcc      960

atcagactcg gacccaccag ggccagcatg tcaggattag ccgatcgtta cctcaaggga     1020

gtgggaattg ggcccagctc cggcccctcc tggtcacctt tggccatgat ggccggggcc     1080

atgccttgac ccgacgccgg agggccaagc gtagccctaa gcatcactca cagcgggcca     1140

ggaagaagaa taagaactgc cggcgccact cgctctatgt ggacttcagc gatgtgggct     1200

ggaatgactg gattgtggcc ccaccaggct accaggcctt ctactgccat ggggactgcc     1260

cctttccact ggctgaccac ctcaactcaa ccaaccatgc cattgtgcag accctggtca     1320

attctgtcaa ttccagtatc cccaaagcct gttgtgtgcc cactgaactg agtgccatct     1380

ccatgctgta cctggatgag tatgataagg tggtactgaa aaattatcag gagatggtag     1440

tagagggatg tgggtgccgc tgagatcagg cagtccttga ggatagacag atatacacac     1500

cacacacaca caccacatac accacacaca cacgttccca tccactcacc cacacactac     1560

acagactgct tccttatagc tggactttta tttaaaaaaa aaaaaaaaaa aggaaaaaat     1620

ccctaaacat tcaccttgac cttatttatg actttacgtg caaatgtttt gaccatattg     1680

atcatatatt ttgacaaaat atatttataa ctacgtatta aaagaaaaaa ataaaatgag     1740

tcattatttt aaaggtaaaa aaaaaaaaaa aaaa                                 1774


<210>  1608
<211>  2859
<212>  DNA
<213>  homo sapiens

<400>  1608
aaactttcgt gcgcgttgaa agctgctggc gcggcggggc ggactccacc cctgcccggc       60

agcccagcgc ctccggccgc acttccagct ctctgcgcag cccgccgcgc agcccgccgc      120

cccagccatg gcgaagcccc tgacggacca ggagaagcgg cggcagatca gcatccgcgg      180

catcgtgggc gtggagaacg tggcagagct gaagaagagt ttcaaccggc acctgcactt      240

cacgctggtc aaggaccgca acgtggccac cacccgcgac tactacttcg cgctggcgca      300

cacggtgcgc gaccacctgg tggggcgctg gatccgcacg cagcagcact actacgacaa      360

gtgccccaag agggtatatt acctctctct ggaattttac atgggccgaa cattacagaa      420

caccatgatc aacctcggtc tgcaaaatgc ctgtgatgag gccatttacc agcttggatt      480

ggatatagaa gagttagaag aaattgaaga agatgctgga cttggcaatg gtggtcttgg      540

gagacttgct gcctgcttct tggattccat ggcaaccctg ggacttgcag cctatggata      600

cggcattcgg tatgaatatg ggattttcaa tcagaagatc cgagatggat ggcaggtaga      660

agaagcagat gattggctca gatatggaaa cccttgggag aagtcccgcc cagaattcat      720

gctgcctgtg cacttctatg gaaaagtaga acacaccaac accgggacca agtggattga      780

cactcaagtg gtcctggctc tgccatatga cacccccgtg cccggctaca tgaataacac      840

tgtcaacacc atgcgcctct ggtctgctcg ggcaccaaat gactttaacc tcagagactt      900

taatgttgga gactacattc aggctgtgct ggaccgaaac ctggccgaga acatctcccg      960

ggtcctctat cccaatgaca atttttttga agggaaggag ctaagattga agcaggaata     1020

ctttgtggtg gctgcaacct tgcaagatat catccgccgt ttcaaagcct ccaagtttgg     1080

ctccacccgt ggtgcaggaa ctgtgtttga tgccttcccg gatcaggtgg ccatccagct     1140

gaatgacact caccctgcac tcgcgatccc tgagctgatg aggatttttg tggatattga     1200

aaaactgccc tggtccaagg catgggagct cacccagaag accttcgcct acaccaacca     1260

cacagtgctc ccggaagccc tggagcgctg gcccgtggac ctggtggaga agctgctccc     1320

tcgacatttg gaaatcattt atgagataaa tcagaagcat ttagatagaa ttgtggcctt     1380

gtttcctaaa gatgtggacc gtctgagaag gatgtctctg atagaagagg aaggaagcaa     1440

aaggatcaac atggcccatc tctgcattgt cggttcccat gctgtgaatg gcgtggctaa     1500

aatccactca gacatcgtga agactaaagt attcaaggac ttcagtgagc tagaacctga     1560

caagtttcag aataaaacca atgggatcac tccaaggcgc tggctcctac tctgcaaccc     1620

aggacttgca gagctcatag cagagaaaat tggagaagac tatgtgaaag acctgagcca     1680

gctgacgaag ctccacagct tcctgggtga tgatgtcttc ctccgggaac tcgccaaggt     1740

gaagcaggag aataagctga agttttctca gttcctggag acggagtaca aagtgaagat     1800

caacccatcc tccatgtttg atgtccaggt gaagaggata catgagtaca agcgacagct     1860

cttgaactgt ctgcatgtga tcacgatgta caaccgcatt aagaaagacc ctaagaagtt     1920

attcgtgcca aggacagtta tcattggtgg taaagctgcc ccaggatatc acatggccaa     1980

aatgatcata aagctgatca cttcagtggc agatgtggtg aacaatgacc ctatggttgg     2040

aagcaagttg aaagtcatct tcttggagaa ctacagagta tctcttgctg aaaaagtcat     2100

tccagccaca gatctgtcag agcagatttc cactgcaggc accgaagcct cggggacagg     2160

caatatgaag ttcatgctaa atggggccct aactatcggg accatggatg gggccaatgt     2220

ggaaatggca gaagaagctg gggaagagaa cctgttcatc tttggcatga ggatagatga     2280

tgtggctgct ttggacaaga aagggtacga ggcaaaagaa tactatgagg cacttccaga     2340

gctgaagctg gtcattgatc aaattgacaa tggctttttt tctcccaagc agcctgacct     2400

cttcaaagat atcatcaaca tgctatttta tcatgacagg tttaaagtct ttgcagacta     2460

cgaagcctat gtcaagtgtc aagataaagt gagtcagctg tacatgaatc caaaggcctg     2520

gaacacaatg gtactcaaaa acatagctgc ctcggggaaa ttctccagtg accgaacaat     2580

taaagaatat gcccaaaaca tctggaacgt ggaaccttca gatctaaaga tttctctatc     2640

caatgaatct aacaaagtca atggaaattg aactctagaa ttgtctctag aaaacatagc     2700

ttcttactga acttgaacat ttttacaaca ttcactggtt tttgttttgt tagctaataa     2760

tctataatag ttgagtatct ctgggaatgg ggagggaaat tatatgtaat agagcttaaa     2820

aataaagtgt caatttccaa gggctaaaaa aaaaaaaaa                            2859


<210>  1609
<211>  4818
<212>  DNA
<213>  homo sapiens

<400>  1609
agcggggggg cgccccctgg cggcgcaggg accgccccca acctcgcgcc gccgccgccc       60

gcctcagccc aacatggcga tgcacaacaa ggcggcgccg ccgcagatcc cggacacccg      120

gcgggagctg gcggagctcg tgaagcggaa gcaggagctg gcggaaacat tggcaaattt      180

ggagcgacag atctatgctt ttgagggaag ctacctggaa gacactcaga tgtatggcaa      240

tattattcgt ggctgggatc ggtatctgac caaccaaaaa aactccaata gcaaaaatga      300

tcgaaggaac cggaagttta aggaagctga gcggctcttc agtaaatcct cggttacctc      360

agcagctgca gtaagtgcat tggcaggagt tcaggaccag ctcattgaaa agagggagcc      420

aggaagtggg acggaaagtg acacttctcc agacttccac aatcaggaaa atgagcccag      480

ccaggaggac cctgaggatc tggatggatc tgtgcaggga gtgaaacctc agaaggctgc      540

ttcttctact tcctcaggga gtcaccacag cagccataaa aagcgaaaga ataaaaaccg      600

gcacagcccg tctggcatgt ttgattatga ctttgagatt gatctgaagt taaacaaaaa      660

accacgagct gactattaga agacacatta gtgcagaagc ttccaggctg tagagccctg      720

cttcccttct ctgacctcac aaagataaac atccttcacc tgagttcgtg gccatccacc      780

tctgctctcc cagacccagt gcctgtgact ttgagtagtt tgttctaaat gtggtgacaa      840

acaagtcatt tctgtaagac attgggtctt actttatgtc atttttagta acagaactgc      900

aggaagatga agacaatgtt gtaatcccag caagttgcta actgtgcgtt tctcccttct      960

tagaatgaat gtctccccca aaactggctg gcaccagctt catctgtgat acccttcaag     1020

aaatgttctc tggttttgtt ttatgctgaa agtagaacac aagtcacatt tcagatggag     1080

gctgtaaata tctggcattt tcttatattg ttttatgttt tcttgttttt ctcttgttgt     1140

ttttatctta ttttctttgg ggtttttttg taatgccttt gtacagctca tactttcctg     1200

ctgacatatc tgatcatctc tttcatgcag ttgccaatat tcataactga aaataatctg     1260

gtttatcata agtaaaatgg gaaacttgcc tctgtttttt gcaaggggag gtaaagagtg     1320

tttagtaatt acctatctta aatctttctg agttggtagt agattcatgt tcaaggaaca     1380

ggaaaaatgg aaaaacataa gtttaaatca gttcttttta aataactttt tattcttttg     1440

tataaataaa atttcacagg cttcaaattc tcatgcttta cttttaaacc cgagattgtt     1500

ttttcactta tttattcata tcatgcctta tggaaatttc tttttctgta ttttctctct     1560

ttgctggtat tcacctgatt aaatattgct ctaaaaatca ccatggcata tggaaagtct     1620

caaaattata ccaaaagtga taacttatgt cgttcttaag tggagtgaaa ggatagcatc     1680

agtgagagcc agtgttgccc accaggtctc cctttcttgg agggcttgtt ggggctgagg     1740

aatctgctag taatcgttac ctgcctctag tgctgtggtg aacttgcgac agggtctggc     1800

tgcacattgg aatcacctga gaagctttaa aatactcatg cctggatccc atccctagag     1860

actggggtac agcctagtta ttgggaattt ctttaaaaga gttcctggga ttctgataag     1920

aagccaggtt gagaaccact acattagaag actgaatggt ttaatttaca tcctatgtta     1980

tgattggtct aagggataag atttggggtc taacctttcc tttcactcta gttagtcata     2040

gtccttgact tatgcctata tctttgtaag aaatagtatg tttcatttgt gatagtattg     2100

gtagggctga atatggatgg catctactgt aaaacaagtc taccttgtca gatgtgcaaa     2160

agctttcact cttgttctca aataaacttt tgtgggtttt tttttttttt tttttttgac     2220

tctggctatt tagatctttg actgtgtctt tggtagcaga actccagtgt caggattttt     2280

aaggaaatag tttcttatat ttagattatt ccttaaaaaa aaaaatccta gaagcattct     2340

gtattttttg tctgttggtc tcctttgctg ggagggagga gtgggatgcc tacagtttcc     2400

ttccttttgg ggaaagcaca cagcagacct taaaatattt ttgactcttg ggctgggtgc     2460

ggtggctcac acctgtaatc ccagcacttt gggaggccga agcgggcgga tcacgaggtc     2520

aggagatcga gaccatcctg gcgaacacag tgaaacccca tctctactaa aaatgcaaaa     2580

aattagctga gcgtggtggc gggtgccggt agtcccagct actcgggagg ctgaggcagg     2640

agaatggcat gaacctggga ggcggagctt acagtgagct gagatagtgc cactgcactc     2700

cagcctgggc gacagagcga gactccatct caaaaaaaaa aaatattttt gactcttaac     2760

agtttgagat tgctagagat ggaatagtac tgctctgttg cgccactgca ctccagcagc     2820

ctgggcgaca gagcgagact ctgtcaaaaa aaaaaaaaaa aagaaagaat agtactgctc     2880

ttaaaaagat tatttacgta tttatgaaac tgcagtggga tgcctagttt ccttccctct     2940

gaggaaagca cacagcagac cttaaaatat ttttgactct catagtttga cattgctgga     3000

gacagaatag tactgctctt aaaaagatta tttaagtatt tatatatttt atttatttat     3060

ttatttattt atttatttat tgacaggatc ttgctctgtc acccaggctg gagtgcagcg     3120

gcctgatcaa agctcagtgc agcctcgaac ttctggggtc aagccatctt cctgcttcag     3180

ccttactagt acctgggact ataggtgcat gccaccattc ccagctaatt taaaacattt     3240

ttattttgta atgatggctt cttgctatgt tgcccaggct ggcctcaagc agtcctcctg     3300

gcctcaagca gtccttctgc cttggcctcc caaagtgctg ggattatagg tatcaagcaa     3360

ttctcctgcc tcagcctccc cagtagctgg gactacaggc atgcaccacc atgcccatct     3420

aagttttgta tttttagtgg agatggggtt ttgccatgat gggcaggctg gtctcgaact     3480

cctgacctca ggtaatccac ccacctcagc ctcccaaagt gctgggatta caggcatgag     3540

ccctggcacc tggcaatata gagtattctt gacatcttga cctgtgcagt aaagaagata     3600

attaaaatga gcgataaata gtctaagctt gaaagttaaa gagcctaagc ttgaaacact     3660

ctgtgactta gtttttgcat ttattctgtc ttctatgccc cccaacctta ctccaaatta     3720

atgaggcatt attttattta tttatttttt tgagacagag tcttgctctg tcgtccaggc     3780

tggagtgcag tggcacaatc ttggctcact gctacctccg cctccagggt tcaagcaatt     3840

attccgcctc agcctctcga gtagctgaga ctacaggcgc gtgctaccac acccagctag     3900

ttttttttta ttttcaatag agaccgggtt tcaccatatt ggccaggctg gactcaaact     3960

cctgacttcg taatccacct gcctcagcct cccaaagtgc taggattaca ggcgtgagcc     4020

actgcacccg gcctaatgag gcattattgc ttaaaaattc acatcaagct gggcatggtg     4080

atatgcacct ttagtcccag ctgcttggga ggcttagagg cagcaggatc gcttgaagcc     4140

agaagttcaa ggctacagta tgctatgatc atttctgtga atggccactg cacttcagcc     4200

tgagtaacgt agcaagacgc tgtctccaac agaaaattga catctgaagc cttgactaca     4260

gggggactat actggtttat gtgaagtgtg gggagagagc aggattgtgc ttctttgtac     4320

acatttgctt ctcccaggat agtgtcatag tgcctaggaa ggtgatgtgt gtgtcagata     4380

caatgatagt gaaaagaagg gattggaatt ttcatacctg tgtcagtcta aatgagcatt     4440

accttgtctg aattgtctaa gtggtaagct tcgtgatttg aaacagtttt cactttgaaa     4500

aactgcttcc gtggattaaa agttgtcacc actaaagtgg gctgtggtgg agtcgatgct     4560

gatcctcact tagggcagtg gcctccaagg ggaagagggc acacaggatg gctgggtggg     4620

ggtgggaaga aaagattagg cctttgattt atattcattt tgaggctcag ccttatttag     4680

tttctcactt tggatgtatt ttatatatat acatcaaata tacatcaata ttagttcatt     4740

agtacatgta ggtcattaat ttataaataa aaggttgaac cacaataaac tgctgataat     4800

tgtttttgat ctgtaaaa                                                   4818


<210>  1610
<211>  4900
<212>  DNA
<213>  homo sapiens

<400>  1610
ccttgccaag taacagcttt gctgtccaac atcgtgtgct gcttcgcgag aaagtcacat       60

tcggaccctt tggctagatt gcttattcat agggcttctt gactaaagcc cttggagcac      120

tgggtttttc ttgaagtata tgatcttaga cgaattttac aatgtgaagt tctgcataga      180

tgccagtcaa ccagatgttg gaagctggct caagtacatt agattcgctg gctgttatga      240

tcagcacaac cttgttgcat gccagataaa tgatcagata ttctatagag tagttgcaga      300

cattgcgccg ggagaggagc ttctgctgtt catgaagagc gaagactatc cccatgaaac      360

tatggcgccg gatatccacg aagaacggca atatcgctgc gaagactgtg accagctctt      420

tgaatctaag gctgaactag cagatcacca aaagtttcca tgcagtactc ctcactcagc      480

attttcaatg gttgaagagg actttcagca aaaactcgaa agcgagaatg atctccaaga      540

gatacacacg atccaggagt gtaaggaatg tgaccaagtt tttcctgatt tgcaaagcct      600

ggagaaacac atgctgtcac atactgaaga gagggaatac aagtgtgatc agtgtcccaa      660

ggcatttaac tggaagtcca atttaattcg ccaccagatg tcacatgaca gtggaaagca      720

ctatgaatgt gaaaactgtg ccaagcaggt tttcacggac cctagcaacc ttcagcggca      780

cattcgctct cagcatgtcg gtgcccgggc ccatgcatgc ccggagtgtg gcaaaacgtt      840

tgccacttcg tcgggcctca aacaacacaa gcacatccac agcagtgtga agccctttat      900

ctgtgaggtc tgccataaat cctatactca gttttcaaac ctttgccgtc ataagcgcat      960

gcatgctgat tgcagaaccc aaatcaagtg caaagactgt ggacaaatgt tcagcactac     1020

gtcttcctta aataaacaca ggaggttttg tgagggcaag aaccattttg cggcaggtgg     1080

attttttggc caaggcattt cacttcctgg aaccccagct atggataaaa cgtccatggt     1140

taatatgagt catgccaacc cgggccttgc tgactatttt ggcgccaata ggcatcctgc     1200

tggtcttacc tttccaacag ctcctggatt ttcttttagc ttccctggtc tgtttccttc     1260

cggcttgtac cacaggcctc ctttgatacc tgctagttct cctgttaaag gactatcaag     1320

tactgaacag acaaacaaaa gtcaaagtcc cctcatgaca catcctcaga tactgccagc     1380

tacacaggat attttgaagg cactatctaa acacccatct gtaggggaca ataagccagt     1440

ggagctccag cccgagaggt cctctgaaga gaggcccttt gagaaaatca gtgaccagtc     1500

agagagtagt gaccttgatg atgtcagtac accaagtggc agtgacctgg aaacaacctc     1560

gggctctgat ctggaaagtg acattgaaag tgataaagag aaatttaaag aaaatggtaa     1620

aatgttcaaa gacaaagtaa gccctcttca gaatctggct tcaataaata ataagaaaga     1680

atacagcaat cattccattt tctcaccatc tttagaggag cagactgcgg tgtcaggagc     1740

tgtgaatgat tctataaagg ctattgcttc tattgctgaa aaatactttg gttcaacagg     1800

actggtgggg ctgcaagaca aaaaagttgg agctttacct tacccttcca tgtttcccct     1860

cccatttttt ccagcattct ctcaatcaat gtacccattt cctgatagag acttgagatc     1920

gttacctttg aaaatggaac cccaatcacc aggtgaagta aagaaactgc agaagggcag     1980

ctctgagtcc ccctttgatc tcaccactaa gcgaaaggat gagaagccct tgactccagt     2040

cccctccaag cctccagtga cacctgccac aagccaagac cagcccctgg atctaagtat     2100

gggcagtagg agtagagcca gtgggacaaa gctgactgag cctcgaaaaa accacgtgtt     2160

tgggggaaaa aaaggaagca acgtcgaatc aagacctgct tcagatggtt ccttgcagca     2220

tgcaagaccc actcctttct ttatggaccc tatttacaga gtagagaaaa gaaaactaac     2280

tgacccactt gaagctttaa aagagaaata cttgaggcct tctccaggat tcttgtttca     2340

cccacaattc caactgcctg atcagagaac ttggatgtca gctattgaaa acatggcaga     2400

aaagctagag agcttcagtg ccctgaaacc tgaggccagt gagctcttac agtcagtgcc     2460

ctctatgttc aacttcaggg cgcctcccaa tgccctgcca gagaaccttc tgcggaaggg     2520

aaaggagcgc tatacctgca gatactgtgg caagattttt ccaaggtctg caaacctaac     2580

acggcacttg agaacccaca caggagagca gccttacaga tgcaaatact gtgacagatc     2640

atttagcata tcttctaact tgcaaaggca tgttcgcaac atccacaata aagagaagcc     2700

atttaagtgt cacttatgtg ataggtgttt tggtcaacaa accaatttag acagacacct     2760

aaagaaacat gagaatggga acatgtccgg tacagcaaca tcgtcgcctc attctgaact     2820

ggaaagtaca ggtgcgattc tggatgacaa agaagatgct tacttcacag aaattcgaaa     2880

tttcattggg aacagcaacc atggcagcca atctcccagg aatgtggagg agagaatgaa     2940

tggcagtcat tttaaagatg aaaaggcttt ggtgaccagt caaaattcag acttgctgga     3000

tgatgaagaa gttgaagatg aggtgttgtt agatgaggag gatgaagaca atgatattac     3060

tggaaaaaca ggaaaggaac cagtgacaag taatttacat gaaggaaacc ctgaggatga     3120

ctatgaagaa accagtgccc tggagatgag ttgcaagaca tccccagtga ggtataaaga     3180

ggaagaatat aaaagtggac tttctgctct agatcatata aggcacttca cagatagcct     3240

caaaatgagg aaaatggaag ataatcaata ttctgaagct gagctgtctt cttttagtac     3300

ttcccatgtg ccagaggaac ttaagcagcc gttacacaga aagtccaaat cgcaggcata     3360

tgctatgatg ctgtcactgt ctgacaagga gtccctccat tctacatccc acagttcttc     3420

caacgtgtgg cacagtatgg ccagggctgc ggcggaatcc agtgctatcc agtccataag     3480

ccacgtatga cgttatcaag gttgaccaga gtgggaccaa gtccaacagt agcatggctc     3540

tttcatatag gactatttac aagactgctg agcagaatgc cttataaacc tgcagggtca     3600

ctcatctaaa gtctagtgac cttaaactga atgatttaaa aaagaaaaga aagaaaaaag     3660

aaactattta ttctcgatat tttgttttgc acagcaaagg cagctgctga cttctggaag     3720

atcaatcaat gcgacttaaa gtgattcagt gaaaacaaaa aacttggtgg gctgaaggca     3780

tcttccagtt taccccacct tagggtatgg gtgggtgaga agggcagttg agatggcagc     3840

attgatatga atgaacactc catagaaact gaattctctt ttgtacaaga tcacctgaca     3900

tgattgggaa cagttgcttt taattacaga tttaattttt ttcttcgtta aagttttatg     3960

taatttaacc ctttgaagac agaagtagtt ggatgaaatg cacagtcaat tattatagaa     4020

actgataaca gggagtactt gttccccctt ttgccttctt aagtacattg tttaaaacta     4080

gggaaaaagg gtatgtgtat attgtaaact atggatgtta acactcaaag aggttaagtc     4140

agtgaagtaa cctattcatc accagtaccg ctgtaccact aataaattgt ttgccaaatc     4200

cttgtaataa catcttaatt ttagacaatc atgtcactgt ttttaatgtt tatttttttg     4260

tgtgtgttgc gtgtatcatg tatttatttg ttggcaaact attgtttgtt gattaaaata     4320

gcactgttcc agtcagccac tactttatga cgtctgaggc acaccccttt ccgaatttca     4380

aggaccaagg tgacccgacc tgtgtatgag agtgccaaat ggtgtttggc ttttcttaac     4440

attccttttt gtttgtttgt tttgttttcc ttcttaatga actaaatacg aatagatgca     4500

acttagtttt tgtaatactg aaatcgattc aattgtataa acgattataa tttctttcat     4560

ggaagcatga ttcttctgat taaaaactgt actccatatt ttatgctggt tgtctgcaag     4620

cttgtgcgat gttatgttca tgttaatcct atttgtaaaa tgaagtgttc ccaaccttat     4680

gttaaaagag agaagtaaat aacagactgt attcagttat tttgcccttt attgaggaac     4740

cagatttgtt ttctttttgt ttgtaatctc attttgaaat aatcagcaag ttgaggtact     4800

ttcttcaaat gctttgtaca atataaactg ttatgccttt cagtgcatta ctatgggagg     4860

agcaactaaa aaataaagac ttacaaaaag gagtattttt                           4900


<210>  1611
<211>  9186
<212>  DNA
<213>  homo sapiens

<400>  1611
gcgcgccccg gcgccgcgcc cggccgggag ccgcctgttg atcgccgcgc tcgccccggc       60

cacggcgccg cccctgttct cccggccccg ctccaccggg gctgacggac tgacggccag      120

cacagccggc tccgggatga gcgcacggac ggtattctga agtctcagga aactggacca      180

tttaaatgtg catggcccat gagaaaggct tataagaagc catggcactc ccctttcaaa      240

aagagctgga gaaatacaag aacattgatg aagatgagct tcttggcaaa ctctcagaag      300

aggaactgaa acagttggaa aatgttctag atgacctaga tcctgagagt gccatgctgc      360

cagctggatt tcgacagaaa gaccagacac agaaggcagc caccggcccc tttgaccgcg      420

agcacctcct catgtacctg gagaaggagg ctttggaaca gaaagacaga gaggactttg      480

tgcccttcac tggagaaaag aaagggagag tctttatccc taaagaaaag cctatagaaa      540

ctcgtaaaga agaaaaagtg acccttgacc cagaactgga agaagctttg gccagtgcct      600

ctgacaccga actctatgat cttgcagctg tccttggagt acacaatttg ctcaacaatc      660

caaagttcga tgaagaaaca gccaacaata aaggtggcaa aggacctgtc agaaatgttg      720

tcaaaggtga aaaagtaaag ccagtatttg aggaaccacc aaatcccaca aatgtggaaa      780

taagcctgca gcagatgaaa gccaatgatc ctagcttgca agaagtcaac ctcaacaaca      840

ttaagaacat tccaattcca accctgaggg aatttgcaaa ggctctggag accaacactc      900

acgtgaagaa gttcagcctg gccgcaactc gcagcaatga ccctgtggcc attgcttttg      960

cagacatgct gaaagtaaac aagaccttga caagtctaaa catagaatcc aattttatca     1020

ctggaactgg gatcctggcc ctggtagagg cactgaaaga aaatgacacc ttgacagaaa     1080

tcaagattga caaccagagg cagcagttgg gaacagctgt agagatggaa attgcccaga     1140

tgctggagga gaattcaagg atcctcaagt ttggatacca gtttaccaag caagggccac     1200

gaacaagggt ggcagctgcc atcacaaaga ataatgacct ggttcgtaag aagagagttg     1260

aagcagaccg aaggtaaact tccttgagga gaagtgaagt ttcactgtgg tatggccatt     1320

gaaaaacaaa aactcttctt cttccccatc aggaccattt tatcaaagtt cgttcatttc     1380

cgttaaccac ataactaata atttaattgt tattcttttt tagcactact tatttatctt     1440

ggattttgta atatatgcaa ttgttttatt tgctcatggg cacttctggc aacttgacaa     1500

atggaccgat gcagatttta gagagtgacg acatggaaaa tgaatttaac cactttctta     1560

ttgggttgtc ttgctttctt acatgaactt gtttttttaa tcactgaaag gaatttagtg     1620

tataatatgt gtttgtaact gtgattatga tagaggccta tctctgttta catgcatagc     1680

tttgagttag gctaaataca tcagaagtgt tctactgacc acataagaag ttagtattgc     1740

caatctttca ctgcatgtga aaatgtgacc aatttagcac aaattctctc ttagttccag     1800

aaaaatcagt aaatgcacat gccctgttga ttggagatca gtagtgtcat cttcataaag     1860

caagacaaca ttatgacact ttaaaacagt agcaaagaag tctatttatt aacccacaaa     1920

tgtagcatca agccagactc acaggtagca aaatgaatta cacacctact tttactgact     1980

attcaacata aattgaatct ttaacatgac tttaaaggct atttacaaag ctgttttaaa     2040

gtttttcaaa catgatagaa attttctaaa ttttagtaag agagaagctt ttaaaacagt     2100

acattcctga ataaaacaac aatattgtat cttaatcaag gctgtctgat gcagatgatt     2160

gcattttttg gcaaatttta gaagcattta ttgctttgtc tttagtgtaa caagatcact     2220

ggattaaata taaacattca ggttaattat ctagattttt gtccacagta tatgatccat     2280

ccagacattt gcaaacgtca ggagaaaaat gtgaattatt tatccagatg catgtcatct     2340

caaggacaaa gcctgtgaaa gtacaagtga gatggttgca ttgtagtatg cattaatctt     2400

tcaatgtagt ggtgtaaaaa tgcagtgcta aactaatgaa gcaggtgact gcagcctttg     2460

gctcaagctc acaactctga taactgtcag tgcctgaggt tgtgattggt gacattctga     2520

cactgcccaa ggcaactcac cctctattcc tcctttctcc cctccctttc ttccaattca     2580

ttgtcttttt tttcctcttt tctctgtaat ttgttactaa acaaattcca gaatttgttt     2640

agtagctgag tgttcctgag ttgcctagta gcaataaaac aagtgaatag gaaaataatt     2700

aatatattat tctatttagc ttgtaaaaca catggaatct gtttaagata gcccttgtaa     2760

aattgaacat ttacctgtat tgtaagtacc cacatctgtg tctctgaagt cctttgaaac     2820

atctcattat cttgaaattt ttttaatgtt tgagaacacc ataagcagaa tattctaaca     2880

cctttggccc ctgaaaatcc tttaattagt ttatggcttc atctccttat ctatttaaaa     2940

aacatagtaa ataatgttta tggttttcag tctgattttt ccttcccttt cacccattta     3000

ggtgtgatgt gttggagtca acttgtacag gcttgccaac tgttatattt tcaagaattt     3060

tgcaaactgg ttgttcaata cagccattat ttaaaattaa atgatgtgca cttacaactg     3120

aatgaattat attaaggaca gaagtaacaa atactgtact caaaaatctt acattttact     3180

attttctaac ctcttagatt atttacatct agtaggtatg tatgtagaaa tattaccaaa     3240

cagtatgcta ctgaacgtat cctctcaact ccatgttcac taccttcttg ttactacagt     3300

ggcttgaaat tggccatggt agaaatattt acaccacaga aattagcaat atgtaagaaa     3360

ttggggtttt ctccctctcc agattgctgg ttgataaaca ttcatcagca caccactggg     3420

tgaaattata cattttttta tacatatgtt tcgcttatca tgttgccgaa gggaagaaca     3480

tttctcttag atgtcttttc tcctctttgg atttgttaca aacctgttta agtgctgagt     3540

ccctgacctg cctctccaag taagcctttt tccttttttt tttttttttt cttactctca     3600

ttcttgcctt gactcttaaa atcctggacc ctatagagca ttccttgcag ccccacagtg     3660

ctgtgggctg ggggctaaag cagttcttgg caaactctgg cagaaagcaa gaaaaaaaga     3720

atcagaattc aatcatggct gtttcttttg tacaagcagt tgttgatagt attaaagcaa     3780

gataatggga cattatcaaa aatatagcac tgtttttacc ttatgaaata gttgggttgc     3840

atgcaacaga gtctatgaaa tcaaatgttt tttactaatc agtttgtttt cttattacct     3900

gtgtttttaa agtggcttga aaggtggcat ttccatgagt gtgcacatat tgatgataac     3960

ccttagaaaa acatacactt gaggagccta tccatcattt aattagccta ggacttcatc     4020

tccctctctg cccaaagtgt ggaagtggta gctctttcat gatcatgggc acagttaatc     4080

ctttgctatc cattgtgatg gggcataatg tatataaaat atttttctat gtatttgttc     4140

tgccagatac tgtgttgaga tatttggcaa tatctggata actgactgaa gggagataac     4200

ttctccccag gcctatctcc ctcccccttt tagagttgtg caggtccact ttaagtgtaa     4260

aatcactcac ctggacttgt gggcttgtat caccaacatc tattatggca catgtagatg     4320

acatttagga gaaaaacctt agaagtctag aaatcatatg attagttcag cactgcagct     4380

ccccatctgc ttatagtgta taactggaag ctctttcatc ctcatcagca tgattaaatg     4440

acttcgtttc tttcatcttt ggagggtata atgtaaataa gtgtcgtgtg tgtatgtgtg     4500

tgtgtactgt cagatatcta actaggtatt tggctacatc tggacaactg attgaaggga     4560

gatgctctct ccccagtcct cttcccttgt cctttttaga attgctgcag gcccaggtta     4620

aatatgaaat tactccctag gctttgcagt ttatgttacc aaccaccaca ttttatagct     4680

atgtagagga tgactcttag gaaataaata ttagaagcct agaaatcatt tagttgttct     4740

agcaccaaat ctatccattt gcctaatgta tttaacattc catcctcatc aacatgatga     4800

agcccctttc ttccatcttt gtagggcaca ttgtatataa atattttgta cataaagatc     4860

atcaaatacc ataatggggt atttggcttc atctggaaaa ttgactggag ggagatgctg     4920

tctcccagcc ctgcttccct cgtccctgtc caagttgctg caggcccagg ttagaagatt     4980

accaacctgg aggggcatgc agttcatctt acaataaaag cccattcatt taaaaactca     5040

gaaatcatcc cagtgcctgt actcctcaaa ccaatttccc taagggaaga ctggcacacc     5100

agcccaaaga gcaggtgctt ctcttccaac agaaacatgg cccctgacag ggcaccagca     5160

ttagggaaac caatgtcctc cgaatagctg ccatgagaac atttcagatg ctcaaactga     5220

aaattcttaa aaccaatatt aagcatcagc atgctttaag tgtaagatag ccctttggaa     5280

tttacaaaca catgtgcagc tatttccttc ttcacagata tgatgtactc agccccctcc     5340

taggcactac gaagaagaca gaggaagcat aaaaattctg gactaatata attttatatg     5400

tgtttctgag attggggagt agactgagtg ccttttttac aaagaagatc ccatatttaa     5460

ttcaagtatt tatagcatca gcaaaaatgg gcagagggcg ggaagttgag aacactaggt     5520

tctgtgctat gttacctgta ttcagtagaa gtgtttctgg agtcaggttt taagtcatga     5580

tcctgaagct tccttcccct cttccactaa tgatgcaata atagctgttt tcattttaac     5640

gagcagagaa ctaagaggaa aggtcctagc tctgccttcc acttgcagct tccctttacc     5700

tcctcttatt gctttcatct caaatatccc tgctactcaa ccaatcctaa agctaaagta     5760

ctgagatgca cacaaaggaa aggtgtgaga gtgcttggaa gcatccagct gagcccactg     5820

gatgaaaatc agacgatagg gcctcctgtt gtaatatact agccagagaa aagcgccaag     5880

aacttcaggg atattattca ctgctttatt gctccctaac cctagatcag attggatttt     5940

actttgtagt tcaggagtta agaagtcaaa ttgctgaccg aggtggggaa ggatgatgga     6000

aattaaaggt ttacatttgt ttaatggcag aactgagatt tgctcagctt atctctttcc     6060

catctgtctg taatagcaat gactgaataa tcagtagacc aatggaagag gagttgcaag     6120

tttaaatttg taacctgact ctgggttctg ttctaggaat agtgcatgtt ttagaggctt     6180

tgccagttgg gatacattgt tgacttgggg gaggatgaag gagagaactg atgacctaga     6240

catagaaaag agtagttaac taactagatg ttcttctgat ctcttccatg gtagacattc     6300

tgagcacatt ggcccagtta gttggtatgg tgaaggggca ccgtactaac agatttggag     6360

actgaaacct aatcccatca ccaacactta gcaggtatat gatcatgggc aattcattca     6420

attgcctgcc aattatagac tatatagggg gaagagcact ggatttggag tcaagaaacc     6480

tggacacttg gctccacact tccttagctg ggtaactttg ggcaaaccgc ttggtctctc     6540

aagcctaagg ttcttcagct ataaaatggg aataatactt cactaactac ctcacagagt     6600

tgtggtaaga atataatcag ataactggat aaaaacacta tataaactgg aaagcgccgt     6660

acaaatgtga gagatcagtt ttattatcaa atcactgttt tccactgcct cttgaatcgg     6720

ctttattcta accaaccatt acatctttct catcttttgg agtatgggta attgaggctt     6780

gggtgtgtca tcagggactg gagttatttc agctcccatg tagaggtggg agaggtggtt     6840

gatggggcag tggaagttag ataccagcga tgtatatggt aggacatttt cctgggtcac     6900

tttgacagta ccttgggaaa ttgtcagtcc ttgcagaggg cctaggctgg gcacaaggga     6960

gaaagcgaac agttgactaa gaattgaggg gagggtctgg agcgctactg ccctcctgtc     7020

attgctgtgg gtgggagagg ctaagacttc aggtttgact ggaggcctag gagagaagag     7080

tgtccttagg gtttcaagaa ttttaatgcc tagcagctga gtaacaggca ttagttctga     7140

tagatagtga aggggagaaa gtgccacctg ttgtgagatc acctctccag ggcagcagct     7200

gccttgttat caccagcaac cttagccctg gtcagtaata tttctgctaa gaaaggtttt     7260

gaagcatggc ctccaatgac tttcataagc ccttggaggc aggactgtgt ctcatccatc     7320

tttgtatctt cagtaccatc ttgtaaggtg ccttgtacat agtaggtgct taatgaacaa     7380

atgttgcttg aatttagctg tcgtccagcc ccacagagtt atgctccatt tgccaccatg     7440

tgatattttt gagaaacaat agtgatttgg atgccagctc tatgtgactt tgggcaagac     7500

tctccatcta tcttgtcttc atttcatctg taaaatgaag tgagtagatt caatgctccc     7560

taaggtccct tccagctcca atacttgaca agcttgtgat tctaaatcgt ttccgttgcc     7620

tctgaacatg ggtgagtaat gcctccactg cagctgtttc tctccaggag gctttgttca     7680

gaggaggtct gactattgca cagccagttt tttcttcctc ttcagcagtt ctttactgtc     7740

ttcagaatgg ttctggataa gcggcctttt ctgaaaggat atttaaaaat atatactatt     7800

taggctgggc ccagtggctc atgcctgtaa tcccagcact ttgggaggtg aaggtgggtg     7860

gatcacctga ggtcaggagt tcaagaccag cctggccaac atggtgaaac cccgtctcta     7920

ctaaaaatac agaaattagc tgggccctgt ggcaagagcc tgttatccca gctactgggg     7980

aggctgaggc aggaaaatcg cttgaaccca ggaggtggag gttgtagtga gccgagatca     8040

caccactgca ctccagcctg ggtgacaaga acgaaactcc atctcaaaaa ataaaataaa     8100

atatatacta tcttgctcct cagaaccagt ggggaagaag agggaaggca aagaaagaaa     8160

ctgagcatag taaacacagc atttttttgt aggctcttat ttaaaatgtg tgtgtgtgtg     8220

tgtatgtgtg tgtttctgag taagtattga ctgggaaaaa gagagaagtc aatcaaaagt     8280

atactgtgca attgagagag gctggcccaa gatttaaaac ttcctgtggg taatctaact     8340

gtgagtagat aggaatcggc catatgacga aatgagatca ataggaaatg tgctttttga     8400

ggaaatttta ttttagtacc aaatgttgcc agtgacaatc ttcagttaag aagtaagtta     8460

ttctgaccta aaattcttat ctctgccact ttggtttaaa aacaaaaacc cttatataca     8520

tggaatagtt atattttaat taagcattta ttttagttgt tttcatccat tcaagcaaaa     8580

tgaataagca gcatttttca ttgcacttaa aaatgtaaaa tacctgcatg ccactaatct     8640

gtaacatttt accagttcag atgcctgtaa tgtgtgactt tatgtgtgtc tgtgttgttt     8700

tgaagagaat aaaggaaata atactttgca aactgtttaa acaagtgttt aaacttctat     8760

tggcaacatt tattgggcta agcagttatt gaaaactccg catagtttta ttttccattt     8820

gaaacttcaa tcaaatcaag actattatat tcattaggga attaaagact aatttgcttt     8880

ttaaatgtga agttgaacac tgtgtggaaa gtaaatgtgt gatgaagcaa aatgtataaa     8940

gtatgaaata ttatactttt accctggata attattcagg accccagttg gcccaaatag     9000

gtgcaatttt taatcctttg aaattagcca gccagaccta atgctaaggt aaatgtaaac     9060

tgttttaatt aattaagatc tttctgcttt cgaaggtata atgtatctat ttctgtcagg     9120

aatgatattt ccaaatgaaa atgtaaagaa cattgggaaa taataaactt tcctttcaaa     9180

gtaaaa                                                                9186


<210>  1612
<211>  666
<212>  DNA
<213>  homo sapiens

<400>  1612
gggtggctta gcactgcagg gctctgcgcg ggaacgctaa cctggtccgg agcgagtctg       60

ggtctcagcc ccgcgaacag cctttcacga gtcttcaagc tttcaggcta tcttctagtc      120

aagatgagtg ataagccaga cttgtcggaa gtggagaagt ttgacaggtc aaaactgaag      180

aaaactaata ctgaagaaaa aaatactctt ccctcaaagg aaactatcca gcaagagaaa      240

gagtgtgttc aaacatcata aaatggggat cgcctcccaa cagcagattt cgacattacc      300

tgagagtctt gattttaggc ttgttttttg taaacccatg tgtttgtaga gattttaggc      360

gtcttcggat atcttctcac ctatgttccc tggctaagaa gtcagaggta gccaatgttt      420

ccttaaattc atttttaaac ttaccattgg tgcatatgtt ccagatggca gatgctgtca      480

ataatctcac cattgatgac ctttgtgtat gtagttcttg catcctatac tggataagcc      540

tgttttaacc tgctatgatg ggtgcttcca ttgcttcata atcttcatga agttgcatgc      600

ttttgcagct tttcacagtt tatttgcatt tctaatgtag taataaagta accaatataa      660

tcatta                                                                 666


<210>  1613
<211>  4018
<212>  DNA
<213>  homo sapiens

<400>  1613
cagcggccga aaacttcagg ttccaggctg ctgtgcggct aaatgcgact ccatctcccc       60

cgacccaagc gcgtaatggc cgctggctat cttgggggag ccagctgttg gactatgccc      120

cactgccagg aaacaggcgc cggaaggttc tctgacaaga tctcgctttc ctagggcggt      180

gaaggcgttc aaaggtcggg aaggggcgct gggagaagcg gggcagcgct gagccatgct      240

cgcgaactgt gggtctgtct gtgaagagac ccagtttcgt gggaccacgg tggcgcctgc      300

gctgggaggt gagcttgtga cagagcgaaa actacaattc ccagcattcc tgtggtgcca      360

gaactacctt gcccgaaagc ctgtgcgaga tttaccccgt cttccgcctc cctcccaccg      420

gaaaactctg aggacatgaa tagtcgccag gcttggcggc tctttctctc ccaaggcaga      480

ggagatcgtt gggtttcaag gccccgcggg catttctcgc cggccctgcg gagagagttc      540

ttcactacca caaccaagga gggatatgat aggcggccag tggatataac tcctttagaa      600

caaaggaaat taacttttga tacccatgca ttggttcagg acttggaaac tcatggattt      660

gacaaaacac aagcagaaac aattgtatca gcgttaactg ctttatcaaa tgtcagcctg      720

gatactatct ataaagagat ggtcactcaa gctcaacagg aaataacagt acaacagcta      780

atggctcatt tggatgctat caggaaagac atggtcatcc tagagaaaag tgaatttgca      840

aatctgagag cagagaatga gaaaatgaaa attgaattag accaagttaa gcaacaacta      900

atgcatgaaa ccagtcgaat cagagcagat aataaactgg atatcaactt agaaaggagc      960

agagtaacag atatgtttac agatcaagaa aagcaactta tggaaacaac tacagaattt     1020

acaaaaaagg atactcaaac caaaagtatt atttcagaga ccagtaataa aattgacgct     1080

gaaattgctt ccttaaaaac actgatggaa tctaacaaac ttgagacaat tcgttatctt     1140

gcagcttcgg tgtttacttg cctggcaata gcattgggat tttatagatt ctggaagtag     1200

tattaatgct catcctgctg tggctgttgg cttcttagaa caccaaaccg ggagagattt     1260

actttgaaca ttgtcagttg cagcaaaaat ttactacaca agattattcg aagtgtatac     1320

ggactaaaag aggaagtgtt ttagaatgag aagagatact gtgtctttat tgtgtgtgtg     1380

tgagtgcagg tgtgtgtctt tattatattg aaaagctgtc actcagacct ggtttgagat     1440

agaagagcat tttgtccttt tgatagttaa tagaaattga accagagttt tcttatgttt     1500

gcttgaacag ttgtgtaaat catacaggat tttgtgggta ttggttgaat atttgtaaac     1560

cattccctag cctacatatt tattactgaa ttaactttcc tgataaccat tgcataatta     1620

catttttcta taaaatgaaa gattattaca acaaagttgt gtgggttttc aaagtgactt     1680

accatatagt tggagattga tttctttttg gtaatgaact aaaacaataa attttaaaat     1740

gataggccag gcgcggtggc tcacacctgt aatctcagca ctttgggagg ctgaggcggg     1800

tggatcactt gaggtcagga gttctagacc agcctggcca acatggtgaa accccgtctc     1860

tgctaaaaat acaaaaatta gccaggcatg gtggcacatg cctgtaattc cagctactcg     1920

ggaggctgag gcaggagaat cttgcagtga gccgagatag caccactgca ctccagcctg     1980

ggtgacagag caagactcca ttacctaaat aaataaatgt gtgctttagt gcaaattaca     2040

acacttaata tgaaatctgt agagttgcta aatattgagc tctgattatt acatgtattt     2100

tttaaatatt tgatactcaa aaaccagttt atccctgctt cttaatgtag tttaagttaa     2160

cccatcttaa atttattaca taaaacaaag cttttcttaa tgacttcaat tcagcaaaca     2220

ttgatatcta gtacctactc tcaagaaact cataggaaaa tttaaattcg tattttgttt     2280

tgttattaga tatatttttt cttacaaagt aatatctatt agtaaatcat atgtaatttc     2340

aaagaaattt taaaatatcc ttttcatctt agttcttcag tcttacccag atcaagaaga     2400

caagaccaga aagtaaacat tttgagttca taatgccttg gtaatagcta taaaagtttg     2460

acaatcatta ttcaaaatag ccttgtcatt tgtttagcta taaacaggga atctgcagta     2520

tagagcagtc aagagattgg tccatatggt ccagtgagtg agagtcaggc tttccaacta     2580

tattttcctc aaaaatctaa ctgctggttt gttttcaaaa gaaaaacctt gacattatcc     2640

tgttacattc tgattcattt ttatctctat tgcctaagag agttcttagt atattataga     2700

ttaattttca ctgagtcaat taataagtta ccatatatat taaagtccac tgtaacaaag     2760

tatactgcat ttgttcagtt aaccaatatg actgcctgct atatgccaaa cagcatgcta     2820

gtccctgtgt gcacagagat gaacatggtt tcattctcat tgaattgaca atcttaagga     2880

gagagacata aacaagtaaa ttattggttt gttaagattt aaaatattct aaaatattaa     2940

gagggaatgc gtctttcctc catgtgaagg aagctccagt agcataacac tgtcgtcact     3000

cttcatcccc ttatccactc tgccctaggt aaagtgactt gcccaattgt aaatctggaa     3060

ggagaaacaa ggtgcaatta gcccacttcc tccccactcc tgtttgggac cagcccatct     3120

gaagagacat tcattctgtt ctgcttctat gggatcaggc tctgcctctg caggatgagg     3180

cctggcccag tagagcaatg cttgagacag ggtaaatctg tccagttcta gagttcagtg     3240

ataagaagct tactggcctt aagatgaaac ccatattctc ttgctgagca cagtggcaca     3300

catctatagt cctagctgct tgggaggctg cggcagcagg attgcttgag ccaaggagtt     3360

catcaaggct aaagtgtacc atgatcatac ctataaatag tcactgcact ccagcctggc     3420

aacacatgag accctgtctc ctaaaaaaaa acttctccaa tagttttatc agcaaataaa     3480

ggtgtttttt aggcctctat attagtttat tcattcttca tcttagttat attcacaacc     3540

cagaatggaa aggaggtatg ccatttattg gaccttctca agccccaaca aataaatata     3600

cttattccca ggttatacag ccactaaata ttaaatagat ctgcgttctt tctcattgta     3660

ggggtttagc aaacaaagtg ctttgtatcc aataacagaa gaatagaaat atgcatacca     3720

taccctgtcc ccattacttt tagatcctat atcctttcca tgaaacttca ttttgatggt     3780

ggttctgggg ttcaggtaaa tttttgtttc agtgatggaa atatatgaaa taaggatgag     3840

aggattgtgt ttctatatgc cttaaaacta tacctctatt ccagcacttg cacttcacta     3900

tgaaacagca attatacgta tctttttcct acactaaact acaagttctc agaaggcctc     3960

tagacacatg tgaggtactt gttaaacgcc tgtggaataa atgatactca taaatctc       4018


<210>  1614
<211>  5762
<212>  DNA
<213>  homo sapiens

<400>  1614
attgggtaca tgcgcagtgc cgctcgcgcg ggccgcgcca atcctgcagc gccttcaaca       60

ggtttcgggc ggcgaattcc agttctccgg gttttggggc tccctgcggg aggcagtgct      120

ggatctggga atctctagga aaggaaagag caaaggaggg gaaagatggg gggctgcagg      180

aaatttggtg agcggcctcc acctaaacga cttactaggg aagctatgcg aaattattta      240

aaagagcgag gggatcaaac agtacttatt cttcatgcaa aagttgcaca gaagtcatat      300

ggaaatgaaa aaaggttttt ttgcccacct ccttgtgtat atcttatggg cagtggatgg      360

aagaaaaaaa aagaacaaat ggaacgcgat ggttgttctg aacaagagtc tcaaccgtgt      420

gcatttattg ggataggaaa tagtgaccaa gaaatgcagc agctaaactt ggaaggaaag      480

aactattgca cagccaaaac attgtatata tctgactcag acaagcgaaa gcacttcatg      540

ttgtctgtaa agatgttcta tggcaacagt gatgacattg gtgtgttcct cagcaagcgg      600

ataaaagtca tctccaaacc ttccaaaaag aagcagtcat tgaaaaatgc tgacttatgc      660

attgcctcag gaacaaaggt ggctctgttt aatcgactac gatcccagac agttagtacc      720

agatacttgc atgtagaagg aggtaatttt catgccagtt cacagcagtg gggagccttt      780

tttattcatc tcttggatga tgatgaatca gaaggagaag aattcacagt ccgagatggc      840

tacatccatt atggacaaac agtcaaactt gtgtgctcag ttactggcat ggcactccca      900

agattgataa ttaggaaagt tgataagcag accgcattat tggatgcaga tgatcctgtg      960

tcacaactcc ataaatgtgc attttacctt aaggatacag aaagaatgta tttgtgcctt     1020

tctcaagaaa gaataattca atttcaggcc actccatgtc caaaagaacc aaataaagag     1080

atgataaatg atggcgcttc ctggacaatc attagcacag ataaggcaga gtatacattt     1140

tatgagggaa tgggccctgt ccttgcccca gtcactcctg tgcctgtggt agagagcctt     1200

cagttgaatg gcggtgggga cgtagcaatg cttgaactta caggacagaa tttcactcca     1260

aatttacgag tgtggtttgg ggatgtagaa gctgaaacta tgtacaggtg tggagagagt     1320

atgctctgtg tcgtcccaga catttctgca ttccgagaag gttggagatg ggtccggcaa     1380

ccagtccagg ttccagtaac tttggtccga aatgatggaa tcatttattc caccagcctt     1440

acctttacct acacaccaga accagggccg cggccacatt gcagtgcagc aggagcaatc     1500

cttcgagcca attcaagcca ggtgccccct aacgaatcaa acacaaacag cgagggaagt     1560

tacacaaacg ccagcacaaa ttcaaccagt gtcacatcat ctacagccac agtggtatcc     1620

taactaccgt ctttttgcta ggacttaaac tgacttgagt gtggcaaaaa gttaacaaaa     1680

aaggagaaaa aatgaacaat cgtttgtggt ttcttgggaa aacttttcat accaggtgat     1740

actattcaaa aaccccgttg tctccctgca agtgctgatt tgaaatgcag aagccacagt     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa aaaaaaatca aaatgtataa atattggaaa     1860

tcaagttttt cagctgtttt gttggttggt tggttggttt ttgtttggtt ttgtttaaat     1920

gggcaagaag taaataatgt ggctggaata caagttgaac aaactagaag acacaaatct     1980

aacatagttt ttatggacca aggaacttgt atattgtata agctttagta aaaggtacat     2040

tttcaccata ccttttttta tatcacggta ttatagtaca ccttgttacc aaataggttg     2100

ttctcttccc cacccacctt tgagcttttg ctctaaaata cattcaggtt ccaagcctga     2160

ccatccttgt ttaatctatc atactcttcc aggttttttt tttttggtct aaggctggaa     2220

cttttttctt ttttttcagc tgaagtctta tgacttttca tgagtcaaaa ttgtttggat     2280

ttcagcaagt caaatcttgc aaaggcctgc atattttttt taagattata tgaagtctgt     2340

gcaaaagctt taaaaaaatg cctctgcctt gcctgcaata catgcaatgt atgttaactt     2400

agtctctctt ctcagacact gttggtagtt atttctgtgt tttccttttt ttaaaaaaaa     2460

atatggactt attgtggtta tctgagaggt tctaacattc acatgcaatt tggtgtggcc     2520

atttagctat taatgagtta atggcgcaga acttgttgat atttgaagtg ttctctcccc     2580

ttttcccatg acgtaaatac ataggtgtgt tccaggattt gttcaggttt ttcccccctc     2640

ctaatcttgt acataacttg tattatgtgt aagttaaaca ttttattttg aacttggaat     2700

gttcccagtg atttcattca gcagggtatt ttctgccttg ttggcaagtg acaaaaaata     2760

tgggaagtat ttgctaccag ttggtagatg gtgcccttaa tggtagaatg aggaaaatgt     2820

ccgcaaaagc atgttttatt atctttactt ttttgggggg ttggaggggg tagcctagcc     2880

agaacatcat tgtaatctta aaacataaga tgcttttatt agatgatcaa ctaaaatagc     2940

tggaagacag tactttagaa acagatagtt gtaagattat aaaatgcaaa tgtaacttat     3000

gttttcattt ttttctctgc cttttttgtt tgtttgtttt ctcttttcca gtactgagca     3060

tctccacaaa tgtctcctaa ctcagaaaat gtttcttttc ttttcagttg agatttggtt     3120

gcattcaggg ttgtaggttg gccttgcttg ctaaccccgc cggttttacc gtgctttcat     3180

tcctgaactt tgtttatgcc tttgtttggt ttcttcgaaa ttgcagcaga ctcattgggc     3240

tacatttagt acaggaacca cgtgtgtaat gttatacaac acagtctagt aatacaatca     3300

tccctcttag agtaaaaact acctctagat tgtggtaagc ttttactgtc ccataaaaca     3360

ggagccacag taccttatga atgcaaaact gtaacttcct acagtgtttc cctacagaac     3420

attgtctttc tggtgtcctg ggctgttttg aaaaagtttc cattaataga ctttttagaa     3480

attattatta gtagcatttt ttttccagct ttgctgtctt catcactcac tctatgctca     3540

gactatgcca ctgtaaatat tcttcctaac atctttaaat cgccttttcc tcagttttca     3600

aggggaaggt catttgtaaa gcacgttagg tggttaaatc agttattgcg gttttctctt     3660

actgcaagcc tttttaatca cccccaggct gcattttatt ctatatcgcc ttttttcttc     3720

aaatctgctc caatcactca cttctctctt ataagctaat cctgcctcac accttaaatc     3780

tgtttcagtg atcaagggca gaactcattg tggccttatc tttctttgtt gtaattgttc     3840

actgtctctt tcttacagac cacttatttc tgagtagtag ttattcctct ctatggagtc     3900

atggcaggaa tcattacaca gtgcttttgt tcagagcatg gacatgttcc tagtgctgct     3960

ttgctttaac ggccacaagt ttcctccact tcctaggttt ggtatttagt taaggaatca     4020

tattaaatta accaataaca aaagagatac ttttgaagaa caaactattc cttacccatt     4080

tttgtagctc aaaaataatt tttcaagttc atgaccttat taaaatgaac ttgtgttttt     4140

ttaacaaaca tgtatgtttt attttgatag tttctttccg taagataatt gaaatattat     4200

actgtaaacc cttttctttt ctttttttga aaagtccaag aatgtactta tacaggcatt     4260

tttccccacc tatttttggc cattctcata ccacagacta aagagtgaaa tgatttgtcc     4320

attgtagctt attgtttatc agtagttctt ttgtcagctg cttacatttt ttctttcatg     4380

gttttgtgaa tcattttcag tatgtaattt ataggaacct tgtcctctgg ttatagtaga     4440

ctgtgtgccc tcctccagtg atggcattat tagacatgct ggtcatttac cctcagaaag     4500

actctcttat tagaatggtg agtgcttcag ttatagtatg tttgaatttt taaaaaattc     4560

tgttttagaa atgtatctta tgctctcatg actatgcagt ttctaaacat acacatagaa     4620

gctgagtctc tgatccaata tgtttttatt tgttccattt aatttatcac atagattggg     4680

aaggcaagct aaaagcctta aaaatgccct ttatattttg agtgatttca gcgttgaaca     4740

ctagtatact atctaaattt gctgctcact ttctttaaac tgtggcaatt aaaggcatgt     4800

ttatacatga cttaatcgtg aaatgtttgt cactcttact gcacagactt atctgcaatc     4860

ataactggtt agtttttttg ttttgttttg ttttattgtt tttaatgaaa ctggtaccat     4920

ctgtgctttc acaaaaaact tccaatgcca tttttgagaa ctaacctaac tagtcatgct     4980

aaccagaaaa tccactgggg aggaggttcc ttttgaaaca aaatgctgtt cagttagtaa     5040

ccaagttact ttgattgcaa aagcagctgt gtttctgata agtactgaac aaatgtgtgt     5100

aattttctgt gccagactta tgactttgtt ttcaagcact gtaatgtggg atggatggtt     5160

agaaacaata atatattagg gtttctgttt aaccctttca ggactgaact gtatctcctt     5220

ttgttaattt tcccctgtgt tgtgataaat gtttgccagc attcagtact gtgttggtcc     5280

agatgtaggt ttatatgctc atttttagct tatttcttgt accttgcagc atgctctacg     5340

cattcagtcc ttaaggggtt tattttacaa actgtgcgcc tgtaaggttt attagcaata     5400

agatagaaaa ttgagcaagt ttataccata attttgtaga aaaaaagaat ctgctcagtt     5460

ccatatttca tccgtgaaaa acttgcaata cgagcagttt caaggaataa ataaaaagga     5520

aatgtaaacc attgtaaaag tcttctgtcg aatgtgcctg atgcatgtat tatcgtcttt     5580

tatttcagaa tacttcataa agataaaatt aaattctata ttatagttgg tgtatttaca     5640

atcttaccat gtacatcaca tcaaagtgat agctctacta atttaatttc cttgtcaatg     5700

tttttaacta tatagtgctt taaagagatt ttttttccct gtgtaaaaaa aaaaaaaaaa     5760

aa                                                                    5762


<210>  1615
<211>  4154
<212>  DNA
<213>  homo sapiens

<400>  1615
ggcgccgcct ccacccgctc cccgctcggt cccgctcgct cgcccaggcc gggctgccct       60

ttcgcgtgtc cgcgctctct tccctccgcc gccgcctcct ccattttgcg agctcgtgtc      120

tgtgacggga gcccgagtca ccgcctgccc gtcggggacg gattctgtgg gtggaaggag      180

acgccgcagc cggagcggcc gaagcagctg ggaccgggac ggggcacgcg cgcccggaac      240

ctcgacccgc ggagcccggc gcggggcgga gggctggctt gtcagctggg caatgggaga      300

ctttcttaaa taggggctct ccccccaccc atggagaaag gggcggctgt ttacttcctt      360

tttttagaaa aaaaaaatat atttccctcc tgctccttct gcgttcacaa gctaagttgt      420

ttatctcggc tgcggcggga actgcggacg gtggcgggcg agcggctcct ctgccagagt      480

tgatattcac tgatggactc caaagaatca ttaactcctg gtagagaaga aaaccccagc      540

agtgtgcttg ctcaggagag gggagatgtg atggacttct ataaaaccct aagaggagga      600

gctactgtga aggtttctgc gtcttcaccc tcactggctg tcgcttctca atcagactcc      660

aagcagcgaa gacttttggt tgattttcca aaaggctcag taagcaatgc gcagcagcca      720

gatctgtcca aagcagtttc actctcaatg ggactgtata tgggagagac agaaacaaaa      780

gtgatgggaa atgacctggg attcccacag cagggccaaa tcagcctttc ctcgggggaa      840

acagacttaa agcttttgga agaaagcatt gcaaacctca ataggtcgac cagtgttcca      900

gagaacccca agagttcagc atccactgct gtgtctgctg cccccacaga gaaggagttt      960

ccaaaaactc actctgatgt atcttcagaa cagcaacatt tgaagggcca gactggcacc     1020

aacggtggca atgtgaaatt gtataccaca gaccaaagca cctttgacat tttgcaggat     1080

ttggagtttt cttctgggtc cccaggtaaa gagacgaatg agagtccttg gagatcagac     1140

ctgttgatag atgaaaactg tttgctttct cctctggcgg gagaagacga ttcattcctt     1200

ttggaaggaa actcgaatga ggactgcaag cctctcattt taccggacac taaacccaaa     1260

attaaggata atggagatct ggttttgtca agccccagta atgtaacact gccccaagtg     1320

aaaacagaaa aagaagattt catcgaactc tgcacccctg gggtaattaa gcaagagaaa     1380

ctgggcacag tttactgtca ggcaagcttt cctggagcaa atataattgg taataaaatg     1440

tctgccattt ctgttcatgg tgtgagtacc tctggaggac agatgtacca ctatgacatg     1500

aatacagcat ccctttctca acagcaggat cagaagccta tttttaatgt cattccacca     1560

attcccgttg gttccgaaaa ttggaatagg tgccaaggat ctggagatga caacttgact     1620

tctctgggga ctctgaactt ccctggtcga acagtttttt ctaatggcta ttcaagcccc     1680

agcatgagac cagatgtaag ctctcctcca tccagctcct caacagcaac aacaggacca     1740

cctcccaaac tctgcctggt gtgctctgat gaagcttcag gatgtcatta tggagtctta     1800

acttgtggaa gctgtaaagt tttcttcaaa agagcagtgg aaggacagca caattaccta     1860

tgtgctggaa ggaatgattg catcatcgat aaaattcgaa gaaaaaactg cccagcatgc     1920

cgctatcgaa aatgtcttca ggctggaatg aacctggaag ctcgaaaaac aaagaaaaaa     1980

ataaaaggaa ttcagcaggc cactacagga gtctcacaag aaacctctga aaatcctggt     2040

aacaaaacaa tagttcctgc aacgttacca caactcaccc ctaccctggt gtcactgttg     2100

gaggttattg aacctgaagt gttatatgca ggatatgata gctctgttcc agactcaact     2160

tggaggatca tgactacgct caacatgtta ggagggcggc aagtgattgc agcagtgaaa     2220

tgggcaaagg caataccagg tttcaggaac ttacacctgg atgaccaaat gaccctactg     2280

cagtactcct ggatgtttct tatggcattt gctctggggt ggagatcata tagacaatca     2340

agtgcaaacc tgctgtgttt tgctcctgat ctgattatta atgagcagag aatgactcta     2400

ccctgcatgt acgaccaatg taaacacatg ctgtatgttt cctctgagtt acacaggctt     2460

caggtatctt atgaagagta tctctgtatg aaaaccttac tgcttctctc ttcagttcct     2520

aaggacggtc tgaagagcca agagctattt gatgaaatta gaatgaccta catcaaagag     2580

ctaggaaaag ccattgtcaa gagggaagga aactccagcc agaactggca gcggttttat     2640

caactgacaa aactcttgga ttctatgcat gaaaatgtta tgtggttaaa accagaaagc     2700

acatctcaca cattaatctg attttcatcc caacaatctt ggcgctcaaa aaatagaact     2760

caatgagaaa aagaagatta tgtgcacttc gttgtcaata ataagtcaac tgatgctcat     2820

cgacaactat aggaggcttt tcattaaatg ggaaaagaag ctgtgccctt ttaggatacg     2880

tgggggaaaa gaaagtcatc ttaattatgt ttaattgtgg atttaagtgc tatatggtgg     2940

tgctgtttga aagcagattt atttcctatg tatgtgttat ctggccatcc caacccaaac     3000

tgttgaagtt tgtagtaact tcagtgagag ttggttactc acaacaaatc ctgaaaagta     3060

tttttagtgt ttgtaggtat tctgtgggat actatacaag cagaactgag gcacttagga     3120

cataacactt ttggggtata tatatccaaa tgcctaaaac tatgggagga aaccttggcc     3180

accccaaaag gaaaactaac atgatttgtg tctatgaagt gctggataat tagcatggga     3240

tgagctctgg gcatgccatg aaggaaagcc acgctccctt cagaattcag aggcagggag     3300

caattccagt ttcacctaag tctcataatt ttagttccct tttaaaaacc ctgaaaacta     3360

catcaccatg gaatgaaaaa tattgttata caatacattg atctgtcaaa cttccagaac     3420

catggtagcc ttcagtgaga tttccatctt ggctggtcac tccctgactg tagctgtagg     3480

tgaatgtgtt tttgtgtgtg tgtgtctggt tttagtgtca gaagggaaat aaaagtgtaa     3540

ggaggacact ttaaaccctt tgggtggagt ttcgtaattt cccagactat tttcaagcaa     3600

cctggtccac ccaggattag tgaccaggtt ttcaggaaag gatttgcttc tctctagaaa     3660

atgtctgaaa ggattttatt ttctgatgaa aggctgtatg aaaataccct cctcaaataa     3720

cttgcttaac tacatataga ttcaagtgtg tcaatattct attttgtata ttaaatgcta     3780

tataatgggg acaaatctat attatactgt gtatggcatt attaagaagc tttttcatta     3840

ttttttatca cagtaatttt aaaatgtgta aaaattaaaa ccagtgactc ctgtttaaaa     3900

ataaaagttg tagtttttta ttcatgctga ataataatct gtagttaaaa aaaaagtgtc     3960

tttttaccta cgcagtgaaa tgtcagactg taaaaccttg tgtggaaatg tttaactttt     4020

attttttcat ttaaatttgc tgttctggta ttaccaaacc acacatttgt accgaattgg     4080

cagtaaatgt tagccattta cagcaatgcc aaatatggag aaacatcata ataaaaaaat     4140

ctgctttttc atta                                                       4154


<210>  1616
<211>  6787
<212>  DNA
<213>  homo sapiens

<400>  1616
ggcgccgcct ccacccgctc cccgctcggt cccgctcgct cgcccaggcc gggctgccct       60

ttcgcgtgtc cgcgctctct tccctccgcc gccgcctcct ccattttgcg agctcgtgtc      120

tgtgacggga gcccgagtca ccgcctgccc gtcggggacg gattctgtgg gtggaaggag      180

acgccgcagc cggagcggcc gaagcagctg ggaccgggac ggggcacgcg cgcccggaac      240

ctcgacccgc ggagcccggc gcggggcgga gggctggctt gtcagctggg caatgggaga      300

ctttcttaaa taggggctct ccccccaccc atggagaaag gggcggctgt ttacttcctt      360

tttttagaaa aaaaaaatat atttccctcc tgctccttct gcgttcacaa gctaagttgt      420

ttatctcggc tgcggcggga actgcggacg gtggcgggcg agcggctcct ctgccagagt      480

tgatattcac tgatggactc caaagaatca ttaactcctg gtagagaaga aaaccccagc      540

agtgtgcttg ctcaggagag gggagatgtg atggacttct ataaaaccct aagaggagga      600

gctactgtga aggtttctgc gtcttcaccc tcactggctg tcgcttctca atcagactcc      660

aagcagcgaa gacttttggt tgattttcca aaaggctcag taagcaatgc gcagcagcca      720

gatctgtcca aagcagtttc actctcaatg ggactgtata tgggagagac agaaacaaaa      780

gtgatgggaa atgacctggg attcccacag cagggccaaa tcagcctttc ctcgggggaa      840

acagacttaa agcttttgga agaaagcatt gcaaacctca ataggtcgac cagtgttcca      900

gagaacccca agagttcagc atccactgct gtgtctgctg cccccacaga gaaggagttt      960

ccaaaaactc actctgatgt atcttcagaa cagcaacatt tgaagggcca gactggcacc     1020

aacggtggca atgtgaaatt gtataccaca gaccaaagca cctttgacat tttgcaggat     1080

ttggagtttt cttctgggtc cccaggtaaa gagacgaatg agagtccttg gagatcagac     1140

ctgttgatag atgaaaactg tttgctttct cctctggcgg gagaagacga ttcattcctt     1200

ttggaaggaa actcgaatga ggactgcaag cctctcattt taccggacac taaacccaaa     1260

attaaggata atggagatct ggttttgtca agccccagta atgtaacact gccccaagtg     1320

aaaacagaaa aagaagattt catcgaactc tgcacccctg gggtaattaa gcaagagaaa     1380

ctgggcacag tttactgtca ggcaagcttt cctggagcaa atataattgg taataaaatg     1440

tctgccattt ctgttcatgg tgtgagtacc tctggaggac agatgtacca ctatgacatg     1500

aatacagcat ccctttctca acagcaggat cagaagccta tttttaatgt cattccacca     1560

attcccgttg gttccgaaaa ttggaatagg tgccaaggat ctggagatga caacttgact     1620

tctctgggga ctctgaactt ccctggtcga acagtttttt ctaatggcta ttcaagcccc     1680

agcatgagac cagatgtaag ctctcctcca tccagctcct caacagcaac aacaggacca     1740

cctcccaaac tctgcctggt gtgctctgat gaagcttcag gatgtcatta tggagtctta     1800

acttgtggaa gctgtaaagt tttcttcaaa agagcagtgg aaggtagaca gcacaattac     1860

ctatgtgctg gaaggaatga ttgcatcatc gataaaattc gaagaaaaaa ctgcccagca     1920

tgccgctatc gaaaatgtct tcaggctgga atgaacctgg aagctcgaaa aacaaagaaa     1980

aaaataaaag gaattcagca ggccactaca ggagtctcac aagaaacctc tgaaaatcct     2040

ggtaacaaaa caatagttcc tgcaacgtta ccacaactca cccctaccct ggtgtcactg     2100

ttggaggtta ttgaacctga agtgttatat gcaggatatg atagctctgt tccagactca     2160

acttggagga tcatgactac gctcaacatg ttaggagggc ggcaagtgat tgcagcagtg     2220

aaatgggcaa aggcaatacc aggtttcagg aacttacacc tggatgacca aatgacccta     2280

ctgcagtact cctggatgtt tcttatggca tttgctctgg ggtggagatc atatagacaa     2340

tcaagtgcaa acctgctgtg ttttgctcct gatctgatta ttaatgagca gagaatgact     2400

ctaccctgca tgtacgacca atgtaaacac atgctgtatg tttcctctga gttacacagg     2460

cttcaggtat cttatgaaga gtatctctgt atgaaaacct tactgcttct ctcttcagtt     2520

cctaaggacg gtctgaagag ccaagagcta tttgatgaaa ttagaatgac ctacatcaaa     2580

gagctaggaa aagccattgt caagagggaa ggaaactcca gccagaactg gcagcggttt     2640

tatcaactga caaaactctt ggattctatg catgaagtgg ttgaaaatct ccttaactat     2700

tgcttccaaa catttttgga taagaccatg agtattgaat tccccgagat gttagctgaa     2760

atcatcacca atcagatacc aaaatattca aatggaaata tcaaaaaact tctgtttcat     2820

caaaagtgac tgccttaata agaatggttg ccttaaagaa agtcgaatta atagctttta     2880

ttgtataaac tatcagtttg tcctgtagag gttttgttgt tttatttttt attgttttca     2940

tctgttgttt tgttttaaat acgcactaca tgtggtttat agagggccaa gacttggcaa     3000

cagaagcagt tgagtcgtca tcacttttca gtgatgggag agtagatggt gaaatttatt     3060

agttaatata tcccagaaat tagaaacctt aatatgtgga cgtaatctcc acagtcaaag     3120

aaggatggca cctaaaccac cagtgcccaa agtctgtgtg atgaactttc tcttcatact     3180

ttttttcaca gttggctgga tgaaattttc tagactttct gttggtgtat cccccccctg     3240

tatagttagg atagcatttt tgatttatgc atggaaacct gaaaaaaagt ttacaagtgt     3300

atatcagaaa agggaagttg tgccttttat agctattact gtctggtttt aacaatttcc     3360

tttatattta gtgaactacg cttgctcatt ttttcttaca taatttttta ttcaagttat     3420

tgtacagctg tttaagatgg gcagctagtt cgtagctttc ccaaataaac tctaaacatt     3480

aatcaatcat ctgtgtgaaa atgggttggt gcttctaacc tgatggcact tagctatcag     3540

aagaccacaa aaattgactc aaatctccag tattcttgtc aaaaaaaaaa aaaaaaaagc     3600

tcatattttg tatatatctg cttcagtgga gaattatata ggttgtgcaa attaacagtc     3660

ctaactggta tagagcacct agtccagtga cctgctgggt aaactgtgga tgatggttgc     3720

aaaagactaa tttaaaaaat aactaccaag aggccctgtc tgtacctaac gccctatttt     3780

tgcaatggct atatggcaag aaagctggta aactatttgt ctttcaggac cttttgaagt     3840

agtttgtata acttcttaaa agttgtgatt ccagataacc agctgtaaca cagctgagag     3900

acttttaatc agacaaagta attcctctca ctaaacttta cccaaaaact aaatctctaa     3960

tatggcaaaa atggctagac acccattttc acattcccat ctgtcaccaa ttggttaatc     4020

tttcctgatg gtacaggaaa gctcagctac tgatttttgt gatttagaac tgtatgtcag     4080

acatccatgt ttgtaaaact acacatccct aatgtgtgcc atagagttta acacaagtcc     4140

tgtgaatttc ttcactgttg aaaattattt taaacaaaat agaagctgta gtagcccttt     4200

ctgtgtgcac cttaccaact ttctgtaaac tcaaaactta acatatttac taagccacaa     4260

gaaatttgat ttctattcaa ggtggccaaa ttatttgtgt aatagaaaac tgaaaatcta     4320

atattaaaaa tatggaactt ctaatatatt tttatattta gttatagttt cagatatata     4380

tcatattggt attcactaat ctgggaaggg aagggctact gcagctttac atgcaattta     4440

ttaaaatgat tgtaaaatag cttgtatagt gtaaaataag aatgattttt agatgagatt     4500

gttttatcat gacatgttat atattttttg taggggtcaa agaaatgctg atggataacc     4560

tatatgattt atagtttgta catgcattca tacaggcagc gatggtctca gaaaccaaac     4620

agtttgctct aggggaagag ggagatggag actggtcctg tgtgcagtga aggttgctga     4680

ggctctgacc cagtgagatt acagaggaag ttatcctctg cctcccattc tgaccaccct     4740

tctcattcca acagtgagtc tgtcagcgca ggtttagttt actcaatctc cccttgcact     4800

aaagtatgta aagtatgtaa acaggagaca ggaaggtggt gcttacatcc ttaaaggcac     4860

catctaatag cgggttactt tcacatacag ccctccccca gcagttgaat gacaacagaa     4920

gcttcagaag tttggcaata gtttgcatag aggtaccagc aatatgtaaa tagtgcagaa     4980

tctcataggt tgccaataat acactaattc ctttctatcc tacaacaaga gtttatttcc     5040

aaataaaatg aggacatgtt tttgttttct ttgaatgctt tttgaatgtt atttgttatt     5100

ttcagtattt tggagaaatt atttaataaa aaaacaatca tttgcttttt gaatgctctc     5160

taaaagggaa tgtaatattt taagatggtg tgtaacccgg ctggataaat ttttggtgcc     5220

taagaaaact gcttgaatat tcttatcaat gacagtgtta agtttcaaaa agagcttcta     5280

aaacgtagat tatcattcct ttatagaatg ttatgtggtt aaaaccagaa agcacatctc     5340

acacattaat ctgattttca tcccaacaat cttggcgctc aaaaaataga actcaatgag     5400

aaaaagaaga ttatgtgcac ttcgttgtca ataataagtc aactgatgct catcgacaac     5460

tataggaggc ttttcattaa atgggaaaag aagctgtgcc cttttaggat acgtggggga     5520

aaagaaagtc atcttaatta tgtttaattg tggatttaag tgctatatgg tggtgctgtt     5580

tgaaagcaga tttatttcct atgtatgtgt tatctggcca tcccaaccca aactgttgaa     5640

gtttgtagta acttcagtga gagttggtta ctcacaacaa atcctgaaaa gtatttttag     5700

tgtttgtagg tattctgtgg gatactatac aagcagaact gaggcactta ggacataaca     5760

cttttggggt atatatatcc aaatgcctaa aactatggga ggaaaccttg gccaccccaa     5820

aaggaaaact aacatgattt gtgtctatga agtgctggat aattagcatg ggatgagctc     5880

tgggcatgcc atgaaggaaa gccacgctcc cttcagaatt cagaggcagg gagcaattcc     5940

agtttcacct aagtctcata attttagttc ccttttaaaa accctgaaaa ctacatcacc     6000

atggaatgaa aaatattgtt atacaataca ttgatctgtc aaacttccag aaccatggta     6060

gccttcagtg agatttccat cttggctggt cactccctga ctgtagctgt aggtgaatgt     6120

gtttttgtgt gtgtgtgtct ggttttagtg tcagaaggga aataaaagtg taaggaggac     6180

actttaaacc ctttgggtgg agtttcgtaa tttcccagac tattttcaag caacctggtc     6240

cacccaggat tagtgaccag gttttcagga aaggatttgc ttctctctag aaaatgtctg     6300

aaaggatttt attttctgat gaaaggctgt atgaaaatac cctcctcaaa taacttgctt     6360

aactacatat agattcaagt gtgtcaatat tctattttgt atattaaatg ctatataatg     6420

gggacaaatc tatattatac tgtgtatggc attattaaga agctttttca ttatttttta     6480

tcacagtaat tttaaaatgt gtaaaaatta aaaccagtga ctcctgttta aaaataaaag     6540

ttgtagtttt ttattcatgc tgaataataa tctgtagtta aaaaaaaagt gtctttttac     6600

ctacgcagtg aaatgtcaga ctgtaaaacc ttgtgtggaa atgtttaact tttatttttt     6660

catttaaatt tgctgttctg gtattaccaa accacacatt tgtaccgaat tggcagtaaa     6720

tgttagccat ttacagcaat gccaaatatg gagaaacatc ataataaaaa aatctgcttt     6780

ttcatta                                                               6787


<210>  1617
<211>  2716
<212>  DNA
<213>  homo sapiens

<400>  1617
ggctcaacga aggaagttca gggcgggacc agagattggc cattccgcta ctgcgcaaag       60

atggtggagg aggagaacat ccgcgtggtt cgttgtggcg gcagcgagtt gaactttagg      120

agagctgtgt tctctgcaga ttctaagtat atcttctgtg tctctggaga ctttgttaaa      180

gtttacagca cagttacaga agagtgtgta cacatactgc atggacacag aaatctggtg      240

actggaatcc agcttaaccc caacaaccat ctacagctgt attcttgttc ccttgatggc      300

acaattaaac tgtgggacta tatagatggc atcttaataa agactttcat agttggatgt      360

aaacttcatg ccctctttac tcttgcccaa gctgaggatt ctgtctttgt tatagtgaat      420

aaagaaaaac cagatatatt tcagctggtt tcagtgaaac tgccaaaatc ctcaagccag      480

gaagtagaag ccaaggagct gtcctttgtt ttggattaca taaaccagtc acccaagtgc      540

attgcctttg gaaacgaggg agtatatgtt gctgcagtac gggaatttta cttgtctgtt      600

tattttttca aaaagaaaac aacatcaagg tttactttat catcatcaag aaataagaag      660

catgctaaaa acaattttac atgtgtagca tgtcacccaa cggaagactg catcgcatct      720

ggtcacatgg atggcaaaat tcgtctttgg aggaattttt atgatgataa gaaatatacg      780

tacacatgtt tacattggca ccatgatatg gttatggatt tggctttttc agtgacaggc      840

accagtctgc tgagtggcgg tcgtgaatct gtacttgtag agtggcgcga tgcaacagag      900

aagaataagg agtttctccc gcgtttagga gctactattg aacatatctc agtctcgcct      960

gcaggagatt tattctgcac ttctcactct gataataaga taataattat tcaccgaaac     1020

cttgaagcat ccgcagtaat tcaaggccta gtgaaagata ggagtatctt cactggtttg     1080

atgattgatc caagaactaa agctttggtt ttgaatggaa aacctggcca cctgcagttt     1140

tattctctcc agagtgataa acagttatac aatttagata ttatacagca agaatatatt     1200

aatgattatg gtctgatcca aattgaacta acaaaggctg catttggctg ctttggtaac     1260

tggcttgcaa cagtggaaca gcggcaagaa aaggaaactg agcttgaatt gcaaatgaaa     1320

ctgtggatgt ataataagaa aacacaaggg tttattctta acactaaaat taacatgcca     1380

cacgaagact gcattacagc tctctgtttc tgtaatgcag aaaaatctga acagcccacc     1440

ttggttacag ctagcaaaga tggttacttc aaagtatgga tattaacaga tgactctgac     1500

atatacaaaa aagctgttgg ctggacctgt gactttgttg gtagttatca caagtatcaa     1560

gcaactaact gttgtttctc cgaagatggt tctttactag cagttagttt tgaggaaata     1620

gtcacaatat gggattctgt aacatgggaa cttaaatgta cattttgcca acgagctggg     1680

aaaataaggc acctttgctt tgggagattg acgtgttcaa agtatctact tggtgctact     1740

gaaaatggca ttctttgctg ttggaatctg ctgagctgtg cattggagtg gaatgcaaaa     1800

ttaaatgtta gagttatgga acccgatcct aattcagaga atattgctgc aatctctcag     1860

tcttcagtgg gttcagactt gtttgtattt aaacctagtg agccaaggcc attgtatatt     1920

caaaagggta tctccagaga gaaagtccag tggggagtgt ttgttccacg agatgtccct     1980

gaatccttca cctcagaagc ttaccagtgg ctaaatagat cccagtttta cttcctaaca     2040

aaatcacaga gtttattgac attcagtaca aagtctccag aagaaaaact cacaccaaca     2100

agcaaacagc tgctagcaga agaaagtctt cccacaaccc cattttattt catattggga     2160

aaacacaggc aacagcagga tgaaaaacta aacgaaactt tagagaatga gctggtacaa     2220

ctacccttaa cagaaaacat acccgcaatt agtgagcttc ttcacactcc agcccatgtc     2280

ctgccatctg ctgctttcct gtgctccatg tttgtaaatt cattgctgct gtctaaagag     2340

actaagagtg ctaaggaaat tcctgaagat gtagatatgg aagaagaaaa agaaagtgaa     2400

gattcagatg aagaaaatga ttttaccgaa aaagtccagg atacaagtaa cacaggttta     2460

ggagaagaca ttatacatca gttgtcaaaa tctgaagaaa aagaactgag aaaatttagg     2520

aaaatagact acagctggat agctgccctt taagccttgg agatggggag gatccttgga     2580

ctttgtgttt ttgattgtat gttgatattc taaaaacatc tattttaatg ttatttctgt     2640

tctaaaaata agataataaa tattaacaaa ctttgctttt ttaaaaaact gataatataa     2700

aaaaaaaaaa aaaaaa                                                     2716


<210>  1618
<211>  3891
<212>  DNA
<213>  homo sapiens

<400>  1618
gagagcgtag tggaggaggc gcggttgtga gtagtaccgg gagtggggtg atcccgggct       60

aggggagcgc ggcggccgcg atcgggctta gtcggagctc cgaagggagt gactaggaca      120

cccgggtggg ctacttttct tccggtgctt ttgctttttt tttcctttgg gctcgggctg      180

agtgtcgccc actgagcaaa gattccctcg taaaacccag agcgaccctc ccgtcaattg      240

ttgggctcgg gagtgtcgcg gtgccccgag cgcgccgggc gcggaggcaa agggagcgga      300

gccggccgcg gacggggccc ggagcttgcc tgcctccctc gctcgcccca gcgggttcgc      360

tcgcgtagag cgcagggcgc gcgcgatgaa ggcggtgagc ccggtgcgcc cctcgggccg      420

caaggcgccg tcgggctgcg gcggcgggga gctggcgctg cgctgcctgg ccgagcacgg      480

ccacagcctg ggtggctccg cagccgcggc ggcggcggcg gcggcagcgc gctgtaaggc      540

ggccgaggcg gcggccgacg agccggcgct gtgcctgcag tgcgatatga acgactgcta      600

tagccgcctg cggaggctgg tgcccaccat cccgcccaac aagaaagtca gcaaagtgga      660

gatcctgcag cacgttatcg actacatcct ggacctgcag ctggcgctgg agacgcaccc      720

ggccctgctg aggcagccac caccgcccgc gccgccacac cacccggccg ggacctgtcc      780

agccgcgccg ccgcggaccc cgctcactgc gctcaacacc gacccggccg gcgcggtgaa      840

caagcagggc gacagcattc tgtgccgctg agccgcgctg tccaggtgtg cggccgcctg      900

agcccgagcc aggagcacta gagagggagg gggaagagca gaagttagag aaaaaaagcc      960

accggaggaa aggaaaaaac atcggccaac ctagaaacgt tttcattcgt cattccaaga     1020

gagagagagg aaagaaaaat acaactttca ttctttcttt gcacgttcat aaacattcta     1080

catacgtatt ctcttttgtc tcttcattta taactgctgt gaattgtaca tttctgtgtt     1140

ttttggaggt gcagttaaac ttttaagctt aagtgtgaca ggactgataa atagaagatc     1200

aagagtagat ccgactttag aagcctactt tgtgaccaag gagctcaatt tttgttttga     1260

agctttacta atctaccaga gcattgtaga tatttttttt ttacatctat tgtttaaaat     1320

agatgattat aacggggcag agaactttct tttctctgca agaatgttac atattgtata     1380

gataaatgag tgacatttca taccatgtat atatagagat gttctataag tgtgagaaag     1440

tatatgcttt aatagatact gtaattataa gatattttta attaaatatt tttttgtaaa     1500

tattatgtgt gtgttttttt ttaatctatg ggaatatttc ttttggaaaa tcatttttca     1560

gctcaattac agagctcttg atatcttgaa tgtcttttct gtttggcctg gctcttaatt     1620

tgcttttgtt ttgcccagta tagactcgga agtaacagtt atagctagtg gtcttgcatg     1680

attgcatgag atgtttaatc acaaattaaa cttgttctga gtccattcaa atgtgttttt     1740

ttaaatgtag attgaaatct ttgtatttga agcatacatg ttgaaaatac accttatcag     1800

tttttaagta cagggtttta tagtgtaata tatacagagt aagtgtttgt ttttgttttt     1860

caactgaggt caaaatggat tctgaatgat tttgcatatg ggatgaggaa atgcttggat     1920

ccttaaggag tttacgaaat ctgctgtttt atcaaagtga aaaaaaattg cttattactc     1980

ttcattttac actaaagctt aatgtcacta agtttcatgt ctgtacagat tatttaaatc     2040

atggaaatga aaaaaatgtt ctctgcttgc taccaaagga caaactcttg gaaatgaaca     2100

ctttctgctt tccttcctcc aaagaattaa taggcaacag tgggagaaaa aaaaggcata     2160

atggcaaatc cttcaagcag ggataaaagt cgatcttcaa acattaactt aagcagacca     2220

aaaattctga tgaccgcatc tagattattt ttttataaaa atgattttca ctatagctat     2280

gttacgctaa gctactgtcc aatctcttgt gatgtgtaac ttttacatgt gaatattaaa     2340

gtagatttct ctgtcttgta ctgtgatttc tggtctcatt tctttaaaac cttactctta     2400

tttttctttt aaggctcttt tttctcctta aggaaggtaa tattttctag gttagatagg     2460

actatcaggg tttgtgaaca ttatgcattt aatgttatgg gtactttaca cacaagttag     2520

atggaatttt tagagtgaaa gaattaagta ggatttaatt gggtgctttg taaatagtca     2580

actgtgtgta taacgtggtc tgtttgattt ttaaaaggaa aggatttgtt tcagattata     2640

caagaataaa agtattatag acccaaggga cttcttatga ggtcaaattc agatatttat     2700

atgaatatga aataccatgg tccctagtag tcagttgaag tggcaatgtc taaacagaaa     2760

tgaacaaaac taatgctagc aggttaaaat caatcaaaat gtttaaaaat tgattctgtc     2820

ctcagcatgt tatttcctca gctctgataa tttactggtc ttgagtattt tgagaatttg     2880

atgttgaacg ttataaagtc aaagaactgc ttgtttagat gaggtttatt tttatttttg     2940

atattattca ttcttgtcac acatcaagaa gaaaacacta gagtgctgct ggaattccaa     3000

atctgaagaa ttctaacgac tgcattcttt gttattaaaa agggcacaat ccttcctttt     3060

tatttggcag tttaatttca gtaggaagca tgtcacatgt gcactgttgg ttagaattat     3120

gcatctgtca tgcctgactg ctgaacccta cctaagcctt ttggcgcagt ttaaaactta     3180

tactggtgga ctgtgaacct caaaacaaat gggtattttt gggttttgag gatagatgtt     3240

actccttaaa gtttgtattt ggggcatgaa aaactactga aagaagaaaa gtgctacaga     3300

tactacattt caaagagttg gcattttccc tttggccact caagcagcat ttgatgtatc     3360

taaagaaaca aagtcattgt ttatttttta aaaaattata tgcagttgta caagatacta     3420

cattccattg aaatgttggc tatgtcctaa ccaggcaacc agataacaaa aacattttga     3480

gtcttttatc taggtagttc taattattca gctacttagt ttaacaaagg aaaatatcct     3540

gacttctctc atttcatttg tagacttttc attgtatagg cacaaccaaa gagtcagact     3600

ggtttaaaac tccagaagga aaaaaagtat cccacacagt ggatgttgtt tctaagaatg     3660

ctacaaaatc ctgacatctc agacatctca atgttaaagg aagaaaaaaa ataccttttc     3720

atttcaaaga actaatatac tttgatattg tgtaaacctt actcaagttt attgtcaagc     3780

tttaactgcc tttttagaac tttttaaaat ttcgagccca caaatctatt gtattagttg     3840

ccttctataa caataaatct tcactgagca aaaggcaaaa aaaaaaaaaa a              3891


<210>  1619
<211>  2996
<212>  DNA
<213>  homo sapiens

<400>  1619
ggctgcaggg cttggcgccc gggcgctttc ggattgggag ggcttcctcc atggaacgcg       60

agcctcgaga cgtctgacgt taggcaccgt tcgcagcgcc tcgggctcgc acggcaggat      120

cgaaagcgtg attggctggc ggcgtctgtg gtctcgggca ccgcccagtc gcgggacgct      180

gcctctgcgg aactgggggt ggggcgtgtt gaccccctta aaggcgccag agcccgcggt      240

cacggctcag gttcccggtg cttcgcgcgt ctgccgttgt cacaggccag ggaggtggca      300

ccaccaggcg aagcttggcg agattgtgtc gtcaagcgcg tacgggcgcc aattggccgg      360

gcgatgtggc gtggactggc gctggcgcga gcgattggct gcgcggcccg ggggcggggc      420

cagtgggcgg tgcgcgccgc agactgtgct caaagcgggc gccatccggg accggcggtt      480

gtctgtggcc ggaggctgat cagtgttcta gaacagatca gacattttgt aatgatgcct      540

gaaataaaca ctaaccacct cgacaagcaa caggttcaac tcctggcaga gatgtgtatc      600

cttattgatg aaaatgacaa taaaattgga gctgagacca agaagaattg tcacctgaac      660

gagaacattg agaaaggatt attgcatcga gcttttagtg tcttcttatt caacaccgaa      720

aataagcttc tgctacagca aagatcagat gctaagatta cctttccagg ttgttttacg      780

aatacgtgtt gtagtcatcc attaagcaat ccagccgagc ttgaggaaag tgacgccctt      840

ggagtgaggc gagcagcaca gagacggctg aaagctgagc taggaattcc cttggaagag      900

gttcctccag aagaaattaa ttatttaaca cgaattcact acaaagctca gtctgatggt      960

atctggggtg aacatgaaat tgattacatt ttgttggtga ggaagaatgt aactttgaat     1020

ccagatccca atgagattaa aagctattgt tatgtgtcaa aggaagaact aaaagaactt     1080

ctgaaaaaag cagccagtgg tgaaattaag ataacgccat ggtttaaaat tattgcagcg     1140

acttttctct ttaaatggtg ggataactta aatcatttga atcagtttgt tgaccatgag     1200

aaaatataca gaatgtgaat atgtaggtaa atgattacag aaaaatttat ctgcttaaca     1260

aacttagaat gactttttcc ttttaaattt agttctatca ttaatttatc attaaattta     1320

gttctatcat ttggtactat cattaatgta ttatatacac tgatacttta aaacttgtgt     1380

ggaaaaaact aacttataat tttgtatcac acaccctgga tatgtgttct gtttctaagc     1440

gacatttgtg agagattatt gtaaaatgag agcgagcaaa taaaacttaa tttaatcttt     1500

gcagatacat acttatggga aatttgaaca aatgagtgaa actctgtttt tagtaggctg     1560

tgataaacat ttccggagca cttgcagagg acttgctatt tgccaggtgc tttatgtatc     1620

attaaatttt tctcatagtt cagaaaaatg tgcaaaggaa actattgtct cgctccttca     1680

aaacagtctt aattaacttt catattagca gattaaacta gcagagcagg ttcaagggaa     1740

attaaatgat atggacccta atttgtatca ttctgagttg attgtgtggt ttattcattc     1800

tggaaacatg ttgatactta cagtcagcca ctgcttttga taagtgatat tgattaggtt     1860

gaatcttctt gtaaatagta tttaccagtt agcaaagtct gtgttttcag aattacagtg     1920

agcacagagg tgttcataaa atgggaattg agtcccactc ggtaagagtt gcttaaactt     1980

gacactgttg acatttgggc tggataaaac ccctgtggtg gggtctgtgc tgtgcattgc     2040

aggatggtga gcagcgtccc tctcatgtga cacccacagt tatgccggat gttgccagat     2100

gcccctaggg gacagagtca acccccaact gaggaccact gtcctacaga gtcaggaaat     2160

attgtaggga gaaaaaaata acaacaacaa aggcctgtgt taatgttaaa tagatgagat     2220

tatggaatgt gtatattaat gttaaaaatt gtaccttgat caatgtactt tttataaact     2280

tgccatagat atctcagatt tgaaacctca agacagattt attattctta aatgctgtat     2340

gataatgaag aaaaataaaa atttatttct tgcaaagtta aatgtttgtt aaattcaata     2400

gaatgactca tttatggtta actttgggca atttataatt tcagacaaga ctgtttagca     2460

agtattttat tgaaaagtaa aaaaaattgc aatttaatac tgtgtttagt ttgttaaaat     2520

tttgatacac taataggata ttgcctgtat agtttccgtt gcatttataa tattgtttct     2580

aattttttta gttttatttt ctaggaagtt ttaggctgaa agccacatat aattagttat     2640

gtgataacta tgagttgcca tggctactga attggacatg ggacccttag actgctaccc     2700

agcaccttgt taagtactta gcaagagtta gatactactg ttgtaatatt actaggatgc     2760

catccagaaa atgtaaggaa tgtcttttga cctgataaac tccttagaac tccttcatct     2820

tttataaaga ggagtatccc tctcctagat atagctgctt ctgaccccaa aggcagatgt     2880

gttggttttc aactagaaag ctaaatggta cctataaatt ttttttttct taaactgttt     2940

taaactctta atcttcaaaa tatatacttc tttgattctg gtcaaaaaaa aaaaaa         2996


<210>  1620
<211>  4978
<212>  DNA
<213>  homo sapiens

<400>  1620
ggtttccgga gctgcggcgg cgcagactgg gagggggagc cgggggttcc gacgtcgcag       60

ccgagggaac aagccccaac cggatcctgg acaggcaccc cggcttggcg ctgtctctcc      120

ccctcggctc ggagaggccc ttcggcctga gggagcctcg ccgcccgtcc ccggcacacg      180

cgcagccccg gcctctcggc ctctgccgga gaaacagttg ggacccctga ttttagcagg      240

atggcccaat ggaatcagct acagcagctt gacacacggt acctggagca gctccatcag      300

ctctacagtg acagcttccc aatggagctg cggcagtttc tggccccttg gattgagagt      360

caagattggg catatgcggc cagcaaagaa tcacatgcca ctttggtgtt tcataatctc      420

ctgggagaga ttgaccagca gtatagccgc ttcctgcaag agtcgaatgt tctctatcag      480

cacaatctac gaagaatcaa gcagtttctt cagagcaggt atcttgagaa gccaatggag      540

attgcccgga ttgtggcccg gtgcctgtgg gaagaatcac gccttctaca gactgcagcc      600

actgcggccc agcaaggggg ccaggccaac caccccacag cagccgtggt gacggagaag      660

cagcagatgc tggagcagca ccttcaggat gtccggaaga gagtgcagga tctagaacag      720

aaaatgaaag tggtagagaa tctccaggat gactttgatt tcaactataa aaccctcaag      780

agtcaaggag acatgcaaga tctgaatgga aacaaccagt cagtgaccag gcagaagatg      840

cagcagctgg aacagatgct cactgcgctg gaccagatgc ggagaagcat cgtgagtgag      900

ctggcggggc ttttgtcagc gatggagtac gtgcagaaaa ctctcacgga cgaggagctg      960

gctgactgga agaggcggca acagattgcc tgcattggag gcccgcccaa catctgccta     1020

gatcggctag aaaactggat aacgtcatta gcagaatctc aacttcagac ccgtcaacaa     1080

attaagaaac tggaggagtt gcagcaaaaa gtttcctaca aaggggaccc cattgtacag     1140

caccggccga tgctggagga gagaatcgtg gagctgttta gaaacttaat gaaaagtgcc     1200

tttgtggtgg agcggcagcc ctgcatgccc atgcatcctg accggcccct cgtcatcaag     1260

accggcgtcc agttcactac taaagtcagg ttgctggtca aattccctga gttgaattat     1320

cagcttaaaa ttaaagtgtg cattgacaaa gactctgggg acgttgcagc tctcagagga     1380

tcccggaaat ttaacattct gggcacaaac acaaaagtga tgaacatgga agaatccaac     1440

aacggcagcc tctctgcaga attcaaacac ttgaccctga gggagcagag atgtgggaat     1500

gggggccgag ccaattgtga tgcttccctg attgtgactg aggagctgca cctgatcacc     1560

tttgagaccg aggtgtatca ccaaggcctc aagattgacc tagagaccca ctccttgcca     1620

gttgtggtga tctccaacat ctgtcagatg ccaaatgcct gggcgtccat cctgtggtac     1680

aacatgctga ccaacaatcc caagaatgta aactttttta ccaagccccc aattggaacc     1740

tgggatcaag tggccgaggt cctgagctgg cagttctcct ccaccaccaa gcgaggactg     1800

agcatcgagc agctgactac actggcagag aaactcttgg gacctggtgt gaattattca     1860

gggtgtcaga tcacatgggc taaattttgc aaagaaaaca tggctggcaa gggcttctcc     1920

ttctgggtct ggctggacaa tatcattgac cttgtgaaaa agtacatcct ggccctttgg     1980

aacgaagggt acatcatggg ctttatcagt aaggagcggg agcgggccat cttgagcact     2040

aagcctccag gcaccttcct gctaagattc agtgaaagca gcaaagaagg aggcgtcact     2100

ttcacttggg tggagaagga catcagcggt aagacccaga tccagtccgt ggaaccatac     2160

acaaagcagc agctgaacaa catgtcattt gctgaaatca tcatgggcta taagatcatg     2220

gatgctacca atatcctggt gtctccactg gtctatctct atcctgacat tcccaaggag     2280

gaggcattcg gaaagtattg tcggccagag agccaggagc atcctgaagc tgacccaggt     2340

agcgctgccc catacctgaa gaccaagttt atctgtgtga caccaacgac ctgcagcaat     2400

accattgacc tgccgatgtc cccccgcact ttagattcat tgatgcagtt tggaaataat     2460

ggtgaaggtg ctgaaccctc agcaggaggg cagtttgagt ccctcacctt tgacatggag     2520

ttgacctcgg agtgcgctac ctcccccatg tgaggagctg agaacggaag ctgcagaaag     2580

atacgactga ggcgcctacc tgcattctgc cacccctcac acagccaaac cccagatcat     2640

ctgaaactac taactttgtg gttccagatt ttttttaatc tcctacttct gctatctttg     2700

agcaatctgg gcacttttaa aaatagagaa atgagtgaat gtgggtgatc tgcttttatc     2760

taaatgcaaa taaggatgtg ttctctgaga cccatgatca ggggatgtgg cggggggtgg     2820

ctagagggag aaaaaggaaa tgtcttgtgt tgttttgttc ccctgccctc ctttctcagc     2880

agctttttgt tattgttgtt gttgttctta gacaagtgcc tcctggtgcc tgcggcatcc     2940

ttctgcctgt ttctgtaagc aaatgccaca ggccacctat agctacatac tcctggcatt     3000

gcacttttta accttgctga catccaaata gaagatagga ctatctaagc cctaggtttc     3060

tttttaaatt aagaaataat aacaattaaa gggcaaaaaa cactgtatca gcatagcctt     3120

tctgtattta agaaacttaa gcagccgggc atggtggctc acgcctgtaa tcccagcact     3180

ttgggaggcc gaggcggatc ataaggtcag gagatcaaga ccatcctggc taacacggtg     3240

aaaccccgtc tctactaaaa gtacaaaaaa ttagctgggt gtggtggtgg gcgcctgtag     3300

tcccagctac tcgggaggct gaggcaggag aatcgcttga acctgagagg cggaggttgc     3360

agtgagccaa aattgcacca ctgcacactg cactccatcc tgggcgacag tctgagactc     3420

tgtctcaaaa aaaaaaaaaa aaaaaagaaa cttcagttaa cagcctcctt ggtgctttaa     3480

gcattcagct tccttcaggc tggtaattta tataatccct gaaacgggct tcaggtcaaa     3540

cccttaagac atctgaagct gcaacctggc ctttggtgtt gaaataggaa ggtttaagga     3600

gaatctaagc attttagact tttttttata aatagactta ttttcctttg taatgtattg     3660

gccttttagt gagtaaggct gggcagaggg tgcttacaac cttgactccc tttctccctg     3720

gacttgatct gctgtttcag aggctaggtt gtttctgtgg gtgccttatc agggctggga     3780

tacttctgat tctggcttcc ttcctgcccc accctcccga ccccagtccc cctgatcctg     3840

ctagaggcat gtctccttgc gtgtctaaag gtccctcatc ctgtttgttt taggaatcct     3900

ggtctcagga cctcatggaa gaagaggggg agagagttac aggttggaca tgatgcacac     3960

tatggggccc cagcgacgtg tctggttgag ctcagggaat atggttctta gccagtttct     4020

tggtgatatc cagtggcact tgtaatggcg tcttcattca gttcatgcag ggcaaaggct     4080

tactgataaa cttgagtctg ccctcgtatg agggtgtata cctggcctcc ctctgaggct     4140

ggtgactcct ccctgctggg gccccacagg tgaggcagaa cagctagagg gcctccccgc     4200

ctgcccgcct tggctggcta gctcgcctct cctgtgcgta tgggaacacc tagcacgtgc     4260

tggatgggct gcctctgact cagaggcatg gccggatttg gcaactcaaa accaccttgc     4320

ctcagctgat cagagtttct gtggaattct gtttgttaaa tcaaattagc tggtctctga     4380

attaaggggg agacgacctt ctctaagatg aacagggttc gccccagtcc tcctgcctgg     4440

agacagttga tgtgtcatgc agagctctta cttctccagc aacactcttc agtacataat     4500

aagcttaact gataaacaga atatttagaa aggtgagact tgggcttacc attgggttta     4560

aatcataggg acctagggcg agggttcagg gcttctctgg agcagatatt gtcaagttca     4620

tggccttagg tagcatgtat ctggtcttaa ctctgattgt agcaaaagtt ctgagaggag     4680

ctgagccctg ttgtggccca ttaaagaaca gggtcctcag gccctgcccg cttcctgtcc     4740

actgccccct ccccatcccc agcccagccg agggaatccc gtgggttgct tacctaccta     4800

taaggtggtt tataagctgc tgtcctggcc actgcattca aattccaatg tgtacttcat     4860

agtgtaaaaa tttatattat tgtgaggttt tttgtctttt tttttttttt ttttttttgg     4920

tatattgctg tatctacttt aacttccaga aataaacgtt atataggaac cgtaaaaa       4978


<210>  1621
<211>  4819
<212>  DNA
<213>  homo sapiens

<400>  1621
cgctgtctct ccccctcggc tcggagaggc ccttcggcct gagggagcct cgccgcccgt       60

ccccggcaca cgcgcagccc cggcctctcg gcctctgccg gagaaacagt tgggacccct      120

gattttagca ggatggccca atggaatcag ctacagcagc ttgacacacg gtacctggag      180

cagctccatc agctctacag tgacagcttc ccaatggagc tgcggcagtt tctggcccct      240

tggattgaga gtcaagattg ggcatatgcg gccagcaaag aatcacatgc cactttggtg      300

tttcataatc tcctgggaga gattgaccag cagtatagcc gcttcctgca agagtcgaat      360

gttctctatc agcacaatct acgaagaatc aagcagtttc ttcagagcag gtatcttgag      420

aagccaatgg agattgcccg gattgtggcc cggtgcctgt gggaagaatc acgccttcta      480

cagactgcag ccactgcggc ccagcaaggg ggccaggcca accaccccac agcagccgtg      540

gtgacggaga agcagcagat gctggagcag caccttcagg atgtccggaa gagagtgcag      600

gatctagaac agaaaatgaa agtggtagag aatctccagg atgactttga tttcaactat      660

aaaaccctca agagtcaagg agacatgcaa gatctgaatg gaaacaacca gtcagtgacc      720

aggcagaaga tgcagcagct ggaacagatg ctcactgcgc tggaccagat gcggagaagc      780

atcgtgagtg agctggcggg gcttttgtca gcgatggagt acgtgcagaa aactctcacg      840

gacgaggagc tggctgactg gaagaggcgg caacagattg cctgcattgg aggcccgccc      900

aacatctgcc tagatcggct agaaaactgg ataacgtcat tagcagaatc tcaacttcag      960

acccgtcaac aaattaagaa actggaggag ttgcagcaaa aagtttccta caaaggggac     1020

cccattgtac agcaccggcc gatgctggag gagagaatcg tggagctgtt tagaaactta     1080

atgaaaagtg cctttgtggt ggagcggcag ccctgcatgc ccatgcatcc tgaccggccc     1140

ctcgtcatca agaccggcgt ccagttcact actaaagtca ggttgctggt caaattccct     1200

gagttgaatt atcagcttaa aattaaagtg tgcattgaca aagactctgg ggacgttgca     1260

gctctcagag gatcccggaa atttaacatt ctgggcacaa acacaaaagt gatgaacatg     1320

gaagaatcca acaacggcag cctctctgca gaattcaaac acttgaccct gagggagcag     1380

agatgtggga atgggggccg agccaattgt gatgcttccc tgattgtgac tgaggagctg     1440

cacctgatca cctttgagac cgaggtgtat caccaaggcc tcaagattga cctagagacc     1500

cactccttgc cagttgtggt gatctccaac atctgtcaga tgccaaatgc ctgggcgtcc     1560

atcctgtggt acaacatgct gaccaacaat cccaagaatg taaacttttt taccaagccc     1620

ccaattggaa cctgggatca agtggccgag gtcctgagct ggcagttctc ctccaccacc     1680

aagcgaggac tgagcatcga gcagctgact acactggcag agaaactctt gggacctggt     1740

gtgaattatt cagggtgtca gatcacatgg gctaaatttt gcaaagaaaa catggctggc     1800

aagggcttct ccttctgggt ctggctggac aatatcattg accttgtgaa aaagtacatc     1860

ctggcccttt ggaacgaagg gtacatcatg ggctttatca gtaaggagcg ggagcgggcc     1920

atcttgagca ctaagcctcc aggcaccttc ctgctaagat tcagtgaaag cagcaaagaa     1980

ggaggcgtca ctttcacttg ggtggagaag gacatcagcg gtaagaccca gatccagtcc     2040

gtggaaccat acacaaagca gcagctgaac aacatgtcat ttgctgaaat catcatgggc     2100

tataagatca tggatgctac caatatcctg gtgtctccac tggtctatct ctatcctgac     2160

attcccaagg aggaggcatt cggaaagtat tgtcggccag agagccagga gcatcctgaa     2220

gctgacccag gtagcgctgc cccatacctg aagaccaagt ttatctgtgt gacaccattc     2280

attgatgcag tttggaaata atggtgaagg tgctgaaccc tcagcaggag ggcagtttga     2340

gtccctcacc tttgacatgg agttgacctc ggagtgcgct acctccccca tgtgaggagc     2400

tgagaacgga agctgcagaa agatacgact gaggcgccta cctgcattct gccacccctc     2460

acacagccaa accccagatc atctgaaact actaactttg tggttccaga ttttttttaa     2520

tctcctactt ctgctatctt tgagcaatct gggcactttt aaaaatagag aaatgagtga     2580

atgtgggtga tctgctttta tctaaatgca aataaggatg tgttctctga gacccatgat     2640

caggggatgt ggcggggggt ggctagaggg agaaaaagga aatgtcttgt gttgttttgt     2700

tcccctgccc tcctttctca gcagcttttt gttattgttg ttgttgttct tagacaagtg     2760

cctcctggtg cctgcggcat ccttctgcct gtttctgtaa gcaaatgcca caggccacct     2820

atagctacat actcctggca ttgcactttt taaccttgct gacatccaaa tagaagatag     2880

gactatctaa gccctaggtt tctttttaaa ttaagaaata ataacaatta aagggcaaaa     2940

aacactgtat cagcatagcc tttctgtatt taagaaactt aagcagccgg gcatggtggc     3000

tcacgcctgt aatcccagca ctttgggagg ccgaggcgga tcataaggtc aggagatcaa     3060

gaccatcctg gctaacacgg tgaaaccccg tctctactaa aagtacaaaa aattagctgg     3120

gtgtggtggt gggcgcctgt agtcccagct actcgggagg ctgaggcagg agaatcgctt     3180

gaacctgaga ggcggaggtt gcagtgagcc aaaattgcac cactgcacac tgcactccat     3240

cctgggcgac agtctgagac tctgtctcaa aaaaaaaaaa aaaaaaaaga aacttcagtt     3300

aacagcctcc ttggtgcttt aagcattcag cttccttcag gctggtaatt tatataatcc     3360

ctgaaacggg cttcaggtca aacccttaag acatctgaag ctgcaacctg gcctttggtg     3420

ttgaaatagg aaggtttaag gagaatctaa gcattttaga ctttttttta taaatagact     3480

tattttcctt tgtaatgtat tggcctttta gtgagtaagg ctgggcagag ggtgcttaca     3540

accttgactc cctttctccc tggacttgat ctgctgtttc agaggctagg ttgtttctgt     3600

gggtgcctta tcagggctgg gatacttctg attctggctt ccttcctgcc ccaccctccc     3660

gaccccagtc cccctgatcc tgctagaggc atgtctcctt gcgtgtctaa aggtccctca     3720

tcctgtttgt tttaggaatc ctggtctcag gacctcatgg aagaagaggg ggagagagtt     3780

acaggttgga catgatgcac actatggggc cccagcgacg tgtctggttg agctcaggga     3840

atatggttct tagccagttt cttggtgata tccagtggca cttgtaatgg cgtcttcatt     3900

cagttcatgc agggcaaagg cttactgata aacttgagtc tgccctcgta tgagggtgta     3960

tacctggcct ccctctgagg ctggtgactc ctccctgctg gggccccaca ggtgaggcag     4020

aacagctaga gggcctcccc gcctgcccgc cttggctggc tagctcgcct ctcctgtgcg     4080

tatgggaaca cctagcacgt gctggatggg ctgcctctga ctcagaggca tggccggatt     4140

tggcaactca aaaccacctt gcctcagctg atcagagttt ctgtggaatt ctgtttgtta     4200

aatcaaatta gctggtctct gaattaaggg ggagacgacc ttctctaaga tgaacagggt     4260

tcgccccagt cctcctgcct ggagacagtt gatgtgtcat gcagagctct tacttctcca     4320

gcaacactct tcagtacata ataagcttaa ctgataaaca gaatatttag aaaggtgaga     4380

cttgggctta ccattgggtt taaatcatag ggacctaggg cgagggttca gggcttctct     4440

ggagcagata ttgtcaagtt catggcctta ggtagcatgt atctggtctt aactctgatt     4500

gtagcaaaag ttctgagagg agctgagccc tgttgtggcc cattaaagaa cagggtcctc     4560

aggccctgcc cgcttcctgt ccactgcccc ctccccatcc ccagcccagc cgagggaatc     4620

ccgtgggttg cttacctacc tataaggtgg tttataagct gctgtcctgg ccactgcatt     4680

caaattccaa tgtgtacttc atagtgtaaa aatttatatt attgtgaggt tttttgtctt     4740

tttttttttt tttttttttt ggtatattgc tgtatctact ttaacttcca gaaataaacg     4800

ttatatagga accgtaaaa                                                  4819


<210>  1622
<211>  7988
<212>  DNA
<213>  homo sapiens

<400>  1622
ctcctcctcc tgctttcctc cagtaagtgc atacccgcta gtggtctgta caggcggcac       60

ggtttgatgg cagagatatt ttctttccaa actgttcaaa atgatgaacg aagatgcagc      120

tcagaaaagc gacagtggag agaagttcaa cggcagtagt cagaggagaa aaagacccaa      180

gaagtctgac agcaatgcaa gcttcctccg tgctgccaga gcaggcaacc tggacaaagt      240

tgtggaatat ctgaaggggg gcatagacat caatacctgc aatcagaatg gactcaacgc      300

tctccatctg gctgccaagg aaggccacgt ggggctggtg caggagctgc tgggaagagg      360

gtcctctgtg gattctgcca ctaagaaggg aaataccgct cttcacattg catctttggc      420

tggacaagca gaagttgtca aagttcttgt taaggaagga gccaatatta atgcacagtc      480

tcagaatggc tttactcctt tatacatggc tgcccaagag aatcacattg atgttgtaaa      540

atatttgctg gaaaatggag ctaatcagag cactgctaca gaggatggct ttactcctct      600

agctgtggca ctccagcaag gacacaacca ggcggtggcc atcctcttgg agaatgacac      660

caaagggaaa gtgaggctgc cagctctgca tattgccgct aggaaagacg acaccaaatc      720

tgccgcactt ctgcttcaga atgaccacaa tgctgacgta caatccaaga tgatggtgaa      780

taggacaact gagagtggtt ttaccccttt gcacatagct gcacattacg gaaatgtcaa      840

cgtggcaact cttcttctaa accggggagc tgctgtggac ttcacagcca ggaatggaat      900

cactcctctg catgtggctt ccaaaagagg aaatacaaac atggtgaagc tcttactgga      960

tcgaggcggt cagatcgatg ccaaaactag ggatgggttg acaccacttc actgtgctgc     1020

acgaagtggg catgaccaag tggtggaact tctgttggaa cggggtgccc ccttgctggc     1080

aaggactaag aatgggctgt ctccactaca catggctgcc cagggagacc acgtggaatg     1140

tgtgaagcac ctgttacagc acaaggcacc tgttgatgat gtcaccctag actacctgac     1200

agccctccac gttgctgcgc actgtggcca ctaccgtgta accaaactcc ttttagacaa     1260

gagagccaat ccgaacgcca gagccctgaa tggttttact ccactgcaca ttgcctgcaa     1320

gaaaaaccgc atcaaagtca tggaactgct ggtgaaatat ggggcttcaa tccaagctat     1380

aacagagtct ggcctcacac caatacatgt ggctgccttc atgggccact tgaacattgt     1440

cctccttctg ctgcagaacg gagcctctcc agatgtcact aacattcgtg gtgagacggc     1500

actacacatg gcagcccgag ccgggcaggt ggaagtggtc cgatgcctcc tgagaaatgg     1560

tgcccttgtt gatgccagag ccagggagga acagacacct ttacatattg cctcccgcct     1620

gggtaagaca gaaattgtcc agctgcttct acaacatatg gctcatccag atgcggccac     1680

tacaaatggg tacacaccac tgcacatctc tgcccgggag ggccaggtgg atgtggcatc     1740

agtcctattg gaagcaggag cagcccactc cttagctacc aagaagggtt ttactcccct     1800

gcatgtagca gccaagtatg gaagcctgga tgtggcaaaa cttctcttgc aacgccgtgc     1860

tgccgcagat tctgcaggga agaacggcct taccccgctc catgttgctg ctcattatga     1920

caaccagaag gtggcgctgc tgttactgga gaagggtgct tcccctcatg ccactgccaa     1980

gaatggctat actccgttac atattgctgc caagaagaat caaatgcaga tagcttccac     2040

actcctgaac tatggagcag agacaaacat tgtgacaaag caaggagtaa ctccactcca     2100

tctggcctcg caggaggggc acacagatat ggttaccttg cttctggata agggagccaa     2160

tatccacatg tcaactaaga gtggactcac atccttacac cttgcagccc aggaagataa     2220

agtgaatgtt gctgatattc tcaccaagca tggagctgat caggatgctc atacaaagct     2280

tggttacaca cctttaattg tggcctgtca ctatggaaat gtgaaaatgg tcaactttct     2340

tctgaagcag ggagcaaatg ttaacgcaaa aaccaagaac ggctacacgc ctttgcacca     2400

ggccgctcag cagggtcaca cgcacatcat caacgtcctg ctccagcatg gggccaagcc     2460

caacgccacc actgcgaatg gcaacactgc cttggcgatt gctaagcgtc tgggctacat     2520

ctccgtggtc gacaccctga aggttgtgac tgaggaggtc accaccacca ccacaactat     2580

tacagaaaaa cacaaactaa atgtacctga gacgatgact gaggttcttg atgtttctga     2640

tgaagagggt gatgacacaa tgactggtga tgggggagaa taccttaggc ctgaggacct     2700

aaaagaactg ggtgatgact cactacccag cagtcagttc ctggatggta tgaattacct     2760

gcgatacagc ttggagggag gacgatctga cagccttcga tccttcagtt ccgacaggtc     2820

tcacactctg agccatgcct cctacctgag ggacagtgcc gtgatggatg actcagttgt     2880

gattcccagt caccaggtgt caactctagc caaggaggca gaaaggaatt cttatcgcct     2940

aagctggggc actgagaact tagacaacgt ggctctttct tctagtccta ttcattcagg     3000

tttcctggtt agttttatgg tggatgcccg aggtggtgct atgcgaggat gcagacacaa     3060

tgggctccga atcattattc cacctcggaa atgtactgct ccaacgcgag tcacctgccg     3120

actggtcaag cgccacagac tggcaacaat gcctccaatg gtggaaggag aaggcctggc     3180

cagtcgcctg atcgaagttg gaccttctgg tgctcagttc cttggtaaac ttcacctgcc     3240

aacggctcct cccccactta atgagggaga aagtttggtc agccgcattc ttcagctggg     3300

gcctcctgga accaaattcc ttgggcctgt gatcgtggag atccctcact ttgcggccct     3360

tcgaggaaag gaaagggaac tggtggtcct gcgcagtgag aatggggaca gctggaaaga     3420

gcatttctgt gactacactg aagatgaatt gaatgaaatt cttaacggca tggatgaagt     3480

actggatagc ccagaagacc tagaaaagaa acgaatctgc cgcatcatca cccgagactt     3540

cccacagtac tttgcagtgg tgtctcgtat caaacaggac agcaatctga ttggcccaga     3600

aggaggtgta ctgagcagca cagtggtgcc ccaggtgcag gccgtcttcc cagagggggc     3660

actcaccaag cggatccgcg taggcctgca ggctcaacct atgcacagtg agctggttaa     3720

gaagatccta ggcaacaaag ctaccttcag ccctatagtc actttggaac ctagaagaag     3780

aaaattccac aaaccaatta ccatgaccat tcctgtcccc aaagcttcaa gtgatgtcat     3840

gttgaatggt tttgggggag atgcaccaac cttaagatta ctatgcagca taacaggtgg     3900

aaccacccct gcccagtggg aagatattac aggaactacg ccattaacat ttgtcaatga     3960

atgtgtttcc tttacaacaa acgtgtctgc caggttctgg ctgatagatt gtcgacagat     4020

ccaggaatcc gttacttttg catcacaagt atacagagaa attatctgcg taccttatat     4080

ggccaaattt gtagtgtttg ccaaatcaca tgaccccatt gaagccaggt tgaggtgttt     4140

ctgcatgact gatgataaag tggataagac ccttgaacaa caagaaaatt ttgctgaggt     4200

ggccagaagc agggatgtgg aggtgttaga aggaaaaccc atctacgttg attgtttcgg     4260

caacttggta ccattaacta aaagtggcca gcatcatata ttcagttttt ttgccttcaa     4320

agaaaataga cttcctctat ttgtcaaggt acgcgatacg actcaggaac cttgcggacg     4380

actatcattt atgaaggagc caaaatccac gagaggcctg gtgcatcaag ctatttgcaa     4440

cttaaacatc actttgccga tttatacaaa ggaatcagag tcagatcaag aacaggagga     4500

agagatcgat atgacatcag aaaaaaatcc acaggatgag caggaacgga tcgaggaaag     4560

gctggcttat attgctgatc accttggctt cagctggaca gaattagcaa gagaactgga     4620

tttcactgag gagcaaattc atcaaattcg aattgaaaat cccaactctc ttcaagacca     4680

gagtcatgca ctgttgaagt actggctaga gagggatggg aaacatgcta cagataccaa     4740

cctcgttgaa tgtctcacca agatcaaccg aatggatatt gttcatctca tggagaccaa     4800

cacagaacct ctccaggagc gcatcagtca tagttatgca gaaattgaac agaccattac     4860

actggatcat agtgaagggt tctcggtact tcaagaggag ttatgcactg cacagcacaa     4920

gcagaaagag gagcaagctg tttctaaaga aagtgagacc tgcgatcacc ctcctatcgt     4980

ctcagaggaa gacatttctg ttggttattc cacttttcag gatggcgtcc ccaaaactga     5040

gggggacagc tcagcaacag cactctttcc ccaaactcac aaggagcaag ttcaacagga     5100

tttctcaggg aaaatgcaag acctgcctga agagtcatct ctggaatatc agcaggaata     5160

ttttgtgaca actccaggaa cagaaacatc agagactcag aaggctatga tagtacccag     5220

ctctcccagc aagacacctg aggaagttag cacccctgca gaggaggaga agctgtacct     5280

ccagacccca acatccagcg agcggggagg ctctcccatc atacaagaac ccgaagagcc     5340

ctcagagcac agagaggaga gctctccgcg gaaaaccagc ctcgtaatag tggagtctgc     5400

cgataaccag cctgagacct gtgaaagact cgatgaagat gcagcttttg aaaagggaga     5460

cgatatgcct gaaatacccc cagaaacagt cacagaagaa gaatacattg atgagcatgg     5520

acacaccgtg gtaaagaagg ttactaggaa aatcattagg cggtatgtat cctctgaagg     5580

cacagagaaa gaagagatta tggtgcaggg aatgccacag gaacctgtca acatcgagga     5640

aggggatggc tattccaaag ttataaagcg tgttgtattg aagagtgaca ccgagcagtc     5700

agaggacaac aatgagtaaa gccatcacac agaagagggc tgtggtgaag gaccagcatg     5760

gaaaacgcat tgacttggag cacctggagg atgtaccaga agcactagac caggacgacc     5820

tccagcgcga tctccagcag ctccttcggc atttctgcaa ggaggacttg aagcaagagg     5880

ccaagtgagg ggctgcccag ttctcacacc agaaaccaca cattcactca atatgcagct     5940

tcctgtttca gtaggggagt gacctaactg gcctaattaa tgggataccc cgacatttcc     6000

actgttagca aatatacggc attttgcttt agttttcccc catcctcttt aactataaag     6060

ctaatttgtg accaaagatg gcatccttca tactggatgc tgtatccaat actttgttgt     6120

gtctgtgcta acctgggaac tggccacctc cattgttctt tgcttctgca caagatccat     6180

gaaaatccat tgatcagaag aacttcacct gcagacctct tcaagtgaca ctatgtagga     6240

atccttccaa ggaatatcta tgtacaatgt atatagctga aatgctcaga tgaacaacat     6300

attaaaatta aaaccactgc ctattgtaac tacactgggc atcagaataa aaggcctcta     6360

gaaattgctg aacaatggtt aattaagata ttgctaacac aatcgagtga taatacagtt     6420

ttactgcaaa agaagcactt caaacctatt atgtccttag aacttccaga gtagccactg     6480

ctcccagtta aaggtgggtc agtagccttg cagaactgtc ctgagaagtt attgctggtg     6540

ctggccagcc atggcttagg actccaacag ccactctgag ggaggggaga agggagcaga     6600

ggccacgcag aatgaaccga tggggtattc agttgctggc agctacattg tgtggcattc     6660

tagcatcttc aggtctttag atcttggaca agttggcagg gtattttaaa agctataact     6720

actgtagttt tccagttttc attgctgctt tagcaaacca cgctgtctta cagtggtact     6780

ttcttctggc cactgcactg tagataattc attggaaaca agatttaccc actacataaa     6840

aggttaaact ccttcagtat gttggagtgg tttctttttt tttttctttc tttctttttt     6900

ttcttcaggt ttatatcttc tctaatacct gcatgtggcg tttaaaaatc aagaccacgg     6960

tcaaacccct cttctaatca cattaattgt ttccattctt tttaccctga gtgagcactt     7020

ttcactttcc agctaggtct gtttttcagc ttgcagacaa gattgagaaa tccttgaaaa     7080

tttggttttg gttaaaattt ttggtttatt tatttgaaat ccacactccc ttggaaactc     7140

ttaagtgcat ttgtgcactt ctgtttgttt gtctcaaaga agggactgta acaatctgag     7200

taatttccat gtcctcttcc ttattcctct agtggttgaa gctgtgtagc attttaacat     7260

atatatattc acaaatatat tcatataaac agtatacatt ttgaatcagt catttgttaa     7320

agaaaagtat attcaatgaa gatgaaattt aaataaaaaa ggacagagtc tatcctccag     7380

ggattgaaca ttttccaatt atctggtctt ttcctgttgt gcaaaaatga ctcattgctc     7440

cgaatgtcaa aaacaaatgc gacaaacaat ggcacttcat catttaaagt aatgttgcca     7500

agagaaaaaa tttcctggga gggaggtttc ccacaagcca aatctcctaa gcctcaaatg     7560

ctagcacttt ttggcagttg gataggaaat gagacattct ttggcagcca aaataagaga     7620

ggccgatggt gaaacttttt gagacaccct atggccttct tgtcaaaacc ttcactggag     7680

ctcaagaaaa gcatttctgt tgtgttattt gcagtgcaga tgatgtctgt gtaacaacat     7740

aatggttatt cacctttttt tgattttgat ttttgctgtg ttatcaaaaa cttgaatact     7800

gtgagaagaa gtgaattttc agttgacgaa tcagcatctt gttcccatgg tgataacact     7860

aattgaatat atctatgagg gcatgtatta gttaatggaa aaaaaaatac aacactaaca     7920

atacatagct gcaatgtgta caatggctga tttaattaaa taaaatgtac aagtgttaaa     7980

tgtggcaa                                                              7988


<210>  1623
<211>  1861
<212>  DNA
<213>  homo sapiens

<400>  1623
agcctactcg gtccggggtt gcgaactgta aggtctgagt tgctgcggcg caggcagcgg       60

agaccaagca gggatcttaa cagggtttag cgccacgcgg gccagggccg aggccggagc      120

tgggaggggc gcgcccggga aggggcggag ctgcggcggt ggcgccaaat cgcaaatatg      180

gcgccggagc ggctgcggag ccgggcgctc tccgccttca agttgcgggg cttgctgctc      240

cgtggtgaag ctattaagta cctcacagaa gctcttcagt ctatcagtga attagagctt      300

gaagataaac tggaaaagat aattaatgca gttgagaagc aacccttgtc atcaaacatg      360

attgaacgat ctgtggtgga agcagcagtc caggaatgca gtcagtctgt tgatgaaact      420

atagagcacg ttttcaatat cataggagca tttgatattc cacgctttgt gtacaattca      480

gaaagaaaaa aatttcttcc tctgttaatg accaaccacc ctgcaccaaa tttatttgga      540

acaccaagag ataaagcaga gatgtttcgt gagcgatata ccattttgca ccagaggacc      600

cacaggcatg aattatttac tcctccggtg ataggttctc accctgatga aagcggaagc      660

aaattccagc ttaaaacaat agaaacctta ttgggtagta caaccaaaat cggagatgcg      720

attgttcttg gaatgataac gcagttaaaa gagggaaaat tttttctgga agatcctact      780

ggaacagtcc aactagacct tagtaaagct cagttccata gtggtttata cacagaggca      840

tgctttgtct tagcagaagg ttggtttgaa gatcaagtgt ttcatgtcaa tgcctttgga      900

tttccaccca ctgagccctc tagtactact agggcatact atggaaatat taattttttt      960

ggaggtcctt ctaatacatc tgtgaagact tctgcaaaac taaaacagct agaagaggag     1020

aataaagatg ctatgtttgt gtttttatct gatgtttggt tggaccaggt ggaagtattg     1080

gaaaaacttc gcataatgtt tgctggttat tcaccagcac ctccaacctg ctttattctg     1140

tgtggtaatt tttcatctgc accatatgga aaaaatcaag ttcaagcttt gaaagattcc     1200

ctaaaaactt tggcagatat aatatgtgaa tacccagata ttcaccaaag tagtcgtttt     1260

gtgtttgtac ctggtccaga ggatcctgga tttggttcca tcttaccaag gccaccactt     1320

gctgaaagca tcactaatga attcagacaa agggtaccat tttcagtttt tactactaat     1380

ccttgcagaa ttcagtactg tacacaggaa attactgtct tccgtgaaga cttagtaaat     1440

aaaatgtgca gaaactgcgt ccgttttcct agcagcaatt tggctattcc taatcacttt     1500

gtaaagacta tcttatccca aggacatctg actcccctac ctctttatgt ctgcccagtg     1560

tattgggcat atgactatgc tttgagagtg tatcctgtgc ccgatctact tgtcattgca     1620

gacaaatatg atcctttcac tacgacaaat accgaatgcc tctgcataaa ccctggctct     1680

tttccaagaa gtggattttc attcaaagtt ttttatcctt ctaataagac agtagaagat     1740

agcaaacttc aaggcttttg agattcttaa agatcatctg aagaaaattc atcagttttc     1800

tgcttaactc tatatcttat gtgattctga tattacaata aaattatggt aaactttagg     1860

a                                                                     1861


<210>  1624
<211>  9794
<212>  DNA
<213>  homo sapiens

<400>  1624
tgtttccgtg cgcggccgct gcgcactcgg cactgggcgg cgctggctgg ctccctggct       60

gcggctcctc agtcggcggc ggctgctgct gcctgtggcc cgggcggctg ggagaagcgg      120

agtgttggtg agtgacgcgg cggaggtgta gtttgacgcg gtgtgttacg tgggggagag      180

aataaaactc cagcgagatc cgggccgtga acgaaagcag tgacggagga gcttgtacca      240

ccggtaacta aatgaccatg gaatctggag ccgagaacca gcagagtgga gatgcagctg      300

taacagaagc tgaaaaccaa caaatgacag ttcaagccca gccacagatt gccacattag      360

cccaggtatc tatgccagca gctcatgcaa catcatctgc tcccaccgta actctagtac      420

agctgcccaa tgggcagaca gttcaagtcc atggagtcat tcaggcggcc cagccatcag      480

ttattcagtc tccacaagtc caaacagttc agtcttcctg taaggactta aaaagacttt      540

tctccggaac acagatttca actattgcag aaagtgaaga ttcacaggag tcagtggata      600

gtgtaactga ttcccaaaag cgaagggaaa ttctttcaag gaggccttcc tacaggaaaa      660

ttttgaatga cttatcttct gatgcaccag gagtgccaag gattgaagaa gagaagtctg      720

aagaggagac ttcagcacct gccatcacca ctgtaacggt gccaactcca atttaccaaa      780

ctagcagtgg acagtatatt gccattaccc agggaggagc aatacagctg gctaacaatg      840

gtaccgatgg ggtacagggc ctgcaaacat taaccatgac caatgcagca gccactcagc      900

cgggtactac cattctacag tatgcacaga ccactgatgg acagcagatc ttagtgccca      960

gcaaccaagt tgttgttcaa gctgcctctg gagacgtaca aacataccag attcgcacag     1020

cacccactag cactattgcc cctggagttg ttatggcatc ctccccagca cttcctacac     1080

agcctgctga agaagcagca cgaaagagag aggtccgtct aatgaagaac agggaagcag     1140

ctcgagagtg tcgtagaaag aagaaagaat atgtgaaatg tttagaaaac agagtggcag     1200

tgcttgaaaa tcaaaacaag acattgattg aggagctaaa agcacttaag gacctttact     1260

gccacaaatc agattaattt gggatttaaa ttttcacctg ttaaggtgga aaatggactg     1320

gcttggccac aacctgaaag acaaaataaa cattttattt tctaaacatt tctttttttc     1380

tatgcgcaaa actgcctgaa agcaactaca gaatttcatt catttgtgct tttgcattaa     1440

actgtgaatg ttccaacacc tgcctccact tctcccctca agaaattttc aacgccagga     1500

atcatgaaga gacttctgct tttcaacccc caccctcctc aagaagtaat aatttgttta     1560

cttgtaaatt gatgggagaa atgaggaaaa gaaaatcttt ttaaaaatga tttcaaggtt     1620

tgtgctgagc tccttgattg ccttagggac agaattaccc cagcctcttg agctgaagta     1680

atgtgtgggc cgcatgcata aagtaagtaa ggtgcaatga agaagtgttg attgccaaat     1740

tgacatgttg tcacattctc attgtgaatt atgtaaagtt gttaagagac ataccctcta     1800

aaaaagaact ttagcatggt attgaaggaa ttagaaatga atttggagtg ctttttatgt     1860

atgttgtctt cttcaatact gaaaatttgt ccttggttct taaaagcatt ctgtactaat     1920

acagctcttc catagggcag ttgttgcttc ttaattcagt tctgtatgtg ttcaacattt     1980

ttgaatacat taaaagaagt aaccaactga acgacaaagc atggtatttg aattttaaat     2040

taaagcaaag taaataaaag tacaaagcat attttagtta gtactaaatt cttagtaaaa     2100

tgctgatcag taaaccaatc ccttgagtta tataacaaga tttttaaata aatgttattg     2160

tcctcacctt caaaaatatt tatattgtca ctcatttacg taaaaagata tttctaattt     2220

actgttgccc attgcactta cataccacca ccaagaaagc cttcaagatg tcaaataaag     2280

caaagtgata tatatttgtt tatgaaatgt tacatgtaga aaaatactga ttttaaatat     2340

tttccatatt aacaatttaa cagagaatct ctagtgaatt ttttaaatga aagaagttgt     2400

aaggatataa aaagtacagt gttagatgtg cacaaggaaa gttattttca gacatatttg     2460

aatgactgct gtactgcaat atttggattg tcattcttac aaaacatttt tttgttctct     2520

tgtaaaaaga gtagttatta gttctgcttt agctttccaa tatgctgtat agcctttgtc     2580

attttataat tttaattcct gattaaaaca gtctgtattt gtgtatatca tacattgttt     2640

tcaataccac ttttaattgt tactcatttt attcactaag ctcgataaat ctaacagtta     2700

ctcttaaaaa aaaaaaaaaa agactaaggt ggattttaaa aattggaaac tgacataatg     2760

ttaggttata atttctcatt tggagccggg cgcagtggct cacgcctgta atcccagcac     2820

tttgggaggc caaggtgggt ggatcacctg tggtcaagag ttcaagacca gcctggccat     2880

catggtgaaa ccccatctct actaaaaata caaaaattag ccaggcgtgg tggctggcgc     2940

ctgtaatccc agctactcag gaggttgagg cagcagaatt gcttgaaccc aggaggcaga     3000

gggttgcagt gagccgagat agcaccattg cactccagcc tgggcgactc catctcaaaa     3060

aataaaaata aaaaaaatgt ctcatttggg aaggaaattc cttttaaaaa agagttgaga     3120

cacttagaaa actaatgttt tatatttagt caagagttat ttaagaaagt caagcttgtt     3180

taacaacaaa atatgaagat ttaagtgtta attgctggat ccattttaaa ataagatttt     3240

aattaacatt tgtaaatggt atattttcgt ttgtaacaaa ccattgtctt ttttcaagga     3300

tgaacagagt ttatgaagga gcatcattct aagaattaag tgatgtagtc tttatgtttg     3360

gacagttcac cagattctca agaaggcttt caaacaacta taaagtttga tgtttgtcct     3420

gctgagctaa tggggaaagt tatagcataa aaattgtgta accgcataga tatgtcattt     3480

ttaaaaactg gtttaacaga aatcaagcaa agtcacaaat atgttcacaa gttggaatta     3540

tttattgagt caaaatgtcg aatcgaacat tttgaatgaa gtaagtgtta taaatgaaaa     3600

attgcctgat gtttagcagt ttgtattctc taaagctttt tttcaaaagt tcaggctttc     3660

tacttactgg gaagttggtg gtcctcttag tccctgataa atcaaggcaa tcacattcat     3720

gtgagctgga tgaatttata agttataaag accttatcct tcataccttg aggatgattg     3780

cactggtttt gaagtcagtt gcttaatgat gaggtgagaa atgtatcctg ttgctaaatc     3840

tgtcttagac ccttggtgaa acttgaagat ttcagtttat aaagataaaa tcaagcatct     3900

tttgtgcagt tttctttttt taatgcaaga atggtgggga ggtttgtttg taagcatgaa     3960

actttgagaa tctttattaa gaaaatgaca taatttttaa aaaccttgta gccaagaaca     4020

tatgtggcca cattaccagt aataaatgtt tttctcttta tattggccaa aagggaataa     4080

aaatgtcatc ataggaattt gtacatatgc tactgatttg cctagaaaat agcaagtttg     4140

atattgctca ctttgcaaat atagggccat gtggcacttt tatctatagg acagattaat     4200

aaaaatgaag tggggagggg tttatttttg atatattact cttatgagtt ttcaagcttt     4260

gataatgttt aactgaaaag tggcttagaa agggctagat ccaatgtgtt cattattaaa     4320

taattgctat cagatacaat tttaagttca ttctttttca aactcaagta ccatattggc     4380

aaccataata ttgtcatagg tgctctcttc atttagatat tcttgggggg ggtggcattt     4440

gtataatata tgtgtacata tatatatata tatatatata tacatacagt atataatcta     4500

aagctctgag agctcttaag tcaggaatgc tgagtattat agtatattga ggtcagatga     4560

aattttacat ttttgtgtgt tctgttgcat tccttctggt agtttctatg actgcattac     4620

tccagcactc atgattgatt ttatcttcta attttcttcc aagtatttta ttttttatta     4680

gttttctttg gcttgatact tttaaatatg ttactagtca cttgaaagcc tctcccccaa     4740

aagtatttgg tttgtatgct ttgtctgtgg cagctataac agtggtaaga acattttgaa     4800

gatagctttt taaaggaacc actgattttt tcaaaaatca tcctggggga ggaattttgg     4860

catttcattt gagcagggat tttgtcagaa aatgtgtttt gatggtaggt cagcagcagt     4920

gctagtctct gaaagcacaa taccagtcag gcagcctatc ccatcagatg tcatctggct     4980

gaagtttatc tctgtctctc aggataaatc cctgtaggac aaatccctac tatcatttct     5040

accttttggg gtgacatgtg gaatcataca aaggcttagg aagaaatacg tttgtttaaa     5100

ccaggatgct ttacttactt gaagtgactt caatctagat ttcttttaat atttaacaaa     5160

tttttaattc tatgatcagc cacagtcagc tattaccata aattggtctc tgtttatttt     5220

gaagatcacg gctgcttcat tttgcaggat taagtagggc taatgtatct taaagttaag     5280

atcttgaatt aaagtgagtt ttagaaatag tgttacatac cttttcagtt gttttcaaga     5340

ggctttattt ttgttgcctt tgtagccctg aaagctgttg gtatattttt tccctcatgg     5400

acccaataga aaagttgtat atttatttgg attatattta cattctgtcc tttgtaaatg     5460

tttggtgtaa cttgcacttt tttaaatgac ccagtttggg tattagcaac ttaagaaatt     5520

ccctcatcaa gtaattctca actttttagt ctttctcctc tcttcaaatc atgtgacttt     5580

ttaaatggaa gtttttcatt gattaaaata ttttagcacc taaaagctag ccttaaaaac     5640

agctgtaaaa gaaaaacatc aggaaattag atatgactag cccagttaat taaaagacgg     5700

gctcaaacct tgttttattc tttttcatct tggatgaaga ttgaagggaa aataactcaa     5760

gtgcataata tttattttca atttttaatg agactttatc ctcatcacaa cattaatact     5820

gtacatagta tgccaaaata tccattaatt tgtctagaat agtacaagac tttttaaagc     5880

aattgtcctc acagagacca catgtaatat actgaaatat gttcattttt aatggctttg     5940

ttaacatcaa agaaatgctg cctaaatttg atttcagatg aggaaggaga aagtaaagtg     6000

tgcatagtaa ggctgtaggt gaagagttgt gagataaata gttcactcag ttgtacaaag     6060

cacaactaga actttttgtt gggaggctta catacatctt gaatattctt aatgtaataa     6120

tgttgactat taagttggct acacagtcac tgtatgtact aggaactggt ttccttgaca     6180

ttctagaatc aatggctagg agaggcatta atctttgagg ggctgaacat atcatgaagc     6240

tgagtcagta tggaaaattt tcaaataaac agggtgctga agttccatct gtctcatctg     6300

cttatgataa gttcttattg attagtgaat gtagcttaag cctttgtatg tgtcctcagg     6360

gggcagaccg actttaagag ggaccagata acgtttgaat ggagggatta tatttcaggt     6420

gttttagctt gaaatttatt ttttaaaaaa agaaaaattt aaaaaatata taaataaaat     6480

agaacaaagc cggtgatgca agttgatatt ataaacaggc agttttagca cagaaagaaa     6540

atactgacct gtctgcattc tggtacggtg ggtgcaggtc ccagctgggt atgacatgat     6600

acatttttaa ttattctcac cagcaagtaa aaggaaaatg aacaatcttt tggaattgtc     6660

tttgaaaagg atcaaagagt aggaaattca catttgacct aacattactt gcctatagaa     6720

gtatggcatt tccaagcttt tgtctgagga gcatctcaga gaagtgagag taaatctgag     6780

ttagcttaaa aattggtagg gaggaagaaa atctctgcaa ataatgattt tatgtttgtt     6840

ggccaagtga aatgatctat cattgtgttt gggaggtttt attttcttat gtttttaaaa     6900

ttggtaaatg ctttatagat gtatttttat ccaagtgcca ctccaatttg tgtatgtaat     6960

aaaattattt atattaaaag tgggaaataa ttgtcaacat tttttttgag tatagattta     7020

ttaggggtgg caaagaagag tgctagttag cagttttcca tgtaaagttg tccttgactg     7080

atttgtccac atgtcagttg taactccccc actccctgca aaaggaatta tttctaaccc     7140

agatgtatca cttgaaactt tttagaagca aaataatcag ggaagttcct agaaaggtgt     7200

ttggcttttt ggtttttgag ggttggggta aagaagactt cccccacaac tgtcagcaca     7260

aaacagggta ttgattttta actctgatgt ttctattgga gttgaatact aaataaataa     7320

ctataatgag ggaaatacat ttctaataaa attccctaca ttctagaaac atccctgttt     7380

taattttttt atctaaatct ttttgtgctt tatgtgtaaa gaaaaaaatg tactgagtta     7440

caatgcattt tattaacact atgtacataa tagctgcttt gtgttcagaa tagtagcagt     7500

tgctttgtat attaaagtga tccttgtgaa tttgtgaaat attgtcataa agtgcttttt     7560

cttactgtaa tctttgtggt atcaactgtc ataatgctct ttttacacaa acatttatgt     7620

gcagtcacat aaacatgctt ttaaaaactc tgtaagtctc ttttttgggg atgggatctc     7680

tatattttgt tgggtttttt ttgctagtag tgtgaagcca tgttttattg gacttaaagt     7740

tacaatatat tacaagcttg tgttggaagg cagcaaaact aattcagaca acaacatgtc     7800

ttcagttact ggatccctaa ttttcaggac aaaacctgtt tttcaataag attgaacagt     7860

gcctatttgt ggatttggag atgttactgt caagatgact aatggagaca tacgaccagc     7920

tgtgtctgat gtcataaaac acgtgttcac tgaaaggaca ataagactat ataccttctc     7980

aggtcccctt gcaattctaa aactctgtga tcatataaat tggaaggaaa ggggagggga     8040

tatggttaat ctttgcttaa gctgtaagaa taaaaaagtt atctcctata ctattaactt     8100

ctgaaataag ttctgagacg agacatctga aaataagcag ctgcattatt tgtatgtttc     8160

ttcactgcca agatgtgttc aagcctgcta tacctgccat tgtattggaa ggcttaatga     8220

atttcattta ttttctgcaa caacgattac agaatttatt gcacaaaatg agacattttg     8280

agagtgatat taattacatg agggacaata ggcatgaact aggattgttc taagcaaatc     8340

ggaatcgggt caccctgcca cgttcaggtg cttggacctt caggaaaaga ttgcccatct     8400

tgtcatttga ccaggcactg aagtgacaag accatccttg agaagtcaca tccaaagata     8460

aaattctgat ccatttctag ttttagtgtt tcgccactga agacttaaca tatgtctttt     8520

acactcaggt tgcaaaacac aggcccaaga caaacttaac ttctccccca aatcttcctt     8580

ccgctggttt ttccatctcg taagtggtgc cactatccat ctgttaaatt gtttagggga     8640

aacctagaaa agcactacct taatcagtgt tatccttctt cttaactgtg cgtcctaatt     8700

tctccacatc tttcttaagt gcagtgacca aaccggatga gaattctaac acgggcctga     8760

catcaaatgg aaaggaagga taatgtccag gagttggaat gttatccttg tttttaatta     8820

agatgcaatt cacataaatt aactttttaa gtgaacaatt aagtggtagt acatccacaa     8880

tggtgtacaa ccaccacttc tatctagctc caaaacattc tcatcactcc aaaagtaaag     8940

tcccgttact ctccattttc tcctcccacc gcccttgtcc ctggcaacca ccaatctgct     9000

tcctgtttct ttggatttac atccgggtat ttcatgtgag actcatacac tgtgtattac     9060

ttctttcgtc tagctttaat gtgttgttga ggttgatcca ttgtaacatg ttatcactac     9120

ttcattcctt tttatagcta agtatacttt ttatagtaag tatgccattg tagatatata     9180

ccacaagttt atcgattcat ccagttgagt tgtttctact gtttggctaa tgttcatagt     9240

gctgttatga atgttcgtgt acaagtattt gagtccgtgt tttcaattat ttggggtata     9300

tgcctgggag tggagttgct gggtcatgtt gaaatcgcac atttaacttt ttgaggaact     9360

gtcaaacttt ccctcagcag ctgtaccgtt ttaccttcca ccattgatgt atgagggttc     9420

caatttctcc acaccttcac caacacttat tttgccattt taaaaattat agccatcctc     9480

atgggtgtgg tctctcattg tggttttgat ttgcatttcc ctgattacta atgatgtgga     9540

gcatcttttg ttgtctttgg ccatctgcgt atcttctttg aagaaatgtc tgttgaggtc     9600

ctttgttcat tgaaattttg ttgttgggtt ctgagttcct tatatattct gggtactagg     9660

cccttataat attttcgcct ataagttttt gctttataat gtcctcattg ttttcaaact     9720

tactttatgt aatatgtaca cttctaaaaa aaagaaacat ggaaaagggc aaactgtaaa     9780

aaaaaaaaaa aaaa                                                       9794


<210>  1625
<211>  4625
<212>  DNA
<213>  homo sapiens

<400>  1625
atacctacac cggctttttg tacgactgtt ggccctggag aacgatcctt tggtggcgag       60

ggcggggagg acgaaagcgc ccactgtgga ttggacagtg tcaaaaagag gggcggtccc      120

tactgaaggg gcggttgggc gacgaaggga agagtctttt cagcgctgag gactggcgct      180

gaggaggcgg cggtggctcc cggggcgttt gagcgggctc acccgagccc gcgggccaac      240

gcggatccag gcccgactgg cgggaccgcc ccggattccc cgcgggcctt cctagccgcc      300

atggaggacg gcgtctatga acccccagac ctgactccgg aggagcggat ggagctggag      360

aacatccggc ggcggaagca ggagctgctg gtggagattc agcgcctgcg ggaggagctc      420

agtgaagcca tgagcgaggt ggaggggctg gaggccaatg agggcagtaa gaccttgcaa      480

cggaaccgga agatggcaat gggcaggaag aagttcaaca tggaccccaa gaaggggatc      540

cagttcttgg tggagaatga actgctgcag aacacacccg aggagatcgc ccgcttcctg      600

tacaagggcg aggggctgaa caagacagcc atcggggact acctggggga gagggaagaa      660

ctgaacctgg cagtgctcca tgcttttgtg gatctgcatg agttcaccga cctcaatctg      720

gtgcaggccc tcaggcagtt tctatggagc tttcgcctac ccggagaggc ccagaaaatt      780

gaccggatga tggaggcctt cgcccagcga tactgcctgt gcaaccctgg ggttttccag      840

tccacagaca cgtgctatgt gctgtccttc gccgtcatca tgctcaacac cagtctccac      900

aatcccaatg tccgggacaa gccgggcctg gagcgctttg tggccatgaa ccggggcatc      960

aacgagggcg gggacctgcc tgaggagctg ctcaggaacc tgtacgacag catccgaaat     1020

gagcccttca agattcctga ggatgacggg aatgacctga cccacacctt cttcaacccg     1080

gaccgggagg gctggctcct gaagctggga gggggccggg tgaagacgtg gaagcggcgc     1140

tggtttatcc tcacagacaa ctgcctctac tactttgagt acaccacgga caaggagccc     1200

cgaggaatca tccccctgga gaatctgagc atccgagagg tggacgaccc ccggaaaccg     1260

aactgctttg aactttacat ccccaacaac aaggggcagc tcatcaaagc ctgcaaaact     1320

gaggcggacg gccgagtggt ggagggaaac cacatggtgt accggatctc ggcccccacg     1380

caggaggaga aggacgagtg gatcaagtcc atccaggcgg ctgtgagtgt ggaccccttc     1440

tatgagatgc tggcagcgag aaagaagcgg atttcagtca agaagaagca ggagcagccc     1500

tgaccccctg cccccaactc cattatttat tacggagctg ccccgcctgg gtggccggac     1560

ccctgggcct tggggctgtg gatcctggtt ccctgtttgg aaaattcacc acctctagct     1620

cctcactgtt ctttgtaatt aacacgctgt tggtaatctt attaattatt taaccacttg     1680

gcctgctgac cccctcattt cttggggttg acagagtcga ggtgctccgt ggagccagcc     1740

tgtttccctg gacaggggcc tggacccgcc tgtctctggg tgctgcctgg gctgtcccgg     1800

tgggtctgtt ctggtttcac cccgagccca gcaggagtgg agtaaaggga gaaggttaat     1860

atggtgggag tctggagttg gaattggccg gggacagagt ttagaatgca gggattcagg     1920

gtcaaggtct agcattcatt ctagaagtta cttgacagcc atcagccagt tacgctacag     1980

ccatcagcta gttcccatcg ttgctttcat ggggcttgag gtctttgagg ggcaggagat     2040

gaagctggtg aggttgtgag ctgggccagg gctttgagga caacctggag ctggaagaac     2100

atgcgaccac ctcagggagg gtcagggaag gatgagtggg gaggtggccc atgtcctgca     2160

agggccttgc tgatgggatg tcctgaaggg ctgggcagcc ttagatcggg ctaagagggc     2220

aggactgtgg gccagtgcca gagccaggct tgtctgttct caaaggatca gcctcctttg     2280

gaggacattt tgtgtcaagg atagggctga ggacctgcgt tctgaacgtc tttcctggga     2340

ttcttgacag ccaaagaaat tcgaggatcg cctctatgaa ggtgaagtct tggcatgtgg     2400

ggtacccctg aatcctgggc taaggtctgt gaccttttgc cctccagttg gggtatgtgt     2460

ggtgtcccca aagaacaagg gctcgtggat cccgagcagg gtgcgatggc ggattgggag     2520

gtcccatgtc actctcccat gcccgccttt gaagctgagg cgctctttag ttaacaaact     2580

acaagtccca gcagggaccg ggacgcgggt gggagaggcg cctgtggccc cgaggcgtgc     2640

cgcgagttgt agtccctcct gcccgctgtg ttcgcttttg agctctccga tgggatgcgg     2700

cgcttcggaa tttcgggctt tgatccctgt cccgcccttg gccacaggca cctgccggcc     2760

tgaaggcccc cgcggtgggg gtaccctgcg cccctccgcg ggaaggtgga ctacagttat     2820

cggcaggctg tgcggcgcca aagccacggt gacccagacc cgaggttttt ccgggcgtcg     2880

cagtttcccg agactccgtg gcggcgtttg tcttcttttt cttagtcaga tcccgtactt     2940

ttgtggaggg tagaggaggc tttgaccgcc gcggccccgg gggctggtgg gaaatggagt     3000

tccaaatgag aaaatagaat tccccacttc tctttcccac aggtgccagg gaaacggagt     3060

catcgaccca agaaggtcgt gggagatgag gtcccagggt aaacagcggg tcccgccact     3120

atgtcaccct ttcctgccgc ctccccggat gaactgcatg cagggcggcc ggctccgtgg     3180

caggcagagg caggaagagg cgcggagccc gctggtggcg aagaggggag tgcggcggga     3240

ggggagggca gaggcaggcg gccggtcgcg tggggcctgg gccgccccag gagggcctct     3300

ggctggattc ttagcagatg gaagccgtgc aagggcagga ggcaggggcc tgacgtgttt     3360

ggattgaggt tgcaggaggg gcccctggct gcttcaggga gaataatttg gaggcgagcg     3420

gggaggtgag aggaagctgt gcggtgcagg atggcgtggc tgtggaggtg gagaacgttg     3480

ggccacgcta ggagtcttga aagaggagcc aaaaggactt gctgagagcc gccgcagctg     3540

gtgaatgacg gtgccatgac tgaggtggtc gaaagggagt atttaagggg aaatcaggca     3600

ttccgttttg accaaattaa gctggagatg cctgtggaac attccagcca ggctgcatca     3660

cgtcacactg accttcagca ttgcccacag tccatcttcc cccaggacct gaggattttg     3720

cgtccggctc cctcctcgcc caggaccccc aagctcccag cacgcttctg attttttttg     3780

taggtttttt tttttgtttt ttgttttgtt ttgttttgtt tttgagaggg agtctcactt     3840

tgtgccctag actggagtgc aatggcgcca tctcggctta ctgcaacctc cacctcccag     3900

gtgcaagcga ttcccctgcc tcagcttccc gagtagctgg gattacagat gtgagccacc     3960

gtacccagct aatttttgta tttttagtag agacggggtt tcaccatatt ggccaagctg     4020

gtctcgaact cctgacctca ggcgatccat ctgtctcagc ctcccaaagt gctgggatta     4080

caggtgtgag ccaccgcgcc aggcctcagc ccacttcttt tgggtggcaa tggtttggat     4140

atcgtttgtc ctcactaaaa ttcatgttga gattcgagcc ccagtgtggc aggtgttggg     4200

atgtggggcc tcataaggag ctgtgtggtc ttggaggtgg agtcctcatg gatagattaa     4260

tgcctgcctt aaggggtgag tgagtgctca cccttgggaa tttgggaatt tggttttctc     4320

tcccttgctt ccttcagcac catgtgatct ctgtgcacac agctgcatcc ttctgccctc     4380

ccccagaagc agcagcagcc tcagggatga gggaggtcct cagtgagtgc acctgcccag     4440

tcttgaacct tccagccatc agaatctgag ccaaatcaac ctcttccttt ataaagaccc     4500

agcctcaggt cttctgtcag agcaacacaa aatggactca gcacggatca aattgtgtct     4560

cccccacccc cacaaaaaac tttatattaa aatcctaacc cccagcaaaa aaaaaaaaaa     4620

aaaaa                                                                 4625


<210>  1626
<211>  3831
<212>  DNA
<213>  homo sapiens

<400>  1626
gggtcgtcag ggcgacgaaa aaggggaagg ggtgctgggc ctggcgggca aactaaggct       60

gcggaccgtt gggcggttcc gcggggcgtt gtccggagag ctgcgaggcc ggggttccca      120

gggttcacgc cacactctag gaagtgcctg agctagtgag ctggccaacg agctccgcgg      180

gctgggacca tgggctgctt cttctccaag agacggaagg ctgacaagga gtcgcggccc      240

gagaacgagg aggagcggcc aaagcagtac agctgggatc agcgcgagaa ggttgatcca      300

aaagactaca tgttcagtgg actgaaggat gaaacagtag gtcgcttacc tgggacggta      360

gcaggacaac agtttctcat tcaagactgt gagaactgta acatctatat ttttgatcac      420

tctgctacag ttaccattga tgactgtact aactgcataa tttttctggg acccgtgaaa      480

ggcagcgtgt ttttccggaa ttgcagagat tgcaagtgca cattagcctg ccaacaattt      540

cgtgtgcgag attgtagaaa gctggaagtc tttttgtgtt gtgccactca acccatcatt      600

gagtcttcct caaatatcaa atttggatgt tttcaatggt actatcctga attagctttc      660

cagttcaaag atgcagggct aagtatcttc aacaatacat ggagtaacat tcatgacttt      720

acacctgtgt caggagaact caactggagc cttcttccag aagatgctgt ggttcaggac      780

tatgttccta tacctactac cgaagagctc aaagctgttc gtgtttccac agaagccaat      840

agaagcattg ttccaatatc ccggggtcag agacagaaga gcagcgatga atcatgctta      900

gtggtattat ttgctggtga ttacactatt gcaaatgcca gaaaactaat tgatgagatg      960

gttggtaaag gctttttcct agttcagaca aaggaagtgt ccatgaaagc tgaggatgct     1020

caaagggttt ttcgggaaaa agcacctgac ttccttcctc ttctgaacaa aggtcctgtt     1080

attgccttgg agtttaatgg ggatggtgct gtagaagtat gtcaacttat tgtaaacgag     1140

atattcaatg ggaccaagat gtttgtatct gaaagcaagg agacggcatc tggagatgta     1200

gacagcttct acaactttgc tgatatacag atgggaatat gaagtgcaat gtggaaccag     1260

gacttggtat taagcctttc ccaacttgtg aatatagaat ttgataatac acttttgtgt     1320

attagcaatg gtttttacta atgctaaaac ttttaaagtt tattttttaa taaattgttg     1380

agtattacat catttacttg aggttcaaaa ataattcatt ttaaattaag tagttttaat     1440

cagcttaaaa gctatttaac ccattttaat aagcttgcag ttttgtttct ctgcatatga     1500

tattcttatt agaaaacaga agtagctaaa agtttattat tttaatccta tttaaatgtt     1560

ctttcaaatc tctaataatt taaactttcc tcagtgctcc atgatacttt ttttgagact     1620

ccatatcatt gcttatttta cctttttcaa tttagaggga tttgttacta gtcgatcaat     1680

tagaatgaac ctatgcacat ttttatgtac acatatccag ttatataatt gcttcctagt     1740

tgcattatat ggcaaatgag attttgtaca tggagttgac ataatacttt gtaaattgaa     1800

ttttttaaag aaataggcat ttgataacca gcttggcaag taactctact aacagatgtt     1860

ggtatagcta tttaaagact acttcgtaag tagtatgatt atttgaataa attacacatt     1920

gtttagtttt ttaatacaac tgctatatga ctcttctgct tcctgataag aaaaggtata     1980

tgcaatgcta aaactgtaga agcccaatca ccagcagttt ttaaaaaggt gataactttt     2040

attagctctt gtgggctatc aagagaattg gaacaaaacc ttgtgacttt taggtaagaa     2100

ataggcatga tgataagcta tgcagattat taaaaagctt gatacatttg atttttcatt     2160

agatatgcca ttcatatcaa gtaatgttca agtatgataa aattattttg gttgctttaa     2220

agcactgttt cccaaatcta cctgatcata ataatttacc aggaagcaga ggagagctac     2280

ttgtttaaaa atccacattc ttggacccaa tcctcagatg cacggattca gtcttcaggg     2340

gaaactctgt tttaaggggt atgttgtaat ctaaagtaat tggttcagga ggtgtcaata     2400

ggttgaactt gtgagaaggc actgaatctg ccatccacat cacatatagc agctattatg     2460

aaatcagctt tcataggcct atttttaaaa ggaatctgaa atttaattct attttgataa     2520

aactaagact gaaaataacc acttgtaaac attcctatga ttgttactaa aatgtatttt     2580

catgtttaaa atgtttttgg atatttttgg gttaataact actacattga attgcatgtt     2640

aaggtgcaga aataatacat taaaagattt tcactttaaa ttaattagta atattgagcg     2700

ctcaccctgt gcgtggcctt gtgctaacca ttagcactgc atcatttcaa ttcttttata     2760

agggcattca atactacaaa atcaacatga tttcataagg tgcaaataaa agttggtgac     2820

agatttaata taattttgat cacaatttac aaatgatctt tgcaaatagt ggtcagacgg     2880

cattagtttt tcccttagtt aagctaaatt aaagggactc catcctgtta tgattatatt     2940

attattatta ttattattat ttttgaggtg gagtttcact cttgttgccc aagctggagt     3000

gcaatggcgc gatctcggct caccacaaca tccgcctcct gggttcaagc gattctcctg     3060

cctcagcctc ctgagtagct gggaatacag gcatgcgcca ctacacctgg ctaatttttg     3120

tatttttagt tgagatgggg tttttccacg ttggtcaggc tggtctcgaa ctcctgacct     3180

caggtgatcc gtccacctca gcctcccaaa gagctgggat tacaggtgtg agctaccgcg     3240

cctggccatg atgatattat taaacaccat tattcacatt tcaaataata acaatacttt     3300

ttgtttttca aaaataaaat gcaatgttat ataaagctat aaactaagtt ctttatgata     3360

tttgagcaac aactcaggaa tataacatat aagggagatg ttaatttaaa aatttccact     3420

acacttatta tctattaacc aaagcttaaa attttgtatt cttctgttag ataagacctt     3480

ttacccattt aatttgtctt taaggacagt catttggctt ctgaatgttt gaaacgattt     3540

taaaaaataa gtagtgctat ggttgtttct ataattctaa cctttgatag taatcagaat     3600

gtattacatt tcatttctga atagcttttg aatttatgaa aaattattaa caatgaaaaa     3660

ttggtaattt tattaagtta tatgtgttta aatattatat tagcttattt ctcttgcatt     3720

aatagtactg ctgtttttgt tttgcttctt tatatttatg tctagctttt atatgtaatt     3780

tatctagtgt ttataaaatg tgatttgtaa taaatgttgt taaaatgaaa a              3831


<210>  1627
<211>  512
<212>  DNA
<213>  homo sapiens

<400>  1627
attcttcccc tctctacaac cctctctcct cagcgcttct tctttcttgg tttgatcctg       60

actgctgtca tggcgtgccc tctggagaag gccctggatg tgatggtgtc caccttccac      120

aagtactcgg gcaaagaggg tgacaagttc aagctcaaca agtcagaact aaaggagctg      180

ctgacccggg agctgcccag cttcttgggg aaaaggacag atgaagctgc tttccagaag      240

ctgatgagca acttggacag caacagggac aacgaggtgg acttccaaga gtactgtgtc      300

ttcctgtcct gcatcgccat gatgtgtaac gaattctttg aaggcttccc agataagcag      360

cccaggaaga aatgaaaact cctctgatgt ggttgggggg tctgccagct ggggccctcc      420

ctgtcgccag tgggcacttt tttttttcca ccctggctcc ttcagacacg tgcttgatgc      480

tgagcaagtt caataaagat tcttggaagt tt                                    512


<210>  1628
<211>  2592
<212>  DNA
<213>  homo sapiens

<400>  1628
tcccgcccgc gccctgccca ccccggccgc gcgcaccaca acgcccccgc cccgccgccc       60

ggaaccagct gagcgcagct ggacccagca gccgctgtct ccagtgccgc agcagcagcc      120

caacagcatg gtggtggaac accccgagtt cctcaaggca gggaaggagc ctggcctgca      180

gatctggcgt gtggagaagt tcgatctggt gcccgtgccc accaaccttt atggagactt      240

cttcacgggc gacgcctacg tcatcctgaa gacagtgcag ctgaggaacg gaaatctgca      300

gtatgacctc cactactggc tgggcaatga gtgcagccag gatgagagcg gggcggccgc      360

catctttacc gtgcagctgg atgactacct gaacggccgg gccgtgcagc accgtgaggt      420

ccagggcttc gagtcggcca ccttcctagg ctacttcaag tctggcctga agtacaagaa      480

aggaggtgtg gcatcaggat tcaagcacgt ggtacccaac gaggtggtgg tgcagagact      540

cttccaggtc aaagggcggc gtgtggtccg tgccaccgag gtacctgtgt cctgggagag      600

cttcaacaat ggcgactgct tcatcctgga cctgggcaac aacatccacc agtggtgtgg      660

ttccaacagc aatcggtatg aaagactgaa ggccacacag gtgtccaagg gcatccggga      720

caacgagcgg agtggccggg cccgagtgca cgtgtctgag gagggcactg agcccgaggc      780

gatgctccag gtgctgggcc ccaagccggc tctgcctgca ggtaccgagg acaccgccaa      840

ggaggatgcg gccaaccgca agctggccaa gctctacaag gtctccaatg gtgcagggac      900

catgtccgtc tccctcgtgg ctgatgagaa ccccttcgcc cagggggccc tgaagtcaga      960

ggactgcttc atcctggacc acggcaaaga tgggaaaatc tttgtctgga aaggcaagca     1020

ggcaaacacg gaggagagga aggctgccct caaaacagcc tctgacttca tcaccaagat     1080

ggactacccc aagcagactc aggtctcggt ccttcctgag ggcggtgaga ccccactgtt     1140

caagcagttc ttcaagaact ggcgggaccc agaccagaca gatggcctgg gcttgtccta     1200

cctttccagc catatcgcca acgtggagcg ggtgcccttc gacgccgcca ccctgcacac     1260

ctccactgcc atggccgccc agcacggcat ggatgacgat ggcacaggcc agaaacagat     1320

ctggagaatc gaaggttcca acaaggtgcc cgtggaccct gccacatatg gacagttcta     1380

tggaggcgac agctacatca ttctgtacaa ctaccgccat ggtggccgcc aggggcagat     1440

aatctataac tggcagggtg cccagtctac ccaggatgag gtcgctgcat ctgccatcct     1500

gactgctcag ctggatgagg agctgggagg tacccctgtc cagagccgtg tggtccaagg     1560

caaggagccc gcccacctca tgagcctgtt tggtgggaag cccatgatca tctacaaggg     1620

cggcacctcc cgcgagggcg ggcagacagc ccctgccagc acccgcctct tccaggtccg     1680

cgccaacagc gctggagcca cccgggctgt tgaggtattg cctaaggctg gtgcactgaa     1740

ctccaacgat gcctttgttc tgaaaacccc ctcagccgcc tacctgtggg tgggtacagg     1800

agccagcgag gcagagaaga cgggggccca ggagctgctc agggtgctgc gggcccaacc     1860

tgtgcaggtg gcagaaggca gcgagccaga tggcttctgg gaggccctgg gcgggaaggc     1920

tgcctaccgc acatccccac ggctgaagga caagaagatg gatgcccatc ctcctcgcct     1980

ctttgcctgc tccaacaaga ttggacgttt tgtgatcgaa gaggttcctg gtgagctcat     2040

gcaggaagac ctggcaacgg atgacgtcat gcttctggac acctgggacc aggtctttgt     2100

ctgggttgga aaggattctc aagaagaaga aaagacagaa gccttgactt ctgctaagcg     2160

gtacatcgag acggacccag ccaatcggga tcggcggacg cccatcaccg tggtgaagca     2220

aggctttgag cctccctcct ttgtgggctg gttccttggc tgggatgatg attactggtc     2280

tgtggacccc ttggacaggg ccatggctga gctggctgcc tgaggagggg cagggcccac     2340

ccatgtcacc ggtcagtgcc ttttggaact gtccttccct caaagaggcc ttagagcgag     2400

cagagcagct ctgctatgag tgtgtgtgtg tgtgtgtgtt gtttcttttt ttttttttta     2460

cagtatccaa aaatagccct gcaaaaattc agagtccttg caaaattgtc taaaatgtca     2520

gtgtttggga aattaaatcc aataaaaaca ttttgaagtg tgaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aa                                                         2592


<210>  1629
<211>  6801
<212>  DNA
<213>  homo sapiens

<400>  1629
gcaagtgaac cggagcaaac gacttccgat ccagtctgcg ctgttgcggc tcccgtttgg       60

gatttgattt gcagcatctt tgagcctcta cgacaaaaaa ccgcgaagca cgcccagccc      120

tcccccggca ccccgaaaag cacccactcc ctcccgggga cacagctggg cgcgtccaca      180

cccccgcagc cccacaccat gttgtgcgga aggacttcca ctccccgcct gtgtcgttga      240

tgtcagaccc caggccagcc tccgggcgct gcagttctcc cggctaatgc tgaggctgcg      300

gctccggctc tagcacaggc accagccgcc gccgcacccg gccccagcgc ccaccgtctg      360

catgtgcccg ccgtagccgt ctgcccagcc cgcagcccgc gctccacgga gcgctggaga      420

ccaccgtggg gggccccttc tgccctcgag agaagcggtc ttggaggtat tgatttaggt      480

ggttggattt tttccgtgga tctatcaatt cacaattcga atttggaaga aagaaggaaa      540

acatgacgtc tccagccaaa ttcaaaaagg ataaggagat catagcagag tacgatactc      600

aggtcaaaga gatccgtgct cagctcacag agcagatgaa atgcctggac cagcagtgtg      660

agcttcgggt gcaactgttg caggacctcc aggacttctt ccgaaagaag gcagagattg      720

agatggacta ctcccgcaac ctggagaagc tggcagaacg cttcctggcc aagacacgca      780

gcaccaagga ccagcaattc aagaaggatc agaatgttct ctctccagtc aactgctgga      840

atctcctctt aaaccaggtg aagcgggaaa gcagggacca taccaccctg agtgacatct      900

acctgaataa tatcattcct cgatttgtac aagtcagcga ggactcagga agactcttta      960

aaaagagtaa agaagtcggc cagcagctcc aagatgattt gatgaaggtc ctgaacgagc     1020

tctactcggt gatgaagaca tatcacatgt acaatgccga cagcatcagt gctcagagca     1080

aactaaagga ggcggagaag caggaggaga agcaaattgg taaatcggta aagcaggagg     1140

accggcagac cccacgctcc cctgactcca cggccaacgt tcgcattgag gagaaacatg     1200

tccggaggag ctcagtgaag aagattgaga agatgaagga gaagcgtcaa gccaagtaca     1260

cggagaataa gctgaaggcc atcaaagccc ggaatgagta cttgctggct ttggaggcaa     1320

ccaatgcatc tgtcttcaag tactacatcc atgacctatc tgaccttatt gatcagtgtt     1380

gtgacttagg ctaccatgca agtctgaacc gggctctacg caccttcctc tctgctgagt     1440

taaacctgga acagtcgaag catgagggtc tggatgccat cgagaatgca gtagaaaacc     1500

tggatgccac cagtgacaag cagcgcctca tggagatgta caacaacgtc ttctgccccc     1560

ctatgaagtt tgagtttcag ccccacatgg gggatatggc ttcccagctc tgtgcccagc     1620

agcctgtcca gagtgagctg gtacagagat gccaacaact gcagtctcgc ttatccactc     1680

taaagattga aaacgaagag gtaaagaaga caatggaggc caccctgcaa accatccagg     1740

acattgtgac tgtcgaggac tttgatgtgt ctgactgctt ccagtacagc aactccatgg     1800

agtccgtcaa gtccacggtc tctgaaacct tcatgagcaa gcccagcatt gctaagagga     1860

gagccaacca gcaagagaca gagcagtttt atttcacaaa aatgaaagag tacctggagg     1920

gcaggaacct catcaccaag ttacaagcca agcatgacct tctgcagaaa accctgggag     1980

aaagtcagcg gacagattgc agtctagcca ggcgcagctc aactgtgagg aaacaggact     2040

ccagccaggc aattcctctg gtggtggaaa gctgtatccg gtttatcagc agacacggac     2100

tacagcatga aggaattttc cgggtgtcag gatcccaggt ggaagtgaat gacatcaaaa     2160

atgcctttga gagaggagag gaccccctgg ctggggacca gaacgaccat gacatggatt     2220

ccatagctgg tgtcctgaag ctttacttcc gggggctgga acaccctctc ttccccaagg     2280

acatctttca tgacctgatg gcctgcgtca caatggacaa cctgcaggag agagctctgc     2340

acatccggaa agtcctccta gtcctgccca aaaccactct gattatcatg agatacctct     2400

ttgccttcct caatcattta tcacagttca gtgaagagaa catgatggac ccctacaacc     2460

tcgccatctg cttcgggccc tcgctaatgt cagtgccaga gggccacgac caggtgtcct     2520

gccaagccca cgtgaatgag ctgatcaaaa ccatcatcat ccagcatgag aacatcttcc     2580

caagccccag ggagctggag ggccctgtct acagcagagg aggaagcatg gaggattact     2640

gtgatagccc tcatggagag actacctcgg ttgaagactc aacccaggat gtgaccgcag     2700

agcaccacac gagcgatgac gaatgtgagc ccatcgaggc cattgccaag tttgactacg     2760

tgggccggac agcccgagag ctatccttta agaagggagc atccctgctg ctttaccagc     2820

gggcttccga cgactggtgg gaaggccggc acaatggcat cgacggactc atcccccatc     2880

agtacatcgt ggtccaagac accgaggacg gtgtcgtgga gaggtccagc cccaagtctg     2940

agattgaggt catttctgag ccacctgaag aaaaggtgac agccagagcg ggggccagct     3000

gtcccagtgg gggtcatgta gccgatattt atcttgcaaa catcaacaag caaaggaagc     3060

gtccagaatc tgggagcatc cggaaaactt ttcggagtga cagccatggg ctgagcagtt     3120

ccctgactga ctcctcctcc ccaggggtgg gggctagctg ccgcccatcc tcccagccca     3180

tcatgagcca gagcctcccc aaagaagggc cagataagtg ttccatcagt gggcacggga     3240

gcctcaactc catcagccgc cactcatccc tgaagaatcg gctggatagt ccacagatcc     3300

ggaagactgc cacagcggga aggtcaaaaa gcttcaataa ccatcggccc atggaccctg     3360

aggtcattgc tcaggatatt gaggcaacaa tgaactcggc cctgaatgag ctacgggaac     3420

tagaacggca gagcagtgtc aaacacaccc ctgacgtggt tctggacacc ttggagcccc     3480

tcaaaacctc cccagtggtg gcccccacgt cagagccctc cagccctctg cacacccagc     3540

tcctcaagga ccccgagccc gccttccagc gcagcgccag tactgctggg gacatcgcct     3600

gcgccttccg gcctgtcaag tctgtcaaga tggctgcccc ggtcaaacca ccagccacac     3660

ggcccaagcc cactgtcttc cccaaaacaa atgccactag ccctggtgtc aactcatcaa     3720

cttccccaca gtctactgac aagtcttgta ctgtctgagg gataataatt taattgttct     3780

agacaagggg actataggga ctgactgtta ttaaaatctt cctatttaac tagcttgggg     3840

acttcagttg aaaattaggt tctaagttgt tcttgcagga attagcctcc ccgtctccca     3900

aaaccttgag aatgaagccc ttggtatcgc ctctcccttc ccactgccct ctgcttcccc     3960

cagtcgtcgt aattcagcca gctgcagtcc gtaccgttct taggttagcc agagacaggt     4020

tttcattatc aggtcactgt gaaatctggt aaggcagtcc tgaggacatg ggctcaagtc     4080

tcagtcccct cagaccacgg tgatgccttg accagatggt tggctactgc catccagctt     4140

tcagtggcat cttgttttgg gaactgatta tagagaatca tatatagtcc agtcttcatt     4200

ttacatacac acacatattt tacacacaca cacattttac acacacacac acacacacac     4260

acacacatat gtttttctag tctctggcat gtgtagcctc tcctggtcat agaccagtct     4320

ctttgtaagt tattgtggca gttcacacag tagccaccag gggtctctgt ttccatcaca     4380

aactttgttc tgtctgggcc agagaaccta gcctttgaaa tctctccatc atatgaaaca     4440

taacgggatg ggacaatccc gtaacctgtt tggggttggg ggctttctct ctgtgttctt     4500

tccattgatg tgaattggtc attggtgttt gctcttgcct ctcctccatc ccctagaagt     4560

acacccccgt cttattaagg agcttttaaa gtttttctga atgtatagac atttctcggg     4620

ttcctacctt tgtctctgat ggaccatttt ccatttaaga cattttcctg tataagacag     4680

ttttatagct ggttcctttt agggtaaaga gtcttaagag agttttattg tgtctatggc     4740

aggtttggga aaggtaagaa atgggtcctt tttcctccta atgtttttgg cacttaaaac     4800

ataaaattca ttatcctatt aaaaaattaa attcagcttt gctaatccag aaattgttcc     4860

caaatgaaaa cttgttttaa gtccacccct tagtttcctt attttacaag gtctctcttc     4920

agggaccaac aggggcttag agagccttag ttagattaaa gggagaccct acctcttaaa     4980

accagttttc atttatgcaa acaaggacaa ttaagggaac cctgacccca caggctctca     5040

agtcttccca aggccagaat cgaaagaaaa ttaaaatttg aatgctgaat attctggctc     5100

tactctggcc ttttttctgg ttcccttcca aaatgcacaa atcataccct tgtctgctcc     5160

aattcagtct ccaaacctgg tgcctgtgct cctggccccc ctagcatcat gctatcccag     5220

gagtatcagg accagacaca tccacagcca ggctcatggg tctcagacag caacttgagt     5280

taaagctgaa actcatcctt cttctctgtg ttttctggtt taaaagctgc acttatattt     5340

tagccttatt attttctgta gttccggaga gatggtgggt tgccattctg gtaggaaaat     5400

ctgagttttc ttatctttga cctagaagag attctttttg gaccaacctg cgaaattggt     5460

agttaggtct atggaaagtg gtaggatttt ttttttttta atcctgtgca aaggaaaaga     5520

ggtgctttgt gggaaatcac taatgagaag gctaacctgc agcaccagag aaacctttcc     5580

aagtgctagg caggagaact gaagaactct ttcagtgaag tgagtcagcc tagaagaggc     5640

aacccacagt cttgattttt gttgctgttt cctgacctgt tcttgcctgt cacctgggcc     5700

tacacaggtc ccaagccaac ggggctttca tacccaagga tctgtttcct tgctgaaaat     5760

gaaaccctat ctttcacttt acattccttt caatccaact gatcaaaact ggtacccaca     5820

cttgcccttt ctccctctct ccagcacact cccctctaag aaagtaaaag caaagctttc     5880

ttaatggcaa cactttgggc ctgttctgtt gctcctgcct tatttctctt tcaaccctgt     5940

acatgactcg tgttcaccat ccccttgatc agtgtccatc cgcgctaatt tgcatcatga     6000

actgaacagt gtgtgagtgg tcacctacta aacccagctc tgggggcaga gctgtcttcc     6060

ccatctctgg tgctcctaac acctgtgaga tggtcctgtc gagaggacta ggaaccgata     6120

ggaggagagt ccttctcggc agagctcact gcaaacaact ggaattgagg ttgcacactg     6180

tgatttttac accgaaaagc caaaaggagc tggccatcca gggcctaggg agaccagcct     6240

tcctcagcta tgcttgccga aaccagcatg atgcttcaaa gagccctgct ccacccctca     6300

tggcatggat ccttttcctg gtgtggactc tgaagggtca gtcttcgggg aagagaggtg     6360

gggtggggct actagcatcc caatttagaa aatagaggag tttgtagcca gcagcctgta     6420

aactggaaac actggtctca gccaacctcc tcagggcgcc ctggcttctc cccaaggaga     6480

tgaggagcgg tgatgccagc accgggatgc gcagagcact ggaagggctg gtgcagatct     6540

acttcccatg cagaagagaa gtcacatctt ccagggaatc gcaatgttgt ggcgtctgac     6600

ttgtatgtca catttgtgta aaatggtata ttctttaaaa tagtgttgat aactggaata     6660

ttgtatgtat gcttggagat gctttgtgtg aacctaagac tgtcactcaa cagatgttgg     6720

attggggaaa atccaaagca caacttcaaa ataaaataca tttttaggtt tcgatgctgc     6780

aaaaaaaaaa aaaaaaaaaa a                                               6801


<210>  1630
<211>  7689
<212>  DNA
<213>  homo sapiens

<400>  1630
acccgccccc accccctcca gcatctcggg ccagacagag aaaaccttgt tcaagtttgc       60

agcaagtact ttcccggtgc gcaaaactgg gcgactggga acgcgttgag acgttcctct      120

ttcccgcttc tccaccttta cgcctgaaag aagactccca aagattgctt tcttctggga      180

cgctgcttgg acgctaaccg cgttgattgg aacagatttt gtgtcttggc tggctttggg      240

tgaagaccgg ggagaaaagg ttgcgctgcg attctcaaga tctctggacc tggattatca      300

ttgcaaatcc attaaagaag gagaagcaag cggatttcag agaggttgtt cttcagaaaa      360

aaatggttat ttctttgaac tcatgcctga gctttatttg tttattgtta tgccactgga      420

ttgggacagc atcacctctg aatcttgaag accctaatgt gtgtagccac tgggaaagct      480

actcagtgac tgtgcaagag tcatacccac atccctttga tcaaatttac tacacgagct      540

gcactgacat tctaaactgg tttaaatgca cgcggcacag agtcagctat cggacagcct      600

atcgacatgg ggagaagact atgtataggc gcaagtctca gtgttgtcct ggattttatg      660

aaagcgggga aatgtgtgtc ccccactgtg ctgataaatg tgtccatggt cgctgtattg      720

ctccaaacac ctgtcagtgt gagcctggct ggggagggac caactgctcc agtgcctgcg      780

atggtgatca ctggggtccc cactgcacca gccggtgcca gtgcaaaaat ggggctctgt      840

gcaaccccat caccggggct tgccactgtg ctgcgggctt ccggggctgg cgctgcgagg      900

accgctgtga gcagggcacc tatggtaacg actgtcatca gagatgccag tgccagaatg      960

gagccacctg cgaccacgtc acgggggaat gccgctgccc accaggatac accggagcct     1020

tctgtgagga tctttgtcct cctggtaaac atggtccaca gtgtgagcag agatgccctt     1080

gtcaaaatgg aggagtgtgt catcacgtca ctggagaatg ctcttgccct tctggctgga     1140

tgggcacagt gtgtggtcag ccttgccccg agggtcgctt tggaaagaac tgttcccaag     1200

aatgccagtg ccataatgga gggacgtgtg atgctgccac aggccaatgt cattgcagtc     1260

caggatacac aggggaacgg tgccaggatg agtgtcctgt tgggacctat ggcgttctct     1320

gtgctgagac ctgccagtgt gtcaacggag ggaagtgtta ccacgtgagc ggcgcatgcc     1380

tctgtgaagc aggctttgct ggcgagcgct gcgaagcacg cctgtgtcct gaggggctct     1440

acggcatcaa atgtgacaaa cggtgtccct gccacctgga aaacactcat agctgtcacc     1500

ccatgtctgg agagtgtgcc tgcaagccgg gctggtcagg actctactgt aatgagacat     1560

gttctcctgg attctacggg gaagcttgcc agcagatctg cagctgccaa aatggggcag     1620

actgtgacag tgtgactgga aagtgcacct gtgccccagg attcaaagga attgactgct     1680

ctaccccatg ccctctggga acctatggga taaactgttc ctctcgctgt ggctgtaaaa     1740

atgatgcagt ctgctctcct gtggacgggt cttgtacttg caaggcaggc tggcacgggg     1800

tggactgctc catcagatgt cccagtggca catggggctt tggctgtaac ttaacatgcc     1860

agtgcctcaa cgggggagcc tgcaacaccc tggacgggac ctgcacgtgt gcacctggat     1920

ggcgcgggga gaaatgcgaa cttccctgcc aggatggcac gtacgggctg aactgtgctg     1980

agcgctgcga ctgcagccac gcagatggct gccaccctac cacgggccat tgccgctgcc     2040

tccccggatg gtcaggtgtc cactgtgaca gcgtgtgtgc tgagggacgc tggggcccca     2100

actgctccct gccctgctac tgtaaaaatg gggcttcatg ctcccctgat gatggcatct     2160

gcgagtgtgc accaggcttc cgaggcacca cttgtcagag gatctgctcc cctggttttt     2220

atgggcatcg ctgcagccag acatgcccac agtgcgttca cagcagcggg ccctgccacc     2280

acatcaccgg cctgtgtgac tgcttgcctg gcttcacagg cgccctctgc aatgaagtgt     2340

gtcccagtgg cagatttggg aaaaactgtg caggaatttg tacctgcacc aacaacggaa     2400

cctgtaaccc cattgacaga tcttgtcagt gttaccccgg ttggattggc agtgactgct     2460

ctcaaccatg tccacctgcc cactggggcc caaactgcat ccacacgtgc aactgccata     2520

atggagcttt ctgcagcgcc tacgatgggg aatgtaaatg cactcctggc tggacagggc     2580

tctactgcac tcagagatgt cctctagggt tttatggaaa agattgtgca ctgatatgcc     2640

aatgtcaaaa cggagctgac tgcgaccaca tttctgggca gtgtacttgc cgcactggat     2700

tcatgggacg gcactgtgag cagaagtgcc cttcaggaac atatggctat ggctgtcgcc     2760

agatatgtga ttgtctgaac aactccacct gcgaccacat cactgggacc tgttactgca     2820

gccccggatg gaagggagcg agatgtgatc aagctggtgt tatcatagtt ggaaatctga     2880

acagcttaag ccgaaccagt actgctctcc ctgctgattc ctaccagatc ggggccattg     2940

caggcatcat cattcttgtc ctagttgttc tcttcctact ggcattgttc attatttata     3000

gacacaagca gaagggaaag gaatcaagca tgccagcagt tacctacacc cctgctatga     3060

gggtcgtcaa tgcagattat accatttcag gaacccttcc tcacagcaat ggtggaaacg     3120

ctaatagcca ctacttcacc aatcccagtt accacacgct cacccagtgt gccacatccc     3180

ctcacgtcaa caacagggac aggatgactg tcacgaagtc aaaaaacaat caactgtttg     3240

tgaatcttaa aaatgtgaac cctgggaaga gaggccctgt gggggactgc actgggacat     3300

tgccggctga ctggaaacat ggcggctacc tcaacgagct cggtgctttt ggacttgaca     3360

gaagctatat gggaaaatcc ttaaaagacc tgggaaagaa ttctgaatat aattcaagta     3420

actgctccct aagcagttct gagaacccat atgccactat taaagaccca cctgtactta     3480

tcccgaaaag ctcagagtgt ggttatgtgg agatgaaatc gccggcacga agagattccc     3540

catatgcaga gatcaataac tcaacttcag ccaacaggaa tgtctatgaa gttgaaccta     3600

cagtgagtgt tgtccaagga gtattcagca ataatgggcg tctctcccag gatccatatg     3660

acctcccaaa gaacagtcac atcccttgtc attatgacct gctgccagtc cgagacagtt     3720

catcctcccc taagcaagag gacagtggtg gtagcagcag caacagcagc agcagcagtg     3780

aatgacacca aaggaccgct tggtagccac tggaaccctt tccagaactg ctgtttggtt     3840

cttctccatc ctcaattttg ccactttcat gtgaatgtta gtcaattcgg tgggcaattt     3900

ttggacatga accagaaagc tgaaagctga ggctgacacg gactgtaggt gctttttgtt     3960

caggtggatt cgaaggagtt agagatgtga tttcccattg ctgttagttt tagaactata     4020

cccgtgaagc atgacttatt gtaagatgtt ggctgaaagc atgaacttgc agaactccct     4080

cggagacgca ggttgcagtg gacattggga ttgttgcttg aaaaattaaa atttgaatat     4140

tttctctctc atttgcatca tacagctcta cctaggattg tacagtttac cataaaattt     4200

acttcatgaa agtgggaatc actgaacatg tagaagacaa ggaacatatt gttaactcct     4260

gattcttaac tttattcaac tggactcaga attgtaggga taatatgaat gcaggaggaa     4320

acattctgtc aggcggtatg actggacaga ctttgaatat actctaaaag tggacagaaa     4380

atttacgaaa atcttagatt ttgtttagaa tgagaaaata tacaattaga attattttag     4440

aaatagtagg aagtattgca gaagtcaata cacaaatgtg ccaggcagag gtggttttct     4500

ctgtttgact ctcaaccaac ttcagatcta tgacattatt ctgatcactg gctccatcat     4560

acatattcac cacttgagat tcataacata tcaatagtta tttcataaat atagaaatga     4620

aataatttta tttttgacag actggatgga atgagtgtgt aatgattgat aaaggttgta     4680

aattttaaat gcaagatgac gcttacgttc tgtaaaccat tagtaataca tgctgtaata     4740

tagaattagt ggaacatttt gattaatctt tccctagaag tgactgaaat atttttgtgc     4800

atatttgaga aagggaactt tccttttatt aattgtcaat ttagagaaac tatgcttaag     4860

ctggtctttt gcattgctaa tgtgacatgt acccaacttt tcattaattt gtatttccat     4920

ttttaaattg catattctat gttttgtagt gtttggattg ttaatgaaaa aatattatat     4980

gttcgttatt ccttgtatta ttgccactta tcttttgctt gataaaaatg cgttgttctt     5040

ttttcttttg gagggacaag atgaaaatat ataatttgaa ttgattaaaa ttggtcgtta     5100

ctaaaatagt atagtaacca caagtgattg gcttataaat gaagtagaaa tgctttttaa     5160

tattccaaaa tagagttcct tttgatctgt tggtgctgag ccttggttaa accagggaga     5220

aggggagcag aaaggaaacg ttgttactga tgagtaccac agactcatct taaaaaaaac     5280

tctcattatg gtgatcatag aattgaccat ccaaactggg acactcttga gagtaaatgg     5340

agggcattat taataattat cttgtaatga acttaaatct ggactgttcc aggcaaacca     5400

gacttatctt gcaatatgag aatgctgaca caatgcagga aagccagttt cccttttgtt     5460

gatctacttg accaagcaaa ggggctgaaa aactgaataa ggaaacaact ttataagaga     5520

aacagtggtc ttcaatcttt taaagacatg aaatcctata tggcattctg tctcagtgag     5580

tcagttaaca aatacgtatg tgcaaccctt ctgctagtag tgcacataag tgattatccc     5640

tgccaggtat cgagttggaa tatccagtta tttcatgtca cacatcggca cgtatgatgg     5700

tggtttggtc agatggataa tacagcagac acacttagaa cactcactgc actggtggct     5760

gttcattttg aggaactcca aagtcaattc aaggaaataa ggaatgacct ggaacaggcc     5820

ttagaaacaa ttgatttatt ccaatagtta accactggct ggctcccaac tctaggtgat     5880

aggcatctaa ttgagacatg tgtgagtcaa tagccatcgg ggtccttttt ggtgagaaga     5940

aataagacat tttctccctt ttaaagatca tctcttcaga gctgcatggt aaatttgaat     6000

ttccccattg ttctctagag ctaggtcaaa aaaacaactg tttcttttct tattccacta     6060

ttaataaatt gaaagcttgc tgtacaaagg caacagcaac ttaaaaaaga aaatctggac     6120

aatagatgtg gactccaagg ggccactgcc atcccttcct gtgtgctctt tttgacaagt     6180

aaatcactcc agttagctga tgtcctgaaa tgacatttgt acctgaggca attcttatta     6240

gagcttactc aggacttttc aaacatcagg acacacatag caatttggat gttgtaaaac     6300

tacgtgttac atttggagag gtcttgttga gaaggcaaaa ttttctaaat attttgatat     6360

caatttgggt aaagaaagga atacttttgt tagaatgaga attaaagaga aaacaaaaga     6420

atcttggcaa aattttccct ctgaaattac aaactttagg aacttttcca gatgtatcga     6480

atttaatttg acattgatgt cactcttcat accaagtgaa tctattctca tgaactttga     6540

acccatgtta attttggacc ctataactaa tttcctttct gtatcccatg gtggtcaaag     6600

cagtaaagga gtttagagat acttagcaaa tgccattcat atagtattgt tagccaaact     6660

attattcctt ccttagaagt tgatgtatca gaaaatttat aagttatttg tatttatata     6720

taagtacatc agaacttgcc cacatgataa ctcatgtttg ctttaataag gaaaatatgt     6780

tatttgaggt taattatatg atagtgagga acattttaca attatttaca gtgtttgaca     6840

ttaattgctg tcctatgata cagtagtaat gttaacagag agtttaatat gtttagcatt     6900

atctttatgg aatttatatt caccaatttc aggaaaacca accatagaac tttataatag     6960

gacagttata acctgactga accaaatcca tcagcataat gactgtgtgt tctgagaaat     7020

gcaaacaact ttatgaaagt gtggtcatct tgacccccaa agagccacag tagctgtcaa     7080

ttattgagat ttttaaatgg taaatattgc aaaagttaaa caagggtacc acaatatcat     7140

ttataattga tgtcaatatt agtagtccac tttatgctta aaataaaatc ataaaaaatc     7200

aagttttaag gttatatttt ttaaaataat gaattttcta tctctaggca acatgtcttt     7260

attattcaag ctgaatgttt aagagagatt ttggtcttaa aggcttcaca tcatgaaagt     7320

gtacatgcat atgcaagtgt gaattacgtg gtatggatgt ttgcttgttt attaactaaa     7380

gatgtacagc aaactgcccg tttagagtcc tgttaatatt gatgtcctaa cactgggtct     7440

gcttatgcta gttcagtatt tggtctaggc ttcattttga tatgactgaa ttgcaatcta     7500

tatttttaaa aagaaaaatc aaaatacatt agggtttact tggttgtggc aaacaaacaa     7560

aaaatgcttt cagtgttgaa atatctctat tttccaaaga tgataaactt tcatcgttct     7620

tagcctacat tgtcatttat atcaccaaat gagtttatag attaatgcaa taaactttct     7680

aataaaaaa                                                             7689


<210>  1631
<211>  4523
<212>  DNA
<213>  homo sapiens

<400>  1631
gcagttcagc gagatgaaag ggataaagca gaacccgctg gcactaggaa aagcttccaa       60

cacacagtcc acaacacagc ttgggaacca aaaaagctac agatccagcc actcagccca      120

agcatgggag aactaccagc attgcctcat tgcaaaaaag aggaggaaaa caacgtgatc      180

catgtttaac aaaagagtct gtggactagg aggtgggagg gtaactacct gctgaaagtg      240

aactttcttt gatatccatg catatatata aactcagccc tgcctttgat gttcagcaac      300

tgattcactg atcagattac aggcatttca tctccctgct cgtctgcctt tgatctgcat      360

ggttaatttt attttcctgg atttgaagtt tcgtctgggc ttgtgctgac atacattttt      420

gggaaggtag aagcatttgg cacagaagtg ctgccaggag aaactaagtt gctgaacgga      480

actctccaac aataaataca tttgataaga aagatggctt taaaagtgct actagaacaa      540

gagaaaacgt ttttcactct tttagtatta ctaggctatt tgtcatgtaa agtgacttgt      600

gaatcaggag actgtagaca gcaagaattc agggatcggt ctggaaactg tgttccctgc      660

aaccagtgtg ggccaggcat ggagttgtct aaggaatgtg gcttcggcta tggggaggat      720

gcacagtgtg tgacgtgccg gctgcacagg ttcaaggagg actggggctt ccagaaatgc      780

aagccctgtc tggactgcgc agtggtgaac cgctttcaga aggcaaattg ttcagccacc      840

agtgatgcca tctgcgggga ctgcttgcca ggattttata ggaagacgaa acttgtcggc      900

tttcaagaca tggagtgtgt gccttgtgga gaccctcctc ctccttacga accgcactgt      960

gccagcaagg tcaacctcgt gaagatcgcg tccacggcct ccagcccacg ggacacggcg     1020

ctggctgccg ttatctgcag cgctctggcc accgtcctgc tggccctgct catcctctgt     1080

gtcatctatt gtaagagaca gtttatggag aagaaaccca gctggtctct gcggtcacag     1140

gacattcagt acaacggctc tgagctgtcg tgttttgaca gacctcagct ccacgaatat     1200

gcccacagag cctgctgcca gtgccgccgt gactcagtgc agacctgcgg gccggtgcgc     1260

ttgctcccat ccatgtgctg tgaggaggcc tgcagcccca acccggcgac tcttggttgt     1320

ggggtgcatt ctgcagccag tcttcaggca agaaacgcag gcccagccgg ggagatggtg     1380

ccgactttct tcggatccct cacgcagtcc atctgtggcg agttttcaga tgcctggcct     1440

ctgatgcaga atcccatggg tggtgacaac atctcttttt gtgactctta tcctgaactc     1500

actggagaag acattcattc tctcaatcca gaacttgaaa gctcaacgtc tttggattca     1560

aatagcagtc aagatttggt tggtggggct gttccagtcc agtctcattc tgaaaacttt     1620

acagcagcta ctgatttatc tagatataac aacacactgg tagaatcagc atcaactcag     1680

gatgcactaa ctatgagaag ccagctagat caggagagtg gtgctgtcat ccacccagcc     1740

actcagacgt ccctccagga agcttaaaga acctgcttct ttctgcagta gaagcgtgtg     1800

ctggaaccca aagagtactc ctttgttagg cttatggact gagcagtctg gaccttgcat     1860

ggcttctggg gcaaaaataa atctgaacca aactgacggc atttgaagcc tttcagccag     1920

ttgcttctga gccagaccag ctgtaagctg aaacctcaat gaataacaag aaaagactcc     1980

aggccgactc atgatactct gcatctttcc tacatgagaa gcttctctgc cacaaaagtg     2040

acttcaaaga cggatgggtt gagctggcag cctatgagat tgtggacata taacaagaaa     2100

cagaaatgcc ctcatgctta ttttcatggt gattgtggtt ttacaagact gaagacccag     2160

agtatacttt ttctttccag aaataatttc ataccgccta tgaaatatca gataaattac     2220

cttagctttt atgtagaatg ggttcaaaag tgagtgtttc tatttgagaa ggacactttt     2280

tcatcatcta aactgattcg cataggtggt tagaatggcc ctcatattgc ctgcctaaat     2340

cttgggttta ttagatgaag tttactgaat cagaggaatc agacagagga ggatagctct     2400

ttccagaatc cacacttctg acctcagcct cggtctcatg aacacccgct gatctcagga     2460

gaacacctgg gctagggaat gtggtcgaga aagggcagcc cattgcccag aattaacaca     2520

tattgtagag acttgtatgc aaaggttggc atatttatat gaaaattagt tgctatagaa     2580

acatttgttg catctgtccc tctgcctgag cttagaaggt tatagaaaaa gggtatttat     2640

aaacataaat gaccttttac ttgcattgta tcttatacta aaggctttag aaattacaac     2700

atatcaggtt cccctactac tgaagtagcc ttccgtgaga acacaccaca tgttaggact     2760

agaagaaaat gcacaatttg taggggtttg gatgaagcag ctgtaactgc cctagtgtag     2820

tttgaccagg acattgtcgt gctccttcca attgtgtaag attagttagc acatcatctc     2880

ctactttagc catccggtgt tggatttaag aggacggtgc ttctttctat taaagtgctc     2940

catcccctac catctacaca ttagcattgt ctctagagct aagacagaaa ttaaccccgt     3000

tcagtcacaa agcagggaat ggttcattta ctcttaatct ttatgccctg gagaagacct     3060

acttgaacag ggcatatttt ttagacttct gaacatcagt atgttcgagg gtactatgat     3120

attttggttt ggaattgccc tgcccaagtc actgtctttt aacttttaaa ctgaatatta     3180

aaatgtatct gtctttccta gtatgttttt atcttctcat gtattatcca tggttttctc     3240

tgtttgtgac agattagtaa aatttaatga gccctctttc ttgtggccgt ttctccatag     3300

ttttaggttt tgatatgtgt ttactagctt gcctgtgtct ggtacatctc atgacctcaa     3360

ttccctcacc tgaaatagga aatgagaatg tttcattgta gccccaagcg gtcatgtcaa     3420

cctagtgcct agtcataatt aattgacttt tcctgtatta cttctttttt taagtataaa     3480

ccaatgatcc tttggtagtc aagaactctt aggaacattg ccttttggac atgtaaaata     3540

tttaggattt gaccacacaa tggctatgaa aatgcaagta gtttcctcgc gtgacctcac     3600

catgattcac atacgtgcca ctgtttgaaa tctggtctgt ttgcatttct gttatgacag     3660

agagatgatg tttgcatttc tgttatgaca gagagatgat gaaagtaggc agggctgtgt     3720

tcctttgtgt agcctgtata tattttccat atgtagagcc ctgattaact tcaaggacaa     3780

acactggctg gagaaagcca gactgatggg aatgagactt tggccaaaaa tcccaaaaca     3840

tcattttcaa tcagtagaga agtgcttagg gttgaaaatt gatttcattt gctactgaat     3900

ttggtaaatc ctgggtaact tttatcaaga tgaagacatt ttaccctacc tactctagaa     3960

atatacaaca atgttatatt ttacactcct tggaaacatt tgaggaaaaa aatgcaattt     4020

gcacttcact ttgttggaat atcccatagc actcaataaa ctcagctgct agagtgccga     4080

tgtcaggagg gctgtgtcgg gtaatgcgtg tggctgaatg ggcataacca ctgtggcttc     4140

ttgtgctgca gaagctcgtt gacaagactg aggaggattt caagagcaac caagtaaagt     4200

catgaatttt ctaattttgt gtatatggaa tatattttta aatagagatt tttctacttt     4260

agataatgtg ttaatattgc tattacctag gttaagcact attgtctgtg ctagtaagaa     4320

aaagaaagga aaaccatcat tgctttatag tagcttatat caatttagat ttcatcatta     4380

ctattttgca tactggaatt tataaatgtg taaattatca ttttcttagt tttgtaatac     4440

cttttttatt tgtgaataaa attatcacct ggtattctta tttatgtgtt caaaaaaaaa     4500

aaaaaaaaaa aaaaaaaaaa aaa                                             4523


<210>  1632
<211>  7670
<212>  DNA
<213>  homo sapiens

<400>  1632
acacacacgc gccctcaccc gccaccgccg ccgcggccgc cgccgcaccc ggacagcgag       60

cggctgaggc cgccagggcc caaaggacag cggcccagac aggggctggc ggcccggccg      120

gccccggctc accgactcgg gcagcatcca cctgccccag ccaacaccct tctctcgccc      180

caggtccttt ctcagcctcc agctgggctg tccccaagct gagctgaggc tcttctcctc      240

cgatccccac ctctgcccgg acatccacca tggggacagc caccaggagg aagccacacc      300

tgctgctggt agctgctgtg gcccttgtct cctcttcagc ttggagttca gccctgggat      360

cccaaaccac cttcgggcct gtctttgaag accagcccct cagtgtgcta ttcccagagg      420

agtccacgga ggagcaggtg ttgctggcat gccgcgcccg ggccagccct ccagccacct      480

atcggtggaa gatgaatggt accgagatga agctggagcc aggttcccgt caccagctgg      540

tggggggcaa cctggtcatc atgaacccca ccaaggcaca ggatgccggg gtctaccagt      600

gcctggcctc caacccagtg ggcaccgttg tcagcaggga ggccatcctc cgcttcggct      660

ttctgcagga attctccaag gaggagcgag acccagtgaa agctcatgaa ggctgggggg      720

tgatgttgcc ctgtaaccca cctgcccact acccaggctt gtcctaccgc tggctcctca      780

acgagttccc caacttcatc ccgacggacg ggcgtcactt cgtgtcccag accacaggga      840

acctgtacat tgcccgaacc aatgcctcag acctgggcaa ctactcctgt ttggccacca      900

gccacatgga cttctccacc aagagcgtct tcagcaagtt tgctcagctc aacctggctg      960

ctgaagatac ccggctcttt gcacccagca tcaaggcccg gttcccagca gagacctatg     1020

cactggtggg gcagcaggtc accctggagt gcttcgcctt tgggaaccct gtcccccgga     1080

tcaagtggcg caaagtggac ggctccctgt ccccgcagtg gaccacagct gagcccaccc     1140

tgcagatccc cagcgtcagc tttgaggatg agggcaccta cgagtgtgag gcggagaact     1200

ccaagggccg agacaccgtg cagggccgca tcatcgtgca ggctcagcct gagtggctaa     1260

aagtgatctc ggacacagag gctgacattg gctccaacct gcgttggggc tgtgcagccg     1320

ccggcaagcc ccggcctaca gtgcgctggc tgcggaacgg ggagcctctg gcctcccaga     1380

accgggtgga ggtgttggct ggggacctgc ggttctccaa gctgagcctg gaagactcgg     1440

gcatgtacca gtgtgtggca gagaataagc acggtaccat ctacgccagc gccgagctag     1500

ccgtgcaagc actcgcccct gacttcaggc tgaatcccgt gaggcgtctg atccccgcgg     1560

cccgcggggg agagatcctt atcccctgcc agccccgggc agctccaaag gccgtggtgc     1620

tctggagcaa aggcacggag attttggtca acagcagcag agtgactgta actccagatg     1680

gcaccttgat cataagaaac atcagccggt cagatgaagg caaatacacc tgctttgctg     1740

agaacttcat gggcaaagcc aacagcactg gaatcctatc tgtgcgagat gcaaccaaaa     1800

tcactctagc cccctcaagt gccgacatca acttgggtga caacctgacc ctacagtgcc     1860

atgcctccca cgaccccacc atggacctca ccttcacctg gaccctggac gacttcccca     1920

tcgactttga taagcctgga gggcactacc ggagaactaa tgtgaaggag accattgggg     1980

atctgaccat cctgaacgcc cagctgcgcc atggggggaa gtacacgtgc atggcccaga     2040

cggtggtgga cagcgcgtcc aaggaggcca cagtcctggt ccgaggtccg ccaggtcccc     2100

caggaggtgt ggtggtgagg gacattggcg acaccaccat ccagctcagc tggagccgtg     2160

gcttcgacaa ccacagcccc atcgctaagt acaccctgca agctcgcact ccacctgcag     2220

ggaagtggaa gcaggttcgg accaatcctg caaacatcga gggcaatgcc gagactgcac     2280

aggtgctggg cctcaccccc tggatggact atgagttccg ggtcatagcc agcaacattc     2340

tgggcactgg ggagcctagt gggccctcca gcaaaatccg gaccagggaa gcagccccct     2400

cggtggcacc ctcaggactc agcggaggag gtggagcccc cggagagctc atcgtcaact     2460

ggacgcccat gtcacgggag taccagaacg gagacggctt cggctacctg ctgtccttcc     2520

gcaggcaggg cagcactcac tggcagaccg cccgggtgcc tggcgccgat gcccagtact     2580

ttgtctacag caacgagagc gtccggccct acacgccctt tgaggtcaag atccgcagct     2640

acaaccgccg cggggatggg cccgagagcc tcactgcact cgtgtactca gctgaggaag     2700

agcccagggt ggcccctacc aaggtgtggg ccaaaggggt ctcatcctca gagatgaacg     2760

tgacctggga acccgtgcag caggacatga atggtatcct cctggggtat gagatccgct     2820

actggaaagc tggggacaaa gaagcagctg cggaccgagt gaggacagca gggctggaca     2880

ccagtgcccg agtcagcggc ctgcatccca acaccaagta ccatgtgacc gtgagggcct     2940

acaaccgggc tggcactggg cctgccagcc cttctgccaa cgccacgacc atgaagcccc     3000

ctccgcggcg acctcctggc aacatctcct ggactttctc aagctctagt cttagcatta     3060

agtgggaccc tgtggtccct ttccgaaatg agtctgcagt caccggctat aagatgctgt     3120

accagaatga cttacacctg actcccacgc tccacctcac cggcaagaac tggatagaaa     3180

tcccagtgcc tgaagacatt ggccatgccc tggtacaaat tcggaccaca gggcccggag     3240

gggatgggat ccctgcagaa gtccacatcg tgaggaatgg aggcacaagc atgatggtgg     3300

agaacatggc agtccgccca gcaccacacc ctggcaccgt catttcccac tccgtggcga     3360

tgctgatcct cataggctcc ctggagctct gatcctggaa cccctccctc tgcgccgcag     3420

ctggacgcca cctccgacgg acacagccag ccccttcctg ctgccaaggt ggcctgacac     3480

tgtgccagag agtggctggt tttaaatacc tactttaaac agtgcccttt ttgtaggagg     3540

taggatattt tatattctgc cgcaggatag aacccacgca aggattttct ttaaattgag     3600

aggcaccagg cagtaacttc catgatgaca ctgacgccta tacctgagct ctaggctgcc     3660

tggagggaag gaacaggccc atgggaagaa gggggtttta aaaacatgtc ttcaactcag     3720

cagagatggc cctctgggac cctatacgga ctccgccact tgagagcagt cctaggcccg     3780

gcaggaacac cagacatgaa caggttgaag aactggagcg aagtgcacac ctcaccatcc     3840

ttcagtctaa ggaagaaggg caagccctgg gaccaagagc tctcccgcct tctccctcga     3900

gcagcagcaa ggaccctgac gctgtccccg ataactccct aggggctcct gcctgcccaa     3960

gcggctgaga accagcgccc cgatgcctga ggctgggagc ctgagcccct tcagctttga     4020

ggggggtgat actccaggct gtttggggtg ggagccaaaa agagttgaga ggccagggcc     4080

cttggtggaa aggggcacca gccttggtct gagatagtca caacccaggt gacgatgccc     4140

tctcagccaa cactgccaac ctgaccctgt catcccgatt gacagcgcca cttcaggtgg     4200

ctgggtgact aaagggcttg tcttggtggg gtctcccacc cctccaagac ccattctgca     4260

cagtccctcc agggtttggg caggagatgg ccaatcatgc gcccacctct ccagtgctgc     4320

ctgcagtcag ctcggcctcc ccgacctgca gccccagact ctgctctccc agcactgact     4380

cactcctgcc tgggagggga atgcagcatt catgctgtgt gtcctggtat tgggaggttt     4440

ctgggaaggg cagaggataa atgtggccct gcctgctccc aggtatacct aggaccacct     4500

ggccagatcc gctcccagac ggccttggac tgcttgcatt tccccggaga aaaaggggtt     4560

aataaatggg ccatcctttc ctgagctctg ggtatactac cagtcacaga acgtcagagc     4620

tggaagaagc cttagagctc aacttcttca agcccctcac tttacagatg aggaaatgga     4680

ggtggtccag agagggtctg ggattcccaa ggtcacacag cccagaagag atggggctgg     4740

gttaagaact cgagtcttcc acctttctgt tcaaggctgt ttgtctaccc agaggaagga     4800

ggcactgctg aatggctatg gcctggctaa gaaggtgatt agtcagtagg gtgtgaaaat     4860

tctacttcaa ggggttcgga ttggtgatca tggggattgg catggctggg ttcccgtcca     4920

aggtgtgggc agagcttcta ccaaacttca acatggaggg ctgacttgaa gctccctgtc     4980

cccctcactc ttgccccaag aaaagaggcc aaagcaagag cagattccct aggcaagagc     5040

agcagcacaa ctaggaaacc ccaaagccca tgctccgaca ggtggccctt cacagggggc     5100

agcgggacag gcatcttgaa gggcatatgt cctcggaagc tccgagcctg ttttctgtag     5160

tttatagtta gagctctatt ttgttatggt tttttaaact tttaagtcct gctctatttt     5220

cctgggcagg tttatgttga tgtttaccca ctacaatttt ttaaaaatat aagctcacat     5280

gccttttccc tgccacagcc aaacccccac tgcaccctac ccacccaccc ctagcccagg     5340

tcagctttcc tggagctggc taatgaaagc ctcctcacct cttcccaacc cttacaagca     5400

agggtgctag gggctcagct atacgaccat tctccctgac agggagtcca aacttggcct     5460

agcatccctc ctggcccccc tctggccacg acttggcctg tgcctggttc tctatcagaa     5520

aggggatgct gaacaaaacc tccttccaag ttttatccaa ttcgttcctc attgcctcgg     5580

gctgcgtcag gggaagcagg ggacaggtgt ccagttgctg ggccgaggga ggagctggtt     5640

tggcatagga cctaaccagt gaagctagag gctacagcca ctaaacttgc ttcaggccaa     5700

cgatagttac tcacaagtaa gtaccttaat gctaatgagg tccactaaaa aggggaggaa     5760

ggcagacctc ctgggagacc cacgaagggt ttttagccag ggaaaactga gccccaggaa     5820

aacctaacca ctgggcaggc agaatttgtt tgagggatag aacgacaaca aaataaatgt     5880

tcctgcagcc tgagatttca ggtagagtac tgactaaggt ttaataagac aataggtgac     5940

ctgaggacat gcaagcttgt aaaatgcaac agcctcctgc tagagtgact tgtacatgag     6000

cttgcttgca gaagactaga ttagatgttt ctcaggatcc cctcctgcgc aggggttctc     6060

tgattttcgt gttctctgcc cagatgggct gggggagttg agagtgtgct tattttcact     6120

gcgatcatga gaccacagtt ctgggttatc tcctctcata catcaagccc cagaggaggc     6180

ggcaagagga acagccacaa acaagtactt taccccacag cttagtggcc agtaaacacc     6240

ctggggacta ggaaaaggaa ccaactgtag gcacctctcc agggcctagg gagacaagtg     6300

tcctctcttc tgcatacatt tgggctcccc ttacagagcc ctttgccctg gctctctggt     6360

ccttgttgct ctaacagtcc agatgtacac ccagcctcag ggggaaggca gctctctcca     6420

gacagagtct cagggcccag caaggtcagg ttatctgctt tcattcaggg caacaaatga     6480

tacaaatggt gccagggagt ggcaaggcca tgggggtagg tgggggtgtc tttttctttt     6540

cataaagtaa caacagacga gactgaggtt aaacatcaga aaaaaacctc tggaatgacc     6600

ttcctcattc caggaggccc tggaataagg aagaggcttc tttctgaggg agctttgagg     6660

aattttgaca gctgttgaca tgggatttgg gaaaggtgaa gctgtgactg gaggggcagg     6720

agatggtcca agtgtccatc cagagatgag actcttagaa tcaaagtgtt cagcccagga     6780

agtcttggag atcccacctt ctgtggccct gcaccttatg ggaagccatt aagggggctc     6840

atctaggaat tctggttaca gcccagtgct catcccagcg tatgctgcct ctttagggca     6900

gccccaaggg ccagccagcc tgtactctgg gcaagagccc aaaatggcta ggaatgtttg     6960

actcccttaa tctcttcccc agctacagag gaatcttttc tctgcctggt ctcagaatgg     7020

gactgccaac tggctcattg gtgggagaca cagtatcctc aaacctgtgg ccactggcat     7080

gacagtggtg ctctgtctcc ctgggtgaca cccaccctag gcttcctcct ggatgtgatg     7140

gggattgcca gagaggctct tagcataaaa ggcattaggt gggcattttt ctgtgtgccc     7200

ccaaaaagct ccatggaaac aggcacctgg tagctgcgga acacccgtgg acttgtgtat     7260

atggtcatag gctttgggaa gacaggacgt aaaggaaaat gagagaaaca aaatgggtca     7320

gatagctttg gccacagccc caggcagcct ttggggccta tgacacttag tgcccttaga     7380

tgggatacat cttgcctcgg ccccaagact cctccaactt acccgtccca tccagggcct     7440

gcacagctta gagaggctca cagcttggca aatgctaggg cttcatcaga ccactgactt     7500

gactcagtgt ttgttaaaat ggaaccactc ccgttggcct actgtttctc tcctgtactt     7560

cttgtaatga tagttattta ttgactctgg tagcaggcag ttcttaaata aagatggttt     7620

ctcaacctgt tggggaagct ggcacgagct gtgggtgtta tcatcaggct                7670


<210>  1633
<211>  2003
<212>  DNA
<213>  homo sapiens

<400>  1633
gccggggtct aggcaccacg gtggctggcg gcctgcgggc ggcgctgtgg cccgtcgggc       60

ggctccacag agccgcccta gccttccgcc ttccccaagc caacgtctcc gccgtcggct      120

ccgcggcgcc gccatggccg acgtggaaga cggagaggaa acctgcgccc tggcctctca      180

ctccgggagc tcaggctcca agtcgggagg cgacaagatg ttctccctca agaagtggaa      240

cgcggtggcc atgtggagct gggacgtgga gtgcgatacg tgcgccatct gcagggtcca      300

gatgcctgtc ttagatgtca agctgaaaac aaacaagagg actgtgttgt ggtctgggga      360

gaatgtaatc attccttcca caactgctgc atgtccctgt gggtgaaaca gaacaatcgc      420

tgccctctct gccagcagga ctgggtggtc caaagaatcg gcaaatgaga gtggttagaa      480

ggcttcttag cgcagttgtt cagagccctg gtggatcttg taatccagtg ccctacaaag      540

gctagaacac tacaggggat gaattcttca aataggagcc gatggatctg tggtcctttg      600

ggactcatca aagccttggt ttagcatttt gtcagtttta tcttcagaaa ttctctgcga      660

ttaagaagat aatttattaa aggtggtcct tcctacctct gtggtgtgtg tcgcgcacac      720

agcttagaag tgctataaaa aaggaaagag ctccaaattg aatcaccttt ataatttacc      780

catttctata caacaggcag tggaagcagt ttcagagaac tttttgcatg cttatggttg      840

atcagttaaa aaagaatgtt acagtaacaa ataaagtgca gtttaaaacc caactcttac      900

tcttaatttg ttcctaatac gtatttttgg cagggagagg gaacggtcca tgaaatcttt      960

atgtgatata aggattttaa gtttgggcca gtgaacaggg taaataaaat ttaacttttg     1020

agcatatgga attttgattg cctttaaagt tactattctg tatcattgat tcatcaagaa     1080

aacctagatc tgcactcacc tcactgttca atcattgagt ggtaaaggac agaagtattt     1140

tctagttctg gtcagatgat ataatttttt tttttttttt ttgtgggggt gaagtcttgc     1200

tctgccaccc aggctggagt gcagtggcat gatgtcaact cactgcaacc tccgcctccc     1260

gggttcaagt gattctcctg cctcagcctc ccgagtagct gggattacag gtgtgtgcca     1320

ccacacccgg ctaatttttg tatttttagt agagacggga tttccccatg ttggccaggc     1380

tggtctcaaa ctcctgacct caggtgattc gcccacctca gcctcccaaa gtgctgggat     1440

tacaggtgtg ggccactgca cctggcccag atgatataat ttaactgtgt tttaggtaac     1500

atgttaatga gggaaaatgt ttaccagtgt agcattggat caaaaagttt atcacacagt     1560

gttttaataa atggtttatt ctgcttacct tatttgaatt gtcattataa ttttatatgc     1620

aaccttaatt tgtcaagtaa atactttcat ttaatttgaa agaattcata ttcatttgct     1680

ctttcatttg acaataataa aatttaaggt ttattacctg gaaagagtgc aagaaaatac     1740

taaacaactt tatcaaactg attcacactg aggggaggtt attttgtaac aaataatgga     1800

ccacaagttc attttgtatt cttctgtagt agaggctact gatatgaatt taagaaaaaa     1860

ccttagaatc ttaacttttc acatctgcag atgcagtgtg ccattctgaa tttttcaatc     1920

taagggatgt ggatacatag aatgtttaaa aagataacaa ttagaatgaa aaattaaaat     1980

tatgtatgct tttaaaaaaa aaa                                             2003


<210>  1634
<211>  2766
<212>  DNA
<213>  homo sapiens

<400>  1634
agaaggcgcg atgttgacgg ggtcctaaga tggctgctgg gcgaccactt cctgacagct       60

ccagttaatg ggactgccag caggctagac atccttcgcc ggaatgtgca gcgcttagtt      120

ctgtgcccgg gaggggcttc tctctctttt gggattggag tgtggcattg ccgccagaaa      180

gcctgcagaa ttccgggttg tgcagccaag caggaacggt gtacctttct agacccatcc      240

tcttgcaatc ttggacccta agaaaagatg tggagtgggc tgctacctcc tggcctaaat      300

gaaagtgacg ctgagtcaaa ctcggaagat gaagctacgt tggagaactc tggacttaac      360

ttacaggaag ataaagagga tgagagcatc agaaaaacag aaatcataga tttctcaaca      420

gatgaaccaa aaactgaaac agagtcaaat gtaaatgcct atgaagagtg tccttctgga      480

attcccatag atatgtggaa taaatttcaa gaattgcata aaaaacattc tgaacagaaa      540

agcacaacct caagattcag agggaaaaga agaaaacgct ccagaaaaga taaattgaag      600

aatgaaaaag aattacatag tgaaccgtcc tcaaatgaaa cccagtggaa agagcttact      660

cagtattttg gagtcaatga tagatttgac ccgcctgtta aaaggaaaaa agttgagaag      720

tcaggccttg aaaagaggat agaccaggct gtggaggagt ggaatattga gaaggctgag      780

gaactcagca accagctagc tactcgagag cttggtgtaa aaattgccaa agcagttgcc      840

tgccacaact ttgtaaaagc caaaaaggag gttgaaaatt cacaggctgc ccgaaaaaag      900

aagaaacttg catgggggtt tgaagcaaag aagagatggg aaaccaaaag caacatggga      960

tacatgtaac ttgccagagt gcttcaagac atttgtagac tcaaatgctc aatttactga     1020

gaatgttttc ctgcctatgt taatatgtca gaaaattgat agcactaaaa caaaaataag     1080

cataaaattt gggattttga ttatcagctc ttttcagtct ttctttaagg actttgtcct     1140

attgaagtga ataaaatgaa gcattctgtt atttgtataa gaaatgtaag aaaaaaaata     1200

tagaaagaag aggataggat tttgtttatt tgtatggatg gacccttggt ataaaatcac     1260

ttttggcgct ttccattcat ttggtttagc acagccagtg agcttctcgt actttctttc     1320

tttttttttt tttttttgag acagagcctc gcttgctctg tcacccaggc tagagtgcag     1380

tagcacgatc ttggctcact gcaaccactg cttcctgggt tcaagtgatt ctcatgcctc     1440

agcctcctga gtagctggga ttatggacaa atgccaccac acccggctaa tttttttttt     1500

ttttttgtat ttttagtaga gacagagttt tgctgtgttg gtcaggctgg tcttgaactc     1560

ctggcctcat atgattcacc tgcctctgcc tcccaaagtt ctgggagtac agacatgagc     1620

taccatgctg cccttgtatt ttcttatctg tacccagtgt aactacacgt ttactggaac     1680

tgtgttttta agactgacag ttgtttataa tggattagtc gtaagtacca aaaagtctca     1740

gttgatatta tctttacaaa tgacttgacc ttaatgttat aaaagtagtt actgtttttt     1800

tttaattgga ggcagacttg atatttcaga gttgcatagt aaaagcaatt tgttaatttt     1860

tgtgtacttt cagataaact attacaataa agaaaggagc agaatgtagt atttggaaga     1920

tgatttaaat tcagcaacgc ctaaaaatgt cttcctaagt atttttctca gccatgtcat     1980

tctttaaatt atgagatggt tcttagaaga gaaaatggtg taattgtatt aaacagacaa     2040

ttataactca agataatata actttgaacc ttctaagaac tgatttgttt ggttttcctc     2100

ccattcccca ttcctcctta aaagattgaa tgaattaatg agcagaaaga gaggattggt     2160

aacatgggaa atcgttttca ttagatgtac atttcctggt tctgacagga aaggggctcc     2220

agaaaatcat aaaacaagca ggtgaacaag accaggtgtg tcggcacctc cctgctcagt     2280

gcccagcgga ggtaaagaac cactcagcat ggtttttgtc agttcacctc ttctgtcgtt     2340

gtcagaggtt tcctacctgt ctgatataaa ctttctctgg gttgataata taaattcaga     2400

aacatgtaaa atgaatcatg attatattac tgttattttt agacttaaaa tagtaacaaa     2460

attttattta tggtggcaca tttaatggct ttttttttct gtgttctgga ataagagaat     2520

acctagctac tatttaagca tccaaaaatc atatcttgct ttcatttagt tgagaaaagc     2580

cagcatagag aaagcaaagt tttagaatat tatgtgtcat actaattcag tatccagacc     2640

aaatgttgga aagtcttatt ttatgattta atatcccttg ttccatttta cagatatgat     2700

catgtaaaac ttacctacaa tattcatttc aaactgctaa attaggtaaa tacagacttt     2760

tagtat                                                                2766


<210>  1635
<211>  2565
<212>  DNA
<213>  homo sapiens

<400>  1635
agaaggcgcg atgttgacgg ggtcctaaga tggctgctgg gcgaccactt cctgacagaa       60

gaaaagatgt ggagtgggct gctacctcct ggcctaaatg aaagtgacgc tgagtcaaac      120

tcggaagatg aagctacgtt ggagaactct ggacttaact tacaggaaga taaagaggat      180

gagagcatca gaaaaacaga aatcatagat ttctcaacag atgaaccaaa aactgaaaca      240

gagtcaaatg taaatgccta tgaagagtgt ccttctggaa ttcccataga tatgtggaat      300

aaatttcaag aattgcataa aaaacattct gaacagaaaa gcacaacctc aagattcaga      360

gggaaaagaa gaaaacgctc cagaaaagat aaattgaaga atgaaaaaga attacatagt      420

gaaccgtcct caaatgaaac ccagtggaaa gagcttactc agtattttgg agtcaatgat      480

agatttgacc cgcctgttaa aaggaaaaaa gttgagaagt caggccttga aaagaggata      540

gaccaggctg tggaggagtg gaatattgag aaggctgagg aactcagcaa ccagctagct      600

actcgagagc ttggtgtaaa aattgccaaa gcagttgcct gccacaactt tgtaaaagcc      660

aaaaaggagg ttgaaaattc acaggctgcc cgaaaaaaga agaaacttgc atgggggttt      720

gaagcaaaga agagatggga aaccaaaagc aacatgggat acatgtaact tgccagagtg      780

cttcaagaca tttgtagact caaatgctca atttactgag aatgttttcc tgcctatgtt      840

aatatgtcag aaaattgata gcactaaaac aaaaataagc ataaaatttg ggattttgat      900

tatcagctct tttcagtctt tctttaagga ctttgtccta ttgaagtgaa taaaatgaag      960

cattctgtta tttgtataag aaatgtaaga aaaaaaatat agaaagaaga ggataggatt     1020

ttgtttattt gtatggatgg acccttggta taaaatcact tttggcgctt tccattcatt     1080

tggtttagca cagccagtga gcttctcgta ctttctttct tttttttttt ttttttgaga     1140

cagagcctcg cttgctctgt cacccaggct agagtgcagt agcacgatct tggctcactg     1200

caaccactgc ttcctgggtt caagtgattc tcatgcctca gcctcctgag tagctgggat     1260

tatggacaaa tgccaccaca cccggctaat tttttttttt tttttgtatt tttagtagag     1320

acagagtttt gctgtgttgg tcaggctggt cttgaactcc tggcctcata tgattcacct     1380

gcctctgcct cccaaagttc tgggagtaca gacatgagct accatgctgc ccttgtattt     1440

tcttatctgt acccagtgta actacacgtt tactggaact gtgtttttaa gactgacagt     1500

tgtttataat ggattagtcg taagtaccaa aaagtctcag ttgatattat ctttacaaat     1560

gacttgacct taatgttata aaagtagtta ctgttttttt ttaattggag gcagacttga     1620

tatttcagag ttgcatagta aaagcaattt gttaattttt gtgtactttc agataaacta     1680

ttacaataaa gaaaggagca gaatgtagta tttggaagat gatttaaatt cagcaacgcc     1740

taaaaatgtc ttcctaagta tttttctcag ccatgtcatt ctttaaatta tgagatggtt     1800

cttagaagag aaaatggtgt aattgtatta aacagacaat tataactcaa gataatataa     1860

ctttgaacct tctaagaact gatttgtttg gttttcctcc cattccccat tcctccttaa     1920

aagattgaat gaattaatga gcagaaagag aggattggta acatgggaaa tcgttttcat     1980

tagatgtaca tttcctggtt ctgacaggaa aggggctcca gaaaatcata aaacaagcag     2040

gtgaacaaga ccaggtgtgt cggcacctcc ctgctcagtg cccagcggag gtaaagaacc     2100

actcagcatg gtttttgtca gttcacctct tctgtcgttg tcagaggttt cctacctgtc     2160

tgatataaac tttctctggg ttgataatat aaattcagaa acatgtaaaa tgaatcatga     2220

ttatattact gttattttta gacttaaaat agtaacaaaa ttttatttat ggtggcacat     2280

ttaatggctt tttttttctg tgttctggaa taagagaata cctagctact atttaagcat     2340

ccaaaaatca tatcttgctt tcatttagtt gagaaaagcc agcatagaga aagcaaagtt     2400

ttagaatatt atgtgtcata ctaattcagt atccagacca aatgttggaa agtcttattt     2460

tatgatttaa tatcccttgt tccattttac agatatgatc atgtaaaact tacctacaat     2520

attcatttca aactgctaaa ttaggtaaat acagactttt agtat                     2565


<210>  1636
<211>  8753
<212>  DNA
<213>  homo sapiens

<400>  1636
cttcccgcac tgcttgggga gagctggtga gcaagagtct ggcccgagtt agctagagct       60

gttgccatga caagcatttt cttaagaaag ctctgctgtt gagatcgtcc aaagctgggg      120

gctgggaggg ggggcacgaa cttcgtgggg caccatccct ccgaagagag caagatcaga      180

gacacccgcc cagctctcct gcaccctttt tctttcagga acctgagagg tccttcccat      240

tggaggggca gggggaggag acccagccca ctccccggcc ttagccagaa aggcaagaga      300

gcaaagccag cgtctctagc ttggttgcca cactggggag actggtgggt ggtcacccca      360

ccctaccctc atccatggaa acccggaggg agagtcccgc ctgaagaaac ctggatcttt      420

gctagaaaga gagagatcca gttgtcatcg gtatccagga agctctcctc ttcctcctcc      480

tgacgtctac tactacagtt gctggttgtt gctaaggttg ctgccatggt aacatgcaca      540

tcctgtttac accttcatct gggcaagttg gtctaagcta ggaacctacc taccctggac      600

aactactatc atcaccacct ggggacacca atcatcgtga cacggagtcc accttccact      660

cagttccccc atcctcttcc tcctctcgct gccagacttc atacggaaga aaggatctag      720

acttcggacg gctactcggg agcttattgc acaagatata ttcaatctat tccctcactg      780

ggcccccaga gaagcaagaa gtaggaagaa gttgagacag ggaggcagga gacactggtc      840

agttgaaggg aaacgctaca tcttctctgg ttgaggggct tggtaacagc aggcaaaatg      900

acgaacccat cagaccgtgt cttgcctgcc aactcgatgg ccgagagccg tgaaggggac      960

tttggctgca cagtaatgga actgaggaag ctcatggagc tgcgttcaag ggatgcactg     1020

acccagatta atgtccacta tggaggtgta cagaatctct gcagtagact gaaaacctcc     1080

cctgtggaag gtctgtctgg gaaccctgca gatctggaga aacgtaggca ggtgtttgga     1140

cacaacgtga tcccccccaa aaagcccaag actttcttag aattagtgtg ggaagctctt     1200

caagatgtca cgcttatcat cctggagatt gcagccatca tctccctggt cctgtccttt     1260

tatcgccctg ctggtgaaga aaatgaactg tgtggtcaag tcgcaactac cccagaagat     1320

gaaaatgagg cacaagctgg ctggattgag ggggcagcca tccttttctc agtgatcatc     1380

gtggtgttag tgactgcctt taatgattgg agcaaagaga agcaattccg ggggctgcag     1440

tgccgcattg aacaggagca aaagttctcc atcatccgaa acggtcaact catccagctc     1500

cctgtggctg agattgtggt tggtgatatt gcccaagtca aatacggtga tctgctgcct     1560

gcagatggaa tcctgatcca agggaatgat ctgaagattg atgagagctc tctgacaggg     1620

gaatctgacc atgtcaagaa gtccctggac aaagacccca tgttgctctc agggacccat     1680

gtcatggaag gttctggccg gatggtggtg acagctgttg gtgtcaactc tcagactgga     1740

atcatcctta ctctcttggg ggtcaatgag gatgacgaag gggagaaaaa gaagaaaggt     1800

aaaaaacaag gagtccctga aaatcgcaac aaagcaaaga cccaagacgg agtggccctg     1860

gaaatccagc cactcaacag ccaggaggga atcgacaatg aggaaaagga caagaaggca     1920

gtcaaggtgc ctaaaaagga gaagtcagtg ctgcagggca agctgactcg cctggctgtt     1980

cagattggga aagccggtct gctcatgtct gctctcacgg ttttcatcct gattctatac     2040

tttgtgattg acaactttgt gataaatcgc agaccatggc tccctgagtg tactcccatc     2100

tacatccagt actttgtcaa gttcttcatc atcggcatca ctgtactggt ggtggctgtg     2160

ccagaggggc tgcctctggc tgtcaccatc tcactggcct actctgtgaa gaaaatgatg     2220

aaagacaata acctagtacg gcacttggat gcttgtgaga ccatgggcaa cgccaccgcc     2280

atctgctctg ataagacagg cacgttgacc atgaaccgca tgactgtggt acaagcttat     2340

attgggggca tccattaccg tcaaatccca agccctgatg tcttcctgcc caaagtcctg     2400

gacctcattg tcaatggcat ttctatcaac agtgcttata cctccaagat tctgcctcca     2460

gagaaggagg gaggcctgcc tcggcaggtg ggcaacaaga ccgagtgtgc tctgctaggc     2520

tttgtcacag atctgaagca ggattatcag gctgtgcgta atgaagtgcc cgaggagaag     2580

ctctacaagg tgtacacctt taactcagtg cgcaagtcaa tgagcaccgt catcaggaat     2640

cccaacggtg gcttccgtat gtacagcaag ggcgcctctg agatcatctt gcgcaagtgt     2700

aatcgaatcc tggaccggaa aggggaagca gtgccattca agaataaaga cagagatgat     2760

atggtacgca ctgtcatcga gcccatggcc tgtgatggac tccggactat ctgcatagct     2820

taccgggact tcgatgacac agagccctct tgggacaatg agaatgagat cctcaccgaa     2880

ctgacctgta tcgcggtggt gggcattgag gaccctgtgc gcccagaggt gccagatgct     2940

attgccaaat gcaaacaagc tggcattact gtcagaatgg tgacaggtga caacatcaac     3000

acagcccggg ccattgccac caaatgtggc attctgacac ctggggatga cttcctgtgc     3060

ttagaaggca aagaattcaa ccggctcatc cgcaacgaga aaggcgaggt agagcaagaa     3120

aagctggaca agatctggcc taagcttcgg gtcctggcgc gatcttctcc cactgacaag     3180

cacaccctgg tgaaaggcat aattgacagc actgttgggg aacaccggca ggtcgtggct     3240

gtcactggtg atggcacaaa tgacgggcct gctctgaaga aagcggatgt tggttttgcc     3300

atgggcatcg caggcacaga tgtagcaaag gaggcttcag acatcatcct aacagatgac     3360

aacttcacca gcattgtgaa ggcagtgatg tggggacgaa atgtctatga cagcatctcc     3420

aagttcctgc agttccagct cactgtcaat gtggtggccg tgattgtagc cttcactgga     3480

gcctgtatca ctcaggattc cccattgaaa gctgtgcaga tgttgtgggt taatctgatc     3540

atggacactt ttgcttcatt ggccctggcc acagagcccc ctacggaatc tctgttgaag     3600

cggcgcccct atggccgaaa taagcctctg atctcacgca ctatgatgaa gaacatcttg     3660

ggccatgcat tctatcagct cattgtcatc tttatccttg tctttgcggg tgagaaattc     3720

tttgatattg atagtgggag gaaggcacct ctacattcac cacccagcca gcactatacc     3780

attgttttta acaccttcgt gctgatgcag ctcttcaatg aaatcaactc ccgaaagatc     3840

catggagaga agaacgtctt ttcaggcatc taccgcaaca ttatcttctg ctctgtagtc     3900

ttgggcacat tcatctgcca gattttcatc gtggaatttg ggggtaaacc cttcagttgt     3960

acaagcctca gcctgtctca gtggctgtgg tgtctcttca ttgggattgg agaacttctg     4020

tggggccagt tcatctccgc aatacctacc cgatccctga agttcctgaa ggaggctggg     4080

catggcacca ccaaagagga gatcaccaag gatgccgagg gactggatga gattgaccat     4140

gctgagatgg agctgcgccg aggccagatc ctctggttcc ggggcctgaa ccgtatccag     4200

actcagatca aagtggtcaa agcgttccat agttccctcc acgaaagcat tcagaaaccc     4260

tacaaccaaa agtccatcca cagcttcatg acccaccctg aattcgccat agaggaggag     4320

ttgccacgaa caccactcct ggatgaggaa gaggaggaaa atcctgacaa ggcttctaag     4380

tttgggacta gggtgctcct gttggatggt gaggtcactc catatgccaa tacaaacaac     4440

aatgcggtgg attgcaacca agtgcagctc ccccagtcgg acagctctct acagagccta     4500

gagacatcag tttgaatttt ctttctctga ctctcatccc tattttacct atttccattt     4560

tcgtctatcc catctatgag gtgatgatgg gacttttcat tgtcacgtca gctgctgtgt     4620

taacagcagt gtgtgtgaag tgaacctcta cctgaccatg aagaggcaag agcacagact     4680

tacaaggatt tcaacttaag cttgacttgg ggtttgtagc gggacccagt caaaccccat     4740

tcaggtcatg gtagaatcta ctccttggta gtcacttgtc atttttaaag aaatgatgac     4800

aatcctcttg gcatcacccc accccacatt ctccccgatg ttcctctcct gaattctgga     4860

ttttgtccta caagtctgtg ccatttataa gctaagttga gggttcagag ggagacaaat     4920

atccccaagt gaaatatgtt gcggtagaga tggaatgtat aaaatccgcc agtagtgtga     4980

ttgtttttca atttttccca ctttgaaaac ttacacctaa aggcctgtag gcctctaact     5040

ctttctgccc tttcattcaa acctctccaa agttctttgt cttttgtctt cccttccttt     5100

cctttttttt tttttttttt atgatgatta agaaaatgga aaggatatgg atgaattgtg     5160

taaacttaga tccttctccc ttttggccca aaagaaccct tgatttagtt ccagaatcca     5220

accagtttct ttgttaaaag ggtccttttg aagcaattaa gtgctggtaa gaatatttct     5280

ctgttgttgc caggttacct tctgctttta aattgccatc ttgtaaagtg tatgtggttc     5340

ttaagtgcca gggagatcag ccttgcccat gaaggttgca tatgtgtggt atacagtttt     5400

tacctgaaag cctgagcttt ctcttattcc taaagtggtg gcaaaagaat gaactgggta     5460

tgaccctgcc cccttactgg gcttggatat tgaggaccag acgctgccaa atctaggaca     5520

agacagacca tcaaagcaga cttttgtggg ctcctctttg gggtgaccac tgctttcaaa     5580

gccatctgcc aaggctctcc agggcaggac ctgactggtg gggaatgagt gttcagaagc     5640

cttgggagag gccaaagagc cattctagca tgatctgaga aaaccttcct gcagaggcca     5700

gaaaccttga gcttaggtgc ctggggacca gcttcgacat tctctccagt ttctgattct     5760

aatttttgcc acgtgtcaca acttttccag tctctgagaa ggtcccagcc tttctcaaat     5820

attctgattt tgaaaatatg tatccaaagt gggaggcccc tgtgacattt tgccaactta     5880

aacgagaaaa agaccccccg cacccggcac actccccctt cctccagccc cgcttcagcc     5940

acatgctcca gctgctgccc agtaaagccc tgtgcctttt tttcccctga atactgccca     6000

aagcatcccc ttcccatctg cctctcagga gttggggact ttgctaggag attttttaag     6060

tgttccttac tgggacaacg tggagccacg tttgcaggag ctccatttgt atccctgctg     6120

gtgttgactt ctgtgtaggg gccagttcat gtccctgact ctcacctccc attagataaa     6180

tgaagcccac ccccctttct agagtgatga gagtcaagaa gaggggatgt atgaacggcc     6240

aaattcccat gtgagaggaa gatgacctga tccacctagc cttttcttct ggatctgtcc     6300

tccctcaccc ctttcacctg agctgtccac agtaggaaac ataaagaaac aatgtcccct     6360

acatatcccc atgactacat aatccatcat cgtaggaaat aggaaagcaa atttgatttt     6420

ggttttgtaa aacgtacatg cttcaataat tcttttttgt gtcttaaata ctcatagggg     6480

aaaaaaacag ctcacccaag gtgttaggtt tcacatatat attcatcaac tattttagaa     6540

gatttaattc tatcaaatct tgtattacct cagatcattt taaatagcaa gccaataacg     6600

agctttgaag gctattttac cattcctgtt cacaaaaggt tctcatggtg cctgacaggt     6660

tacccttgag ggcttgtgtc tactttttaa aagtcaatgg ttttttttct tgtgttctag     6720

tttccataat aggagagaaa atatagaaat atatgcaaaa attatagttt tctttagatc     6780

agaaactgat atttttgggt cagccatatg tattttgttt aaaggattta aaataaagtg     6840

ccgtcatgta gccctgtgga agggagcaca taaccagctg tttggcatga caggtgactt     6900

agtatatttg taattggttt taaaaccaat acaccatact ttctttctgc aaacagccat     6960

ctttatactt agggaagaaa aattgttggg ttctagactt ttttaatata aattttgttg     7020

atatggaatt aggtaagttt aagtgtctat gtgcatatgt tttttatata agttttttct     7080

attcagtttc actgatccaa ctggcagtgg gtaaatatgg cataagttaa taacactttt     7140

ccccaaaatg gtgctttgga tttgaaaagg gtctgatggg gagaaggaga acgtatcatc     7200

ctagcttcct ctcttaataa acctagaaaa acgggtagta aactgtggat agtcaggaaa     7260

acacccagca agggacacag ctgtcaggaa atgaatcttc cccccaaccc ccaccatgca     7320

gatggataga cagaatcttt cctgactagt cattaggatc aggggcctct gttggatttg     7380

tgtttcttga agaatagctg gcagagtggt ataaaagaca cgaatatctc ctggtctata     7440

aggatactct gatttggggt ttgcattttt catggttttt atttcctgtt ccccctggag     7500

ttttccatta gtgagttttt gtgcaaggat cttatttgtg atgccttccc tcccctagaa     7560

agattttgtg caatatatta aatggggaca gaattctaaa tggataaaac aatggctggt     7620

tctagccctg agtgacagtc ttaaggctag atccttccca tagtatcatc tgtcctctgg     7680

aatgactctc ctgtccctaa aggggttaag agagagatca cctagaaatc cctctggaca     7740

cttgtgggtt ctttagggtt tgagtttctt cttccccttg agcttcagag aggagagttg     7800

gcatggttaa atctgaatgg ttacctcact gctgaaaacc cagaggggcg tggcacactc     7860

gcttgtgtgg aaaagcctct aaatgcatcc cttcctttct ttcctgcttc ctttgcctta     7920

caattgaagc agcccgtggt accatcacag tatgcagaga cttcctcacc tttcatatct     7980

agggaccacc cccgatgcat tggtgagggt gggcacttat aaatgcctgc tattgttaag     8040

ccattccagc ctcttcctct gaatagacca gacgcccttt cacttagttc agtgccagtc     8100

cttttgcctt cccaaccctg ctgttaggcc tgctgttccc tttgctcttg attaggagag     8160

atggaaggag atgagctccc ataactgaat tggcctttgg ttcatgtttt ctccccatat     8220

gtatatatgc catatgtgaa tatgccatat atatgtgcca acaaatctat ctacgttgtt     8280

cttttcaaat tagcacgcag ataggaattt tgagtttctt cttcttttag taactagtat     8340

aacaagcact ggtatttttg tacaaaaaag aaaaacaaaa gattgactat tgtggtctgc     8400

atgacataaa caaacaaatg gtgatatcaa agcaacgtat accccagtcc agtgtgtgtt     8460

gccataattt gcaattcagc ttaacagtgc acccaatcta tatttgcatt ttgatattat     8520

ttaagctcta tgtacaaggt tttgcatgta tttatatggt tcttagggaa aaaaaatgct     8580

ataaactgca aatctgaaat tcaaatgtgt tgttccactg agaccagaag aagaagagga     8640

gttttaaaag ggataatttg ttggagccaa taaagctttt tgctgatgaa cagaaaccaa     8700

tactgctgtg cactgagaat aaaaactcat gcccacttgt aaaaaaaaaa aaa            8753


<210>  1637
<211>  1314
<212>  DNA
<213>  homo sapiens

<400>  1637
cggggcggga gatttgaaaa gtccttggcc agggcgcggc gtggcagatt cagttgtttg       60

cgggcggccg ggagagtagc agtgccttgg accccagctc tcctccccct ttctctctaa      120

ggatggccca gaaggagaac tcctacccct ggccctacgg ccgacagacg gctccatctg      180

gcctgagcac cctgccccag cgagtcctcc ggaaagagcc tgtcacccca tctgcacttg      240

tcctcatgag ccgctccaat gtccagccca cagctgcccc tggccagaag gtgatggaga      300

atagcagtgg gacacccgac atcttaacgc ggcacttcac aattgatgac tttgagattg      360

ggcgtcctct gggcaaaggc aagtttggaa acgtgtactt ggctcgggag aagaaaagcc      420

atttcatcgt ggcgctcaag gtcctcttca agtcccagat agagaaggag ggcgtggagc      480

atcagctgcg cagagagatc gaaatccagg cccacctgca ccatcccaac atcctgcgtc      540

tctacaacta tttttatgac cggaggagga tctacttgat tctagagtat gccccccgcg      600

gggagctcta caaggagctg cagaagagct gcacatttga cgagcagcga acagccacga      660

tcatggagga gttggcagat gctctaatgt actgccatgg gaagaaggtg attcacagag      720

acataaagcc agaaaatctg ctcttagggc tcaagggaga gctgaagatt gctgacttcg      780

gctggtctgt gcatgcgccc tccctgagga ggaagacaat gtgtggcacc ctggactacc      840

tgcccccaga gatgattgag gggcgcatgc acaatgagaa ggtggatctg tggtgcattg      900

gagtgctttg ctatgagctg ctggtgggga acccaccctt tgagagtgca tcacacaacg      960

agacctatcg ccgcatcgtc aaggtggacc taaagttccc cgcttccgtg cccatgggag     1020

cccaggacct catctccaaa ctgctcaggc ataacccctc ggaacggctg cccctggccc     1080

aggtctcagc ccacccttgg gtccgggcca actctcggag ggtgctgcct ccctctgccc     1140

ttcaatctgt cgcctgatgg tccctgtcat tcactcgggt gcgtgtgttt gtatgtctgt     1200

gtatgtatag gggaaagaag ggatccctaa ctgttccctt atctgttttc tacctcctcc     1260

tttgtttaat aaaggctgaa gctttttgta ctcatgaaaa aaaaaaaaaa aaaa           1314


<210>  1638
<211>  8573
<212>  DNA
<213>  homo sapiens

<400>  1638
gagtagctcc agcggccacg ctgaggcgag ggtgacacac catgctcacg gcccctggag       60

accgtcgtgc tggcgagccg tgctccgtag ctccccggtc cgcctcggca gcggtcagag      120

tcgcctacag gagttgagcc gcccgcgcca gaaggttttg gcgaagctct tggagaggcg      180

tcgagcacag tagggcggcg ggggtgcgtt gagcgctcgg gggtcaggca gtcggccggg      240

atcgccgctg gggagcgttt ccgaggcgag gaggaggagg aggagatgct gctcctcttc      300

tccccctccc caggctcctt ctacagctcc ttcagcccac gcccgcagcc gcttgtggga      360

gaagtggtgg tggctctcgg cgcccgcggc ggctgccggc ggcccgcccc gacgccgcgt      420

ccctgcagcc ctcgcccggc gctccagtag caggacccgg tctcgggacc agccggtaat      480

atgcacgtgt cactagctga ggccctggag gttcggggtg gaccacttca ggaggaagaa      540

atatgggctg tattaaatca aagtgctgaa agtctccaag aattattcag aaaagtaagc      600

ctagctgatc ctgctgccct tggcttcatc atttctccat ggtctctgct gttgctgcca      660

tctggtagtg tgtcatttac agatgaaaat atttccaatc aggatcttcg agcattcact      720

gcaccagagg ttcttcaaaa tcagtcacta acttctctct cagatgttga aaagatccac      780

atttattctc ttggaatgac actgtattgg ggggctgatt atgaagtgcc tcagagccaa      840

cctattaagc ttggagatca tctcaacagc atactgcttg gaatgtgtga ggatgttatt      900

tacgctcgag tttctgttcg gactgtgctg gatgcttgca gtgcccacat taggaatagc      960

aattgtgcac cctcattttc ctacgtgaaa cacttggtaa aactggttct gggaaatctt     1020

tctgggacag atcagctttc ctgtaacagt gaacaaaagc ctgatcgaag ccaggctatt     1080

cgagatcgat tgcgaggaaa aggattacca acaggaagaa gctctacttc tgatgtacta     1140

gacatacaaa agcctccact ctctcatcag acctttctta acaaagggct tagtaaatct     1200

atgggatttc tgtccatcaa agatacacaa gatgagaatt atttcaagga cattttatca     1260

gataattctg gacgtgaaga ttctgaaaat acattctccc cttaccagtt caaaactagt     1320

ggcccagaaa aaaaacccat ccctggcatt gatgtgcttt ctaagaagaa gatctgggct     1380

tcatccatgg acttgctttg tacagctgac agagacttct cttcaggaga gactgccaca     1440

tatcgtcgtt gtcaccctga ggcagtaaca gtgcggactt caactactcc tagaaaaaag     1500

gaggcaagat actcagatgg aagtatagcc ttggatatct ttggccctca gaaaatggat     1560

ccaatatatc acactcgaga attgcccacc tcctcagcaa tatcaagtgc tttggaccga     1620

atccgagaga gacaaaagaa acttcaggtt ctgagggaag ccatgaatgt agaagaacca     1680

gttcgaagat acaaaactta tcatggtgat gtctttagta cctccagtga aagtccatct     1740

attatttcct ctgaatcaga tttcagacaa gtgagaagaa gtgaagcctc aaagaggttt     1800

gaatccagca gtggtctccc aggggtagat gaaaccttaa gtcaaggcca gtcacagaga     1860

ccgagcagac aatatgaaac accctttgaa ggcaacttaa ttaatcaaga gatcatgcta     1920

aaacggcaag aggaagaact gatgcagcta caagccaaaa tggcccttag acagtctcgg     1980

ttgagcctat atccaggaga cacaatcaaa gcgtccatgc ttgacatcac cagggatccg     2040

ttaagagaaa ttgccctaga aacagccatg actcaaagaa aactgaggaa tttctttggc     2100

cctgagtttg tgaaaatgac aattgaacca tttatatctt tggatttgcc acggtctatt     2160

cttactaaga aagggaagaa tgaggataac cgaaggaaag taaacataat gcttctgaac     2220

gggcaaagac tggaactgac ctgtgatacc aaaactatat gtaaagatgt gtttgatatg     2280

gttgtggcac atattggctt agtagagcat catttgtttg ctttagctac cctcaaagat     2340

aatgaatatt tctttgttga tcctgactta aaattaacca aagtggcccc agagggatgg     2400

aaagaagaac caaagaaaaa gaccaaagcc actgttaatt ttactttgtt tttcagaatt     2460

aaatttttta tggatgatgt tagtctaata caacatactc tgacgtgtca tcagtattac     2520

cttcagcttc gaaaagatat tttggaggaa aggatgcact gtgatgatga gacttcctta     2580

ttgctggcat ccttggctct ccaggctgag tatggagatt atcaaccaga ggttcatggt     2640

gtgtcttact ttagaatgga gcactatttg cccgccagag tgatggagaa acttgattta     2700

tcctatatca aagaagagtt acccaaattg cataatacct atgtgggagc ttctgaaaaa     2760

gagacagagt tagaattttt aaaggtctgc caaagactga cagaatatgg agttcatttt     2820

caccgagtgc accctgagaa gaagtcacaa acaggaatat tgcttggagt ctgttctaaa     2880

ggtgtccttg tgtttgaagt tcacaatgga gtgcgcacat tggtccttcg ctttccatgg     2940

agggaaacca agaaaatatc tttttctaaa aagaaaatca cattgcaaaa tacatcagat     3000

ggaataaaac atggcttcca gacagacaac agtaagatat gccagtacct gctgcacctc     3060

tgctcttacc agcataagtt ccagctacag atgagagcaa gacagagcaa ccaagatgcc     3120

caagatattg agagagcttc gtttaggagc ctgaatctcc aagcagagtc tgttagagga     3180

tttaatatgg gacgagcaat cagcactggc agtctggcca gcagcaccct caacaaactt     3240

gctgttcgac ctttatcagt tcaagctgag attctgaaga ggctatcctg ctcagagctg     3300

tcgctttacc agccattgca aaacagttca aaagagaaga atgacaaagc ttcatgggag     3360

gaaaagccta gagagatgag taaatcatac catgatctca gtcaggcctc tctctatcca     3420

catcggaaaa atgtcattgt taacatggaa cccccaccac aaaccgttgc agagttggtg     3480

ggaaaacctt ctcaccagat gtcaagatct gatgcagaat ctttggcagg agtgacaaaa     3540

cttaataatt caaagtctgt tgcgagttta aatagaagtc ctgaaaggag gaaacatgaa     3600

tcagactcct catccattga agaccctggg caagcatatg ttctaggaat gactatgcat     3660

agttctggaa actcttcatc ccaagtaccc ttaaaagaaa atgatgtgct acacaaaaga     3720

tggagcatag tatcttcacc agaaagggag atcaccttag tgaacctgaa aaaagatgca     3780

aagtatggct tgggatttca aattattggt ggggagaaga tgggaagact ggacctaggc     3840

atatttatca gttcagttgc ccctggagga ccagctgact tggatggatg cttgaagcca     3900

ggagaccgtt tgatatctgt gaatagtgtg agtctggagg gagtcagcca ccatgctgca     3960

attgaaattt tgcaaaatgc acctgaagat gtgacacttg ttatctctca gccaaaagaa     4020

aagatatcca aagtgccttc tactcctgtg catctcacca atgagatgaa aaactacatg     4080

aagaaatctt cctacatgca agacagtgct atagattctt cttccaagga tcaccactgg     4140

tcacgtggta ccctgaggca catctcggag aactcctttg ggccatctgg gggcctgcgg     4200

gaaggaagcc tgagttctca agattccagg actgagagtg ccagcttgtc tcaaagccag     4260

gtcaatggtt tctttgccag ccatttaggt gaccaaacct ggcaggaatc acagcatggc     4320

agcccttccc catctgtaat atccaaagcc accgagaaag agactttcac tgatagtaac     4380

caaagcaaaa ctaaaaagcc aggcatttct gatgtaactg attactcaga ccgtggagat     4440

tcagacatgg atgaagccac ttactccagc agtcaggatc atcaaacacc aaaacaggaa     4500

tcttcctctt cagtgaatac atccaacaag atgaatttta aaactttttc ttcatcacct     4560

cctaagcctg gagatatctt tgaggttgaa ctggctaaaa atgataacag cttggggata     4620

agtgtcacgg gaggtgtgaa tacgagtgtc agacatggtg gcatttatgt gaaagctgtt     4680

attccccagg gagcagcaga gtctgatggt agaattcaca aaggtgatcg cgtcctagct     4740

gtcaatggag ttagtctaga aggagccacc cataagcaag ctgtggaaac actgagaaat     4800

acaggacagg tggttcatct gttattagaa aagggacaat ctccaacatc taaagaacat     4860

gtcccggtaa ccccacagtg taccctttca gatcagaatg cccaaggtca aggcccagaa     4920

aaagtgaaga aaacaactca ggtcaaagac tacagctttg tcactgaaga aaatacattt     4980

gaggtaaaat tatttaaaaa tagctcaggt ctaggattca gtttttctcg agaagataat     5040

cttataccgg agcaaattaa tgccagcata gtaagggtta aaaagctctt tcctggacag     5100

ccagcagcag aaagtggaaa aattgatgta ggagatgtta tcttgaaagt gaatggagcc     5160

tctttgaaag gactatctca gcaggaagtc atatctgctc tcaggggaac tgctccagaa     5220

gtattcttgc ttctctgcag acctccacct ggtgtgctac cggaaattga tactgcgctt     5280

ttgaccccac ttcagtctcc agcacaagta cttccaaaca gcagtaaaga ctcttctcag     5340

ccatcatgtg tggagcaaag caccagctca gatgaaaatg aaatgtcaga caaaagcaaa     5400

aaacagtgca agtccccatc cagaagagac agttacagtg acagcagtgg gagtggagaa     5460

gatgacttag tgacagctcc agcaaacata tcaaattcga cctggagttc agctttgcat     5520

cagactctaa gcaacatggt atcacaggca cagagtcatc atgaagcacc caagagtcaa     5580

gaagatacca tttgtaccat gttttactat cctcagaaaa ttcccaataa accagagttt     5640

gaggacagta atccttcccc tctaccaccg gatatggctc ctgggcagag ttatcaaccc     5700

caatcagaat ctgcttcctc tagttcgatg gataagtatc atatacatca catttctgaa     5760

ccaactagac aagaaaactg gacacctttg aaaaatgact tggaaaatca ccttgaagac     5820

tttgaactgg aagtagaact cctcattacc ctaattaaat cagaaaaagg aagcctgggt     5880

tttacagtaa ccaaaggcaa tcagagaatt ggttgttatg ttcatgatgt catacaggat     5940

ccagccaaaa gtgatggaag gctaaaacct ggggaccggc tcataaaggt taatgataca     6000

gatgttacta atatgactca tacagatgca gttaatctgc tccgggctgc atccaaaaca     6060

gtcagattag ttattggacg agttctagaa ttacccagaa taccaatgtt gcctcatttg     6120

ctaccggaca taacactaac gtgcaacaaa gaggagttgg gtttttcctt atgtggaggt     6180

catgacagcc tttatcaagt ggtatatatt agtgatatta atccaaggtc cgtcgcagcc     6240

attgagggta atctccagct attagatgtc atccattatg tgaacggagt cagcacacaa     6300

ggaatgacct tggaggaagt taacagagca ttagacatgt cacttccttc attggtattg     6360

aaagcaacaa gaaatgatct tccagtggtc cccagctcaa agaggtctgc tgtttcagct     6420

ccaaagtcaa ccaaaggcaa tggttcctac agtgtggggt cttgcagcca gcctgccctc     6480

actcctaatg attcattctc cacggttgct ggggaagaaa taaatgaaat atcgtacccc     6540

aaaggaaaat gttctactta tcagataaag ggatcaccaa acttgactct gcccaaagaa     6600

tcttatatac aagaagatga catttatgat gattcccaag aagctgaagt tatccagtct     6660

ctgctggatg ttgtggatga ggaagcccag aatcttttaa acgaaaataa tgcagcagga     6720

tactcctgtg gtccaggtac attaaagatg aatgggaagt tatcagaaga gagaacagaa     6780

gatacagact gcgatggttc acctttacct gagtatttta ctgaggccac caaaatgaat     6840

ggctgtgaag aatattgtga agaaaaagta aaaagtgaaa gcttaattca gaagccacaa     6900

gaaaagaaga ctgatgatga tgaaataaca tggggaaatg atgagttgcc aatagagaga     6960

acaaaccatg aagattctga taaagatcat tcctttctga caaacgatga gctcgctgta     7020

ctccctgtcg tcaaagtgct tccctctggt aaatacacgg gtgccaactt aaaatcagtc     7080

attcgagtcc tgcggggttt gctagatcaa ggaattcctt ctaaggagct ggagaatctt     7140

caagaattaa aacctttgga tcagtgtcta attgggcaaa ctaaggaaaa cagaaggaag     7200

aacagatata aaaatatact tccctatgat gctacaagag tgcctcttgg agatgaaggt     7260

ggctatatca atgccagctt cattaagata ccagttggga aagaagagtt cgtttacatt     7320

gcctgccaag gaccactgcc tacaactgtt ggagacttct ggcagatgat ttgggagcaa     7380

aaatccacag tgatagccat gatgactcaa gaagtagaag gagaaaaaat caaatgccag     7440

cgctattggc ccaacatcct aggcaaaaca acaatggtca gcaacagact tcgactggct     7500

cttgtgagaa tgcagcagct gaagggcttt gtggtgaggg caatgaccct tgaagatatt     7560

cagaccagag aggtgcgcca tatttctcat ctgaatttca ctgcctggcc agaccatgat     7620

acaccttctc aaccagatga tctgcttact tttatctcct acatgagaca catccacaga     7680

tcaggcccaa tcattacgca ctgcagtgct ggcattggac gttcagggac cctgatttgc     7740

atagatgtgg ttctgggatt aatcagtcag gatcttgatt ttgacatctc tgatttggtg     7800

cgctgcatga gactacaaag acacggaatg gttcagacag aggatcaata tattttctgc     7860

tatcaagtca tcctttatgt cctgacacgt cttcaagcag aagaagagca aaaacagcag     7920

cctcagcttc tgaagtgaca tgaaaagagc ctctggatgc atttccattt ctctccttaa     7980

cctccagcag actcctgctc tctatccaaa ataaagatca cagagcagca agttcataca     8040

acatgcatgt tctcctctat cttagagggg tattcttctt gaaaataaaa aatattgaaa     8100

tgctgtattt ttacagctac tttaacctat gataattatt tacaaaattt taacactaac     8160

caaacaatgc agatcttagg gatgattaaa ggcagcattt gatgatagca gacattgtta     8220

caaggacatg gtgagtctat ttttaatgca ccaatcttgt ttatagcaaa aatgttttcc     8280

aatattttaa taaagtagtt attttatagg ggatacttga aaccagtatt taagctttaa     8340

atgacagtaa tattggcata gaaaaaagta gcaaatgttt actgtatcaa tttctaatgt     8400

ttactatata gaatttcctg taatatattt atatactttt tcatgaaaat ggagttatca     8460

gttatctgtt tgttactgca tcatctgttt gtaatcatta tctcactttg taaataaaaa     8520

cacaccttaa aacatgaaca agccaaaact gtgtgcagac aaaaaaaaaa aaa            8573


<210>  1639
<211>  2010
<212>  DNA
<213>  homo sapiens

<400>  1639
gggtctgcgg gaagcccgag ccggggcggg cccgagtcaa aggcaagtga aggtggaagc       60

ggccgcggcg gcagcaggcc accatggcgg agctgcagga ggtgcagatc acagaggaga      120

agccactgtt gccaggacag acgcctgagg cggccaagac tcactctgtg gagacaccat      180

acggctctgt cactttcact gtctatggca cccccaaacc caaacgccca gcgatcctta      240

cctaccacga tgtgggactc aactataaat cttgcttcca gccactgttt cagttcgagg      300

acatgcagga aatcattcag aactttgtgc gggttcatgt ggatgcccct ggaatggaag      360

agggagcccc tgtgttccct ttgggatatc agtacccatc tctggaccag cttgcagaca      420

tgatcccttg cgtcctgcag tacctaaatt tctctacaat aattggagtt ggtgttggag      480

ctggagccta catcctggcg agatatgctc ttaaccaccc ggacactgtt gaaggtcttg      540

tcctcatcaa cattgatccc aatgccaagg gttggatgga ttgggcagcc cacaagctaa      600

caggcctcac ctcttccatt ccggagatga tccttggaca tcttttcagc caggaagagc      660

tctctggaaa ttctgagttg atacaaaagt acagaaatat cattacacat gcacccaacc      720

tggataacat tgaattgtac tggaacagct acaacaaccg ccgagacctg aactttgagc      780

gtggaggtga tatcaccctc aggtgtcctg tgatgctggt ggtaggagac caagcacctc      840

atgaagatgc agtggtggaa tgtaactcaa aactggaccc cacccagacc tcgttcctca      900

agatggctga ctccggaggt cagccccagc tgactcagcc aggcaagctg accgaggcct      960

tcaagtactt cctgcaaggc atgggctaca tggcctcatc ctgcatgact cgcctgtccc     1020

ggtctcgtac agcctctctg accagtgcag catccgttga tggcaaccgg tcccgctctc     1080

gcaccctgtc ccagagcagc gagtctggaa ctctttcttc ggggcccccg gggcacacca     1140

tggaggtctc ctgttgaatg gcccttgttg ccctagagtg ggacccagcc ctcacctccc     1200

ccagagctaa cctgggaggt gctgaagggg cattgggcca ccgtaagcaa gggaaaaagg     1260

gcagatcatg cggggagatg accttgatct ttgattgcta ccctaacctt gacctttaac     1320

ccgtgattcc ccccagctcc tggaagagat gtcctaatat ctcttaggga cccagacccc     1380

taaattctcc tcctccccca ttttgatgtt aaggtggaga gggcatatgc atcctctgtc     1440

ctgatctagg tgtctatagc tgaggggtaa gaggttgttg tagttgtcct ggtgcctcca     1500

tcagactctc cctacttgtc ccatatttgc aaggggaggg gatttggggc tggggctcca     1560

ttcaccaaag ctgaggtggc ttctcattaa ccctttagga ctctgaaggg tatggaccta     1620

cgtgaatgtg tgtcaggggg agacttgctg gtgggttagt ggtcctcagg atgtgataga     1680

aacatccagt gtaaaaagga agttggaatg ggagttggcg ggcagtgaac gagtgtgggg     1740

aaggattggt gctggggcaa caggaagggg cctggggccg tttggctgca ctaactttgg     1800

tagctcagtg tgcatctaga gtgggactgg ggagggagct aagcttgggc tgggctgctt     1860

ggggcttggc atagggtgga aagggctacc ctggggctct gaccacactg tagtatgtgt     1920

ggagggtgcc ctcccgtctc ccacaacttc tgctataaca ataaactgta gaggaatctg     1980

agtaccgtta aaaaaaaaaa aaaaaaaaaa                                      2010


<210>  1640
<211>  2052
<212>  DNA
<213>  homo sapiens

<400>  1640
gggtctgcgg gaagcccgag ccggggcggg cccgagtcaa aggcaagtga aggtggaagc       60

ggccgcggcg gcagcaggcc accatggcgg agctgcagga ggtgcagatc acagaggaga      120

agccactgtt gccaggacag acgcctgagg cggccaagga ggctgagtta gctgcccgaa      180

tcctcctgga ccagggacag actcactctg tggagacacc atacggctct gtcactttca      240

ctgtctatgg cacccccaaa cccaaacgcc cagcgatcct tacctaccac gatgtgggac      300

tcaactataa atcttgcttc cagccactgt ttcagttcga ggacatgcag gaaatcattc      360

agaactttgt gcgggttcat gtggatgccc ctggaatgga agagggagcc cctgtgttcc      420

ctttgggata tcagtaccca tctctggacc agcttgcaga catgatccct tgcgtcctgc      480

agtacctaaa tttctctaca ataattggag ttggtgttgg agctggagcc tacatcctgg      540

cgagatatgc tcttaaccac ccggacactg ttgaaggtct tgtcctcatc aacattgatc      600

ccaatgccaa gggttggatg gattgggcag cccacaagct aacaggcctc acctcttcca      660

ttccggagat gatccttgga catcttttca gccaggaaga gctctctgga aattctgagt      720

tgatacaaaa gtacagaaat atcattacac atgcacccaa cctggataac attgaattgt      780

actggaacag ctacaacaac cgccgagacc tgaactttga gcgtggaggt gatatcaccc      840

tcaggtgtcc tgtgatgctg gtggtaggag accaagcacc tcatgaagat gcagtggtgg      900

aatgtaactc aaaactggac cccacccaga cctcgttcct caagatggct gactccggag      960

gtcagcccca gctgactcag ccaggcaagc tgaccgaggc cttcaagtac ttcctgcaag     1020

gcatgggcta catggcctca tcctgcatga ctcgcctgtc ccggtctcgt acagcctctc     1080

tgaccagtgc agcatccgtt gatggcaacc ggtcccgctc tcgcaccctg tcccagagca     1140

gcgagtctgg aactctttct tcggggcccc cggggcacac catggaggtc tcctgttgaa     1200

tggcccttgt tgccctagag tgggacccag ccctcacctc ccccagagct aacctgggag     1260

gtgctgaagg ggcattgggc caccgtaagc aagggaaaaa gggcagatca tgcggggaga     1320

tgaccttgat ctttgattgc taccctaacc ttgaccttta acccgtgatt ccccccagct     1380

cctggaagag atgtcctaat atctcttagg gacccagacc cctaaattct cctcctcccc     1440

cattttgatg ttaaggtgga gagggcatat gcatcctctg tcctgatcta ggtgtctata     1500

gctgaggggt aagaggttgt tgtagttgtc ctggtgcctc catcagactc tccctacttg     1560

tcccatattt gcaaggggag gggatttggg gctggggctc cattcaccaa agctgaggtg     1620

gcttctcatt aaccctttag gactctgaag ggtatggacc tacgtgaatg tgtgtcaggg     1680

ggagacttgc tggtgggtta gtggtcctca ggatgtgata gaaacatcca gtgtaaaaag     1740

gaagttggaa tgggagttgg cgggcagtga acgagtgtgg ggaaggattg gtgctggggc     1800

aacaggaagg ggcctggggc cgtttggctg cactaacttt ggtagctcag tgtgcatcta     1860

gagtgggact ggggagggag ctaagcttgg gctgggctgc ttggggcttg gcatagggtg     1920

gaaagggcta ccctggggct ctgaccacac tgtagtatgt gtggagggtg ccctcccgtc     1980

tcccacaact tctgctataa caataaactg tagaggaatc tgagtaccgt taaaaaaaaa     2040

aaaaaaaaaa aa                                                         2052


<210>  1641
<211>  1652
<212>  DNA
<213>  homo sapiens

<400>  1641
acggggcggg gtctggggcc cgccctcccg acacgtggcc ggggaccggg tatataaggc       60

ccttcggggc cggccaccct ttcactactt ctcccccgga ctccttggta gtctgttagt      120

gggagatcct tgttgccgtc ccttcgcctc cttcaccgcc gcagacccct tcaagttcta      180

gtcatgcgtg agtgcatctc catccacgtt ggccaggctg gtgtccagat tggcaatgcc      240

tgctgggagc tctactgcct ggaacacggc atccagcccg atggccagat gccaagtgac      300

aagaccattg ggggaggaga tgattccttc aacaccttct tcagtgaaac gggtgctggc      360

aagcatgtgc cccgggcagt gtttgtagac ttggaaccca cagtcattga tgaagttcgc      420

actggcactt accgccagct cttccaccct gagcaactca tcacaggcaa ggaagatgct      480

gccaataact atgcccgagg gcactacacc attggcaagg agatcattga cctcgtgttg      540

gaccgaattc gcaagctggc tgaccagtgc accggtcttc agggcttctt ggttttccac      600

agctttggtg ggggaactgg ttctgggttc acctcgctgc tcatggaacg tctctcagtt      660

gattatggca agaagtccaa gctggagttc tccatttacc cggcgcccca ggtttccaca      720

gctgtagttg agccctacaa ctccatcctc accacccaca ccaccctgga gcactctgat      780

tgtgccttca tggtagacaa tgaggccatc tatgacatct gtcgtagaaa cctcgatatc      840

gagcgcccaa cctacactaa ccttaaccgc cttattagcc agattgtgtc ctccatcact      900

gcttccctga gatttgatgg agccctgaat gttgacctga cagaattcca gaccaacctg      960

gtgccctacc cccgcatcca cttccctctg gccacatatg cccctgtcat ctctgctgag     1020

aaagcctacc acgaacagct tactgtagca gagatcacca atgcttgctt tgagccagcc     1080

aaccagatgg tgaaatgtga ccctcgccat ggtaaataca tggcttgctg cctgttatac     1140

cgtggtgacg tggttcccaa agatgtcaat gctgccattg ccaccatcaa aaccaagcgt     1200

accatccagt ttgtggattg gtgccccact ggcttcaagg ttggcattaa ttaccagcct     1260

cccactgtgg tgcctggcgg agacctggcc aaggtacaga gagctgtgtg catgctgagc     1320

aataccacag ctgttgccga ggcctgggct cgcctggacc acaagtttga cctgatgtat     1380

gccaagcgtg cctttgttca ctggtacgtg ggtgagggga tggaggaagg cgagttttca     1440

gaggcccgtg aggacatggc tgcccttgag aaggattatg aggaggttgg agcagatagt     1500

gctgacggag aggatgaggg tgaagagtat taacctgtgt gctgtacttt tacactcctt     1560

tgtcttggaa ctgtcttatt tttgttctgt aaatgtctat tgccgtaaat tgttaataaa     1620

attgaagttt ccattttaaa tgtcaaaaaa aa                                   1652


<210>  1642
<211>  3062
<212>  DNA
<213>  homo sapiens

<400>  1642
gggcggggcg gccgcgggtc gcgggcggat gacgcgccgg ggccggcgga ggagcagcca       60

cttcctgggg ccgccggccg gggccgctgg ctgcactcag cgccggagcc gggagctagc      120

ggccgccgcc atgtcccacc agaccggcat ccaagcaagt gaagatgtta aagagatctt      180

tgccagagcc agaaatggaa agtacagact tctgaaaata tctattgaaa atgagcaact      240

tgtgattgga tcatatagtc agccttcaga ttcctgggat aaggattatg attcctttgt      300

tttacccctg ttggaggaca aacaaccatg ctatatatta ttcaggttag attctcagaa      360

tgcccaggga tatgaatgga tattcattgc atggtctcca gatcattctc atgttcgtca      420

aaaaatgttg tatgcagcaa caagagcaac tctgaagaag gaatttggag gtggccacat      480

taaagatgaa gtatttggaa cagtaaagga agatgtatca ttacatggat ataaaaaata      540

cttgctgtca caatcttccc ctgccccact gactgcagct gaggaagaac tacgacagat      600

taaaatcaat gaggtacaga ctgacgtggg tgtggacact aagcatcaaa cactacaagg      660

agtagcattt cccatttctc gagaagcctt tcaggctttg gaaaaattga ataatagaca      720

gctcaactat gtgcagttgg aaatagatat aaaaaatgaa attataattt tggccaacac      780

aacaaataca gaactgaaag atttgccaaa gaggattccc aaggattcag ctcgttacca      840

tttctttctg tataaacatt cccatgaagg agactattta gagtccatag tttttattta      900

ttcaatgcct ggatacacat gcagtataag agagcggatg ctgtattcta gctgcaagag      960

ccgtctgcta gaaattgtag aaagacaact acaaatggat gtaattagaa agatcgagat     1020

agacaatggg gatgagttga ctgcagactt cctttatgaa gaagtacatc ccaagcagca     1080

tgcacacaag caaagttttg caaaaccaaa aggtcctgca ggaaaaagag gaattcgaag     1140

actaattagg ggcccagcgg aaactgaagc tactactgat taaagtcatc acattaaaca     1200

ttgtaatact agttttttaa aagtccagct tttagtacag gagaactgaa atcattccat     1260

gttgatataa agtagggaaa aaaattgtac tttttggaaa atagcacttt tcacttctgt     1320

gtgtttttaa aattaatgtt atagaagact catgatttct atttttgagt taaagctaga     1380

aaagggttca acataatgtt taattttgtc acactgtttt catagcgttg attccacact     1440

tcaaatactt cttaaaattt tatacagttg ggccagttct agaaagtctg atgtctcaaa     1500

gggtaaactt actactttct tgtgggacag aaagacctta aaatattcat attacttaat     1560

gaatatgtta aggaccaggc tagagtattt tctaagctgg aaacttagtg tgccttggaa     1620

aaggccgcaa gttgcttact ccgagtagct gtgctagctc tgtcagactg taggatcatg     1680

tctgcaactt ttagaaatag tgctttatat tgcagcagtc ttttatattt gacttttttt     1740

taatagcatt aaaattgcag atcagctcac tctgaaactt taagggtacc agatattttc     1800

tatactgcag gatttctgat gacattgaaa gactttaaac agccttagta aattatcttt     1860

ctaatgctct gtgaggccaa acatttatgt tcagattgaa atttaaatta atatcattca     1920

aaaggaaaca aaaaatgttg agttttaaaa atcaggattg acttttttct ccaaaaccat     1980

acatttatgg gcaaattgtg ttctttatca cttccgagca aatactcaga tttaaaatta     2040

ctttaaagtc ctggtactta acaggctaac gtagataaac accttaataa tctcagttaa     2100

tactgtattt caaaacacat ttaactgttt tctaatgctt tgcattatca gttacaacct     2160

agagagattt tgagcctcat atttctttga tacttgaaat agagggagct agaacactta     2220

atgtttaatc tgttaaacct gctgcaagag ccataacttt gaggcatttt ctaaatgaac     2280

tgtggggatc caggatttgt aatttcttga tctaaacttt atgctgcata aatcacttat     2340

cggaaatgca catttcatag tgtgaagcac tcatttctaa accttattat ctaaggtaat     2400

atatgcacct ttcagaaatt tgtgttcgag taagtaaagc atattagaat aattgtgggt     2460

tgacagattt ttaaaataga atttagagta tttggggttt tgtttgttta caaataatca     2520

gactataata tttaaacatg caaaataact gacaataatg ttgcacttgt ttactaaaga     2580

tataagttgt tccatgggtg tacacgtaga cagacacaca tacacccaaa ttattgcatt     2640

aagaatcctg gagcagacca tagctgaagc tgttattttc agtcaggaag actacctgtc     2700

atgaaggtat aaaataattt agaagtgaat gtttttctgt accatctatg tgcaattata     2760

ctctaaattc cactacacta cattaaagta aatggacatt ccagaatata gatgtgatta     2820

tagtcttaaa ctaattatta ttaaaccaat gattgctgaa aatcagtgat gcatttgtta     2880

tagagtataa ctcatcgttt acagtatgtt ttagttggca gtatcatacc tagatggtga     2940

ataacatatt cccagtaaat ttatatagca gtgaagaatt acatgccttc tggtggacat     3000

tttataagtg cattttatat cacaataaaa attttttctc tttaaaaaaa aaaaaaaaaa     3060

aa                                                                    3062


<210>  1643
<211>  1587
<212>  DNA
<213>  homo sapiens

<400>  1643
gcggcggttt tttttcccat ggcgctctgg ggcgcgggcg atttgtaggt aatggcaggc       60

gttcggtcac tgaggtgtag cagaggatgc gctggcggct gtgagtgcgg cgacaagggc      120

aaatgcagcg actcctcgct gttgggcaag agactctccg aagactcgag ccgccaccag      180

ctgttgcaga agtgggcgag catgtggagc tccatgagcg aagacgcgtc ggtggccgac      240

atggagaggg cgcagctgga ggaggaggcg gcggctgcgg aggagaggcc gctggtgttc      300

ctgtgctccg gctgccggcg gccgctgggc gactcgctga gctgggtggc cagccaggag      360

gacaccaact gcatcctgct tcgctgtgtt tcctgtaatg tttctgtgga taaggaacag      420

aagctatcca aacgtgaaaa ggaaaatggt tgcgtccttg agactttgtg ctgcgcgggg      480

tgctcactca atcttggcta cgtgtacaga tgcacgccca agaatcttga ttacaagaga      540

gacttgtttt gcctcagtgt tgaagccatt gaaagttatg ttttagggtc ctctgaaaag      600

caaattgtgt cagaagataa agagcttttt aatcttgaaa gcagagttga aatagaaaag      660

tctctaacac agatggaaga tgtcttgaaa gcattacaaa tgaagctgtg ggaggccgaa      720

tccaaattgt cctttgccac ttgtaaaagc tgaactctag tctgtgtcct ccattctgcc      780

cccgcccttc ctccccttat ttgttaaatg aagcaacata gtgagacgtc gtctctacaa      840

aaaaaaaaag aaaaaaaaaa ttagccaggc atgcgaaacg ctgaggtggg aggatcagat      900

gagcttggga ggttgaggct gcagtgagcc ttggtcatgc cactactgtg ttctagtctg      960

ggcaacagag tgagaccttc tctcaaaaaa aaaacccaaa attgtagaat tacttctata     1020

gctatatttt atgataaaga agtgattgtt tctcaaaatc gcattttaaa gacgttttat     1080

ggtacttgtt ggaattggga cttaggagtt ttgattttga taagaaactg ggataatttt     1140

ctgaactttt tttcctctgt atcacattta tttactattt ttaaaaactt tgacatttaa     1200

cacttgggac aacatttatt ataaatgata agaaaaatct tagaggtttg tctacccaca     1260

gtgtcatgga atcttctctg aaaactaatc cataaagttc cctggagaaa ttggtcagaa     1320

tgatctgtca gaaccatttg aaaacttgct caagagcagt tgcttatata tagtaggatt     1380

ttactttttc ctgcttatgt actactatat gcttaaaaaa cctggaggaa tacttaccaa     1440

agaggagtaa ccatctctga gggtgggatt ctgggggaat ttttgttttt ttctgttttc     1500

tataatgtga aacttttgta gtatgtattt ttctaattga agagaataaa gattaaaaca     1560

aagtgcttta aaaaaaaaaa aaaaaaa                                         1587


<210>  1644
<211>  3077
<212>  DNA
<213>  homo sapiens

<400>  1644
gcgcactcag caggttgggc tgcggcggcg gcggctgggg aagccgaagc gccgcgcgtg       60

agagatcccg gatacatctg cggtttgggc tccgccaccc tccgtctctc tcccgcaggt      120

ctctgagccg ggtgcggaag gagggaacgg ccctagcctt gggaagccaa agcacacccc      180

tggctcctgc cgacaccgcc ctccttccct tcccagccgc gggcctcgct ccgtgctcgg      240

ctactctgcc gggaggcggc ggcggctgcc agtctgtggc gagccctgct gccctccagc      300

cgggctcctc cagccgggct cctccaccgg cccttgcagg ggcgcagaga gctcggcgcc      360

cgcccttccg ctcgcctttt tcgtcagccg gctggaggag catcggtccg ggaggtctct      420

gggctgaggc ggcgacagct cctctagttc caccatgtcc gcgggcggag acttcgggaa      480

tccgctgagg aaattcaagc tggtgttcct gggggagcaa agcgttgcaa agacatcttt      540

gatcaccaga ttcaggtatg acagttttga caacacctat caggcaataa ttggcattga      600

ctttttatca aaaactatgt acttggagga tggaacaatc gggcttcggc tgtgggatac      660

ggcgggtcag gaacgtctcc gtagcctcat tcccaggtac atccgtgatt ctgctgcagc      720

tgtagtagtt tacgatatca caaatgttaa ctcattccag caaactacaa agtggattga      780

tgatgtcaga acagaaagag gaagtgatgt tatcatcacg ctagtaggaa atagaacaga      840

tcttgctgac aagaggcaag tgtcagttga ggagggagag aggaaagcca aagggctgaa      900

tgttacgttt attgaaacta gggcaaaagc tggatacaat gtaaagcagc tctttcgacg      960

tgtagcagca gctttgccgg gaatggaaag cacacaggac ggaagcagag aagacatgag     1020

tgacataaaa ctggaaaagc ctcaggagca aacagtcagc gaagggggtt gttcctgcta     1080

ctctcccatg tcatcttcaa cccttcctca gaagccccct tactctttca ttgactgcag     1140

tgtgaatatt ggcttgaacc ttttcccttc attaataacg ttttgcaatt catcattgct     1200

gcctgtctcg tggaggtgat ctattagctt cacaagcaca aaaaaagtca gcgtcttcat     1260

tatttatatt ttacaaaaag ccaaattatt tcagcatatt ccggtgataa ctttaaaaat     1320

tagatacatt ttcttaacat ttttttcttt tttaatgtta tgataatgta cttcaaaatg     1380

atggaaatct caacagtatg agtatggctt ggttaacgag cagtatgttc acagcctgct     1440

ttatctctcc ttgctcttct cacctctccc ttaccccgtt ccctatttcc gtgttcttac     1500

ctagcctccc cccacttcct caaaacaaac aagagatggc aaagcagcag tccgaccaag     1560

cccactggaa ttatccttta attttacaga taccacttgc tgtaggctgt ggaccaagat     1620

gtccagaatt attcttgagc actgatgtaa attacttaga tcttctttga ggtcagaatt     1680

cagcgatcac ggtaggcagt gcttgaatga gaaaagcctc ctggtgcatc ttcaaaatga     1740

gtcctaaaga acatactgag tacttataag tagcagaaca taaaatgtat ttctgactaa     1800

cacaaatggt cctttcacat gtgctttatt agactctggg agagaaaagt aaccaagtgc     1860

ttcagaacag gtttttagta tttacttctt catggtaaga taatgaagtt ctaatgaact     1920

atttctccca aggttttaaa attgtcaaga gttattctgt ttgtttaaaa agtaagaaac     1980

ctctgtaagc aatagatttt gcttgggttt tctttcttaa aaaaataata ctatgcaggc     2040

aagacaccat aaaagtttaa ttccttacag aagaaccagt ggaagaattt aaatttggca     2100

ctacgatcaa aactactgaa ttagcagaaa taacgatatc taaagcttac cagcaaaaga     2160

accctcagca gaatagcaaa aactttgctc aggacatttg aggtcaaatt gaagacggaa     2220

gacggaagac ggaaaccgga aaccgttttc ttgtaagccc ctagaggcag atcaggtaaa     2280

gcatacatag tagagggaaa ggagagaatg gaaataaaac tgaatattat gcagatttat     2340

gccttatttt ttagcatttt ttaaggttgg gtctttcagg ctggttttgg tttgtattag     2400

atctgtatag tttaactagt gatttagttt tatatttaag ctacgattaa tattttttct     2460

ttggcgatat ttctttgctt tttttttttt taacaacttt ccatttttag atgtttcgtt     2520

gaatctattt agagcttcac catggcaata tgtatttccc ttaaaacact gcaaacaaat     2580

atactaggag tgtgcccttt taatctttac tagttattgt gagattgctg tgtaagctaa     2640

taaacacatt tgtaaataca ttgtttgcag gaagaaaact tcgagttaca ggtcaggaaa     2700

agcctgctga atttatgttg taaacgttac ttaacacagt ataaagatga aaagacaaca     2760

aaagtatctt catacttcct catcccctca ttgcaacaaa accttaaact gggagaacct     2820

tagtcccctc tctttcctct tcctcctcca cttcccactt attgtcactt tgtaatattc     2880

agagagcact tggattatgg atctgaatag agaaatgctt acagataatc attagcccac     2940

ataccagtaa cttatactta aagatgggat ggagttataa agtgctttta taatacaata     3000

taattgctaa aggcaagggt tgactctttg ttttattttg acatggcatg tcctgaaata     3060

aatattgatt cactatg                                                    3077


<210>  1645
<211>  2423
<212>  DNA
<213>  homo sapiens

<400>  1645
aggcgggagg gcgcgcgcca gggtcgctcg ctcgctccct ccctccgctg gtgcgtttag       60

tcagtcagcc agcagcagcc ggcgggcccg cgagccgcag agggcccgag cctcggacgc      120

cggcgcctcc tcctgccatt gttcgtcggg ctgcagcagt ggcgggcgca ggagcccggc      180

cccggagcca ccgcaacatc atgacaacag agaagagttt agtgactgag gccgaaaatt      240

cacagcacca acagaaggaa gagggtgagg aagccataaa ctcaggccaa caagaacctc      300

agcaggagga atcttgtcaa acagcagctg aaggagataa ttggtgtgaa cagaagctga      360

aagcttctaa tggagacact cctacacatg aagacttgac caagaacaag gagcggacat      420

cagaaagcag aggactttca cgactattct cctcgtttct caaaaggccc aaatctcagg      480

tgtccgagga agaaggcaaa gaagtagagt cagataaaga aaaaggtgaa ggaggtcaga      540

aagagataga atttggaacc agtcttgatg aagagatcat tttaaaggcc ccaattgcag      600

ctcctgaacc ggaactcaaa acagacccat ctttggatct tcattcatta agcagtgcag      660

aaacacagcc tgctcaggaa gaactcagag aagatccaga ttttgaaatt aaggaaggag      720

aaggacttga agagtgctcc aaaatagaag taaaagaaga aagccctcaa tcaaaagcag      780

aaacagaatt aaaagcttcc caaaaaccaa tcagaaaaca caggaacatg cactgcaagg      840

tttctttgtt ggatgacaca gtttatgaat gtgttgtgga gaaacatgct aagggacaag      900

atttgcttaa acgagtatgt gagcatctca atcttttgga agaagactat tttggtctag      960

ccatttggga taacgcaacc tctaagacat ggctggattc cgccaaagaa ataaaaaagc     1020

aggttcgtgg tgtcccttgg aattttacat ttaatgtaaa gttttatcca cctgacccag     1080

cacagttaac agaagacata acaagatatt atttatgtct tcagcttcgg caggacatag     1140

ttgcaggacg tctgccctgt tcctttgcaa ccttagcatt attaggttct tacaccatcc     1200

agtctgaact gggagactac gacccagaac tccatggcgt ggattatgtt agtgatttta     1260

aactggcccc gaatcagacc aaggaacttg aagagaaggt catggaactg cataagtcat     1320

acaggtccat gactccagct caggctgact tggagtttct tgagaatgcc aaaaagttgt     1380

ctatgtatgg agttgatctt cataaagcaa aggacttgga aggagtagat atcatcctag     1440

gtgtctgctc tagtggcctt ctggtttaca aagataagct gagaattaac cgcttccctt     1500

ggcccaaagt gctgaagatt tcttataaac gtagtagctt tttcatcaag attcggcctg     1560

gagagcaaga gcagtatgaa agtaccatcg gattcaaact tcccagttac cgagcagcta     1620

agaaattatg gaaagtctgt gtagaacatc acacgttttt cagattgaca tctacagaca     1680

ccattcccaa aagcaaattt cttgcgctag gatccaaatt tcgatacagt ggccggactc     1740

aagctcagac caggcaagct agtgctctaa ttgacaggcc tgccccacac ttcgagcgta     1800

cagcaagtaa acgggcgtcc cggagcctcg atggagcagc agctgtcgat tcggcagacc     1860

gaagtcctcg gcccacttct gcacctgcca ttactcaggg tcaggttgca gaaggtggcg     1920

tcctagatgc ctctgctaaa aaaacagtgg tccctaaagc acagaaggaa acagtgaagg     1980

ctgaagtgaa aaaggaagac gagccacctg agcaagctga gccagagccc acagaagcat     2040

ggaaggtgga aaaaacccac atcgaggtga cagtacccac ctcaaatggt gaccaaacac     2100

agaaaaagag agaaagacta gatggtgaaa acatttatat cagacatagc aatttaatgt     2160

tggaggattt agacaagagt caagaggaga tcaaaaaaca tcatgccagc atcagtgagc     2220

tgaaaaagaa cttcatggag tctgtaccag aaccacggcc tagtgaatgg gataaacgct     2280

tatccactca ctcacccttc cgaactctta acatcaatgg gcaaatcccc acaggagaag     2340

gagtgagtac tttgtccaca tgaccaattg tgaaaatgga gggaataaat gtttttatgt     2400

attaaaaaaa aaaaaaaaaa aaa                                             2423


<210>  1646
<211>  5999
<212>  DNA
<213>  homo sapiens

<400>  1646
agttgccctg tcagtgcagg tggaggcccc ggcggggcaa agtggcagga acctcttaaa       60

gggcgagagc ggcgcggagc cagaacgcgg tcggcccggt ccccgccgca cccagcccag      120

caacatcatg acaacagaga agagtttagt gactgaggcc gaaaattcac agcaccaaca      180

gaaggaagag ggtgaggaag ccataaactc aggccaacaa gaacctcagc aggaggaatc      240

ttgtcaaaca gcagctgaag gagataattg gtgtgaacag aagctgaaag cttctaatgg      300

agacactcct acacatgaag acttgaccaa gaacaaggag cggacatcag aaagcagagg      360

actttcacga ctattctcct cgtttctcaa aaggcccaaa tctcaggtgt ccgaggaaga      420

aggcaaagaa gtagagtcag ataaagaaaa aggtgaagga ggtcagaaag agatagaatt      480

tggaaccagt cttgatgaag agatcatttt aaaggcccca attgcagctc ctgaaccgga      540

actcaaaaca gacccatctt tggatcttca ttcattaagc agtgcagaaa cacagcctca      600

ccattacaat taagaattat tttcagagtc ttcttatttc tgaagcatgt gaatattatc      660

tgcatcgtta aaagtcctgc tcaggaagaa ctcagagaag atccagattt tgaaattaag      720

gaaggagaag gacttgaaga gtgctccaaa atagaagtaa aagaagaaag ccctcaatca      780

aaagcagaaa cagaattaaa agcttcccaa aaaccaatca gaaaacacag gaacatgcac      840

tgcaaggttt ctttgttgga tgacacagtt tatgaatgtg ttgtggagaa acatgctaag      900

ggacaagatt tgcttaaacg agtatgtgag catctcaatc ttttggaaga agactatttt      960

ggtctagcca tttgggataa cgcaacctct aagacatggc tggattccgc caaagaaata     1020

aaaaagcagg ttcgtggtgt cccttggaat tttacattta atgtaaagtt ttatccacct     1080

gacccagcac agttaacaga agacataaca agatattatt tatgtcttca gcttcggcag     1140

gacatagttg caggacgtct gccctgttcc tttgcaacct tagcattatt aggttcttac     1200

accatccagt ctgaactggg agactacgac ccagaactcc atggcgtgga ttatgttagt     1260

gattttaaac tggccccgaa tcagaccaag gaacttgaag agaaggtcat ggaactgcat     1320

aagtcataca ggtccatgac tccagctcag gctgacttgg agtttcttga gaatgccaaa     1380

aagttgtcta tgtatggagt tgatcttcat aaagcaaagg acttggaagg agtagatatc     1440

atcctaggtg tctgctctag tggccttctg gtttacaaag ataagctgag aattaaccgc     1500

ttcccttggc ccaaagtgct gaagatttct tataaacgta gtagcttttt catcaagatt     1560

cggcctggag agcaagagca gtatgaaagt accatcggat tcaaacttcc cagttaccga     1620

gcagctaaga aattatggaa agtctgtgta gaacatcaca cgtttttcag attgacatct     1680

acagacacca ttcccaaaag caaatttctt gcgctaggat ccaaatttcg atacagtggc     1740

cggactcaag ctcagaccag gcaagctagt gctctaattg acaggcctgc cccacacttc     1800

gagcgtacag caagtaaacg ggcgtcccgg agcctcgatg gagcagcagc tgtcgattcg     1860

gcagaccgaa gtcctcggcc cacttctgca cctgccatta ctcagggtca ggttgcagaa     1920

ggtggcgtcc tagatgcctc tgctaaaaaa acagtggtcc ctaaagcaca gaaggaaaca     1980

gtgaaggctg aagtgaaaaa ggaagacgag ccacctgagc aagctgagcc agagcccaca     2040

gaagcatgga aggtggaaaa aacccacatc gaggtgacag tacccacctc aaatggtgac     2100

caaacacaga aaaagagaga aagactagat ggtgaaaaca tttatatcag acatagcaat     2160

ttaatgttgg aggatttaga caagagtcaa gaggagatca aaaaacatca tgccagcatc     2220

agtgagctga aaaagaactt catggagtct gtaccagaac cacggcctag tgaatgggat     2280

aaacgcttat ccactcactc acccttccga actcttaaca tcaatgggca aatccccaca     2340

ggagaaggac ctcccctggt gaagacacaa actgtcacca tctcagataa tgccaatgct     2400

gtgaaaagtg aaatcccaac caaagacgtc cctattgtcc acactgagac caagaccatc     2460

acttatgagg ctgcccagac tgacgacaac agtggagact tggacccagg agtcttgctg     2520

acagctcaaa ctatcacatc tgagacccca agcagcacca ccacaactca aattaccaag     2580

actgtaaaag gtgggatttc agagacacgt attgaaaaga gaattgtgat cacaggagat     2640

gctgatattg accatgatca ggtccttgta caagccatca aggaggcaaa ggagcagcac     2700

ccagacatgt cagtgaccaa ggtggtcgtc caccaggaga ccgagattgc tgatgagtga     2760

gctcaggaac taacctaccc caactctgcc cttctcccat ccaagagaaa ccagcaaaat     2820

gataaagaag ctaacctgcc atagtcagac ttcagacttt caagattatt ctaaatcacc     2880

agaaaattaa tttcagtttc tattgggagt ttataccaag agattcttct agatctcatt     2940

gatccttttg aagagctttt tctatattag gatatcagaa ttgttcaact tttcactcta     3000

tagactgttt taagagtttt ggggtttttt taattgggtg gtttgtaacc ccttcagcct     3060

agcctctctg cccatttatt tccaacccca acagacactg acagggtcca tggaattctt     3120

cgggaaatcc tccaaggact cttgtcagct gtgttggaag ccaaagccag cttagtggga     3180

cttccgcgtc tctccctagt cttatcccct ttggatgatg gcagaaactt catgaaccag     3240

ccctttctca gagccagtga tgtgagtgta tcagaatgcc agggagggca ccagccctga     3300

tccacagacc tcggaaagat gcccctgttc ctttgttgcg ggtggttttg gtaaggcaga     3360

gccctctgct gagaatgtag tattgttttt cccctctccc tcctgctttc tttttggagc     3420

ttctttgggt caaagacatg gaagttgctt cagatatctg atactgtgaa tgtttgaaca     3480

tatccgtggc cttcacctct ccagctaccc ttttacctca tcagaagcag tggctcagct     3540

aagtgctccc cctagctccc atctcaggag accaaatctc acagaaaaat aggcactttg     3600

ggccaaaagc tctaatggaa catttttagt ggtgatttgg ggaaggaaag ttaatgaggt     3660

ttttaaaata aggttttcta gttttgagag tgtgcacttc acacagggga atggggttac     3720

ttctgtctga tcctgggcct ttctttcatc ccaaatgaca aggaatgtgg ctcagagaag     3780

ggtttttctt ttttgacctt tcttctctca acaggaacct gcctgaggac acccttctag     3840

agcaaggaat tgacttttag gagccgttct ccccacaaga caccacatga caaggggtat     3900

aagccccagc cctgctcatt cccactcacc agctgaggtc tgtcaggttt tgaaggcttg     3960

attttgtggt gggtttgggg cttagttttc ctttttttca ttttgatttt tgaaagtgaa     4020

gatgatgccc taattcctgg taaggatttg gggcatagtt ttttgttttt ttgagacgga     4080

gtttcgctct tgttgcccaa gctggagtgc agtggcgcga tctcggctca ctgcaacctc     4140

cgcctcctgg gttcaagcag ttctcttgcc tcagcctccc aagtagctgg gatgacaggc     4200

gcacaccacc acgcccagca aattttttgt atttttagta gaaacgggat ttcaccttgt     4260

taggctggtc tcgaactcct gacctcaggt gatccaccca ccttggcctc ccaaagtgct     4320

gggattacag gtgtgagcca ccacgcccgg ccgatttggg gcatttttat ttaacagaac     4380

ttctctaacc ttccaactgc ttcccacaaa cacattggcc tcaaggctcc ttagaatccc     4440

agttccagct tcctaaaata gacagtgggt atcgggcagc agtcactggg gctcaagggc     4500

agtgagcaag agaaatgtct aaagctgctt ctcccaacac cgtccaaagt ctccactgcc     4560

tgagttttgt ttcggctggt ttgaactcat ttcgggtgtg tgcatttttc ttttggtacc     4620

catgtgagac atgaacaaca ggagggaggg aaagagccca ggtgggacgt gggacaggct     4680

taggggaaag agcttgtcct atctcaggaa caaaattata ggctgtgggc agagggtctg     4740

aaaggtgggc tttggggtag tgcccaagcc tggtcgtgtt gccaggagtg gtgacaagaa     4800

atgcagctta catcaaacga acatgtagtg catgcccact gcctgatggc cagatggcct     4860

gtaggaagag ctaccagggc ttccagacct gtggaacgaa gaggatgggg aaaaggcaga     4920

gggcactgag tgtcccttta aaaactaacc cactgaatat tccgtgtgat ctagaacagt     4980

gtggcagctt tcacagcaca ggaccgttca tcgggggcct aaacgtttcc ctcagctctg     5040

tcaccaactc acttctctcg gcttcgttgt ctgtaaattg gatgaaaaga gctctaatgc     5100

ctttcaggct cttagaagcc atagatttgg acaagcccag caagatgggt gtccttccag     5160

gcctcttccc ctttcctcca tctctggcaa cagttcttgg ggtttggcaa ttgtttggat     5220

tttttttctt tctgcagttg tgtgtatgtg tgtttgtgtg aagaaaaaca gactctgtcc     5280

aggtagaaat ggtgaggagg gggaagagaa ttacatttcc agggtcagaa acttggcaac     5340

agttttccta gagtgactca gacacaccac agtaacaact ctcgctgcaa ttttatttta     5400

atttgagaaa taaagatttc ctccaagcca catgaggact ctggcaccca cccacaaagc     5460

aagacctgta tttataagcc gagggctcag ggagcctaac tgcgggaccc gtcagggccc     5520

cgtgacccat ccccgtcccc acccccccct ccaccgctgg gcccatcagt gtgtgttggg     5580

gggatgcttg gcagctgggg gtgaggagac aacaaacctc gggaactgga gccagagctg     5640

cggcctgact gacgcctttt gatgctcacg ggaaatttct gcccaggatc tcagccccag     5700

gctggttgtt tctacaaatc tctctcaaat gtattatttt ggtgacaaaa atgaaggagc     5760

tttgtaaatt ttttttaaaa ttatgaatca tatcaagtag ttgtttacat ttcttgaaaa     5820

aataggaact cgggcagcag aatcagattg gcagaatctt tagactacac aggcaataat     5880

caagtctgct gttttggcct ttcgtagtag aagtggttgt agtgtttaga tatctgtttg     5940

gtcttgcttc ttgtattgca tttttttcaa taaacaacaa caaaaagaac tctcaaaaa      5999


<210>  1647
<211>  4012
<212>  DNA
<213>  homo sapiens

<400>  1647
agcgggacag acgagcggga ggggcagcgt gcggggagct gggggcgggg cgcggccgca       60

gctccgtttc cggtggctcg tcgcgctcgc tcactccagc tgcagccact ctcgcccgtg      120

gctgcttcct ccatcctggt attttttgga gcttccatcc tggttcttcc aaagtgcccg      180

gacccaaaac aggaaagtgt tgcggagata ggaacatggg agagaaacaa tctgggtaac      240

atgaaagtga tgctggttgc taagggaagg caacttgatt ctgtgggaag ggctgtagct      300

gatccatccg ttgtctagat ttgagtatga gcacagtgga agaggattct gacacagtaa      360

cagtagaaac tgtgaactct gtgactttga ctcaggacac agaagggaat ctcattcttc      420

actgccctca gaatgaagcg gatgaaatag actcagaaga tagtattgaa cctccacata      480

aaaggctttg tttgtcctct gaggatgatc agagtattga tgattctact ccttgcatat      540

cagttgttgc acttccactt tcagaaaatg atcagagctt tgaagtgacc atgactgcaa      600

ccacagaagt agcagatgat gaggttactg aggggactgt gacacagata cagattttgc      660

agaatgagca actagatgaa atatctccct tgggtaacga ggaagtttca gcagttagcc      720

aagcatggtt tacaactaaa gaagataagg attctctgac taataaagga cataaatgga      780

agcaggggat gtggtccaag gaagaaattg atattttgat gaacaatatt gaacgctatc      840

ttaaggcacg cggaataaaa gatgctacag aaatcatctt tgagatgtca aaagacgaaa      900

gaaaagattt ctacaggact atagcatggg gtctgaaccg gcctttgttt gcagtttata      960

gaagagtgct tcgcatgtat gatgacagaa accatgtggg aaaatataca cctgaagaaa     1020

ttgagaagct caaggagaaa aaggcaattg ctgcctgttt ttttttcacc cacagacaac     1080

tgtggacccc aaaaaaaggc cacactttca aactttggct ctcaaagtat tgctgcccac     1140

aacttccaaa ccagtcaaat gggaagaaga agaatgaaga ataaatgatg aaattaaaag     1200

ggagaaaaca attgaaccaa atgctgattg gcagactctt gttttaggct ccggataaag     1260

catggcaatg actgggcaac aataggggcg gcgctaggaa gaagtgcatc ttctgtcaaa     1320

gatcggtgcc gactgatgaa ggatacttgc aacacaggga agtggacaga agaagaagaa     1380

aagagacttg cagaagtggt tcatgagttg acaagcactg agccaggtga catagtcaca     1440

cagggtgtgt cttgggcagc tgtggctgaa cgagtcggta cccgctcaga aaagcaatgt     1500

cgttctaaat ggctcaacta cctgaattgg aaacagagtg ggggtactga atggaccaag     1560

gaagatgaaa tcaatctcat cctcaggata gcagaacttg atgtagctga tgaaaatgac     1620

attaactggg atctgttagc tgagggatgg agtagtgtcc gttcaccaca atggctacga     1680

agtaaatggt ggaccatcaa aaggcaaatt gcaaaccata aggatgtttc gttccctgtc     1740

ttaataaaag gtcttaaaca gttacatgag aaccaaaaaa acaacccaac gcttttggag     1800

aataaatcag gatctggagt tccaaacagt aataccaatt ccagtgtgca gcatgttcag     1860

ataagagttg cccgcttgga agataataca gccatctctt ctagccccat ggcagcattg     1920

cagattccag tccagatcac ccatgtttct tcagcagact ctcctgctac cgttgactca     1980

gaaacaataa cactaaacag tggaacacta cagacatttg agattcttcc ctctttccat     2040

ctacagccca ctggcactcc aggcacctac ctacttcaaa caagctcaag ccaaggcctt     2100

cccctaactc tgactgctag tcccacagta accctgacag ctgctgctcc tgcttctcct     2160

gaacagatta ttgttcatgc tttatcccca gaacatttgt tgaacacaag tgataatgtt     2220

acagtgcagt gtcacacacc aagagtcatc attcagactg ttgccacaga ggacatcact     2280

tcttccatat cccaagcaga actgacagtc gatagtgata ttcagtcatc tgattttcct     2340

gagcctccag acgccctaga agcagacact ttcccagatg aaattcatca ccctaagatg     2400

actgtggagc catcatttaa tgatgctcat gtatccaaat tcagtgacca aaatagcaca     2460

gaactgatga atagtgttat ggtcagaaca gaagaagaaa tctctgacac cgaccttaaa     2520

caagaggaat caccctctga tttagccagt gcttatgtta ctgagggttt agagtctccc     2580

actatagaag aacaagttga tcaaacaatt gatgatgaaa caatacttat cgttccttca     2640

ccacatggct ttatccaggc atctgatgtt atagatactg aatctgtctt gcctttgaca     2700

acactaacag atcccatact ccaacatcat caggaagaat caaatatcat tggatcatcc     2760

ttgggcagtc ctgtttcaga agattcaaag gatgtcgaag atttggtaaa ctgtcattag     2820

aataattctt agaaataggc agttcaagca aagaaggcac actgttaatt acaacctctt     2880

caaagaaata ggagcaaccc ccaagaggct taatttacca atttaaatag ccacagtcct     2940

taagccacac acattgttgc tgctatgact ttttacctcc tttaaacaca tcatctgagg     3000

ttgagtttta tgacagtatg tagttgagtg gaggctggga gttttaagca taaatccctg     3060

tttagtgtta catgggaata aggaatttca ttcacttcag ccactaagaa aagtttagaa     3120

tcacgaaagc ttaactgctg tggtttaaag tacagtttct ctaaagatca gacatggcac     3180

tgtctcctct caagcctggt tgtagttcag atgagtcttt tcaacatggt cttcaacatg     3240

gtctagagct taccagtgat cttctgatct tcaagaagac taagtttgag acttgaccag     3300

catacaagta tagagaccta ggaggtggtc ttgtggtggt acatttggtt aacccattgc     3360

tggcagtggg agctgattta ggcagggtaa acaggaaagc attaaaagtt aaaattcact     3420

acaggttttt tgttactttt aaagggaata tggataagca tagtaacaaa acccaccaga     3480

atctaagcag ttttcacccc ctcagaaacc actgtcatta gtttacaaag ttagcacttt     3540

gaagtaaaac taaatgagga aggaagtaat gttacctatc cttgatacca tgaccattta     3600

ttagatgttt tgctatataa attaccgaga gaatagtttg tcatccactt agtgtgttag     3660

ctggtggggt acaatataac ctctcatctc aggctatttt aaaaaaacaa tatttgcttc     3720

tataacaaaa ggaaacaaat ctaagaatca ttcctgtact acagaagggt taaggcaaag     3780

gtagcctttt gggcttttta atgaatatga cccctataga aaagtcaaga aaaaaaaacc     3840

cttgtataaa ttattttatt tattattgta attagatctt cacaaagttg tcttttcact     3900

gtgttttgtc aacgtgaaat taaattgtag ttataagcaa aagttggttg cctagggaac     3960

aattgtatat tcagtttaac agaaataaaa gaatatttgt cttaagatgc aa             4012


<210>  1648
<211>  3973
<212>  DNA
<213>  homo sapiens

<400>  1648
agcgggacag acgagcggga ggggcagcgt gcggggagct gggggcgggg cgcggccgca       60

gctccgtttc cggtggctcg tcgcgctcgc tcactccagc tgcagccact ctcgcccgtg      120

gctgcttcct ccatcctggt attttttgga gcttccatcc tggttcttcc aaagtgcccg      180

gacccaaaac aggaaagtgt tgcggagata ggaacatggg agagaaacaa tctgggtaac      240

atgaaagtga tgctggttgc taagggaagg caacttgatt ctgtgggaag ggctgtagct      300

gatccatccg ttgtctagat ttgagtatga gcacagtgga agaggattct gacacagtaa      360

cagtagaaac tgtgaactct gtgactttga ctcaggacac agaagggaat ctcattcttc      420

actgccctca gaatgaagcg gatgaaatag actcagaaga tagtattgaa cctccacata      480

aaaggctttg tttgtcctct gaggatgatc agagtattga tgattctact ccttgcatat      540

cagttgttgc acttccactt tcagaaaatg atcagagctt tgaagtgacc atgactgcaa      600

ccacagaagt agcagatgat gaggttactg aggggactgt gacacagata cagattttgc      660

agaatgagca actagatgaa atatctccct tgggtaacga ggaagtttca gcagttagcc      720

aagcatggtt tacaactaaa gaagataagg attctctgac taataaagga cataaatgga      780

agcaggggat gtggtccaag gaagaaattg atattttgat gaacaatatt gaacgctatc      840

ttaaggcacg cggaataaaa gatgctacag aaatcatctt tgagatgtca aaagacgaaa      900

gaaaagattt ctacaggact atagcatggg gtctgaaccg gcctttgttt gcagtttata      960

gaagagtgct tcgcatgtat gatgacagaa accatgtggg aaaatataca cctgaagaaa     1020

ttgagaagct caaggaacaa ctgtggaccc caaaaaaagg ccacactttc aaactttggc     1080

tctcaaagta ttgctgccca caacttccaa accagtcaaa tgggaagaag aagaatgaag     1140

aataaatgat gaaattaaaa gggagaaaac aattgaacca aatgctgatt ggcagactct     1200

tgttttaggc tccggataaa gcatggcaat gactgggcaa caataggggc ggcgctagga     1260

agaagtgcat cttctgtcaa agatcggtgc cgactgatga aggatacttg caacacaggg     1320

aagtggacag aagaagaaga aaagagactt gcagaagtgg ttcatgagtt gacaagcact     1380

gagccaggtg acatagtcac acagggtgtg tcttgggcag ctgtggctga acgagtcggt     1440

acccgctcag aaaagcaatg tcgttctaaa tggctcaact acctgaattg gaaacagagt     1500

gggggtactg aatggaccaa ggaagatgaa atcaatctca tcctcaggat agcagaactt     1560

gatgtagctg atgaaaatga cattaactgg gatctgttag ctgagggatg gagtagtgtc     1620

cgttcaccac aatggctacg aagtaaatgg tggaccatca aaaggcaaat tgcaaaccat     1680

aaggatgttt cgttccctgt cttaataaaa ggtcttaaac agttacatga gaaccaaaaa     1740

aacaacccaa cgcttttgga gaataaatca ggatctggag ttccaaacag taataccaat     1800

tccagtgtgc agcatgttca gataagagtt gcccgcttgg aagataatac agccatctct     1860

tctagcccca tggcagcatt gcagattcca gtccagatca cccatgtttc ttcagcagac     1920

tctcctgcta ccgttgactc agaaacaata acactaaaca gtggaacact acagacattt     1980

gagattcttc cctctttcca tctacagccc actggcactc caggcaccta cctacttcaa     2040

acaagctcaa gccaaggcct tcccctaact ctgactgcta gtcccacagt aaccctgaca     2100

gctgctgctc ctgcttctcc tgaacagatt attgttcatg ctttatcccc agaacatttg     2160

ttgaacacaa gtgataatgt tacagtgcag tgtcacacac caagagtcat cattcagact     2220

gttgccacag aggacatcac ttcttccata tcccaagcag aactgacagt cgatagtgat     2280

attcagtcat ctgattttcc tgagcctcca gacgccctag aagcagacac tttcccagat     2340

gaaattcatc accctaagat gactgtggag ccatcattta atgatgctca tgtatccaaa     2400

ttcagtgacc aaaatagcac agaactgatg aatagtgtta tggtcagaac agaagaagaa     2460

atctctgaca ccgaccttaa acaagaggaa tcaccctctg atttagccag tgcttatgtt     2520

actgagggtt tagagtctcc cactatagaa gaacaagttg atcaaacaat tgatgatgaa     2580

acaatactta tcgttccttc accacatggc tttatccagg catctgatgt tatagatact     2640

gaatctgtct tgcctttgac aacactaaca gatcccatac tccaacatca tcaggaagaa     2700

tcaaatatca ttggatcatc cttgggcagt cctgtttcag aagattcaaa ggatgtcgaa     2760

gatttggtaa actgtcatta gaataattct tagaaatagg cagttcaagc aaagaaggca     2820

cactgttaat tacaacctct tcaaagaaat aggagcaacc cccaagaggc ttaatttacc     2880

aatttaaata gccacagtcc ttaagccaca cacattgttg ctgctatgac tttttacctc     2940

ctttaaacac atcatctgag gttgagtttt atgacagtat gtagttgagt ggaggctggg     3000

agttttaagc ataaatccct gtttagtgtt acatgggaat aaggaatttc attcacttca     3060

gccactaaga aaagtttaga atcacgaaag cttaactgct gtggtttaaa gtacagtttc     3120

tctaaagatc agacatggca ctgtctcctc tcaagcctgg ttgtagttca gatgagtctt     3180

ttcaacatgg tcttcaacat ggtctagagc ttaccagtga tcttctgatc ttcaagaaga     3240

ctaagtttga gacttgacca gcatacaagt atagagacct aggaggtggt cttgtggtgg     3300

tacatttggt taacccattg ctggcagtgg gagctgattt aggcagggta aacaggaaag     3360

cattaaaagt taaaattcac tacaggtttt ttgttacttt taaagggaat atggataagc     3420

atagtaacaa aacccaccag aatctaagca gttttcaccc cctcagaaac cactgtcatt     3480

agtttacaaa gttagcactt tgaagtaaaa ctaaatgagg aaggaagtaa tgttacctat     3540

ccttgatacc atgaccattt attagatgtt ttgctatata aattaccgag agaatagttt     3600

gtcatccact tagtgtgtta gctggtgggg tacaatataa cctctcatct caggctattt     3660

taaaaaaaca atatttgctt ctataacaaa aggaaacaaa tctaagaatc attcctgtac     3720

tacagaaggg ttaaggcaaa ggtagccttt tgggcttttt aatgaatatg acccctatag     3780

aaaagtcaag aaaaaaaaac ccttgtataa attattttat ttattattgt aattagatct     3840

tcacaaagtt gtcttttcac tgtgttttgt caacgtgaaa ttaaattgta gttataagca     3900

aaagttggtt gcctagggaa caattgtata ttcagtttaa cagaaataaa agaatatttg     3960

tcttaagatg caa                                                        3973


<210>  1649
<211>  4052
<212>  DNA
<213>  homo sapiens

<400>  1649
aagtaagtgc gatggaacct tcaggttcca accgccgcca gggccgctcc gcccagtgga       60

gcctgtccgg cccccttgct gcccgctagc tcccgccggc tggcgcaagc tgtcggcgcc      120

ggggcactgc gggcggggtc ggagcctggc cttcctgacg ttgcagctgc cgtccccgca      180

cgttccggcc agggcctccc tcttagggcc gggcggtgcc cgtggctcag gctgcagagt      240

agaaagcaca aaaaccagcc tgattgtatc tggaaaaaac cattatgtta cagttgatag      300

gctcacccca aaatatgctt ttggggactg atttagcacc tgcatattct gcgtgaatct      360

ctttaattgg ttgcagttga gctaatggtg gagccaaaat gctattgccc tgtcttcatc      420

aacatttaat caagtgttgc ggagatagga acatgggaga gaaacaatct gggtaacatg      480

aaagtgatgc tggttgctaa gggaaggcaa cttgattctg tgggaagggc tgtagctgat      540

ccatccgttg tctagatttg agtatgagca cagtggaaga ggattctgac acagtaacag      600

tagaaactgt gaactctgtg actttgactc aggacacaga agggaatctc attcttcact      660

gccctcagaa tgaagcggat gaaatagact cagaagatag tattgaacct ccacataaaa      720

ggctttgttt gtcctctgag gatgatcaga gtattgatga ttctactcct tgcatatcag      780

ttgttgcact tccactttca gaaaatgatc agagctttga agtgaccatg actgcaacca      840

cagaagtagc agatgatgag gttactgagg ggactgtgac acagatacag attttgcaga      900

atgagcaact agatgaaata tctcccttgg gtaacgagga agtttcagca gttagccaag      960

catggtttac aactaaagaa gataaggatt ctctgactaa taaaggacat aaatggaagc     1020

aggggatgtg gtccaaggaa gaaattgata ttttgatgaa caatattgaa cgctatctta     1080

aggcacgcgg aataaaagat gctacagaaa tcatctttga gatgtcaaaa gacgaaagaa     1140

aagatttcta caggactata gcatggggtc tgaaccggcc tttgtttgca gtttatagaa     1200

gagtgcttcg catgtatgat gacagaaacc atgtgggaaa atatacacct gaagaaattg     1260

agaagctcaa ggagctccgg ataaagcatg gcaatgactg ggcaacaata ggggcggcgc     1320

taggaagaag tgcatcttct gtcaaagatc ggtgccgact gatgaaggat acttgcaaca     1380

cagggaagtg gacagaagaa gaagaaaaga gacttgcaga agtggttcat gagttgacaa     1440

gcactgagcc aggtgacata gtcacacagg gtgtgtcttg ggcagctgtg gctgaacgag     1500

tcggtacccg ctcagaaaag caatgtcgtt ctaaatggct caactacctg aattggaaac     1560

agagtggggg tactgaatgg accaaggaag atgaaatcaa tctcatcctc aggatagcag     1620

aacttgatgt agctgatgaa aatgacatta actgggatct gttagctgag ggatggagta     1680

gtgtccgttc accacaatgg ctacgaagta aatggtggac catcaaaagg caaattgcaa     1740

accataagga tgtttcgttc cctgtcttaa taaaaggtct taaacagtta catgagaacc     1800

aaaaaaacaa cccaacgctt ttggagaata aatcaggatc tggagttcca aacagtaata     1860

ccaattccag tgtgcagcat gttcagataa gagttgcccg cttggaagat aatacagcca     1920

tctcttctag ccccatggca gcattgcaga ttccagtcca gatcacccat gtttcttcag     1980

cagactctcc tgctaccgtt gactcagaaa caataacact aaacagtgga acactacaga     2040

catttgagat tcttccctct ttccatctac agcccactgg cactccaggc acctacctac     2100

ttcaaacaag ctcaagccaa ggccttcccc taactctgac tgctagtccc acagtaaccc     2160

tgacagctgc tgctcctgct tctcctgaac agattattgt tcatgcttta tccccagaac     2220

atttgttgaa cacaagtgat aatgttacag tgcagtgtca cacaccaaga gtcatcattc     2280

agactgttgc cacagaggac atcacttctt ccatatccca agcagaactg acagtcgata     2340

gtgatattca gtcatctgat tttcctgagc ctccagacgc cctagaagca gacactttcc     2400

cagatgaaat tcatcaccct aagatgactg tggagccatc atttaatgat gctcatgtat     2460

ccaaattcag tgaccaaaat agcacagaac tgatgaatag tgttatggtc agaacagaag     2520

aagaaatctc tgacaccgac cttaaacaag aggaatcacc ctctgattta gccagtgctt     2580

atgttactga gggtttagag tctcccacta tagaagaaca agttgatcaa acaattgatg     2640

atgaaacaat acttatcgtt ccttcaccac atggctttat ccaggcatct gatgttatag     2700

atactgaatc tgtcttgcct ttgacaacac taacagatcc catactccaa catcatcagg     2760

aagaatcaaa tatcattgga tcatccttgg gcagtcctgt ttcagaagat tcaaaggatg     2820

tcgaagattt ggtaaactgt cattagaata attcttagaa ataggcagtt caagcaaaga     2880

aggcacactg ttaattacaa cctcttcaaa gaaataggag caacccccaa gaggcttaat     2940

ttaccaattt aaatagccac agtccttaag ccacacacat tgttgctgct atgacttttt     3000

acctccttta aacacatcat ctgaggttga gttttatgac agtatgtagt tgagtggagg     3060

ctgggagttt taagcataaa tccctgttta gtgttacatg ggaataagga atttcattca     3120

cttcagccac taagaaaagt ttagaatcac gaaagcttaa ctgctgtggt ttaaagtaca     3180

gtttctctaa agatcagaca tggcactgtc tcctctcaag cctggttgta gttcagatga     3240

gtcttttcaa catggtcttc aacatggtct agagcttacc agtgatcttc tgatcttcaa     3300

gaagactaag tttgagactt gaccagcata caagtataga gacctaggag gtggtcttgt     3360

ggtggtacat ttggttaacc cattgctggc agtgggagct gatttaggca gggtaaacag     3420

gaaagcatta aaagttaaaa ttcactacag gttttttgtt acttttaaag ggaatatgga     3480

taagcatagt aacaaaaccc accagaatct aagcagtttt caccccctca gaaaccactg     3540

tcattagttt acaaagttag cactttgaag taaaactaaa tgaggaagga agtaatgtta     3600

cctatccttg ataccatgac catttattag atgttttgct atataaatta ccgagagaat     3660

agtttgtcat ccacttagtg tgttagctgg tggggtacaa tataacctct catctcaggc     3720

tattttaaaa aaacaatatt tgcttctata acaaaaggaa acaaatctaa gaatcattcc     3780

tgtactacag aagggttaag gcaaaggtag ccttttgggc tttttaatga atatgacccc     3840

tatagaaaag tcaagaaaaa aaaacccttg tataaattat tttatttatt attgtaatta     3900

gatcttcaca aagttgtctt ttcactgtgt tttgtcaacg tgaaattaaa ttgtagttat     3960

aagcaaaagt tggttgccta gggaacaatt gtatattcag tttaacagaa ataaaagaat     4020

atttgtctta agatgcaaaa aaaaaaaaaa aa                                   4052


<210>  1650
<211>  7046
<212>  DNA
<213>  homo sapiens

<400>  1650
actacctttt ctcttcggtt ggctgtagtt taaattctaa ggtctcctca agaaatgaca       60

ttttcacatt tcttaggcat ctgtggtgcc agaggagcaa acccatcgca cacgccaggt      120

ctgccatggg gccctgggcg gtggggattt tggatgtaac gtgtctaggc cgagcccgcg      180

ccgtgaaagg cctaccctgc cgaaagcccg ggcggcgggc gcccacaagt cagggctcgg      240

tgcggcgccg cagccagctc tgcccgcgag ccgagtccgg gctgctgagg gggagccgcg      300

ctgggggcgg cggcgtcggg gcgggggcgg gagccgggcg gcagctccag cgcccgtggg      360

ggaggagcgg cagcggcggc ggctggagct gctgtggcga ccgacgcgag gcggtggcag      420

aggagaccca cccctgtcca catggacagt cgcaaaggcc tccgctgatg cattcacgcc      480

tgggcggggt gggcggacgg ccgtagcggc ggcggctgca gaacgagcta ggggcctggg      540

ggcgcctgac ggtcgcagag acctcgccgc tccggcgcgg cgggtgcggc cattttacgg      600

cctgggacga agggaggcgt gtttgtgtgc tcgctttcat tctcctttct tgggaaccca      660

cggctggggg aagtttctca ggcagcctgg gtgggcggtg gatggggagt cgtgggccga      720

gaggaaccgg gcccgggaag cgccgtcgtc gtcgtcgccg gtcgcgttcc cccggagagg      780

cctgagaagc tcgggccgcg ggcctcgctg cccgccagcc cgcggacagg cccgggcgcg      840

cctggcctgc ctttgtatag gcccgtctga acgtgggagc gcagcccgcc tgacggctga      900

gcccgaggcc cgcaaccctg cggcgtctac cctcctccgg cgcggcccct catcccggcg      960

agcacggcgg cggtgtgggc catggattaa gaaggaggcg gcgtgggagg aggaagatgg     1020

cggccggcaa gagcggcggt agcgcagggg agattacttt tctggaagct ttggctagat     1080

cagagtctaa gagagatgga ggttttaaaa ataattggag ctttgatcat gaagaagaaa     1140

gtgaaggaga tacagataaa gatgggacaa atctgctcag tgtggatgaa gatgaggatt     1200

ctgaaacctc aaaaggaaaa aagttaaatc gtcgatctga aattgttgct aatagctctg     1260

gtgaattcat cttgaagaca tatgtaagac gaaacaagtc tgaaagtttt aaaactttga     1320

aaggcaaccc aattggactt aacatgttga gcaacaataa gaaattgagt gaaaatacgc     1380

aaaatacgtc attatgttct ggaactgtag ttcatggtag acgttttcat catgctcatg     1440

cacagatacc agtagtaaaa acagcagccc aaagcagtct ggaccgaaaa gaaaggaaag     1500

aatacccacc tcatgtccaa aaagttgaaa ttaatcctgt aaggttaagt cggctccaag     1560

gtgttgaacg tataatgaag aaaacagaag agtccgaatc acaagtggag cctgaaatta     1620

agaggaaagt acaacagaaa cgacactgta gtacctatca gcctactcct cctctatctc     1680

ctgcttcaaa aaaatgttta acccatttag aggatttgca aagaaattgc agacaagcta     1740

ttactttgaa tgagtctact ggaccattat taagaacgtc aattcatcag aattctggag     1800

gacagaagtc acaaaacaca ggattaacaa ccaagaagtt ttatggcaac aatgtggaaa     1860

aggttccaat tgatattatt gtgaattgtg atgacagtaa acacacttat ttacagacta     1920

atggaaaagt cattttacct ggggcaaaaa tacccaaaat cacaaacttg aaagaaagga     1980

aaacaagttt gtcagaccta aatgatccaa tcattttgtc cagtgatgat gatgatgaca     2040

acgacagaac taacagaaga gaaagcatat ctcctcagcc tgctgattca gcatgttctt     2100

cccctgcacc atccactgga aaagtagaag cagcgctaaa tgaaaatact tgcagagcag     2160

agcgtgaact acgaagcatt ccagaagact cagagttaaa tacagttaca ttgccaagaa     2220

aagcaagaat gaaagaccag tttggcaatt ctattatcaa cacacctctg aaacgtcgta     2280

aagtgttttc tcaagaacct ccagatgctt tagctttaag ctgccaaagt tcctttgaca     2340

gtgtcatttt aaactgtcga agtatacgag taggaacact cttccggctg ttaatagagc     2400

ctgtaatttt ttgtttagat tttatcaaga tacagctaga cgaaccagac catgatcctg     2460

tagagattat attaaatacc tctgatctaa ctaaatgtga atggtgtaat gtccgaaaat     2520

tacctgtagt gtttcttcaa gcaattccag cagtttatca aaagctgagc atccaactgc     2580

aaatgaataa ggaggataaa gtttggaatg attgtaaagg agtaaataaa ttaacaaatt     2640

tagaagaaca atatataatt ttaatttttc aaaatggcct tgatcctccg gcaaatatgg     2700

tatttgaaag tatcattaat gaaattggta taaagaataa catctccaat ttttttgcga     2760

aaattccctt tgaagaagct aatggcagac ttgttgcctg tacaagaacc tatgaagaga     2820

gcatcaaagg aagttgtggg caaaaggaaa acaaaattaa aactgtatca tttgaatcta     2880

aaatacaact tagaagcaaa caagaatttc agttttttga tgaagaagaa gaaactggag     2940

aaaaccacac catcttcatt ggcccagtag aaaagttgat agtatatcca ccacctccag     3000

ctaagggagg catctctgtt accaatgagg acctgcactg tctaaatgaa ggagaatttt     3060

taaatgatgt tattatagac ttttatttga aatacttggt gcttgaaaaa ctgaagaagg     3120

aagacgctga ccgaattcat atattcagtt cttttttcta taaacgcctt aatcagagag     3180

agaggagaaa tcatgaaaca actaatctgt caatacagca aaaacggcat gggagagtaa     3240

aaacatggac ccggcacgta gatatttttg agaaggattt tatttttgta ccccttaatg     3300

aagctgcaca ctggtttttg gctgttgttt gtttccccgg tttggaaaaa ccaaagtatg     3360

aacctaatcc tcattaccat gaaaatgctg tcatacagaa atgttcaact gtagaggaca     3420

gttgtatttc ttcttcagcc agtgaaatgg agagttgttc acaaaactct tctgccaagc     3480

ctgtaattaa gaagatgcta aacaaaaaac attgcatagc tgtaattgat tccaatcctg     3540

ggcaggaaga aagtgaccct cgttataaga gaaacatatg cagtgtaaaa tacagtgtga     3600

aaaaaataaa tcatactgcg agtgaaaatg aagaattcaa taaaggagaa tctacatccc     3660

agaaagttgc tgataggact aaaagtgaga atggcctaca gaatgaaagt ttaagttcca     3720

cacatcatac agatggctta agcaaaatca gactaaacta tagcgatgaa tcacctgaag     3780

ctggtaaaat gcttgaagat gaactcgtcg acttctcaga agatcaggat aaccaggatg     3840

atagcagtga cgatggattc ctcgctgatg acaactgcag ttcagaaata ggacagtggc     3900

atttaaagcc tactatctgt aaacaacctt gtatcctact tatggactca ctccgaggcc     3960

cttctcggtc aaatgttgtc aaaattttaa gagagtattt agaagtggaa tgggaagtta     4020

aaaaaggaag caaaagaagt ttttccaaag atgttatgaa gggctctaat ccaaaagtac     4080

cacagcaaaa caacttcagt gactgtggtg tatatgtatt gcagtatgta gagagctttt     4140

ttgagaatcc aattctcagt tttgaactac ctatgaattt ggcaaactgg tttcctccac     4200

caagaatgag aacaaaaaga gaagaaatcc gaaacataat tctgaagcta caggaagatc     4260

agagcaaaga gaaaagaaag cataaggaca cttactcaac agaagcacct ttaggcgaag     4320

gaacagaaca atatgtcaat agtatctcag attgaccatt tctgttactt gtcatttcta     4380

ctttcagaaa ctaaatgact ttcaaatttg ggtatagaca ataaagaact gaagtgctca     4440

ctactcagtg atttggaaat tttgatgctt gtataaatgt cagataatta atttccaaag     4500

gcgtatgtat taagtaaaag tctgtaaata tgttaatgag gccaattttt ccagcattta     4560

taattatttt tttcacttgt taggaagctt ttgttatgta ttttctgtta atagtaccta     4620

aaattgcaac ttctaaacac aaataaaaag aaaatattta taggaggaaa tgattaattt     4680

gatattcttt agtgaacttg tttaattcct cagtgggtgt gacatatttc atgggaatat     4740

tcaaatatct atggtaatat tttgaccctt tatatttgtt ctaaaataag tcaaaatgtg     4800

aaaataatat taaatctaag atattttgaa ctaagcatct ttatatgctt gtgtaacagg     4860

aacaaagtaa cagcctttca attcatatac tgccttgtgt tcagtgaacc caagaaatgt     4920

aataaatatt tgtaatttta cacaaatatt taagaggaaa gagtattaag agcaattcaa     4980

aaaaagtaac cttatactac taaaaaaaaa attcttgcat atattatcat caaatgcatt     5040

tttgaagaca tcaaagactc aggttaaaac tattttggta agtgcagctt gaatttcaaa     5100

tatcccgtgt tacctttctc tattacagct taaagtatgc tacaatctgt gtcatatagt     5160

taattgataa gcatttttaa tctgtgtaaa cacaggaatt taaataggaa tttactattt     5220

ttttataaag cttttgctat tttttcattg ctcattttgt tcttattatt ttgataaagt     5280

atcagacttt ttgcttgagt tcttcagtgt aaattatttt ttacatgtaa aagtactgta     5340

ttcaaccagt tgcataatac agcaaaaatc tttgaattcc cctttaaaat aactaaaatt     5400

tgatggtttc catgacagat ttatagcaca tatagggatc ttgcatgtat ctgcagaaac     5460

ttcattattt ttcaaatgaa atggtgtata cttctttcaa atgaactttg agacttgaaa     5520

catattttag tcattttttg ttaaatattg aatttttaaa tacacatata tcaaaaatag     5580

ttgagaataa aaagaaagcc taatcatcag caattatttt atttttaatt tggccatctc     5640

tgacattgca gtcaatatct tagggtattt tcttgaattt aataaagtcc catgggtggg     5700

ttcagggtga atgggagtat taacaacaac caaaaaatat ctattgagac acagtagagt     5760

ctcagtaaga gaaatattaa aatgtaagaa aggtcaccat tagtgatatc aactgtagtt     5820

tgttactttg aactatattt ctgattaact ctttatagta ataacttaga gctgttagct     5880

cagatatctt aattagctca tatgaaaaac aagtttaatt ttattattta ctgaacatgg     5940

caaaatgctt ttcaatctat aataaaactg ggataaaaaa ttgaagttgt tttttttaaa     6000

acctaatagc aataagcaaa attggcatac ataatttttt taatgaacta tattttgtca     6060

gaatctgaag gtactgaaaa actattctaa aatgcctact tgtttttgca ttaatttgta     6120

atgcttacat tttgcaccct tagataatgt ttgataagat aaaaatataa tttatccctt     6180

gtaccaactc aagtcaatca gattttaaca tgaaaaatat agattaatgt atgtcagctt     6240

tctagaggta gaatactcag ctatttgatg gcatttttcc caccccatgt gaaattttat     6300

ttttggaagt tatgctagtg acattgcaat atatattgaa atcttcggag gctgccaggt     6360

tgagcttcaa aactagactt gagaatcttt cgtgtatatg cacattcact tgataattgt     6420

gtattctatg tagtttaaag tgggatcaag ccttttaaaa tgtgttatta gtacttagaa     6480

gttgtaaaac agaacttata gaggtttgtt actagacact gaaactgcat gacaagtatc     6540

tggtgtctta actaattaga tagatctgtt gtattggttt tcttgttgga tagaataaca     6600

gttaatcatt tttagaagag ttttagatta cttgccataa aatttgtatg tctcagctct     6660

tgttggttta ggagcagaag tggtgtttag tcccttcccg ttaatgttgc tgtgctactt     6720

cagacagctg aaaacttaat ggtattattt caagttcaca taaccctaaa aaaggttttc     6780

tttgtgtagt aacttgtgct taaactttta gtcaattaaa tgtaggaggt tttatttgaa     6840

aacataaaat gattctctaa attacatctt gttttaagcc accaaaatga atgcagtaat     6900

ttttctttaa aaaaatgatc tctgaaaact gtgagacaat gtaaaaagaa taagttttaa     6960

ttcccccaaa atcaaaaatt gtacttaaaa tctcagacaa ttcactgaac aggaataata     7020

aagaacatat tttaatatat aatatg                                          7046


<210>  1651
<211>  4060
<212>  DNA
<213>  homo sapiens

<400>  1651
acccaccccg tgagcagccc aaaccgacca ccgtcctccc ccagctccca ccaatcggat       60

cgcagggact cgagccccac actgctgagt ccgctgacac tgcgtccggg gccagacgac      120

gatatcagcg cggggtcccc acaacgccat ggggcagagc caactctcga gcgcgtgatc      180

gaagcccgca gttttttcgc ccccgtcact tccgggtgcg acaatctctt ctgtccggcc      240

agccgctgga gtcgttaggt gccgccttgc ttctgacgag ccacacgttt gcttcttccc      300

tgtgttccca gctggaggga catgagtgtc cctgggccgt cgtctccgga cggggccctg      360

acacggccac cctactgcct ggaggccggg gagccgacgc ctggtttaag tgacacttct      420

ccagatgaag ggttaataga ggacttgact atagaagaca aagcagtgga gcaactggca      480

gaaggattgc tttctcatta tttgccagat ctgcagagat caaaacaagc cctccaggaa      540

ctcacacaga accaagttgt attgttagac acactggaac aagagatttc aaaatttaaa      600

gaatgtcatt ctatgttgga tattaatgct ttgtttgctg aggctaaaca ctatcatgcc      660

aagttggtga atataagaaa agagatgctg atgcttcatg aaaaaacatc aaagttaaaa      720

aaaagagcac ttaaactgca gcagaagagg caaaaagaag agttggaaag ggagcagcaa      780

cgagagaagg agtttgaaag agaaaagcag ttaactgcca gaccagccaa aaggatgtga      840

aaagttgtgt ttgtgtgttt tcttctcctg tcccatattt gggttatgat gactcaagtg      900

tagactgaag ttgaggtagt gccttatgcc attatgtcat atgttgaaat ccttattccg      960

gtattactgt gtctccatgc cttttttcca agtagcagac gtcatgttgc atggtttttg     1020

atatttatat gtaagttttt caaattttgc ttaattttaa aatttattat tttgatcttg     1080

aattatttat aaactggaaa gtggtttgat tattgtgagt caaaactcta agtggttaaa     1140

aattagtatg aattttttag cttcttaatg aatatggatt taaaactctc cagttcttat     1200

tttatgaaat gacttgcctt tctggtaata caatgctgat tttttagtaa ttgccttttc     1260

attactttgt taagaagaaa tgccagctgt ttaatcacac ctacccctgg aaaagaggta     1320

aaccttttga acagttgaat ttcatcagaa gctctatagc tttttggtga gaggaagtga     1380

tactctttat tacaagaaac aaggaattaa caaaaataag gaacttgttg ctacctttct     1440

tttctgttga acattaaaaa taatttggtt tgtggactgg gcatggtggc ttatggaaaa     1500

gaggtgagcc tttgtgaaga acataatgga aaagtgcatg tacgggaaat aacagcactt     1560

taggtgtagt tcaggtgagc aagatgccag atagtttcta ctaaccatat actctttctg     1620

cttcttagcg tcgttgtcac tgcttctgtg gcttttgggt tcaaagtaga ttatatatat     1680

tcctaaagct tggtggaggt agtggagcta tcacacactc aaatgagctt gtatatttat     1740

aatacaatat agtattatag taacagttat catacactga gatatagttt ctgtgcttgt     1800

aaaaaattct tgaagtgagg ccgggtgcgg tggctcatgc ctgtaatccc aacgctttgg     1860

gacgccgagg cgggtggatc atgaggtcaa aagattgaga ccatcctggc caacatggtg     1920

aaaccccgtc tctactagaa atacaaaaat tagctgggtg tgggggcgtg cgcctgtagt     1980

cccagctact tgggaggctg aggcaggaga attgcttgaa cccaggaggc agaggttgca     2040

gtaagccaag atcgtgccac tgcactccag ccttggtgac agagcaagac tccgtctcca     2100

aaaaaaagaa aaaaaaattt cttgaagtgg aatgatgtac accaaatacc cactttatag     2160

ataattacag ggatggtgaa aaattagtaa atagcttcac aaaagaggca gcgtgatacc     2220

tttagtgttt tctagaattt ttttctggat attatatgta agaatttatt gtttgaggga     2280

aatacgaggt ttcattgttt aaaatcaaga gtgtattgtt tactgtttta cagtattatt     2340

taatatccaa ctggtctcca atctccatta catagggact gtacagagcc tgtgaagatg     2400

tatgaatggt atcttttata atccacaata catttctggt aagatggaat cactacctct     2460

gatcacatat caggctaacg atagagaaag cattaggttt aagttgaggg ctaagaactg     2520

gtttgtttaa aggtttaaat tgttggaaaa gagcatttgc cttctttaat gaatgatggt     2580

ctcacaattc agttgacttt gacctaatat ttaagaatat aaatatattt tatttgaaag     2640

gctgagtgtt gccctcaaac acttgctaaa actgcctagg gcaggattca ttagggcttg     2700

cagacaatgt cacctaaatt gctgaatgta ctcattataa tatgatatct gacaaaggta     2760

gtacagcgtt tctgagtcat ttgggaccaa ctgcagtggt tgtttaaaat gctggttcct     2820

gcacacaatt ctctatctac tgaagcacat ctgttttctt tgtttgtttt gctttgcttt     2880

ttgtttttaa agtttccccc agtgattcca gtgcacctga aaagttgaga accacaggct     2940

tagtggtacg ttggggtttc ccacgctagg ctgcatagca ttataacctg ggaacgttaa     3000

aaaaaataca gacattcttg attcttagtg tagttatgat gtggatccta cgtatttttt     3060

aaaaaactct ccagataatt ttgatgtcac gagtcactag tatagactat ctatctagtg     3120

agttgtatta taagcgatga aatactttaa aagctaccca gtaactcttg ggattaattt     3180

tatgaaataa attctgagct gctgcttttg atatagtcag acttaagact gaaccccagt     3240

agacaggcaa tagatataga attctggtta gctaattgaa cttttgtgac ctgtttaaaa     3300

acaaatcaaa tttattgaac aaatgacaag gcacaaatac tttcagaatt gtatttcagt     3360

tttgaagatt taaaaaaaat gtgaaaataa atatatatta gtatccttta ttttaaagtc     3420

aattgtaaac cagaagtact gttattttgg tgattaaaat ccaaaacttt agctgtattt     3480

cagtaacaaa aacatacctt actagactgt gatggctcac acctgtaatc ccagtgcttt     3540

gggaggctga ggtgggaaga ttctttgagc ccaggagttc aaggctgcag tgaattctga     3600

tcgcaccact gaactccagc ccgtatgaca gagtgagacc ctgtttctaa aaacaaaaca     3660

aacaaacaaa caaacaacgt atcttactga ctaaactgga atggaaatct tataattagt     3720

gttgtatttt tctgcaaaat agtgaattgg tacttgggag acttctgttc tttgttgaaa     3780

aaaattgcct ttgttttgaa attatatcac ctgtgttctg aactaaaatg atgggagttc     3840

attttgtatt tactttgcag taagtatcat gtaaatatgc aaatgttgaa tgtaatatag     3900

attgtgtcct cattgagttt ttgggtgata cagtttataa atataacaat tatacaccct     3960

catacattcg tctgattttg agcttgtaag atgagaactg ctttttacac atttaataaa     4020

aaaaggtctc tgaattatct gaaaaaaaaa aaaaaaaaaa                           4060


<210>  1652
<211>  4018
<212>  DNA
<213>  homo sapiens

<400>  1652
cagcggccga aaacttcagg ttccaggctg ctgtgcggct aaatgcgact ccatctcccc       60

cgacccaagc gcgtaatggc cgctggctat cttgggggag ccagctgttg gactatgccc      120

cactgccagg aaacaggcgc cggaaggttc tctgacaaga tctcgctttc ctagggcggt      180

gaaggcgttc aaaggtcggg aaggggcgct gggagaagcg gggcagcgct gagccatgct      240

cgcgaactgt gggtctgtct gtgaagagac ccagtttcgt gggaccacgg tggcgcctgc      300

gctgggaggt gagcttgtga cagagcgaaa actacaattc ccagcattcc tgtggtgcca      360

gaactacctt gcccgaaagc ctgtgcgaga tttaccccgt cttccgcctc cctcccaccg      420

gaaaactctg aggacatgaa tagtcgccag gcttggcggc tctttctctc ccaaggcaga      480

ggagatcgtt gggtttcaag gccccgcggg catttctcgc cggccctgcg gagagagttc      540

ttcactacca caaccaagga gggatatgat aggcggccag tggatataac tcctttagaa      600

caaaggaaat taacttttga tacccatgca ttggttcagg acttggaaac tcatggattt      660

gacaaaacac aagcagaaac aattgtatca gcgttaactg ctttatcaaa tgtcagcctg      720

gatactatct ataaagagat ggtcactcaa gctcaacagg aaataacagt acaacagcta      780

atggctcatt tggatgctat caggaaagac atggtcatcc tagagaaaag tgaatttgca      840

aatctgagag cagagaatga gaaaatgaaa attgaattag accaagttaa gcaacaacta      900

atgcatgaaa ccagtcgaat cagagcagat aataaactgg atatcaactt agaaaggagc      960

agagtaacag atatgtttac agatcaagaa aagcaactta tggaaacaac tacagaattt     1020

acaaaaaagg atactcaaac caaaagtatt atttcagaga ccagtaataa aattgacgct     1080

gaaattgctt ccttaaaaac actgatggaa tctaacaaac ttgagacaat tcgttatctt     1140

gcagcttcgg tgtttacttg cctggcaata gcattgggat tttatagatt ctggaagtag     1200

tattaatgct catcctgctg tggctgttgg cttcttagaa caccaaaccg ggagagattt     1260

actttgaaca ttgtcagttg cagcaaaaat ttactacaca agattattcg aagtgtatac     1320

ggactaaaag aggaagtgtt ttagaatgag aagagatact gtgtctttat tgtgtgtgtg     1380

tgagtgcagg tgtgtgtctt tattatattg aaaagctgtc actcagacct ggtttgagat     1440

agaagagcat tttgtccttt tgatagttaa tagaaattga accagagttt tcttatgttt     1500

gcttgaacag ttgtgtaaat catacaggat tttgtgggta ttggttgaat atttgtaaac     1560

cattccctag cctacatatt tattactgaa ttaactttcc tgataaccat tgcataatta     1620

catttttcta taaaatgaaa gattattaca acaaagttgt gtgggttttc aaagtgactt     1680

accatatagt tggagattga tttctttttg gtaatgaact aaaacaataa attttaaaat     1740

gataggccag gcgcggtggc tcacacctgt aatctcagca ctttgggagg ctgaggcggg     1800

tggatcactt gaggtcagga gttctagacc agcctggcca acatggtgaa accccgtctc     1860

tgctaaaaat acaaaaatta gccaggcatg gtggcacatg cctgtaattc cagctactcg     1920

ggaggctgag gcaggagaat cttgcagtga gccgagatag caccactgca ctccagcctg     1980

ggtgacagag caagactcca ttacctaaat aaataaatgt gtgctttagt gcaaattaca     2040

acacttaata tgaaatctgt agagttgcta aatattgagc tctgattatt acatgtattt     2100

tttaaatatt tgatactcaa aaaccagttt atccctgctt cttaatgtag tttaagttaa     2160

cccatcttaa atttattaca taaaacaaag cttttcttaa tgacttcaat tcagcaaaca     2220

ttgatatcta gtacctactc tcaagaaact cataggaaaa tttaaattcg tattttgttt     2280

tgttattaga tatatttttt cttacaaagt aatatctatt agtaaatcat atgtaatttc     2340

aaagaaattt taaaatatcc ttttcatctt agttcttcag tcttacccag atcaagaaga     2400

caagaccaga aagtaaacat tttgagttca taatgccttg gtaatagcta taaaagtttg     2460

acaatcatta ttcaaaatag ccttgtcatt tgtttagcta taaacaggga atctgcagta     2520

tagagcagtc aagagattgg tccatatggt ccagtgagtg agagtcaggc tttccaacta     2580

tattttcctc aaaaatctaa ctgctggttt gttttcaaaa gaaaaacctt gacattatcc     2640

tgttacattc tgattcattt ttatctctat tgcctaagag agttcttagt atattataga     2700

ttaattttca ctgagtcaat taataagtta ccatatatat taaagtccac tgtaacaaag     2760

tatactgcat ttgttcagtt aaccaatatg actgcctgct atatgccaaa cagcatgcta     2820

gtccctgtgt gcacagagat gaacatggtt tcattctcat tgaattgaca atcttaagga     2880

gagagacata aacaagtaaa ttattggttt gttaagattt aaaatattct aaaatattaa     2940

gagggaatgc gtctttcctc catgtgaagg aagctccagt agcataacac tgtcgtcact     3000

cttcatcccc ttatccactc tgccctaggt aaagtgactt gcccaattgt aaatctggaa     3060

ggagaaacaa ggtgcaatta gcccacttcc tccccactcc tgtttgggac cagcccatct     3120

gaagagacat tcattctgtt ctgcttctat gggatcaggc tctgcctctg caggatgagg     3180

cctggcccag tagagcaatg cttgagacag ggtaaatctg tccagttcta gagttcagtg     3240

ataagaagct tactggcctt aagatgaaac ccatattctc ttgctgagca cagtggcaca     3300

catctatagt cctagctgct tgggaggctg cggcagcagg attgcttgag ccaaggagtt     3360

catcaaggct aaagtgtacc atgatcatac ctataaatag tcactgcact ccagcctggc     3420

aacacatgag accctgtctc ctaaaaaaaa acttctccaa tagttttatc agcaaataaa     3480

ggtgtttttt aggcctctat attagtttat tcattcttca tcttagttat attcacaacc     3540

cagaatggaa aggaggtatg ccatttattg gaccttctca agccccaaca aataaatata     3600

cttattccca ggttatacag ccactaaata ttaaatagat ctgcgttctt tctcattgta     3660

ggggtttagc aaacaaagtg ctttgtatcc aataacagaa gaatagaaat atgcatacca     3720

taccctgtcc ccattacttt tagatcctat atcctttcca tgaaacttca ttttgatggt     3780

ggttctgggg ttcaggtaaa tttttgtttc agtgatggaa atatatgaaa taaggatgag     3840

aggattgtgt ttctatatgc cttaaaacta tacctctatt ccagcacttg cacttcacta     3900

tgaaacagca attatacgta tctttttcct acactaaact acaagttctc agaaggcctc     3960

tagacacatg tgaggtactt gttaaacgcc tgtggaataa atgatactca taaatctc       4018


<210>  1653
<211>  3583
<212>  DNA
<213>  homo sapiens

<400>  1653
aagtgggcgc acagtggctt ccgggcccgg acgccatttc cagcggttgc tggttctgac       60

gggttgtagt ctgccaggac aatgagttat gactaccatc agaactgggg ccgtgatggg      120

ggtccccgca gctccggtgg gggctatgga ggggggccag cagggggtca tggaggtaac      180

cgaggctccg gaggaggcgg cggcggcgga gggggtggtc gaggcggcag gggccggcat      240

cccgggcacc tgaaaggccg cgaaatcggc atgtggtacg cgaaaaaaca ggggcagaag      300

aacaaggaag cggagaggca agagagagct gtagtacaca tggatgaacg acgagaagaa      360

caaattgtac agttactgaa ttctgttcaa gcgaagaatg ataaagagtc agaagcacag      420

atatcctggt ttgctcctga ggatcatgga tacggtactg aagtttctac taagaacaca      480

ccatgctcag agaacaaact tgacatccag gaaaagaagt tgataaatca agaaaaaaaa      540

atgtttagaa tcaggaacag atcatatatt gaccgagatt ctgagtatct cttgcaagaa      600

aatgaaccag atggaacttt agaccaaaaa ttattggaag atttacaaaa gaaaaaaaat      660

gaccttcggt atattgaaat gcagcatttc agagaaaagc tgccttcgta tggaatgcaa      720

aaggaattgg taaatttaat tgataaccat caggtaacag taataagtgg tgaaactggt      780

tgtggcaaaa ccactcaagt tactcagttc attttggata actacattga aagaggaaaa      840

ggatctgctt gcagaatagt ttgtactcag ccaagaagaa ttagtgccat ttcagttgcg      900

gaaagagtag ctgcagaaag ggcagaatct tgtggcagtg gtaatagtac tggatatcaa      960

attcgtctcc agagtcggtt gccaaggaaa cagggttcta tcttatactg tacaacagga     1020

atcatccttc agtggctcca gtcagacccg tatttgtcca gtgttagtca tatcgtactt     1080

gatgaaatcc atgaaagaaa tctgcagtca gatgttttaa tgactgttgt taaagacctt     1140

ctcaattttc gatctgactt gaaagtaata ttgatgagtg caacattgaa tgcagaaaag     1200

ttttcagaat attttggtaa ctgtccaatg atacatatac ctggttttac ctttccggtt     1260

gtggaatatc ttttggaaga tgtaattgaa aaaataaggt atgttccaga acaaaaagaa     1320

cacagatccc agtttaagag gggtttcatg caagggcatg taaatagaca agaaaaagaa     1380

gaaaaagaag caatatataa agaacgttgg ccagattatg taagggaact gcgaagaagg     1440

tattctgcaa gtactgtaga tgttatagaa atgatggagg atgataaagt tgatctgaat     1500

ttgattgttg ccctcatccg atacattgtt ttggaagaag aggatggtgc gatactggtc     1560

tttctgccag gctgggacaa tatcagcact ttacatgatc tcttgatgtc acaagtaatg     1620

tttaaatcag ttaaccagac acaggtgttt aaaagaaccc ctcctggtgt tcggaaaata     1680

gtaattgcta ccaacattgc ggagactagc attaccatag atgatgtcgt ttatgtgata     1740

gatggaggaa aaataaaaga gacgcatttt gatactcaga acaatatcag tacaatgtcc     1800

gctgagtggg ttagtaaagc taatgccaaa cagagaaaag gtcgagctgg aagagttcaa     1860

cctggtcatt gctatcatct gtataatggt cttagagcaa gtcttctaga tgactatcaa     1920

ctgccagaaa ttttgagaac tcctttggaa gaactttgtt tacaaataaa gattttaagg     1980

ctaggtggaa ttgcttattt tctgagtaga ttaatggacc caccatcaaa tgaggcagtg     2040

ttactctcca taagacacct gatggagctg aacgctttgg ataaacaaga agaattgaca     2100

cctcttggag tccacttggc acgattaccc gttgagccac atattggaaa aatgattctt     2160

tttggagcac tgttctgctg cttagaccca gtactcacta ttgctgctag tctcagtttc     2220

aaagatccat ttgtcattcc actgggaaaa gaaaagattg cagatgcaag aagaaaggaa     2280

ttggcaaagg atactagaag tgatcactta acagttgtga atgcgtttga gggctgggaa     2340

gaggctaggc gacgtggttt cagatacgaa aaggactatt gctgggaata ttttctgtct     2400

tcaaacacac tgcagatgct gcataacatg aaaggacagt ttgctgagca tcttcttgga     2460

gctggatttg taagcagtag aaatcctaaa gatccagaat ctaatataaa ttcagataat     2520

gagaagataa ttaaagctgt catctgtgct ggtttatatc ccaaagttgc taaaattcga     2580

ctaaatttgg gtaaaaaaag aaaaatggta aaagtttaca caaaaaccga tggcctggtt     2640

gctgttcatc ctaaatctgt taatgtggag caaacagact ttcactacaa ctggcttatc     2700

tatcacctaa agatgagaac aagcagtata tacttgtatg actgcacaga ggtttcccca     2760

tactgtctct tgttttttgg aggtgacatt tccatccaga aggataacga tcaggaaact     2820

attgctgtag atgagtggat tgtatttcag tctccagcaa gaattgccca tcttgttaag     2880

gaattaagaa aggaactaga tattcttctg caagagaaga ttgaaagtcc tcatcctgta     2940

gactggaatg acactaaatc cagagactgt gcagtactgt cagctattat agacttgatc     3000

aaaacacagg aaaaggcaac tcccaggaac tttccgccac gattccagga tggatattac     3060

agctgacagc ttttcagggg tggtctgaaa agccagtttg acagccattc ttcatcattg     3120

tttaaatttt ggctggatgc caaaccctgg gacatgaaca attttcatgt gtaaggtaga     3180

agccttcagt aggtagtaaa gacttaatgt gcatgacttg atgttatatg tagagatata     3240

tatatatata tatatatacc ataaaagcaa tatgttctct gatcatatac tctgctgtgg     3300

tcatgcccac tctttgggag tatattccct ttatatatat tgagtattgt accacttgag     3360

aaattccttt gttctgttat acaaaattaa tctttctgct cataatgatt gatgatacca     3420

ccagtaaaaa taggatgttt accccaaaac aagtgtcaat taagaatttg aacacaacca     3480

cattttttaa aatgaaactt ctatcggaag taaattaatt tgttgtaata aagtccagta     3540

tttaataaaa tgtacaatgt taaatctcaa aaaaaaaaaa aaa                       3583


<210>  1654
<211>  4709
<212>  DNA
<213>  homo sapiens

<400>  1654
ggcgcgttcc ttcctcttcc tctctcctct ccggccccgc cttcccttcc ctccgcccac       60

ctccctgaag cggagccgcc gtcgccacca gcgccgtcat gtcggccccc gccgggtcct      120

ctcacccggc cgccagcgcc cggatcccgc ccaagttcgg cggagcggcc gtctcaggag      180

ccgcagcgcc cgcgggcccg ggtgcgggcc cggcgccgca ccagcagaac ggtccagccc      240

agaatcaaat gcaggttcca tctggatatg gattgcatca tcaaaactat attgctccct      300

caggacatta ctctcaagga cctgggaaaa tgacctcatt gccattggat acccagtgtg      360

gtgattacta ctctgctctc tatacagtac caacacaaaa tgtgactcct aacacagtga      420

accagcaacc aggagcacag cagttgtaca gcaggggtcc tcctgcccct catattgtgg      480

gatccactct aggatctttc caaggtgctg catcgtcagc atcccatttg catacgagtg      540

cctcccaacc atactcctct tttgtgaatc actacaatag tccagccatg tactctgcca      600

gctcttctgt tgcgtctcag ggatttccct ctacttgtgg tcattatgct atgtcaactg      660

tttctaatgc cgcgtatcct agtgtttcat atccctctct gcctgctggt gatacatatg      720

ggcaaatgtt tacctcacag aatgctccga ctgttaggcc agttaaagat aattcattct      780

ctggtcaaaa tacagctatc agccatccat cgccacttcc acctctacca tcacaacagc      840

accaccagca gcaaagtctt tcaggataca gtactctaac gtggtcatct ccaggccttc      900

catcgactca agacaatctc atccgaaacc acacaggatc cctggctgta gcgaacaaca      960

acccaaccat tactgttgca gattctttat cctgtcctgt tatgcaaaat gttcagcctc     1020

ccaagtccag cccagtggta tccactgttt tatcaggatc ctcaggatcc tcatcaacaa     1080

gaacacctcc cactgcaaat cacccagttg agcctgtgac ctcagttaca cagccatcag     1140

agctattaca acaaaaaggc gtgcagtatg gtgaatatgt taataaccaa gctagctccg     1200

caccaactcc cttgtcatca acttccgatg atgaggaaga ggaggaggag gatgaggaag     1260

caggtgttga cagctcttct accacaagca gtgcttctcc aatgcccaac agttatgatg     1320

ccctggaagg aggcagttac ccagatatgc tttcttcatc agcaagcagt cctgctcctg     1380

atcccgcccc tgaacctgat cctgcttctg ctccagctcc agcttcagct ccagctcctg     1440

tcgtccctca gccttcaaaa atggctaagc cttttggcta tggctatcca acacttcagc     1500

ctggttatca gaatgctaca gcaccactta tttctggagt acagcccagt aacccggtat     1560

attctggatt ccagcagtat cctcaacagt atcctggtgt gaaccagcta tcctccagta     1620

taggaggatt gagtcttcag agttctccac aaccagaaag cctgagacct gtaaacctta     1680

ctcaggagag gaatatttta cctatgactc ctgtttgggc tcctgtacct aacttgaatg     1740

cagacctcaa aaaattaaac tgtagcccag attcatttcg gtgtactttg acaaatattc     1800

cacagacaca ggctttactg aataaagcta agcttccttt aggattgttg ttacatccct     1860

tcagagacct aacgcaatta ccagtgataa catcaaatac cattgtgagg tgccgatcct     1920

gtcgaacgta tattaacccc tttgtatcct tcattgatca acgtagatgg aaatgcaatt     1980

tgtgctatag agtaaacgat gttcctgaag aatttatgta taaccccctt acccgatctt     2040

atggagagcc tcataaacga ccagaagttc agaattcaac tgtggagttc attgcttctt     2100

cagattacat gctgcgtcct cctcaacctg cagtttactt gtttgtttta gatgtgtctc     2160

ataatgcagt ggaagctgga tatttgacaa ttttgtgcca gtcactccta gaaaatctag     2220

acaagcttcc tggagattca cgaacaagaa taggattcat gacctttgat agcactattc     2280

atttctacaa tttacaagaa ggattatcac agcctcaaat gttgattgtg tctgatatag     2340

atgatgtttt tctacctaca ccggatagtt tacttgtgaa tctatatgaa agtaaagagc     2400

ttataaaaga cttactgaat gcattaccaa acatgttcac caatacaaga gaaacacaca     2460

gtgcccttgg tcctgcactt caggctgcct ttaaattaat gtctccaaca ggtggccgtg     2520

tgtctgtatt tcagacacag ttaccttcct tgggtgcagg acttctgcaa tccagagaag     2580

atcctaatca gagatcaagt acaaaggtgg tacaacatct tggccctgca actgattttt     2640

ataagaaact tgcattagat tgctcgggac agcaaactgc agtggatttg ttccttttaa     2700

gttcacagta ttctgatctt gcttctctag cttgcatgtc caagtattct gcagggtgca     2760

tctattatta tccatcattc cactatactc acaatccttc acaagcagaa aagttacaaa     2820

aagacctaaa acggtatctc acaagaaaaa ttgggtttga agctgttatg agaataaggt     2880

gtactaaagg tctttcaatg cacacttttc acggtaactt ctttgtccgt tctactgatt     2940

tgttatccct tgccaacatc aatcctgatg ctggatttgc ggtgcagttg tcaattgaag     3000

aaagtttaac agatacttcc ttagtatgtt ttcaaacagc cctattatat acatcaagca     3060

aaggtgagcg gagaattaga gtacatacac tttgtttgcc agtggtaagt tcactagcag     3120

atgtatatgc gggagtggat gtacaagctg ccatctgcct tctggcaaac atggctgtgg     3180

atcggtccgt ttcatcaagt ctgtcagatg caagagatgc cttagtgaat gctgtagtgg     3240

actcattgtc tgcatatggc tcaactgtct caaatttaca gcactctgca ttgatggcgc     3300

ccagctccct caagttgttt cctctctatg ttttggccct tctcaaacag aaagcattta     3360

gaacgggtac aagcacacgg ctggatgatc gtgtatatgc catgtgtcag ataaagtctc     3420

agccacttgt tcatctaatg aaaatgattc atcccaactt atacaggata gacagattga     3480

cagatgaggg tgcagtacat gttaatgaca ggattgtacc acagccacct cttcaaaaat     3540

tgtctgcaga gaagctgaca agagaaggtg ctttccttat ggactgtggc tctgtttttt     3600

acatttgggt tgggaaaggc tgtgacaata acttcataga ggatgtgctt ggatatacta     3660

attttgcatc aataccacag aaaatgacac atcttccaga gctagataca ctttcatcag     3720

aaagagccag atccttcata acttggctta gagacagcag accattaagt ccaatccttc     3780

acatagtaaa agatgagagt cctgccaaag cagaattttt tcagcatttg attgaagacc     3840

ggacagaggc tgcattttct tactatgaat ttttgcttca tgttcagcag cagatttgta     3900

agtgaagtag aataaaattg aataagaaaa agatctataa cctaggtaaa gcataatctg     3960

tcagagaagc gcgtgagaaa tttgaaatga aggcatttgt taatacaaga tgcaacgcac     4020

agcactctgt ctgaggcttt ggtaaaaagt aaaggggaag aaagaacttg acagatcttt     4080

ttcaactcaa attaatggta acgatgatgc tgtttcacca agtatatttt gaattggttt     4140

ctacacattt ccagtagtat ggcagtacag tgctctgttc attgcaagct ggcaaattta     4200

tgtagctatg tggaatgata tgtcataatg taaaattaga taaattcttt tttcttataa     4260

ttaatataac atttctggac ttgaactctg gcaagagatg ccaaaaggca ttggtaccgt     4320

gttatttgtt tatatgaatt actttttaac aaggaatgtt tcttattcat taaatgaatt     4380

caacattttc tctgtaaaaa caatagagtt tcagtacatg aactatagaa aaaaatctat     4440

atataatgta cataaatgtt acatttgtaa agaaaatgta aaaatgtaac tatagcatat     4500

gaattgctta aactgtgctg cattgttgga tgacaactct ttttgtcaca gttagagaat     4560

gaggttgact aatgcatatt atgaattgag tccacaaagg aacacaaaac tctttgtaat     4620

tctgttaaat cttttatgta gatttattta tgatcagcct actaattaaa actatttcgc     4680

ttgacagtaa aaaaaaaaaa aaaaaaaaa                                       4709


<210>  1655
<211>  3495
<212>  DNA
<213>  homo sapiens

<400>  1655
agcgccggcg aggcgcggga ggaggagaag cagtggggag gcgcagccgc tcacctgcgg       60

ggcagggcgc ggaggaggga cccgggctgc gcgctctcgg gccgaggaac caggacgcgc      120

ccggagcctc gcacgcggcc aagctcgggg cgtcccctcc cctcggccgg gcgaactcaa      180

ggggcgcagc tctttgcttt gacagagctg gccggcggag gcgtgcagag cggcgagccg      240

gcgagccagg ctgagaaact cgagccggga acaaagaggg gtcggactga gtgtgtgtgt      300

cggctcgagc tccgggcaga ggcatttggg cccgaggccc ccgctgtgac tccccgagac      360

tccgcagtgc cctccactgc ggagtccccg cgcttgccgg caaaaacttt attcttggca      420

aacttctctt tctcttcccc tcctcctcgg cccccatctt ctgctcctcc tccttctcta      480

gcagattaaa tgagcctcga gaagaaaaac cgaagcgaaa gggaagaaaa taagaagatc      540

taaaacggac atctccagcg tgggtggctc ctttttcttt ttcttttttt cccacccttc      600

aggaagtgga cgtttcgtta tcttctgatc cttgcacctt cttttggggc aaacggggcc      660

cttctgccca gatcccctct cttttctcgg aaaacaaact actaagtcgg catccggggt      720

aactacagtg gagagggttt ccgcggagac gcgccgccgg accctcctct gcactttggg      780

gaggcgtgct ccctccagaa ccggcgttct ccgcgcgcaa atcccggcga cgcggggtcg      840

cggggtggcc gccggggcag cctcgtctag cgcgcgccgc gcagacgccc ccggagtcgc      900

cagctaccgc agccctcgcc gcccagtgcc cttcggcctc gggggcgggc gcctgcgtcg      960

gtctccgcga agcgggaaag cgcggcggcc gccgggattc gggcgccgcg gcagctgctc     1020

cggctgccgg ccggcggccc cgcgctcgcc cgccccgctt ccgcccgctg tcctgctgca     1080

cgaacccttc caactctcct ttcctccccc acccttgagt tacccctctg tctttcctgc     1140

tgttgcgcgg gtgctcccac agcggagcgg agattacaga gccgccggga tgccccaact     1200

ctccggagga ggtggcggcg gcggggggga cccggaactc tgcgccacgg acgagatgat     1260

ccccttcaag gacgagggcg atcctcagaa ggaaaagatc ttcgccgaga tcagtcatcc     1320

cgaagaggaa ggcgatttag ctgacatcaa gtcttccttg gtgaacgagt ctgaaatcat     1380

cccggccagc aacggacacg aggtggccag acaagcacaa acctctcagg agccctacca     1440

cgacaaggcc agagaacacc ccgatgacgg aaagcatcca gatggaggcc tctacaacaa     1500

gggaccctcc tactcgagtt attccgggta cataatgatg ccaaatatga ataacgaccc     1560

atacatgtca aatggatctc tttctccacc catcccgaga acatcaaata aagtgcccgt     1620

ggtgcagcca tcccatgcgg tccatcctct cacccccctc atcacttaca gtgacgagca     1680

cttttctcca ggatcacacc cgtcacacat cccatcagat gtcaactcca aacaaggcat     1740

gtccagacat cctccagctc ctgatatccc tactttttat cccttgtctc cgggtggtgt     1800

tggacagatc accccacctc ttggctggtt ttcccatcat atgattcccg gtcctcctgg     1860

tccccacaca actggcatcc ctcatccagc tattgtaaca cctcaggtca aacaggaaca     1920

tccccacact gacagtgacc taatgcacgt gaagcctcag catgaacaga gaaaggagca     1980

ggagccaaaa agacctcaca ttaagaagcc tctgaatgct tttatgttat acatgaaaga     2040

aatgagagcg aatgtcgttg ctgagtgtac tctaaaagaa agtgcagcta tcaaccagat     2100

tcttggcaga aggtggcatg ccctctcccg tgaagagcag gctaaatatt atgaattagc     2160

acggaaagaa agacagctac atatgcagct ttatccaggc tggtctgcaa gagacaatta     2220

tggtaagaaa aagaagagga agagagagaa actacaggaa tctgcatcag gtggaaaacg     2280

aagctcattc ccaacgtgca aagccaaggc agcgacccca ggacctcttc tggagatgga     2340

agcttgttga aaacccagac tgtctccacg gcctgcccag tcgaccccaa aggaacactg     2400

acatcaattt taccctgagg tcactgctag agacgctgat ccataaagac aatcactgcc     2460

aacccctctt tcgtctactg caagagccaa gttccaaaat aaagcataaa aaggtttttt     2520

aaaaggaaat gtaaaagcac atgagaatgc tagcaggctg tggggcagct gagcagcttt     2580

tctcccctca tatctgcgtg cacttcccag agcatcttgc atccaaacct gtaacctttc     2640

ggcaaggacg gtaacttggc tgcatttgcc tgtcatgcgc aactggagcc agcaaccagc     2700

acatccatca gcaccccagt ggaggagttc atggaagagt tccctctttg tttctgcttc     2760

atttttcttt cttttctttt ctcctaaagc ttttatttaa cagtgcaaaa ggatcgtttt     2820

tttttgcttt tttaaacttg aattttttta atttacactt tttagtttta attttcttgt     2880

atattttgct agctatgagc ttttaaataa aattgaaagt tctggaaaag tttgaaataa     2940

tgacataaaa agaagccttc tttttctgag acagcttgtc tggtaagtgg cttctctgtg     3000

aattgcctgt aacacatagt ggcttctccg cccttgtaag gtgttcagta gagctaaata     3060

aatgtaatag ccaaacccac tctgttggta gcaattggca gccctatttc agtttatttt     3120

ttcttctgtt ttcttctttt ctttttttaa acagtaaacc ttaacagatg cgttcagcag     3180

actggtttgc agtgaatttt catttctttc cttatcaccc ccttgttgta aaaagcccag     3240

cacttgaatt gttattactt taaatgttct gtatttgtat ctgtttttat tagccaatta     3300

gtgggatttt atgccagttg ttaaaatgag cattgatgta cccatttttt aaaaaagcaa     3360

ggcacagcct ttgcccaaaa ctgtcatcct aacgtttgtc attccagttt gagttaatgt     3420

gctgagcatt tttttaaaag aagctttgta ataaaacatt tttaaaaatt gtcatttaaa     3480

aaaaaaaaaa aaaaa                                                      3495


<210>  1656
<211>  3995
<212>  DNA
<213>  homo sapiens

<400>  1656
tggatatatg tcttggagag aggctgtgtg cattagctac aaatagtaac attttcaaaa       60

tcaacatgta ttgtgcttat cctgtccctg gaatgggcag caattctttg atgtattact      120

acaatgggaa aacggtatat gcaccatccc caaattcaga tgatttcaac cgtgaatctc      180

ctagttatcc atctcctaag ccaccaacca gtatgttcgc tagcactttc tttatgcaag      240

atgggaccca caattcttct gacctttgga gttcatcaaa tgggatgagc cagcctggtt      300

ttggtggaat tctggggacc tccacttccc acatgtctca atccagtagt tatggcaacc      360

ttcattcaca tgaccgcttg agttatcctc cacactcagt ttcaccaaca gacataaaca      420

cgagtcttcc accaatgtcc agctttcatc gcggcagtac cagcagttca ccttacgttg      480

ctgcctcaca cactcctccc atcaatggat cagacagcat tctaggaacc agagggaatg      540

ctgctggaag ctcacagaca ggtgatgcac ttggaaaggc tttggcatct atttattctc      600

ctgaccatac cagcagtagt tttccgtcaa atccatcaac accagttgga tcaccttcac      660

ctctcacagg taccagtcag tggccaagac ctggagggca agcaccttca tccccaagct      720

atgaaaactc actccactcc ctgcagtctc gaatggagga tcgtttagac agactggatg      780

atgcaatcca tgtgctgcgg aaccatgctg tgggaccttc caccagtttg cctgctggtc      840

acagtgatat acatagttta ttgggaccat cccataatgc accaattgga agcctcaatt      900

caaactatgg aggatcaagc cttgttgcaa gcagtcgatc agcttcaatg gttggaactc      960

atcgggaaga ctctgtcagt ctcaatggca atcattcagt cctgtctagt acagtcacta     1020

cttcaagcac agacctgaac cataaaacac aagaaaatta tagaggtggc ttgcaaagtc     1080

agtctggaac tgttgttaca acagaaatca agactgaaaa caaagaaaag gatgaaaacc     1140

ttcatgaacc tccttcatca gatgacatga agtcagatga tgaatcctcc caaaaagata     1200

tcaaggtttc atctagaggc agaacaagca gtactaatga agatgaggat ttgaaccctg     1260

aacagaagat agaaagggag aaggagaggc ggatggctaa caatgccaga gaacgcttac     1320

gcgtgcggga tattaatgaa gcattcaaag agcttggccg aatgtgtcag cttcacttga     1380

agagtgaaaa accccaaaca aaactcctta ttcttcatca agccgtggca gtcatcctta     1440

gtctagaaca gcaagtcaga gagaggaacc ttaaccccaa agcagcctgc cttaagagaa     1500

gggaagaaga aaaagtttct gccgtatcgg cagagccgcc aaccacactg ccaggaaccc     1560

atcctgggct tagtgaaact accaacccta tgggtcatat gtaaacatca gccagttcca     1620

gagttatcag taggctagat agaaggtgac ctctcctcat aaggacttgg acaactcaga     1680

ttatctgaag acacaaacct gacaggaggg agaagaaaaa acaaaacact tgaaccaaga     1740

aactcaaatg taatcctacg atcaaagcaa ctggtcaaca cttccatcag aagtgaagat     1800

aggaagctca tcagatagaa catcagccca tgagatgttt gcaacaaatc ttttgttgca     1860

agcagtgtgt cgcttctgca caatcagaga ctgtctcgat ctctccactc accgtggaag     1920

ttgccttgtg cctaaactga attgacaaat gcattgtaac tacaaatttt atttattgtt     1980

atgaaactgt aaggtctaca tataaaggga aaaagttaat gtggaaagct gatctacact     2040

cagctgatgc cagcatacat taaagcggtt cacgtgcaga gaacaaagca gtgacaacca     2100

ttggccctta gcattcccgg catacctatt agtgtcttaa aaaggaaggg aaaagtcttt     2160

tgttgccctc tcctatcctc ttgccatatg aatagcgttt tccatgaaat aggaaaatat     2220

tacttggtat agcatttctc ttgctctcat tttttgattt atttttattt tctctttgtg     2280

ggtgttatat ttgatctcta aatctgaaca gtttatggtc acagtccagc ctcctccgtg     2340

cagccctgtg tgctttgcac atttacctta cagtggtaag cagagaccat ctgtgaccat     2400

agcctagcta gcattttaaa aggggaaatt ttgttctcta ggttttcccc caaataaaca     2460

ttgctttatt tctaataata accaagactt ttcaagcttc tagatctcat aggaaagctt     2520

gtaatagcaa aattgtaaat tacaagggaa gaatctactt tttagaaatc gctttgtttt     2580

ccaagcagta agtactacat acagtacttg taaagtgtta gctgtaagta agcacaaaat     2640

acatttaaaa tacaaagacg attttttcag gctgtgatta tggtgaacat aacaaaaccc     2700

agtagtcacc aaggcaggta gtgtgataaa tgaacacacc actctgaggc taattaccta     2760

atggaataca agagcaatgg tcacccgtat ttccttatcc tagcctttat ttctctgtca     2820

tttggatggc tggtcaatgg ggaagaattg agtgggtgat ttaatcaact gcaaaccatc     2880

tgcccctgtc ccaaaatgat gagccagatt agcattaaac cagtacttgt cagtccatct     2940

taatactgtt cattaaggca ctctctgtct ctaatcctta ggagttgttt taaaagacat     3000

aatcactttg aacttccatg aaacctgtct tccaccacaa caaccctggg agagaaaaac     3060

atgctaaagg aggtatcttg gcttaataat tccttatagc caatatcaac agtggcaatc     3120

agcacacaga ggaaaggacc caaatcacta tgtagcttaa agatttctgt taatttgaaa     3180

gaacaaaaac aagacagaac ttctggtact ctaatcagga tgattcctaa caagtcagtc     3240

atttgtgaac ttagtggact ttttggttac tttaatttgc atatattctc cagttacatc     3300

ggactctatc tgtggccttg ttcttcattt cagtgttaat cagctaaaca gaagttgttg     3360

cttatgatgt gtgagtgaac atatgccact gcctggcctt tttttcttca gagcttgttg     3420

tctttttcgc tatattagac tttgcagtat gcccagaagc tttccttcat aaaatagaaa     3480

gaaaaaaaca tttggcttat ttttcactgt agctagtctt ttatacaata atcttgtaag     3540

aaaatttctt gaattctaaa tattactctt tctagatttt tgaaatcaaa aagttttcag     3600

taaaaagttt cttactttat tttattatat taggtagtaa aaaatgtagg gttatttacc     3660

ataacctgtt cattaatatc agaaatttac aatagcattt taagaccata gtaggattct     3720

agcataccgt gtagtaccta tggagtattg taagagctaa ttgttggaga tgaattgctt     3780

ctcatcttgt tctccagttt ccattgttgg tttattgcag atttgtatcc tgtgtcaaat     3840

tcaaggtatt attgataaac cttttcaacc agcagcaaga agttcaaatt tttttctgtc     3900

actgtaacag aaaacacaat atgtatataa catttatgta gcaataaatg tgccatcttt     3960

tttttaacac agtaaaaaaa aaaaaaaaaa aaaaa                                3995


<210>  1657
<211>  2177
<212>  DNA
<213>  homo sapiens

<400>  1657
cgaacgcctt cgcgcgatcg ccctggaaac gcattctctg cgaccggcag ccgccaatgg       60

gaagggagtg agtgccacga acaggccaat aaggagggag cagtgcgggg tttaaatctg      120

aggctaggct ggctcttctc ggcgtgctgc ggcggaacgg ctgttggttt ctgctgggtg      180

taggtccttg gctggtcggg cctccggtgt tctgcttctc cccgctgagc tgctgcctgg      240

tgaagaggaa gccatggcgc tccgagtcac caggaactcg aaaattaatg ctgaaaataa      300

ggcgaagatc aacatggcag gcgcaaagcg cgttcctacg gcccctgctg caacctccaa      360

gcccggactg aggccaagaa cagctcttgg ggacattggt aacaaagtca gtgaacaact      420

gcaggccaaa atgcctatga agaaggaagc aaaaccttca gctactggaa aagtcattga      480

taaaaaacta ccaaaacctc ttgaaaaggt acctatgctg gtgccagtgc cagtgtctga      540

gccagtgcca gagccagaac ctgagccaga acctgagcct gttaaagaag aaaaactttc      600

gcctgagcct attttggttg atactgcctc tccaagccca atggaaacat ctggatgtgc      660

ccctgcagaa gaagacctgt gtcaggcttt ctctgatgta attcttgcag taaatgatgt      720

ggatgcagaa gatggagctg atccaaacct ttgtagtgaa tatgtgaaag atatttatgc      780

ttatctgaga caacttgagg aagagcaagc agtcagacca aaatacctac tgggtcggga      840

agtcactgga aacatgagag ccatcctaat tgactggcta gtacaggttc aaatgaaatt      900

caggttgttg caggagacca tgtacatgac tgtctccatt attgatcggt tcatgcagaa      960

taattgtgtg cccaagaaga tgctgcagct ggttggtgtc actgccatgt ttattgcaag     1020

caaatatgaa gaaatgtacc ctccagaaat tggtgacttt gcttttgtga ctgacaacac     1080

ttatactaag caccaaatca gacagatgga aatgaagatt ctaagagctt taaactttgg     1140

tctgggtcgg cctctacctt tgcacttcct tcggagagca tctaagattg gagaggttga     1200

tgtcgagcaa catactttgg ccaaatacct gatggaacta actatgttgg actatgacat     1260

ggtgcacttt cctccttctc aaattgcagc aggagctttt tgcttagcac tgaaaattct     1320

ggataatggt gaatggacac caactctaca acattacctg tcatatactg aagaatctct     1380

tcttccagtt atgcagcacc tggctaagaa tgtagtcatg gtaaatcaag gacttacaaa     1440

gcacatgact gtcaagaaca agtatgccac atcgaagcat gctaagatca gcactctacc     1500

acagctgaat tctgcactag ttcaagattt agccaaggct gtggcaaagg tgtaacttgt     1560

aaacttgagt tggagtacta tatttacaaa taaaattggc accatgtgcc atctgtacat     1620

attactgttg catttacttt taataaagct tgtggcccct tttacttttt tatagcttaa     1680

ctaatttgaa tgtggttact tcctactgta gggtagcgga aaagttgtct taaaaggtat     1740

ggtggggata tttttaaaaa ctccttttgg tttacctggg gatccaattg atgtatatgt     1800

ttatatactg ggttcttgtt ttatatacct ggcttttact ttattaatat gagttactga     1860

aggtgatgga ggtatttgaa aattttactt ccataggaca tactgcatgt aagccaagtc     1920

atggagaatc tgctgcatag ctctatttta aagtaaaagt ctaccaccga atccctagtc     1980

cccctgtttt ctgtttcttc ttgtgattgc tgccataatt ctaagttatt tacttttacc     2040

actatttaag ttatcaactt tagctagtat cttcaaactt tcactttgaa aaatgagaat     2100

tttatattct aagccagttt tcattttggt tttgtgtttt ggttaataaa acaatactca     2160

aatacaaaaa aaaaaaa                                                    2177


<210>  1658
<211>  6008
<212>  DNA
<213>  homo sapiens

<400>  1658
atcgcctggg taggtttcca gggaaggcag cgagcaggat cccctactct gcgggcggcg       60

cgaggcgtct ggctcttcgc ggcggcggcg aggggaaagg gagcgcgggg gctgggtgga      120

atcgaggagt gaggaaaaag ggaaggggcg ggggagaggg accagggaag gcgtcggggg      180

gaatctcgcg agggttggag ttttggcgag agtttgtgga agatggcgcc tgttgtgaca      240

ggtcattgaa attatgagac tatcattcaa atggaagcat tatagttctt cggaaccatt      300

atgatctcaa aacgaaagga gaatgataca gatacactgg ctgaggtgtt ttgaggtgca      360

tcgaagtgtt ccaagctgtg acttacctta acatgttctt gaagtaccat ggcgtggatt      420

aaaaggaaat ttggtgagcg gcctccacct aaacgactta ctagggaagc tatgcgaaat      480

tatttaaaag agcgagggga tcaaacagta cttattcttc atgcaaaagt tgcacagaag      540

tcatatggaa atgaaaaaag gtttttttgc ccacctcctt gtgtatatct tatgggcagt      600

ggatggaaga aaaaaaaaga acaaatggaa cgcgatggtt gttctgaaca agagtctcaa      660

ccgtgtgcat ttattgggat aggaaatagt gaccaagaaa tgcagcagct aaacttggaa      720

ggaaagaact attgcacagc caaaacattg tatatatctg actcagacaa gcgaaagcac      780

ttcatgttgt ctgtaaagat gttctatggc aacagtgatg acattggtgt gttcctcagc      840

aagcggataa aagtcatctc caaaccttcc aaaaagaagc agtcattgaa aaatgctgac      900

ttatgcattg cctcaggaac aaaggtggct ctgtttaatc gactacgatc ccagacagtt      960

agtaccagat acttgcatgt agaaggaggt aattttcatg ccagttcaca gcagtgggga     1020

gcctttttta ttcatctctt ggatgatgat gaatcagaag gagaagaatt cacagtccga     1080

gatggctaca tccattatgg acaaacagtc aaacttgtgt gctcagttac tggcatggca     1140

ctcccaagat tgataattag gaaagttgat aagcagaccg cattattgga tgcagatgat     1200

cctgtgtcac aactccataa atgtgcattt taccttaagg atacagaaag aatgtatttg     1260

tgcctttctc aagaaagaat aattcaattt caggccactc catgtccaaa agaaccaaat     1320

aaagagatga taaatgatgg cgcttcctgg acaatcatta gcacagataa ggcagagtat     1380

acattttatg agggaatggg ccctgtcctt gccccagtca ctcctgtgcc tgtggtagag     1440

agccttcagt tgaatggcgg tggggacgta gcaatgcttg aacttacagg acagaatttc     1500

actccaaatt tacgagtgtg gtttggggat gtagaagctg aaactatgta caggtgtgga     1560

gagagtatgc tctgtgtcgt cccagacatt tctgcattcc gagaaggttg gagatgggtc     1620

cggcaaccag tccaggttcc agtaactttg gtccgaaatg atggaatcat ttattccacc     1680

agccttacct ttacctacac accagaacca gggccgcggc cacattgcag tgcagcagga     1740

gcaatccttc gagccaattc aagccaggtg ccccctaacg aatcaaacac aaacagcgag     1800

ggaagttaca caaacgccag cacaaattca accagtgtca catcatctac agccacagtg     1860

gtatcctaac taccgtcttt ttgctaggac ttaaactgac ttgagtgtgg caaaaagtta     1920

acaaaaaagg agaaaaaatg aacaatcgtt tgtggtttct tgggaaaact tttcatacca     1980

ggtgatacta ttcaaaaacc ccgttgtctc cctgcaagtg ctgatttgaa atgcagaagc     2040

cacagtaaaa aaaaaaaaaa aaaaaaaaaa aaagaaaaaa aaatcaaaat gtataaatat     2100

tggaaatcaa gtttttcagc tgttttgttg gttggttggt tggtttttgt ttggttttgt     2160

ttaaatgggc aagaagtaaa taatgtggct ggaatacaag ttgaacaaac tagaagacac     2220

aaatctaaca tagtttttat ggaccaagga acttgtatat tgtataagct ttagtaaaag     2280

gtacattttc accatacctt tttttatatc acggtattat agtacacctt gttaccaaat     2340

aggttgttct cttccccacc cacctttgag cttttgctct aaaatacatt caggttccaa     2400

gcctgaccat ccttgtttaa tctatcatac tcttccaggt tttttttttt tggtctaagg     2460

ctggaacttt tttctttttt ttcagctgaa gtcttatgac ttttcatgag tcaaaattgt     2520

ttggatttca gcaagtcaaa tcttgcaaag gcctgcatat tttttttaag attatatgaa     2580

gtctgtgcaa aagctttaaa aaaatgcctc tgccttgcct gcaatacatg caatgtatgt     2640

taacttagtc tctcttctca gacactgttg gtagttattt ctgtgttttc ctttttttaa     2700

aaaaaaatat ggacttattg tggttatctg agaggttcta acattcacat gcaatttggt     2760

gtggccattt agctattaat gagttaatgg cgcagaactt gttgatattt gaagtgttct     2820

ctcccctttt cccatgacgt aaatacatag gtgtgttcca ggatttgttc aggtttttcc     2880

cccctcctaa tcttgtacat aacttgtatt atgtgtaagt taaacatttt attttgaact     2940

tggaatgttc ccagtgattt cattcagcag ggtattttct gccttgttgg caagtgacaa     3000

aaaatatggg aagtatttgc taccagttgg tagatggtgc ccttaatggt agaatgagga     3060

aaatgtccgc aaaagcatgt tttattatct ttactttttt ggggggttgg agggggtagc     3120

ctagccagaa catcattgta atcttaaaac ataagatgct tttattagat gatcaactaa     3180

aatagctgga agacagtact ttagaaacag atagttgtaa gattataaaa tgcaaatgta     3240

acttatgttt tcattttttt ctctgccttt tttgtttgtt tgttttctct tttccagtac     3300

tgagcatctc cacaaatgtc tcctaactca gaaaatgttt cttttctttt cagttgagat     3360

ttggttgcat tcagggttgt aggttggcct tgcttgctaa ccccgccggt tttaccgtgc     3420

tttcattcct gaactttgtt tatgcctttg tttggtttct tcgaaattgc agcagactca     3480

ttgggctaca tttagtacag gaaccacgtg tgtaatgtta tacaacacag tctagtaata     3540

caatcatccc tcttagagta aaaactacct ctagattgtg gtaagctttt actgtcccat     3600

aaaacaggag ccacagtacc ttatgaatgc aaaactgtaa cttcctacag tgtttcccta     3660

cagaacattg tctttctggt gtcctgggct gttttgaaaa agtttccatt aatagacttt     3720

ttagaaatta ttattagtag catttttttt ccagctttgc tgtcttcatc actcactcta     3780

tgctcagact atgccactgt aaatattctt cctaacatct ttaaatcgcc ttttcctcag     3840

ttttcaaggg gaaggtcatt tgtaaagcac gttaggtggt taaatcagtt attgcggttt     3900

tctcttactg caagcctttt taatcacccc caggctgcat tttattctat atcgcctttt     3960

ttcttcaaat ctgctccaat cactcacttc tctcttataa gctaatcctg cctcacacct     4020

taaatctgtt tcagtgatca agggcagaac tcattgtggc cttatctttc tttgttgtaa     4080

ttgttcactg tctctttctt acagaccact tatttctgag tagtagttat tcctctctat     4140

ggagtcatgg caggaatcat tacacagtgc ttttgttcag agcatggaca tgttcctagt     4200

gctgctttgc tttaacggcc acaagtttcc tccacttcct aggtttggta tttagttaag     4260

gaatcatatt aaattaacca ataacaaaag agatactttt gaagaacaaa ctattcctta     4320

cccatttttg tagctcaaaa ataatttttc aagttcatga ccttattaaa atgaacttgt     4380

gtttttttaa caaacatgta tgttttattt tgatagtttc tttccgtaag ataattgaaa     4440

tattatactg taaacccttt tcttttcttt ttttgaaaag tccaagaatg tacttataca     4500

ggcatttttc cccacctatt tttggccatt ctcataccac agactaaaga gtgaaatgat     4560

ttgtccattg tagcttattg tttatcagta gttcttttgt cagctgctta cattttttct     4620

ttcatggttt tgtgaatcat tttcagtatg taatttatag gaaccttgtc ctctggttat     4680

agtagactgt gtgccctcct ccagtgatgg cattattaga catgctggtc atttaccctc     4740

agaaagactc tcttattaga atggtgagtg cttcagttat agtatgtttg aatttttaaa     4800

aaattctgtt ttagaaatgt atcttatgct ctcatgacta tgcagtttct aaacatacac     4860

atagaagctg agtctctgat ccaatatgtt tttatttgtt ccatttaatt tatcacatag     4920

attgggaagg caagctaaaa gccttaaaaa tgccctttat attttgagtg atttcagcgt     4980

tgaacactag tatactatct aaatttgctg ctcactttct ttaaactgtg gcaattaaag     5040

gcatgtttat acatgactta atcgtgaaat gtttgtcact cttactgcac agacttatct     5100

gcaatcataa ctggttagtt tttttgtttt gttttgtttt attgttttta atgaaactgg     5160

taccatctgt gctttcacaa aaaacttcca atgccatttt tgagaactaa cctaactagt     5220

catgctaacc agaaaatcca ctggggagga ggttcctttt gaaacaaaat gctgttcagt     5280

tagtaaccaa gttactttga ttgcaaaagc agctgtgttt ctgataagta ctgaacaaat     5340

gtgtgtaatt ttctgtgcca gacttatgac tttgttttca agcactgtaa tgtgggatgg     5400

atggttagaa acaataatat attagggttt ctgtttaacc ctttcaggac tgaactgtat     5460

ctccttttgt taattttccc ctgtgttgtg ataaatgttt gccagcattc agtactgtgt     5520

tggtccagat gtaggtttat atgctcattt ttagcttatt tcttgtacct tgcagcatgc     5580

tctacgcatt cagtccttaa ggggtttatt ttacaaactg tgcgcctgta aggtttatta     5640

gcaataagat agaaaattga gcaagtttat accataattt tgtagaaaaa aagaatctgc     5700

tcagttccat atttcatccg tgaaaaactt gcaatacgag cagtttcaag gaataaataa     5760

aaaggaaatg taaaccattg taaaagtctt ctgtcgaatg tgcctgatgc atgtattatc     5820

gtcttttatt tcagaatact tcataaagat aaaattaaat tctatattat agttggtgta     5880

tttacaatct taccatgtac atcacatcaa agtgatagct ctactaattt aatttccttg     5940

tcaatgtttt taactatata gtgctttaaa gagatttttt ttccctgtgt aaaaaaaaaa     6000

aaaaaaaa                                                              6008


<210>  1659
<211>  4191
<212>  DNA
<213>  homo sapiens

<400>  1659
tgacccaccg gccttgagga aagcgcaaac gtaaaaaaag attgaaaccg gagaggcgaa       60

tgcatctgtt tacgctagga ccacgctcga cgtcggagaa aagcccacac actcacagtt      120

tccagacctg gctgcttgcc gaaactcaga ttctcggcac ctccagcagc tggcttcgcc      180

aacggcgttg aacaagggtc gcagctcaat gacgtcatat ctccctacct acctccaggg      240

ttccgcctca cgctctatgt cgcgcgcgcg cactacgtcc tatggcttgc gcgtgcggcg      300

gctgggcacc gccattttgg ccggtggccg tgagaacacg ctgtgtggct gaaaagtgaa      360

ggcaagagct gatttggcct ctgtgctccc ctccgcaagg ggatcgtttt ctccagagct      420

ggatattctt tcgcccagtt atggcagaca agttaacgag aattgctatt gtcaaccatg      480

acaaatgtaa acctaagaaa tgtcgacagg aatgcaaaaa gagttgtcct gtagttcgaa      540

tgggaaaatt atgcatagag gttacacccc agagcaaaat agcatggatt tccgaaactc      600

tttgtattgg ttgtggtatc tgtattaaga aatgcccctt tggcgcctta tcaattgtca      660

atctaccaag caacttggaa aaagaaacca cacatcgata ttgtgccaat gccttcaaac      720

ttcacaggtt gcctatccct cgtccaggtg aagttttggg attagttgga actaatggta      780

ttggaaagtc aactgcttta aaaattttag caggaaaaca aaagccaaac cttggaaagt      840

acgatgatcc tcctgactgg caggagattt tgacttattt ccgtggatct gaattacaaa      900

attactttac aaagattcta gaagatgacc taaaagccat catcaaacct caatatgtag      960

accagattcc taaggctgca aaggggacag tgggatctat tttggaccga aaagatgaaa     1020

caaagacaca ggcaattgta tgtcagcagc ttgatttaac ccacctaaaa gaacgaaatg     1080

ttgaagatct ttcaggagga gagttgcaga gatttgcttg tgctgtcgtt tgcatacaga     1140

aagctgatat tttcatgttt gatgagcctt ctagttacct agatgtcaag cagcgtttaa     1200

aggctgctat tactatacga tctctaataa atccagatag atatatcatt gtggtggaac     1260

atgatctaag tgtattagac tatctctccg acttcatctg ctgtttatat ggtgtaccaa     1320

gcgcctatgg agttgtcact atgcctttta gtgtaagaga aggcataaac atttttttgg     1380

atggctatgt tccaacagaa aacttgagat tcagagatgc atcacttgtt tttaaagtgg     1440

ctgagacagc aaatgaagaa gaagttaaaa agatgtgtat gtataaatat ccaggaatga     1500

agaaaaaaat gggagaattt gagctagcaa ttgtagctgg agagtttaca gattctgaaa     1560

ttatggtgat gctgggggaa aatggaacgg gtaaaacgac atttatcaga atgcttgctg     1620

gaagacttaa acctgatgaa ggaggagaag taccagttct aaatgtcagt tataagccac     1680

agaaaattag tcccaaatca actggaagtg ttcgccagtt actacatgaa aagataagag     1740

atgcttatac tcacccacaa tttgtgaccg atgtaatgaa gcctctgcaa attgaaaaca     1800

tcattgatca agaggtgcag acattatctg gtggtgaact acagcgagta gctttagccc     1860

tttgcttggg caaacctgct gatgtctatt taattgatga accatctgca tatttggatt     1920

ctgagcaaag actgatggca gctcgagttg tcaaacgttt catactccat gcaaaaaaga     1980

cagcctttgt tgtggaacat gacttcatca tggccaccta tctagcggat cgcgtcatcg     2040

tttttgatgg tgttccatct aagaacacag ttgcaaacag tcctcaaacc cttttggctg     2100

gcatgaataa atttttgtct cagcttgaaa ttacattcag aagagatcca aacaactata     2160

ggccacgaat aaacaaactt aattcaatta aggatgtaga acaaaagaag agtggaaact     2220

actttttctt ggatgattag actgactctg agaatattga taagccattt attaaaagga     2280

gtatttacta gaattttttg tcatataaaa cttgaatcag gattttatgc cccacatact     2340

ctggaacttg aagtataata tacttaatat aacataaaaa gccagttggg ttctaaattg     2400

tagttgaaac acagaaaatg ccacttttct gttcctgaag aggctctttt gtgcataata     2460

ttctaaaatg aagacatttc aagctataca aattacttcc aagttttcat gatgtatggg     2520

aagattttca gtaggtgtat tatattcacg gtaccaaatg ctgaccagtg ttgctccatt     2580

ttttaaatct tgaaaagggt ttctgtactt acctggtttg ccaagtatgc cagtgtaatg     2640

aaactgccct tattttaaaa gccagtcaaa gattccactg attgacattt gataaataaa     2700

catcaggatt atgtttattg tttgttttca gtctttgcac tatattacca gtatatggtt     2760

tccgaggaag attatctact gcaaaacacc actgttggaa aaataggtat ttttaaattg     2820

tttttaatct tttttggtgc ttttaaacat gtttagcaaa aaccaattca gttccattcc     2880

ccgcaaaaaa cccctaactt tactctgaac tttttttgtt tttgcattcc atgaggttct     2940

gtattcagtc attctctagg taatgtcatt tttgtacaca tatatttata taatcactga     3000

ttgagattta ggaaaaagca tttctaaaga atatttgctt cccttagaac tacagactcg     3060

aaatctttaa agatggtgcc taagcatcta tgtatttttt ttaagttcca cagatttttc     3120

tgttgggcag ccaaggatta taaaccactt ccctaaaggc aacattaatg caaaagtccc     3180

cagatggcaa tacaaagtat cccctggtac cacatatatt catttgtgag tttggatata     3240

gagcacatta tctaaaccat tttgtagttc caaaaaccca tctaaatttc ttgagttcct     3300

gaattttgaa caggattacc tggagcctgg agccacttta agttgtactt ctgactaaac     3360

tggaattatg agtgaggaag agtgtttact aaataaatga ctggggcaag caaaattgag     3420

gaggaaatta gaaactgttt gacaaacttt aagagctact tgaaataaca gaagtcttga     3480

ttaatatgca aataatggct agaaagtatg gtttaactgg accctattat gccttttaaa     3540

aataatttca gtaacccata aatacatgtt gtaaaaaatt caaatataca gaatggaata     3600

aaaaaatgat ctccctttat taccctccca aaggttacca gcgtttgaat ttaataatgt     3660

atattctttc atgctttttt ctgtgcactt acctaagtgt gaatatgtaa agggtttgtt     3720

ttgtatacaa atgggattat actaaaataa gtaatgccta tttttaagga taggttaaat     3780

ttgtgaatga tcatttcaaa tatattgaat aaaataagca aaagctattg ttatttactg     3840

atcctggatt gtcttaaaga aagtacttgt gatataagag cacagttcta cttactgcta     3900

atgacagaat atgtattaaa cgtattttca tgtaaatgaa atctttaaaa tatgtatctt     3960

aaaattttac atagcaacag aaaggcctac aattgctaac acaagaaaaa tacttataaa     4020

atcagtataa aatcaatgca gatgttagca aaagaatgag actacttcat atgtcctaat     4080

tggaaaaagt ctcaaatact taaaaaaaca aaaaactgga acagtttatt atactaccat     4140

ttttgtgaaa atatacaaaa tattgaaata aaggaatact caagaaacag a              4191


<210>  1660
<211>  3871
<212>  DNA
<213>  homo sapiens

<400>  1660
catttcccat aagcccgcgg ggcagggcga ggggcgggcg tcggggacat taccggacag       60

gccttgtccg gcaataccaa gtttcatgca ggctcttggg aaagctggtg ctgctgctgc      120

ctgattcccg ccgacagacc ttgggaccgg ggccaacact ggcagctgga gatggcggac      180

acgagatccg tgcacgagac taggtttgag gcggccgtga aggtgatcca gagtttgccg      240

aagaatggtt cattccagcc aacaaatgaa atgatgctta aattttatag cttctataag      300

caggcaactg aaggaccctg taaactttca aggcctggat tttgggatcc tattggaaga      360

tataaatggg atgcttggag ttcactgggt gatatgacca aagaggaagc catgattgca      420

tatgttgaag aaatgaaaaa gattattgaa actatgccaa tgactgagaa agttgaagaa      480

ttgctgcgtg tcataggtcc attttatgaa attgtcgagg acaaaaagag tggcaggagt      540

tctgatataa cctcagatct tggtaatgtt ctcacttcta ctccaaacgc caaaaccgtt      600

aatggtaaag ctgaaagcag tgacagtgga gccgagtctg aggaagaaga ggcccaagaa      660

gaagtgaaag gagcagaaca aagtgataat gataagaaaa tgatgaagaa gtcagcagac      720

cataagaatt tggaagtcat tgtcactaat ggctatgata aagatggctt tgttcaggat      780

atacagaatg acattcatgc cagttcttcc ctgaatggca gaagcactga agaagtaaag      840

cccattgatg aaaacttggg gcaaactgga aaatctgctg tttgcattca ccaagatata      900

aatgatgatc atgttgaaga tgttacagga attcagcatt tgacaagcga ttcagacagt      960

gaagtttact gtgattctat ggaacaattt ggacaagaag agtctttaga cagctttacg     1020

tccaacaatg gaccatttca gtattacttg ggtggtcatt ccagtcaacc catggaaaat     1080

tctggatttc gtgaagatat tcaagtacct cctggaaatg gcaacattgg gaatatgcag     1140

gtggttgcag ttgaaggaaa aggtgaagtc aagcatggag gagaagatgg caggaataac     1200

agcggagcac cacaccggga gaagcgaggc ggagaaactg acgaattctc taatgttaga     1260

agaggaagag gacataggat gcaacacttg agcgaaggaa ccaagggccg gcaggtggga     1320

agtggaggtg atggggagcg ctggggctcc gacagagggt cccgaggcag cctcaatgag     1380

cagatcgccc tcgtgctgat gagactgcag gaggacatgc agaatgtcct tcagagactg     1440

cagaaactgg aaacgctgac tgctttgcag gcaaaatcat caacatcaac attgcagact     1500

gctcctcagc ccacctcaca gagaccatct tggtggccct tcgagatgtc tcctggtgtg     1560

ctaacgtttg ccatcatatg gccttttatt gcacagtggt tggtgtattt atactatcaa     1620

agaaggagaa gaaaactgaa ctgaggaaaa tggtgttttc ctcaagaaga ctactggaac     1680

tggatgacct cagaatgaac tggattgtgg tgttcacaag aaaatcttag tttgtgatga     1740

ttacattgct ttttgttgtc cagtagttta gtttgtgtac atatatacac atatatattt     1800

tgcactacac aaacgataac attttaagga ctaatattgc tgatacttga ataatcaatc     1860

tctactaggt tataagtagt atacacagat ttaccctgcc cttgaacttg aaggacatta     1920

aattattaat gatcatttgg taacatgttt acctgattat cttccataga gtaacataag     1980

ctgcttttca aaggtaccat tgtgataatg agatcaaatt tataagttat tatttttaat     2040

tttctaaatt aaataaaaga aagaatgcaa accaggagtg aatttcaaat gagatgtaat     2100

cgactttata tcttagtcac ggagttgcca tggcatgtag tagaaaacca caggaagaat     2160

ggtcatattc actttgtggg ctgcccataa tctttcttgg gcattcacaa ctcttgagtt     2220

tggtgttcag gcatcattat taaaaagtgg agtcctatgt accagactga gtttttacaa     2280

atgatttgca ggctagacat aacccactga tggaaatggt gaagaatgag cttcatgtag     2340

gtttaaaagt gtattctgag cctgtagatg attaatcagg tttttattca atcatataaa     2400

tgtattcctt tgtaatcatt tttgtttaac tgaggatatc tagtgtctgc ttcatagggt     2460

gctttgaaat ataaaatgaa aacttattta tactgttttt acaacagtca aaaaggaaac     2520

acacgaaaat cacttttctg caactgatga actatataga ctggactctt aacctcttag     2580

tgcctcagtt tttccttcgg ggtatactat tttagataca cctacttcac aggagtactg     2640

gagggatttg caagctaacg ggccaaatgc ttccatagga ataaggcatg cccagctaac     2700

agaaatttaa gtccctcttc cccacctctc tcatctagac caaaaagaag actacaattt     2760

agatccttgg agacttttcc tgtatgcctt ccaaaacttc ctgctcactt agatgtacct     2820

tgtgctttga agatttcttt gatgcagtct ttgtaacaaa taattttttt ttttaaatgg     2880

agtttctctc ttgttgccca ggctggaggg caatggcgtg atcttggctc actgcaactt     2940

ccacctcctg ggttcaagtg attctcctgc ctcactccca agtagctggg attacaggca     3000

tgcaccacca tgcctggcta attttgtatt tttagtagag acggggtttc tccatgttgg     3060

taaggctgat ctcaaactcc caacctcagg tgatctgcct gcctcggcct cccaaagtgc     3120

tgggattaga ggcgtgagcc actgcacctg gcctgtagca aataattttt aagcattctc     3180

aagatgtatg atgttgggtt taacatcata tgttcacagt gttttaaata agaaataatc     3240

tgtctttagt atacaggatg gttctttgtt tgcctgaaaa gtataagaat acaatttact     3300

tttcccaaac tctttttcct tatttttttc tttcaaataa ctttaattat ttaatcccat     3360

actgattaaa atatgtctgt ctaaagggat ctactactat ttgcttttaa aaaagtgttc     3420

cctatttatt taggaaaaag tgaagcaagc aactgaattt atatgtaaaa ataacattta     3480

gacctgtgga tcaaagatta ttttcaaaaa tgagatatca atttggtatc agtaaaaagt     3540

gtcttttctc ttagtatata aataaataaa atgcaaatta agagtgtaag cagttgtgaa     3600

tcattacaag cagtctggga taactaactc ctagggataa ccatttctat cctgttccaa     3660

agtcttattt tatagtttga aaagcacttt gcacacagtt cttgtatata aaagtaaaga     3720

tgtaattata ggatatagtg ttcctgcttt gtttaataag aacctcattt aaacttgaca     3780

gctatggtat ttttttaatg ataacttctt ttctgtttat tgtaaaacta agttaaaaat     3840

aaaaggttaa tgagaaatga aaaaaaaaaa a                                    3871


<210>  1661
<211>  3996
<212>  DNA
<213>  homo sapiens

<400>  1661
tgcactgctg ctgcggcggc ggcggcgcca gtgggtcctc cggtgactct ggggcggggc       60

tgtggggagg gcacggactg acagacggac tccggcggaa tggggggtgt ggctgctccg      120

ccagggtccc cagggtggga gagcggctcc gcggccaccg atgcccggac cccctctgtc      180

ttctgctaga catgctcttc ctctcgtttc atgcaggctc ttgggaaagc tggtgctgct      240

gctgcctgat tcccgccgac agaccttggg accggggcca acactggcag ctggagatgg      300

cggacacgag atccgtgcac gagactaggt ttgaggcggc cgtgaaggtg atccagagtt      360

tgccgaagaa tggttcattc cagccaacaa atgaaatgat gcttaaattt tatagcttct      420

ataagcaggc aactgaagga ccctgtaaac tttcaaggcc tggattttgg gatcctattg      480

gaagatataa atgggatgct tggagttcac tgggtgatat gaccaaagag gaagccatga      540

ttgcatatgt tgaagaaatg aaaaagatta ttgaaactat gccaatgact gagaaagttg      600

aagaattgct gcgtgtcata ggtccatttt atgaaattgt cgaggacaaa aagagtggca      660

ggagttctga tataacctca gatcttggta atgttctcac ttctactcca aacgccaaaa      720

ccgttaatgg taaagctgaa agcagtgaca gtggagccga gtctgaggaa gaagaggccc      780

aagaagaagt gaaaggagca gaacaaagtg ataatgataa gaaaatgatg aagaagtcag      840

cagaccataa gaatttggaa gtcattgtca ctaatggcta tgataaagat ggctttgttc      900

aggatataca gaatgacatt catgccagtt cttccctgaa tggcagaagc actgaagaag      960

taaagcccat tgatgaaaac ttggggcaaa ctggaaaatc tgctgtttgc attcaccaag     1020

atataaatga tgatcatgtt gaagatgtta caggaattca gcatttgaca agcgattcag     1080

acagtgaagt ttactgtgat tctatggaac aatttggaca agaagagtct ttagacagct     1140

ttacgtccaa caatggacca tttcagtatt acttgggtgg tcattccagt caacccatgg     1200

aaaattctgg atttcgtgaa gatattcaag tacctcctgg aaatggcaac attgggaata     1260

tgcaggtggt tgcagttgaa ggaaaaggtg aagtcaagca tggaggagaa gatggcagga     1320

ataacagcgg agcaccacac cgggagaagc gaggcggaga aactgacgaa ttctctaatg     1380

ttagaagagg aagaggacat aggatgcaac acttgagcga aggaaccaag ggccggcagg     1440

tgggaagtgg aggtgatggg gagcgctggg gctccgacag agggtcccga ggcagcctca     1500

atgagcagat cgccctcgtg ctgatgagac tgcaggagga catgcagaat gtccttcaga     1560

gactgcagaa actggaaacg ctgactgctt tgcaggcaaa atcatcaaca tcaacattgc     1620

agactgctcc tcagcccacc tcacagagac catcttggtg gcccttcgag atgtctcctg     1680

gtgtgctaac gtttgccatc atatggcctt ttattgcaca gtggttggtg tatttatact     1740

atcaaagaag gagaagaaaa ctgaactgag gaaaatggtg ttttcctcaa gaagactact     1800

ggaactggat gacctcagaa tgaactggat tgtggtgttc acaagaaaat cttagtttgt     1860

gatgattaca ttgctttttg ttgtccagta gtttagtttg tgtacatata tacacatata     1920

tattttgcac tacacaaacg ataacatttt aaggactaat attgctgata cttgaataat     1980

caatctctac taggttataa gtagtataca cagatttacc ctgcccttga acttgaagga     2040

cattaaatta ttaatgatca tttggtaaca tgtttacctg attatcttcc atagagtaac     2100

ataagctgct tttcaaaggt accattgtga taatgagatc aaatttataa gttattattt     2160

ttaattttct aaattaaata aaagaaagaa tgcaaaccag gagtgaattt caaatgagat     2220

gtaatcgact ttatatctta gtcacggagt tgccatggca tgtagtagaa aaccacagga     2280

agaatggtca tattcacttt gtgggctgcc cataatcttt cttgggcatt cacaactctt     2340

gagtttggtg ttcaggcatc attattaaaa agtggagtcc tatgtaccag actgagtttt     2400

tacaaatgat ttgcaggcta gacataaccc actgatggaa atggtgaaga atgagcttca     2460

tgtaggttta aaagtgtatt ctgagcctgt agatgattaa tcaggttttt attcaatcat     2520

ataaatgtat tcctttgtaa tcatttttgt ttaactgagg atatctagtg tctgcttcat     2580

agggtgcttt gaaatataaa atgaaaactt atttatactg tttttacaac agtcaaaaag     2640

gaaacacacg aaaatcactt ttctgcaact gatgaactat atagactgga ctcttaacct     2700

cttagtgcct cagtttttcc ttcggggtat actattttag atacacctac ttcacaggag     2760

tactggaggg atttgcaagc taacgggcca aatgcttcca taggaataag gcatgcccag     2820

ctaacagaaa tttaagtccc tcttccccac ctctctcatc tagaccaaaa agaagactac     2880

aatttagatc cttggagact tttcctgtat gccttccaaa acttcctgct cacttagatg     2940

taccttgtgc tttgaagatt tctttgatgc agtctttgta acaaataatt ttttttttta     3000

aatggagttt ctctcttgtt gcccaggctg gagggcaatg gcgtgatctt ggctcactgc     3060

aacttccacc tcctgggttc aagtgattct cctgcctcac tcccaagtag ctgggattac     3120

aggcatgcac caccatgcct ggctaatttt gtatttttag tagagacggg gtttctccat     3180

gttggtaagg ctgatctcaa actcccaacc tcaggtgatc tgcctgcctc ggcctcccaa     3240

agtgctggga ttagaggcgt gagccactgc acctggcctg tagcaaataa tttttaagca     3300

ttctcaagat gtatgatgtt gggtttaaca tcatatgttc acagtgtttt aaataagaaa     3360

taatctgtct ttagtataca ggatggttct ttgtttgcct gaaaagtata agaatacaat     3420

ttacttttcc caaactcttt ttccttattt ttttctttca aataacttta attatttaat     3480

cccatactga ttaaaatatg tctgtctaaa gggatctact actatttgct tttaaaaaag     3540

tgttccctat ttatttagga aaaagtgaag caagcaactg aatttatatg taaaaataac     3600

atttagacct gtggatcaaa gattattttc aaaaatgaga tatcaatttg gtatcagtaa     3660

aaagtgtctt ttctcttagt atataaataa ataaaatgca aattaagagt gtaagcagtt     3720

gtgaatcatt acaagcagtc tgggataact aactcctagg gataaccatt tctatcctgt     3780

tccaaagtct tattttatag tttgaaaagc actttgcaca cagttcttgt atataaaagt     3840

aaagatgtaa ttataggata tagtgttcct gctttgttta ataagaacct catttaaact     3900

tgacagctat ggtatttttt taatgataac ttcttttctg tttattgtaa aactaagtta     3960

aaaataaaag gttaatgaga aatgaaaaaa aaaaaa                               3996


<210>  1662
<211>  3996
<212>  DNA
<213>  homo sapiens

<400>  1662
tgcactgctg ctgcggcggc ggcggcgcca gtgggtcctc cggtgactct ggggcggggc       60

tgtggggagg gcacggactg acagacggac tccggcggaa tggggggtgt ggctgctccg      120

ccagggtccc cagggtggga gagcggctcc gcggccaccg atgcccggac cccctctgtc      180

ttctgctaga catgctcttc ctctcgtttc atgcaggctc ttgggaaagc tggtgctgct      240

gctgcctgat tcccgccgac agaccttggg accggggcca acactggcag ctggagatgg      300

cggacacgag atccgtgcac gagactaggt ttgaggcggc cgtgaaggtg atccagagtt      360

tgccgaagaa tggttcattc cagccaacaa atgaaatgat gcttaaattt tatagcttct      420

ataagcaggc aactgaagga ccctgtaaac tttcaaggcc tggattttgg gatcctattg      480

gaagatataa atgggatgct tggagttcac tgggtgatat gaccaaagag gaagccatga      540

ttgcatatgt tgaagaaatg aaaaagatta ttgaaactat gccaatgact gagaaagttg      600

aagaattgct gcgtgtcata ggtccatttt atgaaattgt cgaggacaaa aagagtggca      660

ggagttctga tataacctca gatcttggta atgttctcac ttctactcca aacgccaaaa      720

ccgttaatgg taaagctgaa agcagtgaca gtggagccga gtctgaggaa gaagaggccc      780

aagaagaagt gaaaggagca gaacaaagtg ataatgataa gaaaatgatg aagaagtcag      840

cagaccataa gaatttggaa gtcattgtca ctaatggcta tgataaagat ggctttgttc      900

aggatataca gaatgacatt catgccagtt cttccctgaa tggcagaagc actgaagaag      960

taaagcccat tgatgaaaac ttggggcaaa ctggaaaatc tgctgtttgc attcaccaag     1020

atataaatga tgatcatgtt gaagatgtta caggaattca gcatttgaca agcgattcag     1080

acagtgaagt ttactgtgat tctatggaac aatttggaca agaagagtct ttagacagct     1140

ttacgtccaa caatggacca tttcagtatt acttgggtgg tcattccagt caacccatgg     1200

aaaattctgg atttcgtgaa gatattcaag tacctcctgg aaatggcaac attgggaata     1260

tgcaggtggt tgcagttgaa ggaaaaggtg aagtcaagca tggaggagaa gatggcagga     1320

ataacagcgg agcaccacac cgggagaagc gaggcggaga aactgacgaa ttctctaatg     1380

ttagaagagg aagaggacat aggatgcaac acttgagcga aggaaccaag ggccggcagg     1440

tgggaagtgg aggtgatggg gagcgctggg gctccgacag agggtcccga ggcagcctca     1500

atgagcagat cgccctcgtg ctgatgagac tgcaggagga catgcagaat gtccttcaga     1560

gactgcagaa actggaaacg ctgactgctt tgcaggcaaa atcatcaaca tcaacattgc     1620

agactgctcc tcagcccacc tcacagagac catcttggtg gcccttcgag atgtctcctg     1680

gtgtgctaac gtttgccatc atatggcctt ttattgcaca gtggttggtg tatttatact     1740

atcaaagaag gagaagaaaa ctgaactgag gaaaatggtg ttttcctcaa gaagactact     1800

ggaactggat gacctcagaa tgaactggat tgtggtgttc acaagaaaat cttagtttgt     1860

gatgattaca ttgctttttg ttgtccagta gtttagtttg tgtacatata tacacatata     1920

tattttgcac tacacaaacg ataacatttt aaggactaat attgctgata cttgaataat     1980

caatctctac taggttataa gtagtataca cagatttacc ctgcccttga acttgaagga     2040

cattaaatta ttaatgatca tttggtaaca tgtttacctg attatcttcc atagagtaac     2100

ataagctgct tttcaaaggt accattgtga taatgagatc aaatttataa gttattattt     2160

ttaattttct aaattaaata aaagaaagaa tgcaaaccag gagtgaattt caaatgagat     2220

gtaatcgact ttatatctta gtcacggagt tgccatggca tgtagtagaa aaccacagga     2280

agaatggtca tattcacttt gtgggctgcc cataatcttt cttgggcatt cacaactctt     2340

gagtttggtg ttcaggcatc attattaaaa agtggagtcc tatgtaccag actgagtttt     2400

tacaaatgat ttgcaggcta gacataaccc actgatggaa atggtgaaga atgagcttca     2460

tgtaggttta aaagtgtatt ctgagcctgt agatgattaa tcaggttttt attcaatcat     2520

ataaatgtat tcctttgtaa tcatttttgt ttaactgagg atatctagtg tctgcttcat     2580

agggtgcttt gaaatataaa atgaaaactt atttatactg tttttacaac agtcaaaaag     2640

gaaacacacg aaaatcactt ttctgcaact gatgaactat atagactgga ctcttaacct     2700

cttagtgcct cagtttttcc ttcggggtat actattttag atacacctac ttcacaggag     2760

tactggaggg atttgcaagc taacgggcca aatgcttcca taggaataag gcatgcccag     2820

ctaacagaaa tttaagtccc tcttccccac ctctctcatc tagaccaaaa agaagactac     2880

aatttagatc cttggagact tttcctgtat gccttccaaa acttcctgct cacttagatg     2940

taccttgtgc tttgaagatt tctttgatgc agtctttgta acaaataatt ttttttttta     3000

aatggagttt ctctcttgtt gcccaggctg gagggcaatg gcgtgatctt ggctcactgc     3060

aacttccacc tcctgggttc aagtgattct cctgcctcac tcccaagtag ctgggattac     3120

aggcatgcac caccatgcct ggctaatttt gtatttttag tagagacggg gtttctccat     3180

gttggtaagg ctgatctcaa actcccaacc tcaggtgatc tgcctgcctc ggcctcccaa     3240

agtgctggga ttagaggcgt gagccactgc acctggcctg tagcaaataa tttttaagca     3300

ttctcaagat gtatgatgtt gggtttaaca tcatatgttc acagtgtttt aaataagaaa     3360

taatctgtct ttagtataca ggatggttct ttgtttgcct gaaaagtata agaatacaat     3420

ttacttttcc caaactcttt ttccttattt ttttctttca aataacttta attatttaat     3480

cccatactga ttaaaatatg tctgtctaaa gggatctact actatttgct tttaaaaaag     3540

tgttccctat ttatttagga aaaagtgaag caagcaactg aatttatatg taaaaataac     3600

atttagacct gtggatcaaa gattattttc aaaaatgaga tatcaatttg gtatcagtaa     3660

aaagtgtctt ttctcttagt atataaataa ataaaatgca aattaagagt gtaagcagtt     3720

gtgaatcatt acaagcagtc tgggataact aactcctagg gataaccatt tctatcctgt     3780

tccaaagtct tattttatag tttgaaaagc actttgcaca cagttcttgt atataaaagt     3840

aaagatgtaa ttataggata tagtgttcct gctttgttta ataagaacct catttaaact     3900

tgacagctat ggtatttttt taatgataac ttcttttctg tttattgtaa aactaagtta     3960

aaaataaaag gttaatgaga aatgaaaaaa aaaaaa                               3996


<210>  1663
<211>  3374
<212>  DNA
<213>  homo sapiens

<400>  1663
agagcttgca tcacatccgc cgcctgggcg cccaattccg gaaggtgctg cacagctgtg       60

gcggcgggta ctgcgttagt gattagagtt tcttccctgc cggaggtggg atacacggta      120

gcatcatggt cgaggaggta cagaaacatt ctgtacacac ccttgtgttc aggtcgttga      180

agaggaccca tgacatgttt gtagctgata atggaaaacc tgtgccttta gatgaagaga      240

gtcacaaacg aaaaatggca atcaagcttc gtaatgagta tggtcctgtg ttgcatatgc      300

ctacttcaaa agaaaatctt aaagagaagg gtcctcagaa tgcaacggat tcatatgttc      360

ataaacagta ccctgccaat caaggacaag aagttgaata ctttgtggca ggtacacatc      420

catacccacc aggacctggg gttgctttga cagcagatac taagatccag agaatgccaa      480

gtgaatcagc tgcacagtcc ttagcggtgg cattaccttt gcagaccaag gctgatgcaa      540

atcgtactgc ccctagtgga agtgaatacc gacatcctgg ggcttctgac cgtccacagc      600

ctacagcgat gaattcaatt gtcatggaga ctggcaatac caagaactct gcactgatgg      660

ctaaaaaagc ccctacaatg ccaaaacccc agtggcaccc accgtggaaa ctctacaggg      720

ttatcagtgg gcatcttggc tgggttcgat gtattgctgt ggaacctgga aatcagtggt      780

ttgttactgg atctgctgac agaactataa agatctggga cttggctagt ggcaaattaa      840

aactgtcatt gactgggcat attagtactg tgcggggcgt gatagtaagc acaaggagcc      900

catatctgtt ctcttgtgga gaagacaaac aagtgaaatg ctgggatctc gaatacaata      960

aggttatacg gcattatcat ggacatttaa gtgcagtgta tggtttggat ttgcacccga     1020

caatcgatgt gttggtaacc tgtagtcgag attcaactgc acggatttgg gatgtgagaa     1080

ctaaagccag tgtacacaca ttatctggac atacaaatgc agttgctaca gtgagatgtc     1140

aggctgcaga accacaaatt attacaggaa gccatgatac tacaattcga ttatgggatc     1200

tggtggctgg aaaaacaaga gtgacattaa caaatcacaa aaaatcagtt agggctgtgg     1260

ttttacatcc aagacattac acatttgcat ctggttctcc agataacata aagcagtgga     1320

aattccctga tggaagtttc attcaaaatc tttccggtca taatgctatt attaacacat     1380

tgacggtaaa ttctgatgga gtgcttgtat ctggagctga caatggcacc atgcatcttt     1440

gggactggag aactggctac aattttcaga gagttcacgc agctgtgcaa cctgggtctt     1500

tggacagtga atcaggaata tttgcttgtg cttttgatca gtctgaaagt cgattactaa     1560

cagctgaagc tgataaaacc attaaagtat acagagagga tgacacagcc acagaagaaa     1620

ctcatccagt cagctggaaa ccagaaatta tcaagagaaa gagattttaa tgaatgtgga     1680

attttttctc tctctttttt tttcttttta attaaaaaaa aaaaagcttg gcgttcatga     1740

ggatatccag tcattttgtg ctctggctgg gaatataaag gagaaattca cttgcttcaa     1800

tcattgctgc ttcatatttt acaataaact gtcccctgtc ccctacccct gtgtttttat     1860

ttctaaaaca atttgtgata ctaggaagat gcagatatca agtaaatgca ggtttattga     1920

acataactat tctagatgta atattttgac agtcttatta gaaaaccccc ttttttaaaa     1980

aaaatgtatg aaaccgataa ttaggacatt tgaaggagca gtagtttttt tttagtcctt     2040

taaaaaataa catctgtgac taataatttg agattaaaag atttgaagtc ttaatttatg     2100

tatgtttatt ccaaaaacag tttttgagtg tatgttctac aaagttctgc actagatact     2160

gttcaggaaa tagacaagta agatgtgtct atcctctaag acttccagtt tggtagctta     2220

gtatagaaat tctgtaacag aggtgcaggt gaaatgctgg gggaacagaa gggataagac     2280

catttatttt tctcaggaag gattgtggaa gacttcatag agtaagtggc attggagatt     2340

accttgaagt gaaggaagac aaagaaggaa aagagatgag gcataaagtg atgaaaccag     2400

gcacaagaaa gtgtgcggtg tgttctggga caaagaatgt tctgctactg tcgaataatg     2460

ggactaaagc tggcttgttc tggggaaagc tcatataagt atggatttta ttcctcaact     2520

agtaggatac caatactggt attgaaactt ggggaaaata actggagata ccagtgcagc     2580

tatttaaagc tgtagcaagg gctgcaatct tgcggagatt ttaaagagaa gttttaaagt     2640

ttctaatact gatgcctctt tttggtaaat acaagtttta taaatcctgc cctgggatcc     2700

tgattcccca ttaatcaaga tttgtcagac ttcaccttct ataattagaa aacacagtta     2760

taagaacagt caatttttta aattttccaa attaaaaaat tgcaccatga ttttgaacaa     2820

gcacttccaa ttacattacc catcttgtat gccataggtg ggagtataat tgtcacagcc     2880

tttaggaatg tagttttctg ggatttattg aaactttgaa ccttttggcc tactaagttc     2940

attcctagga aactgcctaa tgggaatgat ctgacaagtg tacacaagca aagtcattgc     3000

acctttgttc tttaatactt aaaactagcc caaatgccct gtcagtaagg gactggttta     3060

atagatggta cctttatgca atttgtttct aagtattcgt taagagagtg aggaatgtct     3120

ggattattag ggcaagattt ctaaacttgg gtaaaaaaaa aagttgtgca agcatttttg     3180

tggacaactt gatgctctaa aatataagta acaccacatt actaacagtg gctttgttag     3240

gaagcagaat tatggaagaa ctttcatggg tggctttaca tatttctata atgttttaat     3300

tttctataag catgtatttc gtaaacttaa ataaagaaaa aagaacacta cacttgcaaa     3360

aaaaaaaaaa aaaa                                                       3374


<210>  1664
<211>  2100
<212>  DNA
<213>  homo sapiens

<400>  1664
tttccttccc tctccctggg cttgggtctc ccacttgtcc agacagcggc cgggcttgtc       60

acggggctct gtgcagcctt ttccactctc ccggctgcca gcgtcccgcc ccgtcccctc      120

ccagccccca agggaggagg ggagagctgc agagaggagg aggggtcggg gaggccggct      180

ttataaaggc ggctggaaca accctgcccg ccagaccccg tcgcccggat cccctgagct      240

gcccgccatc ccacgtgacc gcgccgcccc ccagctccac cgctgagccc gctcgccatg      300

gccctcttcg gggccctctt cctagcgctg ctggcaggcg cacatgcaga gttcccaggc      360

tgcaagatcc gcgtcacctc caaggcgctg gagctggtga agcaggaggg gctgcgcttt      420

ctggagcaag agctggagac tatcaccatt ccggacctgc ggggcaaaga aggccacttc      480

tactacaaca tctctgaggt gaaggtcaca gagctgcaac tgacatcttc cgagctcgat      540

ttccagccac agcaggagct gatgcttcaa atcaccaatg cctccttggg gctgcgcttc      600

cggagacagc tgctctactg gttcttctat gatgggggct acatcaacgc ctcagctgag      660

ggtgtgtcca tccgcactgg tctggagctc tcccgggatc ccgctggacg gatgaaagtg      720

tccaatgtct cctgccaggc ctctgtctcc agaatgcacg cggccttcgg gggaaccttc      780

aagaaggtgt atgattttct ctccacgttc atcacctcag ggatgcgctt cctcctcaac      840

cagcagatct gccctgtcct ctaccacgca gggacggtcc tgctcaactc cctcctggac      900

accgtgcctg tgcgcagttc tgtggacgag cttgttggca ttgactattc cctcatgaag      960

gatcctgtgg cttccaccag caacctggac atggacttcc ggggggcctt cttccccctg     1020

actgagagga actggagcct ccccaaccgg gcagtggagc cccagctgca ggaggaagag     1080

cggatggtgt atgtggcctt ctctgagttc ttcttcgact ctgccatgga gagctacttc     1140

cgggcggggg ccctgcagct gttgctggtg ggggacaagg tgccccacga cctggacatg     1200

ctgctgaggg ccacctactt tgggagcatt gtcctgctga gcccagcagt gattgactcc     1260

ccattgaagc tggagctgcg ggtcctggcc ccaccgcgct gcaccatcaa gccctctggc     1320

accaccatct ctgtcactgc tagcgtcacc attgccctgg tcccaccaga ccagcctgag     1380

gtccagctgt ccagcatgac tatggacgcc cgtctcagcg ccaagatggc tctccggggg     1440

aaggccctgc gcacgcagct ggacctgcgc aggttccgaa tctattccaa ccattctgca     1500

ctggagtcgc tggctctgat cccattacag gcccctctga agaccatgct gcagattggg     1560

gtgatgccca tgctcaatga gcggacctgg cgtggggtgc agatcccact acctgagggc     1620

atcaactttg tgcatgaggt ggtgacgaac catgcgggat tcctcaccat cggggctgat     1680

ctccactttg ccaaagggct gcgagaggtg attgagaaga accggcctgc tgatgtcagg     1740

gcgtccactg cccccacacc gtccacagca gctgtctgag ccctcaatcc ccaagctggc     1800

agctgtcatt caggacccca acccctctca gcccctcttt tcccacattc atagcctgta     1860

gtgccccctc taacccccag tgccacagag aagacgggat ttgaagctgt acccaattta     1920

attccataat caatctatca attacagtcc gtccaccacc tccctgtggg ctgtcctgag     1980

ctctgttggg ttcctgggat ggaatcagtg catcataaag ggcattcttt aagcagagaa     2040

ggggccaggc caccccattc aggaactgct gcgggaataa agtgctaact tgcccccagg     2100


<210>  1665
<211>  1944
<212>  DNA
<213>  homo sapiens

<400>  1665
tttccttccc tctccctggg cttgggtctc ccacttgtcc agacagcggc cgggcttgtc       60

acggggctct gtgcagcctt ttccactctc ccggctgcca gcgtcccgcc ccgtcccctc      120

ccagccccca agggaggagg ggagagctgc agagaggagg aggggtcggg gaggccggct      180

ttataaaggc ggctggaaca accctgcccg ccagaccccg tcgcccggat cccctgagct      240

gcccgccatc ccacgtgacc gcgccgcccc ccagctccac cgctgagccc gctcgccatg      300

gccctcttcg gggccctctt cctagcgctg ctggcaggcg cacatgcaga gttcccaggc      360

tgcaagatcc gcgtcacctc caaggcgctg gagctggtga agcaggaggg gctgcgcttt      420

ctggagcaag agctggagac tatcaccatt ccggacctgc ggggcaaaga aggccacttc      480

tactacaaca tctctgaggt gaaggtcaca gagctgcaac tgacatcttc cgagctcgat      540

ttccagccac agcaggagct gatgcttcaa atcaccaatg cctccttggg gctgcgcttc      600

cggagacagc tgctctactg gttcttgaag gtgtatgatt ttctctccac gttcatcacc      660

tcagggatgc gcttcctcct caaccagcag atctgccctg tcctctacca cgcagggacg      720

gtcctgctca actccctcct ggacaccgtg cctgtgcgca gttctgtgga cgagcttgtt      780

ggcattgact attccctcat gaaggatcct gtggcttcca ccagcaacct ggacatggac      840

ttccgggggg ccttcttccc cctgactgag aggaactgga gcctccccaa ccgggcagtg      900

gagccccagc tgcaggagga agagcggatg gtgtatgtgg ccttctctga gttcttcttc      960

gactctgcca tggagagcta cttccgggcg ggggccctgc agctgttgct ggtgggggac     1020

aaggtgcccc acgacctgga catgctgctg agggccacct actttgggag cattgtcctg     1080

ctgagcccag cagtgattga ctccccattg aagctggagc tgcgggtcct ggccccaccg     1140

cgctgcacca tcaagccctc tggcaccacc atctctgtca ctgctagcgt caccattgcc     1200

ctggtcccac cagaccagcc tgaggtccag ctgtccagca tgactatgga cgcccgtctc     1260

agcgccaaga tggctctccg ggggaaggcc ctgcgcacgc agctggacct gcgcaggttc     1320

cgaatctatt ccaaccattc tgcactggag tcgctggctc tgatcccatt acaggcccct     1380

ctgaagacca tgctgcagat tggggtgatg cccatgctca atgagcggac ctggcgtggg     1440

gtgcagatcc cactacctga gggcatcaac tttgtgcatg aggtggtgac gaaccatgcg     1500

ggattcctca ccatcggggc tgatctccac tttgccaaag ggctgcgaga ggtgattgag     1560

aagaaccggc ctgctgatgt cagggcgtcc actgccccca caccgtccac agcagctgtc     1620

tgagccctca atccccaagc tggcagctgt cattcaggac cccaacccct ctcagcccct     1680

cttttcccac attcatagcc tgtagtgccc cctctaaccc ccagtgccac agagaagacg     1740

ggatttgaag ctgtacccaa tttaattcca taatcaatct atcaattaca gtccgtccac     1800

cacctccctg tgggctgtcc tgagctctgt tgggttcctg ggatggaatc agtgcatcat     1860

aaagggcatt ctttaagcag agaaggggcc aggccacccc attcaggaac tgctgcggga     1920

ataaagtgct aacttgcccc cagg                                            1944


<210>  1666
<211>  2100
<212>  DNA
<213>  homo sapiens

<400>  1666
tttccttccc tctccctggg cttgggtctc ccacttgtcc agacagcggc cgggcttgtc       60

acggggctct gtgcagcctt ttccactctc ccggctgcca gcgtcccgcc ccgtcccctc      120

ccagccccca agggaggagg ggagagctgc agagaggagg aggggtcggg gaggccggct      180

ttataaaggc ggctggaaca accctgcccg ccagaccccg tcgcccggat cccctgagct      240

gcccgccatc ccacgtgacc gcgccgcccc ccagctccac cgctgagccc gctcgccatg      300

gccctcttcg gggccctctt cctagcgctg ctggcaggcg cacatgcaga gttcccaggc      360

tgcaagatcc gcgtcacctc caaggcgctg gagctggtga agcaggaggg gctgcgcttt      420

ctggagcaag agctggagac tatcaccatt ccggacctgc ggggcaaaga aggccacttc      480

tactacaaca tctctgaggt gaaggtcaca gagctgcaac tgacatcttc cgagctcgat      540

ttccagccac agcaggagct gatgcttcaa atcaccaatg cctccttggg gctgcgcttc      600

cggagacagc tgctctactg gttcttctat gatgggggct acatcaacgc ctcagctgag      660

ggtgtgtcca tccgcactgg tctggagctc tcccgggatc ccgctggacg gatgaaagtg      720

tccaatgtct cctgccaggc ctctgtctcc agaatgcacg cggccttcgg gggaaccttc      780

aagaaggtgt atgattttct ctccacgttc atcacctcag ggatgcgctt cctcctcaac      840

cagcagatct gccctgtcct ctaccacgca gggacggtcc tgctcaactc cctcctggac      900

accgtgcctg tgcgcagttc tgtggacgag cttgttggca ttgactattc cctcatgaag      960

gatcctgtgg cttccaccag caacctggac atggacttcc ggggggcctt cttccccctg     1020

actgagagga actggagcct ccccaaccgg gcagtggagc cccagctgca ggaggaagag     1080

cggatggtgt atgtggcctt ctctgagttc ttcttcgact ctgccatgga gagctacttc     1140

cgggcggggg ccctgcagct gttgctggtg ggggacaagg tgccccacga cctggacatg     1200

ctgctgaggg ccacctactt tgggagcatt gtcctgctga gcccagcagt gattgactcc     1260

ccattgaagc tggagctgcg ggtcctggcc ccaccgcgct gcaccatcaa gccctctggc     1320

accaccatct ctgtcactgc tagcgtcacc attgccctgg tcccaccaga ccagcctgag     1380

gtccagctgt ccagcatgac tatggacgcc cgtctcagcg ccaagatggc tctccggggg     1440

aaggccctgc gcacgcagct ggacctgcgc aggttccgaa tctattccaa ccattctgca     1500

ctggagtcgc tggctctgat cccattacag gcccctctga agaccatgct gcagattggg     1560

gtgatgccca tgctcaatga gcggacctgg cgtggggtgc agatcccact acctgagggc     1620

atcaactttg tgcatgaggt ggtgacgaac catgcgggat tcctcaccat cggggctgat     1680

ctccactttg ccaaagggct gcgagaggtg attgagaaga accggcctgc tgatgtcagg     1740

gcgtccactg cccccacacc gtccacagca gctgtctgag ccctcaatcc ccaagctggc     1800

agctgtcatt caggacccca acccctctca gcccctcttt tcccacattc atagcctgta     1860

gtgccccctc taacccccag tgccacagag aagacgggat ttgaagctgt acccaattta     1920

attccataat caatctatca attacagtcc gtccaccacc tccctgtggg ctgtcctgag     1980

ctctgttggg ttcctgggat ggaatcagtg catcataaag ggcattcttt aagcagagaa     2040

ggggccaggc caccccattc aggaactgct gcgggaataa agtgctaact tgcccccagg     2100


<210>  1667
<211>  7331
<212>  DNA
<213>  homo sapiens

<400>  1667
gttgtgagct gcggcagaga ctggtggctg gaggagacgc cggcgctgga gagtgcgctg       60

cgccgcccgc cgctgaggga ccgcggggtt agccactgct ggctgcttcc agtgttcgcc      120

gagaggtacc gggggtgaca gctccgggac cggccgaaag gcgaggaacc ggtgtggaaa      180

ttaaaagaac acacatattt tgactggggc tttgatcaac caaatgctaa aaagccacat      240

aaagaagatc cctaatagtc atttctcaac aattatatag tcaactgatg taacaatggt      300

actaatattg ggacgcagac taaacagaga ggatcttggg gtgcgtgatt ccccagcaac      360

taagcgaaaa gtttttgaaa tggaccccaa atctctgaca ggtcatgagt tttttgactt      420

ctcttcagga tcatcccatg ccgaaaacat actccagata tttaatgaat ttcgtgatag      480

ccgcttattc acagatgtta tcatttgtgt ggaaggaaaa gaatttcctt gccatagagc      540

tgtgctctca gcctgtagca gctacttcag agctatgttt tgtaatgacc acagggaaag      600

ccgagaaatg ttggttgaga tcaatggtat tttagctgaa gctatggaat gttttttgca      660

gtatgtttat actggaaagg tgaagatcac tacagagaat gtacagtatc tctttgagac      720

atcaagcctc tttcagatta gtgttctccg tgatgcatgt gccaagttct tggaggagca      780

acttgatcct tgtaattgct taggaatcca gcgctttgct gatacccatt cactcaaaac      840

actcttcaca aaatgcaaaa attttgcgtt acagactttt gaggatgtat cccagcacga      900

agaatttctt gagcttgaca aagatgaact tattgattat atttgtagtg atgaacttgt      960

tattggtaaa gaggagatgg tttttgaagc cgtcatgcgt tgggtctatc gtgccgttga     1020

tctgagaaga ccactgttac acgagctcct gacacatgtg agactccctc tgttgcatcc     1080

caactacttt gttcaaacag ttgaagtgga ccaattgatc cagaattctc ctgagtgtta     1140

tcagttgttg catgaagcaa gacggtacca catacttggg aatgaaatga tgtccccaag     1200

gactaggcca cgcaggtcca ctggctattc tgaggtgata gttgtcgttg gaggatgtga     1260

gcgagttgga ggatttaatc ttccatacac tgagtgctac gatcctgtaa caggagaatg     1320

gaagtctttg gctaagcttc cagaatttac caaatcagag tatgcagtct gtgctctaag     1380

gaatgacatt cttgtttcag gtggaagaat caacagccgt gatgtctgga tttataactc     1440

acagttaaat atttggatca gagttgcctc tctcaataaa ggcagatggc gtcacaaaat     1500

ggctgtcctc cttggtaaag tatatgttgt cggtggctat gatgggcaaa acagacttag     1560

cagcgtagaa tgttatgatt ccttttcaaa tcgatggact gaagttgctc cccttaagga     1620

agccgtgagt tctcctgcag tgactagctg tgtaggcaaa ctgtttgtga ttggtggagg     1680

acctgatgat aatacttgtt ctgataaggt tcaatcttat gatccagaaa ccaattcttg     1740

gctacttcgt gcagctatcc caattgccaa aaggtgtata acagctgtat ccctaaacaa     1800

cctgatctat gttgccggtg gactgaccaa ggcaatatac tgttacgatc cagttgaaga     1860

ttactggatg cacgtacaga atacattcag ccgtcaggaa aactgtggta tgtctgtgtg     1920

taatggtaaa atatatatcc tgggcggaag acgggaaaat ggagaagcca cagacactat     1980

tctctgttat gatcctgcaa caagtatcat cacaggggta gctgcaatgc ccaggccagt     2040

gtcctatcat ggctgtgtga ctattcatag atacaatgag aaatgcttta aactctgaag     2100

acaggatacc tcaccgaaga agccacactg atccaagatg ggaggtttta aaaactctac     2160

agtgggaact tcacatatct cctttgtgcc atatgcaaaa aatagtaaaa ataataattt     2220

ggtgcctttc tcctcaaaat atcaatcttt caaactataa taaagccttt cctataattg     2280

aaaaaaaaaa cttttttgtt aaaggtaatg gtggttgtta cttggccttt gaagagtgta     2340

cctttgtaag tatttgtaag aagtctatgt gaattaggaa atgtctgtct gcataccttt     2400

taggagcgtg tgaatggtgt cttcacttat tatgtatgtt tatctgtatg tatattcctt     2460

attttgtcat atatgtagag aaaattgcat gacttgaggc atcatttagg ttgaagaagt     2520

taatgcttag gatgcattct aggagaaaaa atcagtttta aaaacctttg ttgttaacaa     2580

agtatatcca gattggttaa ttttattgaa gggttttttt ctgtaattga taaaaatgta     2640

atgacaacaa ttcaggcatc ataaaatact gaactattgt gactttattc ttagaattgc     2700

tgtcttacat taaacatgtt tttaggggga agttaggtag gagatagaaa aataagtgcc     2760

cctacaaggg ggattaaaat tacaagttaa ttcctaagag aaaaatggaa tggcctttga     2820

aggaaaaatg acccactatg gctctcaaag tttttatgca tcatctcttc aatcctctaa     2880

gaaagcctct tttcttaact tgataaagca gtggaaaccc attttgcaat attgttttgt     2940

gaaaaacagg gacagacagc caggtacaga gactcacacc tgtactccca actactcagc     3000

aggctggggc aggaggattg cttgagccca ggagtctgag gctacagtga gctatgaacg     3060

cacacggcac cctagcctgg gcaacaggtt gcgacactgt ctcaagagaa aagaaaaaga     3120

aaaataggga taggttttcc ttcctagccc agtagagttt gacctcatta gtatggtgct     3180

ttgggtgagg acctcttcct tgattatccc actttctagt gaacagctaa aattcctgag     3240

agtctctact gttaaggtac ctttaatagg ataaagcagg gaccacctat ctcagtgggt     3300

ccatttttct tttaaaatta gttatctgaa aaaacttagc agtagttccc atctttaagg     3360

taagtctttc atttggtccc cattgtgtaa aatactaatc aacattttca agcttctgta     3420

caacagactg cttttgtcta gatttctcaa ctccacttta taaagcttat cagttttcag     3480

agaggaatgt gaattttttt tctaatgcaa ataaatggat atggcaggaa ctacagcata     3540

agtgattatt gtgattctgg gtggacggat ataatttaca acatttaggg atgttctagg     3600

tagcctgctg tagtttgact tccagtcact gttgtctttc acattataat ttgtatattt     3660

cttgtgatag aagggatgat gcaaatatgt aattaaagtg tcaccagatt tctgttaaaa     3720

ccaaggttga aataaaaagc ctaacattgg taagctacat tgttttctca ttttagaatg     3780

attcagagat ttcagataga cattttttaa actttaatgc ttagctagaa tctacattct     3840

gaggaaaact ctaaaaaact taaaaatttt tagggaattt ttatttttca aatcataatt     3900

ttaaaatgat agataccatt ttgtgataac aacaattcag aaaacaattt tctatcctct     3960

tagttgaaag aatgtaggta cagtttggat acttgtactt taattttaga gtaaacatct     4020

gcattatact cttatagata atagaattat ttagttaaga aattctttac agtaaatgag     4080

ataatgtgtg aaaaagtatt ttgtaaatgc tgaggattct acaaatgata gttgttattt     4140

tcatgtgtat ttgtaagatc atgtccattt catgaatata ggacttcaca taaaaaaaga     4200

ctttctcaag acaactttat attctagtat ttttctgttg taaaaagtat taactattta     4260

cttttatttt gttatacatt tattttaata tccatgtgtt tattatagta aatttgaaat     4320

gaaatcctga aaaacagaat ttttttaaac acagacctca caccaatatt aattttttct     4380

ctacataatt taaaactaca taaattaagt acttaaaatt tatattgaag gccaccaaga     4440

acttaggttg aatcttagaa aatttaaata actattttta aagttaccca acttaatatt     4500

ttaatttttt aatatttatc ttcctttact aattcttgat aaataatagc attagacttg     4560

ataaaataaa aaagaatttt agagtagaat taatatatca aaaggggtat atcaaccaaa     4620

ttggtgtcag attgtattca ttctctcatc acataaagat ttttcttttg ataggtgatg     4680

ctcatatgaa cctttggttt agaatctata tatgtacatg tgtatgtatg tagatagtat     4740

ggttgtatac acacatatat accaaacacc atgaatttta gcagtctgtg atgatcagca     4800

aaaaagcaca taaagtaaaa attagttgac catgctaaat tcaattctgg aatttttttt     4860

tatttgggca tttctagaac tttttacatt tgaaagtaca tgatgagtat tagtaacgat     4920

gacttatgta taatcagaat ctttatgaca atttagtttt acaaggtcag aagagatgag     4980

tttgctaaac ccagctgtga tacctcagtt ggaaagggaa ttcaaaggta tgctttgtag     5040

aacagaaaag tatagttttt ttttcatgaa ctttaatcat tttctgtttt tcctctatgt     5100

gagtcagcta caaaagtggt ctaattttta caacagtaga acttcctcct tttctactgt     5160

aatcttccca ctgactttac tgcacaggta tgaaatacta gtgtattgga tcttcagtaa     5220

cctttttatt tcctagatga ttgaaatata ggtatttact ccatttaaac caggtgataa     5280

gatgatgtaa atactcaggg agggtattaa cttgttactt ttgctcgttt ggggtgtaaa     5340

gtgccatgac tgaataatct tcaattcatg attctagagt aagtttaatt tggaaaaagg     5400

ggcttcacac atggtggtgg ttgaacattg attcttttat acttaaaaag atgaaaatgt     5460

tttgtggact gatacatttt atcttactga atatgaattg tttatgtatc tctactgtca     5520

aatagccttt ttgaaactca ggaaagacaa aggttcaatt acaccacttt tgtcaataag     5580

caaaccaggt attttttttt tctcctgttg tctggatatg gcaatagatt ttttaaattg     5640

ctgtgagaac ccatatatga aaagagagga gttgaattgt gtgtgccttt tatgtcttga     5700

gatttatatg tggaaaagac gacatctact tcaaactgta tttttttcgt tttttttttt     5760

ttttggggaa ggggggagaa cggggtcttg ctctgtcgcc caggctggag tgcagtggcg     5820

cgatctcagc tgactgcaac ctccacctcc cgggttcaag ggattctgcc tcagcctccc     5880

gagtagctga gaccacaggt gcgtgccacc acacccggct aatttttttg tatttttagt     5940

agagacgggg tttagtagag acggatcact cctgaccacg tgatccgccc acctcggcct     6000

cccaaagtgc tgggattaca ggcgtgagcc accacccccg gcctgtattt tcagagagga     6060

gagcttggtg tttttgtggt gccaagtggt aagataatgt ctctttgagg cttcctatgg     6120

actgccttta ttttagtaaa ctcaagacac cagttaacct caacagagtt ttggccttat     6180

tagaatttgt tgtgcatctt attgaaagcc aggtttacat cacctcaccc cattattctt     6240

tttagttaaa taaatttacc atgccaagta accagaatgg agcaaattgg ttgatcttta     6300

aggcagtagg tttgactagc tagctatcat tattgtcaca tctaatgcta ggcaccagaa     6360

accatttgag ccaggagtgt gaatgaataa ttccagagac actttagaca ttttttaatg     6420

ttttatatga acattttaca tttgtgtgat tgccttagat attaaatttt cctagtgctg     6480

ataaaaacag caacattcat aacttatttt atatattgtt ccaaagaaaa gaatttgttt     6540

taatggtttc aaaataactg cacctgaatt tgtttatgtg ccttaagttc tctagtgcta     6600

tttcaacttt tttttcaatc taaatgaagc ttaccttaga taaggttcat atttgtttcc     6660

tatagagtaa ataaacttcc ccttcttaaa ttgtgtaata agcaccaacg tgtggttgct     6720

tggcagaatg agaatgttaa gggagattgt tggatgtttg gagtttcatt atattttttg     6780

tttttatttt ttgataccta ggtgcttttt aaaatattca gacaaatatc tatcttacat     6840

tgattaaacc cgtgtaaatt catttgcagt atctacatcg aatgtcaaaa aagtatactt     6900

atttttgttc catacttatg tacaattttt tccctcttca ggctttttca tttacctttt     6960

tgaaaaagca cttactctcc ccttccctat cacccctccc ccaaggtttc tttatttaaa     7020

tttttattga gagttgttgg agctctaaga caatacaaat ttagagttga acaaaagtat     7080

aatctgcttt acaactagta tagacctaag gtcatttgct ttcaattaga ggctccagag     7140

tcttcatagt ggaaagaatg ctttgtattt aattgttctt agttaagttg tagcacgtga     7200

atacttactt acatgttttg tttaaatata cttcttgcat agtttaattt tttaaaagtt     7260

gtatctaata aaatgtcttt taaccattat tacttgacta tatggttgta ttaaattttg     7320

tttacgaaaa a                                                          7331


<210>  1668
<211>  1952
<212>  DNA
<213>  homo sapiens

<400>  1668
atgcggcaag gccatgcgcc ggaggagtcg gagccgggct gcgaagcgcc gtgcgcgggt       60

ccgtgccacg cgcagcgcgt gctgcaggcc ctgaacgcct accggcggag cggcaccctc      120

accgacgtgg tgctgcgcgc cggcgggcgc gactttccgt gccaccgcgc ggcgctcagc      180

gcgggcagcg cctacttccg cagcttgttc gcggccgggc ggcccgagcg cggcccggcc      240

gtggtgccag tggtgccagt agctcccgag gcgccaggca cgagcccggc cggggcggcg      300

gcggcgctgg ccgtggtgct cgactacgtg tacggagcgg gcgtgcggct gcgcgcggag      360

gacgaggcgg cggccgtgct ggcgctggcg gagcggctgg gcgtggcggg cctgcgcgag      420

gcctgcgtgc gctttctcga gggccgcctg cgcgccgcca acagcctagc gctgcgccgc      480

gtggccgccg ccttctcgct ggccccgctg gccgagcgct gcggccgcgt cctgcgtcag      540

gccttcgccg aggtggcgcg ccacgccgac ttcctggagc tggcgcctga cgaggtggtg      600

gcgctgctgg cggaccccgc gctgggcgtg gcgcgcgagg aggccgtgtt tgaagcggcc      660

atgcgctggg tgcgccacga cgcgccggcc cgccgcggcc agctgcgacg cctgctggag      720

cacgtgcgcc tgccgctact ggcgcccgct tacttcctgg agaaggtgga ggcggacgag      780

ctgctgcagg cctgcggcga gtgccgcccg ctgctgctcg aggctcgcgc ctgcttcatc      840

ctgggccgcg aggccggtgc gctgcggacc cggccgcgga gattcatgga cctagctgaa      900

gtgatcgtgg tcatcggcgg ttgcgaccgc aaaggtctcc tgaagctgcc cttcgccgat      960

gcctaccatc cagagagcca gcggtggacc ccactgccca gcctgcccgg ctacactcgc     1020

tcagaattcg ccgcctgtgc tctccgcaat gacgtctacg tctccggagg ccacatcaac     1080

agtcatgatg tgtggatgtt tagctcccat ctgcacacct ggatcaaggt agcctctctg     1140

cacaagggca ggtggaggca caagatggca gttgtgcagg ggcagctgtt cgcggtgggt     1200

ggcttcgacg gcctgaggcg cctgcacagc gtggagcgct acgacccctt ctccaacacc     1260

tgggcggccg ccgcgcccct cccggaggcc gtgagctcgg cggcggtggc gtcctgcgcg     1320

ggcaagctct tcgtgattgg gggcgccagg cagggcggcg tcaacacgga caaggtgcag     1380

tgctttgacc ccaaggagga ccggtggagc ctgcggtcac cagcaccctt ctcacagcgg     1440

tgtctcgagg ctgtctccct tgaggacacc atctatgtca tggggggtct catgagcaaa     1500

atcttcacct atgatccagg cacagatgtg tggggggagg cagctgtcct ccccagccct     1560

gtggaaagct gtggagtcac tgtgtgtgac gggaaggtcc acatccttgg cgggcgggat     1620

gatcgcggag aaagcaccga taaggtcttc acctttgacc ccagcagtgg gcaggtggag     1680

gtccagccat ccctgcagcg ctgcaccagc tcccacggct gtgtcaccat catccagagc     1740

ttgggcaggt gattcagatt tggacagcct gagccaggag gcggagaggc aggcggagct     1800

cagatgcaca ctctgctccc tcatggcacc tccacgcaaa cagcccttaa cttaatggtc     1860

ccttttcttg tataaataaa atcttgttgg gtctgtgttc cagctgcagt ctgccctgcc     1920

tggagatgga atgtctaaaa aaaaaaaaaa aa                                   1952


<210>  1669
<211>  5880
<212>  DNA
<213>  homo sapiens

<400>  1669
gctagaaggc tacaagtatt cacagtgtat cataggcagt gggggagggg agagaaagca       60

agaaagactg ctctcggcac ttgtgctttt gttagttcta cagaagaggc agaaaaacaa      120

gagataacaa aggctccgtt tcctttctgt gagagaaggc ttttgtcttt cctcctgcta      180

cgatgtcagt gtctggcaag aaagagtttg atgtgaaaca gatcctaagg ctacgctgga      240

ggtggtttag tcatcctttt caaggttcca ccaacactgg aagctgtctt cagcaggaag      300

gatatgagca tagagggacc ccggttcagg gcaggttgaa gagccactct cgggacagaa      360

acggactgaa gaaaagcaac agtcctgtcc accacaatat actggcacca gtgccaggac      420

cggcccctgc ccatcagaga gccgttcaga atttgcagca acataatctg atagtacatt      480

ttcaagcaaa tgaagatact cctaaatcag ttccagagaa gaatttattc aaagaagctt      540

gtgagaaacg cgcacaagat ttggagatga tggctgatga caatatagaa gattctacag      600

caagattaga tacacaacac tctgaagaca tgaatgccac cagatctgaa gagcagttcc      660

atgttataaa ccacgcagag caaactcttc gtaaaatgga gaactacttg aaagagaaac      720

aactatgtga tgtgctactg attgcaggac acctccgcat cccagcccat aggttggttc      780

tcagcgcagt gtctgattat tttgctgcaa tgtttactaa tgatgtgctt gaagccaaac      840

aagaagaggt caggatggaa ggagtagatc caaatgcact aaattccttg gtgcagtatg      900

cttacacagg agtcctgcaa ttgaaagaag ataccattga aagtttgctg gctgcagctt      960

gtcttctgca gctgactcag gtcattgatg tttgctccaa ttttctcata aagcagctcc     1020

atccttcaaa ctgcttaggg attcgatcat ttggagatgc ccaaggctgt acagaacttc     1080

tgaacgtggc acacaaatac actatggaac acttcattga ggtaataaaa aaccaagaat     1140

tcctcctgct tccagctaat gaaatttcaa aacttctgtg cagtgatgac attaatgtgc     1200

ctgatgaaga gaccattttt catgctctaa tgcagtgggt ggggcatgat gtgcagaata     1260

ggcaaggaga actggggatg ctgctttctt acatcagact gccattactc ccaccacagt     1320

tactggcaga tcttgaaacc agttccatgt ttactggtga tcttgagtgt cagaagctcc     1380

tgatggaagc tatgaagtat catcttttgc ctgagagaag atccatgatg caaagccctc     1440

ggacaaagcc tagaaaatca actgtggggg cactttatgc tgtaggaggc atggatgcta     1500

tgaaaggtac tactactatt gaaaaatatg acctcaggac caacagttgg ctacatattg     1560

gcaccatgaa tggccgtagg cttcaatttg gagtcgcagt tattgataat aagctctatg     1620

tcgtgggagg aagagacggt ttaaaaactt tgaatacagt ggaatgtttt aatccagttg     1680

gcaaaatctg gactgtgatg cctcccatgt caacacatcg gcacggctta ggtgtagcca     1740

ctcttgaagg accaatgtat gctgtaggtg gtcatgatgg atggagctat ctaaatactg     1800

tagaaagatg ggaccctgag ggacgacagt ggaattacgt agccagtatg tcaactccta     1860

gaagcacagt tggtgttgtt gcattaaaca acaaattata tgctattggt ggacgtgatg     1920

gaagttcctg cctcaaatca atggaatact ttgacccaca cactaacaag tggagtttgt     1980

gtgctccaat gtccaaaaga cgtggaggtg tgggagttgc cacatacaat ggattcttat     2040

atgttgtagg ggggcatgat gcccctgctt ccaaccattg ctccaggctt tctgactgtg     2100

tggaacggta tgatccaaaa ggtgattcat ggtcaactgt ggcacctctg agtgttcctc     2160

gagatgctgt tgctgtgtgc cctcttggag acaaactcta cgtggttgga ggatatgacg     2220

gacatactta tttgaacaca gttgagtcat atgatgcaca gagaaatgaa tggaaagagg     2280

aagttcctgt taacattgga agagctggtg catgtgttgt agtggtgaag ctaccctaaa     2340

gctatctatc tttatcaaat ggaatgaaac tagataattt caagaaactg agtaggacaa     2400

agggagaaag aaatacatgt tctttttcct gcaattaata atcagactgg aaaattgttg     2460

tatcatttta atttgtagtt acaattgctt tcattcgtga agccgaaacg tttttaaaca     2520

tgaattacat atgaattatt aagcatatgt gctttcgcag ctgataatat aaaaggaaat     2580

cccacagtct agatatagcc ccattactac aaaatgctaa aatatttaat gaaaattgat     2640

ggtggccaca gtgtgcaggt tataaaagca ttaatacatt tcaaggtaag agccttaaaa     2700

gttaaaaaca ttttcagttt ttttttaaaa aacgtactct tattatctgg aacatagaaa     2760

tataaaaggt aacatctaaa gcttagaata gtgtgatttt tagtaagcca ttattctcct     2820

attcaaataa tatcccaaag agctaaacaa ttccttacat ttaccaagag gaaagctttt     2880

actgtgttga agctaaaaaa ataatggctc tttgacaaaa cttgttatgt tgatcgcggt     2940

atgtcaaaat ttttacaggt ttgctcatct gccagagcac acatataaat ttggtatttc     3000

ttaacatatt atcttgttag atttgttacc agtaaaatat tactgtaatt tcatatacac     3060

agtctataca atgaaataat gaatatttat catattgata caaactgtga cctcagcttc     3120

agagtgtcag ggcctcactt gtatagaatg taatgttctc ctcaaacatt tatgttaact     3180

ctataaacaa atatcgttaa gttaaacaag ttttcaaaaa caaaacaatt tttaaagtac     3240

cttaaaattg aggatgttac tcagtgttaa cacatgggaa caccaaaata ttcaataagc     3300

ctggtcaatt ctatagttat cttttttgta ccaacacatg cttttctgtt actgttatat     3360

tatccagtag aaaatgttag gatatgtgtg ctatataaaa aaaaaaaaag acttgttaag     3420

ttttaaaata acaaaaatgg ctagttgaat agtattttat gtgtaattct tccatttatt     3480

ctgtttaatt atacaactaa gatgaaatat tgaaaaaccc tttgtgaaag taacttttca     3540

agtaaatgca caactttaga atttctacaa ataagttctt ttaaacagtc tttttattgt     3600

ggattgtgaa atcaaaatct ggagaaatgc ttataaaata tactactagc ttttaagttt     3660

taagaaagaa gaacgtaagt tgtacaaaga tatttgtact ttgacaaact gaatttaaat     3720

aaactttatt tcctctcact atagtgtggc tttagaatat atcaagtaca acctgaatgg     3780

actttttgat tttacatttc ctatatcact aaaatactta aacacaaaaa taaaattcca     3840

ctcctttatt tcttcttaca cctgccattg tctctaattc taaagagaga gctatagatt     3900

tctgcagttc tagaggtgaa gatagagaca tagagaggct gtgaaacaca catacagccc     3960

tgttaggtct tttgaattca caccttattg aaatcagtgt agaagtagag ttacctaaac     4020

ctttatcgcc aatgcacagc ttggcctgtt aagttaaatg tgggtgtcaa ccagtggaaa     4080

agatcaaagg accttttgca gcctagcttg ccaatcttcc agtaacaacg aggtgctacc     4140

aataggcaga ctgtgtctag agtcatgcat ggacaagagg aaagtgaaag ttgaatactc     4200

tcttctcaat ggcatagctg gacttgatta agtattgact catagaagag acatgtatgt     4260

ttcccggggc taccccttca tagctgcatt taaaaatggt gttcaggcca ctatggctgc     4320

tgtggtttga atattttttt ccctcgaaaa ctcatgttga aacttaactc ctaatgtagc     4380

agtactgaga ggcagggccc ttaagaggtg attgggccat gaggtctgtg ccctcctgaa     4440

tggattaatc cattcatgga ttaatggatt attatgagtg ggggactggt gactttatat     4500

gaaaaggaag gaagagtgac ctaagctagc atgctcaggg tgcaccgtat gtcccctggt     4560

catgtgatgc tatgtgttac cttgggactt acctgacagc tcttaccaac aagaaggcca     4620

tcccagatat ggcctctcaa cctcagactt ctcagcctgc ctaactgtaa gaaattaatt     4680

ctttttcttt ataaattacc caggttctgt tttaagcctc agaaaatgaa ctaagacaat     4740

gccctagatg agctgccaaa atctgagcag atatgagcca tcagaataga gacctgcaga     4800

ggcccagggc actcaaacat aactgtgctt gtctcagtca aacttaattg ggaaaaggag     4860

gagtaagagc aggccctttc tgacatgctt tagcagagat aacttatcag ggctagttta     4920

aacaaatgtg tataggaaag gatgttattt atatattctt acaagagtgt aagggctcac     4980

acatttactg tactcagatc tgaaagacaa tgttgcttct tgattttttt ctataatcac     5040

tatgaccgtg ttcacgattc cctactctgc aactctcagc atgcatcatg atgattctct     5100

aacactgtct gtcaccttcc tgtatttcca cagagcatgc aagaacttct acaaaacttc     5160

tataccacac agaagctgaa agagactctg gggcactaaa ttcagatcct ttctccacac     5220

agcaatgaca tttatcaatc tgactcaggt gtggctgttg cccctttttg atatggaggg     5280

aacactgaaa gacagtttcc ttctggagtt ccaaatgcaa tatagaaaaa aaaaccctgt     5340

gactctggat tttattttaa gttctctaac aagactccta ccttgagatc ttagtctagg     5400

taaagaaaaa aaaaaaaagg tcatgaaaca caaatgtcct caactgtcat cattctatgt     5460

ttactttctc ccaatcacat cacctgaggt agaagagatt tttcagttgc tatttctctt     5520

cgtaatgaat tttctttaca tcctgtccac actgctggag atactaagtc ccaacctaaa     5580

tgatggaagg agcatctccc ctcttgtctg tggaagatat cacatgaact acctaatttt     5640

caagcatgga tctccatatt tcaaaggaaa gttttaaaaa tgtttttaaa acttcaaata     5700

tctcaccaca gtgaattatg ggtaaggtga taatatgttt aattagcttg atttaatcat     5760

cccacactgt atacatatgc caaaatatca ttttgtatgc cataatatat atgatttatg     5820

aattatagta atattaataa aagtgttaaa gctttaaaaa aaaaaaaaaa aaaaaaaaaa     5880


<210>  1670
<211>  2547
<212>  DNA
<213>  homo sapiens

<400>  1670
gctagaaggc tacaagtatt cacagtgtat cataggcagt gggggagggg agagaaagca       60

agaaagactg ctctcggcac ttgtgctttt gttagttcta cagaagaggc agaaaaacaa      120

gagataacaa aggctccgtt tcctttctgt gagagaaggc ttttgtcttt cctcctgcta      180

cgatgtcagt gtctggcaag aaagagtttg atgtgaaaca gatcctaagg ctacgctgga      240

ggtggtttag tcatcctttt caaggttcca ccaacactgg aagctgtctt cagcaggaag      300

gatatgagca tagagggacc ccggttcagg gcaggttgaa gagccactct cgggacagaa      360

acggactgaa gaaaagcaac agtcctgtcc accacaatat actggcacca gtgccaggac      420

cggcccctgc ccatcagaga gccgttcaga atttgcagca acataatctg atagtacatt      480

ttcaagcaaa tgaagatact cctaaatcag ttccagagaa gaatttattc aaagaagctt      540

gtgagaaacg cgcacaagat ttggagatga tggctgatga caatatagaa gattctacag      600

caagattaga tacacaacac tctgaagaca tgaatgccac cagatctgaa gagcagttcc      660

atgttataaa ccacgcagag caaactcttc gtaaaatgga gaactacttg aaagagaaac      720

aactatgtga tgtgctactg attgcaggac acctccgcat cccagcccat aggttggttc      780

tcagcgcagt gtctgattat tttgctgcaa tgtttactaa tgatgtgctt gaagccaaac      840

aagaagaggt caggatggaa ggagtagatc caaatgcact aaattccttg gtgcagtatg      900

cttacacagg agtcctgcaa ttgaaagaag ataccattga aagtttgctg gctgcagctt      960

gtcttctgca gctgactcag gtcattgatg tttgctccaa ttttctcata aagcagctcc     1020

atccttcaaa ctgcttaggg attcgatcat ttggagatgc ccaaggctgt acagaacttc     1080

tgaacgtggc acacaaatac actatggaac acttcattga ggtaataaaa aaccaagaat     1140

tcctcctgct tccagctaat gaaatttcaa aacttctgtg cagtgatgac attaatgtgc     1200

ctgatgaaga gaccattttt catgctctaa tgcagtgggt ggggcatgat gtgcagaata     1260

ggcaaggaga actggggatg ctgctttctt acatcagact gccattactc ccaccacagt     1320

tactggcaga tcttgaaacc agttccatgt ttactggtga tcttgagtgt cagaagctcc     1380

tgatggaagc tatgaagtat catcttttgc ctgagagaag atccatgatg caaagccctc     1440

ggacaaagcc tagaaaatca actgtggggg cactttatgc tgtaggaggc atggatgcta     1500

tgaaaggtac tactactatt gaaaaatatg acctcaggac caacagttgg ctacatattg     1560

gcaccatgaa tggccgtagg cttcaatttg gagtcgcagt tattgataat aagctctatg     1620

tcgtgggagg aagagacggt ttaaaaactt tgaatacagt ggaatgtttt aatccagttg     1680

gcaaaatctg gactgtgatg cctcccatgt caacacatcg gcacggctta ggtgtagcca     1740

ctcttgaagg accaatgtat gctgtaggtg gtcatgatgg atggagctat ctaaatactg     1800

tagaaagatg ggaccctgag ggacgacagt ggaattacgt agccagtatg tcaactccta     1860

gaagcacagt tggtgttgtt gcattaaaca acaaattata tgctattggt ggacgtgatg     1920

gaagttcctg cctcaaatca atggaatact ttgacccaca cactaacaag tggagtttgt     1980

gtgctccaat gtccaaaaga cgtggaggtg tgggagttgc cacatacaat ggattcttat     2040

atgttgtagg ggggcatgat gcccctgctt ccaaccattg ctccaggctt tctgactgtg     2100

tggaacggta tgatccaaaa ggtgattcat ggtcaactgt ggcacctctg agtgttcctc     2160

gagatgctgt tgctgtgtgc cctcttggag acaaactcta cgtggttgga ggatatgacg     2220

gacatactta tttgaacaca gttgagtcat atgatgcaca gagaaatgaa tggaaagaga     2280

gcatgcaaga acttctacaa aacttctata ccacacagaa gctgaaagag actctggggc     2340

actaaattca gatcctttct ccacacagca atgacattta tcaatctgac tcaggtgtgg     2400

ctgttgcccc tttttgatat ggagggaaca ctgaaagaca gtttccttct ggagttccaa     2460

atgcaatata gaaaaaaaaa ccctgtgact ctggatttta ttttaagttc tctaacaaga     2520

ctcctacctt gagatcttag tctaggt                                         2547


<210>  1671
<211>  5880
<212>  DNA
<213>  homo sapiens

<400>  1671
gctagaaggc tacaagtatt cacagtgtat cataggcagt gggggagggg agagaaagca       60

agaaagactg ctctcggcac ttgtgctttt gttagttcta cagaagaggc agaaaaacaa      120

gagataacaa aggctccgtt tcctttctgt gagagaaggc ttttgtcttt cctcctgcta      180

cgatgtcagt gtctggcaag aaagagtttg atgtgaaaca gatcctaagg ctacgctgga      240

ggtggtttag tcatcctttt caaggttcca ccaacactgg aagctgtctt cagcaggaag      300

gatatgagca tagagggacc ccggttcagg gcaggttgaa gagccactct cgggacagaa      360

acggactgaa gaaaagcaac agtcctgtcc accacaatat actggcacca gtgccaggac      420

cggcccctgc ccatcagaga gccgttcaga atttgcagca acataatctg atagtacatt      480

ttcaagcaaa tgaagatact cctaaatcag ttccagagaa gaatttattc aaagaagctt      540

gtgagaaacg cgcacaagat ttggagatga tggctgatga caatatagaa gattctacag      600

caagattaga tacacaacac tctgaagaca tgaatgccac cagatctgaa gagcagttcc      660

atgttataaa ccacgcagag caaactcttc gtaaaatgga gaactacttg aaagagaaac      720

aactatgtga tgtgctactg attgcaggac acctccgcat cccagcccat aggttggttc      780

tcagcgcagt gtctgattat tttgctgcaa tgtttactaa tgatgtgctt gaagccaaac      840

aagaagaggt caggatggaa ggagtagatc caaatgcact aaattccttg gtgcagtatg      900

cttacacagg agtcctgcaa ttgaaagaag ataccattga aagtttgctg gctgcagctt      960

gtcttctgca gctgactcag gtcattgatg tttgctccaa ttttctcata aagcagctcc     1020

atccttcaaa ctgcttaggg attcgatcat ttggagatgc ccaaggctgt acagaacttc     1080

tgaacgtggc acacaaatac actatggaac acttcattga ggtaataaaa aaccaagaat     1140

tcctcctgct tccagctaat gaaatttcaa aacttctgtg cagtgatgac attaatgtgc     1200

ctgatgaaga gaccattttt catgctctaa tgcagtgggt ggggcatgat gtgcagaata     1260

ggcaaggaga actggggatg ctgctttctt acatcagact gccattactc ccaccacagt     1320

tactggcaga tcttgaaacc agttccatgt ttactggtga tcttgagtgt cagaagctcc     1380

tgatggaagc tatgaagtat catcttttgc ctgagagaag atccatgatg caaagccctc     1440

ggacaaagcc tagaaaatca actgtggggg cactttatgc tgtaggaggc atggatgcta     1500

tgaaaggtac tactactatt gaaaaatatg acctcaggac caacagttgg ctacatattg     1560

gcaccatgaa tggccgtagg cttcaatttg gagtcgcagt tattgataat aagctctatg     1620

tcgtgggagg aagagacggt ttaaaaactt tgaatacagt ggaatgtttt aatccagttg     1680

gcaaaatctg gactgtgatg cctcccatgt caacacatcg gcacggctta ggtgtagcca     1740

ctcttgaagg accaatgtat gctgtaggtg gtcatgatgg atggagctat ctaaatactg     1800

tagaaagatg ggaccctgag ggacgacagt ggaattacgt agccagtatg tcaactccta     1860

gaagcacagt tggtgttgtt gcattaaaca acaaattata tgctattggt ggacgtgatg     1920

gaagttcctg cctcaaatca atggaatact ttgacccaca cactaacaag tggagtttgt     1980

gtgctccaat gtccaaaaga cgtggaggtg tgggagttgc cacatacaat ggattcttat     2040

atgttgtagg ggggcatgat gcccctgctt ccaaccattg ctccaggctt tctgactgtg     2100

tggaacggta tgatccaaaa ggtgattcat ggtcaactgt ggcacctctg agtgttcctc     2160

gagatgctgt tgctgtgtgc cctcttggag acaaactcta cgtggttgga ggatatgacg     2220

gacatactta tttgaacaca gttgagtcat atgatgcaca gagaaatgaa tggaaagagg     2280

aagttcctgt taacattgga agagctggtg catgtgttgt agtggtgaag ctaccctaaa     2340

gctatctatc tttatcaaat ggaatgaaac tagataattt caagaaactg agtaggacaa     2400

agggagaaag aaatacatgt tctttttcct gcaattaata atcagactgg aaaattgttg     2460

tatcatttta atttgtagtt acaattgctt tcattcgtga agccgaaacg tttttaaaca     2520

tgaattacat atgaattatt aagcatatgt gctttcgcag ctgataatat aaaaggaaat     2580

cccacagtct agatatagcc ccattactac aaaatgctaa aatatttaat gaaaattgat     2640

ggtggccaca gtgtgcaggt tataaaagca ttaatacatt tcaaggtaag agccttaaaa     2700

gttaaaaaca ttttcagttt ttttttaaaa aacgtactct tattatctgg aacatagaaa     2760

tataaaaggt aacatctaaa gcttagaata gtgtgatttt tagtaagcca ttattctcct     2820

attcaaataa tatcccaaag agctaaacaa ttccttacat ttaccaagag gaaagctttt     2880

actgtgttga agctaaaaaa ataatggctc tttgacaaaa cttgttatgt tgatcgcggt     2940

atgtcaaaat ttttacaggt ttgctcatct gccagagcac acatataaat ttggtatttc     3000

ttaacatatt atcttgttag atttgttacc agtaaaatat tactgtaatt tcatatacac     3060

agtctataca atgaaataat gaatatttat catattgata caaactgtga cctcagcttc     3120

agagtgtcag ggcctcactt gtatagaatg taatgttctc ctcaaacatt tatgttaact     3180

ctataaacaa atatcgttaa gttaaacaag ttttcaaaaa caaaacaatt tttaaagtac     3240

cttaaaattg aggatgttac tcagtgttaa cacatgggaa caccaaaata ttcaataagc     3300

ctggtcaatt ctatagttat cttttttgta ccaacacatg cttttctgtt actgttatat     3360

tatccagtag aaaatgttag gatatgtgtg ctatataaaa aaaaaaaaag acttgttaag     3420

ttttaaaata acaaaaatgg ctagttgaat agtattttat gtgtaattct tccatttatt     3480

ctgtttaatt atacaactaa gatgaaatat tgaaaaaccc tttgtgaaag taacttttca     3540

agtaaatgca caactttaga atttctacaa ataagttctt ttaaacagtc tttttattgt     3600

ggattgtgaa atcaaaatct ggagaaatgc ttataaaata tactactagc ttttaagttt     3660

taagaaagaa gaacgtaagt tgtacaaaga tatttgtact ttgacaaact gaatttaaat     3720

aaactttatt tcctctcact atagtgtggc tttagaatat atcaagtaca acctgaatgg     3780

actttttgat tttacatttc ctatatcact aaaatactta aacacaaaaa taaaattcca     3840

ctcctttatt tcttcttaca cctgccattg tctctaattc taaagagaga gctatagatt     3900

tctgcagttc tagaggtgaa gatagagaca tagagaggct gtgaaacaca catacagccc     3960

tgttaggtct tttgaattca caccttattg aaatcagtgt agaagtagag ttacctaaac     4020

ctttatcgcc aatgcacagc ttggcctgtt aagttaaatg tgggtgtcaa ccagtggaaa     4080

agatcaaagg accttttgca gcctagcttg ccaatcttcc agtaacaacg aggtgctacc     4140

aataggcaga ctgtgtctag agtcatgcat ggacaagagg aaagtgaaag ttgaatactc     4200

tcttctcaat ggcatagctg gacttgatta agtattgact catagaagag acatgtatgt     4260

ttcccggggc taccccttca tagctgcatt taaaaatggt gttcaggcca ctatggctgc     4320

tgtggtttga atattttttt ccctcgaaaa ctcatgttga aacttaactc ctaatgtagc     4380

agtactgaga ggcagggccc ttaagaggtg attgggccat gaggtctgtg ccctcctgaa     4440

tggattaatc cattcatgga ttaatggatt attatgagtg ggggactggt gactttatat     4500

gaaaaggaag gaagagtgac ctaagctagc atgctcaggg tgcaccgtat gtcccctggt     4560

catgtgatgc tatgtgttac cttgggactt acctgacagc tcttaccaac aagaaggcca     4620

tcccagatat ggcctctcaa cctcagactt ctcagcctgc ctaactgtaa gaaattaatt     4680

ctttttcttt ataaattacc caggttctgt tttaagcctc agaaaatgaa ctaagacaat     4740

gccctagatg agctgccaaa atctgagcag atatgagcca tcagaataga gacctgcaga     4800

ggcccagggc actcaaacat aactgtgctt gtctcagtca aacttaattg ggaaaaggag     4860

gagtaagagc aggccctttc tgacatgctt tagcagagat aacttatcag ggctagttta     4920

aacaaatgtg tataggaaag gatgttattt atatattctt acaagagtgt aagggctcac     4980

acatttactg tactcagatc tgaaagacaa tgttgcttct tgattttttt ctataatcac     5040

tatgaccgtg ttcacgattc cctactctgc aactctcagc atgcatcatg atgattctct     5100

aacactgtct gtcaccttcc tgtatttcca cagagcatgc aagaacttct acaaaacttc     5160

tataccacac agaagctgaa agagactctg gggcactaaa ttcagatcct ttctccacac     5220

agcaatgaca tttatcaatc tgactcaggt gtggctgttg cccctttttg atatggaggg     5280

aacactgaaa gacagtttcc ttctggagtt ccaaatgcaa tatagaaaaa aaaaccctgt     5340

gactctggat tttattttaa gttctctaac aagactccta ccttgagatc ttagtctagg     5400

taaagaaaaa aaaaaaaagg tcatgaaaca caaatgtcct caactgtcat cattctatgt     5460

ttactttctc ccaatcacat cacctgaggt agaagagatt tttcagttgc tatttctctt     5520

cgtaatgaat tttctttaca tcctgtccac actgctggag atactaagtc ccaacctaaa     5580

tgatggaagg agcatctccc ctcttgtctg tggaagatat cacatgaact acctaatttt     5640

caagcatgga tctccatatt tcaaaggaaa gttttaaaaa tgtttttaaa acttcaaata     5700

tctcaccaca gtgaattatg ggtaaggtga taatatgttt aattagcttg atttaatcat     5760

cccacactgt atacatatgc caaaatatca ttttgtatgc cataatatat atgatttatg     5820

aattatagta atattaataa aagtgttaaa gctttaaaaa aaaaaaaaaa aaaaaaaaaa     5880


<210>  1672
<211>  2547
<212>  DNA
<213>  homo sapiens

<400>  1672
gctagaaggc tacaagtatt cacagtgtat cataggcagt gggggagggg agagaaagca       60

agaaagactg ctctcggcac ttgtgctttt gttagttcta cagaagaggc agaaaaacaa      120

gagataacaa aggctccgtt tcctttctgt gagagaaggc ttttgtcttt cctcctgcta      180

cgatgtcagt gtctggcaag aaagagtttg atgtgaaaca gatcctaagg ctacgctgga      240

ggtggtttag tcatcctttt caaggttcca ccaacactgg aagctgtctt cagcaggaag      300

gatatgagca tagagggacc ccggttcagg gcaggttgaa gagccactct cgggacagaa      360

acggactgaa gaaaagcaac agtcctgtcc accacaatat actggcacca gtgccaggac      420

cggcccctgc ccatcagaga gccgttcaga atttgcagca acataatctg atagtacatt      480

ttcaagcaaa tgaagatact cctaaatcag ttccagagaa gaatttattc aaagaagctt      540

gtgagaaacg cgcacaagat ttggagatga tggctgatga caatatagaa gattctacag      600

caagattaga tacacaacac tctgaagaca tgaatgccac cagatctgaa gagcagttcc      660

atgttataaa ccacgcagag caaactcttc gtaaaatgga gaactacttg aaagagaaac      720

aactatgtga tgtgctactg attgcaggac acctccgcat cccagcccat aggttggttc      780

tcagcgcagt gtctgattat tttgctgcaa tgtttactaa tgatgtgctt gaagccaaac      840

aagaagaggt caggatggaa ggagtagatc caaatgcact aaattccttg gtgcagtatg      900

cttacacagg agtcctgcaa ttgaaagaag ataccattga aagtttgctg gctgcagctt      960

gtcttctgca gctgactcag gtcattgatg tttgctccaa ttttctcata aagcagctcc     1020

atccttcaaa ctgcttaggg attcgatcat ttggagatgc ccaaggctgt acagaacttc     1080

tgaacgtggc acacaaatac actatggaac acttcattga ggtaataaaa aaccaagaat     1140

tcctcctgct tccagctaat gaaatttcaa aacttctgtg cagtgatgac attaatgtgc     1200

ctgatgaaga gaccattttt catgctctaa tgcagtgggt ggggcatgat gtgcagaata     1260

ggcaaggaga actggggatg ctgctttctt acatcagact gccattactc ccaccacagt     1320

tactggcaga tcttgaaacc agttccatgt ttactggtga tcttgagtgt cagaagctcc     1380

tgatggaagc tatgaagtat catcttttgc ctgagagaag atccatgatg caaagccctc     1440

ggacaaagcc tagaaaatca actgtggggg cactttatgc tgtaggaggc atggatgcta     1500

tgaaaggtac tactactatt gaaaaatatg acctcaggac caacagttgg ctacatattg     1560

gcaccatgaa tggccgtagg cttcaatttg gagtcgcagt tattgataat aagctctatg     1620

tcgtgggagg aagagacggt ttaaaaactt tgaatacagt ggaatgtttt aatccagttg     1680

gcaaaatctg gactgtgatg cctcccatgt caacacatcg gcacggctta ggtgtagcca     1740

ctcttgaagg accaatgtat gctgtaggtg gtcatgatgg atggagctat ctaaatactg     1800

tagaaagatg ggaccctgag ggacgacagt ggaattacgt agccagtatg tcaactccta     1860

gaagcacagt tggtgttgtt gcattaaaca acaaattata tgctattggt ggacgtgatg     1920

gaagttcctg cctcaaatca atggaatact ttgacccaca cactaacaag tggagtttgt     1980

gtgctccaat gtccaaaaga cgtggaggtg tgggagttgc cacatacaat ggattcttat     2040

atgttgtagg ggggcatgat gcccctgctt ccaaccattg ctccaggctt tctgactgtg     2100

tggaacggta tgatccaaaa ggtgattcat ggtcaactgt ggcacctctg agtgttcctc     2160

gagatgctgt tgctgtgtgc cctcttggag acaaactcta cgtggttgga ggatatgacg     2220

gacatactta tttgaacaca gttgagtcat atgatgcaca gagaaatgaa tggaaagaga     2280

gcatgcaaga acttctacaa aacttctata ccacacagaa gctgaaagag actctggggc     2340

actaaattca gatcctttct ccacacagca atgacattta tcaatctgac tcaggtgtgg     2400

ctgttgcccc tttttgatat ggagggaaca ctgaaagaca gtttccttct ggagttccaa     2460

atgcaatata gaaaaaaaaa ccctgtgact ctggatttta ttttaagttc tctaacaaga     2520

ctcctacctt gagatcttag tctaggt                                         2547


<210>  1673
<211>  4412
<212>  DNA
<213>  homo sapiens

<400>  1673
agccgctaag gccgctccca ccccgtggta tcctgggact aggcttttcc ggaaggagcg       60

gctcggtgtt ggggctaggc cggtattcta ggcccaagcc caggcccagg cctgtgttcc      120

cggcccttgc tcaaagacag gccggtggcc gctgcgacac tctaggtaca gcggagggcg      180

cagcgggccg ttcgctgagg tgtccggacc cgccgccgag cgggccgtgg agccacagta      240

cgtggcggcg cctcttcctt gcccgaagcg gaactgctga aggagcggca gcgcaggccg      300

gacgaggtga accaggtcat ttaaccgcct tcaggtgatg aatcatctgt ctaataatca      360

gatttgaggt ccacagccct ttgtggtcct gctacagggt gattttcagt ggatgactga      420

ctggcgtggc ccgaggggtg ccgcagtgac tgccttccct tgataaggaa acgagctttc      480

tgttctttct ggacacctcg ttacctgtaa aacattccgg ttataacttc tttatccggc      540

ttgcatctct gtgcaagagg aaagctttca catgaaagtg tcccttggta acggcgaaat      600

gggcgtctct gcccatttgc agccttgtaa ggcaggaacc acacgctttt ttaccagcaa      660

tactcacagt tcggtggtat tgcaaggctt tgatcagctt agaatagaag gattgctttg      720

tgatgtgacc ctggtaccag gtgatggaga tgaaatcttc cctgttcaca gagctatgat      780

ggcgtctgct agtgattatt tcaaagccat gttcacaggt ggaatgaaag aacaagattt      840

gatgtgcatt aagcttcatg gggtgaacaa ggttggtctg aagaaaatca ttgattttat      900

ttatactgca aaactttctc ttaatatgga caatcttcag gacacacttg aagctgctag      960

ctttttacaa atattacccg ttttggattt ctgtaaagta tttcttatat caggagtctc     1020

tttggataac tgtgttgagg ttggacgaat tgctaacacc tacaatctta tagaagtgga     1080

taaatatgtt aataatttca tcctgaagaa ctttcctgct ttattgagta ctggggagtt     1140

tctaaaactc ccttttgaac gacttgcatt tgtgctttcc agtaatagtc ttaagcactg     1200

taccgaactt gaactcttta aggcagcctg tcgctggcta aggttggaag accctcggat     1260

ggattatgct gcaaagttaa tgaagaatat tcgatttcca ctgatgacac cacaggatct     1320

catcaattac gtgcagacag tagatttcat gagaacagac aatacctgcg tgaatttgct     1380

tttggaagct agcaattacc aaatgatgcc atatatgcag ccagtgatgc agtcagatag     1440

aactgccatt cgatctgact ccactcactt ggttacatta ggaggagttt tgaggcagca     1500

gctggttgtc agtaaagaat tacggatgta tgatgaaagg gcacaagaat ggagatcttt     1560

agccccaatg gatgctcccc gttaccagca tggtattgct gtcattggaa actttcttta     1620

tgtagttggt ggtcagagta attatgatac aaaaggaaaa actgctgttg atacagtttt     1680

cagatttgat cctcggtata ataaatggat gcaggttgca tcattaaatg aaaagcgcac     1740

attctttcac ttgagtgccc tcaaaggaca tttgtatgca gttggtgggc gcagtgcagc     1800

tggtgaactg gccacagtag aatgttacaa cccaagaatg aatgagtgga gctatgttgc     1860

aaaaatgagt gaaccccact atggtcatgc tggaacagta tatggaggct taatgtatat     1920

ttcaggagga attacccatg acactttcca aaatgagctc atgtgttttg acccagatac     1980

agataaatgg atgcaaaagg ctccaatgac tacagtcaga ggtctgcatt gcatgtgtac     2040

agttggagat aagctctatg tcattggtgg caatcacttc agaggaacaa gtgattatga     2100

tgatgttcta agctgtgaat actattcacc aacccttgac cagtggaccc caattgccgc     2160

catgttaaga ggccaaagtg atgttggagt tgccgtcttt gaaaataaaa tctatgttgt     2220

tggtggatat tcttggaata atcgttgtat ggtagaaatt gtccagaaat atgacccaga     2280

aaaagatgag tggcataaag tttttgatct tccagagtca cttggtggca ttcgagcctg     2340

tacactcaca gtttttccac ctgaagaaaa ccctgggtca ccttctagag aatcacctct     2400

ttcagcacct tcagatcatt cttaggtcta aggtgtaaca cctttgcagt acgtcatggg     2460

tgatctaata cttccccttc agttgtatct tcttacagtg attggtacag ttattagata     2520

taaaggtaac tgatgttatt cgtcttgtat ggcttttagt atgtttatca agtggctaac     2580

aaatgcattc tgaaaatgta tttaacatag ctgttttaac aaatgaaaaa aagacgtaga     2640

aaaatgttta gatgtctttt tgtgatgtta tataaaattg tagatgactg tggtaaatgt     2700

gtaattatgt ccattatgct tcaaagttga gttttcatct ttgactccaa aatgtcagag     2760

ggaggccgct ctaaactaaa aataacgaaa ggttgccaag tattaatact agttacctcc     2820

ctcttttcgt agtttttgtc atgtctgtca acttactcga ttgtgtggtt gcattcagaa     2880

tatttgaagt ttcttacgta gacagaaata ataaaaatat taactaggaa aaaacagtat     2940

agcaccaagc cagtatttgg tatctctctc tagagcgagc aagagaggga gagaggagga     3000

aaaaatacac ataatacaaa catacatgca tgcacacata catacatatg tatacacaca     3060

cataatttga aaactgattg gcacttcaac gatgctgaaa ttgtttttaa attgaagttt     3120

ctttcttcca caaagcagcc gtttctattc aaatggaaat tcagtaccag agaataaatg     3180

tctatgtagt catactgaat ttagatagat aagggctaca gcatactaaa tcgacaacca     3240

aatttgtcat gtgactaaac cgttacttca gatgaagctt acattactgt tttctgcttg     3300

tgtattttct gtagagtact tttacacaga ttggtaaagt tcaggtttca gagaactgct     3360

tttgtgcaga aaatttaggt tcttttttcc acctttttgg tcagtaaaac ttaatgaaaa     3420

aagcaaagaa aaaaatattc tgaacaaagc tatagggttt taagttcagc ctcccaactt     3480

agtcatccta acatgattat tttgtgattt ggggtgcttg ccctggtgct gttccagtcc     3540

atgtgcatcc tgagctgtgt gatctgcctc gaggctatga tctgagcaag caggagataa     3600

cattttcttc tgcatcaagt gaggaaaaat gtgcttttgg ccatgtctca aagacaggac     3660

caacttcaga ttcccaaaga agccagctac agagcctctg gaacactatg gtcttacaag     3720

cagtactaaa atcaaccctc agcctcttca atgccaaagg tatccctatt ggttgagaac     3780

cacatggtaa tttttaatgg gacttttatc agcaaatgga gttacaggaa ttctctgtaa     3840

tgagtgattc tgaagaggta ctttcctgga ataattgtct acctgaagaa aaaaaattta     3900

tatatacatt gtgtgtgtgt gtaatacaca cacacaaccc cctatacctg gaagattgtc     3960

agcatgtaaa tcaggaacaa ctttctcctt attgacaatc ccataataaa actcaggaac     4020

caaggcaaaa tgaattggct tctaggggtc tgaaccttac tgcccataca agtgttgatt     4080

cattttaatg ctgtttatga tttctgcatt ggcagaaatt ttcatacttt ctatgttttt     4140

ttaattactc agttttttat tactaaaaat agcacatttg agtacatttg aaaagtagaa     4200

aaattagaaa ttattaactt tattgaataa gcaagaagtg catcctaatc ctttgattat     4260

taatgaggtt gaatatttgt gtgctatcgg tagctgtgtt tctttgatca gatgttcctg     4320

tccttttgcc cttctgttat ctgttggagt tgctttgttt ttcgtatcaa gttataggat     4380

ctctttatat aataaatgta atttaacttg ca                                   4412


<210>  1674
<211>  4412
<212>  DNA
<213>  homo sapiens

<400>  1674
agccgctaag gccgctccca ccccgtggta tcctgggact aggcttttcc ggaaggagcg       60

gctcggtgtt ggggctaggc cggtattcta ggcccaagcc caggcccagg cctgtgttcc      120

cggcccttgc tcaaagacag gccggtggcc gctgcgacac tctaggtaca gcggagggcg      180

cagcgggccg ttcgctgagg tgtccggacc cgccgccgag cgggccgtgg agccacagta      240

cgtggcggcg cctcttcctt gcccgaagcg gaactgctga aggagcggca gcgcaggccg      300

gacgaggtga accaggtcat ttaaccgcct tcaggtgatg aatcatctgt ctaataatca      360

gatttgaggt ccacagccct ttgtggtcct gctacagggt gattttcagt ggatgactga      420

ctggcgtggc ccgaggggtg ccgcagtgac tgccttccct tgataaggaa acgagctttc      480

tgttctttct ggacacctcg ttacctgtaa aacattccgg ttataacttc tttatccggc      540

ttgcatctct gtgcaagagg aaagctttca catgaaagtg tcccttggta acggcgaaat      600

gggcgtctct gcccatttgc agccttgtaa ggcaggaacc acacgctttt ttaccagcaa      660

tactcacagt tcggtggtat tgcaaggctt tgatcagctt agaatagaag gattgctttg      720

tgatgtgacc ctggtaccag gtgatggaga tgaaatcttc cctgttcaca gagctatgat      780

ggcgtctgct agtgattatt tcaaagccat gttcacaggt ggaatgaaag aacaagattt      840

gatgtgcatt aagcttcatg gggtgaacaa ggttggtctg aagaaaatca ttgattttat      900

ttatactgca aaactttctc ttaatatgga caatcttcag gacacacttg aagctgctag      960

ctttttacaa atattacccg ttttggattt ctgtaaagta tttcttatat caggagtctc     1020

tttggataac tgtgttgagg ttggacgaat tgctaacacc tacaatctta tagaagtgga     1080

taaatatgtt aataatttca tcctgaagaa ctttcctgct ttattgagta ctggggagtt     1140

tctaaaactc ccttttgaac gacttgcatt tgtgctttcc agtaatagtc ttaagcactg     1200

taccgaactt gaactcttta aggcagcctg tcgctggcta aggttggaag accctcggat     1260

ggattatgct gcaaagttaa tgaagaatat tcgatttcca ctgatgacac cacaggatct     1320

catcaattac gtgcagacag tagatttcat gagaacagac aatacctgcg tgaatttgct     1380

tttggaagct agcaattacc aaatgatgcc atatatgcag ccagtgatgc agtcagatag     1440

aactgccatt cgatctgact ccactcactt ggttacatta ggaggagttt tgaggcagca     1500

gctggttgtc agtaaagaat tacggatgta tgatgaaagg gcacaagaat ggagatcttt     1560

agccccaatg gatgctcccc gttaccagca tggtattgct gtcattggaa actttcttta     1620

tgtagttggt ggtcagagta attatgatac aaaaggaaaa actgctgttg atacagtttt     1680

cagatttgat cctcggtata ataaatggat gcaggttgca tcattaaatg aaaagcgcac     1740

attctttcac ttgagtgccc tcaaaggaca tttgtatgca gttggtgggc gcagtgcagc     1800

tggtgaactg gccacagtag aatgttacaa cccaagaatg aatgagtgga gctatgttgc     1860

aaaaatgagt gaaccccact atggtcatgc tggaacagta tatggaggct taatgtatat     1920

ttcaggagga attacccatg acactttcca aaatgagctc atgtgttttg acccagatac     1980

agataaatgg atgcaaaagg ctccaatgac tacagtcaga ggtctgcatt gcatgtgtac     2040

agttggagat aagctctatg tcattggtgg caatcacttc agaggaacaa gtgattatga     2100

tgatgttcta agctgtgaat actattcacc aacccttgac cagtggaccc caattgccgc     2160

catgttaaga ggccaaagtg atgttggagt tgccgtcttt gaaaataaaa tctatgttgt     2220

tggtggatat tcttggaata atcgttgtat ggtagaaatt gtccagaaat atgacccaga     2280

aaaagatgag tggcataaag tttttgatct tccagagtca cttggtggca ttcgagcctg     2340

tacactcaca gtttttccac ctgaagaaaa ccctgggtca ccttctagag aatcacctct     2400

ttcagcacct tcagatcatt cttaggtcta aggtgtaaca cctttgcagt acgtcatggg     2460

tgatctaata cttccccttc agttgtatct tcttacagtg attggtacag ttattagata     2520

taaaggtaac tgatgttatt cgtcttgtat ggcttttagt atgtttatca agtggctaac     2580

aaatgcattc tgaaaatgta tttaacatag ctgttttaac aaatgaaaaa aagacgtaga     2640

aaaatgttta gatgtctttt tgtgatgtta tataaaattg tagatgactg tggtaaatgt     2700

gtaattatgt ccattatgct tcaaagttga gttttcatct ttgactccaa aatgtcagag     2760

ggaggccgct ctaaactaaa aataacgaaa ggttgccaag tattaatact agttacctcc     2820

ctcttttcgt agtttttgtc atgtctgtca acttactcga ttgtgtggtt gcattcagaa     2880

tatttgaagt ttcttacgta gacagaaata ataaaaatat taactaggaa aaaacagtat     2940

agcaccaagc cagtatttgg tatctctctc tagagcgagc aagagaggga gagaggagga     3000

aaaaatacac ataatacaaa catacatgca tgcacacata catacatatg tatacacaca     3060

cataatttga aaactgattg gcacttcaac gatgctgaaa ttgtttttaa attgaagttt     3120

ctttcttcca caaagcagcc gtttctattc aaatggaaat tcagtaccag agaataaatg     3180

tctatgtagt catactgaat ttagatagat aagggctaca gcatactaaa tcgacaacca     3240

aatttgtcat gtgactaaac cgttacttca gatgaagctt acattactgt tttctgcttg     3300

tgtattttct gtagagtact tttacacaga ttggtaaagt tcaggtttca gagaactgct     3360

tttgtgcaga aaatttaggt tcttttttcc acctttttgg tcagtaaaac ttaatgaaaa     3420

aagcaaagaa aaaaatattc tgaacaaagc tatagggttt taagttcagc ctcccaactt     3480

agtcatccta acatgattat tttgtgattt ggggtgcttg ccctggtgct gttccagtcc     3540

atgtgcatcc tgagctgtgt gatctgcctc gaggctatga tctgagcaag caggagataa     3600

cattttcttc tgcatcaagt gaggaaaaat gtgcttttgg ccatgtctca aagacaggac     3660

caacttcaga ttcccaaaga agccagctac agagcctctg gaacactatg gtcttacaag     3720

cagtactaaa atcaaccctc agcctcttca atgccaaagg tatccctatt ggttgagaac     3780

cacatggtaa tttttaatgg gacttttatc agcaaatgga gttacaggaa ttctctgtaa     3840

tgagtgattc tgaagaggta ctttcctgga ataattgtct acctgaagaa aaaaaattta     3900

tatatacatt gtgtgtgtgt gtaatacaca cacacaaccc cctatacctg gaagattgtc     3960

agcatgtaaa tcaggaacaa ctttctcctt attgacaatc ccataataaa actcaggaac     4020

caaggcaaaa tgaattggct tctaggggtc tgaaccttac tgcccataca agtgttgatt     4080

cattttaatg ctgtttatga tttctgcatt ggcagaaatt ttcatacttt ctatgttttt     4140

ttaattactc agttttttat tactaaaaat agcacatttg agtacatttg aaaagtagaa     4200

aaattagaaa ttattaactt tattgaataa gcaagaagtg catcctaatc ctttgattat     4260

taatgaggtt gaatatttgt gtgctatcgg tagctgtgtt tctttgatca gatgttcctg     4320

tccttttgcc cttctgttat ctgttggagt tgctttgttt ttcgtatcaa gttataggat     4380

ctctttatat aataaatgta atttaacttg ca                                   4412


<210>  1675
<211>  1213
<212>  DNA
<213>  homo sapiens

<400>  1675
aggagctgac gtgaaccgaa gtccttatat tcccgggctt ctttctcctc tgggtaccag       60

ctccttactg ccctgcagac aagcgtgccg tgcgtgcttg tggccaaggg aaggaagagc      120

tggttgatcc acagatagct ccttcctccc cgccccttcc tttttgtttg gaggtcccag      180

gatctgtgtt cacagacatc tgggggaaga aaaggagcag gaaactaccc cgcacagagt      240

taagcaggaa acaacaacaa catcatgcaa aaaccctgca aagaaaacga aggaaagcca      300

aagtgcagcg tgccaaagag ggaggaaaaa cgcccgtatg gagaatttga acgccagcaa      360

acagaaggga attttagaca gaggctgctt cagtctctcg aagaatttaa agaggacata      420

gactataggc attttaaaga tgaagaaatg acaagggagg gagatgagat ggaaaggtgt      480

ttggaagaga taaggggtct gagaaagaaa tttagggctc tgcattctaa ccataggcat      540

tctcgggacc gtccttatcc catttaatta atttctctga caattcaatt attttctgtt      600

attaatgttg ccactgcttt ctgtttgtct gcactttctt gataaatatt tgctatcgtt      660

ttactccagt cattcgatgt tgctgagatt tacatatgac tcttgtcaac atctcatctt      720

ttgacccaat cttattcatt taataagagg tctcattcat ttgcatggaa aaatgctcat      780

tgtatattgc aaagtgaaaa taacgagttg caaaacagtg tatacatata tgtgtgtata      840

tatgtacact ttatttgtac atttctatgt gacataatgc aaaggaaagt gtctgatttt      900

attatacacc aaaggttaac agtgaatctc tgtgtgatct cttttttttt ctttttgcct      960

atctgcatct tctcacttgc caaaaaatga atatatgttt atgtgtgtat attacttgtg     1020

tcacaaaaaa ccctaaagta gacagtaaaa gaacttgtca atcgcctttg gaaggcaatg     1080

aaacacttaa taaactctca ataacagaag cgtaaaaatg aaatgtaaac ctccaattac     1140

ctctggatct cttagccaga gtaataaact ggtaattatt acaggtaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaa                                                        1213


<210>  1676
<211>  1213
<212>  DNA
<213>  homo sapiens

<400>  1676
aggagctgac gtgaaccgaa gtccttatat tcccgggctt ctttctcctc tgggtaccag       60

ctccttactg ccctgcagac aagcgtgccg tgcgtgcttg tggccaaggg aaggaagagc      120

tggttgatcc acagatagct ccttcctccc cgccccttcc tttttgtttg gaggtcccag      180

gatctgtgtt cacagacatc tgggggaaga aaaggagcag gaaactaccc cgcacagagt      240

taagcaggaa acaacaacaa catcatgcaa aaaccctgca aagaaaacga aggaaagcca      300

aagtgcagcg tgccaaagag ggaggaaaaa cgcccgtatg gagaatttga acgccagcaa      360

acagaaggga attttagaca gaggctgctt cagtctctcg aagaatttaa agaggacata      420

gactataggc attttaaaga tgaagaaatg acaagggagg gagatgagat ggaaaggtgt      480

ttggaagaga taaggggtct gagaaagaaa tttagggctc tgcattctaa ccataggcat      540

tctcgggacc gtccttatcc catttaatta atttctctga caattcaatt attttctgtt      600

attaatgttg ccactgcttt ctgtttgtct gcactttctt gataaatatt tgctatcgtt      660

ttactccagt cattcgatgt tgctgagatt tacatatgac tcttgtcaac atctcatctt      720

ttgacccaat cttattcatt taataagagg tctcattcat ttgcatggaa aaatgctcat      780

tgtatattgc aaagtgaaaa taacgagttg caaaacagtg tatacatata tgtgtgtata      840

tatgtacact ttatttgtac atttctatgt gacataatgc aaaggaaagt gtctgatttt      900

attatacacc aaaggttaac agtgaatctc tgtgtgatct cttttttttt ctttttgcct      960

atctgcatct tctcacttgc caaaaaatga atatatgttt atgtgtgtat attacttgtg     1020

tcacaaaaaa ccctaaagta gacagtaaaa gaacttgtca atcgcctttg gaaggcaatg     1080

aaacacttaa taaactctca ataacagaag cgtaaaaatg aaatgtaaac ctccaattac     1140

ctctggatct cttagccaga gtaataaact ggtaattatt acaggtaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaa                                                        1213


<210>  1677
<211>  4734
<212>  DNA
<213>  homo sapiens

<400>  1677
tccggaggcg agccgagcgc ggtggtgagg ccgcctcagc gaaaaaaatg tccgcctgaa       60

gagacccaca agttctattc ggggggaccg acagcccgcc ccgggaggaa ggggcggcca      120

ggcccgaaag ccgcctcccc ctcccagacc cgagagctcg tgcggggcaa agtgaaccga      180

gccgctgggc ggtgcaaggg gaagcccaag cccgttctcc cggccaaagt gaactttaat      240

cggggtggtt ggatgcggag acggggcggc aggacctgct agaagtggcc gaagatgaat      300

ccccagcaac aacgcatggc cgctataggg accgacaagg agctgagcga cctactggac      360

ttcagtgcga tgttttcccc acctgttaat agtgggaaaa ctagaccaac tacactggga      420

agcagtcaat tcagtggatc aggtattgat gaaagaggag gtacaacatc ttggggaaca      480

agtggtcaac caagtccttc ctatgattca tctagaggtt ttacagacag ccctcattac      540

agtgatcact tgaatgacag tcgattagga gcccatgaag gcttgtcccc aacacctttc      600

atgaactcaa atctgatggg aaaaacatca gagagaggct cattttccct gtacagcaga      660

gatactggat taccaggctg tcaatctagt ctcctgagac aagatctggg gcttgggagc      720

ccagcacagc tatcttcttc aggaaaacct gggacagcat actattcatt ctctgctaca      780

agttccagga ggagaccact ccatgactct gcagcgcttg atcccttgca agcaaaaaaa      840

gtcagaaagg tgcctcctgg tttgccttct tctgtatatg caccatcccc aaattcagat      900

gatttcaacc gtgaatctcc tagttatcca tctcctaagc caccaaccag tatgttcgct      960

agcactttct ttatgcaaga tgggacccac aattcttctg acctttggag ttcatcaaat     1020

gggatgagcc agcctggttt tggtggaatt ctggggacct ccacttccca catgtctcaa     1080

tccagtagtt atggcaacct tcattcacat gaccgcttga gttatcctcc acactcagtt     1140

tcaccaacag acataaacac gagtcttcca ccaatgtcca gctttcatcg cggcagtacc     1200

agcagttcac cttacgttgc tgcctcacac actcctccca tcaatggatc agacagcatt     1260

ctaggaacca gagggaatgc tgctggaagc tcacagacag gtgatgcact tggaaaggct     1320

ttggcatcta tttattctcc tgaccatacc agcagtagtt ttccgtcaaa tccatcaaca     1380

ccagttggat caccttcacc tctcacaggt accagtcagt ggccaagacc tggagggcaa     1440

gcaccttcat ccccaagcta tgaaaactca ctccactccc tgcagtctcg aatggaggat     1500

cgtttagaca gactggatga tgcaatccat gtgctgcgga accatgctgt gggaccttcc     1560

accagtttgc ctgctggtca cagtgatata catagtttat tgggaccatc ccataatgca     1620

ccaattggaa gcctcaattc aaactatgga ggatcaagcc ttgttgcaag cagtcgatca     1680

gcttcaatgg ttggaactca tcgggaagac tctgtcagtc tcaatggcaa tcattcagtc     1740

ctgtctagta cagtcactac ttcaagcaca gacctgaacc ataaaacaca agaaaattat     1800

agaggtggct tgcaaagtca gtctggaact gttgttacaa cagaaatcaa gactgaaaac     1860

aaagaaaagg atgaaaacct tcatgaacct ccttcatcag atgacatgaa gtcagatgat     1920

gaatcctccc aaaaagatat caaggtttca tctagaggca gaacaagcag tactaatgaa     1980

gatgaggatt tgaaccctga acagaagata gaaagggaga aggagaggcg gatggctaac     2040

aatgccagag aacgcttacg cgtgcgggat attaatgaag cattcaaaga gcttggccga     2100

atgtgtcagc ttcacttgaa gagtgaaaaa ccccaaacaa aactccttat tcttcatcaa     2160

gccgtggcag tcatccttag tctagaacag caagtcagag agaggaacct taaccccaaa     2220

gcagcctgcc ttaagagaag ggaagaagaa aaagtttctg ccgtatcggc agagccgcca     2280

accacactgc caggaaccca tcctgggctt agtgaaacta ccaaccctat gggtcatatg     2340

taaacatcag ccagttccag agttatcagt aggctagata gaaggtgacc tctcctcata     2400

aggacttgga caactcagat tatctgaaga cacaaacctg acaggaggga gaagaaaaaa     2460

caaaacactt gaaccaagaa actcaaatgt aatcctacga tcaaagcaac tggtcaacac     2520

ttccatcaga agtgaagata ggaagctcat cagatagaac atcagcccat gagatgtttg     2580

caacaaatct tttgttgcaa gcagtgtgtc gcttctgcac aatcagagac tgtctcgatc     2640

tctccactca ccgtggaagt tgccttgtgc ctaaactgaa ttgacaaatg cattgtaact     2700

acaaatttta tttattgtta tgaaactgta aggtctacat ataaagggaa aaagttaatg     2760

tggaaagctg atctacactc agctgatgcc agcatacatt aaagcggttc acgtgcagag     2820

aacaaagcag tgacaaccat tggcccttag cattcccggc atacctatta gtgtcttaaa     2880

aaggaaggga aaagtctttt gttgccctct cctatcctct tgccatatga atagcgtttt     2940

ccatgaaata ggaaaatatt acttggtata gcatttctct tgctctcatt ttttgattta     3000

tttttatttt ctctttgtgg gtgttatatt tgatctctaa atctgaacag tttatggtca     3060

cagtccagcc tcctccgtgc agccctgtgt gctttgcaca tttaccttac agtggtaagc     3120

agagaccatc tgtgaccata gcctagctag cattttaaaa ggggaaattt tgttctctag     3180

gttttccccc aaataaacat tgctttattt ctaataataa ccaagacttt tcaagcttct     3240

agatctcata ggaaagcttg taatagcaaa attgtaaatt acaagggaag aatctacttt     3300

ttagaaatcg ctttgttttc caagcagtaa gtactacata cagtacttgt aaagtgttag     3360

ctgtaagtaa gcacaaaata catttaaaat acaaagacga ttttttcagg ctgtgattat     3420

ggtgaacata acaaaaccca gtagtcacca aggcaggtag tgtgataaat gaacacacca     3480

ctctgaggct aattacctaa tggaatacaa gagcaatggt cacccgtatt tccttatcct     3540

agcctttatt tctctgtcat ttggatggct ggtcaatggg gaagaattga gtgggtgatt     3600

taatcaactg caaaccatct gcccctgtcc caaaatgatg agccagatta gcattaaacc     3660

agtacttgtc agtccatctt aatactgttc attaaggcac tctctgtctc taatccttag     3720

gagttgtttt aaaagacata atcactttga acttccatga aacctgtctt ccaccacaac     3780

aaccctggga gagaaaaaca tgctaaagga ggtatcttgg cttaataatt ccttatagcc     3840

aatatcaaca gtggcaatca gcacacagag gaaaggaccc aaatcactat gtagcttaaa     3900

gatttctgtt aatttgaaag aacaaaaaca agacagaact tctggtactc taatcaggat     3960

gattcctaac aagtcagtca tttgtgaact tagtggactt tttggttact ttaatttgca     4020

tatattctcc agttacatcg gactctatct gtggccttgt tcttcatttc agtgttaatc     4080

agctaaacag aagttgttgc ttatgatgtg tgagtgaaca tatgccactg cctggccttt     4140

ttttcttcag agcttgttgt ctttttcgct atattagact ttgcagtatg cccagaagct     4200

ttccttcata aaatagaaag aaaaaaacat ttggcttatt tttcactgta gctagtcttt     4260

tatacaataa tcttgtaaga aaatttcttg aattctaaat attactcttt ctagattttt     4320

gaaatcaaaa agttttcagt aaaaagtttc ttactttatt ttattatatt aggtagtaaa     4380

aaatgtaggg ttatttacca taacctgttc attaatatca gaaatttaca atagcatttt     4440

aagaccatag taggattcta gcataccgtg tagtacctat ggagtattgt aagagctaat     4500

tgttggagat gaattgcttc tcatcttgtt ctccagtttc cattgttggt ttattgcaga     4560

tttgtatcct gtgtcaaatt caaggtatta ttgataaacc ttttcaacca gcagcaagaa     4620

gttcaaattt ttttctgtca ctgtaacaga aaacacaata tgtatataac atttatgtag     4680

caataaatgt gccatctttt ttttaacaca gtaaaaaaaa aaaaaaaaaa aaaa           4734


<210>  1678
<211>  4796
<212>  DNA
<213>  homo sapiens

<400>  1678
tccggaggcg agccgagcgc ggtggtgagg ccgcctcagc gaaaaaaatg tccgcctgaa       60

gagacccaca agttctattc ggggggaccg acagcccgcc ccgggaggaa ggggcggcca      120

ggcccgaaag ccgcctcccc ctcccagacc cgagagctcg tgcggggcaa agtgaaccga      180

gccgctgggc ggtgcaaggg gaagcccaag cccgttctcc cggccaaagt gaactttaat      240

cggggtggtt ggatgcggag acggggcggc agaagtggcc gaagatgaat ccccagcaac      300

aacgcatggc cgctataggg accgacaagg agctgagcga cctactggac ttcagtgcga      360

tgttttcccc acctgttaat agtgggaaaa ctagaccaac tacactggga agcagtcaat      420

tcagtggatc aggtattgat gaaagaggag gtacaacatc ttggggaaca agtggtcaac      480

caagtccttc ctatgattca tctagaggtt ttacagacag ccctcattac agtgatcact      540

tgaatgacag tcgattagga gcccatgaag gcttgtcccc aacacctttc atgaactcaa      600

atctgatggg aaaaacatca gagagaggct cattttccct gtacagcaga gatactggat      660

taccaggctg tcaatctagt ctcctgagac aagatctggg gcttgggagc ccagcacagc      720

tatcttcttc aggaaaacct gggacagcat actattcatt ctctgctaca agttccagga      780

ggagaccact ccatgactct gcagcgcttg atcccttgca agcaaaaaaa gtcagaaagg      840

tgcctcctgg tttgccttct tctgtatatg caccatcccc aaattcagat gatttcaacc      900

gtgaatctcc tagttatcca tctcctaagc caccaaccag tatgttcgct agcactttct      960

ttatgcaaga tgggacccac aattcttctg acctttggag ttcatcaaat gggatgagcc     1020

agcctggttt tggtggaatt ctggggacct ccacttccca catgtctcaa tccagtagtt     1080

atggcaacct tcattcacat gaccgcttga gttatcctcc acactcagtt tcaccaacag     1140

acataaacac gagtcttcca ccaatgtcca gctttcatcg cggcagtacc agcagttcac     1200

cttacgttgc tgcctcacac actcctccca tcaatggatc agacagcatt ctaggaacca     1260

gagggaatgc tgctggaagc tcacagacag gtgatgcact tggaaaggct ttggcatcta     1320

tttattctcc tgaccatacc agcagtagtt ttccgtcaaa tccatcaaca ccagttggat     1380

caccttcacc tctcacaggt accagtcagt ggccaagacc tggagggcaa gcaccttcat     1440

ccccaagcta tgaaaactca ctccactccc tgaaaaatcg agttgagcag caacttcacg     1500

agcatttgca agatgcaatg tccttcttaa aggatgtctg tgagcagtct cgaatggagg     1560

atcgtttaga cagactggat gatgcaatcc atgtgctgcg gaaccatgct gtgggacctt     1620

ccaccagttt gcctgctggt cacagtgata tacatagttt attgggacca tcccataatg     1680

caccaattgg aagcctcaat tcaaactatg gaggatcaag ccttgttgca agcagtcgat     1740

cagcttcaat ggttggaact catcgggaag actctgtcag tctcaatggc aatcattcag     1800

tcctgtctag tacagtcact acttcaagca cagacctgaa ccataaaaca caagaaaatt     1860

atagaggtgg cttgcaaagt cagtctggaa ctgttgttac aacagaaatc aagactgaaa     1920

acaaagaaaa ggatgaaaac cttcatgaac ctccttcatc agatgacatg aagtcagatg     1980

atgaatcctc ccaaaaagat atcaaggttt catctagagg cagaacaagc agtactaatg     2040

aagatgagga tttgaaccct gaacagaaga tagaaaggga gaaggagagg cggatggcta     2100

acaatgccag agaacgctta cgcgtgcggg atattaatga agcattcaaa gagcttggcc     2160

gaatgtgtca gcttcacttg aagagtgaaa aaccccaaac aaaactcctt attcttcatc     2220

aagccgtggc agtcatcctt agtctagaac agcaagtcag agagaggaac cttaacccca     2280

aagcagcctg ccttaagaga agggaagaag aaaaagtttc tgccgtatcg gcagagccgc     2340

caaccacact gccaggaacc catcctgggc ttagtgaaac taccaaccct atgggtcata     2400

tgtaaacatc agccagttcc agagttatca gtaggctaga tagaaggtga cctctcctca     2460

taaggacttg gacaactcag attatctgaa gacacaaacc tgacaggagg gagaagaaaa     2520

aacaaaacac ttgaaccaag aaactcaaat gtaatcctac gatcaaagca actggtcaac     2580

acttccatca gaagtgaaga taggaagctc atcagataga acatcagccc atgagatgtt     2640

tgcaacaaat cttttgttgc aagcagtgtg tcgcttctgc acaatcagag actgtctcga     2700

tctctccact caccgtggaa gttgccttgt gcctaaactg aattgacaaa tgcattgtaa     2760

ctacaaattt tatttattgt tatgaaactg taaggtctac atataaaggg aaaaagttaa     2820

tgtggaaagc tgatctacac tcagctgatg ccagcataca ttaaagcggt tcacgtgcag     2880

agaacaaagc agtgacaacc attggccctt agcattcccg gcatacctat tagtgtctta     2940

aaaaggaagg gaaaagtctt ttgttgccct ctcctatcct cttgccatat gaatagcgtt     3000

ttccatgaaa taggaaaata ttacttggta tagcatttct cttgctctca ttttttgatt     3060

tatttttatt ttctctttgt gggtgttata tttgatctct aaatctgaac agtttatggt     3120

cacagtccag cctcctccgt gcagccctgt gtgctttgca catttacctt acagtggtaa     3180

gcagagacca tctgtgacca tagcctagct agcattttaa aaggggaaat tttgttctct     3240

aggttttccc ccaaataaac attgctttat ttctaataat aaccaagact tttcaagctt     3300

ctagatctca taggaaagct tgtaatagca aaattgtaaa ttacaaggga agaatctact     3360

ttttagaaat cgctttgttt tccaagcagt aagtactaca tacagtactt gtaaagtgtt     3420

agctgtaagt aagcacaaaa tacatttaaa atacaaagac gattttttca ggctgtgatt     3480

atggtgaaca taacaaaacc cagtagtcac caaggcaggt agtgtgataa atgaacacac     3540

cactctgagg ctaattacct aatggaatac aagagcaatg gtcacccgta tttccttatc     3600

ctagccttta tttctctgtc atttggatgg ctggtcaatg gggaagaatt gagtgggtga     3660

tttaatcaac tgcaaaccat ctgcccctgt cccaaaatga tgagccagat tagcattaaa     3720

ccagtacttg tcagtccatc ttaatactgt tcattaaggc actctctgtc tctaatcctt     3780

aggagttgtt ttaaaagaca taatcacttt gaacttccat gaaacctgtc ttccaccaca     3840

acaaccctgg gagagaaaaa catgctaaag gaggtatctt ggcttaataa ttccttatag     3900

ccaatatcaa cagtggcaat cagcacacag aggaaaggac ccaaatcact atgtagctta     3960

aagatttctg ttaatttgaa agaacaaaaa caagacagaa cttctggtac tctaatcagg     4020

atgattccta acaagtcagt catttgtgaa cttagtggac tttttggtta ctttaatttg     4080

catatattct ccagttacat cggactctat ctgtggcctt gttcttcatt tcagtgttaa     4140

tcagctaaac agaagttgtt gcttatgatg tgtgagtgaa catatgccac tgcctggcct     4200

ttttttcttc agagcttgtt gtctttttcg ctatattaga ctttgcagta tgcccagaag     4260

ctttccttca taaaatagaa agaaaaaaac atttggctta tttttcactg tagctagtct     4320

tttatacaat aatcttgtaa gaaaatttct tgaattctaa atattactct ttctagattt     4380

ttgaaatcaa aaagttttca gtaaaaagtt tcttacttta ttttattata ttaggtagta     4440

aaaaatgtag ggttatttac cataacctgt tcattaatat cagaaattta caatagcatt     4500

ttaagaccat agtaggattc tagcataccg tgtagtacct atggagtatt gtaagagcta     4560

attgttggag atgaattgct tctcatcttg ttctccagtt tccattgttg gtttattgca     4620

gatttgtatc ctgtgtcaaa ttcaaggtat tattgataaa ccttttcaac cagcagcaag     4680

aagttcaaat ttttttctgt cactgtaaca gaaaacacaa tatgtatata acatttatgt     4740

agcaataaat gtgccatctt ttttttaaca cagtaaaaaa aaaaaaaaaa aaaaaa         4796


<210>  1679
<211>  4806
<212>  DNA
<213>  homo sapiens

<400>  1679
tccggaggcg agccgagcgc ggtggtgagg ccgcctcagc gaaaaaaatg tccgcctgaa       60

gagacccaca agttctattc ggggggaccg acagcccgcc ccgggaggaa ggggcggcca      120

ggcccgaaag ccgcctcccc ctcccagacc cgagagctcg tgcggggcaa agtgaaccga      180

gccgctgggc ggtgcaaggg gaagcccaag cccgttctcc cggccaaagt gaactttaat      240

cggggtggtt ggatgcggag acggggcggc aggacctgct agaagtggcc gaagatgaat      300

ccccagcaac aacgcatggc cgctataggg accgacaagg agctgagcga cctactggac      360

ttcagtgcga tgttttcccc acctgttaat agtgggaaaa ctagaccaac tacactggga      420

agcagtcaat tcagtggatc aggtattgat gaaagaggag gtacaacatc ttggggaaca      480

agtggtcaac caagtccttc ctatgattca tctagaggtt ttacagacag ccctcattac      540

agtgatcact tgaatgacag tcgattagga gcccatgaag gcttgtcccc aacacctttc      600

atgaactcaa atctgatggg aaaaacatca gagagaggct cattttccct gtacagcaga      660

gatactggat taccaggctg tcaatctagt ctcctgagac aagatctggg gcttgggagc      720

ccagcacagc tatcttcttc aggaaaacct gggacagcat actattcatt ctctgctaca      780

agttccagga ggagaccact ccatgactct gcagcgcttg atcccttgca agcaaaaaaa      840

gtcagaaagg tgcctcctgg tttgccttct tctgtatatg caccatcccc aaattcagat      900

gatttcaacc gtgaatctcc tagttatcca tctcctaagc caccaaccag tatgttcgct      960

agcactttct ttatgcaaga tgggacccac aattcttctg acctttggag ttcatcaaat     1020

gggatgagcc agcctggttt tggtggaatt ctggggacct ccacttccca catgtctcaa     1080

tccagtagtt atggcaacct tcattcacat gaccgcttga gttatcctcc acactcagtt     1140

tcaccaacag acataaacac gagtcttcca ccaatgtcca gctttcatcg cggcagtacc     1200

agcagttcac cttacgttgc tgcctcacac actcctccca tcaatggatc agacagcatt     1260

ctaggaacca gagggaatgc tgctggaagc tcacagacag gtgatgcact tggaaaggct     1320

ttggcatcta tttattctcc tgaccatacc agcagtagtt ttccgtcaaa tccatcaaca     1380

ccagttggat caccttcacc tctcacaggt accagtcagt ggccaagacc tggagggcaa     1440

gcaccttcat ccccaagcta tgaaaactca ctccactccc tgaaaaatcg agttgagcag     1500

caacttcacg agcatttgca agatgcaatg tccttcttaa aggatgtctg tgagcagtct     1560

cgaatggagg atcgtttaga cagactggat gatgcaatcc atgtgctgcg gaaccatgct     1620

gtgggacctt ccaccagttt gcctgctggt cacagtgata tacatagttt attgggacca     1680

tcccataatg caccaattgg aagcctcaat tcaaactatg gaggatcaag ccttgttgca     1740

agcagtcgat cagcttcaat ggttggaact catcgggaag actctgtcag tctcaatggc     1800

aatcattcag tcctgtctag tacagtcact acttcaagca cagacctgaa ccataaaaca     1860

caagaaaatt atagaggtgg cttgcaaagt cagtctggaa ctgttgttac aacagaaatc     1920

aagactgaaa acaaagaaaa ggatgaaaac cttcatgaac ctccttcatc agatgacatg     1980

aagtcagatg atgaatcctc ccaaaaagat atcaaggttt catctagagg cagaacaagc     2040

agtactaatg aagatgagga tttgaaccct gaacagaaga tagaaaggga gaaggagagg     2100

cggatggcta acaatgccag agaacgctta cgcgtgcggg atattaatga agcattcaaa     2160

gagcttggcc gaatgtgtca gcttcacttg aagagtgaaa aaccccaaac aaaactcctt     2220

attcttcatc aagccgtggc agtcatcctt agtctagaac agcaagtcag agagaggaac     2280

cttaacccca aagcagcctg ccttaagaga agggaagaag aaaaagtttc tgccgtatcg     2340

gcagagccgc caaccacact gccaggaacc catcctgggc ttagtgaaac taccaaccct     2400

atgggtcata tgtaaacatc agccagttcc agagttatca gtaggctaga tagaaggtga     2460

cctctcctca taaggacttg gacaactcag attatctgaa gacacaaacc tgacaggagg     2520

gagaagaaaa aacaaaacac ttgaaccaag aaactcaaat gtaatcctac gatcaaagca     2580

actggtcaac acttccatca gaagtgaaga taggaagctc atcagataga acatcagccc     2640

atgagatgtt tgcaacaaat cttttgttgc aagcagtgtg tcgcttctgc acaatcagag     2700

actgtctcga tctctccact caccgtggaa gttgccttgt gcctaaactg aattgacaaa     2760

tgcattgtaa ctacaaattt tatttattgt tatgaaactg taaggtctac atataaaggg     2820

aaaaagttaa tgtggaaagc tgatctacac tcagctgatg ccagcataca ttaaagcggt     2880

tcacgtgcag agaacaaagc agtgacaacc attggccctt agcattcccg gcatacctat     2940

tagtgtctta aaaaggaagg gaaaagtctt ttgttgccct ctcctatcct cttgccatat     3000

gaatagcgtt ttccatgaaa taggaaaata ttacttggta tagcatttct cttgctctca     3060

ttttttgatt tatttttatt ttctctttgt gggtgttata tttgatctct aaatctgaac     3120

agtttatggt cacagtccag cctcctccgt gcagccctgt gtgctttgca catttacctt     3180

acagtggtaa gcagagacca tctgtgacca tagcctagct agcattttaa aaggggaaat     3240

tttgttctct aggttttccc ccaaataaac attgctttat ttctaataat aaccaagact     3300

tttcaagctt ctagatctca taggaaagct tgtaatagca aaattgtaaa ttacaaggga     3360

agaatctact ttttagaaat cgctttgttt tccaagcagt aagtactaca tacagtactt     3420

gtaaagtgtt agctgtaagt aagcacaaaa tacatttaaa atacaaagac gattttttca     3480

ggctgtgatt atggtgaaca taacaaaacc cagtagtcac caaggcaggt agtgtgataa     3540

atgaacacac cactctgagg ctaattacct aatggaatac aagagcaatg gtcacccgta     3600

tttccttatc ctagccttta tttctctgtc atttggatgg ctggtcaatg gggaagaatt     3660

gagtgggtga tttaatcaac tgcaaaccat ctgcccctgt cccaaaatga tgagccagat     3720

tagcattaaa ccagtacttg tcagtccatc ttaatactgt tcattaaggc actctctgtc     3780

tctaatcctt aggagttgtt ttaaaagaca taatcacttt gaacttccat gaaacctgtc     3840

ttccaccaca acaaccctgg gagagaaaaa catgctaaag gaggtatctt ggcttaataa     3900

ttccttatag ccaatatcaa cagtggcaat cagcacacag aggaaaggac ccaaatcact     3960

atgtagctta aagatttctg ttaatttgaa agaacaaaaa caagacagaa cttctggtac     4020

tctaatcagg atgattccta acaagtcagt catttgtgaa cttagtggac tttttggtta     4080

ctttaatttg catatattct ccagttacat cggactctat ctgtggcctt gttcttcatt     4140

tcagtgttaa tcagctaaac agaagttgtt gcttatgatg tgtgagtgaa catatgccac     4200

tgcctggcct ttttttcttc agagcttgtt gtctttttcg ctatattaga ctttgcagta     4260

tgcccagaag ctttccttca taaaatagaa agaaaaaaac atttggctta tttttcactg     4320

tagctagtct tttatacaat aatcttgtaa gaaaatttct tgaattctaa atattactct     4380

ttctagattt ttgaaatcaa aaagttttca gtaaaaagtt tcttacttta ttttattata     4440

ttaggtagta aaaaatgtag ggttatttac cataacctgt tcattaatat cagaaattta     4500

caatagcatt ttaagaccat agtaggattc tagcataccg tgtagtacct atggagtatt     4560

gtaagagcta attgttggag atgaattgct tctcatcttg ttctccagtt tccattgttg     4620

gtttattgca gatttgtatc ctgtgtcaaa ttcaaggtat tattgataaa ccttttcaac     4680

cagcagcaag aagttcaaat ttttttctgt cactgtaaca gaaaacacaa tatgtatata     4740

acatttatgt agcaataaat gtgccatctt ttttttaaca cagtaaaaaa aaaaaaaaaa     4800

aaaaaa                                                                4806


<210>  1680
<211>  4717
<212>  DNA
<213>  homo sapiens

<400>  1680
tccggaggcg agccgagcgc ggtggtgagg ccgcctcagc gaaaaaaatg tccgcctgaa       60

gagacccaca agttctattc ggggggaccg acagcccgcc ccgggaggaa ggggcggcca      120

ggcccgaaag ccgcctcccc ctcccagacc cgagagctcg tgcggggcaa agtgaaccga      180

gccgctgggc ggtgcaaggg gaagcccaag cccgttctcc cggccaaagt gaactttaat      240

cggggtggtt ggatgcggag acggggcggc agaagtggcc gaagatgaat ccccagcaac      300

aacgcatggc cgctataggg accgacaagg agctgagcga cctactggac ttcagtgcga      360

tgttttcccc acctgttaat agtgggaaaa ctagaccaac tacactggga agcagtcaat      420

tcagtggatc aggtattgat gaaagaggag gtacaacatc ttggggaaca agtggtcaac      480

caagtccttc ctatgattca tctagaggtt ttacagacag ccctcattac agtgatcact      540

tgaatgacag tcgattagga gcccatgaag gcttgtcccc aacacctttc atgaactcaa      600

atctgatggg aaaaacatca gagagaggct cattttccct gtacagcaga gatactggat      660

taccaggctg tcaatctagt ctcctgagac aagatctggg gcttgggagc ccagcacagc      720

tatcttcttc aggaaaacct gggacagcat actattcatt ctctgctaca agttccagga      780

ggagaccact ccatgactct gcagcgcttg atcccttgca agcaaaaaaa gtcagaaagg      840

tgcctcctgg tttgccttct tctgtatatg caccatcccc aaattcagat gatttcaacc      900

gtgaatctcc tagttatcca tctcctaagc caccaaccag tatgttcgct agcactttct      960

ttatgcaaga tgggacccac aattcttctg acctttggag ttcatcaaat gggatgagcc     1020

agcctggttt tggtggaatt ctggggacct ccacttccca catgtctcaa tccagtagtt     1080

atggcaacct tcattcacat gaccgcttga gttatcctcc acactcagtt tcaccaacag     1140

acataaacac gagtcttcca ccaatgtcca gctttcatcg cggcagtacc agcagttcac     1200

cttacgttgc tgcctcacac actcctccca tcaatggatc agacagcatt ctaggaacca     1260

gagggaatgc tgctggaagc tcacagacag gtgatgcact tggaaaggct ttggcatcta     1320

tttattctcc tgaccatacc agcagtagtt ttccgtcaaa tccatcaaca ccagttggat     1380

caccttcacc tctcacaggt accagtcagt ggccaagacc tggagggcaa gcaccttcat     1440

ccccaagcta tgaaaactca ctccactccc tgcagtctcg aatggaggat cgtttagaca     1500

gactggatga tgcaatccat gtgctgcgga accatgctgt gggaccttcc accagtttgc     1560

ctgctggtca cagtgatata catagtttat tgggaccatc ccataatgca ccaattggaa     1620

gcctcaattc aaactatgga ggatcaagcc ttgttgcaag cagtcgatca gcttcaatgg     1680

ttggaactca tcgggaagac tctgtcagtc tcaatggcaa tcattcagtc ctgtctagta     1740

cagtcactac ttcaagcaca gacctgaacc ataaaacaca agaaaattat agaggtggct     1800

tgcaaagtca gtctggaact gttgttacaa cagaaatcaa gactgaaaac aaagaaaagg     1860

atgaaaacct tcatgaacct ccttcatcag atgacatgaa gtcagatgat gaatcctccc     1920

aaaaagatat caaggtttca tctagaggca gaacaagcag tactaatgaa gatgaggatt     1980

tgaaccctga acagaagata gaaagggaga aggagaggcg gatggctaac aatgccagag     2040

aacgcttacg cgtgcgggat attaatgaag cattcaaaga gcttggccga atgtgtcagc     2100

ttcacttgaa gagtgaaaaa ccccaaacaa aactccttat tcttcatcaa gccgtggcag     2160

tcatccttag tctagaacag caagtcagag agaggaacct taaccccaaa gcagcctgcc     2220

ttaagagaag ggaagaagaa aaagtttctg ccgtatcggc agagccgcca accacactgc     2280

caggaaccca tcctgggctt agtgaaacta ccaaccctat gggtcatatg taaacatcag     2340

ccagttccag agttatcagt aggctagata gaaggtgacc tctcctcata aggacttgga     2400

caactcagat tatctgaaga cacaaacctg acaggaggga gaagaaaaaa caaaacactt     2460

gaaccaagaa actcaaatgt aatcctacga tcaaagcaac tggtcaacac ttccatcaga     2520

agtgaagata ggaagctcat cagatagaac atcagcccat gagatgtttg caacaaatct     2580

tttgttgcaa gcagtgtgtc gcttctgcac aatcagagac tgtctcgatc tctccactca     2640

ccgtggaagt tgccttgtgc ctaaactgaa ttgacaaatg cattgtaact acaaatttta     2700

tttattgtta tgaaactgta aggtctacat ataaagggaa aaagttaatg tggaaagctg     2760

atctacactc agctgatgcc agcatacatt aaagcggttc acgtgcagag aacaaagcag     2820

tgacaaccat tggcccttag cattcccggc atacctatta gtgtcttaaa aaggaaggga     2880

aaagtctttt gttgccctct cctatcctct tgccatatga atagcgtttt ccatgaaata     2940

ggaaaatatt acttggtata gcatttctct tgctctcatt ttttgattta tttttatttt     3000

ctctttgtgg gtgttatatt tgatctctaa atctgaacag tttatggtca cagtccagcc     3060

tcctccgtgc agccctgtgt gctttgcaca tttaccttac agtggtaagc agagaccatc     3120

tgtgaccata gcctagctag cattttaaaa ggggaaattt tgttctctag gttttccccc     3180

aaataaacat tgctttattt ctaataataa ccaagacttt tcaagcttct agatctcata     3240

ggaaagcttg taatagcaaa attgtaaatt acaagggaag aatctacttt ttagaaatcg     3300

ctttgttttc caagcagtaa gtactacata cagtacttgt aaagtgttag ctgtaagtaa     3360

gcacaaaata catttaaaat acaaagacga ttttttcagg ctgtgattat ggtgaacata     3420

acaaaaccca gtagtcacca aggcaggtag tgtgataaat gaacacacca ctctgaggct     3480

aattacctaa tggaatacaa gagcaatggt cacccgtatt tccttatcct agcctttatt     3540

tctctgtcat ttggatggct ggtcaatggg gaagaattga gtgggtgatt taatcaactg     3600

caaaccatct gcccctgtcc caaaatgatg agccagatta gcattaaacc agtacttgtc     3660

agtccatctt aatactgttc attaaggcac tctctgtctc taatccttag gagttgtttt     3720

aaaagacata atcactttga acttccatga aacctgtctt ccaccacaac aaccctggga     3780

gagaaaaaca tgctaaagga ggtatcttgg cttaataatt ccttatagcc aatatcaaca     3840

gtggcaatca gcacacagag gaaaggaccc aaatcactat gtagcttaaa gatttctgtt     3900

aatttgaaag aacaaaaaca agacagaact tctggtactc taatcaggat gattcctaac     3960

aagtcagtca tttgtgaact tagtggactt tttggttact ttaatttgca tatattctcc     4020

agttacatcg gactctatct gtggccttgt tcttcatttc agtgttaatc agctaaacag     4080

aagttgttgc ttatgatgtg tgagtgaaca tatgccactg cctggccttt ttttcttcag     4140

agcttgttgt ctttttcgct atattagact ttgcagtatg cccagaagct ttccttcata     4200

aaatagaaag aaaaaaacat ttggcttatt tttcactgta gctagtcttt tatacaataa     4260

tcttgtaaga aaatttcttg aattctaaat attactcttt ctagattttt gaaatcaaaa     4320

agttttcagt aaaaagtttc ttactttatt ttattatatt aggtagtaaa aaatgtaggg     4380

ttatttacca taacctgttc attaatatca gaaatttaca atagcatttt aagaccatag     4440

taggattcta gcataccgtg tagtacctat ggagtattgt aagagctaat tgttggagat     4500

gaattgcttc tcatcttgtt ctccagtttc cattgttggt ttattgcaga tttgtatcct     4560

gtgtcaaatt caaggtatta ttgataaacc ttttcaacca gcagcaagaa gttcaaattt     4620

ttttctgtca ctgtaacaga aaacacaata tgtatataac atttatgtag caataaatgt     4680

gccatctttt ttttaacaca gtaaaaaaaa aaaaaaa                              4717


<210>  1681
<211>  4698
<212>  DNA
<213>  homo sapiens

<400>  1681
cttgcgcact gagaactcac accatatgtg tcctgttcca gtgcgcgggt ctgtggagag       60

ccgggtgcga gcggcggcag cacgagggga aaagagctga gcggagacca aagtcagccg      120

ggagacagtg ggtctgtgag agaccgaata gaggggctgg ggccacgagc gccattgaca      180

agcaatgggg aagaaacaga aaaacaagag cgaagacagc accaaggatg acattgatct      240

tgatgccttg gctgcagaaa tagaaggagc tggtgctgcc aaagaacagg agcctcaaaa      300

gtcaaaaggg aaaaagaaaa aagagaaaaa aaagcaggac tttgatgaag atgatatcct      360

gaaagaactg gaagaattgt ctttggaagc tcaaggcatc aaagctgaca gagaaactgt      420

tgcagtgaag ccaacagaaa acaatgaaga ggaattcacc tcaaaagata aaaaaaagaa      480

aggacagaag ggcaaaaaac agagttttga tgataatgat agcgaagaat tggaagataa      540

agattcaaaa tcaaaaaaga ctgcaaaacc gaaagtggaa atgtactctg ggagtgatga      600

tgatgatgat tttaacaaac ttcctaaaaa agctaaaggg aaagctcaaa aatcaaataa      660

gaagtgggat gggtcagagg aggatgagga taacagtaaa aaaattaaag agcgttcaag      720

aataaattct tctggtgaaa gtggtgatga atcagatgaa tttttgcaat ctagaaaagg      780

acagaaaaaa aatcagaaaa acaagccagg tcctaacata gaaagtggga atgaagatga      840

tgacgcctcc ttcaaaatta agacagtggc ccaaaagaag gcagaaaaga aggagcgcga      900

gagaaaaaag cgagatgaag aaaaagcgaa actgcggaag ctgaaagaaa aagaagagtt      960

agaaacaggt aaaaaggatc agagtaaaca aaaggaatct caaaggaaat ttgaagaaga     1020

aactgtaaaa tccaaagtga ctgttgatac tggagtaatt cctgcctctg aagagaaagc     1080

agagactccc acagctgcag aagatgacaa tgaaggagac aaaaagaaga aagataagaa     1140

gaaaaagaaa ggagaaaagg aagaaaaaga gaaagagaag aaaaaaggac ctagcaaagc     1200

cactgttaaa gctatgcaag aagctctggc taagcttaaa gaggaagaag aaagacagaa     1260

gagagaagag gaagaacgta taaaacggct tgaagaatta gaagccaagc gtaaagaaga     1320

ggaacgattg gaacaagaaa aaagagaaag gaaaaagcaa aaagaaaaag aaagaaaaga     1380

acgcttgaaa aaagaaggga aacttttaac taaatcccag agagaagcca gagccagagc     1440

cgaagctact cttaaactgc tacaagctca gggtgttgaa gtgccatcaa aagactcttt     1500

gccaaagaag aggccaattt atgaagataa aaagaggaaa aaaataccac agcagctaga     1560

aagtaaagaa gtgtctgaat caatggaatt atgtgctgct gtagaagtta tggaacaagg     1620

agtaccagaa aaggaagaga caccacctcc tgttgaacca gaagaagaag aagatactga     1680

ggatgctgga ttggatgatt gggaagctat ggccagtgat gaggagacag aaaaagtaga     1740

aggaaacaaa gttcatatag aagtaaaaga aaaccctgaa gaggaggagg aggaggaaga     1800

agaggaagaa gaagatgaag aaagtgaaga agaggaggaa gaggagggag aaagtgaagg     1860

cagtgaaggt gatgaggaag atgaaaaggt gtcagatgag aaggattcag ggaagacatt     1920

agataaaaag ccaagtaaag aaatgagctc agattctgaa tatgactctg atgatgatcg     1980

gactaaagaa gaaagggctt atgacaaagc aaaacggagg attgagaaac ggcgacttga     2040

acatagtaaa aatgtaaaca ccgaaaagct aagagcccct attatctgcg tacttgggca     2100

tgtggacaca gggaagacaa aaattctaga taagctccgt cacacacatg tacaagatgg     2160

tgaagcaggt ggtatcacac aacaaattgg ggccaccaat gttcctcttg aagctattaa     2220

tgaacagact aagatgatta aaaattttga tagagagaat gtacggattc caggaatgct     2280

aattattgat actcctgggc atgaatcttt cagtaatctg agaaatagag gaagctctct     2340

ttgtgacatt gccattttag ttgttgatat tatgcatggt ttggagcccc agacaattga     2400

gtctatcaac cttctcaaat ctaaaaaatg tcccttcatt gttgcactca ataagattga     2460

taggttatat gattggaaaa agagtcctga ctctgatgtg gctgctactt taaagaagca     2520

gaaaaagaat acaaaagatg aatttgagga gcgagcaaag gctattattg tagaatttgc     2580

acagcagggt ttgaatgctg ctttgtttta tgagaataaa gatccccgca cttttgtgtc     2640

tttggtacct acctctgcac atactggtga tggcatggga agtctgatct accttcttgt     2700

agagttaact cagaccatgt tgagcaagag acttgcacac tgtgaagagc tgagagcaca     2760

ggtgatggag gttaaagctc tcccggggat gggcaccact atagatgtca tcttgatcaa     2820

tgggcgtttg aaggaaggag atacaatcat tgttcctgga gtagaagggc ccattgtaac     2880

tcagattcga ggcctcctgt tacctcctcc tatgaaggaa ttacgagtga agaaccagta     2940

tgaaaagcat aaagaagtag aagcagctca gggggtaaag attcttggaa aagacctgga     3000

gaaaacattg gctggtttac ccctccttgt ggcttataaa gaagatgaaa tccctgttct     3060

taaagatgaa ttgatccatg agttaaagca gacactaaat gctatcaaat tagaagaaaa     3120

aggagtctat gtccaggcat ctacactggg ttctttggaa gctctactgg aatttctgaa     3180

aacatcagaa gtgccctatg caggaattaa cattggccca gtgcataaaa aagatgttat     3240

gaaggcttca gtgatgttgg aacatgaccc tcagtatgca gtaattttgg ccttcgatgt     3300

gagaattgaa cgagatgcac aagaaatggc tgatagttta ggagttagaa tttttagtgc     3360

agaaattatt tatcatttat ttgatgcctt tacaaaatat agacaagact acaagaaaca     3420

gaaacaagaa gaatttaagc acatagcagt atttccctgc aagataaaaa tcctccctca     3480

gtacattttt aattctcgag atccgatagt gatgggggtg acggtggaag caggtcaggt     3540

gaaacagggg acacccatgt gtgtcccaag caaaaatttt gttgacatcg gaatagtaac     3600

aagtattgaa ataaaccata aacaagtgga tgttgcaaaa aaaggacaag aagtttgtgt     3660

aaaaatagaa cctatccctg gtgagtcacc caaaatgttt ggaagacatt ttgaagctac     3720

agatattctt gttagtaaga tcagccggca gtccattgat gcactcaaag actggttcag     3780

agatgaaatg cagaagagtg actggcagct tattgtggag ctgaagaaag tatttgaaat     3840

catctaattt tttcacatgg agcaggaact ggagtaaatg caatactgtg ttgtaatatc     3900

ccaacaaaaa tcagacaaaa aatggaacag acgtatttgg acactgatgg acttaagtat     3960

ggaaggaaga aaaataggtg tataaaatgt tttccatgag aaaccaagaa acttacactg     4020

gtttgacagt ggtcagttac atgtccccac agttccaatg tgcctgttca ctcacctctc     4080

ccttccccaa cccttctcta cttggctgct gttttaaagt ttgcccttcc ccaaatttgg     4140

atttttatta cagatctaaa gctctttcga ttttatactg attaaatcag tactgcagta     4200

tttgattaac caagcttctg cagattttgt gattcttggg acttttttga cgtaagaaat     4260

acttctttat ttatgcatat tcttcccaca gtgatttttc cagcattctt ctgccatatg     4320

cctttagggc ttttataaaa tagaaaatta ggcattctga tatttcttta gctgctttgt     4380

gtgaaaccat ggtgtaaaag cacagctggc tgctttttac tgcttgtgta gtcacgagtc     4440

cattgtaatc atcacaattc taaaccaaac taccaataaa gaaaacagac atccaccagt     4500

aagcaagctc tgttaggctt ccatgttagt gtagcttctc tcccacaagt tgtcctccta     4560

ggacaagaat tatcttacaa actaaactat catcacacta ccttgtatgc cagcacctgg     4620

taacagtaga gatttttata cattaatctt gatctgtttt aatcttgatc tgttttagta     4680

gagattttta tacattaa                                                   4698


<210>  1682
<211>  7645
<212>  DNA
<213>  homo sapiens

<400>  1682
ggcgctgagc gagctcggag cccgcgctgt gcgcctgcgg ccggggcgcc ccgccgagcg       60

ccggtgcccc ggctcccggg ccgccttcgc cgcgcgggaa ggattcttca aaattaacag      120

aaaccaattc gggccagctg aagagaaaaa ataaaggtgg ctcccggctg cctctgctgc      180

agttcagagc aacttcagga gcttcccagc cgagagcttc aggacgcctt tcctgtccca      240

ctggcccagt tgccacaaca aacaacagag aagacggtga ccatggggga tgtgaagctg      300

gttgcctcgt cacacatttc caaaacctcc ctcagtgtgg atccctcaag agttgactcc      360

atgcccctga cagaggcccc tgctttcatt ttgccccctc ggaacctctg catcaaagaa      420

ggagccaccg ccaagttcga agggcgggtc cggggttacc cagagcccca ggtgacatgg      480

cacagaaacg ggcaacccat caccagcggg ggccgcttcc tgctggattg cggcatccgg      540

gggactttca gccttgtgat tcatgctgtc catgaggagg acaggggaaa gtatacctgt      600

gaagccacca atggcagtgg tgctcgccag gtgacagtgg agttgacagt agaaggaagt      660

tttgcgaagc agcttggtca gcctgttgtt tccaaaacct taggggatag attttcagct      720

ccagcagtgg agacccgtcc tagcatctgg ggggagtgcc caccaaagtt tgctaccaag      780

ctgggccgag ttgtggtcaa agaaggacag atgggacgat tctcctgcaa gatcactggc      840

cggccccaac cgcaggtcac ctggctcaag ggaaatgttc cactgcagcc gagtgcccgt      900

gtgtctgtgt ctgagaagaa cggcatgcag gttctggaaa tccatggagt caaccaagat      960

gacgtgggag tgtacacgtg cctggtggtg aacgggtcgg ggaaggcctc gatgtcagct     1020

gaactttcca tccaaggttt ggacagtgcc aataggtcat ttgtgagaga aacaaaagcc     1080

accaattcag atgtcaggaa agaggtgacc aatgtaatct caaaggagtc gaagctggac     1140

agtctggagg ctgcagccaa aagcaagaac tgctccagcc cccagagagg tggctcccca     1200

ccctgggctg caaacagcca gcctcagccc ccaagggagt ccaagctgga gtcatgcaag     1260

gactcgccca gaacggcccc gcagaccccg gtccttcaga agacttccag ctccatcacc     1320

ctgcaggccg caagagttca gccggaacca agagcaccag gcctgggggt cctatcacct     1380

tctggagaag agaggaagag gccagctcct ccccgtccag ccaccttccc caccaggcag     1440

cctggcctgg ggagccaaga tgttgtgagc aaggctgcta acaggagaat ccccatggag     1500

ggccagaggg attcagcatt ccccaaattt gagagcaagc cccaaagcca ggaggtcaag     1560

gaaaatcaaa ctgtcaagtt cagatgtgaa gggcttgccg tgatggaggt ggccccctcc     1620

ttctccagtg tcctgaagga ctgcgctgtt attgagggcc aggattttgt gctgcagtgc     1680

tccgtacggg ggaccccagt gccccggatc acttggctgc tgaatgggca gcccatccag     1740

tacgctcgct ccacctgcga ggccggcgtg gctgagctcc acatccagga tgccctgccg     1800

gaggaccatg gcacctacac ctgcctagct gagaatgcct tggggcaggt gtcctgcagc     1860

gcctgggtca ccgtccatga aaagaagagt agcaggaaga gtgagtacct tctgcctgtg     1920

gctcccagca agcccactgc acccatcttc ctgcagggcc tctctgatct caaagtcatg     1980

gatggaagcc aggtcactat gactgtccaa gtgtcaggga atccaccccc tgaagtcatc     2040

tggctgcaca atgggaatga gatccaagag tcagaggact tccactttga acagagagga     2100

actcagcaca gcctttgtat ccaggaagtg ttcccggagg acacgggcac gtacacctgc     2160

gaggcctgga acagcgctgg agaggtccgc acccaggccg tgctcacggt acaagagcct     2220

cacgatggca cccagccctg gttcatcagt aagcctcgct cagtgacagc ctccctgggc     2280

cagagtgtcc tcatctcctg cgccatagct ggtgacccct ttcctaccgt gcactggctc     2340

agagatggca aagccctctg caaagacact ggccacttcg aggtgcttca gaatgaggac     2400

gtgttcaccc tggttctaaa gaaggtgcag ccctggcatg ccggccagta tgagatcctg     2460

ctcaagaacc gggttggcga atgcagttgc caggtgtcac tgatgctaca gaacagctct     2520

gccagagccc ttccacgggg gagggagcct gccagctgcg aggacctctg tggtggagga     2580

gttggtgctg atggtggtgg tagtgaccgc tatgggtccc tgaggcctgg ctggccagca     2640

agagggcagg gttggctaga ggaggaagac ggcgaggacg tgcgaggggt gctgaagagg     2700

cgcgtggaga cgaggcagca cactgaggag gcgatccgcc agcaggaggt ggagcagctg     2760

gacttccgag acctcctggg gaagaaggtg agtacaaaga ccctatcgga agacgacctg     2820

aaggagatcc cagccgagca gatggatttc cgtgccaacc tgcagcggca agtgaagcca     2880

aagactgtgt ctgaggaaga gaggaaggtg cacagccccc agcaggtcga ttttcgctct     2940

gtcctggcca agaaggggac ttccaagacc cccgtgcctg agaaggtgcc accgccaaaa     3000

cctgccaccc cggattttcg ctcagtgctg ggtggcaaga agaaattacc agcagagaat     3060

ggcagcagca gtgccgagac cctgaatgcc aaggcagtgg agagttccaa gcccctgagc     3120

aatgcacagc cttcagggcc cttgaaaccc gtgggcaacg ccaagcctgc tgagaccctg     3180

aagccaatgg gcaacgccaa gcctgccgag accctgaagc ccatgggcaa tgccaagcct     3240

gatgagaacc tgaaatccgc tagcaaagaa gaactcaaga aagacgttaa gaatgatgtg     3300

aactgcaaga gaggccatgc agggaccaca gataatgaaa agagatcaga gagccagggg     3360

acagccccag ccttcaagca gaagctgcaa gatgttcatg tggcagaggg caagaagctg     3420

ctgctccagt gccaggtgtc ttctgacccc ccagccacca tcatctggac gctgaacgga     3480

aagaccctca agaccaccaa gttcatcatc ctctcccagg aaggctcact ctgctccgtc     3540

tccatcgaga aggcactgcc tgaggacaga ggcttataca agtgtgtagc caagaatgac     3600

gctggccagg cggagtgctc ctgccaagtc accgtggatg atgctccagc cagtgagaac     3660

accaaggccc cagagatgaa atcccggagg cccaagagct ctcttcctcc cgtgctagga     3720

actgagagtg atgcgactgt gaaaaagaaa cctgccccca agacacctcc gaaggcagca     3780

atgccccctc agatcatcca gttccctgag gaccagaagg tacgcgcagg agagtcagtg     3840

gagctgtttg gcaaagtgac aggcactcag cccatcacct gtacctggat gaagttccga     3900

aagcagatcc aggaaagcga gcacatgaag gtggagaaca gcgagaatgg cagcaagctc     3960

accatcctgg ccgcgcgcca ggagcactgc ggctgctaca cactgctggt ggagaacaag     4020

ctgggcagca ggcaggccca ggtcaacctc actgtcgtgg ataagccaga ccccccagct     4080

ggcacacctt gtgcctctga cattcggagc tcctcactga ccctgtcctg gtatggctcc     4140

tcatatgatg ggggcagtgc tgtacagtcc tacagcatcg agatctggga ctcagccaac     4200

aagacgtgga aggaactagc cacatgccgc agcacctctt tcaacgtcca ggacctgctg     4260

cctgaccacg aatataagtt ccgtgtacgt gcaatcaacg tgtatggaac cagtgagcca     4320

agccaggagt ctgaactcac aacggtagga gagaaacctg aagagccgaa ggatgaagtg     4380

gaggtgtcag atgatgatga gaaggagccc gaggttgatt accggacagt gacaatcaat     4440

actgaacaaa aagtatctga cttctacgac attgaggaga gattaggatc tgggaaattt     4500

ggacaggtct ttcgacttgt agaaaagaaa actcgaaaag tctgggcagg gaagttcttc     4560

aaggcatatt cagcaaaaga gaaagagaat atccggcagg agattagcat catgaactgc     4620

ctccaccacc ctaagctggt ccagtgtgtg gatgcctttg aagaaaaggc caacatcgtc     4680

atggtcctgg agatcgtgtc aggaggggag ctgtttgagc gcatcattga cgaggacttt     4740

gagctgacgg agcgtgagtg catcaagtac atgcggcaga tctcggaggg agtggagtac     4800

atccacaagc agggcatcgt gcacctggac ctcaagccgg agaacatcat gtgtgtcaac     4860

aagacgggca ccaggatcaa gctcatcgac tttggtctgg ccaggaggct ggagaatgcg     4920

gggtctctga aggtcctctt tggcacccca gaatttgtgg ctcctgaagt gatcaactat     4980

gagcccatcg gctacgccac agacatgtgg agcatcgggg tcatctgcta catcctagtc     5040

agtggccttt cccccttcat gggagacaac gataacgaaa ccttggccaa cgttacctca     5100

gccacctggg acttcgacga cgaggcattc gatgagatct ccgacgatgc caaggatttc     5160

atcagcaatc tgctgaagaa agatatgaaa aaccgcctgg actgcacgca gtgccttcag     5220

catccatggc taatgaaaga taccaagaac atggaggcca agaaactctc caaggaccgg     5280

atgaagaagt acatggcaag aaggaaatgg cagaaaacgg gcaatgctgt gagagccatt     5340

ggaagactgt cctctatggc aatgatctca gggctcagtg gcaggaaatc ctcaacaggg     5400

tcaccaacca gcccgctcaa tgcagaaaaa ctagaatctg aagaagatgt gtcccaagct     5460

ttccttgagg ctgttgctga ggaaaagcct catgtaaaac cctatttctc taagaccatt     5520

cgcgatttag aagttgtgga gggaagtgct gctagatttg actgcaagat tgaaggatac     5580

ccagaccccg aggttgtctg gttcaaagat gaccagtcaa tcagggagtc ccgccacttc     5640

cagatagact acgatgagga cgggaactgc tctttaatta ttagtgatgt ttgcggggat     5700

gacgatgcca agtacacctg caaggctgtc aacagtcttg gagaagccac ctgcacagca     5760

gagctcattg tggaaacgat ggaggaaggt gaaggggaag gggaagagga agaagagtga     5820

aacaaagcca gagaaaagca gtttctaagt catattaaaa ggactatttc tctaaaactc     5880

aaaaaaaaaa aaaaaactca agatagtaaa agcacctagt gtgatagatt atcggttagg     5940

tcatttgtgg gttgattctt cagaaacagc agttgatacc tagcagcgtt attgatgggc     6000

attaatctat gttagttggc accttaagat actagtgcag ctagatttca tttagggaaa     6060

tcaccagtaa cttgactgac caattgattt tagagagaaa gtaaccaaac caaatattta     6120

tctgggcaaa gtcataaatt ctccacttga atgcgctcat gaaaaataag gccaaaacaa     6180

gagttctggg ccacagctca gcccagaggg ttcctgggga tgggaggcct ctctctcccc     6240

accccctgac tctagagaac tgggttttct cccagtactc cagcaattca tttctgaaag     6300

cagttgagcc actttattcc aaagtacact gcagatgttc aaactctcca tttctctttc     6360

cccttccacc tgccagtttt gctgactctc aacttgtcat gagtgtaagc attaaggaca     6420

ttatgcttct tcgattctga agacaggtcc ctgctcatgg atgactctgg cttccttagg     6480

aaaatatttt tcttccaaaa tcagtaggaa atctaaactt atcccctctt tgcagatgtc     6540

tagcagcttc agacatttgg ttaagaaccc atgggaaaaa aaaaatcctt gctaatgtgg     6600

tttcctttgt aaaccaggat tcttatttgt gctgttatag aatatcagct ctgaacgtgt     6660

ggtaaagatt tttgtgtttg aatataggag aaatcagttt gctgaaaagt tagtcttaat     6720

tatctattgg ccacgatgaa acagatttca actgataaag agctggagaa ctccatgtac     6780

tttggaatct cctccaagat agccagagtt taatacatct tcattctcaa cactctccaa     6840

agaacttgac ctaccttatg ggttccatat ttttcttctt aaatgtgcat caatcatgcc     6900

ttgcccccaa cctttaaata tattcttaga cctggtaaat gcactcagac ttgcgtcttt     6960

aggaattttt aactttcttt cactacattg gcacttaaat tttttcttta taaagctttt     7020

tgaaggtcat aaacaaagac cataattgat gatagaccta atacatttcc tctgtgtgtg     7080

tgtgtaacat tccaaatact ttttttttct tttccactgt ttgtaaggtg caacaattta     7140

atatttttaa gggacttttt aagagttcct taagaaccaa tttaaaatta cttcagtgca     7200

atcctacaca gtatcaacat tagaattttg atattagtct tatgttatct tccattctat     7260

ttttatctgc tttttgctgc tagtttcaaa ctgccagtat ttttcctttt gcttttaaaa     7320

tagttacaat atttttcatg atagccacag tattgccaca gtttattata ataaagggtt     7380

tttatttgat ttagcgcatt caaagctttt ttctatcact tttgtgttca gaatataacc     7440

tttgtgtgcg tgtatgttgt gtgtgtgcat gtgtggcgta tatgtgtgtt acaggttaat     7500

gccttcttgg aattgtgtta atgttctctt ggtttattat gccatcagaa tggtaaatga     7560

gaacactaca actgtagtca gctcacaatt tttaaataaa ggataccaca gtgcatgctg     7620

tttgttcaaa aaaaaaaaaa aaaaa                                           7645


<210>  1683
<211>  7492
<212>  DNA
<213>  homo sapiens

<400>  1683
ggcgctgagc gagctcggag cccgcgctgt gcgcctgcgg ccggggcgcc ccgccgagcg       60

ccggtgcccc ggctcccggg ccgccttcgc cgcgcgggaa ggattcttca aaattaacag      120

aaaccaattc gggccagctg aagagaaaaa ataaaggtgg ctcccggctg cctctgctgc      180

agttcagagc aacttcagga gcttcccagc cgagagcttc aggacgcctt tcctgtccca      240

ctggcccagt tgccacaaca aacaacagag aagacggtga ccatggggga tgtgaagctg      300

gttgcctcgt cacacatttc caaaacctcc ctcagtgtgg atccctcaag agttgactcc      360

atgcccctga cagaggcccc tgctttcatt ttgccccctc ggaacctctg catcaaagaa      420

ggagccaccg ccaagttcga agggcgggtc cggggttacc cagagcccca ggtgacatgg      480

cacagaaacg ggcaacccat caccagcggg ggccgcttcc tgctggattg cggcatccgg      540

gggactttca gccttgtgat tcatgctgtc catgaggagg acaggggaaa gtatacctgt      600

gaagccacca atggcagtgg tgctcgccag gtgacagtgg agttgacagt agaaggaagt      660

tttgcgaagc agcttggtca gcctgttgtt tccaaaacct taggggatag attttcagct      720

ccagcagtgg agacccgtcc tagcatctgg ggggagtgcc caccaaagtt tgctaccaag      780

ctgggccgag ttgtggtcaa agaaggacag atgggacgat tctcctgcaa gatcactggc      840

cggccccaac cgcaggtcac ctggctcaag ggaaatgttc cactgcagcc gagtgcccgt      900

gtgtctgtgt ctgagaagaa cggcatgcag gttctggaaa tccatggagt caaccaagat      960

gacgtgggag tgtacacgtg cctggtggtg aacgggtcgg ggaaggcctc gatgtcagct     1020

gaactttcca tccaaggttt ggacagtgcc aataggtcat ttgtgagaga aacaaaagcc     1080

accaattcag atgtcaggaa agaggtgacc aatgtaatct caaaggagtc gaagctggac     1140

agtctggagg ctgcagccaa aagcaagaac tgctccagcc cccagagagg tggctcccca     1200

ccctgggctg caaacagcca gcctcagccc ccaagggagt ccaagctgga gtcatgcaag     1260

gactcgccca gaacggcccc gcagaccccg gtccttcaga agacttccag ctccatcacc     1320

ctgcaggccg caagagttca gccggaacca agagcaccag gcctgggggt cctatcacct     1380

tctggagaag agaggaagag gccagctcct ccccgtccag ccaccttccc caccaggcag     1440

cctggcctgg ggagccaaga tgttgtgagc aaggctgcta acaggagaat ccccatggag     1500

ggccagaggg attcagcatt ccccaaattt gagagcaagc cccaaagcca ggaggtcaag     1560

gaaaatcaaa ctgtcaagtt cagatgtgaa gggcttgccg tgatggaggt ggccccctcc     1620

ttctccagtg tcctgaagga ctgcgctgtt attgagggcc aggattttgt gctgcagtgc     1680

tccgtacggg ggaccccagt gccccggatc acttggctgc tgaatgggca gcccatccag     1740

tacgctcgct ccacctgcga ggccggcgtg gctgagctcc acatccagga tgccctgccg     1800

gaggaccatg gcacctacac ctgcctagct gagaatgcct tggggcaggt gtcctgcagc     1860

gcctgggtca ccgtccatga aaagaagagt agcaggaaga gtgagtacct tctgcctgtg     1920

gctcccagca agcccactgc acccatcttc ctgcagggcc tctctgatct caaagtcatg     1980

gatggaagcc aggtcactat gactgtccaa gtgtcaggga atccaccccc tgaagtcatc     2040

tggctgcaca atgggaatga gatccaagag tcagaggact tccactttga acagagagga     2100

actcagcaca gcctttgtat ccaggaagtg ttcccggagg acacgggcac gtacacctgc     2160

gaggcctgga acagcgctgg agaggtccgc acccaggccg tgctcacggt acaagagcct     2220

cacgatggca cccagccctg gttcatcagt aagcctcgct cagtgacagc ctccctgggc     2280

cagagtgtcc tcatctcctg cgccatagct ggtgacccct ttcctaccgt gcactggctc     2340

agagatggca aagccctctg caaagacact ggccacttcg aggtgcttca gaatgaggac     2400

gtgttcaccc tggttctaaa gaaggtgcag ccctggcatg ccggccagta tgagatcctg     2460

ctcaagaacc gggttggcga atgcagttgc caggtgtcac tgatgctaca gaacagctct     2520

gccagagccc ttccacgggg gagggagcct gccagctgcg aggacctctg tggtggagga     2580

gttggtgctg atggtggtgg tagtgaccgc tatgggtccc tgaggcctgg ctggccagca     2640

agagggcagg gttggctaga ggaggaagac ggcgaggacg tgcgaggggt gctgaagagg     2700

cgcgtggaga cgaggcagca cactgaggag gcgatccgcc agcaggaggt ggagcagctg     2760

gacttccgag acctcctggg gaagaaggtg agtacaaaga ccctatcgga agacgacctg     2820

aaggagatcc cagccgagca gatggatttc cgtgccaacc tgcagcggca agtgaagcca     2880

aagactgtgt ctgaggaaga gaggaaggtg cacagccccc agcaggtcga ttttcgctct     2940

gtcctggcca agaaggggac ttccaagacc cccgtgcctg agaaggtgcc accgccaaaa     3000

cctgccaccc cggattttcg ctcagtgctg ggtggcaaga agaaattacc agcagagaat     3060

ggcagcagca gtgccgagac cctgaatgcc aaggcagtgg agagttccaa gcccctgagc     3120

aatgcacagc cttcagggcc cttgaaaccc gtgggcaacg ccaagcctgc tgagaccctg     3180

aagccaatgg gcaacgccaa gcctgccgag accctgaagc ccatgggcaa tgccaagcct     3240

gatgagaacc tgaaatccgc tagcaaagaa gaactcaaga aagacgttaa gaatgatgtg     3300

aactgcaaga gaggccatgc agggaccaca gataatgaaa agagatcaga gagccagggg     3360

acagccccag ccttcaagca gaagctgcaa gatgttcatg tggcagaggg caagaagctg     3420

ctgctccagt gccaggtgtc ttctgacccc ccagccacca tcatctggac gctgaacgga     3480

aagaccctca agaccaccaa gttcatcatc ctctcccagg aaggctcact ctgctccgtc     3540

tccatcgaga aggcactgcc tgaggacaga ggcttataca agtgtgtagc caagaatgac     3600

gctggccagg cggagtgctc ctgccaagtc accgtggatg atgctccagc cagtgagaac     3660

accaaggccc cagagatgaa atcccggagg cccaagagct ctcttcctcc cgtgctagga     3720

actgagagtg atgcgactgt gaaaaagaaa cctgccccca agacacctcc gaaggcagca     3780

atgccccctc agatcatcca gttccctgag gaccagaagg tacgcgcagg agagtcagtg     3840

gagctgtttg gcaaagtgac aggcactcag cccatcacct gtacctggat gaagttccga     3900

aagcagatcc aggaaagcga gcacatgaag gtggagaaca gcgagaatgg cagcaagctc     3960

accatcctgg ccgcgcgcca ggagcactgc ggctgctaca cactgctggt ggagaacaag     4020

ctgggcagca ggcaggccca ggtcaacctc actgtcgtgg ataagccaga ccccccagct     4080

ggcacacctt gtgcctctga cattcggagc tcctcactga ccctgtcctg gtatggctcc     4140

tcatatgatg ggggcagtgc tgtacagtcc tacagcatcg agatctggga ctcagccaac     4200

aagacgtgga aggaactagc cacatgccgc agcacctctt tcaacgtcca ggacctgctg     4260

cctgaccacg aatataagtt ccgtgtacgt gcaatcaacg tgtatggaac cagtgagcca     4320

agccaggagt ctgaactcac aacggtagga gagaaacctg aagagccgaa ggatgaagtg     4380

gaggtgtcag atgatgatga gaaggagccc gaggttgatt accggacagt gacaatcaat     4440

actgaacaaa aagtatctga cttctacgac attgaggaga gattaggatc tgggaaattt     4500

ggacaggtct ttcgacttgt agaaaagaaa actcgaaaag tctgggcagg gaagttcttc     4560

aaggcatatt cagcaaaaga gaaagagaat atccggcagg agattagcat catgaactgc     4620

ctccaccacc ctaagctggt ccagtgtgtg gatgcctttg aagaaaaggc caacatcgtc     4680

atggtcctgg agatcgtgtc aggaggggag ctgtttgagc gcatcattga cgaggacttt     4740

gagctgacgg agcgtgagtg catcaagtac atgcggcaga tctcggaggg agtggagtac     4800

atccacaagc agggcatcgt gcacctggac ctcaagccgg agaacatcat gtgtgtcaac     4860

aagacgggca ccaggatcaa gctcatcgac tttggtctgg ccaggaggct ggagaatgcg     4920

gggtctctga aggtcctctt tggcacccca gaatttgtgg ctcctgaagt gatcaactat     4980

gagcccatcg gctacgccac agacatgtgg agcatcgggg tcatctgcta catcctaaac     5040

cgcctggact gcacgcagtg ccttcagcat ccatggctaa tgaaagatac caagaacatg     5100

gaggccaaga aactctccaa ggaccggatg aagaagtaca tggcaagaag gaaatggcag     5160

aaaacgggca atgctgtgag agccattgga agactgtcct ctatggcaat gatctcaggg     5220

ctcagtggca ggaaatcctc aacagggtca ccaaccagcc cgctcaatgc agaaaaacta     5280

gaatctgaag aagatgtgtc ccaagctttc cttgaggctg ttgctgagga aaagcctcat     5340

gtaaaaccct atttctctaa gaccattcgc gatttagaag ttgtggaggg aagtgctgct     5400

agatttgact gcaagattga aggataccca gaccccgagg ttgtctggtt caaagatgac     5460

cagtcaatca gggagtcccg ccacttccag atagactacg atgaggacgg gaactgctct     5520

ttaattatta gtgatgtttg cggggatgac gatgccaagt acacctgcaa ggctgtcaac     5580

agtcttggag aagccacctg cacagcagag ctcattgtgg aaacgatgga ggaaggtgaa     5640

ggggaagggg aagaggaaga agagtgaaac aaagccagag aaaagcagtt tctaagtcat     5700

attaaaagga ctatttctct aaaactcaaa aaaaaaaaaa aaactcaaga tagtaaaagc     5760

acctagtgtg atagattatc ggttaggtca tttgtgggtt gattcttcag aaacagcagt     5820

tgatacctag cagcgttatt gatgggcatt aatctatgtt agttggcacc ttaagatact     5880

agtgcagcta gatttcattt agggaaatca ccagtaactt gactgaccaa ttgattttag     5940

agagaaagta accaaaccaa atatttatct gggcaaagtc ataaattctc cacttgaatg     6000

cgctcatgaa aaataaggcc aaaacaagag ttctgggcca cagctcagcc cagagggttc     6060

ctggggatgg gaggcctctc tctccccacc ccctgactct agagaactgg gttttctccc     6120

agtactccag caattcattt ctgaaagcag ttgagccact ttattccaaa gtacactgca     6180

gatgttcaaa ctctccattt ctctttcccc ttccacctgc cagttttgct gactctcaac     6240

ttgtcatgag tgtaagcatt aaggacatta tgcttcttcg attctgaaga caggtccctg     6300

ctcatggatg actctggctt ccttaggaaa atatttttct tccaaaatca gtaggaaatc     6360

taaacttatc ccctctttgc agatgtctag cagcttcaga catttggtta agaacccatg     6420

ggaaaaaaaa aatccttgct aatgtggttt cctttgtaaa ccaggattct tatttgtgct     6480

gttatagaat atcagctctg aacgtgtggt aaagattttt gtgtttgaat ataggagaaa     6540

tcagtttgct gaaaagttag tcttaattat ctattggcca cgatgaaaca gatttcaact     6600

gataaagagc tggagaactc catgtacttt ggaatctcct ccaagatagc cagagtttaa     6660

tacatcttca ttctcaacac tctccaaaga acttgaccta ccttatgggt tccatatttt     6720

tcttcttaaa tgtgcatcaa tcatgccttg cccccaacct ttaaatatat tcttagacct     6780

ggtaaatgca ctcagacttg cgtctttagg aatttttaac tttctttcac tacattggca     6840

cttaaatttt ttctttataa agctttttga aggtcataaa caaagaccat aattgatgat     6900

agacctaata catttcctct gtgtgtgtgt gtaacattcc aaatactttt tttttctttt     6960

ccactgtttg taaggtgcaa caatttaata tttttaaggg actttttaag agttccttaa     7020

gaaccaattt aaaattactt cagtgcaatc ctacacagta tcaacattag aattttgata     7080

ttagtcttat gttatcttcc attctatttt tatctgcttt ttgctgctag tttcaaactg     7140

ccagtatttt tccttttgct tttaaaatag ttacaatatt tttcatgata gccacagtat     7200

tgccacagtt tattataata aagggttttt atttgattta gcgcattcaa agcttttttc     7260

tatcactttt gtgttcagaa tataaccttt gtgtgcgtgt atgttgtgtg tgtgcatgtg     7320

tggcgtatat gtgtgttaca ggttaatgcc ttcttggaat tgtgttaatg ttctcttggt     7380

ttattatgcc atcagaatgg taaatgagaa cactacaact gtagtcagct cacaattttt     7440

aaataaagga taccacagtg catgctgttt gttcaaaaaa aaaaaaaaaa aa             7492


<210>  1684
<211>  2100
<212>  DNA
<213>  homo sapiens

<400>  1684
gcggaagtgg cggcggcgcc ggcctggcct ggcctggctg aggggaggcg gcgggcgggc       60

gcgatggcgg aggccgggcc acaggcgccg ccgcccccgg gcactccaag ccggcacgaa      120

aagagcctgg gactgctcac caccaagttc gtgtcccttc tgcaggaggc caaggacggc      180

gtgcttgacc tcaagctggc agctgacacc ctagctgtac gccagaagcg gcggatttac      240

gacattacca atgttttgga aggtatcggg ctaatcgaga aaaagtccaa gaacagcatc      300

cagtggaagg gtgtggggcc tggctgcaat acccgggaga ttgctgacaa actgattgag      360

ctcaaggcag agatcgagga gctgcagcag cgggagcaag aactagacca gcacaaggtg      420

tgggtgcagc agagcatccg gaacgtcaca gaggacgtgc agaacagctg tttggcctac      480

gtcactcatg aggacatctg cagatgcttt gctggagata ccctcttggc catccgggcc      540

ccatcaggca ccagcctgga ggtgcccatc ccagagggtc tcaatgggca gaagaagtac      600

cagattcacc tgaagagtgt gagtggtccc attgaggttc tgctggtgaa caaggaggca      660

tggagctcac cccctgtggc tgtgcctgtg ccaccacctg aagatttgct ccagagccca      720

tctgctgttt ctacacctcc acctctgccc aagcctgccc tagcccagtc ccaggaagcc      780

tcacgtccaa atagtcctca gctcactccc actgctgtcc ctggcagtgc agaagtccag      840

ggaatggctg gcccagcagc tgagatcaca gtgagtggcg gccctgggac tgatagcaag      900

gacagtggtg agctcagttc actcccactg ggcccaacaa cactggacac ccggccactg      960

cagtcttctg ccctgctgga cagcagcagc agcagcagca gcagcagcag cagcagcagc     1020

aacagtaaca gcagcagttc gtccggaccc aacccttcta cctcctttga gcccatcaag     1080

gcagacccca caggtgtttt ggaactcccc aaagagctgt cagaaatctt tgatcccaca     1140

cgagagtgca tgagctcgga gctgctggag gagttgatgt cctcagaagt gtttgcccct     1200

ctgcttcgtc tttctccacc cccgggagac cacgattata tctacaacct ggacgagagt     1260

gaaggtgtct gtgacctctt tgatgtgcct gttctcaacc tctgactgac agggacatgc     1320

cctgtgtggc tgggacccag actgtctgac ctgggggttg cctggggacc tctcccaccc     1380

gacccctaca gagcttgaga gccacagacg cctggcttct ccggcctccc ctcaccgcac     1440

agttctggcc acagctcccg ctcctgtgct ggcacttctg tgctcgcaga gcaggggaac     1500

aggactcagc ccccatcacc gtggagccaa agtgtttgct tctccctttc tgcggccttc     1560

gccagcccag gctcggctgc cacccagtgg cacagaaccg aggagctgcc attacccccc     1620

atagggggca gtgtcttgtt cctgccagcc tcagtgtctt gcttctgcca gctccttccc     1680

ctaggaggga agggtggggt ggaactgggc acatgccagc accacttcta gcttccttcg     1740

ctatccccca ccccctgacc ctccagctcc tcctggccct ctcacgtgcc cacttctgct     1800

gggcctttag ccctagaacc tgcaggtggt gggggcggct accaagaagg aacagaggtc     1860

tctggggagg agtctgggtg gtccagccct gatgattggc cccacctcct gctgccccat     1920

aaccctctct tcatttcggc tttttcattt accctcattt agagccattt gcagagattt     1980

agaaagattt acagtaacga atggattcct atataaagat tatttttata ctttttgcag     2040

caaaaggaaa ttgtaatatt tgtacagtgt tcaagtgaat aaaaaccatg cctaaggcta     2100


<210>  1685
<211>  5507
<212>  DNA
<213>  homo sapiens

<400>  1685
gtaatgctga gacagactcc cagaagatct gagcgagtcg cgtagctgag cccggcaggg       60

gctggggtgg tgctgctgct atgagctgca ccatcgagaa gatcctgaca gacgccaaga      120

cgctgctgga gaggctacgg gagcacgatg cggccgccga gtcgctggtg gatcagtcgg      180

cggcgctgca ccggcgggta gcagctatgc gggaggcggg gacagcgctt ccggaccagt      240

atcaagagga tgcatccgat atgaaggaca tgtccaaata caaacctcac attctgctgt      300

cccaagagaa cacacagatt agagacttgc aacaggaaaa cagagagcta tggatttcct      360

tggaggaaca ccaggatgct ttggaactta tcatgagcaa atatcggaaa cagatgttac      420

agttaatggt tgctaaaaaa gcggtggatg ctgaaccagt cctgaaagct caccagtctc      480

actctgcaga aattgagagt cagattgaca gaatctgtga aatgggagaa gtgatgagga      540

aagcagttca ggtggatgat gaccagtttt gtaagattca ggaaaaatta gcccaattag      600

agcttgaaaa taaggaactt cgagaattat tgtccatcag cagtgagtct cttcaagcca      660

gaaaggaaaa ctcaatggac actgcttccc aagccatcaa ataactgaac tctgaatgat      720

ggctggagat tgtctatcaa ggaaggaagt tactgtcttc ccattcaagt actgtccatt      780

aagtgtcttg cctcagattt gatttaatct taattaaagg tatcaggtgg caatttagaa      840

ttccagtcaa tattggctgt ccacagttct cagatgtgtt aatgtgaata ctacatgctg      900

aatttcacca ttcctttctc aaagagacta cttttaattt tcatttctgg gaccttgatt      960

tatataaact atgttttcag ttctttgtta tttttcacat ctctgaaact ttgagcattt     1020

tttataagcc agcaatttat tttacatagc attgtaaaat acacttctag gaaattttag     1080

gaaagattta actgtttaaa tctatttggc ataaaccttg attttttttt tccatttgac     1140

aaaaataata caattccaca gaactagatc agcagattct ctgatttgta atgtcattca     1200

cctgtgacat tttaagtctc tctggtgcta agaattggca ctttatagcc tggtgccttt     1260

acttttaatt tgagagaacc tactgctagt cccaggaaac acacttggaa ataagtcagc     1320

tatttttttt gcccagtgat gctatagttg tcatattgtc caaagttcat attgttcaaa     1380

gctgaggagc ttgtcctgtg tatgtgaatg cacacatgtg cacttagttc aaatactaaa     1440

agtagctttt attaaatata atcagccaaa aacacacaca aaataaaaaa aacaaatata     1500

agtagtcagt ttttcaatgt tatcctacta gttctacatt ctattttaat ttttatacaa     1560

tttccatttt atagttaaga accatcactt acttggattg gatgtctttc attcctagca     1620

ctaatagttg gctttctttt tttttgttta catagaagca gggttttttt ttatcttttt     1680

tctttttttt tgtttaagct atataaaaag gtgaggaagc agttttgtta cctaatgaaa     1740

attattacac tcataatgct gtgtaggcaa cattgagatt caaatgccca gtggtcaact     1800

gggttcactc atcaactcat tcccgtccca gtttactcac atttcaaatt tataaatttc     1860

ttcatgttat actattctat ttagatttgc ccagaattag ttgaaataat gctaaacctg     1920

tcaatatttt ccagtaacat taagcaccat actgcatggg agagacacag tactaaaaag     1980

agttgttagt gctttatgtg agtgatattt ctttcgtaat gctataaaga actacagtta     2040

aaataacaaa atattttaaa gatgtcctaa aagcatctga tcccagtaat aactaatgga     2100

tgtcatctag agcagtgggt gttaatgaat aggtatatgt catttaagaa tttttcaaat     2160

ttctgtttga tatcctgcat agaatttgac aaaaaaaaca cttccaagtg tgagcatttt     2220

ttatttcatt tcccaagagt aagtaagtaa ctattagccc agccatctgc ctcgaagtat     2280

accttaagtg accccataaa tccattcaag aggcaggtac tctataccat ttggcagcca     2340

cggccaaacc taccatggcc agatttcagt gaaaatgatg aagtaatcaa atcaaggtat     2400

aatatggtgt ccctttatgt gctttatgtt cctttagagc tgtttataaa gttctttata     2460

tctcaagtgt taggataaat cgacatacta acttttcccc ctgcaaaatt aaaagcctga     2520

ggtacaagtc taagaagctt ttagtgctct acataatata aattctggct ggtgttaatg     2580

ctatgaagat aatatgtagt tagaaaattg agtcggggag gaatgctctt cattttaagt     2640

ggattttaaa gtttctcctt gagtggatga agaacttgcc tggtttgcaa aaatcttagt     2700

tcaaaattat attttctaac aaaaactgca ttttgagaag ataagctaat tttactcagt     2760

agtaagtcaa atgaggaagt gcagagggtt tttttacata tatatagcaa ccttgtcaag     2820

tggtcctcac aagagtcata aatactttgt aattagcaca gtatattcag cagtgtataa     2880

ctctacaaat agtaccttat attagtgtag tattatatca atatcttatg tataattctt     2940

atattaatac cttatgcata attggattca aacattgaag gtctatttta gtgttcttca     3000

aaatgtgctt ccctgaccta ctgaaataga aacttggtga tgaagttcaa gaatttgtat     3060

tctaatcatc tcaaacaatt cctaaagaca ctgattttaa aatatctagt ctaggcccca     3120

ttgtgtaata gttagcactc taaaagatga aaaagaaaat agtctatgtg ccaaccactt     3180

cattagtact tatgaattta aaaatgaaaa agtctggtac aggagacaag tatatatata     3240

aaattataat gcagtgtgat aaatccatta tagtatgtat aagatacaga agagggactt     3300

taaacttgag aattcaatag agataataaa tgggtaggag ggaaatagaa aactttggtg     3360

ccacaaaagc aaagtatgta tggtattgcc aataatagct accatctatt gagtgcttta     3420

ctacctgtca ggtactgtat tatataaact ccattttaac tgtacctcat tttgcagata     3480

ctcaggcaca aggaggtggt tatttgtcca aactggaacc aagattcaaa cccagacaga     3540

gtcttaagca catttttaat cactaactaa cttgagatgc ctaaatgcca aatactgttg     3600

ggagttcaag tggttcttga ttagcaaaat ctatttttat tagtgcaaaa gaaacaccac     3660

agcttataaa gtattatgaa ttcaataaat ggagtcttaa ctaatgagat attattttct     3720

agaatggtgt agctgagagt atgtgtgatt caactgaaag gaataatgtt taatcagtga     3780

ctcttactat atacaggaaa aggtgcagtt ctgtctttca aatctgcctc cttaccatat     3840

tggcttacat ccctcatgct gttttcttgt gtttgctaga aagttgttgc caagccaaat     3900

gtcatggcca tgttgaaggc aaggaagaaa aaatggaaat ggcctgtgcc agctatatat     3960

atcgcctttt atgagggaaa gcaaagcttt ctcagaaatc ccaaatggat tttcccttga     4020

cttaattgcc tgaccagtta aatggccact ggtacctgca aagaaagcag ggtacatagc     4080

tgtcccaaat aaaatcagta ttagcaagaa gaaagaatat tgagaaagca attaacagtg     4140

tctgtgactg tgacatgtct gtgactttat attgtcaagt cctttcccct tgaatatagt     4200

tttggaagaa ttagctgaag gagtgtgttg acattgaatg gccaagagaa tgggctgtag     4260

cagacatctg tcatttctct tttggctgcc cagtatccta actcctgtgt ttaaggaatc     4320

cctcacctaa tgaggcagag catttcttcc tcctaaagaa tttgaaagta ccaggtaatg     4380

ttttctcagc ctccttttgc agctaaggaa gaaacatctg ccttcaattt taaaattagt     4440

gatacaaaga aggagggaac catgcagatt cctttgaaga tggtgattaa caacactact     4500

gcattcatct ccacagaggt acagcaaaag tgatttagtt agcgataacc tctaattcta     4560

tttttttatt tttatttttt gagacagtct tgctctgtca accaggctgg agtgcagtag     4620

cactgtctta actcactgca acctccacct cctgggttca agcgattctc ctgcctcagc     4680

ctcccaagtc gctgggatta caagtgccca ccaccatgca cagctaattt ttgtgttttt     4740

agtagatggg gtttctccat gttggccagg ctggtctcga acttatgact tcaggtgatc     4800

cgcccgcctt ggcctcccaa agtgctggga ttataggcgt gagccactgt gcctggcctg     4860

taacctctaa ttcttgtttg ctggctgtcc tagagatcct gagaattact tttaataaaa     4920

tcattttttt gctgttatta aaactaacct gaattgccta aaaccaagaa ctctgcttga     4980

taaaataagc atagttttag gaacagccat gcagatataa attttatcaa cactttatac     5040

ataatttggg acttatattt aaatgtaata tttgatgctt ataaaagggt aaatggggaa     5100

tgcaaataaa ttatcaagca taataactca tcacctaact taagaataac attatgagtg     5160

cttgtatttt atctatttga gctcttctcc tatctttgcc gacccccccg ctctcttttt     5220

aatagatttg ttcgaatgta gaaagaccta aaatacatat gtatccctaa agtgacttat     5280

tttatagttt tctttctttt tgaacttcaa aaaaattgta tcatactcta tgtagtctaa     5340

ggatttggtt tttttcactc aacatgtctc tagaattcac aagttttatt gttttatagc     5400

tgtcattttc attgatgtat atttcattgt tgggttatac aacatattgt taaggaatac     5460

atacatatat aataaattat acatttttta aaaaaaaaaa aaaaaaa                   5507


<210>  1686
<211>  6337
<212>  DNA
<213>  homo sapiens

<400>  1686
aggccccacc cgctggtggc ccggtccgcg tgtgcgccga ctctcgcact ctcctcgctc       60

cgggcgccca gactctgaga gagagcgacg gccatcatag aacagcgaag gcagtcgatc      120

ggcctgcggt ccgcttcggc attcgcaggc cgcaggcggg aggctagagc ccccaggcgc      180

acctcgcccc aaccgcccgc ggctcgggca gctctgcaga gacgtcgtgg cggcagggcc      240

agcacccatt ggtccgccac agccctccgc cctccccctc gccacgctta ttggccggag      300

cggcggcgct cgccgggtag gcggtggcgg cgtccctccc ttgcgccggc cctcaagagg      360

cgacgaggaa gcggccgcct ccctgcgccc cgcccctccg gctagctcgc tggctcccgg      420

ctcctcccga cgtctcctac ctcctcacgg ctcttcccgg cgctctcctg gctcccttct      480

gccccagctc cgtctcggcg gcggcgggca gttgcagtgg tgcagaatgg ctgacctcag      540

tcttgcagat gcattaacag aaccatctcc agacattgag ggagagataa agcgggactt      600

cattgccaca ctagaggcag aggcctttga tgatgttgtg ggagaaactg ttggaaaaac      660

agactatatt cctctcctgg atgttgatga gaaaaccggg aactcagagt caaagaagaa      720

accgtgctca gaaactagcc agattgaaga tactccatct tctaaaccaa cactcctagc      780

caatggtggt catggagtag aagggagcga tactacaggg tctccaactg aattccttga      840

agagaaaatg gcctaccagg aatacccaaa tagccagaac tggccagaag ataccaactt      900

ttgtttccaa cctgagcaag tggtcgatcc tatccagact gatcccttta agatgtacca      960

tgatgatgac ctggcagatt tggtctttcc ctccagtgcg acagctgata cttcaatatt     1020

tgcaggacaa aatgatccct tgaaagacag ttacggtatg tctccctgca acacagctgt     1080

tgtacctcag gggtggtctg tggaagcctt aaactctcca cactcagagt cctttgtttc     1140

cccagaggct gttgcagaac ctcctcagcc aacggcagtt cccttagagc tagccaagga     1200

gatagaaatg gcatcagaag agaggccacc agcacaagca ttggaaataa tgatgggact     1260

gaagactact gacatggcac catctaaaga aacagagatg gccctcgcca aggacatggc     1320

actagctaca aaaaccgagg tggcattggc taaagatatg gaatcaccca ccaaattaga     1380

tgtgacactg gccaaggaca tgcagccatc catggaatca gatatggccc tagtcaagga     1440

catggaacta cccacagaaa aagaagtggc cctggttaag gatgtcagat ggcccacaga     1500

aacagatgta tcttcagcca agaatgtggt actgcccaca gaaacagagg tagccccagc     1560

caaggatgtg acactgttga aagaaacaga gagggcatct cctataaaaa tggacttagc     1620

cccttccaag gacatgggac cacccaaaga aaacaagaaa gaaacagaga gggcatctcc     1680

tataaaaatg gacttggctc cttccaagga catgggacca cccaaagaaa acaagatagt     1740

cccagccaag gatttggtat tactctcaga aatagaggtg gcacaggcta atgacattat     1800

atcatccaca gaaatatcct ctgctgagaa ggtggctttg tcctcagaaa cagaggtagc     1860

cctggccagg gacatgacac tgcccccgga aaccaacgtg atcttgacca aggataaagc     1920

actaccttta gaagcagagg tggccccagt caaggacatg gctcaactcc cagaaacaga     1980

aatagccccg gccaaggatg tggctccgtc cacagtaaaa gaagtgggct tgttgaagga     2040

catgtctcca ctatcagaaa cagaaatggc tctgggcaag gatgtgactc cacctccaga     2100

aacagaagta gttctcatca agaacgtatg tctgcctcca gaaatggagg tggccctgac     2160

tgaggatcag gtcccagccc tcaaaacaga agcacccctg gctaaggatg gggttctgac     2220

cctggccaac aatgtgactc cagccaaaga tgttccacca ctctcagaaa cagaggcaac     2280

accagttcca attaaagaca tggaaattgc acaaacacaa aaaggaataa gtgaggattc     2340

ccatttagaa tctctgcagg atgtggggca gtcagctgca cctactttca tgatttcacc     2400

agaaaccgtc acaggaacgg ggaaaaagtg cagcttgccg gccgaggagg attctgtgtt     2460

agaaaaacta ggggaaagga aaccatgcaa cagtcaacct tctgagcttt cttcagagac     2520

ctcaggaata gccaggccag aagaaggaag gcctgtggtg agtgggacag gaaatgacat     2580

caccacccca ccgaacaagg agctcccacc aagcccagag aagaaaacaa agcctttggc     2640

caccactcaa cctgcaaaga cttcaacatc gaaagccaaa acacagccca cttctctccc     2700

taagcagcca gctcccacca ccattggtgg gttgaataaa aaacccatga gccttgcttc     2760

aggcttagtg ccagctgccc cacccaaacg ccctgccgtc gcctctgcca ggccttccat     2820

cttaccttca aaagacgtga agccaaagcc cattgcagat gcaaaggctc ctgagaagcg     2880

ggcctcacca tccaagccag cttctgcccc agcctccaga tctgggtcca agagcactca     2940

gactgttgca aaaaccacaa cagctgctgc tgttgcctca actggcccaa gcagtaggag     3000

cccctccacg ctcctgccca agaagcccac tgccattaag actgagggaa aacctgcaga     3060

agtcaagaag atgactgcaa agtctgtacc agctgacttg agtcgcccaa agagcacctc     3120

caccagttcc atgaagaaaa ccaccactct cagtgggaca gcccccgctg caggggtggt     3180

tcccagccga gtcaaggcca cacccatgcc ctcccggccc tccacaactc ctttcataga     3240

caagaagccc acctcggcca aacccagctc caccaccccc cggctcagcc gcctggccac     3300

caatacttct gctcctgatc tgaagaatgt ccgctccaag gttggctcca cggaaaacat     3360

caagcatcag cctggaggag gccgggccaa agtagagaaa aaaacagagg cagctgctac     3420

aacccgaaag cctgaatcta atgcagtcac taaaacagcc ggcccaattg caagtgcaca     3480

gaaacaacct gcggggaaag tccagatagt ctccaaaaaa gtgagctaca gccatattca     3540

gtccaagtgt ggttccaagg acaatattaa gcatgtccct ggaggtggta atgttcagat     3600

tcagaacaag aaagtggaca tctctaaggt ctcctccaag tgtgggtcta aggctaacat     3660

caagcacaag cctggtggag gagatgtcaa gattgaaagt cagaagttga acttcaagga     3720

gaaggcccag gccaaggtgg gatccctcga taatgtgggc cacctacctg caggaggtgc     3780

tgtgaagact gagggcggtg gcagcgaggc tcctctgtgt ccgggtcccc ctgctgggga     3840

ggagccggcc atctctgagg cagcgcctga agctggcgcc cccacttcag ccagtggcct     3900

caatggccac cccaccctgt cagggggtgg tgaccaaagg gaggcccaga ccttggacag     3960

ccagatccag gagacaagca tctaatgatg acattctggt ctcgtcttcc gtctcccccg     4020

tgttcccctc ttgtctcccc tgttcccctc tcccttccct cctcccatgt cactgcagat     4080

tgagacctac aggctgacgt tccgggcaaa tgccagggcc cgcaccgacc acggggccga     4140

cattgtctcc cgccccccac acttccctgg cggccccaac tcgggctccc gggtccttgg     4200

ccccctttcc cgggctgtcc actagaccag tgagcgcttg ggcgccgtgc tgggcagccc     4260

gctaggctcg ccttccctcc tgctttgcgt gcccggggca gcagcagccc tgccccacac     4320

ctcctctcac tccccagcct gggcccatct ccctgctttg gtcttgcccc atcactgcgc     4380

cactgctccg tggaggaggt tgggaggggg ttggggtggt tgaggctaag ttgggatcta     4440

ggagaggaga accagattct atcctcatct ttttttggtt ctttggtcca aacccaaaag     4500

aaactgacat gccctccctt ctccctggat ctacctggag ggaagagtgg aggtggattc     4560

cgagtggtga caggacgctg accgtggagc ttaagccact gcctctccct ctggtcccac     4620

aaatgggcgc ccccccctcc ccatgcaggt ggtgtcgggc ccttcttgct gccctgcccc     4680

aagttggggg tcagtgctgc ctgtccccat gcttaacata cccgcctagc tgctgtcaca     4740

tttttcttgt tttgtccttt tatttttttc taataaccta aaaactggca aaatagttct     4800

gcaggttgaa gccatgtcta catgaaagtc ctcagtaagt gttagaggga acagggcgga     4860

gatatcctta tgccaccccc gctggaggat gtgggcagct tagggccctg gaggcggtgc     4920

ggcagggaag aggggtgcag aggctgtggc tggtgagccg gtcaggcaca caaggggccc     4980

ttggagcgtg gactggttgg ttttgccatt ttgttgtgtg tatgctgctt ttcttttcta     5040

accaagaggc tggttttggc atctctgtcc cattccctgg gatctggtgg tcagccctag     5100

gataaaaagc cagggctgga gaacaagaaa gggccaggag atggaattcc ttcaggccgg     5160

cacccacacc ctaggacatg taagccctca tgtccaaggg agcctcatgc agatagtagg     5220

aaatcaggtc tggaaattta aaaataaaag gcatgagact aaggctatct gcttccctta     5280

tgccctgact ggagagggga gggaggagag gcaaggccca cagagggcat cccagctagg     5340

ccttgggatg gctgcagtga ggagaaatcc cgggaactgt attgacacaa agattcttat     5400

tgcacttgta ttttttgtat taaagtttgc atggtttcta ataaaggatt caaacataag     5460

tttgtagtga aatggcctgg gagattccaa gggcttctct ggagggggat tggctgcagt     5520

gtagatttgc ctctgaggag gctgccccag acttggcctc ctcatgcccc ctcctgacct     5580

ctgcccttct ctggtcctgg catccctgga gaaggtaggg gtcttgacct aagtttagat     5640

ttgatctcca tgtgcaggga ggctgtcctg ggcctgacag gtcctccccc tttctgaggt     5700

agcagtgcct tgtggaggtt tgacaccatg tccctagctc cccaagcaca caccaggaaa     5760

ctgcaggggc tcacggagga agtgctgcct gggccagggg gaccagcttt cctccgtaga     5820

gaccatgtgc agaacacttc tgctgtgcca agaacatgag ggagccagtg ttttgtcagc     5880

aggaagaaag ggcctgctgg gatgaaagtg ggaaggaaac agggttgcgt agtcaggaga     5940

cacctcaggg gcaacagcac aggcccagag tacctgctgc ctccactgcg tctgtcctgg     6000

ggtcatgagg atgctgaggt tgacgacagg ttccaggtcc tttcactcct ttggccaaag     6060

gttgggggta ggtggcccaa gtggcgtgct ctctaggtag acaacaggag tggtcagagt     6120

tccctcaaag gatcctccac tccagagcac ctgagaaggc cgggaccaga ggccctgtgt     6180

gatgtgtact ccgcagctgt ttggggtggg acatttctgt acttctcgat ttgcttatgg     6240

ctcagccatt acctgtgtca gtccatgatt ctgttgtaac agttttaaga gtaaataaat     6300

aaagctgcct gatgtcccat cacgcagaaa aaaaaaa                              6337


<210>  1687
<211>  4563
<212>  DNA
<213>  homo sapiens

<400>  1687
atggaggcca aggtccgccc gagccggcgc tcgcgcgcgc agcgggaccg tggccggcgc       60

cgggaggccg cccgcgacgc ccgcgcccag agtccgtcgt cgggcgacga gcccgagccc      120

agccccggca aggagaacgc gggcctccgc ggcgcgcccc cccgaggcgc cgcccccgcg      180

ccccgcaccg cgcgtccccc gcgccgccgc cgccgcgagt ccagctcgca ggaggaggag      240

gtcatcgacg gcttcgccat cgccagcttc agcaccctgg aggccctgga gaaggatatg      300

gccctgaagc cacatgagcg gaaggagaag tgggagcgtc gtctcatcaa gaagccccgg      360

gagtcggaaa cctgcccccc tgcggagccc agtgagaaca ggcggcccct ggaggcaggc      420

agccccgggc aggacctcga acccgcctgc gatggggcga gaaaggtccc actgcagccc      480

tccaagcaga tgaaggtcac cgtgtccaaa gggggcgacc gggacagtga cgacgacagc      540

gtcctcgaag ccaccagctc ccgggacccg ctcagcgata gctctgcgca tgcggtctcg      600

gggagaggct actcttgtga cagcgagagc ggcccggacg acaaggcatc cgtgggctct      660

gagaagctct ttgcgccggg aaccgataaa ggcccagcgc ttgagaagtc ggaggccaag      720

gccgggccgg tgcccaaggt gtcaggcctg gagcgcagcc gcgagctcag cgccgagagc      780

ttcctgccca ctgccagccc cgcgccccat gccgcgccct gcccggggcc cccgcccggc      840

tcccgcgcca atcccttggt gaagaaggaa ccccccgccc cgcaccgcca caccccgcag      900

ccgccacccc cgcagccccg cggcctgctc ccgacacacg tgcctgcatc cctgggcgcc      960

ttcgcgggcc acagccaggc ggcagccaac ggcctgcacg gcctcagcag gagcagcagc     1020

gcccccctgg gcctggggaa gcacgtgtcg ctgtcgccac acgggccggg cccccacctg     1080

tctacctcac acctggcgct ccggtcccag gcgcagcacc agctccacgc ggccatgttt     1140

gccgcacccc cgacactgcc cccgcccccg gcgctgccgg ccagcagcct ggtcctccca     1200

ggacacccgg ccgatcacga gctgctcagg caagagctga acacgcggtt tctggtgcag     1260

agcgccgagc ggcctggcgc ctccctgggc ccgggggctc tgctgcgggc ggagttccat     1320

cagcaccagc acacacacca gcacacgcac caacacacac accagcacca acacacattc     1380

gcccccttcc ccgcagggct gcccccgacg ccgcccgccg cacccccgcc gtttgacaag     1440

tatgcgccca agctggacag cccctacttc cgacattcca gcgtgagttt cttcccgtcc     1500

ttccctcctg ccatcccggg actgcccacc ctgctcccac accccggccc cttcgggtcc     1560

ctgcagggcg cttttcagcc taaggtgtct gacccgtacc gggcggtggt caaggtgagc     1620

acgtgttggg aaggcccgtg gcaagggagg actctggtgc ccccggggcg gcctcggggg     1680

gcccgtgaca gcaggagtct gcagaaaaca tgggtggggg tggcaccagc cccactgagc     1740

gcttccatcc tgtcgcagaa gccggggagg tggtgtgccg tgcacgtgca gatcgcctgg     1800

cagatctacc gtcaccagca gaagataaag gagatgcagc tggaccccca caagctggag     1860

gtgggtgcaa agctggacct gttcggcaga ccccctgccc cgggcgtgtt tgcaggcttc     1920

cactacccac aggacctggc ccggcccctc ttccccagca caggtgccgc ccatcctgcc     1980

tccaacccat ttggaccctc agcccatcct ggcagcttcc tgcccactgg ccccctgaca     2040

gaccctttca gcagaccgag cacctttggg ggcctgggca gcctgagcag ccacgccttt     2100

gggggcctgg gcagccatgc actggctccc ggtggcagca tctttgcccc caaggagggc     2160

tcctccgtgc acggcctgcc cagcccccat gaggcctgga accgactgca ccgggcaccg     2220

ccctccttcc cggctccgcc cccgtggccc aagtccgtgg acgcggagcg ggtgtcagcc     2280

ctgaccaacc atgaccgaga gccggacaat ggcaaggagg agcaggaacg ggacctcctg     2340

gagaagacgc gcctgctgag ccgggcctcg cccgccaccc ccgctggcca ccccgtcagc     2400

ggcctcctgc tccgggccca gagcgagctg ggccggtccg gggcccccgc ggagcgcgag     2460

gccgaacctc gggtcaagga gagccgctcc ccggccaagg aggaggccgc caagatgccc     2520

gcgcgcgcat ccccgcccca cagcaaggcg gcccctggag acgtgaaggt caaggaggag     2580

cgcggggagg acgaggcctc cgagcccccg gcgggcggcc tgcaccccgc gcccctgcag     2640

ctcggcctgg gccgcgagcg cctgggcgcg ccgggcttcg cgtgggagcc tttccgcggc     2700

ctggagctgc cacgtcgcgc cttccccgct gccgcccccg ccccgggctc cgccgccctc     2760

ttggagcccc cggagcgccc ctaccgcgac cgcgagcccc acggctacag ccccgagcgc     2820

ctgcgcgggg agctggagcg cgcgcgggcc ccgcacctgc cgcccgccgc ccccgccttg     2880

gacggcgcgc tgctgccctc gctgggagcc ctgcacttcc cgcgcctctc gcccgccgcg     2940

ctgcacaatg ggctcctggc gcggaccccg cccgccgccg ccgccctcgg cgcaccgccc     3000

cccctggtga cggcggccgg gccccccacg ccccccgggc cgccgcggag ccggactact     3060

ccgctggggg gcctcgggcc gggcgaggcg cgcgactact ccccgtcccg aaatcccccg     3120

gaggtggagg cgcggtagcc ccggggccgc agacgcctct ccgagcggag cgcaccgctg     3180

tccgtctctc catcagttcc tagaactcaa gcacagctcc cgccgatcct ggggcggcgc     3240

cgcctctcca cccgcagcct gcggaggcgg ggacttgggt gtcggctttt ctgagggtga     3300

tcttttgttt tccgagtttg ggattcggct gttgggaaaa aaaaatcgcg tttgtacctt     3360

ttccccccac agatgagaag tgtttgtaat ggatttgtat ttttcttaat tttatgctct     3420

ttagacgttt aaaagaacca aaaaagaaac ttttgcttct tcgttttcgg ttgggatttg     3480

cagtttaatg gcctcagatc cttctccaga tccccagggt ttctttgtct tatttatgga     3540

gaaaaaccgg tcactttgtc cagcgcactg tgaggccccc actcaggcca gccctggccc     3600

ccccttggta cttggaaccg aagttacaga ttatattaaa ataataatgt acaaaacttt     3660

gtttttttgc cttattatgc agaagtgtaa tttctttttt ggtttgtttt tttaaaagca     3720

aacgaaacgt gtaaatagtc tgttgatata aatatatgac gttactaaat tcttaatcta     3780

gatagacttt ataaaaaccg tttccagaaa cccctctggt tgtttgtcta acatggtcac     3840

aaaaacccag gcgctgctgg ctgtaaacat tatcagaagt ttaatggcag caactttcct     3900

tcaactatgc aagcgcttcc cggcggctct gctggttggg ggaggaaggt tccgccagcg     3960

acctcccagc ccctgggtcc gtggaggggt tgggtccccc agcagagccc ctgggccagc     4020

agaacagcac tcctgggcgg ctcctgtggg cttcaggact ggccggctcc agccgcaagg     4080

gcgatgctgt ggacgtttgt gtggatggtg cagtgttctt ggaatctgta gaccagatcg     4140

gtggaggtat agaagtgcaa gagtctaaag gctgatttta cacacacaca cacacacaca     4200

cacacacaca caaaatcact gctgtgtgtt ttcttccgcc tgaggcatca gcgtcacctc     4260

ggtgtggtcg tcgcctccca ggcccttggc ctggcctcct ctcagtttgg gttttgccct     4320

cacccacatg agccccccca tgccctgccc cccttgcggc cttttgtgtt ccccgatgtc     4380

tgggctgtgt ccctgccggg attcccagcc ttcggggtca gccgtcgagc cacttgcttt     4440

gctcagttct gtgtttcagc cacatttcca cggtggaccc tgtttgtttt aaatattctg     4500

ttcccatgtc aatcagtgac gataaataca gccttgattt ggatgaaaaa aaaaaaaaaa     4560

aaa                                                                   4563


<210>  1688
<211>  3543
<212>  DNA
<213>  homo sapiens

<400>  1688
ggagcgcggg gagggcgagg ggaggaggag gcgcccgcct ggttccctgc aaagcggcct       60

tatttatctg ggcacagcct cagcctcccc ggtgggaggc ttggggcggc cgatcctctc      120

ccaccgggga gctcctttcc gtgcgctgcc gagggggccc ggccaggacg ggacgcgggg      180

cgcagggcgc ggccgggccc tgccggccag tccagcaccc cggcggcccc cgcgcgccga      240

cgcccatgcc gggctcccca tgacgggagg tcgcccggcg gacagcgtgg catgagccag      300

gagcccgggc cgagagcgtg ccaggaagat gtcgagcccg ggcatcgacg gcgaccccaa      360

gcctccatgc ttgcctcgaa acggtctggt gaagctgccg ggccagccca acggcctggg      420

tgcggccagc atcaccaagg gcacgccagc caccaagaac cgcccctgcc agccaccacc      480

cccacccacc ctcccaccac ccagcctggc tgctccactg tcccgggctg ccctggctgg      540

gggcccgtgc accccggcag gtggaccagc ctcagccttg gcacctgggc acccagcgga      600

gcggccgccg ctggccacgg acgagaagat cctcaatggg ctcttctggt atttctcggc      660

ctgcgagaag tgtgtgctgg cccaggtgtg caaggcctgg cggcgcgtgc tgtaccagcc      720

caagttctgg gcaggcctca cgccggtgct gcatgccaag gagctctaca acgtgctgcc      780

tggtggcgag aaggagttcg tgaacctgca gggttttgcc gccagaggct tcgagggctt      840

ctgcctggtt ggcgtctccg acctggacat ctgtgagttc attgacaact atgcgctctc      900

caagaagggt gtcaaagcca tgagcctcaa gcgctccacc atcacggacg caggcctcga      960

ggttatgctt gaacagatgc agggcgtggt gcgtctggag ctgtcgggct gcaacgactt     1020

caccgaggcc gggctgtggt ccagcctgag cgcgcgcatc acctcgctga gcgtgagtga     1080

ctgcatcaac gtggccgacg acgccatcgc ggccatctcg cagctgctgc ccaacctggc     1140

ggagctgagc ctgcaggcct accacgtgac ggacacggcg ctggcctact tcacggcgcg     1200

ccagggccac agcacgcaca cgctgcgcct gctctcctgc tgggagatca ccaaccacgg     1260

cgtggtcaac gtggtgcaca gcctgcccaa cctcaccgcg ctcagcctct cgggctgctc     1320

caaggtcacc gacgacggcg tggagctcgt ggccgagaac ctgcgcaagc tgcgcagcct     1380

tgacctctcg tggtgcccac gcatcaccga catggcgctg gagtacgtgg cctgcgacct     1440

gcaccgccta gaggagctcg tgctcgacag gtgtgtacgc atcacggaca ctggcctcag     1500

ctatctgtcc accatgtcgt ccctccgcag cctctacctg cgatggtgct gccaggtgca     1560

agacttcggg ctgaagcacc tcctggccct ggggagtttg cgcctcctgt ctctggcagg     1620

ctgcccgctg ctcaccacca ccgggctgtc gggcctggtg cagctgcagg agctggagga     1680

gctggagctg accaactgcc ccggggccac ccccgagctc ttcaagtatt tctcgcagca     1740

cctgccccgc tgcctcgtca ttgagtagcg cgaggccccc gccccggtcg cgggaacccg     1800

gccatgacct gggcgggggc gcggggcgcc gccgagcccc ctcttcccgc cttgcgctcg     1860

ggggagcccc cgcgcccccg gcccagcgcg ggaggcgggg cgagccgagg gaaagcccct     1920

ccccgacctt cggtccctcc gccctcccag ccccgccccg ggcagggggg cggcgggtgg     1980

gcccgcccca cgcacgcacg cacactcggg gactttgtgc atgcccctcg tgcccgcact     2040

gcacgccgcc ctccgccacg ccacagccac agccgccgcc atcactcgct cgccctcccg     2100

cttggggggc ggggctcggt ccttgggggg gctttgagct ctccagactg tgcccttacc     2160

gccttccccg ccacacccgc tctgtcttcc cactgtcccc cccatcccgg gcagggccca     2220

gtgggattga gggggctggg tcccccagga cacgggccca gaagagcccc acgggcttcc     2280

tgcatcttcc accgcaccat acctggagcc ctccgagggg tgtcagggga aacaggccac     2340

cgccaaagcc atggcccgcc gccgagagcc caggccccac ccgcacctcc tcacccatcc     2400

agcctgaccc acgcggcctc tcctcctcct tgccgctgtg tggggcagtc ccctgtccgc     2460

cccaaaaccc ggccttggtc cctggccagg ctgagagaat tgggcaggga gagggcggaa     2520

gggctggcga tcgcttggag tcattaacgt gatcccagct gactccggtc ggcctcaacc     2580

caggggtggc gcaggcacct tgcaagcctc gagctgtagc caccctcagg cctgggaaga     2640

ggcctgggcc gacctcacac ctcagccctt gcacccggcc gggctcagtt caggcctggg     2700

caccgagctt caccctgggt gggtctcctc aggtggagtc tgcagagtgg acccagccaa     2760

gggtcagggt cagcactggg tcagcgactc caatcttcca gtggccagca caccctagac     2820

accccgagga gggagggctc ctttctagcc tgccccccca cccccacttc acccctcccc     2880

agcttcccaa acttctgtct gcccaaatgg gctctgaccg tgctctgtcg gcccgagaca     2940

tttggaagtc ctgggggatg ctggcaaatc tcagctgttg ctgaggaggg ggctgggacc     3000

ccttcccatc ccaaccttga gccccaggag ataccgcgcc cacacccaat cttgggacac     3060

tccctatctg gttggaagag agtaaccagt ttccagagag ccagagagtg agagagagaa     3120

agagagtgag agagagagag aaagagagag agagatgctg ttgaatcaga aacagatcaa     3180

cagcccaaag attttcctgt ccctggagtg ccagccccag gaagctccag ggctgagtgg     3240

tcaggagcca gtttctccag cccctcctcc ccacaacccc tagtggggag gggcagctgt     3300

ccatttgccc aaagtattaa tgcaactgaa gctgtgatat ttccaacgac tgtaggagga     3360

aaaattaagg ggagagagga aaacaaaacc aaccaacccc taaaatcatt ttcttattgt     3420

acataacgac ctcattctcc tgtatatgcg gaagatataa ccttatattt ggtaagtgtt     3480

tcttgtgcta ttttatcacg tgacctgttt ataaaaatat atattaaaaa agttgtaaaa     3540

aca                                                                   3543


<210>  1689
<211>  3543
<212>  DNA
<213>  homo sapiens

<400>  1689
ggagcgcggg gagggcgagg ggaggaggag gcgcccgcct ggttccctgc aaagcggcct       60

tatttatctg ggcacagcct cagcctcccc ggtgggaggc ttggggcggc cgatcctctc      120

ccaccgggga gctcctttcc gtgcgctgcc gagggggccc ggccaggacg ggacgcgggg      180

cgcagggcgc ggccgggccc tgccggccag tccagcaccc cggcggcccc cgcgcgccga      240

cgcccatgcc gggctcccca tgacgggagg tcgcccggcg gacagcgtgg catgagccag      300

gagcccgggc cgagagcgtg ccaggaagat gtcgagcccg ggcatcgacg gcgaccccaa      360

gcctccatgc ttgcctcgaa acggtctggt gaagctgccg ggccagccca acggcctggg      420

tgcggccagc atcaccaagg gcacgccagc caccaagaac cgcccctgcc agccaccacc      480

cccacccacc ctcccaccac ccagcctggc tgctccactg tcccgggctg ccctggctgg      540

gggcccgtgc accccggcag gtggaccagc ctcagccttg gcacctgggc acccagcgga      600

gcggccgccg ctggccacgg acgagaagat cctcaatggg ctcttctggt atttctcggc      660

ctgcgagaag tgtgtgctgg cccaggtgtg caaggcctgg cggcgcgtgc tgtaccagcc      720

caagttctgg gcaggcctca cgccggtgct gcatgccaag gagctctaca acgtgctgcc      780

tggtggcgag aaggagttcg tgaacctgca gggttttgcc gccagaggct tcgagggctt      840

ctgcctggtt ggcgtctccg acctggacat ctgtgagttc attgacaact atgcgctctc      900

caagaagggt gtcaaagcca tgagcctcaa gcgctccacc atcacggacg caggcctcga      960

ggttatgctt gaacagatgc agggcgtggt gcgtctggag ctgtcgggct gcaacgactt     1020

caccgaggcc gggctgtggt ccagcctgag cgcgcgcatc acctcgctga gcgtgagtga     1080

ctgcatcaac gtggccgacg acgccatcgc ggccatctcg cagctgctgc ccaacctggc     1140

ggagctgagc ctgcaggcct accacgtgac ggacacggcg ctggcctact tcacggcgcg     1200

ccagggccac agcacgcaca cgctgcgcct gctctcctgc tgggagatca ccaaccacgg     1260

cgtggtcaac gtggtgcaca gcctgcccaa cctcaccgcg ctcagcctct cgggctgctc     1320

caaggtcacc gacgacggcg tggagctcgt ggccgagaac ctgcgcaagc tgcgcagcct     1380

tgacctctcg tggtgcccac gcatcaccga catggcgctg gagtacgtgg cctgcgacct     1440

gcaccgccta gaggagctcg tgctcgacag gtgtgtacgc atcacggaca ctggcctcag     1500

ctatctgtcc accatgtcgt ccctccgcag cctctacctg cgatggtgct gccaggtgca     1560

agacttcggg ctgaagcacc tcctggccct ggggagtttg cgcctcctgt ctctggcagg     1620

ctgcccgctg ctcaccacca ccgggctgtc gggcctggtg cagctgcagg agctggagga     1680

gctggagctg accaactgcc ccggggccac ccccgagctc ttcaagtatt tctcgcagca     1740

cctgccccgc tgcctcgtca ttgagtagcg cgaggccccc gccccggtcg cgggaacccg     1800

gccatgacct gggcgggggc gcggggcgcc gccgagcccc ctcttcccgc cttgcgctcg     1860

ggggagcccc cgcgcccccg gcccagcgcg ggaggcgggg cgagccgagg gaaagcccct     1920

ccccgacctt cggtccctcc gccctcccag ccccgccccg ggcagggggg cggcgggtgg     1980

gcccgcccca cgcacgcacg cacactcggg gactttgtgc atgcccctcg tgcccgcact     2040

gcacgccgcc ctccgccacg ccacagccac agccgccgcc atcactcgct cgccctcccg     2100

cttggggggc ggggctcggt ccttgggggg gctttgagct ctccagactg tgcccttacc     2160

gccttccccg ccacacccgc tctgtcttcc cactgtcccc cccatcccgg gcagggccca     2220

gtgggattga gggggctggg tcccccagga cacgggccca gaagagcccc acgggcttcc     2280

tgcatcttcc accgcaccat acctggagcc ctccgagggg tgtcagggga aacaggccac     2340

cgccaaagcc atggcccgcc gccgagagcc caggccccac ccgcacctcc tcacccatcc     2400

agcctgaccc acgcggcctc tcctcctcct tgccgctgtg tggggcagtc ccctgtccgc     2460

cccaaaaccc ggccttggtc cctggccagg ctgagagaat tgggcaggga gagggcggaa     2520

gggctggcga tcgcttggag tcattaacgt gatcccagct gactccggtc ggcctcaacc     2580

caggggtggc gcaggcacct tgcaagcctc gagctgtagc caccctcagg cctgggaaga     2640

ggcctgggcc gacctcacac ctcagccctt gcacccggcc gggctcagtt caggcctggg     2700

caccgagctt caccctgggt gggtctcctc aggtggagtc tgcagagtgg acccagccaa     2760

gggtcagggt cagcactggg tcagcgactc caatcttcca gtggccagca caccctagac     2820

accccgagga gggagggctc ctttctagcc tgccccccca cccccacttc acccctcccc     2880

agcttcccaa acttctgtct gcccaaatgg gctctgaccg tgctctgtcg gcccgagaca     2940

tttggaagtc ctgggggatg ctggcaaatc tcagctgttg ctgaggaggg ggctgggacc     3000

ccttcccatc ccaaccttga gccccaggag ataccgcgcc cacacccaat cttgggacac     3060

tccctatctg gttggaagag agtaaccagt ttccagagag ccagagagtg agagagagaa     3120

agagagtgag agagagagag aaagagagag agagatgctg ttgaatcaga aacagatcaa     3180

cagcccaaag attttcctgt ccctggagtg ccagccccag gaagctccag ggctgagtgg     3240

tcaggagcca gtttctccag cccctcctcc ccacaacccc tagtggggag gggcagctgt     3300

ccatttgccc aaagtattaa tgcaactgaa gctgtgatat ttccaacgac tgtaggagga     3360

aaaattaagg ggagagagga aaacaaaacc aaccaacccc taaaatcatt ttcttattgt     3420

acataacgac ctcattctcc tgtatatgcg gaagatataa ccttatattt ggtaagtgtt     3480

tcttgtgcta ttttatcacg tgacctgttt ataaaaatat atattaaaaa agttgtaaaa     3540

aca                                                                   3543


<210>  1690
<211>  1362
<212>  DNA
<213>  homo sapiens

<400>  1690
tttatagacg gtgattgggc tgctggaagc tgggaggggt gagggactgg agggagtcgg       60

agaaaaagct gacctaatga aactgtggca acgtcagcgc ttgaggcttg aagagggaga      120

caagctaaaa gaggatatcc agttgtttca tgatggcatt tgcacctcca aaaaacacag      180

atggtcccaa aatgcagaca aagatgagca cctggacacc cctaaaccat cagctattga      240

atgaccgggt atttgaagaa agaagagccc tgcttggcaa atggtttgac aaatggacag      300

actctcaaag aagaagaatc ctcacaggcc tgttggagcg ctgctcgctg tcccagcaaa      360

agttctgctg tcgaaagctt caagagaaaa ttccagcaga agccctggac tttacaacca      420

agcttccaag ggtgttatct ttatacatct tttctttcct ggaccctcgg agcctttgtc      480

gttgtgcaca ggtgtgctgg cattggaaga accttgctga gctggaccag ctctggatgc      540

tgaaatgttt acggtttaac tggtacatca atttctctcc aactcccttt gagcagggga      600

tctggaagaa gcactatatt caaatggtga aagaacttca tattaccaag cctaagacac      660

ccccaaagga tggatttgta atcgctgacg ttcaactagt tacaagcaat tctccagagg      720

aaaaacagtc ccctttatca gcttttcggt cctcttcctc tttaagaaag aagaataact      780

caggggagaa agcacttcca ccctggcgat cttctgataa gcacccaaca gatatcattc      840

gttttaatta cctagacaac cgtgacccca tggagactgt ccagcaagga agaagaaaaa      900

gaaaccaaat gaccccagac ttcagccgac agtcacatga taagaaaaat aaattgcagg      960

acagaactag gctaagaaaa gcacaatcaa tgatgtcgag gagaaatccc ttcccactat     1020

gtccctaagt gccagctctc ccctaaaagt tccagctcat ctcgcctggc ctccccctga     1080

gtcagtggga ctcccagaca ctgccaccac agctgaaatt ctcatgcagc atcctcacag     1140

gcaccctggg ccccaagcat gactcatcca ggttccagag ccaaagtgga ctgaacatgg     1200

aaagactttt attatagaaa tgacaagatg ctttgcacag tggagagctg aatttacttg     1260

gctcccatta gaaactcttt cagcttaagt acttattgtg gtagtgagtc ctacggtatt     1320

tcagtaaaaa ggaattcatg gcataaaaaa aaaaaaaaaa aa                        1362


<210>  1691
<211>  5965
<212>  DNA
<213>  homo sapiens

<400>  1691
ggtaacagtt cgcggcagtt cgcgcgggag cggggcgcct gggtggatgg gcgcttgggc       60

gcctgggctg ccggacggtg ggaacggaag tcgctgtggg acgctgagga agccaggatg      120

gcgactccga gcaagaagac gtcaactcca agcccccagc cttccaagag agctctcccg      180

agagaccctt cgtcggaggt cccgagcaag aggaagaatt cggccccgca gctgccgctg      240

ttgcagtcgt ccgggccttt cgtggaaggc tctatcgtcc gcatctcgat ggagaacttc      300

ctaacatatg atatttgtga agtatctcct ggaccccact tgaatatgat cgttggagcc      360

aatggaacag ggaagtcgag cattgtgtgt gccatttgcc ttggtttagc tggaaaacct      420

gctttcatgg gacgagcaga taaggttggg ttttttgtga agagaggatg ttctagaggc      480

atggttgaaa ttgaattgtt cagggcttct ggaaatcttg taatcacccg tgagattgat      540

gtggcaaaaa atcagtcctt ttggttcatc aacaaaaaat ctacaaccca gaaaatagtg      600

gaagagaaag ttgcagcctt aaatattcaa gtggggaatc tttgccagtt tctccctcag      660

gacaaagttg gagaatttgc taaactcagc aaaattgaac tcctcgaagc cactgaaaag      720

tcaattggtc ccccagaaat gcacaaatat cactgtgaac tcaaaaactt aagggagaaa      780

gaaaaacagc tcgagacctc atgcaaagag aaaactgagt atctacagaa aatggttcag      840

aggaatgaaa gatataaaca agatgtggag aggttctatg aacggaagcg acatttagat      900

ttaattgaga tgcttgaagc aaaaaggcca tgggtggaat atgaaaatgt tcgtcaggaa      960

tatgaagaag taaaactagt tcgtgaccga gtgaaggaag aggtcagaaa acttaaagaa     1020

gggcagattc ctgtaacatg tcgaattgaa gaaatggaaa acgagcgtca caatttggag     1080

gctcgaatca aagaaaaggc aacagatatt aaggaggcat ctcaaaaatg caaacagaag     1140

caagatgtta tagaaaggaa agataaacat attgaggaac ttcagcaggc tttaatagta     1200

aagcaaaatg aagagcttga ccgacagagg agaataggta atacccgcaa aatgatagag     1260

gatttgcaaa atgaactaaa gaccacggaa aactgcgaga atcttcagcc ccagattgat     1320

gccattacaa atgatctgag acggattcag gatgaaaagg cattatgtga aggcgaaata     1380

attgataagc gaagagagag ggaaactcta gagaaggaga aaaagagtgt ggacgatcat     1440

attgtacgtt ttgacaatct tatgaatcag aaggaagata agctaagaca gagattccgt     1500

gacacgtatg atgctgtttt atggctaaga aataacagag acaaatttaa acaaagagtc     1560

tgtgagccca taatgctcac gatcaatatg aaagataata aaaatgccaa atatattgaa     1620

aatcatattc catcaaatga cttaagagcc tttgtatttg aaagtcaaga agatatggag     1680

gttttcctca aagaggttcg tgacaataaa aaattaagag taaatgctgt tattgctccc     1740

aagagttcat atgcagacaa agcaccttca agatctttga atgaacttaa acaatacgga     1800

tttttctctt atttgagaga attatttgat gcacctgatc ctgtaatgag ttacctttgc     1860

tgtcagtatc atattcatga agttcctgta ggaactgaaa agaccagaga aagaattgaa     1920

cgggtaatac aagaaacccg attaaaacag atttatacag cagaagaaaa gtatgtggtg     1980

aaaacttctt tttattcaaa caaagttatt tctagtaaca catctctaaa agtagcgcag     2040

tttctcactg tcactgtgga cctagagcag agaagacact tagaagaaca gctaaaggaa     2100

attcatagaa aattgcaagc agtggattca gggttgattg ccttacgtga aacaagcaaa     2160

catctggagc acaaagacaa tgaacttaga caaaagaaga aggagcttct tgagagaaaa     2220

accaagaaaa gacaactgga acaaaaaatc agttccaaac taggaagttt aaagctgatg     2280

gaacaggata cttgcaatct tgaagaggaa gagcgaaaag caagtaccaa aatcaaagaa     2340

ataaatgttc aaaaagcgaa acttgttacc gaattaacaa acctaataaa gatttgtact     2400

tctttgcata tacaaaaagt agatttaatt ctccaaaata ctacagtgat ctctgagaag     2460

aacaaattag aatcagatta tatggccgca tcttcacaac tccgtcttac agagcaacat     2520

ttcattgaat tggatgaaaa tagacagaga ttattgcaga aatgcaagga acttatgaaa     2580

agagctaggc aagtatgtaa cctgggtgca gagcagactc ttcctcaaga ataccagaca     2640

caagtaccca ccattccaaa tggacacaac tcctcactcc ccatggtttt ccaagacctt     2700

ccaaacacat tggatgaaat tgatgcttta ttaactgaag aaagatcaag agcttcctgc     2760

ttcacgggac tgaatcctac aattgttcag gaatatacaa aaagagaaga agaaatagaa     2820

cagttaactg aggaactaaa gggaaagaaa gttgaactag atcaatacag ggaaaacatt     2880

tcacaggtaa aagaaaggtg gcttaatcct ttaaaagagc tggtagaaaa aattaatgaa     2940

aaattcagca atttttttag ttccatgcag tgtgctggtg aagttgatct ccatacagaa     3000

aatgaggaag attatgataa atatggaatt cgaattagag tcaaatttcg aagtagtact     3060

caactgcatg aattaactcc tcatcatcaa agtggaggtg aaagaagtgt ttctaccatg     3120

ttatacttga tggcacttca ggagctaaat agatgtccat tcagagtagt tgatgaaatc     3180

aatcagggaa tggacccaat caatgaacgg agagtgtttg aaatggttgt aaatactgcc     3240

tgtaaagaaa atacatctca atactttttc ataacaccaa agctcctgca aaatcttcct     3300

tattctgaaa agatgacagt tttgtttgtc tacaatggcc ctcatatgct ggaaccaaac     3360

acatggaatt taaaggcttt ccaaaggcgg cggcgccgta ttacattcac tcaaccttct     3420

taataaaagt aaagagaggg aacttgggaa ttttttttgt taaattctgt ttataagtat     3480

ggctcaactg aataaaagga gattcactaa aacgaaaagc agttattttt ggaaacctgc     3540

ttttaaatac aaataggttg ataatggaaa ctataatgac ctttccaaaa tagcagctgg     3600

tagtaaaagt taagtcttct tcagtcttgg ttgaacttga gttcttggca ctctgaccat     3660

gagtcattca gttctcatgt taaaatgtac ttaatattac aaatcaaagg tacagtggaa     3720

gaagggttaa tcacaagaag ttacttatat ggtagccctg agctttaatt gcagagtaac     3780

tttaattact tttagagcct aaagatgact ctagagccta agtcctagtt tctcccaatg     3840

ttatatttaa ttttaaaaaa ttgatatgaa aatgtctaat gtatagtaat aatttatgac     3900

agatctagtc atttcttcct attaaaaaag attaccttat ctccagtagg aaatggaatt     3960

ttatgggcct ttaaaagaaa gttttatgaa acttgatgct ataattttat tggtatttca     4020

aggggaaaaa agcactgggg ttcaaaaatg gtagcagaac tgctttgaaa tgctgcaagg     4080

tggccactag atgatgcaaa atacaaccaa aagattgact gagaataaaa ttaggtgaca     4140

agggttttta aagaataacc ttttaaagtg tgggggcagg ggttgctttt ttttatttta     4200

tttaaagtca attatatttt acatcttaca tttctaaaag cattttataa ttatttttag     4260

taagattttt cttaaaattt catatactgg tttctacaat ttatatttga aatttctcag     4320

tgttatgtaa agagtgatgg aaaagcattg atttctttaa aaccgtaatg tttttagaac     4380

ttaagcctat agggcctttc ttacaatgtt gatgtaccca ttatcttaga aaatctagtt     4440

taaactgttt tctttcaccg caaaagaatt aaatgggaaa atcatttgtt tatctctaag     4500

ttatactaat tagtagaacc aaacaaatta tcttctttta aaaaataaat cttataggaa     4560

aatagacagt ccaaagtcat gtctttgaac agtggattgg atctgtgcca gtaatgacaa     4620

aattattttt ttgacttgct tgcctgaata aattgaagaa ttgctttcag tttgggtttt     4680

gtatattctt aagtagccat tgaaatttat attcttaact aggtcaaaaa ataatgagcc     4740

ataagtttat gtcctctcac ttagacattt tctctttaaa aaggtatttt cttctttata     4800

aacattttaa aagagccttc ccttcttaaa ctaactccag tgcatgaagt gtgaaaatat     4860

tttaaaatga catttttact aatatgagca agtcatgtaa acattgaaga acttggtaac     4920

atattagtaa atggatatta ccaaatgttt tcatcgttaa ttactttgcg ttccaccaaa     4980

atatctttac taaaatgtgc ttggtgtagt ttgtttattg tctaaattag taccagtcat     5040

cttatttctg caaaatgagt atcaatgtga aaaagacacg tgaagattaa gcatgtttga     5100

aaataaaatg gtcaattaca tttcaattta cataggccaa caactgttcc atactttgtt     5160

tgtaaacatt taatttctct actggacaaa attaatattt ggctttacat tgaattttga     5220

gctgtgaaga ataaattatg tatcatttta gcatattaaa cagtagtaag tctagcacat     5280

agtctcagcc acttaaaaca aaagtttttt tgtttgtttg tttgtttgtt tttttgagat     5340

ggagtctcac tctgttgccc aggctggagt gcagtggcgt gatctcggct tactgcaacc     5400

tccgcctccc gggttcaagc gattctcctg cctcagcctc ccaagtaact gggacaacag     5460

gcgcgtccca ccacacccag ctaatttttt atacttttag tagagatggg gtttcagcat     5520

attggccagg ctggtctcga actcctgacc ttgtgatcca cccgcctcgg cctcccaaag     5580

tgctgggatt ataggcgtga gcccctgcac ccggccaaaa gttgattttt aattacataa     5640

aaatcgtaaa aacttctagt aaaaacttga tttggtgaat acagttatat ttaaaaacct     5700

taaggtgaca agcattttct atgcctaaat cttcattggt ttgcctggaa agagtctctg     5760

ttaaaagatt ttccatattc aaagtaaaag gaaagatttc ttgctttcta attgtctttt     5820

ggacacatgc ctattttctt tgaggtataa acctttagat gtgaaaaatg taatttcatt     5880

ctgctattgt gtgtgcttgt gtgtgtgtaa ttgaaaaaac tgggaaatcc tgctttgttg     5940

gtaataaatc aatattttta tattc                                           5965


<210>  1692
<211>  5965
<212>  DNA
<213>  homo sapiens

<400>  1692
ggtaacagtt cgcggcagtt cgcgcgggag cggggcgcct gggtggatgg gcgcttgggc       60

gcctgggctg ccggacggtg ggaacggaag tcgctgtggg acgctgagga agccaggatg      120

gcgactccga gcaagaagac gtcaactcca agcccccagc cttccaagag agctctcccg      180

agagaccctt cgtcggaggt cccgagcaag aggaagaatt cggccccgca gctgccgctg      240

ttgcagtcgt ccgggccttt cgtggaaggc tctatcgtcc gcatctcgat ggagaacttc      300

ctaacatatg atatttgtga agtatctcct ggaccccact tgaatatgat cgttggagcc      360

aatggaacag ggaagtcgag cattgtgtgt gccatttgcc ttggtttagc tggaaaacct      420

gctttcatgg gacgagcaga taaggttggg ttttttgtga agagaggatg ttctagaggc      480

atggttgaaa ttgaattgtt cagggcttct ggaaatcttg taatcacccg tgagattgat      540

gtggcaaaaa atcagtcctt ttggttcatc aacaaaaaat ctacaaccca gaaaatagtg      600

gaagagaaag ttgcagcctt aaatattcaa gtggggaatc tttgccagtt tctccctcag      660

gacaaagttg gagaatttgc taaactcagc aaaattgaac tcctcgaagc cactgaaaag      720

tcaattggtc ccccagaaat gcacaaatat cactgtgaac tcaaaaactt aagggagaaa      780

gaaaaacagc tcgagacctc atgcaaagag aaaactgagt atctacagaa aatggttcag      840

aggaatgaaa gatataaaca agatgtggag aggttctatg aacggaagcg acatttagat      900

ttaattgaga tgcttgaagc aaaaaggcca tgggtggaat atgaaaatgt tcgtcaggaa      960

tatgaagaag taaaactagt tcgtgaccga gtgaaggaag aggtcagaaa acttaaagaa     1020

gggcagattc ctgtaacatg tcgaattgaa gaaatggaaa acgagcgtca caatttggag     1080

gctcgaatca aagaaaaggc aacagatatt aaggaggcat ctcaaaaatg caaacagaag     1140

caagatgtta tagaaaggaa agataaacat attgaggaac ttcagcaggc tttaatagta     1200

aagcaaaatg aagagcttga ccgacagagg agaataggta atacccgcaa aatgatagag     1260

gatttgcaaa atgaactaaa gaccacggaa aactgcgaga atcttcagcc ccagattgat     1320

gccattacaa atgatctgag acggattcag gatgaaaagg cattatgtga aggcgaaata     1380

attgataagc gaagagagag ggaaactcta gagaaggaga aaaagagtgt ggacgatcat     1440

attgtacgtt ttgacaatct tatgaatcag aaggaagata agctaagaca gagattccgt     1500

gacacgtatg atgctgtttt atggctaaga aataacagag acaaatttaa acaaagagtc     1560

tgtgagccca taatgctcac gatcaatatg aaagataata aaaatgccaa atatattgaa     1620

aatcatattc catcaaatga cttaagagcc tttgtatttg aaagtcaaga agatatggag     1680

gttttcctca aagaggttcg tgacaataaa aaattaagag taaatgctgt tattgctccc     1740

aagagttcat atgcagacaa agcaccttca agatctttga atgaacttaa acaatacgga     1800

tttttctctt atttgagaga attatttgat gcacctgatc ctgtaatgag ttacctttgc     1860

tgtcagtatc atattcatga agttcctgta ggaactgaaa agaccagaga aagaattgaa     1920

cgggtaatac aagaaacccg attaaaacag atttatacag cagaagaaaa gtatgtggtg     1980

aaaacttctt tttattcaaa caaagttatt tctagtaaca catctctaaa agtagcgcag     2040

tttctcactg tcactgtgga cctagagcag agaagacact tagaagaaca gctaaaggaa     2100

attcatagaa aattgcaagc agtggattca gggttgattg ccttacgtga aacaagcaaa     2160

catctggagc acaaagacaa tgaacttaga caaaagaaga aggagcttct tgagagaaaa     2220

accaagaaaa gacaactgga acaaaaaatc agttccaaac taggaagttt aaagctgatg     2280

gaacaggata cttgcaatct tgaagaggaa gagcgaaaag caagtaccaa aatcaaagaa     2340

ataaatgttc aaaaagcgaa acttgttacc gaattaacaa acctaataaa gatttgtact     2400

tctttgcata tacaaaaagt agatttaatt ctccaaaata ctacagtgat ctctgagaag     2460

aacaaattag aatcagatta tatggccgca tcttcacaac tccgtcttac agagcaacat     2520

ttcattgaat tggatgaaaa tagacagaga ttattgcaga aatgcaagga acttatgaaa     2580

agagctaggc aagtatgtaa cctgggtgca gagcagactc ttcctcaaga ataccagaca     2640

caagtaccca ccattccaaa tggacacaac tcctcactcc ccatggtttt ccaagacctt     2700

ccaaacacat tggatgaaat tgatgcttta ttaactgaag aaagatcaag agcttcctgc     2760

ttcacgggac tgaatcctac aattgttcag gaatatacaa aaagagaaga agaaatagaa     2820

cagttaactg aggaactaaa gggaaagaaa gttgaactag atcaatacag ggaaaacatt     2880

tcacaggtaa aagaaaggtg gcttaatcct ttaaaagagc tggtagaaaa aattaatgaa     2940

aaattcagca atttttttag ttccatgcag tgtgctggtg aagttgatct ccatacagaa     3000

aatgaggaag attatgataa atatggaatt cgaattagag tcaaatttcg aagtagtact     3060

caactgcatg aattaactcc tcatcatcaa agtggaggtg aaagaagtgt ttctaccatg     3120

ttatacttga tggcacttca ggagctaaat agatgtccat tcagagtagt tgatgaaatc     3180

aatcagggaa tggacccaat caatgaacgg agagtgtttg aaatggttgt aaatactgcc     3240

tgtaaagaaa atacatctca atactttttc ataacaccaa agctcctgca aaatcttcct     3300

tattctgaaa agatgacagt tttgtttgtc tacaatggcc ctcatatgct ggaaccaaac     3360

acatggaatt taaaggcttt ccaaaggcgg cggcgccgta ttacattcac tcaaccttct     3420

taataaaagt aaagagaggg aacttgggaa ttttttttgt taaattctgt ttataagtat     3480

ggctcaactg aataaaagga gattcactaa aacgaaaagc agttattttt ggaaacctgc     3540

ttttaaatac aaataggttg ataatggaaa ctataatgac ctttccaaaa tagcagctgg     3600

tagtaaaagt taagtcttct tcagtcttgg ttgaacttga gttcttggca ctctgaccat     3660

gagtcattca gttctcatgt taaaatgtac ttaatattac aaatcaaagg tacagtggaa     3720

gaagggttaa tcacaagaag ttacttatat ggtagccctg agctttaatt gcagagtaac     3780

tttaattact tttagagcct aaagatgact ctagagccta agtcctagtt tctcccaatg     3840

ttatatttaa ttttaaaaaa ttgatatgaa aatgtctaat gtatagtaat aatttatgac     3900

agatctagtc atttcttcct attaaaaaag attaccttat ctccagtagg aaatggaatt     3960

ttatgggcct ttaaaagaaa gttttatgaa acttgatgct ataattttat tggtatttca     4020

aggggaaaaa agcactgggg ttcaaaaatg gtagcagaac tgctttgaaa tgctgcaagg     4080

tggccactag atgatgcaaa atacaaccaa aagattgact gagaataaaa ttaggtgaca     4140

agggttttta aagaataacc ttttaaagtg tgggggcagg ggttgctttt ttttatttta     4200

tttaaagtca attatatttt acatcttaca tttctaaaag cattttataa ttatttttag     4260

taagattttt cttaaaattt catatactgg tttctacaat ttatatttga aatttctcag     4320

tgttatgtaa agagtgatgg aaaagcattg atttctttaa aaccgtaatg tttttagaac     4380

ttaagcctat agggcctttc ttacaatgtt gatgtaccca ttatcttaga aaatctagtt     4440

taaactgttt tctttcaccg caaaagaatt aaatgggaaa atcatttgtt tatctctaag     4500

ttatactaat tagtagaacc aaacaaatta tcttctttta aaaaataaat cttataggaa     4560

aatagacagt ccaaagtcat gtctttgaac agtggattgg atctgtgcca gtaatgacaa     4620

aattattttt ttgacttgct tgcctgaata aattgaagaa ttgctttcag tttgggtttt     4680

gtatattctt aagtagccat tgaaatttat attcttaact aggtcaaaaa ataatgagcc     4740

ataagtttat gtcctctcac ttagacattt tctctttaaa aaggtatttt cttctttata     4800

aacattttaa aagagccttc ccttcttaaa ctaactccag tgcatgaagt gtgaaaatat     4860

tttaaaatga catttttact aatatgagca agtcatgtaa acattgaaga acttggtaac     4920

atattagtaa atggatatta ccaaatgttt tcatcgttaa ttactttgcg ttccaccaaa     4980

atatctttac taaaatgtgc ttggtgtagt ttgtttattg tctaaattag taccagtcat     5040

cttatttctg caaaatgagt atcaatgtga aaaagacacg tgaagattaa gcatgtttga     5100

aaataaaatg gtcaattaca tttcaattta cataggccaa caactgttcc atactttgtt     5160

tgtaaacatt taatttctct actggacaaa attaatattt ggctttacat tgaattttga     5220

gctgtgaaga ataaattatg tatcatttta gcatattaaa cagtagtaag tctagcacat     5280

agtctcagcc acttaaaaca aaagtttttt tgtttgtttg tttgtttgtt tttttgagat     5340

ggagtctcac tctgttgccc aggctggagt gcagtggcgt gatctcggct tactgcaacc     5400

tccgcctccc gggttcaagc gattctcctg cctcagcctc ccaagtaact gggacaacag     5460

gcgcgtccca ccacacccag ctaatttttt atacttttag tagagatggg gtttcagcat     5520

attggccagg ctggtctcga actcctgacc ttgtgatcca cccgcctcgg cctcccaaag     5580

tgctgggatt ataggcgtga gcccctgcac ccggccaaaa gttgattttt aattacataa     5640

aaatcgtaaa aacttctagt aaaaacttga tttggtgaat acagttatat ttaaaaacct     5700

taaggtgaca agcattttct atgcctaaat cttcattggt ttgcctggaa agagtctctg     5760

ttaaaagatt ttccatattc aaagtaaaag gaaagatttc ttgctttcta attgtctttt     5820

ggacacatgc ctattttctt tgaggtataa acctttagat gtgaaaaatg taatttcatt     5880

ctgctattgt gtgtgcttgt gtgtgtgtaa ttgaaaaaac tgggaaatcc tgctttgttg     5940

gtaataaatc aatattttta tattc                                           5965


<210>  1693
<211>  3716
<212>  DNA
<213>  homo sapiens

<400>  1693
attcccatgg cccgggctca ggcgtccaac ctgctgccgc ctgggccccg ccgagcggag       60

ctagcgccgc gcgcagagca cacgctcgcg ctccagctcc cctcctgcgc ggttcatgac      120

tgtgtcccct gaccgcagcc tctgcgagcc cccgccgcag gaccacggcc cgctccccgc      180

cgccgcgagg gccccgagcg aaggaaggaa gggaggcgcg ctgtgcgccc cgcggagccc      240

gcgaaccccg ctcgctgccg gctgcccagc ctggctggca ccatgctgcc cgcgcgctgc      300

gcccgcctgc tcacgcccca cttgctgctg gtgttggtgc agctgtcccc tgctcgcggc      360

caccgcacca caggccccag gtttctaata agtgaccgtg acccacagtg caacctccac      420

tgctccagga ctcaacccaa acccatctgt gcctctgatg gcaggtccta cgagtccatg      480

tgtgagtacc agcgagccaa gtgccgagac ccgaccctgg gcgtggtgca tcgaggtaga      540

tgcaaagatg ctggccagag caagtgtcgc ctggagcggg ctcaagccct ggagcaagcc      600

aagaagcctc aggaagctgt gtttgtccca gagtgtggcg aggatggctc ctttacccag      660

gtgcagtgcc atacttacac tgggtactgc tggtgtgtca ccccggatgg gaagcccatc      720

agtggctctt ctgtgcagaa taaaactcct gtatgttcag gttcagtcac cgacaagccc      780

ttgagccagg gtaactcagg aaggaaagat gacgggtcta agccgacacc cacgatggag      840

acccagccgg tgttcgatgg agatgaaatc acagccccaa ctctatggat taaacacttg      900

gtgatcaagg actccaaact gaacaacacc aacataagaa attcagagaa agtctattcg      960

tgtgaccagg agaggcagag tgccctggaa gaggcccagc agaatccccg tgagggtatt     1020

gtcatccctg aatgtgcccc tgggggactc tataagccag tgcaatgcca ccagtccact     1080

ggctactgct ggtgtgtgct ggtggacaca gggcgcccgc tgcctgggac ctccacacgc     1140

tacgtgatgc ccagttgtga gagcgacgcc agggccaaga ctacagaggc ggatgacccc     1200

ttcaaggaca gggagctacc aggctgtcca gaagggaaga aaatggagtt tatcaccagc     1260

ctactggatg ctctcaccac tgacatggtt caggccatta actcagcagc gcccactgga     1320

ggtgggaggt tctcagagcc agaccccagc cacaccctgg aggagcgggt agtgcactgg     1380

tatttcagcc agctggacag caatagcagc aacgacatta acaagcggga gatgaagccc     1440

ttcaagcgct acgtgaagaa gaaagccaag cccaagaaat gtgcccggcg tttcaccgac     1500

tactgtgacc tgaacaaaga caaggtcatt tcactgcctg agctgaaggg ctgcctgggt     1560

gttagcaaag aagtaggacg cctcgtctaa ggagcagaaa acccaagggc aggtggagag     1620

tccagggagg caggatggat caccagacac ctaaccttca gcgttgccca tggccctgcc     1680

acatcccgtg taacataagt ggtgcccacc atgtttgcac ttttaataac tcttacttgc     1740

gtgttttgtt tttggtttca ttttaaaaca ccaatatcta ataccacagt gggaaaagga     1800

aagggaagaa agactttatt ctctctctta ttgtaagttt ttggatctgc tactgacaac     1860

ttttagaggg ttttgggggg gtgggggagg gtgttgttgg ggctgagaag aaagagattt     1920

atatgctgta tataaatata tatgtaaatt gtatagttct tttgtacagg cattggcatt     1980

gctgtttgtt tatttctctc cctctgcctg ctgtgggtgg tgggcactct ggacacatag     2040

tccagctttc taaaatccag gactctatcc tgggcctact aaacttctgt ttggagactg     2100

acccttgtgt ataaagacgg gagtcctgca attgtactgc ggactccacg agttcttttc     2160

tggtgggagg actatattgc cccatgccat tagttgtcaa aattgataag tcacttggct     2220

ctcggccttg tccagggagg ttgggctaag gagagatgga aactgccctg ggagaggaag     2280

ggagtccaga tcccatgaat agcccacaca ggtaccggct ctcagagggt ccgtgcattc     2340

ctgctctccg gacccccaaa gggcccagca ttggtgggtg caccagtatc ttagtgaccc     2400

tcggagcaaa ttatccacaa aggatttgca ttacgtcact cgaaacgttt tcatccatgc     2460

ttagcatcta ctctgtataa cgcatgagag gggaggcaaa gaagaaaaag acacacagaa     2520

gggcctttaa aaaagtagat atttaatatc taagcagggg aggggacagg acagaaagcc     2580

tgcactgagg ggtgcggtgc caacagggaa actcttcacc tccctgcaaa cctaccagtg     2640

aggctcccag agacgcagct gtctcagtgc caggggcaga ttgggtgtga cctctccact     2700

cctccatctc ctgctgttgt cctagtggct atcacaggcc tgggtgggtg ggttggggga     2760

ggtgtcagtc accttgttgg taacactaaa gttgttttgt tggtttttta aaaacccaat     2820

actgaggttc ttcctgttcc ctcaagtttt cttatgggct tccaggcttt aagctaattc     2880

cagaagtaaa actgatcttg ggtttcctat tctgcctccc ctagaagggc aggggtgata     2940

acccagctac agggaaatcc cggcccagct ttccacaggc atcacaggca tcttccgcgg     3000

attctagggt gggctgccca gccttctggt ctgaggcgca gctccctctg cccaggtgct     3060

gtgcctattc aagtggcctt caggcagagc agcaagtggc ccttagcgcc ccttcccata     3120

agcagctgtg gtggcagtga gggaggttgg gtagccctgg actggtcccc tcctcagatc     3180

acccttgcaa atctggcctc atcttgtatt ccaacccgac atccctaaaa gtacctccac     3240

ccgttccggg tctggaaggc gttggcacca caagcactgt ccctgtggga ggagcacaac     3300

cttctcggga caggatctga tggggtcttg ggctaaagga ggtccctgct gtcctggaga     3360

aagtcctaga ggttatctca ggaatgactg gtggccctgc cccaacgtgg aaaggtggga     3420

aggaagcctt ctcccattag ccccaatgag agaactcaac gtgccggagc tgagtgggcc     3480

ttgcacgaga cactggcccc actttcaggc ctggaggaag catgcacaca tggagacggc     3540

gcctgcctgt agatgtttgg atcttcgaga tctccccagg catcttgtct cccacaggat     3600

cgtgtgtgta ggtggtgttg tgtggttttc ctttgtgaag gagagaggga aactatttgt     3660

agcttgtttt ataaaaaata aaaaatgggt aaatcttgaa aaaaaaaaaa aaaaaa         3716


<210>  1694
<211>  4244
<212>  DNA
<213>  homo sapiens

<400>  1694
gcgcgcgggc ggcgtagccg gcctgtctgg gccgcctcgt ggggagggag ggggcgcccg       60

gccgcccggc ggcgaccccg gggcctggcc gccaccatgg gcttcgagct ggaccgcttc      120

gacggcgacg tggacccgga cctgaagtgc gcgctgtgcc acaaggtcct ggaggacccg      180

ctgaccacgc cgtgcggcca cgtcttctgc gccggctgcg tgctgccctg ggtggtgcag      240

gagggcagct gcccggcgcg ctgccgcggt cgcctgtcgg ccaaagagct caaccacgtc      300

ctgccgctca agcgccttat cctcaagctg gacatcaagt gcgcgtacgc gacgcgcggc      360

tgcggccggg tggtcaagct gcagcagctg ccggagcacc tcgagcgctg cgacttcgcg      420

cccgcgcgct gtcgccacgc gggttgcggc caggtgctgc tgcggcgcga cgtggaggcg      480

cacatgcgcg acgcctgcga cgcgcggcca gtgggccgct gccaggaggg ctgcgggcta      540

cccttgacgc acggcgagca gcgcgcgggc ggccactgct gcgcgcgagc gctgcgggcg      600

cacaacggcg cgctccaggc ccgcctgggc gcgctgcaca aggcgctcaa gaaggaggcg      660

ctgcgcgctg ggaagcgcga gaagtcgctg gtggcccagc tggccgcggc gcagcttgag      720

ctgcagatga ccgcgctgcg ctaccagaag aaattcaccg aatacagcgc gcgcctcgac      780

tcgctcagcc gctgcgtggc cgcgccgccc ggcggcaagg gcgaagaaac caaaagtctg      840

actcttgtcc tgcatcggga ctccggctcc ctgggattca atattattgg tggccggccg      900

agtgtggata accacgatgg atcatccagt gaaggaatct ttgtatccaa gatagttgac      960

agtgggcctg cagccaagga aggaggcctg caaattcatg acaggattat tgaggtcaac     1020

ggcagagact tatccagagc aactcatgac caggctgtgg aagctttcaa gacagccaag     1080

gagcccatag tggtgcaggt gttgagaaga acaccaagga ccaaaatgtt cacgcctcca     1140

tcagagtctc agctggtgga cacgggaacc caaaccgaca tcacctttga acatatcatg     1200

gccctcacta agatgtcctc tcccagccca cccgtgctgg atccctatct cttgccagag     1260

gagcatccct cagcccatga atactacgat ccaaatgact acattggaga catccatcag     1320

gagatggaca gggaggagct ggagctggag gaagtggacc tctacagaat gaacagccag     1380

gacaagctgg gcctcactgt gtgctaccgg acggacgatg aagacgacat tgggatttat     1440

atcagtgaga ttgaccctaa cagcattgca gccaaggatg ggcgcatccg agaaggagac     1500

cgcattatcc agattaatgg gatagaggtg cagaaccgtg aagaggctgt ggctcttcta     1560

accagtgaag aaaataaaaa cttttcattg ctgattgcaa ggcctgaact ccagctggat     1620

gagggctgga tggatgatga caggaacgac tttctggatg acctgcacat ggacatgctg     1680

gaggagcagc accaccaggc catgcaattc acagctagcg tgctgcagca gaagaagcac     1740

gacgaagacg gtgggaccac agatacagcc accatcttgt ccaaccagca cgagaaggac     1800

agcggtgtgg ggcggaccga cgagagcacc cgtaatgacg agagctcgga gcaagagaac     1860

aatggcgacg acgccaccgc atcctccaac ccgctggcgg ggcagaggaa gctcacctgc     1920

agccaggaca ccttgggcag cggcgacctg cccttcagca acgagtcttt catttcggcc     1980

gactgcacgg acgccgacta cctggggatc ccggtggacg agtgcgagcg cttccgcgag     2040

ctcctggagc tcaagtgcca ggtgaagagc gccacccctt acggcctgta ctaccctagc     2100

ggccccctgg acgccggcaa gagtgaccct gagagcgtgg acaaggagct ggagctgctg     2160

aacgaagagc tgcgcagcat cgagctggag tgcctgagca tcgtgcgcgc ccacaagatg     2220

cagcagctca aggagcagta ccgcgagtcc tggatgctgc acaacagcgg cttccgcaac     2280

tacaacacca gcatcgacgt gcgcagacac gagctctcag atatcaccga gctcccggag     2340

aaatccgaca aggacagctc gagcgcctac aacacaggcg agagctgccg cagcaccccg     2400

ctcaccctgg agatctcccc cgacaactcc ttgaggagag cggcggaggg catcagctgc     2460

ccgagcagcg aaggggctgt ggggaccacg gaagcctacg ggccagcctc caagaatctg     2520

ctctccatca cggaagatcc cgaagtgggc acccctacct atagcccgtc cctgaaggag     2580

ctggacccca accagcccct ggaaagcaaa gagcggagag ccagcgacgg gagccggagc     2640

cccacgccca gccagaagct gggcagcgcc tacctgccct cctatcacca ctccccatac     2700

aagcacgcgc acatcccggc gcacgcccag cactaccaga gctacatgca gctgatccag     2760

cagaagtcgg ccgtggagta cgcgcaaagc cagatgagcc tggtgagcat gtgcaaggac     2820

ctgagctctc ccaccccgtc ggagccgcgc atggagtgga aggtgaagat ccgcagcgac     2880

gggacgcgct acatcaccaa gaggcccgtg cgggaccgcc tgctgcggga gcgcgccctg     2940

aagatccggg aagagcgcag cggcatgacc accgacgacg acgcggtgag cgagatgaag     3000

atggggcgct actggagcaa ggaggagagg aagcagcacc tggtgaaggc caaggagcag     3060

cggcggcggc gcgagttcat gatgcagagc aggttggatt gtctcaagga gcagcaagca     3120

gccgatgaca ggaaggagat gaacattctc gaactgagcc acaaaaagat gatgaagaag     3180

aggaataaga aaatcttcga taactggatg acgatccaag aactcttaac ccacggcaca     3240

aaatccccgg acggcactag agtatacaat tccttcctat cggtgactac tgtataattt     3300

tcacttctgc attatgtaca taaaggagac cactaccact ggggtagaaa ttcctgcctc     3360

gttcaatgcg gcaagttttt gtatataaga taagtacggt cttcatgttt atagtccaaa     3420

tttgcaaacc ctacaactct gggtgtcata ggtctatttt aagggaagag agagaaaaac     3480

acccttacta tcttggaagg caatattaac aaacagagct tttttcaaat agcaattgta     3540

cttttctacc tgtacccttt tacataaagt gtttaaattt cagaaagatc ttttattaag     3600

catactttca cagaataact tgtttaaact atattcatat aaaaaagtta aacacgcttt     3660

ttttcctgcc taaaacacaa atacaactgc cagtatgtat ttttaatgga accctatttt     3720

ataatggtac gttactgaat gtgtttcata tgcgtgaccg ttaagatatt atcatttagg     3780

tgaaggtttc aactcaaaac cacccaaccc ggtggttaac gatttaatac atataaccaa     3840

accggcagcg tttagagttg ggatatacat ttaaacattt tcctggttaa ggttcccaag     3900

agagtgtaaa ggttttagca gaaagcaaaa tatcttgcat ctttatggaa gtttaaagca     3960

tgtttgcaaa tattgcagcc cattgaaaga atttgcatgt acaggaaagt tgtggatgga     4020

gacggtttgt ggaattttaa gtgctcattg tagtaaactt ttgctttgta gatttgaagg     4080

tacagactta tacaggcaag ttcacaaaat catgattagt tacaaacagt aaaatgaagt     4140

taaaataaat tattattttc tatttgatat gttttgatgt gattcctcat tttgcagtgg     4200

tgcctataaa ataaaagcct tttgcagtgt ttaaaaaaaa aaaa                      4244


<210>  1695
<211>  1688
<212>  DNA
<213>  homo sapiens

<400>  1695
gcgcccttca ttttcatttc ttgaaacaac agccttgcag gccgagccgc tgttcccgag       60

aactcggcag ccacagggag caggttgcat ggacccagga gcgcgagagg ccctgctctg      120

ccagcttcgg ccaatcagag gccagggagc ggtgggcgtg acgtggggcg gtgcgcgggg      180

ctgggcggcg gctgaggcgc gtgctctcgc gtggtcgctg ggtctgcgtc ttcccgagcc      240

agtgtgctga gctctccgcg tcgcctctgt cgcccgcgcc tggcctaccg cggcactccc      300

ggctgcacgc tctgcttggc ctcgccatgc cggtggacct cagcaagtgg tccgggccct      360

tgagcctgca agaagtggac gagcagccgc agcacccgct gcatgtcacc tacgccgggg      420

cggcggtgga cgagctgggc aaagtgctga cgcccaccca ggttaagaat agacccacca      480

gcatttcgtg ggatggtctt gattcaggga agctctacac cttggtcctg acagacccgg      540

atgctcccag caggaaggat cccaaataca gagaatggca tcatttcctg gtggtcaaca      600

tgaagggcaa tgacatcagc agtggcacag tcctctccga ttatgtgggc tcggggcctc      660

ccaagggcac aggcctccac cgctatgtct ggctggttta cgagcaggac aggccgctaa      720

agtgtgacga gcccatcctc agcaaccgat ctggagacca ccgtggcaaa ttcaaggtgg      780

cgtccttccg taaaaagtat gagctcaggg ccccggtggc tggcacgtgt taccaggccg      840

agtgggatga ctatgtgccc aaactgtacg agcagctgtc tgggaagtag ggggttagct      900

tggggacctg aactgtcctg gaggccccaa gccatgttcc ccagttcagt gttgcatgta      960

taatagattt ctcctcttcc tgcccccctt ggcatgggtg agacctgacc agtcagatgg     1020

tagttgaggg tgacttttcc tgctgcctgg cctttataat tttactcact cactctgatt     1080

tatgttttga tcaaatttga acttcatttt ggggggtatt ttggtactgt gatggggtca     1140

tcaaattatt aatctgaaaa tagcaaccca gaatgtaaaa aagaaaaaac tggggggaaa     1200

aagaccaggt ctacagtgat agagcaaagc atcaaagaat ctttaaggga ggtttaaaaa     1260

aaaaaaaaaa aaaaaagatt ggttgcctct gcctttgtga tcctgagtcc agaatggtac     1320

acaatgtgat tttatggtga tgtcactcac ctagacaacc agaggctggc attgaggcta     1380

acctccaaca cagtgcatct cagatgcctc agtaggcatc agtatgtcac tctggtccct     1440

ttaaagagca atcctggaag aagcaggagg gagggtggct ttgctgttgt tgggacatgg     1500

caatctagac cggtagcagc gctcgctgac agcttgggag gaaacctgag atctgtgttt     1560

tttaaattga tcgttcttca tgggggtaag aaaagctggt ctggagttgc tgaatgttgc     1620

attaattgtg ctgtttgctt gtagttgaat aaaaatagaa acctgaatga aggaaaaaaa     1680

aaaaaaaa                                                              1688


<210>  1696
<211>  4319
<212>  DNA
<213>  homo sapiens

<400>  1696
gttgtttgct aatttctgga ctaattatgc aatttcattt ttttttcttg attcagccaa       60

atgtgtgtgt gtgtgtttaa actgtgcttt ctaagcacag tcaggtagca aaagtaataa      120

aaaggatggt tgaacaagtt ttcttgtatg ttccaggata tgtttgggac ttttctttgt      180

ttattatatg agttgttccc tttgaaatta aagctatttt gtaggttttg tgggacataa      240

tttgataagt agagttaatt aaatttcttc tggaagagat ctaaattctt attcttagtg      300

agagactgta gttaaaggaa ggcttttaga acttgggttc aaggaagatg gagatgcgtc      360

ggaagctctt tggcgggggt gaggaagttc agaaagtgtg cattttcctt ctggcattta      420

ggtcttgtcc gtgtgatttg gtggtgcttg ggtcataagc ctgattaaaa ttcagggaca      480

tgtaccacgg cggccaaagc ggaattaatt tttttatatg gggactggag cgctgaaaag      540

ttgttcctga ccaggctcta atgagaaatt cctctctccc caggttatga agacagtatg      600

gagtttccag accatagtag acatttgcta cagtgtctga gcgagcagag acaccagggt      660

tttctttgtg actgcactgt tctggtggga gatgcccagt tccgagcgca ccgagctgta      720

ctggcttcat gcagcatgta tttccacctc ttttacaagg accagctgga caaaagagac      780

attgttcatc tgaacagcga cattgttaca gcccccgctt tcgctctcct gcttgaattc      840

atgtatgaag ggaaactcca gttcaaagac ttgcccattg aagacgtgct agcagctgcc      900

agttatctcc acatgtatga cattgtcaaa gtctgcaaaa agaagctgaa agagaaagcc      960

accacggagg cagacagcac caaaaaggaa gaagatgctt caagttgttc ggacaaagtc     1020

gagagtctct ccgatggcag cagccacata gcaggcgatt tgcccagtga tgaagatgaa     1080

ggagaagatg aaaaattgaa catcctgccc agcaaaaggg acttggcggc cgagcctggg     1140

aacatgtgga tgcgattgcc ctcagactca gcaggcatcc cccaggctgg cggagaggca     1200

gagccacacg ccacagcagc tggaaaaaca gtagccagcc cctgcagctc aacagagtct     1260

ttgtcccaga ggtctgtcac ctccgtgagg gattcggcag atgttgactg tgtgctggac     1320

ctgtctgtca agtccagcct ttcaggagtt gaaaatctga acagctctta tttctcttca     1380

caggacgtgc tgagaagcaa cctggtgcag gtgaaggtgg agaaagaggc ttcctgtgat     1440

gagagtgatg ttggcactaa tgactatgac atggaacata gcactgtgaa agaaagtgtg     1500

agcactaata acagggtaca gtatgagccg gcccatctgg ctcccctgag ggaggactcg     1560

gtcttgaggg agctggaccg ggaggacaaa gccagtgatg atgagatgat gaccccagag     1620

agcgagcgtg tccaggtgga gggaggcatg gagagcagtc tgctccccta cgtctccaac     1680

atcctgagcc ccgcgggcca gatcttcatg tgccccctgt gcaacaaggt cttccccagc     1740

ccccacatcc tgcagatcca cctgagcacg cacttccgcg agcaggacgg catccgcagc     1800

aagcccgccg ccgatgtcaa cgtgcccacg tgctcgctgt gtgggaagac tttctcttgc     1860

atgtacaccc tcaagcgcca cgagaggact cactcggggg agaagcccta cacatgcacc     1920

cagtgcggca agagcttcca gtactcgcac aacctgagcc gccatgccgt ggtgcacacc     1980

cgcgagaagc cgcacgcctg caagtggtgc gagcgcaggt tcacgcagtc cggggacctg     2040

tacagacaca ttcgcaagtt ccactgtgag ttggtgaact ccttgtcggt caaaagcgaa     2100

gcactgagct tgcctactgt cagagactgg accttagaag atagctctca agaactttgg     2160

aaataatttt atatatatat aaataatata tatatatata catatatata aatagatctc     2220

tatatagttg tggtacggtc taaaagcagt cttgtttcct ggaaataaaa agttgggata     2280

ttaacttgtt tttgcacttt agaatagcat gagaatctca ctaatttagc attctgataa     2340

aagaaacttt agagcaagtc agaatagaga ggtgtttttc ctttgagggg ataggggaag     2400

taagccaata agaacctttt aaacaaatcg tcctgtcaca aaatgctttc atatggctta     2460

attttgtcaa cactgcattg tcttttgagc tcttttttcc cccccaacaa agtttttttg     2520

ttttttgttt ttttttttaa gtagaaattc cctccagttt tattagcctc tttatatgtc     2580

tcaaattgca tgaatttttt ctggctgttg gaaacctgaa tgcttttaga cccaaatgga     2640

aaatttctga aatgctggat tatctatttt taaacaagca gttgacttaa aactttctgt     2700

ggcaacttct ggttttctga cagttcccag tgagagaaat gctgaaagta cactgggatc     2760

actgggacac tgtcttatga aggtttgctt gggatgaaaa aggatattgc agcttcagca     2820

gtgttgaact gtgtgtttaa aaatgtgaat tactgttatt gtatactgta attgattaca     2880

tgggctgggg gggtgtcaaa gaacttgaca ggttgtgttg atgctcttag ttgagtcttg     2940

aaaagtaaat attaacgcta cagaaatgca tgagtttcaa tatatttttt gtctttgttt     3000

gcattgtata actttaacga gtgagtttaa aattatttaa tttccttaga aaaatagcac     3060

catttggaaa aaaaaactgg tgttatgaag aacgtaaatg cactgttttt atttttattt     3120

tatataattt aaattgactt tcccactgtc tttaagttga aactgttaag ctgaataaaa     3180

acttaagctg caaattgata acttcgctac ataacaagga aaatataaat gtttacaaac     3240

agcttaaaga tttgcatgtg cagtgtgcat ttataacaaa cttctaattg cacaaaaccc     3300

atgccagctc agagtttagg tgtacacatt tacccagttg agcgttctta gaataactac     3360

tgcacaagtt gacaataggt cgttctctct ttttttttgt ttgctccctt tttctttttc     3420

tccccttcct ccttaccctc cctcccttac tctccccccc caccaccacc ctccaccccc     3480

aactcatgaa aagattctat ggactgaaaa agccccaggc tgaaaggact ggactgcctt     3540

gattgacatg gggaaggggg ttagtagact atgtggattg cggcagcaga ggctgcagcc     3600

taacgtgtgg ttttaatgac cagcacgcaa ggcaaaagca ttttgcacag tgtttgtttt     3660

cctgtcttgc acttacaaat aaggtctatg ggagtagcat ggaaaacgtt tgctgttttt     3720

cccttttttt tttaattgct tttgtttaaa atttgatcgc cttaactact gtaaacatag     3780

cctatttttg tgcttaagat actgaatgga aaactccatt gtgtgttgct ggactgtttt     3840

ggaaatattt ggttaaatgt gtgttaattt ggctgtaatg gcatttaaag caaacaaaca     3900

aacaaaaaaa gctgtgaaaa tggccttgga gcattatctt tagttacttg aagagtttct     3960

agttttttta aaatacagtt tatgttaaaa taatttttat taatttagag aagacaatca     4020

atgtctgtga gaaaacggac tttcttttgg attttctttt tgtggtcatt gtgagtgatt     4080

gctttttcct tttcttagtt tcacattctt cctttgttct aaaacttaga ctgacatcta     4140

gctttgacaa tcatagtatg ttttattttc ctgaggggga ataacttata atgctgttta     4200

gttttgtact attggtgtgt tggtgaattt ttaaactgtg tgctaactgc aataaattat     4260

atgaactgag aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa      4319


<210>  1697
<211>  3305
<212>  DNA
<213>  homo sapiens

<400>  1697
gcctaacttg cgcgctgaga tttccggcgt gggagcagag gtctgagtct tgcgtgggtc       60

ctctatatag ggtgagaagc gtggcgctcg gttcctgcct cggggaagtc ctggcgcaga      120

tgggccacgg ggccggcgtg gcggcgcctg ggaccgactg aggcctaggc gccggagccg      180

gccgcgcctg ggctggagcg gggctcctcg gcctggactg ggagcccccg gccccgggct      240

cctgctggcg ccgtccaacc ttacatgggt tcagggcgcc ttcgtaggcg ggcacggctg      300

gtttcgggct aaggcgctct ggagacctga cgatggcgtc gggcccgggc tcccaggaac      360

gggaagggct cctgatagtg aagctggagg aggactgcgc ctggagccag gagctgcccc      420

cacctgaccc aggaccgagc cccgaggcct cccacttgcg cttcagacgg ttccgcttcc      480

aagaggcagc tggtccccgg gaagccctca gccggctcca agagctttgc catgggtggc      540

ttcggcctga gatgcgcacg aaggagcaga tcttggagct gctggtgtta gagcagttcc      600

tgaccatcct gccccaggag atccagagca gggtgcagga gctgcatccg gagagcggcg      660

aagaagcggt gacccttgtg gaggatatgc agagagagct tgggagactg agacaacagg      720

tcacaaacca tgggcgggga acagaagtgc ttttggagga gcctttgcct ctggaaacag      780

cacgagagtc accgagcttc aagctggagc caatggagac tgagcgaagc cctggcccca      840

ggctgcagga gctgctaggc cccagccccc aaagggaccc ccaggctgta aaggagaggg      900

cattatctgc tccctggctt tctctttttc ctcctgaagg gaacatggaa gacaaggaga      960

tgactgggcc ccagttgcct gagagcttag aggacgtggc aatgtacatc tcccaggagg     1020

agtgggggca tcaggatcct agtaagaggg ccctctccag ggacacggtg caggagagtt     1080

atgagaatgt ggactcactg gagtctcaca ttcccagtca ggaggtccca ggcacccagg     1140

tgggacaagg aggaaagcta tgggatccca gtgtccagag ctgcaaggag ggcctgagcc     1200

ccagaggccc agctccagga gaagagaaat ttgagaacct ggaaggtgtt ccgtctgtat     1260

gctctgagaa catccaccct caggtgctgc ttcctgacca ggcccgaggg gaggtgccct     1320

ggagtcctga gctgggaaga cctcatgacc ggtcgcaagg ggattgggcg cctcccccag     1380

agggtggaat ggagcaggcc ttggcaggag cctcaagtgg cagagaactg gggcgaccga     1440

aggaactgca gccaaagaaa ctccatttat gtcccttgtg tggcaaaaat ttctctaaca     1500

actcaaacct aattaggcac cagagaatac atgcagctga aagactgtgt atgggtgtgg     1560

actgcactga aatctttggt gggaacccac gtttcctgtc actacacaga gcacacctgg     1620

gagaggaggc ccacaagtgc cttgaatgtg ggaaatgctt cagtcagaac acccatctga     1680

ctcgccacca acgcacccac acgggtgaga agccctatca gtgcaacatt tgcggaaaat     1740

gtttctcctg caactccaac ctccacaggc accagagaac gcacactggg gagaagccct     1800

acaagtgccc tgagtgtggg gagatctttg ctcacagttc caacctcctt cggcaccaga     1860

gaattcacac tggagagcga ccttataagt gtcccgagtg tgggaaaagt ttctctcgga     1920

gttcacacct cgtcattcac gaaagaactc atgagagaga gagactttac cccttctctg     1980

agtgtgggga agctgtgagt gacagcaccc cctttcttac aaaccatgga gcccataagg     2040

cagagaagaa gctctttgaa tgtttgactt gtgggaaaag cttccggcag ggcatgcacc     2100

tcaccagaca tcagagaaca cacacaggag agaaaccgta taaatgtacc ctttgtgggg     2160

aaaacttctc tcatagatcc aatttaatca ggcaccagag aatccacaca ggagaaaaac     2220

cctatacctg tcatgagtgc ggagacagct tctctcacag ctccaatcgg attcgccacc     2280

tgagaacgca tacgggagag agaccctata aatgttctga atgtggagaa agcttctctc     2340

ggagttcccg tcttatgagt catcagagaa ctcacacagg ttagtaacag tggggtttct     2400

ctttgcccca ggtgaggtgg catattcaga ggagcctgtt ggcaagagct ggtattccct     2460

gcccagccga ccaaatgacc tctgcattct tcaggtaatg ggggctcatt gtgagggagg     2520

tgcagaggca gcagaggatt ggcataaaac tgaaaaggag ttctgtctgc atgagaaagg     2580

atggcaagtc tctgaggtga cctcagggtg gaattctctg ttaagtccac cctgccccag     2640

ggtgctccta ccctcttggt ctttttaaag ccaaggtgcg atttgggcac ctgactgtcc     2700

agtttacctt aacaagtttg ggaatccatg tgatgttttt gatacttctt cctcatttgg     2760

gacattcagt aggagcattt gggcttccgg ggcccctgag accaaagaag aggggccaag     2820

taccctggga aatcagctga aggtcaacaa aagactggtt gtgagttgca gctgtcccga     2880

aggccccagt tgggaagcca tgggcagtcc agatcaagcc accacgtgcc ctacgatggc     2940

ctaacaggag tgcccattgg cagattacac atgtaaatat gacctcagac aaaaaggaac     3000

cagaggccca agggcaataa taaggtggaa tttgcaggtc agcccaggaa ttggcagagg     3060

aagtaggtgt ctgataaccc tttgtggaga atgagattcc ccccacctgt gtgagaaaaa     3120

taaacagctc tggagtcttg ttcctgactc cagaggaacg agagcattcc aggaaagaga     3180

gattccctgg aaaattgaaa atgtgaatcc tagggggaaa ttggggattg tgtctttccc     3240

tgttgaaaat gtttggatgg gaataaatat cttcaggaaa cataaaaaaa aaaaaaaaaa     3300

aaaaa                                                                 3305


<210>  1698
<211>  2683
<212>  DNA
<213>  homo sapiens

<400>  1698
agggcggtgt caatgcaccc tccagcggtg cgcgcaggcg ggagaaggga gggcggcccg       60

ggcaagtgag acagttaagg cagtgtcccc accacacccc cacccagatt ggccacgccg      120

agctggttct tgacagaagg ccttcgcgga ggaagagggg gcacagctgc acaggacacc      180

ctacggagcc tgcgggcgtg gaactttgcc aggcgcacgg gaacgcgcgc ccttcctgtc      240

agcctcccgg ggcgccaggc tcccgcggcc cgcagcggga cagcctcagt tgtgtgggct      300

ggacccagtc gctggggtac cgaccagtcc tggaaggcgc agaggacgtg gagtggggag      360

gctgccttcc tatgtgcgaa gggccagccg ggcacgcagt cctcagaccc tagtccgcac      420

ccggcaggtc cccacggcac ctgctgcgcc ctcctcgccg ctcccccaac ctccccatct      480

cagaaaacta ccagttctct cccgcccccc ggcgcccctt tcccaggaac gtgcggaggc      540

gggagaagag gaagacagga agggggtggg gatgtgaagc gaccgtccca gccttccccg      600

cccgccaccc ccaccccaac tcggcagccg tcacgtgatg cctggagtgg gaggtgggga      660

gaaaaggcga gacttttgtg ggtgctcccg atcgccagta gttccttcag tctcagccgc      720

caactccgga ggcgcggtgc tcggcccggg agcgcgagcg ggaggagcag agacccgcag      780

ccgggagccc gagcgcgggc gatgcaggct ccgcgagcgg cacctgcggc tcctctaagc      840

tacgaccgtc gtctccgcgg cagcagcgcg ggccccagca gcctcggcag ccacagccgc      900

tgcagccggg gcagcctccg ctgctgtcgc ctcctctgat gcgcttgccc tctcccggcc      960

ccgggactcc gggagaatgt gggtcctagg catcgcggca actttttgcg gattgttctt     1020

gcttccaggc tttgcgctgc aaatccagtg ctaccagtgt gaagaattcc agctgaacaa     1080

cgactgctcc tcccccgagt tcattgtgaa ttgcacggtg aacgttcaag acatgtgtca     1140

gaaagaagtg atggagcaaa gtgccgggat catgtaccgc aagtcctgtg catcatcagc     1200

ggcctgtctc atcgcctctg ccgggtacca gtccttctgc tccccaggga aactgaactc     1260

agtttgcatc agctgctgca acacccctct ttgtaacggg ccaaggccca agaaaagggg     1320

aagttctgcc tcggccctca ggccagggct ccgcaccacc atcctgttcc tcaaattagc     1380

cctcttctcg gcacactgct gaagctgaag gagatgccac cccctcctgc attgttcttc     1440

cagccctcgc ccccaacccc ccacctccct gagtgagttt cttctgggtg tccttttatt     1500

ctgggtaggg agcgggagtc cgtgttctct tttgttcctg tgcaaataat gaaagagctc     1560

ggtaaagcat tctgaataaa ttcagcctga ctgaattttc agtatgtact tgaaggaagg     1620

aggtggagtg aaagttcacc cccatgtctg tgtaaccgga gtcaaggcca ggctggcaga     1680

gtcagtcctt agaagtcact gaggtgggca tctgcctttt gtaaagcctc cagtgtccat     1740

tccatccctg atgggggcat agtttgagac tgcagagtga gagtgacgtt ttcttagggc     1800

tggagggcca gttcccactc aaggctccct cgcttgacat tcaaacttca tgctcctgaa     1860

aaccattctc tgcagcagaa ttggctggtt tcgcgcctga gttgggctct agtgactcga     1920

gactcaatga ctgggactta gactggggct cggcctcgct ctgaaaagtg cttaagaaaa     1980

tcttctcagt tctccttgca gaggactggc gccgggacgc gaagagcaac gggcgctgca     2040

caaagcgggc gctgtcggtg gtggagtgcg catgtacgcg caggcgcttc tcgtggttgg     2100

cgtgctgcag cgacaggcgg cagcacagca cctgcacgaa cacccgccga aactgctgcg     2160

aggacaccgt gtacaggagc gggttgatga ccgagctgag gtagaaaaac gtctccgaga     2220

aggggaggag gatcatgtac gcccggaagt aggacctcgt ccagtcgtgc ttgggtttgg     2280

ccgcagccat gatcctccga atctggttgg gcatccagca tacggccaat gtcacaacaa     2340

tcagccctgg gcagacacga gcaggaggga gagacagaga aaagaaaaac acagcatgag     2400

aacacagtaa atgaataaaa ccataaaata tttagcccct ctgttctgtg cttactggcc     2460

aggaaatggt accaattttt cagtgttgga cttgacagct tcttttgcca caagcaagag     2520

agaatttaac actgtttcaa acccggggga gttggctgtg ttaaagaaag accattaaat     2580

gctttagaca gtgtatttat accagttgat gtctgttaat tttaaaaaaa tgttttcatt     2640

ggtgtttgtt tgcgtatcca gaaagcagtt catgttatcc ata                       2683


<210>  1699
<211>  1453
<212>  DNA
<213>  homo sapiens

<400>  1699
cgcaaaggac ctgacgacgt gctgcgtcgt tacttttgaa acgcttggcg gggaagtgct       60

gttggagccg ctgtggttgc tgtccgcgga gtggaagcgc gtgcttttgt ttgtgtccct      120

ggccatggcg ctgcagctct cccgggagca gggaatcacc ctgcgcggga gcgccgaaat      180

cgtggccgag ttcttctcat tcggcatcaa cagcatttta tatcagcgtg gcatatatcc      240

atctgaaacc tttactcgag tgcagaaata cggactcacc ttgcttgtaa ctactgatct      300

tgagctcata aaatacctaa ataatgtggt ggaacaactg aaagattggt tatacaagtg      360

ttcagttcag aaactggttg tagttatctc aaatattgaa agtggtgagg tcctggaaag      420

atggcagttt gatattgagt gtgacaagac tgcaaaagat gacagtgcac ccagagaaaa      480

gtctcagaaa gctatccagg atgaaatccg ttcagtgatc agacagatca cagctacggt      540

gacatttctg ccactgttgg aagtttcttg ttcatttgat ctgctgattt atacagacaa      600

agatttggtt gtacctgaaa aatgggaaga gtcgggacca cagtttatta ccaattctga      660

ggaagtccgc cttcgttcat ttactactac aatccacaaa gtaaatagca tggtggccta      720

caaaattcct gtcaatgact gaggatgaca tgaggaaaat aatgtaattg taattttgaa      780

atgtggtttt cctgaaatca agtcatctat agttgatatg ttttatttca ttggttaatt      840

tttacatgga gaaaaccaaa atgatactta ctgaactgtg tgtaattgtt ccttttattt      900

ttttggtacc tatttgactt accatggagt taacatcatg aatttattgc acattgttca      960

aaaggaacca ggaggttttt ttgtcaacat tgtgatgtat attcctttga agatagtaac     1020

tgtagatgga aaaacttgtg ctataaagct agatgctttc ctaaatcaga tgttttggtc     1080

aagtagtttg actcagtata ggtagggaga tatttaagta taaaatacaa caaaggaagt     1140

ctaaatattc agaatctttg ttaaggtcct gaaagtaact cataatctat aaacaatgaa     1200

atattgctgt atagctcctt ttgaccttca tttcatgtat agttttccct attgaatcag     1260

tttccaatta tttgacttta atttatgtaa cttgaaccta tgaagcaatg gatatttgta     1320

ctgtttaatg ttctgtgata cagaactctt aaaaatgttt tttcatgtgt tttataaaat     1380

caagttttaa gtgaaagtga ggaaataaag ttaagtttgt tttaaatttg tcttaaaaaa     1440

aaaaaaaaaa aaa                                                        1453


<210>  1700
<211>  2400
<212>  DNA
<213>  homo sapiens

<400>  1700
ggcctgcagg gagcagccgc gagccggccg ggcgcgccga gcccgagccc cagccggagc       60

ggggcggggg agggaggagc cagagcggcc gccgcctctg ccggaggagc cgcggggccg      120

ccacactcgc cccccgcccc ccccgcgctc actcgcactc acacccgggc gcaggaggcg      180

ggcggcccgg gccccaccgg ccccccatgg acgcccccag cacggggcgc tgagaccccc      240

gcgtcgctgc ccagcccggt ccggcgcgcc acgccgaggg atctctggac aggacaagac      300

tccgaagcta ctcccccagc acacagcccg ggacccacaa acccagcttg cccccagccc      360

tcccacctgc cactccctgg cccctcccac cgcccgcccc ccttggggcg cagggcatgg      420

tgtgaaaggc caagtgctga ggcgggtatc atgggtgctg tgccctaggg cctgggtggc      480

agggggtggg tggcctgtgg gtgtgccggg ggggccagtg tgcccacccc agtctcttgg      540

cgtgctggag ggcatcctgg atggaattga agtgaatgga acagaagcca agcaaggtgg      600

agtgtgggtc agacccagag gagaacagtg ccaggtcacc agatggaaag cgaaaaagaa      660

agaacggcca atgttccctg aaaaccagca tgtcagggta tatccctagt tacctggaca      720

aagacgagca gtgtgtcgtg tgtggggaca aggcaactgg ttatcactac cgctgtatca      780

cttgtgaggg ctgcaagggc ttctttcgcc gcacaatcca gaagaacctc catcccacct      840

attcctgcaa atatgacagc tgctgtgtca ttgacaagat cacccgcaat cagtgccagc      900

tgtgccgctt caagaagtgc atcgccgtgg gcatggccat ggacttggtt ctagatgact      960

cgaagcgggt ggccaagcgt aagctgattg agcagaaccg ggagcggcgg cggaaggagg     1020

agatgatccg atcactgcag cagcgaccag agcccactcc tgaagagtgg gatctgatcc     1080

acattgccac agaggcccat cgcagcacca atgcccaggg cagccattgg aaacagaggc     1140

ggaaattcct gcccgatgac attggccagt cacccattgt ctccatgccg gacggagaca     1200

aggtggacct ggaagccttc agcgagttta ccaagatcat caccccggcc atcacccgtg     1260

tggtggactt tgccaaaaaa ctgcccatgt tctccgagct gccttgcgaa gaccagatca     1320

tcctcctgaa ggggtgctgc atggagatca tgtccctgcg ggcggctgtc cgctacgacc     1380

ctgagagcga caccctgacg ctgagtgggg agatggctgt caagcgggag cagctcaaga     1440

atggcggcct gggcgtagtc tccgacgcca tctttgaact gggcaagtca ctctctgcct     1500

ttaacctgga tgacacggaa gtggctctgc tgcaggctgt gctgctaatg tcaacagacc     1560

gctcgggcct gctgtgtgtg gacaagatcg agaagagtca ggaggcgtac ctgctggcgt     1620

tcgagcacta cgtcaaccac cgcaaacaca acattccgca cttctggccc aagctgctga     1680

tgaaggtgac tgacctccgc atgatcgggg cctgccacgc cagccgcttc ctccacatga     1740

aagtcgagtg ccccaccgaa ctcttccccc cactcttcct cgaggtcttt gaggatcagg     1800

aagtctaaag cctcaggcgg ccagagggtg tgcggagctg gtggggagga gcctggagag     1860

aaggggcaga gctgggggct gagggagacc cccccacacc ccttctctcc ttcctctcgt     1920

ccttggatag attcagctcc cacacacaca cccgcactgc ccaggtccct cctcagacct     1980

ccagccctgg gacagggcaa acaactgaac ttgctatgga aaggacagtg tgggaggctg     2040

ggggagctgt gtcctgcagt tcccaggacc ccatcctctc agaaggtagg ggaagggcgg     2100

gaggattgag aagggacaag ccaccttgac cgtaggggaa ggaggaatgt gggctggggg     2160

aagatgccct caactcaccc cctacacaca catgagagag agcccccacc cagttccttg     2220

gcctaggtct cccctccagg ctgagggcct ctctacttcc ccagatgcct gggtgcaaag     2280

aacggcttgg cttggctcct cctctggagg ttaaaattta tagtcattct aactgcactt     2340

tggaaaccaa gcaaggggag aagacaaatg aagaaaaact agacagagaa aaaaaaaaaa     2400


<210>  1701
<211>  2371
<212>  DNA
<213>  homo sapiens

<400>  1701
ccggagcctg cggcgggcgg ctgtgacggc cccggcgctg acggcggcgg ccgggggggc       60

ggtgtcgacg cccgcggcgc cggctggggc atcaccgcgg gcctcgaccc cgaaatggcg      120

ctgctggccg aacacttgct gaagccgctg cccgcggaca agcagatcga gaccgggccc      180

ttcctcgagg cggtgtccca cctgccgccc ttcttcgatt gccttgggtc cccagtgttt      240

actcccatca aggcagacat aagcggcaac atcacgaaaa tcaaagctgt gtacgacacc      300

aacccagcca agttccggac cctgcagaac atcctggagg tggagaaaga aatgtatgga      360

gcagagtggc ccaaagtagg ggccacactg gcgctgatgt ggctgaaaag aggcctccgc      420

ttcatccagg tcttcctcca gagcatctgc gacggggagc gggacgagaa ccaccccaac      480

ctcatccgtg tcaacgccac caaggcctac gagatggccc tcaagaagta ccatggctgg      540

atcgtgcaga agatcttcca ggcagcactg tacgcagcac cctataagtc tgacttcctg      600

aaagcgctct ccaaggggca gaatgttacg gaggaggagt gcctggagaa gatccgcctc      660

ttcctagtca actacacggc gaccatcgat gtcatctacg agatgtacac ccagatgaac      720

gctgagctta actacaaggt gtaggcatgc ccactgctgg acacgtcccc gactcgtggc      780

cacatggaga aacaggcaaa ccagaatcac tgtgaatcaa gtcggtgaac tgcccctggc      840

ctgtgtcccc cagagcagcc cagggtcctg ccagagtctg caggggacag ccctcgtttt      900

ttaagtcttt tttttttttt tttttggtct attctaaagg accagtaaat aatgatctta      960

cttccaaatc tccttggaat ttcacgacag cacagactga ctttatacct tcatttcagc     1020

gtggtaaaaa ccgattaaca cttctaatga gtcaagtcct agggtttttt ggttttgttt     1080

tgttgccaac gaggaacaca gctctggggg aatggtgtca tccacctcgc tttaaaaata     1140

agcacatgat ggctgggcac cgtggctcac gcctgtaatc ccagcacttt gggaggctga     1200

ggcgggtgga tcacctgagg tcgggagttt gagaccagcc tggccaacat ggtgaaaccc     1260

catcgctact aaaaatataa aaaattagct gggcatggtg gcgcacgcct gtagttccag     1320

ctactcagga ggctgaggca ggagaatcgc ttgaacccgg gaggtggagg ttgcagtgag     1380

ctgagatcgc accattgcac tccagcctgg gcaacaagag cgaaactctg tctcaaaaaa     1440

aaaaaaaaga ggtgggtgga ttacttgagg tcagggtttg agatcagcct gaccaacatg     1500

gtgaaaccct atctctacta aaaatataga attagccagg catggtagcg cacgcctgta     1560

atcccatctt cttgggaggc tgaggcagga gaatcgctag aaactgggag gtggaggtta     1620

cagtagccga gatcgcgcca ctgcattcca gcctgggcaa caaaagcgaa actctgtctc     1680

aaaaaagaaa aaaaagaaaa aaaagcacgt gaccttatga ggctctcgct gtattgttat     1740

tttaaggact ataaagagtt tgatttaaaa ttatgcaggg cccctatgtg ggatttttta     1800

aaaagcaaac tggtgtgtat tctcatgtgg tttgcacagc ccagcctcac agcactattg     1860

taaaccctgc tctttctgtc tcgctagaca gatttttttg tttgttttct tttttctggt     1920

tgttttttgt tgttgttgtt gttgttttac agctgaaacc aaccagcaag cccttgatga     1980

ccaagaggcg tttctttcaa agctataggg cacaaacaat tgaccataga tgactccgtt     2040

tgcattcttc tgcagaatta tttccttcag ggacagattt tccaacctaa gaaactacct     2100

accgtgtgta ttctcttgac ggggagagat gaacccttca gctgctaaga tccaagaaaa     2160

cgcctcactg ccttaacctt aactgttctt cctggcgcta aaaagagctg tattttttaa     2220

agtgctgggg caaacaaagc aaccccaaaa gagttgatgt gtgttttaaa agaaaaaacc     2280

caatgaggaa caattggaga tttttatgca gaaactaaat aatccttaat aaataaatct     2340

ctattttgga atcacaaaaa aaaaaaaaaa a                                    2371


<210>  1702
<211>  2371
<212>  DNA
<213>  homo sapiens

<400>  1702
ccggagcctg cggcgggcgg ctgtgacggc cccggcgctg acggcggcgg ccgggggggc       60

ggtgtcgacg cccgcggcgc cggctggggc atcaccgcgg gcctcgaccc cgaaatggcg      120

ctgctggccg aacacttgct gaagccgctg cccgcggaca agcagatcga gaccgggccc      180

ttcctcgagg cggtgtccca cctgccgccc ttcttcgatt gccttgggtc cccagtgttt      240

actcccatca aggcagacat aagcggcaac atcacgaaaa tcaaagctgt gtacgacacc      300

aacccagcca agttccggac cctgcagaac atcctggagg tggagaaaga aatgtatgga      360

gcagagtggc ccaaagtagg ggccacactg gcgctgatgt ggctgaaaag aggcctccgc      420

ttcatccagg tcttcctcca gagcatctgc gacggggagc gggacgagaa ccaccccaac      480

ctcatccgtg tcaacgccac caaggcctac gagatggccc tcaagaagta ccatggctgg      540

atcgtgcaga agatcttcca ggcagcactg tacgcagcac cctataagtc tgacttcctg      600

aaagcgctct ccaaggggca gaatgttacg gaggaggagt gcctggagaa gatccgcctc      660

ttcctagtca actacacggc gaccatcgat gtcatctacg agatgtacac ccagatgaac      720

gctgagctta actacaaggt gtaggcatgc ccactgctgg acacgtcccc gactcgtggc      780

cacatggaga aacaggcaaa ccagaatcac tgtgaatcaa gtcggtgaac tgcccctggc      840

ctgtgtcccc cagagcagcc cagggtcctg ccagagtctg caggggacag ccctcgtttt      900

ttaagtcttt tttttttttt tttttggtct attctaaagg accagtaaat aatgatctta      960

cttccaaatc tccttggaat ttcacgacag cacagactga ctttatacct tcatttcagc     1020

gtggtaaaaa ccgattaaca cttctaatga gtcaagtcct agggtttttt ggttttgttt     1080

tgttgccaac gaggaacaca gctctggggg aatggtgtca tccacctcgc tttaaaaata     1140

agcacatgat ggctgggcac cgtggctcac gcctgtaatc ccagcacttt gggaggctga     1200

ggcgggtgga tcacctgagg tcgggagttt gagaccagcc tggccaacat ggtgaaaccc     1260

catcgctact aaaaatataa aaaattagct gggcatggtg gcgcacgcct gtagttccag     1320

ctactcagga ggctgaggca ggagaatcgc ttgaacccgg gaggtggagg ttgcagtgag     1380

ctgagatcgc accattgcac tccagcctgg gcaacaagag cgaaactctg tctcaaaaaa     1440

aaaaaaaaga ggtgggtgga ttacttgagg tcagggtttg agatcagcct gaccaacatg     1500

gtgaaaccct atctctacta aaaatataga attagccagg catggtagcg cacgcctgta     1560

atcccatctt cttgggaggc tgaggcagga gaatcgctag aaactgggag gtggaggtta     1620

cagtagccga gatcgcgcca ctgcattcca gcctgggcaa caaaagcgaa actctgtctc     1680

aaaaaagaaa aaaaagaaaa aaaagcacgt gaccttatga ggctctcgct gtattgttat     1740

tttaaggact ataaagagtt tgatttaaaa ttatgcaggg cccctatgtg ggatttttta     1800

aaaagcaaac tggtgtgtat tctcatgtgg tttgcacagc ccagcctcac agcactattg     1860

taaaccctgc tctttctgtc tcgctagaca gatttttttg tttgttttct tttttctggt     1920

tgttttttgt tgttgttgtt gttgttttac agctgaaacc aaccagcaag cccttgatga     1980

ccaagaggcg tttctttcaa agctataggg cacaaacaat tgaccataga tgactccgtt     2040

tgcattcttc tgcagaatta tttccttcag ggacagattt tccaacctaa gaaactacct     2100

accgtgtgta ttctcttgac ggggagagat gaacccttca gctgctaaga tccaagaaaa     2160

cgcctcactg ccttaacctt aactgttctt cctggcgcta aaaagagctg tattttttaa     2220

agtgctgggg caaacaaagc aaccccaaaa gagttgatgt gtgttttaaa agaaaaaacc     2280

caatgaggaa caattggaga tttttatgca gaaactaaat aatccttaat aaataaatct     2340

ctattttgga atcacaaaaa aaaaaaaaaa a                                    2371


<210>  1703
<211>  5031
<212>  DNA
<213>  homo sapiens

<400>  1703
acgtgaccta ggctgcggcg gcggcgtgct gcgggctctg tggcgggagc gaggccgacg       60

ggcggggccg cgcggccgcg tgacgcgaag cgttcgagag cgcgcgtcgt ggaacgtctt      120

ggttgccacg gcaagcgcgc gcgcgaggcc ttgggaacct cgggaccggc ccccggcgag      180

cgcagcggcg cccagtgtaa gggagtggga gctggtccgt gccgcggcgg ccgcgcaggg      240

agctctcgag gcaacgccgg ggcgcccgag gtctggaagg cgcagaaatg gagcaagagc      300

cacaaaatgg agaacctgct gaaattaaga tcatcagaga agcatataag aaggcctttt      360

tatttgttaa caaaggtctg aatacagatg aattaggtca gaaggaagaa gcaaagaact      420

actataagca aggaatagga cacctgctca gagggatcag catttcatca aaagagtctg      480

aacacacagg tcctgggtgg gaatctgcta gacagatgca acagaaaatg aaagaaactc      540

tacagaatgt acgcaccagg ctggaaattc tagagaaggg tcttgccact tctctgcaga      600

atgatcttca ggaggtgccc aagttatatc cagaatttcc acctaaagac atgtgtgaaa      660

aattaccaga gcctcagtct tttagttcag ctcctcagca tgctgaagta aatggaaaca      720

cctcaactcc aagtgcaggg gcagttgctg cacctgcttc tctgtcttta ccatcacaaa      780

gttgtccagc agaagctcct cctgcttata ctcctcaagc tgctgaaggt cactacactg      840

tatcctatgg aacagattct ggggagtttt catcagttgg agaggagttt tataggaatc      900

attctcagcc accgcctctt gagaccttag ggctggatgc agatgaattg attttgatac      960

caaatggagt acagattttt tttgtaaatc ctgcagggga ggttagtgca ccttcgtatc     1020

ctgggtacct tcgaattgtg aggtttttgg ataattctct cgatacggtt ctaaaccgtc     1080

ctcccgggtt tcttcaggtt tgtgactggt tatatcctct agttcctgat agatctccgg     1140

ttctgaaatg tactgcggga gcctacatgt ttcctgatac aatgctacaa gcagcaggat     1200

gctttgtggg ggtcgtcctg tcctctgagt taccagagga tgatagagag ctctttgagg     1260

atctgttaag gcaaatgtct gaccttcggc tccaggccaa ctggaacaga gcagaagaag     1320

aaaatgaatt ccaaatccct ggaagaacta gaccctcctc tgaccaacta aaagaagcct     1380

ctggcactga tgtgaaacag ttggaccaag gcaataagga tgtacgtcat aaaggaaaac     1440

gtggaaaaag ggctaaagat acttcaagtg aagaagttaa cctgagtcac attgtaccat     1500

gtgagccagt tccagaagaa aagccaaaag aattacctga atggagtgaa aaagtggctc     1560

acaacatttt gtcaggtgct tcctgggtga gttggggttt agtcaaaggt gctgagatta     1620

ctggtaaggc aatccagaaa ggtgcttcta aactccgaga gcggattcaa ccagaagaaa     1680

aacccgtgga agttagtcca gctgtcacca agggacttta tatagcgaag caagctacag     1740

gaggagcagc aaaagtcagt cagttcctgg ttgatggagt ttgcactgta gcaaattgcg     1800

ttggaaaaga actagctcca catgtcaaga agcatggaag caaacttgtt ccagaatctc     1860

ttaaaaaaga caaagatggg aaatctcctc tggatggtgc tatggttgta gcagcaagta     1920

gtgttcaagg attttcaact gtctggcaag gattggaatg tgcagctaaa tgcatcgtta     1980

acaatgtttc agcagaaact gtacaaactg tcagatacaa atacggatat aatgcaggag     2040

aagctaccca ccatgcggtg gattctgcgg tcaatgttgg cgtaactgcc tacaatatta     2100

acaacattgg tatcaaagca atggtgaaga aaactgcaac acaaacagga cacactctcc     2160

ttgaggacta tcagatagtt gataattctc agagggaaaa tcaagaagga gcagcaaatg     2220

tcaacgtgag aggggagaag gatgagcaga cgaaggaagt aaaggaggca aagaagaaag     2280

ataaatgatg aagtgctggg aatcacttat accaaagcct tatgaaatgg atgaaatttt     2340

gttaaatagg caaatgtgga attcctcaca gattaaccag tattttttaa atgtattcat     2400

tcctacaaat taactttcat aaattttatg gcatgtcttc tatttaaaag gaaaagaata     2460

agtattcttg catctggcct tagaaatgtg aagttatatt ctcaagttta tttttttcca     2520

agtgtagcta aaatattttt gcaggtaaaa taaagctgat agtacatgtg ttgttcaaac     2580

cttgttaaac ctaatattga actattttta tatctgctgt ctttcagaag gcaaatagga     2640

aactatatat ttgcttaaaa attggcattt agtaacctta attcttttta tagaaggaat     2700

gacttaaagt attgtcccct ctttttgcac taattgtgga tttttttaga tgcttctcaa     2760

aattttcagt gtgtaagcta aacaaaaact aaaactaaga attctcaaaa aaacttgttc     2820

aaaacaggga aagactgatg aaaagtaaaa tggactactt ttgtaactta cctgtttgtt     2880

aggaaatgga atggtctctt tgatttaaaa taaataaaaa tagattatta cgtcttttgt     2940

attgagactg tattgttatg agcctaggaa atttgggaac atgattgtat tgtattaaaa     3000

ttcgaagtga ttattatcag cttaattgga ttaaaaaagt acttcaagaa attattttat     3060

catatctgct tctgtttttc caaaaggtta aaacttgtaa aaaaaatata tataaacaat     3120

tgagtttact aatggtaaac atttttattc tgggattcgg tcattggaat ttatattaaa     3180

agacaagtta ttaaaaagga aaggttctat tcataatcag ggtaaagaat atgaaaacct     3240

tagacgtaat ccatggtgga taggcattat ggtttccact ttggcagaag gcagactatt     3300

cacagcccta tttacttaca taggctaaaa aactatgtaa ctaaatacct aatggtattt     3360

aatttttgtt tattgaattt aagagattgg tattagtttt catagctgta gtccattcta     3420

ataatttctg atcttctagt ggctacttaa ttagacatta tttgaagctg tctgaagaat     3480

gcactttatg aattaaaaaa ctgaattgcc tgacctcgtt atcacatgag cttatatttt     3540

gggaacacat agaactgatg gaggcttttc ctaaggccaa ggataatgta ctagttgtta     3600

aaatggaaat aaaagtgaag tggtaaatag cttacagaca gtctatgctt tgtttaagaa     3660

atggaatggc acttcatata ttctcatttg tgggagctaa aaattacaat aatcaaactt     3720

aaggagatag agagtagaat gatggttacc agaggctggg aggcattgaa gggatgggga     3780

gggaagtgag gttgattaat gggtacgaaa atatagttag aacgaatttg ttgtagtatt     3840

tgatagccca acagggtgac tacagtcaac aataacttta tacatttaaa aataaaagag     3900

tgtaattggg acgtttgtaa cacaaatgaa tgcttgaagc agtagataca ccctgatgta     3960

attattataa atcgcatacc tgtatcaaaa tatctcatgt atcccataaa tatatacacc     4020

taccatgtac ccataaaaat ttaaaaagaa atggaatggc aaataatgga acataaactt     4080

taaacagtta gctttgacca gaggtcagca aatatcctcc atgggctaaa tccagatgtc     4140

cacctgtttt cataaataac gttttattgg agcatagctg tacccatttg tttacatatt     4200

ggctatggct gctgtctagt tcaacgtgag agttgaatag ttgcatcaga gagtatatgg     4260

tccacaagcc taacttattc actctctggc cctttgcaga aaaagtgtgc tgccttagtc     4320

tatagaaaat ggacttttcc caccattcac tgactcatta ggagataggc atcttctaaa     4380

gatttttttt atattgtgta atgattgata tatagataaa attatatatt acttgtaagg     4440

tatgatgaat aacaacactt aaaaactcat cacacctaaa gacatggaaa gctgccaatt     4500

acctatatgt atgttcttcc tattttctta cctctttccc catgtcattt tttattgttc     4560

cttgccattt tttaatcaca catgtatgtt ctccaaacat actgtttcat tttttgaagc     4620

tttctacata tagtgtctga atgtgaagtc ttactcaact tgcttttttg agtttatgtt     4680

taaaattcat tcttgcgctt atatgcatgg atggtttact tgctctatag tattctgtgt     4740

gagtatacca caatttaagt gttcattttc ctatcagttg acatttgttt ttagtttttg     4800

ttggtagaaa cagtacactc aaaacatcct tgactgtccc ctggtacaca tatgcaagag     4860

actttatgcg taagagtgga gttgttggct tgtcaagttt tgcaaaataa tgccaggtat     4920

tttccaaaat gatgatattc tcttgagtat tacttccctt tgcaatgttt ttattgttaa     4980

tgtagcatat ataaaaaagt atctcataat tttaaaaaaa aaaaaaaaaa a              5031


<210>  1704
<211>  5031
<212>  DNA
<213>  homo sapiens

<400>  1704
acgtgaccta ggctgcggcg gcggcgtgct gcgggctctg tggcgggagc gaggccgacg       60

ggcggggccg cgcggccgcg tgacgcgaag cgttcgagag cgcgcgtcgt ggaacgtctt      120

ggttgccacg gcaagcgcgc gcgcgaggcc ttgggaacct cgggaccggc ccccggcgag      180

cgcagcggcg cccagtgtaa gggagtggga gctggtccgt gccgcggcgg ccgcgcaggg      240

agctctcgag gcaacgccgg ggcgcccgag gtctggaagg cgcagaaatg gagcaagagc      300

cacaaaatgg agaacctgct gaaattaaga tcatcagaga agcatataag aaggcctttt      360

tatttgttaa caaaggtctg aatacagatg aattaggtca gaaggaagaa gcaaagaact      420

actataagca aggaatagga cacctgctca gagggatcag catttcatca aaagagtctg      480

aacacacagg tcctgggtgg gaatctgcta gacagatgca acagaaaatg aaagaaactc      540

tacagaatgt acgcaccagg ctggaaattc tagagaaggg tcttgccact tctctgcaga      600

atgatcttca ggaggtgccc aagttatatc cagaatttcc acctaaagac atgtgtgaaa      660

aattaccaga gcctcagtct tttagttcag ctcctcagca tgctgaagta aatggaaaca      720

cctcaactcc aagtgcaggg gcagttgctg cacctgcttc tctgtcttta ccatcacaaa      780

gttgtccagc agaagctcct cctgcttata ctcctcaagc tgctgaaggt cactacactg      840

tatcctatgg aacagattct ggggagtttt catcagttgg agaggagttt tataggaatc      900

attctcagcc accgcctctt gagaccttag ggctggatgc agatgaattg attttgatac      960

caaatggagt acagattttt tttgtaaatc ctgcagggga ggttagtgca ccttcgtatc     1020

ctgggtacct tcgaattgtg aggtttttgg ataattctct cgatacggtt ctaaaccgtc     1080

ctcccgggtt tcttcaggtt tgtgactggt tatatcctct agttcctgat agatctccgg     1140

ttctgaaatg tactgcggga gcctacatgt ttcctgatac aatgctacaa gcagcaggat     1200

gctttgtggg ggtcgtcctg tcctctgagt taccagagga tgatagagag ctctttgagg     1260

atctgttaag gcaaatgtct gaccttcggc tccaggccaa ctggaacaga gcagaagaag     1320

aaaatgaatt ccaaatccct ggaagaacta gaccctcctc tgaccaacta aaagaagcct     1380

ctggcactga tgtgaaacag ttggaccaag gcaataagga tgtacgtcat aaaggaaaac     1440

gtggaaaaag ggctaaagat acttcaagtg aagaagttaa cctgagtcac attgtaccat     1500

gtgagccagt tccagaagaa aagccaaaag aattacctga atggagtgaa aaagtggctc     1560

acaacatttt gtcaggtgct tcctgggtga gttggggttt agtcaaaggt gctgagatta     1620

ctggtaaggc aatccagaaa ggtgcttcta aactccgaga gcggattcaa ccagaagaaa     1680

aacccgtgga agttagtcca gctgtcacca agggacttta tatagcgaag caagctacag     1740

gaggagcagc aaaagtcagt cagttcctgg ttgatggagt ttgcactgta gcaaattgcg     1800

ttggaaaaga actagctcca catgtcaaga agcatggaag caaacttgtt ccagaatctc     1860

ttaaaaaaga caaagatggg aaatctcctc tggatggtgc tatggttgta gcagcaagta     1920

gtgttcaagg attttcaact gtctggcaag gattggaatg tgcagctaaa tgcatcgtta     1980

acaatgtttc agcagaaact gtacaaactg tcagatacaa atacggatat aatgcaggag     2040

aagctaccca ccatgcggtg gattctgcgg tcaatgttgg cgtaactgcc tacaatatta     2100

acaacattgg tatcaaagca atggtgaaga aaactgcaac acaaacagga cacactctcc     2160

ttgaggacta tcagatagtt gataattctc agagggaaaa tcaagaagga gcagcaaatg     2220

tcaacgtgag aggggagaag gatgagcaga cgaaggaagt aaaggaggca aagaagaaag     2280

ataaatgatg aagtgctggg aatcacttat accaaagcct tatgaaatgg atgaaatttt     2340

gttaaatagg caaatgtgga attcctcaca gattaaccag tattttttaa atgtattcat     2400

tcctacaaat taactttcat aaattttatg gcatgtcttc tatttaaaag gaaaagaata     2460

agtattcttg catctggcct tagaaatgtg aagttatatt ctcaagttta tttttttcca     2520

agtgtagcta aaatattttt gcaggtaaaa taaagctgat agtacatgtg ttgttcaaac     2580

cttgttaaac ctaatattga actattttta tatctgctgt ctttcagaag gcaaatagga     2640

aactatatat ttgcttaaaa attggcattt agtaacctta attcttttta tagaaggaat     2700

gacttaaagt attgtcccct ctttttgcac taattgtgga tttttttaga tgcttctcaa     2760

aattttcagt gtgtaagcta aacaaaaact aaaactaaga attctcaaaa aaacttgttc     2820

aaaacaggga aagactgatg aaaagtaaaa tggactactt ttgtaactta cctgtttgtt     2880

aggaaatgga atggtctctt tgatttaaaa taaataaaaa tagattatta cgtcttttgt     2940

attgagactg tattgttatg agcctaggaa atttgggaac atgattgtat tgtattaaaa     3000

ttcgaagtga ttattatcag cttaattgga ttaaaaaagt acttcaagaa attattttat     3060

catatctgct tctgtttttc caaaaggtta aaacttgtaa aaaaaatata tataaacaat     3120

tgagtttact aatggtaaac atttttattc tgggattcgg tcattggaat ttatattaaa     3180

agacaagtta ttaaaaagga aaggttctat tcataatcag ggtaaagaat atgaaaacct     3240

tagacgtaat ccatggtgga taggcattat ggtttccact ttggcagaag gcagactatt     3300

cacagcccta tttacttaca taggctaaaa aactatgtaa ctaaatacct aatggtattt     3360

aatttttgtt tattgaattt aagagattgg tattagtttt catagctgta gtccattcta     3420

ataatttctg atcttctagt ggctacttaa ttagacatta tttgaagctg tctgaagaat     3480

gcactttatg aattaaaaaa ctgaattgcc tgacctcgtt atcacatgag cttatatttt     3540

gggaacacat agaactgatg gaggcttttc ctaaggccaa ggataatgta ctagttgtta     3600

aaatggaaat aaaagtgaag tggtaaatag cttacagaca gtctatgctt tgtttaagaa     3660

atggaatggc acttcatata ttctcatttg tgggagctaa aaattacaat aatcaaactt     3720

aaggagatag agagtagaat gatggttacc agaggctggg aggcattgaa gggatgggga     3780

gggaagtgag gttgattaat gggtacgaaa atatagttag aacgaatttg ttgtagtatt     3840

tgatagccca acagggtgac tacagtcaac aataacttta tacatttaaa aataaaagag     3900

tgtaattggg acgtttgtaa cacaaatgaa tgcttgaagc agtagataca ccctgatgta     3960

attattataa atcgcatacc tgtatcaaaa tatctcatgt atcccataaa tatatacacc     4020

taccatgtac ccataaaaat ttaaaaagaa atggaatggc aaataatgga acataaactt     4080

taaacagtta gctttgacca gaggtcagca aatatcctcc atgggctaaa tccagatgtc     4140

cacctgtttt cataaataac gttttattgg agcatagctg tacccatttg tttacatatt     4200

ggctatggct gctgtctagt tcaacgtgag agttgaatag ttgcatcaga gagtatatgg     4260

tccacaagcc taacttattc actctctggc cctttgcaga aaaagtgtgc tgccttagtc     4320

tatagaaaat ggacttttcc caccattcac tgactcatta ggagataggc atcttctaaa     4380

gatttttttt atattgtgta atgattgata tatagataaa attatatatt acttgtaagg     4440

tatgatgaat aacaacactt aaaaactcat cacacctaaa gacatggaaa gctgccaatt     4500

acctatatgt atgttcttcc tattttctta cctctttccc catgtcattt tttattgttc     4560

cttgccattt tttaatcaca catgtatgtt ctccaaacat actgtttcat tttttgaagc     4620

tttctacata tagtgtctga atgtgaagtc ttactcaact tgcttttttg agtttatgtt     4680

taaaattcat tcttgcgctt atatgcatgg atggtttact tgctctatag tattctgtgt     4740

gagtatacca caatttaagt gttcattttc ctatcagttg acatttgttt ttagtttttg     4800

ttggtagaaa cagtacactc aaaacatcct tgactgtccc ctggtacaca tatgcaagag     4860

actttatgcg taagagtgga gttgttggct tgtcaagttt tgcaaaataa tgccaggtat     4920

tttccaaaat gatgatattc tcttgagtat tacttccctt tgcaatgttt ttattgttaa     4980

tgtagcatat ataaaaaagt atctcataat tttaaaaaaa aaaaaaaaaa a              5031


<210>  1705
<211>  6149
<212>  DNA
<213>  homo sapiens

<400>  1705
cattttgcta ggcagcggca gtggcggcgg cagcggcggc tggagcctct gattgggttt       60

cggagtccgg tactggagcc aatcagcgcg ggcagcgaac cgggggagcg aggcacggag      120

tgtacctcac agccttctag gatctccaga gtggacagga atctcacttg gagggaccat      180

ggagcagtat acagcaaaca gcaatagttc gacagagcag attgttgtcc aggcaggaca      240

gattcagcag caggtccaag ggcagccatt aatggtgcag gtcagtggag gccagctaat      300

cacatcaact ggccaaccca tcatggtcca ggctgtccct ggtggacaag gtcaaaccat      360

catgcaagta cctgtttctg gaacacaggg tttgcagcaa atacagttgg tcccacctgg      420

acagatccag atccagggtg gacaggctgt gcaggtgcag ggccagcagg gccagaccca      480

gcagatcatc atccagcagc cccagacggc tgtcactgct ggccagactc agacacagca      540

gcagattgct gtccagggac agcaagtggc acagactgct gaagggcaga ccatcgtcta      600

tcaaccagtt aatgcagatg gcaccattct ccagcaagtt acagtccctg tttcaggcat      660

gatcactatc ccagcagcca gtttggcagg agcacagatt gttcaaacag gagccaatac      720

caacacaacc agcagtgggc aagggactgt cactgtgaca ctaccagtgg caggcaatgt      780

ggtcaattca ggagggatgg tcatgatggt tcctggggct ggctctgtgc ctgctatcca      840

aagaatccct ctacctggag cagagatgct tgaagaagag cctctctacg tgaatgccaa      900

acaataccac cgtattctta agaggaggca agcccgagct aaactagagg cagaagggaa      960

aattccaaag gagagaagga aatacctgca tgagtctcgg caccgtcatg ccatggcacg     1020

gaagcgtggt gaaggtggac gatttttctc tccaaaggaa aaggatagtc cccatatgca     1080

ggatccaaac caagccgatg aagaagcaat gacacagatc atccgagtgt cctaacccca     1140

cgccatgtga tggagctgat caaggtcatg tttctcactg ttccaggaaa ttgatcaact     1200

cttccaatgg gacattgatg atcacattct gccctttact acaggacaga aaccacttag     1260

tttttaataa gtggctcagt attacaattg cagcgatgcc tggcaaattg aagttgcaag     1320

cctttgtctt actctttcag tcaggaccta tttcagactg ttgatgacat tgacatttca     1380

tggattcgga tgatgcaagg agacacatgc caccccagca gtacacaaag cacttacctt     1440

gactggtgaa gtcagccagc catctcagca gggaagaaca accttctcaa ccaaaactgc     1500

aatcaggaaa gcagcagccc actccttccc atggaatcta gacagcattt atccctctgg     1560

tgggggaatc tcacactgac taactgaatg gacgctttgt attcagagat ggcttccagg     1620

caaggaagtt ctatcttgtg atacggaaac aataaattcc tgagatacat tcttccaatc     1680

tgtggtaata ataagaattc ctctctgccc agatggtagg ttgatatttc tggactctag     1740

ccaagaaaaa gctaattctg gggatagaat gataaaagac tcaagcacta aaaatataca     1800

ttgccgaatc tctttttcta gctttgaaaa gttgtggcct gcttgtccct ctgttgactg     1860

gtcatctgga ccatcgtact tgctgtggct acttctaaga caatgtagag ggttattaaa     1920

ccttgaaact gcctttccta agtagagaac aagactattc aacaacttct ttgctgaagc     1980

actgaggaga tttgtaatac tcctaaagga agggccaaac tagagatttt caatcataga     2040

ctttgtgaca gcatttgggg aactaaaaga ttcatgtgtt tcagcctagt gggagagagt     2100

gggggagagg aagagagaga gagagcatgt atacccgtat gttatcatag agcacgattc     2160

tccagtggat ggatacctgg aatggatcat taagatgaag agagtaattc acatttactc     2220

tagaaccttt aacaagcact gaaaggaaga agcctgagat ttgatccttg acaatttctg     2280

gaaagcactg gtcagtcaca ctgtcctgga cagagtccaa gttacccact aaagcttgag     2340

gtggatgttg gcttcactcc tgcagcacaa tgctggccct agaaagcgag cattttcatt     2400

cttcccatgg cagctgattc tttggtgcca gttttcatgt tttctccata ggccttgtgc     2460

agaaaggttt tctcattgca tccatactgt gagaataaac tgcagactga aagaaacatg     2520

cctgcagggt caggaactgg gccactgttc ccagaacggg ttgtgcctca gaaatctatt     2580

tctcttttag atgttgaacc ctgagagaac taagatgata tttcagaaga gttggctgcc     2640

ttctctggaa acaaggaaaa cccaataatt ccgaggaaca ttgggggtta aataccaaga     2700

ataaaaattg gttcttcttt gacttcagct taactgtatt aagacagaaa ttaagccctc     2760

taaaaacacc acaaagagag atgattgtaa tgatagaaat agaggtacag agctatgcaa     2820

aggaaacagg aagtgaaata ttcctagtcc cagggatctg gtaatcgctc ctggcttcca     2880

gatgtcaaag gactgatcct ttggtaagct cactagaaac ttctagctct acaagagttt     2940

gggatattaa tgttattcag taagtcccaa gtttttcaga gaatagatta ctaacaatga     3000

ggaatttata ttccttggtt aatttaggag tctaagatgc agagttcaga aagaaattac     3060

tcagacctaa ctttgagtgc ttaagctgcc aacagttaga agatgctatt tatttgtgtc     3120

tgtaagtttg tacatagtaa tgccagcctt gttgctgaat tttttatttg gggggagatg     3180

actttgaatt ttgtttgaaa tgcttcagtt gtcattttgt cattgcattt caaatagctc     3240

atgacccttt tcttgtggtc actttggcac accatagtag cccacaaagt gggggcaggg     3300

tattgacatt tggatttttt ctttgatact agttctttta ttcattttta tttgtgactg     3360

tagtgataac tttacagatg gagaaagagt gaatggatga atgaataatt ggtttaatgc     3420

ctagttatgc aacttgagtg cttttttttt tttttgcagg ataattttaa gtgtatatat     3480

tttaactgca ctggtacatt gaacatgtca gtgtcgatgc cactggacca acagagcatt     3540

ttgtggctat agggtgcctg ataataatgt cttgattttt ctttgggatt caactatatc     3600

gaaggttttt cccccagcag tatgggggcg tacaggtgat cgatcattaa tgtcattgca     3660

attgttattt tttaaaataa atttataaaa ataaccgaaa agtaatgtga cttttgagga     3720

atctgcaact cctgggttct agtttgtgtt tccagtgttg aaattttgat ctcccccgac     3780

aagacttgtc tgcatggacg gtgtctctgt aaacagtatc aaacttgtaa tgtctgagcc     3840

tcttagcttt atctcccctt aatttcttcc cttttggccc ttccaccctg ttgaggagat     3900

tttttctgtc acctgcaggc tgatcataca tttgatgcta ctactgaaag tgtttatcaa     3960

aatgtgatga agtaattcca tgaggaaaat tagccgttat cacaaaaaca gccttaagta     4020

ttgtagaatt tcaggtagtg aagatgtact atttacgttt tgttagattt tgttttggca     4080

gaagaccaaa acaaaagtac ttttctgatt gttaaaaatc cacagcatgc tcaccttgtt     4140

actgttttac cttacggtcg ctgggaatct aagcaacaaa gactagaagc ctccgatatg     4200

ccattatcaa cacacaagag acaaacagcc cgaggaagca ctcaatgatg agagcagtag     4260

acctgccctg gcagatgaga gaggagaaac tctccacaat gaaggaaaag cactgacagt     4320

atttgatagc tttagtcaaa ctgtgcttga gtttggctta gatttatgcc agtggaacct     4380

gtccttacca aattcagaga tgacccaaga ttctactctg tggtatgagg gaaagacctc     4440

tcgatattta tctcacacca acggctttat cgtaggagcg tcttcgcctc ccccgtttcc     4500

agtagaaaag acagctttgc tcctttgaaa gcgcagaccg ccgcacctcc agccccttct     4560

ccccggggaa gtaggccccg ctaagaatgt gggaaggtgg tggggcggcg actgaagtcg     4620

cttccgattg gcgttgtccc aaggaagcct gcgcggattg atcggcggca ggcctccaat     4680

agagcctgct aggcggattg gctgctacgc ggctgggccc tgtttccggt acctaggcgg     4740

gcagccatgg tgaccggcga gcggcatgcg acgccgcctc tgtggcctgt ggaggcccgc     4800

ttggcggcgc tgcttcccga cctactggtc tttcggaagc ctcggggatg ggaacccgag     4860

ctcgccacgg cccagggcgt cctcctaggc gtccatgtga cgggtgaggg cgacggccgg     4920

cacttgcact taagtctcct ggcctgcggg agaggcggcc gttgggtcta agcccctgga     4980

ggcctcgacg gttacaggcc tagcctcccg cgagctaagg cacagtttaa cttcgtgctg     5040

cggcttcctt aggaaacttt gagtatcttc gttttagcgt gggaggacat cttttgggat     5100

gaaccggctc agtccttgag ctcaccccaa agatgatgaa attgaaactc agaggaaagg     5160

atttttacag gaccacgccc cgggctttga acccgttttt cccaaccccg agcattttct     5220

attaagcgtt ctgtttcaat tattttattc gttcagttaa ttcgttcttg gcgtcataag     5280

tatatgcccg ccgttgttct ggccgtagct atctagcagc cactccgcga gtcgttcatt     5340

taacaaatac ttactctgtg tcagggatat gaagatgggt aataccaggt gcctgtcctc     5400

actgtgtgag tggttctcta gccagacatg aggagggatc ctattgtttc ccatagctag     5460

gcagcctaag agagtagggg aaagagctgg ctccagatga aaagggcacc atctccagct     5520

cttggaagca gagagggtgg tcctttggat tcccagtggc agcagcaacc aacctggccc     5580

ttagtagttt ctaagttaca ccatgttaat ggataaagga attactcagc ttgaagggat     5640

ctgtttcctt tacactggcc tgatgtgtgg ggagaaaggg gccaaaaagt ttaggatttg     5700

gagttaacat cgtaatttct gctttgttgg tcagggttta cagcattaat ggacaggttc     5760

accctgacct acaagtcgga acgtgacatg gacaaactgg cccatatctt cagttattac     5820

attagtgaca tcgtggagcg tgagtgatca ttgtagggta acaaggtgtg gtgctgggct     5880

cctgggggtt tataaaagaa gggggccaga agtactttaa aacaggtacc aaagggtcat     5940

tcctttagca tcattcatct ttggtttctt caagttgcca ctgaaaagct agacctttgc     6000

ctattatctg ctaatctacc cagtctcaca ttctattgac tcattgttca aagggggggc     6060

aggaggagct aatttccttt gcacatttgt attttatttc aaaataaagt attctcttct     6120

aacaataacg taaaaaaaaa aaaaaaaaa                                       6149


<210>  1706
<211>  4014
<212>  DNA
<213>  homo sapiens

<400>  1706
gttgcggtgg ccaatagacg cattcggaac atcggcggct gcccgggtga cttggttata       60

tgtcacagaa taacattcga gaatgggaca tggaatgagg cgacggcccc agcaagcccc      120

agcagcccca gccccagccc caggcccagc agcagcagca gcagcccctg ctctcccgcc      180

gcccggagag gctctgcagc catgaagcca accgtcccga gccttcaata ccccaggtcc      240

caaactacag gctgtcgatg acgatcccag actggctcca ggcgatccag aattacatga      300

agaccctaca atataatcac acagggaccc agttctttga aattaggaaa atgagaccgc      360

tgagtgggtt aatggaaaca gcaaaagaaa tgacccgaga gtccttgcct atcaaatgcc      420

ttgaagctgt catcctgggc atctacttaa ccaatgggca gccttccatt gagcggttcc      480

ccatcagctt taaaacctac ttctcaggaa actactttca ccacgttgtg ctggggattt      540

actgcaatgg ccgctatggc tcattgggca tgagccgcag ggctgagctg atggacaagc      600

cattgacttt tcggactctg agtgacctca tctttgactt tgaggactct tacaagaaat      660

acctgcacac agtcaagaag gtcaagattg ggctgtacgt cccccatgag cctcatagct      720

tccagcccat tgagtggaag cagctggtcc tcaacgtctc aaagatgctg agggctgaca      780

taaggaagga gctggagaaa tatgccaggg acatgagaat gaagatcctg aaacctgcaa      840

gtgcccactc tccgacccaa gtgagaagcc ggggaaaatc cctgtccccc agaaggagac      900

aggcaagccc cccgaggagg ctcggccggc gagagaagtc gcctgcactg cctgaaaaga      960

aggtggctga tctgagcact ctgaatgaag tgggctatca aatccgaatt tagccaagcc     1020

ataccggcca gcaagagggt ttctgtggtg cttctctctg cactttaccc agcatcttca     1080

ggaggaactg caactattta ttaagaactt gtgaatttta tttttaagga ttcacctgga     1140

aatagaatct gagtgggtgg taaccattag ctttaaaaaa ttcactaaaa ggcaccatga     1200

aaaggctgaa gtaataagcc ccactggggt tggactatgt ccctcactca agatcttaag     1260

gataaccgta actgaagttt tatatttttc catttaccta ctttctttta cttgctttga     1320

acattatgcc tcaccaatag taaatgttca tgaaataatc tcttgaactt ttggtatagt     1380

aaggtaactc taacagtatt actgtctttt tcagcaataa cagaaagcaa aaatgggtgg     1440

gtttttttta agcagttatt acctcagcat tttgacatca gatatgcaaa cttaatggcg     1500

ttttgttttt ttatattcta tttgtattct ttccccagta tttcccatgg ggatctccac     1560

aagtttggag ttttttcctg gtgcacacac gtgaggagat ttaaggtact atatgcaagt     1620

gttttactaa aaagcactga aattcttctg gcaatacaag aaccattttc aggatcttgg     1680

agttacttcc ttcttaatct ttcttaaagc attcactgat gtttttgttt tttcaaaatg     1740

aaacaaaaat atcacattga gaagctagtc tatgttctgt cactaacatt taaactttgc     1800

agactctaac aaaaagcaca agaggtcacg tactattata caaatttagc ggtactggat     1860

ttacctctga cattaacaca ctcaggcaga gaccaggagt gatcagcagg tcttcagaac     1920

caaaaaacct ttctgttcac atttcatctg atttttaaac tgaggcaggc tttgattctt     1980

ctgaaggatg ccaagaatca aactaaggga ggactcactg ttaaagatgt gttctgatgt     2040

cttatattaa gaccaaatgt gacatgatgt gattatcttc cagtactttg cttttaggta     2100

ccatttcatg acattttagg aatgagtatt ggaaaatata aagaattaga aaagcagcac     2160

ttttttttta atggaaaagt cttcggtcca gtgttacacc ttatagtgta attcagtccc     2220

taagcacaga atgaatgtct ggcctgcata tggtagttac agtgtaacct ctggctgcag     2280

accacacagg acaaccctaa cagcctagtc ttgtatggtg taaatatcaa gagtacagct     2340

tcaatttcat ttgctttatc ttagcaacaa tgccaactca ggagagcaga cggccgattt     2400

cagtgaagtc tggtagtcaa cagatgttat ttcagtctca gtgcatctcc tctggctttc     2460

tttgactgaa ggtgtttata ggaaggaagt taaaaaaaaa aaaagctcat tgagattctt     2520

taccaattct ttacaagatt tctgggggtg acagggaaag caaaaggact tcaaagcaaa     2580

agggtgcaca agagcttact tcaccctgaa aatcagtatt attaatgaaa agtactgttt     2640

tcttaaagaa gtcgaatgtc ctttagatga acaagaccaa gtatacatct ccattagatt     2700

aaaatgtagc acagggttaa aaattatcag tttaatctct ttaagaacag tattatcaga     2760

gtttaaaatg agttagctct gtttatctac acacagcaaa cccattcgca gcctcttggc     2820

cacatgtatt cagatgtttg aaatagtgaa tcatttcatt ttcattctaa aacaatactg     2880

acttagccat ataccttctg tttgtcaatc tgaaacttgc ttacatctaa taagtagacc     2940

tcttataaca ctgcaaccat tctaagagtt ggaatttatt tttgccaagt attaagtact     3000

gttacatcta aaatacagaa tgtcaaatgg ttgcatagct tgtttcccac aacaaggagg     3060

aaaagaacag gaatacaaac tctgtaatat gctgataaag aagccttaga actgccaact     3120

ggcttgatgg ttcaattagt aagctaattt ctcccacacc cgctccttga tttttagact     3180

aattttccca aagcaaggtt tagtcacaca aacttgaaag tacatttaaa atgttcttag     3240

ttgtcatcct acttttattg cctatggaat atgctaattt ctaaaaaaaa tacgggagag     3300

gcaccaaacc cctaaattct agtgcaataa tttaaaaaac aaaaaacaaa acaaaacaaa     3360

aaacatgtta tatgcacccc cctcccaaag ctgattttaa gactggctag aattcaaaat     3420

ataaaaaata aaactatgaa gtgatttgaa atcggtttta aaaagttgtt agtgcaagag     3480

aaattttatg tttaagccat catggcaata tatgcaaagt ttaaatgaat gacagaaatc     3540

ttgattttag actgtatgtt gtgctgtttt gagtacactt tatttcggag atatttagta     3600

ttttctatac actctgaaat catgagcatt tcactttttc taagtcaatt atttcataag     3660

gattttatta atagatattg gtaaatagaa ctttggaaat cttaattcag aattcttact     3720

atacctgagt cttttgtaag ctatagtttt atgtacaacc ttgtacagtt tttttgacat     3780

acaattcaga actttgttta ttctcttgga ctttgttctg gccaatacat tttttttaaa     3840

tctttaagaa gaactgtgat tgttttagtg ggtatttttc taattaaatg aaaacttgta     3900

taatggtatt ttagagaatg ccagtaagtg catgtttcaa gttaatgttt ttctcatcac     3960

ttgtatgttt ctaacacagc atgggacttt aataaaacca tcctggaaac ttaa           4014


<210>  1707
<211>  8450
<212>  DNA
<213>  homo sapiens

<400>  1707
gctcagaaac tgccagccca gaccacaggc tcagaggctg aagcaggagg aaggaaggac       60

tggaaggaaa aagagacagg ttagagggaa agaggcttgg gaagaaaaca gcagaaaaga      120

aactgctcat tacacttaca gagaggcaag taacggtgga gatgaggaca gagggaacca      180

agactctgaa agacaaaaaa tacaaataga gcgaaagagg aaaaaaatgt caagaagaac      240

atccatccgg agaaatgaag agaatgaaag ttttaagctg cagagccgtt ctgtgctttt      300

ccggcacaaa attatatcgc tgattttaag cccttttgca tttgccagcc gttgacatta      360

agaggcatgt ttaacggtgc caacagcatc tccttttcct tctcctcttc ctcttcttct      420

tcttcctcct cctcctcctc tttttcctcc tcctcgttct cctcccatca gcaagaagac      480

aaaccgagga cagtcttgaa atatcgaaat ttcctctttg ggatttgcca gcgccaagac      540

tgtcggaata aaggacgctg actattgtat tattgttatt ttattaatta gtcagtggaa      600

agattacaga tgaggaaagg ggacgcctgt cacccttcct gtgctaagat ttaaaaaaaa      660

atgaggctgg attgcgggaa gctctaaaat gaagcaaaag gagtaagatt tttaaagaca      720

gaaagccaca ggagccccca cgtagcgcac ttttatttgt attttttcag attttttttt      780

gtttcgtggt ggtgggggag gtgattgggt ggctgactgg ctgcgggaag ctacttcctt      840

tccttttgga gatgattgtg ctattattgt ttgccttgct ctggatggtg gaaggagtct      900

tttcccagct tcactacacg gtacaggagg agcaggaaca tggcactttc gtggggaata      960

tcgctgaaga tctgggtctg gacattacaa aactttcggc tcgcgggttt cagacggtgc     1020

ccaactcaag gaccccttac ttagacctca acctggagac aggggtgctg tacgtgaacg     1080

agaaaataga ccgcgaacaa atctgcaaac agagcccctc ctgtgtcctg cacctggagg     1140

tctttctgga gaaccccctg gagctgttcc aggtggagat cgaggtgctg gacattaatg     1200

acaacccccc ctctttcccg gagccagacc tgacggtgga aatctctgag agcgccacgc     1260

caggcactcg cttccccttg gagagcgcat tcgacccaga cgtgggcacc aactccttgc     1320

gcgactacga gatcaccccc aacagctact tctccctgga cgtgcagacc cagggggatg     1380

gcaaccgatt cgctgagctg gtgctggaga agccactgga ccgagagcag caagcggtgc     1440

accgctacgt gctgaccgcg gtggacggag gaggtggggg aggagtagga gaaggagggg     1500

gaggtggcgg gggagcaggc ctgccccccc agcagcagcg caccggcacg gccctactca     1560

ccatccgagt gctggactcc aatgacaatg tgcccgcttt cgaccaaccc gtctacactg     1620

tgtccctacc agagaactct cccccaggca ctctcgtgat ccagctcaac gccaccgacc     1680

cggacgaggg ccagaacggt gaggtcgtgt actccttcag cagccacatt tcgccccggg     1740

cgcgggagct tttcggactc tcgccgcgca ctggcagact ggaggtaagc ggcgagttgg     1800

actatgaaga gagcccagtg taccaagtgt acgtgcaagc caaggacctg ggccccaacg     1860

ccgtgcctgc gcactgcaag gtgctagtgc gagtactgga tgctaatgac aacgcgccag     1920

agatcagctt cagcaccgtg aaggaagcgg tgagtgaggg cgcggcgccc ggcactgtgg     1980

tggccctttt cagcgtgact gaccgcgact cagaggagaa tgggcaggtg cagtgcgagc     2040

tactgggaga cgtgcctttc cgcctcaagt cttcctttaa gaattactac accatcgtta     2100

ccgaagcccc cctggaccga gaggcggggg actcctacac cctgactgta gtggctcggg     2160

accggggcga gcctgcgctc tccaccagta agtcgatcca ggtacaagtg tcggatgtga     2220

acgacaacgc gccgcgtttc agccagccgg tctacgacgt gtatgtgact gaaaacaacg     2280

tgcctggcgc ctacatctac gcggtgagcg ccaccgaccg ggatgagggc gccaacgccc     2340

agcttgccta ctctatcctc gagtgccaga tccagggcat gagcgtcttc acctacgttt     2400

ctatcaactc tgagaacggc tacttgtacg ccctgcgctc cttcgactat gagcagctga     2460

aggacttcag ttttcaggtg gaagcccggg acgctggcag cccccaggcg ctggctggta     2520

acgccactgt caacatcctc atagtggatc aaaatgacaa cgcccctgcc atcgtggcgc     2580

ctctaccagg gcgcaacggg actccagcgc gtgaggtgct gccccgctcg gcggagccgg     2640

gttacctgct cacccgcgtg gccgccgtgg acgcggacga cggcgagaac gcccggctca     2700

cttacagcat cgtgcgtggc aacgaaatga acctctttcg catggactgg cgcaccgggg     2760

agctgcgcac agcacgccga gtcccggcca agcgcgaccc ccagcggcct tatgagctgg     2820

tgatcgaggt gcgcgaccat gggcagccgc ccctttcctc caccgccacc ctggtggttc     2880

agctggtgga tggcgccgtg gagccccagg gcgggggcgg gagcggaggc ggagggtcag     2940

gagagcacca gcgccccagt cgctctggcg gcggggaaac ctcgctagac ctcaccctca     3000

tcctcatcat cgcgttgggc tcggtgtcct tcatcttcct gctggccatg atcgtgctgg     3060

ccgtgcgttg ccaaaaagag aagaagctca acatctatac ttgtctggcc agcgattgct     3120

gcctctgctg ctgctgctgc ggtggcggag gttcgacctg ctgtggccgc caagcccggg     3180

cgcgcaagaa gaaactcagc aagtcagaca tcatgctggt gcagagctcc aatgtaccca     3240

gtaacccggc ccaggtgccg atagaggagt ccgggggctt tggctcccac caccacaacc     3300

agaattactg ctatcaggta tgcctgaccc ctgagtccgc caagaccgac ctgatgtttc     3360

ttaagccctg cagcccttcg cggagtacgg acactgagca caacccctgc ggggccatcg     3420

tcaccggtta caccgaccag cagcctgata tcatctccaa cggaagcatt ttgtccaacg     3480

agactaaaca ccagcgagca gagctcagct atctagttga cagacctcgc cgagttaaca     3540

gttctgcatt ccaggaagcc gacatagtaa gctctaagga cagtggtcat ggagacagtg     3600

aacagggaga tagtgatcat gatgccacca accgtgccca gtcagctggt atggatctct     3660

tctccaattg cactgaggaa tgtaaagctc tgggccactc agatcggtgc tggatgcctt     3720

cttttgtccc ttctgatgga cgccaggctg ctgattatcg cagcaatctg catgttcctg     3780

gcatggactc tgttccagac actgaggtgt ttgaaactcc agaagcccag cctggggcag     3840

agcggtcctt ttccaccttt ggcaaagaga aggcccttca cagcactctg gagaggaagg     3900

agctggatgg actgctgact aatacgcgag cgccttacaa accaccatat ttgacacgga     3960

aaaggatatg ctagtcaatt ctacaggact tacctgaagc agcatgattt gcacaaagtc     4020

gaccaacaaa agcatcaact tttcaacttc attatcttgg ccatccagtt agtcatgtgt     4080

aactgagtat tagatttcgg atggagtcat catggccaat tataggacct aattgctctc     4140

agcaggcctg agaaatgagt tgaaatgtgc agaactgtag aaactttaga ggcaacagat     4200

tttgcctccc cgatcagtgt gtgcctgttt acagcactat ctatctttct ctctccaaat     4260

gtcactgagc cctttagatg tttatattca ccacgagaag ccagtcataa agataaagga     4320

aatttgtgca ttataaatgc aatatcactg ttttaaactt gactgtttta tattattttt     4380

gtgtgatcaa gtgttccgca agctattcca actttacaag agaaattgtg attatgttct     4440

tttcacctgt gggttataaa aaatgttgta ttctgaagac ccacaaaata tcaaagacat     4500

tctgtagttt atacaccgtg ttgcaaagtg tttactgtac tatttcaaag cttctaaata     4560

aatataaaat atatatatta tattatataa ttttcctaaa atgtggtaca actcagttgg     4620

tttttaaatg gatgcataca gtccacatca tacaataaaa taaaaggtaa ttcagggtcc     4680

caaagacaaa cttactaaga aaaaatcatt aatagttttc tcccaatttc catatcttac     4740

tcaaccgtgt ttttccttgt ttaaaagaaa atgatgctct aagctacaaa attttgtcaa     4800

aaactcatat tgaattttca atgccaaaga tgtagctatt gatgttatca gacagagcac     4860

tgactatgta ctatcaaact atctaacaat ctgcataagt ctgattctat ttctatgact     4920

ttgaatttag aatcacttaa agcttttata aagaatcgat aaattcacct gtatttgttg     4980

ttagaaaaaa actgggtgtc tgtacatttt gtggtgtaaa atatgtaatt gaagattact     5040

attttaagaa gtcatcagtc atatcactca cacagaattt tattttacat agttttgtga     5100

cttaattaca catgaatata aaatctataa ttctatatga atatatagag atatagaaac     5160

atctgaactg gtaaagaata actataaaat atgaaagctc taaatttaaa ataaatttag     5220

agatagaatc atggtacatt attgtttcag tattccatgt gaaaatttta tagcttaaat     5280

gtagtcagtg tttgattaat gaaaaaattc ttcatgagtc agccttcaaa agttaagctt     5340

gccttttact tttatgtcaa caatattaat tattaaattt agtaagacgc actttccttt     5400

cttttatata ttttttctac tgttgtgtat gccttgttag aacacattcg agagaggaaa     5460

aaaatcagag aatataagat aatctttcaa gcaaaaaaca gaattgtcac agctcccctc     5520

gccctctaaa ctatgatatc aaaacatcat atcaaagctt caacattata tcaaaatgtt     5580

tgcccagttc aaattagaaa cctgttttga aatactttcc ttaattttta actgatctta     5640

tattcaatga cagtttgagc tgcactgtgt tattaaagaa tagactaaaa cttaacattt     5700

gacaaatgtt cttcatcaaa ttttatgtaa cttaagtgga aatttttccc tagatttaac     5760

tttaaaatac atatatatac acacacacac acacacacac acacacacac ttaggtcctg     5820

atatgtacat ttagagtgat atattggtat cactcatttg actgttatca aattagatat     5880

taatatatca tattccaatc agttcatata tcaaaataat gtatgtaatg ttccagcctt     5940

ttgaagtctc tttaaacata tatgaagcta acagatcata tgtaatacaa aaagcacata     6000

aattcactaa gtgcagcagt aacattttct taaactttgg cattactaca ttaatatttt     6060

gaatgataga ctattttagt aaggaaatgt ttatacataa tttaactgga aaaaagtctg     6120

tttgttccaa ctcttttttt tagcaagaaa atgattttct tgttgagtca ctctgcttta     6180

attaaaatgt ttcacgcatc attttgcaat catgggtgaa tatccacatc catcttcctt     6240

actgcatgca ttgaaaataa gattatactc acttcatgta tagtaattat attgtcattt     6300

acctcaaaga cattttcttt aattatttaa ccttttatat cattgtatat aatctccttt     6360

gaaccaactt ttttattata tatttgtgta ttagttattt tcatatatcc taggaactag     6420

ttatactaac ttacatttta gttatcatca atctacaaaa ccaaaaccag aacttcttcc     6480

taatttgcgg gacaaataga attgtttaag gataaaatgc tacattatta ggtcattaat     6540

caacttatct gttgcatcca aagtaaatta gaagttacaa cagagtaagg atatgattct     6600

tgtaagttgg ttaaaatgtt ttcttccaat gagggggact ataaaatgga aagtgcaacc     6660

aacaaataat gaaggtttct aattaagcat ttactagatt aatatatcaa ggaattttag     6720

gataggtttt ctctttaatc tggtcattct aatatccaat cttacataat tttatataca     6780

tcaaagaata atatccatcg tattagacag tatttcgtca ataaattatt tcagaaaaaa     6840

aaatcatgtc atttactcct tgttaacatg gttagtttta gagcagtcaa agtcaaaaaa     6900

aatttcctgt ggaaacagtg tcttaatgtt tcaaaggtat gtcaaaagac aatttttaga     6960

aaatatttca tccacatgta gaattctaat ttttaacgtg tgaacatagt ttggtgaaat     7020

catcttaaat caaatttaaa tatcacatca gaattacttc acagatataa tagcgtcaat     7080

gatatatgta tcatcttttc ttggcaaata ttaaggaaat atgtgtattt tattttttaa     7140

agatattaaa tgcactgcct ttatcaaaca ttgcaaatta agaactatag tagaatattt     7200

aaatatttta atttctcatt gttttatttg ttaattggat tgtaatttgc catcagattc     7260

tctgtattat agaagctatc ttgcttcttc aataagagga ggaaaaagaa tctcacaatt     7320

cccaatataa tctttaacaa ctgtacgtta attgtaccat tttaccttct aaacattatt     7380

tactggagct cagttagtct ttaaaacaat tactcaggca gagtgtggca aaagttcagc     7440

aagatcaaga aaagtattta agttattgac tgatcatagc actgttattt gtcattgcat     7500

gtgtttttcc ccctcatgtt tctatgtgtg ctattgatac ccaaggaact caaaaatact     7560

taaaatattg gtatacttga tgatttttct gaaaatctta tatttttcat attacaaatt     7620

cttgagttct ttatcttttt caagtctaat tttgtagtgg taaaggcttt gcacttaaca     7680

tccttttgtg ttccttttta acaaggaaaa acagaaaata atggaattcc atatttttta     7740

caccatggag tagtaaaatt attttatata ttgttagtac ttcaacaaac atccctctgc     7800

taagtcagac aaaatcctta tacagtaatt tgtgaaactg ttcagtagag tattcttttc     7860

ttcaaatctt ggcataggtt ttagattata gcattctgta tgaatgcagg tagatgggtg     7920

ccgccagagt attgcaggca ataatacgac taaaattcta atacttttag tgtgcatgcg     7980

tgtatttcta atcactgtta ttttttaagt atttgtaaaa ttagaaaaat tgcttttatt     8040

tcttgaaaag ttgtcacatg cttagtttga agttttactc tccagatgtt tttgagttgc     8100

ataaaaatct tgcattcatc attcaaaaaa tactaaattt cacatgagac tcaaaaattt     8160

ctgaatgatg gaactcagac ttccaataca ttcatacatg ctagagctga aagtaagcag     8220

ggaatttcag ctctaaacac atttttgaga cagttatctg tgagtgaaaa cagggtatta     8280

taacaaaaga tgagtttcaa tcttaactac agtgtttgtt actgtgaatg ctataataat     8340

acataagtaa aatgagtgta aatgtaataa attattttat actgctgtat acatatgaaa     8400

taaataaaac taggatacat attaaaaaaa aaaaaaaaaa aaaaaaaaaa                8450


<210>  1708
<211>  3979
<212>  DNA
<213>  homo sapiens

<400>  1708
gaaagaaagc taggactggc tcaaaggttg gatctgaaag ttggggttga tgaatggccc       60

atgtcaaagt cttaggaaag cggaggggct tttggagggt tgcacttcgg ccgtcaccgt      120

cttcaggaaa ctccctttgg attccaaggc tcaaagtcag aaaatgagat acaagacatc      180

cttggtgatg aggaaacgat tacggcttta ccgaaacact cttaaagagt caagtagcag      240

ctctggacac catggccccc agctcaccgc cgcctccagc ccctcggtgt tcccgggcct      300

ccacgaggag cctccccagg cctcccccag ccgtcctttg aatggactcc tgcgtctggg      360

gctccctgga gacatgtacg cgcggccgga gcccttcccg ccagggcctg cggcccgcag      420

cgacgccctg gcagctgccg cagccctgca tggctacggg ggcatgaacc tgacggtgaa      480

cctcgctgcg ccccacggtc ctggcgcttt cttccgctac atgcgccagc ccatcaaaca      540

ggagctcatc tgcaagtggc tggcggccga cggcaccgcg accccgagcc tctgctccaa      600

aactttcagc accatgcacg agctggtcac gcacgtcacc gtggagcacg tcggcggccc      660

ggaacaggcc aaccacattt gcttctggga ggagtgtccg cgccagggaa agcccttcaa      720

agccaaatac aaacttgtaa atcacatccg cgtgcacacg ggcgagaagc ccttcccttg      780

tcctttcccg gggtgtggga aggtctttgc tagatcagaa aatctcaaaa tacacaaacg      840

aactcacaca ggcgagaagc ccttcagatg cgagttcgag ggctgcgagc ggcgcttcgc      900

caacagcagc gaccgtaaga agcattcgca cgtgcacact agcgacaagc catacacgtg      960

caaggtgcgg ggctgcgaca agtgctacac gcaccccagc tcgctgcgta agcacatgaa     1020

ggtgcacggg cgctcgccgc cgcccagctc tggctacgat tcggctacac cgtctgccct     1080

cgtgtcgccc tcgtcggact gcggccacaa gtcccaggtg gcctcctcgg cggcggtggc     1140

ggcgcgtacc gccgacttga gcgaatgatg tccaccgcgt tgctcgcaag gtaatctcgc     1200

tccgcgcagc tgagcgcccc gcatctcgcg cctgctacat caaagggccc gcgcacaaag     1260

cagtgtttct tcgccacggt gcatcttcat ggtaagttag gatttctatg gcaatgtgca     1320

agtcgcactg aaatcctgaa aggccaagcc tggagcccgt ccaggctttt cattaaggac     1380

ataatattta cgtctaacag accttttttc ttgtgtatac aagtatatat ttttgtttga     1440

cgcggactaa atcattttca tttaatttcc ggtaaacaaa acccacgcga atgggcactt     1500

gtacccgatc ataataaaaa tggataataa tgtgaaggaa gaaaagagcc gcttgaatcg     1560

ccgctcagcc ccctttgttt ctgctttctg cggtgatcag agggcgcgtt tgggtttgat     1620

ggcgagtttc taaaggcgag gaaatggttt gtaagagggg aaagaaaagg agaaaggtct     1680

aatcaagctc gggttgttca aagagtcggg ttttggggtt gaaagtgtga gtttgacggt     1740

gcatcagcat gccgcgttag gctcgccatg gaaatacgcg cggggagcgg ccgcttcaaa     1800

ggcggcacac ttcactacag acactctatt aagatacatt tgcgctgacc tttgctttca     1860

cgccatttaa tactgtcact gcgctctcca gtatatactt cctttctaga acccgacttg     1920

cccacgttta ggggttcact ctgcaccctg atgtgggagg ctttggcgca ggggacactt     1980

tcaggaaagg gaggagcaca aggactctgt gcatcttgac tgcaccccaa agaggctcca     2040

ggatcaggag tgaaagattt taaagcagcc tccgaagctt aacaaatgag cattccaagc     2100

tcagttttgt gcaaatcgcc tttctgactc ttgagtagga tggaggctta aatttaatgg     2160

cgacttgggg ggaagggagc caccctgggg gagtctgagg agttcagact gtgcccttgg     2220

gaatttccac tctggctttc cgtgccactc ttcttccttt ccatcccaaa agtctcttgc     2280

ggcccctgaa acttgtttct ttctaaggca gggtgtgtgg tacccttagg cctggactag     2340

tcctagatgc aaactcaaga gcccaaggcc aaggggatgt ggggaagatg gcaggaaagt     2400

tagaagtcca tgttccctta attgtcttgt tgtttatttt atccaagtac cccagtgaat     2460

aggggaaaaa taaacacagt gaaaaaaaaa atcaaacagt ggagtcttct ttagtgccag     2520

tccttgtggt tgaataaaaa ggatggtccg ctttctattg agctgagaaa tctttgaagt     2580

gggagttatt atctgagaca ttcctgcttg tcgtcctaac aacgctgatg aaacgtaaaa     2640

ggttctttgt cagcgatttg ttctcctctc tgtcaaactc cctctgcccc gttagtttca     2700

aaccgtttct aaagagataa aaatcaaact tcttttaaaa caatatccac acactgcatc     2760

aatacataac tttaggtcta agtcttgcta agggataaac aaaagcaatg cctagacatc     2820

agggtcaggg cctggtctgg tgaagtatgc agaagttggg gggccctcgg gacaagcttt     2880

gggacatgag gaaaagaatg cagagagggt gcaagcagaa tacataccct aagtccataa     2940

ttgtgtttct gcttctttct gctctggttt gcattcaatc agcccaagtt gggtcacata     3000

gatgggtttc ctttgggtac ccctcaggct cctaatattc ttgcccagga tccttggaac     3060

ttaagaatgc agccaagcaa ttgttaatat ctcctgctcc ttcaaagcca cctctgctaa     3120

aaatagaccc attgtgtgtt tcttctcact agcagcaatc aacaagccct ttctgccgtt     3180

aataagaagg agaatagctg aaggagagag atattttatt aatttcctgt ttccttcaga     3240

atcttggcaa ttgaagttta gaaggtttgg tctacaacac agtgatcgaa aatgcatgta     3300

aatgcccatc cttcccttca ttcacgtgtg aagttgttca ttttatattg tgcccagcaa     3360

agaaactttc acccagttca ggtttcccca aaactcctgt ggtggtttta aaggtggttt     3420

aaataaataa ggatgtgctg gtccccctac tctgtgtgtg ctgaataaat ggcttgtaaa     3480

gaagtttttc caagctgtaa cccatgctgt tattatagtt gctgcaaaat gttcttcctg     3540

atattgattt tatttgttaa ctgaaggtct ccatatgttt gtttatattg ctaatttatg     3600

agaaaatgta ataattgcaa tgaatgtgaa ttatacagac aggcaaacat tttgtaatca     3660

taattcacat atacacaaaa gcctggctga aatctttaga ctatttgtac cctctctacc     3720

cacactgttt gtgatttatc atctgtctct ttagtgtcag ttaaattatg aactaacttg     3780

aaaataaaag ttgtttgact gaaagtgatt gttgaatgaa caacaaagtt gaaagccatg     3840

gcttgatctt gtaaatatat aaatgtaaat gatattaaat ctgtgattcc ttttccctcc     3900

aaaggctttt gtgtacatgg cgctgcattt ggctattttc tttggaaata aataatgtga     3960

tgtttctctt cctcttttg                                                  3979


<210>  1709
<211>  2692
<212>  DNA
<213>  homo sapiens

<400>  1709
gtcacggagc gcttaagagg agggtcgggc tcggccgggg agtcccagtg gcggaggcta       60

cgaaacttgg gggagtgcac agaagaactt cgggagcgca cgcgggacca gggaccaggc      120

tgagactcgg ggcgccagtc cgggcagggg cagcgggagc cggccgggta gggtgcagcc      180

tgaggcttgt tcagcagaac aggtgcaagc cacattgttg ccaagacctg cctgaagccg      240

gattctcccc actgcctcct tcaaccccgc ctcttcctcc tcctgtggga ctgctccccc      300

ctcctgtgag gctagataga tgccctgtat ccaagcccaa tatgggacac cagcaccgag      360

tccgggaccc cgtgaccacc tggcaagcga ccccctgacc cctgagttca tcaagcccac      420

catggacctg gccagccccg aggcagcccc cgctgccccc actgccctgc ccagcttcag      480

caccttcatg gacggctaca caggagagtt tgacaccttc ctctaccagc tgccaggaac      540

agtccagcca tgctcctcag cctcctcctc ggcctcctcc acatcctcgt cctcagccac      600

ctcccctgcc tctgcctcct tcaagttcga ggacttccag gtgtacggct gctaccccgg      660

ccccctgagc ggcccagtgg atgaggccct gtcctccagt ggctctgact actatggcag      720

cccctgctcg gccccgtcgc cctccacgcc cagcttccag ccgccccagc tctctccctg      780

ggatggctcc ttcggccact tctcgcccag ccagacttac gaaggcctgc gggcatggac      840

agagcagctg cccaaagcct ctgggccccc acagcctcca gccttctttt ccttcagtcc      900

tcccaccggc cccagcccca gcctggccca gagccccctg aagttgttcc cctcacaggc      960

cacccaccag ctgggggagg gagagagcta ttccatgcct acggccttcc caggtttggc     1020

acccacttct ccacaccttg agggctcggg gatactggat acacccgtga cctcaaccaa     1080

ggcccggagc ggggccccag gtggaagtga aggccgctgt gctgtgtgtg gggacaacgc     1140

ttcatgccag cattatggtg tccgcacatg tgagggctgc aagggcttct tcaagcgcac     1200

agtgcagaaa aacgccaagt acatctgcct ggctaacaag gactgccctg tggacaagag     1260

gcggcgaaac cgctgccagt tctgccgctt ccagaagtgc ctggcggtgg gcatggtgaa     1320

ggaagttgtc cgaacagaca gcctgaaggg gcggcggggc cggctacctt caaaacccaa     1380

gcagccccca gatgcctccc ctgccaatct cctcacttcc ctggtccgtg cacacctgga     1440

ctcagggccc agcactgcca aactggacta ctccaagttc caggagctgg tgctgcccca     1500

ctttgggaag gaagatgctg gggatgtaca gcagttctac gacctgctct ccggttctct     1560

ggaggtcatc cgcaagtggg cggagaagat ccctggcttt gctgagctgt caccggctga     1620

ccaggacctg ttgctggagt cggccttcct ggagctcttc atcctccgcc tggcgtacag     1680

gtctaagcca ggcgagggca agctcatctt ctgctcaggc ctggtgctac accggctgca     1740

gtgtgcccgt ggcttcgggg actggattga cagtatcctg gccttctcaa ggtccctgca     1800

cagcttgctt gtcgatgtcc ctgccttcgc ctgcctctct gcccttgtcc tcatcaccga     1860

ccggcatggg ctgcaggagc cgcggcgggt ggaggagctg cagaaccgca tcgccagctg     1920

cctgaaggag cacgtggcag ctgtggcggg cgagccccag ccagccagct gcctgtcacg     1980

tctgttgggc aaactgcccg agctgcggac cctgtgcacc cagggcctgc agcgcatctt     2040

ctacctcaag ctggaggact tggtgccccc tccacccatc attgacaaga tcttcatgga     2100

cacgctgccc ttctgacccc tgcctgggaa cacgtgtgca catgcgcact ctcatatgcc     2160

accccatgtg cctttagtcc acggaccccc agagcacccc caagcctggg cttgagctgc     2220

agaatgactc caccttctca cctgctccag gaggtttgca gggagctcaa gcccttgggg     2280

agggggatgc cttcatgggg gtgaccccac gatttgtctt atccccccca gcctggcccc     2340

ggcctttatg ttttttgtaa gataaaccgt ttttaacaca tagcgccgtg ctgtaaataa     2400

gcccagtgct gctgtaaata caggaagaaa gagcttgagg tgggagcggg gctgggagga     2460

agggatgggc cccgccttcc tgggcagcct ttccagcctc ctgctggctc tctcttccta     2520

ccctccttcc acatgtacat aaactgtcac tctaggaaga agacaaatga cagattctga     2580

catttatatt tgtgtatttt cctggattta tagtatgtga cttttctgat taatatattt     2640

aatatattga ataaaaaata gacatgtagt tggaactgaa aaaaaaaaaa aa             2692


<210>  1710
<211>  4664
<212>  DNA
<213>  homo sapiens

<400>  1710
gcagcctccc ggcgctgagc gcttttcctg cccgcccggc tcagccctgc ggaccccggg       60

agaagtttcc cagaaaaaat gcccagcgcg gcgcggggct gcggagtcgt ccggagccgc      120

tgcgcgattt atcagcaaga ctgttgaacg cataactgcc caagatgcct gtccctcccc      180

ctccagcacc cccgccgccc ccgacgtttg cactggccaa tacagagaag cctaccttga      240

ataagacaga gcaggctggg agaaatgctc tcctttctga tatcagcaaa gggaagaaac      300

taaagaagac ggtcaccaat gacagaagtg caccaatact ggacaaacct aaaggagctg      360

gtgctggagg cggtggtggt ggctttggtg gaggcggcgg atttggcgga ggaggtggtg      420

gcggaggcgg tggaagtttt ggagggggcg gacctccagg tctgggagga ttgttccagg      480

ctggaatgcc gaagctgaga tccacggcca acagggataa tgattctgga ggaagccgac      540

caccattgtt gccaccggga ggaagatcca catctgcgaa acccttttca cccccaagtg      600

gcccagggag gtttcctgtg ccttctccag gccacagaag tggtccccca gagcctcaga      660

ggaaccgaat gccgccccca aggcccgacg tgggctcaaa gcctgatagc attcctcctc      720

cagtacctag tactccaaga cccattcaat caagtccgca caaccggggg tccccaccag      780

tgcccggagg ccccaggcag cccagccccg ggcccactcc tccccctttc cctggaaacc      840

gcggcactgc tttgggagga ggctcaatac gtcagtcccc cttgagctcc tcctcgccct      900

tctccaaccg gcctcccctg ccgcctaccc ccagcagggc cttggatgac aaaccccctc      960

caccacctcc tccagtgggc aacaggccct ccatccacag ggaagcggtt ccccctcctc     1020

ctcctcagaa caacaagcct ccagtgcctt ccactccgcg gccttcggcc tcctcacagg     1080

ccccacctcc gccgccacct cccagcaggc ccgggccgcc tcctctgcct ccaagttcca     1140

gcggcaatga cgaaacccca agactcccac agcggaatct gtccctcagt tcgtccacgc     1200

ccccgttacc ttcgccagga cgttcaggtc ctcttcctcc cccgcccagt gagagacccc     1260

cacctccagt gagggacccg ccaggccgat caggccccct cccaccacct cctccagtaa     1320

gcagaaacgg cagcacatct cgggccctgc ctgctacccc tcagttgcca tccaggagtg     1380

gagtagacag tcccaggagt ggacccaggc ctccccttcc tcctgatagg cccagtgctg     1440

gggcacctcc cccacctcca ccatcaacat ctattagaaa tggcttccaa gactctccat     1500

gtgaagatga gtgggaaagc agattctact tccatccgat ttccgatttg ccacctccag     1560

agccatatgt acaaacgacc aaaagttatc ccagcaaact ggcaagaaac gaaagccgga     1620

gtggatccaa ccgaagagaa aggggtgctc caccactccc tcccatcccg aggtgatctt     1680

tgcctgctct tctctaccca agctcaagag ctgcttctgt tgctatctaa gaactgcata     1740

ccctcctccc tgcttcttcc cttgtgcctc atgtatgggc aggaggaaag gtgggagggg     1800

gagtgggaat atgcgtgtgt gggtgggaat cggtaagaaa tgcacctagc ttttcatatt     1860

gtgtttattc tccaggctat tgcttgcttc agctgcagcc tgcctgtgct ggctgctggg     1920

gtcgataggc ttttgtcgta ataggcagag atgacttgca tcccagcttt ccaccaacca     1980

aattcaaaca ttcactgctt atttgttaca gactgtaatt attaaagtcc ctgagagctg     2040

ttttctcccg ttcctttttc gcatgcttgg cctcctctct gtttctatga accacagacc     2100

acctaagcaa gctgctgagt aagggctcac tggaaacttg cagtcacagg atgtccaatc     2160

tttggcagtc cgagcttggc tctaggacag agctgtccaa tagaaatata atgtgagccc     2220

catatacaat ttttacattt ctaatatatt ttaaacaagt gaagttaata tgcatccaaa     2280

atatttcaac ctgtaatcaa cataaaattt taatgagata ttttatatta ttttttggta     2340

ctgaatcttc aaaatccaga gtgtatttta cacttaccgc acatctccat tcagactagt     2400

cacattttta agtgctcagt agccacatgt ggctggtggc tactggatta gacagcacga     2460

gtctggaaga tggaagctag tgcagaaacc tcttgtttaa aaaacaaaaa aggcaagatg     2520

ggcttgagcg attcaagagg caactaaaaa taaaattagg acccagcacc ttgtttgaca     2580

cacagtttga ccttcgattt tcctccctta acttccctct tcccttaata tctgtataca     2640

agtgttgctt caaagtacca aggtcagaaa ttgattcagt acggtttact aaagtcatgt     2700

ggaataaagc cattggaaac aaatggaaag cctgtcggga cttctgggct cagaaccagc     2760

tggctcacgc actccacttg tcagctggac ttctgccttg tgaaatggaa gcagcctttg     2820

ttcctttctg gctgagcaag ctcctgaggc tgggagagac taggaaggct tggtaggagg     2880

ggaaaaaagt caggaaaaga tatcaaatca gaaacatgga agaagaaggg aaccgatttg     2940

agttggtggg caaaactcta aaaatctaaa tctgatgctt atgtaagggt tgagcgaatt     3000

agggagattg ctagtggaaa ttggagggaa tttgttttgc atcatttgtc taggatctat     3060

gcaaatatag ctccactaaa ggaccatagg gaagagccag ccttgccttt tcttatatga     3120

ttttgtttac aaaattttac tgggactttt aaatctagct atagagttgg gaaaaaatat     3180

ttccacttag atattttaca tggttttgtt taaaattacc attacttgtt ttttaaaaac     3240

acatgaccac atatgtatat gtatatctac ctaaacattg tatcatggtt tcagtatgtt     3300

attcatgtat tactgggaga tgctaccaag aaaccaaccc aaagaaaatt ctgaaaaata     3360

catttctatt tatagaataa atgtttcatt tatataaaag caaaagaact tagagttcta     3420

ataaatggga tgtctaataa attatgaagt tactgatttg aatatattat atttttataa     3480

cttccttgcc aaagtcctga tttagtacat tagagaacct gtgtttcctc tctcctctac     3540

cattcatctc tcttccatac agtcatttgg gctttttact caaagagaat caagaaataa     3600

taaggtataa caagcttggc aaagtgttgg ctttttaaaa aaaaattttt ttaatctcta     3660

gcagtttggt aatttagcag catcatttat ttgggattct tttatctgat ttcaacagtg     3720

aaaaacatcc ctatgataaa gcctaatgac ccatttcaca aaagatggaa tttgcccttc     3780

ctagaaaata tgacggagaa aagtctgact cagagaaagt gagtctgaat tttataaggg     3840

gtagtaagaa ttggacaatt cctttgcata tctgaacttg gcaggtaccg ttctaaatct     3900

gaaacagggt gatagctcaa agttgccatt catccagaat agattgtttt agaatgtagt     3960

gtttaagtga ctgtttcatt aatacaccta caccctttct ttgaaagttt gcaacctaat     4020

tgcatctaaa actatgaata agttctgtgg taaaatctta aactatggaa aattacaaaa     4080

atgaattttt cttccctgaa atcagagctt acatgtgtgt ttttttataa cattttcaga     4140

taaatgtatt caacatgtaa tacagtattt taacattcac ctcttatttt atattgaaat     4200

gtattacagt attaaaactc agtgttcagt atttatttca ctatgcattt tatttagtaa     4260

aagccaggag aaatgtttaa tccaatggtg ccttactttg tgatttaaaa gaaatcaact     4320

tttttttatg tctaagtagt agattatttg catatttgta aaaactgtta ggtctttata     4380

ttttaaagtg taataccagt tttgttattt tagtagcaga aatgggatga ttgttaaagt     4440

tccccaaaaa tgttggcatg aaattaattt ttccctcctt atagtcaagg accgtagagg     4500

aagaaaaact tttttttcat accatgcact atgtaaacag acacattttg ctatctgtgt     4560

catcaggata gtgtaagtgg tagggtagag actaccctag acatctgcat ctttgtaagt     4620

tagccagaca ataaagaaaa gcagaatgaa aaaaaaaaaa aaaa                      4664


<210>  1711
<211>  1505
<212>  DNA
<213>  homo sapiens

<400>  1711
cagagtctcc gcttaggcgg cccgtggggg tcggggtcgc ggtcgcggtc gcggaccggg       60

gacagagcaa tggggcgggc gcgcagcgcc ggctgcactc ccagagcctc ccaccgccgc      120

cccacggccg cctagcgcgc gccgggactg catttcccat aggcccacgc tgcggagcac      180

cgcccacccg agtctcacgc gagtgcgctg ccgcgaggtg tccctgccgc agcccccgcc      240

cgcccgcaga gcttttgaaa ggcggcggga ggcggcgagc gccatggcca gtccgggctg      300

cctgctgtgc gtgctgggcc tgctactctg cggggcggcg agcctcgagc tgtctagacc      360

ccacggcgac accgccaaga agcccatcat cggaatatta atgcaaaaat gccgtaataa      420

agtcatgaaa aactatggaa gatactatat tgctgcgtcc tatgtaaagt acttggagtc      480

tgcaggtgcg agagttgtac cagtaaggct ggatcttaca gagaaagact atgaaatact      540

tttcaaatct attaatggaa tccttttccc tggaggaagt gttgacctca gacgctcaga      600

ttatgctaaa gtggccaaaa tattttataa cttgtccata cagagttttg atgatggaga      660

ctattttcct gtgtggggca catgccttgg atttgaagag ctttcactgc tgattagtgg      720

agagtgctta ttaactgcca cagatactgt tgacgtggca atgccgctga acttcactgg      780

aggtcaattg cacagcagaa tgttccagaa ttttcctact gagttgttgc tgtcattagc      840

agtagaacct ctgactgcca atttccataa gtggagcctc tccgtgaaga attttacaat      900

gaatgaaaag ttaaagaagt ttttcaatgt cttaactaca aatacagatg gcaagattga      960

gtttatttca acaatggaag gatataagta tccagtatat ggtgtccagt ggcatccaga     1020

gaaagcacct tatgagtgga agaatttgga tggcatttcc catgcaccta atgctgtgaa     1080

aaccgcattt tatttagcag agttttttgt taatgaagct cggaaaaaca accatcattt     1140

taaatctgaa tctgaagagg agaaagcatt gatttatcag ttcagtccaa tttatactgg     1200

aaatatttct tcatttcagc aatgttacat atttgattga aagtcttcaa tttgttaaca     1260

gagcaaattt gaataattcc atgattaaac tgttagaata acttgctact catggcaaga     1320

ttaggaagtc acagattctt ttctataatg tgcctggctc tgattcttca ttctgtatgt     1380

gactatttat ataacattag ataattaaat agtgagacat aaatagagtg tttttcatgg     1440

aaaagccttc ttatatctga agattgaaaa aaataaattt actgaaatac aaaaaaaaaa     1500

aaaaa                                                                 1505


<210>  1712
<211>  7498
<212>  DNA
<213>  homo sapiens

<400>  1712
agaggagccg ggacaccgag ggaagaggcc ggagggagat cgcggagggg agggggcggg       60

aggggggtgg ggtatcctga gtcgtccgtg gtccggagtc tggaaggccc tagagcggcg      120

ccagtcgacc cgcctcgcca caacttgccc agaccagaca cgtttcatcc tgcgccctgc      180

aagaaggagc cggcctgcct ctctccgctt tgctgctcct cggcctccgc gggcccggcc      240

cgcgtcagca gcgaccctgg ggtctgggtc ccctgtgtcg cccccgcccg cctgcagcgc      300

ccggcacccg cccaggagcg cgcagctggg gttctaggga cgtatacttg agcaagagag      360

accacagctc ttgttcccgc tgatcctgca gcccagtgga tggagtccag aatctacaga      420

cctgccagga aagaaaaaaa aattcctgat gtctggtcca agcaggaatt ccccggtgga      480

ttggggaatg tctggctttt cctcagctta ttgatctctg tggtaaccac tggaggcccc      540

cagaagaccc atagaaatga gaggcctgag gtctacaagt cgctgctaga aatattttag      600

cctctccaaa gcccagaatg cagccccgac ccaagtttgt aagggttctg ggtgcacgct      660

gaccctgcgc gggcagacgc gccctttgct ccaggtccgg acctgggcgc tgctatagca      720

acgtcctgga cgcccagacc ttaggccgcc gccgccgcgg aagcgaggaa cccggccttc      780

tcccgctcct gagggctgtg gcggcggcgg cccgggaggc ggcccaggct gggtaaagac      840

cgcccggctc ctcctatgca agctgaggca gcggattggt tttcaagcat gcccttccag      900

aagcatgtct actacccgct cgccagcggc ccagaggggc ccgacgtcgc tgtggccgcc      960

gccgccgcgg gtgcggcctc catggcctgt gcgcccccca gcgcggcttc ggggcccctg     1020

cccttcttcc agttcaggcc gcggctggag agtgtggact ggcggcggct gagcgccatc     1080

gacgtggaca aggtggcggg ggctgtggac gtgctgacgc tgcaggagaa catcatgaac     1140

atcaccttct gcaagctgga agacgagaag tgcccacact gccagtcggg ggtggacccg     1200

gtgctgctga agctcatccg tctggcgcag ttcaccatcg agtacttgct gcactcacaa     1260

gagttcctca cctcgcagct gcacaccctg gaggagcggc tgcgcctgag ccactgcgac     1320

ggcgagcaga gcaagaagct gctcaccaag caggcggggg agatcaagac gctcaaggaa     1380

gagtgcaaac gccggaagaa gatgatctcc acccagcagc tgatgatcga ggccaaagcc     1440

aactattacc agtgccattt ttgtgacaag gcctttatga accaagcttt tctacaaagt     1500

cacattcaac gccgccacac tgaagaaaat tctcattttg agtatcagaa aaatgcacag     1560

attgagaagc tccggagtga gatcgtcgta ttgaaggaag agctgcagct caccaggtct     1620

gagctagagg ctgcacacca tgccagtgca gtcagattct ccaaggaata tgaaatgcag     1680

aaaacaaaag aggaagactt tttgaagtta tttgacaggt ggaaagaaga agaaaaggag     1740

aaactagttg atgaaatgga aaaagtcaag gagatgttta tgaaggaatt taaagaatta     1800

acttcgaaga attcagcatt agaatatcaa ctgtcagaaa tccagaagtc caatatgcag     1860

atcaagtcca acataggcac attaaaagat gcacacgagt ttaaagaaga ccgttctcca     1920

tatccccagg atttccataa tgtcatgcag cttcttgata gtcaggaaag caaatggaca     1980

gctcgagttc aagctattca tcaagaacac aagaaagaga agggtcggct cctgtcacat     2040

atagagaaac ttcgaacctc aatgatagat gatctaaatg caagcaatgt tttctataag     2100

aaaaggatag aagagctagg gcagagactc caggagcaga atgagctgat tataactcag     2160

agacagcaga ttaaagactt tacctgtaat ccattaaaca gtatcagtga acccaaagga     2220

aatcctttag cctggcaggc ttttgaatct cagccagctg ctccagctgt gcctatgaat     2280

gccccagccc tgcacacttt ggaaactaaa tcaagtctgc caatggtgca tgaacaggca     2340

ttctcgtcgc acatactgga accaatagaa gaactttcag aggaagaaaa aggaagggaa     2400

aatgaacaga aattaaataa caacaaaatg catttaagga aagctttgaa gagtaactcc     2460

tccctcacta agggactaag aacaatggtg gagcagaact tgatggagaa actggaaacc     2520

ttggggatta atgcagatat acgtggcatt tcaagtgatc agttgcatag agtactaaaa     2580

agtgtggaat cagaaagaca taagcaagaa agagaaatac ctaactttca tcaaattcga     2640

gaattccttg aacatcaagt cagctgtaaa attgaggaga aagcactact ctcttcagat     2700

cagtgcagtg tttctcaaat ggataccctt tcaactggag aagtacccaa aatgatacaa     2760

cttccttcca aaaacagaca actgattaga caaaaagctg tttctactga taggacatct     2820

gttccaaaaa ttaagaaaaa tgtcatggaa gatccttttc ccagaaagtc ttcaactatt     2880

acgacccctc cttttagttc agaggaggag caggaggacg acgacctcat ccgggcatac     2940

gcatccccag gcccacttcc tgtgccgcca ccacaaaaca agggcagctt cgggaagaac     3000

acagtgaaaa gtgacgcgga cgggaccgag ggaagcgaaa tcgaggacac tgatgattct     3060

cccaagcccg caggagtcgc cgttaaaaca cctactgaaa aagttgaaaa gatgtttcca     3120

catcgcaaaa atgtgaacaa accagtcggt ggaactaatg tccctgagat gtttatcaaa     3180

aaagaagaat tacaagaact aaagtgtgcg gatgtggagg atgaagactg ggacatatca     3240

tccctagagg aagagatatc tttgggaaaa aaatctggga aagaacagaa ggaacctcca     3300

cctgcgaaaa atgaaccaca ttttgctcat gtgctaaatg cctggggcgc atttaatcct     3360

aaggggccaa agggagaagg acttcaagaa aatgaatcaa gcacattaaa aagcagctta     3420

gtaactgtga ctgattggag cgacacttca gatgtctaat tccacatgtc agaagattat     3480

tccagaagcc agcagtattt cagtatcaca gtgtttcagt aatttgcctc catgattcta     3540

gtgcttctgc cttaccgtgt ttcccacagc aacacagaga ctgattcaaa gaacaatggt     3600

ctctttaatg gcacccaata cagtattgaa aatcagatca tcaacagtat ttcgaagcat     3660

gtaaaggtgt ttaagacttc cgctgctgct taaaaataac atgtcattga agtcataaaa     3720

agttttttct tcagaaaggt actctagtgt taagtgtatt tttttcaact aattttttag     3780

tgaatttttt ttaaacttac agcatgtttt ggtttgaatt actaaaactt taaaaaatat     3840

ttttcttatg tatgctgtcg tatcgtaggc gtttatatta taaaattctg ttagtagtct     3900

taaaattgaa ttggtggaac cactaatcct taaaagttag tctggttatt tttcatatag     3960

aagtaagttt aatccgagtg tggtggtgtt cacctttaat cccagctact tgggaggctg     4020

aggtgggagg ataacttgag cacaggagtt caagaccagc gtgggcaata tagcaagact     4080

ccacccctcc acaccccaaa aaagtaagtt taggattaga atatagctag gtccaatgtt     4140

aaatacattt tcctggagta catttgtcac attcagcttt gagccactgt aagcatgtta     4200

ctattaaatg gttggttatt ttatatagca tattctttat cttggatatt ttatgaataa     4260

agtatagtta ttttaagtgc caattaattt atcagactaa atagaaaata tttgagccat     4320

tactgaattc acatatgtat gttttttttt actatttaaa atacccaaca tgtattatga     4380

aatacctcaa aagtaattta gttacattct taaacaatga cattgtcgaa agaaagttct     4440

tataagctgt tttttgcatt tttataactt ggttatacta tattctgttt ccaagtaacc     4500

ttttaactaa aagatttgtt gggttttaga tctcttttca tttgtcaacc ttttcagtaa     4560

agccctctgt tacatcactg tgactgtggc tgtgttatta gagatgaatt ctgagttaaa     4620

tttgtactta ttaggggtct tacagaggga gaatctggcc ttgattgcta tgccatatga     4680

cattctgtcc taatggttag aacaaatctt tatctgtttc cacccaccct gggatccttt     4740

ttacttgtag cccattcctg ccctctaaaa gaatccttcc aacttcctat aggggccatt     4800

tcatgcagat atactcactt tatatgtatg tttctaaaag ctttagtgaa ggctgaatcc     4860

aagtttcatg tagtaggaca gagaacagaa ggccgaatcc aagtttcatg tggtaggaca     4920

gagaacggca atctacaaaa ctacaccaag cctaagatgg cccatgtgcc actttgttca     4980

ttcatttatt tattcagcag atatttattg aaccacttgg tctggtttgg ttttgaacac     5040

gcactaattc atttaattac aacaactttg cgatgtagtt attgttataa tcctcatcct     5100

aaaggtgtga gaaacagagt tattaagtaa gttgccagaa gccatacaag tacaaagtgt     5160

caaggggaga ctttaagcca ggtctctatt ccatgttttg tgtctgccat gttttcattc     5220

ctgagcagaa gagcttgggg aaatgaactt ttgctaagta aacccagtat ttaaattaag     5280

tcactatatc tgtgtctttt aagagcccct cctttagctt acatggttag ttgtatcttt     5340

tttttttttt ttttttgaga cagagtctca ctatgttgcc caggcttgag cgcagtggca     5400

ccatctcggc tcactacaac ctccgcctcc cagattcaag cgattttcct gcctcagcct     5460

cccaagtagc tgggattaca ggtgcccacc accatgcctg gcttaatttt ttgtattttt     5520

agtagagatg aggtttcacc atgttggcca gactggtctc gaactcctga cctcaaatga     5580

tccgctgtct tgtcctccca aagtgctggg attataggcg tgagccatcg cgccctgctg     5640

catttcattt ttttgtataa aatttggttt gttcgttttt gaggggaacc attcctttat     5700

gttgcccctt actgatgccc aactaatgtg tttctggtta ctaacagacc ttcatccccc     5760

accctcccta aattcttcgg tgtaatctaa gcgttatctg caccacttct gaataataaa     5820

tgtgtttgaa atgcacacct acacaaccct gtcccacact ggcctgtagg acctaatcta     5880

ccttcatgtc tttcagttga tttgtatttc tgcaaaagat atttcaagga ttatcaaggt     5940

atggaatttt ttttattttt tatcttttaa caaacttgtt catttccttt tctttccatt     6000

gagcacctct gaacaatgtg attctttttt ttaagtcttt cacacttcag gaaaatacta     6060

cattcaccca cgttgtgatt catatcggac agtttcttac tcaaagataa cacaaatacc     6120

aattcttatt catactttga aactatattt taccctagac tgccttggtt caaaggccta     6180

gtttcgacat tactgtggca aattatttaa gctctctgtt ttcatttctt tttctgtaaa     6240

tgcaggatga aaacaatatg tatctcctag gatggctgtg aggagtgagt gagacaggac     6300

atgaaaggtg tgtatgaact gtgataactg ttgcccttgt gggcatgtta tatagggctg     6360

gctctaggaa gaagcctgtg tcttttttca gaaatccctg gagcaactta aatgtcttta     6420

gaaatgacaa gtctctcagt tatccagtta gccgtaaaca ggttctggaa gacacaccta     6480

gatagaactc ggcccgtcag ttctgagtga ggcacgtacc acttgggctt gggatgtcct     6540

taacccattt atgcctgagg ttgcaatttt ttgaattttt ccaatcacac cttggcgatg     6600

accttgagca gtaggatata aataactccc acatgcttag tgttccaata atggaacact     6660

aggcataaac aggttttaat tggctcctca gtcaaccatg accaatatct ctatctcagc     6720

ttctgctgat gccctagctc agggctctgc attccgtgcc agggacgcct cagcccctta     6780

acatggatgt gccacatgac aggcaataat atattggccc cattagccct tcctggagca     6840

gtcataatga attacagtca tgacaggcac atgtaagaaa ccaaaatttg ctaaatatgt     6900

acatgagtct tcatcacagc atcgtttatg aaaacaacta aatattcact aatggtgcca     6960

gtggaataaa tcagagaaca tcccctgcta cgtaactctc tgcatacatc aaagagaatg     7020

gtgtggcttt gctttttcaa caatctactg agtggccatg ggcatgtgga tatggccatg     7080

aatgagcaag atcctctctg atcctgtaga agttaagttc taccagataa cttgctgctt     7140

caacaaaaag atttaccttt ttaaataaat gttgtagaat acttaaaaaa aacaaactag     7200

aatttgcctg tgtgcagcca gtaacatgtc tatttaacct ggacaccttt tgaggaatat     7260

tctcagattg cccccatgct gtttataaga cattgttcct tatacacctg tttatgaatg     7320

aaaagaaaca taaggagtgg gtacaaagac ttctatctat gaatgattaa aaaggctaga     7380

gtacgaatac ttcttgaacc tttggtacta aatgcttttc atgttctata taaatgtaga     7440

aaacatttta caaatcctgt aaataaactg tttatttttt atagaaagcc aaaaaaaa       7498


<210>  1713
<211>  6382
<212>  DNA
<213>  homo sapiens

<400>  1713
gcgcttgttt ttcccttggg acccgggtcc acacggcggg gtcgcccgtc catctccggc       60

tcgcccgcgg ggcccatcgt cgacgttagc ggccgttctc cgagccgact gacccatcct      120

tggcgctgcc gccgcgcgct tgttctcctc cctcgccccg ccttcatcct ccccgttcac      180

ggaaacgaca gctgcggctg cggggctggc gccgcctccc tccacctacc acgtctgccc      240

tcgccgctct agccctgcgc cccagcccgg ccgcggcacc tccgcctcgc cgccgctagg      300

tcggccggct ccgcccggct gccgcctagg atgaatatca tggacttcaa cgtgaagaag      360

ctggcggccg acgcaggcac cttcctcagt cgcgccgtgc agttcacaga agaaaagctt      420

ggccaggctg agaagacaga attggatgct cacttagaga acctccttag caaagctgaa      480

tgtaccaaaa tatggacaga aaaaataatg aaacaaactg aagtgttatt gcagccaaat      540

ccaaatgcca ggatagaaga atttgtttat gagaaactgg atagaaaagc tccaagtcgt      600

ataaacaacc cagaactttt gggacaatat atgattgatg cagggactga gtttggccca      660

ggaacagctt atggtaatgc ccttattaaa tgtggagaaa cccaaaaaag aattggaaca      720

gcagacagag aactgattca aacgtcagcc ttaaattttc ttactccttt aagaaacttt      780

atagaaggag attacaaaac aattgctaaa gaaaggaaac tattgcaaaa taagagactg      840

gatttggatg ctgcaaaaac gagactaaaa aaggcaaaag ctgcagaaac tagaaattca      900

tctgaacagg aattaagaat aactcaaagt gaatttgatc gtcaagcaga gattaccaga      960

cttctgctag agggaatcag cagtacacat gcccatcacc ttcgctgtct gaatgacttt     1020

gtagaagccc agatgactta ctatgcacag tgttaccagt atatgttgga cctccagaaa     1080

caactgggaa gttttccatc caattatctt agtaacaaca atcagacttc tgtgacacct     1140

gtaccatcag ttttaccaaa tgcgattggt tcttctgcca tggcttcaac aagtggccta     1200

gtaatcacct ctccttccaa cctcagtgac cttaaggagt gtagtggcag cagaaaggcc     1260

agggttctct atgattatga tgcagcaaac agtactgaat tatcacttct ggcagatgag     1320

gtgatcactg tgttcagtgt tgttggaatg gattcagact ggctaatggg ggaaagggga     1380

aaccagaagg gcaaggtgcc aattacctac ttagaactgc tcaattaagt aggtggacta     1440

tggaaaggtt gcccatcatg actttgtatt tatatacaat taactctaaa taaagcaggt     1500

taagtatctt ccatgttaat gtgttaagag actgaaaata ccagccatca gaaactggcc     1560

tttctgccaa taaagttgca tggtaaatat ttcattacag aatttatgtt agagctttca     1620

tgccaagaat gttttcttac aaaattctct ttttattgag gtttcactaa taagcagctt     1680

ctacttttga gcctcaactt aaagcagaac tgttttctac tggatttttc attaacagca     1740

agctttttct tttatgtaaa ataaatctat tgtgaattga tatcagcgac tcatttatta     1800

ggtataaata atagccaaag aataaaatta aaatttattt taaactttcg gtcttaaaaa     1860

gagctgtagg atataaacct cttttgtgaa aagtagaatt ttctgaatgc tttcatagac     1920

aaaaacgcat ttaaactatg tttacctggt tttccaacag aaatcaaatg attttaatat     1980

tatgttttga tgggttattt tcagagttgt ttggtttttt aaacactact gaatggtttc     2040

ttttaaattt aagaacaact agttcttgaa aagcaatacc gtatttctct gataaatttg     2100

tagttaaggt tctagaaaat ctaggacaaa tttacttcat taaacataaa gtttttaaga     2160

ttattcagtt ggcacaattt aatgcataat tgggattgga tccatttact gtactgtggt     2220

acagtaaaga gaatgtgttc ttattgaaca gcagatttgt atacaaatac ggaataatgc     2280

aactacatta taaattgtat acgaacaaaa taaattgggt cactctgagc ttactattaa     2340

aacattgaaa atttattaat gaacacaggc tatcttgatg aggatctctg cttatgaaac     2400

acatactaat gaaattatta gtgacacatt ggaagctaga aaattgctgt tggggccatt     2460

gctataaatc attgtttcca tgttaagact tctgttctaa ttcattcatt caacaaacat     2520

ttgttgaggg ccagatactg tgctggtcaa ctggggatac tgtcctgaac aatatgcaca     2580

cagttcttgc ccctgcagag cttaaagacc attaaaggat acagaaaatt aagcaattat     2640

cctatagtag gattcgtggt gtgatgggga aaatacaagg tactgtattt gggagtcatg     2700

taactccagt tttgggagtg agagagggtc tggggaagaa ctgttccaga taaaaagatg     2760

tgtaaccaag atagcatagc acattctgac aactaaagca atttactcta acttaagcat     2820

gaagtacaaa agtatagttc atttattgag ggaatgttaa gctattaaaa tgatactttt     2880

tggtactttt aaaaaaatga atacttaaac accgttttaa aattttgtgt taagagctcc     2940

taataagaac ttggtaaaca tgttgacaat ttaactcaca gtctaaactt taaaagtagt     3000

agttaccctt ttatttctgt gccatgagac aaattcttct gcagttttat agttgtacaa     3060

gatgttttga ctcactctca attgccatat tcttaaagaa accctgaaaa gctgctcaag     3120

ctggtcagtt ttctgtaaaa ccaagtaaat gaaattttct ctcccctcag aaaggaagtt     3180

ctacagccta gagtaccatc tattgtgttt tataagtcca gatttaggct ttgaaagatc     3240

ataccaaaac ttcagatcga cttaaacagc aactatgaat taggtttatg ggaaatgtag     3300

taatacaggg gaaagaatat cggtaatgga gtgaaatggt cctgggttca aatccagtct     3360

tcctcacata ttgtgctctt taagcttcaa atgagatgta taactgcctt ttccttacca     3420

gtaaaatgag gacaataatt atgacaccat agggtggttg tgaggattag caaatgttat     3480

cttgtatttc aggtgccttt cagggaaagg cttggcacat agtaaacaca tcctgtaaat     3540

atcagtttcc ccttgttagc ccctgtagca tcctgaccta ccaagtctat aggccttgca     3600

tatcactgtg caccagagat acctctttta catctgggct ctgttttctc tctatcaatc     3660

ctatcctcca ccctctttaa atcagacccc aggtttaacc ttcccacagt cagtataaat     3720

catttttcag aactttcagc tttccatcaa gtgaaagttg attttagtta cccagtaatg     3780

tacagaaacc ttcaataatg ttaagcttca aaggcttctg gtacgtttgt ctaccacaga     3840

accaccacaa tatatatgct tgttcttagg tttattgctt tttattttaa tggggtttgg     3900

ttgtttgggt tttattttgg ttttggctta ttttaaagtc aagtttagtt tttactcagg     3960

taaaggcctg aagtttcttg ggcgtggaag aaaaagcttg ggaagcctat taattcatgg     4020

tgcagttcag aattgtttaa ataagctctg tgccactgag cttaatctga aagtatagtg     4080

acatgtgaag gatgcacata tgaatgaaaa actaaaataa ttgtaggctc ttctataaat     4140

gaaaaaaaaa gtgattggat tgtgtctacc tttttcctca aagtaatcta acctaaacgg     4200

tcatggtgtt aaaacttttt atggtgctaa tcagaaaaat tgatgttgca agaaatgagg     4260

tctcaaaaat gggaatgtgc ctcctcactc tgcgtcacat gggaaataaa tcctgaggcc     4320

aggatcacca gtggggtaga gtcatcttca tagtctcctg ttatcctccc cctgaacaaa     4380

gaacaaagtg agactgggaa gctagtgttg gggaaacatt tctgggataa actgtggagt     4440

ggagaagaca atggagggca aggcaaaaac ccacagactt gtttacccat agaggcccca     4500

ctcacctcca tgctgacaga attccagaaa aattccttcc ctatctccca aacacctgaa     4560

attctgaaat attgccctac tatttagcac tttaagcttc agtgaggtgc tgtaatggag     4620

agatagcttc atagtttagc ctatagccaa ctttgcctca agacctccag ataagatgaa     4680

gtggctttta cctcatgtga gtctcaaacg ctggagagag agttccacaa ccacccctgc     4740

cctttctccc atattacgct cattagaaag tctactcagg gctgggtgcc gtggctcatg     4800

cctgtaatcc cagcactttg gaggctgagg cgggtggatc atctgaggtc aggagttcga     4860

gaccagcctg gccaacatgg ggaaaccctg tctctactga aaatataaaa attagccggg     4920

catggtggcg tgcacctgta attccagcta ctcgggaggc tgaggcagga gaatcacttg     4980

aaccccagag gcagaggcta cagtgagcca agattgcacc actgcactcc aacctgggtg     5040

atagaataag actcttgtct caaggaaaga aaaaatgtct actcagtaga gcagtgattg     5100

gcaaagtgtg agaccccaga ccggcaatat tggcatctcc tggagacttg tttaaaatgc     5160

tgattactat tttcaagaac tttctacctt catttttact tattttttgt tttcaagggc     5220

tcatggaatc agtcttccat gtgacagctt tttaaatatt ttaagacaaa aactgagtct     5280

tctaatctta attgtgttct agcagtagtc attgtaatta tagttatttt tataatttat     5340

ttgtttagtg tatatctgtc actctagaat gtaggctccc tgagataaaa actataattc     5400

ttttgatggc agttacattc ccaactctta gcacaagatc taggacatag tatgaactca     5460

ataaattttt gttgaatgaa agaaaaatgc aaatttataa gccttttcag agacctactg     5520

aatcaaactc tgagagtgga gcccagcaat ctgttgtaaa agctgtttga gtaatactgt     5580

tgcactctaa gcttgagaac cactgcaata gaactaagag aacattcatt tcaccttcag     5640

gcctattctc tgacatcact tgaaaaatcc tctctgcctt ctgtaaccct taaccaacaa     5700

cagtgccctg tccatgtagg ggaaacttct gggctgtatt acaagtgggt aggaaggtat     5760

aaggatatca tagtgggaag tattgcttag aatgccagta cttgtttgct gtggaaggtt     5820

tctaggaatg gattgcttag tctaaagtaa gcactaccac catccacgtt ttcactcaac     5880

acagtgcctt ttaattggtg actaacatca aaacaccttg acaaaccgtt aaaacagtat     5940

cagaaaccat gtgtacatcc ctgtgcctct tagattgcta agttctgctc tcattcttac     6000

ttcaaaggac actttttaaa gaattgttaa tgctttttta taatacaagt catagccctg     6060

ttggcaaaaa gaaaaaagat tcagtgagaa agaaaaatca ctgataattc catcatccag     6120

ggagaaccac tgttatttaa gtatatggcc ttccagactt ttctgtgcat ttatagatat     6180

ttttaatggg atcaaagtgt acatactgtt ttgtaacttt ttttcactca acaataccat     6240

gactgtcttg ctgtgtcaag tatatttcta catctcttaa tggctgcatg atattccatc     6300

atatgtgcca cattttatta aactactgtt caatttttag gtttccaact ttcattaata     6360

aagtgcttta aagaacaaaa aa                                              6382


<210>  1714
<211>  3426
<212>  DNA
<213>  homo sapiens

<400>  1714
taaatggcag ccaatggagg gtggtgttgc gcggggctgg gattagggcc ggggcgaatg       60

gctggcaatc ttactgggat tacagaacaa agagcctccc cgcgctcccg ctctccgctc      120

ctctccccgc gccgccccgc cctccgccgc agcccgcgcc gggggtgggg gccgccgagc      180

gccagccccc cggccggccg attccccccc cgcgccccct ccccgcgcct ccctccccgc      240

cctcgccgcg ccgccgtcct cgcctccctc tgcctctcct tcccccattc tcccggatta      300

attaaggagg cagcggcagg aggctgagtc ctggccgcgg gccggggccg gggcgccgct      360

ggcaggagcg cttggggatc ctccaaggcg accatggcct tgctgggtaa gcgctgtgac      420

gtccccacca acggctgcgg acccgaccgc tggaactccg cgttcacccg caaagacgag      480

atcatcacca gcctcgtgtc tgccttagac tccatgtgct cagcgctgtc caaactgaac      540

gccgaggtgg cctgtgtcgc cgtgcacgat gagagcgcct ttgtggtggg cacagagaag      600

gggagaatgt tcctgaatgc ccggaaggag ctacagtcag acttcctcag gttctgccga      660

gggcccccgt ggaaggatcc ggaggcagag caccccaaga aggtgcagcg gggcgagggt      720

ggaggccgta gcctccctcg gtcctccctg gaacatggct cagatgtgta ccttctgcgg      780

aagatggtag aggaggtgtt tgatgttctt tatagcgagg ccctgggaag ggccagtgtg      840

gtgccactgc cctatgagag gctgctcagg gagccagggc tgctggccgt gcaggggctg      900

cccgaaggcc tggccttccg aaggccagcc gagtatgacc ccaaggccct catggccatc      960

ctggaacaca gccaccgcat ccgcttcaag ctcaagaggc cacttgagga tggcgggcgg     1020

gactcgaagg ccctggtgga gctgaacggt gtctccctga ttcccaaggg gtcacgggac     1080

tgtggcctgc atggccaggc ccccaaggtg ccaccccagg acctgccccc aaccgccacc     1140

tcctcctcca tggccagctt cctgtacagc acggcgctcc ccaaccacgc catccgagag     1200

ctcaagcagg aagcaccttc ctgccccctt gcccccagcg acctgggcct gagtcggccc     1260

atgccagagc ccaaggccac cggtgcccaa gacttctccg actgttgtgg acagaagccc     1320

actgggcctg gtgggcctct catccagaac gtccatgcct ccaagcgcat tctcttctcc     1380

atcgtccatg acaagtcaga gaagtgggac gccttcataa aggaaaccga ggacatcaac     1440

acgctccggg agtgtgtgca gatcctgttt aacagcagat atgcggaagc cctgggcctg     1500

gaccacatgg tccccgtgcc ctaccggaag attgcctgtg acccggaggc tgtggagatc     1560

gtgggcatcc cggacaagat ccccttcaag cgcccctgca cttatggagt ccccaagctg     1620

aagcggatcc tggaggagcg ccatagtatc cacttcatca ttaagaggat gtttgatgag     1680

cgaattttca cagggaacaa gtttaccaaa gacaccacga agctggagcc agccagcccg     1740

ccagaggaca cctctgcaga ggtctctagg gccaccgtcc ttgaccttgc tgggaatgct     1800

cggtcagaca agggcagcat gtctgaagac tgtgggccag gaacctccgg ggagctgggc     1860

gggctgaggc cgatcaaaat tgagccagag gatctggaca tcattcaggt caccgtccca     1920

gacccctcgc caacctctga ggaaatgaca gactcgatgc ctgggcacct gccatcggag     1980

gattctggtt atgggatgga gatgctgaca gacaaaggtc tgagtgagga cgcgcggccc     2040

gaggagaggc ccgtggagga cagccacggt gacgtgatcc ggcccctgcg gaagcaggtg     2100

gagctgctct tcaacacacg atacgccaag gccattggca tctcggagcc cgtcaaggtg     2160

ccgtactcca agtttctgat gcacccggag gagctgtttg tggtgggact gcctgaaggc     2220

atctccctcc gcaggcccaa ctgcttcggg atcgccaagc tccggaagat tctggaggcc     2280

agcaacagca tccagtttgt catcaagagg cccgagctgc tcactgaggg agtcaaagag     2340

cccatcatgg atagtcaaga gagggattcc ggggaccctc tggtggacga gagcctgaag     2400

agacagggct ttcaagaaaa ttatgacgcg aggctctcac ggatcgacat cgccaacaca     2460

ctaagggagc aggtccagga ccttttcaat aagaaatacg gggaagcctt gggcatcaag     2520

tacccggtcc aggtccccta caagcggatc aagagtaacc ccggctccgt gatcatcgag     2580

gggctgcccc caggaatccc gttccgaaag ccctgtacct tcggctccca gaacctggag     2640

aggattcttg ctgtggctga caagatcaag ttcacagtca ccaggccttt ccaaggactc     2700

atcccaaagc ctgatgaaga tgacgccaac agactcgggg agaaggtgat cctgcgggag     2760

caggtgaagg aactcttcaa cgagaaatac ggtgaggccc tgggcctgaa ccggccggtg     2820

ctggtccctt ataaactaat ccgggacagc ccagacgccg tggaggtcac gggtctgcct     2880

gatgacatcc ccttccggaa ccccaacacg tacgacatcc accggctgga gaagatcctg     2940

aaggcccgag agcatgtccg catggtcatc attaaccagc tccaaccctt tgcagaaatc     3000

tgcaatgatg ccaaggtgcc agccaaagac agcagcattc ccaagcgcaa gagaaagcgg     3060

gtctcggaag gaaattccgt ctcctcttcc tcctcgtctt cctcttcctc gtcctctaac     3120

ccggattcag tggcatcggc caaccagatc tcactcgtgc aatggccaat gtacatggtg     3180

gactatgccg gcctgaacgt gcagctcccg ggacctctta attactagac ctcagtactg     3240

aatcaggacc tcactcagaa agactaaagg aaatgtaatt tatgtacaaa atgtatattc     3300

ggatatgtat cgatgccttt tagtttttcc aatgattttt acactatatt cctgccacca     3360

aggccttttt aaataagtaa aaaaagaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaa                                                                3426


<210>  1715
<211>  3261
<212>  DNA
<213>  homo sapiens

<400>  1715
ttggctggga agaggtggca atcagggcgg gccaaggcgg ctgttctcgc tccagctcga       60

tgctgcctcc ccggcccggt tgcgctgtag ccgctgccgc ctctgcctgg gtcccttcgg      120

ccgtacctct gcgtgggggc tgcctccccg gctcccggtg cagacaccat gtacggattt      180

gtgaatcacg ccctggagtt gctggtgatc cgcaattacg gccccgaggt gtgggaagac      240

atcaaaaaag aggcacagtt agatgaagaa ggacagtttc ttgtcagaat aatatatgat      300

gactccaaaa cttatgattt ggttgctgct gcaagcaaag tcctcaatct caatgctgga      360

gaaatcctcc aaatgtttgg gaagatgttt ttcgtctttt gccaagaatc tggttatgat      420

acaatcttgc gtgtcctggg ctctaatgtc agagaatttc tacagaacct tgatgctctg      480

cacgaccacc ttgctaccat ctacccagga atgcgtgcac cttcctttag gtgcactgat      540

gcagaaaagg gcaaaggact cattttgcac tactactcag agagagaagg acttcaggat      600

attgtcattg gaatcatcaa aacagtggca caacaaatcc atggcactga aatagacatg      660

aaggttattc agcaaagaaa tgaagaatgt gatcatactc aatttttaat tgaagaaaaa      720

gagtcaaaag aagaggattt ttatgaagat cttgacagat ttgaagaaaa tggtacccag      780

gaatcacgca tcagcccata tacattctgc aaagcttttc cttttcatat aatatttgac      840

cgggacctag tggtcactca gtgtggcaat gctatataca gagttctccc ccagctccag      900

cctgggaatt gcagccttct gtctgtcttc tcgctggttc gtcctcatat tgatattagt      960

ttccatggga tcctttctca catcaatact gtttttgtat tgagaagcaa ggaaggattg     1020

ttggatgtgg agaaattaga atgtgaggat gaactgactg ggactgagat cagctgctta     1080

cgtctcaagg gtcaaatgat ctacttacct gaagcagata gcatactttt tctatgttca     1140

ccaagtgtca tgaacctgga cgatttgaca aggagagggc tgtatctaag tgacatccct     1200

ctgcatgatg ccacgcgcga tcttgttctt ttgggagaac aatttagaga ggaatacaaa     1260

ctcacccaag aactggaaat cctcactgac aggctacagc tcacgttaag agccctggaa     1320

gatgaaaaga aaaagacaga cacattgctg tattctgtcc ttcctccgtc tgttgccaat     1380

gagctgcggc acaagcgtcc agtgcctgcc aaaagatatg acaatgtgac catcctcttt     1440

agtggcattg tgggcttcaa tgctttctgt agcaagcatg catctggaga aggagccatg     1500

aagatcgtca acctcctcaa cgacctctac accagatttg acacactgac tgattcccgg     1560

aaaaacccat ttgtttataa ggtggagact gttggtgaca agtatatgac agtgagtggt     1620

ttaccagagc catgcattca ccatgcacga tccatctgcc acctggcctt ggacatgatg     1680

gaaattgctg gccaggttca agtagatggt gaatctgttc agataacaat agggatacac     1740

actggagagg tagttacagg tgtcatagga cagcggatgc ctcgatactg tctttttggg     1800

aatactgtca acctcacaag ccgaacagaa accacaggag aaaagggaaa aataaatgtg     1860

tctgaatata catacagatg tcttatgtct ccagaaaatt cagatccaca attccacttg     1920

gagcacagag gcccagtgtc catgaagggc aaaaaagaac caatgcaagt ttggtttcta     1980

tccagaaaaa atacaggaac agaggaaaca aagcaggatg atgactgaat cttggattat     2040

ggggtgaaga ggagtacaga ctaggttcca gttttctcct aacacgtgcc aagcccagga     2100

gcagttcttc cctatggata cagattttct tttgtccttg tccattaccc caagactttc     2160

ttctagatat atctctcact atccgttatt caaccttagc tctgctttct attacttttt     2220

aggctttagt atattatcta aagtttggct tttgatgtgg atgatgtgag cttcatgtgt     2280

cttaaaatct actacaagca ttacctaaca tggtgatctg caagtagtag gcacccaata     2340

aatatttgtt gaatttagtt aaatgaaact gaacagtgtt tggccatgtg tatatttata     2400

tcatgtttac caaatctgtt tagtgttcca catatatgta tatgtatatt ttaatgacta     2460

taatgtaata aagtttatat catgttggtg tatatcatta tagaaatcat tttctaaagg     2520

agtgaattct aagttttagg ggaaaaaatg caatttattt tcagactccc aaagtaagaa     2580

ttaacatatc atgctaagaa aatagtgact attttgaagt atgctacttc cctttcagaa     2640

atatagaata cacgtttctg ttattaaagt atttgattac taattcaaat catatggcaa     2700

ttataattct tctaaaatgc tatcatttgt aactgtatcc cctgtattaa atctcattaa     2760

ccacaggcag ctgttacaga aagctgcatt gtttcacatt gagctgttac attagttcag     2820

gctaaatgtt gggagctcca accacatcca agaataaatc tggaaacaca ctgctgggat     2880

actgctgtta gagcccttct tggccttgta ttcccagaaa tgagctccct ttccttagct     2940

tagaagaatg tgattatatc caggacatca tgttcagaaa acttagttta ctttcagcat     3000

agaatgcatt actgttggaa taattggcct ctagctctta aatgtctctg ataacttatt     3060

aatatctatc tttataaaat agagtgcaac tacttttgtg taaaaatgtt tgcctttaaa     3120

tttagtattt catatcagca catcgatata tgtataaatg ttccatgtta atgtgtaaaa     3180

gagtctgtaa taaattattt ttttcacgtg tctctataca gtttttattt caataaaaat     3240

attaacatta tttttcattt t                                               3261


<210>  1716
<211>  3318
<212>  DNA
<213>  homo sapiens

<400>  1716
cgcgggcttg cgggcagggg ctgcagggag gaggagagga cccgcgcccg cgggggctgg       60

cggaggcggg gccgggcttc cggacagagg ccaatcgctg ccctcggggc ctccagcgcc      120

ggctctgggc cgaggcagcc agagcgcgga agaggcctgg aaatccacgc ggattcccgg      180

agacggcgcc tctgctctgc gggttcgtgg cgaggaagtc cacccactgc tcccgggcgc      240

aggtctgcag gtccgcgccc actgcccgcg gcgccactga ccatgtcggt gactgatcag      300

gcttttgtca cactagccac caatgacatc tactgccagg gcgccctggt cctggggcag      360

tcactgagga gacacaggct gacgaggaag ctggtggtgt tgatcactcc tcaggtgtcc      420

agcctgctca gggtcatcct ctcgaaggtg ttcgatgaag tcattgaagt gaatctaatc      480

gatagtgccg actacatcca cctggccttt ctgaagagac ctgagctcgg gctcaccctc      540

accaagcttc actgttggac tctcactcac tacagcaagt gtgtcttcct ggatgcagac      600

actctggtgc tgtccaatgt cgatgagctg tttgacaggg gagagttttc tgcggccccg      660

gaccccggat ggccggattg cttcaatagc ggggtgtttg tcttccagcc ttctctccac      720

acgcataaac tcctgctaca gcacgccatg gaacacggca gctttgacgg ggcagaccaa      780

ggcttactga atagtttctt caggaactgg tcgaccacag acatccacaa gcacctgccg      840

ttcatctata acttgagtag taacacgatg tacacttaca gccctgcctt caagcaattc      900

ggttccagtg caaaggtcgt ccactttttg gggtccatga aaccttggaa ctacaagtac      960

aatccacaga gtggctcggt gttggagcaa ggctcagcgt ccagcagcca gcaccaggcg     1020

gcattccttc atctctggtg gacggtctac cagaacaacg tgctgcccct ttataaaagc     1080

gtccaagcgg gggaagcacg cgcgtctcct ggtcacacac tttgccacag tgatgtgggg     1140

gggccgtgtg cggattcagc ctctggtgtt ggagagccgt gtgaaaattc aacacccagt     1200

gcgggcgtgc cgtgtgcaaa ttcaccactg ggttctaacc agcctgctca gggccttccg     1260

gagccgaccc agatagtgga tgagaccctg tccctacctg aaggacgccg ttcagaagat     1320

atgatagctt gtcctgaaac tgagactcct gccgtgataa cgtgtgaccc actgtcccag     1380

ccttcccctc agcctgcaga cttcacagag actgaaacca tcttgcagcc agcaaataaa     1440

gtcgaaagtg tctcatccga ggaaaccttc gaaccaagcc aggaactccc tgctgaggct     1500

ctcagggacc ccagtctgca ggatgcactg gaggtcgacc tggccgtctc tgtttcccag     1560

atctccatcg aagagaaggt gaaggaattg agccccgagg aagagaggag gaagtgggag     1620

gaaggccgta tcgactacat ggggaaggac gcgtttgctc gcatccagga gaagctggac     1680

cggttcctgc agtaatccgg cagctggtgg gcgttgtgtg tagttagaca atgtcctgtt     1740

gggtggtcct gttgcgtgga gatctcctct ggtcctttca aagggaaacg ctgttgaacc     1800

ttgtgcctct atttatgctt aatccatttg agtgcctcac acaaaaaacg tagagtatag     1860

aaatccacct taaagcccct cgccccaact tctccaccaa cgccttctgg gctttcttca     1920

gaggtcactt ctacccttga agctgtcggc aaaagcgagc agtaataaca ttctagtaga     1980

ctctcgatgg tggtctccgc tcttgcccga aggacctctg aagtacgctg gagctgtgtt     2040

gtacaggtgc tgtgagacct accctattca gaattaaacc tcactgcaaa tttcctccca     2100

tcacgaagct aacaacacta atatacgtat ttagcacctc tgaggctttg ccatggagac     2160

ccatttctgt agggctaagg aaacatttag acgtggtgac tgactttcat ttggacttgg     2220

cgaagtgtat ctgagaaaca cctcggctgt ggtctctctg ctttaaatcc taacaggact     2280

tcctagagcg ttgacagaaa ttctactcgt ggacgttggg aagaaagatt gtaggtggct     2340

tggggaatgt gggtggctta gaggatctaa accgattcac ttcctggttg agaagcaacg     2400

agggcttgct ctaaatcgtt tagaggataa caggatctag agatgctctc tgcttgacaa     2460

caaaagtcag ggtgcagtcg gtccaccctt gactgctctt ggcttggtct ctaccctcac     2520

tacctcagtt ctcaataact tagtgaatca ctgccctcct caaagccatt tccactcagc     2580

tctttccaga gaattctcag ttttatgaga cgggaaactt tatttcacga gaaagcctca     2640

ttgtcagaag tatcttcatt caatgggcac aatatgctgt gtatctcacc aggtagctgt     2700

caggggccac cgagagtgtc gttaaaaatg ggcatggttg taataaagga ggaaagtgcg     2760

acttttgaaa tgtttggaag gtttatttct catgcacatt ccagggaaaa gcagagagta     2820

aattagagac gggataggaa ggccgtggga gaactcgatc ctagcctgtg tcagctggat     2880

gtgtttacgt ggagaggcgt ggccactttt taggtcacct gaagcagttt agcctttgga     2940

tagaggaacc tgcctgaatt tatggcatta gtggtggcat ttttttgtgt acaagatgtg     3000

ggtgatggag gggctgtttc tttttccgtg tgggtggtta ataatcgtca gtctcggagg     3060

gcgaggctcg taggatattt caggtgagtc agggttggat ggtcatcggc tttcagaagg     3120

agaccacggg aatgttcagg gaaacaatgt cagcttctct gaggaccaga attcatgttc     3180

acgggcagtg atgagttggc ttatggagtg agtccagtct ggaattccgc cgtgcattct     3240

agcctgtatc atctcatttg gacaaatgct ggcacgttga aattaaaatg ttaaaaaaca     3300

gcaaaaaaaa aaaaaaaa                                                   3318


<210>  1717
<211>  3411
<212>  DNA
<213>  homo sapiens

<400>  1717
cgcgggcttg cgggcagggg ctgcagggag gaggagagga cccgcgcccg cgggggctgg       60

cggaggcggg gccgggcttc cggacagagg ccaatcgctg ccctcggggc ctccagcgcc      120

ggctctgggc cgaggcagcc agagcgcgga agaggcctgg aaatccacgc ggattcccgg      180

agacggcgcc tctgctctgc gggttcgtgg cgaggaagtc cacccactgc tcccgggcgc      240

aggtctgcag gtccgcgccc actgcccgcg gcgccactga ccatgtcgga gacagagttt      300

caccatggtg cccaggctgg tctcgaactc ctgaggtcaa gcaattcacc cacctcagcc      360

tcccaaagtg ctggaatgac agtgactgat caggcttttg tcacactagc caccaatgac      420

atctactgcc agggcgccct ggtcctgggg cagtcactga ggagacacag gctgacgagg      480

aagctggtgg tgttgatcac tcctcaggtg tccagcctgc tcagggtcat cctctcgaag      540

gtgttcgatg aagtcattga agtgaatcta atcgatagtg ccgactacat ccacctggcc      600

tttctgaaga gacctgagct cgggctcacc ctcaccaagc ttcactgttg gactctcact      660

cactacagca agtgtgtctt cctggatgca gacactctgg tgctgtccaa tgtcgatgag      720

ctgtttgaca ggggagagtt ttctgcggcc ccggaccccg gatggccgga ttgcttcaat      780

agcggggtgt ttgtcttcca gccttctctc cacacgcata aactcctgct acagcacgcc      840

atggaacacg gcagctttga cggggcagac caaggcttac tgaatagttt cttcaggaac      900

tggtcgacca cagacatcca caagcacctg ccgttcatct ataacttgag tagtaacacg      960

atgtacactt acagccctgc cttcaagcaa ttcggttcca gtgcaaaggt cgtccacttt     1020

ttggggtcca tgaaaccttg gaactacaag tacaatccac agagtggctc ggtgttggag     1080

caaggctcag cgtccagcag ccagcaccag gcggcattcc ttcatctctg gtggacggtc     1140

taccagaaca acgtgctgcc cctttataaa agcgtccaag cgggggaagc acgcgcgtct     1200

cctggtcaca cactttgcca cagtgatgtg ggggggccgt gtgcggattc agcctctggt     1260

gttggagagc cgtgtgaaaa ttcaacaccc agtgcgggcg tgccgtgtgc aaattcacca     1320

ctgggttcta accagcctgc tcagggcctt ccggagccga cccagatagt ggatgagacc     1380

ctgtccctac ctgaaggacg ccgttcagaa gatatgatag cttgtcctga aactgagact     1440

cctgccgtga taacgtgtga cccactgtcc cagccttccc ctcagcctgc agacttcaca     1500

gagactgaaa ccatcttgca gccagcaaat aaagtcgaaa gtgtctcatc cgaggaaacc     1560

ttcgaaccaa gccaggaact ccctgctgag gctctcaggg accccagtct gcaggatgca     1620

ctggaggtcg acctggccgt ctctgtttcc cagatctcca tcgaagagaa ggtgaaggaa     1680

ttgagccccg aggaagagag gaggaagtgg gaggaaggcc gtatcgacta catggggaag     1740

gacgcgtttg ctcgcatcca ggagaagctg gaccggttcc tgcagtaatc cggcagctgg     1800

tgggcgttgt gtgtagttag acaatgtcct gttgggtggt cctgttgcgt ggagatctcc     1860

tctggtcctt tcaaagggaa acgctgttga accttgtgcc tctatttatg cttaatccat     1920

ttgagtgcct cacacaaaaa acgtagagta tagaaatcca ccttaaagcc cctcgcccca     1980

acttctccac caacgccttc tgggctttct tcagaggtca cttctaccct tgaagctgtc     2040

ggcaaaagcg agcagtaata acattctagt agactctcga tggtggtctc cgctcttgcc     2100

cgaaggacct ctgaagtacg ctggagctgt gttgtacagg tgctgtgaga cctaccctat     2160

tcagaattaa acctcactgc aaatttcctc ccatcacgaa gctaacaaca ctaatatacg     2220

tatttagcac ctctgaggct ttgccatgga gacccatttc tgtagggcta aggaaacatt     2280

tagacgtggt gactgacttt catttggact tggcgaagtg tatctgagaa acacctcggc     2340

tgtggtctct ctgctttaaa tcctaacagg acttcctaga gcgttgacag aaattctact     2400

cgtggacgtt gggaagaaag attgtaggtg gcttggggaa tgtgggtggc ttagaggatc     2460

taaaccgatt cacttcctgg ttgagaagca acgagggctt gctctaaatc gtttagagga     2520

taacaggatc tagagatgct ctctgcttga caacaaaagt cagggtgcag tcggtccacc     2580

cttgactgct cttggcttgg tctctaccct cactacctca gttctcaata acttagtgaa     2640

tcactgccct cctcaaagcc atttccactc agctctttcc agagaattct cagttttatg     2700

agacgggaaa ctttatttca cgagaaagcc tcattgtcag aagtatcttc attcaatggg     2760

cacaatatgc tgtgtatctc accaggtagc tgtcaggggc caccgagagt gtcgttaaaa     2820

atgggcatgg ttgtaataaa ggaggaaagt gcgacttttg aaatgtttgg aaggtttatt     2880

tctcatgcac attccaggga aaagcagaga gtaaattaga gacgggatag gaaggccgtg     2940

ggagaactcg atcctagcct gtgtcagctg gatgtgttta cgtggagagg cgtggccact     3000

ttttaggtca cctgaagcag tttagccttt ggatagagga acctgcctga atttatggca     3060

ttagtggtgg catttttttg tgtacaagat gtgggtgatg gaggggctgt ttctttttcc     3120

gtgtgggtgg ttaataatcg tcagtctcgg agggcgaggc tcgtaggata tttcaggtga     3180

gtcagggttg gatggtcatc ggctttcaga aggagaccac gggaatgttc agggaaacaa     3240

tgtcagcttc tctgaggacc agaattcatg ttcacgggca gtgatgagtt ggcttatgga     3300

gtgagtccag tctggaattc cgccgtgcat tctagcctgt atcatctcat ttggacaaat     3360

gctggcacgt tgaaattaaa atgttaaaaa acagcaaaaa aaaaaaaaaa a              3411


<210>  1718
<211>  5220
<212>  DNA
<213>  homo sapiens

<400>  1718
gagggaaggc gcgcagacgc gcagcggccg gcctgctccg ggcgcgtcag gcagggggtg       60

gggagcaggg gccgggcggg cgctcggctc ccagccgcgc tccctcgggc cactagcgct      120

cccgcgcgcg cccggccgcc ttcatgtgaa gcgccggccc tccgcccctt ccctcccctt      180

ccttccctcc ctccctccct gtcccctcct cctcctcctc ctcctccggc gcccgcttca      240

gctccccggg gccccctgcc cggccgggcg ctgacagcaa gggcgggggt ccctgccgcc      300

gccttgtctc gcgcagggtc cggctggggt agcggagccc ccagtgcggc catggaccgg      360

cccctgtcgt cgtcggcgga ggcggaggag gaactggagt ggcaagtggc gagtcgcagg      420

aggaaggcct gggccaagtg ccgcagctcc tggcaagcgt cggagacgga ggatctgtcc      480

acagaagcga cgacgcagga cgaggaggag gacgaggagg aggacctccc cggcgcgcag      540

ctgccggcag cggggggaag aggaaacgtg cccaacgaga agatcgcgat atggctcaag      600

gactgccgta cacctttggg agcctcactg gatgaacaaa gcagtagtac actcaagggt      660

gtgcttgtga gaaatggagg aagttttgaa gatgatttgt cattgggagc tgaagccaac      720

cacctccatg aaagtgatgc tcaaattgaa aactgcaata atatcttggc caaagagaga      780

agattacagt ttcatcagaa agggagaagt atgaattcca ctggatctgg gaaaagtagt      840

gggacagttt caagtgtttc agaattgttg gaactttatg aggaagatcc tgaagaaatt      900

ctttataatc ttggatttgg acgtgatgaa ccagatattg cttctaaaat tccttccaga      960

ttttttaatt catcatcctt tgccaaaggg atagatatta aagtattttt gagtgctcag     1020

atgcaacgga tggaagtaga aaacccaaat tatgctttaa caagccgttt tcgtcaaatt     1080

gaagtgctta ctactgtggc caatgcgttt tcttctttat attctcaagt ctccgggacg     1140

cccctgcaga gaattggaag tatgtcctca gtgacctcta acaaggagac agacccacct     1200

ccacctttaa ctcgaagtaa cactgcaaat cgtttaatga aaacactctc aaaactgaat     1260

ttatgtgttg ataaaacaga gaaaggagaa agtagtagtc cttctccatc agctgaaaaa     1320

ggaaagattc taaatgtttc agtgattgaa gaaagtggca ataaaaacga tcaaaagtct     1380

caaaaaatta tgaagaagaa agagtcatct tctatgttgg ctacagttaa agaagaagtc     1440

tctggtagtt cagcagctgt tacggagaat gctgatagtg atagaatttc tgatgaagca     1500

aatagtaatt ttaaccaagg aactgaaaat gaacaaagta aagaaactca aagtcatgag     1560

agtaaactgg gtgaggaatc tggtattgta gaatccaaat tagatagtga tttcaacata     1620

tccagccaca gtgagctgga aaatagcagt gagctgaaaa gtgtccatat atccacacct     1680

gaaaaagagc cttgtgcacc actgacaata ccatccataa gaaatataat gacacagcag     1740

aaggactcct tcgaaatgga agaggttcaa agtacggagg gagaagctcc tcatgttcca     1800

gccacttacc agctaggtct tacgaagtcg aaaagagatc atctgttacg tactgcaagt     1860

cagcattccg atagcagtgg ttttgctgaa gattctacag actgcctatc ccttaatcat     1920

cttcaggttc aggagtcctt gcaggctatg gggagtagtg ctgatagttg tgacagtgag     1980

acaacagtta cgtcacttgg tgaagacctt gccacaccaa cagcacaaga ccagccttat     2040

tttaatgaat cagaggagga gtctcttgtc cctcttcaga agggactaga gaaggcagca     2100

gcagttgcag acaaaagaaa atcaggtagc caggatttcc ctcagtgcaa caccattgag     2160

aatacaggaa ctaaacagtc cacctgtagt ccaggggatc atatcattga aattactgaa     2220

gtggaagagg atttgtttcc agcagagaca gtagagctac tgagggaagc aagtgctgaa     2280

agtgatgtgg gtaaaagcag tgaaagtgaa tttactcagt ataccacaca ccatattctg     2340

aaatcattgg cttctattga agctaaatgc agtgatatga gctctgaaaa tacaactggg     2400

cctccctctt ccatggacag agttaataca gctttgcaaa gagctcaaat gaaggtttgc     2460

agtctgtcta atcaaaggat ggggcgtagc ctgctaaaat caaaagattt gttaaaacaa     2520

aggtacttat ttgcaaaagc tggctatcct ctaagaaggt ctcagtcttt accaaccacc     2580

ttattgagcc cagtaagggt tgtgtcctct gtcaatgttc gattatctcc aggaaaagag     2640

accagatgca gcccaccttc cttcacctat aagtacacac ctgaagagga gcaggaattg     2700

gaaaagcggg tgatggaaca tgatggtcag tctttagtta aatcgaccat tttcatctct     2760

ccatcatctg tgaagaaaga agaagccccc cagagtgagg cgccgcgggt ggaggaatgc     2820

catcatggaa ggactcctac ctgttcacgg cttgctccac caccaatgtc tcagtctacc     2880

tgttcccttc attccatcca ctctgagtgg caagaaaggc ccctgtgtga gcacacaaga     2940

actctgagca ctcacagtgt tcccaacata tcaggggcta cttgtagtgc cttcgcttcc     3000

cctttcgggt gtccttactc acatagacat gccacctacc cttaccgagt gtgctctgtg     3060

aatcctcctt cagccataga aatgcagttg cgaagagtat tacatgatat tagaaactca     3120

ctgcagaatc tttcacagta ccctatgatg agaggacctg atcctgctgc tgctccatat     3180

agtactcaga aatcatctgt tctacctctt tatgaaaata cttttcagga gctccaggta     3240

atgaggcgga gcctgaattt gtttagaaca caaatgatgg atttagaatt ggcaatgctg     3300

cgtcagcaaa ccatggttta tcatcatatg actgaggagg agaggtttga agttgatcag     3360

ctccagggtt tgagaaattc agtccgaatg gaacttcagg acctggaact gcagctggag     3420

gagcgcctgc tgggcctgga ggagcagctt cgtgctgtgc gcatgccttc acccttccgc     3480

tcctccgcac tcatgggaat gtgtggcagt agaagcgctg ataacttgtc atgcccttct     3540

ccattgaatg taatggaacc agtcactgaa ctgatgcagg agcagtcata cctgaagtct     3600

gaattgggcc tgggacttgg agaaatggga tttgaaattc ctcctggaga aagctcagaa     3660

tctgtttttt cccaagcaac atcagaatca tcttctgtat gttctggtcc ctctcatgct     3720

aacagaagaa ctggagtacc ttctactgcc tcagtgggca aatccaaaac cccattagtg     3780

gcaaggaaga aagtgttccg agcatcggtg gctctaacgc caacagctcc ttctagaaca     3840

ggctctgtgc agacacctcc agatttggaa agttctgagg aagttgatgc agctgaagga     3900

gccccagaag ttgtaggacc taaatctgaa gtggaagaag ggcatggaaa actcccatca     3960

atgccagctg ctgaggaaat gcataaaaat gtggagcaag atgagttgca gcaagtcata     4020

cgggaggttg gcatggatcc tattagctgt gtaatactgg aattatcaat gatatgcact     4080

ggtggaggtg ttatttgtgc tttagaagat acttgctgtt gagctgggct actgtataca     4140

gtgtacaatg tgtatttctt caaccatata ttttaaaaag acgtacatag aaacttaggc     4200

actttgctat ttcttttcta aactatcaaa aactctagca gtttgaaaag cctaatattt     4260

atttgtatgt cagtattttt catttgattc cctattagaa ttaattttaa aacttgaaga     4320

cttccagact tatccaactt ataaataaca tatttcttca gactaacatc ttaaaacact     4380

gacctctatg aggtatttac tgtgcaataa ctgattcatt tttttcagag cttgaagcat     4440

ccaatgattt ttccctccac tgctgttaat taatgtcact tccaagaaga aaaactgttc     4500

tgttgtaaaa aatataattg ctcttaattc ttggggaggt tactaatagc agtaggatag     4560

aattttatga ggttacctac aactacttaa tgtacttaca ctgtaagcct tgttgcttta     4620

cccaagacaa atgtaatttt atcattgctt atgtagtatt tttcttttgg aaatgtgcct     4680

tatgttaaac actatgtact tttacttttt gcattgtcca gacttcttta ttagatggag     4740

atgtttcttt ttctgtcttc tagactaaat agagtatcat ccaaataatg gggcctatga     4800

cttgaatgaa tagaaatgaa taagctggtg tttgtttttt caaaatggaa gtaatttaga     4860

tttgttctcc tcatacataa aatgatttta gttcagtttt aaccagtgaa aactttgttt     4920

ttatgaaaaa aaaggaaaat ggtttcccat ttggttttat atgtgttaaa taaatgtgta     4980

aagtaaccac caaatgttat tagaattttt cttctagcat ttataatttt ttcaactcct     5040

attgtgtttc tttgtgtgtg atattttaat caaaagtggt tgagttgtta acagtgttct     5100

ttgaaagaat ctctaaaagg cttataaatg tttgaaatat cacacaaagg ctgatttcta     5160

aaatatatat atattaaaac aataaagtat ttattttgcc taaaaaaaaa aaaaaaaaaa     5220


<210>  1719
<211>  2891
<212>  DNA
<213>  homo sapiens

<400>  1719
aaaaaaagga aaaggaaaaa gcccatgaaa tgctactagc tacttcagac ctctttcagc       60

ctaagaggaa agcctgttag cagagcacgg accagtgtct ccggagaatg ctattctcct      120

acatttccga acaggttatc aacgcacaga tcgatcactg cctctgtccc atcgctccct      180

gaagtagctc tgactccggt tccttgaaag gggcgtgtac agaagtaaag atggagcctg      240

caggggagcg ctttcccgaa caaaggcaag tcctgattct ccttctttta ctggaagtga      300

ctctggcagg ctgggaaccc cgtcgctatt ctgtgatgga ggaaacagag agaggttctt      360

ttgtagccaa cctggccaat gacctagggc tgggagtggg ggagctagcc gagcggggag      420

cccgggtagt ttctgaggat aacgaacaag gcttgcagct tgatctgcag accgggcagt      480

tgatattaaa tgagaagctg gaccgggaga agctgtgtgg ccctactgag ccctgtataa      540

tgcatttcca agtgttactg aaaaaacctt tggaagtatt tcgagctgaa ctactagtga      600

cagacataaa cgatcattct cctgagtttc ctgaaagaga aatgaccctg aaaatcccag      660

aaactagctc ccttgggact gtgtttcctc tgaaaaaagc tcgggacttg gacgtgggca      720

gcaataatgt tcaaaactac aatatttctc ccaattctca tttccatgtt tccactcgca      780

cccgagggga tggcaggaaa tacccagagc tggtgctgga cacagaactg gatcgcgagg      840

agcaggccga gctcagatta accttgacag cggtggacgg tggctctcca ccccgatctg      900

gcaccgtcca gatcctcatc ttggtcttgg acgccaatga caatgccccg gagtttgtgc      960

aggcgctcta cgaggtgcag gtcccagaga acagcccagt aggctcccta gttgtcaagg     1020

tctctgctag ggatttagac actgggacaa atggagagat atcatactcc ctttattaca     1080

gctctcagga gatagacaaa ccttttgagc taagcagcct ttcaggagaa attcgactaa     1140

ttaaaaaact agattttgag acaatgtctt cgtatgatct agatatagag gcatctgatg     1200

gcgggggact ttctggaaaa tgctctgtct ctgttaaggt gctggatgtt aacgataact     1260

tcccggaact aagtatttca tcacttacca gccctattcc cgagaattct ccagagacag     1320

aagtggccct gtttaggatt agagaccgag actctgggga aaatggaaaa atgatttgct     1380

caattcagga tgatgttcct tttaagctaa aaccttctgt tgagaatttc tacaggctgg     1440

taacagaagg ggcgctggac agagagacca gagccgagta caacatcacc atcaccatca     1500

cagacttggg gactccaagg ctgaaaaccg agcagagcat aaccgtgctg gtgtcggacg     1560

tcaatgacaa cgcccccgcc ttcacccaaa cctcctacac cctgttcgtc cgcgagaaca     1620

acagccccgc cctgcacatc ggcagtgtca gcgccacaga cagagactcg ggcaccaacg     1680

cccaggtcac ctactcgctg ctgccgcccc gggacccgca cctgcccctc acctccctgg     1740

tctccattaa cacggacaac ggccacctgt tcgctctcca gtcgctggac tacgaggccc     1800

tgcaggcttt cgagttccgc gtgggcgcca cagaccgcgg cttcccggcg ctgagcagcg     1860

aggcgctggt gcgagtgctg gtgctggacg ccaacgacaa ctcgcccttc gtgctgtacc     1920

cgctgcagaa cggctccgcg ccctgcaccg agctggtgcc ccgggcggcc gagccgggct     1980

acctggtgac caaggtggtg gcggtggacg gcgactcggg ccagaacgcc tggctgtcgt     2040

accagctgct caaggccacg gagcccgggc tgttcggcgt gtgggcgcac aatggcgagg     2100

tgcgcaccgc caggctgctg agcgagcgcg acgtggccaa gcacaggcta gtggtgctgg     2160

tcaaggacaa tggcgagcct ccgcgctcgg ccaccgccac gctgcaagtg ctcctggtgg     2220

acggcttctc tcagccctac ctgccgctcc cagaggcggc cccggcccaa gcccaggccg     2280

actcgcttac cgtctacctg gtggtggcat tggcctcggt gtcttcgctc ttcctcttct     2340

cggtgttcct gttcgtggca gtgcggctgt gcaggaggag cagggcggcc tcagtgggtc     2400

gctgctcggt gcccgagggc ccctttccag ggcatctggt ggacgtgagc ggcaccggga     2460

ccctttccca gagctaccag tacgaggtgt gtctgacggg aggctctgaa agtaatgatt     2520

tcaagttctt gaagcctata ttcccaaata ttgtaagcca ggactctagg aggaaatcag     2580

aatttctaga ataatgtagg tatctgtagc tttccgaccg tctgttaatt ttgtcttcct     2640

cacttttcac cttagttttt tttaaccctt tagtaatctt gaattctact tttttttaaa     2700

tttctactgt tgtctttagt aatgttactc atttcctttg tctgattgtt agttttcaaa     2760

ttattgtatt attataaata ttttatatca ggaaagttca tatttctgaa taaattaata     2820

gtattcattc ctgaagggtg atatgaaagt taaccccacc taataaacat aactctaatt     2880

ctgaaaaaaa a                                                          2891


<210>  1720
<211>  9573
<212>  DNA
<213>  homo sapiens

<400>  1720
ggcgaccgcg gcggcgctct agctgcggca tgtctgcgtc tctactgctc tgggaggagg       60

aagagaagga ggaagaggag gaggaggagg agggggagga agaggagaaa ggcgcagggg      120

tgggagctgt tgccgaagct gccacagcaa aagttctccc ccctcccccc ttcccctcct      180

ctcaaggccc ctagaaaggt tggagctgcc gccgcctgca gtcggtgacc gcgcgactcg      240

gcgcccgccc gcggatagag ggaggaatca gcagcttgga aattcaagca cgtgatctgg      300

cgggatgggc gtttgcctaa cgtatttaat ggaggaatcg gatggcataa gtgattaagg      360

tggtattgag gatttctgaa gcctatgaaa ggtagaaact caaccatgat ttctttttca      420

actctacagc attcctttcc ttgaagtctt cgtttttacc ttagtctcgg gcagttatac      480

ttaagcatga acattgacga caaactggaa ggattgtttc ttaaatgtgg cggcatagac      540

gaaatgcagt cttccaggac aatggttgta atgggtggag tgtctggcca gtctactgtg      600

tctggagagc tacaggattc agtacttcaa gatcgaagta tgcctcacca ggagatcctt      660

gctgcagatg aagtgttaca agaaagtgaa atgagacaac aggatatgat atcacatgat      720

gaactcatgg tccatgagga gacagtgaaa aatgatgaag agcagatgga aacacatgaa      780

agacttcctc aaggactaca gtatgcactt aatgtcccta taagcgtaaa gcaggaaatt      840

acttttactg atgtatctga gcaactgatg agagacaaaa aacaaatcag agagccagta      900

gacttacaga aaaagaagaa gcggaaacaa cgttctcccg caaaaatcct tacaataaat      960

gaggatggat cacttggttt gaaaacccct aaatctcacg tttgtgagca ctgcaatgct     1020

gcctttagaa cgaactatca cttacagaga catgtcttca ttcatacagg tgaaaaacca     1080

tttcaatgta gtcaatgtga catgcgtttc atacagaagt acctgcttca gagacatgag     1140

aagattcata ctggtgaaaa accatttcgc tgtgatgaat gtggtatgag attcatacaa     1200

aaatatcata tggaaaggca taagagaact catagtggag aaaaacctta ccagtgtgaa     1260

tactgtttac agtatttttc cagaacagat cgtgtattga aacataaacg tatgtgccat     1320

gaaaatcatg acaaaaaact aaatagatgt gccatcaaag gtggccttct gacatctgag     1380

gaagattctg gcttttctac atcaccaaaa gacaactcac tgccaaaaaa gaaaaggcag     1440

aaaacggaga aaaaatcatc tggaatggac aaagagagtg ctttggacaa atctgacctg     1500

aaaaaagaca aaaatgatta cttgcctctt tattcttcaa gtactaaagt aaaagatgag     1560

tatatggttg cagaatatgc tgttgaaatg ccacattcgt cagttggggg ctcgcattta     1620

gaagatgcgt caggagaaat acacccacct aagttagttc tcaaaaaaat taatagtaag     1680

agaagtctga aacagccact ggagcaaaat caaacaattt cacctttatc cacatatgaa     1740

gagagcaaag tttcaaagta tgcttttgaa cttgtggata aacaggcttt actggactca     1800

gaaggcaatg ctgacattga tcaggttgat aatttgcagg aggggcccag taaacctgtg     1860

catagtagta ctaattatga tgatgccatg cagtttttga agaagaagcg gtatcttcaa     1920

gcagcaagta acaacagcag ggaatatgcg ctgaatgtgg gtaccatagc ttctcagcct     1980

tctgtaacac aagcagctgt ggcaagtgtc attgatgaaa gtaccacggc atccatatta     2040

gagtcacagg cactgaatgt ggagattaag agtaatcatg acaaaaatgt tattccagat     2100

gaggtactgc agactctgtt ggatcattat tcccacaaag ctaatggaca gcatgagata     2160

tccttcagtg ttgcagatac tgaagtgact tctagcatat caataaattc ttcagaagta     2220

ccagaggtca ccccgtcaga gaatgttgga tcaagctccc aagcatcctc atcagataaa     2280

gccaacatgt tgcaggaata ctccaagttt ctgcagcagg ctttggacag aactagccaa     2340

aatgatgcct atttgaatag cccgagcctt aactttgtga ctgataacca gaccctccca     2400

aatcagccag cattctcttc catagacaag caggtctatg ccaccatgcc catcaatagc     2460

tttcgatcag gaatgaattc tccactaaga acaactccag ataagtccca ctttggacta     2520

atagttggtg attcacagca ctcatttccc ttttcaggtg atgagacaaa ccatgcttct     2580

gccacatcaa cacaggactt tctggatcaa gtgacttctc agaagaaagc tgaggcccag     2640

cctgtccacc aagcttacca aatgagctcc tttgaacagc ccttccgtgc tccctatcat     2700

ggatcaagag ctggaatagc tactcaattt agcactgcca atggacaggt gaaccttcgg     2760

ggaccaggga caagtgctga attttcagaa tttcccttgg tgaatgtaaa tgataataga     2820

gctgggatga catcttcacc tgatgccaca actggccaga cttttggcta aaaaaaaaaa     2880

aaaagtgtaa ataatactgg cactttagaa cagattaatc aagagtgggg ttactctgtg     2940

taaatggagt gctgtacaga tttaagagca atgcgtaata acaagttaag ctgatatgaa     3000

tagcaagata atccaataac tgcatttcgt ttggttagtc agcattcttt gaactgcctt     3060

acatgttgtc acctttatag aagcaatgca ttacttgttt tagatcagaa acttgctatt     3120

ccacccacac caagttaaaa aggaaaaaaa aaagactttc gcacaattgt ttcctaactg     3180

ataacattgt acattcttag gagattagta attgtgtgaa atttactcat actgtttcta     3240

agtttttcag catagtcatt gcacttcagc agggaatctg agtatacttt acagacagag     3300

tgaacttaaa agtttaatgt caagagatta tggcttaaat aaattagtgt gtcctatagg     3360

gggaaaaaaa ccaagaaacc accttttaaa aagaatgata tgccatatac ccttgatttt     3420

cattttgcat tatattgacg tgtttttttg aaggaaaaaa agtaataaaa atctgatagt     3480

ctaagactcc actatttaaa agcctaatta ctttaaaaat atgcatactt tcagaacttt     3540

taccaaaaca cacaactgtt gaagcagtca cttctctatg gaagtatgca tattggtgtc     3600

agtttctttg tacagttgta cttagatatt ttttatgatt tttcatgtgc aggtatcaag     3660

gttttgaagt tttagtaaaa gaaattctgt agattacatt cccaagaaca taatgcttac     3720

acaaaatgta tattccacgt tttaaagctt aattgtattt tactttacat atacacttca     3780

gttaacatag agcacttaga atctatttgg tatttttgat ttctcaaagt aaaaaaaaaa     3840

ttagattttt aggtttgata tggttgtgtc ataatcatct cgtaattgac aattttaact     3900

tttggcaata aaaggaaatt gggatatctt tggaactgta aaacctggtt taatcttttt     3960

ctttctagac tcttgataga ttggataatt aaacagtatc cagagaaact aaagaaatgg     4020

gcattttaat tgcatatttt atcttgagtt actttttaat gaacactgct cattacaact     4080

ttacaaacca aaagtgttta ctaattccag taactaccat ttctttttca gctagatgag     4140

tgatcggaaa atttttgttg catttcaaaa tctaaataaa ctacagactt tatccttata     4200

ccatgaatgt ttttttttaa tactctgtct taaaataata cagcatggta caataaatag     4260

tgcttttatg tatatataca cacacacact tttctgaaga atgatggttt gagttatgcg     4320

ttgggcagtt ttgatttttg gaagttatat tagttattga ctctttgtta caactttttc     4380

atttttacat tttaaatttt ctgccatcgt tgtcacaatg cacatcctga tatagcacca     4440

gtgaaaatct aaaattaata cccttggaaa atgaaaatat tcttaatttc cattttgact     4500

cttatactgg ccctatagct ctgcagtctt tgtttcaata tagaatatgt tatccattta     4560

aattattttt tcttttattt aatgttatcc caagactgtt ctcataaaga aagggaagaa     4620

ataactatcc acccttaaca tccttcattt attttgaata tattggtgtt tttatgataa     4680

ggaatataaa ttatatttaa tgtggtttcc tgtatacttt ggttattaag ttttgcttga     4740

aatagtagtt ttcccgtttg acagctttct ttgctgccaa agttttcaag aatttaagac     4800

ttctttgaag taaatattta agttctgcca ttattgactc ttaagattgt gtgtgttgtg     4860

ttgtgcatta cataattaca aaaaggcttc attcaggtga tacgttaaaa atggaactgt     4920

gctcacccta aataggcatt ggtatttttc tcttttggtg agagtaggca tttatttctt     4980

gagttgtttt ggagcctgat caaaaatttt gttcatggag aacttgatgc aattttgata     5040

cagtggagag gtttttttcg gttgttttaa catcaccagc atagttttta gaatgtgact     5100

cttgctgagc atttagggtg agcttgggaa ggaaggcctt tgaaaatggt agttatgcaa     5160

gcagactttc aggtgttgca ttcctgtttt caacacattt ctttaaatct acataatggc     5220

agacttttct accaggttat aagcagtttt tagataagtg atactcagcc agcataactt     5280

attgacttac catttacgta tagtcatcac tctcttactg tgaaattcca aatgcctacc     5340

agagttacct tgttctatca taatatgaca aacatctcaa cagttttgga tttccccact     5400

ttggttcaga aggttattta atttctatct gggcattaat ggagaaaata agtagccttg     5460

tgtgctgctt cagattgaaa catggaggat atgagatatt cttctgcaat tcatgtttct     5520

catttctcaa agtgagcaca ttgttctata aaaacatgct ggtacaccct taaacttttg     5580

atcaatctga gtgaggtgtg cttttcctct tgggacctac tcacgtttga agattggaaa     5640

catcacgtta ggcgaggcag tatctcttga acatcttcta aagggttttt taaaacctta     5700

ttctcacata tttcatttgt cttgaatatt taagtggctc ttaaacgttt tgggtctaca     5760

tgcaaatgtg gtacttaaca aggtaggaat ccatcttctt agctctggct gagggtgcca     5820

gccatcggtc aggtcatttt tatctcaaga ggcagaaggc agttatgtca agaattgtgc     5880

tcagggcagg atttcgtttc cacagaggag agacacttgc agagtgccag ctaggttaga     5940

tcttttgccg cttctttcat ttgattaatt tgggttttta aagggctgtt taaaaaaaaa     6000

aaaaaaaggc cgggaaactt taaaagtagg cattactgta gtactgcatt tcttagaaca     6060

ttttaaacta gaactcattt ttttttcaca gtatatttac ttgaagaagc actataataa     6120

tcattgagaa gtattttgag tctgaaattt aatttaattt tccgtttcaa attgctttat     6180

ttcagggaaa taattttcca gttgttttgc tatattctgc aaataaaaac cgtgtttcct     6240

tttttcactt aaactttggt aggaaacaaa ctaaagcaga caaacatttc ttgttatgtt     6300

tgttgctttc tttaatccaa tggataaaaa agtaaaaccc tgtaaacatt attttatttt     6360

tttatgcaat accatgctgt aaatatggtt catcaaataa ggatgtacct atgattgaat     6420

ctttaattct gcacagttag agtttatata taaacgtgtc ttgacaatca aggactttta     6480

tgtgagtctt cctttatgat gtttattaat gttatgcatt ccatttgttt tgaagtgagt     6540

accaatgtgc taatttgtat tgtctgaaag tatgtaatgt ttttacagct tgtttttaag     6600

aatctgtaaa tatgtacaaa caaatcacag tactgcttta tgttagaagg catatgatgt     6660

tgtactgtat gtaagcaata atacatagca gtgctaactt tacaagtagc atcaggaaag     6720

ttctaaaaac atttcagagt tattaattat ccttatttca tttaataatg attatcttta     6780

atcagttttt ataagcaaat tccattgttc ctcctattgg aacgtaacac tgtttacaca     6840

gcataattga agttgcaggg gagacaggct aaatctgact tcatctgtac tcactttcac     6900

taagcattga atggccttac cactcttctg caagatggag gaagaccgca aaacttagtg     6960

cccatcacac tgaaggaagg gatgtggttt tttttcctgc ttctgtactg ctacctaact     7020

ttgtgatttg ctttggattt taatatttgt ttctgtttta gattcaagcc cgtaagtttt     7080

gaggtgactt cagctccatt gtgaaataga tagttctctt catatttcat aactacattt     7140

caataattct aaactttcta cattgatttt tagatactta tttttcaagc ttggtttctc     7200

agctgatcag atgaatttat tcaacttcaa tacaaagaaa gacaaaccta ttatagtttc     7260

aagtgagtag atattatact gtacaggaca gctatttgaa cacacacatc actgctttag     7320

aaataaaacc gccaatttat aaatgtatat gacctacatt ttataggaaa aaatgttttt     7380

aaatgctagt catttatata atgtgctttg aaggatttgc tagtccactt ctgtcacttt     7440

ttagtacact ggtatctttt atatgtaatg tatgcttttt attattgtag caaagcattt     7500

cagtagaaag aattttgcaa caatatgggg gaaatttttc attgttggat ttgaattata     7560

ctggatttta tctgtgtagt cttacttgtc tttattttaa tgctgtctga agggaacttg     7620

gtatccaaat aaagcaggta acctcatttt acttcaaggg catactgtgt agtgctgaat     7680

ttaatctgaa aatctgatga ttttgaaaag aaaaacaagt ttataaacat tgtacagaag     7740

aaattaaatg tgtgtgatgg aaatcctgat ggtggagcac gttgaatttt ctgatatata     7800

gtgttatttt cctgggatcc cctatgcctt ctttgtattt caactaataa aggaaaaacc     7860

ctgtcattaa aactggtaag ataataggat attctgatta tacagtatta ctattcctat     7920

cccattttct gaccttttct caatcactgt aaatttttat tttctatttc ctattgataa     7980

ttaaatatgt acataatata gacactgttg tatagaacta aatgaattgg gttgctatgc     8040

ttgagtgggt agtgaaatgg aaatatttga tgaatactga gagttcctaa aatgctagag     8100

caaatttccg agggaaaggg gggcatcgtg tgtcttggga aggttgcagc aggttgtttc     8160

ttcaactccc taagaaatca ttgggaagga ctcaactgca aactcgggat cagatacaaa     8220

atgggtcttt ccttcccctc tcccccaaaa aataggagca ctaaatttta aaatctactc     8280

aggtgacagt tgctttgcaa tgaaacttat cacattgaaa ttttcagtgt taaataaaaa     8340

gagatttgtg atatttttaa atataaactt ttacatcagt agtcagcagc ctgacaattg     8400

aaatttggta agtcgatata ttttaaaata ttttgctctc caaatagaat tgtttttaaa     8460

caattgggag gttttttgtt tctttaaata tgttttaatt gtcattgtaa aaacaaaatc     8520

ttgcttgacc ctatattatg ccatgaatga attgctgagc ctttataata cagtgacagc     8580

ttgtttcatg catagtcatg gaacatagag atgttcttta aactgaccta ttgataagag     8640

gtttaatgag tttcacggct ttcaacacta ttgtcatata gttatctttg ccatttggag     8700

tttataaaac cattttatgt attgtgatac taaaggaagt tgttttgctt tactttaaat     8760

tgaattatta gactaatatt tgcaaattct gcattttaaa tgtggacact ggctgtttga     8820

aaaataaaat atagaataca gttttatgga taattttcga gctgaatttt tcacaatatt     8880

ctgaaccaaa taacgaatgg taaatatgca aaaatcatgg tgcatagata taaccgtaaa     8940

gagaaaagaa tttctgtgtg gaattaacag ttacacaaat tgggtaacaa ttatcagggc     9000

ctttattata gctttatgtg gaatgttatt ctaaaatgca agagtcaaat gttactgtca     9060

ttgaatattt tagacttgaa acgtgtttat catagagcga agaaaatatg tgttcttttc     9120

tttacagata agactctgtt aacccactgt cagcatacgt gggatttctt ttcttttttc     9180

tttcattagt ggagatttgt tttcatccat ctaccacctt gccagtaccc tagcttgtga     9240

ccagcgggat gcattgtaag aaagttgtct gtggttagga gtgcagtctg ggtccatgga     9300

acaaatttaa actaattggc cctcgcaatg atcagtccta ggaccctggc cttattatta     9360

gcatggtgct ttaaccaatt gtacataata ataccactga tagtctacta atgcatttcc     9420

tagatcccag tttttcttga atgattagga atggtgggga gaggggaggg gagatattct     9480

acatgatact tctccaatct tctaaagatt ataagaaaaa ataaaaaatt gaagtcactt     9540

gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa                                  9573


<210>  1721
<211>  6015
<212>  DNA
<213>  homo sapiens

<400>  1721
gtctggtgag gaaatcatca ccctaggacg taaaccctcc cgcccttctt tcagctctta       60

aaaaaagcct gccacgaaag tccctactgc gttgctgcga acgtagcttt gagaagctgg      120

cgcccagtga tggggcaaac agccatgccc ttccagcagc cgtgaaagcc ccaacagcaa      180

actgcctggg agcggggcag gtcaccaact tcgttgctcg aactccctgg gtgcccgccg      240

cggtggttac aaagggggtc aagagtgccg gacccagccg cgcggagccc accattgcgg      300

cccgaggggg acccgacggg ggcccgacgg tgtggcgtgg cgcaaggagc gcgcctgcct      360

tctctcgccg ccgggaacgg gctgcaccaa tggccagatt ccagcaagat tatggaagag      420

catagctaca tacaaaagga gctagattta caaaatggta gcttagagga agactctgtg      480

gtgcattctg ttgagaacga ttcccaaaac atgatggaga gcctcagccc aaagaaatac      540

tcttccagtc tgagatttaa agccaatgga gactattctg gctcctattt aaccctctca      600

caacctgtgc ctgcaaagag aagcccttct cctttgggaa ccagtgtcag aagcagcccc      660

tccttagcca aaatccaggg aagcaagcag ttctcttatg atggaactga caaaaatatt      720

cctatgaaac ctccaactcc tttactcaac actacatcct ccctcagtgg atatccactt      780

ggaagagcag actttgatca ttatactggc cgggacagtg aaagggcctt gaggctctca      840

gagaagcctc cctattccaa atatagctca aggcataaat cgcatgacaa tgtctactct      900

cttggagggc tggaaggtcg gaaggcatct ggctcgctcc tggccatgtg gaatggaagt      960

tccctgagtg atgctggccc gcctcctatc agcagatcgg gagccgcaag catgccttca     1020

agcccaaagc aagccaggaa aatgagcatt caggacagcc tggcgcttca acccaagtta     1080

actagacaca aggagcttgc atctgaaaac atcaatttga gaactaggaa gtactccagc     1140

agcagcctga gtcacatggg agcctacagc cgatcacttc ccaggttgta cagagccaca     1200

gagaaccagc tgacacctct cagcttgcct ccaagaaact ctctgggcaa ttccaaacga     1260

acaaaacttg gggaaaagga tctacctcat agcgtaatag acaatgacaa ttaccttaat     1320

ttttcttctt tgagctcagg ggctttaccc tataaaacct ctgcttctga aggcaatcct     1380

tatgtaagtt ctaccctcag tgtccctgcc agtccacgag tggctcggaa gatgcttctg     1440

gcctccacct cctcctgtgc ctctgatgac tttgatcagg cttcatatgt ggggacaaac     1500

ccgagtcatt cacttcttgc tggagagtca gacagagttt ttgcgaccag gaggaacttc     1560

tcttgtggat ctgtggaatt tgatgaggca gatttggaaa gcctcagaca ggcctcagga     1620

accccccagc ctgcccttcg ggaacggaaa agcagtatta gctccatttc aggacgtgat     1680

gacctgatgg attatcaccg gcggcagagg gaggaaagac tcagggagca ggaaatggag     1740

cgattggaga gacagcgtct ggagaccatc ctcagtctct gtgctgaata cacaaagcct     1800

gacagtcgct tatctactgg gaccaccgtg gaagatgtgc agaaaatcaa caaggagctt     1860

gagaagctgc agctctctga tgaggagtct gtgtttgagg aagccctcat gagccctgac     1920

acaagataca ggtgccaccg gaaagactcc ctccctgatg cagacttggc aagctgtggg     1980

agtctcagtc agagcagtgc cagcttcttt acccccagga gcaccaggaa tgatgaacta     2040

ctcagtgacc tcacccggac tcctccacca ccatcctcca cctttccgaa agcttccagc     2100

gagtcctctt atctaagtat cctaccaaag accccagagg gtataagtga agaacagaga     2160

tctcaggagt tggctgcaat ggaagaaacc cggatagtca ttctgaacaa cctcgaggaa     2220

cttaagcaaa aaatcaaaga cataaatgat cagatggatg agtctttcag agagttggat     2280

atggaatgtg ctcttttgga tggagaacag aaatctgaaa caactgaact tatgaaggag     2340

aaggagattt tggatcatct aaaccggaaa atagctgaac tggaaaagaa cattgttggt     2400

gaaaagacca aggatgctga cctgttggat gttgaaagca aacactttga agacctggag     2460

ttccagcagc ttgaacatga gagccgtcta gatgaagaaa aggagaactt gactcaacag     2520

ctcctgcgtg aagttgctga atatcaacgg aacatcgttt ctagaaagga aaaaatttct     2580

gcattgaaaa agcaagccaa tcacattgtt cagcaggctc agagagagca agatcatttt     2640

gtgaaagaaa agaataattt aataatgatg ttgcaaagag aaaaggagaa tctttgtaat     2700

ttggaaaaga aatactccag cctctctggg gggaaagggt ttcccgttaa ccccaatact     2760

ttaaaagagg gctatatcag tgtaaatgag attaatgagc cgtgtggcaa ttccacgaat     2820

ctatcccctt ccactcagtt tcctgctgat gctgatgctg ttgccactga gcctgccaca     2880

gctgtgctgg cgagccagcc acagagtaaa gagcacttta gaagtctgga agaaaggaaa     2940

aaacagcata aagaaggcct ctatctgagt gatactttgc ctcgaaagaa aaccacatct     3000

tccatctccc cacatttcag cagtgctact atggggagaa gcatcacccc aaaggcccat     3060

ctgcccctag gacagagtaa cagctgtgga agtgtgctcc ctccctcact ggcagccatg     3120

gccaaagact cagaatctcg gaggatgctc agaggttata atcaccaaca gatgagtgaa     3180

ggacacaggc agaaatctga attttataac cgcacagcat ctgaatcaaa tgtctacttg     3240

aatagtttcc attatccaga tcacagctac aaggaccagg cctttgatac tctgagcctc     3300

gatagctctg atagcatgga gaccagcatc tctgcttgct caccagacaa catctctagt     3360

gccagcactt caaatattgc tagaatagaa gaaatggaga gacttttgaa gcaggctcat     3420

gcagaaaaga cgcggctgct cgaatccagg gaacgggaaa tggaagccaa aaaacgagcc     3480

ctggaagaag aaaaacgacg ccgggaaatc ctggaaaaac gattacagga agaaactagc     3540

cagaggcaga agttaataga aaaggaagta aaaataaggg agagacaaag ggcacaggct     3600

cgtcctttga cacgctacct gcctgtccgg aaggaagact ttgatttgcg gagccatgta     3660

gagactgctg gccacaatat tgacacctgt taccatgtat caatcacaga gaagacctgc     3720

cgaggattcc tcatcaaaat gggtgggaaa attaaaacgt ggaaaaaacg ttggtttgtt     3780

tttgatcgga acaagcgaac attctcttat tatgcagaca agcatgaaac taaattgaaa     3840

ggagtaatat actttcaagc cattgaagaa gtctattatg atcacctcaa gaatgctaat     3900

aagagtccta atccgttact cacctttagc gtcaagactc atgacagaat ctattatatg     3960

gtagccccat cgccagaagc catgcggatc tggatggatg ttatagttac gggggcagaa     4020

ggttacactc acttcttgtt gtagtgaact gaggcaacag tccacttcag ggcagacggc     4080

aataatctct tacaagaatg aagccatatt caaccccaga tgagaaaacc caacagatcc     4140

atcccttgag ctgtaaacac tcagaactcc tttcatatca agacaagtta tttgtaaaaa     4200

ataaagaagg ggttttaata caaaccttca taataaatag caaaataatt gaagcttcca     4260

tgagaaagaa aacactattt tgataaattg gatcacttat aggaacattt ctaataaact     4320

gtttttaatc agttgtcgga tttggtgaaa taaactaaac aggttacaga atatctgtat     4380

gtacttggaa atacagaata actttatcac ccaaatcact ggcattgaca ttattggtaa     4440

tcaactggct ttttttaaaa aaggtagcat tttgttgaca gttattttgt aaacataagc     4500

aaataagggc ttggagggaa atacatttta ggaggagttt tgccttaatt ttttaagtac     4560

tgcaccaaaa ccaaagagct gacctgactt ctgtggaaca gtagtaactg caagtgatga     4620

actgcatttc gtattgttct gtatatttca aaatggtatt ttgatgccat caaatgccca     4680

ggaaattgac tttgcagtgt caccactggt gtaagctact atatatgtat atatatatgt     4740

agtaaaccac tttttgtaaa agaagaaaga gcaaaaagct gtgtgtttta gaaaaaaaag     4800

ccaggttacg caacaggcat tctgtcatgt tgaacaattt taaataaaga gaatatctgg     4860

tgttaggagc ttgttttgct gaagatttct ccattcctgg tgctgagaat aaaggcaacc     4920

agtagccaat gtcctttaga ttgtctgatt tctttttgtt gtggagcaca cctgctaact     4980

gctccctcaa cataactatg aaatcatagc tctgttttca ccaaagaaca gaccaattaa     5040

catacttatt tgcagaagtg gtgtagttct ataaaacggc aaatgaagtt caacttaata     5100

ttctctataa tgtattattt tattttattt tttacaatta gccttttttt tagttaattt     5160

ttgtcaaatg aaacgacttc aggcaagtct cttttataat ggtttttcaa gtgccattta     5220

ttctagttta tcatgttttg catgtttgaa agtatgaatg tgctctttcc taaaacatgg     5280

caaatgaata gatgtagaga ataacaatat tacttacaag atgaaatgat tagattagaa     5340

gtgtcccttt attaaacttt gtcagcctga ctgggtacaa ttcttttgtt aatttgcagt     5400

gtggtttgta tacacgtata cgtgttatca ataataagat tttgcaactg gatgacacaa     5460

gattttactt gaacagtgaa ggacaaaaat catgattgtg gaagatattt ttaaaatctg     5520

attttgcagc gatcactttt aaaccctgta gtgatgtaag actaaaatat aattgctaag     5580

attttgttgg ttaatgtaaa gatatgactt ttctgcactg tactctcttc ataggattgt     5640

aaaggtgttc taatccaatt gcatgatgta gtaagcctct taaatatgtg tgttaaatat     5700

attgagtttg gattaaaatg ttgacatgat ttcacatttg aaaataaact catctcttat     5760

tttgaagtta cctatctgta gtatgatgga ggatgaatta atcgcaaatg acagttgtag     5820

aaactatgta aagtttgttg tgtgctaaca ttatgatttg tagtgtataa actgaagtat     5880

tccaatagaa gtatctctgg ttacatccta ttgcttacaa aatgaaatga accctgaaaa     5940

actctgacat catattgttg tctgtttaca cagatacatt tattgctggg gattgcaaaa     6000

aaaaaaaaaa aaaaa                                                      6015


<210>  1722
<211>  2811
<212>  DNA
<213>  homo sapiens

<400>  1722
ccatttcaat agtcgcggga tacttgaact gcaagaacag ccgccgctcc ggcgggctgc       60

tcgctgcatc tctgggcgtc tttggctcgc cacgctgggc agtgcctgcc tgcgcctttc      120

gcaacctcct cggccctgcg tggtctcgag ctgggtgagc gagcgggcgg gctggtaggc      180

tggcctgggc tgcgaccggc ggctacgact attctttggc cgggtcggtg cgagtggtcg      240

gctgggcaga gtgcacgctg cttggcgccg caggctgatc ccgccgtcca ctcccgggag      300

cagtgatgtt gggcaactct gcgccggggc ctgcgacccg cgaggcgggc tcggcgctgc      360

tagcattgca gcagacggcg ctccaagagg accaggagaa tatcaacccg gaaaaggcag      420

cgcccgtcca acaaccgcgg acccgggccg cgctggcggt actgaagtcc gggaacccgc      480

ggggtctagc gcagcagcag aggccgaaga cgagacgggt tgcacccctt aaggatcttc      540

ctgtaaatga tgagcatgtc accgttcctc cttggaaagc aaacagtaaa cagcctgcgt      600

tcaccattca tgtggatgaa gcagaaaaag aagctcagaa gaagccagct gaatctcaaa      660

aaatagagcg tgaagatgcc ctggctttta attcagccat tagtttacct ggacccagaa      720

aaccattggt ccctcttgat tatccaatgg atggtagttt tgagtcacca catactatgg      780

acatgtcaat tgtattagaa gatgaaaagc cagtgagtgt taatgaagta ccagactacc      840

atgaggatat tcacacatac cttagggaaa tggaggttaa atgtaaacct aaagtgggtt      900

acatgaagaa acagccagac atcactaaca gtatgagagc tatcctcgtg gactggttag      960

ttgaagtagg agaagaatat aaactacaga atgagaccct gcatttggct gtgaactaca     1020

ttgataggtt cctgtcttcc atgtcagtgc tgagaggaaa acttcagctt gtgggcactg     1080

ctgctatgct gttagcctca aagtttgaag aaatataccc cccagaagta gcagagtttg     1140

tgtacattac agatgatacc tacaccaaga aacaagttct gagaatggag catctagttt     1200

tgaaagtcct tacttttgac ttagctgctc caacagtaaa tcagtttctt acccaatact     1260

ttctgcatca gcagcctgca aactgcaaag ttgaaagttt agcaatgttt ttgggagaat     1320

taagtttgat agatgctgac ccatacctca agtatttgcc atcagttatt gctggagctg     1380

cctttcattt agcactctac acagtcacgg gacaaagctg gcctgaatca ttaatacgaa     1440

agactggata taccctggaa agtcttaagc cttgtctcat ggaccttcac cagacctacc     1500

tcaaagcacc acagcatgca caacagtcaa taagagaaaa gtacaaaaat tcaaagtatc     1560

atggtgtttc tctcctcaac ccaccagaga cactaaatct gtaacaatga aagactgcct     1620

ttgttttcta agatgtaaat cactcaaagt atatggtgta cagtttttaa cttaggtttt     1680

aattttacaa tcatttctga atacagaagt tgtggccaag tacaaattat ggtatctatt     1740

actttttaaa tggttttaat ttgtatatct tttgtatatg tatctgtctt agatatttgg     1800

ctaattttaa gtggttttgt taaagtatta atgatgccag ctgtcaggat aataaattga     1860

tttggaaaac tttgcaagtc aaatttaact tcttcaggat tttgcttagt aaagaagttt     1920

acttggttta ctatataatg ggaagtgaaa agccttcctc taaaattaaa gtaggtttag     1980

gaaaacagac cctcaaattc tgacattcat tttcctaagc aactggatca atttgctgac     2040

ttgggcataa tctaatctaa gcatatctga atacagtatt cagagataga tacagtagag     2100

attccccaga ctttttcgct ctttgtaaaa cctgtttgtt taggttttgc gaggtaaact     2160

caacagaggt tgggagtgga agagggtggg aagcttatat gcaaattaac agacgagaaa     2220

tgctccagaa ggtttattat tttaaagcac attaaaaaca aaaaactatt tttaaaatcc     2280

tgctagattt tataatggat ttgtgaataa aaaataccca gggttctcag aatggaataa     2340

atatcccttt taatagttat atatacagat atacaactgt tagctttaat tggcagctct     2400

cttctttttt cttcttttca ctggcttttt acttggtgct ttttcttgtt ttgcactggt     2460

ggtctgtgtt ctgtgaataa agcaaagtaa gaatttacta agagtatgtt aagttttgga     2520

ttattgaaat aagaggcatt tcttagtttt ccagtaggat ctaaaatgtg tcagctatga     2580

gtaagactgg catccaagaa gtttatatta tagatttagg tcctaatttt tataaatcac     2640

aaggtaaaaa aatcacagaa cagatggatc tctaatgaaa aagggatgtc tttttgttta     2700

tagtcatgtg gcaagatgag agtaaaacca gagagcaaac ctctataagt gttgagtata     2760

tgtatacatt tgaaataaac cagaaatttg ttaccttaaa aaaaaaaaaa a              2811


<210>  1723
<211>  2177
<212>  DNA
<213>  homo sapiens

<400>  1723
cgaacgcctt cgcgcgatcg ccctggaaac gcattctctg cgaccggcag ccgccaatgg       60

gaagggagtg agtgccacga acaggccaat aaggagggag cagtgcgggg tttaaatctg      120

aggctaggct ggctcttctc ggcgtgctgc ggcggaacgg ctgttggttt ctgctgggtg      180

taggtccttg gctggtcggg cctccggtgt tctgcttctc cccgctgagc tgctgcctgg      240

tgaagaggaa gccatggcgc tccgagtcac caggaactcg aaaattaatg ctgaaaataa      300

ggcgaagatc aacatggcag gcgcaaagcg cgttcctacg gcccctgctg caacctccaa      360

gcccggactg aggccaagaa cagctcttgg ggacattggt aacaaagtca gtgaacaact      420

gcaggccaaa atgcctatga agaaggaagc aaaaccttca gctactggaa aagtcattga      480

taaaaaacta ccaaaacctc ttgaaaaggt acctatgctg gtgccagtgc cagtgtctga      540

gccagtgcca gagccagaac ctgagccaga acctgagcct gttaaagaag aaaaactttc      600

gcctgagcct attttggttg atactgcctc tccaagccca atggaaacat ctggatgtgc      660

ccctgcagaa gaagacctgt gtcaggcttt ctctgatgta attcttgcag taaatgatgt      720

ggatgcagaa gatggagctg atccaaacct ttgtagtgaa tatgtgaaag atatttatgc      780

ttatctgaga caacttgagg aagagcaagc agtcagacca aaatacctac tgggtcggga      840

agtcactgga aacatgagag ccatcctaat tgactggcta gtacaggttc aaatgaaatt      900

caggttgttg caggagacca tgtacatgac tgtctccatt attgatcggt tcatgcagaa      960

taattgtgtg cccaagaaga tgctgcagct ggttggtgtc actgccatgt ttattgcaag     1020

caaatatgaa gaaatgtacc ctccagaaat tggtgacttt gcttttgtga ctgacaacac     1080

ttatactaag caccaaatca gacagatgga aatgaagatt ctaagagctt taaactttgg     1140

tctgggtcgg cctctacctt tgcacttcct tcggagagca tctaagattg gagaggttga     1200

tgtcgagcaa catactttgg ccaaatacct gatggaacta actatgttgg actatgacat     1260

ggtgcacttt cctccttctc aaattgcagc aggagctttt tgcttagcac tgaaaattct     1320

ggataatggt gaatggacac caactctaca acattacctg tcatatactg aagaatctct     1380

tcttccagtt atgcagcacc tggctaagaa tgtagtcatg gtaaatcaag gacttacaaa     1440

gcacatgact gtcaagaaca agtatgccac atcgaagcat gctaagatca gcactctacc     1500

acagctgaat tctgcactag ttcaagattt agccaaggct gtggcaaagg tgtaacttgt     1560

aaacttgagt tggagtacta tatttacaaa taaaattggc accatgtgcc atctgtacat     1620

attactgttg catttacttt taataaagct tgtggcccct tttacttttt tatagcttaa     1680

ctaatttgaa tgtggttact tcctactgta gggtagcgga aaagttgtct taaaaggtat     1740

ggtggggata tttttaaaaa ctccttttgg tttacctggg gatccaattg atgtatatgt     1800

ttatatactg ggttcttgtt ttatatacct ggcttttact ttattaatat gagttactga     1860

aggtgatgga ggtatttgaa aattttactt ccataggaca tactgcatgt aagccaagtc     1920

atggagaatc tgctgcatag ctctatttta aagtaaaagt ctaccaccga atccctagtc     1980

cccctgtttt ctgtttcttc ttgtgattgc tgccataatt ctaagttatt tacttttacc     2040

actatttaag ttatcaactt tagctagtat cttcaaactt tcactttgaa aaatgagaat     2100

tttatattct aagccagttt tcattttggt tttgtgtttt ggttaataaa acaatactca     2160

aatacaaaaa aaaaaaa                                                    2177


<210>  1724
<211>  5825
<212>  DNA
<213>  homo sapiens

<400>  1724
atcgcctggg taggtttcca gggaaggcag cgagcaggat cccctactct gcgggcggcg       60

cgaggcgtct ggctcttcgc ggcggcggcg aggggaaagg gagcgcgggg gctgggtgga      120

atcgaggagt gaggaaaaag ggaaggggcg ggggagaggg accagggaag gcgtcggggg      180

gaatctcgcg agggttggag ttttggcgag agtttgtgga agatggcgcc tgttgtgaca      240

gggaaatttg gtgagcggcc tccacctaaa cgacttacta gggaagctat gcgaaattat      300

ttaaaagagc gaggggatca aacagtactt attcttcatg caaaagttgc acagaagtca      360

tatggaaatg aaaaaaggtt tttttgccca cctccttgtg tatatcttat gggcagtgga      420

tggaagaaaa aaaaagaaca aatggaacgc gatggttgtt ctgaacaaga gtctcaaccg      480

tgtgcattta ttgggatagg aaatagtgac caagaaatgc agcagctaaa cttggaagga      540

aagaactatt gcacagccaa aacattgtat atatctgact cagacaagcg aaagcacttc      600

atgttgtctg taaagatgtt ctatggcaac agtgatgaca ttggtgtgtt cctcagcaag      660

cggataaaag tcatctccaa accttccaaa aagaagcagt cattgaaaaa tgctgactta      720

tgcattgcct caggaacaaa ggtggctctg tttaatcgac tacgatccca gacagttagt      780

accagatact tgcatgtaga aggaggtaat tttcatgcca gttcacagca gtggggagcc      840

ttttttattc atctcttgga tgatgatgaa tcagaaggag aagaattcac agtccgagat      900

ggctacatcc attatggaca aacagtcaaa cttgtgtgct cagttactgg catggcactc      960

ccaagattga taattaggaa agttgataag cagaccgcat tattggatgc agatgatcct     1020

gtgtcacaac tccataaatg tgcattttac cttaaggata cagaaagaat gtatttgtgc     1080

ctttctcaag aaagaataat tcaatttcag gccactccat gtccaaaaga accaaataaa     1140

gagatgataa atgatggcgc ttcctggaca atcattagca cagataaggc agagtataca     1200

ttttatgagg gaatgggccc tgtccttgcc ccagtcactc ctgtgcctgt ggtagagagc     1260

cttcagttga atggcggtgg ggacgtagca atgcttgaac ttacaggaca gaatttcact     1320

ccaaatttac gagtgtggtt tggggatgta gaagctgaaa ctatgtacag gtgtggagag     1380

agtatgctct gtgtcgtccc agacatttct gcattccgag aaggttggag atgggtccgg     1440

caaccagtcc aggttccagt aactttggtc cgaaatgatg gaatcattta ttccaccagc     1500

cttaccttta cctacacacc agaaccaggg ccgcggccac attgcagtgc agcaggagca     1560

atccttcgag ccaattcaag ccaggtgccc cctaacgaat caaacacaaa cagcgaggga     1620

agttacacaa acgccagcac aaattcaacc agtgtcacat catctacagc cacagtggta     1680

tcctaactac cgtctttttg ctaggactta aactgacttg agtgtggcaa aaagttaaca     1740

aaaaaggaga aaaaatgaac aatcgtttgt ggtttcttgg gaaaactttt cataccaggt     1800

gatactattc aaaaaccccg ttgtctccct gcaagtgctg atttgaaatg cagaagccac     1860

agtaaaaaaa aaaaaaaaaa aaaaaaaaaa gaaaaaaaaa tcaaaatgta taaatattgg     1920

aaatcaagtt tttcagctgt tttgttggtt ggttggttgg tttttgtttg gttttgttta     1980

aatgggcaag aagtaaataa tgtggctgga atacaagttg aacaaactag aagacacaaa     2040

tctaacatag tttttatgga ccaaggaact tgtatattgt ataagcttta gtaaaaggta     2100

cattttcacc ataccttttt ttatatcacg gtattatagt acaccttgtt accaaatagg     2160

ttgttctctt ccccacccac ctttgagctt ttgctctaaa atacattcag gttccaagcc     2220

tgaccatcct tgtttaatct atcatactct tccaggtttt ttttttttgg tctaaggctg     2280

gaactttttt cttttttttc agctgaagtc ttatgacttt tcatgagtca aaattgtttg     2340

gatttcagca agtcaaatct tgcaaaggcc tgcatatttt ttttaagatt atatgaagtc     2400

tgtgcaaaag ctttaaaaaa atgcctctgc cttgcctgca atacatgcaa tgtatgttaa     2460

cttagtctct cttctcagac actgttggta gttatttctg tgttttcctt tttttaaaaa     2520

aaaatatgga cttattgtgg ttatctgaga ggttctaaca ttcacatgca atttggtgtg     2580

gccatttagc tattaatgag ttaatggcgc agaacttgtt gatatttgaa gtgttctctc     2640

cccttttccc atgacgtaaa tacataggtg tgttccagga tttgttcagg tttttccccc     2700

ctcctaatct tgtacataac ttgtattatg tgtaagttaa acattttatt ttgaacttgg     2760

aatgttccca gtgatttcat tcagcagggt attttctgcc ttgttggcaa gtgacaaaaa     2820

atatgggaag tatttgctac cagttggtag atggtgccct taatggtaga atgaggaaaa     2880

tgtccgcaaa agcatgtttt attatcttta cttttttggg gggttggagg gggtagccta     2940

gccagaacat cattgtaatc ttaaaacata agatgctttt attagatgat caactaaaat     3000

agctggaaga cagtacttta gaaacagata gttgtaagat tataaaatgc aaatgtaact     3060

tatgttttca tttttttctc tgcctttttt gtttgtttgt tttctctttt ccagtactga     3120

gcatctccac aaatgtctcc taactcagaa aatgtttctt ttcttttcag ttgagatttg     3180

gttgcattca gggttgtagg ttggccttgc ttgctaaccc cgccggtttt accgtgcttt     3240

cattcctgaa ctttgtttat gcctttgttt ggtttcttcg aaattgcagc agactcattg     3300

ggctacattt agtacaggaa ccacgtgtgt aatgttatac aacacagtct agtaatacaa     3360

tcatccctct tagagtaaaa actacctcta gattgtggta agcttttact gtcccataaa     3420

acaggagcca cagtacctta tgaatgcaaa actgtaactt cctacagtgt ttccctacag     3480

aacattgtct ttctggtgtc ctgggctgtt ttgaaaaagt ttccattaat agacttttta     3540

gaaattatta ttagtagcat tttttttcca gctttgctgt cttcatcact cactctatgc     3600

tcagactatg ccactgtaaa tattcttcct aacatcttta aatcgccttt tcctcagttt     3660

tcaaggggaa ggtcatttgt aaagcacgtt aggtggttaa atcagttatt gcggttttct     3720

cttactgcaa gcctttttaa tcacccccag gctgcatttt attctatatc gccttttttc     3780

ttcaaatctg ctccaatcac tcacttctct cttataagct aatcctgcct cacaccttaa     3840

atctgtttca gtgatcaagg gcagaactca ttgtggcctt atctttcttt gttgtaattg     3900

ttcactgtct ctttcttaca gaccacttat ttctgagtag tagttattcc tctctatgga     3960

gtcatggcag gaatcattac acagtgcttt tgttcagagc atggacatgt tcctagtgct     4020

gctttgcttt aacggccaca agtttcctcc acttcctagg tttggtattt agttaaggaa     4080

tcatattaaa ttaaccaata acaaaagaga tacttttgaa gaacaaacta ttccttaccc     4140

atttttgtag ctcaaaaata atttttcaag ttcatgacct tattaaaatg aacttgtgtt     4200

tttttaacaa acatgtatgt tttattttga tagtttcttt ccgtaagata attgaaatat     4260

tatactgtaa acccttttct tttctttttt tgaaaagtcc aagaatgtac ttatacaggc     4320

atttttcccc acctattttt ggccattctc ataccacaga ctaaagagtg aaatgatttg     4380

tccattgtag cttattgttt atcagtagtt cttttgtcag ctgcttacat tttttctttc     4440

atggttttgt gaatcatttt cagtatgtaa tttataggaa ccttgtcctc tggttatagt     4500

agactgtgtg ccctcctcca gtgatggcat tattagacat gctggtcatt taccctcaga     4560

aagactctct tattagaatg gtgagtgctt cagttatagt atgtttgaat ttttaaaaaa     4620

ttctgtttta gaaatgtatc ttatgctctc atgactatgc agtttctaaa catacacata     4680

gaagctgagt ctctgatcca atatgttttt atttgttcca tttaatttat cacatagatt     4740

gggaaggcaa gctaaaagcc ttaaaaatgc cctttatatt ttgagtgatt tcagcgttga     4800

acactagtat actatctaaa tttgctgctc actttcttta aactgtggca attaaaggca     4860

tgtttataca tgacttaatc gtgaaatgtt tgtcactctt actgcacaga cttatctgca     4920

atcataactg gttagttttt ttgttttgtt ttgttttatt gtttttaatg aaactggtac     4980

catctgtgct ttcacaaaaa acttccaatg ccatttttga gaactaacct aactagtcat     5040

gctaaccaga aaatccactg gggaggaggt tccttttgaa acaaaatgct gttcagttag     5100

taaccaagtt actttgattg caaaagcagc tgtgtttctg ataagtactg aacaaatgtg     5160

tgtaattttc tgtgccagac ttatgacttt gttttcaagc actgtaatgt gggatggatg     5220

gttagaaaca ataatatatt agggtttctg tttaaccctt tcaggactga actgtatctc     5280

cttttgttaa ttttcccctg tgttgtgata aatgtttgcc agcattcagt actgtgttgg     5340

tccagatgta ggtttatatg ctcattttta gcttatttct tgtaccttgc agcatgctct     5400

acgcattcag tccttaaggg gtttatttta caaactgtgc gcctgtaagg tttattagca     5460

ataagataga aaattgagca agtttatacc ataattttgt agaaaaaaag aatctgctca     5520

gttccatatt tcatccgtga aaaacttgca atacgagcag tttcaaggaa taaataaaaa     5580

ggaaatgtaa accattgtaa aagtcttctg tcgaatgtgc ctgatgcatg tattatcgtc     5640

ttttatttca gaatacttca taaagataaa attaaattct atattatagt tggtgtattt     5700

acaatcttac catgtacatc acatcaaagt gatagctcta ctaatttaat ttccttgtca     5760

atgtttttaa ctatatagtg ctttaaagag attttttttc cctgtgtaaa aaaaaaaaaa     5820

aaaaa                                                                 5825


<210>  1725
<211>  3899
<212>  DNA
<213>  homo sapiens

<400>  1725
agtggcgtcc gttgtaagtg ctatgacaac agggcgaaga tggctcagag ttaggctgga       60

gaggggaggt gtcccttccg ctgcggccgt cgggtttctg ctacatccca ttcaccgcct      120

cctccatcct ttcctcctcg gtgtgagcag caggacttgc atttgttctc gcctgcctag      180

tgtcttccaa gggatagatg ccgtttcctc tgctggtctc tgggggtgac ggggggcgca      240

ggggagcttc ttgggggaat cactccaact ctgtggagct ggtggtgctg cctggtgggg      300

ctctctcttt gcccgggacg tggaacaact ttcagctgga ggacgagagg gaatagtgaa      360

gctaaaggtt gcttttctct gcaccgtccg ttcttgctcc ctctgctcca tcactgggac      420

cttgtcaggc gttcataaag caaaatttgc cgaacgaggg ttcgcagaaa ggtggggcag      480

agctcatctg acgtggcatc agtgtgaaag aaaatgtctt tatttaaagc ccgtgattgg      540

tggtctacta ttctgggaga taaagaagaa tttgatcaag gctgtttgtg tctggctaat      600

gttgacaata gtggaaatgg acaagataaa ataattgtgg gtagctttat gggataccta      660

aggatcttta gcccccatcc tgcaaaaaca ggagatggag ctcaagccga agatttgctt      720

ctagaagtgg atctacgaga tccagtactt caagtggaag taggaaagtt tgtttcaggt      780

accgaaatgc tacatttggc tgtgttacat tctagaaaac tttgtgtcta ctctgtctca      840

ggaaccttgg gtaatgtgga acatgggaac caatgtcaga tgaaattgat gtatgaacat      900

aatcttcaga gaacagcctg caatatgacc tatggatcat ttggtggtgt aaaaggtcga      960

gatttaattt gcatccagtc tatggatggg atgctgatgg tatttgagca ggagagctat     1020

gcttttggaa gatttctccc tggctttctt ctgcctggtc ctcttgccta cagttcccgt     1080

acagattcct tccttactgt ctcttcctgc caacaagtgg aaagttataa gtaccaggta     1140

cttgcttttg caacagatgc agataaaagg caggagactg aacagcaaaa acttggttct     1200

ggaaaaagac tagttgtgga ttggactcta aatattggag agcaagccct tgacatatgt     1260

attgtctctt tcaatcagtc ggcatcctct gtttttgttc ttggtgagag aaactttttt     1320

tgccttaagg ataatggaca aattcgattc atgaagaagc ttgattggag cccaagttgt     1380

tttctgccat attgctcagt ttctgaagga acaataaata ctttgattgg aaatcataat     1440

aacatgctgc atatttatca agatgtgaca ctgaagtggg ccacccaact tccccacatt     1500

cctgtagcag taagagtggg ctgtttgcat gatttaaagg gagtgatagt cactctgagt     1560

gatgatggtc acttgcagtg ttcatacctg gggacagatc cttctctgtt ccaagctcca     1620

aacgttcaat ctcgagaact aaactatgat gaacttgatg tagaaatgaa agaacttcag     1680

aaaatcatca aagatgttaa caaatcacaa ggtgtttggc ccatgactga gagagaagat     1740

gacttgaacg tttctgtcgt ggtttctcct aactttgatt cagtttctca agcgaccgat     1800

gttgaggtgg gaactgacct tgtcccttct gtcacggtga aggtcacact gcagaacaga     1860

gtgatattgc aaaaagccaa attatcagtc tacgtgcaac caccattaga attgacttgt     1920

gatcagttca cctttgaatt tatgagcatt ccgcgagtta tccaatgtaa atttagactt     1980

cccctaaagt taatttgcct accaggtcag ccttcaaaaa ctgcaagcca caaaattact     2040

attgatacca acaaatctcc agtcagtctt cttagtctct tcccaggttt tgccagtcag     2100

tcagatgatg atcaggtgaa tgtaatgggt tttcacttct taggaggtgc tcgaattact     2160

gttcttgctt ccaaaacttc tcaacgatat cgcattcaga gtgaacaatt tgaagatctt     2220

tggctcataa ccaatgagct tattcttcgc cttcaagaat attttgaaaa acagggagtc     2280

aaagattttg catgttcttt ttcgggatct ataccccttc aagaatattt tgagttgatt     2340

gatcatcatt ttgagctacg gataaatggt gaaaaattag aagaactctt atctgagaga     2400

gctgtacaat ttcgggccat tcaacgccgg ctactagcaa gattcaaaga taaaactcct     2460

gcccctcttc aacacctgga caccttgtta gatggaacct acaagcaggt aattgctcta     2520

gcagatgcag tggaggaaaa ccaaggcaat ctgttccagt cattcaccag gctgaagagt     2580

gccacccatt tggtgattct gctgatcgcg ctgtggcaga agcttagtgc tgaccaggtt     2640

gctattctgg aagcggcatt tctgccgcta caagaagaca ctcaagaatt gggctgggaa     2700

gaaacggtgg atgccgccat ttcccacctg ttgaagactt gcctgtcgaa gagttctaag     2760

gagcaggctt tgaacctcaa cagccagctg aacataccca aagacacaag ccaactgaag     2820

aaacatatca ccttgctctg cgatagatta tccaaaggtg gccgtctctg cctaagtacc     2880

gatgcagcag ccccacagac catggtcatg ccaggtggtt gtactacaat cccagagtca     2940

gacctagaag aaagatcagt agaacaagac tctacagaac tgtttaccaa ccacagacat     3000

ctcactgcag agacacccag gcctgaagtt tcacccctcc aaggagtctc ggaataattc     3060

aagtagagtt gtttggttga gaggaacatc cccatctcaa ggccgaacct gtgtgaacct     3120

catgccaagc acagatatag ggctggcgca ggtgcttcct aaagctcacc ttcctggaga     3180

tgacatgcat agaaagaggg gttgggactt tttacttcac taggagaact tgtaacacca     3240

tggggaagtc agctgaaact tgtcttgttt tgccaggaaa ggaagtagtt gcctttggtc     3300

atccatctgc taatagtcac agaatacagt gaaatgacat agttttgggt tagattttat     3360

aatgcaaaga ttcagatcca aaataatttc ataccccatt ttttcacaga attcttatat     3420

agtaaatgta tcaagtttaa taaagcatct cattgtcaaa taatatcttg gattttattt     3480

ataattagag ggatttatga gtgattgctc tacattattt cttcaaagga aaggaaagga     3540

attgaagact ttgctactct ctggtaagac ttgaatgtga ttattttata aataaaagaa     3600

ccactatgaa actttcatgt gatttgttct attaagctaa acgtggaaga agggaagttt     3660

tctagtattg tatgaaaatg tttaaatatt ttcaaggaag ctagtacatt aacatcccct     3720

tttcattacc ccattgggtg gcacctttta aaaatccagg ttattaaagg attcacactt     3780

tattacagtt aaaatttaag gtttttatgt gtaagaagtg aaagaaactt tgctaatttc     3840

aagttcgaat tacagttgtg agattgattt atttaaataa aaatatgcct ttgccagtt      3899


<210>  1726
<211>  879
<212>  DNA
<213>  homo sapiens

<400>  1726
ctcctcacag aagcctggag ctgggcatcc aagaagaagc agcctcattt gttttctggt       60

gtcatcgtag gtggccacct atggcttttg ggaatgtaaa aagggcagct ctctggcatg      120

ttcctgactg aggatctcat aacatttaac ttgaggaact tcctcctttt ccagctttgg      180

gagtcaagct tctcacctgg ggcgggtggg ttctgcacca ccctcccacc ctccttcctc      240

cgtgtggacg atagagccac atccagcacc acggacagct cccgggcgcc ttcatctcct      300

cgtcctccag gcagcacaag ccattgtgga atctccacca ggtgtacaga acggtgcctc      360

tgcgtcctgc cactcaggac ctctcaagtc cccgatgtga tggctcctca gcatgatcag      420

gagaaattcc atgatcttgc ttattcctgt cttgggaagt ccttctccat gtctaaccaa      480

gatctatatg gctatagcac cagctctttg gctcttggct tggcatggct aagttgggag      540

accaaaaaga agaatgtact tcatctggtt gggctggatt ccctctgata agccttccca      600

gttgactgaa agatgaggct aggctctagc aagttgaagt caaaccagct ccttcaagaa      660

gctttgagca gaatgaagtg gggaggaccc agcttccagc ccaggaagcc cactgtacct      720

ggagccatct gggataagac tttgacccat gactcccata tccacagcct gtccatccta      780

gcccatccca gtttatcctg tatcatttga gctgggattc ccacatcctc tgagttggaa      840

gtcccatctc aagtcttcaa taaagactct tgaatattg                             879


<210>  1727
<211>  7329
<212>  DNA
<213>  homo sapiens

<400>  1727
gcagtactcg gagacagcgg acccgtgtca gtgacagctt ccggtttggt ttctccgcct       60

tctgcttggc tagagctatt ggggctcggt ggcggccgca gtggggtgga gggggcaggg      120

cgtggtgagg taaggtgagt gccgtagtgg ggttccctgg agccatggcc tgctccattg      180

tccagttctg ctacttccag gacctccagg ccgcccggga cttcctcttt cctcacctgc      240

gggaggagat cctcagcggc gccttgcgga gggaccccag taaatcaaca gactgggaag      300

atgatggttg gggagcatgg gaagaaaatg aaccacaaga acctgaagaa gaaggaaata      360

cttgcaaaac acaaaaaact tcctggctcc aagattgtgt tttatcctta tctccaacca      420

atgatcttat ggtgatagct cgagagcaaa aagctgtatt tctagtgcca aaatggaaat      480

atagtgataa aggaaaggaa gaaatgcaat ttgctgttgg ctggagtggt tccttaaatg      540

tcgaagaagg ggaatgtgta accagtgctc tatgtatccc actagcaagc caaaagagga      600

gttccactgg gcgtcctgac tggacctgca ttgtggtggg ttttacttca ggttatgtac      660

gcttctacac tgagaatggt gtgctcttgc ttgcacagct tttgaatgag gacccagtac      720

ttcaacttaa atgcagaacc tatgaaatac cacgacatcc cggcgtgact gagcagaatg      780

aagagttgag tatcttatat ccagctgcca ttgtgactat tgatggattt agcctttttc      840

aatctcttcg tgcttgtcga aatcaggtag caaaagctgc agcatcaggc aatgagaaca      900

tacaaccacc accattagct tataagaaat ggggtctaca agatattgac actattattg      960

atcatgctag tgttggtatt atgactctgt ccccctttga tcaaatgaag actgcctcca     1020

atataggtgg atttaatgca gcaattaaaa atagtccacc tgccatgtct cagtatatca     1080

ctgtagggtc caatccattt actggcttct tctatgcttt agagggaagc acacaaccat     1140

tattatccca tgttgcacta gcagttgcaa gtaaactcac ttctgcttta tttaatgctg     1200

ccagtggttg gcttggttgg aaaagtaagc acgaagaaga agctgtccaa aagcaaaagc     1260

cgaaggttga gccagctacc ccattagctg taagatttgg acttccagat tctagacgcc     1320

atggtgaaag catatgtctg tctccatgta acacactggc agcagtaaca gatgatttcg     1380

gcagagttat tttattggat gtagctagag gaattgcaat acgcatgtgg aaagggtacc     1440

gcgacgcaca aattggatgg attcaaactg tagaggacct ccatgaaaga gtgccagaaa     1500

aggcagattt ttcccccttt ggaaattctc agggtccaag tcgagtagct caattccttg     1560

tgatctatgc gccaagaagg ggaattttag aagtgtggag cacacagcag ggacctagag     1620

taggagcttt caatgtgggg aagcactgca ggctgctgta tcctggctat aaaataatgg     1680

gtttaaataa tgttaccagt cagagttggc agccacagac ttatcagatc tgtctggttg     1740

atccagtgtc tggaagtgtg aaaacagtga acgttccctt ccatttagca ctgagtgata     1800

agaagagtga acgagccaag gatatgcacc tagtgaagaa actagcagcc ttactgaaaa     1860

caaaatctcc caatcttgat ttggttgaaa cagaaataaa ggaattaatt cttgatatta     1920

aataccctgc aaccaaaaaa caagctttgg aaagcatttt ggcaagtgaa cgtttaccat     1980

tttcttgcct tagaaacatc actcagactt taatggacac tttaaaaagt caagaacttg     2040

agtctgttga tgaaggattg ctacagtttt gtgccaataa actaaaactg ctgcaactct     2100

atgagtctgt cagtcaatta aattcccttg attttcattt agacacacca ttctctgata     2160

atgacttggc tctgttacta aggcttgatg aaaaagaact gcttaagctc caggcattac     2220

tagagaaata taagcaagag aacaccagga caaatgttcg attttctgat gataaagatg     2280

gtgtgttgcc tgtaaaaaca ttcttggaat atttagaata tgaaaaggat gtgctcaaca     2340

taaagaaaat aagtgaagag gaatatgtgg ctttaggtag tttctttttt tggaagtgtt     2400

tgcatggaga aagctccact gaggatatgt gtcacacttt ggagtcggct ggtcttagcc     2460

ctcagctgtt gttgtctctg ctcctgagtg tttggctttc aaaggaaaag gatattttgg     2520

ataaaccaca gtcaatctgc tgtcttcata ccatgctgtc cctcctgagc aagatgaaag     2580

tggccatcga tgagacctgg gattctcagt ctgtgtcccc atggtggcag cagatgcgca     2640

cagcctgtat tcagtctgag aacaatggag ccgctctgtt gtctgcgcat gttgggcatt     2700

ctgttgctgc acagatatca aacaacatga cagagaaaaa attttcccaa acagttttgg     2760

gtgctgattc agaggccctc actgattcct gggaggcact ttctcttgac actgagtact     2820

ggaaactcct tctgaaacag ctggaggatt gtctcatact tcagactctg cttcacagca     2880

aagggaacac tcagacctcc aaagtgtcat cactgcaggc tgagccactt ccaaggcttt     2940

ctgttaaaaa gttattagaa ggaggaaaag gtggcattgc agacagtgta gccaagtgga     3000

tatttaaaca ggacttcagc cctgaagtat taaaactggc taatgaagaa agagatgcag     3060

aaaacccaga tgaacccaaa gaaggtgtta acagaagttt ccttgaggta tcagagatgg     3120

agatggactt aggagccata ccagacttac tgcatttagc ctatgagcag tttccttgta     3180

gccttgagct cgatgtcttg catgcacatt gctgctggga gtacgttgtt cagtggaata     3240

aagatccaga ggaagcacgt ttttttgtta ggtcaataga acacttgaag caaatattta     3300

atgcacatgt tcaaaatggc attgcactga tgatgtggaa tacgttctta gttaaaagat     3360

tttctgctgc tacatactta atggataagg ttggaaaatc accaaaagat aggttatgcc     3420

gaagggatgt gggaatgagt gacacagcaa tgacatcttt cctcggctcc tgtttggatc     3480

ttcttcagat cttaatggag gcagatgtta gcagggatga aatacaggtg cctgtgctgg     3540

atactgagga tgcgtggctc tccgtggaag gaccaatctc catagtggaa ctggcccttg     3600

aacagaagca catccactac ccactggtgg agcaccactc catcctgtgc tccatcttgt     3660

atgcagtcat gaggttttct ctgaagaccg tgaagccact ttcacttttt gacagtaagg     3720

gaaaaaatgc atttttcaaa gacctaactt caattcagtt attacctagt ggggaaatgg     3780

atccaaattt tatttctgta cgacaacagt tcttattgaa agttgtcagt gcagctgtcc     3840

aggcccaaca ttcagccaca aaggtcaaag atcccacaga agaggccaca cccactcctt     3900

ttgggaaaga ccaagattgg ccagctctag ctgtggattt agcccatcac cttcaagtta     3960

gtgaagatgt tgttagaagg cattatgtgg gggaactata caactatgga gttgaccact     4020

taggagaaga ggccattcta caggttcatg acaaagaggt ccttgcctct cagctgctgg     4080

tgctcacggg gcaaaggctg gctcatgcgc ttctccacac ccagacaaaa gaaggaatgg     4140

agctgcttgc cagacttcca cccacactgt gtacttggct gaaagcaatg gacccccagg     4200

accttcaaaa cactgaagtg ccaattgcaa caacagctaa actagtaaat aaagtaattg     4260

agcttttacc agaaaaacat gggcaatatg gtctagcctt acacctcatt gaagctgtgg     4320

aagccatatc tcttccttct ttatgacact tacctactgg aaatagtcta aaattatgat     4380

tataacatga agtagtgcat ggttatttta catagtaaga cctggaattt tatgggaaaa     4440

gtatgtcttt ttttttcctt ttgtaaaata aataaaagta tatacaactt ttaaaaagtg     4500

caaccctggc taaattccac tcctttggtt aatactgaag ataaaatata aacaaatgtc     4560

aactctgtta taattaatac agatgtttta ctgtttattt ctaattcaaa cacttaagta     4620

gctttattgt taaactttgc tatttaaaat tggttataat ttagattatg ttcttataag     4680

attctatatt tcctatctaa aatgttgttg taattcaatt taaatgtgtt catgtacagt     4740

ccccatcagt agcgtataga acaccccact ctcctttagt aaatgttgag aaaatgcctt     4800

tgttgtcatg ctccaaatcc cacactgggc tgccacctgg gagttctgga taccgaaagg     4860

ttcctttccc agaggttctg ctgttgccat cagaggagga tgaccgtgct tgaggaggaa     4920

gaatgggttc aagatcatca tattcatcag aaggggacac taaatagaac ccttaacctg     4980

ttgtacttgc caaaattgag aatcagagat gtgtaaaatg cagcaaatta attataatgt     5040

aagttaagat ttgctttttg ccaagttgca aagttgtatc cacatcaggt cactgtaaaa     5100

atgtattatc ttgtaaaact tatgtaaaaa aaaaaaaaaa aaaaaggcaa agatactaaa     5160

aattttaagt ccgactttat ttttcctaca agtgtttaga aatgcttctg ggatttgcta     5220

atattatctg tccttgggaa cagtattgaa aaaactgctt agtggtatta cagctttagc     5280

aaacctacct cacagctggg atgagaggat aaaatacaac taattttgta ccctatagtg     5340

cctagagcag tccaagtgct aaataaatat ttactgatta aaaccaaact atagctactc     5400

gggaggctgg aggaggatcg cttgagccca ggagtttgag gccattctgg gcaatatagc     5460

aagaccctgt ctcgaaaaaa aaaaaaaaaa gaaaaaacca aactaaccaa aactctgtaa     5520

aagagtgctt tgagctctac aaataccaag tatttattgt ggtatatttt tagaatgtag     5580

ccatacagtg taattatggg tatctgtcat ggatcacaat tattattcat agtaagtcat     5640

tgtgatacag aagtttgttt cttcacttcc ccttaagaag ccaactatag taatcatgca     5700

aagttgagga gtatgtcctt cagggatata aaaagaaaaa caaatctgtt ttttgagcta     5760

aaagagcaca tccaaacaag aatttaactg gctaaaattt agtaattact gttaagtaac     5820

tatcaaactt gaaatcttac aagataaatg gttaagatgt cttgagtatt tgggatgggg     5880

gcctgtgagt ctgattgaga catacatttt acagagtagc agcactggaa agggctagtc     5940

caacctccca gcctctgctt gggtctccgc tgccccagcc acacacatcc tagaattctt     6000

gtaaacatat ctggctctgt gttaacagtc acttgttata tgttttctaa gagattagtt     6060

cttcctgtga tttttccaag tacgctgaaa gtagtagtat gaacttaagg aggctagtca     6120

aagaaacttg gagttatagg tatttttaaa gaataaatcc tcaattccat catcacttgg     6180

cggggagggg gcacttatta agcattttag ataataaaac tggttaagct tactctggta     6240

gaacagacaa tcaaatctgg ggattgctga gaacaataat aagctgaagt atggctcaca     6300

gaatcctaac acaaatcatt aagtctctag ttagatttgt tatcctaaaa tttttcatag     6360

aattttaaaa tctaattctg acttgtatgg ttaagaaaag cagttaaata ttttactact     6420

tatcaagggc ttttaaaata aataaatctg attgatagga agaaaggcaa ataaatacct     6480

atgtagacat tctataataa caaagagcca tagatgataa aggaattaga ttttaatgta     6540

gaatgggtgg tttctgaaac aaaggtatgt ggtactttgt agttattgat gagaagccag     6600

taaccagtag tgttttccta gatatatgcc caccctcaca caactttctt cattaacaaa     6660

cattaaatat gcatttgtat cttattaaat tatattgtat aatgctgaag gaaaacaaaa     6720

agtgttcaaa taatcataac ttctacatta caggttctgt ttagatgcag aactagaggg     6780

gccagggtaa atgtagataa agagatatat agcaccatgc ttcttaatgc ttcatacttt     6840

tgcaaacaga aaaaaaaagt tttactttta ttataaaact tcatctatgg tcaaagtaaa     6900

cactgttaca tttaaattgc tttttaaaaa caattgcgat ctaaaaagtc aaaaatctga     6960

aatttaataa tatgagactt acactgaata taatgttcat ttagaagttg ctgtggtcca     7020

cttcatttat aaggaacaaa tatttttaca gtacactata gcaacagcaa aagccctctc     7080

tcaccctgat aggaatgggt ttgctgggtg tctagaagtt agattcctgc tgaatagaat     7140

tagccatcct taaaagattt taatccaata ctgaactgtt tataaaatgc tttctctatt     7200

gtaatgtact gtaagtagtg aaattctgta tatactgcta ttttctgtct gttcattgtt     7260

gtgaacttct tatgtatatt agtgaaataa attttcagct ttcatgttgt ttcctaaaca     7320

ttcataagt                                                             7329


<210>  1728
<211>  6628
<212>  DNA
<213>  homo sapiens

<400>  1728
ctcctcggtg caacctatat aaggctcaca gtctgcgctc ctggtacacg cgcttcaact       60

tcggttggtg tgtgtcgaag aaacctgact gcgccctgag gagaacagcg gagaaggtcc      120

accgagcctg gcgaaaggtc cgctgagcgg gctgtcgtcc ggagccactc cgggctgcgg      180

agcacccagt ggagaccgcg cctggctcag gtgtgggacc ccatccttcc tgtcttcgca      240

gaggagtcct cgcgtgaaat aagcgggttt tgaaaacaaa aaaaagaagg agtggaagag      300

ggggccagga tccaggcctc catccccaca gaagtgaagc tacagctggg aggtctcctc      360

ccaccccaac cgtcaccctg ggtcccgact gcccacctcc tcctcctccc cctcccccca      420

acaacaacaa caacaacaac tccaagcaca ccggccataa gagtgcgtgt gtccccaaca      480

tgaccgaacg aagaagggac gagctctctg aagagatcaa caacttaaga gagaaggtca      540

tgaagcagtc ggaggagaac aacaacctgc agagccaggt gcagaagctc acagaggaga      600

acaccaccct tcgagagcaa gtggaaccca cccctgagga tgaggatgat gacatcgagc      660

tccgcggtgc tgcagcagct gctgccccac cccctccaat agaggaagag tgcccagaag      720

acctcccaga gaagttcgat ggcaacccag acatgctggc tcctttcatg gcccagtgcc      780

agatcttcat ggaaaagagc accagggatt tctcagttga tcgtgtccgt gtctgcttcg      840

tgacaagcat gatgaccggc cgtgctgccc gttgggcctc agcaaagctg gagcgctccc      900

actacctgat gcacaactac ccagctttca tgatggaaat gaagcatgtc tttgaagacc      960

ctcagaggcg agaggttgcc aaacgcaaga tcagacgcct gcgccaaggc atggggtctg     1020

tcatcgacta ctccaatgct ttccagatga ttgcccagga cctggattgg aacgagcctg     1080

cgctgattga ccagtaccac gagggcctca gcgaccacat tcaggaggag ctctcccacc     1140

tcgaggtcgc caagtcgctg tctgctctga ttgggcagtg cattcacatt gagagaaggc     1200

tggccagggc tgctgcagct cgcaagccac gctcgccacc ccgggcgctg gtgttgcctc     1260

acattgcaag ccaccaccag gtagatccaa ccgagccggt gggaggtgcc cgcatgcgcc     1320

tgacgcagga agaaaaagaa agacgcagaa agctgaacct gtgcctctac tgtggaacag     1380

gaggtcacta cgctgacaat tgtcctgcca aggcctcaaa gtcttcgccg gcgggaaact     1440

ccccggcccc gctgtagagg gaccttcagc gaccgggcca gaaataataa ggtccccaca     1500

agatgatgcc tcatctccac acttgcaagt gatgctccag attcatcttc cgggcagaca     1560

caccctgttc gtccgagcca tgatcgattc tggtgcttct ggcaacttca ttgatcacga     1620

atatgttgct caaaatggaa ttcctctaag aatcaaggac tggccaatac ttgtggaagc     1680

aattgatggg cgccccatag catcgggccc agttgtccac gaaactcacg acctgatagt     1740

tgacctggga gatcaccgag aggtgctgtc atttgatgtg actcagtctc cattcttccc     1800

tgtcgtccta ggggttcgct ggctgagcac acatgatccc aatatcacat ggagcactcg     1860

atctatcgtc tttgattctg aatactgccg ctaccactgc cggatgtatt ctccaatacc     1920

accatcgctc ccaccaccag caccacaacc gccactctat tatccagtag atggatacag     1980

agtttaccaa ccagtgaggt attactatgt ccagaatgtg tacactccag tagatgagca     2040

cgtctaccca gatcaccgcc tggttgaccc tcacatagaa atgatacctg gagcacacag     2100

tattcccagt ggacatgtgt attcactgtc cgaacctgaa atggcagctc ttcgagattt     2160

tgtggcaaga aatgtaaaag atgggctaat tactccaacg attgcaccta atggagccca     2220

agttctccag gtgaagaggg ggtggaaact gcaagtttct tatgattgcc gagctccaaa     2280

caattttact atccagaatc agtatcctcg cctatctatt ccaaatttag aagaccaagc     2340

acacctggca acgtacactg aattcgtacc tcaaatacct ggataccaaa cataccccac     2400

atatgccgcg tacccgacct acccagtagg attcgcctgg tacccagtgg gacgagacgg     2460

acaaggaaga tcactatatg tacctgtgat gatcacttgg aatccacact ggtaccgcca     2520

gcctccggta ccacagtacc cgccgccaca gccgccgcct ccaccaccac caccgccgcc     2580

gcctccatct tacagtaccc tgtaaatacc tgtcatgtcc ttcaggatct ctgccctcaa     2640

aatttattcc tgttcagctt ctcaatcagt gactgtgtgc taaattttag gctactgtat     2700

cttcaggcca cctgaggcac atcctctctg aaacggctat ggaaggttag ggccactctg     2760

gactggcaca catcctaaag caccaaaaga ccttcaacat tttctgagag caacagagta     2820

tttgccaata aatgatctct catttttcca ccttgactgc caatctaact aaaataatta     2880

ataagtttac tttccagcca gtcctggaag tctgggtttt acctgccaaa acctccatca     2940

ccatctaaat tataggctgc caaatttgct gtttaacatt tacagagaag ctgatacaaa     3000

cgcaggaaat gctgatttct ttatggaggg ggagacgagg aggaggagga catgactttt     3060

cttgcggttt cggtaccctc tttttaaatc actggaggac tgaggcctta ttaaggaagc     3120

caaaattatc ggtgcagtgt ggaaaggctt ccgtgatcct ctcgctgcac ccttagaaac     3180

ttcaccgtct tcaaactcca tttccatggt tctgttaatt ctcaaggagc agcaactcga     3240

ctggttctcc caggagcagg aaaaaccctt gtgacatgaa acatctcagg cctgaaaaga     3300

aagtgctctc tcagatggac tcttgcatgt taagactatg tcttcacatc atggtgcaaa     3360

tcacatgtac ccaatgactc cggctttgac acaacacctt accatcatca tgccatgatg     3420

gcttccacaa agcattaaac ctggtaacca gagattactg gtggctccag cgttgttaga     3480

tgttcatgaa atgtgaccac ctctcaatca cctttgaggg ctaaagagta gcacatcaaa     3540

aggactccaa aatcccatac ccaactctta agagatttgt cctggtactt cagaaagaat     3600

tttcatgagt gttcttaatt ggctggaaaa gcaccagctg acgttttgga agaatctatc     3660

catgtgtctg cctccatatg catctgggca tttcatcttc agtcccctca ttagactgta     3720

gcattaggat gtgtggagag aggagaaatg atttagcacc cagattcaca ctcctatgcc     3780

tggaaggggg acatctttga agaagaggaa ttagggctgt ggacactgtc ttgaggatgt     3840

ggacttcctt agtgagctcc acattacttg atggtaacca cttcaaaagg atcagaatcc     3900

acgtaatgaa aaaggtccct ctagaggatg gagctgatgt gaagctgcca atggatgaaa     3960

agcctcagaa agcaactcaa aggactcaaa gcaacggaca acacaagagt tgtcttcagc     4020

ccagtgacac ctctgatgtc ccctggaagc tttgtgctaa cctgggactg cctgacttcc     4080

tttagcctgg tcccttgcta ctaccttgaa ctgttttatc taacctctct ttttctgttt     4140

aattctttgc tactgccatt gaccctgctg caggatttgt gtcattttcc tgcctggttg     4200

ctgagactcc attttgctgc cacacacaga gatgtaagag gcaggcttta attgccaaag     4260

cacagtttga gcagtagaaa acaacatggt gtatatctca aattgcctga catgaagagg     4320

agtctaacgg tgaagtttca cttttcatca gcatcatctt tcacatgttc attatcatct     4380

gctcttattc ttgcatgttt aaacacttaa aatttttagt ataattttta gtgtgttttg     4440

aagtggtgac taggctttca aaaacttcca ttgaattaca aagcactatc cagttcttat     4500

tgttaaacta agtaaaaatg ataagtaaca tagtgtaaaa tattccttta ctgtgaactt     4560

cttacaatgc tgtgaatgag aggctcctca gaactggagc atttgtataa taattcatcc     4620

tgttcatctt caattttaac atcatatata atttcaattc tatcaattgg gcctttaaaa     4680

atcatataaa aggatataaa atttgaaaag agaaacctaa ttggctattt aatccaaaac     4740

aacttttttt ttccttcaat ggaatcagaa agcttgtcaa tcactcatgt gttttagagt     4800

aattactttt aaaatggtgc atttgtgctt ctgaactatt ttgaagagtc acttctgttt     4860

acctcaagta tcaattcatc ctccatacat ttgaattcaa gttgtttttt tgtcaaattt     4920

acagttgtca attgatcttc aagctgcagg gtgcctagaa atgggccgtt gtctgtagcc     4980

ctggcatgtg cacacggaca tttgccacca ctgcaagcaa aagtctggag aagttcacca     5040

acgacaagaa cgattaggga aaatatgctg ctgtgggtta acaactcaga aagtccctga     5100

tccacatttg gctgtttact aaagcttgtg attaactttt tggcagtgtg tactatgctc     5160

tattgctata tatgctatct ataaatgtag atgttaagga taagtaattc taaatttatt     5220

attctatagt tttgaagttt ggttaagttt cctttcactc aattgattta ttttgttgtt     5280

aatcaaattt atgttaattg gatcctttaa attttttttg gcattttcca acaaaaatgg     5340

ctttattcat aagaaaggaa aaaaatcaat ggaatttgat atctaaagaa gttagaaagg     5400

gagcaaaata aaaaacataa aggagataga tgaattagta agcaaatcag tagtcgagtt     5460

tttcaaactg gcaaaattaa ttaattgact tttagcccaa atttacattg ttaattaaat     5520

caagaaggaa gaagatctaa gagctcccat tgataggcaa gcctagagag aactagctaa     5580

atttatcatg ctaggatatt gaaacacaga aagtttacat acatttatga agggtcaatt     5640

tagtttggac agtgaggtat ttgtcttagt ggaaaaaagg agaattagtc tgatcaaatc     5700

gtgaagtaat acagtgaact tgcaggtgca caaaataaga gggccacatc tatatggtgc     5760

agtctggaat tctgtttaag tttgtaggta cctcttggac ttctgaattg atccagttgt     5820

catccaccac agacatctca catcagatac agacagttcc aagattgaca acagagaaca     5880

acctgctgga aagacctggg cagaaatgga gagccctgcg ggaaccatgc tacattttca     5940

tctaaagaga gaatgcacat ctgatgagac tgaaagttct ttgttgtttt agattgtaga     6000

atggtattga attggtctgt ggaaaattgc attgctttta tttctttgtg taatcaagtt     6060

taagtaatag gggatatata atcataagca ttttagggtg ggagggacta ttaagtaatt     6120

ttaagtgggt ggggttattt agaatgttag aataatatta tgtattagat atcgctataa     6180

gtggacatgc gtacttactt gtaacccttt accctataat tgctatcctt aaagatttca     6240

aataaactcg gagggaactg cagggagacc aacttattta gagcgaattg gacatggata     6300

aaaaccccag tgggagaaag ttcaaaggtg attagattaa taatttaata gaggatgagt     6360

gacctctgat aaattactgc tagaatgaac ttgtcaatga tggatggtaa attttcatgg     6420

aagttataaa agtgataaat aaaaaccctt gcttttaccc ctgtcagtag ccctcctcct     6480

accactgaac cccattgccc ctacccctcc ttctaacttt attgctgtat tctcttcact     6540

ctatatttct ctctatttgc taatattgca ttgctgttac aataaaaatt caataaagat     6600

ttagtggtta agtgcaaaaa aaaaaaaa                                        6628


<210>  1729
<211>  3760
<212>  DNA
<213>  homo sapiens

<400>  1729
gccgccgaag gggactgttt gctcctacgg gctgtagatg gagctgtccg gccccggaga       60

gggggaaggc gcctggaaaa cgttcttctt ctccctggcc gacccgagcg gggaacagca      120

ctcccaggat gcagtttgtg tcaacacggc cgcagcctca gcagctgggc atccagggcc      180

tggggctgga cagcgggagc tggagctggg cccaggctct gcccccggag gaggtctgcc      240

accaggagcc ggcgctgcgc ggggaaatgg ccgagggaat gccgcccatg caggctcaag      300

aatgggacat ggacgcccgg cggccaatgc cttttcagtt cccacccttt ccagataggg      360

cacctgtctt ccccgaccgc atgatgcgag agccccagtt gcccacagca gagatctcac      420

tctggactgt ggtggctgcc attcaggctg tggagaggaa ggtggatgcc caggccagcc      480

agctgctgaa cctggagggg cgcacgggga cagccgagaa gaagctggcc gactgtgaaa      540

agacggccgt ggaatttggg aaccacatgg agagcaagtg ggccgtgctg gggaccctgc      600

tgcaggagta cgggctgctg cagaggcggc tggagaactt ggagaacttg ctgcgcaaca      660

ggaacttctg ggtcctgcgg ctgcccccgg gcagcaaggg ggaggccccc aaggttccag      720

tgacttttgt cgacattgct gtgtacttct ccgaagacga gtggaagaac ttggacgaat      780

ggcagaagga gctttataac aaccttgtta aggagaacta caaaaccctc atgtccctgg      840

acgcggaggg ctcagtcccc aagccagatg ctccagtcca ggctgagccc agggaagaac      900

cttgtgtgtg ggagcagcgc caccccgaag agagagaaat cccaatggat cccgaagcag      960

gagcagagcc cctggtgcct gcgcaggatg cgtcctccca ggtgaagcgt gaggacaccc     1020

tgtgtgtccg gggtcagcgg ggcctggagg aaagagccat ccctacggaa tccattaccg     1080

actccccaat ttctgcccag gacctcttgt cccggattaa acaggaggag catcagtgcg     1140

tgtgggatca gcaggatttg gcagacagag atattcccac ggatcccaat tcagagtctc     1200

tcatctcagc acatgacatt ttgtcatgga tcaagcagga ggagcagcca tacccatggg     1260

gaccacgcga ctcaatggac ggagagcttg gattagactc tggccctagt gacagcctgc     1320

tgatggtgaa gaacccaccc ccggccccgc cacagcccca gccccagccc cagccaccgc     1380

agccgcagct gcagtcgcag ccccagcccc agagcctgcc ccccatcgcg gtggccgaga     1440

acccgggcgg ccccccgagc cgagggctgc tggacgacgg tttccaggtg ctgcccgggg     1500

agcgtggctc cggcgaggcg ccgccgggtg gggaccgcag caccgggggc ggcgggggcg     1560

atgggggcgg tgggggcggc ggcgcggagg cggggacggg ggcaggcggc ggctgtggca     1620

gctgctgccc tggcgggctg cggcggagcc tcctcctgca cggcgcccgc agcaagccct     1680

actcgtgccc cgagtgcggc aagagcttcg gcgtgcgcaa gagcctcatc atccaccacc     1740

gcagccacac caaggagcgg ccctacgagt gcgctgagtg cgagaagagc ttcaactgcc     1800

actcgggcct catccgccac cagatgacgc accgcggcga gcggccctac aagtgctcgg     1860

agtgcgagaa gacctacagc cgtaaggagc acctgcagaa ccaccagcgg ctgcacacgg     1920

gcgagcggcc tttccaatgt gcactgtgcg gcaagagctt catccgcaag cagaacctgc     1980

tcaagcacca gcgcatccac acgggcgagc gcccctacac gtgcggcgag tgcggcaaga     2040

gcttccgcta caaggagtcg ctcaaggacc acctgcgcgt gcacagcggc ggcccgggcc     2100

ccggcgcccc acggcagctc ccgccgcctc ctgagcgaga ctagggctgg gctgggggag     2160

ggcagggccg gacggagtgg atcgggggcg gcctgagcac caaccacctt gccgggtgtc     2220

ctcagccacc gtctggaaat cggcaacagg cattgcactc cggttggggg tcccccaggg     2280

tggggcaggg atcccccaga tctgtctggt ctgaatggac gcccagctca tctagggtgg     2340

acccagctgc tggggaagag ccagggggac cgcgaggagc cgagcgtcct cgggcaccgc     2400

cctcacacct cctcgagtgc cctgggacca ctgggccaca gatggtcatc aggggaagcc     2460

accagggagt cccgaagccc ttctgagatc aggaaatcag gtcccaaggt taggagacgc     2520

cctgaaaaaa agcgaaggcc gagggatgtg ctaagggtaa caccttcatg atgacaacac     2580

tgcctcgcgt ttcaatagcg ctttatactt ttttaagtgt tttctatccg ttatccattt     2640

cacccttggc ctatccctct cagataggtg gggtaggatt ttcctggtga ccgagtaaag     2700

tgagaggcag gtgagacggt tcacccaatc acacgggaag gggcgcgcgc tgcccaaccg     2760

cgctctccgc ctacctccgc tgctcgggaa gctgctggcc tggccctcct ggtctctctt     2820

cctttcctgg tctctcttcc tttccttgct ctcacccacg gataaaacca gaagcgacag     2880

gaggccagct cctggggttc ctgggagccg ggaacagatt ggctacggaa cgccccaggt     2940

tgtacattca gagggctctt tctccatggg agctcctggt gccgcctcgg ccccagcctg     3000

tccccagccc ctcaatctgg tgcagcagca tcttgtcact gcacaacagt ggcctggtcc     3060

cccacaggca gttagggccc caggtcagac ctcaccatga tgatttgttc cagttctccc     3120

agggcagagg ggcgagggag aggcttttgc tgtgagagta gccgtcacgt gtctcttccc     3180

agcagcgccg ggcaagtggg tgctagagtc tgagcctcag gctctcctgc cctgggcctc     3240

ccaattggtg ctatctgtta ctgcccgtgc tcacggacat ggatacagac cctgctgtgc     3300

tccacaccct gcaggcgcct cgggaagcgc ccaaaggatt ccccttcacg ttggtgcacc     3360

tgctccatag ctccgggcgc tgcgtcccga ggggccacag tctccatttc agcgtcttgc     3420

atggcctggc accgggtggg gtggtatgcc ccaggaccct tgtttgtgtc aaaaatgact     3480

ttccctgccc ttgccgtggg tccggcgttc ctcccagccg ggatcacagt gggcagccgg     3540

cacccggcac cactttggcg agcgtcctgc ttccgccctc gccctcatct acgctgctcc     3600

gctttcctca gacccctttt tgccgtgcaa agggaattct tgacattaaa taaaaggtat     3660

ccagattgca gactgcatgt tcacagagct gggggttctc cagcttgcct acagtaaagc     3720

ctcaatgaac tggaatccaa ttcaaaaaaa aaaaaaaaaa                           3760


<210>  1730
<211>  5240
<212>  DNA
<213>  homo sapiens

<400>  1730
atctttgatc aatgtacttg ccagggagag cccaagtcct tcaaacctcc tccttttcac       60

cttcatcctt aactttgtgc tagagcgaga cccacacaac aacagccgac cctccccgcc      120

ccacccccac ccccaaacca gccctcgatc ccagcccccg gagaggactc gcatttcgac      180

ttgcgggaca cttttgtgcg ttcctctcca gagcgcctct cgtgctcgcc cctcttgcgc      240

tcgctcttta ttaccttcac ctccttttct cccccttctc tccctttctc cttctcgttc      300

tctcccggag ttgttgttgc ccccctcgct ccttctcccc ccttttttcc ccttcccctc      360

ccgggggtgt gtggcaactt ttcctctcgc ttctcctccg tctgtttccc cttatatgtg      420

accatggcag tgccggcggc tttgatccct ccgacccagc tggtcccccc tcaaccccca      480

atctccacgt ctgcttcctc ctctggcacc accacctcca cctcttcggc gacttcgtct      540

ccggctcctt ccatcggacc cccggcgtcc tctgggccaa ctctgttccg cccggagccc      600

atcgcttcgg cggcggcggc ggcggccaca gtcacctcta ccggcggcgg cggcggcggc      660

ggcggcagcg gaggcggcgg cggcagcagc ggcaacggag gcggcggtgg cggcggcggc      720

ggtggcagca actgcaaccc caacctggcg gccgcgagca acggcagcgg cggcggcggc      780

ggcggcatca gcgctggcgg cggcgtcgct tccagcaccc ccatcaacgc cagcaccggc      840

agcagcagca gcagcagtag cagcagcagc agcagcagca gtagtagcag cagcagcagt      900

agcagcagca gctgcggccc cctccccggg aaacccgtgt actcaacccc gtccccagtg      960

gaaaacaccc ctcagaataa tgagtgcaaa atggtggatc tgaggggggc caaagtggct     1020

tccttcacgg tggagggctg cgagctgatc tgcctgcccc aggctttcga cctgttcctg     1080

aagcacttgg tggggggctt gcatacggtc tacaccaagc tgaagcggct ggagatcacg     1140

ccggtggtgt gcaatgtgga acaagttcgc atcctgaggg gactgggcgc catccagcca     1200

ggagtgaacc gctgcaaact catctccagg aaggacttcg agaccctcta caatgactgc     1260

accaacgcaa gttctagacc tggaaggcct cctaagagga ctcaaagtgt cacctcccca     1320

gagaactctc acatcatgcc gcattctgtc cctggtctca tgtctcctgg gataattcca     1380

ccaacaggtc tgacagcagc cgctgcagca gctgctgctg ctaccaatgc agctattgct     1440

gaagcaatga aggtgaaaaa aatcaaatta gaagccatga gcaactatca tgccagtaat     1500

aaccaacatg gagcagactc tgaaaacggg gacatgaatt caagtgtcgg actggaactt     1560

ccttttatga tgatgcccca ccctctaatt cctgtcagcc tacctccagc atctgtcacc     1620

atggcaatga gccagatgaa ccacctcagc accattgcaa atatggcagc agcagcacaa     1680

gttcagagtc ccccatccag agttgagaca tcagttatta aggagcgtgt tcctgatagc     1740

ccctcacctg ccccctctct ggaggagggg agaaggcctg gcagtcaccc atcatcacat     1800

cgcagcagca gcgtgtccag ctcccctgct cggactgaga gctcttctga cagaatcccg     1860

gtccatcaga atgggttgtc catgaaccag atgctgatgg gcttatcacc aaatgtactt     1920

cctgggccca aagagggaga tttggccggt catgacatgg gacatgagtc aaaaaggatg     1980

catattgaaa aagatgagac cccgctttct acaccaaccg caagagacag ccttgacaaa     2040

ctctctctaa ctgggcatgg acaaccactg cctccaggtt ttccatctcc ttttctgttt     2100

cctgatggac tgtcttccat cgagactctt ctgactaaca tacaggggct gttgaaagtt     2160

gccatagata atgccagagc tcaagagaaa caggtccaac tggaaaaaac tgagctgaag     2220

atggattttt taagggaaag agaactaagg gaaacacttg agaagcagtt ggctatggaa     2280

caaaagaata gagccatagt tcaaaagagg ctaaagaagg agaagaaggc aaagagaaaa     2340

ttgcaggaag cacttgagtt tgagacgaaa cggcgtgaac aagcagaaca gacgctaaaa     2400

caggcagctt caacagatag tctcagggtc ttaaatgact ctctgacccc agagatagag     2460

gctgaccgca gtggcggcag aacagatgct gaaaggacaa tacaagatgg aagactgtat     2520

ttgaaaacta ctgtcatgta ctgaatcttt cctgttgaag aaatccatgt tatagaaaag     2580

aactttgcag tcagacattc gtcatgggaa agttcagaaa aaaataaagt ccttttaagg     2640

gaacttcctg aattttgtgt attaatgttc tttaaaagtt taagtattct acaaaaaaaa     2700

aaaaagtttt ctccattgat tttcacctgt ggttcatacc agagacctga gaatgtttgt     2760

aaatgtacaa gtatcaaagt tcttacagtt aattactgca acttgctgct ggacaattgt     2820

atacagagtt aaaggcaggt ctgaataaga cctagctttg tttttttcta atggaatgaa     2880

ccattttcct cttctgaaaa ttctgtatct gagcacatca agagactctt gtagcagtgg     2940

ttacccagac ttacagaatt atgtcctcca gaaaccagca agaacacttg gaatgaacga     3000

atgaacttgt agggggcata gaggattctt gaaaaaaaaa aatgcaagag tgattttctg     3060

ttacattcaa tttcaaactc tctaattgtg ggttttctcc tgaagaattt tttttcacat     3120

actttccaaa agaccaacaa atggatgttg acaacaaccc aatgaaataa cattttgcat     3180

atctgaaaag aagcattgaa tataagccaa aagctttcac tgaaggtttt tttttcttaa     3240

aaataaaaaa aaatatataa gtgtaacatg ttttcattcc aaactggtag tggtatatag     3300

aattaaagat aataatgttg cttcttattc aaactgttgg tcatatgtac agtatataaa     3360

cataaaacac acaaggaagg tattatgtat gcagtagtat actagagttt aggaaaatga     3420

aaattttaga aaatatgttt tgtcaccctg ttggtcagaa agatgtcttt ctggttttaa     3480

cgcatgcagg catgtaaata tttgtctgga gtcacagtat taatgaatga gatcttaagc     3540

atctggtgac atcagaactc tgtgtcagcc acttttattt gtatattgaa ccctagctag     3600

tgccccaagc tgcactattg ggaatggatt gtggctgaac agcaaatcaa aacaccagaa     3660

atatttttat atgttaacgt catattatgt taatgttgct gaaaacaaaa cctaacaaac     3720

cttgatgtac cagtccaata ccatgtagcg ctgagtgata aagttaaaat gtgctgtgct     3780

tcccaccctt gtcagaggga agggtggcta tgtgttattt tcactgtctt tttgaaagtt     3840

acagtatgtg ttttcacttt cgtgcagata actggaagta aagcggcaaa cagtgcttat     3900

tacatgctaa agttaccttc tctttgtttt ttgcatatct ggaattacac ctttaaagac     3960

tgatatgaat cagtacggtc actatacatt ttatgatttt tctgtcatct taaaattgta     4020

tgatcgtaac attatttatt accacaaaac agcaaaatct tcaatgtcta agaaaactag     4080

cttaaaatgt ttaaatatag ttctgattgg gtattaatta cttgattaag aaaaaattaa     4140

cattatagat actctggcat tacgcttcta taccttttag gtcttccttg caatactgga     4200

acataattct tttgtgtagc tcactattag ccagctaagt tcatcttttt aataccataa     4260

aaaggttata tgtacagttc ctattttagc ttgcttacaa agggagcatt atttttattt     4320

aaagtattgc tagtaaatga tttgtagaaa cttggttttc taagcatagt tcttccataa     4380

ccaccttttg ttgtttgagc acaagggatt cttttcctag ttctatgtgt ttgtttccct     4440

atatgcagtc tttaaaggat tacaacactt aaaattgaat ggacttgtgt caagcttttt     4500

gcatcataca ttttttgaaa gatttttaaa aaagcctaca acttacatat gtagtagaat     4560

cagccattgc tctgctcctg gcatagagtc acctgtttgt tatgtggatt aaatagtttt     4620

aaaatacata tttgaagacc tttgagaatg ctttagtgtt tgatttgaaa taaaaggaaa     4680

ttttagcaag gattaaagaa aaaagctatc agctgtatgt taagagagac tcttactaac     4740

atgttgtaaa tattacaatt catgaaatgt tattgtaagt ctgtaactta attttttccc     4800

tgttttagtt atacaggttg gtttggaaat ttgtgttttg gcataaacaa gtaaaatgtg     4860

cccattttat ggtttccatg cttttgtaat cctaaaaata ttaatgtcta gttgttctat     4920

attataacca catttgcgct ctatgcaagc ccttggaaca gaacatactc atcttcatgt     4980

aggacctatg aaaattgtct atttttatct atatatttaa agttttctaa aaatgataaa     5040

aggttattac gaattttgtt gtacaaaatc tgtacaaaaa tctgttttta catcataatg     5100

caagaattgg aaatttttct atggtagcct agttatttga gcctggtttc aatgtgagaa     5160

ccacgtttac tgttattgta tttaattttc ttttcctttt caacaatctc ctaataaaac     5220

tgtctgaaat ctcaaaaaaa                                                 5240


<210>  1731
<211>  4796
<212>  DNA
<213>  homo sapiens

<400>  1731
atctttgatc aatgtacttg ccagggagag cccaagtcct tcaaacctcc tccttttcac       60

cttcatcctt aactttgtgc tagagcgaga cccacacaac aacagccgac cctccccgcc      120

ccacccccac ccccaaacca gccctcgatc ccagcccccg gagaggactc gcatttcgac      180

ttgcgggaca cttttgtgcg ttcctctcca gagcgcctct cgtgctcgcc cctcttgcgc      240

tcgctcttta ttaccttcac ctccttttct cccccttctc tccctttctc cttctcgttc      300

tctcccggag ttgttgttgc ccccctcgct ccttctcccc ccttttttcc ccttcccctc      360

ccgggggtgt gtggcaactt ttcctctcgc ttctcctccg tctgtttccc cttatatgtg      420

accatggcag tgccggcggc tttgatccct ccgacccagc tggtcccccc tcaaccccca      480

atctccacgt ctgcttcctc ctctggcacc accacctcca cctcttcggc gacttcgtct      540

ccggctcctt ccatcggacc cccggcgtcc tctgggccaa ctctgttccg cccggagccc      600

atcgcttcgg cggcggcggc ggcggccaca gtcacctcta ccggcggcgg cggcggcggc      660

ggcggcagcg gaggcggcgg cggcagcagc ggcaacggag gcggcggtgg cggcggcggc      720

ggtggcagca actgcaaccc caacctggcg gccgcgagca acggcagcgg cggcggcggc      780

ggcggcatca gcgctggcgg cggcgtcgct tccagcaccc ccatcaacgc cagcaccggc      840

agcagcagca gcagcagtag cagcagcagc agcagcagca gtagtagcag cagcagcagt      900

agcagcagca gctgcggccc cctccccggg aaacccgtgt actcaacccc gtccccagtg      960

gaaaacaccc ctcagaataa tgagtgcaaa atggtggatc tgaggggggc caaagtggct     1020

tccttcacgg tggagggctg cgagctgatc tgcctgcccc aggctttcga cctgttcctg     1080

aagcacttgg tggggggctt gcatacggtc tacaccaagc tgaagcggct ggagatcacg     1140

ccggtggtgt gcaatgtgga acaagttcgc atcctgaggg gactgggcgc catccagcca     1200

ggagtgaacc gctgcaaact catctccagg aaggacttcg agaccctcta caatgactgc     1260

accaacgcaa gttctagacc tggaaggcct cctaagagga ctcaaagtgt cacctcccca     1320

gagaactctc acatcatgcc gcattctgtc cctggtctca tgtctcctgg gataattcca     1380

ccaacaggtc tgacagcagc cgctgcagca gctgctgctg ctaccaatgc agctattgct     1440

gaagcaatga aggtgaaaaa aatcaaatta gaagccatga gcaactatca tgccagtaat     1500

aaccaacatg gagcagactc tgaaaacggg gacatgaatt caagtgtcga tgagaccccg     1560

ctttctacac caaccgcaag agacagcctt gacaaactct ctctaactgg gcatggacaa     1620

ccactgcctc caggttttcc atctcctttt ctgtttcctg atggactgtc ttccatcgag     1680

actcttctga ctaacataca ggggctgttg aaagttgcca tagataatgc cagagctcaa     1740

gagaaacagg tccaactgga aaaaactgag ctgaagatgg attttttaag ggaaagagaa     1800

ctaagggaaa cacttgagaa gcagttggct atggaacaaa agaatagagc catagttcaa     1860

aagaggctaa agaaggagaa gaaggcaaag agaaaattgc aggaagcact tgagtttgag     1920

acgaaacggc gtgaacaagc agaacagacg ctaaaacagg cagcttcaac agatagtctc     1980

agggtcttaa atgactctct gaccccagag atagaggctg accgcagtgg cggcagaaca     2040

gatgctgaaa ggacaataca agatggaaga ctgtatttga aaactactgt catgtactga     2100

atctttcctg ttgaagaaat ccatgttata gaaaagaact ttgcagtcag acattcgtca     2160

tgggaaagtt cagaaaaaaa taaagtcctt ttaagggaac ttcctgaatt ttgtgtatta     2220

atgttcttta aaagtttaag tattctacaa aaaaaaaaaa agttttctcc attgattttc     2280

acctgtggtt cataccagag acctgagaat gtttgtaaat gtacaagtat caaagttctt     2340

acagttaatt actgcaactt gctgctggac aattgtatac agagttaaag gcaggtctga     2400

ataagaccta gctttgtttt tttctaatgg aatgaaccat tttcctcttc tgaaaattct     2460

gtatctgagc acatcaagag actcttgtag cagtggttac ccagacttac agaattatgt     2520

cctccagaaa ccagcaagaa cacttggaat gaacgaatga acttgtaggg ggcatagagg     2580

attcttgaaa aaaaaaaatg caagagtgat tttctgttac attcaatttc aaactctcta     2640

attgtgggtt ttctcctgaa gaattttttt tcacatactt tccaaaagac caacaaatgg     2700

atgttgacaa caacccaatg aaataacatt ttgcatatct gaaaagaagc attgaatata     2760

agccaaaagc tttcactgaa ggtttttttt tcttaaaaat aaaaaaaaat atataagtgt     2820

aacatgtttt cattccaaac tggtagtggt atatagaatt aaagataata atgttgcttc     2880

ttattcaaac tgttggtcat atgtacagta tataaacata aaacacacaa ggaaggtatt     2940

atgtatgcag tagtatacta gagtttagga aaatgaaaat tttagaaaat atgttttgtc     3000

accctgttgg tcagaaagat gtctttctgg ttttaacgca tgcaggcatg taaatatttg     3060

tctggagtca cagtattaat gaatgagatc ttaagcatct ggtgacatca gaactctgtg     3120

tcagccactt ttatttgtat attgaaccct agctagtgcc ccaagctgca ctattgggaa     3180

tggattgtgg ctgaacagca aatcaaaaca ccagaaatat ttttatatgt taacgtcata     3240

ttatgttaat gttgctgaaa acaaaaccta acaaaccttg atgtaccagt ccaataccat     3300

gtagcgctga gtgataaagt taaaatgtgc tgtgcttccc acccttgtca gagggaaggg     3360

tggctatgtg ttattttcac tgtctttttg aaagttacag tatgtgtttt cactttcgtg     3420

cagataactg gaagtaaagc ggcaaacagt gcttattaca tgctaaagtt accttctctt     3480

tgttttttgc atatctggaa ttacaccttt aaagactgat atgaatcagt acggtcacta     3540

tacattttat gatttttctg tcatcttaaa attgtatgat cgtaacatta tttattacca     3600

caaaacagca aaatcttcaa tgtctaagaa aactagctta aaatgtttaa atatagttct     3660

gattgggtat taattacttg attaagaaaa aattaacatt atagatactc tggcattacg     3720

cttctatacc ttttaggtct tccttgcaat actggaacat aattcttttg tgtagctcac     3780

tattagccag ctaagttcat ctttttaata ccataaaaag gttatatgta cagttcctat     3840

tttagcttgc ttacaaaggg agcattattt ttatttaaag tattgctagt aaatgatttg     3900

tagaaacttg gttttctaag catagttctt ccataaccac cttttgttgt ttgagcacaa     3960

gggattcttt tcctagttct atgtgtttgt ttccctatat gcagtcttta aaggattaca     4020

acacttaaaa ttgaatggac ttgtgtcaag ctttttgcat catacatttt ttgaaagatt     4080

tttaaaaaag cctacaactt acatatgtag tagaatcagc cattgctctg ctcctggcat     4140

agagtcacct gtttgttatg tggattaaat agttttaaaa tacatatttg aagacctttg     4200

agaatgcttt agtgtttgat ttgaaataaa aggaaatttt agcaaggatt aaagaaaaaa     4260

gctatcagct gtatgttaag agagactctt actaacatgt tgtaaatatt acaattcatg     4320

aaatgttatt gtaagtctgt aacttaattt tttccctgtt ttagttatac aggttggttt     4380

ggaaatttgt gttttggcat aaacaagtaa aatgtgccca ttttatggtt tccatgcttt     4440

tgtaatccta aaaatattaa tgtctagttg ttctatatta taaccacatt tgcgctctat     4500

gcaagccctt ggaacagaac atactcatct tcatgtagga cctatgaaaa ttgtctattt     4560

ttatctatat atttaaagtt ttctaaaaat gataaaaggt tattacgaat tttgttgtac     4620

aaaatctgta caaaaatctg tttttacatc ataatgcaag aattggaaat ttttctatgg     4680

tagcctagtt atttgagcct ggtttcaatg tgagaaccac gtttactgtt attgtattta     4740

attttctttt ccttttcaac aatctcctaa taaaactgtc tgaaatctca aaaaaa         4796


<210>  1732
<211>  5240
<212>  DNA
<213>  homo sapiens

<400>  1732
atctttgatc aatgtacttg ccagggagag cccaagtcct tcaaacctcc tccttttcac       60

cttcatcctt aactttgtgc tagagcgaga cccacacaac aacagccgac cctccccgcc      120

ccacccccac ccccaaacca gccctcgatc ccagcccccg gagaggactc gcatttcgac      180

ttgcgggaca cttttgtgcg ttcctctcca gagcgcctct cgtgctcgcc cctcttgcgc      240

tcgctcttta ttaccttcac ctccttttct cccccttctc tccctttctc cttctcgttc      300

tctcccggag ttgttgttgc ccccctcgct ccttctcccc ccttttttcc ccttcccctc      360

ccgggggtgt gtggcaactt ttcctctcgc ttctcctccg tctgtttccc cttatatgtg      420

accatggcag tgccggcggc tttgatccct ccgacccagc tggtcccccc tcaaccccca      480

atctccacgt ctgcttcctc ctctggcacc accacctcca cctcttcggc gacttcgtct      540

ccggctcctt ccatcggacc cccggcgtcc tctgggccaa ctctgttccg cccggagccc      600

atcgcttcgg cggcggcggc ggcggccaca gtcacctcta ccggcggcgg cggcggcggc      660

ggcggcagcg gaggcggcgg cggcagcagc ggcaacggag gcggcggtgg cggcggcggc      720

ggtggcagca actgcaaccc caacctggcg gccgcgagca acggcagcgg cggcggcggc      780

ggcggcatca gcgctggcgg cggcgtcgct tccagcaccc ccatcaacgc cagcaccggc      840

agcagcagca gcagcagtag cagcagcagc agcagcagca gtagtagcag cagcagcagt      900

agcagcagca gctgcggccc cctccccggg aaacccgtgt actcaacccc gtccccagtg      960

gaaaacaccc ctcagaataa tgagtgcaaa atggtggatc tgaggggggc caaagtggct     1020

tccttcacgg tggagggctg cgagctgatc tgcctgcccc aggctttcga cctgttcctg     1080

aagcacttgg tggggggctt gcatacggtc tacaccaagc tgaagcggct ggagatcacg     1140

ccggtggtgt gcaatgtgga acaagttcgc atcctgaggg gactgggcgc catccagcca     1200

ggagtgaacc gctgcaaact catctccagg aaggacttcg agaccctcta caatgactgc     1260

accaacgcaa gttctagacc tggaaggcct cctaagagga ctcaaagtgt cacctcccca     1320

gagaactctc acatcatgcc gcattctgtc cctggtctca tgtctcctgg gataattcca     1380

ccaacaggtc tgacagcagc cgctgcagca gctgctgctg ctaccaatgc agctattgct     1440

gaagcaatga aggtgaaaaa aatcaaatta gaagccatga gcaactatca tgccagtaat     1500

aaccaacatg gagcagactc tgaaaacggg gacatgaatt caagtgtcgg actggaactt     1560

ccttttatga tgatgcccca ccctctaatt cctgtcagcc tacctccagc atctgtcacc     1620

atggcaatga gccagatgaa ccacctcagc accattgcaa atatggcagc agcagcacaa     1680

gttcagagtc ccccatccag agttgagaca tcagttatta aggagcgtgt tcctgatagc     1740

ccctcacctg ccccctctct ggaggagggg agaaggcctg gcagtcaccc atcatcacat     1800

cgcagcagca gcgtgtccag ctcccctgct cggactgaga gctcttctga cagaatcccg     1860

gtccatcaga atgggttgtc catgaaccag atgctgatgg gcttatcacc aaatgtactt     1920

cctgggccca aagagggaga tttggccggt catgacatgg gacatgagtc aaaaaggatg     1980

catattgaaa aagatgagac cccgctttct acaccaaccg caagagacag ccttgacaaa     2040

ctctctctaa ctgggcatgg acaaccactg cctccaggtt ttccatctcc ttttctgttt     2100

cctgatggac tgtcttccat cgagactctt ctgactaaca tacaggggct gttgaaagtt     2160

gccatagata atgccagagc tcaagagaaa caggtccaac tggaaaaaac tgagctgaag     2220

atggattttt taagggaaag agaactaagg gaaacacttg agaagcagtt ggctatggaa     2280

caaaagaata gagccatagt tcaaaagagg ctaaagaagg agaagaaggc aaagagaaaa     2340

ttgcaggaag cacttgagtt tgagacgaaa cggcgtgaac aagcagaaca gacgctaaaa     2400

caggcagctt caacagatag tctcagggtc ttaaatgact ctctgacccc agagatagag     2460

gctgaccgca gtggcggcag aacagatgct gaaaggacaa tacaagatgg aagactgtat     2520

ttgaaaacta ctgtcatgta ctgaatcttt cctgttgaag aaatccatgt tatagaaaag     2580

aactttgcag tcagacattc gtcatgggaa agttcagaaa aaaataaagt ccttttaagg     2640

gaacttcctg aattttgtgt attaatgttc tttaaaagtt taagtattct acaaaaaaaa     2700

aaaaagtttt ctccattgat tttcacctgt ggttcatacc agagacctga gaatgtttgt     2760

aaatgtacaa gtatcaaagt tcttacagtt aattactgca acttgctgct ggacaattgt     2820

atacagagtt aaaggcaggt ctgaataaga cctagctttg tttttttcta atggaatgaa     2880

ccattttcct cttctgaaaa ttctgtatct gagcacatca agagactctt gtagcagtgg     2940

ttacccagac ttacagaatt atgtcctcca gaaaccagca agaacacttg gaatgaacga     3000

atgaacttgt agggggcata gaggattctt gaaaaaaaaa aatgcaagag tgattttctg     3060

ttacattcaa tttcaaactc tctaattgtg ggttttctcc tgaagaattt tttttcacat     3120

actttccaaa agaccaacaa atggatgttg acaacaaccc aatgaaataa cattttgcat     3180

atctgaaaag aagcattgaa tataagccaa aagctttcac tgaaggtttt tttttcttaa     3240

aaataaaaaa aaatatataa gtgtaacatg ttttcattcc aaactggtag tggtatatag     3300

aattaaagat aataatgttg cttcttattc aaactgttgg tcatatgtac agtatataaa     3360

cataaaacac acaaggaagg tattatgtat gcagtagtat actagagttt aggaaaatga     3420

aaattttaga aaatatgttt tgtcaccctg ttggtcagaa agatgtcttt ctggttttaa     3480

cgcatgcagg catgtaaata tttgtctgga gtcacagtat taatgaatga gatcttaagc     3540

atctggtgac atcagaactc tgtgtcagcc acttttattt gtatattgaa ccctagctag     3600

tgccccaagc tgcactattg ggaatggatt gtggctgaac agcaaatcaa aacaccagaa     3660

atatttttat atgttaacgt catattatgt taatgttgct gaaaacaaaa cctaacaaac     3720

cttgatgtac cagtccaata ccatgtagcg ctgagtgata aagttaaaat gtgctgtgct     3780

tcccaccctt gtcagaggga agggtggcta tgtgttattt tcactgtctt tttgaaagtt     3840

acagtatgtg ttttcacttt cgtgcagata actggaagta aagcggcaaa cagtgcttat     3900

tacatgctaa agttaccttc tctttgtttt ttgcatatct ggaattacac ctttaaagac     3960

tgatatgaat cagtacggtc actatacatt ttatgatttt tctgtcatct taaaattgta     4020

tgatcgtaac attatttatt accacaaaac agcaaaatct tcaatgtcta agaaaactag     4080

cttaaaatgt ttaaatatag ttctgattgg gtattaatta cttgattaag aaaaaattaa     4140

cattatagat actctggcat tacgcttcta taccttttag gtcttccttg caatactgga     4200

acataattct tttgtgtagc tcactattag ccagctaagt tcatcttttt aataccataa     4260

aaaggttata tgtacagttc ctattttagc ttgcttacaa agggagcatt atttttattt     4320

aaagtattgc tagtaaatga tttgtagaaa cttggttttc taagcatagt tcttccataa     4380

ccaccttttg ttgtttgagc acaagggatt cttttcctag ttctatgtgt ttgtttccct     4440

atatgcagtc tttaaaggat tacaacactt aaaattgaat ggacttgtgt caagcttttt     4500

gcatcataca ttttttgaaa gatttttaaa aaagcctaca acttacatat gtagtagaat     4560

cagccattgc tctgctcctg gcatagagtc acctgtttgt tatgtggatt aaatagtttt     4620

aaaatacata tttgaagacc tttgagaatg ctttagtgtt tgatttgaaa taaaaggaaa     4680

ttttagcaag gattaaagaa aaaagctatc agctgtatgt taagagagac tcttactaac     4740

atgttgtaaa tattacaatt catgaaatgt tattgtaagt ctgtaactta attttttccc     4800

tgttttagtt atacaggttg gtttggaaat ttgtgttttg gcataaacaa gtaaaatgtg     4860

cccattttat ggtttccatg cttttgtaat cctaaaaata ttaatgtcta gttgttctat     4920

attataacca catttgcgct ctatgcaagc ccttggaaca gaacatactc atcttcatgt     4980

aggacctatg aaaattgtct atttttatct atatatttaa agttttctaa aaatgataaa     5040

aggttattac gaattttgtt gtacaaaatc tgtacaaaaa tctgttttta catcataatg     5100

caagaattgg aaatttttct atggtagcct agttatttga gcctggtttc aatgtgagaa     5160

ccacgtttac tgttattgta tttaattttc ttttcctttt caacaatctc ctaataaaac     5220

tgtctgaaat ctcaaaaaaa                                                 5240


<210>  1733
<211>  2182
<212>  DNA
<213>  homo sapiens

<400>  1733
cggaccctcc cgcggccgac tggaggcccg gagcaggggc ggagtttccg gcggcagcgc       60

cactcgggcg tcgggtgacg ctaggcggac ggaccatcat gtgacacgga agtagctccg      120

aacaggaaga ggacgaaaaa aataaccgtc cgcgacgccg agacaaaccg gacccgcaac      180

caccatgaac agcaaaggtc aatatccaac acagccaacc taccctgtgc agcctcctgg      240

gaatccagta taccctcaga ccttgcatct tcctcaggct ccaccctata ccgatgctcc      300

acctgcctac tcagagctct atcgtccgag ctttgtgcac ccaggggctg ccacagtccc      360

caccatgtca gccgcatttc ctggagcctc tctgtatctt cccatggccc agtctgtggc      420

tgttgggcct ttaggttcca caatccccat ggcttattat ccagtcggtc ccatctatcc      480

acctggctcc acagtgctgg tggaaggagg gtatgatgca ggtgccagat ttggagctgg      540

ggctactgct ggcaacattc ctcctccacc tcctggatgc cctcccaatg ctgctcagct      600

tgcagtcatg cagggagcca acgtcctcgt aactcagcgg aaggggaact tcttcatggg      660

tggttcagat ggtggctaca ccatctggtg aggaaccaag gccacctctg tgccgggaaa      720

gacatcacat accttcagca cttctcacaa tgtaactgct ttagtcatat taacctgaag      780

ttgcagttta gacacatgtt gttggggtgt ctttctggtg cccaaacttt caggcacttt      840

tcaaatttaa taaggaacca tgtaatggta gcagtacctc cctaaagcat tttgaggtag      900

gggaggtatc cattcataaa atgaatgtgg gtgaagccgc cctaaggatt ttcctttaat      960

ttctctggag taatactgta ccatactggt ctttgctttt agtaataaaa catcaaatta     1020

ggtttggagg gaactttgat cttcctaaga attaaagttg ccaaattatt ctgattggtc     1080

tttaatctcc tttaagtctt tgatatatat tacttgttat aaatggaacg cattagttgt     1140

ctgccttttc ctttccatcc cttgccccac ccatcccatc tccaacccta gtcttccatt     1200

tcctcccgcc agtctccatt gaatcaatgg tgcaggacag aaagccagtc agactaattt     1260

ccttctttcc tcgcacttct ccccactcgt catcttttaa ctagtgtttc acaaggatcc     1320

tctgaaaccc tctctgtgcc ccaagtacag atgccattac ttctgctttc gtatctcctc     1380

aggcaaaagt ggagggtgcc ttatgggccc tcctcatagg ttgtctctgc atacacgaac     1440

ctaacccaaa tttgctttgg tgccagaaaa actgagctat gtttgaacaa agatgtcgtg     1500

caaactgtac tgtgaacaac agttggttta aaatatgagg ggcaaggagg aggatgcatt     1560

tcaaaagctt gattgatgtg ttcagagcta aattaagagg agttttcaga tcaaaaactg     1620

gttaccattt tttgtcagag tgtctgatgc ggccactcat tcggctcccc agaattccta     1680

gactgggtta atagggtcat attgtgaatg tctcactaca aaatgacttg agtccagtga     1740

aatctcatta gggtttaaga atatttcagg gatccttaat gttttgattt ttgttttctg     1800

aaattggatt ttattttatt ttatcttata atttcagttc atctaaattg tgtgttctgt     1860

acatgtgatg tttgactgta ccattgactg ttatggaagt tcagcgttgt atgtctctct     1920

ctacactgtg gtgcacttaa cttgtggaat ttttatacta aaaatgtaga ataaagacta     1980

ttttgaagat ttgaataaag tgatgaagtt gcattacacc tcactgcaag gattctttac     2040

ttagcttgtt tttagatttc ttctatatat attttattta tatcccatct agaattcagc     2100

taggtgctgc tgctgctctg tttcctttga tgacgctttg aaataaaggc aggagtacaa     2160

gcctaaaaaa aaaaaaaaaa aa                                              2182


<210>  1734
<211>  3707
<212>  DNA
<213>  homo sapiens

<400>  1734
ggcatctctc gcgtgctctt gcttgcgcac taatttgtcc tccaccgcct cccgttcagg       60

ccggctctcc tgcggggcgg ggaaaggggt gggaagaggc tgggagctgc ggccgctgtg      120

ccagggtgac cggtagagtt gtagccgagg tggcggcgcg gggcggggcg ggcggagaga      180

gaaggaagga ggtggttgtg caggatggcg acggcggcct acgagcagct gaagctgcat      240

atcacacctg aaaaatttta tgtggaagct tgtgatgatg gagcagatga cgtacttacc      300

attgaccgtg tgtccacaga ggttaccctt gcagtcaaga aagatgttcc tccttcagct      360

gtcacaagac caatatttgg tatactgggc acaatccatc tggtggcagg taattatctt      420

atagtcatta ccaaaaagat aaaagtaggt gaatttttca gtcatgtagt ctggaaagca      480

acagattttg atgtcctttc ttataagaag acaatgttgc acttaactga tattcagtta      540

caagataata aaaccttcct agcgatgcta aaccatgtct tgaatgtgga tggattttac      600

ttttcaacaa catatgattt gacccatact ttgcagcggc tatccaacac tagtcctgaa      660

ttccaagaaa tgagtctctt ggaaagggca gatcagcggt ttgtatggaa tggtcatctt      720

ctaagagaac tttctgcaca gccagaggtt catcggtttg cccttccagt gttacatggc      780

tttattacca tgcattcatg ttctattaat ggaaaatact ttgattggat tctcatctcg      840

aggaggagct gtttcagagc tggtgtgcgc tattatgtaa gaggaattga ttcggaaggc      900

catgcagcta actttgtaga aacagaacaa attgtgcact acaatgggag caaagcttcg      960

tttgtacaga ctcgaggatc aatacctgtt ttctggtccc aaagaccaaa cctcaagtac     1020

aaaccactgc cacagatcag caaagtagca aatcacatgg acggtttcca aaggcatttt     1080

gattcccaag taattattta tggaaaacaa gttataatca atctgattaa ccagaagggc     1140

tcggagaagc cacttgagca gacatttgca acaatggtgt cttccttggg aagtggaatg     1200

atgagataca ttgcctttga cttccataag gaatgtaaaa atatgagatg ggatcgacta     1260

agtattttat tggatcaggt agcagaaatg caagatgaat taagttattt tctagtggac     1320

tctgctggcc aggtggtggc aaaccaggaa ggcgtgttcc gaagcaattg catggattgt     1380

ctagatagaa ccaatgtgat ccagagtttg ttagctcgtc gttcacttca ggcccaactt     1440

cagagactag gagttttgca tgtgggacaa aagcttgaag aacaagatga atttgagaag     1500

atttacaaaa atgcctgggc tgacaacgca aatgcttgtg ccaagcaata tgcgggaact     1560

ggtgccttga agactgactt taccagaact ggaaagagaa ctcatttggg acttataatg     1620

gatggctgga actcaatgat acgatattat aagaacaact tttccgatgg atttagacaa     1680

gattccatag acttatttct tggaaactat tcagtggatg aattagaatc tcatagtcct     1740

ttaagtgttc caagggactg gaaattcctg gctttgccta ttatcatggt tgttgccttt     1800

tcaatgtgca ttatctgttt gcttatggct ggtgacactt ggacagaaac actggcctat     1860

gtgctcttct ggggagttgc aagcattgga acatttttta tcattcttta caatggcaaa     1920

gattttgtcg atgctcccag actggtccag aaagaaaaga tagactgaat ttgtatttgt     1980

ggaaagcggc ttggcttgga agattccatt gtgcagaact ggagtcttta ctgacccgct     2040

ttccacatca gcccaaggtc tttttaatgc ctttatccaa aagcacatct tgtgctccat     2100

gcaggatgat gacagaattg atctgatgtt actgccttga tggtctcttt actattggga     2160

cagttagatt tataatttga agctattctg taattaaaat ataacctgaa ttcagcttgc     2220

agaatggaag ctgaatctgt tcattgtatt ctattgattg tcaatttaat tagctgttgc     2280

agaataagta atatatttta aaaacctagc tcctttcatt atttaaaaca gcaaaattat     2340

ttttgtagct cagtttcatt attgtcattg tagaagcggt cactattagc aggcatactt     2400

ttccacacat ctttggactt ttcttaaaag ttcagtaata agctaactgt gtttataaaa     2460

tgtaagtctc ttacagacat caagtagttt gatgagacag tctgtgactt catgatagga     2520

aagaggagga tgaggtctgg ggttctttaa agtctctggt gggctgcctc atgactttaa     2580

tcagcttgaa ctgccagtgc accagcagtt taggtgtgat gagagaattc agatatactt     2640

tatcttttta aaaaagtgta aataaaatca aagaatgtaa agtctatctc ttacgctaga     2700

ggtccaaagc tgcctctgtt ttaaagatta tcccaatgtg gaagatgccc atgactggtc     2760

agctacttcc tcctatacat tttggtttct ttgagggtca ctcattgaga cacgcaggcc     2820

tctgagaggg tcttgttcta gatttcatat tgcacttgga gggtaacagc tgctttttca     2880

cgcatggtac tcttgatgtt tttcactctg tcaaggattt tgttggctat caatgaatgt     2940

gtctaaaact tagtgcttcc aggtagttat agtactccaa atcaaggacc aacttaaacg     3000

ttaatttttg tgcaaaaaca aacctgaaaa atatgcttcg gaaactgtgc atagttctaa     3060

ttgtaagtca gattgtatat tcaaattgta attaagagat ttaaatatta gaacggtatg     3120

taaggtagta taattaccac tattttaaat aattcagtta aacactgctg caatatttca     3180

gtgttgtgct tgaaaatatg tacagttttt ttccaatatt aataccttat gttgtcctta     3240

aatatttcta aaagcgcctt tatttcagca ttaccttttt ttcatcacta tcttttataa     3300

aacattaata taagtcgtta cttttagaaa ctaaaggaaa taatagctgg aaaaccctct     3360

gtagtttaaa atcagtcatt aaactcacaa tagggtaagt aaatatagcc acctgttaac     3420

atgtaaataa gcataatttg ttccaaagat ggaatattga aacttagttc atgtctgctg     3480

taaaatatta tttaaatgct gctgggcatt tcacttaaag aacttaatgt caacagctac     3540

aacaaagacc aaatctgaac tgctaatgtg gctgctttgt agggaatgga ctaatatcag     3600

tgtgttagat cttaaggtat cagtatttca gaatcctgcg acgattttat ttctaaattc     3660

atgtactgta tgtccataag tgaaaataaa atgtcatatt cttttct                   3707


<210>  1735
<211>  1374
<212>  DNA
<213>  homo sapiens

<400>  1735
atgttgtggg aggtccctga ggccgctgag gtcgttcgtg tctgttgaac ggctgtgggc       60

gtcttgctgc cttgggtagg gggttaaaat cgttcttgag aggaacgtct ctgtgcgaag      120

agataatgag tttagctctg agaagtgagc ttgtagtgga caaaacaaag aggaaaaaaa      180

gaagagaact gtctgaggaa cagaaacaag aaattaaaga tgcttttgaa ctatttgata      240

cagacaaaga tgaagcaata gattatcatg aattaaaggt ggcaatgaga gccttggggt      300

ttgatgtaaa aaaagctgat gtactgaaga ttcttaaaga ttatgacaga gaagccacag      360

ggaaaatcac ctttgaagat tttaatgaag ttgtgacaga ctggatattg gaaagagatc      420

cccatgaaga aatactcaag gcatttaaac tatttgatga tgatgattca ggtaaaataa      480

gcttgaggaa tttgcgacgt gttgctagag aattgggtga aaacatgagt gatgaagaac      540

ttcgagctat gatagaagaa tttgacaaag atggtgatgg agaaataaac caagaggagt      600

tcattgctat tatgactggt gacatttaaa gaattacaag gataaacact aagaatgttg      660

cagttaccat cttatattct atttttgtgc ctggagccat gtgaaaaaaa ccaacttagt      720

tcttttatcc taaaggacca aaaataagca tcttatatat ctgtatttta ctactgttaa      780

gtttctttgt atgaactgtg ttgttagtac tcagatagtt tagctttgta tttataatag      840

agcttttata taaagtttta aaaattgaat gtgtgatatg tgttctttga aggtttttta      900

atttaacatt tatagtcact ttttagtgca cacattttcc agactttcgt taataaaata      960

tttattttat tagaatttta aagtttggta aatttgtttt tattcctagt atctgttaac     1020

cctcaagagt ggatttctta aatcttccct ttataatttt actagtttct gaaacaaaaa     1080

ttgaaataca attagcaata gagtggcaca tttttccatt acctaacatt tcatcaattt     1140

tgacattcta tattttaata caagctgact caatataagc ctaattcctt ttttaagagt     1200

cctgtctttg agtttagaag gaataagtat tgtgcagata gacccattta tccttgtgta     1260

ttatgtttct taacttggta tcattgtaag tatgaaagtt aattttcttc tgaatatttc     1320

cttaaacaaa ttgaatgaat acaatttgaa ttttctaaaa aaaaaaaaaa aaaa           1374


<210>  1736
<211>  10826
<212>  DNA
<213>  homo sapiens

<400>  1736
atgaccaatg ggtctgtgtt ttggaccggc gaagcccaat ggcgcgacag ggaaggcggg       60

cccgagatgg gttagggtgt ccttgcaggg tgtctgagct aaacttcacc aaataatagc      120

tgtttgtatt ttggctgctg caggagccat tttagaaata aatatcttcc ttcaatagat      180

gaaaatgaaa atacagaaaa aagagaagca gttgtcaaat ttaaaagttt tgaatcactc      240

cccaatgtct gatgcctctg tcaattttga ctacaaatct ccatccccat ttgactgcag      300

cactgatcaa gaagagaaaa ttgaagatgt tgctagtcac tgtctgcctc agaaggacct      360

gtatactgct gaagaggaag ctgctaccct ttttcctagg aaaatgacat cccataatgg      420

gatggaggac agtggaggag gaggtactgg agtgaagaag aaacggaaga aaaaggagcc      480

aggagaccaa gagggtgcag caaagggaag caaggacaga gagcccaagc caaagaggaa      540

acgagaaccg aaagagccaa aggaacccag aaaggccaag gagccgaaga aggccaagga      600

gcacaaggag ccgaagcaaa aagatggggc aaagaaggca cggaagcccc gggaggcctc      660

gggcaccaag gaggccaaag agaagaggag ctgcactgac tctgcagcca ggacgaagtc      720

caggaaggcc agcaaggagc aaggaccaac cccagtggag aaaaagaaga aaggaaaaag      780

gaaaagtgaa actacagtgg agagtttaga gctggatcag ggcctgacga acccatctct      840

gcggagtcct gaggagtcca ctgagtctac agacagccag aaacgacgct cgggaaggca      900

agtaaagcgc agaaaataca atgaggacct ggacttcaaa gtggtggatg atgatgggga      960

aacaattgct gttcttggag ctggtcgaac atctgcactc tcagcctcta cactggcctg     1020

gcaggcggag gagcctccag aagatgatgc aaacatcatt gagaagatcc tggcatctaa     1080

gactgtccag gaggttcacc caggagaacc tccgttcgac ttggagctgt tctacgttaa     1140

gtatagaaat ttttcctact tacattgtaa atgggccaca atggaagagc tcgaaaagga     1200

tcctcgcatc gcacagaaga tcaagcgatt taggaataaa caagcccaga tgaagcacat     1260

ttttacggag cctgatgaag acttgttcaa tccagactat gtagaagttg atcgcatctt     1320

ggaggtggcc cacaccaagg atgcagaaac aggggaggag gtaacacatt acctggtgaa     1380

gtggtgctca ctaccatatg aagaaagcac gtgggagcta gaggaagatg tagatcctgc     1440

aaaagttaaa gaatttgaat ctcttcaagt tctccctgaa attaagcatg tggagcggcc     1500

tgcttcagac tcctggcaga aacttgagaa gtctcgcgag tataagaaca gtaaccagct     1560

ccgggagtac cagctggaag ggatgaactg gcttcttttt aactggtata acagaaaaaa     1620

ctgtattttg gctgatgaga tgggcctagg gaaaaccatc cagtccatca cattcctttc     1680

agaaatattt ctgagaggaa tccacggccc ttttctcatt atcgcccctc tctccaccat     1740

cactaactgg gagcgggagt tccggacatg gacagagatg aatgccattg tgtaccacgg     1800

cagccagatc agcaggcaga tgatccagca gtatgaaatg gtgtacagag acgcccaggg     1860

aaaccccctt tcaggagtct tcaagttcca cgtcgtcatc acaacatttg aaatgatcct     1920

agcagactgc ccagagttga agaagattca ctggagctgt gtgataattg atgaagccca     1980

cagactgaag aataggaact gcaaacttct ggagggtcta aagcttatgg ccctggaaca     2040

taaagtgctt ctcactggaa cacccttgca gaactctgtg gaggagctct tcagtttgtt     2100

aaattttctg gagccatcac agtttccttc agagaccgct ttcttggagg aatttggaga     2160

tctgaaaaca gaggagcagg taaagaaact gcagtctatc ctaaaaccaa tgatgcttcg     2220

gcggctgaaa gatgatgtgg aaaagaacct tgctcccaaa caagagacga tcattgaggt     2280

ggaactgacc aatatccaga aaaagtacta ccgtgccatc ctcgagaaga acttttcctt     2340

cctgaccaag ggggcaaatc agcacaacat gcccaatctc atcaacacca tgatggagct     2400

gaggaagtgc tgtaaccatc cctacctgat caatggagca gaggagaaaa ttctagaaga     2460

tttccgaaaa acccacagcc ctgatgcccc tgactttcag ctgcaggcca tgattcaggc     2520

agcaggaaag cttgtgttga ttgataaact actccctaag ctgattgcag gtggccacaa     2580

agtactcatc ttctcccaga tggtgcgctg cctcgacatc ctagaagatt acctcatcca     2640

gagaagatac acctatgagc gaattgatgg gcgagtacgg ggaaacctgc gccaggcagc     2700

catcgaccgg ttctgtaagc cagattcaga ccgctttgtc tttcttctgt gcaccagagc     2760

gggaggcctg gggatcaatc tcacagctgc tgatacctgc atcatatttg attctgactg     2820

gaacccacaa aatgacttgc aggctcaggc ccgatgtcac cgcataggcc agagcaaagc     2880

tgtgaaggtg tatcgcctca tcactcgaaa ttcctacgag cgcgagatgt ttgacaaggc     2940

cagcctaaag ctggggctgg acaaggctgt tcttcaggac atcaaccgaa agggcggcac     3000

caatggggta cagcagctct caaaaatgga ggtggaggac ctactccgga aaggtgctta     3060

tggagcctta atggatgaag aagatgaagg ctccaagttc tgtgaagaag acatagacca     3120

gattctgcag aggcgaacgc acaccatcac catccagtct gaggggaaag ggtccacttt     3180

tgccaaggct agctttgtgg cttcaggaaa cagaacagat atttccttag atgatcctaa     3240

cttttggcag aaatgggcta aaatagctga actagacact gaagcaaaga atgaaaagga     3300

aagcttagtg atcgaccgac ctcgcgtgag aaagcagacc aaacactaca actcgtttga     3360

ggaagacgag ctcatggagt tttcagagtt agacagcgac tcagacgaaa ggcccacgag     3420

atccaggcgc ctcaatgaca aagccaggcg ctacctccga gcggagtgct tccgggtaga     3480

gaagaacctg ctcatctttg gctggggccg gtggaaggac atcctgactc atggccgatt     3540

caagtggcat ctgaacgaga aggacatgga gatgatttgc cgtgccctcc tggtgtactg     3600

tgtcaagcat tataaggggg acgagaagat caagagtttc atttgggaac tgatcacacc     3660

taccaaagat gggcaagccc agaccctcca gaaccactca ggcttatctg ccccagtccc     3720

cagagggagg aaggggaaga agacgaagaa ccagttgcta atcccagagc taaaggatgc     3780

agattggcta gccacctgca accccgaggt ggtcttgcat gatgatggct ataagaaaca     3840

cctcaaacag cactgcaaca aagtactttt gcgagtccgg atgctgtact acctaaaagc     3900

tgaaatactg ggagaagcag ctgagaaagc atttgaagga tctcctgcca gggagctgga     3960

tgtacctctg cctgacatcg actacatgga gatcccagtg gactggtggg atgctgaagc     4020

cgataagtca cttctcattg gcgtgttcaa gcatggttat gaaaggtaca atgccatgcg     4080

agcagaccca gcactttgct tcctggagaa agttgggatg cccgatgaga agtccctttc     4140

tgcagaacag ggtgttacag atgggacctc agacattcct gaaagaggca acacagataa     4200

agaagacaat gctgaggaca aagtagatgg cctccagaaa caaacggaga gttccagtga     4260

tggaggtgat ggcgttttta gcgaaaagaa ggatgacagc cgggcagccc aggatggctc     4320

cgacccagac aaatcgccct ggccagtttc ctccgccctc acagctcgtc tcagacgtct     4380

ggtcactgtt taccagcgct gcaaccgcaa ggaactgtgc cggcctgaaa ttctgggacc     4440

aggtaaccaa ggatattggg ttcaggaaga gatgttcagg agaacctcag aaatggacct     4500

catcaacaag gaagcccaaa agaggtggac taggagagaa caagcagact tctatagaac     4560

agtgtcttcc tttggtgttg tttacgatca agaaaagaaa acctttgact ggacacagtt     4620

ccgcatcatt tcccgtttgg acaagaagtc ggatgagagc ctggaacagt atttttatag     4680

ttttgtggcc atgtgccgga atgtctgtcg tctacccaca tggaaagatg gcggtccccc     4740

agataccacc atctacgttg aacccatcac tgaggaacgt gctgcaagaa ctctgtaccg     4800

cattgaactg ttacggaaag tccgagagca agtgctcaag tgccctcagc tgcatgaacg     4860

cctccagctg tgcaggccca gcctctacct cccagtctgg tgggagtgtg ggaagcatga     4920

tcgagacctg ctcatcggca ctgccaaaca tgggctgaac cgcactgact gttacatcat     4980

gaacgacccc cagctgtcct tcctggatgc ctatagaaac tatgcccagc ataaaagatc     5040

tggcacccag gcaccaggaa atctctgttg cctttaccag accaactcca agttatatga     5100

atctcttaca tattctcaaa tgagtaggac ttcagagtcc cttgaaaatg aacctgaaaa     5160

tctagtgaga gtagaaagca gagatgatca tctcagcctg cctgatgtga catgtgaaaa     5220

ctttatttct aaagttcagg atgtcatttc catcaaccat gatgaaagtc tgctgcctga     5280

gtccttagag agcatgatgt atggtaagaa ggtgctcagc caagaaccaa gctcttttca     5340

ggagagccca agtaccaata ctgaatctag aaaagatgtt attaccatct caataagcaa     5400

agatgggaac tgccagtctg gtggccctga ggcagaaata gcttctggcc ctacttttat     5460

gggtagctta gaagcaggag gagtagctca agcaaacatc aaaaatggaa aacatttgtt     5520

gatgtctatt tcaaaggaag gggagctctg ctgcagtgag gcaggacaga gacctgaaaa     5580

cattggccag ctggaagcca agtgtttagc ttccccttcc ttgaatccag gaaatgaaag     5640

tgggtttgta gatatgtgca gtcttagtgt ctgtgactcc aaaagaaacc tgtcatcaga     5700

tcagcaatta attgatttat tggaaaacaa aagcttagaa agtaaattga ttttgagtca     5760

gaaccacagt gatgaggagg aagaagagga ggaaaacgag gaggaaaact tagccatggc     5820

agtaggcatg ggggaaaggc cagaggtatt gcatctcacg gagcccacta ctaacatctc     5880

aagggaaaag aaccaaggct tccaagatga aaccaagaaa ggaagcttag aggtggcaaa     5940

ccagactcct gggctacaga gggctttccc cgctccagca gcctgtcagt gccactgcaa     6000

acacatggag aggtggatgc atggcctcga gaatgatgaa tttgaaatcg agaaacccaa     6060

ggcttatatc ccagatctgt tcaaaagtaa aaccaatact atcgccatgg agggtgaacc     6120

cactgctatt ccatcacagc cgtttaaagt gaagcatgag cttttaaaag aaccttggaa     6180

agaaagtgca gaggggcaaa acgttttccc cacatatcct cttgaaggaa gtgagctcaa     6240

atcagaagac atggattttg agaataaaga tgattatgat agagacggaa actgccatag     6300

tcaagattat ccagggaagt actctgaaga ggagagcaag agctcaacat cgggcatcac     6360

aggagacatt ggggatgagc tacaggaggc tcgagctccc actattgctc agctgctaca     6420

ggagaaaact ctctattcct tctctgagtg gccaaaggac cgcgtgataa ttaaccgcct     6480

agataatatc tgccacgtgg tgttaaaggg gaagtggccc tctagccagc agtatgagcc     6540

ctcaggcaca ctgcccaccc cggtattaac cagcagtgct ggttctcgaa ccagcctctc     6600

agagccggaa gcagcagaac acagcttcag caacggcgca gcattggcgg cccagatcca     6660

caaggagagc ttcttagctc cagtattcac aaaggatgaa caaaagcaca ggcgtcccta     6720

tgagtttgag gtggagaggg atgcaaaggc tcggggcctg gagcagttct ctgccaccca     6780

cgggcacacc cctatcatcc tcaatggctg gcatggggag tcagctatgg acctctcctg     6840

ctcatcagag gggtccccag gagccacatc ccctttccca gtgagcgcca gcacccctaa     6900

gattggggct atcagttcac ttcagggagc ccttggcatg gacttgtctg ggattctgca     6960

agctggcctg atccatcctg tgactggaca gattgtcaat ggaagcctca gaagagatga     7020

tgcagccacg aggaggcgga gagggaggcg gaaacatgtt gaaggaggga tggacctcat     7080

ctttttgaag gagcagacac ttcaggcggg aatcttggaa gtccatgaag acccagggca     7140

ggccaccttg agcaccacac accctgaggg gccagggcct gccacctcgg ctcctgagcc     7200

agctacggca gccagcagcc aagccgagaa atccattccc agcaagagtc tgcttgactg     7260

gctaaggcag caggctgact actccttaga agttcctggc tttggggcaa atttttcaga     7320

caaaccaaag cagaggaggc cacgctgtaa agaacctgga aaattagatg tcagctccct     7380

gagcggggaa gagagagttc ctgccatccc caaggagcca ggactgaggg ggtttcttcc     7440

agaaaacaag ttcaatcaca ctctggctga gcctattctt cgagatacgg gcccccgcag     7500

gagggggagg cggcctcgga gcgaactcct gaaggctcct tccattgtgg cagactctcc     7560

ctctggaatg gggccactgt tcatgaatgg actgattgct gggatggacc tggtaggact     7620

tcagaacatg agaaatatgc caggcatccc cctcaccggg ctggtggggt ttccagctgg     7680

ctttgccacg atgccaacag gtgaagaggt caaaagtacc ctgagcatgc tgcccatgat     7740

gctgccaggc atggctgctg tgccccagat gtttggtgtt gggggactcc tcagtccacc     7800

catggcaacc acctgcactt ccactgctcc ggcgtctcta tcaagcacaa cgaaaagtgg     7860

tacggcagtg actgaaaaga ctgcggaaga caagccgagt agccatgatg tgaaaacaga     7920

cactttagct gaggacaagc ctggtccagg tccattttct gatcagtctg aacctgcaat     7980

aactactagt agtcctgtgg cttttaaccc atttctcatc ccaggagtat ctcctggact     8040

catttaccca tccatgttcc tctcccctgg tatgggcatg gctctgccag ccatgcagca     8100

ggccagacac tcggaaatag taggtctgga gagccagaag aggaagaaga agaagacaaa     8160

gggggacaac cccaactccc acccagagcc tgctcccagc tgtgaaaggg agcccagcgg     8220

tgatgagaac tgtgccgaac ccagtgcccc tttgcccgca gagagagaac atggggcaca     8280

ggctggggag ggggcactca aagactccaa caacgacacc aattagaact tttttcattt     8340

aagaaattat tgtgacttgt aagtttctta tcccataaag gtttgttact tccctcactt     8400

cacctccata agaacctgtg tttccataag taagattacg tacctgattt cctgtctgag     8460

aactatggta acagatgtta atagttgcag ggtctcacca cttcattaga taagtgttgt     8520

ctacctagtc taggaggcac agaattctca ttctgttatc cagttcattc cagcaatcat     8580

agttaataca gtacttggtg acacgcccta cccccttctc ttccaagttt cccactcact     8640

tgaggaggaa aaatggcaaa agaaagctgt ctagggtttt accattgaag ggtggaagaa     8700

cagagacaaa gaggagctct ttttctgtga gctgggttgc acaggaagaa tgtcacaggg     8760

aaccaaaaag cacagaaaaa ggaagtgctg gtgcatattt ttgagttaaa atatttccct     8820

attttatcat gattactaag tgagtagtat agacagaagt atataactaa tggttgaaaa     8880

tacatatatt catttcttta taaaaaacaa aaaccttacc ggtagtaata taatttcccc     8940

cttggtggtt tttcagacac ctgcagcaag aagaaatact gactgactag gcattatttt     9000

ctatacatcc ctctcaccag tgaaaagatt cctcttgctg cgagaaagct ttacccacca     9060

tgagttattg ctgtcgacgg gggtggggca aggacccgcg ctccgtagag ctacacgctg     9120

cttcacaagc acacggctag cgctctgctc tcacctggtt cgcttacaga tttctctagc     9180

cattaatttg cctctctgtg tttaaagagc accaggaccg aatggatttt cacttcaggc     9240

tttccttcac caagaataag gttctttctg gagcctgcaa gaagacagtt gcccaacact     9300

ttgacacttg ctagtaggtc ctttgatcaa gagtgtctga ggctgtcaaa tgtgtgccac     9360

cctttataat acagctatga aaagttactt ctccattaat ttctccattc tgtttatatc     9420

ttacagttgg acccaaattc caaattatca gttaatcgaa actacattgc aagtcaacat     9480

tattttctct tcttcctcag cttctccatg tttaggaact gagaaagaac ctgcctaagc     9540

agcacttccc catgtccttt caccttcatg ttaacgtccc ttctgatggt ctcactcttc     9600

acaggtagtt cacactctga gacttgaagt aagctcatgg ttcagtactc tgggggcgca     9660

gggctgcgca ggacccttgg aaatgttgca agtgttacta gtaccagttt cactttttgt     9720

tgtcacaatt tactgtattt tttacttttt ctgttacagt tttgctaatt tatcagaagg     9780

tccaaaagtc tgacataact atttcatttt gcattattta tttatgatgc ttttttcatt     9840

gtcttttata catttgggat tataaattat gtaaatgtta aaatgagcat ctcaaagaag     9900

tctgttaaat catgactgaa aaaaatcaat cagatgtatc ttcaaaaagt ggagtcccag     9960

ttttatgaat cagagatata aaccagaaat tctataactg atcatagaag aagaatccag    10020

taattgaaca aatcctattt aatgacatcc ttgtagcata gatggtctat aatgctgacc    10080

acagatttct tagaaatgct gctctctcta tttaactaac attttgttca gttttgcctc    10140

cagtggaagc agaaagggtt ttttcagctg ttaaatccta aaaatcaata taatttattt    10200

atgtaagaaa aataactcaa tcaatatatt tttgaacctt ttaagtacta attttctttt    10260

tatcaagtag aaaaaaaaat gtatttgccc taaatcctta aaatacaaat gctataaaaa    10320

ttcctgtatc ttgaaagcct tactgcaaat gagtattata gacatccagc agagtctggt    10380

tttctttgtt gtcgttgtgt tgttgttgtt ttgtatggaa aagctgcttt ccccgggttc    10440

cacttataac ctccggtagg tcacagggtt caatgtggat ctgacttaaa aacccaccag    10500

catgctcaat cccttgttat ccttatggaa tctgtatgtt aactctctgg gtgttcaggc    10560

ttctatttga ctgctgttgt gaccctgttt gcaaaatgaa tatgacactc tgtggattat    10620

ttgctctgta aggcacaagt gcttcttatg attattttga cgtttccaag agcaaaagcc    10680

aaatttaaac tctcttcagc aaacttgagc cttttcatct aattccatgt cactcacggc    10740

cataactttc cttgaccatt cttcacccca tgtcttacat aataaattgt ggtcttgatc    10800

ctggatttaa aaacaaaaaa aaaaaa                                         10826


<210>  1737
<211>  3227
<212>  DNA
<213>  homo sapiens

<400>  1737
cccactctgc agttgtctcc cgagcgctgg ctgcgccgcc cgagccgctg ggccggggaa       60

gcactggccg ttcgctcccg ggccggctcc gccaggcgct cgcaggcatg cagcccggga      120

gcaggaggcg ctccccgggc cgctgctgag ccggccgggg cggcggggac cagcgccagc      180

ggagcccctc ccaccttgcc ccggggcaga cgagcggcgc cccgacaccc cctcttctcc      240

cgcagccccg ccagcgccac cccccgcggg ccgcaggggc tcatgcagcc gccaagggag      300

aggctagtgg taacaggccg agctggatgg atgggtatgg ggagaggggc aggacgttca      360

gccctgggat tctggccgac cctcgccttc cttctctgca gcttccccgc agccacctcc      420

ccgtgcaaga tcctcaagtg caactctgag ttctggagcg ccacgtcggg cagccacgcc      480

ccagcctcag acgacacccc cgagttctgt gcagccttgc gcagctacgc cctgtgcacg      540

cggcggacgg cccgcacctg ccggggtgac ctggcctacc actcggccgt ccatggcata      600

gaggacctca tgagccagca caactgctcc aaggatggcc ccacctcgca gccacgcctg      660

cgcacgctcc caccggccgg agacagccag gagcgctcgg acagccccga gatctgccat      720

tacgagaaga gctttcacaa gcactcggcc acccccaact acacgcactg tggcctcttc      780

ggggacccac acctcaggac tttcaccgac cgcttccaga cctgcaaggt gcagggcgcc      840

tggccgctca tcgacaataa ttacctgaac gtgcaggtca ccaacacgcc tgtgctgccc      900

ggctcagcgg ccactgccac cagcaagctc accatcatct tcaagaactt ccaggagtgt      960

gtggaccaga aggtgtacca ggctgagatg gacgagctcc cggccgcctt cgtggatggc     1020

tctaagaacg gtggggacaa gcacggggcc aacagcctga agatcactga gaaggtgtca     1080

ggccagcacg tggagatcca ggccaagtac atcggcacca ccatcgtggt gcgccaggtg     1140

ggccgctacc tgacctttgc cgtccgcatg ccagaggaag tggtcaatgc tgtggaggac     1200

tgggacagcc agggtctcta cctctgcctg cggggctgcc ccctcaacca gcagatcgac     1260

ttccaggcct tccacaccaa tgctgagggc accggtgccc gcaggctggc agccgccagc     1320

cctgcaccca cagcccccga gaccttccca tacgagacag ccgtggccaa gtgcaaggag     1380

aagctgccgg tggaggacct gtactaccag gcctgcgtct tcgacctcct caccacgggc     1440

gacgtgaact tcacactggc cgcctactac gcgttggagg atgtcaagat gctccactcc     1500

aacaaagaca aactgcacct gtatgagagg actcgggacc tgccaggcag ggcggctgcg     1560

gggctgcccc tggccccccg gcccctcctg ggcgccctcg tcccgctcct ggccctgctc     1620

cctgtgttct gctagacgcg tagatgtgga gggaggcgcg ggctccgtcc tctcggcttc     1680

cccatgtgtg ggctgggacc gcccacgggg tgcagatctc ctggcgtgtc caccatggcc     1740

ccgcagaacg ccagggaccg cctgctgcca agggctcagg cacggacccc tccccttcta     1800

gtgcacgtga caaggttgtg gtgactggtg ccatgatgtt tgacagtaga gctgtgtgag     1860

agggagagca gctcccctcg ccccgcccct gcagtgtgaa tgtgtgaaac atcccctcag     1920

gctgaagccc cccaccccca ccagagacac actgggaacc gtcagagtca gctccttccc     1980

cctcgcaatg cactgaaagg cccggccgac tgctgctcgc cgatccgtgg ggccccctgt     2040

gcccgccaca cgcacgcaca cactcttaca cgagagcaca ctcgatcccc ctaggccagc     2100

ggggacaccc cagccacaca gggaggcatc cttggggctt ggccccaggc agggcaaccc     2160

cggggcgctg cttggcacct tagcagactg ctggaacctt ttggccagta ggtcgtgccc     2220

gcctggtgcc ttctggcctg tggcctccct gcccatgttc acctggctgc tgtgggtacc     2280

agtgcaggtc ccggttttca ggcacctgct cagctgcccg tctctggcct gggcccctgc     2340

cccttccacc ctgtgcttag aaagtcgaag tgcttggttc taaatgtcta aacagagaag     2400

agatccttga cttctgttcc tctctctcct gcagatgcaa gagctcctgg gcaggggtgc     2460

ctgggcccca gggtgtggca ggagacccag tggatggggc cagctggcct gccctgatcc     2520

tctgcttcct cctcacaacc ccaagagccc ccagcccggt ccatccacgt ctggagtctg     2580

gggagaggag cagggtctta ggactctcag ctctgagcat ccctggcagg gtcttcaacc     2640

tctaatctct tcccttaagc cctgtggcca cacagccagg agagacttgc cgctggctcc     2700

cgcctcattt cagcccaggg tgctcatcca ggggcccaga acagtcccac ctgtgctgct     2760

gtgcccacag cacaaagcca ggcttcactc ccaaaagtgc agccaggccc tggagggtga     2820

tcctgccagc agccctacag ctccacaccc tacccaccca tcggcagccc ctctgctgtt     2880

ccccagggac ctctcataca ctggccagga ggctgcagaa cgtgtgtctc cccctccctc     2940

caagaggtcc tgctccctct gccagaaccg tgtgtgggcg ggtgggaggg cgctcggggc     3000

ccggcccctc cctctccctg ctggttttag ttggtcccta tgttggaagt aaaaagtgaa     3060

gcactttatt ttggttgtgt ttgctcacgt tctgcttgga agtggggacc cctcactgcg     3120

tccacgtgtc tgcgacctgt gtggagtgtc accgcgtgta catactgtaa attatttatt     3180

aatggctaaa tgcaagtaaa gtttggtttt tttgttattt tctttta                   3227


<210>  1738
<211>  879
<212>  DNA
<213>  homo sapiens

<400>  1738
ctcctcacag aagcctggag ctgggcatcc aagaagaagc agcctcattt gttttctggt       60

gtcatcgtag gtggccacct atggcttttg ggaatgtaaa aagggcagct ctctggcatg      120

ttcctgactg aggatctcat aacatttaac ttgaggaact tcctcctttt ccagctttgg      180

gagtcaagct tctcacctgg ggcgggtggg ttctgcacca ccctcccacc ctccttcctc      240

cgtgtggacg atagagccac atccagcacc acggacagct cccgggcgcc ttcatctcct      300

cgtcctccag gcagcacaag ccattgtgga atctccacca ggtgtacaga acggtgcctc      360

tgcgtcctgc cactcaggac ctctcaagtc cccgatgtga tggctcctca gcatgatcag      420

gagaaattcc atgatcttgc ttattcctgt cttgggaagt ccttctccat gtctaaccaa      480

gatctatatg gctatagcac cagctctttg gctcttggct tggcatggct aagttgggag      540

accaaaaaga agaatgtact tcatctggtt gggctggatt ccctctgata agccttccca      600

gttgactgaa agatgaggct aggctctagc aagttgaagt caaaccagct ccttcaagaa      660

gctttgagca gaatgaagtg gggaggaccc agcttccagc ccaggaagcc cactgtacct      720

ggagccatct gggataagac tttgacccat gactcccata tccacagcct gtccatccta      780

gcccatccca gtttatcctg tatcatttga gctgggattc ccacatcctc tgagttggaa      840

gtcccatctc aagtcttcaa taaagactct tgaatattg                             879


<210>  1739
<211>  5121
<212>  DNA
<213>  homo sapiens

<400>  1739
agaggatcgg ccgggcgcgg cgggaaggag gctgcgggca gcgaggagcg gctggcgctc       60

gaggcggcgg acggcaccat gtccccgggg agcggggtga agagcgagta catgaagcgc      120

taccaggagc cgcgctggga ggagtacggg ccgtgctacc gcgagctgct gcactaccgc      180

ctaggccgcc ggctgctgga gcaggcgcac gcgccctggc tctgggacga ctggggcccg      240

gccggctcct cggaggactc ggcgtcgtca gagtcgtcgg gcgccggggg ccccgcaccc      300

cggtgcgccc cgccctcgcc cccgccgccc gtagagccgg cgacccagga ggaggcggaa      360

cggcgggcgc gcggggcccc ggaggagcag gacgcggagg ccggggacgc ggaggccgag      420

gacgcggagg acgcggctct gccagcactg ccagtgaaag atgtagaaga taaacctgaa      480

caacaaacca gaacaagaga gactgacaaa tcacccacca gtactgagcc tcgacagcaa      540

ccaagtgcct tatttgctag aggaaacagg aaagcggtca aaagtcccca aagatcatcg      600

agtaaaataa aagaaaacaa gcatccattt gctctttatg gctggggaga aaaacagacc      660

gatacaggaa gccagaagac tcacaacgtc tgtgcgtccg ctcctgtgca cgagattcat      720

gaatcagcat tacgagccaa gaacagaaga caggtggaaa aaaggaaact ggttgctcaa      780

aggcagcgag ctcactctgt ggatgtggag aagaacagaa agatgaaggc ttcctcctca      840

gagaacccgt ggatgacaga atacatgagg tgctattcgg caagagctta aagaaacact      900

tgcgtggaca gcctctttta aaaagtgtaa atgactgaaa ggaaaaacaa aacaaaaacc      960

atcaaaagaa acggacacag gtttaagaaa ccaactgatt atgcaaggtt ttttttaggg     1020

aatttgtaaa agattgtttt attttgatga atattggtca cctacctcgg cagtagggca     1080

gacagttgaa gccatagaca tttggttatt tatgaagata attccctaaa tctttgatat     1140

tcttataagg tttttgtttt aaagcatctt aatcttttaa gatactgaca ccaaatgcct     1200

ttaaatggca acagatgctt acagttcagt attcttttca taagcttagg tagagcctat     1260

tatcatcttg ttctaaataa ctttccagat tccatagcta taagatcatt ccatcctaca     1320

gcataagact cgttttcctt atatgccgtt ttgtttgtga aagaatatca agtcaaaaat     1380

gagtgtcagc actactactg attccatgta taatgaaagt agaactttgc tagttcctga     1440

aaatttttaa cttatttgta tttcagttca gcagcatctt tatgtagatt gtgatattta     1500

agaattatct gggctgggcg agggtctctt tttctctttc agtgatcatc taggcagtta     1560

ttatttaata gtttaatagc tcaagtacat tccaatagac gaagtgcaca caacacaata     1620

tgtgtgtaca gtagtagtaa agtttctttt gagtagtcaa agactcactt tttttattgc     1680

cttttttttt ttttttaaag aatacatact gtggattcag tcccttgtca cacttgacct     1740

tttggcatac acccactgtg gacttttgcc tcttctgtaa tggctggcaa tgacatttca     1800

aacttacaat ctggaattgc acttggtaca ttggcattgc ttgttccact gggatgggga     1860

ccagtgtgaa gatgcctgtt agatagactg cccaccccta ctttctcttt ttctttatag     1920

cacttaacaa taacaaagtc ttgatgatgt acagtattca aactttaggt tgaaatacgt     1980

tactctttga ttcctagcca gtagatctta tctacacttt aatgggagag aatggtggtg     2040

tgtgggtagg cacaaattta tgtaaatagt gctccttctc tttagtatgt ttgctttggg     2100

ggtagaaaaa tggttttaac aaacactggt ttccatcaaa tgaatgatgt cttctccatc     2160

ctgtggagac aagaatctgc tagaaggata tgtgctaagt tccttataag agataatggt     2220

gctctgccta tgccagcttg gcacccgaag atgtgtgagt ggacgtgagg ctgagtatta     2280

ccttagtatt tttctctggg tctttggaaa accatagtca atttttagaa catattgctt     2340

tcattcccca taaactcttc acacatgata actgtttaag ctttgaaaac acatactgaa     2400

gtattgtgag cttaaaaaaa ctttttaaat atttgcatag ttttgaggtg aatttgtttc     2460

cttacagatc tctcctaatc attgagatgt atatttcaaa agaggaaatt ttacatgttg     2520

tccaaaacag ccttgctagt aactggtgaa ttttggtatt aactattatt aaagtcttta     2580

aacgacacag gtacctaaag atcaccttaa tgtggcaatt tgtgatggtg tagctagctg     2640

attgtgaaaa ctgttccttt aaagtcgctt cttgcatgtt cggtgttagt catccagctc     2700

aggcttgtgt tgcagctgac aatctaggaa agacggcctt agagagtggt gcaggcccca     2760

cactgacgga ctgccttaga aacccgactt cctctagact ttgaaccgcc agacttttct     2820

cttgtttaga aaacaaactt atatttaatg tacttactac ttaaaactcc agacagagat     2880

ataatgtaga aggcaaatat tggccaattt tttcctcttt ttaagtggaa gacaaatgaa     2940

cgggattttt aaagtgcttt taaagtgcat gaatggttaa taaatcagta tgaattgtaa     3000

gccttcatct tacatccaag tccttagttg gttagggttt cttttctttc ttttttaaag     3060

agtgtcaatt accttttgaa cctgtgaaaa tttgatagtt gttaacagtc tgatggtcct     3120

aattctttct tttcattcta gaaatgaatg tggttgtaat catgttccta attcttggga     3180

caacctgcaa gacagtgaga cagtttaaaa attacctttc atgttgaaaa agtctgaaac     3240

agagaaccca atgatattta aaataaatgc tacataaaac tctttttaaa attttgattt     3300

taacttaatt aaaacaatgt cataaatatg ctttttgatt ttgttactgc ttttaatatt     3360

aaagtaatag aatattgaag caatattgtc tagcactctg ctggacatta agtccgcggg     3420

aggagaagtg aacaggaatc gattctttgt cttttaactg cccttagtta ggagatgtta     3480

aaatacttgg cacctctggt tatatgtatg ttatgtgtgt tctcccccct aaaatttcta     3540

agcacattta ttcactttta aaatgaatct ttaaaagatt atagttagta gttatagtta     3600

atattctatt tacttggaaa aatgtgaata aatggatctt caaaagattc attttaaaaa     3660

tgaataaatg tataataggc tataggtgat cttacttgcg tattaggtag gaggcacata     3720

tttataccat ttcatatgta atatctttgt cattgtgttt catcgaagat caattgctag     3780

caacttgaag ggtatttata cttgggtcac ttgaactcag ctgactaaat tgtaagaacg     3840

agagcaagca agatggctgt tattggaagc cataacttcc agaagataat tctgcacaat     3900

tcgtaagtta aaaaaaatct gtagggtctt ccactatcct ttttcaggtt gataatgctg     3960

ttctgggcac acactttgta aatggaatgt tatggtacag tcgcctctca gtatccatgg     4020

ggcattggtt ccaggcctcc cttaggatgc caaactccat ggatactcaa accccttcta     4080

taaaatggtg tagtatttgc atatatccta gacacatcct cctgtatgct ttaaatcatc     4140

tctagattac ttaaaatacc taatacaatg taaatgctct gtaaatagtt gttatactat     4200

attgtttagg gaataatgac aaggaaaaaa aagcctgtac atgttcagca caagtgaaac     4260

catccttttt gcccccaaat attttcaatt tgtatttggt tgaatccatg gatgcagaac     4320

tcacggatac agagggccga ctgtactttc tttaaagtgt tcaaaagtat tactagcaaa     4380

gaggaggagg agcaaagcat atatcagaag taaaacaatt tttcttgttg actgctttgg     4440

taaaaaacag tttgatggat agttttacat ttcactggac tagataaaaa atggtgctaa     4500

tatttatgta gcttgatgct atagttgctt tggtatcaaa cttaatacct aacccatata     4560

agatccttat tatataattt tgtgatcagt aaaatgatat tttaaagagt gatcttaaaa     4620

atatgacctg gtcattgcac aacgtttgca tttgaaatga atttttgtac tatagggtgg     4680

atatggagtt attcagtgca agtgtgtgct taatatcaaa ccctatgcaa ggagctatgt     4740

ctagattttt ggtccaaatt tgcctccttc aagcctacta gtgtgagatg gaaaaaaatc     4800

gattgctctt ttaatattat ttccattttg aaattctcga cacttgaatg aaggcagtag     4860

aggcctcttt ttggatttct cttctaataa caaaacttta tttagggaag gtttccctgt     4920

gctatcgtaa gtttgttttg agcactgcat tcactttaaa attctggagg aacaaaggct     4980

gggcacataa tcacaaagcc caggccacac aataattcgg ggttgtattt tctaagaact     5040

atgtattgtt tttagcttat agttaatatt gtatttactt ggaaaaatgt gaataaagtt     5100

aattaacatt acaagctgag a                                               5121


<210>  1740
<211>  5027
<212>  DNA
<213>  homo sapiens

<400>  1740
gccatttttc agctgccggc cgcagcaccc gggctgccgc cgccgcctcg caatccgttg       60

catcggccgc ccccgacgcc tccatccccg cttggggccc gatatccgtg cggccgggac      120

cctcctctct ccagagcccc gattattttt ggcccccggg gcctgtgcgg tgcggaaaaa      180

taaaaagaaa agagagagag ggggctcgga agcgccgggc ggggaggaga gaaggaggag      240

agacttggaa actccgactg caaataataa agaaattgaa aacaatacat taatatacca      300

taacactaaa aagagcagga gcgagagatg agaaagggaa tccagcccgc tctggagcag      360

tacctggtga ccgccggggg tggggagggg gcggctgtcg tcgccgccgc cgctgcagcc      420

tccatggaca aaagggcact gctagccagc cccggcttcg ccgccgccgc cgccgctgcc      480

gccgccccgg gcgcgtacat ccagatcctc accacgaaca cttccaccac ctcctgttcc      540

tcctccctcc aaagcggcgc cgtagccgcc ggccccctcc tccccagtgc ccccggcgcg      600

gagcagaccg ccggcagcct cctctacacc acgccgcacg gaccctccag cagagccggg      660

ctgctgcagc agccaccagc gctgggacgc ggcggcagcg gcggcggcgg cggccctccg      720

gcaaagcgaa ggctggagct aggagaaagc ggtcatcagt acctctcaga tggtttaaaa      780

acccccaagg gcaaaggaag agctgcacta cgaagtccag atagtccaaa aactccaaaa      840

tctccctcag aaaaaacgcg gtatgatacg tctcttggtc tgctcaccaa gaagttcatt      900

cagctcctga gccagtcacc cgatggggta ttggatttga acaaggcagc agaagtgcta      960

aaagtgcaaa agagaaggat ttatgatatc accaacgttc tggaaggcat ccacctcatt     1020

aagaagaagt ctaaaaacaa cgtccaatgg atgggctgca gtctgtctga ggatgggggc     1080

atgctggccc agtgtcaagg cctgtcaaaa gaagtgaccg agctcagtca ggaagagaag     1140

aaattagatg aactgatcca aagctgcacc ctggacctca aactgttaac cgaggattca     1200

gagaatcaaa ggttagctta tgttacatat caagatattc gaaaaattag tggccttaaa     1260

gaccaaactg ttatagttgt gaaagcccct ccagaaacaa gacttgaagt gcctgactca     1320

atagagagcc tacaaataca tttggcaagt acccaagggc ccattgaggt ttacttatgt     1380

ccagaagaga ctgaaacaca cagtccaatg aaaacaaaca accaagacca caatgggaat     1440

atccctaaac ccgcttccaa agacttggct tcaaccaact caggacatag cgattgctca     1500

gtttctatgg gaaacctttc tcctctggcc tccccagcca acctcttaca gcagactgag     1560

gaccaaattc cttccaacct agaaggaccg tttgtgaact tactgcctcc cctgctgcaa     1620

gaggactatc tcctgagcct cggggaggag gaaggcatca gcgatctctt cgatgcttac     1680

gatttggaaa agctcccact ggtggaagac ttcatgtgta gttgattatg cttcgtgtga     1740

actctcctta aaaaccgata tttttttatc atggaaccag aacatctgtc atgcagtgtt     1800

gtcccttcct accttcttcc tccaagagag tatcatgaag taaactacaa acttcagaag     1860

aaagctgaca ttttaatgaa ttttttaaaa aattaataaa caaattgtct aaacgcacag     1920

ttgcaggctc ccttgggaaa gccctgcttt gctccaggct ccaagatctc ctggctaagt     1980

cagcaagtga gaaaatgtgc aatcaggtgt ctctcacccc gaattgtcct tcctccttcc     2040

tccccggatt ggcttgctgt gcctgacgga tgggctgtag aatggggtct ggccacctgg     2100

cctgctggga aacagcaatc ttccttaata gcatttcaag ccgtgccttc tccgcagaat     2160

gcatgtcttt gaggtctgct aatatggaat ggaactgcag caaatgcaaa cttgaagtca     2220

tgcaaaagta tgaaatggat ttcttcagct cttcttagga atatttaaat tactgtcata     2280

attcagttta agctatgaac tgtgtgtccc agtaggaggt caagaaaacc tccacagcct     2340

tctggatgaa gaacctgttt tcaaatatac ttgttgcaga tacagaagac tagtagagtt     2400

ctgccactct aagctgttgt ggattttcct gtctccatga accactccca ttcccccgtc     2460

cccaatgtgt ttgtgagttt ccagttgatt tgtagcaaat gcctacttag ttctttgtgg     2520

attgttctag acttttaatt tttttagctg ccatttaagc attcctgtgg cacccatcac     2580

catttcaatt taattgttta ctttgaagcg gtttttgcaa attcatatta cttaagcaga     2640

gggagagaac ctctactgat cagagcatct aaacctgtgt gatctaaggt ttatcagcct     2700

ctgcaaggag ctttgtccca tcgtgcttcc attcccagga gggggagctt ggagcgagtc     2760

agtcctgggg cttgctgaca tgggtggccc attggaaagg agaaccaggt cagatgatgt     2820

aacagcccca aggagcagca ggcatgggtc cctccatcct tgggcttccc gggcccctgt     2880

gacaggggaa agggctctct tacaccgcac tcagggagac cacttctcag gatggggtca     2940

gatggagaga cctctaggga gaaagacatc cccattgtgt gagtggcatt tccttaagct     3000

ggcaggaaca gggagcagcc ctgtgtcggg ggctggaata gttctggcca gaccccgttc     3060

cccttcctct atgaaggaat aagttggacc aagggaagtc ggggacgtaa aaaatgaagc     3120

aaaacaatgc cagggtgtct cccgctttac tcttcaggaa tggtgtccca agttggaggc     3180

tttgtgtcag ctgcaaatcc taccagttat gtccaagaat ggctttccct cgggcaggtg     3240

gcagcggcca tctcccactg ggaatatggc gtagtatctc cggtccattc cttggatgct     3300

aaggactgcg ggaatgaggg agtcagataa agaacaaacc tcgaaacgaa cagttaaatt     3360

gaaatgctat gtgcctgacc caatggtagg cacatagtag gcactcaact catatgttta     3420

attgaattga aaatatccct taggaaaaaa aaaaaacaca caaaaaacca caagagcccc     3480

agccagttta ctccaggtag atttccacaa tatgcaaagt ggtggtgggg tcaagacaga     3540

tgacaccagc actttaaact ctttgtgtgg gtatgcgtgg gtgtatgttt gggaagaaaa     3600

acaaaggtgc agactatctt cctttttttc ttcttcagcc tccatccctg gcctcctccc     3660

ctcacacaca ctggacttgg tacaaaatgt cggtgtggtc ctagatgaag cattggggtg     3720

ggggagggag agggagcttt gtgttaagtg cctactggaa atgcactgtg gggttttttc     3780

ctgtatggga aaccatttat gccaagcttt tccccatttc ccatatttat ctcatctggt     3840

tagctgcctc tgcttccagc tttgtgtaat tctctttgcc agctgcacaa agctgatttt     3900

ttccaaagtc taaagactga gctcacctgg ctagattgtt gtgtgttttg ttgaattttt     3960

tcataatgta atgccgtatt tattgttttt aaaatgaaag gaatactaat aagtcttaaa     4020

agttccttca tgcataagat ttttttccag ttactgggtt taactggtgt acattaatta     4080

gatgtccata ctgtattttg tttgcattaa gtaattttct ttttgactta gtatccggca     4140

cacaaagtgg gttagtacta cagtatttgc gttactttaa gtactaagta tgcaggtttc     4200

ctggtaccat tgagttgctg ctattaaagc tcacacacga aatggctaaa agttacaagt     4260

gtgcaaatta tgactgcgtg agccttagaa aataaaatgt ataaagggca acacatgagc     4320

tgtcaaacag tgttaggagt gtgtttatat gtacagagtt gtgcatagca atcgttttat     4380

ttaagttgat atgtagtcta ctcacatttt cattatttag caattttgta caaaaatagc     4440

aattaatttg taaacactgc cagaatactt tctagctgct ttgtaatttt ttaagagtgt     4500

tattttgttt ttgtttttct gttctttgtt gtggctcttg ttttcatttt tgttgtacgt     4560

gtagatctgt aaataaaatt gcagtattta aagcttaagc tttcaggaaa aagaaaataa     4620

gaattcagtg tgtgcatgac aactcgtgtg tatgagaagg agggatatga aggaagatgg     4680

cttgcagagt aagtcgggtg gcaattgtca gggtgtggga atttcttttc ctacggggta     4740

cgtgattttg taaaaaggaa gtatttctcc caaaattggg agtaggcaaa ctactaatca     4800

gtttagcttt gtgttgtatg ctagtttaaa aaagaaaata tgtaatataa tgtaaaaaaa     4860

aacaaaaaaa agcttttatg atggattttg taaatagatt tgttacaggg tgacctgttc     4920

tctagctgtg atcttaccac ttcaaatggg tgtaatttga ataaattttg tatggtaaag     4980

gatcaataaa atgatttttt ttaagagtta aaaaaaaaaa aaaaaaa                   5027


<210>  1741
<211>  7329
<212>  DNA
<213>  homo sapiens

<400>  1741
gcagtactcg gagacagcgg acccgtgtca gtgacagctt ccggtttggt ttctccgcct       60

tctgcttggc tagagctatt ggggctcggt ggcggccgca gtggggtgga gggggcaggg      120

cgtggtgagg taaggtgagt gccgtagtgg ggttccctgg agccatggcc tgctccattg      180

tccagttctg ctacttccag gacctccagg ccgcccggga cttcctcttt cctcacctgc      240

gggaggagat cctcagcggc gccttgcgga gggaccccag taaatcaaca gactgggaag      300

atgatggttg gggagcatgg gaagaaaatg aaccacaaga acctgaagaa gaaggaaata      360

cttgcaaaac acaaaaaact tcctggctcc aagattgtgt tttatcctta tctccaacca      420

atgatcttat ggtgatagct cgagagcaaa aagctgtatt tctagtgcca aaatggaaat      480

atagtgataa aggaaaggaa gaaatgcaat ttgctgttgg ctggagtggt tccttaaatg      540

tcgaagaagg ggaatgtgta accagtgctc tatgtatccc actagcaagc caaaagagga      600

gttccactgg gcgtcctgac tggacctgca ttgtggtggg ttttacttca ggttatgtac      660

gcttctacac tgagaatggt gtgctcttgc ttgcacagct tttgaatgag gacccagtac      720

ttcaacttaa atgcagaacc tatgaaatac cacgacatcc cggcgtgact gagcagaatg      780

aagagttgag tatcttatat ccagctgcca ttgtgactat tgatggattt agcctttttc      840

aatctcttcg tgcttgtcga aatcaggtag caaaagctgc agcatcaggc aatgagaaca      900

tacaaccacc accattagct tataagaaat ggggtctaca agatattgac actattattg      960

atcatgctag tgttggtatt atgactctgt ccccctttga tcaaatgaag actgcctcca     1020

atataggtgg atttaatgca gcaattaaaa atagtccacc tgccatgtct cagtatatca     1080

ctgtagggtc caatccattt actggcttct tctatgcttt agagggaagc acacaaccat     1140

tattatccca tgttgcacta gcagttgcaa gtaaactcac ttctgcttta tttaatgctg     1200

ccagtggttg gcttggttgg aaaagtaagc acgaagaaga agctgtccaa aagcaaaagc     1260

cgaaggttga gccagctacc ccattagctg taagatttgg acttccagat tctagacgcc     1320

atggtgaaag catatgtctg tctccatgta acacactggc agcagtaaca gatgatttcg     1380

gcagagttat tttattggat gtagctagag gaattgcaat acgcatgtgg aaagggtacc     1440

gcgacgcaca aattggatgg attcaaactg tagaggacct ccatgaaaga gtgccagaaa     1500

aggcagattt ttcccccttt ggaaattctc agggtccaag tcgagtagct caattccttg     1560

tgatctatgc gccaagaagg ggaattttag aagtgtggag cacacagcag ggacctagag     1620

taggagcttt caatgtgggg aagcactgca ggctgctgta tcctggctat aaaataatgg     1680

gtttaaataa tgttaccagt cagagttggc agccacagac ttatcagatc tgtctggttg     1740

atccagtgtc tggaagtgtg aaaacagtga acgttccctt ccatttagca ctgagtgata     1800

agaagagtga acgagccaag gatatgcacc tagtgaagaa actagcagcc ttactgaaaa     1860

caaaatctcc caatcttgat ttggttgaaa cagaaataaa ggaattaatt cttgatatta     1920

aataccctgc aaccaaaaaa caagctttgg aaagcatttt ggcaagtgaa cgtttaccat     1980

tttcttgcct tagaaacatc actcagactt taatggacac tttaaaaagt caagaacttg     2040

agtctgttga tgaaggattg ctacagtttt gtgccaataa actaaaactg ctgcaactct     2100

atgagtctgt cagtcaatta aattcccttg attttcattt agacacacca ttctctgata     2160

atgacttggc tctgttacta aggcttgatg aaaaagaact gcttaagctc caggcattac     2220

tagagaaata taagcaagag aacaccagga caaatgttcg attttctgat gataaagatg     2280

gtgtgttgcc tgtaaaaaca ttcttggaat atttagaata tgaaaaggat gtgctcaaca     2340

taaagaaaat aagtgaagag gaatatgtgg ctttaggtag tttctttttt tggaagtgtt     2400

tgcatggaga aagctccact gaggatatgt gtcacacttt ggagtcggct ggtcttagcc     2460

ctcagctgtt gttgtctctg ctcctgagtg tttggctttc aaaggaaaag gatattttgg     2520

ataaaccaca gtcaatctgc tgtcttcata ccatgctgtc cctcctgagc aagatgaaag     2580

tggccatcga tgagacctgg gattctcagt ctgtgtcccc atggtggcag cagatgcgca     2640

cagcctgtat tcagtctgag aacaatggag ccgctctgtt gtctgcgcat gttgggcatt     2700

ctgttgctgc acagatatca aacaacatga cagagaaaaa attttcccaa acagttttgg     2760

gtgctgattc agaggccctc actgattcct gggaggcact ttctcttgac actgagtact     2820

ggaaactcct tctgaaacag ctggaggatt gtctcatact tcagactctg cttcacagca     2880

aagggaacac tcagacctcc aaagtgtcat cactgcaggc tgagccactt ccaaggcttt     2940

ctgttaaaaa gttattagaa ggaggaaaag gtggcattgc agacagtgta gccaagtgga     3000

tatttaaaca ggacttcagc cctgaagtat taaaactggc taatgaagaa agagatgcag     3060

aaaacccaga tgaacccaaa gaaggtgtta acagaagttt ccttgaggta tcagagatgg     3120

agatggactt aggagccata ccagacttac tgcatttagc ctatgagcag tttccttgta     3180

gccttgagct cgatgtcttg catgcacatt gctgctggga gtacgttgtt cagtggaata     3240

aagatccaga ggaagcacgt ttttttgtta ggtcaataga acacttgaag caaatattta     3300

atgcacatgt tcaaaatggc attgcactga tgatgtggaa tacgttctta gttaaaagat     3360

tttctgctgc tacatactta atggataagg ttggaaaatc accaaaagat aggttatgcc     3420

gaagggatgt gggaatgagt gacacagcaa tgacatcttt cctcggctcc tgtttggatc     3480

ttcttcagat cttaatggag gcagatgtta gcagggatga aatacaggtg cctgtgctgg     3540

atactgagga tgcgtggctc tccgtggaag gaccaatctc catagtggaa ctggcccttg     3600

aacagaagca catccactac ccactggtgg agcaccactc catcctgtgc tccatcttgt     3660

atgcagtcat gaggttttct ctgaagaccg tgaagccact ttcacttttt gacagtaagg     3720

gaaaaaatgc atttttcaaa gacctaactt caattcagtt attacctagt ggggaaatgg     3780

atccaaattt tatttctgta cgacaacagt tcttattgaa agttgtcagt gcagctgtcc     3840

aggcccaaca ttcagccaca aaggtcaaag atcccacaga agaggccaca cccactcctt     3900

ttgggaaaga ccaagattgg ccagctctag ctgtggattt agcccatcac cttcaagtta     3960

gtgaagatgt tgttagaagg cattatgtgg gggaactata caactatgga gttgaccact     4020

taggagaaga ggccattcta caggttcatg acaaagaggt ccttgcctct cagctgctgg     4080

tgctcacggg gcaaaggctg gctcatgcgc ttctccacac ccagacaaaa gaaggaatgg     4140

agctgcttgc cagacttcca cccacactgt gtacttggct gaaagcaatg gacccccagg     4200

accttcaaaa cactgaagtg ccaattgcaa caacagctaa actagtaaat aaagtaattg     4260

agcttttacc agaaaaacat gggcaatatg gtctagcctt acacctcatt gaagctgtgg     4320

aagccatatc tcttccttct ttatgacact tacctactgg aaatagtcta aaattatgat     4380

tataacatga agtagtgcat ggttatttta catagtaaga cctggaattt tatgggaaaa     4440

gtatgtcttt ttttttcctt ttgtaaaata aataaaagta tatacaactt ttaaaaagtg     4500

caaccctggc taaattccac tcctttggtt aatactgaag ataaaatata aacaaatgtc     4560

aactctgtta taattaatac agatgtttta ctgtttattt ctaattcaaa cacttaagta     4620

gctttattgt taaactttgc tatttaaaat tggttataat ttagattatg ttcttataag     4680

attctatatt tcctatctaa aatgttgttg taattcaatt taaatgtgtt catgtacagt     4740

ccccatcagt agcgtataga acaccccact ctcctttagt aaatgttgag aaaatgcctt     4800

tgttgtcatg ctccaaatcc cacactgggc tgccacctgg gagttctgga taccgaaagg     4860

ttcctttccc agaggttctg ctgttgccat cagaggagga tgaccgtgct tgaggaggaa     4920

gaatgggttc aagatcatca tattcatcag aaggggacac taaatagaac ccttaacctg     4980

ttgtacttgc caaaattgag aatcagagat gtgtaaaatg cagcaaatta attataatgt     5040

aagttaagat ttgctttttg ccaagttgca aagttgtatc cacatcaggt cactgtaaaa     5100

atgtattatc ttgtaaaact tatgtaaaaa aaaaaaaaaa aaaaaggcaa agatactaaa     5160

aattttaagt ccgactttat ttttcctaca agtgtttaga aatgcttctg ggatttgcta     5220

atattatctg tccttgggaa cagtattgaa aaaactgctt agtggtatta cagctttagc     5280

aaacctacct cacagctggg atgagaggat aaaatacaac taattttgta ccctatagtg     5340

cctagagcag tccaagtgct aaataaatat ttactgatta aaaccaaact atagctactc     5400

gggaggctgg aggaggatcg cttgagccca ggagtttgag gccattctgg gcaatatagc     5460

aagaccctgt ctcgaaaaaa aaaaaaaaaa gaaaaaacca aactaaccaa aactctgtaa     5520

aagagtgctt tgagctctac aaataccaag tatttattgt ggtatatttt tagaatgtag     5580

ccatacagtg taattatggg tatctgtcat ggatcacaat tattattcat agtaagtcat     5640

tgtgatacag aagtttgttt cttcacttcc ccttaagaag ccaactatag taatcatgca     5700

aagttgagga gtatgtcctt cagggatata aaaagaaaaa caaatctgtt ttttgagcta     5760

aaagagcaca tccaaacaag aatttaactg gctaaaattt agtaattact gttaagtaac     5820

tatcaaactt gaaatcttac aagataaatg gttaagatgt cttgagtatt tgggatgggg     5880

gcctgtgagt ctgattgaga catacatttt acagagtagc agcactggaa agggctagtc     5940

caacctccca gcctctgctt gggtctccgc tgccccagcc acacacatcc tagaattctt     6000

gtaaacatat ctggctctgt gttaacagtc acttgttata tgttttctaa gagattagtt     6060

cttcctgtga tttttccaag tacgctgaaa gtagtagtat gaacttaagg aggctagtca     6120

aagaaacttg gagttatagg tatttttaaa gaataaatcc tcaattccat catcacttgg     6180

cggggagggg gcacttatta agcattttag ataataaaac tggttaagct tactctggta     6240

gaacagacaa tcaaatctgg ggattgctga gaacaataat aagctgaagt atggctcaca     6300

gaatcctaac acaaatcatt aagtctctag ttagatttgt tatcctaaaa tttttcatag     6360

aattttaaaa tctaattctg acttgtatgg ttaagaaaag cagttaaata ttttactact     6420

tatcaagggc ttttaaaata aataaatctg attgatagga agaaaggcaa ataaatacct     6480

atgtagacat tctataataa caaagagcca tagatgataa aggaattaga ttttaatgta     6540

gaatgggtgg tttctgaaac aaaggtatgt ggtactttgt agttattgat gagaagccag     6600

taaccagtag tgttttccta gatatatgcc caccctcaca caactttctt cattaacaaa     6660

cattaaatat gcatttgtat cttattaaat tatattgtat aatgctgaag gaaaacaaaa     6720

agtgttcaaa taatcataac ttctacatta caggttctgt ttagatgcag aactagaggg     6780

gccagggtaa atgtagataa agagatatat agcaccatgc ttcttaatgc ttcatacttt     6840

tgcaaacaga aaaaaaaagt tttactttta ttataaaact tcatctatgg tcaaagtaaa     6900

cactgttaca tttaaattgc tttttaaaaa caattgcgat ctaaaaagtc aaaaatctga     6960

aatttaataa tatgagactt acactgaata taatgttcat ttagaagttg ctgtggtcca     7020

cttcatttat aaggaacaaa tatttttaca gtacactata gcaacagcaa aagccctctc     7080

tcaccctgat aggaatgggt ttgctgggtg tctagaagtt agattcctgc tgaatagaat     7140

tagccatcct taaaagattt taatccaata ctgaactgtt tataaaatgc tttctctatt     7200

gtaatgtact gtaagtagtg aaattctgta tatactgcta ttttctgtct gttcattgtt     7260

gtgaacttct tatgtatatt agtgaaataa attttcagct ttcatgttgt ttcctaaaca     7320

ttcataagt                                                             7329


<210>  1742
<211>  2889
<212>  DNA
<213>  homo sapiens

<400>  1742
aggcccgggg gtcgccgggg ccacgacttc tcggagaccg tcctgcgctc tctggagacg       60

cgctgtccgc gcccagggtg gtgccatgtg gggcgctcgc cgctcgtccg tctcctcatc      120

ctggaacgcc gcttcgctcc tgcagctgct gctggctgcg ctgctggcgg cgggggcgag      180

ggccagcggc gagtactgcc acggctggct ggacgcgcag ggcgtctggc gcatcggctt      240

ccagtgtccc gagcgcttcg acggcggcga cgccaccatc tgctgcggca gctgcgcgtt      300

gcgctactgc tgctccagcg ccgaggcgcg cctggaccag ggcggctgcg acaatgaccg      360

ccagcagggc gctggcgagc ctggccgggc ggacaaagac ggccccgacg gctcggcagt      420

gcccatctac gtgccgttcc tcattgttgg ctccgtgttt gtcgccttta tcatcttggg      480

gtccctggtg gcagcctgtt gctgcagatg tctccggcct aagcaggatc cccagcagag      540

ccgagcccca gggggtaacc gcttgatgga gaccatcccc atgatcccca gtgccagcac      600

ctcccggggg tcgtcctcac gccagtccag cacagctgcc agttccagct ccagcgccaa      660

ctcaggggcc cgggcgcccc caacaaggtc acagaccaac tgttgcttgc cggaagggac      720

catgaacaac gtgtatgtca acatgcccac gaatttctct gtgctgaact gtcagcaggc      780

cacccagatt gtgccacatc aagggcagta tctgcatccc ccatacgtgg ggtacacggt      840

gcagcacgac tctgtgccca tgacagctgt gccacctttc atggacggcc tgcagcctgg      900

ctacaggcag attcagtccc ccttccctca caccaacagt gaacagaaga tgtacccagc      960

ggtgactgta taaccgagag tcactggtgg gttcctttac tgaagggaga cgaaggcagg     1020

ggtggattct cgaggtggaa gtccgcacat gtcggtggta tttatggcac gattcctttg     1080

gatggcttca tttgccccca gactgtatga aaacatctcc gaattagcat ttctggatat     1140

gtttcatcca gggtatcatt gatttatgat ggaaaaccgg cctcagctgg agatgactgt     1200

gatgttgctg atgggtgtat aacaaatgct tgagtccgaa gtgcccttga gatatggttg     1260

acgaaagaat tttataaact gataaattaa ggatttttat tatgttgtta ttattatttc     1320

ttttttgttg ttgactgcac aggatcaaaa tgcctgttat ctccctttta cctgggactt     1380

tttttttttt tttttttttt tttaatcaga cagggtcttg ctctgttgcc caggctggag     1440

tgcagtggtg cgatctcggc tcactgcaac ttcagcctcc tggattcagg caacactcct     1500

gcctcagcct cccacgtggc tgggattaca ggtgcctgcc cccatggcta attttttgta     1560

ttttttgtag agatggggtt tcaccatgtt ggctgggctg gtctcactct cctgacctca     1620

agcaatctgc ctgtctcagc ctcccaaagt gctgggatta caggcgtgag ccaccgcccc     1680

cagcctgagc cttttttttt ttctaatgca tccaaggtta aggggaagac gcaaataaca     1740

ggactattct aaaaggaaac ctgtttgaac tctgtgagat cagtcatcag tctcagtatt     1800

ccacaggcac accttaattt cattgtaaaa agatatatat attttgtcta tttttgtgct     1860

tttgggggcc tattttgtgc ttttttacct tatgtagaga tcttattaca aagtgatttt     1920

ctacattaaa aagagactga aataaattgt atagttactt aactaatgaa gacatttcag     1980

aactctggga tgattttaat cttgaagtag taggtggtat agtcataaaa ccattcatcc     2040

ccttcttgat tgtatcttaa ttttctggct ttaaggtgac atctgagagg taatgcattc     2100

ttttttatat tgaaatcata aactatcacc cgctgcttct ctgagttact tttaattttg     2160

ccttgtggtt atggtttggc gtttccttct gtttggtttt cagagcccca tgtctatata     2220

gtcctgagtg caagtaatta ctatacttgt aaatgaagat cagtatttct gcctagatct     2280

gataaaaaaa ttttcttgtc ttagttataa aaattcaaag aaatgtgtta caaagatact     2340

tagtatagct cctcagccat aacctgagac ttgggatgaa atttaaacca gatacgattt     2400

actttgcaga tcataaggct ttttatactc ttgttatcaa aatggcttat ttttcaggca     2460

ctaaggattg ttaagagaaa agcttttcaa cgaaggattg cctttcttct cccacactgt     2520

tcttgatttc ctctctcttt caggcctcaa caggcactgt attcattgcc aatgttccaa     2580

attatcaaat tcaagtgaat ttatttgtgt gttctttact tatataaaaa aagataactt     2640

taaggatgtg caagtacatt tccaactgct agcacaacca gtattttgta attaaacaaa     2700

tcgctgtatg gtatggtctt ctacacattt atgtctatag atatctatcg atcatctttc     2760

tattctgttt catgactgaa taatgtaaaa ccagtgttgg caattggtat catcaatgat     2820

actcattttt taataaccaa aggcagggga aaatcatttt acttattaat aaatatttta     2880

tgatgtgaa                                                             2889


<210>  1743
<211>  2371
<212>  DNA
<213>  homo sapiens

<400>  1743
gcctcgcctc ggcgccgcgg ccggcatttc tcctcgcagc tcgctgcctc ctctatccct       60

gcctccctct cccccctctg tttttctccc ttccttccct ctccgaccct cttcctctcc      120

ctcccgatcc tttccctcct cctctcatct ttcccctgtc tctccgttct agctcgtccc      180

ccaccccacc ttttcttctt tctcctcctc tccttcctct ccccctctcc tctgtctcct      240

tccaccgtct cccctgcctc cctgtctttc agtccctgtt tttcagcccc gtctccctct      300

cggtttctct cccccaccct ccctccgggt ttcctccccg gtgccctccc tcctctctcc      360

ctcccctccc cctccgcccc tcgcagcccc gccgctcgca gctcccagtc tgcctccccg      420

aaccggcgcc gccgcccgca ctcgccgcag gaccggcccg cccggctccc ggggtgcgcc      480

ctcctcggtc ccgcgccctc cgggctcgca gggacgtctc ctccctcccg gctcgcggcc      540

ccgcccggcc cggcccccgc ccagagcccc agcgcgccga ggatgtgagt cctgctcgcc      600

tctggcggag cagcagccac tcgcgcgcgg agccggagcg cagcgcagcg cagccgcggg      660

cgctctccgg gccgctcgcg cgagtgccgc gctcttgccc tagcggcgtc ccccggcctc      720

tcgccggcgc caccgccgca gcagcccgcg ggccgtcccc ggccggccgc ccccggcccc      780

agcgccgctg accctgtccg ccgcgggcgg ggacgcgggc ggaggaggcg ccgcggcgga      840

gcccccggac gcgaccatgt cggaggtgct gccctacggc gacgagaagc tgagccccta      900

cggcgacggc ggcgacgtgg gccagatctt ctcctgccgc ctgcaggaca ccaacaactt      960

cttcggcgcc gggcagaaca agcggccgcc caagctgggc cagatcggcc ggagcaagcg     1020

ggttgttatt gaagatgata ggattgatga cgtgctgaaa aatatgaccg acaaggcacc     1080

tcctggtgtc taactccccc aaagacaatg agttaaggga gagaataaga acggcggtaa     1140

cagttattgg caaaaagcat gaaaagagaa agcactttga aatttattac tagcttgcta     1200

cccacgatga aatcaacaac ctgtatctgg tatcaggccg ggagacagat gaggcgagag     1260

gaggaggagg aggaggagaa ggctctgggc tcctctgcaa aaataaaaat aaaaaaataa     1320

ataaaatttt aaaaataata aaaattcact atatacacat ataaagaaat aaaaagaagt     1380

ctcagttgca gctatttgtc aaaattaata tccatttctt tttatatacg gtgaatattg     1440

cgcaattata gatctggatt ttgaaccact taatgaagcg gcaacaccag gtgttttgag     1500

gtgttggcat tcttcgctga tttggctgtt cccaatgttt acattattta atcttgcaaa     1560

aatggttctg tgcacttgga tgtgaaatgc tgtccagttt tatttttttt atgttgttat     1620

ccttggatgt acaaaaaatt cagaaaatga tctctgtaga tattctgttt tattttggtc     1680

atctttagaa gttatcagga atgtgtttaa aacaagaaga gaacttttct aaggaatgat     1740

acatagaaaa gattttattt taaaatgagt tgtaaagctt gtgtttcttt gttgctgcaa     1800

gctatctgcc caagttaatg caaatggaca cattttttat gtcagaaaaa cacacacaca     1860

cacacacaca cacacacaca cacacgaaaa acaaagaaaa aaatgcttga gctttttcta     1920

acttcccctt gcagtctgtt gtgtgagcag cctgtttatt tctctaatat tatgtcagtt     1980

tattctcttt aatggactgt aaaaaaatgt aatcacaaga gtgccaaata tcttgaaatg     2040

ccaaaaggca ttttagtttc ttttctctgt gctctgagtc cacgtacagg aatgcttgga     2100

gtgtcttttc tgttatttat agggattctc ttaaggcaca ccagctgcct gttttgcatg     2160

gtatttgcaa aaatgcctct tgcgtgagga aatcttttac cattttttgt ttgcaacttt     2220

ggacctcaag aggtttccct tcccttcccc gttccctctt ttcttaattc aatattctgt     2280

atgttgcacc ttgaaccagc acacagggct atttctccaa tgtacaataa aagaattgtt     2340

cctgtgtctc aaaaaaaaaa aaaaaaaaaa a                                    2371


<210>  1744
<211>  4504
<212>  DNA
<213>  homo sapiens

<400>  1744
agtcagaccc aggaggagtg aggtcaattg ccctttagtc ccaggactaa ccggaagctt       60

ctgcaacagg aggacattga aaataagatg gaacccatcc acataaggat ttgcctcaaa      120

gggcactgca aaaattgaac agaggaatcc caaggaagct gcctgaattt gcctgtatac      180

tctcgttctg cgacttataa aggaccagac aaatcaaatt agtggttttg gtttccgcca      240

gctgtggatg cctttgacat tatgaccgca gaggattcca ccgcagccat gagcagtgac      300

tcggccgccg ggtcctccgc caaggtgccc gagggcgtgg cgggcgcgcc caacgaggca      360

gcactgctgg cgctgatgga gcgcacgggc tacagcatgg tgcaagagaa cgggcagcgc      420

aagtacggcg gcccaccgcc cggctgggag ggcccgcacc cgcagcgtgg ctgcgaggtc      480

ttcgtgggca agatcccgcg cgacgtgtac gaggacgagc tggtgcccgt gttcgaggcc      540

gtgggccgca tctacgagct gcgcctcatg atggactttg acggcaagaa ccgcggctac      600

gccttcgtca tgtactgcca caagcacgag gccaagcgcg cagtgcgtga gctcaacaac      660

tacgagatcc gcccgggccg cctgctcggc gtgtgctgca gcgtggacaa ctgccgcctc      720

ttcatcggcg ggatccccaa gatgaagaag cgcgaggaaa tcctggagga gattgccaag      780

gtcaccgagg gcgtgctgga cgtgatcgtc tacgccagcg cggccgacaa gatgaagaac      840

cgcggcttcg ccttcgtgga gtacgagagc caccgcgcgg ctgccatggc tcgccgcaag      900

ctcatgcctg gccgcatcca gctgtggggc caccagatcg ccgtggactg ggccgaacct      960

gagatcgacg tggacgagga cgtgatggag accgtgaaga tcctctacgt gcgcaacctc     1020

atgatcgaga ccaccgagga caccatcaag aagagcttcg gccagttcaa ccccggctgc     1080

gtggagcgcg tcaagaagat ccgcgactac gccttcgtgc acttcaccag ccgcgaggat     1140

gccgtgcatg ccatgaacaa cctcaacggc actgagctgg agggctcgtg cctggaggtc     1200

acgctggcca agcccgtgga caaggagcag tactcgcgct accagaaggc agccaggggc     1260

ggcggcgcgg ctgaggcagc gcagcagccc agctacgtgt actcctgcga cccctacaca     1320

ctggcctact acggctaccc ctacaacgcg ctcattgggc ccaacaggga ctactttgtg     1380

aaagtagcca tccctgccat tggggctcag tattccatgt ttccagcagc tccagcccct     1440

aaaatgattg aagatggcaa aatccacaca gtggagcaca tgatcagccc cattgctgtg     1500

cagccagacc cagccagtgc tgctgccgcc gcagccgcgg ccgcagccgc cgcagccgct     1560

gtcattccca ctgtgtcgac gccaccacct ttccagggcc gcccaataac tccagtatac     1620

acggtggctc caaacgttca gagaattcct actgccggga tctacggggc cagttacgtg     1680

ccatttgctg ctccagctac agccacgatc gccacactac agaagaacgc ggcagccgcg     1740

gccgccatgt atggaggata cgcaggctac atacctcagg ccttccctgc tgctgccatt     1800

caggtcccca tccccgacgt ctaccagaca tactgaggct ggtgaccagc acgaagacag     1860

accacacaaa caccactgaa ggaacgcttg actatttatg aagaaggaac atgttggatt     1920

cacacatgca acctgaaagt gaagaatgtt agcagattta tttctgaatt attttatata     1980

catgaagttt tcactagttt tttaagacta ttttcaactt agcatgccta cgttcataca     2040

tttccaaaag acttgcaatg gttcgtgcct tcattccatc ttttaaaaat ttgtatgctg     2100

tactacattt gtatagaggt ttttgttgtt gtttttttaa ggatatattt tcagtatgaa     2160

ggttattttc ttaacttctg cactccagag atttctattt tgtagtacct tcaataatat     2220

atcaactata tattaaaaaa gcacacttga ggagctaggg aactattttg aaaaatatat     2280

acaatattta aagatacaaa cagtagtgct taaaaatact acataaagca ttattttaaa     2340

ggttatactg gaaagtgcaa ttttaaaatg agtaaaacct ctgtatttct gctggcatta     2400

agggttgatg gtgttaccat gtatcatcat ggcggtacta ttttttaaaa gaaattaaac     2460

actggatctc tccttaagcc aacattgaaa agacttgccg cacttctgag tccaaacact     2520

ggaaagctct cctttgccac cgttagccgg ggctcattct ccatgtgcct tagccttaaa     2580

catgccccca ctcccacatc tctcaccctg tcccctcctc cccagattcc caatcccacc     2640

gcaatgtttg gcaagcctag gactgataag tagctctgat agaggagctg gtggctttta     2700

tacttcttcc tgggtttttg ttggggtttg ttgtttcgtt gttttttgtt tttttttttg     2760

tttggttggg gaagtattgt cttctacgtg tgctattttc agtagcagag taagcacaag     2820

gttttaatcg agttgcataa gacacctttg catagctatt taattgccca atgtaaaact     2880

ttaatgccat ttctaatgct tttattcatt tttgaagtat gagtttgtag ggacaaagaa     2940

tgtatgttat cgtagacaag acccccagag actcttttca gcagaaagtt atgcttctag     3000

ttgccttacc atgtttcttg caaaactgtc catggtcctc aagggtgttg gaaacattat     3060

gtttattaaa tgggcctctc ttcctttgct gtgcacttga tgggtgaact ggattggggt     3120

gtgcacatcc aggaggagga ggagagacct gtagaagttt aaagatagtt tgtaaatatc     3180

ttctaatgct tgtttttagt ccttttatgt tggagaagtt catggtatgt agtttaatgc     3240

aaaatgaaac cattttattt caatgttatt aaaaaggttt gttttattag gaagttaatg     3300

tattgttgca gtgttttgtg cctgtttaaa ggcttttgtt tagcagagtg aatgtaaaat     3360

acagtaaaat gttaagattg tcatctactt tttaaaaaaa aatatcaact tggaattgtt     3420

ttttaaaggc tcaatcaagg aagtgaggtg tgcaataagg tagcaagtaa aacgcagttg     3480

cgtttttatg tcatgttaga gatccataca attttccact cacgggattt ttgttgatgg     3540

ctgaattctt gtggattcat aagaggatca tgcccttagc aagtactttt gttttgtttt     3600

aaattaagag attcccaaat gcctttttcc ccctcatctt gaaatgagat gagtttttat     3660

gtgtaagcaa tatttattta actattctat aaaattattg agtgcctact gaggccttta     3720

agcaccgcta acattccttt ccatcattct tttaaatgac ataaaataat tgtgcaatgt     3780

tcctgatgat gtaccccaca agctgcattc aaactcaaat ctgtgggaat gagtgactcg     3840

acaaaatgta attcggatca gatcctcatc ccctgactgt gtgaaaaaag tactctcctt     3900

ctagtgaagg attgtcacag agtttcactg gatgaaacta tgacccagta ttcttactgt     3960

attttacata tgcctgtaaa ttatttgcaa aaaagaagaa gaagaggaag aaagaaaaga     4020

aagaaaagaa agaaagaaag aaagaaagaa agaaagaaag aaagaaagaa agaaagaaag     4080

aaagaaaaag aaagaaagaa taaaaaaaaa tgataacatg gcaaccacca aactccctta     4140

aaaacaaaca ttggtgacat ggccaattaa gtatcagtga gcctcctatc tgggacttat     4200

ctgttcctat tgtttcaaaa ccatttcatg tacactactg aggtaagttt ataacttgaa     4260

atgtgaactt tttttttttt tagtgttaag aacaaactat ataaatgtaa aaaaaaagtt     4320

ttagagttct gttttcaaac attgctagtg gtttagttaa ctttagctgc tttatatttg     4380

aaaagctttt atttagatct tgctccattt acagtacatt cttaggatgt atgtagtaaa     4440

taaagctttc tttaaagcaa tcgcaagacc ttattttaaa ttgtgaaaaa aaaaaaaaaa     4500

aaaa                                                                  4504


<210>  1745
<211>  1563
<212>  DNA
<213>  homo sapiens

<400>  1745
cgcagagttt caaatcggct gcggtgggcg aggagcagct gtgctgcggc tgtgctcggc       60

cttagtggtg tcggggtcta gtggacagag aagactcttg gccaggcaga tggcttctcg      120

gtggcagaac atggggacct ccgtgcgccg gagatctctc cagcaccagg agcagctgga      180

ggacagcaag gagctgcagc ctgtggtcag ccatcaggag acctctgtag gggccctggg      240

gtccctgtgc agacagttcc aaaggaggct gcccctgaga gccgtcaacc tcaacctccg      300

cgcagggccc tcctggaaac gcctggaaac cccagagcca ggtcagcagg gcctccaggc      360

tgcagctcgc tcagctaaga gtgctttggg tgccgtgtcc cagagaatcc aggagtcctg      420

ccaaagtggc accaagtggc tggtggagac ccaggtgaag gccaggaggc ggaagagagg      480

agcacagaag ggcagtggat ccccaactca cagcctgagc cagaagagca cccggctgtc      540

tggagccgcc cctgcccact cagccgcaga cccctgggag aaggagcatc accgcctctc      600

tgtccggatg ggctcacatg cccacccatt acggcgatca aggcgggagg ctgccttccg      660

gagcccctac tcctcaacag agcccctctg ctctcccagc gagtctgaca gtgacctaga      720

gcctgtgggg gcgggaattc agcatctcca gaagctgtcc caagagctag atgaagccat      780

tatggcggaa gagagtggtg acatcgtctc tctcattcat gactgaggaa gtgcctgcag      840

gaaacaagcc ctgtctgacc gccaaggctt catactcaag gatgtctatg cttccccgtg      900

agcttcctgg aaaaaacccc cgggagtcgt cagtacccct gggccactgc taacaagcac      960

ctaacaaggg gcccagagcc ccctgctcca gccacatctg gacccatcag tgactgcctg     1020

ccatagcctg agagtgtctt ggggagacct tgcagagggg gagaattgtt ccttctgctt     1080

tcctagggga ctcttgagct tagaaactca tcgtacactt gaccttgagc cttctatttg     1140

cctcatctat aacatgaagt gctagcatca gatatttgag agctcttagc tctgtacccg     1200

ggtgcctggt ttttggggag tcatccgcag agtcactcac ccactgtgtt tctggtgcca     1260

aggctcttga gggccccact ctcatccctc ctttccctac cagggactcg gaggaaggca     1320

taggagatat ttccaggctt acgaccctgg gctcacgggt acctatttat atgctcagtg     1380

cagagcactg tggatgtgcc aggaggggta gccctgttca agagcaattt ctgccctttg     1440

taaattattt aagaaacctg ctttgtcatt ttattagaaa gaaaccagcg tgtgactttc     1500

ctagataaca ctgctttctc ataataaaga ctatttgcat ttgaaaaaaa aaaaaaaaaa     1560

aaa                                                                   1563


<210>  1746
<211>  2462
<212>  DNA
<213>  homo sapiens

<400>  1746
acctgtacct cgcaagaatg catacaaact ccagggctgc tctctcctgg agagggaggg       60

aggggattta aaaacctgca gcaacatggg ggaggaggct gtttgtcctt ctctctctgg      120

ggaagtaact cgctcaaact gccttccttg ctgagctgct tcgcgtagct ttgaggaagg      180

tctagtgaaa ttggtctttc cattacatct ggatgtacta ccagagagtt ctgctgctgt      240

tgtttttttt agcttttctt tctttgagtc tttaaagggc aattgtcgac actctgcaaa      300

cataccgatt tgttgtctgc ccactttgga gtcttcaatc tgggcagtaa ctatttaccc      360

tttttcctgc tagcctgtcc ccctctctgg attgaagtca cctgctaaga caatggacta      420

ccgaccagac tcccggaaat catgttggta ggatcccagt ctttttcgcc tggagggccc      480

aatgggatca ttagaagcca gtcctttgcg ggtttcagcg gcctccagga aaggcgatcc      540

aggtgtaact ccttcattga aaattcctcc gctctcaaga agcctcaggc caaactgaag      600

aaaatgcaca atttaggcca caaaaacaac aatcccccca aagagcctca gcctaaaagg      660

gtggaagaag tctacagggc cttgaaaaat ggacttgatg aatatctgga ggttcaccag      720

acggagctgg acaagttgac agctcagtta aaagatatga aaagaaactc tcgcctgggt      780

gtactgtatg acctagacaa gcaaattaaa acaattgaaa gatacatgag acgcctggag      840

tttcatataa gtaaggtaga tgaactctat gaagcttatt gtatccagcg acgcctccag      900

gatggtgcca gcaaaatgaa gcaagccttc gcaacatccc ctgccagcaa agctgcccgg      960

gagagtctga cagagatcaa tcggagcttc aaggagtaca cagagaatat gtgcaccatt     1020

gaagtggagc tagagaatct gctgggagaa ttctccatca agatgaaagg tctggctggc     1080

tttgcacgcc tctgtcctgg agatcaatat gaaattttca tgaagtatgg ccggcagcgg     1140

tggaaactga aaggcaaaat agaagtaaat ggcaagcaga gctgggatgg agaagaaaca     1200

gtttttctgc ccctgatagt tgggttcatc tccatcaagg tcacggagct caaagggcta     1260

gcaactcaca tcctggtagg tagcgtgacc tgtgagacca aagagctgtt tgcagcccga     1320

cctcaggtag tggctgtcga catcaatgac cttggtacca tcaaactgaa cctggaaatc     1380

acctggtatc catttgacgt ggaggacatg accgcatcct caggcgctgg gaacaaggca     1440

gcagcccttc agaggagaat gtccatgtac agccagggta ccccggaaac gcccaccttc     1500

aaagaccact ccttcttttc aaatctacct gatgacatct ttgaaaatgg aaaggcagcc     1560

gaggagaaaa tgccactgtc gctcagcttc agtgacctgc ccaacgggga ctgcgccctc     1620

acctcccact caacaggctc cccttccaac tcaacaaatc cagaaattac catcacccct     1680

gcggagttta acctcagcag cttggcctcc cagaatgagg gtatggatga caccagctca     1740

gcatcttcca ggaactccct gggagaaggc caagagccaa agtcacacct gaaggaggaa     1800

gacccagagg agcccagaaa acctgcctcg gccccatctg aggcttgccg ccgacagtcc     1860

tcaggtgctg gggctgagca cctgttcctt gagaatgatg ttgcagaagc acttctgcaa     1920

gagtctgagg aggcctctga gctcaagcct gtggaactgg acacttcgga aggaaacatc     1980

acaaagcagc tggtcaagag gctcacatct gcagaggtgc caatggccac agacaggctg     2040

ctctctgagg gttctgttgg tggagaatct gaaggctgca gatcctttct agatggaagc     2100

ttagaggatg cttttaatgg gcttttactt gcattagaac cacataaaga gcagtataaa     2160

gagtttcagg atctgaacca agaagtcatg aatttggatg atattctaaa aaagtagaga     2220

agatcctcta atggatccca gtgtgcccat ccctcaacct cctcagtgat caactcatgg     2280

ccaatcttgt ttcctattct tcaacctgct gacttccctc tggattcttc tgcaaccagt     2340

cccagatatt gtgccatttt atccatggtt gtacttcttt tttggatata aagattttta     2400

aatgcatttt ttaaatgcta acaaaaaata aaaacttgaa acaaaaaaaa aaaaaaaaaa     2460

aa                                                                    2462


<210>  1747
<211>  5696
<212>  DNA
<213>  homo sapiens

<400>  1747
acaagtgacg ccgccggccc ccgcgccgcg cctccccctc ctcacggctc ccgcccctcc       60

gcccgctccg ccgctctagc tccgcgctcc gccaccctcg cgcccgccag ccccgcaact      120

tcaccccgcg cgccgcagct gctgcgagcg gacgcggcag ggcagccggc gctggggaca      180

gctcgcgtcc acccgacttc ctcccggggt ccccttcacc caagtgagcc agctcaggct      240

gtctgcaaag ccggaggtgc gggcagctcc gggcattgca ttggtgcgga ggcttttata      300

tgccagagaa ccctgagtgt gcccctgaca tgacaaggag ccgtcgtcgt taggactacc      360

gaccagactc ccggaaatca tgttggtagg atcccagtct ttttcgcctg gagggcccaa      420

tgggatcatt agaagccagt cctttgcggg tttcagcggc ctccaggaaa ggcgatccag      480

gtgtaactcc ttcattgaaa attcctccgc tctcaagaag cctcaggcca aactgaagaa      540

aatgcacaat ttaggccaca aaaacaacaa tccccccaaa gagcctcagc ctaaaagggt      600

ggaagaagtc tacagggcct tgaaaaatgg acttgatgaa tatctggagg ttcaccagac      660

ggagctggac aagttgacag ctcagttaaa agatatgaaa agaaactctc gcctgggtgt      720

actgtatgac ctagacaagc aaattaaaac aattgaaaga tacatgagac gcctggagtt      780

tcatataagt aaggtagatg aactctatga agcttattgt atccagcgac gcctccagga      840

tggtgccagc aaaatgaagc aagccttcgc aacatcccct gccagcaaag ctgcccggga      900

gagtctgaca gagatcaatc ggagcttcaa ggagtacaca gagaatatgt gcaccattga      960

agtggagcta gagaatctgc tgggagaatt ctccatcaag atgaaaggtc tggctggctt     1020

tgcacgcctc tgtcctggag atcaatatga aattttcatg aagtatggcc ggcagcggtg     1080

gaaactgaaa ggcaaaatag aagtaaatgg caagcagagc tgggatggag aagaaacagt     1140

ttttctgccc ctgatagttg ggttcatctc catcaaggtc acggagctca aagggctagc     1200

aactcacatc ctggtaggta gcgtgacctg tgagaccaaa gagctgtttg cagcccgacc     1260

tcaggtagtg gctgtcgaca tcaatgacct tggtaccatc aaactgaacc tggaaatcac     1320

ctggtatcca tttgacgtgg aggacatgac cgcatcctca ggcgctggga acaaggcagc     1380

agcccttcag aggagaatgt ccatgtacag ccagggtacc ccggaaacgc ccaccttcaa     1440

agaccactcc ttctttaggt ggctgcatcc ttccccagac aagcccaggc ggctgtctgt     1500

cttgagtgcc ttgcaagaca ctttctttgc caagctgcac cgcagccgct ccttcagtga     1560

cctgccctcc ctcaggccga gtcccaaggc cgtgctagag ctctattcaa atctacctga     1620

tgacatcttt gaaaatggaa aggcagccga ggagaaaatg ccactgtcgc tcagcttcag     1680

tgacctgccc aacggggact gcgccctcac ctcccactca acaggctccc cttccaactc     1740

aacaaatcca gaaattacca tcacccctgc ggagtttaac ctcagcagct tggcctccca     1800

gaatgagggt atggatgaca ccagctcagc atcttccagg aactccctgg gagaaggcca     1860

agagccaaag tcacacctga aggaggaaga cccagaggag cccagaaaac ctgcctcggc     1920

cccatctgag gcttgccgcc gacagtcctc aggtgctggg gctgagcacc tgttccttga     1980

gaatgatgtt gcagaagcac ttctgcaaga gtctgaggag gcctctgagc tcaagcctgt     2040

ggaactggac acttcggaag gaaacatcac aaagcagctg gtcaagaggc tcacatctgc     2100

agaggtgcca atggccacag acaggctgct ctctgagggt tctgttggtg gagaatctga     2160

aggctgcaga tcctttctag atggaagctt agaggatgct tttaatgggc ttttacttgc     2220

attagaacca cataaagagc agtataaaga gtttcaggat ctgaaccaag aagtcatgaa     2280

tttggatgat attctaaaat gcaagccagc agtaagccgc agcaggtctt ccagtttaag     2340

tctcacagtt gaaagtgctt tagaaagctt tgatttcctg aacacctctg attttgacga     2400

ggaggaggat ggtgatgagg tttgtaatgt tggcggaggt gctgactcag tattttcaga     2460

cactgagact gagaaacaca gttacaggtc ggttcaccca gaagccaggg ggcatctcag     2520

tgaagcgctc actgaagaca caggagttgg gaccagtgtg gcaggaagtc ctctcccact     2580

gaccacaggc aacgagagcc tggacatcac catcgtcagg cacctccagt actgcaccca     2640

actcgtgcag caaattgttt tctcaagcaa aaccccattt gtggcaagaa gtctcttaga     2700

gaagctttct aggcagatcc aagtgatgga gaaactcgca gctgtcagtg atgagaacat     2760

aggaaatatc agttctgttg tggaagccat accagaattt cacaaaaagc tgtctttgct     2820

gtcattctgg accaagtgct gcagccctgt tggtgtctac cacagcccag cggacagagt     2880

gatgaagcag ctggaggcca gctttgccag aactgtcaac aaagaatatc caggacttgc     2940

agacccagtg tttcgaaccc tggtgtccca aattctggac cgggctgagc ctctgctttc     3000

ctccagcctg tcctcggaag tcgtcactgt tttccagtat tacagttact tcaccagcca     3060

cggcgtcagt gacctggaga gttacctgag ccagctggcc aggcaagttt ccatggttca     3120

gactctgcaa tcactaagag atgaaaaact gctacaaacc atgagtgacc ttgctcccag     3180

caacctcctg gcccagcagg aagtactcag gactctggct ctgctattaa ccagagagga     3240

caacgaagtt agcgaggctg tgacgcttta cttggcagca gcctccaaaa atcagcattt     3300

cagggaaaag gccttgctct attactgtga agcactaaca aagacaaacc tccagctcca     3360

gaaagcagct tgcctggctc tgaaaatcct tgaggctact gaaagcatta aaatgctggt     3420

gacattgtgt caatctgata ctgaagaaat cagaaatgtg gcctcagaaa ccctcttgtc     3480

tctgggagaa gatgggcggc tggcatatga acaattggac aaatttcctc gagactgtgt     3540

taaagtcgga ggtcgtcatg gaactgaagt tgccacagcc ttttaattac aggttaactg     3600

cctaacagct gtcttaatat ctggcccttt tcatcaggat ggtgctgtgg tttgggctgg     3660

aaattgttta gagcctgaga gacacgacaa ctgaaataaa aatgtaggcc aggtgcagtg     3720

gctcatgcct gtaatcccag tactttggga ggccaacgca ggagaattgc ttaagcccag     3780

gaggttcaag accaacctgg gcaacatagc aaggccctgt ctctacaaaa aaaatagttt     3840

aattagtcag gcgtggtggc atgcacctgt agtcccagct acttgggagg ctaaggtggg     3900

aggattgctt gagcccagaa gattcaggct gcagtgagcc ataattgccc cactgcactc     3960

cagactgggt gacagagcaa aaccctgtct caaaaaacaa aacaacaaca acaactaaaa     4020

aaacatgtta tagaaagaat tcagagtctc gtttcacagt acctatctac ttttcctttg     4080

gccaatatag aatagggcta tggtataatt caaatatatt acatcgtcga ttgtgtctaa     4140

taatactcag tgaaagagtc catcttatct taatatgtat gaaatttaaa aatagccatc     4200

tttgtacttt tttgcaagtt tctctataag cttgaaatag tcatgtgata cttcgacaaa     4260

catcatatgc cttgcagttt ttctcggtcg tgttctcagg gttgagtagt ccccttagct     4320

acctaacttt actttcaata caaagcacaa aaaagaatat cttcaaataa aagtttgcct     4380

gcagaacctg gcaaaatgac ccattaggag agtttagatg ttttaatttt atgtgctccc     4440

agctactctg gagtctgagg tgggaggatc acttgaggca gaggttgcag taagctgaga     4500

ttacactact gcactccagc ccatgtgaca gaggaatgag agccagtctc aaaaaaaaaa     4560

acaaaaaact cccataattt attttgtttc ttttccccat cctgaaaatt cccaaatcat     4620

gtttccatta tggaaaaatg ataagtaaat gactaagaac tacattaaga ttatgcctat     4680

acacttaaac aaaaaactca aagcttatgc tttttttttt ttaattaatg agagctattt     4740

tttatgatat tcttaccata ggggtgtttt gctgctaaga caaatcaaaa ccaaaagctg     4800

tagattcaca aacctgtgat gctctttgag gtggaggaac ctagaagtca gagaaatcct     4860

aatggagtag gagtggagga acatttaaag tggtccctcc ttctgtaaaa atgaccgtgg     4920

gattagaaag aaggacatcc tgaggggtgg ttactgcccc cagggaaatc actcactggt     4980

aggattccct ggccaaatag ttcaaacatc aggtcccatt attgcttcag tatcagagat     5040

gcaagttcat taagcaaagt acaagaccat tcagtagctc ttattaaaat atcttttctt     5100

cctctaaaga gtgtacaagg tggggtatgc caaggtatca aaacaatata tgtgagtgta     5160

atttaaactg tggaatatca actgtactat ggacgtgttt gtatcattta gatgtcattt     5220

taaatattta cattttagca agacttttaa aaaggactca tttcatttca aagtgcaaat     5280

tgtttgccag gcttctggca aatggttctt tcaactgtga acttatcgtg tacatatctg     5340

tatatttata aatattatat atattcatac atccttcact ttaaaggtac attgtacagt     5400

ctgtagttag gaggtatagc ctatagctta tgttaaatgg ttgaaatggt tctttttata     5460

gaaagtcaaa cacagatgtt acaggatttt gtgtttggtt tgtcattttt ttatttttta     5520

ttttgactat tgcatgagta attaattcca gatcttttgt attcacttct gtattttatg     5580

tttggttgag gggtgctttt agttgtgtgg catttgtatt cattgatctt tcagtcatgt     5640

aagttaaaat aaaaattatt tttgaattac tagcatcaaa aaaaaaaaaa aaaaaa         5696


<210>  1748
<211>  2462
<212>  DNA
<213>  homo sapiens

<400>  1748
acctgtacct cgcaagaatg catacaaact ccagggctgc tctctcctgg agagggaggg       60

aggggattta aaaacctgca gcaacatggg ggaggaggct gtttgtcctt ctctctctgg      120

ggaagtaact cgctcaaact gccttccttg ctgagctgct tcgcgtagct ttgaggaagg      180

tctagtgaaa ttggtctttc cattacatct ggatgtacta ccagagagtt ctgctgctgt      240

tgtttttttt agcttttctt tctttgagtc tttaaagggc aattgtcgac actctgcaaa      300

cataccgatt tgttgtctgc ccactttgga gtcttcaatc tgggcagtaa ctatttaccc      360

tttttcctgc tagcctgtcc ccctctctgg attgaagtca cctgctaaga caatggacta      420

ccgaccagac tcccggaaat catgttggta ggatcccagt ctttttcgcc tggagggccc      480

aatgggatca ttagaagcca gtcctttgcg ggtttcagcg gcctccagga aaggcgatcc      540

aggtgtaact ccttcattga aaattcctcc gctctcaaga agcctcaggc caaactgaag      600

aaaatgcaca atttaggcca caaaaacaac aatcccccca aagagcctca gcctaaaagg      660

gtggaagaag tctacagggc cttgaaaaat ggacttgatg aatatctgga ggttcaccag      720

acggagctgg acaagttgac agctcagtta aaagatatga aaagaaactc tcgcctgggt      780

gtactgtatg acctagacaa gcaaattaaa acaattgaaa gatacatgag acgcctggag      840

tttcatataa gtaaggtaga tgaactctat gaagcttatt gtatccagcg acgcctccag      900

gatggtgcca gcaaaatgaa gcaagccttc gcaacatccc ctgccagcaa agctgcccgg      960

gagagtctga cagagatcaa tcggagcttc aaggagtaca cagagaatat gtgcaccatt     1020

gaagtggagc tagagaatct gctgggagaa ttctccatca agatgaaagg tctggctggc     1080

tttgcacgcc tctgtcctgg agatcaatat gaaattttca tgaagtatgg ccggcagcgg     1140

tggaaactga aaggcaaaat agaagtaaat ggcaagcaga gctgggatgg agaagaaaca     1200

gtttttctgc ccctgatagt tgggttcatc tccatcaagg tcacggagct caaagggcta     1260

gcaactcaca tcctggtagg tagcgtgacc tgtgagacca aagagctgtt tgcagcccga     1320

cctcaggtag tggctgtcga catcaatgac cttggtacca tcaaactgaa cctggaaatc     1380

acctggtatc catttgacgt ggaggacatg accgcatcct caggcgctgg gaacaaggca     1440

gcagcccttc agaggagaat gtccatgtac agccagggta ccccggaaac gcccaccttc     1500

aaagaccact ccttcttttc aaatctacct gatgacatct ttgaaaatgg aaaggcagcc     1560

gaggagaaaa tgccactgtc gctcagcttc agtgacctgc ccaacgggga ctgcgccctc     1620

acctcccact caacaggctc cccttccaac tcaacaaatc cagaaattac catcacccct     1680

gcggagttta acctcagcag cttggcctcc cagaatgagg gtatggatga caccagctca     1740

gcatcttcca ggaactccct gggagaaggc caagagccaa agtcacacct gaaggaggaa     1800

gacccagagg agcccagaaa acctgcctcg gccccatctg aggcttgccg ccgacagtcc     1860

tcaggtgctg gggctgagca cctgttcctt gagaatgatg ttgcagaagc acttctgcaa     1920

gagtctgagg aggcctctga gctcaagcct gtggaactgg acacttcgga aggaaacatc     1980

acaaagcagc tggtcaagag gctcacatct gcagaggtgc caatggccac agacaggctg     2040

ctctctgagg gttctgttgg tggagaatct gaaggctgca gatcctttct agatggaagc     2100

ttagaggatg cttttaatgg gcttttactt gcattagaac cacataaaga gcagtataaa     2160

gagtttcagg atctgaacca agaagtcatg aatttggatg atattctaaa aaagtagaga     2220

agatcctcta atggatccca gtgtgcccat ccctcaacct cctcagtgat caactcatgg     2280

ccaatcttgt ttcctattct tcaacctgct gacttccctc tggattcttc tgcaaccagt     2340

cccagatatt gtgccatttt atccatggtt gtacttcttt tttggatata aagattttta     2400

aatgcatttt ttaaatgcta acaaaaaata aaaacttgaa acaaaaaaaa aaaaaaaaaa     2460

aa                                                                    2462


<210>  1749
<211>  3273
<212>  DNA
<213>  homo sapiens

<400>  1749
attgaggtta gggcggcccc atccgtcggt ctccgccagc taggatctcc cccgccgtcc       60

gcccccgccc ctcgtctgcc tcccccgccc gcgcctccgc ccgcgcttcc ctttcctgcc      120

tcgcgcccca ctccctttcc tcccctccct gtttcccttc ctgtccttcc cagctcacgc      180

tctctttccc tgccgcctgc ctttcttttt tccttttttt gcattggcgt cttggggctg      240

ttacacacac gcgcgctgtc cattgcagct tacataaagg cgggcgcgat tatgcaatta      300

tattgttagc gatatttcaa gagcaatggc tcgttttctt aggatttcaa cacgaaggca      360

tcatgcattt ttgaaaaact agtattgaga ataatacctt gcaacgtaaa gaatgttttt      420

tggtattttt acacaatctc tactttgacc aaacgagtct ggacagtttt cttttaatgg      480

aaaataggag aaatggagga aagaatggaa atgatttctg aaaggccaaa agagagtatg      540

tattcctgga acaaaactgc agagaaaagt gattttgaag ctgtagaagc acttatgtca      600

atgagctgca gttggaagtc tgattttaag aaatacgttg aaaacagacc tgttacacca      660

gtatctgatt tgtcagagga agagaatctg cttccgggaa cacctgattt tcatacaatc      720

ccagcatttt gtttgactcc accttacagt ccttctgact ttgaaccctc tcaagtgtca      780

aatctgatgg caccagcgcc atctactgta cacttcaagt cactctcaga tactgccaaa      840

cctcacattg ccgcaccttt caaagaggaa gaaaagagcc cagtatctgc ccccaaactc      900

cccaaagctc aggcaacaag tgtgattcgt catacagctg atgcccagct atgtaaccac      960

cagacctgcc caatgaaagc agccagcatc ctcaactatc agaacaattc ttttagaaga     1020

agaacccacc taaatgttga ggctgcaaga aagaacatac catgtgccgc tgtgtcacca     1080

aacagatcca aatgtgagag aaacacagtg gcagatgttg atgagaaagc aagtgctgca     1140

ctttatgact tttctgtgcc ttcctcagag acggtcatct gcaggtctca gccagcccct     1200

gtgtccccac aacagaagtc agtgttggtc tctccacctg cagtatctgc agggggagtg     1260

ccacctatgc cggtcatctg ccagatggtt ccccttcctg ccaacaaccc tgttgtgaca     1320

acagtcgttc ccagcactcc tcccagccag ccaccagccg tttgcccccc tgttgtgttc     1380

atgggcacac aagtccccaa aggcgctgtc atgtttgtgg taccccagcc cgttgtgcag     1440

agttcaaagc ctccggtggt gagcccgaat ggcaccagac tctctcccat tgcccctgct     1500

cctgggtttt ccccttcagc agcaaaagtc actcctcaga ttgattcatc aaggataagg     1560

agtcacatct gtagccaccc aggatgtggc aagacatact ttaaaagttc ccatctgaag     1620

gcccacacga ggacgcacac aggagaaaag cctttcagct gtagctggaa aggttgtgaa     1680

aggaggtttg cccgttctga tgaactgtcc agacacaggc gaacccacac gggtgagaag     1740

aaatttgcgt gccccatgtg tgaccggcgg ttcatgagga gtgaccattt gaccaagcat     1800

gcccggcgcc atctatcagc caagaagcta ccaaactggc agatggaagt gagcaagcta     1860

aatgacattg ctctacctcc aacccctgct cccacacagt gacagaccgg aaagtgaaga     1920

gtcagaacta actttggtct cagcgggagc cagtggtgat gtaaaaatgc ttccactgca     1980

agtctgtggc cccacaacgt gggcttaaag cagaagcccc acagcctggc acgaaggccc     2040

cgcctgggtt aggtgactaa aagggcttcg gccacaggca ggtcacagaa aggcaggttt     2100

catttcttat cacataagag agatgagaaa gcttttattc ctttgaatat tttttgaagg     2160

tttcagatga ggtcaacaca ggtagcacag attttgaatc tgtgtgcata tttgttactt     2220

tacttttgct gtttatactt gagaccaact tttcaatgtg attcttctaa agcactggtt     2280

tcaagaatat ggaggctgga aggaaataaa cattacggta cagacatgga gatgtaaaat     2340

gagtttgtat tattacaaat attgtcatct ttttctagag ttatcttctt tattattcct     2400

agtctttcca gtcaacatcg tggatgtagt gattaaatat atctagaact atcattttta     2460

cactattgtg aatatttgga attgaacgac tgtatattgc taagagggcc caaagaattg     2520

gaatcctcct taatttaatt gctttgaagc atagctacaa tttgtttttg catttttgtt     2580

ttgaaagttt aacaaatgac tgtatctagg catttcatta tgctttgaac tttagtttgc     2640

ctgcagtttc ttgtgtagat ttgaaaattg tataccaatg tgttttctgt agactctaag     2700

atacactgca ctttgtttag aaaaaaaact gaagatgaaa tatatattgt aaagaaggga     2760

tattaagaat cttagataac ttcttgaaaa agatggctta tgtcatcagt aaagtacctt     2820

tatgttatga ggatataatg tgtgctttat tgaattagaa aattagtgac cattattcac     2880

aggtggacaa atgttgatgt tgtcctgtta atttataggc gttttttggg gatgtggagg     2940

tagttgggta gaaaaattat tagaacattc acttttgtta acagtatttc tcttttattc     3000

tgttatatag tggatgatat acacagtggc aaaacaaaag tacattgctt aaaatatata     3060

gtgaaaaatg tcactatatc ttcccattta acattgtttt tgtatattgg gtgtagattt     3120

ctgacatcaa aacttggacc cttggaaaac aaaagtttta attaaaaaaa atccttgtga     3180

cttacaattt gcacaatatt tcttttgttg tactttatat cttgtttaca ataaagaatt     3240

ccctttggta tatggaaaaa aaaaaaaaaa aaa                                  3273


<210>  1750
<211>  6256
<212>  DNA
<213>  homo sapiens

<400>  1750
gcggccgccg cctccgcccc gcgttcgggg ccttcccgac cctgcactgc tgccgtccgc       60

ccgcccggcc gctcttctct tcgccgtggg agccgctccg ggcgcagggc cgcgcgccga      120

gccccgcagg ctgcagcgcc gcggcccggc ccggcgcccc ggcaacttcg ccgagagttg      180

aggcgaagtt tgggcgaccg cggcaggccc cggccgagct cccctctgcg cccccggcgt      240

cccgtcgagc ccagccccgc cgggggcgct cctcgccgcc cgcgcgccct ccccagccat      300

gtcgtccatc ctgcctttca ctcccccgat cgtgaagcgc ctgctgggct ggaagaaggg      360

cgagcagaac gggcaggagg agaaatggtg cgagaaggcg gtcaagagcc tggtcaagaa      420

actcaagaag acggggcagc tggacgagct ggagaaggcc atcaccacgc agaacgtcaa      480

caccaagtgc atcaccatcc ccaggtccct ggatggccgg ttgcaggtgt cccatcggaa      540

ggggctccct catgtcatct actgccgcct gtggcgatgg ccagacctgc acagccacca      600

cgagctacgg gccatggagc tgtgtgagtt cgccttcaat atgaagaagg acgaggtctg      660

cgtgaatccc taccactacc agagagtaga gacaccagtt ctacctcctg tgttggtgcc      720

acgccacaca gagatcccgg ccgagttccc cccactggac gactacagcc attccatccc      780

cgaaaacact aacttccccg caggcatcga gccccagagc aatattccag agaccccacc      840

ccctggctac ctgagtgaag atggagaaac cagtgaccac cagatgaacc acagcatgga      900

cgcaggttct ccaaacctat ccccgaatcc gatgtcccca gcacataata acttggacct      960

gcagccagtt acctactgcg agccggcctt ctggtgctcc atctcctact acgagctgaa     1020

ccagcgcgtc ggggagacat tccacgcctc gcagccatcc atgactgtgg atggcttcac     1080

cgacccctcc aattcggagc gcttctgcct agggctgctc tccaatgtca acaggaatgc     1140

agcagtggag ctgacacgga gacacatcgg aagaggcgtg cggctctact acatcggagg     1200

ggaggtcttc gcagagtgcc tcagtgacag cgctattttt gtccagtctc ccaactgtaa     1260

ccagcgctat ggctggcacc cggccaccgt ctgcaagatc ccaccaggat gcaacctgaa     1320

gatcttcaac aaccaggagt tcgctgccct cctggcccag tcggtcaacc agggctttga     1380

ggctgtctac cagttgaccc gaatgtgcac catccgcatg agcttcgtca aaggctgggg     1440

agcggagtac aggagacaga ctgtgaccag taccccctgc tggattgagc tgcacctgaa     1500

tgggcctttg cagtggcttg acaaggtcct cacccagatg ggctccccaa gcatccgctg     1560

ttccagtgtg tcttagagac atcaagtatg gtaggggagg gcaggcttgg ggaaaatggc     1620

catgcaggag gtggagaaaa ttggaactct actcaaccca ttgttgtcaa ggaagaagaa     1680

atctttctcc ctcaactgaa ggggtgcacc cacctgtttt ctgaaacaca cgagcaaacc     1740

cagaggtgga tgttatgaac agctgtgtct gccaaacaca tttacccttt ggccccactt     1800

tgaagggcaa gaaatggcgt ctgctctggt ggcttaagtg agcagaacag gtagtattac     1860

accaccggcc ccctcccccc agactctttt tttgagtgac agctttctgg gatgtcacag     1920

tccaaccaga aacacccctc tgtctaggac tgcagtgtgg agttcacctt ggaagggcgt     1980

tctaggtagg aagagcccgc agggccatgc agacctcatg cccagctctc tgacgcttgt     2040

gacagtgcct cttccagtga acattcccag cccagccccg ccccgccccg ccccaccact     2100

ccagcagacc ttgccccttg tgagctggat agacttggga tggggaggga gggagttttg     2160

tctgtctccc tcccctctca gaacatactg attgggaggt gcgtgttcag cagaacctgc     2220

acacaggaca gcgggaaaaa tcgatgagcg ccacctcttt aaaaactcac ttacgtttgt     2280

cctttttcac tttgaaaagt tggaaggatc tgctgaggcc cagtgcatat gcaatgtata     2340

gtgtctatta tcacattaat ctcaaagaga ttcgaatgac ggtaagtgtt ctcatgaagc     2400

aggaggccct tgtcgtggga tggcatttgg tctcaggcag caccacactg ggtgcgtctc     2460

cagtcatctg taagagcttg ctccagattc tgatgcatac ggctatattg gtttatgtag     2520

tcagttgcat tcattaaatc aactttatca tatgctcttt taaatgtttg gtttatatat     2580

tttctttaaa aatcctgggc tggcacattg actgggaaac ctgagtgaga cccagcaact     2640

gcttctctcc cttctctctc ctgaggtgaa gcttttccag gttttgttga agagatacct     2700

gccagcactt ctgcaagctg aaatttacag aagcaaattc accagaaggg aaacatctca     2760

ggccaacata ggcaaatgaa aagggctatt aaaatatttt tacacctttg aaaattgcag     2820

gcttggtaca aagaggtctg tcatcttccc cctgggatat aagatgatct agctcccggt     2880

agaggatcac cggtgacaac tatagcagtt gtattgtgta acaagtactg ctcccagcag     2940

caattaggga gaaaactagt ctaaattatt tcaactggaa aaaagaaaaa agagtcctct     3000

tcttttccca gccttttgca gaacacagta gacagaactg ccaccttcaa ttggtacttt     3060

attctttgct gctgtttttg tataaaatga cctatcccac gtttttgcat gaatttatag     3120

caggaaaaat caagggattt cctatggaag tcctgcttta ttccaggtga agggaaggaa     3180

gtgtatatac ttttggcaag tcatacagct caaatgtgat gagatttctg atgttagagg     3240

gagatggaga ggcttcctga tgcctcatct gcagggtcct gtgcctctga agttctagcc     3300

atgaggtttc caggtaggac agctgctccc caagcctcct gaggacacag gaagagacgg     3360

aaggagcacc ttgacagact tgtgtgagtc ttctcgaagg agggttgact cagaacccag     3420

agacaataca aaacccctca cttcctctga gagggccaaa tgctgtgagt ctgaagtatg     3480

tgcctggtgt gaaatgatct atggcctgtt tcttacacag gaagccccct gaacctcctg     3540

tacatgtgtt catgttccca gccagctctg agacccagga accaaatatt ccattttggc     3600

ttctgctaga gcagtcatgg ttcctctcct aaaagccatg ggcagcagtt tccgagggcc     3660

tgcatgatcc acctgctgca cgatcctatg agggcttcct gtggcacaca gccctctggg     3720

tgcttgggaa ctagcttcag gcacagcctg attctggtga tccagtgatc tatggaagtc     3780

gtgtcttact ccaggtgaag ggggaaaaaa aaagcctata ctttggcagg ttatgaactt     3840

tgaatgtgat gaaatgacac gtttggctgc atttggatgg tgtcttagaa ccctcattgc     3900

tcagacctga aggctacttc taggagcatg aagtttgagt tttgtgtttt tccaaaggat     3960

acttccttgg ccctttttct ttattgacta gaccaccaga ggaggatgtg tgggattgta     4020

ggcaaaccca cctgtggcat cactgaaaat aaatttgatc atacctaaga ggttaggaaa     4080

tggtgccatt cccaccttag agtgctacat aggtgctttg ggcgtatgta acattagtgt     4140

ccttccttga agccacaagc tagttttctt agttttaaaa tcctgttgta tgaatggcat     4200

ttgtatatta aaacactttt ttaaaggaca gttgaaaagg gcaagaggaa accagggcag     4260

ttctagagga gtgctggtga ctggatagca gttttaagtg gcgttcacct agtcaacacg     4320

accgcgtgtg ttgcccctgc cctgggctcc ccgccatgac atcttcacct tgcagcttgt     4380

gctgagactg acccaagtgc agctagcact gggacacaga tccttgtctt cagcaccttc     4440

caaggagcca acttttattc cctttcctct ctcccctccc cacctcgctt cttcccaatt     4500

tagtaactta gatgcttcca gcacatacgt aggtagctac cccagccggt ttggattaca     4560

ggcctgtgct ggaacatcat ctcagttggc caccttcctg gcaggctgta gacctgacat     4620

tttgagacaa gcctagagtc aggagcaggg actttgactc ttaggaagag cacacatgag     4680

ggcaaggctg ctggcagacg tctccattgt ccttatgttg tctgtgttgt attttttttt     4740

ttttattgac catggtgatt atttttttaa accatcgtta atatactgaa gtgagctata     4800

gcacatatca tgtgcttagt ttgtttattt ttctccatct ccccttggct tcctagagtt     4860

tggacatatt ccaggctaaa tgcttttact caagactaca gaaaggtttg aagtagtgtg     4920

tgcatggcat gcacgtatgt aagtaatctg gggaagaagc aaagatctgt ttcattctta     4980

gcctcaggcc tcatgagggt ctccacaggg ccggagctca ggttacacca ctccttcgtc     5040

cttacaggag atgtagggag aagaatctgc aggctgcttg taggactgtt caccaagggg     5100

gataccagca gcaagagagt gcacccgttt agccctggac cctgtttctt actgtgtgac     5160

ttggctagag ttgggagttc ccccaaaata aacgtgtccc cattttacca gaaccaaacc     5220

tcaacacagc gaagctgtac tgtctttgtg tggcaaagat gttcccttgt aggccccttt     5280

caggtaaccg tcttcacaat gtattttcat cacagtttaa ggagcatcag ccgcttctca     5340

agtgggtagg gaaagcagaa aaacgtacgc aagaggacat ggatccaaaa tgatgatgaa     5400

gcatctccca tggggaggtg atggtgggga gatgatgggc taaacaggca acttttcaaa     5460

aacacagcta tcatagaaaa gaaacttgcc tcatgtaaac tggattgaga aattctcagt     5520

gattctgcaa tggatttttt tttaatgcag aagtaatgta tactctagta ttctggtgtt     5580

tttatattta tgtaataatt tcttaaaacc attcagacag ataactattt aatttttttt     5640

aagaaagttg gaaaggtctc tcctcccaag gacagtggct ggaagagttg gggcacagcc     5700

agttctgaat gttggtggag ggtgtagtgg ctttttggct cagcatccag aaacaccaaa     5760

ccaggctggc taaacaagtg gccgcgtgta aaaacagaca gctctgagtc aaatctgggc     5820

ccttccacaa gggtcctctg aaccaagccc cactcccttg ctaggggtga aagcattaca     5880

gagagatgga gccatctatc caagaagcct tcactcacct tcactgctgc tgttgcaact     5940

cggctgttct ggactctgat gtgtgtggag ggatggggaa tagaacattg actgtgttga     6000

ttaccttcac tattcggcca gcctgacctt ttaataactt tgtaaaaagc atgtatgtat     6060

ttatagtgtt ttagattttt ctaactttta tatcttaaaa gcagagcacc tgtttaagca     6120

ttgtacccct attgttaaag atttgtgtcc tctcattccc tctcttcctc ttgtaagtgc     6180

ccttctaata aacttttcat ggaaaagctc ctgtgccagg agctcagtct gaaaaaaaaa     6240

aaaaaaaaaa aaaaaa                                                     6256


<210>  1751
<211>  1503
<212>  DNA
<213>  homo sapiens

<400>  1751
gtgcagctgc tggcctcgta gacaatcggc tgtctcccca gaagagggaa agaattgtgc       60

agatgagaaa gaggctctca gcgggaggga ggcaggcggg cttgattgac acaggagagg      120

gctggctttt tggagggctc ttagcaacgg ccctggttga gccccctcag ccatgagaaa      180

atcaaatcaa tgtgccattc ttccaggcgc gaggcagcag cggctgcagt tcaacatgaa      240

aggaggcttc ctccctgcct gctaattacc tgctcttccc gatctcatcg tttctgcctt      300

tgcaaagtgc tactgagaag ggggaagaaa cgtccgccac ccatccccct tgctgcctgg      360

gggttcagac ttgattgtga aaccccattg gcttcattgg ctccttgatt taaaccacgc      420

ccggctttct gccctctttg ctgctgctgg gccaggttgc ccagccatat cccagccccg      480

tctgcaggga gccggaggct gctgctgctg ctattgtgtg gatgccgcgc gtgtcttctc      540

ttctttccag agatggctaa caggggcccg agctatggct taagccgaga ggtgcaggag      600

aagatcgagc agaagtatga tgcggacctg gagaacaagc tggtggactg gatcatcctg      660

cagtgcgccg aggacataga gcacccgccc cccggcaggg cccattttca gaaatggtta      720

atggacggga cggtcctgtg caagctgata aatagtttat acccaccagg acaagagccc      780

atacccaaga tctcagagtc aaagatggct tttaagcaga tggagcaaat ctcccagttc      840

ctaaaagctg cggagaccta tggtgtcaga accaccgaca tctttcagac ggtggatcta      900

tgggaaggga aggacatggc agctgtgcag aggaccctga tggctttagg cagcgttgca      960

gtcaccaagg atgatggctg ctatcgggga gagccatcct ggtttcacag gaaagcccag     1020

cagaatcgga gaggcttttc cgaggagcag cttcgccagg gacagaacgt aataggcctg     1080

cagatgggca gcaacaaggg agcctcccag gcgggcatga cagggtacgg gatgcccagg     1140

cagatcatgt aggacgcggc atcctgcccc tggtagagag gacgaatgtt ccacaccatg     1200

gtctctacga aaaagaaata gttagtcacc ttctgacctt ctcctctttc tcaaagcctt     1260

ctgtccctgg tttttgcaag tgctgcattt ccgccgagaa tccgcgttgc ctactgctgc     1320

cacctcctgt tcatttagaa ctatgcaaag actccgcttc cgttttcctg agctcctcgg     1380

gccccagagt ctctgtttga ttatttattt atttatttat ttatttgcca aaaattctcc     1440

tcttcaactt atagaatgca cctaataaag taattagtct tgtgtcttaa aaaaaaaaaa     1500

aaa                                                                   1503


<210>  1752
<211>  2619
<212>  DNA
<213>  homo sapiens

<400>  1752
aggccctggg acctcccggt cccttgcctg cttccggctt tcgctcgctt ccatatccgc       60

tcctctagtc gccctccgct ggccccgcct tcgtccccgg aagattgggt cttctggcga      120

gccactgttt gccgtttgat cgggcaccaa ataaagtttc tttattcaaa agcacttttt      180

ttttaaagcc acaccacccc cattctcagc tcctccttcg cggcggtacc gcctctgttt      240

ctgcggcgat tgaacagccg agctttgcgg ccgggatcgc ggaaagtgat ggctgtcgtc      300

ccggcgtctc tctcaggaca ggacgtggga tcatttgcat atcttacaat taaagacaga      360

ataccacaga tcttaactaa ggttattgat acattgcatc gacataaaag tgaatttttt      420

gagaaacacg gagaggaagg cgtggaagct gaaaagaaag ctatctctct cctttctaaa      480

ttacggaatg aattgcaaac agataaacca tttatcccct tggttgagaa atttgttgat      540

actgatatat ggaatcagta cctagaatat caacagagtc ttttaaatga aagtgatgga      600

aaatcaagat ggttctactc accgtggttg ttggtagaat gttacatgta tcgaagaatt      660

catgaagcaa ttatccagag tccaccaatc gattactttg atgtatttaa agaatcaaaa      720

gagcaaaatt tctatgggtc acaggaatcc atcattgctt tatgtactca cctgcaacaa      780

ttgataagaa ctattgaaga cctagatgaa aatcagctga aagatgagtt ttttaaactt      840

ctgcagattt cactgtgggg aaataagtgt gatctgtctc tctcaggtgg agaaagtagt      900

tctcagaata ccaatgtact aaattcattg gaagacctaa aacctttcat tttattgaat      960

gatatggaac atctttggtc attgcttagc aattgcaaga aaacaagaga aaaagcttct     1020

gctactagag tgtatattgt tctcgataat tctggatttg agcttgttac agatttaata     1080

ttagccgact tcttgttgtc ctctgaactg gctactgagg ttcattttta tggaaaaaca     1140

attccatggt ttgtttctga tactactata catgatttta attggttaat tgaacaggta     1200

aaacacagta atcataagtg gatgtccaag tgtggggctg actgggaaga gtatattaaa     1260

atgggtaaat gggtttacca caatcatata ttttggactc tgcctcatga gtactgtgca     1320

atgcctcagg ttgcacctga cttatatgct gaactacaga aggcacattt aattttattc     1380

aagggtgatt tgaattacag gaagttgaca ggtgacagaa aatgggagtt ttctgttcca     1440

tttcatcagg ctctgaatgg cttccatcct gcaccactct gtaccataag aacattaaaa     1500

gctgaaattc aggttggtct gcagcctggg caaggggaac agctcctggc ctctgagccc     1560

agctggtgga ccactggaaa atatggaata tttcagtacg atggtcccct ttgacttgat     1620

ttaggagctc tcagttgcat agaaagatct ggtgagcacc ttttcatccc cagaaaagga     1680

gcacgtgaat tgagtcgcct ggcggctctg tacgcgctca gggaagctta gcttcttggt     1740

gcccatctac gtgcactgga tgatttttct tttgaacatt ttgccccact acactgtttt     1800

ggggatagct gggttaagca agttaaagat atttacattt atattggaat tttagcaact     1860

ttttttcagg ttaaatatat aatttcaagt gcttttaatg aacttatttt taattggcta     1920

gggagcaaaa aataagtgag ttctgctttt agttagttaa ccttgttctt ttcttaaata     1980

gtacactgca tggtatttaa tattccagga agcatgggat tttattttgc ttgattttgg     2040

gcacatgaaa taatagctct aggaaaatgc gcatcttaat gactctttgt aaagagaggc     2100

atttcttaca actgtgatgt ttgcttacat aaaagttacc tcataagtta attctaactt     2160

ttattcttga attttatttc atttcaatag cttgtttcat ttgcacgcct ttgtattttg     2220

attgacctgt agaatggatg ttaggaaact caaaattgaa cacagtgaaa caaatggtat     2280

ttgaagaaat gtaatatctt ttatattcta tttatgatat ccataatcaa atgagattat     2340

tttaccacat aaatgtttta aatatcagat ttttagtttg cagttttagg aaaatgcttt     2400

agatagaaaa ggttcttatg cattgaattt ggagtactac caacaatgaa tgaatttatt     2460

ttttatattc ttacacattt tattggtcat tgtcacagat agtaaatact aaaaatttca     2520

ggtcagtttg ttttgaaact gaaattggaa ataaatctgg aaatgttttg ttgcactaaa     2580

ataataaaat gaattgtact gaaaaaaaaa aaaaaaaaa                            2619


<210>  1753
<211>  3419
<212>  DNA
<213>  homo sapiens

<400>  1753
gcacgcacgc acgcacgcca gcggccggcg gggccgcagg ctcgcgcccg ggctcgcccc       60

gcgccgctcc agaggctcgc gcactcagca ggttgggctg cggcggcggc ggcagctgtg      120

gaagctcagg cgctgcgcgt gagaggtccc agatacgtct gcggttccgg ctccgccacc      180

ctcagcttct cttccccagg tctgggagcc gagtgcggaa ggagggaacg gccctagctt      240

tgggaagcca gaggacaccc ctggctcctg ccgacaccgc cctccttccc ttcccagccg      300

cgggcctcgc tcggtgctag gctactctgc cgggaggcgg cggcggctgc cagtctgtgg      360

agagtcctgc tgccctccag ccgggctcct ccaccgggcc ttgcaggggc cgagagagct      420

cggtgcccgc ccttccgctc gcctttttcg tcagctggct ggagcagcat cggtccggga      480

ggtctctagg ctgaggcggc ggccgctcct ctagttccac aatgtccacg ggcggagact      540

tcgggaatcc gctgaggaaa ttcaagctgg tgttcctggg ggagcaaagc gttggaaaga      600

catctttgat caccagattc atgtatgaca gttttgacaa cacctatcag gcaacaattg      660

gcattgactt tttatcaaaa actatgtact tggaggatcg aacagtacga ttgcaattat      720

gggacacagc aggtcaagag cggttcagga gcttgattcc tagctacatt cgtgactcca      780

ctgtggcagt tgttgtttat gatatcacaa atgttaactc attccagcaa actacaaagt      840

ggattgatga tgtcagaaca gaaagaggaa gtgatgttat catcatgcta gtaggaaata      900

aaacagatct tgctgacaag aggcaagtgt caattgagga gggagagagg aaagccaaag      960

agctgaatgt tatgtttatt gaaactagtg caaaagctgg atacaatgta aagcagctct     1020

ttcgacgtgt agcagcagct ttgccgggaa tggaaagcac acaggacaga agcagagaag     1080

atatgattga cataaaactg gaaaagcctc aggagcaacc agtcagtgaa ggaggctgtt     1140

cctgctaatc tcccatgtca tcttcaacct tcttcagaag ctcactgctt tggccccctt     1200

actctttcat tgactgcagt gtgaatattg gcttgaacct tttcccttca gtaataacgt     1260

attgcaattc atcattgctg cctgtctcgt ggagatgatc tattagcttc acaagcacaa     1320

caaaagtcag tgtcttcatt atttatattt tacaaaaagc caaaatattt cagcatattc     1380

cagtgataac tttaaaaatt agatacattt tcttaacatt tttttctttt ttaatgttat     1440

gataatgtac ttcaaaatga tggaaatctc aacagtatga gtatggcttg gttaacgagc     1500

ggtatgttca cagcctactt tatctctcct tgcttttctc acctctcact tacccccatt     1560

ccctattacc ctattcttac ctagcctccc ccgacttcct caaaacaaac aagagatggc     1620

aaagcagcag ttctaccaag cccattggaa ttatccttta attttacaga taccacttgc     1680

tgtaggctac ggaccaagat gtccaaaatt attcttgagc actgatataa attacggtct     1740

tctttgaggt caaaattcag ccatcatggt aggcagtgct tgaatgagaa aaggctcctg     1800

gtgcatcttc aaaatgagtc ctaaagaaca tactgagtac ttagaagtag aagaacataa     1860

gatgtatttc tgactaaaac aaatggctct ttcacatgtg ctttattaga ctctgggaga     1920

gaaaattaac caagtgcttc agaacaggtt tttagtattt aattcttcac ggtaagaaaa     1980

tgaagttcta atgaactgtt tctcccaagg ttttaaaatt gtcaagagtt attctgtttg     2040

tttaaaaaat aagaaacctc tttaagcaat agattttgct tgggttttct tttttaaaaa     2100

cataatactg tgcaggcaag gcactgtaaa agttttaatt ccttccagaa gaaccagtgg     2160

aagaatttaa atttggcgct acgatcaaaa ctactgaatt agtagaaata atgatgtcta     2220

aagcttacca acaaaagaac cctcagcaga ataacaaaaa ctttgctcag gacatttgag     2280

gtcaaattga agacggaaac cggaaaccgt tttcttgtaa gcccctagag gcagatcagg     2340

taaagcatac atagtagagg gaaaggagag aatggaaata aaactcaata ttatgcagat     2400

ttatgcctta ttttttagca ttttttaagg ttgggtcttt caggctggtt ttggtttgta     2460

ttagatctgt atagtttaat taactggtga tttagtttta tatttaagct acaattaatc     2520

ttttttcttt ggtgatattt atttctttgc cttttttttt tttaacaact ttcaatcttc     2580

agatgtttcg ttgaatctat ttagagcttc accatggcaa tatgtatttc ccttaaaaca     2640

ctgcaaacaa atatactagg agtgtgccct tttaatcttt actagttatt gtgagattgc     2700

tgtgtaagct aataaacaca tttgtaaata cattgtttgc aggacgaaaa cttctgagtt     2760

acagctcagg aaaagcctgc tgaatttatg ttgtaagcat tacttaacac agtataaaga     2820

tgaaaagaca acaaaaatat cttcatactt cctcatcccc tcattggaac aaaaccttaa     2880

actgggagaa ccttagtccc ctctctttcc tcttcctcct ccacttccca cttattgtca     2940

ccttgtaata ttcagagagc acttggatta tggatctgaa tagagaaatg cttacagata     3000

atcattagcc cacataccag taacttatac ttaaagatgg gatggagttg taaagtgctt     3060

ttataataca atataattgt taaaggcaag ggttgactct ttgttttatt ttgacatggc     3120

atgtcctgaa ataaatattg attcaatatg gcagatgggt catattcttt atttggaaga     3180

agttgtgact tctgacatgg gtgtgattgt cttcctacac tgttgcattt gattcttttt     3240

atgtattttt aagaaagtaa ccagttatac tgcttttaat attgattggt ctttttattt     3300

ggcttggagt tcttcaaagc attgaagtgt gttcatagtc caggtttttt ttttaataaa     3360

cacaattttg ctgccaaaaa tatataaata aaacacgaaa gaaaacaaaa aaaaaaaaa      3419


<210>  1754
<211>  3529
<212>  DNA
<213>  homo sapiens

<400>  1754
taagaaacga cacacagatt aggcagtgct actcttctta aatctctcat ttgtttccta       60

ggttccctgg ttgtgaaaat acatgagata aatcatgaag gccactatca tcctccttct      120

gcttgcacaa gtttcctggg ctggaccgtt tcaacagaga ggcttatttg actttatgct      180

agaagatgag gcttctggga taggcccaga agttcctgat gaccgcgact tcgagccctc      240

cctaggccca gtgtgcccct tccgctgtca atgccatctt cgagtggtcc agtgttctga      300

tttgggtctt cctccttccc ttacggaatt acatcttgat ggcaacaaaa tcagcagagt      360

tgatgcagct agcctgaaag gactgaataa tttggctaag ttgggattga gtttcaacag      420

catctctgct gttgacaatg gctctctggc caacacgcct catctgaggg agcttcactt      480

ggacaacaac aagcttacca gagtacctgg tgggctggca gagcataagt acatccaggt      540

tgtctacctt cataacaaca atatctctgt agttggatca agtgacttct gcccacctgg      600

acacaacacc aaaaaggctt cttattcggg tgtgagtctt ttcagcaacc cggtccagta      660

ctgggagata cagccatcca ccttcagatg tgtctacgtg cgctctgcca ttcaactcgg      720

aaactataag taattctcaa gaaagccctc atttttataa cctggcaaaa tcttgttaat      780

gtcattgcta aaaaataaat aaaagctaga tactggaaac ctaactgcaa tgtggatgtt      840

ttacccacat gacttattat gcataaagcc aaatttccag tttaagtaat tgcctacaat      900

aaaaagaaat tttgcctgcc attttcagaa tcatcttttg aagctttctg ttgatgttaa      960

ctgagctact agagatattc ttatttcact aaatgtaaaa tttggagtaa atatatatgt     1020

caatatttag taaagctttt cttttttaat ttccaggaaa aaataaaaag agtatgagtc     1080

ttctgtaatt cattgagcag ttagctcatt tgagataaag tcaaatgcca aacactagct     1140

ctgtattaat ccccatcatt actggtaaag cctcatttga atgtgtgaat tcaatacagg     1200

ctatgtaaaa tttttactaa tgtcattatt ttgaaaaaat aaatttaaaa atacattcaa     1260

aattactatt gtatacaagc ttaattgtta atattcccta aacacaattt tatgaaggga     1320

gaagacattg gtttgttgac aataacagta catcttttca agttctcagc tatttcttct     1380

acctctccct atcttacatt tgagtatggt aacttatgtc atctatgttg aatgtaagct     1440

tataaagcac aaagcataca tttcctgact ggtctagaga actgatgttt caatttaccc     1500

ctctgctaaa taaatattaa aactatcatg tgacttcatg taatcaggct gaacatttct     1560

acaattacta gatgtattag acgtaagtat tttctttagt taaaccaccc atgttagaaa     1620

tgttttctgt agaatttata aacaactatc aatgcagaca atttaataag cctggggatg     1680

atttacttac agtaaacatt tatcaaattg tacatttgtg ctatcaacaa ttaataagca     1740

aatatgtgaa aatagtttct gtcttctatg aagttagata tttgatggtt aaaaccccta     1800

taaatcatag tttcatatgg gaaaaaataa ttgaaataca gtgtaaattt aaataattta     1860

ttaagtatag caaataattg aaatatggtg gactaaattt tgtcatagaa atatgtgcaa     1920

gttatagtag tggctcacat gagaggtaat caattctgct aatagtagca gaatgagtgc     1980

agtggaacat gaaaaacttg aggagataac agttgaggtg ggtttccata gatgcataat     2040

agttcaagag caagatttgg tggggaggca ctattcaaga cagggactaa gttcaaaatc     2100

caagacgtat gctgggacac acctctgaca ggttggcata aaggaggctt aatcaaacta     2160

tttttcttct tctgaaacag aagcaataat tttcatttac atttgacata tcccgaggta     2220

atattaacat tagggaaagt tactcttttc catctttcca cattcttgca ggaccataaa     2280

atctgaattt tccagtattt ttaataagag ggaagaaacc tctctttttc ttctcttttt     2340

catctcccaa gagatcctcc tctcatgact acagttgaat aggtggtttc tattggaaga     2400

cattcaggaa ttcaaggtgc atgtccataa atggactttt tttgttgttg ttcagagctg     2460

gaccttgaat gatgcatcct tctctctgtt gtaaccatga ataatgcacc cttcatgcta     2520

tagcctttaa cgattcaccc ttcttattgt aaccttgaat gattcaccct ttatggtgta     2580

gccttgagtg acgcaccctt catgttgtag ccttcaatga tgcacactcc atgttatagc     2640

cttgaatgat atacccttta tgctgcagcc tttctcttat ggggaaaagc ctgcagatat     2700

cctgctgctt aactgacaag tgtggtgaga aataagtaga aatctaaaga ggggaagacc     2760

attttggaca cttatctgca aggcagatcc aacacacttt tccagtagtc aagctacttc     2820

taattttgtt cagtatcaaa atgagaaaca ggcctgattc tccagcactc ttgtcaacac     2880

aacttccccc catatttata tatatacaca cacatatata tctttatata tatacacaca     2940

tatatatctt tatatatata tatttatata tatatctttt tgcatatata catatatatg     3000

tatctttatt tcctttgaaa taaagataaa tatagctgat ttctttggct tcgacactta     3060

ctatttgcat gactaaggga agctagttaa cctttctgtg actcatttcc ttgtccataa     3120

aatgggaata ttaattgtac atgtcttatg gattggtgtg tgaattcagt tagcgagtgt     3180

agaatataac ttatagatca aagtagagta aatggaaagg gctcaactat ggtgttgcta     3240

ctgccattgt tattacaggc acacagttcg agctataatc atttcaaggg aaattcttat     3300

gtgtcagttc tggatcgagg tctgagattc tgcatttcaa acaaacttcc aggaatgctg     3360

ctgcttcttg gtccacactt ggagaaataa gtcagcagag agtcctctcg tttcctattg     3420

taccatgtct gtcttttgtc tcctgcttat tggcctctgt aaggaactca cagctgctat     3480

aataaagtac caaaaactgg gtggcttaaa acaaaaaaaa aaaaaaaaa                 3529


<210>  1755
<211>  10978
<212>  DNA
<213>  homo sapiens

<400>  1755
atggtggagc cagggcaaga tttactgctt gctgctttga gtgagagtgg aattagtccg       60

aatgacctct ttgatattga tggtggagat gcagggcttg caactccaat gcctaccccg      120

tcagttcagc agtcagtgcc acttagtgca ttagaactag gtttggagac cgaagcagca      180

gttcctgtta aacaagaacc agagactgta cctactccag cactattaaa tgtgaggcag      240

cctccatcta ctacaacatt tgtgctgaat caaataaatc atcttccacc cttgggatct      300

acaattgtaa tgactaaaac accacctgta acaaccaaca ggcaaaccat cactttaact      360

aagtttatcc agactactgc aagcacacgc ccgtcagtct cagcaccaac agtacgaaat      420

gccatgacct ctgcaccttc aaaagaccaa gttcagctta aagatctact gaaaaataat      480

agtcttaatg aactgatgaa actaaagcca cctgctaata ttgctcagcc agtagcaaca      540

gcagctactg atgtaagcaa tggtacagta aagaaagagt cttctaataa agaaggagct      600

agaatgtgga taaacgacat gaagatgagg agtttttccc caaccatgaa ggttcctgtt      660

gtaaaagaag atgatgaacc agaggaagaa gatgaagaag aaatgggtca tgcagaaacc      720

tatgcagaat acatgccaat aaaattaaaa attggcctac gtcatccaga tgctgtagtg      780

gaaaccagct ctttatccag tgttactcct cctgatgttt ggtacaaaac atccatttct      840

gaggaaacca ttgataatgg ctggttatca gcattgcagc ttgaggcaat tacatatgca      900

gcccagcaac atgaaacttt cctacctaat ggagatcgtg ctggcttctt aataggtgat      960

ggtgccggtg taggaaaagg aaggacgata gcaggaatca tctatgaaaa ttatttgttg     1020

agtagaaaac gagcattgtg gtttagtgtt tcaaatgact taaagtatga tgctgaaaga     1080

gatttaaggg atattggagc aaaaaacatt ttggttcatt cgttaaataa gtttaaatac     1140

ggaaaaattt cttccaaaca taatgggagt gtgaaaaagg gtgttatttt tgctacttac     1200

tcttcactta ttggtgaaag ccagtctggc ggcaagtata aaactaggtt aaaacaactt     1260

ctgcattggt gcggtgatga cttcgatgga gtgatagtgt ttgatgagtg tcataaagcc     1320

aaaaacttat gtcctgttgg ttcttcaaag ccaaccaaga caggcttagc agttttagag     1380

cttcagaaca aattgccaaa agccagagtt gtttatgcta gtgcaactgg tgcttctgaa     1440

ccacgcaaca tggcctatat gaaccgtctt ggcatatggg gtgagggtac tccatttaga     1500

gaattcagtg attttattca agcagtagaa cggagaggag ttggtgccat ggaaatagtt     1560

gctatggata tgaagcttag aggaatgtac attgctcgac aactgagctt tactggagtg     1620

accttcaaaa ttgaggaagt tcttctttct cagagctacg ttaaaatgta taacaaagct     1680

gtcaagctgt gggtcatcgc cagagagcgg tttcagcaag ctgcagatct gattgatgct     1740

gagcaacgaa tgaagaagtc catgtggggt cagttctggt ctgctcacca gaggttcttc     1800

aaatacttat gcatagcatc caaagttaaa agggttgtgc aactagctcg agaggaaatc     1860

aagaatggaa aatgtgttgt aattggtctg cagtctacag gagaagctag aacattagaa     1920

gctttggaag agggcggggg agaattgaat gattttgttt caactgccaa aggtgtgttg     1980

cagtcactca ttgaaaaaca ttttcctgct ccagacagga aaaaacttta tagtttacta     2040

ggaatcgatt tgacagctcc aagtaacaac agttcgccaa gagatagtcc ttgtaaagaa     2100

aataaaataa agaagcggaa aggtgaagaa ataactcgag aagccaaaaa agcacgaaaa     2160

gtaggtggcc ttactggtag cagttctgac gacagtggaa gtgaatctga tgcctctgat     2220

aatgaagaaa gtgactatga gagctctaaa aacatgagtt ctggagatga tgacgatttc     2280

aacccatttt tagatgagtc taatgaggat gatgaaaatg atccctggtt aattagaaaa     2340

gaccacaaga aaaacaaaga gaaaaaaaag aagaaaagta tagatccaga ttctattcaa     2400

agtgccttat tagcatcagg tcttggatca aaacgaccta gtttttcatc tacaccagtt     2460

atctcacctg ctcctaacag tacaccagct aacagtaaca ccaacagtaa cagtagcctt     2520

ataacaagtc aggatgctgt ggaaagggct cagcagatga agaaagacct gcttgataag     2580

ctagaaaaat tagctgaaga cctcccccct aataccctgg atgaacttat cgatgaactt     2640

ggtggccctg agaacgttgc tgagatgact ggccgcaagg gacgggttgt gagcaatgat     2700

gatggaagca tatcttatga gtcaagatct gaacttgatg tgcctgtgga aatactaaac     2760

atcacagaaa aacaacgatt tatggatgga gataagaata ttgctatcat ctcagaagct     2820

gccagctcgg gtatttcatt acaagcagat aggagagcta aaaatcaaag gcgaagagtt     2880

catatgactt tagaattacc ttggagcgct gatagagcaa ttcaacagtt cggacgtact     2940

catagatcaa accaagttac tgctcctgag tatgtctttc tgatatctga actggcagga     3000

gaacaaagat ttgcatctat tgttgctaaa agacttgaga gtttgggggc acttacacat     3060

ggtgatagaa gggcaacaga atctagagat ctgagcaggt tcaactttga taataagtat     3120

ggaagaaatg ctttagaaat tgtcatgaaa tccattgtaa acttggattc tcctatggta     3180

tcaccacctc cagactatcc tggagaattt tttaaagatg ttcgacaagg actgataggc     3240

gttggcctga taaatgtaga agatcgctcg ggaattctta ctctcgataa agattataac     3300

aacataggaa aattcttaaa tagaatttta ggcatggagg tgcatcagca gaatgcgtta     3360

tttcagtatt ttgcggacac acttactgca gttgttcaaa atgccaaaaa aaatggaaga     3420

tatgatatgg gaatcttaga tcttggttct ggagatgaaa aagtgcggaa aagtgatgtt     3480

aaaaagtttc tgactccagg atattcaacc tctggccacg tagaattata cacaattagt     3540

gtagagaggg gaatgtcatg ggaggaagct accaagattt gggctgagct gacaggacca     3600

gacgatggct tttacttgtc attgcaaata aggaacaaca agaaaactgc catcttagtt     3660

aaagaagtga atcctaaaaa gaaacttttc ttagtttatc gaccaaatac tgggaagcag     3720

ctcaaattag aaatttatgc tgatctaaaa aagaaatata agaaggtcgt ctcagatgat     3780

gccctgatgc actggttaga tcagtataat tcatctgcag atacttgtac tcatgcttat     3840

tggcgcggca attgcaaaaa agcaagcttg gggctagttt gtgaaatagg tcttcgttgc     3900

cgtacatatt atgtattatg tggttcagtg ctgagtgtct ggacaaaagt tgagggtgtt     3960

ctagcatctg tcagtggcac aaacgtgaag atgcagatcg tgcggctaag aacggaagat     4020

gggcaacgga ttgtaggttt gatcattccg gcaaattgtg tgtctcctct tgtaaatctc     4080

ctatcaactt cagaccagtc tcaacagctt gcggtccaac agaaacagct atggcaacag     4140

catcaccctc agagcatcac caacttgagc aacgcatgaa gaacagacag gtttcaacat     4200

ggatggatct gaaatgctgt tgaagcatat catttgcata aaaatcaggg acagtttcca     4260

aagaattata tatttttttc agttgtgctc tctagttagt ttttttggga gtaaggacaa     4320

acctggaata gatagcaaaa ctgaaaatca gcagtgctga tggtggtaca tatgtctttc     4380

ctttagcttc tcccctgata attcccatct gcttttactt cgggtgagca gagggggatg     4440

tgtgtgtgcg tgtgtgtcag tctgtttgtg agtgtgttaa aggctacaga ccacagttgg     4500

tttaaaatgc ttggaacttc ccaaactggc tttactttat gtttatacag tgctcagggt     4560

taacgcagta catccatgcc attgctgtgg gaggtatccc cggatgcatg tgttttgagt     4620

ctataaatat agaaaatata tattggtttc tttttccaac ttaataggtt tattaaagca     4680

tgaaatgaaa ggttgcatat catgcattca ggttattttc taatttttgt tctgacagtg     4740

catgtctttg gaagcatgct gaaacaagat taacacagga gtcgagtaac agagagaaac     4800

atttgttaga tgtacagcat tggttattgc atttttatag tgtttatacc tgggtattgc     4860

ttcaaaccct gcagacccct ccttcccctt ctccctgccc tgggtttctg gtcaaggtaa     4920

tgaatacata catttttctg tgataaaact cttaaaagtt aattttaatg tattaatagt     4980

attcctaatg tgtgctgcag aaatggctat gagcctctta aatttacatt tgcaacttaa     5040

aggtagtttt agaaggaagt acaaattggc tttcatcttg caaacaatcg ttttttactt     5100

cattatctta atttgctttg tcactcataa aaaggaaacc atacctgagt tgtagacaat     5160

gaggaaacac ttgaggcttc tgctgtgtgt tcttttgtta ttgttgttat tgttgttact     5220

cagtaacttg aatattgttt aatgtgttgt aagacgtaga gtttatctca agctgttaaa     5280

aatggtaatg tacaaatgtg aatagacact tatctatata atatgggtaa gttttgtttc     5340

gcctataata gatgtttata aaaacaagtg aggggacagt tggtcttttt atcttttctt     5400

tctttttctt tcttttcttt ttttcttttt tttttttttt tttttttttt ttgcttccac     5460

aggttgcact attgaaaaat cgagattgta taaacctggt aaaaagctgc aagatgccaa     5520

aatcttgtag atgtcaaata aaaagttatt atactaacaa gaagtggact cttgtttagg     5580

ccctcactgg tgaccttcag aagtagtctg tgacggggac tcagcagaat ttgtgtgttg     5640

tctcagcatt ccaggtagcc ttatagtttg gcttaaaact tatccctaaa atgtaagatg     5700

gcattgaggg aaagggtata atgatagtac ttctgaatgt tttttaagtt gaattgtttg     5760

taaacttctt gcagaattgg gtgagatgtg tgttaaaact gacaaacctg gctgaaagct     5820

tagggcgttc atcctcttgt gtctccttta gcctgagttt ggttatgtca agcttaccgt     5880

aagttttctt aggatttatt tattcttggt gcctaaaaga ataaattgaa agtactttct     5940

gttctttggc acattttgcc cagcggatgc aacttctatc ctcagtccag ttcatatatc     6000

tcaggcagtg atccattttg tatcagccag tttcccttgt tagggccgct agacccggct     6060

ggcagccaag agcagcactc tccccacctt cagcagaact tctcagctca tgtgtgtgtt     6120

tttaaaagca gtaggcagct tccatcagca atggaagtgt cccccactcc agtggtggag     6180

gtgcagtcgc tggacctgag gaagtgggga agcattacaa accctcctgc agtaagaatg     6240

gcagagttgg gaaggatctt ctctcgcagg ctgttggccc aactcctctt ttctgtgtat     6300

gagggcatct tagtttttta tggcgttttc aaagcagcat atgaggattc ttagcatgca     6360

gctaagtgac aacccccatg gcctatgatg taatgtttgc tctggactag ccatcttgat     6420

aaataggagt gtatgtatct taggttcttt gtagaacagc tatttttttt tctcattaaa     6480

aaggcctctg aaagccctct caaaatggac ctcacaaagg caaccagtgt gaatggatgg     6540

gagctggggt gctgcatgcc caggctggtc atggtgtgtg cagcacccag agagttgcac     6600

ccaccccttc ttcaggtgga catccgacct ttacactgtg gtcttgcaaa aatcagcgag     6660

ttagtttggc cgccctgtga agcttcagca ttcaaggtcc tcttctgtta aaacccaact     6720

cgtagccggg cgtggtggct cactcctata atcccagcac ttcgggaggc caaggcaggt     6780

gcatcacttg aggccaggag ttcgagacca gcctggtcca catggcaaaa ccccatctgt     6840

accaaaaaat acaaaaaatt tgccgctgac ttctgtaaaa taggtccatt cattgcagga     6900

tctaaatgcc acacctgaat tcagaggcct tgtttaatta accccatgtc cactttgcct     6960

ctgcaatgcc tttttctttt tagcaatatg gctctgagca caaagatttg gttggaaatc     7020

atgttcgtgt tttcagagtt tacagcgtca attgtactga aaaccacttc cagagtctaa     7080

agcagctcag atgttatctc tgggggaatt agtgttcccc tcatttagca acctccatac     7140

cacaaggtct ctgtctgtag ttactgggat tatccagata cactatcaat gatacaaatt     7200

cataggagta ttaatgcatt tctttaaaca caacttgatt aagaagcaaa tatgttaagc     7260

agttttcttt ttctgctgct aaattacagt tagacacttc agtatcttct ctttacatgt     7320

gtatataaat tagtaagaac ctgcatccaa agcaatgtag tgtgtgtatg tatctatata     7380

tatttattct aactcagcac ttcagaagcc tttttgagtt acaacaatat tttagtttgc     7440

ctcatctgta gaggtaaaat ttctatatta ccaagctcca gaggaatatg atattttaca     7500

ggcacaattt tctggctgta gtccctgggg cattcatttg ctggcctcca tgggatgctg     7560

ttagaacaat tgttagccgg caagagaaga aaggctacca ggacagcatt tataattgta     7620

gaatgggagc cttcttccct ctcccctcca ctttcatttt agcatgagat aaaaaaatag     7680

attggaaatg attgttgcat ctcacttcat ggaagtaggg gcagaagttc cctctggatc     7740

cttttcttga caagcagtca agaggaaggt ccccatacac atgtacctgt gtgatacttg     7800

gtagtttcta agaatggtgc tacataagcg ttgctgttag gctgggatcc tattaatgaa     7860

cgtttgatta gttcaggcct cccaatggca aaggcagaca ccgtggagat ggacatttac     7920

tgactcccct tctgtgtggc ttcggtctcc ctggctaaca ccacacctgt gcgtactgcg     7980

ctcggcccac tttgctgcag aaacgtagca agcgtttcat gtcagggcta cagctgagag     8040

caaaaactgc aaaaaaaaaa aaaaatgtct cattgaatgc cagttgtctg atacaaatgc     8100

agtgtctttt aagtgacaga aacacaccta aatacctgca actcaagctc gctagcattt     8160

tttttttgag tacttgagat aaaatccaaa acccaccctc taattttgtg ctgtatttat     8220

atatatgtac ataaatgtat atatagagaa atgttgagtt cttctggatt ctgaatgtaa     8280

ataattcttg taaattggga ctctgcccac ctgtttctcc cttttccctc ttcccttcag     8340

ctctatttat tcttttcttg actttcccat atggggcatc ttatgacttt tttttttttt     8400

tttttttaag aaaagtatgg aaaacttttc atttagaaaa gtatttgttc ctgtatttta     8460

gaattcagtt ttgcatcttt gctgtagaat tcctgttttg tgttaatgtt ttttactatg     8520

tcttattgtg ttgtgtgcaa tgcattgtac tggggggatg cacttgagtg ccatttctga     8580

tactgtcatt gtatgactgc tgatgctcgt ttatgttgtt ctttggaagc tatagtgagc     8640

ctgatgtttt cacattttaa aaaatgcttc ctgagacttc tttaagctcc tctaacttct     8700

tcagtgcatt tgggatcaaa cttagctctt agatcagcaa acctgacttg cttctacttt     8760

tgcaattttt caggccttac catatttctt atctctgtct tcccacctga taggaaaatc     8820

ttgcagattt gaaacagtgg tttctggcct gctgctgcag caaattccct atgtttattt     8880

aagaagtcgg gcctatgctt ttaacctaca aatgatgagt aatttacttg caatgaacac     8940

aggtagcctg ctgctgttta taacctgttg aggatattta tagcaggcag gaggcaggcc     9000

tagtgtgtta ttgacaggtg actttagaga atgtacattg gccgggtgcg gtggctcacg     9060

cctgtaatcc cagcactttg ggaggccgag gcgggcggat catgaggtca ggagattgag     9120

accatctcct ggctaacacg gtgaaacccc gtctctacta aaaatacaaa aaaaaaaaaa     9180

acttagccag gcgtggtggc gggtgcctgt agtcccagct actcaggagg ctgaggcagg     9240

agaatggcat gaacctggga ggcagagctt gcagtgagcc cagatcgcgc cactgcactc     9300

cagcctgggc aacagaccga gactccgtct cgaaaaaaaa aaaagagaga gaatgtacat     9360

taaggaacaa ttgtcctcca aaagagagcc aagcaactgc tctggagcct cctaggctga     9420

ctctgctgga gggtgagaca agcagattcc cattgcagca ctggtccctg gggtaccctg     9480

aacggctgtg ctctccaccc ttgtatcggt gagtggatct tgtctacatc agccgtaagc     9540

ctagaagcag agcgggatcg aggcgttttt aataattcga gttgggaaga cccggatggt     9600

tcatcaaaat gatggtgttg agcacccggg aggcagacat tgggtatttg ttcacaattt     9660

tgcacctgta agaaaatgtt cctttataac tttcaaggat tgccgtgagc gtctttgggg     9720

ccttttcatt catgtacaag tttcattcat tactattcaa cttggtagac ttggtgaaaa     9780

atgtaaaagc attctgtatt tggatcagtc ttgggaacta aatttgtcgt gaattggggc     9840

ctgtcacaga ttgcctccag tgtgcatcct ccacgcagac cctccttgct cagtctccct     9900

ctggcgccca tggggaagcc gtgctgtggt tggcagtgcg gccatctggg ctgccgcaac     9960

gtggcagggc accgtccagc aagactgccc cttagtgcag ggctaagcaa ggaaaagaag    10020

aagcccaaaa aggcgggttc tttttgatac ttgtaattca ggcgtcctcc agagtgaagg    10080

ccactctgca ggcccctggt gagaacctgt ctggcttttc cactgcgggc ccctaaccag    10140

taccctgccc ttgtggccca tttgtgcctg ggcagatgtt tctggccagc agacactgaa    10200

ggcctttttg ctgtgacagt atttatggca ctgaagagga taaagaagct tgagccctct    10260

ttctgactcc cactttatgg ggcagagaga gctttttttc tacatagcac attgcagtct    10320

caccgctatc agaaaaatat cctgttcatg gtttatactg aatttgcaaa ctactgatat    10380

gatttttcaa taaccacttg tatcttccat catccatgag aggtgggaag aggtacactg    10440

tatctctgca ataaaacttt ggccaggttc tacctcctct gagcaaagga tacttttcta    10500

tgtaggtgta gatggttctc ctttactaat ctgacatggt gcatctggag acaacatctg    10560

atgggatcca aagacaactt gaaacaaagg tggatgtcag ctcttggtgt gttttcattt    10620

ggttctcttt tttaaatctc ccttttgtta tcgctcctgt tgtagcgtgt ccatcagtgt    10680

gtgaagggtg cgccctgttc caatgatact gcattgctgc atccagcctt tcgtgggagc    10740

acggtaccaa gcgtccggaa ttgattatcc caatcatttt tgatatgtaa ctgaaaaatt    10800

tggtctcatg caataaaaat gtactggctg cattttagca aggtttattt actcttgcaa    10860

gtaaaaacga tcaaccgtga agcgtaacaa attctgtatt tagttttttt ttctgttgtg    10920

gtggtttttg ttttgttttt tgtttttgta agattctaaa taaattaaat acgagtca      10978


<210>  1756
<211>  2403
<212>  DNA
<213>  homo sapiens

<400>  1756
aactgagttc aaggcaatta aagtcaagag ctaaggaggg agggagaggg tttagaaata       60

ccagcataat aagtagtatg actgggtgct ctgtaaatta actcaattag acaaagcctg      120

acttaacggg ggaagatggt gagaagcgct accctcatta aatttggttg ttagaggcgc      180

ttctaaggaa attaagtctg ttagttgttt gaatcacata aaattgtgtg tgcacgttca      240

tgtacacatg tgcacacatg taacctctgt gattcttgtg ggtatttttt taagaagaaa      300

ggaatagaaa gcaaagaaaa ataaaaaata ctgaaaagaa aagactgaaa gagtagaaga      360

taaggagaaa agtacgacag agacaaggaa agtaagagag agagagagct ctcccaatta      420

taaagccatg agcccccttt ggtgggggtt tctgctcagt tgcttgggct gcaaaatcct      480

gccaggagcc cagggtcagt tcccccgagt ctgcatgacg gtggacagcc tagtgaacaa      540

ggagtgctgc ccacgcctgg gtgcagagtc ggccaatgtc tgtggctctc agcaaggccg      600

ggggcagtgc acagaggtgc gagccgacac aaggccctgg agtggtccct acatcctacg      660

aaaccaggat gaccgtgagc tgtggccaag aaaattcttc caccggacct gcaagtgcac      720

aggaaacttt gccggctata attgtggaga ctgcaagttt ggctggaccg gtcccaactg      780

cgagcggaag aaaccaccag tgattcggca gaacatccat tccttgagtc ctcaggaaag      840

agagcagttc ttgggcgcct tagatctcgc gaagaagaga gtacaccccg actacgtgat      900

caccacacaa cactggctgg gcctgcttgg gcccaatgga acccagccgc agtttgccaa      960

ctgcagtgtt tatgattttt ttgtgtggct ccattattat tctgttagag atacattatt     1020

aggaccagga cgcccctaca gggccataga tttctcacat caaggacctg catttgttac     1080

ctggcaccgg taccatttgt tgtgtctgga aagagatctc cagcgactca ttggcaatga     1140

gtcttttgct ttgccctact ggaactttgc cactgggagg aacgagtgtg atgtgtgtac     1200

agaccagctg tttggggcag cgagaccaga cgatccgact ctgattagtc ggaactcaag     1260

attctccagc tgggaaactg tctgtgatag cttggatgac tacaaccacc tggtcacctt     1320

gtgcaatgga acctatgaag gtttgctgag aagaaatcaa atgggaagaa acagcatgaa     1380

attgccaacc ttaaaagaca tacgagattg cctgtctctc cagaagtttg acaatcctcc     1440

cttcttccag aactctacct tcagtttcag gaatgctttg gaagggtttg ataaagcaga     1500

tgggactctg gattctcaag tgatgagcct tcataatttg gttcattcct tcctgaacgg     1560

gacaaacgct ttgccacatt cagccgccaa tgatcccatt tttgtggtga tttctaatcg     1620

tttgctttac aatgctacaa caaacatcct tgaacatgta agaaaagaga aagcgaccaa     1680

ggaactccct tccctgcatg tgctggttct tcattccttt actgatgcca tctttgatga     1740

gtggatgaaa agatttaatc ctcctgcaga tgcctggcct caggagctgg cccctattgg     1800

tcacaatcgg atgtacaaca tggttccttt cttccctcca gtgactaatg aagaactctt     1860

tttaacctca gaccaacttg gctacagcta tgccatcgat ctgccagttt cagttgaaga     1920

aactccaggt tggcccacaa ctctcttagt agtcatggga acactggtgg ctttggttgg     1980

tctttttgtg ctgttggctt ttcttcaata tagaagactt cgaaaaggat atacacccct     2040

aatggagaca catttaagca gcaagagata cacagaagaa gcctagggtg ctcatgcctt     2100

acctaagaga agaggctggc caagccacag ttctgacgct gacaataaag gaactaatcc     2160

tcactgttcc ttcttgagtt gaagatcttt gacataggtt cttctatagt gatgatgatc     2220

tcattcagaa gatgcttagc tgtagtttcc gctttgcttg cttgtttaac aaacccaact     2280

aaagtgcttg aggctacctc taccttcaaa taaagataga cctgacaatt tgtgatatct     2340

aataataacc ccccccccaa tattgattaa gcctcctcct tttctgaaag catttaaaaa     2400

aaa                                                                   2403


<210>  1757
<211>  7852
<212>  DNA
<213>  homo sapiens

<400>  1757
ggcgctgagc gagctcggag cccgcgctgt gcgcctgcgg ccggggcgcc ccgccgagcg       60

ccggtgcccc ggctcccggg ccgccttcgc cgcgcgggaa ggattcttca aaattaacag      120

aaaccaattc gggccagctg aagagaaaaa ataaaggtgg ctcccggctg cctctgctgc      180

agttcagagc aacttcagga gcttcccagc cgagagcttc aggacgcctt tcctgtccca      240

ctggcccagt tgccacaaca aacaacagag aagacggtga ccatggggga tgtgaagctg      300

gttgcctcgt cacacatttc caaaacctcc ctcagtgtgg atccctcaag agttgactcc      360

atgcccctga cagaggcccc tgctttcatt ttgccccctc ggaacctctg catcaaagaa      420

ggagccaccg ccaagttcga agggcgggtc cggggttacc cagagcccca ggtgacatgg      480

cacagaaacg ggcaacccat caccagcggg ggccgcttcc tgctggattg cggcatccgg      540

gggactttca gccttgtgat tcatgctgtc catgaggagg acaggggaaa gtatacctgt      600

gaagccacca atggcagtgg tgctcgccag gtgacagtgg agttgacagt agaaggaagt      660

tttgcgaagc agcttggtca gcctgttgtt tccaaaacct taggggatag attttcagct      720

ccagcagtgg agacccgtcc tagcatctgg ggggagtgcc caccaaagtt tgctaccaag      780

ctgggccgag ttgtggtcaa agaaggacag atgggacgat tctcctgcaa gatcactggc      840

cggccccaac cgcaggtcac ctggctcaag ggaaatgttc cactgcagcc gagtgcccgt      900

gtgtctgtgt ctgagaagaa cggcatgcag gttctggaaa tccatggagt caaccaagat      960

gacgtgggag tgtacacgtg cctggtggtg aacgggtcgg ggaaggcctc gatgtcagct     1020

gaactttcca tccaaggttt ggacagtgcc aataggtcat ttgtgagaga aacaaaagcc     1080

accaattcag atgtcaggaa agaggtgacc aatgtaatct caaaggagtc gaagctggac     1140

agtctggagg ctgcagccaa aagcaagaac tgctccagcc cccagagagg tggctcccca     1200

ccctgggctg caaacagcca gcctcagccc ccaagggagt ccaagctgga gtcatgcaag     1260

gactcgccca gaacggcccc gcagaccccg gtccttcaga agacttccag ctccatcacc     1320

ctgcaggccg caagagttca gccggaacca agagcaccag gcctgggggt cctatcacct     1380

tctggagaag agaggaagag gccagctcct ccccgtccag ccaccttccc caccaggcag     1440

cctggcctgg ggagccaaga tgttgtgagc aaggctgcta acaggagaat ccccatggag     1500

ggccagaggg attcagcatt ccccaaattt gagagcaagc cccaaagcca ggaggtcaag     1560

gaaaatcaaa ctgtcaagtt cagatgtgaa gtttccggga ttccaaagcc tgaagtggcc     1620

tggttcctgg aaggcacccc cgtgaggaga caggaaggca gcattgaggt ttatgaagat     1680

gctggctccc attacctctg cctgctgaaa gcccggacca gggacagtgg gacatacagc     1740

tgcactgctt ccaacgccca aggccagctg tcctgtagct ggaccctcca agtggaaagg     1800

cttgccgtga tggaggtggc cccctccttc tccagtgtcc tgaaggactg cgctgttatt     1860

gagggccagg attttgtgct gcagtgctcc gtacggggga ccccagtgcc ccggatcact     1920

tggctgctga atgggcagcc catccagtac gctcgctcca cctgcgaggc cggcgtggct     1980

gagctccaca tccaggatgc cctgccggag gaccatggca cctacacctg cctagctgag     2040

aatgccttgg ggcaggtgtc ctgcagcgcc tgggtcaccg tccatgaaaa gaagagtagc     2100

aggaagagtg agtaccttct gcctgtggct cccagcaagc ccactgcacc catcttcctg     2160

cagggcctct ctgatctcaa agtcatggat ggaagccagg tcactatgac tgtccaagtg     2220

tcagggaatc caccccctga agtcatctgg ctgcacaatg ggaatgagat ccaagagtca     2280

gaggacttcc actttgaaca gagaggaact cagcacagcc tttgtatcca ggaagtgttc     2340

ccggaggaca cgggcacgta cacctgcgag gcctggaaca gcgctggaga ggtccgcacc     2400

caggccgtgc tcacggtaca agagcctcac gatggcaccc agccctggtt catcagtaag     2460

cctcgctcag tgacagcctc cctgggccag agtgtcctca tctcctgcgc catagctggt     2520

gacccctttc ctaccgtgca ctggctcaga gatggcaaag ccctctgcaa agacactggc     2580

cacttcgagg tgcttcagaa tgaggacgtg ttcaccctgg ttctaaagaa ggtgcagccc     2640

tggcatgccg gccagtatga gatcctgctc aagaaccggg ttggcgaatg cagttgccag     2700

gtgtcactga tgctacagaa cagctctgcc agagcccttc cacgggggag ggagcctgcc     2760

agctgcgagg acctctgtgg tggaggagtt ggtgctgatg gtggtggtag tgaccgctat     2820

gggtccctga ggcctggctg gccagcaaga gggcagggtt ggctagagga ggaagacggc     2880

gaggacgtgc gaggggtgct gaagaggcgc gtggagacga ggcagcacac tgaggaggcg     2940

atccgccagc aggaggtgga gcagctggac ttccgagacc tcctggggaa gaaggtgagt     3000

acaaagaccc tatcggaaga cgacctgaag gagatcccag ccgagcagat ggatttccgt     3060

gccaacctgc agcggcaagt gaagccaaag actgtgtctg aggaagagag gaaggtgcac     3120

agcccccagc aggtcgattt tcgctctgtc ctggccaaga aggggacttc caagaccccc     3180

gtgcctgaga aggtgccacc gccaaaacct gccaccccgg attttcgctc agtgctgggt     3240

ggcaagaaga aattaccagc agagaatggc agcagcagtg ccgagaccct gaatgccaag     3300

gcagtggaga gttccaagcc cctgagcaat gcacagcctt cagggccctt gaaacccgtg     3360

ggcaacgcca agcctgctga gaccctgaag ccaatgggca acgccaagcc tgccgagacc     3420

ctgaagccca tgggcaatgc caagcctgat gagaacctga aatccgctag caaagaagaa     3480

ctcaagaaag acgttaagaa tgatgtgaac tgcaagagag gccatgcagg gaccacagat     3540

aatgaaaaga gatcagagag ccaggggaca gccccagcct tcaagcagaa gctgcaagat     3600

gttcatgtgg cagagggcaa gaagctgctg ctccagtgcc aggtgtcttc tgacccccca     3660

gccaccatca tctggacgct gaacggaaag accctcaaga ccaccaagtt catcatcctc     3720

tcccaggaag gctcactctg ctccgtctcc atcgagaagg cactgcctga ggacagaggc     3780

ttatacaagt gtgtagccaa gaatgacgct ggccaggcgg agtgctcctg ccaagtcacc     3840

gtggatgatg ctccagccag tgagaacacc aaggccccag agatgaaatc ccggaggccc     3900

aagagctctc ttcctcccgt gctaggaact gagagtgatg cgactgtgaa aaagaaacct     3960

gcccccaaga cacctccgaa ggcagcaatg ccccctcaga tcatccagtt ccctgaggac     4020

cagaaggtac gcgcaggaga gtcagtggag ctgtttggca aagtgacagg cactcagccc     4080

atcacctgta cctggatgaa gttccgaaag cagatccagg aaagcgagca catgaaggtg     4140

gagaacagcg agaatggcag caagctcacc atcctggccg cgcgccagga gcactgcggc     4200

tgctacacac tgctggtgga gaacaagctg ggcagcaggc aggcccaggt caacctcact     4260

gtcgtggata agccagaccc cccagctggc acaccttgtg cctctgacat tcggagctcc     4320

tcactgaccc tgtcctggta tggctcctca tatgatgggg gcagtgctgt acagtcctac     4380

agcatcgaga tctgggactc agccaacaag acgtggaagg aactagccac atgccgcagc     4440

acctctttca acgtccagga cctgctgcct gaccacgaat ataagttccg tgtacgtgca     4500

atcaacgtgt atggaaccag tgagccaagc caggagtctg aactcacaac ggtaggagag     4560

aaacctgaag agccgaagga tgaagtggag gtgtcagatg atgatgagaa ggagcccgag     4620

gttgattacc ggacagtgac aatcaatact gaacaaaaag tatctgactt ctacgacatt     4680

gaggagagat taggatctgg gaaatttgga caggtctttc gacttgtaga aaagaaaact     4740

cgaaaagtct gggcagggaa gttcttcaag gcatattcag caaaagagaa agagaatatc     4800

cggcaggaga ttagcatcat gaactgcctc caccacccta agctggtcca gtgtgtggat     4860

gcctttgaag aaaaggccaa catcgtcatg gtcctggaga tcgtgtcagg aggggagctg     4920

tttgagcgca tcattgacga ggactttgag ctgacggagc gtgagtgcat caagtacatg     4980

cggcagatct cggagggagt ggagtacatc cacaagcagg gcatcgtgca cctggacctc     5040

aagccggaga acatcatgtg tgtcaacaag acgggcacca ggatcaagct catcgacttt     5100

ggtctggcca ggaggctgga gaatgcgggg tctctgaagg tcctctttgg caccccagaa     5160

tttgtggctc ctgaagtgat caactatgag cccatcggct acgccacaga catgtggagc     5220

atcggggtca tctgctacat cctagtcagt ggcctttccc ccttcatggg agacaacgat     5280

aacgaaacct tggccaacgt tacctcagcc acctgggact tcgacgacga ggcattcgat     5340

gagatctccg acgatgccaa ggatttcatc agcaatctgc tgaagaaaga tatgaaaaac     5400

cgcctggact gcacgcagtg ccttcagcat ccatggctaa tgaaagatac caagaacatg     5460

gaggccaaga aactctccaa ggaccggatg aagaagtaca tggcaagaag gaaatggcag     5520

aaaacgggca atgctgtgag agccattgga agactgtcct ctatggcaat gatctcaggg     5580

ctcagtggca ggaaatcctc aacagggtca ccaaccagcc cgctcaatgc agaaaaacta     5640

gaatctgaag aagatgtgtc ccaagctttc cttgaggctg ttgctgagga aaagcctcat     5700

gtaaaaccct atttctctaa gaccattcgc gatttagaag ttgtggaggg aagtgctgct     5760

agatttgact gcaagattga aggataccca gaccccgagg ttgtctggtt caaagatgac     5820

cagtcaatca gggagtcccg ccacttccag atagactacg atgaggacgg gaactgctct     5880

ttaattatta gtgatgtttg cggggatgac gatgccaagt acacctgcaa ggctgtcaac     5940

agtcttggag aagccacctg cacagcagag ctcattgtgg aaacgatgga ggaaggtgaa     6000

ggggaagggg aagaggaaga agagtgaaac aaagccagag aaaagcagtt tctaagtcat     6060

attaaaagga ctatttctct aaaactcaaa aaaaaaaaaa aaactcaaga tagtaaaagc     6120

acctagtgtg atagattatc ggttaggtca tttgtgggtt gattcttcag aaacagcagt     6180

tgatacctag cagcgttatt gatgggcatt aatctatgtt agttggcacc ttaagatact     6240

agtgcagcta gatttcattt agggaaatca ccagtaactt gactgaccaa ttgattttag     6300

agagaaagta accaaaccaa atatttatct gggcaaagtc ataaattctc cacttgaatg     6360

cgctcatgaa aaataaggcc aaaacaagag ttctgggcca cagctcagcc cagagggttc     6420

ctggggatgg gaggcctctc tctccccacc ccctgactct agagaactgg gttttctccc     6480

agtactccag caattcattt ctgaaagcag ttgagccact ttattccaaa gtacactgca     6540

gatgttcaaa ctctccattt ctctttcccc ttccacctgc cagttttgct gactctcaac     6600

ttgtcatgag tgtaagcatt aaggacatta tgcttcttcg attctgaaga caggtccctg     6660

ctcatggatg actctggctt ccttaggaaa atatttttct tccaaaatca gtaggaaatc     6720

taaacttatc ccctctttgc agatgtctag cagcttcaga catttggtta agaacccatg     6780

ggaaaaaaaa aatccttgct aatgtggttt cctttgtaaa ccaggattct tatttgtgct     6840

gttatagaat atcagctctg aacgtgtggt aaagattttt gtgtttgaat ataggagaaa     6900

tcagtttgct gaaaagttag tcttaattat ctattggcca cgatgaaaca gatttcaact     6960

gataaagagc tggagaactc catgtacttt ggaatctcct ccaagatagc cagagtttaa     7020

tacatcttca ttctcaacac tctccaaaga acttgaccta ccttatgggt tccatatttt     7080

tcttcttaaa tgtgcatcaa tcatgccttg cccccaacct ttaaatatat tcttagacct     7140

ggtaaatgca ctcagacttg cgtctttagg aatttttaac tttctttcac tacattggca     7200

cttaaatttt ttctttataa agctttttga aggtcataaa caaagaccat aattgatgat     7260

agacctaata catttcctct gtgtgtgtgt gtaacattcc aaatactttt tttttctttt     7320

ccactgtttg taaggtgcaa caatttaata tttttaaggg actttttaag agttccttaa     7380

gaaccaattt aaaattactt cagtgcaatc ctacacagta tcaacattag aattttgata     7440

ttagtcttat gttatcttcc attctatttt tatctgcttt ttgctgctag tttcaaactg     7500

ccagtatttt tccttttgct tttaaaatag ttacaatatt tttcatgata gccacagtat     7560

tgccacagtt tattataata aagggttttt atttgattta gcgcattcaa agcttttttc     7620

tatcactttt gtgttcagaa tataaccttt gtgtgcgtgt atgttgtgtg tgtgcatgtg     7680

tggcgtatat gtgtgttaca ggttaatgcc ttcttggaat tgtgttaatg ttctcttggt     7740

ttattatgcc atcagaatgg taaatgagaa cactacaact gtagtcagct cacaattttt     7800

aaataaagga taccacagtg catgctgttt gttcaaaaaa aaaaaaaaaa aa             7852


<210>  1758
<211>  7699
<212>  DNA
<213>  homo sapiens

<400>  1758
ggcgctgagc gagctcggag cccgcgctgt gcgcctgcgg ccggggcgcc ccgccgagcg       60

ccggtgcccc ggctcccggg ccgccttcgc cgcgcgggaa ggattcttca aaattaacag      120

aaaccaattc gggccagctg aagagaaaaa ataaaggtgg ctcccggctg cctctgctgc      180

agttcagagc aacttcagga gcttcccagc cgagagcttc aggacgcctt tcctgtccca      240

ctggcccagt tgccacaaca aacaacagag aagacggtga ccatggggga tgtgaagctg      300

gttgcctcgt cacacatttc caaaacctcc ctcagtgtgg atccctcaag agttgactcc      360

atgcccctga cagaggcccc tgctttcatt ttgccccctc ggaacctctg catcaaagaa      420

ggagccaccg ccaagttcga agggcgggtc cggggttacc cagagcccca ggtgacatgg      480

cacagaaacg ggcaacccat caccagcggg ggccgcttcc tgctggattg cggcatccgg      540

gggactttca gccttgtgat tcatgctgtc catgaggagg acaggggaaa gtatacctgt      600

gaagccacca atggcagtgg tgctcgccag gtgacagtgg agttgacagt agaaggaagt      660

tttgcgaagc agcttggtca gcctgttgtt tccaaaacct taggggatag attttcagct      720

ccagcagtgg agacccgtcc tagcatctgg ggggagtgcc caccaaagtt tgctaccaag      780

ctgggccgag ttgtggtcaa agaaggacag atgggacgat tctcctgcaa gatcactggc      840

cggccccaac cgcaggtcac ctggctcaag ggaaatgttc cactgcagcc gagtgcccgt      900

gtgtctgtgt ctgagaagaa cggcatgcag gttctggaaa tccatggagt caaccaagat      960

gacgtgggag tgtacacgtg cctggtggtg aacgggtcgg ggaaggcctc gatgtcagct     1020

gaactttcca tccaaggttt ggacagtgcc aataggtcat ttgtgagaga aacaaaagcc     1080

accaattcag atgtcaggaa agaggtgacc aatgtaatct caaaggagtc gaagctggac     1140

agtctggagg ctgcagccaa aagcaagaac tgctccagcc cccagagagg tggctcccca     1200

ccctgggctg caaacagcca gcctcagccc ccaagggagt ccaagctgga gtcatgcaag     1260

gactcgccca gaacggcccc gcagaccccg gtccttcaga agacttccag ctccatcacc     1320

ctgcaggccg caagagttca gccggaacca agagcaccag gcctgggggt cctatcacct     1380

tctggagaag agaggaagag gccagctcct ccccgtccag ccaccttccc caccaggcag     1440

cctggcctgg ggagccaaga tgttgtgagc aaggctgcta acaggagaat ccccatggag     1500

ggccagaggg attcagcatt ccccaaattt gagagcaagc cccaaagcca ggaggtcaag     1560

gaaaatcaaa ctgtcaagtt cagatgtgaa gtttccggga ttccaaagcc tgaagtggcc     1620

tggttcctgg aaggcacccc cgtgaggaga caggaaggca gcattgaggt ttatgaagat     1680

gctggctccc attacctctg cctgctgaaa gcccggacca gggacagtgg gacatacagc     1740

tgcactgctt ccaacgccca aggccagctg tcctgtagct ggaccctcca agtggaaagg     1800

cttgccgtga tggaggtggc cccctccttc tccagtgtcc tgaaggactg cgctgttatt     1860

gagggccagg attttgtgct gcagtgctcc gtacggggga ccccagtgcc ccggatcact     1920

tggctgctga atgggcagcc catccagtac gctcgctcca cctgcgaggc cggcgtggct     1980

gagctccaca tccaggatgc cctgccggag gaccatggca cctacacctg cctagctgag     2040

aatgccttgg ggcaggtgtc ctgcagcgcc tgggtcaccg tccatgaaaa gaagagtagc     2100

aggaagagtg agtaccttct gcctgtggct cccagcaagc ccactgcacc catcttcctg     2160

cagggcctct ctgatctcaa agtcatggat ggaagccagg tcactatgac tgtccaagtg     2220

tcagggaatc caccccctga agtcatctgg ctgcacaatg ggaatgagat ccaagagtca     2280

gaggacttcc actttgaaca gagaggaact cagcacagcc tttgtatcca ggaagtgttc     2340

ccggaggaca cgggcacgta cacctgcgag gcctggaaca gcgctggaga ggtccgcacc     2400

caggccgtgc tcacggtaca agagcctcac gatggcaccc agccctggtt catcagtaag     2460

cctcgctcag tgacagcctc cctgggccag agtgtcctca tctcctgcgc catagctggt     2520

gacccctttc ctaccgtgca ctggctcaga gatggcaaag ccctctgcaa agacactggc     2580

cacttcgagg tgcttcagaa tgaggacgtg ttcaccctgg ttctaaagaa ggtgcagccc     2640

tggcatgccg gccagtatga gatcctgctc aagaaccggg ttggcgaatg cagttgccag     2700

gtgtcactga tgctacagaa cagctctgcc agagcccttc cacgggggag ggagcctgcc     2760

agctgcgagg acctctgtgg tggaggagtt ggtgctgatg gtggtggtag tgaccgctat     2820

gggtccctga ggcctggctg gccagcaaga gggcagggtt ggctagagga ggaagacggc     2880

gaggacgtgc gaggggtgct gaagaggcgc gtggagacga ggcagcacac tgaggaggcg     2940

atccgccagc aggaggtgga gcagctggac ttccgagacc tcctggggaa gaaggtgagt     3000

acaaagaccc tatcggaaga cgacctgaag gagatcccag ccgagcagat ggatttccgt     3060

gccaacctgc agcggcaagt gaagccaaag actgtgtctg aggaagagag gaaggtgcac     3120

agcccccagc aggtcgattt tcgctctgtc ctggccaaga aggggacttc caagaccccc     3180

gtgcctgaga aggtgccacc gccaaaacct gccaccccgg attttcgctc agtgctgggt     3240

ggcaagaaga aattaccagc agagaatggc agcagcagtg ccgagaccct gaatgccaag     3300

gcagtggaga gttccaagcc cctgagcaat gcacagcctt cagggccctt gaaacccgtg     3360

ggcaacgcca agcctgctga gaccctgaag ccaatgggca acgccaagcc tgccgagacc     3420

ctgaagccca tgggcaatgc caagcctgat gagaacctga aatccgctag caaagaagaa     3480

ctcaagaaag acgttaagaa tgatgtgaac tgcaagagag gccatgcagg gaccacagat     3540

aatgaaaaga gatcagagag ccaggggaca gccccagcct tcaagcagaa gctgcaagat     3600

gttcatgtgg cagagggcaa gaagctgctg ctccagtgcc aggtgtcttc tgacccccca     3660

gccaccatca tctggacgct gaacggaaag accctcaaga ccaccaagtt catcatcctc     3720

tcccaggaag gctcactctg ctccgtctcc atcgagaagg cactgcctga ggacagaggc     3780

ttatacaagt gtgtagccaa gaatgacgct ggccaggcgg agtgctcctg ccaagtcacc     3840

gtggatgatg ctccagccag tgagaacacc aaggccccag agatgaaatc ccggaggccc     3900

aagagctctc ttcctcccgt gctaggaact gagagtgatg cgactgtgaa aaagaaacct     3960

gcccccaaga cacctccgaa ggcagcaatg ccccctcaga tcatccagtt ccctgaggac     4020

cagaaggtac gcgcaggaga gtcagtggag ctgtttggca aagtgacagg cactcagccc     4080

atcacctgta cctggatgaa gttccgaaag cagatccagg aaagcgagca catgaaggtg     4140

gagaacagcg agaatggcag caagctcacc atcctggccg cgcgccagga gcactgcggc     4200

tgctacacac tgctggtgga gaacaagctg ggcagcaggc aggcccaggt caacctcact     4260

gtcgtggata agccagaccc cccagctggc acaccttgtg cctctgacat tcggagctcc     4320

tcactgaccc tgtcctggta tggctcctca tatgatgggg gcagtgctgt acagtcctac     4380

agcatcgaga tctgggactc agccaacaag acgtggaagg aactagccac atgccgcagc     4440

acctctttca acgtccagga cctgctgcct gaccacgaat ataagttccg tgtacgtgca     4500

atcaacgtgt atggaaccag tgagccaagc caggagtctg aactcacaac ggtaggagag     4560

aaacctgaag agccgaagga tgaagtggag gtgtcagatg atgatgagaa ggagcccgag     4620

gttgattacc ggacagtgac aatcaatact gaacaaaaag tatctgactt ctacgacatt     4680

gaggagagat taggatctgg gaaatttgga caggtctttc gacttgtaga aaagaaaact     4740

cgaaaagtct gggcagggaa gttcttcaag gcatattcag caaaagagaa agagaatatc     4800

cggcaggaga ttagcatcat gaactgcctc caccacccta agctggtcca gtgtgtggat     4860

gcctttgaag aaaaggccaa catcgtcatg gtcctggaga tcgtgtcagg aggggagctg     4920

tttgagcgca tcattgacga ggactttgag ctgacggagc gtgagtgcat caagtacatg     4980

cggcagatct cggagggagt ggagtacatc cacaagcagg gcatcgtgca cctggacctc     5040

aagccggaga acatcatgtg tgtcaacaag acgggcacca ggatcaagct catcgacttt     5100

ggtctggcca ggaggctgga gaatgcgggg tctctgaagg tcctctttgg caccccagaa     5160

tttgtggctc ctgaagtgat caactatgag cccatcggct acgccacaga catgtggagc     5220

atcggggtca tctgctacat cctaaaccgc ctggactgca cgcagtgcct tcagcatcca     5280

tggctaatga aagataccaa gaacatggag gccaagaaac tctccaagga ccggatgaag     5340

aagtacatgg caagaaggaa atggcagaaa acgggcaatg ctgtgagagc cattggaaga     5400

ctgtcctcta tggcaatgat ctcagggctc agtggcagga aatcctcaac agggtcacca     5460

accagcccgc tcaatgcaga aaaactagaa tctgaagaag atgtgtccca agctttcctt     5520

gaggctgttg ctgaggaaaa gcctcatgta aaaccctatt tctctaagac cattcgcgat     5580

ttagaagttg tggagggaag tgctgctaga tttgactgca agattgaagg atacccagac     5640

cccgaggttg tctggttcaa agatgaccag tcaatcaggg agtcccgcca cttccagata     5700

gactacgatg aggacgggaa ctgctcttta attattagtg atgtttgcgg ggatgacgat     5760

gccaagtaca cctgcaaggc tgtcaacagt cttggagaag ccacctgcac agcagagctc     5820

attgtggaaa cgatggagga aggtgaaggg gaaggggaag aggaagaaga gtgaaacaaa     5880

gccagagaaa agcagtttct aagtcatatt aaaaggacta tttctctaaa actcaaaaaa     5940

aaaaaaaaaa ctcaagatag taaaagcacc tagtgtgata gattatcggt taggtcattt     6000

gtgggttgat tcttcagaaa cagcagttga tacctagcag cgttattgat gggcattaat     6060

ctatgttagt tggcacctta agatactagt gcagctagat ttcatttagg gaaatcacca     6120

gtaacttgac tgaccaattg attttagaga gaaagtaacc aaaccaaata tttatctggg     6180

caaagtcata aattctccac ttgaatgcgc tcatgaaaaa taaggccaaa acaagagttc     6240

tgggccacag ctcagcccag agggttcctg gggatgggag gcctctctct ccccaccccc     6300

tgactctaga gaactgggtt ttctcccagt actccagcaa ttcatttctg aaagcagttg     6360

agccacttta ttccaaagta cactgcagat gttcaaactc tccatttctc tttccccttc     6420

cacctgccag ttttgctgac tctcaacttg tcatgagtgt aagcattaag gacattatgc     6480

ttcttcgatt ctgaagacag gtccctgctc atggatgact ctggcttcct taggaaaata     6540

tttttcttcc aaaatcagta ggaaatctaa acttatcccc tctttgcaga tgtctagcag     6600

cttcagacat ttggttaaga acccatggga aaaaaaaaat ccttgctaat gtggtttcct     6660

ttgtaaacca ggattcttat ttgtgctgtt atagaatatc agctctgaac gtgtggtaaa     6720

gatttttgtg tttgaatata ggagaaatca gtttgctgaa aagttagtct taattatcta     6780

ttggccacga tgaaacagat ttcaactgat aaagagctgg agaactccat gtactttgga     6840

atctcctcca agatagccag agtttaatac atcttcattc tcaacactct ccaaagaact     6900

tgacctacct tatgggttcc atatttttct tcttaaatgt gcatcaatca tgccttgccc     6960

ccaaccttta aatatattct tagacctggt aaatgcactc agacttgcgt ctttaggaat     7020

ttttaacttt ctttcactac attggcactt aaattttttc tttataaagc tttttgaagg     7080

tcataaacaa agaccataat tgatgataga cctaatacat ttcctctgtg tgtgtgtgta     7140

acattccaaa tacttttttt ttcttttcca ctgtttgtaa ggtgcaacaa tttaatattt     7200

ttaagggact ttttaagagt tccttaagaa ccaatttaaa attacttcag tgcaatccta     7260

cacagtatca acattagaat tttgatatta gtcttatgtt atcttccatt ctatttttat     7320

ctgctttttg ctgctagttt caaactgcca gtatttttcc ttttgctttt aaaatagtta     7380

caatattttt catgatagcc acagtattgc cacagtttat tataataaag ggtttttatt     7440

tgatttagcg cattcaaagc ttttttctat cacttttgtg ttcagaatat aacctttgtg     7500

tgcgtgtatg ttgtgtgtgt gcatgtgtgg cgtatatgtg tgttacaggt taatgccttc     7560

ttggaattgt gttaatgttc tcttggttta ttatgccatc agaatggtaa atgagaacac     7620

tacaactgta gtcagctcac aatttttaaa taaaggatac cacagtgcat gctgtttgtt     7680

caaaaaaaaa aaaaaaaaa                                                  7699


<210>  1759
<211>  2744
<212>  DNA
<213>  homo sapiens

<400>  1759
ccgcggaccc accccctcgc ttccggcatc ggctgtgggg agtaccggct gcagtcggct       60

gtgccgggag ggtaggatgg cgtctggccg atgcggtgat agcaccgaaa gcagacggcc      120

gccaggcgct ccccctaccc cccgaagttt ctccccagcg gcgggggatg ggggtaggcg      180

gttcctctgt tctttctgcg ttccccgcgg cctcttacca cagagacgcg ggcctccacc      240

gtcctagccc tcccgccctg ttctctagtg cggactagag cgtctcctcg ccatttcctg      300

tcgccctggg gccccgcggg gaaaaagggg gagtagcagg acagcggagg gaagtcgcga      360

gcttaggtgg tgtgtagacg ccggaagtgt tgggaaggag gccggaagct aggggcgggg      420

ccaggaagtg aggaggggcg ggggtttatg aggagtccaa gggagcattg gggcagactt      480

gtactcagag ccacctgagg gacttggcgg tggcgcccag cactgtcccc tcccctcgta      540

gagacacggt tgtcgtttgg gagtagggaa cactgtgttg gggtgggttg tcggcaggac      600

atctctctgg ctgctcttgg ggcgaggtgt ggaggggcag ggctgggggt ggagccgggt      660

cgccagggcg tcggtaggga agacccccgc ccctcgcccc cccaccgaac ctctacactg      720

gctggctgga cactaagatg gctgccgttg ccatgacacc caaccctgtg cagacccttc      780

aggaggaggc ggtgtgcgcc atctgcctcg attacttcac ggaccccgtg tccatcggct      840

gcgggcacaa cttctgccga gtttgtgtaa cccagttgtg gggtggggag gatgaggagg      900

acagagatga gttagatcgg gaggaggagg aggaggacgg agaggaggag gaagtggagg      960

ctgtgggggc tggcgcgggg tgggacaccc ccatgcggga tgaagactac gagggtgaca     1020

tggaggagga ggtcgaggag gaagaagagg gtgtgttctg gaccagtggc atgagcaggt     1080

ccagctggga caacatggac tatgtgtggg aggaggagga cgaggaggaa gacctggact     1140

actacttggg ggacatggag gaggaggacc tgagggggga ggatgaggag gacgaggagg     1200

aagtgctgga ggaggttgag gaagaggatc tagaccccgt caccccactg cccccgcctc     1260

cagcccctcg gaggtgcttc acatgccctc agtgccgaaa gagctttcct cggcggagct     1320

tccgccccaa cctgcagctg gccaatatgg tccaggtgat tcggcagatg cacccaaccc     1380

ctggtcgagg gagccgcgtg accgatcagg gcatctgtcc caaacaccaa gaagccctga     1440

agctcttctg cgaggtagac gaagaggcca tctgtgtggt gtgccgagaa tccaggagcc     1500

acaaacagca cagcgtggtg ccattggagg aggtggtgca ggagtacaag gccaaactgc     1560

aggggcacgt ggaaccactg aggaagcacc tggaggcagt gcagaagatg aaagccaagg     1620

aggagaggcg agtgacagaa ctgaagagcc agatgaagtc agagctggca gcggtggcct     1680

cggagtttgg gcgactgaca cggtttctgg ctgaagagca ggcagggctg gaacggcgtc     1740

tcagagagat gcatgaagcc cagctggggc gtgcgggagc cgcggctagt cgccttgcag     1800

aacaggccgc ccagctcagc cgcctgctgg cagaggccca ggagcggagc cagcaggggg     1860

gtctccggct gctccaggac atcaaggaga ctttcaatag gtgtgaagag gtacagctgc     1920

agcccccaga ggtctggtcc cctgacccgt gccaacccca tagccatgac ttcctgacag     1980

atgccatcgt gaggaaaatg agccggatgt tctgtcaggc tgcgagagtg gacctgacgc     2040

tggaccctga cacggctcac ccggccctga tgctgtcccc tgaccgccgg ggggtccgcc     2100

tggcagagcg gcggcaggag gttgctgacc atcccaagcg cttctcggcc gactgctgcg     2160

tactgggggc ccagggcttc cgctccggcc ggcactactg ggaggagcct aaagaaccct     2220

cctggcctcc agctcagcct tctctcacct actatgtctg tccaacagac cggccagaat     2280

ttagcttcac ttgagagaga tctggaatgg tcgccatgat tgaaaccacg caccattaca     2340

tcatcattac attaattaca tcaacataaa ttatttcttc ccccttccct tttccagcac     2400

tcaaccaagg agcaaagctc atcccacccc acacccctcc caggtctgct cactgccagg     2460

ctcctctccc ctttgttcag tggagctggc ttttctccca gcccctttcc atgcctttca     2520

ctccatttgg caagctctga gggggagcct ggggacgggt ttgggtcccc aggaggagag     2580

ccttgggtat aatctatttt tctaggagcc tcttgccttg tcacttgcag ctttcgccct     2640

ctgctttgat ggctgaggtg aactcatgtt ctttgggaaa agggaaggcg tgctgtggaa     2700

ataaaatgtt tatttgcttc tctaaaaaaa aaaaaaaaaa aaaa                      2744


<210>  1760
<211>  3138
<212>  DNA
<213>  homo sapiens

<400>  1760
gctctctcct cctcctcctc ctcttcctct ctggtctcct ccctcctccg ggctgggttg       60

caaatggctt cgttccccga gaccgatttc cagatctgct tgctgtgcaa ggagatgtgc      120

ggctcgccgg cgccgctctc ctccaactcg tccgcgtcgt cgtcctcctc gcagacgtcc      180

acgtcgtcgg ggggcggcgg cgggggccct ggggcggcgg cgcgccgcct acacgtcctg      240

ccctgcctgc acgccttctg ccgcccctgc ctcgaggcgc accggctgcc ggcggcgggc      300

ggcggcgcgg cgggagagcc gctcaagctg cgctgccccg tgtgcgacca gaaagtagtg      360

ctagccgagg cggcgggtat ggacgcgctg ccttcgtccg ccttcctgct tagcaacctg      420

ctcgacgcgg tggtggccac tgccgacgag ccgccgccca agaacgggcg cgccggcgct      480

ccggcgggag cgggcggcca cagcaaccac cggcaccacg ctcaccacgc gcacccgcgc      540

gcgtccgcct ccgcgccgcc actcccgcag gcgccgcagc cgcccgcgcc ttcccgctcg      600

gcacccggcg gccctgccgc ttccccgtcg gcgctgctgc tccgccgtcc tcacggctgc      660

agctcgtgcg atgagggcaa cgcagcttct tcgcgctgcc tcgactgcca ggagcacctg      720

tgcgacaact gcgtccgagc gcaccagcgc gtgcgcctca ccaaggacca ctacatcgag      780

cgcggcccgc cgggtcccgg tgccgcagca gcggcgcagc agctcgggct cgggccgccc      840

tttcccggcc cgcccttctc catcctctca gtgtttcccg agcgcctcgg cttctgccag      900

caccacgacg acgaggtgct gcacctgtac tgtgacactt gctctgtacc catctgtcgt      960

gagtgcacaa tgggccggca tgggggccac agcttcatct acctccagga ggcactgcag     1020

gactcacggg cactcaccat ccagctgctg gcagatgccc agcagggacg acaggcaatc     1080

cagctgagca tcgagcaggc ccagacggtg gcggaacagg tggagatgaa ggcgaaggtt     1140

gtgcagtcgg aggtcaaagc cgtgacggcg aggcataaga aagccctgga ggaacgcgag     1200

tgtgagctgc tgtggaaggt agaaaagatc cgccaggtga aagccaagtc tctgtacctg     1260

caggtggaga agctgcggca aaacctcaac aagcttgaga gcaccatcag tgccgtgcag     1320

caggtcctgg aggagggtag agcgctagac atcctactgg cccgagaccg gatgctggcc     1380

caggtgcagg agctgaagac cgtgcggagc ctcctgcagc cccaggaaga cgaccgagtc     1440

atgttcacac cccccgatca ggcactgtac cttgccatca agtcttttgg ctttgttagc     1500

agcggggcct ttgccccact caccaaggcc acaggcgatg gcctcaagcg tgccctccag     1560

ggtaaggtgg cctccttcac agtcattggt tatgaccacg atggtgagcc ccgcctctca     1620

ggaggcgacc tgatgtcggc tgtggtcctg ggccctgatg gcaacctgtt tggtgcagag     1680

gtgagtgatc agcagaatgg gacatacgtg gtgagttacc gaccccagct ggagggtgag     1740

cacctggtat ctgtgacact gtgcaaccag cacattgaga acagcccttt caaggtggtg     1800

gtcaagtcag gccgcagcta cgtgggcatt gggctcccgg gcctgagctt cggcagtgag     1860

ggtgacagcg atggcaagct ctgccgccct tggggtgtga gtgtagacaa ggagggctac     1920

atcattgtcg ccgaccgcag caacaaccgc atccaggtgt tcaagccctg cggcgccttc     1980

caccacaaat tcggcaccct gggctcccgg cctgggcagt tcgaccgacc agccggcgtg     2040

gcctgtgacg cctcacgcag gatcgtggtg gctgacaagg acaatcatcg catccagatc     2100

ttcacgttcg agggccagtt cctcctcaag tttggtgaga aaggaaccaa gaatgggcag     2160

ttcaactacc cttgggatgt ggcggtgaat tctgagggca agatcctggt ctcagacacg     2220

aggaaccacc ggatccagct gtttgggcct gatggtgtct tcctaaacaa gtatggcttc     2280

gagggggctc tctggaagca ctttgactcc ccacggggtg tggccttcaa ccatgagggc     2340

cacttggtgg tcactgactt caacaaccac cggctcctgg ttattcaccc cgactgccag     2400

tcggcacgct ttctgggctc ggagggcaca ggcaatgggc agttcctgcg cccacaaggg     2460

gtagctgtgg accaggaagg gcgcatcatt gtggcggatt ccaggaacca tcgggtacag     2520

atgtttgaat ccaacggcag cttcctgtgc aagtttggtg ctcaaggcag cggctttggg     2580

cagatggacc gcccttccgg catcgccatc acccccgacg gaatgatcgt tgtggtggac     2640

tttggcaaca atcgaatcct cgtcttctaa ttgcatttcc taggtttctg tgtttggggt     2700

gtgtgtgcgt gtctctctct ctctctctct ctttctcttt ctctctcttt ttgaatttca     2760

aagaagaaac agtctcaggg aaatttcttt tttctttttt ttttttaaag agaacaagaa     2820

aagtacaaca ttgcttaagt cctacctcat ctttattttt ttacagatga atgtacttat     2880

cttttctgca gggattgagc ctgtgaagtg ataatttcta tctacctcat aaatctttac     2940

atttccttct gcaacaggcc ctcttcccct cctcagtgga gtttgcattt ccctcttccc     3000

ctgcgtgggg catgatatgc acaagcctgg catctgtatg gctgggaggg cactggatgt     3060

gtgtggtggg gtgtattctg tagattgagc caaggaaaca caaaaaaaaa ctactaagta     3120

aaaaaacaaa aaactata                                                   3138


<210>  1761
<211>  942
<212>  DNA
<213>  homo sapiens

<400>  1761
ggcggcgtgt ttgaaagcga ggccaaagtg ggtgggagcg cgtgctgttg ggagttgctt       60

ggaggttggc ggcgcggggc tgaaggctag caaaccgagc gatcatgtcg cacaaacaaa      120

tttactattc ggacaaatac gacgacgagg agtttgagta tcggttagtg ctggcgcggg      180

agcaatagcg agggtcgtga gctttggccg ctgagggcac aaggaattag taacaggaac      240

tgaggcgata gaattggcgc atgcgtacga gacatgtcat gctgcccaag gacatagcca      300

agctggtccc taaaacccat ctgatgtctg aatctgaatg gaggaatctt ggcgttcagc      360

agagtcaggg atgggtccat tatatgatcc atgaaccaga acctcacatc ttgctgttcc      420

ggcgcccact acccaagaaa ccaaagaaat gaagctggca agctactttt cagcctcaag      480

ctttacacag ctgtccttac ttcctaacat ctttctgata acattattat gttgccttct      540

tgtttctcac tttgatattt aaaagatgtt caatacactg tttgaatgtg ctggtaactg      600

ctttgcttct tgagtagagc caccaccacc atagcccagc cagatgagtg ctctgtggac      660

ccacagccta agctgagtgt gaccccagaa gccacgatgt gctctgtatc cagaacacac      720

ttggcagatg gaggaagcat ctgagtttga gaccatggct gttacaggga tcatgtaaac      780

ttgctgtttt tgttttttcc tgccgggtgt tgtatgtgtg gtgacttgcg gatttatgtt      840

tcagtgtact ggaaactttc cattttattc aagaaatctg ttcatgttaa aagccttgat      900

taaagaggaa gtttttataa tctaaaaaaa aaaaaaaaaa aa                         942


<210>  1762
<211>  2971
<212>  DNA
<213>  homo sapiens

<400>  1762
aatggggaca tgatgggggg cggagccgag gcctccgaag cggaagtggg ttgctgttga       60

ggcggcggca tctttctcga ggagctctcc tgggcggctg aagaaggagc ttcttctccg      120

gagtgcgccg gcggtggcgc ctgcggacct aactagctcc aggttaggcc gagctttgcg      180

ggaaagcagc ggacttgaaa atactggaaa tctgtccgga tccaaattat tttgcaagcc      240

agatgagtaa ccagagggca tgaaaggttg agaacatttg acttccctgc aaaccttggt      300

atagatcact tccttttctg taggaaagga aaggcaccaa agagcacaat gagtacaaga      360

aagcgtcgtg gtggagcaat aaattctaga caagctcaga agcgaactcg ggaagcaacc      420

tccacccccg agatctcctt ggaagcagaa cccatagaac tcgtggaaac tgctggagat      480

gaaattgtgg acctcacttg tgaatcttta gagcctgtgg tggttgatct gactcacaat      540

gactctgttg tgattgttga cgaaagaaga agaccaagga ggaatgctag gaggctgccc      600

caggaccatg ctgacagctg tgtggtgagc agtgacgatg aggagttgtc cagggacaga      660

gacgtatatg tgactaccca tactcccaga aacgccaggg atgagggcgc tacaggcctc      720

aggccctcag gtactgtcag ttgtcccatc tgcatggacg gatactcaga gatcgtgcag      780

aatggacgtc tcatcgtttc cacagaatgc ggccatgtct tctgtagcca gtgcctccgt      840

gattccctga agaatgctaa tacttgccca acttgtagga aaaagatcaa ccacaaacgg      900

taccacccca tttatatatg aagtattcag agccccccag gagagacgga tggacagaca      960

gacagccagg ttctccagtg gtatctgcct ccattttcct gagatcaaaa agactgtttc     1020

gaaaccaaca tctgatatgt aaactgctct tttgtttcca accccttcct tttgttatct     1080

ccagtttgat gctatggcgc tggacccagg gccctcccag gccatctctg ttcctctggg     1140

gtggtccagt tctagagtgg gagaaaggga gtcaggcgca ttgggaatcg tggttccagt     1200

ctggttgcag aatctgcaca tttgccaaga aattttccct gtttggaaag tttgccccag     1260

ctttcccggg cacaccacct tttgtcccaa gtgtctgccg gtcgaccaat ctgcctgcca     1320

cacattgacc aagccagacc cggttcaccc agctcgagga tcccaggttg aagagtggcc     1380

ccttgaggcc ctggaaagac caatcactgg acttcttccc ttgagagtca gaggtcaccc     1440

gtgattctgc ctgcacctta tcattgatct gcagtgattt ctgcaaatca agagaaactc     1500

tgcagggcac tcccctgttt cctaagaacg aaaaagtgca ataaaggcca ttcgttacct     1560

acttttcagc agcccacaag atgtagcact attagtgtcc ccctcagagg cttaatgttg     1620

cctgtggagc agtgcccatc ccagcccgtt tctgcccacc agttgttctc aggaacctta     1680

cccatgctcc agcgtccttc acctggcaca ggacatgcaa gataaatagg gcaggcacgt     1740

gtttgggtgt cctctctttt ctgataaaat ccatcccgtg tttgccacac gccctccagt     1800

cctcagttcc cactgcctaa cgtctgcccc cgtgtagata ctgagaggtg gtggcagtaa     1860

ttgtggcctt atcagccgct cagttccagg cttttgccca ggtcactgtt gccccatgtt     1920

cggagaacct ggcccacctg tcttggcttt ctcatccttc ccaacccagt gccgtttatt     1980

tcagaagctt cctggccact gggcttggat gcttcgggct tctgactgct ccataggttt     2040

tgactggtga aacaggggcc cagatgacaa cctctccttc gctccacagg tacgcgggag     2100

cctcaggttc tctcaggggc agcaaagtgg cccaagctgc ccctgacagc acagggcctg     2160

gggggtggct aacgagagag gccttacagt gccggcatgc ctcctcttcc actgtcgtcc     2220

ttcctcagag ggcctcacgc caaacaaacg gccttttcgt gtgaaacatc ttcagggcgg     2280

gaaaggggcc acttctggct ttgttagcaa taactgacct tcagtttacc cttctgaagg     2340

agcagggact cagcacagaa ttcactttag acggggctga aggagtgtcc ctcctctatg     2400

tgaaaagaaa attgttttat tcttcattct gactttttaa ctgtttggct cacttccagt     2460

tagtttgaat gaaaataata attttctact tggagttgaa gagggcagaa tccgcagctc     2520

tcatcattgt gatgtgtagc atgtctgccc tctgactgga catcattgcc attaactttc     2580

ttctgggcat cacggcaatg tcacgatgcc cagacttgga gcaaggcaac cttggagtca     2640

gtccactcat aaaatatggt aacacccatt ttaaaattta agttttgtcc ttaaagacaa     2700

cttcagtggt taattataaa agttgtgtta cttcgtccta aattaaattg atagaaagat     2760

ttaaaaatgt gttttgtttc tactattcag aaactgcgaa ctagggaaag gttggtatga     2820

agaaatgtct ttcctttttt caatgtacat agttcaactc tttctttgtt acatttaaac     2880

tatatccatg gatatcagtc tgctttggac tcctctgcta gtgttacaga tggaaataaa     2940

accattaatt tgaaccaaat aaaaaaaaaa a                                    2971


<210>  1763
<211>  1300
<212>  DNA
<213>  homo sapiens

<400>  1763
aagccgcaga gagcgggctc tgtcccgccc gctccccagg tggacgtggt cttggcatcc       60

acgccaatga gaatgtgagg gcggggcctg aatagacgca ggaaatggcg acggccgcgg      120

gtctgtgagc agcgggggcg gggcctggtt gtggcccctc cttctcccgt ccccaagttc      180

cctgggtggg aacggggtct tggggtccct ggctgggtgg ccagaccccg aagccagcgc      240

tgggaagggc tgcggatgcc cgggtcagag gaaggggcag gtccaaggac acgcgggtct      300

ggtcctgggc aagaaccgcc ccctctccgg gcctgcttca gtcttccttt gcagaacaac      360

gggccaggcc ccttccctct gcccccgggt gcttgaagtc tagccccatc ctggtccaat      420

gcgctcttgg tagcctcctt tcccagctgc ccgcccgccg ccatgccgcc cttactgccc      480

ctgcgcctgt gccggctgtg gccccgcaac cctccctccc ggctcctcgg agcggccgcc      540

gggcagcggt ccagacccag tacttattat gaactgttgg gggtgcatcc tggtgccagc      600

actgaggaag ttaaacgagc tttcttctcc aagtccaaag agctgcaccc agaccgggac      660

cctgggaacc caagcctgca cagccgcttt gtggagctga gcgaggcata ccgtgtgctc      720

agccgtgagc agagccgccg cagctatgat gaccagctcc gctcaggtag tcccccaaag      780

tctccacgaa ccacagtcca tgacaagtct gcccaccaaa cacacagctc ctggacaccc      840

cccaacgcac agtactggtc ccagtttcac agcgtgaggc cacaggggcc ccagttgagg      900

cagcagcaac acaaacaaaa caaacaagtg ctggggtact gcctcctcct catgctggcg      960

ggcatgggcc tgcactacat tgccttcagg aaggtgaagc agatgcacct taacttcatg     1020

gatgaaaagg atcggatcat cacagccttc tacaacgaag cccgggcacg ggccagggcc     1080

aacagaggca tccttcagca ggagcgacaa cggctagggc agcggcagcc gccaccatcc     1140

gagccaaccc aaggccccga gatcgtgccc cggggcgccg gcccctgagg ggctcacctg     1200

gatggggcct gcagtgcgtt cccgctttgc ttccttccct ggacggcccg ctccccgaaa     1260

cgcgcgcaat aaagtgattc gcagaaaaaa aaaaaaaaaa                           1300


<210>  1764
<211>  3272
<212>  DNA
<213>  homo sapiens

<400>  1764
aaccgcggat cccgcagctg caggaggcgc ccggcccggc ggagcagccc tagccgccac       60

cgtcgctctc gcagctctcg tcgccactgc caccgccgcc gccgtcactg cgtcctggct      120

ccggctcccg cgccctcccg gccggccatg cagccccgcc gcgcccaggc gcccggtgcg      180

cagctgctgc ccgcgctggc cctgctgctg ctgctgctcg gagcggggcc ccgaggcagc      240

tccctggcca acccggtgcc cgccgcgccc ctgtctgcgc ccgggccgtg cgccgcgcag      300

ccctgccgga atgggggtgt gtgcacctcg cgccctgagc cggacccgca gcacccggcc      360

cccgccggcg agcctggcta cagctgcacc tgccccgccg ggatctccgg cgccaactgc      420

cagcttgttg cagatccttg tgccagcaac ccttgtcacc atggcaactg cagcagcagc      480

agcagcagca gcagcgatgg ctacctctgc atttgcaatg aaggctatga aggtcccaac      540

tgtgaacagg cacttcccag tctcccagcc actggctgga ccgaatccat ggcaccccga      600

cagcttcagc ctgttcctgc tactcaggag cctgacaaaa tcctgcctcg ctctcaggca      660

acggtgacac tgcctacctg gcagccgaaa acagggcaga aagttgtaga aatgaaatgg      720

gatcaagtgg aggtgatccc agatattgcc tgtgggaatg ccagttctaa cagctctgcg      780

ggtggccgcc tggtatcctt tgaagtgcca cagaacacct cagtcaagat tcggcaagat      840

gccactgcct cactgatttt gctctggaag gtcacggcca caggattcca acagtgctcc      900

ctcatagatg gacgaagtgt gacccccctt caggcttcag ggggactggt cctcctggag      960

gagatgctcg ccttggggaa taatcacttt attggttttg tgaatgattc tgtgactaag     1020

tctattgtgg ctttgcgctt aactctggtg gtgaaggtca gcacctgtgt gccgggggag     1080

agtcacgcaa atgacttgga gtgttcagga aaaggaaaat gcaccacgaa gccgtcagag     1140

gcaacttttt cctgtacctg tgaggagcag tacgtgggta ctttctgtga agaatacgat     1200

gcttgccaga ggaaaccttg ccaaaacaac gcgagctgta ttgatgcaaa tgaaaagcaa     1260

gatgggagca atttcacctg tgtttgcctt cctggttata ctggagagct ttgccagtcc     1320

aagattgatt actgcatcct agacccatgc agaaatggag caacatgcat ttccagtctc     1380

agtggattca cctgccagtg tccagaagga tacttcggat ctgcttgtga agaaaaggtg     1440

gacccctgcg cctcgtctcc gtgccagaac aacggcacct gctatgtgga cggggtacac     1500

tttacctgca actgcagccc gggcttcaca gggccgacct gtgcccagct tattgacttc     1560

tgtgccctca gcccctgtgc tcatggcacg tgccgcagcg tgggcaccag ctacaaatgc     1620

ctctgtgatc caggttacca tggcctctac tgtgaggagg aatataatga gtgcctctcc     1680

gctccatgcc tgaatgcagc cacctgcagg gacctcgtta atggctatga gtgtgtgtgc     1740

ctggcagaat acaaaggaac acactgtgaa ttgtacaagg atccctgcgc taacgtcagc     1800

tgtctgaacg gagccacctg tgacagcgac ggcctgaatg gcacgtgcat ctgtgcaccc     1860

gggtttacag gtgaagagtg cgacattgac ataaatgaat gtgacagtaa cccctgccac     1920

catggtggga gctgcctgga ccagcccaat ggttataact gccactgccc gcatggttgg     1980

gtgggagcaa actgtgagat ccacctccaa tggaagtccg ggcacatggc ggagagcctc     2040

accaacatgc cacggcactc cctctacatc atcattggag ccctctgcgt ggccttcatc     2100

cttatgctga tcatcctgat cgtggggatt tgccgcatca gccgcattga ataccagggt     2160

tcttccaggc cagcctatga ggagttctac aactgccgca gcatcgacag cgagttcagc     2220

aatgccattg catccatccg gcatgccagg tttggaaaga aatcccggcc tgcaatgtat     2280

gatgtgagcc ccatcgccta tgaagattac agtcctgatg acaaaccctt ggtcacactg     2340

attaaaacta aagatttgta atcttttttt ggattatttt tcaaaaagat gagatactac     2400

actcatttaa atatttttaa gaaaataaaa agcttaagaa atttaaaatg ctagctgctc     2460

aagagttttc agtagaatat ttaagaacta attttctgca gcttttagtt tggaaaaaat     2520

attttaaaaa caaaatttgt gaaacctata gacgatgttt taatgtacct tcagctctct     2580

aaactgtgtg cttctactag tgtgtgctct tttcactgta gacactatca cgagacccag     2640

attaatttct gtggttgtta cagaataagt ctaatcaagg agaagtttct gtttgacgtt     2700

tgagtgccgg ctttctgagt agagttagga aaaccacgta acgtagcata tgatgtataa     2760

tagagtatac ccgttactta aaaagaagtc tgaaatgttc gttttgtgga aaagaaacta     2820

gttaaattta ctattcctaa cccgaatgaa attagccttt gccttattct gtgcatgggt     2880

aagtaactta tttctgcact gttttgttga actttgtgga aacattcttt cgagtttgtt     2940

tttgtcattt tcgtaacagt cgtcgaacta ggcctcaaaa acatacgtaa cgaaaaggcc     3000

tagcgaggca aattctgatt gatttgaatc tatatttttc tttaaaaagt caagggttct     3060

atattgtgag taaattaaat ttacatttga gttgtttgtt gctaagaggt agtaaatgta     3120

agagagtact ggttccttca gtagtgagta tttctcatag tgcagcttta tttatctcca     3180

ggatgttttt gtggctgtat ttgattgata tgtgcttctt ctgattcttg ctaatttcca     3240

accatattga ataaatgtga tcaagtcaag ga                                   3272


<210>  1765
<211>  3272
<212>  DNA
<213>  homo sapiens

<400>  1765
aaccgcggat cccgcagctg caggaggcgc ccggcccggc ggagcagccc tagccgccac       60

cgtcgctctc gcagctctcg tcgccactgc caccgccgcc gccgtcactg cgtcctggct      120

ccggctcccg cgccctcccg gccggccatg cagccccgcc gcgcccaggc gcccggtgcg      180

cagctgctgc ccgcgctggc cctgctgctg ctgctgctcg gagcggggcc ccgaggcagc      240

tccctggcca acccggtgcc cgccgcgccc ctgtctgcgc ccgggccgtg cgccgcgcag      300

ccctgccgga atgggggtgt gtgcacctcg cgccctgagc cggacccgca gcacccggcc      360

cccgccggcg agcctggcta cagctgcacc tgccccgccg ggatctccgg cgccaactgc      420

cagcttgttg cagatccttg tgccagcaac ccttgtcacc atggcaactg cagcagcagc      480

agcagcagca gcagcgatgg ctacctctgc atttgcaatg aaggctatga aggtcccaac      540

tgtgaacagg cacttcccag tctcccagcc actggctgga ccgaatccat ggcaccccga      600

cagcttcagc ctgttcctgc tactcaggag cctgacaaaa tcctgcctcg ctctcaggca      660

acggtgacac tgcctacctg gcagccgaaa acagggcaga aagttgtaga aatgaaatgg      720

gatcaagtgg aggtgatccc agatattgcc tgtgggaatg ccagttctaa cagctctgcg      780

ggtggccgcc tggtatcctt tgaagtgcca cagaacacct cagtcaagat tcggcaagat      840

gccactgcct cactgatttt gctctggaag gtcacggcca caggattcca acagtgctcc      900

ctcatagatg gacgaagtgt gacccccctt caggcttcag ggggactggt cctcctggag      960

gagatgctcg ccttggggaa taatcacttt attggttttg tgaatgattc tgtgactaag     1020

tctattgtgg ctttgcgctt aactctggtg gtgaaggtca gcacctgtgt gccgggggag     1080

agtcacgcaa atgacttgga gtgttcagga aaaggaaaat gcaccacgaa gccgtcagag     1140

gcaacttttt cctgtacctg tgaggagcag tacgtgggta ctttctgtga agaatacgat     1200

gcttgccaga ggaaaccttg ccaaaacaac gcgagctgta ttgatgcaaa tgaaaagcaa     1260

gatgggagca atttcacctg tgtttgcctt cctggttata ctggagagct ttgccagtcc     1320

aagattgatt actgcatcct agacccatgc agaaatggag caacatgcat ttccagtctc     1380

agtggattca cctgccagtg tccagaagga tacttcggat ctgcttgtga agaaaaggtg     1440

gacccctgcg cctcgtctcc gtgccagaac aacggcacct gctatgtgga cggggtacac     1500

tttacctgca actgcagccc gggcttcaca gggccgacct gtgcccagct tattgacttc     1560

tgtgccctca gcccctgtgc tcatggcacg tgccgcagcg tgggcaccag ctacaaatgc     1620

ctctgtgatc caggttacca tggcctctac tgtgaggagg aatataatga gtgcctctcc     1680

gctccatgcc tgaatgcagc cacctgcagg gacctcgtta atggctatga gtgtgtgtgc     1740

ctggcagaat acaaaggaac acactgtgaa ttgtacaagg atccctgcgc taacgtcagc     1800

tgtctgaacg gagccacctg tgacagcgac ggcctgaatg gcacgtgcat ctgtgcaccc     1860

gggtttacag gtgaagagtg cgacattgac ataaatgaat gtgacagtaa cccctgccac     1920

catggtggga gctgcctgga ccagcccaat ggttataact gccactgccc gcatggttgg     1980

gtgggagcaa actgtgagat ccacctccaa tggaagtccg ggcacatggc ggagagcctc     2040

accaacatgc cacggcactc cctctacatc atcattggag ccctctgcgt ggccttcatc     2100

cttatgctga tcatcctgat cgtggggatt tgccgcatca gccgcattga ataccagggt     2160

tcttccaggc cagcctatga ggagttctac aactgccgca gcatcgacag cgagttcagc     2220

aatgccattg catccatccg gcatgccagg tttggaaaga aatcccggcc tgcaatgtat     2280

gatgtgagcc ccatcgccta tgaagattac agtcctgatg acaaaccctt ggtcacactg     2340

attaaaacta aagatttgta atcttttttt ggattatttt tcaaaaagat gagatactac     2400

actcatttaa atatttttaa gaaaataaaa agcttaagaa atttaaaatg ctagctgctc     2460

aagagttttc agtagaatat ttaagaacta attttctgca gcttttagtt tggaaaaaat     2520

attttaaaaa caaaatttgt gaaacctata gacgatgttt taatgtacct tcagctctct     2580

aaactgtgtg cttctactag tgtgtgctct tttcactgta gacactatca cgagacccag     2640

attaatttct gtggttgtta cagaataagt ctaatcaagg agaagtttct gtttgacgtt     2700

tgagtgccgg ctttctgagt agagttagga aaaccacgta acgtagcata tgatgtataa     2760

tagagtatac ccgttactta aaaagaagtc tgaaatgttc gttttgtgga aaagaaacta     2820

gttaaattta ctattcctaa cccgaatgaa attagccttt gccttattct gtgcatgggt     2880

aagtaactta tttctgcact gttttgttga actttgtgga aacattcttt cgagtttgtt     2940

tttgtcattt tcgtaacagt cgtcgaacta ggcctcaaaa acatacgtaa cgaaaaggcc     3000

tagcgaggca aattctgatt gatttgaatc tatatttttc tttaaaaagt caagggttct     3060

atattgtgag taaattaaat ttacatttga gttgtttgtt gctaagaggt agtaaatgta     3120

agagagtact ggttccttca gtagtgagta tttctcatag tgcagcttta tttatctcca     3180

ggatgttttt gtggctgtat ttgattgata tgtgcttctt ctgattcttg ctaatttcca     3240

accatattga ataaatgtga tcaagtcaag ga                                   3272


<210>  1766
<211>  2370
<212>  DNA
<213>  homo sapiens

<400>  1766
cgcagccact gaaccacaag cagcttcgcg ttaactggag tgcctgggag tcgcgtgcca       60

ggagccgcac ggccagggac tgactgacag acagacacgc accaccacca caacacacga      120

gacccgggcg ggccgccgcc gccgccgccg gggctcttgg caaactcgcc ggtcgcagag      180

gtcccccgcg gagctgcgcc acagtagcgc cgggcttgca gctttcacgc cgggcgaagg      240

acccggcgct gcgctcgcag ctgcgcggag attcccggca caggccaaag tcacagcaac      300

gctgaggcac agttagagcc aactaagatg ttcgtcaaat ccgagacctt ggagttgaag      360

gaggaagagg acgtgttagt gctgctcgga tcggcctccc ccgccttggc ggccctgacc      420

ccgctgtcat ccagcgccga cgaagaagag gaggaggagc cgggcgcgtc aggcggggcg      480

cgtcggcagc gcggggctga ggccgggcag ggggcgcggg gcggcgtggc tgcgggtgcg      540

gagggctgcc ggcccgcacg gctgctgggt ctggtacacg attgcaaacg gcgcccttcc      600

cgggcgcggg ccgtctcccg aggcgccaag acggccgaga cggtgcagcg catcaagaag      660

acccgtagac tgaaggccaa caaccgcgag cgaaaccgca tgcacaacct caacgcggca      720

ctggacgcgc tgcgcgaggt gctccccacg ttccccgagg acgccaagct caccaagatc      780

gagaccctgc gcttcgccca caactacatc tgggcactca ccgagaccct gcgcctggcg      840

gatcactgcg ggggcggcgg cgggggcctg ccgggggcgc tcttctccga ggcagtgttg      900

ctgagcccgg gaggagccag cgccgccctg agcagcagcg gagacagccc ctcgcccgcc      960

tccacgtgga gttgcaccaa cagccccgcg ccgtcctcct ccgtgtcctc caattccacc     1020

tccccctaca gctgcacttt atcgcccgcc agcccggccg ggtcagacat ggactattgg     1080

cagcccccac ctcccgacaa gcaccgctat gcacctcacc tccccatagc cagggattgt     1140

atctagagct gccatttctg ctacccacgc caggccttag tgggttccct ttcctgtccc     1200

cagtcgagcc ctcctccctt cccctgcccc tcctttccac gccctggaaa ccatctcact     1260

tcacagggca ggtgtagcct ttctgattcc tcggttgttt cttgcatttc ttggctttgg     1320

gtatccttca ttcagacggg ctctgattta ctgaaggtgt gatggagctt attgtcaaag     1380

ccaagggtgg cgttttgggg gcgcttcttg agacgaaaaa gaccctggga agagatgatg     1440

gtggcatatc taaagagttt gcagagcgga ctgacgctcc tcccctttct ctttaacgcc     1500

gaaggacttg gtgcagttcg tgtgaatctc acagggggaa tgcaactggt tcctgtgatc     1560

tcttcacctt tgcttctaca tagagatgtt aatgtcgagt agaaagaaat gtatcttagc     1620

atctgaatga ttttgctggt aataatatta tccacagatt tgcaatggct ggcatctgct     1680

ttattcccat tgctgtctgc aggctgtggg aatttcacct gtcaaaccaa acttccctct     1740

ctgatgtgca ctttgttctg tttcccagat tcgtcacaat gcctattgtc ctgtccttct     1800

ctttcctttt tcttccccat tttgccatct gtctcttatg atttataagg ggaaaaaaac     1860

ttgttttgtt agaggggcag gttagaagtc attgtataat ttgtaggctt tgtaatgatt     1920

gaatgcaagc gtggaaattt aggctgaact ctctatcaaa aggaaaaatg tggaggaaaa     1980

gggaaaaatc aggagggagg attgcctcat gtattattta tttcgacctt ttaggggaga     2040

aggaactccc ccattctttc aagagattaa aaataaatca acagtctgaa aacctaagca     2100

gacacggagc attatccgga tcagccacac acgtgttccc ttctatttat tataaagaaa     2160

tttttcatgg gaaaatatgt attttttgta tattctacag agtttattct agtatgtatt     2220

tacatcttga agaacaagaa agttgttctt gtgattaaac tataaataaa ctatctaatt     2280

ttcataaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                                      2370


<210>  1767
<211>  2370
<212>  DNA
<213>  homo sapiens

<400>  1767
cgcagccact gaaccacaag cagcttcgcg ttaactggag tgcctgggag tcgcgtgcca       60

ggagccgcac ggccagggac tgactgacag acagacacgc accaccacca caacacacga      120

gacccgggcg ggccgccgcc gccgccgccg gggctcttgg caaactcgcc ggtcgcagag      180

gtcccccgcg gagctgcgcc acagtagcgc cgggcttgca gctttcacgc cgggcgaagg      240

acccggcgct gcgctcgcag ctgcgcggag attcccggca caggccaaag tcacagcaac      300

gctgaggcac agttagagcc aactaagatg ttcgtcaaat ccgagacctt ggagttgaag      360

gaggaagagg acgtgttagt gctgctcgga tcggcctccc ccgccttggc ggccctgacc      420

ccgctgtcat ccagcgccga cgaagaagag gaggaggagc cgggcgcgtc aggcggggcg      480

cgtcggcagc gcggggctga ggccgggcag ggggcgcggg gcggcgtggc tgcgggtgcg      540

gagggctgcc ggcccgcacg gctgctgggt ctggtacacg attgcaaacg gcgcccttcc      600

cgggcgcggg ccgtctcccg aggcgccaag acggccgaga cggtgcagcg catcaagaag      660

acccgtagac tgaaggccaa caaccgcgag cgaaaccgca tgcacaacct caacgcggca      720

ctggacgcgc tgcgcgaggt gctccccacg ttccccgagg acgccaagct caccaagatc      780

gagaccctgc gcttcgccca caactacatc tgggcactca ccgagaccct gcgcctggcg      840

gatcactgcg ggggcggcgg cgggggcctg ccgggggcgc tcttctccga ggcagtgttg      900

ctgagcccgg gaggagccag cgccgccctg agcagcagcg gagacagccc ctcgcccgcc      960

tccacgtgga gttgcaccaa cagccccgcg ccgtcctcct ccgtgtcctc caattccacc     1020

tccccctaca gctgcacttt atcgcccgcc agcccggccg ggtcagacat ggactattgg     1080

cagcccccac ctcccgacaa gcaccgctat gcacctcacc tccccatagc cagggattgt     1140

atctagagct gccatttctg ctacccacgc caggccttag tgggttccct ttcctgtccc     1200

cagtcgagcc ctcctccctt cccctgcccc tcctttccac gccctggaaa ccatctcact     1260

tcacagggca ggtgtagcct ttctgattcc tcggttgttt cttgcatttc ttggctttgg     1320

gtatccttca ttcagacggg ctctgattta ctgaaggtgt gatggagctt attgtcaaag     1380

ccaagggtgg cgttttgggg gcgcttcttg agacgaaaaa gaccctggga agagatgatg     1440

gtggcatatc taaagagttt gcagagcgga ctgacgctcc tcccctttct ctttaacgcc     1500

gaaggacttg gtgcagttcg tgtgaatctc acagggggaa tgcaactggt tcctgtgatc     1560

tcttcacctt tgcttctaca tagagatgtt aatgtcgagt agaaagaaat gtatcttagc     1620

atctgaatga ttttgctggt aataatatta tccacagatt tgcaatggct ggcatctgct     1680

ttattcccat tgctgtctgc aggctgtggg aatttcacct gtcaaaccaa acttccctct     1740

ctgatgtgca ctttgttctg tttcccagat tcgtcacaat gcctattgtc ctgtccttct     1800

ctttcctttt tcttccccat tttgccatct gtctcttatg atttataagg ggaaaaaaac     1860

ttgttttgtt agaggggcag gttagaagtc attgtataat ttgtaggctt tgtaatgatt     1920

gaatgcaagc gtggaaattt aggctgaact ctctatcaaa aggaaaaatg tggaggaaaa     1980

gggaaaaatc aggagggagg attgcctcat gtattattta tttcgacctt ttaggggaga     2040

aggaactccc ccattctttc aagagattaa aaataaatca acagtctgaa aacctaagca     2100

gacacggagc attatccgga tcagccacac acgtgttccc ttctatttat tataaagaaa     2160

tttttcatgg gaaaatatgt attttttgta tattctacag agtttattct agtatgtatt     2220

tacatcttga agaacaagaa agttgttctt gtgattaaac tataaataaa ctatctaatt     2280

ttcataaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                                      2370


<210>  1768
<211>  2568
<212>  DNA
<213>  homo sapiens

<400>  1768
cgcgcgcgca gtcgcgcgcg ggtcgtgccg taccaccgtc gcgggcaggc tcggccacga       60

gcgccagagc cccgcgcctc ccctcgcggc ctgtcccaag tccctgcccc gcaacagagc      120

gtcacttccg ccatccccgg cagcggttgg ggcggggcgc acgggggagg gggccaggtc      180

ggagggaagc ccgcccgtgc ccgagcccgc gcccgagcag ggactacatt tcccgagggg      240

cctcggcggc ggctgcggcg acgggcgcgg caacgtcccc cggaagtgga gcccgggact      300

tccactcgtg cgtgaggcga gaggagccgg agacgagacc agaggccgaa ctcgggttct      360

gacaagatgg ccgggctgcc ccgcaggatc atcaaggaaa cccagcgttt gctggcagaa      420

ccagttcctg gcatcaaagc cgaaccagat gagagcaacg cccgttattt tcatgtggtc      480

attgctggcc ctcaggattc cccctttgag ggagggactt ttaaacttga actattcctt      540

ccagaagaat acccaatggc agcccctaaa gtacgtttca tgaccaaaat ttatcatcct      600

aatgtagaca agttgggaag aatatgttta gatattttga aagataagtg gtccccagca      660

ctgcagatcc gcacagttct gctatcgatc caggccttgt taagtgctcc caatccagat      720

gatccattag caaatgatgt agcggagcag tggaagacca acgaagccca agccatagaa      780

acagctagag catggactag gctatatgcc atgaataata tttaaattga tacgatcatc      840

aagtgtgcat cacttctcct gttctgccaa gacttcctcc tctttgtttg catttaatgg      900

acacagtctt agaaacatta cagaataaaa aagcccagac atcttcagtc ctttggtgat      960

taaatgcaca ttagcaaatc tatgtcttgt cctgattcac tgtcataaag catgagcaga     1020

ggctagaagt atcatctgga ttgttgtgaa acgtttaaaa gcagtggccc ctccctgctt     1080

ttattcattt cccccatcct ggtttaagta taaagcactg tgaatgaagg tagttgtcag     1140

gttagctgca ggggtgtggg tgtttttatt ttattttatt ttattttatt tttgaggggg     1200

gaggtagttt aattttatgg gctcctttcc cccttttttg gtgatctaat tgcattggtt     1260

aaaagcagct aaccaggtct ttagaatatg ctctagccaa gtctaacttt atttagacgc     1320

tgtagatgga caagcttgat tgttggaacc aaaatgggaa cattaaacaa acatcacagc     1380

cctcactaat aacattgctg tcaagtgtag attcccccct tcaaaaaaag cttgtgacca     1440

ttttgtatgg cttgtctgga aacttctgta aatcttatgt tttagtaaaa tattttttgt     1500

tattctactt tgcctttgta cagtttattt tactgtgttt atttcatttt cccaatttga     1560

caatcgtatt ttaaaattga aactgatgga acattctttc ttggtcttca ccatctgaca     1620

aattgaatgg caagaggtgg attttgccag tttcttttca ctgatgcaga tttgtgttaa     1680

gatagtactg aatggagtat ttataaactg gccctgagca tgcataaagc atcagtatct     1740

gacctttttt taaccttcta ggaatttgaa ataaatgtgt ttgtgttgtc tgattagatg     1800

atcattggtg tcttgccaca atgtttaaaa attactgtac aggaaagtca cagcaaagat     1860

agcagttgtg actgacatgt aggactttca cagttgtgcc acatttttgc ctaaaatttg     1920

ggttatgaca tttttcttgg ttcttatctg aaaatttcat ctgtaacctt tcatgtgtgt     1980

taagaaacac tgatctgatc atttgggatt tgctgaggca tttgtgagtc ttccttataa     2040

acctgatgag cagatctcaa ctatctagct tgtgtgtcat cagaaaggtt tatccctttg     2100

agagtatcaa gtcctcagtt aatgattctt gctttcatcc ctccagtatt tgctgtggga     2160

gctcgtttta ttctttaatt tggaattcag taatttttct tctttattga cgaattcctc     2220

ccctcacaaa actgttcttt cccacctctc tccatatcta attcctgatt cttgttattt     2280

ttaagtcata aatgtagcca gtcataaata cataaatgtt aaccttcggg ttgcaacctt     2340

gtctcttgca gtttaaggta atggatattg tagcccattt gaattttctt cactcttatt     2400

ctcgtaattc tggagtttct tcagattgtg gtgtatttta ttgtgctcct atgtaagatg     2460

aagaattaac tattaaaatt acattttcaa catacaaaag cttttgatga ctggtaactg     2520

gtatccttcc aaataaatgc attgcttggt aaaaaaaaaa aaaaaaaa                  2568


<210>  1769
<211>  935
<212>  DNA
<213>  homo sapiens

<400>  1769
agtcagaggt cgcgcaggcg ctggtacccc gttggtccgc gcgttgctgc gttgtgaggg       60

gtgtcagctc agtgcatccc aggcagctct tagtgtggag cagtgaactg tgtgtggttc      120

cttctacttg gggatcatgc agagagcttc acgtctgaag agagagctgc acatgttagc      180

cacagagcca cccccaggca tcacatgttg gcaagataaa gaccaaatgg atgacctgcg      240

agctcaaata ttaggtggag ccaacacacc ttatgagaaa ggtgttttta agctagaagt      300

tatcattcct gagaggtacc catttgaacc tcctcagatc cgatttctca ctccaattta      360

tcatccaaac attgattctg ctggaaggat ttgtctggat gttctcaaat tgccaccaaa      420

aggtgcttgg agaccatccc tcaacatcgc aactgtgttg acctctattc agctgctcat      480

gtcagaaccc aaccctgatg acccgctcat ggctgacata tcctcagaat ttaaatataa      540

taagccagcc ttcctcaaga atgccagaca gtggacagag aagcatgcaa gacagaaaca      600

aaaggctgat gaggaagaga tgcttgataa tctaccagag gctggtgact ccagagtaca      660

caactcaaca cagaaaagga aggccagtca gctagtaggc atagaaaaga aatttcatcc      720

tgatgtttag gggacttgtc ctggttcatc ttagttaatg tgttctttgc caaggtgatc      780

taagttgcct accttgaatt tttttttaaa tatatttgat gacataattt ttgtgtagtt      840

tatttatctt gtacatatgt attttgaaat cttttaaacc tgaaaaataa atagtcattt      900

aatgttgaaa aaaaaaaaaa aaaaaaaaaa aaaaa                                 935


<210>  1770
<211>  6732
<212>  DNA
<213>  homo sapiens

<400>  1770
agcattcaaa ccttgcagag ctttgctctc agagagtttg taaaaagaca cactcctctt       60

acaagagttc atgctaccac atagcaaaga accttaaatt tttggaagaa caatatattc      120

attttggcat tgtgcagagc aaagtaaact cggtggcctc ttcttctcca cccctcaaaa      180

tgatagcaat ctctgccgtc agcagtgcac tcctgttctc ccttctctgt gaagcaagta      240

ccgtcgtcct actcaattcc actgactcat ccccgccaac caataatttc actgatattg      300

aagcagctct gaaagcacaa ttagattcag cggatatccc caaagccagg cggaagcgct      360

acatttcgca gaatgacatg atcgccattc ttgattatca taatcaagtt cggggcaaag      420

tgttcccacc ggcagcaaat atggaatata tggtttggga tgaaaatctt gcaaaatcgg      480

cagaggcttg ggcggctact tgcatttggg accatggacc ttcttactta ctgagatttt      540

tgggccaaaa tctatctgta cgcactggaa gatatcgctc tattctccag ttggtcaagc      600

catggtatga tgaagtgaaa gattatgctt ttccatatcc ccaggattgc aaccccagat      660

gtcctatgag atgttttggt cccatgtgca cacattatac gcagatggtt tgggccactt      720

ccaatcggat aggatgcgca attcatactt gccaaaacat gaatgtttgg ggatctgtgt      780

ggcgacgtgc agtttacttg gtatgcaact atgccccaaa gggcaattgg attggagaag      840

caccatataa agtaggggta ccatgttcat cttgtcctcc aagttatggg ggatcttgta      900

ctgacaatct gtgttttcca ggagttacgt caaactacct gtactggttt aaataagttt      960

accttttcct ccaggaaata taatgatttc tgggaacatg ggcatgtata tatatatatg     1020

gagagagaat tttgcacata ttatacatat tttgtgctaa tcttgttttc ctcttagtat     1080

tcctttgtat aaattagtgt ttgtctagca tgtttgttta atcctttgaa atatttgaaa     1140

catcaatttc tattttctga cctctaagcc taaattaaga tattgtatat gtaatgatga     1200

catagttgat gcatccaatc ctaaaactta cattccaaag gaattatatc attatgttcc     1260

taaggagtaa atatatattt gacctgtaag tgtgtgtatg tatacatata catatgtatg     1320

tgtatggatt tatatatgca cacaaacata taatatgtga tgtaacatgt agatgataat     1380

atgattcagt agtcaacttg agggaaattt ttaaaaaact attctcaatt atatacgagg     1440

tgatgggact tcttaacaca catttctata atacccatga aatgataatt tgtaaaataa     1500

cacttagtga tatctggaaa taataattca attaagcaac cacgaatttc accctggaga     1560

tattttttct tatttgagtc caccaaagga taatgccaac ttatataagt tctcaaatca     1620

tgccttccgc ttagtctcat tttattcatt cagtcgtcat gagttgagtg cttactacat     1680

gcaaggcact ctgctagtta tattctaata atgcagagat aattagacat ggttcccgcc     1740

ctcaagaagc tcacaaaagt attcaggaaa taatgcagac tagtgatttt gctataaaat     1800

tatttttgaa ggaagcagac acagcagtat ttacctgtag gtggagcaag taataagcca     1860

tgctgtgcaa tatatacata aagcttctgc ttctcatggg aatttagtta cagtgcttgg     1920

aatgagaagg ggaaggaaag aattaacaaa tgccaagatt tctggagcag attgtacagc     1980

tgtgactttg gaaaacagaa agtaagaccc tcagaaaacc aatgaagtct aagagaaata     2040

aaatttagtg gacaggtatg aaaagtgtaa ttgcgcctaa ctaccagatg gagagcttca     2100

gaatgggcta tccttagagt ctagtacatc ttgaggcctc tcagcaggag acaaaggatt     2160

ccaaaaagag atgtggaggt gctgagggca cctctatctc tttgttgttt agtctgtcat     2220

tgaatcaatc tacttatcat cttgggtctt tgagtattgt atgaaagatc cttcgtgcac     2280

accacacaca gtcatgattt tgttaaagta gccttcttca gatgcttttc taagggctag     2340

ttaccaactt tatttctgtg tttctgtaga agaaacattt tcagttcttc attgagtttg     2400

attatggaaa tccattcaaa gtcactatga aaattttact catgtagttt ggaaatgcaa     2460

cattttccta tcatgaaatc tctttcagag aggagaatac aacatcttag tccagacatt     2520

taacatactg catttcaagt acatgtgtgt gtgttttatt caggttgtgt aatgctcccg     2580

tagaattata gaacaattaa atatggttag ttccagagtg caaattacag aaggaagcta     2640

cttgtttaaa attccataca cgtttgcagt ttcttgtaca catttggata ctttgaaaga     2700

tgacagattg ttaaatccat tcaatggtaa agaaactcac catctggaga ttgagtctac     2760

ttgttaatga atgactagcc caattatcct tataaattga atatggtgac caaatgcttt     2820

gatatcatac tactctgcct ttgtgggcac atatgtagac actactaaaa ataaatattt     2880

ttggagatta aaatggagaa tagaagtaat tacattattt aggtcttaat ccaacttttt     2940

tctaatatat ctaaacaatt gaaagggaag cttattcatg gaatattggc ttgatttatc     3000

tagaaagttt ttccttcttc aattttacta tattcattct acaggaacag caataagtac     3060

tattaaacag aagatggcta cactaagttc caattttgtt gctgaattgc ttctgtgagt     3120

tcacttttca gttctaagga agaataatat ttgctacata tttcacaggg gttcttatga     3180

aggtaaattt accagattaa taaaaattta tgaatattaa aattatcatt aataatataa     3240

aacacttatt tgagattaaa ttaaattttt catgagcccc tctttggcag gaactctgtt     3300

taattctttg tatttatccc agcttcttaa atggtggctg taacataata aatgtttaat     3360

aaatgcttat atgaatggat ttttagaatt aactaagaag ccaaaaatgg caacaattta     3420

cagaaatccc acctttccat gcttaagaca aaaatgtctt aaatataaag ctgtgattat     3480

atcaaaaatc cagataaatc atcaaatata tcagattaag accagggttt acacacttag     3540

gcaatagtcc tttccaaacc atgacaaaaa ctacaagttt atttataatt taacaactca     3600

gctgaaaata taacgggtat atttgttatt ctaactctat tttttaaagt taataatata     3660

aagtggccat gtaaaatatt ttattttcca ggctaaagca aatgaaagtt tgctggtatc     3720

aacacagcct gccatatttt tcacagcatg caacaatggt gctaggatag ctatttctta     3780

ctgtaattgc cagaggcaga aatggtctgg gtataagcta tttcataaaa gcagctttaa     3840

attgtcagta ttaaggtttt catgtggaaa ggtgtcattc aaaaaaaaag taattggcat     3900

acatattcca catcatcgat cctctctgtg gtgttaattt ttttatatga ccagtagaaa     3960

aattttaata ttctcacaat ataggttttg gggcttccat atcatcaaaa gactgaaaaa     4020

ttataatttt agaattaaac tgatggattt cattatagaa ttatctgtga gttgtgtaga     4080

cacagtctta atgtttctgg ttatgacaga taagtttgct caaaaaatgt ggatgaagcc     4140

attattgtta ttattgttat tgcttctgtt cagttgtcta agtatcatcc cttctgtggc     4200

ccatcacgca gcagagttgc cctacaaatt tcatttggca gcgccataac attcatttaa     4260

aaagtttatg aaaacattca tttgaaagtt ccatgcagct ttagcacaga gttgaccaaa     4320

cactggcgta agttcaattt acacagaata tttgaattga aacaatagaa atttttctca     4380

taatatatac ctatgtgaaa ccaacttatc tgcataatta aatctaatac atatttaagc     4440

cagtttaagt gctttgtgtt gatgccatgc ttatcaaata catgcacaag ctaaacataa     4500

tttgaatggg tctatgaagg aaaaataatg cttagacttt ggtgtaggtt cttcctgtgt     4560

agccatatac ccaggctctg cagtatcgaa ggatgcaaat gttgacatag atggaagctc     4620

ttacctacca aagtgtttag gaaggataaa gttacatttg tcttaatttc taacattatc     4680

tttgctttta tgtttcataa aaatttgtca ttatttatgc tggtgaaacg tataatcaca     4740

tccaattatt tgaacacatg caaaataatt ttttaaatta tgttattgtt taaatttgac     4800

ttatgggaga tcagtcaaaa acttagaagg tttaacactt cactgattaa tggtgctgaa     4860

aacacgttac aattaccaca tatccttgct ataagttttg aagtttctta gcaattaaag     4920

tttttttatt cagtgtgaac tgtcagtatc tattctggtg ctaaatgtat ggtgctaaat     4980

gaattgttag tgttgatggc tttagtaatg ctccttttat tcattgctaa atttagtgtt     5040

atccatttga ttcctgattc agaaatatca ataaaatcct atgttaaatt aatctttacc     5100

aaaaacaggc aagttaactc tgttgtttta attcaacagt ccaacattat ttaggtgtta     5160

cagagtgtaa atatatttct ttgggagtta ttttcttttt aaaatctttt tatagcttgg     5220

caatgtccaa agtcaaatat cacctaaact ggttagatta cttctacagc taataatatt     5280

gcaggcactg gcgccctctg gtggttatga agacaaattc ttaatggcta cttgacctac     5340

agcaaaagcc atttctgtac cataaaaatt tgttgtgcaa tattagaatt atcatatgtt     5400

tcctacatct gacagcacct aaaatgtttg ataatattaa catgtatcta agaggaaaaa     5460

agagttaata tattctggca cccactttcc tagtaatgtt ttccatgatt ttccagttct     5520

gaggcactta ttaaagtgct tttttttttc tgaattaatt aggtattggt aaaatatatt     5580

tttaaattta gttagcttta taaacacaat tagaattaca attaattaac agaggtataa     5640

ttgtctcact ttcagaagtg atcatttatt tttatttagc acaggtcata agaaaaatat     5700

atagaaaaat aatcaatttc atatataaaa ggattatttc tccaccttta attattggcc     5760

tatcatttgt tagtgttatt tggtcatatt attgaactaa tgtattattc cattcaaagt     5820

ctttctagat ttaaaaatgt atgcaaaagc ttaggattat atcatgtgta actattatag     5880

ataacatcct aaaccttcag tttagatata taattgactg ggtgtaatct cttttgtaat     5940

ctgttttgac agatttctta aattatgtta gcataatcaa ggaagattta ccttgaagca     6000

ctttccaaat tgatactttc aaacttattt taaagcagta gaaccttttc tatgaactaa     6060

atcacatgca aaactccaac ctgtagtata cataaaatgg acttacttat tcctctcacc     6120

ttctccagtg cctaggaata ttcttctctg agccctagga ttgattctat cacacagagc     6180

aacattaatc taaatggttt agctccctct tttttctcta aaaacaatca gctaataaaa     6240

aaaaaatttg agggcctaaa ttatttcaat ggttgtttga aatattcagt tcagtttgta     6300

cctgttagca gtctttcagt ttgggggaga attaaatact gtgctaagct ggtgcttgga     6360

tacatattac agcatcttgt gttttatttg acaaacagaa ttttggtgcc ataatatttt     6420

gagaattaga gaagattgtg atgcatatat ataaacacta tttttaaaaa atatctaaat     6480

atgtctcaca tatttatata atcctcaaat atactgtacc attttagata ttttttaaac     6540

agattaattt ggagaagttt tattcattac ctaattctgt ggcaaaaatg gtgcctctga     6600

tgttgtgata tagtattgtc agtgtgtaca tatataaaac ctgtgtaaac ctctgtcctt     6660

atgaaccata acaaatgtag ctttttaaag tccattgtat tgttttttct ttcaataaaa     6720

gagtataatt aa                                                         6732


<210>  1771
<211>  4535
<212>  DNA
<213>  homo sapiens

<400>  1771
gcgcgcgtgg aggcgggcgg cgggcgcaca gcagcagccc gggcggtggg cagccaggag       60

cccccggccc ggcccggccc ggcccgccga gggccccagc gcaggagccg cgcccggacc      120

caggcgatgc cctcctagct agccgtcacg ggatggaggg cttcatggac tcagggacac      180

agacggacgc cgtggtggtg ctgtccttgg ctcaggccgc cgtgcttggc ctggtctccg      240

aaaatgagct ctttggagct accataagcg ccgaggcctt ctacccggac ctggggcccg      300

agctttcagg ggcagccatg ggagagcccg agccaccagg ccccgacgtc taccagctgg      360

cctgcaacgg gagggccttg gaggagccgg cggaggagga ggtgctggag gtggaggcag      420

cctgtgagaa gcacacccgg cggaagacgc ggccacctgt gcggttggtg cccaaggtca      480

agttcgagaa ggtggaggag gaggaacagg aggtctatga ggtttctgtg ccaggtgacg      540

acaaggacgc agggccagca gaagcccccg ccgaggcggc cagtggcggc tgcgacgccc      600

tggtgcagag cagcgccgtc aagatgatcg acctcagcgc cttcagccgc aagccccgga      660

cgctccggca tctgccccga accccgaggc cggagctgaa cgtggcccca tatgaccctc      720

acttcccggc cccggcccgg gatggcttcc ccgagcccag catggcgctg cctgggccag      780

aggccttgcc cacagagtgt gggttcgagc caccccacct ggcccccctg agtgaccccg      840

aggcccccag catggagtcc ccggagcctg tcaagccgga acagggcttc gtgtggcagg      900

aggccagtga gttcgaggct gacacggcgg gttcgaccgt ggaacgccac aagaaggccc      960

agctggatcg gctggacatc aacgtgcaga ttgacgactc ctatctggtg gaggcgggcg     1020

accgccagaa gcgctggcag tgccgcatgt gcgagaagtc ctacacgtcc aagtacaacc     1080

tggtgacgca catcctgggc cacaacggca tcaagccaca ctcgtgccca cactgcagca     1140

agctcttcaa gcagcccagc cacctgcaga cgcacctgct gacgcaccag ggcacccggc     1200

cccacaagtg ccaggtatgc cacaaggcct tcacgcagac cagccacctc aagcgccaca     1260

tgctgctgca ctcggaggtc aagccctaca gctgccactt ctgcggccgc ggcttcgcct     1320

accccagcga gctcaaggcc cacgaagtga agcatgagag tggccgctgc catgtctgcg     1380

tcgagtgcgg cctggacttc tccaccctga cccagctcaa gcgccacctg gcctcccacc     1440

agggccccac cctctaccag tgcctcgagt gtgacaagtc cttccactac cgcagccagt     1500

tgcagaacca catgctcaag caccagaacg tgcgaccctt cgtgtgcact gaatgcggca     1560

tggagttcag ccagattcac cacctcaagc agcactccct cacccacaag ggcgtgaagg     1620

agttcaagtg cgaggtgtgt ggccgggagt tcaccctaca ggcgaacatg aagcggcaca     1680

tgctgatcca caccagcgtc cggccctacc agtgccacat ctgcttcaag acctttgtac     1740

agaagcagac tctcaagacc cacatgattg tacactcgcc cgtgaagcca ttcaaatgca     1800

aggtgtgcgg gaagtccttc aaccgcatgt acaacctgct gggccacatg cacctgcacg     1860

ccggcagcaa gcccttcaag tgcccctact gctccagcaa gtttaatctc aagggcaacc     1920

tgagccggca catgaaggtc aagcatggcg tcatggacat cggcctggac agccaagacc     1980

ccatgatgga gctgacaggc actgaccctt cagagctcga cggccagcag gagatggagg     2040

acttcgagga gaacgcctac agctatgcga gcgtggacag cagcgccgag gccagtgtcc     2100

tcactgaaca ggccatgaaa gagatggcct actacaatgt gctatagcgc aagctgggcc     2160

acccctaacg ggggccgggg gcgagggcat gggggtgaga cccatgggct gcaggctgca     2220

cctcctgcag ccgagaaaca agctactgcc ccactgttct gagccctccc tccccgagtc     2280

atttgcacca ctagggacct ttagaccaaa tggagactgt actactggcc ccggctgtga     2340

gccagcacag gcccaggcat cccagcaagg gaaggagaac acgcgaggcc cagatctggg     2400

tctccctggc ctgcttccgt ggggagtggg agaagtgggg ccactgggga caggtcacaa     2460

gggcaccggc cctcggggtc tctccaggcc cagcagagct cttcaggggt cctgacactg     2520

gaagaagaga ccacttgagc catgtctttt tcacggccaa ctcctgcctc taaggatgtc     2580

tgagctcccc tctggccagt actgcccacc tctaccttgt ccaggccccc ttccccgccc     2640

tgtcgacgga ccgccaggca gggcactctg ccttctacct cccggggtct cccatgcgct     2700

cctcaagcca ggtgtgcacg tggccctggc cctggcctgc aggacagctg gggggcaccc     2760

agcccccaga agacccctgt cctacatccc tttctggaag tgagtgtccc tacagtggat     2820

tgcaacacat gtcgtccact tcgaccctag ctggagtgcc tcaccagggg gccccactag     2880

gaacaaagcc aggacaggcc ccgcgtcagg cacacactaa caaaaccaga agcatggggc     2940

agggcagggc ggagtgaggg catcacaggg gaccaagaag ggctgtcctt gggggaggcc     3000

caggaccacc tgtcggggag ggggaccgca gtcatttctc attcctcagt gtccaccttg     3060

cgacggggat agccacgagt cagcagcttc ccggaaagag caacgtattt taaaaaggaa     3120

agtaaagccc acagagggaa atcaagggtt tttttgagca aagggggtct tctgaaggta     3180

acttattatt tttttctttc caactgtgtg tcacctatga ccttttctga tggagatgca     3240

ttttcttttt ccaagcgtaa gcttcctaat gtgctgtgcg tgcttcctac ccacccaccc     3300

cgagcagcct ggccgggcag gactggggct ccatggggac tgtcaccctg gccctggagg     3360

tgcagccgct ggcagcagcc tcagcaggct ggggtgggag gcaggagaag gcagagctgg     3420

gaagccctcc acccctgcct ggctcctgca gtcgctgact tgctctgtcc catgtcccat     3480

cctcggctgt cagggctgct gactctgctc agccaacagc tagctccctc gctcgcctgc     3540

tctcttcccc tctgttccca cgccagctcc tgcccctgga accagagatg acaggcccag     3600

ggcagtgaaa tagcacattc aggaactcta gggcacccgg acccccccac ccacttgcct     3660

cctgaggcct cagtggggag gggcaagcag gggtcttccc caaaggcaca gatgaagcca     3720

ctagcttcag cctagaaacc cggagaaggg aacagcctgc ggtgggagga accaatctgc     3780

agcgcagcca cccccaaggc tggatcctta agtgaaggac caagccaggc ctcagggtga     3840

ctgtgatcag gactgagggg tggacaaggt ggcccaagta tggcttccag accccgaagc     3900

cccacgacct cccaggtgcc cgccatgatg accctcaggt ggcagtgacc ccgtcactgt     3960

ataagacatt ttctcctgct gagcagaagg catcatcccc tgcaactacc tcttcccacg     4020

tctttctccc ctggtaccaa aaagaaccct gtacctctcc tcctcctcct ccctcctgcc     4080

agtgcagtgg ccttggtctt ggaaactgaa gggagaaggt ctggccccca gggtggggct     4140

ctcctttccc tcccccagcc ccgccgtcag cactggccct ctgtgaggtt cgatacttga     4200

acgccccctg ccctgtgcct tggacctggg caaagctagg aggaggaaac agcacaactc     4260

acagtttgag ctggggggtg gtcttggcaa ggctcctgtc tgtacccctc cctaaccttc     4320

tcaaaagagg tgcacagcct ctcgggtgac ttggaaactc ctggacaaat tccattctaa     4380

cttattttga catgtataca aaccaactgt ttagagattc cacttgtgca aagccctact     4440

gtgtttttat gttcctgttt aaaagagaag tttacttagc aataattata aataaatgaa     4500

tattctttag tgaggtgaaa aaaaaaaaaa aaaaa                                4535


<210>  1772
<211>  4202
<212>  DNA
<213>  homo sapiens

<400>  1772
agatgggggc gtctcccggc cttgttgact ttggcgtccg cggggagctg cccctgtgcc       60

cgtggttctc tgcgcatgcc cggaccccgg cggctccgga gtccgggagg ctctggctgc      120

tccagtcgcg ggtccgggcc ccgcctctcc actcggcggt ggcgtccgtg ttgttattgt      180

ggtggtagcg gcgtctggct gctgcggacc ccgccgagtc ctagcgcctg gcctgcgcgc      240

cgctgcccgc gccacaggat taatttattt ttggaaatca agtgcaatat tggaagccat      300

ttctactaat tttatttcac ttttaaattt atgatttgat ttgaatacta tcatgggagg      360

agctgtgagt gctggggaag ataatgatga cttaattgat aatttaaaag aagctcagta      420

tattcgtact gaaagagtgg agcaagcctt cagagcgatt gatcgtggag attactattt      480

ggaaggctac agagacaatg cttacaaaga cttagcctgg aagcatggaa acatccactt      540

gtcagcacct tgcatttatt ctgaagttat ggaagcattg aaacttcaac caggattgtc      600

ttttcttaac ctgggaagtg gaaccggata tttaagtaca atggtgggct taattttagg      660

tccttttgga ataaatcatg ggattgagct tcattcagat gtggtggaat atgccaagga      720

aaaactggag agcttcatca aaaatagtga tagctttgat aaatttgagt tctgtgaacc      780

tgcatttgtt gttggtaatt gcctccagat agcttctgac agtcatcagt atgatcgaat      840

ttattgtgga gctggagtgc agaaagacca tgaaaactac atgaaaatat tactaaaagt      900

tggaggcata ttagtcatgc ctatagagga tcagttaaca cagattatgc gaactggaca      960

gaacacttgg gaaagtaaaa atatccttgc tgtttcattt gctccacttg tgcaaccaag     1020

taagaatgat aatggcaaac cagattctgt gggactccct ccctgtgctg tcaggaatct     1080

acaggacttg gctcgtattt acattcgacg cacacttaga aatttcataa atgatgagat     1140

gcaggccaag gggattcctc aaagggctcc acccaaaagg aaaagaaaga gagttaaaca     1200

gagaattaac acttacgtat ttgtgggtaa tcagcttatt cctcagcctc tagacagtga     1260

agaggatgaa aaaatggaag aggataacaa agaagaggag gaaaaagatc acaatgaagc     1320

aatgaagcca gaggagccac ctcaaaattt actgagagaa aaaatcatga agctgcccct     1380

ccctgaatct ttaaaagctt acttgacata ttttagagac aaataactta gatcaagaag     1440

aaaaatgcct actgataatt cctttagtct tgaaaatgta gcatttgtta ggagttaaaa     1500

gagagaatta tttctttcat cagagcaaat tatagtggaa aaaaaatcac ttgtttctgt     1560

cagtaacaca aatgatgtat tcagtgaata aaagaatccc ttttataaaa tctatttttc     1620

tttaaatctt ggaaaaatgt tgttttagct cagagtgatt tcaaagtgga atgcaacagt     1680

agtcaagact tgtgtactat aaatcctttt ctgattcctt acagatttgt agtgatgagg     1740

tttagattta attttatata tggtttaaat aattgttaag cttatataac ctgatctgaa     1800

ttgcagttgt ttgcatttcc tctatgaaaa cttcatttat ctaataagga agtcaaatgc     1860

tttgtagact atttacctta cttttgttgc aatcactgtt gttgggttgc tgtatatata     1920

ttccgggcaa tatatgagtg caataacaat acaagatatt gaataattta gctttaaaaa     1980

atcccacaaa ttttatgaaa ttttacagcc ctgctacttt tgcttttgaa tctcttgcca     2040

aaagacatgg gtaaaatatc tgcctctctc atagagattt taagagcaca gcaagtgaat     2100

tattaaaaca aagtctatac ttaatacaac tctttatatg gaccctttac attttcagta     2160

tttaaaaaaa tgaggttatc ttaactctat agaattttaa aagtatattt agaattgttt     2220

tttctgtagt tcactgtata aagtatttgg ttttttaaaa aaagcaaaac cattgttatg     2280

tgtgactctt gataggacac agaacgagtg aatgagcatg agtgaggcca ctttcttgga     2340

tggctgtaag tagcagggcc agggtagacc tggtcagcgg atgcacttta gcagatggaa     2400

cttctagttt atctgaatat ttatctttga caaggtaggg ctgagcctac atttgctttt     2460

gatctatcta gtataagaaa tattcacaga aattgtatgt agataccctt tgttttgaaa     2520

atgctgttca gaatcatagt gtaatctttg ggacctatgc catgttcatt tcactccttc     2580

ccatattttt tgtgtttctt ttggtaaaac tataatggtt ttcatttttt acttaatatc     2640

acacagttaa actgtccata tttgagcttt attttagctt atcagtgata aaaaacaggt     2700

agtaactgcc attgtttgtt tgttttccta ataaggcctg aaaacagcca ttccttgtta     2760

agaaagtgta caatgtaaca tatttgctag agttacatgg attatatatt tcttaaaggg     2820

aaaaatttga gagtatcatg gactaccacc agcattatta ttacagtagt tactcagatt     2880

tggttaagga agcccaagca atgtatagtg aaaggattat tatctctctg ctaagattca     2940

gatattgttt cagaaatctc agctccagta attccacaac atctaaaaac aaatgtttgt     3000

gatcatgtgt aagcatgaaa ttgttccaag taagtgagga tattttagtt atgtgaaaga     3060

cagtttcatg gaaggtattt gttttatacc agtggctggg atggtggaat tggggttatt     3120

tctacaatta ttcttagacg attactaaac tgttaagaaa tgccccatat catttttgta     3180

tctaggaaag aaaaaaatca gtttcatact gttgtcatct gtcagaaatg ctcattttat     3240

tttgaattaa atgtggcttt tgaagtacct agttaccttg aattcctggt gaccacatgt     3300

ttttatctgg aaaacctgga gaaagttatc tgtcccatct cccctgcttg tttttttttt     3360

tttttttggt tggagctgct gtttagatga tgcttttact atgcaggaga gagtttttgt     3420

taaggatata tttgaagatt ggcttttcca tattgtcctt cattctttga ccatggcaaa     3480

gtgtacagta gattttcatg atcattgcat atttcttgtc attgaaatgt atcttttatg     3540

tttttaaatg cattcatttt acacttgtga gtttatcatt gactttaaga ggtagaaatg     3600

aaaaatgaaa attaaagcta aagccttttt atctattaat gcagatatat tagaataaga     3660

atattttggg tttgtgttta ttttttaatg aatttatgtt tacttgatat ggaaaattac     3720

gctttatagg tggaaaagta gcaaataaag attaagtaaa agtaagtgaa aatgatgggg     3780

aatatagtat tggaatttta tagctagtta aaacagtaag tatcatctaa tttgggtgtt     3840

tattttgcag atgagaaaac agacctagaa ccgtggcatg ttttgcctga aacatacagt     3900

gagttagaga cagggcctaa gatagcttct agcatcagat caatcccaag aatccatcag     3960

caacctcaga ccaacccaag aagataattt aaatctatac tgcttattgg tcaatatatt     4020

tggttctagt attaataaag aaaaatgtta ttaaaatagc atacatagta gtaaaataaa     4080

atacaaaaag tgtgttgatt tatagctgtt tgagatgata aaagtgaagc aaagcctgtt     4140

aaatcattgg aagacttgga aaattatttt aaataaacaa ttacatgtaa ttaagcattt     4200

tt                                                                    4202


<210>  1773
<211>  4202
<212>  DNA
<213>  homo sapiens

<400>  1773
agatgggggc gtctcccggc cttgttgact ttggcgtccg cggggagctg cccctgtgcc       60

cgtggttctc tgcgcatgcc cggaccccgg cggctccgga gtccgggagg ctctggctgc      120

tccagtcgcg ggtccgggcc ccgcctctcc actcggcggt ggcgtccgtg ttgttattgt      180

ggtggtagcg gcgtctggct gctgcggacc ccgccgagtc ctagcgcctg gcctgcgcgc      240

cgctgcccgc gccacaggat taatttattt ttggaaatca agtgcaatat tggaagccat      300

ttctactaat tttatttcac ttttaaattt atgatttgat ttgaatacta tcatgggagg      360

agctgtgagt gctggggaag ataatgatga cttaattgat aatttaaaag aagctcagta      420

tattcgtact gaaagagtgg agcaagcctt cagagcgatt gatcgtggag attactattt      480

ggaaggctac agagacaatg cttacaaaga cttagcctgg aagcatggaa acatccactt      540

gtcagcacct tgcatttatt ctgaagttat ggaagcattg aaacttcaac caggattgtc      600

ttttcttaac ctgggaagtg gaaccggata tttaagtaca atggtgggct taattttagg      660

tccttttgga ataaatcatg ggattgagct tcattcagat gtggtggaat atgccaagga      720

aaaactggag agcttcatca aaaatagtga tagctttgat aaatttgagt tctgtgaacc      780

tgcatttgtt gttggtaatt gcctccagat agcttctgac agtcatcagt atgatcgaat      840

ttattgtgga gctggagtgc agaaagacca tgaaaactac atgaaaatat tactaaaagt      900

tggaggcata ttagtcatgc ctatagagga tcagttaaca cagattatgc gaactggaca      960

gaacacttgg gaaagtaaaa atatccttgc tgtttcattt gctccacttg tgcaaccaag     1020

taagaatgat aatggcaaac cagattctgt gggactccct ccctgtgctg tcaggaatct     1080

acaggacttg gctcgtattt acattcgacg cacacttaga aatttcataa atgatgagat     1140

gcaggccaag gggattcctc aaagggctcc acccaaaagg aaaagaaaga gagttaaaca     1200

gagaattaac acttacgtat ttgtgggtaa tcagcttatt cctcagcctc tagacagtga     1260

agaggatgaa aaaatggaag aggataacaa agaagaggag gaaaaagatc acaatgaagc     1320

aatgaagcca gaggagccac ctcaaaattt actgagagaa aaaatcatga agctgcccct     1380

ccctgaatct ttaaaagctt acttgacata ttttagagac aaataactta gatcaagaag     1440

aaaaatgcct actgataatt cctttagtct tgaaaatgta gcatttgtta ggagttaaaa     1500

gagagaatta tttctttcat cagagcaaat tatagtggaa aaaaaatcac ttgtttctgt     1560

cagtaacaca aatgatgtat tcagtgaata aaagaatccc ttttataaaa tctatttttc     1620

tttaaatctt ggaaaaatgt tgttttagct cagagtgatt tcaaagtgga atgcaacagt     1680

agtcaagact tgtgtactat aaatcctttt ctgattcctt acagatttgt agtgatgagg     1740

tttagattta attttatata tggtttaaat aattgttaag cttatataac ctgatctgaa     1800

ttgcagttgt ttgcatttcc tctatgaaaa cttcatttat ctaataagga agtcaaatgc     1860

tttgtagact atttacctta cttttgttgc aatcactgtt gttgggttgc tgtatatata     1920

ttccgggcaa tatatgagtg caataacaat acaagatatt gaataattta gctttaaaaa     1980

atcccacaaa ttttatgaaa ttttacagcc ctgctacttt tgcttttgaa tctcttgcca     2040

aaagacatgg gtaaaatatc tgcctctctc atagagattt taagagcaca gcaagtgaat     2100

tattaaaaca aagtctatac ttaatacaac tctttatatg gaccctttac attttcagta     2160

tttaaaaaaa tgaggttatc ttaactctat agaattttaa aagtatattt agaattgttt     2220

tttctgtagt tcactgtata aagtatttgg ttttttaaaa aaagcaaaac cattgttatg     2280

tgtgactctt gataggacac agaacgagtg aatgagcatg agtgaggcca ctttcttgga     2340

tggctgtaag tagcagggcc agggtagacc tggtcagcgg atgcacttta gcagatggaa     2400

cttctagttt atctgaatat ttatctttga caaggtaggg ctgagcctac atttgctttt     2460

gatctatcta gtataagaaa tattcacaga aattgtatgt agataccctt tgttttgaaa     2520

atgctgttca gaatcatagt gtaatctttg ggacctatgc catgttcatt tcactccttc     2580

ccatattttt tgtgtttctt ttggtaaaac tataatggtt ttcatttttt acttaatatc     2640

acacagttaa actgtccata tttgagcttt attttagctt atcagtgata aaaaacaggt     2700

agtaactgcc attgtttgtt tgttttccta ataaggcctg aaaacagcca ttccttgtta     2760

agaaagtgta caatgtaaca tatttgctag agttacatgg attatatatt tcttaaaggg     2820

aaaaatttga gagtatcatg gactaccacc agcattatta ttacagtagt tactcagatt     2880

tggttaagga agcccaagca atgtatagtg aaaggattat tatctctctg ctaagattca     2940

gatattgttt cagaaatctc agctccagta attccacaac atctaaaaac aaatgtttgt     3000

gatcatgtgt aagcatgaaa ttgttccaag taagtgagga tattttagtt atgtgaaaga     3060

cagtttcatg gaaggtattt gttttatacc agtggctggg atggtggaat tggggttatt     3120

tctacaatta ttcttagacg attactaaac tgttaagaaa tgccccatat catttttgta     3180

tctaggaaag aaaaaaatca gtttcatact gttgtcatct gtcagaaatg ctcattttat     3240

tttgaattaa atgtggcttt tgaagtacct agttaccttg aattcctggt gaccacatgt     3300

ttttatctgg aaaacctgga gaaagttatc tgtcccatct cccctgcttg tttttttttt     3360

tttttttggt tggagctgct gtttagatga tgcttttact atgcaggaga gagtttttgt     3420

taaggatata tttgaagatt ggcttttcca tattgtcctt cattctttga ccatggcaaa     3480

gtgtacagta gattttcatg atcattgcat atttcttgtc attgaaatgt atcttttatg     3540

tttttaaatg cattcatttt acacttgtga gtttatcatt gactttaaga ggtagaaatg     3600

aaaaatgaaa attaaagcta aagccttttt atctattaat gcagatatat tagaataaga     3660

atattttggg tttgtgttta ttttttaatg aatttatgtt tacttgatat ggaaaattac     3720

gctttatagg tggaaaagta gcaaataaag attaagtaaa agtaagtgaa aatgatgggg     3780

aatatagtat tggaatttta tagctagtta aaacagtaag tatcatctaa tttgggtgtt     3840

tattttgcag atgagaaaac agacctagaa ccgtggcatg ttttgcctga aacatacagt     3900

gagttagaga cagggcctaa gatagcttct agcatcagat caatcccaag aatccatcag     3960

caacctcaga ccaacccaag aagataattt aaatctatac tgcttattgg tcaatatatt     4020

tggttctagt attaataaag aaaaatgtta ttaaaatagc atacatagta gtaaaataaa     4080

atacaaaaag tgtgttgatt tatagctgtt tgagatgata aaagtgaagc aaagcctgtt     4140

aaatcattgg aagacttgga aaattatttt aaataaacaa ttacatgtaa ttaagcattt     4200

tt                                                                    4202


<210>  1774
<211>  6091
<212>  DNA
<213>  homo sapiens

<400>  1774
gctcgcgcgc ccaacggacc aggctggggc cgtgaggtaa ctgttgcagc cagcggaggt       60

gggaggcgac actgagtctc cagtcccgag aggtgcccga gggaaaagga ggcggcagct      120

aaactggtcc tggagagaag ccccttccgc ccctctcctc agccagcatg tcccggactc      180

cgccgctcct cagtccgcgc ggtggggacc ccgggccgtg gcggccggcg cagccctgac      240

gggttgcgaa ccagggggcg ccccgaacgc gggggttggg gtctgggagc gcgagcggcc      300

gctacggtac gagcggggtg tgctgagtcc cgtggccacc cccggcccca gccatgagga      360

gggacgagcg agacgccaaa gccatgcggt ccctgcagcc gccggatggg gccggctcgc      420

cccccgagag tctgaggaac ggctacgtga agagctgcgt gagccccttg cggcaggacc      480

ctccgcgcgg cttcttcttc cacctctgcc gcttctgcaa cgtggagctg cggccgccgc      540

cggcctctcc ccagcagccg cggcgctgct cccccttctg ccgggcgcgc ctctcgctgg      600

gcgccctggc tgcctttgtc ctcgccctgc tgctgggcgc ggaacccgag agctgggctg      660

ccggggccgc ctggctgcgg acgctgctga gcgtgtgttc gcacagcttg agccccctct      720

tcagcatcgc ctgtgccttc ttcttcctca cctgcttcct cacccggacc aagcggggac      780

ccggcccggg ccggagctgc ggctcctggt ggctgctggc gctgcccgcc tgctgttacc      840

tgggggactt cttggtgtgg cagtggtggt cttggccttg gggggatggc gacgcagggt      900

ccgcggcccc gcacacgccc ccggaggcgg cagcgggcag gttgctgctg gtgctgagct      960

gcgtagggct gctgctgacg ctcgcgcacc cgctgcggct ccggcactgc gttctggtgc     1020

tgctcctggc cagcttcgtc tggtgggtct ccttcaccag cctcgggtcg ctgccctccg     1080

ccctcaggcc gctgctctcc ggcctggtgg ggggcgctgg ctgcctgctg gccctggggt     1140

tggatcactt ctttcaaatc agggaagcgc ctcttcatcc tcgactgtcc agtgccgccg     1200

aagaaaaagt gcctgtgatc cgaccccgga ggaggtccag ctgcgtgtcg ttaggagaaa     1260

ctgcagccag ttactatggc agttgcaaaa tattcaggag accgtcgttg ccttgtattt     1320

ccagagaaca gatgattctt tgggattggg acttaaaaca atggtataag cctcattatc     1380

aaaattctgg aggtggaaat ggagttgatc tttcagtgct aaatgaggct cgcaatatgg     1440

tgtcagatct tctgactgat ccaagccttc caccacaagt catttcctct ctacggagta     1500

ttagtagctt aatgggtgct ttctcaggtt cctgtaggcc aaagattaat cctctcacac     1560

catttcctgg attttacccc tgttctgaaa tagaggaccc agctgagaaa ggggatagaa     1620

aacttaacaa gggactaaat aggaatagtt tgccaactcc acagctgagg agaagctcag     1680

gaacttcagg attgctacct gttgaacagt cttcaaggtg ggatcgtaat aatggcaaaa     1740

gacctcacca agaatttggc atttcaagtc aaggatgcta tctaaatggg ccttttaatt     1800

caaatctact gactatcccg aagcaaaggt catcttctgt atcactgact caccatgtag     1860

gtctcagaag agctggtgtt ttgtccagtc tgagtcctgt gaattcttcc aaccatggac     1920

cagtgtctac tggctctcta actaatcgat cacccataga atttcctgat actgctgatt     1980

ttcttaataa gccaagcgtt atcttgcaga gatctctggg caatgcacct aatactccag     2040

atttttatca gcaacttaga aattctgata gcaatctgtg taacagctgt ggacatcaaa     2100

tgctgaaata tgtttcaaca tctgaatcag atggtacaga ttgctgcagt ggaaaatcag     2160

gtgaagaaga aaacattttc tcgaaagaat cattcaaact tatggaaact caacaagaag     2220

aggaaacaga gaagaaagac agcagaaaat tatttcagga aggtgataag tggctaacag     2280

aagaggcaca gagtgaacag caaacaaata ttgaacagga agtatcactg gacctgattt     2340

tagtagaaga gtatgactca ttaatagaaa agatgagcaa ctggaatttt ccaatttttg     2400

aacttgtaga aaagatggga gagaaatcag gaaggattct cagtcaggtt atgtatacct     2460

tatttcaaga cactggttta ttggaaatat ttaaaattcc cactcaacaa tttatgaact     2520

attttcgtgc attagaaaat ggctatcgag acattcctta tcacaatcgt atacatgcca     2580

cagatgtgct acatgcagtt tggtatctga caacacggcc agttcctggc ttacagcaga     2640

tccacaatgg ttgtggaaca ggaaatgaaa cagattctga tggtagaatt aaccatgggc     2700

gaattgctta tatttcttcg aagagctgct ctaatcctga tgagagttat ggctgcctgt     2760

cttcaaacat tcctgcatta gaattgatgg ctctatacgt ggcagctgcc atgcatgatt     2820

atgatcaccc agggaggaca aatgcatttc tagtggctac aaatgcccct caggcagttt     2880

tatacaatga cagatctgtt ctggaaaatc atcatgctgc gtcagcttgg aatctatatc     2940

tttctcgccc agaatacaac ttccttcttc atcttgatca tgtggaattc aagcgctttc     3000

gttttttagt cattgaagca atccttgcta cggatcttaa aaagcatttt gattttctcg     3060

cagaattcaa tgccaaggca aatgatgtaa atagtaatgg catagaatgg agtaatgaaa     3120

atgatcgcct cttggtatgc caggtgtgca tcaaactggc agatataaat ggcccagcaa     3180

aagttcgaga cttgcatttg aaatggacag aaggcattgt caatgaattt tatgagcagg     3240

gagatgaaga agcaaatctt ggtctgccca tcagtccatt catggatcgt tcttctcctc     3300

aactagcaaa actccaagaa tcttttatca cccacatagt gggtcccctg tgtaactcct     3360

atgatgctgc tggtttgcta ccaggtcagt ggttagaagc agaagaggat aatgatactg     3420

aaagtggtga tgatgaagac ggtgaagaat tagatacaga agatgaagaa atggaaaaca     3480

atctaaatcc aaaaccacca agaaggaaaa gcagacggcg aatattttgt cagctaatgc     3540

accacctcac tgaaaaccac aagatatgga aggaaatcgt agaggaagaa gaaaaatgta     3600

aagctgatgg gaataaactg caggtggaga attcctcctt acctcaagca gatgagattc     3660

aggtaattga agaggcagat gaagaggaat agcgacagtt tgagtaaaag aaaagtcata     3720

ttgaagaagc ccagagggtt gtgcccaggg gcagaaatca ttgcctagtg ttcaccggct     3780

gactctcaac tgaccattcc catgtggaca ggccttaata ctgtgagagg atccttgctc     3840

tgctggcagt ttcccactcc tatgcacttt cacaggaact agaaaactat tcttaaacca     3900

aaaataccat ccgtgttgac ccatgttgca gagcccttac ttaaatcctt cactggtgta     3960

tgaatacttt gtcataatgc tgctttgctg ggtagtgagc tcttattttt cactgggggt     4020

cagctataac taaaaactca agtgacatat ttcagttacc aaagtggcca ggaacttttt     4080

gcttttatga aaatagattc atattgtatt tcccagtgtg tcttttatgt ctttgaatgt     4140

tttggagaaa agtctatgcc tgtctaaaaa tgaatccagt gttgcctttc tgagggattt     4200

ctgctcaatg caatacactg ttcagtgcta ttctcccagc taggtttatc catgaaggac     4260

tgagtgacct ttgttgtatt taacaaaatc caggtgcatc aatttctgat gctttttact     4320

attgtgtatt atctactatg tgtgttttat ttctgctgag agtattcagg tttgccatgg     4380

acatcagaag tttgaattcc agtcttatct tatgttccat ggctgaattt taaagctgtt     4440

taggtttaac aatgaaggga tttattcttt agtcaaaatt gttgttttta ctctagctca     4500

ggattcgtat ttttaaagat ttagttaata tgaacacagc acagatttgt tagaagaaaa     4560

aaaatttgct gtaataccaa aactaacctc atcaaagata cagaaaaaaa gaaatatagt     4620

gagccctaaa ggacacatac attgaataaa taattggaac atgtggttat ctttagatcc     4680

acatcttagc tgtcatttgt tcactctaaa actgatgttc atctttctgt taatttccct     4740

ctgcctaaag actacatgac agaaatgacc tatcactact tattatttct gaagcctaac     4800

tgcaagactg atttctgaga acaagtaaag aactggaata cttatttttc atataaaaat     4860

ctaaatgtgt taataaatca tttcatacaa aagtacatta ttaaataacc acattattaa     4920

aataattgca agaaaatgga ccatatttac aatgttttgt aaacttgcta gtgtgtggat     4980

atgtacccta cttgtgaaat acatttgaag atataaagag cagccaaaat gatggcaaaa     5040

tggtaggcta atattttcta ttattattgg agaacatatc atattttgga atcatgcaat     5100

tttgcacaca gtgaaaccat taattttcca aggtaattcc tttagaatat ggtattggca     5160

tgcagtttct tacttatcta gaatatttgg cttatctgaa agatatcaat ttaagatctc     5220

tggaagtgtt agaatttttg atccttcaca gtgtcaatat ttaatgaatc actaagcttt     5280

atttattaga cgtgttgagt gagtgctgag ttccttgctg ccacttttgt taccattgtc     5340

acacactatg tgtaaaccag tcccaccact tattactaat aaaattttga ctgataattt     5400

atatttgcac ttacaatata tatatcctgt ccttatattt ctctagagta cattttccat     5460

catgtttaag tgtatttctg ctattatttc ctctcctgca gaatacatac aagtgtatgt     5520

gtataaagtc atacatgtac aagcatgcat attgagattg aatcacattt ccatactgtc     5580

tgttatttta ttgggtttta tattgggttt ctttagttta tgttgttttc tcaaaagcag     5640

cattttaaat tacgaatact ggacttattg gatttaatta taaatccaat tactactgga     5700

aactcatttt tacataatat agtccttaaa ttatttaacc cttgctaagt aattgacata     5760

tgtaacaata actagcctaa agaaacccaa aaaagtatct ctcccgagct gaaacttaaa     5820

aattcgtaag tgtaagaaag aatgtgagaa tatattaaat gcacactgta ccattagatg     5880

aaatcttact tgagaaattg ccataagcca tattacagat cttactttgt tactgaatca     5940

gattaatttc ttgttataat aattttcatc ataaattttc tatttttaaa gccgctggta     6000

ctagaaatat tcttttaatg ctatatctat gtacctactg acacattttt ctccataaaa     6060

gtacttttaa aaattacttc atgatttgaa a                                    6091


<210>  1775
<211>  3263
<212>  DNA
<213>  homo sapiens

<400>  1775
agtccgctac ggaggtgagt gcagggctcc gggcgctgtg tgccgtgccc tgtcccccag       60

gctctgggtc cggttgagac gcactcccac cctgggtgct gcagggtctc ccgtggccta      120

cgctgccagg aggcccaggc tgggagaggg agcagggcgg cggcccgggg tgctcttccg      180

cgctcctcga ctccagcttt ggtctttgtg gctcaatagc ttgcgcccat tggaagggga      240

aacgcacgtt gctgtcccag ccacgaggcc ctgagcattt agcacttggt cgacggggga      300

agatgtgtcg gtgcagctaa aagatggaat atttgcgggc gtgaagcggc ccgaggtgat      360

accacaagtc ttttgacatg ctgaggtctg gcaggaacat taacctatgt gcatcccgag      420

tatggaccgt gtgctcccag gctcctgaca tagggtcatg aattagggcc gagtgggagc      480

gcagagcccc tcccagtcac ccggcagcag aagcagcccg gcttttggag gacattgtct      540

cctggagcag tgtcagtccc aaaagctcca gcccttctct gagacgggga ccaggggatg      600

gcagccatgc acctgacagc ctggccccag ggacttcacg gatcccctga agctcatcca      660

tggacttcca tggactacag ggcctgagct atggaattgg ccctagggca gcaggaacct      720

attgtttcag aagtcggtga cctttgagga cgtggctgtg tacttcaccc aggcggaatg      780

ggatggcctg tcccctgcac agaggaccct gtacagggat gtgatgctgg agaattatgg      840

gaatgtggcc tccctgggat ttccacttct caaacctgct gtgatctcac aactggaggg      900

aggaagtgag ctggggggct catctccact ggctgcagga acaggcctcc agggcctcca      960

gactgatatt cagactgaca atgatttgac aaaggaaatg tatgaaggaa aagagaatgt     1020

atcatttgaa cttcaaagag acttttccca ggaaacagac ttttcagaag cctctcttct     1080

agagaaacaa caggaagtcc actcagcagg aaatataaag aaggagaaga gcaacaccat     1140

tgatggaaca gtgaaagatg agacaagccc cgtggaggag tgttttttta gtcaaagttc     1200

aaactcatat cagtgtcata ccatcactgg agagcagccc tctgggtgta caggattggg     1260

gaaatccatc agctttgata caaaactcgt gaagcatgaa ataattaatt ctgaggaaag     1320

acctttcaaa tgtgaagaat tagtagagcc ctttaggtgt gactctcaac ttattcaaca     1380

tcaagagaac aacactgagg aaaagcctta tcagtgttcg gagtgtggca aagctttcag     1440

cattaatgag aaattaattt ggcatcagag acttcacagt ggggagaaac ccttcaaatg     1500

tgtggagtgt gggaaaagct tcagctacag ttcccattat atcacacatc agacaatcca     1560

cagtggggag aagccctatc agtgtaagat gtgtgggaag gccttcagtg ttaatggaag     1620

cctaagtagg catcagagaa tccatacggg agagaagccc tatcagtgca aggaatgtgg     1680

aaatggcttc agctgtagtt ctgcatatat tacacatcag agagtccaca ctggagagaa     1740

accttacgag tgtaatgact gtgggaaagc gttcaatgtt aatgcaaaat taattcaaca     1800

tcagagaatc catactggag agaaacctta tgaatgtaat gaatgtggaa aaggcttcag     1860

gtgcagctcc cagcttaggc agcatcagag catccacaca ggagaaaagc cctatcagtg     1920

taaagagtgt ggaaaaggct tcaataataa tacaaaactc attcagcatc agagaatcca     1980

cacaggtgag aaaccctatg aatgcactga atgtggaaaa gccttcagtg tcaaagggaa     2040

gttaatccaa caccagagaa ttcacacagg cgagaaaccc tatgagtgta atgaatgcgg     2100

gaaagccttc agatgtaact cccaatttcg gcagcatctg agaattcaca ctggggagaa     2160

gccctatgag tgtaatgagt gtggaaaggc cttcagcgtt aatgggaaac taatgcggca     2220

tcagagaatt cacactgggg agaaaccttt tgaatgtaat gagtgtggga gatgctttac     2280

ttctaaaaga aacctacttg atcatcaccg aatccatact ggagaaaagc cctatcaatg     2340

taaggaatgt gggaaagcct tcagtatcaa tgccaaacta actaggcatc agaggataca     2400

tactggggag aaacctttca aatgtatgga atgtgagaaa gcattcagct gtagttctaa     2460

ctatattgtg caccagagaa tccatacagg agagaaaccc tttcagtgta aggagtgtgg     2520

aaaagccttc catgttaatg cccatttaat tcggcatcag agaagccaca ctggggagaa     2580

acccttcaga tgtgtggaat gtggcaaagg cttcagcttt agttctgact acattataca     2640

tcagacagtc cacacttgga agaaacccta tatgtgtagt gtgtgtggga aagcattcag     2700

gtttagcttc cagctcagtc agcatcagag tgtccatagt gaaggaaaat cctaataatg     2760

agaaagatat agaaaactct taaggttaat gccaaaatgg atcaagtatc atcagattca     2820

tccattgaaa aacctccaag agggcatgaa tatggcagag tcttcatatg gaaacagttt     2880

ttattctatt cagtttaaat caggaaagga tgaccagtta aagagaaaca tccaaaaata     2940

gctttgtttt gtaccaacag gaattagaaa atataatgaa aagatttcgt tcccagcagc     3000

atcaagaaaa gtagattttc tagaaataaa cagttatgga ggacttgtat ggagaaattt     3060

aagtcttcac tgagggccac tttacaaagg aaatttgaat aaatggagag agagagaagc     3120

cttgttgttg gataggaaaa cccgtactaa agatactcta cctacattaa tttatttgtt     3180

taatttttga caacaagcat gtattacttt tgaaaagatg aaaaataaag atttatttaa     3240

aaaaggaaaa aaaaaaaaaa aaa                                             3263


<210>  1776
<211>  3555
<212>  DNA
<213>  homo sapiens

<400>  1776
tttcagccaa ccagactgga gcagctgcga gtgctacatc ttggctgtct gaagcgattg       60

gctcctctct ggggagtgga gggtgttcag ttattaatga ccgctgagca ggcagcacca      120

tgtcagtgtg acaactgatc gggtgaacga tgcaccacta accaccatgg aaacaaggaa      180

aaataaagcc agctcacagg atctctcttc actggattga gagcctcagc ctgccgactg      240

agaaaaagag ttccaggaaa aagaaggaat cccggctgca gcctcctgcc ttcctttata      300

ttttaaaata gagagataag attgcgtgca tgtgtgcata tctatagtat atattttgta      360

cactttgtta cacagacaca caaatgcacc tatttatacc gggcaagaac acaaccatgt      420

gattatctca accaaggaac tgaggaatcc agcacgcaag gacatcggag gtgggctagc      480

actgaaactg cttttcaagc atcatgctgc tattcctgca aatactgaag aagcatggga      540

tttaaatatt ttacttctaa ataaatgaat tactcaatct cctatgacca tctatacata      600

ctccaccttc aaaaagtaca tcaatattat atcattaagg aaatagtaac cttctcttct      660

ccaatatgca tgacattttt ggacaatgca attgtggcac tggcacttat ttcagtgaag      720

aaaaactttg tggttctatg gcattcatca tttgacaaat gcaagcatct tccttatcaa      780

tcagctccta ttgaacttac tagcactgac tgtggaatcc ttaagggccc attacatttc      840

tgaagaagaa agctaagatg aaggacatgc cactccgaat tcatgtgcta cttggcctag      900

ctatcactac actagtacaa gctgtagata aaaaagtgga ttgtccacgg ttatgtacgt      960

gtgaaatcag gccttggttt acacccagat ccatttatat ggaagcatct acagtggatt     1020

gtaatgattt aggtctttta actttcccag ccagattgcc agctaacaca cagattcttc     1080

tcctacagac taacaatatt gcaaaaattg aatactccac agactttcca gtaaacctta     1140

ctggcctgga tttatctcaa aacaatttat cttcagtcac caatattaat gtaaaaaaga     1200

tgcctcagct cctttctgtg tacctagagg aaaacaaact tactgaactg cctgaaaaat     1260

gtctgtccga actgagcaac ttacaagaac tctatattaa tcacaacttg ctttctacaa     1320

tttcacctgg agcctttatt ggcctacata atcttcttcg acttcatctc aattcaaata     1380

gattgcagat gatcaacagt aagtggtttg atgctcttcc aaatctagag attctgatga     1440

ttggggaaaa tccaattatc agaatcaaag acatgaactt taagcctctt atcaatcttc     1500

gcagcctggt tatagctggt ataaacctca cagaaatacc agataacgcc ttggttggac     1560

tggaaaactt agaaagcatc tctttttacg ataacaggct tattaaagta ccccatgttg     1620

ctcttcaaaa agttgtaaat ctcaaatttt tggatctaaa taaaaatcct attaatagaa     1680

tacgaagggg tgattttagc aatatgctac acttaaaaga gttggggata aataatatgc     1740

ctgagctgat ttccatcgat agtcttgctg tggataacct gccagattta agaaaaatag     1800

aagctactaa caaccctaga ttgtcttaca ttcaccccaa tgcatttttc agactcccca     1860

agctggaatc actcatgctg aacagcaatg ctctcagtgc cctgtaccat ggtaccattg     1920

agtctctgcc aaacctcaag gaaatcagca tacacagtaa ccccatcagg tgtgactgtg     1980

tcatccgttg gatgaacatg aacaaaacca acattcgatt catggagcca gattcactgt     2040

tttgcgtgga cccacctgaa ttccaaggtc agaatgttcg gcaagtgcat ttcagggaca     2100

tgatggaaat ttgtctccct cttatagctc ctgagagctt tccttctaat ctaaatgtag     2160

aagctgggag ctatgtttcc tttcactgta gagctactgc agaaccacag cctgaaatct     2220

actggataac accttctggt caaaaactct tgcctaatac cctgacagac aagttctatg     2280

tccattctga gggaacacta gatataaatg gcgtaactcc caaagaaggg ggtttatata     2340

cttgtatagc aactaaccta gttggcgctg acttgaagtc tgttatgatc aaagtggatg     2400

gatcttttcc acaagataac aatggctctt tgaatattaa aataagagat attcaggcca     2460

attcagtttt ggtgtcctgg aaagcaagtt ctaaaattct caaatctagt gttaaatgga     2520

cagcctttgt caagactgaa aattctcatg ctgcgcaaag tgctcgaata ccatctgatg     2580

tcaaggtata taatcttact catctgaatc catcaactga gtataaaatt tgtattgata     2640

ttcccaccat ctatcagaaa aacagaaaaa aatgtgtaaa tgtcaccacc aaaggtttgc     2700

accctgatca aaaagagtat gaaaagaata ataccacaac acttatggcc tgtcttggag     2760

gccttctggg gattattggt gtgatatgtc ttatcagctg cctctctcca gaaatgaact     2820

gtgatggtgg acacagctat gtgaggaatt acttacagaa accaaccttt gcattaggtg     2880

agctttatcc tcctctgata aatctctggg aagcaggaaa agaaaaaagt acatcactga     2940

aagtaaaagc aactgttata ggtttaccaa caaatatgtc ctaaaaacca ccaaggaaac     3000

ctactccaaa aatgaacaaa aaaaaaaaaa gcgaaagact gcagttgtgc taaaaacaaa     3060

acaaaacaaa caaacaaaca aaaaagtaaa aaaagattac tttcgagaga gaagtttaag     3120

cttcaccaat gctgctcctg accaatggaa atatgtacaa cttcagcatt ttaagtaact     3180

ggcttcaagg ggtactgtgg caaccaaata aaataactcc attttctaaa actttcatgt     3240

aacttttatg tctggactac agttcaagtg gacaaaaaca tttctgtatt ttttttaagt     3300

aaataagagt agttgaactg agcaatacct cctcctgtgt tgtattacac atattagcca     3360

cgagtttttg cagtgaccag ataaacttga attgacacgt ggtgtaataa aatggacaaa     3420

ttctgtagag tagacacagt gagtatgtgg acctctttta taaggaaaaa tacattttgg     3480

attaaaatca attgcttctg tcttgttttg tttctaaata aagaataatt tctgggaaaa     3540

aaaaaaaaaa aaaaa                                                      3555


<210>  1777
<211>  4562
<212>  DNA
<213>  homo sapiens

<400>  1777
ggttggaatt ttggcgggtt cagctgtgaa cgaagaaggc gtcccggcat cggccaagat       60

tctacattgc tcatctgggc atctgagcct ccttcgaagt ttcctgtcac aactgtcctc      120

ttgacagcat ggatgaggag gaagacaatc tgtctctgct gaccgcactg ctggaagaaa      180

atgagtcagc cttggattgt aattcagaag aaaataactt cttgacgcgg gaaaatggcg      240

agcccgacgc atttgatgag ctctttgatg ccgacggcga cggtgaatct tatacagaag      300

aggctgatga tggagaaaca ggagagacaa gagacgaaaa ggaaaatctg gccactctct      360

ttggagatat ggaggactta acagatgaag aagaagttcc cgcatcacag tcaactgaaa      420

atagggtcct ccctgctcct gcccccaggc gagagaaaac gaatgaagag ttgcaagagg      480

aattaaggaa tttgcaagag caaatgaagg ccttacaaga gcagctaaaa gtaacaacaa      540

ttaaacagac agcaagccca gcccgtctgc aaaaatcccc tgtagagaag tctccccggc      600

cacctcttaa ggagaggaga gttcagagaa ttcaggagtc aacatgcttt tctgcggagc      660

ttgatgtccc tgcgctacca agaaccaaga gggtggctcg aacaccaaag gcttcacctc      720

cagatcccaa aagctcatct tcaaggatga caagtgcacc ctcccaaccc ctacagacga      780

tttctcggaa caaacctagt gggataacta gaggtcaaat tgtggggacc ccaggaagtt      840

ctggggaaac gactcaaccc atctgtgtgg aagccttctc tggtctgcgg ctcaggcggc      900

ctcgagtatc ctccacagaa atgaacaaga aaatgaccgg ccgaaaactg atcagactgt      960

ctcagatcaa ggaaaagatg gccagagaga agctggaaga aatagattgg gtgacatttg     1020

gggttatatt gaagaaggtt acgccacaga gtgtgaatag tggaaaaacc ttcagcatat     1080

ggaaactgaa tgatcttcgt gacctgacac aatgtgtgtc cttgttctta tttggagaag     1140

ttcacaaagc gctctggaag acggagcagg ggactgtcgt agggatcctc aatgccaacc     1200

ccatgaagcc caaggatggt tcagaggagg tgtgtttatc tatcgatcat cctcagaagg     1260

tcttaattat gggtgaagct cttgacctgg gaacctgtaa agccaagaag aagaatggag     1320

agccgtgcac gcagactgtg aatttgcgtg actgtgagta ctgtcagtac catgtccagg     1380

ctcagtacaa gaagctcagc gcaaagcgtg cggatctgca gtccaccttc tctggaggac     1440

gaattccaaa gaagtttgcc cgcagaggca ccagcctcaa agaacggctg tgccaagatg     1500

gcttttacta cggaggggtt tcttctgcct cgtatgcagc ttcaattgca gcagctgtgg     1560

ctcctaagaa gaagattcaa accactctga gtaatctggt tgttaagggc acaaacttga     1620

tcatccagga aacacggcaa aaactcggaa taccccagaa gagcctgtct tgctctgagg     1680

agttcaagga actgatggac ctgccgacgt gtggagccag gaacttaaaa caacatttag     1740

ccaaagccac agcttcaggg attatgggga gcccaaaacc agccatcaag tccatctcgg     1800

cctcagcact cttgaagcaa cagaagcagc ggatgttgga gatgaggaga aggaaatcag     1860

aagaaataca gaagcgattt ctgcagagct caagtgaagt tgagagccca gctgtgccat     1920

cttcatcaag acagccccct gctcagcctc cacggacagg atccgagttc cccaggctgg     1980

agggagcccc ggccacaatg acgcccaagc tggggcgagg tgtcttggaa ggagatgatg     2040

ttctctttta tgatgagtca ccaccaccaa gaccaaaact gagtgcttta gcagaagcca     2100

aaaagttagc tgctatcacc aaattaaggg caaaaggcca ggttcttaca aaaacaaacc     2160

caaacagcat taagaagaaa caaaaggacc ctcaggacat cctggaggtg aaggaacgtg     2220

tagaaaaaaa caccatgttt tcttctcaag ctgaggatga attggagcct gccaggaaaa     2280

aaaggagaga acaacttgcc tatctggaat ctgaggaatt tcagaaaatc ctaaaagcaa     2340

aatcaaaaca cacaggcatc ctgaaagagg ccgaggctga gatgcaggag cgctactttg     2400

agccactggt gaaaaaagaa caaatggaag aaaagatgag aaacatcaga gaagtgaagt     2460

gccgtgtcgt gacatgcaag acgtgcgcct atacccactt caagctgctg gagacctgcg     2520

tcagtgagca gcatgaatac cactggcatg atggtgtgaa gaggtttttc aaatgtccct     2580

gtggaaacag aagcatctcc ttggacagac tcccgaacaa gcactgcagt aactgtggcc     2640

tctacaaatg ggaacgggac ggaatgctaa aggaaaagac tggtccaaag ataggaggag     2700

aaactctgtt accaagagga gaagaacatg ctaaatttct gaacagcctt aaataacccg     2760

aacttcagac attttcccac agacttcctg gcctcctgtg actctggaaa gcaaaggatt     2820

ggctgtgtat tgtccattga ttcctgattg acgccgtcaa aaacaaatgc ttgttaagcc     2880

cataagcttt gcctgcttac tttctgccat tgggttggtt tgataccaca tttaacattg     2940

acatttaagt ggaaaaccaa gttatcattg tcttttctaa gctcagtgtg gatgattgca     3000

ttacttcatt cactgaagtt tttgcccaaa aattggaagg taaacagaga gctatgtttc     3060

tgtatctttt ggttatagag tgttcacttc tttatcataa caaaattcta gtgtttatac     3120

gaacacccag aggcaaaaga atttggctta attctcactc caggtaagta gcttaacttc     3180

tgggcttcag ttttctcatc tgtaaaatca ggaagattgg actaagtgat cctgaaatgt     3240

attttttagc actggatttc tacaaataat aaaactttcc catctagata atgatgatca     3300

catagtcttg atgtacggac attaaaagcc agatttcttc attcaattct gttatctctg     3360

ttttactctt tgaaattgat caagccactg aatcactttg catttcagtt tatatatata     3420

gagagaaaga aggtgtctgc tcttacatta ttgtggagcc ctgtgataga aatatgtaaa     3480

atctcatatt attttttttt taattttttt attttttatg acagggtctc actatgtcac     3540

cctggctgga gtgcagtagt gcgatcgcgg cacactgcag ccttggcttc cctgggctca     3600

agcagtcctc ccacctcagt ctcccaaata gctaggacta caggcgtgcg tgaccaagcc     3660

cagctaattt ttgcattttt tgtagagatg gggttttgcc atgttgctca ggctggtctc     3720

aaactcctga gcactagcaa tccacccacc tctgtttcca aaaaaaaaaa aaaaatgaaa     3780

ggtcaacccc tatgcaaatt accacagcaa aggtttcatt caggagattc ttccatctgg     3840

gcaacctggt tttccaaata tcatttgacc taagtgaatg ttgatactag ctaaagattg     3900

ggtaaattgg ttgaattatt gtattgaagc ttgagctgta gctaaaagta atttaggttt     3960

cccctaagat gttattatgt tagggacata acacttttgg gaggttgttg tgggagatgg     4020

ttgatttagg ttttcaaaag ctagaaataa aatttacatg ccttagattt cataaaattc     4080

tgctctaatt gggtggaagg tgctgtatct aacttgtgtt cctcctaagg ttatgtccta     4140

ataactattc ttttaggagt atacttctac tttatagaag gttgcttttc tttttaattt     4200

tttctaacaa agaaaagaat aaagtattta ttaataagaa ccagaaagca cttgaaactg     4260

atgtttttaa tggctcattt agggtagatt tatttatctc attaacttaa aacagctatg     4320

tgtatgaaat aggtcacaac agaacttgaa caccaggttg gtgtctgagc aatccctttc     4380

ttatgggaaa aacaatgttc ttgtttgaac agagggtatc attgcagtca gtattcacgt     4440

gtatattgtt atataagttg tataatatgc ttgtaaaggc tgagggtgag ctgtatctgg     4500

atgccttttt acaatttgat tttaactttt aaaataaatt taaaacataa aaaaaaaaaa     4560

aa                                                                    4562


<210>  1778
<211>  4928
<212>  DNA
<213>  homo sapiens

<400>  1778
gcggggcgcg gcggcaggaa ctttcccggg gacccctgcg ggaaggcctg gccagtaagc       60

gcgcctcttt ggcccgaatc aacatggaaa cctaaggaaa aacgtctgac ctgcggaggt      120

agtttgggtg gctacttggt gttggacttg gctaaataaa taccagaggc agataaaaca      180

agcgaggggc ctaggtcaag agttccaagt ttgttcctcg ataaaaaacg acaaacgcgg      240

tcgggggcgg tgatgcccgc ctgcagtccc aacactttag gaagctgagg cggggggatc      300

gcaggagttc gagaccagtc tgggcaacat aatgagacca tccccaccac ctcccgtcct      360

taattttttt taataaaaaa aatctttaag tgagaaatgc atctgtaatg tccttattaa      420

ccaaaaacgc ctaagggata aagaagcaca cgctccctag ccaacgctag aggaacacac      480

cccgagagct ggtgctgtag gacccagttt tcccgcgaaa acgctgccgc gcagggggtc      540

agaccatctg gaccaagggg ggccgagcga ggcctacttc tggtttacgc acgggcgctg      600

aaagaagcgg cactgtcccc ccctgccgat gcgcagtggc gcctcccgga ggcggagcca      660

cgtacgagcg ccgctgtgat tggtgaggcc ccgccagggg cggagacgac cttgccgccg      720

gcgggaactc tgggtctcgc ggtttgggag cgctactcgc caggtggact cggagtccgc      780

gagcgtcgtc ggcaagcggc cgcctttcca cggtaaccgc gcgccggcgg ggagggcgtg      840

gcgcggagcc gacgggaacg tccgcgctgc ggagcagggc agggaagccg ggaggcgggc      900

ccggcccgag cttgtccttg tcgcgcaggt actccgagca ctatgtcgtc cccggcgtcg      960

accccgagcc gccgcggcag ccggcgtgga agggccaccc ccgcccagac gcctcggagt     1020

gaggatgcca ggtcatctcc ctctcagaga cgtagaggcg aggattccac ctccacgggg     1080

gagttgcagc cgatgccaac ctcgcctgga gtggacctgc agagccctgc tgcgcaggac     1140

gtgctgtttt ccagccctcc ccaaatgcat tcttcagcta tccctcttga ctttgatgtt     1200

agttcaccac tgacatacgg cactcccagc tctcgggtag agggaacccc aagaagtggt     1260

gttaggggca cacctgtgag acagaggcct gacctgggct ctgcacagaa gggcctgcaa     1320

gtggatctgc agtctgacgg ggcagcagca gaagatatag tggcaagtga gcagtctcta     1380

ggccaaaaac ttgtgatctg gggaacagat gtaaatgtgg cagcatgcaa agaaaacttt     1440

cagagatttc ttcagcgttt tattgaccct ctggctaaag aagaagaaaa tgttggcata     1500

gatattactg aacctctata catgcaacga cttggggaga ttaatgttat tggtgagcca     1560

tttttaaatg tgaactgtga acacatcaaa tcatttgaca aaaatttgta cagacaactc     1620

atctcttacc cacaggaagt tattccaact tttgacatgg ctgtcaatga aatcttcttt     1680

gaccgttacc ctgactcaat cttagaacat cagattcaag taagaccatt caacgcattg     1740

aagactaaga atatgagaaa cctgaatcca gaagacattg accagctcat caccatcagc     1800

ggcatggtga tcaggacatc ccagctgatt cccgagatgc aggaggcctt cttccagtgc     1860

caagtgtgtg cccacacgac ccgggtggag atggaccgcg gccgcattgc agagcccagt     1920

gtgtgcgggc gctgccacac cacccacagc atggcactca tccacaaccg ctccctcttc     1980

tctgacaagc agatgatcaa gcttcaggag tctccggaag acatgcctgc agggcagaca     2040

ccacacacag ttatcctgtt tgctcacaat gatctcgttg acaaggtcca gcctggggac     2100

agagtgaatg ttacaggcat ctatcgagct gtgcctattc gagtcaatcc aagagtgagt     2160

aatgtgaagt ctgtctacaa aacccacatt gatgtcattc attatcggaa aacggatgca     2220

aaacgtctgc atggccttga tgaagaagca gaacagaaac ttttttcaga gaaacgtgtg     2280

gaattgctta aggaactttc caggaaacca gacatttatg agaggcttgc ttcagccttg     2340

gctccaagca tttatgaaca tgaagatata aagaagggaa ttttgcttca gctctttggc     2400

gggacaagga aggattttag tcacactgga aggggcaaat ttcgggctga gatcaacatc     2460

ttgctgtgtg gcgaccctgg taccagcaag tcccagctgc tgcagtacgt gtacaacctc     2520

gtccccaggg gccagtacac gtctgggaag ggctccagtg cagttggcct cactgcgtac     2580

gtaatgaaag accctgagac aaggcagctg gtcctgcaga caggtgctct tgtcctgagt     2640

gacaacggca tctgctgtat cgatgagttc gacaagatga atgaaagtac aagatcggta     2700

ttgcatgaag tcatggaaca gcagactctg tccattgcaa aggctgggat catctgtcag     2760

ctcaatgcgc gcacctctgt cctggcagca gcaaatccca ttgagtctca gtggaatcct     2820

aaaaaaacaa ccattgaaaa catccagctg cctcatactt tattatcaag gtttgatttg     2880

atcttcctct tgctggaccc tcaggacgaa gcctatgaca ggcgtctggc tcaccacctg     2940

gtcgcactgt actaccagag cgaggagcag gcagaggagg agctcctgga catggcggtg     3000

ctaaaggact acattgccta cgcgcacagc accatcatgc cgcggctaag tgaggaagcc     3060

agccaggctc tcatcgaggc ttatgtagac atgaggaaga ttggcagtag ccggggaatg     3120

gtttctgcat accctcgaca gctagagtca ttaatccgct tagcagaagc ccatgctaaa     3180

gtaagattgt ctaacaaagt tgaagccatt gatgtggaag aggccaaacg cctccatcgg     3240

gaagctctga agcagtctgc aactgatccc cggactggca tcgtggacat atctattctt     3300

actacgggga tgagtgccac ctctcgtaaa cggaaagaag aattagctga agcattgaaa     3360

aagcttattt tatctaaggg caaaacacca gctctaaaat accagcaact ttttgaagat     3420

attcggggac aatctgacat agcaattact aaagatatgt ttgaagaagc actgcgtgcc     3480

ctggcagatg atgatttcct gacagtgact gggaagaccg tgcgcttgct ctgaagcctt     3540

gtgagcaagg aaggctccct gcatgtcctg cttgctgcac gccacatggg tgtggtctgc     3600

atctcagttg gccgccatca gtgtaaatag agcttaaagt catggtttgg ctgcataaaa     3660

attttctaac ttgggttcaa tatttgtagt gaagtatctg ttttcatttt tttcacgtta     3720

taaataaaaa tactatgctg gccgggcgcg gtggctcaca cctgtaatcc cagcactttg     3780

ggaggccaat gtgggtggat catgaggtca ggagttcaag accagcctag ccaagatggt     3840

gaaaccccgt ctctagtaaa gataacaaaa aattagctgg gcttgatggc atgcgcctgt     3900

aatcccagct actcgggagg ttgaggcagg agaatcgctt aaacccaggc ggcagaggtt     3960

gcagtgagcc aagatcgcgc cactgcactc cagcctcagc aatagagtga gactgtctca     4020

aaaaaaaaaa aaaaaaaaaa acctgccaat tttcaaacat accgtagaga ttattttcag     4080

gtgccatttt atagtatagc agcagggctt ttactctgtg tatgcacaga tgcagtctgg     4140

ggcatggttt gtgtgctgga ctttctcatg gccatcatca gtatgcttat ggatttgatg     4200

acaggcatag cctgggcata tcacctcatt ggtaaagggc tagagccttt cttttttatg     4260

gcacttcttt ttttgagata gggtcttact ctgtcaccct ggctagagta cactggtaca     4320

atcacggctc aatgtaggct taacctcctg ggctcaggtg tatgtcacta tgcccggcta     4380

ctttttgtat tttttggtag agacggcttc gccacgttgc ccaggctgca agcgatatgc     4440

ctaggctcaa gcgatctgcc cacctcaact tccggaagtg ctgagattac aggtgtgagc     4500

cactgcaccc agcctttgtt ttatttttta ttttttgaga ggtatgattc tttctagaga     4560

ttttttctca tggctactat tagatcagga atgggtgatt ggagattatt agattctagg     4620

ttaacttcta ccactttacc ctaatacata aaactttttc ctaaataaat gatggaagga     4680

ataatacttg gttacctggc attatttttc agtaagaaaa aagctttact aaccactaca     4740

tttatggaaa tttgtagggg taagtatttt ataggtcata aaaaacacca taatataacg     4800

aatctcattt tctttaaatg tgaattaaat cctaacagtc atctttataa aatgaccata     4860

ggctaaaatc ttacgtgtaa gtactactac aataaataat ttctgaaacc tttaaaaaaa     4920

aaaaaaaa                                                              4928


<210>  1779
<211>  1927
<212>  DNA
<213>  homo sapiens

<400>  1779
acgccggcgc tcccaggccg cgcttcctgc gtccccaacc cggtccctga gagggcagtg       60

cgccctctcc accactgcgt tccctcggct aagaatcccc cgaaccccag ccccgcgatc      120

gcggcgccca ccgaggaggc cgcccgggtg gggcgcgggg gtcgcgaagc ccgcagtccc      180

ggaccgccca gccgagacgg agccggaccc gccgcctccc gggcccttcc accgcagcca      240

tccgcacggg aggcctcgcg attgctcgga accatcccgc aggagttcag ctgatatttt      300

ctagtgtggg gcgagagatt ttgtggagcg catttaaggg gtttttgttg tgactgctgc      360

cttgtatata tttattttct ttcttggaac tgggcctcgc cctcctccca ctgacatgat      420

ggcccagtcc aaggccaatg gctcgcacta tgcgctgacc gccatcggcc tggggatgct      480

ggtccttggg gtgatcatgg ccatgtggaa cctggtaccc ggcttcagcg cggccgagaa      540

gccaacagct cagggcagca acaagaccga ggtgggtggc ggcatcctca agagcaagac      600

cttctctgtg gcctacgtgc tggtcggggc cggggtgatg ctgctgctgc tttctatctg      660

cctgagtatc agggataaga ggaagcagcg gcagggcgag gacctggccc atgtccagca      720

cccgacaggc gctgggcctc acgcccagga ggaagacagc caggaggaag aagaggagga      780

tgaggaggct gcctcaaggt actatgttcc cagctacgag gaagtgatga acacaaacta      840

ctcagaagca aggggagagg agcagaaccc gaggttgagc atctctctcc cgtcctatga      900

gtcactgacg gggctcgacg agaccacccc cacatccacc agggctgacg tggaggccag      960

ccctgggaac ccccctgaca ggcagaactc taagttggcc aaacgactga aaccgctgaa     1020

agttcgaagg attaaatctg aaaagcttca cctcaaagac tttaggatca acctcccaga     1080

caaaaacgtc cctcctccct cgatagagcc tttgactcct ccaccgcagt atgatgaagt     1140

ccaggagaag gcccccgaca cccggccgcc cgactgaatg gccccacttg agccacgctc     1200

cctcctgtct ctcacacctt tcacccccaa gactctaaca aagccacatg agccacagtt     1260

gagaagcgga ggggccagct gtgcatggag ccatttggat ggcggcgggc ggggggggat     1320

tctctgtatc aggagtgact ttgttgcccc acacagcctc ctgctgcagg tgctttggaa     1380

agagatgctg ccttggagct ggtgaatctg tggaccacat tcaagggtgt ggcacaggca     1440

tcttcccatc cttttcactc cgaatcgctg gcgacacatt ctcctttcca gctaggaaag     1500

ggttcctcgc ggctggttta gattgtggtt gtttgttttg cttctactaa gactgttttg     1560

tttcaaaaag gaaacaagtt ttgtgtttgc tgtctacgct ggagtcctga actgtgggta     1620

gaaaacacga cctggctttg tagaaaggac acagggctgt tttatgaact aagcggtgag     1680

gctcaggtgg cggctctcgc agagcccctg atgctgttgt tctttgaggg cttaaggcct     1740

gatgaacgta ggcacgtgat gcataatagt cttcaatggt acacttaact agtctcttct     1800

gtgtaacagc aaaaaaaaaa aaaaaaagaa gaagaaagaa aactgtagga aatgttcttt     1860

ttgaaatgcc atgcaatgga gctttttgta ataaaatatt ttatatgtag taaaaaaaaa     1920

aaaaaaa                                                               1927


<210>  1780
<211>  2420
<212>  DNA
<213>  homo sapiens

<400>  1780
ccagccatgc ctcccagcgc gcttcccttc ccccgcctcc tggtcctgca ccctcccctc       60

ccctcccccc gcttcctgcc ttgtgacaca tcccgggccc tcccggaggc ggcagcagca      120

gcagctgcag cggcagcagc ggcagcagag gcagcagcag tagccaccac tccgccgagg      180

ccgcaacccc ggctcggcct ccccaggccc cgccgctgcc gcagtcatgg ctgctgatgg      240

ggtggacgaa cgctcgcctc tgctgtcagc atcccactcc ggaaatgtca ctcccaccgc      300

cccaccgtac ttgcaagaaa gcagccccag agcggagctc ccacctccat atacagccat      360

tgccagtcca gacgccagtg gtattccagt aataaactgc cgtgtgtgcc aatcactaat      420

caatttggat ggcaagcttc accagcatgt ggttaagtgc acagtttgca atgaagctac      480

gccaatcaaa aaccccccaa caggcaagaa atatgttaga tgcccttgta attgtcttct      540

catttgtaag gacacatctc ggcgaatagg atgcccaaga cccaactgta gacggataat      600

taaccttggc ccagtaatgc ttatttctga agaacaacca gctcagcctg cattgccaat      660

ccaaccagaa ggtacaaggg tcgtgtgtgg gcactgtgga aacacattcc tgtggatgga      720

actgaggttc aacactctgg caaaatgccc acactgcaaa aaaatctcct cagtgggtag      780

tgcacttcca cgaagacgct gctgtgcata tattaccatt ggaatgatat gtattttcat      840

tggagttggg ttaactgttg gcaccccaga ttttgcaagg cgatttcgag caacctatgt      900

ttcttgggca attgcttatc tcctaggatt gatctgcctt atccgagctt gttattgggg      960

agccataaga gtcagttatc cagaacacag ttttgcataa gcttgtttat gattcagtaa     1020

tgcaggtgag agtgtctagc agttcttggt aagctactct ggacatcttt aaattattta     1080

tcctaatgga ttccattctg gtttatgtat aatcgtttca agactttggg agtcttttat     1140

gaacaaatgc tcattgcact atattatatg caaattgttt tgctgctagg ttttcaaaat     1200

ttgaataata aagccttttc atgttctttt acatctctta tagatatttt tggatttgtt     1260

accaaacatt acatttactc tcaccctttt attattttta aataagttat ttcattactt     1320

gctgatacat gagtattcct aagtgtttat aaatatttct ataatagttt cacatttata     1380

tttacatttt aattaaacag tatcaaaatt gcttgcttaa aacctaagca atatgcattt     1440

tgcttgaact gcttactgta actttaacct aagattatag tgaccttatt caggaaaaaa     1500

aaaaaaattt agtgtaactt caaagacttg acattcttgt cagaggaaaa aaaatttcta     1560

gatactgttt gcttgttttt tgttgtttgt agaaagataa aatattttgg tagtaattta     1620

aaatacaaga acgaatattt atttgtccac agttggagat gttggataaa tgtcttttct     1680

caaagatcac aggacttttg tctttcattt ttgccttttt atttaccatt tataaaagat     1740

ctggtctgga ttatggaatt taatgtttat cagctctatg tattccttta tagaggcttg     1800

aggaagtatt tcacataaca tgttttataa tacttaacca tttatccaaa gatatattta     1860

cattgggttg tgcccctttc ccttagatca tggtaaattt ttcttattga ggtaattatg     1920

tactacttat atttgaagga agcttatgac attttacagt agctaaaatg ttgagattag     1980

aggtactttt actattcttc tcaaaggtaa ctgatcagat aattacccaa attattcaag     2040

aaaatagatc agaaataaag aacaacataa ttttctaaga attcattgaa atttatggaa     2100

tcagctctcg cactgcccat ctttgcagtt ttgaaaaaga aattgcttaa tcacaaatgt     2160

tctacagtct ttaaatgtag tagaattaga cagtgagatc atctgagtaa attgattggt     2220

gattccagag ataagactaa tattttaaat tatttatgat actgattagt ataaaaacgt     2280

actcatcaca gaatttgaag caaaatacat gtacacttca aagagtaaat gacaaatgta     2340

taaatgctgt agctcaggat tatatgtacc tttaaaaata cactaataaa gattattgtt     2400

caaaaaaaaa aaaaaaaaaa                                                 2420


<210>  1781
<211>  3271
<212>  DNA
<213>  homo sapiens

<400>  1781
agaaggatcc atctaacatt tactgaaata aggaagatgc tttattcaat ctaaaagtga       60

aaaaagaacc ttttagacat tattattata aaatgtctat aagaagactt ctcattttaa      120

tcctcaaaat agggagacga tggactgagc tgatccgcac catggagtct cgggtcttac      180

tgagaacatt ctgtttgatc ttcggtctcg gagcagtttg ggggcttggt gtggaccctt      240

ccctacagat tgacgtctta acagagttag aacttgggga gtccacgacc ggagtgcgtc      300

aggtcccggg gctgcataat gggacgaaag cctttctctt tcaagatact cccagaagca      360

taaaagcatc cactgctaca gctgaacagt tttttcagaa gctgagaaat aaacatgaat      420

ttactatttt ggtgacccta aaacagaccc acttaaattc aggagttatt ctctcaattc      480

accacttgga tcacaggtac ctggaactgg aaagtagtgg ccatcggaat gaagtcagac      540

tgcattaccg ctcaggcagt caccgccctc acacagaagt gtttccttac attttggctg      600

atgacaagtg gcacaagctc tccttagcca tcagtgcttc ccatttgatt ttacacattg      660

actgcaataa aatttatgaa agggtagtag aaaagccctc cacagacttg cctctaggca      720

caacattttg gctaggacag agaaataatg cgcatggata ttttaagggt ataatgcaag      780

atgtccaatt acttgtcatg ccccagggat ttattgctca gtgcccagat cttaatcgca      840

cctgtccaac ttgcaatgac ttccatggac ttgtgcagaa aatcatggag ctacaggata      900

ttttagccaa aacatcagcc aagctgtctc gagctgaaca gcgaatgaat agattggatc      960

agtgctattg tgaaaggact tgcaccatga agggaaccac ctaccgagaa tttgagtcct     1020

ggatagacgg ctgtaagaac tgcacatgcc tgaatggaac catccagtgt gaaactctaa     1080

tctgcccaaa tcctgactgc ccacttaagt cggctcttgc gtatgtggat ggcaaatgct     1140

gtaaggaatg caaatcgata tgccaatttc aaggacgaac ctactttgaa ggagaaagaa     1200

atacagtcta ttcctcttct ggagtatgtg ttctctatga gtgcaaggac cagaccatga     1260

aacttgttga gagttcaggc tgtccagctt tggattgtcc agagtctcat cagataacct     1320

tgtctcacag ctgttgcaaa gtttgtaaag gttatgactt ttgttctgaa aggcataact     1380

gcatggagaa ttccatctgc agaaatctga atgacagggc tgtttgtagc tgtcgagatg     1440

gttttagggc tcttcgagag gataatgcct actgtgaaga catcgatgag tgtgctgaag     1500

ggcgccatta ctgtcgtgaa aatacaatgt gtgtcaacac cccgggttct tttatgtgca     1560

tctgcaaaac tggatacatc agaattgatg attattcatg tacagaacat gatgagtgta     1620

tcacaaatca gcacaactgt gatgaaaatg ctttatgctt caacactgtt ggaggacaca     1680

actgtgtttg caagccgggc tatacaggga atggaacgac atgcaaagca ttttgcaaag     1740

atggctgtag gaatggagga gcctgtattg ccgctaatgt gtgtgcctgc ccacaaggct     1800

tcactggacc cagctgtgaa acggacattg atgaatgctc tgatggtttt gttcaatgtg     1860

acagtcgtgc taattgcatt aacctgcctg gatggtacca ctgtgagtgc agagatggct     1920

accatgacaa tgggatgttt tcaccaagtg gagaatcgtg tgaagatatt gatgagtgtg     1980

ggaccgggag gcacagctgt gccaatgata ccatttgctt caatttggat ggcggatatg     2040

attgtcgatg tcctcatgga aagaattgca caggggactg catccatgat ggaaaagtta     2100

agcacaatgg tcagatttgg gtgttggaaa atgacaggtg ctctgtgtgc tcatgtcaga     2160

atggattcgt tatgtgtcga cggatggtct gtgactgtga gaatcccaca gttgatcttt     2220

tttgctgccc tgaatgtgac ccaaggctta gtagtcagtg cctccatcaa aatggggaaa     2280

ctttgtataa cagtggtgac acctgggtcc agaattgtca acagtgccgc tgcttgcaag     2340

gggaagttga ttgttggccc ctgccttgcc cagatgtgga gtgtgaattc agcattctcc     2400

cagagaatga gtgctgcccg cgctgtgtca cagacccttg ccaggctgac accatccgca     2460

atgacatcac caagacttgc ctggacgaaa tgaatgtggt tcgcttcacc gggtcctctt     2520

ggatcaaaca tggcactgag tgtactctct gccagtgcaa gaatggccac atctgttgct     2580

cagtggatcc acagtgcctt caggaactgt gaagttaact gtctcatggg agatttctgt     2640

taaaagaatg ttctttcatt aaaagaccaa aaagaagtta aaacttaaat tgggtgattt     2700

gtgggcagct aaatgcagct ttgttaatag ctgagtgaac tttcaattat gaaatttgtg     2760

gagcttgaca aaatcacaaa aggaaaatta ctggggcaaa attagacctc aagtctgcct     2820

ctactgtgtc tcacatcacc atgtagaaga atgggcgtac agtatatacc gtgacatcct     2880

gaaccctgga tagaaagcct gagcccattg gatctgtgaa agcctctagc ttcactggtg     2940

cagaaaattt tcctctagat cagaatcttc aagaatcagt taggttcctc actgcaagaa     3000

ataaaatgtc aggcagtgaa tgaattatat tttcagaagt aaagcaaaga agctataaca     3060

tgttatgtac agtacactct gaaaagaaat ctgaaacaag ttattgtaat gataaaaata     3120

atgcacaggc atggttactt aatattttct aacaggaaaa gtcatcccta tttccttgtt     3180

ttactgcact taatattatt tggttgaatt tgttcagtat aagctcgttc ttgtgcaaaa     3240

ttaaataaat atttctctta ccttataaca c                                    3271


<210>  1782
<211>  3208
<212>  DNA
<213>  homo sapiens

<400>  1782
gtgacgcacg gggtggcgcg cgtgggaccc gaggggtggg gctgggttta gtaggagacc       60

tggggcaagg ccccctgtgg acgaccatct gccagcttct ctcgttccgt cgattgggag      120

gagcggtggc gacctcggcc ttcagtgttt ccgacggagt gaatggcggc ggcggctggg      180

atgctgctgc tgggcttgct gcaggcgggt gggtcggtgc tgggccaggc gatggagaag      240

gtgacaggcg gcaacctctt gtccatgctg ctgatcgcct gcgccttcac cctcagcctg      300

gtctacctga tccgtctggc cgccggccac ctggtccagc tgcccgcagg ggtgaaaagt      360

cctccataca ttttctcccc aattccattc cttgggcatg ccatagcatt tgggaaaagt      420

ccaattgaat ttctagaaaa tgcatatgag aagtatggac ctgtatttag ttttaccatg      480

gtaggcaaga catttactta ccttctgggg agtgatgctg ctgcactgct ttttaatagt      540

aaaaatgaag acctgaatgc agaagatgtc tacagtcgcc tgacaacacc tgtgtttggg      600

aagggagttg catacgatgt gcctaatcca gttttcttgg agcagaagaa aatgttaaaa      660

agtggcctta acatagccca ctttaaacag catgtttcta taattgaaaa agaaacaaag      720

gaatactttg agagttgggg agaaagtgga gaaaaaaatg tgtttgaagc tctttctgag      780

ctcataattt taacagctag ccattgtttg catggaaagg aaatcagaag tcaactcaat      840

gaaaaggtag cacagctgta tgcagatttg gatggaggtt tcagccatgc agcctggctc      900

ttaccaggtt ggctgccttt gcctagtttc agacgcaggg acagagctca tcgggaaatc      960

aaggatattt tctataaggc aatccagaaa cgcagacagt ctcaagaaaa aattgatgac     1020

attctccaaa ctttactaga tgctacatac aaggatgggc gtcctttgac tgatgatgaa     1080

gtagcaggga tgcttattgg attactcttg gcagggcagc atacatcctc aactactagt     1140

gcttggatgg gcttcttttt ggccagagac aaaacacttc aaaaaaaatg ttatttagaa     1200

cagaaaacag tctgtggaga gaatctgcct cctttaactt atgaccagct caaggatcta     1260

aatttacttg atcgctgtat aaaagaaaca ttaagactta gacctcctat aatgatcatg     1320

atgagaatgg ccagaactcc tcagactgtg gcagggtata ccattcctcc aggacatcag     1380

gtgtgtgttt ctcccactgt caatcaaaga cttaaagact catgggtaga acgcctggac     1440

tttaatcctg atcgctactt acaggataac ccagcatcag gggaaaagtt tgcctatgtg     1500

ccatttggag ctgggcgtca tcgttgtatt ggggaaaatt ttgcctatgt tcaaattaag     1560

acaatttggt ccactatgct tcgtttatat gaatttgatc tcattgatgg atactttccc     1620

actgtgaatt atacaactat gattcacacc cctgaaaacc cagttatccg ttacaaacga     1680

agatcaaaat gaaaaaggtt gcaaggaacg aatatatgtg attatcactg taagccacaa     1740

aggcattcga agagaatgaa gtgtacaaaa caactcttgt agtttactgt ttttttaagt     1800

gtgtaattct aaaagccagt ttatgattta ggattttgtt aactgaatgg ttctatcaaa     1860

tataatagca tttgaaacat tttctaatag ttatgatact tatacatgtg ctttcaggaa     1920

gttccttggt gaaacaattg ttgagggggg atctaggtaa ttggcagatt ctaaataata     1980

taatttccag atagtaattt taagagtact catcgctctt gccaaataag ttcagggtat     2040

tcaaatcttg gactagtcct gcaaggtata aagaataaaa atcccagtga gatacttgga     2100

aaccacagtt tattattatt tatctgggca attattgtgt gtgtgaggat ggaagggtag     2160

ggaataatcg aacatctaaa gccttgaata agagaatact aattgttttg gtatgatgat     2220

actcagaaat ggagatatta taggaaaaag aaatcctttg gaattttaac taaaatcact     2280

gcatatggga aattaagaga tccaggacca tatttgataa gagttcctaa aaataatgta     2340

attattaatg ctaaagactg ctcatgtatc ttgatctaat tactaaataa ttacatattt     2400

atttacctga taaatatgta tctagttcta caaggtcaca tttatgtgga agtccaaagt     2460

caagtcctta ggggataatt ttgttttggc tcagttgttc cctgcttcct tttttttttt     2520

ttttttttga gatggagtct cgctctgttg cccaggctgg agtgcagtgg tgcgatctca     2580

gctcactgca tcctctgcct cccgggttca agcaattctc tgcctcagcc tcccaagtag     2640

ttgggattac aggcacctgc caccatgcct ggctaatttt ttgtattttt agtagagacg     2700

ggggtttcac tatgttggct aggctggtct tgaactcctg acctcgtgat ccacccgcct     2760

tggcctccca aagtgctggg attacaggca tgagccaccg cacctggcct tccctgcttc     2820

ctctctagaa tccaattagg gatgtttgtt actactcata ttgattaaaa cagttaacaa     2880

acttttttct ttttaaaatg tgagatcagt gaactctggt tttaagataa tctgaaacaa     2940

ggtccttggg agtaataaaa ttggtcacat tctgtaaagc acattctgtt taggaatcaa     3000

cttatctcaa attgtaactc ggggcctaac tatatgagat ggctgaaaaa ataccacatc     3060

gtctgttttc actaggtgat gccaaaatat tttgctttat gtatattaca gttcttttta     3120

aaacactgga agactcatgt taaactctaa ttgtgaaggc agaatctctg ctaatttttc     3180

agattaaaat tctctttgaa aaaataca                                        3208


<210>  1783
<211>  1808
<212>  DNA
<213>  homo sapiens

<400>  1783
agcctagtta cagattgcac tgcgtcagac tgttccacac ccagaagacg tcaggtgact       60

tcagtcctgc tgcagttgtg cagcagagga gactgcagac ttcggttgag gaaacgggta      120

tttcatgtct cagggagtag gtttgtgcag ttacagcttt tctgttggta tgcataatta      180

ataattggag ctgcaaagca gatcgtgaca agagatggac ggtcagaaga aaaattggaa      240

ggacaaggtt gttgacctcc tgtactggag agacattaag aagactggag tggtgtttgg      300

tgccagccta ttcctgctgc tttcattgac agtattcagc attgtgagcg taacagccta      360

cattgccttg gccctgctct ctgtgaccat cagctttagg atatacaagg gtgtgatcca      420

agctatccag aaatcagatg aaggccaccc attcagggca tatctggaat ctgaagttgc      480

tatatctgag gagttggttc agaagtacag taattctgct cttggtcatg tgaactgcac      540

gataaaggaa ctcaggcgcc tcttcttagt tgatgattta gttgattctc tgaagtttgc      600

agtgttgatg tgggtattta cctatgttgg tgccttgttt aatggtctga cactactgat      660

tttggctctc atttcactct tcagtgttcc tgttatttat gaacggcatc aggcacagat      720

agatcattat ctaggacttg caaataagaa tgttaaagat gctatggcta aaatccaagc      780

aaaaatccct ggattgaagc gcaaagctga atgaaaacgc ccaaaataat tagtaggagt      840

tcatctttaa aggggatatt catttgatta tacgggggag ggtcagggaa gaacgaacct      900

tgacgttgca gtgcagtttc acagatcgtt gttagatctt tatttttagc catgcactgt      960

tgtgaggaaa aattacctgt cttgactgcc atgtgttcat catcttaagt attgtaagct     1020

gctatgtatg gatttaaacc gtaatcatat ctttttccta tctatctgag gcactggtgg     1080

aataaaaaac ctgtatattt tactttgttg cagatagtct tgccgcatct tggcaagttg     1140

cagagatggt ggagctagaa aaaaaaaaaa aaaagccctt ttcagtttgt gcactgtgta     1200

tggtccgtgt agattgatgc agattttctg aaatgaaatg tttgtttaga cgagatcata     1260

ccggtaaagc aggaatgaca aagcttgctt ttctggtatg ttctaggtgt attgtgactt     1320

ttactgttat attaattgcc aatataagta aatatagatt atatatgtat agtgtttcac     1380

aaagcttaga cctttacctt ccagccaccc cacagtgctt gatatttcag agtcagtcat     1440

tggttataca tgtgtagttc caaagcacat aagctagaag aagaaatatt tctaggagca     1500

ctaccatctg ttttcaacat gaaatgccac acacatagaa ctccaacatc aatttcattg     1560

cacagactga ctgtagttaa ttttgtcaca gaatctatgg actgaatcta atgcttccaa     1620

aaatgttgtt tgtttgcaaa tatcaaacat tgttatgcaa gaaattatta attacaaaat     1680

gaagatttat accattgtgg tttaagctgt actgaactaa atctgtggaa tgcattgtga     1740

actgtaaaag caaagtatca ataaagctta tagacttaaa aaaaaaaaaa aaaaaaaaaa     1800

aaaaaaaa                                                              1808


<210>  1784
<211>  2141
<212>  DNA
<213>  homo sapiens

<400>  1784
gccgacgcgt gcagacgtcc ttctaatcct agtcttcgtt tggtccggtt gcactcttcc       60

tatagcccag agggcgagag ggcctgtggc ctgggggaag gaggacgagg ttctgcctgg      120

atcccagcag taggacgctg tgccatttgg gaacaaagga atagtctgcc tggaatccct      180

gcagatcttg gggccggagg ccagtccaac ccttggagca ggaagaaacg caaagttgtc      240

aagaaccaag tcgagctgcc tcagagccgg cccgcagtag ctgcagactc cgcccgcgac      300

gtgtgcgcgc ttctctgggc cagagcgagc ctgttttgtg ctcgggttaa gagatttgtc      360

ccagctatac catgggccgc actcgggaag ctggctgcgt ggccgctggt gtggttatcg      420

gggctggtgc ctgctactgt gtatacagac tggcttgggg aagagacgag aacgagaaaa      480

tctgggacga agacgaggag tctacggaca cctcagagat tggggttgag actgtgaaag      540

gagctaaaac taacgctggg gcagggtctg gggccaaact tcagggtgat tcagaggtca      600

agcctgaggt gagtttggga ctcgaggatt gtccgggtgt aaaagagaag gcccattcag      660

gatcccacag cggaggtggc ctagaggcca aggccaaggc ccttttcaac acgctgaagg      720

aacaggcaag tgcaaaggca ggcaaagggg ctagggtggg taccatctct gggaacagga      780

cccttgcacc gagtttaccc tgcccaggag gcaggggtgg aggctgccac cccaccagga      840

gtggatctag ggccgggggc agggcaagtg gaaaatccaa gggaaaggcc cgaagtaaga      900

gcaccagggc tccagctaca acatggcctg tccggagagg caagttcaac tttccttata      960

aaattgatga tattctgagt gctcccgacc tccaaaaggt cctcaacatc ctggagcgaa     1020

caaatgatcc ttttattcaa gaagtagcct tggtcactct gggtaacaat gcagcatatt     1080

catttaacca gaatgccata cgtgaattgg gtggtgtccc aattattgca aaactgataa     1140

aaacaaaaga ccccataatt agggaaaaga cttacaatgc ccttaataac ttgagtgtga     1200

acgcagaaaa tcagggcaag attaagacgt acatcagtca agtgtgtgat gacaccatgg     1260

tctgtcgctt ggactcagct gtgcagatgg ctgggctaag actgttaacc aacatgactg     1320

tgactaatca ttaccaacat ttgctttcct attcttttcc agactttttt gctttgttat     1380

tcctgggaaa tcacttcacc aagatacaga ttatgaaact aattataaac tttactgaaa     1440

atccagccat gacaagagag ctggtcagtt gtaaagtacc atcagaattg atttccctct     1500

ttaataaaga atgggataga gagattcttc ttaatatcct taccctattt gagaatataa     1560

atgacaacat aaaaaatgaa gggctcgcat catccaggaa agaattcagc agaagttcac     1620

tttttttctt attcaaagag tctggagttt gtgttaagaa aatcaaagca ctagcaaatc     1680

acaatgatct ggtggtgaaa gtaaaagtcc tgaaagtatt aaccaaactc taatttggag     1740

tctgtcccaa acaatattga gatatttgca gttggtacga tgtgatttgt aaattctttg     1800

tttttcattg tgcgtatatg gtaaagagat cttttcagct gctattttgg aataatgact     1860

atcatatatc ataacagtga ctgatgttgg ttgtaatggt tgggtttagg atgaaccatt     1920

ttaaggatgc caaatgaaat attagtattt gtacacagaa agaatttatt gatttgatct     1980

tattacctag attgagattt tttaatcttt cctctaccta aactgacaat gaattggtta     2040

tacatcatgc ataagctaca cttttatatt agtttatatt tgttattcta agacttgtgt     2100

ttcatcaata aagttgtgtt ttaagcagca gaaaaaaaaa a                         2141


<210>  1785
<211>  6031
<212>  DNA
<213>  homo sapiens

<400>  1785
cttttcccat cgtgtagtca agagtctgtg ccagacttga aggctttact ttgttagcca       60

tgtgtttatg aacccccagc gctttcccta gatcttttgg ctgataatct caaacatgga      120

ggatgcttct gaatcttcac gaggggttgc tccattaatt aataatgtag ttctcccagg      180

ctctccgctg tctcttcctg tatcagtgac aggctgtaaa agtcatcgag tagccaataa      240

aaaggtagaa gcgaggagtg aaaagctcct cccaacagct cttcctcctt cagagccgaa      300

agtagatcag aaacttccca ggagctccga gaggcgggga agtggcggtg ggacgcaatt      360

ccccgcgcgg agtcgggcag tggcagcggg agaagcggca gccaggggcg cggcggggcc      420

ggagagaggc ggtcccctgg gaggacgggg tctcccctcg ttgcctttgt agtggagaag      480

gtggacaagt ggcagtcggc gtgatcgcag ggaagcgggg ccggcgcggg cggccgaggg      540

tccaggcgag cccgcgggcg gacgggagat gccgctgcta caccgaaagc cgtttgtgag      600

acagaagccg cccgcggacc tgcggcccga cgaggaagtt ttctactgta aagtcaccaa      660

cgagatcttc cgccactacg atgacttttt tgaacgaacc attctgtgca acagccttgt      720

gtggagttgt gctgtgacgg gtagacctgg actgacgtat caggaagcac ttgagtcaga      780

aaaaaaagca agacagaatc ttcagagttt tccagaacca ctaattattc cagttttata      840

cttgaccagc cttacccatc gttcgcgctt acatgaaatt tgtgatgata tctttgcata      900

tgtcaaggat cgatattttg tcgaagaaac tgtggaagtc attaggaaca atggtgcaag      960

gttgcagtgt aggattttgg aagtcctccc tccatcacat caaaatggtt ttgctaatgg     1020

acatgttaac agtgtggatg gagaaactat tatcatcagt gatagtgatg attcagaaac     1080

acaaagctgt tcttttcaaa atgggaagaa aaaagatgca attgatccct tactattcaa     1140

gtataaagtg caacccacta aaaaagaatt acatgagtct gctattgtta aagcaacaca     1200

aatcagccgg agaaaacacc tattttctcg tgataaacta aagctttttc tgaagcaaca     1260

ctgtgaacca caagatggag tcattaaaat aaaggcatca tctctttcaa cgtataaaat     1320

agcagaacaa gatttttctt atttcttccc tgatgatcca cccacattta tcttcagtcc     1380

tgctaacaga cgaagaggga gacctcccaa acgaatacat attagtcaag aggacaatgt     1440

tgctaataaa cagactcttg caagttatag gagcaaagct actaaagaaa gagataaact     1500

tttgaaacaa gaagaaatga agtcactggc ttttgaaaag gctaaattaa aaagagaaaa     1560

agcagatgcc ctagaagcga agaaaaaaga aaaagaagat aaagagaaaa agagggaaga     1620

attgaaaaaa attgttgaag aagagagact aaagaaaaaa gaagaaaaag agaggcttaa     1680

agtagaaaga gaaaaggaaa gagagaagtt acgtgaagaa aagcgaaagt atgtggaata     1740

cttaaaacag tggagtaaac ctagagaaga tatggaatgt gatgacctta aggaacttcc     1800

agaaccaaca ccagtgaaaa ctagactacc tcctgaaatc tttggtgatg ctctgatggt     1860

tttggagttc cttaatgcat ttggggaact ttttgatctt caagatgagt ttcctgatgg     1920

agtaacccta gaagtattag aggaagctct tgtaggaaat gacagtgaag gcccactgtg     1980

tgaattgctt tttttcttcc tgactgcaat cttccaggca atagctgaag aagaagagga     2040

agtagccaaa gagcaactaa ctgatgctga caccaaagat ttaacagagg ctttggatga     2100

agatgcagac cccacaaaat ctgcactgtc tgcagttgca tctttggcag ctgcatggcc     2160

acagttacac cagggctgca gtttgaaaag tttggatctt gatagctgca ctctttcaga     2220

aatcctcaga ctgcacatct tagcttcagg tgctgatgta acatcagcaa atgcaaagta     2280

tagatatcaa aaacgaggag gatttgatgc tacagatgat gcttgtatgg agcttcgttt     2340

gagcaatccc agtctagtga agaaactgtc aagcacctca gtgtatgatt tgacaccagg     2400

agaaaaaatg aagatactcc atgctctctg tggaaagcta ctgaccctag tttcaactag     2460

ggattttatt gaagattatg ttgatatatt acgacaggca aagcaggagt tccgggaatt     2520

aaaagcagaa caacatcgaa aagagaggga agaagcagct gccagaattc gtaaaaggaa     2580

ggaagaaaaa cttaaggagc aagaacaaaa aatgaaagag aaacaagaaa aactgaaaga     2640

agatgagcaa agaaattcaa cggcagatat atctattggg gaggaagaaa gggaagattt     2700

tgatactagc attgagagca aagacacaga gcaaaaggaa ttagatcaag atatggtcac     2760

tgaagatgaa gatgacccag gatcacataa aagaggcaga agggggaaaa gaggacaaaa     2820

tggatttaaa gaatttacaa ggcaagaaca gatcaactgt gtaacaagag agcctcttac     2880

tgctgatgag gaagaagcat taaaacagga acaccaacga aaagagaaag agctcttaga     2940

aaaaatccaa agtgccatag cctgtaccaa tatctttccc ttgggtcgcg accgcatgta     3000

tagacgatac tggattttcc cttctattcc tggactcttt attgaagagg attattctgg     3060

tcttactgaa gacatgctgt tgcctagacc ttcatcattt cagaataatg tacagtctca     3120

agatcctcag gtatccacta aaactggaga gcctttgatg tctgaatcta cctccaacat     3180

tgaccaaggt ccacgtgacc attctgtgca gctgccaaaa ccagtgcata agccaaatcg     3240

gtggtgcttt tacagttctt gtgaacagct agaccagctt attgaagctc ttaattctag     3300

aggacataga gaaagtgcct taaaagaaac tttgttacaa gagaaaagca gaatatgtgc     3360

acagctagcc cgtttttctg aagagaaatt tcatttttca gacaaacctc agcctgatag     3420

caaaccaaca tatagtcggg gaagatcttc caatgcatat gatccatctc agatgtgtgc     3480

agaaaagcaa cttgaactaa ggctgagaga ttttctttta gatattgaag atagaatcta     3540

ccaaggaaca ttaggagcca tcaaggttac agatcgacat atctggagat cagcattaga     3600

aagtggacgg tatgagctgt taagtgagga aaacaaggaa aatgggataa ttaaaactgt     3660

gaatgaagac gtagaagaga tggaaattga tgaacaaaca aaggtcatag taaaagacag     3720

acttttgggg ataaaaacag aaactccaag tactgtatca acaaatgcaa gtacaccaca     3780

atcagtgagc agtgtggttc attatctggc aatggcactc tttcaaatag agcagggcat     3840

tgagcggcgt tttctgaaag ctccacttga tgccagtgac agtgggcgtt cttataaaac     3900

agttctggac cgttggagag agtctctcct ttcttctgct agtctatccc aagtttttct     3960

tcacctatcc accttggatc gtagcgtgat atggtctaaa tctatactga atgcgcgttg     4020

caagatatgt cgaaagaaag gcgatgctga aaacatggtt ctttgtgatg gctgtgatag     4080

gggtcatcat acctactgtg ttcgaccaaa gctcaagact gtgcctgaag gagactggtt     4140

ttgtccagaa tgtcgaccaa agcaacgttc tagaagactc tcctctagac agagaccatc     4200

cttggaaagt gatgaagatg tggaagacag tatgggaggt gaggatgatg aagttgatgg     4260

cgatgaagaa gaaggtcaaa gtgaggagga agagtatgag gtagaacaag atgaagatga     4320

ctctcaagaa gaggaagaag tcagcctacc caaacgagga agaccacaag ttagattgcc     4380

agttaaaaca agagggaaac ttagctcttc tttctcaagt cgtggccaac aacaagaacc     4440

tggaagatac ccttcaagga gtcagcagag cacacccaaa acaactgttt cttctaaaac     4500

tggtagaagc ctaagaaaga taaactctgc tcctcctaca gaaacaaaat ctttaagaat     4560

tgccagtcgt tctactcgcc acagtcatgg cccactgcaa gcagatgtat ttgtggaatt     4620

gcttagtcct cgtagaaaac gcagaggcag gaaaagtgct aataatacac cagaaaatag     4680

tcccaacttc cctaacttca gagtcattgc cacaaagtca agtgaacagt caagatctgt     4740

aaatattgct tcaaaacttt ctctccaaga gagtgaatcc aaaagaagat gcagaaaaag     4800

acaatctcca gagccatcgc ctgtgacact gggtcgaagg agttctggcc gacagggagg     4860

agttcatgaa ttgtctgctt ttgaacaact tgttgtagaa ttggtacgac atgatgacag     4920

ctggcctttt ttgaaacttg tttctaaaat ccaggtccca gactactatg acatcatcaa     4980

aaagcccatt gccttaaata taattcgtga aaaagtgaat aagtgtgaat ataaattagc     5040

atctgagttt attgatgaca ttgagttaat gttttcgaac tgctttgaat acaaccctcg     5100

taacacaagt gaagcaaaag ctggaactag gcttcaagca ttttttcata ttcaggctca     5160

aaagcttgga ctccacgtca cacccagtaa tgtggaccaa gttagcacac caccggctgc     5220

gaaaaagtca cgaatctgac tttgtccttc taaaggatat atttgaagaa aaacaaattg     5280

ttcatgaaaa tggaacatta aatcatgctg tataaagcaa taacaattga ttgaccacat     5340

gaaagtgtgg cctgcactat attctcaatt ttaatattaa gcactcagga gaatgtagga     5400

aagatatcct ttgctacagt tttgttcagt atctaataag tttgatagat gtattggata     5460

cagtactggt ttacagaggt ttttgtacat ttttgagatc attcatgtgt ccagagatct     5520

tggaaaatat tttttcaccc acgatttatt ttgttattga tgattttttt ttaaagtggt     5580

ggtattaagg gagagttatc tacatggatg agtcttccgc tatagcacag tttagaaaag     5640

gtgtttatgt cttaattaat tgtttgagta cattctttca acactacaca tgaatgaatc     5700

caatcttata accttgaagt gctgtaccag tgctggctgc aggtattaag tccaagttta     5760

ttaactagat atttatttag tattgagagt aatttgtgaa tttgttttgt atttataaaa     5820

tttatacctg aaaaatgttc cttaatgttt taaacctttt actgtgtttt tattcctcta     5880

acttccttaa tgatcaatca aaaaaagtaa caccctccct ttttcctgac agttctttca     5940

gctttacaga actgtattat aagtttctat gtataacttt ttaactgtac aaataaaata     6000

acattttttc aaataaaaaa aaaaaaaaaa a                                    6031


<210>  1786
<211>  8000
<212>  DNA
<213>  homo sapiens

<400>  1786
gagtagctcc agcggccacg ctgaggcgag ggtgacacac catgctcacg gcccctggag       60

accgtcgtgc tggcgagccg tgctccgtag ctccccggtc cgcctcggca gcggtcagag      120

tcgcctacag gagttgagcc gcccgcgcca gaaggttttg gcgaagctct tggagaggcg      180

tcgagcacag tagggcggcg ggggtgcgtt gagcgctcgg gggtcaggca gtcggccggg      240

atcgccgctg gggagcgttt ccgaggcgag gaggaggagg aggagatgct gctcctcttc      300

tccccctccc caggctcctt ctacagctcc ttcagcccac gcccgcagcc gcttgtggga      360

gaagtggtgg tggctctcgg cgcccgcggc ggctgccggc ggcccgcccc gacgccgcgt      420

ccctgcagcc ctcgcccggc gctccagtag caggacccgg tctcgggacc agccggtaat      480

atgcacgtgt cactagctga ggccctggag gttcggggtg gaccacttca ggaggaagaa      540

atatgggctg tattaaatca aagtgctgaa agtctccaag aattattcag aaaagtaagc      600

ctagctgatc ctgctgccct tggcttcatc atttctccat ggtctctgct gttgctgcca      660

tctggtagtg tgtcatttac agatgaaaat atttccaatc aggatcttcg agcattcact      720

gcaccagagg ttcttcaaaa tcagtcacta acttctctct cagatgttga aaagatccac      780

atttattctc ttggaatgac actgtattgg ggggctgatt atgaagtgcc tcagagccaa      840

cctattaagc ttggagatca tctcaacagc atactgcttg gaatgtgtga ggatgttatt      900

tacgctcgag tttctgttcg gactgtgctg gatgcttgca gtgcccacat taggaatagc      960

aattgtgcac cctcattttc ctacgtgaaa cacttggtaa aactggttct gggaaatctt     1020

tctgggacag atcagctttc ctgtaacagt gaacaaaagc ctgatcgaag ccaggctatt     1080

cgagatcgat tgcgaggaaa aggattacca acaggaagaa gctctacttc tgatgtacta     1140

gacatacaaa agcctccact ctctcatcag acctttctta acaaagggct tagtaaatct     1200

atgggatttc tgtccatcaa agatacacaa gatgagaatt atttcaagga cattttatca     1260

gataattctg gacgtgaaga ttctgaaaat acattctccc cttaccagtt caaaactagt     1320

ggcccagaaa aaaaacccat ccctggcatt gatgtgcttt ctaagaagaa gatctgggct     1380

tcatccatgg acttgctttg tacagctgac agagacttct cttcaggaga gactgccaca     1440

tatcgtcgtt gtcaccctga ggcagtaaca gtgcggactt caactactcc tagaaaaaag     1500

gaggcaagat actcagatgg aagtatagcc ttggatatct ttggccctca gaaaatggat     1560

ccaatatatc acactcgaga attgcccacc tcctcagcaa tatcaagtgc tttggaccga     1620

atccgagaga gacaaaagaa acttcaggtt ctgagggaag ccatgaatgt agaagaacca     1680

gttcgaagat acaaaactta tcatggtgat gtctttagta cctccagtga aagtccatct     1740

attatttcct ctgaatcaga tttcagacaa gtgagaagaa gtgaagcctc aaagaggttt     1800

gaatccagca gtggtctccc aggggtagat gaaaccttaa gtcaaggcca gtcacagaga     1860

ccgagcagac aatatgaaac accctttgaa ggcaacttaa ttaatcaaga gatcatgcta     1920

aaacggcaag aggaagaact gatgcagcta caagccaaaa tggcccttag acagtctcgg     1980

ttgagcctat atccaggaga cacaatcaaa gcgtccatgc ttgacatcac cagggatccg     2040

ttaagagaaa ttgccctaga aacagccatg actcaaagaa aactgaggaa tttctttggc     2100

cctgagtttg tgaaaatgac aattgaacca tttatatctt tggatttgcc acggtctatt     2160

cttactaaga aagggaagaa tgaggataac cgaaggaaag taaacataat gcttctgaac     2220

gggcaaagac tggaactgac ctgtgatacc aaaactatat gtaaagatgt gtttgatatg     2280

gttgtggcac atattggctt agtagagcat catttgtttg ctttagctac cctcaaagat     2340

aatgaatatt tctttgttga tcctgactta aaattaacca aagtggcccc agagggatgg     2400

aaagaagaac caaagaaaaa gaccaaagcc actgttaatt ttactttgtt tttcagaatt     2460

aaatttttta tggatgatgt tagtctaata caacatactc tgacgtgtca tcagtattac     2520

cttcagcttc gaaaagatat tttggaggaa aggatgcact gtgatgatga gacttcctta     2580

ttgctggcat ccttggctct ccaggctgag tatggagatt atcaaccaga ggttcatggt     2640

gtgtcttact ttagaatgga gcactatttg cccgccagag tgatggagaa acttgattta     2700

tcctatatca aagaagagtt acccaaattg cataatacct atgtgggagc ttctgaaaaa     2760

gagacagagt tagaattttt aaaggtctgc caaagactga cagaatatgg agttcatttt     2820

caccgagtgc accctgagaa gaagtcacaa acaggaatat tgcttggagt ctgttctaaa     2880

ggtgtccttg tgtttgaagt tcacaatgga gtgcgcacat tggtccttcg ctttccatgg     2940

agggaaacca agaaaatatc tttttctaaa aagaaaatca cattgcaaaa tacatcagat     3000

ggaataaaac atggcttcca gacagacaac agtaagatat gccagtacct gctgcacctc     3060

tgctcttacc agcataagtt ccagctacag atgagagcaa gacagagcaa ccaagatgcc     3120

caagatattg atgtgctaca caaaagatgg agcatagtat cttcaccaga aagggagatc     3180

accttagtga acctgaaaaa agatgcaaag tatggcttgg gatttcaaat tattggtggg     3240

gagaagatgg gaagactgga cctaggcata tttatcagtt cagttgcccc tggaggacca     3300

gctgacttgg atggatgctt gaagccagga gaccgtttga tatctgtgaa tagtgtgagt     3360

ctggagggag tcagccacca tgctgcaatt gaaattttgc aaaatgcacc tgaagatgtg     3420

acacttgtta tctctcagcc aaaagaaaag atatccaaag tgccttctac tcctgtgcat     3480

ctcaccaatg agatgaaaaa ctacatgaag aaatcttcct acatgcaaga cagtgctata     3540

gattcttctt ccaaggatca ccactggtca cgtggtaccc tgaggcacat ctcggagaac     3600

tcctttgggc catctggggg cctgcgggaa ggaagcctga gttctcaaga ttccaggact     3660

gagagtgcca gcttgtctca aagccaggtc aatggtttct ttgccagcca tttaggtgac     3720

caaacctggc aggaatcaca gcatggcagc ccttccccat ctgtaatatc caaagccacc     3780

gagaaagaga ctttcactga tagtaaccaa agcaaaacta aaaagccagg catttctgat     3840

gtaactgatt actcagaccg tggagattca gacatggatg aagccactta ctccagcagt     3900

caggatcatc aaacaccaaa acaggaatct tcctcttcag tgaatacatc caacaagatg     3960

aattttaaaa ctttttcttc atcacctcct aagcctggag atatctttga ggttgaactg     4020

gctaaaaatg ataacagctt ggggataagt gtcacgggag gtgtgaatac gagtgtcaga     4080

catggtggca tttatgtgaa agctgttatt ccccagggag cagcagagtc tgatggtaga     4140

attcacaaag gtgatcgcgt cctagctgtc aatggagtta gtctagaagg agccacccat     4200

aagcaagctg tggaaacact gagaaataca ggacaggtgg ttcatctgtt attagaaaag     4260

ggacaatctc caacatctaa agaacatgtc ccggtaaccc cacagtgtac cctttcagat     4320

cagaatgccc aaggtcaagg cccagaaaaa gtgaagaaaa caactcaggt caaagactac     4380

agctttgtca ctgaagaaaa tacatttgag gtaaaattat ttaaaaatag ctcaggtcta     4440

ggattcagtt tttctcgaga agataatctt ataccggagc aaattaatgc cagcatagta     4500

agggttaaaa agctctttcc tggacagcca gcagcagaaa gtggaaaaat tgatgtagga     4560

gatgttatct tgaaagtgaa tggagcctct ttgaaaggac tatctcagca ggaagtcata     4620

tctgctctca ggggaactgc tccagaagta ttcttgcttc tctgcagacc tccacctggt     4680

gtgctaccgg aaattgatac tgcgcttttg accccacttc agtctccagc acaagtactt     4740

ccaaacagca gtaaagactc ttctcagcca tcatgtgtgg agcaaagcac cagctcagat     4800

gaaaatgaaa tgtcagacaa aagcaaaaaa cagtgcaagt ccccatccag aagagacagt     4860

tacagtgaca gcagtgggag tggagaagat gacttagtga cagctccagc aaacatatca     4920

aattcgacct ggagttcagc tttgcatcag actctaagca acatggtatc acaggcacag     4980

agtcatcatg aagcacccaa gagtcaagaa gataccattt gtaccatgtt ttactatcct     5040

cagaaaattc ccaataaacc agagtttgag gacagtaatc cttcccctct accaccggat     5100

atggctcctg ggcagagtta tcaaccccaa tcagaatctg cttcctctag ttcgatggat     5160

aagtatcata tacatcacat ttctgaacca actagacaag aaaactggac acctttgaaa     5220

aatgacttgg aaaatcacct tgaagacttt gaactggaag tagaactcct cattacccta     5280

attaaatcag aaaaaggaag cctgggtttt acagtaacca aaggcaatca gagaattggt     5340

tgttatgttc atgatgtcat acaggatcca gccaaaagtg atggaaggct aaaacctggg     5400

gaccggctca taaaggttaa tgatacagat gttactaata tgactcatac agatgcagtt     5460

aatctgctcc gggctgcatc caaaacagtc agattagtta ttggacgagt tctagaatta     5520

cccagaatac caatgttgcc tcatttgcta ccggacataa cactaacgtg caacaaagag     5580

gagttgggtt tttccttatg tggaggtcat gacagccttt atcaagtggt atatattagt     5640

gatattaatc caaggtccgt cgcagccatt gagggtaatc tccagctatt agatgtcatc     5700

cattatgtga acggagtcag cacacaagga atgaccttgg aggaagttaa cagagcatta     5760

gacatgtcac ttccttcatt ggtattgaaa gcaacaagaa atgatcttcc agtggtcccc     5820

agctcaaaga ggtctgctgt ttcagctcca aagtcaacca aaggcaatgg ttcctacagt     5880

gtggggtctt gcagccagcc tgccctcact cctaatgatt cattctccac ggttgctggg     5940

gaagaaataa atgaaatatc gtaccccaaa ggaaaatgtt ctacttatca gataaaggga     6000

tcaccaaact tgactctgcc caaagaatct tatatacaag aagatgacat ttatgatgat     6060

tcccaagaag ctgaagttat ccagtctctg ctggatgttg tggatgagga agcccagaat     6120

cttttaaacg aaaataatgc agcaggatac tcctgtggtc caggtacatt aaagatgaat     6180

gggaagttat cagaagagag aacagaagat acagactgcg atggttcacc tttacctgag     6240

tattttactg aggccaccaa aatgaatggc tgtgaagaat attgtgaaga aaaagtaaaa     6300

agtgaaagct taattcagaa gccacaagaa aagaagactg atgatgatga aataacatgg     6360

ggaaatgatg agttgccaat agagagaaca aaccatgaag attctgataa agatcattcc     6420

tttctgacaa acgatgagct cgctgtactc cctgtcgtca aagtgcttcc ctctggtaaa     6480

tacacgggtg ccaacttaaa atcagtcatt cgagtcctgc ggggtttgct agatcaagga     6540

attccttcta aggagctgga gaatcttcaa gaattaaaac ctttggatca gtgtctaatt     6600

gggcaaacta aggaaaacag aaggaagaac agatataaaa atatacttcc ctatgatgct     6660

acaagagtgc ctcttggaga tgaaggtggc tatatcaatg ccagcttcat taagatacca     6720

gttgggaaag aagagttcgt ttacattgcc tgccaaggac cactgcctac aactgttgga     6780

gacttctggc agatgatttg ggagcaaaaa tccacagtga tagccatgat gactcaagaa     6840

gtagaaggag aaaaaatcaa atgccagcgc tattggccca acatcctagg caaaacaaca     6900

atggtcagca acagacttcg actggctctt gtgagaatgc agcagctgaa gggctttgtg     6960

gtgagggcaa tgacccttga agatattcag accagagagg tgcgccatat ttctcatctg     7020

aatttcactg cctggccaga ccatgataca ccttctcaac cagatgatct gcttactttt     7080

atctcctaca tgagacacat ccacagatca ggcccaatca ttacgcactg cagtgctggc     7140

attggacgtt cagggaccct gatttgcata gatgtggttc tgggattaat cagtcaggat     7200

cttgattttg acatctctga tttggtgcgc tgcatgagac tacaaagaca cggaatggtt     7260

cagacagagg atcaatatat tttctgctat caagtcatcc tttatgtcct gacacgtctt     7320

caagcagaag aagagcaaaa acagcagcct cagcttctga agtgacatga aaagagcctc     7380

tggatgcatt tccatttctc tccttaacct ccagcagact cctgctctct atccaaaata     7440

aagatcacag agcagcaagt tcatacaaca tgcatgttct cctctatctt agaggggtat     7500

tcttcttgaa aataaaaaat attgaaatgc tgtattttta cagctacttt aacctatgat     7560

aattatttac aaaattttaa cactaaccaa acaatgcaga tcttagggat gattaaaggc     7620

agcatttgat gatagcagac attgttacaa ggacatggtg agtctatttt taatgcacca     7680

atcttgttta tagcaaaaat gttttccaat attttaataa agtagttatt ttatagggga     7740

tacttgaaac cagtatttaa gctttaaatg acagtaatat tggcatagaa aaaagtagca     7800

aatgtttact gtatcaattt ctaatgttta ctatatagaa tttcctgtaa tatatttata     7860

tactttttca tgaaaatgga gttatcagtt atctgtttgt tactgcatca tctgtttgta     7920

atcattatct cactttgtaa ataaaaacac accttaaaac atgaacaagc caaaactgtg     7980

tgcagacaaa aaaaaaaaaa                                                 8000


<210>  1787
<211>  3529
<212>  DNA
<213>  homo sapiens

<400>  1787
taagaaacga cacacagatt aggcagtgct actcttctta aatctctcat ttgtttccta       60

ggttccctgg ttgtgaaaat acatgagata aatcatgaag gccactatca tcctccttct      120

gcttgcacaa gtttcctggg ctggaccgtt tcaacagaga ggcttatttg actttatgct      180

agaagatgag gcttctggga taggcccaga agttcctgat gaccgcgact tcgagccctc      240

cctaggccca gtgtgcccct tccgctgtca atgccatctt cgagtggtcc agtgttctga      300

tttgggtctt cctccttccc ttacggaatt acatcttgat ggcaacaaaa tcagcagagt      360

tgatgcagct agcctgaaag gactgaataa tttggctaag ttgggattga gtttcaacag      420

catctctgct gttgacaatg gctctctggc caacacgcct catctgaggg agcttcactt      480

ggacaacaac aagcttacca gagtacctgg tgggctggca gagcataagt acatccaggt      540

tgtctacctt cataacaaca atatctctgt agttggatca agtgacttct gcccacctgg      600

acacaacacc aaaaaggctt cttattcggg tgtgagtctt ttcagcaacc cggtccagta      660

ctgggagata cagccatcca ccttcagatg tgtctacgtg cgctctgcca ttcaactcgg      720

aaactataag taattctcaa gaaagccctc atttttataa cctggcaaaa tcttgttaat      780

gtcattgcta aaaaataaat aaaagctaga tactggaaac ctaactgcaa tgtggatgtt      840

ttacccacat gacttattat gcataaagcc aaatttccag tttaagtaat tgcctacaat      900

aaaaagaaat tttgcctgcc attttcagaa tcatcttttg aagctttctg ttgatgttaa      960

ctgagctact agagatattc ttatttcact aaatgtaaaa tttggagtaa atatatatgt     1020

caatatttag taaagctttt cttttttaat ttccaggaaa aaataaaaag agtatgagtc     1080

ttctgtaatt cattgagcag ttagctcatt tgagataaag tcaaatgcca aacactagct     1140

ctgtattaat ccccatcatt actggtaaag cctcatttga atgtgtgaat tcaatacagg     1200

ctatgtaaaa tttttactaa tgtcattatt ttgaaaaaat aaatttaaaa atacattcaa     1260

aattactatt gtatacaagc ttaattgtta atattcccta aacacaattt tatgaaggga     1320

gaagacattg gtttgttgac aataacagta catcttttca agttctcagc tatttcttct     1380

acctctccct atcttacatt tgagtatggt aacttatgtc atctatgttg aatgtaagct     1440

tataaagcac aaagcataca tttcctgact ggtctagaga actgatgttt caatttaccc     1500

ctctgctaaa taaatattaa aactatcatg tgacttcatg taatcaggct gaacatttct     1560

acaattacta gatgtattag acgtaagtat tttctttagt taaaccaccc atgttagaaa     1620

tgttttctgt agaatttata aacaactatc aatgcagaca atttaataag cctggggatg     1680

atttacttac agtaaacatt tatcaaattg tacatttgtg ctatcaacaa ttaataagca     1740

aatatgtgaa aatagtttct gtcttctatg aagttagata tttgatggtt aaaaccccta     1800

taaatcatag tttcatatgg gaaaaaataa ttgaaataca gtgtaaattt aaataattta     1860

ttaagtatag caaataattg aaatatggtg gactaaattt tgtcatagaa atatgtgcaa     1920

gttatagtag tggctcacat gagaggtaat caattctgct aatagtagca gaatgagtgc     1980

agtggaacat gaaaaacttg aggagataac agttgaggtg ggtttccata gatgcataat     2040

agttcaagag caagatttgg tggggaggca ctattcaaga cagggactaa gttcaaaatc     2100

caagacgtat gctgggacac acctctgaca ggttggcata aaggaggctt aatcaaacta     2160

tttttcttct tctgaaacag aagcaataat tttcatttac atttgacata tcccgaggta     2220

atattaacat tagggaaagt tactcttttc catctttcca cattcttgca ggaccataaa     2280

atctgaattt tccagtattt ttaataagag ggaagaaacc tctctttttc ttctcttttt     2340

catctcccaa gagatcctcc tctcatgact acagttgaat aggtggtttc tattggaaga     2400

cattcaggaa ttcaaggtgc atgtccataa atggactttt tttgttgttg ttcagagctg     2460

gaccttgaat gatgcatcct tctctctgtt gtaaccatga ataatgcacc cttcatgcta     2520

tagcctttaa cgattcaccc ttcttattgt aaccttgaat gattcaccct ttatggtgta     2580

gccttgagtg acgcaccctt catgttgtag ccttcaatga tgcacactcc atgttatagc     2640

cttgaatgat atacccttta tgctgcagcc tttctcttat ggggaaaagc ctgcagatat     2700

cctgctgctt aactgacaag tgtggtgaga aataagtaga aatctaaaga ggggaagacc     2760

attttggaca cttatctgca aggcagatcc aacacacttt tccagtagtc aagctacttc     2820

taattttgtt cagtatcaaa atgagaaaca ggcctgattc tccagcactc ttgtcaacac     2880

aacttccccc catatttata tatatacaca cacatatata tctttatata tatacacaca     2940

tatatatctt tatatatata tatttatata tatatctttt tgcatatata catatatatg     3000

tatctttatt tcctttgaaa taaagataaa tatagctgat ttctttggct tcgacactta     3060

ctatttgcat gactaaggga agctagttaa cctttctgtg actcatttcc ttgtccataa     3120

aatgggaata ttaattgtac atgtcttatg gattggtgtg tgaattcagt tagcgagtgt     3180

agaatataac ttatagatca aagtagagta aatggaaagg gctcaactat ggtgttgcta     3240

ctgccattgt tattacaggc acacagttcg agctataatc atttcaaggg aaattcttat     3300

gtgtcagttc tggatcgagg tctgagattc tgcatttcaa acaaacttcc aggaatgctg     3360

ctgcttcttg gtccacactt ggagaaataa gtcagcagag agtcctctcg tttcctattg     3420

taccatgtct gtcttttgtc tcctgcttat tggcctctgt aaggaactca cagctgctat     3480

aataaagtac caaaaactgg gtggcttaaa acaaaaaaaa aaaaaaaaa                 3529


<210>  1788
<211>  3313
<212>  DNA
<213>  homo sapiens

<400>  1788
gttccattcc cgggggattg gagtagcgtt ggagtcaccg acgccatccc ctcccgcctc       60

tggcgtgcat ggagcatgcg cttccttcct cacttcctct gcaggaggga gcgagagtaa      120

agctacgccc tggcgcgcag tctccgcgtc acaggaactt cagcacccac agggcggaca      180

gcgctcccct ctacctggag acttgactcc cgcgcgcccc aaccctgctt atcccttgac      240

cgtcgagtgt cagagatcct gcagccgccc agtcccggcc cctctcccgc cccacaccca      300

ccctcctggc tcttcctgtt tttactcctc cttttcattc ataacaaaag ctacagctcc      360

aggagcccag cgccgggctg tgacccaagc cgagcgtgga agaatggggt tcctcgggac      420

cggcacttgg attctggtgt tagtgctccc gattcaagct ttccccaaac ctggaggaag      480

ccaagattgc tgaagcagaa gaagacaaga ttaaaaaaac atatcctcca gaaaacaagc      540

caggtcagag caactattct tttgttgata acttgaacct gctaaaggca ataacagaaa      600

aggaaaaaat tgagaaagaa agacaatcta taagaagctc cccacttgat aataagttga      660

atgtggaaga tgttgattca accaagaatc gaaaactgat cgatgattat gactctacta      720

agagtggatt ggatcataaa tttcaagatg atccagatgg tcttcatcaa ctagacggga      780

ctcctttaac cgctgaagac attgtccata aaatcgctgc caggatttat gaagaaaatg      840

acagagccgt gtttgacaag attgtttcta aactacttaa tctcggcctt atcacagaaa      900

gccaagcaca tacactggaa gatgaagtag cagaggtttt acaaaaatta atctcaaagg      960

aagccaacaa ttatgaggag gatcccaata agcccacaag ctggactgag aatcaggctg     1020

gaaaaatacc agagaaagtg actccaatgg cagcaattca agatggtctt gctaagggag     1080

aaaacgatga aacagtatct aacacattaa ccttgacaaa tggcttggaa aggagaacta     1140

aaacctacag tgaagacaac tttgaggaac tccaatattt cccaaatttc tatgcgctac     1200

tgaaaagtat tgattcagaa aaagaagcaa aagagaaaga aacactgatt actatcatga     1260

aaacactgat tgactttgtg aagatgatgg tgaaatatgg aacaatatct ccagaagaag     1320

gtgtttccta ccttgaaaac ttggatgaaa tgattgctct tcagaccaaa aacaagctag     1380

aaaaaaatgc tactgacaat ataagcaagc ttttcccagc accatcagag aagagtcatg     1440

aagaaacaga cagtaccaag gaagaagcag ctaagatgga aaaggaatat ggaagcttga     1500

aggattccac aaaagatgat aactccaacc caggaggaaa gacagatgaa cccaaaggaa     1560

aaacagaagc ctatttggaa gccatcagaa aaaatattga atggttgaag aaacatgaca     1620

aaaagggaaa taaagaagat tatgaccttt caaagatgag agacttcatc aataaacaag     1680

ctgatgctta tgtggagaaa ggcatccttg acaaggaaga agccgaggcc atcaagcgca     1740

tttatagcag cctgtaaaaa tggcaaaaga tccaggagtc tttcaactgt ttcagaaaac     1800

ataatatagc ttaaaacact tctaattctg tgattaaaat tttttgaccc aagggttatt     1860

agaaagtgct gaatttacag tagttaacct tttacaagtg gttaaaacat agctttcttc     1920

ccgtaaaaac tatctgaaag taaagttgta tgtaagctga gattttgtat acagaatcct     1980

tatttcctca tagacttata ttttataatc agaatatgtt gctttgaaaa agcctctaat     2040

ggactgacct taaaactcat ccttcttcca ctgtctcatc cacataagca ctccccgaag     2100

aattaagggg gttctgtttt caaggcatgc caagtactaa agcaccttgc agagcgtgtc     2160

tattacaaga tgtcatttcc accagcagtt cccttagggg agctgaaata aattcacatt     2220

ttctcaaagt ctcatagctt tggaggagcc atctgctttt ttggctgctc tttttagctg     2280

gctttttatt aggctcagtg acataaaaag gatccaggta aatgggtata ggatttgctg     2340

gatttactaa caatttcccc ctgttcttaa cacttcctat tagtgacttt tcagacattg     2400

agtttactta taaagagaga tatttatgta ctctctaaga agacaaatga ggtcataaac     2460

actgcataaa gcaaggcaaa aatgtatgcc acatctcagt tatctaaact agattagatc     2520

caagccaagt tttctcaaca gagagcaaag ggccaggcag taaggtagaa atagagataa     2580

aaatcattcc ttccttgtga tccaaagctg gtcgagcagc tttcctggag gaaaaggtta     2640

atgaacttca ggtccctgca actcagcccc caccacaaac acagccctgg aaacatacag     2700

tggcgcaagg tcctcttgaa atgttaatgg ttaatgttcc caaaccagag aatgctttga     2760

aaatgtatca ttcagtgtaa attaattaca tacatatttt tctatatatt tgtttcaaac     2820

tgtaaaaata acataatatg taatttgtgt attagtgaga ggtgaagcca gctggacttc     2880

ctgggtcgag tggggccttg gagaactttt ctgtcttaca agaggattgt aaaatgcacc     2940

catcagtgct ctgtaaaaca caccaatcag cgctctgtag ctagcaatag gtttgtaaaa     3000

tgcacccatc agcactctgt aaaacgcacc aatcagcact ctgtaaaatg caccaatcag     3060

caggattcta aaagtagaca atcacaggga ggattgaaaa aaagggcact ctgatagggc     3120

aaaaacggaa catgggaggg gacaaataag ggaataaaat ctggccaccc cagccagcag     3180

cagcaacctg ttcaggtcgc ctgccgctgt ggaagctttg tccttttgct cttcataata     3240

aaccttgcta ctgttcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaa                                                        3313


<210>  1789
<211>  5905
<212>  DNA
<213>  homo sapiens

<400>  1789
agtggctgcc cgggccgagg aggggcgcgc tgactgctca ccgcgagtca ggaggggccg       60

gcgggctcac ggagggagac agggtgggcg ggggcaaagg ctaggcgcta gggcggcggc      120

gccagcgtag agcggcggtt tggaggaaag atgagacgat tccagcaaga ttatggaaga      180

gcatagctac atacaaaagg agctagattt acaaaatggt agcttagagg aagactctgt      240

ggtgcattct gttgagaacg attcccaaaa catgatggag agcctcagcc caaagaaata      300

ctcttccagt ctgagattta aagccaatgg agactattct ggctcctatt taaccctctc      360

acaacctgtg cctgcaaaga gaagcccttc tcctttggga accagtgtca gaagcagccc      420

ctccttagcc aaaatccagg gaagcaagca gttctcttat gatggaactg acaaaaatat      480

tcctatgaaa cctccaactc ctttactcaa cactacatcc tccctcagtg gatatccact      540

tggaagagca gactttgatc attatactgg ccgggacagt gaaagggcct tgaggctctc      600

agagaagcct ccctattcca aatatagctc aaggcataaa tcgcatgaca atgtctactc      660

tcttggaggg ctggaaggtc ggaaggcatc tggctcgctc ctggccatgt ggaatggaag      720

ttccctgagt gatgctggcc cgcctcctat cagcagatcg ggagccgcaa gcatgccttc      780

aagcccaaag caagccagga aaatgagcat tcaggacagc ctggcgcttc aacccaagtt      840

aactagacac aaggagcttg catctgaaaa catcaatttg agaactagga agtactccag      900

cagcagcctg agtcacatgg gagcctacag ccgatcactt cccaggttgt acagagccac      960

agagaaccag ctgacacctc tcagcttgcc tccaagaaac tctctgggca attccaaacg     1020

aacaaaactt ggggaaaagg atctacctca tagcgtaata gacaatgaca attaccttaa     1080

tttttcttct ttgagctcag gggctttacc ctataaaacc tctgcttctg aaggcaatcc     1140

ttatgtaagt tctaccctca gtgtccctgc cagtccacga gtggctcgga agatgcttct     1200

ggcctccacc tcctcctgtg cctctgatga ctttgatcag gcttcatatg tggggacaaa     1260

cccgagtcat tcacttcttg ctggagagtc agacagagtt tttgcgacca ggaggaactt     1320

ctcttgtgga tctgtggaat ttgatgaggc agatttggaa agcctcagac aggcctcagg     1380

aaccccccag cctgcccttc gggaacggaa aagcagtatt agctccattt caggacgtga     1440

tgacctgatg gattatcacc ggcggcagag ggaggaaaga ctcagggagc aggaaatgga     1500

gcgattggag agacagcgtc tggagaccat cctcagtctc tgtgctgaat acacaaagcc     1560

tgacagtcgc ttatctactg ggaccaccgt ggaagatgtg cagaaaatca acaaggagct     1620

tgagaagctg cagctctctg atgaggagtc tgtgtttgag gaagccctca tgagccctga     1680

cacaagatac aggtgccacc ggaaagactc cctccctgat gcagacttgg caagctgtgg     1740

gagtctcagt cagagcagtg ccagcttctt tacccccagg agcaccagga atgatgaact     1800

actcagtgac ctcacccgga ctcctccacc accatcctcc acctttccga aagcttccag     1860

cgagtcctct tatctaagta tcctaccaaa gaccccagag ggtataagtg aagaacagag     1920

atctcaggag ttggctgcaa tggaagaaac ccggatagtc attctgaaca acctcgagga     1980

acttaagcaa aaaatcaaag acataaatga tcagatggat gagtctttca gagagttgga     2040

tatggaatgt gctcttttgg atggagaaca gaaatctgaa acaactgaac ttatgaagga     2100

gaaggagatt ttggatcatc taaaccggaa aatagctgaa ctggaaaaga acattgttgg     2160

tgaaaagacc aaggagaagg taaagcttga tgctgaaagg gaaaaactag agaggcttca     2220

ggagctttac tccgagcaga agacccagct ggacaattgt cctgagtcca tgagggaaca     2280

gttacaacaa caactgaaga gggatgctga cctgttggat gttgaaagca aacactttga     2340

agacctggag ttccagcagc ttgaacatga gagccgtcta gatgaagaaa aggagaactt     2400

gactcaacag ctcctgcgtg aagttgctga atatcaacgg aacatcgttt ctagaaagga     2460

aaaaatttct gcattgaaaa agcaagccaa tcacattgtt cagcaggctc agagagagca     2520

agatcatttt gtgaaagaaa agaataattt aataatgatg ttgcaaagag aaaaggagaa     2580

tctttgtaat ttggaaaaga aatactccag cctctctggg gggaaagggt ttcccgttaa     2640

ccccaatact ttaaaagagg gctatatcag tgtaaatgag attaatgagc cgtgtggcaa     2700

ttccacgaat ctatcccctt ccactcagtt tcctgctgat gctgatgctg ttgccactga     2760

gcctgccaca gctgtgctgg cgagccagcc acagagtaaa gagcacttta gaagtctgga     2820

agaaaggaaa aaacagcata aagaaggcct ctatctgagt gatactttgc ctcgaaagaa     2880

aaccacatct tccatctccc cacatttcag cagtgctact atggggagaa gcatcacccc     2940

aaaggcccat ctgcccctag gacagagtaa cagctgtgga agtgtgctcc ctccctcact     3000

ggcagccatg gccaaagact cagaatctcg gaggatgctc agaggttata atcaccaaca     3060

gatgagtgaa ggacacaggc agaaatctga attttataac cgcacagcat ctgaatcaaa     3120

tgtctacttg aatagtttcc attatccaga tcacagctac aaggaccagg cctttgatac     3180

tctgagcctc gatagctctg atagcatgga gaccagcatc tctgcttgct caccagacaa     3240

catctctagt gccagcactt caaatattgc tagaatagaa gaaatggaga gacttttgaa     3300

gcaggctcat gcagaaaaga cgcggctgct cgaatccagg gaacgggaaa tggaagccaa     3360

aaaacgagcc ctggaagaag aaaaacgacg ccgggaaatc ctggaaaaac gattacagga     3420

agaaactagc cagaggcaga agttaataga aaaggaagta aaaataaggg agagacaaag     3480

ggcacaggct cgtcctttga cacgctacct gcctgtccgg aaggaagact ttgatttgcg     3540

gagccatgta gagactgctg gccacaatat tgacacctgt taccatgtat caatcacaga     3600

gaagacctgc cgaggattcc tcatcaaaat gggtgggaaa attaaaacgt ggaaaaaacg     3660

ttggtttgtt tttgatcgga acaagcgaac attctcttat tatgcagaca agcatgaaac     3720

taaattgaaa ggagtaatat actttcaagc cattgaagaa gtctattatg atcacctcaa     3780

gaatgctaat aagagtccta atccgttact cacctttagc gtcaagactc atgacagaat     3840

ctattatatg gtagccccat cgccagaagc catgcggatc tggatggatg ttatagttac     3900

gggggcagaa ggttacactc acttcttgtt gtagtgaact gaggcaacag tccacttcag     3960

ggcagacggc aataatctct tacaagaatg aagccatatt caaccccaga tgagaaaacc     4020

caacagatcc atcccttgag ctgtaaacac tcagaactcc tttcatatca agacaagtta     4080

tttgtaaaaa ataaagaagg ggttttaata caaaccttca taataaatag caaaataatt     4140

gaagcttcca tgagaaagaa aacactattt tgataaattg gatcacttat aggaacattt     4200

ctaataaact gtttttaatc agttgtcgga tttggtgaaa taaactaaac aggttacaga     4260

atatctgtat gtacttggaa atacagaata actttatcac ccaaatcact ggcattgaca     4320

ttattggtaa tcaactggct ttttttaaaa aaggtagcat tttgttgaca gttattttgt     4380

aaacataagc aaataagggc ttggagggaa atacatttta ggaggagttt tgccttaatt     4440

ttttaagtac tgcaccaaaa ccaaagagct gacctgactt ctgtggaaca gtagtaactg     4500

caagtgatga actgcatttc gtattgttct gtatatttca aaatggtatt ttgatgccat     4560

caaatgccca ggaaattgac tttgcagtgt caccactggt gtaagctact atatatgtat     4620

atatatatgt agtaaaccac tttttgtaaa agaagaaaga gcaaaaagct gtgtgtttta     4680

gaaaaaaaag ccaggttacg caacaggcat tctgtcatgt tgaacaattt taaataaaga     4740

gaatatctgg tgttaggagc ttgttttgct gaagatttct ccattcctgg tgctgagaat     4800

aaaggcaacc agtagccaat gtcctttaga ttgtctgatt tctttttgtt gtggagcaca     4860

cctgctaact gctccctcaa cataactatg aaatcatagc tctgttttca ccaaagaaca     4920

gaccaattaa catacttatt tgcagaagtg gtgtagttct ataaaacggc aaatgaagtt     4980

caacttaata ttctctataa tgtattattt tattttattt tttacaatta gccttttttt     5040

tagttaattt ttgtcaaatg aaacgacttc aggcaagtct cttttataat ggtttttcaa     5100

gtgccattta ttctagttta tcatgttttg catgtttgaa agtatgaatg tgctctttcc     5160

taaaacatgg caaatgaata gatgtagaga ataacaatat tacttacaag atgaaatgat     5220

tagattagaa gtgtcccttt attaaacttt gtcagcctga ctgggtacaa ttcttttgtt     5280

aatttgcagt gtggtttgta tacacgtata cgtgttatca ataataagat tttgcaactg     5340

gatgacacaa gattttactt gaacagtgaa ggacaaaaat catgattgtg gaagatattt     5400

ttaaaatctg attttgcagc gatcactttt aaaccctgta gtgatgtaag actaaaatat     5460

aattgctaag attttgttgg ttaatgtaaa gatatgactt ttctgcactg tactctcttc     5520

ataggattgt aaaggtgttc taatccaatt gcatgatgta gtaagcctct taaatatgtg     5580

tgttaaatat attgagtttg gattaaaatg ttgacatgat ttcacatttg aaaataaact     5640

catctcttat tttgaagtta cctatctgta gtatgatgga ggatgaatta atcgcaaatg     5700

acagttgtag aaactatgta aagtttgttg tgtgctaaca ttatgatttg tagtgtataa     5760

actgaagtat tccaatagaa gtatctctgg ttacatccta ttgcttacaa aatgaaatga     5820

accctgaaaa actctgacat catattgttg tctgtttaca cagatacatt tattgctggg     5880

gattgcaaaa aaaaaaaaaa aaaaa                                           5905


<210>  1790
<211>  11492
<212>  DNA
<213>  homo sapiens

<400>  1790
agcggcggcc acgtagcgct gcggcggcag cggcagcggc cgaggccggg tctgaggagc       60

ggccctgagg acagacgttg ggcagggggg gaggggctgg cccagccggc ggttgtgact      120

cgagcgccgc ggctgcaggc ccccgccgca gggatggacc gccgaggcgg cggccggggc      180

ggcggaggcg gaggcggccg gcccggataa gatgctccca agtcccttgc agctctcttc      240

agaagaaaaa tcactagtgc tctgctcttg ccataatacc aaaccttttt gactcatgct      300

ttggtgctgc aacactggaa gaattgcaca cagtttccag gaatatcttt ttttcatttg      360

agtgattctt tgtggatgag aaaagatttg agtcttaata attaccttgt tttaaagcta      420

tttctttata gtctgaactg tttaataaat tgggccactt accaatgagc cacacagcca      480

gttcttgtca ggagctggtt gaaaactgtg ctgtgcatgt agcaggaatg gcacaagaag      540

atagccgtcg tggtcaagtg ccatcttcct tttatcatgg tgccaaccaa gaacttgacc      600

tgtccaccaa agtgtacaaa agggaatcag gaagtcctta ttctgtgtta gtggacacca      660

agatgagcaa accgcatctc catgaaacag aagaacagcc atatttcagg gagacaagag      720

cagtgtctga cgtgcatgct gttaaggaag accgggagaa ttctgatgac acagaggagg      780

aagaggaaga agtctcttac aaaagggagc agatcatagt ggaggtaaac cttaataatc      840

aaacattaaa tgtatctaaa ggggaaaagg gtgtctcttc tcagtccaaa gagactcctg      900

ttcttaagac aagcagtgag gaggaagagg aagagagtga ggaagaggcc acagatgaca      960

gcaatgacta tggagagaat gaaaagcaga agaaaaagga gaagatagta gagaaagtca     1020

gcgttacaca aaggagaacc aggagagctg cctctgttgc cgcagctacc acttccccta     1080

ctcccagaac tacaagaggt cgtaggaaga gtgtagagcc acctaagcgt aagaagcggg     1140

ccacaaagga gcccaaagca ccagtccaga aagctaagtg tgaagagaaa gagactctga     1200

cctgtgagaa gtgccccagg gtatttaaca ctcgctggta cctggagaag cacatgaacg     1260

ttactcatag gcgcatgcag atttgtgata aatgtggcaa gaagtttgtc ctggaaagtg     1320

agctgtccct tcaccagcaa acagactgtg aaaaaaacat tcagtgtgtt tcctgtaaca     1380

aatcgttcaa gaaactctgg tcccttcatg aacatatcaa gatcgtccat ggatatgcag     1440

aaaagaaatt ttcctgtgaa atttgtgaga agaaattcta taccatggct catgtgcgga     1500

aacacatggt tgcacacaca aaagacatgc catttacatg cgaaacctgt ggaaaatcat     1560

tcaaacgcag tatgtcactc aaggtgcact ccttgcagca ttctggagag aagcccttta     1620

gatgcgagaa ctgtgacgaa aggtttcagt acaagtacca gctacgctcc cacatgagca     1680

ttcatattgg gcacaaacag ttcatgtgcc agtggtgtgg caaggatttc aacatgaagc     1740

agtacttcga cgaacacatg aaaacacaca ctggagagaa accctttatc tgtgaaatct     1800

gtggcaaaag cttcaccagc cgccccaaca tgaagagaca ccgcagaact cacacaggcg     1860

agaagcccta tccatgtgat gtgtgtggcc agcggttccg cttctcgaac atgcttaagg     1920

cccacaagga gaagtgcttt cgggtgacca gccccgtgaa tgtgccacct gctgtccaga     1980

tcccacttac aacttcccca gccaccccag ttccttctgt ggtgaacaca gccacaaccc     2040

caacccctcc aatcaatatg aatcctgtaa gcactcttcc ccctcggccc atcccccacc     2100

ccttctcaca cctgcacatc cacccacacc ctcaccaccc acaccacctt cccatccctc     2160

cagtccctca cctcccgcca cctccagctc tctttaagag tgagccttta aatcatagag     2220

gccagagtga ggacaacttt ctgcggcacc tggcagagaa gaacagttca gcacagcatc     2280

attaacatcc gtctccttag tgtgttctcc aggagacacg tccccatgtg tgagcgtgca     2340

cagagggagt cggtgagcat ttccttagtt ctcagactct cctccgcctc taccaagagc     2400

ttcgccagtg tcactgaatc aacagatcca agggaatgaa caagaagact accttgagct     2460

cacagaggga ctgtcatcta aaccagggga accactgaac taaagcccaa tttgcttgca     2520

ttttctgatg acttttataa gtttcaaata ctcagacttg tggaatttta taatttcata     2580

tcagctgatg aggtatgctt gcttttatat cccagacttc tcctcaaaga ggggataggc     2640

ctggtttcct ttgtactaat cgggaaggct gtgagattaa tccagagcat taattgtatc     2700

actgtgtatg gtaaggaatt cttttcagct tttggtgcca gctacagagt tgagctggcc     2760

atgtttcaca gtatatcaag cattatagag aaagacagaa attttcttct ttgtgtagct     2820

ctcctaacgc actctttatt ttactacaga aattatttta gagtttttgt atagacttct     2880

ttggtagtct gtttctaaaa tgaaatgtat ttcaataagc agtgtaattt tttcagtgta     2940

gctgaaccta tgttgtaaaa tagaaaaaaa tttttataat catcaaaatg tgattcttaa     3000

agatgcatat aacttctata attcaaagct attcttacat ccgtacaact caaaaggtgc     3060

ttcagagact agatgtatct gagagggtct ccagaccagg ttactgcaaa aatgaggttt     3120

tgctttcagg atttggcgta aatacttggt agttttgaca tctctgctta acactcaaga     3180

gaggctccct aatgtgctcc tgtcctccat gttctgcttg gcttcgttag tgcattacat     3240

gaaatgattt gcaggggatg gggccttttc cagggaagtc acctaaagct tgcatgtttt     3300

gaaaatttga ataaggctgt ttgctgacag gaggaggaag tagtggagat catttcatct     3360

cagtcacgtc tgtttctcac ttcccttagg aattgtgttg atgtttaact tttatgggat     3420

gacaaattga aatcgctcat tttgaggttg ctttattttt ctagaattgt tataagaagc     3480

taaaatagta aacttaaaat cacaaacatg acattgctga tagtggctga gaaattcaga     3540

tgagaagaca aattggttat gaattttgaa atatctatta tatgtaaaat gtggatatgt     3600

tcacaacctt gagctatttt aacacagttt aaatatagtg agggaaaact cctaagtttt     3660

actgccctgt cctctgcaaa ttatgtaata ccagcattct taggcgataa agagagcagc     3720

acctctagta cctttaggca gattactttt tcaagtttgg ggaacttcaa aagaccataa     3780

tcaaccagga gcttattata ggaaaggctg aacagaaggg ctagtgtatt gattacactt     3840

aacagatcat atttatccag actcagtata gcttaaaatt ttgtatttct ttatctgaga     3900

gaactgagtt cccaggctaa atcacttacc tcccaccccc tctccaattt tttttttaag     3960

agacaaggtc ttgctatgtt gcccaggcta gagtgcagtg gctattcaca ggtgcagtta     4020

tagcacacta cagcctccaa ctcttgggtt caagcaaccc tgcctcagct aaccaagtag     4080

ctgggactac aggtgcatgc taccatgccc agtccatttt ttaatcttga aatttcttca     4140

tttttctttc ttcggtttct taaaatcttt gcctgaatca gaacgctggc ttttatttat     4200

ttttttattt ttaatattaa atgtgcagat atgcttcgag cacttttcta actaatgagc     4260

tctgtggtaa gaaaaaatga actctttcaa ttgagattaa gtccatattt ttcaaacatc     4320

acgttctcta ttggcttttt ggtttagtgt ttctaaattt tctccttctg attttgcctg     4380

tcttatataa tgagcatagg aaaattttgg aatgaggcag aaaagtatat caagacatac     4440

ttcctggttt tggatgtaag ttttaaagaa tggtattttt aatatttgta cacattcttt     4500

gagcacccag gtacccaagc caataaggaa agttaattcc ttgcatatga ctgttatatc     4560

tttagtggtt gtctccctct ccctccacag tctccttggc attccatgac aagtttgtca     4620

acctacactt ttatatagac atatcattat ttcatggtca agcctgtagt attaaaatga     4680

tttttttaaa agatgtaaac tgtgcttagt taattggtta tattttgttc tgtttttttt     4740

tttttttttt tttttttttt gaggcagagt cttgttctgt tgcctgggct ggagtgcagt     4800

ggcgtgatct tggctcactg caacccccgc cccccgggtt caagtgattc tcctgcctca     4860

gcctcccgag tagctggaat tacaggcatg cgccagcacg cccggctaag ttttgtattt     4920

ttggcagaga tggggtttca ccatattggc caggctggtc tcaaactcct gaccttgtga     4980

tccgcccacc tcagcctccg aaagtgctgg gattacaggc gtgagccacc acgtccaact     5040

gccttatttt gttctgaata aatttacagt attgggcagc aattctggat tctagacttg     5100

agaccacaga atcaaccatt tcatgaggtt gtactgtaat tatacactgg aatattcagg     5160

tagtcatctt tgatttttca ttcaagtaaa tatagccata agaaaatatc tgctatacag     5220

gaaaaccagt attaagcaaa taccaccatc cttaacagaa acaaaaatat atatatatat     5280

tatttttaaa aattagcatt gtcatacagt acaattctta gtgaagtgta ttgtggaaca     5340

atttagaaac ttcctttttt tcccctagat taaggatact ttccttgact tgagacttgt     5400

ggtcttcagg aaaactactc agaatataat gactcctcat cagtatcata ttgtatataa     5460

ataatgaaat gcattaagaa tattcacaac attgaaccca ggaggcggag cttgcagtga     5520

gccgagattg cgccactgcg ctccagcctg ggcaacagag cgagactcca tctcaaaaaa     5580

aaaaaaaaaa agaatattca caacattaat gcttctgaat agaagaactg caggattaag     5640

ccttaaacat atatgtgcaa cacgtttaac atgcttaaga ctcaaactca gggttgaaaa     5700

tttggttggg gtcctctttg taagataaaa gttgcattat gtggtatgtt ctcttccata     5760

tatgctacag caccccatga attcttcaaa actttttacc tacttgttat ctgtttatga     5820

aaaaaagaat tatggagaag tttgagttct cagcccttat ctgtacatgt ctgttaaaga     5880

caacaaaggc tgcatttaag cattatatag ataacaaatt gaggctgtct ctcgttactt     5940

agttttactg tcttcaaagg cttgtatcat tgctagggtt aagacttatt tgaggatgag     6000

ttggcattgt attttttgtg tgtgtgggtt ggtttgtatt tgtttcgttt ttatttttct     6060

attttctctc atagatttat cagtaaaata taaactcttc cttagcctta ataaaggctg     6120

ctgctttctc aaattgagtc agataggctc attcggagtt agatttttaa atttgaatga     6180

agaaaagaca acaatttaaa ggcatgtggc ttcatttcca catatatttg tgactggatt     6240

cttattttta gcaagagggg agatcgccac aaaaaaaact ttagttcaaa gaagactgtg     6300

caaatcagtt acctgtactt tcatagtcta ccatttacat taactgttct agattaatga     6360

ctaagcatgg ccattaccat aattacatca tttttttaaa accacatttg ttcgaagtat     6420

ccttttctag tggttagaac tgtccctata atttgattgt ccctcatata ctaaccgaaa     6480

gcaaaatgct ctgatgagat gcttataaac tatgaatttt ttaattcttg aaattttttt     6540

cagtttttat gattgttgaa tagatatgta tgtttagttc cattattatt tcactggaag     6600

ttttaaattt tgagaagatg aagcagagat agaaatccat tgcagatata tgtatattta     6660

ccccatcttg caggtttcag ttagtaaaac acagaatgat aggtcggttt taatgtttta     6720

aaaaaaaact aaaaaactaa agttagagaa acctttctgt ttgagctact gtatagaaaa     6780

gacaactttt attgcattgc tggtccacat gataaatatt tcaatgctgt tctagactgt     6840

atgagaagta cttaatgaaa aaagggatac attacattta agaattgtat cagctaatta     6900

ctgttttaaa aaaatcaact catttggaat tcttcggact ataaaattga gcaagtaaag     6960

tttgggtttt aattttcctt tgcctgaacc aagataggaa attacttaag agtttttttt     7020

tttttttttt tttttttttt ttaggaatga aaggtcataa gccattagaa atagtggcat     7080

tattatgcaa taacaacacc ctagctaacc tgcttttgtc atctgtagca cttacaataa     7140

agaatgatga ccttccaacc ctggacacta cctcgataaa gcaaaccaga gatcctctct     7200

acactttcta tggaagccat aaaagttgcc atcaatatat ccactttcat agttctatac     7260

ttttatactt tctagacttt tttatagact ttatgatcag atctttttgt ctcagaggat     7320

aggttttgca agattcaaag gaaaatcaaa ctccttggtt gttccagctt tgaagctttt     7380

gcttcagtaa atttgtttaa agaaccagat cacataccat ttatcaaatt ctttacttaa     7440

gtcagaatac tttgcagaca tacatatttg gaaaacaaac tgtttcttgt tcactagata     7500

gaatctgtat tgtagtaaga aactacttac aaggtggctt tctttctgct ttgttactct     7560

atgtattact caataatata tgtatggtca caggttcctg gagttgtttt atttctttat     7620

gacagacaca tgagtatgca cctctctcta atcctctgat gtcactgcag cttcagtctc     7680

tctcactctg tttttgagtg ccttcaaaat gccagcatcc tggaacattc ttttcctgat     7740

ctaaatccta cctctgacta tttcattatc catgaatatt ggaattcacc catattccaa     7800

tgggcttaac tctacaaact agctaaaacc ttggacaaga attttgaccg tatttctgtt     7860

ttgttcctcc atgtcatttt taggttatat ttttaacttt tatttatatc ttatttcttc     7920

acatatttcg tctctctgtt gaaagatttt atccttattt gactcttcac tttttttact     7980

ttcaccagaa atttgacgtt cctttaaaat taaaggtcat tgaatgtctt ttgaacacct     8040

ttttctcaac tgaagtcttc ctgaatgcct cccctttctg atgaaaggat cctgagtgct     8100

gctgttgctc tgccctgttc ccatgtgccc actcccttcc gtacacattt tgcaagacta     8160

tactctttat tttagtcaaa ttaatttaaa attgctccct gggtttctgc tctctcatgg     8220

ccctgtccct caaaaacttc tgtttacttt ttctagctgt tttcatctaa tttgtttaaa     8280

atgtatgatg gatccataat atatgaagga tgtaatgaaa aggaggttgc agtgttttat     8340

ataatatgat cgagcacctc cgtgatgaaa catttagcaa ttggctagtc cttcacagcc     8400

agagtggaag tttgtgctgt ggacaggtct ttttactccc ttccagttct cctccaaaac     8460

tggagaaaaa ggaaaaaaaa aaagaactct ttcaaatgag gagatttgat tgcatttttt     8520

taggtgaatg aaagcttgga gttgagcatt tgggccttag tcagcatttt tcctttctga     8580

cttaaaatct catgtccttt tccttaaagt taatagtact caggttttta agactaataa     8640

ccacacaagg tgggtatcta agaaggcagc tgttaataca ttctccatct ttcctgtctg     8700

gcaacaggaa agatattatt ggtgagatag tgcaaaattg tgagaattgg ttatgtttga     8760

tgatgaataa attcaagatt tttgaaggct tcactgctat ttgggatggg aaggtgagtt     8820

tacaaaatga aaaaggtaga tttttatgtt acagaaatca gtaacgggtt tcttgttgtg     8880

ttaattacct ttcacttgat ttgccatgat gtttcttcct cattattgat ctagaagttt     8940

gcctcttgga tagtaactag taacttagta tctactttaa aatttgtggc ttttctcttc     9000

agggtcccag gccataaaac aacggagagc tgtacttgct tgtcacttgg aggaaccaca     9060

tccttgagac agcctgctgt cttgtatgtc ttcagtagga aacttctgac acacacattc     9120

aagggagttc ctgcccctga gaagtgttcc catagctttc cagtcgcagg ttactttcac     9180

actacgtcag cttctctggt gagatcaggg atgttacata ttacttgaaa atgatttcat     9240

aggaagtgag gatggggcaa gaaaggaggt agaagctgaa ttttgcttaa cttcagaagg     9300

aaatctgata cttgccttgg ctagttctga tcaactaaag agcctgtgtc tgtactggat     9360

gtgccaaaga gtcaagttgt ttctggaata tccagctcct ctgaatgaac acagcttcct     9420

ccctacctgt cttttatggg tgaaaaggga ccgtctgatg agcatgatag acatcctgta     9480

caggactcaa gactgtttca ttgcatttga aagttggtgg gaagtatttt attctgctag     9540

agctcctaac cctcctagaa atatcttttc atgctctatt aattcaattc attagtttaa     9600

aaagaaacag tgtgacataa ttttggtgtt tacttcttaa gttgtctccc caagggcata     9660

tatgtagcct ctgaaaatgg gatgatttct tctcaatctt ccataaattt gaatatgcat     9720

tttattcatt tcttgacatg ggctgtgtga ctgttttcca tcagcagttc tggctttgtc     9780

cacaagggag caataaagta cgttagcttt attctcaacc ttctaaagaa agatcccact     9840

tttaaatctc ttctggaata gcctcttagc tcaaagctta ttcatgtatt ttgattattt     9900

aagaaatttt cccttattac aaagtccagt cgtcgttcat ccctcatgat gccaagcaat     9960

gattgatgtg tgggtgtgga gtccttgtgg gtcaggcatc ttaattaatt agacttttta    10020

catattgatg atccccagat tgaaagccag gaccttccca taggggcgcc tttgtgtgct    10080

aaaggcagag caggcaggct tctccactcc tatctcctcc gcaggccacc accatcacat    10140

ctataggagg aacaagagca ctgggggaac tctggagtat gagtaaggaa atgcttctca    10200

ccttctctgc tccaaagaga tatctgttac atcagggaac aagtcctcta ggtcaggcac    10260

ttcctcctga ccagtgcaac gggcactcca ggttagaaac tgtgtgtgct ccctctctgt    10320

cagttacttg tctaagggct cctatccgtg gtcatcagct ctctggccat gagttctgtt    10380

tgtgcttatt gcagcagcat cttcacaaca aacaggtcag taatcaacct gggaagggaa    10440

aagacgacag taaatattac cccctgtaga gccgggaggc atttacacct ggaatggcct    10500

tcttaactga tttctgcctg gccacctcac ccccagccaa gtctgaacct gagcaatacc    10560

aggcacagag aggtgtctac ttgtaactcc aacacttgac aaaaaacaaa actgaagctg    10620

tgattggttt aggcagcaag tggccaggtg caacttgttt gtttttattt ttgttttccc    10680

caacagtact gagatcactt gcacttttcc tcatttctta agaaaatcca gtttgcttgc    10740

catgacttgt ttagcgttag gtttacaaag cttgttgttg aatgttgaat atttgtccaa    10800

aggagtttga caaaatagaa gctgcttggt ccctgttctg cctgctaggt cataaggatg    10860

aaggccatgt ggctggggta cttatgtcaa gtccagaatg gggcagtgtc cctctcctac    10920

ctctctgcgg agacgcaatt gaaggtcaag tagactcagt gtagggcagg cagctgtcat    10980

gctgcaaaga agtttagagg agtctttggg ttggggaggt gacaggtagg taggacagga    11040

tctcttaaga tgggaaagat actggggaga ggagggctgc ttggccccag ggaactgcag    11100

tgaggtggaa ctgagctccg ctcctgaatc tccaaaggag cccatgctgc ccggcttccc    11160

tgagtcattt tttccagcat cctgtcagat ccctcaatgt actgatttcc cccttgtgtt    11220

aactataccg atattatttt tttagcaatt gaaatgcact tttttatttc aactcaatca    11280

tgattttaag tataaaaaat ttatagattg ttaaaactac ttttttgtgt atttttaacc    11340

actcaatgta gcattgtata ttttattctt gtgagactct ggtacaggtg tgccgcctaa    11400

tgatttttct gagatgctgg gcctttggat gtgtacggta accaacttaa tgctaatgtt    11460

caaagtaaaa aaaaaaaaaa aaagcagcca ta                                  11492


<210>  1791
<211>  6184
<212>  DNA
<213>  homo sapiens

<400>  1791
ggcgacggcg gcggccgtcc tcatcccggc gcttgagagg acgcggggct gcgcaaatgg       60

cttgtcccgc tctcggtctg gaagctcttc agcccctgca gcccgagccg ccccccgagc      120

ccgccttctc cgaggcgcag aagtggattg agcaagtaac tggcagaagt tttggtgata      180

aagattttcg gacaggttta gaaaatggaa tcctcctctg cgagttgctg aatgctataa      240

agccaggact tgttaaaaag atcaatagat tgcctacccc cattgcagga ctggacaata      300

ttatcttatt cttgagaggt tgtaaagagc tcggccttaa agaatctcaa ctttttgacc      360

cgagtgacct ccaggataca tccaacagag taacagtcaa gagccttgat tatagtagga      420

agctgaaaaa tgtattagtt accatttact ggctgggaaa agcagcaaac agctgcacat      480

cctacagcgg aacgacacta aacctgaagg agtttgaagg attgttggct cagatgcgaa      540

aggacactga tgacattgaa agtcctaaac gcagtatccg agacagtggc tacatcgact      600

gctgggattc cgagcgcagc gactccctct ctcctcctcg ccacggcaga gatgattcct      660

tcgacagcct ggattccttt ggctctcgct ctcggcagac gccttcacca gatgtagtcc      720

tcaggggaag cagcgatggg agaggaagcg actctgaatc cgacttgcct catcggaagc      780

tgccagatgt gaagaaggat gacatgtctg cacggcggac ttcccatggt gagccgaaat      840

cagcagtgcc ttttaaccag tacctcccga acaaaagcaa tcagacggcc tacgtccccg      900

cgcctctgag aaagaagaaa gcagagagag aggaataccg caagagctgg agtaccgcca      960

cctccccgct gggtggggag aggcccttca gatacggtcc gagaactcct gtgtctgatg     1020

acgcagagag caccagcatg tttgacatgc ggtgtgagga ggaggccgcg gtgcagccgc     1080

acagcagggc ccgccaggag cagctgcagc tgataaataa ccagctgagg gaagaggacg     1140

acaaatggca agatgacctg gctcgttgga agagtcgtag aagaagtgtt tctcaggact     1200

taatcaagaa agaggaagaa aggaaaaaaa tggagaagtt actggctgga gaagatggga     1260

caagtgaacg aaggaaaagc atcaaaacct acagagaaat tgttcaagaa aaagagcgga     1320

gagagagaga gctgcatgaa gcatataaga acgctcggtc ccaggaggag gcagagggga     1380

tccttcaaca gtacattgag aggttcacca tcagtgaggc tgttctcgaa cgcttggaga     1440

tgccaaaaat tctggaaaga agccattcaa cagagccaaa tttatcctcc ttcctgaatg     1500

accccaatcc catgaaatac ctgcggcaac agtcactgcc tccacccaaa ttcactgcca     1560

ctgttgaaac caccattgct cgtgccagtg ttctggatac cagcatgtca gcaggcagtg     1620

ggtctccaag caaaactgtc actcccaaag cagtgcctat gctgacaccc aagccttact     1680

cccagcccaa aaattctcaa gatgttctga agacctttaa ggtagacggg aaagtcagtg     1740

tgaatggaga gacggttcat agagaggagg agaaggaaag agagtgtccc acggtggcac     1800

ctgcccactc cttaaccaaa tcccagatgt ttgaaggtgt ggccagagtg cacgggtctc     1860

cactggagct gaaacaagac aacggtagca tcgagatcaa cataaagaag ccaaactctg     1920

ttccccaaga gctcgcagca accactgaga aaacggaacc gaatagtcaa gaggacaaga     1980

atgatggtgg aaaatcaaga aaagggaata tagaacttgc ctcatcagaa ccacagcatt     2040

ttacaacaac tgtgactcga tgcagcccga ccgtggcctt tgtggaattt ccctccagcc     2100

cccagctgaa gaatgatgtg tcggaagaaa aagaccagaa gaaaccagaa aatgaaatga     2160

gtggaaaggt ggagttggtg ctgtcacaaa aggtggtaaa gccaaaatct ccagaacccg     2220

aagcaacgct gacatttcca tttctggaca aaatgcctga agccaaccaa ctacatttgc     2280

caaatctcaa ttctcaagtg gattctccaa gcagtgagaa gtcacctgtt atgacacctc     2340

agtttaagtt ctgggcatgg gacccagaag aggagcgcag gcgacaggaa aaatggcaac     2400

aggaacagga acgtttgctc caggagagat accagaagga gcaggacaag ctgaaagaag     2460

agtgggaaaa ggcccaaaag gaggtggaag aggaagaacg cagatactat gaggaggagc     2520

gtaagataat tgaagacact gtggttccat ttactgtttc ttcaagttcc gctgaccagc     2580

tgtctacctc ttcctccatg actgaaggca gtgggacaat gaataagata gacctgggaa     2640

actgtcaaga tgaaaaacaa gacagaagat ggaagaaatc attccaggga gatgacagtg     2700

acttattgct gaagactagg gaaagtgatc gactggagga gaagggcagc ctaactgaag     2760

gggccttggc tcattctggg aaccctgtat caaaaggagt ccatgaagac catcagctgg     2820

ataccgaggc tggggcccca cactgtggaa caaacccaca gcttgctcag gatccatccc     2880

agaatcagca gacatcaaat ccaacgcaca gttcagaaga tgtgaagcca aaaaccctcc     2940

cgctggataa aagcattaac catcagatcg agtctcccag tgaaaggcgg aagaaaagtc     3000

cccgagagca cttccaggct gggcctttct ctccctgttc tcccacccct cccggtcagt     3060

caccaaacag gtctataagt ggaaagaagc tgtgctcttc ctgtgggctt cctttgggta     3120

aaggagctgc aatgatcatc gagaccctca atctctattt tcacatccag tgtttcaggt     3180

gtggaatttg taaaggccag cttggagatg cagtgagtgg gacggatgtt aggattcgaa     3240

atggtctcct gaactgtaat gattgctaca tgcgatccag aagtgccggg cagcctacaa     3300

cattgtgaca cggctttcaa gcttccggat cactcaccat ttctttactg agagtgtccc     3360

ctggcaactg cttaacaaaa tcccaagctc aggggcttct cagcatttac ctaatttctg     3420

aaaggctctt ctgaaaggtg gtatctgttc tttcgtagca cagtgtttat gtttttcctg     3480

tttattgttt tggttttttt tttttttttg catttgcaca gtatacacaa aagaatatgg     3540

ggttgtaatg atcctgaata gctcaaaaaa ggttttagca tggtcaaaca ggcttatggt     3600

ttaaaatgtg ttattctctt ctttgggaat tagctaaatg atgcaataaa cctgttttgt     3660

tttagaatgt ctaggaatta aacactttat gtttacagaa ttgagctgca gaaagtgcaa     3720

gacatgccaa tttgagacac acggtcttct aagactgaag gataaattta atgcatttca     3780

gaaactaaac atcacagcaa gctctatctc tgagctataa tttgttttta atgcaaagac     3840

actagtttga taatatatac tgtaatcctg aaacatttgt gttacttacc tttggaggta     3900

gaaattatac caataaatta ttgcaccgtt agtattagat tctgtgtacc ttggaagtta     3960

tgtcattaat ataggctggt tcatcaaata aagcaaaacc ttgcaatatc agctagattt     4020

acactccggg acgttgccca aaggtaggaa gaaagcagag ggaaatattt cagtcatcat     4080

ttccaaagtc attatcaaaa tctgtgagga agtttaatct tccaaagagt caatgtcaga     4140

catcaggcct ctgttgcctg cttctctcga ggcactagat taggagtctt caataagaga     4200

cttaacatga ggtatatgga agatgaggca ccgagataag ttcatcatta ggtgtgagca     4260

ctgctcaccc ttgctggcaa gttctcctta agggcctgaa gcacaggtgt ccaaagaaaa     4320

gcgttaagtc catcttaata gaatctatgt ggtatatgat gtggtcagcc cctggtctgt     4380

gatcagcaag aacctacagc acagattatg ccctgcccac ttcaatgaat acctactctc     4440

ctccattctc catcactttt tttgctatca agaactccgg accttgccca tggagaagtt     4500

tagagaggaa ctcttgtgga gagctggttt attttctgcc ctgtgcgacg agtttcagct     4560

ggccaagaaa ggagtcaagt tattaaaaag catcacaatg tagatctcca ggctggtttt     4620

ttgttttttg ttgttaagac tggggaaagg gggactattt attctgcctt aaatcaatgg     4680

caaataagtc aagatgacat tttgtgaatg tagactatgg atacactcct aatagattga     4740

tgtagtcata aaagggggtc aagtagatgt ttttctgtta tgtaagcaat aatttttccg     4800

tgtcttattg agtatggcta gcgattattt attacatgct agatgggttc tttgcatgtg     4860

ggttccatat aggtgcagaa atttcctcag ccactggagg gatttcgacc atatttgtca     4920

tttggatgag ctgttattag attgaaatct acacatcatt tcattaaaaa ttgtgcctta     4980

gaaaacgcaa agctgttgca catggcgata aattatggat gcagtacatt gaagagagat     5040

gaagtcactt ccaagtttcc aagacttctc atggaggtgt ttgctgtttt acaggaaaaa     5100

ataaaaataa aaaaagaaaa aaagaaaaaa ttaaaaagaa aaattgtttt gaaaatgtac     5160

agatcaagtc caatattttg attatccacc tgcatgtttt attaaatatt ttgataatgt     5220

ggatgtttac actttgcatg atattagcag agtaccacta gtaatgcaca aacatgtaca     5280

atatggtcat tcataaccga tttttataga atacttttta catgtgcaac tccatccgtt     5340

atgtaaggat tacatgaata ttgcacattc ccttctggtt tcacaaaccc atttatacat     5400

atttcttagt gaggctcatt gtacatgtat tgaagctaga atcgagtcaa gaaaaataaa     5460

gccccattct ccaactgcaa aatgtgcttt cccataatga acactagtca ccagcacaga     5520

ataatctcca acattttcta aattctaatt gccaactgtt tctatttata tttgatttat     5580

atttcatttg gagtctgtta catggcagct taggcagact agatcttgtt ttttccaatg     5640

cagcataatg agtatgatct atttcttttc aaataatctt tgagatccca ggaaaaaaaa     5700

aatgctctgc tccattgagc tataatgtaa atgtgtttgt ttaaaaaaca ggtgaggcaa     5760

gtgagtgatt tattgttcct gaggaagtat atctgatttt ttttctcata ctccaaaagc     5820

tagtccctac tctttaataa aaataatggg taactttttg tttttcacta gcgaacttcc     5880

atgacatttc ctttctatgt agtgtgatta atgcaataca tattatagtt atctatacac     5940

agtgtaagat ttaacaaact gaaatgatcc acctcatatg tgagtccgtc caaaagatgt     6000

tactgctctg ggtgggccag tgttctatat cggttatact aactttcatt taaagtattt     6060

attctaaaat gcctctgaga aacagtaaaa aataaaaaca acaagttgtc taaaatgcaa     6120

cagcttttat agtaaatgta catttataaa taaaatactc aaatcaaaaa aaaaaaaaaa     6180

aaaa                                                                  6184


<210>  1792
<211>  3390
<212>  DNA
<213>  homo sapiens

<400>  1792
agaaggggaa acaggaatcg attaggaata aaggattata atccactttc cttctgagga       60

aaagctggga accttctcat tttgccttat gaaaactaag ctgaatcgac tgctgccaaa      120

catctattag gcaaaattgg cctcttgccc atgatttgac tttccagcac agccagttct      180

ttttctcctc tgcagctgat tggctctgga gtgtggccag aagcctctct cctgcaatta      240

aaggagtcgg gtctctaact gttgatctgt ttttttccct tctgagcaat ggagcttacc      300

atctttatcc tgagactggc catttacatc ctgacatttc ccttgtacct gctgaacttt      360

ctgggcttgt ggagctggat atgcaaaaaa tggttcccct acttcttggt gaggttcact      420

gtgatataca acgaacagat ggcaagcaag aagcgggagc tcttcagtaa cctgcaggag      480

tttgcgggcc cctccgggaa actctccctg ctggaagtgg gctgtggcac gggggccaac      540

ttcaagttct acccacctgg gtgcagggtg acctgtattg accccaaccc caactttgag      600

aagtttttga tcaagagcat tgcagagaac cgacacctgc agtttgagcg ctttgtggta      660

gctgccgggg agaacatgca ccaggtggct gatggctctg tggatgtggt ggtctgcacc      720

ctggtgctgt gctctgtgaa gaaccaggag cggattctcc gcgaggtgtg cagagtgctg      780

agaccgggag gggctttcta tttcatggag catgtggcag ctgagtgttc gacttggaat      840

tacttctggc aacaagtcct ggatcctgcc tggcaccttc tgtttgatgg gtgcaacctg      900

accagagaga gctggaaggc cctggagcgg gccagcttct ctaagctgaa gctgcagcac      960

atccaggccc cactgtcctg ggagttggtg cgccctcata tctatggata tgctgtgaaa     1020

tagtgtgagc tggcagttaa gagctgaatg gctcaaagaa tttaaagctt cagttttaca     1080

tttaaaatgc taagtgggag aagagaaacc ttttttttgg ggggcggttt ttttggtttg     1140

ttgttggttt tttttttttt tttggcggga agaaagagtt ttgctcttgt tgcccaggct     1200

ggagtgcaat gacgtgatct ccgctcactg caacctccac ctcgcgggtt taagcgattc     1260

ttctgcctca gcctccctag tagctgggat tacaggtgcc caccaccatg cccagctaat     1320

ttgtattttt agttgagaca gggtttcact acgttggcca ggctggtctt gaactcctga     1380

tctcaggcaa tccacccacc tcagcctccc aaagtgctgg gatgacaggc gtgagcaacc     1440

gcacccagct taaggttttt ttgttttgtt ttgagacgga gttttcgctc ttgttgccca     1500

ggctggagtg caatgctgtg atctcagctt accacaacct ccacctcccg ggttcaagtg     1560

attcacctgc ctcagcctcc tgagtagctg gtattacagg catgcgtcac cacgccggct     1620

aattttgtac ttttagtaga gatggtgttt ccccacgttg gtcagtctgg tctcaaattc     1680

ctgacctcag gtgatctgcc tgcctcggcc tcccaaagtg ctgtgattac agacgtcagc     1740

caccatgcct ggcctgaaac cttttttagg taaagttgaa ttccatcctt aaaagtttct     1800

gttatatcct atttagccat tttctattgt ctcccaaaga attcacatca aaaaaacagc     1860

tttgaactcc cccttcaaag gaaacagtcg actttcataa ttagcatcta ccattatccc     1920

caaatcttat tttattcatt gacttgaaat tttttccaat tgcttttttt tttttttttt     1980

taaggttaag agcagaggtt tactaggcca aagaaagaga atagctctct gttgcagaga     2040

ggggtcctgg agaaatgggt taccccagtt gtcttattta aatggttacc catcagattt     2100

taattttatc ttctctttga gagcttggta ataagaagca cttaaatcac tccaaagaag     2160

actttaaaaa gggagcagtg aaaaggtctt aataatttat tgattgaatt aagaaatact     2220

agctaattaa gaatctgagt ctaaacagca cagatttttt ctttctgctt ttaaattgtg     2280

ttttaaaaaa agagacaggg ggctgggcgt ggtggctcac gcctgtaatc ctagcacttt     2340

gggaggccga ggcgggtgga tcacgaggta ggagttaaag accagcctgg ccaacatggc     2400

aaaaccctac taaagataca aaaaaaaaaa aaaattagcc aggcgtggtg gtgggtgcct     2460

gtaatcccag gtacttggaa ggctgaggca ggagaatctc ttgaacccag aaggcgaagg     2520

ttgcagtgaa ccgagatcat gccattgtac tctagcctgg gtgacaagag caagactccg     2580

tctcaaaaaa aaaaaaaaaa aaaaaaagaa gtagagacag ggagacaggg tctcactgtg     2640

ttgcctaggc cggtcttgaa ctcctgggct caagtgattc tcccaccttg acctcctaaa     2700

ttgttgggat tacaggtgtg agacagtgca cctggccgaa atagctcaag tttctgaaaa     2760

acaaatctga atctatttgt tattcttagc gtcactggtc tggctttcag aattaacata     2820

caaggttgcc acacctagtt ctgcccagct ttatgtcttt tattccagta ttccaccaaa     2880

gtttgttttc ctgcattcca gttctcaagt cttaagataa agattgtact tgacagttta     2940

gtatatccat aaaactattt gaggtggtta aggttcttgg gttcattttc cttaatactt     3000

tgctgaatat tgtagattgt aggcaatgaa aaagtctact aaattaggaa aaccttgaat     3060

aattaggtat cctaggtaag agcccctaaa catcaagcaa tctgtgagtc tgtaaagaaa     3120

taaatatttt ttggattatt cttatctaat tccacccctg ttggaagatg atttctttgt     3180

tctttgcaac tatggaagct gtgaaaatca tcacaagtgc ctctgaaagc gagtgttagg     3240

ttggttagag ggtttaatat tttctgcaat ggtttgtagg aattttaata aatgtagtat     3300

attttctgag atgattttgt aaaagtacta ttttaaatat caaatcaacc aataaattca     3360

catttgtgtt aggaacagaa atatggttta                                      3390


<210>  1793
<211>  1405
<212>  DNA
<213>  homo sapiens

<400>  1793
tttcccggcg tccatttagt ggcgggaaaa gcgacctttt ctgagcgcgt ttgcctgttg       60

agtggtagcc tttcccctca accagcaatg gaggagcagc cccagatgca agacgccgac      120

gagcccgcgg actccggagg ggaaggccgg gcaggcgggc caccgcaggt cgccggcgcc      180

caggcggcgt gcagcgagga ccgcatgacc ctgctcctca ggctgagagc acagacaaaa      240

caacaactct tagaatataa atcaatggtt gatgcaagtg aagaaaaaac tccagaacaa      300

attatgcaag aaaagcaaat cgaagctaaa attgaagacc tggaaaatga aattgaagag      360

gtaaaagttg cttttgagat aaaaaagctt gcattagaca ggatgagact ttcaactgca      420

cttaaaaaaa acctggagaa aattagcaga cagtctagtg tgctcatgga taacatgaaa      480

cacctattag agctaaataa attaataatg aaatcacagc aggaatcttg ggatttagag      540

gaaaaactgc ttgatattag aaagaagaga ttgcaattaa aacaagcttc agaaagtaag      600

cttttagaaa tacagactga aaagaacaaa cagaagattg atttggacag tatggaaaac      660

tcagagagga taaagatcat acgacaaaac ctacagatgg agataaaaat tactactgtt      720

attcaacatg tgttccagaa ccttattttg gggagtaaag tcaattgggc agaggatcct      780

gcccttaagg aaattgttct gcagcttgag aagaatgttg acatgatgta ataagaattc      840

atttctgaca tattttacat ttctggcaat ctcaactctt atttggaata cttctgtgca      900

tttgtctgtc caccgtaatt ttagaaaagc atatccataa cgtttacagt tgtagtacag      960

ttgtggttag ttatttgtag tgggattgaa agtaattttt ttctttttat atttctatat     1020

ttagtttgtt tttttgttgt tgttgttttt tgagatggag tctcgctttg ttgcccagac     1080

tggagggcag tggcgcgatc tcggctcact gcaacctctg cctcccgggt tcaagcagtt     1140

ctgcctcagc ctcccaagta gctgtgacta aaggtgcacg ccgccatgcc cagctaattt     1200

tttgtatttt agtagagacg gggtttcacc gtgttgccca ggctgctctc agaactcctg     1260

agctcaggca gtccaccgcc tcggcctacc gaagtgctag gattacagac gtaagccacc     1320

gagcctggtc tagtttgcat tttttttcta tcagttttat aagttaagaa ataaaaggaa     1380

ttaatgttaa aaaaaaaaaa aaaaa                                           1405


<210>  1794
<211>  3159
<212>  DNA
<213>  homo sapiens

<400>  1794
caaccccacc cagccctcag acccttccag ctgccgctgt cgtctttgct tcagccgcag       60

tcgccactgg ctgcctgagg gcgttcgatc cctagaggga ggagcctgtc caaacggacg      120

ctaacggcct acctccccct caggtgctct tacagcctgt tccaagtgtg gcttaatccg      180

tctccaccac cagatctttc tccgtggatt cctctgctaa gaccgctgcc atgccagtga      240

cggtaacccg caccaccatc acaaccacca cgacgtcatc ttcgggcctg gggtccccca      300

tgatcgtggg gtcccctcgg gccctgacac agcccctggg tctccttcgc ctgctgcagc      360

tggtgtctac ctgcgtggcc ttctcgctgg tggctagcgt gggcgcctgg acggggtcca      420

tgggcaactg gtccatgttc acctggtgct tctgcttctc cgtgaccctg atcatcctca      480

tcgtggagct gtgcgggctc caggcccgct tccccctgtc ttggcgcaac ttccccatca      540

ccttcgcctg ctatgcggcc ctcttctgcc tctcggcctc catcatctac cccaccacct      600

atgtccagtt cctgtcccac ggccgttcgc gggaccacgc catcgccgcc accttcttct      660

cctgcatcgc gtgtgtggct tacgccaccg aagtggcctg gacccgggcc cggcccggcg      720

agatcactgg ctatatggcc accgtacccg ggctgctgaa ggtgctggag accttcgttg      780

cctgcatcat cttcgcgttc atcagcgacc ccaacctgta ccagcaccag ccggccctgg      840

agtggtgcgt ggcggtgtac gccatctgct tcatcctagc ggccatcgcc atcctgctga      900

acctggggga gtgcaccaac gtgctaccca tccccttccc cagcttcctg tcggggctgg      960

ccttgctgtc tgtcctcctc tatgccaccg cccttgttct ctggcccctc taccagttcg     1020

atgagaagta tggcggccag cctcggcgct cgagagatgt aagctgcagc cgcagccatg     1080

cctactacgt gtgtgcctgg gaccgccgac tggctgtggc catcctgacg gccatcaacc     1140

tactggcgta tgtggctgac ctggtgcact ctgcccacct ggtttttgtc aaggtctaag     1200

actctcccaa gaggctcccg ttccctctcc aacctctttg ttcttcttgc ccgagttttc     1260

tttatggagt acttctttcc tccgcctttc ctctgttttc ctcttcctgt ctcccctccc     1320

tcccaccttt ttctttcctt cccaattcct tgcactctaa ccagttcttg gatgcatctt     1380

cttccttccc tttcctcttg ctgtttcctt cctgtgttgt tttgttgccc acatcctgtt     1440

ttcacccctg agctgtttct ctttttcttt tctttttttt tttttttttt ttttaagacg     1500

gattctcact ctgtggccca ggctggagtg cagtggtgcg atctcgactc actgcaaccc     1560

ccgcctcctg ggttcaagcg attctcctgc cccagcctcc caagtagctg ggaggacagg     1620

tgtgagctgc cgcacccagc ctgtttctct ttttccactc ttcttttttc tcatctcttt     1680

tctgggttgc ctgtcggctt tcttatctgc ctgttttgca agcaccttct cctgtgtcct     1740

tgggagccct gagacttctt tctctccttg cctccaccca cctccaaagg tgctgagctc     1800

acatccacac cccttgcagc cgtccatgcc acagcccccc aaggggcccc attgccaaag     1860

catgcctgcc caccctcgct gtgccttagt cagtgtgtac gtgtgtgtgt gtgtgtgtgt     1920

gtgtgtgtgt gtttgggggg tggggggtgg gtagctgggg attgggccct ctttctccca     1980

gtggaggaag gtgtgcagtg tacttcccct ttaaattaaa aaacatatat atatatatat     2040

ttggaggtca gtaatttcca atgggcggga ggctttaagc accgaccctg ggtccctagg     2100

ccccgcctgg cactcagcct tgccagagat tggctccaga atttttgcca ggcttacaga     2160

acacccactg cctagaggcc atcttaaagg aagcaggggc tggatgcctt tcatcccaac     2220

tattctctgt ggtatcaaaa agaaaaaaaa aaaaaaagaa ggagtcgggg ccgggcgtgg     2280

tggctcacgc ctgtaatccc agcactttgg gagaccaagt caggcaatca tctgaagtca     2340

ggagttcaag accagcctgg ccaacatggt gaaagcatgt ctctattaaa aatacaaaaa     2400

ttagccgggc gtggtggcgg gcgcctgtaa tcccaggtat ttggggggac tgagacagga     2460

gaatcccttc aacccgggag gtggaggttg cagtaagtca agatggcacc actgtgctcc     2520

agcctggggg acagagcgag actccatctc aaaaaaaaaa aggaatcgga cgaagaacca     2580

caggatgttg aagacaactg tctgaagtat ttgtgaggga cagcgatgtg gccctctgtg     2640

ttaagaataa cgtgtcctgc tttggcagag agaagaaaat agccactgcc cgctttcaag     2700

gcaagatcga ccttttctgt tttgttttgt ttttctttct ttttcctggc catgaggaca     2760

aaaattactg agtggccctt aaagagggaa gtttgttttc agctgttctc ttttgcccgt     2820

aggtgggagg gtggggattg ctgcgtccta gctagaggaa tggctttgct tgaatgtgta     2880

gtgcacacgc acgggtgttt ctgtgtgcta gttgcttctt gctgctgctt cctgcttgtc     2940

tgggactcac atacataacg tgatatatat atatatatat ataaatgtat aaatatatat     3000

tttatttttt tttaaatccc tggagcttct ggttcctatc agttcctgtt gttaatcgta     3060

gaaccgttgt cccttccccc attcccgtat ccatcatgtt ctttttcttt taaatatcaa     3120

tataaaggta aaagaaaaaa aaaaaaaaaa aaaaaaaaa                            3159


<210>  1795
<211>  3649
<212>  DNA
<213>  homo sapiens

<400>  1795
aaggaggagt gcactggccg ggatcggtgc agcgctcaca ctcactcaca gtcactctct       60

ctgagcgcgt ctcgctcgct ctcatacacg cccggagccc aggagcgctc aggatcccga      120

gcgccgcgaa aaagttcccc cggcttttgc tggagactca tcgctttggg aagtgcattt      180

gcttcgtggc tccgccgagc ctgctgaatc ctgtcctcgc ggctcgggac cccgggatcg      240

ctgaccgctg ccgccgccgc ctctgcctcc cggactatcg gcagcctcgg caacaatagt      300

ggcggccgcc cccagcgagg ctccgggagc ccttgcctgc gggggtccgg ggactcgagc      360

cggcctccgc ctcccggacg cacagccagc gtggtccccg cgtgcaacgc gagcgccggg      420

gagtggctcc tgctttgccc ctcgtggggg ccgagccaag accagtctgc aaactccatc      480

ccgccggctg gaagaagtcg cggagccggc accaaacccg cagcgtcttc ccgcgcggat      540

cccgggactt aaaaagccgg ggccaccccg gcccaggacg ggatgcgggt cggtccggtg      600

cgctctgcca tgagcggcgc ctcgcagccc cgcggcccgg ccctgctctt cccagccacc      660

cgaggcgtcc cggccaaacg cctgctggac gccgacgacg cggcggctgt ggcggccaag      720

tgcccgcgcc tctccgagtg ctccagcccc ccggactacc tcagcccccc cggctcgccc      780

tgcagcccgc agcccccgcc tgccgctccg ggggccggcg gaggctccgg gagcgcgccg      840

gggcccagcc gcatcgccga ctacctgctg ctgcccctag ccgagcgcga gcatgtgtcc      900

cgggcgctgt gcatccacac tggacgcgag ctgcgctgca aggtgtttcc cattaaacac      960

taccaggaca aaatcaggcc ttacatccag ctgccatcgc acagcaacat tactggcatt     1020

gtggaagtga tccttgggga aaccaaggcc tatgtcttct ttgagaagga ctttggggac     1080

atgcactcct atgtgcgaag ccggaagagg ctgcgggaag aggaagccgc ccggctcttc     1140

aagcagattg tctccgccgt cgcccactgc caccagtcag ccatcgtgct gggggacctg     1200

aagcttagga agttcgtctt ctccacggag gagagaaccc agcttagact agaaagtcta     1260

gaagacacac acataatgaa gggggaagat gatgctttgt cagacaaaca tggctgccca     1320

gcctacgtga gccctgagat cctcaacacc actgggacct actccggaaa ggctgcggac     1380

gtttggagcc tgggggtgat gctctacacc cttctggttg gacgataccc cttccatgac     1440

tcagacccca gtgccctttt ctccaaaatt cggcgtggac agttctgcat tcctgagcac     1500

atttccccca aagccaggtg cctcattcgc agcctcttga gacgggagcc ctccgagaga     1560

ctcactgccc ccgagatcct actgcacccc tggtttgagt ccgtcttgga acccgggtac     1620

atcgactcag aaataggaac ttcagaccag attgttccag agtaccagga ggacagtgac     1680

attagttcct tcttctgcta atccccaaaa cctcagaaac ctcataattc ttaacacctg     1740

gcatttccat ttctaaagat ggacaggccc tttggcgtgg taccaaccag ataatgactg     1800

catcaggatg aaagctgctg aactcggcat ggcgcctcct cttctctgtt gggatgagtg     1860

actttattga tttgagcagc atatgctgtg attggctgcc ctgcaaattt gtttccctta     1920

aggaaccctc accaactatc tctgctggat ttgggagttc cgcatctttt gtggagggca     1980

gagtatggac atcttacacc cggtggtcaa gtgtgtaata aacttgagca ttcgaatggg     2040

agaaaaagca aatcgcacaa tgacatattt tgagtaataa ccgtattttt cacagggtga     2100

caaattgggc caataaatct gccatctttg aactcatctt tggtggctag actgctacgg     2160

cagcttctct gatgggaaag ttcctttttt ggcttaacac tcaccctttc ttcacactca     2220

catttaccaa tgactctgct ccgtttttgg agcagactgt tttaagttgc tcaggagcct     2280

gatggaacca tgaaccgaga ctcttctctg tttcctgcca agacctcatc tgcactaatg     2340

ccttctccct gaccttgaca cttccccctt tagctataaa agcacttacc agccgaacgt     2400

ggaacagtat cacaaaagat tccatctccc aacgatttca gaactctgag ctcagagaga     2460

ctccagattt taaaaaataa tttgagtgct tggaaactat tagcttttta agttccttcc     2520

aaatatgtta gtacctaccc tttacttttt ccccaagacc atctcagggt ggagcattct     2580

gtctaagaga agaaagataa ggaggctccc acccacctct cccaagagca gacattaaac     2640

atctttgtgc tttgaagaga gtgaattttg gatagtcttg tgattctcag actaacttcc     2700

agaattatac tttaacccct cccagatatg gtccgccttt ggcattgtgt gtacatctgc     2760

agttttgcat ggtgggttgt taatatttca aatgtgtggt ttatgaatac gtctgtataa     2820

tcggcttctg gagtgaaaca gcaaacccca aatcttcaaa gttggaagga actttaaaaa     2880

tcatccggtc caatctcttt cctctttctg ccacctccca aggcagaaat cccctcttca     2940

gcttcttttg taggtgggaa tccagcctct gttagatatg tccagagatg gaaactcact     3000

cccctacaaa agatggagct taatggagaa attgcaactt tcattaaaaa acaaattcag     3060

atgaaatatc agtaactgtc ttggacagtg ctgaaatcag gtggttaaac gggtaaacaa     3120

aatatactgt attttgagaa atggcacaaa aacaggcagt catctttaag ggctatgcct     3180

aggcaaacta ctaacatgca ttgtgagaat gccgtgtata cctcacgtac tgtgtacttt     3240

gtacatatat tttacctttt atacctatgt tcgattttgt tttgttttgt tttgttctgg     3300

ctttgaggct tgttttgttg tctgtgtctg tctgaataac ctgcgtgtct aaaaccacgt     3360

gaaatgtgaa tgattattgg caatattacc ttgacagaat catgggactt tgagaagagg     3420

gaggacagag gcctctgtcg cactaacgct ctcgtggttg ctcgactgtt gtatctgtga     3480

tacattatcc gactaaggac tctgggctgg cagggccttc tgccgggaaa gctagaaaca     3540

ctaggttctt cctgtacata cgtgtatata tgtgaacagt gagatggccg tttctgactt     3600

gtagagaaat tttaataaac ctggtttcgt aaataaaaaa aaaaaaaaa                 3649


<210>  1796
<211>  4442
<212>  DNA
<213>  homo sapiens

<400>  1796
aagggcgctc cgcgagcccg tctctcctcg aatgaaagga aacaacctcc ggcgacagag       60

ccccgctctc aggcactgct ggagaaccga gaccgacttc tttctcttta ccctcattgg      120

cgcttctctc ctgcagtccg cctctgggcc ctgccgcatt tcttgagact taaagtggca      180

ttctaaaggc aatttaaaaa tcatgtcaag ctcagttgaa cagaaaaaag ggcctacaag      240

acagcgcaaa tgtggctttt gtaagtcaaa tagagacaag gaatgtggac agttactaat      300

atctgaaaac cagaaggtgg cagcgcacca taagtgcatg ctcttttcat ctgctttggt      360

atcatcacac tctgataatg aaagtcttgg tggattttct attgaagatg tccaaaagga      420

aattaaaaga ggcacgaagc tgatgtgttc tttgtgccat tgtcctggag caacaattgg      480

ttgtgatgtg aaaacatgtc acaggacata ccactaccac tgtgcattgc atgataaagc      540

tcaaatacga gagaaacctt cacaaggaat ttacatggtc tattgccgaa aacacaagaa      600

aactgcacat aactccgaag ctgatttaga agaaagtttt aatgaacatg aactggagcc      660

ctcatcacct aaaagtaaaa agaaaagtcg caaaggaagg ccaagaaaaa ctaattttaa      720

agggctgtca gaagatacca ggtccacatc ctcccatgga acagatgaaa tggaaagtag      780

ttcctataga gataggtctc cacacagaag cagccctagt gacaccaggc ctaaatgtgg      840

attttgccat gtaggggagg aagaaaatga agcacgagga aaactgcata tatttaatgc      900

caagaaggca gctgcccatt ataagtgcat gttgttttct tctggcacag tccagctcac      960

aacaacatca agagcagaat ttggagactt tgatattaaa actgtacttc aggagattaa     1020

acgaggaaaa agaatgaaat gtacactttg cagtcagcct ggtgctacta ttggatgtga     1080

aataaaagcc tgtgttaaga cttaccatta ccactgtgga gtacaagaca aagctaaata     1140

cattgaaaat atgtcacgag gaatttacaa actatactgt aaaaatcata gtggaaatga     1200

tgagagagat gaagaagatg aggaacgaga gagtaaaagc cgaggaaaag tagaaattga     1260

tcagcaacaa ctaactcagc agcaacttaa tggaaactag gttcatggga cagagttaga     1320

aaactgggaa tgaataagac atccataact actattcttt tttcactgtt ttctaaaatc     1380

aaaaagggtt tgtaactttt tactgcccaa ctcttagatc cttcattgaa ctgcctaaaa     1440

atgtcttgtt tgttttatga gccctcacta gaaggctgag tttgacatgt tgatattacg     1500

tagctatagt ttgcagtttc tgggaagcaa ttgaaacact attaaccctg tgtatagtgt     1560

caacagttaa agcagacgaa acgaagtaag ctatatttct ggactgaaca aagctctgct     1620

gtttagagca tttaagtttg tttagtggat ccatactcaa aggaaagcat aagcaaattt     1680

tcctttacaa tgcaaacatg ccactggtgg cagcacatgg taatttgtgg attttttttt     1740

catactcaag taatggaggc tagaaatgaa gagaaccttc tttttctctt gactttgaca     1800

gcacatgcta aaaatctctt ccaagaagta tgctaaagct tttcatttgg ttcctgttaa     1860

agttgttctc actgaccagc atggactcag gcaactggta atgataagct atgagctcca     1920

gtgcttttgc caaaattctc ttgacagcac acctcctctc tttccatgtt atacaaagga     1980

cttctggcaa aatgattgag tccttcaagt ttaaactaac atttggcaac agcaaattaa     2040

acgtttttaa gatgtaaaga aagggttacc gcttgctaag gacttcagac accatgtccg     2100

aaacctgttc ctctcaagtg ccctgttgtg tggaacactt cacatattgg cgcacagtac     2160

gtaaggaggt ctcatgtgct gtaggagtaa aaaagtcttt gcataaaaca gtatttattt     2220

ttacttttgt gaccactatt ttagaaactt tatttaatat tttaatgttt tcagtcattg     2280

ctttggttat ctataaaata ggcttttgtg ccctactttt cttcttgtag ggcttggtgg     2340

tgttttatcg attgtcagaa ttgtttttga aagcctaaga acccagcttt ttagaaagga     2400

ttttcacact ggcatttcta ggtagtgata ttttcttcca cttacctgct gaagcacatt     2460

tatgcatttc tttatggcaa aaccaaataa ctttagttgt ggtctgcctg atactaccat     2520

agcacctcag taccaagggg agggattttg actagttgaa ttattaagcc accacaataa     2580

agcagatttt taaataagaa ataataatgt taacttgact gtacattgag atattctgca     2640

gctgatagag cagcatttta aaaatgtaac aggtggaaaa ttacactgtg cttaatgact     2700

gatttttttt taaactgcga gtcccttaag atcacgtttg tcaagtgtgt attcacacat     2760

ttacttaaat caagggactc aatgcttgct tttattttaa ccatctttta ctatttttag     2820

aaggaaacta gctttagtag tgggttgccc tgtatgtttt ctctttttgc tcttaatatg     2880

ccattgggtt tttgtgtgta tgtgattttc aaaattcatg acttgaagtg caaggacaga     2940

tctagatgtt tgtttaccaa gctatgtgac ttctcccaaa ggatctgtac tttctttcct     3000

tacaacagct tgaaaatcat tattttaaaa tccttaaatc actgtgtcta gatcattttt     3060

tacattgtgt gccatagact tacccatggg acaacagagc tccttcattt ttggacaact     3120

actgtaatca tttttttttt aggaaaaatg gaaggtgccg ggggtaatca tggccagtca     3180

ataattatat aaaggagttc aaatactata gctgtcagtt gatgaatttg ttatgtagta     3240

aaatgtatga ctttgtatgg gtttcttcag ccctttttct gccactagca accagaatag     3300

cactttacct tttggttggc tagataagtg gctgactacc tgtttttctc actgtggtgt     3360

gattggctaa acaatctcgc attaaaaatt caaatgtaaa ttgaattcac atgaaaaatc     3420

atgtttggtt gtaaacctcc aatgttttga ttctctaatc atgttttcgt cacatgctga     3480

gtaaaagtgc cttacaatgt aaaaattgta cagtacttat gttcccaagt agcatcatca     3540

tcttctgggt agtaattaca ttgtggtatt aatatttaga aaaatggacc tcagcagtgt     3600

atttactgta catctcttaa gtccttaact gtagttttaa taagcatgac attatttgat     3660

aagtatataa catttacatc atttcaaaaa atactgccgt tactgtcttt tatgcatatt     3720

ttagcctgaa attttgaagc gtcttttttc tttctttttt ctttttttgt tttgtttttt     3780

gttattgata ttaaacagtg taatctttgc aagcgtatat tgaagattat tctggagcat     3840

ttattgcctt accagaaatg ttagtaggaa atgttcttta gagtagaaag atagacttga     3900

gtttctatac ttttaagaag agctctttgt tcctggggga ggggggcagg gggtgaattt     3960

tactttcatc tcaagttatt aaaaacccac aactgaagta aattttattt caagaatcag     4020

cagttttaga atttcagata gtacttgctc agaagtacat gctactcaag atattaagag     4080

ataacaagat ctgtagatct gctattgaat cagaatctgt gtacttgaac aaatgtgtga     4140

atctcaaata tctcaaagca aaagaaaaag tgttctagag tgttgttgct tttttaaaaa     4200

aagcgctgaa gttagaccaa ggtatacagt tttgttctaa cagacattta ggttaattgt     4260

aaagataagg aatgcattat gggtcaaaaa tcaaacattc ctctcatgtt atgtatattt     4320

tgttcctgtt atattggctt tattttcaaa attgtagttt gtagtattag tttcctttta     4380

ttggtattct tgcatatact attcattcaa taaatgactt atgactttca taaaaaaaaa     4440

aa                                                                    4442


<210>  1797
<211>  3353
<212>  DNA
<213>  homo sapiens

<400>  1797
gcggcggcgg cgcgggacgc gtcacatccc cttgaccctc caatcacctc gggctcccat       60

ttgattggaa ggcggcaaag gctttaatct cccccttggt gcagctgctt ttgaagtgag      120

tttcctcgcc agagccccgg ctggacacgc agcggctcgc atcgcagagc gcagcgccgg      180

cgcggggccg cgagaacgca gcgcagggga gcagcccgag gcggacaccg cgagccgccc      240

ggcactcccg cagtccagcc ggctcctcta gcccggccac ggctccgctg cgggccaccc      300

aggattactc gcgtctggct ccaggcgccg agaaggcgcg ctgggcgccc gtggccgccg      360

cgccagctcc tcctcctccc gctgctcctg ctcccggggc gagcgcgcag ccccgagccc      420

gccccgcgcc tcccggagcc ctcccccccg ctgctcccat gcgcgcgggt gggtcatgag      480

cacagcgccc tcgctttctg ccctaagaag cagtaagcac agcggcggcg gcggcggcgg      540

aggcggaggc ggcggtgcag accctgcctg gaccagcgcg ctctctggaa atagctccgg      600

ccccggccca ggctcgtccc cggccggcag caccaagcct tttgtgcacg ccgtgccccc      660

ctctgacccc ctgcgccagg ccaaccgcct gccaatcaag gtgctgaaga tgctgacggc      720

acgaactggc cacattttgc accccgagta cctgcagccc ctgccttcca cgccggtcag      780

ccccatcgag ctcgatgcca agaagagccc gctggcgctg ttggcgcaaa catgttcgca      840

gatcgggaag cccgacccct cgccctcctc caaactctcc tcggttgcct ccaacggggg      900

cggcgcgggc ggtgccggcg gcggtgctgc gggcgacaag gacaccaaat cgggccccct      960

gaagctgagc gacatcggcg tggaggacaa gtcgagtttc aagccgtact ccaaacccgg     1020

ctcggataag aaggagccgg gaggcggcgg tggaggcggt ggcggtggcg ggggcggcgg     1080

cgggggtgtt tcgtcggaga agtcgggatt ccgggtaccg agcgccacct gccagccatt     1140

cacgcccagg acaggcagcc cgagctccag cgcctcggcc tgctcgccgg gaggtatgct     1200

gtcctcggcc gggggtgccc cggagggcaa ggacgacaag aaagacaccg acgtgggcgg     1260

cggtggcaag ggcaccgggg gcgcctcggc cgaaggggga cccacggggc tggcacacgg     1320

ccggattagc tgcggcggcg ggattaatgt ggatgtgaac cagcatccgg atgggggccc     1380

gggaggcaag gctctgggct cggactgcgg cggttcatcg ggctccagct ccggctccgg     1440

ccccagcgcg cccacctcct cctcagtgtt gggctctggg ctggtggctc ccgtgtcacc     1500

ctacaagccg ggccagacag tgttccctct gcctcccgcg ggtatgacct acccaggcag     1560

cctggccggg gcctacgccg gctacccgcc ccagttcctg ccacacggcg tggcacttga     1620

ccccaccaag ccgggcagcc tggtgggggc gcagctggcg gcggccgcgg ccgggtctct     1680

gggctgcagt aagccggccg gctccagccc tttggccgga gcgtctccgc cgtccgtgat     1740

gacagccagt ttgtgccggg acccttactg cctcagctac cactgcgcta gccacctggc     1800

aggggcggcg gccgccagcg cttcttgcgc acatgatccg gctgctgcgg ctgcggcgct     1860

gaagtccgga tacccgctgg tgtaccccac gcacccgctg cacggtgtgc actcctcgct     1920

aacggccgcc gcggctgctg gcgccacacc gccctccctg gccggccacc ccctctaccc     1980

ctacggcttt atgctcccta acgacccact cccccacatc tgcaactggg tgtcggccaa     2040

cgggccgtgc gacaagcgct tcgccacgtc cgaagagctg ctgagccact tgcggaccca     2100

tacggcattt cccgggacag acaaactgct gtcgggctac cccagctcgt cgtctctggc     2160

cagcgctgcc gcggccgcca tggcttgcca catgcacatc cccacctcgg gcgcaccggg     2220

cagccctggg acgctggcgc tgcgcagccc ccaccacgcg ctgggactca gcagccgcta     2280

ccacccctac tccaagagcc cgcttcccac gcctggcgcc cccgtgccgg tgcccgccgc     2340

caccggaccg tactactccc cctacgccct ctacggacag agactgacca ccgcctcggc     2400

gctggggtat cagtgagggc ggccgggagg gcgagcgagg gagaggaggg agagggggag     2460

gggaggagtc cagggagagg cgggatcacg gcccaggctg ctgacacccg cgcgtgggga     2520

ggactcgggc cacgaaagga aagaaatgta taccgtatct atctacccga cagcagcgac     2580

cgagacccgg tgggacactc cccttctccc cactttcacc tccccaccca aactttataa     2640

aagttgaaaa aatatcattt gactttttat agaaaaaaaa aggaaaaaat aattgagaaa     2700

gtgttcatct gaggactgca tcggtggaca ctggtattta tttatgttag ctccaagcgg     2760

accggtggtt caaaagtgca ttatttagtt tgagctctgt aggtaaaaag gaggtgggaa     2820

aaattttaaa acttgagggt aaaaatgtgg aaaacaaacc ctcccatccc ttgtagatta     2880

taaataaaag caaaaccgcc acagaactag aggtcttctc tttaatgtta ctttaaaatt     2940

gctatgattg tattgtacgt tatttaatgt ctgattgaaa cacaaattta catgcatgtt     3000

tgttacaaaa aaaatgaaaa aaaaagtcac aatttgtcag ctctgatttc aaattgcaat     3060

tatttttaag gtgtatacca tcgaagagaa tgggtatttt tttgtatgta ttctggaaga     3120

aaacaacaaa aaaaaaaaga aaaagaaaaa attctattcc aaaacctcat ttgccttatt     3180

ttgttcttta aaaggaacac ttaactattt ttaattttta agtccacccg ctgagaaggg     3240

gacaaggttt acgtcatgta ctaaaataat agacaatgta tcgctttaaa gattaaaatt     3300

ccgtatattt gatgtattaa agggttttac ttcttaaaaa aaaaaaaaaa aaa            3353


<210>  1798
<211>  8313
<212>  DNA
<213>  homo sapiens

<400>  1798
attgaagtga atcatcagta taagtagcga gctgggcgca ttccttctca gttgtgttaa       60

aacttgctgg tattcccccg gtatcagcag aggtgtgtac gggcactgct ttaaaactgg      120

gaaggaggaa gacgaggcca gggagccgga gggtcaccaa ggtagatttc cagcagcgct      180

agtccagctg aacactttcc agccttgttt ttcagcagct ttgaggaaaa gtatagtgat      240

ccgtatgtga aactttcatt gtacgtagcg gatgagaata gagaacttgc tttggtccag      300

acaaaaacaa ttaaaaagac actgaaccca aaatggaatg aagaatttta tttcagggta      360

aacccatcta atcacagact cctatttgaa gtatttgacg aaaatagact gacacgagac      420

gacttcctgg gccaggtgga cgtgcccctt agtcaccttc cgacagaaga tccaaccatg      480

gagcgaccct atacatttaa ggactttctc ctcagaccaa gaagtcataa gtctcgagtt      540

aagggatttt tgcgattgaa aatggcctat atgccaaaaa atggaggtca agatgaagaa      600

aacagtgacc agagggatga catggagcat ggatgggaag ttgttgactc aaatgactcg      660

gcttctcagc accaagagga acttcctcct cctcctctgc ctcccgggtg ggaagaaaaa      720

gtggacaatt taggccgaac ttactatgtc aaccacaaca accggaccac tcagtggcac      780

agaccaagcc tgatggacgt gtcctcggag tcggacaata acatcagaca gatcaaccag      840

gaggcagcac accggcgctt ccgctcccgc aggcacatca gcgaagactt ggagcccgag      900

ccctcggagg gcggggatgt ccccgagcct tgggagacca tttcagagga agtgaatatc      960

gctggagact ctctcggtct ggctctgccc ccaccaccgg cctccccagg atctcggacc     1020

agccctcagg agctgtcaga ggaactaagc agaaggcttc agatcactcc agactccaat     1080

ggggaacagt tcagctcttt gattcaaaga gaaccctcct caaggttgag gtcatgcagt     1140

gtcaccgacg cagttgcaga acagggccat ctaccaccgc ccagtgcccc agctgggaga     1200

gcgcgttcat caactgtcac gggtggtgag gaaccaacgc catcagtggc ctatgtacat     1260

accacgccgg gtctgccttc aggctgggaa gaaagaaaag atgctaaggg gcgcacatac     1320

tatgtcaatc ataacaatcg aaccacaact tggactcgac ctatcatgca gcttgcagaa     1380

gatggtgcgt ccggatcagc cacaaacagt aacaaccatc taatcgagcc tcagatccgc     1440

cggcctcgta gcctcagctc gccaacagta actttatctg ccccgctgga gggtgccaag     1500

gactcacccg tacgtcgggc tgtgaaagac accctttcca acccacagtc cccacagcca     1560

tcaccttaca actcccccaa accacaacac aaagtcacac agagcttctt gccacccggc     1620

tgggaaatga ggatagcgcc aaacggccgg cccttcttca ttgatcataa cacaaagact     1680

acaacctggg aagatccacg tttgaaattt ccagtacata tgcggtcaaa gacatcttta     1740

aaccccaatg accttggccc ccttcctcct ggctgggaag aaagaattca cttggatggc     1800

cgaacgtttt atattgatca taatagcaaa attactcagt gggaagaccc aagactgcag     1860

aacccagcta ttactggtcc ggctgtccct tactccagag aatttaagca gaaatatgac     1920

tacttcagga agaaattaaa gaaacctgct gatatcccca ataggtttga aatgaaactt     1980

cacagaaata acatatttga agagtcctat cggagaatta tgtccgtgaa aagaccagat     2040

gtcctaaaag ctagactgtg gattgagttt gaatcagaga aaggtcttga ctatgggggt     2100

gtggccagag aatggttctt cttactgtcc aaagagatgt tcaaccccta ctacggcctc     2160

tttgagtact ctgccacgga caactacacc cttcagatca accctaattc aggcctctgt     2220

aatgaggatc atttgtccta cttcactttt attggaagag ttgctggtct ggccgtattt     2280

catgggaagc tcttagatgg tttcttcatt agaccatttt acaagatgat gttgggaaag     2340

cagataaccc tgaatgacat ggaatctgtg gatagtgaat attacaactc tttgaaatgg     2400

atcctggaga atgaccctac tgagctggac ctcatgttct gcatagacga agaaaacttt     2460

ggacagacat atcaagtgga tttgaagccc aatgggtcag aaataatggt cacaaatgaa     2520

aacaaaaggg aatatatcga cttagtcatc cagtggagat ttgtgaacag ggtccagaag     2580

cagatgaacg ccttcttgga gggattcaca gaactacttc ctattgattt gattaaaatt     2640

tttgatgaaa atgagctgga gttgctcatg tgcggcctcg gtgatgtgga tgtgaatgac     2700

tggagacagc attctattta caagaacggc tactgcccaa accaccccgt cattcagtgg     2760

ttctggaagg ctgtgctact catggacgcc gaaaagcgta tccggttact gcagtttgtc     2820

acagggacat cgcgagtacc tatgaatgga tttgccgaac tttatggttc caatggtcct     2880

cagctgttta caatagagca atggggcagt cctgagaaac tgcccagagc tcacacatgc     2940

tttaatcgcc ttgacttacc tccatatgaa acctttgaag atttacgaga gaaacttctc     3000

atggccgtgg aaaatgctca aggatttgaa ggggtggatt aagcaccctg tgcctcgggg     3060

gtggttgttc ttcaagcaag ttctgcttgc acttttgcat ttgcctaaca gacttttgca     3120

gaggcgatgg cagagagcag ctgcaggcat ggtccctgga gccgagcctt caccacgcac     3180

tcgtccaagt tcggatgcgg gaacctggtc ccagcttgag ttcctgcctt tcccaccaca     3240

aattatcaac tggttgatgt gtacactaat tacatttcag gaggacttaa tgctatttat     3300

gttgtgcctc tgcaggcaaa gcccttaata aatattttac atcctttcta atgacaatga     3360

atggaattaa tcactcaaca ggtatagtat tacgactcat gtttactttt taaaatgatt     3420

tagaccgatt ttcagatttt atttcgttat gattaaagat gtctcatgta cttggaaaag     3480

tgagcatttt tttttttttt gtatttcact ttcataccag gcttaatgtc aatgacattt     3540

ttatttttga agtactctga cacctccacc ctctacttta ttagaattgg aaggcaaatt     3600

tttgtccaaa aacctacaga caagtacttt gagagaattt ccaatataat attagacata     3660

atgataattt tttccatact cagaatgaaa aactggatat tacgtttttg ttttggggtt     3720

tttttgtaca aatttagcta atagctacag gctgagagaa ttgtaacata gcatgacaaa     3780

ttttgtgttg acttgaaagg aatcacacca ttattcctta gaagtaatta catgtgttct     3840

aacacatttg agacagggtt ggactcccat ttctcatccg agaaattact taacccttcc     3900

tggcgctgta cagtcatctt ttattctatt tcctctttgc tgtttgtagt agagacattt     3960

tgaatgaaac ttggcactgc ttgattcaaa actgtggaaa ccagatctgt ttagtctcct     4020

gtttgtatgc gtttgctaat ggtagctaaa taaccagttt ttgttgtaaa tgcaccaatt     4080

ctgaaggcac tttatgtact acatggaggt catatctggt tttgttttta tttttttatc     4140

atgaacatta aatgtgatga tgatttcttt tccctgcaca catctttccg gtgcaatatc     4200

tatcaattgt gaatctggct gctggtgtat aaaaacctgg atgtaaagct gagcctacag     4260

acctgtcctc accaactgtt ttgtgatttc tactcaacta caaagattta tttaatgtac     4320

tcttaatcta actgagtttt gttaccaatg acctgttgca tgcttcaata ccgtgtactg     4380

cctgagttgt gcctcttgtg tgctagatta aaagtgagac agagacttga cttgatcctc     4440

tgagctcaag ctattgagct ggtagtggca gaggactgag ggtacctgca cagtttgatt     4500

cttttccacg tgtaagtctc cattgcagaa ttgtcgtgct ttgagaaaac acctgaggca     4560

gtgtgggagt tgaacgaccc tgctgtcctt tttaacctgt gttgtcctag accctgtcgg     4620

ggcagtcagg ggacactaga gatttgatct catgcgagtc atcaatagga caaaaaagtt     4680

gtggtttggg gaggtctgtt tgttacataa aaaggacctt tcggtgtaag aaattgccgt     4740

ttttaccctg ccctggctgg catgtgagaa gccatggaag gttgtggttg taaatgagtt     4800

gtctaaaggg gtgcagaggc ctgaggtttc taaaagaagg tagatttcta cagagctgag     4860

tgttggttcc tttttcttat tggttgaaaa ttacctggta gtgatcagaa aacttagatg     4920

ctatgtaact aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaattc ccgctcatga     4980

gttttgacta ttggtgagat gttttccgct acagttaaca tgacaaatgt ctcagtggca     5040

aaaatcccct ttttgtaagc ccccatagtc tagaggcagt tttcttttta agaatcatgc     5100

cagagcctga gtcgagcagt atgctttctt ggtttttgag agtaattgtg taattgtaga     5160

gggagaaatc caattctaac ctaagaactg ggattcttct gtcatcttgt aaaccgtata     5220

ttgaaaaaaa cagaatgtca ctaaatgcat attaagtcaa gtattggaaa gtataaaaga     5280

aaaatcattc tgacaatttc taagccagaa gcaaacaaga attactgaaa tctaccccat     5340

gaatacttgg aaggcagtaa ttgtgagtga cacctcagtt catcaacccc ttaataatat     5400

cagcttaatt ttaatgacaa ctaaatatgc tgaagtgagg atttagtatt ttttaaaaaa     5460

gcaaaacaag gttcagtagt cctcagcaat tctccaagtt tctctctttg cctaaaatgg     5520

tcatagatct tgatttctct gaatcgtgat gaccacaccc agtcatcttc acagcataat     5580

tgcaggtggc agtaaagaga gtgtgctggg taaggagcag ttgctgggtc attccttggg     5640

ccccgacctg cccggggagt agccctgggg gagagagggc agtgttgcct atcccagagg     5700

tcccagcagt cacactgctc tgcaggccgg gctctcttta tagccagaga aatcacctta     5760

atgcagtctc tttagttgtc tgctgaagct gtagttatta tgggccactt acatgaggct     5820

gagaagtacg tgccggagct cacacactgc ctgttgcggt tctcttaaca tcagttatca     5880

cagctgcctg tgggtcccgg gtatttccat tcctgcccct tgttggcccg aggaaggatg     5940

tggaaagagc acctggtggg atgaaggtcc aacagcctgt gcctctccac tgctggccct     6000

ggagccggca gcagtgaggc attcattgtc tgtgttgcgg tgtattccca gcttcagtgc     6060

tcttttcctt tttgcctgaa atgtttatgc ttctctgcag ccagtcctct aacaaatctc     6120

aagaacaaag gtaagacact tggtttttgt ttccaggacc cttcagaagg tgacatcaga     6180

tattccctaa attcagacaa tgagggatac agagcgactt ggcatgtatt atttctccca     6240

tgtaaggaca aagggacaga ttattattgt tatttctgag acagagtctt gctctgtagc     6300

tcaggctgga gtgcagtggc tcaatctcag ctcaccacaa cctctgcctc ctggcttcaa     6360

gcgattcttc tgcctcagcc tccccgaata gttgggatta caggcaccca ccaccacgcc     6420

tggctaattt ttgtattttt agtagagatg gtttcaccat gctggccagg ctggtcttga     6480

actcctgacc tcaggtgatc ctcccgcctc agccttccaa agtgctggga ttacaagcat     6540

gagccaccgc acccggcctc acagtgacag attctgagaa acagcatgca aaacatttga     6600

accattttct acatctccca ttgttgcata gagagtgtgc accgctgcta tcttgccaga     6660

tccacactgg tcctcccgaa agccaggttc atacacagca actttttaat tattctaaca     6720

gttacccatt aacagtcgac tcctgtattt ctgagagtct tgtactcacc tctgaaattt     6780

aaaaacgtat aaagagagcc tgggttaatc agttctgcag cccctacgtg acactgtgct     6840

agttctcctt cttctgtctc ctccttaccc tggccctgca cccctgtact taagagggag     6900

aggtgggagg tgctgtctgg tatcatttgc tgcctcgcca gtagagggtg ccgctgtgca     6960

gggtaactgc ccgcctgctc ccttcctgac ctcccctgac cccgaagatc actacctctg     7020

tcattcaggc attggggtac atcctgataa gtcgtgtcag aactgccaat ttcaggactg     7080

agatgtgttt ttaaaaaaca aatccttata aactccactt tgtactttag attttaaaac     7140

tggggaaaaa tgtgatattc tttggaccac ttttttaatt tatataagcc ttaatgaaca     7200

gtgtctatac atttgcatac acacaccccc accccagagt gttctcagta tgtcagagaa     7260

agtgccacag cattaggacg ggagcttgga gaacgttttc tagaaaaggg ttagcttcct     7320

gttggcatga aattttccaa gcaaacctca ttaaacatct gttgtttgtt aaagatgttc     7380

cactgaaagc aacgcatgtt tcaaaggcac gtctttccgt tcgttggttt tctgtgtgta     7440

aggagtagca ttgctgttgg cgcctaacct cgcgtgcact gcattctcaa ccccgtacca     7500

gtgcatcatc agaagccttc ctcgtgacca taactctgtg tctgcagata tgtgttcccg     7560

tgtaagccag ttttcccctt ttactcagac tgatttcacc tagattgtca cggtttcctt     7620

catgttaact ttgcgtgact ttgttcttcc tttactactc tgtatgtaat atatatacat     7680

atatacgtac atatgctgtc caaatatatt tgtatatatt tgtatagcat ttttacacct     7740

ttattgagta atctggtttc gaaaggaggt gagagtttag tcccttctgc agttttctcc     7800

aagctgtgtc ctgtgaattt caacccttgg agcctaagaa aaccctagga agatgatgtt     7860

aatttgctgt catttcctaa ttcaggatct atcatcaaat gaaacatgaa aaaaacagtg     7920

acttttaagg tgaaaagagt ttcaagcatt ccaaataaat tatcaatgtt tcataacttt     7980

ttattataaa cccacctcct aataggaagc caagtactat ttgatacagt ggtaaaaacc     8040

aaactacctt gaattttttt aaggcaactt atgaataatg ctcattttca cagtcagaat     8100

agctttaaaa tatggttgaa tttgatacac acaggaagtt ttcttgaaga acaatccttt     8160

cgcttttctt ttttcttgag agatctaaag agaaactgta gattgttttc ctgacagcaa     8220

aagactaatg tgacaaaatg aagtcattgt aaagaagcga tgcaacttgt caaatattta     8280

ataaagaatt atggaagctg gaacattttc tac                                  8313


<210>  1799
<211>  3747
<212>  DNA
<213>  homo sapiens

<400>  1799
ccggcggccc gtgcgtcggc ggtggttggg tggtaagatg gcggctgtga gtctgcggct       60

cggcgacttg gtgtggggga aactcggccg atatcctcct tggccaggaa agattgttaa      120

tccaccaaag gacttgaaga aacctcgcgg aaagaaatgc ttctttgtga aattttttgg      180

aacagaagat catgcctgga tcaaagtgga acagctgaag ccatatcatg ctcataaaga      240

ggaaatgata aaaattaaca agggtaaacg attccagcaa gcggtagatg ctgtcgaaga      300

gttcctcagg agagccaaag ggaaagacca gacgtcatcc cacaattctt ctgatgacaa      360

gaatcgacgt aattccagtg aggagagaag taggccaaac tcaggtgatg agaagcgcaa      420

acttagcctg tctgaaggga aggtgaagaa gaacatggga gaaggaaaga agagggtgtc      480

ttcaggctct tcagagagag gctccaaatc ccctctgaaa agagcccaag agcaaagtcc      540

ccggaagcgg ggtcggcccc caaaggatga gaaggatctc accatcccgg agtctagtac      600

cgtgaagggg atgatggccg gaccgatggc cgcgtttaaa tggcagccaa ccgcaagcga      660

gcctgttaaa gatgcagatc ctcatttcca tcatttcctg ctaagccaaa cagagaagcc      720

agctgtctgt taccaggcaa tcacgaagaa gttgaaaata tgtgaagagg aaactggctc      780

cacctccatc caggcagctg acagcacagc cgtgaatggc agcatcacac ccacagacaa      840

aaagatagga tttttgggcc ttggtctcat gggaagtgga atcgtctcca acttgctaaa      900

aatgggtcac acagtgactg tctggaaccg cactgcagag aaatgtgatt tgttcatcca      960

ggagggggcc cgtctgggaa gaacccccgc tgaagtcgtc tcaacctgcg acatcacttt     1020

cgcctgcgtg tcggatccca aggcggccaa ggacctggtg ctgggcccca gtggtgtgct     1080

gcaagggatc cgccctggga agtgctacgt ggacatgtca acagtggacg ctgacaccgt     1140

cactgagctg gcccaggtga ttgtgtccag gggggggcgc tttctggaag cccccgtctc     1200

agggaatcag cagctgtcta atgacgggat gttggtgatc ttagcggctg gagacagggg     1260

cttatatgag gactgcagca gctgcttcca ggcgatgggg aagacctcct tcttcctagg     1320

tgaagtgggc aatgcagcca agatgatgct gatcgtgaac atggtccaag ggagcttcat     1380

ggccactatt gccgaggggc tgaccctggc ccaggtgaca ggccagtccc agcagacact     1440

cttggacatc ctcaatcagg gacagttggc cagcatcttc ctggaccaga agtgccaaaa     1500

tatcctgcaa ggaaacttta agcctgattt ctacctgaaa tacattcaga aggatctccg     1560

cttagccatt gcgctgggtg atgcggtcaa ccatccgact cccatggcag ctgcagcaaa     1620

tgaggtgtac aaaagagcca aggcgctgga ccagtctgac aacgatatgt ccgccgtgta     1680

ccgagcctac atacactaag ctgtcgacac cccgccctca cccctccaat cccccctctg     1740

accccctctt cctcacatgg ggtcgggggc ctgggagttc attctggacc agcccaccta     1800

tctccatttc cttttataca gactttgaga cttgccatca gcacagcaca cagcagcacc     1860

cttcccctga ggccggtggg gaggggacaa gtgtcagcag gattggcgtg tgggaaagct     1920

cttgagctgg gcactggccc cccggacgag gtggctgtgt gttcacacac acacacacac     1980

acacacacac acacacacac aggctctcgc cccaggatag aagctgccca gaaactgctg     2040

cctggctttt tttcttccga gcttgtctta tctcaaaccc cttccagtca aggaactaga     2100

atcagcaacg agagttggaa gccttcccac agcttccccc agagcgaaga ggctgtagtc     2160

atgtccccat cccccactgg attccctaca aggagaggcc ttgggcccag atgagccagt     2220

acagactcca gacagagggg cccttggggc cctccaacct caggtgatga gctgagaaag     2280

atgttcacgt ctaagcgtcc agtgtgcacc cagcgctcca tagacgcctt tgtgaactga     2340

aaagagactg gcagagtccc gagaagatgg ggccctggct ttccagggag tgcagcaagc     2400

agccggcctg caggtgagca tggaggcccg gccctcaccg cctcgaagcc atgccccaga     2460

tgccactgcc acagcgggcg ctcgctcctc cctaggctgt tttagtattt ggatttgcat     2520

tccatccctt gggagggagt cctcagggcc actagtgatg agccaagagg agtgggggtt     2580

gggggcgctc ctttctgttt ccgttaggcc acagactctt cacctggctc tgaagagcca     2640

ctcttacctc ggtcccctcc cagtggtccc accttctcca ccctgccctg ccaagtcccc     2700

tgcatgccca ccgctctcca tcctccctcc tctccctctt cctcccgtgg agacagtatt     2760

tctttctgtc tgtccctttg gcccagaccc agcctgacca acgatgagca tttcttaggc     2820

tcagctcttg atacggaaac gagtgtcttc actccagcca gcatcatggt cttcggtgct     2880

tcccgggccc ggggtctgtc gggagggaag agaactgggc ctgacctacc tgaactgact     2940

ggccctccga ggtgggtctg ggacatccta gaggccctac atttgtcctt ggatagggga     3000

ccgggggggg cttggaatgt tgcaaaaaaa aaagttaccc aagggatgtc agttttttat     3060

ccctctgcat gggttggatt ttccaaaatc ataatttgca gaaggaaggc cagcatttac     3120

gatgcaatat gtaattatat atagggtggc cacactaggg cggggtcctt cccccctcac     3180

agctttggcc cctttcagag attagaaact gggttagagg attgcagaag acgagtgggg     3240

ggagggcagg gaagatgcct gtcgggtttt tagcacagtt catttcactg ggattttgaa     3300

gcatttctgt ctgaacacaa agcctgttct agtcctggcg gaacacactg ggggtggggg     3360

cgggggaaga tgcggtaatg aaaccggtta gtcaattttg tcttaatatt gttgacaatt     3420

ctgtaaagtt cctttttatg aatatttctg tttaagctat ttcacctttc ttttgaaatc     3480

cttccctttt aaggagaaaa tgtgacactt gtgaaaaagc ttgtaagaaa gcccctccct     3540

tttttcttta aacctttaaa tgacaaatct aggtaattaa ggttgtgaat ttttattttt     3600

gctttgtttt taatgaacat ttgtctttca gaataggatt gtgtgataat gtttaaatgg     3660

caaaaacaaa acatgatttt gtgcaattaa caaagctact gcaagaaaaa taaaacactt     3720

cttggtaaca caaaaaaaaa aaaaaaa                                         3747


<210>  1800
<211>  3747
<212>  DNA
<213>  homo sapiens

<400>  1800
ccggcggccc gtgcgtcggc ggtggttggg tggtaagatg gcggctgtga gtctgcggct       60

cggcgacttg gtgtggggga aactcggccg atatcctcct tggccaggaa agattgttaa      120

tccaccaaag gacttgaaga aacctcgcgg aaagaaatgc ttctttgtga aattttttgg      180

aacagaagat catgcctgga tcaaagtgga acagctgaag ccatatcatg ctcataaaga      240

ggaaatgata aaaattaaca agggtaaacg attccagcaa gcggtagatg ctgtcgaaga      300

gttcctcagg agagccaaag ggaaagacca gacgtcatcc cacaattctt ctgatgacaa      360

gaatcgacgt aattccagtg aggagagaag taggccaaac tcaggtgatg agaagcgcaa      420

acttagcctg tctgaaggga aggtgaagaa gaacatggga gaaggaaaga agagggtgtc      480

ttcaggctct tcagagagag gctccaaatc ccctctgaaa agagcccaag agcaaagtcc      540

ccggaagcgg ggtcggcccc caaaggatga gaaggatctc accatcccgg agtctagtac      600

cgtgaagggg atgatggccg gaccgatggc cgcgtttaaa tggcagccaa ccgcaagcga      660

gcctgttaaa gatgcagatc ctcatttcca tcatttcctg ctaagccaaa cagagaagcc      720

agctgtctgt taccaggcaa tcacgaagaa gttgaaaata tgtgaagagg aaactggctc      780

cacctccatc caggcagctg acagcacagc cgtgaatggc agcatcacac ccacagacaa      840

aaagatagga tttttgggcc ttggtctcat gggaagtgga atcgtctcca acttgctaaa      900

aatgggtcac acagtgactg tctggaaccg cactgcagag aaatgtgatt tgttcatcca      960

ggagggggcc cgtctgggaa gaacccccgc tgaagtcgtc tcaacctgcg acatcacttt     1020

cgcctgcgtg tcggatccca aggcggccaa ggacctggtg ctgggcccca gtggtgtgct     1080

gcaagggatc cgccctggga agtgctacgt ggacatgtca acagtggacg ctgacaccgt     1140

cactgagctg gcccaggtga ttgtgtccag gggggggcgc tttctggaag cccccgtctc     1200

agggaatcag cagctgtcta atgacgggat gttggtgatc ttagcggctg gagacagggg     1260

cttatatgag gactgcagca gctgcttcca ggcgatgggg aagacctcct tcttcctagg     1320

tgaagtgggc aatgcagcca agatgatgct gatcgtgaac atggtccaag ggagcttcat     1380

ggccactatt gccgaggggc tgaccctggc ccaggtgaca ggccagtccc agcagacact     1440

cttggacatc ctcaatcagg gacagttggc cagcatcttc ctggaccaga agtgccaaaa     1500

tatcctgcaa ggaaacttta agcctgattt ctacctgaaa tacattcaga aggatctccg     1560

cttagccatt gcgctgggtg atgcggtcaa ccatccgact cccatggcag ctgcagcaaa     1620

tgaggtgtac aaaagagcca aggcgctgga ccagtctgac aacgatatgt ccgccgtgta     1680

ccgagcctac atacactaag ctgtcgacac cccgccctca cccctccaat cccccctctg     1740

accccctctt cctcacatgg ggtcgggggc ctgggagttc attctggacc agcccaccta     1800

tctccatttc cttttataca gactttgaga cttgccatca gcacagcaca cagcagcacc     1860

cttcccctga ggccggtggg gaggggacaa gtgtcagcag gattggcgtg tgggaaagct     1920

cttgagctgg gcactggccc cccggacgag gtggctgtgt gttcacacac acacacacac     1980

acacacacac acacacacac aggctctcgc cccaggatag aagctgccca gaaactgctg     2040

cctggctttt tttcttccga gcttgtctta tctcaaaccc cttccagtca aggaactaga     2100

atcagcaacg agagttggaa gccttcccac agcttccccc agagcgaaga ggctgtagtc     2160

atgtccccat cccccactgg attccctaca aggagaggcc ttgggcccag atgagccagt     2220

acagactcca gacagagggg cccttggggc cctccaacct caggtgatga gctgagaaag     2280

atgttcacgt ctaagcgtcc agtgtgcacc cagcgctcca tagacgcctt tgtgaactga     2340

aaagagactg gcagagtccc gagaagatgg ggccctggct ttccagggag tgcagcaagc     2400

agccggcctg caggtgagca tggaggcccg gccctcaccg cctcgaagcc atgccccaga     2460

tgccactgcc acagcgggcg ctcgctcctc cctaggctgt tttagtattt ggatttgcat     2520

tccatccctt gggagggagt cctcagggcc actagtgatg agccaagagg agtgggggtt     2580

gggggcgctc ctttctgttt ccgttaggcc acagactctt cacctggctc tgaagagcca     2640

ctcttacctc ggtcccctcc cagtggtccc accttctcca ccctgccctg ccaagtcccc     2700

tgcatgccca ccgctctcca tcctccctcc tctccctctt cctcccgtgg agacagtatt     2760

tctttctgtc tgtccctttg gcccagaccc agcctgacca acgatgagca tttcttaggc     2820

tcagctcttg atacggaaac gagtgtcttc actccagcca gcatcatggt cttcggtgct     2880

tcccgggccc ggggtctgtc gggagggaag agaactgggc ctgacctacc tgaactgact     2940

ggccctccga ggtgggtctg ggacatccta gaggccctac atttgtcctt ggatagggga     3000

ccgggggggg cttggaatgt tgcaaaaaaa aaagttaccc aagggatgtc agttttttat     3060

ccctctgcat gggttggatt ttccaaaatc ataatttgca gaaggaaggc cagcatttac     3120

gatgcaatat gtaattatat atagggtggc cacactaggg cggggtcctt cccccctcac     3180

agctttggcc cctttcagag attagaaact gggttagagg attgcagaag acgagtgggg     3240

ggagggcagg gaagatgcct gtcgggtttt tagcacagtt catttcactg ggattttgaa     3300

gcatttctgt ctgaacacaa agcctgttct agtcctggcg gaacacactg ggggtggggg     3360

cgggggaaga tgcggtaatg aaaccggtta gtcaattttg tcttaatatt gttgacaatt     3420

ctgtaaagtt cctttttatg aatatttctg tttaagctat ttcacctttc ttttgaaatc     3480

cttccctttt aaggagaaaa tgtgacactt gtgaaaaagc ttgtaagaaa gcccctccct     3540

tttttcttta aacctttaaa tgacaaatct aggtaattaa ggttgtgaat ttttattttt     3600

gctttgtttt taatgaacat ttgtctttca gaataggatt gtgtgataat gtttaaatgg     3660

caaaaacaaa acatgatttt gtgcaattaa caaagctact gcaagaaaaa taaaacactt     3720

cttggtaaca caaaaaaaaa aaaaaaa                                         3747


<210>  1801
<211>  3745
<212>  DNA
<213>  homo sapiens

<400>  1801
ccgagttcag tcatactgca ccagctgagc aatgcatgga gtggacctgt aggcgacttg       60

catcgtcttc aacatgaaga tagccacagt gtcagtgctt ctgcccttgg ctctttgcct      120

catacaagat gctgccagta agaatgaaga tcaggaaatg tgccatgaat ttcaggcatt      180

tatgaaaaat ggaaaactgt tctgtcccca ggataagaaa ttttttcaaa gtcttgatgg      240

aataatgttc atcaataaat gtgccacgtg caaaatgata ctggaaaaag aagcaaaatc      300

acagaagagg gccaggcatt tagcaagagc tcccaaggct actgccccaa cagagctgaa      360

ttgtgatgat tttaaaaaag gagaaagaga tggggatttt atctgtcctg attattatga      420

agctgtttgt ggcacagatg ggaaaacata tgacaacaga tgtgcactgt gtgctgagaa      480

tgcgaaaacc gggtcccaaa ttggtgtaaa aagtgaaggg gaatgtaaga gcagtaatcc      540

agagcaggat gtatgcagtg cttttcggcc ctttgttaga gatggaagac ttggatgcac      600

aagggaaaat gatcctgttc ttggtcctga tgggaagacg catggcaata agtgtgcaat      660

gtgtgctgag ctgtttttaa aagaagctga aaatgccaag cgagagggtg aaactagaat      720

tcgacgaaat gctgaaaagg atttttgcaa ggaatatgaa aaacaagtga gaaatggaag      780

gcttttttgt acacgggaga gtgatccagt ccgtggccct gacggcagga tgcatggcaa      840

caaatgtgcc ctgtgtgctg aaattttcaa gcagcgtttt tcagaggaaa acagtaaaac      900

agatcaaaat ttgggaaaag ctgaagaaaa aactaaagtt aaaagagaaa ttgtgaaact      960

ctgcagtcaa tatcaaaatc aggcaaagaa tggaatactt ttctgtacca gagaaaatga     1020

ccctattcgt ggtccagatg ggaaaatgca tggcaacttg tgttccatgt gtcaagccta     1080

cttccaagca gaaaatgaag aaaagaaaaa ggctgaagca cgagctagaa acaaaagaga     1140

atctggaaaa gcaacctcat atgcagagct ttgcagtgaa tatcgaaagc ttgtgaggaa     1200

cggaaaactt gcttgcacca gagagaacga tcctatccag ggcccagatg ggaaagtgca     1260

tggcaacacc tgctccatgt gtgaggtctt cttccaagca gaagaagaag aaaagaaaaa     1320

gaaggaaggt aaatcaagaa acaaaagaca atctaagagt acagcttcct ttgaggagtt     1380

gtgtagtgaa taccgcaaat ccaggaaaaa cggacggctt ttttgcacca gagagaatga     1440

ccccatccag ggcccagatg gaaaaatgca tggcaacacc tgctccatgt gtgaggcctt     1500

ctttcaacaa gaagaaagag caagagcaaa ggctaaaaga gaagctgcaa aggaaatctg     1560

cagtgaattt cgggaccaag tgaggaatgg aacacttata tgcaccaggg agcataatcc     1620

tgtccgtggc ccagatggca aaatgcatgg aaacaagtgt gccatgtgtg ccagtgtgtt     1680

caaacttgaa gaagaagaga agaaaaatga taaagaagaa aaagggaaag tcgaggctga     1740

aaaagttaag agagaagcag ttcaggagct gtgcagtgaa tatcgtcatt atgtgaggaa     1800

tggacgactc ccctgtacca gagagaatga tcctattgag ggtctagatg ggaaaatcca     1860

cggcaacacc tgctccatgt gtgaagcctt cttccagcaa gaagcaaaag aaaaagaaag     1920

agctgaaccc agagcaaaag tcaaaagaga agctgaaaag gagacatgcg atgaatttcg     1980

gagacttttg caaaatggaa aacttttctg cacaagagaa aatgatcctg tgcgtggccc     2040

agatggcaag acccatggca acaagtgtgc catgtgtaag gcagtcttcc agaaagaaaa     2100

tgaggaaaga aagaggaaag aagaggaaga tcagagaaat gctgcaggac atggttccag     2160

tggtggtgga ggaggaaaca ctcaggacga atgtgctgag tatcgggaac aaatgaaaaa     2220

tggaagactc agctgtactc gggagagtga tcctgtacgt gatgctgatg gcaaatcgta     2280

caacaatcag tgtaccatgt gtaaagcaaa attggaaaga gaagcagaga gaaaaaatga     2340

gtattctcgc tccagatcaa atgggactgg atcagaatca gggaaggata catgtgatga     2400

gtttagaagc caaatgaaaa atggaaaact catctgcact cgagaaagtg accctgtccg     2460

gggtccagat ggcaagacac atggcaataa gtgtactatg tgtaaggaaa aactggaaag     2520

ggaagcagct gaaaaaaaaa agaaagagga tgaagacagg agcaatacag gagaaaggag     2580

caatacagga gaaaggagca atgacaaaga ggatctgtgt cgtgaatttc gaagcatgca     2640

gagaaatgga aagcttatct gcaccagaga aaataaccct gttcgaggcc catatggcaa     2700

gatgcacatc aataaatgtg ctatgtgtca gagcatcttt gatcgagaag ctaatgaaag     2760

aaaaaagaaa gatgaagaga aatcaagtag caagccctca aataatgcaa aggaccagtg     2820

cagacaggtt cagaatgaag cggaggatgc aaaatttaga caacctgggc gttccttggc     2880

ctctgttgcc aggatgagta cagatgagtg cagtgaattt cgaaactata taaggaacaa     2940

tgaactcatc tgccctagag agaatgaccc agtgcacggt gctgatggaa agttctatac     3000

aaacaagtgc tacatgtgca gagctgtctt tctaacagaa gctttggaaa gggcaaagct     3060

tcaagaaaag ccatcccatg ttagagcttc tcaagaggaa gacagcccag actctttcag     3120

ttctctggat tctgagatgt gcaaagacta ccgagtattg cccaggatag gttatctttg     3180

tccaaaggat ttaaagcctg tctgtggtga cgatggccaa acctacaaca atccttgcat     3240

gctctgtcat gaaaacctga tacgccaaac aaatacacac atccgcagta cagggaagtg     3300

tgaggagagc agcaccccag gaaccaccgc agccagcatg cccccgtctg acgaatgaca     3360

ggaagattgt tgaaagccat gagggaaaaa ataaacccca gttctgaatc acctaccttc     3420

accatctgta tatacaaaga attcttcgga gcttgtctta tttgctatag aaaacaatac     3480

agagcttttg ggaatggact cactgatttt cagtcttttc catctctttc ctcctagact     3540

ctgtgatctg agggtataaa gacatctcca ccaagtctga gccctcaaaa tgtcctgatt     3600

acaatgctgt ctgtccaact gcctgttcaa taaaagtaaa ctcagcagaa caccctttct     3660

gggatttctt tgtcactatc tggataatag atatttgctt ttaaagaaac tgaataaact     3720

ctacccttta aaaaaaaaaa aaaaa                                           3745


<210>  1802
<211>  2274
<212>  DNA
<213>  homo sapiens

<400>  1802
gcagaactcg cacaagggac cttatttagg ttgcgcaggc gcccgctggc catttcgtct       60

tagccacgca gaagtcgcgt gtctagtttg tttcgacgcc ggaccgcgta agagacgatg      120

atgttgggca cggaaggtgg agagggattc gtggtgaagg tccggggctt gccctggtct      180

tgctcggccg atgaagtgca gaggtttttt tctgactgca aaattcaaaa tggggctcaa      240

ggtattcgtt tcatctacac cagagaaggc agaccaagtg gcgaggcttt tgttgaactt      300

gaatcagaag atgaagtcaa attggccctg aaaaaagaca gagaaactat gggacacaga      360

tatgttgaag tattcaagtc aaacaacgtt gaaatggatt gggtgttgaa gcatactggt      420

ccaaatagtc ctgacacggc caatgatggc tttgtacggc ttagaggact tccctttgga      480

tgtagcaagg aagaaattgt tcagttcttc tcagggttgg aaatcgtgcc aaatgggata      540

acattgccgg tggacttcca ggggaggagt acgggggagg ccttcgtgca gtttgcttca      600

caggaaatag ctgaaaaggc tctaaagaaa cacaaggaaa gaatagggca caggtatatt      660

gaaatcttta agagcagtag agctgaagtt agaactcatt atgatccacc acgaaagctt      720

atggccatgc agcggccagg tccttatgac agacctgggg ctggtagagg gtataacagc      780

attggcagag gagctggctt tgagaggatg aggcgtggtg cttatggtgg aggctatgga      840

ggctatgatg attacaatgg ctataatgat ggctatggat ttgggtcaga tagatttgga      900

agagacctca attactgttt ttcaggaatg tctgatcaca gatacgggga tggtggctct      960

actttccaga gcacaacagg acactgtgta cacatgcggg gattacctta cagagctact     1020

gagaatgaca tttataattt tttttcaccg ctcaaccctg tgagagtaca cattgaaatt     1080

ggtcctgatg gcagagtaac tggtgaagca gatgtcgagt tcgcaactca tgaagatgct     1140

gtggcagcta tgtcaaaaga caaagcaaat atgcaacaca gatatgtaga actcttcttg     1200

aattctacag caggagcaag cggtggtgct tacgaacaca gatatgtaga actcttcttg     1260

aattctacag caggagcaag cggtggtgct tatggtagcc aaatgatggg aggcatgggc     1320

ttgtcaaacc agtccagcta cgggggccca gccagccagc agctgagtgg gggttacgga     1380

ggcggctacg gtggccagag cagcatgagt ggatacgacc aagttttaca ggaaaactcc     1440

agtgattttc aatcaaacat tgcataggta accaaggagc agtgaacagc agctactaca     1500

gtagtggaag ccgtgcatct atgggcgtga acggaatggg agggttgtct agcatgtcca     1560

gtatgagtgg tggatgggga atgtaattga tcgatcctga tcactgactc ttggtcaacc     1620

tttttttttt tttttttttt ttctttaaga aaacttcagt ttaacagttt ctgcaataca     1680

agcttgtgat ttatgcttac tctaagtgga aatcaggatt gttatgaaga cttaaggccc     1740

agtatttttg aatacaatac tcatctagga tgtaacagtg aagctgagta aactataact     1800

gttaaactta agttccagct tttctcaagt tagttatagg atgtacttaa gcagtaagcg     1860

tatttaggta aaagcagttg aattatgtta aatgttgccc tttgccacgt taaattgaac     1920

actgttttgg atgcatgttg aaagacatgc ttttattttt ttgtaaaaca atataggagc     1980

tgtgtctact attaaaagtg aaacattttg gcatgtttgt taattctagt ttcatttaat     2040

aacctgtaag gcacgtaagt ttaagctttt ttttttttta agttaatggg aaaaatttga     2100

gacgcaatac caatacttag gattttggtc ttggtgtttg tatgaaattc tgaggccttg     2160

atttaaatct ttcattgtat tgtgatttcc ttttaggtat attgcgctaa gtgaaacttg     2220

tcaaataaat cctcctttta aaaactgcaa aaaaaaaaaa aaaaaaaaaa aaaa           2274


<210>  1803
<211>  881
<212>  DNA
<213>  homo sapiens

<400>  1803
gagtcctctc agccgcccga gggcgctgcg ctgagcctta cactctatga ttgctcctac       60

cgactcccat gaggaagtgc gatcgggaac ctcctatata cttccgtttg cctcgcggtt      120

tctttctttc cgcgccgata gcgctcacgc aagcatggtt aacgtcccta aaacccgccg      180

gactttctgt aagaagtgtg gcaagcacca accccataaa gtgacacagt acaagaaggg      240

caaggattct ctgtacgccc agggaaagcg gcgttatgac aggaagcaga gtggctatgg      300

tgggcaaact aagccgattt tccggaaaaa ggctaaaact acaaagaaga ttgtgctaag      360

gcttgagtgc gttgagccca actgcagatc taagagaatg ctggctatta aaagatgcaa      420

gcattttgaa ctgggaggag ataagaagag aaagggccaa gtgatccagt tctaagtgtc      480

atcttttatt atgaagacaa taaaatcttg agtttatgtt cacttcattt gtttgctgtt      540

catcttttgg gagggaataa gctagagcca tcaatacaat tccgcttgtg gggaaattta      600

tgcctcttac tggtactact tgttttgcat tgaagctgac tggttgagtt cacatcatat      660

gttgcaattt tctaatttgg cacttcaatc actaggggcc ttatgaggca gtttgtcatt      720

atgcaatggt tattggttat catgtgagta gacacatttc aggctaatag ggagaagtca      780

gtaacacatt catagtgaat atgagatgtc tttgctaaga gttaagtgtc agatctttgt      840

tataacagtt aatttaataa agaattttgg cattgttctt c                          881


<210>  1804
<211>  2798
<212>  DNA
<213>  homo sapiens

<400>  1804
gctgagcgcg gagccgcccg gtgattggtg ggggcggaag ggggccgggc gccagcgctg       60

ccttttctcc tgccgggtag tttcgctttc ctgcgcagag tctgcggagg ggctcggctg      120

caccgggggg atcgcgcctg gcagacccca gaccgagcag aggcgaccca gcgcgctcgg      180

gagaggctgc accgccgcgc ccccgcctag cccttccgga tcctgcgcgc agaaaagttt      240

catttgctgt atgccatcct cgagagctgt ctaggttaac gttcgcactc tgtgtatata      300

acctcgacag tcttggcacc taacgtgctg tgcgtagctg ctcctttggt tgaatcccca      360

ggcccttgtt ggggcacaag gtggcaggat gtctcagtgg tacgaacttc agcagcttga      420

ctcaaaattc ctggagcagg ttcaccagct ttatgatgac agttttccca tggaaatcag      480

acagtacctg gcacagtggt tagaaaagca agactgggag cacgctgcca atgatgtttc      540

atttgccacc atccgttttc atgacctcct gtcacagctg gatgatcaat atagtcgctt      600

ttctttggag aataacttct tgctacagca taacataagg aaaagcaagc gtaatcttca      660

ggataatttt caggaagacc caatccagat gtctatgatc atttacagct gtctgaagga      720

agaaaggaaa attctggaaa acgcccagag atttaatcag gctcagtcgg ggaatattca      780

gagcacagtg atgttagaca aacagaaaga gcttgacagt aaagtcagaa atgtgaagga      840

caaggttatg tgtatagagc atgaaatcaa gagcctggaa gatttacaag atgaatatga      900

cttcaaatgc aaaaccttgc agaacagaga acacgagacc aatggtgtgg caaagagtga      960

tcagaaacaa gaacagctgt tactcaagaa gatgtattta atgcttgaca ataagagaaa     1020

ggaagtagtt cacaaaataa tagagttgct gaatgtcact gaacttaccc agaatgccct     1080

gattaatgat gaactagtgg agtggaagcg gagacagcag agcgcctgta ttggggggcc     1140

gcccaatgct tgcttggatc agctgcagaa ctggttcact atagttgcgg agagtctgca     1200

gcaagttcgg cagcagctta aaaagttgga ggaattggaa cagaaataca cctacgaaca     1260

tgaccctatc acaaaaaaca aacaagtgtt atgggaccgc accttcagtc ttttccagca     1320

gctcattcag agctcgtttg tggtggaaag acagccctgc atgccaacgc accctcagag     1380

gccgctggtc ttgaagacag gggtccagtt cactgtgaag ttgagactgt tggtgaaatt     1440

gcaagagctg aattataatt tgaaagtcaa agtcttattt gataaagatg tgaatgagag     1500

aaatacagta aaaggattta ggaagttcaa cattttgggc acgcacacaa aagtgatgaa     1560

catggaggag tccaccaatg gcagtctggc ggctgaattt cggcacctgc aattgaaaga     1620

acagaaaaat gctggcacca gaacgaatga gggtcctctc atcgttactg aagagcttca     1680

ctcccttagt tttgaaaccc aattgtgcca gcctggtttg gtaattgacc tcgagacgac     1740

ctctctgccc gttgtggtga tctccaacgt cagccagctc ccgagcggtt gggcctccat     1800

cctttggtac aacatgctgg tggcggaacc caggaatctg tccttcttcc tgactccacc     1860

atgtgcacga tgggctcagc tttcagaagt gctgagttgg cagttttctt ctgtcaccaa     1920

aagaggtctc aatgtggacc agctgaacat gttgggagag aagcttcttg gtcctaacgc     1980

cagccccgat ggtctcattc cgtggacgag gttttgtaag gaaaatataa atgataaaaa     2040

ttttcccttc tggctttgga ttgaaagcat cctagaactc attaaaaaac acctgctccc     2100

tctctggaat gatgggtgca tcatgggctt catcagcaag gagcgagagc gtgccctgtt     2160

gaaggaccag cagccgggga ccttcctgct gcggttcagt gagagctccc gggaaggggc     2220

catcacattc acatgggtgg agcggtccca gaacggaggc gaacctgact tccatgcggt     2280

tgaaccctac acgaagaaag aactttctgc tgttactttc cctgacatca ttcgcaatta     2340

caaagtcatg gctgctgaga atattcctga gaatcccctg aagtatctgt atccaaatat     2400

tgacaaagac catgcctttg gaaagtatta ctccaggcca aaggaagcac cagagccaat     2460

ggaacttgat ggccctaaag gaactggata tatcaagact gagttgattt ctgtgtctga     2520

agtgtaagtg aacacagaag agtgacatgt ttacaaacct caagccagcc ttgctcctgg     2580

ctggggcctg ttgaagatgc ttgtatttta cttttccatt gtaattgcta tcgccatcac     2640

agctgaactt gttgagatcc ccgtgttact gcctatcagc attttactac tttaaaaaaa     2700

aaaaaaaagc caaaaaccaa atttgtattt aaggtatata aattttccca aaactgatac     2760

cctttgaaaa agtataaata aaatgagcaa aagttgat                             2798


<210>  1805
<211>  4240
<212>  DNA
<213>  homo sapiens

<400>  1805
ggttgggctc gcggcgctgt gattggtctg cccggactcc gcctccagcg catgtcatta       60

gcatctcatt agctgtccgc tcgggctccg gaggcagcca acgccgccag tctgaggcag      120

gtgcccgaca tggcgagtgt agtgctgccg agcggatccc agtgtgcggc ggcagcggcg      180

gcggcggcgc ctcccgggct ccggctccgg cttctgctgt tgctcttctc cgccgcggca      240

ctgatcccca caggtgatgg gcagaatctg tttacgaaag acgtgacagt gatcgaggga      300

gaggttgcga ccatcagttg ccaagtcaat aagagtgacg actctgtgat tcagctactg      360

aatcccaaca ggcagaccat ttatttcagg gacttcaggc ctttgaagga cagcaggttt      420

cagttgctga atttttctag cagtgaactc aaagtatcat tgacaaacgt ctcaatttct      480

gatgaaggaa gatacttttg ccagctctat accgatcccc cacaggaaag ttacaccacc      540

atcacagtcc tggtcccacc acgtaatctg atgatcgata tccagaaaga cactgcggtg      600

gaaggtgagg agattgaagt caactgcact gctatggcca gcaagccagc cacgactatc      660

aggtggttca aagggaacac agagctaaaa ggcaaatcgg aggtggaaga gtggtcagac      720

atgtacactg tgaccagtca gctgatgctg aaggtgcaca aggaggacga tggggtccca      780

gtgatctgcc aggtggagca ccctgcggtc actggaaacc tgcagaccca gcggtatcta      840

gaagtacagt ataagcctca agtgcacatt cagatgactt atcctctaca aggcttaacc      900

cgggaagggg acgcgcttga gttaacatgt gaagccatcg ggaagcccca gcctgtgatg      960

gtaacttggg tgagagtcga tgatgaaatg cctcaacacg ccgtactgtc tgggcccaac     1020

ctgttcatca ataacctaaa caaaacagat aatggtacat accgctgtga agcttcaaac     1080

atagtgggga aagctcactc ggattatatg ctgtatgtat acgattcccg agcaggtgaa     1140

gaaggctcga tcagggcagt ggatcatgcc gtgatcggtg gcgtcgtggc ggtggtggtg     1200

ttcgccatgc tgtgcttgct catcattctg gggcgctatt ttgccagaca taaaggtaca     1260

tacttcactc atgaagccaa aggagccgat gacgcagcag acgcagacac agctataatc     1320

aatgcagaag gaggacagaa caactccgaa gaaaagaaag agtacttcat ctagatcagc     1380

ctttttgttt caatgaggtg tccaactggc cctatttaga tgataaagag acagtgatat     1440

tggaacttgc gagaaattcg tgtgtttttt tatgaatggg tggaaaggtg tgagactggg     1500

aaggcttggg atttgctgtg taaaaaaaaa aaaaatgttc tttggaaagt acactctgct     1560

gtttgacacc tcttttttcg tttgtttgtt tgtttaattt ttatttcttc ctaccaagtc     1620

aaacttggat acttggattt agtttcagta gattgcagaa aattctgtgc cttgtttttt     1680

gtttgtttgt tgcgttcctt tcttttcccc ctttgtgcac atttatttcc tccctctacc     1740

ccaatttcgg attttttcca aaatctccca ttttggaatt tgcctgctgg gattccttag     1800

actcttttcc ttcccttttc tgttctagtt ttttactttt gtttattttt atggtaactg     1860

ctttctgttc caaattcagt ttcataaaag gagaaccagc acagcttaga tttcatagtt     1920

cagaatttag tgtatccata atgcattctt ctctgttgtc gtaaagattt gggtgaacaa     1980

acaatgaaaa ctctttgctg ctgcccatgt ttcaaatact tagagcagtg aagactagaa     2040

aattagactg tgattcagaa aatgttctgt ttgctgtgga actacattac tgtacagggt     2100

tatctgcaag tgaggtgtgt cacaatgaga ttgaatttca ctgtctttaa ttctgtatct     2160

gtagacggct cagtatagat accctacgct gtccagaaag gtttggggca gaaaggactc     2220

ctcctttttc catgccctaa acagacctga caggtgaggt ctgttccttt tatataagtg     2280

gacaaatttt gagttgccac aggaggggaa gtagggaggg gggaaataca gttctgctct     2340

ggttgtttct gttccaaatg attccatcca cctttcccaa tcggccttac ttctcactaa     2400

tttgtaggaa aaagcaagtt cgtctgttgt gcgaatgact gaatgggaca gagttgattt     2460

tttttttttt ttcctttgtg cttagttagg aaggcagtag gatgtggcct gcatgtactg     2520

tatattacag atatttgtca tgctgggatt tccaactcga atctgtgtga aactttcatt     2580

ccttcagatt tggcttgaca aaggcaggag gtacaaaaga agggctggta ttgttctcac     2640

actggtctgc tgtcgctctc agttctcgat aggtcagagc agaggtggaa aaacagcatg     2700

tacggatttt cagttactta atcaaaactc aaatgtgagt gtttttatct ttttaccttt     2760

catacactag ccttggcctc tttcctcagc cttaagaacc atctgccaaa aattactgat     2820

cctcgcatga tggcagccat agtgcatagc tactaaaatc agtgaccttg aacatatctt     2880

agatggggag cctcgggaaa aggtagagga gtcacgttac catttacatg ttttaaagaa     2940

agaagtgtgg ggattttcac tgaaacgtct aggaaatcta gaagtagtcc tgaaggacag     3000

aaactaaact cttaccatat gtttggtaag actccagact ccagctaaca gtccctatgg     3060

aaagatggca tcaaaaaaga tagatctata tatatatata aatatatatt ctattacatt     3120

ttcagtgagt aattttggat tttgcaaggt gcatttttac tattgttaca ttatgtggaa     3180

aacttatgct gatttattta agggggaaaa agtgtcaact ctttgttatt tgaaaacatg     3240

tttatttttc ttgtctttat tttaaccttt gatagaacca ttgcaatatg ggggcctttt     3300

gggaacggac tggtatgtaa aagaaaatcc attatcgagc agcattttat ttacccctcc     3360

cctatcccta ggcacttaac caagacaaaa agccacaatg aacatccctt tttcaatgaa     3420

ttttataatc tgcagctcta ttccgagccc ttagcaccca ttccgaccat agtataatca     3480

tatcaaaggg tgagaatcat ttagcatgtt gttgaaaggt tttttttcag ttgttctttt     3540

tagaaaaaaa gaaaaacaaa aacaaaaaca aaaaaaaaaa atcacaccat tgctcacaga     3600

attggcatct catttttggg acctcccatc tttctgtttt gaaaagtgta cagtagtgca     3660

gtgttcctga tgtaacttta tggcttacaa tgttgacatg tctcaggttc atgtgttgcg     3720

attggtgttt tccgtctcag gtagattgca aagtgtaggc cccacacatt ggaaaaaata     3780

ataataaaac aaagcaaaaa caggaaatta tggattttag ttgtatattg gtttatgtat     3840

tttttcttaa gtatacagtg cactgtttga aatgtattgt tgagtattac tttgtacagg     3900

ttgatcactt tttttagagt gaagaaagaa caaacttgtt ttttgtgttt tttaaaggaa     3960

tataaaataa tgaaggatgt ataattgatg ccaaataagc ttgttcttta gtcacaccga     4020

cgtcttattt ttccctttag gccagttctg tttttaaggt gtacatggac aatgttacag     4080

tgtaagaaac tccatatcca tatgttccca ttcgcatttt gtattggttc atgtatacca     4140

tttttacaaa aaaaaaaaga aaaaaaagaa gtactataaa atatctgtct tcttaataaa     4200

aaaaaattaa tgttacaaag tgaaaaaaaa aaaaaaaaaa                           4240


<210>  1806
<211>  4324
<212>  DNA
<213>  homo sapiens

<400>  1806
ggttgggctc gcggcgctgt gattggtctg cccggactcc gcctccagcg catgtcatta       60

gcatctcatt agctgtccgc tcgggctccg gaggcagcca acgccgccag tctgaggcag      120

gtgcccgaca tggcgagtgt agtgctgccg agcggatccc agtgtgcggc ggcagcggcg      180

gcggcggcgc ctcccgggct ccggctccgg cttctgctgt tgctcttctc cgccgcggca      240

ctgatcccca caggtgatgg gcagaatctg tttacgaaag acgtgacagt gatcgaggga      300

gaggttgcga ccatcagttg ccaagtcaat aagagtgacg actctgtgat tcagctactg      360

aatcccaaca ggcagaccat ttatttcagg gacttcaggc ctttgaagga cagcaggttt      420

cagttgctga atttttctag cagtgaactc aaagtatcat tgacaaacgt ctcaatttct      480

gatgaaggaa gatacttttg ccagctctat accgatcccc cacaggaaag ttacaccacc      540

atcacagtcc tggtcccacc acgtaatctg atgatcgata tccagaaaga cactgcggtg      600

gaaggtgagg agattgaagt caactgcact gctatggcca gcaagccagc cacgactatc      660

aggtggttca aagggaacac agagctaaaa ggcaaatcgg aggtggaaga gtggtcagac      720

atgtacactg tgaccagtca gctgatgctg aaggtgcaca aggaggacga tggggtccca      780

gtgatctgcc aggtggagca ccctgcggtc actggaaacc tgcagaccca gcggtatcta      840

gaagtacagt ataagcctca agtgcacatt cagatgactt atcctctaca aggcttaacc      900

cgggaagggg acgcgcttga gttaacatgt gaagccatcg ggaagcccca gcctgtgatg      960

gtaacttggg tgagagtcga tgatgaaatg cctcaacacg ccgtactgtc tgggcccaac     1020

ctgttcatca ataacctaaa caaaacagat aatggtacat accgctgtga agcttcaaac     1080

atagtgggga aagctcactc ggattatatg ctgtatgtat acgatccccc cacaactatc     1140

cctcctccca caacaaccac caccaccacc accaccacca ccaccaccat ccttaccatc     1200

atcacagatt cccgagcagg tgaagaaggc tcgatcaggg cagtggatca tgccgtgatc     1260

ggtggcgtcg tggcggtggt ggtgttcgcc atgctgtgct tgctcatcat tctggggcgc     1320

tattttgcca gacataaagg tacatacttc actcatgaag ccaaaggagc cgatgacgca     1380

gcagacgcag acacagctat aatcaatgca gaaggaggac agaacaactc cgaagaaaag     1440

aaagagtact tcatctagat cagccttttt gtttcaatga ggtgtccaac tggccctatt     1500

tagatgataa agagacagtg atattggaac ttgcgagaaa ttcgtgtgtt tttttatgaa     1560

tgggtggaaa ggtgtgagac tgggaaggct tgggatttgc tgtgtaaaaa aaaaaaaaat     1620

gttctttgga aagtacactc tgctgtttga cacctctttt ttcgtttgtt tgtttgttta     1680

atttttattt cttcctacca agtcaaactt ggatacttgg atttagtttc agtagattgc     1740

agaaaattct gtgccttgtt ttttgtttgt ttgttgcgtt cctttctttt ccccctttgt     1800

gcacatttat ttcctccctc taccccaatt tcggattttt tccaaaatct cccattttgg     1860

aatttgcctg ctgggattcc ttagactctt ttccttccct tttctgttct agttttttac     1920

ttttgtttat ttttatggta actgctttct gttccaaatt cagtttcata aaaggagaac     1980

cagcacagct tagatttcat agttcagaat ttagtgtatc cataatgcat tcttctctgt     2040

tgtcgtaaag atttgggtga acaaacaatg aaaactcttt gctgctgccc atgtttcaaa     2100

tacttagagc agtgaagact agaaaattag actgtgattc agaaaatgtt ctgtttgctg     2160

tggaactaca ttactgtaca gggttatctg caagtgaggt gtgtcacaat gagattgaat     2220

ttcactgtct ttaattctgt atctgtagac ggctcagtat agatacccta cgctgtccag     2280

aaaggtttgg ggcagaaagg actcctcctt tttccatgcc ctaaacagac ctgacaggtg     2340

aggtctgttc cttttatata agtggacaaa ttttgagttg ccacaggagg ggaagtaggg     2400

aggggggaaa tacagttctg ctctggttgt ttctgttcca aatgattcca tccacctttc     2460

ccaatcggcc ttacttctca ctaatttgta ggaaaaagca agttcgtctg ttgtgcgaat     2520

gactgaatgg gacagagttg attttttttt ttttttcctt tgtgcttagt taggaaggca     2580

gtaggatgtg gcctgcatgt actgtatatt acagatattt gtcatgctgg gatttccaac     2640

tcgaatctgt gtgaaacttt cattccttca gatttggctt gacaaaggca ggaggtacaa     2700

aagaagggct ggtattgttc tcacactggt ctgctgtcgc tctcagttct cgataggtca     2760

gagcagaggt ggaaaaacag catgtacgga ttttcagtta cttaatcaaa actcaaatgt     2820

gagtgttttt atctttttac ctttcataca ctagccttgg cctctttcct cagccttaag     2880

aaccatctgc caaaaattac tgatcctcgc atgatggcag ccatagtgca tagctactaa     2940

aatcagtgac cttgaacata tcttagatgg ggagcctcgg gaaaaggtag aggagtcacg     3000

ttaccattta catgttttaa agaaagaagt gtggggattt tcactgaaac gtctaggaaa     3060

tctagaagta gtcctgaagg acagaaacta aactcttacc atatgtttgg taagactcca     3120

gactccagct aacagtccct atggaaagat ggcatcaaaa aagatagatc tatatatata     3180

tataaatata tattctatta cattttcagt gagtaatttt ggattttgca aggtgcattt     3240

ttactattgt tacattatgt ggaaaactta tgctgattta tttaaggggg aaaaagtgtc     3300

aactctttgt tatttgaaaa catgtttatt tttcttgtct ttattttaac ctttgataga     3360

accattgcaa tatgggggcc ttttgggaac ggactggtat gtaaaagaaa atccattatc     3420

gagcagcatt ttatttaccc ctcccctatc cctaggcact taaccaagac aaaaagccac     3480

aatgaacatc cctttttcaa tgaattttat aatctgcagc tctattccga gcccttagca     3540

cccattccga ccatagtata atcatatcaa agggtgagaa tcatttagca tgttgttgaa     3600

aggttttttt tcagttgttc tttttagaaa aaaagaaaaa caaaaacaaa aacaaaaaaa     3660

aaaaatcaca ccattgctca cagaattggc atctcatttt tgggacctcc catctttctg     3720

ttttgaaaag tgtacagtag tgcagtgttc ctgatgtaac tttatggctt acaatgttga     3780

catgtctcag gttcatgtgt tgcgattggt gttttccgtc tcaggtagat tgcaaagtgt     3840

aggccccaca cattggaaaa aataataata aaacaaagca aaaacaggaa attatggatt     3900

ttagttgtat attggtttat gtattttttc ttaagtatac agtgcactgt ttgaaatgta     3960

ttgttgagta ttactttgta caggttgatc acttttttta gagtgaagaa agaacaaact     4020

tgttttttgt gttttttaaa ggaatataaa ataatgaagg atgtataatt gatgccaaat     4080

aagcttgttc tttagtcaca ccgacgtctt atttttccct ttaggccagt tctgttttta     4140

aggtgtacat ggacaatgtt acagtgtaag aaactccata tccatatgtt cccattcgca     4200

ttttgtattg gttcatgtat accattttta caaaaaaaaa aagaaaaaaa agaagtacta     4260

taaaatatct gtcttcttaa taaaaaaaaa ttaatgttac aaagtgaaaa aaaaaaaaaa     4320

aaaa                                                                  4324


<210>  1807
<211>  8960
<212>  DNA
<213>  homo sapiens

<400>  1807
atgtttgttc tcttcttgtg caacctttcc ttggtaccag cggctgcttc aaagaataaa       60

gttaaaggca gccaagggca gtttccacta acacagaatg taaccgttgt tgaaggtgga      120

actgcaattt tgacctgcag ggttgatcaa aatgataaca cctccctcca gtggtcaaat      180

ccagctcaac agactctgta ctttgacgac aagaaagctt taagggacaa taggatcgag      240

ctggttcgcg cttcctggca tgaattgagt attagtgtca gtgatgtgtc tctctctgat      300

gaaggacagt acacctgttc tttatttaca atgcctgtca aaacttccaa ggcatatctc      360

accgttctgg gtgttcctga aaagcctcag attagtggat tctcatcacc agttatggag      420

ggtgacttga tgcagctgac ttgcaaaaca tctggtagta aacctgcagc tgatataaga      480

tggttcaaaa atgacaaaga gattaaagat gtaaaatatt taaaagaaga ggatgcaaat      540

cgcaagacat tcactgtcag cagcacactg gacttccgag tggaccggag tgatgatgga      600

gtggcggtca tctgcagagt agatcacgaa tccctcaatg ccacccctca ggtagccatg      660

caggtgctag aaatacacta tacaccatca gttaagatta taccatcgac tccttttcca      720

caagaaggac agcctttaat tttgacttgt gaatccaaag gaaaaccact gccagaacct      780

gttttgtgga caaaggatgg cggagaatta ccagatcctg accgaatggt tgtgagtggt      840

agggagctaa acattctttt cctgaacaaa acggataatg gtacatatcg atgtgaagcc      900

acaaacacca ttggccaaag cagtgcggaa tatgttctca ttgtgcatga tgttcccaac      960

actttgcttc ccactactat catcccctcc cttaccactg caacagtcac aaccactgta     1020

gccataacaa ccagcccaac cacatctgca acaaccagca gcatcagaga tcctaatgct     1080

ttggctggcc agaatggccc tgaccatgct ctcataggag gaatagtggc tgtagttgta     1140

tttgtcacgc tgtgttctat ctttctgctt ggtcgatatc tggcaaggca taaaggaacg     1200

tatttaacaa atgaagctaa aggagctgaa gatgcaccag atgctgatac agccattatc     1260

aatgctgaag gcagccaagt caatgctgaa gagaaaaaag agtatttcat ttaagatgca     1320

ggccaagatt ctgagtttta ctaccaggct gaatgctgga gaaaactggc tatcatcttt     1380

cagaagtcat ttctaccatc gtctgctacc cttattaact cccatactgt actgctatca     1440

gtagccagtg tataccaaca atcagctgtt gaaagcatca ttctttaatt actgtaccat     1500

ccataatgca ggacatttct tactgcctaa atttcacacc attgctcttt taacatacag     1560

tgcttgaata tacagcctta acaatgttaa tcatctcctt ggatcattat attgagtggt     1620

ttttatacat taaaaaatgt atgcagagtt tttttccccc attttttccc ctttaagtca     1680

tagaccttat cagtttgcca ttggacagct ttcacaagta acaggattag ggaaggacat     1740

aatgtattta agaataagtg aaggttagag gtttacaatt aatgttttct acatgtctgt     1800

cttcaaagac aacatgcttt ggaaacatat gtcctagaaa acataaaatt aaaaaaaaac     1860

actatagtgt agtttttgga atgttggaga ttatactggt aaagctgtat cgatttgcta     1920

ttgaaatata gtatttgata caggagccat gtgtacgaat tgcaatcatg acatggtatt     1980

ttctataatt atagagatct tactattagg atattgtagc ttcatttacc aataaattat     2040

tccaaatgat ttactgcttt tggaatcaca aatatttaat tcatttctct aatttgattc     2100

tataatttat ttgcttcata aagattcacc tgcctaaaca atattgaagt atccataggg     2160

cacaattttc agacatttta gtatctgtat atagtgcata taataaatcc aattaaacat     2220

tatttgatac atatttaact tttttggctg tatgtaattc agtcataagt aagcattttc     2280

taacgtccat tatatccctt taggtattac ttaaaccaat attataagta gataacatgt     2340

attagtattt ttgtctgtat gtcctagcac tgttcaacaa caaatttttc tagttcttgt     2400

taatttttat ttgttataca atggaagcac aatgttataa ggaaaggtaa ttttaagcta     2460

acaaccagtg cacagcctca ggttttaaat tacaaccaca gttgaataat aacctaaaaa     2520

taaattttag tttgctaaaa atttacaaat tttcattttg cagttccaga gctgcttacc     2580

tatgttggtt tgccaaaaag aagtgtttaa gatatgtttt ctgtataaat gaactaattc     2640

tttatattaa attcctgtct atgcattttg tgaggtacaa actgatgaaa cagtgagtga     2700

tagagaattt ctgccatgct tttaactcca aagtgaaagt ctctttctct ggattatttt     2760

aaaattttgg cgtgtttaac cattaagaaa tgctgtattc ttaaatatga aacagttaat     2820

ctaaagtctt attatttctt ctagtaaaat aaaatattgt tagattagtt ctcattaaat     2880

ttattatatg ctaaagaata aaactccagt tagatttaaa aaaatcccat ttacaagcat     2940

tgcaccttta agaagaaaac aaatatgaca gtatggtagc tatacttgtg atgtctgacg     3000

catgatggcc tatggtttta aaaatagtat tgtggaatat atttttgggt aataagaatg     3060

gttgagtgca acatcatgta ttaatatcaa atgaaagaca agggtgctgt atctttgatt     3120

atttatcaaa aaagtataaa tcttttaagg aaaatgttag aattttaaag tttttttttg     3180

attgttgaag catttatctt gttgatttct tacaaaagaa aaaggacgat gtcagtcaag     3240

cagcactttt tcagaatata cagaacataa ataatatgat gtggttgagt gttaacataa     3300

taaatcatat acagtatgac attttaagga aataagtctg cattgatgtg attgcatgct     3360

tgtttttaca gttcactcca taccatctgt ggaaaaatgc aataatatgt taatatagta     3420

tggtagtttg agagaatcag gtaggtgcta ctagacacat tgaaactaga ataggtttat     3480

aaactgttca tatctttcaa tgcataatct ttagaaagac tccacaaagc aaaattcatc     3540

ctgttagtac aaaatggaaa ggttcttatt acagaagtaa gttgtacaaa ctgcatcatc     3600

aattactatg taaagcctaa tttcaggatg cacttacaaa attgctactc ttcatcgatg     3660

ccgtatttac atccctcttc atttcatcta tattctactt ggctccaaca actaaattgt     3720

tgcctaaata actcaatcat tatttatagc actgtaaaat tagaaatcca aaattggttg     3780

catttcatga tttttgactc ttttaaccct tcagagtaat ataaaatctc attagaactc     3840

ttataaaacc agttagctaa aacaactaga ttattatact agttataaat gctggtatat     3900

tataatttgt gggatctaat taaatgtttg cctattaaat atagtttgat ttaaatgaga     3960

caccatgttc tgaactggag aaaacaatat caatgaagtc atattttcat acctttaaaa     4020

attatttaat tttcaaccaa acaaaaaata aattgtaaaa attatgctca tttctattcc     4080

aacaagtcag aaaataatga cataatattt ctaaatgaga atgatgtcaa tttcattgtc     4140

tggaacatgc acacttgtgt gcacatagag tcaatttctg tctcttctaa gtgagcacag     4200

taggtaggga actcaatgga agcagtgtgc acacacacac acccttagta gaatatggag     4260

cattattctt taccaaaagt agctattctc tgccagtgta ctgtttacag tgtaaattga     4320

ttgtcctccg tcaaaatcaa gtctaagcgg cattttactt ttcttttctt ttttattttc     4380

catttttggg tgttctagat aggattatta tcaaaagtag gaggaaaaag aaatgtttgt     4440

gagtgcaaga ttaaagacag agcgcatgag cagagtactg atggtgtgcg tgtttgtgtg     4500

tgtgtatatg tgtgtgtata agagagaaag agaaatcgaa aagagagaga aatttcaact     4560

tgttttcttt taccagagaa tccaagaagc agtttaagga acctgatatt ggagtttaat     4620

ctagaaactg gatgatctca tattgattca tgatgcttaa tctttcattg aaactccaca     4680

attaaaataa caaatagaga aagaaaacta actttcctaa atatggcaaa gaaactaaca     4740

cctcatttat ttttatttct ttgtaaaaat ataaatatct caatcaaaag tacaggctca     4800

tttgtaatta tgtactcatg attgtaacag cattgagatt tcatataggc acatgtatag     4860

cagctgtttg acagtgatgg ctcttccatg taacatagca gttatcgtgt aatttagtgc     4920

cacttattgc aaagtgttac caaggggaac atttcaaatg ccttttgttt ttctttggac     4980

atcaaggtaa tttagtggac aacaaatatt aaattttaca ttatgctttt taattgtgga     5040

gaaaatgcaa aacctcatgt cttaccacaa ctttcccatg gtattgctaa ttacttagag     5100

tctctaaaat tgcccaatat tatttccctt tgcaaatggt aatttctgat aaaacaatac     5160

aaaacaaaaa aaaagcagta atcacagcca aataaatgaa acacctaatg agaattactg     5220

ttgagtaatg ctttttatta agtggcacaa agtacacact aaaaactatg caaaatatag     5280

gtaactacag tgtacgtaca tgtaagtatc ttgtacttgc tgtgtatgga tgttggaaac     5340

ccatgtaatt ataatatgca ttttgaatat tgggaaagag gaaatcttag tgtagataat     5400

agaatttgtt ttgaaatata cactggcaat attgaaatat actcagtgca atatctgcag     5460

ttctattgct ggatacttaa tgcaaaggga ttttaaagaa ttcttcagca agatccaaga     5520

ggttgctaat cttcacctct cacatactaa agcattcatt aaaaatacaa ctaattcaag     5580

gacaagttaa gtttttctta ttaatgtgac acagtaacat ttttatttgg attagttttt     5640

ggtgttattg cagagaaaga aataacctga gttttaaatt tcgattcata tctcattgaa     5700

ttgggaattc ttcaattttg tttgaaatgt gtgcatgttt tcatagattg tagcaagtac     5760

aaatgtattc aatgaaagaa catagggtag ttttaatagt taaagtcact atatcttaat     5820

gggaatttta aaatatcttt tctttttcta ttcatttttt ccctttctct ctctattcta     5880

cccccaaaca agccctttgc actcataccc ttccaaaggc aatggattga aagtagcaag     5940

ataataaaga gagttaaagg ggacaacata taacaatggg ttctaaaatc atcagcattt     6000

ttatgtattg agattattaa tattgaatgc aatagttatt ggatatagct ggtaagttct     6060

ctgccatgca tacttacaat aatccttcta cctctcactt ttaacatggg ctatgatact     6120

tcaatataaa tagaggaaat aattatttac cagatatccc aggaagcatt cttatggaac     6180

tattataaca gtgcactccc caccccctgg gaaatctcaa aagccaagtt cttcagtgta     6240

ttctatggtg tatgaatctg catttgtttt tccttttcta tcattagctt ttcctaaagg     6300

caaaatatta taactttata agaatagtcc ttctcctgcc tatttaatat ttcaatgtta     6360

atataattgt attggttttt aaaaataatt aaaatggcaa cactttgcga tccaatctga     6420

tatttaattt ttaaaatgta acaatttctt ataaattcat gctgtgtttt aagtaaaaat     6480

catgtatatg aattatttta ccaagtagta ttatctgcac gagacaaatt taagtatttt     6540

aaaaatcatc cttattaata aataatcctc atataatgca cagtattgcc acaaatgccc     6600

acttcatttt gtctgcatag acatattaag aatttttcaa tgatgtaatt taattatcct     6660

aaaagaaatg acagattctt ctgtaggaaa aaataaaaac atgaatatct caaattataa     6720

tggttaatct ctaaaatatg cttaaagtaa gatgtttcta tgttatgtgg ttatgttatc     6780

aataatattt ggttgatctt cacatatttt atatgcatat atatatcaag aagttatata     6840

tatataactc aagaaactca agttatatat atatgtcaag aaatgtatga ttattttgga     6900

gagaatgggc ccaaatgtga aaaagatata aaaaaaacaa aaaaaacaaa aaaaaaacac     6960

tattttcccc tacgaaatat actgtatatt tcaaaagaag aaaagttaaa agatatttga     7020

agattgcagg ggcaaaacaa aaacctacca gggctcagca cttaagcact tttcccacat     7080

ccagggtcaa agcagcagta actacatgga cttttaagtg cggtatgaaa tgcaacatta     7140

cgcttacaaa cagtactgtc aaacctcaaa tgctttcttt cttcagatgc tttttcgtgt     7200

acatgatact agtagacact tttctcttta tatttactga tagtgaaaat catacgcaat     7260

aaaatattga tgtttgaagg cagtggtcac caattggtta aaaaactatg aaatgtaaac     7320

tgaattgtta tatctctatc ctttttgctt ttctctgtgt ttttaatgta tggaataaat     7380

ctcataaata gaaagaaaaa taatctagaa atttttcaaa gctagtactc tttctcctta     7440

taaatgtaca caattttaat ctttttacaa atttatttaa ctgtacctac tgtacttatt     7500

gtagattcaa tgacgcagtt aagtcatcac ccaaggattt atgaatttga gattactgac     7560

ctgttttctt catattgcat tcacatcaat atttgtgaat ttgttgttca gcttttcatt     7620

caaacaaaaa atattccctc aagaaagctc catttttatc ataaacattt caacataacc     7680

aacattagaa caagtctgcc atgttaaaaa taatttaaag acttatctct gaaaacggta     7740

tccagaaacg caggtgttcc cagtaatgta gcttcaaaaa taaaatgtgc tatttatatg     7800

acatgaaatt cataactttt ggaagggtat atttatgaca gcataaaaaa taaattctgt     7860

gctataaaga agatccaaca aattaaccat ataagcacag aaaatagaga aacacagtta     7920

ttgaatctac tcttgtcatt aacattttca aaaaacaaaa tgcatattgt aatatttggt     7980

acatgacact tgcatgttga tatgcctata tacttacaaa gtattcaatg tgtacttagc     8040

ggcgcttaaa atatgtcatg tacaactctt ataaacattt ttacagggtt cccatttgca     8100

cttcatcttt cagtaaagtc ttgtcagaaa aaaattgtct gataaatatg gaaaaataaa     8160

atttgaattt tagttatctg ttggacatta ctgaattgtc tattcattta gtacattttc     8220

ttaaccttga aaacagacat tgaaagatgg aactttcttt tttccagtga caggtcatta     8280

aatcgatggt acaaaacata cttctttatg ccaaacacat tattttgaat accttttttt     8340

caacttcata cattatccat ccattttagt tttcctcgat gatgcccatt ttctttgtaa     8400

atttctaagt ggaagtttta aaaattaagc atcagtaaaa taaatgttat cttatttgta     8460

caacatttaa tcgttattcc ttggaatata tgaaccttgt aaagtgatga ctaagggtca     8520

aaaaaaatgt tgctgactta gggaaatttg cttgagaatg ccaaaatttt aaaactctgt     8580

aaaggtaatt ttacattcac ttatgtgtgt ttactaatgt tgagtaggaa cagaagcaaa     8640

aatacctaaa cctatttttt ttaaccttca cactctaacc agtattatat atttcagcta     8700

cctaagataa tgcaattaat catatatcca acctaagctt ctgccaataa ggatttcaga     8760

taagctttta aatttatgga ggattttctt tgtgtctttg gaagttcact taccataaag     8820

tattttatag tctactttaa ataacagatt ttgttacaca gggtaagcca aaggctgtac     8880

aagatttagt gtcattgggt ctcatatttg tgttagacca tgaaatattc cattaaaatt     8940

tatctgtaaa tacaaggcaa                                                 8960


<210>  1808
<211>  9580
<212>  DNA
<213>  homo sapiens

<400>  1808
gtgcttcgta gagctgccgc cgtcgccgct gccgctgccg ccacagccgc cgctgcagcc       60

ggagcatccg ggagccgcca ctgccgccgc cgctgccgct gctaccgcca ctagcgctgc      120

ttccactgct tctacctccc ctcccaggac cccgagacac cccgggcgcg agcggcagtg      180

ctgcttgctt gctcctcctc tcccccagcc cttcccctcc gtgacctacc cactccttgc      240

agccctcgcc cgcaccttct ccaacacccc ggcatccctg caccacctgc tcgggcagcc      300

ccggcgggct ctgggacttg ctgtgcgcgc cgagaggaag gcaagctcca aacccctgcc      360

tggaagacgg gctgtcgcgg ctgcaccacc agcaggagga ggaggagaag aaactatttc      420

gcgatacccc attctgcggg tgctttgccg ctgccgcttc tgctgccgcc gatccgagtc      480

cgcgggttcg aacaccgcag cggtggggac ggtgggtccg gcgggcgccg ggaggaggac      540

accagcggag ccctgcactc tcgtgccccg ctcaccagca tctacttgcc ccctcgttcc      600

ttccccagcc ctttagagaa gggaccatga tttggaaacg cagcgccgtt ctccgcttct      660

acagtgtctg cgggctcctg ctacaaggca gccaagggca gtttccacta acacagaatg      720

taaccgttgt tgaaggtgga actgcaattt tgacctgcag ggttgatcaa aatgataaca      780

cctccctcca gtggtcaaat ccagctcaac agactctgta ctttgacgac aagaaagctt      840

taagggacaa taggatcgag ctggttcgcg cttcctggca tgaattgagt attagtgtca      900

gtgatgtgtc tctctctgat gaaggacagt acacctgttc tttatttaca atgcctgtca      960

aaacttccaa ggcatatctc accgttctgg gtgttcctga aaagcctcag attagtggat     1020

tctcatcacc agttatggag ggtgacttga tgcagctgac ttgcaaaaca tctggtagta     1080

aacctgcagc tgatataaga tggttcaaaa atgacaaaga gattaaagat gtaaaatatt     1140

taaaagaaga ggatgcaaat cgcaagacat tcactgtcag cagcacactg gacttccgag     1200

tggaccggag tgatgatgga gtggcggtca tctgcagagt agatcacgaa tccctcaatg     1260

ccacccctca ggtagccatg caggtgctag aaatacacta tacaccatca gttaagatta     1320

taccatcgac tccttttcca caagaaggac agcctttaat tttgacttgt gaatccaaag     1380

gaaaaccact gccagaacct gttttgtgga caaaggatgg cggagaatta ccagatcctg     1440

accgaatggt tgtgagtggt agggagctaa acattctttt cctgaacaaa acggataatg     1500

gtacatatcg atgtgaagcc acaaacacca ttggccaaag cagtgcggaa tatgttctca     1560

ttgtgcatga tgttcccaac actttgcttc ccactactat catcccctcc cttaccactg     1620

caacagtcac aaccactgta gccataacaa ccagcccaac cacatctgca acaaccagca     1680

gcatcagaga tcctaatgct ttggctggcc agaatggccc tgaccatgct ctcataggag     1740

gaatagtggc tgtagttgta tttgtcacgc tgtgttctat ctttctgctt ggtcgatatc     1800

tggcaaggca taaaggaacg tatttaacaa atgaagctaa aggagctgaa gatgcaccag     1860

atgctgatac agccattatc aatgctgaag gcagccaagt caatgctgaa gagaaaaaag     1920

agtatttcat ttaagatgca ggccaagatt ctgagtttta ctaccaggct gaatgctgga     1980

gaaaactggc tatcatcttt cagaagtcat ttctaccatc gtctgctacc cttattaact     2040

cccatactgt actgctatca gtagccagtg tataccaaca atcagctgtt gaaagcatca     2100

ttctttaatt actgtaccat ccataatgca ggacatttct tactgcctaa atttcacacc     2160

attgctcttt taacatacag tgcttgaata tacagcctta acaatgttaa tcatctcctt     2220

ggatcattat attgagtggt ttttatacat taaaaaatgt atgcagagtt tttttccccc     2280

attttttccc ctttaagtca tagaccttat cagtttgcca ttggacagct ttcacaagta     2340

acaggattag ggaaggacat aatgtattta agaataagtg aaggttagag gtttacaatt     2400

aatgttttct acatgtctgt cttcaaagac aacatgcttt ggaaacatat gtcctagaaa     2460

acataaaatt aaaaaaaaac actatagtgt agtttttgga atgttggaga ttatactggt     2520

aaagctgtat cgatttgcta ttgaaatata gtatttgata caggagccat gtgtacgaat     2580

tgcaatcatg acatggtatt ttctataatt atagagatct tactattagg atattgtagc     2640

ttcatttacc aataaattat tccaaatgat ttactgcttt tggaatcaca aatatttaat     2700

tcatttctct aatttgattc tataatttat ttgcttcata aagattcacc tgcctaaaca     2760

atattgaagt atccataggg cacaattttc agacatttta gtatctgtat atagtgcata     2820

taataaatcc aattaaacat tatttgatac atatttaact tttttggctg tatgtaattc     2880

agtcataagt aagcattttc taacgtccat tatatccctt taggtattac ttaaaccaat     2940

attataagta gataacatgt attagtattt ttgtctgtat gtcctagcac tgttcaacaa     3000

caaatttttc tagttcttgt taatttttat ttgttataca atggaagcac aatgttataa     3060

ggaaaggtaa ttttaagcta acaaccagtg cacagcctca ggttttaaat tacaaccaca     3120

gttgaataat aacctaaaaa taaattttag tttgctaaaa atttacaaat tttcattttg     3180

cagttccaga gctgcttacc tatgttggtt tgccaaaaag aagtgtttaa gatatgtttt     3240

ctgtataaat gaactaattc tttatattaa attcctgtct atgcattttg tgaggtacaa     3300

actgatgaaa cagtgagtga tagagaattt ctgccatgct tttaactcca aagtgaaagt     3360

ctctttctct ggattatttt aaaattttgg cgtgtttaac cattaagaaa tgctgtattc     3420

ttaaatatga aacagttaat ctaaagtctt attatttctt ctagtaaaat aaaatattgt     3480

tagattagtt ctcattaaat ttattatatg ctaaagaata aaactccagt tagatttaaa     3540

aaaatcccat ttacaagcat tgcaccttta agaagaaaac aaatatgaca gtatggtagc     3600

tatacttgtg atgtctgacg catgatggcc tatggtttta aaaatagtat tgtggaatat     3660

atttttgggt aataagaatg gttgagtgca acatcatgta ttaatatcaa atgaaagaca     3720

agggtgctgt atctttgatt atttatcaaa aaagtataaa tcttttaagg aaaatgttag     3780

aattttaaag tttttttttg attgttgaag catttatctt gttgatttct tacaaaagaa     3840

aaaggacgat gtcagtcaag cagcactttt tcagaatata cagaacataa ataatatgat     3900

gtggttgagt gttaacataa taaatcatat acagtatgac attttaagga aataagtctg     3960

cattgatgtg attgcatgct tgtttttaca gttcactcca taccatctgt ggaaaaatgc     4020

aataatatgt taatatagta tggtagtttg agagaatcag gtaggtgcta ctagacacat     4080

tgaaactaga ataggtttat aaactgttca tatctttcaa tgcataatct ttagaaagac     4140

tccacaaagc aaaattcatc ctgttagtac aaaatggaaa ggttcttatt acagaagtaa     4200

gttgtacaaa ctgcatcatc aattactatg taaagcctaa tttcaggatg cacttacaaa     4260

attgctactc ttcatcgatg ccgtatttac atccctcttc atttcatcta tattctactt     4320

ggctccaaca actaaattgt tgcctaaata actcaatcat tatttatagc actgtaaaat     4380

tagaaatcca aaattggttg catttcatga tttttgactc ttttaaccct tcagagtaat     4440

ataaaatctc attagaactc ttataaaacc agttagctaa aacaactaga ttattatact     4500

agttataaat gctggtatat tataatttgt gggatctaat taaatgtttg cctattaaat     4560

atagtttgat ttaaatgaga caccatgttc tgaactggag aaaacaatat caatgaagtc     4620

atattttcat acctttaaaa attatttaat tttcaaccaa acaaaaaata aattgtaaaa     4680

attatgctca tttctattcc aacaagtcag aaaataatga cataatattt ctaaatgaga     4740

atgatgtcaa tttcattgtc tggaacatgc acacttgtgt gcacatagag tcaatttctg     4800

tctcttctaa gtgagcacag taggtaggga actcaatgga agcagtgtgc acacacacac     4860

acccttagta gaatatggag cattattctt taccaaaagt agctattctc tgccagtgta     4920

ctgtttacag tgtaaattga ttgtcctccg tcaaaatcaa gtctaagcgg cattttactt     4980

ttcttttctt ttttattttc catttttggg tgttctagat aggattatta tcaaaagtag     5040

gaggaaaaag aaatgtttgt gagtgcaaga ttaaagacag agcgcatgag cagagtactg     5100

atggtgtgcg tgtttgtgtg tgtgtatatg tgtgtgtata agagagaaag agaaatcgaa     5160

aagagagaga aatttcaact tgttttcttt taccagagaa tccaagaagc agtttaagga     5220

acctgatatt ggagtttaat ctagaaactg gatgatctca tattgattca tgatgcttaa     5280

tctttcattg aaactccaca attaaaataa caaatagaga aagaaaacta actttcctaa     5340

atatggcaaa gaaactaaca cctcatttat ttttatttct ttgtaaaaat ataaatatct     5400

caatcaaaag tacaggctca tttgtaatta tgtactcatg attgtaacag cattgagatt     5460

tcatataggc acatgtatag cagctgtttg acagtgatgg ctcttccatg taacatagca     5520

gttatcgtgt aatttagtgc cacttattgc aaagtgttac caaggggaac atttcaaatg     5580

ccttttgttt ttctttggac atcaaggtaa tttagtggac aacaaatatt aaattttaca     5640

ttatgctttt taattgtgga gaaaatgcaa aacctcatgt cttaccacaa ctttcccatg     5700

gtattgctaa ttacttagag tctctaaaat tgcccaatat tatttccctt tgcaaatggt     5760

aatttctgat aaaacaatac aaaacaaaaa aaaagcagta atcacagcca aataaatgaa     5820

acacctaatg agaattactg ttgagtaatg ctttttatta agtggcacaa agtacacact     5880

aaaaactatg caaaatatag gtaactacag tgtacgtaca tgtaagtatc ttgtacttgc     5940

tgtgtatgga tgttggaaac ccatgtaatt ataatatgca ttttgaatat tgggaaagag     6000

gaaatcttag tgtagataat agaatttgtt ttgaaatata cactggcaat attgaaatat     6060

actcagtgca atatctgcag ttctattgct ggatacttaa tgcaaaggga ttttaaagaa     6120

ttcttcagca agatccaaga ggttgctaat cttcacctct cacatactaa agcattcatt     6180

aaaaatacaa ctaattcaag gacaagttaa gtttttctta ttaatgtgac acagtaacat     6240

ttttatttgg attagttttt ggtgttattg cagagaaaga aataacctga gttttaaatt     6300

tcgattcata tctcattgaa ttgggaattc ttcaattttg tttgaaatgt gtgcatgttt     6360

tcatagattg tagcaagtac aaatgtattc aatgaaagaa catagggtag ttttaatagt     6420

taaagtcact atatcttaat gggaatttta aaatatcttt tctttttcta ttcatttttt     6480

ccctttctct ctctattcta cccccaaaca agccctttgc actcataccc ttccaaaggc     6540

aatggattga aagtagcaag ataataaaga gagttaaagg ggacaacata taacaatggg     6600

ttctaaaatc atcagcattt ttatgtattg agattattaa tattgaatgc aatagttatt     6660

ggatatagct ggtaagttct ctgccatgca tacttacaat aatccttcta cctctcactt     6720

ttaacatggg ctatgatact tcaatataaa tagaggaaat aattatttac cagatatccc     6780

aggaagcatt cttatggaac tattataaca gtgcactccc caccccctgg gaaatctcaa     6840

aagccaagtt cttcagtgta ttctatggtg tatgaatctg catttgtttt tccttttcta     6900

tcattagctt ttcctaaagg caaaatatta taactttata agaatagtcc ttctcctgcc     6960

tatttaatat ttcaatgtta atataattgt attggttttt aaaaataatt aaaatggcaa     7020

cactttgcga tccaatctga tatttaattt ttaaaatgta acaatttctt ataaattcat     7080

gctgtgtttt aagtaaaaat catgtatatg aattatttta ccaagtagta ttatctgcac     7140

gagacaaatt taagtatttt aaaaatcatc cttattaata aataatcctc atataatgca     7200

cagtattgcc acaaatgccc acttcatttt gtctgcatag acatattaag aatttttcaa     7260

tgatgtaatt taattatcct aaaagaaatg acagattctt ctgtaggaaa aaataaaaac     7320

atgaatatct caaattataa tggttaatct ctaaaatatg cttaaagtaa gatgtttcta     7380

tgttatgtgg ttatgttatc aataatattt ggttgatctt cacatatttt atatgcatat     7440

atatatcaag aagttatata tatataactc aagaaactca agttatatat atatgtcaag     7500

aaatgtatga ttattttgga gagaatgggc ccaaatgtga aaaagatata aaaaaaacaa     7560

aaaaaacaaa aaaaaaacac tattttcccc tacgaaatat actgtatatt tcaaaagaag     7620

aaaagttaaa agatatttga agattgcagg ggcaaaacaa aaacctacca gggctcagca     7680

cttaagcact tttcccacat ccagggtcaa agcagcagta actacatgga cttttaagtg     7740

cggtatgaaa tgcaacatta cgcttacaaa cagtactgtc aaacctcaaa tgctttcttt     7800

cttcagatgc tttttcgtgt acatgatact agtagacact tttctcttta tatttactga     7860

tagtgaaaat catacgcaat aaaatattga tgtttgaagg cagtggtcac caattggtta     7920

aaaaactatg aaatgtaaac tgaattgtta tatctctatc ctttttgctt ttctctgtgt     7980

ttttaatgta tggaataaat ctcataaata gaaagaaaaa taatctagaa atttttcaaa     8040

gctagtactc tttctcctta taaatgtaca caattttaat ctttttacaa atttatttaa     8100

ctgtacctac tgtacttatt gtagattcaa tgacgcagtt aagtcatcac ccaaggattt     8160

atgaatttga gattactgac ctgttttctt catattgcat tcacatcaat atttgtgaat     8220

ttgttgttca gcttttcatt caaacaaaaa atattccctc aagaaagctc catttttatc     8280

ataaacattt caacataacc aacattagaa caagtctgcc atgttaaaaa taatttaaag     8340

acttatctct gaaaacggta tccagaaacg caggtgttcc cagtaatgta gcttcaaaaa     8400

taaaatgtgc tatttatatg acatgaaatt cataactttt ggaagggtat atttatgaca     8460

gcataaaaaa taaattctgt gctataaaga agatccaaca aattaaccat ataagcacag     8520

aaaatagaga aacacagtta ttgaatctac tcttgtcatt aacattttca aaaaacaaaa     8580

tgcatattgt aatatttggt acatgacact tgcatgttga tatgcctata tacttacaaa     8640

gtattcaatg tgtacttagc ggcgcttaaa atatgtcatg tacaactctt ataaacattt     8700

ttacagggtt cccatttgca cttcatcttt cagtaaagtc ttgtcagaaa aaaattgtct     8760

gataaatatg gaaaaataaa atttgaattt tagttatctg ttggacatta ctgaattgtc     8820

tattcattta gtacattttc ttaaccttga aaacagacat tgaaagatgg aactttcttt     8880

tttccagtga caggtcatta aatcgatggt acaaaacata cttctttatg ccaaacacat     8940

tattttgaat accttttttt caacttcata cattatccat ccattttagt tttcctcgat     9000

gatgcccatt ttctttgtaa atttctaagt ggaagtttta aaaattaagc atcagtaaaa     9060

taaatgttat cttatttgta caacatttaa tcgttattcc ttggaatata tgaaccttgt     9120

aaagtgatga ctaagggtca aaaaaaatgt tgctgactta gggaaatttg cttgagaatg     9180

ccaaaatttt aaaactctgt aaaggtaatt ttacattcac ttatgtgtgt ttactaatgt     9240

tgagtaggaa cagaagcaaa aatacctaaa cctatttttt ttaaccttca cactctaacc     9300

agtattatat atttcagcta cctaagataa tgcaattaat catatatcca acctaagctt     9360

ctgccaataa ggatttcaga taagctttta aatttatgga ggattttctt tgtgtctttg     9420

gaagttcact taccataaag tattttatag tctactttaa ataacagatt ttgttacaca     9480

gggtaagcca aaggctgtac aagatttagt gtcattgggt ctcatatttg tgttagacca     9540

tgaaatattc cattaaaatt tatctgtaaa tacaaggcaa                           9580


<210>  1809
<211>  3413
<212>  DNA
<213>  homo sapiens

<400>  1809
ctgctccgta ccctccgccc cttcagtctg gggctccggg taaagtttca gcctccgcac       60

gtgactcgct atggccgctg ccatcgcccc gcgcccctga gccgcggccc cctggacggc      120

tcctctcccg ggaccccgca ccctgatgcc gagcagcacc agggcgccgg gttagggcag      180

acgctgtgct cgctggcacc ccgaacgggt tgcttccccc gctgcgagca tcacaggaca      240

tggccccctc agccacctag ctggggccca tctaggagtg gcatcttttt tggtgccctg      300

aaggccagct ctggaccttc ccaggaaaag tgccagctca cagaactgct tgaccaaagg      360

accggctctt gagacatccc ccaacccacc tggcccccag ctagggtggg ggctccagga      420

gactgagatt agcctgccct ctttggacag cagctccagg acagggcggg tgggctgacc      480

acccaaaccc catctgggcc caggccccat gccccgagga ggggtggtct gaagcccacc      540

agagccccct gccagactgt ctgcctccct tctgactgtg gccgcttggc atggccagca      600

acagcagctc ctgcccgaca cctgggggcg ggcacctcaa tgggtacccg gtgcctccct      660

acgccttctt cttcccccct atgctgggtg gactctcccc gccaggcgct ctgaccactc      720

tccagcacca gcttccagtt agtggatata gcacaccatc cccagccacc attgagaccc      780

agagcagcag ttctgaagag atagtgccca gccctccctc gccaccccct ctaccccgca      840

tctacaagcc ttgctttgtc tgtcaggaca agtcctcagg ctaccactat ggggtcagcg      900

cctgtgaggg ctgcaagggc ttcttccgcc gcagcatcca gaagaacatg gtgtacacgt      960

gtcaccggga caagaactgc atcatcaaca aggtgacccg gaaccgctgc cagtactgcc     1020

gactgcagaa gtgctttgaa gtgggcatgt ccaaggagtc tgtgagaaac gaccgaaaca     1080

agaagaagaa ggaggtgccc aagcccgagt gctctgagag ctacacgctg acgccggagg     1140

tgggggagct cattgagaag gtgcgcaaag cgcaccagga aaccttccct gccctctgcc     1200

agctgggcaa atacactacg aacaacagct cagaacaacg tgtctctctg gacattgacc     1260

tctgggacaa gttcagtgaa ctctccacca agtgcatcat taagactgtg gagttcgcca     1320

agcagctgcc cggcttcacc accctcacca tcgccgacca gatcaccctc ctcaaggctg     1380

cctgcctgga catcctgatc ctgcggatct gcacgcggta cacgcccgag caggacacca     1440

tgaccttctc ggacgggctg accctgaacc ggacccagat gcacaacgct ggcttcggcc     1500

ccctcaccga cctggtcttt gccttcgcca accagctgct gcccctggag atggatgatg     1560

cggagacggg gctgctcagc gccatctgcc tcatctgcgg agaccgccag gacctggagc     1620

agccggaccg ggtggacatg ctgcaggagc cgctgctgga ggcgctaaag gtctacgtgc     1680

ggaagcggag gcccagccgc ccccacatgt tccccaagat gctaatgaag attactgacc     1740

tgcgaagcat cagcgccaag ggggctgagc gggtgatcac gctgaagatg gagatcccgg     1800

gctccatgcc gcctctcatc caggaaatgt tggagaactc agagggcctg gacactctga     1860

gcggacagcc ggggggtggg gggcgggacg ggggtggcct ggcccccccg ccaggcagct     1920

gtagccccag cctcagcccc agctccaaca gaagcagccc ggccacccac tccccgtgac     1980

cgcccacgcc acatggacac agccctcgcc ctccgccccg gcttttctct gcctttctac     2040

cgaccatgtg accccgcacc agccctgccc ccacctgccc tcccgggcag tactggggac     2100

cttccctggg ggacggggag ggaggaggca gcgactcctt ggacagaggc ctgggccctc     2160

agtggactgc ctgctcccac agcctgggct gacgtcagag gccgaggcca ggaactgagt     2220

gaggcccctg gtcctgggtc tcaggatggg tcctgggggc ctcgtgttca tcaagacacc     2280

cctctgccca gctcaccaca tcttcatcac cagcaaacgc caggacttgg ctcccccatc     2340

ctcagaactc acaagccatt gctccccagc tggggaacct caacctcccc cctgcctcgg     2400

ttggtgacag agggggtggg acaggggcgg ggggttcccc ctgtacatac cctgccatac     2460

caaccccagg tattaattct cgctggtttt gtttttattt taattttttt gttttgattt     2520

ttttaataag aattttcatt ttaagcacat ttatactgaa ggaatttgtg ctgtgtattg     2580

gggggagctg gatccagagc tggagggggt gggtccgggg gagggagtgg ctcggaaggg     2640

gcccccactc tcctttcatg tccctgtgcc ccccagttct cctcctcagc cttttcctcc     2700

tcagttttct ctttaaaact gtgaagtact aactttccaa ggcctgcctt cccctccctc     2760

ccactggaga agccgccagc ccctttctcc ctctgcctga ccactgggtg tggacggtgt     2820

ggggcagccc tgaaaggaca ggctcctggc cttggcactt gcctgcaccc accatgaggc     2880

atggagcagg gcagagcaag ggccccggga cagagttttc ccagacctgg ctcctcggca     2940

gagctgcctc ccgtcagggc ccacatcatc taggctcccc agcccccact gtgaaggggc     3000

tggccagggg cccgagctgc ccccaccccc ggcctcagcc accagcaccc ccatagggcc     3060

cccagacacc acacacatgc gcgtgcgcac acacacaaac acacacacac tggacagtag     3120

atgggccgac acacacttgg cccgagttcc tccatttccc tggcctgccc cccaccccca     3180

acctgtccca cccccgtgcc ccctccttac cccgcaggac gggcctacag gggggtctcc     3240

cctcacccct gcacccccag ctgggggagc tggctctgcc ccgacctcct tcaccagggg     3300

ttggggcccc ttcccctgga gcccgtgggt gcacctgtta ctgttgggct ttccactgag     3360

atctactgga taaagaataa agttctattt attctaaaaa aaaaaaaaaa aaa            3413


<210>  1810
<211>  3494
<212>  DNA
<213>  homo sapiens

<400>  1810
ctcggttccc tgcgtttctc ccgctgcagc cggacgcgcc gggaatgggt taagccaggg       60

gcggtgcctg gacggggcgg ggcggtggaa agggggtggt gcccggaggg gagggggcgc      120

gcagagctgg ggtggggggg ccgtggcgcg taccaccaga gaccgagcga gtcgccagct      180

gcccctggcc tggcgggggc ggaaccgcgc gggatcccca cccccacccg gaatcctcgc      240

cacggagaat ccctggagaa gccccggatc cccggctggg aggaggaagt gctcgttgac      300

ccccagcccc gcgctgatcc cgcccccggc ctgcggactt ggggagccgc tgtactctgc      360

ctcggacgcc acgagactct agacgggagt cccctcgagg tgaagccgct gagttcccgg      420

gccccgccag gcttccctgg gagagccgac ggaccccccc tcccagcaca cacaacttcc      480

ctgcttttca ccgggactgg cggagcggcc ggcggactta gacgcgggga cttcagggca      540

gggggcgccc cctgcccggg tcaccagtcg gggcgagggg acgtctcctc tcccccagct      600

gctctgctcg gatggcgccg ccggctgagt gacgggggcg gcgcgcagga cttcccagct      660

cggacctctt gccttcgagg ggaaagatgt acgagagtgt agaagtgggg ggtcccaccc      720

ctaatccctt cctagtggtg gatttttata accagaaccg ggcctgtttg ctcccagaga      780

aggggctccc cgccccgggt ccgtactcca ccccgctccg gactccgctt tggaatggct      840

caaaccactc cattgagacc cagagcagca gttctgaaga gatagtgccc agccctccct      900

cgccaccccc tctaccccgc atctacaagc cttgctttgt ctgtcaggac aagtcctcag      960

gctaccacta tggggtcagc gcctgtgagg gctgcaaggg cttcttccgc cgcagcatcc     1020

agaagaacat ggtgtacacg tgtcaccggg acaagaactg catcatcaac aaggtgaccc     1080

ggaaccgctg ccagtactgc cgactgcaga agtgctttga agtgggcatg tccaaggagt     1140

ctgtgagaaa cgaccgaaac aagaagaaga aggaggtgcc caagcccgag tgctctgaga     1200

gctacacgct gacgccggag gtgggggagc tcattgagaa ggtgcgcaaa gcgcaccagg     1260

aaaccttccc tgccctctgc cagctgggca aatacactac gaacaacagc tcagaacaac     1320

gtgtctctct ggacattgac ctctgggaca agttcagtga actctccacc aagtgcatca     1380

ttaagactgt ggagttcgcc aagcagctgc ccggcttcac caccctcacc atcgccgacc     1440

agatcaccct cctcaaggct gcctgcctgg acatcctgat cctgcggatc tgcacgcggt     1500

acacgcccga gcaggacacc atgaccttct cggacgggct gaccctgaac cggacccaga     1560

tgcacaacgc tggcttcggc cccctcaccg acctggtctt tgccttcgcc aaccagctgc     1620

tgcccctgga gatggatgat gcggagacgg ggctgctcag cgccatctgc ctcatctgcg     1680

gagaccgcca ggacctggag cagccggacc gggtggacat gctgcaggag ccgctgctgg     1740

aggcgctaaa ggtctacgtg cggaagcgga ggcccagccg cccccacatg ttccccaaga     1800

tgctaatgaa gattactgac ctgcgaagca tcagcgccaa gggggctgag cgggtgatca     1860

cgctgaagat ggagatcccg ggctccatgc cgcctctcat ccaggaaatg ttggagaact     1920

cagagggcct ggacactctg agcggacagc cggggggtgg ggggcgggac gggggtggcc     1980

tggccccccc gccaggcagc tgtagcccca gcctcagccc cagctccaac agaagcagcc     2040

cggccaccca ctccccgtga ccgcccacgc cacatggaca cagccctcgc cctccgcccc     2100

ggcttttctc tgcctttcta ccgaccatgt gaccccgcac cagccctgcc cccacctgcc     2160

ctcccgggca gtactgggga ccttccctgg gggacgggga gggaggaggc agcgactcct     2220

tggacagagg cctgggccct cagtggactg cctgctccca cagcctgggc tgacgtcaga     2280

ggccgaggcc aggaactgag tgaggcccct ggtcctgggt ctcaggatgg gtcctggggg     2340

cctcgtgttc atcaagacac ccctctgccc agctcaccac atcttcatca ccagcaaacg     2400

ccaggacttg gctcccccat cctcagaact cacaagccat tgctccccag ctggggaacc     2460

tcaacctccc ccctgcctcg gttggtgaca gagggggtgg gacaggggcg gggggttccc     2520

cctgtacata ccctgccata ccaaccccag gtattaattc tcgctggttt tgtttttatt     2580

ttaatttttt tgttttgatt tttttaataa gaattttcat tttaagcaca tttatactga     2640

aggaatttgt gctgtgtatt ggggggagct ggatccagag ctggaggggg tgggtccggg     2700

ggagggagtg gctcggaagg ggcccccact ctcctttcat gtccctgtgc cccccagttc     2760

tcctcctcag ccttttcctc ctcagttttc tctttaaaac tgtgaagtac taactttcca     2820

aggcctgcct tcccctccct cccactggag aagccgccag cccctttctc cctctgcctg     2880

accactgggt gtggacggtg tggggcagcc ctgaaaggac aggctcctgg ccttggcact     2940

tgcctgcacc caccatgagg catggagcag ggcagagcaa gggccccggg acagagtttt     3000

cccagacctg gctcctcggc agagctgcct cccgtcaggg cccacatcat ctaggctccc     3060

cagcccccac tgtgaagggg ctggccaggg gcccgagctg cccccacccc cggcctcagc     3120

caccagcacc cccatagggc ccccagacac cacacacatg cgcgtgcgca cacacacaaa     3180

cacacacaca ctggacagta gatgggccga cacacacttg gcccgagttc ctccatttcc     3240

ctggcctgcc ccccaccccc aacctgtccc acccccgtgc cccctcctta ccccgcagga     3300

cgggcctaca ggggggtctc ccctcacccc tgcaccccca gctgggggag ctggctctgc     3360

cccgacctcc ttcaccaggg gttggggccc cttcccctgg agcccgtggg tgcacctgtt     3420

actgttgggc tttccactga gatctactgg ataaagaata aagttctatt tattctaaaa     3480

aaaaaaaaaa aaaa                                                       3494


<210>  1811
<211>  3122
<212>  DNA
<213>  homo sapiens

<400>  1811
ctgctccgta ccctccgccc cttcagtctg gggctccggg taaagtttca gcctccgcac       60

gtgactcgct atggccgctg ccatcgcccc gcgcccctga gccgcggccc cctggacggc      120

tcctctcccg ggaccccgca ccctgatgcc gagcagcacc agggcgccgg gttagggcag      180

acgctgtgct cgctggcacc ccgaacgggt tgcttccccc gctgcgagca tcacaggaca      240

tggccccctc agccacctag ctggggccca tctaggagtg gcatcttttt tggtgccctg      300

aaggccagct ctggaccttc ccaggaaaag tgccagctca cagaactgct tgaccaaagg      360

accggctctt gagacatccc ccaacccacc tggcccccag ctagggtggg ggctccagga      420

gactgagatt agcctgccct ctttggacag cagctccagg acagggcggg tgggctgacc      480

acccaaaccc catctgggcc caggccccat gccccgagga ggggtggtct gaagcccacc      540

agagccccct gccagactgt ctgcctccct tctgactgtg gccgcttggc atggccagca      600

acagcagctc ctgcccgaca cctgggggcg ggcacctcaa tgggtacccg gtgcctccct      660

acgccttctt cttcccccct atgctgggtg gactctcccc gccaggcgct ctgaccactc      720

tccagcacca gcttccagtt agtggatata gcacaccatc cccagccact gtgagaaacg      780

accgaaacaa gaagaagaag gaggtgccca agcccgagtg ctctgagagc tacacgctga      840

cgccggaggt gggggagctc attgagaagg tgcgcaaagc gcaccaggaa accttccctg      900

ccctctgcca gctgggcaaa tacactacga acaacagctc agaacaacgt gtctctctgg      960

acattgacct ctgggacaag ttcagtgaac tctccaccaa gtgcatcatt aagactgtgg     1020

agttcgccaa gcagctgccc ggcttcacca ccctcaccat cgccgaccag atcaccctcc     1080

tcaaggctgc ctgcctggac atcctgatcc tgcggatctg cacgcggtac acgcccgagc     1140

aggacaccat gaccttctcg gacgggctga ccctgaaccg gacccagatg cacaacgctg     1200

gcttcggccc cctcaccgac ctggtctttg ccttcgccaa ccagctgctg cccctggaga     1260

tggatgatgc ggagacgggg ctgctcagcg ccatctgcct catctgcgga gaccgccagg     1320

acctggagca gccggaccgg gtggacatgc tgcaggagcc gctgctggag gcgctaaagg     1380

tctacgtgcg gaagcggagg cccagccgcc cccacatgtt ccccaagatg ctaatgaaga     1440

ttactgacct gcgaagcatc agcgccaagg gggctgagcg ggtgatcacg ctgaagatgg     1500

agatcccggg ctccatgccg cctctcatcc aggaaatgtt ggagaactca gagggcctgg     1560

acactctgag cggacagccg gggggtgggg ggcgggacgg gggtggcctg gcccccccgc     1620

caggcagctg tagccccagc ctcagcccca gctccaacag aagcagcccg gccacccact     1680

ccccgtgacc gcccacgcca catggacaca gccctcgccc tccgccccgg cttttctctg     1740

cctttctacc gaccatgtga ccccgcacca gccctgcccc cacctgccct cccgggcagt     1800

actggggacc ttccctgggg gacggggagg gaggaggcag cgactccttg gacagaggcc     1860

tgggccctca gtggactgcc tgctcccaca gcctgggctg acgtcagagg ccgaggccag     1920

gaactgagtg aggcccctgg tcctgggtct caggatgggt cctgggggcc tcgtgttcat     1980

caagacaccc ctctgcccag ctcaccacat cttcatcacc agcaaacgcc aggacttggc     2040

tcccccatcc tcagaactca caagccattg ctccccagct ggggaacctc aacctccccc     2100

ctgcctcggt tggtgacaga gggggtggga caggggcggg gggttccccc tgtacatacc     2160

ctgccatacc aaccccaggt attaattctc gctggttttg tttttatttt aatttttttg     2220

ttttgatttt tttaataaga attttcattt taagcacatt tatactgaag gaatttgtgc     2280

tgtgtattgg ggggagctgg atccagagct ggagggggtg ggtccggggg agggagtggc     2340

tcggaagggg cccccactct cctttcatgt ccctgtgccc cccagttctc ctcctcagcc     2400

ttttcctcct cagttttctc tttaaaactg tgaagtacta actttccaag gcctgccttc     2460

ccctccctcc cactggagaa gccgccagcc cctttctccc tctgcctgac cactgggtgt     2520

ggacggtgtg gggcagccct gaaaggacag gctcctggcc ttggcacttg cctgcaccca     2580

ccatgaggca tggagcaggg cagagcaagg gccccgggac agagttttcc cagacctggc     2640

tcctcggcag agctgcctcc cgtcagggcc cacatcatct aggctcccca gcccccactg     2700

tgaaggggct ggccaggggc ccgagctgcc cccacccccg gcctcagcca ccagcacccc     2760

catagggccc ccagacacca cacacatgcg cgtgcgcaca cacacaaaca cacacacact     2820

ggacagtaga tgggccgaca cacacttggc ccgagttcct ccatttccct ggcctgcccc     2880

ccacccccaa cctgtcccac ccccgtgccc cctccttacc ccgcaggacg ggcctacagg     2940

ggggtctccc ctcacccctg cacccccagc tgggggagct ggctctgccc cgacctcctt     3000

caccaggggt tggggcccct tcccctggag cccgtgggtg cacctgttac tgttgggctt     3060

tccactgaga tctactggat aaagaataaa gttctattta ttctaaaaaa aaaaaaaaaa     3120

aa                                                                    3122


<210>  1812
<211>  3301
<212>  DNA
<213>  homo sapiens

<400>  1812
gtgcctcttg cagcagccta acccagaagc aggggggaat cctgaatcga gctgagaggg       60

cttccccggt tctcctggga accccatcgg ccccctgcca gcacacacct gagcagcatc      120

acaggacatg gccccctcag ccacctagct ggggcccatc taggagtggc atcttttttg      180

gtgccctgaa ggccagctct ggaccttccc aggaaaagtg ccagctcaca gaactgcttg      240

accaaaggac cggctcttga gacatccccc aacccacctg gcccccagct agggtggggg      300

ctccaggaga ctgagattag cctgccctct ttggacagca gctccaggac agggcgggtg      360

ggctgaccac ccaaacccca tctgggccca ggccccatgc cccgaggagg ggtggtctga      420

agcccaccag agccccctgc cagactgtct gcctcccttc tgactgtggc cgcttggcat      480

ggccagcaac agcagctcct gcccgacacc tgggggcggg cacctcaatg ggtacccggt      540

gcctccctac gccttcttct tcccccctat gctgggtgga ctctccccgc caggcgctct      600

gaccactctc cagcaccagc ttccagttag tggatatagc acaccatccc cagccaccat      660

tgagacccag agcagcagtt ctgaagagat agtgcccagc cctccctcgc caccccctct      720

accccgcatc tacaagcctt gctttgtctg tcaggacaag tcctcaggct accactatgg      780

ggtcagcgcc tgtgagggct gcaagggctt cttccgccgc agcatccaga agaacatggt      840

gtacacgtgt caccgggaca agaactgcat catcaacaag gtgacccgga accgctgcca      900

gtactgccga ctgcagaagt gctttgaagt gggcatgtcc aaggagtctg tgagaaacga      960

ccgaaacaag aagaagaagg aggtgcccaa gcccgagtgc tctgagagct acacgctgac     1020

gccggaggtg ggggagctca ttgagaaggt gcgcaaagcg caccaggaaa ccttccctgc     1080

cctctgccag ctgggcaaat acactacgaa caacagctca gaacaacgtg tctctctgga     1140

cattgacctc tgggacaagt tcagtgaact ctccaccaag tgcatcatta agactgtgga     1200

gttcgccaag cagctgcccg gcttcaccac cctcaccatc gccgaccaga tcaccctcct     1260

caaggctgcc tgcctggaca tcctgatcct gcggatctgc acgcggtaca cgcccgagca     1320

ggacaccatg accttctcgg acgggctgac cctgaaccgg acccagatgc acaacgctgg     1380

cttcggcccc ctcaccgacc tggtctttgc cttcgccaac cagctgctgc ccctggagat     1440

ggatgatgcg gagacggggc tgctcagcgc catctgcctc atctgcggag accgccagga     1500

cctggagcag ccggaccggg tggacatgct gcaggagccg ctgctggagg cgctaaaggt     1560

ctacgtgcgg aagcggaggc ccagccgccc ccacatgttc cccaagatgc taatgaagat     1620

tactgacctg cgaagcatca gcgccaaggg ggctgagcgg gtgatcacgc tgaagatgga     1680

gatcccgggc tccatgccgc ctctcatcca ggaaatgttg gagaactcag agggcctgga     1740

cactctgagc ggacagccgg ggggtggggg gcgggacggg ggtggcctgg cccccccgcc     1800

aggcagctgt agccccagcc tcagccccag ctccaacaga agcagcccgg ccacccactc     1860

cccgtgaccg cccacgccac atggacacag ccctcgccct ccgccccggc ttttctctgc     1920

ctttctaccg accatgtgac cccgcaccag ccctgccccc acctgccctc ccgggcagta     1980

ctggggacct tccctggggg acggggaggg aggaggcagc gactccttgg acagaggcct     2040

gggccctcag tggactgcct gctcccacag cctgggctga cgtcagaggc cgaggccagg     2100

aactgagtga ggcccctggt cctgggtctc aggatgggtc ctgggggcct cgtgttcatc     2160

aagacacccc tctgcccagc tcaccacatc ttcatcacca gcaaacgcca ggacttggct     2220

cccccatcct cagaactcac aagccattgc tccccagctg gggaacctca acctcccccc     2280

tgcctcggtt ggtgacagag ggggtgggac aggggcgggg ggttccccct gtacataccc     2340

tgccatacca accccaggta ttaattctcg ctggttttgt ttttatttta atttttttgt     2400

tttgattttt ttaataagaa ttttcatttt aagcacattt atactgaagg aatttgtgct     2460

gtgtattggg gggagctgga tccagagctg gagggggtgg gtccggggga gggagtggct     2520

cggaaggggc ccccactctc ctttcatgtc cctgtgcccc ccagttctcc tcctcagcct     2580

tttcctcctc agttttctct ttaaaactgt gaagtactaa ctttccaagg cctgccttcc     2640

cctccctccc actggagaag ccgccagccc ctttctccct ctgcctgacc actgggtgtg     2700

gacggtgtgg ggcagccctg aaaggacagg ctcctggcct tggcacttgc ctgcacccac     2760

catgaggcat ggagcagggc agagcaaggg ccccgggaca gagttttccc agacctggct     2820

cctcggcaga gctgcctccc gtcagggccc acatcatcta ggctccccag cccccactgt     2880

gaaggggctg gccaggggcc cgagctgccc ccacccccgg cctcagccac cagcaccccc     2940

atagggcccc cagacaccac acacatgcgc gtgcgcacac acacaaacac acacacactg     3000

gacagtagat gggccgacac acacttggcc cgagttcctc catttccctg gcctgccccc     3060

cacccccaac ctgtcccacc cccgtgcccc ctccttaccc cgcaggacgg gcctacaggg     3120

gggtctcccc tcacccctgc acccccagct gggggagctg gctctgcccc gacctccttc     3180

accaggggtt ggggcccctt cccctggagc ccgtgggtgc acctgttact gttgggcttt     3240

ccactgagat ctactggata aagaataaag ttctatttat tctaaaaaaa aaaaaaaaaa     3300

a                                                                     3301


<210>  1813
<211>  3979
<212>  DNA
<213>  homo sapiens

<400>  1813
gaacccgcct gtcagccagc ctttcgagct aattagctca gcatacaaca aagataagtg       60

agcctgggaa gagggccccc tgaggggtct ttagattctg ggaaatgtct gattggcaga      120

tgttaaaagg gattccttgg taatccagtg catcaatgag ctgcagaaat tcagcccagg      180

actgcaagaa ttcaggcatg aggacactct gtacaggagg ctcacacagg cagacccaag      240

atggacagaa ccttggaatc tctgagacac atcattgccc aagtcttgcc tcacagagat      300

ccggctctag tcttcaaaga cttgaacgtt gtgtcaatgt tacaggaatt ttgggaaagc      360

aagcagcagc agaaggctgc attcccaagt gaaggtgtgg tggtctatga gtcactgcca      420

gctcctgggc ctccctttgt gagttacgtg accctcccag ggggaagctg ttttggcaac      480

tttcagtgct gcttaagtag agccgaggcc aggcgggatg cagctaaagt ggccctgatc      540

aactccctct tcaatgagct gccctctcgc aggatcacca aggaattcat tatggaaagt      600

gttcaggaag cagtagcctc caccagcggc accttagatg atgcagatga ccccagcacc      660

agtgttgggg cctatcacta catgctggag tcaaacatgg ggaagactat gctggagttt      720

caggagctga tgaccatttt ccaactattg cactggaatg gaagcctaaa agcccttcgt      780

gaaacaaagt gttcccgaca ggaagtcatc tcctactatt ctcagtattc tctagatgaa      840

aagatgcgca gccacatggc cctggactgg atcatgaagg agcgggactc accaggaatt      900

gtctctcaag agctacgaat ggccctgagg cagttggagg aagccaggaa agcaggacaa      960

gaactacggt tttacaaaga aaagaaagaa atattgagct tagccctgac tcagatctgc     1020

agtgaccctg acacttcctc acccagtgat gatcagctga gccttacggc cctgtgtggc     1080

tatcactagc aaggccaagc cccgggtacc ctcagtgatg gcagaggcca gattaacatt     1140

aggaatctca gtgcagaggt cctcagaggc tccagcatct ctagtactac ctgaaggctc     1200

tcctaaccct ctccacacat tccatttaca gagtatgaga gtcgtaggac ccttacaaga     1260

cccaacaagc cactcgatgc atttttctat cacattctca atagttccag ctcaggatga     1320

aaggatagac acaaaattgt ttgaaaaaca ttttccaggc ctggctccaa cctaaagcct     1380

gactgtcacg tgccttgctt gattttatat atattgtttc aagaatagtc caatatagca     1440

ttccccaaat gaacagcagc cagaattagg tgaagtagca tgatagcagt gtttaaaaat     1500

acttaggatt aaataaataa tatggattgt tttaaaaaat atccaaggat cagagtctct     1560

ttctaagctt tgtaagctaa gcaatagttt atgtcctact agatacactg caaactacag     1620

tggggatttt atctggacat cccaccatca aagatcttga aatagtaata gtatgaaaat     1680

actagataaa attaatgttt aaaatgtttt tgtaacaata atttttaaaa cccacactct     1740

tccatatatg gggataaata tcacctagaa aagtagcctc actcttattc ctcaagaatt     1800

aatatccaat gtttatgagt cttgcaatca attttgttca tttttaattt gcaaatcgat     1860

aacctgaact aatttgttct tattttttgc cactgcaaac atatatctac agagagaaaa     1920

attaatggca ttttaaaggt taaaacattt tgaaaaatta ttagcatgta acaaagaatg     1980

cttgcatttg attagtttca ccagcatttg agagaaggac cctttagctc tgtttgttgt     2040

tcaagaacat aagcaaccag tagctcaaat gtagtatcat tattaagttt aagtcactgg     2100

aatcttcttt aaaggaagga taagacattg ccatctctat ttaactcatc catatgggtc     2160

aatcaactga ttagaaaatc aaaaaacaat aaaaactttt tttttttttt tttttttagt     2220

agagacggga tttcatcatg ttgcccaggc tggtcttgaa ctcctgggct caagccatct     2280

gcctgcctcc acctcccaaa atgctgagat tacaggtgtg agccaccatg cctggcctaa     2340

actaattttt agatagttcc tggtcactca aatttaagaa tgtcagcaat gtcaatttta     2400

aatgctcata ggtctttcca tatctgtaac atgaaaatga ttattctgca ttttattcag     2460

tagtccaaat taaagaaaat gtttttctca atttaaaata atttcttttt cttttgttta     2520

tgcaagtgca tacatgcttc actgaaagca aaaccattat aattacatta aagtttataa     2580

aatatgatat tttaacctca tatctaataa gtatgtacaa aggtaaccat cactccttaa     2640

atccacatga aaactactgt aactgatcat gtattttgga attagacttg ataataaaag     2700

attatcatgt atcacatatc tcacaccagg ggaacaatta gctacataat tgtcatacct     2760

taatatcttt taaaggtaac agtaattttc aacacatttt attttaaaat attattttaa     2820

caaaagttac attcctctcc acaatgaggc taaatgtcac ccacgaaaga actttattcc     2880

cttatattcc tgaaaagaaa tcagaattaa catttttatg ttgaataaat tttaaaattt     2940

aggaaatgtt ctatttaaag ttaatttctt tcataaagcc attactcttt acattgtcat     3000

ttccaaaaag ccacaatttc ccatgctgga tgtgatgaaa gttaggcaca cctttactgc     3060

attagcagcc tttgacaatg acttcctcaa actgacacca tcttaattag atgcagggac     3120

agggatcaga tgggacaata tcaaatttac tttgtgccct acaagttaaa aactgcaccc     3180

attctgtaaa ttgaatatag aggttctccc ttggccactg tcagcttttc ttgactggcc     3240

aaaactgccc attcttcctg gaatggtatg aaagcttcag caaaataaat aaaagtcaga     3300

atctttgctg gtccctttaa tgctgatttg atagtaaatc aatttcagct gagacataag     3360

ggctgtcagt ctatcatata aacatcttta actatagcct agagaaaaga gggttgaaga     3420

gcaaagcaga tttttttttt ccttttctat atcttgttct gaacaacaca ctgtgataaa     3480

ggggactaga gtggaagatt ccctatttaa acacatgaag ctctgggtcc tagccttttt     3540

tggttataag ccctttgaga atctgataaa agctgtggat catctcctag gaaaatagaa     3600

caaaacatac atattcacat tacacagttc cagagtatgt ggacccccca aagtccagag     3660

attgccctag gggatcttta gattcttgtt tagaactgtt gattttgaac acaacataca     3720

ctgtcaaact ttacatcagg gatccaacat aactcagaca tagcccaggt agcctgtttc     3780

taacacaact gtcataatcc tgaaatccaa aattgcactg tgtttgacat gagatagttt     3840

aagttccaca aaatccaaat ttaccatatt attgttttta aaaaagcagt ttagagcaaa     3900

ctgtcactaa acttggataa atgggtcaga aagtacagat ttaataaagt cgtacctcta     3960

atgttcaaaa aaaaaaaaa                                                  3979


<210>  1814
<211>  9648
<212>  DNA
<213>  homo sapiens

<400>  1814
atggcccata acgcgggcgc cgcggccgcc gccggcaccc acagcgccaa gagcggcggc       60

tccgaggcgg ctctcaagga gggtggaagc gccgccgcgc tgtcctcctc ctcctcctcc      120

tccgcggcgg cagcggcggc atcctcttcc tcctcgtcgg gcccgggctc ggccatggag      180

acggggctgc tccccaacca caaactgaaa accgttggcg aagcccccgc cgcgccgccc      240

caccagcagc accaccacca ccaccatgcc caccaccacc accaccatgc ccaccacctc      300

caccaccacc acgcactaca gcagcagcta aaccagttcc agcagcagca gcagcagcag      360

caacagcagc agcagcagca gcagcaacag caacatccca tttccaacaa caacagcttg      420

ggcggcgcgg gcggcggcgc gcctcagccc ggccccgaca tggagcagcc gcaacatgga      480

ggcgccaagg acagtgctgc gggcggccag gccgaccccc cgggcccgcc gctgctgagc      540

aagccgggcg acgaggacga cgcgccgccc aagatggggg agccggcggg cggccgctac      600

gagcacccgg gcttgggcgc cctgggcacg cagcagccgc cggtcgccgt gcccgggggc      660

ggcggcggcc cggcggccgt cccggagttt aataattact atggcagcgc tgcccctgcg      720

agcggcggcc ccggcggccg cgctgggcct tgctttgatc aacatggcgg acaacaaagc      780

cccgggatgg ggatgatgca ctccgcctcc gccgccgccg ccggggcccc cggcagcatg      840

gaccccctgc agaactccca cgaagggtac cccaacagcc agtgcaacca ttatccgggc      900

tacagccggc ccggcgcggg cggcggcggc ggcggcggcg gcggaggagg aggaggcagc      960

ggaggaggag gaggaggagg aggagcagga gcaggaggag caggagcggg agctgtggcg     1020

gcggcggccg cggcggcggc ggcagcagca ggaggcggcg gcggcggcgg ctatgggggc     1080

tcgtccgcgg ggtacggggt gctgagctcc ccccggcagc agggcggcgg catgatgatg     1140

ggccccgggg gcggcggggc cgcgagcctc agcaaggcgg ccgccggctc ggcggcgggg     1200

ggcttccagc gcttcgccgg ccagaaccag cacccgtcgg gggccacccc gaccctcaat     1260

cagctgctca cctcgcccag ccccatgatg cggagctacg gcggcagcta ccccgagtac     1320

agcagcccca gcgcgccgcc gccgccgccg tcgcagcccc agtcccaggc ggcggcggcg     1380

ggggcggcgg cgggcggcca gcaggcggcc gcgggcatgg gcttgggcaa ggacatgggc     1440

gcccagtacg ccgctgccag cccggcctgg gcggccgcgc aacaaaggag tcacccggcg     1500

atgagccccg gcacccccgg accgaccatg ggcagatccc agggcagccc aatggatcca     1560

atggtgatga agagacctca gttgtatggc atgggcagta accctcattc tcagcctcag     1620

cagagcagtc cgtacccagg aggttcctat ggccctccag gcccacagcg gtatccaatt     1680

ggcatccagg gtcggactcc cggggccatg gccggaatgc agtaccctca gcagcaggac     1740

tctggagatg ccacatggaa agaaacattc tggttgatgc cacctcagta tggacagcaa     1800

ggtgtgagtg gttactgcca gcagggccaa cagccatatt acagccagca gccgcagccc     1860

ccgcacctcc caccccaggc gcagtatctg ccgtcccagt cccagcagag gtaccagccg     1920

cagcaggaca tgtctcagga aggctatgga actagatctc aacctcctct ggcccccgga     1980

aaacctaacc atgaagactt gaacttaata cagcaagaaa gaccatcaag tttaccagat     2040

ctgtctggct ccattgatga cctccccacg ggaacggaag caactttgag ctcagcagtc     2100

agtgcatccg ggtccacgag cagccaaggg gatcagagca acccggcgca gtcgcctttc     2160

tccccacatg cgtcccctca tctctccagc atcccggggg gcccatctcc ctctcctgtt     2220

ggctctcctg taggaagcaa ccagtctcga tctggcccaa tctctcctgc aagtatccca     2280

ggtagtcaga tgcctccgca gccacccggg agccagtcag aatccagttc ccatcccgcc     2340

ttgagccagt caccaatgcc acaggaaaga ggttttatgg caggcacaca aagaaaccct     2400

cagatggctc agtatggacc tcaacagaca ggaccatcca tgtcgcctca tccttctcct     2460

gggggccaga tgcatgctgg aatcagtagc tttcagcaga gtaactcaag tgggacttac     2520

ggtccacaga tgagccagta tggaccacaa ggtaactact ccagaccccc agcgtatagt     2580

ggggtgccca gtgcaagcta cagcggccca gggcccggta tgggtatcag tgccaacaac     2640

cagatgcatg gacaagggcc aagccagcca tgtggtgctg tgcccctggg acgaatgcca     2700

tcagctggga tgcagaacag accatttcct ggaaatatga gcagcatgac ccccagttct     2760

cctggcatgt ctcagcaggg agggccagga atggggccgc caatgccaac tgtgaaccgt     2820

aaggcacagg aggcagccgc agcagtgatg caggctgctg cgaactcagc acaaagcagg     2880

caaggcagtt tccccggcat gaaccagagt ggacttatgg cttccagctc tccctacagc     2940

cagcccatga acaacagctc tagcctgatg aacacgcagg cgccgcccta cagcatggcg     3000

cccgccatgg tgaacagctc ggcagcatct gtgggtcttg cagatatgat gtctcctggt     3060

gaatccaaac tgcccctgcc tctcaaagca gacggcaaag aagaaggcac tccacagccc     3120

gagagcaagt caaagaagtc cagctcctcc accactactg gggagaagat cacgaaggtg     3180

tacgagctgg ggaatgagcc agagagaaag ctctgggtcg accgatacct caccttcatg     3240

gaagagagag gctctcctgt ctcaagtctg cctgccgtgg gcaagaagcc cctggacctg     3300

ttccgactct acgtctgcgt caaagagatc gggggtttgg cccaggttaa taaaaacaag     3360

aagtggcgtg agctggcaac caacctaaac gttggcacct caagcagtgc agcgagctcc     3420

ctgaaaaagc agtatattca gtacctgttt gcctttgagt gcaagatcga acgtggggag     3480

gagcccccgc cggaagtctt cagcaccggg gacaccaaaa agcagcccaa gctccagccg     3540

ccatctcctg ctaactcggg atccttgcaa ggcccacaga ccccccagtc aactggcagc     3600

aattccatgg cagaggttcc aggtgacctg aagccaccta ccccagcctc cacccctcac     3660

ggccagatga ctccaatgca aggtggaaga agcagtacaa tcagtgtgca cgacccattc     3720

tcagatgtga gtgattcatc cttcccgaaa cggaactcca tgactccaaa cgccccctac     3780

cagcagggca tgagcatgcc cgatgtgatg ggcaggatgc cctatgagcc caacaaggac     3840

ccctttgggg gaatgagaaa agtgcctgga agcagcgagc cctttatgac gcaaggacag     3900

atgcccaaca gcagcatgca ggacatgtac aaccaaagtc cctccggagc aatgtctaac     3960

ctgggcatgg ggcagcgcca gcagtttccc tatggagcca gttacgaccg aaggcatgaa     4020

ccttatgggc agcagtatcc aggccaaggc cctccctcgg gacagccgcc gtatggaggg     4080

caccagcccg gcctgtaccc acagcagccg aattacaaac gccatatgga cggcatgtac     4140

gggcccccag ccaagcgcca cgagggcgac atgtacaaca tgcagtacag cagccagcag     4200

caggagatgt acaaccagta tggaggctcc tactcgggcc cggaccgcag gcccatccag     4260

ggccagtacc cgtatcccta cagcagggag aggatgcagg gcccggggca gatccagaca     4320

cacggaatcc cgcctcagat gatgggcggc ccgctgcagt cgtcctccag tgaggggcct     4380

cagcagaata tgtgggcagc acgcaatgat atgccttatc cctaccagaa caggcagggc     4440

cctggcggcc ctacacaggc gcccccttac ccaggcatga accgcacaga cgatatgatg     4500

gtacccgatc agaggataaa tcatgagagc cagtggcctt ctcacgtcag ccagcgtcag     4560

ccttatatgt cgtcctcagc ctccatgcag cccatcacac gcccaccaca gccgtcctac     4620

cagacgccac cgtcactgcc aaatcacatc tccagggcgc ccagcccagc gtccttccag     4680

cgctccctgg agaaccgcat gtctccaagc aagtctcctt ttctgccgtc tatgaagatg     4740

cagaaggtca tgcccacggt ccccacatcc caggtcaccg ggccaccacc ccaaccaccc     4800

ccaatcagaa gggagatcac ctttcctcct ggctcagtag aagcatcaca accagtcttg     4860

aaacaaaggc gaaagattac ctccaaagat atcgttactc ctgaggcgtg gcgtgtgatg     4920

atgtccctta aatcaggtct tttggctgag agtacgtggg ctttggacac tattaatatt     4980

cttctgtatg atgacagcac tgttgctact ttcaatctct cccagttgtc tggatttctc     5040

gaacttttag tcgagtactt tagaaaatgc ctgattgaca tttttggaat tcttatggaa     5100

tatgaagtgg gagaccccag ccaaaaagca cttgatcaca acgcagcaag gaaggatgac     5160

agccagtcct tggcagacga ttctgggaaa gaggaggaag atgctgaatg tattgatgac     5220

gacgaggaag acgaggagga tgaggaggaa gacagcgaga agacagaaag cgatgaaaag     5280

agcagcatcg ctctgactgc cccggacgcc gctgcagacc caaaggagaa gcccaagcaa     5340

gccagtaagt tcgacaagct gccaataaag atagtcaaaa agaacaacct gtttgttgtt     5400

gaccgatctg acaagttggg gcgtgtgcag gagttcaata gtggccttct gcactggcag     5460

ctcggcgggg gtgacaccac cgagcacatt cagactcact ttgagagcaa gatggaaatt     5520

cctcctcgca ggcgcccacc tcccccctta agctccgcag gtagaaagaa agagcaagaa     5580

ggcaaaggcg actctgaaga gcagcaagag aaaagcatca tagcaaccat cgatgacgtc     5640

ctctctgctc ggccaggggc attgcctgaa gacgcaaacc ctgggcccca gaccgaaagc     5700

agtaagtttc cctttggtat ccagcaagcc aaaagtcacc ggaacatcaa gctgctggag     5760

gacgagccca ggagccgaga cgagactcct ctgtgtacca tcgcgcactg gcaggactcg     5820

ctggctaagc gatgcatctg tgtgtccaat attgtccgta gcttgtcatt cgtgcctggc     5880

aatgatgccg aaatgtccaa acatccaggc ctggtgctga tcctggggaa gctgattctt     5940

cttcaccacg agcatccaga gagaaagcga gcaccgcaga cctatgagaa agaggaggat     6000

gaggacaagg gggtggcctg cagcaaagat gagtggtggt gggactgcct cgaggtcttg     6060

agggataaca cgttggtcac gttggccaac atttccgggc agctagactt gtctgcttac     6120

acggaaagca tctgcttgcc aattttggat ggcttgctgc actggatggt gtgcccgtct     6180

gcagaggcac aagatccctt tccaactgtg ggacccaact cggtcctgtc gcctcagaga     6240

cttgtgctgg agaccctctg taaactcagt atccaggaca ataatgtgga cctgatcttg     6300

gccactcctc catttagtcg tcaggagaaa ttctatgcta cattagttag gtacgttggg     6360

gatcgcaaaa acccagtctg tcgagaaatg tccatggcgc ttttatcgaa ccttgcccaa     6420

ggggacgcac tagcagcaag ggccatagct gtgcagaaag gaagcattgg aaacttgata     6480

agcttcctag aggatggggt cacgatggcc cagtaccagc agagccagca caacctcatg     6540

cacatgcagc ccccgcccct ggaaccacct agcgtagaca tgatgtgcag ggcggccaag     6600

gctttgctag ccatggccag agtggacgaa aaccgctcgg aattcctttt gcacgagggc     6660

cggttgctgg atatctcgat atcagctgtc ctgaactctc tggttgcatc tgtcatctgt     6720

gatgtactgt ttcagattgg gcagttatga cataagtgag aaggcaagca tgtgtgagtg     6780

aagattagag ggtcacatat aactggctgt tttctgttct tgtttatcca gcgtaggaag     6840

aaggaaaaga aaatctttgc tcctctgccc cattcactat ttaccaattg ggaattaaag     6900

aaataattaa tttgaacagt tatgaaatta atatttgctg tctgtgtgta taagtacatc     6960

ctttggggtt ttttttttct ctttttttta accaaagttg ctgtctagtg cattcaaagg     7020

tcactttttg ttcttcacag atctttttaa tgttctttcc catgttgtat tgcatttttg     7080

ggggaagcaa attgacttta aagaaaaaag ttgtggcaaa agatgctaag atgcgaaaat     7140

ttcaccacac tgagtcaaaa aggtgaaaaa ttatccattt cctatgcgtt ttactcctca     7200

gagaatgaaa aaaactgcat cccatcaccc aaagttctgt gcaatagaaa tttctacaga     7260

tacaggtata ggggctcaag gaggtatgtc ggtcagtagt caaaactatg aaatgatact     7320

ggtttctcca caggaatatg gttccattag gctgggagca aaaacaatgt tttttaagat     7380

tgagaataca tacctgacaa cgatccggaa actgctcctc accactcccg tcatgcctgc     7440

tgtcggcgtt tgaccttcca cgtgacagtt cttcacaatt cctttcatca ttttttaaat     7500

atttttttta ctgcctatgg gctgtgatgt atatagaagt tgtacattaa acataccctc     7560

atttttttct tttctttttt tttttttttt ttagtacaaa gttttagttt ctttttcatg     7620

atgtggtaac tacgaagtga tggtagattt aaataatttt ttatttttat tttatatatt     7680

ttttcattag ggccatatct ccaaaaaaag aaagaaaaaa tacaaaaaac aaaaacaaaa     7740

aaaaaagagg gtaatgtaca agtttctgta tgtataaagt catgctcgat ttcaggagag     7800

cagctgatca caatttgctt catgaatcaa ggtgtggaaa tggttatata tggattgatt     7860

tagaaaatgg ttaccagtac agtcaaaaaa gagaaaatga aaaaaataca actaaaagga     7920

agaaacacaa cttcaaagat ttttcagtga tgagaatcca catttgtatt tcaagataat     7980

gtagtttaaa aaaaaaaaaa agaaaaaaac ttgatgtaaa ttcctccttt tcctctggct     8040

taatgaatat catttattca gtataaaatc tttatatgtt ccacatgtta agaataaatg     8100

tacattaaat cttgttaagc actgtgatgg gtgttcttga atactgttct agtttcctta     8160

aagtggtttc ctagtaatca agttatttac aagaaatagg ggaatgcagc agtgtattca     8220

cattataaaa ccctacattt ggaagagacc tttaggggtt acctacttta gagtggggag     8280

caacagtttg attttctcaa attacttagc taattagtct ttctttgaag caattaactc     8340

taacgacatt gaggtatgat cattttcagt atttatggga ggtggctgct gacccacttg     8400

aggtgagatc tcagaagctt aactggcctg aaaatgtaac attctgcctt ttactaactc     8460

catcttagtt taatcaaagt tcaatctatt ccttgtttct tctgtgtgcc tcagagttat     8520

tttgcattta gtttactcca ccgtgtataa tatttatact gtgcaatgtt aaaaaagaat     8580

ctgttatatt gtatgtggtg tacatagtgc aaagtgatga tttctatttc agggcatatt     8640

atggttctca tattccttcc tacctggtgc acagtagctt tttaatacta gtcacttcta     8700

atttaaactt tctcttcctg ggtcattgac tgttactgtg taataatcga tttctttgaa     8760

actgctgcat aattatgctg ttagtggacc tctacctctt ctcttccctc tcccaatcac     8820

agtatactca gaatccccag cccctcgcat acattgtgtc ggttcacatt actcacagta     8880

atatatggaa gagttagaca agaacatgca gttacagtca ttgtgagacg tgactctcca     8940

gtgtcacgag gaaaaaaatc atcttttctg caaacagtct ctcatctgtc aactcccaca     9000

ttactgagtc aaacagtctt cttacataac aatgcaacca aatatatgtt gaattaaaga     9060

cccatttata attctgcttt aaatacatct gcttgctaag aacagatttc agtgctccaa     9120

gcttcaaata tggagatttg taagagggaa ttcaatatta ttctaatttc tctcttacag     9180

agtacaaata aaaggtgtat acaaactccg aacatatcca gtattccaat tcctttgtca     9240

atcagaagag taaaataatt aacaaaagac tgttgttatg gtttgcattg taaccgatac     9300

gcagagtctg accgttgggc aacaagtttt tctatcctga tgcgcaacac agtctctaga     9360

gactaatcca ggaagacttt agcctccttt ccatattctc acccccgaat caagatttac     9420

agaagcccac gaagaattta cagcctgctt gagatcatct tgcctataaa ctgagttatt     9480

gctttgtcct aaaaattagt cggttttttt ttttctatga ggcttttcag aaatttacag     9540

gatgcccaga ctttacatgt gtaccaaaaa aaaaaaaaag ataaaaaata aaggtgcaaa     9600

gaaagtttag tattttggaa tggtgctata aagttgaaaa aaaaaaaa                  9648


<210>  1815
<211>  4225
<212>  DNA
<213>  homo sapiens

<400>  1815
gcagagggtg cggcccagag gaggccgcgg gccgggaagg gccgggcggg acgggaaacg       60

ttagggcagc ggcccccggg gtgagggggc cgagcggacg ggcagggccc cgaggcgaac      120

tctgcccgga tgaggaacaa agcagtgggg caggcgcgtg cgcccccagc gcagctggca      180

ggttgggcag cccccttccc gaagcttctg gacggaaggc cccaggtgtt ccccgagatg      240

ccccaacccg tggcggggtg cacggccacc ggccctcggg agaagttggg cggccccggg      300

cgaccccggg gacgagtggc cgcgtcggtg cagcggttgt gagcaagatg tggtagcacg      360

tgaccctgga acgcaaaccc tgatgcctgt tccccaccac ccgagcgctc ctttctctga      420

tatttggccc caagccgatg catcacagga tgaatgaaat gaacctgagt ccagtgggga      480

tggagcagct gacttcatcc tctgtgagca atgccttgcc agtctcagga agtcacctgg      540

gattggctgc ctcacccact cacagtgcca tccctgcccc aggcctccca gtggcaattc      600

caaacctggg tccctccctg agctctctgc cttctgctct gtctttaatg ctaccaatgg      660

gtattgggga tcgaggggtg atgtgtgggt tacctgaaag aaactacacc ctacctccac      720

caccttaccc tcacctggag agcagttatt tcagaaccat tctacctggc attttatctt      780

atttagctga cagaccacct ccacagtaca tccaccctaa ctctataaat gttgatggta      840

atacagcatt atctatcacc aataaccctt cagcactaga tccctatcag tccaatggaa      900

atgttggatt agaaccaggc attgtttcaa tagactctcg ctctgtgaac acacatggtg      960

cccaaagtct tcatcccagt gatggccatg aggtggcctt ggacacagca atcactatgg     1020

agaacgtttc tagggttacc agcccaattt cgacagatgg aatggcagag gagcttacga     1080

tggacggtgt tgcaggcgag cattcccaaa tcccaaatgg ctccagaagt catgaacctc     1140

tgtctgtgga ttctgtgagc aacaaccttg cagcagacgc tgtaggacat ggtggtgtga     1200

tacccatgca tgggaatggc ctggagctcc ctgtggtcat ggagacagac cacattgcaa     1260

gtcgggtcaa tggcatgtct gacagtgccc tcagtgactc cattcacact gtggccatga     1320

gcaccaactc tgtaagcgtg gcactctcta cctcacacaa ccttgcctcc ctagaatctg     1380

tttccctcca tgaagttggc ctcagcctag aacctgtggc tgtctcctcc atcacccagg     1440

aggttgctat ggggacaggt catgtagatg tatcttcaga cagtctttct tttgtatcac     1500

cttcactgca aatggaagac tccaattcaa acaaggagaa catggcaacc ttgtttacaa     1560

tttggtgtac tctgtgtgac cgcgcctatc cctcggactg tcccgaacat ggaccagtga     1620

cttttgttcc tgacactcca atagagagca gagcaaggct ttctctccca aagcagcttg     1680

ttctccgtca gtcaattgtg ggagcagaag ttggtgtatg gactggagaa accattcctg     1740

tgcggacttg ctttggacct ctaattggcc agcagagtca ctccatggaa gtagcagaat     1800

ggacagacaa ggcagttaac catatctgga agatatacca caatggtgtc ctagaattct     1860

gcatcattac aactgatgaa aatgaatgta attggatgat gtttgtgcgc aaagccagga     1920

accgggaaga gcagaatttg gtggcttatc ctcatgatgg aaaaatcttt ttctgcacct     1980

cacaagatat ccctcctgaa aatgaactgc ttttttatta tagccgagat tatgctcaac     2040

agattggtgt tcctgaacac ccagatgtgc atctctgtaa ctgtggcaag gagtgcaatt     2100

cttacacaga gttcaaagcc catctgacca gccacatcca taaccatctt cctacccagg     2160

gacatagcgg cagccatggg ccaagtcaca gcaaagaaag gaagtggaag tgctcaatgt     2220

gcccccaagc ttttatctct ccttccaaac ttcatgtcca ctttatgggt cacatgggta     2280

tgaagcccca caagtgtgat ttctgtagca aggcttttag tgatcccagc aacctgcgga     2340

cccacctcaa gatacataca ggtcagaaga actacaggtg taccttgtgt gacaagtctt     2400

tcacccagaa ggctcacctg gagtcccaca tggttatcca cactggggag aagaatctta     2460

agtgtgatta ctgtgacaag ttgtttatgc ggaggcagga cctcaagcag cacgtgctca     2520

tccacactca agaacgccag atcaagtgtc ccaagtgtga taagctgttc ttgagaacaa     2580

atcacttaaa gaagcatctc aattctcatg aaggaaaacg ggattatgtc tgtgaaaaat     2640

gtacaaaggc ttatctaacc aaataccatc tcacccgcca cctgaaaacc tgcaaagggc     2700

ccacctccag ttcgtcagca ccagaggagg aagaagagga tgactcagaa gaggaagatc     2760

tagcagactc tgtggggaca gaagactgta ggattaacag tgctgtgtat tcagcggatg     2820

agtctctttc tgcacataaa taaaaggaaa agaaacaagc aattttggat gaaaatgcaa     2880

atggaaaaat acacataacc agttatctac tataatggtt tttatataaa atggttcctg     2940

atttattttc agccagtaat caaaacagac tgggaatgaa taaagcactt acagaagagt     3000

atcctaatga aaacacttta aaacagattg ggaaaactga gcatgtgtcc tgttttaagt     3060

ggtggactgg gagggaagtg tcaacttctg aggtctttat ttacatgata atctgggaga     3120

tgcatttatg cctgaatcaa agctgccttc tgctcaaaca aatcagattt atttcacatt     3180

cttccattat tccattttcc tgctggtcct gtgacttggt aacattctaa acggtccttg     3240

ccccatagcc atcctgattg ctgatagtgt tttatgcaga ctcttgtgac ttatactcac     3300

cacagaatgg attgggacac agcagcataa gtgtgctact tggcagctag taagtttaaa     3360

gcaggacctg ccttaactgc tcctggccac ttggaagttt agggtagatc ttgttttcca     3420

aagtttcggc aggtgcctgg agggcaaata aaaaagcagc agtcagtcag tagtcagtga     3480

tggagagaac aagaggagag atgcctggcc tctgcccaag aaattagctt tgatggaagc     3540

ctgagcaagt cacctggtta ttgtaacgtg gagatctttg taggtttaga catggctccc     3600

tgtctccagt aaacatccag ccattcagac aaagggggcc tggagataca gagagcccaa     3660

ataatgcctg ctggattgtc tcctgatgag tacatgtgga ctcacctgag gaagggaagg     3720

aagggaataa tcttttatgt ttcatttacc ttatgaaaag tgttaaaaca ttgccaactc     3780

aaaataacat tatttaatgc atgtgcaaag ttaggtcttc ccagttgtct cagtgctgag     3840

gaacctcatc agagaagcat ggaagatgcc aaaggatttt tggaaggtaa agaaggctga     3900

atagtgacca catgggcctg ttttcagggt cccagcttag ttaagtcacc catgcacctg     3960

gtcattgtgt ctcccatgca catccagcgt ttctcagaag cagacccacc cttaagttga     4020

caggattgat ggaacatgct ctcctgctca aggcacaacc tctgggctgg agtagaggac     4080

tctggtggga aggttttgct gctaatgtat ttatggaatg aatgtatttc attcaaatct     4140

gtattcctct aggaaggatt aaaattaaac ttttttaaaa tacaggaaaa aaaaaaaaaa     4200

aaaaaaaaaa aaaaaaaaaa aaaaa                                           4225


<210>  1816
<211>  1661
<212>  DNA
<213>  homo sapiens

<400>  1816
tcgccaagcg actaaagctg gaagggaggg ggcggggttg tgagcaaatc ttggtggtgg       60

tggtggtggg gcggcctgag aagatatcat ggctgctgcc acggagctta atcgcccgag      120

cagcggtgac aggaacctgg agcgaagatg cagacccaac ctctcccgag aggtgctcta      180

cgaaatcttt cgctccctac acaccctggt tggacagctt gacctcagag atgatgtggt      240

gaaaattaca atcgattgga acaagctcca gagcctctcg gcattccagc ctgcattgct      300

ctttagtgca cttgaacaac acattttata tttacagcct tttttagcaa aacttcagtc      360

tccgattaaa gaggagaata caactgctgt tgaagagata ggaagaacag aaatggggaa      420

caaaaatgaa gtaaatgaca aattttccat tggcgaccta caagaggaag aaaagcacaa      480

agaaagtgat ttaagagatg tgaaaaagac acagatccat tttgatccag aagtagttca      540

gataaaggct ggaaaagcag aaattgacag acgaatatct gcatttattg aaagaaagca      600

agctgaaatc aatgaaaaca acgtcaggga attttgcaat gttattgatt gtaatcaaga      660

aaatagttgt gcaagaactg atgcgatttt taccccttac cccggattta aaagtcacgt      720

aaaagtttct agagttgtga atacatacgg accacagact agacctgaag gaattccagg      780

gtcaggtcat aaacctaaca gcatgcttcg agactgtggt aatcaggctg tagaagaacg      840

actacaaaat attgaggccc acttgcggtt acagacaggt ggtccagtgc caagagacat      900

ttatcagaga attaaaaaac ttgaggataa aatccttgaa ttggaaggca tctctcctga      960

atattttcag tctgtaagct tttctggaaa aagaagaaaa gttcaaccac ctcaacagaa     1020

ctattcactg gctgaacttg atgagaaaat tagtgccctc aaacaagccc tcctcagaaa     1080

atcaagagaa gcagaatcca tggcaaccca ccaccttcca tgaaaaactc ctctcatcct     1140

tgtcatttta cttttttgta tacatatgtg taacttacac tgttattaat tcaacggata     1200

tatatttatc aatgtagact tctctgtgaa gtcaaggttt attttcacat gagtccagct     1260

tgcagcaagt aatcttcaaa tattccagta agttttgaaa taatgaatgc attgaaaata     1320

gcattgttgg aatttattcc cttctgtttt aaaggaggta ttttggaaat tgaaaaactt     1380

aatttacaag tgctggtaca tcttttttct tttgtggacc acaggaagga agatttattt     1440

tgatattgat actttaaaag gactttatat ttgtaacatt gatgttaacc agtttattag     1500

tttaaatcag tactttgcat ataataagca ttcaacaaaa atttattgac tgaaatgaat     1560

tttaaatgca tgtgtatgaa cttgtttttc ttaatcttta agatgtcagt attcatgtaa     1620

ataaacaata gatccagctt tatcccttaa aaaaaaaaaa a                         1661


<210>  1817
<211>  1958
<212>  DNA
<213>  homo sapiens

<400>  1817
cagctgccta tcggcttctc agtgtttgaa cttcaaaggg ctggacgctc acccaagaag       60

gggaccccgg cctgacctct ctcggaattc aaaaaaatct aaggctcaga gagggaatgg      120

gagctggctc ttccctctgt gtttagcatc cacgtttttt ggcggtctgg ctgaaaccag      180

cccaccctag ttcgggcgcc agagcaacgc agttccgagg gcagatctcc aaggggcgga      240

ggcagagccg cgggcccttc caccgcagcc atccgcacgg gaggcctcgc gattgctcgg      300

aaccatcccg caggagttca gctgatattt tctagtgtgg ggcgagagat tttgtggagc      360

gcatttaagg ggtttttgtt gtgactgctg ccttgtatat atttattttc tttcttggaa      420

ctgggcctcg ccctcctccc actgacatga tggcccagtc caaggccaat ggctcgcact      480

atgcgctgac cgccatcggc ctggggatgc tggtccttgg ggtgatcatg gccatgtgga      540

acctggtacc cggcttcagc gcggccgaga agccaacagc tcagggcagc aacaagaccg      600

aggtgggtgg cggcatcctc aagagcaaga ccttctctgt ggcctacgtg ctggtcgggg      660

ccggggtgat gctgctgctg ctttctatct gcctgagtat cagggataag aggaagcagc      720

ggcagggcga ggacctggcc catgtccagc acccgacagg cgctgggcct cacgcccagg      780

aggaagacag ccaggaggaa gaagaggagg atgaggaggc tgcctcaagg tactatgttc      840

ccagctacga ggaagtgatg aacacaaact actcagaagc aaggggagag gagcagaacc      900

cgaggttgag catctctctc ccgtcctatg agtcactgac ggggctcgac gagaccaccc      960

ccacatccac cagggctgac gtggaggcca gccctgggaa cccccctgac aggcagaact     1020

ctaagttggc caaacgactg aaaccgctga aagttcgaag gattaaatct gaaaagcttc     1080

acctcaaaga ctttaggatc aacctcccag acaaaaacgt ccctcctccc tcgatagagc     1140

ctttgactcc tccaccgcag tatgatgaag tccaggagaa ggcccccgac acccggccgc     1200

ccgactgaat ggccccactt gagccacgct ccctcctgtc tctcacacct ttcaccccca     1260

agactctaac aaagccacat gagccacagt tgagaagcgg aggggccagc tgtgcatgga     1320

gccatttgga tggcggcggg cgggggggga ttctctgtat caggagtgac tttgttgccc     1380

cacacagcct cctgctgcag gtgctttgga aagagatgct gccttggagc tggtgaatct     1440

gtggaccaca ttcaagggtg tggcacaggc atcttcccat ccttttcact ccgaatcgct     1500

ggcgacacat tctcctttcc agctaggaaa gggttcctcg cggctggttt agattgtggt     1560

tgtttgtttt gcttctacta agactgtttt gtttcaaaaa ggaaacaagt tttgtgtttg     1620

ctgtctacgc tggagtcctg aactgtgggt agaaaacacg acctggcttt gtagaaagga     1680

cacagggctg ttttatgaac taagcggtga ggctcaggtg gcggctctcg cagagcccct     1740

gatgctgttg ttctttgagg gcttaaggcc tgatgaacgt aggcacgtga tgcataatag     1800

tcttcaatgg tacacttaac tagtctcttc tgtgtaacag caaaaaaaaa aaaaaaaaga     1860

agaagaaaga aaactgtagg aaatgttctt tttgaaatgc catgcaatgg agctttttgt     1920

aataaaatat tttatatgta gtaaaaaaaa aaaaaaaa                             1958


<210>  1818
<211>  2911
<212>  DNA
<213>  homo sapiens

<400>  1818
gcggccgcct ccccctcccc ctccccctct ttcttctcct ccctcgtcgc cgccgccgcc       60

gccgccgcct cagccttcgc ctcagccgcc gcccgctccc gcccgcgcgc ggcgggatgg      120

acgatcaatc caggatgctg cagactctgg ccggggtgaa cctggctggc cactcggtgc      180

aggggggcat ggccctgccg cctcccccgc acggccacga aggggcggac ggcgacggca      240

ggaagcagga catcggcgac atcctccacc agatcatgac catcaccgac cagagcttgg      300

acgaggcgca agcaaagaaa catgccctga actgtcacag aatgaaacca gcgctcttca      360

gcgtcctgtg tgagatcaaa gagaaaacag gtctcagcat cagaggagcc caggaggagg      420

accctcccga tccccagcta atgagactgg acaatatgct tttggcagaa ggggtttcag      480

gtcctgagaa aggtggggga tcggcggcag cagctgcagc cgcggcagcc tctggaggtt      540

cttcagataa ctctattgaa cactcagatt acagagccaa attgacccag atcagacaaa      600

tctatcacac agaactggag aaatatgaac aggcatgtaa tgaatttact acacatgtga      660

tgaaccttct ccgagaacag agtagaacac gtcccatttc tccaaaagag attgaaagaa      720

tggtgggcat catccatcga aaatttagtt ccattcagat gcagctcaaa caaagcactt      780

gtgaagcagt tatgatttta agatcaaggt tccttgatgc cagacggaaa aggcgtaact      840

tcagtaaaca ggccacagaa atcttgaatg aatattttta ctcacacctc agcaacccct      900

accccagtga agaagccaaa gaggagctgg ccaagaaatg cagcatcaca gtgtcacagg      960

tatccaattg gtttggcaac aaacgaatca ggtacaagaa gaacattggc aagtttcagg     1020

aagaagccaa cctctatgct gcaaagacgg ccgtgacagc tgcacacgca gtagcagcag     1080

ctgtgcagaa caaccagacc aattcgccca ccacaccaaa ttccggttct tctggttctt     1140

ttaacctccc aaattctggg gacatgttca tgaacatgca gagtctgaat ggggattctt     1200

accaagggtc ccaagtcgga gccaatgtgc aatcacaggt ggataccctc cgtcatgtta     1260

tcaatcagac gggaggctac agtgatggcc ttggaggaaa ttcactgtac agtccacata     1320

atttaaatgc taatggaggc tggcaggacg caacaactcc atcttctgtg acttctccta     1380

cagaaggccc aggaagtgtg cactcggata cctctaacta atctctggcc acacttttcc     1440

ctgagctaca tgccttgata agtgcattca gagcaatagg aggaaaagga aagcgttttt     1500

gtagcccacc atctacagct ttactgtaaa accttgtctt attcgagaac ttggtaaatc     1560

tgttttttaa ggaatcataa tcatttgtat ttatacttaa aaacacacaa tgttaaaaaa     1620

aataaagcac tttatccaat taggccaaga tttaacattg ttgacagtcc tgtagctatt     1680

ttatcataat ttattatcaa tattttacat taatggtttc acagttgcca attacttggc     1740

cttaagggta aaaagtacaa tatacactaa acctcaaccg ttaaagcaga tgcaaaaatt     1800

cacctcacct aaattgaact tcttgcatat ttccattact gacttggatt gtctttcttt     1860

catatcacta atggagttgg aataaagagc tgtttgccta tccctgttaa tgatggttgt     1920

gtttaagaat cttcctcgtc acgtttgtgt tcagatctct tatgttataa ttagatcaga     1980

gactggtagc atcgtttctc tctctgaaag caccagtgcc cagagtctgc tcggtaataa     2040

aattatggat ccagattgtt ctgagagacg aagatacttg ctgctgatag aggtgaaaac     2100

gagattgatc cgtctggggt tttacggtgt gcactgggtg ctgcacagac ttgtcaaggt     2160

ttgctacgtc ctctgggcat ctgcaaaagg ccctgctctc tggagtgttg tatatagtgt     2220

agcaaaagag tatttataca tcccaccaat caaaacacag ctttattacc tcatgcgaac     2280

tcatacaaac caatagaatt tcaacatgtt ctgtagctta gagtgctcac ttactacctc     2340

tgaacaatac tcacgctgta gtttgtctct ttcttatctt tttgcatctt gtaattaact     2400

ctttgtttcc cttcataaaa tgtaatgtac attgtaatct tttaaaagaa aaatcagggt     2460

tgcacttgca acttttaaaa aaccgagtgt ggaaacattg ggtcttaatt caacacagga     2520

tcggtaaaac tgttgtaaat actgagaaac attttgaatg ttcttcatct tattactaat     2580

ccatgcaaaa aaaaaaaaaa aagcagcgac taattgtgat gcattcagat ttcagtattc     2640

agtactgtat atttcaccct gtgtaatggg gccccctctc ctttctctct ttttgtattg     2700

tatgcgattc tgaaactgat tgagtcatga aaataatttg tggcggtgat tctaatgtat     2760

taaaaacgtt tcgtgttcct ttctaactgg attacaccct ggattgaaaa agtcttcctc     2820

gtggtagtta tatgtagttt caaacatgaa taaacttttt gctttcatga ttaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                                    2911


<210>  1819
<211>  2825
<212>  DNA
<213>  homo sapiens

<400>  1819
ctctgcacag gagcggacgc gggagcccct ccgcacccgt cccctccccc gggtcgcctt       60

cgcctgcccc cggggcgagg ctccccgcgc gggttcgcgt cgcgtctgca gtggccgagg      120

ctgctgcctg ccgggcagat gggtccgcct tgttccggct gcagctttcg ccgccggggc      180

ttgctggctg tcgggaacta gtcaactgga gtttttgttg acttcccacg gaaacatgcc      240

ctgaactgtc acagaatgaa accagcgctc ttcagcgtcc tgtgtgagat caaagagaaa      300

acaggtctca gcatcagagg agcccaggag gaggaccctc ccgatcccca gctaatgaga      360

ctggacaata tgcttttggc agaaggggtt tcaggtcctg agaaaggtgg gggatcggcg      420

gcagcagctg cagccgcggc agcctctgga ggttcttcag ataactctat tgaacactca      480

gattacagag ccaaattgac ccagatcaga caaatctatc acacagaact ggagaaatat      540

gaacaggcat gtaatgaatt tactacacat gtgatgaacc ttctccgaga acagagtaga      600

acacgtccca tttctccaaa agagattgaa agaatggtgg gcatcatcca tcgaaaattt      660

agttccattc agatgcagct caaacaaagc acttgtgaag cagttatgat tttaagatca      720

aggttccttg atgccagacg gaaaaggcgt aacttcagta aacaggccac agaaatcttg      780

aatgaatatt tttactcaca cctcagcaac ccctacccca gtgaagaagc caaagaggag      840

ctggccaaga aatgcagcat cacagtgtca caggtatcca attggtttgg caacaaacga      900

atcaggtaca agaagaacat tggcaagttt caggaagaag ccaacctcta tgctgcaaag      960

acggccgtga cagctgcaca cgcagtagca gcagctgtgc agaacaacca gaccaattcg     1020

cccaccacac caaattccgg ttcttctggt tcttttaacc tcccaaattc tggggacatg     1080

ttcatgaaca tgcagagtct gaatggggat tcttaccaag ggtcccaagt cggagccaat     1140

gtgcaatcac aggtggatac cctccgtcat gttatcaatc agacgggagg ctacagtgat     1200

ggccttggag gaaattcact gtacagtcca cataatttaa atgctaatgg aggctggcag     1260

gacgcaacaa ctccatcttc tgtgacttct cctacagaag gcccaggaag tgtgcactcg     1320

gatacctcta actaatctct ggccacactt ttccctgagc tacatgcctt gataagtgca     1380

ttcagagcaa taggaggaaa aggaaagcgt ttttgtagcc caccatctac agctttactg     1440

taaaaccttg tcttattcga gaacttggta aatctgtttt ttaaggaatc ataatcattt     1500

gtatttatac ttaaaaacac acaatgttaa aaaaaataaa gcactttatc caattaggcc     1560

aagatttaac attgttgaca gtcctgtagc tattttatca taatttatta tcaatatttt     1620

acattaatgg tttcacagtt gccaattact tggccttaag ggtaaaaagt acaatataca     1680

ctaaacctca accgttaaag cagatgcaaa aattcacctc acctaaattg aacttcttgc     1740

atatttccat tactgacttg gattgtcttt ctttcatatc actaatggag ttggaataaa     1800

gagctgtttg cctatccctg ttaatgatgg ttgtgtttaa gaatcttcct cgtcacgttt     1860

gtgttcagat ctcttatgtt ataattagat cagagactgg tagcatcgtt tctctctctg     1920

aaagcaccag tgcccagagt ctgctcggta ataaaattat ggatccagat tgttctgaga     1980

gacgaagata cttgctgctg atagaggtga aaacgagatt gatccgtctg gggttttacg     2040

gtgtgcactg ggtgctgcac agacttgtca aggtttgcta cgtcctctgg gcatctgcaa     2100

aaggccctgc tctctggagt gttgtatata gtgtagcaaa agagtattta tacatcccac     2160

caatcaaaac acagctttat tacctcatgc gaactcatac aaaccaatag aatttcaaca     2220

tgttctgtag cttagagtgc tcacttacta cctctgaaca atactcacgc tgtagtttgt     2280

ctctttctta tctttttgca tcttgtaatt aactctttgt ttcccttcat aaaatgtaat     2340

gtacattgta atcttttaaa agaaaaatca gggttgcact tgcaactttt aaaaaaccga     2400

gtgtggaaac attgggtctt aattcaacac aggatcggta aaactgttgt aaatactgag     2460

aaacattttg aatgttcttc atcttattac taatccatgc aaaaaaaaaa aaaaaagcag     2520

cgactaattg tgatgcattc agatttcagt attcagtact gtatatttca ccctgtgtaa     2580

tggggccccc tctcctttct ctctttttgt attgtatgcg attctgaaac tgattgagtc     2640

atgaaaataa tttgtggcgg tgattctaat gtattaaaaa cgtttcgtgt tcctttctaa     2700

ctggattaca ccctggattg aaaaagtctt cctcgtggta gttatatgta gtttcaaaca     2760

tgaataaact ttttgctttc atgattaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaa                                                                 2825


<210>  1820
<211>  2669
<212>  DNA
<213>  homo sapiens

<400>  1820
gcggccgcct ccccctcccc ctccccctct ttcttctcct ccctcgtcgc cgccgccgcc       60

gccgccgcct cagccttcgc ctcagccgcc gcccgctccc gcccgcgcgc ggcgggatgg      120

acgatcaatc caggatgctg cagactctgg ccggggtgaa cctggctggc cactcggtgc      180

aggggggcat ggccctgccg cctcccccgc acggccacga aggggcggac ggcgacggca      240

ggaagcagga catcggcgac atcctccacc agatcatgac catcaccgac cagagcttgg      300

acgaggcgca agcaaagaaa catgccctga actgtcacag aatgaaacca gcgctcttca      360

gcgtcctgtg tgagatcaaa gagaaaacag gcatgtaatg aatttactac acatgtgatg      420

aaccttctcc gagaacagag tagaacacgt cccatttctc caaaagagat tgaaagaatg      480

gtgggcatca tccatcgaaa atttagttcc attcagatgc agctcaaaca aagcacttgt      540

gaagcagtta tgattttaag atcaaggttc cttgatgcca gacggaaaag gcgtaacttc      600

agtaaacagg ccacagaaat cttgaatgaa tatttttact cacacctcag caacccctac      660

cccagtgaag aagccaaaga ggagctggcc aagaaatgca gcatcacagt gtcacaggta      720

tccaattggt ttggcaacaa acgaatcagg tacaagaaga acattggcaa gtttcaggaa      780

gaagccaacc tctatgctgc aaagacggcc gtgacagctg cacacgcagt agcagcagct      840

gtgcagaaca accagaccaa ttcgcccacc acaccaaatt ccggttcttc tggttctttt      900

aacctcccaa attctgggga catgttcatg aacatgcaga gtctgaatgg ggattcttac      960

caagggtccc aagtcggagc caatgtgcaa tcacaggtgg ataccctccg tcatgttatc     1020

aatcagacgg gaggctacag tgatggcctt ggaggaaatt cactgtacag tccacataat     1080

ttaaatgcta atggaggctg gcaggacgca acaactccat cttctgtgac ttctcctaca     1140

gaaggcccag gaagtgtgca ctcggatacc tctaactaat ctctggccac acttttccct     1200

gagctacatg ccttgataag tgcattcaga gcaataggag gaaaaggaaa gcgtttttgt     1260

agcccaccat ctacagcttt actgtaaaac cttgtcttat tcgagaactt ggtaaatctg     1320

ttttttaagg aatcataatc atttgtattt atacttaaaa acacacaatg ttaaaaaaaa     1380

taaagcactt tatccaatta ggccaagatt taacattgtt gacagtcctg tagctatttt     1440

atcataattt attatcaata ttttacatta atggtttcac agttgccaat tacttggcct     1500

taagggtaaa aagtacaata tacactaaac ctcaaccgtt aaagcagatg caaaaattca     1560

cctcacctaa attgaacttc ttgcatattt ccattactga cttggattgt ctttctttca     1620

tatcactaat ggagttggaa taaagagctg tttgcctatc cctgttaatg atggttgtgt     1680

ttaagaatct tcctcgtcac gtttgtgttc agatctctta tgttataatt agatcagaga     1740

ctggtagcat cgtttctctc tctgaaagca ccagtgccca gagtctgctc ggtaataaaa     1800

ttatggatcc agattgttct gagagacgaa gatacttgct gctgatagag gtgaaaacga     1860

gattgatccg tctggggttt tacggtgtgc actgggtgct gcacagactt gtcaaggttt     1920

gctacgtcct ctgggcatct gcaaaaggcc ctgctctctg gagtgttgta tatagtgtag     1980

caaaagagta tttatacatc ccaccaatca aaacacagct ttattacctc atgcgaactc     2040

atacaaacca atagaatttc aacatgttct gtagcttaga gtgctcactt actacctctg     2100

aacaatactc acgctgtagt ttgtctcttt cttatctttt tgcatcttgt aattaactct     2160

ttgtttccct tcataaaatg taatgtacat tgtaatcttt taaaagaaaa atcagggttg     2220

cacttgcaac ttttaaaaaa ccgagtgtgg aaacattggg tcttaattca acacaggatc     2280

ggtaaaactg ttgtaaatac tgagaaacat tttgaatgtt cttcatctta ttactaatcc     2340

atgcaaaaaa aaaaaaaaaa gcagcgacta attgtgatgc attcagattt cagtattcag     2400

tactgtatat ttcaccctgt gtaatggggc cccctctcct ttctctcttt ttgtattgta     2460

tgcgattctg aaactgattg agtcatgaaa ataatttgtg gcggtgattc taatgtatta     2520

aaaacgtttc gtgttccttt ctaactggat tacaccctgg attgaaaaag tcttcctcgt     2580

ggtagttata tgtagtttca aacatgaata aactttttgc tttcatgatt aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                                       2669


<210>  1821
<211>  2556
<212>  DNA
<213>  homo sapiens

<400>  1821
gcggccgcct ccccctcccc ctccccctct ttcttctcct ccctcgtcgc cgccgccgcc       60

gccgccgcct cagccttcgc ctcagccgcc gcccgctccc gcccgcgcgc ggcgggatgg      120

acgatcaatc caggatgctg cagactctgg ccggggtgaa cctggctggc cactcggtgc      180

aggggggcat ggccctgccg cctcccccgc acggccacga aggggcggac ggcgacggca      240

ggaagcagga catcggcgac atcctccacc agatcatgac catcaccgac cagagcttgg      300

acgaggcgca agcaaagaaa catgccctga actgtcacag aatgaaacca gcgctcttca      360

gcgtcctgtg tgagatcaaa gagaaaacag gcatgtaatg aatttactac acatgtgatg      420

aaccttctcc gagaacagag tagaacacgt cccatttctc caaaagagat tgaaagaatg      480

gtgggcatca tccatcgaaa atttagttcc attcagatgc agctcaaaca aagcacttgt      540

gaagcagtta tgattttaag atcaaggttc cttgatgcca gacggaaaag gcgtaacttc      600

agtaaacagg ccacagaaat cttgaatgaa tatttttact cacacctcag caacccctac      660

cccagtgaag aagccaaaga ggagctggcc aagaaatgca gcatcacagt gtcacaggta      720

tccaattggt ttggcaacaa acgaatcagg tacaagaaga acattggcaa gtttcaggaa      780

gaagccaacc tctatgctgc aaagacggcc gtgacagctg cacacgcagt agcagcagct      840

gtgcagaaca accagaccaa ttcgcccacc acaccaaatt ccggtggata ccctccgtca      900

tgttatcaat cagacgggag gctacagtga tggccttgga ggaaattcac tgtacagtcc      960

acataattta aatgctaatg gaggctggca ggacgcaaca actccatctt ctgtgacttc     1020

tcctacagaa ggcccaggaa gtgtgcactc ggatacctct aactaatctc tggccacact     1080

tttccctgag ctacatgcct tgataagtgc attcagagca ataggaggaa aaggaaagcg     1140

tttttgtagc ccaccatcta cagctttact gtaaaacctt gtcttattcg agaacttggt     1200

aaatctgttt tttaaggaat cataatcatt tgtatttata cttaaaaaca cacaatgtta     1260

aaaaaaataa agcactttat ccaattaggc caagatttaa cattgttgac agtcctgtag     1320

ctattttatc ataatttatt atcaatattt tacattaatg gtttcacagt tgccaattac     1380

ttggccttaa gggtaaaaag tacaatatac actaaacctc aaccgttaaa gcagatgcaa     1440

aaattcacct cacctaaatt gaacttcttg catatttcca ttactgactt ggattgtctt     1500

tctttcatat cactaatgga gttggaataa agagctgttt gcctatccct gttaatgatg     1560

gttgtgttta agaatcttcc tcgtcacgtt tgtgttcaga tctcttatgt tataattaga     1620

tcagagactg gtagcatcgt ttctctctct gaaagcacca gtgcccagag tctgctcggt     1680

aataaaatta tggatccaga ttgttctgag agacgaagat acttgctgct gatagaggtg     1740

aaaacgagat tgatccgtct ggggttttac ggtgtgcact gggtgctgca cagacttgtc     1800

aaggtttgct acgtcctctg ggcatctgca aaaggccctg ctctctggag tgttgtatat     1860

agtgtagcaa aagagtattt atacatccca ccaatcaaaa cacagcttta ttacctcatg     1920

cgaactcata caaaccaata gaatttcaac atgttctgta gcttagagtg ctcacttact     1980

acctctgaac aatactcacg ctgtagtttg tctctttctt atctttttgc atcttgtaat     2040

taactctttg tttcccttca taaaatgtaa tgtacattgt aatcttttaa aagaaaaatc     2100

agggttgcac ttgcaacttt taaaaaaccg agtgtggaaa cattgggtct taattcaaca     2160

caggatcggt aaaactgttg taaatactga gaaacatttt gaatgttctt catcttatta     2220

ctaatccatg caaaaaaaaa aaaaaaagca gcgactaatt gtgatgcatt cagatttcag     2280

tattcagtac tgtatatttc accctgtgta atggggcccc ctctcctttc tctctttttg     2340

tattgtatgc gattctgaaa ctgattgagt catgaaaata atttgtggcg gtgattctaa     2400

tgtattaaaa acgtttcgtg ttcctttcta actggattac accctggatt gaaaaagtct     2460

tcctcgtggt agttatatgt agtttcaaac atgaataaac tttttgcttt catgattaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                               2556


<210>  1822
<211>  5231
<212>  DNA
<213>  homo sapiens

<400>  1822
ctatcagtct cgcgctcacc gcccggctga ggaggtgaaa gtttctcccc aggaagataa       60

accgcaaaag acaatattgt gcatgatttg cgccttttct ttggcttttt ctttctttct      120

tcaccccccc acccactttt tttttttttt ttttcaaaaa gcagagaggg aaaaacggag      180

agtgaaggag cgaggaggcg agcgtgagag aaaggagaga gagagaaaag aaagggcgag      240

gggctagtgg agaagtaagg aggggcgcgc tgcgcgaggc ggagagaggg cgaagcagtc      300

gcggcactgg cgctcacatt cctctatgct acaaatccag gaggaagttt ttttttaggg      360

ggctgagatg ctccatgcct ttccccgggc agccttgacg cgcggccctc tcggcagaga      420

ctgagcggcg agaaagtgcg agccgggccg gcagaatctg cctggcgggc gctggagcct      480

gcgttactcg cggcccgcag ccgtccggct actttgcgtt tggcccggcc agcgcccggg      540

cgcgccgcgc cattgcctgc aggctaggac ttcgcgaggt gggtcgactc cccctccctc      600

ctcctcttct tcctcctctt cctcctcctc ttgttcctcc tcctcctccc gattttccct      660

cctcggctgg cgagggtggg gggggcgggg gaggccgggg ctcgccccga gcagccacga      720

tgctcctgga cgccggcccc cagtacccag cgatcggcgt gaccaccttt ggcgcgtccc      780

gccaccactc cgcgggcgac gtggccgaac gagacgtggg cctgggcatc aacccgttcg      840

ccgacggcat gggcgccttc aagctcaacc ccagttcgca cgagctggct tcggccggcc      900

agacggcctt cacgtcgcag gcgccaggct acgcggctgc tgcggccctg ggccatcacc      960

atcacccggg ccacgtcggc tcctattcca gcgcagcctt caactccacg cgggactttc     1020

tgttccgcaa ccggggtttt ggcgacgcgg cggcggcagc cagcgcacag cacagcctct     1080

ttgctgcatc ggccgggggc ttcgggggcc cacacggcca cacggacgcc gcgggccacc     1140

tcctcttccc cgggcttcac gagcaggctg ccggccacgc gtcgcctaac gtggtcaacg     1200

ggcagatgag gctcggcttc tcgggggaca tgtacccgcg accggagcag tacggccagg     1260

tgaccagccc gcgttcggag cactatgctg cgccgcagct gcacggctac gggcccatga     1320

acgtgaacat ggccgcgcat cacggcgccg gcgccttctt ccgctacatg cgccaaccca     1380

tcaagcaaga gctcatctgc aagtggatcg agcccgagca gctggccaac cccaaaaagt     1440

cgtgcaacaa aactttcagc accatgcacg agctagttac gcacgtcacc gtggagcacg     1500

taggtggccc ggagcagagt aatcacatct gcttctggga ggagtgtccg cgcgagggca     1560

agcccttcaa agccaaatac aaactggtta accacatccg cgtgcacacg ggcgagaagc     1620

cctttccctg ccccttccct ggctgtggca aggtcttcgc gcgctccgag aatttaaaga     1680

tccacaaaag gacgcacaca ggggagaagc ccttcaagtg cgagtttgag ggctgtgacc     1740

ggcgcttcgc taacagcagc gaccgcaaga agcacatgca cgtgcacacg agcgacaagc     1800

cctatctttg caagatgtgc gacaagtcct acacgcatcc cagttcgctg cgcaaacaca     1860

tgaaggtcca cgaatcctcc tcgcagggct cgcagccttc gccggccgcc agctctggct     1920

acgaatcctc cacgcctccc accatcgtgt ctccctccac agacaacccg accacaagct     1980

ccttatcgcc ctcctcctcc gcagtccacc acacagccgg ccacagtgcg ctctcttcca     2040

attttaacga atggtacgtt taaaatcaga aacaaaacat cgaacaaaac cctatttaag     2100

agactgatca cacacgtata cacaacatta ctgaaagaac cctgcgaatc aaaacaaccc     2160

ccacacagac cccgcaatcc ttttttaaaa aatctgccaa tagacccagg acgagtaaga     2220

gaggaagcat caacctttta aaaatttcct ttcgctttca ttatttttct ttttttggca     2280

aaggcttggt acccaaggtg cggtaggggg tcgaggggga ggaggccacc tgaccaaatg     2340

ccgccaaccc cgagggccag tttcttgtcg aattggtacg ggctctctgg ggcttcggct     2400

tctttttttc tttgttttct tgtaaataca gaattattag cttaaaactg tactgttgaa     2460

ttctgtaaat agttatatct cggttggagc gggtgggtgg gattgtggcg ttgtggtctt     2520

tgcattgggg gaggggggag ggaccggatg ggcgggggga gggggagggg gaggggtggg     2580

cggccgaaag ccaactgttt gtactgaatg gcaagaatgt tctagtaaat gtgtaccaaa     2640

atgtgaatta ctttgtacga ttacagtctc cacgtcgacc taacccaata ttattggtat     2700

taatgtgctt tttttgtata aagtgcaaac atttcgtccc aaagtctaag tactttagtg     2760

cagtaaaatg ttgtttcatg tcctgtcaag aattcgtata gtacgagcct ggatctgcgt     2820

gtcaaactgt tccatttgtt tatgtaaagt gatattaaaa aagatataaa ctataactgt     2880

ccgttacttt tggcaaaaga tacaaccaca taatgtatat aattcctagt ttccatattt     2940

atccgcatgt aaagggccgg tttatccatg ttacagctct tcaatattta tggctagaag     3000

aactcgtatg tacactttag tttccagaac tgtttggtaa cctttcgtac cttattaaag     3060

attcttaaat ctccgtgatt gtggtaggaa tttcttcttc acccaccagc aacctgctgc     3120

ctcttctgcc agtcttaaag ggtctccaga aaagctctcc agtctccctt gccttccctt     3180

tctgtcactg caggtcgtat aaacgtgata aatgaatgct accctgctgg ctctccgaga     3240

gagtgtaatt agtatttata tcaaaattta tgaaacaaat tttcggccgc agtataattt     3300

aaatgacctt tgcagatgta gaataacaac cataaaaata acaggaatag attgcacagg     3360

cgacatcaat attaatgtag acgaattgtc agaagctcag gggctcgctc tgcaacattg     3420

caaatgaact tgcagccgag ggttccgctg ccccctagat taaattcccc gggctgaaac     3480

tgagttgcag atttacaata tcatatttta aattgctgtc ttcaattaaa ccatttatga     3540

ccataactaa ttttcaggat gtcgatgcat gcttttccag gccttccttc tttgtacaaa     3600

agtaaatgtc cataaagcgt ttcacttata ttcttcaaac atgatgctaa tttaaattaa     3660

ttacttccta tgatatgtta ttattcctat gattttgcca ctgttattag ttctctcaaa     3720

aatacatcta gggaagagga ttattttaag taatttgatt atctttctat ctcttttatt     3780

tatttctcat ttacttaaga aattcgttcc attggttggc attgatacag taaatttgta     3840

aatgaggaga caatataaaa aatctaaatt acttgtgctt aatgactgta gcagaatgcc     3900

ttttctctaa atcagattgt ctttcttgca gtttagtttg atagatttgc aagctatgct     3960

gcttccatga agttagctgc gctggtagga acgcaggctt ctttgtctct ggttgtagct     4020

tgcatgatcg ccccattagg cagacaacgt agccggagat cacaaatcag gcccttggct     4080

gtagttgcta gtgtgtggag gtgcagagca ggtggcagaa actgacctca ctgggcaagg     4140

gtggccatgg acctgattct ttaatgcact ctatgtgttc aggaagccac aggccatatt     4200

tgactctgag aaagaaaaca agaggaaaaa ccccacaaag tataacaacc ccttaagata     4260

catctatttt aaagtgaaat taatttttca gtttatacca ttggccaatt acaagataaa     4320

aatgttcaat ttctttaaga atcctttgtt gacttgtctt ttcatctctt gctatttata     4380

tttgtcactg tttcaacaaa gtcttatttg ctgaggaagg actttgctgc acttactgta     4440

ccacatcaaa cactggggag ggtggtgttt aactttttaa aaaatgttat tctgattata     4500

acaataatat tggctttttt catgaaaaga gcgccacctt gcaaggttta gtgagattta     4560

tggaagttga atacctaagc aggaattgct gctagctcca aaaatttgcg aagcaaaagc     4620

tagccccaat tggtttggaa gtttgaaact gattaacaga tttgcatttg aagtgactcc     4680

agacattagg tccagacatt agttaaaaat agaaagagga ataaagacat ctcttctctc     4740

tagaaaagat aacaccacaa ttaataatcc ttcccacttt cattgagatc agcttgtctg     4800

ataacctgat atgagtgtga taatgataaa catgataata gtggtacttt tgtaattttg     4860

ctggtgcatt taagaagata gtaaatgatg agttcatctt ttcttcgaac attcctattc     4920

ctagatgtag tttacctcaa attgggaatt ataactgtct aatttttgtt gtgtacctga     4980

tgcccctttt gctttaatac cacagtgtaa caattaaata tcacactatg acatatgatt     5040

taagtaggat attttaaaga taaattttag gggtaaatgt ttacttcaaa atgactccat     5100

atttcaaata tctgtttaga ctgtgaaggc caaataattt ttaagaaaac atttgaagag     5160

tagtgtgttt gcatttgtga ataatcttac tcacagcaag taaacgtaat aaaagccaac     5220

atttaagcca a                                                          5231


<210>  1823
<211>  2991
<212>  DNA
<213>  homo sapiens

<400>  1823
ccgcctggct ttggactctt ctcctcctcc acctcctcct cctcctcccg cgccgccgcc       60

tcctcctcct cttcctctcc gcgccttcgc tacgcgcccg gccgcccgag gcagatccag      120

gcggcggcgg aggcggcggg cgcaggagag cggctcccag ggctgaagtg gccgccacca      180

ccgccgcctg cgcctggagc ccggtggccg ccggacgcac cgcgcggatc gggagcggga      240

gtcgaggcgg cgcggaggcg cagggctcgc aggggcgggc gggcgcgctg gccatgctcc      300

tggacgcggg tccgcagttc ccggccatcg gggtgggcag cttcgcgcgc caccatcacc      360

actccgccgc ggcggcggcg gcggctgccg ccgagatgca ggaccgtgaa ctgagcctgg      420

cggcggcgca gaacggcttc gttgactccg ccgccgcgca catgggagcc ttcaagctca      480

acccgggcgc gcacgagctg tccccgggcc agagctcggc gttcacgtcg cagggccccg      540

gcgcctaccc cggctccgct gcggctgccg ctgcggccgc agcgctcggg ccccacgccg      600

cgcacgttgg ctcctactct gggccgccct tcaactccac ccgggacttc ctgttccgca      660

gccgcggctt cggggactcg gcgccgggcg gcgggcagca cgggctgttc gggccgggcg      720

cgggcggcct gcaccacgcg cactcggacg cgcagggcca cctcctcttc ccgggcctgc      780

cagagcagca cgggccgcac ggctcgcaga atgtgctcaa cgggcagatg cgcctcgggc      840

tgcccggcga ggtgttcggg cgctcggagc aataccgcca ggtggccagc ccgcggaccg      900

acccctactc ggcggcgcaa ctccacaacc agtacggccc catgaatatg aacatgggta      960

tgaacatggc agcagccgcg gcccaccacc accaccacca ccaccaccac cccggtgcct     1020

ttttccgcta tatgcggcag cagtgcatca agcaggagct aatctgcaag tggatcgacc     1080

ccgagcaact gagcaatccc aagaagagct gcaacaaaac tttcagcacc atgcacgagc     1140

tggtgacaca cgtctcggtg gagcacgtcg gcggcccgga gcagagcaac cacgtctgct     1200

tctgggagga gtgtccgcgc gagggcaagc ccttcaaggc caaatacaaa ctggtcaacc     1260

acatccgcgt gcacacaggc gagaaaccct tcccctgccc cttcccgggc tgtggcaaag     1320

tcttcgcgcg ctccgagaac ctcaagatcc acaaaaggac ccacacaggg gagaagccgt     1380

tccagtgtga gtttgagggc tgcgaccggc gcttcgccaa cagcagcgac aggaagaagc     1440

acatgcacgt ccacacctcc gataagccct atctctgcaa gatgtgcgac aagtcctaca     1500

cgcaccccag ctcgctgcgg aagcacatga aggtccatga gtcctccccg cagggctctg     1560

aatcctcccc ggccgccagc tccggctatg agtcgtccac gcccccgggg ctggtgtccc     1620

ccagcgccga gccccagagc agctccaacc tgtccccagc ggcggcggca gcggcggcgg     1680

cggctgcggc ggcggcggcc gcggtgtccg cggtgcaccg gggcggaggc tcgggcagtg     1740

gcggcgcggg aggcggctca ggcggcggca gcggcagtgg cgggggcggc ggcggggcgg     1800

gcggcggggg cggcggcagc tctggcgggg gcagcgggac agccgggggt cacagcggcc     1860

tctcctccaa cttcaatgaa tggtacgtgt gacgggtcgg ggcctctctc cctctccctg     1920

tccccacccc agcgcagcag ccctccccgc agctagcagc gagggcacct tgtgatcatg     1980

ttgttaaaat tatgaatctg atttttatga tgatgaaaat tttaccagca gaaggatttt     2040

ttaaagtttt tttttttttt ttaataataa tctaggcatg aagagcaaaa atatcccttc     2100

cggagtcttt gaagctgaaa atataaaaca aataaaaaat aaaaaaataa aaacccacaa     2160

aaatgttgaa ccaaacctcc ctgctaatct ccatgcccac gttctttccc accctgttcc     2220

cagtcttctg acaaactgtg tacatagcgg actcctcctt tctcctccga ggtggtttta     2280

aaggcttttt ggtgtataga agtttgtcca tttgtaaaac tccggattgc gttcctcccc     2340

gccttccgcc ccttcccttc cctaaagtga tgggctttct cttttctctt tttagtttac     2400

ccggtttctt tttaagtaat gtggaagaaa atggtttatt ttgtattgtg gtattgaata     2460

ttgtgttcct ttttatgagg caacctgatt gtaaacttca tgtaactata gactggaaaa     2520

aatgagccgt gccaaagtct cccttctgtt tcttcagcac attgacccat agcacacaca     2580

tacacaccac caccaacaac gcttgtgaat gtatttttct gttagctggg tttacatgtg     2640

atgttttagt gcttttgcaa gttcaatttg ttagttcctg tatgaaagat tgtgggggaa     2700

aaataaacgt cgtgccgtta gctttttccg taataacacc cttccttctg taaatacccg     2760

ttaccatatt tatccatttg taattaaatt atggtattaa cttgctacag aggaaacaat     2820

atttataaag aatgtttctt aactataaat atgtacaatt gtgggcataa actgtttcag     2880

attttttatt tgaaggtttt aagtggtttg atcatttctt gtgatgtttt gagagtaatg     2940

catacagaaa tataataaaa tgtgttgaaa ctgcaaaaaa aaaaaaaaaa a              2991


<210>  1824
<211>  4687
<212>  DNA
<213>  homo sapiens

<400>  1824
agcctcctcc actccctcct cctcctcctc ctcgcacggt aatgggaggc tcctaggcag       60

gagaagcaaa agaaggaatt gtttgcgagt tcagtcatcc aaaaagcttc ttccatatgg      120

agggaccggg tgcgctgggc gcggcgtccc ctgcgttgtc ctcctgctgc cgcccccgcg      180

gccgccgctt tctgccgcgg ggaccctgag ccccggcccg ccggtgtcag ccgccgcgcg      240

cgcgcacaga cacacacaca gagacacaca aacacacaca gaaaagacac acacgcgcac      300

acacggcgcg cacaccctca cgcccgccac agccacaaca cgcccgcacg cgccctccct      360

ctccggcccg caacttctcg gtcctcggct cctttgttgc tccagccgcg gccgctcgcc      420

cgtgttgtgt gtccccggtg tcaccgagcg tgttgtgtgt ccgtgcggcg cggcgctgtg      480

tggctccctc gcgcccacca cgctggcccc cgggccccgg ctcgcccttc ccaggcgccg      540

gctgcagcag agtttcagaa caagcttcct ggaacccatg acccatgaag tcttgtcgac      600

atttataccg tctgagggta gcagctcgaa agtagaagaa agtgttgcca gggacggcag      660

tatctctttg tgtgaccctg gcggcttatg ggacgttggc ttcagacctt tgtgatacac      720

catgctgcgt gggacgatga cggcgtggag aggaatgagg cctgaggtca cactggcttg      780

cctcctccta gccacagcag gctgctttgc tgacttgaac gaggtccctc aggtcaccgt      840

ccagcctgcg tccaccgtcc agaagcccgg aggcactgtg atcttgggct gcgtggtgga      900

acctccaagg atgaatgtaa cctggcgcct gaatggaaag gagctgaatg gctcggatga      960

tgctctgggt gtcctcatca cccacgggac cctcgtcatc actgccctta acaaccacac     1020

tgtgggacgg taccagtgtg tggcccggat gcctgcgggg gctgtggcca gcgtgccagc     1080

cactgtgaca ctagccaatc tccaggactt caagttagat gtgcagcacg tgattgaagt     1140

ggatgaggga aacacagcag tcattgcctg ccacctgcct gagagccacc ccaaagccca     1200

ggtccggtac agcgtcaaac aagagtggct ggaggcctcc agaggtaact acctgatcat     1260

gccctcaggg aacctccaga ttgtgaatgc cagccaggag gacgagggca tgtacaagtg     1320

tgcagcctac aacccagtga cccaggaagt gaaaacctcc ggctccagcg acaggctacg     1380

tgtgcgccgc tccaccgctg aggctgcccg catcatctac cccccagagg cccaaaccat     1440

catcgtcacc aaaggccaga gtctcattct ggagtgtgtg gccagtggaa tcccaccccc     1500

acgggtcacc tgggccaagg atgggtccag tgtcaccggc tacaacaaga cgcgcttcct     1560

gctgagcaac ctcctcatcg acaccaccag cgaggaggac tcaggcacct accgctgcat     1620

ggccgacaat ggggttgggc agcccggggc agcggtcatc ctctacaatg tccaggtgtt     1680

tgaaccccct gaggtcacca tggagctatc ccagctggtc atcccctggg gccagagtgc     1740

caagcttacc tgtgaggtgc gtgggaaccc cccgccctcc gtgctgtggc tgaggaatgc     1800

tgtgcccctc atctccagcc agcgcctccg gctctcccgc agggccctgc gcgtgctcag     1860

catggggcct gaggacgaag gcgtctacca gtgcatggcc gagaacgagg ttgggagcgc     1920

ccatgccgta gtccagctgc ggacctccag gccaagcata accccaaggc tatggcagga     1980

tgctgagctg gctactggca cacctcctgt atcaccctcc aaactcggca accctgagca     2040

gatgctgagg gggcaaccgg cgctccccag acccccaacg tcagtggggc ctgcttcccc     2100

gcagtgtcca ggagagaagg ggcagggggc tcccgccgag gctcccatca tcctcagctc     2160

gccccgcacc tccaagacag actcatatga actggtgtgg cggcctcggc atgagggcag     2220

tggccgggcg ccaatcctct actatgtggt gaaacaccgc aaggtcacaa attcctctga     2280

cgattggacc atctctggca ttccagccaa ccagcaccgc ctgaccctca ccagacttga     2340

ccccgggagc ttgtatgaag tggagatggc agcttacaac tgtgcgggag agggccagac     2400

agccatggtc accttccgaa ctggacggcg gcccaaaccc gagatcatgg ccagcaaaga     2460

gcagcagatc cagagagacg accctggagc cagtccccag agcagcagcc agccagacca     2520

cggccgcctc tcccccccag aagctcccga caggcccacc atctccacgg cctccgagac     2580

ctcagtgtac gtgacctgga ttccccgtgg gaatggtggg ttcccaatcc agtccttccg     2640

tgtggagtac aagaagctaa agaaagtggg agactggatt ctggccacca gcgccatccc     2700

cccatcgcgg ctgtccgtgg agatcacggg cctagagaaa ggcacctcct acaagtttcg     2760

agtccgggct ctgaacatgc tgggggagag cgagcccagc gccccctctc ggccctacgt     2820

ggtgtcgggc tacagcggtc gcgtgtacga gaggcccgtg gcaggtcctt atatcacctt     2880

cacggatgcg gtcaatgaga ccaccatcat gctcaagtgg atgtacatcc cagcaagtaa     2940

caacaacacc ccaatccatg gcttttatat ctattatcga cccacagaca gtgacaatga     3000

tagtgactac aagaaggata tggtggaagg ggacaagtac tggcactcca tcagccacct     3060

gcagccagag acctcctacg acattaagat gcagtgcttc aatgaaggag gggagagcga     3120

gttcagcaac gtgatgatct gtgagaccaa agctcggaag tcttctggcc agcctggtcg     3180

actgccaccc ccaactctgg ccccaccaca gccgcccctt cctgaaacca tagagcggcc     3240

ggtgggcact ggggccatgg tggctcgctc cagcgacctg ccctatctga ttgtcggggt     3300

cgtcctgggc tccatcgttc tcatcatcgt caccttcatc cccttctgct tgtggagggc     3360

ctggtctaag caaaaacata caacagacct gggttttcct cgaagtgccc ttccaccctc     3420

ctgcccgtat actatggtgc cattgggagg actcccaggc caccaggcca gtggacagcc     3480

ctacctcagt ggcatcagtg gacgggcctg tgctaatggg atccacatga ataggggctg     3540

cccctcggct gcagtgggct acccgggcat gaagccccag cagcactgcc caggcgagct     3600

tcagcagcag agtgacacca gcagcctgct gaggcagacc catcttggca atggatatga     3660

cccccaaagt caccagatca cgaggggtcc caagtctagc ccggacgagg gctctttctt     3720

atacacactg cccgacgact ccactcacca gctgctgcag ccccatcacg actgctgcca     3780

acgccaggag cagcctgctg ctgtgggcca gtcaggggtg aggagagccc ccgacagtcc     3840

tgtcctggaa gcagtgtggg accctccatt tcactcaggg cccccatgct gcttgggcct     3900

tgtgccagtt gaagaggtgg acagtcctga ctcctgccaa gtgagtggag gagactggtg     3960

tccccagcac cccgtagggg cctacgtagg acaggaacct ggaatgcagc tctccccggg     4020

gccactggtg cgtgtgtctt ttgaaacacc acctctcaca atttaggcag aagctgatat     4080

cccagaaaga ctatatattg tttttttttt aaaaaaaaaa agaagaaaaa agagacagag     4140

aaaattggta tttatttttc tattatagcc atatttatat atttatgcac ttgtaaataa     4200

atgtatatgt tttataattc tggagagaca taaggagtcc tacccgttga ggttggagag     4260

ggaaaataaa gaagctgcca cctaacagga gtcacccagg aaagcaccgc acaggctggc     4320

gcgggacaga ctcctaacct ggggcctctg cagtggcagg cgaggctgca ggaggcccac     4380

agataagctg gcaagaggaa ggatcccagg cacatggttc atcacgagca tgagggaaca     4440

gcaaggggca cggtatcaca gcctggagac acccacacag atggctggat ccggtgctac     4500

gggaaacatt ttcctaagat gcccatgaga acagaccaag atgtgtacag cactatgagc     4560

attaaaaaac cttccagaat caataatccg tggcaacata tctctgtaaa aacaaacact     4620

gtaacttcta aataaatgtt tagtcttccc tgtaaccttc aaactgaaaa aaaaaaaaaa     4680

aaaaaaa                                                               4687


<210>  1825
<211>  2548
<212>  DNA
<213>  homo sapiens

<400>  1825
attccacagc ggccgcaacg tgtcgagagc cgtaagtaaa gtgtcgcaaa gcagaaggaa       60

ggcgggagtc ccgactgcaa acattgagga aagccaggca gtagaggccg ctatggcgaa      120

cgttccgtgg gcagaggtct gcgagaaatt ccaggcggcg ctcgctctgt cgcgggtgga      180

actgcataaa aatccggaga aggaaccata caagtccaaa tacagcgccc gggcgctact      240

ggaagaggtc aaggcgctgc tcggccctgc gcctgaggac gaggatgagc ggcctgaggc      300

cgaggacggc ccgggtgccg gtgaccacgc cctggggctg ccggctgagg tggtggagcc      360

cgaggggccc gtcgcccagc gagcggtgag gctggcagtc atcgagttcc acctcggggt      420

gaaccacatc gacacggagg agctgtcggc gggggaggag cacctggtga aatgcctgcg      480

gctgctgcgc aggtaccggc tctcgcacga ctgcatctct ctctgcatcc aggcgcagaa      540

taacctgggt atcttgtggt ctgaaagaga agaaattgaa actgcacagg cttacctaga      600

gtcatcagaa gcactatata atcagtatat gaaagaggtt gggagtcctc ctcttgatcc      660

tactgagcgt tttcttcctg aagaagagaa acttactgaa caagagagat caaaaagatt      720

tgaaaaggtt tatactcata acctatatta cctagctcaa gtctaccagc atctggaaat      780

gtttgagaag gctgctcact attgccatag tacactaaaa cgccagcttg agcacaatgc      840

ctaccatcct atagagtggg ctatcaatgc tgctaccttg tcacagtttt acatcaataa      900

gctatgcttt atggaggcca ggcactgttt atcagctgct aatgtcattt ttggtcaaac      960

tggaaagatc tcagccacag aagacactcc tgaagctgaa ggagaagtgc cagagcttta     1020

tcatcaaaga aagggggaaa tagcaaggtg ctggatcaaa tactgtttga ctctcatgca     1080

gaatgcccaa ctctccatgc aggacaacat aggagagctt gatcttgata aacagtctga     1140

acttagagct ttaaggaaaa aagaactaga tgaggaggaa agcattcgga aaaaagctgt     1200

gcagtttgga accggtgaac tgtgtgatgc catctctgca gtagaagaga aagtgagcta     1260

cttgagacct ttagattttg aagaagccag agaacttttc ttattgggtc agcactatgt     1320

ctttgaggca aaagagttct ttcagattga tggttatgtc actgaccata ttgaagttgt     1380

ccaagaccac agtgctctgt ttaaggtgct tgcattcttt gaaactgaca tggagagacg     1440

gtgcaagatg cataaacgca gaatagccat gctagagccc ctaactgtag acctgaatcc     1500

acagtattat ctgttggtca acagacagat ccagtttgaa attgcacatg cttactatga     1560

tatgatggat ttgaaggttg ccattgctga caggctaagg gatcctgatt cacacattgt     1620

aaaaaaaata aataatctta ataagtcagc actgaagtac taccagctct tcttagactc     1680

cctgagagac ccaaataaag tattccctga gcatataggg gaagatgttc ttcgccctgc     1740

catgttagct aagtttcgag ttgcccgtct ctatggcaaa atcattactg cagatcccaa     1800

gaaagagctg gaaaatttgg caacatcatt ggaacattac aaatttattg ttgattactg     1860

tgaaaagcat cctgaggccg cccaggaaat agaagttgag ctagaactta gtaaagagat     1920

ggttagtctt ctcccaacaa aaatggagag attcagaacc aagatggccc tgacttaatc     1980

cttgttttta aagaaaggaa atgtgcaata ttgaagtgat ctttttccct agtcagacag     2040

gcccaattcc attgtgatgt ttacctttat agccaggtga gtgcagtttg aacttgagat     2100

acagtcaact gagtgtttgc taggatccta aggaacataa agttaattaa aaacttacac     2160

ctaattatgt aaattgcctt gttaaagaca tgtgatttgt attttagatg cttgtttcct     2220

attaaaatac agacatttct accctcagtt tctaaatgta gactatttgt tggctagtac     2280

ttgatagatt ccttgtaaga aaaaatgctg ggtaatgtac ctggtaacaa gcctgttaat     2340

atattaagat tgaaaaagta acttctatag ttactccttc taaaatattt gacttcctaa     2400

attcccccca cccaaaatct ttcccttttg aaaatactaa aaactaagtt atgttattat     2460

aaagtgtaaa atggtttgtc ttaattatag gagaaaaagg ccttgttaga aataaaataa     2520

actgacttat ttcactaatg aaaacaaa                                        2548


<210>  1826
<211>  4111
<212>  DNA
<213>  homo sapiens

<400>  1826
gatgagcatg tgttgaatcc tcaagagagg agggaggaag caagaaggaa agcttgaagg       60

gaggagggga ggggggcagg tgctgatttc agccctgtag cgtcaggatt gcgtcaattc      120

gggttccagc cacgtctgga gtctcggaga cgagcttctc agaagagcca aaacaggaac      180

cgaggtggca aatcactgtg cgagggcgag tggacctccc tctttgcctc ctccctgttc      240

caggagctgg tgccctgggc tctgcgctgt tgttttcagc gctccgaaag ccggcgcttg      300

agatccaggc aagtgaatcc agccaggcag ttttcccttc agcacctcgg acagaacacg      360

cagtaaaaaa tggctccgat caccaccagc cgggaagaat ttgatgaaat ccccacagtg      420

gtggggatct tcagtgcatt tggcctggtc ttcacagtct ctctctttgc atggatctgc      480

tgtcagagaa aatcatccaa gtctaacaag actcctccat acaagtttgt gcatgtgctt      540

aagggagttg atatttaccc tgaaaaccta aatagcaaaa agaagtttgg agcagatgat      600

aaaaatgaag taaagaataa gccagctgtg ccaaagaatt cattgcatct ggatcttgaa      660

aagagagatc tcaatggcaa ttttcccaaa accaacctca aacctggcag tccttctgat      720

ctggagaatg caaccccgaa gctcttttta gaaggggaaa aagagtcagt ttcccctgag      780

agtttaaagt ccagcacttc ccttacttca gaagagaaac aagagaagct gggaactctc      840

ttcttctcct tagaatacaa cttcgagaga aaagcatttg tggtcaatat caaggaagcc      900

cgtggcttgc cagccatgga tgagcagtcg atgacctctg acccatatat caaaatgacg      960

atcctcccag agaagaagca taaagtgaaa actagagtgc tgagaaaaac cttggatcca     1020

gcttttgatg agacctttac attctatggg ataccctaca cccaaatcca agaattggcc     1080

ttgcacttca caattttgag ttttgacagg ttttcaagag atgatatcat tggggaagtt     1140

ctaattcctc tctcgggaat tgaattatct gaaggaaaaa tgttaatgaa tagagagatc     1200

atcaagagaa atgttaggaa gtcttcagga cggggtgagt tactgatctc tctctgctat     1260

cagtccacca caaacactct aactgtggtt gtcttaaaag ctcgacatct gcctaaatct     1320

gatgtgtccg gactttcaga tccctatgtc aaagtgaacc tgtaccatgc caaaaagaga     1380

atctccaaga agaagactca tgtgaagaaa tgcaccccca atgcagtgtt caatgagctg     1440

tttgtctttg atattccttg tgagggcctt gaagatataa gtgttgaatt tttggttttg     1500

gattctgaaa gggggtcccg aaatgaggta atcgggcagt tagtcttggg tgcagcagca     1560

gaaggaactg gtggagagca ctggaaagag atctgtgact accccaggag acaaattgcc     1620

aagtggcacg tgctctgtga tggttagcat cctagccgtg agttggaact taaaggtttt     1680

tactaggcaa ggagaaattt tctttctttc tatattggat tgcaagcttg ggaaatcaag     1740

ctaccttttt gttgttgttg ttgttgctag aaatggattg aattagtaga ccagaaagta     1800

acttcaaatg tgtattatga taatttccct atttattaga agagttggat aaattttcat     1860

aagatattca atatctcctt cagattacca gtgatataac taggaatagt cagacatttt     1920

atgaatactg tgccagaatc ccaaattata aatgtgacaa tctcattgga acatgtcaca     1980

aaaagttaat gtgattaaga tttaaaaacg aaaagtatgc cttgccttgt gaaaatttat     2040

ccatttatct tcaggttggg gaaatcaatt tttctttaaa tccaaagata ctaaaaaaat     2100

gtcctccagt ttgtatttat taattctgtc atgtgcaaat ggttgtcctg catataaaag     2160

tatctggtca tttcagtttg gtttgtaatt atttgatgca attttatcat aagagtaact     2220

cagattcatt tcaaaaggac agtgaacaag ctgagaaatt attttatcaa agggctgagt     2280

tgagaacact gtggctgaaa tataattttt ctccccccta aggttacatg tgagtcaaaa     2340

ttttgtaaaa tataacctca cataagaacc atggccttgg attattcact gcctgtcaca     2400

agcctcagtg tggcctgaga aatccctatg tacctttgtg aaattgttga attagttagt     2460

gaataaagaa ataaacttca actagaaatc cagttagaag tgcaattttc ttataggaaa     2520

taggtatagt gtgcaagtgt acttttaagg ccatcgtttg tacccagagt cggcatggcc     2580

acctaagtct tcatttaatt tattgtcccc cagaaaagat taagatgcta cttgaaaaga     2640

ctgtgaagat tttttacatt gccagataaa aagtgttact taaccaacaa acaaatgtaa     2700

gactacaaaa tcgttcaaga gcaattctaa tataatttac atatgttcac gcaaaatatg     2760

cttaggctgt caaattagca caacaaagaa tgtgtttcac tatcttttct aggctaattt     2820

gtcttgagct gttgtctata gagcagttta cagacttgtg tcttgtatca ttttccagtg     2880

ccagggttct gaaattcatt cagaacctgt tagattaaag ctgcaccctg tgattatttg     2940

aaaagaatta gcttgagagt aatgtcacta tatttgagtt cttagagaag tatgagtgga     3000

acttgagtac agttgaatta ttaaatatgc aagttagaaa ttaagtctac tgaaaaattt     3060

acattttgag tcaggttttg tgtcagtact ttagcagttt ttgagaatgt gtttgatatc     3120

acagtgtttg taaattctat gaaaaatgca ttttccaaac aacttataca tgctttttat     3180

gactatgcct aatgtaaaga aaatgtatta cattctgtat gtacaaagat taaaaatcaa     3240

cctctttttt gtgctttaaa atgactttgg gattaaaaaa gcatatttcc caatcattgt     3300

cttcattcca ctacaaagtc acctcacagc atcttgctcc actcggcatc tctgtgaaag     3360

caacatgaaa tgaactgtag taggtgtgta gtttggggaa gtcaaatggc cattttatgt     3420

atgtgcattt ggtatcatgg gccgtggaac agaatatatg ttggacctct gaaaagttgt     3480

aaggggccaa ttctaagtat tcttcacggc agccagaagt taatggtggt agcagctgag     3540

gtatggttgt tggacgaggc cgattttttt ttttttaaca tggaacaatg aaaccaacaa     3600

caaacatttt taaaattaaa atggataatt tgtaaatagt ttttagcttt taaaatttaa     3660

agtgtttttg agtgtgaaaa gttgagtaaa actatttgca actggttttc agaaaagaga     3720

aaagaaacaa caaaggaatt gaaacaggca gggagatctt aatacctaat ttcatcattt     3780

ctgaaaatgt actgttttag aatgtattac aatatcaatg tgaatatctt gaatcctgtt     3840

acaaatcctg cactgtatta aacatgtaaa ttaattgttt gtctgattag ccaatctcac     3900

cacccaaatg gggaggtata catgtttgaa gaactgtgta actcagtaat tgatttgttc     3960

tgatgttgta actcaataga agtgttttgg aaggaagcat ggtgtgtgag acagtgtctg     4020

ttcttttgtg ccagctctgt atgatgtttg taagaccatg tttgtaagac atgaataaat     4080

tgctgctttt gcccaaaaaa aaaaaaaaaa a                                    4111


<210>  1827
<211>  1622
<212>  DNA
<213>  homo sapiens

<400>  1827
gctttctttg tgtggctgaa gcgctagaaa tggcatattt tctttccctt cgttaaaaaa       60

tcagaccctc tttcccctct ctccccgcgg gaacacagct agggagtggg taggagcagg      120

atctgccgac gagggcagag gcggaaaatc ctcgggcgat gagctgaaga gggccgggtc      180

cgggagggat gctgggagct tgactcactc gcacaccatg tgtccctccg cgcgcagcac      240

gggggacttt tcggtgggga ttttgggcgc cgaccagacg cggcattttc ggaaaatagc      300

gccctgtgca gctgaagcgc tttgtgtgta gcggggccgc gtcagcccgg ccgggtacga      360

ggcgcctcgg gtccccgcac cacctcctgc tgccttcccg tcgccgctcc cgaagctttt      420

ccagatgtcc ctggtagatt tgggaaagaa gcttttagaa gcggcacgag caggtcaaga      480

tgatgaagtt cgtattttga tggcaaatgg agctcccttt actacagact ggctgggaac      540

ttctccactt catctagcag cacagtatgg tcattattcc accacagagg tactgctgcg      600

agctggtgtg agcagagatg ccagaaccaa agtggaccga acaccattac atatggcagc      660

ttctgagggc catgccagca tagtagaggt tttacttaag catggtgctg atgtcaatgc      720

aaaggacatg ttaaagatga cagctctcca ttgggccaca gaacacaatc atcaagaggt      780

ggtggaactt ttaatcaaat atggtgctga tgtacacacg caaagtaaat tttgtaaaac      840

tgcatttgat atttcaatag acaatggaaa tgaagattta gcagagatat tacagattgc      900

tatgcagaac caaatcaaca caaacccaga gagtcctgac actgtgacaa tacatgctgc      960

aacaccacag tttatcattg gacctggagg ggtggtgaac ctaacagatg aaacgggtgt     1020

atctgctgtt cagtttggaa actcttctac atcagtatta gctacattag ctgccttagc     1080

tgaagcatct gctccattgt ccaattcttc agaaactcca gtagtggcca cagaagaagt     1140

agttactgca gaatctgtgg atggtgccat tcagcaagta gttagttcag ggggtcagca     1200

agtcatcaca atagttacag atggaattca gcttggaaat ttgcactcta ttccaaccag     1260

tggaattggt cagcccatca ttgtgaccat gccagatgga caacaagtat taacagtacc     1320

agcaacagac attgctgaag aaactgttat aagtgaagaa ccaccagcta agagacaatg     1380

tatcgaaata attgaaaacc gggtggaatc tgcagaaata gaagtaagga gtcttttacc     1440

cggtgtgctt tgccgcagtc atccaaaata aattcaattt tttttgtctt ttatatttat     1500

tactgacagt attgttttga tacagaatga aagtgcgtag tattttcatt ttgtttattt     1560

ttgccttata catatagcaa gccctcaata aataaatatt gaatgaatga aaaaaaaaaa     1620

aa                                                                    1622


<210>  1828
<211>  1658
<212>  DNA
<213>  homo sapiens

<400>  1828
gctttctttg tgtggctgaa gcgctagaaa tggcatattt tctttccctt cgttaaaaaa       60

tcagaccctc tttcccctct ctccccgcgg gaacacagct agggagtggg taggagcagg      120

atctgccgac gagggcagag gcggaaaatc ctcgggcgat gagctgaaga gggccgggtc      180

cgggagggat gctgggagct tgactcactc gcacaccatg tgtccctccg cgcgcagcac      240

gggggacttt tcggtgggga ttttgggcgc cgaccagacg cggcattttc ggaaaatagc      300

gccctgtgca gctgaagcgc tttgtgtgta gcggggccgc gtcagcccgg ccgggtacga      360

ggcgcctcgg gtccccgcac cacctcctgc tgccttcccg tcgccgctcc cgaagctttt      420

ccagatgtcc ctggtagatt tgggaaagaa gcttttagaa gcggcacgag caggtcaaga      480

tgatgaagtt cgtattttga tggcaaatgg agctcccttt actacagact ggctgggaac      540

ttctccactt catctagcag cacagtatgg tcattattcc accacagagg tactgctgcg      600

agctggtgtg agcagagatg ccagaaccaa agtggaccga acaccattac atatggcagc      660

ttctgagggc catgccagca tagtagaggt tttacttaag catggtgctg atgtcaatgc      720

aaaggacatg ttaaagatga cagctctcca ttgggccaca gaacacaatc atcaagaggt      780

ggtggaactt ttaatcaaat atggtgctga tgtacacacg caaagtaaat tttgtaaaac      840

tgcatttgat atttcaatag acaatggaaa tgaagattta gcagagatat tacagattgc      900

tatgcagaac caaatcaaca caaacccaga gagtcctgac actgtgacaa tacatgctgc      960

aacaccacag tttatcattg gacctggagg ggtggtgaac ctaacaggtc tggtatcttc     1020

agaaaattca tccaaggcaa cagatgaaac gggtgtatct gctgttcagt ttggaaactc     1080

ttctacatca gtattagcta cattagctgc cttagctgaa gcatctgctc cattgtccaa     1140

ttcttcagaa actccagtag tggccacaga agaagtagtt actgcagaat ctgtggatgg     1200

tgccattcag caagtagtta gttcaggggg tcagcaagtc atcacaatag ttacagatgg     1260

aattcagctt ggaaatttgc actctattcc aaccagtgga attggtcagc ccatcattgt     1320

gaccatgcca gatggacaac aagtattaac agtaccagca acagacattg ctgaagaaac     1380

tgttataagt gaagaaccac cagctaagag acaatgtatc gaaataattg aaaaccgggt     1440

ggaatctgca gaaatagaag taaggagtct tttacccggt gtgctttgcc gcagtcatcc     1500

aaaataaatt caattttttt tgtcttttat atttattact gacagtattg ttttgataca     1560

gaatgaaagt gcgtagtatt ttcattttgt ttatttttgc cttatacata tagcaagccc     1620

tcaataaata aatattgaat gaatgaaaaa aaaaaaaa                             1658


<210>  1829
<211>  7753
<212>  DNA
<213>  homo sapiens

<400>  1829
cgcgtccatt tgaacgtctc gcacgccttc ctgccattag cactcgagcc cgctgctgtt       60

gcccgttctt cctccagaat aggggaggga gagggaatga gaagctgctg cggcccaaga      120

gtcactgtga aggaccccgc cgctgccctc gggcctcctc ggcccctgcg cctccgggga      180

gcagccgggg ctcgccgcgc ctgacgcgtc ccgagttata cagaaataat gttgatattt      240

ggaacccatg tcgaacttct atgaagaaag gacaacgatg attgcagcaa gggatttgca      300

ggaatttgtt ccttttggtc gagaccactg caagcaccac cctaatgctt tgaaccttca      360

acttcgccag ctgcagccag cttctgaatt atggtcttct gatggtgctg ctggcttggt      420

gggatccctt caggaggtta caatccacga gaaacagaag gaaagctggc agttaaggaa      480

aggagtaagt gaaattggag aagatgtgga ctatgatgag gaactctatg ttgctggaaa      540

tatggtgata tggagcaaag gaagtaaaag ccaggcattg gcagtttata aagcatttac      600

agttgacagt cctgttcagc aggcattgtg gtgtgacttc attatatcac aggataagtc      660

tgaaaaggcc tacagtagca atgaagtaga aaaatgcata tgtatattgc aaagctcatg      720

tattaacatg catagcatag aaggaaagga ttacatagct tcattaccat ttcaggttgc      780

aaatgtttgg cccactaaat atggattgct gtttgaacga agcgcttctt cacatgaagt      840

acctccaggt tcacccagag aacctttacc tactatgttc agcatgctgc acccactaga      900

tgaaataact ccacttgttt gtaaatctgg aagtcttttt ggttcatcac gggtgcaata      960

tgttgtagat catgcaatga aaattgtttt cctcaatact gacccctcta ttgtaatgac     1020

ttatgatgct gttcaaaatg tgcattctgt gtggactctc cggagagtca aatcagagga     1080

agagaatgtt gttttaaagt tctctgaaca ggggggaacc ccacagaatg tggccactag     1140

cagctccctc acagcacatc tcagaagcct ctccaaagga gattcccctg tgacttcacc     1200

tttccagaat tactcctcca ttcacagcca gagtcgctca acctcatcac ccagtctaca     1260

ttctcgctca ccttctattt ccaacatggc agctctaagt cgtgctcatt ctcctgcgtt     1320

aggagtgcac tctttttcag gggtgcaaag gttcaacatt tcaagccata atcagtctcc     1380

aaagagacat agtatttctc attctccaaa tagtaattct aatggctcct ttcttgcacc     1440

agaaacggag ccaattgttc ctgaactgtg tattgaccat ttgtggacag aaacgattac     1500

taatataaga gagaaaaatt cacaagcctc aaaagtgttt attacatctg acctatgtgg     1560

gcaaaagttc ctgtgctttt tagtagagtc ccagctccag ttacgctgtg taaagtttca     1620

agagagtaat gataaaaccc agctcatctt tggttcagtg accaacatac cagcaaagga     1680

tgcagcacca gtggagaaaa tagacaccat gctggtcttg gaaggcagtg gaaacctggt     1740

gctatacaca ggagtggttc gggtgggaaa ggtttttatt cctggactgc cagctccctc     1800

tctgacgatg tccaacacaa tgcctcggcc cagtactcca ctagatggcg ttagtactcc     1860

aaagcctctt agtaaactcc ttggatcatt ggacgaggtt gttctgttgt ccccagttcc     1920

agaactgagg gattcttcaa aacttcatga ttctctctat aatgaggatt gtactttcca     1980

acagcttgga acttacattc attctatcag agatcctgtc cataacagag tcaccctgga     2040

actgagtaat ggctccatgg ttaggatcac tattcctgaa attgccacct ctgagttagt     2100

acaaacgtgt ttgcaagcaa ttaagtttat cctgccaaaa gaaatagcag ttcagatgct     2160

tgtcaagtgg tacaatgtcc acagtgctcc aggaggaccc agttatcact cagagtggaa     2220

tttatttgtg acttgtctca tgaacatgat gggttataac acagaccgct tagcatggac     2280

tagaaatttt gactttgaag gatcactttc tcctgtcatt gcgcccaaaa aagcaaggcc     2340

ttccgagact ggatctgatg atgactggga atatttacta aattcagact accaccagaa     2400

tgttgagtct catcttttga acagatcttt atgtctgagt ccttcagaag cttcacagat     2460

gaaggatgag gatttttcac agaatctcag tctggattct tctacacttc tctttactca     2520

catacctgca atttttttcg ttcttcacct tgtgtatgag gagcttaagt tgaatactct     2580

aatgggagaa ggaatttgtt cacttgttga acttctcgtt cagttggcaa gggacttaaa     2640

attggggcct tatgtagatc attactatag agactaccca acgcttgtca gaactactgg     2700

acaagtgtgc acaattgatc caggtcaaac aggatttatg catcatccat cattttttac     2760

gtctgagcca ccaagtattt atcagtgggt gagttcttgt ctgaagggtg aaggaatgcc     2820

accttatcct tacctccctg gaatctgtga aagaagcaga cttgtagtct tgagtattgc     2880

actgtacata cttggtgatg agagcttggt ttctgatgaa tcctcacagt atttaaccag     2940

aataactata gccccccaga agttgcaagt agaacaagag gaaaacaggt ttagtttcag     3000

gcattctaca tctgtttcta gtctagctga aagattggtt gtctggatga ctaatgtagg     3060

attcacttta agagatttgg aaactcttcc ctttggaatt gctcttccca tcagagatgc     3120

aatttatcac tgtcgtgagc agcctgcctc agactggcca gaagctgtct gtctcttgat     3180

tggacgtcag gatctttcca agcaggcctg cgaaggaaac ttacccaaag ggaagtctgt     3240

gctctcatca gatgttcctt caggaacaga aactgaggag gaagatgacg gcatgaatga     3300

catgaatcac gaggtcatgt cattaatatg gagtgaagat ttaagggtgc aggatgtgcg     3360

aaggcttctt cagagtgcgc atcctgtccg tgtcaacgta gtgcagtacc cagagctcag     3420

tgaccacgag ttcatcgagg aaaaggaaaa cagattgctc caattgtgtc agcgaactat     3480

ggctcttcct gtaggacgag gaatgtttac cttgttttcg taccatcctg ttccaacaga     3540

gccattgcct attcctaaat tgaatctgac tgggcgtgcc cctcctcgga acacaacagt     3600

agaccttaat agtggaaaca tcgatgtgcc tcccaacatg acaagctggg ccagctttca     3660

taatggtgtg gctgctggcc tgaagatagc tcctgcctcc cagatcgact cagcttggat     3720

tgtttacaat aagcccaagc atgctgagtt ggccaatgag tatgctggct ttctcatggc     3780

tctgggtttg aatgggcacc ttaccaagct ggcgactctc aatatccatg actacttgac     3840

caagggccat gaaatgacaa gcattggact gctacttggt gtttctgctg caaaactagg     3900

caccatggat atgtctatta ctcggcttct tagcattcac attcctgctc tcttaccccc     3960

aacgtccaca gagctggatg ttcctcacaa tgtccaagtg gctgcagtgg ttggcattgg     4020

ccttgtatat caagggacag ctcacagaca tactgcagaa gtcctgttgg ctgagatagg     4080

acggcctcct ggtcctgaaa tggaatactg cactgacaga gagtcatact ccttagctgc     4140

tggcttggcc ctgggcatgg tctgcttggg gcatggcagc aatttgatag gtatgtctga     4200

tctcaatgtg cctgagcagc tctatcagta catggttgga ggacataggc gctttcaaac     4260

aggaatgcat agggagaaac ataaatcacc aagttatcaa atcaaagaag gagataccat     4320

aaatgtggat gtgacttgtc caggtgctac tctagctttg gctatgatct acttaaaaac     4380

caataacaga tctattgcag attggctccg agcccctgac accatgtatt tgttggactt     4440

tgtgaagcca gaatttctct tgcttaggac acttgctcga tgcctgattt tgtgggatga     4500

tattttacca aattccaagt gggttgacag caatgttcct caaattataa gagaaaatag     4560

tatctctctc agtgaaatcg aattgccgtg ctcagaggat ttgaatttgg aaactttgtc     4620

ccaagcacat gtctacataa ttgcaggagc ctgcttgtct ctgggttttc gatttgctgg     4680

ctcagaaaac ttatcagcat ttaactgttt gcataaattt gccaaagatt ttatgactta     4740

tttgtccgca cctaatgctt ctgttacagg tcctcataac ctagaaactt gtctgagcgt     4800

ggtgctgctg tctctcgcca tggtcatggc tggctcagga aacctaaagg ttttgcagct     4860

ttgtcgcttc ttacacatga aaacgggtgg tgaaatgaac tatggttttc acttagccca     4920

ccacatggcc cttggacttc tatttttggg aggaggaagg tactctttga gcacatcaaa     4980

ttcttccatt gccgctcttc tctgtgccct ttatccgcac ttcccagctc acagcactga     5040

caaccggtat catctccagg ctctccggca cctctatgtg ctggccgcgg agcccaggct     5100

tctagtgcct gtggatgtgg acacaaacac gccctgctat gccctcttag aagttaccta     5160

caagggcact cagtggtatg aacaaaccaa agaagaattg atggctccta cccttcttcc     5220

agaactccat cttttaaagc agattaaagt aaaaggccca agatactggg aactgctcat     5280

agatttaagc aaaggaacac aacacttgaa gtccatcctt tccaaggatg gggttttata     5340

tgttaaactc cgggcgggtc agctctccta caaagaagat ccaatgggat ggcaaagttt     5400

gttggctcag actgttgcta acaggaactc tgaagcccgg gctttcaagc cagaaacaat     5460

ctcagcattc acttctgatc cagcacttct gtcatttgct gaatatttct gcaagccaac     5520

tgtgaacatg ggtcagaaac aggaaattct ggatctcttt tcttcagtac tctatgaatg     5580

tgttacccag gagaccccag agatgttgcc tgcatacata gcaatggatc aggctataag     5640

aagacttggg agaagagaaa tgtctgagac ttctgaactt tggcagataa agttggtgtt     5700

agagtttttc agctcccgaa gccatcagga gcggctgcag aaccacccta agcgggggct     5760

ctttatgaac tcggaattcc tccctgttgt gaagtgcacc attgataata ccctggacca     5820

gtggctacaa gtcgggggtg atatgtgtgt gcacgcctac ctcagcgggc agcccttgga     5880

ggaatcacag ctgagcatgc tggcctgctt cctcgtctac cactctgtgc cagctccaca     5940

gcacctgcca cctataggac tagaagggag cacaagcttt gctgaactgc tcttcaaatt     6000

taagcagcta aaaatgccag tgcgagcttt gctgagattg gctcctttgc ttcttggaaa     6060

tccacagcca atggtgatgt gaccgtgtct ggcggtgaac ctaccctgaa acgtgacttc     6120

tgcacaacaa acgtgaccaa acatcaaagc taaagcaatg tttataaagt tttatggtat     6180

aactaggggg aaatgagctg cacaaacctc aatgtatttt aaatctgttg ctgtcatcat     6240

taacggtata tgacatataa aagcaagtta aaatttactt ttgtaaataa agtttttggt     6300

ttgtttccaa aactcttgat gattgcttta gttttggact tagagaatag agcaggggtt     6360

gctggagtga atattgattt ttaaagtctt tgaactgtgg tggtataggt gaagtgacta     6420

tgcccaaaaa tgccaagttt taaaagaagc tatgtcataa agttttactt tctgtggcaa     6480

aagagcgctt tagcatttcc tcagatgtca cagttgtcct gtctaaaata agtttgtact     6540

tctggtgaca atgccagaca ctcttatgat gtgatcacct taaacaggag aaggagattt     6600

ttgccctcag ttgctcaaca tgaagtactg tggactgaat tgtgtcctcc cagaattata     6660

tattgaggcc ctaatccctg tgtgactgta ttaggcaata gggcatatag gagattacta     6720

aggttaagtg aggtcatcat aagggtgggg ccttaattca gtagaattgg tggcctccta     6780

agcagaggaa gagagatttt tctttctctc tctgccatgt gaagacagtg aggagtcggc     6840

cgtctgcaag ccaagaagag cccttatcag gaacagactt ggctagcacc ttcatcgtgg     6900

acctccagcc tccagaattg caagaaaata catttccgtc gttgaaacca cccagtctgt     6960

ggtattttgt tatggcagcc caggcagact aatacgtgaa gcctgctcta aatagataaa     7020

ataagaaatt actacagagg gctctttaga aattgtattt aaaaacaaga caatccatat     7080

ttacctaaga tttacagaat gtatgtctat aaaaggaggg atttctggac tagatgatga     7140

tgaaaaatgt tcatataaag gcacctccag cttcgagttg ccaacacagg aggaagaatg     7200

ctccctgctg ttcagatgct gatatgtgtc ctgtgcttcc tggatggcca gtgggatcat     7260

aagctggtag aagcaagacc ttcatccact gacttcatat ttcttccaca tcctgaactg     7320

tggtgtttga ctttaaaaat aaattaaagc aaatagaaat gtttccattg agattttggc     7380

aaaaacccac atgacatttg cgtctgcaga gtagacttgg aaggcatgca cctggaggcc     7440

aagtggtatt ctctggactc tctgtccttg catttgcgtg gctgccccga ggactcgctt     7500

cttcctggat gtgaagcaga ggcacgatgg ggctgactga gaggctgaaa tgtgcttctc     7560

ttcacagtta catagttttc ttctaattaa aaataaattt taagtggtag attatgaaaa     7620

ttccatttga atcaagattt taaaaattca atatcaaacc agttgttact gtcttcactc     7680

tccgttgttt acgattgtgt gcttttcctg aataaagaat gactggagag acattaaaaa     7740

aaaaaaaaaa aaa                                                        7753


<210>  1830
<211>  4846
<212>  DNA
<213>  homo sapiens

<400>  1830
gagcggtgct caggggaggg ctggagggga gggaaggaga gagagagggg agggcggcac       60

cgcccctagc cccgcgctcc ggaagtgaag cggccagacc accagctaat ggatgcggag      120

cggagggccc gctgaccgct ctccgcgcct ggagcagctt ggcttggctg gagctaagag      180

ccagacacac cactgtgtgg aggtgggtga tgtcttcctg tgctaaaagg tgaataaata      240

agctcctcac ctctcgcgga acactcggga acacatcaac aggggtccaa gccgccctgc      300

tgggaggctt ctcttcaaga gttctgggtc ccagagtgga aggcattttc ccatcaactg      360

gagagagacg aaacatcaga gaccaggagg ctgtggagaa agcagctgtc ccaggtgcct      420

caactatcag agaagggtca gcgtcacgtg gctgccagca tctttgagaa aatcactggc      480

aatcggactt cagagctgcg ggcacaggtg tggttagaac tgagatacga cctgcccacc      540

tgggtcaggc ctaaagacaa gaagtcctga gttcttgcca ctgagtaggc cagggtcatt      600

tgtccagaaa actttgtgac tgtctttgag tgacctagtc tgggacccat tcattggtgg      660

gttctaaggt tagaagctca tccaggatat tttcaatatt aagtcagtgc atagctgcac      720

cactaacaaa ttggtgcctg tagagtcaga gtgggtcaat tcttaggaca atggcgctgg      780

cactgttaga ggactggtgc aggataatga gtgtggatga gcagaagtca ctgatggtta      840

cggggatacc ggcggacttt gaggaggctg agattcagga ggtccttcag gagactttaa      900

agtctctggg caggtataga ctgcttggca agatattccg gaagcaggag aatgccaatg      960

ctgtcttact agagcttctg gaagatactg atgtctcggc cattcccagt gaggtccagg     1020

gaaagggggg tgtctggaag gtgatcttta agacccctaa tcaggacact gagtttcttg     1080

aaagattgaa cctgtttcta gaaaaagagg ggcagacggt ctcgggtatg tttcgagccc     1140

tggggcagga gggcgtgtct ccagccacag tgccctgcat ctcaccagaa ttactggccc     1200

atttgttggg acaggcaatg gcacatgcgc ctcagcccct gctacccatg agataccgga     1260

aactgcgagt attctcaggg agtgctgtcc cagccccaga ggaagagtcc tttgaggtct     1320

ggttggaaca ggccacggag atagtcaaag agtggccagt aacagaggca gaaaagaaaa     1380

ggtggctggc ggaaagcctg cggggccctg ccctggacct catgcacata gtgcaggcag     1440

acaacccgtc catcagtgta gaagagtgtt tggaggcctt taagcaagtg tttgggagcc     1500

tagagagccg caggacagcc caggtgaggt atctgaagac ctatcaggag gaaggagaga     1560

aggtctcagc ctatgtgtta cggctagaaa ccctgctccg gagagcggtg gagaaacgcg     1620

ccatccctcg gcgtattgcg gaccaggtcc gcctggagca ggtcatggct ggggccactc     1680

ttaaccagat gctgtggtgc cggcttaggg agctgaagga tcagggcccg ccccccagct     1740

tccttgagct aatgaaggta atacgggaag aagaggagga agaggcctcc tttgagaatg     1800

agagtatcga agagccagag gaacgagatg gctatggccg ctggaatcat gagggagacg     1860

actgaaaacc acctgggggc aggacccaca gccagtgggc taagaccttt aaaaaatttt     1920

tttctttaat gtatgggact gaaatcaaac catgaaagcc aattattgac cttccttcct     1980

tccttccttc cctcccttcc tccttctctc cttctctcct cctctctcct ctcctctcct     2040

ctctttcctt ccttccttcc ttttttcttt ttctctttct tctttatttc ttgggtctca     2100

ctctcatcac ccaggctaga gtgcagtggc acaaaaatct cggctcactg cagccttgac     2160

ttcccaggct caggctcagg tgatcctcac accttagcct cccaagtacc tgggactaca     2220

ggcacgcacc accatgccta gctattcttt tgtatttttg gtagagacag ggttttgctg     2280

tgttgctcag gctggtctgg aacccctagg ctcaaatgat gtgcccaact cggcctccca     2340

aagtgctggg attacaggca tgaaccgcca tgcctggccc ttgatttttc tttttaagaa     2400

aaaaatatct aggagtttct tagaccctat gtagattatt aatgaacaaa agattaaact     2460

ccaaatatta aatagtaagc ctgaaggaat ctgaaacact tgtacttcca attttcttta     2520

aataatccca aatagaccag aattggccca taccatagaa gaaagaattg gcagtcaaaa     2580

aaaaaaatac cttttgtaat gtttgaaaaa taaagctgtt tgacttgtca ggtgttttcc     2640

tttctcaaat cagcaaattc tctctgagtg cctggctttg tgagacactg tacaaggagt     2700

tacaagacta cagctataac ctgcagttga gcagttataa acctacaaaa tgggccctgc     2760

cctcagagag gttccagtct agatgaggag ctgatctaga caggtaaaag gctaactaac     2820

cctttgtgta aataagttca tcaccccagt aaaagtgtca tcacccagtg aataggacca     2880

cctctgcctg cagatttttg ttgttgttgt tgtcattgtt gttgttgttt taacctggga     2940

agtgttcttc ctgcctttct gctaggtgtc agatagatgg tcccagagct aggtgctgtg     3000

tcaggccctg aagacacaga tgactcaacc taagctttac tttccagagg tccacagcct     3060

gagaggtgtc cccaaagaaa gggggacatg aggggactgc atgcttgaga gcagggttgt     3120

ttagggcagg tttggattta gtgagcaggc tggtttgctt agagaaggct tttagtggca     3180

acaaaggatg aagaggagag aaaaggaact cacatttatt gagggcctac tgtgtgcaaa     3240

gtgtttcatg tatatctcat tgaatgtata cagccaccct gttgtggtat aattttgctc     3300

tttataaaga gaaagaccga agctcagatg agttaagtgg tctcctcaac accaaaatgc     3360

caagaagtga tggagcctag acagaagccc agaactttct gactcacact agtccatcct     3420

ctaccatcac gatgactttc aaattgtgct ctgcagttct gcagattttc tagcagtgcc     3480

atctccaaaa tgtgttttaa actctttatt tttttaatta ttattagtat tattttgaga     3540

ctgagtcttg ctctatcacc caggctggag tgcagtggtg caatctcagc tcactgcaac     3600

ctccgcctcc caggttcaag cgatttcgtg cctcagcctc ccgagtagct gggattacag     3660

gcacccacca ccacgcccag ctaatttttg tatttttagt agaaatgggg tttcaccatg     3720

ttggccaggc tggtctcgaa ctcctgacct caagtgatcc actcacctcg gcctcccaaa     3780

gtgctgggat tacaggtgtg agccaccatg cctgggctaa actctttaag tctctagtaa     3840

atgcagctag attcaaatgg gctgataacc aaattttaac acatcagcat tcaccaccag     3900

gtttactttt attttcagat tggctcattt tgtgcagacc ttagagcaaa gtttccttta     3960

tggtatctgt gtacgtatcc aaacttcttt taattgttca cagattttaa aagcggtagc     4020

accacatggt tgtgtagatc agacctgtgt atttagatca gacctgtgta tcacgtaagt     4080

gtgtgagtgc agtgcagatg agcaccattt agttatatgt gctaggcaaa tctccaacac     4140

agttgatgtg tagtcttgtg gtagatttgt gcatactgta agcaaattgc ttagcttctc     4200

tagacatcag tttccacatc tgaaaaataa gaagatgaga gtacacggtt gttatgaaca     4260

aatgacttaa tgctttttaa gcacgttgca tgacatctgg aacacagaaa gccctcaata     4320

cattgaagct cttaggattt tcacgatgtt cctgtctgct caatgcatgc tttctttatt     4380

gttctgacag ttgtgtggta acaagctaat atgcttccag ttgacttcca gtctaccctg     4440

gtgttagaaa ccgtttcatc tcttattgta aatttgagtg cttgttgttt tttatatttg     4500

tgatgactct tccagcagtt gttgacaatt gttagaggtt tgacttttaa ataattactt     4560

attttttctg attgtggttc agtttaactg aagaatatcc tgagattgta agaaaagcat     4620

tttttaaaag gtatcacttg tgatcattta tctttctaaa ttctattttt aatactgttc     4680

caccaaagtg atgcagtggt taccatgaca ccctaatttc atgtgttttt gtatttatga     4740

aaatagtttc attgtcattt attggcggta tacaaagtaa aatgttataa atgtgaagtt     4800

ataaaataaa tatatgctaa taaaatcctg agtttttctg tttcct                    4846


<210>  1831
<211>  3777
<212>  DNA
<213>  homo sapiens

<400>  1831
gtctttacgt agacgtcggg ggcgcagccg cgctgtgcgc ggtgactggc ggctgcactg       60

gcggcagctg gaggtgtaat agtgcgggta gtgggtttgg agaagttccg aggcggcggt      120

ggcgccggtc aggacaagga tagcggaacc gggccctggg cttgtcgctc accatgccga      180

cagtagagga gctttaccgc aattatggca tcctggccga tgccacggag caagtgggcc      240

agcataaaga tgcctatcaa gtgatattgg atggtgtgaa aggtggtact aaggaaaagc      300

gattagcagc tcaatttatt ccgaaattct ttaagcattt tccagaattg gctgattctg      360

ctatcaatgc acagttagac ctctgtgagg atgaagatgt atctattcga cgtcaagcaa      420

ttaaagaact gcctcaattt gccactggag aaaatcttcc tcgagtggca gatatactaa      480

cgcaactttt gcagacagat gactctgcag aatttaacct agtgaacaat gccctattaa      540

gtatatttaa aatggatgca aaagggactt taggtgggtt gttcagccaa atacttcaag      600

gagaggacat tgttagagaa cgagcaatta aattcctttc tacaaaactt aagactttac      660

cagatgaagt cttaacaaag gaagtggaag agcttatact aactgaatcc aaaaaggtcc      720

tagaagatgt gactggtgaa gaatttgttc tatttatgaa gatactgtct gggttaaaaa      780

gcttacagac agtgagtgga agacagcaac ttgtagagtt ggtggctgaa caggccgacc      840

tagaacagac cttcaatccc tcggatcctg actgtgtgga caggctctta cagtgcactc      900

ggcaggcagt acccctcttc tctaaaaatg tccattccac aaggtttgtg acatatttct      960

gtgagcaggt tctccctaac ctcggtacct tgactacccc agtggaaggt cttgatatac     1020

agttggaggt attgaaattg ttggcggaga tgagttcatt ttgtggtgac atggaaaaac     1080

tagaaacaaa tttaaggaaa ctatttgata agttattgga atacatgccc ctccctccag     1140

aagaggcaga aaatggagag aatgctggta atgaagaacc caagctacag ttcagttatg     1200

tggaatgttt gttgtacagt tttcaccagt tgggccgaaa acttccagat ttcttaacag     1260

ccaaactgaa tgcagaaaag ctcaaagatt tcaaaatcag gctgcagtac tttgcacggg     1320

gcctgcaagt ttatatcaga caacttcgct tagctctcca gggtaaaacg ggtgaggcct     1380

taaaaacaga agagaacaag attaaagtcg ttgcattgaa aataacaaac aatatcaatg     1440

ttttaatcaa ggatctcttc cacattcctc cttcttataa gagcacagta acactatcct     1500

ggaaacctgt acaaaaggtt gagattgggc aaaagagagc cagtgaagat acaacttcag     1560

gttcaccacc caagaaatct tcagcaggac caaaaagaga tgccaggcag atttataacc     1620

ctcccagtgg gaaatatagc agcaatttgg gcaactttaa ttatgagagg agccttcagg     1680

ggaagtagag gtggccgagg ttggggcaca cgaggaaatc gtagtcgggg aagactctac     1740

tgaataagac atcagcattc ttcagcattg tcatgagctt aatatactta aattctacta     1800

ctcattggat tgccggggat gtccctttaa acagactgct gccttcagct aaaaacttaa     1860

tgttctttat acctttgtat gtatgaccta cttttgtaac agaccatggt tgtgtccaag     1920

gtaaaaccac agtgatattt ttggatgctt tgtctgcaat cttgacttgt ttttgcagta     1980

tcattattca gacttcaaat tgtgaatctt ttaaacatct tgataatttg ttgttgagag     2040

ctgttcattc taaaatgtaa tgaaattcag tctagttctg ctgataaaga tcatcagttt     2100

tgaaaggtta ctgattttcc tcttccctct tagtttttta cccaatatat ggagaagagt     2160

aatggtcaat cttaacattt tgttttaatt gtttaataaa gctgctgggc agtggtgcag     2220

cattcctacc tagtgtcata aaagcaaaat acttacatag ctttcttaaa atataggaat     2280

gacattacat ttttaggaga aagtaagttg ctttgcaccg cctacttaat tcttttccat     2340

atattgtgat acaaactttt gaatatggaa tcttactatt tgaatagaaa tgtgtatgta     2400

taatatacat acatacataa gcatatatgt gtgtgtgtgt gtgtatatat atatatatgc     2460

atgctgtgaa acttgactac acaacataaa tcacttttta aattccagga acgggtagtc     2520

tgacacggtg attatccttt tgaggctgaa tccgttatta acttgttatt taggttttta     2580

ctcccagtag caagggattc taagttagtt gcacttacat gattattgtt atttaaaact     2640

aagaataaag gctgcatttt caaagataaa ttggaattgc tgttggtgaa ataacaacca     2700

aaatactgaa tctgatgtac atacaggttt ctacaggaag agatggtata atttacaatt     2760

tggagattta ataaccaggg ctacccagaa aaagtgactt gataacatgg taccaataag     2820

taagggatgc tctctcggtt tgcttttgcc actttcaaga ttttaacttc tcaggttatt     2880

aatcaaaatt attgtataag ttagccaata gaatttttag gttaaaacaa cagatggggg     2940

gtttgtggag tgtttaatgt catgggcatt tttagtagca tagacccttt gttctgcatt     3000

tgaatgtttc gtatattttt gtttcacagt taatcttccc tccccaagtt tgctattcaa     3060

atcaactgcc tgaatgacat ttctagtagt ctgatgtatt tttctgagga atagtttgtg     3120

attccaatgc aggtgtcttc attaccatta cctctacact gcagaagaag caaaactcct     3180

ttattagaat tactgcacat gtgtatgggg aaaatagttc tgaaaggcta gaatgataca     3240

agtgagcaaa agttggtcag cttggctatg gagtggtggc aataatctct aaacattcca     3300

aaagaccatg agctgaacct aaactccctt ggaatctgaa caaaggaata taaaattgcc     3360

atttgaaaac tgaccagcta atctggacct cagagataga tcagccagtg gcccaaagcc     3420

atttcaagta cagaaattat agagactaca gctaaataaa tttgaacatt aaatataatt     3480

ttaccacttt ttgtctttat aagcatattt gtaaactcag aactgagcag aagtgacttt     3540

actttctcaa gtttgatact gagttgactg ttcccttatc cctcaccctt ccccttccct     3600

ttcctaaggc aatagtgcac aacttaggtt atttttgctt ccgaatttga atgaaaaact     3660

taatgccatg gatttttttc ttttgcaaga cacctgttta tcatcttgtt taaatgtaaa     3720

tgtcccctta tgcttttgaa ataaatttcc ttttgtaatt ttgaaaaaaa aaaaaaa        3777


<210>  1832
<211>  4007
<212>  DNA
<213>  homo sapiens

<400>  1832
acttccgctc cacgcagcgc ctgtgctgcc gcgtctcgac gtgtcaccgg cggcgccgct       60

gctgtggcaa aggaaggagc tgactggggg agttcgaggc ggcgggcggc ggtgaccccg      120

gcctggaact gccccggtac ggaagtgttc cggggtccgt ggggagcagg agagggaggc      180

ggcggaccgt cccgcgcggg gcacgatgtt gaacatgtgg aaggtgcgcg agctggtgga      240

caaagccacc aatgttgtta tgaattattc agagatcgag tctaaggttc gagaggcaac      300

gaacgatgat ccttggggac cttctgggca actcatggga gagattgcca aggctacatt      360

tatgtatgaa caatttccag aacttatgaa catgctttgg tcacgaatgt taaaagacaa      420

caaaaagaat tggagaagag tttataagtc gttgctgctc ctagcttacc tcataaggaa      480

tggatcagag cgtgttgtta caagtgccag agaacacatt tatgatttac gatccctgga      540

aaattaccac tttgtagatg agcatggtaa ggatcaaggt ataaatattc gacagaaggt      600

gaaggaattg gttgaatttg cccaggatga cgacaggctt cgtgaagagc gaaagaaagc      660

aaagaagaac aaagacaagt atgttggggt ttcctcagac agtgttggag gattcagata      720

cagtgaaaga tatgatcctg agcccaaatc aaaatgggat gaggagtggg ataaaaacaa      780

gagtgctttt ccattcagtg ataaattagg tgagctgagt gataaaattg gaagcacaat      840

tgatgacacc atcagcaagt tccggaggaa agatagagaa gactctccag aaagatgcag      900

cgacagcgat gaggaaaaga aagcgagaag aggcagatct cccaaaggtg aattcaaaga      960

tgaagaggag actgtgacga caaagcatat tcatatcaca caggccacag agaccaccac     1020

aaccagacac aagcgcacag caaatccttc caaaaccatt gatcttggag cagcagcaca     1080

ttacacaggg gacaaagcaa gtccagatca gaatgcttca acccacacac ctcagtcttc     1140

agttaagact tcagtgccta gcagcaagtc atctggtgac cttgttgatc tgtttgatgg     1200

caccagccag tcaacaggag gatcagctga tttattcgga ggatttgctg actttggctc     1260

agctgctgca tcaggcagtt tcccttccca agtaacagca acaagtggga atggagactt     1320

tggtgactgg agtgccttca accaagcccc atcaggccct gttgcttcca gtggcgagtt     1380

ctttggcagt gcctcacagc cagcggtaga acttgttagt ggctcacaat cagctctagg     1440

cccacctcct gctgcctcaa attcttcaga cctgtttgat cttatgggct cgtcccaggc     1500

aaccatgaca tcttcccaga gtatgaattt ctctatgatg agcactaaca ctgtgggact     1560

tggtttgcct atgtcaagat cacagaatac agatatggtc cagaaatcag tcagcaaaac     1620

cttgccctct acttggtctg accccagtgt aaacatcagc ctagacaact tactacctgg     1680

tatgcagcct tccaaacccc agcagccatc actgaataca atgattcagc aacagaatat     1740

gcagcagcct atgaatgtga tgactcaaag ttttggagct gtgaacctca gttctccatc     1800

gaacatgctt cctgtccggc cccaaactaa tgctttgata gggggaccca tgcctatgag     1860

catgcccaat gtgatgactg gcaccatggg aatggcccct cttggaaata ctccgatgat     1920

gaaccagagc atgatgggca tgaacatgaa catagggatg tccgctgctg ggatgggctt     1980

gacaggcaca atgggaatgg gcatgcccaa catagccatg acttctggaa ctgtgcaacc     2040

caagcaagat gcctttgcaa atttcgccaa ttttagcaaa taagagattg taaaagaagc     2100

agattgaatg aagaattttt agctgtgcag ataggtgatg ttgggatgga aaatgctaat     2160

caactaccct ttcttttatc aagtaattaa aataaatcta cataaagaac caaaaaggct     2220

gttttataaa agtgaaatat ccagtatttc agagggccag gcaagagcac ttcagatgag     2280

gcagtcaaaa tcattttttt ccagtgagga tagaccacaa gtgggtggtg agaccattga     2340

aagcctttat caactgaaga gtccatttaa cagcataatt tgtgggaaga ctggaatagg     2400

gctgaataaa tgtgtttgaa tctctaattt tatactttct tttcctgagg aacttgattt     2460

ttctgtccct ggatcgcctt gtcataattg ggtctgttcc ttttactacc actcttgagt     2520

ccatatatga aatcattaaa gttggatgat cagtttttta taaaaatata tatttttgtc     2580

caagaaaaaa aaaagcatac atatgtgatt atggctaaat caaaggtaac tggaatgtat     2640

atacttttgc taatgttcca gcaacactgc tattatacta tccaaatttt tattgtaaca     2700

aaacctcttt aagcaattgg tgattgccat gggacttttc ccatgtcttc tgctgtaatt     2760

atcctgtgca gaactaggaa gaaatttttt tcaggactgc tctatggttt cctttaaaag     2820

aaaaaaactt ctgtttgttt ttagcagtca ttatttacaa tttgcagtga ttaacttggc     2880

aaggcttcct tccgtgttta tccctgtagc catcatttaa gtcaggaaca gtcagaaaaa     2940

tatttatttt attttttttt tgggtgtctg caaaggtaaa aatccattaa aaccttaagt     3000

taaatataaa tgttacaact caatgtttgc ttttagattt tatacagtat ttgttttgtt     3060

ttggttttga gtgtatataa tgcagcatta gcaatatggt tccaatagag gagttaaata     3120

tatattgtta aaggagacct gtagcagtca aagattttat tgatttaatg acaaaggaaa     3180

ttaatgaaaa tgtttttgtt tttctgctgt aattctgcat taagctcaca tgaaaatcat     3240

gattctagag tttggaatgc aaaattaatt gttttaccct caagctggga atatttttca     3300

aaataaatac tataatatag atatcaaatt attacctccc catgttatgt tgaaaatttt     3360

tttattaaat tgataaaact ttatttccat tatattcata atgttctgtt atacataaca     3420

ttaaaatgtt cattaaaatc aatgttgaac tgctttttct ttcgttctgt tagacatttg     3480

agaccatttg gggaaaaaat aattatagtt tgggcaaagt aatttttata aataatttaa     3540

aattatttaa tgacttctct attctttcct atcagactct actgttagga attaaaaatg     3600

aagcagcaaa gatatcctga cctgctccat tcttgctaat gttccatcta caacatttct     3660

aattaggcag aaattcatgt acttcagcta agtggtaatg aaaagtgatt catttgctga     3720

ataagagatg agagtgagtg taattagctg actgcggttt ttaatctttc aacaattcaa     3780

tgtgtttaac ttagtttcaa agaataggag ctttcaagtg ttgttacttc agagcaatca     3840

agccagcctc tggtggccgc atagtagaat atggtccctg atatttaaaa ccgatcatct     3900

taagtaaatt ttttctttaa gaagtatatc ttcactttct caaatatgta tggttcttag     3960

acgaagtaaa tgtttatctg aaccttaaaa aaaaaaaaaa aaaaaaa                   4007


<210>  1833
<211>  1829
<212>  DNA
<213>  homo sapiens

<400>  1833
atcccagtgg gtggcagctg gaggcggggc accctgaggg gcggggaagg actagggtgc       60

ggggaggggg ttgcaaaagg agccgagcgg cttctgctca atggcggaaa agccgccggt      120

gctctgacgg cctcgttccc ctagcagttg cgggggagtt tcctgccggc gcggctggag      180

tctctgattc tcagggttcg gtggttggaa gatgctccag agagacgagg ctgcggcgga      240

ggaggtggcg gcggccgaat cggcaacggc gctagggtgg agagaaggcg gcatcggcgg      300

cggcggcggc gtgaggggcc gggcggtgta aacagccccg gaggcggcgg tcgagacccc      360

gagggggaag cggcggctga gtcagggtcg cgcctccgtt ggaaacttgg gctgagtacc      420

gcggcgggcg cgagcgaggc gccctagaca tcttctccct cccttgcctc agggaagtcg      480

agataacatg agtattgtac tagtttgctt ttcaaatgct cccaaggtct cagatgaagc      540

ggtgaaaaaa gattcagagt tggataagca cttggaatca cgggttgaag agattatgga      600

gaagtctggc gaggaaggaa tgcctgatct tgcccatgtc atgcgcatct tgtctgcaga      660

aaatatccca aatttgcctc ctgggggagg tcttgctggc aagcgtaatg ttattgaagc      720

tgtttatagt agactgaatc cacatagaga aagtgatggg gcctccgatg aagcagagga      780

aagtggatca cagggaaaat tggtggaagc tctcaggcaa atgagaatta atcatagggg      840

aaactaccga caacttctgg aggagatgct gactagttac aggctagcta aagtagaggg      900

agaagaaagc cctgctgaac cagctgccac agctacttct tcgaacagtg atgctggaaa      960

cccagtgaca atgcaggaaa gccatactga atcagaaagt ggtcttgctg aattagacag     1020

ctctaatgaa gatgcaggga caaagatgag tggtgaaaaa atatgacttt cctttttggt     1080

aatatttttg tgatctttga tggtttttaa cctaggaagt gtaatgtatg catttatata     1140

actgttttgt tatttgaatc ttggaaaact agttttatta tattcagata gccttgtttt     1200

ttaaaaaggc ctttgcatac acctttatga gatagtgtaa aattgactat ttatagtact     1260

atggatttaa tgaaattata tgtcatttca cattgtatgc cagaaattag gctaccaatt     1320

atgaattaaa gtcagtagtt aaattaatac tagatagaat tagaaatttt gattagagag     1380

attatgctat attatggaaa aacttgttaa tgtagaatta tactgcttca tattatttta     1440

cctattagta cactcatagt tagctttgta ataaatttat gttttcttta ataattttag     1500

ttcttcaaag aatggctgat gctggcctgt aatttttctt tcaaggatga taatttgtgt     1560

gttgtttgat ttgtttatat tttacatctc tgtagtttta tttttagaag ttgtgagata     1620

ttggatgtgt ggctattttt cctttctctg tattctttat gaaacataac ttttgaaaaa     1680

cctatgtatt attcatacag ctttggtttg tatattctgt atagcctaac tacacacatc     1740

aaaatgtatg tcaaccaagt gtttagaatg aaattataag tgtttaagtc caaataaagc     1800

atgtgatgtg gaataatcta taaaaaaaa                                       1829


<210>  1834
<211>  1176
<212>  DNA
<213>  homo sapiens

<400>  1834
aatagtgatt aggaaacctt gaagcctgcc caacgatcgt gggcaggagg tggtttctgg       60

tttgttgggg cgtgtgtatg tgtatttggg gggactgaag ggtacgtggg gcgaaacaaa      120

accggccatg gcagcagcgg aggaggagga cgggggcccc gaagggccaa atcgcgagcg      180

gggcggggcg ggcgcgacct tcgaatgtaa tatatgtttg gagactgctc gggaagctgt      240

ggtcagtgtg tgtggccacc tgtactgttg gccatgtctt catcagtggc tggagacacg      300

gccagaacgg caagagtgtc cagtatgtaa agctgggatc agcagagaga aggttgtccc      360

gctttatggg cgagggagcc agaagcccca ggatcccaga ttaaaaactc caccccgccc      420

ccagggccag agaccagctc cggagagcag agggggattc cagccatttg gtgataccgg      480

gggcttccac ttctcatttg gtgttggtgc ttttcccttt ggctttttca ccaccgtctt      540

caatgcccat gagcctttcc gccggggtac aggtgtggat ctgggacagg gtcacccagc      600

ctccagctgg caggattccc tcttcctgtt tctcgccatc ttcttctttt tttggctgct      660

cagtatttga gctatgtctg cttcctgccc acctccagcc agagaagaat cagtattgag      720

ggtccctgct gacccttccg tactcctgga cccccttgac ccctctattt ctgttggcta      780

aggccagccc tggacattgt ccaggaaggc ctggggagga ggagtgaagt ctgtgcatag      840

atgggagagc cttctgctca gaggctcact cagtaacgtt gtttaattct ctgccctggg      900

gaaggaggat ggattgagag aatgtctttc tcctctccta agtctttgct ttccctgatt      960

tcttgatttg atcttcaaag gtgggcaaag ttccctctga ctcttccccc actccccatc     1020

ttactgattt aatttaattt ttcactcccc agagtctaat atggattctg actcttaagt     1080

gcttccgccc cctcactacc tcctttaata caaattcaat aaaaaaggtg aaatataaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                               1176


<210>  1835
<211>  2447
<212>  DNA
<213>  homo sapiens

<400>  1835
ggggcggggc tggcggcgcc ggcgcagccc gggggcggcg ggaggaggag gtggcggcgg       60

tggcgctggg agctcctgtc accgctgggg ccgggccggg cgggagtgca ggggacgtga      120

gggcgcaagg gccgggacat ggggcccgcc agccccgctg ctcgcggtct aagtcgccgc      180

ccgggccagc cgccgctgcc gctgctgctg ccactattgc tgctgcttct gcgcgcgcag      240

cccgccatcg ggagcctggc cggtgggagc cccggcgcgg ccgaggcccc ggggtcggcc      300

caggtggctg gactatgcgg gcgcctaacc cttcaccggg acctgcgcac cggccgctgg      360

gaaccagacc cacagcgctc tcgacgctgt ctccgggacc cgcagcgcgt gctggagtac      420

tgcagacaga tgtacccgga gctgcagatt gcacgtgtgg agcaggctac gcaggccatc      480

cccatggagc gctggtgcgg gggttcccgg agcggcagct gcgcccaccc ccaccaccag      540

gttgtgccct tccgctgcct gcctggtgaa tttgtgagtg aggccctgct ggtgcctgaa      600

ggctgccggt tcttgcacca ggagcgcatg gaccaatgtg agagttcaac ccggaggcat      660

caggaggcac aggaggcctg cagctcccag ggcctcatcc tgcacggctc gggcatgctc      720

ttaccctgtg gctcggatcg gttccgtggt gtggagtatg tgtgctgtcc ccctccaggg      780

acccccgacc catctgggac agcagttggt gacccctcca cccggtcctg gcccccgggg      840

agcagagtag agggggctga ggacgaggaa gaggaggaat ccttcccaca gccagtagat      900

gattacttcg tggagcctcc gcaggctgaa gaggaagagg aaacggtccc acccccaagc      960

tcccatacac ttgcagtggt cggcaaagtc actcccaccc cgaggcccac agacggtgtg     1020

gatatttact ttggcatgcc tggggaaatc agtgagcacg aggggttcct gagggccaag     1080

atggacctgg aggagcgtag gatgcgccag attaatgagg tgatgcgtga atgggccatg     1140

gcagacaacc agtccaagaa cctgcctaaa gccgacagac aggccctgaa tgagcacttc     1200

cagtccattc tgcagactct ggaggagcag gtgtctggtg agcgacagcg cctggtggaa     1260

acccacgcca cccgcgtcat cgcccttatc aacgaccagc gccgggctgc cttggagggc     1320

ttcctggcag ccctgcaggc agatccgcct caggcggagc gtgtcctgtt ggccctgcgg     1380

cgctacctgc gtgcggagca gaaggaacag aggcacacgc tgcgccacta ccagcatgtg     1440

gccgccgtgg atcccgagaa ggcacagcag atgcgcttcc aggtgcatac ccaccttcaa     1500

gtgattgagg agagggtgaa tcagagcctg ggcctgcttg accagaaccc ccacctggct     1560

caggagctgc ggccccaaat ccaggaactc ctccactctg aacacctggg tcccagtgaa     1620

ttggaagccc ctgcccctgg gggcagcagc gaggacaagg gtgggctgca gcctccagat     1680

tccaaggatg acacccccat gacccttcca aaagggtcca cagaacaaga tgctgcatcc     1740

cctgagaaag agaagatgaa cccgctggaa cagtatgagc gaaaggtgaa tgcgtctgtt     1800

ccaaggggtt tccctttcca ctcatcggag attcagaggg atgagctggc accagctggg     1860

acaggggtgt cccgtgaggc tgtgtcgggt ctgctgatca tgggagcggg cggaggctcc     1920

ctcatcgtcc tctccatgct gctcctgcgc aggaagaagc cctacggggc tatcagccat     1980

ggcgtggtgg aggtggaccc catgctgacc ctggaggagc agcagctccg cgaactgcag     2040

cggcacggct atgagaaccc cacttaccgc ttcctggagg aacgaccctg acccggcccc     2100

cttcacccct tcagccgagc ccagacctcc cctcttcctg gagccccaga accccaactc     2160

ccagcctagg gcagcaggga gtcttgaagt gatcatttca cacccttttg tgagacggct     2220

ggaaattctt atttcccctt tccaattcca aaattccatc cctaagaatt cccagatagt     2280

cccagcagcc tccccacgtg gcacctcctc accttaattt attttttaag tttatttatg     2340

gctctttaag gtgaccgcca ccttggtcct agtgtctatt ccctggaatt caccctctca     2400

tgtttcccta ctaacatccc aataaagtcc tcttccctac caggcca                   2447


<210>  1836
<211>  2519
<212>  DNA
<213>  homo sapiens

<400>  1836
aatcttggtc gctaggacac ggctaacttc cgctttcttc cccctctcct aggctcaaac       60

tagtcaaatc ttgttcactc gaccaatggc aaatcggaag tgggcgggac ttcacaagtc      120

cggaccaaag aaacgcgagc ttagccctgg gtagcgcggc caatggccgt ggagcagccc      180

ctgtaaactg gctcgggcgc ccccacgccc gcccttcctt cttctcccag cattgccccc      240

cccacgtttc agcacagcgc tggccgcagt ctgacaggaa agggacggag ccaagatggc      300

ggcggccgac ggcgacgact cgctgtaccc catcgcggtg ctcatagacg aactccgcaa      360

tgaggacgtt cagcttcgcc tcaacagcat caagaagctg tccaccatcg ccttggccct      420

tggggttgaa aggacccgaa gtgagcttct gcctttcctt acagatacca tctatgatga      480

agatgaggtc ctcctggccc tggcagaaca gctgggaacc ttcactaccc tggtgggagg      540

cccagagtac gtgcactgcc tgctgccacc gctggagtcg ctggccacag tggaggagac      600

agtggtgcgg gacaaggcag tggagtcctt acgggccatc tcacacgagc actcgccctc      660

tgacctggag gcgcactttg tgccgctagt gaagcggctg gcgggcggcg actggttcac      720

ctcccgcacc tcggcctgcg gcctcttctc cgtctgctac ccccgagtgt ccagtgctgt      780

gaaggcggaa cttcgacagt acttccggaa cctgtgctca gatgacaccc ccatggtgcg      840

gcgggccgca gcctccaagc tgggggagtt tgccaaggtg ctggagctgg acaacgtcaa      900

gagtgagatc atccccatgt tctccaacct ggcctctgac gagcaggact cggtgcggct      960

gctggcggtg gaggcgtgcg tgaacatcgc ccagcttctg ccccaggagg atctggaggc     1020

cctggtgatg cccactctgc gccaggccgc tgaagacaag tcctggcgcg tccgctacat     1080

ggtggctgac aagttcacag agctccagaa agcagtgggg cctgagatca ccaagacaga     1140

cctggtccct gccttccaga acctgatgaa agactgtgag gccgaggtga gggccgcagc     1200

ctcccacaag gtcaaagagt tctgtgaaaa cctctcagct gactgtcggg agaatgtgat     1260

catgtcccag atcttgccct gcatcaagga gctggtgtcc gatgccaacc aacatgtcaa     1320

gtctgccctg gcctcagtca tcatgggtct ctctcccatc ttgggcaaag acaacaccat     1380

cgagcacctc ttgcccctct tcctggctca gctgaaggat gagtgccctg aggtacggct     1440

gaacatcatc tctaacctgg actgtgtgaa cgaggtgatt ggcatccggc agctgtccca     1500

gtccctgctc cctgccattg tggagctggc tgaggacgcc aagtggcggg tgcggctggc     1560

catcattgag tacatgcccc tcctggctgg acagctggga gtggagttct ttgatgagaa     1620

acttaactcc ttgtgcatgg cctggcttgt ggatcatgta tatgccatcc gcgaggcagc     1680

caccagcaac ctgaagaagc tagtggaaaa gtttgggaag gagtgggccc atgccacaat     1740

catccccaag gtcttggcca tgtccggaga ccccaactac ctgcaccgca tgactacgct     1800

cttctgcatc aatgtgctgt ctgaggtctg tgggcaggac atcaccacca agcacatgct     1860

acccacggtt ctgcgcatgg ctggggaccc ggttgccaat gtccgcttca atgtggccaa     1920

gtctctgcag aagatagggc ccatcctgga caacagcacc ttgcagagtg aagtcaagcc     1980

catcctagag aagctgaccc aggaccagga tgtggacgtc aaatactttg cccaggaggc     2040

tctgactgtt ctgtctctcg cctgatgctg gaagaggagc aaacactggc ctctggtgtc     2100

caccctccaa cccccacaag tccctctttg gggagacact ggggggcctt tggctgtcac     2160

tccctgtgca tggtctgacc ccaggcccct tcccccagca cggttcctcc tctccccagc     2220

ctgggaagat gtctcactgt ccacctccca acgggctagg ggagcacggg gttggacagg     2280

acagtgacct tgggaggaag gggctactcc gcccacgtca gggagagatg tgagcatccc     2340

gggtcactgg atcctgctgc tgtaatggga acccctcccc catttacttc tccacctccc     2400

gtcctcccca tcattggttt ttttttgtgt gtcaactgtg ccgtttttat tttattcctt     2460

ttattttccc ccttttcaca gagaaataaa ggtctagaag tagttggtca aaaaaaaaa      2519


<210>  1837
<211>  6259
<212>  DNA
<213>  homo sapiens

<400>  1837
cccttcctgc gccgcgctcg gctcccgcgc ctcgcctggc ctggccgctg ccgcgggcga       60

gcactgtgcg ctgggcagcc ccgggcccgc gcctcccgcc cagccggcgc ttcccggtcg      120

cagttcgctt tcccacccga gagccgcgag cgcccggccg aacccgcgat ggaataatgc      180

ccagcggccc gccaggtccc ggtcgttttc tgatgtgacg gctgagacat gagatcttca      240

gcctccaggc tctccagttt ttcgtcgaga gattcactat ggaatcggat gccggaccag      300

atctctgtct cggagttcat cgccgagacc accgaggact acaactcgcc caccacgtcc      360

agcttcacca cgcggctgca caactgcagg aacaccgtca cgctgctgga ggaggctcta      420

gaccaagata gaacagccct tcagaaagtg aagaagtctg taaaagcaat atataattct      480

ggtcaagatc atgtacaaaa tgaagaaaac tatgcacaag ttcttgataa gtttgggagt      540

aattttttaa gtcgagacaa ccccgacctt ggcaccgcgt ttgtcaagtt ttctactctt      600

acaaaggaac tgtccacact gctgaaaaat ctgctccagg gtttgagcca caatgtgatc      660

ttcaccttgg attctttgtt aaaaggagac ctaaagggag tcaaaggaga tctcaagaag      720

ccatttgaca aagcctggaa agattatgag acaaagttta caaaaattga gaaagagaaa      780

agagagcacg caaaacaaca tgggatgatc cgcacagaga taacaggagc tgagattgcg      840

gaagaaatgg agaaggaaag gcgcctcttt cagctccaaa tgtgtgaata tctcattaaa      900

gttaatgaaa tcaagaccaa aaagggtgtg gatctgctgc agaatcttat aaagtattac      960

catgcacagt gcaatttctt tcaagatggc ttgaaaacag ctgataagtt gaaacagtac     1020

attgaaaaac tggctgctga tttatataat ataaaacaga cccaggatga agaaaagaaa     1080

cagctaactg cactccgaga cttaataaaa tcctctcttc aactggatca gaaagaagat     1140

tctcagagcc ggcaaggagg atacagcatg catcagctcc agggcaataa ggaatatggc     1200

agtgaaaaga aggggtacct gctaaagaaa agtgacggga tccggaaagt atggcagagg     1260

aggaagtgtt cagtcaagaa tgggattctg accatctcac atgccacatc taacaggcaa     1320

ccagccaagt tgaaccttct cacctgccaa gtaaaaccta atgccgaaga caaaaaatct     1380

tttgacctga tatcacataa tagaacatat cactttcagg cagaagatga gcaggattat     1440

gtagcatgga tatcagtatt gacaaatagc aaagaagagg ccctaaccat ggccttccgt     1500

ggagagcaga gtgcgggaga gaacagcctg gaagacctga caaaagccat tattgaggat     1560

gtccagcggc tcccagggaa tgacatttgc tgcgattgtg gctcatcaga acccacctgg     1620

ctttcaacca acttgggtat tttgacctgt atagaatgtt ctggcatcca tagggaaatg     1680

ggggttcata tttctcgcat tcagtctttg gaactagaca aattaggaac ttctgaactc     1740

ttgctggcca agaatgtagg aaacaatagt tttaatgata ttatggaagc aaatttaccc     1800

agcccctcac caaaacccac cccttcaagt gatatgactg tacgaaaaga atatatcact     1860

gcaaagtatg tagatcatag gttttcaagg aagacctgtt caacttcatc agctaaacta     1920

aatgaattgc ttgaggccat caaatccagg gatttacttg cactaattca agtctatgca     1980

gaaggggtag agctaatgga accactgctg gaacctgggc aggagcttgg ggagacagcc     2040

cttcaccttg ccgtccgaac tgcagatcag acatctctcc atttggttga cttccttgta     2100

caaaactgtg ggaacctgga taagcagacg gccctgggaa acacagttct acactactgt     2160

agtatgtaca gtaaacctga gtgtttgaag cttttgctca ggagcaagcc cactgtggat     2220

atagttaacc aggctggaga aactgcccta gacatagcaa agagactaaa agctacccag     2280

tgtgaagatc tgctttccca ggctaaatct ggaaagttca atccacacgt ccacgtagaa     2340

tatgagtgga atcttcgaca ggaggagata gatgagagcg atgatgatct ggatgacaaa     2400

ccaagcccta tcaagaaaga gcgctcaccc agacctcaga gcttctgcca ctcctccagc     2460

atctcccccc aggacaagct ggcactgcca ggattcagca ctccaaggga caaacagcgg     2520

ctctcctatg gagccttcac caaccagatc ttcgtttcca caagcacaga ctcgcccaca     2580

tcaccaacca cggaggctcc ccctctgcct cctaggaacg ccgggaaagg tccaactggc     2640

ccaccttcaa cactccctct aagcacccag acctctagtg gcagctccac cctatccaag     2700

aagaggcctc ctcccccacc acccggacac aagagaaccc tatccgaccc tcccagccca     2760

ctacctcatg ggcccccaaa caaaggcgca gttccttggg gtaacgatgg gggtccatcc     2820

tcttcaagta agactacaaa caagtttgag ggactatccc agcagtcgag caccagttct     2880

gcaaagactg cccttggccc aagagttctt cctaaactac ctcagaaagt ggcactaagg     2940

aaaacagatc atctctccct agacaaagcc accatcccgc ccgaaatctt tcagaaatca     3000

tcacagttgg cagagttgcc acaaaagcca ccacctggag acctgccccc aaagcccaca     3060

gaactggccc ccaagcccca aattggagat ttgccgccta agccaggaga actgcccccc     3120

aaaccacagc tgggggacct gccacccaaa ccccaactct cagacttacc tcccaaacca     3180

cagatgaagg acctgccccc caaaccacag ctgggagacc tgctagcaaa atcccagact     3240

ggagatgtct cacccaaggc tcagcaaccc tctgaggtca cactgaagtc acacccattg     3300

gatctatccc caaatgtgca gtccagagac gccatccaaa agcaagcatc tgaagactcc     3360

aacgacctca cgcctactct gccagagacg cccgtaccac tgcccagaaa aatcaatacg     3420

gggaaaaata aagtgaggcg agtgaagacc atttatgact gccaggcaga caacgatgac     3480

gagctcacat tcatcgaggg agaagtgatt atcgtcacag gggaagagga ccaggagtgg     3540

tggattggcc acatcgaagg acagcctgaa aggaaggggg tctttccagt gtcctttgtt     3600

catatcctgt ctgactagca aaacgcagaa ccttaagatt gtccacatcc ttcatgcaag     3660

actgctgcct tcatgtaacc ctgggcacag tgtgtatata gctgctgtta cagagtaaga     3720

aactcatgga agggccacct caggaggggg atataatgtg tgttgtaaat atcctgtggt     3780

tttctgcctt caccagtatg agggtagcct cggacccggc gcgccttact ggtttgccaa     3840

agccatcctt ggcatctagc acttacatct ctctatgctg ttctacaagc aaacaaacaa     3900

aaataggagt ataggaactg ctggctttgc aaatagaagt ggtctccagc aaccgttgaa     3960

aggcatagaa ttgactctgt tcctaacaat gcagtattct caattgtgtt actgaaaatg     4020

caacattagc aaagaggtgg gttctgtttt ccaggtgaaa cttttagctc catgacagac     4080

cagcctgtag ttatctgtgt acacagttta cagctacaaa aacctacttt ggtatttatt     4140

acagaaaagt gctcagttaa atgtaagtgt tattccttca gcaaaatatt cactgaccca     4200

aaactcttta tggcatttta caatgcacac agcctcatgc aagtttagac aagtggattt     4260

atactgtctt atgagtgccc gcccctgata tattacctca ttatgcaaaa ataacatatc     4320

tttcatgact attttgacaa aagtttaaaa cacatatgaa gttcaaattt caggaaccaa     4380

ggactgccag aaaatattag cctctacatt acgcatgcat ttagaagctt acctgaaatc     4440

tgccttttat aaaggaatag tatggataag tggaattgta cattttttaa acttgattgc     4500

cattaaagca gaaattataa ggttgcaaca atatttgttt ctaatcactg gctttctcaa     4560

gagtatggat tgacatattg tgttatgaat gcacatctct cagatgtgtt gaagcatcca     4620

ttgcatccat tttttattat tttcttagtt ttgttcttgg acaaatttaa acttttaaaa     4680

gattattcaa gatgaattta aaagtcaacc cttcacacag tttccctact gtatgtagaa     4740

tccaggtgct gaaaccaagt gtttcttttc ccatgctctt tgttaaaccc caattataga     4800

taatttttcc agtcttaagc tctgtccacc ttcaagtcaa ttcataacca agtttttgaa     4860

cgctgctatg aattgcactg tgaaaagcac tcttccctct cagttttctt ttcatcccag     4920

ccatgtttat cagatcctta agaacattgt atttcagtct tttacatcag tctgaatttt     4980

ggaaaagaat gcaatagttg tactccacag tcagtggaac tgttccctga gtccgaggct     5040

catgtgtcat tctggcacta catttgctta aattgctatt ttggcaacag cacagaaaac     5100

taatattttt aagcagagaa tcttggcaat gagtgagaga tgttaatttc acagaagcac     5160

aactcccaac ccaaccctta ggaaaagccc tcttccatcg ttacagtgct cagtgaatat     5220

taatttagtt ctgcttaagt ggttgctata caaactttga atagccacct aataaataaa     5280

ccttgcatga caaacctgca aaatatttta tcagctgtta ttggaaagtg attttaagca     5340

attgcttcct cagtgtcagg gcacatgtga atttccacac caaacagagc atgaggaacc     5400

agttgacatg ctgggttgtg actggcagct ttagcagcct cggtactgaa gccacaccag     5460

tgtccggatg gaagtctgca tctgaggttg ctcagtgtcc cggtcattca tttacacatt     5520

ttaacttgca ttaaagagct gttcttttct gtggcctaga ctcttttcac tgatctcaaa     5580

ataaactggt ttttttcaaa aaaaaaaaaa aaacaaaaac aaaaaaaaaa cacaaaagct     5640

gcatgtctaa aattacatgg agttagtgtc tattcttttt ccccttttgc agcaacttac     5700

acagcatttt taacaccttt tttttctagt ttttttgttc ggttttgttt tccatcagga     5760

atttgagttc tctctaaccc agcttactgt gggacatagg aaaactcagt agaaatacct     5820

ttggtgatct tgttgagttt aagtctgatc ttgatcttaa actcagtaag ccactatctg     5880

caattttgta cattatatag tattttgaag atatggaacc ttatgaaaaa aaaatagcaa     5940

attagttctt tttcccccag aggggaaagt tatgttctgc aaatagtgtg tgtcttattt     6000

tactgttgaa cagcaattgc tatttatttt tttattgcct agaacttcaa catgttgtat     6060

aggaatcctg tagtgccact agttaaatgc cgaattctca tctggatgtt accatcaaac     6120

atcagtacac ttgtcatttc acatgtgttt aatgtgacag tttttcagta ctgtatgtgt     6180

taatttctac tttttttaat atttaaaatt gcttttaaat aaacatattc tcagttgatc     6240

ccaaaaaaaa aaaaaaaaa                                                  6259


<210>  1838
<211>  3591
<212>  DNA
<213>  homo sapiens

<400>  1838
actactccct ctgcagtctc gcctgccgac ttccttctgc gcgcctcgta aaaccgggga       60

agttcaatca ttccgcagcg agccgcggcg gccgcactgg gcatgctcag tctccgggct      120

ccgctcggca ggcgagaggc gtcctccggc tctgggctcc ggtcggtggg tgcctcggct      180

cggctttccc cggcgctggc tgggctcagc ggcccctgag cccaagcgac acacgccccg      240

cggtccccga tccggcccct gggagagccg cgccgttctg gaacccggga gcccccaact      300

tcgcgccaag ttcggagccg ccttctgagg gagacatgaa aaagatgagc aggaatgttt      360

tgctacaaat ggaggaggag gaggacgacg acgatgggga tatcgtgttg gaaaaccttg      420

gacagacaat tgtccccgat ttgggatcac tggaaagtca gcatgatttt cgaaccccgg      480

agtttgaaga atttaatgga aaacctgact ccctcttttt taatgatggc cagcgaagaa      540

ttgactttgt tctagtatat gaggatgaaa gcagaaaaga gaccaataaa aagggtacaa      600

atgaaaaaca aaggaggaaa agacaagcat acgaatctaa ccttatctgt catggcctgc      660

agttagaagc aacaagatca gtattggatg acaagcttgt atttgtaaaa gtacacgcac      720

catgggaggt gttatgtacg tatgctgaga taatgcacat caaattgcct ctgaaaccca      780

atgatctgaa aaaccggtcc tcagcctttg gtacactcaa ctggtttacc aaagtcctca      840

gtgtagacga aagcatcatc aagccagagc aagagttttt cactgcccca tttgagaaga      900

accggatgaa tgatttttac atagttgata gagatgcttt cttcaatcca gccaccagaa      960

gccgcattgt ttacttcatc ctctctcggg tcaagtatca agtgataaac aatgttagca     1020

agtttgggat caacagactt gtaaactctg ggatctacaa ggcagctttc ccactccatg     1080

attgcaaatt ccgccgtcag tcagaggatc ccagctgccc taatgaacgg taccttctgt     1140

acagagaatg ggctcatcct cgaagcatat acaaaaagca gcccttggat cttatcagga     1200

aatactatgg agagaagatt ggaatctact ttgcttggct gggctattac actcagatgc     1260

ttctcctggc cgcagttgta ggagtggctt gctttctcta tggatatctt aatcaagata     1320

actgtacatg gagcaaagaa gtttgtcatc ctgatattgg tggcaagatc ataatgtgtc     1380

ctcagtgtga taggctttgt ccattctgga aactcaatat tacttgcgag tcctcaaaga     1440

aattgtgcat cttcgacagt tttggaaccc tggtctttgc agtatttatg ggagtatggg     1500

ttaccttgtt tttggagttt tggaagcgac gccaggcaga acttgagtat gaatgggata     1560

ctgttgagtt acagcaggaa gaacaagccc gaccagaata cgaagcacga tgtactcacg     1620

tagtgataaa tgagattact caggaagaag aacgcattcc ctttactgcc tggggaaaat     1680

gtatacggat aaccctctgt gccagtgctg tctttttctg gatcctattg atcatcgctt     1740

cagttattgg gatcattgtc tataggctct cggtgttcat tgtattttct gcaaaacttc     1800

ccaagaacat taatggaaca gacccaatcc agaaatacct gactccacag acagccacgt     1860

ccatcacggc ctccatcatc agctttataa ttatcatgat tctgaacacc atatatgaaa     1920

aagtggcaat tatgattact aacttcgaac tcccaaggac ccagactgat tatgagaaca     1980

gcctcaccat gaagatgttc ttattccagt ttgtcaacta ctactcttca tgcttctaca     2040

tagcattctt taagggcaaa tttgtaggct atccaggaga cccagtttat tggttgggaa     2100

aatacagaaa tgaagagtgt gacccaggtg gctgtcttct tgaactgaca actcagctga     2160

caataatcat gggaggaaaa gcaatctgga ataacataca agaagtatta ttgccctgga     2220

tcatgaatct aattgggcga tttcacagag tttctggatc agaaaagata accccacgat     2280

gggaacagga ctaccatctg cagcctatgg gcaaactggg attattttat gaatatcttg     2340

aaatgattat tcagtttggg ttcgtcacct tatttgtggc ctcttttcca ctggcccctc     2400

tgttggctct cgtgaacaat atattggaaa taagagtgga cgcatggaaa ctgaccaccc     2460

agtttagacg cctggtacca gagaaagccc aagacattgg agcatggcag cccatcatgc     2520

aaggaatagc aattctggct gtggtgacca atgccatgat catagctttc acgtcggaca     2580

tgatcccccg cctagtgtac tactggtcct tctccgtccc tccctacggg gaccacactt     2640

cctacaccat ggaagggtac atcaacaaca ctctctccat cttcaaagtc gcagacttca     2700

aaaacaaaag caagggaaac ccgtactctg acctgggtaa ccataccaca tgcaggtatc     2760

gtgatttccg atacccacct ggacaccccc aggagtataa acacaacatc tactattggc     2820

atgtgattgc agccaagctg gcttttatca ttgtcatgga gtatctcgct ttgttgccca     2880

ggctgggaca cagtggcatg atcttggctc actgcaacct ccgcctccca gttgactgct     2940

gtatgtgtta taggtttgtc gatgaaatta gacttttgga acaactaact tctgacttta     3000

ttgactccct ctattatata ttttctattt caataatatc tattttcttt tctgttactt     3060

tctttttcct tctactttct ttggggccaa ctccgtgttt ttctgtatcg aatttcttaa     3120

gttagattta ttcaataatt cattcaacaa atatttgtgt gtctattatg tggccagcat     3180

tgtttcatgt gctcaagata gagtagcatt gtttggctca ttaatattcc aatactggca     3240

tttaagacca ttaattttcc tctaaatcgt atttgagctg caacccacaa gcttttatat     3300

gtatagtttt ttgttgttgc tattattaaa agtattttag atcctccctt gttttgcttt     3360

tcaatctgaa atgccttcat gccattttaa tttttaaaag gtaatttaat tgagcctaat     3420

ttctttttct tttttctttt ttttgagaca gagtcttact ctgtcaccca ggctggagtg     3480

cagtggcgtg atctcagctc aatgcaagct ctgcctccca ggttcacgcc attctcctgt     3540

ctcagcctcc caagtagctg ggactacagg cgcccaccac catgcctggc t              3591


<210>  1839
<211>  5910
<212>  DNA
<213>  homo sapiens

<400>  1839
agctccagcc gcactgcccc gatggctccc tacccctgtg gctgccacat cctgctgctg       60

ctcttctgct gcctggcggc tgcccgggcc aacctgctga acctgaactg gctttggttc      120

aataatgagg acaccagcca tgcagctacc acgatccctg agccccaggg gcccctgcct      180

gtgcagccca cagcagatac caccacacac gtgacccccc ggaatggttc cacagagcca      240

gcgacagccc ctggcagccc tgagccaccc tcagagctgc tggaagatgg ccaggacacc      300

cccacttctg ccgagagccc ggacgcgcca gaggagaaca ttgccggtgt cggagccgag      360

atcctgaacg tggccaaagg catccggagc ttcgtccagc tgtggaatga cactgtcccc      420

actgagagct tggccagggc ggaaaccctg gtcctggaga ctcctgtggg cccccttgcc      480

ctcgctgggc cttccagcac cccccaggag aatgggacca ctctctggcc cagccgtggc      540

attcctagct ctccgggcgc ccacacaacc gaggctggca ccttgcctgc acccacccca      600

tcgcctccct ccctgggcag gccctgggca ccactcacgg ggccctcagt gccaccacca      660

tcttcagagc gcatcagcga ggaggtgggg ctgctgcagc tccttgggga ccccccgccc      720

cagcaggtca cccagacgga tgaccccgac gtcgggctgg cctacgtctt tgggccagat      780

gccaacagtg gccaagtggc ccggtaccac ttccccagcc tcttcttccg tgacttctca      840

ctgctgttcc acatccggcc agccacagag ggcccagggg tgctgttcgc catcacggac      900

tcggcgcagg ccatggtctt gctgggcgtg aagctctctg gggtgcagga cgggcaccag      960

gacatctccc tgctctacac agaaccaggt gcaggccaga cccacacagc cgccagcttc     1020

cggctccccg ccttcgtcgg ccagtggaca cacttagccc tcagtgtggc aggtggcttt     1080

gtggccctct acgtggactg tgaggagttc cagagaatgc cgcttgctcg gtcctcacgg     1140

ggcctggagc tggagcctgg cgccgggctc ttcgtggctc aggcgggggg agcggaccct     1200

gacaagttcc agggggtgat cgctgagctg aaggtgcgca gggaccccca ggtgagcccc     1260

atgcactgcc tggacgagga aggcgatgac tcagatgggg catccggaga ctctggcagc     1320

gggctcgggg acgcccggga gcttctcagg gaggagacgg gcgcggccct aaaacccagg     1380

ctccccgcgc caccccccgt caccacgcca cccttggctg gaggcagcag cacggaagat     1440

tccagaagtg aagaagtcga ggagcagacc acggtggctt cgttaggagc tcagacactt     1500

cctggctcag attctgtctc cacgtgggac gggagtgtcc ggacccctgg gggccgcgtg     1560

aaagagggcg gcctgaaggg gcagaaaggg gagccaggtg ttccgggccc acctggccgg     1620

gcaggccccc caggatcccc atgcctacct ggtcccccgg gtctcccgtg cccagtgagt     1680

cccctgggtc ctgcaggccc agcgttgcaa actgtccccg gaccacaagg acccccaggg     1740

cctccgggga gggacggcac ccctggaagg gacggcgagc cgggcgaccc cggtgaagac     1800

ggaaagccgg gcgacaccgg gccacaaggc ttccccggga ctccagggga cgtaggtccc     1860

aagggcgaca agggagaccc tggggttgga gagagagggc ccccaggacc ccaagggcct     1920

ccagggcccc caggaccctc cttcagacac gacaagctga ccttcattga catggaggga     1980

tctggcttcg ggggcgatct ggaggccctg cggggtcctc gaggcttccc tggacctccc     2040

ggaccccccg gtgtcccagg cctgcccggc gagccaggcc gctttggggt gaacagctcc     2100

gacgtcccag gacccgccgg ccttcctggt gtgcctgggc gcgagggtcc ccccgggttt     2160

cctggcctcc cgggaccccc aggccctccg ggaagagagg ggcccccagg aaggactggg     2220

cagaaaggca gcctgggtga agcaggcgcc ccaggacata aggggagcaa gggagccccc     2280

ggtcctgctg gtgctcgtgg ggagagcggc ctggcaggag cccccggacc tgctggacca     2340

ccaggccccc ctgggccccc tgggccccca ggaccaggac tccccgctgg atttgatgac     2400

atggaaggct ccggggggcc cttctggtca acagcccgaa gcgctgatgg gccacaggga     2460

cctcccggcc tgccgggact taagggggat cctggcgtgc ctgggctgcc gggggcgaag     2520

ggagaagttg gagcagatgg agtccccggg ttccccggcc tccctggcag agagggcatt     2580

gctgggcccc aggggccaaa gggagacaga ggcagccggg gagaaaaggg agatccaggg     2640

aaggacggag tcgggcagcc gggcctccct ggcccccccg gacccccggg acctgtggtc     2700

tacgtgtcgg agcaggacgg atccgtcctg agcgtgccgg gacctgaggg ccggccgggt     2760

ttcgcaggct ttcccggacc tgcaggaccc aagggcaacc tgggctctaa gggcgaacga     2820

ggctccccgg gacccaaggg tgagaagggt gaaccgggca gcatcttcag ccccgacggc     2880

ggtgccctgg gccctgccca gaaaggagcc aagggagagc cgggcttccg aggacccccg     2940

ggtccatacg gacggccggg gtacaaggga gagattggct ttcctggacg gccgggtcgc     3000

cccgggatga acggattgaa aggagagaaa ggggagccgg gagatgccag ccttggattt     3060

ggcatgaggg gaatgcccgg ccccccagga cctccagggc ccccaggccc tccagggact     3120

cctgtttacg acagcaatgt gtttgctgag tccagccgcc ccgggcctcc aggattgcca     3180

gggaatcagg gccctccagg acccaagggc gccaaaggag aagtgggccc ccccggacca     3240

ccagggcagt ttccgtttga ctttcttcag ttggaggctg aaatgaaggg ggagaaggga     3300

gaccgaggtg atgcaggaca gaaaggcgaa aggggggagc ccgggggcgg cggtttcttc     3360

ggctccagcc tgcccggccc ccccggcccc ccaggcccac gtggctaccc tgggattcca     3420

ggtcccaagg gagagagcat ccggggccag cccggcccac ctggacctca gggacccccc     3480

ggcatcggct acgaggggcg ccagggccct cccggccccc caggcccccc agggccccct     3540

tcatttcctg gccctcacag gcagactatc agcgttcccg gccctccggg cccccctggg     3600

ccccctgggc cccctggaac catgggcgcc tcctcagggg tgaggctctg ggctacacgc     3660

caggccatgc tgggccaggt gcacgaggtt cccgagggct ggctcatctt cgtggccgag     3720

caggaggagc tctacgtccg cgtgcagaac gggttccgga aggtccagct ggaggcccgg     3780

acaccactcc cacgagggac ggacaatgaa gtggccgcct tgcagccccc cgtggtgcag     3840

ctgcacgaca gcaaccccta cccgcggcgg gagcaccccc accccaccgc gcggccctgg     3900

cgggcagatg acatcctggc cagcccccct cgcctgcccg agccccagcc ctaccccgga     3960

gccccgcacc acagctccta cgtgcacctg cggccggcgc gacccacaag cccacccgcc     4020

cacagccacc gcgacttcca gccggtgctc cacctggttg cgctcaacag ccccctgtca     4080

ggcggcatgc ggggcatccg cggggccgac ttccagtgct tccagcaggc gcgggccgtg     4140

gggctggcgg gcaccttccg cgccttcctg tcctcgcgcc tgcaggacct gtacagcatc     4200

gtgcgccgtg ccgaccgcgc agccgtgccc atcgtcaacc tcaaggacga gctgctgttt     4260

cccagctggg aggctctgtt ctcaggctct gagggtccgc tgaagcccgg ggcacgcatc     4320

ttctcctttg acggcaagga cgtcctgagg caccccacct ggccccagaa gagcgtgtgg     4380

catggctcgg accccaacgg gcgcaggctg accgagagct actgtgagac gtggcggacg     4440

gaggctccct cggccacggg ccaggcctcc tcgctgctgg ggggcaggct cctggggcag     4500

agtgccgcga gctgccatca cgcctacatc gtgctctgca ttgagaacag cttcatgact     4560

gcctccaagt agccaccgcc tggatgcgga tggccggaga ggaccggcgg ctcggaggaa     4620

gcccccaccg tgggcaggga gcggccggcc agcccctggc cccaggacct ggctgccata     4680

ctttcctgta tagttcacgt ttcatgtaat cctcaagaaa taaaaggaag ccaaagagtg     4740

tattttttta aaagtttaaa acagaagcct gatgctgaca ttcacctgcc ccaactctcc     4800

cctgacctgt gagcccagct gggtcaggca gggtgcagta tcatgccctg tgcaacctct     4860

tggcctgatc agaccacggc tcgatttctc caggatttcc tgctttggga agccgtgctc     4920

gccccagcag gtgctgactt catctcccac ctagcagcac cgttctgtgc acaaaaccca     4980

gacctgttag cagacaggcc ccgtgaggca atgggagctg aggccacact cagcacaagg     5040

ccatctgggc tcctccaggg tgtgtgctcg ccctgcggta gatgggaggg aggctcaggt     5100

ccctggggct agggggagcc ccttctgctc agctctgggc cattctccac agcaacccca     5160

ggctgaagca ggttcccaag ctcagaggcg cactgtgacc cccagctccg gcctgtcctc     5220

caacaccaag cacagcagcc tggggctggc ctcccaaatg agccatgaga tgatacatcc     5280

aaagcagaca gctccaccct ggccgagtcc aagctgggag attcaaggga cccatgagtt     5340

ggggtctggc agcctcccat ccagggcccc catctcatgc ccctggctgg gacgtggctc     5400

agccagcact tgtccagctg agcgccagga tggaacacgg ccacatcaaa gaggctgagg     5460

ctggcacagg acatgcggta gccagcacac agggcagtga gggagggctg tcatctgtgc     5520

actgcccatg gacaggctgg ctccagatgc agggcagtca ttggctgtct cctaggaaac     5580

ccatatcctt accctccttg ggactgaagg ggaaccccgg ggtgcccaca ggccgccctg     5640

cgggtgaaca aagcagccac gaggtgcaac aaggtcctct gtcagtcaca gccacccctg     5700

agatccggca acatcaaccc gagtcattcg ttctgtggag ggacaagtgg actcagggca     5760

gcgccaggct gaccacagca cagccaacac gcacctgcct caggactgcg acgaaaccgg     5820

tggggctggt tctgtaattg tgtgtgatgt gaagccaatt cagacaggca aataaaagtg     5880

accttttaca ctgaaaaaaa aaaaaaaaaa                                      5910


<210>  1840
<211>  4715
<212>  DNA
<213>  homo sapiens

<400>  1840
aggatcaagg gaatcgtggc tgcctgcccc actgagccca ctgccccaac cccctctcct       60

tcttgtgcca gatcccttgg gattggagcc gctgtgagca gtggctaggc atttgagcac      120

ctctgtctct gccttgctcc atagcagctg ctgtgctgaa caccgctctt ccggcaccgg      180

tacaagctgc cgcaccagta caggcctcct cgacggccca accccggcca ccagcccagc      240

cccagacgct gttccagacc cagccgctgc tgcagaccac acctgccatc ctcccgcagc      300

ccactgctgc caccgctgct gcccctaccc ccaagccagt ggacaccccc ccacagatca      360

ccgtccagcc tgcaggcttc gcatttagcc caggaatcat cagtgctgct tccctcgggg      420

gacagaccca gatcctgggg tccctcacta cagctccagt cattaccagc gccattccca      480

gcatgccagg gatcagcagt cagatcctca ccaatgctca gggacaggtt attggaaccc      540

ttccatgggt agtgaactca gctagtgtgg cggccccagc accagcccaa agcctgcagg      600

tccaggccgt gaccccccag ctgttgttga acgcccaggg ccaggtgatt gcgaccctgg      660

ctagcagccc cctgcctcca cctgtggctg tccggaagcc aagcacacct gagtcccctg      720

ctaagagtga ggtgcagccc atccagccca caccaaccgt gccccagcct gctgtggtca      780

ttgccagccc agctccagcc gccaagccat ctgcctctgc tcctatccca attacctgct      840

cagagacccc caccgtcagc cagttggtgt ccaagccaca tactccaagt ctggatgagg      900

atgggatcaa cttagaagag atccgggagt ttgccaagaa ctttaagatc cggcggctct      960

cgctgggcct tacacagacc caggtgggtc aggctctgac tgcaacggaa ggtccagcct     1020

acagccagtc agccatctgc cggttcgaga agctagacat cacacccaag agtgcccaga     1080

agctaaagcc ggtgctggaa aagtggctaa acgaagctga actgcggaac caggaaggcc     1140

agcagaacct gatggagttt gtgggaggcg agccctccaa gaaacgcaaa cgccgcacct     1200

ccttcacccc ccaggccata gaggctctca atgcctattt tgagaagaac ccactgccca     1260

caggccagga gatcactgaa attgctaagg agctcaacta cgaccgtgag gtagtgcggg     1320

tctggttctg caatcggcgc cagacgctca agaacaccag caagctgaac gtctttcaga     1380

tcccttaggg ctcagcccct ggccctgtgt tctagcactt tgtccatttc ccgtggcatc     1440

cggctgcagc cactgccatg acagcacctg tcattttgcc acgtgcagct gtgctcaccc     1500

caggtcatca gactccaccg tgtgcatgtg catcaatgtc cctcttttct cccacacatc     1560

tcacatcatg gggaggccag agggggccac acgagagctc caggctctgg gctggtcact     1620

ccgaagaaga ggatttgtga cgtcacttag agaagcacct tgctagcatg gtttctgaag     1680

ggtgaattct ggtggggaac cagaaactcc ctgtctttgg ggcagggcta aagcagctcc     1740

taaggaccac tggccattag ctcttgcttt tgatggcatt ctctttccac cttgtcttct     1800

cctttgctcc tctgtgttag tgtggcaggt atgacaactc atccagtgga aacacagcct     1860

cacactgccc ttccgccccc cacactttgc ctgcaggtgc accgaaagga cctgggagat     1920

aaaattcaaa aaagtgtgat gtgctgctca gaaggtcaga ctccatgtct gccttgacct     1980

caaggtcaga aggttcccaa acccctgggg ctggaacatg ggatctcctc ttccacctct     2040

tcctggttcc tttgcgggga aaattgcact aaaacagaac cttttcttaa tccatgttgg     2100

aaggaagcaa cagtgaactc tacctgttct ggagttctcc tgggtctgca gaaggttggg     2160

aatttagaaa ataaggctgt tctttcatat tttaatttaa tctctgtcaa tggccatccc     2220

tcccacaaaa aaacgtgggt taagagaact tgcagactgg atatgcaagc aaacgggcaa     2280

ctctggagaa aaataaggaa aggaatgctg actttctctt tctttctctt gtccccacac     2340

ccattcccaa cccaatactg gggccttctc aaaaggagca aattaaacaa taaaccagac     2400

agcaaggccc tgggggaaag gacaacatcc tgaaataaat gatggagccc aggaaggtct     2460

cttgtggaag ttgacttaac tctaattttc tttgtaactt taagccttgg atacgggagg     2520

agaaatctca ttttgtcgag tctcagacca tgtctgtgtg taagcaatcc ccacagtgtc     2580

ctctgagcca aggacacccc cagatcagat tgagttttgc ttctagacgg ggtagctatg     2640

gtaccttggg ggttagctct catccaagct gttaagtgag tttccagcct cactgtggct     2700

ggaaagcccc taaaattcag tatgtaactc caggaagtca ggagagaact gagatttgcc     2760

tagatgacca caggcttgcg gtgtagatta tccctaaagg gccccaagtc acgggggtca     2820

accacccctg tcttcagtac tcttatcctt acagaggctg gtctctaaca gctgcctcca     2880

gtggacctcc catgatccac cctgagggaa ggaccgtcag ctggggacac atcaccacct     2940

ctgtcagtca ctggtgcaga gccacctcct agcctagctt cctctggtgt cctgtttcct     3000

ttcccactta ctgttggtgc ctcccaggcc ctgcagtgcc agcgtggcca ccctcttggt     3060

agcctggcca gtaagaggag gacagttgtg tgctgaatta gcacacgcac gtgcagcgcg     3120

cacagacgcg cgcacacaca cacacataca cgctctgctg catttggaca aaccatgcct     3180

gccagagtgt agcagaggtg aggaagcagg tgggcagctt gcctgaccca gcttttcagg     3240

agagcgtgtc tccaacagag agtctccaca ctctagttca gggttatcga cctgcctcaa     3300

tgagatgaca gactcatttg ggaggggtgt tgcaaacaag ttttcagtga gaatagttaa     3360

gttccagagc ttgtaaagga ttcagtgact gacacttcag taaattaggc caggcacatt     3420

ggcttatgcc tgtaattcca acactttgga aggccgaggt gggcggatca tttgaggtct     3480

ggagttcgag accagcctga ccaacatggt gaaaccccgt ctctactaaa aatacaaaaa     3540

ttagccaggt gtggtagtgc acatctgtaa tcccagctac ttgggaggtg gaggcaggag     3600

aattgcttga accctggagg ttgcaatgag ctgagatcac actacttcac tccagcctgg     3660

gtgacagagc aagactcggt ctcaaacaaa caaaaactta tggcgatgca ggttttcatg     3720

ctcagacgct tgcattcagg tatgctttct tttttgagag agacaaatgg gtcacagctg     3780

gcaccctggg aatagcacat aatccagggt gtgtctgtgg tggtggacgt gcaggggaac     3840

accatctgtc ctgtgtcatg atgggaaaac aatcatgaac cactggtcta aattaggcct     3900

ggccatgctt tctcagcccc tccctcattt aaatttgtct tcccaaagct gagctaaaac     3960

taaaccattt ctcctctgct ggaatgatgg attggtcatt cagaggaaca ataccagggg     4020

tgggaggttt gcaggctgag ttccccaggc atgggggtgc agggtgtccc tgaggtttac     4080

ccaaagcaca gctcgctggc ctgtgacctc tgcccttcct cccacagtgt aagacccccc     4140

aggaagcagc tggggcctga acctctcacc taggaggtag gtttatttta ttttttgtta     4200

gcatcaggct ctgaaggagt tggtatacat tttgttttga aaacatcttc tggacttaca     4260

ccagagctta gtgtcgtctt tactatggaa agagaggaga atggacagaa atggtttaac     4320

tgtgtggagt tttgtttgtt ttgttttaaa tggaagaaag accaaaactt tcctggtgga     4380

tcagctaggg cctttgaccc tgcattacca cggcatttta tccaggtgaa gtccagggaa     4440

agaactcagc caaatggact aaggaacaca cgagtttgga atgcgagact ctgacatttt     4500

tgtgttcttg gaaatccaat taccttccca tgcccagatt tccttcctgc ctcttggacc     4560

aggctctggc actgaggttc tcactgttcc caacacagac aaagcttcct gagggctgga     4620

ggggcagcaa ggggagagga gaatggggaa gaagcgcttg atgtagttgt gtggaataaa     4680

cagtattttt tcttttgtaa aaaaaaaaaa aaaaa                                4715


<210>  1841
<211>  4299
<212>  DNA
<213>  homo sapiens

<400>  1841
acgtaccagg gctcattgcg tgacggttac acttccggcg ggctacgtgc gcgcggcgag       60

cgccgggcgt acttttgcgt ggttgctcca ccccctcagc cttgccttcg ccgccgttgg      120

ggctggaagt tcccgccagg tccgtgccgg gcgagagaga tgctgcccgg cccgcctcgg      180

ctttgaggcg agagaagtgt cccagaccca tttcgccttg ctgacggcgt cgagccctgg      240

ccagacatgt ccacagggtt ctccttcggg tccgggactc tgggctccac caccgtggcc      300

gccggcggga ccagcacagg cggcgttttc tccttcggaa cgggagcgtc tagcaaccct      360

tctgtggggc tcaattttgg aaatcttgga agtacttcaa ctccagcaac tacatctgct      420

ccttcaagtg gttttggaac cgggctcttt ggatctaaac ctgccactgg gttcactcta      480

ggaggaacaa atacaggaac gccagccact acatctgcag ctacaacagg cttcagttta      540

ggattcaata aacctgcagc atctgccaca ccatttgctc tacctattac ctctacctca      600

gctagcggtc tgactctttc gtctgctctg acatcaactc cagcagcatc cacaggattt      660

actctaaata atttgggtgg gacaacagcc acaactacaa ctgcatcaac aggcctctct      720

ttagggggag ccttagctgg tttgggaggt tcacttttcc agagtacaaa cacaggaaca      780

tcaggacttg gacagaatgc tttagggttg actttgggaa ctacagcagc tacttcaact      840

gcaggcaatg aaggccttgg tggtatagat ttcagtagct cctcagataa aaagagtgat      900

aaaacgggaa caagaccaga ggatagtaaa gctctgaagg atgaaaatct acctcctgtc      960

atctgccagg atgttgaaaa tctccagaaa tttgtgaagg agcagaaaca agttcaagaa     1020

gaaattagta gaatgtcttc aaaagcaatg cttaaggtac aagaagatat taaagctctg     1080

aagcagctcc tgtcgttggc tgccaatgga atacagagaa acactctcaa cattgacaaa     1140

ttgaaaatag aaactgctca ggagttgaag aatgctgaaa tagctttaag aacccagaag     1200

acaccacctg gacttcaaca tgaatatgca gctcctgctg actacttcag aatcttggtt     1260

cagcaatttg aggtacagct tcagcagtac aggcagcaga ttgaagaact agaaaaccat     1320

cttgccactc aagcaaataa ttcacatata acccctcaag atttgtcaat ggctatgcag     1380

aaaatttatc aaacatttgt agctttagcg gcacaacttc agtctattca tgaaaatgta     1440

aaggttctga aagaacagta ccttggctac aggaaaatgt tcttgggaga tgctgttgat     1500

gtgtttgaaa caaggcgagc agaagccaag aagtggcaga acacacccag agttactact     1560

ggacccactc ctttcagcac catgccaaac gcagcagccg ttgccatggc tgcaacactt     1620

acacagcagc aacagcctgc tacagggcca cagccatctc tgggagttag ttttggaacg     1680

ccattcggct caggtattgg cactggcttg caatcaagtg gcttaggttc ttcaaacctt     1740

ggaggatttg gaactagctc tggttttgga tgcagcacca caggggcctc cacatttgga     1800

tttggaacaa caaataaacc ctcaggaagt cttagtgcag gctttggcag ctcaagtaca     1860

tctgggttta acttcagcaa tcctggcatc acggcatcag ctggtttgac ttttggggtg     1920

tccaatcctg cctctgcagg ttttggaaca ggaggacaac tccttcagtt gaagaaacct     1980

ccagctggaa acaaaagagg aaaaagataa acatgggttg atgtgttgag agaatccata     2040

gcagcaccgt tcattctatg agtctatttt tctaatgatg cagtaattaa attgcatccc     2100

aggagattta taaagttttg atatttttcc ctactctgga atttgaactt tcttcatgtt     2160

tgccatactg aacatctttt ttcttgtgga atttaaagtc cagctgtgtt ttctttttaa     2220

tttgattctc agtgtaagaa atgttctgat tacatcactg attggtaatg gttagaaacc     2280

attaacctaa aacttactat ttaacctagt gtttttgttg atgaggttta cattatgtga     2340

atacatgcac atttgtttct tatacaggtg gtgtgaactc tagggcctat actagaatca     2400

atttgttcct tgttaaaggc cttttgaatt atactgcagg gcatcttgtg aatatgtatg     2460

taaatatata cagaataata cacacagttg tgtgtgcata taaaatacat atttacgcca     2520

ggcgtggtgg ctcacgcctg taatcccagc actttgggag gccgaggcag gcggatcacc     2580

tgaggtcagg agtttgagac cagcctgaca tggtgaaacc ccatctctac gaaaaataca     2640

aaaattagct gggcatagtg gcgggtacct ataatcccag ctactcggga ggctgaggca     2700

cgagaatcac ttgaagccgg gaggtggggg ttgcagtgag ccgagatcac accactgcac     2760

tccagcctgg gcaacaagag caaaactccg tctcaaaaaa gatgaaaata aaataaaata     2820

tatatttaca ggcctacaac ttttgcctca gactgttccc cttttctaag ggtattcaag     2880

ttttcacctt ttaagcttca tatcctcagt gcttgtagaa tgatgagctt agaggtacca     2940

ggtcattgca gttgtttgct taaagactta ttgaaatggt tactggcgta aatacttggc     3000

caactcaact ttattgcccc tgatcttttc catttttgtt tccaccttaa cctatagcag     3060

ctcctccaaa tgaggaatgc tgtaagtaag actcatcaaa cagattttaa ccattttatt     3120

atcctgtgtg tccttacatt gcttctgtga gatgtttttt tcttatctga gatgaacttt     3180

caggagccta tttgaactcc agactggtgt tctggggcaa agagctatta gccaaactga     3240

ttctatgcag gtgaaggatg cactaaagtt ctcactttag tgagaacttt tctagctatt     3300

ccaatacaga gttctttctt atagggctat tgatattgac accaaatgga gtggcttctc     3360

agcctcttaa tgtcttaagt aagtgcttaa tttggaatag agaaaccagt atattttaaa     3420

aaagaaaaat attctttgta gcaactgtaa attctcccat tataacagtg aacagagctc     3480

caggtaataa cgcataggca tgtcaggttg catctgtata tttgactaca ttagtattag     3540

tgacatcagg tggatataaa agaaaaccct tggaaagaga actgccttag ccatgatttc     3600

gttagtagac ctatttatga ttcaattgca attttcagat aggatgtgaa catggaattt     3660

cattgaaaat agtttaattt tttatataaa aggttttgta tataatgtgt gtcagtgact     3720

attttcaaaa tcattttcat caagacacct tttttctaaa ataggcattg catacacata     3780

tgcacacgta tgtgcatgtg ccacacattt tttgtataat gttgggtttg attataaaag     3840

tgttgtcaaa tgttttattt atctgcatat agcagtggtt ggcttttttg aattgaaatt     3900

tttgcgcatt gatgcattga aataaggaaa attatttatc tctgagcact aaacttattt     3960

ttgcatattt ctgtaatatt gcagtcccca gatccagaac atgggaagtt agggaaaatg     4020

tgtgattttg tgttttgaat tactgtcaga attacataca caattacaac aaactttttt     4080

taaaagacat ttcattgtac tgcaaaaatc tgaatattta tatttcttgt ttttttcttt     4140

atatgttttg cattttaata tgttgagcca ctggaaattt gtaacagatt aatttgttat     4200

aggagtttaa atgtgttgtc attgtctcca ttgtctttgt ccagagccta ttattatgga     4260

aacaataaaa tttattgtgt cagttgcttt gattcttta                            4299


<210>  1842
<211>  2468
<212>  DNA
<213>  homo sapiens

<400>  1842
gcgttacagg ccctttggcg cctgcgtatt cgtgaagtgt gaaaaaagcg cgcctctgtt       60

gggacgggaa atcagccttt ctattggtca gggttagaaa ccccgccttt gaggcatttt      120

caaccaatgg aagcgcggca ttcttcattt aaactgtcta taaatttctg cctagtcaaa      180

gttaagagtg gcgccaggga tttgaaccgc gctgacgaag tttggtgatc catcttccga      240

gtatcgccgg gatttcgaat cgcgatgatc atcccctctc tagaggagct ggactccctc      300

aagtacagtg acctgcagaa cttagccaag agtctgggtc tccgggccaa cctgagggca      360

accaagttgt taaaagcctt gaaaggctac attaaacatg aggcaagaaa aggaaatgag      420

aatcaggatg aaagtcaaac ttctgcatcc tcttgtgatg agactgagat acagatcagc      480

aaccaggaag aagctgagag acagccactt ggccatgtca ccaaaacaag gagaaggtgc      540

aagactgtcc gtgtggaccc tgactcacag cagaatcatt cagagataaa aataagtaat      600

cccactgaat tccagaatca tgaaaagcag gaaagccagg atctcagagc tactgcaaaa      660

gttccttctc caccagacga gcaccaagaa gctgagaatg ctgtttcctc aggtaacaga      720

gattcaaagg taccttcaga aggaaagaaa tctctctaca cagatgagtc atccaaacct      780

ggaaaaaata aaagaactgc aatcactact ccaaacttta agaagcttca tgaagctcat      840

tttaaggaaa tggagtccat tgatcaatat attgagagaa aaaagaaaca ttttgaagaa      900

cacaattcca tgaatgaact gaagcagccc atcaataagg gaggggtcag gactccagta      960

cctccaagag gaagactctc tgtggcttct actcccatca gccaacgacg ctcgcaaggc     1020

cggtcttgtg gccctgcaag tcagagtacc ttgggtctga aggggtcact caagcgctct     1080

gctatctctg cagctaaaac gggtgtcagg ttttcagctg ctactaaaga taatgagcat     1140

aagcgttcac tgaccaagac tccagccaga aagtctgcac atgtgaccgt gtctgggggc     1200

accccaaaag gcgaggctgt gcttgggaca cacaaattaa agaccatcac ggggaattct     1260

gctgctgtta ttaccccatt caagttgaca actgaggcaa cgcagactcc agtctccaat     1320

aagaaaccag tgtttgatct taaagcaagt ttgtctcgtc ccctcaacta tgaaccacac     1380

aaaggaaagc taaaaccatg ggggcaatct aaagaaaata attatctaaa tcaacatgtc     1440

aacagaatta acttctacaa gaaaacttac aaacaacccc atctccagac aaaggaagag     1500

caacggaaga aacgcgagca agaacgaaag gagaagaaag caaaggtttt gggaatgcga     1560

aggggcctca ttttggctga agattaataa ttttttaaca tcttgtaaat attcctgtat     1620

tctcaacttt tttccttttg taaatttttt ttttttgctg tcatccccac tttagtcacg     1680

agatcttttt ctgctaactg ttcatagtct gtgtagtgtc catgggttct tcatgtgcta     1740

tgatctctga aaagacgtta tcaccttaaa gctcaaattc tttgggatgg tttttactta     1800

agtccattaa caattcaggt ttctaacgag acccatccta aaattctgtt tctagatttt     1860

taatgtcaag ttcccaagtt ccccctgctg gttctaatat taacagaact gcagtcttct     1920

gctagccaat agcatttacc tgatggcagc tagttatgca agcttcagga gaatttgaac     1980

aataacaaga atagggtaag ctgggataga aaggccacct cttcactctc tatagaatat     2040

agtaaccttt atgaaacggg gccatatagt ttggttatga catcaatatt ttacctaggt     2100

gaaattgttt aggcttatgt accttcgttc aaatatcctc atgtaattgc catctgtcac     2160

tcactatatt cacaaaaata aaactctaca actcattcta acattgctta cttaaaagct     2220

acatagccct atcgaaatgc gaggattaat gctttaatgc ttttagagac agggtctcac     2280

tgtgttgccc aggctggtct caaactccac caaatgtact tcttattcat tttatggaaa     2340

agactaggct ttgcttagta tcatgtccat gtttccttca cctcagtgga gcttctgagt     2400

tttatactgc tcaagatcgt cataaataaa attttttctc attgtcatag aaaaaaaaaa     2460

aaaaaaaa                                                              2468


<210>  1843
<211>  1509
<212>  DNA
<213>  homo sapiens

<400>  1843
ccgttgcgcc tgcgcgcggt gcggccgtcg cccctctttt cgcggcgttc tccacctgcg       60

cgggcctgaa tggccttcag gagcacagtc ggcctgagga gttgacggtt actcaccgcc      120

gtgagcccaa gtaactcgcc ctccttcggc tagaaaccct ccgcctgggc ccgcgcgaca      180

ggagcgcggt ctctgagggg agcggcgacc ccgccagccc cggtctcttt ccctggcggc      240

ggcggcttct tccgtgggac aatatgttca agagaatggc cgaatttggg cctgactccg      300

gcgggagagt aaagggtgtt actatcgtta aaccaatagt ttacggtaat gttgctcggt      360

attttggaaa gaaaagagaa gaagatgggc acactcatca gtggacagta tatgtgaaac      420

catatagaaa tgaggatatg tcagcatatg tgaagaaaat ccagtttaaa ttacatgaaa      480

gctatggcaa tcctttaaga gttgttacta aacctccata tgaaattact gaaacaggat      540

ggggtgaatt cgaaataatc atcaaaatat ttttcattga ccctaatgaa agacctgtaa      600

ccctgtatca tttgctaaag ctgtttcaat cagacaccaa tgcaatgctg gggaaaaaga      660

cagtggtttc agagttctat gatgaaatga tatttcaaga cccaacagca atgatgcaac      720

aattattgac aacatctcgt cagctaacat taggagccta taagcatgaa acagaatttg      780

cagagcttga agtgaaaacc agagaaaaat tagaagctgc taagaaaaaa acaagctttg      840

agattgcaga gcttaaggag agattaaaag caagtcgtga aactataaat tgtttaaaaa      900

atgaaatcag aaaacttgaa gaagatgacc aagcaaaaga catataaaca gttctcatga      960

gaacttggta gtaagctaaa ctgaaaataa ggtgggcttc actggagaaa tggacttact     1020

gcaaatgctg tgatgtttct tagaggaact tcatatacag ctgttgacca tgaatttctt     1080

agcaatagga atttgtacta tttaagcaat ctttaatgga aaatatgtgt gtaagaatgg     1140

atgctatata ggtattttac caacccattt taagaaaatt ctatgatatt aagcacagtt     1200

tttaaaaatg tttattgtag tatatgtata gcttattacc cttttgacag gcatcaaaat     1260

ttcattataa agtattactt gtacaaattt tgtacttctt tagtggctag aattagtgaa     1320

gaaacttaat gtgtatattt aatttcttca agttcttacc tgcccccatc cttttttgta     1380

tatgatgtgt ccagtaagta ttcaataaat gtagtttaca gatcctattt ctccctcctg     1440

atgtgtttct tcctctttga agactttctg gaactccctc aatacagtta aagtatcttt     1500

aaaaaaaaa                                                             1509


<210>  1844
<211>  1588
<212>  DNA
<213>  homo sapiens

<400>  1844
ggcgcctgcg aacccgggcc cgggggggac ggcgcccgcc aggagcgccc cccactccca       60

ggccagccca ccccggcgga ccgggccccg cgcgcccagg cgaggtgagg cccgcgccgt      120

cagggctgcg tgtcgccccg cgcccctgcc cagcccgcga ggactgcccc ctcccccggc      180

gcccgccccc acccccgcgc cccaggtgag ccccggagtc caggtaaggc tccgcgttgc      240

aggtaagagc ccctgagcgt agaggaggcc ttggcgcccg caggtgagag cccctcccct      300

cctaggtgac cctcaacctt cacggcgagg cctcctacct cctccaggtg ggggaccctc      360

tccccgatga accccctaaa ccaccagtga accccactgc tctccagatg aggtcgcaag      420

gaccaaccag tgcctacccg cccatgctcc cccgaaactg ggaactgaca gcccagcccc      480

tccaaagccc cttcctccag cttcagctgc caggtcagca agggtgaggc cggaagcagg      540

cgggtgactc accctgggca cctccgagcc tcagtttccc catggatgca acctgaggcc      600

tcctcactga gtcaaaaccg agacgcctct ggtccccgga gaggctgctg gctctgggga      660

aaggagagag cagcccagtg tgacagagcg agtccccacg gctctgggag tgcctcgcat      720

gtgtgtggcc caggtcctga cagcccacct actccctccc cggcaggcac tgggctccct      780

ctgctccccg tgggccgctc cccgcgtggg gccactgccc ccggcccccg ccatggtgcg      840

gatttcaaag cccaagacgt ttcaggccta cttggatgat tgtcaccgga ggtatagctg      900

tgcccactgc cgcgctcacc tggccaacca cgacgacctc atctccaagt ccttccaggg      960

cagtcagggg cgtgcctacc tcttcaactc agtggtgaac gtgggctgcg ggccagccga     1020

ggagcgggtg ctgctgaccg gcctccatgc tgtcgccgac atccactgcg agaactgcaa     1080

gaccactttg ggctggaaat atgaacaggc ctttgagagc agccagaagt acaaagaggg     1140

gaagtacatc attgaactca accacatgat caaagacaac ggctgggact gacccccgct     1200

cccccgacgc atgtggctcc agcccggcct ggccgccagg gagcgccact ggcttcccgc     1260

cacccgaagg gagctctgga ccctcagagc ccctgcagag gacggatcta gctcctgtat     1320

atatatttta ttgcatgcac tgtgaccttg gggggagaac agaaggggga cgacgccccc     1380

gcacctcctg cgatctggct ggcttggatc tcgtttttaa cccgttcctg ccccacctgc     1440

cctatagtta tggcctgtgt tctgctctcc tggtcccagt gcaccgtctg ctctgtgaac     1500

tcctcccacc aggcccttct taccccacgc gtgtctgtcc ccctcgttct gtagcgtttg     1560

tacataataa aacaatggag tggagaca                                        1588


<210>  1845
<211>  2105
<212>  DNA
<213>  homo sapiens

<400>  1845
agatctcatt ccgcctccct ctgtcgtcgc cccttcccaa ttctcgcgag acctcaagga       60

gcacagcttc tgcgcaccgc acgatactgg gagtccaggc gccaagggag ggggaaggga      120

aaaggggaaa cggtgcaaac ggcgtggccg ccatcttgct tgtgcccccg cttcgcgcgc      180

gctccgttct ccgtgacgca cacttccccc tcccctccgc cgcgcctggg cctctgcatt      240

gcccgactcc gtaggagcgc gggggcggct cctgctcttc ctggactcct gagcagagtt      300

gtcgagatgt ccacagaagg aggatttggt ggtactagca gcagtgatgc ccagcaaagc      360

ctacagtcgt tctggcctcg ggtcatggaa gaaatccgga atttaacagt gaaagacttc      420

cgagtgcagg aactcccact ggctcgtatt aagaagatta tgaaactgga tgaagatgtg      480

aagatgatca gtgcagaagc gcctgtactc tttgccaagg cagcccagat ttttatcaca      540

gagttgactc ttcgagcctg gattcacaca gaagataaca agcgccggac tctacagaga      600

aatgatatcg ccatggcaat tacaaaattt gatcagtttg attttctcat cgatattgtt      660

ccaagagatg aactgaaacc tccaaagcgt caggaggagg tgcgccagtc tgtaactcct      720

gccgagccag tccagtacta tttcacgctg gctcagcaac ccaccgctgt ccaagtccag      780

ggccagcagc aaggccagca gaccaccagc tccacgacca ccatccagcc tgggcagatc      840

atcatcgcac agcctcagca gggccagacc acacctgtga caatgcaggt tggagaaggt      900

cagcaggtgc agattgtcca ggctcagcca cagggtcaag cccaacaggc ccagagtggc      960

actggacaga ccatgcaggt gatgcagcag atcatcacta acacaggaga gatccagcag     1020

atcccggtgc agctgaatgc cggccagctg cagtatatcc gcttagccca gcctgtatca     1080

ggcactcaag ttgtgcaggg acagatccag acacttgcca ccaatgctca acagattaca     1140

cagacagagg tccagcaagg acagcagcag ttcagccagt tcacagatgg acagcagctc     1200

taccagatcc agcaagtcac catgcctgcg ggccaggacc tcgcccagcc catgttcatc     1260

cagtcagcca accagccctc cgacgggcag gccccccagg tgaccggcga ctgagggcct     1320

gagctggcaa ggccaaggac acccaacaca atttttgcca tacagcccca ggcaatgggc     1380

acagccttcc tccccagagg acccggccga cctcagcgcc tcctgcaggc taggacactg     1440

gtgcactaca ccccatgcct gggggccgag attctccagc agaaagatgc aatatttttt     1500

gtttcctttt tttccatttt tttctctaag gaatcaatat ttcaatatgt tgagtgtgtg     1560

tccaatgcta tgaaattaaa atattaaata acatatttat ggcattttct tgaagagtgt     1620

ggttgaagaa atatttctcc ttttgttttt cttttttttt tgtttgttac tgccacttct     1680

ttttaggagc aaatctcccc aggggtgtac ggtatttctt gactctggga acagctgcta     1740

cccccaagac ttgccacgtt gttctgccct cagatggaat taggtgaatg tgtgtagctg     1800

ctttttcact cgtggtcctc tccccatccc ttgctctgac cccagagctc tgtgtatttg     1860

catccagagg ccatggaaac attctttgca tttaagagac agatttattc cctgtggaga     1920

gtgggtggat tcattgccac actcttttct cccagggacc caggaaacta ggactttgtg     1980

tgtttgctgc ccacctccct tttatttttt aaatgcatta aaaactgtgc tagtctcctt     2040

tgcatggact tcaagctgca tgaaatgcaa taaatctcat tttagataaa aaaaaaaaaa     2100

aaaaa                                                                 2105


<210>  1846
<211>  2594
<212>  DNA
<213>  homo sapiens

<400>  1846
gtgtgtgtct gagggtgtgt gtgtgagtgt ggctggcccc agtacctggc caagcccacc       60

acttccacct gggccctaca cccccacaat gtgtacccct cttatctgcc ctggagcctg      120

tacagccatg ccacgctacc cctgagagtc tagaaagctg gtcactaact ttgcagacgg      180

atgagccttg agcacccaga ggagactggg gctgtcaacg ctgccccttg tcctgccggc      240

ttggatcccc tgacagggtc cttctaggct tcagactggc accctgacca tggaaccctg      300

aagtggcagt gacttctaga gctcagtggc agaccccacg acccttcctc ccccttcctc      360

cccctcccac caccagcttt caagctccca gagggagggg tggggagggg atcctgatct      420

cacagggcag ggggcttcca tcatgatgct caactcagac accatggagc tggacctgcc      480

gcccacccac tcagagactg agtcgggctt cagtgactgt gggggcgggg cgggccctga      540

tggtgccggg cctgggggtc cgggaggggg ccaggcccga ggcccagagc cgggagagcc      600

tggccggaaa gacctgcagc atctgagccg cgaggagcgc cggcgccggc gccgcgccac      660

agccaagtac cgcacggccc acgccacgcg agaacgcatc cgcgtggaag ccttcaacct      720

ggccttcgcc gagctgcgca agctgctgcc tacgctgccc cccgacaaga agctctccaa      780

gattgagatt ctgcgcctgg ccatctgcta tatctcctac ctgaaccacg tgctggacgt      840

ctgaactcag cctgtctccc acctcccggg cctctctggg gcccctttcc accgctcact      900

gcttagaaag gccgcatcct ccccgagccc ttataccttg gcatggagtc ccaaaggccc      960

tgggcacagg cagagagccc accggctggt catgagggcc tcttcctttc tctgacccag     1020

gcacctcgag ggctattctc ctgggttcct tccggggttt attgctgagg cccagctgtg     1080

cagaattgtt tgctagtgtg gttggtatgg aatccttgct ggctttacta agccagccac     1140

acttggagtc tgcccccaag ctctctcact gaatgctgcc tcttctaccc ctatgtccaa     1200

attttcagcc accacagacc tcagctgtgt atcctatctg ttctagcttc tcctgcccct     1260

ggtggggatg ggctgtcaga attgcaaggg aggaaggctg gggttagagt ggggagtggg     1320

cttcttcctc caagatctca gtctctcagt gcttggcaga ggggtgaggc cctggggagg     1380

caggggttgg tgccctgact cctgtgaggg gaatctcagt agctgggaat tatggaaaaa     1440

ctcttcctgt ttctgtccat cttgttcctg tggcttagca catacagacc tcagatctta     1500

cttggtagtg agtgccttgc cctctttgag ctatttggct acttccctgt ccctctgact     1560

cctactgtcc caattttctc cctccctgtg tgtcactaga gaaaaaaaaa aacaaaaacc     1620

tagattccgg attaggggat gacatcccaa acagcccgga gtatttgcag aaggctcagg     1680

caacgagtgg gccacatctc acttctgctt cctcatctca gcccactctg aaaatgtgca     1740

gcaccctcac tggttcctcc ccccaacgca aggaggatgc ccaattgttg ccctctgaaa     1800

atgcacagtt ctcctggccc taggacttac ttattacatt tttttctctt tccttgagct     1860

gcctttggca agggaagaga cccccaactc tgcgccccta ctccatgctg ctgatcccca     1920

cctgcgcact atagctcagg gtcagcagtg gaatgaaggg ccttagaacc tgcatagaag     1980

aaatgaactc actgcatttc tgtgctccct cctccctcgc accaaactcc tagctctaca     2040

agtatattta tttatttatt tatttattca tctatttatt tacttattta tttatttata     2100

aatattgcta tttattgccg agttgtgcac tttggggtag agtgaggggc tcccagcagc     2160

tctagctggg tctctcttgc ttcctccctg cttacgcctt tccttttctt gctccttctt     2220

caactcctgg tgtgtgtgag catgcccttt gcttgccaca ccatatcctt tccccagatc     2280

cacctgtcct gacactctag tcctccagga tagtgctcct cccccagctc cagggctcct     2340

ggatgtcctt cctcaactcc ctccacccct agacaatcct acctggtccc atctgcctct     2400

tttctctccc cagcctgccc tgtgaccctt gcctcttcct gatactccca agagcaggcc     2460

ccaggggtct gtgtcacata tctctgtgtg attccttctg gttgcatccc caatttcata     2520

caaaaagaaa aataaaagtg acctcgttct agcaccagga aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaa                                                       2594


<210>  1847
<211>  4494
<212>  DNA
<213>  homo sapiens

<400>  1847
accagactgg ccgcctctcg gcgagcgcgc cactctcccg tcgccgctga cccgcgcgcg       60

gccgccgaag cctccccgcg gggacattca ttcttgcccc ttgcctgtcg ccgggccggg      120

cgtacgggcc gcgttgtcgg gggttttgtc ccctttttcc tctttttttt ttccttctcc      180

gccccccccc cttttttttt tttttgcttt ttttttcctt tctgtttttg ttgttgttct      240

tgcctatgtt cgggaaacca gacaaaatgg acgttcgatg ccactcggac gccgaggctg      300

cccgggtctc gaagaacgcg cacaaggaga gtcgggagag caagggcgcg gaggggaacc      360

tcccagccgc cttcctcaag gagccgcagg gcgccttctc agcgtcgggc gctgctgagg      420

attgtaacaa aagtaaatcc aattccgcag cggacccgga ttactgccgc cggatcctgg      480

tccgagatgc caaggggtcc atccgagaga tcatcctgcc caagggcctg gacttggacc      540

ggcctaagag gacgcgcacg tccttcaccg cggagcagct ctatcggctg gagatggagt      600

tccagcgctg ccagtacgtg gtgggccgcg agaggaccga gctcgcccgg cagcttaacc      660

tctccgagac ccaggcaaat agtgaagaaa ataatgaacg attcaaacgc gggataaaaa      720

aacaaaagaa gaaaaggaag aaagagccag caaatgatga gtctcggcgt ggggactccg      780

ggggcagagg gtggcagccc ctatagtgcg gggccctgcg actggtaccg tgagcgcctg      840

ggatgaggtt tgggcggatt tcgggtttcc ggagaggcag agacgcctgg ctacgacgat      900

ttgttccact tccttgagtg tttcgctctc gatttctcta tctgtccctc tgaggtcggc      960

ccctcagacc ctcctcctta atttcccact gcgtaattct tagtttattt aggaactcat     1020

ctctgggcac tataaagtct ctgcctccta atgctaggtt tctagagtct tccagctgca     1080

tcttcatgcc ggcagcattt tggattttgt gcaatcatgg gcccagaata ggcaaggttt     1140

tattttcttc tgacttagaa tataagtctc gccatcgtca aagagaaact ttgaaggagc     1200

aggagactga aatcgatatt aattcctgca aagagacctc ctcaccctgg tgcttatgcg     1260

gtggtgacgg gtgtagacgt tgcaaacaaa tcttgggaag cgaggagggc cggggaggac     1320

acttccggac acgctcttct aaagcgtgtg cagcacgggg cgaagtccgc gctgcggggg     1380

cagcggcccc ggctccttct tgtagcgcct gcacacctgg gtgttgcagg gacccgcagc     1440

tcccgtgcgg caccggccct agccaggcct tactgcccct actcgtgtac tgtgcctgaa     1500

gctgaagttg gaggcatcca aaataaggcg gggcacagtg tgggcggcgg agtccctgag     1560

ccttgagctc cgctttttgc tgagatcaca gcagccgccc acagacagtt cacttttatt     1620

tctcaaagtt gctgcagatc cctcagcttg gcttctcttg gctcttcccc tccctgtccg     1680

cctctcctta ctttctcttg cttgaaactg cttttccttt tctactcttt tcttccgcgc     1740

tcctgtcccg taaacgcctg cgcttccttt aaggagttct ctctctgtgg tgtgggctcc     1800

cctctcgttc cccctgtctc cctcctccat tacttcttcc ttccaggtct ctctctctct     1860

tttggttttc tggttttttt ctcctgctca aggggtccca aaggccaagg cagtgggtgg     1920

ctctcgctgc agcttcaagg ctggtggctg ggaccctcca ggggtgagaa ggaagggaga     1980

aggtggcata actttttgga acaaaagaaa acacaaaatc ctagcttggg attcccaaca     2040

aattcagcct cctctcccag gggcctcagc ctgggaagtc accaagcaga tccctccttc     2100

cagcttcctg ctctttctcc tttttgcttt cttacccctg aaagagggaa ggacaagtca     2160

cctcataact tctgctctca cctcccttcc ctccctggct ttgggaagag ctgctgagct     2220

ctttgcctgc cactcaggga gtgcaattgt tcttaaagag cctcttctgc atagaaaaag     2280

aattgcaatt ttaatttaaa aacatttata gaaaattcat ttaattttag tgactatctt     2340

cttttccctc cttccccaag ggcctccagt aagctgcctt ggtccctgga ggcttctggc     2400

ttccaactgg agactcacag gccttggagg aggaggcagg taccctctat gccaatagct     2460

gggcctgcct ggggaaaggt ggaaggagaa acagctgcag gaggggggag ctgaaaggaa     2520

tctgatgctc aggcctgcac aaagcaaccg ccaaattgtt tcagagcaga aaagaaaaag     2580

ggagaaaacc tcttagcaaa gccctgtgag tttgggggtc aggttcaaga aagatgtggg     2640

aagtcacttg gagagctaaa cgggacacat gctcctatcc acacttgcag ttggtctaac     2700

cttcagccag aatgtattca taagtagcat ttggcaaccc tttatagttt acaaatagca     2760

ttttacatac accattctac tattcctcat ggtggctttg ggaggtccag ctccgtttta     2820

aagactcaca caggactgaa gcaaataact tgctcaaagc cacatagctg ctcagaaccc     2880

aagattgtaa gctcccccta gggccagagg cctctttctt tcagtttttt tctttcgtcc     2940

ccctttgacc cctctttcct tcttcccttt ctcccctcct tcctcctttc cttctttttg     3000

tgcccacagt gtctggatca tggtacctga attctttagc ctatttgcac ccacatctgc     3060

taatgtccat atctagccat ctattacacc agctgctgag gatttacttg gtgccctcat     3120

caagaagttt gaatttctcc ctccttcctt tttttttcct gccactgtcc caactctttc     3180

cctctacgtc tctctagaat gacatcttta aaccccttac actctttggt cttacacatc     3240

cttaaaaatg attatttata aattgaatta taatatccat gaggtaaaca ctcatagggt     3300

aaagtacaca aagcttaact atacaagttg atgatttaca cacacacaca cacacacaca     3360

cacacacccc ttcttgaatg gctccaagga taccctttta acttcttccc ttcagccaca     3420

taagccatat gatgacacac agtgtctttc tcctgtttga aaagaaattg tgtcatattg     3480

gtgtgctgtt cttgcataga aagccttttt taagaagtct ttttaagatt tcttgaagga     3540

ttttagaaat catatatctc ttctaacccc ctgaaatcct gagtttaagt ggcttgatta     3600

aatggctgat caaaacttaa aaacacacta ggtcaatgtt tttcaagata caactgagga     3660

ccagctgctt cagaatcatc tggggactgg ctaaaattcc aggttcctaa gccctagtcc     3720

catctgatga atcagaaact aggttggggc ttaggaacgt gcattttaaa cacttttcca     3780

aagtgattct tatccagact aatatttgag aagtactgta ttaaatggca aactcccaaa     3840

acactgcagc ctcctgcatc tggcccaggg cctggcattt ggtaggaata caatgaatgt     3900

ttgttaaaca aattaatcca cagtttctga cacagtttag aatttcttgg accacattat     3960

gctattgtaa tttaacacca tttctacgtc gggaaatctt tacatttcag tctttttcat     4020

tttcatggag gtttcatttt aatggagcag gagagaaaag agagatctac tttggtggtt     4080

tctcaggtct cagggaaggt cttttataaa ctcaatgggg accaccttcc tggagaggct     4140

gctcccttac agacctggta gtttggggaa aggaggagga gagcccttca ggtttgctga     4200

aaagcattca gatgcacacc cttcttggtt ggaactgaaa gcttctgttt gaagagacat     4260

gagttctgga aggagcaagg ccaccaggtc cagagaacct ggcatgcaat ggacatggaa     4320

gctgaaaatt acttgggtat tctctgattt ctagctaata tgaaaataat tttctttcta     4380

gaaacacatt tgcctatctt cttaccctga aacagaaaat aaatattgtg ctttatgtgg     4440

tagtgttgta cccattctta aaaataaatc acatcatata tatgtgtaaa atat           4494


<210>  1848
<211>  1968
<212>  DNA
<213>  homo sapiens

<400>  1848
accagactgg ccgcctctcg gcgagcgcgc cactctcccg tcgccgctga cccgcgcgcg       60

gccgccgaag cctccccgcg gggacattca ttcttgcccc ttgcctgtcg ccgggccggg      120

cgtacgggcc gcgttgtcgg gggttttgtc ccctttttcc tctttttttt ttccttctcc      180

gccccccccc cttttttttt tttttgcttt ttttttcctt tctgtttttg ttgttgttct      240

tgcctatgtt cgggaaacca gacaaaatgg acgttcgatg ccactcggac gccgaggctg      300

cccgggtctc gaagaacgcg cacaaggaga gtcgggagag caagggcgcg gaggggaacc      360

tcccagccgc cttcctcaag gagccgcagg gcgccttctc agcgtcgggc gctgctgagg      420

attgtaacaa aagtaaatcc aattccgcag cggacccgga ttactgccgc cggatcctgg      480

tccgagatgc caaggggtcc atccgagaga tcatcctgcc caagggcctg gacttggacc      540

ggcctaagag gacgcgcacg tccttcaccg cggagcagct ctatcggctg gagatggagt      600

tccagcgctg ccagtacgtg gtgggccgcg agaggaccga gctcgcccgg cagcttaacc      660

tctccgagac ccaggtgaag gtctggttcc agaaccggcg caccaagcag aagaaggacc      720

agggcaagga ctcggagcta cgctcggtgg tgtcggagac cgcggccacg tgcagcgtgc      780

tacggctgct ggagcagggc cgcctgttgt cgccgcccgg cctgcctgcg ctgctgccgc      840

cttgcgccac gggcgctctc ggctcagcgc tgcgcgggcc cagcttgccg gccctgggcg      900

cgggcgccgc tgcaggctcg gccgccgcag ccgccgccgc cgccccgggc ccagcgggcg      960

ctgcatcccc gcacccgccg gctgtgggcg gtgctccagg tcccgggccc gccgggccgg     1020

ggggattgca cgcaggcgcc ccggccgcgg gccacagcct cttcagcctg ccggtgccct     1080

cgctgctcgg ctccgtcgcc agccgcctgt cctccgcccc gttaacaatg gctggttcgc     1140

tagctgggaa tttgcaagaa ctctccgccc gatatctgag ctcctcggcc ttcgagcctt     1200

actcccggac caacaataaa gaaggggccg agaaaaaagc gctggactga ttttaagtgt     1260

ttccctgtat ttatatttat agtatctatt gtggtgatat ttatggactc acgcgcatta     1320

ggtgcccaga gctcctgcgc tgggctcctg gctcccacca ggcctctgac agctctcctt     1380

tcccactaga ctctgctacc aatttcatct cattcgggct attttttttt tctactacct     1440

ttcctctgag attcctcccc aacccccaac ttccttctga atccaggagc gatccaaaga     1500

attgggaaaa atgcccgagt tagtcaacct gatgccctga ccccgtgccc agcccaggag     1560

ggaaaagact ggttctaact ccaaagcaca ggacgtttgc tctagatccg cggctgctgc     1620

ggctgctgcc gctgccgact attcctagga atatttgaaa gaggaaaact gcgcgcagac     1680

cccaggggct tccaggtttc tttagaccaa aaaaggagga cgttccttcc tcttgccagg     1740

gaaaccaggg cttgtgggag cccctgggcc ccgctttgcg gacctctcgg gatagtcggt     1800

acacaacaca gcttcctggc gggcaaatcc tgcggttttt ctccccttta gggcaactcc     1860

aatcacaacc acccccgacc ccaggaaaca gtaacaaacg tcgtagtagg caacgacact     1920

gataaatttg atctaatcag caataaaagc aattgctacg taaaacca                  1968


<210>  1849
<211>  10390
<212>  DNA
<213>  homo sapiens

<400>  1849
gtgcgaagcg tgaggtggag atgggggcgg agggagctgg agctgtcaca gtccccgggt       60

gcgcctgacc gagccaagtg gggtgtcatg gccgcggggg gcagcggctg cacttcctca      120

gcgggcggcg gtggccgggg agttaatcct cgacgcacgg gtcccgtttc cctctgtgcg      180

gcggccggcg ggaccataag ggcttaactc atatatttaa cccccctcca aaaaggtttg      240

aaagtattct tgaagggctg tttggacctg cattattaaa agatctcagt ttatttaaag      300

actgtgaacc tgaaagcatt tctgattgga cttttgatga aaactgttta ttctgttgct      360

tgagaagaga taaagtaaag ggacacttag tcggtctgga tgaaccagct tcgggagctg      420

ggcaagaagc tctgcttaaa caagagcaag caaaaatcat tcgattcgag agacaagcag      480

aagaattcct caatgcagtc ttttatagaa aagacagtcc ctgggtctcc gaccccaata      540

ttcccctagt ggcccgtgag atcatgcagc gaatgatcca acaatttgct gctgaatata      600

cctcaaaaaa tagctctact caggacccca gccagcccaa tagcacaaag aaccaaagcc      660

tgccgaaagc atctccagtc accacctctc ccacggctgc aactactcag aaccctgtgc      720

tcagcaaact tctcatggct gaccaagact cacctctgga ccttactgtc agaaagtctc      780

agtcagaacc tagcgaacaa gacggtgtac ttgatctgtc cactaagaaa agtccatgtg      840

ctggcagcac ttccctgagc cactctccag gctgctccag tactcaaggg aacgggcgac      900

ctgggagacc cagccagtac cgcccagacg gacttcggag tggtgatggg gtacctccaa      960

gaagcttaca ggatggaacc agggaaggtt ttggacactc cacatcactc aaagttccac     1020

tggctcgatc cctgcagatt agtgaagaac tactgagcag aaaccaattg tccacagctg     1080

ccagccttgg gccatctgga ttacagaatc atggacaaca cttaatatta tccagggaag     1140

cctcttgggc aaaaccacat tacgagttca acctcagccg tatgaagttc aggggaaatg     1200

gtgcactcag caacatcagt gaccttcctt ttcttgcaga aaactctgcc tttccaaaaa     1260

tggcacttca agcaaaacaa gatggaaaaa aggatgtgag ccattcatct cctgtagatt     1320

taaagatacc acaagttcga ggaatggatc tttcttggga gtctcgcact ggtgatcagt     1380

acagctatag ctctttggta atgggttcac aaacggagag cgcgcttagt aaaaaattaa     1440

gggctattct tccaaaacaa agtagaaaaa gcatgttaga tgctggaccc gattcttggg     1500

gctcagatgc tgagcagtct acctctggac agccatatcc cacatcggat caagaaggag     1560

accctggctc caagcagcct cggaagaaaa gagggcgtta cagacagtac aacagtgaga     1620

tactggagga agcaatctca gtggttatga gtggaaaaat gagtgtttcc aaagctcaga     1680

gtatttatgg gattccccac agtacactgg agtacaaagt aaaggagagg ctgggcactt     1740

tgaaaaaccc tccaaagaaa aagatgaaat taatgaggtc ggaggggcca gatgtttctg     1800

taaagattga attagatccc cagggagagg cagcacaaag tgcaaatgaa tcaaaaaacg     1860

agtaggaata ctgtagagtg ccaattactg tacaaactgg gtgagcacta ctgcatcatt     1920

gttcagctat cattgcttgc acgtaatttc atttactgtg acacttgctt ctttgcagat     1980

tttgcattga cttgtgtgta cagagatgaa atgtgcattc tgaatgttgc atattttaaa     2040

tttttcatgt gcagtatggc tcggaatatg tttggccttt tgcatgtttc tctacaaaag     2100

agaattgagt tacctcacag agaacagata catggaagtg gactccttgc ctgtagagcc     2160

tgcatgcttt tttgtttttt tttgttgttg ttgttttttc ttaagttata tttgttttta     2220

ctttttaaaa aagaagagga aacaaagccc ccttttagaa actacgtctg tcatactggg     2280

agctttatca ctgcaaattg gaaagccatc ttatacaaaa ttattcacat ttttcatcta     2340

cgattcaact aatcgaagga ttaaactaaa gaaaaaacta agaagaacaa tgaacctttg     2400

actttgagaa atttggttat tcactgacat aattattggg tcatttatag ttacatttta     2460

taattttctt ctcactatta aatttattta aattagcaag ctattagtgc tcacccagag     2520

gggaaggtgg tggaaaatgt gcacacacta ccttcagaaa tgcttcagtt aattactttg     2580

aacactacct ttgctgtaat ttcatttgag attttctaag ggtagaattt ggtctcacca     2640

acaagtgagg atatagcctt atctcatgga ggacgagctc cgtatttact caggagcagt     2700

cagggtacat tacataaaac aatggaggat gcctcatttt agcaaactag gtttctttgt     2760

attcttcagt ccttttacag aattgatgtg ctaactgaat atcattgcag caactagact     2820

aagatattca agatctcttt attggggatg ggagaaatag ggaaagaaat gtgtataagt     2880

aattatgata ttgcaaaagt gatacttaga ttttacagcc tcagtagtct gcccagtgtc     2940

cacattaatg aaggatccat gtttgtagtg agagaaaaaa accccaaggt aacccgatat     3000

gatttaggat gcatatcagt tctaacaatt caatcagaag tcaagctcat tggaattcct     3060

tttttaactg atccaaatac tagtagaagg gggagggaga ggtgttgggt ttttttttta     3120

agtttttatt taattttgtt ggttagaatt tttttctgtt tttggcatcc tacataatac     3180

cccccttctt gactttttct gataattagc tgatattcat ggttgtttag cacacagttc     3240

aggacctttg agatcatgtt tgtataagca ctccttgaag aatatctaag ctttttctga     3300

gatgggcttt taaaattata ataagggaag tttattttct gcggtttttg caagaataag     3360

caaagcccat ggaatttaat ttttcattgt gatcagatta aaattactat ttgtgcaaaa     3420

caaattccac accacatgta ctgtatattc taatctgctg agaaaggtgg tcaggccctt     3480

ctaaatgctt aaccaaaaac aaacattatt ggagtttcag tgtaaaataa aattaaaatt     3540

ggagggttgg ttagattgat ttcagatgga tactaacagt ttgaggggag gtccagatat     3600

ttccaaggca taaattcttg cctggaaact ttggagcaat taattaaatt aggttaagtt     3660

ttccctcagc aacctgtgtg ttcaaaggtt aggcacacca ttgctgttac taaaatacat     3720

gcactgctca ttcttgacat agcttgggtg tgggttcctc ttgttttggt tattttgtgt     3780

agcagtttaa tcagtggata actgagcctg tttcctctta gctttctaga cttcttaaca     3840

gaaaaaacag tttgggttca atagcatttt atgattctac aatattttgt cacctagctg     3900

gaagttgcaa taaaaattcc ttatgaaata tatggttttc atctgtaatt gaaggaaatc     3960

atagaaagtt tgctgaaagc aaagggctaa gcttatgaag gaatgcctcc tttgttacac     4020

actcaagaat ttgtcagcac acaattaatt gcagccatag tacctttttg cgtaatgttt     4080

gggatattca gtagcccagg attgctacaa aaaggtcctt tgagaaaatt aatttgtgct     4140

tgcttttatc ccctctcaga aagacatcac taaaggccca ttaaaaatct ggccctaaaa     4200

gttcaacttt tgtagagttt attgttcaga gaggtttaat cctatgtggt agtctatata     4260

agtgatgtat gagttgagtt atgtaaattt tgtcattgta gtgtacatgg agtgatcatt     4320

ttactaacat aaatattttc tatgtgtgtt tcagtggatg acaatcgagc agcagaagaa     4380

tggtgtgcct accctttaat gctgcagttt aagagaactt gtattgtgtc atttcagatt     4440

gtaggctgag agttgtaaat agtgaaaatt tgagtacttc tattatttgt tttggttaga     4500

aagtgaattt aaaaaacaaa ccaaactcta aactttctca gattaaaagt cctgagacct     4560

gaagattgta atattcatgt ctgtgaagct tttaaacatt acacttgaga tcagtcatga     4620

cttgatattc aggtaaattt tcttttccaa gaagcttttg aataagcata tttcctccaa     4680

aggtctctct ctttctctct ctttttttga gtgtagatta ttttaaagca ctaattgcat     4740

tacattggta actgcaatat aaaatagcca ttattgtttt gtgaagcatg gttgaaatta     4800

gctagtggtc ccttttgaat ttcatgagcc tctcaaaaaa gaaaaactta aaaaaaaaaa     4860

aaaaaaaaaa caaaaagctg ctggaatatt tcaaaagata tatattttac cttattatag     4920

gttttgtaaa gttagtttgt aatattcagg tgcactttta atgttaaatt ttgtgttcag     4980

agttccatta taccatgtat ttctcggagg tggctcatca cacggctggt ggcagtcttg     5040

gtgccgcagt gattccttaa tatttgattt ctctcttgat ttgccactat tctgtattgg     5100

cactttcagt gtagatattc tagtttgggg atgtcctcac aatgtgtaat agagattggt     5160

ctattagcat gcttaatttc tgctaatcag agttttgcat ggcccaaaca acagttgacc     5220

atttttatgg tatgggaaag tgtagttcac aactgtcttt gtcacgaaag ccgtttttcc     5280

tcacattttc cagtaggcag ataacattac ttaaattatt aatatataac actcttggaa     5340

ctattgatag gaaataatgt atttaaaata attttttgca ttttcagaga ccttgatgtt     5400

atagggtaga taagctatgg cactataaaa tcaaaaacac taattctgtg gaaggatatc     5460

tagttggtat ttttatcttt agctttctca tttctgagac agcatagtca tccagcttga     5520

tggtaatgta gtatattact ttgttcagtg ggcttataag tgactctgaa ttatgtttgt     5580

gatgagctat acactttttt tctgttcccc aaataccatg aaggacaagg tcactctttc     5640

aggaaaaata atttatattt gtgtataata ctttttaata ttaagtttgt tgttctgaag     5700

tttagatgtt gcttgataaa cctttgctgc agcagatcat gaatatgagt aaggctttgt     5760

gtgataatag gggtccttat gtgaagttaa ttactgttca gttctggtga gcaagctcaa     5820

caagtgtgaa gtgtgtatta gctttatttg gtacactttt actttacaat atcgaagtgc     5880

ttttagaact ctggttatct tatataaacc attacctcaa ccaattggca tttcttttcc     5940

ccaacattta ccttagctat aatatgagct atgtgggatc agatggtaaa actataaaag     6000

gcacaatgag aagtttagtt cccaagtttt ggagagaact ctaaattaga ctaaaaacaa     6060

ctacctgtta acaccaatat cataactacc ttctgtcgtt aggcagtaca tagcaacctt     6120

tgagctgcta gtgagctatc tgttctcccc ctacccccaa gtaagcacac agtgccaggc     6180

ctggttctaa gcctttgtga ttctcttaca tctcattgac ccataatagt gaagcatgga     6240

ttcatttatt ttcataagac aaattgagtc agctcgatgt cagaagttga aaatattttg     6300

agtagtttaa cagttatatg agagattggc atcattttct ttaacagctt ttatctttgt     6360

agatttcctt ttgagacatg tatttttgct tttataatcc tttcattaaa tgccagaggt     6420

tgttttcata ttaatcactc ttttctgtat attcaggttg ctgtcattgg tgatagaata     6480

tggcaataga cagaattgtg ctccacttta tgttttttag gagatattga aagttatagg     6540

ttaaattttg gccttcttga agatatcaaa gattgttttc cttgttacct ttaattagaa     6600

tttggtcttc attaatgctt tggtcaggct agcattacta aaaacttgat ggcttcagca     6660

gaacagcccg tttaggagac tattaagcta tctagggatt ttttttcaaa ttaattgctt     6720

tcaaaatctg aaaaggaaaa aagtataatt gtggtacaaa gaagacagat ctccaggctc     6780

tttcttctca gtttattttg gtttaattct gtactggaga cttgaatagg atttgtgaac     6840

atggtgatgg aaagaaaaat agaggacatt atttgtgtac cctcattcct gaataatctt     6900

gcagtcacct tttaaagaag cagacattag ccctgtaaca caacactgta gctataaact     6960

ctaagtgtta ggaaggagat tggggtgggg agggtggagt aggatggaaa aagcatgtag     7020

acttctgaga agaggctaaa aattctgccc tataatacta aaaatgagtc acaagataat     7080

gtggtgaagt taggccatct tgatttgata gaaaaatctt ttacattgtt taaaaatgag     7140

aatcgaggct aattaatgtt gatttgacaa tagaacatga gctaattctg caaccgtttg     7200

gggggtaatt ttatggtttc cagttcattt agagctgtat caagaaaagc taaaaagcaa     7260

gcacttttag ttaatcatag atttattgga tatagcaaat attattataa tatttaatct     7320

ctattatttg aatgtggaaa tgaactcttt taccccatct tgaactgtca ttgaacatgc     7380

tcaagatgat caacactgga aatgacccta cacacatacc aaaaaaatct aaagcagtaa     7440

gacatatttg aagatccata cctcttaaac tttttagatt tgtcttggga aagaatttat     7500

gaacctgtaa ccagtattag tgcagtcttg ggttccttgt tctgcataat tgcacccttt     7560

ctcaggtatg tcctgacaac ataaatttta aaataatctc attagagatt agattctcag     7620

tggatagtgt gtaaggggac taggggtggg gggttggggg tagttggaca caggacactg     7680

acacagtaga gcagggattt ttaacagtca atagccaaat agaatttcaa tctagaatat     7740

ttttaccccc tcagaatgag tgaaacaact tctattattt ggtgtacccg gtgctacact     7800

cctaaaagtc tttttttttt ttcatccagg tgacgttttt tatttttcct gcttggtggt     7860

ggaaggttat atagtaaact tcactgtcat taagaaagcg cttgtccaaa atgtttaaag     7920

tactagaaaa gggataattc agcacttttt ctgttacaac actaaagtct taatttatct     7980

tcagagtctt aggtactgta agtttttgga tgattattta aaaatataaa acatactaca     8040

taatatgggg tcagatcaca tttatataaa taattcttat tttaaaaaag acaataacat     8100

tttgtacctt tctagcaatt ccaagtgatt gcctcatttt ctcttgttaa gcatttcaag     8160

cttaagaatt tggaatttga gagaaggtga gggggaaaat tccctaaaat aaaaatttgt     8220

ttcaaaccat tttagaaaaa taaatcacta ggaaaatagg tagggattct ctcccccttt     8280

aagtcttcag ggaatgagca gtatttagaa tctttggctg aaattcaagc ctttttactt     8340

tgtaaatttt taatattaat tcactgacat gctttttaca ccagaggact gaaaatggat     8400

cttaatgttt ttaagttgtg gaagggtata tttctaaaat gaggggggat gattaactag     8460

gttagtatta ccagcattag taagtttaag gaattttagt atgtaatagc aaagtgtttg     8520

attaaaagtc taatcctata ttactagtca aaattagtta cattctgatc taggaaagat     8580

aatagtcatt ggatattgat atgctgtgct gtcagaaaac cagactaaga tagaaacctt     8640

tatctgactc ccacatgttg cttgttgtga tgggatgtat actttacagc agcttattgc     8700

tgctttgaaa aaaaatgtat aaactataca tttggagtgt ttgcatataa ttctttataa     8760

cctccactta aagctgtcag acattggtat tttatcagtc cacattgttg aataaaacta     8820

atgttcttag gaatccagct tgtacacact gtttaaaaac cctcagggac agtttacaca     8880

ctcttctcac tcaattcagg tactttgatg ctattcttaa acctaacagt gacttgtatt     8940

tttctgtttt gcttttattt caacgtgctg gtagcacatc tgatgaatgt caacttaaaa     9000

aactcagttc aggtatccag gtataactca gccaaacaga ttttaaagct gcatataact     9060

ctccagcaca tggtgcctca cactcttata gtggcattct atatattcag ttattactac     9120

tgagcagata atatgggggt tcctgttaac agtgtatttt ttaaaaaaag cgcataaatg     9180

tatagccagc acactacaca cacacacaca aacatgcaca gttaaactat atatttttaa     9240

atgccactaa tagccagcac aactaaaaca aaagacattc ctaactgctc tgtaagctgt     9300

taacagatgc agttccttct tgatgtggct cttgcttctt cacgataact actactaaat     9360

tcaagcactg gtccttgggt gtctgacctc tacattctag tttatgcaat gtctttagag     9420

aattttgtgc actggccact gtgatggaac cattgggcca ggagtgcttt gagtttatca     9480

gtagtgattc tgccaaagtt ggtgttgtaa catgagtatg taaaatgtca aaaaaattag     9540

cagaggtcta ggtctgcata tcagcagaca gttttgtccg tgtattttgt agccttgaag     9600

ttctcagtga caagtttttt ctgatgcgaa gttctaattc cagtgtttta gtcctttgca     9660

tctttaatgt taagacttgc ctctttaaaa ttgcttttgt tttctgcagt actatctgtg     9720

gttaacaaaa tagattattt ctctgcttta atatttgata tcttacatct aaaataaatt     9780

ctctccacat ataaaaccca tagcctttgg agatatggaa aatggtatct ttcagatttc     9840

tagaagttca agtgtcatac aacaaaacag gaaccccctt tactcttatg gacctcattt     9900

caatatactg tttacagttt gatggaattg tataatttaa tatttctctt gtactgtagt     9960

ttatatttat ttacagattt ttttgtactg tgtgatttga actttttgtt ccttgctatg    10020

atcaatgttt atgtagtaga gcacttatga tcacaaatta agttttttgg tttgattgca    10080

ctacattaaa ttttttaatg cagttctgat ttttgactgg actaaaactg tgtcttaatg    10140

tatgtgatga gtacttaaaa ttttaatcca tgtggtcccc cccctttttt ttttttttgc    10200

attgtatgtc aaaagcgctt gttctttcgt gcatgtgtaa gatttaatgg ttccattgta    10260

ttatttgacc atgacatttt ggagaaacat tcccagctgt aatgttgtgt atggtagttc    10320

tcactggatg ctagagtttt caaaaccact attcttctaa taaattttgt tgtgaaaaac    10380

tgttaaaaaa                                                           10390


<210>  1850
<211>  2272
<212>  DNA
<213>  homo sapiens

<400>  1850
gcgggcggct gtgagcggcg ctcggggcgc gctaggcggg gagccgagcc gggctggcgg       60

caggcggacg gggcgggcgc gtgcggcgcg agccgggcgc tgaggacaag ggccgctggt      120

agggccggcc ggccggcggg cggagcgccg ccgccgacgc acacgaggtg accaggcatt      180

gatgcacccc caggaaggcc acgcgctcag gaggcccccc cgccccgctg gctgctgctc      240

acatggtgtc tgggcccttg gcactctgtt catgcgggag atggcagggg ctggcacatg      300

acagtggagc agaaatttgg cctgttttct gctgagataa aggaagcaga ccccctggct      360

gcctcggaag caagtcaacc caaaccctgt ccccccgaag tgacccccca ctacatctgg      420

atcgacttcc tggtgcagcg gtttgagatc gccaagtact gcagctctga ccaagtggag      480

atcttctcca gcctgctgca gcgctccatg tccctgaaca tcggcagggc caaggggagc      540

atgaaccggc acgtggcggc catcgggccc cgcttcaagc tgctgaccct ggggctgtcc      600

ctcctgcatg ccgatgtggt tccaaatgca accatccgca atgtgcttcg cgagaagatc      660

tactccactg cctttgacta cttcagctgt cccccaaagt ttcctactca aggagagaag      720

cggctgcgtg aagacataag catcatgatt aaattttgga ccgccatgtt ctcagataag      780

aagtacctga ccgccagcca gcttgttccc ccagctgaca tcggcgacct cctggagcag      840

ttagtagagg agaacacagg ctccttgtcg ggcccagcga aggactttta ccagcgggag      900

tttgatttct ttaacaagat caccaacgtg tcggctgtca tcaagcccta ccctaaaggc      960

gacgagagaa agaaggcttg tctgtcggcc ctgtctgaag tgacggtgca gccaggctgc     1020

tccctgccca gcaaccccga agccattgtg ctggacgtcg actacaagtc tgggaccccg     1080

atgcagagtg ctgcaaaagc cccatatctg gccaagttca aggtgaagcg atgtggagtt     1140

agtgaacttg aaaaagaagg tctgcggtgc cgctcagact ctgaggatga gtgcagcacg     1200

caggaggccg acggccagaa gatctcctgg caggcagcca tcttcaaact gggagacgac     1260

tgccggcagg acatgctggc cctgcagatc atcgacctct tcaagaacat cttccagctg     1320

gtcggcctgg acctctttgt ttttccctac cgcgtggtgg ccactgcccc tgggtgcggg     1380

gtgatcgagt gcatccccga ctgcacctcc cgggaccagc tgggccgcca gacagacttc     1440

ggcatgtacg actacttcac acgccagtac ggggatgagt ccactctggc cttccagcag     1500

gcccgctaca acttcatccg aagcatggcc gcctacagcc tcctgctgtt cctgctgcag     1560

atcaaggaca gacacaacgg caacattatg ctggacaaga agggccatat catccacatc     1620

gactttggct tcatgtttga aagctcgccg ggcggcaatc tcggctggga acccgacatc     1680

aagctgacgg atgagatggt gatgatcatg gggggcaaga tggaggccac acccttcaag     1740

tggttcatgg agatgtgtgt ccaggctacc tggctgtgcg gcacaggttt agccccaaca     1800

tgactgagcg cgaggctgca aatttcatca tgaaggtcat ccagagctgc ttcctcagca     1860

acaggagccg gacctacaac atgatccagt actatcagaa tgacatcccc tactgaggag     1920

gggaccttcg agggcctctg ccccatgtgc ccttgaagct gccccacaat catggagccc     1980

tgcgacctac ccgccctgcc gccacatgca gtggaggaga ggcctgtggc ccgaagagcc     2040

tggtagcgcc tcctggggca gcacgtgggt ggcgcaggct tagtaacgcc gtggactgca     2100

gcgacaatca gtggatggtg ctgtctatgc acaggtgtga gtcctctgtt tgcactggac     2160

atattcccta cctgttttat ttcataggta catgaagtat tgtgtataaa aaaagagata     2220

agatttaacc aacatcaaca aaataaaaac ccaaaatagt gctgtgttgg aa             2272


<210>  1851
<211>  8304
<212>  DNA
<213>  homo sapiens

<400>  1851
ggccttgcta ttttggaagc tacaagaaaa aaatagagga aggaaggttt ggtcttttta       60

gtggacatgg ctcagatatc tagcaacagc ggatttaaag aatgtccatc ttcacatccg      120

gaaccaacaa gagcaaaaga tgtggacaaa gaagaagcat tacagatgga agcagaggct      180

ttagcaaaac tgcaaaagga tagacaagtg actgacaatc agagaggctt tgagttgtca      240

agcagcacca gaaaaaaagc acaggtttat aacaagcagg attatgatct catggtgttt      300

cctgaatcag attcccaaaa aagagcatta gatattgatg tagaaaagct cacccaagct      360

gaacttgaga aactattgct ggatgacagt ttcgagacta aaaaaacacc tgtattacca      420

gttactccta ttctgagccc ttccttttca gcacagctct attttagacc tactattcag      480

agaggacagt ggccacctgg attacctggg ccttccactt atgctttacc ttctatttat      540

ccttctactt acagtaaaca ggctgcattc caaaatggct tcaatccaag aatgcccact      600

tttccatcta cagaacctat atatttaagt cttccgggac aatctccata tttctcatat      660

cctttgacac ctgccacacc ctttcatcca caaggaagct tacctatcta tcgtccagta      720

gtcagtactg acatggcaaa actatttgac aaaatagcta gtacatcaga atttttaaaa      780

aatgggaaag caaggactga tttggagata acagattcaa aagtcagcaa tctacaggta      840

tctccaaagt ctgaggatat cagtaaattt gactggttag acttggatcc tctaagtaag      900

cctaaggtgg ataatgtgga ggtattagac catgaggaag agaaaaatgt ttcaagtttg      960

ctagcaaagg atccttggga tgctgttctt cttgaagaga gatcgacagc aaattgtcat     1020

cttgaaagaa aggtgaatgg aaaatccctt tctgtggcaa ctgttacaag aagccagtct     1080

ttaaatattc gaacaactca gcttgcaaaa gcccagggcc atatatctca gaaagaccca     1140

aatgggacca gtagtttgcc aactggaagt tctcttcttc aagaagttga agtacagaat     1200

gaggagatgg cagctttttg tcgatccatt acaaaattga agaccaaatt tccatatacc     1260

aatcaccgca caaacccagg ctatttgtta agtccagtca cagcacaaag aaacatatgc     1320

ggagaaaatg ctagtgtgaa ggtctccatt gacattgaag gatttcagct accagttact     1380

tttacgtgtg atgtgagttc tactgtagaa atcattataa tgcaagccct ttgctgggta     1440

catgatgact tgaatcaagt agatgttggc agctatgttc taaaagtttg tggtcaagag     1500

gaagtgctgc agaataatca ttgccttgga agtcatgagc atattcaaaa ctgtcgaaaa     1560

tgggacacag aaattagact acaactcttg accttcagtg caatgtgtca aaatctggcc     1620

cgaacagcag aagatgatga aacacccgtg gatttaaaca aacacctgta tcaaatagaa     1680

aaaccttgca aagaagccat gacgagacac cctgttgaag aactcttaga ttcttatcac     1740

aaccaagtag aactggctct tcaaattgaa aaccaacacc gagcagtaga tcaagtaatt     1800

aaagctgtaa gaaaaatctg tagtgcttta gatggtgtcg agactcttgc cattacagaa     1860

tcagtaaaga agctaaagag agcagttaat cttccaagga gtaaaactgc tgatgtgact     1920

tctttgtttg gaggagaaga cactagcagg agttcaacta ggggctcact taatcctgaa     1980

aatcctgttc aagtaagcat aaaccaatta actgcagcaa tttatgatct tctcagactc     2040

catgcaaatt ctggtaggag tcctacagac tgtgcccaaa gtagcaagag tgtcaaggaa     2100

gcatggacta caacagagca gctccagttt actatttttg ctgctcatgg aatttcaagt     2160

aattgggtat caaattatga aaaatactac ttgatatgtt cactgtctca caatggaaag     2220

gatcttttta aacctattca atcaaagaag gttggcactt acaagaattt cttctatctt     2280

attaaatggg atgaactaat catttttcct atccagatat cacaattgcc attagaatca     2340

gttcttcacc ttactctttt tggaatttta aatcagagca gtggaagttc ccctgattct     2400

aataagcaga gaaagggacc agaagctttg ggcaaagttt ctttacctct ttttgacttt     2460

aaacggtttt taacatgtgg aactaaactt ctatatcttt ggacttcatc acatacaaat     2520

tctgttcctg gaacagttac caaaaaagga tatgtcatgg aaagaatagt gctacaggtt     2580

gattttcctt ctcctgcatt tgatattatt tatacaactc ctcaagttga cagaagcatt     2640

atacagcaac ataacttaga aacactagag aatgatataa aagggaaact tcttgatatt     2700

cttcataaag actcatcact tggactttct aaagaagata aagctttttt atgggagaaa     2760

cgttattatt gcttcaaaca cccaaattgt cttcctaaaa tattagcaag cgccccaaac     2820

tggaaatggg ttaatcttgc caaaacttac tcattgcttc accagtggcc tgcattgtac     2880

ccactaattg cattggaact tcttgattca aaatttgctg atcaggaagt aagatcccta     2940

gctgtgacct ggattgaggc cattagtgat gatgagctaa cagatcttct tccacagttt     3000

gtacaagctt tgaaatatga aatttacttg aatagttcat tagtgcaatt ccttttgtcc     3060

agggcattgg gaaatatcca gatagcacac aatttatatt ggcttctcaa agatgccctg     3120

catgatgtac agtttagtac ccgatacgaa catgttttgg gtgctctcct gtcagtagga     3180

ggaaaacgac ttagagaaga acttctaaaa cagacgaaac ttgtacagct tttaggagga     3240

gtagcagaaa aagtaaggca ggctagtgga tcagccagac aggttgttct ccaaagaagt     3300

atggaacgag tacagtcctt ttttcagaaa aataaatgcc gtctccctct caagccaagt     3360

ctagtggcaa aagaattaaa tattaagtcg tgttccttct tcagttctaa tgctgtcccc     3420

ctaaaagtca caatggtgaa tgctgaccct atgggagaag aaattaatgt catgtttaag     3480

gttggtgaag atcttcggca agatatgtta gctttacaga tgataaagat tatggataag     3540

atctggctta aagaaggact agatctgagg atggtaattt tcaaatgtct ctcaactggc     3600

agagatcgag gcatggtgga gctggttcct gcttccgata ccctcaggaa aatccaagtg     3660

gaatatggtg tgacaggatc ctttaaagat aaaccacttg cagagtggct aaggaaatac     3720

aatccctctg aagaagaata tgaaaaggct tcagagaact ttatctattc ctgtgctgga     3780

tgctgtgtag ccacctatgt tttaggcatc tgtgatcgac acaatgacaa tataatgctt     3840

cgaagcacgg gacacatgtt tcacattgac tttggaaagt ttttgggaca tgcacagatg     3900

tttggcagct tcaaaaggga tcgggctcct tttgtgctga cctctgatat ggcatatgtc     3960

attaatgggg gtgaaaagcc caccattcgt tttcagttgt ttgtggacct ctgctgtcag     4020

gcctacaact tgataagaaa gcagacaaac ctttttctta acctcctttc actgatgatt     4080

ccttcagggt taccagaact tacaagtatt caagatttga aatacgttag agatgcactt     4140

caaccccaaa ctacagacgc agaagctaca attttcttta ctaggcttat tgaatcaagt     4200

ttgggaagca ttgccacaaa gtttaacttc ttcattcaca accttgctca gcttcgtttt     4260

tctggtcttc cttctaatga tgagcccatc ctttcatttt cacctaaaac atactccttt     4320

agacaagatg gtcgaatcaa ggaagtctct gtttttacat atcataagaa atacaaccca     4380

gataaacatt atatttatgt agtccgaatt ttgagggaag gacagattga accatcattt     4440

gtcttccgaa catttgacga atttcaggaa cttcacaata agctcagtat tatttttcca     4500

ctttggaagt taccaggctt tcctaatagg atggttctag gaagaacaca cataaaagat     4560

gtagcagcca aaaggaaaat tgagttaaac agttacttac agagtttgat gaatgcttca     4620

acggatgtag cagagtgtga tcttgtttgt actttcttcc accctttact tcgtgatgag     4680

aaagctgaag ggatagctag gtctgcagat gcaggttcct tcagtcctac tccaggccaa     4740

ataggaggag ctgtgaaatt atccatctct taccgaaatg gtactctttt catcatggtg     4800

atgcatatca aagatcttgt tactgaagat ggagctgacc caaatccata tgtcaaaaca     4860

tacctacttc cagataacca caaaacatcc aaacgtaaaa ccaaaatttc acgaaaaacg     4920

aggaatccga cattcaatga aatgcttgta tacagtggat atagcaaaga aaccctaaga     4980

cagcgagaac ttcaactaag tgtactcagt gcagaatctc tgcgggagaa ttttttcttg     5040

ggtggagtaa ccctgccttt gaaagatttc aacttgagca aagagacggt taaatggtat     5100

cagctgactg cggcaacata cttgtaaact agtgaatgtt tgagctttgg aagcatgaac     5160

agttataaac gtgcatgcat acatgcacac acacacagac acacacacac acacttgtta     5220

attttgtata gtatttttat acttggacag aacttataaa gttaaatata cttgctgcat     5280

ttcaacacat ctgttggacc aacagtcaca taactaacct ttttgaattt ttggaagcca     5340

ttgctgtttt aaagtcatta tgtagaatgc tacaaaccct aaacttaata tatactaatt     5400

cctgaaaaag actttgagac agtactatgt cagttcagcc acctattttg cattgttttc     5460

tataaggagg caaagcatat gtgttttcct gttatgcacc ttttatagcc tttaccactg     5520

tgtaatgttc acaaacacca aagtaaagga aaaatgcagg atgttaccgt aaaatccagc     5580

tgctattcat ggagctgaaa aacaaagcac aaataataga tagctaagtt aagaactact     5640

aagtagttta tagaagtagg gaaaaacgta atactgcttt ttattcatgt ctttaaagcc     5700

tttttcagaa taagtgccaa tcactgatgt tgtaaataat ggtgccttaa ctttatatgc     5760

ttccctggca cttcgtttct gatttttttc ctgatttgat aaataattag tacatagttt     5820

tcactcactt gcagcttact aaagacaaga aattatgtac atgtactaat gtttttccca     5880

caaaaaaatc ctttacttct gatgtatgaa ttagttatct aaatagttaa gcctaatacc     5940

tgaataagac tcaccaatgt gattgtacaa taaattctat cattccatta aaatcctaca     6000

tttattccca ggaatggtaa tttcacctcc ctacatctat actccactcc ctcagtaaat     6060

aagtgaaaat tgttaaccca tgtgcccatt cctgagtagg gcagactctt cacaagaggc     6120

ccatgacaag aattctaggg tccagattga actttaatat agacctttgt ctgtgtagac     6180

cagtttgtct tgtaaactgt cttacttatg tgtgtaaaca ttttacattc acatgaaaag     6240

ttattttcct ttatataatt ggattcagaa tcataaggga caggactgaa attattctac     6300

agtaaccagt aagaataaga ttcggccggg cacggtggct cctgcctgta atcccaacac     6360

tttgggaggc caaggtgggc ggatcacctg aggtcaggag tttgagacca gcctggccaa     6420

catggtgaaa ccccgtctct acacaaaaat tagccaggcg tggtagcggg catctgtaat     6480

cccagctact tggggggctg aggcaggaga atcgcttgaa cccaggaggc ggaggttgca     6540

gtgagccgag atcacgccac tgcactcccg cctgggtgac aagagcaaaa ctccatctta     6600

aaaaaaaaga aaaaaagagt aagattcatt tttattagtt actcaacttc agacacaatt     6660

ttgttaattt ggatatatac atatatataa taagaactca tggttagaat agaaatacag     6720

atactttaaa aatggtaata gaaattgtac caatcaggtt gctgtgagaa aactgacaaa     6780

atatgcaata aagaatacca agagagaaag gacaatcgcc aattcagttt cccagaacag     6840

aatttttatg aactgcacaa atgtttaatg taaatggtga tacctacagg gaagaaatag     6900

aagagttgat aatatatcac tgggacgggg tgggggaaag acttgaaatt tttggtgcct     6960

aacactaatg gtccatatgt agttaaaccc atgagtatgg tatatgaatg tcttttttaa     7020

atgttaaaat gtgttgtcta tttaatgtta attaaaatgc agatcaaagc accaccattt     7080

gctttttcca cagatcatta acatttcctt aaagtatgta agtacctttg caaatgcaaa     7140

tgtactagta attttcactt aagcttttga gaccgaattc cattccacca gttatcactt     7200

agccactgta atttaaaaac aaacaaacaa acaaaaactg tcttggtaga ggtcgttaat     7260

tagactcaac atgtactgcc tttttgcagt ctattatgac agtgtctttt agcacaaata     7320

atagagctaa aaaatgtcct gtcacttcca ttataagaaa tctggattca tatctaagtg     7380

tatattataa tactgtacag ttaagagttc agaacaagtg gtaatgtttt ctcttaattt     7440

aactcatttt gtgccttctt tactcattca aacacacata cattttacat atagtttatt     7500

tctttatgaa atgctaatct tcagcccgta ccaaaaagta gagtggagcc tctttgcact     7560

actactatca ataaatttta aatcagttgg atttttaagc attttttaaa agctgacatt     7620

aaagtaaatc taaaaaaagt ttaacaaact ggccaagaca ctaattttta tgtataatca     7680

caatatttta tactcacctt tattgactaa aaataattat gctacatgtt gtcctgcatc     7740

agaagaatta tttcttcttg ccagtgtttt gggatttgaa gataatggtt cactcaaaga     7800

acctattatt ttctctactg aggaacccaa tgtagaactt gcactgatat ttttattact     7860

gcctttatat gaatctatag gtatctaaat gttaaggcat gtatgatctt tgatcatttc     7920

ttttttcaaa ttaaagttgt ataaaagttt caatatcttg ccttaaatta gttgcctatt     7980

ctttctagga ttcaaatatt gtgacattta aaaaagaaaa cattcacttt tgaaacttag     8040

acttcagatc aaaaaggact gaacccccac tatcataatc catacattca tttccatgtt     8100

gtttgactag cagtgcatat atgaatgaat atggtaatta atcttaccta taagaaccaa     8160

atactttaat tatattaaga tagtgaataa agatgtataa tatttttatt aataccttga     8220

atatattcag tggattgaat gtgacttcat aactgtacta cgattgtatt aaaatatttc     8280

tggaataaaa aaaaaaaaaa aaaa                                            8304


<210>  1852
<211>  2168
<212>  DNA
<213>  homo sapiens

<400>  1852
tctggcgagg aagtaggccg ggctcaggcg ccttagccag agggcgggcc tgcgccaccc       60

tcggaaagcg tcacttccac ttccggccgg cgctctggct ctgtacctgg acagggctgc      120

ggtaggccag cggtgggctg gcggttgcgc tcctcagatc ggcggccttt cgggcggtgg      180

cttgcgtttg agcctcagaa agcgaggagc ggcctccacg gaagccaagc tggccgaggt      240

tgcagtccat gagctgggaa aggaggcagt gctcttggga gaaacagcag aggcctcaag      300

tttcgggctg aagccaacag agtcccaacc agtgggcgta tcccaagatg aagaattttg      360

gaatacatac gagggtctgc aagaacagct cagcaggaat actcataaag agactgagcc      420

tgtgtatgag agggctgtgc ctactcaaca gattctagct tttcctgagc aaacaaacac      480

caaagactgg acagtgacac ctgagcacgt cttgcctgag tcccagagct tgttgacatt      540

tgaagaagtg gccatgtatt tttcccagga agaatgggag ttattggatc ccactcagaa      600

ggccctctac aatgatgtaa tgcaggaaaa ctatgagact gtcatctctc tagcattgtt      660

tgtgctcccc aaacctaaag tgatctcctg tctagagcaa ggggaagagc catgggttca      720

agtatccccg gagtttaagg atagtgccgg aaaatctcct acagggttaa agctcaaaaa      780

cgacactgaa aatcatcagc ctgtgtctct ttctgactta gaaatacaag catcagcagg      840

cgtcatatca aaaaaggcca aagtaaaagt tccccagaaa acagcaggca aagaaaatca      900

ttttgatatg cacagagtgg gaaaatggca ccaagatttt ccagtgaaga aaagaaagaa      960

actttcaacc tggaaacaag agctgctcaa acttatggat cgtcacaaga aagattgtgc     1020

aagagagaag ccttttaaat gtcaggaatg tgggaaaacc ttcagagtta gctctgacct     1080

tattaagcac caaagaattc acactgaaga gaaaccctat aaatgtcaac agtgtgataa     1140

gaggtttaga tggagttcag atcttaataa gcacttaaca acacaccaag gaataaaacc     1200

atataaatgt tcatggtgtg ggaaaagctt cagtcaaaat acaaatttac atacacacca     1260

aagaactcat acaggagaaa agcccttcac atgtcatgaa tgtggaaaaa aattcagtca     1320

gaactcccac cttattaaac accggagaac ccacacaggt gagcagccat atacttgtag     1380

catatgcagg agaaacttca gcaggcggtc aagccttctt agacaccaga aactccacct     1440

gtgaagagaa gcttgtccag tgtcctcatt ctgaagacat tcaccaaatg gagcttggca     1500

ctaaaattta tgtaaaagaa aaatcacaaa ccttgaaaaa ttttacatca gaaaatggga     1560

taaacataca tttcacagaa aataatcaag acttgctctg cagccactca gtagtcttct     1620

gtggtcacag aagtaaacat tgttggcttt gtattgatct ctccagtcat ttttgaacac     1680

atccaataga aacattggca gcatggtctt ccaaaacaaa aagcagtaac atgcatgttt     1740

aattgcatac cattctcttc acagtagcag gcttaccaat ttccatagtc tcatgaggcc     1800

gaaatgaatt acaatgtaaa gtgttccagg aaccaaattg gattttcttt cttttgtcat     1860

tggacacggt ttgcaaagtt ggacatcact tgagttcctt cttaaacttt tcggcaactt     1920

ctcttggatc ctgttatcac agttttttac tgtgatgaaa tcttgttaac caccactagg     1980

gaatctccag atgaactatt aatgcactgt cttatgcctc tcattggtga tgtttggaaa     2040

atagaagaca tctctaatgg aatcatgggg gaaacgggtt ggaatttgta gccatggaat     2100

atatattaga tgtaaagaat tttctgcaat aaaagaaact agacttgtta aaaaaaaaaa     2160

aaaaaaaa                                                              2168


<210>  1853
<211>  5533
<212>  DNA
<213>  homo sapiens

<400>  1853
gattgccatc tgacaagatc tccaaatcaa agtgataaat cgctccaaac tttttttggc       60

ggcgctgaga tgttggaggg gcgtctagcg cgcatgtgcg aaggtgtcca aactgacaat      120

gctggagaga tagcgagtgt ggattgagag aaagggagag agggagggag agagagtgaa      180

agaagaaaat acagagagtg agtgtgtgga agagagagag aaacaggaga gaaacaggag      240

ggagggagag agagagagag agagagagag agagagagag agagagagag agagagagag      300

acaggagaga gagggaggga gcgagaggga gagcaaaaga aggaaaggat ccaagaaaaa      360

aaagccccaa ccacacacca gcggctgcag gactgggcac agcatgagat ccaaaggcag      420

ggcaaggaaa ctggccacaa ataatgagtg tgtatatggc aactaccctg aaataccttt      480

ggaagaaatg ccagatgcag atggagtagc cagcactccc tccctcaata ttcaagagcc      540

atgctctcct gccacatcca gtgaagcatt cactccaaag gagggttctc cttacaaagc      600

ccccatctac atccctgatg atatccccat tcctgctgag tttgaacttc gagagtcaaa      660

tatgcctggg gcaggactag gaatatggac caaaaggaag atcgaagtag gtgaaaagtt      720

tgggccttat gtgggagagc agaggtcaaa cctgaaagac cccagttatg gatgggagat      780

cttagacgaa ttttacaatg tgaagttctg catagatgcc agtcaaccag atgttggaag      840

ctggctcaag tacattagat tcgctggctg ttatgatcag cacaaccttg ttgcatgcca      900

gataaatgat cagatattct atagagtagt tgcagacatt gcgccgggag aggagcttct      960

gctgttcatg aagagcgaag actatcccca tgaaactatg gcgccggata tccacgaaga     1020

acggcaatat cgctgcgaag actgtgacca gctctttgaa tctaaggctg aactagcaga     1080

tcaccaaaag tttccatgca gtactcctca ctcagcattt tcaatggttg aagaggactt     1140

tcagcaaaaa ctcgaaagcg agaatgatct ccaagagata cacacgatcc aggagtgtaa     1200

ggaatgtgac caagtttttc ctgatttgca aagcctggag aaacacatgc tgtcacatac     1260

tgaagagagg gaatacaagt gtgatcagtg tcccaaggca tttaactgga agtccaattt     1320

aattcgccac cagatgtcac atgacagtgg aaagcactat gaatgtgaaa actgtgccaa     1380

ggttttcacg gaccctagca accttcagcg gcacattcgc tctcagcatg tcggtgcccg     1440

ggcccatgca tgcccggagt gtggcaaaac gtttgccact tcgtcgggcc tcaaacaaca     1500

caagcacatc cacagcagtg tgaagccctt tatctgtgag gtctgccata aatcctatac     1560

tcagttttca aacctttgcc gtcataagcg catgcatgct gattgcagaa cccaaatcaa     1620

gtgcaaagac tgtggacaaa tgttcagcac tacgtcttcc ttaaataaac acaggaggtt     1680

ttgtgagggc aagaaccatt ttgcggcagg tggatttttt ggccaaggca tttcacttcc     1740

tggaacccca gctatggata aaacgtccat ggttaatatg agtcatgcca acccgggcct     1800

tgctgactat tttggcgcca ataggcatcc tgctggtctt acctttccaa cagctcctgg     1860

attttctttt agcttccctg gtctgtttcc ttccggcttg taccacaggc ctcctttgat     1920

acctgctagt tctcctgtta aaggactatc aagtactgaa cagacaaaca aaagtcaaag     1980

tcccctcatg acacatcctc agatactgcc agctacacag gatattttga aggcactatc     2040

taaacaccca tctgtagggg acaataagcc agtggagctc cagcccgaga ggtcctctga     2100

agagaggccc tttgagaaaa tcagtgacca gtcagagagt agtgaccttg atgatgtcag     2160

tacaccaagt ggcagtgacc tggaaacaac ctcgggctct gatctggaaa gtgacattga     2220

aagtgataaa gagaaattta aagaaaatgg taaaatgttc aaagacaaag taagccctct     2280

tcagaatctg gcttcaataa ataataagaa agaatacagc aatcattcca ttttctcacc     2340

atctttagag gagcagactg cggtgtcagg agctgtgaat gattctataa aggctattgc     2400

ttctattgct gaaaaatact ttggttcaac aggactggtg gggctgcaag acaaaaaagt     2460

tggagcttta ccttaccctt ccatgtttcc cctcccattt tttccagcat tctctcaatc     2520

aatgtaccca tttcctgata gagacttgag atcgttacct ttgaaaatgg aaccccaatc     2580

accaggtgaa gtaaagaaac tgcagaaggg cagctctgag tccccctttg atctcaccac     2640

taagcgaaag gatgagaagc ccttgactcc agtcccctcc aagcctccag tgacacctgc     2700

cacaagccaa gaccagcccc tggatctaag tatgggcagt aggagtagag ccagtgggac     2760

aaagctgact gagcctcgaa aaaaccacgt gtttggggga aaaaaaggaa gcaacgtcga     2820

atcaagacct gcttcagatg gttccttgca gcatgcaaga cccactcctt tctttatgga     2880

ccctatttac agagtagaga aaagaaaact aactgaccca cttgaagctt taaaagagaa     2940

atacttgagg ccttctccag gattcttgtt tcacccacaa ttccaactgc ctgatcagag     3000

aacttggatg tcagctattg aaaacatggc agaaaagcta gagagcttca gtgccctgaa     3060

acctgaggcc agtgagctct tacagtcagt gccctctatg ttcaacttca gggcgcctcc     3120

caatgccctg ccagagaacc ttctgcggaa gggaaaggag cgctatacct gcagatactg     3180

tggcaagatt tttccaaggt ctgcaaacct aacacggcac ttgagaaccc acacaggaga     3240

gcagccttac agatgcaaat actgtgacag atcatttagc atatcttcta acttgcaaag     3300

gcatgttcgc aacatccaca ataaagagaa gccatttaag tgtcacttat gtgataggtg     3360

ttttggtcaa caaaccaatt tagacagaca cctaaagaaa catgagaatg ggaacatgtc     3420

cggtacagca acatcgtcgc ctcattctga actggaaagt acaggtgcga ttctggatga     3480

caaagaagat gcttacttca cagaaattcg aaatttcatt gggaacagca accatggcag     3540

ccaatctccc aggaatgtgg aggagagaat gaatggcagt cattttaaag atgaaaaggc     3600

tttggtgacc agtcaaaatt cagacttgct ggatgatgaa gaagttgaag atgaggtgtt     3660

gttagatgag gaggatgaag acaatgatat tactggaaaa acaggaaagg aaccagtgac     3720

aagtaattta catgaaggaa accctgagga tgactatgaa gaaaccagtg ccctggagat     3780

gagttgcaag acatccccag tgaggtataa agaggaagaa tataaaagtg gactttctgc     3840

tctagatcat ataaggcact tcacagatag cctcaaaatg aggaaaatgg aagataatca     3900

atattctgaa gctgagctgt cttcttttag tacttcccat gtgccagagg aacttaagca     3960

gccgttacac agaaagtcca aatcgcaggc atatgctatg atgctgtcac tgtctgacaa     4020

ggagtccctc cattctacat cccacagttc ttccaacgtg tggcacagta tggccagggc     4080

tgcggcggaa tccagtgcta tccagtccat aagccacgta tgacgttatc aaggttgacc     4140

agagtgggac caagtccaac agtagcatgg ctctttcata taggactatt tacaagactg     4200

ctgagcagaa tgccttataa acctgcaggg tcactcatct aaagtctagt gaccttaaac     4260

tgaatgattt aaaaaagaaa agaaagaaaa aagaaactat ttattctcga tattttgttt     4320

tgcacagcaa aggcagctgc tgacttctgg aagatcaatc aatgcgactt aaagtgattc     4380

agtgaaaaca aaaaacttgg tgggctgaag gcatcttcca gtttacccca ccttagggta     4440

tgggtgggtg agaagggcag ttgagatggc agcattgata tgaatgaaca ctccatagaa     4500

actgaattct cttttgtaca agatcacctg acatgattgg gaacagttgc ttttaattac     4560

agatttaatt tttttcttcg ttaaagtttt atgtaattta accctttgaa gacagaagta     4620

gttggatgaa atgcacagtc aattattata gaaactgata acagggagta cttgttcccc     4680

cttttgcctt cttaagtaca ttgtttaaaa ctagggaaaa agggtatgtg tatattgtaa     4740

actatggatg ttaacactca aagaggttaa gtcagtgaag taacctattc atcaccagta     4800

ccgctgtacc actaataaat tgtttgccaa atccttgtaa taacatctta attttagaca     4860

atcatgtcac tgtttttaat gtttattttt ttgtgtgtgt tgcgtgtatc atgtatttat     4920

ttgttggcaa actattgttt gttgattaaa atagcactgt tccagtcagc cactacttta     4980

tgacgtctga ggcacacccc tttccgaatt tcaaggacca aggtgacccg acctgtgtat     5040

gagagtgcca aatggtgttt ggcttttctt aacattcctt tttgtttgtt tgttttgttt     5100

tccttcttaa tgaactaaat acgaatagat gcaacttagt ttttgtaata ctgaaatcga     5160

ttcaattgta taaacgatta taatttcttt catggaagca tgattcttct gattaaaaac     5220

tgtactccat attttatgct ggttgtctgc aagcttgtgc gatgttatgt tcatgttaat     5280

cctatttgta aaatgaagtg ttcccaacct tatgttaaaa gagagaagta aataacagac     5340

tgtattcagt tattttgccc tttattgagg aaccagattt gttttctttt tgtttgtaat     5400

ctcattttga aataatcagc aagttgaggt actttcttca aatgctttgt acaatataaa     5460

ctgttatgcc tttcagtgca ttactatggg aggagcaact aaaaaataaa gacttacaaa     5520

aaggagtatt ttt                                                        5533


<210>  1854
<211>  10241
<212>  DNA
<213>  homo sapiens

<400>  1854
ccggcgtcgg cggcgcgcgc gctccctcct ctcggagaga gggctgtggt aaaagccgtc       60

cggaaaatgg ccgccgccgc cgccgccgcg ccgagcggag gaggaggagg aggcgaggag      120

gagagactgc tccataaaaa tacagactca ccagttcctg ctttgatgtg acatgtgact      180

ccccagaata caccttgctt ctgtagacca gctccaacag gattccatgg tagctgggat      240

gttagggctc agggaagaaa agtcagaaga ccaggacctc cagggcctca aggacaaacc      300

cctcaagttt aaaaaggtga agaaagataa gaaagaagag aaagagggca agcatgagcc      360

cgtgcagcca tcagcccacc actctgctga gcccgcagag gcaggcaaag cagagacatc      420

agaagggtca ggctccgccc cggctgtgcc ggaagcttct gcctccccca aacagcggcg      480

ctccatcatc cgtgaccggg gacccatgta tgatgacccc accctgcctg aaggctggac      540

acggaagctt aagcaaagga aatctggccg ctctgctggg aagtatgatg tgtatttgat      600

caatccccag ggaaaagcct ttcgctctaa agtggagttg attgcgtact tcgaaaaggt      660

aggcgacaca tccctggacc ctaatgattt tgacttcacg gtaactggga gagggagccc      720

ctcccggcga gagcagaaac cacctaagaa gcccaaatct cccaaagctc caggaactgg      780

cagaggccgg ggacgcccca aagggagcgg caccacgaga cccaaggcgg ccacgtcaga      840

gggtgtgcag gtgaaaaggg tcctggagaa aagtcctggg aagctccttg tcaagatgcc      900

ttttcaaact tcgccagggg gcaaggctga ggggggtggg gccaccacat ccacccaggt      960

catggtgatc aaacgccccg gcaggaagcg aaaagctgag gccgaccctc aggccattcc     1020

caagaaacgg ggccgaaagc cggggagtgt ggtggcagcc gctgccgccg aggccaaaaa     1080

gaaagccgtg aaggagtctt ctatccgatc tgtgcaggag accgtactcc ccatcaagaa     1140

gcgcaagacc cgggagacgg tcagcatcga ggtcaaggaa gtggtgaagc ccctgctggt     1200

gtccaccctc ggtgagaaga gcgggaaagg actgaagacc tgtaagagcc ctgggcggaa     1260

aagcaaggag agcagcccca aggggcgcag cagcagcgcc tcctcacccc ccaagaagga     1320

gcaccaccac catcaccacc actcagagtc cccaaaggcc cccgtgccac tgctcccacc     1380

cctgccccca cctccacctg agcccgagag ctccgaggac cccaccagcc cccctgagcc     1440

ccaggacttg agcagcagcg tctgcaaaga ggagaagatg cccagaggag gctcactgga     1500

gagcgacggc tgccccaagg agccagctaa gactcagccc gcggttgcca ccgccgccac     1560

ggccgcagaa aagtacaaac accgagggga gggagagcgc aaagacattg tttcatcctc     1620

catgccaagg ccaaacagag aggagcctgt ggacagccgg acgcccgtga ccgagagagt     1680

tagctgactt tacacggagc ggattgcaaa gcaaaccaac aagaataaag gcagctgttg     1740

tctcttctcc ttatgggtag ggctctgaca aagcttcccg attaactgaa ataaaaaata     1800

tttttttttc tttcagtaaa cttagagttt cgtggcttca gggtgggagt agttggagca     1860

ttggggatgt ttttcttacc gacaagcaca gtcaggttga agacctaacc agggccagaa     1920

gtagctttgc acttttctaa actaggctcc ttcaacaagg cttgctgcag atactactga     1980

ccagacaagc tgttgaccag gcacctcccc tcccgcccaa acctttcccc catgtggtcg     2040

ttagagacag agcgacagag cagttgagag gacactcccg ttttcggtgc catcagtgcc     2100

ccgtctacag ctcccccagc tccccccacc tcccccactc ccaaccacgt tgggacaggg     2160

aggtgtgagg caggagagac agttggattc tttagagaag atggatatga ccagtggcta     2220

tggcctgtgc gatcccaccc gtggtggctc aagtctggcc ccacaccagc cccaatccaa     2280

aactggcaag gacgcttcac aggacaggaa agtggcacct gtctgctcca gctctggcat     2340

ggctaggagg ggggagtccc ttgaactact gggtgtagac tggcctgaac cacaggagag     2400

gatggcccag ggtgaggtgg catggtccat tctcaaggga cgtcctccaa cgggtggcgc     2460

tagaggccat ggaggcagta ggacaaggtg caggcaggct ggcctggggt caggccgggc     2520

agagcacagc ggggtgagag ggattcctaa tcactcagag cagtctgtga cttagtggac     2580

aggggagggg gcaaaggggg aggagaagaa aatgttcttc cagttacttt ccaattctcc     2640

tttagggaca gcttagaatt atttgcacta ttgagtcttc atgttcccac ttcaaaacaa     2700

acagatgctc tgagagcaaa ctggcttgaa ttggtgacat ttagtccctc aagccaccag     2760

atgtgacagt gttgagaact acctggattt gtatatatac ctgcgcttgt tttaaagtgg     2820

gctcagcaca tagggttccc acgaagctcc gaaactctaa gtgtttgctg caattttata     2880

aggacttcct gattggtttc tcttctcccc ttccatttct gccttttgtt catttcatcc     2940

tttcacttct ttcccttcct ccgtcctcct ccttcctagt tcatcccttc tcttccaggc     3000

agccgcggtg cccaaccaca cttgtcggct ccagtcccca gaactctgcc tgccctttgt     3060

cctcctgctg ccagtaccag ccccaccctg ttttgagccc tgaggaggcc ttgggctctg     3120

ctgagtccga cctggcctgt ctgtgaagag caagagagca gcaaggtctt gctctcctag     3180

gtagccccct cttccctggt aagaaaaagc aaaaggcatt tcccaccctg aacaacgagc     3240

cttttcaccc ttctactcta gagaagtgga ctggaggagc tgggcccgat ttggtagttg     3300

aggaaagcac agaggcctcc tgtggcctgc cagtcatcga gtggcccaac aggggctcca     3360

tgccagccga ccttgacctc actcagaagt ccagagtcta gcgtagtgca gcagggcagt     3420

agcggtacca atgcagaact cccaagaccc gagctgggac cagtacctgg gtccccagcc     3480

cttcctctgc tccccctttt ccctcggagt tcttcttgaa tggcaatgtt ttgcttttgc     3540

tcgatgcaga cagggggcca gaacaccaca catttcactg tctgtctggt ccatagctgt     3600

ggtgtagggg cttagaggca tgggcttgct gtgggttttt aattgatcag ttttcatgtg     3660

ggatcccatc tttttaacct ctgttcagga agtccttatc tagctgcata tcttcatcat     3720

attggtatat ccttttctgt gtttacagag atgtctctta tatctaaatc tgtccaactg     3780

agaagtacct tatcaaagta gcaaatgaga cagcagtctt atgcttccag aaacacccac     3840

aggcatgtcc catgtgagct gctgccatga actgtcaagt gtgtgttgtc ttgtgtattt     3900

cagttattgt ccctggcttc cttactatgg tgtaatcatg aaggagtgaa acatcataga     3960

aactgtctag cacttccttg ccagtcttta gtgatcagga accatagttg acagttccaa     4020

tcagtagctt aagaaaaaac cgtgtttgtc tcttctggaa tggttagaag tgagggagtt     4080

tgccccgttc tgtttgtaga gtctcatagt tggactttct agcatatatg tgtccatttc     4140

cttatgctgt aaaagcaagt cctgcaacca aactcccatc agcccaatcc ctgatccctg     4200

atcccttcca cctgctctgc tgatgacccc cccagcttca cttctgactc ttccccagga     4260

agggaagggg ggtcagaaga gagggtgagt cctccagaac tcttcctcca aggacagaag     4320

gctcctgccc ccatagtggc ctcgaactcc tggcactacc aaaggacact tatccacgag     4380

agcgcagcat ccgaccaggt tgtcactgag aagatgttta ttttggtcag ttgggttttt     4440

atgtattata cttagtcaaa tgtaatgtgg cttctggaat cattgtccag agctgcttcc     4500

ccgtcacctg ggcgtcatct ggtcctggta agaggagtgc gtggcccacc aggcccccct     4560

gtcacccatg acagttcatt cagggccgat ggggcagtcg tggttgggaa cacagcattt     4620

caagcgtcac tttatttcat tcgggcccca cctgcagctc cctcaaagag gcagttgccc     4680

agcctctttc ccttccagtt tattccagag ctgccagtgg ggcctgaggc tccttagggt     4740

tttctctcta tttccccctt tcttcctcat tccctcgtct ttcccaaagg catcacgagt     4800

cagtcgcctt tcagcaggca gccttggcgg tttatcgccc tggcaggcag gggccctgca     4860

gctctcatgc tgcccctgcc ttggggtcag gttgacagga ggttggaggg aaagccttaa     4920

gctgcaggat tctcaccagc tgtgtccggc ccagttttgg ggtgtgacct caatttcaat     4980

tttgtctgta cttgaacatt atgaagatgg gggcctcttt cagtgaattt gtgaacagca     5040

gaattgaccg acagctttcc agtacccatg gggctaggtc attaaggcca catccacagt     5100

ctcccccacc cttgttccag ttgttagtta ctacctcctc tcctgacaat actgtatgtc     5160

gtcgagctcc ccccaggtct acccctcccg gccctgcctg ctggtgggct tgtcatagcc     5220

agtgggattg ccggtcttga cagctcagtg agctggagat acttggtcac agccaggcgc     5280

tagcacagct cccttctgtt gatgctgtat tcccatatca aaagacacag gggacaccca     5340

gaaacgccac atcccccaat ccatcagtgc caaactagcc aacggcccca gcttctcagc     5400

tcgctggatg gcggaagctg ctactcgtga gcgccagtgc gggtgcagac aatcttctgt     5460

tgggtggcat cattccaggc ccgaagcatg aacagtgcac ctgggacagg gagcagcccc     5520

aaattgtcac ctgcttctct gcccagcttt tcattgctgt gacagtgatg gcgaaagagg     5580

gtaataacca gacacaaact gccaagttgg gtggagaaag gagtttcttt agctgacaga     5640

atctctgaat tttaaatcac ttagtaagcg gctcaagccc aggagggagc agagggatac     5700

gagcggagtc ccctgcgcgg gaccatctgg aattggttta gcccaagtgg agcctgacag     5760

ccagaactct gtgtcccccg tctaaccaca gctccttttc cagagcattc cagtcaggct     5820

ctctgggctg actgggccag gggaggttac aggtaccagt tctttaagaa gatctttggg     5880

catatacatt tttagcctgt gtcattgccc caaatggatt cctgtttcaa gttcacacct     5940

gcagattcta ggacctgtgt cctagacttc agggagtcag ctgtttctag agttcctacc     6000

atggagtggg tctggaggac ctgcccggtg ggggggcaga gccctgctcc ctccgggtct     6060

tcctactctt ctctctgctc tgacgggatt tgttgattct ctccattttg gtgtctttct     6120

cttttagata ttgtatcaat ctttagaaaa ggcatagtct acttgttata aatcgttagg     6180

atactgcctc ccccagggtc taaaattaca tattagaggg gaaaagctga acactgaagt     6240

cagttctcaa caatttagaa ggaaaaccta gaaaacattt ggcagaaaat tacatttcga     6300

tgtttttgaa tgaatacgag caagctttta caacagtgct gatctaaaaa tacttagcac     6360

ttggcctgag atgcctggtg agcattacag gcaaggggaa tctggaggta gccgacctga     6420

ggacatggct tctgaacctg tcttttggga gtggtatgga aggtggagcg ttcaccagtg     6480

acctggaagg cccagcacca ccctccttcc cactcttctc atcttgacag agcctgcccc     6540

agcgctgacg tgtcaggaaa acacccaggg aactaggaag gcacttctgc ctgaggggca     6600

gcctgccttg cccactcctg ctctgctcgc ctcggatcag ctgagccttc tgagctggcc     6660

tctcactgcc tccccaaggc cccctgcctg ccctgtcagg aggcagaagg aagcaggtgt     6720

gagggcagtg caaggaggga gcacaacccc cagctcccgc tccgggctcc gacttgtgca     6780

caggcagagc ccagaccctg gaggaaatcc tacctttgaa ttcaagaaca tttggggaat     6840

ttggaaatct ctttgccccc aaacccccat tctgtcctac ctttaatcag gtcctgctca     6900

gcagtgagag cagatgaggt gaaaaggcca agaggtttgg ctcctgccca ctgatagccc     6960

ctctccccgc agtgtttgtg tgtcaagtgg caaagctgtt cttcctggtg accctgatta     7020

tatccagtaa cacatagact gtgcgcatag gcctgctttg tctcctctat cctgggcttt     7080

tgttttgctt tttagttttg cttttagttt ttctgtccct tttatttaac gcaccgacta     7140

gacacacaaa gcagttgaat ttttatatat atatctgtat attgcacaat tataaactca     7200

ttttgcttgt ggctccacac acacaaaaaa agacctgtta aaattatacc tgttgcttaa     7260

ttacaatatt tctgataacc atagcatagg acaagggaaa ataaaaaaag aaaaaaaaga     7320

aaaaaaaacg acaaatctgt ctgctggtca cttcttctgt ccaagcagat tcgtggtctt     7380

ttcctcgctt ctttcaaggg ctttcctgtg ccaggtgaag gaggctccag gcagcaccca     7440

ggttttgcac tcttgtttct cccgtgcttg tgaaagaggt cccaaggttc tgggtgcagg     7500

agcgctccct tgacctgctg aagtccggaa cgtagtcggc acagcctggt cgccttccac     7560

ctctgggagc tggagtccac tggggtggcc tgactccccc agtccccttc ccgtgacctg     7620

gtcagggtga gcccatgtgg agtcagcctc gcaggcctcc ctgccagtag ggtccgagtg     7680

tgtttcatcc ttcccactct gtcgagcctg ggggctggag cggagacggg aggcctggcc     7740

tgtctcggaa cctgtgagct gcaccaggta gaacgccagg gaccccagaa tcatgtgcgt     7800

cagtccaagg ggtcccctcc aggagtagtg aagactccag aaatgtccct ttcttctccc     7860

ccatcctacg agtaattgca tttgcttttg taattcttaa tgagcaatat ctgctagaga     7920

gtttagctgt aacagttctt tttgatcatc tttttttaat aattagaaac accaaaaaaa     7980

tccagaaact tgttcttcca aagcagagag cattataatc accagggcca aaagcttccc     8040

tccctgctgt cattgcttct tctgaggcct gaatccaaaa gaaaaacagc cataggccct     8100

ttcagtggcc gggctacccg tgagcccttc ggaggaccag ggctggggca gcctctgggc     8160

ccacatccgg ggccagctcc ggcgtgtgtt cagtgttagc agtgggtcat gatgctcttt     8220

cccacccagc ctgggatagg ggcagaggag gcgaggaggc cgttgccgct gatgtttggc     8280

cgtgaacagg tgggtgtctg cgtgcgtcca cgtgcgtgtt ttctgactga catgaaatcg     8340

acgcccgagt tagcctcacc cggtgacctc tagccctgcc cggatggagc ggggcccacc     8400

cggttcagtg tttctgggga gctggacagt ggagtgcaaa aggcttgcag aacttgaagc     8460

ctgctccttc ccttgctacc acggcctcct ttccgtttga tttgtcactg cttcaatcaa     8520

taacagccgc tccagagtca gtagtcaatg aatatatgac caaatatcac caggactgtt     8580

actcaatgtg tgccgagccc ttgcccatgc tgggctcccg tgtatctgga cactgtaacg     8640

tgtgctgtgt ttgctcccct tccccttcct tctttgccct ttacttgtct ttctggggtt     8700

tttctgtttg ggtttggttt ggtttttatt tctccttttg tgttccaaac atgaggttct     8760

ctctactggt cctcttaact gtggtgttga ggcttatatt tgtgtaattt ttggtgggtg     8820

aaaggaattt tgctaagtaa atctcttctg tgtttgaact gaagtctgta ttgtaactat     8880

gtttaaagta attgttccag agacaaatat ttctagacac tttttcttta caaacaaaag     8940

cattcggagg gagggggatg gtgactgaga tgagagggga gagctgaaca gatgacccct     9000

gcccagatca gccagaagcc acccaaagca gtggagccca ggagtcccac tccaagccag     9060

caagccgaat agctgatgtg ttgccacttt ccaagtcact gcaaaaccag gttttgttcc     9120

gcccagtgga ttcttgtttt gcttcccctc cccccgagat tattaccacc atcccgtgct     9180

tttaaggaaa ggcaagattg atgtttcctt gaggggagcc aggaggggat gtgtgtgtgc     9240

agagctgaag agctggggag aatggggctg ggcccaccca agcaggaggc tgggacgctc     9300

tgctgtgggc acaggtcagg ctaatgttgg cagatgcagc tcttcctgga caggccaggt     9360

ggtgggcatt ctctctccaa ggtgtgcccc gtgggcatta ctgtttaaga cacttccgtc     9420

acatcccacc ccatcctcca gggctcaaca ctgtgacatc tctattcccc accctcccct     9480

tcccagggca ataaaatgac catggagggg gcttgcactc tcttggctgt cacccgatcg     9540

ccagcaaaac ttagatgtga gaaaacccct tcccattcca tggcgaaaac atctccttag     9600

aaaagccatt accctcatta ggcatggttt tgggctccca aaacacctga cagcccctcc     9660

ctcctctgag aggcggagag tgctgactgt agtgaccatt gcatgccggg tgcagcatct     9720

ggaagagcta ggcagggtgt ctgccccctc ctgagttgaa gtcatgctcc cctgtgccag     9780

cccagaggcc gagagctatg gacagcattg ccagtaacac aggccaccct gtgcagaagg     9840

gagctggctc cagcctggaa acctgtctga ggttgggaga ggtgcacttg gggcacaggg     9900

agaggccggg acacacttag ctggagatgt ctctaaaagc cctgtatcgt attcaccttc     9960

agtttttgtg ttttgggaca attactttag aaaataagta ggtcgtttta aaaacaaaaa    10020

ttattgattg cttttttgta gtgttcagaa aaaaggttct ttgtgtatag ccaaatgact    10080

gaaagcactg atatatttaa aaacaaaagg caatttatta aggaaatttg taccatttca    10140

gtaaacctgt ctgaatgtac ctgtatacgt ttcaaaaaca cccccccccc actgaatccc    10200

tgtaacctat ttattatata aagagtttgc cttataaatt t                        10241


<210>  1855
<211>  8605
<212>  DNA
<213>  homo sapiens

<400>  1855
aattcgccaa ctgaaaaagt gggaaaggat gtctggaggc gaggcgtccc attacagagg       60

aaggagctcg ctatataagc cagccaaagt tggctgcacc ggccacagcc tgcctactgt      120

cacccgcctc tcccgcgcgc agatacacgc ccccgcctcc gtgggcacaa aggcagcgct      180

gctggggaac tcgggggaac gcgcacgtgg gaaccgccgc agctccacac tccaggtact      240

tcttccaagg acctaggtct ctcgcccatc ggaaagaaaa taattctttc aagaagatca      300

gggacaactg atttgaagtc tactctgtgc ttctaaatcc ccaattctgc tgaaagtgag      360

ataccctaga gccctagagc cccagcagca cccagccaaa cccacctcca ccatgggggc      420

catgactcag ctgttggcag gtgtctttct tgctttcctt gccctcgcta ccgaaggtgg      480

ggtcctcaag aaagtcatcc ggcacaagcg acagagtggg gtgaacgcca ccctgccaga      540

agagaaccag ccagtggtgt ttaaccacgt ttacaacatc aagctgccag tgggatccca      600

gtgttcggtg gatctggagt cagccagtgg ggagaaagac ctggcaccgc cttcagagcc      660

cagcgaaagc tttcaggagc acacagtgga tggggaaaac cagattgtct tcacacatcg      720

catcaacatc ccccgccggg cctgtggctg tgccgcagcc cctgatgtta aggagctgct      780

gagcagactg gaggagctgg agaacctggt gtcttccctg agggagcaat gtactgcagg      840

agcaggctgc tgtctccagc ctgccacagg ccgcttggac accaggccct tctgtagcgg      900

tcggggcaac ttcagcactg aaggatgtgg ctgtgtctgc gaacctggct ggaaaggccc      960

caactgctct gagcccgaat gtccaggcaa ctgtcacctt cgaggccggt gcattgatgg     1020

gcagtgcatc tgtgacgacg gcttcacggg cgaggactgc agccagctgg cttgccccag     1080

cgactgcaat gaccagggca agtgcgtaaa tggagtctgc atctgtttcg aaggctacgc     1140

cggggctgac tgcagccgtg aaatctgccc agtgccctgc agtgaggagc acggcacatg     1200

tgtagatggc ttgtgtgtgt gccacgatgg ctttgcaggc gatgactgca acaagcctct     1260

gtgtctcaac aattgctaca accgtggacg atgcgtggag aatgagtgcg tgtgtgatga     1320

gggtttcacg ggcgaagact gcagtgagct catctgcccc aatgactgct tcgaccgggg     1380

ccgctgcatc aatggcacct gctactgcga agaaggcttc acaggtgaag actgcgggaa     1440

acccacctgc ccacatgcct gccacaccca gggccggtgt gaggaggggc agtgtgtatg     1500

tgatgagggc tttgccggtg tggactgcag cgagaagagg tgtcctgctg actgtcacaa     1560

tcgtggccgc tgtgtagacg ggcggtgtga gtgtgatgat ggtttcactg gagctgactg     1620

tggggagctc aagtgtccca atggctgcag tggccatggc cgctgtgtca atgggcagtg     1680

tgtgtgtgat gagggctata ctggggagga ctgcagccag ctacggtgcc ccaatgactg     1740

tcacagtcgg ggccgctgtg tcgagggcaa atgtgtatgt gagcaaggct tcaagggcta     1800

tgactgcagt gacatgagct gccctaatga ctgtcaccag cacggccgct gtgtgaatgg     1860

catgtgtgtt tgtgatgacg gctacacagg ggaagactgc cgggatcgcc aatgccccag     1920

ggactgcagc aacaggggcc tctgtgtgga cggacagtgc gtctgtgagg acggcttcac     1980

cggccctgac tgtgcagaac tctcctgtcc aaatgactgc catggccagg gtcgctgtgt     2040

gaatgggcag tgcgtgtgcc atgaaggatt tatgggcaaa gactgcaagg agcaaagatg     2100

tcccagtgac tgtcatggcc agggccgctg cgtggacggc cagtgcatct gccacgaggg     2160

cttcacaggc ctggactgtg gccagcactc ctgccccagt gactgcaaca acttaggaca     2220

atgcgtctcg ggccgctgca tctgcaacga gggctacagc ggagaagact gctcagaggt     2280

gtctcctccc aaagacctcg ttgtgacaga agtgacggaa gagacggtca acctggcctg     2340

ggacaatgag atgcgggtca cagagtacct tgtcgtgtac acgcccaccc acgagggtgg     2400

tctggaaatg cagttccgtg tgcctgggga ccagacgtcc accatcatcc aggagctgga     2460

gcctggtgtg gagtacttta tccgtgtatt tgccatcctg gagaacaaga agagcattcc     2520

tgtcagcgcc agggtggcca cgtacttacc tgcacctgaa ggcctgaaat tcaagtccat     2580

caaggagaca tctgtggaag tggagtggga tcctctagac attgcttttg aaacctggga     2640

gatcatcttc cggaatatga ataaagaaga tgagggagag atcaccaaaa gcctgaggag     2700

gccagagacc tcttaccggc aaactggtct agctcctggg caagagtatg agatatctct     2760

gcacatagtg aaaaacaata cccggggccc tggcctgaag agggtgacca ccacacgctt     2820

ggatgccccc agccagatcg aggtgaaaga tgtcacagac accactgcct tgatcacctg     2880

gttcaagccc ctggctgaga tcgatggcat tgagctgacc tacggcatca aagacgtgcc     2940

aggagaccgt accaccatcg atctcacaga ggacgagaac cagtactcca tcgggaacct     3000

gaagcctgac actgagtacg aggtgtccct catctcccgc agaggtgaca tgtcaagcaa     3060

cccagccaaa gagaccttca caacaggcct cgatgctccc aggaatcttc gacgtgtttc     3120

ccagacagat aacagcatca ccctggaatg gaggaatggc aaggcagcta ttgacagtta     3180

cagaattaag tatgccccca tctctggagg ggaccacgct gaggttgatg ttccaaagag     3240

ccaacaagcc acaaccaaaa ccacactcac aggtctgagg ccgggaactg aatatgggat     3300

tggagtttct gctgtgaagg aagacaagga gagcaatcca gcgaccatca acgcagccac     3360

agagttggac acgcccaagg accttcaggt ttctgaaact gcagagacca gcctgaccct     3420

gctctggaag acaccgttgg ccaaatttga ccgctaccgc ctcaattaca gtctccccac     3480

aggccagtgg gtgggagtgc agcttccaag aaacaccact tcctatgtcc tgagaggcct     3540

ggaaccagga caggagtaca atgtcctcct gacagccgag aaaggcagac acaagagcaa     3600

gcccgcacgt gtgaaggcat ccactgaaca agcccctgag ctggaaaacc tcaccgtgac     3660

tgaggttggc tgggatggcc tcagactcaa ctggaccgca gctgaccagg cctatgagca     3720

ctttatcatt caggtgcagg aggccaacaa ggtggaggca gctcggaacc tcaccgtgcc     3780

tggcagcctt cgggctgtgg acataccggg cctcaaggct gctacgcctt atacagtctc     3840

catctatggg gtgatccagg gctatagaac accagtgctc tctgctgagg cctccacagg     3900

ggaaactccc aatttgggag aggtcgtggt ggccgaggtg ggctgggatg ccctcaaact     3960

caactggact gctccagaag gggcctatga gtactttttc attcaggtgc aggaggctga     4020

cacagtagag gcagcccaga acctcaccgt cccaggagga ctgaggtcca cagacctgcc     4080

tgggctcaaa gcagccactc attataccat caccatccgc ggggtcactc aggacttcag     4140

cacaacccct ctctctgttg aagtcttgac agaggaggtt ccagatatgg gaaacctcac     4200

agtgaccgag gttagctggg atgctctcag actgaactgg accacgccag atggaaccta     4260

tgaccagttt actattcagg tccaggaggc tgaccaggtg gaagaggctc acaatctcac     4320

ggttcctggc agcctgcgtt ccatggaaat cccaggcctc agggctggca ctccttacac     4380

agtcaccctg cacggcgagg tcaggggcca cagcactcga ccccttgctg tagaggtcgt     4440

cacagaggat ctcccacagc tgggagattt agccgtgtct gaggttggct gggatggcct     4500

cagactcaac tggaccgcag ctgacaatgc ctatgagcac tttgtcattc aggtgcagga     4560

ggtcaacaaa gtggaggcag cccagaacct cacgttgcct ggcagcctca gggctgtgga     4620

catcccgggc ctcgaggctg ccacgcctta tagagtctcc atctatgggg tgatccgggg     4680

ctatagaaca ccagtactct ctgctgaggc ctccacagcc aaagaacctg aaattggaaa     4740

cttaaatgtt tctgacataa ctcccgagag cttcaatctc tcctggatgg ctaccgatgg     4800

gatcttcgag acctttacca ttgaaattat tgattccaat aggttgctgg agactgtgga     4860

atataatatc tctggtgctg aacgaactgc ccatatctca gggctacccc ctagtactga     4920

ttttattgtc tacctctctg gacttgctcc cagcatccgg accaaaacca tcagtgccac     4980

agccacgaca gaggccctgc cccttctgga aaacctaacc atttccgaca ttaatcccta     5040

cgggttcaca gtttcctgga tggcatcgga gaatgccttt gacagctttc tagtaacggt     5100

ggtggattct gggaagctgc tggaccccca ggaattcaca ctttcaggaa cccagaggaa     5160

gctggagctt agaggcctca taactggcat tggctatgag gttatggtct ctggcttcac     5220

ccaagggcat caaaccaagc ccttgagggc tgagattgtt acagaagccg aaccggaagt     5280

tgacaacctt ctggtttcag atgccacccc agacggtttc cgtctgtcct ggacagctga     5340

tgaaggggtc ttcgacaatt ttgttctcaa aatcagagat accaaaaagc agtctgagcc     5400

actggaaata accctacttg cccccgaacg taccagggac ataacaggtc tcagagaggc     5460

tactgaatac gaaattgaac tctatggaat aagcaaagga aggcgatccc agacagtcag     5520

tgctatagca acaacagcca tgggctcccc aaaggaagtc attttctcag acatcactga     5580

aaattcggct actgtcagct ggagggcacc cacagcccaa gtggagagct tccggattac     5640

ctatgtgccc attacaggag gtacaccctc catggtaact gtggacggaa ccaagactca     5700

gaccaggctg gtgaaactca tacctggcgt ggagtacctt gtcagcatca tcgccatgaa     5760

gggctttgag gaaagtgaac ctgtctcagg gtcattcacc acagctctgg atggcccatc     5820

tggcctggtg acagccaaca tcactgactc agaagccttg gccaggtggc agccagccat     5880

tgccactgtg gacagttatg tcatctccta cacaggcgag aaagtgccag aaattacacg     5940

cacggtgtcc gggaacacag tggagtatgc tctgaccgac ctcgagcctg ccacggaata     6000

cacactgaga atctttgcag agaaagggcc ccagaagagc tcaaccatca ctgccaagtt     6060

cacaacagac ctcgattctc caagagactt gactgctact gaggttcagt cggaaactgc     6120

cctccttacc tggcgacccc cccgggcatc agtcaccggt tacctgctgg tctatgaatc     6180

agtggatggc acagtcaagg aagtcattgt gggtccagat accacctcct acagcctggc     6240

agacctgagc ccatccaccc actacacagc caagatccag gcactcaatg ggcccctgag     6300

gagcaatatg atccagacca tcttcaccac aattggactc ctgtacccct tccccaagga     6360

ctgctcccaa gcaatgctga atggagacac gacctctggc ctctacacca tttatctgaa     6420

tggtgataag gctgaggcgc tggaagtctt ctgtgacatg acctctgatg ggggtggatg     6480

gattgtgttc ctgagacgca aaaacggacg cgagaacttc taccaaaact ggaaggcata     6540

tgctgctgga tttggggacc gcagagaaga attctggctt gggctggaca acctgaacaa     6600

aatcacagcc caggggcagt acgagctccg ggtggacctg cgggaccatg gggagacagc     6660

ctttgctgtc tatgacaagt tcagcgtggg agatgccaag actcgctaca agctgaaggt     6720

ggaggggtac agtgggacag caggtgactc catggcctac cacaatggca gatccttctc     6780

cacctttgac aaggacacag attcagccat caccaactgt gctctgtcct acaaaggggc     6840

tttctggtac aggaactgtc accgtgtcaa cctgatgggg agatatgggg acaataacca     6900

cagtcagggc gttaactggt tccactggaa gggccacgaa cactcaatcc agtttgctga     6960

gatgaagctg agaccaagca acttcagaaa tcttgaaggc aggcgcaaac gggcataaat     7020

tccagggacc actgggtgag agaggaataa ggcccagagc gaggaaagga ttttaccaaa     7080

gcatcaatac aaccagccca accatcggtc cacacctggg catttggtga gagtcaaagc     7140

tgaccatgga tccctggggc caacggcaac agcatgggcc tcacctcctc tgtgatttct     7200

ttctttgcac caaagacatc agtctccaac atgtttctgt tttgttgttt gattcagcaa     7260

aaatctccca gtgacaacat cgcaatagtt ttttacttct cttaggtggc tctgggaatg     7320

ggagaggggt aggatgtaca ggggtagttt gttttagaac cagccgtatt ttacatgaag     7380

ctgtataatt aattgtcatt atttttgtta gcaaagatta aatgtgtcat tggaagccat     7440

cccttttttt acatttcata caacagaaac cagaaaagca atactgtttc cattttaagg     7500

atatgattaa tattattaat ataataatga tgatgatgat gatgaaaact aaggattttt     7560

caagagatct ttctttccaa aacatttctg gacagtacct gattgtattt tttttttaaa     7620

taaaagcaca agtacttttg agtttgttat tttgctttga attgttgagt ctgaatttca     7680

ccaaagccaa tcatttgaac aaagcgggga atgttgggat aggaaaggta agtagggata     7740

gtggtcaagt gggaggggtg gaaaggagac taaagactgg gagagaggga agcacttttt     7800

ttaaataaag ttgaacacac ttgggaaaag cttacaggcc aggcctgtaa tcccaacact     7860

ttgggaggcc aaggtgggag gatagcttaa ccccaggagt ttgagaccag cctgagcaac     7920

atagtgagaa cttgtctcta cagaaaaaaa aaaaaaaaaa aatttaatta ggcaagcgtg     7980

gtagtgcgca cctgtcgtcc cagctactca ggaggctgag gtaggaaaat cactggagcc     8040

caggagttag aggttacagt gagctatgat cacactactg cactccagcc tgggcaacag     8100

agggagaccc tgtctctaaa taaaaaaaga aaagaaaaaa aaagcttaca acttgagatt     8160

cagcatcttg ctcagtattt ccaagactaa tagattatgg tttaaaagat gcttttatac     8220

tcattttcta atgcaactcc tagaaactct atgatatagt tgaggtaagt attgttacca     8280

cacatgggct aagatcccca gaggcagact gcctgagttc aattcttggc tccaccattc     8340

ccaagttccc taacctctct atgcctcagt ttcctcttct gtaaagtagg gacactcata     8400

cttctcattt cagaacattt ttgtgaagaa taaattatgt tatccatttg aggcccttag     8460

aatggtaccc ggtgtatatt aagtgctagt acatgttagc tatcatcatt atcactttat     8520

atgagatgga ctggggttca tagaaaccca atgacttgat tgtggctact actcaataaa     8580

taatagaatt tggatttaaa aaaaa                                           8605


<210>  1856
<211>  2941
<212>  DNA
<213>  homo sapiens

<400>  1856
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtgcct     1560

ttcattatct caagccagat atcgcttggt ttcaaatcct tttgaacacg ttcgacaaaa     1620

gcagtggaga agaggaagac ctggagcaat aaaagacaaa tgcaacattt taaggcaatg     1680

gtttcacatg gttacatatc aaaacatccc aattctttag tgctgatcat cgaggagcta     1740

gaacattcca tttgcttgtg tgcgtgcgtg cgtgtgtgtg tgtgtgtgtg tattgagatt     1800

tacccagact ggtttgggca agcagactgt tctaaaatat aatagaatac cctaaagtat     1860

aacatgtcga tgttcgatgc tgatacttct acaactttaa aactgctcat ttcatgaagc     1920

aagaatggag gaatccttga ctcttacaca ctggaaattg aaataaagat aaatgcaacc     1980

atttttagga agctagacta gctgtaaagg acctcctaaa taaattattt gttactgtat     2040

cctcatttgt aatctagttg tcaataaatg gcccggacat gtcttgctaa caggatatgg     2100

gctaccagga agaaggactt gtttcccttt cctgtgtggg gagaggtgtg tgacgttttt     2160

ccagttcaca tttatttggt agcccacctg ggttggagga agggcacggt ggagagaaag     2220

tgacatgcat tcacatatct gcttatcagt gtgcaatact gtgtacctca tggatgcttt     2280

ggcaatgccc aaggcgatat aagcaaaatc agaagtatat ttttgcaggt gcttttattt     2340

tcacagccca taattcatag tgatagagtg cagtgatgtt tgccatttgc tggacaacca     2400

acacccgggt tgctcctttg attagagacc agatcagata attatgcttt taaactgatt     2460

acgtttacat tcttctcttt tctatgaaag gcagggcaag aacagaagtg ttcacatggc     2520

tctcatgtac ttttaaatta tacaatgata tccaatatta aaagattata ggaactgagg     2580

tttacatacg tttgtgtggt gacattttag aatgtcaata aatttgcttt ttgagatgtt     2640

gagaggaaca agaaggtgga aggcagtgtt atttatttct ttctattctt ggaaccacga     2700

atgaggtagg cacaaataca ttccttttag agttaagaac tatgacgtag cgagttagtg     2760

agactagaca tagtaccgaa tttagttcat gcattggtct tagagggtga tggaacaaga     2820

gaagtactat ctttgtgttg cagcctcaac caacaacaat gtgttgtaaa aatgtctttc     2880

atgtaaaaag tgcagtaaat atttactatt tataatgaat aaacagttat gaaaacttga     2940

a                                                                     2941


<210>  1857
<211>  12778
<212>  DNA
<213>  homo sapiens

<400>  1857
cgcggcccga gcgcctcttt tcgggattaa aagcgccgcc agctcccgcc gccgccgccg       60

tcgccagcag cgccgctgca gccgccgccg ccggagaagc aaccgctggg cggtgagatc      120

cccctagaca tgcggctcgg gggcgggcag ctggtgtcag aggagctgat gaacctgggc      180

gagagcttca tccagaccaa cgacccgtcg ctgaagctct tccagtgcgc cgtctgcaac      240

aagttcacga cggacaacct ggacatgctg ggcctgcaca tgaacgtgga gcgcagcctg      300

tcggaggacg agtggaaggc ggtgatgggg gactcatacc agtgcaagct ctgccgctac      360

aacacccagc tcaaggccaa cttccagctg cactgcaaga cagacaagca cgtgcagaag      420

taccagctgg tggcccacat caaggagggc ggcaaggcca acgagtggag gctcaagtgt      480

gtggccatcg gcaaccccgt gcacctcaag tgcaacgcct gtgactacta caccaacagc      540

ctggagaagc tgcggctgca cacggtcaac tccaggcacg aggccagcct gaagttgtac      600

aagcacctgc agcagcatga gagtggtgta gaaggtgaga gctgctacta ccactgcgtt      660

ctgtgcaact actccaccaa ggccaagctc aacctcatcc agcatgtgcg ctccatgaag      720

caccagcgaa gcgagagcct gcgaaagctg cagcggctgc agaagggcct tccagaggag      780

gacgaggacc tggggcagat cttcaccatc cgcaggtgcc cctccacgga cccagaagaa      840

gccattgaag atgttgaagg acccagtgaa acagctgctg atccagagga gcttgctaag      900

gaccaagagg gcggagcatc gtccagccaa gcagagaagg agctgacaga ttctcctgca      960

acctccaaac gcatctcctt cccaggtagc tcagagtctc ccctctcttc gaagcgacca     1020

aaaacagctg aggagatcaa accggagcag atgtaccagt gtccctactg caagtacagt     1080

aatgccgatg tcaaccggct ccgggtgcat gccatgacgc agcactcggt gcaacccatg     1140

cttcgctgcc ccctgtgcca ggacatgctc aacaacaaga tccacctcca gctgcacctc     1200

acccacctcc acagcgtggc acctgactgc gtggagaagc tcattatgac ggtgaccacc     1260

cctgagatgg tgatgccaag cagcatgttc ctcccagcag ctgttccaga tcgagatggg     1320

aattccaatt tggaagaggc aggaaagcag cctgaaacct cagaggatct gggaaagaac     1380

atcttgccat ccgcaagcac agagcaaagc ggagatttga aaccatcccc tgctgaccca     1440

ggctctgtga gagaagactc aggcttcatc tgctggaaga aggggtgcaa ccaggttttc     1500

aaaacttctg ctgcccttca gacgcatttt aatgaagtgc atgccaagag gcctcagctg     1560

ccggtgtcag atcgccatgt gtacaagtac cgctgtaatc agtgtagcct ggccttcaag     1620

accattgaaa agttgcagct ccattctcag taccatgtga tcagagctgc caccatgtgc     1680

tgtctttgtc agcgcagttt ccgaactttc caggctctga agaagcacct tgagacaagc     1740

cacctggagc tgagtgaggc tgacatccaa cagctttatg gtggcctgct ggccaatggg     1800

gacctcctgg caatgggaga ccccactctg gcagaggacc ataccataat tgttgaggaa     1860

gacaaggagg aagagagtga cttggaagat aaacagagcc caacgggcag tgactctggg     1920

tcagtacaag aagactcggg ctcagagcca aagagagctc tgcctttcag aaaaggtccc     1980

aattttacta tggaaaagtt cctagaccct tctcgccctt acaagtgtac cgtctgcaag     2040

gaatctttca ctcaaaagaa tatcctgcta gtacactaca attctgtctc ccacctgcat     2100

aagttaaaga gagcccttca agaatcagca accggtcagc cagaacccac cagcagccca     2160

gacaacaaac cttttaagtg taacacttgt aatgtggcct acagccagag ttccactctg     2220

gagatccata tgaggtctgt gttacatcaa accaaggccc gggcagccaa gctggaggct     2280

gcaagtggca gcagcaatgg gactgggaac agcagcagta tttccttgag ctcctccacg     2340

ccaagtcctg tgagcaccag tggcagtaac acctttacca cctccaatcc aagcagtgct     2400

ggcattgctc caagctctaa cttactaagc caagtgccca ctgagagtgt agggatgcca     2460

cccctgggga atcctattgg tgccaacatt gcttcccctt cagagcccaa agaggccaat     2520

cggaagaaac tggcagatat gattgcatcc aggcagcagc aacaacagca gcagcaacag     2580

caacaacaac aacaacaaca acaacaacaa gcacaaacgc tggcccaggc ccaggctcaa     2640

gttcaagctc acctgcagca ggagctgcag caacaggctg ccctgatcca gtctcagctg     2700

tttaacccca ccctccttcc tcacttcccc atgacaactg agaccctgct gcaactacag     2760

cagcagcagc acctcctctt ccctttctac atccccagtg ctgagttcca gcttaacccc     2820

gaggtgagct tgccagtgac cagtggggca ctgacactga ctgggacagg cccaggcctg     2880

ctggaagatc tgaaggctca ggttcaggtc ccacagcaga gccatcagca gatcttgccg     2940

cagcagcagc agaaccaact ctctatagcc cagagtcact ctgccctcct tcagccaagc     3000

cagcaccccg aaaagaagaa caaattggtc atcaaagaaa aggaaaaaga aagccagaga     3060

gagagggaca gcgccgaggg gggagagggc aacaccggtc cgaaggaaac actgccagat     3120

gccttgaagg ccaaagagaa gaaagagttg gcaccagggg gtggttctga gccttccatg     3180

ctccctccac gcattgcttc agatgccaga gggaacgcca ccaaggccct gctggagaac     3240

tttggctttg agttggtcat ccagtataat gagaacaagc agaaggtgca gaaaaagaat     3300

gggaagactg accagggaga gaacctggaa aagctcgagt gtgactcctg cggcaagttg     3360

ttttccaaca tcttgatttt aaagagtcat caagagcacg ttcatcagaa ttactttcct     3420

ttcaaacagc tcgagaggtt tgccaaacag tacagagacc actacgataa actgtaccca     3480

ctgaggcccc agaccccaga gccaccacca cctccccctc caccccctcc acccccactt     3540

ccggcagcgc cgcctcagcc ggcgtccaca ccagccatcc ccgcatcagc cccacccatc     3600

acctcaccta caattgcacc ggcccagcca tcagtgccgc tcacccagct ctccatgccg     3660

atggagctgc ccatcttctc gccgctgatg atgcagacga tgccgctgca gaccttgccg     3720

gctcagctac ccccgcagct gggacctgtg gagcctctgc ctgcggacct ggcccaactc     3780

taccagcatc agctcaatcc aaccctgctc cagcagcaga acaagaggcc tcgcaccagg     3840

atcacagatg atcagctccg agtcttgcgg caatattttg acattaacaa ctcccccagt     3900

gaagagcaaa taaaagagat ggcagacaag tccgggttgc cccagaaagt gatcaagcac     3960

tggttcagga acactctctt caaagagagg cagcgtaaca aggactcccc ttacaacttc     4020

agtaatcctc ctatcaccag cctggaggag ctcaagattg actcccggcc cccttcgccg     4080

gaacctccaa agcaggagta ctggggaagc aagaggtctt caagaacaag gtttacggac     4140

taccagctga gggtcttaca ggacttcttc gatgccaatg cttacccaaa ggatgatgaa     4200

tttgagcaac tctctaattt actgaacctt ccaacccgag tgatagtggt gtggtttcag     4260

aatgcccgac agaaggccag gaagaattat gagaatcagg gagagggcaa agatggagag     4320

cggcgtgagc ttacaaatga tagatacatt cgaacaagca acttgaacta ccagtgcaaa     4380

aaatgtagcc tggtgtttca gcgcatcttt gatctcatca agcaccagaa gaagctgtgt     4440

tacaaggatg aggatgagga ggggcaggac gacagccaaa atgaggattc catggatgcc     4500

atggaaatcc tgacgcctac cagctcatcc tgcagtaccc cgatgccctc acaggcttac     4560

agcgccccag caccatcagc caataataca gcttcctccg ctttcttgca gcttacagcg     4620

gaggctgagg aactggccac cttcaattca aaaacagagg caggcgatga gaaaccaaag     4680

ctggcggaag ctcccagtgc acagccaaac caaacccaag aaaagcaagg acaaccaaag     4740

ccagagctgc agcagcaaga gcagcccgag cagaagacca acactcccca gcagaagctc     4800

ccccagctgg tgtccctgcc ttcgttgcca cagcctcctc cacaagcgcc ccctccacag     4860

tgccccttac cccagtcgag ccccagtcct tcccagctct cccacctgcc cctcaagccc     4920

ctccacacat caactcctca acagctcgca aacctacctc ctcagctaat cccctaccag     4980

tgtgaccagt gtaagttggc atttccgtca tttgagcact ggcaggagca tcagcagctc     5040

cacttcctga gcgcgcagaa ccagttcatc cacccccagt ttttggacag gtccctggat     5100

atgcctttca tgctctttga tcccagtaac ccactcctgg ccagccagct gctctctggg     5160

gccatacctc agattccagc aagctcagcc acttctcctt caactccaac ctccacaatg     5220

aacactctca agaggaagct ggaggaaaag gccagtgcaa gccctggcga aaacgacagt     5280

gggacaggag gagaagagcc tcagagagac aagcgtttga gaacaaccat cacaccggaa     5340

caactagaaa ttctctacca gaagtatcta ctggattcca atccgactcg aaagatgttg     5400

gatcacattg cacacgaggt gggcttgaag aaacgtgtgg tacaagtctg gtttcagaac     5460

acccgagctc gggaaaggaa aggacagttc cgggctgtag gcccagcgca ggcccacagg     5520

agatgccctt tttgcagagc gctcttcaaa gccaagactg ctcttgaggc tcatatccgg     5580

tcccgtcact ggcatgaagc caagagagct ggctacaacc taactctgtc tgcgatgctc     5640

ttagactgtg atgggggact ccagatgaaa ggagatattt ttgacggaac tagcttttcc     5700

cacctacccc caagcagtag tgatggtcag ggtgtccccc tctcacctgt gagtaaaacc     5760

atggaattgt cacccagaac tcttctaagc ccttcctcca ttaaggtgga agggattgaa     5820

gactttgaaa gcccctccat gtcctcagtt aatctaaact ttgaccaaac taagctggac     5880

aacgatgact gttcctctgt caacacagca atcacagata ccacaactgg agacgagggc     5940

aacgcagata acgacagtgc aacgggaata gcaactgaaa ccaaatcctc ttctgcaccc     6000

aacgaagggt tgaccaaagc ggccatgatg gcaatgtctg agtatgaaga tcggttgtca     6060

tctggtctgg tcagcccggc cccgagcttt tatagcaagg aatatgacaa tgaaggtaca     6120

gtggactaca gtgaaacctc aagccttgca gatccctgct ccccgagtcc tggtgcgagt     6180

ggatctgcag gcaaatctgg tgacagcgga gatcggcctg ggcagaaacg ttttcgcact     6240

caaatgacca atctgcagct gaaggtcctc aagtcatgct ttaatgacta caggacaccc     6300

actatgctag aatgtgaggt cctgggcaat gacattggac tgccaaagag agtcgttcag     6360

gtctggttcc agaatgcccg ggcaaaagaa aagaagtcca agttaagcat ggccaagcat     6420

tttggtataa accaaacgag ttatgaggga cccaaaacag agtgcacttt gtgtggcatc     6480

aagtacagcg ctcggctgtc tgtacgtgac catatctttt cccaacagca tatctccaaa     6540

gttaaagaca ccattggaag ccagctggac aaggagaaag aatactttga cccagccacc     6600

gtacgtcagt tgatggctca acaagagttg gaccggatta aaaaggccaa cgaggtcctt     6660

ggactggcag ctcagcagca agggatgttt gacaacaccc ctcttcaggc ccttaacctt     6720

cctacagcat atccagcgct ccagggcatt cctcctgtgt tgctcccggg cctcaacagc     6780

ccctccttgc caggctttac tccatccaac acagctttaa cgtctcctaa gccgaacttg     6840

atgggtctgc ccagcacaac tgttccttcc cctggcctcc ccacttctgg attaccaaat     6900

aaaccgtcct cagcgtcgct gagctcccca accccagcac aagccacgat ggcgatgggc     6960

cctcagcaac ccccccagca gcagcagcag cagcagcaac cacaggtgca gcagcctccc     7020

ccgccgccag cagcccagcc gccacccaca ccacagctcc cactgcaaca gcagcagcaa     7080

cgcaaggaca aagacagtga gaaagtaaag gagaaggaaa aggcacacaa agggaaaggg     7140

gaacccctgc ctgtccccaa gaaggagaaa ggagaggccc ccacggcaac tgcagccacg     7200

atctcagccc cgctgcccac catggagtat gcggtagacc ctgcacagct gcaggccctg     7260

caggccgcgt tgacttcgga ccccacagca ttgctcacaa gccagttcct tccttacttt     7320

gtaccaggct tttctcctta ttatgctccc cagatccctg gcgccctgca gagcgggtac     7380

ctgcagccta tgtatggcat ggaaggcctg ttcccctaca gccctgcact gtcgcaggcc     7440

ctgatggggc tgtccccagg ctccctactg cagcagtacc agcaatacca gcagagtctg     7500

caggaggcaa ttcagcagca gcagcagcgg caactacagc agcagcagca gcaaaaagtg     7560

cagcagcagc agcccaaagc aagccaaacc ccagtccccc ccggggctcc ttccccagac     7620

aaagaccctg ccaaagaatc ccccaaacca gaagaacaga aaaacacccc ccgtgaggtg     7680

tcccccctcc tgccgaaact ccctgaagag ccagaagcag aaagcaaaag tgcggactcc     7740

ctctacgacc ccttcattgt tccaaaggtg cagtacaagt tggtctgccg caagtgccag     7800

gcgggcttca gcgacgagga ggcagcgagg agccacctga agtccctctg cttcttcggc     7860

cagtctgtgg tgaacctgca agagatggtg cttcacgtcc ccaccggcgg cggcggcggt     7920

ggcagtggcg gcggcggcgg cggtggcggc ggcggcggcg gcggcggctc gtaccactgc     7980

ctggcgtgcg agagcgcgct ctgtggggag gaagctctga gtcaacatct cgagtcggcc     8040

ttgcacaaac acagaacaat cacgagagca gcaagaaacg ccaaagagca ccctagttta     8100

ttacctcact ctgcctgctt ccccgatcct agcaccgcat ctacctcgca gtctgccgct     8160

cactcaaacg acagcccccc tcccccgtcg gccgccgccc cctcctccgc ttccccccac     8220

gcctccagga agtcttggcc gcaagtggtc tcccgggctt cggcagcgaa gcccccttct     8280

tttcctcctc tctcctcatc ttcaacggtt acctcaagtt catgcagcac ctcaggggtt     8340

cagccctcga tgccaacaga cgactattcg gaggagtctg acacggatct cagccaaaag     8400

tccgacggac cggcgagccc ggtggagggt cccaaagacc ccagctgccc caaggacagt     8460

ggtctgacca gtgtaggaac ggacaccttc agattgtaag ctttgaagat gaacaataca     8520

aacaaatgaa tttaaataca aaaattaata acaaaccaat ttcaaaaata gactaactgc     8580

aattccaaag cttctaacca aaaaacaaaa aaaaaaaaaa aaagaaaaaa aagaaaaagc     8640

gtgggttgtt ttcccatata cctatctatg ccggtgattt tacattcttg tctttttctt     8700

ttcttttaat attaaaaaaa aaaaaaaagc cctaaccctg ttacattgtg tccttttgaa     8760

ggtactattg gtctgggaaa cagaagtccg cagggcctcc ctaatgtctt tggagcttaa     8820

accccttgta tatttgcccc ttttcaataa acgccccacg ctgatagcac agaggagccc     8880

ggcatgcact gtatgggaaa gcagtccacc ttgttacagt tttaaatttc ttgctatctt     8940

agcattcaga taccaatggc ttgctaaaag aaaaaaagaa atgtaatgtc tttttattct     9000

caggtcaatc gctcacactt tgttttcaga atcattgttt tatatattat tgttttttca     9060

gttttttttt ttttttttgt tccagaaaag attttttgtt ttgttaactt aaaaatgggc     9120

agaaagtatt caagaaaaac aatgtgaact gctttagctt tctggggatt tttaaggata     9180

gcttttctgc tgaagccaat ttcaagggga aaagttaagc actcccactt tcaaaaaaaa     9240

aaaaaaataa taacccacac acacaaagag tgttgaggac ttgtagctta aaaaaaataa     9300

gttttaaaaa ctgactttct gtatttatga tagatatgac catttttggt gttgagtaga     9360

ttgttgcatt ggaaatgaac tgaagcagta tggtagattt aaaaggaaaa aaaaaaaaaa     9420

accttttgtg tacatttagc tttttgtatg gtccagctga cagctcctca tttgatgttg     9480

tcttgttcat tcctagcaga tgatagattg caatccgttg attcgcctaa gcttttctcc     9540

ccttgtccct taattccact ttctctttct tgtcccttaa ttccactttc tctttccttc     9600

tcccacctcc cgtcctataa tctcccactt aaggtagctg ccttcatttc ttagagggag     9660

ctgcagaatt attttataaa actaaagaaa gaatttcaag ggattctagg ggtcattagg     9720

atcctcacag attatttttg gttggggagt tgaaactttt taaaggcata taattctagt     9780

tacctgtgtc tgttagcttt gtgcatttat tttttattta tccttctttt ggcttttttt     9840

tctttgtacc ccttcttttc ctccttgttt ggtaggagct tcaaatattc tttttttttc     9900

tatactaaag gatttgtttc catttgtgta attggctgtg tacttttctt ttctaaaaaa     9960

agtttttggt tagggatttg gtttttggtt ttgtgtttgt tttttctttc ctctctcaga    10020

aaaaaaaatt tcatgcttta aataaaatcc aaagacacac cctttcactg ctgatgcaga    10080

aaaaagggaa agggttcttg ttacttgaga atttgtttct gatttaaaca aacaagactt    10140

agtttaataa aagaaagaga aaaacaaaag attcccaggt tgttatgtgc ttcttctgca    10200

agcagagagg caaatgttaa tgacaattcc atataccaaa agacacattt tttacttcaa    10260

agttttgtcc ttgtgttagg cagtctgagc agcgagtgat ccagagcgca gccaacaaag    10320

cagcagatag cagtgtacag aaagcaaaaa aggaactgta tgtgaggcac ttgtttctgt    10380

taatatccat attcctgtta acacacaccc tttctcatgt aaaaagaaaa ataaataaat    10440

ggtctgaact ttgaaaactt tgtgctgcta aaacatagat tttggagaca aataaataga    10500

tgctttgctg tttcactttc atagctaaac atcaacagaa accatctccc cttgccccca    10560

aagtgtgaaa tccttcttcc cttcgttttc ttccttatgt ttcaaaaggg aactttgaag    10620

actgtgaata caggttccat tggtcacctt tcgggcttct ttccccagtg ctgaagccac    10680

tcatcgactt tgcaaaagac tggagcattc caagatctga aaatggattt tttttctttt    10740

tttctttttt agccgggact attttatttt tatgaatttg tttttagttt aatgaaatag    10800

tagatcctga aatgttgtac atatttctaa ctaggctgat gcacagtgca aattcctttt    10860

ttaattgttt tttttaagta gaaatactaa agaaagaata ccatctaact attcatacca    10920

gtatccagtt gtagcataag gtgtcaaaag caagtacgca aaacatttac tgttttaaca    10980

agctatttcc ttttaacaag aaatcttgta tttcttcctg tgtttgagat gaacattttt    11040

aaattttaaa gttgtacagt tttttgtttt ccattatttt atcttgtttg taactctatg    11100

aaatatatat atatatattt tttgccattt aactgttgta tgttactctg tgtctgtacc    11160

atatagaaaa aaaattgttt ttgtttttgg ttctctatgt gatatcagtt aacaatgtaa    11220

cactagcttt acctgtcaaa ttctgctagg tcttctctga aaacgttgtt tttaaaaatg    11280

atattgcttg gtaatagtgc aatttctatc cttttccctc ccccctcaac ttttaagttc    11340

ttttctttat aattttgctg ccccctccct gatggtttgg gtttttgttt ttgtttttgt    11400

tttttttttt catggagcta ctatgccatc ctccctctgt gaggcagagt gactgtcagt    11460

gttttgttat gccatgcctt gagctgtggg tgtttggcga caataaggtg gttgaataga    11520

ttggctgagc acacttccac ccacctagtg ttctcagagg ggttatgtga ttgtttcaac    11580

ctggagtggg ttgcaccctt aatgctttcc tctgcaacta aaccgcccac atatatgttc    11640

attgaaaaaa gtaagaataa ttctcagcac taacccagaa gtagcaaagc agtcagtgat    11700

ggtgaacatt agaggtcaaa catgagttag atgtttgtgg gctgacagcc atcgtggcta    11760

tgaccagtac tatttacaaa gcatgaattc actacaatgc tcaactgttt gtttagcttt    11820

atctcacttg gggaatttat tcctgtctgc tgcattgtag gtagctgggt aggatatatt    11880

tccacttgct ttttaaatta gttcttcacc tccattgaca ctcgtttttt ggttttctcc    11940

ctatagtgtg ggttggtgct agacaccagt ctgacccaca gaatgggagt tatttcatcc    12000

atctttcctc catccttcca aaaaccacat atctacacaa ggaaaaattt aatacatcta    12060

ggaatttttt ttttaattac aagctattta aagagatgaa tgtggccaaa gttttacaca    12120

attgaaaata aagtaaaaca gacggcatgt gtttaaacct gagtttatca ggcatggcag    12180

gaagttgcag gagagagagg cagtgaccca agccagtgca cttgatgttc atggacatat    12240

atttttttta aataataaat taaaacattt taaatagaag cataaattga gttgtttgtt    12300

ggcgctgaga tactgcccac tgtgaaacaa agctttgact agttttttgt ttgtttactt    12360

tcttcagggg ggaggggggc aagtttgggt aggaaagaaa gcataaatga acgtgaccct    12420

gaggtgaaga ggtatatgaa cagcctttgc aatgtacaaa aagaaaaaaa aacaaaaaac    12480

aacaaaaaaa atagagcaag tgaaaccaaa aatgatgttc ttggtgtttt tctataatgt    12540

agtcttgtta gcttttttgt tactgtaaca atgctgatct cgaactgtac caaaatacat    12600

ggagactaac aaacagaacc acatggaact ttcaaactga aaaaaaaatt tgtcacaaaa    12660

actttgttgt catagttaag ttgattgtag atggtaattg aatatactcc tttgaaaata    12720

tttcatcaag tatgtttcct gctcattgtg atacattaaa aaaaaaatat gagcaaaa      12778


<210>  1858
<211>  5266
<212>  DNA
<213>  homo sapiens

<400>  1858
gtgtgtgcgc gcgcgcgtga gtgagagagg agagagggag aagagagcgc gagagagggg       60

gggctatttc ctaggggcgc cgatcaagaa tacagtgcat ttcgagtagg gatggttcag      120

ttttccactt cggagttcag actgacaccc cacatcgaca atttggaggt ggcaaacagc      180

ttcgcagtca ctaatgcttt ctgctcccag ttttcgagag gagtctatgc tatttttgga      240

ttttatgaca agaagtctgt aaataccatc acatcatttt gcggaacact ccacgtctcc      300

ttcatcactc ccagcttccc aacagatggc acacatccat ttgtcattca gatgagaccc      360

gacctcaaag gagctctcct tagcttgatt gaatactatc aatgggacaa gtttgcatac      420

ctctatgaca gtgacagagg cttatcaaca ctgcaagctg tgctggattc tgctgctgaa      480

aagaaatggc aagtgactgc tatcaatgtg ggaaacatta acaatgacaa gaaagatgag      540

atgtaccgat cactttttca agatctggag ttaaaaaagg aacggcgtgt aattctggac      600

tgtgaaaggg ataaagtaaa cgacattgta gaccaggtta ttaccattgg aaaacatgtt      660

aaagggtacc actacatcat tgcaaatctg ggatttactg atggagacct attaaaaatc      720

cagtttggag gtgcaaatgt ctctggattt cagatagtgg actatgatga ttcgttggta      780

tctaaattta tagaaagatg gtcaacactg gaagaaaaag aataccctgg agctcacaca      840

acaacaatta agtatacttc tgctctgacc tatgatgccg ttcaagtgat gactgaagcc      900

ttccgcaacc taaggaagca aagaattgaa atctcccgaa gggggaatgc aggagactgt      960

ctggcaaacc cagcagtgcc ctggggacaa ggtgtagaaa tagaaagggc cctcaaacag     1020

gttcaggttg aaggtctctc aggaaatata aagtttgacc agaatggaaa aagaataaac     1080

tatacaatta acatcatgga gctcaaaact aatgggcccc ggaagattgg ctactggagt     1140

gaagtggaca aaatggttgt tacccttact gagctccctt ctggaaatga cacctctggg     1200

cttgagaata agactgttgt tgtcaccaca attttggaat ctccgtatgt tatgatgaag     1260

aaaaatcatg aaatgcttga aggcaatgag cgctatgagg gctactgtgt tgacctggct     1320

gcagaaatcg ccaaacattg tgggttcaag tacaagttga caattgttgg tgatggcaag     1380

tatggggcca gggatgcaga cacgaaaatt tggaatggga tggttggaga acttgtatat     1440

gggaaagctg atattgcaat tgctccatta actattaccc ttgtgagaga agaggtgatt     1500

gacttctcaa agcccttcat gagcctcggg atatctatca tgatcaagaa gcctcagaag     1560

tccaaaccag gagtgttttc ctttcttgat cctttagcct atgagatctg gatgtgcatt     1620

gtttttgcct acattggggt cagtgtagtt ttattcctgg tcagcagatt tagcccctac     1680

gagtggcaca ctgaggagtt tgaagatgga agagaaacac aaagtagtga atcaactaat     1740

gaatttggga tttttaatag tctctggttt tccttgggtg cctttatgcg gcaaggatgc     1800

gatatttcgc caagatccct ctctgggcgc attgttggag gtgtgtggtg gttctttacc     1860

ctgatcataa tctcctccta cacggctaac ttagctgcct tcctgactgt agagaggatg     1920

gtgtctccca tcgaaagtgc tgaggatctt tctaagcaaa cagaaattgc ttatggaaca     1980

ttagactctg gctccactaa agagtttttc aggagatcta aaattgcagt gtttgataaa     2040

atgtggacct acatgcggag tgcggagccc tctgtgtttg tgaggactac ggccgaaggg     2100

gtggctagag tgcggaagtc caaagggaaa tatgcctact tgttggagtc cacgatgaac     2160

gagtacattg agcaaaggaa gccttgcgac accatgaaag ttggtggaaa cctggattcc     2220

aaaggctatg gcatcgcaac acctaaagga tcctcattaa gaaccccagt aaatcttgca     2280

gtattgaaac tcagtgagca aggcgtctta gacaagctga aaaacaaatg gtggtacgat     2340

aaaggtgaat gtggagccaa ggactctgga agtaaggaaa agaccagtgc cctcagtctg     2400

agcaacgttg ctggagtatt ctacatcctt gtcgggggcc ttggtttggc aatgctggtg     2460

gctttgattg agttctgtta caagtcaagg gccgaggcga aacgaatgaa ggtggcaaag     2520

aatgcacaga atattaaccc atcttcctcg cagaattcac agaattttgc aacttataag     2580

gaaggttaca acgtatatgg catcgaaagt gttaaaattt aggggatgac cttgaatgat     2640

gccatgagga acaaggcaag gctgtcaatt acaggaagta ctggagaaaa tggacgtgtt     2700

atgactccag aatttcccaa agcagtgcat gctgtccctt acgtgagtcc tggcatggga     2760

atgaatgtca gtgtgactga tctctcgtga ttgataagaa ccttttgagt gccttacaca     2820

atggttttct tgtgtgttta ttgtcaaagt ggtgagaggc atccagtatc ttgaagactt     2880

ttctttcagc caagaattct taaatatgtg gagttcatct tgaattgtaa ggaatgatta     2940

attaaaacac aacatctttt tctactcgag ttacagacaa agcgtggtgg acatgcacag     3000

ctaacatgga agtactataa tttacctgaa gtctttgtac agacaacaaa cctgtttctg     3060

cagccactat tgttagtctc ttgattcata atgacttaag cacacttgac atcaactgca     3120

tcaagatgtg acatgtttta taaaaaaagg aaaaaaaaca tttaaaacta aaaaatattt     3180

ttaggtattt tcacaaacaa actggctttt aaataaattt gcttccatat tggttgaata     3240

agacaaaaac aattaaactg agtgggaagt gaataaaaaa aggctttagg tatcgattcc     3300

atatttttca aagccaaata tgtaaatgct aaggaaagta aacaaagagg agattccaat     3360

cttgtaattt aatattgtta ttaaaacttt aatgtatcct attctttaac atttggtgtt     3420

aatataaaat tacttggcaa tgcttgacat ttgaaataaa catttttcta ttgttttatt     3480

gcaagtggtc caattaattt tgcttagcta cagtttggtc ataaatcaag tgagtttaaa     3540

gacactacca agttgttagg tgcccagaga aaatttctcc cttttaaaaa ggccaggtga     3600

tttttcaaat gtaatcttgc ccccaaagta atatctgaat atctttttga catgtctaaa     3660

tatatatata tataaagaaa tatttgttaa cacaaaagca tttgatctat gtagataaat     3720

gctaatagat ttaaaaagct aatattaaca aataccagaa tacgtgaagt tccattttta     3780

aagtgtttga gcttacagaa gagaaacatt cattttaaat gaagtaaaaa atgccttgaa     3840

agtaattctt tagatagttg cccattgatt aaattccaaa aactaaatat gtttttagct     3900

ttaaaattat aaaagctgtc ataaacttta tatattatga attttaaaat atgtttgagt     3960

ctcctgcaat atagtttcat cccattgaca tcaattaaaa ataaccctaa tatattattt     4020

ttatatttat tcctcaggtg gaatggctat tttaatatgc ccagtgtgga taaaatgtca     4080

catttctgta acttttgact aaagagccta tatttatcta gttaatgaat ttaaaggatc     4140

tatctttccc ttcataaaat acctcttatt tccattaaag ccccccaagt ttaattaatt     4200

taggattttg aatgattatt gacatccaat agttattttt aatatttgta ttcttgttat     4260

ttctggaaga aagcctttgt gtagcacttg gtattttgca aagtgctttt aaaacattct     4320

tacttaccgt atttcataga agggaaggaa aaatgtaagg tttaacagta agcacttgca     4380

ttgaacatgg aggcatgtgg tatcatgata ttcttcacta aatttagctg tccctaatca     4440

cagatcctaa ggtaatataa tataatttta gtgcatttct cctcatcagg aatgctggag     4500

gtgcatttta agttttaata ataagtgcta gaatgaccaa attgcagact aattgtttcc     4560

atattgtact taaaatgagt ttttaaaagt gaaaaagaaa tgactatata caatcaatgc     4620

tatttattgt acctctgggc ctactcttct aaaaattgta gcttatcgat ttttctctgt     4680

caagcttgaa ctaatgtaaa taattgaaat aatgtaaagt tatattttca tgtttttata     4740

gatacaacat gacaagaata cataatgtaa gagtatttca actatggata atgttgattg     4800

gataatgcac atctcagtta caagcagtac tcatagttta atatccatgt aacggtgcat     4860

caatatattg ctatataaat atgtctgtgt gcatataagt gaaaagtggt caaacaagag     4920

tgatgacagc tgtctaaagg tttttttatt cattttatat aaaaactgtt atggaaagac     4980

caaaatgttt atgaactatt cttatgtaaa tttacaattg tcctttactg tacttttttg     5040

tttacagtat agtaccttat tttctgctgt gttaagtggg tgtcaaactc caagaagaca     5100

tacactttct ataacttcta ttgaagatat tggaatttcc aatttttcat gtgtactatg     5160

tcagaaaatg ctttcgattt tatttttaaa tctaacatcg gatggctttt ccggagtgtt     5220

gtaaaaactt caatcataca taaaacatgt tcttacaaaa ggcaaa                    5266


<210>  1859
<211>  5060
<212>  DNA
<213>  homo sapiens

<400>  1859
gtgattgtga agggggagga ggctgtggca ggcaggggtg gtagtagtag tgaatgacac       60

agatttgcca gatgacatgt agcggacctc tgcatcagcc aagaggaatt aagctttgtc      120

actccccact gggactacct ttctcctggt atgtgcgcaa ggaattcata tgctgctgct      180

gctgcagcca ccagagcaga gagccttgag tacactttgc cacagaaagc agtgagcaag      240

aatgatagct gtctctttta aatgccgttg tcaaattctg aggcgactta ctaaagatga      300

gagtccctac actaaatccg ccagccagac aaagccgcct gatggagcgt tggctgtgag      360

gagacagagc atcccagagg aattcaaggg ctccacagtc gtcgagctga tgaagaagga      420

aggcactacc ctgggtctga cggtatcggg aggaattgat aaggatggca agccaagagt      480

atctaatctg cggcaaggag gaattgctgc tagaagtgac cagctggatg tgggtgacta      540

catcaaagca gtgaatggaa tcaacctggc caaattccgc catgacgaga tcatcagctt      600

gctgaagaat gtgggagaaa gagtggttct tgaagtagag tacgagcttc caccggtctc      660

tgtgcaagga tcaagtgtta ttttccgaac agtggaggtc acattacata aagaaggcaa      720

tacctttggt tttgtaattc gagggggagc acatgatgat agaaataaat ctcgtccagt      780

tgtgataaca tgtgttcgtc ctggagggcc tgctgacaga gagggcacga tcaaacccgg      840

tgacaggttg ctcagtgtgg atggaattcg gcttcttgga actacgcatg ctgaagccat      900

gagtattctt aaacaatgtg gacaagaagc agcactgctg atagaatatg atgtctcagt      960

aatggactct gtggcaacag catccgggcc actactagtc gaagttgcca aaactcctgg     1020

tgccagcctt ggggttgccc taactacctc gatgtgctgt aacaaacaag tcattgtcat     1080

agacaaaatc aaatctgcaa gtattgcaga cagatgtggc gcattgcatg tgggagatca     1140

catcctctcc atcgatggaa ccagcatgga gtactgtaca cttgcagaag caacccagtt     1200

cctggccaac accactgacc aggtcaagct tgagatcctt ccccatcatc agacccggct     1260

ggccctaaag gggcccgacc atgcagcttt ggtgtcttca tccttctctc ctacctccat     1320

gagtgcatac agcctgagtt ccctgaacat ggggactcta cctcgaagcc tctactccac     1380

cagcccacgt ggaaccatga tgaggaggag actgaaaaag aaagacttca aaagctcatt     1440

gtccttagcc tccagcacag taggattggc tgggcaggtt gttcacacag aaaccacaga     1500

ggttgtgctg acggcagatc ctgtcacagg atttgggatc caactgcagg gcagtgtgtt     1560

tgccacagaa actctctctt ctccacctct gatttcctat atcgaagctg acagcccagc     1620

agagagatgt ggggtgctac agattggaga cagagtgatg gccatcaatg gaattccaac     1680

agaagacagc accttcgaag aagccagtca gctcctccga gactcttcaa tcacgagcaa     1740

ggtcacactg gaaatcgagt ttgatgttgc agagtctgtc atcccaagta gtggaacatt     1800

tcatgtaaag ctgcctaaga agcacaatgt ggaacttgga ataaccataa gttcaccatc     1860

cagtagaaaa ccaggagacc ccctcgtcat ttcagatatc aagaaaggga gtgtggcaca     1920

cagaactggg accctggaac ttggggataa attgctcgca atagataata tccggctgga     1980

caactgttcc atggaagatg cagttcagat cctccagcaa tgtgaagacc tggtgaagct     2040

caaaatccgc aaagatgaag ataattcaga tgagcaagaa agttccggag caattattta     2100

caccgtggag cttaaacgct acggggggcc ccttggcatc acaatttcag gaactgaaga     2160

gccgtttgat cctataatca tttcaagcct cactaaaggg ggattagctg aaagaactgg     2220

cgcaatccac ataggagacc gaatcctagc catcaatagc agcagcttga aagggaagcc     2280

tctgagtgaa gccatccatt tgttacagat ggcaggagag actgtcacct tgaaaattaa     2340

gaaacagaca gatgcccagt cagcatcgag ccccaagaag ttccctattt ctagccattt     2400

gagtgacctg ggggatgtgg aggaggactc ctcaccagca cagaagccag gcaagctctc     2460

cgacatgtac ccctccacgg tgcccagtgt ggacagtgct gtggattcat gggatgggtc     2520

tgcaatagac accagctatg gaactcaagg cactagtttt caggcctcag gatacaattt     2580

caacacctat gactggagga gtccaaaaca gagaggcagc ttgtccccag tcactaagcc     2640

tcgaagccag acttacccag atgtggggct gagttatgaa gactgggacc ggtccacagc     2700

cagtggtttt gcaggggctg ccgatagtgc agagacagaa caagaggaga acttctggtc     2760

tcaagcgctg gaggatttgg aaacctgcgg acagtcagga attctgagag aactggagga     2820

gaaagctgac aggcgtgtgt ctttgagaaa catgactctc ttggcaacaa tcatgtcggg     2880

gagcacgatg agtttgaatc atgaggctcc aacacctcgc agtcagctgg ggcgacaggc     2940

cagcttccag gagcgcagca gctcgcggcc gcactacagc caaacaactc ggagcaacac     3000

cctgccttca gatgtgggta ggaagtcagt aaccctgaga aaaatgaaac aagaaataaa     3060

ggagatcatg tctccaactc ctgtggagct gcacaaggtg accttgtaca aggactctga     3120

catggaggac tttgggttca gtgtagcaga tggcttactg gagaaaggag tgtatgtcaa     3180

aaatattcgc ccagctgggc caggagatct tggtggctta aagccctatg acaggctctt     3240

acaggtgaat catgtccgaa ccagagactt tgactgctgc cttgttgtgc ccctcatagc     3300

agaatccggg aataagctgg acctggttat tagtagaaac ccactggctt cacagaagtc     3360

tatagaccaa cagagtctac caggagattg gagtgaacag aacagtgctt ttttccagca     3420

gcctagccac ggtggtaatt tggagacacg agaacccact aatacattat agcaacgctt     3480

tttataaagc aggacaaaag acaatatcta catggtgcta aaaatccttt aagatttctg     3540

tgacctttga agcacagata atcaatcaac gtggcattaa ctgcaagcac aggggtcttt     3600

taaatctctc tcatggctca tgttcacttc ccttttcaag ttgaagaggt ttcttttttg     3660

gtgaccacta tggtatatgg tgggcaatgc cctgccagtc ccaacggtag agaaaaatag     3720

gccgtccccc acaactctac aattaacatc agaggaaatt ttttacaagt tcatcttact     3780

atcacttttt aaaaagagaa acatctgttt gaaaatattc tctgtgatga tttccttaat     3840

tcactttgaa atcagtttct tactatgaag tcattaatgt aagaacttgg ccaacaaagc     3900

ttttcttctc ataggctggc tctactaggg gaactagtgt ttggtaaact gctgggacta     3960

ccacaatggg aggggtacag gtataaaatt aagttatctt aaaatgtttc agcaatgatg     4020

cacgtaggag accataatag gtggtggtaa atgttttgcc cacgtatagg aatgatttta     4080

actaagatgt atgctattcc ctatgcaaca aattatcaaa caggatatgt cttgtgacct     4140

gttttttttt taaggacaca tttttaatag ctgaaaatct ctgataatga attagagtgt     4200

gtagtaaaca tgagaattag ttatattatc ttatttttaa aattcaagac taagaacttc     4260

agagaatgaa gagtctatta aaatgaggtt catcttaatg ataggcaaac caaactcata     4320

ctgcttgaca tgttttgaaa actggtaata ttgagggtgt acagcacatg tacttaaaaa     4380

tgacactgga ctatcttttg ctctgagcca tgccacttac cgaaattgta aatacatttt     4440

tcacaaatgc attgccaatt attaccatcc ctcaaagcaa taaattgtga cagttgcttt     4500

aaatgtttgt cagcaactgt tttcatttgt tcagatattt tgaatagcta cactaataac     4560

tgttattatt tggtgaacat aaaaaaataa atagatctgt atattgatgg tagactctcc     4620

atattgaaat gattattttc caaacatttt cattttggtc aataattcaa actaccactt     4680

aggcaaagta ttcgaacact gtgtcctttg tttaaggaaa tataaaaaaa aaatcacctt     4740

tctttttgtg caaaaaaaat attatttcaa tcacatttca gaaccgccag ggcaagaaag     4800

tataaagcag gatcatgtta agaaaaaaga aaaaaagatc atgagtcact taaatatgta     4860

tttttatttg taacaaacaa gtattaaact gtaaagtatt tttgtacaaa tttaatactt     4920

taatagcatg gtatttatcg tctatgtatg gttttgggga attcaaaatt gttcaaatat     4980

ttgtatggaa aaaaataaaa ccctctacca aatggaataa acagtgattt taaaaagcca     5040

aataaagagg atatgcatta                                                 5060


<210>  1860
<211>  5060
<212>  DNA
<213>  homo sapiens

<400>  1860
gtgattgtga agggggagga ggctgtggca ggcaggggtg gtagtagtag tgaatgacac       60

agatttgcca gatgacatgt agcggacctc tgcatcagcc aagaggaatt aagctttgtc      120

actccccact gggactacct ttctcctggt atgtgcgcaa ggaattcata tgctgctgct      180

gctgcagcca ccagagcaga gagccttgag tacactttgc cacagaaagc agtgagcaag      240

aatgatagct gtctctttta aatgccgttg tcaaattctg aggcgactta ctaaagatga      300

gagtccctac actaaatccg ccagccagac aaagccgcct gatggagcgt tggctgtgag      360

gagacagagc atcccagagg aattcaaggg ctccacagtc gtcgagctga tgaagaagga      420

aggcactacc ctgggtctga cggtatcggg aggaattgat aaggatggca agccaagagt      480

atctaatctg cggcaaggag gaattgctgc tagaagtgac cagctggatg tgggtgacta      540

catcaaagca gtgaatggaa tcaacctggc caaattccgc catgacgaga tcatcagctt      600

gctgaagaat gtgggagaaa gagtggttct tgaagtagag tacgagcttc caccggtctc      660

tgtgcaagga tcaagtgtta ttttccgaac agtggaggtc acattacata aagaaggcaa      720

tacctttggt tttgtaattc gagggggagc acatgatgat agaaataaat ctcgtccagt      780

tgtgataaca tgtgttcgtc ctggagggcc tgctgacaga gagggcacga tcaaacccgg      840

tgacaggttg ctcagtgtgg atggaattcg gcttcttgga actacgcatg ctgaagccat      900

gagtattctt aaacaatgtg gacaagaagc agcactgctg atagaatatg atgtctcagt      960

aatggactct gtggcaacag catccgggcc actactagtc gaagttgcca aaactcctgg     1020

tgccagcctt ggggttgccc taactacctc gatgtgctgt aacaaacaag tcattgtcat     1080

agacaaaatc aaatctgcaa gtattgcaga cagatgtggc gcattgcatg tgggagatca     1140

catcctctcc atcgatggaa ccagcatgga gtactgtaca cttgcagaag caacccagtt     1200

cctggccaac accactgacc aggtcaagct tgagatcctt ccccatcatc agacccggct     1260

ggccctaaag gggcccgacc atgcagcttt ggtgtcttca tccttctctc ctacctccat     1320

gagtgcatac agcctgagtt ccctgaacat ggggactcta cctcgaagcc tctactccac     1380

cagcccacgt ggaaccatga tgaggaggag actgaaaaag aaagacttca aaagctcatt     1440

gtccttagcc tccagcacag taggattggc tgggcaggtt gttcacacag aaaccacaga     1500

ggttgtgctg acggcagatc ctgtcacagg atttgggatc caactgcagg gcagtgtgtt     1560

tgccacagaa actctctctt ctccacctct gatttcctat atcgaagctg acagcccagc     1620

agagagatgt ggggtgctac agattggaga cagagtgatg gccatcaatg gaattccaac     1680

agaagacagc accttcgaag aagccagtca gctcctccga gactcttcaa tcacgagcaa     1740

ggtcacactg gaaatcgagt ttgatgttgc agagtctgtc atcccaagta gtggaacatt     1800

tcatgtaaag ctgcctaaga agcacaatgt ggaacttgga ataaccataa gttcaccatc     1860

cagtagaaaa ccaggagacc ccctcgtcat ttcagatatc aagaaaggga gtgtggcaca     1920

cagaactggg accctggaac ttggggataa attgctcgca atagataata tccggctgga     1980

caactgttcc atggaagatg cagttcagat cctccagcaa tgtgaagacc tggtgaagct     2040

caaaatccgc aaagatgaag ataattcaga tgagcaagaa agttccggag caattattta     2100

caccgtggag cttaaacgct acggggggcc ccttggcatc acaatttcag gaactgaaga     2160

gccgtttgat cctataatca tttcaagcct cactaaaggg ggattagctg aaagaactgg     2220

cgcaatccac ataggagacc gaatcctagc catcaatagc agcagcttga aagggaagcc     2280

tctgagtgaa gccatccatt tgttacagat ggcaggagag actgtcacct tgaaaattaa     2340

gaaacagaca gatgcccagt cagcatcgag ccccaagaag ttccctattt ctagccattt     2400

gagtgacctg ggggatgtgg aggaggactc ctcaccagca cagaagccag gcaagctctc     2460

cgacatgtac ccctccacgg tgcccagtgt ggacagtgct gtggattcat gggatgggtc     2520

tgcaatagac accagctatg gaactcaagg cactagtttt caggcctcag gatacaattt     2580

caacacctat gactggagga gtccaaaaca gagaggcagc ttgtccccag tcactaagcc     2640

tcgaagccag acttacccag atgtggggct gagttatgaa gactgggacc ggtccacagc     2700

cagtggtttt gcaggggctg ccgatagtgc agagacagaa caagaggaga acttctggtc     2760

tcaagcgctg gaggatttgg aaacctgcgg acagtcagga attctgagag aactggagga     2820

gaaagctgac aggcgtgtgt ctttgagaaa catgactctc ttggcaacaa tcatgtcggg     2880

gagcacgatg agtttgaatc atgaggctcc aacacctcgc agtcagctgg ggcgacaggc     2940

cagcttccag gagcgcagca gctcgcggcc gcactacagc caaacaactc ggagcaacac     3000

cctgccttca gatgtgggta ggaagtcagt aaccctgaga aaaatgaaac aagaaataaa     3060

ggagatcatg tctccaactc ctgtggagct gcacaaggtg accttgtaca aggactctga     3120

catggaggac tttgggttca gtgtagcaga tggcttactg gagaaaggag tgtatgtcaa     3180

aaatattcgc ccagctgggc caggagatct tggtggctta aagccctatg acaggctctt     3240

acaggtgaat catgtccgaa ccagagactt tgactgctgc cttgttgtgc ccctcatagc     3300

agaatccggg aataagctgg acctggttat tagtagaaac ccactggctt cacagaagtc     3360

tatagaccaa cagagtctac caggagattg gagtgaacag aacagtgctt ttttccagca     3420

gcctagccac ggtggtaatt tggagacacg agaacccact aatacattat agcaacgctt     3480

tttataaagc aggacaaaag acaatatcta catggtgcta aaaatccttt aagatttctg     3540

tgacctttga agcacagata atcaatcaac gtggcattaa ctgcaagcac aggggtcttt     3600

taaatctctc tcatggctca tgttcacttc ccttttcaag ttgaagaggt ttcttttttg     3660

gtgaccacta tggtatatgg tgggcaatgc cctgccagtc ccaacggtag agaaaaatag     3720

gccgtccccc acaactctac aattaacatc agaggaaatt ttttacaagt tcatcttact     3780

atcacttttt aaaaagagaa acatctgttt gaaaatattc tctgtgatga tttccttaat     3840

tcactttgaa atcagtttct tactatgaag tcattaatgt aagaacttgg ccaacaaagc     3900

ttttcttctc ataggctggc tctactaggg gaactagtgt ttggtaaact gctgggacta     3960

ccacaatggg aggggtacag gtataaaatt aagttatctt aaaatgtttc agcaatgatg     4020

cacgtaggag accataatag gtggtggtaa atgttttgcc cacgtatagg aatgatttta     4080

actaagatgt atgctattcc ctatgcaaca aattatcaaa caggatatgt cttgtgacct     4140

gttttttttt taaggacaca tttttaatag ctgaaaatct ctgataatga attagagtgt     4200

gtagtaaaca tgagaattag ttatattatc ttatttttaa aattcaagac taagaacttc     4260

agagaatgaa gagtctatta aaatgaggtt catcttaatg ataggcaaac caaactcata     4320

ctgcttgaca tgttttgaaa actggtaata ttgagggtgt acagcacatg tacttaaaaa     4380

tgacactgga ctatcttttg ctctgagcca tgccacttac cgaaattgta aatacatttt     4440

tcacaaatgc attgccaatt attaccatcc ctcaaagcaa taaattgtga cagttgcttt     4500

aaatgtttgt cagcaactgt tttcatttgt tcagatattt tgaatagcta cactaataac     4560

tgttattatt tggtgaacat aaaaaaataa atagatctgt atattgatgg tagactctcc     4620

atattgaaat gattattttc caaacatttt cattttggtc aataattcaa actaccactt     4680

aggcaaagta ttcgaacact gtgtcctttg tttaaggaaa tataaaaaaa aaatcacctt     4740

tctttttgtg caaaaaaaat attatttcaa tcacatttca gaaccgccag ggcaagaaag     4800

tataaagcag gatcatgtta agaaaaaaga aaaaaagatc atgagtcact taaatatgta     4860

tttttatttg taacaaacaa gtattaaact gtaaagtatt tttgtacaaa tttaatactt     4920

taatagcatg gtatttatcg tctatgtatg gttttgggga attcaaaatt gttcaaatat     4980

ttgtatggaa aaaaataaaa ccctctacca aatggaataa acagtgattt taaaaagcca     5040

aataaagagg atatgcatta                                                 5060


<210>  1861
<211>  5298
<212>  DNA
<213>  homo sapiens

<400>  1861
ctggggcggg ggaatcccgc cccgcccttt ctgtgcggcg cccgggcgca acgcaaacat       60

ggcggcgggt ggcacccgtc ggtgaggcgg tgccgggcgg gggttgtcgg gtgtcatggg      120

cggtggcgac ggcaccgccc ccgcgtctcc ctgagcggga cggcaggggg ggcttctgcg      180

ctgagccggg cgatggacga cagcggcgag ctgggtggtc tggagaccat ggagaccctc      240

acggagctgg gcgacgagct gaccctggga gacatcgacg agatgctgca atttgtcagt      300

aatcaagtgg gagagttccc tgacttgttt tcagaacagc tgtgtagctc ctttcctggc      360

agtggtggta gtggtagcag cagcggcagc agtggcagca gcagcagcag cagcaatggc      420

aggggcagca gcagcggagc tgtggaccct tcagtgcaac ggtcattcac ccaggtcaca      480

ttaccttcct tctctccctc ggcggcctcc ccacaggctc caactctgca agtcaaggtt      540

tctcccacct cagttcccac cacacccagg gcaactccta ttcttcagcc ccgcccccag      600

ccccagcctc aacctcaaac tcagctgcaa caacagacgg taatgatcac gccaacattc      660

agcaccactc cgcagacgag gatcatccag cagcctttga tataccagaa tgcagctact      720

agctttcaag tccttcagcc tcaagtccaa agcctggtga catcctccca ggtacagccg      780

gtcaccattc agcagcaggt gcagacagta caggcccagc gggtgctgac acaaacggcc      840

aatggcacgc tgcagaccct tgccccggct acggtgcaga cagttgctgc gccacaggtg      900

cagcaggtcc cggtcctggt ccagcctcag atcatcaaga cagattccct tgttttgacc      960

acactgaaga cagatggcag ccctgttatg gctgcggtcc agaacccggc cctcaccgcc     1020

ctcaccaccc ctatccagac ggctgccctt caagtaccaa ccctggtggg cagcagtggg     1080

accattctga ccacaatgcc tgtaatgatg gggcaagaga aagtgcccat taagcaggta     1140

cctgggggag tcaagcagct tgagcccccc aaagaaggag aaaggcggac aacccataat     1200

atcattgaga aacgatatcg ctcctccatc aatgacaaaa tcatcgaatt gaaagacctg     1260

gtcatgggga cagacgccaa gatgcacaag tctggcgttc tgaggaaggc cattgattac     1320

atcaaatact tgcagcaggt caatcataaa ctgcgccagg agaacatggt gctgaagctg     1380

gcaaatcaaa agaacaagct tctaaagggc atcgacctag gcagtctggt ggacaatgag     1440

gtggacctga agatcgagga ctttaatcag aatgtccttc tgatgtcccc cccagcctct     1500

gactcagggt cccaggctgg cttctctccc tactccattg actctgagcc aggaagccct     1560

ctattggatg atgcaaaggt caaagatgag ccagactctc ctcctgtggc gctgggcatg     1620

gtagaccgct cacggattct tctgtgtgtc ctcaccttcc tgtgcctctc ctttaacccc     1680

ctgacttccc tgctgcagtg gggaggggcc cacgactctg accagcaccc acactcaggc     1740

tctggccgca gtgtcctgtc attcgagtca ggttctgggg gctggtttga ctggatgatg     1800

cctactcttc tcttatggct ggtaaatggt gtgattgtcc tgagcgtctt tgtgaagctg     1860

ctggttcatg gggagccagt gatccggcca cactcgcgct cctcggtcac cttctggagg     1920

caccggaaac aggcagatct ggatctcgcc agaggagatt ttgcagctgc tgccggcaac     1980

ctacaaacct gcctggcagt tttgggccgg gcactgccca cctcccgcct ggacctggcc     2040

tgcagcctct cctggaacgt gatccgctac agcctgcaga agctacgcct ggtgcgctgg     2100

ctgctcaaga aagtcttcca gtgccggcgg gccacgccag ccactgaggc aggctttgaa     2160

gacgaagcta agaccagcgc ccgggatgcg gctctggcct atcaccggct gcaccagctg     2220

cacatcacag ggaagcttcc tgcaggatcc gcctgttccg atgtacacat ggcgttgtgt     2280

gccgtgaacc tggctgaatg tgcagaggag aagatcccac cgagcacact ggttgagatc     2340

catctgactg ctgccatggg gctcaagacc cggtgtggag gcaagctggg cttcctggcc     2400

agctacttcc tcagccgagc ccagagcctg tgtggccccg agcacagtgc tgttcctgac     2460

tccctgcgct ggctctgcca ccccctgggc cagaagtttt tcatggagcg gagctggtct     2520

gtgaagtcag ctgccaagga gagtctatac tgtgcccaga ggaacccagc tgaccccatt     2580

gcgcaggtcc accaggcctt ctgcaagaac ctgctggagc gagctataga gtccttggtg     2640

aaacctcagg ccaagaagaa ggctggagac caggaagaag agagctgtga attctccagt     2700

gctctggagt acttgaaatt acttcattct tttgtggact ctgtgggggt tatgagcccc     2760

ccactctcca ggagctccgt gctcaagtcc gccctgggtc cagacatcat ctgtcggtgg     2820

tggacgtctg caatcactgt ggccatcagc tggctccagg gagacgatgc agctgtgcgc     2880

tctcatttta ccaaagtgga acgcatcccc aaggccctgg aagtgacaga gagccccctg     2940

gtgaaggcca tcttccatgc ctgcagagcc atgcatgcct cactccctgg gaaagcagat     3000

gggcagcaga gttccttctg ccattgcgag agggccagtg gccacctatg gagcagcctc     3060

aacgtcagtg gggccacctc tgaccctgcc ctcaaccacg tggtccagct gctcacctgt     3120

gacctgctac tgtcgctacg gacagcgctc tggcaaaaac aggccagtgc cagccaggct     3180

gtgggggaga cctaccacgc gtcaggcgct gaactggcgg gcttccaacg ggacctgggc     3240

agcctgcgca ggctggcaca cagcttccgc ccagcatacc gcaaggtgtt cctgcatgaa     3300

gccaccgtgc gcctgatggc aggagccagc cccacccgca cccaccagct gctggaacac     3360

agcctgcggc ggcgcaccac gcagagcacc aagcacggag aggtggatgc ctggcccggc     3420

cagcgagagc gggccaccgc catcctgctg gcctgccgcc acctgcccct ctccttcctc     3480

tcctccccgg gccagcgggc agtgctgctg gccgaagctg cccgcaccct ggagaaggtg     3540

ggcgaccggc gctcctgcaa cgactgccag cagatgattg ttaagctggg tggtggcact     3600

gccattgccg cctcctgacc accaggctca gcccacccct ccacctctct ctcgatttct     3660

ctctctcccc ctcagcatct tcccgctgag agtggtgggg aagagccttg tcttcttagc     3720

tgtcacctgc cgaggcttct gggccactca ggccagtgca cccctgggca gagcccctta     3780

aagctgctgt cactagatgc ccatggtcca gggcctggtg ggcgtgagag gataggtggc     3840

agggcagaaa ctgggcagcc ctgacttgat agcagcaggg ggagctccca agctgccaag     3900

cccctgcctc cagccttcct gagtttctct ctcctgaacc ctactctctc ctttttgctt     3960

cctcagtttt tatcaggctt tctctggggg acagcagtct ctgagcacca gggagcagtt     4020

gccctcaggc ctgtgcccag catgccctcc cctttttata cgaatgtttt ctaccagtgt     4080

gcttgggttt gccatgatgc gaggctgagt tgctgtagcg tcttgattct ctccctgggt     4140

ctgcgttccc tcccctgggc ctgactgagc ctgctcattg tttttccctt tattacacag     4200

gacagccagg ggaggagggg ggcccagccc tgggaggctg gtgggaggca gggggcaggc     4260

ctgcggatgc atgaaataat gttggcatta ttttttaatt ttttaaaaaa taaatggtat     4320

cttatttaat tgtcctgttc cttcccactc cccgcctcct aggatgttag cccaagctca     4380

gggtaggccc agggggctgg gagaaatgaa gccacccatg gggactgggg accaggggcc     4440

ttcagcatgg cttctaggtt ccctcctccc cctaccccat ctcctacctc cacagtacag     4500

actgtcccca acttaacagt ggttcaactt aaaccatgtt tcaactttac aattggtctg     4560

ttggggtatt aaatgaattt gtgacttagg atattttcat ttatgatggg tttatcagga     4620

agtaacccca tggtaagttg aggcatatct gtatatattt aaacctaatt aattcttgag     4680

ctgaaaataa ataaaccagg atggcaggga ccaaccccta atccctcccc agcggcaagc     4740

ccctcttttc agagtgggca gagggttgcc tatggtgggc actaggaatg aggtcccctg     4800

cctcgatgcg ggtcctagga gaaaaagtcc tacttttctg ggtccccagg tgcagcacct     4860

cccggagact gtttctccca tggcctcctg agtgatgggc cctgcctccc tgtgcctcat     4920

cctcaggctg gttggagcag agggtgggca ggagccccag cacagactgg ggggtgctca     4980

cagcagggcc accttgatgc aggctggaat gttatccctg gggtgtgctt ggaccccacc     5040

tgctttcttt ctctcctgcc cctcccctac tctcactgta atttatggac cctgcccgcc     5100

tgcgtgttgt gtgtatgtcc tgtgcctttt ctcactattg tttgggtgtg ggagggggtg     5160

gtttttcact gaaaaggggg gtacacctat agctttcttg atgttcaatc aatcagtcac     5220

tgtgtcccag acatattcaa taaacacaga ttggtaccac ccagcaaaaa aaaaaaaaaa     5280

aaaaaaaaaa aaaaaaaa                                                   5298


<210>  1862
<211>  6824
<212>  DNA
<213>  homo sapiens

<400>  1862
aaggaaacca gcccaatagt ggacctaaca ccccaataat gggaactggc gactcgaaac       60

acacggtttc agtatcccca ggcgccttaa caataagcag cgggttacag aggaaatcga      120

gtctctccgt ggcgcttcca ggctgaggac ccagcgccta ccggccgagc accccctagg      180

gcagaggggc gagggagacc cgcgggaagg ggcagcaagc cgcctgattg acagcccgaa      240

atctgatctt gtgaaagaga cgcggagcca atgggaggca gcgatccatc agtttggatt      300

ggaggcccct ggaggagaag tagaggaaaa accaccgaat tgagctctgt cagaggcgct      360

ttcggcttcc aagggggaag tgctgggcta taattaatgt ttttattaaa tttggaggga      420

agtttttgca gcctttcgcc tagcgtggcc ttcagtcccg ttaggtgcaa agcaagtctc      480

gttgatcgcc attgctagtt ttgcacacgt ttgcgaatca gagctgcccg gggtacaccg      540

accgcgcagg gaaacatcga gagtgtaaat aaatacatcg cctcttgttc ggatttttgc      600

tactaccgaa aatatgtaaa ttgtgaactc tgttggctct ctttggatcc aggttgatag      660

aagtccagat cctgaggaaa tctccagcta aatgctcaaa atataaaata ctgagctgag      720

atttgcgaag agcagcagca tggatggatt ttatgaccag caagtgcctt acatggtcac      780

caatagtcag cgtgggagaa attgtaacga gaaaccaaca aatgtcagga aaagaaaatt      840

cattaacaga gatctggctc atgattcaga agaactcttt caagatctaa gtcaattaca      900

ggaaacatgg cttgcagaag ctcaggtacc tgacaatgat gagcagtttg taccagacta      960

tcaggctgaa agtttggctt ttcatggcct gccactgaaa atcaagaaag aaccccacag     1020

tccatgttca gaaatcagct ctgcctgcag tcaagaacag ccctttaaat tcagctatgg     1080

agaaaagtgc ctgtacaatg tcagtgccta tgatcagaag ccacaagtgg gaatgaggcc     1140

ctccaacccc cccacaccat ccagcacgcc agtgtcccca ctgcatcatg catctccaaa     1200

ctcaactcat acaccgaaac ctgaccgggc cttcccagct cacctccctc catcgcagtc     1260

cataccagat agcagctacc ccatggacca cagatttcgc cgccagcttt ctgaaccctg     1320

taactccttt cctcctttgc cgacgatgcc aagggaagga cgtcctatgt accaacgcca     1380

gatgtctgag ccaaacatcc ccttcccacc acaaggcttt aagcaggagt accacgaccc     1440

agtgtatgaa cacaacacca tggttggcag tgcggccagc caaagctttc cccctcctct     1500

gatgattaaa caggaaccca gagattttgc atatgactca gaagtgccta gctgccactc     1560

catttatatg aggcaagaag gcttcctggc tcatcccagc agaacagaag gctgtatgtt     1620

tgaaaagggc cccaggcagt tttatgatga cacctgtgtt gtcccagaaa aattcgatgg     1680

agacatcaaa caagagccag gaatgtatcg ggaaggaccc acataccaac ggcgaggatc     1740

acttcagctc tggcagtttt tggtagctct tctggatgac ccttcaaatt ctcattttat     1800

tgcctggact ggtcgaggca tggaatttaa actgattgag cctgaagagg tggcccgacg     1860

ttggggcatt cagaaaaaca ggccagctat gaactatgat aaacttagcc gttcactccg     1920

ctattactat gagaaaggaa ttatgcaaaa ggtggctgga gagagatatg tctacaagtt     1980

tgtgtgtgat ccagaagccc ttttctccat ggcctttcca gataatcagc gtccactgct     2040

gaagacagac atggaacgtc acatcaacga ggaggacaca gtgcctcttt ctcactttga     2100

tgagagcatg gcctacatgc cggaaggggg ctgctgcaac ccccacccct acaacgaagg     2160

ctacgtgtat taacacaagt gacagtcaag cagggcgttt ttgcgctttt ccttttttct     2220

gcaagataca gagaattgct gaatctttgt tttatttctg ttgtttgtat tttattttta     2280

aataataata cacaaaaagg ggcttttcct gttgcattat tctatggtct gccatggact     2340

gtgcacttta tttgagggtg ggtgggagta atctaaacat ttattctgtg taacaggaag     2400

ctaatgggtg aatgggcaga gggatttggg gattactttt tacttaggct tgggatgggg     2460

tcctacaagt tttgagtatg atgaaactat atcatgtctg tttgatttca taacaacata     2520

agataatgtt tattttatcg gggtatctat ggtacagtta atttcacgtt gtgtaaatat     2580

ccacttggag actatttgcc ttgggcattt tcccctgtca tttatgagtc tctgcaggtg     2640

tacaaaaaaa ccccaatcta ctgtaaatgg cagtttaatt gttagaaatg actgtttttg     2700

caccacttgt aaaaaggtat ttagcgattg catttgctgt ttgttgtttt attttgcttt     2760

atatatgact tgcagaggat aaccataaaa tgggtaattc tctctgaagt tgaataatca     2820

ccatgactgt aaatgagggg cacaattttg gactctggcg ccaaactgag tcataggcca     2880

gtagcattac gtgtatctgg tgccaccttg ctgtttagat acaaatcata ccgtctttta     2940

aatattttga agcccatttc agttaaataa tgacatgtca tggtcctttg gaatcttcat     3000

ttaaatgtta aatctggaat caaaatgaag caaaaaatat ctgtctcctt ttcactttct     3060

tcagtacata aatacattat ttaatcaata agaattaact gtactaaatc atgtattatg     3120

ctgttctagt tacagcaaac actctttaag aaaaatatcc aatacactaa ataggtacta     3180

tagtaatttt tagacatggt acccattgat atgcatttaa accttttact gctgtgttat     3240

gttgataaca tatataaata ttagataatg ctaatgcttc tgctgctgtc ttttctgtaa     3300

tattctcttt catgctgaat ttactatgac catttataag cagtgcagtt aactacagat     3360

agcatttcag gacaaaatag atgactcaaa ccatttattg cttaaaaaat agcttacgcc     3420

atgctatgct ataagcagct tttatgcaca ttgacaaatg aagagtaagc ttcagcttgc     3480

taaaggaaac tgtggaacct tttgtaactt ttggtgatat ggaaaattat ttacaaaccg     3540

tcaaagaata tgaggaagtt gctgtatgac atagtgctgg cactgatatt atccatcatc     3600

tctttttgga cacttctgta aatgtgattg gattgtttga aagaagattt aaagtttcaa     3660

agttttttgt tctgtttttg ctttgcattt ggagaaaata ttgaaagcag ggtatgttgt     3720

ttcattcacc ttgaaaaaac catgagtaaa tggggatata gaatctctga atagctcgct     3780

aaaagattca agcaagggac atgaattttg ttccatctat caataatatc cagaagaaca     3840

acttttttaa agagtctata gcaaaaagca aaaaaaaaaa aaaattctaa acacaaagtc     3900

aaaataaacc tattgtaaaa gcatttcgtg atgagcatga aaaagattgt ttaaagatga     3960

tccccccagc tacccatttt ccaaaactac acagatcaca gctcatttct ctaagtggag     4020

cagttatcaa gaaacccaaa caccaaaatt gctactcttc acatttaatc ctacaaaaag     4080

tactccaatt tcaaaatatg tatgtaacct gcgatttcaa tgattgttgt tcatatacat     4140

catgtattat tttggcccat tttgggccta aaaaagaaaa ctatgcctta aaaatcagaa     4200

ccttttctcc ccactatgct tatgtggcca tctacagcac ttagaataaa aacagatgtt     4260

aaaatattca gtgaaagttt tattggaaaa aggaattgag atatataatt gagatttggt     4320

gaaattgaag gagaaaattt aagtgagtct ttaaaatata ttctgaatga aaactgtatt     4380

gaggattcat ttttgttcct tttttttctt tttctctttt ctcctttttc ttctttttaa     4440

tagtctagtt ttagtcagtc agtgaggaag aattgggcca tgctaacgtt atcacaagag     4500

aacaatggca gaaatggtat tagttatata atatttaagg acaaactata tgttttgctg     4560

ttttaacgta gtgactcact gaactaaata cataattgac caacattaag tgtatttcca     4620

atacagaagg gttgaaaata ttacattata aactcttttg aaaaatgtat ctaaaatttt     4680

ttaagttctg ttttgattcc actttttggt tgagttttta tgtttttgtt ttcaggtaga     4740

ttaataaatc tggcagctga tttctgcaag attcttgtgt tttgaatttc tcattgaatt     4800

ggctactcaa acatagaaat catttgttaa tgatgtaatg tcttctctca gcttttatct     4860

tcactgctgt ttgctgtctc ttgatgatga catgttaata cccaatagat taattgcaac     4920

aaacacttat actcaaataa ctaagtaaaa ataatttttc ttgttatgtc catgaaaagt     4980

gcttcagaat aaaaatccac aagactgaca gtgcagaaca tttttctcaa atcatgggcg     5040

gatcttggag gtctagtttc ccgtagatgc tgtaaccaat taccacaact tcagtaattt     5100

acacaaattt atcttatagt tctggaggca gaagttcaaa agaagcctta agagactaaa     5160

accaagatgt ccttaggtct ggttccttct ggaggctcca ggggagattc ttccagcttt     5220

cacttctaga gtctgctgac attccttggc tcctggctac atcacttcaa tctctgcttc     5280

catggtcaca tactcttcta ctatagtcaa atttccttcc tgcctcttat aaggatgctt     5340

gtgattacat ttaggggatg ctcagataat ccaggacaat ctctccatct caagatcctt     5400

aacttaatga cgtgtgccaa gtccctttgg ctagataatt attcataggt cccagggatt     5460

aggacatgga tgtaaggggt gagggcaggg ctgttattca gaacaccgca cggaggagga     5520

agactgtgta gcaaagactc taattgattt actcaggaac agtggagttc tgctgaggga     5580

tctaggattt gaaagtacta gagtttgctt ttatttacca ctgagatatt ttccccttat     5640

tctgcataaa taattttgaa aactttctat attaaatttc aactattcca ctaaaatgtc     5700

tggtaatcac atcaagcctt tagattattc aaatccttcc ccagccccca ggaaaacact     5760

aagtcatgaa acagaaaaac agaaggtatg ataataatag taataacagt taaatcagtg     5820

gtctaatcca gattttattt tttaatacat ttcttttggt gttaatatgg gttactatgt     5880

gatcttatca tttgctagtg attattactt attaggtaag aacaatgtgt aaaatatgtc     5940

tattactcaa aagaacaatt gcaaaatgag tcaacttatc tttatataac caggaaagaa     6000

atatattgcc agaagctaca gaattttgcc agatgatagg gatttctaaa atgagccact     6060

ttgtctatca tgcagccttt tcagagcttg taatgagaaa acattacaga ggagaaggtc     6120

atttggatgt ttgttacttg gaatcctaga aaacaaaaac taaaatttaa aaataagaag     6180

tgagtaagct attttccatt tgcgatttgg tatggagaag agaggaaata gaattattaa     6240

aaaaatacaa attgggtaaa agtgatggtg gaaaaaatat aaagaaggca aatgtacata     6300

ttaagcaatt ctactaagaa ttggaaaaat caagtttcaa aaagatggta atagttgggc     6360

atgatactag aaaatttcac ccagtttatt cagagctcaa ctagtacttt taggacttct     6420

ttttttatat acatgagact cactttgaca tacttaaaaa aaaaacagtt tatggaaagt     6480

acagtttaag aggagaattt gattagacta agtggatatc tttatagaaa tattaatgat     6540

ttcagaattt tcagttacaa gtgtatatac cgtggctatt gtttatggat tcatatgtaa     6600

ggtagggtct tttttgcata tagactccag tattagttac tttcattcta aaattatatt     6660

tatgcttcta tggggaagaa aatttttaat tcacttggtt gtattaaaat tatacttacg     6720

gtttgagaaa acatgctatg aaaatcatga ttatagcaaa ttaaatatgc tcaaaattta     6780

aatctaaaat aaaagcccag aaactgaaaa aaaaaaaaaa aaaa                      6824


<210>  1863
<211>  1510
<212>  DNA
<213>  homo sapiens

<400>  1863
ttcctgttgc agataagccc agcttagccc agctgacccc agaccctctc ccctcactcc       60

ccccatgtcg caggatcgag accctgaggc agacagcccg ttcaccaagc cccccgcccc      120

gcccccatca ccccgtaaac ttctcccagc ctccgccctg ccctcaccca gcccgctgtt      180

ccccaagcct cgctccaagc ccacgccacc cctgcagcag ggcagcccca gaggccagca      240

cctatccccg aggctggggt cgaggctcgg ccccgcccct gcctctgcaa cttgagcctg      300

gctgcgaccc ctgctctgac gtctcggaaa attccccctt gcccaggccc ttgggggagg      360

gggtgcatgg tatgaaatgg ggctgagacc cccggctggg ggcagaggaa cccgccagag      420

aacattcaga aggccttcat cgcatccatg gacctgtgga actgggatga ggcatcccca      480

caggaagtgc ctccagggaa caagctggca gggcttgaag gagccaaatt aggcttctgt      540

ttccctgatc tggcactcca aggggacacg ccgacagcga cagcagagac atgctggaaa      600

ggtacaagct catccctggc aagcttccca cagctggact ggggctccgc gttactgcac      660

ccagaagttc catggggggc ggagcccgac tctcaggctc ttccgtggtc cggggactgg      720

acagacatgg cgtgcacagc ctgggactct tggagcggcg cctcgcagac cctgggcccc      780

gcccctctcg gcccgggccc catccccgcc gccggctccg aaggcgccgc gggccagaac      840

tgcgtccccg tggcgggaga ggccacctcg tggtcgcgcg cccaggccgc cgggagcaac      900

accagctggg actgttctgt ggggcccgac ggcgatacct actggggcag tggcctgggc      960

ggggagccgc gcacggactg taccatttcg tggggcgggc ccgcgggccc ggactgtacc     1020

acctcctgga acccggggct gcatgcgggt ggcaccacct ctttgaagcg gtaccagagc     1080

tcagctctca ccgtttgctc cgaaccgagc ccgcagtcgg accgtgccag tttggctcga     1140

tgccccaaaa ctaaccaccg aggtcccatt cagctgtggc agttcctcct ggagctgctc     1200

cacgacgggg cgcgtagcag ctgcatccgt tggactggca acagccgcga gttccagctg     1260

tgcgacccca aagaggtggc tcggctgtgg ggcgagcgca agagaaagcc gggcatgaat     1320

tacgagaagc tgagccgggg ccttcgctac tactatcgcc gcgacatcgt gcgcaagagc     1380

ggggggcgaa agtacacgta ccgcttcggg ggccgcgtgc ccagcctagc ctatccggac     1440

tgtgcgggag gcggacgggg agcagagaca caataaaaat tcccggtcaa acctcaaaaa     1500

aaaaaaaaaa                                                            1510


<210>  1864
<211>  1510
<212>  DNA
<213>  homo sapiens

<400>  1864
ttcctgttgc agataagccc agcttagccc agctgacccc agaccctctc ccctcactcc       60

ccccatgtcg caggatcgag accctgaggc agacagcccg ttcaccaagc cccccgcccc      120

gcccccatca ccccgtaaac ttctcccagc ctccgccctg ccctcaccca gcccgctgtt      180

ccccaagcct cgctccaagc ccacgccacc cctgcagcag ggcagcccca gaggccagca      240

cctatccccg aggctggggt cgaggctcgg ccccgcccct gcctctgcaa cttgagcctg      300

gctgcgaccc ctgctctgac gtctcggaaa attccccctt gcccaggccc ttgggggagg      360

gggtgcatgg tatgaaatgg ggctgagacc cccggctggg ggcagaggaa cccgccagag      420

aacattcaga aggccttcat cgcatccatg gacctgtgga actgggatga ggcatcccca      480

caggaagtgc ctccagggaa caagctggca gggcttgaag gagccaaatt aggcttctgt      540

ttccctgatc tggcactcca aggggacacg ccgacagcga cagcagagac atgctggaaa      600

ggtacaagct catccctggc aagcttccca cagctggact ggggctccgc gttactgcac      660

ccagaagttc catggggggc ggagcccgac tctcaggctc ttccgtggtc cggggactgg      720

acagacatgg cgtgcacagc ctgggactct tggagcggcg cctcgcagac cctgggcccc      780

gcccctctcg gcccgggccc catccccgcc gccggctccg aaggcgccgc gggccagaac      840

tgcgtccccg tggcgggaga ggccacctcg tggtcgcgcg cccaggccgc cgggagcaac      900

accagctggg actgttctgt ggggcccgac ggcgatacct actggggcag tggcctgggc      960

ggggagccgc gcacggactg taccatttcg tggggcgggc ccgcgggccc ggactgtacc     1020

acctcctgga acccggggct gcatgcgggt ggcaccacct ctttgaagcg gtaccagagc     1080

tcagctctca ccgtttgctc cgaaccgagc ccgcagtcgg accgtgccag tttggctcga     1140

tgccccaaaa ctaaccaccg aggtcccatt cagctgtggc agttcctcct ggagctgctc     1200

cacgacgggg cgcgtagcag ctgcatccgt tggactggca acagccgcga gttccagctg     1260

tgcgacccca aagaggtggc tcggctgtgg ggcgagcgca agagaaagcc gggcatgaat     1320

tacgagaagc tgagccgggg ccttcgctac tactatcgcc gcgacatcgt gcgcaagagc     1380

ggggggcgaa agtacacgta ccgcttcggg ggccgcgtgc ccagcctagc ctatccggac     1440

tgtgcgggag gcggacgggg agcagagaca caataaaaat tcccggtcaa acctcaaaaa     1500

aaaaaaaaaa                                                            1510


<210>  1865
<211>  2298
<212>  DNA
<213>  homo sapiens

<400>  1865
cacgttctta tgtaaccgag cccgggtaaa gcagggctgc agaaagcaga aacggcgagc       60

ccggctcctg ggagcaggtc tcggcccccg cttggggccc cggccgtgcg gccggaggga      120

gcggccggat ggagcggagg atgaaagccg gatacttgga ccagcaagtg ccctacacct      180

tcagcagcaa atcgcccgga aatgggagct tgcgcgaagc gctgatcggc ccgctgggga      240

agctcatgga cccgggctcc ctgccgcccc tcgactctga agatctcttc caggatctaa      300

gtcacttcca ggagacgtgg ctcgctgaag ctcaggtacc agacagtgat gagcagtttg      360

ttcctgattt ccattcagaa aacctagctt tccacagccc caccaccagg atcaagaagg      420

agccccagag tccccgcaca gacccggccc tgtcctgcag caggaagccg ccactcccct      480

accaccatgg cgagcagtgc ctttactcca gtgcctatga cccccccaga caaatcgcca      540

tcaagtcccc tgcccctggt gcccttggac agtcgcccct acagcccttt ccccgggcag      600

agcaacggaa tttcctgaga tcctctggca cctcccagcc ccaccctggc catgggtacc      660

tcggggaaca tagctccgtc ttccagcagc ccctggacat ttgccactcc ttcacatctc      720

agggaggggg ccgggaaccc ctcccagccc cctaccaaca ccagctgtcg gagccctgcc      780

caccctatcc ccagcagagc tttaagcaag aataccatga tcccctgtat gaacaggcgg      840

gccagccagc cgtggaccag ggtggggtca atgggcacag gtacccaggg gcgggggtgg      900

tgatcaaaca ggaacagacg gacttcgcct acgactcaga tgtcaccggg tgcgcatcaa      960

tgtacctcca cacagagggc ttctctgggc cctctccagg tgacggggcc atgggctatg     1020

gctatgagaa acctctgcga ccattcccag atgatgtctg cgttgtccct gagaaatttg     1080

aaggagacat caagcaggaa ggggtcggtg catttcgaga ggggccgccc taccagcgcc     1140

ggggtgccct gcagctgtgg caatttctgg tggccttgct ggatgaccca acaaatgccc     1200

atttcattgc ctggacgggc cggggaatgg agttcaagct cattgagcct gaggaggtcg     1260

ccaggctctg gggcatccag aagaaccggc cagccatgaa ttacgacaag ctgagccgct     1320

cgctccgata ctattatgag aaaggcatca tgcagaaggt ggctggtgag cgttacgtgt     1380

acaagtttgt gtgtgagccc gaggccctct tctctttggc cttcccggac aatcagcgtc     1440

cagctctcaa ggctgagttt gaccggcctg tcagtgagga ggacacagtc cctttgtccc     1500

acttggatga gagccccgcc tacctcccag agctggctgg ccccgcccag ccatttggcc     1560

ccaagggtgg ctactcttac tagcccccag cggctgttcc ccctgccgca ggtgggtgct     1620

gccctgtgta catataaatg aatctggtgt tggggaaacc ttcatctgaa acccacagat     1680

gtctctgggg cagatcccca ctgtcctacc agttgcccta gcccagactc tgagctgctc     1740

accggagtca ttgggaagga aaagtggaga aatggcaagt ctagagtctc agaaactccc     1800

ctgggggttt cacctgggcc ctggaggaat tcagctcagc ttcttcctag gtccaagccc     1860

cccacacctt ttccccaacc acagagaaca agagtttgtt ctgttctggg ggacagagaa     1920

ggcgcttccc aacttcatac tggcaggagg gtgaggaggt tcactgagct ccccagatct     1980

cccactgcgg ggagacagaa gcctggactc tgccccacgc tgtggccctg gagggtcccg     2040

gtttgtcagt tcttggtgct ctgtgttccc agaggcaggc ggaggttgaa gaaaggaacc     2100

tgggatgagg ggtgctgggt ataagcagag agggatgggt tcctgctcca agggaccctt     2160

tgcctttctt ctgccctttc ctaggcccag gcctgggttt gtacttccac ctccaccaca     2220

tctgccagac cttaataaag gcccccactt ctcccattaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaa                                                   2298


<210>  1866
<211>  3580
<212>  DNA
<213>  homo sapiens

<400>  1866
gccgggcccc gccgccgccc gcgcgccccc gggcccccga cacacatgag attcttcagg       60

ctcactttca agtgcttcgt ggactgcttc tgactgcgcc gcccgcgccc cgcaccccgc      120

cgcccgcccg ccgccccgtc ccccggcccg gccgcccccc ggcccccggc cggcccgcgc      180

cctcggggcc ctccccggtg ccgccggtgc cccccgcctg accgccgccc cccgtgaggc      240

gccgcgaccc cggcccggcc gtgcggcccg ccgaggccat ggcgaagaag agcgccgaga      300

acggcatcta tagcgtgtcc ggcgacgaga agaagggccc cctcatcgcg cccgggcccg      360

acggggcccc ggccaagggc gacggccccg tgggcctggg gacacccggc ggccgcctgg      420

ccgtgccgcc gcgcgagacc tggacgcgcc agatggactt catcatgtcg tgcgtgggct      480

tcgccgtggg cttgggcaac gtgtggcgct tcccctacct gtgctacaag aacggcggag      540

gtgtgttcct tattccctac gtcctgatcg ccctggttgg aggaatcccc attttcttct      600

tagagatctc gctgggccag ttcatgaagg ccggcagcat caatgtctgg aacatctgtc      660

ccctgttcaa aggcctgggc tacgcctcca tggtgatcgt cttctactgc aacacctact      720

acatcatggt gctggcctgg ggcttctatt acctggtcaa gtcctttacc accacgctgc      780

cctgggccac atgtggccac acctggaaca ctcccgactg cgtggagatc ttccgccatg      840

aagactgtgc caatgccagc ctggccaacc tcacctgtga ccagcttgct gaccgccggt      900

cccctgtcat cgagttctgg gagaacaaag tcttgaggct gtctggggga ctggaggtgc      960

caggggccct caactgggag gtgacccttt gtctgctggc ctgctgggtg ctggtctact     1020

tctgtgtctg gaagggggtc aaatccacgg gaaagatcgt gtacttcact gctacattcc     1080

cctacgtggt cctggtcgtg ctgctggtgc gtggagtgct gctgcctggc gccctggatg     1140

gcatcattta ctatctcaag cctgactggt caaagctggg gtcccctcag gtgtggatag     1200

atgcggggac ccagattttc ttttcttacg ccattggcct gggggccctc acagccctgg     1260

gcagctacaa ccgcttcaac aacaactgct acaaggacgc catcatcctg gctctcatca     1320

acagtgggac cagcttcttt gctggcttcg tggtcttctc catcctgggc ttcatggctg     1380

cagagcaggg cgtgcacatc tccaaggtgg cagagtcagg gccgggcctg gccttcatcg     1440

cctacccgcg ggctgtcacg ctgatgccag tggccccact ctgggctgcc ctgttcttct     1500

tcatgctgtt gctgcttggt ctcgacagcc agtttgtagg tgtggagggc ttcatcaccg     1560

gcctcctcga cctcctcccg gcctcctact acttccgttt ccaaagggag atctctgtgg     1620

ccctctgttg tgccctctgc tttgtcatcg atctctccat ggtgactgat ggcgggatgt     1680

acgtcttcca gctgtttgac tactactcgg ccagcggcac caccctgctc tggcaggcct     1740

tttgggagtg cgtggtggtg gcctgggtgt acggagctga ccgcttcatg gacgacattg     1800

cctgtatgat cgggtaccga ccttgcccct ggatgaaatg gtgctggtcc ttcttcaccc     1860

cgctggtctg catgggcatc ttcatcttca acgttgtgta ctacgagccg ctggtctaca     1920

acaacaccta cgtgtacccg tggtggggtg aggccatggg ctgggccttc gccctgtcct     1980

ccatgctgtg cgtgccgctg cacctcctgg gctgcctcct cagggccaag ggcaccatgg     2040

ctgagcgctg gcagcacctg acccagccca tctggggcct ccaccacttg gagtaccgag     2100

ctcaggacgc agatgtcagg ggcctgacca ccctgacccc agtgtccgag agcagcaagg     2160

tcgtcgtggt ggagagtgtc atgtgacaac tcagctcaca tcaccagctc acctctggta     2220

gccatagcag cccctgcttc agccccaccg cacccctcca gggggcctgc ctttccctga     2280

cacttttggg gtctgcctgg gggaggaggg gagaaagcac catgagtgct cactaaaaca     2340

actttttcca tttttaataa aacgccaaaa atatcacaac ccaccaaaaa tagatgcctc     2400

tccccctcca gccctagccg agctggtcct aggccccgcc tagtgcccca cccccaccca     2460

cagtgctgca ctcctcctgc ccctgccacg cccaccccct gcccacctct ccaggctctg     2520

ctctgcagca cacccgtggg tgacccctca ccccagaagc agcagtggca gcttgggaaa     2580

tgtgaggaag ggaaggaggg agagacggga gggaggagag agaggagaag ggaggcaggg     2640

gaggggcagc agaaccaagg caaatatttc agctgggcta tacccctctc cccatccctg     2700

ttatagaagc ttagagagcc agccagcaat ggaaccttct ggttcctgcg ccaatcgcca     2760

ccagtatcaa ttgtgtgagc ttgggtgcga gtgcacgcgt gcgtgagtac ggagagtata     2820

tatagatctc tatctcttag caaaggtgaa tgccagatgt aaatggcgcc tctgggcaaa     2880

ggaggcttgt attttgcaca ttttataaaa acttgagaga atgagatttc tgcttgtata     2940

tttctaaaaa gaggaaggag cccaaaccat cctctcctta ccactcccat ccctgtgagc     3000

cctaccttac ccctctgccc ctagccaagg agtgtgaatt tatagatcta actttcatag     3060

gcaaaacaaa agcttcgagc tgttgcgtgt gtgagtctgt tgtgtggatg tgcgtgtgtg     3120

gtccccagcc ccagactgga ttggaaaagt gcatggtggg ggcctcgggg ctgtccccac     3180

gctgtccctt tgccacaagt ctgtggggca agaggctgca atattccgtc ctgggtgtct     3240

gggctgctaa cctggcctgc tcaggcttcc caccctgtgc ggggcacacc cccaggaagg     3300

gaccctggac acggctccca cgtccaggct taaggtggat gcacttcccg cacctccagt     3360

cttctgtgta gcagctttaa cccacgtttg tctgtcacgt ccagtcccga gacggctgag     3420

tgaccccaag aaaggcttcc ccgacaccca gacagaggct gcagggctgg ggctgggtga     3480

gggtggcggg cctgcgggga cattctactg tgctaaaaag ccactgcaga catagcaata     3540

aaaacatgtc attttccaaa gcaggaaaaa aaaaaaaaaa                           3580


<210>  1867
<211>  3580
<212>  DNA
<213>  homo sapiens

<400>  1867
gccgggcccc gccgccgccc gcgcgccccc gggcccccga cacacatgag attcttcagg       60

ctcactttca agtgcttcgt ggactgcttc tgactgcgcc gcccgcgccc cgcaccccgc      120

cgcccgcccg ccgccccgtc ccccggcccg gccgcccccc ggcccccggc cggcccgcgc      180

cctcggggcc ctccccggtg ccgccggtgc cccccgcctg accgccgccc cccgtgaggc      240

gccgcgaccc cggcccggcc gtgcggcccg ccgaggccat ggcgaagaag agcgccgaga      300

acggcatcta tagcgtgtcc ggcgacgaga agaagggccc cctcatcgcg cccgggcccg      360

acggggcccc ggccaagggc gacggccccg tgggcctggg gacacccggc ggccgcctgg      420

ccgtgccgcc gcgcgagacc tggacgcgcc agatggactt catcatgtcg tgcgtgggct      480

tcgccgtggg cttgggcaac gtgtggcgct tcccctacct gtgctacaag aacggcggag      540

gtgtgttcct tattccctac gtcctgatcg ccctggttgg aggaatcccc attttcttct      600

tagagatctc gctgggccag ttcatgaagg ccggcagcat caatgtctgg aacatctgtc      660

ccctgttcaa aggcctgggc tacgcctcca tggtgatcgt cttctactgc aacacctact      720

acatcatggt gctggcctgg ggcttctatt acctggtcaa gtcctttacc accacgctgc      780

cctgggccac atgtggccac acctggaaca ctcccgactg cgtggagatc ttccgccatg      840

aagactgtgc caatgccagc ctggccaacc tcacctgtga ccagcttgct gaccgccggt      900

cccctgtcat cgagttctgg gagaacaaag tcttgaggct gtctggggga ctggaggtgc      960

caggggccct caactgggag gtgacccttt gtctgctggc ctgctgggtg ctggtctact     1020

tctgtgtctg gaagggggtc aaatccacgg gaaagatcgt gtacttcact gctacattcc     1080

cctacgtggt cctggtcgtg ctgctggtgc gtggagtgct gctgcctggc gccctggatg     1140

gcatcattta ctatctcaag cctgactggt caaagctggg gtcccctcag gtgtggatag     1200

atgcggggac ccagattttc ttttcttacg ccattggcct gggggccctc acagccctgg     1260

gcagctacaa ccgcttcaac aacaactgct acaaggacgc catcatcctg gctctcatca     1320

acagtgggac cagcttcttt gctggcttcg tggtcttctc catcctgggc ttcatggctg     1380

cagagcaggg cgtgcacatc tccaaggtgg cagagtcagg gccgggcctg gccttcatcg     1440

cctacccgcg ggctgtcacg ctgatgccag tggccccact ctgggctgcc ctgttcttct     1500

tcatgctgtt gctgcttggt ctcgacagcc agtttgtagg tgtggagggc ttcatcaccg     1560

gcctcctcga cctcctcccg gcctcctact acttccgttt ccaaagggag atctctgtgg     1620

ccctctgttg tgccctctgc tttgtcatcg atctctccat ggtgactgat ggcgggatgt     1680

acgtcttcca gctgtttgac tactactcgg ccagcggcac caccctgctc tggcaggcct     1740

tttgggagtg cgtggtggtg gcctgggtgt acggagctga ccgcttcatg gacgacattg     1800

cctgtatgat cgggtaccga ccttgcccct ggatgaaatg gtgctggtcc ttcttcaccc     1860

cgctggtctg catgggcatc ttcatcttca acgttgtgta ctacgagccg ctggtctaca     1920

acaacaccta cgtgtacccg tggtggggtg aggccatggg ctgggccttc gccctgtcct     1980

ccatgctgtg cgtgccgctg cacctcctgg gctgcctcct cagggccaag ggcaccatgg     2040

ctgagcgctg gcagcacctg acccagccca tctggggcct ccaccacttg gagtaccgag     2100

ctcaggacgc agatgtcagg ggcctgacca ccctgacccc agtgtccgag agcagcaagg     2160

tcgtcgtggt ggagagtgtc atgtgacaac tcagctcaca tcaccagctc acctctggta     2220

gccatagcag cccctgcttc agccccaccg cacccctcca gggggcctgc ctttccctga     2280

cacttttggg gtctgcctgg gggaggaggg gagaaagcac catgagtgct cactaaaaca     2340

actttttcca tttttaataa aacgccaaaa atatcacaac ccaccaaaaa tagatgcctc     2400

tccccctcca gccctagccg agctggtcct aggccccgcc tagtgcccca cccccaccca     2460

cagtgctgca ctcctcctgc ccctgccacg cccaccccct gcccacctct ccaggctctg     2520

ctctgcagca cacccgtggg tgacccctca ccccagaagc agcagtggca gcttgggaaa     2580

tgtgaggaag ggaaggaggg agagacggga gggaggagag agaggagaag ggaggcaggg     2640

gaggggcagc agaaccaagg caaatatttc agctgggcta tacccctctc cccatccctg     2700

ttatagaagc ttagagagcc agccagcaat ggaaccttct ggttcctgcg ccaatcgcca     2760

ccagtatcaa ttgtgtgagc ttgggtgcga gtgcacgcgt gcgtgagtac ggagagtata     2820

tatagatctc tatctcttag caaaggtgaa tgccagatgt aaatggcgcc tctgggcaaa     2880

ggaggcttgt attttgcaca ttttataaaa acttgagaga atgagatttc tgcttgtata     2940

tttctaaaaa gaggaaggag cccaaaccat cctctcctta ccactcccat ccctgtgagc     3000

cctaccttac ccctctgccc ctagccaagg agtgtgaatt tatagatcta actttcatag     3060

gcaaaacaaa agcttcgagc tgttgcgtgt gtgagtctgt tgtgtggatg tgcgtgtgtg     3120

gtccccagcc ccagactgga ttggaaaagt gcatggtggg ggcctcgggg ctgtccccac     3180

gctgtccctt tgccacaagt ctgtggggca agaggctgca atattccgtc ctgggtgtct     3240

gggctgctaa cctggcctgc tcaggcttcc caccctgtgc ggggcacacc cccaggaagg     3300

gaccctggac acggctccca cgtccaggct taaggtggat gcacttcccg cacctccagt     3360

cttctgtgta gcagctttaa cccacgtttg tctgtcacgt ccagtcccga gacggctgag     3420

tgaccccaag aaaggcttcc ccgacaccca gacagaggct gcagggctgg ggctgggtga     3480

gggtggcggg cctgcgggga cattctactg tgctaaaaag ccactgcaga catagcaata     3540

aaaacatgtc attttccaaa gcaggaaaaa aaaaaaaaaa                           3580


<210>  1868
<211>  4257
<212>  DNA
<213>  homo sapiens

<400>  1868
agtgtgtgga gaagccactc tcccgaaacc agagggatgg ggccggctgt gcagtagaac       60

ggggatcgaa aagaggaaaa caagggcacg aagaccagcg agaaagaaga ggacacctgg      120

gaaaggcgga agcagaagac ggggaaggga aaagaaaccc aaagcaggtg gaaaccagat      180

ctagagcaac accgtcaggt tcacagtttg tttttctaga agagaagaaa gtacctgagg      240

attgctcttt tttcctaccg ttaatgaaaa ctacttttgt cttcatcata aaagaaaaaa      300

ctaaggggag gtaaaggcag tctcctgttt tattaggggg agaggtgaag ggaaatccag      360

gctcactttc tgaataagcc actgcctggt gcacagagca gaaccatcct ggtttctgaa      420

gacacatccc tttcagcaga attccagccg gagtcgctgg cacagttcta tttttatatt      480

taaatgtatg tctcccctgg cctttttttt tttttttttt tttagcaaca cttttcttgt      540

ttgtaaacgc gagtgaccag aaagtgtgaa tgcggagtag gaatattttt cgtgttctct      600

tttatctgct tgcctttttt agagagtagc agtggttcct atttcggaaa aggacgttct      660

aattcaaagc tctctcccaa tatatttaca cgaatacgca tttagaaagg gaggcagctt      720

ttgaggttgc aatcctactg agaaggatgg aagaaggagc caggcaccga aacaacaccg      780

aaaagaaaca cccaggtggg ggcgagtcgg acgccagccc cgaggctggt tccggagggg      840

gcggagtagc cctgaagaaa gagatcggat tggtcagtgc ctgtggtatc atcgtaggga      900

acatcatcgg ctctggaatc tttgtctcgc caaagggagt gctggagaat gctggttctg      960

tgggccttgc tctcatcgtc tggattgtga cgggcttcat cacagttgtg ggagccctct     1020

gctatgctga actcggggtc accatcccca aatctggagg tgactactcc tatgtcaagg     1080

acatcttcgg aggactggct gggttcctga ggctgtggat tgctgtgctg gtgatctacc     1140

ccaccaacca ggctgtcatc gccctcacct tctccaacta cgtgctgcag ccgctcttcc     1200

ccacctgctt ccccccagag tctggccttc ggctcctggc tgccatctgc ttattgctcc     1260

tcacatgggt caactgttcc agtgtgcggt gggccacccg ggttcaagac atcttcacag     1320

ctgggaagct cctggccttg gccctgatta tcatcatggg gattgtacag atatgcaaag     1380

gagagtactt ctggctggag ccaaagaatg catttgagaa tttccaggaa cctgacatcg     1440

gcctcgtcgc actggctttc cttcagggct cctttgccta tggaggctgg aactttctga     1500

attacgtgac tgaggagctt gttgatccct acaagaacct tcccagagcc atcttcatct     1560

ccatcccact ggtcacattt gtgtatgtct ttgccaatgt cgcttatgtc actgcaatgt     1620

ccccccagga gctgctggca tccaacgccg tcgctgtgac ttttggagag aagctcctag     1680

gagtcatggc ctggatcatg cccatttctg ttgccctgtc cacatttgga ggagttaatg     1740

ggtctctctt cacctcctct cggctgttct tcgctggagc ccgagagggc caccttccca     1800

gtgtgttggc catgatccac gtgaagcgct gcaccccaat cccagccctg ctcttcacat     1860

gcatctccac cctgctgatg ctggtcacca gcgacatgta cacactcatc aactatgtgg     1920

gcttcatcaa ctacctcttc tatggggtca cggttgctgg acagatagtc cttcgctgga     1980

agaagcctga tatcccccgc cccatcaaga tcaacctgct gttccccatc atctacttgc     2040

tgttctgggc cttcctgctg gtcttcagcc tgtggtcaga gccggtggtg tgtggcattg     2100

gcctggccat catgctgaca ggagtgcctg tctatttcct gggtgtttac tggcaacaca     2160

agcccaagtg tttcagtgac ttcattgagc tgctaaccct ggtgagccag aagatgtgtg     2220

tggtcgtgta ccccgaggtg gagcggggct cagggacaga ggaggctaat gaggacatgg     2280

aggagcagca gcagcccatg taccaaccca ctcccacgaa ggacaaggac gtggcggggc     2340

agccccagcc ctgaggacca ccattccctg gctactctct ccttcctccc ccttttatcc     2400

tacctccctg ccttggtcct gccaacacat gcgagtacac acacacccct ctctctgctt     2460

ttgtcaggca gtggtaggac tttggtgtgg gtggtgagaa attgtaaaca aaaactgaca     2520

ttcataccca aagaaccagc ctctcacccc agggtccatg tcccaggccc cactccagtg     2580

ctgcccacac tcccagctgc tggaggagag gggagatgcc aaggtgccct gcaggacctc     2640

cctccgggcc acaccctcag ctgcctcttc aggaaccgga gctcattact gccttccctc     2700

ccagggaggc cccttcagag aggagaggcc acaggagctg cattgtgggg ggacaggctc     2760

aagcaattct gtccccatca aggggtcagc tggagagacc caagacccta tctgttcacc     2820

agggacccaa aatccaaggg gatgcttccc tctgccctct ttcctgcccc tccccatcat     2880

acctgcaccc accccagcca gggctccctg tccagaattc ggttctcctc aggacgccaa     2940

ctcccagagc taaggaccaa ggagaagaac agcctctcca cccccaagcc aggcggttga     3000

ggaacatatt gagaaaggtt cagattgcag aaacccagcc ctgcccctgc ctcctgcatc     3060

cagcccccaa catggtgcca aagcttccag aagccaaaaa gcttctgatt tttaaggtag     3120

tgggcatctc tctcctaatg acgaagctgc tcagcaactc cacctgcccg ccgcaggaag     3180

gagcagtccc ctgctatccc tgcagccact cccagcacac ccgcacacag ccagcaccac     3240

cgcccccacc gtgcacttct cctctctggg ccttggcttg ggaccaggta cgaaggatcc     3300

ccaagccctt caggcctgag atcagagcca gatcagcctt aagtcacctc ccatccaaga     3360

acttggccta aaaatactcc cctatttcta accctcagga cggatctgat attaaatgcc     3420

ttccctggga ggaagggtgc tttccccctc cctagaggtg cccattccat accctgggag     3480

actgaggaga gcattggctg aagcccagtt cctttcccat ccatccccaa ctccaataat     3540

cccccactcc tcgcaggtct cagtgtcatg ctgtcttggg gcagggtgaa agggtagtgg     3600

cagcagggcg cccactctgg agatcctcaa aaaaggccct cctctgtggc tggcagcctc     3660

tgacctttcc ctgggcttca aaggaaggct atggagtttg ctgtgggccc tgcaaccttc     3720

ccagccactc ctgctgcact aaggacttag gatcctttta tcacaaatcg ggattctctc     3780

ccccaccccg aattctgtct gcttaaactg gaatacacag gagcccttcc tggcctggat     3840

ggtgtctccc agcttccccg cccagcttgc ccaccccata gttggtgaga tgccaagttt     3900

ggtctgagtt gtgacccctt cagagtagat gcccggcagg ctggggttgg cccctggagg     3960

gtcaggggac catcttctta ttccctcttt tctcattcct ccaacttcct cccctccttc     4020

aattattttt ttgtaaagtt gatgccttac tttttggata aatatttttg aagctggtat     4080

ttctatttct tttggatttt ttttaatgta aggttgtttt gggggatgga gttagaacct     4140

taatgataat ttctttcgtt tggtgtaggt tttagagatt tgttttgtgg agaggttttt     4200

ttcttttgat gtaataaaat ttaaaatgga aatgaaaaaa aaaaaaaaaa aaaaaaa        4257


<210>  1869
<211>  3195
<212>  DNA
<213>  homo sapiens

<400>  1869
gtagccacac ccacgccccc acaggcccgg cttccctgcc cagcggctcc aacctccagc       60

ctgggcaccc agacccagag ggctgctggg agggacatgc ctcacccctt ttgctccagc      120

tggaggggag ggagtctgtg ggagctggcc agagcgtggc agaaggcaga gaagtgaacg      180

ccccagcaaa agtgctcctc acatgggtca actgttccag tgtgcggtgg gccacccggg      240

ttcaagacat cttcacagct gggaagctcc tggccttggc cctgattatc atcatgggga      300

ttgtacagat atgcaaagga gagtacttct ggctggagcc aaagaatgca tttgagaatt      360

tccaggaacc tgacatcggc ctcgtcgcac tggctttcct tcagggctcc tttgcctatg      420

gaggctggaa ctttctgaat tacgtgactg aggagcttgt tgatccctac aagaaccttc      480

ccagagccat cttcatctcc atcccactgg tcacatttgt gtatgtcttt gccaatgtcg      540

cttatgtcac tgcaatgtcc ccccaggagc tgctggcatc caacgccgtc gctgtgactt      600

ttggagagaa gctcctagga gtcatggcct ggatcatgcc catttctgtt gccctgtcca      660

catttggagg agttaatggg tctctcttca cctcctctcg gctgttcttc gctggagccc      720

gagagggcca ccttcccagt gtgttggcca tgatccacgt gaagcgctgc accccaatcc      780

cagccctgct cttcacatgc atctccaccc tgctgatgct ggtcaccagc gacatgtaca      840

cactcatcaa ctatgtgggc ttcatcaact acctcttcta tggggtcacg gttgctggac      900

agatagtcct tcgctggaag aagcctgata tcccccgccc catcaagatc aacctgctgt      960

tccccatcat ctacttgctg ttctgggcct tcctgctggt cttcagcctg tggtcagagc     1020

cggtggtgtg tggcattggc ctggccatca tgctgacagg agtgcctgtc tatttcctgg     1080

gtgtttactg gcaacacaag cccaagtgtt tcagtgactt cattgagctg ctaaccctgg     1140

tgagccagaa gatgtgtgtg gtcgtgtacc ccgaggtgga gcggggctca gggacagagg     1200

aggctaatga ggacatggag gagcagcagc agcccatgta ccaacccact cccacgaagg     1260

acaaggacgt ggcggggcag ccccagccct gaggaccacc attccctggc tactctctcc     1320

ttcctccccc ttttatccta cctccctgcc ttggtcctgc caacacatgc gagtacacac     1380

acacccctct ctctgctttt gtcaggcagt ggtaggactt tggtgtgggt ggtgagaaat     1440

tgtaaacaaa aactgacatt catacccaaa gaaccagcct ctcaccccag ggtccatgtc     1500

ccaggcccca ctccagtgct gcccacactc ccagctgctg gaggagaggg gagatgccaa     1560

ggtgccctgc aggacctccc tccgggccac accctcagct gcctcttcag gaaccggagc     1620

tcattactgc cttccctccc agggaggccc cttcagagag gagaggccac aggagctgca     1680

ttgtgggggg acaggctcaa gcaattctgt ccccatcaag gggtcagctg gagagaccca     1740

agaccctatc tgttcaccag ggacccaaaa tccaagggga tgcttccctc tgccctcttt     1800

cctgcccctc cccatcatac ctgcacccac cccagccagg gctccctgtc cagaattcgg     1860

ttctcctcag gacgccaact cccagagcta aggaccaagg agaagaacag cctctccacc     1920

cccaagccag gcggttgagg aacatattga gaaaggttca gattgcagaa acccagccct     1980

gcccctgcct cctgcatcca gcccccaaca tggtgccaaa gcttccagaa gccaaaaagc     2040

ttctgatttt taaggtagtg ggcatctctc tcctaatgac gaagctgctc agcaactcca     2100

cctgcccgcc gcaggaagga gcagtcccct gctatccctg cagccactcc cagcacaccc     2160

gcacacagcc agcaccaccg cccccaccgt gcacttctcc tctctgggcc ttggcttggg     2220

accaggtacg aaggatcccc aagcccttca ggcctgagat cagagccaga tcagccttaa     2280

gtcacctccc atccaagaac ttggcctaaa aatactcccc tatttctaac cctcaggacg     2340

gatctgatat taaatgcctt ccctgggagg aagggtgctt tccccctccc tagaggtgcc     2400

cattccatac cctgggagac tgaggagagc attggctgaa gcccagttcc tttcccatcc     2460

atccccaact ccaataatcc cccactcctc gcaggtctca gtgtcatgct gtcttggggc     2520

agggtgaaag ggtagtggca gcagggcgcc cactctggag atcctcaaaa aaggccctcc     2580

tctgtggctg gcagcctctg acctttccct gggcttcaaa ggaaggctat ggagtttgct     2640

gtgggccctg caaccttccc agccactcct gctgcactaa ggacttagga tccttttatc     2700

acaaatcggg attctctccc ccaccccgaa ttctgtctgc ttaaactgga atacacagga     2760

gcccttcctg gcctggatgg tgtctcccag cttccccgcc cagcttgccc accccatagt     2820

tggtgagatg ccaagtttgg tctgagttgt gaccccttca gagtagatgc ccggcaggct     2880

ggggttggcc cctggagggt caggggacca tcttcttatt ccctcttttc tcattcctcc     2940

aacttcctcc cctccttcaa ttattttttt gtaaagttga tgccttactt tttggataaa     3000

tatttttgaa gctggtattt ctatttcttt tggatttttt ttaatgtaag gttgttttgg     3060

gggatggagt tagaacctta atgataattt ctttcgtttg gtgtaggttt tagagatttg     3120

ttttgtggag aggttttttt cttttgatgt aataaaattt aaaatggaaa tgaaaaaaaa     3180

aaaaaaaaaa aaaaa                                                      3195


<210>  1870
<211>  5913
<212>  DNA
<213>  homo sapiens

<400>  1870
gtggacgcag cgggctttgg aaaggcccca agttaatgag gcgtgcgccg gctgccgagc       60

gcctcttgga gctgggcttt cccccgcggt gcgggcgcca ggagccgcct tttccgctgg      120

gtgtcactcg ggggtgggga agatggccca ttcaaaagcg ccgcgagggg gcccggccag      180

tgcccttcag tgagcgctcg caagaggacg gcagaggccc ggcagctcgg agctccggga      240

ccttgtggcg catcaggacg cggctgtccc tctgccggga cccagagccg ccgccgccgc      300

tctgcctcct gcgtgttagc ctcctctgcg cgctccgggc aggcggccgt gggagccgct      360

ggggcgagga cggcgcgagg ctgctgctgc tgcccccggc ccgcgcggct ggaaacggag      420

aggccgagcc aagcggcggc ccctcttatg ctgggaggat gctggagagt agcggctgca      480

aagcgctgaa ggagggcgtg ctggagaagc gcagcgacgg gttgttgcag ctctggaaga      540

aaaagtgttg catcctcacc gaggaagggc tgctgcttat cccgcccaag cagctgcaac      600

accagcagca gcagcagcaa cagcagcagc agcagcagca acaacagccc gggcaggggc      660

cggccgagcc gtcccaaccc agtggccccg ctgtcgccag cctcgagccg ccggtcaagc      720

tcaaggaact gcacttctcc aacatgaaga ccgtggactg tgtggagcgc aagggcaagt      780

acatgtactt cactgtggtg atggcagagg gcaaggagat cgactttcgg tgcccgcaag      840

accagggctg gaacgccgag atcacgctgc agatggtgca gtacaagaat cgtcaggcca      900

tcctggcggt caaatccacg cggcagaagc agcagcacct ggtccagcag cagcccccct      960

cgcagccgca gccgcagccg cagctccagc cccaacccca gcctcagcct cagccgcaac     1020

cccagcccca atcacaaccc cagcctcagc cccaacccaa gcctcagccc cagcagctcc     1080

acccgtatcc gcatccacat ccacatccac actctcatcc tcactcgcac ccacaccctc     1140

acccgcaccc gcatccgcac caaataccgc acccacaccc acagccgcac tcgcagccgc     1200

acgggcaccg gcttctccgc agcacctcca actctgcctg aaaggggcag ctcccgggca     1260

agacaaggtt ttgaggactt gaggaagtgg gacgagcaca tttctattgt cttcacttgg     1320

atcaaaagca aaacagtctc tccgccccgc accagatcaa gtagtttgga catcacccta     1380

ctgaaaactt gcgattcttc ttagttttct gcatactttt catcacgatg caggaaacga     1440

tttcgagtca agaagacttt tatttatgaa cctttgaaag gatcgtcttg tatggtgaat     1500

tttctaggag cgatgatgta ctgtaatttt attttaatgt attttgattt atgattattt     1560

attagttttt ttttaaatgc ttgttctaag acatttctga atgtagacca ttttccaaaa     1620

aggaaacttt attttcaaaa acctaatccg tagtaattcc taatcttgga gaataaaaaa     1680

gggcggtgga ggggaaaaca ttaagaattt attcattatt tctcgagtac tttcagaaag     1740

tctgacactt tcattgttgt gccagctggt tgaaattaaa actctgatat tacttttttt     1800

gaggattttt atttttgttt ttgcttaaac atatagtttg tctagaagtt taaaaagcta     1860

aaagttaaaa atggtgtaat tatgaaaatc taacactcaa gatagtttct aaaaggaaat     1920

cagtagttaa ggatacctga tttcaaaata tttaaagcat aacctaactg atggtaggat     1980

gattgtatct tgaatatgtg gtagggccac atctattgta ggaaaacctt gcttttatca     2040

tctgtgtgta aagggcttaa taaggagaag aggccttttg actgatttgt gagtataaat     2100

gcatttgctg tttcatttca aaaatgttgt ggaggaaaag agtacattta acttgtataa     2160

gagaatattt gtactcctgt ccaggctgca ggacctttct tcgagagctt tgcacacttg     2220

acttgaacca cattttctga tccctttact ttgttttaga agcacactga aaaatctcgt     2280

tgtttaaagt acaatttgta aatatttcaa aggtctagga gtcataactt ttgttttcat     2340

actgaaaatg atgttgatca gagaaaccaa ctgttttgct tttcattgct ctgtgagaaa     2400

tttgaggatt ctgttttgct gttaggtaag ctaaactcag aaattgaaaa ggaaaagact     2460

ggataaacac aggattttca gtaagaaaac aaccccagtc ttgtcttaga agccacttgt     2520

tgaggagtct gttgggggaa aaaagaggat atgcttttaa aggtagaaca aaccttcttc     2580

tgtgttaaat caaaaggatg ttcaaaatcc accaggacag atgctacttg ggtttaaatg     2640

gagccataga tgatacaaag tcctcttggg gctgaaaatc acttcctatt tgcatggctt     2700

tactaactgg tttctgtttt ccattatctt tttcacagaa agtcttggtc agtatttttc     2760

cagcatttaa attgaaacgg tcagtattag accactgcta ggttatgtag tcaagaaata     2820

aaaatagaat tacatgctac agatgtcttt attctccttc catctagaaa ggagttccaa     2880

ggtcaaatta ctttttagtg caatagttaa atgacatttt gagatcataa ctcatatcca     2940

aaaagttgca gggaaaatta aaatagcttt cccctattaa gctaatggca aacaaaactt     3000

aagtggaccc ccacttccag tggttgttta ggttgcagtt gtgaaaatat gctgccaaca     3060

tttaaaaact tgtttcatat gtatatatgt atacacatat atgaatatgt atgtatatat     3120

acatatatga gaacatgtgt gtacacatat atgaatatgt atatatgtgt atgtatgtat     3180

atatgtatat gaaatgagag ccacatctaa agatttctta aatcaagttt ggttcagctt     3240

ccttagaact gtggctgtac tttttgagga gtacctcata gtactatatt tttaatgcat     3300

gcaaatcata atagctccaa atgaaccaca gttttttccc aatggaggat ttttttttaa     3360

ttcttgtact aaaaaaaaaa aatccatacc aaatattttt acaaattaag attgatgtag     3420

gttttaaaaa aggcatttgt atgttgttag cttacatatg gggctaggta atttcattgc     3480

ttaaaaagat gcgcctaggc tccctcttgg tggctggatt tctttttctt cgcccgtggt     3540

ggccatggtt cttaataggg ccaccggaat catggtttct tttttttttt ttttttttga     3600

gatggagtct cgccctgtga cccaggctgg agtgcagtgg cacgatctcg gctcactgca     3660

acctctgcct cctgggttca cgccattctc ctgtctcagc ctcctgagta gctgggacta     3720

caggtgaatg ccaccacgcc cggctgattt ttgtattttt agtagagatg gggtttcacc     3780

atagtggtca ggctgttctc gaactcctga cctcaggtga tccacctgcc ttggcctccc     3840

aaagtgctag gattacaggt gtgagccacc acacccggcc ccagaataat ggtttcttga     3900

ctttctgtag cccttgttcc ttagtctgct gtgatattta tgttgacctt tatcattttc     3960

tattctgaac ccctcttagc atttaatgtg aaatctaaga aattagaagt agaatggctt     4020

ttattgtttt gacacctttg aaattattat taataatttt tccagagcaa aaaagcaaac     4080

acgctcaata agactaaaca aaacaaaata taaatgtaca tcatttaatg tcccagtggc     4140

tctattctac ctgtaagaaa atgatacaaa accacctaag atattttgaa gcctgacaaa     4200

tcagcttcat ggaaaaaggt aaaaaatgca tttttcaacc gaaagggcag atccaataga     4260

agacccgctc cttaaataaa cataaaatgt aaaaagttgg aaaattaaga gtaatgttcc     4320

atctggaaac tgaacttttg tccttgaact tgtgttggca ccaagcctca tacacagtga     4380

gctcaataac tgttgggaca aaggaaggaa ggacaaaatg tgtaacttcc cagcatctgg     4440

gagatgctgt ctcttgcctc actgagtgtt ccttttcttt gctctcatgt cattccctga     4500

gaacaatgaa ttctgggaca ggctaaacat catgatgaag tttcttaaac agactttctt     4560

agtggaaatc catttagatc tgggtgtgct ctatggggag tgctgacgtc aaagagcaaa     4620

tgtctataag gggccctttt aaaatgaaca ttttcctcat tgagcaagct gggattctct     4680

aatgtagaaa tcaagccatc tttataattt cacttcagat gtttatgttt ttgttttttt     4740

tgtctccaat gatggtaaaa ataaaaacta cgcattactt aaaggagttt ccctcacatg     4800

taaacactgt taggaagtct ggattaagtt gaaagtcctg ttttaacttt ttttctctca     4860

tataccaaac actctgtatt tctcttaaag aagcccttta agagaaagcc ctaattttat     4920

atctgacagt aaagtttgct gcaagtgtat gagttcaaac acatcccttg ttttctgtcc     4980

ctaggggaaa agtcatgtag ttttagcttg gctccagtgt taatattata ttcagtagca     5040

gccttagaag agtggtctaa gacttgaacc tggagcaatt ttatagcaca gaatcctacg     5100

aagataggac tgtgaacatt tgttttcttt ttcgtgtgtg tcaaactaac tggtttttgc     5160

tttaccaata aaatgtcctc ggcagagtaa attttaaacg tgaaaattat agatcttgat     5220

attgaatcca tcagtgattc aagagataca cctatttgcc taaaacaacc taagatgtat     5280

tggttatgga atcatgtgtt ggataggttc ttaagacctg tttcctcaaa tcttgacaca     5340

gttttcaagg gtggcttatt gacttgcacg gttgggcaga taatccagat ttacctaaga     5400

ttgggtaaaa aagtcatctg tgactttgct ggcagggcat ttgctaagtg gagtacagga     5460

tctaaaaggg ttttcttaga aagggcaata ttgtccaatg aagtaagcag aaggactctg     5520

ggttagaagc atctgcacaa aaactggtga gacctactct ccactgctct gcagctggat     5580

ggctgatggc aggctgagca gtggggaagc aggttttaac aacagggagt ccttccaggt     5640

cactgtatat tgagaagaaa cataaaacta ttgtctgtta cattccgagg tcagccttct     5700

tcttaacgtt ttataatatg caaatgccag cttctggaaa gcaagtatca tcatgtacca     5760

aatgctttat acaccatcac attcatgaat tttttagcat ggtcagaact tgtgtaaata     5820

tgtctcttag atgattttgg ggagatgtga tttatttttc atattttcaa aatgcatttc     5880

atttcaaata aagttatcta ttgagacaac cga                                  5913


<210>  1871
<211>  6015
<212>  DNA
<213>  homo sapiens

<400>  1871
gtctggtgag gaaatcatca ccctaggacg taaaccctcc cgcccttctt tcagctctta       60

aaaaaagcct gccacgaaag tccctactgc gttgctgcga acgtagcttt gagaagctgg      120

cgcccagtga tggggcaaac agccatgccc ttccagcagc cgtgaaagcc ccaacagcaa      180

actgcctggg agcggggcag gtcaccaact tcgttgctcg aactccctgg gtgcccgccg      240

cggtggttac aaagggggtc aagagtgccg gacccagccg cgcggagccc accattgcgg      300

cccgaggggg acccgacggg ggcccgacgg tgtggcgtgg cgcaaggagc gcgcctgcct      360

tctctcgccg ccgggaacgg gctgcaccaa tggccagatt ccagcaagat tatggaagag      420

catagctaca tacaaaagga gctagattta caaaatggta gcttagagga agactctgtg      480

gtgcattctg ttgagaacga ttcccaaaac atgatggaga gcctcagccc aaagaaatac      540

tcttccagtc tgagatttaa agccaatgga gactattctg gctcctattt aaccctctca      600

caacctgtgc ctgcaaagag aagcccttct cctttgggaa ccagtgtcag aagcagcccc      660

tccttagcca aaatccaggg aagcaagcag ttctcttatg atggaactga caaaaatatt      720

cctatgaaac ctccaactcc tttactcaac actacatcct ccctcagtgg atatccactt      780

ggaagagcag actttgatca ttatactggc cgggacagtg aaagggcctt gaggctctca      840

gagaagcctc cctattccaa atatagctca aggcataaat cgcatgacaa tgtctactct      900

cttggagggc tggaaggtcg gaaggcatct ggctcgctcc tggccatgtg gaatggaagt      960

tccctgagtg atgctggccc gcctcctatc agcagatcgg gagccgcaag catgccttca     1020

agcccaaagc aagccaggaa aatgagcatt caggacagcc tggcgcttca acccaagtta     1080

actagacaca aggagcttgc atctgaaaac atcaatttga gaactaggaa gtactccagc     1140

agcagcctga gtcacatggg agcctacagc cgatcacttc ccaggttgta cagagccaca     1200

gagaaccagc tgacacctct cagcttgcct ccaagaaact ctctgggcaa ttccaaacga     1260

acaaaacttg gggaaaagga tctacctcat agcgtaatag acaatgacaa ttaccttaat     1320

ttttcttctt tgagctcagg ggctttaccc tataaaacct ctgcttctga aggcaatcct     1380

tatgtaagtt ctaccctcag tgtccctgcc agtccacgag tggctcggaa gatgcttctg     1440

gcctccacct cctcctgtgc ctctgatgac tttgatcagg cttcatatgt ggggacaaac     1500

ccgagtcatt cacttcttgc tggagagtca gacagagttt ttgcgaccag gaggaacttc     1560

tcttgtggat ctgtggaatt tgatgaggca gatttggaaa gcctcagaca ggcctcagga     1620

accccccagc ctgcccttcg ggaacggaaa agcagtatta gctccatttc aggacgtgat     1680

gacctgatgg attatcaccg gcggcagagg gaggaaagac tcagggagca ggaaatggag     1740

cgattggaga gacagcgtct ggagaccatc ctcagtctct gtgctgaata cacaaagcct     1800

gacagtcgct tatctactgg gaccaccgtg gaagatgtgc agaaaatcaa caaggagctt     1860

gagaagctgc agctctctga tgaggagtct gtgtttgagg aagccctcat gagccctgac     1920

acaagataca ggtgccaccg gaaagactcc ctccctgatg cagacttggc aagctgtggg     1980

agtctcagtc agagcagtgc cagcttcttt acccccagga gcaccaggaa tgatgaacta     2040

ctcagtgacc tcacccggac tcctccacca ccatcctcca cctttccgaa agcttccagc     2100

gagtcctctt atctaagtat cctaccaaag accccagagg gtataagtga agaacagaga     2160

tctcaggagt tggctgcaat ggaagaaacc cggatagtca ttctgaacaa cctcgaggaa     2220

cttaagcaaa aaatcaaaga cataaatgat cagatggatg agtctttcag agagttggat     2280

atggaatgtg ctcttttgga tggagaacag aaatctgaaa caactgaact tatgaaggag     2340

aaggagattt tggatcatct aaaccggaaa atagctgaac tggaaaagaa cattgttggt     2400

gaaaagacca aggatgctga cctgttggat gttgaaagca aacactttga agacctggag     2460

ttccagcagc ttgaacatga gagccgtcta gatgaagaaa aggagaactt gactcaacag     2520

ctcctgcgtg aagttgctga atatcaacgg aacatcgttt ctagaaagga aaaaatttct     2580

gcattgaaaa agcaagccaa tcacattgtt cagcaggctc agagagagca agatcatttt     2640

gtgaaagaaa agaataattt aataatgatg ttgcaaagag aaaaggagaa tctttgtaat     2700

ttggaaaaga aatactccag cctctctggg gggaaagggt ttcccgttaa ccccaatact     2760

ttaaaagagg gctatatcag tgtaaatgag attaatgagc cgtgtggcaa ttccacgaat     2820

ctatcccctt ccactcagtt tcctgctgat gctgatgctg ttgccactga gcctgccaca     2880

gctgtgctgg cgagccagcc acagagtaaa gagcacttta gaagtctgga agaaaggaaa     2940

aaacagcata aagaaggcct ctatctgagt gatactttgc ctcgaaagaa aaccacatct     3000

tccatctccc cacatttcag cagtgctact atggggagaa gcatcacccc aaaggcccat     3060

ctgcccctag gacagagtaa cagctgtgga agtgtgctcc ctccctcact ggcagccatg     3120

gccaaagact cagaatctcg gaggatgctc agaggttata atcaccaaca gatgagtgaa     3180

ggacacaggc agaaatctga attttataac cgcacagcat ctgaatcaaa tgtctacttg     3240

aatagtttcc attatccaga tcacagctac aaggaccagg cctttgatac tctgagcctc     3300

gatagctctg atagcatgga gaccagcatc tctgcttgct caccagacaa catctctagt     3360

gccagcactt caaatattgc tagaatagaa gaaatggaga gacttttgaa gcaggctcat     3420

gcagaaaaga cgcggctgct cgaatccagg gaacgggaaa tggaagccaa aaaacgagcc     3480

ctggaagaag aaaaacgacg ccgggaaatc ctggaaaaac gattacagga agaaactagc     3540

cagaggcaga agttaataga aaaggaagta aaaataaggg agagacaaag ggcacaggct     3600

cgtcctttga cacgctacct gcctgtccgg aaggaagact ttgatttgcg gagccatgta     3660

gagactgctg gccacaatat tgacacctgt taccatgtat caatcacaga gaagacctgc     3720

cgaggattcc tcatcaaaat gggtgggaaa attaaaacgt ggaaaaaacg ttggtttgtt     3780

tttgatcgga acaagcgaac attctcttat tatgcagaca agcatgaaac taaattgaaa     3840

ggagtaatat actttcaagc cattgaagaa gtctattatg atcacctcaa gaatgctaat     3900

aagagtccta atccgttact cacctttagc gtcaagactc atgacagaat ctattatatg     3960

gtagccccat cgccagaagc catgcggatc tggatggatg ttatagttac gggggcagaa     4020

ggttacactc acttcttgtt gtagtgaact gaggcaacag tccacttcag ggcagacggc     4080

aataatctct tacaagaatg aagccatatt caaccccaga tgagaaaacc caacagatcc     4140

atcccttgag ctgtaaacac tcagaactcc tttcatatca agacaagtta tttgtaaaaa     4200

ataaagaagg ggttttaata caaaccttca taataaatag caaaataatt gaagcttcca     4260

tgagaaagaa aacactattt tgataaattg gatcacttat aggaacattt ctaataaact     4320

gtttttaatc agttgtcgga tttggtgaaa taaactaaac aggttacaga atatctgtat     4380

gtacttggaa atacagaata actttatcac ccaaatcact ggcattgaca ttattggtaa     4440

tcaactggct ttttttaaaa aaggtagcat tttgttgaca gttattttgt aaacataagc     4500

aaataagggc ttggagggaa atacatttta ggaggagttt tgccttaatt ttttaagtac     4560

tgcaccaaaa ccaaagagct gacctgactt ctgtggaaca gtagtaactg caagtgatga     4620

actgcatttc gtattgttct gtatatttca aaatggtatt ttgatgccat caaatgccca     4680

ggaaattgac tttgcagtgt caccactggt gtaagctact atatatgtat atatatatgt     4740

agtaaaccac tttttgtaaa agaagaaaga gcaaaaagct gtgtgtttta gaaaaaaaag     4800

ccaggttacg caacaggcat tctgtcatgt tgaacaattt taaataaaga gaatatctgg     4860

tgttaggagc ttgttttgct gaagatttct ccattcctgg tgctgagaat aaaggcaacc     4920

agtagccaat gtcctttaga ttgtctgatt tctttttgtt gtggagcaca cctgctaact     4980

gctccctcaa cataactatg aaatcatagc tctgttttca ccaaagaaca gaccaattaa     5040

catacttatt tgcagaagtg gtgtagttct ataaaacggc aaatgaagtt caacttaata     5100

ttctctataa tgtattattt tattttattt tttacaatta gccttttttt tagttaattt     5160

ttgtcaaatg aaacgacttc aggcaagtct cttttataat ggtttttcaa gtgccattta     5220

ttctagttta tcatgttttg catgtttgaa agtatgaatg tgctctttcc taaaacatgg     5280

caaatgaata gatgtagaga ataacaatat tacttacaag atgaaatgat tagattagaa     5340

gtgtcccttt attaaacttt gtcagcctga ctgggtacaa ttcttttgtt aatttgcagt     5400

gtggtttgta tacacgtata cgtgttatca ataataagat tttgcaactg gatgacacaa     5460

gattttactt gaacagtgaa ggacaaaaat catgattgtg gaagatattt ttaaaatctg     5520

attttgcagc gatcactttt aaaccctgta gtgatgtaag actaaaatat aattgctaag     5580

attttgttgg ttaatgtaaa gatatgactt ttctgcactg tactctcttc ataggattgt     5640

aaaggtgttc taatccaatt gcatgatgta gtaagcctct taaatatgtg tgttaaatat     5700

attgagtttg gattaaaatg ttgacatgat ttcacatttg aaaataaact catctcttat     5760

tttgaagtta cctatctgta gtatgatgga ggatgaatta atcgcaaatg acagttgtag     5820

aaactatgta aagtttgttg tgtgctaaca ttatgatttg tagtgtataa actgaagtat     5880

tccaatagaa gtatctctgg ttacatccta ttgcttacaa aatgaaatga accctgaaaa     5940

actctgacat catattgttg tctgtttaca cagatacatt tattgctggg gattgcaaaa     6000

aaaaaaaaaa aaaaa                                                      6015


<210>  1872
<211>  5957
<212>  DNA
<213>  homo sapiens

<400>  1872
aagcaagttg ctgcctgtga ccacagtctg cagaggccag agagagcagg aaaggaaatg       60

gaaaggaacc tcaccttcat gcttggggaa aaggagaaac ctgtgttaat gtgtcttccc      120

aacatcccac tctcttcagc aatcgctgga acagccatgg gccatccctg ctgagtcagg      180

aaagaagctg agggaagagt cgggattgaa aagcagcaga caaggctggc actgatccca      240

gtttatcctt tgagattcag cagaagatcc tgatggagga ggaggatacc aagagagagg      300

tgcccaagga agatggagtt ggtgatgtgc aacatttcga ttccagcaag attatggaag      360

agcatagcta catacaaaag gagctagatt tacaaaatgg tagcttagag gaagactctg      420

tggtgcattc tgttgagaac gattcccaaa acatgatgga gagcctcagc ccaaagaaat      480

actcttccag tctgagattt aaagccaatg gagactattc tggctcctat ttaaccctct      540

cacaacctgt gcctgcaaag agaagccctt ctcctttggg aaccagtgtc agaagcagcc      600

cctccttagc caaaatccag ggaagcaagc agttctctta tgatggaact gacaaaaata      660

ttcctatgaa acctccaact cctttactca acactacatc ctccctcagt ggatatccac      720

ttggaagagc agactttgat cattatactg gccgggacag tgaaagggcc ttgaggctct      780

cagagaagcc tccctattcc aaatatagct caaggcataa atcgcatgac aatgtctact      840

ctcttggagg gctggaaggt cggaaggcat ctggctcgct cctggccatg tggaatggaa      900

gttccctgag tgatgctggc ccgcctccta tcagcagatc gggagccgca agcatgcctt      960

caagcccaaa gcaagccagg aaaatgagca ttcaggacag cctggcgctt caacccaagt     1020

taactagaca caaggagctt gcatctgaaa acatcaattt gagaactagg aagtactcca     1080

gcagcagcct gagtcacatg ggagcctaca gccgatcact tcccaggttg tacagagcca     1140

cagagaacca gctgacacct ctcagcttgc ctccaagaaa ctctctgggc aattccaaac     1200

gaacaaaact tggggaaaag gatctacctc atagcgtaat agacaatgac aattacctta     1260

atttttcttc tttgagctca ggggctttac cctataaaac ctctgcttct gaaggcaatc     1320

cttatgtaag ttctaccctc agtgtccctg ccagtccacg agtggctcgg aagatgcttc     1380

tggcctccac ctcctcctgt gcctctgatg actttgatca ggcttcatat gtggggacaa     1440

acccgagtca ttcacttctt gctggagagt cagacagagt ttttgcgacc aggaggaact     1500

tctcttgtgg atctgtggaa tttgatgagg cagatttgga aagcctcaga caggcctcag     1560

gaacccccca gcctgccctt cgggaacgga aaagcagtat tagctccatt tcaggacgtg     1620

atgacctgat ggattatcac cggcggcaga gggaggaaag actcagggag caggaaatgg     1680

agcgattgga gagacagcgt ctggagacca tcctcagtct ctgtgctgaa tacacaaagc     1740

ctgacagtcg cttatctact gggaccaccg tggaagatgt gcagaaaatc aacaaggagc     1800

ttgagaagct gcagctctct gatgaggagt ctgtgtttga ggaagccctc atgagccctg     1860

acacaagata caggtgccac cggaaagact ccctccctga tgcagacttg gcaagctgtg     1920

ggagtctcag tcagagcagt gccagcttct ttacccccag gagcaccagg aatgatgaac     1980

tactcagtga cctcacccgg actcctccac caccatcctc cacctttccg aaagcttcca     2040

gcgagtcctc ttatctaagt atcctaccaa agaccccaga gggtataagt gaagaacaga     2100

gatctcagga gttggctgca atggaagaaa cccggatagt cattctgaac aacctcgagg     2160

aacttaagca aaaaatcaaa gacataaatg atcagatgga tgagtctttc agagagttgg     2220

atatggaatg tgctcttttg gatggagaac agaaatctga aacaactgaa cttatgaagg     2280

agaaggagat tttggatcat ctaaaccgga aaatagctga actggaaaag aacattgttg     2340

gtgaaaagac caaggatgct gacctgttgg atgttgaaag caaacacttt gaagacctgg     2400

agttccagca gcttgaacat gagagccgtc tagatgaaga aaaggagaac ttgactcaac     2460

agctcctgcg tgaagttgct gaatatcaac ggaacatcgt ttctagaaag gaaaaaattt     2520

ctgcattgaa aaagcaagcc aatcacattg ttcagcaggc tcagagagag caagatcatt     2580

ttgtgaaaga aaagaataat ttaataatga tgttgcaaag agaaaaggag aatctttgta     2640

atttggaaaa gaaatactcc agcctctctg gggggaaagg gtttcccgtt aaccccaata     2700

ctttaaaaga gggctatatc agtgtaaatg agattaatga gccgtgtggc aattccacga     2760

atctatcccc ttccactcag tttcctgctg atgctgatgc tgttgccact gagcctgcca     2820

cagctgtgct ggcgagccag ccacagagta aagagcactt tagaagtctg gaagaaagga     2880

aaaaacagca taaagaaggc ctctatctga gtgatacttt gcctcgaaag aaaaccacat     2940

cttccatctc cccacatttc agcagtgcta ctatggggag aagcatcacc ccaaaggccc     3000

atctgcccct aggacagagt aacagctgtg gaagtgtgct ccctccctca ctggcagcca     3060

tggccaaaga ctcagaatct cggaggatgc tcagaggtta taatcaccaa cagatgagtg     3120

aaggacacag gcagaaatct gaattttata accgcacagc atctgaatca aatgtctact     3180

tgaatagttt ccattatcca gatcacagct acaaggacca ggcctttgat actctgagcc     3240

tcgatagctc tgatagcatg gagaccagca tctctgcttg ctcaccagac aacatctcta     3300

gtgccagcac ttcaaatatt gctagaatag aagaaatgga gagacttttg aagcaggctc     3360

atgcagaaaa gacgcggctg ctcgaatcca gggaacggga aatggaagcc aaaaaacgag     3420

ccctggaaga agaaaaacga cgccgggaaa tcctggaaaa acgattacag gaagaaacta     3480

gccagaggca gaagttaata gaaaaggaag taaaaataag ggagagacaa agggcacagg     3540

ctcgtccttt gacacgctac ctgcctgtcc ggaaggaaga ctttgatttg cggagccatg     3600

tagagactgc tggccacaat attgacacct gttaccatgt atcaatcaca gagaagacct     3660

gccgaggatt cctcatcaaa atgggtggga aaattaaaac gtggaaaaaa cgttggtttg     3720

tttttgatcg gaacaagcga acattctctt attatgcaga caagcatgaa actaaattga     3780

aaggagtaat atactttcaa gccattgaag aagtctatta tgatcacctc aagaatgcta     3840

ataagagtcc taatccgtta ctcaccttta gcgtcaagac tcatgacaga atctattata     3900

tggtagcccc atcgccagaa gccatgcgga tctggatgga tgttatagtt acgggggcag     3960

aaggttacac tcacttcttg ttgtagtgaa ctgaggcaac agtccacttc agggcagacg     4020

gcaataatct cttacaagaa tgaagccata ttcaacccca gatgagaaaa cccaacagat     4080

ccatcccttg agctgtaaac actcagaact cctttcatat caagacaagt tatttgtaaa     4140

aaataaagaa ggggttttaa tacaaacctt cataataaat agcaaaataa ttgaagcttc     4200

catgagaaag aaaacactat tttgataaat tggatcactt ataggaacat ttctaataaa     4260

ctgtttttaa tcagttgtcg gatttggtga aataaactaa acaggttaca gaatatctgt     4320

atgtacttgg aaatacagaa taactttatc acccaaatca ctggcattga cattattggt     4380

aatcaactgg ctttttttaa aaaaggtagc attttgttga cagttatttt gtaaacataa     4440

gcaaataagg gcttggaggg aaatacattt taggaggagt tttgccttaa ttttttaagt     4500

actgcaccaa aaccaaagag ctgacctgac ttctgtggaa cagtagtaac tgcaagtgat     4560

gaactgcatt tcgtattgtt ctgtatattt caaaatggta ttttgatgcc atcaaatgcc     4620

caggaaattg actttgcagt gtcaccactg gtgtaagcta ctatatatgt atatatatat     4680

gtagtaaacc actttttgta aaagaagaaa gagcaaaaag ctgtgtgttt tagaaaaaaa     4740

agccaggtta cgcaacaggc attctgtcat gttgaacaat tttaaataaa gagaatatct     4800

ggtgttagga gcttgttttg ctgaagattt ctccattcct ggtgctgaga ataaaggcaa     4860

ccagtagcca atgtccttta gattgtctga tttctttttg ttgtggagca cacctgctaa     4920

ctgctccctc aacataacta tgaaatcata gctctgtttt caccaaagaa cagaccaatt     4980

aacatactta tttgcagaag tggtgtagtt ctataaaacg gcaaatgaag ttcaacttaa     5040

tattctctat aatgtattat tttattttat tttttacaat tagccttttt tttagttaat     5100

ttttgtcaaa tgaaacgact tcaggcaagt ctcttttata atggtttttc aagtgccatt     5160

tattctagtt tatcatgttt tgcatgtttg aaagtatgaa tgtgctcttt cctaaaacat     5220

ggcaaatgaa tagatgtaga gaataacaat attacttaca agatgaaatg attagattag     5280

aagtgtccct ttattaaact ttgtcagcct gactgggtac aattcttttg ttaatttgca     5340

gtgtggtttg tatacacgta tacgtgttat caataataag attttgcaac tggatgacac     5400

aagattttac ttgaacagtg aaggacaaaa atcatgattg tggaagatat ttttaaaatc     5460

tgattttgca gcgatcactt ttaaaccctg tagtgatgta agactaaaat ataattgcta     5520

agattttgtt ggttaatgta aagatatgac ttttctgcac tgtactctct tcataggatt     5580

gtaaaggtgt tctaatccaa ttgcatgatg tagtaagcct cttaaatatg tgtgttaaat     5640

atattgagtt tggattaaaa tgttgacatg atttcacatt tgaaaataaa ctcatctctt     5700

attttgaagt tacctatctg tagtatgatg gaggatgaat taatcgcaaa tgacagttgt     5760

agaaactatg taaagtttgt tgtgtgctaa cattatgatt tgtagtgtat aaactgaagt     5820

attccaatag aagtatctct ggttacatcc tattgcttac aaaatgaaat gaaccctgaa     5880

aaactctgac atcatattgt tgtctgttta cacagataca tttattgctg gggattgcaa     5940

aaaaaaaaaa aaaaaaa                                                    5957


<210>  1873
<211>  3867
<212>  DNA
<213>  homo sapiens

<400>  1873
ggtgcatgga aggatttttt tgcagatgag agggaatcgg gattaataag gggaacttgc       60

gaccccgcgt ctcgagctgg ccgtccctgg ccttgggctc accggggcct cggcccccaa      120

gacctgacaa ctggagtccg cgaccacaac tgggagaact acaactccca ggatgccgcg      180

caccgcctgc gcccgagctc gacgaggcct cgcacagcca atgggagggt ccgggggcgg      240

gaactcggag tacgtgcgtt gtgacgcacc gacggcgacg tcggggtttg tgtgcgcgag      300

aggccgccga taaaggttgg gtgcctcgcg ccgggggccg ttgggaggga gtgcgcccct      360

gccccccctc cccggtcccc acagctgcac cgccgctgcc ggggccccac cttcccgtcg      420

acccccgcgg gaaggtcctg gggctgccac cctcgttccc ccgattgggg ccgcagaggc      480

atgatcaagg acagggttgc ctgccaagaa caggagggga gaggaggggc tggaggtttc      540

aggagaaaga agcatgtcag gtgtgatggt cggctcccac gcggacatgg cgccggcctc      600

tactgcggag ggggccgggg agaagccagg ccctgcggcc cctgccccgg cggcccagta      660

cgaatgtggg gagtgtggca agtcattccg gtggtcgtcc cggctcctgc accaccagcg      720

cacgcacaca ggcgagcggc cctacaagtg cccagactgc cccaaggctt tcaaaggctc      780

ctcggccctg ctctaccacc agcgaggcca cacgggcgag cggccctacc agtgccccga      840

ctgtcccaag gccttcaagc gctcctctct gctgcagatc caccgtagcg tgcacaccgg      900

cctgcgggcc ttcatctgcg gccagtgcgg cctggccttc aagtggtcgt cccactacca      960

gtaccactta aggcagcaca caggcgagcg cccctacccg tgcccggact gccccaaggc     1020

cttcaagaac tcgtccagcc tgcggcgcca ccgccacgtg cacaccggcg agcggcccta     1080

cacctgtgga gtctgcggga agagcttcac gcagagcacc aacctgcggc agcaccagcg     1140

cgtgcacacg ggcgagcggc ccttccgctg cccgctctgc cccaagacct tcacccactc     1200

ctccaacctg ctgctgcacc agcgcacgca cggcgccgcc cccgccccgg gtaccgcctc     1260

cgcggccccg cccccccagt cccgggagcc cggcaaggtc ttcgtgtgcg acgcctacct     1320

gcagcggcac ctccagcccc acagcccgcc cgcgcctccc gccccgccgc ccccgccccc     1380

gcccgtggtg cctgagctct ttttggcggc ggcggagacc acggtggagc tggtgtaccg     1440

ctgcgatggc tgcgagcagg gattcagcag cgaggagctg ctcctggagc accagccgtg     1500

ccccgggccc gatgcggcgc cccagcccca ggaggcaccc gccgaggcgc ccaaggccga     1560

ccagccaccg tcccctctgc cgcagccccc tcctcccgcc gccgcccccg cgcctggctt     1620

tgcctgtctg ccctgcggca agtccttccg gacggtggct gggctctccc gccaccagca     1680

cagccacggg gctgccggcg ggcaagcgtt ccgctgcggc agctgcgacg gctccttccc     1740

gcagctggcc agcctcctgg cgcatcagca gtgccacgtg gaagaggccg cggccgggcg     1800

cccgcccccg caggctgagg ctgcggaggt gacctgcccc caggaaccgc tggcgcctgc     1860

cgcccccgtc ccgccgccac ccccgtccgc ccccgcttct gcggagcggc cctacaaatg     1920

tgccgagtgc ggcaagtcct tcaagggctc ctccgggctg cgctaccacc tgcgggacca     1980

cacgggcgag cggccctacc agtgtggcga gtgcggcaag gccttcaagc gctcctccct     2040

gctggccatc caccagcggg tgcacacggg cctgcgggcc ttcacctgtg gccagtgcgg     2100

cctcaccttc aagtggtcgt cccactacca gtaccacctg cggctgcact ctggcgagcg     2160

gccctacgcc tgcggggagt gtggcaaggc cttccgcaac acgtcgtgcc tgcgtcgcca     2220

ccgccacgtg cacactggcg agaggcccca cgcctgcggt gtctgcggca agagcttcgc     2280

gcagacctcc aacctgcggc agcaccagcg cgtgcacacg ggcgagcggc ccttccgctg     2340

cccgctctgc cccaagacct tcacccactc ctccaacctg ctgctgcacc agcgcacgca     2400

ctcggcggag cgccccttca cctgccccat ctgcggtcgc ggcttcgtta tggccgccta     2460

tctgcagcgg cacctgagga cgcacgcccc ggccaacacg cctcccagca ccacagcccc     2520

tgccgccggc ccccagcccc ctgctccact ggctgctgcg cgggccccgc cagccaccca     2580

agatgtccac gtcctgcccc acctccaggc cacgctctcc ctcgaggtgg cggggggcac     2640

ggcccaggcc ccgagcttgg ggccagcagc gcccaactct cagacgttcc tcctggtgca     2700

aactgcccag ggcctccagc tgatccccag cagcgtgcag ccccctacac ctccgccccc     2760

tcccgcacct cccaagctca tcctgctgcc ctcctccagt gctggggctg ggggcggccg     2820

tgcaaggcag ggcccgcggg cagtggggaa agcgggccag ggggcgggag tggtctggct     2880

gccaggccct gggggtctag gggtgcaggg agcggccagc gctggggcca gcgggacagg     2940

gcagagcctc atcgttctgc agaatgtggg gggtggggag gcagggccac aggaaatgag     3000

tggggtgcag ctccagcccc tccgaccagc cccagaagta accacggtcc agctccagcc     3060

agcgcaggag gtgaccacag tccagctcca gccagcacag gaagtaacca cggtccagct     3120

ccagccagca caggaggtga ccacggtcca gctccagccc gtggccggcc agctctccaa     3180

ttccagtggg ggagctgtgg ctactgaggc acccaacctg ctggttgttc agagcggggc     3240

agctgaggag ttgctcactg gcccgggccc cggggaggcg ggggatggcg aggccagcac     3300

tggtgtggtc caggatgtcc tctttgagac actccagacg gacgagggct tgcagagcgt     3360

gctggtgctg agcggggccg atggcgaaca gactcgactc tgcgtacagg aggtagaaac     3420

acttcctcct gggctgacgg agccgcctgc caccggccca cccggacaga aactcctcat     3480

catccgcagc gccccagcca ctgagctgct ggacagcagc aacactggag gaggcaccgc     3540

cacgctgcag ctcctggccc caccgccgtc aggcccagcc tcgggccccg cggggctccc     3600

cggggctcca gcctcccaga tggtgcaagt ggtccccgca ggagctgggc ctggtgttat     3660

gacccctcag ggcctgccct ccatccagat tgtccagact ctacccgcag tccagctggt     3720

gcacacgttt tgaggagagg cagtgattcc cctcccgccc cgcacagaga ccccgactca     3780

ctgccagccg gggcggggca gggtgccgca ggctgggctt gctaataaag acccgagtct     3840

ccccgccaaa aaaaaaaaaa aaaaaaa                                         3867


<210>  1874
<211>  3867
<212>  DNA
<213>  homo sapiens

<400>  1874
ggtgcatgga aggatttttt tgcagatgag agggaatcgg gattaataag gggaacttgc       60

gaccccgcgt ctcgagctgg ccgtccctgg ccttgggctc accggggcct cggcccccaa      120

gacctgacaa ctggagtccg cgaccacaac tgggagaact acaactccca ggatgccgcg      180

caccgcctgc gcccgagctc gacgaggcct cgcacagcca atgggagggt ccgggggcgg      240

gaactcggag tacgtgcgtt gtgacgcacc gacggcgacg tcggggtttg tgtgcgcgag      300

aggccgccga taaaggttgg gtgcctcgcg ccgggggccg ttgggaggga gtgcgcccct      360

gccccccctc cccggtcccc acagctgcac cgccgctgcc ggggccccac cttcccgtcg      420

acccccgcgg gaaggtcctg gggctgccac cctcgttccc ccgattgggg ccgcagaggc      480

atgatcaagg acagggttgc ctgccaagaa caggagggga gaggaggggc tggaggtttc      540

aggagaaaga agcatgtcag gtgtgatggt cggctcccac gcggacatgg cgccggcctc      600

tactgcggag ggggccgggg agaagccagg ccctgcggcc cctgccccgg cggcccagta      660

cgaatgtggg gagtgtggca agtcattccg gtggtcgtcc cggctcctgc accaccagcg      720

cacgcacaca ggcgagcggc cctacaagtg cccagactgc cccaaggctt tcaaaggctc      780

ctcggccctg ctctaccacc agcgaggcca cacgggcgag cggccctacc agtgccccga      840

ctgtcccaag gccttcaagc gctcctctct gctgcagatc caccgtagcg tgcacaccgg      900

cctgcgggcc ttcatctgcg gccagtgcgg cctggccttc aagtggtcgt cccactacca      960

gtaccactta aggcagcaca caggcgagcg cccctacccg tgcccggact gccccaaggc     1020

cttcaagaac tcgtccagcc tgcggcgcca ccgccacgtg cacaccggcg agcggcccta     1080

cacctgtgga gtctgcggga agagcttcac gcagagcacc aacctgcggc agcaccagcg     1140

cgtgcacacg ggcgagcggc ccttccgctg cccgctctgc cccaagacct tcacccactc     1200

ctccaacctg ctgctgcacc agcgcacgca cggcgccgcc cccgccccgg gtaccgcctc     1260

cgcggccccg cccccccagt cccgggagcc cggcaaggtc ttcgtgtgcg acgcctacct     1320

gcagcggcac ctccagcccc acagcccgcc cgcgcctccc gccccgccgc ccccgccccc     1380

gcccgtggtg cctgagctct ttttggcggc ggcggagacc acggtggagc tggtgtaccg     1440

ctgcgatggc tgcgagcagg gattcagcag cgaggagctg ctcctggagc accagccgtg     1500

ccccgggccc gatgcggcgc cccagcccca ggaggcaccc gccgaggcgc ccaaggccga     1560

ccagccaccg tcccctctgc cgcagccccc tcctcccgcc gccgcccccg cgcctggctt     1620

tgcctgtctg ccctgcggca agtccttccg gacggtggct gggctctccc gccaccagca     1680

cagccacggg gctgccggcg ggcaagcgtt ccgctgcggc agctgcgacg gctccttccc     1740

gcagctggcc agcctcctgg cgcatcagca gtgccacgtg gaagaggccg cggccgggcg     1800

cccgcccccg caggctgagg ctgcggaggt gacctgcccc caggaaccgc tggcgcctgc     1860

cgcccccgtc ccgccgccac ccccgtccgc ccccgcttct gcggagcggc cctacaaatg     1920

tgccgagtgc ggcaagtcct tcaagggctc ctccgggctg cgctaccacc tgcgggacca     1980

cacgggcgag cggccctacc agtgtggcga gtgcggcaag gccttcaagc gctcctccct     2040

gctggccatc caccagcggg tgcacacggg cctgcgggcc ttcacctgtg gccagtgcgg     2100

cctcaccttc aagtggtcgt cccactacca gtaccacctg cggctgcact ctggcgagcg     2160

gccctacgcc tgcggggagt gtggcaaggc cttccgcaac acgtcgtgcc tgcgtcgcca     2220

ccgccacgtg cacactggcg agaggcccca cgcctgcggt gtctgcggca agagcttcgc     2280

gcagacctcc aacctgcggc agcaccagcg cgtgcacacg ggcgagcggc ccttccgctg     2340

cccgctctgc cccaagacct tcacccactc ctccaacctg ctgctgcacc agcgcacgca     2400

ctcggcggag cgccccttca cctgccccat ctgcggtcgc ggcttcgtta tggccgccta     2460

tctgcagcgg cacctgagga cgcacgcccc ggccaacacg cctcccagca ccacagcccc     2520

tgccgccggc ccccagcccc ctgctccact ggctgctgcg cgggccccgc cagccaccca     2580

agatgtccac gtcctgcccc acctccaggc cacgctctcc ctcgaggtgg cggggggcac     2640

ggcccaggcc ccgagcttgg ggccagcagc gcccaactct cagacgttcc tcctggtgca     2700

aactgcccag ggcctccagc tgatccccag cagcgtgcag ccccctacac ctccgccccc     2760

tcccgcacct cccaagctca tcctgctgcc ctcctccagt gctggggctg ggggcggccg     2820

tgcaaggcag ggcccgcggg cagtggggaa agcgggccag ggggcgggag tggtctggct     2880

gccaggccct gggggtctag gggtgcaggg agcggccagc gctggggcca gcgggacagg     2940

gcagagcctc atcgttctgc agaatgtggg gggtggggag gcagggccac aggaaatgag     3000

tggggtgcag ctccagcccc tccgaccagc cccagaagta accacggtcc agctccagcc     3060

agcgcaggag gtgaccacag tccagctcca gccagcacag gaagtaacca cggtccagct     3120

ccagccagca caggaggtga ccacggtcca gctccagccc gtggccggcc agctctccaa     3180

ttccagtggg ggagctgtgg ctactgaggc acccaacctg ctggttgttc agagcggggc     3240

agctgaggag ttgctcactg gcccgggccc cggggaggcg ggggatggcg aggccagcac     3300

tggtgtggtc caggatgtcc tctttgagac actccagacg gacgagggct tgcagagcgt     3360

gctggtgctg agcggggccg atggcgaaca gactcgactc tgcgtacagg aggtagaaac     3420

acttcctcct gggctgacgg agccgcctgc caccggccca cccggacaga aactcctcat     3480

catccgcagc gccccagcca ctgagctgct ggacagcagc aacactggag gaggcaccgc     3540

cacgctgcag ctcctggccc caccgccgtc aggcccagcc tcgggccccg cggggctccc     3600

cggggctcca gcctcccaga tggtgcaagt ggtccccgca ggagctgggc ctggtgttat     3660

gacccctcag ggcctgccct ccatccagat tgtccagact ctacccgcag tccagctggt     3720

gcacacgttt tgaggagagg cagtgattcc cctcccgccc cgcacagaga ccccgactca     3780

ctgccagccg gggcggggca gggtgccgca ggctgggctt gctaataaag acccgagtct     3840

ccccgccaaa aaaaaaaaaa aaaaaaa                                         3867


<210>  1875
<211>  4265
<212>  DNA
<213>  homo sapiens

<400>  1875
ggcggtccgg gcgggtgact ggcggcgggc gccgcggtcg ggctggctgc cgggcagcat       60

ggaggagctg agcagcgtgg gcgagcaggt cttcgccgcc gagtgcatcc tgagcaagcg      120

gctccgcaag ggcaagctgg agtacctggt caagtggcgc ggctggtcct ccaaacataa      180

cagctgggag ccggaggaga acatcctgga cccgaggctg ctcctggcct tccagaagaa      240

ggaacatgag aaggaggtgc agaaccggaa gagaggcaag aggccgagag gccggccaag      300

gaagctcact gccatgtcct cctgcagccg gcgctccaag ctcaaggaac ccgatgctcc      360

ctccaaatcc aagtccagca gttcctcctc ttcctccacg tcatcctcct cttcctcaga      420

tgaagaggat gacagtgact tagatgctaa gaggggtccc cggggccgcg agacccaccc      480

agtgccgcag aagaaggccc agatcctggt ggccaaaccc gagctgaagg atcccatccg      540

gaagaagcgg ggacgaaagc ccctgccccc agagcaaaag gcaacccgaa gacccgtgag      600

cctggccaag gtgctgaaga ccgcccggaa ggatctgggg gccccggcca gcaagctgcc      660

ccctccactc agcgcccccg ttgcaggcct ggcagctctg aaggcccacg ccaaggaggc      720

ctgtggcggc cccagtgcca tggccacccc agagaacctg gccagcctaa tgaagggcat      780

ggccagtagc cccggccggg gtggcatcag ctggcagagc tccatcgtgc actacatgaa      840

ccggatgacc cagagccagg cccaggctgc cagcaggttg gcgctgaagg cccaggccac      900

caacaagtgc ggcctcgggc tggacctgaa ggtgaggacg cagaaagggg agctgggaat      960

gagccctcca ggaagcaaaa tcccgaaggc ccccagcggt ggggctgtgg agcagaaagt     1020

ggggaacaca gggggccccc cgcacaccca tggtgccagc agggtgcctg ctgggtgccc     1080

aggcccccag ccagcaccca cccaggagct gagcctccag gtcttggact tgcagagtgt     1140

caagaatggc atgcccgggg tgggtctcct tgcccgccac gccaccgcca ccaagggtgt     1200

cccggccacc aacccagccc ctgggaaggg cactgggagt ggcctcattg gggccagcgg     1260

ggccaccatg cccaccgaca caagcaaaag tgagaagctg gcttccagag cagtggcgcc     1320

acccacccct gccagcaaga gggactgtgt caagggcagt gctaccccca gtgggcagga     1380

gagccgcaca gcccccggag aagcccgcaa ggcggccaca ctgccagaga tgagcgcagg     1440

tgaggagagt agcagctcgg actccgaccc cgactccgcc tcgccgccca gcactggaca     1500

gaacccgtca gtgtccgttc agaccagcca ggactggaag cccacccgca gcctcatcga     1560

gcacgtattt gtcaccgacg tcactgccaa cctcatcacc gtcacagtga aggagtctcc     1620

caccagcgtg ggcttcttca acctgaggca ttactgaagc cccggcgcca ccagctgcgc     1680

ggtcttactc cccttccctg cctatggtgt cgcttggcta agtgactccc agcccaagcc     1740

ccctcaagag tctgggtcgg gggaggagga gtgggtggcc tccttgatgg gcaggcttgg     1800

aagggacttc tcccgcaccc cactctgtcc caggacatag ggcagggggc ctcactgcct     1860

tgttggtctc caccttgttc ctacctctgc aggcctcttt gctctcccct cttgcctcag     1920

gaaacccggt ggcacctgtg gctccaggtg actgtcttga acagagcggg cttcttcatg     1980

gctgcgttgt tgctgagttt gaactgctcc tccctggcct gcgtgactga atcacagctt     2040

tggtccctgt cttgcagggg ctgaggtgtc aggaggggac ttctggccca ccttgccttc     2100

agccctggag tgggcagaga gtattgtggg gaggcatggc cagtgggact agtgttccct     2160

ccatctggcc acagcttttg ggagatgggg tgggcagggg tggtcctggc tggcattgcc     2220

tgagccggca gtgatgaagt ggggagcttg cccttgacag gtgggggctg gctggggcct     2280

taatgtgaaa agacagtggc aggcagctgg agtagagcga gcccagcagc cctaaaaggc     2340

tgccttcatg gccatctagc cccagttcag ggcagcatcc atagcccaca agccagcgtg     2400

ggtggggcgg gggtggtccc acagctgggt tccacctgaa gagcctccgt gcctcggagc     2460

aggagaggca ggctatggct gccaccctcc ctcctgcctg tgtcccagtg agaactgacc     2520

tgagtcccct tccaaaccca gacccacctc ctgccccagg cccactgaag catgttccat     2580

ttctaaaaag cccagagttc agtgtgtccc aaggaaaacc caaagtggag gtgctcaggt     2640

ccaggggagt ccagtgggca ggacccttgg caggcaagcc cctcccttca ctcccaggac     2700

ctaccttctg ctagtaaagg actggcttca ttctaattat ggcccacaga ctgccccgga     2760

gacctggagg acagcagtgc tggcacttgg gtgtccatgg gcccgtctgc cggctctgcc     2820

tgtgctgcaa gtgttggccg tgggtccagc caacaactcc ctacgtcctg tgtggggccc     2880

tgcccaagtg gatgaggcat tccttgagga gtatcatttt ccctgacaat ccccatcacc     2940

tttaggggtt ccctgcttgg ctcctttcca gctgaaaaac tagacctgtg ccattgggga     3000

agctggacaa agtctagggg gcccgcctgg tagagggtcc cgggaagctg gatctgtcag     3060

cctcggccct gaggcccctg ttaactcaag actgtgagct gcctctaggt ggtcacgtct     3120

gggagctagc ttgtatggct tctgaccagt atcaggattt ctgttctgag agcagcgtgg     3180

gcagcaaggc agggcagccc agaggtggca gcggcaggca atctggtcac taggtctttg     3240

tgatgccaaa aataaaagag ggtggggtgg gtgctttctg ttcctctgat tggatggagt     3300

ccgccagcag gcatggggct acattccagt gcctgactat agggaggcac tcctgattcc     3360

atggagcagc ccggactttg agaatgggct ctggtttgcg gggggcaggc gtaccagact     3420

gcaagacccc ccagtacctc accgtgccaa ataggaagag gtggccttgg tgtagccaaa     3480

tggatctttt taacagtgtg cctttgggga gggacccatg tccatggctt cgttgagggc     3540

catccatatg ccagctgggg gccagcccac agtggccata ttggctgcag caggaatggt     3600

gcccacctcg gcgaattgaa gggctaagag tcccagatag ctaggccaga gctggaagca     3660

gacagtaagg ggaagagctg ctcccacagg agagggagag attccagctc actgcgcagc     3720

ctgggaggag gcgtggatcc tggcacgctg agcctcaggc accagcctcc ctgtgctcga     3780

cagcaaagtc ttgactcctt cctgctgagc actgtgctac cttcactgct ccaaagccag     3840

actaacagct ctccaagccc ttggggtgac tcggcttcca ggagctgttg gagaaatgag     3900

gatgtctgtc cctgtctgcc tgggcaggcc agattcctcc ccagcagccg ggtctctcca     3960

gaccctgatt cggtgccttt ctgtttacca gctacttcaa tcccaaagtt tgaatctgca     4020

gataccttac tcccagccac tttgccttct tactgtgttg tgtgtttttc ctggtgcttc     4080

aagagcgtgt gcagggcaag tgccgtcact gggaactgca ccagatgctc agacttggtt     4140

gtcttatgtt taccaataaa taaaagtaga ctttttctat ttttatttgc tgctatttgt     4200

gtgtgtgttt gtgtttgtgt agctaggtat ctggcacttc tgacgatgca ttgttgcttt     4260

tttcc                                                                 4265


<210>  1876
<211>  6813
<212>  DNA
<213>  homo sapiens

<400>  1876
ctccgccgca aactttttcc tccccatcct gtcgcggctc gaaaggaatg gaaaatggcg       60

gcctagacgc ggagtttcct gcccgacccg cggcggctcc ggcggcgcca tgacgcgctg      120

ggtgcccacc aagcgcgagg agaagtacgg cgtggctttt tataactatg atgccagagg      180

agcggatgaa ctttctttac agatcggaga cactgtgcac atcttagaaa catatgaagg      240

gtggtaccga ggttacacgt tacgaaaaaa gtctaagaag ggtatatttc ctgcttcata      300

tattcatctt aaagaagcga tagttgaagg aaaagggcaa catgaaacag tcatcccggg      360

tgacctcccc ctcatccagg aagtcaccac gacactccga gagtggtcca ccatctggag      420

gcagctctac gtgcaagata acagggagat gtttcgaagt gtgcggcaca tgatctatga      480

ccttattgaa tggcgatcac aaattctttc tggaactctg cctcaggatg aactcaaaga      540

actgaagaag aaggtcacag ccaaaattga ttatggaaac agaattctag atttggacct      600

ggtggttaga gatgaagatg ggaatatttt ggatccagaa ttaactagca cgattagtct      660

cttcagagct catgaaatag cttctaaaca agtggaggaa aggttacaag aggaaaaatc      720

tcaaaagcag aacatagata ttaacagaca agccaagttt gctgcaaccc cttctctggc      780

cttgtttgtg aacctcaaaa atgtggtttg taaaatagga gaagatgctg aagtcctcat      840

gtctctatat gaccctgtgg agtccaaatt catcagtgag aactacctgg ttcgctggtc      900

cagttcagga ttacctaaag acatagacag attacataat ttgcgagccg tgtttactga      960

cctcggaagc aaagacctga aaagggagaa aatcagtttt gtctgtcaga ttgttcgcgt     1020

gggtcgcatg gagctgaggg acaacaacac caggaaactg acctcggggt tgcggcgacc     1080

ttttggagtg gctgtgatgg atgtaacaga tataataaat ggaaaagtag atgatgaaga     1140

taagcagcat ttcattccct ttcagccggt ggcaggggag aatgacttcc ttcagactgt     1200

tataaacaaa gtcatcgctg ccaaagaagt caaccacaag gggcagggtt tgtgggtaac     1260

attgaaatta cttcctggag atatccatca gatccgaaaa gagtttccgc atttagtgga     1320

caggaccaca gctgtggctc gaaaaacagg gtttccggag ataatcatgc ctggtgatgt     1380

tcgaaatgat atctatgtaa cattagttca aggagatttt gataaaggaa gcaaaacaac     1440

agcgaagaac gtggaggtca cggtgtctgt gtacgatgag gatgggaaac gattagagca     1500

tgtgattttc ccgggtgctg gtgatgaagc gatttcagag tacaaatctg tgatttacta     1560

ccaagtaaag cagccacgct ggtttgagac tgttaaggtg gccattccca tcgaggacgt     1620

taaccgcagt caccttcggt ttaccttccg ccacaggtca tcacaggact ctaaggataa     1680

atctgagaaa atatttgcac tagcatttgt caagctgatg agatacgatg gtaccaccct     1740

gcgagacgga gagcacgatc ttatcgtcta taaggccgaa gcaaagaagc tggaagatgc     1800

tgccacgtac ttgagtctgc cctccacgaa ggcagagttg gaagaaaagg gccactcggc     1860

caccggcaag agcatgcaga gccttgggag ctgcaccatt agcaaggact ccttccagat     1920

ctccacgctc gtgtgctcca ccaaactgac tcagaacgtg gaccttctgg ggctcttgaa     1980

atggcgctcc aacaccagcc tgctgcagca gaacttgagg cagctgatga aagtcgatgg     2040

tggtgaagta gtgaagtttc ttcaggacac gttggatgcc ctcttcaaca tcatgatgga     2100

gaactcagag agtgagactt ttgacacgtt agtctttgat gctctggtat ttatcattgg     2160

actgattgct gatagaaaat ttcagcattt taatcctgtt ttggaaactt acattaagaa     2220

acactttagt gcaacgttag cctacacgaa gttgacaaaa gtgttgaaga actacgtgga     2280

cggtgctgag aagccgggag taaatgagca gctgtacaaa gccatgaaag cgctagaatc     2340

catcttcaag ttcatcgtgc gctccaggat cctgttcaat caactgtatg aaaacaaggg     2400

agaggctgac ttcgtggaat ctttgctgca gctcttcagg tccatcaatg acatgatgag     2460

cagcatgtca gaccagaccg tccgggtgaa gggggcagca ctgaaatact taccaacgat     2520

cgtcaacgat gtgaaattgg tgtttgatcc caaagagctc agcaaaatgt ttactgaatt     2580

catcctcaat gttcccatgg gcttgctgac catccagaaa ctctactgct tgatcgaaat     2640

cgtccacagt gacctcttca cacagcatga ctgcagagag atcctgcttc ccatgatgac     2700

cgatcagctc aagtaccatc tggagagaca ggaggacctg gaggcctgct gtcagctgct     2760

cagccacatc ctggaggtgc tgtacaggaa ggacgtgggg ccaacccaga ggcacgtcca     2820

gattatcatg gagaaacttc tccggaccgt gaaccgaacc gtcatttcca tgggacgaga     2880

ttctgaactc attggaaact tcgtggcttg catgacagct attttacgac aaatggaaga     2940

ttaccattat gcccacttga tcaagacttt tgggaaaatg aggactgatg tggtagattt     3000

cctaatggaa acattcatca tgtttaagaa cctcattgga aagaacgttt accccttcga     3060

ctgggtgatc atgaacatgg tgcaaaataa agtcttcctg cgagcaatta atcagtatgc     3120

agatatgctg aacaaaaaat ttctggatca agccaacttt gagctacagc tgtggaacaa     3180

ctactttcac ctggctgttg ctttccttac tcaagagtcc ctgcaactgg agaatttttc     3240

aagtgccaag agagccaaaa tccttaacaa gtacggagat atgaggagac agattggctt     3300

tgaaatcaga gacatgtggt acaaccttgg tcaacacaag ataaagttca ttccagaaat     3360

ggtgggccca atattagaaa tgacattaat tcccgagacg gagctgcgca aagccaccat     3420

ccccatcttc tttgatatga tgcagtgtga attccattcg acccgaagct tccaaatgtt     3480

tgaaaatgag atcatcacca agctggatca tgaagtcgaa ggaggcagag gagacgaaca     3540

gtacaaagtg ttatttgata aaatccttct ggaacactgc aggaagcaca aatacctcgc     3600

caaaacagga gaaacttttg taaaactcgt tgtgcgctta atggaaaggc ttttggatta     3660

tagaaccatc atgcacgacg agaacaaaga aaaccgcatg agctgcaccg tcaatgtgct     3720

gaatttctac aaagaaattg aaagagaaga aatgtatata aggtatttgt acaagctctg     3780

tgacctgcac aaggagtgtg ataactacac cgaagcggct tacaccttgc ttctccatgc     3840

aaagcttctt aagtggtcgg aggatgtgtg tgtggcccac ctcacccagc gggacgggta     3900

ccaggccacc acgcagggac agctgaagga gcagctctac caggaaatca tccactactt     3960

cgacaaaggc aagatgtggg aggaggccat tgccttgggc aaggagctag ccgagcagta     4020

tgagaacgaa atgtttgatt atgagcaact cagcgaattg ctgaaaaaac aggctcagtt     4080

ttatgaaaac atcgtcaaag tgatcaggcc caagcctgac tattttgctg ttggctacta     4140

cggacaaggg ttccccacat tcctgcgggg aaaagttttc atttaccgag ggaaagagta     4200

tgagcgccgg gaagattttg aggctcggct cttaactcag tttccaaacg ccgagaaaat     4260

gaagacaaca tctccaccag gcgacgatat taaaaactct cctggccagt atattcagtg     4320

cttcacagtg aagcccaaac tcgatctgcc tcctaagttt cacaggccag tgtcagagca     4380

gattgtaagt ttttacaggg tgaacgaggt ccagcgattt gaatattctc ggccaatccg     4440

gaagggagag aaaaacccag acaatgaatt tgcgaatatg tggatcgaga gaaccatata     4500

tacaactgca tataaattac ctggaatttt aaggtggttt gaggtcaagt ctgttttcat     4560

ggtggaaatc agccccctgg agaatgccat tgagaccatg cagctgacga acgacaagat     4620

caacagcatg gtgcagcagc acctggatga ccccagcctg cccatcaacc cgctctccat     4680

gctcctgaac ggcatcgtgg acccagctgt catggggggc ttcgcaaact acgaaaaggc     4740

cttctttaca gaccggtacc tgcaggagca ccctgaggcc catgaaaaga tcgagaagct     4800

caaggacctg attgcttggc agattccttt tctggccgaa gggatcagaa tccatggaga     4860

caaagtcacg gaggcactga ggccgttcca cgagaggatg gaggcctgtt tcaaacagct     4920

gaaggaaaag gtggagaaag agtacggcgt ccgaatcatg ccctcaagtc tggatgatag     4980

aagaggcagc cgcccccggt ccatggtgcg gtccttcacg atgccttcct catcccgccc     5040

tctgtctgtg gcctctgtct cttccctctc atcggacagc accccttcca gaccaggctc     5100

cgacgggttt gccctggagc ctctcctgcc aaagaaaatg cactccaggt cccaggacaa     5160

gctggacaag gatgacctgg agaaggagaa gaaggacaag aagaaggaaa aaaggaacag     5220

caaacatcaa gagatatttg agaaagaatt taaacccacc gacatttccc tgcagcagtc     5280

tgaggctgtg atcctttcgg aaacgataag tcccctgcgg ccccagagac cgaagagcca     5340

ggtgatgaac gtcattggaa gcgaaaggcg cttctcggtg tccccctcgt caccgtcctc     5400

ccagcaaaca ccccctccag ttacaccaag ggccaagctc agcttcagca tgcagtcgag     5460

cttggagctg aacggcatga cgggggcgga cgtggccgat gtcccacccc ctctgcctct     5520

caaaggcagc gtggcagatt acgggaattt gatggaaaac caggacttgc tgggctcgcc     5580

aacacctcca cctccccctc cacaccagag gcatctgcca cctccactgc ccagcaaaac     5640

tccgcctcct ccccctccaa agacaactcg caagcagaca tcggtggact ccgggatcgt     5700

gcagtgacgt cgcaaggctc tctggaaaga gtgtgctgcc cctccccatc tccatgccct     5760

ctccttctgt gtcccctgag tctgctgttt acctcattgg gcctgtgatg ttaacatttc     5820

gtgcgactgc tttttcttca aaggagttca gttctcacca tggagtgagt ggcctttagc     5880

gtcatggagc aaggtgggtc tgggaggtag atatgggtcc gggatgtgct atcgtagtta     5940

tcagagttgg gggcctctga gtgtgtctgg ctctgagaga gtctgagtct tgcccaaaca     6000

ttctttcttt ttgtgccaaa tgacttgcat ttgcaaagag ctcaattgct ctgagctcag     6060

ccaagtagga gaggctaggc catcactctt aggaagctgt gtagtgatga tgtataagaa     6120

tcctcctcac tgtcatggga tgttgtatcc agcccctcct tgttccagcc ggtggtgtga     6180

cttcgttggt tgaggtgtgt ctccaaccta catcagacca tgaagttcaa cccctccagg     6240

gaagctcctg atttcccctg cataattgaa aataggatat ttctcagcta ttgaacagtt     6300

actaatttat ggggtggaaa cagcattaag aatactgaat caaatggaaa aacaaatgaa     6360

tacaggaaga taagtgttcg ttcttttctg aaaaagagta tgtgtaccac aagagctggt     6420

tttaattggg tgaattgttt ttgtcctcat tctgtacaga aatttgtata tatgatggtt     6480

cttagaactt gttttaattt ttgtggtcct tccgtttatt ataataggcg tccaccaatg     6540

attatccata tgtgttctta atttttaact gctggaagtg ttaaaacaca cacacacaca     6600

cacacacatt ttttttttga gaactccaaa gtcctgaaaa ttttggtgga caatgatttt     6660

taaaaaacta actttgtata acctaatatt tgtattctct catctatatt tttttattca     6720

ctataatcat gatactcttc taatagactt aaaagttaat cattgacaac gaaaaataaa     6780

atgttatttt aaaagacaaa aaaaaaaaaa aaa                                  6813


<210>  1877
<211>  4835
<212>  DNA
<213>  homo sapiens

<400>  1877
ccttgccaag taacagcttt gctgtccaac atcgtgtgct gcttcgcgag aaagtcacat       60

tcggaccctt tggctagatt atcttagacg aattttacaa tgtgaagttc tgcatagatg      120

ccagtcaacc agatgttgga agctggctca agtacattag attcgctggc tgttatgatc      180

agcacaacct tgttgcatgc cagataaatg atcagatatt ctatagagta gttgcagaca      240

ttgcgccggg agaggagctt ctgctgttca tgaagagcga agactatccc catgaaacta      300

tggcgccgga tatccacgaa gaacggcaat atcgctgcga agactgtgac cagctctttg      360

aatctaaggc tgaactagca gatcaccaaa agtttccatg cagtactcct cactcagcat      420

tttcaatggt tgaagaggac tttcagcaaa aactcgaaag cgagaatgat ctccaagaga      480

tacacacgat ccaggagtgt aaggaatgtg accaagtttt tcctgatttg caaagcctgg      540

agaaacacat gctgtcacat actgaagaga gggaatacaa gtgtgatcag tgtcccaagg      600

catttaactg gaagtccaat ttaattcgcc accagatgtc acatgacagt ggaaagcact      660

atgaatgtga aaactgtgcc aaggttttca cggaccctag caaccttcag cggcacattc      720

gctctcagca tgtcggtgcc cgggcccatg catgcccgga gtgtggcaaa acgtttgcca      780

cttcgtcggg cctcaaacaa cacaagcaca tccacagcag tgtgaagccc tttatctgtg      840

aggtctgcca taaatcctat actcagtttt caaacctttg ccgtcataag cgcatgcatg      900

ctgattgcag aacccaaatc aagtgcaaag actgtggaca aatgttcagc actacgtctt      960

ccttaaataa acacaggagg ttttgtgagg gcaagaacca ttttgcggca ggtggatttt     1020

ttggccaagg catttcactt cctggaaccc cagctatgga taaaacgtcc atggttaata     1080

tgagtcatgc caacccgggc cttgctgact attttggcgc caataggcat cctgctggtc     1140

ttacctttcc aacagctcct ggattttctt ttagcttccc tggtctgttt ccttccggct     1200

tgtaccacag gcctcctttg atacctgcta gttctcctgt taaaggacta tcaagtactg     1260

aacagacaaa caaaagtcaa agtcccctca tgacacatcc tcagatactg ccagctacac     1320

aggatatttt gaaggcacta tctaaacacc catctgtagg ggacaataag ccagtggagc     1380

tccagcccga gaggtcctct gaagagaggc cctttgagaa aatcagtgac cagtcagaga     1440

gtagtgacct tgatgatgtc agtacaccaa gtggcagtga cctggaaaca acctcgggct     1500

ctgatctgga aagtgacatt gaaagtgata aagagaaatt taaagaaaat ggtaaaatgt     1560

tcaaagacaa agtaagccct cttcagaatc tggcttcaat aaataataag aaagaataca     1620

gcaatcattc cattttctca ccatctttag aggagcagac tgcggtgtca ggagctgtga     1680

atgattctat aaaggctatt gcttctattg ctgaaaaata ctttggttca acaggactgg     1740

tggggctgca agacaaaaaa gttggagctt taccttaccc ttccatgttt cccctcccat     1800

tttttccagc attctctcaa tcaatgtacc catttcctga tagagacttg agatcgttac     1860

ctttgaaaat ggaaccccaa tcaccaggtg aagtaaagaa actgcagaag ggcagctctg     1920

agtccccctt tgatctcacc actaagcgaa aggatgagaa gcccttgact ccagtcccct     1980

ccaagcctcc agtgacacct gccacaagcc aagaccagcc cctggatcta agtatgggca     2040

gtaggagtag agccagtggg acaaagctga ctgagcctcg aaaaaaccac gtgtttgggg     2100

gaaaaaaagg aagcaacgtc gaatcaagac ctgcttcaga tggttccttg cagcatgcaa     2160

gacccactcc tttctttatg gaccctattt acagagtaga gaaaagaaaa ctaactgacc     2220

cacttgaagc tttaaaagag aaatacttga ggccttctcc aggattcttg tttcacccac     2280

aattccaact gcctgatcag agaacttgga tgtcagctat tgaaaacatg gcagaaaagc     2340

tagagagctt cagtgccctg aaacctgagg ccagtgagct cttacagtca gtgccctcta     2400

tgttcaactt cagggcgcct cccaatgccc tgccagagaa ccttctgcgg aagggaaagg     2460

agcgctatac ctgcagatac tgtggcaaga tttttccaag gtctgcaaac ctaacacggc     2520

acttgagaac ccacacagga gagcagcctt acagatgcaa atactgtgac agatcattta     2580

gcatatcttc taacttgcaa aggcatgttc gcaacatcca caataaagag aagccattta     2640

agtgtcactt atgtgatagg tgttttggtc aacaaaccaa tttagacaga cacctaaaga     2700

aacatgagaa tgggaacatg tccggtacag caacatcgtc gcctcattct gaactggaaa     2760

gtacaggtgc gattctggat gacaaagaag atgcttactt cacagaaatt cgaaatttca     2820

ttgggaacag caaccatggc agccaatctc ccaggaatgt ggaggagaga atgaatggca     2880

gtcattttaa agatgaaaag gctttggtga ccagtcaaaa ttcagacttg ctggatgatg     2940

aagaagttga agatgaggtg ttgttagatg aggaggatga agacaatgat attactggaa     3000

aaacaggaaa ggaaccagtg acaagtaatt tacatgaagg aaaccctgag gatgactatg     3060

aagaaaccag tgccctggag atgagttgca agacatcccc agtgaggtat aaagaggaag     3120

aatataaaag tggactttct gctctagatc atataaggca cttcacagat agcctcaaaa     3180

tgaggaaaat ggaagataat caatattctg aagctgagct gtcttctttt agtacttccc     3240

atgtgccaga ggaacttaag cagccgttac acagaaagtc caaatcgcag gcatatgcta     3300

tgatgctgtc actgtctgac aaggagtccc tccattctac atcccacagt tcttccaacg     3360

tgtggcacag tatggccagg gctgcggcgg aatccagtgc tatccagtcc ataagccacg     3420

tatgacgtta tcaaggttga ccagagtggg accaagtcca acagtagcat ggctctttca     3480

tataggacta tttacaagac tgctgagcag aatgccttat aaacctgcag ggtcactcat     3540

ctaaagtcta gtgaccttaa actgaatgat ttaaaaaaga aaagaaagaa aaaagaaact     3600

atttattctc gatattttgt tttgcacagc aaaggcagct gctgacttct ggaagatcaa     3660

tcaatgcgac ttaaagtgat tcagtgaaaa caaaaaactt ggtgggctga aggcatcttc     3720

cagtttaccc caccttaggg tatgggtggg tgagaagggc agttgagatg gcagcattga     3780

tatgaatgaa cactccatag aaactgaatt ctcttttgta caagatcacc tgacatgatt     3840

gggaacagtt gcttttaatt acagatttaa tttttttctt cgttaaagtt ttatgtaatt     3900

taaccctttg aagacagaag tagttggatg aaatgcacag tcaattatta tagaaactga     3960

taacagggag tacttgttcc cccttttgcc ttcttaagta cattgtttaa aactagggaa     4020

aaagggtatg tgtatattgt aaactatgga tgttaacact caaagaggtt aagtcagtga     4080

agtaacctat tcatcaccag taccgctgta ccactaataa attgtttgcc aaatccttgt     4140

aataacatct taattttaga caatcatgtc actgttttta atgtttattt ttttgtgtgt     4200

gttgcgtgta tcatgtattt atttgttggc aaactattgt ttgttgatta aaatagcact     4260

gttccagtca gccactactt tatgacgtct gaggcacacc cctttccgaa tttcaaggac     4320

caaggtgacc cgacctgtgt atgagagtgc caaatggtgt ttggcttttc ttaacattcc     4380

tttttgtttg tttgttttgt tttccttctt aatgaactaa atacgaatag atgcaactta     4440

gtttttgtaa tactgaaatc gattcaattg tataaacgat tataatttct ttcatggaag     4500

catgattctt ctgattaaaa actgtactcc atattttatg ctggttgtct gcaagcttgt     4560

gcgatgttat gttcatgtta atcctatttg taaaatgaag tgttcccaac cttatgttaa     4620

aagagagaag taaataacag actgtattca gttattttgc cctttattga ggaaccagat     4680

ttgttttctt tttgtttgta atctcatttt gaaataatca gcaagttgag gtactttctt     4740

caaatgcttt gtacaatata aactgttatg cctttcagtg cattactatg ggaggagcaa     4800

ctaaaaaata aagacttaca aaaaggagta ttttt                                4835


<210>  1878
<211>  657
<212>  DNA
<213>  homo sapiens

<400>  1878
gacaactcgg tggtggccac tgcgcagacc agacttcgct cgtactcgtg cgcctcgctt       60

cgcttttcct ccgcaaccat gtctgacaaa cccgatatgg ctgagatcga gaaattcgat      120

aagtcgaaac tgaagaagac agagacgcaa gagaaaaatc cactgccttc caaagaaacg      180

attgaacagg agaagcaagc aggcgaatcg taatgaggcg tgcgccgcca atatgcactg      240

tacattccac aagcattgcc ttcttatttt acttctttta gctgtttaac tttgtaagat      300

gcaaagaggt tggatcaagt ttaaatgact gtgctgcccc tttcacatca aagaactact      360

gacaacgaag gccgcgcctg cctttcccat ctgtctatct atctggctgg cagggaagga      420

aagaacttgc atgttggtga aggaagaagt ggggtggaag aagtggggtg ggacgacagt      480

gaaatctaga gtaaaaccaa gctggcccaa ggtgtcctgc aggctgtaat gcagtttaat      540

cagagtgcca tttttttttt tgttcaaatg attttaatta ttggaatgca caattttttt      600

aatatgcaaa taaaaagttt aaaaacttaa aaaaaaaaaa aaaaaaaaaa aaaaaaa         657


<210>  1879
<211>  4459
<212>  DNA
<213>  homo sapiens

<400>  1879
cctagacaaa ggggccggcg cggcggagca gactggtgca gcctgggccg cgcgctcaga       60

gcgctgggcg tctgggcagc tgagtgggca gagctgaccc ggtgcgggtg ggagtcaggg      120

cgcccggaaa acccggctct gggtagcaga ccccgcccgg gctggctcgg cgccgggcct      180

tcgggcttcc actcagtctt tgaccctcgg tcctcgctca gcggcccggc aggccgcaca      240

actgtaaccg ctgccccggc cgccgcccgc tccttctcgg tccggcgggc acagagcgca      300

gcgcggcggg gccggcggca tggctgtgtc ctggaggagc tggctcgcca acgaaggggt      360

taaacacctc tgcctgttca tctggctctc catgaatgtc ctgcttttct ggaaaacctt      420

cttgctgtat aaccaagggc cagagtatca ctacctccac cagatgttgg ggctaggatt      480

gtgtctaagc agagcctcag catctgttct taacctcaac tgcagcctta tccttttacc      540

catgtgccga acactcttgg cttacctccg aggatcacag aaggttccaa gcaggagaac      600

caggagattg ttggataaaa gcagaacatt ccatattacc tgtggtgtta ctatctgtat      660

tttctcaggc gtgcatgtgg ctgcccatct ggtgaatgcc ctcaacttct cagtgaatta      720

cagtgaagac tttgttgaac tgaatgcagc aagataccga gatgaggatc ctagaaaact      780

tctcttcaca actgttcctg gcctgacagg ggtctgcatg gtggtggtgc tattcctcat      840

gatcacagcc tctacatatg caataagagt ttctaactat gatatcttct ggtatactca      900

taacctcttc tttgtcttct acatgctgct gacgttgcat gtttcaggag ggctgctgaa      960

gtatcaaact aatttagata cccaccctcc cggctgcatc agtcttaacc gaaccagctc     1020

tcagaatatt tccttaccag agtatttctc agaacatttt catgaacctt tccctgaagg     1080

attttcaaaa ccggcagagt ttacccagca caaatttgtg aagatttgta tggaagagcc     1140

cagattccaa gctaattttc cacagacttg gctttggatt tctggacctt tgtgcctgta     1200

ctgtgccgaa agactttaca ggtatatccg gagcaataag ccagtcacca tcatttcggt     1260

cataagtcat ccctcagatg tcatggaaat ccgaatggtc aaagaaaatt ttaaagcaag     1320

acctggtcag tatattactc tacattgtcc cagtgtatct gcattagaaa atcatccatt     1380

taccctcaca atgtgtccaa ctgaaaccaa agcaacattt ggggttcatc ttaaaatagt     1440

aggagactgg acagaacgat ttcgagattt actactgcct ccatctagtc aagactccga     1500

aattctgccc ttcattcaat ctagaaatta tcccaagctg tatattgatg gtccttttgg     1560

aagtccattt gaggaatcac tgaactatga ggtcagcctc tgcgtggctg gaggcattgg     1620

agtaactcca tttgcatcaa tactcaacac cctgttggat gactggaaac catacaagct     1680

tagaagacta tactttattt gggtatgcag agatatccag tccttccgtt ggtttgcaga     1740

tttactctgt atgttgcata acaagttttg gcaagagaac agacctgact atgtcaacat     1800

ccagctgtac ctcagtcaaa cagatgggat acagaagata attggagaaa aatatcatgc     1860

actgaattca agactgttta taggacgtcc tcggtggaaa cttttgtttg atgaaatagc     1920

aaaatataac agaggaaaaa cagttggtgt tttctgttgt ggacccaatt cactatccaa     1980

gactcttcat aaactgagta accagaacaa ctcatatggg acaagatttg aatacaataa     2040

agagtctttc agctgaaaac ttttgccatg aagcaggact ctaaagaagg aatgagtgca     2100

atttctaaga ctttgaaact cagcggaatc aatcagctgt gttatgccaa agaatagtaa     2160

ggttttctta tttatgatta tttaaaatgg aaatgtgaga atgtggcaag atgaccgtca     2220

cattacatgt ttaatctgga aaccaaagag accctgaaga atatttgatg tgatgattca     2280

cttttcagtt ctcaaattaa aagaaaactg ttagatgcac actgttgatt ttcatggtgg     2340

attcaagaac tccctagtga ggagctgaac ttgctcaatc taaggctgat tgtcgtgttc     2400

ctctttaaat tgtttttggt tgaacaaatg caagattgaa caaaattaaa aattcattga     2460

agctgaaatt ccattttctg tgttgtgtat aaacagagta gctttaattt gcaagcactc     2520

caggcaaata tattagatgt ttgaaaacac agcacaagac tctgtattga tacgggtact     2580

ttgtgtcaat atctaatcgt ctccactact tatgctaata cctctatttg atatctgaag     2640

actatatgct aactgaacct tcctcaaatg ttgttatagt atctattttt atatattttt     2700

ttctttttat tcctctctct agggaaatat gccttccctt agcatgcatt agacataatg     2760

atttaatagg tccctttcat cttcatttaa atctatcact attgcatggt aatgaaaata     2820

ttcctactat aaattataaa gggatatata tatatggata tatatatgta tatacacata     2880

tatatataca cacacacaca catatatata tatatatata tatatacaca tatactaata     2940

acttttccct tttttcagca tttttgtctc tattattatt attgtttttt tcccaggtag     3000

ggtttgtctt aggctgtagc ctctaaggat agttagttaa tttgcacttt gagaccaaag     3060

gacatcatgt gtgtcagtag ggactgaata taagatttat ctcctttgcc acacattggt     3120

ttatgatgga gacattgaaa gtctagtcat attcctgaac agtaaaacct gtattttacc     3180

ttttaagtaa gaggaaatat gatattctta ttcaaactta agtttagaat ccagaatatt     3240

actgtcgcac tttttggtat cctgagtttc catagggaac tattgggttt aaagtcaccg     3300

ttggaactac actgtgtgat cttataaact tatgttccct ggctatcata ttcttggctc     3360

agaacaatat ttcccattac tatcttaaga attaaggcat tcatggctca cgcctgtaat     3420

cccggcactt tgggaggcca aggcaggtgg atcacgaggt cagagttcaa gaccagcctg     3480

accaagttgg tgaaacccca tcgctactaa aaatacaaat attaggcggg tgtggtggcg     3540

ggtgcctata atcccaacta ctcgggagac tgaggcaaag aatcgcttga acccggtggg     3600

cggaggttgc agtgagccaa gattgcacca ctgcactcca gcctgggtga cagagcaaga     3660

ttccatctca aaaaaaaaaa aaaaaaaaaa aaaaaagaat taaagcattc atacagttta     3720

gtgattttgt ttagtagtcg gctatcaatt gctatcaaat ataacactgc tgaaatcagc     3780

agtgtgactt accttgccat tgttaaaatg ttacataaaa cataacatga tagatgctaa     3840

ggcctttttt tgctataatt caccaatagc aatcaagcat gctaacccat actgaatgat     3900

atttacttgt agatatttct tcctttcctt gaaattctcc tttctatgga aagaagatga     3960

acccaaaaaa gtgataggaa atgtggaatg ctcatgcaga tttagctctg aaggcatatt     4020

taataactag tatgtcttga caacagtctt tagattaaaa agaattttca tggaaacatt     4080

taacagaaag aactagtaaa aagacacttt gagttagtcc aggcttaatg tgcaatactg     4140

actctatact gatcataatt tatttatgcg atcatattaa tagacctaat ttcattaaaa     4200

caggtagaag atttttcaaa agaaagatga tgtttcaaag ctggtctgcc attctagatg     4260

agcctccttg cttatttaag ttccagtagg tgttcaaatg ttaaatgtta aacataggtc     4320

atctttgctt ctgcagggct tcatcttgca tgtttaagag aactttgttt tattttgagg     4380

gattatttct ctggggatca ttcttataat acaagcctta aatcactaat tttagtagca     4440

ataaatgtta aaattgaaa                                                  4459


<210>  1880
<211>  1720
<212>  DNA
<213>  homo sapiens

<400>  1880
actgcagggt gcgaaggggc cggcgccgct gccgagttac gagtcggcga aagcggcggg       60

aagttcgtac tgggcagaac gcgacgggtc tgcggcttag gtgaaaatgc ctcgtgtaaa      120

agcagctcaa gctggaagac agagctctgc aaagagacat cttgcagaac aatttgcagt      180

tggagagata ataactgaca tggcaaaaaa ggaatggaaa gtaggattac ccattggcca      240

aggaggcttt ggctgtatat atcttgctga tatgaattct tcagagtcag ttggcagtga      300

tgcaccttgt gttgtaaaag tggaacccag tgacaatgga cctcttttta ctgaattaaa      360

gttctaccaa cgagctgcaa aaccagagca aattcagaaa tggattcgta cccgtaagct      420

gaagtacctg ggtgttccta agtattgggg gtctggtcta catgacaaaa atggaaaaag      480

ttacaggttt atgataatgg atcgctttgg gagtgacctt cagaaaatat atgaagcaaa      540

tgccaaaagg ttttctcgga aaactgtctt gcagctaagc ttaagaattc tggatattct      600

ggaatatatt cacgagcatg agtatgtgca tggagatatc aaggcctcaa atcttcttct      660

gaactacaag aatcctgacc aggtgtactt ggtagattat ggccttgctt atcggtactg      720

cccagaagga gttcataaag aatacaaaga agaccccaaa agatgtcacg atggcactat      780

tgaattcacg agcatcgatg cacacaatgg cgtggcccca tcaagacgtg gtgatttgga      840

aatacttggt tattgcatga tccaatggct tactggccat cttccttggg aggataattt      900

gaaagatcct aaatatgtta gagattccaa aattagatac agagaaaata ttgcaagttt      960

gatggacaaa tgttttcctg agaaaaacaa accaggtgaa attgccaaat acatggaaac     1020

agtgaaatta ctagactaca ctgaaaaacc tctttatgaa aatttacgtg acattctttt     1080

gcaaggacta aaagctatag gaagtaagga tgatggcaaa ttggacctca gtgttgtgga     1140

gaatggaggt ttgaaagcaa aaacaataac aaagaagcga aagaaagaaa ttgaagaaag     1200

caaggaacct ggtgttgaag atacggaatg gtcaaacaca cagacagagg aggccataca     1260

gacccgttca agaaccagaa agagagtcca gaagtaattc agatgctgtg aaccagattt     1320

ccttttcttt gttttctttt gacttttttc tccttttcta tttgaactgt tttattttcc     1380

tgtgagtctt gcgaggtgga agtaatgatt aaatactcat gtgttcagaa aacataaact     1440

ttttttataa aaatattttg tacaattcat taaaggctaa tttatgaaat ttgaaaatct     1500

tcaggttata ctccttaagt tatcccaaag ccgtgtgttt gtgatgtttt ggagtacata     1560

tatatgaaaa ttattatgac acgcactttt ctaatcattg tacatttctc agagtggata     1620

aaaatgtttg acaaagtcct cacttttaag gaaatgcaaa gcttaaaata aaactctctt     1680

ttgtttgatg caaacacaca gtaaaaaaaa aaaaaaaaaa                           1720


<210>  1881
<211>  3312
<212>  DNA
<213>  homo sapiens

<400>  1881
cccgcccctg acgccgccgg taactgcgag agtcggggtc ggtgcggttt gataagtggt       60

cggttcctgg agctgcggtc ttctgctagc ctgatccgca gcttcagcct ccgccgcctc      120

ctcagccctc ggcgccgccg ctggcgccgc cgcctgaccc gcaggccgcc gcgggccgca      180

gagcccatga gggcgcgggc accgccgccg cctccgcggc gtcgccgtcg tcccggagcg      240

ccccgggctg gcgcgggcat ggccgcggca tgagcgtgga gccgccgccg gagctggagg      300

agaaggcggc gtcggagccc gaggcgggag ccatgccgga gaagcgcgcg ggcgcgcagg      360

ccgcggggag cacctggcta caaggctttg gccgaccaag tgtgtaccat gctgctattg      420

tcatcttcct tgaattcttt gcgtggggcc tgttgacaac tccaatgttg actgttctac      480

atgaaacatt ttctcaacac acattcctca tgaatggtct cattcaaggt gtaaagggcc      540

tgctctcttt tttgagtgcc ccactcattg gtgccctgtc tgatgtgtgg gggaggaagc      600

cctttctcct cggcactgta ttctttacct gcttcccaat cccactgatg aggatcagcc      660

catggtggta ttttgcgatg atttctgtgt ctggagtctt ctcggtcacg ttttctgtta      720

tatttgccta tgtagctgat gtcactcagg agcacgagcg aagtacagct tatggatggg      780

tctcagccac ctttgcggct agtcttgtca gcagcccggc cattggagca tatctttctg      840

ccagttacgg agacagcctc gttgtgctgg tggccacagt ggtggctctt ctggacatct      900

gcttcatctt agtggctgtt ccagaatctc tgcctgagaa aatgagaccg gtttcctggg      960

gagctcagat ttcttggaaa caagcagacc cttttgcgtc gttgaagaaa gttggaaaag     1020

attctactgt cttactaatc tgcatcaccg tgtttctttc ataccttcct gaagctggac     1080

agtattcaag tttttttctc tatctcaggc aggtcatagg ttttggatct gttaaaattg     1140

cagcattcat agctatggta ggaattctgt ctattgtggc tcagacggcc tttcttagca     1200

tcttgatgag atcattagga aataagaata ctgtcctcct tggcttgggc ttccagatgc     1260

tccagttagc ctggtacggt tttggatcac aggcctggat gatgtgggca gcagggaccg     1320

tggctgccat gtccagcatc acgtttccgg caatcagtgc cctcgtctct cggaatgcag     1380

agtcagatca gcaaggagtt gcccagggga tcataactgg aataagagga ctatgcaatg     1440

gcctggggcc agcactgtat ggcttcatat tctacatgtt ccatgtggaa ctgactgagt     1500

tgggcccgaa attgaattct aacaacgttc ccctgcaggg agctgtcatc ccaggcccgc     1560

cgtttttatt tggggcatgt atagtcctta tgtcttttct ggttgcctta ttcattcctg     1620

aatacagtaa agccagtgga gttcaaaaac acagtaacag cagcagcggc agcctgacca     1680

acaccccaga acggggcagt gatgaggaca ttgagccact actgcaagac agcagcatct     1740

gggagctctc ttcatttgag gagcctggga atcagtgcac tgagctgtaa actcggcaga     1800

aagtgggatt ctgcatacgc catctctgag agccatggag ggagccacac ccctggtgac     1860

ttcatggtgc tggatgggag acgctagcgg catccttcag ggccaagttt gataaatacc     1920

accgccatca ttctgctcat cctcctcctg tttttttttt ttctcttaca ttcttttttt     1980

ttttcctgtt tatacattag aacaagataa gatttgaaat acttccttgc aaataatgtg     2040

caactcccaa ggtgaaactc aaatagaaaa agtcatctct ctggtagaaa ggatggcttt     2100

cctgtaatga ctatagagta agagtggcag caatctttcc atgccctttt cagcagaagg     2160

cacagaacag tagcgggact gccatctctg gcaagatttc aggtaaagaa tctcttctta     2220

atttctacct tcctgtttct ctgaatcagc ccataggtgt tgatgagtgg ccactcttaa     2280

agagtcactc agtatcaggg atctactgtc tttgttcaaa ggtcaaataa aaacctagtc     2340

tccttttatt ctactttcta ttcttagcta gaatgaaact cagcatatat acacttctgg     2400

acataataat attgaatagt aattaccttt actagatgaa agaaattttc attacaaact     2460

taaatcatgt aaaactcaac aactcagatt cctggacctg gtgtcctggt tgggtccaag     2520

gtgattttac agaagaaaaa aacaactcaa gcattctggt ggcaacatag agattgtagg     2580

ctgcttctaa gaaagttatt aacaatttgg aaattcctaa gtaggatgag agttagtaac     2640

tggatacgag tgaagtttat atccaagttc agactcaaag gcattattat gatttgcttc     2700

ttcccatgtc ttccatgtcc tgcttctcaa agtttttctc atccatcaca ctcctgcctt     2760

aactgctctg agtatgcatt tgttttcaat tcatctttat ttcaatctgt ttaacttttg     2820

aatcgcatgg gaatacgcac attaagttcc tttctaaaat aaggttttat gaagctgagt     2880

ttcacgataa gtgtcttgct attttttgag atgttttatg gacaaagaaa actttacaga     2940

tttatatgta ttttgctgca ccagtaaatg gaccattaac tagggcccac ctttaacaga     3000

gcaccccttt gaaagtttta taggtatgaa atatatgtag atatttgtaa agggttttaa     3060

tttttttttt ttgatggggt gctgtgtaaa tcttgtattt ataaatgtaa tgaaggtatt     3120

gacagaaaaa aatatataca acttttataa aggattgtgt actgactgaa tacatttaaa     3180

agaaaatata ttttgaaacc tgttctgcta tgaacagaga taacatatct ttttactatg     3240

ctattggttt ttaggttaag cttcctaatg cataataaat ttacagtggt tacttttaaa     3300

aaaaaaaaaa aa                                                         3312


<210>  1882
<211>  3312
<212>  DNA
<213>  homo sapiens

<400>  1882
cccgcccctg acgccgccgg taactgcgag agtcggggtc ggtgcggttt gataagtggt       60

cggttcctgg agctgcggtc ttctgctagc ctgatccgca gcttcagcct ccgccgcctc      120

ctcagccctc ggcgccgccg ctggcgccgc cgcctgaccc gcaggccgcc gcgggccgca      180

gagcccatga gggcgcgggc accgccgccg cctccgcggc gtcgccgtcg tcccggagcg      240

ccccgggctg gcgcgggcat ggccgcggca tgagcgtgga gccgccgccg gagctggagg      300

agaaggcggc gtcggagccc gaggcgggag ccatgccgga gaagcgcgcg ggcgcgcagg      360

ccgcggggag cacctggcta caaggctttg gccgaccaag tgtgtaccat gctgctattg      420

tcatcttcct tgaattcttt gcgtggggcc tgttgacaac tccaatgttg actgttctac      480

atgaaacatt ttctcaacac acattcctca tgaatggtct cattcaaggt gtaaagggcc      540

tgctctcttt tttgagtgcc ccactcattg gtgccctgtc tgatgtgtgg gggaggaagc      600

cctttctcct cggcactgta ttctttacct gcttcccaat cccactgatg aggatcagcc      660

catggtggta ttttgcgatg atttctgtgt ctggagtctt ctcggtcacg ttttctgtta      720

tatttgccta tgtagctgat gtcactcagg agcacgagcg aagtacagct tatggatggg      780

tctcagccac ctttgcggct agtcttgtca gcagcccggc cattggagca tatctttctg      840

ccagttacgg agacagcctc gttgtgctgg tggccacagt ggtggctctt ctggacatct      900

gcttcatctt agtggctgtt ccagaatctc tgcctgagaa aatgagaccg gtttcctggg      960

gagctcagat ttcttggaaa caagcagacc cttttgcgtc gttgaagaaa gttggaaaag     1020

attctactgt cttactaatc tgcatcaccg tgtttctttc ataccttcct gaagctggac     1080

agtattcaag tttttttctc tatctcaggc aggtcatagg ttttggatct gttaaaattg     1140

cagcattcat agctatggta ggaattctgt ctattgtggc tcagacggcc tttcttagca     1200

tcttgatgag atcattagga aataagaata ctgtcctcct tggcttgggc ttccagatgc     1260

tccagttagc ctggtacggt tttggatcac aggcctggat gatgtgggca gcagggaccg     1320

tggctgccat gtccagcatc acgtttccgg caatcagtgc cctcgtctct cggaatgcag     1380

agtcagatca gcaaggagtt gcccagggga tcataactgg aataagagga ctatgcaatg     1440

gcctggggcc agcactgtat ggcttcatat tctacatgtt ccatgtggaa ctgactgagt     1500

tgggcccgaa attgaattct aacaacgttc ccctgcaggg agctgtcatc ccaggcccgc     1560

cgtttttatt tggggcatgt atagtcctta tgtcttttct ggttgcctta ttcattcctg     1620

aatacagtaa agccagtgga gttcaaaaac acagtaacag cagcagcggc agcctgacca     1680

acaccccaga acggggcagt gatgaggaca ttgagccact actgcaagac agcagcatct     1740

gggagctctc ttcatttgag gagcctggga atcagtgcac tgagctgtaa actcggcaga     1800

aagtgggatt ctgcatacgc catctctgag agccatggag ggagccacac ccctggtgac     1860

ttcatggtgc tggatgggag acgctagcgg catccttcag ggccaagttt gataaatacc     1920

accgccatca ttctgctcat cctcctcctg tttttttttt ttctcttaca ttcttttttt     1980

ttttcctgtt tatacattag aacaagataa gatttgaaat acttccttgc aaataatgtg     2040

caactcccaa ggtgaaactc aaatagaaaa agtcatctct ctggtagaaa ggatggcttt     2100

cctgtaatga ctatagagta agagtggcag caatctttcc atgccctttt cagcagaagg     2160

cacagaacag tagcgggact gccatctctg gcaagatttc aggtaaagaa tctcttctta     2220

atttctacct tcctgtttct ctgaatcagc ccataggtgt tgatgagtgg ccactcttaa     2280

agagtcactc agtatcaggg atctactgtc tttgttcaaa ggtcaaataa aaacctagtc     2340

tccttttatt ctactttcta ttcttagcta gaatgaaact cagcatatat acacttctgg     2400

acataataat attgaatagt aattaccttt actagatgaa agaaattttc attacaaact     2460

taaatcatgt aaaactcaac aactcagatt cctggacctg gtgtcctggt tgggtccaag     2520

gtgattttac agaagaaaaa aacaactcaa gcattctggt ggcaacatag agattgtagg     2580

ctgcttctaa gaaagttatt aacaatttgg aaattcctaa gtaggatgag agttagtaac     2640

tggatacgag tgaagtttat atccaagttc agactcaaag gcattattat gatttgcttc     2700

ttcccatgtc ttccatgtcc tgcttctcaa agtttttctc atccatcaca ctcctgcctt     2760

aactgctctg agtatgcatt tgttttcaat tcatctttat ttcaatctgt ttaacttttg     2820

aatcgcatgg gaatacgcac attaagttcc tttctaaaat aaggttttat gaagctgagt     2880

ttcacgataa gtgtcttgct attttttgag atgttttatg gacaaagaaa actttacaga     2940

tttatatgta ttttgctgca ccagtaaatg gaccattaac tagggcccac ctttaacaga     3000

gcaccccttt gaaagtttta taggtatgaa atatatgtag atatttgtaa agggttttaa     3060

tttttttttt ttgatggggt gctgtgtaaa tcttgtattt ataaatgtaa tgaaggtatt     3120

gacagaaaaa aatatataca acttttataa aggattgtgt actgactgaa tacatttaaa     3180

agaaaatata ttttgaaacc tgttctgcta tgaacagaga taacatatct ttttactatg     3240

ctattggttt ttaggttaag cttcctaatg cataataaat ttacagtggt tacttttaaa     3300

aaaaaaaaaa aa                                                         3312


<210>  1883
<211>  370
<212>  DNA
<213>  homo sapiens

<400>  1883
atgtcaggac gcggcaaagg aggtaagggc ctggggaaag ggggtgccaa gcgccaccgc       60

aaggtgctgc gcgacaacat ccagggtatc accaagccag ccattcggcg ccttgctcgc      120

cgcggcggcg tgaagcgcat ttctggcctc atctatgagg agacccgcgg agtgttgaag      180

gtgttcctgg agaacgtgat ccgggacgcc gtgacctaca cggagcacgc caagcgcaag      240

acggtcaccg ccatggacgt ggtctacgcg ctcaagcgcc agggccgcac cctctatggc      300

ttcggcggct aaatggcatt ttgaagccca gtcattctct aaaaaggccc tttttagggc      360

ccctaagctt                                                             370


<210>  1884
<211>  6075
<212>  DNA
<213>  homo sapiens

<400>  1884
ctctcttcct cccttcctag agagggaaca acattcatgt gacgggcccc tctgcttctc       60

ccccgcccca tcatctccag cgcgtggtgg gggaactgct ggggaaggcg attggcatcg      120

atctctccat cccttccgag gcccgacttc ggtggccacc gagtactaaa ttcacttggg      180

aataaaagaa aaacataaga aaattataag agaaaggaat tgtcttagaa gaaagaaggc      240

aagccaccat tttacccacg taaatatatg aatatatttc tgacattgag gtgttccaga      300

agatgataaa gaaatgatag cagctccaga aataccaact gattttaatc tactacagga      360

gtcagaaaca catttttctt ctgacacaga ttttgaagat atcgaaggaa aaaaccaaaa      420

gcaaggcaaa ggcaaaactt gtaaaaaagg caaaaagggc ccagcagaaa agggcaaagg      480

tggaaatgga ggaggaaaac ctccttctgg tccaaaccga atgaatggtc atcaccaaca      540

gaatggagtg gaaaacatga tgttgtttga agttgttaaa atgggcaaga gtgctatgca      600

gtcggtggta gatgattgga tagaatcata caagcatgac cgagatatag cacttcttga      660

ccttatcaac ttttttattc agtgttcagg ctgtaaagga gttgtcacag cagaaatgtt      720

tagacatatg cagaactctg agataattcg aaaaatgact gaagaattcg atgaggatag      780

tggagattat ccacttacca tggctggtcc tcagtggaag aagttcaaat ccagtttttg      840

tgaattcatt ggcgtgttag tacggcaatg tcaatatagt atcatatatg atgagtatat      900

gatggataca gtcatttcac ttcttacagg attgtctgac tcacaagtca gagcatttcg      960

acatacaagc accctggcag ctatgaagtt gatgacagct ttggtgaatg tggcactaaa     1020

tcttagcatt aatatggata atacacaaag acaatatgaa gcagaacgga ataaaatgat     1080

tggaaaacga gccaatgaga ggctagaact cctgctacaa aagcggaaag agcttcagga     1140

aaatcaagat gaaatagaaa atatgatgaa tgcaatattt aaaggagtgt ttgtacatag     1200

ataccgtgat gcgatagctg aaattcgagc tatttgcatt gaagagattg gcatttggat     1260

gaagatgtat agtgatgcct ttcttaatga cagttattta aaatatgttg gttggactat     1320

gcatgataag caaggtgaag taagactcaa atgtcttact gctctacaag ggctttatta     1380

taacaaagag cttaattcca aactggaact ttttaccagt cggttcaagg atagaattgt     1440

gtctatgacc cttgacaaag aatatgatgt tgcagtacaa gcaataaaat tactcactct     1500

tgttttacag agtagtgaag aagttctcac tgcagaagat tgtgaaaatg tctatcatct     1560

ggtttattca gctcaccggc cagtagcagt agcagctgga gaatttctct acaaaaagct     1620

cttcagtcgt agagatccag aggaggatgg aatgatgaaa agaagaggaa gacaaggtcc     1680

aaatgccaac cttgttaaga cattggtttt tttctttcta gaaagtgagt tacatgagca     1740

tgcagcatac cttgtggata gcatgtggga ctgtgctact gagctgctga aagactggga     1800

atgtatgaat agcttgttac tggaagagcc acttagtgga gaggaagcac taacagatag     1860

gcaagagagt gctctgattg aaataatgct ttgtaccatt agacaagcgg ctgaatgtca     1920

tcctcccgtg ggaagaggga caggaaaaag ggtgcttaca gcaaaggaga agaagacaca     1980

gttggatgat aggacaaaaa tcactgagct ttttgccgtg gcccttcctc agttattagc     2040

aaaatactct gtagatgcag aaaaggtgac taacttgttg cagttgcctc agtactttga     2100

tttggaaata tataccactg gacgattaga aaagcatttg gatgccttat tgcgacagat     2160

ccggaatatt gtagagaagc acacagatac agatgttttg gaagcatgtt ctaaaactta     2220

ccatgcactc tgtaatgaag agttcacaat cttcaacaga gtagatattt caagaagtca     2280

actgatagat gaattggcag ataaatttaa ccggcttctt gaagattttc tgcaagaggg     2340

tgaagaacct gatgaagatg atgcatatca ggtattgtca acattgaaga ggatcactgc     2400

ttttcataat gcccatgacc tttcaaagtg ggatttattt gcttgtaatt acaaactctt     2460

gaaaactgga atcgaaaatg gagacatgcc tgagcagatt gttattcacg cactgcagtg     2520

tactcactat gtaatccttt ggcaacttgc taagataact gaaagcagct ctacaaagga     2580

ggacttgctg cgtttaaaga aacaaatgag agtattttgt cagatatgtc aacattacct     2640

gaccaacgtg aatactactg ttaaggaaca ggccttcact attctgtgtg atattttgat     2700

gatcttcagc catcagatta tgtcaggagg gcgtgacatg ttagagccat tagtgtatac     2760

ccctgattct tcattgcagt ctgagttgct cagctttatt ttggatcatg tcttcattga     2820

acaggatgat gataataata gtgcagatgg tcagcaagag gatgaagcca gtaaaattga     2880

agctctgcac aagagaagaa atttacttgc agcattttgt aagctaattg tatatactgt     2940

ggtggagatg aatacagctg cagatatctt caaacagtat atgaagtatt ataatgacta     3000

tggagatatc atcaaagaaa caatgagtaa aacaaggcag atagacaaaa ttcagtgtgc     3060

taagaccctt attctcagtc tgcaacagct ttttaatgaa atgatacaag aaaatggcta     3120

taattttgat agatcatcct ctacatttag tggcataaaa gaacttgctc gacgttttgc     3180

tttaactttt ggacttgatc agttgaaaac aagagaagcc attgccatgc tacacaaaga     3240

tggcatagaa tttgctttta aagagcctaa tccgcaaggg gagagccatc cacctttaaa     3300

tttggcattt cttgatattc tgagtgaatt ttcttctaaa ctacttcgac aagacaaaag     3360

aacagtgtat gtttacttgg aaaagttcat gacctttcag atgtcactcc gaagagagga     3420

tgtgtggctt ccactgatgt cttaccgaaa ttctttgcta gctggtggtg atgatgacac     3480

catgtcagtc attagtggaa tcagcagccg ggggtcaaca gtacggagta aaaaatcaaa     3540

accatctaca ggaaaacgga aagtggttga gggcatgcag ctttcactca ctgaagaaag     3600

tagtagtagt gacagtatgt ggttaagcag agaacaaaca ctgcacaccc ctgttatgat     3660

gcagacacca caactcacct ccactattat gagagagccc aaaagattac ggcctgagga     3720

tagcttcatg agtgtttatc caatgcagac tgaacatcat caaacacctc ttgattataa     3780

tcggcgtggc acaagcctaa tggaagatga tgaagagcca attgtggaag atgttatgat     3840

gtcctcagaa gggaggattg aggatcttaa tgagggaatg gattttgaca ccatggatat     3900

agatttgcca ccatcaaaga acagacgaga gagaacagaa ctgaagcctg atttctttga     3960

tccagcttca attatggatg aatcagttct tggagtgtca atgttttaat accagtacac     4020

aattaaatct gtggtgaagt cattttctaa gtggaagagg aaattttaaa gtgtggtaga     4080

tacagtgaaa ttctgtacag atttttctct aaggagaata tgacatgctt atgcttacca     4140

agatcaagtg cattgagggg cagttttgtt tgcctgaata aacgtaaagg acaagtaaac     4200

aatttgatga taagctacag tttttcttag aaagtaaata ttttatttat gcgctgttag     4260

ttggcttttg aatcgattat ttcatgcttt tttttaaaaa aaaaaaaaaa caaaataaca     4320

atctgaagag gcatttggta cagatatgaa ttctcttaca tttatttact ggttgtacta     4380

aataatgatg acctctgctg gatttctgtt tacatccaga aaacaatgtt aaggatgtat     4440

ttattcccct accctgaaga aagtgtagga tagaattgtt tttagcattc taaatttaaa     4500

tgcttaaaac gtcaatcaac aaaactttgt tttaaatatt gtaattgtgg agaaaagtaa     4560

acttataagc agaactttta caattttttc atctaaaagt attttaagat atttttaaaa     4620

tccaagagct tctctatact tttcagaaat atccagatgc agtgaactgc cagaaggtaa     4680

ccagtctcaa acatgcttat cccattatca accctgaaag tttgcttgtc ctttaagata     4740

aaaatgtaat gttgtgatat tccttccagt aatgccactg tattttgtct ccaaataaaa     4800

gaagcttatt gtagtatgtt tgcagaaaaa ttctaaacaa aaattataca gcttattaga     4860

gtgtgggaat agggatctaa attttaaata aaattatata tatatataaa ttggtgctga     4920

ttttataatt gcgcagtttg tttagttttt tcttactttt aaattccaac ttaaaattat     4980

gaggtttcag aaatatattg aaagtttaac aatgtttaaa aatagaaaag catgagtgtt     5040

catgctttaa aatgattttt aaatttgtat tttatattgt tttatctatc tgtctttgca     5100

agcagtcttc aggttaaaga tacttctaac aggttacagt acatttcctc tgtatgtaaa     5160

ttagatggga taatagaatt cataacccat aatattcttt gaaagctaag ctttaaactt     5220

cattttatgt cctttcacaa ataaattagt ttaaaacaga aagtggctac ttgccatttt     5280

gacatcaact cattttgcga ggcttaggca gctagacatc gtttaaaaca aaatattaac     5340

ttatattaca tgtgtatcta tctattgtca gtcgtctctc agttcttgag gtatattatt     5400

ttaatcattc catgccttaa tatgcttgca atacaagaat atcttcagat gggtgaatac     5460

caaaaggctt tcagttttta gtcagaaatc aagcattggg ctgtggtagc caaaaaccat     5520

aggttagcta aaaagatcat gatacaatta ttttattaag tcatggttaa taacaaatga     5580

atccagactt gtctaacaga ttttccatca acaaatattg ttatgtgcaa aagtattgcc     5640

tatgttgttt tacacaccac tgcattaact agaactgctg agaggactgt atatatgatt     5700

ttaaacctaa gttgattttt tttctcactc ttgaaaggag tacttctttg tgaaagcagt     5760

tcttacagct ttgttttcaa ccagctaaaa atgttttata tattactcta acctgttgtc     5820

ctccacattc tattgtccta attgtactgt tttctgattt gtatttatgt cttgagacag     5880

taactttttg aataaaaata aacctacagt atgttgtatg ttttctcttg tactcaaagg     5940

gggagggtgg ctataaatgg tttgcaaatt tatatctatt atcacatctt ttaatgtgtt     6000

tggggaataa tttatagaga ataccatcag tttatatttt taataaatca tatgtattta     6060

caatgaaaaa aaaaa                                                      6075


<210>  1885
<211>  2514
<212>  DNA
<213>  homo sapiens

<400>  1885
gtgcccaggc gccctctccg ccgcgctccc tggtggccgc tcgctagagc acgcgcgccg       60

cagacctagg gtatttgcgg atcagcgtcc tcgcccatct catcctccac actccgcccc      120

cacccacctg ccccagctgc taagggtctt gacctttttc agaaacgtgc atcttttcca      180

gttctaattt tgcacgcttg cacgtttaaa gcaggaggga tgaattcggt agtggataaa      240

tcagcaactt taggatagct tatgcagaaa cgcgtgtatt ctctactttt ccggcagtga      300

tcggaagagc tctcaaaatt ggcttcagcc caaagggctc agatgggaat ggccaggaca      360

ccatccagca gctggaaaat gagcttcggg gcacaaagtg ggaaatggct cgtcatttgc      420

gcgaatacca ggacctcctc aacgtcaaga tggctctgga tatagaaatc gctgcgtaca      480

gaaaactcct ggagggtgaa gagactagat ttagcacatt tgcaggaagc atcactgggc      540

cactgtatac acaccgaccc ccaatcacaa tatccagtaa gattcagaaa cccaaggtgg      600

aagctcccaa gcttaaggtc caacacaaat ttgtcgagga gatcatagag gaaaccaaag      660

tggaggatga gaagtcagaa atggaagagg ccctgacagc cattacagag gaattggccg      720

tttccatgaa ggaagagaag aaagaagcag cagaagaaaa ggaagaggaa cccgaagctg      780

aagaagaaga agtagctgcc aaaaagtctc cagtgaaagc aactgcacct gaagttaaag      840

aagaggaagg ggaaaaggag gaagaagaag gccaggaaga agaggaggaa gaagatgagg      900

gagctaagtc agaccaagcc gaagagggag gatccgagaa ggaaggctct agtgaaaaag      960

aggaaggtga gcaggaagaa ggagaaacag aagctgaagc tgaaggagag gaagccgaag     1020

ctaaagagga aaagaaagtg gaggaaaaga gtgaggaagt ggctaccaag gaggagctgg     1080

tggcagatgc caaggtggaa aagccagaaa aagccaagtc tcctgtgcca aaatcaccag     1140

tggaagagaa aggcaagtct cctgtgccca agtcaccagt ggaagagaaa ggcaagtctc     1200

ctgtgcccaa gtcaccagtg gaagagaaag gcaagtctcc tgtgccgaaa tcaccagtgg     1260

aagagaaagg caagtctcct gtgtcaaaat caccagtgga agagaaagcc aaatctcctg     1320

tgccaaaatc accagtggaa gaggcaaagt caaaagcaga agtggggaaa ggtgaacaga     1380

aagaggaaga agaaaaggaa gtcaaggaag ctcccaagga agagaaggta gagaaaaagg     1440

aagagaaacc aaaggatgtg ccagagaaga agaaagctga gtcccctgta aaggaggaag     1500

ctgtggcaga ggtggtcacc atcaccaaat cggtaaaggt gcacttggag aaagagacca     1560

aagaagaggg gaagccactg cagcaggaga aagagaagga gaaagcggga ggagagggag     1620

gaagtgagga ggaagggagt gataaaggtg ccaagggatc caggaaggaa gacatagctg     1680

tcaatgggga ggtagaagga aaagaggagg tagagcagga gaccaaggaa aaaggcagtg     1740

ggagggaaga ggagaaaggc gttgtcacca atggcctaga cttgagccca gcagatgaaa     1800

agaagggggg tgataaaagt gaggagaaag tggtggtgac caaaacggta gaaaaaatca     1860

ccagtgaggg gggagatggt gctaccaaat acatcactaa atctgtaacc gtcactcaaa     1920

aggttgaaga gcatgaagag acctttgagg agaaactagt gtctactaaa aaggtagaaa     1980

aagtcacttc acacgccata gtaaaggaag tcacccagag tgactaagat ttgagtccat     2040

tgcaaaaggt taagccatat gacaatttca aaatgcatgt gattggcagc ttcaaaacag     2100

aacgggttct cccatggggg ctccagacat tgtattttac tttgtgcaat atgaggggac     2160

tgcatgcaag ctcagggtgc tccctcctca gtctttgggg gattcaaatg catgatattg     2220

tatgtacctg ggaaatttgc cgatttccta agctgttgga agggggtcac ttaagggggg     2280

atgtcttgag atgtattatg caaagtacca actgagccaa aaacaataaa cgaaacacag     2340

aactcagcct taagaaagct atatatgaat aattatgttt acctcactgg tgcatttaaa     2400

atggactttt gttcatggga gaacctcgtt gacatgcaca gtttgcaatc ttatgttgat     2460

cgatgttaaa cgtcacagca gtacttgctc aataaaggtc atattggaaa cata           2514


<210>  1886
<211>  4414
<212>  DNA
<213>  homo sapiens

<400>  1886
aattcccaga acgcactgct cgtcgcacgc aggttttcct tgttgccggg gtttgtagtt       60

cttctcgatc gtgtcagttt gtaaggcgag ggcggaagtt ggattcctgg cctgagaata      120

ttaggcgtag ttttccagtt tttggcaaag cggaaatact taaggcccct gggttgactg      180

ggttctttgt tttatctacc ggcttctgct ttacgacagg tcacaaacat gtcagacaaa      240

agtgaattaa aggctgagtt ggaacgtaag aagcagcgac tggcccaaat cagagaggaa      300

aagaagagaa aagaagaaga aaggaaaaaa aaagaaacag accagaagaa ggaagctgtt      360

gctcctgtgc aagaagaatc agatcttgaa aaaaaaagga gagaagctga agcattgctt      420

caaagcatgg ggctaactcc agaatccccc attgtttttt ctgaatactg ggtccctcct      480

cctatgtctc catcctccaa atctgtgagc actccaagtg aagctggaag ccaagactct      540

ggagatggcg ccgtgggatc taggacgctg cattgggata cagatccatc agttcttcag      600

cttcactcag attccgattt gggacgagga cctattaaac ttggaatggc taaaatcacg      660

caagtcgact ttcctcctcg agaaattgtc acgtatacaa aggaaactca gactccagtt      720

atggctcaac ccaaagaaga tgaagaggaa gatgatgatg tagtggctcc taaaccacct      780

attgaacctg aagaagagaa aactttaaag aaagatgagg aaaatgatag taaagctccc      840

cctcatgagc tgactgaaga agaaaagcaa caaatcttgc actctgagga atttttaagt      900

ttctttgacc attctacaag aattgtagaa agagctcttt ctgagcagat taacatcttc      960

tttgactata gtgggagaga tttggaagac aaagaaggag agattcaagc aggtgctaaa     1020

ctgtcattaa atcgacaatt ttttgacgaa cgttggtcaa agcatcgggt ggttagttgt     1080

ttggattggt catctcagta tccggagtta ctcgtggctt cctataacaa caatgaagat     1140

gcccctcatg agcctgatgg tgtggccctt gtatggaata tgaaatacaa aaaaactacc     1200

ccagagtatg tgtttcactg ccagtcagct gtgatgtctg ccacatttgc aaaatttcat     1260

ccaaatcttg ttgttggtgg tacatattca ggccaaattg tgctttggga taaccgtagc     1320

aataaaagaa ctccagtgca aagaactcca ctgtcagcag ctgcacacac acaccctgta     1380

tattgtgtaa atgttgttgg aacacaaaat gctcacaatc tgattagcat ctctactgat     1440

ggaaaaattt gttcatggag tctggacatg ctttcccatc cacaggatag catggagttg     1500

gttcataaac agtcaaaagc agtagctgtg acatctatgt ccttccctgt tggagatgtc     1560

aacaactttg ttgttgggag tgaagaaggt tctgtgtaca cagcatgccg ccatggcagc     1620

aaagctggaa tcagtgagat gtttgagggg catcaaggac caatcactgg catccattgt     1680

catgcagctg ttggagcagt agacttctca catctttttg tcacttcatc gtttgactgg     1740

acagtaaagc tttggacaac taagaataac aagcctttgt attcatttga agataatgca     1800

gactatgttt atgatgttat gtggtcacct acccacccag ccctgtttgc ctgtgtggat     1860

ggcatgggga gattggattt gtggaatctc aataatgaca cagaggtacc aactgccagc     1920

atttctgtgg agggtaatcc tgctcttaat cgtgtgagat ggacccattc tggcagagag     1980

attgctgtgg gtgattctga aggacagatt gttatatacg atgtgggaga gcagattgct     2040

gttccccgca atgatgaatg ggcacggttt ggccgaacac ttgcagaaat taatgcaaac     2100

cgagctgatg cagaggagga agcagctacc cgaatacctg cttagttcct gaaaagggga     2160

gtgtaactag tggatttggg aaaggttctt aagtagatcc tgagactatt tgcatgcttc     2220

tgtctaaatg ataattaaaa ggaaatttca tggattaaac catgggttta atgcagcaag     2280

gaaacttaca atgtcccttt atatataaca tgcatcttgt tttggatttg tgtcattttt     2340

taatatagct gattgacttc acagaaagca gcttttttga attctaatac ataggtgtat     2400

atttggtatt agttattttg agttcttttc aacttataac actgtataca gttatttcta     2460

aagcacagat gaaataagtt ctgcatattt ttaaataatc acagttccct gttatacaga     2520

taatgttctc actacccata atatgtagga acattgtttc tccttagccg tagtatgcat     2580

acacctatcc atgttcattc tgacatcctt tgttgtcttt ataattcatg tggtagttac     2640

ctataaataa aaacaaatat gcgttaactt ttcaaatttt catttttact ccttacaact     2700

tgaatttttc catcttttat aaaatatatt ttttccatat ctttctttaa gctcctgctg     2760

tgagcagcca tctcaaatcc tatagagctg tgtaccctaa atataccatg tggtatatac     2820

tatagatctc ccagtgcatt atgaattgat gtctagataa tctgttggtg aaaaaatttc     2880

ccctaggtta acttttgctt tactacttta tattctttcc atctaagaca tatttccttt     2940

aaaggataaa tagaaagctg cctataattt tcactgatta agaactatgt atgtgacctc     3000

actgagagta aaatctttga gagaaattga tttcatgatt tcagtagcca taaaggcaaa     3060

gtgctcaaat ggacccatac tttggcatta aaatctacat cttgagatct gttgccacag     3120

cattgtctac aagtccgaaa ggtaggtgac aaatatctaa gaatcagtat tgaaatcagt     3180

gaatttcagg aatagaggaa aggactatga tcagatcttg attttatcta ctttaaattg     3240

tctatttatt tgatcccaac cttttgtact tctgaagtgt aactgtcttt tattcaacag     3300

aacatgaact aggaagagag attagaaaac agaatgtgaa catttttctt ttaataattg     3360

taacaaagat ttgttgggag agaaatttcc aaataatgag tagtgtatag tgtaaggaat     3420

aattgacctg gaattattgg ccccaaactc tgattcttgc tgaagcatct atgagaagtg     3480

tgattttagc caagtctgtg ccgcattctt tatatgtagg aattaagttt tgatttaatg     3540

atttctgaat tttctttcag ctctactcaa ttaaggggta tcagtatgtg aaatggaata     3600

tagaaaagta ggcaattctt tacttttcta tattcagttt cataaattaa taccccataa     3660

ttgcccatta tataccaaag acaatatctc aagttatctc attgtagcag tgtctgtgag     3720

tcaaaacttc aattttagta gagtcacact ttctttatat agaaaaattc atgtactcac     3780

tactcatgta gttactgtat ctttaccttc agtttgtaaa aatgactaaa agtagggaaa     3840

acaagtgtta aaacataatg gataagaaaa ggttggaaat catatggcaa atcacatgtt     3900

cctcagcctc aaggtgtgtt tagttgtgaa agaaagaata aaattgttta aatatttcac     3960

tttttgggaa tgacttctcc cctactcccc cagaaaatgc gatgtatacc tttgcccatt     4020

caactttagt ccatattttt aggaacacac aaatttactt taaggaatta cctttaaagt     4080

tgactatata atagcaaaag agaaagtatt gagactgtca gtgttgataa agcttctagc     4140

aagattaggt tgactagaag tgcatcacag ttctttatac ttttagaact aaaagcctta     4200

taattttgaa aaatatccag ttacagaaat tgtaccttat cagttatact ttttttctga     4260

gtaagaaaac aagctatagc tttctggtta atttcttatt tttcgttgtt tggtttttgt     4320

ctttttgagt ggaacgttaa agtttattac cttcatgtta aggaatatcc agcttcacag     4380

acaattaact tgcaataaat ctctgaaata atca                                 4414


<210>  1887
<211>  5453
<212>  DNA
<213>  homo sapiens

<400>  1887
tggccagacc ctgccgcctg agagagagca cagcctggtg ggttctgggg tctacggcct       60

aggggccggg gaagtttgcg ccgccgcgac cagtgctgcg atcccgagcc gggctccagc      120

cccgaggacc aggggtcggg cgggcctgcc tacggaaccc cgcgggccag cagcagtcgt      180

ctcgcgtcct cctgcttgga aaagtgttta agcttctaaa atgtcatcta tcaagcacct      240

ggtttatgca gttattcgtt tcttacggga acaaagtcag atggacactt acacctcgga      300

tgaacaagaa agtttggaag ttgcaattca gtgcttggag acagttttta agatcagccc      360

agaagataca cacctagcag tttcacagcc tttgacagaa atgtttacca gttccttctg      420

taagaatgac gttctgcccc tttcaaactc agtgcctgaa gatgtgggaa aagctgacca      480

attaaaagat gaaggcaata accacatgaa agaagaaaat tatgctgctg cagtggattg      540

ttacacacag gcaatagaat tggatcccaa taatgcagtt tactattgca acagggctgc      600

tgctcagagc aaattaggtc actacacaga tgcgataaag gattgtgaaa aagcaatagc      660

aattgattca aagtacagca aggcctatgg gagaatgggg ctggccctca ctgccttgaa      720

taaatttgaa gaagcagtta caagttatca aaaggcatta gatcttgacc ctgaaaatga      780

ttcctataag tcaaatctga aaatagcaga acagaagtta agagaggtat ccagtcctac      840

aggaactgga ctgagctttg acatggctag cttgataaat aatccagcct tcattagtat      900

ggcggcaagt ttaatgcaga accctcaagt tcaacagcta atgtcaggaa tgatgacaaa      960

tgccattggg ggacctgctg ctggagttgg gggcctaact gacctgtcaa gcctcatcca     1020

agcgggacag cagtttgctc agcagataca gcaacaaaat cctgaactta tagagcaact     1080

gagaaatcac atccggagca gatcattcag cagcagcgct gaagagcatt cctgatttaa     1140

ccaggggctc aagcccaaga tacaaatggt ttatggctat gaatgaagta tttgttgtag     1200

atagtacccc ctccctcctt caaaaaacca aacaccatat ctgatgtgtg aaaataatgg     1260

aggaaaacct cttgtgtata ttcttaaaga ataaatctgt ttagacaata ggtttatcac     1320

aaacaaactc aaaacataac atgactcctt ttgaaatgat cactagccat gttacgtgcc     1380

aatatagcac tgggataagg ttccattttc aaacttctat catatttgta tattagactt     1440

aatagcaaag catatttatt gaactctagt agggctattt gttggtaagc tctttagctc     1500

caatttccct taagcaaagt tttttgagaa gggaaatgac ccaaaggaaa ggtttcctat     1560

gctggttgag aagaagtgta cttgccactg agcagtatgt caggaaagaa ggaatattat     1620

ctaggtttag ctttgataag tgctattagt aatgaatata taacatggga accaatgtta     1680

tctttaatgt tgcttgttct ggtgaacaga gaatcttaag agctgttaga aagtagcact     1740

tgatgcaagg gatgttttga aaagaaaaaa ttggtaatgc gaatgtatag aaagtaaagg     1800

taggatgctc aggttttctg catagttctt aactaatctt gtctgcagtt tggtattgat     1860

aatattagca tggccactta tgctaaatac acaataagat acatttagaa atccttaatg     1920

tactggttag gtcagtggta caactgtttg acttaattat cacaatttcc ccaatggtaa     1980

ccttaccttg gaaactatca aatataaata tactttaact aagccagtga cctggtccta     2040

agttaaggat tttctaaatg gtatttaatt gtgtgcccat aaacactgat tttttttaaa     2100

aagaaaactt agtaattatt tgatggataa caaaaagcat ctatcactaa cattgcttgt     2160

tcatgtaatc ttctgtgata atttggcttg gcatgccagt cttataatta acataattta     2220

aatttgatgc aatttaaata taacaggaga cttaaaatat tttattataa attagatgcc     2280

atattagtta gtggagaaaa ggggcattag gtattaattg catgggtcta actacattga     2340

tgatgagagt ttaattccaa ctagagtata ttttttgttt attaataatg aaattggtgc     2400

tgacatgtaa tgacttcaca agttttacga gggaaaactg aaaaaggaag taatataaat     2460

tttgtggggt ttttttgaga tggagtctta ctcttttgcc aggctagagt ggtgttgcaa     2520

tgtcagctca ctgcaacctc cacctcctgg attcaagtga ttctcgagcc ttaagctccc     2580

aagtagctgg gattacgggc gcccaccacc acgcccagct aatttttttt ttttttttct     2640

tgagatggag tctctctctg tcgccaggct ggagtgcagt ggcgcaatcg cggctcactg     2700

caacctctgc ctcccgggtt caagtgattc tcctgcctca gcctcctgag tagctgggat     2760

tacaggcacg tgtcaccatg cccagctaat ttttgtattt ttagtagaga cggggtttca     2820

ccatgtttgc caggattgtc tcaatctctt gacctcgtga tccgcctgcc ttggcctccc     2880

aaatgctggg attacaggcg tgagccaccg tgcctggccg ctaatttttg tttttaatgg     2940

agagagttcc accgtatcgg ccaggctggt ctcgaactcc tgacctcaag tgatctgccc     3000

atcttggccc ctcaaagtgc tgggattaga ggtgtgagcc actgtgcctg gccaggaagt     3060

aatatacaat taaatgagta ataatgcaga tgattaggcc ttatagaacc cttatcaaaa     3120

gactaattgg ccgggcgctg tggctcatgc ctgtaatccc agcactttgg gaggccaagg     3180

caggggggat cacctgaggt caggagtttg agaccagcct ggccaacatg gtgaaaccca     3240

cctctactga aaatacaaaa attagcctgg cttggtggcg ggcacccgta gtcccagcta     3300

cttgggaggc tgaagcatga gaattgctcg aacctgagag gcagaggttg cagtgagcca     3360

agattgcgcc actgcactcc agcctgggtg acagagcaag actccatttc aaaaaaaaaa     3420

aaaaaaagaa aaagagacta agagactaat tattttgtat cttgaagttt aaaatccaac     3480

ttttctcttt ctcctttgtg acattagaac agtagttcta taacttcatt gtaagaatca     3540

cctggataat tcattaaaga tgcagattca gggccacgtg ttcaattctg atacagtagg     3600

tcctgtaata aggcctagga atggccattt ttaaacagta cactaggtgg ttttgataca     3660

gatccaagga ctctaattta gaggaacact aggttagagg tttctcagac ctgcaaacac     3720

ctaagcacct gggccaaaca aagctacaac gaagatctgt atgaagatat atagttctgc     3780

agaatttaaa aagagcacaa tttaagtctt cggccctcag aagttaaatt catattccat     3840

ctaagccaac tttgattttc attaagttag aatgaactcc tagtattcca gtattacaca     3900

gaacgaagta ctactactaa cacatagaag tcattactgt gatataaaaa gcaaaataga     3960

tccttaatta aaaattagtc actcatattc agtgttgaat aagaagttaa agtttctagc     4020

ataactatct tgagtgcatt aaaaatgctt ttagagcaat aagataagct tctagctgac     4080

tgcctagaaa aacagaagat acaaattcag tgtcagaaat gaaagggaat acactacaga     4140

cactatagtt attaaaaggc taactagaaa acaccatgac caactcaagg attgtatatt     4200

taacaactta gatgaaacag attccctata ggatacaaac tagaaagctc actgtagaaa     4260

cagataacct aaacagaacc atatttatta aggaaattga gtttgtggtt aagttaaaaa     4320

ccttccagta aagaaaacta caggcccaga taacttccgt gatgaatttt accaaacact     4380

taagggagaa ataatatcaa ttctaaacaa tctcttccag gaaacagaag aggaggaaat     4440

acttcccaac tcattttatt tgaccagtat tacccagaca aagatactat aagaaaaaaa     4500

actttaaaac aatgtcttca tgtgctaaca tctgtagtta aattagccat tctttttaca     4560

tgaaataatg ggaattggta tatttcttcc atttcatttt tctatttctt tgctaatata     4620

ccacctgtaa caaattcaat ctagatgcta tctgtccact tgcctacatt tccattctat     4680

tcaagccatt tttgctcttc aagtaccttg atcactttgg aatcatagca ttgcaagcta     4740

tttcaaaaaa agttgcgtgg ttggattgtg ctagctactt ttaaatttat aaaaaatgcc     4800

ccatatattt tcttgcttgt ctgggaaata tagttgctat ctaactagaa aaataagagg     4860

gcattattaa agtaactctt taagcatcgt actaaatgtt tgacttccat taaccatatt     4920

tcttgtagta gctgtagcta ttatgatact gtgtaaaaca gaacaggttc tatatatgca     4980

aatgacattt tcatttaatg taccaaattg tgtatctaac ttttataata taggttaaac     5040

agatcctttc taagatggca ttatttaatc tttacttaaa actatgaaaa atatgtgtaa     5100

gttattgttt ataaacagaa gagactataa ttaaaatata gagcagattc caagtgacca     5160

tcattttact ttttagattt aaaacagaat gaaacagaag atttagtcat aagaagatgc     5220

ttgaaaaaca atccaagtat ccaatgcagt ggctataaaa tattatttca tcatttaatc     5280

ttaatcattt tgaaacaaag acagacttca attttacact gcttgcactt tattttgtac     5340

agacatttca ttaattatta ctcaattttg aggtgcaaac cttctgaata tagctttcat     5400

tttggaccaa acaatttgtt atggcaataa ataatgatgc attgaaaaac caa            5453


<210>  1888
<211>  3216
<212>  DNA
<213>  homo sapiens

<400>  1888
taattcctga ggggtggttg ctgcttttgc tacatgactt gccagcgccc gagcctgcgg       60

tccaactgcg ctgctgccgg agcgctcagt gccgccgctg ccgcccgcgc cccccgcgcc      120

ccgttcggca cccaccggtc gccgccgccc gccgcgccgc tgtcccgctc ccgcgccgcc      180

gccgccgttt ccccccgacg actgggtgat gctggacatg ggagatagga aagaggtgaa      240

aatgatcccc aagtcctcgt tcagcatcaa cagcctggtg cccgaggcgg tccagaacga      300

caaccaccac gcgagccacg gccaccacaa cagccaccac ccccagcacc accaccacca      360

ccaccaccat caccaccacc cgccgccgcc cgccccgcaa ccgccgccgc cgccgcagca      420

gcagcagccg ccgccgccgc cgcccccggc accgcagccc ccccagacgc ggggcgcccc      480

ggccgccgac gacgacaagg gcccccagca gctgctgctc ccgccgccgc caccgccacc      540

accggccgcc gccctggacg gggctaaagc ggacgggctg ggcggcaagg gcgagccggg      600

cggcgggccg ggggagctgg cgcccgtcgg gccggacgag aaggagaagg gcgccggcgc      660

cgggggggag gagaagaagg gggcgggcga gggcggcaag gacggggagg ggggcaagga      720

gggcgagaag aagaacggca agtacgagaa gccgccgttc agctacaacg cgctcatcat      780

gatggccatc cggcagagcc ccgagaagcg gctcacgctc aacggcatct acgagttcat      840

catgaagaac ttcccttact accgcgagaa caagcagggc tggcagaact ccatccgcca      900

caatctgtcc ctcaacaagt gcttcgtgaa ggtgccgcgc cactacgacg acccgggcaa      960

gggcaactac tggatgctgg acccgtcgag cgacgacgtg ttcatcggcg gcaccacggg     1020

caagctgcgg cgccgctcca ccacctcgcg ggccaagctg gccttcaagc gcggtgcgcg     1080

cctcacctcc accggcctca ccttcatgga ccgcgccggc tccctctact ggcccatgtc     1140

gcccttcctg tccctgcacc acccccgcgc cagcagcact ttgagttaca acggcaccac     1200

gtcggcctac cccagccacc ccatgcccta cagctccgtg ttgactcaga actcgctggg     1260

caacaaccac tccttctcca ccgccaacgg cctgagcgtg gaccggctgg tcaacgggga     1320

gatcccgtac gccacgcacc acctcacggc cgccgcgcta gccgcctcgg tgccctgcgg     1380

cctgtcggtg ccctgctctg ggacctactc cctcaacccc tgctccgtca acctgctcgc     1440

gggccagacc agttactttt tcccccacgt cccgcacccg tcaatgactt cgcagagcag     1500

cacgtccatg agcgccaggg ccgcgtcctc ctccacgtcg ccgcaggccc cctcgaccct     1560

gccctgtgag tctttaagac cctctttgcc aagttttacg acgggactgt ctgggggact     1620

gtctgattat ttcacacatc aaaatcaggg gtcttcttcc aaccctttaa tacattaaca     1680

tccctgggac cagactgtaa gtgaacgttt tacacacatt tgcattgtaa atgataatta     1740

aaaaaataag tccaggtatt ttttattaag cccccccctc ccatttctgt acgtttgttc     1800

agtctctagg gttgtttatt attctaacaa ggtgtggagt gtcagcgagg tgcaatgtgg     1860

ggagaataca ttgtagaata taaggtttgg aagtcaaatt atagtagaat gtgtatctaa     1920

atagtgactg ctttgccatt tcattcaaac ctgacaagtc tatctctaag agccgccaga     1980

tttccatgtg tgcagtatta taagttatca tggaactata tggtggacgc agaccttgag     2040

aacaacctaa attatgggga gaattttaaa atgttaaact gtaatttgta tttaaaaagc     2100

attcgtagta aaggtgccca agaaattatt ttggccattt attgttttgt ccttttcttt     2160

aaagaactgt ttttttttct tttgtttact tttagaccaa agattgggtt ctagaaaatg     2220

cacttggtat actaagtatt aaaacaaaca aaaaggaaag ttgtttcagt tggcaacact     2280

gcccattcaa ttgaatcaga aggggacaaa attaacgatt gccttcagtt tgtgttgtgt     2340

atattttgat gtatgtggtc actaacaggt cacttttatt ttttctaaat gtagtgaaat     2400

gttaatacct attgtactta taggtaaacc ttgcaaatat gtaacctgtg ttgcgcaaat     2460

gccgcataaa tttgagtgat tgttaatgtt gtcttaaaat ttcttgattg tgatactgtg     2520

gtcatatgcc cgtgtttgtc acttacaaaa atgtttacta tgaacacaca gaaataaaaa     2580

ataggctaaa ttcatatata tcttgatact tttgtctctt ttattaagta gagctaattt     2640

tttaaagacc aatcaactta tagggaattc aaaggctttt tcagccaaac taaaatttaa     2700

actgctcctt taatttgaac tgactctaaa aatgaaaata gtatttttcc ctttgtgaac     2760

aaattttaca aggagcagcc tatttaataa acactagctt taaacaaagt ataggctttt     2820

cagctgatac ctgtaagttt ctgtggatat acagcaaaaa gagatataat ttaattttct     2880

gtgcatagct ctttaccctg tgtttatttc caaatccatt aatagaatgc catttatata     2940

ttttgtttca ggtatattgt taatagagct tggcaaatta taaataaata tatgtatatg     3000

gttagataga agtgactata atgcacacat atgtaatata tatagacaca cagagccctt     3060

cagttcaggt acaatttgcg ctatgaatgc tgcaaacatt tttgtttaaa tatttgtatt     3120

tatactttct aagtcagcat ttatttttgt ggctgtttac ccacaatgaa agagttctaa     3180

taaagatgtg ctgaagttgc aatataaaaa aaaaaa                               3216


<210>  1889
<211>  5402
<212>  DNA
<213>  homo sapiens

<400>  1889
agcagttcag agccccagtt gcagacgact tgtcctgcca ccaccatgag ttctgaatgt       60

gatggtggtt ccaaagctgt gatgaatggc ttggcacctg gcagcaatgg gcaagacaaa      120

gacatggatc ctacaaaaat ctgcactggg aagggagcgg tgactctccg ggcctcgtct      180

tcctacaggg aaaccccaag cagtagccct gcgagccctc aggaaacccg gcaacacgaa      240

agcaaaccag atgagtggag gctttcttcc agtgctgatg ccaatggaaa tgcccagccc      300

tcttcactcg ctgccaaggg ctacagaagt gtgcatccca accttccttc tgacaagtcc      360

caggattcca gtcctctact aaatgaagtt tcttcttccc ttattggaac tgattcccaa      420

gcctttccat cagttagcaa gccttcatcc gcctatccct ccacaacgat tgtcaatcct      480

actattgtgc tcttgcaaca caatcgagaa cagcaaaaac gactcagtag cctttcagat      540

cctgtctcag aaagaagagt gggagagcag gactcagcac caacccagga aaaacccacc      600

tcacctggca aggctattga aaaaagagca aaggatgaca gtaggcgggt ggtgaagagc      660

actcaggact taagcgatgt ttccatggat gaagtgggca tcccactccg gaacactgag      720

agatcaaaag actggtacaa gactatgttt aaacagatcc acaaactgaa cagagatgat      780

gattcagatc tgtactctcc cagatactca ttttctgaag acacaaaatc tcccctttct      840

gtgcctcgct caaaaagtga gatgagctac attgatggtg agaaggtagt caagaggtcg      900

gccacactac ccctcccagc ccgctcttcc tcactgaagt caagctcaga aagaaatgac      960

tgggaacccc cagataagaa agtagacaca agaaaatatc gtgcagagcc caagagcatt     1020

tacgaatatc agcctggcaa gtcttccgtt ctgaccaacg aaaagatgag ctcagccatc     1080

agccctactc cggaaatttc ttcagagact cctggatata tatattcttc caacttccat     1140

gcagtgaaga gggaatcaga cggggctcct ggggatctca ctagcttgga gaatgagaga     1200

caaatttata aaagtgtctt ggaaggtggt gacatccctc ttcagggcct gagtgggctc     1260

aagcgaccat ccagctctgc ttccactaaa gattcagaat cgccaagaca ttttatacca     1320

gctgattact tggaatccac ggaagaattt attcgaagac gtcatgatga taaagagatg     1380

agacctgcca gagccaaatt tgactttaaa gctcagacac taaaggagct tcctctgcag     1440

aagggagata ttgtttacat ttataagcaa attgatcaga actggtatga aggagaacac     1500

cacggccggg tgggaatctt cccacgcacc tacatcgagc ttcttcctcc tgctgagaag     1560

gcacagccca aaaagttgac accagtgcag gttttggaat atggagaagc tattgctaag     1620

tttaacttta atggtgatac acaagtagaa atgtccttca gaaagggtga gaggatcaca     1680

ctgctccggc aggtagatga gaactggtac gaagggagga tcccggggac atcccgacaa     1740

ggcatcttcc ccatcaccta cgtggatgtg atcaagcgac cactggtgaa aaaccctgtg     1800

gattacatgg acctgccttt ctcctcctcc ccaagtcgca gtgccactgc aagcccacag     1860

caacctcaag cccagcagcg aagagtcacc cccgacagga gtcaaacctc acaagattta     1920

tttagctatc aagcattata tagctatata ccacagaatg atgatgagtt ggaactccgc     1980

gatggagata tcgttgatgt catggaaaaa tgtgacgatg gatggtttgt tggtacttca     2040

agaaggacaa agcagtttgg tacttttcca ggcaactatg taaaaccttt gtatctataa     2100

gaagactgaa aaccatggag attattttta ttggaggagg aagcatcatt catgaaccga     2160

tctttttagt tgagtcagta ggaaaattaa tacagtggat aaagtaagaa gcaaaagaca     2220

gggacagaga agtgttgtgt ttaaaaccca agcctgtcta aggttactgt gtattagaca     2280

gggccgaact agtgtgctga gcaaaaagaa ttgaagcaaa ttgtatttac ttagccgctt     2340

ctgggagcca cttcagcctt tcccctcccc tccacttctt gggtaatctg acctgaagca     2400

tagtccagga gcagagttag ccagaaatgc ctcctgctgc cccagcctta gagagctccc     2460

atctcaatca ttgagcctga aggcttcaag cccaagaatg caacaagacc cccagcctac     2520

atttctcagc tcccctggag ccagctgatc ctgtaacgct gctggaggtc agtctgagct     2580

accaagactg tccctagaca aaggtggagt cccccacact gcccaagacc aaatccctca     2640

ctcaacctgc tgaggtgtgg atggggaaac agaggcaaaa ctgaggcacc tgatgcattc     2700

agcctgctgt gcagcagtgc cattgactgc cctgatgttc agagagaaac gcacacaagg     2760

tttgcccatg agaattgggg agcagatggc caagcagata ggttatgtct gttttctgag     2820

tgatgaagtc aggaagccct gtggctctgg aggccacttg tggttcattc ttttcccata     2880

tccttggctt ttagaaatgg ttaccttcag gacagtgcag ctgcatttat cagagcacta     2940

ttgctaagtt ttcttttctg gcttgtgttt ttctgggaca gtttagaatt gggaggccta     3000

ttctcataga acaccaaaaa tgatgttcag tgattcattt aacatacacc aatgtactct     3060

ggctgctggg gggacaacca taagcaagac atgcccaggg tttgccgtgg ctccagatct     3120

actccctgta ggagttcaag gatcacacaa acggtagtaa ccagggttgt gaatctgagt     3180

acaccctggc aaggcttctc ttcagactga agcagcaatt ctgccactac cagcagcaac     3240

caggacgtct gttctttgtg ggggccagat cagaagagag aggcccctgt gacgcccggg     3300

ctgcttggtc acaactctgt ccaattcaag gatgtttatc ggcctctctt agatcctgag     3360

tgagacaaat acagaaatga cccattccct gcccaccaga aactcagagg tgattgggga     3420

gactgacaca ggaaaatgaa cttaatcaag agagactgtg atatgtgcta agaagggtgt     3480

gagggaggga gagatgaatt ttccctggag ggatcctaga aagcattgtc atattgccat     3540

ctccattagc tcacttttaa acaactaggg tgctggaaga acctttgtct gagggtagtt     3600

catagctgga aatacttgga atattttcca gagtctctaa actctcatct tcccccacag     3660

atacacatcc aagctcacaa ataggagtag caattctagg tggtagggtt gtgtacggaa     3720

cccctggctg tctgcatata tctcagaatt accccaggac cattgtccca aagtctagag     3780

tctttacagg taggcaaaat ttgttttcaa tgcctgtgcc tcagctgctg tcacaaatac     3840

ccatcttagg atcccatcag cttcccatcc cccaccagac agccacagta ccctcacttt     3900

ctccctattg ttctttcaaa tcctgttctc aggaaagaaa ctgccactaa ttcattcaca     3960

ctaaggtgta aatgattgat aataggaatg agttacctct tcccacagac atttgttttt     4020

aagtatgaca gagcagggcc ttaatcccaa gggaaaaggt tatggaactg gagggggtga     4080

gctttctggg tagaaggaga cttcctgaat ttccttaaaa cccagtaaga gtaagacctg     4140

ttgttttgga aggtctgctc caccatctaa gagcactgtt tttttttttt tgttgttgtt     4200

gttgttttac ggtctctgag ggaatatagt aaaaatgcat atgcacgtgc aatttgcacg     4260

gcagcatttc accgattgtg gactgtattg gctaatgtgt ttcctggtct ttagatgcaa     4320

accattaata acactatctt atctcatagt tttttcaggg gtgcttcttg attagtaggg     4380

aattttgaac acctctttaa atacagctag aaaataaaac caatttgtaa agccacattt     4440

gcatatgatg ccagcctcac gcatttgtat atctccagaa attcaggtat gcctcaccaa     4500

tttgcccgtc tttaataaaa tcttgtgtta aaatttgcat cacgtcgcct tcctatgtat     4560

gacgaaacaa gaaacagaga tttccaattg ctcttttgtc ttcagacatt tagtaatata     4620

aagtacctat ttttatgctg aaatgtttat acaggtttat taatagcaag tgcaactaac     4680

tggcggcatg ccttgcaaca cattttgata tattagccat gcttccgggt aaaggcaagc     4740

cccaaactcc ttatcttttg cagtctctct gggatcagta aaagaaaaaa aaaataatgt     4800

gcttaagaag tgggactgta aatatgtata tttaactttg tatagcccat gtacctacct     4860

tgtatagaaa aataatttta aaaatttgaa tggaaggggg taaaggaagt catgaagttt     4920

ttttgcattt ttatttaaat gaaggaattc caaataactc acctacagat ttttagcaca     4980

aaaatagcca ttgtaaagtg ttaaaattta cgataagtat tctattgggg aggaaaggta     5040

actctgatct cagttacagt ttttttttcc tttttaattt cattattttg ggtttttggt     5100

ttttgcagtc ctatttatct gcagtcgtat taagtcctat tgctagaata ggttactaca     5160

aaaaaggtta tattctgaaa gaaaaataac tgacattata tataaccaat taatttaaag     5220

tattgccatt taaattacac actgagagca tgtcctatgc agacatagat ttttctgttc     5280

atttattttt cttcattgca gtggattgat ttgataaata gatgtgttga attactacat     5340

ttgctgtaca tattatttaa taaactttat tcagaattgc gtggcaaaaa aaaaaaaaaa     5400

aa                                                                    5402


<210>  1890
<211>  2911
<212>  DNA
<213>  homo sapiens

<400>  1890
ggtgctcggc tcgcggggac tggcctcctt cggcagctgg aggcggtcac tcacgctggg       60

ctaggagctg aggcgagaag ggccatgcgg acggcgaggg agtccagagc cttgagcccg      120

gtgctcctcc ctcgcgcagc ggtggctctg cggccgctgg agtaaacact gcctttgttc      180

cctagcgcct cgtctttcgt cgccccgtgc cctcacgccg ccgggctctg gccggcccgc      240

cctcggtcct tgaaccccat ttcggctcgt gccgtgcgga tgcagctgcc gggcctgggt      300

ttgggcattg agcgggagga ggaggaggag cggcggcgcc tgggcggcat gcgatgggga      360

actgctgctg gacgcagtgc ttcggactgc ttcgcaagga agcggggcgg ctgcagcgag      420

taggcggcgg cggaggatcc aagtatttta gaacatgctc aagaggtgag cacttaacaa      480

tagagtttga gaatctagta gaaagtgatg aaggggagag cccaggaagc agtcataggc      540

ctcttactga ggaagaaatt gttgacctaa gagaaaggca ttatgattcc attgccgaaa      600

aacaaaaaga tcttgataag aaaattcaaa aagagttagc cttacaagaa gagaagttaa      660

gactagaaga agaagcttta tacgctgcac agcgtgaagc agccagggca gcaaagcagc      720

gaaagctctt ggagcaagaa aggcagagaa ttgtgcagca atatcatcct tccaacaatg      780

gagaatatca aagttcagga ccagaagatg acttcgaatc ttgtttgaga aatatgaagt      840

cacagtatga agtttttcga agtagtagac tctcatcaga tgctacagtt ttgacaccaa      900

atacagaaag cagttgtgat ttaatgacca aaactaaatc aactagtgga aatgacgaca      960

gcacatcctt agatctagag tgggaagatg aagaaggaat gaatagaatg cttccaatga     1020

gagaacgttc caaaacagag gaagacattc tacgggcagc acttaagtat agcaacaaga     1080

agactggaag taatcctaca tcagcctctg atgattccaa tgggctggag tgggaaaatg     1140

attttgttag tgccgaaatg gatgataatg gaaattccga gtattctgga tttgtaaatc     1200

ctgtattaga actgtctgat tctggcataa ggcattctga cacagatcaa cagactcgat     1260

agggtaaaat tgtgtgacct tgtttatcag ttatgaccaa atgttaaaaa ccaactagaa     1320

tgtataagtg attgtgctta gcctttttgt aagggagatg tgtaagaaac catgttgtaa     1380

atgcttattt tattacaaag gagtagggat gataggatct gaattgatac agaattaagt     1440

gcaatttcat catctgcctt ctgcttttca agaccaattt aatggtcctg tcatgttact     1500

gattaaattt actttgtctt gtctttatag catttctgtt tactatggta gatttccact     1560

ttcaattttt aaaattaatt ttactttgaa tgatttatga agcctatttc attgtctaac     1620

tatgaaaata ttaagacttt tttgttaatt ctcagccgat gtgaaggaag catgaggagg     1680

gatcgtcaga ttcagattta gaatagtgtt cccgtttcca gcattattta tttctatgac     1740

ttctttggat tttattatct aatagtaagt acagttgatg tgggtagatg actctaagaa     1800

atgctgaagt atcggcatta catgtgttta tttacatgtc ctagtatgat aatgttgatt     1860

caatctgaac aaaagataat ataaaaataa cccttcagag tttggacatt tcaagttggt     1920

aataataaaa aataatattt aagaagatat atatatatat atatttagtt ttttccactt     1980

cattttacat gccactatat tgactttaat tgatatacag tattaagttt ttaggtgcca     2040

ttatttttaa aaaattctat atttccaatg aacgatgtta gattttacac agaacatatt     2100

ctctgcatga tttcagaaaa gaaaatctaa aaaggtaata cgggtatttc aaataaaatc     2160

ctttctggta tgaaaggctc cattgatttt attaagcctt cctttacctt gtagtacaag     2220

gtgctttaat gggatagaac taagcatatc aatatctata actgcatttt gtgctagaca     2280

attactgttc ttttctctaa aatgtatatg tcaatttaca aggccaggga tagaaaacac     2340

tccataattg ctttccttga ttttgctgag gatttggtat gattttagta agcaaactgt     2400

tttttggttt ttccttaatg tttttaattt tttttcctct tgcaacaatg acggtgcatg     2460

ttcttataaa tataggaagg tccagatata aatagtaacc taaagttctt gctgtgctta     2520

aaaaaaaaaa tcatgtggcc ctttcaatat ttgaactgct aagcaatgac atctgtagtt     2580

ttatctcctt ttttatgtca tagaaattaa tatgatactt taaatatgta aatataatac     2640

attaggtaat gctattattt atatctgtct taacataatt taagttgtag ctgtgtcttg     2700

gaaatatttt taaggtaatc tatattcaca ttgcctgtgt taatgctttt taaagtttgt     2760

atacatcaga tgtatatttt tggtttggca taagctacga ttgtaatttt tcttggcttt     2820

ttgttcataa agaatttttt gaaggaatgg taacaaatgg taatttacaa atggttgtga     2880

ataaacacat ttttacactt aaaggtaaaa a                                    2911


<210>  1891
<211>  10814
<212>  DNA
<213>  homo sapiens

<400>  1891
agtcttccca cctcccacaa gatggcggag ggcaagtagc aagggggcgg ggtgtggccg       60

ccggaagcct agccgctgct cgggggggac ctgcgggctc aggcccggga gctgcggacc      120

gaggttggct cgatgctgtt cccaggtact gttgttggct gttggtgagg aaggtgaagc      180

actcagttgc cttctcgggc ctcggcgccc cctatgtacg cctccctggg ctcgggtccg      240

gtcgcccctt tgcccgcttc tgtaccaccc tcagttctcg ggtcctggag caccggcggc      300

agcaggagct gcgtccggca ggagacgaag agcccgggcg gcgctcgtac ttctggccac      360

tgggcgagcg tctggcagga agtacttaaa caactacaag gaagtattga agatgaagct      420

atggcttctt ctggacagat tgatttatta gagcgtctta aagagcttaa cttagatagc      480

agtaatttcc ctggagtaaa actgcggtca aaaatgtccc tccgttctta tggaagccgg      540

gaaggatctg tatcaagccg ttctggagag tgcagtcctg ttcctatggg ttcatttcca      600

agaagagggt ttgtaaatgg aagcagagaa agtactggat atttagaaga acttgagaaa      660

gagaggtcat tgcttcttgc tgatcttgac aaagaagaaa aggaaaaaga ctggtattac      720

gctcaacttc agaatctcac taaaagaata gatagtcttc ctttaactga aaatttttcc      780

ttacaaacag atatgaccag aaggcaattg gaatatgaag caaggcaaat cagagttgcg      840

atggaagaac aactaggtac ctgccaggat atggaaaaac gagcacagag gtcatctcag      900

aacaagcatg aaaccggctc acatgatgct gagcggcaga atgaaggtca aggagtggga      960

gaaatcaaca tggcaacttc tggtaatggt cagggttcaa ctacacgaat ggaccatgaa     1020

acagccagtg ttttgagttc tagtagcaca cactctgcac ctcgaaggct gacaagtcat     1080

ctgggaacca aggtggaaat ggtgtattca ttgttgtcaa tgcttggtac tcatgataag     1140

gatgatatgt cgcgaacttt gctagctatg tctagctccc aagacagctg tatatccatg     1200

cgacagtctg gatgtcttcc tctcctcatc cagcttttac atggcaatga caaagactct     1260

gtattgttgg gaaattcccg gggcagtaaa gaggctcggg ccagggccag tgcagcactc     1320

cacaacatca ttcactcaca gcctgatgac aagagaggca ggcgtgaaat ccgagtcctt     1380

catcttttgg aacagatacg cgcttactgt gaaacctgtt gggagtggca ggaagctcat     1440

gaaccaggca tggaccagga caaaaatcca atgccagctc ctgttgaaca tcagatctgt     1500

cctgctgtgt gtgttctaat gaaactttca tttgatgaag agcatagaca tgcaatgaat     1560

gaactagggg gactacaggc cattgcagaa ttattgcaag tggactgtga aatgtatggg     1620

cttactaatg accactacag tattacacta agacgatatg ctggaatggc tttgacaaac     1680

ttgacttttg gagatgtagc caacaaggct acgctatgct ctatgaaagg ctgcatgaga     1740

gcacttgtgg cccaactaaa atctgaaagt gaagacttac agcaggttat tgcgagtgtt     1800

ttgaggaatt tgtcttggcg agcagatgta aatagtaaaa agacgttgcg agaagttgga     1860

agtgtgaaag cattgatgga atgtgcttta gaagttaaaa aggaatcaac cctcaaaagc     1920

gtattgagtg ccttatggaa tttgtcagca cattgcactg agaataaagc tgatatatgt     1980

gctgtagatg gtgcacttgc atttttggtt ggcactctta cttaccggag ccagacaaac     2040

actttagcca ttattgaaag tggaggtggg atattacgga atgtgtccag cttgatagct     2100

acaaatgagg accacaggca aatcctaaga gagaacaact gtctacaaac tttattacaa     2160

cacttaaaat ctcatagttt gacaatagtc agtaatgcat gtggaacttt gtggaatctc     2220

tcagcaagaa atcctaaaga ccaggaagca ttatgggaca tgggggcagt tagcatgctc     2280

aagaacctca ttcattcaaa gcacaaaatg attgctatgg gaagtgctgc agctttaagg     2340

aatctcatgg caaataggcc tgcgaagtac aaggatgcca atattatgtc tcctggctca     2400

agcttgccat ctcttcatgt taggaaacaa aaagccctag aagcagaatt agatgctcag     2460

cacttatcag aaacttttga caatatagac aatttaagtc ccaaggcatc tcatcgtagt     2520

aagcagagac acaagcaaag tctctatggt gattatgttt ttgacaccaa tcgacatgat     2580

gataataggt cagacaattt taatactggc aacatgactg tcctttcacc atatttgaat     2640

actacagtgt tacccagctc ctcttcatca agaggaagct tagatagttc tcgttctgaa     2700

aaagatagaa gtttggagag agaacgcgga attggtctag gcaactacca tccagcaaca     2760

gaaaatccag gaacttcttc aaagcgaggt ttgcagatct ccaccactgc agcccagatt     2820

gccaaagtca tggaagaagt gtcagccatt catacctctc aggaagacag aagttctggg     2880

tctaccactg aattacattg tgtgacagat gagagaaatg cacttagaag aagctctgct     2940

gcccatacac attcaaacac ttacaatttc actaagtcgg aaaattcaaa taggacatgt     3000

tctatgcctt atgccaaatt agaatacaag agatcttcaa atgatagttt aaatagtgtc     3060

agtagtagtg atggttatgg taaaagaggt caaatgaaac cctcgattga atcctattct     3120

gaagatgatg aaagtaagtt ttgcagttat ggtcaatacc cagccgacct agcccataaa     3180

atacatagtg caaatcatat ggatgataat gatggagaac tagatacacc aataaattat     3240

agtcttaaat attcagatga gcagttgaac tctggaaggc aaagtccttc acagaatgaa     3300

agatgggcaa gacccaaaca cataatagaa gatgaaataa aacaaagtga gcaaagacaa     3360

tcaaggaatc aaagtacaac ttatcctgtt tatactgaga gcactgatga taaacacctc     3420

aagttccaac cacattttgg acagcaggaa tgtgtttctc catacaggtc acggggagcc     3480

aatggttcag aaacaaatcg agtgggttct aatcatggaa ttaatcaaaa tgtaagccag     3540

tctttgtgtc aagaagatga ctatgaagat gataagccta ccaattatag tgaacgttac     3600

tctgaagaag aacagcatga agaagaagag agaccaacaa attatagcat aaaatataat     3660

gaagagaaac gtcatgtgga tcagcctatt gattatagtt taaaatatgc cacagatatt     3720

ccttcatcac agaaacagtc attttcattc tcaaagagtt catctggaca aagcagtaaa     3780

accgaacata tgtcttcaag cagtgagaat acgtccacac cttcatctaa tgccaagagg     3840

cagaatcagc tccatccaag ttctgcacag agtagaagtg gtcagcctca aaaggctgcc     3900

acttgcaaag tttcttctat taaccaagaa acaatacaga cttattgtgt agaagatact     3960

ccaatatgtt tttcaagatg tagttcatta tcatctttgt catcagctga agatgaaata     4020

ggatgtaatc agacgacaca ggaagcagat tctgctaata ccctgcaaat agcagaaata     4080

aaagaaaaga ttggaactag gtcagctgaa gatcctgtga gcgaagttcc agcagtgtca     4140

cagcacccta gaaccaaatc cagcagactg cagggttcta gtttatcttc agaatcagcc     4200

aggcacaaag ctgttgaatt ttcttcagga gcgaaatctc cctccaaaag tggtgctcag     4260

acacccaaaa gtccacctga acactatgtt caggagaccc cactcatgtt tagcagatgt     4320

acttctgtca gttcacttga tagttttgag agtcgttcga ttgccagctc cgttcagagt     4380

gaaccatgca gtggaatggt aagtggcatt ataagcccca gtgatcttcc agatagccct     4440

ggacaaacca tgccaccaag cagaagtaaa acacctccac cacctcctca aacagctcaa     4500

accaagcgag aagtacctaa aaataaagca cctactgctg aaaagagaga gagtggacct     4560

aagcaagctg cagtaaatgc tgcagttcag agggtccagg ttcttccaga tgctgatact     4620

ttattacatt ttgccacgga aagtactcca gatggatttt cttgttcatc cagcctgagt     4680

gctctgagcc tcgatgagcc atttatacag aaagatgtgg aattaagaat aatgcctcca     4740

gttcaggaaa atgacaatgg gaatgaaaca gaatcagagc agcctaaaga atcaaatgaa     4800

aaccaagaga aagaggcaga aaaaactatt gattctgaaa aggacctatt agatgattca     4860

gatgatgatg atattgaaat actagaagaa tgtattattt ctgccatgcc aacaaagtca     4920

tcacgtaaag caaaaaagcc agcccagact gcttcaaaat tacctccacc tgtggcaagg     4980

aaaccaagtc agctgcctgt gtacaaactt ctaccatcac aaaacaggtt gcaaccccaa     5040

aagcatgtta gttttacacc gggggatgat atgccacggg tgtattgtgt tgaagggaca     5100

cctataaact tttccacagc tacatctcta agtgatctaa caatcgaatc ccctccaaat     5160

gagttagctg ctggagaagg agttagagga ggggcacagt caggtgaatt tgaaaaacga     5220

gataccattc ctacagaagg cagaagtaca gatgaggctc aaggaggaaa aacctcatct     5280

gtaaccatac ctgaattgga tgacaataaa gcagaggaag gtgatattct tgcagaatgc     5340

attaattctg ctatgcccaa agggaaaagt cacaagcctt tccgtgtgaa aaagataatg     5400

gaccaggtcc agcaagcatc tgcgtcttct tctgcaccca acaaaaatca gttagatggt     5460

aagaaaaaga aaccaacttc accagtaaaa cctataccac aaaatactga atataggaca     5520

cgtgtaagaa aaaatgcaga ctcaaaaaat aatttaaatg ctgagagagt tttctcagac     5580

aacaaagatt caaagaaaca gaatttgaaa aataattcca aggtcttcaa tgataagctc     5640

ccaaataatg aagatagagt cagaggaagt tttgcttttg attcacctca tcattacacg     5700

cctattgaag gaactcctta ctgtttttca cgaaatgatt ctttgagttc tctagatttt     5760

gatgatgatg atgttgacct ttccagggaa aaggctgaat taagaaaggc aaaagaaaat     5820

aaggaatcag aggctaaagt taccagccac acagaactaa cctccaacca acaatcagct     5880

aataagacac aagctattgc aaagcagcca ataaatcgag gtcagcctaa acccatactt     5940

cagaaacaat ccacttttcc ccagtcatcc aaagacatac cagacagagg ggcagcaact     6000

gatgaaaagt tacagaattt tgctattgaa aatactccgg tttgcttttc tcataattcc     6060

tctctgagtt ctctcagtga cattgaccaa gaaaacaaca ataaagaaaa tgaacctatc     6120

aaagagactg agccccctga ctcacaggga gaaccaagta aacctcaagc atcaggctat     6180

gctcctaaat catttcatgt tgaagatacc ccagtttgtt tctcaagaaa cagttctctc     6240

agttctctta gtattgactc tgaagatgac ctgttgcagg aatgtataag ctccgcaatg     6300

ccaaaaaaga aaaagccttc aagactcaag ggtgataatg aaaaacatag tcccagaaat     6360

atgggtggca tattaggtga agatctgaca cttgatttga aagatataca gagaccagat     6420

tcagaacatg gtctatcccc tgattcagaa aattttgatt ggaaagctat tcaggaaggt     6480

gcaaattcca tagtaagtag tttacatcaa gctgctgctg ctgcatgttt atctagacaa     6540

gcttcgtctg attcagattc catcctttcc ctgaaatcag gaatctctct gggatcacca     6600

tttcatctta cacctgatca agaagaaaaa ccctttacaa gtaataaagg cccacgaatt     6660

ctaaaaccag gggagaaaag tacattggaa actaaaaaga tagaatctga aagtaaagga     6720

atcaaaggag gaaaaaaagt ttataaaagt ttgattactg gaaaagttcg atctaattca     6780

gaaatttcag gccaaatgaa acagcccctt caagcaaaca tgccttcaat ctctcgaggc     6840

aggacaatga ttcatattcc aggagttcga aatagctcct caagtacaag tcctgtttct     6900

aaaaaaggcc caccccttaa gactccagcc tccaaaagcc ctagtgaagg tcaaacagcc     6960

accacttctc ctagaggagc caagccatct gtgaaatcag aattaagccc tgttgccagg     7020

cagacatccc aaataggtgg gtcaagtaaa gcaccttcta gatcaggatc tagagattcg     7080

accccttcaa gacctgccca gcaaccatta agtagaccta tacagtctcc tggccgaaac     7140

tcaatttccc ctggtagaaa tggaataagt cctcctaaca aattatctca acttccaagg     7200

acatcatccc ctagtactgc ttcaactaag tcctcaggtt ctggaaaaat gtcatataca     7260

tctccaggta gacagatgag ccaacagaac cttaccaaac aaacaggttt atccaagaat     7320

gccagtagta ttccaagaag tgagtctgcc tccaaaggac taaatcagat gaataatggt     7380

aatggagcca ataaaaaggt agaactttct agaatgtctt caactaaatc aagtggaagt     7440

gaatctgata gatcagaaag acctgtatta gtacgccagt caactttcat caaagaagct     7500

ccaagcccaa ccttaagaag aaaattggag gaatctgctt catttgaatc tctttctcca     7560

tcatctagac cagcttctcc cactaggtcc caggcacaaa ctccagtttt aagtccttcc     7620

cttcctgata tgtctctatc cacacattcg tctgttcagg ctggtggatg gcgaaaactc     7680

ccacctaatc tcagtcccac tatagagtat aatgatggaa gaccagcaaa gcgccatgat     7740

attgcacggt ctcattctga aagtccttct agacttccaa tcaataggtc aggaacctgg     7800

aaacgtgagc acagcaaaca ttcatcatcc cttcctcgag taagcacttg gagaagaact     7860

ggaagttcat cttcaattct ttctgcttca tcagaatcca gtgaaaaagc aaaaagtgag     7920

gatgaaaaac atgtgaactc tatttcagga accaaacaaa gtaaagaaaa ccaagtatcc     7980

gcaaaaggaa catggagaaa aataaaagaa aatgaatttt ctcccacaaa tagtacttct     8040

cagaccgttt cctcaggtgc tacaaatggt gctgaatcaa agactctaat ttatcaaatg     8100

gcacctgctg tttctaaaac agaggatgtt tgggtgagaa ttgaggactg tcccattaac     8160

aatcctagat ctggaagatc tcccacaggt aatactcccc cggtgattga cagtgtttca     8220

gaaaaggcaa atccaaacat taaagattca aaagataatc aggcaaaaca aaatgtgggt     8280

aatggcagtg ttcccatgcg taccgtgggt ttggaaaatc gcctgaactc ctttattcag     8340

gtggatgccc ctgaccaaaa aggaactgag ataaaaccag gacaaaataa tcctgtccct     8400

gtatcagaga ctaatgaaag ttctatagtg gaacgtaccc cattcagttc tagcagctca     8460

agcaaacaca gttcacctag tgggactgtt gctgccagag tgactccttt taattacaac     8520

ccaagcccta ggaaaagcag cgcagatagc acttcagctc ggccatctca gatcccaact     8580

ccagtgaata acaacacaaa gaagcgagat tccaaaactg acagcacaga atccagtgga     8640

acccaaagtc ctaagcgcca ttctgggtct taccttgtga catctgttta aaagagagga     8700

agaatgaaac taagaaaatt ctatgttaat tacaactgct atatagacat tttgtttcaa     8760

atgaaacttt aaaagactga aaaattttgt aaataggttt gattcttgtt agagggtttt     8820

tgttctggaa gccatatttg atagtatact ttgtcttcac tggtcttatt ttgggaggca     8880

ctcttgatgg ttaggaaaaa aatagtaaag ccaagtatgt ttgtacagta tgttttacat     8940

gtatttaaag tagcatccca tcccaacttc ctttaattat tgcttgtctt aaaataatga     9000

acactacaga tagaaaatat gatatattgc tgttatcaat catttctaga ttataaactg     9060

actaaactta catcagggaa aaattggtat ttatgcaaaa aaaaatgttt ttgtccttgt     9120

gagtccatct aacatcataa ttaatcatgt ggctgtgaaa ttcacagtaa tatggttccc     9180

gatgaacaag tttacccagc ctgctttgct ttactgcatg aatgaaactg atggttcaat     9240

ttcagaagta atgattaaca gttatgtggt cacatgatgt gcatagagat agctacagtg     9300

taataattta cactattttg tgctccaaac aaaacaaaaa tctgtgtaac tgtaaaacat     9360

tgaatgaaac tattttacct gaactagatt ttatctgaaa gtaggtagaa tttttgctat     9420

gctgtaattt gttgtatatt ctggtatttg aggtgagatg gctgctcttt tattaatgag     9480

acatgaattg tgtctcaaca gaaactaaat gaacatttca gaataaatta ttgctgtatg     9540

taaactgtta ctgaaattgg tatttgtttg aagggtcttg tttcacattt gtattaataa     9600

ttgtttaaaa tgcctctttt aaaagcttat ataaattttt ttcttcagct tctatgcatt     9660

aagagtaaaa ttcctcttac tgtaataaaa acaattgaag aagactgttg ccacttaacc     9720

attccatgcg ttggcactta tctattcctg aaatttcttt tatgtgatta gctcatcttg     9780

atttttaata tttttccact taaacttttt tttcttactc cactggagct cagtaaaagt     9840

aaattcatgt aatagcaatg caagcagcct agcacagact aagcattgag cataataggc     9900

ccacataatt tcctctttct taatattata gaattctgta cttgaaattg attcttagac     9960

attgcagtct cttcgaggct ttacagtgta aactgtcttg ccccttcatc ttcttgttgc    10020

aactgggtct gacatgaaca ctttttatca ccctgtatgt tagggcaaga tctcagcagt    10080

gaagtataat cagcactttg ccatgctcag aaaattcaaa tcacatggaa ctttagaggt    10140

agatttaata cgattaagat attcagaagt atattttaga atccctgcct gttaaggaaa    10200

ctttatttgt ggtaggtaca gttctggggt acatgttaag tgtcccctta tacagtggag    10260

ggaagtcttc cttcctgaag gaaaataaac tgacacttat taactaagat aatttactta    10320

atatatcttc cctgatttgt tttaaaagat cagagggtga ctgatgatac atgcatacat    10380

atttgttgaa taaatgaaaa tttattttta gtgataagat tcatacactc tgtatttggg    10440

gagggaaaac ctttttaagc atggtggggc actcagatag gagtgaatac acctacctgg    10500

tgccttgaaa atcacatcaa gtagttaatt atctacccct tacctgtgtt tataacttcc    10560

aggtaatgag aatgattttt tttaaagcta aaatgccagt aaataaaagt gctatgactt    10620

gagctaagat atttgactcc aatgcctgta ctgtgtctac tgcaccactt tgtaaacact    10680

tcaatttact atctttgaaa tgattgacct ttaaattttt gccaaatgtt atctgaaatt    10740

gtctatgaat accatctact tctgttgttt tcccaggctt ccataaacaa tggagataca    10800

tgcaaaaaaa aaaa                                                      10814


<210>  1892
<211>  7155
<212>  DNA
<213>  homo sapiens

<400>  1892
gggctgggga tcggggggcg ccgagtttga ctagtttggg ggcggctggg cgcttggcgt       60

tcctcccgcc gcccgctgcg ccccgcaagc cgcgcccctg gcgggctaag tgagtcccgc      120

ccgctcccgc ggggacccgc actggaggct gggcggctct cggcgaaagt tggccgctca      180

cagactggca ggcgggcggg cggccgcagc catggagccc cgcagcatgg agtacttctg      240

cgcccaggtg cagcagaagg acgtcggcgg ccggctgcag gtcggccagg agctcctgct      300

ctaccttggc gcccccggcg ccatctcgga cctggaggag gacctgggcc gcctaggcaa      360

gacagtcgac gcgctcaccg gctgggtggg ttcgagcaac taccgggtat cattaatggg      420

attggaaatt ttaagtgcct ttgtggacag attatcaaca cgctttaaat cctatgtagc      480

aatggttatt gtagctttaa tagacagaat gggagatgcc aaagacaagg ttcgagatga      540

agctcagact ctgatattga agttaatgga tcaagtagca ccacctatgt acatttggga      600

gcagttggct tctggtttta aacacaagaa ttttcgatct cgagaaggcg tgtgtctgtg      660

tcttattgaa accttaaaca tttttggggc tcagccacta gtcatcagca aattgatacc      720

acatttgtgt atcctgtttg gagactccaa cagtcaggtg agagatgctg caatattggc      780

tatagtggag atttatagac atgtgggaga aaaagtgagg atggatcttt ataagagagg      840

aattccccct gctagattag aaatgatatt tgccaaattt gatgaagtgc aaagttcagg      900

cggtatgatt ttgagtgtct gcaaagataa aagcttcgat gatgaagaat cagtggatgg      960

aaataggcca tcatcagctg catcagcctt caaggttcct gcacctaaaa catccggaaa     1020

tcctgccaac agtgcaagga agcctggttc agcaggtggc cctaaggttg gagcaggtgc     1080

ttctaaggaa ggaggtgctg gagcagttga tgaagatgat tttataaaag cttttacaga     1140

tgtcccttct attcagattt attctagtcg agaactcgaa gaaacattaa ataaaatcag     1200

ggaaattttg tcagatgata aacatgactg ggatcagcgt gccaatgcac tgaagaaaat     1260

tcgatcactg cttgttgctg gagctgcaca gtatgattgc ttttttcaac atttacgatt     1320

gttggatgga gcacttaaac tttcagctaa ggatcttaga tcccaggtgg ttagagaagc     1380

ttgtattact gtagcccacc tttcaacagt tttgggaaac aagtttgatc atggcgctga     1440

agccattgta cctacacttt ttaatctcgt ccccaatagt gcaaaagtca tggcaacttc     1500

tggatgtgca gcaatcagat ttatcattcg gcatactcat gtacccagac ttataccttt     1560

aataacaagc aattgcacat caaaatcagt tcccgtgagg agacgttcat ttgaattttt     1620

agatttattg ttgcaagagt ggcagactca ttcattggaa agacatgcag ccgtcttggt     1680

tgaaactatt aaaaagggaa ttcatgatgc tgacgctgag gccagagtgg aggcaagaaa     1740

gacatacatg ggtcttagaa accactttcc tggtgaagct gaaacattat ataattccct     1800

tgagccatct tatcagaaga gtcttcaaac ttacttaaag agttctggca gtgtagcatc     1860

tcttccacaa tcagacaggt cctcatccag ctcacaggaa agtctcaatc gccctttttc     1920

ttccaaatgg tctacagcaa atccatcaac tgtggctgga agagtatcag caggcagcag     1980

caaagccagt tcccttccag gaagcctgca gcgttcacga agtgacattg atgtgaatgc     2040

tgctgcaggt gccaaggcac atcatgctgc tggacagtct gtgcgaagcg ggcgcttagg     2100

tgcaggtgcc ctgaatgcag gttcctatgc gtcactagag gatacttctg acaagctgga     2160

tggaacagca tctgaagatg gccgggtgag agcaaaactt tcagcaccac ttgctggcat     2220

gggaaatgcc aaggcagatt ctagaggaag aagtcgaaca aaaatggtgt ctcaatcaca     2280

gcctggtagc cggtctgggt ctccaggaag agttctgacc acaacagccc tgtccactgt     2340

gagctctggt gttcaaagag tcctggtcaa ttcagcctca gcacaaaaaa gaagcaagat     2400

accacggagc cagggctgta gcagagaggc tagtccatct aggctttcag tggcccgaag     2460

cagtcgtatt cctcgaccaa gtgtgagtca aggatgcagc cgggaagcta gtcgggagag     2520

cagcagagac acaagtcctg ttcgctcttt tcagcccctc ggtccaggtt atgggatcag     2580

ccaatcaagt cgactgtcgt cttctgttag tgccatgcga gtcctgaaca caggttctga     2640

tgtggaggag gcggtggcag atgccttgct cttaggagac atacggacta agaaaaaacc     2700

agctcgaaga agatatgaat catatggaat gcattcagat gatgacgcca acagcgatgc     2760

atctagtgct tgttcagaac gctcctatag ttctcgaaat ggtagtattc ctacatatat     2820

gaggcagacg gaagatgtgg cagaagtcct caatagatgt gctagttcca attggtcaga     2880

aaggaaagaa ggcctcctag gtctgcagaa cttattaaaa aatcagagaa cactaagtcg     2940

agttgaactg aaaagattat gtgaaatttt cacaagaatg tttgctgacc ctcatggcaa     3000

gagagtattc agcatgtttt tggagactct agtggatttc atacaagtcc acaaagatga     3060

tcttcaagat tggttgtttg tactgctgac acaactacta aaaaaaatgg gtgctgattt     3120

gcttggatct gttcaggcaa aagttcagaa agcccttgat gttacaagag agtcttttcc     3180

aaatgatctt cagttcaata ttctaatgag atttacagtt gatcagaccc agacaccaag     3240

cttaaaggtg aaggttgcta tccttaaata catagaaact ctggccaaac agatggatcc     3300

aggagatttt ataaattcca gtgaaactcg cctagcagtg tctcgggtca tcacttggac     3360

aacagaaccc aaaagttctg atgttcggaa ggcagcacag tcagtgctga tttcattatt     3420

tgaactcaat accccagagt ttacaatgtt attaggagct ttaccaaaaa cttttcagga     3480

tggtgctacc aagcttcttc ataatcacct tcgaaacact ggcaatggaa cccagagttc     3540

catggggagt cctttgacaa gaccaacacc acgatcacca gctaactggt ccagtcctct     3600

tacttctcct accaatacat cacagaatac tttatctcca agtgcatttg attatgacac     3660

agaaaatatg aactctgaag atatttatag ctctcttaga ggtgtcactg aagcaatcca     3720

gaatttcagc ttccgtagcc aagaagatat gaatgagcca ttgaaaaggg attctaaaaa     3780

agatgatggc gattcaatgt gtggtggtcc tgggatgtct gacccaagag caggaggtga     3840

tgctactgac tcaagtcaaa cagctcttga taataaagct tcattgctcc attcaatgcc     3900

tactcactcc tctccacgct ctcgagacta taatccatat aactattcag atagcatcag     3960

tcccttcaac aagtctgccc tcaaggaagc catgtttgat gatgatgctg accagtttcc     4020

tgacgatctt tccctagatc attctgacct agttgcagag ttgttgaagg agctgtctaa     4080

ccataatgag cgtgtagaag aaagaaaaat tgccctctat gaacttatga aactgacaca     4140

ggaagaatct tttagtgttt gggatgaaca cttcaaaaca atattgcttt tattgcttga     4200

aacgcttgga gataaagagc ctacaatcag ggctttggca ttaaaggttt taagagaaat     4260

cctaaggcat caaccagcaa gatttaaaaa ctatgcagaa ttgactgtca tgaaaacatt     4320

ggaagcacat aaagatcctc ataaggaggt ggtgagatct gctgaggaag cggcatcagt     4380

gttggccact tcaattagtc cagagcagtg catcaaagtg ctttgtccta tcattcaaac     4440

tgcagactac ccaattaatc tggctgcaat caaaatgcaa acaaaagtga tagagagagt     4500

gtccaaggaa accctaaacc tgcttttgcc agagattatg ccaggtctaa tacagggtta     4560

tgataattca gagagcagtg ttcggaaagc ttgtgtcttc tgcctggtgg ctgttcatgc     4620

ggtaattggt gatgaactaa aaccacatct cagtcaactt actggcagta aaatgaagct     4680

actgaatctt tacatcaaac gtgcacaaac aggttctgga ggagctgatc ccactactga     4740

tgtttctgga caaagttagt gaagctcatc acagcgaacc aggtctctca aaagaaagga     4800

cagatagacc accctcatca atgaaaggaa gttctcaaac acatcctttg gaacttacta     4860

ttgtttccca gttttagttt tttgtttcgt ttcgttttgt attttctgta acagaggact     4920

atcctcagtc tgcatgtaac ttttatgata gttattccaa attcaagaag aagcagtatt     4980

aacatcaatt gatcgacaca aagtaatttt taatttaatt catcatttca catgtttgta     5040

ctttgtcttc ccattaacct ttgccagtgt tatgattgta taaatttttt taaatgctgg     5100

ttaaacagga atgcttaaag ctttaaaagt ttaacagtct aaaacatttt tgcttttatt     5160

caactgcaga ataatatttt tattgctact ttgagttttg tttcgtatca tgtcctatgc     5220

tagaaatatt taaatgatgt gaaacaaagc aggactaatt tgaactacag ctggactccg     5280

tttgtgtgat ggtgatacat gtcattagtt gcaacttctt tggggtgatc tatagtttga     5340

aaactaaaac ctcaaagaca gatgttacag aatcagccag ttctgtaaaa ctgatattgt     5400

ctattggtta ttgatcttgc catctttatt taaaaccatg tcccttctat gatcccttaa     5460

gaaagctgca ccaaatcatc tgcctgtttt ttcttgatac ttactgaaat agaaggtttt     5520

attgcagggt ttattttggt ttgtttatat ctttgttgtg aatgatgctt ttttgtattt     5580

attaatatca aattcactta tgaataaact tgataatgga aacggacaaa aaaaatcaag     5640

tgcgtgtgtg tccttgaccg tcttctgttt ctcacgtaat aaacaaatta tcgagacatg     5700

ggagtgacca gcaccttttc tttaaatggt ggaacctggt ttccttttac catgaaattg     5760

tcttacttga aaatattgat cctgatgaga gagaagatgg tgccaaggct gtctttgtat     5820

aatgggctca aattctctac ctcttcaggg ctaatacttt taactgagct gctgcctata     5880

gtgtcttttg gaaaactact taaagggtga ttttctgtta ctttttagca aattttttta     5940

atcacctctt gctacaccca ttcttttcat gtgcagccga ctcaaaaatt accagttttg     6000

gtgaaaggct aaattagata atttggaacc aggatactaa tgatttctca tctttacttt     6060

tttttaatcc taatataaag tgaatttgat tgaaaaggca aatagctatt agggaagcag     6120

tttgccattg ttgcagagtt atctgtactt tgtttaactg aaaaaaatgt agaaatatat     6180

gtaaagaatt taagacaaga gtactgaatg gatgatttgt cataggcttt cccctttctt     6240

tctgttctag cagcaggaaa agtttctcta tatcctctcc ctctacctgt aacaattttg     6300

ttttctactg ttaattacat tgtgtattta tagttctatg cttactgttg tgcatatact     6360

ggcaataaaa ctgtacataa cattacttga aaaagttaat aatgtatatc agtttttctg     6420

tctcactgtg taacaagtca ctcagtttta ttttaacttt agacggtctt gtatcagtgg     6480

tggtctcttg aattttgtaa gttcatctga ggagaaaaga tttttcaggt gtagctacca     6540

caatcaaagg tatatagcta catacgcatg tatatattac agcttatctg taagaagaaa     6600

atgcatttta aacacaactc ttctcagtag cattttatga cctttggata tgtttgtaat     6660

catttcgaat caaaatattg atttaatttt gacctctggt ttaagatact gctttaacta     6720

ctgttgacaa ccaagtagag tgacttaagc tgaacagtaa ctaactggaa aattagataa     6780

gcacctggca tctaatggca ggcaggcact caagaaatga attaactaca taatggaaaa     6840

gtatggttta atgtgtccaa atgaaagcta gtagatgtaa acatggaaaa attgtgttta     6900

caattttata atctcagttg ataagactat aagaaagctg attatttaaa tcactatata     6960

caatacaccc ttaatttgtt cattccagaa acatactgag atgtcagcta cttaaaaatg     7020

gtcacaaaaa gctactgttt atatttttcc tcctgctatt ctctcccaaa ttaattatta     7080

ataagtgttg ttcatttact gcactgctga gaactaatta aaattatata ttccagattg     7140

taaaaaaaaa aaaaa                                                      7155


<210>  1893
<211>  10472
<212>  DNA
<213>  homo sapiens

<400>  1893
gctgacgacg catgcgccgg gagggggcgc aatcacggac tcggcttgcg gctgccggtt       60

taaaaaagga aaccccggag agcgagagcg cgaaggaaat ctggccgccg ccgccgcgag      120

cgctcccgaa tttttacttg ttcctgcaaa gctgctggag ctcagaagct gattctatca      180

cattgtaaga tgcctttgga taattctaca gtcctcttaa atgaatcttt agaacttggc      240

aagtctcact agataccttc aatcatcatt ttgagctcaa agaattctga gacttatggt      300

tggtcatata gaagagtacc ttgaacctat agtttcctga agaatcagtt taaaagatcc      360

aaggagtaca aaaggagaag tacaaatgtc tactacaaga cgaaaacgta gtatgttatg      420

ttgtttaccg taagctgtag taaaatgagc tcgattgttg acagagatga cagtagtatt      480

tttgatgggt tggtggaaga agatgacaag gacaaagcga aaagagtatc tagaaacaaa      540

tctgaaaaga aacgtagaga tcaatttaat gttctcatta aagaactggg atccatgctt      600

cctggtaatg ctagaaagat ggacaaatct actgttctgc agaaaagcat tgatttttta      660

cgaaaacata aagaaatcac tgcacagtca gatgctagtg aaattcgaca ggactggaaa      720

cctacattcc ttagtaatga agagtttaca caattaatgt tagaggctct tgatggtttt      780

tttttagcaa tcatgacaga tggaagcata atatatgtgt ctgagagtgt aacttcatta      840

cttgaacatt taccatctga tcttgtggat caaagtatat ttaattttat cccagaaggg      900

gaacattcag aggtttataa aatactctct actcatctgc tggaaagtga ttcattaacc      960

ccagaatatt taaaatcaaa aaatcagtta gaattctgtt gtcacatgct gcgaggaaca     1020

atagacccaa aggagccatc tacctatgaa tatgtaaaat ttataggaaa tttcaaatct     1080

ttaaacagtg tatcctcttc agcacacaat ggttttgaag gaactataca acgcacacat     1140

aggccatctt atgaagatag agtttgtttt gtagctactg tcaggttagc tacacctcag     1200

ttcatcaagg aaatgtgcac tgttgaagaa cccaatgaag agtttacatc tagacatagt     1260

ttagaatgga agtttctgtt tctagatcac agggcaccac ccataatagg gtatttgcca     1320

tttgaagttc tgggaacatc aggctatgat tactatcatg tggatgacct agaaaatttg     1380

gcaaaatgtc atgagcactt aatgcaatat gggaaaggca aatcatgtta ttataggttc     1440

ctgactaagg ggcaacagtg gatttggctt cagactcatt attatatcac ttaccatcag     1500

tggaattcaa ggccagagtt tattgtttgt actcacactg tagtaagtta tgcagaagtt     1560

agggctgaaa gacgacgaga acttggcatt gaagagtctc ttcctgagac agctgctgac     1620

aaaagccaag attctgggtc agataatcgt ataaacacag tcagtctcaa ggaagcattg     1680

gaaaggtttg atcacagccc aaccccttct gcctcttctc ggagttcaag aaaatcatct     1740

cacacggccg tctcagaccc ttcctcaaca ccaaccaaga tcccgacgga tacgagcact     1800

ccacccaggc agcatttacc agctcatgag aagatggtgc aaagaaggtc atcatttagt     1860

agtcagtcca taaattccca gtctgttggt tcatcattaa cacagccagt gatgtctcaa     1920

gctacaaatt taccaattcc acaaggcatg tcccagtttc agttttcagc tcaattagga     1980

gccatgcaac atctgaaaga ccaattggaa caacggacac gcatgataga agcaaatatt     2040

catcggcaac aagaagaact aagaaaaatt caagaacaac ttcagatggt ccatggtcag     2100

gggctgcaga tgtttttgca acaatcaaat cctgggttga attttggttc cgttcaactt     2160

tcttctggaa attcatctaa tatccagcaa cttgcaccta taaatatgca aggccaagtt     2220

gttcctacta accagattca aagtggaatg aatactggac acattggcac aactcagcac     2280

atgatacaac aacagacttt acagagtaca tcaactcaga gtcaacaaaa tgtactgagt     2340

gggcacagtc agcaaacatc tctacccagt cagacacaga gcactcttac agccccactg     2400

tataacacta tggtgatttc tcagcctgca gccggaagca tggtccagat tccatctagt     2460

atgccacaaa acagcaccca gagtgctgca gtaactacat tcactcagga caggcagata     2520

agattttctc aaggtcaaca acttgtgacc aaattagtga ctgctcctgt agcttgtggg     2580

gcagtcatgg tacctagtac tatgcttatg ggccaggtgg tgactgcata tcctactttt     2640

gctacacaac agcaacagtc acagacattg tcagtaacgc agcagcagca gcagcagagc     2700

tcccaggagc agcagctcac ttcagttcag caaccatctc aggctcagct gacccagcca     2760

ccgcaacaat ttttacagac ttctaggttg ctccatggga atccctcaac tcaactcatt     2820

ctctctgctg catttcctct acaacagagc accttccctc agtcacatca ccagcaacat     2880

cagtctcagc aacagcagca actcagccgg cacaggactg acagcttgcc cgacccttcc     2940

aaggttcaac cacagtagca cacgtgcttc ctctcttgac atcaagggag gaaggggatg     3000

gcccattaag agttactcag atgacctgag gaaaggaggg aaagttccag cagtttcatg     3060

agatgcagta ttgagtgttc tagttcctgg aattagttgg cagagaaaat gctgcctagt     3120

gctacagatg tacattaaat accagccagc aggaggtgat cataggggca tagccagttc     3180

tgacagtgtt ttaggtgcct ggatattttt tgatggaaaa agaatatatt gccaaatatt     3240

aagaagctca gctatgaaat gacctccagg gaatcagaaa ggcactaatg atgttagtaa     3300

cttttagtgg ttctgtgcct cttatcaagt gttacagagg acataccact gccatgtcag     3360

gggtttgctt acagtgatgc catgaagaca gtccagtaga cttggtagcg accccctccc     3420

ccaacccctc tcccttttca gataatgatg gaacagtaat tactttcaga atgttgtgtg     3480

ggttcaaatt ctctatgtac agatgatgta aaaatatgta tatgtctaga taaaaggaga     3540

gaaagcaaaa cattttgtat gctgcatgaa agcgttatct cttccttaca ggtgtgagca     3600

cctttcctga aattctgaca ccatgtgcaa actgatccat cctgtttttc cttttgttta     3660

caacacagta gtgttctgtt cacttttccg gggcacaagt ttttttgttc atactttggc     3720

tgtgatgtca cagtttgttc agtgaggtat gatgtgctgc tgggaatgga tttttttttt     3780

caggttaaat tattgataca acaggatttt caagttattc agaaatatcc ctcatttcat     3840

tatttttcaa ttatgtttga aaataggatt tgcactgctt tattttaggt ggctgggagt     3900

tttgattgca tattttgtta tagttcatag ttggaaatat ttgcgtaaat ggttttcaac     3960

aagcctgaaa gtaatttcaa gaatgtttca gttatagagg taaaatttgc acacaaaaca     4020

tcttaggcac tttttaacat tctcaatcat gggaatttta acttttggga tttgttgaaa     4080

tcttttttat tatccttcac aatttcaatg cttcttttag tcagaaatga ttcagggtta     4140

tttgagggga aaaaacccca tagtgccttg attttaattc aggtgataac tcaccatctt     4200

gaagtcattg tccggtttcc gtagcagttt tgaaacctta gtaccttttt aacagcatgt     4260

gggtgtcagt gtcattatta gtctcctaat aagttcctct gaagactgct atcagtctct     4320

tggactggag gtacaaataa tttagaaata aaagatgata acctaacact atcatagtta     4380

ttaatgtgat cctaaaattg tttcctaaat cagcattttt ctttagtcat ttaagaattt     4440

accagaaata tttgctcaat atgatcttga tattcctaca aagaaaaaag aaggggtagg     4500

gatttggcta tgccttcact acaacattag aatattgtaa ctcacatgcc ttctaaacgt     4560

gaactaagat ttcctttggc aatatcatat tctaaaagta ataaattcca atacaagtta     4620

catacattta aaaaacattt tacagatttt atggtactaa tgaaatttac agtgatagaa     4680

caaaagagga ttagtagaaa atacattatt agaatataaa aaatgttatt actgaggaaa     4740

gggaggagag gacaagtgta ataaatcaaa attgacctca aaagaaaatg tgtaacagag     4800

ttgaggttgt taaaacagaa aaggttctga ataatgaaga ttaacctaat gcagaattgc     4860

taggtaaaga ggtcagggga atgctaagcc agttcttaag acttctctgt cctctgcttt     4920

gctgttatcc ttaaggcata tactttgtct ttctgcagaa aattctacct ggctacaatt     4980

actttgaaca ttaatgttga aaaagaaaac aaccaaagaa aattggtact tacccttcta     5040

caaaagaagt gtgactagat atcaatcagt aattaacata tcaaggagct cttctagcta     5100

aatgaccatc cagtagagat ttcccacatt cccatgaata tcaagaatag ttgtcagaat     5160

atgtatgtac ctgagcatat gtacacagac aagggggatg ttgtggaata tggcaatagc     5220

attgttcttc tcccctttca aattgccttt cttgacctta tgccattcca tatatatctg     5280

agttgtgcct catttattta ttggcaatac ctagtgatac ggatttagct aacaaaagat     5340

atgaagaact attatattga ggcctgtcct ctacatacca cacttaaaag atggtgaact     5400

gtgagtacta cttaggttga cagcaacaaa gcataagaca agccccaggt aaacgtctaa     5460

actgtttact cacattgtcc tactccagcc ccttcaatta tttcccatct ccacaaatag     5520

tcgggggaaa aaattaaaat tttcctttat gattcttact gttcttcgca gctcatcttt     5580

tcctgcttag aattaaccat tgctaattta aaggagcagc tagctgcttt tctgtcagtc     5640

tgaagcgtag tagtggaaga ggtagtaagc accagctgcc tctttgctgc tttgttttcc     5700

tcctgattct cttaaatttg ggttgcaaag ctatcccgcc ccccaccctg ccccatgaaa     5760

cttgagcatt caaatgaaga ttcagcagtg tctgttcttc atttctatag ccaaagctgt     5820

tagttaaaat cccaaatcta tagcatttaa agataccaaa tagaaacacc ttccagcttt     5880

aaaaaaaaaa aaaaaaaagt cttccctctg ctttattctc actttcttaa aaacacttat     5940

tctgggtggt actttttagg taagaaacta ctgagtttca ggaaaaatgc tagctactct     6000

gcagttaccg tgctttggac ttgcagttat catagttttg ggagagtcag tattgtttaa     6060

caaatgcaag tgagaactag aagggttaat aaagttgctc cttagagtgg tgtcaaacca     6120

gaaccgagac acttaaaaag tacttcattt tttgaatgga aaatattgga gaaaagtatg     6180

ggagatgcag gtagcatgtg agtaaatact acggtctagc cttcgagcat cccaaattcc     6240

gggggtaact tgacagtgct gtgctctcct ttgtcattta tatctggctt aggaatggaa     6300

tagtaataac aagatgccag tgatttggaa tagtttgtta tagaacattc agtgcaaaat     6360

agtgaaaatg tttggtcttc agaagtgctg tagttgttgg tcattgcctt aaagcagtct     6420

gcttgacgct aggagcactg aagcagtcca gctccatcaa gagcactgtt gaagggagaa     6480

gaacccttgt tcaggaagcc ttagaaaggg atccttaaaa tagtactcta cgcagacaag     6540

tgaaaattct tttaaactgg atattactca acatgttttc agatgtttcc actacattga     6600

ggcaaacttt ttaaaagtgg aatgcaaata gcattttact ttagtatttc tgcttttttc     6660

tttctgtttc tttggtaatt gaaagtttgt tgatgaatat ttgtgtaaaa cgcattcaag     6720

tctataacct ttccaattac ctgtggccct tagtcccaca ggagtccctg ttggaagggg     6780

gtaaacactg gatattaatg ttgctgagtg agtctttcta gccaggacaa gctgattgga     6840

atttttgaat ggtagagaag aaacagcaca aaggcacttg ccattttaag tgtttggaga     6900

aagagaacct tttaagtttg gattgggtga gctttcttct aaaaggagct tctgaagtaa     6960

ttgcaaagga atagaatcga ctatttttat agtatattta atatatttgt atataactat     7020

aataggaacc ctctacatgc ctcccacttt tctaatttac ttcccctttt gccatagcac     7080

tagtatagcc tcatccgcat gggtaatgtg cctattgtca gcctaccaaa agatagtgct     7140

gctgctttat gagacaggtg agaagaccca actctcatgc ctggggatcc tttacggaag     7200

gaatagcaca cacttttaaa acaacatacc acagtctaaa agcatcattt tgaaatgtaa     7260

caagcacttt attgcaatta ctcattttga taaagtttat tcttaggcgt taaccatttc     7320

taaaggatcc ccaaatcatc acttacttag gtgaaattat ataaaatgac acatttctga     7380

gaaatgttta ggtccagtga accgtagttg gtttatggga gtgatttcaa gatagccaaa     7440

tgaactttga tttttgtttt gaatgtggtg gagtcaagag attgtagatg cctagtttga     7500

tttaaacact attgtaaacc tatcttgcct attgtgtgga caccaaaaga gaccaatgag     7560

cctgtttatt tttcagaggt ctaggaaaat tgcatccgtg tgagtagatg tacagaacta     7620

atctaaaagt gattgctagt aacattttag aatataataa tttcaagaat tattctgagt     7680

gttttaaatg tgccctgaaa tgttggcatg tcatttcagc atttccattt gaattgctct     7740

tgtaatattt ttgcacaaaa aggactgaga aaaagaatac tttggttaaa ggaaaaaaat     7800

agtataattt ggtctttaat tttaatgtct cctgtggaaa cactggggat gaattttgtt     7860

ggcacagtta ttcaggatat ttaaaacagt gttgaacagt tcacaagaaa ttaagcaaac     7920

ttggatttta aaaattaaaa tactttcttt ccatgtgact gttttgcata gttttttccc     7980

cctatgtcat aacactacat tccttgtttt tcttaaataa aatactctgc aggttttgtt     8040

gtgagtgttt ataacagtat tttgtaagct gcctgggttt cctcagggaa acattattta     8100

gtggaatagg atatagttta tggagagaca actaagtgaa attccatcac caccaccagc     8160

aaacactgag gtgctgcatt aagtgacaat caaactagta agtatttatg aaagaattta     8220

gaaaggggtt caaagaagca attgctttta aagcagttct ctggggttct tgaataaaaa     8280

tggctaaatg tatttattta tattttaaaa tacctgtgtg ttctgttttc tcatcaaagt     8340

gatttcggtg tcatgtattt aatgtgtggt ttgttttgtt ttgcaccata ttcttcttag     8400

ggaactggct ctgatttggg gtgcagtcac caactctcat gataatcttt acggacagtc     8460

tgaatctact ttacttcagg acggcagtgg aggggccaac tccagatgcc cctgcacttc     8520

cctcctcaag tcatctaaga aagaatttta gaaataactc ctttcaaatc tgattcatac     8580

agttccaacc tttttctagt ttcacttgct gccttctttg ttttatgggc actttttgtg     8640

tgattacttc cccaacacag tcaaaggcca gtatgacaga accaatggca catgatgcct     8700

ctattttgcc catttgggga aatgttagta aaagaaatag catcttttaa tggctgtcat     8760

tatcatatcc atattaaaat ccatttaaag ttcttaaatt tggcggaata atgtatacag     8820

gctgtaaact tctacaaaaa atgtttgctg tctttaatat ggtgtcaagt tacttggtcc     8880

tttgaaaaca aaacaaaact tccatacaca gcactgccca gtaaagcagt gttggaatat     8940

tggaaaccta gacatttgag gatccttctt gctcacaagc attggaacag aatcctccac     9000

tttaggactc agagaagcta tggagtccca caggctaggt atagcacaca acttagagaa     9060

cggtagttaa agcacgtcaa ccacaattga atttaatgat ctaaaaaata tttcttaact     9120

ctgagggtta aactgaagat acgttttcaa ataaaagctt ttaaatttct taggaaacaa     9180

actgtgacat cgcttttaaa aatgacattc aaatgtttat aatgtgtgtt tttgagttgg     9240

cttggactag tgcaagttca ctgctggcaa tggttatgcc agtagttaag ttaaaataag     9300

ttgttacctt cagattgatg tcttgtataa ccagacaatc atcttcaagc aaaaaaattg     9360

gccaggaaat gtctttttaa aaaaaaaaaa aaaaaaaaag atgtgtcagc cagaacagtt     9420

accattcaga ccatactgga atgattttga aatctttact atggtttaag ttggggaagg     9480

cctcagtatg gcattttcat attcactcta tgtaaagatt gaagcccaaa gatgagttaa     9540

attcagtgct gtattgaaac cagtcagtgc aaaaaaaaaa aaaaagtttt acctttgtaa     9600

atttttcatt gttaacatca gttggtagtt gttaaaacat gcaccaaatt ctttataatg     9660

ttctgtgtgg ttctcaatgt gatattcttg acattgctgt ccttactgct tggttcttgg     9720

ttttaaatta aaaagtagat gtagctcatc atttttactt ccaaaacggt ggagctaaaa     9780

acggctaatt gatcttgaga taagaatacc ctttactaag gcaaagattt aattgaaatc     9840

caaaatgatt tatagaaacg aaaggcattt tccatttgtt gtcttctgcc gaaattctga     9900

attgcataca cacatgaagg ataatgaatg gtttcaacgg tgctatatta ggttctctga     9960

ttttcatgac ctatgtatgt ttggaaatac aatattgtat aaaatgtgga tcgttttgtt    10020

accgatttaa tattgccatt ttaatttggt gtaacaattg gttacacttg tttttcaaag    10080

ctatcctttg aggagaaagt caaaatgtgt tgttagccta cctccactca ggcctcttgc    10140

tgtgtaatca ttattccagg ttatgatgtg catagctttt aaaactgcgt gtactattat    10200

tctgctcttt cccatactct tgtcatgtat tcagaaccta aacttatagc aaaagagcca    10260

agcagtagca gtttttgtaa atgtaaaaat aattagatcc agactttgtt tccttcaatt    10320

ttaaaaataa aaaatacctc agtgctatgt ttttcagtta tcacctgcat ttctcaaaaa    10380

ataacacctg cttcatgtgg cacataactt gtaagaatca cattttggat tttaaagaaa    10440

gactattaaa tattttaaga tcactatcaa tg                                  10472


<210>  1894
<211>  2548
<212>  DNA
<213>  homo sapiens

<400>  1894
gtcgcgccga gggtgacgcg tggcgtagac gacgccgtcg gcctgcgcct gtcacccccc       60

tcctcccggg gtttgtagcg gaggaggagc gggcgccatg gcggttctac tggagaccac      120

tttaggcgac gtcgtcatcg acttgtacac cgaagaacgg ccgcgtgcct gcttgaattt      180

cttgaaactg tgcaaaataa aatattacaa ttattgcctt attcacaatg tacagaggga      240

ttttatcata caaactggcg atcctacagg gactggccgt ggaggagagt ctatctttgg      300

ccaactgtat ggtgatcaag caagcttttt tgaggcagaa aaagtcccaa gaattaagca      360

caagaagaaa ggcacagtgt ccatggtgaa taatggcagt gatcaacatg gatctcagtt      420

tcttatcacc acaggagaaa atctagatta tcttgatggt gtccatacgg tgtttggtga      480

ggtgacagaa ggcatggaca taattaagaa aattaatgag acctttgttg acaaggactt      540

tgtaccatat caggatatca ggataaatca tacggtgatt ttagatgatc catttgatga      600

ccctcctgat ttattaatcc ctgatcgatc accagaacct acaagggaac aattagatag      660

tggtcgaata ggagcagatg aagaaattga tgatttcaaa ggaagatcag ctgaggaagt      720

agaagaaata aaggcagaaa aagaggctaa aactcaggct atacttttgg agatggtggg      780

agacctacct gatgcagata ttaaacctcc agaaaatgta ctgtttgtgt gtaaattgaa      840

cccagtgacc acagatgagg atctggaaat aatattctct agatttgggc caataagaag      900

ttgtgaagtt atccgagact ggaagacagg agagtccctc tgttacgctt ttattgaatt      960

tgaaaaggaa gaagattgtg agaaagcatt cttcaaaatg gacaatgtgc ttatagatga     1020

cagaagaata catgtggatt ttagccagtc ggttgcaaag gttaaatgga aaggaaaagg     1080

tgggaaatac accaagagtg atttcaagga gtatgaaaaa gaacaggata aaccacctaa     1140

tttggttctg aaagataaag taaagcccaa acaggataca aaatacgatc ttatattaga     1200

tgagcaggcc gaagactcaa aatcaagtca ctcacacaca agtaaaaaac acaagaagaa     1260

aacccatcac tgttctgaag agaaagaaga tgaggactac atgccaatca aaaatactaa     1320

tcaggatatc tatagagaaa tggggtttgg tcactatgaa gaagaagaaa gctgttggga     1380

gaaacaaaag agtgaaaaga gagaccgaac tcagaaccga agtcgtagcc gatctcgaga     1440

gagggatggc cattatagta atagtcataa atcaaaatac caaacagatc tttatgaaag     1500

agaaaggagt aaaaagagag accgaagcag aagtccaaag aagtccaaag ataaagaaaa     1560

atctaagtat agatgaaaga tgaagaggca gaattgagag gctaacatat ttactcttgt     1620

ctaacttaag agtgccagga aagcagatgc ttagattttg tgtcaaagct tgttattttt     1680

ttcatactag gattatggtc tttagattaa tactgattat atagagcacg gaaagataaa     1740

gaattgaaca ttttctttgt atactttttt acactaattt tattgttata cataaatggt     1800

agtcttcatt tttgaagtct tacattttca ctcttttttt aatgaagtat ttcatactac     1860

aaaaatacat aaacgtatat ataaagggat aataaatgta aatatctgtg tactcatcag     1920

ccagcttaag atacagatgt tgtcgacatt ttagaagttc cctaaggccc tctccctctc     1980

aaataattat ttggaatttt gtgtttgtca tttgtctatt atagttttac aacatacgta     2040

tgtatctgta agtgaaatgt taattttgta tgtttctgaa ttttatataa atggcaaaat     2100

gtttacttct gtgactttct ttcattttta ttgctatata gtattatata aatatactac     2160

aacttattca ttcttgatgg acatttgagt tttgtttatt tgtttttgct gttgaaacaa     2220

tgctgctgtg aacattgtat ctagcagtta tattgcttga tatattgata aaataatgcc     2280

aaatttgtgt tctgaagtga ctgtactagt ttatacctct cttggcactg tgagttacct     2340

ttgtttcata gcatctccaa cacttaagtt cagacttaaa aatttgccaa cctagtggat     2400

gttaagtggt atctacctgt gatttccagc aagattactg ttatctctgc tcttccatgt     2460

gtaagatgtc atttttttcc tggctgcttt taaggttttc tgtcactggt tgtaagaagt     2520

ttgattatga tgtgaaaaaa aaaaaaaa                                        2548


<210>  1895
<211>  1085
<212>  DNA
<213>  homo sapiens

<400>  1895
cgtgtgtatg tgtatttggg gggactgaag ggtacgtggg gcgaaacaaa accggccatg       60

gcagcagcgg aggaggagga cgggggcccc gaggggccaa atcgcgagcg gggcggggcg      120

ggcgcgacct tcgaatgtaa tatatgtttg gagactgctc gggaagctgt ggtcagtgtg      180

tgtggccacc tgtactgttg gccatgtctt catcagtggc tggcacggcc agaacggcaa      240

gagtgtccag tatgtaaagc tgggatcagc agagagaagg ttgtcccgct ttatgggcga      300

gggagccaga agccccagga tcccagattg aaaactccac cccgccccca gggccagaga      360

ccagctccag agagcagagg gggattccag ccatttggtg ataccggggg cttccacttc      420

tcatttggtg ttggtgcttt tccctttggc tttttcacca tcgtcttcaa tgcccatgag      480

cctttccgcc ggggtacagg tgtggatctg ggacagggtc acccggcctc cagctgacag      540

gattccctct tcctgtttct cgccatcttc ttcttttttt ggctgctcag tatttgagct      600

atgtctgctt cccgcccacc tccagccaga ggagaatcag tattgagggt ccctgctgac      660

ccttccgtac tcctggaccc ccttgacccc tctatttctg ttggctaagg ccagccttgg      720

acattctcca ggaaggcctg gggaggagga gtgaagtctg tgcatagatg ggagagcctt      780

ctgctcagag gctcactcag taacgttgtt taattctctg ccctggggaa ggaggatgga      840

ttgagagaat gtctttctcc tctcctaagt ctttgctttc cctgatttct tgatttgatc      900

ttgaaaggtg ggcaaagttc cctctgactc ttcccccact ccccatctta ttgatttaat      960

ttaatttttc actccccaga gtctaatatg gattctgact cttaagtgct tcctccccct     1020

cactacctcc tttaatacaa attcaataaa aaaggtgaaa taaaaaaaaa atcaataaag     1080

caaaa                                                                 1085


<210>  1896
<211>  2484
<212>  DNA
<213>  homo sapiens

<400>  1896
attcctcgtt agggcaggcg cggccccttc ggctccgagc tgaccctgat cagggccgag       60

ttgtctcggc ggcgctgccg aggcctccac ccaggacagt ccccctcccc gggcctctct      120

cctcttgcct acgagtcccc tctcctcgta ggcctctcgg atctgatatc gtggggtgag      180

gtgagcaggc ccggggaggg tggttaccgc tgaggagctg cagtctctgt caagatgata      240

gaggtactga caacaactga ctctcagaaa ctgctacacc agctgaatgc cctgttggaa      300

caggagtcta gatgtcagcc aaaggtctgt ggtttgagac taattgagtc tgcacacgat      360

aatggcctca gaatgactgc aagactaagg gactttgaag taaaagatct tcttagtcta      420

actcagttct ttggctttga cacagagaca ttttctctag ctgtgaattt actggacaga      480

ttcctgtcta aaatgaaggt acagcccaag caccttgggt gtgttggact gagctgcttt      540

tatttggctg taaaatcaat agaagaggaa aggaatgtcc cattggcaac tgacttgatc      600

cgaataagtc aatataggtt tacggtttca gacttgatga gaatggaaaa gattgtattg      660

gagaaggtgt gttggaaagt caaagctact actgcctttc aatttctgca actgtattat      720

tcactccttc aagagaactt gccacttgaa aggagaaata gcattaattt tgaaagacta      780

gaagctcaac tgaaggcatg tcattgcagg atcatatttt ctaaagcaaa gccttctgtg      840

ttggcattgt ctatcattgc attagagatc caagcacaga agtgtgtaga gttaacagaa      900

ggaatagaat gtcttcagaa acattccaag ataaatggca gagatctgac cttctggcaa      960

gagcttgtat ccaaatgttt aactgaatat tcatcaaata agtgttccaa accaaatgtt     1020

cagaagttga aatggattgt ttctgggcgt actgcacggc aattgaagca tagctactac     1080

agaataactc accttccaac aattcctgaa atggtccctt aactggatta ttacagcacc     1140

aaaaaacttc tctgaagcct ttctccacaa ccttgttcta tggattccat aatgttacaa     1200

tggatttaag ctatgaagcc tcaaaacatc acgagataag catgatggtc tcagacttgg     1260

gaaaactgcc taatattatg ctgtagtgga attatgttta gatttgaatt catctgtgaa     1320

gcattcaaat caaagctaaa agcctaaatg tgaaatgcta atgacaagcc tgagaaggta     1380

aactgtgaat cttcatttct atcattgatc taactttaga tattggatca atatatttag     1440

gtggtattga aaatgctatt ggaggagtca cactaatact atcaactatc agtcttccca     1500

cagcttcaat cactgtcatt attctaatcc tactcctact taaattttaa gttatgaggt     1560

ttatgtcaaa agcaacattt cacaaatgta cttttaaggc ataataaggg ttaacattct     1620

aggcagtata aacacacccc ataatgcaag taataggtaa tctagagatg tggactttat     1680

tgctatatgg gaattacatt taaatttgag ggcattttat ataaagaaaa atacagacct     1740

ataaagtttg gcatattcat taagttatct tttaatattt ttttctagaa aacaggtgac     1800

atttgtatct acgataaaaa tttttataca gaacctactg cctcaaactg aatcccatca     1860

agaaaactag tttctattgt attagtaact caaaataaat tatcacttcg aaaacttgct     1920

ttcccacact aaggtaagtt cagactagat tgaacactcc agaatttttt actacagact     1980

gtttttaagt tagaagtgat ggcaatttta taaatagaga atatacttcc actgatgccc     2040

ttactgtgcc aaaacaaaaa tcttaagaaa agcaagtaga caccttcata actatgaatg     2100

aagctgctga agtagtgttt aggatcctcc atggcagtta gtgaatgtaa gaagtacagt     2160

gttaaagtgt tgtaaacagt tactcagtgc aatgtatagc ctgagtctat ccatgatggc     2220

tatatccaat ttgacatcac gttatggatc agtacacaat gaaaaaccaa agaaccacag     2280

tatatcttat tcttaacttt tgtaaaccat gttttatggg taacttttta gttttcccaa     2340

aaggctgata aatttcaata ttttgaatac atcattgtta attttgagtt ggcagaggta     2400

aactaaccaa ctaccattat gttttagtac taagggatat acctttcaat aaagttaatg     2460

aaattcaaaa aaaaaaaaaa aaaa                                            2484


<210>  1897
<211>  2354
<212>  DNA
<213>  homo sapiens

<400>  1897
atctaatgag gagcgaggtg cggtgccccg aagcgctcgc ttcccgcggt gcgatctagt       60

cctgcagtag gcggcccggg gccacaccgc ggccgcccaa gccagtgcaa ggcccagggg      120

cctgacatcg ctcccagcgc tcgaggaccg aggcctgctg tggaggacac cgtgctccct      180

cgggacctgc tctggattcc ggcccggacg tccccttgga gctctgcatc tccaacctgg      240

aacccaaccc agaagtctca agtttgacgc atcacgtggc gtgcggatcc actgagggtc      300

cacagagagg ggcgcccatc tcctgcgtct cagttatcct ggtaattgtg tatctgccca      360

ttgttcgttg cctcattaac ttggctttct aggtgcaccc accttgccac cagagaagtc      420

caaatcctga cttctctcca aggtgttggg aattctgtgc cctaaagaat tccgactcag      480

atccgaacgg ggatctggtg gaatcgaggg tgaaagacca gagggacaat gttctactat      540

cccaacgtgc ttcagcgcca caccggctgc tttgccacca tctggctggc ggcgactcgc      600

ggcagccggt tggtgaagcg cgaatacctg agggtgaatg tggtgaaaac ctgcgaggaa      660

atcctcaatt acgtgctggt acgagtgcaa cccccgcagc ccggcctgcc gcggccccgc      720

ttctccctct atctctcagc ccaacttcag atcggtgtga tccgcgtcta ttctcaacaa      780

tgccagtacc tcgtggagga catccagcac atcttggagc gcctccaccg tgcccagctg      840

cagatccgaa tagatatgga gactgagcta cccagcctgc tgcttcctaa ccacctggcc      900

atgatggaga ccctagaaga tgctccagat cccttttttg ggatgatgtc tgtggatccc      960

agacttccta gtcctttcga tatccctcag attcgacacc tcttagaggc tgcaatccca     1020

gagagagttg aagagatccc tcctgaagtt cctacagagc ccagggagcc agagaggatt     1080

ccggtcactg tgctgccacc tgaggccatc acgatcctgg aggcagagcc catacggatg     1140

ctggagattg agggtgaacg ggagctccca gaggtcagcc gccgagaact ggacctgctg     1200

atcgcagagg aagaagaagc tatcttgtta gaaatcccgc ggctcccacc tccagctcct     1260

gcagaggtgg aaggaatagg agaggcactg ggtcctgagg agctgaggct gacaggctgg     1320

gaacctgggg ccctactcat ggaggtgacc cccccggagg agctgcgtct gccagcccca     1380

cccagcccag agaggaggcc cccagtcccc ccacctcctc gccgccgccg tcgtcgccgg     1440

ttactgttct gggacaagga gactcagatc tccccggaga aattccagga acaactgcaa     1500

accagagccc actgctggga atgtcctatg gtgcagccgc ccgagaggac catcagaggc     1560

cctgcggagt tgttcagaac cccaactctc tctggctggc taccccctga actactgggt     1620

ctctggaccc attgtgccca gccaccccca aaagccctca ggcgagagct gcctgaggag     1680

gcagccgctg aggaggaaag gagaaagatt gaagttccaa gtgagattga ggtcccgagg     1740

gaggccctgg agcccagtgt tccccttatg gtgtctttag agatctccct agaggcagct     1800

gaagaggaga agtcccgcat cagcctcatc ccaccagaag aacggtgggc ctggcctgag     1860

gtggaggcgc cagaagctcc tgcattgccc gtggtgcctg aactccctga ggtgcccatg     1920

gagatgcctt tggtgctgcc cccagagctc gagctgctct cactggaagc agtgcacagg     1980

gcagtggcac tggagctgca ggctaacagg gagcccgact tcagcagcct ggtgtcacct     2040

ctcagccccc gcaggatggc tgcccgggtc ttctacctgc tcctggtgct ctcagcgcaa     2100

cagattcttc acgtgaaaca agaaaagcca tatggtcgcc tcctgatcca gccggggccc     2160

agattccact gaggttagag tccatttaca aagctgccag gaaaccggcc acttctagta     2220

aaccacgtcg tgcctcactg ggtcctgctt acctcatttc tgaatgtgca tttccagcct     2280

tcttgctctc agagctattg ttcaagcaga aaacaagctg cttttattac agtaaaaaaa     2340

aaaaaaaaaa aaaa                                                       2354


<210>  1898
<211>  5742
<212>  DNA
<213>  homo sapiens

<400>  1898
gttttagcgg ggactacgat ccaggctgga gttgcgctcg gccggtctga gcgctggcgc       60

tgcccggacg ccgcggggtc cccgccagcc cagggcactc ggcgcgggga tctgcgcgcc      120

tcgctctccc ttcccgatgc cgccgcccgg ctgctgatcg ccgcaccacc ttccctcatc      180

ggcttgggtc cgtggaggtc cctgcagagg caggaagcct ccttaggaaa gcagggatgg      240

aggtaaattg tttaacacta aaagacctga tcagccccag gcagcccaga ctagattttg      300

cagttgaaga tggggaaaat gcacaaaagg aaaatatatt tgttgatcga tcaaggatgg      360

ccccgaagac tccaataaaa aatgaaccaa ttgatttatc gaagcaaaaa aaatttactc      420

cagaaagaaa tcccattact ccagttaagt ttgttgacag acagcaagcg gaaccatgga      480

cacccacagc taacctgaag atgctcatta gtgctgccag cccagatata agggaccggg      540

agaagaaaaa gggactattc cgacccattg aaaacaagga cgatgcattt acagattctc      600

tacagcttga tgttgttggg gacagtgctg tggacgaatt tgaaaagcaa aggccaagca      660

gaaaacagaa aagtttagga ctcctgtgcc agaagtttct agctcgctat ccaagttatc      720

ccttgtcaac tgagaaaact accatctccc tagatgaagt tgctgtcagt cttggtgtgg      780

aaaggagacg catctatgac attgtaaatg tgctggagtc gctgcatctg gtcagccggg      840

tggctaagaa tcagtatggc tggcatggac ggcacagcct gccaaaaacc ctgaggaacc      900

tccagagact aggagaggag cagaaatatg aagagcaaat ggcctacctc caacagaaag      960

agctggacct gatagattat aaatttggag aacgtaaaaa agatggtgat ccagattccc     1020

aggaacaaca gttactggat ttctctgaac ccgactgtcc ctcttcatct gcaaacagta     1080

gaaaagacaa gtctctgaga attatgagcc agaagtttgt catgctgttc ctcgtctcca     1140

aaaccaagat tgtcactctg gatgtggctg ccaaaatact gatagaagaa agccaagatg     1200

ccccagacca tagtaaattt aaaacaaagg tacgacgcct ctatgacata gccaatgttc     1260

tgaccagctt ggctctgata aagaaagtgc atgtaacaga agagcgaggt cgtaaaccag     1320

ccttcaagtg gatcgggcct gtggacttca gctcaagtga tgaagaactg gtggatgttt     1380

ctgcatctgt cttaccagaa ttgaaaagag aaacatatgg ccagattcaa gtctgtgcaa     1440

aacagaagct ggctcgccat ggttctttta acacagttca ggcttctgag aggatccaga     1500

ggaaagtgaa ctcagaaccg agcagcccgt acagagaaga acaaggatca ggtggctact     1560

ctttagaaat tggaagcctg gcagctgtct atagacagaa aatagaagac aattcacagg     1620

gaaaagcctt tgccagtaag agagtggtgc ctccatcaag cagcttggac cctgttgctc     1680

ctttccctgt cctctctgtt gacccagaat attgtgttaa tcctttagcc cacccagtat     1740

tttctgttgc tcagacggac ctgcaggcat tctccatgca gaacggtctg aatggacaag     1800

tggatgtctc acttgcttct gcagcctctg ctgtggagag cctgaagcca gcactccttg     1860

ctggccagcc tctagtgtat gtgccctctg cctcactgtt catgctgtat ggaagtctgc     1920

aggagggacc agcgtcaggg tcagggtcag agagggatga cagaagctca gaagccccag     1980

ccacagtaga gctgtcatct gcaccctcag ctcagaagcg cctctgtgag gagaggaaac     2040

ctcaggagga ggatgagcca gccactaaaa ggcaaagtag ggaatatgaa gacggcccgc     2100

tgtcgcttgt catgcccaag aaaccctcag attccacaga ccttgcctct cccaagacta     2160

tgggtaacag ggcatctata cccctcaaag acattcatgt gaatggccaa ctccctgctg     2220

cagaagagat ttcaggaaag gcaacagcaa actctcttgt ttcttctgag tggggaaatc     2280

cttcaagaaa tacagatgtt gaaaagcctt caaaagaaaa tgaaagcacc aaagagcctt     2340

ctttgctaca atatctttgt gtgcagtctc ctgcaggatt aaatggtttc aatgtacttt     2400

tatctggcag tcaaaccccc cctactgtgg gcccgtcctc aggtcagctg ccgtctttca     2460

gtgtcccttg catggtctta ccatctccac ctctgggccc ttttcctgtt ctctattctc     2520

ctgcaatgcc gggcccggtt tcttctactc ttggtgctct cccaaacaca ggacctgtga     2580

atttcagctt gcctggcctt ggatcaatag cccagcttct cgtcggcccc acagctgtgg     2640

ttaatccaaa gtcgtccaca ctcccttctg cagaccctca gcttcagagt cagccctcac     2700

taaacctaag tccagtgatg tcaaggtcac acagtgtcgt ccaacaacct gagtcccccg     2760

tttacgtggg acatccagtc tcagtagtaa aattacatca gtcaccagtt ccagtgaccc     2820

ccaagagcat ccaacgcaca catcgtgaga cgtttttcaa gacacccggc agccttggag     2880

accctgtcct gaagagaaga gaaaggaacc agtcacgaaa caccagctcg gcccagagga     2940

gactagaaat ccccagcggc ggcgctgact aacctgccgc tttgccaggt gggggtggga     3000

tcaaacgccc tgagagtccc ggatgtccga ggcgggatgc aaaccatccc gtcctgagca     3060

cgggtccttc ctctctcttt catccacact tctgttaact tcccaccacc atcaatcatc     3120

tgatttcctg aaagtaatta attgtgcatt taataccagt tagagttccg actctgcatg     3180

gtgtcacagt gaaagcgccg actgacttat ggttttgatt caagaatcgt cttattctgg     3240

aagtagatct gaataggcta ccggagcctt gtttttctaa aggggggcgc tgtctagcac     3300

ttaactaggg taagcattct taacatgtat ttccacttgc cctgagtaaa tctgtggtga     3360

gagaagcttc ctttctgcag tttaaaaaag ctactgcttc cttaggcttc atcaggaagc     3420

caccttcagt tgtgaatcct atggtgttat ttattttgtt cctgaaatgg gatttagtgc     3480

aaaaagttta caactacagt ctttaacaca tttttttcag ggtatgacga cttgaatgtt     3540

tatactttta ttctataatt tgccctgcac ttattttaca acctagtaat aatgtggata     3600

aatgtatcta catgacacat gtcaagacca aaataactgt gaatgacaca ccttgctgta     3660

aatgaactgt gctaaccctg actgtgggct tgagaacaaa gatgaactct agaactctag     3720

cagcctaact gctgcttctc aaataactgt gtgaacagtg agatattact gtttgtttct     3780

aaaaatccta ctgtgcccag tttccttcac tacatgccct gcatttttta tttaaatatt     3840

tagctgtagc gccatcagat atggatgcct tctaacaatt gctgtttgta aaataaatca     3900

ggatggtaga aagtgattat atggaaaatt ggaacctgga tgagaccttt tcgttgaatt     3960

ctgaagagta atgatgtgaa aattgataca gggcaagaga tgattctttt gtttttcttc     4020

tacttcatgt ccagaagagt aagagggaaa atggacatat gtttcatatc caagggtatt     4080

caaactgtag ttagttggta cctctgaaaa atgagaatgg tgagcgcacg ggttggttgt     4140

tctagcatga atacaattct ggaaactgtt atgcaatttc ccttttttaa cccacattac     4200

tttaggggtg cattaagtcg ccaaactata ctagttcttt gtattcctag acttgctgat     4260

atttacctct ctcttgtctc ttcagagtaa atggttccct tctttccttc ctactttcct     4320

tcattctctc ttccttccct ccttcctact tcttttcttc cttcctcttc ctctcttaaa     4380

actatcttag atgtagaatc ctggtgtagg gttttatttt atttttattt tttgacccaa     4440

taaaatgtta tatgaaagaa tgaaaatatt aatttaagag actctgggag tctgaataaa     4500

gtagctttat attaactaca ggataatatt agccttatta cccccacaag attttttaaa     4560

acttgaggta ggtagctaca ttaaataaat ttgctactta tataaaaatt tttatcaaca     4620

ctaaactttt aaagtttaca agtttttttt ttctttttta cagtcttcta tagagttagg     4680

ttaaaaatgt ggttctaacc atcaacaatt gcatggttaa atgaccctga actaaaactg     4740

atgggttccc tatcaaaaca aataaaaata tacctttttc aggtttcaat ctgtgcaggg     4800

tatatgcatg ttaattctac catgcttaag aacttccaca aaatatttca tggagaggtc     4860

tgcatttaga cggaaacaga aattgctttt cccctcactg ttcctgaatg ctctatactt     4920

gttttaacat ttttgctatc tttttttatt attctgatca tgatatgacc atttaacctc     4980

agaattcata attcctgagg ggtgttaaga agcagtccca ttggtgagga tattatgact     5040

tggtgaccat tcttaggagt agaaaaccaa ggacaattgc ttctgtattc agtatccact     5100

tcttaatgtg gctttatatg taaaaataat aatgcagtgg ttgtttctgt caggaaaata     5160

aatcttacag aacaactggt ggaattgaag ctgctgcgct agacttggat attttgggta     5220

gtgaagaagc aatggcaatc ttgagtctat tattgtataa tttagtaaaa gaaaaaaata     5280

atcgttggtg gtcctactaa gagaatgcag cttttttgag ttgtcacaga ggctgtgtgt     5340

gccctacact gaccagggtt tgtaaaaccc tttcattctg gtacaagagt cgggggtata     5400

acttttatac ttgaatctac ctaccaagtt tacatttctc aattcctttt tgtaaggtgc     5460

tatttctgta tttaaataac tttcttttaa cgtaaagctg ctttctgctt atcttattgc     5520

actgctagtt gtatgtaggt attaatttta ttgctgctta ctgcttttgt tttcttatta     5580

tttagctctg ctctttttcc taatggctat attatctata gctatttact tgtaactgta     5640

ctacatgtaa actgattttt tgttctgatt ttttttctaa tatttttagg aaaatattaa     5700

gctttataaa atagcaataa aaaataattc atttaagaag aa                        5742


<210>  1899
<211>  2666
<212>  DNA
<213>  homo sapiens

<400>  1899
tgtccgtcaa tccgctccgg ttctgccccg ccctcctctt gccgttccct cacgctggcc       60

tcggcgcggc ccgttgttat gacgacatgg tcgtaaatcc gccatcttcc tgcggcgcgt      120

tgcgacatgg agggcgcgat ggcagtgcgg gtgacggccg ctcatacggc agaagcccag      180

gccgaagccg ggcgggaagc gggcgagggt gcagttgcgg cggtggcggc ggccttggcc      240

cccagcggct tcctcggcct cccggcgccc ttcagcgagg aagatgagga cgatgtgcac      300

agatgcggcc gctgccaggc agagttcacc gccttggagg attttgttca gcacaagatt      360

cagaaggcct gccagcgggc ccctccggag gccctgcctg ccacccctgc caccacagcg      420

ttgctgggcc aggaggtggt gccggcagca ccaggcccag aggagcccat cactgtggcc      480

cacatcgtgg tggaggcggc ctctctggca gcagacatca gccacgcatc tgaccttgtt      540

ggtggtgggc acatcaaaga ggtcatcgtg gctgctgagg cggagctggg agacggtgag      600

atggccgagg ccccgggcag cccccaccag caggggctgg ggctcgcagg ggagggtgag      660

caggcccagg tgaagctact ggtgaacaag gatggccgct atgtgtgtgc gctgtgccac      720

aagaccttca agacgggcag catcctcaag gcccacatgg tcactcacag cagccgcaag      780

gaccacgagt gcaagctctg tggggcctcc ttccgcacca agggctcact catccggcac      840

caccggcggc acacggatga gcgcccctac aagtgctcca agtgtggaaa gagcttccgg      900

gagtcgggtg cactgacccg gcacctcaag tctctcaccc cctgcacaga gaaaatccgc      960

ttcagtgtga gcaaggacgt ggttgtcagc aaagaggacg cacgtgcagg ttctggagct     1020

ggagctgccg gcttggggac agccacatca tcggtgacag gcgagcctat agagacttca     1080

cccgtgattc acctggtgac agatgccaag ggcaccgtca tccacgaagt ccacgtccag     1140

atgcaggagc tgtccctggg catgaaagcc ctggccccag agccccccgt ctcccaggag     1200

ctcccctgct ccagcgaggg cagccgtgag aacctgctgc accaggccat gcagaactcc     1260

ggcatcgtcc ttgagcgcgc tgctggggag gagggtgccc tggagccagc tcctgctgcc     1320

gggtccagtc cccagcccct ggcagtggca gccccgcagc tgccggtact ggaagtgcag     1380

ccgctggaga cacaggtggc cagcgaggcc tcagcggtgc ccaggaccca cccatgtcct     1440

cagtgcagtg agaccttccc gacagcagcc accctggagg cccacaagag gggccacacc     1500

gggccgaggc cgttcgcctg cgcgcagtgt ggcaaggcct tccccaaggc ctacctgctc     1560

aagaagcacc aggaggtgca cgtgcgtgag cgccgcttcc gctgtggcga ctgcgggaag     1620

ctctacaaga ccattgccca tgtgcgtggc caccggcgcg tccactcaga cgagcggccc     1680

tacccttgtc ccaagtgtgg caagcgctac aagactaaga acgcacagca ggtgcacttc     1740

aggacacacc tggaggagaa gccgcacgtg tgccagttct gcagccgtgg cttccgagag     1800

aagggctcac tggtgcggca cgtgcgacac cacacaggcg agaagccgtt caagtgctac     1860

aagtgcggcc gtggcttcgc cgagcacggc acgctgaacc ggcacctgcg caccaaaggg     1920

ggctgcctgc tggaggtgga ggagttgctg gtgtctgagg acagccccgc ggcagccacc     1980

accgtcctca cggaagaccc gcacacagtg ttggtggagt tctcgtccgt ggtagctgac     2040

acccaggagt atatcatcga ggccactgcg gacgatgcgg agaccagtga ggccacggag     2100

atcatcgagg gcacccagac agaggtggac agccacatca tgaaggtggt gcagcagatc     2160

gtgcaccagg ctagcgccgg ccaccagatc atcgtgcaga acgtcaccat ggacgaggag     2220

acggcgctgg gcccagaggc ggctgccgcc gacaccatca ccatcgccac ccccgagagc     2280

ctgacagagc aggtggccat gacgctggcc tcggccatca gcgagggcac tgtgcttgcc     2340

gcccgggcag ggacaagtgg cactgaacag gccactgtga ccatggtgtc atcagaggac     2400

atcgagatcc tggagcatgc aggcgagctg gtcatcgcct cgccggaggg ccagctggag     2460

gtgcagacgg tcatcgtcta gcatgaggtc tgcggggtcc tggccgggca gggacagggc     2520

agaggactct gagcgcccca cccatgcctg cctggcctgg tagagaagat ggcacaggat     2580

ggaggcgccc caagacggac agtgtacata agagtttctt gttgctttac aataaaacat     2640

gagaacctgc aaaaaaaaaa aaaaaa                                          2666


<210>  1900
<211>  5288
<212>  DNA
<213>  homo sapiens

<400>  1900
aaccaaacaa cccccaacag ccaagcatac atctctaatt ttattatttt ggtcttttcg       60

ttggattttc cctttcttct ttttttcggg ttatcgctca gttttgagca gaggtttaca      120

ttttttaaaa atttgctttc cagcccgcct tgatcttcta agtgcgagtt catcgtctga      180

gaaaaaaaaa aatctctggt tggcgttttt gtttcttttc ttttctttct tttctttcct      240

tttttttttt ttttaatttt tttcaagggg gaggagattt tccacaagaa aaggttgttt      300

tcatgtttgg gattcaggaa agcatccaac ggagtggaag cagcatgaag gaagagccgc      360

tgggcagcgg catgaacgcg gtgcggacgt ggatgcaggg cgccggggtg ctggacgcca      420

acacggcggc gcagagcggg gtgggtctgg cccgggctca ctttgagaag cagccgcctt      480

ccaatctgcg gaaatccaac ttcttccact tcgtcctggc cctctacgac agacagggcc      540

agcccgtgga gatcgagagg acagcgtttg tggggttcgt ggagaaggaa aaagaagcca      600

acagcgaaaa gaccaataac ggaattcact accggcttca gcttctctac agcaatggga      660

taaggacgga gcaggatttc tacgtgcgcc tcattgactc catgacaaaa caagccatag      720

tgtatgaagg ccaagacaag aacccagaaa tgtgccgagt cttgctcaca catgagatca      780

tgtgcagccg ctgttgtgac aagaaaagct gtggcaaccg aaatgagact ccctcagatc      840

cagtgataat tgacaggttc ttcttgaaat ttttcctcaa atgtaaccaa aattgcctaa      900

agaatgcggg aaacccacgt gacatgcgga gattccaggt cgtggtgtct acgacagtca      960

atgtggatgg ccatgtcctg gcagtctctg ataacatgtt tgtccataat aattccaagc     1020

atgggcggag ggctcggagg cttgacccct cggaaggtac gccctcttat ctggaacatg     1080

ctactccctg tatcaaagcc atcagcccga gtgaaggatg gacgacggga ggtgcgactg     1140

tgatcatcat aggggacaat ttctttgatg ggttacaggt catattcggt accatgctgg     1200

tctggagtga gttgatcact cctcatgcca tccgtgtgca gacccctcct cggcacatcc     1260

ctggtgttgt ggaagtcaca ctgtcctaca aatctaagca gttctgcaaa ggaacaccag     1320

gcagattcat ttatacagcg ctcaacgaac ccaccatcga ttatggtttc cagaggttac     1380

agaaggtcat tcctcggcac cctggtgacc ctgagcgttt gccaaaggaa gtaatactca     1440

aaagggctgc ggatctggta gaagcactgt atgggatgcc acacaacaac caggaaatca     1500

ttctgaagag agcggccgac attgccgagg ccctgtacag tgttccccgc aaccacaacc     1560

aactcccggc ccttgctaac acctcggtcc acgcagggat gatgggcgtg aattcgttca     1620

gtggacaact ggccgtgaat gtctccgagg catcacaagc caccaatcag ggtttcaccc     1680

gcaactcaag cagcgtatca ccacacgggt acgtgccgag caccactccc cagcagacca     1740

actataactc cgtcaccacg agcatgaacg gatacggctc tgccgcaatg tccaatttgg     1800

gcggctcccc caccttcctc aacggctcag ctgccaactc cccctatgcc atagtgccat     1860

ccagccccac catggcctcc tccacaagcc tcccctccaa ctgcagcagc tcctcgggca     1920

tcttctcctt ctcaccagcc aacatggtct cagccgtgaa acagaagagt gctttcgcac     1980

cagtcgtcag accccagacc tccccacctc ccacctgcac cagcaccaac gggaacagcc     2040

tgcaagcgat atctggcatg attgttcctc ctatgtgaaa gaattgcctt gaagaattgt     2100

attaatgaag aggttggatt ctgctacaga gagtaatctg atacaagtcc cagagtggaa     2160

cttttaactc aggccttttt aagaggaatc acaataactg cagattttta aacaaacaaa     2220

atcaccgacc ttgcaaatac tgaaattgga agagggatct gcaagtgcag ggtgttggtt     2280

aaagttgtac ctcccaagta tttgggggat atatttattc tgtattgaca aaagcaaatc     2340

cactttttct ttttcttttt tttttttaag cttaattctg caatcatttg tcttttataa     2400

accgtaaagc tctatacaag ggacactata aataagactc catgttttaa tttatgatgt     2460

ttttaaagct gtgtaaagga agaatgaagt ggtgatattt acaaaaaagt aaaaaaaaaa     2520

aaaaagaaaa aaaggaaaaa aaaaaaagct tgtatgggac agaataggaa tgccagttag     2580

attttttaga aaaactaagg gtcggctttt gcgccttaaa gcatatcaaa tggtagttag     2640

ctcagacagt gcattttcaa tatctaactt aacatgccac cccttagcag tgcaagctta     2700

tttatctctt ttgtattgtt gtcttaagca actgtgtaaa taaatgcagc ctggaaagtt     2760

aaaacgcgat gtaagtgatc acatttttcc ctctactcga aaatccagtg cctctagaca     2820

gattgttaaa actgcatatt taaatctgat ctcattctct ccttttactt aagtcagttt     2880

cttctgaagc cgatggcctc tcgagagctt ggtggcacac atactgtgtg agaatctcct     2940

ttgagacttc atggaacagg gtccaggcac agaattccac actctgccct ccagttaaca     3000

agccaaaacc tcacgtacgc tcccccattt gcaagtttaa agtttactcg tcctaaatgc     3060

agacttcata cctatcttcc aaaagttgat aaaagcaacg tggcaggtat tttcgatttt     3120

cccattccag atactgcctc tatcagtcga cccttaccat ttgtaacata atagattgaa     3180

acaacaggtt aagtgctttg gaattaagag ttaaagggaa ccgggggtgg agaaaggaaa     3240

agaaggttga gacctccaaa acatagtttt ctgttctatg ggaatttttg ctctcattat     3300

ctgggaagtg ttcttaaaaa taagaattaa tagcaaagat gcagcaaagc tctgaggatg     3360

catttgcctg atattttttt ctttgctctt gtgtttttgt atgtagttat aaatactgta     3420

gatttttttt ttgtgatttt ttgccaaagt tgttgttcta tttatacatt ttaatgtctt     3480

aagacatttt ttcaatatca caaaaagatt ttactgcgta ttttgcaaag aaaaaaagct     3540

cactaccttt agcttgcaca tacttgcaaa gttaattaaa aggctttttg ttttaaaggg     3600

gattttgtaa aatatccata taaataatgt atttatcttt cgaatttgta cattgctttt     3660

cccttcttcc tcttccttcc acccccaatt tattttattg tgtatgtttg ctacgtgaaa     3720

agtgcgtatt tgtttggtca cctacacttg tattagctgt ttcaatgtga tttttaaaca     3780

tttcatttat agttattttt agtattgtta taaaccatgc ttcagttttt ttaatttcca     3840

cccaaaagtc attgtctatt tttgtattat ttgtaagtta agaagttttt tccaatatat     3900

ggcaaaaaaa aaaaaatagt agcatattat tcttgtagta tttagttcag tagatttaaa     3960

aaaaaatgta tcctttgctt tggaagctta caaaacaacc ctaatgctgt tttactctat     4020

taatatgcat ggaatctctc cctttggagt gacgcatttt gtgcattaaa ttctagggag     4080

aaacttcata gaaatcaatg aacatacttt ctttcttaag tctgcttgta tatttcctct     4140

gtctttcaca taaatataaa ccagcagatt ggatgcctta acaatgcaaa tcatattcat     4200

ttcacttgta cattgtaact gtgcaccaga actgtcagtc atcactaaca ttctaagaaa     4260

aaagaaaaag aaaaaaagaa aaaaaaaaaa acaaagaaat cgaaaagcac aaaagaactg     4320

ttttgttacc ttaagacaat gtaacttttt ctagtagagc aagaaatcat ttacaacaat     4380

gctgcaactg tgcatgcccc catatggatt ttgcaatggt tttcactagg ctgtcaagag     4440

tgcgattttt atgggttggg gtgggtgggg gaggggagtt gtgggagggt aggggaggga     4500

ggaaagctgt ttttcatggt gagaaataat aatgatgact aataataata aaaaaaactg     4560

gaaaatgtaa gcaaggtgga cgcattgctt ctcggtactc agaaaggtta tctgaatttg     4620

cgtggtaagc gctggcctga agatgtacac aagttaaagc catattttat ctggtgagcc     4680

ccttaactgt ttctgaagga atgaacggtc agccgggaag gtgtccggct tagaccttga     4740

caacagacac tacccatctg tcagccatgt gcagtggtta gaactcttct tgaaagtcca     4800

aagagccttt aaaatgtgta taatttgtgt tttgttgctt ctatttctat tgattagatg     4860

aaaagacatt ctggccctct gatcctcttt cttctccaca aaagttttac aaataaaaga     4920

tgttccccta aatacagaat atggctttaa gaagaaaatg aaatgaagaa ttaaattaag     4980

atttcagtgt tgggggaaaa aatacagctt ctggatgact ggattgcata acattgccct     5040

ggcctcacat tgtactagga tgcagcttaa atgaagtcat ctctaaatct actaaccttt     5100

caccttctta tcaaaacttt ttgaatagac acacactgta cagttcaatt gttagagaac     5160

ctaactactg tagagattgt taaatttttt tttttttttt gcaaaaattc aagctgtaaa     5220

aacttttcaa ctttcacaat atttaattaa agttacttcc tgtctgtgat ggcaaaaaaa     5280

aaaaaaaa                                                              5288


<210>  1901
<211>  9145
<212>  DNA
<213>  homo sapiens

<400>  1901
gctctcatct caaagcgcgc cctcccttcc aggttgggtc ggacctgaac ccctaaaagc       60

ggaaccgcct cccgccctcg ccatcccgga gctgagtcgc cggcggcggt ggctgctgcc      120

agacccggag tttcctcttt cactggatgg agctgaactt tgggcggcca gagcagcaca      180

gctgtccggg gatcgctgca cgctgagctc cctcggcaag acccagcggc ggctcgggat      240

ttttttgggg gggcggggac cagccccgcg ccggcaccat gttcctggcg accctgtact      300

tcgcgctgcc gctcttggac ttgctcctgt cggccgaagt gagcggcgga gaccgcctgg      360

attgcgtgaa agccagtgat cagtgcctga aggagcagag ctgcagcacc aagtaccgca      420

cgctaaggca gtgcgtggcg ggcaaggaga ccaacttcag cctggcatcc ggcctggagg      480

ccaaggatga gtgccgcagc gccatggagg ccctgaagca gaagtcgctc tacaactgcc      540

gctgcaagcg gggtatgaag aaggagaaga actgcctgcg catttactgg agcatgtacc      600

agagcctgca gggaaatgat ctgctggagg attccccata tgaaccagtt aacagcagat      660

tgtcagatat attccgggtg gtcccattca tatcagtgga gcacattccc aaagggaaca      720

actgcctgga tgcagcgaag gcctgcaacc tcgacgacat ttgcaagaag tacaggtcgg      780

cgtacatcac cccgtgcacc accagcgtgt ccaacgatgt ctgcaaccgc cgcaagtgcc      840

acaaggccct ccggcagttc tttgacaagg tcccggccaa gcacagctac ggaatgctct      900

tctgctcctg ccgggacatc gcctgcacag agcggaggcg acagaccatc gtgcctgtgt      960

gctcctatga agagagggag aagcccaact gtttgaattt gcaggactcc tgcaagacga     1020

attacatctg cagatctcgc cttgcggatt tttttaccaa ctgccagcca gagtcaaggt     1080

ctgtcagcag ctgtctaaag gaaaactacg ctgactgcct cctcgcctac tcggggctta     1140

ttggcacagt catgaccccc aactacatag actccagtag cctcagtgtg gccccatggt     1200

gtgactgcag caacagtggg aacgacctag aagagtgctt gaaatttttg aatttcttca     1260

aggacaatac atgtcttaaa aatgcaattc aagcctttgg caatggctcc gatgtgaccg     1320

tgtggcagcc agccttccca gtacagacca ccactgccac taccaccact gccctccggg     1380

ttaagaacaa gcccctgggg ccagcagggt ctgagaatga aattcccact catgttttgc     1440

caccgtgtgc aaatttacag gcacagaagc tgaaatccaa tgtgtcgggc aatacacacc     1500

tctgtatttc caatggtaat tatgaaaaag aaggtctcgg tgcttccagc cacataacca     1560

caaaatcaat ggctgctcct ccaagctgtg gtctgagccc actgctggtc ctggtggtaa     1620

ccgctctgtc caccctatta tctttaacag aaacatcata gctgcattaa aaaaatacaa     1680

tatggacatg taaaaagaca aaaaccaagt tatctgtttc ctgttctctt gtatagctga     1740

aattccagtt taggagctca gttgagaaac agttccattc aactggaaca tttttttttt     1800

ttccttttaa gaaagcttct tgtgatcctt tggggcttct gtgaaaaacc tgatgcagtg     1860

ctccatccaa actcagaagg ctttgggata tgctgtattt taaagggaca gtttgtaact     1920

tgggctgtaa agcaaactgg ggctgtgttt tcgatgatga tgatgatcat gatgatgatc     1980

atcatgatca tgatgatgat catcatgatc atgatgatga ttttaacagt tttacttctg     2040

gcctttccta gctagagaag gagttaatat ttctaaggta actcccatat ctcctttaat     2100

gacattgatt tctaatgata taaatttcag cctacattga tgccaagctt ttttgccaca     2160

aagaagattc ttaccaagag tgggctttgt ggaaacagct ggtactgatg ttcaccttta     2220

tatatgtact agcattttcc acgctgatgt ttatgtactg taaacagttc tgcactcttg     2280

tacaaaagaa aaaacacctg tcacatccaa atatagtatc tgtcttttcg tcaaaataga     2340

gagtggggaa tgagtgtgcc gattcaatac ctcaatccct gaacgacact ctcctaatcc     2400

taagccttac ctgagtgaga agccctttac ctaacaaaag tccaatatag ctgaaatgtc     2460

gctctaatac tctttacaca tatgaggtta tatgtagaaa aaaattttac tactaaatga     2520

tttcaactat tggctttcta tattttgaaa gtaatgatat tgtctcattt ttttactgat     2580

ggtttaatac aaaatacaca gagcttcttt cccctcataa gtagtgttcg ctctgatatg     2640

aacttcacaa atacagctca tcaaaagcag actctgagaa gcctcgtgct gtagcagaaa     2700

gttctgcatc atgtgactgt ggacaggcag gaggaaacag aacagacaag cattgtcttt     2760

tgtcattgct cgaagtgcaa gcgtgcatac ctgtggaggg aactggtggc tgcttgtaaa     2820

tgttctgcag catctcttga cacacttgtc atgacacaat ccagtacctt ggttttcagg     2880

ttatctgaca aaggcagctt tgattgggac atggaggcat gggcaggttc tcctttcttt     2940

ggaaacacat ccatgctggg atgcacagtt cttttcctaa ggattgtgtt tactcctgac     3000

tgcaacgtct tggccactgt ttggagcagt ttggtctgaa ggtcattaag gatctgcttg     3060

catcttgttt catgtcctcc gtgacagact gcagaccatg ttagaagaga aggaaggttt     3120

gtggatcaag agggttgaca ttaggtttgg tgagatgagt tgcttggcac agatcagcag     3180

aacaggaccc tggtgataag gcatctggct ttgctaacca cttatcatct tccattattc     3240

tctttcttaa ctaagtagac ccgaaagtgc acttttgaag tctggtttag atggcgagat     3300

tccgaatcta caatgatcga gtactggtgg ccacttttct ccaacattaa gtaaagagga     3360

ggagattcca ccttcagaaa gtgctgggaa gcattggctt tcttcccaca ttggtagaag     3420

agatggagga ggaaaccagg gtgcacattt ctacagatcc cctttgcctg ctggtgtttg     3480

ccttgtaaga taagtcactg gggggaaggg gaaatctatg aaatccaaga taaaggcata     3540

gtctttcagc tctattggtg ttaaaagtat atttgtgtcc aaatgttaat caacacaaat     3600

gtacagtact cagtactgac ttttttcact tcaaaatgtt ttcaagggaa attcagcaga     3660

cacccaactg tatttaatta gtgaaaagat ctataaagac tcttactttg aataaacaca     3720

ttaagtaagt gtgtcaaaat atttggaatg ccagttatct atgagcgcat atctcttaca     3780

gagtgtattt tgttttcatt aaggtatctc tgtgtatcta cactggacta atttcatagg     3840

gatctgattc tatgtgatcc actgtagaaa gctactgatt acttctgcag taacagcagc     3900

tctaattagc atcagatgac caaagcggaa atgggagttt cagcgctaac aagggcagcc     3960

ttcattgaag aatgcatggg taggcaatat ataaattaca ttttgaaaag cctcatctgt     4020

caccaacaaa tatctcattt ttcttcagtg ataaaagcat attcaagtta ccagctcctc     4080

aatttgaaaa tcagttgctg attaaataaa tagggggaag catcttgttc agggacaaca     4140

cgttagagag attcttatca aagcaagcca agcaaggttt ccgccattca gtgtgatctt     4200

agtttgacac ggtgacccta aaacaccatc atttgcccca gaactggagc acaataagtt     4260

aaatcattta cctgtctcac ttcttcttgg cgtgcttaaa agcaaaaatg attcgctact     4320

tcctgtcctt cagtccgggc atttggggtg ccactgaaga caggggttat ctgctgaggt     4380

ttgggtgtct tgcaggaagt atctcattgc agttgatttt gatgaaacca aacagtaact     4440

agggtccatg cagaccgtga ctccctgatt acatctagcc atgccctact tatttcagag     4500

agaaagagag ggggaataaa ggcagtattg ccacactgat tagaagcaca ttcattccac     4560

tttgatgttg aatatttttg accgatacat gcttgagtat ctttttaata gagcacatga     4620

aggaagaagc acacaatata gagaaggaat tgagaatgcc aattacatat ttatttttcc     4680

atacctgatt tttttcaagt ctgtaataaa aaaagtataa gttgagatta acataggtta     4740

tttttcatga agtatagcaa acgatctaga atgtgatagg agtgtggttt ccatttcttt     4800

tttttttttt ttaacagact tttgtgctgt agtaagaatg tcttagaagt tgtgtcttcg     4860

agttcctcaa acaccggaca gggctccccc agagctgcct cagcctttga tttggtccat     4920

attcagacac ttcctgtctt gcatacactc tgaggatggg ccgcttctag ctgccgcccg     4980

tctccctctt gccttcttgt ctctaaatca gacactccca agcactccat ctgctatact     5040

aggagagtgg gagagccaaa gcattttgga gtccatgtaa agtgcctggg aaaagagatg     5100

taagagcagt gggagtttat ataattagcg aattcttttc tcagaattca gcggaaatgt     5160

atttctgttg ttattattta caaaattgtg gcctcagagg agctgtcttt tggaaaataa     5220

gttttcattc atgcagttag ttagacatgc acgatgtact tgaatcaata aactgtggac     5280

cagaaaaggg ctgcttaaat gaattcacgt gttctaattc tctttcgagg ctgttgatga     5340

cctcctggat tcataccccc atgatctgtc ttgctcttgc ctctgttctt tgataaagca     5400

catcagacta tgtgacaccc atcttttcaa gaacgaccta aaagcaatga caacaggcag     5460

gagagaatta ccactggcct gggcacagtg acagcagaag gcccacctga gcttggagag     5520

ttggcgagat aaggcaaaat caaggtgcaa cagtgggcca tgttccaagg gtgaatggat     5580

ctgagagtcc gctgatgttc cttactgatc agaacaggga ccttctaacg aaacagccag     5640

agttccttga atcaggcaga agttctttag agacaggaag ccagagctat tgataatatc     5700

cgaacgacag aggaaggaat ttcttattag aaattctaaa ataaaacaag tggggatttg     5760

gttggatacc cttagaagct acatttttct ctcatcccta agatagatat ctcaagtgta     5820

tatctgacac ctcttggctt tgacacggct ctgcttctca agtgaccatt tgttttaagt     5880

ctgttgtcta gaattctttg tgggggctgg acctctgaaa aagattctca ctgcagaggc     5940

tttaaatctg tgtttttttc cactccctcc gtcctgggat gtattcggta ggacatttca     6000

tttatatcag gatattggct gattcagctc tctttcatcg ttattattca ggcctccctc     6060

caccaccttg ttctttattg cctaagtatt gccctcccca attcttcatc gtaatagctc     6120

taaatttagt ttgacccaaa ttaatttttg ttccaacaga tatattttaa gacagagaag     6180

cctctctcag gagccagatg atctgaagat gatgctaatc cccaaatacg aagttcctcc     6240

agctaactct cctctgagct ccctcttctt agctttggga ttggggatgg tctcatcctt     6300

gccaggaatc cctttgttgc tcccagtgtc tctgatgagc ttctcctccc tcccagagac     6360

aatgcagggg tggttttcag cagaatgtgc cacctgcact tctgattgtt ctgagaccca     6420

gcccagaggg gtggagaagg cgcacaaacc ctattccaat aaactgcctg cagagaacca     6480

cagcctgcta atagtcgttg aggtctcagc cccctaaggt ctccaagctc atttgaccag     6540

cgcagctgcg acttcggctg tctgcctctg gcaggtgcca atatcagcat cttgtcccac     6600

tgccatgggg agttaatttt tgctccaggg cagctgccaa gcccagcacc ggcatcaata     6660

gaaggttttc tctgattttc ttctcttcct ctcaggctag gctttcttac caatccccaa     6720

ttttcttctg tagggcgcca ggagactggc cagagatctt tagactctta cttagtttga     6780

acatctcttg ctgctcacac ccaggcttct tcagcagaaa gcatgaccca tagtaggtac     6840

tcagaaactg gttgaatgaa aagccttgac atttaagggc tttattctgt catacggtag     6900

caagaactgg cctattggca tcgtattcct ggcattgagc tgtattgacc ctgaatgtgt     6960

cctcctgagg tttttgaggg tgacctagga gaaagggtct gaaaaagcac tgggatccaa     7020

gtgactttaa atctgcccgt ggcatttcct gctgagaggc gagaaactag catctctccc     7080

aacaggctca catccgccag gaaggacaga gcccaaaacg ggggtagact ttgtgggaaa     7140

ttcgccagtt agtccgctga gattttaatc tgcctcaagc acaggatgct gacaagaaag     7200

gtagaccact cccccgatcc cagacaaacc ccaggggtga caacttctcc atcagtatcc     7260

tgagaagcaa catcaaatgc ttaccaagtc agcacgttta ctgagtgagt actctgacgg     7320

aataaaccag catttggagc tgaacttgag aacacagggc cctctgacag cagcttaggg     7380

aaacacccat cccttccaga ttggcagaat ccttccattt catgtccttc ggagacgctg     7440

tattctcttt acaaatcatt catgaaactg agactcagtc tcccaggggt aagtcctggg     7500

ccacgtgcaa acaatggcaa atccagctct tccatgatag agaaggcaaa cacacccacc     7560

ttcatcctga gcctaaaagg ccacctctga gcacttgggc agccactcct ctgggcctca     7620

gagggccatg agcttggcca ggtaggcaca gcggcgggga agtcacagct gtcaggtacc     7680

ggccatggtg caggtgggaa taggagatgc cagagctgct ttagctgagg aaagcaaaca     7740

gtcagcagtg ctcaaaggag caaaacttcg aatgtgcaca ttgacccctg acacctgcaa     7800

gcataacaca gatcctaaga ctagagtgaa gtaggaagaa gaattagaaa atccagtgga     7860

tgtcctgagt atagggaacc agggccgttg aaaatcagta aaggttgatt acctggggcg     7920

agaccgggtg actgtggcag tgcaggtgaa ggtaccctgg accttctcag ttcgctggca     7980

cataaggctc cgccaataaa gcgtggttct ctctgtcaca cacacacaca cacacacaca     8040

cacacacaca cacacacaca cacacacaat gattggaggg ctatatgatc cagcattagc     8100

ttcctggtgt gccaagcatg cttgatcggg aatttttttt tattattatt attttttagc     8160

tgtagctgaa ggcatttctc ggatgtggag aggagaatgg aaatcgcaga accaaatcag     8220

tttgccctgc catatttggc tgtggtctgt cattgggcat ttctgatgtg cttttctgga     8280

ttcaggaaga gctgattgtc ctccgagggt tgaaaaaaaa aaaacagttt cagaaacctg     8340

aatccagggc cttatagttc tcctcattat ctatcttctt ctcccttccc tcgcccaagg     8400

gagtggggga aacacttttc actgcagagt ttgctttaaa gttttcccat cttgcgtgca     8460

ttatcccttg atattaaaat tattttctca gtttaatcca actcctgctg agaagctgtg     8520

tgagatttag gctgtggggt ttttttcttg tactcttttg gatggtgttg catttttcac     8580

tcttaacccg agggtgtgtt tcagcttatg ttcgttctgt ttcatgcagg tttatagcac     8640

ggtagagtag aaggcggctt ctgattttta gggtattttt agaattcatt cctgagtgag     8700

gggttcagac acccagtctc ctcggaacag gggtgagggg tcgactgagc tttgttgaga     8760

agcctccagt taggcttcgg gcgggtctcc atgttatatt gtgtgtttac tgagcttccc     8820

actggtagaa gatgacacat ttgtccatcg tcctgtgtat ctgctttcca gaggacaccg     8880

gagcattctc ctggggtcac tcccacatgg ctgcctcaca tagctgtttt gcaacagcct     8940

ttattgccaa cacccttgga agaacatctc ctgtagaagt acaagttttg caatatggac     9000

tttggaagtg gttttgtgat gttcgaattt tctgttagcc tattgctcaa gcactacaga     9060

atgtacatag tccctttggc catcctctca ccccagaata tcctaataaa cattgttttc     9120

ttttttaaaa aaaaaaaaaa aaaaa                                           9145


<210>  1902
<211>  5507
<212>  DNA
<213>  homo sapiens

<400>  1902
gtaatgctga gacagactcc cagaagatct gagcgagtcg cgtagctgag cccggcaggg       60

gctggggtgg tgctgctgct atgagctgca ccatcgagaa gatcctgaca gacgccaaga      120

cgctgctgga gaggctacgg gagcacgatg cggccgccga gtcgctggtg gatcagtcgg      180

cggcgctgca ccggcgggta gcagctatgc gggaggcggg gacagcgctt ccggaccagt      240

atcaagagga tgcatccgat atgaaggaca tgtccaaata caaacctcac attctgctgt      300

cccaagagaa cacacagatt agagacttgc aacaggaaaa cagagagcta tggatttcct      360

tggaggaaca ccaggatgct ttggaactta tcatgagcaa atatcggaaa cagatgttac      420

agttaatggt tgctaaaaaa gcggtggatg ctgaaccagt cctgaaagct caccagtctc      480

actctgcaga aattgagagt cagattgaca gaatctgtga aatgggagaa gtgatgagga      540

aagcagttca ggtggatgat gaccagtttt gtaagattca ggaaaaatta gcccaattag      600

agcttgaaaa taaggaactt cgagaattat tgtccatcag cagtgagtct cttcaagcca      660

gaaaggaaaa ctcaatggac actgcttccc aagccatcaa ataactgaac tctgaatgat      720

ggctggagat tgtctatcaa ggaaggaagt tactgtcttc ccattcaagt actgtccatt      780

aagtgtcttg cctcagattt gatttaatct taattaaagg tatcaggtgg caatttagaa      840

ttccagtcaa tattggctgt ccacagttct cagatgtgtt aatgtgaata ctacatgctg      900

aatttcacca ttcctttctc aaagagacta cttttaattt tcatttctgg gaccttgatt      960

tatataaact atgttttcag ttctttgtta tttttcacat ctctgaaact ttgagcattt     1020

tttataagcc agcaatttat tttacatagc attgtaaaat acacttctag gaaattttag     1080

gaaagattta actgtttaaa tctatttggc ataaaccttg attttttttt tccatttgac     1140

aaaaataata caattccaca gaactagatc agcagattct ctgatttgta atgtcattca     1200

cctgtgacat tttaagtctc tctggtgcta agaattggca ctttatagcc tggtgccttt     1260

acttttaatt tgagagaacc tactgctagt cccaggaaac acacttggaa ataagtcagc     1320

tatttttttt gcccagtgat gctatagttg tcatattgtc caaagttcat attgttcaaa     1380

gctgaggagc ttgtcctgtg tatgtgaatg cacacatgtg cacttagttc aaatactaaa     1440

agtagctttt attaaatata atcagccaaa aacacacaca aaataaaaaa aacaaatata     1500

agtagtcagt ttttcaatgt tatcctacta gttctacatt ctattttaat ttttatacaa     1560

tttccatttt atagttaaga accatcactt acttggattg gatgtctttc attcctagca     1620

ctaatagttg gctttctttt tttttgttta catagaagca gggttttttt ttatcttttt     1680

tctttttttt tgtttaagct atataaaaag gtgaggaagc agttttgtta cctaatgaaa     1740

attattacac tcataatgct gtgtaggcaa cattgagatt caaatgccca gtggtcaact     1800

gggttcactc atcaactcat tcccgtccca gtttactcac atttcaaatt tataaatttc     1860

ttcatgttat actattctat ttagatttgc ccagaattag ttgaaataat gctaaacctg     1920

tcaatatttt ccagtaacat taagcaccat actgcatggg agagacacag tactaaaaag     1980

agttgttagt gctttatgtg agtgatattt ctttcgtaat gctataaaga actacagtta     2040

aaataacaaa atattttaaa gatgtcctaa aagcatctga tcccagtaat aactaatgga     2100

tgtcatctag agcagtgggt gttaatgaat aggtatatgt catttaagaa tttttcaaat     2160

ttctgtttga tatcctgcat agaatttgac aaaaaaaaca cttccaagtg tgagcatttt     2220

ttatttcatt tcccaagagt aagtaagtaa ctattagccc agccatctgc ctcgaagtat     2280

accttaagtg accccataaa tccattcaag aggcaggtac tctataccat ttggcagcca     2340

cggccaaacc taccatggcc agatttcagt gaaaatgatg aagtaatcaa atcaaggtat     2400

aatatggtgt ccctttatgt gctttatgtt cctttagagc tgtttataaa gttctttata     2460

tctcaagtgt taggataaat cgacatacta acttttcccc ctgcaaaatt aaaagcctga     2520

ggtacaagtc taagaagctt ttagtgctct acataatata aattctggct ggtgttaatg     2580

ctatgaagat aatatgtagt tagaaaattg agtcggggag gaatgctctt cattttaagt     2640

ggattttaaa gtttctcctt gagtggatga agaacttgcc tggtttgcaa aaatcttagt     2700

tcaaaattat attttctaac aaaaactgca ttttgagaag ataagctaat tttactcagt     2760

agtaagtcaa atgaggaagt gcagagggtt tttttacata tatatagcaa ccttgtcaag     2820

tggtcctcac aagagtcata aatactttgt aattagcaca gtatattcag cagtgtataa     2880

ctctacaaat agtaccttat attagtgtag tattatatca atatcttatg tataattctt     2940

atattaatac cttatgcata attggattca aacattgaag gtctatttta gtgttcttca     3000

aaatgtgctt ccctgaccta ctgaaataga aacttggtga tgaagttcaa gaatttgtat     3060

tctaatcatc tcaaacaatt cctaaagaca ctgattttaa aatatctagt ctaggcccca     3120

ttgtgtaata gttagcactc taaaagatga aaaagaaaat agtctatgtg ccaaccactt     3180

cattagtact tatgaattta aaaatgaaaa agtctggtac aggagacaag tatatatata     3240

aaattataat gcagtgtgat aaatccatta tagtatgtat aagatacaga agagggactt     3300

taaacttgag aattcaatag agataataaa tgggtaggag ggaaatagaa aactttggtg     3360

ccacaaaagc aaagtatgta tggtattgcc aataatagct accatctatt gagtgcttta     3420

ctacctgtca ggtactgtat tatataaact ccattttaac tgtacctcat tttgcagata     3480

ctcaggcaca aggaggtggt tatttgtcca aactggaacc aagattcaaa cccagacaga     3540

gtcttaagca catttttaat cactaactaa cttgagatgc ctaaatgcca aatactgttg     3600

ggagttcaag tggttcttga ttagcaaaat ctatttttat tagtgcaaaa gaaacaccac     3660

agcttataaa gtattatgaa ttcaataaat ggagtcttaa ctaatgagat attattttct     3720

agaatggtgt agctgagagt atgtgtgatt caactgaaag gaataatgtt taatcagtga     3780

ctcttactat atacaggaaa aggtgcagtt ctgtctttca aatctgcctc cttaccatat     3840

tggcttacat ccctcatgct gttttcttgt gtttgctaga aagttgttgc caagccaaat     3900

gtcatggcca tgttgaaggc aaggaagaaa aaatggaaat ggcctgtgcc agctatatat     3960

atcgcctttt atgagggaaa gcaaagcttt ctcagaaatc ccaaatggat tttcccttga     4020

cttaattgcc tgaccagtta aatggccact ggtacctgca aagaaagcag ggtacatagc     4080

tgtcccaaat aaaatcagta ttagcaagaa gaaagaatat tgagaaagca attaacagtg     4140

tctgtgactg tgacatgtct gtgactttat attgtcaagt cctttcccct tgaatatagt     4200

tttggaagaa ttagctgaag gagtgtgttg acattgaatg gccaagagaa tgggctgtag     4260

cagacatctg tcatttctct tttggctgcc cagtatccta actcctgtgt ttaaggaatc     4320

cctcacctaa tgaggcagag catttcttcc tcctaaagaa tttgaaagta ccaggtaatg     4380

ttttctcagc ctccttttgc agctaaggaa gaaacatctg ccttcaattt taaaattagt     4440

gatacaaaga aggagggaac catgcagatt cctttgaaga tggtgattaa caacactact     4500

gcattcatct ccacagaggt acagcaaaag tgatttagtt agcgataacc tctaattcta     4560

tttttttatt tttatttttt gagacagtct tgctctgtca accaggctgg agtgcagtag     4620

cactgtctta actcactgca acctccacct cctgggttca agcgattctc ctgcctcagc     4680

ctcccaagtc gctgggatta caagtgccca ccaccatgca cagctaattt ttgtgttttt     4740

agtagatggg gtttctccat gttggccagg ctggtctcga acttatgact tcaggtgatc     4800

cgcccgcctt ggcctcccaa agtgctggga ttataggcgt gagccactgt gcctggcctg     4860

taacctctaa ttcttgtttg ctggctgtcc tagagatcct gagaattact tttaataaaa     4920

tcattttttt gctgttatta aaactaacct gaattgccta aaaccaagaa ctctgcttga     4980

taaaataagc atagttttag gaacagccat gcagatataa attttatcaa cactttatac     5040

ataatttggg acttatattt aaatgtaata tttgatgctt ataaaagggt aaatggggaa     5100

tgcaaataaa ttatcaagca taataactca tcacctaact taagaataac attatgagtg     5160

cttgtatttt atctatttga gctcttctcc tatctttgcc gacccccccg ctctcttttt     5220

aatagatttg ttcgaatgta gaaagaccta aaatacatat gtatccctaa agtgacttat     5280

tttatagttt tctttctttt tgaacttcaa aaaaattgta tcatactcta tgtagtctaa     5340

ggatttggtt tttttcactc aacatgtctc tagaattcac aagttttatt gttttatagc     5400

tgtcattttc attgatgtat atttcattgt tgggttatac aacatattgt taaggaatac     5460

atacatatat aataaattat acatttttta aaaaaaaaaa aaaaaaa                   5507


<210>  1903
<211>  3049
<212>  DNA
<213>  homo sapiens

<400>  1903
ggcgagggtc ggggccaccg cgcggcgacc tcgggtcccg gagcgaccgc agggcagccc       60

cgggcgccgg ccccggtgcg cgtctcctgt gcgcgcccct ccgcgcgcgg ccccgatgct      120

ggacatgagc gaggcccgct cccagccgcc ctgcagcccg tccggcaccg ccagctccat      180

gtcgcacgtg gaggactcgg actcggacgc gccgccgtct cccgccggct ccgagggcct      240

gggccgcgcg ggggtcgcgg tggggggcgc ccggggcgac ccggcggagg cggcggacga      300

gcgcttcccg gcctgcatcc gcgacgccgt gtcgcaggtg ctcaagggct acgactggag      360

tctggtgccc atgccggtgc gcggcggcgg cggcggcgcg ctcaaagcca agccgcatgt      420

gaagcggccc atgaacgcat tcatggtgtg ggcgcaggcg gcgcgccgca agctggccga      480

ccagtacccg cacctgcaca acgccgagct cagcaagacg ctgggcaagc tgtggcgctt      540

gctgagcgag agcgagaagc ggcccttcgt ggaggaggca gagcgccttc gcgtgcagca      600

caagaaggac caccccgact acaagtacca gccacggcgc aggaagagcg ccaaagccgg      660

ccacagcgac tccgactcgg gcgcggagct gggaccccac cctggcggcg gtgccgtgta      720

caaggctgaa gcagggcttg gagatgggca ccaccatggc gaccacacag ggcagaccca      780

cgggccgccc accccgccca ccacccccaa gacggagctg cagcaggcgg gcgccaagcc      840

ggagctgaag ctggagggac gccggccggt ggacagcggg cgccagaaca tcgacttcag      900

caacgtggac atctcggagc tcagcagcga ggtcatgggc accatggacg ccttcgacgt      960

ccacgagttc gaccagtacc tgcccctggg cggccccgcc ccacccgagc cgggccaggc     1020

ctatgggggc gcctacttcc acgccggggc gtcccccgtg tgggcccaca agagtgcccc     1080

gtcggcctcc gcgtcgccca ccgagacggg tcccccacgg ccgcacatca agacggagca     1140

gccgagcccc ggccactacg gcgaccagcc ccgaggctcg cccgactacg gttcctgcag     1200

cggccagtcc agcgccaccc cggccgcccc cgccggcccc ttcgccggct cacagggcga     1260

ctatggcgac ctgcaggcct ccagctacta tggtgcctac cctggctacg cacccggcct     1320

ctaccagtac ccctgcttcc actcgccgcg ccggccctac gcctcacccc tgctcaacgg     1380

cctggccctg ccgcccgccc acagccccac cagtcactgg gaccagccgg tgtacaccac     1440

cctgaccagg ccctgagggc ccagccgcgg ggagggactc gcaggcgtca gggggcagcc     1500

ttgtcccggc ccagtgtgtg tgaccagggc gggaggggcc ccagtggctg agctccaagt     1560

gcctgctgaa gtctgcaggg aaacacgctt gctgcccgtg gccctcggcc tccagatggc     1620

cacacctctg ccgacgacgg accagctccc tctcccttct atctttcttt ttgaggtggt     1680

gggattattc cacaaagaag ggctgccgtt tggtccctct tccgtgagga ctggcggcac     1740

cagcaccttc gctttgcatc tcggtagagg agaaacggca gcacagccca aggaccaaag     1800

gagggggtgg caggggcctt gcagggcgct gtgaggtcca ggccggtctt ggcgccgaga     1860

gcccctgcac tcaaggccac attccctcga caacggctgc acgggctgtc cgggatccgg     1920

ggtgtctgtc cgcagactgg gatgagtcta ctcgagcatc tccgggacct gcctgtcaga     1980

tctgaggtgt ctccttgctg gcagagtgcg ctcacgcgag ggctggctgt gatgaacaca     2040

tctctctttt atttttatgt ttttgataat ttttattttt gaagcttaaa tgtgtttctt     2100

ctgaaagctg ttaaagatgt atttatgttc tgtgttattt tatctttaat taatgaggta     2160

attcgggcaa agagtagaat ttaagacaaa acggaagctg ggaagcttcc cttgagggca     2220

ggcaggaggt ggagttgcag ctgttggccg gcatcacgtt gctcgttgct cggcttatgg     2280

gaggccgccc tggagggccc ggaggtccca aggtccctgg gaggactggg cccctcatgc     2340

ctcgagcttg gcaaccgaaa acccgaggga ggagaaggga cctgccttgt gacatctctg     2400

atcaggttgg ggtgccccag cacccagtac cagtttgggg tttgggaagc aggactccgt     2460

ccctgtcccc gactgtgcca cgtggtagga cacataggac acaggaattc ctgggtcctt     2520

gcccatgact gtgccatgtg gtaggacaca ggacacagga attcctggaa agtggtggct     2580

tcagaagtga tcttggctcg caggcaccag tgccacctac caagctgtga aactaaacct     2640

tctccactaa acgtcgttag ggcctcagtt ctagacgagt catacctgat tcacctgcac     2700

tgcttcccct gtgtgctgag catagagcat acaatagcgc ctacttcacg gaaacttgtg     2760

cctttaaact ttgtaaactt aaacacagcc gagaagttgc ttctttgtac tttttctact     2820

tttcctactt ttttgtagaa aaaaaagata atgcctctgc ttctatttct ctgggggtgg     2880

gggtgggggc cgggagccgt cgcagacccg tttcatgcag cgtctccctt ggcaccgcgt     2940

tcggaggacg caccctcact cccctgctgc cttcactcct ttctgaccaa gcaacgctaa     3000

cttttgtaca gatcgatttg ataaaattaa acaaagtgct ttttatgga                 3049


<210>  1904
<211>  4350
<212>  DNA
<213>  homo sapiens

<400>  1904
ggggacgggg ggaggggcgg gggtcacgtt acgcggagga cgcgcgggca gcgccgggag       60

aaccgaaccc ctggcggccg cgaccccggc tcccgccccg gccccggccc gacccgccat      120

gacggggctg gaggaccagg agttcgactt cgagttcctc ttcgagttta accagcgcga      180

cgagggcgcc gccgcggccg ccccagaaca ctatggctat gcatcctcca acgtcagccc      240

cgccctgccg ctccccacgg cgcactccac cctgccggcc ccgtgccaca accttcagac      300

ctccacaccg ggcatcatcc cgccggcgga tcacccctcg gggtacggag cagctttgga      360

cggtgggccc gcgggctact tcctctcctc cggccacacc aggcctgatg gggcccctgc      420

cctggagagt cctcgcatcg agataacctc gtgcttgggc ctgtaccaca acaataacca      480

gtttttccac gatgtggagg tggaagacgt cctccctagc tccaaacggt ccccctccac      540

ggccacgctg agtctgccca gcctggaggc ctacagagac ccctcgtgcc tgagcccggc      600

cagcagcctg tcctcccgga gctgcaactc agaggcctcc tcctacgagt ccaactactc      660

gtacccgtac gcgtcccccc agacgtcgcc atggcagtct ccctgcgtgt ctcccaagac      720

cacggacccc gaggagggct ttccccgcgg gctgggggcc tgcacactgc tgggttcccc      780

gcggcactcc ccctccacct cgccccgcgc cagcgtcact gaggagagct ggctgggtgc      840

ccgctcctcc agacccgcgt ccccttgcaa caagaggaag tacagcctca acggccggca      900

gccgccctac tcaccccacc actcgcccac gccgtccccg cacggctccc cgcgggtcag      960

cgtgaccgac gactcgtggt tgggcaacac cacccagtac accagctcgg ccatcgtggc     1020

cgccatcaac gcgctgacca ccgacagcag cctggacctg ggagatggcg tccctgtcaa     1080

gtcccgcaag accaccctgg agcagccgcc ctcagtggcg ctcaaggtgg agcccgtcgg     1140

ggaggacctg ggcagccccc cgcccccggc cgacttcgcg cccgaagact actcctcttt     1200

ccagcacatc aggaagggcg gcttctgcga ccagtacctg gcggtgccgc agcaccccta     1260

ccagtgggcg aagcccaagc ccctgtcccc tacgtcctac atgagcccga ccctgcccgc     1320

cctggactgg cagctgccgt cccactcagg cccgtatgag cttcggattg aggtgcagcc     1380

caagtcccac caccgagccc actacgagac ggagggcagc cggggggccg tgaaggcgtc     1440

ggccggagga caccccatcg tgcagctgca tggctacttg gagaatgagc cgctgatgct     1500

gcagcttttc attgggacgg cggacgaccg cctgctgcgc ccgcacgcct tctaccaggt     1560

gcaccgcatc acagggaaga ccgtgtccac caccagccac gaggccatcc tctccaacac     1620

caaagtcctg gagatcccac tcctgccgga gaacagcatg cgagccgtca ttgactgtgc     1680

cggaatcctg aaactcagaa actccgacat tgaacttcgg aaaggagaga cggacatcgg     1740

gaggaagaac acacgggtac ggctggtgtt ccgcgttcac gtcccgcaac ccagcggccg     1800

cacgctgtcc ctgcaggtgg cctccaaccc catcgaatgc tcccagcgct cagctcagga     1860

gctgcctctg gtggagaagc agagcacgga cagctatccg gtcgtgggcg ggaagaagat     1920

ggtcctgtct ggccacaact tcctgcagga ctccaaggtc attttcgtgg agaaagcccc     1980

agatggccac catgtctggg agatggaagc gaaaactgac cgggacctgt gcaagccgaa     2040

ttctctggtg gttgagatcc cgccatttcg gaatcagagg ataaccagcc ccgttcacgt     2100

cagtttctac gtctgcaacg ggaagagaaa gcgaagccag taccagcgtt tcacctacct     2160

tcccgccaac gttccaatta taaaaacaga acccactgat gattatgagc ctgctccaac     2220

ctgtggaccg gtgagccagg ggttaagtcc tctcccaaga ccatactaca gccagcagct     2280

cgcgatgcca cccgacccca gctcctgcct cgtggccggc ttcccgccct gtccgcagag     2340

aagcaccctg atgccagcgg cccctggcgt gagccccaag ctccacgacc tttctcccgc     2400

tgcctacacc aagggcgttg ccagcccggg ccactgtcac ctcggactcc cgcagccggc     2460

cggagaggcc cccgccgtcc aggacgtgcc caggccagtg gccacgcacc ccggctcgcc     2520

cgggcagcca cccccggccc tgctgccaca gcagtaaatg aaataatacg aaatgacctc     2580

tccagcacga gcacccactc ctagttgcca cattggagca ctcagttcag caggggtatg     2640

ctgacttcag cagacaaaga cttttgaata aataaactga actcacacct ggtaccactc     2700

agaacctcca actgactgaa tgccaggagc tgaacattaa tatgtgcaaa gattggctct     2760

ccaacaagaa ggaaagcagg gaggaaggga gaccactgtg tcacctggag gagaagtcat     2820

ctcatgacaa cagaagggag gtggccgggc tgagcacggg agacccaccg tgcaggggcc     2880

tttcatggga acggcccaca cgcagtttga ccccacgccc agcccttctg gcacccctgg     2940

ggttcaatac tggaagtgcc ttatttaacc agaccatcag ggcatcatag aattgagcat     3000

tgaatttgct actgtaggag tatttttagg agcagaaact gcaaacacat ttcattgtga     3060

ggttttaccc tctgtatgaa tgaagagaac gctggaaggc tgcgagagga ctctagtatg     3120

agtctccaac atttggaacg tttcctgggc tgtcacgtac actcctgctg ccttacacag     3180

tgcattttag aatcttccag tctgtcatct cagctctttt gtaacatgct tcccttgtct     3240

gcgcggttga aaccgtaggc ttgttcatag tcgcatgctc gcatctttgt ttttaatctg     3300

gcttcgaaca tagcacaagt aacttgaata gcacatcaat aggttactgg acaaaagcag     3360

aaaaacctgt tacaggatag cctgcatttg catgtgtgta catatctagg catctattta     3420

tgtataaata ataacagagc cgacgtgtcc tcgcccagga gggcttccct gtcagcaata     3480

accggcatcc gttttggaac ctgcgtctgg ggctccagtc gctgctcttg ctggcgtcca     3540

tcgccgcctc ggacggccgt gcattttctc gtctcacgca gttcgaggag gaccctagaa     3600

agccaggagc tgtgattgac agtagctgta ggttaccaga cggcaacatt agaaagtgat     3660

tgtaaataac atgcaaccta agtgtaatat atttgttcag ttataagatg attgtttcac     3720

agaagcctta ccactctctg cttcatctaa gaaaaccaat accaaaaacg ccactttaat     3780

gctcagccct gcgttgtgtg ttttcagatg agttactgtt aacaggtagg tttgtgtagg     3840

ccttgctggg cactctgtac aattagttgc ttattacgta tgattactca cagcgatcta     3900

ttgttccata taaccaaaaa gcatggttta ttcattgaaa cacggttgac ctgaactcgt     3960

gccttaggaa ttaatgcccc cttatggaac ctgcctgaat tgcacctgcg ggtggaggct     4020

ccggctgtga agtcactgaa cagaacgtcg ctgatggaga aagggctccc gcagaaggaa     4080

cggcctgtac cgtgcgctcc ggcacaatcg cgtctcttgt gtctcactca cggaaagaaa     4140

caacctgaag gccatcccgt cggtctgcac gtaaccgtga agacgtgtgg ccgcgtccca     4200

cctgcggctg ggtaccctgc acccggcact gtaggagtca cgtgcagcct ttctcagggg     4260

actgtcattg aaaaggaaac gtttgatgtc tgtgtcagct gtctttgtag ttaggaaata     4320

gatccaataa agccgtattt ttttgctgga                                      4350


<210>  1905
<211>  4138
<212>  DNA
<213>  homo sapiens

<400>  1905
gggggcgcgg ccgcgctcgt ctcgccgggc tgttcgcggg caggccctgc cctgaaggga       60

cgaatcggct tggagcgcgg gaggtggagt cggccccggc ggtcgctccc tggacccaac      120

ccgaggctga cccaggcccc tgcccatgcg gggcgcccct ggctcggaag agtcccccgg      180

gccgggagca gctccaggca gcggccccgg aggaagagga agaagggaca gtgctcagct      240

tgggggaccc ggaccctcgc cgcggcattt ggagccgggg gcagtcccga actctgtgct      300

tggcaccgcc gctccgagta gggcagcgcc tgccgggacc ctgacccgga ccccctgcgc      360

ctcgtaggcg gcggcgccgc cgcgccaccc tgttcttccg tgtctccctc tgcctggcgg      420

cagtcacggc caagagagta ttatgaggga ggccgaggac ttcatgctcc ggacagagaa      480

acggcgctgg gattagggat tgccacttct gagaggatgc tgggaatctg cagggggaga      540

cggaaattct tggctgcctc gttgagtctt ctctgcatcc cagccatcac ctggatttac      600

ctgttttctg ggagcttcga agatggaaag cccgtgtctc tgtcaccgct ggagtcccag      660

gcacacagcc ccaggtacac ggcctccagc cagcgggagc gcgagagcct ggaggtgcgc      720

atgcgcgagg tggaggagga gaaccgcgcc ctccgcaggc agctcagcct ggcccagggc      780

cgagccccat cccatcgccg aggcaaccac tccaagacct actccatgga ggagggcact      840

ggagacagcg agaaccttcg ggctggcatc gtggcaggca acagctccga gtgtgggcag      900

cagccggtcg tggagaaatg cgagacaatc cacgttgcta ttgtctgcgc cggatacaat      960

gccagccggg atgtcgtcac cctggtcaaa tccgtcctgt tccatagacg gaaccctctg     1020

cacttccacc ttattgctga ctccattgcg gagcagatcc tggccacgct cttccagacc     1080

tggatggtgc ccgctgtgcg tgtggacttc tacaatgcag acgagctcaa gtctgaagtt     1140

tcctggatcc ccaataaaca ttactctggg atttatggtc tgatgaagct tgtcctgacc     1200

aagactcttc ctgccaacct ggagagagtc atcgtccttg acacggatat cacctttgcc     1260

actgacattg cagagctgtg ggctgtgttc cacaagttca aaggtcagca agtcctgggc     1320

ttggtggaga accagagtga ctggtacctt ggaaacctgt ggaaaaatca ccgcccatgg     1380

ccagcccttg gaagaggcta caacacaggg gtgatcctgt tacttctgga taagctgcgg     1440

aagatgaaat gggagcagat gtggaggctg accgcagaga gggagctcat gggcatgctc     1500

tctacatcct tagctgacca ggatattttc aatgccgtca tcaaacaaaa ccccttcctt     1560

gtgtaccagc tcccctgctt ctggaatgtg cagctgtcag accacacccg ctccgagcag     1620

tgctacagag acgtgtctga tctaaaggtc attcactgga actcccccaa gaagctccgg     1680

gtgaagaaca agcatgtgga gttttttcgc aacctctacc tgaccttcct ggagtatgac     1740

ggcaatcttc tgaggcggga actgtttggc tgccccagtg aggctgatgt caacagtgaa     1800

aacctccaga agcagctgtc tgagctggac gaggacgacc tgtgctatga gttccggcga     1860

gagcgcttca ctgtccaccg cacccacctg tacttcctgc actacgagta tgagcctgca     1920

gcagacagca cggacgtcac cctggtcgct cagctgtcca tggacaggct ccagatgctg     1980

gaggccatct gcaagcactg ggaggggccc atcagcctgg ccctctacct gtcagacgcc     2040

gaggcccagc agttcctccg ctacgcacag ggctctgagg tgcttatgag ccgccacaac     2100

gtgggctacc acatcgtgta caaggagggc cagttctacc ccgtgaacct gctgcgcaac     2160

gtggccatga agcacatcag cactccctac atgttcctgt ctgacattga cttcctgccc     2220

atgtatgggc tctatgagta cctcaggaag tctgtcatcc agctcgatct tgccaacacc     2280

aagaaagcaa tgattgtccc cgcgttcgag acactgcgct accggctgtc cttccccaag     2340

tcaaaagcgg agttgctgtc aatgctggac atggggaccc tcttcacatt caggtaccac     2400

gtctggacga aaggccacgc acccacaaac ttcgccaagt ggcggaccgc caccacgcct     2460

taccgggttg agtgggaggc cgattttgag ccgtatgttg ttgtgagacg tgactgcccg     2520

gagtacgacc ggaggtttgt aggctttggc tggaacaaag tggctcatat catggagctg     2580

gatgtgcagg agtatgagtt cattgtgctg cccaacgcct acatgatcca catgcctcat     2640

gcccccagct tcgacattac caagttccgt tccaacaagc aataccgcat ctgtctcaaa     2700

accctcaagg aagagtttca gcaggacatg tcccgccgct acggctttgc tgccctgaaa     2760

tatctcacag ccgagaacaa cagctagcac caagaagccc accactaggg ggagacatgc     2820

tgtaggggaa gtgccactcg ctgtttgggg cccggccttc aaattcaaaa ttgagccatg     2880

ctttttcggt ttgtttttat ttatctcttt ggcccagcca agctgccctc actacagaga     2940

ccttggacaa ggatccagcc agtccctctc tgccccacaa ccctgcattc ccagaggtta     3000

gctatgcagc ccacctagat gagtctcttc aagaatggga aatcaagggg tgacagggag     3060

taaaagggtt atcatcttac tgcaaagcca caagatcagg gcagggcttt aggatgttct     3120

ggatgctttt taataattat gcttcccatc ataactgggg agaaagggaa gtcagggttc     3180

taggggttat tcgtcccagg aaatagaagt gaaattgtct ttattaagtg aaaactttcc     3240

cctttgccct gcaatgtagc tgggcattca aacggagggc aaaccgatga tctaaaccaa     3300

ccacttggaa aaacccaatg gggacattgt aaccagaggg tcctggaggt ggggttgatg     3360

ggtttcctta tccccaaagt cactcctgtt ttgttttgtt tttctttggg ggttttgttt     3420

atttttgggg ctggcaatcc aaaatagaaa atctgatcct ttgaggctct aaaggaaaat     3480

cagctgcctc taccaaccac cctctatcag cagtggccca ggaaggaggt caagcatctt     3540

cggccgatat ttaaacatgg gcagcttcct tcaggatgat caccgaggct cccgtgactt     3600

tgaactccct actctccaga atccaggggc tatagcgatg gggactgcgg aattacgagg     3660

gctggctgtt ttacaccggt cacattttct attggcagtg actgattcat gggaaagggc     3720

tttgaaggaa ctacttcagt gcacacacaa ggtacgaacc tctcaggcct ttcgaagaac     3780

tttcataatt catgaaagcc cagttctgaa gattcacgta tccatctgga gacctacagg     3840

aagaaagtga ttgggttcct ctggttcttg cctgcttcac tgtggatggg aagaggtgac     3900

aacctcagtc tccctttggg acctgtccaa gggtaggcaa ccaccttcac cttcacacag     3960

attgaggaga cactggactt tttacccatt ttctttaatc ttcaatatta atattgtgtt     4020

tacattgatg agaacaagag ttaatgccct accctctgct gggctgtttg tattgagttg     4080

caatgtgacc agcgaaagct gcatttaata aatgaaagta cagactgttt cttcccca       4138


<210>  1906
<211>  4138
<212>  DNA
<213>  homo sapiens

<400>  1906
gggggcgcgg ccgcgctcgt ctcgccgggc tgttcgcggg caggccctgc cctgaaggga       60

cgaatcggct tggagcgcgg gaggtggagt cggccccggc ggtcgctccc tggacccaac      120

ccgaggctga cccaggcccc tgcccatgcg gggcgcccct ggctcggaag agtcccccgg      180

gccgggagca gctccaggca gcggccccgg aggaagagga agaagggaca gtgctcagct      240

tgggggaccc ggaccctcgc cgcggcattt ggagccgggg gcagtcccga actctgtgct      300

tggcaccgcc gctccgagta gggcagcgcc tgccgggacc ctgacccgga ccccctgcgc      360

ctcgtaggcg gcggcgccgc cgcgccaccc tgttcttccg tgtctccctc tgcctggcgg      420

cagtcacggc caagagagta ttatgaggga ggccgaggac ttcatgctcc ggacagagaa      480

acggcgctgg gattagggat tgccacttct gagaggatgc tgggaatctg cagggggaga      540

cggaaattct tggctgcctc gttgagtctt ctctgcatcc cagccatcac ctggatttac      600

ctgttttctg ggagcttcga agatggaaag cccgtgtctc tgtcaccgct ggagtcccag      660

gcacacagcc ccaggtacac ggcctccagc cagcgggagc gcgagagcct ggaggtgcgc      720

atgcgcgagg tggaggagga gaaccgcgcc ctccgcaggc agctcagcct ggcccagggc      780

cgagccccat cccatcgccg aggcaaccac tccaagacct actccatgga ggagggcact      840

ggagacagcg agaaccttcg ggctggcatc gtggcaggca acagctccga gtgtgggcag      900

cagccggtcg tggagaaatg cgagacaatc cacgttgcta ttgtctgcgc cggatacaat      960

gccagccggg atgtcgtcac cctggtcaaa tccgtcctgt tccatagacg gaaccctctg     1020

cacttccacc ttattgctga ctccattgcg gagcagatcc tggccacgct cttccagacc     1080

tggatggtgc ccgctgtgcg tgtggacttc tacaatgcag acgagctcaa gtctgaagtt     1140

tcctggatcc ccaataaaca ttactctggg atttatggtc tgatgaagct tgtcctgacc     1200

aagactcttc ctgccaacct ggagagagtc atcgtccttg acacggatat cacctttgcc     1260

actgacattg cagagctgtg ggctgtgttc cacaagttca aaggtcagca agtcctgggc     1320

ttggtggaga accagagtga ctggtacctt ggaaacctgt ggaaaaatca ccgcccatgg     1380

ccagcccttg gaagaggcta caacacaggg gtgatcctgt tacttctgga taagctgcgg     1440

aagatgaaat gggagcagat gtggaggctg accgcagaga gggagctcat gggcatgctc     1500

tctacatcct tagctgacca ggatattttc aatgccgtca tcaaacaaaa ccccttcctt     1560

gtgtaccagc tcccctgctt ctggaatgtg cagctgtcag accacacccg ctccgagcag     1620

tgctacagag acgtgtctga tctaaaggtc attcactgga actcccccaa gaagctccgg     1680

gtgaagaaca agcatgtgga gttttttcgc aacctctacc tgaccttcct ggagtatgac     1740

ggcaatcttc tgaggcggga actgtttggc tgccccagtg aggctgatgt caacagtgaa     1800

aacctccaga agcagctgtc tgagctggac gaggacgacc tgtgctatga gttccggcga     1860

gagcgcttca ctgtccaccg cacccacctg tacttcctgc actacgagta tgagcctgca     1920

gcagacagca cggacgtcac cctggtcgct cagctgtcca tggacaggct ccagatgctg     1980

gaggccatct gcaagcactg ggaggggccc atcagcctgg ccctctacct gtcagacgcc     2040

gaggcccagc agttcctccg ctacgcacag ggctctgagg tgcttatgag ccgccacaac     2100

gtgggctacc acatcgtgta caaggagggc cagttctacc ccgtgaacct gctgcgcaac     2160

gtggccatga agcacatcag cactccctac atgttcctgt ctgacattga cttcctgccc     2220

atgtatgggc tctatgagta cctcaggaag tctgtcatcc agctcgatct tgccaacacc     2280

aagaaagcaa tgattgtccc cgcgttcgag acactgcgct accggctgtc cttccccaag     2340

tcaaaagcgg agttgctgtc aatgctggac atggggaccc tcttcacatt caggtaccac     2400

gtctggacga aaggccacgc acccacaaac ttcgccaagt ggcggaccgc caccacgcct     2460

taccgggttg agtgggaggc cgattttgag ccgtatgttg ttgtgagacg tgactgcccg     2520

gagtacgacc ggaggtttgt aggctttggc tggaacaaag tggctcatat catggagctg     2580

gatgtgcagg agtatgagtt cattgtgctg cccaacgcct acatgatcca catgcctcat     2640

gcccccagct tcgacattac caagttccgt tccaacaagc aataccgcat ctgtctcaaa     2700

accctcaagg aagagtttca gcaggacatg tcccgccgct acggctttgc tgccctgaaa     2760

tatctcacag ccgagaacaa cagctagcac caagaagccc accactaggg ggagacatgc     2820

tgtaggggaa gtgccactcg ctgtttgggg cccggccttc aaattcaaaa ttgagccatg     2880

ctttttcggt ttgtttttat ttatctcttt ggcccagcca agctgccctc actacagaga     2940

ccttggacaa ggatccagcc agtccctctc tgccccacaa ccctgcattc ccagaggtta     3000

gctatgcagc ccacctagat gagtctcttc aagaatggga aatcaagggg tgacagggag     3060

taaaagggtt atcatcttac tgcaaagcca caagatcagg gcagggcttt aggatgttct     3120

ggatgctttt taataattat gcttcccatc ataactgggg agaaagggaa gtcagggttc     3180

taggggttat tcgtcccagg aaatagaagt gaaattgtct ttattaagtg aaaactttcc     3240

cctttgccct gcaatgtagc tgggcattca aacggagggc aaaccgatga tctaaaccaa     3300

ccacttggaa aaacccaatg gggacattgt aaccagaggg tcctggaggt ggggttgatg     3360

ggtttcctta tccccaaagt cactcctgtt ttgttttgtt tttctttggg ggttttgttt     3420

atttttgggg ctggcaatcc aaaatagaaa atctgatcct ttgaggctct aaaggaaaat     3480

cagctgcctc taccaaccac cctctatcag cagtggccca ggaaggaggt caagcatctt     3540

cggccgatat ttaaacatgg gcagcttcct tcaggatgat caccgaggct cccgtgactt     3600

tgaactccct actctccaga atccaggggc tatagcgatg gggactgcgg aattacgagg     3660

gctggctgtt ttacaccggt cacattttct attggcagtg actgattcat gggaaagggc     3720

tttgaaggaa ctacttcagt gcacacacaa ggtacgaacc tctcaggcct ttcgaagaac     3780

tttcataatt catgaaagcc cagttctgaa gattcacgta tccatctgga gacctacagg     3840

aagaaagtga ttgggttcct ctggttcttg cctgcttcac tgtggatggg aagaggtgac     3900

aacctcagtc tccctttggg acctgtccaa gggtaggcaa ccaccttcac cttcacacag     3960

attgaggaga cactggactt tttacccatt ttctttaatc ttcaatatta atattgtgtt     4020

tacattgatg agaacaagag ttaatgccct accctctgct gggctgtttg tattgagttg     4080

caatgtgacc agcgaaagct gcatttaata aatgaaagta cagactgttt cttcccca       4138


<210>  1907
<211>  10370
<212>  DNA
<213>  homo sapiens

<400>  1907
gcgcggggcc gcggcggagg ctgggccggg cgggcggcag aagatggcga gggtgtgtag       60

gcggcagcaa tgctccgttg agagacgcgg ctttcggcaa gaactggatt cgtggcgcca      120

caagctcatt cactgtgtag gtcccgtttc cctctgtgcg gcggccggcg ggaccataag      180

ggcttaactc atatatttaa cccccctcca aaaaggtttg aaagtattct tgaagggctg      240

tttggacctg cattattaaa agatctcagt ttatttaaag actgtgaacc tgaaagcatt      300

tctgattgga cttttgatga aaactgttta ttctgttgct tgagaagaga taaagtaaag      360

ggacacttag tcggtctgga tgaaccagct tcgggagctg ggcaagaagc tctgcttaaa      420

caagagcaag caaaaatcat tcgattcgag agacaagcag aagaattcct caatgcagtc      480

ttttatagaa aagacagtcc ctgggtctcc gaccccaata ttcccctagt ggcccgtgag      540

atcatgcagc gaatgatcca acaatttgct gctgaatata cctcaaaaaa tagctctact      600

caggacccca gccagcccaa tagcacaaag aaccaaagcc tgccgaaagc atctccagtc      660

accacctctc ccacggctgc aactactcag aaccctgtgc tcagcaaact tctcatggct      720

gaccaagact cacctctgga ccttactgtc agaaagtctc agtcagaacc tagcgaacaa      780

gacggtgtac ttgatctgtc cactaagaaa agtccatgtg ctggcagcac ttccctgagc      840

cactctccag gctgctccag tactcaaggg aacgggcgac ctgggagacc cagccagtac      900

cgcccagacg gacttcggag tggtgatggg gtacctccaa gaagcttaca ggatggaacc      960

agggaaggtt ttggacactc cacatcactc aaagttccac tggctcgatc cctgcagatt     1020

agtgaagaac tactgagcag aaaccaattg tccacagctg ccagccttgg gccatctgga     1080

ttacagaatc atggacaaca cttaatatta tccagggaag cctcttgggc aaaaccacat     1140

tacgagttca acctcagccg tatgaagttc aggggaaatg gtgcactcag caacatcagt     1200

gaccttcctt ttcttgcaga aaactctgcc tttccaaaaa tggcacttca agcaaaacaa     1260

gatggaaaaa aggatgtgag ccattcatct cctgtagatt taaagatacc acaagttcga     1320

ggaatggatc tttcttggga gtctcgcact ggtgatcagt acagctatag ctctttggta     1380

atgggttcac aaacggagag cgcgcttagt aaaaaattaa gggctattct tccaaaacaa     1440

agtagaaaaa gcatgttaga tgctggaccc gattcttggg gctcagatgc tgagcagtct     1500

acctctggac agccatatcc cacatcggat caagaaggag accctggctc caagcagcct     1560

cggaagaaaa gagggcgtta cagacagtac aacagtgaga tactggagga agcaatctca     1620

gtggttatga gtggaaaaat gagtgtttcc aaagctcaga gtatttatgg gattccccac     1680

agtacactgg agtacaaagt aaaggagagg ctgggcactt tgaaaaaccc tccaaagaaa     1740

aagatgaaat taatgaggtc ggaggggcca gatgtttctg taaagattga attagatccc     1800

cagggagagg cagcacaaag tgcaaatgaa tcaaaaaacg agtaggaata ctgtagagtg     1860

ccaattactg tacaaactgg gtgagcacta ctgcatcatt gttcagctat cattgcttgc     1920

acgtaatttc atttactgtg acacttgctt ctttgcagat tttgcattga cttgtgtgta     1980

cagagatgaa atgtgcattc tgaatgttgc atattttaaa tttttcatgt gcagtatggc     2040

tcggaatatg tttggccttt tgcatgtttc tctacaaaag agaattgagt tacctcacag     2100

agaacagata catggaagtg gactccttgc ctgtagagcc tgcatgcttt tttgtttttt     2160

tttgttgttg ttgttttttc ttaagttata tttgttttta ctttttaaaa aagaagagga     2220

aacaaagccc ccttttagaa actacgtctg tcatactggg agctttatca ctgcaaattg     2280

gaaagccatc ttatacaaaa ttattcacat ttttcatcta cgattcaact aatcgaagga     2340

ttaaactaaa gaaaaaacta agaagaacaa tgaacctttg actttgagaa atttggttat     2400

tcactgacat aattattggg tcatttatag ttacatttta taattttctt ctcactatta     2460

aatttattta aattagcaag ctattagtgc tcacccagag gggaaggtgg tggaaaatgt     2520

gcacacacta ccttcagaaa tgcttcagtt aattactttg aacactacct ttgctgtaat     2580

ttcatttgag attttctaag ggtagaattt ggtctcacca acaagtgagg atatagcctt     2640

atctcatgga ggacgagctc cgtatttact caggagcagt cagggtacat tacataaaac     2700

aatggaggat gcctcatttt agcaaactag gtttctttgt attcttcagt ccttttacag     2760

aattgatgtg ctaactgaat atcattgcag caactagact aagatattca agatctcttt     2820

attggggatg ggagaaatag ggaaagaaat gtgtataagt aattatgata ttgcaaaagt     2880

gatacttaga ttttacagcc tcagtagtct gcccagtgtc cacattaatg aaggatccat     2940

gtttgtagtg agagaaaaaa accccaaggt aacccgatat gatttaggat gcatatcagt     3000

tctaacaatt caatcagaag tcaagctcat tggaattcct tttttaactg atccaaatac     3060

tagtagaagg gggagggaga ggtgttgggt ttttttttta agtttttatt taattttgtt     3120

ggttagaatt tttttctgtt tttggcatcc tacataatac cccccttctt gactttttct     3180

gataattagc tgatattcat ggttgtttag cacacagttc aggacctttg agatcatgtt     3240

tgtataagca ctccttgaag aatatctaag ctttttctga gatgggcttt taaaattata     3300

ataagggaag tttattttct gcggtttttg caagaataag caaagcccat ggaatttaat     3360

ttttcattgt gatcagatta aaattactat ttgtgcaaaa caaattccac accacatgta     3420

ctgtatattc taatctgctg agaaaggtgg tcaggccctt ctaaatgctt aaccaaaaac     3480

aaacattatt ggagtttcag tgtaaaataa aattaaaatt ggagggttgg ttagattgat     3540

ttcagatgga tactaacagt ttgaggggag gtccagatat ttccaaggca taaattcttg     3600

cctggaaact ttggagcaat taattaaatt aggttaagtt ttccctcagc aacctgtgtg     3660

ttcaaaggtt aggcacacca ttgctgttac taaaatacat gcactgctca ttcttgacat     3720

agcttgggtg tgggttcctc ttgttttggt tattttgtgt agcagtttaa tcagtggata     3780

actgagcctg tttcctctta gctttctaga cttcttaaca gaaaaaacag tttgggttca     3840

atagcatttt atgattctac aatattttgt cacctagctg gaagttgcaa taaaaattcc     3900

ttatgaaata tatggttttc atctgtaatt gaaggaaatc atagaaagtt tgctgaaagc     3960

aaagggctaa gcttatgaag gaatgcctcc tttgttacac actcaagaat ttgtcagcac     4020

acaattaatt gcagccatag tacctttttg cgtaatgttt gggatattca gtagcccagg     4080

attgctacaa aaaggtcctt tgagaaaatt aatttgtgct tgcttttatc ccctctcaga     4140

aagacatcac taaaggccca ttaaaaatct ggccctaaaa gttcaacttt tgtagagttt     4200

attgttcaga gaggtttaat cctatgtggt agtctatata agtgatgtat gagttgagtt     4260

atgtaaattt tgtcattgta gtgtacatgg agtgatcatt ttactaacat aaatattttc     4320

tatgtgtgtt tcagtggatg acaatcgagc agcagaagaa tggtgtgcct accctttaat     4380

gctgcagttt aagagaactt gtattgtgtc atttcagatt gtaggctgag agttgtaaat     4440

agtgaaaatt tgagtacttc tattatttgt tttggttaga aagtgaattt aaaaaacaaa     4500

ccaaactcta aactttctca gattaaaagt cctgagacct gaagattgta atattcatgt     4560

ctgtgaagct tttaaacatt acacttgaga tcagtcatga cttgatattc aggtaaattt     4620

tcttttccaa gaagcttttg aataagcata tttcctccaa aggtctctct ctttctctct     4680

ctttttttga gtgtagatta ttttaaagca ctaattgcat tacattggta actgcaatat     4740

aaaatagcca ttattgtttt gtgaagcatg gttgaaatta gctagtggtc ccttttgaat     4800

ttcatgagcc tctcaaaaaa gaaaaactta aaaaaaaaaa aaaaaaaaaa caaaaagctg     4860

ctggaatatt tcaaaagata tatattttac cttattatag gttttgtaaa gttagtttgt     4920

aatattcagg tgcactttta atgttaaatt ttgtgttcag agttccatta taccatgtat     4980

ttctcggagg tggctcatca cacggctggt ggcagtcttg gtgccgcagt gattccttaa     5040

tatttgattt ctctcttgat ttgccactat tctgtattgg cactttcagt gtagatattc     5100

tagtttgggg atgtcctcac aatgtgtaat agagattggt ctattagcat gcttaatttc     5160

tgctaatcag agttttgcat ggcccaaaca acagttgacc atttttatgg tatgggaaag     5220

tgtagttcac aactgtcttt gtcacgaaag ccgtttttcc tcacattttc cagtaggcag     5280

ataacattac ttaaattatt aatatataac actcttggaa ctattgatag gaaataatgt     5340

atttaaaata attttttgca ttttcagaga ccttgatgtt atagggtaga taagctatgg     5400

cactataaaa tcaaaaacac taattctgtg gaaggatatc tagttggtat ttttatcttt     5460

agctttctca tttctgagac agcatagtca tccagcttga tggtaatgta gtatattact     5520

ttgttcagtg ggcttataag tgactctgaa ttatgtttgt gatgagctat acactttttt     5580

tctgttcccc aaataccatg aaggacaagg tcactctttc aggaaaaata atttatattt     5640

gtgtataata ctttttaata ttaagtttgt tgttctgaag tttagatgtt gcttgataaa     5700

cctttgctgc agcagatcat gaatatgagt aaggctttgt gtgataatag gggtccttat     5760

gtgaagttaa ttactgttca gttctggtga gcaagctcaa caagtgtgaa gtgtgtatta     5820

gctttatttg gtacactttt actttacaat atcgaagtgc ttttagaact ctggttatct     5880

tatataaacc attacctcaa ccaattggca tttcttttcc ccaacattta ccttagctat     5940

aatatgagct atgtgggatc agatggtaaa actataaaag gcacaatgag aagtttagtt     6000

cccaagtttt ggagagaact ctaaattaga ctaaaaacaa ctacctgtta acaccaatat     6060

cataactacc ttctgtcgtt aggcagtaca tagcaacctt tgagctgcta gtgagctatc     6120

tgttctcccc ctacccccaa gtaagcacac agtgccaggc ctggttctaa gcctttgtga     6180

ttctcttaca tctcattgac ccataatagt gaagcatgga ttcatttatt ttcataagac     6240

aaattgagtc agctcgatgt cagaagttga aaatattttg agtagtttaa cagttatatg     6300

agagattggc atcattttct ttaacagctt ttatctttgt agatttcctt ttgagacatg     6360

tatttttgct tttataatcc tttcattaaa tgccagaggt tgttttcata ttaatcactc     6420

ttttctgtat attcaggttg ctgtcattgg tgatagaata tggcaataga cagaattgtg     6480

ctccacttta tgttttttag gagatattga aagttatagg ttaaattttg gccttcttga     6540

agatatcaaa gattgttttc cttgttacct ttaattagaa tttggtcttc attaatgctt     6600

tggtcaggct agcattacta aaaacttgat ggcttcagca gaacagcccg tttaggagac     6660

tattaagcta tctagggatt ttttttcaaa ttaattgctt tcaaaatctg aaaaggaaaa     6720

aagtataatt gtggtacaaa gaagacagat ctccaggctc tttcttctca gtttattttg     6780

gtttaattct gtactggaga cttgaatagg atttgtgaac atggtgatgg aaagaaaaat     6840

agaggacatt atttgtgtac cctcattcct gaataatctt gcagtcacct tttaaagaag     6900

cagacattag ccctgtaaca caacactgta gctataaact ctaagtgtta ggaaggagat     6960

tggggtgggg agggtggagt aggatggaaa aagcatgtag acttctgaga agaggctaaa     7020

aattctgccc tataatacta aaaatgagtc acaagataat gtggtgaagt taggccatct     7080

tgatttgata gaaaaatctt ttacattgtt taaaaatgag aatcgaggct aattaatgtt     7140

gatttgacaa tagaacatga gctaattctg caaccgtttg gggggtaatt ttatggtttc     7200

cagttcattt agagctgtat caagaaaagc taaaaagcaa gcacttttag ttaatcatag     7260

atttattgga tatagcaaat attattataa tatttaatct ctattatttg aatgtggaaa     7320

tgaactcttt taccccatct tgaactgtca ttgaacatgc tcaagatgat caacactgga     7380

aatgacccta cacacatacc aaaaaaatct aaagcagtaa gacatatttg aagatccata     7440

cctcttaaac tttttagatt tgtcttggga aagaatttat gaacctgtaa ccagtattag     7500

tgcagtcttg ggttccttgt tctgcataat tgcacccttt ctcaggtatg tcctgacaac     7560

ataaatttta aaataatctc attagagatt agattctcag tggatagtgt gtaaggggac     7620

taggggtggg gggttggggg tagttggaca caggacactg acacagtaga gcagggattt     7680

ttaacagtca atagccaaat agaatttcaa tctagaatat ttttaccccc tcagaatgag     7740

tgaaacaact tctattattt ggtgtacccg gtgctacact cctaaaagtc tttttttttt     7800

ttcatccagg tgacgttttt tatttttcct gcttggtggt ggaaggttat atagtaaact     7860

tcactgtcat taagaaagcg cttgtccaaa atgtttaaag tactagaaaa gggataattc     7920

agcacttttt ctgttacaac actaaagtct taatttatct tcagagtctt aggtactgta     7980

agtttttgga tgattattta aaaatataaa acatactaca taatatgggg tcagatcaca     8040

tttatataaa taattcttat tttaaaaaag acaataacat tttgtacctt tctagcaatt     8100

ccaagtgatt gcctcatttt ctcttgttaa gcatttcaag cttaagaatt tggaatttga     8160

gagaaggtga gggggaaaat tccctaaaat aaaaatttgt ttcaaaccat tttagaaaaa     8220

taaatcacta ggaaaatagg tagggattct ctcccccttt aagtcttcag ggaatgagca     8280

gtatttagaa tctttggctg aaattcaagc ctttttactt tgtaaatttt taatattaat     8340

tcactgacat gctttttaca ccagaggact gaaaatggat cttaatgttt ttaagttgtg     8400

gaagggtata tttctaaaat gaggggggat gattaactag gttagtatta ccagcattag     8460

taagtttaag gaattttagt atgtaatagc aaagtgtttg attaaaagtc taatcctata     8520

ttactagtca aaattagtta cattctgatc taggaaagat aatagtcatt ggatattgat     8580

atgctgtgct gtcagaaaac cagactaaga tagaaacctt tatctgactc ccacatgttg     8640

cttgttgtga tgggatgtat actttacagc agcttattgc tgctttgaaa aaaaatgtat     8700

aaactataca tttggagtgt ttgcatataa ttctttataa cctccactta aagctgtcag     8760

acattggtat tttatcagtc cacattgttg aataaaacta atgttcttag gaatccagct     8820

tgtacacact gtttaaaaac cctcagggac agtttacaca ctcttctcac tcaattcagg     8880

tactttgatg ctattcttaa acctaacagt gacttgtatt tttctgtttt gcttttattt     8940

caacgtgctg gtagcacatc tgatgaatgt caacttaaaa aactcagttc aggtatccag     9000

gtataactca gccaaacaga ttttaaagct gcatataact ctccagcaca tggtgcctca     9060

cactcttata gtggcattct atatattcag ttattactac tgagcagata atatgggggt     9120

tcctgttaac agtgtatttt ttaaaaaaag cgcataaatg tatagccagc acactacaca     9180

cacacacaca aacatgcaca gttaaactat atatttttaa atgccactaa tagccagcac     9240

aactaaaaca aaagacattc ctaactgctc tgtaagctgt taacagatgc agttccttct     9300

tgatgtggct cttgcttctt cacgataact actactaaat tcaagcactg gtccttgggt     9360

gtctgacctc tacattctag tttatgcaat gtctttagag aattttgtgc actggccact     9420

gtgatggaac cattgggcca ggagtgcttt gagtttatca gtagtgattc tgccaaagtt     9480

ggtgttgtaa catgagtatg taaaatgtca aaaaaattag cagaggtcta ggtctgcata     9540

tcagcagaca gttttgtccg tgtattttgt agccttgaag ttctcagtga caagtttttt     9600

ctgatgcgaa gttctaattc cagtgtttta gtcctttgca tctttaatgt taagacttgc     9660

ctctttaaaa ttgcttttgt tttctgcagt actatctgtg gttaacaaaa tagattattt     9720

ctctgcttta atatttgata tcttacatct aaaataaatt ctctccacat ataaaaccca     9780

tagcctttgg agatatggaa aatggtatct ttcagatttc tagaagttca agtgtcatac     9840

aacaaaacag gaaccccctt tactcttatg gacctcattt caatatactg tttacagttt     9900

gatggaattg tataatttaa tatttctctt gtactgtagt ttatatttat ttacagattt     9960

ttttgtactg tgtgatttga actttttgtt ccttgctatg atcaatgttt atgtagtaga    10020

gcacttatga tcacaaatta agttttttgg tttgattgca ctacattaaa ttttttaatg    10080

cagttctgat ttttgactgg actaaaactg tgtcttaatg tatgtgatga gtacttaaaa    10140

ttttaatcca tgtggtcccc cccctttttt ttttttttgc attgtatgtc aaaagcgctt    10200

gttctttcgt gcatgtgtaa gatttaatgg ttccattgta ttatttgacc atgacatttt    10260

ggagaaacat tcccagctgt aatgttgtgt atggtagttc tcactggatg ctagagtttt    10320

caaaaccact attcttctaa taaattttgt tgtgaaaaac tgttaaaaaa               10370


<210>  1908
<211>  7793
<212>  DNA
<213>  homo sapiens

<400>  1908
gcgcggggcc gcggcggagg ctgggccggg cgggcggcag aagatggcga gggtgtgtag       60

gcggcagcaa tgctccgttg agagacgcgg ctttcggcaa gaactggatt cgtggcgcca      120

caagctcatt cactgtgtag gtcccgtttc cctctgtgcg gcggccggcg ggaccataag      180

ggcttaactc atatatttaa cccccctcca aaaaggtttg aaagtattct tgaagggctg      240

tttggacctg cattattaaa agatctcagt ttatttaaag actgtgaacc tgaaagcatt      300

tctgattgga cttttgatga aaactgttta ttctgttgct tgagaagaga taaagtaaag      360

ggacacttag tcggtctgga tgaaccagct tcgggagctg ggcaagaagc tctgcttaaa      420

caagagcaag caaaaatcat tcgattcgag agacaagcag aagaattcct caatgcagtc      480

ttttatagaa aagacagtcc ctgggtctcc gaccccaata ttcccctagt ggcccgtgag      540

atcatgcagc gaatgatcca acaatttgct gctgaatata cctcaaaaaa tagctctact      600

caggacccca gccagcccaa tagcacaaag aaccaaagcc tgccgaaagc atctccagtc      660

accacctctc ccacggctgc aactactcag aaccctgtgc tcagcaaact tctcatggct      720

gaccaagact cacctctgga ccttactgtc agaaagtctc agtcagaacc tagcgaacaa      780

gacggtgtac ttgatctgtc cactaagaaa agtccatgtg ctggcagcac ttccctgagc      840

cactctccag gctgctccag tactcaaggg aacgggcgac ctgggagacc cagccagtac      900

cgcccagacg gacttcggag tggtgatggg gtacctccaa gaagcttaca ggatggaacc      960

agggaaggtt ttggacactc cacatcactc aaagttccac tggctcgatc cctgcagatt     1020

agtgaagaac tactgagcag aaaccaattg tccacagctg ccagccttgg gccatctgga     1080

ttacagaatc atggacaaca cttaatatta tccagggaag cctcttgggc aaaaccacat     1140

tacgagttca acctcagccg tatgaagttc aggggaaatg gtgcactcag caacatcagt     1200

gaccttcctt ttcttgcaga aaactctgcc tttccaaaaa tggcacttca agcaaaacaa     1260

gatggaaaaa aggatgtgag ccattcatct cctgtagatt taaagatacc acaagttcga     1320

ggaatggatc tttcttggga gtctcgcact ggtgatcagt acagctatag ctctttggta     1380

atgggttcac aaacggagag cgcgcttagt aaaaaattaa gggctattct tccaaaacaa     1440

agtagaaaaa gcatgttaga tgctggaccc gattcttggg gctcagatgc tgagcagtct     1500

acctctggac agccatatcc cacatcggat caagaaggag accctggctc caagcagcct     1560

cggaagaaaa gagggcgtta cagacagtac aacagtgaga tactggagga agcaatctca     1620

gtggttatga gtggaaaaat gagtgtttcc aaagctcaga gtatttatgg gattccccac     1680

agtacactgg agtacaaagt aaaggagagg ctgggcactt tgaaaaaccc tccaaagaaa     1740

aagatgaaat taatgagtgg atgacaatcg agcagcagaa gaatggtgtg cctacccttt     1800

aatgctgcag tttaagagaa cttgtattgt gtcatttcag attgtaggct gagagttgta     1860

aatagtgaaa atttgagtac ttctattatt tgttttggtt agaaagtgaa tttaaaaaac     1920

aaaccaaact ctaaactttc tcagattaaa agtcctgaga cctgaagatt gtaatattca     1980

tgtctgtgaa gcttttaaac attacacttg agatcagtca tgacttgata ttcaggtaaa     2040

ttttcttttc caagaagctt ttgaataagc atatttcctc caaaggtctc tctctttctc     2100

tctctttttt tgagtgtaga ttattttaaa gcactaattg cattacattg gtaactgcaa     2160

tataaaatag ccattattgt tttgtgaagc atggttgaaa ttagctagtg gtcccttttg     2220

aatttcatga gcctctcaaa aaagaaaaac ttaaaaaaaa aaaaaaaaaa aaacaaaaag     2280

ctgctggaat atttcaaaag atatatattt taccttatta taggttttgt aaagttagtt     2340

tgtaatattc aggtgcactt ttaatgttaa attttgtgtt cagagttcca ttataccatg     2400

tatttctcgg aggtggctca tcacacggct ggtggcagtc ttggtgccgc agtgattcct     2460

taatatttga tttctctctt gatttgccac tattctgtat tggcactttc agtgtagata     2520

ttctagtttg gggatgtcct cacaatgtgt aatagagatt ggtctattag catgcttaat     2580

ttctgctaat cagagttttg catggcccaa acaacagttg accattttta tggtatggga     2640

aagtgtagtt cacaactgtc tttgtcacga aagccgtttt tcctcacatt ttccagtagg     2700

cagataacat tacttaaatt attaatatat aacactcttg gaactattga taggaaataa     2760

tgtatttaaa ataatttttt gcattttcag agaccttgat gttatagggt agataagcta     2820

tggcactata aaatcaaaaa cactaattct gtggaaggat atctagttgg tatttttatc     2880

tttagctttc tcatttctga gacagcatag tcatccagct tgatggtaat gtagtatatt     2940

actttgttca gtgggcttat aagtgactct gaattatgtt tgtgatgagc tatacacttt     3000

ttttctgttc cccaaatacc atgaaggaca aggtcactct ttcaggaaaa ataatttata     3060

tttgtgtata atacttttta atattaagtt tgttgttctg aagtttagat gttgcttgat     3120

aaacctttgc tgcagcagat catgaatatg agtaaggctt tgtgtgataa taggggtcct     3180

tatgtgaagt taattactgt tcagttctgg tgagcaagct caacaagtgt gaagtgtgta     3240

ttagctttat ttggtacact tttactttac aatatcgaag tgcttttaga actctggtta     3300

tcttatataa accattacct caaccaattg gcatttcttt tccccaacat ttaccttagc     3360

tataatatga gctatgtggg atcagatggt aaaactataa aaggcacaat gagaagttta     3420

gttcccaagt tttggagaga actctaaatt agactaaaaa caactacctg ttaacaccaa     3480

tatcataact accttctgtc gttaggcagt acatagcaac ctttgagctg ctagtgagct     3540

atctgttctc cccctacccc caagtaagca cacagtgcca ggcctggttc taagcctttg     3600

tgattctctt acatctcatt gacccataat agtgaagcat ggattcattt attttcataa     3660

gacaaattga gtcagctcga tgtcagaagt tgaaaatatt ttgagtagtt taacagttat     3720

atgagagatt ggcatcattt tctttaacag cttttatctt tgtagatttc cttttgagac     3780

atgtattttt gcttttataa tcctttcatt aaatgccaga ggttgttttc atattaatca     3840

ctcttttctg tatattcagg ttgctgtcat tggtgataga atatggcaat agacagaatt     3900

gtgctccact ttatgttttt taggagatat tgaaagttat aggttaaatt ttggccttct     3960

tgaagatatc aaagattgtt ttccttgtta cctttaatta gaatttggtc ttcattaatg     4020

ctttggtcag gctagcatta ctaaaaactt gatggcttca gcagaacagc ccgtttagga     4080

gactattaag ctatctaggg attttttttc aaattaattg ctttcaaaat ctgaaaagga     4140

aaaaagtata attgtggtac aaagaagaca gatctccagg ctctttcttc tcagtttatt     4200

ttggtttaat tctgtactgg agacttgaat aggatttgtg aacatggtga tggaaagaaa     4260

aatagaggac attatttgtg taccctcatt cctgaataat cttgcagtca ccttttaaag     4320

aagcagacat tagccctgta acacaacact gtagctataa actctaagtg ttaggaagga     4380

gattggggtg gggagggtgg agtaggatgg aaaaagcatg tagacttctg agaagaggct     4440

aaaaattctg ccctataata ctaaaaatga gtcacaagat aatgtggtga agttaggcca     4500

tcttgatttg atagaaaaat cttttacatt gtttaaaaat gagaatcgag gctaattaat     4560

gttgatttga caatagaaca tgagctaatt ctgcaaccgt ttggggggta attttatggt     4620

ttccagttca tttagagctg tatcaagaaa agctaaaaag caagcacttt tagttaatca     4680

tagatttatt ggatatagca aatattatta taatatttaa tctctattat ttgaatgtgg     4740

aaatgaactc ttttacccca tcttgaactg tcattgaaca tgctcaagat gatcaacact     4800

ggaaatgacc ctacacacat accaaaaaaa tctaaagcag taagacatat ttgaagatcc     4860

atacctctta aactttttag atttgtcttg ggaaagaatt tatgaacctg taaccagtat     4920

tagtgcagtc ttgggttcct tgttctgcat aattgcaccc tttctcaggt atgtcctgac     4980

aacataaatt ttaaaataat ctcattagag attagattct cagtggatag tgtgtaaggg     5040

gactaggggt ggggggttgg gggtagttgg acacaggaca ctgacacagt agagcaggga     5100

tttttaacag tcaatagcca aatagaattt caatctagaa tatttttacc ccctcagaat     5160

gagtgaaaca acttctatta tttggtgtac ccggtgctac actcctaaaa gtcttttttt     5220

tttttcatcc aggtgacgtt ttttattttt cctgcttggt ggtggaaggt tatatagtaa     5280

acttcactgt cattaagaaa gcgcttgtcc aaaatgttta aagtactaga aaagggataa     5340

ttcagcactt tttctgttac aacactaaag tcttaattta tcttcagagt cttaggtact     5400

gtaagttttt ggatgattat ttaaaaatat aaaacatact acataatatg gggtcagatc     5460

acatttatat aaataattct tattttaaaa aagacaataa cattttgtac ctttctagca     5520

attccaagtg attgcctcat tttctcttgt taagcatttc aagcttaaga atttggaatt     5580

tgagagaagg tgagggggaa aattccctaa aataaaaatt tgtttcaaac cattttagaa     5640

aaataaatca ctaggaaaat aggtagggat tctctccccc tttaagtctt cagggaatga     5700

gcagtattta gaatctttgg ctgaaattca agccttttta ctttgtaaat ttttaatatt     5760

aattcactga catgcttttt acaccagagg actgaaaatg gatcttaatg tttttaagtt     5820

gtggaagggt atatttctaa aatgaggggg gatgattaac taggttagta ttaccagcat     5880

tagtaagttt aaggaatttt agtatgtaat agcaaagtgt ttgattaaaa gtctaatcct     5940

atattactag tcaaaattag ttacattctg atctaggaaa gataatagtc attggatatt     6000

gatatgctgt gctgtcagaa aaccagacta agatagaaac ctttatctga ctcccacatg     6060

ttgcttgttg tgatgggatg tatactttac agcagcttat tgctgctttg aaaaaaaatg     6120

tataaactat acatttggag tgtttgcata taattcttta taacctccac ttaaagctgt     6180

cagacattgg tattttatca gtccacattg ttgaataaaa ctaatgttct taggaatcca     6240

gcttgtacac actgtttaaa aaccctcagg gacagtttac acactcttct cactcaattc     6300

aggtactttg atgctattct taaacctaac agtgacttgt atttttctgt tttgctttta     6360

tttcaacgtg ctggtagcac atctgatgaa tgtcaactta aaaaactcag ttcaggtatc     6420

caggtataac tcagccaaac agattttaaa gctgcatata actctccagc acatggtgcc     6480

tcacactctt atagtggcat tctatatatt cagttattac tactgagcag ataatatggg     6540

ggttcctgtt aacagtgtat tttttaaaaa aagcgcataa atgtatagcc agcacactac     6600

acacacacac acaaacatgc acagttaaac tatatatttt taaatgccac taatagccag     6660

cacaactaaa acaaaagaca ttcctaactg ctctgtaagc tgttaacaga tgcagttcct     6720

tcttgatgtg gctcttgctt cttcacgata actactacta aattcaagca ctggtccttg     6780

ggtgtctgac ctctacattc tagtttatgc aatgtcttta gagaattttg tgcactggcc     6840

actgtgatgg aaccattggg ccaggagtgc tttgagttta tcagtagtga ttctgccaaa     6900

gttggtgttg taacatgagt atgtaaaatg tcaaaaaaat tagcagaggt ctaggtctgc     6960

atatcagcag acagttttgt ccgtgtattt tgtagccttg aagttctcag tgacaagttt     7020

tttctgatgc gaagttctaa ttccagtgtt ttagtccttt gcatctttaa tgttaagact     7080

tgcctcttta aaattgcttt tgttttctgc agtactatct gtggttaaca aaatagatta     7140

tttctctgct ttaatatttg atatcttaca tctaaaataa attctctcca catataaaac     7200

ccatagcctt tggagatatg gaaaatggta tctttcagat ttctagaagt tcaagtgtca     7260

tacaacaaaa caggaacccc ctttactctt atggacctca tttcaatata ctgtttacag     7320

tttgatggaa ttgtataatt taatatttct cttgtactgt agtttatatt tatttacaga     7380

tttttttgta ctgtgtgatt tgaacttttt gttccttgct atgatcaatg tttatgtagt     7440

agagcactta tgatcacaaa ttaagttttt tggtttgatt gcactacatt aaatttttta     7500

atgcagttct gatttttgac tggactaaaa ctgtgtctta atgtatgtga tgagtactta     7560

aaattttaat ccatgtggtc cccccccttt tttttttttt tgcattgtat gtcaaaagcg     7620

cttgttcttt cgtgcatgtg taagatttaa tggttccatt gtattatttg accatgacat     7680

tttggagaaa cattcccagc tgtaatgttg tgtatggtag ttctcactgg atgctagagt     7740

tttcaaaacc actattcttc taataaattt tgttgtgaaa aactgttaaa aaa            7793


<210>  1909
<211>  3373
<212>  DNA
<213>  homo sapiens

<400>  1909
tttaaagaga gaggatcgta ttatagatac cgcgggggca aagctaaaaa aggggggagg       60

ggggaggaaa aaattcaaga agcagaaacc cctcgcggag ttttactgga agaaaaaaac      120

gggtctgaaa gattcctcct cttcatcatc atcaaccatc attcattcac taccttgaca      180

ttccgggctt tgattgacag ctggagtggc aaaaagccat gaaacacgac agttcggtta      240

catgtgggct gctgacgggc cgctcgtaac cttcagttcg ggggcttgac aatttttttc      300

ttctttttct tctttttctt ttctttcttt ttttttccaa ctgaggggaa gagaagagaa      360

agagggggaa aggaggaccg aagaggagga ggaggggagg ggggaggagg aggaggtgga      420

ggaggaggag gaagatcagg aggaggagga agaagaggaa aaaagagaaa aagaagaaat      480

atcacagaaa aaaaaattct tcgttgtcta gactgggctt tttttccccc ctaaaaaata      540

gcatattgga gaattgggag aagtctcttt ggtttggaaa aaaaaaaaag gaatcttcag      600

cctagatcac tttcttatcc ggactgggat attaaatata cgacacatcc aggagtttat      660

tggagcgcag actgatggcg caaaggtacg atgagctgcc ccattacggc gggatggacg      720

gagtaggggt tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg      780

ttcaccacct gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc      840

cgcaccccaa tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg      900

acaaggacgc gatctatggg cacccgttgt ttcctctgtt agctctggtc tttgagaagt      960

gcgagctggc gacctgcact ccccgggaac ctggagtggc tggcggagac gtctgctcct     1020

ccgactcctt caacgaggac atcgcggtct tcgccaagca ggttcgcgcc gaaaagccac     1080

ttttttcctc aaatccagag ctggacaatt tgatgataca agcaatacaa gtactaaggt     1140

ttcatctttt ggagttagaa aaggtccacg aactgtgcga taacttctgc caccgataca     1200

ttagctgttt gaaggggaaa atgcccatcg acctcgtcat tgatgaaaga gacggcagct     1260

ccaagtcaga tcatgaagaa ctttcaggct cctccacaaa tctcgctgac cataaccctt     1320

cttcttggcg agaccacgat gatgcaacct caacccactc agcaggcacc ccagggccct     1380

ccagtggggg ccatgcttcc cagagcggag acaacagcag tgagcaaggg gatggtttag     1440

acaacagtgt agcttcacct ggtacaggtg acgatgatga tccggataag gacaaaaaac     1500

gccagaagaa aagaggcatt ttccccaaag tagcaacaaa tatcatgaga gcatggctct     1560

tccagcatct cacacatccg tacccttccg aagagcagaa gaaacagtta gcgcaagaca     1620

caggacttac aattctccaa gtaaacaact ggtttattaa tgccagaaga agaatagtac     1680

agcccatgat tgaccagtca aatcgagcag gttttcttct tgatccttca gtgagccaag     1740

gagcagcata tagtccagag ggtcagccca tggggagctt tgtgttggat ggtcagcaac     1800

acatggggat ccggcctgca ggacctatga gtggaatggg catgaatatg ggcatggatg     1860

ggcaatggca ctacatgtaa ccttcatcat gtaaagcaat cgcaaagcaa gggggaagtt     1920

tgcagagcat gccaggggac tacgtttctc agggtggtcc tatgggaatg agtatggcac     1980

agccaagtta cactcctccc cagatgaccc cacaccctac tcaattaaga catggacccc     2040

caatgcattc atatttgcca agccatcccc accacccagc catgatgatg cacggaggac     2100

cccctaccca ccctggaatg actatgtcag cacagagccc cacaatgtta aattctgtag     2160

atcccaatgt tggcggacag gttatggaca ttcatgccca atagtataag ggaactcaag     2220

ggaaaaggaa acacacgcaa aaactatttt aagactttct gaactttgac cagatgttga     2280

cacttaatat gaaattccag acagctgtga ttatttttta cttttgtcat ttttcatcaa     2340

gcaacagagg accaatgcaa caagaacaca aatgtgaaat catgggctga ctgagacaat     2400

tctgtccatg taaagatcct ctggaaaaag actccgagag ttataactac tgtagtataa     2460

atataggaac taagttaaac ttgtacattt ctgttgatca cgccgttatg ttgcctcaaa     2520

tagttttaga agagaaaaaa aaatatatcc ttgttttcca cactatgtgt gttgttccca     2580

aaagaatgac tgttttggtt catcagtgaa ttcaccatcc aggagagact gtggtatata     2640

ttttaaacct gttgggccaa tgagaaaaga accacactgg agatcatgat gaacttttgg     2700

ctgaacctca tcactcgaac tccagcttca agaatgtgtt ttcatgcccg gcctttgttc     2760

ctccataaat gtgtccttta gtttcaaaca gatctttata gttcgtgctt cataagccaa     2820

ttcttattat tatttttggg ggactcttct tcaaagagct tgccaatgaa gatttaaaga     2880

cagagcagga gcttcttcca ggagttctga gccttggttg tggacaaaac aatcttaagt     2940

tgggcagctt tcctcaacac aaaaaaaagt tattaatggt cattgaacca taactaggac     3000

tttatcagaa actcaaagct tgggggataa aaaggagcaa gagaatactg taacaaactt     3060

cgtacagagt tcggtctatt aattgtttca tgttagatat tctatgtgtt tacctcaatt     3120

gaaaaaaaaa agaatgtttt tgctagtatc agatctgctg tggaattggt attgtatgtc     3180

catgaattct tcttttctca gcacgtgttc ctcactagaa gaaaatgctg ttacctttaa     3240

gctttgtcaa atttacatta aaatacttgt atgaggactg tgacgttatg ttaaaaaaaa     3300

aaaggtgtta agtcacaaaa agcggtaata aatatttcat ttttgatttt ttgttaaaaa     3360

aaaaaaaaaa aaa                                                        3373


<210>  1910
<211>  3256
<212>  DNA
<213>  homo sapiens

<400>  1910
tttaaagaga gaggatcgta ttatagatac cgcgggggca aagctaaaaa aggggggagg       60

ggggaggaaa aaattcaaga agcagaaacc cctcgcggag ttttactgga agaaaaaaac      120

gggtctgaaa gattcctcct cttcatcatc atcaaccatc attcattcac taccttgaca      180

ttccgggctt tgattgacag ctggagtggc aaaaagccat gaaacacgac agttcggtta      240

catgtgggct gctgacgggc cgctcgtaac cttcagttcg ggggcttgac aatttttttc      300

ttctttttct tctttttctt ttctttcttt ttttttccaa ctgaggggaa gagaagagaa      360

agagggggaa aggaggaccg aagaggagga ggaggggagg ggggaggagg aggaggtgga      420

ggaggaggag gaagatcagg aggaggagga agaagaggaa aaaagagaaa aagaagaaat      480

atcacagaaa aaaaaattct tcgttgtcta gactgggctt tttttccccc ctaaaaaata      540

gcatattgga gaattgggag aagtctcttt ggtttggaaa aaaaaaaaag gaatcttcag      600

cctagatcac tttcttatcc ggactgggat attaaatata cgacacatcc aggagtttat      660

tggagcgcag actgatggcg caaaggtacg atgagctgcc ccattacggc gggatggacg      720

gagtaggggt tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg      780

ttcaccacct gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc      840

cgcaccccaa tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg      900

acaaggacgc gatctatggg cacccgttgt ttcctctgtt agctctggtc tttgagaagt      960

gcgagctggc gacctgcact ccccgggaac ctggagtggc tggcggagac gtctgctcct     1020

ccgactcctt caacgaggac atcgcggtct tcgccaagca ggttcgcgcc gaaaagccac     1080

ttttttcctc aaatccagag ctggacaatt tgatgataca agcaatacaa gtactaaggt     1140

ttcatctttt ggagttagaa aaggtccacg aactgtgcga taacttctgc caccgataca     1200

ttagctgttt gaaggggaaa atgcccatcg acctcgtcat tgatgaaaga gacggcagct     1260

ccaagtcaga tcatgaagaa ctttcaggct cctccacaaa tctcgctgac cataaccctt     1320

cttcttggcg agaccacgat gatgcaacct caacccactc agcaggcacc ccagggccct     1380

ccagtggggg ccatgcttcc cagagcggag acaacagcag tgagcaaggg gatggtttag     1440

acaacagtgt agcttcacct ggtacaggtg acgatgatga tccggataag gacaaaaaac     1500

gccagaagaa aagaggcatt ttccccaaag tagcaacaaa tatcatgaga gcatggctct     1560

tccagcatct cacacatccg tacccttccg aagagcagaa gaaacagtta gcgcaagaca     1620

caggacttac aattctccaa gtaaacaact ggtttattaa tgccagaaga agaatagtac     1680

agcccatgat tgaccagtca aatcgagcag tgagccaagg agcagcatat agtccagagg     1740

gtcagcccat ggggagcttt gtgttggatg gtcagcaaca catggggatc cggcctgcag     1800

gtttgcagag catgccaggg gactacgttt ctcagggtgg tcctatggga atgagtatgg     1860

cacagccaag ttacactcct ccccagatga ccccacaccc tactcaatta agacatggac     1920

ccccaatgca ttcatatttg ccaagccatc cccaccaccc agccatgatg atgcacggag     1980

gaccccctac ccaccctgga atgactatgt cagcacagag ccccacaatg ttaaattctg     2040

tagatcccaa tgttggcgga caggttatgg acattcatgc ccaatagtat aagggaactc     2100

aagggaaaag gaaacacacg caaaaactat tttaagactt tctgaacttt gaccagatgt     2160

tgacacttaa tatgaaattc cagacagctg tgattatttt ttacttttgt catttttcat     2220

caagcaacag aggaccaatg caacaagaac acaaatgtga aatcatgggc tgactgagac     2280

aattctgtcc atgtaaagat cctctggaaa aagactccga gagttataac tactgtagta     2340

taaatatagg aactaagtta aacttgtaca tttctgttga tcacgccgtt atgttgcctc     2400

aaatagtttt agaagagaaa aaaaaatata tccttgtttt ccacactatg tgtgttgttc     2460

ccaaaagaat gactgttttg gttcatcagt gaattcacca tccaggagag actgtggtat     2520

atattttaaa cctgttgggc caatgagaaa agaaccacac tggagatcat gatgaacttt     2580

tggctgaacc tcatcactcg aactccagct tcaagaatgt gttttcatgc ccggcctttg     2640

ttcctccata aatgtgtcct ttagtttcaa acagatcttt atagttcgtg cttcataagc     2700

caattcttat tattattttt gggggactct tcttcaaaga gcttgccaat gaagatttaa     2760

agacagagca ggagcttctt ccaggagttc tgagccttgg ttgtggacaa aacaatctta     2820

agttgggcag ctttcctcaa cacaaaaaaa agttattaat ggtcattgaa ccataactag     2880

gactttatca gaaactcaaa gcttggggga taaaaaggag caagagaata ctgtaacaaa     2940

cttcgtacag agttcggtct attaattgtt tcatgttaga tattctatgt gtttacctca     3000

attgaaaaaa aaaagaatgt ttttgctagt atcagatctg ctgtggaatt ggtattgtat     3060

gtccatgaat tcttcttttc tcagcacgtg ttcctcacta gaagaaaatg ctgttacctt     3120

taagctttgt caaatttaca ttaaaatact tgtatgagga ctgtgacgtt atgttaaaaa     3180

aaaaaaggtg ttaagtcaca aaaagcggta ataaatattt catttttgat tttttgttaa     3240

aaaaaaaaaa aaaaaa                                                     3256


<210>  1911
<211>  3646
<212>  DNA
<213>  homo sapiens

<400>  1911
ggcgccacca cgtgtgtccc tgcgcccggt ggccaccgac tcagtccctc gccgaccagt       60

ctgggcagcg gaggagggtg gttggcagtg gctggaagct tcgctatggg aagtcgttcc      120

tttgctctct cgcgcccagt cctcctccct ggttctcctc agccgctgtc ggaggagagc      180

acccggagac gcgggctgca gtcgcggcgg cttctccccg cctgggcggc cgcgccgctg      240

ggcaggtgct gagcgcccct agagcctccc ttgccgcctc cctcctctgc ccggccgcag      300

cagtgcacat ggggtgttgg aggtagatgg gctcccggcc cgggaggcgg cggtggatgc      360

ggcgctgggc agaagcagcc gccgattcca gctgccccgc gcgccccggg cgcccctgcg      420

agtccccggt tcagccatgg ggacctctcc gagcagcagc accgccctcg cctcctgcag      480

ccgcatcgcc cgccgagcca cagccacgat gatcgcgggc tcccttctcc tgcttggatt      540

ccttagcacc accacagctc agccagaaca gaaggcctcg aatctcattg gcacataccg      600

ccatgttgac cgtgccaccg gccaggtgct aacctgtgac aagtgtccag caggaaccta      660

tgtctctgag cattgtacca acacaagcct gcgcgtctgc agcagttgcc ctgtggggac      720

ctttaccagg catgagaatg gcatagagaa atgccatgac tgtagtcagc catgcccatg      780

gccaatgatt gagaaattac cttgtgctgc cttgactgac cgagaatgca cttgcccacc      840

tggcatgttc cagtctaacg ctacctgtgc cccccatacg gtgtgtcctg tgggttgggg      900

tgtgcggaag aaagggacag agactgagga tgtgcggtgt aagcagtgtg ctcggggtac      960

cttctcagat gtgccttcta gtgtgatgaa atgcaaagca tacacagact gtctgagtca     1020

gaacctggtg gtgatcaagc cggggaccaa ggagacagac aacgtctgtg gcacactccc     1080

gtccttctcc agctccacct caccttcccc tggcacagcc atctttccac gccctgagca     1140

catggaaacc catgaagtcc cttcctccac ttatgttccc aaaggcatga actcaacaga     1200

atccaactct tctgcctctg ttagaccaaa ggtactgagt agcatccagg aagggacagt     1260

ccctgacaac acaagctcag caagggggaa ggaagacgtg aacaagaccc tcccaaacct     1320

tcaggtagtc aaccaccagc aaggccccca ccacagacac atcctgaagc tgctgccgtc     1380

catggaggcc actgggggcg agaagtccag cacgcccatc aagggcccca agaggggaca     1440

tcctagacag aacctacaca agcattttga catcaatgag catttgccct ggatgattgt     1500

gcttttcctg ctgctggtgc ttgtggtgat tgtggtgtgc agtatccgga aaagctcgag     1560

gactctgaaa aaggggcccc ggcaggatcc cagtgccatt gtggaaaagg cagggctgaa     1620

gaaatccatg actccaaccc agaaccggga gaaatggatc tactactgca atggccatgg     1680

tatcgatatc ctgaagcttg tagcagccca agtgggaagc cagtggaaag atatctatca     1740

gtttctttgc aatgccagtg agagggaggt tgctgctttc tccaatgggt acacagccga     1800

ccacgagcgg gcctacgcag ctctgcagca ctggaccatc cggggccccg aggccagcct     1860

cgcccagcta attagcgccc tgcgccagca ccggagaaac gatgttgtgg agaagattcg     1920

tgggctgatg gaagacacca cccagctgga aactgacaaa ctagctctcc cgatgagccc     1980

cagcccgctt agcccgagcc ccatccccag ccccaacgcg aaacttgaga attccgctct     2040

cctgacggtg gagccttccc cacaggacaa gaacaagggc ttcttcgtgg atgagtcgga     2100

gccccttctc cgctgtgact ctacatccag cggctcctcc gcgctgagca ggaacggttc     2160

ctttattacc aaagaaaaga aggacacagt gttgcggcag gtacgcctgg acccctgtga     2220

cttgcagcct atctttgatg acatgctcca ctttctaaat cctgaggagc tgcgggtgat     2280

tgaagagatt ccccaggctg aggacaaact agaccggcta ttcgaaatta ttggagtcaa     2340

gagccaggaa gccagccaga ccctcctgga ctctgtttat agccatcttc ctgacctgct     2400

gtagaacata gggatactgc attctggaaa ttactcaatt tagtggcagg gtggtttttt     2460

aattttcttc tgtttctgat ttttgttgtt tggggtgtgt gtgtgtgttt gtgtgtgtgt     2520

gtgtgtgtgt gtgtgtgtgt gtgtttaaca gagaatatgg ccagtgcttg agttctttct     2580

ccttctctct ctctcttttt tttttaaata actcttctgg gaagttggtt tataagcctt     2640

tgccaggtgt aactgttgtg aaatacccac cactaaagtt ttttaagttc catattttct     2700

ccattttgcc ttcttatgta ttttcaagat tattctgtgc actttaaatt tacttaactt     2760

accataaatg cagtgtgact tttcccacac actggattgt gaggctctta acttcttaaa     2820

agtataatgg catcttgtga atcctataag cagtctttat gtctcttaac attcacacct     2880

actttttaaa aacaaatatt attactattt ttattattgt ttgtccttta taaattttct     2940

taaagattaa gaaaatttaa gaccccattg agttactgta atgcaattca actttgagtt     3000

atcttttaaa tatgtcttgt atagttcata ttcatggctg aaacttgacc acactattgc     3060

tgattgtatg gttttcacct ggacaccgtg tagaatgctt gattacttgt actcttctta     3120

tgctaatatg ctctgggctg gagaaatgaa atcctcaagc catcaggatt tgctatttaa     3180

gtggcttgac aactgggcca ccaaagaact tgaacttcac cttttaggat ttgagctgtt     3240

ctggaacaca ttgctgcact ttggaaagtc aaaatcaagt gccagtggcg ccctttccat     3300

agagaatttg cccagctttg ctttaaaaga tgtcttgttt tttatataca cataatcaat     3360

aggtccaatc tgctctcaag gccttggtcc tggtgggatt ccttcaccaa ttactttaat     3420

taaaaatggc tgcaactgta agaacccttg tctgatatat ttgcaactat gctcccattt     3480

acaaatgtac cttctaatgc tcagttgcca ggttccaatg caaaggtggc gtggactccc     3540

tttgtgtggg tggggtttgt gggtagtggt gaaggaccga tatcagaaaa atgccttcaa     3600

gtgtactaat ttattaataa acattaggtg tttgttactt aaaaaa                    3646


<210>  1912
<211>  7441
<212>  DNA
<213>  homo sapiens

<400>  1912
agaggagccg ggacaccgag ggaagaggcc ggagggagat cgcggagggg agggggcggg       60

aggggggtgg ggtatcctga gtcgtccgtg gtccggagtc tggaaggccc tagagcggcg      120

ccagtcgacc cgcctcgcca caacttgccc agaccagaca cgtttcatcc tgcgccctgc      180

aagaaggagc cggcctgcct ctctccgctt tgctgctcct cggcctccgc gggcccggcc      240

cgcgtcagca gcgaccctgg ggtctgggtc ccctgtgtcg cccccgcccg cctgcagcgc      300

ccggcacccg cccaggagcg cgcagctggg gttctaggga cgtatacttg agcaagagag      360

accacagctc ttgttcccgc tgatcctgca gcccagtgga tggagtccag aatctacaga      420

cctgccagga aagaaaaaaa aattcctgat gtctggtcca agcaggaatt ccccggtgga      480

ttggggaatg tctggctttt cctcagctta ttgatctctg tggtaaccac tggaggcccc      540

cagaagaccc atagaaatga gaggcctgag gtctacaagt cgctgctaga aatattttag      600

cctctccaaa gcccagaatg cagccccgac ccaagtttgt aagggttctg ggtgcacgct      660

gaccctgcgc gggcagacgc gccctttgct ccaggtccgg acctgggcgc tgctatagca      720

acgtcctgga cgcccagacc ttaggccgcc gccgccgcgg aagcgaggaa cccggccttc      780

tcccgctcct gagggctgtg gcggcggcgg cccgggaggc ggcccaggct gggtaaagac      840

cgcccggctc ctcctatgca agctgaggca gcggattggt tttcaagcat gcccttccag      900

aagcatgtct actacccgct cgccagcggc ccagaggggc ccgacgtcgc tgtggccgcc      960

gccgccgcgg gtgcggcctc catggcctgt gcgcccccca gcgcggcttc ggggcccctg     1020

cccttcttcc agttcaggcc gcggctggag agtgtggact ggcggcggct gagcgccatc     1080

gacgtggaca aggtggcggg ggctgtggac gtgctgacgc tgcaggagaa catcatgaac     1140

atcaccttct gcaagctgga agacgagaag tgcccacact gccagtcggg ggtggacccg     1200

gtgctgctga agctcatccg tctggcgcag ttcaccatcg agtacttgct gcactcacaa     1260

gagttcctca cctcgcagct gcacaccctg gaggagcggc tgcgcctgag ccactgcgac     1320

ggcgagcaga gcaagaagct gctcaccaag caggcggggg agatcaagac gctcaaggaa     1380

gagtgcaaac gccggaagaa gatgatctcc acccagcagc tgatgatcga ggccaaagcc     1440

aactattacc agtgccattt ttgtgacaag gcctttatga accaagcttt tctacaaagt     1500

cacattcaac gccgccacac tgaagaaaat tctcattttg agtatcagaa aaatgcacag     1560

attgagaagc tccggagtga gatcgtcgta ttgaaggaag agctgcagct caccaggtct     1620

gagctagagg ctgcacacca tgccagtgca gtcagattct ccaaggaata tgaaatgcag     1680

aaaacaaaag aggaagactt tttgaagtta tttgacaggt ggaaagaaga agaaaaggag     1740

aaactagttg atgaaatgga aaaagtcaag gagatgttta tgaaggaatt taaagaatta     1800

acttcgaaga attcagcatt agaatatcaa ctgtcagaaa tccagaagtc caatatgcag     1860

atcaagtcca acataggcac attaaaagat gcacacgagt ttaaagaaga ccgttctcca     1920

tatccccagg atttccataa tgtcatgcag cttcttgata gtcaggaaag caaatggaca     1980

gctcgagttc aagctattca tcaagaacac aagaaagaga agggtcggct cctgtcacat     2040

atagagaaac ttcgaacctc aatgatagat gatctaaatg caagcaatgt tttctataag     2100

aaaaggatag aagagctagg gcagagactc caggagcaga atgagctgat tataactcag     2160

agacagcaga ttaaagactt tacctgtaat ccattaaaca gtatcagtga acccaaagtg     2220

aatgccccag ccctgcacac tttggaaact aaatcaagtc tgccaatggt gcatgaacag     2280

gcattctcgt cgcacatact ggaaccaata gaagaacttt cagaggaaga aaaaggaagg     2340

gaaaatgaac agaaattaaa taacaacaaa atgcatttaa ggaaagcttt gaagagtaac     2400

tcctccctca ctaagggact aagaacaatg gtggagcaga acttgatgga gaaactggaa     2460

accttgggga ttaatgcaga tatacgtggc atttcaagtg atcagttgca tagagtacta     2520

aaaagtgtgg aatcagaaag acataagcaa gaaagagaaa tacctaactt tcatcaaatt     2580

cgagaattcc ttgaacatca agtcagctgt aaaattgagg agaaagcact actctcttca     2640

gatcagtgca gtgtttctca aatggatacc ctttcaactg gagaagtacc caaaatgata     2700

caacttcctt ccaaaaacag acaactgatt agacaaaaag ctgtttctac tgataggaca     2760

tctgttccaa aaattaagaa aaatgtcatg gaagatcctt ttcccagaaa gtcttcaact     2820

attacgaccc ctccttttag ttcagaggag gagcaggagg acgacgacct catccgggca     2880

tacgcatccc caggcccact tcctgtgccg ccaccacaaa acaagggcag cttcgggaag     2940

aacacagtga aaagtgacgc ggacgggacc gagggaagcg aaatcgagga cactgatgat     3000

tctcccaagc ccgcaggagt cgccgttaaa acacctactg aaaaagttga aaagatgttt     3060

ccacatcgca aaaatgtgaa caaaccagtc ggtggaacta atgtccctga gatgtttatc     3120

aaaaaagaag aattacaaga actaaagtgt gcggatgtgg aggatgaaga ctgggacata     3180

tcatccctag aggaagagat atctttggga aaaaaatctg ggaaagaaca gaaggaacct     3240

ccacctgcga aaaatgaacc acattttgct catgtgctaa atgcctgggg cgcatttaat     3300

cctaaggggc caaagggaga aggacttcaa gaaaatgaat caagcacatt aaaaagcagc     3360

ttagtaactg tgactgattg gagcgacact tcagatgtct aattccacat gtcagaagat     3420

tattccagaa gccagcagta tttcagtatc acagtgtttc agtaatttgc ctccatgatt     3480

ctagtgcttc tgccttaccg tgtttcccac agcaacacag agactgattc aaagaacaat     3540

ggtctcttta atggcaccca atacagtatt gaaaatcaga tcatcaacag tatttcgaag     3600

catgtaaagg tgtttaagac ttccgctgct gcttaaaaat aacatgtcat tgaagtcata     3660

aaaagttttt tcttcagaaa ggtactctag tgttaagtgt atttttttca actaattttt     3720

tagtgaattt tttttaaact tacagcatgt tttggtttga attactaaaa ctttaaaaaa     3780

tatttttctt atgtatgctg tcgtatcgta ggcgtttata ttataaaatt ctgttagtag     3840

tcttaaaatt gaattggtgg aaccactaat ccttaaaagt tagtctggtt atttttcata     3900

tagaagtaag tttaatccga gtgtggtggt gttcaccttt aatcccagct acttgggagg     3960

ctgaggtggg aggataactt gagcacagga gttcaagacc agcgtgggca atatagcaag     4020

actccacccc tccacacccc aaaaaagtaa gtttaggatt agaatatagc taggtccaat     4080

gttaaataca ttttcctgga gtacatttgt cacattcagc tttgagccac tgtaagcatg     4140

ttactattaa atggttggtt attttatata gcatattctt tatcttggat attttatgaa     4200

taaagtatag ttattttaag tgccaattaa tttatcagac taaatagaaa atatttgagc     4260

cattactgaa ttcacatatg tatgtttttt tttactattt aaaataccca acatgtatta     4320

tgaaatacct caaaagtaat ttagttacat tcttaaacaa tgacattgtc gaaagaaagt     4380

tcttataagc tgttttttgc atttttataa cttggttata ctatattctg tttccaagta     4440

accttttaac taaaagattt gttgggtttt agatctcttt tcatttgtca accttttcag     4500

taaagccctc tgttacatca ctgtgactgt ggctgtgtta ttagagatga attctgagtt     4560

aaatttgtac ttattagggg tcttacagag ggagaatctg gccttgattg ctatgccata     4620

tgacattctg tcctaatggt tagaacaaat ctttatctgt ttccacccac cctgggatcc     4680

tttttacttg tagcccattc ctgccctcta aaagaatcct tccaacttcc tataggggcc     4740

atttcatgca gatatactca ctttatatgt atgtttctaa aagctttagt gaaggctgaa     4800

tccaagtttc atgtagtagg acagagaaca gaaggccgaa tccaagtttc atgtggtagg     4860

acagagaacg gcaatctaca aaactacacc aagcctaaga tggcccatgt gccactttgt     4920

tcattcattt atttattcag cagatattta ttgaaccact tggtctggtt tggttttgaa     4980

cacgcactaa ttcatttaat tacaacaact ttgcgatgta gttattgtta taatcctcat     5040

cctaaaggtg tgagaaacag agttattaag taagttgcca gaagccatac aagtacaaag     5100

tgtcaagggg agactttaag ccaggtctct attccatgtt ttgtgtctgc catgttttca     5160

ttcctgagca gaagagcttg gggaaatgaa cttttgctaa gtaaacccag tatttaaatt     5220

aagtcactat atctgtgtct tttaagagcc cctcctttag cttacatggt tagttgtatc     5280

tttttttttt tttttttttg agacagagtc tcactatgtt gcccaggctt gagcgcagtg     5340

gcaccatctc ggctcactac aacctccgcc tcccagattc aagcgatttt cctgcctcag     5400

cctcccaagt agctgggatt acaggtgccc accaccatgc ctggcttaat tttttgtatt     5460

tttagtagag atgaggtttc accatgttgg ccagactggt ctcgaactcc tgacctcaaa     5520

tgatccgctg tcttgtcctc ccaaagtgct gggattatag gcgtgagcca tcgcgccctg     5580

ctgcatttca tttttttgta taaaatttgg tttgttcgtt tttgagggga accattcctt     5640

tatgttgccc cttactgatg cccaactaat gtgtttctgg ttactaacag accttcatcc     5700

cccaccctcc ctaaattctt cggtgtaatc taagcgttat ctgcaccact tctgaataat     5760

aaatgtgttt gaaatgcaca cctacacaac cctgtcccac actggcctgt aggacctaat     5820

ctaccttcat gtctttcagt tgatttgtat ttctgcaaaa gatatttcaa ggattatcaa     5880

ggtatggaat tttttttatt ttttatcttt taacaaactt gttcatttcc ttttctttcc     5940

attgagcacc tctgaacaat gtgattcttt tttttaagtc tttcacactt caggaaaata     6000

ctacattcac ccacgttgtg attcatatcg gacagtttct tactcaaaga taacacaaat     6060

accaattctt attcatactt tgaaactata ttttacccta gactgccttg gttcaaaggc     6120

ctagtttcga cattactgtg gcaaattatt taagctctct gttttcattt ctttttctgt     6180

aaatgcagga tgaaaacaat atgtatctcc taggatggct gtgaggagtg agtgagacag     6240

gacatgaaag gtgtgtatga actgtgataa ctgttgccct tgtgggcatg ttatataggg     6300

ctggctctag gaagaagcct gtgtcttttt tcagaaatcc ctggagcaac ttaaatgtct     6360

ttagaaatga caagtctctc agttatccag ttagccgtaa acaggttctg gaagacacac     6420

ctagatagaa ctcggcccgt cagttctgag tgaggcacgt accacttggg cttgggatgt     6480

ccttaaccca tttatgcctg aggttgcaat tttttgaatt tttccaatca caccttggcg     6540

atgaccttga gcagtaggat ataaataact cccacatgct tagtgttcca ataatggaac     6600

actaggcata aacaggtttt aattggctcc tcagtcaacc atgaccaata tctctatctc     6660

agcttctgct gatgccctag ctcagggctc tgcattccgt gccagggacg cctcagcccc     6720

ttaacatgga tgtgccacat gacaggcaat aatatattgg ccccattagc ccttcctgga     6780

gcagtcataa tgaattacag tcatgacagg cacatgtaag aaaccaaaat ttgctaaata     6840

tgtacatgag tcttcatcac agcatcgttt atgaaaacaa ctaaatattc actaatggtg     6900

ccagtggaat aaatcagaga acatcccctg ctacgtaact ctctgcatac atcaaagaga     6960

atggtgtggc tttgcttttt caacaatcta ctgagtggcc atgggcatgt ggatatggcc     7020

atgaatgagc aagatcctct ctgatcctgt agaagttaag ttctaccaga taacttgctg     7080

cttcaacaaa aagatttacc tttttaaata aatgttgtag aatacttaaa aaaaacaaac     7140

tagaatttgc ctgtgtgcag ccagtaacat gtctatttaa cctggacacc ttttgaggaa     7200

tattctcaga ttgcccccat gctgtttata agacattgtt ccttatacac ctgtttatga     7260

atgaaaagaa acataaggag tgggtacaaa gacttctatc tatgaatgat taaaaaggct     7320

agagtacgaa tacttcttga acctttggta ctaaatgctt ttcatgttct atataaatgt     7380

agaaaacatt ttacaaatcc tgtaaataaa ctgtttattt tttatagaaa gccaaaaaaa     7440

a                                                                     7441


<210>  1913
<211>  1131
<212>  DNA
<213>  homo sapiens

<400>  1913
tggagagagc ggctctcgtg gctggggagt tggatgcacc aaacctgtgt gcggctggag       60

agggaggctt ctgccagacc ctctcccggg cctgtcctgc cacccaggcc cctccccagt      120

ctcacactga gctccagatc agggaagggc cgaaaaggac gatcagggca gccgcagaag      180

gggcgccctg cgtgggacgg gtccgttgcg cgcctggtaa ccgaggggga agggaagggg      240

cctctggcgt gcggggcggt gtcgcgcagg tcccaccccg cctgcccgcg ccgcccattg      300

gtcccgagcg cgatgacttg gcgggcggag caggaaggaa accgctcccg agcacggcgg      360

cggcgtcgtc tcccggcagt gcagctgccg ctaccgccgc cctctgcccg ccggcccgtc      420

tgtctacccc cagcatgagc ggcctgcgcg tctacagcac gtcggtcacc ggctcccgcg      480

aaatcaagtc ccagcagagc gaggtgaccc gaatcctgga tgggaagcgc atccaatacc      540

agctagtgga catctcccag gacaacgccc tgagggatga gatgcgagcc ttggcaggca      600

accccaaggc caccccaccc cagattgtca acggggacca gtactgtggg gactatgagc      660

tcttcgtgga ggctgtggaa caaaacacgc tgcaggagtt cctgaagctg gcttgagtca      720

agcctgtcca gagttcccct gctggactcc atcaccacac tccccccagc cttcacctgg      780

ccatgaagga ccttttgacc aactccctgt cattcctaac ctaaccttag agtccctccc      840

ccaatgcagg ccacttctcc tccctcctct ctaaatgtag tcccctctcc tccatctaaa      900

ggcaacattc cttacccatt agtctcagaa attgtcttaa gcaacagccc caaatgctgg      960

ctgcccccag ccaagcattg gggccgccat cctgcctggc actggctgat gggcacctct     1020

gttggttcca tcagccagag ctctgccaaa ggccccgcag tccctctccc aggaggaccc     1080

tagaggcaat taaatgatgt cctgttccat tggcaaaaaa aaaaaaaaaa a              1131


<210>  1914
<211>  3033
<212>  DNA
<213>  homo sapiens

<400>  1914
ctcggtggcg gcggcggcgg ccggctccag gccgggtttt ggcgccgccc gcctgctgcc       60

tcctggcggc tcctgaactc cagccccctc tctatcagcc gctcactccg tctcaatatg      120

tctcaagatg gcggccaatg tgggatcgat gtttcaatat tggaagcgct ttgatttaca      180

gcagctgcag agagaactcg atgccaccgc aacggtattg gcgaaccggc aggatgaaag      240

tgagcagtcc agaaagcggc ttatcgaaca gagccgggag ttcaagaaga acactccaga      300

ggatttgcgc aagcaggtag cgccgctgct gaagagtttc caaggagaga ttgatgcact      360

gagtaaaaga agcaaggaag ctgaagcagc tttcttgaat gtctacaaaa gattgattga      420

cgtcccagat cccgtaccag ctttggatct cggacagcaa ctccagctca aagtgcagcg      480

cctgcacgat attgaaacag agaaccagaa acttagggaa actctggaag aatacaacaa      540

ggaatttgct gaagtgaaaa atcaagaggt tacgataaaa gcacttaaag agaaaatccg      600

agaatatgaa cagacactga agaaccaagc cgaaaccata gctcttgaga aggaacagaa      660

gttacagaat gactttgcag aaaaggagag aaagctgcag gagacacaga tgtccaccac      720

ctcaaagctg gaggaagctg agcataaggt tcagagccta caaacagccc tggaaaaaac      780

tcgaacagaa ttatttgacc tgaaaaccaa atacgatgaa gaaactactg caaaggccga      840

cgagattgaa atgatcatga cggaccttga aagggcaaac cagagggcag aggtggctca      900

gagagaggcg gagaccttaa gggaacagct ctcatcggcc aatcactccc tccagctggc      960

ctcacagatc cagaaggcac cagacgtggc catagaggtg ctgacccgct ccagcctaga     1020

agttgagttg gccgccaagg agcgggagat cgcacagctg gtggaggacg tgcagagact     1080

ccaggccagc ctcaccaagc tgcgggagaa ttcggccagc cagatctcac agcttgagca     1140

gcagctgagc gccaaaaaca gcacactcaa acaactggaa gaaaaactca aaggccaggc     1200

tgactatgaa gaggtgaaga aagagctgaa cattctgaag tccatggagt ttgcaccgtc     1260

cgagggcgct gggacacagg atgcggccaa gcccctggag gtgctgttgc tggagaagaa     1320

ccgctcgctg cagtccgaga acgccgcgct gcgcatctcc aacagcgacc tgagcggacg     1380

ctgtgcggag ctgcaagtcc gtatcactga ggctgtggcc acagccactg agcagagaga     1440

gctgatcgcc cgcctggagc aggacctgag catcattcag tccatccagc ggcccgatgc     1500

cgagggtgcc gctgagcacc gcctggagaa gatcccagag cccatcaaag aggccactgc     1560

cctattctac ggacctgcag caccagccag cggtgccctc ccagagggcc aggtggattc     1620

actgctttcc atcatctcca gccagaggga gcgcttccgt gcccggaacc aggagcttga     1680

ggccgagaac cgcctggccc agcacaccct ccaggccctg cagagtgagc tggacagcct     1740

gcgcgccgac aacatcaagc tctttgagaa gatcaagttc ctgcagagct accctggccg     1800

gggcagcggc agtgatgaca cggagctgcg gtactcgtcc cagtacgagg agcgcctgga     1860

ccccttctcc tccttcagca agcgggagcg gcagaggaag tacctgagct tgagtccctg     1920

ggacaaggcc accctcagca tggggcgtct ggttctctcc aacaagatgg cgcgcaccat     1980

cggcttcttc tacacactgt tcctgcactg cctggtcttc ctggtgctct acaagctggc     2040

atggagcgag agcatggaga gggactgtgc caccttctgc gccaagaagt tcgctgacca     2100

cctgcacaag ttccacgaga atgacaacgg ggctgcggct ggtgacttgt ggcagtgata     2160

ccccggggcc tcccccgtga cagtgacggc tgcgcctcca ccccgactgc tcagtgcatc     2220

taatcactta gactcccctg aagaatcccc catggaaact gcccttatcc gctgtccagc     2280

agctgccaga ggccccaggt cacctcgggt ccccttgaaa gaatgtctcg gtcacatcag     2340

gcccgctagg tccagagagc gagcccccaa tgcccggcca ggctaagccg cagagaccct     2400

ctcagccccc acctcaggtt agggctctgc ccgcagcctg acctctagcc ctggtggcag     2460

aggtccctca gctgcgaggc taattgggtg accaccgatt ccagctgcgg ttaatccagc     2520

ttgggcctgt ctgcactgcg atcctcttgg gctctcctag gatcccccca tgccccgtaa     2580

gaggtggaag acgcttcctt ccaggacagc aggctttgag tccagcaccc ccagcctgcc     2640

tttgccacca gccccaccct gcagagtata tgaggcttga cagagtctgc cccctccccc     2700

actgcacccc aagagagaga gccccagcca gcggaacagt ttctattacc ccctccctgc     2760

ccccagaccc atgtgatttc tgctttcttc tttagcaaga tattctggtt tctagataag     2820

gaagagtctc taatgagccc ccgagcccca gtctcttcag actcatggat tggtatgagg     2880

ggtctgaacg tctcctagcc aatcagaact ggctgtggac caccctagca cggccacctc     2940

tcagggccac tggcaggcct tcctgagtta gatttgtagt tgcatattta gctttgcaca     3000

tttgaaataa accacggttg cagccaaaaa aaa                                  3033


<210>  1915
<211>  2114
<212>  DNA
<213>  homo sapiens

<400>  1915
gagagatgtg ggttacaaag ctgccatcta gaggctagag gctcctttct gcagtgtata       60

taatgcaagt ctgcagccag cagagctcac agttgttgca aagtgctcag cactaaggga      120

gccagcgcac agcacagcca ggaaggcgag cgagcccagc cagcccagcc agcccagcca      180

gcccggaggt catttgattg cccgcctcag aacgatggat ctgcatctct tcgactactc      240

agagccaggg aacttctcgg acatcagctg gccatgcaac agcagcgact gcatcgtggt      300

ggacacggtg atgtgtccca acatgcccaa caaaagcgtc ctgctctaca cgctctcctt      360

catttacatt ttcatcttcg tcatcggcat gattgccaac tccgtggtgg tctgggtgaa      420

tatccaggcc aagaccacag gctatgacac gcactgctac atcttgaacc tggccattgc      480

cgacctgtgg gttgtcctca ccatcccagt ctgggtggtc agtctcgtgc agcacaacca      540

gtggcccatg ggcgagctca cgtgcaaagt cacacacctc atcttctcca tcaacctctt      600

cggcagcatt ttcttcctca cgtgcatgag cgtggaccgc tacctctcca tcacctactt      660

caccaacacc cccagcagca ggaagaagat ggtacgccgt gtcgtctgca tcctggtgtg      720

gctgctggcc ttctgcgtgt ctctgcctga cacctactac ctgaagaccg tcacgtctgc      780

gtccaacaat gagacctact gccggtcctt ctaccccgag cacagcatca aggagtggct      840

gatcggcatg gagctggtct ccgttgtctt gggctttgcc gttcccttct ccattatcgc      900

tgtcttctac ttcctgctgg ccagagccat ctcggcgtcc agtgaccagg agaagcacag      960

cagccggaag atcatcttct cctacgtggt ggtcttcctt gtctgctggc tgccctacca     1020

cgtggcggtg ctgctggaca tcttctccat cctgcactac atccctttca cctgccggct     1080

ggagcacgcc ctcttcacgg ccctgcatgt cacacagtgc ctgtcgctgg tgcactgctg     1140

cgtcaaccct gtcctctaca gcttcatcaa tcgcaactac aggtacgagc tgatgaaggc     1200

cttcatcttc aagtactcgg ccaaaacagg gctcaccaag ctcatcgatg cctccagagt     1260

ctcagagacg gagtactctg ccttggagca gagcaccaaa tgatctgccc tggagaggct     1320

ctgggacggg tttacttgtt tttgaacagg gtgatgggcc ctatggtttt ctagagcaaa     1380

gcaaagtagc ttcgggtctt gatgcttgag tagagtgaag aggggagcac gtgccccctg     1440

catccattct ctctttctct tgatgacgca gctgtcattt ggctgtgcgt gctgacagtt     1500

ttgcaacagg cagagctgtg tcgcacagca gtgctgtgcg tcagagccag ctgaggacag     1560

gcttgcctgg acttctgtaa gataggattt tctgtgtttc ctgaattttt tatatggtga     1620

tttgtattta aattttaaga ctttattttc tcactattgg tgtaccttat aaatgtattt     1680

gaaagttaaa tatattttaa atattgtttg ggaggcatag tgctgacata tattcagagt     1740

gttgtagttt taaggttagc gtgacttcag ttttgactaa ggatgacact aattgttagc     1800

tgttttgaaa ttatatatat ataaatatat ataaatatat aaatatatgc cagtcttggc     1860

tgaaatgttt tatttaccat agttttatat ctgtgtggtg ttttgtaccg gcacgggata     1920

tggaacgaaa actgctttgt aatgcagttt gtgacattaa tagtattgta aagttacatt     1980

ttaaaataaa caaaaaactg ttctggactg caaatctgca cacacaacga acagttgcat     2040

ttcagagagt tctctcaatt tgtaagttat ttttttttaa taaagatttt tgtttcctaa     2100

aaaaaaaaaa aaaa                                                       2114


<210>  1916
<211>  2471
<212>  DNA
<213>  homo sapiens

<400>  1916
agtccctgcc ctcccctggg gagggtgagt cacgccaaac tgggcggaga gtccgctggc       60

ctcactccta gctcatctgg gcggcggcgg caagtgggga cagggcgggt ggcgcatcac      120

cggcgcggag gcaggaggag cagtctcatt gttccgggag ccgtcaccac agtaggtccc      180

tcggctcagt cggcccagcc cctctcagtc ctccccaacc cccacaaccg cccgcggctc      240

tgagacgcgg ccccggcggc ggcggcagca gctgcagcat catctccacc ctccagccat      300

ggaagacctg gaccagtctc ctctggtctc gtcctcggac agcccacccc ggccgcagcc      360

cgcgttcaag taccagttcg tgagggagcc cgaggacgag gaggaagaag aggaggagga      420

agaggaggac gaggacgaag acctggagga gctggaggtg ctggagagga agcccgccgc      480

cgggctgtcc gcggccccag tgcccaccgc ccctgccgcc ggcgcgcccc tgatggactt      540

cggaaatgac ttcgtgccgc cggcgccccg gggacccctg ccggccgctc cccccgtcgc      600

cccggagcgg cagccgtctt gggacccgag cccggtgtcg tcgaccgtgc ccgcgccatc      660

cccgctgtct gctgccgcag tctcgccctc caagctccct gaggacgacg agcctccggc      720

ccggcctccc cctcctcccc cggccagcgt gagcccccag gcagagcccg tgtggacccc      780

gccagccccg gctcccgccg cgcccccctc caccccggcc gcgcccaagc gcaggggctc      840

ctcgggctca gtggatgaga ccctttttgc tcttcctgct gcatctgagc ctgtgatacg      900

ctcctctgca gttgttgacc tcctgtactg gagagacatt aagaagactg gagtggtgtt      960

tggtgccagc ctattcctgc tgctttcatt gacagtattc agcattgtga gcgtaacagc     1020

ctacattgcc ttggccctgc tctctgtgac catcagcttt aggatataca agggtgtgat     1080

ccaagctatc cagaaatcag atgaaggcca cccattcagg gcatatctgg aatctgaagt     1140

tgctatatct gaggagttgg ttcagaagta cagtaattct gctcttggtc atgtgaactg     1200

cacgataaag gaactcaggc gcctcttctt agttgatgat ttagttgatt ctctgaagtt     1260

tgcagtgttg atgtgggtat ttacctatgt tggtgccttg tttaatggtc tgacactact     1320

gattttggct ctcatttcac tcttcagtgt tcctgttatt tatgaacggc atcaggcaca     1380

gatagatcat tatctaggac ttgcaaataa gaatgttaaa gatgctatgg ctaaaatcca     1440

agcaaaaatc cctggattga agcgcaaagc tgaatgaaaa cgcccaaaat aattagtagg     1500

agttcatctt taaaggggat attcatttga ttatacgggg gagggtcagg gaagaacgaa     1560

ccttgacgtt gcagtgcagt ttcacagatc gttgttagat ctttattttt agccatgcac     1620

tgttgtgagg aaaaattacc tgtcttgact gccatgtgtt catcatctta agtattgtaa     1680

gctgctatgt atggatttaa accgtaatca tatctttttc ctatctatct gaggcactgg     1740

tggaataaaa aacctgtata ttttactttg ttgcagatag tcttgccgca tcttggcaag     1800

ttgcagagat ggtggagcta gaaaaaaaaa aaaaaaagcc cttttcagtt tgtgcactgt     1860

gtatggtccg tgtagattga tgcagatttt ctgaaatgaa atgtttgttt agacgagatc     1920

ataccggtaa agcaggaatg acaaagcttg cttttctggt atgttctagg tgtattgtga     1980

cttttactgt tatattaatt gccaatataa gtaaatatag attatatatg tatagtgttt     2040

cacaaagctt agacctttac cttccagcca ccccacagtg cttgatattt cagagtcagt     2100

cattggttat acatgtgtag ttccaaagca cataagctag aagaagaaat atttctagga     2160

gcactaccat ctgttttcaa catgaaatgc cacacacata gaactccaac atcaatttca     2220

ttgcacagac tgactgtagt taattttgtc acagaatcta tggactgaat ctaatgcttc     2280

caaaaatgtt gtttgtttgc aaatatcaaa cattgttatg caagaaatta ttaattacaa     2340

aatgaagatt tataccattg tggtttaagc tgtactgaac taaatctgtg gaatgcattg     2400

tgaactgtaa aagcaaagta tcaataaagc ttatagactt aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa a                                                          2471


<210>  1917
<211>  1820
<212>  DNA
<213>  homo sapiens

<400>  1917
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag cagatcttct      120

ggtgacccca cttctcgctg ctcatgccgc tgggactggg gcggcggaaa aaggcgcccc      180

ctctagtgga aaatgaggag gctgagccag gccgtggagg gctgggcgtg ggggagccag      240

ggcctctggg cggaggtggg tcggggggcc cccaaatggg cttgcccccc cctcccccag      300

ccctgcggcc ccgcctcgtg ttccacaccc agctggccca tggcagtccc actggccgca      360

tcgagggctt caccaacgtc aaggagctgt atggcaagat cgccgaggcc ttccgcctgc      420

caactgccga ggtgatgttc tgcaccctga acacccacaa agtggacatg gacaagctcc      480

tggggggcca gatcgggctg gaggacttca tcttcgccca cgtgaagggg cagcgcaagg      540

aggtggaggt gttcaagtcg gaggatgcac tcgggctcac catcacggac aacggggctg      600

gctacgcctt catcaagcgc atcaaggagg gcagcgtgat cgaccacatc cacctcatca      660

gcgtgggcga catgatcgag gccattaacg ggcagagcct gctgggctgc cggcactacg      720

aggtggcccg gctgctcaag gagctgcccc gaggccgtac cttcacgctg aagctcacgg      780

agcctcgcaa ggccttcgac atgatcagcc agcgttcagc gggtggccgc cctggctctg      840

gcccacaact gggcactggc cgagggaccc tgcggctccg atcccggggc cccgccacgg      900

tggaggatct gccctctgcc tttgaagaga aggccattga gaaggtggat gacctgctgg      960

agagttacat gggtatcagg gacacggagc tggcggccac catggtggag ctgggaaagg     1020

acaaaaggaa cccggatgag ctggccgagg ccctggacga acggctgggt gactttgcct     1080

tccctgacga gttcgtcttt gacgtctggg gcgccattgg ggacgccaag gtcggccgct     1140

actaggactg cccccggacc ctgcgatgat gacccgggcg caacctggtg ggggccccca     1200

gcagggacac tgacgtcagg acccgagcct ccagcctgag cctagctcag cagcccaagg     1260

acgatggtga ggggaggtgg ggccaggccc cctgccccgc tccaatcggt accatcccct     1320

ccctggttcc cagtctggcc ggggtccccg gcccccctgt gccctgttcc ccacctacct     1380

cagctgggtc aggcacaggg aggggaggga tcagccaaat tgggcggcca cccccgcctc     1440

caccactttc caccatcagc tgccaaactg gtccctctgt ctccctgggg ccttgggttc     1500

tgtttggggg tcatgacctt cctagtttcc tgacgcaggg aatacagggg agagggttgt     1560

ccttcccccc agcaaatgca ataatgccct cacccctcct gagaggagcc ccctccctgt     1620

ggagcctgtt acctccgcat ttgacacgag tctgctgtga accccgcaac ctcctcccca     1680

cctcccatct ctccttccag gcccatccct ggcccagagc aggagggagg gagggacgat     1740

ggcggtgggt ttttgtatct gaatttgctg tcttgaacat aaagaatcta tctgctgttg     1800

gaaaaaaaaa aaaaaaaaaa                                                 1820


<210>  1918
<211>  1502
<212>  DNA
<213>  homo sapiens

<400>  1918
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag caggtgatgt      120

tctgcaccct gaacacccac aaagtggaca tggacaagct cctggggggc cagatcgggc      180

tggaggactt catcttcgcc cacgtgaagg ggcagcgcaa ggaggtggag gtgttcaagt      240

cggaggatgc actcgggctc accatcacgg acaacggggc tggctacgcc ttcatcaagc      300

gcatcaagga gggcagcgtg atcgaccaca tccacctcat cagcgtgggc gacatgatcg      360

aggccattaa cgggcagagc ctgctgggct gccggcacta cgaggtggcc cggctgctca      420

aggagctgcc ccgaggccgt accttcacgc tgaagctcac ggagcctcgc aaggccttcg      480

acatgatcag ccagcgttca gcgggtggcc gccctggctc tggcccacaa ctgggcactg      540

gccgagggac cctgcggctc cgatcccggg gccccgccac ggtggaggat ctgccctctg      600

cctttgaaga gaaggccatt gagaaggtgg atgacctgct ggagagttac atgggtatca      660

gggacacgga gctggcggcc accatggtgg agctgggaaa ggacaaaagg aacccggatg      720

agctggccga ggccctggac gaacggctgg gtgactttgc cttccctgac gagttcgtct      780

ttgacgtctg gggcgccatt ggggacgcca aggtcggccg ctactaggac tgcccccgga      840

ccctgcgatg atgacccggg cgcaacctgg tgggggcccc cagcagggac actgacgtca      900

ggacccgagc ctccagcctg agcctagctc agcagcccaa ggacgatggt gaggggaggt      960

ggggccaggc cccctgcccc gctccaatcg gtaccatccc ctccctggtt cccagtctgg     1020

ccggggtccc cggcccccct gtgccctgtt ccccacctac ctcagctggg tcaggcacag     1080

ggaggggagg gatcagccaa attgggcggc cacccccgcc tccaccactt tccaccatca     1140

gctgccaaac tggtccctct gtctccctgg ggccttgggt tctgtttggg ggtcatgacc     1200

ttcctagttt cctgacgcag ggaatacagg ggagagggtt gtccttcccc ccagcaaatg     1260

caataatgcc ctcacccctc ctgagaggag ccccctccct gtggagcctg ttacctccgc     1320

atttgacacg agtctgctgt gaaccccgca acctcctccc cacctcccat ctctccttcc     1380

aggcccatcc ctggcccaga gcaggaggga gggagggacg atggcggtgg gtttttgtat     1440

ctgaatttgc tgtcttgaac ataaagaatc tatctgctgt tggaaaaaaa aaaaaaaaaa     1500

aa                                                                    1502


<210>  1919
<211>  7614
<212>  DNA
<213>  homo sapiens

<400>  1919
aggccccgcc cgggccaacc gcctgcctgg tccgccctct gaccaagatc actccatgga       60

tgaaatgaca gctgtggtga aaattgaaaa aggagttggt ggcaataatg ggggcaatgg      120

taatggtggt ggtgcctttt cacaggctcg aagtagcagc acaggcagta gcagcagcac      180

tggaggagga gggcaggagt cccagccatc ccctttggct ctgctggcag caacttgcag      240

cagaattgag tcacccaatg agaacagcaa caactcccag ggcccgagtc agtcaggggg      300

aacaggtgag cttgacctca cagccacaca actttcacag ggtgccaatg gctggcagat      360

catctcttcc tcctctgggg ctacccctac ctcaaaggaa cagagtggca gcagtaccaa      420

tggcagcaat ggcagtgagt cttccaagaa tcgcacagtc tctggtgggc agtatgttgt      480

ggctgccgct cccaacttac agaaccagca agttctgaca ggactacctg gagtgatgcc      540

taatattcag tatcaagtaa tcccacagtt ccagaccgtt gatgggcaac agctgcagtt      600

tgctgccact ggggcccaag tgcagcagga tggttctggt caaatacaga tcataccagg      660

tgcaaaccaa cagattatca caaatcgagg aagtggaggc aacatcattg ctgctatgcc      720

aaacctactc cagcaggctg tccccctcca aggcctggct aataatgtac tctcaggaca      780

gactcagtat gtgaccaatg taccagtggc cctgaatggg aacatcacct tgctacctgt      840

caacagcgtt tctgcagcta ccttgactcc cagctctcag gcagtcacga tcagcagctc      900

tgggtcccag gagagtggct cacagcctgt cacctcaggg actaccatca gttctgccag      960

cttggtatca tcacaagcca gttccagctc ctttttcacc aatgccaata gctactcaac     1020

tactactacc accagcaaca tgggaattat gaactttact accagtggat catcagggac     1080

caactctcaa ggccagacac cccagagggt cagtgggcta caggggtctg atgctctgaa     1140

catccagcaa aaccagacat ctggaggctc attgcaagca ggccagcaaa aagaaggaga     1200

gcaaaaccag cagacacagc agcaacaaat tcttatccag cctcagctag ttcaaggggg     1260

acaggccctc caggccctcc aagcagcacc attgtcaggg cagaccttta caactcaagc     1320

catctcccag gaaaccctcc agaacctcca gcttcaggct gttccaaact ctggtcccat     1380

catcatccgg acaccaacag tggggcccaa tggacaggtc agttggcaga ctctacagct     1440

gcagaacctc caagttcaga acccacaagc ccaaacaatc accttagccc caatgcaggg     1500

tgtttccttg gggcagacca gcagcagcaa caccactctc acacccattg cctcagctgc     1560

ttccattcct gctggcacag tcactgtgaa tgctgctcaa ctctcctcca tgccaggcct     1620

ccagaccatt aacctcagtg cattgggtac ttcaggaatc caggtgcacc caattcaagg     1680

cctgccgttg gctatagcaa atgccccagg tgatcatgga gctcagcttg gtctccatgg     1740

ggctggtggt gatggaatac atgatgacac agcaggtgga gaggaaggag aaaacagccc     1800

agatgcccaa ccccaagccg gtcggaggac ccggcgggaa gcatgcacct gcccctactg     1860

taaagacagt gaaggaaggg gctcggggga tcctggcaaa aagaaacagc atatttgcca     1920

catccaaggc tgtgggaaag tgtatggcaa gacctctcac ctgcgggcac acttgcgctg     1980

gcatacaggc gagaggccat ttatgtgtac ctggtcatac tgtgggaaac gcttcacacg     2040

ttcggatgag ctacagaggc acaaacgtac acacacaggt gagaagaaat ttgcctgccc     2100

tgagtgtcct aagcgcttca tgaggagtga ccacctgtca aaacatatca agacccacca     2160

gaataagaag ggaggcccag gtgtagctct gagtgtgggc actttgcccc tggacagtgg     2220

ggcaggttca gaaggcagtg gcactgccac tccttcagcc cttattacca ccaatatggt     2280

agccatggag gccatctgtc cagagggcat tgcccgtctt gccaacagtg gcatcaacgt     2340

catgcaggtg gcagatctgc agtccattaa tatcagtggc aatggcttct gagatcaggc     2400

acccggggcc agagacatat gggccatacc ccttaacccc gggatgcaag gtagcatggg     2460

tccaagagac atggaagaga gagccatgaa gcattaaaat gcatggtgtt gagaagaatc     2520

aggagaggga tacaagagag gagatggggt cccggcaccc atctgtatca tcagtgcctc     2580

tttgaaggtg ggaaacatta gtgaaaattc tgttggtgcc acgctttgat gagcatttgt     2640

ttgaccccag tttcttctta cacttcttac cccagcctac ccttcctgca tttctcttct     2700

cagctcttcc atgatggatt cccccccctt tcctaaagcc atcatgcctt gataaatata     2760

tatgatcatt gaaatacttt ttaacaaaaa acagattcta tattattata tatatatata     2820

tatatataaa gatatataga gatgcattca caggggttgg ctgggaggag gaagaccatt     2880

ctgtgaccaa aataccttgg tcattttttt tatattgcct tatttcccta tggctgagcc     2940

ttgttgtgac acatcaagct tttctgtaga tgttgtcttg gcttcccacc agcttaagcg     3000

ttcatatgct ctgcttttag ttcatatata catacataat gtttttcctt tcttaatttt     3060

gtctttttgt ttgggatcag cttcttgcac tccttcccta actcaactgt tgccgtctca     3120

tcttctctca tctgatcact tcatgttttg tttttgttac tgcctggatg aggcacttct     3180

gtcaattttt tcaggacctt agttccagca gcagaatgga aaaatccttg aagcccaggc     3240

tgatgcttga agtaactgtg gagggagtgt tcaaaatact actgacgcag gcaccttctt     3300

ggcgctggag agtcaaaggc atctcccttc attagctgct ctgagcatca agaattagaa     3360

gtctttcagt ggaattgtac aagagtccct ttgaagataa taatcttggc tcagtttgta     3420

taaactgtca aattttcaaa taataggtag ggggctttca ctaggaaaat catgtgctca     3480

gaagaggaaa tgactcgtag tcaggttcag gagttagtgg agtatttgga ctttggtact     3540

gctgtcttcc aaggtagctc taagttttga tgtgtgggct tctgagttta tattctgaaa     3600

ggaaatacac ttcttttgaa catccccact aggttctttt ccattgtcaa taaggagcat     3660

cagccagtga atctgtttca ggtttccatt ctgcagaact cctccaaagc atgtgctagt     3720

ggcaagacag tggttcttat gatgttttcc cttaactttt ccttgtatgt tcttgggtgg     3780

ttcctaaggg aaagggaagc acatgatcat gggaatgata gcccagaaca aaaagaaatc     3840

ttgtcttacc acagtgtttt ataggagaga ttgggagaaa tcatcctgtt ttctctgtga     3900

cctgatttca gaagagactg atccaaaaat tataacggca gggaacctag tgcatttggc     3960

actgagattt aaatgcaacc agaattgtcc tcaaggccca gccataaaag cattgtctct     4020

ctcgaccttc tggtatcttg ttagagagct tttcactgtg aggaagtgtg gaaaaatagc     4080

tctgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgta atctgttagg ttggggatag     4140

gttttctgct agccaatatt aaaagagacc tgcaataaaa aaattaccct gatctgatag     4200

aaagcaagtg tttttgtatg tgtgggtgaa tgtgtgttca tgcccgtata tgtctacaca     4260

cagatgacaa attatatttg aaatcgttgg aaaataaatt cagatcaaaa tgcctttcag     4320

gcccattacc tagaaatcta tcttaaaacc tgggtatgtt cctaaggtca tttctttgct     4380

tatgctaaat taattacaat tatgaatgga ggatattcta ctgtactttt ttaaaaagaa     4440

actatttttg tgtttgaaag tgaaaccaac atccagatct atagcagagt ccttattctt     4500

ctcataaatc tttttacttt ggctacaaat agatgatggt atgattctat tatatatttt     4560

atataaaatc catccaaatt aagttttggg taagtgtgtt gtttaatctg aactatagta     4620

acttaatact ctaaacaata gttcactcca tttggtcctt tctccacaga tgtaattatg     4680

ttttcaactc aggaactatg gcaaggaact ttccccagat caaattctat taacgctgag     4740

atacaagtca tccatgcaca gccactatca taccctttat tctcactgaa aggcagaact     4800

cagaacctgt tattttatgt ctgtaatcat gtactttggc atcttttgga ggaaaggggc     4860

aggataactc actggaatgt acagtatttt gctagtgcat ttcaaggaat ggaatcttct     4920

ccagtatgaa attaccagat ataaaataat gtaatgatgc tgaggatata agcttttaga     4980

aggtaatttg atggtatttc tttctcgaat gaaaagctgc tggtttaccc tcaaccctat     5040

tcattagcat taccatgagt gaatttatat ctaattattt ccacttgccc tgttctcttc     5100

acaccaagga agctccagat ccagtatctt gtttggcctc aaaacagaag cagcttcttt     5160

tgtctcccag cagtagtgag ccactcagtc tcttccacag gaagtttgga gcctacattc     5220

cttgagtcag gagcttatta cagaaaaacc ccgtttccct gaacttttgg ctaacagaaa     5280

ttaatttaac tgacatgcat attgattctg aaattttttt cctaagtttt tttcattttt     5340

ttgaatgagt tttttaaatt ttttagatga ccaaaacttg cagggcaggg gatgcccaga     5400

agagtggtga gatagtaaaa cacttattcc ctcatccttt caggttttca ggttgcccat     5460

ttatattcat ttacatgtca tttgactgtc tcacttttta cccagaacag taacaaccca     5520

caccgtcttc cttcagggat ttccaactgg cactctgtgg gtgctacaca gaatgcaatt     5580

taatggatat ttctcagcct ggttcagaat aaattgatcc tttgatccca gaaagtatat     5640

actgaagtgt gggataaaga ttatgattag gggagggttg gagacaaaag ctgtaaatta     5700

ctatggctga tttatttcta ctatatacat atatattttt tgcttttgta tatcctatat     5760

aggaaactaa gcattgtatt ttttttaaca aatctaaaaa agcactatga actacaggtg     5820

tttgactttc aaaatatatt ttgtattgtt aatatcttca cattgtgtga atactggaag     5880

ctgcagatct ttgctaggac gcaataaatt tatatacttt ttgaggggtt cttctggggt     5940

gctaatcagg cccctgttat gcttaggggg agccctggtg ctacttgctt gaagttttca     6000

gtgtaagtac cctgatgcct tttggacctt gggatcagat caagagtttt ggagatcagg     6060

taccaaggaa ataaggacag tctagctgcc tcaagtgagg ggccctttgc atagctctcc     6120

ttccccctca ctgaagctgg gtagcctatt ggggttgaga gggaaaatgt gaaatctcag     6180

aatttatctc ccttagaaga gagccagtaa cttatgtaca aggatgaaag aaaggtcgca     6240

gcagtagctt tggggaaagg gaggaagata tggcacttct ccaaccccgg aaaacattgc     6300

ttttgaaaac tgctgataaa atatgagccg gttattactt ctgtttggga gactgtgctc     6360

tctgtggtgc ctctcttggc tctactccac agataccaga cctcttctaa gaggatgagc     6420

agaccagctt tgaggttgac ctgtttctct ttgtctgcct tcccaaaaca ccagccccca     6480

ggaagacatt aagcagcctt aagcttaaat tcctactccc tcttccaaat ttggctcact     6540

tgccttagat ccaaggcagg gaaaggaaaa gaaggggggt ctctggcttt attactcccc     6600

taagtcttta ctctgacttc cccaaaccca gaaagatttt ctccacagtg ttcatttgaa     6660

agaggagtat tttgtcccat tttccccttc ctcattatca aacagcccca gtcttccttg     6720

tctctgctaa gaaagtagag gcatgatgat ctgcctctca actgccctaa gtcctagcta     6780

agtatcaggg gaaaaaaaaa aaaaaaaagc ctaacaaatg ggattagact agggctgcaa     6840

gtagtgagga ttttgttgat acctctgctg ggatgtgtgc tttcccatat cttgccttca     6900

ggaattacac tgtgcctttt ccccagggat atgggctctg tctacccagt gctccagttt     6960

cccggtaact gctcttgaac attgtggaca agggcaggtc ttcatatttt tgatcatccc     7020

tttctcccag tgaaatccca tagcccttac ctagagtcta gggcacaaag acttcgggga     7080

agatacactg agattgacct gaggagacat ctacacacac cagtggcagc tgccccaggg     7140

cctgcttccc cttcctaagt ctgtcatcct ctggaaggga tgggtggtgc tccaatctct     7200

ggtgcctaaa aacccaagtt tatttctctc ttaacactgg caataaccag tccacaccac     7260

tgttgccttt taaaacctct taataatctc atgctgtgtt tgttttgatt ccaatccaat     7320

tatcaccagg gctgtgtggg taaatgcttt taaatgctct ctcatcttgt tcttccccct     7380

caccccccac tcttaggtat gtatgatgct aatcttgtcc ctaagtaagt ttcttcctgc     7440

tccttttgta tcttcctttc ttgtctttcc tcctaccttt tgtctcttgg tgttttggga     7500

cttttttttt tttttttttg gccttttgta caaagattag tttcaatgta gtctgtagcc     7560

tcctttgtaa accaattaaa aagtttttta ataaaaaaaa aaaaaaaaaa aaaa           7614


<210>  1920
<211>  3256
<212>  DNA
<213>  homo sapiens

<400>  1920
tttaaagaga gaggatcgta ttatagatac cgcgggggca aagctaaaaa aggggggagg       60

ggggaggaaa aaattcaaga agcagaaacc cctcgcggag ttttactgga agaaaaaaac      120

gggtctgaaa gattcctcct cttcatcatc atcaaccatc attcattcac taccttgaca      180

ttccgggctt tgattgacag ctggagtggc aaaaagccat gaaacacgac agttcggtta      240

catgtgggct gctgacgggc cgctcgtaac cttcagttcg ggggcttgac aatttttttc      300

ttctttttct tctttttctt ttctttcttt ttttttccaa ctgaggggaa gagaagagaa      360

agagggggaa aggaggaccg aagaggagga ggaggggagg ggggaggagg aggaggtgga      420

ggaggaggag gaagatcagg aggaggagga agaagaggaa aaaagagaaa aagaagaaat      480

atcacagaaa aaaaaattct tcgttgtcta gactgggctt tttttccccc ctaaaaaata      540

gcatattgga gaattgggag aagtctcttt ggtttggaaa aaaaaaaaag gaatcttcag      600

cctagatcac tttcttatcc ggactgggat attaaatata cgacacatcc aggagtttat      660

tggagcgcag actgatggcg caaaggtacg atgagctgcc ccattacggc gggatggacg      720

gagtaggggt tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg      780

ttcaccacct gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc      840

cgcaccccaa tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg      900

acaaggacgc gatctatggg cacccgttgt ttcctctgtt agctctggtc tttgagaagt      960

gcgagctggc gacctgcact ccccgggaac ctggagtggc tggcggagac gtctgctcct     1020

ccgactcctt caacgaggac atcgcggtct tcgccaagca ggttcgcgcc gaaaagccac     1080

ttttttcctc aaatccagag ctggacaatt tgatgataca agcaatacaa gtactaaggt     1140

ttcatctttt ggagttagaa aaggtccacg aactgtgcga taacttctgc caccgataca     1200

ttagctgttt gaaggggaaa atgcccatcg acctcgtcat tgatgaaaga gacggcagct     1260

ccaagtcaga tcatgaagaa ctttcaggct cctccacaaa tctcgctgac cataaccctt     1320

cttcttggcg agaccacgat gatgcaacct caacccactc agcaggcacc ccagggccct     1380

ccagtggggg ccatgcttcc cagagcggag acaacagcag tgagcaaggg gatggtttag     1440

acaacagtgt agcttcacct ggtacaggtg acgatgatga tccggataag gacaaaaaac     1500

gccagaagaa aagaggcatt ttccccaaag tagcaacaaa tatcatgaga gcatggctct     1560

tccagcatct cacacatccg tacccttccg aagagcagaa gaaacagtta gcgcaagaca     1620

caggacttac aattctccaa gtaaacaact ggtttattaa tgccagaaga agaatagtac     1680

agcccatgat tgaccagtca aatcgagcag tgagccaagg agcagcatat agtccagagg     1740

gtcagcccat ggggagcttt gtgttggatg gtcagcaaca catggggatc cggcctgcag     1800

gtttgcagag catgccaggg gactacgttt ctcagggtgg tcctatggga atgagtatgg     1860

cacagccaag ttacactcct ccccagatga ccccacaccc tactcaatta agacatggac     1920

ccccaatgca ttcatatttg ccaagccatc cccaccaccc agccatgatg atgcacggag     1980

gaccccctac ccaccctgga atgactatgt cagcacagag ccccacaatg ttaaattctg     2040

tagatcccaa tgttggcgga caggttatgg acattcatgc ccaatagtat aagggaactc     2100

aagggaaaag gaaacacacg caaaaactat tttaagactt tctgaacttt gaccagatgt     2160

tgacacttaa tatgaaattc cagacagctg tgattatttt ttacttttgt catttttcat     2220

caagcaacag aggaccaatg caacaagaac acaaatgtga aatcatgggc tgactgagac     2280

aattctgtcc atgtaaagat cctctggaaa aagactccga gagttataac tactgtagta     2340

taaatatagg aactaagtta aacttgtaca tttctgttga tcacgccgtt atgttgcctc     2400

aaatagtttt agaagagaaa aaaaaatata tccttgtttt ccacactatg tgtgttgttc     2460

ccaaaagaat gactgttttg gttcatcagt gaattcacca tccaggagag actgtggtat     2520

atattttaaa cctgttgggc caatgagaaa agaaccacac tggagatcat gatgaacttt     2580

tggctgaacc tcatcactcg aactccagct tcaagaatgt gttttcatgc ccggcctttg     2640

ttcctccata aatgtgtcct ttagtttcaa acagatcttt atagttcgtg cttcataagc     2700

caattcttat tattattttt gggggactct tcttcaaaga gcttgccaat gaagatttaa     2760

agacagagca ggagcttctt ccaggagttc tgagccttgg ttgtggacaa aacaatctta     2820

agttgggcag ctttcctcaa cacaaaaaaa agttattaat ggtcattgaa ccataactag     2880

gactttatca gaaactcaaa gcttggggga taaaaaggag caagagaata ctgtaacaaa     2940

cttcgtacag agttcggtct attaattgtt tcatgttaga tattctatgt gtttacctca     3000

attgaaaaaa aaaagaatgt ttttgctagt atcagatctg ctgtggaatt ggtattgtat     3060

gtccatgaat tcttcttttc tcagcacgtg ttcctcacta gaagaaaatg ctgttacctt     3120

taagctttgt caaatttaca ttaaaatact tgtatgagga ctgtgacgtt atgttaaaaa     3180

aaaaaaggtg ttaagtcaca aaaagcggta ataaatattt catttttgat tttttgttaa     3240

aaaaaaaaaa aaaaaa                                                     3256


<210>  1921
<211>  3277
<212>  DNA
<213>  homo sapiens

<400>  1921
tttaaagaga gaggatcgta ttatagatac cgcgggggca aagctaaaaa aggggggagg       60

ggggaggaaa aaattcaaga agcagaaacc cctcgcggag ttttactgga agaaaaaaac      120

gggtctgaaa gattcctcct cttcatcatc atcaaccatc attcattcac taccttgaca      180

ttccgggctt tgattgacag ctggagtggc aaaaagccat gaaacacgac agttcggtta      240

catgtgggct gctgacgggc cgctcgtaac cttcagttcg ggggcttgac aatttttttc      300

ttctttttct tctttttctt ttctttcttt ttttttccaa ctgaggggaa gagaagagaa      360

agagggggaa aggaggaccg aagaggagga ggaggggagg ggggaggagg aggaggtgga      420

ggaggaggag gaagatcagg aggaggagga agaagaggaa aaaagagaaa aagaagaaat      480

atcacagaaa aaaaaattct tcgttgtcta gactgggctt tttttccccc ctaaaaaata      540

gcatattgga gaattgggag aagtctcttt ggtttggaaa aaaaaaaaag gaatcttcag      600

cctagatcac tttcttatcc ggactgggat attaaatata cgacacatcc aggagtttat      660

tggagcgcag actgatggcg caaaggtacg atgagctgcc ccattacggc gggatggacg      720

gagtaggggt tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg      780

ttcaccacct gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc      840

cgcaccccaa tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg      900

acaaggacgc gatctatggg cacccgttgt ttcctctgtt agctctggtc tttgagaagt      960

gcgagctggc gacctgcact ccccgggaac ctggagtggc tggcggagac gtctgctcct     1020

ccgactcctt caacgaggac atcgcggtct tcgccaagca ggttcgcgcc gaaaagccac     1080

ttttttcctc aaatccagag ctggacaatt tgatgataca agcaatacaa gtactaaggt     1140

ttcatctttt ggagttagaa aaggtccacg aactgtgcga taacttctgc caccgataca     1200

ttagctgttt gaaggggaaa atgcccatcg acctcgtcat tgatgaaaga gacggcagct     1260

ccaagtcaga tcatgaagaa ctttcaggct cctccacaaa tctcgctgac cataaccctt     1320

cttcttggcg agaccacgat gatgcaacct caacccactc agcaggcacc ccagggccct     1380

ccagtggggg ccatgcttcc cagagcggag acaacagcag tgagcaaggg gatggtttag     1440

acaacagtgt agcttcacct ggtacaggtg acgatgatga tccggataag gacaaaaaac     1500

gccagaagaa aagaggcatt ttccccaaag tagcaacaaa tatcatgaga gcatggctct     1560

tccagcatct cacacatccg tacccttccg aagagcagaa gaaacagtta gcgcaagaca     1620

caggacttac aattctccaa gtaaacaact ggtttattaa tgccagaaga agaatagtac     1680

agcccatgat tgaccagtca aatcgagcag gttttcttct tgatccttca gtgagccaag     1740

gagcagcata tagtccagag ggtcagccca tggggagctt tgtgttggat ggtcagcaac     1800

acatggggat ccggcctgca ggtttgcaga gcatgccagg ggactacgtt tctcagggtg     1860

gtcctatggg aatgagtatg gcacagccaa gttacactcc tccccagatg accccacacc     1920

ctactcaatt aagacatgga cccccaatgc attcatattt gccaagccat ccccaccacc     1980

cagccatgat gatgcacgga ggacccccta cccaccctgg aatgactatg tcagcacaga     2040

gccccacaat gttaaattct gtagatccca atgttggcgg acaggttatg gacattcatg     2100

cccaatagta taagggaact caagggaaaa ggaaacacac gcaaaaacta ttttaagact     2160

ttctgaactt tgaccagatg ttgacactta atatgaaatt ccagacagct gtgattattt     2220

tttacttttg tcatttttca tcaagcaaca gaggaccaat gcaacaagaa cacaaatgtg     2280

aaatcatggg ctgactgaga caattctgtc catgtaaaga tcctctggaa aaagactccg     2340

agagttataa ctactgtagt ataaatatag gaactaagtt aaacttgtac atttctgttg     2400

atcacgccgt tatgttgcct caaatagttt tagaagagaa aaaaaaatat atccttgttt     2460

tccacactat gtgtgttgtt cccaaaagaa tgactgtttt ggttcatcag tgaattcacc     2520

atccaggaga gactgtggta tatattttaa acctgttggg ccaatgagaa aagaaccaca     2580

ctggagatca tgatgaactt ttggctgaac ctcatcactc gaactccagc ttcaagaatg     2640

tgttttcatg cccggccttt gttcctccat aaatgtgtcc tttagtttca aacagatctt     2700

tatagttcgt gcttcataag ccaattctta ttattatttt tgggggactc ttcttcaaag     2760

agcttgccaa tgaagattta aagacagagc aggagcttct tccaggagtt ctgagccttg     2820

gttgtggaca aaacaatctt aagttgggca gctttcctca acacaaaaaa aagttattaa     2880

tggtcattga accataacta ggactttatc agaaactcaa agcttggggg ataaaaagga     2940

gcaagagaat actgtaacaa acttcgtaca gagttcggtc tattaattgt ttcatgttag     3000

atattctatg tgtttacctc aattgaaaaa aaaaagaatg tttttgctag tatcagatct     3060

gctgtggaat tggtattgta tgtccatgaa ttcttctttt ctcagcacgt gttcctcact     3120

agaagaaaat gctgttacct ttaagctttg tcaaatttac attaaaatac ttgtatgagg     3180

actgtgacgt tatgttaaaa aaaaaaaggt gttaagtcac aaaaagcggt aataaatatt     3240

tcatttttga ttttttgtta aaaaaaaaaa aaaaaaa                              3277


<210>  1922
<211>  3352
<212>  DNA
<213>  homo sapiens

<400>  1922
tttaaagaga gaggatcgta ttatagatac cgcgggggca aagctaaaaa aggggggagg       60

ggggaggaaa aaattcaaga agcagaaacc cctcgcggag ttttactgga agaaaaaaac      120

gggtctgaaa gattcctcct cttcatcatc atcaaccatc attcattcac taccttgaca      180

ttccgggctt tgattgacag ctggagtggc aaaaagccat gaaacacgac agttcggtta      240

catgtgggct gctgacgggc cgctcgtaac cttcagttcg ggggcttgac aatttttttc      300

ttctttttct tctttttctt ttctttcttt ttttttccaa ctgaggggaa gagaagagaa      360

agagggggaa aggaggaccg aagaggagga ggaggggagg ggggaggagg aggaggtgga      420

ggaggaggag gaagatcagg aggaggagga agaagaggaa aaaagagaaa aagaagaaat      480

atcacagaaa aaaaaattct tcgttgtcta gactgggctt tttttccccc ctaaaaaata      540

gcatattgga gaattgggag aagtctcttt ggtttggaaa aaaaaaaaag gaatcttcag      600

cctagatcac tttcttatcc ggactgggat attaaatata cgacacatcc aggagtttat      660

tggagcgcag actgatggcg caaaggtacg atgagctgcc ccattacggc gggatggacg      720

gagtaggggt tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg      780

ttcaccacct gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc      840

cgcaccccaa tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg      900

acaaggacgc gatctatggg cacccgttgt ttcctctgtt agctctggtc tttgagaagt      960

gcgagctggc gacctgcact ccccgggaac ctggagtggc tggcggagac gtctgctcct     1020

ccgactcctt caacgaggac atcgcggtct tcgccaagca ggttcgcgcc gaaaagccac     1080

ttttttcctc aaatccagag ctggacaatt tgatgataca agcaatacaa gtactaaggt     1140

ttcatctttt ggagttagaa aaggtccacg aactgtgcga taacttctgc caccgataca     1200

ttagctgttt gaaggggaaa atgcccatcg acctcgtcat tgatgaaaga gacggcagct     1260

ccaagtcaga tcatgaagaa ctttcaggct cctccacaaa tctcgctgac cataaccctt     1320

cttcttggcg agaccacgat gatgcaacct caacccactc agcaggcacc ccagggccct     1380

ccagtggggg ccatgcttcc cagagcggag acaacagcag tgagcaaggg gatggtttag     1440

acaacagtgt agcttcacct ggtacaggtg acgatgatga tccggataag gacaaaaaac     1500

gccagaagaa aagaggcatt ttccccaaag tagcaacaaa tatcatgaga gcatggctct     1560

tccagcatct cacacatccg tacccttccg aagagcagaa gaaacagtta gcgcaagaca     1620

caggacttac aattctccaa gtaaacaact ggtttattaa tgccagaaga agaatagtac     1680

agcccatgat tgaccagtca aatcgagcag tgagccaagg agcagcatat agtccagagg     1740

gtcagcccat ggggagcttt gtgttggatg gtcagcaaca catggggatc cggcctgcag     1800

gacctatgag tggaatgggc atgaatatgg gcatggatgg gcaatggcac tacatgtaac     1860

cttcatcatg taaagcaatc gcaaagcaag ggggaagttt gcagagcatg ccaggggact     1920

acgtttctca gggtggtcct atgggaatga gtatggcaca gccaagttac actcctcccc     1980

agatgacccc acaccctact caattaagac atggaccccc aatgcattca tatttgccaa     2040

gccatcccca ccacccagcc atgatgatgc acggaggacc ccctacccac cctggaatga     2100

ctatgtcagc acagagcccc acaatgttaa attctgtaga tcccaatgtt ggcggacagg     2160

ttatggacat tcatgcccaa tagtataagg gaactcaagg gaaaaggaaa cacacgcaaa     2220

aactatttta agactttctg aactttgacc agatgttgac acttaatatg aaattccaga     2280

cagctgtgat tattttttac ttttgtcatt tttcatcaag caacagagga ccaatgcaac     2340

aagaacacaa atgtgaaatc atgggctgac tgagacaatt ctgtccatgt aaagatcctc     2400

tggaaaaaga ctccgagagt tataactact gtagtataaa tataggaact aagttaaact     2460

tgtacatttc tgttgatcac gccgttatgt tgcctcaaat agttttagaa gagaaaaaaa     2520

aatatatcct tgttttccac actatgtgtg ttgttcccaa aagaatgact gttttggttc     2580

atcagtgaat tcaccatcca ggagagactg tggtatatat tttaaacctg ttgggccaat     2640

gagaaaagaa ccacactgga gatcatgatg aacttttggc tgaacctcat cactcgaact     2700

ccagcttcaa gaatgtgttt tcatgcccgg cctttgttcc tccataaatg tgtcctttag     2760

tttcaaacag atctttatag ttcgtgcttc ataagccaat tcttattatt atttttgggg     2820

gactcttctt caaagagctt gccaatgaag atttaaagac agagcaggag cttcttccag     2880

gagttctgag ccttggttgt ggacaaaaca atcttaagtt gggcagcttt cctcaacaca     2940

aaaaaaagtt attaatggtc attgaaccat aactaggact ttatcagaaa ctcaaagctt     3000

gggggataaa aaggagcaag agaatactgt aacaaacttc gtacagagtt cggtctatta     3060

attgtttcat gttagatatt ctatgtgttt acctcaattg aaaaaaaaaa gaatgttttt     3120

gctagtatca gatctgctgt ggaattggta ttgtatgtcc atgaattctt cttttctcag     3180

cacgtgttcc tcactagaag aaaatgctgt tacctttaag ctttgtcaaa tttacattaa     3240

aatacttgta tgaggactgt gacgttatgt taaaaaaaaa aaggtgttaa gtcacaaaaa     3300

gcggtaataa atatttcatt tttgattttt tgttaaaaaa aaaaaaaaaa aa             3352


<210>  1923
<211>  3390
<212>  DNA
<213>  homo sapiens

<400>  1923
agaaggggaa acaggaatcg attaggaata aaggattata atccactttc cttctgagga       60

aaagctggga accttctcat tttgccttat gaaaactaag ctgaatcgac tgctgccaaa      120

catctattag gcaaaattgg cctcttgccc atgatttgac tttccagcac agccagttct      180

ttttctcctc tgcagctgat tggctctgga gtgtggccag aagcctctct cctgcaatta      240

aaggagtcgg gtctctaact gttgatctgt ttttttccct tctgagcaat ggagcttacc      300

atctttatcc tgagactggc catttacatc ctgacatttc ccttgtacct gctgaacttt      360

ctgggcttgt ggagctggat atgcaaaaaa tggttcccct acttcttggt gaggttcact      420

gtgatataca acgaacagat ggcaagcaag aagcgggagc tcttcagtaa cctgcaggag      480

tttgcgggcc cctccgggaa actctccctg ctggaagtgg gctgtggcac gggggccaac      540

ttcaagttct acccacctgg gtgcagggtg acctgtattg accccaaccc caactttgag      600

aagtttttga tcaagagcat tgcagagaac cgacacctgc agtttgagcg ctttgtggta      660

gctgccgggg agaacatgca ccaggtggct gatggctctg tggatgtggt ggtctgcacc      720

ctggtgctgt gctctgtgaa gaaccaggag cggattctcc gcgaggtgtg cagagtgctg      780

agaccgggag gggctttcta tttcatggag catgtggcag ctgagtgttc gacttggaat      840

tacttctggc aacaagtcct ggatcctgcc tggcaccttc tgtttgatgg gtgcaacctg      900

accagagaga gctggaaggc cctggagcgg gccagcttct ctaagctgaa gctgcagcac      960

atccaggccc cactgtcctg ggagttggtg cgccctcata tctatggata tgctgtgaaa     1020

tagtgtgagc tggcagttaa gagctgaatg gctcaaagaa tttaaagctt cagttttaca     1080

tttaaaatgc taagtgggag aagagaaacc ttttttttgg ggggcggttt ttttggtttg     1140

ttgttggttt tttttttttt tttggcggga agaaagagtt ttgctcttgt tgcccaggct     1200

ggagtgcaat gacgtgatct ccgctcactg caacctccac ctcgcgggtt taagcgattc     1260

ttctgcctca gcctccctag tagctgggat tacaggtgcc caccaccatg cccagctaat     1320

ttgtattttt agttgagaca gggtttcact acgttggcca ggctggtctt gaactcctga     1380

tctcaggcaa tccacccacc tcagcctccc aaagtgctgg gatgacaggc gtgagcaacc     1440

gcacccagct taaggttttt ttgttttgtt ttgagacgga gttttcgctc ttgttgccca     1500

ggctggagtg caatgctgtg atctcagctt accacaacct ccacctcccg ggttcaagtg     1560

attcacctgc ctcagcctcc tgagtagctg gtattacagg catgcgtcac cacgccggct     1620

aattttgtac ttttagtaga gatggtgttt ccccacgttg gtcagtctgg tctcaaattc     1680

ctgacctcag gtgatctgcc tgcctcggcc tcccaaagtg ctgtgattac agacgtcagc     1740

caccatgcct ggcctgaaac cttttttagg taaagttgaa ttccatcctt aaaagtttct     1800

gttatatcct atttagccat tttctattgt ctcccaaaga attcacatca aaaaaacagc     1860

tttgaactcc cccttcaaag gaaacagtcg actttcataa ttagcatcta ccattatccc     1920

caaatcttat tttattcatt gacttgaaat tttttccaat tgcttttttt tttttttttt     1980

taaggttaag agcagaggtt tactaggcca aagaaagaga atagctctct gttgcagaga     2040

ggggtcctgg agaaatgggt taccccagtt gtcttattta aatggttacc catcagattt     2100

taattttatc ttctctttga gagcttggta ataagaagca cttaaatcac tccaaagaag     2160

actttaaaaa gggagcagtg aaaaggtctt aataatttat tgattgaatt aagaaatact     2220

agctaattaa gaatctgagt ctaaacagca cagatttttt ctttctgctt ttaaattgtg     2280

ttttaaaaaa agagacaggg ggctgggcgt ggtggctcac gcctgtaatc ctagcacttt     2340

gggaggccga ggcgggtgga tcacgaggta ggagttaaag accagcctgg ccaacatggc     2400

aaaaccctac taaagataca aaaaaaaaaa aaaattagcc aggcgtggtg gtgggtgcct     2460

gtaatcccag gtacttggaa ggctgaggca ggagaatctc ttgaacccag aaggcgaagg     2520

ttgcagtgaa ccgagatcat gccattgtac tctagcctgg gtgacaagag caagactccg     2580

tctcaaaaaa aaaaaaaaaa aaaaaaagaa gtagagacag ggagacaggg tctcactgtg     2640

ttgcctaggc cggtcttgaa ctcctgggct caagtgattc tcccaccttg acctcctaaa     2700

ttgttgggat tacaggtgtg agacagtgca cctggccgaa atagctcaag tttctgaaaa     2760

acaaatctga atctatttgt tattcttagc gtcactggtc tggctttcag aattaacata     2820

caaggttgcc acacctagtt ctgcccagct ttatgtcttt tattccagta ttccaccaaa     2880

gtttgttttc ctgcattcca gttctcaagt cttaagataa agattgtact tgacagttta     2940

gtatatccat aaaactattt gaggtggtta aggttcttgg gttcattttc cttaatactt     3000

tgctgaatat tgtagattgt aggcaatgaa aaagtctact aaattaggaa aaccttgaat     3060

aattaggtat cctaggtaag agcccctaaa catcaagcaa tctgtgagtc tgtaaagaaa     3120

taaatatttt ttggattatt cttatctaat tccacccctg ttggaagatg atttctttgt     3180

tctttgcaac tatggaagct gtgaaaatca tcacaagtgc ctctgaaagc gagtgttagg     3240

ttggttagag ggtttaatat tttctgcaat ggtttgtagg aattttaata aatgtagtat     3300

attttctgag atgattttgt aaaagtacta ttttaaatat caaatcaacc aataaattca     3360

catttgtgtt aggaacagaa atatggttta                                      3390


<210>  1924
<211>  2259
<212>  DNA
<213>  homo sapiens

<400>  1924
agaaggagcg aagctctggc ccggcgtgta gcgggcgcac tacggggacg ctgggccggg       60

caccgggctg tgtggagaag tgagcgcgct cgtctgaccc ccgtgcccgc caccccgagc      120

cactaacggc gatctcccaa ggcctgcccg aggcctctgt cctctgtcct cagccccgca      180

gcggcaacgt cttgcactcg gcgagctcgc cgctcccgac cctcccgcgc ccccgccctg      240

ccgcgctgct ccccgcccag ccgcgggtct gtggtccaag ccgccccgaa gcagcccgaa      300

caagatcact caaggtgaag gataatctac taataccagc actttgaatg aaaatttgtt      360

tctctgccac aaactgaaca tctttttttt tttttttttt ttttggtggg ggagttgaaa      420

cctaattttg tggcgtagca gctatgcagc ttgaaatcca agtagcacta aattttatta      480

tttcgtattt gtacaataag cttcccagga gacgtgtcaa catttttggt gaagaacttg      540

aaagacttct taagaagaaa tatgaagggc actggtatcc tgaaaagcca tacaaaggat      600

cggggtttag atgtatacac ataggggaga aagtggaccc agtgattgaa caagcatcca      660

aagagagtgg tttggacatt gatgatgttc gtggcaatct gccacaggat cttagtgttt      720

ggatcgaccc atttgaggtt tcttaccaaa ttggtgaaaa gggaccagtg aaggtgcttt      780

acgtggatga taataatgaa aatggatgtg agttggataa ggagatcaaa aacagcttta      840

acccagaggc ccaggttttt atgcccataa gtgacccagc ctcatcagtg tccagctctc      900

catcgcctcc ttttggtcac tctgctgctg taagccctac cttcatgccc cggtccactc      960

agcctttaac ctttaccact gccacttttg ctgccaccaa gttcggctct accaaaatga     1020

agaatagtgg ccgtagcaac aaggttgcac gtacttctcc catcaacctc ggcttgaatg     1080

tgaatgacct cttgaagcag aaagccatct cttcctcaat gcactctctg tatgggcttg     1140

gcttgggtag ccagcagcag ccacagcaac agcagcagcc agcccagccg ccaccgccac     1200

caccaccacc acagcagcaa caacagcaga aaacctctgc tctttctcct aatgccaagg     1260

aatttatttt tcctaatatg cagggtcaag gtagtagtac caatggaatg ttcccaggtg     1320

acagccccct taacctcagt cctctccagt acagtaatgc ctttgatgtg tttgcagcct     1380

atggaggcct caatgagaaa tcttttgtag atggcttgaa ttttagctta aataacatgc     1440

agtattctaa ccagcaattc cagcctgtta tggctaacta aaaaaaagaa aatgtatcgt     1500

acaagttaaa atgcacgggc ccaaggggga tttttttttt cacctccttg agaatttttt     1560

tttttaagct tatagtaagg atacattcaa gcttggttaa aaaaataata ataaaacatg     1620

catcattttt catttgccaa ccaagcacaa agttatttta tactgactgt atattttaaa     1680

gtatactctc agatatggcc tcttacagta tttaagatat agcaaggaca tggctgattt     1740

ttttttataa aaattggcac taataagtgg gtttattggt cttttctaat tgtataattt     1800

aatttagtac aaagtttgta aaatatcaga ggatatatat atattgtttc tacgacatgg     1860

tattgcattt atatcttttt actacagtga tctgtgacag cagcagcttc atgttgtatt     1920

ttttttactg aaattgtaaa atatccatct taaagacatc aactattcta aaaattgtgt     1980

acaggatatt cctttagtgg tggaattaaa atgtacgaat acttgctttt tcaaaaaaat     2040

gtattttctg ttaaaagttt aaagattttt gctatatatt atggaagaaa aatgtaatcg     2100

taaatattaa ttttgtacct atattgtgca atacttgaaa aaaacggtat aaaagtattt     2160

tgagtcagtg tcttacatgt taagagggac tgaaatagtt tatattaagt ttgtattaaa     2220

attctttaaa attaaaaaaa aaaaaaaaaa aaaaaaaaa                            2259


<210>  1925
<211>  2259
<212>  DNA
<213>  homo sapiens

<400>  1925
agaaggagcg aagctctggc ccggcgtgta gcgggcgcac tacggggacg ctgggccggg       60

caccgggctg tgtggagaag tgagcgcgct cgtctgaccc ccgtgcccgc caccccgagc      120

cactaacggc gatctcccaa ggcctgcccg aggcctctgt cctctgtcct cagccccgca      180

gcggcaacgt cttgcactcg gcgagctcgc cgctcccgac cctcccgcgc ccccgccctg      240

ccgcgctgct ccccgcccag ccgcgggtct gtggtccaag ccgccccgaa gcagcccgaa      300

caagatcact caaggtgaag gataatctac taataccagc actttgaatg aaaatttgtt      360

tctctgccac aaactgaaca tctttttttt tttttttttt ttttggtggg ggagttgaaa      420

cctaattttg tggcgtagca gctatgcagc ttgaaatcca agtagcacta aattttatta      480

tttcgtattt gtacaataag cttcccagga gacgtgtcaa catttttggt gaagaacttg      540

aaagacttct taagaagaaa tatgaagggc actggtatcc tgaaaagcca tacaaaggat      600

cggggtttag atgtatacac ataggggaga aagtggaccc agtgattgaa caagcatcca      660

aagagagtgg tttggacatt gatgatgttc gtggcaatct gccacaggat cttagtgttt      720

ggatcgaccc atttgaggtt tcttaccaaa ttggtgaaaa gggaccagtg aaggtgcttt      780

acgtggatga taataatgaa aatggatgtg agttggataa ggagatcaaa aacagcttta      840

acccagaggc ccaggttttt atgcccataa gtgacccagc ctcatcagtg tccagctctc      900

catcgcctcc ttttggtcac tctgctgctg taagccctac cttcatgccc cggtccactc      960

agcctttaac ctttaccact gccacttttg ctgccaccaa gttcggctct accaaaatga     1020

agaatagtgg ccgtagcaac aaggttgcac gtacttctcc catcaacctc ggcttgaatg     1080

tgaatgacct cttgaagcag aaagccatct cttcctcaat gcactctctg tatgggcttg     1140

gcttgggtag ccagcagcag ccacagcaac agcagcagcc agcccagccg ccaccgccac     1200

caccaccacc acagcagcaa caacagcaga aaacctctgc tctttctcct aatgccaagg     1260

aatttatttt tcctaatatg cagggtcaag gtagtagtac caatggaatg ttcccaggtg     1320

acagccccct taacctcagt cctctccagt acagtaatgc ctttgatgtg tttgcagcct     1380

atggaggcct caatgagaaa tcttttgtag atggcttgaa ttttagctta aataacatgc     1440

agtattctaa ccagcaattc cagcctgtta tggctaacta aaaaaaagaa aatgtatcgt     1500

acaagttaaa atgcacgggc ccaaggggga tttttttttt cacctccttg agaatttttt     1560

tttttaagct tatagtaagg atacattcaa gcttggttaa aaaaataata ataaaacatg     1620

catcattttt catttgccaa ccaagcacaa agttatttta tactgactgt atattttaaa     1680

gtatactctc agatatggcc tcttacagta tttaagatat agcaaggaca tggctgattt     1740

ttttttataa aaattggcac taataagtgg gtttattggt cttttctaat tgtataattt     1800

aatttagtac aaagtttgta aaatatcaga ggatatatat atattgtttc tacgacatgg     1860

tattgcattt atatcttttt actacagtga tctgtgacag cagcagcttc atgttgtatt     1920

ttttttactg aaattgtaaa atatccatct taaagacatc aactattcta aaaattgtgt     1980

acaggatatt cctttagtgg tggaattaaa atgtacgaat acttgctttt tcaaaaaaat     2040

gtattttctg ttaaaagttt aaagattttt gctatatatt atggaagaaa aatgtaatcg     2100

taaatattaa ttttgtacct atattgtgca atacttgaaa aaaacggtat aaaagtattt     2160

tgagtcagtg tcttacatgt taagagggac tgaaatagtt tatattaagt ttgtattaaa     2220

attctttaaa attaaaaaaa aaaaaaaaaa aaaaaaaaa                            2259


<210>  1926
<211>  5753
<212>  DNA
<213>  homo sapiens

<400>  1926
gattggctgg tctgcttcgg gcgggctaaa ggaaggttca agtggagctc tcctaaccga       60

cgcgcgtctg tggagaagcg gcttggtcgg gggtggtctc gtggggtcct gcctgtttag      120

tcgctttcag ggttcttgag ccccttcacg accgtcacca tggaagtgtc accattgcag      180

cctgtaaatg aaaatatgca agtcaacaaa ataaagaaaa atgaagatgc taagaaaaga      240

ctgtctgttg aaagaatcta tcaaaagaaa acacaattgg aacatatttt gctccgccca      300

gacacctaca ttggttctgt ggaattagtg acccagcaaa tgtgggttta cgatgaagat      360

gttggcatta actataggga agtcactttt gttcctggtt tgtacaaaat ctttgatgag      420

attctagtta atgctgcgga caacaaacaa agggacccaa aaatgtcttg tattagagtc      480

acaattgatc cggaaaacaa tttaattagt atatggaata atggaaaagg tattcctgtt      540

gttgaacaca aagttgaaaa gatgtatgtc ccagctctca tatttggaca gctcctaact      600

tctagtaact atgatgatga tgaaaagaaa gtgacaggtg gtcgaaatgg ctatggagcc      660

aaattgtgta acatattcag taccaaattt actgtggaaa cagccagtag agaatacaag      720

aaaatgttca aacagacatg gatggataat atgggaagag ctggtgagat ggaactcaag      780

cccttcaatg gagaagatta tacatgtatc acctttcagc ctgatttgtc taagtttaaa      840

atgcaaagcc tggacaaaga tattgttgca ctaatggtca gaagagcata tgatattgct      900

ggatccacca aagatgtcaa agtctttctt aatggaaata aactgccagt aaaaggattt      960

cgtagttatg tggacatgta tttgaaggac aagttggatg aaactggtaa ctccttgaaa     1020

gtaatacatg aacaagtaaa ccacaggtgg gaagtgtgtt taactatgag tgaaaaaggc     1080

tttcagcaaa ttagctttgt caacagcatt gctacatcca agggtggcag acatgttgat     1140

tatgtagctg atcagattgt gactaaactt gttgatgttg tgaagaagaa gaacaagggt     1200

ggtgttgcag taaaagcaca tcaggtgaaa aatcacatgt ggatttttgt aaatgcctta     1260

attgaaaacc caacctttga ctctcagaca aaagaaaaca tgactttaca acccaagagc     1320

tttggatcaa catgccaatt gagtgaaaaa tttatcaaag ctgccattgg ctgtggtatt     1380

gtagaaagca tactaaactg ggtgaagttt aaggcccaag tccagttaaa caagaagtgt     1440

tcagctgtaa aacataatag aatcaaggga attcccaaac tcgatgatgc caatgatgca     1500

gggggccgaa actccactga gtgtacgctt atcctgactg agggagattc agccaaaact     1560

ttggctgttt caggccttgg tgtggttggg agagacaaat atggggtttt ccctcttaga     1620

ggaaaaatac tcaatgttcg agaagcttct cataagcaga tcatggaaaa tgctgagatt     1680

aacaatatca tcaagattgt gggtcttcag tacaagaaaa actatgaaga tgaagattca     1740

ttgaagacgc ttcgttatgg gaagataatg attatgacag atcaggacca agatggttcc     1800

cacatcaaag gcttgctgat taattttatc catcacaact ggccctctct tctgcgacat     1860

cgttttctgg aggaatttat cactcccatt gtaaaggtat ctaaaaacaa gcaagaaatg     1920

gcattttaca gccttcctga atttgaagag tggaagagtt ctactccaaa tcataaaaaa     1980

tggaaagtca aatattacaa aggtttgggc accagcacat caaaggaagc taaagaatac     2040

tttgcagata tgaaaagaca tcgtatccag ttcaaatatt ctggtcctga agatgatgct     2100

gctatcagcc tggcctttag caaaaaacag atagatgatc gaaaggaatg gttaactaat     2160

ttcatggagg atagaagaca acgaaagtta cttgggcttc ctgaggatta cttgtatgga     2220

caaactacca catatctgac atataatgac ttcatcaaca aggaacttat cttgttctca     2280

aattctgata acgagagatc tatcccttct atggtggatg gtttgaaacc aggtcagaga     2340

aaggttttgt ttacttgctt caaacggaat gacaagcgag aagtaaaggt tgcccaatta     2400

gctggatcag tggctgaaat gtcttcttat catcatggtg agatgtcact aatgatgacc     2460

attatcaatt tggctcagaa ttttgtgggt agcaataatc taaacctctt gcagcccatt     2520

ggtcagtttg gtaccaggct acatggtggc aaggattctg ctagtccacg atacatcttt     2580

acaatgctca gctctttggc tcgattgtta tttccaccaa aagatgatca cacgttgaag     2640

tttttatatg atgacaacca gcgtgttgag cctgaatggt acattcctat tattcccatg     2700

gtgctgataa atggtgctga aggaatcggt actgggtggt cctgcaaaat ccccaacttt     2760

gatgtgcgtg aaattgtaaa taacatcagg cgtttgatgg atggagaaga acctttgcca     2820

atgcttccaa gttacaagaa cttcaagggt actattgaag aactggctcc aaatcaatat     2880

gtgattagtg gtgaagtagc tattcttaat tctacaacca ttgaaatctc agagcttccc     2940

gtcagaacat ggacccagac atacaaagaa caagttctag aacccatgtt gaatggcacc     3000

gagaagacac ctcctctcat aacagactat agggaatacc atacagatac cactgtgaaa     3060

tttgttgtga agatgactga agaaaaactg gcagaggcag agagagttgg actacacaaa     3120

gtcttcaaac tccaaactag tctcacatgc aactctatgg tgctttttga ccacgtaggc     3180

tgtttaaaga aatatgacac ggtgttggat attctaagag acttttttga actcagactt     3240

aaatattatg gattaagaaa agaatggctc ctaggaatgc ttggtgctga atctgctaaa     3300

ctgaataatc aggctcgctt tatcttagag aaaatagatg gcaaaataat cattgaaaat     3360

aagcctaaga aagaattaat taaagttctg attcagaggg gatatgattc ggatcctgtg     3420

aaggcctgga aagaagccca gcaaaaggtt ccagatgaag aagaaaatga agagagtgac     3480

aacgaaaagg aaactgaaaa gagtgactcc gtaacagatt ctggaccaac cttcaactat     3540

cttcttgata tgcccctttg gtatttaacc aaggaaaaga aagatgaact ctgcaggcta     3600

agaaatgaaa aagaacaaga gctggacaca ttaaaaagaa agagtccatc agatttgtgg     3660

aaagaagact tggctacatt tattgaagaa ttggaggctg ttgaagccaa ggaaaaacaa     3720

gatgaacaag tcggacttcc tgggaaaggg gggaaggcca aggggaaaaa aacacaaatg     3780

gctgaagttt tgccttctcc gcgtggtcaa agagtcattc cacgaataac catagaaatg     3840

aaagcagagg cagaaaagaa aaataaaaag aaaattaaga atgaaaatac tgaaggaagc     3900

cctcaagaag atggtgtgga actagaaggc ctaaaacaaa gattagaaaa gaaacagaaa     3960

agagaaccag gtacaaagac aaagaaacaa actacattgg catttaagcc aatcaaaaaa     4020

ggaaagaaga gaaatccctg gtctgattca gaatcagata ggagcagtga cgaaagtaat     4080

tttgatgtcc ctccacgaga aacagagcca cggagagcag caacaaaaac aaaattcaca     4140

atggatttgg attcagatga agatttctca gattttgatg aaaaaactga tgatgaagat     4200

tttgtcccat cagatgctag tccacctaag accaaaactt ccccaaaact tagtaacaaa     4260

gaactgaaac cacagaaaag tgtcgtgtca gaccttgaag ctgatgatgt taagggcagt     4320

gtaccactgt cttcaagccc tcctgctaca catttcccag atgaaactga aattacaaac     4380

ccagttccta aaaagaatgt gacagtgaag aagacagcag caaaaagtca gtcttccacc     4440

tccactaccg gtgccaaaaa aagggctgcc ccaaaaggaa ctaaaaggga tccagctttg     4500

aattctggtg tctctcaaaa gcctgatcct gccaaaacca agaatcgccg caaaaggaag     4560

ccatccactt ctgatgattc tgactctaat tttgagaaaa ttgtttcgaa agcagtcaca     4620

agcaagaaat ccaaggggga gagtgatgac ttccatatgg actttgactc agctgtggct     4680

cctcgggcaa aatctgtacg ggcaaagaaa cctataaagt acctggaaga gtcagatgaa     4740

gatgatctgt tttaaaatgt gaggcgatta ttttaagtaa ttatcttacc aagcccaaga     4800

ctggttttaa agttacctga agctcttaac ttcctcccct ctgaatttag tttggggaag     4860

gtgtttttag tacaagacat caaagtgaag taaagcccaa gtgttcttta gctttttata     4920

atactgtcta aatagtgacc atctcatggg cattgttttc ttctctgctt tgtctgtgtt     4980

ttgagtctgc tttcttttgt ctttaaaacc tgatttttaa gttcttctga actgtagaaa     5040

tagctatctg atcacttcag cgtaaagcag tgtgtttatt aaccatccac taagctaaaa     5100

ctagagcagt ttgatttaaa agtgtcactc ttcctccttt tctactttca gtagatatga     5160

gatagagcat aattatctgt tttatcttag ttttatacat aatttaccat cagatagaac     5220

tttatggttc tagtacagat actctactac actcagcctc ttatgtgcca agtttttctt     5280

taagcaatga gaaattgctc atgttcttca tcttctcaaa tcatcagagg ccgaagaaaa     5340

acactttggc tgtgtctata acttgacaca gtcaatagaa tgaagaaaat tagagtagtt     5400

atgtgattat ttcagctctt gacctgtccc ctctggctgc ctctgagtct gaatctccca     5460

aagagagaaa ccaatttcta agaggactgg attgcagaag actcggggac aacatttgat     5520

ccaagatctt aaatgttata ttgataacca tgctcagcaa tgagctatta gattcatttt     5580

gggaaatctc cataatttca atttgtaaac tttgttaaga cctgtctaca ttgttatatg     5640

tgtgtgactt gagtaatgtt atcaacgttt ttgtaaatat ttactatgtt tttctattag     5700

ctaaattcca acaattttgt actttaataa aatgttctaa acattgcaac cca            5753


<210>  1927
<211>  2271
<212>  DNA
<213>  homo sapiens

<400>  1927
tgaggccagg agatggaggc tgcagtgagc tgtgatcaca ccactgtgct ccagcctgag       60

tgacagagca agaccctatc tcaaaaaaaa aaaaaaaaaa gaaaagctcc tgaggtgtag      120

acgccaactc tctctagctc gctagtgggt tgcaggaggt gcttacgcat gtttgtttct      180

ttgctgccgt cttccagttg ctttatctgt tcacttgtgc cctgactttc aactctgtct      240

ccttcctctt cctacagtac tcccctgccc tcaacaagat gttttgccaa ctggccaaga      300

cctgccctgt gcagctgtgg gttgattcca cacccccgcc cggcacccgc gtccgcgcca      360

tggccatcta caagcagtca cagcacatga cggaggttgt gaggcgctgc ccccaccatg      420

agcgctgctc agatagcgat ggtctggccc ctcctcagca tcttatccga gtggaaggaa      480

atttgcgtgt ggagtatttg gatgacagaa acacttttcg acatagtgtg gtggtgccct      540

atgagccgcc tgaggttggc tctgactgta ccaccatcca ctacaactac atgtgtaaca      600

gttcctgcat gggcggcatg aaccggaggc ccatcctcac catcatcaca ctggaagact      660

ccagtggtaa tctactggga cggaacagct ttgaggtgcg tgtttgtgcc tgtcctggga      720

gagaccggcg cacagaggaa gagaatctcc gcaagaaagg ggagcctcac cacgagctgc      780

ccccagggag cactaagcga gcactgccca acaacaccag ctcctctccc cagccaaaga      840

agaaaccact ggatggagaa tatttcaccc ttcagatccg tgggcgtgag cgcttcgaga      900

tgttccgaga gctgaatgag gccttggaac tcaaggatgc ccaggctggg aaggagccag      960

gggggagcag ggctcactcc agccacctga agtccaaaaa gggtcagtct acctcccgcc     1020

ataaaaaact catgttcaag acagaagggc ctgactcaga ctgacattct ccacttcttg     1080

ttccccactg acagcctccc acccccatct ctccctcccc tgccattttg ggttttgggt     1140

ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac ccaggacttc catttgcttt     1200

gtcccggggc tccactgaac aagttggcct gcactggtgt tttgttgtgg ggaggaggat     1260

ggggagtagg acataccagc ttagatttta aggtttttac tgtgagggat gtttgggaga     1320

tgtaagaaat gttcttgcag ttaagggtta gtttacaatc agccacattc taggtagggg     1380

cccacttcac cgtactaacc agggaagctg tccctcactg ttgaattttc tctaacttca     1440

aggcccatat ctgtgaaatg ctggcatttg cacctacctc acagagtgca ttgtgagggt     1500

taatgaaata atgtacatct ggccttgaaa ccacctttta ttacatgggg tctagaactt     1560

gacccccttg agggtgcttg ttccctctcc ctgttggtcg gtgggttggt agtttctaca     1620

gttgggcagc tggttaggta gagggagttg tcaagtctct gctggcccag ccaaaccctg     1680

tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa tctcacccca tcccacaccc     1740

tggaggattt catctcttgt atatgatgat ctggatccac caagacttgt tttatgctca     1800

gggtcaattt cttttttctt tttttttttt ttttttcttt ttctttgaga ctgggtctcg     1860

ctttgttgcc caggctggag tggagtggcg tgatcttggc ttactgcagc ctttgcctcc     1920

ccggctcgag cagtcctgcc tcagcctccg gagtagctgg gaccacaggt tcatgccacc     1980

atggccagcc aacttttgca tgttttgtag agatggggtc tcacagtgtt gcccaggctg     2040

gtctcaaact cctgggctca ggcgatccac ctgtctcagc ctcccagagt gctgggatta     2100

caattgtgag ccaccacgtc cagctggaag ggtcaacatc ttttacattc tgcaagcaca     2160

tctgcatttt caccccaccc ttcccctcct tctccctttt tatatcccat ttttatatcg     2220

atctcttatt ttacaataaa actttgctgc cacctgtgtg tctgaggggt g              2271


<210>  1928
<211>  1563
<212>  DNA
<213>  homo sapiens

<400>  1928
gctcagcatt tggggacgct ctcagctctc ggcgcacggc ccagcttcct tcaaaatgtc       60

tactgttcac gaaatcctgt gcaagctcag cttggagggt gatcactcta cacccccaag      120

tgcatatggg tctgtcaaag cctatactaa ctttgatgct gagcgggatg ctttgaacat      180

tgaaacagcc atcaagacca aaggtgtgga tgaggtcacc attgtcaaca ttttgaccaa      240

ccgcagcaat gcacagagac aggatattgc cttcgcctac cagagaagga ccaaaaagga      300

acttgcatca gcactgaagt cagccttatc tggccacctg gagacggtga ttttgggcct      360

attgaagaca cctgctcagt atgacgcttc tgagctaaaa gcttccatga aggggctggg      420

aaccgacgag gactctctca ttgagatcat ctgctccaga accaaccagg agctgcagga      480

aattaacaga gtctacaagg aaatgtacaa gactgatctg gagaaggaca ttatttcgga      540

cacatctggt gacttccgca agctgatggt tgccctggca aagggtagaa gagcagagga      600

tggctctgtc attgattatg aactgattga ccaagatgct cgggatctct atgacgctgg      660

agtgaagagg aaaggaactg atgttcccaa gtggatcagc atcatgaccg agcggagcgt      720

gccccacctc cagaaagtat ttgataggta caagagttac agcccttatg acatgttgga      780

aagcatcagg aaagaggtta aaggagacct ggaaaatgct ttcctgaacc tggttcagtg      840

cattcagaac aagcccctgt attttgctga tcggctgtat gactccatga agggcaaggg      900

gacgcgagat aaggtcctga tcagaatcat ggtctcccgc agtgaagtgg acatgttgaa      960

aattaggtct gaattcaaga gaaagtacgg caagtccctg tactattata tccagcaaga     1020

cactaagggc gactaccaga aagcgctgct gtacctgtgt ggtggagatg actgaagccc     1080

gacacggcct gagcgtccag aaatggtgct caccatgctt ccagctaaca ggtctagaaa     1140

accagcttgc gaataacagt ccccgtggcc atccctgtga gggtgacgtt agcattaccc     1200

ccaacctcat tttagttgcc taagcattgc ctggccttcc tgtctagtct ctcctgtaag     1260

ccaaagaaat gaacattcca aggagttgga agtgaagtct atgatgtgaa acactttgcc     1320

tcctgtgtac tgtgtcataa acagatgaat aaactgaatt tgtactttag aaacacgtac     1380

tttgtggccc tgctttcaac tgaattgttt gaaaattaaa cgtgcttggg gttcagctgg     1440

tgaggctgtc cctgtaggaa gaaagctctg ggactgagct gtacagtatg gttgccccta     1500

tccaagtgtc gctatttaag ttaaatttaa atgaaataaa ataaaataaa atcaaaaaaa     1560

aaa                                                                   1563


<210>  1929
<211>  1376
<212>  DNA
<213>  homo sapiens

<400>  1929
gcaggaccgt cattgacgcc atgagcgcgc tgctgcggct gctgcgcacg ggtgccccag       60

ccgctgcgtg cctgcggttg gggaccagtg cagggaccgg gtcgcgccgt gctatggccc      120

tgtaccacac tgaggagcgc ggccagccct gctcgcagaa ttaccgcctc ttctttaaga      180

atgtaactgg tcactacatt tccccctttc atgatattcc tctgaaggtg aactctaaag      240

agattctttc ttgtggagaa gttattcatg tgaagatcct tggaattttg gctcttattg      300

atgaaggtga aacagattgg aaattaattg ctatcaatgc gaatgatcct gaagcctcaa      360

agtttcatga tattgatgat gttaagaagt tcaaaccggg ttacctggaa gctactctta      420

attggtttag attatataag gtaccagatg gaaaaccaga aaaccagttt gcttttaatg      480

gagaattcaa aaacaaggct tttgctcttg aagttattaa atccactcat caatgttgga      540

aagcattgct tatgaagaag tgtaatggag gagctataaa ttgcacaaac gtgcagatat      600

ctgatagccc tttccgttgc actcaagagg aagcaagatc attagttgaa tcggtatcat      660

cttcaccaaa taaagaaagt aatgaagaag agcaagtgtg gcacttcctt ggcaagtgat      720

tgaaacatct gaaattctgc tgtcaagatt cccatctcta aggactccaa gtgctagaga      780

caagggggtc tatgagcatt tactgacttc ctgttaaaac ttcatttttt caaacttttt      840

gagctatgca atatataaat aaacagtaag aattttaaat tactctcctt tggacattta      900

ttgatataaa aagaagattt tggccaggca cggtggctca tgcctgtaat ttcagcactt      960

tgggaggccg aggtgggcag atcacaaggt caggagttca agaccagcct ggccagtatg     1020

ttgaaacccc atctctatta aaaatacaaa aattagccag gcgtggtggt gcatgcctgt     1080

agacccagct actcaggagg ctgaggcaga agaactgctt gagcccagga ggcagaggtt     1140

gcagtgagca gagattgtgc cactgcactc cagcctaggc gacagagaga gactccgtct     1200

caaaaaaaaa aaaaagattt tgtttcattt catagcacaa atttagaggc attgagttga     1260

ccatttctag tttctatacc tgaaggaacc cattgatttt accagttttt atttctgtag     1320

attggatgta aaaatcacag attcaataaa ttaataaact ttgtgtaaaa aaaaaa         1376


<210>  1930
<211>  8031
<212>  DNA
<213>  homo sapiens

<400>  1930
agggatccta cctcttttga ccggagatgt tgaaaagcac gaccaaagtt tttggcttgg       60

tctcttgctt tccacaacga gataaagtct gaagcctgta actctccctg tcccgcggga      120

gcgtgcaaag ggagggaaga taagcggcgt gggtgagggg tggcggcgca gaacccagga      180

agggagcaga ggcgagagcc agcctccggc aggagggcgt agaccccggt gccagccaga      240

acggctccag ccttcccgcg gccagagagc cagcggcggg aggggacggg cgggacctcc      300

gcggacagcc ccgggtgcgg accagcgggc agcggccggc gagaccctcc ctggatccgc      360

ccagagctta ccggaccctg cgcgcccccg tcccggctcc cggccggctc gggggagaag      420

gcgcccgagg ggaggcgccg gacagatcgc gtttcggagg cggcgcaggt gctgtaaact      480

gcaaaccata atcctgtctt aatactgcaa acaaatcata gtggaactaa ggggaactta      540

atttactgtt tccaggttaa ctaaggtctc agctgtaaac caaaagtgag aggagacatt      600

aagattttca ttcttaccgg gttgtcttct tcctgaagag caatggagcc gcttttactt      660

ggaagaggac taatcgtata tctaatgttc ctcctgttaa aattctcaaa agcaattgaa      720

ataccatctt cagttcaaca ggttccaaca atcataaaac agtcaaaagt ccaagttgcc      780

tttcccttcg atgagtattt tcaaattgaa tgtgaagcta aaggaaatcc agaaccaaca      840

ttttcgtgga ctaaggatgg caaccctttt tatttcactg accatcggat aattccatcg      900

aacaattcag gaacattcag gatcccaaac gaggggcaca tatctcactt tcaagggaaa      960

taccgctgct ttgcttcaaa taaactggga atcgctatgt cagaagaaat agaatttata     1020

gttccaagtg ttccaaaatt cccaaaagaa aaaattgacc ctcttgaagt ggaggaggga     1080

gatccaattg tcctcccatg caatcctccc aaaggcctcc cacctttaca catttattgg     1140

atgaatattg aattagaaca catcgaacaa gatgaaagag tatacatgag ccaaaaggga     1200

gatctatact tcgcaaacgt ggaagaaaag gacagtcgca atgactactg ttgctttgct     1260

gcatttccaa gattaaggac tattgtacag aaaatgccaa tgaaactaac agttaacagt     1320

ttaaagcatg ctaatgactc aagttcatcc acagaaattg gttccaaggc aaattccatc     1380

aagcaaagaa aacccaaact gctgttgcct cccactgaga gtggcagtga gtcttcaatt     1440

accatcctca aaggggaaat cttgctgctt gagtgttttg ctgaaggctt gccaactcca     1500

caggttgatt ggaacaaaat tggtggtgac ttaccaaagg ggagagaaac aaaagaaaat     1560

tatggcaaga ctttgaagat agagaatgtc tcctaccagg acaaaggaaa ttatcgctgc     1620

acagccagca atttcttggg aacagccact cacgattttc acgttatagt agaagagcct     1680

cctcgctgga caaagaagcc tcagagtgct gtgtatagca ccggaagcaa tggcatcttg     1740

ttatgtgagg ctgaaggaga acctcaaccc acaatcaagt ggagagtcaa tggctcccca     1800

gttgacaatc atccatttgc tggtgatgtt gtcttcccca gggaaatcag ttttaccaac     1860

cttcaaccaa atcatactgc tgtgtaccag tgtgaagcct caaatgtcca tggaactatc     1920

cttgccaatg ccaatattga tgttgtggat gtccgtccat tgatacaaac caaagatgga     1980

gaaaattacg ctacagtggt tgggtacagt gctttcttac attgcgagtt ctttgcttca     2040

cctgaggcag tcgtgtcctg gcagaaggtg gaagaagtga aacccctgga gggcaggcgg     2100

tatcatatct atgaaaatgg cacattgcag atcaacagaa ccaccgaaga agatgctggg     2160

tcttactcat gttgggtaga aaatgctata ggaaaaactg cagtcacagc caatttggat     2220

attagaaatg ctacaaaact tagagtttct cctaagaatc ctcgtatccc caaattgcat     2280

atgcttgaat tacattgtga aagcaaatgt gactcacatt tgaaacacag tttgaagttg     2340

tcctggagta aagatggaga agcctttgaa attaatggca cagaagatgg caggataatt     2400

attgatggag ctaatttgac catatctaat gtaactttag aggaccaagg tatttactgc     2460

tgttcagctc atactgctct agacagtgct gccgatataa ctcaagtaac tgttcttgat     2520

gttccggatc caccagaaaa ccttcacttg tctgaaagac agaacaggag tgttcggctg     2580

acctgggaag ctggagctga ccacaacagc aatattagcg agtatattgt tgaatttgaa     2640

ggaaacaaag aagagcctgg aaggtgggag gaactgacca gagtccaagg aaagaaaacc     2700

acagttatct tacctttggc tccatttgtg agataccagt tcagggtcat agccgtgaac     2760

gaagtaggga gaagtcagcc tagccagccg tcagaccatc atgaaacacc accagcagct     2820

ccagatagga atccacaaaa cataagggtt caagcctctc aacccaagga aatgattata     2880

aagtgggagc ctttgaaatc catggagcag aatggaccag gcctagagta cagagtgacc     2940

tggaagccac agggagcccc agtggagtgg gaagaagaaa cagtcacaaa ccacacattg     3000

cgggtgatga cgcctgctgt ctatgcccct tatgatgtca aggtccaggc tatcaatcaa     3060

ctaggatctg ggcctgaccc tcagtcagtg actctctatt ctggagaaga ctatcctgat     3120

acagctccag tgatccatgg ggtggacgtt ataaacagta cattagttaa agttacctgg     3180

tcaacagttc caaaggacag agtacatgga cgtctgaaag gctatcagat aaattggtgg     3240

aaaacaaaaa gtctgttgga tggaagaaca catcccaaag aagtgaacat tctaagattt     3300

tcaggacaaa gaaactctgg aatggttcct tccttagatg cctttagtga atttcattta     3360

acagtcttag cctataactc taaaggagct ggtcctgaaa gtgagcctta tatatttcaa     3420

acaccagaag gagtacctga acagccaact tttctaaagg tcatcaaagt tgataaagac     3480

actgccactt tatcttgggg actacctaag aaattaaatg gaaacttaac tggctatctt     3540

ttgcaatatc agataataaa tgacacctac gagattggag aattaaatga tattaacatt     3600

acaactccat caaagcccag ctggcacctc tcaaacctga atgcaactac caagtacaaa     3660

ttctacttga gggcttgcac ttcacagggc tgtggaaaac cgatcacgga ggaaagctcc     3720

accttaggag aagggagtaa aggtatcggg aagatatcag gagtaaatct tactcaaaag     3780

actcacccaa tagaggtatt tgagccggga gctgaacata tagttcgcct aatgactaag     3840

aattggggcg ataatgatag catttttcaa gatgtaattg agacaagagg gagagaatat     3900

gctggtttat atgatgacat ctccactcaa ggctggttta ttggactgat gtgtgcgatt     3960

gctcttctca cactactatt attaactgtt tgctttgtga agaggaatag aggtggaaag     4020

tactcagtta aagaaaagga agatttgcat ccagacccag aaattcagtc agtaaaagat     4080

gaaacctttg gtgaatacag tgacagtgat gaaaagcctc tcaaaggaag ccttcggtcc     4140

cttaataggg atatgcagcc tactgaaagt gctgacagct tagtcgaata cggagaggga     4200

gaccatggtc tcttcagtga agatggatca tttattggtg cctacgctgg atctaaggag     4260

aagggatctg ttgaaagcaa tggaagttct acagcaactt ttccccttcg ggcataaaca     4320

caacatatgt aagcaacgct actggttcac cccaaccttc catatttatc tgttcaaagg     4380

agcaagaact ttcatatagg aatagaaaca tgctggccga agatttcatc cagaagtcaa     4440

catcctgcaa ttatgttgaa aagagtagta ctttcttcaa aatataaaat gccaagcact     4500

tcaggcctat gttttgctta tattgttttc aggtgctcaa aatgcaaaac acaaaacaaa     4560

tcctgcattt agatacacct caactaaatc caaagtcccc attcagtata ttccatattt     4620

gcctgatttt actattcggt gtgtttgcat agatgttgct acttggtggg tttttctccg     4680

tatgcacatt ggtatacagt ctctgagaac tggcttggtg actttgcttc actacaggtt     4740

aaaagaccat aagcaaactg gttatttaaa atgtaaaaag gaatatgaaa gtcttattaa     4800

aacacttcat tgaaaatata cagtctaaat ttattattta aattttacta gcaaaagtct     4860

taggtgaaca atcaactagt atttgttgag ctcctatttg cccagagatg gtcatattta     4920

aacagaagta tacgtttttc agtttcaaca tgaatttttt tatttctgtc agttatgaca     4980

tccacaagca tcactttttg tgtctgtttt tttttttttt cttggactaa attcaactgc     5040

atggaagcgg tggtcagaag gttgttttat acgagaacag gcagaaagtg cccattgttc     5100

aggattctaa tagctacatc tacttaatat cttcatttct aaattgactg cttttacctt     5160

tttctcatgt ttatataatg gtatgcttgc atatatttca tgaatacatt gtacatatta     5220

tgttaatatt tacacaattt aaaatataga tgtgttttat tttgaagtga gaaaatgaac     5280

attaacaggc atgtttgtac agctagaata tattagtaag atactgtttt tcgtcattcc     5340

agagctacaa ctaataacac gaggttccaa agctgaagac tttgtataaa gtatttgggt     5400

tttgttcttg tattgctttc tttcaacagt ttcaaaataa aatatcatat aaatattgag     5460

ggaaatgttt tcatattttt caaaataggt ttttattgtt gaatgtacat ctaccccagc     5520

ccctcaaaag aaaaactgtt tacatagaaa ttcctacaca tacgtttgcg tatatgttat     5580

tttaaacatc tttgtggtga gaattttttc cccgatattc tccttctgtc aaagtcagaa     5640

caaattcagg gaatttattt tctggcagtt gtgctccagt ccttttaaaa ttgtacatga     5700

acatgtttta gaaacaatat ggaggatgat gcatacatgt cggtcaagtt cagcgctcga     5760

cattttatgg aaagattttt ttaaccttac cacgaaatac ttaactactg tttaagtgaa     5820

ttgacttatt tcactttagt ttttgaactg tgattattgg tatactgtta tatcctcaac     5880

ttggatttat ggtaacccct tatagttcat ggagaccaaa atttggggta tttataatag     5940

tcagcgcagg aatgcacatg gaatatctac ttgtcctttt gaacctcacg agtcatccag     6000

aatgtataga caggaaaagc atgtcttatt taaaactgta atttatgggc tcaggatctg     6060

accgcagtcc cgggagtaag catttcaaag ggggaaggca gtgtggtccc taccctgtgt     6120

gaatgtgagg atgtagacat ccatcagtgc aactcgagct ccatcctcct ccgatttcta     6180

aggttccagt tttctggagg gacagtcatc atgttttgat ttatctggga gaaaactgtg     6240

gtgcacagct tgtgaggagg gcaaggttgt gacgttcgag cttagttctg gtgttattct     6300

gtctcctctt ctttgtcatc agccaaaacg tggtttttaa agagagtcat gcaggttaga     6360

aataatgtca aaaatattta ggaatttaat aacctttaag tcagaaacta aaacaaatac     6420

tgaaatatta gctcttccta cacttcgtgt tcccctttag ctgcctgaaa atcaagattg     6480

ctcctgctca gatcttctga gtggctaaaa cttatggata tgaaaaatga gattgaatga     6540

tgactatgct ttgctatcat tgttaccttt cctcaatact atttggcaac tactgggact     6600

cttcagcaca aaaggaatag atctatgatt gaccctgatt ttaattgtga aattatatga     6660

ttcatatatt ttatgaatca gaataacctt caaataaaat aaatctaagt cggttaaaat     6720

ggatttcatg attttccctc agaaaatgag taacagagtc cacggcgtgc aatggtaatt     6780

ataaattggt gatgcttgtt tgcaaattgc ccactcgtga taagtcaaca gccaatattt     6840

aaaactttgt tcgttactgg ctttacccta actttctcta gtctactgtc aatatcattt     6900

taatgtaatt gattgtatat agtctcaaga atggttggtg ggcatgagtt cctagagaac     6960

tgtccaaggg ttgggaaaat ccaaattctc ttcctggttc cagcactgat tttgtacata     7020

aacattaggc aggttgctta acctttttat ttcaaactct ctcaactcta aagtgctaat     7080

aataatctca gttaccttat ctttgtcaca gggtgttctt ttttatgaag aaaaatttga     7140

aaatgataaa agctaagatg ccttctaact tcataagcaa acctttaact aattatgtat     7200

ctgaaagtca cccccacata ccaactcaac ttttttcctg tgaacacata aatatatttt     7260

tatagaaaaa caaatctaca taaaataaat ctactgttta gtgagcagta tgatttgtac     7320

atgccattga aaattattaa tcagaagaaa attaagcagg gtctttgcta tacaaaagtg     7380

ttttccacta attttgcatg cgtatttata agaaaaatgt gaatttggtg gttttattct     7440

atcggtataa aggcattgat attttagatg cacccgtgtt tgtaaaaatg tagagcacaa     7500

tggaattatg ctggaagtct caaataatat ttttttccta ttttatactc atggaagaga     7560

taagctaaag aggggacaat aatgagaaat gttggtgtgc ttttctaagc atttaaaaca     7620

taattgccaa ttgaaaccct aaatatgttt acataccatt aagatatgat tcatgtaaca     7680

atgttaaatt aattataatg ggattgggtt tgttatctgt ggtagtatat atcctagtgt     7740

tcctatagtg aaataagtag ggttcagcca aagctttctt tgttttgtac cttaaattgt     7800

tcgattacgt catcaaaaga gatgaaaggt atgtagaaca ggttcacgtg attacctttt     7860

tcttttggct tggattaata ttcatagtag aactttataa aacgtgtttg tattgtaggt     7920

ggtgtttgta ttatgcttat gactatgtat ggtttgaaaa tattttcatt atacatgaaa     7980

ttcaactttc caaataaaag ttctacttca tgtaatccaa aaaaaaaaaa a              8031


<210>  1931
<211>  3015
<212>  DNA
<213>  homo sapiens

<400>  1931
gtgtgtttga gtgtgaaatg tgctaataag gaggagagac ctctcctttg caatgtgctg       60

cggcaggaga aagcaggctg ccggcccctg cctccctgaa tcctcagtgg ctgactggat      120

accgcttctg ggggttgctg tgcacatgaa tgtttgctat tgttccaggc gcacgtcggc      180

cttaagaaat agcacaaaac aggcccatcc ttattcagaa gccgggcccc ctccatcact      240

caaactgggc ctttcaggtc acatgccgga ggctgctgca gacaggaccc agctgcctca      300

aatctgccgc ctaacataag ctgcggttcg aaaatcctga cagcacaggg cttcctgggc      360

tctgcagagc aaactggaaa gagctgggat ccaggcacta tgttctctga agaactgtgg      420

ctggaaaatg agaaaaagtg tgctgtggtt cggaagtcta agcagggcag gaaacgccaa      480

gaactgctgg ccgtagcctt cggggtgaag gtgggtgtca aaggcggctt tctttggccc      540

cctctcaaac tctttgcctg ttcacagatc tcctccctgg ttcgaagggc tgccctcaca      600

cacaacgaca accacttcaa ttatgagaag acacacaact ttaaggtcca cacgttccga      660

ggcccacact ggtgtgaata ttgtgccaat ttcatgtggg ggctcatcgc ccaaggggtc      720

cggtgctcag actgtggatt gaacgtacac aaacagtgtt ccaagcacgt tcccaatgac      780

tgccaacctg atctcaagag gatcaagaaa gtgtactgtt gtgacctcac aacacttgtg      840

aaggctcaca acactcagag acccatggtg gtagacatat gcattcggga aattgaagca      900

agaggattaa aatcggaagg cctttacaga gtctctgggt tcactgaaca cattgaagat      960

gtcaaaatgg catttgacag agatggtgaa aaggccgata tatctgccaa tgtctatcca     1020

gacataaaca tcatcactgg agcccttaaa ctgtatttca gagacttacc catccctgtc     1080

atcacatatg atacctattc caaatttata gatgcagcaa aaatctccaa tgcagatgag     1140

aggctggaag ccgtccatga agtgctgatg ctgctgcctc ctgcccacta tgaaaccctc     1200

cggtacctaa tgatccacct caaaaaggtt actatgaatg aaaaagacaa tttcatgaat     1260

gcagaaaatc tggggatcgt gtttgggccc actctgatga ggccccctga ggacagcacc     1320

ctgaccaccc tgcatgatat gcggtaccaa aagctgattg tgcagatttt aatagaaaac     1380

gaagacgttt tattctaatc catcagggaa atgagctgaa tggccccagc accatccaag     1440

ttgacacagc taaaggaata aaaacatttc ttaccacttg atttgttttc caagcaagtg     1500

ctagaatttg ctggactgca gaggatcgct gagtggggta ctgtgtctca tagacatgcg     1560

ccacctccac gtgagaacaa gggtgaaggt gagggaagcc cctcaccttg ggtcttttgc     1620

tgtgcctcct atgtatgtct ggtttgctgg aagagtgatt aatacatctt taatttatta     1680

aaaaacaatg tagaccttta aacttcagtc ttattggtaa taaaagggaa cttaattcat     1740

acaggtactt gatacagtta tacattttcc acttacaaaa agaagacaat tctgttaaat     1800

gaaacgtgta tcgtaaaatg tatttttatt ttacccacga gaatgttgtt atttttagca     1860

aatagaactc aatgcagtgc attggttatt accctgtgta ccttgtccct cattttgctg     1920

tgacaccctg aaaaagctga ccacaaatgc agtattatct tgacatacct ctgtcctcct     1980

cagtgctttt taatgaaatt tcacctgccc cttgtgttcc tgctttggat agtttttgct     2040

cttaagcatt ggcattcttc tattgtatgg tatgtattta tagcaattgt aggatggtct     2100

gaaatgtcca cacactttct atgcatacaa attttgtgaa ttcccaaagt atgctttgga     2160

attggtcata gtcttttcgt atcatgagtg tgtatcccag aagatacaga atgcggtcat     2220

tttacctgaa attatttgag aacactggat gtatctggtc tgtgtaaaaa gttagcactt     2280

accctctttt cttcctggcc aagccctctg aattcatctg ttaatatcaa attgtatttt     2340

tgccacattt ctgtattggt gaaaagcgaa tctgcagaat aactgtcaac gtttttcatt     2400

cttgttttac aaacctattt tttaaagtga gaataaggtt ggtttttacc aaatatttgt     2460

tcctccttga caaaagtagc tctgtgtgga taatatgatt ttattactac agttccagtc     2520

acttggttat atttatctta gcatgagcct ttcacaccaa gatttctata ttttgtaaca     2580

taggtgaaat atttaaaaca tcaaaaactg taaatctaga tttttaaaaa atccaactgc     2640

aatgtctttt cctttgattg agatgatttg tgtaaactca ccagtcttgc tttggagtga     2700

gcagaagaga atgactattt tacgtggagc atcattgtgt gactgttgac ctggacagtc     2760

ccaagggcta tgcagatgga ctccattggc acagggaggt ttgacctctt ccctgctatt     2820

atccctcctc ccaactgtac agatttgttt gttgtagttt atgtacttct tgatactgtc     2880

aaaaaattat ctggaaatgg ttttattttg tgaagtgaac aatactttgt aatttatgat     2940

agtgtaaatg gaaggcaaag catcacatgt attaaattct tctgtctatt attctggaaa     3000

aaaaaaaaaa aaaaa                                                      3015


<210>  1932
<211>  7233
<212>  DNA
<213>  homo sapiens

<400>  1932
cgtgggctgc tgcggagccg gcagcgcagg cgggcggagc ggagctgccc ccgtggtggc       60

gggcgatgcc cccgtgagcc tccctcgccg cccctccccg ccccgcgtgc ctatccactc      120

ggagtccgcg ccagcctggg gccgggccgc gcctactgcc gggttcgcgg ggcggggtcc      180

cggggcagca cctgccccgc cttgcggagc cgcctcggcc tgtggaggcc ccctccctgt      240

ctggaccccg gccccacctc cggacccttt tatcacatcg cctcctctgg gagcctgccc      300

tgattgcctt cacctcattt cttgaaaatt ggtgttttgg cagaagtcaa ttgaagcctt      360

gtgcaaatgc cctaggggtg tgctgttggg aggcagcccc ctgtgatgcg gaacaccagg      420

ctcagattca tcagttcgag ctgcctgagg ccctgccacc ccggggacca tgtttaacgg      480

ggagccaggt cctgcctcat ctggggcctc caggaatgtg gtgcggagct ccagcattag      540

cggtgaaatc tgcggatccc agcaagccgg gggcggggct gggaccacca ccgccaagaa      600

gcggcggagc agcctgggtg ccaagatggt ggccatcgtg ggcctgactc agtggagcaa      660

gagcacactc cagcttccgc agcctgaagg ggccaccaag aagctgcgca gcaacatccg      720

ccggagcacg gagacaggca tcgcggtgga gatgcggagc cgggtcacac gccagggcag      780

ccgggagtcc accgatggga gcaccaacag caacagctcc gacggcacgt tcatcttccc      840

cactacccgg ctaggggctg aaagccagtt cagcgatttc ctggatgggc tgggaccagc      900

tcagattgtg gggcgacaga cactggcaac accacccatg ggagatgtgc acattgccat      960

catggaccgg agtggccagc tggaggtgga agtgattgaa gctcggggcc tgacccccaa     1020

accaggctcc aaatccctcc cagccaccta tatcaaggtt tacctgctgg agaatggggc     1080

ctgcttggcc aagaagaaga caaagatgac caagaagacc tgtgatcccc tgtaccagca     1140

ggctctgctc tttgacgagg gaccccaggg caaggtgctg caggtgatcg tctggggaga     1200

ctatggccgc atggaccaca agtgcttcat gggcatggcc cagatcatgc tggacgagct     1260

ggacctcagc gccgcggtca ccggctggta caaactcttc cccacctcct cagtggcaga     1320

ctccacactc ggatccctca ccaggcgcct gtcccagtct tccctggaga gtgccaccag     1380

cccctcatgc tcttaaggat gtcaggaaga ggccaggatg gtggtgtggg gaggggtgcc     1440

tgctggcccc atgtcctccc ctgtacatag tcttcgtgtc tttctggacc ccttgtcctg     1500

ctgcatgcct gttggctact gggctcatcc cagctggcag tggagactgt agtgtgtgcg     1560

tgtgtgcgtg cgtgtgtgtg tgtgtgtacg tgaccacgtt ctatctgttc atttgtctgg     1620

gtatagtcac tcctggtgat gatatgggct gaaatgtctc cacgtctctt tgtgtcttgt     1680

tgaaaagaaa cccaaaggag tgttgtgtgg acatgactca ccctgaggag tctccaggga     1740

tggaggtggg gcatgcggcc actggtcggt gctgcctggt cctggcctgg ggcagagcct     1800

gtgtgttctt cacctgtgcc tgctcctggt ggtctctgct ttgttttctg tcttgtcttt     1860

tgttccactc ttgactctcc cggctctgcc actgttttct gagaaatgta gcatccgctg     1920

cagctggcca cactgagggc cctctgggaa ccccacccca ctggagccgc tccggcagct     1980

cttcctgcca ctgaatgcgt tctgcagcat gtagcatgcc cacctagctc cctggccagg     2040

gccctgggga ggcagagggt acccagggga ctgagggctt agaaatgact ttctctatga     2100

ggctggaacc tcctccttct tccagtgaag cacgaggtct tggttccagg gttcctggcc     2160

aggtgccccc ttagcatttg ttcttcatct cctgtctctt caagcctccc cactccaccg     2220

tgccgaagga gctctgccag tgggcctggg caggcagcca cagagggcat gttatctgct     2280

aaagcaaaca gtcctcctga ggccctgagg gtggccctga ccccctcagg gctcattcct     2340

ggtgggcatg actcggtaag gaggttctgt gggtagggct gtttgctgga ataaggaggg     2400

ctgaggctga gttgttcccc gccactgttg aggatcccat ctgacatttg gggattcact     2460

gcatgaagtt gttcatttgg ggctccagtt tttgtgcatt tccagaccag ggtccctgtc     2520

tgggagctca gacttagctg ggctccagca gcctggctcc ggactctcgt ctgccaccat     2580

caccagctct gtctaagcaa tacttacccc tccgggcttc cctgctttcc tgtgccccac     2640

tgctgccctc tgcagagcca tctgctccag gcacccacct gcctctgctt gctttctcac     2700

ccatgtctgg ttggagcttc tcacagccac tcaaaccctg acttgatttg acaactgggc     2760

cctgttggtg gagaccagtg cctgaactgg accctgtgaa atctgtcccg tgggaatcct     2820

gaagtctgac tcaggaatgc ccagacctgt ccctgtccct cctcagctct agggtgaaag     2880

gcgagaggtt gcacaggaca tggacagagc agcccttggg tttgtatctg gtaggggaga     2940

aagcagcagg acagtggagg tgtgtggaag gcactctttc cacctctctc caggcattat     3000

ccccaggtgc tgaaatggct gtggccccag cacctgaggc aggggtacgc tacctggggt     3060

agcagtagaa aggtcttggg gtctgaatga cttggggcct ccattcataa ccaaagttgt     3120

aggggcatgg aggcagtggc gccttatgga taggtcatct cagcccaaag ggcctccttg     3180

gctggcatgg ttctgtgtta cgttgaagcc agagtcttat aacacctccc aagaaagata     3240

ggggaagaag ccagaacccc acctggcctg cccacaggac aagaagtggg taagggcagg     3300

aaggaaatga acggagttag ctcccaggct cctatctctg cctgagcctc tattcttata     3360

ttatcagaga aagggaccat tgggtgcata gagatgggga ggaggccact gggctgaatt     3420

ttctctttag gcggaaatgc tctccccagg cccattgcgt tcgtcaagtt cttggaaatg     3480

gacaaagggc tctgtcctcc tcgaccctag tgggggatca agaaggaaac tccgttgcaa     3540

aagggtattt taatctcctg tttatgatat attcacctct agagcagtca ctgtcagggt     3600

gttgcgaaaa tactctacac ctttgggatg atagggttgt tagtgaccca caggacagta     3660

tagatgtttg tggatgtagc actgagtggt gatacccaga ccagcagtca ccccaggaag     3720

tgggggctac ccataccctc attcctctgg tggggagctg cctgcagaga ggcctgccac     3780

tgggggttcc aggccgtggt gacccttgcc tctggggaag ggttagcaca ggggaggttc     3840

tagctggagg aggggtctga tgtgctggta acttgggctg acctacctac agtccctggc     3900

tgccaaaact gctcagcagt tgggccactc cactattcca cctctctaaa agaaggtaat     3960

ttcctcccca aattgacctt ggggaattat tcttttaacc ctttgcacca aataagttac     4020

tcatccccac ctggatttta ccccatgagg gtaaagttgt gtgaggctga cacgtctgtg     4080

tgatgcagtg tggctgcact taagggtctg tttctcagca tcatggatgc aggggcttgt     4140

ctgaaaagcc actctggacc tagcctgtcc cagaagagga gaatgcacaa gtgtaactcc     4200

tggttgtttg ctggggtggg ggagcatctg ctgtttgagg acggggggtg gggaaggaag     4260

gaacatgatc cctccagaag tctcccaccc tggggccaac tcactgccat gttcagtgtc     4320

ccggctccaa atgccccctt gcccagatga aaccctgcag tggttacagg aatggagctc     4380

tttgtcattc cacctcctct ggtcaggcga ggttcactgt gcatatggca gagacaggag     4440

tggccctgca gtgatgttgg gttgtgggca gggacagtga tggatgactc agagcgtctg     4500

tctttgtatt tctgctctgt tcattctgtc ccactttctt catagactcc ttttccctgc     4560

aatgggtttt tggtatgaaa aaggctccag taaatggagc caagtcttgg tttgacaagg     4620

ggaacttgat ccttcaggga agaatcatct ccaaaatgac tccccatctg gtttcttcta     4680

ccacccaatt ctactaggaa aggagcactt aggaggctct tgggatgcag caagtcccag     4740

gcaatgccag catttcatgg gggctgaggc agaacccagg agctccaaga aaggccaccc     4800

atagagctca tcctctgtgg aatcactgcc ggttagaaca ctgaggtcaa gccagtcctc     4860

ccatggtcat gccacccacc agggaagcat gcctgatctc ttctttactg ccagccttga     4920

ggagagcaga agcctccatt tttaaagaca ataaagacct ccaagggtac ttctttggaa     4980

atgaaatgta gcacaatctt agcctacgtt accaggagcc ctgacatgca accagggtcc     5040

ctcttccatg ccctgctgcc caggagttgc tgagctcctc ttcccctggg gttccagccc     5100

tcctaatacc tcatattccc catcttcctc agcccagaaa gcaatggggc tttagtgatg     5160

ctcctctttt gtgtctctct ggttgcctct agcactgtgc aaactctgca agaaattgct     5220

gcctttgctt gatgttgtag atgagttgcc ctccacctgg ctggagagat ggcacatcat     5280

tcagggccag aaggttgtcc agcagtgttt ctgcagtggc tgcagggaga tggaaaagaa     5340

gagccctgct tccctgcctc ctcctacctt tctcttccac tcctcagagt tttcttctcc     5400

agtatcctga catgtaaaga gattctttaa aatgctgctt cttctactgg actgtctttc     5460

actgagtagt cagggaggag atgaaaatgt ggacacatcc ccccgccttc tccctcaacc     5520

ttttcactca cgtcagaaga ggttggggca aaacaaaaca agcatgattg aagagcaggg     5580

gaagcccaca caatcaggtg agccctgatg ggggctggac tggcctggtc tggctgggaa     5640

aggattcttt taaaagcgtg cctgagcatc tcagagcaat gtcagtgatg ccaaagagag     5700

caacttggcc tccttgggca ccaactctga tggctgagtt gcacaaacgt ggctcagatg     5760

ttggcatgcc cgatggtggg accttgttct ctgataaagg gcttaatctt tccatgtagc     5820

aaagcaactt tccctccctc ccctcccccc gaaccctgag cttgggcttg tgtgggccca     5880

gcatggctgt gcctgtgagg gaagccacat cagtgagaga aagttgcatt ctctcagggg     5940

cctagattgg cttggggcag gtgcttgttg aaaagcatga gtgtttctgc tttgggaaac     6000

ccttccaggg ctctggttgg aaacttggcc agtaaggaca gggccttggg cctcccaagg     6060

agttcacaat gatgccagga agggtccctg agcctgggtt ccagtcagct tggctaacag     6120

aatggggctt gggaattcca ggggcaactg agcatccacc ccattagcca gtgatctgga     6180

cagggacagc tggctacagg gaatcaaagg ctgttctgta cagttttacc agaaactgtg     6240

accttgggta aggctcctca cttttctggg cctcaacttc ctcatctgca aaatcagagc     6300

attagctgct ctccccatga ttccctccca gttttaatta aaagtctctg atctggagca     6360

catgagggtt gcgagcctgg tgcacctggt tcctgtctcc gtgggctggt ttccttcagc     6420

ccctgatgcc caggctgggt gcaggctctc atctggtcca tgcccagatg ctgcctcaga     6480

caagaactct gggaatccta acagactctg ctttcctctc ttcgtggttt gtcctccctc     6540

ttttattctt gtgtaatgat gagacataat taagggtcat ctacaatgga caattttcaa     6600

ggtgctgatg tgatgtcaca acctccgcta catcctgagt aagtcagtgt ccccaacagc     6660

agatgaggct gggtctttcc tcatttctgc ttctgggatg acatcagtgg gagagttgaa     6720

gatctgagaa ttctaaagga aatgttctct gatgggagga gagagggaac ttatttccct     6780

tcaaagtagt ttgcttctta agaccactcc tccctccaga atgtctttaa ccagacatca     6840

tttcagaagg tggggcagct gcttccttag gaagagtggg cctgatagct caaccaactc     6900

ctttagcatg taaactcaca gaaggcaaga accccttttt ttagactttc caaatgcatc     6960

ctgcaaagag agagatagct gatagggact gacaagcaca ctgtttagat aagaagcaat     7020

tagcctttta tatctgtgct ctatacattt tctatgtgca gcatctttcc taacttgttg     7080

tggttcccgg gtggcaggtg cacagctggg agggactgcc ggctgtttcg tacaacattc     7140

ttgccaattc ccttgaggag aaaattcttc acatggcttc tgcatgtaca gtatttgggc     7200

agcaaaacat gattaaagtc agtttgaaaa tgg                                  7233


<210>  1933
<211>  1459
<212>  DNA
<213>  homo sapiens

<400>  1933
aaggcgattg tcatatgata gctaagaagt ggcacattaa tgaagcgccg ctacaggggt       60

cttttctgct cctgtcaccg cttaaaacta tcagatggtt cgagggagga catggaggca      120

gccacctagc tcagcggaga cgcggagccc acagcagcgc cctccggagc cctaacacgt      180

cgctgccacc atccgcgccg ggactccgca gccgagctcg gccgcccgca ggacgctcca      240

ggagcgtcgc ggaccgggcg gcacgggacg ctgcggggct gagctcaaga gcccaggttc      300

gcgccgagtc caaccggacc cggacgctgc gcgcggagtg cgcgtcgagt gcgcgccgag      360

agagaagcgg cgcgcagcgg cgtcctcccg gatgcggacg cgcaacttga agcaacttta      420

agatccgagc agtccgccgg cccgcgcgga cccagagcaa gaagagggcg aggaagaaga      480

tgcctcggcc cggccgcaac acgtacagcg accagaagcc gccctactcg tacatctcgc      540

tgaccgctat ggccatccag agctctcccg agaagatgct gccgctgagc gagatctaca      600

agttcatcat ggaccgcttc ccctactaca gggagaacac gcagcgctgg cagaacagtc      660

tgcgccacaa cctctccttc aacgactgct tcatcaagat cccgcggcgg ccggaccagc      720

caggcaaggg cagcttctgg gcgctgcacc caagctgcgg ggacatgttc gagaacggca      780

gcttcctgcg gcgccgcaag cgcttcaagg tgcttaagtc cgaccacctg gcgcccagca      840

agccagccga cgcggcgcag tacctgcagc agcaggccaa gctgcggctc agcgcgctgg      900

cggcctcggg cacgcacctg ccacagatgc ccgccgccgc ctacaacttg ggcggcgtgg      960

cgcagccctc gggcttcaag caccccttcg ccatcgagaa catcatcgcg cgggaataca     1020

agatgcctgg ggggctggcc ttctccgcca tgcagccggt gcccgctgcc tacccgctcc     1080

ccaaccagtt gactaccatg ggcagctcgc tgggcaccgg ctggccacac gtgtatggct     1140

ccgccggcat gatcgactcg gccaccccca tctccatggc gagtggcgac tacagcgcct     1200

acggcgtgcc gttgaagccg ctgtgccacg cggcgggcca aacgctgccc gccatccccg     1260

tgcccattaa gcccacgccg gccgccgtgc ccgcgctgcc tgcgctgcca gcgcccatcc     1320

ccaccttgct ctcgaactcg ccgccctcgc tcagccccac gtcctcgcaa acagccacca     1380

gccaaagcag ccccgccacc cccagcgaaa cgctcaccag cccggcctcc gccttgcact     1440

cggtggcggt gcactgacc                                                  1459


<210>  1934
<211>  1459
<212>  DNA
<213>  homo sapiens

<400>  1934
aaggcgattg tcatatgata gctaagaagt ggcacattaa tgaagcgccg ctacaggggt       60

cttttctgct cctgtcaccg cttaaaacta tcagatggtt cgagggagga catggaggca      120

gccacctagc tcagcggaga cgcggagccc acagcagcgc cctccggagc cctaacacgt      180

cgctgccacc atccgcgccg ggactccgca gccgagctcg gccgcccgca ggacgctcca      240

ggagcgtcgc ggaccgggcg gcacgggacg ctgcggggct gagctcaaga gcccaggttc      300

gcgccgagtc caaccggacc cggacgctgc gcgcggagtg cgcgtcgagt gcgcgccgag      360

agagaagcgg cgcgcagcgg cgtcctcccg gatgcggacg cgcaacttga agcaacttta      420

agatccgagc agtccgccgg cccgcgcgga cccagagcaa gaagagggcg aggaagaaga      480

tgcctcggcc cggccgcaac acgtacagcg accagaagcc gccctactcg tacatctcgc      540

tgaccgctat ggccatccag agctctcccg agaagatgct gccgctgagc gagatctaca      600

agttcatcat ggaccgcttc ccctactaca gggagaacac gcagcgctgg cagaacagtc      660

tgcgccacaa cctctccttc aacgactgct tcatcaagat cccgcggcgg ccggaccagc      720

caggcaaggg cagcttctgg gcgctgcacc caagctgcgg ggacatgttc gagaacggca      780

gcttcctgcg gcgccgcaag cgcttcaagg tgcttaagtc cgaccacctg gcgcccagca      840

agccagccga cgcggcgcag tacctgcagc agcaggccaa gctgcggctc agcgcgctgg      900

cggcctcggg cacgcacctg ccacagatgc ccgccgccgc ctacaacttg ggcggcgtgg      960

cgcagccctc gggcttcaag caccccttcg ccatcgagaa catcatcgcg cgggaataca     1020

agatgcctgg ggggctggcc ttctccgcca tgcagccggt gcccgctgcc tacccgctcc     1080

ccaaccagtt gactaccatg ggcagctcgc tgggcaccgg ctggccacac gtgtatggct     1140

ccgccggcat gatcgactcg gccaccccca tctccatggc gagtggcgac tacagcgcct     1200

acggcgtgcc gttgaagccg ctgtgccacg cggcgggcca aacgctgccc gccatccccg     1260

tgcccattaa gcccacgccg gccgccgtgc ccgcgctgcc tgcgctgcca gcgcccatcc     1320

ccaccttgct ctcgaactcg ccgccctcgc tcagccccac gtcctcgcaa acagccacca     1380

gccaaagcag ccccgccacc cccagcgaaa cgctcaccag cccggcctcc gccttgcact     1440

cggtggcggt gcactgacc                                                  1459


<210>  1935
<211>  7029
<212>  DNA
<213>  homo sapiens

<400>  1935
agcgcaggtc ccgacagagg tcgccgggtg gtggcgtcag ctgcggcgcc ctccgcgtgg       60

aaattagccg gttgcccggg caaatcaggg aggaagggag ggagctgaac acggaagtgg      120

tggcggcgcc cagggaaccg gcggaggcga tgaccgtgac ggctgggttg ggaccggaac      180

gccgaagcgg ggttgggggt ggcagaaaag catctgcttt gtaagaccta cacgaggtgc      240

aggagtggtt gggcctcccc tctccactta agcaagcgcc cagactgatg gcgatggtga      300

tggcagcagt tactcgcaca accccagtta agctgcgctc cgggaggagt tcatctgttg      360

tctgctctcc agtgacttcc gtttgtggag cctaagtgtt tctacagaat ccaactcaaa      420

tatcaaggac tatgatcaga atgctttcaa ggagtttttg ggcacatgat ggcagataca      480

tccagaaagt gcccagaaga aacttcctgc tggaaaaaat gaaaaagcag tatttataac      540

attagaatct ggataatttg ttaacatggc agaaaataat gaaaatatta gtaaaaatgt      600

agatgtaagg cccaaaacta gtcggagcag aagtgccgac agaaaagacg gttatgtgtg      660

gagtggaaag aagttatctt ggtcaaaaaa gagtgagagt tattcagatg ctgagacagt      720

gaatggtata gagaaaaccg aagtgtcttt aaggaaccaa gaaaggaagc acagctgttc      780

atccattgag ttggacttag atcattcctg tgggcatcga tttttaggcc gatctcttaa      840

acagaaactg caagatgccg tggggcagtg ttttccaata aagaattgta gtagtcggca      900

ctcttcaggg cttccgtcta aaaggaaaat tcatatcagt gaactcatgt tagataagtg      960

tcctttccca cctcgatcag atttagcctt taggtggcat tttattaaac gacacactgc     1020

tcctataaat tccaaatcag atgaatgggt aagcacagac ttgtctcaga ctgaattgag     1080

ggatggtcag ctaaaacgaa gaaatatgga agaaaatata aactgtttct cacataccaa     1140

tgttcagccc tgtgtcataa ccaccgacaa tgctttgtgt agagaaggtc ctatgactgg     1200

ctctgtgatg aacctggttt caaataacag tatagaagat agtgatatgg attccgatga     1260

tgaaattcta acactttgca caagttccag aaaaagaaac aaacccaaat gggatttgga     1320

tgatgaaatc ctgcagttgg aaacacctcc taaataccac acgcagattg attatgtcca     1380

ctgtcttgta ccagacctcc ttcagatcaa taacaaccca tgttactggg gagtgatgga     1440

taaatacgca gccgaagcac tactggaagg aaaaccagag ggtacctttt tacttcgaga     1500

ctcagcacag gaagactatt tattctctgt tagttttaga cgctatagtc gttctcttca     1560

tgctagaatt gaacagtgga atcacaactt tagctttgat gcacatgacc cctgtgtctt     1620

ccattctcct gacattactg ggctcctaga acattataag gacccaagcg cctgtatgtt     1680

ctttgaacca cttctatcca ctcccttaat tcggactttc cctttttccc tgcagcatat     1740

atgcagaaca gttatttgta actgtacaac ttatgatggc atcgatgccc ttccaattcc     1800

ttcttctatg aaattatatc tgaaggaata tcattataaa tcaaaagtta gagtactcag     1860

gattgatgca ccagaacagc aatgctagta acaggatggg aacatgggaa tgataatata     1920

tattttttct tttaatattt tatttttctt tttatgccac tttggatttt tctacaaagg     1980

cagtggtgtc caaaataaaa tctctgccct aaattttact aataaatcca tttttctagt     2040

gatacacaaa ttgtttaagg ttatacactc gagcttaaat agatattttt aaccaggtgt     2100

ttggtttttg tttttaccgt gtaggttgta tacttacatt ttttctttcc ttaatttata     2160

catgatcctt tttccttaat ttatacatga tccaggcaca tttgaaattt ggtaggcatt     2220

gcaaacacat ttgaatattg tgtatttcat actattcttt aaaagtaatc ttatgtcctt     2280

tcctacatgt aaaatatttt gttaatctat gccattagta gtattatata taaaatatag     2340

ttccccgtcc cccttttcat tgagtttgat attcttcagt aaagctgaat gttgtaattc     2400

accattcata ctaatgttat tgacttttgt aacttactaa tagggatgtt aaaagtaaca     2460

aaaccaagtc aaacttggtg tatttttatt ttaaatatta actctaaagc aggattacta     2520

aatttgatta atctggtcaa tgagaatcaa atggaaacat atcattctgg aggtgcactt     2580

actcttctac aatgtggccg gatcatttgt cattcctgaa taggtctttc tctcaacctg     2640

caagagctaa accatcttca aaacataaat cttgttcctt tctcattgga agctttgaaa     2700

ataatgataa cactattagt agctagtagt tactaaagtg ctaaagtaat tgtggggttt     2760

ttctgtatta gcttatgaac tgttgcttct acttagccct tttatagaaa ctctgagctg     2820

ttactttggg gaaattccac aatgtattag cagccacaaa tttccactgg taaccaaaga     2880

gtacctaagt agtttttcat tattttaagt tgaatttgaa taaagattcc agaaataaac     2940

atggagctca gtattcagga agcttaatac tgtttttgat ctacaagatc caaataatta     3000

tccctatctt cagaattaac ttagtctgta atgtggcttc aaaaaaagaa agccttttga     3060

cagctacatg acttacacca tacagaacag tactggacaa aaggggtgat attttaaatt     3120

tactatccca gaaacagggc aacgttttta gaaacatctt tagcccaaag taactagtaa     3180

aaataaatgg agtggtatcc tatcttcttt ttttaaggaa tcaatgaata ataaatgtag     3240

atagacaatt ttcttctggt gagctgtcta accctttgta cacattgaca tttttaatat     3300

cgtaactgat ttcttgatgc tagtttagct atattaggaa actgcttcta cctagattga     3360

aagaaatttg actcataaac ttccaagtta gaacaaatat ttcttcatta ttgttgcttt     3420

tatgtgagta gcatttccct atcttgcagt tctgttaaca tgaaaatggc atttttccat     3480

aatagcttta aaataatttt ttagtaatta ttacaaaatt aaggaaaatc tctattaccg     3540

ttatctttta gcattttttt tttcctcagt gatctcaaga ttgtcttagt ctcaatgaga     3600

tgtagctaca aaaatggcac ctcttagcag tgatgaggct caggatatcg gatatcataa     3660

caccaatgtc aggataaata tctcttctaa agacgatatt taccttttac aaggttagaa     3720

aagtctcata ctacctcatc tttattgtgg cgcttttgta gatcactgag aagcttatct     3780

tattaaccaa tataccactt cctaaatatc catctttggt gaaagaaaat agtgtggtaa     3840

gagtacccat gattatagtt ttttatcaga atttgataag attttctgtt tctgtgaaac     3900

aattatttta aatatttttc ttttaaaaat aactttttat cagtacagaa aaacctaagg     3960

gatgactagc ttacaaatat tctgttaagg ggtagtttta taaagaaaaa tgatatatag     4020

ttatgttgtc ttttatagtg ttaaaattag tatttatatg aaagtcaaga tctaagtacc     4080

ttttcatata attcaaactg attgcttgtg atatgttttc tctggctttt ttattttttc     4140

aacttcaagg tattaacagc tgttaacact taaaaagtac tgccacatat gtagccttga     4200

agtagttgat ctaataaatg agagcaggga ggagattcat tgactctgaa atgattttta     4260

tttttccttt ggtatttgct acagtgaaaa gaagtttgga aagtagatac ataaagactt     4320

gagaagggaa ttgtttaagg gaaaagaaaa gagtaataat tttttttaaa acattaagga     4380

attggaattc agaaaggtta cccccttcct ctgtgtcttt gtaaggatac atttggaaga     4440

acatacagta ttcagaaact aacctatata aaatgtaaac aatatattga ttgcactata     4500

taaatgagta aattttgaga ggaacaatgt gggaatgtat aaatttgtct aaaattttat     4560

aactgttgaa caaagggaag atttgaacag tgtaaattcc agagttgaga aagcatttag     4620

catggtggaa atgtggagag cttattggtg agagaggatg gagctaagag aaataagatc     4680

aaatattaaa attaggaatt taggcattac ctcagggaaa agccttgaca gtgaaaagaa     4740

actacttaat cgctaatagc tagtctggac cagacactta actgcgcttt gggaatcatc     4800

ctgggctaat caggaaataa acttgacttt tctatttttc tctgaagctt tacaggacat     4860

actcccactc ccattttttt ctaagcctac agcatcttga ttcatagtat aattcctgaa     4920

gtatgctgaa tggacttttt aaggttcctt tagcattttt gtatagagtt atatgtgatc     4980

tttctataac catgccattc acttaaataa ttcatgaagg gaatggttta atttaaagga     5040

agacctaata ggaagaagat taaaggaagc ttttagtcag cctgtggcta gatttattga     5100

tttggtgatc aaacctgtgc tatttcctga atttcagcta atggccaact gtggtcaaag     5160

aatggctttc agttaaagtt ttgacttctt attataaata atataaagaa tgtctcagta     5220

attagaaatc ccttaataag tagaacaaat gtggcaagta ggactcctat cggtatacaa     5280

attccatttc tttttataag aaaaacacat aaaccattat catttattca tgagccaaag     5340

ccattaagaa gataaatcca gttatcagct tcctgtctct gaagtttgga tcattttata     5400

gatccacgca atagagagct tccttcctat gaaacaaaaa ccttgagatc tctttttttt     5460

tgagacagag tctcgctgtt gtcagcccag gctggagtgc aatggcgcaa tctcggttca     5520

ctgcaacctc tgccttccag gttccagcaa ttctcctacc tcagctccca agtagctgag     5580

atgacaggcg tgtgccacca cgcccagcta atttttgtat ttttagtagc gatggtgttt     5640

cactacattg gccaggctgg tctcgaactc ctgacctcag gtgaccaccc gcctcagcct     5700

cccaaagtgc tgggattaca ggcatgagcc actgtgcccg gccaagatct aactcacgct     5760

tacttttcat taaaatattt cttgtcgctt ttagctattg tcagaatcca ataaacagct     5820

tacgcattca ttttggtaaa gcaaatttca caggaaaata gacaaaatta taagagattc     5880

ctggagacaa cacaaggaaa acaatgttta aaagcaaaat agcctgtgta atgttaggta     5940

atgtaatgcc caagtgaata aaagattttt cgtcaagcaa actactgttt ctactttggg     6000

ggaaaaaagt cagttttaca tttgtaattt aaggaaagaa cagaaagcac aaaggttttt     6060

cttttcttta ttaatggcct actagaaatg agcagtgcaa gagtctacct gtactattct     6120

aatacagtaa gatattggac acaaaatgga ggtaactttt taaaatagat tggcttggaa     6180

gttgaaatgt agattaatgg atataaccca atagaaaggg attttcaaat aaaaccaaag     6240

tctatttttt tatttacttt ctaattttga acagatgact cagtcctaaa tctttgcctt     6300

tatttcctat aaaatgtagg tgatacttgt aactcgactt cctggagtta attcttcagc     6360

aagaggtgac cctgggagcg tactttaaaa taattgctgt acagccattg agtactaaca     6420

tgatgatagg ttttcaaaat atctttgtag tggatgctgc ataattacat tcacttctct     6480

tagactgtaa aagactttct tgacttgttt taacagtaga gatagcagta caatttgaat     6540

ttatggttta ggctctgcaa ttagaggaac aattgcagtt tcctcctacc cttcatatgg     6600

tctgtgtaaa actgatgttt gcttaactta ttttaaaagt tgattacgtt ttcagaaaat     6660

aaagataatc acttttgcca tggttataat caaatctaag ctttcagact tgagagccat     6720

ggtgtaaaac tcaaggaggt ttatttaaat tatgctgact ttgctagaat tggataaatt     6780

ctgtataagc caagtatgag ttcacatgta ctcgaatata cagttttcac aaagctatta     6840

ctctcatcag tcaggcttgt atgatctatt ccttaccaca aaagaagtag acaattgcca     6900

cttttatttc taatccttaa gttgaatgtt tcttcttgga tgtaagttca aataaattga     6960

tctggataaa ttttcatttc tacttaatta aaacttccta tgtaaaatcc aaaaaaaaaa     7020

aaaaaaaaa                                                             7029


<210>  1936
<211>  3715
<212>  DNA
<213>  homo sapiens

<400>  1936
atccacttgt acaaccagaa gggagctcac gtgtaaagcg cctcgtcccc ggccggcctc       60

aagcggcgct agctctctgg ctggcgctgg agtgtgccgc ccctggcagc cccgccgctg      120

cagcggggag cctgggagag cggctctcgg agtctcaggc agcaggagga gcgtgtgagc      180

tgtgggcgtc cctttaagag cggctggcca ggcacggcct ccgcctctca gtacgcggag      240

cgccggcggt cacctggggc tcgcggagcg gccagatcgc ggcggagtcg gcgcgcttcc      300

ccgagggaag gtgggagagg ggacccggac gcgaggtgcc ccgaagccct ctcgagcgta      360

accgtcccgc gcctctctga ggcggaggat gcgggagcgc atctgggcgc cgccgctgct      420

gctgctgctg ccgctgctac tgccgccgcc actgtggggc ggccccccgg acagcccacg      480

ccgggagctg gagctggagc ccgggcctct gcagcccttc gacctgctct acgccagcgg      540

cgcggccgcc tactacagcg gagactacga gcgagcggtg cgcgacttgg aagcggcgct      600

gcgcagccac cggcgcctgc gggaaatccg cacgcgctgt gcccgccact gcgcggcgcg      660

ccacccgctc ccgcccccgc cccccggcga gggccccggc gctgagctgc cccttttccg      720

ctccttgttg gggcgggcgc gctgttatcg cagctgtgag acccagcgcc tcgggggccc      780

cgcatcccgc caccgcgtca gcgaggatgt gcgcagcgac ttccagcgca gagtgcccta      840

caactacctg cagcgggcct acatcaagct taaccagctc gaaaaagcag tggaagcagc      900

tcacacattt ttcgtggcta accctgagca catggaaatg cagcagaaca ttgagaatta      960

cagggcgaca gctggtgttg aagcattgca gttggtagac agagaagcca agccacacat     1020

ggagagttac aatgcaggag ttaaacatta tgaggctgat gactttgaga tggctatcag     1080

gcacttcgaa caagccttaa gagaatattt cgttgaagat acagaatgcc ggaccctatg     1140

tgaggggcct cagagatttg aagaatatga gtatttaggg tataaggctg gtctgtatga     1200

agctattgca gatcactaca tgcaggtgct tgtttgtcag catgaatgtg tgagggaact     1260

tgccacccgc cctggccgcc tctctcccat cgagaatttt cttcctctgc actatgatta     1320

cctacagttt gcctactatc gagttggtga gtatgtgaaa gccctggagt gtgccaaagc     1380

ctatcttcta tgccatccag atgatgagga tgtcctagac aatgtggatt actatgagag     1440

tctgctggat gatagcattg acccggcatc cattgaggcc agagaggatt taacaatgtt     1500

tgtgaaacgt cataagctgg agtctgagct gataaaatca gctgcagaag gtctggggtt     1560

ttcatacact gaaccgaatt attggatcag atatggagga cgacaggatg agaatcgggt     1620

cccttcagga gtgaacgtag agggagcaga agttcatgga ttctcaatgg gaaaaaagct     1680

atcacccaag atagatcgag acctaagaga aggtggtcct ctactctatg agaacatcac     1740

attcgtctac aactcggagc agctgaacgg gactcagcgg gttctcctgg ataacgtcct     1800

gtcggaagaa cagtgccggg agctccacag cgtggccagt ggaatcatgc ttgttggtga     1860

tggatacaga ggaaaaactt caccccatac acccaatgaa aagtttgaag gtgcaactgt     1920

cctgaaagca ctcaaatctg gttatgaagg tcgagtccca ctgaagagcg ctcgtctgtt     1980

ttatgacatc agcgaaaagg ctcgaaggat tgtagaatct tattttatgc tgaactcaac     2040

tctgtatttt tcctatacac acatggtctg ccgaacagcc ctgtctggtc agcaggatag     2100

aagaaatgac ctcagtcatc ccatccatgc tgacaactgt ttgttggatc cagaggccaa     2160

cgaatgctgg aaggagcctc ctgcttacac atttcgagac tatagtgctc tcctatatat     2220

gaatgatgac tttgaaggag gagaattcat attcacagag atggatgcta agactgtgac     2280

tgcctctata aaaccaaaat gtgggcgcat gatcagcttc tcatctggag gagagaaccc     2340

tcatggggtg aaggcagtca ccaagggaaa gaggtgtgct gtggctctgt ggttcacctt     2400

ggacccactt tatagagaat tggagcgaat acaggctgat gaagtgattg caattctgga     2460

tcaagaacag caagggaagc atgaactgaa tatcaaccct aaagatgagc tataaaaatg     2520

agaaagaatg ttctatcaaa tatttattta aattgttaat cttatgagaa cctttttatt     2580

tttgtacaga gccatggtat aaattaacag gttaatgtca gtcatcagat cttccttctc     2640

ttcctaagga tgcttgtgtt gcctcaatct atcaatctat ctttcttgtt ttgggttgtt     2700

ttctctctct ctctctctct ctctcttctt agagacatgg tctaaccatg ttgtctagga     2760

tatagggcag tggctattca cagatgtgat gatagcacac tggagcctca aactcttagg     2820

ctcaggcgat ccttcaagcc tcccggggag ctgggaccac aggcacgtgc caccacaccc     2880

agctctcttt cttggttttt catcatttca tgtatctatc aaagcccagt tcacctcctc     2940

ccccaaacac acacacacac acacacacac acacacacac acacaattaa gttgctgcaa     3000

attcaaaagc ttagagagaa taagcttctt ggtggtgaaa ctacaactct cacgtgtgct     3060

ccagttctaa aattaacctg tgcctggtct ctgaagccct ttcttgctct gtgcctttca     3120

gccacatcct taggtgctaa cggccatgag ctccgactct ccaaagtgag ctccactttg     3180

ggtctgagga gcccctggca gagtccacgc tgcctcaggt atcatgggcg taatgatcac     3240

ccaggctccg ggagatctca tggatgatta ctgtatgaga cagaggggac ttcagtcttt     3300

ccagggcctt ggtggaattt ttggctctgg tgttttcgcc agacaataaa cttacactgg     3360

aagctttgat tcaccctcca cagtactcca gaaaggactg tcctataagt tgtacacttt     3420

aaaaggtcat gtagaggttg tagtagaatg gcttttcacc ctggtgactt tggaagaaac     3480

tcttgaatac tgcctgcatc cgggcaccat ggccaggttg cctaggagtg gggtccactg     3540

atgaaaagag gtgttttgta cttacataag aaaaataaat ttctgattga ttttaaccgt     3600

catctgctta tattttgggg gcccctcctc attgctgcta tccagcacac agatttgtgc     3660

ttgtgtctga tttgtttaat aaagggaggc ttattttaaa aaaaaaaaaa aaaaa          3715


<210>  1937
<211>  4078
<212>  DNA
<213>  homo sapiens

<400>  1937
ggtttccagg cctgaggtgc ccgccctggc cccaggagaa tgaaccagcc gcagaggatg       60

gcgcctgtgg gcacagacaa ggagctcagt gacctcctgg acttcagcat gatgttcccg      120

ctgcctgtca ccaacgggaa gggccggccc gcctccctgg ccggggcgca gttcggaggt      180

tcaggtcttg aggaccggcc cagctcaggc tcctggggca gcggcgacca gagcagctcc      240

tcctttgacc ccagccggac cttcagcgag ggcacccact tcactgagtc gcacagcagc      300

ctctcttcat ccacattcct gggaccggga ctcggaggca agagcggtga gcggggcgcc      360

tatgcctcct tcgggagaga cgcaggcgtg ggcggcctga ctcaggctgg cttcctgtca      420

ggcgagctgg ccctcaacag ccccgggccc ctgtcccctt cgggcatgaa ggggacctcc      480

cagtactacc cctcctactc cggcagctcc cggcggagag cggcagacgg cagcctagac      540

acgcagccca agaaggtccg gaaggtcccg ccgggtcttc catcctcggt gtacccaccc      600

agctcaggtg aggactacgg cagggatgcc accgcctacc cgtccgccaa gacccccagc      660

agcacctatc ccgccccctt ctacgtggca gatggcagcc tgcacccctc agccgagctc      720

tggagtcccc cgggccaggc gggcttcggg cccatgctgg gtgggggctc atccccgctg      780

cccctcccgc ccggtagcgg cccggtgggc agcagtggaa gcagcagcac gtttggtggc      840

ctgcaccagc acgagcgtat gggctaccag ctgcatggag cagaggtgaa cggtgggctc      900

ccatctgcat cctccttctc ctcagccccc ggagccacgt acggcggcgt ctccagccac      960

acgccgcctg tcagcggggc cgacagcctc ctgggctccc gagggaccac agctggcagc     1020

tccggggatg ccctcggcaa agcactggcc tcgatctact ccccggatca ctcaagcaat     1080

aacttctcgt ccagcccttc tacccccgtg ggctcccccc agggcctggc aggaacgtca     1140

cagtggcctc gagcaggagc ccccggtgcc ttatcgccca gctacgacgg gggtctccac     1200

ggcctgcaga gtaagataga agaccacctg gacgaggcca tccacgtgct ccgcagccac     1260

gccgtgggca cagccggcga catgcacacg ctgctgcctg gccacggggc gctggcctca     1320

ggtttcaccg gccccatgtc actgggcggg cggcacgcag gcctggttgg aggcagccac     1380

cccgaggacg gcctcgcagg cagcaccagc ctcatgcaca accacgcggc cctccccagc     1440

cagccaggca ccctccctga cctgtctcgg cctcccgact cctacagtgg gctagggcga     1500

gcaggtgcca cggcggccgc cagcgagatc aagcgggagg agaaggagga cgaggagaac     1560

acgtcagcgg ctgaccactc ggaggaggag aagaaggagc tgaaggcccc ccgggcccgg     1620

accagcagta cggacgaggt gctgtccctg gaggagaaag acctgaggga ccgggagagg     1680

cgcatggcca ataacgcgcg ggagcgggtg cgcgtgcggg atattaacga ggccttccgg     1740

gagctggggc gcatgtgcca gatgcacctc aagtcggaca aagcgcagac caagctgctc     1800

atcctgcagc aggccgtgca ggtcatcctg gggctggagc agcaggtgcg agagcggaac     1860

ctgaatccca aagcagcctg tttgaaacgg cgagaagagg aaaaggtgtc aggtgtggtt     1920

ggagaccccc agatggtgct ttcagctccc cacccaggcc tgagcgaagc ccacaacccc     1980

gccgggcaca tgtgaaagta aacaaaacct gaaagcaagc aacaaaacat acactttgtc     2040

agagaagaaa aaaatgcctt aactataaaa agcggagaaa tggaaacata tcactcaagg     2100

gggatgctgt ggaaacctgg cttattcttc taaagccacc agcaaattgt gcctaagcga     2160

aatatttttt ttaaggaaaa taaaaacatt agttacaaga tttttttttt cttaatgtag     2220

atgaaaatta gcaaggatgc tgcctttggt ctctggtttt tttaagcttt ttttgcatat     2280

gttttgtaag caacaaattt ttttgtataa aagtcccgtg tctctcgcta tttctgctgc     2340

tgttcctaga ctgagcattg catttcttga tcaaccagat gattaaacgt tgtattaaaa     2400

agaccccgtg taaacctgag cccccccgtc cccccccccc cccggaagcc actgcacaca     2460

gacagaacgg ggacaggcgg cgggtctttt gtttttttga tgttgggggt tctcttggtt     2520

ttgtcatgtg gaaagtgatg cgtgggcgtt ccctgatgaa ggcaccttgg ggcttccctg     2580

ccgcatcctc tcccctcagg aaggggactg acctgggctt gggggaaggg acgtcagcaa     2640

ggtggctctg accctcccag gtgactctgc caagcagctg tggcccccag ggctacccta     2700

cacaacgccc tccccaggcc cccctaagct gctctccctt ggaacctgca cagctctctg     2760

aaatggggca ttttgttggg accagtgacc cctggcatgg ggaccacacc ctggagcccg     2820

gtgctgggga cctcctggac accctgtcct tcactccttt gccccaggga cccaggctca     2880

tgctctgaac tctggctgag aggatgctgc tcaggagcca gcacaggaca ccccccaccc     2940

caccccacca tgtccccatt acaccagagg gccatcgtga cgtagacagg atgccagggg     3000

cctggccagc ctcccccaat gctggggagc atccctgggc ctggggccac acctgctgcc     3060

ctccctctgt gtggtccaag ggcaagagtg gctggagccg ggggactgtg ctggtctgag     3120

ccccacgaag gccttgggct gtgcgtccga ccctgctgca gaaccagcag ggtgtcccct     3180

cgggcccatc tgtgtcccat gtcccagcac ccaggcctct ctccaggtct ccttttctgg     3240

tcttttgcca tgagggtaac cagctcttcc cagctggctg gggactgtct tgggtttaaa     3300

actgcaagtc tcctaccctg ggatcccatc cagttccaca cgaactaggg cagtggtcac     3360

tgtggcaccc aggtgtgggc ctggctagct gggggccttc atgtgccctt catgcccctc     3420

cctgcattga ggccttgtgg acccctgggc tggctgtgtt catccccgct gcaggtcggg     3480

cgtctccccc cgtgccactc ctgagactcc caccgttacc cccaggagat cctggactgc     3540

ctgactcccc tccccagact ggcttgggag cctgggcccc atggtagatg caagggaaac     3600

ctcaaggcca gctcaatgcc tggtatctgc ccccagtcca ggccaggcgg aggggagggg     3660

ctgtccggct gcctctccct tctcggtggc ttcccctacg ccctgggagt ttgatctctt     3720

aagggaactt gcctctccct cttgttttgc tcctggccct gcccctaggt ctgggtgggc     3780

agtggcccca tagcctctgg aactgtgcgt tctgcataga attcaaacga gattcaccca     3840

gcgcgaggag gaagaaacag cagttcctgg gaaccacaat tatggggggt ggggggtgtg     3900

atctgagtgc ctcaagatgg ttttcaaaaa aattttttta aagaaaataa ttgtatacgt     3960

gtcaacacag ctggctggat gattgggact ttaaaacgac cctctttcag gtggattcag     4020

agacctgtcc tgtatataac agcactgtag caataaacgt gacattttat aacgatgc       4078


<210>  1938
<211>  2666
<212>  DNA
<213>  homo sapiens

<400>  1938
aagattatag agacttgctt tagaaccaca agaagaaaga ggaggccggc ttttcagcta       60

gcatcatggc gtggccgtgc atcacgaggg cctgctgcat cgcccgcttc tggaaccagt      120

tggacaaagc ggacatcgct gtgccgctgg ttttcaccaa gtactcggag gccaccgagc      180

acccgggcgc cccgccgcag ccaccgccgc cgcagcagca ggcgcagccg gcgctcgcgc      240

ccccctcggc gcgcgcggtt gccatagaga cgcagccagc ccagggcgag ttggatgcag      300

ttgcccgggc aacggggcca gcgcctgggc ctaccggcga gcgcgagccg gcggcgggcc      360

ccggccggag cgggccgggc ccgggcctgg gctccggctc cacctccggc cccgcggact      420

cggtgatgcg gcaggattac cgagcctgga aggtgcagcg gcccgagccc agctgccggc      480

cgcgcagcga ataccagccc tccgacgctc ccttcgagcg cgagacccag taccagaagg      540

acttccgcgc ctggccgctg ccgcgccgcg gggaccaccc gtggatcccc aagcccgtgc      600

agatctctgc ggcctcccag gcgtcggcgc ccattctcgg ggcgcccaag cgccggccgc      660

agagccagga gcgctggcca gtgcaggccg ccgctgaggc ccgggagcag gaggcggccc      720

ccggcggagc gggtggcctg gcggccggaa aggcgtccgg ggcggacgag cgcgacacgc      780

gcaggaaggc cgggcctgcc tggattgtgc gccgcgccga gggcctgggg cacgagcaga      840

cgccgctgcc cgcggcccag gcccaggtcc aggccaccgg ccccgaggct ggcagggggc      900

gcgccgcggc ggacgccctc aaccggcaaa tccgcgagga ggtggcgagt gcagtgagca      960

gctcctacag gaatgaattc agggcatgga cggacatcaa gcctgtgaaa ccaataaagg     1020

ccaagcccca gtacaagccc ccagatgata agatggttca tgagaccagc tacagtgctc     1080

agttcaaagg agaggccagc aagccaacaa cagctgacaa taaggtcatt gatcgcagaa     1140

gaatacgcag cctctacagc gaacccttca aggaaccccc aaaggtggaa aaacctagtg     1200

ttcagagttc caaaccaaaa aagacctcag cgagccataa gcccacgagg aaggccaaag     1260

acaagcaggc ggtgtcaggc caggctgcca agaaaaagag cgcggagggc ccgagtacca     1320

ccaagccaga cgacaaggag caaagcaaag agatgaacaa taaactggct gaggcgaaag     1380

agagcctggc tcaacccgtc agtgattcaa gtaagactca aggtcctgta gccacagagc     1440

cagacaagga tcaaggttct gtggtcccag gccttctgaa aggtcaaggt cctatggtgc     1500

aagagcctct gaagaagcaa ggttctgtgg tcccagggcc tccaaaggat ctaggtccca     1560

tgatcccatt accagtcaag gatcaagatc acacggtccc tgagccttta aagaatgaaa     1620

gccctgttat ctcagcacca gtcaaggacc aaggtccctc ggtcccagtt cctccaaaga     1680

atcaaagtcc tatggttcca gcaaaagtta aggatcaagg ctctgtggta ccagagtctc     1740

taaaggatca aggtcctagg attcctgagc ctgtgaagaa tcaagctcct atggtcccag     1800

cacctgtcaa ggatgaaggt cccatggtct cagcatctgt caaggatcaa ggtcccatgg     1860

tctcagcacc tgtcaaggat caaggtccca tagtcccagc acctgtcaag ggtgaaggtc     1920

ccatagtccc agcacctgtc aaggatgaag gtcccatggt ctcagcacct atcaaggatc     1980

aagatcccat ggtcccagag catccgaagg atgaaagtgc catggccaca gcacccataa     2040

agaatcaagg ttccatggtc tctgagcctg taaagaatca aggtttagtg gtctcagggc     2100

cagtcaagga tcaagatgtt gtagtcccag agcatgcaaa ggttcacgat tctgcagttg     2160

tggcacctgt aaagaatcaa ggtcctgtgg tccccgagtc cgtgaagaat caagacccca     2220

ttctcccagt actagttaag gatcaaggcc ccacagtcct acagcctcca aagaatcaag     2280

gtcgtatagt ccctgaacct ctgaagaatc aagttcctat agtcccagtg cctctgaagg     2340

atcaagatcc tctggtgcca gtaccagcaa aggaccaagg tcctgcagtc cctgaacctc     2400

tgaagactca aggtcccagg gaccctcagc tacctactgt ctcacctcta ccccgagtca     2460

tgatcccaac tgccccccat acggaataca ttgagagctc cccttgacac tcaccccttg     2520

acacaccaat gaaggagctg acagtgagag tgctcccctc ccaggggcag tgaagacaca     2580

tatttaatct gcatgaaaca tgtacagtag tcttgctgga atctaataaa aatggtccct     2640

ctggctcaaa aaaaaaaaaa aaaaaa                                          2666


<210>  1939
<211>  4322
<212>  DNA
<213>  homo sapiens

<400>  1939
attcatctgt gcacttgggc gttggacccc gcatcttatt agcaaccagg gagatttctc       60

cattttcctc ttgtctacag tgcggctaca aatctgggat ttttttatta cttctttttt      120

tttcgaacta cacttgggct cctttttttg tgctcgactt ttccaccctt tttccctccc      180

tcctgtgctg ctgctttttg atctcttcga ctaaaatttt tttatccgga gtgtatttaa      240

tcggttctgt tctgtcctct ccaccacccc cacccccctc cctccggtgt gtgtgccgct      300

gccgctgttg ccgccgccgc tgctgctgct gctcgccccg tcgttacacc aacccgaggc      360

tctttgtttc ccctcttgga tctgttgagt ttctttgttg aagaagccag catgggtgcc      420

cagttctcca agaccgcagc gaagggagaa gccgccgcgg agaggcctgg ggaggcggct      480

gtggcctcgt cgccttccaa agcgaacgga caggagaatg gccacgtgaa ggtaaacggc      540

gacgcttcgc ccgcggccgc cgagtcgggc gccaaggagg agctgcaggc caacggcagc      600

gccccggccg ccgacaagga ggagcccgcg gccgccggga gcggggcggc gtcgccctcc      660

gcggccgaga aaggtgagcc ggccgccgcc gctgcccccg aggccggggc cagcccggta      720

gagaaggagg cccccgcgga aggcgaggct gccgagcccg gctcgcccac ggccgcggag      780

ggagaggccg cgtcggccgc ctcctcgact tcttcgccca aggccgagga cggggccacg      840

ccctcgccca gcaacgagac cccgaaaaaa aaaaagaagc gcttttcctt caagaagtct      900

ttcaagctga gcggcttctc cttcaagaag aacaagaagg aggctggaga aggcggtgag      960

gctgaggcgc ccgctgccga aggcggcaag gacgaggccg ccgggggcgc agctgcggcc     1020

gccgccgagg cgggcgcggc ctccggggag caggcagcgg cgccgggcga ggaggcggca     1080

gcgggcgagg agggggcggc gggtggcgac ccgcaggagg ccaagcccca ggaggccgct     1140

gtcgcgccag agaagccgcc cgccagcgac gagaccaagg ccgccgagga gcccagcaag     1200

gtggaggaga aaaaggccga ggaggccggg gccagcgccg ccgcctgcga ggccccctcc     1260

gccgccgggc ccggcgcgcc cccggagcag gaggcagccc ccgcggagga gcccgcggcc     1320

gccgcagcct cgtcagcctg cgcagccccc tcacaggagg cccagcccga gtgcagtcca     1380

gaagcccccc cagcggaggc ggcagagtaa aagagcaagc ttttgtgaga taatcgaaga     1440

acttttctcc cccgtttgtt tgttggagtg gtgccaggta ctggttttgg agaacttgtc     1500

tacaaccagg gattgatttt aaagatgtct ttttttattt tacttttttt taagcaccaa     1560

attttgttgt tttttttttt tctcccctcc ccacagatcc catctcaaat cattctgtta     1620

accaccattc caacaggtcg aggagagctt aaacaccttc ttcctctgcc ttgtttctct     1680

tttatttttt attttttcgc atcagtatta atgtttttgc atactttgca tctttattca     1740

aaagtgtaaa ctttctttgt caatctatgg acatgcccat atatgaagga gatgggtggg     1800

tcaaaaaggg atatcaaatg aagtgatggg gtcacaatgg ggaaattgaa gtggtgcata     1860

acattgccaa aatagtgtgc cactagaaat ggtgtaaagg ctgtcttttt ttttttttta     1920

aaagaaaagt tattaccatg tattttgtga ggcaggttta caacactaca agtcttgagt     1980

taagaaggaa agaggaaaaa agaaaaaaca ccaataccca gatttaaaaa aaaaaaaacg     2040

atcatagtct taggagttca tttaaaccat aggaactttt cacttatctc atgttagctg     2100

taccagtcag tgattaagta gaactacaag ttgtataggc tttattgttt attgctggtt     2160

tatgacctta ataaagtgta attatgtatt accagcaggg tgtttttaac tgtgactatt     2220

gtataaaaac aaatcttgat atccagaagc acatgaagtt tgcaactttc caccctgccc     2280

atttttgtaa aactgcagtc atcttggacc ttttaaaaca caaattttaa actcaaccaa     2340

gctgtgataa gtggaatggt tactgtttat actgtggtat gtttttgatt acagcagata     2400

atgctttctt ttccagtcgt ctttgagaat aaaggaaaaa aaatcttcag atgcaatggt     2460

tttgtgtagc atcttgtcta tcatgttttg taaatactgg agaagctttg accaatttga     2520

cttagagatg gaatgtaact ttgcttacaa aaattgctat taaactcctg cttaaggtgt     2580

tctaattttc tgtgagcaca ctaaaagcga aaaataaatg tgaataaaat gtacaaattt     2640

gttgtgtttt tttatgttct aataatactg agacttctag gtcttaggtt aatttttagg     2700

aagatcttgc atgccatcag gagtaaattt tattgtggtt cttaatctga agttttcaag     2760

ctctgaaatt cataatccgc agtgtcagat tacgtagagg aagatcttac aacatttcca     2820

tgtcaaatct gttaccattt attggcattt agttttcatt taagaattga acataattat     2880

ttttattgta gctatatagc atgtcagatt aaatcattta caacaaaagg ggtgtgaacc     2940

taagactatt taaatgtctt atgagaaaat ttcataaagc cattctcttg tcattcaggt     3000

ccagaaacaa attttaaact gagtgagagt ctatagaatc catactgcag atgggtcatg     3060

aaatgtgacc aaatgtgttt caaaaattga tggtgtatta cctgctattg taattgctta     3120

gtgcttggct aatttccaaa ttattgcata atatgttcta ccttaagaaa acaggtttat     3180

gtaacaaagt aatggtgttg aatggatgat gtcagttcat gggcctttag catagtttta     3240

agcatccttt tttttttttt tttttgaaag tgtgttagca tcttgttact caaaggataa     3300

gacagacaat aatacttcac tgaatcttaa taatctttac tagtttacct cctctgctct     3360

ttgccacccg ataactggat atcttttcct tcaaaggacc ctaaactgat tgaaatttaa     3420

gatatgtatc aaaaacatta tttcatttaa tgcacatctg ttttgctgtt tttgagcagt     3480

gtgcagttta gggttcatga taaatcattg aaccacatgt gtaacaactg aatgccaaat     3540

cttaaactca ttagaaaaat aacaaattag gttttgacac gcattcttaa ttggaataat     3600

ggatcaaaaa tagtggttca tgaccttacc aaacaccctt gctactaata aaatcaaata     3660

acacttagaa gggtatgtat ttttagttag ggtttcttga tcttggagga tgtttgaaag     3720

ttaaaaattg aatttggtaa ccaaaggact gatttatggg tctttcctat cttaaccaac     3780

gttttcttag ttacctagat ggccaagtac agtgcctggt atgtagtaag actcagtaaa     3840

aaagtggatt tttaaaaata actcccaaag tgaatagtca aaaatcctgt tagcaaactg     3900

ttatatattg ctaagtttgt tcttttaaca gctggaattt attaagatgc attattttga     3960

ttttattcac tgcctaaaac actttgggtg gtattgatgg agttggtgga ttttcctcca     4020

agtgattaaa tgaaatttga cgtatctttt catccaaagt tttgtacatc atgttttcta     4080

acggaaaaaa atgttaatat ggcttttttg tattactaaa aatagctttg agattaagga     4140

aaaataaata actcttgtac agttcagtat tgtctattaa atctgtattg gcagtatgta     4200

taatggcatt tgctgtggtt acaaaatact tcctctgggt tataataatc atttgatcca     4260

attcctattg cttgtaaaat aaagttttac cagttgatat aatcaaaaaa aaaaaaaaaa     4320

aa                                                                    4322


<210>  1940
<211>  5336
<212>  DNA
<213>  homo sapiens

<400>  1940
gctgctccgc gcgcagccgg ctcgggccgc tcctcctgac tgaggcgcgg cggcggcggt       60

ggctgtgacc gcgcggaccg agccgagaca ttcgcgccgg gggatcgggc gccgccgccg      120

ctgggccccg ggcgcgtgga tgcggctggg tcgggcggcg ccgtacacct gaggcggaga      180

acggggcgcg gcgcgggtga cgctgtcagg gccgcggttc ctgacgccca ggcgctcgcc      240

aggacgagcc aggcagtgat ttgaggcacc ggcttcacct tcacccatgg tccggagagc      300

ctagcggggc tcgccaccgc ctcccggctc cccttccacg cctcatcctg ccagcctcgc      360

cgccccgcca gcgccgggca accgcctcgc ccgaagccct ccctcgttac tgtccgcata      420

ccccggcggc gccgccgcgg gaagcggctc cccctcctct tcctccgcgt cctcttccct      480

ctttcccccg ccggggccgc ttgttgcacc gccccgcggc ctgcgggagc cgctcgcccc      540

ggccttgtgc tcgcgtccgc acccctttcc tgtcgccccc cggggcccgc accacagccc      600

ggccggcgag accccggcca gaccccgctg cccgcacaaa atgtcggccc ggacgccatt      660

gccgacggtg aacgagcggg acacggaaaa tcatacatct gtggatggat atactgaacc      720

acacatccag cctaccaagt cgagtagcag acagaacatc ccccggtgta gaaactccat      780

tacgtcagca acagatgaac agcctcacat tggaaattac cgtttacaaa aaacaatagg      840

gaagggaaat tttgccaaag tcaaattggc aagacacgtt ctaactggta gagaggttgc      900

tgtgaaaata atagacaaaa ctcagctaaa tcctaccagt ctacaaaagt tatttcgaga      960

agtacgaata atgaagatac tgaatcatcc taatatagta aaattgtttg aagttattga     1020

aacagagaag actctctatt tagtcatgga atacgcgagt gggggtgaag tatttgatta     1080

cttagttgcc catggaagaa tgaaagagaa agaggcccgt gcaaaattta ggcagattgt     1140

atctgctgta cagtattgtc atcaaaagta cattgttcac cgtgatctta aggctgaaaa     1200

ccttctcctt gatggtgata tgaatattaa aattgctgac tttggtttta gtaatgaatt     1260

tacagttggg aacaaattgg acacattttg tggaagccca ccctatgctg ctcccgagct     1320

tttccaagga aagaagtatg atgggcctga agtggatgtg tggagtctgg gcgtcattct     1380

ctatacatta gtcagtggct ccttgccttt cgatggccag aatttaaagg aactgcgaga     1440

gcgagtttta cgagggaagt accgtattcc cttctatatg tccacagact gtgaaaatct     1500

tctgaagaaa ttattagtcc tgaatccaat aaagagaggc agcttggaac aaataatgaa     1560

agatcgatgg atgaatgttg gtcatgaaga ggaagaacta aagccatata ctgagcctga     1620

tccggatttc aatgacacaa aaagaataga cattatggtc accatgggct ttgcacgaga     1680

tgaaataaat gatgccttaa taaatcagaa gtatgatgaa gttatggcta cttatattct     1740

tctaggtaga aaaccacctg aatttgaagg tggtgaatcg ttatccagtg gaaacttgtg     1800

tcagaggtcc cggcccagta gtgacttaaa caacagcact cttcagtccc ctgctcacct     1860

gaaggtccag agaagtatct cagcaaatca gaagcagcgg cgtttcagtg atcatgctgg     1920

tccatccatt cctcctgctg tatcatatac caaaagacct caggctaaca gtgtggaaag     1980

tgaacagaaa gaggagtggg acaaagatgt ggctcgaaaa cttggcagca caacagttgg     2040

atcaaaaagc gagatgactg caagccctct tgtagggcca gagaggaaaa aatcttcaac     2100

tattccaagt aacaatgtgt attctggagg tagcatggca agaaggaata catatgtctg     2160

tgaaaggacc acagatcgat acgtagcatt gcagaatgga aaagacagca gccttacgga     2220

gatgtctgtg agtagcatat cttctgcagg ctcttctgtg gcctctgctg tcccctcagc     2280

acgaccccgc caccagaagt ccatgtccac ttctggtcat cctattaaag tcacactgcc     2340

aaccattaaa gacggctctg aagcttaccg gcctggtaca acccagagag tgcctgctgc     2400

ttccccatct gctcacagta ttagtactgc gactccagac cggacccgtt ttccccgagg     2460

gagctcaagc cgaagcactt tccatggtga acagctccgg gagcgacgca gcgttgctta     2520

taatgggcca cctgcttcac catcccatga aacgggtgca tttgcacatg ccagaagggg     2580

aacgtcaact ggtataataa gcaaaatcac atccaaattt gttcgcaggg atccaagtga     2640

aggcgaagcc agtggcagaa ccgacacctc aagaagtaca tcaggggaac caaaagaaag     2700

agacaaggaa gagggtaaag attctaagcc gcgttctttg cggttcacat ggagtatgaa     2760

gaccactagt tcaatggacc ctaatgacat gatgagagaa atccgaaaag tgttagatgc     2820

aaataactgt gattatgagc aaaaagagag atttttgctt ttctgtgtcc atggagacgc     2880

tagacaggat agcctcgtgc agtgggagat ggaagtctgc aagttgccac gactgtcact     2940

taatggggtt cgcttcaagc gaatatctgg gacatctatt gcctttaaga acattgcatc     3000

aaaaatagca aatgagctta agctgtaaag aagtccaaat ttacaggttc agggaagata     3060

catacatata tgaggtacag tttttgaatg tactggtaat gcctaatgtg gtctgcctgt     3120

gaatctcccc atgtagaatt tgcccttaat gcaataaggt tatacatagt tatgaactgt     3180

aaaattaaag tcagtatgaa ctataataaa tatctgtagc ttaaaaagta ggttcacatg     3240

tacaggtaag tatattgtgt atttctgttc attttctgtt catagagttg tataataaaa     3300

catgattgct taaaaacttg tatagttgtc tagatttctg cacctgaatg tatgtttgat     3360

gctttgattt gaaaatgttc ttccctgtta tttacattct ggtgggtttt taaaattctt     3420

acctccatca tgcaattttg aaaattgtgt ccagaattaa aagtgcatag aaatagcctt     3480

tacaattgta gcatggacct ttaaaaattg ttttaaaatc ttatttaaat ttaaaccaga     3540

agctgaaaaa tagatcagct ttattataca caaaattatt actgcttatc tttgctcttt     3600

tccttgttat cccgcaaggt ttagttgaga agatacaaaa tgtttacagt gttggcactt     3660

agagttttta aattcaagta catgaaattc agtaatagca ttgccttgag ctaactagga     3720

agtaccggga aaaaagttaa atctacatca agtttctttt gaactttgaa gtgttttctg     3780

acccactgct aactgtagca acaaaattta aaagaaaaaa aacatacttt atctggctat     3840

tataacataa actgtcacgt aggtttgctg ccttcagaat accgcaattt aattgcggga     3900

atataataat attgggactg tttcacagca caaactcatc tttacagtgt tgatcaatgc     3960

atcagttaag aaataatgcc acctcaggaa ttaactggca ttgggaacat ttgcctcatt     4020

ctcctgctat cctcttcatt cacccctgcc actgtaatat ctataagtac ttaagagact     4080

tgtgagcaaa acatactatt tataacagta tatgattgat ttatgcttat gtggttgttc     4140

agtttgttcc catgtaactc gtttgtttta aatattttgc cagatttctt gtatttattc     4200

cacatcatta tgcctataat gtgccgcttt gtgattgggc atttgcctac ttttctttca     4260

taattagtga tatatgcgat gtaaaaccac tagtaaaggt acattttaat acttgttatt     4320

ttatactgaa ttagccttgg aggttgactg tgcaatgtta tttactgttg taattactgt     4380

aataccaaca tatgggcccc atctgcacac tcctgaaaaa cagaaagtgt attcaaattt     4440

tatcagttta aagaaaataa agctgtgata aatactgtaa ttccaaccta cattagaagg     4500

tctaagtgta ggtgatgtgc cattccataa tggcttccag actagggtga attttatgtt     4560

ctgtactgta ctgtgatgta gctttcttct gtaacagtta tgttttaaaa ttaagtgagt     4620

tttttttttg ccttagcaaa gggtggtgtt tgaaaaaaaa aatgtgtagc ccctttttaa     4680

cctagtgttc attcaaaaaa aaattgatgc aaatctttat tcactttcac tggtgcacac     4740

tgaaatttta cttgaacagt tctcataata aagcacttgt cttttgctct ttatcagaat     4800

gtgaattacc tgttttctgg tacaaaagta ttctgtatga ggagtttatt gtatgtgttc     4860

taaatttagt tggcaaaggg tgaagctgtg aaggttttca agattattga aactatgaag     4920

gtttcttgtc attatgacaa gaaagtttaa tctttttata ggaattcctg tcactgaaat     4980

acgtttttaa aaaaatagac tcatgtgttt tccacggtag aaactgatat ttttttacat     5040

tttctcactg tggccaactc ttctgtgttt gtagaaagga atttgacttc aatatctttt     5100

atgaactaaa aatgaaatct tgatactcac tttagatttt tcattttatg tgttcatgac     5160

aacataaata tttttcaaag atttagagga attttgcaat gtgtttgcat aaataaatac     5220

cagtttatgt tcaccggcta tgtgatacca ggatttcctt ggcttctgtt gaaatattat     5280

ttgatatgac atcccttata ttaaattaat tattttgtaa aaaaaaaaaa aaaaaa         5336


<210>  1941
<211>  1876
<212>  DNA
<213>  homo sapiens

<400>  1941
ggggaatcct gctctgggat agcacccggc cccgcagagc agcgcggcag cccaagggcc       60

ccggcgccgg gggcggcggg gaaccccaaa cgcaaccggg tctggaggga tccccgcgcc      120

gagccagccg ccgtcaccgc ctccgcgccg cccctgcggg cttggcaggc gcccggcgcg      180

cccgcactgc gcccggccgc cggctcccgc ggtcccaccg tgagctcgcc ggcccgtcgc      240

ccgctcgcca tgcaaccgcc gccggcctcg cgcgcgtagg cgcccgccgc aggccatgct      300

gcccctgctc gccgcgctcc tggccgccgc ctgcccgctg ccgcccgtcc gcggcggggc      360

cgcggacgcg cccggcctcc tcggggtgcc ctccaatgct tcagtcaacg cgtcctccgc      420

ggacgagccc atcgccccgc ggctgctggc ctcggcggcc cccgggcccc ccgagcgccc      480

gggcccggag gaggcggcgg cggcggcggc gccgtgcaac atcagcgtgc agcggcagat      540

gctgagctcg ctgctcgtgc gctggggccg cccgcggggc ttccagtgcg acctactgct      600

cttctccacc aacgcgcacg gccgcgcttt cttcgccgcc gccttccacc gcgtcgggcc      660

gccgctgctc atcgagcacc tggggctggc ggcgggcggc gcgcagcagg acctgcgcct      720

ctgcgtgggc tgcggctggg tgcgcggtcg ccgcaccggc cgcctccggc ccgccgccgc      780

ccccagcgcc gccgccgcca ccgccggggc gcccaccgcg ctgccagcct accccgcggc      840

cgagccgccc gggccgctgt ggctgcaggg cgagccgctg catttctgct gcctagactt      900

cagcctggag gagctgcagg gcgagccggg ctggcggctg aaccgtaagc ccattgagtc      960

cacgctggtg gcctgcttca tgaccctggt catcgtggtg tggagcgtgg ccgccctcat     1020

ctggccggtg cccatcatcg ccggcttcct gcccaacggc atggaacagc gccggaccac     1080

cgccagcacc accgcagcca cccccgccgc agtgcccgca gggaccaccg cagccgccgc     1140

cgccgccgcc gctgccgccg ccgccgcggc cgtcacttcg ggggtggcga ccaagtgacc     1200

cgctccgctc ctccctgtgt ccgtcctgtg tccgcgcgcg cgggtgcctt tcccgccgga     1260

gactcggccg gtgtgcttcg tgctgtagtt atcgttagtt cctcttcccg agatggggcc     1320

gccgagagac cccagcgcct ttgaaaagca aggtttgtgc tgcgcttcca gttccgaaaa     1380

gcagatgttt aagcccttgg actgagggtg ggatcgcagc tccgaagacg gagaggaggg     1440

aaatggggcc ctttcccctc tattgcatcc ccctgcccga ctccttcccc gcacccacgt     1500

gccctagatt catggcagaa aatgaccaaa tcctgtgtat ttgttttata tatttaataa     1560

ctgttttaaa tgaaagtttt agtaaaaaaa atacaaaaca aaaagattaa attgctattg     1620

ctgtagtaag agaagctctt tgtatctgaa catagttgta tttgaaattt gtggtttttt     1680

aatttattta aaattggggg gagggcatgg gaaggattta acaccgatat attgttaccg     1740

ctgaaaatga actttatgaa ccttttccaa gttgatctat ccagtgacgt ggcctggtgg     1800

gcgtttcttc ttgtacttat gtggtttttt ggcttttaat acagacattt tcctccagaa     1860

aaaaaaaaaa aaaaaa                                                     1876


<210>  1942
<211>  1901
<212>  DNA
<213>  homo sapiens

<400>  1942
cgcacttctg actcgagtcc ccgccgcgct tgtcgtcgcc gccgccggga tccgcagccc       60

cgcgccatgg agccggccgc gggcatccag cgccgcagct cccaggggcc caccgtcccg      120

ccgccgcccc ggggccacgc gccaccggct gccgcccccg gcccggcccc gctgagctcc      180

ccggtgcgcg agccgcccca gctggaggag gagcggcagg tgcggatcag cgagagcggc      240

cagttcagcg acgggctgga ggaccgaggc ttactagaaa gcagcacccg cctgaaacct      300

cacgaagccc agaactacag gaagaaggca ttgtgggtgt cctggttctc catcattgtc      360

accctggccc tcgcggtggc tgcctttact gtctccgtta tgaggtacag cgcctctgct      420

tttgggtttg catttgatgc catcctggac gtcctgtcat cggcgattgt cctgtggcgt      480

tacagcaacg cggccgctgt gcactctgcc catagggagt acatagcctg tgtcatcttg      540

ggggtgatat tccttctgtc atccatatgt atagtggtca aagccatcca tgacctctca      600

actaggctgc tcccagaagt ggacgatttc ctgttcagtg tctccatttt aagtgggatt      660

ctttgcagca tcctggccgt gttgaagttc atgctgggga aggttctgac cagtagagca      720

ctcataacag atgggtttaa ctccctcgtg ggtggcgtga tgggcttctc cattcttctg      780

agcgcggaag tgttcaagca tgactcggcg gtctggtacc tggacggcag cataggcgtt      840

ctgatcggcc tcaccatatt tgcctatggg gtcaaactcc tcatcgacat ggtgccgagg      900

gtgaggcaga cacgtcacta cgagatgttt gagtgaaggg ggccagcatc cgcatgagac      960

catcgagatg aggagtttcc acataggcaa agggtgccaa tatttaactg aacatctggt     1020

ttctttttgg aagttttctt tcacatggtt tgtcattaca agacaaggtc tgcccagcca     1080

ggtggatcta ccttgccccc atcacctgcc gcccccatca aacatgttgg gacaatgccc     1140

ataggaatgg acctccttcc ccgtctccag ctgggactgg cgttttttag tctctggagt     1200

atgatggttc tcatgggtag gatgagatct ttggcagaaa ggtcttcggt ggtgctctga     1260

gcctgcgctg cataggactg agcagaccca cctcctccag cttgggtggc cctgccactc     1320

ctggttccaa gtctctcctt tcctggcagg tcttaaggga agattgtacc cctcaccctt     1380

tacataccca gaatcatcag tatgtcactt cctaatttct atcagtgtat ctcattattt     1440

catactgttt tactaatcct aagtctaaac agatttgctc aaaaggagac cattctattt     1500

tttaaagtac ttagtgatac acgtataagc tttgcatgga cgaattaaat aagcacattg     1560

accttttctt gtacattcag aacctgaaca tccatgtgaa aactgggtcc atttttgaga     1620

gatgtgaaac tacagtttat ttgtaataaa taaatataat ctatccgtat atgcatatat     1680

ctatatgctg tgttaagtgg taatgggtac attacagtct gtgagagatg gatcgctccc     1740

tctgtaagga acaagacgtt ctcagctgat gtcacggtag gtttagattc tgtagagtgt     1800

tccccaaccc gcaccgttct gtacctctca caccactgct tgcccgggca gtagtggctg     1860

accaataaag acctttacct gttttgtatg gcaaaaaaaa a                         1901


<210>  1943
<211>  9443
<212>  DNA
<213>  homo sapiens

<400>  1943
gggcttggct tggagggggc aagggaggga aagagagaag ggggaaacac aaaaaacttc       60

tttctttctc cctccgttta tcttcagccc gacattgtca cctcctcttt gaggggttag      120

aagaagctga gatctcccga cagagctgga aatgcattgc actttgacta tggaaacaga      180

ggctattgat ggctatataa cgtgtgacaa tgagctttca cccgaaaggg agcactccaa      240

tatggcaatt gacctcacct caagcacacc caatggacag catgcctcac caagtcacat      300

gacaagcaca aattcagtaa agctagaaat gcagagtgat gaagagtgtg acaggaaacc      360

cctgagccgt gaagatgaga tcaggggcca tgatgagggt agcagcctag aagaacccct      420

aattgagagc agcgaggtgg ctgacaacag gaaagtccag gagcttcaag gcgagggagg      480

aatccggctt ccgaatggta aactgaaatg tgacgtctgt ggcatggttt gcattgggcc      540

caatgtgctt atggtacata aaaggagtca cactggtgaa cgccccttcc actgtaacca      600

gtgtggagct tcttttactc agaagggcaa ccttctgaga cacataaagt tacactctgg      660

agagaagccg ttcaaatgtc ctttctgtag ctacgcctgt agaagaaggg acgccctcac      720

aggacacctc aggacccatt ctgtgggtaa acctcacaag tgcaactact gtggacgaag      780

ctacaagcag cgcagttcac tggaggagca caaggaacgc tgccacaact atctccagaa      840

tgtcagcatg gaggctgctg ggcaggtcat gagtcaccat gtacctccta tggaagattg      900

taaggaacaa gagcctatta tggacaacaa tatttctctg gtgccttttg agagacctgc      960

tgtcatagag aagctcacgg ggaatatggg aaaacgtaaa agctccactc cacaaaagtt     1020

tgtgggggaa aagctcatgc gattcagcta cccagatatt cactttgata tgaacttaac     1080

atatgagaag gaggctgagc tgatgcagtc tcatatgatg gaccaagcca tcaacaatgc     1140

aatcacctac cttggagctg aggcccttca ccctctgatg cagcacccgc caagcacaat     1200

cgctgaagtg gccccagtta taagctcagc ttattctcag gtctatcatc caaataggat     1260

agaaagaccc attagcaggg aaactgctga tagtcatgaa aacaacatgg atggccccat     1320

ctctctcatc agaccaaaga gtcgacccca ggaaagagag gcctctccca gcaatagctg     1380

cctggattcc actgactcag aaagcagcca tgatgaccac cagtcctacc aaggacaccc     1440

tgccttaaat cccaagagga aacaaagccc agcttacatg aaggaggatg tcaaagcttt     1500

ggatactacc aaggctccta agggctctct gaaggacatc tacaaggtct tcaatggaga     1560

aggagaacag attagggcct tcaagtgtga gcactgccga gtccttttcc tagaccatgt     1620

catgtacacc attcacatgg gttgccatgg ctaccgggac ccactggaat gcaacatctg     1680

tggctacaga agccaggacc gttatgagtt ttcatcacac attgttcgag gggagcacac     1740

attccactag gccttttcat tccaaagggg acccctatga agtaaagaac tgcacatgaa     1800

gaaatactgc acttacaatc ccacctttcc tcaaatgttg acataccttt tatttttttt     1860

aatattatta ctgttgataa ttcttatttt gtggaggcag tgtcatttgc tctgcctaat     1920

tacgataagg aagaaacaga agagagaagg ggcgggaata ttgtttcttt atcacctggc     1980

ttgtttattt tgtgggaatt taagagcagt ccatttctac caaggcatat catgctttga     2040

aaaatcactt gattcataaa gattcaccta agagattctg atttgccact gatattcaga     2100

attatgatgg aagacaggaa agttcagagt tttctgggta ggactttggt ggtttaaaaa     2160

tggtataagt aactttattc ttgaaagaag aatgtgtttc aaactgtaaa ccaatttttt     2220

gttcttcaga gatcatggaa cacaaacaca ttgttatttt cagtgataac tcctaagagg     2280

agctgagttg ttgtgggttc tatgtttact tcccctatgg aatttataat tcagtatgtt     2340

ttacactgta ccatatagca aaacttttaa actacaggta gttaagggcc acctacaata     2400

catctgaggt cctgtgatct tatttttcta aacgtaagca ctgtttttcc atagttttga     2460

tgactggcat tttatagaca ccctggcagc cttactttta acacctttaa ggaatagtat     2520

ttttatgtag ttttcagaat aacatatggt ctaagagtgg ataaaaggca gtcaataatt     2580

tctgggaggg acttctactt tcataaattt gtttgagagg ttttctttta aagttgtaat     2640

gtgatggcag catagtatat gtatttgttt ctaaaagtat gcttacgatt gtcactttat     2700

cagcatttaa tcagtgttaa ccagtcagca gaaaaatata attatgctaa cagtaggggg     2760

agaaaaccca cttagaaatc ccttttctgg tatttctctt ttcactagtt tttttcaaga     2820

tgtgacctcc cggtgttctg tccatagttc attcatcctt tactcttcga gtagaaggtc     2880

ttaaaagtct tcctgtcggc tgtttctttc aaaatctcct cagagcaatt gctaatttgg     2940

cctgaatctg gtaacttgaa ccctgtaagg ttacagaact agggctattt attttagcat     3000

ttcttcagta gtatttacta ctcttgttgc aaagaaaagg gaatgggact tctttgtaac     3060

ctgtaccttg gacaacagat aaaagaaaca aaaaaataag aaagtttact tttacccttc     3120

ttggagtcta gaatgtgaca gaacccccaa aggaaagtcc tgcacatttt tctgtttcca     3180

aaacatttaa ttgtgtaagt ccttgtcaga aatgaatctc aatcccttag tatagaattc     3240

cccttacatg gtataggttg ccatatttca tgtgcagatt ttaatttcat ttatgtgggc     3300

gctctgtttt ttctttgcag tccagccaca ttagagggga ggaaccgagt gatattgatt     3360

caagtcattt tagggggaca tacttggaag gcagaacttg ctgcttctgt ttggggagga     3420

cagacctgac tgtgactgga ttatctgata accatttgtg aatactgaaa ttctgttagg     3480

cagtaactga taactgctct aaaggatcat taaataggat gctgaaatta tgtatcttaa     3540

tacagtgtgg tatgagaatt accaagtcaa gagaattgtg gacataagca agtttggccc     3600

caatactgct cttaactcat tttccagctt actatttgct atttaaatgg taggcaccag     3660

ctaagcactt ctaagcacta acacagctag aactaggcaa aaatggttag aactcagctc     3720

tcttctacta gtccctgtca taattatttt tgggaaaatg tccaaactgc cccctttaaa     3780

tctaagggaa tgcaccaaaa cagagatata tagaatgtca accatttcat tttttttttt     3840

ctgcatgcct tggtacatag tgaacataca acctatttaa agataaagca tgtttttgag     3900

actcgctcac ccccccccac ccaaccactc ccaaataata attgggatgc catttttttt     3960

ccttttggat gaggtaaata attttaaggt tcacaatttt gtcttttact gcaatttaag     4020

gaaacatttg gatgtcagtc aatatgttca taattttggc tgtgtgcgaa tttctgctgg     4080

cattatctat gaattttctt cctacttatt tttttttcag tatatgaaca atcatgtatc     4140

tacctgcccc aggatgaaac taaatttagg tggaccctaa accttatgaa gacagtgctg     4200

aggcactttc cttttctgat ttcatctttt tgggaatctg ttttattgaa ggtagttagt     4260

agttgagagt gcatttgcta caagcatata cttgtatctt cctagcttca tgaggaacag     4320

aaagaggtgg atatggctca gggtgtggca gggacaattg aggacaaagt caattcaaat     4380

ttgtgggtca gaaagaattt ttgtggacgt agtgtttttg gagaaactct ggatggttat     4440

atgtgcatgc cttttcttca aaaggaaata cgcaaggttg tagcatctaa aaataaacat     4500

aagagtcaga caccaaataa atcaagtttt acataacagt tgtatgccca gtttgtttag     4560

gtgagatttc acattacaga aagtatttga ggagcatgaa aatgggttat cttctgtatt     4620

ttccagtttg gcaaaagttc agaatttcat cacattgctt tgccctaatt ttgcccagaa     4680

ttttatctta gcctctctct gacagtgatg aatcatgctc aaaagccatt ctaattggac     4740

ctttttaaga cagggaaagg gatcagtagg cggattggaa gaaatttcaa gtcattgaaa     4800

tattccattg agatttccta aagggacaaa attgggaaaa taagaaacta cgacttagat     4860

ttggctacgt agtagaaagt atctccccta catacataca ggcaattgta tgtatgaatc     4920

atagggtata tgtgtgtgta tactacacac acattctttt aaagagaatt catggaaaaa     4980

aaagcagttg gagtgatcag atgtattgca aaaacataca gagaatttaa atgacagtta     5040

ataccaagaa attagttggg tttactttat caggtcgtaa taggaatcac taaagaagtt     5100

actagtgtgt ctttaggacc agtggcaact cttaaactaa aactttgggt ccttattatc     5160

tacttacaga acaaagtgaa acaaacaatg attaagctga ttggatatac attcaaagat     5220

atttaatgta aagttttttg gaatacgaag aaaattcaga aaataaatat tatcaacagt     5280

tacttattgg caaatagaga aagacaagaa tagtttagtg agcccggtat tttgttttta     5340

tagtttttat ctcagttgta caactcacaa aaccatgaag tctttggtat tttataaatg     5400

tttaacaaaa tttacatcag attaaggcat ttagatgaaa attattatgt tctcactatc     5460

ttccaaattt tatttcatcc tatctccaaa atgatttctt agggtacaaa aagagcagac     5520

ggggctgtaa aaatacaagc aaaaaactgt gtgcccctag tttcaggcag aacttaaact     5580

gtcagaggta ctagctacat gatttgtttt ttaactttgg attgttcacg tccaaaaatg     5640

gataaattac atttgtgttt atcatcagtt gcattttatg tattatttta ataaatacta     5700

tctgaatgaa gactattcta aaccagaaaa ttccccaaat ccaaaagaaa aaaaaagtgg     5760

gaagaggtga aattgaagtt tgtgtatatg aaagttatct tagacatatt tttaattctc     5820

cagtttctgc aaaataatta aaatatacag taactggtct cctaaatcct gaatttaatg     5880

tattaaatac ttatgttctt tatattggtg cctttttaaa atgcattgag agtgttggtt     5940

agctgttgca gctgtacaac acttttaata tgcattttta aaaatcactt aaaattgagt     6000

actatataat tcatctctgc atttttagtg caaatcttta gagcaatttc taatagagaa     6060

attttcagct cagctgttaa aaggaaaagg aaactttgaa actagacttt actacctttt     6120

tagtttcata gtatttctga atatgattac aagattatgc aggtaaaata tagagtgaaa     6180

ctttacctgt gaattgaatt ataatttgtg tttttgtttt gtttttaagg aagaataagt     6240

tctgtatcaa acaagaattt attagataat tttttggtca ataaaataca gtattcattt     6300

ggattttcat ctccagacta gtattgttct agtcttggaa tctgtatttt ctaatctgtt     6360

agaaaataga gattgaaaat tgatggaata atgtgaaaaa gcaggtaatt aattctcctt     6420

gaacaaagca aaactgaaca gtcatatcac attgctattc tccaaagcat aatctcaaat     6480

ggtttcatat catggttgtg tattacttgc aatgggtgtg ttaggatatg acagcttttt     6540

aaaaaaatga gctgctggtt atacaaagca aatggcatat gaccaagaag ctgtgatatg     6600

ctagtgtttc tttttatcat agtgtattac taggccaaat aatgacacct tgaatatttt     6660

tacatttatt gcagaaacct taaactttgg aatttccata aggtttttat gtaatattct     6720

atttctagct ttttagtttt atcttgctgt actgtaagtt tgaggatatt tttcacctgc     6780

actcttagga ataagttcat aattctgttt atggggcttt cctcccataa cactgcattt     6840

gtatattttc tgtataaaat atgtgttgtg tattaacctt tatcccatac agagagtggt     6900

acatgaatga ctagttttct aagatgtcct ttttattgtg aataaaatat aaaagttaaa     6960

ggccctctgc taagtcacat aaagtacagc atataagttc atataggtac aaataaatga     7020

gtttgcagtg aattgggcct tcaaattacc tcaagtgaca gatagtaaga aaagcttctt     7080

gagcaggtgg aggtcactga atcccctact atgcacttac caagatttta cttactttaa     7140

tttactggaa attgattttt taaaaaatga ctacactgta acaagggaag ggatctgggt     7200

ttttttgttg ttttattctt gtttttttta agtagttcaa attctgaaac tgtgatttaa     7260

aaatttttta cagtcaagca ttctgatttt gaacataact cccttccctt tctgtgtaac     7320

aaaggtctct ctgttatctc ttaaattttg ttacatctcc ctcagcctct ttctttgtcc     7380

gtctcccttc tgtcattgtc tatggatgtt tacctctctg ttctcctaaa agtttgaaga     7440

ttaggtcaac tcttatttct agttcattgg taatttaatc ttaatttttt tttcgtgatt     7500

tttgttggtt gtataatctg ctgacgtatt tttatactca agtgtagttt tctattaaaa     7560

agaaaagtgg ttggattaaa aatagtaagc tatgtaaccc tcatgttact ttcactttca     7620

aatattgggt acctaaaaca ttacttcaga gattatgtaa tcctattata gtatgtttgc     7680

tttcctttat tgttggattt tacattctga tttggctttc ctccaaaaaa tgtatatcat     7740

gaaagactag acagttattt gcaagtgttt agaaaggtgt taaaaatgta aagcaaagag     7800

tcttaacttt ctcctaattg ggagaaaaat gctttaacat tactataata atattccagg     7860

tttggagggg gtctccaggc cccatatttg ctgttaatag ttggaccttt tagaccatgt     7920

gttatttgca atcccagaat gattgcttct gctattagtt aaaaagatac tattcttttc     7980

tttctgtaca agtgcaatac tccccttgaa gtcttaaaaa ctatggtgat ttttttttct     8040

tttctgacct attcttcctt tagctaatga caaaaagaaa ctcataaaag tcatagtatg     8100

ttaaaggaca caacaagcaa agagaaaaac actccacaat caaaagatta cagaatgtgg     8160

aaaccactag tctgatctca tggtatcttt atttaagcta aatttccatg gaaattagta     8220

atcttttgct tgaaaaatgt gtcctaaagt tgaacttttt acagattgaa tcttcttaga     8280

ccctcgccca atgctctaaa ttaagaacct aatacttaat atttttattt tacttctccc     8340

cttttagaaa taaactttta aataaaagca aagcacttag ctgagtttta aacacttaca     8400

tatcacctat tggagaaatt ttttttaaaa atatttggag cagtcctgtt ttcatacaaa     8460

tttaagtaag aggtattttt cttatacata tttatatgta gtgtgctaat tttctttttt     8520

tatacctgtg tccctgtagt aaaactgctg taatataaat acatgttttg ttaaaagata     8580

acatttcttt ggcatttctt ttaaaggcag ttactgcatt tctgcatttg tacagtatgt     8640

gtcttggcca ttttagatat tctttcttta acaataccaa aggtaattag actattttaa     8700

agactaattg cttgacagtt tctagggtat tttgtgtttt agaagcaaaa aaagaaaaaa     8760

aaataggtca aaccagtaaa cctcattttt tttcaaacta ataatttggg gaaataaaaa     8820

ctattgttta aaaaagaaat atatatatat atatataaat atatatgtaa agttaaaatt     8880

ccataccttg tatgtcaggt ttgctaagtg taatgtagtt tttttaaggc tcaaatacca     8940

tacctcagaa aatgaggttt actatggaaa tactgaaaca gtctttgcag ctgtgtgaca     9000

agtcactcta ctacatactg atttggagac ctccgctaaa tagttttatc actgcagact     9060

aaaatgtggg acttgtatct tctttgtttt taatgcacac acatacatgt tctgtgcatg     9120

tatgtggtta ctgtgtatat gtgtatgagt gttgtatatg catgtgtgag tgtgtgtctg     9180

tatgtgtgta caactaaaga agctgcagaa actttgtaat actttgtgaa aaggattata     9240

ttataaaggt ttgtactgtc tgagtgcaca gctactggaa taaatttagg gaatctcagg     9300

aacaagcata taatttgtcc aagatttatt tcttctcaga agtgtaagtg cagtttttaa     9360

ttctgtatat tatttaatat tttaccaata aaataaactt ctgacataaa aagtttgcta     9420

taaaaaaaaa aaaaaaaaaa aaa                                             9443


<210>  1944
<211>  4161
<212>  DNA
<213>  homo sapiens

<400>  1944
gggagcgccg gggaggcggg cggaggcggg cggaggcggg gggcggggag cccgaggggt       60

ggaagccggc ggcggccgag cggggtcagt tctctgtagt gtttgccaat gttggagccg      120

tctgcaaagt gtccccggca agaagaggct gcctaccaca aggactttag cttacttttt      180

aaagattgaa gaaaaaaaag aagacagaaa aagaagaact caaagataca caaagtaatt      240

tgaaccaagg ctcagaagtt tttggagccg tgagggatac agcagtttgg tcaatattgt      300

cttaacatgc ttcaaataaa tcagatgttc tcagtgcagc tgagtcttgg tgagcagaca      360

tgggaatccg aaggcagcag tataaagaag gctcagcagg ctgttgccaa taaagctttg      420

actgaatcta cgcttcccaa accagttcag aagccaccca aaagtaatgt taacaataac      480

ccaggcagta taactccaac tgtggaactg aatgggcttg ctatgaaaag gggagagcct      540

gccatctaca ggccattaga tccaaagcca ttcccaaatt atagagctaa ttacaacttt      600

cggggcatgt acaatcagag gtatcattgc ccagtgccta agatctttta tgttcagctc      660

actgtaggaa ataatgaatt ttttggggaa ggaaagactc gacaagctgc tagacacaat      720

gctgcaatga aagccctcca agcactgcag aatgaaccta ttccagaaag atctcctcag      780

aatggtgaat caggaaagga tgtggatgat gacaaagatg caaataagtc tgagatcagc      840

ttagtgtttg aaattgctct gaagcgaaat atgcctgtca gttttgaggt tattaaagaa      900

agtggaccac cacatatgaa aagctttgtt actcgagtgt cagtaggaga gttctctgca      960

gaaggagaag gaaatagcaa aaaactctcc aagaagcgcg ctgcgaccac cgtcttacag     1020

gagcttaaaa aacttccacc tcttcctgtg gtggaaaagc caaaactatt ttttaaaaaa     1080

cgccctaaaa caatagtaaa ggccggacca gaatatggcc aagggatgaa ccctattagc     1140

cgcctggcgc aaattcaaca ggccaaaaag gaaaaggagc cggattatgt tttgctttca     1200

gaaagaggaa tgcctcgacg tcgagaattt gtgatgcagg tgaaggtagg caatgaagtt     1260

gctacaggaa caggacctaa taaaaagata gccaaaaaaa atgctgcaga agcaatgctg     1320

ttacaacttg gttataaagc atccactaat cttcaggatc aacttgagaa gacaggggaa     1380

aacaaaggat ggagtggtcc aaagcctggg tttcctgaac caacaaataa tactccaaaa     1440

ggaattcttc atttgtctcc tgatgtttat caagagatgg aagccagccg ccacaaagta     1500

atctctggca ctactctagg ctatttgtca cccaaagata tgaaccaacc ttcaagctct     1560

ttcttcagta tatctcccac atcgaatagt tcagctacaa ttgccaggga actccttatg     1620

aatggaacat cttctacagc tgaagccata ggtttaaaag gaagttctcc tactccccct     1680

tgttctccag tacaaccttc aaaacaactg gaatatttag caaggattca aggctttcag     1740

gtatgaatta aaagcaaaaa caaaaaacaa aacaattcat tagcctcaga ttcttcatct     1800

gtatacatca caaggctcat tcttgcctgc tagtatggcc tacatgccac ttacgtttta     1860

agttatttag gaacacaaag gacagacaaa aaagccatat gcacatgcct cattttctct     1920

tatttttgat ctatctagta attcttttgc tgcctgtctc ttctccattt tccttcttct     1980

tttttaagca tttttcatat tcttcactgt cttctatttg gtcttgatta ggtgcatcta     2040

tctcttcgct ctgtcttcca caaacaaaaa ttctgccttc agacatttgg tgttagtatt     2100

tcacactcag ttctcccttt ttttacataa ggattgagtt tctttttatg atgattttac     2160

ctttatagca attttgaatt ttgcattcta ttgctagtat tgattcaggt acaccattaa     2220

gatacaacat tctagaagtc tattacctta ggagttaatt aaacatgata tttgaagaat     2280

aatgaaatgc tttatagttg tttgaggcat aacaatgtgt atttgtttta ctggatcatg     2340

ttttgaactg actagggagg gtagcacctg cctcagatag taccaacaat tctgtttcac     2400

tgggtagtct aaaactagct tatagtttaa cttaacttgt tgtgtatgtg aatttaggga     2460

tggaaacttt ttttccccta tttattcttt gtttccttct gggaaaaaac cccacaaaaa     2520

tcagcactcc tttatggata cattggagct tttgaaagaa ttgtaaactc taggaagggg     2580

aaatatctgt gtcttgattt cttagttgcc ttgaaaatca tgtactgaac tgtaaccgct     2640

aacttgactg gatgaactag tttgcttgtg tgtagagagt gtattgcttc ctcagatttc     2700

actgttttca tctccttttc catcttagtc tttattcctt aagaccaaaa actgtaatat     2760

cctttagaaa tgctctagaa gatctgtatt gtgtagaatg atcatgtatt tataaatatt     2820

ttacaagttt agattataaa atgaaaaaga aggtcatgtg ttttgggggg tattttgcat     2880

gttcggattt ttttttcact tcaccgaacc cttctgattc tttcaaacta ttgccaggta     2940

gttgttagtg tttctaattg gactcttaat atgaacttca agaagctgtt accagttatc     3000

ggctctgtca tctgaaattt taaccactta atttaaagtt acaattttag aatttgtttt     3060

tgttgtttta ccttaagaaa cacaataaat cactgtttaa aaaagatctc aatttatata     3120

aagtactgga aaaaagctaa gtaattttta gttctatcta taatctccgt aggatgaatt     3180

agaaataaat tgtgatgaaa agaaattaac tgcttattta tgaatctaat catttagaaa     3240

tgtctgagag taacactgca ttcttataga aacaaagcac aaattgcatt caagctctga     3300

attgattttt tgcttggagc tgttgttaca gtagctgtaa ttttgctacc agaatgtctt     3360

aattttttaa atttgttttt atttctaagc tcttggcaat gacaataatt ataattttaa     3420

catatcttca ctgtagtcaa catgtagagt ctgcttccct cattattgca ttgctaaggc     3480

ctttttaaaa agcttatgct tacataatat actctttttt atggacacgt tatatgtttc     3540

caaatctgtg tattgtgatt tttacatact aatgaatata aacaggtgat tttaaaatat     3600

tactgtgctt ctttggttga atgagctggt attgatgtaa aatactctgt cattgatgga     3660

ccactacctg cagctaagca gtgagcagaa tctccgggaa atgacttagt ctggccacat     3720

gcatagccca tcttcataat gtcgcagcag aaggttcttt gtggttaaaa gttttaaagc     3780

ctatttcttt ataggtaacc ctctcaggta tatttacctg gtagaaaaac atgtagattg     3840

tttctattac ttaaatgttt taattggact gtagtttaga aattacagga ccagcttgtt     3900

acagattata cactattctg ttacttttat ttctgaaact taaaaacaat aaattctttt     3960

tctgtgtttc taggttagaa cttttttatt ttattgcaca ctgaacagat actgttgctt     4020

attgaatatt gtgtaaaccc ttctttggct ttccttgccc attgcaattt gatttaagcc     4080

tactagagcc attgtatgtg acagctatat tgtattacaa agtaaaaata tatgagtgta     4140

ttgaaaacaa aaaaaaaaaa a                                               4161


<210>  1945
<211>  4144
<212>  DNA
<213>  homo sapiens

<400>  1945
ggttggttct gagaaggctt caaggaatag gcagacattt cagcaaggct gctgaggaag       60

gataggctgt ggaaattagg atgcagcact cctgcccggg tcccgcctcg gggtcgccag      120

gccctgaacc ccaacgccgg cattagtcgc gcctgcgcac ggccctgtgg agccgcggag      180

gcaagggacg gagaacgggg cggaggcgga gtcagggcgc ccgcgcgtgg gccccgcccc      240

cttatgtcgg gtataaagcc cctcccgctc acagtttccc tagtcctcga aggctcggaa      300

gcccgtcacc atgtcgtgcg agtcgtctat ggttctcggg tactgggata ttcgtgggct      360

ggcgcacgcc atccgcctgc tcctggagtt cacggatacc tcttatgagg agaaacggta      420

cacgtgcggg gaagctcctg actatgatcg aagccaatgg ctggatgtga aattcaagct      480

agacctggac tttcctaatc tgccctacct cctggatggg aagaacaaga tcacccagag      540

caatgccatc ttgcgctaca tcgctcgcaa gcacaacatg tgtggtgaga ctgaagaaga      600

aaagattcga gtggacatca tagagaacca agtaatggat ttccgcacac aactgataag      660

gctctgttac agctctgacc acgaaaaact gaagcctcag tacttggaag agctacctgg      720

acaactgaaa caattctcca tgtttctggg gaaattctca tggtttgccg gggaaaagct      780

cacctttgtg gattttctca cctatgatat cttggatcag aaccgtatat ttgaccccaa      840

gtgcctggat gagttcccaa acctgaaggc tttcatgtgc cgttttgagg ctttggagaa      900

aatcgctgcc tacttacagt ctgatcagtt ctgcaagatg cccatcaaca acaagatggc      960

ccagtggggc aacaagcctg tatgctgagc aggaggcaga cttgcagagc ttgttttgtt     1020

tcatcctgtc cgtaaggggt cagcgctctt gctttgctct tttcaatgaa tagcacttat     1080

gttactggtg tccagctgag tttctcttgg gtataaaggc taaaagggaa aaaggatatg     1140

tggagaatca tcaagatatg aattgaatcg ctgcgatact ggcatttccc tactccccaa     1200

ctgagttcaa gggctgtagg ttcatgccca agccctgaga gtgggtacta gaaaaaacga     1260

gattgcacag ttggagagag caggtgtgtt aaatgggact ggagtccctg tgaagactgg     1320

gtgaggataa cacaagtaaa actgtggtac tgatggactt aaccggagtt cggaaaccgt     1380

cctgtgtaca catgggagtt tagtgtgata aaggcagtat ttcagactgg tgggctagcc     1440

aatagagttg ggacaattgc ttactcatta aaaataatag agccccactt gacactattc     1500

actaaaatta atctggaatt taaggcccaa cattaaacac aaagctgttg aaatattgat     1560

gaaaatgtaa gaatttttgt gaccacgggg taggagaagt ttctttaaag acgtaaaaag     1620

aaaaaaacca taggctgctc tgcctgtgga gtagccattc tttattcttt tactttttaa     1680

aataataaca atcacaaagg aaagatttgc caattgaata ggatcaaatt ctacaacttt     1740

tcctaaggca cccacaaata aatgacaagt gagacaaaaa gcactagtat aaagattata     1800

taaagaccta taaatcatta agacaactga gtttttaaaa atggacaaaa tccatgaaca     1860

atttataaaa tagaaatata gccaaaaatg tctaaaagat gtttatgatg taaggaatta     1920

tcaattacaa cagtgagaaa ccatatttcc ttctatccga tgagtaaaaa gtttctaaag     1980

tgttggcaag gcttaggaaa gtgatatgca tttcctgctg gtcaagttgt aaattagtat     2040

agctactttg gaggacaatt gtaaaattta aatcatatcc tatgacccag caattccatg     2100

ctataaaaac tcatccatgg ccgggcttgg tggctcacgc ctgtaatccc agcactttgg     2160

gaggctgagg tgggcagatc acgaggtcaa gagatcgaga ccatcctggc caacatgatg     2220

aaaccccgtt tctactaaaa atacaaaaat tagctgggca tggtggcatg tgcctatagt     2280

cccagctact caggaggctg aggcaggaga attgcttgaa cctgggaggc agaggttgca     2340

gtgagccgag atcacgccac tgcactccag cctggctaca gggcgagact ctgtctcaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaacattc aaagagacat atactaagat gttcactgtg     2460

gcattgtctg taatgacaaa taagtggaaa ccgtgtaaat acctgtcaat actatggagt     2520

accatgtggc aacggaagaa tgagactgaa ctgtgtgaac taacatgcaa agatccccaa     2580

aacaggccag gtgtggttgc tcacagctgt aataacaaca ccttcagagg ctgaggtgag     2640

aggatcagtt gaggccagga gtttaagacc agcctgggca acatagtgag acccctgtct     2700

cccaaaaatt ttttttaatt agctgtgcgc aattgctcat gcatagtccc agctacccag     2760

gaggctgagg tgggaggatc acttgagccc aggaatttga agctgcagtg agctgtgttc     2820

ttgccactgc actccaatct gggtgactga gcaagaccct gtctcttaaa aaaataaaaa     2880

agatctccaa gcatagagaa gagtctggag ggaaacacca aactcataac agtcttactg     2940

caggcaagtg ggataaaggc ccagactcca tggtggaagt taaagggcat ttccaagtta     3000

aggctaagac ttgcttttct aactaagaga atgtgctcat gcattgcttg tgtagtagaa     3060

actagttttt agaaaagaaa gcaaacttaa gaaacactga ctcctgtgga gatgacttgg     3120

caccactctc ctttcacaga gcagagtctg aatagtcttc agagataggc ctgtgggcca     3180

gattgccatc ccctatggac cagaagccaa ggatctctct agtgatggtc agagggccca     3240

aatggcaggg atacccagtg atgtcaggag gaatagtaca gacagaaggt gctaagcaga     3300

caattcaact gccatgtttt gccaccccct gtgagcaggg attaggtgtt caggccagta     3360

tcttgggcat gggggagcct ttggccagaa gaggtataaa gctcagaagt ttttcagtct     3420

gataactatt gatataattt ccatagtgtg agggagcggt atgctctacc cttgtgtatt     3480

taaggcagga cagagaaatt gaggatgccc ctggggctag atcgatgata tgaccagaaa     3540

tcaaaaaggg aatgcattat ttattgctgt gtaacactgt taagagagga ggtagttaag     3600

ggatggatag gcacatagag agggaaggtc tcaggagaag ggatagaaag gaactatgtt     3660

cacaagaaca acggcaagac agtgcctata ctgcctctac agttaatagg aaaaacggaa     3720

gaagttaccc ttaagctagg atgttgctca gaagtgacca tcccaacttt ggtgcgggca     3780

caataaatca gcctaaatgt ccctaattta acccagctca ttataatgtc attaaacatg     3840

acattagcat tgtggtttta gcacccccat gggttttgct taggcactca tgggtaataa     3900

ccaagatgga gtccctttgg caaaacttag gcatgcacag ctgtagtacc ccaagaagaa     3960

aatgttactt ctctcatctg ggcaaaaccc acagaagact tcccagcttc tgccacataa     4020

aagacacaga acacagacgc cttactggca acctgctttc aagacccctg tctttgctga     4080

gagctttcct ttttcccaat aaattctact ctgccctact cactctcaaa aaaaaaaaaa     4140

aaaa                                                                  4144


<210>  1946
<211>  4435
<212>  DNA
<213>  homo sapiens

<400>  1946
ggcgccgacc catgctggct gggaacgtgt ctcccggtga cgcagccccg ggtggggaac       60

gtggtgcggc ggcggcggcg gcggcgactg tacgcgcctc cgccgccccc gagaggacgc      120

gccgtgcagc ggctgagtgg cggcggcggc gacggcaaac ccggagctgc cggccggcgc      180

gcgggaggag gacgcgggtg cggtctagga agtaggtccc gggctccgcg ctcaacaaag      240

acggggccgc ccccattaga cggagctgcg ggcggaggct ccatgttggg aagcggcgcc      300

gttcgtgctt gttagcggga atccgggagc cgcggggtga gctggcgggg gccgggccct      360

aagtgaagat ggaggccccg ctgcggcctg ccgcggacat cctgaggcgg aacccgcagc      420

aggactacga actcgtccag agggtcggca gcggcaccta cggggacgtc tataaggcca      480

gaaatgtaca cacaggagag ctggctgcag taaaaatcat taaattggag cctggagatg      540

atttttcttt gattcaacaa gaaatattta tggttaaaga atgtaaacat tgtaacatcg      600

ttgcctactt tgggagttat cttagtcggg aaaaactatg gatttgtatg gaatactgtg      660

gtggcggatc acttcaagat atttaccatg ttactggacc attatcagaa ttgcaaatag      720

cctatgtatg cagagaaacc ttacagggtc ttgcctattt gcatactaaa ggcaaaatgc      780

atagagatat caaaggtgct aatattttat tgacagacca tggcgatgta aaattagctg      840

actttggtgt ggctgcaaaa ataacagcta ccattgcaaa acgaaaatct ttcattggca      900

ccccttactg gatggcccca gaagttgcag cagtagagaa gaatggtggc tacaaccaac      960

tctgtgatat ctgggcagta ggaataacag caattgaact tggagaactt cagccaccta     1020

tgtttgatct ccacccaatg agggctctct tcttaatgtc aaaaagtaat tttcagcctc     1080

caaaactaaa ggacaaaaca aaatggtcat caacattcca taattttgtc aaaatagcac     1140

taaccaaaaa cccaaaaaaa agaccaactg ctgaaagact tctgactcac acttttgttg     1200

cacagccagg tctctctaga gccctagcag ttgaactgtt agacaaagtg aacaatccag     1260

ataaccacgc acattacact gaagcagatg acgatgactt tgagccccat gcaatcattc     1320

gtcataccat tagatctaca aacaggaatg ccagagctga acggacagct tcagaaataa     1380

attttgacaa attacaattt gaacctcctc tgagaaaaga aacagaagca cgagatgaaa     1440

tgggattgtc atcagaccca aatttcatgt tacagtggaa tccttttgtt gatggtgcaa     1500

atactggcaa atcaacctca aaacgtgcaa taccacctcc cctacctcct aagccaagga     1560

taagcagtta ccctgaagac aactttccgg atgaagaaaa agcatcaacc ataaaacatt     1620

gtcctgattc agaaagcaga gctccccaaa ttctcagaag acagagtagc ccaagttgtg     1680

ggcctgtggc agagacttct tctattggaa atggtgatgg tatttcaaaa ctgatgagtg     1740

aaaatacaga aggatcagca caagcaccac agttaccacg aaaaaaggac aaacgagact     1800

tccctaaacc agccatcaat ggccttccac ccaccccaaa agttctgatg ggagcatgct     1860

tttcaaaagt ttttgatggc tgtcctttga aaattaattg tgcaacatcc tggatacatc     1920

ctgatacaaa agatcagtac attatttttg gaactgaaga tggtatttac acactgaatc     1980

tcaatgagct acatgaggca acgatggaac agttatttcc acggaagtgt acttggctgt     2040

atgttatcaa taatacttta atgtcattat cagaaggaaa aacctttcag ctctactctc     2100

acaatcttat agctttgttt gaacatgcca aaaaaccagg attagctgcc catattcaaa     2160

ctcacaggtt tccagaccga atactaccaa gaaaattcgc tttaacaaca aagattcctg     2220

atacaaaagg ctgccacaaa tgttgcatag tcagaaaccc ttacacggga cataaatacc     2280

tctgtggagc tttacagtct ggaattgttt tacttcagtg gtatgagcca atgcagaaat     2340

tcatgttgat aaagcacttt gattttcctt tgccaagtcc tttgaatgtt tttgaaatgc     2400

tggtgatacc tgaacaggaa taccctatgg tctgtgtagc tattagcaaa ggcactgaat     2460

cgaatcaggt agttcagttt gagacaatca atttgaactc tgcatcttca tggtttacag     2520

aaattggtgc aggcagccag cagttagatt ccattcatgt aacacagttg gagagagata     2580

ccgttttagt gtgtttagac aaatttgtga aaattgtaaa tctacaagga aaattaaaat     2640

caagtaagaa actggcctct gagttaagtt ttgattttcg cattgaatct gtagtatgcc     2700

ttcaagacag tgtgttggct ttctggaaac atgggatgca gggtaaaagc ttcaagtcag     2760

atgaggttac ccaggagatt tcagatgaaa caagagtttt ccgcttatta ggatcagaca     2820

gggttgtcgt tttggaaagt aggccaacag aaaatcctac tgcacacagc aatctctaca     2880

tcttggctgg acatgaaaat agttactaag caacagaaac tgatctcaaa tgacaggaaa     2940

atgaatatac tccattgaaa ggaaaaataa ggaaattcaa tacaaactgc actatgattt     3000

gctttaacta ttatgggtta tattgcaaat gatctgtact ttagggtaga attcaatatt     3060

ttctgcagct ggaaacagct agtctatctc ttgccactgt gtggtggtta tatcaagttt     3120

gcttaataaa agctatgaga caaatagtcc tctagttcca ggaaacacag tcttttttta     3180

aaaaaaacaa tgtttgtaac aagggtgcca tggtattttt agataactcg tgattatctt     3240

aagagaggta aatttagtga tcattttata tcatgtctta ttccttctta atgaacataa     3300

tttgttaaat tctcaagcaa ggttttcact tttatattgg ccattctgta tgtttttgta     3360

aaacagaata tttaatcctt atttattaat ctcttgctgg agtggtgtaa tgtatctaac     3420

ttttagcaaa ggagggttgc agagcagctt aaattttttt tataatgtat aagaattttg     3480

tttatctttt aagagtagta aagtactttg agtgtttggg ggttcaacac acacatgcaa     3540

ttttgcttaa caaaagtatt ttataataca gtttcataca gaattacctt aaaagggagt     3600

cttatgtttt caactacaga tagttgtaag ggatcataca gaagatattg atgatagttg     3660

aaatattctt agaaggggtg tgtatgtcta gctgtgtcta ccatgtgtat gtattcttga     3720

caagcagtat aaaatacctg tgatttttct ttacattagg gataatgcat aaggaattaa     3780

tcttcatata tattatcatc cctaatgtag cagggggaag tatttaattg cccatgatat     3840

gtattttact tatactatgc cagagaggaa actataaagt aattacacat gtaatcttgg     3900

gtttttcaca tatgtaggta ttcattttga gtaggttgaa gaagaaaaaa aatatttaaa     3960

tgaattgaat tcctgatggg atagtatcaa taagtattta aaagccagta ttctaaaaat     4020

aataaagggt agggtcattt ttgagtttgt ttttcttttg ctattgttaa tattcaaaat     4080

taaagtgtta cattggtacc tgttgtctta atgcatttat tgagaacagc attgagatga     4140

tgaacaaggg gttagcaata gcaaactcta taattatttt gactaattac ttaagaggaa     4200

aacagtataa gtatctcatt cagtatttag caattctgta aaataagtat tatctctatt     4260

tttcagatga ggaagtaagg gtttagcaag gttaagagat ctatccaatt tacacagcaa     4320

gttagtagtt gagcctgacc atgagtcttc tgactctgtt cttttcacta tgcaatacgc     4380

aaacaataaa atgttataca aatggaatat aaagttattt attctttaaa aatgc          4435


<210>  1947
<211>  4387
<212>  DNA
<213>  homo sapiens

<400>  1947
ggcgccgacc catgctggct gggaacgtgt ctcccggtga cgcagccccg ggtggggaac       60

gtggtgcggc ggcggcggcg gcggcgactg tacgcgcctc cgccgccccc gagaggacgc      120

gccgtgcagc ggctgagtgg cggcggcggc gacggcaaac ccggagctgc cggccggcgc      180

gcgggaggag gacgcgggtg cggtctagga aacggagctg cgggcggagg ctccatgttg      240

ggaagcggcg ccgttcgtgc ttgttagcgg gaatccggga gccgcggggt gagctggcgg      300

gggccgggcc ctaagtgaag atggaggccc cgctgcggcc tgccgcggac atcctgaggc      360

ggaacccgca gcaggactac gaactcgtcc agagggtcgg cagcggcacc tacggggacg      420

tctataaggc cagaaatgta cacacaggag agctggctgc agtaaaaatc attaaattgg      480

agcctggaga tgatttttct ttgattcaac aagaaatatt tatggttaaa gaatgtaaac      540

attgtaacat cgttgcctac tttgggagtt atcttagtcg ggaaaaacta tggatttgta      600

tggaatactg tggtggcgga tcacttcaag atatttacca tgttactgga ccattatcag      660

aattgcaaat agcctatgta tgcagagaaa ccttacaggg tcttgcctat ttgcatacta      720

aaggcaaaat gcatagagat atcaaaggtg ctaatatttt attgacagac catggcgatg      780

taaaattagc tgactttggt gtggctgcaa aaataacagc taccattgca aaacgaaaat      840

ctttcattgg caccccttac tggatggccc cagaagttgc agcagtagag aagaatggtg      900

gctacaacca actctgtgat atctgggcag taggaataac agcaattgaa cttggagaac      960

ttcagccacc tatgtttgat ctccacccaa tgagggctct cttcttaatg tcaaaaagta     1020

attttcagcc tccaaaacta aaggacaaaa caaaatggtc atcaacattc cataattttg     1080

tcaaaatagc actaaccaaa aacccaaaaa aaagaccaac tgctgaaaga cttctgactc     1140

acacttttgt tgcacagcca ggtctctcta gagccctagc agttgaactg ttagacaaag     1200

tgaacaatcc agataaccac gcacattaca ctgaagcaga tgacgatgac tttgagcccc     1260

atgcaatcat tcgtcatacc attagatcta caaacaggaa tgccagagct gaacggacag     1320

cttcagaaat aaattttgac aaattacaat ttgaacctcc tctgagaaaa gaaacagaag     1380

cacgagatga aatgggattg tcatcagacc caaatttcat gttacagtgg aatccttttg     1440

ttgatggtgc aaatactggc aaatcaacct caaaacgtgc aataccacct cccctacctc     1500

ctaagccaag gataagcagt taccctgaag acaactttcc ggatgaagaa aaagcatcaa     1560

ccataaaaca ttgtcctgat tcagaaagca gagctcccca aattctcaga agacagagta     1620

gcccaagttg tgggcctgtg gcagagactt cttctattgg aaatggtgat ggtatttcaa     1680

aactgatgag tgaaaataca gaaggatcag cacaagcacc acagttacca cgaaaaaagg     1740

acaaacgaga cttccctaaa ccagccatca atggccttcc acccacccca aaagttctga     1800

tgggagcatg cttttcaaaa gtttttgatg gctgtccttt gaaaattaat tgtgcaacat     1860

cctggataca tcctgataca aaagatcagt acattatttt tggaactgaa gatggtattt     1920

acacactgaa tctcaatgag ctacatgagg caacgatgga acagttattt ccacggaagt     1980

gtacttggct gtatgttatc aataatactt taatgtcatt atcagaagga aaaacctttc     2040

agctctactc tcacaatctt atagctttgt ttgaacatgc caaaaaacca ggattagctg     2100

cccatattca aactcacagg tttccagacc gaatactacc aagaaaattc gctttaacaa     2160

caaagattcc tgatacaaaa ggctgccaca aatgttgcat agtcagaaac ccttacacgg     2220

gacataaata cctctgtgga gctttacagt ctggaattgt tttacttcag tggtatgagc     2280

caatgcagaa attcatgttg ataaagcact ttgattttcc tttgccaagt cctttgaatg     2340

tttttgaaat gctggtgata cctgaacagg aataccctat ggtctgtgta gctattagca     2400

aaggcactga atcgaatcag gtagttcagt ttgagacaat caatttgaac tctgcatctt     2460

catggtttac agaaattggt gcaggcagcc agcagttaga ttccattcat gtaacacagt     2520

tggagagaga taccgtttta gtgtgtttag acaaatttgt gaaaattgta aatctacaag     2580

gaaaattaaa atcaagtaag aaactggcct ctgagttaag ttttgatttt cgcattgaat     2640

ctgtagtatg ccttcaagac agtgtgttgg ctttctggaa acatgggatg cagggtaaaa     2700

gcttcaagtc agatgaggtt acccaggaga tttcagatga aacaagagtt ttccgcttat     2760

taggatcaga cagggttgtc gttttggaaa gtaggccaac agaaaatcct actgcacaca     2820

gcaatctcta catcttggct ggacatgaaa atagttacta agcaacagaa actgatctca     2880

aatgacagga aaatgaatat actccattga aaggaaaaat aaggaaattc aatacaaact     2940

gcactatgat ttgctttaac tattatgggt tatattgcaa atgatctgta ctttagggta     3000

gaattcaata ttttctgcag ctggaaacag ctagtctatc tcttgccact gtgtggtggt     3060

tatatcaagt ttgcttaata aaagctatga gacaaatagt cctctagttc caggaaacac     3120

agtctttttt taaaaaaaac aatgtttgta acaagggtgc catggtattt ttagataact     3180

cgtgattatc ttaagagagg taaatttagt gatcatttta tatcatgtct tattccttct     3240

taatgaacat aatttgttaa attctcaagc aaggttttca cttttatatt ggccattctg     3300

tatgtttttg taaaacagaa tatttaatcc ttatttatta atctcttgct ggagtggtgt     3360

aatgtatcta acttttagca aaggagggtt gcagagcagc ttaaattttt tttataatgt     3420

ataagaattt tgtttatctt ttaagagtag taaagtactt tgagtgtttg ggggttcaac     3480

acacacatgc aattttgctt aacaaaagta ttttataata cagtttcata cagaattacc     3540

ttaaaaggga gtcttatgtt ttcaactaca gatagttgta agggatcata cagaagatat     3600

tgatgatagt tgaaatattc ttagaagggg tgtgtatgtc tagctgtgtc taccatgtgt     3660

atgtattctt gacaagcagt ataaaatacc tgtgattttt ctttacatta gggataatgc     3720

ataaggaatt aatcttcata tatattatca tccctaatgt agcaggggga agtatttaat     3780

tgcccatgat atgtatttta cttatactat gccagagagg aaactataaa gtaattacac     3840

atgtaatctt gggtttttca catatgtagg tattcatttt gagtaggttg aagaagaaaa     3900

aaaatattta aatgaattga attcctgatg ggatagtatc aataagtatt taaaagccag     3960

tattctaaaa ataataaagg gtagggtcat ttttgagttt gtttttcttt tgctattgtt     4020

aatattcaaa attaaagtgt tacattggta cctgttgtct taatgcattt attgagaaca     4080

gcattgagat gatgaacaag gggttagcaa tagcaaactc tataattatt ttgactaatt     4140

acttaagagg aaaacagtat aagtatctca ttcagtattt agcaattctg taaaataagt     4200

attatctcta tttttcagat gaggaagtaa gggtttagca aggttaagag atctatccaa     4260

tttacacagc aagttagtag ttgagcctga ccatgagtct tctgactctg ttcttttcac     4320

tatgcaatac gcaaacaata aaatgttata caaatggaat ataaagttat ttattcttta     4380

aaaatgc                                                               4387


<210>  1948
<211>  1187
<212>  DNA
<213>  homo sapiens

<400>  1948
gccctgcagg cgctgcggac aggggaagca cagagattcc ccgccgcgtt ccctggactc       60

aggagctcgc cgcgatgccc cgccccactc tccacccgct gaatgcaggg cgcatgctgc      120

tacttggcgg ctcaagcccc gcccgcaccg tccccattct ctgaccgccc ctctcccggt      180

acactgcgca ggcacaacag agccgctccc ctctcctcgc cccgccaccg ggacggagag      240

cgcccgccgc tgcatttccg gcgacacctc gcagtcattc ctgcggcttg cgcgcccttg      300

tagacagccg gggccttcgt gagaccggtg caggcctggg gtagtctcct gtctggacag      360

agaagagaaa aatgcaggac actggctcag tagtgccttt gcattggttt ggctttggct      420

acgcagcact ggttgcttct ggtgggatca ttggctatgt aaaagcaggc agcgtgccgt      480

ccctggctgc agggctgctc tttggcagtc tagccggcct gggtgcttac cagctgtctc      540

aggatccaag gaacgtttgg gttttcctag ctacatctgg taccttggct ggcattatgg      600

gaatgaggtt ctaccactct ggaaaattca tgcctgcagg tttaattgca ggtgccagtt      660

tgctgatggt cgccaaagtt ggagttagta tgttcaacag accccattag cagaagtcat      720

gttccagctt agactgatga agaattaaaa atctgcatct tccactattt tcaatatatt      780

aagagaaata agtgcagcat ttttgcatct gacattttac ctaaaaaaaa agacaccaaa      840

cttggcagag aggtggaaaa tcagtcatga ttacaaacct acagaggtgg cgagtatgta      900

acacaagagc ttaataagac cctcatagag cttgattctt gtatattgat gttgtctttt      960

ctttctgtat ctgtaggtaa atctcaaggg taaaatgtta ggtgtcagct ttcagggctc     1020

tgaaacccca ttccctgctc tgaggaacag tgtgaaaaaa agtcttttag gagatttaca     1080

atatctgttc ttttgctcat cttagaccac agactgactt tgaaattatg ttaagtgaaa     1140

tatcaatgaa aataaagttt actataaata ataaaaaaaa aaaaaaa                   1187


<210>  1949
<211>  1201
<212>  DNA
<213>  homo sapiens

<400>  1949
gccctgcagg cgctgcggac aggggaagca cagagattcc ccgccgcgtt ccctggactc       60

aggagctcgc cgcgatgccc cgccccactc tccacccgct gaatgcaggg cgcatgctgc      120

tacttggcgg ctcaagcccc gcccgcaccg tccccattct ctgaccgccc ctctcccggt      180

acactgcgca ggcacaacag agccgctccc ctctcctcgc cccgccaccg ggacggagag      240

cgcccgccgc tgcatttccg gcgacacctc gcagtcattc ctgcggcttg cgcgcccttg      300

tagacagccg gggccttcgt gagaccgctt gttttctgca ggtgcaggcc tggggtagtc      360

tcctgtctgg acagagaaga gaaaaatgca ggacactggc tcagtagtgc ctttgcattg      420

gtttggcttt ggctacgcag cactggttgc ttctggtggg atcattggct atgtaaaagc      480

aggcagcgtg ccgtccctgg ctgcagggct gctctttggc agtctagccg gcctgggtgc      540

ttaccagctg tctcaggatc caaggaacgt ttgggttttc ctagctacat ctggtacctt      600

ggctggcatt atgggaatga ggttctacca ctctggaaaa ttcatgcctg caggtttaat      660

tgcaggtgcc agtttgctga tggtcgccaa agttggagtt agtatgttca acagacccca      720

ttagcagaag tcatgttcca gcttagactg atgaagaatt aaaaatctgc atcttccact      780

attttcaata tattaagaga aataagtgca gcatttttgc atctgacatt ttacctaaaa      840

aaaaagacac caaacttggc agagaggtgg aaaatcagtc atgattacaa acctacagag      900

gtggcgagta tgtaacacaa gagcttaata agaccctcat agagcttgat tcttgtatat      960

tgatgttgtc ttttctttct gtatctgtag gtaaatctca agggtaaaat gttaggtgtc     1020

agctttcagg gctctgaaac cccattccct gctctgagga acagtgtgaa aaaaagtctt     1080

ttaggagatt tacaatatct gttcttttgc tcatcttaga ccacagactg actttgaaat     1140

tatgttaagt gaaatatcaa tgaaaataaa gtttactata aataataaaa aaaaaaaaaa     1200

a                                                                     1201


<210>  1950
<211>  1623
<212>  DNA
<213>  homo sapiens

<400>  1950
ggaggggcgc gcggccgcga gcaaaggagg gagggaagga aggaagagag ggaggcgggc       60

aagcaggcgg gcgcgggggt cggggactga ggcagtagag ggaggcgaga gcccggcagc      120

cgcttcgcgc tgtttgctgc gcgggctttt ggagggggcg gccgtttagt cggctgagga      180

gaagcggaca ccagcggcgt tggtgatagc gcctggggga gggggactgg agaggcgaga      240

aggggggtcg ctgcggtggt tctctcgctg tcgctctctc tttgcctcgc tcccggctcg      300

gcgggctcct cccggcgtct ctctcgcctc cggggtcccg ctccccgccc cccgcggtat      360

gtcttgatcc cgagcagcgg gtttcatggg gctcctcagg attatgatgc cgcccaagtt      420

gcagctgctg gcggtggtgg ccttcgcggt ggcgatgctc ttcttggaaa accagatcca      480

gaaactggag gagtcccgct cgaagctaga aagggctatt gcaagacacg aagtccgaga      540

aattgagcag cgacatacaa tggatggccc tcggcaagat gccactttag atgaggaaga      600

ggacatggtg atcatttata acagagttcc caaaacggca agcacttcat ttaccaatat      660

cgcctatgac ctgtgtgcaa agaataaata ccatgtcctt catatcaaca ctaccaaaaa      720

taatccagtg atgtcattgc aagatcaggt gcgctttgta aagaatataa cttcctggaa      780

agagatgaaa ccaggatttt atcatggaca cgtttcttac ttggattttg caaaatttgg      840

tgtgaagaag aaaccaattt acattaatgt cataagggat cctattgaga ggctagtttc      900

ttattattac tttctgagat ttggagatga ttatagacca gggttacgga gacgaaaaca      960

aggagacaaa aagacctttg atgaatgtgt agcagaaggt ggctcagact gtgctccaga     1020

gaagctctgg cttcaaatcc cgttcttctg tggccatagc tccgaatgct ggtaggggag     1080

ataaagttgg ctcagattga ttatcatcct tattatctct gtaatctgtg tttcatttca     1140

caagggctag atatagggaa atcggtgaaa gactagacta aaaataacat gtaattcagt     1200

aatatctagt tttgcagtta cttttaaatg catttaaaag attcctcatg tagagtgata     1260

tcctaatatc cttgcattgt tttctgagat gccggttttt agtatttctt atttttggtg     1320

ttatgttttg ctgtattcca gcagagctct tagagactgg gggtgggggt gggtgtcata     1380

aatcttattt tgtccaaagc ttactgtttt agctattcat gttaaattaa gaaaaggctt     1440

agtgggttaa aattcacctg gttttactgt taaactgatt ttgactttaa gagaagccaa     1500

ggttatggct gtggtttagt ttgctagtaa atatcaagtg gaaaataaag atactttaat     1560

aagaactgta tttcctcaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaa                                                                   1623


<210>  1951
<211>  6770
<212>  DNA
<213>  homo sapiens

<400>  1951
ggaggggcgc gcggccgcga gcaaaggagg gagggaagga aggaagagag ggaggcgggc       60

aagcaggcgg gcgcgggggt cggggactga ggcagtagag ggaggcgaga gcccggcagc      120

cgcttcgcgc tgtttgctgc gcgggctttt ggagggggcg gccgtttagt cggctgagga      180

gaagcggaca ccagcggcgt tggtgatagc gcctggggga gggggactgg agaggcgaga      240

aggggggtcg ctgcggtggt tctctcgctg tcgctctctc tttgcctcgc tcccggctcg      300

gcgggctcct cccggcgtct ctctcgcctc cggggtcccg ctccccgccc cccgcggtat      360

gtcttgatcc cgagcagcgg gtttcatggg gctcctcagg attatgatgc cgcccaagtt      420

gcagctgctg gcggtggtgg ccttcgcggt ggcgatgctc ttcttggaaa accagatcca      480

gaaactggag gagtcccgct cgaagctaga aagggctatt gcaagacacg aagtccgaga      540

aattgagcag cgacatacaa tggatggccc tcggcaagat gccactttag atgaggaaga      600

ggacatggtg atcatttata acagagttcc caaaacggca agcacttcat ttaccaatat      660

cgcctatgac ctgtgtgcaa agaataaata ccatgtcctt catatcaaca ctaccaaaaa      720

taatccagtg atgtcattgc aagatcaggt gcgctttgta aagaatataa cttcctggaa      780

agagatgaaa ccaggatttt atcatggaca cgtttcttac ttggattttg caaaatttgg      840

tgtgaagaag aaaccaattt acattaatgt cataagggat cctattgaga ggctagtttc      900

ttattattac tttctgagat ttggagatga ttatagacca gggttacgga gacgaaaaca      960

aggagacaaa aagacctttg atgaatgtgt agcagaaggt ggctcagact gtgctccaga     1020

gaagctctgg cttcaaatcc cgttcttctg tggccatagc tccgaatgct ggaatgtggg     1080

aagcaggtgg gctatggatc aagccaagta taacctaatt aatgaatatt ttctggtggg     1140

agttactgaa gaacttgaag attttatcat gttattggag gcagcattgc cccggttttt     1200

caggggtgct actgaactct atcgcacagg aaagaaatct catcttagga aaaccacaga     1260

gaagaaactc cccactaaac aaaccattgc aaaactacag caatctgata tttggaaaat     1320

ggagaatgag ttctatgaat ttgcactaga gcagttccaa ttcatcagag cccatgccgt     1380

tcgagaaaaa gatggagacc tctacatcct cgcacaaaac tttttctatg aaaagattta     1440

ccctaagtcg aactgagtat aaggtgtgac tattggattc ttgaactaaa atttgaccct     1500

gtcttcacct ttgttctcag ctccacagtc tggattgctg acagtaggtg tatatgacaa     1560

tttgtattga gccaaattag gaaacagaca gtaacgtcaa ggaagtagat actggctggc     1620

attgtcagtg ttctaagttt caggcatttt tatttttcct ggctaaacgt tggtgaaagt     1680

tataacctcc tgcctgggag aaaatataca tcacctaaaa tgaacttatg gcaggtctaa     1740

tcaaaaggct aaatacaatt tcagaaaagg ttctgatact cttgtttttg ataaagcatt     1800

ttttcaacta accatgaatt aagatgagtc catttgcctc ttctgccttc actgagggtt     1860

tgggttatac acctctactg aattgtgtta ataactgttt ggcagtgtgt actttgtttt     1920

tgtgagtcat gtctcatgaa atttattgga atgtttaatc atatttgcta agaaatgttt     1980

ctgctgtagt tggatttgcc catatttatg taggtggttt taatttttta aatggtgatt     2040

agtgttaaaa atcaatttaa atcatgacta atatggtaaa aagataaagc atcaaagcag     2100

tatttctcat tcctgcctcc tcaatatcta atactgggaa gatacttcaa agaatattga     2160

gattgtctga agttttagtt aagattttca cacattaata tcaaaaaagt aagtttagta     2220

tttgtttctc catgggttat ttgtaaagct gtaaactgag atatcggtga ctccgtatta     2280

tgactccatt agtgagctgt ggtatgggta ggattttcct acttcttctg tacttttacc     2340

tgtagactat ttttactaag gtgctttata atgtgtttta aagcattgca tttacaaaac     2400

aaggaaaatg ctgtaaatat tgcatatttt atgtatttgg accaaaaggt tacaagtaat     2460

tagacaaaag tggttttgca ccaattttat gtcaagtaaa accatcagac ctactgttct     2520

tgtatttctc atttaacttt actgttaaga catcactgaa atgaacttca gtaagctttc     2580

aattttgata cacagttcat tattcataac ttgaggcagt aattacagtg gaatgagtac     2640

tggacaagga gtcaaaaaac ttgatttcag gtcctagctc tagcacttac agctgtgtga     2700

tcttgggcaa gtcacttaac ctctctttgc ctcaatttcc tcatcttgaa atgaggataa     2760

taatacctgc tgtacctacc tcacagggct gttgtgagga ttaaatgaga tggcatgtga     2820

aagcactttg aaaattgtaa agcgctatgt aaatgtaagg tattatagaa acatctttaa     2880

catatagttt cataccattc attttttaac aaagaaaggg aaaagtctgc ttgtaagctg     2940

gttgaaaaag ttaatcttga tataaatttg tgtttgataa atatcctctc agtgttttat     3000

cttccatgtt tcaacaacta ttgaaatatg aaatgcctgt gaactcttaa agcttcatga     3060

gcagctgctt gagttcagga agttcactgt tagaaatagg ctttgttagc tgactagggt     3120

cagggaaact tttctcttca aatttgaaag ctgtttctgt tttcatttta cattattatt     3180

cagaaatggt agctattcta tacctatggt ttaagtaaat atttctgaat aaggcttcac     3240

catactgtaa gcattttagg tagattgcct taaaggttat gggagggcat gagggaacac     3300

ttcttatgag aaaacattta taaacaaaag aaacatttat aaactaaaga aaaactaaaa     3360

gaatgacaga acaatcatct tagcaccctt tcctcacaat aatataaaaa tattaaaaga     3420

acataggcag gcttttttta aatttggctt ttttctttcc ttttttcaaa ttgactttta     3480

taggtatttc ctgaaagtgt atacaaatta tttcctcgcc caaaataaag caccacttca     3540

aggtgtggtt tgacattaca tgctaatgaa caaacccagt atgcaagtta ttcttgcacc     3600

acatgctcaa atcttcttga ggtgcattaa ctcttttagg taactagagc agtacttggt     3660

gaactagatc aggaggtcag taaactttct gtggaagggc cagagagtaa atattttagg     3720

ctttgcagcc catacggtct ctgtcacagc tagtcaaccc tgccatttta ccacaaaagc     3780

agcaatagac attatgtaaa caaatgagca cagttatgtt ccaataaaac tttatttaca     3840

aaaacagatg acatcccaga tgcagaccat gggcaaccaa ccattgcact ggccaaatca     3900

ttatttatgg agaaatcctc tttgtgtctc tactctagat gcctaaaaga gtttatatac     3960

ttctaaaagc tcctaactta tatccaaaga attgctttct gattcgtgta gtctctccca     4020

cagattcata aacttttatg acttatattg tttccaggtg ggcatggttt atttcccagt     4080

ttaacagttc agaatagggg catttatttt atcatatttt agggtgggtt aggagtatcc     4140

tttctggaga ctgagaaagg ggtgtattta attccatcag gtccagtaca gtactaggag     4200

tcataatact ttataatcaa ttaaataaat agaaccactg agacaataat gtattttttt     4260

aaagtggcaa atgtggtttt cttttttcag cctttgcgct ttttcagtat tttgaccata     4320

gggagataat ttttttataa tacaaaagta accacttgga attttaaaga taatgttatg     4380

tgtgtatgtg aaatatatat acatatatat atatatgttt atttcctaaa agaagaaaag     4440

atacctttct gttcaacttg tatcaactcc tcttttctaa ttgctgtgaa atggcaactg     4500

ttgataaatt attgtgattg ttttaaaatc taatgggaag taaaatatat tttgatttta     4560

cccagcttaa tctgtaaagt agcacttaaa tatatctgat agcaacactt aagatattgc     4620

atggggatta ctttcctatc atccatatgc atttgtgcaa cttcaaacat attgggtgct     4680

tctgaattcc tgatgattgg atttaagcta ttgaaaattg gataatttaa acttaatgat     4740

ttttataatt ttctgatctt aaaatttggt taatgcctat aatctgttgc tttttctcaa     4800

tatgtgtcct attggaaatt cctcaaatcg ttggtgccat cagtgattta caaacaatat     4860

tttgatattg cagatgactt gcttactgta tttgcattgt tagaaaacag tttgtagaca     4920

atgattcttt tttaataaaa tcaaataatt ctaaaagtgc tagagaattt aactaaaagc     4980

tggttcccaa atgcatagct ggcattttaa tttaaattca aatctacata gagaacatct     5040

gtgtaaatca tctaactgga tttttccatt ggtcattccc aaacacacct atggtcctag     5100

aatccttaag agaagcaccc tgtaaccttt tatgtggttt gcctttaaga ggcccaggtg     5160

cttctccttt atgatttgag ttggcctctt cataaattag tgctgtttac tttcagagga     5220

agcagagaag ttgctgttat gtttttgcat ccgtttaccc tatgcaaagt tgctgtatga     5280

tgccaactaa actactcttt aggcagcctt ctgaggagaa aagcaaccct gtttcaaatc     5340

cactgccaat tcagctcctc tggagtggag ctttctgatt tcttggagca ggaattttag     5400

agattgaaat gaatgatcat ttagtcagat ttatcctgta atttcatgca gctttgtggc     5460

ctttgcagta ctatttataa aatggaccct gatggtgatg aactctttag aacgcattac     5520

tgttaagcct gtgttgagac attgatgctg tctatctcat tttttagaca gtttttgtag     5580

ctttctattg agagtcaggt atgtgagcat ctctgaagca gtgttgaatg taattttcgg     5640

aaacatggat tgtgtatttt gacttttatt ttataaatac acagctcaac agtgcctttt     5700

ttttccctca tagtcctgtt ggaagatgct cactactttc tctcttctct ctccctgccc     5760

tcccccactc cattcagttg attcatttat gcaaattctg tttccaactt gaaaccattt     5820

tgtcacatct gttggagaga taatcactcc ttttccttaa cattctgcca gctttctgat     5880

gttgaagtgt ttcagttgac tacctgatgc aaaagctata aaataaacag tgggaagggg     5940

aaaaattggt gtcctgtttt aatattttct tttgtagcct tgacactgat ggacattttc     6000

caagctgact cagtgttcag tgtcaactta actctcagat agtgttgcca tcaagaaagc     6060

atgcaacatc attggtttct aatgatttta tggcttgtga caatatttta tctggactga     6120

catgcctctg ctgcttttgc tttgtacttc attgctggta ataaaatttc agatggaaaa     6180

cttacaaaat atatacttaa ttagaagaaa aaaatagaga aagggctatt agaattaaaa     6240

aaatttgaaa gtaacttaat ctaacattta tggcacagtt tggacatatc cataattttt     6300

tttgggaaca cacatttctg attttttttt tcccccttaa agaagaaagt ctcaattcca     6360

ttgattttca attcttagcc actggctcat tgctttgagc aatgcttgat tgattctatt     6420

tatattatat gatattgggt tgataaaata ccagttcaat gatgagtttt cttaacagaa     6480

tttggtttgt acttgcagtg gctgaacaaa gagcatggct tgagaatcaa agggatctgc     6540

atttagcaat gtgatgtcag taaatggaca taacaggatt gttgtaaagg ttgggcatga     6600

tgtatgcaaa gtactggcca gggtagacta ataactgatg gcatttatat gctgtgctgg     6660

aatattgtta ccaagctgat gtgccgttct caccctgcag aatactggtt ttgtcatttc     6720

ataaatgata tttttataaa tatttttgaa tgactgtaaa aaaaaaaaaa                6770


<210>  1952
<211>  3966
<212>  DNA
<213>  homo sapiens

<400>  1952
gcgccccgcg cccgggcccc ggcgatggtg acacatgcgg cggcggcgcg ccggcggcag       60

gaccatggtt gagcgcgcca gcaagttcgt gctggtggtg gcgggctcgg tgtgcttcat      120

gctcatcttg taccagtacg cgggcccagg actgagcctg ggcgcgcccg gcggccgcgc      180

gccgcccgac gacctggacc tgttccccac acccgacccc cactacgaga agaagtacta      240

cttcccggtc cgcgagctgg agcgctcgct gcgcttcgac atgaagggcg acgacgtgat      300

cgtcttcctg cacatccaga agacgggcgg caccaccttc ggccgccacc tcgtgcagaa      360

cgtacgcctc gaggtgccgt gcgactgccg gcccggccag aagaagtgca cctgctaccg      420

gcccaaccgc cgcgagactt ggctcttctc ccgcttctcc accggctgga gctgcgggct      480

gcacgccgac tggaccgagc tcaccaactg cgtgcccggc gtgctggacc gccgcgactc      540

cgccgcgctg cgcacgccca ggaagttcta ctacatcacc ctgctacgag accccgtgtc      600

ccgctacctg agcgagtggc ggcatgtgca gaggggtgcc acgtggaaga cgtcgttgca      660

tatgtgtgat gggcgcacgc ccacgcctga ggagctgccg ccctgctacg agggcacgga      720

ctggtcgggc tgcacgctac aggagttcat ggactgcccg tacaacctgg ccaacaaccg      780

ccaggtgcgc atgctggccg acctgagcct ggtgggctgc tacaacctgt ccttcatccc      840

cgagggcaag cgggcccagc tgctgctcga gagcgccaag aagaacctgc ggggcatggc      900

cttcttcggc ctgaccgagt tccagcgcaa gacgcagtac ctgttcgagc ggacgttcaa      960

cctcaagttc atccggccct tcatgcagta caatagcacg cgggcgggcg gcgtggaggt     1020

ggatgaagac accatccggc gcatcgagga gctcaacgac ctggacatgc agctgtacga     1080

ctacgccaag gacctcttcc agcagcgcta ccagtacaag cggcagctgg agcgcaggga     1140

gcagcgcctg aggagccgcg aggagcgtct gctgcaccgg gccaaggagg cactgccgcg     1200

ggaggatgcc gacgagccgg gccgcgtgcc caccgaggac tacatgagcc acatcattga     1260

gaagtggtag tggcggtggt ggccacgggg aggcctcttg gggggtgtgg gggataaaac     1320

aggacagacg acaggtccac ccaagactgt caagggatga gcatcccaaa cctgctccac     1380

agaggtagct gcgtcctgaa aaaaaacaga gcagggatgt agtggggctg ggcagggatg     1440

ggggcttgag aaatcaacag gtgcagccca gtgggtcaga ggaaagcgtg ctcgaaggat     1500

gccatggtca gggcagggcc tccagagcag gtgttgtgcc tggagctgct ctcctggcct     1560

ccttggattt atcgcaaaaa ctgaaggttt gcgcaagaga cgaggacagc ggaaagtgga     1620

cctgccaggc cgggagtgtg tccctcacca actatgcaca cagcactcgc tcttagctcc     1680

tctgtccggg ctactaggag tgagaccagc ttctggcaac tgccccagct ccaggccatc     1740

ccatagcccc tcctcttctg gctgccccca atgccccgag gcctggggag cccccagctc     1800

acccatctgt agctccctca aagtcagggc ccaccccatc tgaggcagag aagactcgag     1860

tccagccccc aggaagcctg ctcccctctc tggcccatgg tcctgcttca tgctttgggt     1920

caggaggcca aagctgatgt tcaggcccca cccactccct acagtcctca gaccaaggag     1980

gggtttgggt agtaggcccg agctgcattg ccggccttcc tcgggccaac tggcagccca     2040

ggagtgggga ggctttggcc agggatgctg ccacttgtgc gtgagtccgc ggctggccct     2100

tggaggtgac catccaggca ggcctggctc agactggaag ggctggggac cgagggctcc     2160

cctgcctctg ttctcctttc tgacccactg ggatttgcta gcaggctgcc ccagccccat     2220

caccgaaaca catactcaag agctcaaata ccactgctcc caccagcgta cggattaagt     2280

tcatcaggct tccatcggct ggagcatggg accatagccc ctgcccagga gccgtaccct     2340

cggaccacag tggctctgta tggccaggaa ctgggactcg agctttcaga ttctcaacta     2400

gccttggcaa aacagctgta ggtggcctcc ctgacaacag acactcagcc ctccccaccc     2460

tggctctcct tgcatttccc catgctcccc accccctggc aaaaggctgg ccatgctctg     2520

ttcccagcag ccgcgcaggt ttccccactg gctgcaatgg ccctaccaaa agccatgttg     2580

catatccgtt gtaagcacgt gccctgtgcc ctgtccccat tccttatgcc ctaggaggcc     2640

aagctggtgt ctctaggagg gcccacacag gcaccctgga tcccccagag agtagattgg     2700

tgtgctcagg ccgcaggctg actcagaggt agggcagtgg gctctgcagg ccacctggct     2760

ggggttggtg ggggtcctct ctcctgcccc agcttccact cagccaccac agttgccaca     2820

ccatggggtg gagacgtggg tcaccacggg cttgggagca agcgccttct gcagcacagg     2880

aagccgaagc tggggtcagg tgaggtcgct acccctggag gtctggcata agggccccac     2940

cctcaggtct cctacactgg ccccatttta ctttggggtc caaggacagg atggtcaaca     3000

gggcagggtg gacagcgtgc cagcgccgcg cagggccacc tccctgggtg gatgcatcac     3060

actaaggaag tgagtgccaa ggggatttag tggtgtggtt ctttcaaagg gaggtcaggg     3120

tcaatgggaa tctgctcgga cactcaacat gggggtgggt gcactccttg gaggaggagg     3180

aacacgttca ggggattgtg aggtcttgca caagccacgt ggggcacctt ggcttcccgg     3240

caggaggtgg acacccagcc agaggcctgg ctcaaggtga cctcaccttc accatgggct     3300

tcctgggtgc gcgggcctga gcgcaggttg ttttgtacat attggaatat gtgttaactt     3360

atgccccgca tcccaactca cacggaagca cgggtcttgt ctcagtctct tcgctgcatt     3420

tggaaagcag tctcctctcg ggccagcgcc gggctgaggt gtccagaggc ggcggcagct     3480

ggcagtgccc tcagccccca agtgtccagc ctggcacttc ccattcaggc cacctgcttt     3540

gggtcaacag ttcctttgcc agcagcatct cctaaattgt aaggactctg tccaccgggg     3600

ccctcccagg gctgtgagga cggaaacagg cagggagtgg agctaacagc ttagtcacca     3660

ggacccccag acctgcaaac gtcccctcct ggaaggggaa gccaggaaca gcagaactgc     3720

ccacaaaaca aggctgtgaa cttttcggga actggaactg tttaacttga acccaggatt     3780

gtttaaagct ttatttattt atagcttctt cttaaaaaaa agtgttgaag aaattttttg     3840

gttattcata caaaaaaatg agttgatgat ggaaaagcaa gtcataatca tctaattgtt     3900

tttgtctagg tcgagaatga atgttagctg atgaaataaa ccctgacaag gaaaaaaaaa     3960

aaaaaa                                                                3966


<210>  1953
<211>  3966
<212>  DNA
<213>  homo sapiens

<400>  1953
gcgccccgcg cccgggcccc ggcgatggtg acacatgcgg cggcggcgcg ccggcggcag       60

gaccatggtt gagcgcgcca gcaagttcgt gctggtggtg gcgggctcgg tgtgcttcat      120

gctcatcttg taccagtacg cgggcccagg actgagcctg ggcgcgcccg gcggccgcgc      180

gccgcccgac gacctggacc tgttccccac acccgacccc cactacgaga agaagtacta      240

cttcccggtc cgcgagctgg agcgctcgct gcgcttcgac atgaagggcg acgacgtgat      300

cgtcttcctg cacatccaga agacgggcgg caccaccttc ggccgccacc tcgtgcagaa      360

cgtacgcctc gaggtgccgt gcgactgccg gcccggccag aagaagtgca cctgctaccg      420

gcccaaccgc cgcgagactt ggctcttctc ccgcttctcc accggctgga gctgcgggct      480

gcacgccgac tggaccgagc tcaccaactg cgtgcccggc gtgctggacc gccgcgactc      540

cgccgcgctg cgcacgccca ggaagttcta ctacatcacc ctgctacgag accccgtgtc      600

ccgctacctg agcgagtggc ggcatgtgca gaggggtgcc acgtggaaga cgtcgttgca      660

tatgtgtgat gggcgcacgc ccacgcctga ggagctgccg ccctgctacg agggcacgga      720

ctggtcgggc tgcacgctac aggagttcat ggactgcccg tacaacctgg ccaacaaccg      780

ccaggtgcgc atgctggccg acctgagcct ggtgggctgc tacaacctgt ccttcatccc      840

cgagggcaag cgggcccagc tgctgctcga gagcgccaag aagaacctgc ggggcatggc      900

cttcttcggc ctgaccgagt tccagcgcaa gacgcagtac ctgttcgagc ggacgttcaa      960

cctcaagttc atccggccct tcatgcagta caatagcacg cgggcgggcg gcgtggaggt     1020

ggatgaagac accatccggc gcatcgagga gctcaacgac ctggacatgc agctgtacga     1080

ctacgccaag gacctcttcc agcagcgcta ccagtacaag cggcagctgg agcgcaggga     1140

gcagcgcctg aggagccgcg aggagcgtct gctgcaccgg gccaaggagg cactgccgcg     1200

ggaggatgcc gacgagccgg gccgcgtgcc caccgaggac tacatgagcc acatcattga     1260

gaagtggtag tggcggtggt ggccacgggg aggcctcttg gggggtgtgg gggataaaac     1320

aggacagacg acaggtccac ccaagactgt caagggatga gcatcccaaa cctgctccac     1380

agaggtagct gcgtcctgaa aaaaaacaga gcagggatgt agtggggctg ggcagggatg     1440

ggggcttgag aaatcaacag gtgcagccca gtgggtcaga ggaaagcgtg ctcgaaggat     1500

gccatggtca gggcagggcc tccagagcag gtgttgtgcc tggagctgct ctcctggcct     1560

ccttggattt atcgcaaaaa ctgaaggttt gcgcaagaga cgaggacagc ggaaagtgga     1620

cctgccaggc cgggagtgtg tccctcacca actatgcaca cagcactcgc tcttagctcc     1680

tctgtccggg ctactaggag tgagaccagc ttctggcaac tgccccagct ccaggccatc     1740

ccatagcccc tcctcttctg gctgccccca atgccccgag gcctggggag cccccagctc     1800

acccatctgt agctccctca aagtcagggc ccaccccatc tgaggcagag aagactcgag     1860

tccagccccc aggaagcctg ctcccctctc tggcccatgg tcctgcttca tgctttgggt     1920

caggaggcca aagctgatgt tcaggcccca cccactccct acagtcctca gaccaaggag     1980

gggtttgggt agtaggcccg agctgcattg ccggccttcc tcgggccaac tggcagccca     2040

ggagtgggga ggctttggcc agggatgctg ccacttgtgc gtgagtccgc ggctggccct     2100

tggaggtgac catccaggca ggcctggctc agactggaag ggctggggac cgagggctcc     2160

cctgcctctg ttctcctttc tgacccactg ggatttgcta gcaggctgcc ccagccccat     2220

caccgaaaca catactcaag agctcaaata ccactgctcc caccagcgta cggattaagt     2280

tcatcaggct tccatcggct ggagcatggg accatagccc ctgcccagga gccgtaccct     2340

cggaccacag tggctctgta tggccaggaa ctgggactcg agctttcaga ttctcaacta     2400

gccttggcaa aacagctgta ggtggcctcc ctgacaacag acactcagcc ctccccaccc     2460

tggctctcct tgcatttccc catgctcccc accccctggc aaaaggctgg ccatgctctg     2520

ttcccagcag ccgcgcaggt ttccccactg gctgcaatgg ccctaccaaa agccatgttg     2580

catatccgtt gtaagcacgt gccctgtgcc ctgtccccat tccttatgcc ctaggaggcc     2640

aagctggtgt ctctaggagg gcccacacag gcaccctgga tcccccagag agtagattgg     2700

tgtgctcagg ccgcaggctg actcagaggt agggcagtgg gctctgcagg ccacctggct     2760

ggggttggtg ggggtcctct ctcctgcccc agcttccact cagccaccac agttgccaca     2820

ccatggggtg gagacgtggg tcaccacggg cttgggagca agcgccttct gcagcacagg     2880

aagccgaagc tggggtcagg tgaggtcgct acccctggag gtctggcata agggccccac     2940

cctcaggtct cctacactgg ccccatttta ctttggggtc caaggacagg atggtcaaca     3000

gggcagggtg gacagcgtgc cagcgccgcg cagggccacc tccctgggtg gatgcatcac     3060

actaaggaag tgagtgccaa ggggatttag tggtgtggtt ctttcaaagg gaggtcaggg     3120

tcaatgggaa tctgctcgga cactcaacat gggggtgggt gcactccttg gaggaggagg     3180

aacacgttca ggggattgtg aggtcttgca caagccacgt ggggcacctt ggcttcccgg     3240

caggaggtgg acacccagcc agaggcctgg ctcaaggtga cctcaccttc accatgggct     3300

tcctgggtgc gcgggcctga gcgcaggttg ttttgtacat attggaatat gtgttaactt     3360

atgccccgca tcccaactca cacggaagca cgggtcttgt ctcagtctct tcgctgcatt     3420

tggaaagcag tctcctctcg ggccagcgcc gggctgaggt gtccagaggc ggcggcagct     3480

ggcagtgccc tcagccccca agtgtccagc ctggcacttc ccattcaggc cacctgcttt     3540

gggtcaacag ttcctttgcc agcagcatct cctaaattgt aaggactctg tccaccgggg     3600

ccctcccagg gctgtgagga cggaaacagg cagggagtgg agctaacagc ttagtcacca     3660

ggacccccag acctgcaaac gtcccctcct ggaaggggaa gccaggaaca gcagaactgc     3720

ccacaaaaca aggctgtgaa cttttcggga actggaactg tttaacttga acccaggatt     3780

gtttaaagct ttatttattt atagcttctt cttaaaaaaa agtgttgaag aaattttttg     3840

gttattcata caaaaaaatg agttgatgat ggaaaagcaa gtcataatca tctaattgtt     3900

tttgtctagg tcgagaatga atgttagctg atgaaataaa ccctgacaag gaaaaaaaaa     3960

aaaaaa                                                                3966


<210>  1954
<211>  2166
<212>  DNA
<213>  homo sapiens

<400>  1954
gcggcgggag cgcgcccgtt gcaagatggc ggcggccatg ctgggccccg gggctgtgtg       60

tgcgcagcgg gcggcggcgc ggcccggaag gctggcgcgg cgacggcgtt agcccggccc      120

tcggcccctc tttgcggccg ctccctccgc ctattccctc cttgctcgag atggatctgc      180

ccgtgggccc cggcgcggcg gggcccagca acgtcccggc cttcctgacc aagctgtgga      240

ccctcgtgag cgacccggac accgacgcgc tcatctgctg gagcccgagc gggaacagct      300

tccacgtgtt cgaccagggc cagtttgcca aggaggtgct gcccaagtac ttcaagcaca      360

acaacatggc cagcttcgtg cggcagctca acatgtatgg cttccggaaa gtggtccaca      420

tcgagcaggg cggcctggtc aagccagaga gagacgacac ggagttccag cacccatgct      480

tcctgcgtgg ccaggagcag ctccttgaga acatcaagag gaaagtgacc agtgtgtcca      540

ccctgaagag tgaagacata aagatccgcc aggacagcgt caccaagctg ctgacggacg      600

tgcagctgat gaaggggaag caggagtgca tggactccaa gctcctggcc atgaagcatg      660

agaatgaggc tctgtggcgg gaggtggcca gccttcggca gaagcatgcc cagcaacaga      720

aagtcgtcaa caagctcatt cagttcctga tctcactggt gcagtcaaac cggatcctgg      780

gggtgaagag aaagatcccc ctgatgctga acgacagtgg ctcagcacat tccatgccca      840

agtatagccg gcagttctcc ctggagcacg tccacggctc gggcccctac tcggccccct      900

ccccagccta cagcagctcc agcctctacg cccctgatgc tgtggccagc tctggaccca      960

tcatctccga catcaccgag ctggctcctg ccagccccat ggcctccccc ggcgggagca     1020

tagacgagag gcccctatcc agcagccccc tggtgcgtgt caaggaggag ccccccagcc     1080

cgcctcagag cccccgggta gaggaggcga gtcccgggcg cccatcttcc gtggacaccc     1140

tcttgtcccc gaccgccctc attgactcca tcctgcggga gagtgaacct gcccccgcct     1200

ccgtcacagc cctcacggac gccaggggcc acacggacac cgagggccgg cctccctccc     1260

ccccgcccac ctccacccct gaaaagtgcc tcagcgtagc ctgcctggac aagaatgagc     1320

tcagtgacca cttggatgct atggactcca acctggataa cctgcagacc atgctgagca     1380

gccacggctt cagcgtggac accagtgccc tgctggacct gttcagcccc tcggtgaccg     1440

tgcccgacat gagcctgcct gaccttgaca gcagcctggc cagtatccaa gagctcctgt     1500

ctccccagga gccccccagg cctcccgagg cagagaacag cagcccggat tcagggaagc     1560

agctggtgca ctacacagcg cagccgctgt tcctgctgga ccccggctcc gtggacaccg     1620

ggagcaacga cctgccggtg ctgtttgagc tgggagaggg ctcctacttc tccgaagggg     1680

acggcttcgc cgaggacccc accatctccc tgctgacagg ctcggagcct cccaaagcca     1740

aggaccccac tgtctcctag aggccccgga ggagctgggc cagccgccca cccccacccc     1800

cagtgcaggg ctggtcttgg ggaggcaggg cagcctcgcg gtcttgggca ctggtgggtc     1860

ggccgccata gccccagtag gacaaacggg ctcgggtctg ggcagcacct ctggtcagga     1920

gggtcaccct ggcctgccag tctgccttcc cccaaccccg tgtcctgtgg tttggttggg     1980

gcttcacagc cacacctgga ctgaccctgc aggttgttca tagtcagaat tgtattttgg     2040

atttttacac aactgtcccg ttccccgctc cacagagata cacagatata tacacacagt     2100

ggatggacgg acaagacagg cagagatcta taaacagaca ggctctatgc taaaaaaaaa     2160

aaaaaa                                                                2166


<210>  1955
<211>  2166
<212>  DNA
<213>  homo sapiens

<400>  1955
gcggcgggag cgcgcccgtt gcaagatggc ggcggccatg ctgggccccg gggctgtgtg       60

tgcgcagcgg gcggcggcgc ggcccggaag gctggcgcgg cgacggcgtt agcccggccc      120

tcggcccctc tttgcggccg ctccctccgc ctattccctc cttgctcgag atggatctgc      180

ccgtgggccc cggcgcggcg gggcccagca acgtcccggc cttcctgacc aagctgtgga      240

ccctcgtgag cgacccggac accgacgcgc tcatctgctg gagcccgagc gggaacagct      300

tccacgtgtt cgaccagggc cagtttgcca aggaggtgct gcccaagtac ttcaagcaca      360

acaacatggc cagcttcgtg cggcagctca acatgtatgg cttccggaaa gtggtccaca      420

tcgagcaggg cggcctggtc aagccagaga gagacgacac ggagttccag cacccatgct      480

tcctgcgtgg ccaggagcag ctccttgaga acatcaagag gaaagtgacc agtgtgtcca      540

ccctgaagag tgaagacata aagatccgcc aggacagcgt caccaagctg ctgacggacg      600

tgcagctgat gaaggggaag caggagtgca tggactccaa gctcctggcc atgaagcatg      660

agaatgaggc tctgtggcgg gaggtggcca gccttcggca gaagcatgcc cagcaacaga      720

aagtcgtcaa caagctcatt cagttcctga tctcactggt gcagtcaaac cggatcctgg      780

gggtgaagag aaagatcccc ctgatgctga acgacagtgg ctcagcacat tccatgccca      840

agtatagccg gcagttctcc ctggagcacg tccacggctc gggcccctac tcggccccct      900

ccccagccta cagcagctcc agcctctacg cccctgatgc tgtggccagc tctggaccca      960

tcatctccga catcaccgag ctggctcctg ccagccccat ggcctccccc ggcgggagca     1020

tagacgagag gcccctatcc agcagccccc tggtgcgtgt caaggaggag ccccccagcc     1080

cgcctcagag cccccgggta gaggaggcga gtcccgggcg cccatcttcc gtggacaccc     1140

tcttgtcccc gaccgccctc attgactcca tcctgcggga gagtgaacct gcccccgcct     1200

ccgtcacagc cctcacggac gccaggggcc acacggacac cgagggccgg cctccctccc     1260

ccccgcccac ctccacccct gaaaagtgcc tcagcgtagc ctgcctggac aagaatgagc     1320

tcagtgacca cttggatgct atggactcca acctggataa cctgcagacc atgctgagca     1380

gccacggctt cagcgtggac accagtgccc tgctggacct gttcagcccc tcggtgaccg     1440

tgcccgacat gagcctgcct gaccttgaca gcagcctggc cagtatccaa gagctcctgt     1500

ctccccagga gccccccagg cctcccgagg cagagaacag cagcccggat tcagggaagc     1560

agctggtgca ctacacagcg cagccgctgt tcctgctgga ccccggctcc gtggacaccg     1620

ggagcaacga cctgccggtg ctgtttgagc tgggagaggg ctcctacttc tccgaagggg     1680

acggcttcgc cgaggacccc accatctccc tgctgacagg ctcggagcct cccaaagcca     1740

aggaccccac tgtctcctag aggccccgga ggagctgggc cagccgccca cccccacccc     1800

cagtgcaggg ctggtcttgg ggaggcaggg cagcctcgcg gtcttgggca ctggtgggtc     1860

ggccgccata gccccagtag gacaaacggg ctcgggtctg ggcagcacct ctggtcagga     1920

gggtcaccct ggcctgccag tctgccttcc cccaaccccg tgtcctgtgg tttggttggg     1980

gcttcacagc cacacctgga ctgaccctgc aggttgttca tagtcagaat tgtattttgg     2040

atttttacac aactgtcccg ttccccgctc cacagagata cacagatata tacacacagt     2100

ggatggacgg acaagacagg cagagatcta taaacagaca ggctctatgc taaaaaaaaa     2160

aaaaaa                                                                2166


<210>  1956
<211>  4978
<212>  DNA
<213>  homo sapiens

<400>  1956
ggtttccgga gctgcggcgg cgcagactgg gagggggagc cgggggttcc gacgtcgcag       60

ccgagggaac aagccccaac cggatcctgg acaggcaccc cggcttggcg ctgtctctcc      120

ccctcggctc ggagaggccc ttcggcctga gggagcctcg ccgcccgtcc ccggcacacg      180

cgcagccccg gcctctcggc ctctgccgga gaaacagttg ggacccctga ttttagcagg      240

atggcccaat ggaatcagct acagcagctt gacacacggt acctggagca gctccatcag      300

ctctacagtg acagcttccc aatggagctg cggcagtttc tggccccttg gattgagagt      360

caagattggg catatgcggc cagcaaagaa tcacatgcca ctttggtgtt tcataatctc      420

ctgggagaga ttgaccagca gtatagccgc ttcctgcaag agtcgaatgt tctctatcag      480

cacaatctac gaagaatcaa gcagtttctt cagagcaggt atcttgagaa gccaatggag      540

attgcccgga ttgtggcccg gtgcctgtgg gaagaatcac gccttctaca gactgcagcc      600

actgcggccc agcaaggggg ccaggccaac caccccacag cagccgtggt gacggagaag      660

cagcagatgc tggagcagca ccttcaggat gtccggaaga gagtgcagga tctagaacag      720

aaaatgaaag tggtagagaa tctccaggat gactttgatt tcaactataa aaccctcaag      780

agtcaaggag acatgcaaga tctgaatgga aacaaccagt cagtgaccag gcagaagatg      840

cagcagctgg aacagatgct cactgcgctg gaccagatgc ggagaagcat cgtgagtgag      900

ctggcggggc ttttgtcagc gatggagtac gtgcagaaaa ctctcacgga cgaggagctg      960

gctgactgga agaggcggca acagattgcc tgcattggag gcccgcccaa catctgccta     1020

gatcggctag aaaactggat aacgtcatta gcagaatctc aacttcagac ccgtcaacaa     1080

attaagaaac tggaggagtt gcagcaaaaa gtttcctaca aaggggaccc cattgtacag     1140

caccggccga tgctggagga gagaatcgtg gagctgttta gaaacttaat gaaaagtgcc     1200

tttgtggtgg agcggcagcc ctgcatgccc atgcatcctg accggcccct cgtcatcaag     1260

accggcgtcc agttcactac taaagtcagg ttgctggtca aattccctga gttgaattat     1320

cagcttaaaa ttaaagtgtg cattgacaaa gactctgggg acgttgcagc tctcagagga     1380

tcccggaaat ttaacattct gggcacaaac acaaaagtga tgaacatgga agaatccaac     1440

aacggcagcc tctctgcaga attcaaacac ttgaccctga gggagcagag atgtgggaat     1500

gggggccgag ccaattgtga tgcttccctg attgtgactg aggagctgca cctgatcacc     1560

tttgagaccg aggtgtatca ccaaggcctc aagattgacc tagagaccca ctccttgcca     1620

gttgtggtga tctccaacat ctgtcagatg ccaaatgcct gggcgtccat cctgtggtac     1680

aacatgctga ccaacaatcc caagaatgta aactttttta ccaagccccc aattggaacc     1740

tgggatcaag tggccgaggt cctgagctgg cagttctcct ccaccaccaa gcgaggactg     1800

agcatcgagc agctgactac actggcagag aaactcttgg gacctggtgt gaattattca     1860

gggtgtcaga tcacatgggc taaattttgc aaagaaaaca tggctggcaa gggcttctcc     1920

ttctgggtct ggctggacaa tatcattgac cttgtgaaaa agtacatcct ggccctttgg     1980

aacgaagggt acatcatggg ctttatcagt aaggagcggg agcgggccat cttgagcact     2040

aagcctccag gcaccttcct gctaagattc agtgaaagca gcaaagaagg aggcgtcact     2100

ttcacttggg tggagaagga catcagcggt aagacccaga tccagtccgt ggaaccatac     2160

acaaagcagc agctgaacaa catgtcattt gctgaaatca tcatgggcta taagatcatg     2220

gatgctacca atatcctggt gtctccactg gtctatctct atcctgacat tcccaaggag     2280

gaggcattcg gaaagtattg tcggccagag agccaggagc atcctgaagc tgacccaggt     2340

agcgctgccc catacctgaa gaccaagttt atctgtgtga caccaacgac ctgcagcaat     2400

accattgacc tgccgatgtc cccccgcact ttagattcat tgatgcagtt tggaaataat     2460

ggtgaaggtg ctgaaccctc agcaggaggg cagtttgagt ccctcacctt tgacatggag     2520

ttgacctcgg agtgcgctac ctcccccatg tgaggagctg agaacggaag ctgcagaaag     2580

atacgactga ggcgcctacc tgcattctgc cacccctcac acagccaaac cccagatcat     2640

ctgaaactac taactttgtg gttccagatt ttttttaatc tcctacttct gctatctttg     2700

agcaatctgg gcacttttaa aaatagagaa atgagtgaat gtgggtgatc tgcttttatc     2760

taaatgcaaa taaggatgtg ttctctgaga cccatgatca ggggatgtgg cggggggtgg     2820

ctagagggag aaaaaggaaa tgtcttgtgt tgttttgttc ccctgccctc ctttctcagc     2880

agctttttgt tattgttgtt gttgttctta gacaagtgcc tcctggtgcc tgcggcatcc     2940

ttctgcctgt ttctgtaagc aaatgccaca ggccacctat agctacatac tcctggcatt     3000

gcacttttta accttgctga catccaaata gaagatagga ctatctaagc cctaggtttc     3060

tttttaaatt aagaaataat aacaattaaa gggcaaaaaa cactgtatca gcatagcctt     3120

tctgtattta agaaacttaa gcagccgggc atggtggctc acgcctgtaa tcccagcact     3180

ttgggaggcc gaggcggatc ataaggtcag gagatcaaga ccatcctggc taacacggtg     3240

aaaccccgtc tctactaaaa gtacaaaaaa ttagctgggt gtggtggtgg gcgcctgtag     3300

tcccagctac tcgggaggct gaggcaggag aatcgcttga acctgagagg cggaggttgc     3360

agtgagccaa aattgcacca ctgcacactg cactccatcc tgggcgacag tctgagactc     3420

tgtctcaaaa aaaaaaaaaa aaaaaagaaa cttcagttaa cagcctcctt ggtgctttaa     3480

gcattcagct tccttcaggc tggtaattta tataatccct gaaacgggct tcaggtcaaa     3540

cccttaagac atctgaagct gcaacctggc ctttggtgtt gaaataggaa ggtttaagga     3600

gaatctaagc attttagact tttttttata aatagactta ttttcctttg taatgtattg     3660

gccttttagt gagtaaggct gggcagaggg tgcttacaac cttgactccc tttctccctg     3720

gacttgatct gctgtttcag aggctaggtt gtttctgtgg gtgccttatc agggctggga     3780

tacttctgat tctggcttcc ttcctgcccc accctcccga ccccagtccc cctgatcctg     3840

ctagaggcat gtctccttgc gtgtctaaag gtccctcatc ctgtttgttt taggaatcct     3900

ggtctcagga cctcatggaa gaagaggggg agagagttac aggttggaca tgatgcacac     3960

tatggggccc cagcgacgtg tctggttgag ctcagggaat atggttctta gccagtttct     4020

tggtgatatc cagtggcact tgtaatggcg tcttcattca gttcatgcag ggcaaaggct     4080

tactgataaa cttgagtctg ccctcgtatg agggtgtata cctggcctcc ctctgaggct     4140

ggtgactcct ccctgctggg gccccacagg tgaggcagaa cagctagagg gcctccccgc     4200

ctgcccgcct tggctggcta gctcgcctct cctgtgcgta tgggaacacc tagcacgtgc     4260

tggatgggct gcctctgact cagaggcatg gccggatttg gcaactcaaa accaccttgc     4320

ctcagctgat cagagtttct gtggaattct gtttgttaaa tcaaattagc tggtctctga     4380

attaaggggg agacgacctt ctctaagatg aacagggttc gccccagtcc tcctgcctgg     4440

agacagttga tgtgtcatgc agagctctta cttctccagc aacactcttc agtacataat     4500

aagcttaact gataaacaga atatttagaa aggtgagact tgggcttacc attgggttta     4560

aatcataggg acctagggcg agggttcagg gcttctctgg agcagatatt gtcaagttca     4620

tggccttagg tagcatgtat ctggtcttaa ctctgattgt agcaaaagtt ctgagaggag     4680

ctgagccctg ttgtggccca ttaaagaaca gggtcctcag gccctgcccg cttcctgtcc     4740

actgccccct ccccatcccc agcccagccg agggaatccc gtgggttgct tacctaccta     4800

taaggtggtt tataagctgc tgtcctggcc actgcattca aattccaatg tgtacttcat     4860

agtgtaaaaa tttatattat tgtgaggttt tttgtctttt tttttttttt ttttttttgg     4920

tatattgctg tatctacttt aacttccaga aataaacgtt atataggaac cgtaaaaa       4978


<210>  1957
<211>  2400
<212>  DNA
<213>  homo sapiens

<400>  1957
tccgctccgt tcggccggtt ctcccgggaa gctattaata gcattacgtc agcctgggac       60

tggcaacacg gagtaaacga ccgcgccgcc agcctgaggg ctataaaagg ggtgatgcaa      120

cgctctccaa gccacagtcg cacgcagcca ggcgcgcact gcacagctct cttctctcgc      180

cgccgcccga gcgcaccctt cagcccgcgc gccggccgtg agtcctcggt gctcgcccgc      240

cggccagaca aacagcccgc ccgaccccgt cccgaccctg gccgccccga gcggagcctg      300

gagcaaaatg atgcttcaac acccaggcca ggtctctgcc tcggaagtga gtgcttctgc      360

catcgtcccc tgcctgtccc ctcctgggtc actggtgttt gaggattttg ctaacctgac      420

gccctttgtc aaggaagagc tgaggtttgc catccagaac aagcacctct gccaccggat      480

gtcctctgcg ctggaatcag tcactgtcag cgacagaccc ctcggggtgt ccatcacaaa      540

agccgaggta gcccctgaag aagatgaaag gaaaaagagg cgacgagaaa gaaataagat      600

tgcagctgca aagtgccgaa acaagaagaa ggagaagacg gagtgcctgc agaaactccc      660

aaggcccttt tgggtccaga agacctgcat atgggctgtt gactcatgca aatgaggtat      720

ctgaactgca gcttcagtat tagcagagcc acaggccgcc tctgtggcat caccagggtt      780

tctctgaaga agagggtctg cattttccta aacccagtgc tgctctccca tctcccatct      840

tcctctcgca gcttgatgag ccccggtgtg tcccaggtac acccctgcat ccaggcagca      900

gcccaggcca ccccctcctc actggccctt ggctcctttc ttgatgcctc tgttgcttgt      960

cccccaggag tcggagaagc tggaaagtgt gaatgctgaa ctgaaggctc agattgagga     1020

gctcaagaac gagaagcagc atttgatata catgctcaac cttcatcggc ccacgtgtat     1080

tgtccgggct cagaatggga ggactccaga agatgagaga aacctcttta tccaacagat     1140

aaaagaagga acattgcaga gctaagcagt cgtggtatgg gggcgactgg ggagtcctca     1200

ttgaatcctc attttatacc caaaaccctg aagccattgg agagctgtct tcctgtgtac     1260

ctctagaatc ccagcagcag agaaccatca aggcgggagg gcctgcagtg attcagcagg     1320

cccttcccat tctgccccag agtgggtctt ggaccagggc aagtgcatct ttgcctcaac     1380

tccaggattt aggccttaac acactggcca ttcttatgtt ccagatggcc cccagctggt     1440

gtcctgcccg cctttcatct ggattctaca aaaaaccagg atgcccaccg ttaggattca     1500

ggcagcagtg tctgtacctc gggtgggagg gatggggcca tctccttcac cgtggctacc     1560

attgtcactc gtaggggatg tggagtgaga acagcattta gtgaagttgt gcaacggcca     1620

gggttgtgct ttctagcaaa tatgctgtta tgtccagaaa ttgtgtgtgc aagaaaacta     1680

ggcaatgtac tcttccgatg tttgtgtcac acaacactga tgtgactttt atatgctttt     1740

tctcagatct ggtttctaag agttttgggg ggcggggctg tcaccacgtg cagtatctca     1800

agatattcag gtggccagaa gagcttgtca gcaagaggag gacagaattc tcccagcgtt     1860

aacacaaaat ccatgggcag tatgatggca ggtcctctgt tgcaaactca gttccaaagt     1920

cacaggaaga aagcagaaag ttcaacttcc aaagggttag gactctccac tcaatgtctt     1980

aggtcaggag ttgtgtctag gctggaagag ccaaagaata ttccattttc ctttccttgt     2040

ggttgaaaac cacagtcagt ggagagatgt ttggaaacca cagtcagtgg agcctgggtg     2100

gtacccaggc tttagcatta ttggatgtca atagcattgt ttttgtcatg tagctgtttt     2160

aagaaatctg gcccagggtg tttgcagctg tgagaagtca ctcacactgg ccacaaggac     2220

gctggctact gtctattaaa attctgatgt ttctgtgaaa ttctcagagt gtttaattgt     2280

actcaatggt atcattacaa ttttctgtaa gagaaaatat tacttattta tcctagtatt     2340

cctaacctgt cagaataata aatattggaa ccaagacatg gtaaacaaaa aaaaaaaaaa     2400


<210>  1958
<211>  1249
<212>  DNA
<213>  homo sapiens

<400>  1958
gtcccgacgc ctcccgcccc cgcagttcct tggagagctt ggagccgcgc gccggaggga       60

ataggaaagc ttggttacaa cccgggacac ccggagcttc aggatggttc gtactaagac      120

atggaccctg aagaagcact ttgttggcta tcctactaat agtgactttg agttgaagac      180

agctgagctc ccacccttaa aaaatggaga ggtcctgctt gaagctttgt tcctcaccgt      240

ggatccctac atgagagtgg cagccaaaag attgaaggaa ggtgatacaa tgatggggca      300

gcaagtggcc aaagttgtgg aaagtaaaaa tgtagcccta ccaaaaggaa ctattgtact      360

ggcttctcca ggctggacaa cgcactccat ttctgatggg aaagatctgg aaaagctgct      420

gacagagtgg ccagacacaa taccactgtc tttggctctg gggacagttg gcatgccagg      480

cctgactgcc tactttggcc tacttgaaat ctgtggtgtg aagggtggag aaacagtgat      540

ggttaatgca gcagctggag ctgtgggctc agtcgtgggg cagattgcaa agctcaaggg      600

ctgcaaagtt gttggagcag tagggtctga tgaaaaggtt gcctaccttc aaaagcttgg      660

atttgatgtc gtctttaact acaagacggt agagtctttg gaagaaacct tgaagaaagc      720

gtctcctgat ggttatgatt gttattttga taatgtaggt ggagagtttt caaacactgt      780

tatcggccag atgaagaaat ttggaaggat tgccatatgt ggagccatct ctacatataa      840

cagaaccggc ccacttcccc caggcccacc cccagagatt gttatctatc aggagcttcg      900

catggaagct tttgtcgtct accgctggca aggagatgcc cgccaaaaag ctctgaagga      960

cttgctgaaa tgggtcttag agggtaaaat ccagtacaag gaatatatca ttgaaggatt     1020

tgaaaacatg ccagctgcat ttatgggaat gctgaaagga gataatttgg ggaagacaat     1080

agtgaaagca tgaaaaagag gacacatgga atctggaggc catttagatg attagttaat     1140

ttgtttttca ccatttagca aaaatgtata ctaccttaaa tgtcttaaga aatagtactc     1200

ataatgagtt tgagctactt aataaaatac atttaagtgg tatgtaaaa                 1249


<210>  1959
<211>  1496
<212>  DNA
<213>  homo sapiens

<400>  1959
ggcggctgct gaacggcgga gtggcgtgga cctcatgtag caatgacaat ggaaggggcc       60

agcgggtcga gttttggaat agacacgatt ttgtccagtg ccagttcagg cagcccaggc      120

atgatgaatg gagatttccg cccgctcggt gaggccagga ccgcggattt taggagtcag      180

gccaccccat ctccctgttc ggagattgat accgtaggga cggcgccttc ttctcctatc      240

tcagtcacca tggagccccc ggagccgcat ctggtagcag acgcgaccca gcatcatcac      300

cacctccacc acagccagca gccgccgccg ccggccgcgg ccccgacgca aagtttgcag      360

cctttgcccc aacagcagca gccgctgccg ccacagcagc cgccgccgcc gcccccccag      420

cagctgggct cggccgcctc ggcccccagg acttccacgt cttctttttt aattaaggac      480

atcttgggcg acagcaaacc tctggcggca tgtgcaccct acagcaccag cgtatcctct      540

ccccaccaca ccccgaagca ggagagcaac gcagtgcacg agagcttcag gccaaagctc      600

gagcaggagg acagcaagac caaactcgac aagcgggagg attcccagag cgacatcaaa      660

tgccacggga caaaggagga aggagaccgg gagattacga gtagccgtga gagtccccct      720

gtgagagcca agaagcctcg aaaagcaagg acagcttttt ccgaccacca gctcaatcaa      780

ctggagcgta gctttgagcg gcagaagtac ctgagcgtgc aggatcgcat ggacctggct      840

gcagcgctca acctcactga cacccaagtc aagacctggt accagaaccg caggaccaag      900

tggaagcggc agacagcggt gggcctggag ttgctggccg aggcagggaa ctactcggcg      960

ctgcagagga tgtttccatc gccttatttc tatcacccaa gcctgctggg cagcatggac     1020

agcactacgg cggcggcggc tgccgctgcc atgtacagca gcatgtaccg gactcctcca     1080

gcaccccatc cccagctgca gcggcccctg gtgccccgtg tgctcatcca cggcctaggg     1140

cctgggggac agccagccct taatccattg tccagcccca tcccaggcac cccacacccc     1200

cggtgaaaac attgcagcga aggcactgca atcccttccc catatccctg cccaacccgg     1260

actgctgccc gtcctctccc tgctccaggc cactaggcct cccttgcagc caactctgga     1320

aggcagagga gtaagagagg aagatgctta ccagtgggca ggggaccccc aaagaggagc     1380

cagccctctg ctctccatct ccccacccct agaaacaggg ctggaaatct cccccacagc     1440

agtgtgactg gtgaaaatgc tgaccccaca cagagtgcaa ccagtaagtg aaaaca         1496


<210>  1960
<211>  2812
<212>  DNA
<213>  homo sapiens

<400>  1960
ggtgctcggc tcgcggggac tggcctcctt cggcagctgg aggcggtcac tcacgctggg       60

ctaggagctg aggcgagaag ggccatgcgg acggcgaggg agtccagagc cttgagcccg      120

gtgctcctcc ctcgcgcagc ggtggctctg cggccgctgg agtaaacact gcctttgttc      180

cctagcgcct cgtctttcgt cgccccgtgc cctcacgccg ccgggctctg gccggcccgc      240

cctcggtcct tgaaccccat ttcggctcgt gccgtgcgga tgcagctgcc gggcctgggt      300

ttgggcattg agcgggagga ggaggaggag cggcggcgcc tgggcggcat gcgatgggga      360

actgctgctg gacgcagtgc ttcggactgc ttcgcaagga agcggggcgg ctgcagcgag      420

taggcggcgg cggaggatcc aagtatttta gaacatgctc aagaggtgag cacttaacaa      480

tagagtttga gaatctagta gaaagtgatg aaggggagag cccaggaagc agtcataggc      540

ctcttactga ggaagaaatt gttgacctaa gagaaaggca ttatgattcc attgccgaaa      600

aacaaaaaga tcttgataag aaaattcaaa aagagcaaga aaggcagaga attgtgcagc      660

aatatcatcc ttccaacaat ggagaatatc aaagttcagg accagaagat gacttcgaat      720

cttgtttgag aaatatgaag tcacagtatg aagtttttcg aagtagtaga ctctcatcag      780

atgctacagt tttgacacca aatacagaaa gcagttgtga tttaatgacc aaaactaaat      840

caactagtgg aaatgacgac agcacatcct tagatctaga gtgggaagat gaagaaggaa      900

tgaatagaat gcttccaatg agagaacgtt ccaaaacaga ggaagacatt ctacgggcag      960

cacttaagta tagcaacaag aagactggaa gtaatcctac atcagcctct gatgattcca     1020

atgggctgga gtgggaaaat gattttgtta gtgccgaaat ggatgataat ggaaattccg     1080

agtattctgg atttgtaaat cctgtattag aactgtctga ttctggcata aggcattctg     1140

acacagatca acagactcga tagggtaaaa ttgtgtgacc ttgtttatca gttatgacca     1200

aatgttaaaa accaactaga atgtataagt gattgtgctt agcctttttg taagggagat     1260

gtgtaagaaa ccatgttgta aatgcttatt ttattacaaa ggagtaggga tgataggatc     1320

tgaattgata cagaattaag tgcaatttca tcatctgcct tctgcttttc aagaccaatt     1380

taatggtcct gtcatgttac tgattaaatt tactttgtct tgtctttata gcatttctgt     1440

ttactatggt agatttccac tttcaatttt taaaattaat tttactttga atgatttatg     1500

aagcctattt cattgtctaa ctatgaaaat attaagactt ttttgttaat tctcagccga     1560

tgtgaaggaa gcatgaggag ggatcgtcag attcagattt agaatagtgt tcccgtttcc     1620

agcattattt atttctatga cttctttgga ttttattatc taatagtaag tacagttgat     1680

gtgggtagat gactctaaga aatgctgaag tatcggcatt acatgtgttt atttacatgt     1740

cctagtatga taatgttgat tcaatctgaa caaaagataa tataaaaata acccttcaga     1800

gtttggacat ttcaagttgg taataataaa aaataatatt taagaagata tatatatata     1860

tatatttagt tttttccact tcattttaca tgccactata ttgactttaa ttgatataca     1920

gtattaagtt tttaggtgcc attattttta aaaaattcta tatttccaat gaacgatgtt     1980

agattttaca cagaacatat tctctgcatg atttcagaaa agaaaatcta aaaaggtaat     2040

acgggtattt caaataaaat cctttctggt atgaaaggct ccattgattt tattaagcct     2100

tcctttacct tgtagtacaa ggtgctttaa tgggatagaa ctaagcatat caatatctat     2160

aactgcattt tgtgctagac aattactgtt cttttctcta aaatgtatat gtcaatttac     2220

aaggccaggg atagaaaaca ctccataatt gctttccttg attttgctga ggatttggta     2280

tgattttagt aagcaaactg ttttttggtt tttccttaat gtttttaatt ttttttcctc     2340

ttgcaacaat gacggtgcat gttcttataa atataggaag gtccagatat aaatagtaac     2400

ctaaagttct tgctgtgctt aaaaaaaaaa atcatgtggc cctttcaata tttgaactgc     2460

taagcaatga catctgtagt tttatctcct tttttatgtc atagaaatta atatgatact     2520

ttaaatatgt aaatataata cattaggtaa tgctattatt tatatctgtc ttaacataat     2580

ttaagttgta gctgtgtctt ggaaatattt ttaaggtaat ctatattcac attgcctgtg     2640

ttaatgcttt ttaaagtttg tatacatcag atgtatattt ttggtttggc ataagctacg     2700

attgtaattt ttcttggctt tttgttcata aagaattttt tgaaggaatg gtaacaaatg     2760

gtaatttaca aatggttgtg aataaacaca tttttacact taaaggtaaa aa             2812


<210>  1961
<211>  2548
<212>  DNA
<213>  homo sapiens

<400>  1961
gtcgcgccga gggtgacgcg tggcgtagac gacgccgtcg gcctgcgcct gtcacccccc       60

tcctcccggg gtttgtagcg gaggaggagc gggcgccatg gcggttctac tggagaccac      120

tttaggcgac gtcgtcatcg acttgtacac cgaagaacgg ccgcgtgcct gcttgaattt      180

cttgaaactg tgcaaaataa aatattacaa ttattgcctt attcacaatg tacagaggga      240

ttttatcata caaactggcg atcctacagg gactggccgt ggaggagagt ctatctttgg      300

ccaactgtat ggtgatcaag caagcttttt tgaggcagaa aaagtcccaa gaattaagca      360

caagaagaaa ggcacagtgt ccatggtgaa taatggcagt gatcaacatg gatctcagtt      420

tcttatcacc acaggagaaa atctagatta tcttgatggt gtccatacgg tgtttggtga      480

ggtgacagaa ggcatggaca taattaagaa aattaatgag acctttgttg acaaggactt      540

tgtaccatat caggatatca ggataaatca tacggtgatt ttagatgatc catttgatga      600

ccctcctgat ttattaatcc ctgatcgatc accagaacct acaagggaac aattagatag      660

tggtcgaata ggagcagatg aagaaattga tgatttcaaa ggaagatcag ctgaggaagt      720

agaagaaata aaggcagaaa aagaggctaa aactcaggct atacttttgg agatggtggg      780

agacctacct gatgcagata ttaaacctcc agaaaatgta ctgtttgtgt gtaaattgaa      840

cccagtgacc acagatgagg atctggaaat aatattctct agatttgggc caataagaag      900

ttgtgaagtt atccgagact ggaagacagg agagtccctc tgttacgctt ttattgaatt      960

tgaaaaggaa gaagattgtg agaaagcatt cttcaaaatg gacaatgtgc ttatagatga     1020

cagaagaata catgtggatt ttagccagtc ggttgcaaag gttaaatgga aaggaaaagg     1080

tgggaaatac accaagagtg atttcaagga gtatgaaaaa gaacaggata aaccacctaa     1140

tttggttctg aaagataaag taaagcccaa acaggataca aaatacgatc ttatattaga     1200

tgagcaggcc gaagactcaa aatcaagtca ctcacacaca agtaaaaaac acaagaagaa     1260

aacccatcac tgttctgaag agaaagaaga tgaggactac atgccaatca aaaatactaa     1320

tcaggatatc tatagagaaa tggggtttgg tcactatgaa gaagaagaaa gctgttggga     1380

gaaacaaaag agtgaaaaga gagaccgaac tcagaaccga agtcgtagcc gatctcgaga     1440

gagggatggc cattatagta atagtcataa atcaaaatac caaacagatc tttatgaaag     1500

agaaaggagt aaaaagagag accgaagcag aagtccaaag aagtccaaag ataaagaaaa     1560

atctaagtat agatgaaaga tgaagaggca gaattgagag gctaacatat ttactcttgt     1620

ctaacttaag agtgccagga aagcagatgc ttagattttg tgtcaaagct tgttattttt     1680

ttcatactag gattatggtc tttagattaa tactgattat atagagcacg gaaagataaa     1740

gaattgaaca ttttctttgt atactttttt acactaattt tattgttata cataaatggt     1800

agtcttcatt tttgaagtct tacattttca ctcttttttt aatgaagtat ttcatactac     1860

aaaaatacat aaacgtatat ataaagggat aataaatgta aatatctgtg tactcatcag     1920

ccagcttaag atacagatgt tgtcgacatt ttagaagttc cctaaggccc tctccctctc     1980

aaataattat ttggaatttt gtgtttgtca tttgtctatt atagttttac aacatacgta     2040

tgtatctgta agtgaaatgt taattttgta tgtttctgaa ttttatataa atggcaaaat     2100

gtttacttct gtgactttct ttcattttta ttgctatata gtattatata aatatactac     2160

aacttattca ttcttgatgg acatttgagt tttgtttatt tgtttttgct gttgaaacaa     2220

tgctgctgtg aacattgtat ctagcagtta tattgcttga tatattgata aaataatgcc     2280

aaatttgtgt tctgaagtga ctgtactagt ttatacctct cttggcactg tgagttacct     2340

ttgtttcata gcatctccaa cacttaagtt cagacttaaa aatttgccaa cctagtggat     2400

gttaagtggt atctacctgt gatttccagc aagattactg ttatctctgc tcttccatgt     2460

gtaagatgtc atttttttcc tggctgcttt taaggttttc tgtcactggt tgtaagaagt     2520

ttgattatga tgtgaaaaaa aaaaaaaa                                        2548


<210>  1962
<211>  8210
<212>  DNA
<213>  homo sapiens

<400>  1962
gatctgatga atccaaggag tggagcaaga ggcagatttt ggacacggtt atgagaatga       60

cagaaactgc ctaaagcatt tatgctctgg cattcgtccc tgtttctgga ggtccagtaa      120

gcgcttccca acagaggacc atctgatgat tcataggcac aaacatgaaa tgactttgaa      180

gtttccttca ataaaaacag acaatatgtt atcagatcaa actccgaccc caacgagatt      240

cctgaagaac tgcgaggagg tgggcctctt cagcgagctg gactgctccc tggagcacga      300

gttcaggaag gctcaggaag aggagagcag caagcggaat atctcgatgc ataatgcagt      360

tggtggggcc atgacggggc ccggaactca ccagcttagc agcgctcggc tgcccaacca      420

tgacaccaac gttgtgattc agcaagccat gccgtcgcct cagtccagct ctgtcatcac      480

tcaggcacct tccaccaacc gccagatcgg gcctgtccca ggctctctat cttctctgct      540

acatctccac aacagacaga gacagcccat gccagcctcc atgcctggga ccctgcccaa      600

ccctacaatg ccaggatctt ccgccgtctt gatgccaatg gagcgacaaa tgtcagtgaa      660

ctccagcatc atggggatgc aaggtccaaa tctcagcaac ccctgtgctt ctccccaggt      720

ccagccaatg cattcagaag ccaaaatgag gttgaaggct gcattgactc accaccctgc      780

tgccatgtca aatgggaaca tgaacaccat gggacacatg atggagatga tgggctcccg      840

gcaggaccag acgccacacc atcacatgca ctcgcacccg catcagcacc agacactgcc      900

accccatcac ccttacccac accagcacca gcacccagca caccatcctc accctcaacc      960

ccatcaccag cagaaccatc cacatcacca ctcccattcc caccttcatg cacacccagc     1020

acatcaccag acctcgccac atccgcccct gcacaccggc aaccaagcac aggtttcacc     1080

agcaacacaa cagatgcagc caacccagac aatacagcca ccccagccca caggggggcg     1140

ccggcgaagg gtggtagacg aggatccgga cgagaggcgg cggaaatttc tggaacggaa     1200

ccgggcagct gccacccgct gcagacagaa gaggaaggtc tgggtgatgt cattggaaaa     1260

gaaagcagaa gaactcaccc agacaaacat gcagcttcag aatgaagtgt ctatgttgaa     1320

aaatgaggtg gcccagctga aacagttgtt gttaacacat aaagactgcc caataacagc     1380

catgcagaaa gaatcacaag gatatctaag tccagagagt agccctcctg ctagtcctgt     1440

cccagcttgc tcccagcaac aagtcatcca gcataatacc atcactactt cctcatcggt     1500

cagcgaggtg gtaggaagct ccaccctcag ccagctcacc actcacagaa cagacctgaa     1560

tccgattctt taaaatgcac catcagacct ggcctccaag aagagctgta gcgtaccatg     1620

cgtcctttct tttaagggca tttttagaat taactcagac ctggaagact cctcagttct     1680

tcaaagactg gctttcattt ttatagttat tatggaaatg ttgtctttta tacttagtta     1740

tataagaaaa aagggagtta tgcaattaat atctatcagc ttgggaaacg ctttggtgct     1800

tttctccagt tttctggtac cagttacttg tttataaact gaaccttttc tgtatatagc     1860

catggtttca ttcttatcag tccaaccctt tgcctgaaac attgaatctt gttaaaccac     1920

agcttttagc taaaatgagg tatacctaga tgtcaagtaa gacagatcca aggtaactgg     1980

gtaggaaatc ttttgacatc ttaactcatg ttgagtttgt gctgtggtgt caccagaatt     2040

ccagataaac acacagcctt tcccatacct ttttttttct tactataaaa tattataaga     2100

tccattgatg tccaaataat accaccaagc atctcttcac ctctcctcct cttggtccac     2160

ttgctaatgc ccagttttct tctccatttc cactttttct taggctccct atttactatt     2220

cattttgact tccttctgtt ttattttttt ccctttagca ttgcatgtga ataagaaaat     2280

aatgtttaaa gaaaaaaaaa aaaaagcaaa cctccaaaac gtggacctaa ccattgcttc     2340

acttacactt cacccacagc tggagttcat tcaactcttg cttttcacaa aatagtaacc     2400

aggagatgtt taatgtgcct gatttaatgt ttttaataat cacagcaaat gaaaggtggt     2460

ttagttataa gtgaagcatg gttgaatacc agctggggag acactaggga agggagcttt     2520

gtaagccttg attgcgaaag tccaaatttt gatgtggggc tataacatga cacccttgga     2580

ttgcgactgg ttttatacgg cctgcctata acgttgaaaa tccatgtact acataataat     2640

tcagaagggc tctattcact acacagatta cattgttcaa tcatcagctg ctaatagcct     2700

aagatttatt tttttttttt tcttaagcct atggaaccgg ctttgctgtt ctggggggtg     2760

aaaatagact aactactgga gaaacaaaga gagaaagaaa acccagtgtt tccatagggg     2820

cacttttagc cttcccacaa cagttaagca ctctttgact gctgaaggaa ccccatggat     2880

gaggtgcagg ctacttcact cttttttttt cttttttgag acagagtctc acctattgcc     2940

cagactgaag tgcagtggtg cgatcatgga tcactgcagc agcatcctcc gagttcaagc     3000

tatccttcca cctccgcctc ctgagtagct gggaccacag gttcacataa ccatgcctgg     3060

ctaatttatt tttactttta ttttaaaata aaagatgagg tctgtcttat gttgcccagg     3120

ctggtctcaa actatcctac ttcttcctcc caaagtgttg ggattatagg tgtgagccac     3180

tgcacccagc ctacttcact cttctgaatt attctgattt attttcaaca acttttgtga     3240

acttgcccgt gatacaaagc agatagtccc tgaaccacag tcgtgcctcc ttgaaacaag     3300

ccattctact gtgctaatgt tttaatatca catctcacaa ataacagggg tgaatgtttc     3360

tctctagcaa tctaggcagg tgctggtgtt tcatctccat ttgaatgctt gacctcttaa     3420

tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgttcatggg ttttaaaaga acagtatttt     3480

acaaaaggtg tagcttttat aagagtgcag aaaagggaag gatgtgtttt tttctctcac     3540

tatagtataa gaatctattt tggagaaaaa aagaaaatat gagggtctcg aagcatgatt     3600

tttatataac tagtttcagt tttatctaat aacttacttt ttaaatcaat atttatcaac     3660

aatctttcct tgtatgcagt gctttcaaaa gatggttttg agtgtccagt gaaacttatg     3720

acttggatat atggttgaag aatcaaaaca aaagcaaaaa aaaaaagcaa aaaaagaaaa     3780

gagaaaaaaa gaaaaaatgc aaatggaata attttctatt atattttaga caaacatatc     3840

attttcgagt attttaaata ctgaattcat agttgttgtt ttttaaattc caacagtaac     3900

agctgaatgg tttaatctga ctggcttcct aagaaatgtt taagactcag ctttaaaaag     3960

aagttaacat tcatatctct gttttgaaat caaaaatcat atttcaaaat tctttcctag     4020

gaccatctat gtgtctcccc tcccctccac aaaaaggaga aagagtgcat taaaatgttt     4080

agttgggttt tttaattttt aatttttatg ttatgttttg ctttgtttta agtaaacaaa     4140

aatttttctt tctttactgc atgcatagca cttaataaaa tggattttta aaaaatccac     4200

tagtaatatc agaatgtcca gggagtgact gtcactacaa tgatggttta gtttacttct     4260

gttccacctt ttgattgaaa tatttagttg ttaggctgaa agcctcggca gttaagaact     4320

tgcctgagtt ttcttcgttc agcaacttga cagtttgact gatgtgcatt atatatagct     4380

caattatgtc tgttttttat gctaagtagg aaaaccaacc acacacatta gcaaaccggc     4440

ctcaacatat aattagaata aactgtcttc ttgttctact cagggccttt aggtgtgttc     4500

attcacggta tggaaataca gtaaatgaaa gattccaact agttgtcagt gcttcttgaa     4560

attccaaaca gaaagataca ttggtcaaat ccaacacttg gcttatcaat attaagtctt     4620

ttacctaaag gcccagccgt caccagacaa cagaataatc aatctgcctg aaaatccctc     4680

ctccttgtcc tacacttttt gcctgtttgg gagaatatct ttgtactcca ttctcctccc     4740

tcagccagtt actgggtcac ccatccatgt gttcatgaat caatcatcac ggcctgcaga     4800

gcacctgtcc taaggaggga aaatcctgtc acactgcctc tccccattcg tgtgtggttt     4860

tcttgatcgg tgagatctgt ctctgaagtc actgccagcc tccctgggaa cgtctatagt     4920

gcctcccctg ccttatgtga tgggagttaa caactcagat aagtacacct gagagcattt     4980

ctatcaggta aactgtcact taaatggagg tgtccacatc ttaattgttt ctccttgaca     5040

catttctcaa tccacgaagc caggagaggt agagtgaaaa tcccagccat ggatgaatgt     5100

actaatttga aagccaagtg ttaagtcgga tgttttcccg ttacactact actcagccct     5160

ctcctgcggc cacatcaacg gatgcaagtc acagtcttaa cacagcctgt gggagacaag     5220

cagtttgtgt gctcacagta tatattatag taattagggt gacttagagc aaatactctt     5280

cagatcctat gtagtcagtg aaacaaaatg gagagcgtat tctgatagaa ggacgtcgac     5340

ggtgaatgtt ctggtggttg ttgcctgtta agtaaacttt agtgtgtaag ttgagtttgt     5400

cattaaaatc ataaaccagc tgcggtaaca gacaagcctt tggctgggga gttttaagcc     5460

tcggtaactg ctataaaact agccatccag ttaggataga atgtgtttct ttctggttaa     5520

aaaaaggaaa aaccatctaa gaaaatatat atgtatgtat gtgtgtatac agtggaattc     5580

aaaggaccaa agcaaaattt gaacaggaat ctattaattt agaattttat aagatattta     5640

ttaataaatg ttatttttaa acattccatt tgaacagtat tctgtaggat ctacttgttt     5700

ttaaagtgtt agtccataat aaactactat agttatgtgt attttcattt ttcagggttt     5760

caaatggcta ttctccatca tttggtggaa atgtttgctt agatctctgt gcatagacat     5820

ttcaaggatt tttattgctc tgtgagttat tttttaatca acattctgaa cagttttttt     5880

taaacattta tttctgtgtg ttcattttta aagtaagctc tttcatttag gaagcagagt     5940

tcagctaaag ggaatcagta actctaactg gaacagcttt cttgtagaag tgtaaaaaca     6000

gcttcatctc tgcctctctc caccccaccc caatttccta gaaagccttg cactattcag     6060

ctcccttagt gctttttgtc ccttcccgaa caatatgcag tagctttaag ccattcaagc     6120

tccattatgc agtatatctg agaagggaaa ggaaacaacc catttaaatt tgaataaaac     6180

cgtgcctatg cgaacagtag caatttagaa tctcttttct gcttttaaaa taatttatat     6240

ttaaaaattg cactttagct ttttgatccc tttgtatttc tcttattctc tttctaacct     6300

cttctctgtc ctcaaacttg cctttgctct cctttacaat accccccacc cctcctccaa     6360

ggctctgagc ggcatcattt aaaatacttt acagatattt gcaccaggta catttatgtg     6420

cgtccattgg tagcacagct gagacctgtg tctcacatca gcctaggtga agcctactac     6480

aagaatgcca aggagaagag ccagtacact atatggttta tactctttat ccctttattc     6540

atagcatgtt ttttaaaaat gttatattat gcaacagatg tgaggcagca gctaagctat     6600

acttaagaat tttctctcac cttccaaacc aaagtgtcct gaataagcca ggagacttat     6660

tcttttgtgc accctggtgc acatctgact gttgtcctag ccatagactc tctgaggcca     6720

ctgaaagaac agtggcccta tcgatttcat tcctaggtct caaaaataca atgttgcctt     6780

gtaacataat tagggacagc acctctattt cacaattata atctaaggta ggataagacg     6840

acacagcagc aataaactta caagtaaaat tcaataccaa aacaaacaca aagaaattta     6900

aaaaacaaaa aacctagctc atcatgttgt gaaaatgaaa aagtgaatgt ccattcaaaa     6960

tattttacta tttcttgtgg agtttttcag tgatgtaatg cttgtagcca aattgcttaa     7020

agagtgttta tatatttttt tccttataaa ttgtctattt tttaaaaaag ctatttaacc     7080

acagctgaag tggggggtaa ggccaaattg ccaacacttg ttaaaagatt aatactctta     7140

agtggcactc tgataccttt ccaacttgtc atcagaaagg aatcaataat taccaactgt     7200

tgtatttaga ccaacttaca atatctagct cattagaagc caggatctag aaagctcctt     7260

ctaagccatt taagatattc ttacattgag cttcatatta tagaacttta taggattgga     7320

tattttacaa tagaataatt tagcctcagg actgagaatg tggaagctga ataaattagc     7380

tttaaataca tcattaaaat cttatgcaca ataagctcat tagattctag ttttctcctt     7440

tagaatacca atgccacaga cactacagga gataatgaaa ggtatcagtt gtgttgagtg     7500

gagggagttt aagagaaagg acccttccca accagcagcc agtagaaaat acaacctact     7560

cacctttttc ccttctaagt tctgctaaat cacatctgcc tcatagagaa aggaatgttg     7620

cctttgagaa ctgtcttgga gaacagataa gcttgaaatg ttctctctag agaggacata     7680

gggtttggga tcctctgaaa aggcccagaa aaatagctca gttcaaatac aatgttctag     7740

gacaattgga atataaatat tgtccaaaaa tataattaaa agaaaaaagt ttagcactgt     7800

gtaaagtaag tgttaactga ggaagtccca aaaaggtgct gtcactttaa gttctggact     7860

tggggttctt tgtatttgta aacagcaaag catttgtgtt tgtttgtcta tttgtaaagc     7920

aaccaccttc cttattggaa ggagaaaaaa aggggtacat acatgtaaat acttgctgca     7980

gcatttaata tgtttaattt tgtgttaagc tttttgttgc atcgtgaaca catttattgt     8040

taccaatgga caatgagttc attaagactg ttcaactagg tcagattttt acatctcttt     8100

ctagcaagaa gagacaagat tttgtgcatt tgtacaaatg ttaatatcac tgcaattcca     8160

atataataaa gcactcaaat gcaaataaaa aaaaaaaaaa aaaaaaaaaa                8210


<210>  1963
<211>  4251
<212>  DNA
<213>  homo sapiens

<400>  1963
ctctctatca atatcagctc acatcattga aaagataatt ttgaagacat gttttgctga       60

aaagacacta agaaaaattt tacgaatggg atgaacatgc tccagttaat tgactaccta      120

ctgcaatttg aatgttaaca ttacccatct ggtacagtta cctagtgatg tacctatttt      180

cacaataccc tgtttcagtg tgcttgtctt gattaaagaa ttcaaagtgg agtaccgcaa      240

acttgatatg gaaaataaaa agaaagacaa ggacaaatca gatgatagaa tggcacgacc      300

tagtggtcga tcgggacaca acactcgagg aactgggtct tcatcgtctg gagttttaat      360

ggttggacct aactttagag ttggaaaaaa aattggatgt ggcaattttg gagaattacg      420

attagggaaa aatttataca caaatgaata tgtggcaatt aagttggagc ccatgaaatc      480

aagagcacca cagctacatt tggaatacag attctataag cagttaggat ctggagatgg      540

tatacctcaa gtttactatt tcggcccttg tggtaaatac aatgctatgg tgctggaact      600

gctgggacct agtttggaag acttgtttga cttgtgtgac agaacatttt ctcttaaaac      660

agttctcatg atagctatac aactgatttc tcgcatggaa tatgtccatt caaagaactt      720

gatatacaga gatgtaaaac ctgagaactt cttaatagga cgaccaggaa acaaaaccca      780

gcaagttatt cacattatag attttggttt ggcaaaggaa tatattgatc cggagacaaa      840

gaaacacata ccatacagag aacacaagag ccttacagga acagctagat atatgagcat      900

aaacacacat ttaggaaaag aacaaagtag aagagacgat ttagaagctt taggtcatat      960

gttcatgtat tttctgagag gcagtcttcc ttggcaaggc ttaaaggctg acacattaaa     1020

ggagaggtat cagaaaattg gagatacaaa acgggctaca ccaatagaag tgttatgtga     1080

aaattttcca gaaatggcaa catatcttcg ttatgtaaga aggctagatt tttttgaaaa     1140

accagactat gactacttaa gaaagctttt tactgacttg tttgatcgaa aaggatatat     1200

gtttgattat gaatatgact ggattggtaa acagttgcct actccagtgg gtgcagttca     1260

gcaagatcct gctctgtcat caaacagaga agcacatcaa cacagagata agatgcaaca     1320

atccaaaaac cagtcggcag accacagggc agcttgggac tcccagcagg caaatcccca     1380

ccatttgaga gctcaccttg cagcagacag acatggtggc tcggtacagg ttgtaagttc     1440

tacaaatgga gagttaaaca cagatgaccc caccgcagga cgttcaaatg cacccatcac     1500

agcccctact gaagtagaag tgatggatga aaccaagtgc tgctgttttt tcaaacgaag     1560

gaaaaggaaa accatacagc gccacaaatg actctggaca cagacagatc ctggggagtt     1620

acttacatgt tcatctgctg tcttgtgatt aaaatcatct ctgtagtgac cacgtatatt     1680

ttcaaggact cactcttaga aacaaaaatg tcatactttc atacttcatt ttgtggttgt     1740

cttacattct ttttcttttt ttttttttct ctaatttaac ctttatggaa gctttaaagt     1800

tttgtcaaaa catgagtgct ttgcccatca gtgaatggaa tggaccaatg aggtggtatc     1860

aatgaatata gttccataga acattttcca gaagttcttc tgttgtagaa agcagtacag     1920

tatcttaagt gtcaaccagt tatataccta atctggtttt ttataacttc tgtaagagca     1980

taatcaaaca ggaattttct tttctcagtg gataatacaa cagagaaaac agagttgccc     2040

aaatatttaa aagaagttat tccttgagaa gttcatattt tgtgacatct gcattgattt     2100

cagtattact gatggtactg ttattcataa gtcatattaa cattctctcc gtgaaatcat     2160

ggtacagtca ctgcccagag gtactgagga aaaagcaata tgggttcggc agatggtggt     2220

ggtaaaatga atcttaagga gtgtggtaaa tatgtgctcc gcttttgttg catcactatg     2280

tgaagtactg tgttgcagaa gtggcaaaag cgcttatttt taaaaatgca aaatatttgt     2340

acaatgtaac tttatgcttc caaataataa tgtatgttag acagcaagaa atgaatactt     2400

taaaaagtga tgtatgttgg agttataaag aaatacacta aggagaggta gtaaatgtga     2460

accttgttgc agtgtataag gtggaagcct aaagaaatct caccgaaact tactgctgaa     2520

tgattacatt ctcccttaag cagaaaactt tggatgtgcc atgcaatggt gtctgtgtaa     2580

ttattttgct ctttgattaa aaaaaagacc cccagcaata aaaagtgggt cactctatgc     2640

cctctgtgca cattagtctc ttgtattcaa ctttgctgat tctctggaat tttcctactc     2700

tttagcataa ttttgatgat tgaaaaatat tttggaaagg atgggtcagg tgctttgcct     2760

ccatagtctt ttgaagtgcc tgcatatgaa caacaacaac aacaacaaaa aattctgtaa     2820

aaaaggaagc ccattccact tttcaagtat gctttgtttt aagccataaa gacacacatg     2880

tagttttgtc acattctact agccaaaatt ttcaagaagg gttaaaacaa agactggcta     2940

gaaagataat tattttgaat aaatctcata ttcatctttc atttatataa ttgttactta     3000

ttcctcccat gcagtctctt cgttgtcttt aagtgtgtgc ctccaggcat gcttatttat     3060

ttttattgtc tcaaggtaac atttaagatg tatattaaag taaagctaca tttttttact     3120

tcattattgc atttacaggg atttaattgt actttgtaat ttatttttct tattagccaa     3180

aagtttaatg catttttttt tgatgaatta ggcacccaca tgaacaccac aaatcaggac     3240

attgtttatc attgttgcta tgaatcctat gaatgatctt ttttttattt taaagaccta     3300

cacttaacct acaaaacatt tgctgtataa tttggtcaac agtttctatc tatctgtata     3360

ctgtcatgat gtcttaaact gcaggagtta catactgagt ttatattttt atttgctttg     3420

agcaaggtag ataaacattt tggccattat aatgtgaaac cacttcttct ttctttacag     3480

tatttgacca aacttgtgtg tctatgatat ttgtaaatac atgcgaatat ctgtatttct     3540

tatcataagc ctatttagtt ttattctcag tagggttttt tggattgtac agtgtttata     3600

tgatctgaac tccttataca taagaaggtg tgtatattaa tccaattatg gacttaaaat     3660

attttaaaag tataaatacc cttatttgct gcaaagacca gtgtgtaggc atttgctttt     3720

tagcaatatt tttaagtgct ccattttaat gccgaggaat aagtcttttg gcaacacaaa     3780

ctggtcaata ataggtaatg caggtatgtt caggttaagc caacaatgtt ttgcattttt     3840

atgcttattt tctgtcaaca ctaatgaagt caacattgcc tgaatgtctg aataatgaaa     3900

cacatccctg tttaaaagta tgtaactgaa aaagaaataa aaaaaaataa aagtagtttt     3960

tttaaacttg ctctttccca tttcctctaa agatgggtaa aataatgtca ctccctaatt     4020

taagatagga attataaaaa tttggtttat ttagtctgtt atatatgaga agcagagcta     4080

aaggaatatg cttttgttat tttatgtttt gttttgcttt cttgaaatcc agtggtaaaa     4140

agcacacact aggaaggatc taagctttct ttaatataaa aaaaattata cttctctgaa     4200

ctgtttaata gagcaataat taaatacatc ttctgataaa aaaaaaaaaa a              4251


<210>  1964
<211>  8532
<212>  DNA
<213>  homo sapiens

<400>  1964
cgggatggca actgcggtca ccctgctaaa gtcggggcgg gggcggcggt cctccccctc       60

acccccccca gtccgagcgc cgccgccgcc gccgccgccg ccgccgcggc cgctcagtaa      120

cacgtcccca ggagactcgc aggagcaaca cgtgatgtgt ctacttatca gggttgctcc      180

gactgtgtgt tccaggagtg gtggctctga ggtgtgaccc tgcccacgtt tgggcccagc      240

caggttcagc cccccaataa ggagggcagc ttgataacac aaagaaaaca gtgtcaacga      300

gtactaccaa gagaagaaga caagaggtca acacagactc attttctact ccgtgtgaat      360

gatagctaca gcaggggaaa gtttcatagt ctatcagtgg gtcagaaaat ggagttttat      420

agcagaggct tcttagaagc ttaaacccct gtcccaatga cgtcaagttc gcccgctggc      480

ttggaaggtt cagacctatc ttccatcaac accatgatgt cggcggtcat gagtgtaggg      540

aaggtcacag agaatggcgg gagcccccag gggatcaagt ccccctcgaa gcctccagga      600

ccaaatcgga ttggcagaag gaaccaggaa acgaaagagg agaagtcttc ctataactgc      660

cccctgtgtg agaagatttg cactacccag caccagctga ccatgcacat tcgccagcac      720

aacacagaca ctggaggagc cgaccactca tgcagcatct gcggaaagtc actgagctcg      780

gccagctccc tcgatcgcca catgctggtg cactctggcg agaggcctta caagtgcact      840

gtgtgtggcc agtcatttac caccaatggg aacatgcaca gacatatgaa gatccatgag      900

aaggacccta acagtgccac agccacagcc cctccatctc ctctgaaacg taggcgattg      960

tcctccaaga ggaaactgag tcacgatgcc gagtcagaga gagaagaccc agcaccagct     1020

aaaaagatgg tagaagacgg gcagtcaggt gacttggaga agaaagctga tgaagtcttt     1080

cactgcccag tatgtttcaa ggagtttgtt tgcaagtatg gactggagac ccacatggag     1140

acccattcag ataacccact aagatgtgac atttgttgtg tcacctttcg aacacatcga     1200

ggactgctgc gtcacaacgc gcttgtccac aaacaacttc ccagggatgc aatgggcaga     1260

cctttcatac agaacaaccc ttcaattcct gctggcttcc acgacttagg attcacggac     1320

ttctcctgta ggaagtttcc tcgcatttct caggcctggt gcgaaacaaa cctgcggagg     1380

tgcatcagcg agcaacaccg ttttgtctgc gacacctgtg acaaggcgtt ccccatgctc     1440

tgctcactgg ctctgcacaa gcagacccat gtggcggcag accagggtca agaaaagccg     1500

caggccacgc ccctgcctgg tgacgccctg gaccagaagg gcttcctggc cttgcttggc     1560

ctgcagcaca ccaaagacgt caggcctgcc cccgccgagg agcccctgcc ggatgacaac     1620

caggcaattc agctccagac actcaagtgt cagctacctc aggaccccgg ctgcaccaac     1680

ctgctgagcc tgtcaccttt cgaagctgct tccctaggcg gttctctcac agttctcccc     1740

gcgaccaagg acagcataaa gcacctgtcc ctgcagccct tccagaaggg cttcatcatc     1800

cagcctgaca gcagcattgt ggtcaagccc atctctggcg agtcggccat cgagctggca     1860

gacatccagc aaattctgaa gatggcagcc tcggctcccc ctcagatcag tcttccgccc     1920

ttctccaagg cccctgccgc cccactgcag gcgatcttca agcacatgcc ccctctgaag     1980

ccaaagcccc tggtcacacc acggacggtg gtggccacct ccacgccccc gcctctcatc     2040

aacgcccagc aggcttcccc gggctgtatc agccccagcc tgccgccacc gcccctgaag     2100

ctcctcaaag gctcagtgga ggcggcctcc aacgcccacc tgctgcagtc caagtccggg     2160

acccagcccc acgcggccac gcggctctcc ctgcagcagc cgcgggcgga gctgccgggc     2220

cagcctgaga tgaagacgca gctggagcag gacagcatca tcgaggccct gctgccgctg     2280

agcatggagg ccaagatcaa gcaggagatc acagaggggg aactcaaggc cttcatgaca     2340

gcgcccggcg gcaagaagac gcccgccatg cgcaaggtgc tctacccctg ccgcttctgc     2400

aaccaggtgt ttgccttctc gggggtcttg cgtgcccacg tgcgctccca cctgggcatc     2460

tcgccatacc agtgcaacat ctgcgactac atcgccgccg acaaggccgc gctcatccgc     2520

cacctgcgca cgcacagtgg ggagcggccc tacatttgca agatctgcca ctaccccttc     2580

actgtcaaag ccaactgcga gcggcacctg cgcaagaagc acctcaaggc cacccgcaag     2640

gatatcgaga agaacatcga gtatgtgagt agcagcgcgg ccgagctggt ggacgccttc     2700

tgcgccccgg acaccgtgtg ccggctgtgc ggcgaggacc tcaagcacta tcgtgccctg     2760

cgcatccaca tgcgcacgca ctgcggccgc ggcctgggcg ggggccacaa gggccgcaag     2820

cccttcgagt gcaaggagtg cagcgccgcg ttcgcggcca agcgcaactg catccaccac     2880

atcctcaagc agcacctgca cgtgcccgag caggacatcg agagctacgt gctggccgcc     2940

gacggcctgg gccccgcaga ggcgccggcc gctgaggcgt cggggcgcgg ggaggacagt     3000

ggctgcgctg cccttggtga ctgcaagccc ctcactgcct tcctggaacc ccagaacggc     3060

tttcttcaca ggggccccac ccagcctcca cctccccatg tctcgatcaa gttggagccc     3120

gccagtagct ttgcggtgga cttcaatgag cccctggact tctcgcagaa gggcctggcc     3180

ctggtccaag tgaagcagga aaacatctcc tttctgagcc cttcttccct ggtcccctat     3240

gactgctcca tggagcccat cgacctgtcc atccccaaga acttcaggaa aggggacaag     3300

gatttggcca ctcccagcga agccaagaag cctgaggagg aggcggggag cagcgagcag     3360

ccctctccct gcccagcacc cggcccttct cttcctgtaa ctttggggcc cagcggaatc     3420

ctggaaagcc ccatggcccc tgctccggcg gccaccccgg aacccccagc acagcccctg     3480

cagggccctg ttcagctggc ggtcccaatc tactcctcag ccctggtcag cagccctcca     3540

ctcgtgggca gctcagccct cctgagtggc acagccttgc tgcgtccact gcggcccaag     3600

cccccgctgc ttttgccaaa gccccccgtg acagaagagc tgcccccgct ggcctccatt     3660

gcccagatca tctcatctgt atcctcggcc cccaccctgc tgaaaaccaa ggtggcggac     3720

ccagggcccg caagcactgg cagtaacacc acggcttcag acagcttagg aggttctgtc     3780

cccaaagccg ccaccaccgc cacccccgct gccaccacca gcccaaaaga gtctagtgag     3840

cctcccgctc cagccagcag cccagaggct gcctctccca ccgagcaggg cccagcgggc     3900

acgtcgaaga agaggggccg gaaaaggggg atgaggagcc gaccccgcgc caacagcggc     3960

ggggtggacc tggactccag cggggagttt gccagcatcg agaagatgct ggccaccaca     4020

gacaccaaca agttcagtcc gtttctgcag acagcggagg acaacactca ggatgaggtg     4080

gccggagccc ctgccgacca ccatgggccc agtgatgaag agcagggcag tcccccagaa     4140

gacaagctgc tgagggccaa gcggaactcg tacaccaact gcctgcagaa gatcacctgt     4200

ccccactgtc cccgggtttt cccttgggcc agctccctac agaggcacat gctcacacac     4260

actgacagtc agtcggatgc ggagactgca gccgccgcgg gcgaagtgct agacctcacc     4320

tcacgggaca gagagcagcc gtcggagggc gccactgagc tccgccaggt cgcaggggat     4380

gcgcctgtgg agcaggccac ggcggaaacg gcctcgccgg tgcaccggga agagcacggg     4440

cgtggggaga gccatgagcc ggaggaggag catggcactg aggagagcac tggggacgcc     4500

gacggcgcgg aagaggacgc gtcgagcaac cagagcctgg acctggactt cgccaccaag     4560

ctcatggact tcaagctggc ggagggcgac ggcgaggcag gcgccggggg cgcggcctcg     4620

caggagcaga agctcgcctg cgacacctgt gggaagagct tcaagttcct gggcaccctg     4680

agccgccacc ggaaggcgca cggccgccag gagcccaagg acgagaaggg agatggcgcc     4740

agcactgcag aggaggggcc ccagcccgcc cctgaacagg aggagaagcc ccccgagacc     4800

ccggcagagg tggtggagtc ggccccgggt gccggggagg ccccggcgga aaagctcgcg     4860

gaggagacgg agggcccctc cgacggggag agcgcggccg agaaaaggtc ctcagagaag     4920

agcgacgatg acaagaaacc aaagacagac tcccccaaaa gcgtggccag caaggcagac     4980

aagaggaaga aggtctgcag cgtgtgcaac aagcggttct ggtcgctgca ggacctgacc     5040

cggcacatgc gctcccacac aggggaaagg ccatacaaat gtcagacctg cgagcgaacc     5100

ttcaccttga agcacagcct ggttcgccac cagcggatcc accagaaagc caggcatgcc     5160

aaacaccacg ggaaggacag cgacaaggaa gagcggggtg aggaggacag cgagaatgag     5220

tccacccaca gcggcaacaa cgccgtctca gagaacgagg ctgagctggc tcccaatgcc     5280

agcaaccaca tggctgtcac ccggagccgg aaggagggct tggccagtgc caccaaggac     5340

tgcagccaca gggaggagaa ggtcacggca gggtggccgt ctgagcctgg ccagggtgac     5400

cttaacccag agagcccggc ggccctgggg caggacctgc tggagccgcg cagcaagagg     5460

cctgcccacc caatcctggc cacagctgat ggcgcctccc agctcgtggg gatggagtga     5520

cagcctcagt ccccctcagc acagacaaaa gccagcagag caaagcgtct atacttcatg     5580

gggtttcctc agtgcccttt ggctgttgag gagtgagaga gagagagaga gagagagaga     5640

gagagagaga gagagacaag caggagcgtg gctgctcgct cagtgccata gccttaccgc     5700

agcctgcgcg ggaggccaca gcccgtgccg attccagtgc cttaactact taccggatcc     5760

ctccatatta tcatgggtgt tgtatttttc caaaatgact tcttaaacaa aacaaatatt     5820

ataatgaatt gtctggagag gacctcttca tttgagcatt agcgttattt tgtattggtg     5880

tgtgtgagct tgttcttgtg aatctgtgat agcaccgttt gttctgtgag ctggaaacag     5940

aaggaaaaaa catacccttg ggtacccata gccaataact ggaagaaaat gatgtgaatt     6000

tcatgtaaat gaccagagga aagatggata agatgataat ttcttaaata gacattttcc     6060

ttttttcttt gtgcttcatg gtggagctgt catctggtcc ttggtattac aggatgtggt     6120

tgatgaaggt ttccaatatg gtttcaggcc aaaaccaggg aagattctag cttcagcctc     6180

atgtccattt ccagtctgtc agcattagac atggtcactg ttcaagtttc aagacatcca     6240

ttcttaacta tagagaagag ttactcccct ggcgtcttaa cctatggaaa acatgcacgg     6300

ataggatata tttgattgcc tcctcttccc tttcagtata tgtattatta atattattat     6360

tattattatt attattagtt catcagtttg ctgttctctg cagtgagcag aatcaaatgg     6420

gcaatatttg tcctgggaga cctgtgccgc acccaggtcc ccgtgttaac gtgtgcctgc     6480

ggttgtggtt ggcaccctcg ggtggtagct cttctactgt aatgagacaa gcctttcttc     6540

tgtcactgca gaatttagaa ggggccgtga gcagtcttcc caagcatggt ccaggagcag     6600

ctcagagagg gtggagtgag gatgcatgca tccagggaac aggcatcaag aagccagggc     6660

cgtgcctgga gcactgcaga gatgactttg gagaaagcaa agcagtgacc cagtgaccag     6720

gcacattact cgtgagcgag gtattcccag tcttcctgct aagcctaatc caagccttac     6780

ccagctgtgc tactgtcatt tgcaaagcaa ggaaatacta ctactggtaa taaaactaca     6840

catgcaagat gtcagataag aaataggttt atatttacct tcctgcgatg tggggttggt     6900

gcttgaagat aaatgtgctg tttctagttt cttaaatagc ccacacccct ggatgcaaaa     6960

aggcagggtt atttttaccc atgagcatcc tgtgcaggca atagacttcc ctcactgtct     7020

ccgcctgcag ggaggagaat gtaccccact gcacctgagc tcctggtccc tcagccaaga     7080

cctcaggggt ccccagccag cctgctgctg gggacccctg tgcttgctgc agtgtatgga     7140

gcctcttgcc ttcccctggg gaggcacccc tgtaccccag cttccttccc ctggcctttt     7200

ctggccccag tgctcctcct ttacatagac ttgttcacac agaaacgtgc acgccccctt     7260

ttctccgcca cttcaccagt ttctgaaatc caacctccca gacttcacag gaagatagat     7320

attcttgaga taatgaaaag tgatatcttc gcatacgaaa ggaaaaaagg ttgaggtata     7380

tatgattttt aactgtatta ggggtgtatg aaccagttta aaaacgaggt tttatttact     7440

gtagagatga atgcaaatca gaaccaatga tcccttggcc tacttagtta aaaccagttc     7500

atacatccct tagggttttt attattatta ttattattat tacagttgtt attgttgttt     7560

ttgttgttat tattatttgg ggtttcttgt gttttttctt tgcgactctc cacactaaac     7620

ttgcaatatt gtggggagaa gctgtgacta aactctacgc tgcggtgaga tgtagcagta     7680

atcagctccc agcgacgtgt gtagctgggg ctgccgctcg caataatcac tattgattta     7740

aagctttact tagccttgat ctgtaccctc gtagtcaata aggtcttgcc acattttatt     7800

agtgaggtgg agaaacgtat tatttgtttg ttgtttttgc ccttccccca ccccccaata     7860

ttaaactgtg aaatttgtga tttgtttaaa ctctgggtga atcatagctt agtttgcatg     7920

tccagctaat ttgtttctat acattttgtt tgattctctt tctccttctc tcagggcttt     7980

tacaaaaaaa tatatatata tggatcttct gaaaagtttt ttgaggtgca agttttttct     8040

cttttttttt tttttttttt tttctcattg attaatggac atgatgctga gattcaatca     8100

ctacatgaaa cacctggctg tgaaaacaaa acaacccaga gggctgtgtt ccaagcagcg     8160

ctggggaagc tacgtaacag tcggatgcca gttttggaag attcaccatg cgttctgacc     8220

ctctgttcgt ctctttcctc tcctctttct tcaagaagga aattgatcct agtgatttca     8280

gcccatgcat taaacaggaa acaataataa atttgtagaa ttcatatttt tctaaaggga     8340

acttaaaaac tgctgctaca tgttatgtac aaaactggtt tatgccacat gaacagagaa     8400

tcacaagttt ggttttggta ctttttgttc ctctttgtat tcagttgtat agaacttcca     8460

aattcagaat gagaagaaag ctgttctgta tcaaaccatt taagcaataa atgttatatt     8520

ttaaaagctg ca                                                         8532


<210>  1965
<211>  7935
<212>  DNA
<213>  homo sapiens

<400>  1965
gcgccggggt cgccagctcc tcgcccacct ccctccctgt gggagaagag gaggagggga       60

agtgactgcg gagttgatga actttgcaca tccagaaacg ccattttgat tccttttccg      120

gaacaagttt gcatctctcc tcggtctctc cctgaagccc accggtcccc aacgcatcat      180

gccagggagc caagcgtcct gcccggccgt tgctccgact gtgtgttcca ggagtggtgg      240

ctctgaggtg tgaccctgcc cacgtttggg cccagccagg ttcagccccc caataaggag      300

ggcagcttga taacacaaag aaaacagtgt caacgagtac taccaagaga agaagacaag      360

aggtcaacac agactcattt tctactccgt gtgaatgata gctacagcag gggaaagttt      420

catagtctat cagtgggtca gaaaatggag ttttatagca gaggcttctt agaagcttaa      480

acccctgtcc caatgacgtc aagttcgccc gctggcttgg aaggttcaga cctatcttcc      540

atcaacacca tgatgtcggc ggtcatgagt gtagggaagg tcacagagaa tggcgggagc      600

ccccagggga tcaagtcccc ctcgaagcct ccaggaccaa atcggattgg cagaaggaac      660

caggaaacga aagaggagaa gtcttcctat aactgccccc tgtgtgagaa gatttgcact      720

acccagcacc agctgaccat gcacattcgc cagcacaaca cagacactgg aggagccgac      780

cactcatgca gcatctgcgg aaagtcactg agctcggcca gctccctcga tcgccacatg      840

ctggtgcact ctggcgagag gccttacaag tgcactgtgt gtggccagtc atttaccacc      900

aatgggaaca tgcacagaca tatgaagatc catgagaagg accctaacag tgccacagcc      960

acagcccctc catctcctct gaaacgtagg cgattgtcct ccaagaggaa actgagtcac     1020

gatgccgagt cagagagaga agacccagca ccagctaaaa agatggtaga agacgggcag     1080

tcaggtgact tggagaagaa agctgatgaa gtctttcact gcccagtatg tttcaaggag     1140

tttgtttgca agtatggact ggagacccac atggagaccc attcagataa cccactaaga     1200

tgtgacattt gttgtgtcac ctttcgaaca catcgaggac tgctgcgtca caacgcgctt     1260

gtccacaaac aacttcccag ggatgcaatg ggcagacctt tcatacagaa caacccttca     1320

attcctgctg gcttccacga cttaggattc acggacttct cctgtaggaa gtttcctcgc     1380

atttctcagg cctggtgcga aacaaacctg cggaggtgca tcagcgagca acaccgtttt     1440

gtctgcgaca cctgtgacaa ggcgttcccc atgctctgct cactggctct gcacaagcag     1500

acccatgtgg cggcagacca gggtcaagaa aagccgcagg ccacgcccct gcctggtgac     1560

gccctggacc agaagggctt cctggccttg cttggcctgc agcacaccaa agacgtcagg     1620

cctgcccccg ccgaggagcc cctgccggat gacaaccagg caattcagct ccagacactc     1680

aagtgtcagc tacctcagga ccccggctgc accaacctgc tgagcctgtc acctttcgaa     1740

gctgcttccc taggcggttc tctcacagtt ctccccgcga ccaaggacag cataaagcac     1800

ctgtccctgc agcccttcca gaagggcttc atcatccagc ctgacagcag cattgtggtc     1860

aagcccatct ctggcgagtc ggccatcgag ctggcagaca tccagcaaat tctgaagatg     1920

gcagcctcgg ctccccctca gatcagtctt ccgcccttct ccaaggcccc tgccgcccca     1980

ctgcaggcga tcttcaagca catgccccct ctgaagccaa agcccctggt cacaccacgg     2040

acggtggtgg ccacctccac gcccccgcct ctcatcaacg cccagcaggc ttccccgggc     2100

tgtatcagcc ccagcctgcc gccaccgccc ctgaagctcc tcaaaggctc agtggaggcg     2160

gcctccaacg cccacctgct gcagtccaag tccgggaccc agccccacgc ggccacgcgg     2220

ctctccctgc agcagccgcg ggcggagctg ccgggccagc ctgagatgaa gacgcagctg     2280

gagcaggaca gcatcatcga ggccctgctg ccgctgagca tggaggccaa gatcaagcag     2340

gagatcacag agggggaact caaggccttc atgacagcgc ccggcggcaa gaagacgccc     2400

gccatgcgca aggtgctcta cccctgccgc ttctgcaacc aggtgtttgc cttctcgggg     2460

gtcttgcgtg cccacgtgcg ctcccacctg ggcatctcgc cataccagtg caacatctgc     2520

gactacatcg ccgccgacaa ggccgcgctc atccgccacc tgcgcacgca cagtggggag     2580

cggccctaca tttgcaagat ctgccactac cccttcactg tcaaagccaa ctgcgagcgg     2640

cacctgcgca agaagcacct caaggccacc cgcaaggata tcgagaagaa catcgagtat     2700

gtgagtagca gcgcggccga gctggtggac gccttctgcg ccccggacac cgtgtgccgg     2760

ctgtgcggcg aggacctcaa gcactatcgt gccctgcgca tccacatgcg cacgcactgc     2820

ggccgcggcc tgggcggggg ccacaagggc cgcaagccct tcgagtgcaa ggagtgcagc     2880

gccgcgttcg cggccaagcg caactgcatc caccacatcc tcaagcagca cctgcacgtg     2940

cccgagcagg acatcgagag ctacgtgctg gccgccgacg gcctgggccc cgcagaggcg     3000

ccggccgctg aggcgtcggg gcgcggggag gacagtggct gcgctgccct tggtgactgc     3060

aagcccctca ctgccttcct ggaaccccag aacggctttc ttcacagggg ccccacccag     3120

cctccacctc cccatgtctc gatcaagttg gagcccgcca gtagctttgc ggtggacttc     3180

aatgagcccc tggacttctc gcagaagggc ctggccctgg tccaagtgaa gcaggaaaac     3240

atctcctttc tgagcccttc ttccctggtc ccctatgact gctccatgga gcccatcgac     3300

ctgtccatcc ccaagaactt caggaaaggg gacaaggatt tggccactcc cagcgaagcc     3360

aagaagcctg aggaggaggc ggggagcagc gagcagccct ctccctgccc agcacccggc     3420

ccttctcttc ctgtaacttt ggggcccagc ggaatcctgg aaagccccat ggcccctgct     3480

ccggcggcca ccccggaacc cccagcacag cccctgcagg gccctgttca gctggcggtc     3540

ccaatctact cctcagccct ggtcagcagc cctccactcg tgggcagctc agccctcctg     3600

agtggcacag ccttgctgcg tccactgcgg cccaagcccc cgctgctttt gccaaagccc     3660

cccgtgacag aagagctgcc cccgctggcc tccattgccc agatcatctc atctgtatcc     3720

tcggccccca ccctgctgaa aaccaaggtg gcggacccag ggcccgcaag cactggcagt     3780

aacaccacgg cttcagacag cttaggaggt tctgtcccca aagccgccac caccgccacc     3840

cccgctgcca ccaccagccc aaaagagtct agtgagcctc ccgctccagc cagcagccca     3900

gaggctgcct ctcccaccga gcagggccca gcgggcacgt cgaagaagag gggccggaaa     3960

agggggatga ggagccgacc ccgcgccaac agcggcgggg tggacctgga ctccagcggg     4020

gagtttgcca gcatcgagaa gatgctggcc accacagaca ccaacaagtt cagtccgttt     4080

ctgcagacag cggaggacaa cactcaggat gaggtggccg gagcccctgc cgaccaccat     4140

gggcccagtg atgaagagca gggcagtccc ccagaagaca agctgctgag ggccaagcgg     4200

aactcgtaca ccaactgcct gcagaagatc acctgtcccc actgtccccg ggttttccct     4260

tgggccagct ccctacagag gcacatgctc acacacactg gtcagaaacc cttcccttgt     4320

caaaaatgcg atgccttctt ttctaccaaa tctaactgtg aacgccacca gttgcgcaaa     4380

cacggagtta ccacctgttc cctgagaaga aacgggctta tcccccagtc aaaagagagt     4440

gatgttggat cccatgatag cacaggggaa aggccataca aatgtcagac ctgcgagcga     4500

accttcacct tgaagcacag cctggttcgc caccagcgga tccaccagaa agccaggcat     4560

gccaaacacc acgggaagga cagcgacaag gaagagcggg gtgaggagga cagcgagaat     4620

gagtccaccc acagcggcaa caacgccgtc tcagagaacg aggctgagct ggctcccaat     4680

gccagcaacc acatggctgt cacccggagc cggaaggagg gcttggccag tgccaccaag     4740

gactgcagcc acagggagga gaaggtcacg gcagggtggc cgtctgagcc tggccagggt     4800

gaccttaacc cagagagccc ggcggccctg gggcaggacc tgctggagcc gcgcagcaag     4860

aggcctgccc acccaatcct ggccacagct gatggcgcct cccagctcgt ggggatggag     4920

tgacagcctc agtccccctc agcacagaca aaagccagca gagcaaagcg tctatacttc     4980

atggggtttc ctcagtgccc tttggctgtt gaggagtgag agagagagag agagagagag     5040

agagagagag agagagagac aagcaggagc gtggctgctc gctcagtgcc atagccttac     5100

cgcagcctgc gcgggaggcc acagcccgtg ccgattccag tgccttaact acttaccgga     5160

tccctccata ttatcatggg tgttgtattt ttccaaaatg acttcttaaa caaaacaaat     5220

attataatga attgtctgga gaggacctct tcatttgagc attagcgtta ttttgtattg     5280

gtgtgtgtga gcttgttctt gtgaatctgt gatagcaccg tttgttctgt gagctggaaa     5340

cagaaggaaa aaacataccc ttgggtaccc atagccaata actggaagaa aatgatgtga     5400

atttcatgta aatgaccaga ggaaagatgg ataagatgat aatttcttaa atagacattt     5460

tccttttttc tttgtgcttc atggtggagc tgtcatctgg tccttggtat tacaggatgt     5520

ggttgatgaa ggtttccaat atggtttcag gccaaaacca gggaagattc tagcttcagc     5580

ctcatgtcca tttccagtct gtcagcatta gacatggtca ctgttcaagt ttcaagacat     5640

ccattcttaa ctatagagaa gagttactcc cctggcgtct taacctatgg aaaacatgca     5700

cggataggat atatttgatt gcctcctctt ccctttcagt atatgtatta ttaatattat     5760

tattattatt attattatta gttcatcagt ttgctgttct ctgcagtgag cagaatcaaa     5820

tgggcaatat ttgtcctggg agacctgtgc cgcacccagg tccccgtgtt aacgtgtgcc     5880

tgcggttgtg gttggcaccc tcgggtggta gctcttctac tgtaatgaga caagcctttc     5940

ttctgtcact gcagaattta gaaggggccg tgagcagtct tcccaagcat ggtccaggag     6000

cagctcagag agggtggagt gaggatgcat gcatccaggg aacaggcatc aagaagccag     6060

ggccgtgcct ggagcactgc agagatgact ttggagaaag caaagcagtg acccagtgac     6120

caggcacatt actcgtgagc gaggtattcc cagtcttcct gctaagccta atccaagcct     6180

tacccagctg tgctactgtc atttgcaaag caaggaaata ctactactgg taataaaact     6240

acacatgcaa gatgtcagat aagaaatagg tttatattta ccttcctgcg atgtggggtt     6300

ggtgcttgaa gataaatgtg ctgtttctag tttcttaaat agcccacacc cctggatgca     6360

aaaaggcagg gttattttta cccatgagca tcctgtgcag gcaatagact tccctcactg     6420

tctccgcctg cagggaggag aatgtacccc actgcacctg agctcctggt ccctcagcca     6480

agacctcagg ggtccccagc cagcctgctg ctggggaccc ctgtgcttgc tgcagtgtat     6540

ggagcctctt gccttcccct ggggaggcac ccctgtaccc cagcttcctt cccctggcct     6600

tttctggccc cagtgctcct cctttacata gacttgttca cacagaaacg tgcacgcccc     6660

cttttctccg ccacttcacc agtttctgaa atccaacctc ccagacttca caggaagata     6720

gatattcttg agataatgaa aagtgatatc ttcgcatacg aaaggaaaaa aggttgaggt     6780

atatatgatt tttaactgta ttaggggtgt atgaaccagt ttaaaaacga ggttttattt     6840

actgtagaga tgaatgcaaa tcagaaccaa tgatcccttg gcctacttag ttaaaaccag     6900

ttcatacatc ccttagggtt tttattatta ttattattat tattacagtt gttattgttg     6960

tttttgttgt tattattatt tggggtttct tgtgtttttt ctttgcgact ctccacacta     7020

aacttgcaat attgtgggga gaagctgtga ctaaactcta cgctgcggtg agatgtagca     7080

gtaatcagct cccagcgacg tgtgtagctg gggctgccgc tcgcaataat cactattgat     7140

ttaaagcttt acttagcctt gatctgtacc ctcgtagtca ataaggtctt gccacatttt     7200

attagtgagg tggagaaacg tattatttgt ttgttgtttt tgcccttccc ccacccccca     7260

atattaaact gtgaaatttg tgatttgttt aaactctggg tgaatcatag cttagtttgc     7320

atgtccagct aatttgtttc tatacatttt gtttgattct ctttctcctt ctctcagggc     7380

ttttacaaaa aaatatatat atatggatct tctgaaaagt tttttgaggt gcaagttttt     7440

tctctttttt tttttttttt ttttttctca ttgattaatg gacatgatgc tgagattcaa     7500

tcactacatg aaacacctgg ctgtgaaaac aaaacaaccc agagggctgt gttccaagca     7560

gcgctgggga agctacgtaa cagtcggatg ccagttttgg aagattcacc atgcgttctg     7620

accctctgtt cgtctctttc ctctcctctt tcttcaagaa ggaaattgat cctagtgatt     7680

tcagcccatg cattaaacag gaaacaataa taaatttgta gaattcatat ttttctaaag     7740

ggaacttaaa aactgctgct acatgttatg tacaaaactg gtttatgcca catgaacaga     7800

gaatcacaag tttggttttg gtactttttg ttcctctttg tattcagttg tatagaactt     7860

ccaaattcag aatgagaaga aagctgttct gtatcaaacc atttaagcaa taaatgttat     7920

attttaaaag ctgca                                                      7935


<210>  1966
<211>  5391
<212>  DNA
<213>  homo sapiens

<400>  1966
attggctgtg ggagccaccg tcccgcctcc cagcgactct cggcggtgcc ggagtcgggt       60

gggttggcgg ctataaagct ggtggcgaag gggaggcgcc gcggactgtc ctttcgtggc      120

tcactccctt tcctctgctg ccgctcggtc acgcttgctc tttcaccatg cctggatcac      180

ttcctttgaa tgcagaagct tgctggccaa aagatgtggg aattgttgcc cttgagatct      240

attttccttc tcaatatgtt gatcaagcag agttggaaaa atatgatggt gtagatgctg      300

gaaagtatac cattggcttg ggccaggcca agatgggctt ctgcacagat agagaagata      360

ttaactctct ttgcatgact gtggttcaga atcttatgga gagaaataac ctttcctatg      420

attgcattgg gcggctggaa gttggaacag agacaatcat cgacaaatca aagtctgtga      480

agactaattt gatgcagctg tttgaagagt ctgggaatac agatatagaa ggaatcgaca      540

caactaatgc atgctatgga ggcacagctg ctgtcttcaa tgctgttaac tggattgagt      600

ccagctcttg ggatggacgg tatgccctgg tagttgcagg agatattgct gtatatgcca      660

caggaaatgc tagacctaca ggtggagttg gagcagtagc tctgctaatt gggccaaatg      720

ctcctttaat ttttgaacga gggcttcgtg ggacacatat gcaacatgcc tatgattttt      780

acaagcctga tatgctatct gaatatccta tagtagatgg aaaactctcc atacagtgct      840

acctcagtgc attagaccgc tgctattctg tctactgcaa aaagatccat gcccagtggc      900

agaaagaggg aaatgataaa gattttacct tgaatgattt tggcttcatg atctttcact      960

caccatattg taaactggtt cagaaatctc tagctcggat gttgctgaat gacttcctta     1020

atgaccagaa tagagataaa aatagtatct atagtggcct ggaagccttt ggggatgtta     1080

aattagaaga cacctacttt gatagagatg tggagaaggc atttatgaag gctagctctg     1140

aactcttcag tcagaaaaca aaggcatctt tacttgtatc aaatcaaaat ggaaatatgt     1200

acacatcttc agtatatggt tcccttgcat ctgttctagc acagtactca cctcagcaat     1260

tagcagggaa gagaattgga gtgttttctt atggttctgg tttggctgcc actctgtact     1320

ctcttaaagt cacacaagat gctacaccgg ggtctgctct tgataaaata acagcaagtt     1380

tatgtgatct taaatcaagg cttgattcaa gaactggtgt ggcaccagat gtcttcgctg     1440

aaaacatgaa gctcagagag gacacccatc atttggtcaa ctatattccc cagggttcaa     1500

tagattcact ctttgaagga acgtggtact tagttagggt ggatgaaaag cacagaagaa     1560

cttacgctcg gcgtcccact ccaaatgatg acactttgga tgaaggagta ggacttgtgc     1620

attcaaacat agcaactgag catattccaa gccctgccaa gaaagtacca agactccctg     1680

ccacagcagc agaacctgaa gcagctgtca ttagtaatgg ggaacattaa gatactctgt     1740

gaggtgcaag acttcagggt ggggtgggca tggggtgggg gtatgggaac agttggagga     1800

atgggatatc tggggataat tttaaaggat tacatgttat gtaaattttt atgtgactga     1860

catggagcct ggatgactat cgtgtacttg ggaaagtctc tttgctctat ttgctgacat     1920

gcttcctgtt gtggtctggc caatgccaaa tgtactcgaa tgatgttaag ggctctgtaa     1980

aacttcatac ctctttggcc atttgtatgc atgatgtttg gtttttaaac atggtataat     2040

gaattgtgta cttctgtcag aagaaagcag aggtactaat ctccaattaa aaaatttttt     2100

aacatgtaag aattttgtac tttgaacaac aagattacag aaagtacctg tggtttttgg     2160

aaaacatttc tagcttgggg aatgtgacaa cattccccag tgtggtaaaa ttggggtaaa     2220

atgtggtaaa atgtgatacg cacaaaccct ttgaaaatag caaaacaaac atgccctttt     2280

tctaaaattg ataaatccta aagaggaaga aaagagctgg gacaataaaa cactggctct     2340

ggaatctgga atgttaagtc caggccagca gtgacaaaag ttattgtaat gacctctgaa     2400

cagagaaaca ctgccattga agaggcttct ggtatagaaa acatggtaca ttcaggagct     2460

gtgaatatag ctctaggtgt gctcctgaat cagttcatgg tagattatgc tgaacaacag     2520

tgagatgtta ttggaggtgt ggatgaggga gtttgttgtt gcagtccttc tttgcacctt     2580

attttaaaga ataaatgaaa catttttctg gttacttttt taaaaattta aaatggaagg     2640

gaagaatagg ggcagggcat tattaggcta tttctgatgc ttcagtgtta taaattcaac     2700

atagaggctg acaacctaaa ttcatggtgt aacacagctc ttttcctttt cctttttttt     2760

ttttttttgg tatctgttca atgaaaataa ggtatgaccc aagtttttac ctagtctgac     2820

tagaagtatt ccacttcaag gtctgaagta ggacttttac cttaaaaaac aacaacaaac     2880

aaaactatca cacaggatag ataagaagat tggttaaaca gttttgtgta gatctttttg     2940

gtgctgaact atgacatgag ccttatagat tgtaaaatag ggatagttgg aactaatgta     3000

cagaactaaa ttttttaaac tttatttgct gttaaattct gtgaagtttc agttatctaa     3060

aataaatata cacaaatatg aaatataatg tttcagattg caaggtaata tgtaatagta     3120

gtgtttgtaa gatactcttg tctaatatta actagtagta ttttgatttg tacagtcata     3180

atttgttaaa atgacttcat ttaacattca ctgatgtaga ttaataatgt aagttctgat     3240

ttaaagaatg gtggcaaaat ggtgcatgta atacttttgc aagtgttggg gagatcggta     3300

tgttttgaaa agagtaattt aacttttggg tgccaggaaa tgggttttct caaagtccat     3360

tgccggcaat gggcaggcct gcaaatactg gcacagagca ttaatcatac accttattaa     3420

cggtgaggtg aataactttg aaataaagtt ttagagaaat gtttcagata cttgagtatt     3480

ctttttcact cttgaactaa caacttcggc aagaaatcag ctaatattct atttttaaat     3540

atgggcatta atttcatttc agttcgttca ctcattccat tcatttatca tttcacaaac     3600

atttgaaatc ctaatataag caaggtgctc tgtttaaggc agaaatttga aaatgtacaa     3660

gatatatggt cttgtcttta aggagctgtt catctagaat ggaggaattt acactgataa     3720

ttattcctac acttgaaaca aagaaattaa ctctcaaatt gcgtggcaag catatataga     3780

ctttgctata aatatttatg aaatgagtta ctgttttcct taaaaaagct aagactaagg     3840

gctggcaatc aaataagagc aaatttagtg gtgaacgtag aactgcccac taccagctag     3900

agtctccaac ctaaaagtcc catgttgcta gtgatcccca ggggttttat agaaggaatc     3960

cctgcattgg cagtaatttt ggattagatg atccctaaga gcaccatcaa gtcttaggat     4020

tctatgaatt aggaaataaa ccaaattata tattttctaa tactgatcag ctcatatttt     4080

atcatcatgt catgtctggc tttcatactt agtcataatt tactttctgg gtcatttaga     4140

ggctagcgtt ctctaaggtc acttctgctt gcacattgta ggatattatt tagtatggct     4200

ttaagaattc aatctttccc cctctccttt atggaatgtg tgtttcctct atttgtacac     4260

ttaacctttt gtcctaagtt tttattttta tggatactaa tgagtaactt tgaggttgac     4320

actagaccca aacagatgca aacagccact ttctgtcctc ttgtgacaca gttgaaacac     4380

tttatctctt gtctgctgtt tggagtgtcc tgaaagaaac actgaagtgg cagtcaacag     4440

agcaagggta acaggatctt taaataattt aaagttgtct gatcttgaca taaaagtgaa     4500

ccctttcttt aaaatttcta gcaactgctc ttaagtcata ggttcctcat tttttctttg     4560

ctggtagtgg gagaaaatag ttgatctgtg atttttgttt tcatctcccc aaactatgtt     4620

ataaaggcag taatttgatg ctgaagatta tgattagaaa tcctcagatg ggttatatat     4680

tggggcttta tcttttaata ttaaaaagaa tgtctttcct ggactacttt attcagtagt     4740

aagcactatt cattctatgt atattcctta ttcagccttg cagactcctg tgggatctga     4800

tctcttcctg cttcaactca gtaccatact caccaaggct tagtatgtct tcacccactc     4860

tcccttctct tgcattcctc aaacatgctg agtttattcc agccttaagc ctttgatcta     4920

cgcatcagaa atgttgggcc ccacttcaga tcttctctgc cctgccttct actccagtca     4980

ctgctgtggt aactaattcc atgaagtctt tgaccaggtt ctcagagaat atgatagtac     5040

ctctctttgg attctagctg tatacctttc acttcagcct ccctgacgtg gaatgtctgc     5100

agaacttgtt tggtactccc aattgcacag cccaaaggtg caggggagtt aggtgcccat     5160

ggggccatcc ttgacctagg tggaaagttg ctagtggata actgattact cttttcatca     5220

cctgggcaga cagttctgaa atgcatttcg taagtctcct caaaagagga ggagacttct     5280

gtggcgggtt tggcaataac catccttata ttggctttcc tcttttgttt cactcctgtg     5340

catctctctt gcatcctggg atcgcttctc aaataaatga ctttcattca a              5391


<210>  1967
<211>  3144
<212>  DNA
<213>  homo sapiens

<400>  1967
attctttctt cgtgttcctg tgcgggattg gtgtgcccag gggtttggct ttccaattgg       60

ctaacgccgg ggtgggtggg gaatgtgggg agatttgaat ttgaaaccgg tagggagtga      120

taatccgcat tcagttgtcg aggagtgcca gtcaccttca gtttctggag ctggccgtca      180

acatgtcctt tcctaaggcg cccttgaaac gattcaatga cccttctggt tgtgcaccat      240

ctccaggtgc ttatgatgtt aaaactttag aagtattgaa aggaccagta tcctttcaga      300

aatcacaaag atttaaacaa caaaaagaat ctaaacaaaa tcttaatgtt gacaaagata      360

ctaccttgcc tgcttcagct agaaaagtta agtcttcgga atcaaagaag gaatctcaaa      420

agaatgataa agatttgaag atattagaga aagagattcg tgttcttcta caggaacgtg      480

gtgcccagga caggcggatc caggatctgg aaactgagtt ggaaaagatg gaagcaaggc      540

taaatgctgc actaagggaa aaaacatctc tctctgcaaa taatgctaca ctggaaaaac      600

aacttattga attgaccagg actaatgaac tactaaaatc taagttttct gaaaatggta      660

accagaagaa tttgagaatt ctaagcttgg agttgatgaa acttagaaac aaaagagaaa      720

caaagatgag gggtatgatg gctaagcaag aaggcatgga gatgaagctg caggtcaccc      780

aaaggagtct cgaagagtct caagggaaaa tagcccaact ggagggaaaa cttgtttcaa      840

tagagaaaga aaagattgat gaaaaatctg aaacagaaaa actcttggaa tacatcgaag      900

aaattagttg tgcttcagat caagtggaaa aatacaagct agatattgcc cagttagaag      960

aaaatttgaa agagaagaat gatgaaattt taagccttaa gcagtctctt gaggagaata     1020

ttgttatatt atctaaacaa gtagaagatc taaatgtgaa atgtcagctg cttgaaaaag     1080

aaaaagaaga ccatgtcaac aggaatagag aacacaacga aaatctaaat gcagagatgc     1140

aaaacttaaa acagaagttt attcttgaac aacaggaacg tgaaaagctt caacaaaaag     1200

aattacaaat tgattcactt ctgcaacaag agaaagaatt atcttcgagt cttcatcaga     1260

agctctgttc ttttcaagag gaaatggtta aagagaagaa tctgtttgag gaagaattaa     1320

agcaaacact ggatgagctt gataaattac agcaaaagga ggaacaagct gaaaggctgg     1380

tcaagcaatt ggaagaggaa gcaaaatcta gagctgaaga attaaaactc ctagaagaaa     1440

agctgaaagg gaaggaggct gaactggaga aaagtagtgc tgctcatacc caggccaccc     1500

tgcttttgca ggaaaagtat gacagtatgg tgcaaagcct tgaagatgtt actgctcaat     1560

ttgaaagcta taaagcgtta acagccagtg agatagaaga tcttaagctg gagaactcat     1620

cattacagga aaaagcggcc aaggctggga aaaatgcaga ggatgttcag catcagattt     1680

tggcaactga gagctcaaat caagaatatg taaggatgct tctagatctg cagaccaagt     1740

cagcactaaa ggaaacagaa attaaagaaa tcacagtttc ttttcttcaa aaaataactg     1800

atttgcagaa ccaactcaag caacaggagg aagactttag aaaacagctg gaagatgaag     1860

aaggaagaaa agctgaaaaa gaaaatacaa cagcagaatt aactgaagaa attaacaagt     1920

ggcgtctcct ctatgaagaa ctatataata aaacaaaacc ttttcagcta caactagatg     1980

cttttgaagt agaaaaacag gcattgttga atgaacatgg tgcagctcag gaacagctaa     2040

ataaaataag agattcatat gctaaattat tgggtcatca gaatttgaaa caaaaaatca     2100

agcatgttgt gaagttgaaa gatgaaaata gccaactcaa atcggaagta tcaaaactcc     2160

gctgtcagct tgctaaaaaa aaacaaagtg agacaaaact tcaagaggaa ttgaataaag     2220

ttctaggtat caaacacttt gatccttcaa aggcttttca tcatgaaagt aaagaaaatt     2280

ttgccctgaa gaccccatta aaagaaggca atacaaactg ttaccgagct cctatggagt     2340

gtcaagaatc atggaagtaa acatctgaga aacctgttga agattatttc attcgtcttg     2400

ttgttattga tgttgctgtt attatatttg acatgggtat tttataatgt tgtatttaat     2460

tttaactgcc aatccttaaa tatgtgaaag gaacattttt taccaaagtg tcttttgaca     2520

ttttattttt tcttgcaaat acctcctccc taatgctcac ctttatcacc tcattctgaa     2580

ccctttcgct ggctttccag cttagaatgc atctcatcaa cttaaaagtc agtatcatat     2640

tattatcctc ctgttctgaa accttagttt caagagtcta aaccccagat tcttcagctt     2700

gatcctggag gtcttttcta gtctgagctt ctttagctag gctaaaacac cttggcttgt     2760

tattgcctct actttgattc tgataatgct cacttggtcc tacctattat ccttctactt     2820

gtccagttca aataagaaat aaggacaagc ctaacttcat agaaacctct ctatttttaa     2880

tcagttgttt aataatttac aggttcttag gctccatcct gtttgtatga aattataatc     2940

tgtggattgg cctttaagcc tgcattctta acaaactctt cagttaattc ttagatacac     3000

taaaaatctg agaaactcta catgtaacta tttcttcaga gtttgtcata tactgcttgt     3060

catctgcatg tctactcagc atttgattaa catttgtgta atatgaaata aaattacaca     3120

gtaagtcatt taaccaatta aaaa                                            3144


<210>  1968
<211>  2917
<212>  DNA
<213>  homo sapiens

<400>  1968
attctttctt cgtgttcctg tgcgggattg gtgtgcccag gggtttggct ttccaattgg       60

ctaacgccgg ggtgggtggg gaatgtgggg agatttgaat ttgaaaccgg tagggagtga      120

taatccgcat tcagttgtcg aggagtgcca gtcaccttca gtttctggag ctggccgtca      180

acatgtcctt tcctaaggcg cccttgaaac gattcaatga cccttctgat tcgtgttctt      240

ctacaggaac gtggtgccca ggacaggcgg atccaggatc tggaaactga gttggaaaag      300

atggaagcaa ggctaaatgc tgcactaagg gaaaaaacat ctctctctgc aaataatgct      360

acactggaaa aacaacttat tgaattgacc aggactaatg aactactaaa atctaagttt      420

tctgaaaatg gtaaccagaa gaatttgaga attctaagct tggagttgat gaaacttaga      480

aacaaaagag aaacaaagat gaggggtatg atggctaagc aagaaggcat ggagatgaag      540

ctgcaggtca cccaaaggag tctcgaagag tctcaaggga aaatagccca actggaggga      600

aaacttgttt caatagagaa agaaaagatt gatgaaaaat ctgaaacaga aaaactcttg      660

gaatacatcg aagaaattag ttgtgcttca gatcaagtgg aaaaatacaa gctagatatt      720

gcccagttag aagaaaattt gaaagagaag aatgatgaaa ttttaagcct taagcagtct      780

cttgaggaga atattgttat attatctaaa caagtagaag atctaaatgt gaaatgtcag      840

ctgcttgaaa aagaaaaaga agaccatgtc aacaggaata gagaacacaa cgaaaatcta      900

aatgcagaga tgcaaaactt aaaacagaag tttattcttg aacaacagga acgtgaaaag      960

cttcaacaaa aagaattaca aattgattca cttctgcaac aagagaaaga attatcttcg     1020

agtcttcatc agaagctctg ttcttttcaa gaggaaatgg ttaaagagaa gaatctgttt     1080

gaggaagaat taaagcaaac actggatgag cttgataaat tacagcaaaa ggaggaacaa     1140

gctgaaaggc tggtcaagca attggaagag gaagcaaaat ctagagctga agaattaaaa     1200

ctcctagaag aaaagctgaa agggaaggag gctgaactgg agaaaagtag tgctgctcat     1260

acccaggcca ccctgctttt gcaggaaaag tatgacagta tggtgcaaag ccttgaagat     1320

gttactgctc aatttgaaag ctataaagcg ttaacagcca gtgagataga agatcttaag     1380

ctggagaact catcattaca ggaaaaagcg gccaaggctg ggaaaaatgc agaggatgtt     1440

cagcatcaga ttttggcaac tgagagctca aatcaagaat atgtaaggat gcttctagat     1500

ctgcagacca agtcagcact aaaggaaaca gaaattaaag aaatcacagt ttcttttctt     1560

caaaaaataa ctgatttgca gaaccaactc aagcaacagg aggaagactt tagaaaacag     1620

ctggaagatg aagaaggaag aaaagctgaa aaagaaaata caacagcaga attaactgaa     1680

gaaattaaca agtggcgtct cctctatgaa gaactatata ataaaacaaa accttttcag     1740

ctacaactag atgcttttga agtagaaaaa caggcattgt tgaatgaaca tggtgcagct     1800

caggaacagc taaataaaat aagagattca tatgctaaat tattgggtca tcagaatttg     1860

aaacaaaaaa tcaagcatgt tgtgaagttg aaagatgaaa atagccaact caaatcggaa     1920

gtatcaaaac tccgctgtca gcttgctaaa aaaaaacaaa gtgagacaaa acttcaagag     1980

gaattgaata aagttctagg tatcaaacac tttgatcctt caaaggcttt tcatcatgaa     2040

agtaaagaaa attttgccct gaagacccca ttaaaagaag gcaatacaaa ctgttaccga     2100

gctcctatgg agtgtcaaga atcatggaag taaacatctg agaaacctgt tgaagattat     2160

ttcattcgtc ttgttgttat tgatgttgct gttattatat ttgacatggg tattttataa     2220

tgttgtattt aattttaact gccaatcctt aaatatgtga aaggaacatt ttttaccaaa     2280

gtgtcttttg acattttatt ttttcttgca aatacctcct ccctaatgct cacctttatc     2340

acctcattct gaaccctttc gctggctttc cagcttagaa tgcatctcat caacttaaaa     2400

gtcagtatca tattattatc ctcctgttct gaaaccttag tttcaagagt ctaaacccca     2460

gattcttcag cttgatcctg gaggtctttt ctagtctgag cttctttagc taggctaaaa     2520

caccttggct tgttattgcc tctactttga ttctgataat gctcacttgg tcctacctat     2580

tatccttcta cttgtccagt tcaaataaga aataaggaca agcctaactt catagaaacc     2640

tctctatttt taatcagttg tttaataatt tacaggttct taggctccat cctgtttgta     2700

tgaaattata atctgtggat tggcctttaa gcctgcattc ttaacaaact cttcagttaa     2760

ttcttagata cactaaaaat ctgagaaact ctacatgtaa ctatttcttc agagtttgtc     2820

atatactgct tgtcatctgc atgtctactc agcatttgat taacatttgt gtaatatgaa     2880

ataaaattac acagtaagtc atttaaccaa ttaaaaa                              2917


<210>  1969
<211>  3141
<212>  DNA
<213>  homo sapiens

<400>  1969
attctttctt cgtgttcctg tgcgggattg gtgtgcccag gggtttggct ttccaattgg       60

ctaacgccgg ggtgggtggg gaatgtgggg agatttgaat ttgaaaccgg tagggagtga      120

taatccgcat tcagttgtcg aggagtgcca gtcaccttca gtttctggag ctggccgtca      180

acatgtcctt tcctaaggcg cccttgaaac gattcaatga cccttctggt tgtgcaccat      240

ctccaggtgc ttatgatgtt aaaactttag aagtattgaa aggaccagta tcctttcaga      300

aatcacaaag atttaaacaa caaaaagaat ctaaacaaaa tcttaatgtt gacaaagata      360

ctaccttgcc tgcttcagct agaaaagtta agtcttcgga atcaaaggaa tctcaaaaga      420

atgataaaga tttgaagata ttagagaaag agattcgtgt tcttctacag gaacgtggtg      480

cccaggacag gcggatccag gatctggaaa ctgagttgga aaagatggaa gcaaggctaa      540

atgctgcact aagggaaaaa acatctctct ctgcaaataa tgctacactg gaaaaacaac      600

ttattgaatt gaccaggact aatgaactac taaaatctaa gttttctgaa aatggtaacc      660

agaagaattt gagaattcta agcttggagt tgatgaaact tagaaacaaa agagaaacaa      720

agatgagggg tatgatggct aagcaagaag gcatggagat gaagctgcag gtcacccaaa      780

ggagtctcga agagtctcaa gggaaaatag cccaactgga gggaaaactt gtttcaatag      840

agaaagaaaa gattgatgaa aaatctgaaa cagaaaaact cttggaatac atcgaagaaa      900

ttagttgtgc ttcagatcaa gtggaaaaat acaagctaga tattgcccag ttagaagaaa      960

atttgaaaga gaagaatgat gaaattttaa gccttaagca gtctcttgag gagaatattg     1020

ttatattatc taaacaagta gaagatctaa atgtgaaatg tcagctgctt gaaaaagaaa     1080

aagaagacca tgtcaacagg aatagagaac acaacgaaaa tctaaatgca gagatgcaaa     1140

acttaaaaca gaagtttatt cttgaacaac aggaacgtga aaagcttcaa caaaaagaat     1200

tacaaattga ttcacttctg caacaagaga aagaattatc ttcgagtctt catcagaagc     1260

tctgttcttt tcaagaggaa atggttaaag agaagaatct gtttgaggaa gaattaaagc     1320

aaacactgga tgagcttgat aaattacagc aaaaggagga acaagctgaa aggctggtca     1380

agcaattgga agaggaagca aaatctagag ctgaagaatt aaaactccta gaagaaaagc     1440

tgaaagggaa ggaggctgaa ctggagaaaa gtagtgctgc tcatacccag gccaccctgc     1500

ttttgcagga aaagtatgac agtatggtgc aaagccttga agatgttact gctcaatttg     1560

aaagctataa agcgttaaca gccagtgaga tagaagatct taagctggag aactcatcat     1620

tacaggaaaa agcggccaag gctgggaaaa atgcagagga tgttcagcat cagattttgg     1680

caactgagag ctcaaatcaa gaatatgtaa ggatgcttct agatctgcag accaagtcag     1740

cactaaagga aacagaaatt aaagaaatca cagtttcttt tcttcaaaaa ataactgatt     1800

tgcagaacca actcaagcaa caggaggaag actttagaaa acagctggaa gatgaagaag     1860

gaagaaaagc tgaaaaagaa aatacaacag cagaattaac tgaagaaatt aacaagtggc     1920

gtctcctcta tgaagaacta tataataaaa caaaaccttt tcagctacaa ctagatgctt     1980

ttgaagtaga aaaacaggca ttgttgaatg aacatggtgc agctcaggaa cagctaaata     2040

aaataagaga ttcatatgct aaattattgg gtcatcagaa tttgaaacaa aaaatcaagc     2100

atgttgtgaa gttgaaagat gaaaatagcc aactcaaatc ggaagtatca aaactccgct     2160

gtcagcttgc taaaaaaaaa caaagtgaga caaaacttca agaggaattg aataaagttc     2220

taggtatcaa acactttgat ccttcaaagg cttttcatca tgaaagtaaa gaaaattttg     2280

ccctgaagac cccattaaaa gaaggcaata caaactgtta ccgagctcct atggagtgtc     2340

aagaatcatg gaagtaaaca tctgagaaac ctgttgaaga ttatttcatt cgtcttgttg     2400

ttattgatgt tgctgttatt atatttgaca tgggtatttt ataatgttgt atttaatttt     2460

aactgccaat ccttaaatat gtgaaaggaa cattttttac caaagtgtct tttgacattt     2520

tattttttct tgcaaatacc tcctccctaa tgctcacctt tatcacctca ttctgaaccc     2580

tttcgctggc tttccagctt agaatgcatc tcatcaactt aaaagtcagt atcatattat     2640

tatcctcctg ttctgaaacc ttagtttcaa gagtctaaac cccagattct tcagcttgat     2700

cctggaggtc ttttctagtc tgagcttctt tagctaggct aaaacacctt ggcttgttat     2760

tgcctctact ttgattctga taatgctcac ttggtcctac ctattatcct tctacttgtc     2820

cagttcaaat aagaaataag gacaagccta acttcataga aacctctcta tttttaatca     2880

gttgtttaat aatttacagg ttcttaggct ccatcctgtt tgtatgaaat tataatctgt     2940

ggattggcct ttaagcctgc attcttaaca aactcttcag ttaattctta gatacactaa     3000

aaatctgaga aactctacat gtaactattt cttcagagtt tgtcatatac tgcttgtcat     3060

ctgcatgtct actcagcatt tgattaacat ttgtgtaata tgaaataaaa ttacacagta     3120

agtcatttaa ccaattaaaa a                                               3141


<210>  1970
<211>  6010
<212>  DNA
<213>  homo sapiens

<400>  1970
ctctcttcct cccttcctag agagggaaca acattcatgt gacgggcccc tctgcttctc       60

ccccgcccca tcatctccag cgcgtggtgg gggaactgct ggggaaggcg attggcatcg      120

atctctccat cccttccgag gcccgacttc ggaattgtct tagaagaaag aaggcaagcc      180

accattttac ccacgtaaat atatgaatat atttctgaca ttgaggtgtt ccagaagatg      240

ataaagaaat gatagcagct ccagaaatac caactgattt taatctacta caggagtcag      300

aaacacattt ttcttctgac acagattttg aagatatcga aggaaaaaac caaaagcaag      360

gcaaaggcaa aacttgtaaa aaaggcaaaa agggcccagc agaaaagggc aaaggtggaa      420

atggaggagg aaaacctcct tctggtccaa accgaatgaa tggtcatcac caacagaatg      480

gagtggaaaa catgatgttg tttgaagttg ttaaaatggg caagagtgct atgcagtcgg      540

tggtagatga ttggatagaa tcatacaagc atgaccgaga tatagcactt cttgacctta      600

tcaacttttt tattcagtgt tcaggctgta aaggagttgt cacagcagaa atgtttagac      660

atatgcagaa ctctgagata attcgaaaaa tgactgaaga attcgatgag gatagtggag      720

attatccact taccatggct ggtcctcagt ggaagaagtt caaatccagt ttttgtgaat      780

tcattggcgt gttagtacgg caatgtcaat atagtatcat atatgatgag tatatgatgg      840

atacagtcat ttcacttctt acaggattgt ctgactcaca agtcagagca tttcgacata      900

caagcaccct ggcagctatg aagttgatga cagctttggt gaatgtggca ctaaatctta      960

gcattaatat ggataataca caaagacaat atgaagcaga acggaataaa atgattggaa     1020

aacgagccaa tgagaggcta gaactcctgc tacaaaagcg gaaagagctt caggaaaatc     1080

aagatgaaat agaaaatatg atgaatgcaa tatttaaagg agtgtttgta catagatacc     1140

gtgatgcgat agctgaaatt cgagctattt gcattgaaga gattggcatt tggatgaaga     1200

tgtatagtga tgcctttctt aatgacagtt atttaaaata tgttggttgg actatgcatg     1260

ataagcaagg tgaagtaaga ctcaaatgtc ttactgctct acaagggctt tattataaca     1320

aagagcttaa ttccaaactg gaacttttta ccagtcggtt caaggataga attgtgtcta     1380

tgacccttga caaagaatat gatgttgcag tacaagcaat aaaattactc actcttgttt     1440

tacagagtag tgaagaagtt ctcactgcag aagattgtga aaatgtctat catctggttt     1500

attcagctca ccggccagta gcagtagcag ctggagaatt tctctacaaa aagctcttca     1560

gtcgtagaga tccagaggag gatggaatga tgaaaagaag aggaagacaa ggtccaaatg     1620

ccaaccttgt taagacattg gtttttttct ttctagaaag tgagttacat gagcatgcag     1680

cataccttgt ggatagcatg tgggactgtg ctactgagct gctgaaagac tgggaatgta     1740

tgaatagctt gttactggaa gagccactta gtggagagga agcactaaca gataggcaag     1800

agagtgctct gattgaaata atgctttgta ccattagaca agcggctgaa tgtcatcctc     1860

ccgtgggaag agggacagga aaaagggtgc ttacagcaaa ggagaagaag acacagttgg     1920

atgataggac aaaaatcact gagctttttg ccgtggccct tcctcagtta ttagcaaaat     1980

actctgtaga tgcagaaaag gtgactaact tgttgcagtt gcctcagtac tttgatttgg     2040

aaatatatac cactggacga ttagaaaagc atttggatgc cttattgcga cagatccgga     2100

atattgtaga gaagcacaca gatacagatg ttttggaagc atgttctaaa acttaccatg     2160

cactctgtaa tgaagagttc acaatcttca acagagtaga tatttcaaga agtcaactga     2220

tagatgaatt ggcagataaa tttaaccggc ttcttgaaga ttttctgcaa gagggtgaag     2280

aacctgatga agatgatgca tatcaggtat tgtcaacatt gaagaggatc actgcttttc     2340

ataatgccca tgacctttca aagtgggatt tatttgcttg taattacaaa ctcttgaaaa     2400

ctggaatcga aaatggagac atgcctgagc agattgttat tcacgcactg cagtgtactc     2460

actatgtaat cctttggcaa cttgctaaga taactgaaag cagctctaca aaggaggact     2520

tgctgcgttt aaagaaacaa atgagagtat tttgtcagat atgtcaacat tacctgacca     2580

acgtgaatac tactgttaag gaacaggcct tcactattct gtgtgatatt ttgatgatct     2640

tcagccatca gattatgtca ggagggcgtg acatgttaga gccattagtg tatacccctg     2700

attcttcatt gcagtctgag ttgctcagct ttattttgga tcatgtcttc attgaacagg     2760

atgatgataa taatagtgca gatggtcagc aagaggatga agccagtaaa attgaagctc     2820

tgcacaagag aagaaattta cttgcagcat tttgtaagct aattgtatat actgtggtgg     2880

agatgaatac agctgcagat atcttcaaac agtatatgaa gtattataat gactatggag     2940

atatcatcaa agaaacaatg agtaaaacaa ggcagataga caaaattcag tgtgctaaga     3000

cccttattct cagtctgcaa cagcttttta atgaaatgat acaagaaaat ggctataatt     3060

ttgatagatc atcctctaca tttagtggca taaaagaact tgctcgacgt tttgctttaa     3120

cttttggact tgatcagttg aaaacaagag aagccattgc catgctacac aaagatggca     3180

tagaatttgc ttttaaagag cctaatccgc aaggggagag ccatccacct ttaaatttgg     3240

catttcttga tattctgagt gaattttctt ctaaactact tcgacaagac aaaagaacag     3300

tgtatgttta cttggaaaag ttcatgacct ttcagatgtc actccgaaga gaggatgtgt     3360

ggcttccact gatgtcttac cgaaattctt tgctagctgg tggtgatgat gacaccatgt     3420

cagtcattag tggaatcagc agccgggggt caacagtacg gagtaaaaaa tcaaaaccat     3480

ctacaggaaa acggaaagtg gttgagggca tgcagctttc actcactgaa gaaagtagta     3540

gtagtgacag tatgtggtta agcagagaac aaacactgca cacccctgtt atgatgcaga     3600

caccacaact cacctccact attatgagag agcccaaaag attacggcct gaggatagct     3660

tcatgagtgt ttatccaatg cagactgaac atcatcaaac acctcttgat tataatcggc     3720

gtggcacaag cctaatggaa gatgatgaag agccaattgt ggaagatgtt atgatgtcct     3780

cagaagggag gattgaggat cttaatgagg gaatggattt tgacaccatg gatatagatt     3840

tgccaccatc aaagaacaga cgagagagaa cagaactgaa gcctgatttc tttgatccag     3900

cttcaattat ggatgaatca gttcttggag tgtcaatgtt ttaataccag tacacaatta     3960

aatctgtggt gaagtcattt tctaagtgga agaggaaatt ttaaagtgtg gtagatacag     4020

tgaaattctg tacagatttt tctctaagga gaatatgaca tgcttatgct taccaagatc     4080

aagtgcattg aggggcagtt ttgtttgcct gaataaacgt aaaggacaag taaacaattt     4140

gatgataagc tacagttttt cttagaaagt aaatatttta tttatgcgct gttagttggc     4200

ttttgaatcg attatttcat gctttttttt aaaaaaaaaa aaaaacaaaa taacaatctg     4260

aagaggcatt tggtacagat atgaattctc ttacatttat ttactggttg tactaaataa     4320

tgatgacctc tgctggattt ctgtttacat ccagaaaaca atgttaagga tgtatttatt     4380

cccctaccct gaagaaagtg taggatagaa ttgtttttag cattctaaat ttaaatgctt     4440

aaaacgtcaa tcaacaaaac tttgttttaa atattgtaat tgtggagaaa agtaaactta     4500

taagcagaac ttttacaatt ttttcatcta aaagtatttt aagatatttt taaaatccaa     4560

gagcttctct atacttttca gaaatatcca gatgcagtga actgccagaa ggtaaccagt     4620

ctcaaacatg cttatcccat tatcaaccct gaaagtttgc ttgtccttta agataaaaat     4680

gtaatgttgt gatattcctt ccagtaatgc cactgtattt tgtctccaaa taaaagaagc     4740

ttattgtagt atgtttgcag aaaaattcta aacaaaaatt atacagctta ttagagtgtg     4800

ggaataggga tctaaatttt aaataaaatt atatatatat ataaattggt gctgatttta     4860

taattgcgca gtttgtttag ttttttctta cttttaaatt ccaacttaaa attatgaggt     4920

ttcagaaata tattgaaagt ttaacaatgt ttaaaaatag aaaagcatga gtgttcatgc     4980

tttaaaatga tttttaaatt tgtattttat attgttttat ctatctgtct ttgcaagcag     5040

tcttcaggtt aaagatactt ctaacaggtt acagtacatt tcctctgtat gtaaattaga     5100

tgggataata gaattcataa cccataatat tctttgaaag ctaagcttta aacttcattt     5160

tatgtccttt cacaaataaa ttagtttaaa acagaaagtg gctacttgcc attttgacat     5220

caactcattt tgcgaggctt aggcagctag acatcgttta aaacaaaata ttaacttata     5280

ttacatgtgt atctatctat tgtcagtcgt ctctcagttc ttgaggtata ttattttaat     5340

cattccatgc cttaatatgc ttgcaataca agaatatctt cagatgggtg aataccaaaa     5400

ggctttcagt ttttagtcag aaatcaagca ttgggctgtg gtagccaaaa accataggtt     5460

agctaaaaag atcatgatac aattatttta ttaagtcatg gttaataaca aatgaatcca     5520

gacttgtcta acagattttc catcaacaaa tattgttatg tgcaaaagta ttgcctatgt     5580

tgttttacac accactgcat taactagaac tgctgagagg actgtatata tgattttaaa     5640

cctaagttga ttttttttct cactcttgaa aggagtactt ctttgtgaaa gcagttctta     5700

cagctttgtt ttcaaccagc taaaaatgtt ttatatatta ctctaacctg ttgtcctcca     5760

cattctattg tcctaattgt actgttttct gatttgtatt tatgtcttga gacagtaact     5820

ttttgaataa aaataaacct acagtatgtt gtatgttttc tcttgtactc aaagggggag     5880

ggtggctata aatggtttgc aaatttatat ctattatcac atcttttaat gtgtttgggg     5940

aataatttat agagaatacc atcagtttat atttttaata aatcatatgt atttacaatg     6000

aaaaaaaaaa                                                            6010


<210>  1971
<211>  5632
<212>  DNA
<213>  homo sapiens

<400>  1971
tacttacccc gccagccccg ggaggctcgc agagcgagcg gcgccggcgt catgtgactg       60

cccggagttg gtgccaggag ccagagggga gccaggagcg gagccgcgcg gagccggggc      120

ccgagccgga gcgcagcgag agcgcccgcc gcacgcgcgc ccgtccccgt cccctgcggc      180

cgccaacgcc gcccggactg gagccctgac attgctgcgc tcggggggct ccaggcagcc      240

cgtatcgggg cctttatttc tcgtcggcgg cgccctgcac cgcgcctcgc aaagccaaac      300

accagagcac cctagaaggt ttaactaaaa gaatgctcat gtttgaccca gttcctgtca      360

agcaagaggc catggaccct gtctcagtgt catacccatc taattacatg gaatccatga      420

agcctaacaa gtatggggtc atctactcca caccattgcc tgagaagttc tttcagaccc      480

cagaaggtct gtcgcacgga atacagatgg agccagtgga cctcacggtg aacaagcgga      540

gttcaccccc ttcggctggg aattcgccct cctctctgaa gttcccgtcc tcacaccgga      600

gagcctcgcc tgggttgagc atgccttctt ccagcccacc gataaaaaaa tactcacccc      660

cttctccagg cgtgcagccc ttcggcgtgc cgctgtccat gccaccagtg atggcagctg      720

ccctctcgcg gcatggaata cggagcccgg ggatcctgcc cgtcatccag ccggtggtgg      780

tgcagcccgt cccctttatg tacacaagtc acctccagca gcctctcatg gtctccttat      840

cggaggagat ggaaaattcc agtagtagca tgcaagtacc tgtaattgaa tcatatgaga      900

agcctatatc acagaaaaaa attaaaatag aacctgggat cgaaccacag aggacagatt      960

attatcctga agaaatgtca ccccccttaa tgaactcagt gtcccccccg caagcattgt     1020

tgcaagagaa tcacccttcg gtcatcgtgc agcctgggaa gagaccttta cctgtggaat     1080

ccccggatac tcaaaggaag cggaggatac acagatgtga ttatgatgga tgcaacaaag     1140

tgtacactaa aagctcccac ttgaaagcac acagaagaac acacacagga gaaaaaccct     1200

acaaatgtac atgggaaggg tgcacatgga agtttgctcg gtctgatgaa ctaacaagac     1260

atttccgaaa acatactgga atcaaacctt tccagtgccc ggactgtgac cgcagcttct     1320

cccgttctga ccatcttgcc ctccatagga aacgccacat gctagtctga ttgcctctgt     1380

gtcctgcctc agcgtgactc cccactcacc tggctctctc tctgtcctgc ctcccattat     1440

ctaacacatt ttttacatgt acattttaat ttgattcagc tggtctgaat ctctgaattt     1500

atatcatcca aaacttccat atggtcagta gtagatgttc tctaatcctc cctctcctta     1560

ccacgggtca gacctaaaga atgtgaacac tttttttttt ttttctgggg atgctaagca     1620

aacccttctt acagatacgt ttaatgtaat aagaacaagg gaacatgtaa actaacataa     1680

ccaattgtca gttctccatg tattcctcaa aagaatgtca gagtaaatgt attagaaata     1740

cagtatccag actgctagtc cttgccagag acattcttac ctctgccctg tgataatatt     1800

ttatgcttga cagtgaaaac aagtgtggcc ccttgcaccg gttagctaga agtacagcca     1860

gatttcaagc tagtgcagtc acctcttccg tcattcttca caaatcttgt caacctggat     1920

cttagacttc atctgaatcg agttctttgc cctcctttgt gcctgcagct catatggagg     1980

tctttgccac caatgggaga tgagcccaaa ctttcgatct aggtgggtga tgtgtagcag     2040

ttcaagggaa gggtgctgtg ttttcatagc atggagtcgg aggagagggc catttagcag     2100

ggggagcaga agaggcaatt cctcctgggc taggggttgt cagtgaggtt tcaacatttt     2160

gttagctgtg tgcagcattc ccagagcttc agtctctgtg catactcagc tttgtagaac     2220

catgctgcaa agccatatac cgatggggtt atccatgcaa ctatctccat tcctacaatg     2280

tccttaatat gagatcatca aacattgata gtagggactc catggaatat ttgcccagta     2340

atggtaagaa atctttcggg taagagtatg gatggttctt cttttaccca atctgcttat     2400

agcttttttt gtaaacaggg aaatgttgag tggtacttgt attcccttat caaattaatc     2460

acatagcttt tatacagaaa ctcttcctgt gtgagctgtt aaggtgccaa attggctgtc     2520

atttgtattc atgacacata ccataaagca tctgctaatg ctttaatgga ttgattcaat     2580

taagacctga gtgacactat ttgtaaatat aactagttgt gaagcacaca tacctttatt     2640

ttgggaattt atgagaaaat atagaaaacc acagatcagg gattcatata tgtagctcaa     2700

aaattcccaa aagtttactg ttagagttgg caatttccta tcactatttc agtgtcagaa     2760

caaactgaaa ataatggctc gtgtttatgt tgaagataaa tagcaccatt attgggggaa     2820

gttattcaaa agcaggcttt tgagcaccat agtctaaatg ccaataaaaa taattcatac     2880

atagaaatgt cattggtcct gaatttgaag aaagtgagca acagtagtta aatgtgggtg     2940

catataacca aattcccctt catcaagaat ggaggagaag agagaagaat gaaatcctga     3000

agattcatcc cagccgcaac tcaggatcca acacaacttt aactgggagg aatacattgt     3060

ttgatcattt ttaaaacatc tgtgaatgag tgattccgga ggcctgtgaa ttgtgtgggg     3120

agcttgcttt gatggcactg tgttaataaa agttgtaggg actgtgcacc taagaggcta     3180

agaggtccca ctcatccgcc ctgtgaacca gctgtaaaga aatgtagtta agaaatgcaa     3240

agaaatgtgt tatcttggca cttgggtttg attttccttt ttttaaagca ctgcaaaact     3300

tctttaggat actaaaacat cctaattggg ctgttttttt gttttgtttt gtttttcagc     3360

taaaggcaaa gataattttt ttttcagctg aagtttttct tttttgcaac tatgacatga     3420

attgagtgat aaaatggctc tttgaaaagt agatattgtc tgtattgtaa atgcttagtc     3480

atattcatgg caaagtgttc atttcttgag atggttcttt cacaacacac aagaatcaag     3540

atggaacgca aggaaaatct ttttgttttg accgaggtaa ccagtttatg tgtgttccaa     3600

tccatagaga agtgggggaa agggcgagaa aggatcagat tgatctggga tcagctttga     3660

gcctgagttc agtgaatagc ctcatgggca tctcatggaa ttgatgcatt tgctgtggca     3720

tatttaaatt ttgttcaaaa gatttgaagc aagaccttgc aaagactctt aacattactg     3780

ttcagcttgc ttagattgtg ttaacagttc atttaacaaa gatccgtttt aactctgaac     3840

aaaagcaacc cagagcggcc attctctatt cccatgctgg tcaatacgct ttcattacca     3900

attggccctt accaaacttt tcttatatat atatttgtat tttactatga tagttgagaa     3960

atttagcctc ttagtcattt ttagctgtta ttgtggaaga cctcaaatac aagattagat     4020

gcccttgaac atgttttaat gatgtgtgtc atgttactat caatggtgat ttcaatcgca     4080

atattttaaa ttgatgagaa tgatttgtaa acatgaagtt actattacgt aaattctgtt     4140

tgttatagag tttcttcagt tgttacccaa gtgtcatcct agagaagtca gaagaatcag     4200

aatccatcgt attttagagt tatgtgaatc tacatcataa atgggcatta acattctaaa     4260

ttgcttggtt tggagaatgt gttagcagca tagctatatt caactaggga gatgctaaat     4320

acacagaagt ttcaagagcc ttggaacaga attacagggg aactatatat gtatatgtat     4380

attttattaa acacccatct gcactatcag tattgcacta atgtggaatt tgaaagacta     4440

ttttgctgat actgtatata tgcgcatcat tcctgattag attgttgtaa agacaatctg     4500

aaagatctaa ggttttaaaa taatttggtt tgaaaatata cagttgtctt gaaggaattg     4560

ctgtcataca tgaagttgct ccgagctgtc tttattctct tcttggtcaa ggttaacaat     4620

tgctaaatga tcgcaaattc acctaaacaa tacatttaca aagccatctt tacatgcatt     4680

aaacgagggc tacaacaata ttgttttaca aatactagca cttttttttc tgttatgtac     4740

ttagtgttag agggtcaaaa taatctttct gcttagcatc tcttaaacca tacctgcaaa     4800

tatagcagga ttattacatt tacagtactt taatacttgt ataaactatg cagaaatttt     4860

taataaagtg taatatattt tataagctaa taagactgaa tgggtaaagg tttttagcat     4920

gcattagtat acttgcagat actgaaacat tttggtaatc tttcttacta aagatgtgaa     4980

tgtttaatgt accttctctg tttctactct gtagtccaat gggaattcag taatgacatt     5040

ttgtcatgtc aaactgtgaa cataaatttg tactgtacag tcctcatata ctatatacag     5100

tatgcaatat atattatata cttgttaata aaaccatcag aatattaaat gtgatcatgt     5160

gattacttca tatgcagtga tcactagagc aaaacttaca gagcaatgta agaacccttg     5220

cttagaacat tacttactct gatgggcagt tattgttgat ggagggacag aaaaatagat     5280

ctaactggaa gatgaactac cggaattaac tcagccctca agctatgtcc ctggttttct     5340

gaaaacagcc aacaggaagt ctcctaggct gaaatcataa aactgcagac aatccagcaa     5400

aaatctacaa actcacctag ttcattcttg aaatacttct tgtatttgtt atttatgaac     5460

ccctgcctgc ttccaaaaag aacttgcagc attttgtatt aaaagacgca tgtgtataat     5520

actttaaact tttagagtaa aatatcaaga ctctcatgtt ggggagtggg gaacgaggaa     5580

cagaacaata acgcattaaa gtaaataact ctggaaaaaa aaaaaaaaaa aa             5632


<210>  1972
<211>  1465
<212>  DNA
<213>  homo sapiens

<400>  1972
gagcgacgcc cacggcctgt ctcggccacc agcgtgttcc agcgagcgcc cagccacctc       60

gctcgcagcc tccccagcgc agcagcccgg ctgtgggcct gcggcagccg ggtcttcctg      120

gtccccacct cctggggccg acgggcggca ggaaggggct cggcgggacg cgccatcagg      180

gacctgagga ggaacaacgg aacgcgttcg gaacggcctg gactcccgag actcacccga      240

ctcgtggcca caccgggaga actgaagcgg cagtagccgg cggagacgcc cgacccgaag      300

gccggctgct agggagcaga cagctgaacc gcttgccaga cgccgaaacc cagtgacgcc      360

ctccaccgct ccaccgtgct cccggctcct cgcccccgcc gcccgcgggc cccaaggcgc      420

atgcgccgcc tgtcctggag gggcccattt ccgtccgtcg tggggggagg cacagtgagt      480

ccactggggc acggcagcgt ctaagccaca agccgagcac ataagccagg tcctaacgga      540

gcctatgtgt aagtccacta ctggtgcaag gttgcacact tctaagaaga gcggcgtggg      600

gggctcggcg accttcgctt cagtcgctcc cccgtgcagt cccctgtgcc caagacacag      660

cctgatgctt gtgctccggt gggcggagct tggaggcggc gggaactgca attggtggct      720

ttgaaggcgc ggcgagcggg aacagctctt gaggagtgag actgcaggag atgtgggccg      780

tgccaaagag atggatgaga ctgttgctga gttcatcaag aggaccatct tgaaaatccc      840

catgaatgaa ctgacaacaa tcctgaaggc ctgggatttt ttgtctgaaa atcaactgca      900

gactgtaaat ttccgacaga gaaaggaatc tgtagttcag cacttgatcc atctgtgtga      960

ggaaaagcgt gcaagtatca gtgatgctgc cctgttagac atcatttata tgcaatttca     1020

tcagcaccag aaagtttggg aagtttttca gatgagtaaa ggaccaggtg aagatgttga     1080

cctttttgat atgaaacaat ttaaaaattc gttcaagaaa attcttcaga gagcattaaa     1140

aaatgtgaca gtcagcttca gagaaactga ggagaatgca gtctggattc gaattgcctg     1200

gggaacacag tacacaaagc caaaccagta caaacctacc tacgtggtgt actactccca     1260

gactccgtac gccttcacgt cctcctccat gctgaggcgc aatacaccgc ttctgggtca     1320

ggagttagaa gctactggga aaatctacct ccgacaagag gagatcattt tagatattac     1380

cgaaatgaag aaagcttgca attagtgaac atgaaaggaa aataaaaatt cctcacagtc     1440

atctttttaa aaaaaaaaaa aaaaa                                           1465


<210>  1973
<211>  3643
<212>  DNA
<213>  homo sapiens

<400>  1973
taagaaacga cacacagatt aggcagtgct actcttctta aatctctcat ttgtttccta       60

ggttccctgg ttgtgaaaat acatgagata aatcatgaag gccactatca tcctccttct      120

gcttgcacaa gtttcctggg ctggaccgtt tcaacagaga ggcttatttg actttatgct      180

agaagatgag gcttctggga taggcccaga agttcctgat gaccgcgact tcgagccctc      240

cctaggccca gtgtgcccct tccgctgtca atgccatctt cgagtggtcc agtgttctga      300

tttggaactg ggcaccaatc cgctgaagag ctcaggaatt gaaaatgggg ctttccaggg      360

aatgaagaag ctctcctaca tccgcattgc tgataccaat atcaccagca ttcctcaagg      420

tcttcctcct tcccttacgg aattacatct tgatggcaac aaaatcagca gagttgatgc      480

agctagcctg aaaggactga ataatttggc taagttggga ttgagtttca acagcatctc      540

tgctgttgac aatggctctc tggccaacac gcctcatctg agggagcttc acttggacaa      600

caacaagctt accagagtac ctggtgggct ggcagagcat aagtacatcc aggttgtcta      660

ccttcataac aacaatatct ctgtagttgg atcaagtgac ttctgcccac ctggacacaa      720

caccaaaaag gcttcttatt cgggtgtgag tcttttcagc aacccggtcc agtactggga      780

gatacagcca tccaccttca gatgtgtcta cgtgcgctct gccattcaac tcggaaacta      840

taagtaattc tcaagaaagc cctcattttt ataacctggc aaaatcttgt taatgtcatt      900

gctaaaaaat aaataaaagc tagatactgg aaacctaact gcaatgtgga tgttttaccc      960

acatgactta ttatgcataa agccaaattt ccagtttaag taattgccta caataaaaag     1020

aaattttgcc tgccattttc agaatcatct tttgaagctt tctgttgatg ttaactgagc     1080

tactagagat attcttattt cactaaatgt aaaatttgga gtaaatatat atgtcaatat     1140

ttagtaaagc ttttcttttt taatttccag gaaaaaataa aaagagtatg agtcttctgt     1200

aattcattga gcagttagct catttgagat aaagtcaaat gccaaacact agctctgtat     1260

taatccccat cattactggt aaagcctcat ttgaatgtgt gaattcaata caggctatgt     1320

aaaattttta ctaatgtcat tattttgaaa aaataaattt aaaaatacat tcaaaattac     1380

tattgtatac aagcttaatt gttaatattc cctaaacaca attttatgaa gggagaagac     1440

attggtttgt tgacaataac agtacatctt ttcaagttct cagctatttc ttctacctct     1500

ccctatctta catttgagta tggtaactta tgtcatctat gttgaatgta agcttataaa     1560

gcacaaagca tacatttcct gactggtcta gagaactgat gtttcaattt acccctctgc     1620

taaataaata ttaaaactat catgtgactt catgtaatca ggctgaacat ttctacaatt     1680

actagatgta ttagacgtaa gtattttctt tagttaaacc acccatgtta gaaatgtttt     1740

ctgtagaatt tataaacaac tatcaatgca gacaatttaa taagcctggg gatgatttac     1800

ttacagtaaa catttatcaa attgtacatt tgtgctatca acaattaata agcaaatatg     1860

tgaaaatagt ttctgtcttc tatgaagtta gatatttgat ggttaaaacc cctataaatc     1920

atagtttcat atgggaaaaa ataattgaaa tacagtgtaa atttaaataa tttattaagt     1980

atagcaaata attgaaatat ggtggactaa attttgtcat agaaatatgt gcaagttata     2040

gtagtggctc acatgagagg taatcaattc tgctaatagt agcagaatga gtgcagtgga     2100

acatgaaaaa cttgaggaga taacagttga ggtgggtttc catagatgca taatagttca     2160

agagcaagat ttggtgggga ggcactattc aagacaggga ctaagttcaa aatccaagac     2220

gtatgctggg acacacctct gacaggttgg cataaaggag gcttaatcaa actatttttc     2280

ttcttctgaa acagaagcaa taattttcat ttacatttga catatcccga ggtaatatta     2340

acattaggga aagttactct tttccatctt tccacattct tgcaggacca taaaatctga     2400

attttccagt atttttaata agagggaaga aacctctctt tttcttctct ttttcatctc     2460

ccaagagatc ctcctctcat gactacagtt gaataggtgg tttctattgg aagacattca     2520

ggaattcaag gtgcatgtcc ataaatggac tttttttgtt gttgttcaga gctggacctt     2580

gaatgatgca tccttctctc tgttgtaacc atgaataatg cacccttcat gctatagcct     2640

ttaacgattc acccttctta ttgtaacctt gaatgattca ccctttatgg tgtagccttg     2700

agtgacgcac ccttcatgtt gtagccttca atgatgcaca ctccatgtta tagccttgaa     2760

tgatataccc tttatgctgc agcctttctc ttatggggaa aagcctgcag atatcctgct     2820

gcttaactga caagtgtggt gagaaataag tagaaatcta aagaggggaa gaccattttg     2880

gacacttatc tgcaaggcag atccaacaca cttttccagt agtcaagcta cttctaattt     2940

tgttcagtat caaaatgaga aacaggcctg attctccagc actcttgtca acacaacttc     3000

cccccatatt tatatatata cacacacata tatatcttta tatatataca cacatatata     3060

tctttatata tatatattta tatatatatc tttttgcata tatacatata tatgtatctt     3120

tatttccttt gaaataaaga taaatatagc tgatttcttt ggcttcgaca cttactattt     3180

gcatgactaa gggaagctag ttaacctttc tgtgactcat ttccttgtcc ataaaatggg     3240

aatattaatt gtacatgtct tatggattgg tgtgtgaatt cagttagcga gtgtagaata     3300

taacttatag atcaaagtag agtaaatgga aagggctcaa ctatggtgtt gctactgcca     3360

ttgttattac aggcacacag ttcgagctat aatcatttca agggaaattc ttatgtgtca     3420

gttctggatc gaggtctgag attctgcatt tcaaacaaac ttccaggaat gctgctgctt     3480

cttggtccac acttggagaa ataagtcagc agagagtcct ctcgtttcct attgtaccat     3540

gtctgtcttt tgtctcctgc ttattggcct ctgtaaggaa ctcacagctg ctataataaa     3600

gtaccaaaaa ctgggtggct taaaacaaaa aaaaaaaaaa aaa                       3643


<210>  1974
<211>  3174
<212>  DNA
<213>  homo sapiens

<400>  1974
ctcccgctcg acgcccggct gcggagctgc ctggccatct cctgccctcg gggatgtcgg       60

cgcagtgcac cgcgtgggct cgcgtcccgg cggccctttg cctcggcgcg ccggcgtacg      120

ggaaggtgcg gaccttggat tgagggccga ggatgcccat tgccaagccg ccccggcttt      180

cctaagtgga cgggagggca cggcgacgat tcagcgccgg ctcgcgccgc agctcaaccc      240

aggggagagg ctagtggtaa caggccgagc tggatggatg ggtatgggga gaggggcagg      300

acgttcagcc ctgggattct ggccgaccct cgccttcctt ctctgcagct tccccgcagc      360

cacctccccg tgcaagatcc tcaagtgcaa ctctgagttc tggagcgcca cgtcgggcag      420

ccacgcccca gcctcagacg acacccccga gttctgtgca gccttgcgca gctacgccct      480

gtgcacgcgg cggacggccc gcacctgccg gggtgacctg gcctaccact cggccgtcca      540

tggcatagag gacctcatga gccagcacaa ctgctccaag gatggcccca cctcgcagcc      600

acgcctgcgc acgctcccac cggccggaga cagccaggag cgctcggaca gccccgagat      660

ctgccattac gagaagagct ttcacaagca ctcggccacc cccaactaca cgcactgtgg      720

cctcttcggg gacccacacc tcaggacttt caccgaccgc ttccagacct gcaaggtgca      780

gggcgcctgg ccgctcatcg acaataatta cctgaacgtg caggtcacca acacgcctgt      840

gctgcccggc tcagcggcca ctgccaccag caagctcacc atcatcttca agaacttcca      900

ggagtgtgtg gaccagaagg tgtaccaggc tgagatggac gagctcccgg ccgccttcgt      960

ggatggctct aagaacggtg gggacaagca cggggccaac agcctgaaga tcactgagaa     1020

ggtgtcaggc cagcacgtgg agatccaggc caagtacatc ggcaccacca tcgtggtgcg     1080

ccaggtgggc cgctacctga cctttgccgt ccgcatgcca gaggaagtgg tcaatgctgt     1140

ggaggactgg gacagccagg gtctctacct ctgcctgcgg ggctgccccc tcaaccagca     1200

gatcgacttc caggccttcc acaccaatgc tgagggcacc ggtgcccgca ggctggcagc     1260

cgccagccct gcacccacag cccccgagac cttcccatac gagacagccg tggccaagtg     1320

caaggagaag ctgccggtgg aggacctgta ctaccaggcc tgcgtcttcg acctcctcac     1380

cacgggcgac gtgaacttca cactggccgc ctactacgcg ttggaggatg tcaagatgct     1440

ccactccaac aaagacaaac tgcacctgta tgagaggact cgggacctgc caggcagggc     1500

ggctgcgggg ctgcccctgg ccccccggcc cctcctgggc gccctcgtcc cgctcctggc     1560

cctgctccct gtgttctgct agacgcgtag atgtggaggg aggcgcgggc tccgtcctct     1620

cggcttcccc atgtgtgggc tgggaccgcc cacggggtgc agatctcctg gcgtgtccac     1680

catggccccg cagaacgcca gggaccgcct gctgccaagg gctcaggcac ggacccctcc     1740

ccttctagtg cacgtgacaa ggttgtggtg actggtgcca tgatgtttga cagtagagct     1800

gtgtgagagg gagagcagct cccctcgccc cgcccctgca gtgtgaatgt gtgaaacatc     1860

ccctcaggct gaagcccccc acccccacca gagacacact gggaaccgtc agagtcagct     1920

ccttccccct cgcaatgcac tgaaaggccc ggccgactgc tgctcgccga tccgtggggc     1980

cccctgtgcc cgccacacgc acgcacacac tcttacacga gagcacactc gatcccccta     2040

ggccagcggg gacaccccag ccacacaggg aggcatcctt ggggcttggc cccaggcagg     2100

gcaaccccgg ggcgctgctt ggcaccttag cagactgctg gaaccttttg gccagtaggt     2160

cgtgcccgcc tggtgccttc tggcctgtgg cctccctgcc catgttcacc tggctgctgt     2220

gggtaccagt gcaggtcccg gttttcaggc acctgctcag ctgcccgtct ctggcctggg     2280

cccctgcccc ttccaccctg tgcttagaaa gtcgaagtgc ttggttctaa atgtctaaac     2340

agagaagaga tccttgactt ctgttcctct ctctcctgca gatgcaagag ctcctgggca     2400

ggggtgcctg ggccccaggg tgtggcagga gacccagtgg atggggccag ctggcctgcc     2460

ctgatcctct gcttcctcct cacaacccca agagccccca gcccggtcca tccacgtctg     2520

gagtctgggg agaggagcag ggtcttagga ctctcagctc tgagcatccc tggcagggtc     2580

ttcaacctct aatctcttcc cttaagccct gtggccacac agccaggaga gacttgccgc     2640

tggctcccgc ctcatttcag cccagggtgc tcatccaggg gcccagaaca gtcccacctg     2700

tgctgctgtg cccacagcac aaagccaggc ttcactccca aaagtgcagc caggccctgg     2760

agggtgatcc tgccagcagc cctacagctc cacaccctac ccacccatcg gcagcccctc     2820

tgctgttccc cagggacctc tcatacactg gccaggaggc tgcagaacgt gtgtctcccc     2880

ctccctccaa gaggtcctgc tccctctgcc agaaccgtgt gtgggcgggt gggagggcgc     2940

tcggggcccg gcccctccct ctccctgctg gttttagttg gtccctatgt tggaagtaaa     3000

aagtgaagca ctttattttg gttgtgtttg ctcacgttct gcttggaagt ggggacccct     3060

cactgcgtcc acgtgtctgc gacctgtgtg gagtgtcacc gcgtgtacat actgtaaatt     3120

atttattaat ggctaaatgc aagtaaagtt tggttttttt gttattttct ttta           3174


<210>  1975
<211>  3366
<212>  DNA
<213>  homo sapiens

<400>  1975
gttccattcc cgggggattg gagtagcgtt ggagtcaccg acgccatccc ctcccgcctc       60

tggcgtgcat ggagcatgcg cttccttcct cacttcctct gcaggaggga gcgagagtaa      120

agctacgccc tggcgcgcag tctccgcgtc acaggaactt cagcacccac agggcggaca      180

gcgctcccct ctacctggag acttgactcc cgcgcgcccc aaccctgctt atcccttgac      240

cgtcgagtgt cagagatcct gcagccgccc agtcccggcc cctctcccgc cccacaccca      300

ccctcctggc tcttcctgtt tttactcctc cttttcattc ataacaaaag ctacagctcc      360

aggagcccag cgccgggctg tgacccaagc cgagcgtgga agaatggggt tcctcgggac      420

cggcacttgg attctggtgt tagtgctccc gattcaagct ttccccaaac ctggaggaag      480

ccaagacaaa tctctacata atagagaatt aagtgcagaa agacctttga atgaacagat      540

tgctgaagca gaagaagaca agattaaaaa aacatatcct ccagaaaaca agccaggtca      600

gagcaactat tcttttgttg ataacttgaa cctgctaaag gcaataacag aaaaggaaaa      660

aattgagaaa gaaagacaat ctataagaag ctccccactt gataataagt tgaatgtgga      720

agatgttgat tcaaccaaga atcgaaaact gatcgatgat tatgactcta ctaagagtgg      780

attggatcat aaatttcaag atgatccaga tggtcttcat caactagacg ggactccttt      840

aaccgctgaa gacattgtcc ataaaatcgc tgccaggatt tatgaagaaa atgacagagc      900

cgtgtttgac aagattgttt ctaaactact taatctcggc cttatcacag aaagccaagc      960

acatacactg gaagatgaag tagcagaggt tttacaaaaa ttaatctcaa aggaagccaa     1020

caattatgag gaggatccca ataagcccac aagctggact gagaatcagg ctggaaaaat     1080

accagagaaa gtgactccaa tggcagcaat tcaagatggt cttgctaagg gagaaaacga     1140

tgaaacagta tctaacacat taaccttgac aaatggcttg gaaaggagaa ctaaaaccta     1200

cagtgaagac aactttgagg aactccaata tttcccaaat ttctatgcgc tactgaaaag     1260

tattgattca gaaaaagaag caaaagagaa agaaacactg attactatca tgaaaacact     1320

gattgacttt gtgaagatga tggtgaaata tggaacaata tctccagaag aaggtgtttc     1380

ctaccttgaa aacttggatg aaatgattgc tcttcagacc aaaaacaagc tagaaaaaaa     1440

tgctactgac aatataagca agcttttccc agcaccatca gagaagagtc atgaagaaac     1500

agacagtacc aaggaagaag cagctaagat ggaaaaggaa tatggaagct tgaaggattc     1560

cacaaaagat gataactcca acccaggagg aaagacagat gaacccaaag gaaaaacaga     1620

agcctatttg gaagccatca gaaaaaatat tgaatggttg aagaaacatg acaaaaaggg     1680

aaataaagaa gattatgacc tttcaaagat gagagacttc atcaataaac aagctgatgc     1740

ttatgtggag aaaggcatcc ttgacaagga agaagccgag gccatcaagc gcatttatag     1800

cagcctgtaa aaatggcaaa agatccagga gtctttcaac tgtttcagaa aacataatat     1860

agcttaaaac acttctaatt ctgtgattaa aattttttga cccaagggtt attagaaagt     1920

gctgaattta cagtagttaa ccttttacaa gtggttaaaa catagctttc ttcccgtaaa     1980

aactatctga aagtaaagtt gtatgtaagc tgagattttg tatacagaat ccttatttcc     2040

tcatagactt atattttata atcagaatat gttgctttga aaaagcctct aatggactga     2100

ccttaaaact catccttctt ccactgtctc atccacataa gcactccccg aagaattaag     2160

ggggttctgt tttcaaggca tgccaagtac taaagcacct tgcagagcgt gtctattaca     2220

agatgtcatt tccaccagca gttcccttag gggagctgaa ataaattcac attttctcaa     2280

agtctcatag ctttggagga gccatctgct tttttggctg ctctttttag ctggcttttt     2340

attaggctca gtgacataaa aaggatccag gtaaatgggt ataggatttg ctggatttac     2400

taacaatttc cccctgttct taacacttcc tattagtgac ttttcagaca ttgagtttac     2460

ttataaagag agatatttat gtactctcta agaagacaaa tgaggtcata aacactgcat     2520

aaagcaaggc aaaaatgtat gccacatctc agttatctaa actagattag atccaagcca     2580

agttttctca acagagagca aagggccagg cagtaaggta gaaatagaga taaaaatcat     2640

tccttccttg tgatccaaag ctggtcgagc agctttcctg gaggaaaagg ttaatgaact     2700

tcaggtccct gcaactcagc ccccaccaca aacacagccc tggaaacata cagtggcgca     2760

aggtcctctt gaaatgttaa tggttaatgt tcccaaacca gagaatgctt tgaaaatgta     2820

tcattcagtg taaattaatt acatacatat ttttctatat atttgtttca aactgtaaaa     2880

ataacataat atgtaatttg tgtattagtg agaggtgaag ccagctggac ttcctgggtc     2940

gagtggggcc ttggagaact tttctgtctt acaagaggat tgtaaaatgc acccatcagt     3000

gctctgtaaa acacaccaat cagcgctctg tagctagcaa taggtttgta aaatgcaccc     3060

atcagcactc tgtaaaacgc accaatcagc actctgtaaa atgcaccaat cagcaggatt     3120

ctaaaagtag acaatcacag ggaggattga aaaaaagggc actctgatag ggcaaaaacg     3180

gaacatggga ggggacaaat aagggaataa aatctggcca ccccagccag cagcagcaac     3240

ctgttcaggt cgcctgccgc tgtggaagct ttgtcctttt gctcttcata ataaaccttg     3300

ctactgttca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaa                                                                3366


<210>  1976
<211>  4548
<212>  DNA
<213>  homo sapiens

<400>  1976
cggaagtagc gtcggcgcgg gagctgagcg gagtggcctt gccaccggag gggaagggct       60

gctggcgtta ggcctggctg ggtcgtgcgg ctgagcgtga ggctagaaag aaaaagcgat      120

cctccaagag tgagaacggg agatctgccg aggataacaa cctcccttgt ggccgaaggg      180

cgggggatcc ccacacgagg gctccgcttc gagagacggc gacaaaggaa agttcgtagc      240

gcgttccgga ggcccggcca cctctgagaa gggagacgac gctgctgggt ccgctgagcg      300

gggcgacccg agcttatata gaattggtga taggatcaca acttctgagg tcccagcaag      360

agtcctaaca tctagcagct ctaccaccag gacaggcccc ctaaaactaa ttccaacaag      420

cacctctgaa gtcttctcat tcacaggtta aggctacctt tccagataat ccaacagcta      480

aatcaccagt ttccaagggc atttgcatca cctatggaaa gcatcggatc cttatacacc      540

agatgttctt gacagctcat cccgtcattc ccccctgcac aaaagttgct ataccagcgg      600

acaagcaaga caactactga gcttcttttg attgtcaagt agatataata tcactgccag      660

caaaacagca caaaaagtgt ctcttcacag tatcactacc agttgggact atgctaagta      720

aatcagcttg cctagatgag gaccccttct attcttgggt agccaggatt tgaaggagat      780

actctgacct gtgccagtgg taagtgacta atacttttac acactgaact ggtcctggaa      840

actgagatgt cttctttgta agtgaagaat atacaacata atcttgaaga acggcacagt      900

ggtatgggcc acaagcatac tttatgtgtg taacggactg aaagacaaat taatcttggt      960

gaaaggattt ttcatctctt atttctattt gccagtgtta gtcagtgttc tgctggctta     1020

gattattacc tttttctggt tccttactgt gttttattct gatgggtcct agaaatccct     1080

ctcctgacca cttgtcagaa tcagaaagtg aggaagaaga aaatattagt tacctaaatg     1140

agagttctgg ggaagagtgg gattcctctg aagaagagga ctctatggtg cccaacttat     1200

cgcctcttga gagtcttgcc tggcaggtta agtgcctttt aaaatattcc acaacttgga     1260

aacctttaaa tcctaattcc tggttgtatc atgctaaact gttggatcca agcacaccag     1320

tccatatact tcgagagata ggtctaagac tctcccattg ttcccattgt gtccccaaac     1380

tggaaccaat tcctgaatgg ccccctctgg cctcttgtgg agtcccacct tttcaaaagc     1440

ctcttacaag tcccagccgg ctctctagag atcatgccac tctaaatgga gcactgcaat     1500

ttgccaccaa acagctaagc cgaacattga gtagagccac tcccatacct gaatacctaa     1560

aacagatccc taattcatgt gtttctgggt gttgctgtgg ctggctgact aaaacagtta     1620

aggaaacaac tcgtactgaa cccatcaaca ctacttattc ttacactgac ttccaaaagg     1680

cagttaacaa actcctaact gcatcactgt aaagatctac catttgctct gatatctctg     1740

atgttgctaa ttgagaaagt ggtacaaagt tagtcattac acagcccact aatgccttct     1800

cagtcaaact ctcttatgcc ctggcaagcc aatgaggata ccctttgaca aaccctgtgg     1860

ataaaatgat aatatcaagg tcaggcatgg tggctcacac ctgtaatccc agcactttgg     1920

gaggctgagg cgggtggatc tgctgaagtc agaagtttga gaccagcctt gccaacacag     1980

tgaaaccctg tctctactaa aaataaaaaa attagccggg cgcagcagtg cacgcctgta     2040

atccctgcta ctcgggaggc tgaaacagga gaatcacttg aacccaggag acggaggttg     2100

cggtgagttg agattatgcc actgtactcc agcctgggtg acagagcgag actcagtctc     2160

aaaaaaaaaa aaggagaatt agttaagggg accatattac aaaagatagt tgaatattct     2220

tcacactcac ttctcaccct ccccacccca atttactctg cctttctgaa tggctttaat     2280

gagatacctg attattaatg aagaaaagta gaccaccacc ccttttgtta tccagacttt     2340

agaacagcca ttgttgaaag caagaagtta gctacccaca ataatacctt tctgagcata     2400

ctcttctcta acatacattt ctgtggaagt agttgaatta aattgagtaa ctacacaaag     2460

gaaaatggca gggctatgaa tttctttccc agcttttata tagatgtgcc tacatatgac     2520

actctttagg gttcctttta ttttttcttt tttttttttt ttgaggtagt tgaattaaac     2580

tgggtaacta cacaaaggaa aatggcaggg atatgaattt ctttcccagc ttttatatag     2640

atgtgcctgc atatgacact ctttagagtt cctttcactt tttctttttt ttggaagggg     2700

gcggggaggc aggaggagtg cagttttaag cctagcctat actactacaa acttattatg     2760

gtacttaaaa ttacagcatg aacgttctat atcggagtct cccaccaggc tgtctctgac     2820

taaatcagcc tataagatca tcccttggga ttaaacaaac acctgttctg tagggaatgt     2880

gtttcctgaa tcttggtact cagacttttg tcaagagtaa ataacatttc aaaagatgaa     2940

tggaaaaatg attaagagag catttctgct ttcagcatta actgctaatg gattaaaatt     3000

ttaatctgta tagcatttcc tggagtaaaa gctcaagtac tttccacatc cattgcaaac     3060

ttttcaggaa cccttctaat tttttttttt tttttttttt tgagacggag tcttgctctg     3120

tcgcccaggc tggagtgtag tggcatgatc tcagctcact gcaagctctg cctcccgggt     3180

tcgtgccatt ctcctgccct gcctcccgaa tagctgggac tacaggcgtc caccaccact     3240

cctggctatt tttttgtatt tttagtagag acagggtttc accgtgttag ccaggatggt     3300

cttgatctcc tgacctcgtg atccacctgc ctcggcctcc caaagtgctg ggattgaacc     3360

cttctaattt taaagaacct tgttattaga aaatctcagc ctaatacaat ctgaagttaa     3420

gagttttagc agcattgttt ttctaagtag atttagctat agattttctt ctggccaaac     3480

aaggaagagt atatgccctt gtaaatgagt cttgttttgt ttatttaaat agtcagtcaa     3540

aacgtagaaa tcagtatacg taaaataaaa tgcatgagac tattaaatct tttcatatac     3600

tctacaaata aaatgaaatc tgtgtgtggt cctggttgac tgggcatcta aagggaatca     3660

gaaaagagat tgtgaaaagt tatatatata tcctcttcct tattttagtt ttgctttttc     3720

ctattttcca taattaagtg ccgtttacaa agtggcatca aaaaattgaa gcaggccagg     3780

catggtggct catgcctgta atcccaacag tttgggaggc tgagggcagg tggatcactt     3840

gagatcagga gttcgtgacc agcctggcca acatggtgaa agcccatctc tactaaaaat     3900

ataaaaatta gccgggcgtg gtggcatgtg cctgtaatcg cagctacttg ggaggctaag     3960

acaggagaat tgcttgaacc tgggaggtgg aggttgcaat gagctgagat cgcgccactg     4020

cactccagcc tgggcaacag tgagacaccg tctcaaaaaa aaaaaaggtt aggaatcaca     4080

aattgtgtaa atatatagca actttaagaa gagagaagaa tgcttataac ctagtgaata     4140

tttctgctga gccttagttg tcttgtctaa aggaaaaaag agggaattgt agaataaaag     4200

tatttgttag tggaaattat tgacctgaaa ccatatcata ttgttagtgt aactgaatgt     4260

atcagaaatt gttcctatgt aggtattctg tgaaactggt ttctaaaatg ttacaggaaa     4320

ctgtttcctt tttttttgtt tgtttgttta agtggaggtg ggaggaggta gggaagaggt     4380

ctgaatatta aaatatgttt atgttcatgt gttcataata cgttcctttt tctctctgtg     4440

tgtgtataaa agtgccttgc tcatgaatgc atttttgcta ttcacttcga aaggaagcct     4500

ttccccagct tggcagctga ataaaccaat agctttgtac atgctgaa                  4548


<210>  1977
<211>  3212
<212>  DNA
<213>  homo sapiens

<400>  1977
ggccggctgg aggagctgag gttccgagtg cggccgctgc tgggctggcg ggcgggcaga       60

gcacggcacc ctggcagcag ggcccacgcc acggggccat gggcagctcg agccaggcag      120

gctgctgccc acgcttactg ccagggtgac cccagccctg gggcccagcc acaaccaccc      180

tggcttcatg ccaggggctg ctctggttgc cagtcggcca gcctcggggg tgcagcctgg      240

gctgggactg ctgctggggt gcaggtgagg cagtggccgg gccctcaggc cccagggcag      300

gcaggctgca gggagccaag tcctccatgg cggccccagc cgggaaggcg agcaggacag      360

gggctctgcg gcccagggcc cagaaaggcc gggtgaggcg ggccgtgcgc atctccagcc      420

tcgtggccca ggaggtcctg tccctgggcg ccgacgtgct gcctgagtac aagctgcagg      480

caccgcgcat ccaccgctgg accatcctgc attacagccc cttcaaggcc gtgtgggact      540

ggctcatcct gctgctggtc atctacacgg ctgtcttcac accctactcg gctgccttcc      600

tgctgaagga gacggaagaa ggcccgcctg ctaccgagtg tggctacgcc tgccagccgc      660

tggctgtggt ggacctcatc gtggacatca tgttcattgt ggacatcctc atcaacttcc      720

gcaccaccta cgtcaatgcc aacgaggagg tggtcagcca ccccggccgc atcgccgtcc      780

actacttcaa gggctggttc ctcatcgaca tggtggccgc catccccttc gacctgctca      840

tcttcggctc tggctctgag gagctgatcg ggctgctgaa gactgcgcgg ctgctgcggc      900

tggtgcgcgt ggcgcggaag ctggatcgct actcagagta cggcgcggcc gtgctgttct      960

tgctcatgtg cacctttgcg ctcatcgcgc actggctagc ctgcatctgg tacgccatcg     1020

gcaacatgga gcagccacac atggactcac gcatcggctg gctgcacaac ctgggcgacc     1080

agataggcaa accctacaac agcagcggcc tgggcggccc ctccatcaag gacaagtatg     1140

tgacggcgct ctacttcacc ttcagcagcc tcaccagtgt gggcttcggc aacgtctctc     1200

ccaacaccaa ctcagagaag atcttctcca tctgcgtcat gctcattggc tccctcatgt     1260

atgctagcat cttcggcaac gtgtcggcca tcatccagcg gctgtactcg ggcacagccc     1320

gctaccacac acagatgctg cgggtgcggg agttcatccg cttccaccag atccccaatc     1380

ccctgcgcca gcgcctcgag gagtacttcc agcacgcctg gtcctacacc aacggcatcg     1440

acatgaacgc ggtgctgaag ggcttccctg agtgcctgca ggctgacatc tgcctgcacc     1500

tgaaccgctc actgctgcag cactgcaaac ccttccgagg ggccaccaag ggctgccttc     1560

gggccctggc catgaagttc aagaccacac atgcaccgcc aggggacaca ctggtgcatg     1620

ctggggacct gctcaccgcc ctgtacttca tctcccgggg ctccatcgag atcctgcggg     1680

gcgacgtcgt cgtggccatc ctggggaaga atgacatctt tggggagcct ctgaacctgt     1740

atgcaaggcc tggcaagtcg aacggggatg tgcgggccct cacctactgt gacctacaca     1800

agatccatcg ggacgacctg ctggaggtgc tggacatgta ccctgagttc tccgaccact     1860

tctggtccag cctggagatc accttcaacc tgcgagatac caacatgatc ccgggctccc     1920

ccggcagtac ggagttagag ggtggcttca gtcggcaacg caagcgcaag ttgtccttcc     1980

gcaggcgcac ggacaaggac acggagcagc caggggaggt gtcggccttg gggccgggcc     2040

gggcgggggc agggccgagt agccggggcc ggccgggggg gccgtggggg gagagcccgt     2100

ccagtggccc ctccagccct gagagcagtg aggatgaggg cccaggccgc agctccagcc     2160

ccctccgcct ggtgcccttc tccagcccca ggccccccgg agagccgccg ggtggggagc     2220

ccctgatgga ggactgcgag aagagcagcg acacttgcaa ccccctgtca ggcgccttct     2280

caggagtgtc caacattttc agcttctggg gggacagtcg gggccgccag taccaggagc     2340

tccctcgatg ccccgccccc acccccagcc tcctcaacat ccccctctcc agcccgggtc     2400

ggcggccccg gggcgacgtg gagagcaggc tggatgccct ccagcgccag ctcaacaggc     2460

tggagacccg gctgagtgca gacatggcca ctgtcctgca gctgctacag aggcagatga     2520

cgctggtccc gcccgcctac agtgctgtga ccaccccggg gcctggcccc acttccacat     2580

ccccgctgtt gcccgtcagc cccctcccca ccctcacctt ggactcgctt tctcaggttt     2640

cccagttcat ggcgtgtgag gagctgcccc cgggggcccc agagcttccc caagaaggcc     2700

ccacacgacg cctctcccta ccgggccagc tgggggccct cacctcccag cccctgcaca     2760

gacacggctc ggacccgggc agttagtggg gctgcccagt gtggacacgt ggctcaccca     2820

gggatcaagg cgctgctggg ccgctcccct tggaggccct gctcaggagg ccctgaccgt     2880

ggaaggggag aggaactcga aagcacagct cctcccccag cccttgggac catcttctcc     2940

tgcagtcccc tgggccccag tgagaggggc aggggcaggg ccggcagtag gtggggcctg     3000

tggtcccccc actgccctga gggcattagc tggtctaact gcccggaggc acccggccct     3060

gggccttagg cacctcaagg acttttctgc tatttactgc tcttattgtt aaggataata     3120

attaaggatc atatgaataa ttaatgaaga tgctgatgac tatgaataat aaataattat     3180

cctgaggaga ctccaaaaaa aaaaaaaaaa aa                                   3212


<210>  1978
<211>  2627
<212>  DNA
<213>  homo sapiens

<400>  1978
ggacttcagg cctttttgtg tcctgtttgc taaaggcatg cgggctacag cattcaagag       60

agggagtcgt taacaaaggg aaagagataa atgtaaataa gctcacattt acagaatgag      120

cggtttgcag taaaaagctg cggcagccca gagtctgcta ctttaggctg ggctaacctt      180

tccctgtaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaatg gataaaaata tgcacttcca      240

aagggcgagt tgcccattta catgtttatt agctaattat ctacaggcat cagcacattc      300

tctcatctag cacactcttt cttggggagg aaaatatttc ctaccggtcc atagtgtcag      360

agtggtgaac ccctgcagcc agcaggcctc ctgaaaaaaa agtccatggg tgacagaaga      420

ttcattgact tccaattcca agattcaaat tcaagcctca gacccaggtt gggcaatgct      480

actgccaata atacttgcat tgttgatgat tccttcaagt ataatctcaa tggtgctgtc      540

tacagtgttg tattcatctt gggtctgata accaacagtg tctctctgtt tgtcttctgt      600

ttccgcatga aaatgagaag tgagactgct atttttatca ccaatctagc tgtctctgat      660

ttgctttttg tctgtacact accttttaaa atattttaca acttcaaccg ccactggcct      720

tttggtgaca ccctctgcaa gatctctgga actgcattcc ttaccaacat ctatgggagc      780

atgctctttc tcacctgtat tagtgtggat cgtttcctgg ccattgtcta tccttttcga      840

tctcgtacta ttaggactag gaggaattct gccattgtgt gtgctggtgt ctggatccta      900

gtcctcagtg gcggtatttc agcctctttg ttttccacca ctaatgtcaa caatgcaacc      960

accacctgct ttgaaggctt ctccaaacgt gtctggaaga cttatttatc caagatcaca     1020

atatttattg aagttgttgg gtttatcatt cctctaatat tgaatgtctc ttgctcttct     1080

gtggtgctga gaactcttcg caagcctgct actctgtctc aaattgggac caataagaaa     1140

aaagtactga aaatgatcac agtacatatg gcagtctttg tggtatgctt tgtaccctac     1200

aactctgtcc tcttcttgta tgccctggtg cgctcccaag ctattactaa ttgctttttg     1260

gaaagatttg caaagatcat gtacccaatc accttgtgcc ttgcaactct gaactgttgt     1320

tttgaccctt tcatctatta cttcaccctt gaatcctttc agaagtcctt ctacatcaat     1380

gcccacatca gaatggagtc cctgtttaag actgaaacac ctttgaccac aaagccttcc     1440

cttccagcta ttcaagagga agtgagtgat caaacaacaa ataatggtgg tgaattaatg     1500

ctagaatcca ccttttaggt atgagaaatg tgttcaggtc cagatatggt ttctcctata     1560

atttttccta tgctataaac taaagatttg aagctaatga tactgagaat aatgcaccaa     1620

atccagtcag atacatttgt ttgaaggtat actgtagagt ttttattgct gttttgttca     1680

gtaattatag gtcaaatcta attacaacaa ccaagatgga ttgccaaact cttctgcttg     1740

gttggaattt cattgtatcg cattatccag gtggctagtg gcatttgata atatagagat     1800

gactttgaaa ctttcaaaaa ggtatttcta ttccaatgat atttggtaat taggttgggc     1860

ctataaatat agaacaaatt cagggatttt taaaaaattg tgttactact gatatatgct     1920

agttttattt tatttttttg aactgtcatt gagtttattt tagcacaaga atatttttag     1980

cctaacatta ttaataagaa atgtgtcaaa tttttaacat tggtaaaata tgttatgtgc     2040

attttgaaaa cagaaaacaa attgcgttgg catgtacgtg ggtgggaaga aaaagaaaat     2100

taacaggatt tacacaatta taatcaccag cagtgtgagt ttaaaaaact tcgttgtttt     2160

tacaccaaat taaaattttc atgtcaaact tcaaagccag aaagctgcta aatacgtgtc     2220

tggcaggtaa aagctggaaa attacttaaa acaggaaagt gtcaataaaa aaacttgagc     2280

aacaccaaca tattttttct taaaatgtca cgttatcttc attttgggaa actaggttct     2340

ataaaatatt tatcctccct gttatacttt ggagcacagc acagccagaa aggggctgca     2400

tttgtgccca ggtcaggagc aaattgaaaa aaaaaataaa gtaatacaaa aaaatcaaac     2460

tataaagcaa aaacatttat taaaacctga attaatcctt tttggaggga ggagtagaga     2520

tatataacct gaaaatactt attctttctt atcgaatttt ggagcctaat atagccagga     2580

gctgctgaat ttgtgcccct ggattggaag caaataaaaa aaaaaaa                   2627


<210>  1979
<211>  3088
<212>  DNA
<213>  homo sapiens

<400>  1979
ggggaggggt gtgacgtaca tccggcgagt agctggcggt cccgggtgct gctggttagt       60

gtgctctgag ggagggtccg agccagccgc tgttttgccg gaggagcccc tcaggccggc      120

tgcttccaac cttcaatttg taaaaaaacc agaaaacctc aggatccaca aagtatcatc      180

aaatgaggta gtaagcatta ataatgtctt tcatctttga gtggatctac aatggcttca      240

gcagtgtgct ccagttccta ggactgtaca agaaatctgg aaaacttgta ttcttaggtt      300

tggataatgc aggcaaaacc actcttcttc acatgctcaa agatgacaga ttgggccaac      360

atgttccaac actacatccg acatcagaag agctaacaat tgctggaatg acctttacaa      420

cttttgatct tggtgggcac gagcaagcac gtcgcgtttg gaaaaattat ctcccagcaa      480

ttaatgggat tgtctttctg gtggactgtg cagatcattc tcgcctcgtg gaatccaaag      540

ttgagcttaa tgctttaatg actgatgaaa caatatccaa tgtgccaatc cttatcttgg      600

gtaacaaaat tgacagaaca gatgcaatca gtgaagaaaa actccgtgag atatttgggc      660

tttatggaca gaccacagga aaggggaatg tgaccctgaa ggagctgaat gctcgcccca      720

tggaagtgtt catgtgcagt gtgctcaaga ggcaaggtta cggcgagggt ttccgctggc      780

tctcccagta tattgactga tgtttggacg gtgaaaataa aagagtttta cttctctgga      840

ctgatcctat tcacagcttc ctcatgaact tttctaatag aacaaggaaa gctctccaac      900

catgtctggc gttgagaagc caagagtctc tgtcaactct ctcattgccc agtggtgaca      960

tgtgctcttc tccacactgt tgggaggtaa tgctgcccca cgtgctggtg caggtcagta     1020

tcctgggact tggaagctgg caggatttgc cgggtaaagc tgtatgccat catggggcac     1080

ctgaaaagaa aaacacgtct caccactgtg gttgattcaa aagaaagtga ttctattttt     1140

taaagaaagc gttgttaatg taattggtat ccctcctaac tttttgagtt cacaatttac     1200

ttggtccaga gttttctatt cttttttttt tttaaactaa tgaatgacat ttagatactt     1260

cataaaatta tgaacagata tggaggccag agctcatttg ggtaaactta ctcctgctga     1320

gttagcaggt tggtgagaga agctcccctg agctcacctg tctctctgac tgccttggag     1380

taggtggcat aaccttgtgc acagagaact agaaaagggg cagaaccccg gccttgcagt     1440

tgtggcaggt ttccactgtg gtaagctagg ttcattcctc atcaaggaat gtgtagcaga     1500

ttgttcactg tggaggagtt aattatagaa tgggttattg ttgttattct tactcatgaa     1560

gttacagatt ttagccagtc tttgctttta tacttttgtg aaatttaatt tctctctata     1620

gcaccttcct ttttcgtttt cagttatcaa aagtgacttt gacctcataa aagagttgag     1680

aacatctctc gtgtcacata ctgcaggtgc atcagttact tttgcacaga ttctaggggg     1740

acatttttct gaataggaag acaggacaaa gttaacagct taagggctct taattctgtg     1800

agttgaggac ttaaaagtat tgtagcattt gtttggatcc atgaaaaatg tattcagtgg     1860

gctttaaaat ttccatttgc agaatttggt ctctcaggct gtttgggagc tctttttttt     1920

acattttttc tcctttgaca cctattttat tggtgtttaa agtaaaggtt aacatctgta     1980

gcttttccag gttttttttt tttttttttt ttttttggta tgaaattgtc tttctccatt     2040

gcagaaataa gctagggaaa cactaaccca aaaactttct gtagagctgt tcctttggag     2100

gcagcatcac ttattggcag taaagactca gtataaaagc accggcatcc ctacttgggt     2160

gatggggatt aattttatag cattccattt tcctagtgcc acatgtgaaa ttggattttg     2220

atgatcttaa tctatattct acccttataa taaaagatca aaagatatat ctcctatgaa     2280

cagattggag ataggagatg aaaagttggg aggatgtctt tattctaatg tgagggtagg     2340

gaaaatgtgg ataacattac tggggtgagg gaggcattgt tctttagttg gagttctcat     2400

tcttattctc cagtactgac ttgtggggaa agcatacttt ttcactgcca ggtactgaat     2460

gcagaggctc agtgaagtat atatgtggga agtgcatgca tttcgtttat tagcaaacat     2520

agctggatta agacaaagtt gttggtttgg aaaggggtta aagccttaag tgaacaaatc     2580

tagctaacag tgaatgaact aggtaatata acttgcatat ttttaatttc ctttggttaa     2640

aggtccccca tacttctctg ttcggagaca tgagaagtat gattacttca gtgttagttt     2700

tcttaatttt ttttttcccc tatttgtccc ttgtcacttt gttgcaagct agaaatctgt     2760

gggttataca tagggcagct ctttgtgaaa gtggtttatt ccactggaga aaggggattg     2820

aaaatcagtt agaaccaatg tatttcttgc cccacggaac actattccta taagatagct     2880

gaaagaagct gctgtgagga gctcagctcc aaacacagga tcagcacctt gtataggaat     2940

tcccatgaat tatgacttct cattctgttt tatcagagtg catatatgtc ctacttcagg     3000

aaaagtaaaa cagtcattta cgaaagaaag tcaatctgta tcctaagcat tttaataaaa     3060

agttaaaaca aaaaaaaaaa aaaaaaaa                                        3088


<210>  1980
<211>  7355
<212>  DNA
<213>  homo sapiens

<400>  1980
agtctgcggg cctccggggc agcggcgagg ccggagcgtc gcggcggaga ggacgagacc       60

gggacaagac cagggcagga gggagccggc cagccgcgag aaccccgcac gcccggcaag      120

atgctgtcct ggcggctgca gacgggcccc gagaaggccg agctccagga gctcaacgcc      180

cggctctatg actacgtgtg tcgggtgcgg gagctggagc gcgaaaacct actcctggag      240

gaggagctgc gcggccggcg cgggcgagag ggcctgtggg ccgaggggca ggcccgctgc      300

gccgaggagg cgcgcagctt gcggcagcag ctggacgagc tgagctgggc cactgcgctg      360

gcggagggcg agcgggacgc tctgcggcgc gagctgcggg agctgcagcg cctggatgcg      420

gaggagcgcg ccgcccgcgg ccgcctggac gccgagctgg gtgcgcagca gcgcgagctg      480

caggaggcgc tgggcgcgcg cgccgccctc gaggcgctgc tgggccggct gcaggccgag      540

cgccgaggcc tcgacgcggc ccacgaacgc gacgtgaggg agctgcgcgc gcgcgccgcc      600

agccttacca tgcatttccg cgcccgcgcc accggccccg ccgcgccgcc gccacgcctg      660

cgggaggtgc acgacagcta cgcactgctg gtggccgagt cgtggcggga gacggtgcag      720

ctgtacgagg acgaggtgcg cgagctggag gaggcgctgc ggcgcggcca ggagagcaga      780

ctccaggcgg aggaagagac gcggctgtgc gcgcaggagg cagaggcgct gcggcgcgag      840

gcgctcgggt tggagcagct gcgcgcgcgg ctggaggacg cgctgctgcg gatgcgcgag      900

gagtacggga tacaggccga ggagcggcag agagtgattg actgcctgga ggatgagaag      960

gcaaccctca ccttggccat ggctgactgg ctgcgggact atcaggacct cctgcaggtg     1020

aagaccggcc tcagtctgga ggtggcgacc taccgggcct tattggaagg agaaagtaat     1080

ccagagatag tgatctgggc tgagcacgtt gaaaacatgc cgtcagaatt cagaaacaaa     1140

tcctatcact ataccgactc actactacag agggaaaatg aaaggaatct attttcaagg     1200

cagaaagcac ctttggcaag tttcaatcac agctcggcac tgtattctaa cctgtcaggg     1260

caccgtggat ctcagacggg cacatctatt ggaggtgatg ccagaagagg cttcttgggc     1320

tcgggatatt cttcctcggc cactacccag caggaaaact catacggaaa agccgtcagc     1380

agtcaaacca acgtcagaac tttctctcca acctatggcc ttttaagaaa tactgaggct     1440

caagtgaaaa cattccctga cagaccaaaa gccggagata caagggaggt ccccgtttac     1500

ataggtgaag attccacaat tgcccgcgag tcgtaccggg atcgccgaga caaggtggca     1560

gcaggtgctt cggaaagcac acggtcaaat gagaggaccg tcattctggg aaagaaaaca     1620

gaagtgaaag ccacgaggga gcaagaaaga aacagaccag aaaccatccg aacaaagcca     1680

gaagagaaaa tgttcgattc taaagagaag gcttccgagg agagaaacct aagatgggaa     1740

gaattgacaa agttagataa ggaagcgaga cagagagaaa gccagcagat gaaggagaag     1800

gctaaggaga aggactcacc gaaggagaag agcgtgcgag agagagaggt gccgattagt     1860

ctagaagtat cccaggacag aagagcagag gtgtccccga aaggtttgca gacgcctgtg     1920

aaggatgctg gtggtgggac cggtagagag gcagaagcaa gagagctacg gttcaggttg     1980

ggcaccagtg atgccactgg ttctctgcaa ggcgattcca tgacagaaac cgtagcagaa     2040

aacatcgtta ccagtatcct gaagcagttc actcagtctc cagagacaga agcatctgct     2100

gattcttttc cagacacaaa agtcacttac gtggacagga aagagcttcc tggggaaagg     2160

aaaacaaaga ctgaaatagt tgtggagtct aaactgactg aggatgttga tgtttccgat     2220

gaagctggcc tggactacct tttaagcaag gatattaagg aagtggggct gaaaggcaag     2280

tcagccgagc agatgatagg agacatcatc aacctcggcc tgaaagggag ggaggggaga     2340

gcaaaggtcg tcaacgtgga gatcgtggag gagcccgtga gttatgtcag cggggagaag     2400

ccggaggagt tttccgtccc attcaaagtg gaggaggtcg aagatgtgtc gccaggcccc     2460

tgggggttgg ttaaggagga ggaaggttat ggagaaagcg atgtcacatt ctcagttaat     2520

cagcatcgaa ggaccaagca gcctcaggag aacacgactc acgtggaaga agtgacagag     2580

gcaggtgatt cagagggcga gcagagttat tttgtgtcca ctccagatga acaccccggg     2640

gggcacgaca gagatgacgg ctcggtgtac gggcagatcc acatcgagga ggaatccacc     2700

atcaggtact cttggcagga tgaaatcgtg caggggactc gaaggaggac acagaaggac     2760

ggtgcagtgg gcgagaaggt tgtgaagccc ttggatgtcc cagcgccctc tctggagggg     2820

gacctgggtt ccactcactg gaaagaacaa gctagaagcg gtgaatttca tgccgaaccc     2880

acagtcattg aaaaagaaat taaaataccc cacgaattcc acacctccat gaagggcatc     2940

tcctccaagg agccccggca gcagctggtg gaggtcatcg ggcagctgga ggaaaccctt     3000

cccgagcgca tgagggagga gctgtccgcc ctcaccagag aggggcaggg tgggccgggg     3060

agcgtttccg tggatgtcaa gaaggtccag ggtgctggtg gcagttccgt gaccctggtt     3120

gctgaagtca acgtctcaca aactgtggat gccgatcggt tagacctgga ggagctgagc     3180

aaagatgagg ccagtgagat ggagaaggct gtggagtcgg tggttcggga gagcctgagc     3240

aggcaacgca gcccagcgcc tggcagccca gatgaggaag gtggagcgga ggccccggct     3300

gctggcattc gctttaggcg ttgggccacc cgggagctgt acatcccttc aggcgagagc     3360

gaggttgctg gtggggcctc tcacagctcg ggacagcgca ctccccaggg cccagtgtcg     3420

gccactgtgg aggtcagcag ccccacaggc tttgcccagt cacaggtgct ggaggatgtg     3480

agccaggctg caaggcacat aaaactcggc ccctctgaag tctggaggac tgagcgaatg     3540

tcatatgaag gacccactgc agaagtggtg gaggtaagtg cgggaggtga cctaagtcag     3600

gcagcgagcc cgaccggagc cagccggtct gtgaggcatg tcacgctggg tcccggtcaa     3660

agtccactgt ccagagaagt catcttccta ggccctgccc ctgcctgtcc agaggcatgg     3720

ggctcgccag aacctggccc agcagagtct tctgcagata tggacggatc agggaggcac     3780

agcacatttg gctgcagaca atttcatgct gaaaaggaga ttatttttca gggccccatt     3840

tctgctgcag ggaaggttgg tgattatttt gcaacagaag agtcagtggg tacccagact     3900

tctgtcaggc aactccagtt aggccctaaa gaagggttca gtgggcaaat ccagttcaca     3960

gctccacttt cagacaaggt ggagttgggt gtcataggag attctgtaca catggaaggg     4020

ttgccaggga gcagcacatc catcaggcac atcagcattg ggcctcagag gcatcagacc     4080

acccagcaga tagtttacca tgggctggtt ccccaactgg gggaatctgg tgactcagag     4140

agcactgtgc acggagaggg ctcagcagat gtgcaccagg ccactcacag tcatacctcg     4200

ggtagacaaa ccgttatgac tgaaaagagc accttccaaa gtgtcgtttc tgaatctccc     4260

caggaggata gtgcagagga cacatcaggg gcagaaatga catcgggtgt tagcagatcc     4320

tttaggcaca ttcgactagg tcctacagaa acggaaacct ctgaacacat tgccatccgt     4380

ggacccgtgt ccagaacatt tgtgcttgct ggttcagcgg actcccctga gctaggcaag     4440

ttagcagaca gcagcagaac gctaaggcac attgcaccag ggcccaaaga aacttcgttt     4500

acctttcaga tggatgtgag taacgtagag gcgatccgca gccggacaca ggaagcggga     4560

gctctcggtg tgtctgaccg tggttcctgg agagacgcgg acagtaggaa tgaccaggca     4620

gttggtgtga gctttaaggc ctctgctggg gaaggagacc aggcccacag agaacagggc     4680

aaggagcagg ccatgtttga taagaaggtg cagctccaga gaatggtaga ccaaaggtcg     4740

gtgatttcag atgaaaagaa agttgccctc ctctatctag acaatgagga ggaggagaat     4800

gatgggcatt ggttttaata agcagaaaca ttttgtttta atggcagcct gttggcgacg     4860

tgccaacatc caaaggcctt aacttatttt aagaggccga gggagtctat gaaaatctcc     4920

ccttttttac ttttttaaag agtactcccg gcatggtcaa tttcctttat agttaatccg     4980

taaaggtttc cagttaattc atgccttaaa aggcactgca attttatttt tgagttggga     5040

cttttacaaa acactttttt ccctggagtc ttctctccac ttctggagat gaatttctat     5100

gttttgcacc tggtcacaga catggcttgc atctgtttga aactacaatt aattatagat     5160

gtcaaaacat taaccagatt aaagtaatat atttaagagt aaattttgct tgcatgtgct     5220

aatatgaaat aacagactaa cattttaggg gaaaaataaa tacaatttag actctaaaaa     5280

gtcttttcaa aaagaaatgg gaaataggca gactgtttat gttaaaaaaa ttcttgctaa     5340

atgatttcat ctttaggaaa aaattacttg ccatatagag ctaaattcat cttaagactt     5400

gaatgaattg ctttctatgt acagaacttt aaacaatata gtatttatgg cgaggacagc     5460

tgtagtctgt tgtgatattt cacattctat ttgcacaggt tccctggcac tggtagggta     5520

gatgattatt gggaatcgct tacagtacca tttcattttt tggcactagg tcattaagta     5580

gcacacagtc tgaatgccct tttctggagt ggccagttcc tatcagactg tgcagacttg     5640

cgcttctctg caccttatcc cttagcaccc aaacatttaa tttcactggt gggaggtaga     5700

ccttgaagac aatgaagaga atgccgatac tcagactgca gctggaccgg caagctggct     5760

gtgtacagga aaattggaag cacacagtgg actgtgcctc ttaaagatgc ctttcccaac     5820

cctccattca tgggatgcag gtctttctga gctcaagggt gaaagatgaa tacaataaca     5880

accatgaacc cacctcacgg aagctttttt tgcactttga acagaagtca ttgcagttgg     5940

ggtgttttgt ccagggaaac agtttattaa atagaaggat gttttgggga aggaactgga     6000

tatctctcct gcagcccagc accgagatac ccaggacggg cctggggggc gagaaaggcc     6060

cccatgctca tgggccgcgg agtgtggacc tgtagatagg caccaccgag tttaagatac     6120

tgggatgagc atgcttcatt ggattcattt tattttacac gtcagtattg ttttaaagtt     6180

tctgtctgta aagtgtagca tcatatataa aaagagtttc gctagcagcg catttttttt     6240

agttcaggct agcttctttc acataatgct gtctcagctg tatttccagt aacacagcat     6300

catcgcactg actgtggcgc actggggaat aacagtctga gctagcacca ccctcagcca     6360

ggctacaacg acagcactgg agggtcttcc ctctcagatt cacctggagg ccctcagacc     6420

cccagggtgc acgtctcccc aggtcctggg agtggctacc gcaggtagtt tctggagagc     6480

acgttttctt cattgataag tggaggagaa atgcagcaca gctttcaaga tactatttta     6540

aaaacaccat gaatcagata gggaaagaaa gttgattgga atagcaagtt taaacctttg     6600

ttgtccatct gccaaatgaa ctagtgattg tcagactggt atggaggtga ctgctttgta     6660

aggttttgtc gtttctaata cagacagaga tgtgctgatt ttgttttagc tgtaacaggt     6720

aatggttttt ggatagatga ttgactggtg agaatttggt caaggtgaca gcctcctgtc     6780

tgatgacagg acagactggt ggtgaggagt ctaagtgggc tcagtttgat gtcagtgtct     6840

gggctcatga cttgtaaatg gaagctgatg tgaacaggta attaatatta tgacccactt     6900

ctatttactt tgggaaatat cttggatctt aattatcatc tgcaagtttc aagaagtatt     6960

ctgccaaaag tatttacaag tatggactca tgagctattg ttggttgcta aatgtgaatc     7020

acgcgggagt gagtgtgccc ttcacactgt gacattgtga cattgtgaca agctccatgt     7080

cctttaaaat cagtcactct gcacacaaga gaaatcaact tcgtggttgg atggggccgg     7140

aacacaacca gtctttttgt atttattgtt actgagacaa aacagtactc actgagtgtt     7200

tttcagtttc ctactggtgg ttttgatatt gtttgtttaa gatgtatatt tagaatgaca     7260

tcatctaaga agctgatttt gctaaactcc tgttccctac aatgggaaat gtcacaagaa     7320

tgtgcaaaaa taaaaatctg aggaaaaaac ccaca                                7355


<210>  1981
<211>  1369
<212>  DNA
<213>  homo sapiens

<400>  1981
cacaacattt ccttgtatgt ggatagcgtg aaagaagctt gtgatcctgc ccccaccctc       60

cccaccgcca cattttttaa agtgtattgt tgcagcatct ggcagtgaga ctgaggatga      120

ggacagcatg gacattccct tggacctttc ttcatccgct ggctcaggca agagaaggag      180

aaggggcaac ctacccaagg agtctgtgca gattcttcgg gattggctgt atgagcaccg      240

ttacaatgcc tatccttcag agcaagaaaa agcgttgctg tcccagcaaa cacacctgtc      300

tacgctacag gtctgtaact ggttcatcaa cgcccgccgc aggctcctcc ctgacatgct      360

gagaaaggat ggcaaagatc caaatcagtt cacaatttcc cgccgtgggg ccaagatttc      420

tgaaacgagc tctgtggagt ccgtgatggg catcaaaaac ttcatgccag ctctagagga      480

gaccccattt cattcctgta cagctgggcc aaacccaacc ctagggaggc cactgtctcc      540

taagccgtca tccccgggat cagttttggc tcgtccatca gtgatctgcc ataccactgt      600

gactgcattg aaagatgtcc ctttctctct ctgccagtcg gtcggtgtgg gacaaaacac      660

agatatacag cagatagcgg ccaaaaactt cacagacacc tctctcatgt acccagagga      720

cacttgtaaa tctggaccaa gtacgaatac acagagtggt cttttcaaca ctcctccccc      780

tactccaccg gacctcaacc aggacttcag tggatttcag cttctagtgg atgttgcact      840

caaacgggct gcagagatgg agcttcaggc aaaacttaca gcttaaccca ttttcaagca      900

aaacagttct cagaaatgtc atgattgccg gggtgaaggc aagagatgaa ttgcattatt      960

ttatatattt tttattaata tttgcacatg ggattgctaa aacagcttcc tgttactgag     1020

atgtcttcaa tggaatacag tcattccaag aactataaac ttaaagctac tgtagaaaca     1080

aagggttttc ttttttaaat gtttcttggt agattattca taatgtgaga tggttcccaa     1140

tatcatgtga tttttttttt cctccccttc cctttttttg ttattttttc agactgtgca     1200

atacttagag aacctatagc atcttctcat tcccatgtgg aacaggatgc ccacatactg     1260

tctaattaat aaattttcca ttttttttca aacaagtatg aatctagttg gttgatgcct     1320

tttttttcat gacataataa agtattttct ttaaaaaaaa aaaaaaaaa                 1369


<210>  1982
<211>  2627
<212>  DNA
<213>  homo sapiens

<400>  1982
ggacttcagg cctttttgtg tcctgtttgc taaaggcatg cgggctacag cattcaagag       60

agggagtcgt taacaaaggg aaagagataa atgtaaataa gctcacattt acagaatgag      120

cggtttgcag taaaaagctg cggcagccca gagtctgcta ctttaggctg ggctaacctt      180

tccctgtaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaatg gataaaaata tgcacttcca      240

aagggcgagt tgcccattta catgtttatt agctaattat ctacaggcat cagcacattc      300

tctcatctag cacactcttt cttggggagg aaaatatttc ctaccggtcc atagtgtcag      360

agtggtgaac ccctgcagcc agcaggcctc ctgaaaaaaa agtccatggg tgacagaaga      420

ttcattgact tccaattcca agattcaaat tcaagcctca gacccaggtt gggcaatgct      480

actgccaata atacttgcat tgttgatgat tccttcaagt ataatctcaa tggtgctgtc      540

tacagtgttg tattcatctt gggtctgata accaacagtg tctctctgtt tgtcttctgt      600

ttccgcatga aaatgagaag tgagactgct atttttatca ccaatctagc tgtctctgat      660

ttgctttttg tctgtacact accttttaaa atattttaca acttcaaccg ccactggcct      720

tttggtgaca ccctctgcaa gatctctgga actgcattcc ttaccaacat ctatgggagc      780

atgctctttc tcacctgtat tagtgtggat cgtttcctgg ccattgtcta tccttttcga      840

tctcgtacta ttaggactag gaggaattct gccattgtgt gtgctggtgt ctggatccta      900

gtcctcagtg gcggtatttc agcctctttg ttttccacca ctaatgtcaa caatgcaacc      960

accacctgct ttgaaggctt ctccaaacgt gtctggaaga cttatttatc caagatcaca     1020

atatttattg aagttgttgg gtttatcatt cctctaatat tgaatgtctc ttgctcttct     1080

gtggtgctga gaactcttcg caagcctgct actctgtctc aaattgggac caataagaaa     1140

aaagtactga aaatgatcac agtacatatg gcagtctttg tggtatgctt tgtaccctac     1200

aactctgtcc tcttcttgta tgccctggtg cgctcccaag ctattactaa ttgctttttg     1260

gaaagatttg caaagatcat gtacccaatc accttgtgcc ttgcaactct gaactgttgt     1320

tttgaccctt tcatctatta cttcaccctt gaatcctttc agaagtcctt ctacatcaat     1380

gcccacatca gaatggagtc cctgtttaag actgaaacac ctttgaccac aaagccttcc     1440

cttccagcta ttcaagagga agtgagtgat caaacaacaa ataatggtgg tgaattaatg     1500

ctagaatcca ccttttaggt atgagaaatg tgttcaggtc cagatatggt ttctcctata     1560

atttttccta tgctataaac taaagatttg aagctaatga tactgagaat aatgcaccaa     1620

atccagtcag atacatttgt ttgaaggtat actgtagagt ttttattgct gttttgttca     1680

gtaattatag gtcaaatcta attacaacaa ccaagatgga ttgccaaact cttctgcttg     1740

gttggaattt cattgtatcg cattatccag gtggctagtg gcatttgata atatagagat     1800

gactttgaaa ctttcaaaaa ggtatttcta ttccaatgat atttggtaat taggttgggc     1860

ctataaatat agaacaaatt cagggatttt taaaaaattg tgttactact gatatatgct     1920

agttttattt tatttttttg aactgtcatt gagtttattt tagcacaaga atatttttag     1980

cctaacatta ttaataagaa atgtgtcaaa tttttaacat tggtaaaata tgttatgtgc     2040

attttgaaaa cagaaaacaa attgcgttgg catgtacgtg ggtgggaaga aaaagaaaat     2100

taacaggatt tacacaatta taatcaccag cagtgtgagt ttaaaaaact tcgttgtttt     2160

tacaccaaat taaaattttc atgtcaaact tcaaagccag aaagctgcta aatacgtgtc     2220

tggcaggtaa aagctggaaa attacttaaa acaggaaagt gtcaataaaa aaacttgagc     2280

aacaccaaca tattttttct taaaatgtca cgttatcttc attttgggaa actaggttct     2340

ataaaatatt tatcctccct gttatacttt ggagcacagc acagccagaa aggggctgca     2400

tttgtgccca ggtcaggagc aaattgaaaa aaaaaataaa gtaatacaaa aaaatcaaac     2460

tataaagcaa aaacatttat taaaacctga attaatcctt tttggaggga ggagtagaga     2520

tatataacct gaaaatactt attctttctt atcgaatttt ggagcctaat atagccagga     2580

gctgctgaat ttgtgcccct ggattggaag caaataaaaa aaaaaaa                   2627


<210>  1983
<211>  6021
<212>  DNA
<213>  homo sapiens

<400>  1983
cggcgaacag acgttctttc tcctccatgc agttacacaa aaggagggct acggaaacta       60

aaagtttcgg ggcctctggc tcggtgcgtg gagaaaagag aaaacctgga gacgggatat      120

gaagatcaat gatgcagact gatggttttg atgaagctgg gcatttataa ctagattcat      180

taaggaatac aaagaaaata cttaaaggga tcaataatgg tgtcttctgg ttgcagaatg      240

cgaagtctgt ggtttatcat tgtaatcagc ttcttaccaa atacagaagg tttcagcaga      300

gcagctttac catttgggct ggtgaggcga gaattatcct gtgaaggtta ttctatagat      360

ctgcgatgcc cgggcagtga tgtcatcatg attgagagcg ctaactatgg tcggacggat      420

gacaagattt gtgatgctga cccatttcag atggagaata cagactgcta cctccccgat      480

gccttcaaaa ttatgactca aaggtgcaac aatcgaacac agtgtatagt agttactggg      540

tcagatgtgt ttcctgatcc atgtcctgga acatacaaat accttgaagt ccaatatgaa      600

tgtgtccctt acatttttgt gtgtcctggg accttgaaag caattgtgga ctcaccatgt      660

atatatgaag ctgaacaaaa ggcgggtgct tggtgcaagg accctcttca ggctgcagat      720

aaaatttatt tcatgccctg gactccctat cgtaccgata ctttaataga atatgcttct      780

ttagaagatt tccaaaatag tcgccaaaca acaacatata aacttccaaa tcgagtagat      840

ggtactggat ttgtggtgta tgatggtgct gtcttcttta acaaagaaag aacgaggaat      900

attgtgaaat ttgacttgag gactagaatt aagagtggcg aggccataat taactatgcc      960

aactaccatg atacctcacc atacagatgg ggaggaaaga ctgatatcga cctagcagtt     1020

gatgaaaatg gtttatgggt catttacgcc actgaacaga acaatggaat gatagttatt     1080

agccagctga atccatacac tcttcgattt gaagcaacgt gggagactgt atacgacaaa     1140

cgtgccgcat caaatgcttt tatgatatgc ggagtcctct atgtggttag gtcagtttat     1200

caagacaatg aaagtgaaac aggcaagaac tcaattgatt acatttataa tacccgatta     1260

aaccgaggag aatatgtaga tgttcccttc cccaaccagt atcagtatat tgctgcagtg     1320

gattacaatc caagagataa ccaactttac gtgtggaaca ataacttcat tttacgatat     1380

tctctggagt ttggtccacc tgatcctgcc caagtgccta ccacagctgt gacaataact     1440

tcttcagctg agctgttcaa aaccataata tcaaccacaa gcactacttc acagaaaggc     1500

cccatgagca caactgtagc tggatcacag gaaggaagca aagggacaaa accacctcca     1560

gcagtttcta caaccaaaat tccacctata acaaatattt ttcccctgcc agagagattc     1620

tgtgaagcat tagactccaa ggggataaag tggcctcaga cacaaagggg aatgatggtt     1680

gaacgaccat gccctaaggg aacaagagga actgcctcat atctctgcat gatttccact     1740

ggaacatgga accctaaggg ccccgatctt agcaactgta cctcacactg ggtgaatcag     1800

ctggctcaga agatcagaag cggagaaaat gctgctagtc ttgccaatga actggctaaa     1860

cataccaaag ggccagtgtt tgctggggat gtaagttctt cagtgagatt gatggagcag     1920

ttggtggaca tccttgatgc acagctgcag gaactgaaac ctagtgaaaa agattcagct     1980

ggacggagtt ataacaaggc aattgttgac acagtggaca accttctgag acccgaagct     2040

ttggaatcat ggaaacatat gaattcttct gaacaagcac atactgcaac aatgttactc     2100

gatacattgg aagaaggagc ttttgtccta gctgacaatc ttttagaacc aacaagggtc     2160

tcaatgccca cagaaaatat tgtcctggaa gttgccgtac tcagtacaga aggacagatc     2220

caagacttta aatttcctct gggcatcaaa ggagcaggca gctcaatcca actgtccgca     2280

aataccgtca aacagaacag caggaatggg cttgcaaagt tggtgttcat catttaccgg     2340

agcctgggac agttccttag tacagaaaat gcaaccatta aactgggtgc tgattttatt     2400

ggtcgtaata gcaccattgc agtgaactct cacgtcattt cagtttcaat caataaagag     2460

tccagccgag tatacctgac tgatcctgtg ctttttaccc tgccacacat tgatcctgac     2520

aattatttca atgcaaactg ctccttctgg aactactcag agagaactat gatgggatat     2580

tggtctaccc agggctgcaa gctggttgac actaataaaa ctcgaacaac gtgtgcatgc     2640

agccacctaa ccaattttgc aattctcatg gcccacaggg aaattgcata taaagatggc     2700

gttcatgaat tacttcttac agtcatcacc tgggtgggaa ttgtcatttc ccttgtttgc     2760

ctggctatct gcatcttcac cttctgcttt ttccgtggcc tacagagtga ccgaaatact     2820

attcacaaga acctttgtat caaccttttc attgctgaat ttattttcct aataggcatt     2880

gataagacaa aatatgcgat tgcatgccca atatttgcag gacttctaca ctttttcttt     2940

ttggcagctt ttgcttggat gtgcctagaa ggtgtgcagc tctacctaat gttagttgaa     3000

gtttttgaaa gtgaatattc aaggaaaaaa tattactatg ttgctggtta cttgtttcct     3060

gccacagtgg ttggagtttc agctgctatt gactataaga gctatggaac agaaaaagct     3120

tgctggcttc atgttgataa ctactttata tggagcttca ttggacctgt taccttcatt     3180

attctgctaa atattatctt cttggtgatc acattgtgca aaatggtgaa gcattcaaac     3240

actttgaaac cagattctag caggttggaa aacattaagt cttgggtgct tggcgctttc     3300

gctcttctgt gtcttcttgg cctcacctgg tcctttgggt tgctttttat taatgaggag     3360

actattgtga tggcatatct cttcactata tttaatgctt tccagggagt gttcattttc     3420

atctttcact gtgctctcca aaagaaagta cgaaaagaat atggcaagtg cttcagacac     3480

tcatactgct gtggaggcct cccaactgag agtccccaca gttcagtgaa ggcatcaacc     3540

accagaacca gtgctcgcta ttcctctggc acacagagtc gtataagaag aatgtggaat     3600

gatactgtga gaaaacaatc agaatcttct tttatctcag gtgacatcaa tagcacttca     3660

acacttaatc aaggacattc actgaacaat gccagggata caagtgccat ggatactcta     3720

ccgctaaatg gtaattttaa caacagctac tcgctgcaca agggtgacta taatgacagc     3780

gtgcaagttg tggactgtgg actaagtctg aatgatactg cttttgagaa aatgatcatt     3840

tcagaattag tgcacaacaa cttacggggc agcagcaaga ctcacaacct cgagctcacg     3900

ctaccagtca aacctgtgat tggaggtagc agcagtgaag atgatgctat tgtggcagat     3960

gcttcatctt taatgcacag cgacaaccca gggctggagc tccatcacaa agaactcgag     4020

gcaccactta ttcctcagcg gactcactcc cttctgtacc aaccccagaa gaaagtgaag     4080

tccgagggaa ctgacagcta tgtctcccaa ctgacagcag aggctgaaga tcacctacag     4140

tcccccaaca gagactctct ttatacaagc atgcccaatc ttagagactc tccctatccg     4200

gagagcagcc ctgacatgga agaagacctc tctccctcca ggaggagtga gaatgaggac     4260

atttactata aaagcatgcc aaatcttgga gctggccatc agcttcagat gtgctaccag     4320

atcagcaggg gcaatagtga tggttatata atccccatta acaaagaagg gtgtattcca     4380

gaaggagatg ttagagaagg acaaatgcag ctggttacaa gtctttaatc atacagctaa     4440

ggaattccaa gggccacatg cgagtattaa taaataaaga caccattggc ctgacgcagc     4500

tccctcaaac tctgcttgaa gagatgactc ttgacctgtg gttctctggt gtaaaaaaga     4560

tgactgaacc ttgcagttct gtgaattttt ataaaacata caaaaacttt gtatatacac     4620

agagtatact aaagtgaatt atttgttaca aagaaaagag atgccagcca ggtattttaa     4680

gattctgctg ctgtttagag aaattgtgaa acaagcaaaa caaaactttc cagccatttt     4740

actgcagcag tctgtgaact aaatttgtaa atatggctgc accatttttg taggcctgca     4800

ttgtattata tacaagacgt aggctttaaa atcctgtggg acaaatttac tgtaccttac     4860

tattcctgac aagacttgga aaagcaggag agatattctg catcagtttg cagttcactg     4920

caaatctttt acattaaggc aaagattgaa aacatgctta accactagca atcaagccac     4980

aggccttatt tcatatgttt cctcaactgt acaatgaact attctcatga aaaatggcta     5040

aagaaattat attttgttct attgctaggg taaaataaat acatttgtgt ccaactgaaa     5100

tataattgtc attaaaataa ttttaaagag tgaagaaaat attgtgaaaa gctcttggtt     5160

gcacatgtta tgaaatgttt tttcttacac tttgtcatgg taagttctac tcattttcac     5220

ttcttttcca ctgtatacag tgttctgctt tgacaaagtt agtctttatt acttacattt     5280

aaatttctta ttgccaaaag aacgtgtttt atggggagaa acaaactctt tgaagccagt     5340

tatgtcatgc cttgcacaaa agtgatgaaa tctagaaaag attgtgtgtc acccctgttt     5400

attcttgaac agagggcaaa gagggcactg ggcacttctc acaaactttc tagtgaacaa     5460

aaggtgccta ttctttttta aaaaaataaa ataaaacata aatattactc ttccatattc     5520

cttctgccta tatttagtaa ttaatttatt ttatgataaa gttctaatga aatgtaaatt     5580

gtttcagcaa aattctgctt ttttttcatc cctttgtgta aacctgttaa taatgagccc     5640

atcactaata tccagtgtaa agtttaacac ggtttgacag taaataaatg tgaatttttt     5700

caagtagtta acatgtgaac ttttatgtat gatacataat tggctttaac atgttggtcc     5760

attcccacct tggtttaagt aacgtcatac caaagtccat ggatatatga aaggatacaa     5820

ttaagttgcc tgtttgttct ttatgctgaa aggaatatat gtcttccaat tgcccactac     5880

atatgcacaa aatctgctgg ataagtttta agagggatat attctgaaag catttttgtt     5940

tgttgcattg taccaggact aaaaaaagaa ggattggaag ttctgccatc aaatttgggt     6000

atcataaaaa gtttttaact g                                               6021


<210>  1984
<211>  2264
<212>  DNA
<213>  homo sapiens

<400>  1984
cttttgaagt taacaaaaat tgagtccctg gctgggaggt cccccgagtg ttccgctgtg       60

ggctggaggt ggcgtttctg tcgtgattta tgtggagtgg ttcaaaacag aagttaatca      120

ctcgggaagc ggacgggagg ggcggcgcta ctgcgcatgc ccgggagccg cctggagttt      180

ggaactccac attctttcag acccggcccg ctgcggggcg ttcctggggg gtagcctcaa      240

ggccagcggg gttccttcgg ctgcgtttct gtgggaggcc ctgaaacgcg cggagcttcc      300

ctctgcctcc aggctttccc agcgagagtg aaattaaact tgaaactcgg atcaactggc      360

agtcgttgtt ggtagaacgc cctaaggacc cctccccgcg ggacggaggg aggactcggg      420

acagggaatt ggccctggga gaaaacgcgc ggggggcgtc cgagacgccc cgtgaaagcc      480

gtgccgaccc ttgggaggac tgacaggtct agagacacgc gctgtctgtt gtggtgggcc      540

tcccgggaat aagtgagggg ctctgtgttt cgaggatggt tctagcgcag agccgggtgt      600

ctgccggggt gggctccccg cattgttcgg gctccggcgg gggcggctct gattcctttc      660

catggcccgc ctcccacccc gggaatcccc agtgctcctt ttccacggct tttctggcgt      720

ccccccgact ctcccgcggc actttggcct accttccccc agcgccgtgg tcctccctgg      780

cgaccccctc tgcgctcctg gggtcctcct gcgccccccc tcctccaccg gcgcgctgcc      840

cacagccgcg tgccctctcc ccggagctgg ggaccaaggc tgggccccgc cggccgcatc      900

ggtgggaact tccgcggtcc ccatcccagg gcgcacaggg tccagctcct cggcgccgac      960

tcctggaaac aatgaaaggt attgttgcag catctggcag tgagactgag gatgaggaca     1020

gcatggacat tcccttggac ctttcttcat ccgctggctc aggcaagaga aggagaaggg     1080

gcaacctacc caaggagtct gtgcagattc ttcgggattg gctgtatgag caccgttaca     1140

atgcctatcc ttcagagcaa gaaaaagcgt tgctgtccca gcaaacacac ctgtctacgc     1200

tacaggtctg taactggttc atcaacgccc gccgcaggct cctccctgac atgctgagaa     1260

aggatggcaa agatccaaat cagttcacaa tttcccgccg tggggccaag atttctgaaa     1320

cgagctctgt ggagtccgtg atgggcatca aaaacttcat gccagctcta gaggagaccc     1380

catttcattc ctgtacagct gggccaaacc caaccctagg gaggccactg tctcctaagc     1440

cgtcatcccc gggatcagtt ttggctcgtc catcagtgat ctgccatacc actgtgactg     1500

cattgaaaga tgtccctttc tctctctgcc agtcggtcgg tgtgggacaa aacacagata     1560

tacagcagat agcggccaaa aacttcacag acacctctct catgtaccca gaggacactt     1620

gtaaatctgg accaagtacg aatacacaga gtggtctttt caacactcct ccccctactc     1680

caccggacct caaccaggac ttcagtggat ttcagcttct agtggatgtt gcactcaaac     1740

gggctgcaga gatggagctt caggcaaaac ttacagctta acccattttc aagcaaaaca     1800

gttctcagaa atgtcatgat tgccggggtg aaggcaagag atgaattgca ttattttata     1860

tattttttat taatatttgc acatgggatt gctaaaacag cttcctgtta ctgagatgtc     1920

ttcaatggaa tacagtcatt ccaagaacta taaacttaaa gctactgtag aaacaaaggg     1980

ttttcttttt taaatgtttc ttggtagatt attcataatg tgagatggtt cccaatatca     2040

tgtgattttt tttttcctcc ccttcccttt ttttgttatt ttttcagact gtgcaatact     2100

tagagaacct atagcatctt ctcattccca tgtggaacag gatgcccaca tactgtctaa     2160

ttaataaatt ttccattttt tttcaaacaa gtatgaatct agttggttga tgcctttttt     2220

ttcatgacat aataaagtat tttctttaaa aaaaaaaaaa aaaa                      2264


<210>  1985
<211>  1498
<212>  DNA
<213>  homo sapiens

<400>  1985
gaaactccaa acaagtttga gatcagcgtt ggctgggggg aggcagtggg ggtgcatcta       60

cgggagcggt tgggctgtaa gctttcgcta catcacagaa ttgtgccagt gtttctcttt      120

ggagtgcctc gccagcttta acaaccgttt ggatatgact tgctcgggca aaagttgtgc      180

attggcccga tcaagcctga cttctagcca aggtattgtt gcagcatctg gcagtgagac      240

tgaggatgag gacagcatgg acattccctt ggacctttct tcatccgctg gctcaggcaa      300

gagaaggaga aggggcaacc tacccaagga gtctgtgcag attcttcggg attggctgta      360

tgagcaccgt tacaatgcct atccttcaga gcaagaaaaa gcgttgctgt cccagcaaac      420

acacctgtct acgctacagg tctgtaactg gttcatcaac gcccgccgca ggctcctccc      480

tgacatgctg agaaaggatg gcaaagatcc aaatcagttc acaatttccc gccgtggggc      540

caagatttct gaaacgagct ctgtggagtc cgtgatgggc atcaaaaact tcatgccagc      600

tctagaggag accccatttc attcctgtac agctgggcca aacccaaccc tagggaggcc      660

actgtctcct aagccgtcat ccccgggatc agttttggct cgtccatcag tgatctgcca      720

taccactgtg actgcattga aagatgtccc tttctctctc tgccagtcgg tcggtgtggg      780

acaaaacaca gatatacagc agatagcggc caaaaacttc acagacacct ctctcatgta      840

cccagaggac acttgtaaat ctggaccaag tacgaataca cagagtggtc ttttcaacac      900

tcctccccct actccaccgg acctcaacca ggacttcagt ggatttcagc ttctagtgga      960

tgttgcactc aaacgggctg cagagatgga gcttcaggca aaacttacag cttaacccat     1020

tttcaagcaa aacagttctc agaaatgtca tgattgccgg ggtgaaggca agagatgaat     1080

tgcattattt tatatatttt ttattaatat ttgcacatgg gattgctaaa acagcttcct     1140

gttactgaga tgtcttcaat ggaatacagt cattccaaga actataaact taaagctact     1200

gtagaaacaa agggttttct tttttaaatg tttcttggta gattattcat aatgtgagat     1260

ggttcccaat atcatgtgat tttttttttc ctccccttcc ctttttttgt tattttttca     1320

gactgtgcaa tacttagaga acctatagca tcttctcatt cccatgtgga acaggatgcc     1380

cacatactgt ctaattaata aattttccat tttttttcaa acaagtatga atctagttgg     1440

ttgatgcctt ttttttcatg acataataaa gtattttctt taaaaaaaaa aaaaaaaa       1498


<210>  1986
<211>  1999
<212>  DNA
<213>  homo sapiens

<400>  1986
ccggagcccc gccagagccc gacttcagcc ccagccagat cccgcgtcaa cggaggcgga       60

acggcggacc ccgtaccctg gcagcatcgg agcaccggcg ggtgaaggca aggtccctgg      120

actggtcata tacctcttgt ggccctggca gaatcaagat gaggccctgt catgcctccc      180

cagtgaggcc tacagtctga gcagacagca tggcctgcca ctggcagtga acaccatgtc      240

tgcaggaggt ggccgggcct ttgcttggca agtgttcccc cccatgccca cttgccgggt      300

ctatggcaca gtggcacacc aagatgggca cctgctggtg ttggggggtt gtggccgggc      360

tggactgccc ctggacactg ctgagacact ggacatggcc tcgcacacat ggctggcact      420

ggcacccctg cccactgccc gggctggtgc agctgcggta gttctgggca agcaggtgct      480

agtggtgggt ggtgtggatg aggtccagag cccggtagct gctgtagagg ccttcctgat      540

ggatgagggc cgctgggagc gtcgggccac cctccctcaa gcagccatgg gggttgcaac      600

tgtggagaga gatggtatgg tgtatgctct ggggggaatg ggccctgaca cggcccccca      660

ggcccaggta cgtgtgtatg agccccgtcg ggactgctgg ctttcgctac cctccatgcc      720

cacaccctgc tatggggcct ccaccttcct gcacgggaac aagatctatg tcctgggggg      780

ccgccagggc aagctcccgg tgactgcttt tgaagccttt gatctggagg cccgtacatg      840

gacccggcat ccaagcctac ccagccgtcg ggcctttgct ggctgcgcca tggctgaagg      900

cagcgtcttt agcctgggtg gcctgcagca gcctgggccc cacaacttct actctcgccc      960

acactttgtc aacactgtgg agatgtttga cctggagcat gggtcctgga ccaaattgcc     1020

ccgcagcctg cgcatgaggg ataagagggc agactttgtg gttgggtccc ttgggggcca     1080

cattgtggcc attgggggcc ttggaaacca gccatgtcct ttgggctctg tggagagctt     1140

tagccttgca cggcggcgct gggaggcatt gcctgccatg cccactgccc gctgctcctg     1200

ctctagtctg caggctgggc cccggctgtt tgttattggg ggtgtggccc agggccccag     1260

tcaagccgtg gaggcactgt gtctgcgtga tggggtctga aggcttggtg ggagctgtcc     1320

actggagcag ctcattgcca gaggcagcta tttctatggc tccttttgct gctgaggaca     1380

ctcactgtgg ctctgtggga tgagagaggc atgggggtga gcacttgaaa cactgccttg     1440

gggccttggg ttaggggagc ctttgtcttt agtgcaggac acacatatgc ttacacctac     1500

ctttatcacc attcgttcat gaatcatgcc tagctccatc cttgccctgg gacctactag     1560

gccttccatc caactgggaa atggggagaa gcaaagctgg cctcatgctc ttcagggtca     1620

gttcctatct ggagttgacc aggcctaccc cagttgccat tcctgaaaaa tctcagctgc     1680

caggctgcct ttagggtccc tgcagaccca ggagagttga gagggtgggg gacacagaga     1740

gaatagagag gatgtgggaa ctgccagagg gccggagcgc aggagttcaa gtggaggaat     1800

gctggctttg agccctctac actgctggtt gtatgacctt ggacaagtca cttcacctct     1860

ctgtgcctca gcatcctcat ctataaatgg ggatctctga aaccttccta ccctacctac     1920

ctcacagggc tgttgtgagg acccagggag tttggatgtg gaagtaaaag tgctgctaaa     1980

acctaaaaaa aaaaaaaaa                                                  1999


<210>  1987
<211>  802
<212>  DNA
<213>  homo sapiens

<400>  1987
aggcgagggg gcggagcaag agaagaaaac acaaagggcc ggaaggaagc cggggagaca       60

ggtggggtac tcgggaagct ggagcgggcc ggcggtgcag tcacggggga gcgaggcctg      120

ctgggcttgg caacgaggga ctcggcctcg gaggcgaccc agaccacaca gacactgggt      180

caaggagtaa gcagaggata aacaactgga aggagagcaa gcacaaagtc atcatggctt      240

cagcgtctgc tcgtggaaac caagataaag atgcccattt tccaccacca agcaagcaga      300

gcctgttgtt ttgtccaaaa tcaaaactgc acatccacag agcagagatc tcaaagatta      360

tgcgagaatg tcaggaagaa agtttctgga agagagctct gcctttttct cttgtaagca      420

tgcttgtcac ccagggacta gtctaccaag gttatttggc agctaattct agatttggat      480

cattgcccaa agttgcactt gctggtctct tgggatttgg ccttggaaag gtatcataca      540

taggagtatg ccagagtaaa ttccattttt ttgaagatca gctccgtggg gctggttttg      600

gtccacagca taacaggcac tgcctcctta cctgtgagga atgcaaaata aagcatggat      660

taagtgagaa gggagactct cagccttcag cttcctaaat tctgtgtctg tgactttcga      720

agttttttaa acctctgaat ttgtacacat ttaaaatttc aagtgtactt taaaataaaa      780

tacttctaat ggaacaaaaa ca                                               802


<210>  1988
<211>  15643
<212>  DNA
<213>  homo sapiens

<400>  1988
aactttaaaa agctgcttcg gacaaaccag agccaggatt tccactgtcg gggacccggg       60

atcggaaggg tctagcccga gggaaatgct ggaagatccc atcggccagt gaccagcaac      120

tttccggcga gattttgacg cggagaactg tgctctgcct cctcttattc tcccaaagct      180

cacgttggcg tcctgccttg cgggggaact cggcgcgctc tctgcctgag cagcgagtga      240

attgaacccc agcccgctcc ggcgcctccg ggctgatgag tgtcgctctc cgcccgtcca      300

tctctttttc ccggaggtaa aggcccgcgg tcccccacct tcagtgcgcc cgggttccaa      360

gcgccggagc cagcgttttg gcggagccgc ttcttggatg ctgaaggctg ggctcctcca      420

tcgtgggtgc cgaggcggcg atgggtgtcc tcaaagtgtg gctcgggctg gccctagcgt      480

tggcggaatt tgcagtattg cctcatcatt ccgaaggtgc ttgtgtctat caggattcct      540

tgttggcgga tgccacaatt tggaagcccg attcatgcca gagctgccgt tgccatggtg      600

atattgttat ctgcaaacct gctgtttgca gaaaccctca atgtgccttt gagaagggag      660

aagtgcttca aatagctgcc aaccaatgct gtcctgagtg tgttttgagg actccaggat      720

cttgccatca tgaaaagaaa atccatgagc atgggacaga atgggcctct tctccatgta      780

gtgtgtgctc ttgcaatcat ggggaagtcc gatgtacccc ccaaccatgc ccaccgctgt      840

catgtggaca ccaggagctg gcattcatcc ctgaaggaag ctgctgccca gtttgtgtgg      900

gccttgggaa accctgttcc tatgaaggcc atgtgtttca ggatggggag gactggcggc      960

tgagccggtg tgccaaatgt ctgtgtagaa atggggttgc ccagtgcttc acagctcagt     1020

gtcagcctct attttgtaac caggatgaga ctgtagtccg agtccctgga aaatgttgcc     1080

cgcagtgctc tgcaagatcc tgctctgcag ctggccaagt atacgagcat ggtgagcagt     1140

ggagcgaaaa tgcctgcacc acgtgtatat gtgaccgggg tgaggtcagg tgtcacaagc     1200

aggcctgcct gcccctgaga tgcggaaagg gtcagagcag ggctcggcgt catgggcaat     1260

gctgtgagga atgtgtgtct cctgccggga gctgctccta tgatggagtt gtgcggtacc     1320

aggacgaaat gtggaagggc tcggcctgtg agttctgcat gtgtgatcat ggccaagtga     1380

cctgccagac tggagagtgt gccaaagtgg agtgtgcccg ggatgaagaa ttaattcact     1440

tagatggaaa gtgttgtcct gaatgcattt caaggaatgg ttattgtgtt tatgaagaaa     1500

ctggagaatt tatgtcatca aatgctagtg aagttaaacg tattccagag ggagagaagt     1560

gggaagatgg cccttgcaag gtgtgtgagt gccgaggggc tcaggtaact tgctacgagc     1620

cctcttgccc accatgtcca gtgggcacac tggccttaga ggtgaaggga cagtgctgtc     1680

cagactgcac atcagttcat tgccatccag attgtttgac atgctctcag tctccagacc     1740

actgtgacct ctgccaagat cctaccaagt tactgcagaa tggatggtgt gtgcacagct     1800

gtggactggg tttttaccaa gctggcagtc tctgtttagc ctgccagccc cagtgctcca     1860

cgtgtaccag tgggctggag tgctcatcct gccagcctcc cctgctgatg cggcacgggc     1920

agtgtgtgcc tacctgtggg gacggcttct accaagatcg ccattcctgt gcagtctgcc     1980

atgagtcctg tgcaggttgc tggggcccaa cggagaagca ctgcttggcc tgcagagatc     2040

ccctccacgt gctgagagat ggcggctgtg agagcagctg tggaaaaggc ttctacaaca     2100

ggcagggcac ctgtagcgct tgtgaccaat cctgtgacag ttgtggcccc agtagcccca     2160

ggtgtcttac ctgtactgag aagacagtgc tgcatgatgg gaaatgcatg tctgaatgcc     2220

ctggcgggta ctatgctgat gccactggca ggtgcaaagt ttgtcataac tcatgtgcca     2280

gctgctctgg gcccacaccc tctcactgta cagcctgcag cccccccaag gctctgcgtc     2340

aaggccactg tctgccccgc tgtggagagg gtttctactc tgaccatgga gtctgcaaag     2400

cctgtcactc ctcctgcctg gcttgtatgg gtcccgcacc ctctcactgt actgggtgta     2460

agaagccaga ggaaggactg caagtggagc agctgtctga cgtgggcatc ccctctggcg     2520

agtgtctagc ccagtgtaga gcccattttt acttggagag cactggcata tgtgaagctt     2580

gccaccagtc ctgtttcaga tgtgcaggga aaagcccaca taactgcaca gactgtgggc     2640

cttcccatgt gctgttggat gggcagtgcc tctcccagtg cccagatggc tactttcacc     2700

aggaaggtag ttgcacagag tgtcacccaa cctgcaggca gtgtcatggg ccgttggagt     2760

ctgactgcat ctcctgttac cctcacatct ctcttaccaa tggtaactgc aggaccagct     2820

gcagggaaga gcagttcctc aacctcgtgg gatactgtgc tgactgccat cacctgtgcc     2880

agcactgtgc agctgatctc cacaacactg ggagcatctg cctcaggtgc cagaatgccc     2940

actacctgct gctcggggac cactgtgttc ctgactgccc ttcaggatac tatgcagaga     3000

gaggagcttg taaaaaatgc cactcctcct gcagaacctg ccagggcaga ggacctttct     3060

cctgctcctc atgtgacacc aacctcgtgc tgtcccacac tggcacctgc agcaccacct     3120

gcttccctgg gcactatctt gatgacaatc atgtttgcca gccatgcaac acacactgtg     3180

gaagctgtga ttcacaggcc agctgtacct cctgccgaga tccaaacaag gttctgctct     3240

ttggggaatg tcaatacgag agctgcgccc cacagtacta tcttgacttc tccaccaaca     3300

cgtgcaaaga gtgtgattgg agctgcagtg catgcagtgg gcccctgaaa acagactgcc     3360

tgcagtgcat ggatggctat gttctccagg atggggcctg cgtggagcag tgcttgtcat     3420

cattttacca ggactcgggc ctctgcaaga actgtgacag ctactgtctc cagtgccaag     3480

gtccccatga gtgtacccgc tgcaaagggc catttctcct cttggaagcc cagtgtgtcc     3540

aggaatgtgg gaaggggtac tttgcagatc atgcaaagca caaatgcaca gcctgccctc     3600

aggggtgctt gcagtgcagc cacagggacc gttgtcacct ctgtgaccat gggttctttc     3660

tgaagagtgg cctctgtgtt tacaactgtg ttcctggctt ttctgtccac acctctaatg     3720

aaacatgttc tggcaaaata cacaccccta gtcttcatgt gaatggttcc ctgatcctcc     3780

caattggttc aataaagcca ctggattttt ccctcctgaa tgtccaagac caggagggta     3840

gggtcgaaga tctcctattt catgttgtga gcactcccac caatggtcag ctagtgctct     3900

caagaaatgg aaaagaggtt cagctggaca aggctggccg ttttagctgg aaagatgtga     3960

acgagaagaa agtgcgtttt gtgcacagca aagaaaaact caggaaaggt taccttttcc     4020

tgaaaattag tgaccagcag ttcttctctg agccacagct gatcaacata caagcatttt     4080

caacacaggc cccctatgtg ctgagaaatg aagttctcca cattagcaga ggagagaggg     4140

caaccatcac cacccagatg cttgacatcc gagatgatga caacccacag gatgtggtca     4200

ttgaaataat cgatcctcca cttcatggcc aattgcttca gacacttcag tccccggcaa     4260

cccctatcta tcaattccag ctggatgaac tctctagagg ccttctccac tatgctcatg     4320

atggttcaga cagcacatcc gatgttgcag tcttgcaggc caatgatgga cactccttcc     4380

ataatatact gttccaagtg aagaccgtgc ctcagaatga caggggtctt cagcttgtgg     4440

ctaattcgat ggtgtgggtt ccagaagggg ggatgctgca gatcaccaac agaatcttac     4500

aggccgaggc tcctggtgcc agtgctgaag aaatcatcta caagattaca caagactacc     4560

cccagtttgg ggaggtggtc cttctagtga atatgcctgc agacagccct gcagatgaag     4620

ggcagcacct gcctgatggg aggacagcta cccccaccag caccttcacc cagcaggaca     4680

tcaatgaagg catcgtatgg tacaggcact caggagcccc agcccagagc gactccttcc     4740

gcttcgaggt gtccagtgcc tccaatgccc agacccgcct ggagagccac atgttcaaca     4800

tcgcgatctt accacagaca cctgaagcac ctaaagtgtc tctggaagca tctctccata     4860

tgactgctag agaagatggc ctgactgtta ttcagcctca ttccctctcc ttcataaact     4920

ctgagaagcc aagtggaaag attgtctaca acatcactct acctctgcat ccaaatcaag     4980

gtatcatcga gcaccgggac caccctcact ctcctatccg gtatttcacg caagaggata     5040

ttaaccaggg caaagtcatg taccgccctc ccccggcagc accccacctc caggagctca     5100

tggccttctc gttcgctggt ctcccagaat cagtgaaatt ccacttcaca gtttcagatg     5160

gagaacacac aagtccggag atggtcctca ccattcactt acttcccagt gatcagcaac     5220

tgccagtgtt ccaggtcaca gctccacggc tggcggtcag cccaggaggc agcacttctg     5280

taggacttca ggtggtagta agagatgctg agacagcgcc caaagaactc ttctttgagc     5340

ttcggagacc tccacagcat ggtgtgcttc ttaagcatac agctgagttc cgaaggccga     5400

tggccacagg tgacactttc acctatgagg atgttgagaa aaatgctcta cagtatatac     5460

atgatggttc ctctacccgg gaagacagca tggagatctc agtcacagat ggcctcacag     5520

tgacaatgct ggaggtgaga gtagaggtgt ccctgtcaga agaccgaggg cctcgactgg     5580

ctgctggctc ctctctgagc attactgttg ccagtaaaag cacagccata atcactaggt     5640

cacaccttgc ttacgtggat gattcttccc ccgacccaga gatctggatt cagttaaatt     5700

atctgccctc atatggtact ctcttaagaa tctcaggatc tgaggtggaa gagctctcag     5760

aagtttccaa tttcacaatg gaagacatca ataacaagaa aatcagatac tcagctgtgt     5820

ttgaaactga tggtcatctg gttactgata gcttctattt ctctgtctct gacatggacc     5880

acaaccatct ggataatcag atatttacca tcatgatcac tcctgctgaa aatccacctc     5940

cagtcattgc ttttgctgac cttatcacgg ttgatgaggg agggagagca ccactctcat     6000

ttcaccattt ttttgctact gatgatgatg acaacctcca gagagatgcc atcattaaac     6060

taagtgctct gcccaaatat ggctgcattg agaacacagg aacaggtgat cgttttggcc     6120

ctgaaactgc cagtgaccta gaggcatcat ttcctattca agacgtcctg gaaaactaca     6180

tttactactt tcagagtgtt catgaaagca ttgagccaac ccatgatatt tttagttttt     6240

atgtgagtga tggaaccagt cgttcagaaa ttcacagcat caatatcacc attgagagga     6300

agaacgatga gcctcccagg atgaccttgc agcccctcag agtgcagctg agctcgggag     6360

tggtgataag caattcttct ttgagcctgc aagacctgga caccccagat aatgagctca     6420

tttttgtatt gacaaaaaag cctgaccacg gtcatgtact ctggaggcaa actgcttctg     6480

agcctctgga gaatgggaga gttttagtcc agggctcaac cttcacctac caggatatcc     6540

tagctgggct ggttgggtat gtgcctagtg tccctggcat ggtcgtggat gagttccagt     6600

tctccctcac tgatggcctc cacgtggaca cagggaggat gaagatctac acagaactgc     6660

ctgcaagtga cacacctcac ttggctataa accaaggcct acagctctca gcagggtctg     6720

tagcacgcat cacagaacag cacttgaaag tgacagatat tgactcagat gaccatcagg     6780

ttatgtacat catgaaggaa gatcctggtg cagggcgcct gcagatgatg aagcatggca     6840

acctggagca aatttctatt aaaggcccca tccgaagttt cacccaggca gacattagcc     6900

aaggccacgt agaatatagt catggaacag gagaacctgg agggagcttt gcttttaaat     6960

ttgatgtggt tgatggagaa ggcaacagat tgattgacaa gtcattttcc atcagcattc     7020

tagaagacaa atccccacca gtcatcacca ccaataaagg actggtcttg gatgaaaact     7080

cagtgaagaa aatcaccacc ctgcagctgt ctgccactga ccaggacagt gggcctacag     7140

aattgatcta cagaatcacc agacagcccc agctgggcca cttggaacat gcagcatcac     7200

caggtatcca gattagttcc tttactcaag ctgatctgac ttcacgaaat gttcagtatg     7260

tccattctag tgaggctgag aaacattcag atgccttcag ctttacactg tctgatggag     7320

tcagtgaggt gactcagact ttccatatca ctcttcaccc tgtcgatgat tcgctgcccg     7380

tcgtacagaa cttaggaatg cgggtgcagg agggcatgag gaagaccatc acagagtttg     7440

agcttaaggc ggtggatgct gacacagagg ccgagtctgt cacattcacc atcgtgcagc     7500

ctccacgcca tggcaccatc gagcgaacca gcaatgggca gcatttccac ctcacctcca     7560

ccttcaccat gaaagatatc taccagaacc gggtcagcta cagccatgac ggcagtaact     7620

ccctcaagga ccggttcacc ttcactgttt ctgatgggac aaaccccttc tttatcattg     7680

aggaaggggg aaaagagatt atgacagcag cacctcagcc gttccgagta gacatcctcc     7740

cggtagatga tggcacgcct agaattgtca ccaacctggg actccagtgg ctggaataca     7800

tggatggcaa ggcaaccaac ctgatcacca agaaggaact gctgaccatg gacccagaca     7860

ccgaggacgc gcagcttgtc tatgagataa cgacgggccc taagcatggc tttgtggaga     7920

acaagctgca gcctggcaga gctgctgcca ctttcaccca ggaggatgtg aacttggggt     7980

tgattcgtta tgtgttgcac aaggagaaga tccgtgagat gatggatagt tttcagtttc     8040

tggtgaaaga cagtaaaccc aatgtggtca gcgacaatgt cttccatatc cagtggtcac     8100

tcatcagctt taaatatacc agctacaatg tcagtgagaa ggcagggtct gtcagtgtca     8160

cggtgcagag gactgggaac ctgaaccaat atgccatcgt cctgtgtcgc accgagcaag     8220

gcaccgccag ctccagctcc agggtcagct cccaacctgg gcaacaggac tatgtagagt     8280

atgctggcca ggtccagttt gatgagcgag aggacaccaa gtcctgcacc attgtcatca     8340

acgatgatga cgtgtttgaa aatgttgaga gtttcactgt ggagctcagc atgccagctt     8400

atgccctgtt aggggaattc acccaggcga aggtcattat caacgatacc gaggatgaac     8460

ccacattaga gtttgacaag aagatctact gggttaacga gagcgctggt tttctgtttg     8520

cacctattga aagaaaagga gatgcaagca gcattgtatc tgcaatttgc tacacagtcc     8580

ctaagtcagc tatgggaagt agcctctatg ctctagaatc aggctctgat tttaaatcta     8640

gagggatgtc tgccgcgagt cgtgtgatat tcgggcctgg tgtgaccatg tccacctgtg     8700

atgtcatgct tattgatgac agcgagtatg aagaggaaga agagtttgag attgccttgg     8760

cagatgcctc tgacaatgcc cgcattggaa gggtggcgac agccaaggtg ctcattagtg     8820

gtcccaacga tgcctcgact gtgtccctgg gcaacacggc tttcactgtc agtgaggacg     8880

caggcacagt aaagattcca gttatccgcc atggtactga cctctctact ttcgcatctg     8940

tctggtgtgc aacgcggccc tcagacccag cttctgccac accaggagtt gactacgttc     9000

ccagctctcg gaaggtggaa tttgggcctg gtgtcattga acagtattgc accttgacta     9060

tcttggatga cactcagtat ccggtaattg aaggactgga gacatttgtg gttttcctca     9120

gctcagcaca aggagccgaa ctgaccaaac ccttccaggc agtcattgca attaatgaca     9180

cattccaaga tgtgcccagc atgcagtttg ccaaggattt gctcctagtg aaggagaagg     9240

agggtgtcct gcatgtccct atcactcgga gcggagacct gagctatgag tcatcagtga     9300

ggtgctatac tcagagccat tccgctcagg tcatggagga ctttgaggag agacaaaatg     9360

cagactcttc acggattaca tttctcaaag gggacaaagt gaagaactgt acggtctata     9420

tccacgatga ctccatgttt gagccagagg aacagttcag ggtctacctc ggccttcctc     9480

ttggaaacca ctggagtgga gctagaattg gaaagaataa catggccacc atcaccatat     9540

ccaatgatga agatgccccc accattgagt ttgaagaagc tgcataccaa gtccgggaac     9600

ccgcaggccc agatgccatt gcgattctga acatcaaggt gatccgcaga ggggatcaga     9660

acaggacctc caaggttcgc tgcagcacgc gggatggctc tgcccagtct ggtgtggatt     9720

attacccaaa gagccgagtc ttgaagttca gtcccggtgt ggatcatatc ttttttaaag     9780

ttgagatcct gtccaatgaa gaccgggaat ggcatgaatc tttctcacta gtccttggcc     9840

cagatgaccc agtggaagca gttcttgggg atgtgactac tgccacggtg acaattctag     9900

accaggaggc agcagggagc ctcatattgc cagcaccacc cattgtggtc acacttgctg     9960

actatgacca tgtggaagaa gttaccaagg aaggagtcaa gaaatccccc tccccaggct    10020

acccactggt ctgtgtcacc ccctgcgacc ctcatttccc cagatacgct gtcatgaagg    10080

agcgctgcag tgaggccggc atcaaccaga catctgtgca gttcagctgg gaagtggctg    10140

cccccactga tggcaatggg gcccggtctc cctttgaaac catcactgac aacacaccat    10200

tcaccagtgt caaccacatg gtcctggaca gcatttactt cagccggagg ttccatgtgc    10260

gttgtgtggc caaggctgtg gacaaggtgg gccatgtggg gaccccctta aggagcaaca    10320

ttgttaccat tggaacagac agtgctatct gccacacacc agtggtggct gggacatcca    10380

gaggcttcca ggctcagtcc ttcatcgcaa ccttgaaata cctggatgtc aaacataagg    10440

agcatccgaa cagaatccac atttcggtgc agatcccaca ccaggatgga atgctgcccc    10500

ttatctccac catgccgttg cacaacttac attttctact gtctgagtcc atctacagac    10560

accagcacgt ctgctccaat ttagttacca cctatgacct gagaggcatc tcagaggcag    10620

ggttcctgga tgatgtggtc tatgatagca ctgccctggg gcctggctac gatcgcccct    10680

tccagtttga ccccagcgtg cgagagccga agaccatcca gctctacaaa cacctgaacc    10740

tgaagagctg cgtgtggacc tttgatgctt attatgacat gactgagctg attgacgtct    10800

gtgggggctc tgtaaccgct gacttccagg tgagggactc tgcccagtcc ttcttgacag    10860

tgcacgtgcc tctatatgtg tcctacatct atgtgacagc ccccaggggc tgggcctcct    10920

tggagcacca caccgagatg gagttttctt tcttctatga cactgttctc tggagaacag    10980

gaatccagac agacagcgtg ctctctgcaa ggcttcagat aataagaatc tacattcgag    11040

aggatggccg tcttgtcatt gaattcaaga cccatgccaa attcagagga cagtttgtga    11100

tggagcatca cactctccca gaagtgaaat ctttcgtatt gactccagac cacctaggag    11160

gaattgaatt tgacttgcag ctattatgga gcgctcagac ttttgattct ccacatcaac    11220

tctggagagc cacaagctct tataacagga aggactactc aggagagtac accatctacc    11280

tgatcccttg cacagtgcag cccacacagc catgggttga cccaggagag aagcctttgg    11340

cctgcactgc acatgcccca gaaagattcc tgatacccat tgcattccag cagaccaacc    11400

gccctgtgcc agttgtgtat tcacttaaca ctgaatttca gctctgcaat aatgagaagg    11460

tgttcctaat ggatcccaat acatctgata tgtcactagc agaaatggat tacaaaggag    11520

ccttttcaaa aggtcaaatc ctttatggcc gagtactttg gaatccagaa caaaatctta    11580

attctgctta caaactccag ctggagaaag tctatctttg tacgggcaag gatggttatg    11640

tgcctttctt tgatcccacg gggacaatct acaatgaagg gccccagtat ggatgcattc    11700

agccaaacaa acacctaaaa cacagattcc tgctgttgga ccgcaatcag ccagaggtaa    11760

ctgataagta cttccatgat gtgccttttg aggctcactt tgcctctgag ttgcctgatt    11820

tccatgtggt cagtaacatg ccaggtgtgg atggatttac tctaaaagta gatgcactct    11880

ataaggtgga agcaggacac cagtggtatc tccaggtcat ctacatcatt ggccctgaca    11940

ccatctcagg gccccgggtc cagcgctctc tcacagctcc actcagacgc aaccgaaggg    12000

acctggtaga gcccgatggc cagctgatcc ttgatgattc cctcatctat gacaatgaag    12060

gagaccaagt caagaatggc accaatatga agtccctgaa tctggagatg caagagttgg    12120

cggtagctgc gtccctgtca cagactgggg cgtccattgg cagtgccctg gctgcaatca    12180

tgcttctact tctggtgttt ttggtggctt gttttatcaa caggaaatgc cagaaacaga    12240

ggaagaagaa gcccgcagag gacattttgg aagaatatcc tctgaatacc aaggtagaag    12300

tgcccaagag gcacccggac cgggtggaga agaacgtgaa tagacactac tgcactgtgc    12360

ggaacgtcaa catcctgagt gagcctgagg cggcttacac gttcaaaggt gctaaagtca    12420

aaagactgaa tctagaagtc agagttcaca acaatttaca agatggaaca gaagtttaat    12480

ggaggagacc tatgtgtatt tttttctaaa atcattttta taaaatgggg ggaaatactg    12540

gtatttttat aatctcgcag ataaaaaagg gaaaactata gctttgagtg gcagacagca    12600

cacatcacat gcatcaactc acaactgagc tacctcattc agcaaagaac cactgagaac    12660

cccagagtat tacagttatt tccgtagatc cctttaatag tgtcaacaac tgtacacagc    12720

tccttctgta aggctggtct tagaaaacaa gtactttagt atcaggacag gagttgaaca    12780

attaggttag cagatggaga tgagaggact gggtagagta ccatggcaga tctcagagag    12840

aagaagtagg tacgggcctt tggttccctc ccccagcccc agctttctcc tacagggctt    12900

ttcctgagtc cccagacagc agagtatgaa ctgctgacac ccagattcca ttaaaaattc    12960

tgctaatcga cacaacacat atatttgctc atgatttcac ttgacagcgt atgctccttg    13020

gcctctaatt gtactttgct tttccagagc cctttttacc tggggatttc agtgtgctta    13080

agtaaaatcc tctgaaaacc acgggagcct ctgcctcctc agccacagag aactccctcc    13140

tacaaagggg gagactgaaa cccgagttaa ggaggggcct ggcaggcgta tcagagcaca    13200

ttagtgatgc ccttcacccc agggaggtgt ctgttcccaa ctagtttatg tggcactgag    13260

acatccatcc ctgaccaagg atgctgcgaa acaggatcaa tgtactacgg ccttttaatt    13320

caacattgcc ataaatgctt taaagaaaac ccaccacact ttcctcctac tccggtcttt    13380

gcccgttcct gtaacagaca atcccatgtc ctaggtatgg ttttttattc tgttagtgct    13440

tcgggaaagt aagtgattca tttgaataag gcaaattagg agaaagccca ggttggggtg    13500

aaatcagact taacagatac atgctggttc tccttgctgt gtgtgacaca gcagacagag    13560

gcactattcc tggtgcagta tttcagggat ttctctttga ggggttcttt tctggtagct    13620

caggcaatta tttttaccat atcagcacat gacaaggcca tgaacacatg gctctaaaat    13680

aatttagtgt tcaagtatca gcttaactat tttgtgtagg ctacacacag cttgcttttg    13740

tttctcttct gtttctgcct tattggcgga aacataagcg tgcatgccat gttgttttga    13800

attggaggca caatttcatt attcgagagt aaaagacatg tcctcttctg atgcatggca    13860

caccatagtc accaagcaaa taacagagcc ttcacattgt gtaatatttg tatgagaatg    13920

actcaagctc tttgagaaca ttccaaacta gtaacatttc gctactaaaa gctagaaagg    13980

atgaactgtg aaaggttcta ggcagctctg tgagactcca agctccttga aagtaggacc    14040

tttgtgagcc acgcctttca ttcttcaaca gtgccttgca tgtaacaagc actccagaaa    14100

tgtttgttga atgaatgaat ggtgtcatgg gtgaatgatg gggagtaaat ttaggaaggg    14160

gaagtgagag agtatggtgg caatatcaca agggaggaga gaggaaaaca attatcttct    14220

ctacttggat tatgagataa ccttttcttg gaggaaagaa acaccgcttt acaaaggcat    14280

gactctggcg gtggtcctaa ggaagcatga gcagaaaatt cataaaaatg tatcatcagc    14340

aggagatgag actatgaatt ggcatccaga acaggagatt tagagcaaaa tctaatttag    14400

cattctgaga tgagtgtcag gttttcagga gagaatgagt tggggtgagc ccagagtctg    14460

aaactcctga ctggtcaggt gctacttaag accagcttgg gcaattcagg gcagaactcc    14520

tgtatcagcc tcatggacac ccagaattgg tatctcatgg ctggagagct gatcagccag    14580

gcacagaatc tccagaacaa cctagagagt gaatgctaat ttgtagagcg aacttccatt    14640

tggcccatta tttgtaactg tgtaactgct ccaagtgcca gaatgcttac acgttaaagc    14700

agcacctttc catttgccca catattcttc ttgcacaccc cttccattac tgctgaatag    14760

gacattgcat gggaagagta cagaggtggc agaatgaagc tagagtggga aggactaaag    14820

actgagcccc agagtgctcc cagcaaccgc cacgtacaag gtctgaaatg acaagggcaa    14880

gagtgagata ggaaactgtg tgtgaaagga aagcccttgc agtatttctg cctccctttc    14940

tttctgcctt tcaccccact aaatgtatgt tattgaatgc cagtacttct ctagtggatg    15000

cacacttgtt aaatagtgtt aagagatgtg gagatgagat ataccccttt gatgtagaat    15060

tattcatttg gtttgtttca tacttcatta taggaatcaa gtaatttgat gactaatgtg    15120

gattatattt cagtcaaagc tctgctttca atttctctga tttgctcact aatgccttgt    15180

gtgtgtttta ctaacctttt atatcttgcc ttcaagtgag aaggaacaaa caactctcag    15240

tggttactac ttgcttttat atgctggctg tgaaggttaa aagaaagaat ggtctgtacc    15300

attctgcttt gctgcccttt tattgtaccc caggcctcct agaggactcc tgcagattct    15360

attgttgggt gggaaatagt gttggaatgt gtttgcacag tcttatgata ttcagtctca    15420

gtctgctata ggtatttgtt attcttggat actacacacc tgctcagact gagtaaacat    15480

ttgtggtgct gtcaacctga tttcttgact ctcaaatgat ttttgtattt ccaatatgaa    15540

tttgtgtgtt atgaatttct gatttctcca atagtatatg ccactatata aatttgtatt    15600

aataaatgac agtcttgttg gtttaaaaaa aaaaaaaaaa aaa                      15643


<210>  1989
<211>  7245
<212>  DNA
<213>  homo sapiens

<400>  1989
aactttaaaa agctgcttcg gacaaaccag agccaggatt tccactgtcg gggacccggg       60

atcggaaggg tctagcccga gggaaatgct ggaagatccc atcggccagt gaccagcaac      120

tttccggcga gattttgacg cggagaactg tgctctgcct cctcttattc tcccaaagct      180

cacgttggcg tcctgccttg cgggggaact cggcgcgctc tctgcctgag cagcgagtga      240

attgaacccc agcccgctcc ggcgcctccg ggctgatgag tgtcgctctc cgcccgtcca      300

tctctttttc ccggaggtaa aggcccgcgg tcccccacct tcagtgcgcc cgggttccaa      360

gcgccggagc cagcgttttg gcggagccgc ttcttggatg ctgaaggctg ggctcctcca      420

tcgtgggtgc cgaggcggcg atgggtgtcc tcaaagtgtg gctcgggctg gccctagcgt      480

tggcggaatt tgcagtattg cctcatcatt ccgaaggtgc ttgtgtctat caggattcct      540

tgttggcgga tgccacaatt tggaagcccg attcatgcca gagctgccgt tgccatggtg      600

atattgttat ctgcaaacct gctgtttgca gaaaccctca atgtgccttt gagaagggag      660

aagtgcttca aatagctgcc aaccaatgct gtcctgagtg tgttttgagg actccaggat      720

cttgccatca tgaaaagaaa atccatgagc atgggacaga atgggcctct tctccatgta      780

gtgtgtgctc ttgcaatcat ggggaagtcc gatgtacccc ccaaccatgc ccaccgctgt      840

catgtggaca ccaggagctg gcattcatcc ctgaaggaag ctgctgccca gtttgtgtgg      900

gccttgggaa accctgttcc tatgaaggcc atgtgtttca ggatggggag gactggcggc      960

tgagccggtg tgccaaatgt ctgtgtagaa atggggttgc ccagtgcttc acagctcagt     1020

gtcagcctct attttgtaac caggatgaga ctgtagtccg agtccctgga aaatgttgcc     1080

cgcagtgctc tgcaagatcc tgctctgcag ctggccaagt atacgagcat ggtgagcagt     1140

ggagcgaaaa tgcctgcacc acgtgtatat gtgaccgggg tgaggtcagg tgtcacaagc     1200

aggcctgcct gcccctgaga tgcggaaagg gtcagagcag ggctcggcgt catgggcaat     1260

gctgtgagga atgtgtgtct cctgccggga gctgctccta tgatggagtt gtgcggtacc     1320

aggacgaaat gtggaagggc tcggcctgtg agttctgcat gtgtgatcat ggccaagtga     1380

cctgccagac tggagagtgt gccaaagtgg agtgtgcccg ggatgaagaa ttaattcact     1440

tagatggaaa gtgttgtcct gaatgcattt caaggaatgg ttattgtgtt tatgaagaaa     1500

ctggagaatt tatgtcatca aatgctagtg aagttaaacg tattccagag ggagagaagt     1560

gggaagatgg cccttgcaag gtgtgtgagt gccgaggggc tcaggtaact tgctacgagc     1620

cctcttgccc accatgtcca gtgggcacac tggccttaga ggtgaaggga cagtgctgtc     1680

cagactgcac atcagttcat tgccatccag attgtttgac atgctctcag tctccagacc     1740

actgtgacct ctgccaagat cctaccaagt tactgcagaa tggatggtgt gtgcacagct     1800

gtggactggg tttttaccaa gctggcagtc tctgtttagc ctgccagccc cagtgctcca     1860

cgtgtaccag tgggctggag tgctcatcct gccagcctcc cctgctgatg cggcacgggc     1920

agtgtgtgcc tacctgtggg gacggcttct accaagatcg ccattcctgt gcagtctgcc     1980

atgagtcctg tgcaggttgc tggggcccaa cggagaagca ctgcttggcc tgcagagatc     2040

ccctccacgt gctgagagat ggcggctgtg agagcagctg tggaaaaggc ttctacaaca     2100

ggcagggcac ctgtagcgct tgtgaccaat cctgtgacag ttgtggcccc agtagcccca     2160

ggtgtcttac ctgtactgag aagacagtgc tgcatgatgg gaaatgcatg tctgaatgcc     2220

ctggcgggta ctatgctgat gccactggca ggtgcaaagt ttgtcataac tcatgtgcca     2280

gctgctctgg gcccacaccc tctcactgta cagcctgcag cccccccaag gctctgcgtc     2340

aaggccactg tctgccccgc tgtggagagg gtttctactc tgaccatgga gtctgcaaag     2400

cctgtcactc ctcctgcctg gcttgtatgg gtcccgcacc ctctcactgt actgggtgta     2460

agaagccaga ggaaggactg caagtggagc agctgtctga cgtgggcatc ccctctggcg     2520

agtgtctagc ccagtgtaga gcccattttt acttggagag cactggcata tgtgaagctt     2580

gccaccagtc ctgtttcaga tgtgcaggga aaagcccaca taactgcaca gactgtgggc     2640

cttcccatgt gctgttggat gggcagtgcc tctcccagtg cccagatggc tactttcacc     2700

aggaaggtag ttgcacagag tgtcacccaa cctgcaggca gtgtcatggg ccgttggagt     2760

ctgactgcat ctcctgttac cctcacatct ctcttaccaa tggtaactgc aggaccagct     2820

gcagggaaga gcagttcctc aacctcgtgg gatactgtgc tgactgccat cacctgtgcc     2880

agcactgtgc agctgatctc cacaacactg ggagcatctg cctcaggtgc cagaatgccc     2940

actacctgct gctcggggac cactgtgttc ctgactgccc ttcaggatac tatgcagaga     3000

gaggagcttg taaaaaatgc cactcctcct gcagaacctg ccagggcaga ggacctttct     3060

cctgctcctc atgtgacacc aacctcgtgc tgtcccacac tggcacctgc agcaccacct     3120

gcttccctgg gcactatctt gatgacaatc atgtttgcca gccatgcaac acacactgtg     3180

gaagctgtga ttcacaggcc agctgtacct cctgccgaga tccaaacaag gttctgctct     3240

ttggggaatg tcaatacgag agctgcgccc cacagtacta tcttgacttc tccaccaaca     3300

cgtgcaaaga gtgtgattgg agctgcagtg catgcagtgg gcccctgaaa acagactgcc     3360

tgcagtgcat ggatggctat gttctccagg atggggcctg cgtggagcag tgcttgtcat     3420

cattttacca ggactcgggc ctctgcaaga actgtgacag ctactgtctc cagtgccaag     3480

gtccccatga gtgtacccgc tgcaaagggc catttctcct cttggaagcc cagtgtgtcc     3540

aggaatgtgg gaaggggtac tttgcagatc atgcaaagca caaatgcaca gcctgccctc     3600

aggggtgctt gcagtgcagc cacagggacc gttgtcacct ctgtgaccat gggttctttc     3660

tgaagagtgg cctctgtgtt tacaactgtg ttcctggctt ttctgtccac acctctaatg     3720

aaacatgttc tggcaaaata cacaccccta gtcttcatgt gaatggttcc ctgatcctcc     3780

caattggttc aataaagcca ctggattttt ccctcctgaa tgtccaagac caggagggta     3840

gggtcgaaga tctcctattt catgttgtga gcactcccac caatggtcag ctagtgctct     3900

caagaaatgg aaaagaggtt cagctggaca aggctggccg ttttagctgg aaagatgtga     3960

acgagaagaa agtgcgtttt gtgcacagca aagaaaaact caggaaaggt taccttttcc     4020

tgaaaattag tgaccagcag ttcttctctg agccacagct gatcaacata caagcatttt     4080

caacacaggc cccctatgtg ctgagaaatg aagttctcca cattagcaga ggagagaggg     4140

caaccatcac cacccagatg cttgacatcc gagatgatga caacccacag gatgtggtca     4200

ttgaaataat cgatcctcca cttcatggcc aattgcttca gacacttcag tccccggcaa     4260

cccctatcta tcaattccag ctggatgaac tctctagagg ccttctccac tatgctcatg     4320

atggttcaga cagcacatcc gatgttgcag tcttgcaggc caatgatgga cactccttcc     4380

ataatatact gttccaagtg aagaccgtgc ctcagaatga caggggtctt cagcttgtgg     4440

ctaattcgat ggtgtgggtt ccagaagggg ggatgctgca gatcaccaac agaatcttac     4500

aggccgaggc tcctggtgcc agtgctgaag aaatcatcta caagattaca caagactacc     4560

cccagtttgg ggaggtggtc cttctagtga atatgcctgc agacagccct gcagatgaag     4620

ggcagcacct gcctgatggg aggacagcta cccccaccag caccttcacc cagcaggaca     4680

tcaatgaagg catcgtatgg tacaggcact caggagcccc agcccagagc gactccttcc     4740

gcttcgaggt gtccagtgcc tccaatgccc agacccgcct ggagagccac atgttcaaca     4800

tcgcgatctt accacagaca cctgaagcac ctaaagtgtc tctggaagca tctctccata     4860

tgactgctag agaagatggc ctgactgtta ttcagcctca ttccctctcc ttcataaact     4920

ctgagaagcc aagtggaaag attgtctaca acatcactct acctctgcat ccaaatcaag     4980

gtatcatcga gcaccgggac caccctcact ctcctatccg gtatttcacg caagaggata     5040

ttaaccaggg caaagtcatg taccgccctc ccccggcagc accccacctc caggagctca     5100

tggccttctc gttcgctggt ctcccagaat cagtgaaatt ccacttcaca gtttcagatg     5160

gagaacacac aagtccggag atggtcctca ccattcactt acttcccagt gatcagcaac     5220

tgccagtgtt ccaggtcaca gctccacggc tggcggtcag cccaggaggc agcacttctg     5280

taggacttca ggtggtagta agagatgctg agacagcgcc caaagaactc ttctttgagc     5340

ttcggagacc tccacagcat ggtgtgcttc ttaagcatac agctgagttc cgaaggccga     5400

tggccacagg tgacactttc acctatgagg atgttgagaa aaatgctcta cagtatatac     5460

atgatggttc ctctacccgg gaagacagca tggagatctc agtcacagat ggcctcacag     5520

tgacaatgct ggaggtgaga gtagaggtgt ccctgtcaga agaccgaggg cctcgactgg     5580

ctgctggctc ctctctgagc attactgttg ccagtaaaag cacagccata atcactaggt     5640

cacaccttgc ttacgtggat gattcttccc ccgacccaga gatctggatt cagttaaatt     5700

atctgccctc atatggtact ctcttaagaa tctcaggatc tgaggtggaa gagctctcag     5760

aagtttccaa tttcacaatg gaagacatca ataacaagaa aatcagatac tcagctgtgt     5820

ttgaaactga tggtcatctg gttactgata gcttctattt ctctgtctct gacatggacc     5880

acaaccatct ggataatcag atatttacca tcatgatcac tcctgctgaa aatccacctc     5940

cagtcattgc ttttgctgac cttatcacgg ttgatgaggg agggagagca ccactctcat     6000

ttcaccattt ttttgctact gatgatgatg acaacctcca gagagatgcc atcattaaac     6060

taagtgctct gcccaaatat ggctgcattg agaacacagg aacaggtgat cgttttggcc     6120

ctgaaactgc cagtgaccta gaggcatcat ttcctattca agacgtcctg gaaaactaca     6180

tttactactt tcagagtgtt catgaaagca ttgagccaac ccatgatatt tttagttttt     6240

atgtgagtga tggaaccagt cgttcagaaa ttcacagcat caatatcacc attgaggtaa     6300

agactttgga agttggaaag gttgagccct tgaccacaat atttcacacc attagagagc     6360

tttctttata gggactcaaa agcaaagaag attggatttg accttcaaaa ttgaaggtcg     6420

ttcttaaaat atagccttca ggaatcttgt agaattaagg ttggcatttg gggaaggctt     6480

gagttagaaa tctaaatttc catttcagga ttgaatttat ttgttcggtg tgaaaaacag     6540

tttgtgaagg tcagagatgc tttgccagtc tcatatataa atgaaaactt acatatgtct     6600

atgtttctct gaaattgtgt ttggttctat atgcatattt gccttttctt attttactgc     6660

atttatttat ttaattgtaa catcaaagaa atgtgttcct tgatgctgta tttattctca     6720

tttgagcaac tacacaggct tgctctaccg agagagagac acaggggagg ggaaagataa     6780

atctcagaat gaaataccct ctgccttggg aaaataaaat gtaaagaacc ctctgcactc     6840

ttaagggtca gtggtggaaa ggggctggca ccagggcagg gagacagctt tagagaccca     6900

cactttcaaa tatagtgtcc ttctacaggt actgtggtat gcttagcatt ttctaagaga     6960

gttctgagtt atattagtat ggtcttttat cttcaaagta tgttaatact tgtacttgtc     7020

aaagcacata tccatatttt tggtctagaa aatatggtca ttgtacttac ggaagatatc     7080

tgagaaaact tttatgaaat gtccatcagc ttcttttgaa gggggcattt tgttgcctgg     7140

acttgctctc ttttcaaact aactattttg cttgggaagt aaagatggtg ccacattaaa     7200

tgctattttg aggtgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                     7245


<210>  1990
<211>  15643
<212>  DNA
<213>  homo sapiens

<400>  1990
aactttaaaa agctgcttcg gacaaaccag agccaggatt tccactgtcg gggacccggg       60

atcggaaggg tctagcccga gggaaatgct ggaagatccc atcggccagt gaccagcaac      120

tttccggcga gattttgacg cggagaactg tgctctgcct cctcttattc tcccaaagct      180

cacgttggcg tcctgccttg cgggggaact cggcgcgctc tctgcctgag cagcgagtga      240

attgaacccc agcccgctcc ggcgcctccg ggctgatgag tgtcgctctc cgcccgtcca      300

tctctttttc ccggaggtaa aggcccgcgg tcccccacct tcagtgcgcc cgggttccaa      360

gcgccggagc cagcgttttg gcggagccgc ttcttggatg ctgaaggctg ggctcctcca      420

tcgtgggtgc cgaggcggcg atgggtgtcc tcaaagtgtg gctcgggctg gccctagcgt      480

tggcggaatt tgcagtattg cctcatcatt ccgaaggtgc ttgtgtctat caggattcct      540

tgttggcgga tgccacaatt tggaagcccg attcatgcca gagctgccgt tgccatggtg      600

atattgttat ctgcaaacct gctgtttgca gaaaccctca atgtgccttt gagaagggag      660

aagtgcttca aatagctgcc aaccaatgct gtcctgagtg tgttttgagg actccaggat      720

cttgccatca tgaaaagaaa atccatgagc atgggacaga atgggcctct tctccatgta      780

gtgtgtgctc ttgcaatcat ggggaagtcc gatgtacccc ccaaccatgc ccaccgctgt      840

catgtggaca ccaggagctg gcattcatcc ctgaaggaag ctgctgccca gtttgtgtgg      900

gccttgggaa accctgttcc tatgaaggcc atgtgtttca ggatggggag gactggcggc      960

tgagccggtg tgccaaatgt ctgtgtagaa atggggttgc ccagtgcttc acagctcagt     1020

gtcagcctct attttgtaac caggatgaga ctgtagtccg agtccctgga aaatgttgcc     1080

cgcagtgctc tgcaagatcc tgctctgcag ctggccaagt atacgagcat ggtgagcagt     1140

ggagcgaaaa tgcctgcacc acgtgtatat gtgaccgggg tgaggtcagg tgtcacaagc     1200

aggcctgcct gcccctgaga tgcggaaagg gtcagagcag ggctcggcgt catgggcaat     1260

gctgtgagga atgtgtgtct cctgccggga gctgctccta tgatggagtt gtgcggtacc     1320

aggacgaaat gtggaagggc tcggcctgtg agttctgcat gtgtgatcat ggccaagtga     1380

cctgccagac tggagagtgt gccaaagtgg agtgtgcccg ggatgaagaa ttaattcact     1440

tagatggaaa gtgttgtcct gaatgcattt caaggaatgg ttattgtgtt tatgaagaaa     1500

ctggagaatt tatgtcatca aatgctagtg aagttaaacg tattccagag ggagagaagt     1560

gggaagatgg cccttgcaag gtgtgtgagt gccgaggggc tcaggtaact tgctacgagc     1620

cctcttgccc accatgtcca gtgggcacac tggccttaga ggtgaaggga cagtgctgtc     1680

cagactgcac atcagttcat tgccatccag attgtttgac atgctctcag tctccagacc     1740

actgtgacct ctgccaagat cctaccaagt tactgcagaa tggatggtgt gtgcacagct     1800

gtggactggg tttttaccaa gctggcagtc tctgtttagc ctgccagccc cagtgctcca     1860

cgtgtaccag tgggctggag tgctcatcct gccagcctcc cctgctgatg cggcacgggc     1920

agtgtgtgcc tacctgtggg gacggcttct accaagatcg ccattcctgt gcagtctgcc     1980

atgagtcctg tgcaggttgc tggggcccaa cggagaagca ctgcttggcc tgcagagatc     2040

ccctccacgt gctgagagat ggcggctgtg agagcagctg tggaaaaggc ttctacaaca     2100

ggcagggcac ctgtagcgct tgtgaccaat cctgtgacag ttgtggcccc agtagcccca     2160

ggtgtcttac ctgtactgag aagacagtgc tgcatgatgg gaaatgcatg tctgaatgcc     2220

ctggcgggta ctatgctgat gccactggca ggtgcaaagt ttgtcataac tcatgtgcca     2280

gctgctctgg gcccacaccc tctcactgta cagcctgcag cccccccaag gctctgcgtc     2340

aaggccactg tctgccccgc tgtggagagg gtttctactc tgaccatgga gtctgcaaag     2400

cctgtcactc ctcctgcctg gcttgtatgg gtcccgcacc ctctcactgt actgggtgta     2460

agaagccaga ggaaggactg caagtggagc agctgtctga cgtgggcatc ccctctggcg     2520

agtgtctagc ccagtgtaga gcccattttt acttggagag cactggcata tgtgaagctt     2580

gccaccagtc ctgtttcaga tgtgcaggga aaagcccaca taactgcaca gactgtgggc     2640

cttcccatgt gctgttggat gggcagtgcc tctcccagtg cccagatggc tactttcacc     2700

aggaaggtag ttgcacagag tgtcacccaa cctgcaggca gtgtcatggg ccgttggagt     2760

ctgactgcat ctcctgttac cctcacatct ctcttaccaa tggtaactgc aggaccagct     2820

gcagggaaga gcagttcctc aacctcgtgg gatactgtgc tgactgccat cacctgtgcc     2880

agcactgtgc agctgatctc cacaacactg ggagcatctg cctcaggtgc cagaatgccc     2940

actacctgct gctcggggac cactgtgttc ctgactgccc ttcaggatac tatgcagaga     3000

gaggagcttg taaaaaatgc cactcctcct gcagaacctg ccagggcaga ggacctttct     3060

cctgctcctc atgtgacacc aacctcgtgc tgtcccacac tggcacctgc agcaccacct     3120

gcttccctgg gcactatctt gatgacaatc atgtttgcca gccatgcaac acacactgtg     3180

gaagctgtga ttcacaggcc agctgtacct cctgccgaga tccaaacaag gttctgctct     3240

ttggggaatg tcaatacgag agctgcgccc cacagtacta tcttgacttc tccaccaaca     3300

cgtgcaaaga gtgtgattgg agctgcagtg catgcagtgg gcccctgaaa acagactgcc     3360

tgcagtgcat ggatggctat gttctccagg atggggcctg cgtggagcag tgcttgtcat     3420

cattttacca ggactcgggc ctctgcaaga actgtgacag ctactgtctc cagtgccaag     3480

gtccccatga gtgtacccgc tgcaaagggc catttctcct cttggaagcc cagtgtgtcc     3540

aggaatgtgg gaaggggtac tttgcagatc atgcaaagca caaatgcaca gcctgccctc     3600

aggggtgctt gcagtgcagc cacagggacc gttgtcacct ctgtgaccat gggttctttc     3660

tgaagagtgg cctctgtgtt tacaactgtg ttcctggctt ttctgtccac acctctaatg     3720

aaacatgttc tggcaaaata cacaccccta gtcttcatgt gaatggttcc ctgatcctcc     3780

caattggttc aataaagcca ctggattttt ccctcctgaa tgtccaagac caggagggta     3840

gggtcgaaga tctcctattt catgttgtga gcactcccac caatggtcag ctagtgctct     3900

caagaaatgg aaaagaggtt cagctggaca aggctggccg ttttagctgg aaagatgtga     3960

acgagaagaa agtgcgtttt gtgcacagca aagaaaaact caggaaaggt taccttttcc     4020

tgaaaattag tgaccagcag ttcttctctg agccacagct gatcaacata caagcatttt     4080

caacacaggc cccctatgtg ctgagaaatg aagttctcca cattagcaga ggagagaggg     4140

caaccatcac cacccagatg cttgacatcc gagatgatga caacccacag gatgtggtca     4200

ttgaaataat cgatcctcca cttcatggcc aattgcttca gacacttcag tccccggcaa     4260

cccctatcta tcaattccag ctggatgaac tctctagagg ccttctccac tatgctcatg     4320

atggttcaga cagcacatcc gatgttgcag tcttgcaggc caatgatgga cactccttcc     4380

ataatatact gttccaagtg aagaccgtgc ctcagaatga caggggtctt cagcttgtgg     4440

ctaattcgat ggtgtgggtt ccagaagggg ggatgctgca gatcaccaac agaatcttac     4500

aggccgaggc tcctggtgcc agtgctgaag aaatcatcta caagattaca caagactacc     4560

cccagtttgg ggaggtggtc cttctagtga atatgcctgc agacagccct gcagatgaag     4620

ggcagcacct gcctgatggg aggacagcta cccccaccag caccttcacc cagcaggaca     4680

tcaatgaagg catcgtatgg tacaggcact caggagcccc agcccagagc gactccttcc     4740

gcttcgaggt gtccagtgcc tccaatgccc agacccgcct ggagagccac atgttcaaca     4800

tcgcgatctt accacagaca cctgaagcac ctaaagtgtc tctggaagca tctctccata     4860

tgactgctag agaagatggc ctgactgtta ttcagcctca ttccctctcc ttcataaact     4920

ctgagaagcc aagtggaaag attgtctaca acatcactct acctctgcat ccaaatcaag     4980

gtatcatcga gcaccgggac caccctcact ctcctatccg gtatttcacg caagaggata     5040

ttaaccaggg caaagtcatg taccgccctc ccccggcagc accccacctc caggagctca     5100

tggccttctc gttcgctggt ctcccagaat cagtgaaatt ccacttcaca gtttcagatg     5160

gagaacacac aagtccggag atggtcctca ccattcactt acttcccagt gatcagcaac     5220

tgccagtgtt ccaggtcaca gctccacggc tggcggtcag cccaggaggc agcacttctg     5280

taggacttca ggtggtagta agagatgctg agacagcgcc caaagaactc ttctttgagc     5340

ttcggagacc tccacagcat ggtgtgcttc ttaagcatac agctgagttc cgaaggccga     5400

tggccacagg tgacactttc acctatgagg atgttgagaa aaatgctcta cagtatatac     5460

atgatggttc ctctacccgg gaagacagca tggagatctc agtcacagat ggcctcacag     5520

tgacaatgct ggaggtgaga gtagaggtgt ccctgtcaga agaccgaggg cctcgactgg     5580

ctgctggctc ctctctgagc attactgttg ccagtaaaag cacagccata atcactaggt     5640

cacaccttgc ttacgtggat gattcttccc ccgacccaga gatctggatt cagttaaatt     5700

atctgccctc atatggtact ctcttaagaa tctcaggatc tgaggtggaa gagctctcag     5760

aagtttccaa tttcacaatg gaagacatca ataacaagaa aatcagatac tcagctgtgt     5820

ttgaaactga tggtcatctg gttactgata gcttctattt ctctgtctct gacatggacc     5880

acaaccatct ggataatcag atatttacca tcatgatcac tcctgctgaa aatccacctc     5940

cagtcattgc ttttgctgac cttatcacgg ttgatgaggg agggagagca ccactctcat     6000

ttcaccattt ttttgctact gatgatgatg acaacctcca gagagatgcc atcattaaac     6060

taagtgctct gcccaaatat ggctgcattg agaacacagg aacaggtgat cgttttggcc     6120

ctgaaactgc cagtgaccta gaggcatcat ttcctattca agacgtcctg gaaaactaca     6180

tttactactt tcagagtgtt catgaaagca ttgagccaac ccatgatatt tttagttttt     6240

atgtgagtga tggaaccagt cgttcagaaa ttcacagcat caatatcacc attgagagga     6300

agaacgatga gcctcccagg atgaccttgc agcccctcag agtgcagctg agctcgggag     6360

tggtgataag caattcttct ttgagcctgc aagacctgga caccccagat aatgagctca     6420

tttttgtatt gacaaaaaag cctgaccacg gtcatgtact ctggaggcaa actgcttctg     6480

agcctctgga gaatgggaga gttttagtcc agggctcaac cttcacctac caggatatcc     6540

tagctgggct ggttgggtat gtgcctagtg tccctggcat ggtcgtggat gagttccagt     6600

tctccctcac tgatggcctc cacgtggaca cagggaggat gaagatctac acagaactgc     6660

ctgcaagtga cacacctcac ttggctataa accaaggcct acagctctca gcagggtctg     6720

tagcacgcat cacagaacag cacttgaaag tgacagatat tgactcagat gaccatcagg     6780

ttatgtacat catgaaggaa gatcctggtg cagggcgcct gcagatgatg aagcatggca     6840

acctggagca aatttctatt aaaggcccca tccgaagttt cacccaggca gacattagcc     6900

aaggccacgt agaatatagt catggaacag gagaacctgg agggagcttt gcttttaaat     6960

ttgatgtggt tgatggagaa ggcaacagat tgattgacaa gtcattttcc atcagcattc     7020

tagaagacaa atccccacca gtcatcacca ccaataaagg actggtcttg gatgaaaact     7080

cagtgaagaa aatcaccacc ctgcagctgt ctgccactga ccaggacagt gggcctacag     7140

aattgatcta cagaatcacc agacagcccc agctgggcca cttggaacat gcagcatcac     7200

caggtatcca gattagttcc tttactcaag ctgatctgac ttcacgaaat gttcagtatg     7260

tccattctag tgaggctgag aaacattcag atgccttcag ctttacactg tctgatggag     7320

tcagtgaggt gactcagact ttccatatca ctcttcaccc tgtcgatgat tcgctgcccg     7380

tcgtacagaa cttaggaatg cgggtgcagg agggcatgag gaagaccatc acagagtttg     7440

agcttaaggc ggtggatgct gacacagagg ccgagtctgt cacattcacc atcgtgcagc     7500

ctccacgcca tggcaccatc gagcgaacca gcaatgggca gcatttccac ctcacctcca     7560

ccttcaccat gaaagatatc taccagaacc gggtcagcta cagccatgac ggcagtaact     7620

ccctcaagga ccggttcacc ttcactgttt ctgatgggac aaaccccttc tttatcattg     7680

aggaaggggg aaaagagatt atgacagcag cacctcagcc gttccgagta gacatcctcc     7740

cggtagatga tggcacgcct agaattgtca ccaacctggg actccagtgg ctggaataca     7800

tggatggcaa ggcaaccaac ctgatcacca agaaggaact gctgaccatg gacccagaca     7860

ccgaggacgc gcagcttgtc tatgagataa cgacgggccc taagcatggc tttgtggaga     7920

acaagctgca gcctggcaga gctgctgcca ctttcaccca ggaggatgtg aacttggggt     7980

tgattcgtta tgtgttgcac aaggagaaga tccgtgagat gatggatagt tttcagtttc     8040

tggtgaaaga cagtaaaccc aatgtggtca gcgacaatgt cttccatatc cagtggtcac     8100

tcatcagctt taaatatacc agctacaatg tcagtgagaa ggcagggtct gtcagtgtca     8160

cggtgcagag gactgggaac ctgaaccaat atgccatcgt cctgtgtcgc accgagcaag     8220

gcaccgccag ctccagctcc agggtcagct cccaacctgg gcaacaggac tatgtagagt     8280

atgctggcca ggtccagttt gatgagcgag aggacaccaa gtcctgcacc attgtcatca     8340

acgatgatga cgtgtttgaa aatgttgaga gtttcactgt ggagctcagc atgccagctt     8400

atgccctgtt aggggaattc acccaggcga aggtcattat caacgatacc gaggatgaac     8460

ccacattaga gtttgacaag aagatctact gggttaacga gagcgctggt tttctgtttg     8520

cacctattga aagaaaagga gatgcaagca gcattgtatc tgcaatttgc tacacagtcc     8580

ctaagtcagc tatgggaagt agcctctatg ctctagaatc aggctctgat tttaaatcta     8640

gagggatgtc tgccgcgagt cgtgtgatat tcgggcctgg tgtgaccatg tccacctgtg     8700

atgtcatgct tattgatgac agcgagtatg aagaggaaga agagtttgag attgccttgg     8760

cagatgcctc tgacaatgcc cgcattggaa gggtggcgac agccaaggtg ctcattagtg     8820

gtcccaacga tgcctcgact gtgtccctgg gcaacacggc tttcactgtc agtgaggacg     8880

caggcacagt aaagattcca gttatccgcc atggtactga cctctctact ttcgcatctg     8940

tctggtgtgc aacgcggccc tcagacccag cttctgccac accaggagtt gactacgttc     9000

ccagctctcg gaaggtggaa tttgggcctg gtgtcattga acagtattgc accttgacta     9060

tcttggatga cactcagtat ccggtaattg aaggactgga gacatttgtg gttttcctca     9120

gctcagcaca aggagccgaa ctgaccaaac ccttccaggc agtcattgca attaatgaca     9180

cattccaaga tgtgcccagc atgcagtttg ccaaggattt gctcctagtg aaggagaagg     9240

agggtgtcct gcatgtccct atcactcgga gcggagacct gagctatgag tcatcagtga     9300

ggtgctatac tcagagccat tccgctcagg tcatggagga ctttgaggag agacaaaatg     9360

cagactcttc acggattaca tttctcaaag gggacaaagt gaagaactgt acggtctata     9420

tccacgatga ctccatgttt gagccagagg aacagttcag ggtctacctc ggccttcctc     9480

ttggaaacca ctggagtgga gctagaattg gaaagaataa catggccacc atcaccatat     9540

ccaatgatga agatgccccc accattgagt ttgaagaagc tgcataccaa gtccgggaac     9600

ccgcaggccc agatgccatt gcgattctga acatcaaggt gatccgcaga ggggatcaga     9660

acaggacctc caaggttcgc tgcagcacgc gggatggctc tgcccagtct ggtgtggatt     9720

attacccaaa gagccgagtc ttgaagttca gtcccggtgt ggatcatatc ttttttaaag     9780

ttgagatcct gtccaatgaa gaccgggaat ggcatgaatc tttctcacta gtccttggcc     9840

cagatgaccc agtggaagca gttcttgggg atgtgactac tgccacggtg acaattctag     9900

accaggaggc agcagggagc ctcatattgc cagcaccacc cattgtggtc acacttgctg     9960

actatgacca tgtggaagaa gttaccaagg aaggagtcaa gaaatccccc tccccaggct    10020

acccactggt ctgtgtcacc ccctgcgacc ctcatttccc cagatacgct gtcatgaagg    10080

agcgctgcag tgaggccggc atcaaccaga catctgtgca gttcagctgg gaagtggctg    10140

cccccactga tggcaatggg gcccggtctc cctttgaaac catcactgac aacacaccat    10200

tcaccagtgt caaccacatg gtcctggaca gcatttactt cagccggagg ttccatgtgc    10260

gttgtgtggc caaggctgtg gacaaggtgg gccatgtggg gaccccctta aggagcaaca    10320

ttgttaccat tggaacagac agtgctatct gccacacacc agtggtggct gggacatcca    10380

gaggcttcca ggctcagtcc ttcatcgcaa ccttgaaata cctggatgtc aaacataagg    10440

agcatccgaa cagaatccac atttcggtgc agatcccaca ccaggatgga atgctgcccc    10500

ttatctccac catgccgttg cacaacttac attttctact gtctgagtcc atctacagac    10560

accagcacgt ctgctccaat ttagttacca cctatgacct gagaggcatc tcagaggcag    10620

ggttcctgga tgatgtggtc tatgatagca ctgccctggg gcctggctac gatcgcccct    10680

tccagtttga ccccagcgtg cgagagccga agaccatcca gctctacaaa cacctgaacc    10740

tgaagagctg cgtgtggacc tttgatgctt attatgacat gactgagctg attgacgtct    10800

gtgggggctc tgtaaccgct gacttccagg tgagggactc tgcccagtcc ttcttgacag    10860

tgcacgtgcc tctatatgtg tcctacatct atgtgacagc ccccaggggc tgggcctcct    10920

tggagcacca caccgagatg gagttttctt tcttctatga cactgttctc tggagaacag    10980

gaatccagac agacagcgtg ctctctgcaa ggcttcagat aataagaatc tacattcgag    11040

aggatggccg tcttgtcatt gaattcaaga cccatgccaa attcagagga cagtttgtga    11100

tggagcatca cactctccca gaagtgaaat ctttcgtatt gactccagac cacctaggag    11160

gaattgaatt tgacttgcag ctattatgga gcgctcagac ttttgattct ccacatcaac    11220

tctggagagc cacaagctct tataacagga aggactactc aggagagtac accatctacc    11280

tgatcccttg cacagtgcag cccacacagc catgggttga cccaggagag aagcctttgg    11340

cctgcactgc acatgcccca gaaagattcc tgatacccat tgcattccag cagaccaacc    11400

gccctgtgcc agttgtgtat tcacttaaca ctgaatttca gctctgcaat aatgagaagg    11460

tgttcctaat ggatcccaat acatctgata tgtcactagc agaaatggat tacaaaggag    11520

ccttttcaaa aggtcaaatc ctttatggcc gagtactttg gaatccagaa caaaatctta    11580

attctgctta caaactccag ctggagaaag tctatctttg tacgggcaag gatggttatg    11640

tgcctttctt tgatcccacg gggacaatct acaatgaagg gccccagtat ggatgcattc    11700

agccaaacaa acacctaaaa cacagattcc tgctgttgga ccgcaatcag ccagaggtaa    11760

ctgataagta cttccatgat gtgccttttg aggctcactt tgcctctgag ttgcctgatt    11820

tccatgtggt cagtaacatg ccaggtgtgg atggatttac tctaaaagta gatgcactct    11880

ataaggtgga agcaggacac cagtggtatc tccaggtcat ctacatcatt ggccctgaca    11940

ccatctcagg gccccgggtc cagcgctctc tcacagctcc actcagacgc aaccgaaggg    12000

acctggtaga gcccgatggc cagctgatcc ttgatgattc cctcatctat gacaatgaag    12060

gagaccaagt caagaatggc accaatatga agtccctgaa tctggagatg caagagttgg    12120

cggtagctgc gtccctgtca cagactgggg cgtccattgg cagtgccctg gctgcaatca    12180

tgcttctact tctggtgttt ttggtggctt gttttatcaa caggaaatgc cagaaacaga    12240

ggaagaagaa gcccgcagag gacattttgg aagaatatcc tctgaatacc aaggtagaag    12300

tgcccaagag gcacccggac cgggtggaga agaacgtgaa tagacactac tgcactgtgc    12360

ggaacgtcaa catcctgagt gagcctgagg cggcttacac gttcaaaggt gctaaagtca    12420

aaagactgaa tctagaagtc agagttcaca acaatttaca agatggaaca gaagtttaat    12480

ggaggagacc tatgtgtatt tttttctaaa atcattttta taaaatgggg ggaaatactg    12540

gtatttttat aatctcgcag ataaaaaagg gaaaactata gctttgagtg gcagacagca    12600

cacatcacat gcatcaactc acaactgagc tacctcattc agcaaagaac cactgagaac    12660

cccagagtat tacagttatt tccgtagatc cctttaatag tgtcaacaac tgtacacagc    12720

tccttctgta aggctggtct tagaaaacaa gtactttagt atcaggacag gagttgaaca    12780

attaggttag cagatggaga tgagaggact gggtagagta ccatggcaga tctcagagag    12840

aagaagtagg tacgggcctt tggttccctc ccccagcccc agctttctcc tacagggctt    12900

ttcctgagtc cccagacagc agagtatgaa ctgctgacac ccagattcca ttaaaaattc    12960

tgctaatcga cacaacacat atatttgctc atgatttcac ttgacagcgt atgctccttg    13020

gcctctaatt gtactttgct tttccagagc cctttttacc tggggatttc agtgtgctta    13080

agtaaaatcc tctgaaaacc acgggagcct ctgcctcctc agccacagag aactccctcc    13140

tacaaagggg gagactgaaa cccgagttaa ggaggggcct ggcaggcgta tcagagcaca    13200

ttagtgatgc ccttcacccc agggaggtgt ctgttcccaa ctagtttatg tggcactgag    13260

acatccatcc ctgaccaagg atgctgcgaa acaggatcaa tgtactacgg ccttttaatt    13320

caacattgcc ataaatgctt taaagaaaac ccaccacact ttcctcctac tccggtcttt    13380

gcccgttcct gtaacagaca atcccatgtc ctaggtatgg ttttttattc tgttagtgct    13440

tcgggaaagt aagtgattca tttgaataag gcaaattagg agaaagccca ggttggggtg    13500

aaatcagact taacagatac atgctggttc tccttgctgt gtgtgacaca gcagacagag    13560

gcactattcc tggtgcagta tttcagggat ttctctttga ggggttcttt tctggtagct    13620

caggcaatta tttttaccat atcagcacat gacaaggcca tgaacacatg gctctaaaat    13680

aatttagtgt tcaagtatca gcttaactat tttgtgtagg ctacacacag cttgcttttg    13740

tttctcttct gtttctgcct tattggcgga aacataagcg tgcatgccat gttgttttga    13800

attggaggca caatttcatt attcgagagt aaaagacatg tcctcttctg atgcatggca    13860

caccatagtc accaagcaaa taacagagcc ttcacattgt gtaatatttg tatgagaatg    13920

actcaagctc tttgagaaca ttccaaacta gtaacatttc gctactaaaa gctagaaagg    13980

atgaactgtg aaaggttcta ggcagctctg tgagactcca agctccttga aagtaggacc    14040

tttgtgagcc acgcctttca ttcttcaaca gtgccttgca tgtaacaagc actccagaaa    14100

tgtttgttga atgaatgaat ggtgtcatgg gtgaatgatg gggagtaaat ttaggaaggg    14160

gaagtgagag agtatggtgg caatatcaca agggaggaga gaggaaaaca attatcttct    14220

ctacttggat tatgagataa ccttttcttg gaggaaagaa acaccgcttt acaaaggcat    14280

gactctggcg gtggtcctaa ggaagcatga gcagaaaatt cataaaaatg tatcatcagc    14340

aggagatgag actatgaatt ggcatccaga acaggagatt tagagcaaaa tctaatttag    14400

cattctgaga tgagtgtcag gttttcagga gagaatgagt tggggtgagc ccagagtctg    14460

aaactcctga ctggtcaggt gctacttaag accagcttgg gcaattcagg gcagaactcc    14520

tgtatcagcc tcatggacac ccagaattgg tatctcatgg ctggagagct gatcagccag    14580

gcacagaatc tccagaacaa cctagagagt gaatgctaat ttgtagagcg aacttccatt    14640

tggcccatta tttgtaactg tgtaactgct ccaagtgcca gaatgcttac acgttaaagc    14700

agcacctttc catttgccca catattcttc ttgcacaccc cttccattac tgctgaatag    14760

gacattgcat gggaagagta cagaggtggc agaatgaagc tagagtggga aggactaaag    14820

actgagcccc agagtgctcc cagcaaccgc cacgtacaag gtctgaaatg acaagggcaa    14880

gagtgagata ggaaactgtg tgtgaaagga aagcccttgc agtatttctg cctccctttc    14940

tttctgcctt tcaccccact aaatgtatgt tattgaatgc cagtacttct ctagtggatg    15000

cacacttgtt aaatagtgtt aagagatgtg gagatgagat ataccccttt gatgtagaat    15060

tattcatttg gtttgtttca tacttcatta taggaatcaa gtaatttgat gactaatgtg    15120

gattatattt cagtcaaagc tctgctttca atttctctga tttgctcact aatgccttgt    15180

gtgtgtttta ctaacctttt atatcttgcc ttcaagtgag aaggaacaaa caactctcag    15240

tggttactac ttgcttttat atgctggctg tgaaggttaa aagaaagaat ggtctgtacc    15300

attctgcttt gctgcccttt tattgtaccc caggcctcct agaggactcc tgcagattct    15360

attgttgggt gggaaatagt gttggaatgt gtttgcacag tcttatgata ttcagtctca    15420

gtctgctata ggtatttgtt attcttggat actacacacc tgctcagact gagtaaacat    15480

ttgtggtgct gtcaacctga tttcttgact ctcaaatgat ttttgtattt ccaatatgaa    15540

tttgtgtgtt atgaatttct gatttctcca atagtatatg ccactatata aatttgtatt    15600

aataaatgac agtcttgttg gtttaaaaaa aaaaaaaaaa aaa                      15643


<210>  1991
<211>  4842
<212>  DNA
<213>  homo sapiens

<400>  1991
ggggcggggc ggacgcggag cgcccctctg gctggcgggg ccaaggggct gagaggagtg       60

gggcaggctc ggcgccggta ggaagagtca gaggggtgac cagagagccc aacgcctggt      120

gctcaagact ttctccgagc tatgaaaccc acgtagtcga acaccgtgat gcttctcctg      180

cagggcgtgt gatgaggagg cgagcttggc tttggagtgc tgggaacctg aggaattgcc      240

aaggacccag agcccagccc tgaccaccag agtgcccaaa acacaatgaa caaattgaat      300

tttcataaca acagagtcat gcaagaccgc cgcagtgtgt gcattttcct tcccaacgat      360

gaatctctga acatcatcat aaatgttaag attctgtgtc accagttgct ggtccaggtt      420

tgtgacctgc tcaggctaaa ggactgccac ctctttggac tcagtgttat acaaaataat      480

gaacatgtgt atatggagtt gtcacaaaag ctttacaaat attgtccaaa agaatggaag      540

aaagaggcca gcaagggtat cgaccaattt gggcctccta tgatcatcca cttccgtgtg      600

cagtactatg tggaaaatgg cagattgatc agtgacagag cagcaagata ctattattac      660

tggcacctga gaaaacaagt tcttcattct cagtgtgtgc tccgagagga ggcctacttc      720

ctgctggcag cctttgccct gcaggctgat cttgggaact tcaaaaggaa taagcactat      780

ggaaaatact tcgagccaga ggcttacttc ccatcttggg ttgtttccaa gagggggaag      840

gactacatcc tgaagcacat tccaaacatg cacaaagatc agtttgcact aacagcttcc      900

gaagctcatc ttaaatatat caaagaggct gtccgactgg atgacgtcgc tgttcattac      960

tacagattgt ataaggataa aagggaaatt gaagcatcgc tgactcttgg attgaccatg     1020

aggggaatac agatttttca gaatttagat gaagagaaac aattacttta tgatttcccc     1080

tggacaaatg ttggaaaatt ggtgtttgtg ggtaagaaat ttgagatttt gccagatggc     1140

ttgccttctg cccggaagct catatactac acggggtgcc ccatgcgctc cagacacctc     1200

ctgcaacttc tgagcaacag ccaccgcctc tatatgaatc tgcagcctgt cctgcgccat     1260

atccggaagc tggaggaaaa cgaagagaag aagcagtacc gggaatctta catcagtgac     1320

aacctggacc tcgacatgga ccagctggaa aaacggtcgc gggccagcgg gagcagtgcg     1380

ggcagcatga aacacaagcg cctgtcccgt cattccaccg ccagccacag cagttcccac     1440

acctcgggca ttgaggcaga caccaagccc cgggacacgg ggccagaaga cagctactcc     1500

agcagtgcca tccaccgcaa gctgaaaacc tgcagctcaa tgaccagtca tggcagctcc     1560

cacacctcag gggtggagag tggcggcaaa gaccggctgg aagaggactt acaggacgat     1620

gaaatagaga tgttggttga tgacccccgg gatctggagc agatgaatga agagtctctg     1680

gaagtcagcc cagacatgtg catctacatc acagaggaca tgctcatgtc gcggaagctg     1740

aatggacact ctgggttgat tgtgaaagaa attgggtctt ccacctcgag ctcttcagaa     1800

acagttgtta agcttcgtgg ccagagtact gattctcttc cacagactat atgtcggaaa     1860

ccaaagacct ccactgatcg acacagcttg agcctcgatg acatcagact ttaccagaaa     1920

gacttcctgc gcattgcagg tctgtgtcag gacactgctc agagttacac ctttggatgt     1980

ggccatgaac tggatgagga aggcctctat tgcaacagtt gcttggccca gcagtgcatc     2040

aacatccaag atgcttttcc agtcaaaaga accagcaaat acttttctct ggatctcact     2100

catgatgaag ttccagagtt tgttgtgtaa agtccgtctg tgtgcagctg tacaggcagc     2160

ttactgtttg ctagaggatg cgaaagtcat aagttcttta catattactt gtgccatatc     2220

ttcttcaccc taaacatagc tctttcttta taatatttgt gatgatggaa acaaaagcct     2280

tggaacaatt gcactttaag tattacacag aagtaaaaga actacagaaa atgtacagca     2340

agacaagtgc ccggaagttc actgatcctt cagaaggaaa tgcgctttac tgattgcaaa     2400

gccttcagaa tattggagtg tggtgtgttt gctcatctga tgctttttag ttcagttaca     2460

tgtaacatca cattttttta tcacgtgaaa gatgttagat ttgtttgctt ataaattttt     2520

taccactccc acataaaatg ctcatagttt gggagaggaa agagggaaga ttctctcttc     2580

ttttaacaga gagatgattg ctctgtatac ccattgcttc ctccctgagg ctgtcccaaa     2640

gtgaacactg atggagtggt caaaatcata aggttgtagc aagccaaaga tacgtatgtg     2700

acagaagcac ataagcaata agcagaaaac cagaagtgca tgctgtgatg cctgtgactc     2760

cttcatcccg ctcagtgcca tgtcctcttt tgtgatcttc cagaaagctc caggattcat     2820

ttgagttcca catccaagta acagatgaat tatattcatg ttgtaatgca ttttgtggag     2880

tttacaaaac cagtgtctgt taaaactttg gaaaatgtct tagaaaacgt tggtgcttgg     2940

tgatgcttta tttgtttaat tatcaagaac aaattatggc aatgctagtt tctgcttaac     3000

caaaatactc tgtgtatata ttatacatat ataaatacat gggattgtgt atgtctatat     3060

gtgtttaaag cttactatgt cttcattttg gcttccatga ctatctttta tacatggaat     3120

tccttaagat tgagaatatg tcactgagtg aatgatacct gcagacagtc agttgatata     3180

tgtagagttc agaatgactg ttttctcatg tgcctttggc catgattctc aacactgatt     3240

gtataacaga attttggggg gagcttttaa aaaataatga ctgagtctcc caccagaccg     3300

attacatcat tctcttgtgg cgggacccaa gtagaattgc cttttctttt aaagttctcc     3360

agatggagct aatatgcaac aaagttgaaa accactgatc ctgggggtgt cttgttaatt     3420

ttgaagtaaa agtgtacaga agacgtagtg tatgagaaag ggccattttt aagacagtta     3480

cctgttgtgc tgctgttaca atatataatg aaaccaagtc aggggagtga atttatcaat     3540

cttttgatgt aaagtaaaaa cgtagttcac acttcaggag agaacttcat agcacaatgt     3600

ctttctataa gatattttta atgatttagt attttacaac atttgtttac catattttga     3660

tataccattt ttttctatct gcccagtttt attaaaaaaa ctatatatta ttttctaaag     3720

aaacaatcat atttttatac aaaattatgt tttcaggtaa cgaaatagat gtagggtaca     3780

gtggaacata agcagtgtta cccctggctg ggagtcagta ttatacaaca aatggtgagc     3840

tggaacatgc cctgtctgtg ctgtccctcc tgtgctgggt cgcggatgtg taggcaacat     3900

tgccttatca cgctaggttc acctgacact ttaaaaggaa aaaaagttcc atagagttct     3960

gtggtcacaa aattgttttg cttttatcaa atactttaat agaaccaaag ttgcagatat     4020

tggaatgtat ggaagtatct cagtctctgc ataagaggat taaagtatga aaggatcatt     4080

taatgactgt tttacttata agtcattaag taatccacca tttcttatgg atgatgctta     4140

agcctggtga ggtttgtact ctaaggagcc cagatcataa tgcagtgcat ttccttagcc     4200

cttagagttt cttgcaaaca tttaaaaaaa gacatattta agaaagaaag ataaagaaaa     4260

aacatattta attactgtaa acaggtactg ctttatgttt attttctctc tacttcaacc     4320

aaaatcagat ctttgaggtt ttgctgacat tgttggtggt tttgcacatg ttctttctaa     4380

ttggatttat gaatagttct atgggttttc aaagatgaat catgctaaga acacttctgc     4440

tttttgatcc actgtttgca gcagaattat atatatgtat aggaaaaatc cactttgaat     4500

aatccatgtt ttgtatttgg aaattgtttt taaaaataaa aaggaaagga aatatataaa     4560

gctgttattt attctgcatt tcttacatat ctatcgcttg tcagtatacc cgttttggta     4620

tatattgcct ctgcacatct acatttgtat atgcaacagt gagctttata tctacataaa     4680

ctgtaaataa tcctttctgt gaaaggatca tcatatcaag atgataccaa aagtatgtaa     4740

aaagaaacct gcattatttt gtaattattt cttatagata tttcatggta agattagcag     4800

tcaataaagt tacttttttg cctttaaaaa aaaaaaaaaa aa                        4842


<210>  1992
<211>  5880
<212>  DNA
<213>  homo sapiens

<400>  1992
gaagtcagcg ctgagtccca gaaaaacaga gcggggccag ctgcagcgtg tagtgcgagt       60

ggggcggacg cgcgcagccc gcccgcccgg cgaccagcaa ggagttggca tcctttggaa      120

gagttcgtga aagctttctg cccagagctc ctggaccaat gcatcttccc accaccttaa      180

accactgagc agttcagagc cccagttgca gacgacttgt cctgccacca ccatgagttc      240

tgaatgtgat ggtggttcca aagctgtgat gaatggcttg gcacctggca gcaatgggca      300

agacaaagca actgccgacc ctttacgcgc acgctctatt tctgctgtta aaatcattcc      360

tgtgaagaca gtgaaaaacg cctcaggcct agttctccct acagacatgg atcctacaaa      420

aatctgcact gggaagggag cggtgactct ccgggcctcg tcttcctaca gggaaacccc      480

aagcagtagc cctgcgagcc ctcaggaaac ccggcaacac gaaagcaaac caggtctgga      540

gccagagcct tcttcagcag atgagtggag gctttcttcc agtgctgatg ccaatggaaa      600

tgcccagccc tcttcactcg ctgccaaggg ctacagaagt gtgcatccca accttccttc      660

tgacaagtcc caggattcca gtcctctact aaatgaagtt tcttcttccc ttattggaac      720

tgattcccaa gcctttccat cagttagcaa gccttcatcc gcctatccct ccacaacgat      780

tgtcaatcct actattgtgc tcttgcaaca caatcgagaa cagcaaaaac gactcagtag      840

cctttcagat cctgtctcag aaagaagagt gggagagcag gactcagcac caacccagga      900

aaaacccacc tcacctggca aggctattga aaaaagagca aaggatgaca gtaggcgggt      960

ggtgaagagc actcaggact taagcgatgt ttccatggat gaagtgggca tcccactccg     1020

gaacactgag agatcaaaag actggtacaa gactatgttt aaacagatcc acaaactgaa     1080

cagagatgat gattcagatc tgtactctcc cagatactca ttttctgaag acacaaaatc     1140

tcccctttct gtgcctcgct caaaaagtga gatgagctac attgatggtg agaaggtagt     1200

caagaggtcg gccacactac ccctcccagc ccgctcttcc tcactgaagt caagctcaga     1260

aagaaatgac tgggaacccc cagataagaa agtagacaca agaaaatatc gtgcagagcc     1320

caagagcatt tacgaatatc agcctggcaa gtcttccgtt ctgaccaacg aaaagatgag     1380

ctcagccatc agccctactc cggaaatttc ttcagagact cctggatata tatattcttc     1440

caacttccat gcagtgaaga gggaatcaga cggggctcct ggggatctca ctagcttgga     1500

gaatgagaga caaatttata aaagtgtctt ggaaggtggt gacatccctc ttcagggcct     1560

gagtgggctc aagcgaccat ccagctctgc ttccactaaa gattcagaat cgccaagaca     1620

ttttatacca gctgattact tggaatccac ggaagaattt attcgaagac gtcatgatga     1680

taaagagaaa cttttagcgg accagagacg acttaaacgc gagcaagaag aggctgatat     1740

tgcagctcga cgccacacag gcgtcattcc gacgcaccat cagtttatca ctaatgagcg     1800

ctttggggac ctcctcaata tagacgatac tgcaaaaagg aaatctgggt cagagatgag     1860

acctgccaga gccaaatttg actttaaagc tcagacacta aaggagcttc ctctgcagaa     1920

gggagatatt gtttacattt ataagcaaat tgatcagaac tggtatgaag gagaacacca     1980

cggccgggtg ggaatcttcc cacgcaccta catcgagctt cttcctcctg ctgagaaggc     2040

acagcccaaa aagttgacac cagtgcaggt tttggaatat ggagaagcta ttgctaagtt     2100

taactttaat ggtgatacac aagtagaaat gtccttcaga aagggtgaga ggatcacact     2160

gctccggcag gtagatgaga actggtacga agggaggatc ccggggacat cccgacaagg     2220

catcttcccc atcacctacg tggatgtgat caagcgacca ctggtgaaaa accctgtgga     2280

ttacatggac ctgcctttct cctcctcccc aagtcgcagt gccactgcaa gcccacagca     2340

acctcaagcc cagcagcgaa gagtcacccc cgacaggagt caaacctcac aagatttatt     2400

tagctatcaa gcattatata gctatatacc acagaatgat gatgagttgg aactccgcga     2460

tggagatatc gttgatgtca tggaaaaatg tgacgatgga tggtttgttg gtacttcaag     2520

aaggacaaag cagtttggta cttttccagg caactatgta aaacctttgt atctataaga     2580

agactgaaaa ccatggagat tatttttatt ggaggaggaa gcatcattca tgaaccgatc     2640

tttttagttg agtcagtagg aaaattaata cagtggataa agtaagaagc aaaagacagg     2700

gacagagaag tgttgtgttt aaaacccaag cctgtctaag gttactgtgt attagacagg     2760

gccgaactag tgtgctgagc aaaaagaatt gaagcaaatt gtatttactt agccgcttct     2820

gggagccact tcagcctttc ccctcccctc cacttcttgg gtaatctgac ctgaagcata     2880

gtccaggagc agagttagcc agaaatgcct cctgctgccc cagccttaga gagctcccat     2940

ctcaatcatt gagcctgaag gcttcaagcc caagaatgca acaagacccc cagcctacat     3000

ttctcagctc ccctggagcc agctgatcct gtaacgctgc tggaggtcag tctgagctac     3060

caagactgtc cctagacaaa ggtggagtcc cccacactgc ccaagaccaa atccctcact     3120

caacctgctg aggtgtggat ggggaaacag aggcaaaact gaggcacctg atgcattcag     3180

cctgctgtgc agcagtgcca ttgactgccc tgatgttcag agagaaacgc acacaaggtt     3240

tgcccatgag aattggggag cagatggcca agcagatagg ttatgtctgt tttctgagtg     3300

atgaagtcag gaagccctgt ggctctggag gccacttgtg gttcattctt ttcccatatc     3360

cttggctttt agaaatggtt accttcagga cagtgcagct gcatttatca gagcactatt     3420

gctaagtttt cttttctggc ttgtgttttt ctgggacagt ttagaattgg gaggcctatt     3480

ctcatagaac accaaaaatg atgttcagtg attcatttaa catacaccaa tgtactctgg     3540

ctgctggggg gacaaccata agcaagacat gcccagggtt tgccgtggct ccagatctac     3600

tccctgtagg agttcaagga tcacacaaac ggtagtaacc agggttgtga atctgagtac     3660

accctggcaa ggcttctctt cagactgaag cagcaattct gccactacca gcagcaacca     3720

ggacgtctgt tctttgtggg ggccagatca gaagagagag gcccctgtga cgcccgggct     3780

gcttggtcac aactctgtcc aattcaagga tgtttatcgg cctctcttag atcctgagtg     3840

agacaaatac agaaatgacc cattccctgc ccaccagaaa ctcagaggtg attggggaga     3900

ctgacacagg aaaatgaact taatcaagag agactgtgat atgtgctaag aagggtgtga     3960

gggagggaga gatgaatttt ccctggaggg atcctagaaa gcattgtcat attgccatct     4020

ccattagctc acttttaaac aactagggtg ctggaagaac ctttgtctga gggtagttca     4080

tagctggaaa tacttggaat attttccaga gtctctaaac tctcatcttc ccccacagat     4140

acacatccaa gctcacaaat aggagtagca attctaggtg gtagggttgt gtacggaacc     4200

cctggctgtc tgcatatatc tcagaattac cccaggacca ttgtcccaaa gtctagagtc     4260

tttacaggta ggcaaaattt gttttcaatg cctgtgcctc agctgctgtc acaaataccc     4320

atcttaggat cccatcagct tcccatcccc caccagacag ccacagtacc ctcactttct     4380

ccctattgtt ctttcaaatc ctgttctcag gaaagaaact gccactaatt cattcacact     4440

aaggtgtaaa tgattgataa taggaatgag ttacctcttc ccacagacat ttgtttttaa     4500

gtatgacaga gcagggcctt aatcccaagg gaaaaggtta tggaactgga gggggtgagc     4560

tttctgggta gaaggagact tcctgaattt ccttaaaacc cagtaagagt aagacctgtt     4620

gttttggaag gtctgctcca ccatctaaga gcactgtttt tttttttttg ttgttgttgt     4680

tgttttacgg tctctgaggg aatatagtaa aaatgcatat gcacgtgcaa tttgcacggc     4740

agcatttcac cgattgtgga ctgtattggc taatgtgttt cctggtcttt agatgcaaac     4800

cattaataac actatcttat ctcatagttt tttcaggggt gcttcttgat tagtagggaa     4860

ttttgaacac ctctttaaat acagctagaa aataaaacca atttgtaaag ccacatttgc     4920

atatgatgcc agcctcacgc atttgtatat ctccagaaat tcaggtatgc ctcaccaatt     4980

tgcccgtctt taataaaatc ttgtgttaaa atttgcatca cgtcgccttc ctatgtatga     5040

cgaaacaaga aacagagatt tccaattgct cttttgtctt cagacattta gtaatataaa     5100

gtacctattt ttatgctgaa atgtttatac aggtttatta atagcaagtg caactaactg     5160

gcggcatgcc ttgcaacaca ttttgatata ttagccatgc ttccgggtaa aggcaagccc     5220

caaactcctt atcttttgca gtctctctgg gatcagtaaa agaaaaaaaa aataatgtgc     5280

ttaagaagtg ggactgtaaa tatgtatatt taactttgta tagcccatgt acctaccttg     5340

tatagaaaaa taattttaaa aatttgaatg gaagggggta aaggaagtca tgaagttttt     5400

ttgcattttt atttaaatga aggaattcca aataactcac ctacagattt ttagcacaaa     5460

aatagccatt gtaaagtgtt aaaatttacg ataagtattc tattggggag gaaaggtaac     5520

tctgatctca gttacagttt ttttttcctt tttaatttca ttattttggg tttttggttt     5580

ttgcagtcct atttatctgc agtcgtatta agtcctattg ctagaatagg ttactacaaa     5640

aaaggttata ttctgaaaga aaaataactg acattatata taaccaatta atttaaagta     5700

ttgccattta aattacacac tgagagcatg tcctatgcag acatagattt ttctgttcat     5760

ttatttttct tcattgcagt ggattgattt gataaataga tgtgttgaat tactacattt     5820

gctgtacata ttatttaata aactttattc agaattgcgt ggcaaaaaaa aaaaaaaaaa     5880


<210>  1993
<211>  5402
<212>  DNA
<213>  homo sapiens

<400>  1993
agcagttcag agccccagtt gcagacgact tgtcctgcca ccaccatgag ttctgaatgt       60

gatggtggtt ccaaagctgt gatgaatggc ttggcacctg gcagcaatgg gcaagacaaa      120

gacatggatc ctacaaaaat ctgcactggg aagggagcgg tgactctccg ggcctcgtct      180

tcctacaggg aaaccccaag cagtagccct gcgagccctc aggaaacccg gcaacacgaa      240

agcaaaccag atgagtggag gctttcttcc agtgctgatg ccaatggaaa tgcccagccc      300

tcttcactcg ctgccaaggg ctacagaagt gtgcatccca accttccttc tgacaagtcc      360

caggattcca gtcctctact aaatgaagtt tcttcttccc ttattggaac tgattcccaa      420

gcctttccat cagttagcaa gccttcatcc gcctatccct ccacaacgat tgtcaatcct      480

actattgtgc tcttgcaaca caatcgagaa cagcaaaaac gactcagtag cctttcagat      540

cctgtctcag aaagaagagt gggagagcag gactcagcac caacccagga aaaacccacc      600

tcacctggca aggctattga aaaaagagca aaggatgaca gtaggcgggt ggtgaagagc      660

actcaggact taagcgatgt ttccatggat gaagtgggca tcccactccg gaacactgag      720

agatcaaaag actggtacaa gactatgttt aaacagatcc acaaactgaa cagagatgat      780

gattcagatc tgtactctcc cagatactca ttttctgaag acacaaaatc tcccctttct      840

gtgcctcgct caaaaagtga gatgagctac attgatggtg agaaggtagt caagaggtcg      900

gccacactac ccctcccagc ccgctcttcc tcactgaagt caagctcaga aagaaatgac      960

tgggaacccc cagataagaa agtagacaca agaaaatatc gtgcagagcc caagagcatt     1020

tacgaatatc agcctggcaa gtcttccgtt ctgaccaacg aaaagatgag ctcagccatc     1080

agccctactc cggaaatttc ttcagagact cctggatata tatattcttc caacttccat     1140

gcagtgaaga gggaatcaga cggggctcct ggggatctca ctagcttgga gaatgagaga     1200

caaatttata aaagtgtctt ggaaggtggt gacatccctc ttcagggcct gagtgggctc     1260

aagcgaccat ccagctctgc ttccactaaa gattcagaat cgccaagaca ttttatacca     1320

gctgattact tggaatccac ggaagaattt attcgaagac gtcatgatga taaagagatg     1380

agacctgcca gagccaaatt tgactttaaa gctcagacac taaaggagct tcctctgcag     1440

aagggagata ttgtttacat ttataagcaa attgatcaga actggtatga aggagaacac     1500

cacggccggg tgggaatctt cccacgcacc tacatcgagc ttcttcctcc tgctgagaag     1560

gcacagccca aaaagttgac accagtgcag gttttggaat atggagaagc tattgctaag     1620

tttaacttta atggtgatac acaagtagaa atgtccttca gaaagggtga gaggatcaca     1680

ctgctccggc aggtagatga gaactggtac gaagggagga tcccggggac atcccgacaa     1740

ggcatcttcc ccatcaccta cgtggatgtg atcaagcgac cactggtgaa aaaccctgtg     1800

gattacatgg acctgccttt ctcctcctcc ccaagtcgca gtgccactgc aagcccacag     1860

caacctcaag cccagcagcg aagagtcacc cccgacagga gtcaaacctc acaagattta     1920

tttagctatc aagcattata tagctatata ccacagaatg atgatgagtt ggaactccgc     1980

gatggagata tcgttgatgt catggaaaaa tgtgacgatg gatggtttgt tggtacttca     2040

agaaggacaa agcagtttgg tacttttcca ggcaactatg taaaaccttt gtatctataa     2100

gaagactgaa aaccatggag attattttta ttggaggagg aagcatcatt catgaaccga     2160

tctttttagt tgagtcagta ggaaaattaa tacagtggat aaagtaagaa gcaaaagaca     2220

gggacagaga agtgttgtgt ttaaaaccca agcctgtcta aggttactgt gtattagaca     2280

gggccgaact agtgtgctga gcaaaaagaa ttgaagcaaa ttgtatttac ttagccgctt     2340

ctgggagcca cttcagcctt tcccctcccc tccacttctt gggtaatctg acctgaagca     2400

tagtccagga gcagagttag ccagaaatgc ctcctgctgc cccagcctta gagagctccc     2460

atctcaatca ttgagcctga aggcttcaag cccaagaatg caacaagacc cccagcctac     2520

atttctcagc tcccctggag ccagctgatc ctgtaacgct gctggaggtc agtctgagct     2580

accaagactg tccctagaca aaggtggagt cccccacact gcccaagacc aaatccctca     2640

ctcaacctgc tgaggtgtgg atggggaaac agaggcaaaa ctgaggcacc tgatgcattc     2700

agcctgctgt gcagcagtgc cattgactgc cctgatgttc agagagaaac gcacacaagg     2760

tttgcccatg agaattgggg agcagatggc caagcagata ggttatgtct gttttctgag     2820

tgatgaagtc aggaagccct gtggctctgg aggccacttg tggttcattc ttttcccata     2880

tccttggctt ttagaaatgg ttaccttcag gacagtgcag ctgcatttat cagagcacta     2940

ttgctaagtt ttcttttctg gcttgtgttt ttctgggaca gtttagaatt gggaggccta     3000

ttctcataga acaccaaaaa tgatgttcag tgattcattt aacatacacc aatgtactct     3060

ggctgctggg gggacaacca taagcaagac atgcccaggg tttgccgtgg ctccagatct     3120

actccctgta ggagttcaag gatcacacaa acggtagtaa ccagggttgt gaatctgagt     3180

acaccctggc aaggcttctc ttcagactga agcagcaatt ctgccactac cagcagcaac     3240

caggacgtct gttctttgtg ggggccagat cagaagagag aggcccctgt gacgcccggg     3300

ctgcttggtc acaactctgt ccaattcaag gatgtttatc ggcctctctt agatcctgag     3360

tgagacaaat acagaaatga cccattccct gcccaccaga aactcagagg tgattgggga     3420

gactgacaca ggaaaatgaa cttaatcaag agagactgtg atatgtgcta agaagggtgt     3480

gagggaggga gagatgaatt ttccctggag ggatcctaga aagcattgtc atattgccat     3540

ctccattagc tcacttttaa acaactaggg tgctggaaga acctttgtct gagggtagtt     3600

catagctgga aatacttgga atattttcca gagtctctaa actctcatct tcccccacag     3660

atacacatcc aagctcacaa ataggagtag caattctagg tggtagggtt gtgtacggaa     3720

cccctggctg tctgcatata tctcagaatt accccaggac cattgtccca aagtctagag     3780

tctttacagg taggcaaaat ttgttttcaa tgcctgtgcc tcagctgctg tcacaaatac     3840

ccatcttagg atcccatcag cttcccatcc cccaccagac agccacagta ccctcacttt     3900

ctccctattg ttctttcaaa tcctgttctc aggaaagaaa ctgccactaa ttcattcaca     3960

ctaaggtgta aatgattgat aataggaatg agttacctct tcccacagac atttgttttt     4020

aagtatgaca gagcagggcc ttaatcccaa gggaaaaggt tatggaactg gagggggtga     4080

gctttctggg tagaaggaga cttcctgaat ttccttaaaa cccagtaaga gtaagacctg     4140

ttgttttgga aggtctgctc caccatctaa gagcactgtt tttttttttt tgttgttgtt     4200

gttgttttac ggtctctgag ggaatatagt aaaaatgcat atgcacgtgc aatttgcacg     4260

gcagcatttc accgattgtg gactgtattg gctaatgtgt ttcctggtct ttagatgcaa     4320

accattaata acactatctt atctcatagt tttttcaggg gtgcttcttg attagtaggg     4380

aattttgaac acctctttaa atacagctag aaaataaaac caatttgtaa agccacattt     4440

gcatatgatg ccagcctcac gcatttgtat atctccagaa attcaggtat gcctcaccaa     4500

tttgcccgtc tttaataaaa tcttgtgtta aaatttgcat cacgtcgcct tcctatgtat     4560

gacgaaacaa gaaacagaga tttccaattg ctcttttgtc ttcagacatt tagtaatata     4620

aagtacctat ttttatgctg aaatgtttat acaggtttat taatagcaag tgcaactaac     4680

tggcggcatg ccttgcaaca cattttgata tattagccat gcttccgggt aaaggcaagc     4740

cccaaactcc ttatcttttg cagtctctct gggatcagta aaagaaaaaa aaaataatgt     4800

gcttaagaag tgggactgta aatatgtata tttaactttg tatagcccat gtacctacct     4860

tgtatagaaa aataatttta aaaatttgaa tggaaggggg taaaggaagt catgaagttt     4920

ttttgcattt ttatttaaat gaaggaattc caaataactc acctacagat ttttagcaca     4980

aaaatagcca ttgtaaagtg ttaaaattta cgataagtat tctattgggg aggaaaggta     5040

actctgatct cagttacagt ttttttttcc tttttaattt cattattttg ggtttttggt     5100

ttttgcagtc ctatttatct gcagtcgtat taagtcctat tgctagaata ggttactaca     5160

aaaaaggtta tattctgaaa gaaaaataac tgacattata tataaccaat taatttaaag     5220

tattgccatt taaattacac actgagagca tgtcctatgc agacatagat ttttctgttc     5280

atttattttt cttcattgca gtggattgat ttgataaata gatgtgttga attactacat     5340

ttgctgtaca tattatttaa taaactttat tcagaattgc gtggcaaaaa aaaaaaaaaa     5400

aa                                                                    5402


<210>  1994
<211>  5985
<212>  DNA
<213>  homo sapiens

<400>  1994
gaagtcagcg ctgagtccca gaaaaacaga gcggggccag ctgcagcgtg tagtgcgagt       60

ggggcggacg cgcgcagccc gcccgcccgg cgaccagcaa ggagttggca tcctttggaa      120

gagttcgtga aagctttctg cccagagctc ctggaccaat gcatcttccc accaccttaa      180

accactgagc agttcagagc cccagttgca gacgacttgt cctgccacca ccatgagttc      240

tgaatgtgat ggtggttcca aagctgtgat gaatggcttg gcacctggca gcaatgggca      300

agacaaagac atggatccta caaaaatctg cactgggaag ggagcggtga ctctccgggc      360

ctcgtcttcc tacagggaaa ccccaagcag tagccctgcg agccctcagg aaacccggca      420

acacgaaagc aaaccaggtc tggagccaga gccttcttca gcagatgagt ggaggctttc      480

ttccagtgct gatgccaatg gaaatgccca gccctcttca ctcgctgcca agggctacag      540

aagtgtgcat cccaaccttc cttctgacaa gtcccaggat gccacttcct ccagtgcagc      600

ccagccggag gtaatagttg tccctctcta cctggttaat actgacagag ggcaagaagg      660

cactgccaga cctccaacac ctctggggcc tcttggctgc gtccccacaa tcccagcgac      720

tgcctctgcc gcctcacctc tgaccttccc gactctagat gatttcattc cccctcatct      780

gcagaggtgg ccccaccaca gccagccagc ccgcgcctct ggctcctttg cccccattag      840

ccagacgcca ccatccttct caccaccacc tccgctggtc cctcctgccc cggaggacct      900

ccgcagagtc tcggagcctg acctcacggg agctgtttcg agtaccgatt ccagtcctct      960

actaaatgaa gtttcttctt cccttattgg aactgattcc caagcctttc catcagttag     1020

caagccttca tccgcctatc cctccacaac gattgtcaat cctactattg tgctcttgca     1080

acacaatcga gaacagcaaa aacgactcag tagcctttca gatcctgtct cagaaagaag     1140

agtgggagag caggactcag caccaaccca ggaaaaaccc acctcacctg gcaaggctat     1200

tgaaaaaaga gcaaaggatg acagtaggcg ggtggtgaag agcactcagg acttaagcga     1260

tgtttccatg gatgaagtgg gcatcccact ccggaacact gagagatcaa aagactggta     1320

caagactatg tttaaacaga tccacaaact gaacagagat gatgattcag atctgtactc     1380

tcccagatac tcattttctg aagacacaaa atctcccctt tctgtgcctc gctcaaaaag     1440

tgagatgagc tacattgatg gtgagaaggt agtcaagagg tcggccacac tacccctccc     1500

agcccgctct tcctcactga agtcaagctc agaaagaaat gactgggaac ccccagataa     1560

gaaagtagac acaagaaaat atcgtgcaga gcccaagagc atttacgaat atcagcctgg     1620

caagtcttcc gttctgacca acgaaaagat gagctcagcc atcagcccta ctccggaaat     1680

ttcttcagag actcctggat atatatattc ttccaacttc catgcagtga agagggaatc     1740

agacggggct cctggggatc tcactagctt ggagaatgag agacaaattt ataaaagtgt     1800

cttggaaggt ggtgacatcc ctcttcaggg cctgagtggg ctcaagcgac catccagctc     1860

tgcttccact aaagattcag aatcgccaag acattttata ccagctgatt acttggaatc     1920

cacggaagaa tttattcgaa gacgtcatga tgataaagag atgagacctg ccagagccaa     1980

atttgacttt aaagctcaga cactaaagga gcttcctctg cagaagggag atattgttta     2040

catttataag caaattgatc agaactggta tgaaggagaa caccacggcc gggtgggaat     2100

cttcccacgc acctacatcg agcttcttcc tcctgctgag aaggcacagc ccaaaaagtt     2160

gacaccagtg caggttttgg aatatggaga agctattgct aagtttaact ttaatggtga     2220

tacacaagta gaaatgtcct tcagaaaggg tgagaggatc acactgctcc ggcaggtaga     2280

tgagaactgg tacgaaggga ggatcccggg gacatcccga caaggcatct tccccatcac     2340

ctacgtggat gtgatcaagc gaccactggt gaaaaaccct gtggattaca tggacctgcc     2400

tttctcctcc tccccaagtc gcagtgccac tgcaagccca cagcaacctc aagcccagca     2460

gcgaagagtc acccccgaca ggagtcaaac ctcacaagat ttatttagct atcaagcatt     2520

atatagctat ataccacaga atgatgatga gttggaactc cgcgatggag atatcgttga     2580

tgtcatggaa aaatgtgacg atggatggtt tgttggtact tcaagaagga caaagcagtt     2640

tggtactttt ccaggcaact atgtaaaacc tttgtatcta taagaagact gaaaaccatg     2700

gagattattt ttattggagg aggaagcatc attcatgaac cgatcttttt agttgagtca     2760

gtaggaaaat taatacagtg gataaagtaa gaagcaaaag acagggacag agaagtgttg     2820

tgtttaaaac ccaagcctgt ctaaggttac tgtgtattag acagggccga actagtgtgc     2880

tgagcaaaaa gaattgaagc aaattgtatt tacttagccg cttctgggag ccacttcagc     2940

ctttcccctc ccctccactt cttgggtaat ctgacctgaa gcatagtcca ggagcagagt     3000

tagccagaaa tgcctcctgc tgccccagcc ttagagagct cccatctcaa tcattgagcc     3060

tgaaggcttc aagcccaaga atgcaacaag acccccagcc tacatttctc agctcccctg     3120

gagccagctg atcctgtaac gctgctggag gtcagtctga gctaccaaga ctgtccctag     3180

acaaaggtgg agtcccccac actgcccaag accaaatccc tcactcaacc tgctgaggtg     3240

tggatgggga aacagaggca aaactgaggc acctgatgca ttcagcctgc tgtgcagcag     3300

tgccattgac tgccctgatg ttcagagaga aacgcacaca aggtttgccc atgagaattg     3360

gggagcagat ggccaagcag ataggttatg tctgttttct gagtgatgaa gtcaggaagc     3420

cctgtggctc tggaggccac ttgtggttca ttcttttccc atatccttgg cttttagaaa     3480

tggttacctt caggacagtg cagctgcatt tatcagagca ctattgctaa gttttctttt     3540

ctggcttgtg tttttctggg acagtttaga attgggaggc ctattctcat agaacaccaa     3600

aaatgatgtt cagtgattca tttaacatac accaatgtac tctggctgct ggggggacaa     3660

ccataagcaa gacatgccca gggtttgccg tggctccaga tctactccct gtaggagttc     3720

aaggatcaca caaacggtag taaccagggt tgtgaatctg agtacaccct ggcaaggctt     3780

ctcttcagac tgaagcagca attctgccac taccagcagc aaccaggacg tctgttcttt     3840

gtgggggcca gatcagaaga gagaggcccc tgtgacgccc gggctgcttg gtcacaactc     3900

tgtccaattc aaggatgttt atcggcctct cttagatcct gagtgagaca aatacagaaa     3960

tgacccattc cctgcccacc agaaactcag aggtgattgg ggagactgac acaggaaaat     4020

gaacttaatc aagagagact gtgatatgtg ctaagaaggg tgtgagggag ggagagatga     4080

attttccctg gagggatcct agaaagcatt gtcatattgc catctccatt agctcacttt     4140

taaacaacta gggtgctgga agaacctttg tctgagggta gttcatagct ggaaatactt     4200

ggaatatttt ccagagtctc taaactctca tcttccccca cagatacaca tccaagctca     4260

caaataggag tagcaattct aggtggtagg gttgtgtacg gaacccctgg ctgtctgcat     4320

atatctcaga attaccccag gaccattgtc ccaaagtcta gagtctttac aggtaggcaa     4380

aatttgtttt caatgcctgt gcctcagctg ctgtcacaaa tacccatctt aggatcccat     4440

cagcttccca tcccccacca gacagccaca gtaccctcac tttctcccta ttgttctttc     4500

aaatcctgtt ctcaggaaag aaactgccac taattcattc acactaaggt gtaaatgatt     4560

gataatagga atgagttacc tcttcccaca gacatttgtt tttaagtatg acagagcagg     4620

gccttaatcc caagggaaaa ggttatggaa ctggaggggg tgagctttct gggtagaagg     4680

agacttcctg aatttcctta aaacccagta agagtaagac ctgttgtttt ggaaggtctg     4740

ctccaccatc taagagcact gttttttttt ttttgttgtt gttgttgttt tacggtctct     4800

gagggaatat agtaaaaatg catatgcacg tgcaatttgc acggcagcat ttcaccgatt     4860

gtggactgta ttggctaatg tgtttcctgg tctttagatg caaaccatta ataacactat     4920

cttatctcat agttttttca ggggtgcttc ttgattagta gggaattttg aacacctctt     4980

taaatacagc tagaaaataa aaccaatttg taaagccaca tttgcatatg atgccagcct     5040

cacgcatttg tatatctcca gaaattcagg tatgcctcac caatttgccc gtctttaata     5100

aaatcttgtg ttaaaatttg catcacgtcg ccttcctatg tatgacgaaa caagaaacag     5160

agatttccaa ttgctctttt gtcttcagac atttagtaat ataaagtacc tatttttatg     5220

ctgaaatgtt tatacaggtt tattaatagc aagtgcaact aactggcggc atgccttgca     5280

acacattttg atatattagc catgcttccg ggtaaaggca agccccaaac tccttatctt     5340

ttgcagtctc tctgggatca gtaaaagaaa aaaaaaataa tgtgcttaag aagtgggact     5400

gtaaatatgt atatttaact ttgtatagcc catgtaccta ccttgtatag aaaaataatt     5460

ttaaaaattt gaatggaagg gggtaaagga agtcatgaag tttttttgca tttttattta     5520

aatgaaggaa ttccaaataa ctcacctaca gatttttagc acaaaaatag ccattgtaaa     5580

gtgttaaaat ttacgataag tattctattg gggaggaaag gtaactctga tctcagttac     5640

agtttttttt tcctttttaa tttcattatt ttgggttttt ggtttttgca gtcctattta     5700

tctgcagtcg tattaagtcc tattgctaga ataggttact acaaaaaagg ttatattctg     5760

aaagaaaaat aactgacatt atatataacc aattaattta aagtattgcc atttaaatta     5820

cacactgaga gcatgtccta tgcagacata gatttttctg ttcatttatt tttcttcatt     5880

gcagtggatt gatttgataa atagatgtgt tgaattacta catttgctgt acatattatt     5940

taataaactt tattcagaat tgcgtggcaa aaaaaaaaaa aaaaa                     5985


<210>  1995
<211>  5795
<212>  DNA
<213>  homo sapiens

<400>  1995
gagcagcggc agcagcagcg gaccccggcg gcggcggcgg cgcgcggtcc cagccaggcg       60

gccccggtgt cccggccccg gtggatgcac ggctggggag gagcccatgg gccggagctg      120

aggctgcccg gggcggcggg gcgcggggca gggggcgcgg tcgaggcccg gaggcggcgg      180

cgcaggagga agcggaggag gtcgggcgct cggggcccgg gaggcgggcc gcgcagcgcc      240

gcagccccgg gctcgccatg ctcctggcct cggccgtggt ggtctgggaa tggctgaacg      300

agcacggccg ctggcgtccc tacagcccag cggtgagcca ccacatcgag gcggtggtcc      360

gcgccggccc ccgcgcgggg ggcagcgtgg tgctgggcca ggtggacagc cgtctcgcgc      420

cctacatcat cgacctgcag tccatgaacc agttccgcca agacacggga actctccgcc      480

cagttcgccg caactactac gacccctcct cggcccctgg gaagggcgtg gtgtgggagt      540

gggagaacga caatggctcc tggacgccct acgacatgga agtgggcatc accatccagc      600

atgcctatga gaagcagcac ccctggatcg acctcacttc cattggcttt agctacgtaa      660

ttgacttcaa caccatgggc cagatcaacc gtcagaccca gcgccaacgc cgcgtccgcc      720

ggcgcctcga cctcatctac cccatggtca cagggacctt gcctaaggct cagtcctggc      780

cagtcagccc tgggccagcc acctcgcccc ccatgtcccc ctgctcctgt ccccagtgtg      840

tcttggtgat gagtgttaag gcagccgtgg tcaatggcag cactgggccc ctacagctgc      900

cagtgacccg caagaacatg ccgcctcctg gagtggtcaa gctaccccca ctgccaggct      960

ctggggccaa gccactggac agcacaggca ccattcgagg cccactgaag accgccccat     1020

cgcaggtgat ccggagacaa gcctccagca tgcccactgg gacaaccatg ggctctcctg     1080

ccagtccccc aggacccaac agcaagaccg gaagggtggc cctggccacc ttgaatcgta     1140

ccaacctgca gcgactggcc attgcccagt cccgggtgct gatcgcctct ggggtcccca     1200

cagtcccagt gaagaaccta aatgggtcca gtcctgtcaa ccctgccttg gcaggaatca     1260

ctgggatcct catgagtgca gcggggctgc ctgtgtgtct caccaggcca ccaaagctgg     1320

tcctacaccc accccccgtc agcaagagtg aaataaaatc catcccaggg gtttccaaca     1380

caagccgcaa gaccaccaaa aaacaagcca agaaaggtaa aaccccagag gaagtgctaa     1440

aaaaatatct acagaaagtc cggcacccac cagatgagga ctgcaccatc tgtatggaac     1500

gcctcacggc cccctcaggc tacaagggcc cgcagcctac ggtaaaacct gacctggtag     1560

ggaagctgtc cagatgcggc cacgtctacc acatctactg cttggttgcc atgtacaaca     1620

atgggaacaa ggatggaagt ttgcagtgtc caacctgcaa gaccatttat ggggtgaaga     1680

caggcaccca acctccaggg aagatggagt accacctcat cccccactcc ttgcctggcc     1740

acccagactg caaaaccatc cggatcatct acagcatccc ccccggcatt cagggaccgg     1800

aacacccgaa tcctgggaag agtttcagcg cccgaggctt cccacgacac tgttaccttc     1860

cggacagcga gaaagggaga aaagttctga agctgctgct cgtggcctgg gatcgccgcc     1920

tcatttttgc cattggcacc tccagcacca caggcgagtc agacaccgtc atctggaatg     1980

aggtccacca caagacagag tttggctcta atctcactgg ccatggctac ccagatgcca     2040

attacctgga taatgtgctg gctgaactgg ctgcccaggg catctctgag gacagcactg     2100

cccaggagaa ggactgaggc cagaaaagct ttgaggtggg aggggccatg gagactgcag     2160

gacaggaagt gaggagagtg agtcaatgta gaagaagttg gtgtcctgcc ctcccaactt     2220

tctatcctcc cctcctgccc tgtgtccatc cctcatccct cccaaccaca gtgggagcca     2280

gactgaatat agcgacatca ttcataaatc tcatccaaca caaagggaga tgggatgagg     2340

gccatcctgg gtctgttccc atggagtttt tggtgctggg taggcaggaa tcccctccct     2400

accccacctc ccaagtaggg gcatggtcag cacacctagg gtatgggcag tgcttaggca     2460

ctccatatcc tggctttggg aagccggggt ttcttgcctc agccggcttc ttgctacttc     2520

cactctgctt tgagactgga gtttctgcta ttctccctct gctggaggca gggagctctc     2580

actgtgcaag gttggggggt gggcaaaggg gtgaatcact aaactgctgt gacatcagaa     2640

actgatgcct tggtgtagag caaggaagca cttcttccca agagggtcgg agaaggaaaa     2700

gcctctggga gcacattctg ctgtcatcac agtccttggc ttctctgggc cctcctctcc     2760

tcctcacagc tctcacctgt ccaaagaggc atctggttct ctcatgtgga tggatggact     2820

ctggggttcc tctttggagt ggcatcccat gatgctgttt ctagaccctc tctgatcaaa     2880

ccagagcctg catcccactg agcatctgaa ctgtcctcag ggagaggagc ccacagcctt     2940

cttcccaact cattctagac cagctcaaag attccatgag tttcatcgag tcactgtgag     3000

tggagcccat gctgggctct gtgccctctg tgtctgtgca tgcgcgtgtg tgtgtgggcg     3060

tgtgtgcatt gctgggccag cttgaaggga aggcccgtca tgtccctgca ctctgttttg     3120

caagatgcca aaccccagtt ctgatggggc tccaacagcc aggctgtggt cctttgacgt     3180

tcctcacctg ttgccaacct atcccgtagt gaactgaaac cccaatgaag acagaactgt     3240

gcctggggag atgcaatgag gtgagggctg aactcatcct tttatatttc ttttcaagat     3300

tggatcagag ctcatctcca tccagtcttg tttctatgaa ggcttcaatc tgtttccatg     3360

caaatttgct aatcagagcc cagagctgct gggtccctca tctccctcat ctattataga     3420

ttgacttaca gcagggagag aatctcttta gctcattcct aatggagttg ggatcacaat     3480

atggtctggt ccaatctgca tcttgttgtg tcccaagacc ctatctcctc cccaacattc     3540

ttattgcctt tggctcccag taaggaacga attgggggcc agggaggaga acagggggga     3600

tcaagaaggg aaacccaatt ccccctttga aagtgggttc tttgaactat gtgtttgggg     3660

gaagttcctc tggatactaa tttgaattta tatacctcat gttttggggg tttgacgtat     3720

atatatatat atatatatgc atatatattt cataatattt ggaaggtttt tgatgctaga     3780

aaaatggaaa caagagaacc ttcaaaaatg gtacttagat gggaactgga ggccaatctt     3840

tcataaagcc agccccatag ctgcttgctg ttaggcctcc agccattttg acattggggt     3900

ggatagtcga ttcacctgcc tgtcagtcga ttcacctgcc tgtcacccag ttctgtggat     3960

gtgctggtgc tgagcctttg ctctctttcc aaatggttac agggatgttg atcagctcca     4020

ccagagggag ctctgatggg aggaattgct ctgccatcct tgtccctgtg tctcctgtcg     4080

gcaggcagcc attgtatctc accagcagac caggagactg gtcccaaggt tactgcacca     4140

cagggcaatt tcctgccata gttaggaagg aaacacctga actaaatgga agagacatcc     4200

ctgcggtgtt taatatcaca cccatgccct ttgtcaggtt accatgtaca gagattactt     4260

ggagagcctc atgccgtctc taccttcgca cactggtcaa gtatctgctg agcttcttgg     4320

ccgcaaggat gcagaaatag gctgagggtc catgggaaga aagacacaat gaggcagtag     4380

gaggtgggga agaaaagaag acagactttc aaaatggaat taggcactgg ggagagatca     4440

gtttccccac atcagggaga agaaggtata ggtggggaag ggggtggcca ggagcagaag     4500

gaagaagact caagatggaa agggagccgc tgtgcctgtg gcaataccac ttggagaggt     4560

cgacttcata ccttcaagcc ttttcccctg ggcttttgat tgtgtctgtg ccccctttct     4620

tgtcctctct gcagatgccc agtaggggct acctcatcct cgtgctgttc ttgtgtggct     4680

ttctgggcag tagggatctt gaatttcctt tctaacactg tgcccggcaa ggcggggagc     4740

attcctctgc cctttgtctt gtgccaacct ggaaaggtgc agtctagatt tcagtgagaa     4800

ccctgccagc tgagccctgt gcatctacta ccttgacaca gagtgttttc ccactagaag     4860

ctctgctctg ctctcctggc ccaagtaggg gattccatgc cttccctttc atggtcttag     4920

caccagcagc ctagtttctc ccttccagag tctccaggga tgacaaattg gattggagac     4980

aaacctcgtc agatgctcat cccctaaaag gttaattgtg tatttgtggc tgcgtgtgcc     5040

tttgtgtttt cattctcttc ccatttttgt acattttggt cttctctgtg gttttatact     5100

tggtcaaaag tactcgtctt ggtattgcac tgttgtgtgc atgagaaaac tgggggaagg     5160

ctcactggta caagaaagga cccctgaccc ctttccttct ctgtggtccc cggcattaga     5220

ttgggggttc tgggagaggc aggtgaatgt cctaagtgaa ttgttctgtt tgtaactgga     5280

atgtttttga agtctttggt gttgctccgt gaaaggacat cgccacctgg tgctcatgag     5340

gtgtctttgc agaacaataa atggcaaatg aacaaccaca aaattgttac tcttgttggc     5400

cttctgctgt ttgtagatta gtgcacctat ctgtgaggga tttgggttac ctccctgagt     5460

ctgtaagcaa ccacaagccc tgccactggg tgggggaagt ccctccccaa ccacttaaaa     5520

acaaattttc cacatattac ccacccacac atttgacctg gctagacttt gtttgcctaa     5580

aggaacagac cacattgctg ggaaaatgag taagtgaacg tgtgggagaa aaacactttt     5640

agaatcacga atattcactt ttaaaggtct ctttgcctgg ctgcaatata gtgtgtgttt     5700

aaattattta caggctgttg tttctcaaat aaatgtttaa tattaatcat tcccaaactg     5760

acaagaacac aaaaataaaa tgcaaataca gagcc                                5795


<210>  1996
<211>  4726
<212>  DNA
<213>  homo sapiens

<400>  1996
gaagccgctc tgtgacccac ctctgaatcc cacaaaactg caccagagag ccgggcgcaa       60

gatgaaccag caccctgtcg gctcaagatg caccagaccc tctgcctgaa ccccgagagc      120

ctgaaaatgt ctgcgtgcag tgactttgtg gagcacatct ggaaacccgg gtcctgcaag      180

aactgcttct gcctgcggag cgaccaccag ctggtggccg gccctcccca gcccagagcg      240

ggcagcctgc cccctccacc gcgcctgcct cccaggcctg agaactgccg cctggaagat      300

gaaggtgtga acagctcacc ttactccaag cccacaattg ccgtgaagcc caccatgatg      360

agctccgagg cctctgatgt gtggacagag gccaacctga gtgccgaagt ctcgcaggtc      420

atctggagac gagcccctgg caagctcccc ctcccgaagc aggaggatgc ccccgtcgtc      480

tacctgggca gcttccgagg tgtacagaag cctgctggtc cctctacctc ccctgatggc      540

aattctcgct gtcccccagc ttacaccatg gtcggcctgc acaaccttga gccccgcggc      600

gagaggaaca ttgccttcca cccggtgagc ttcccggagg agaaggctgt gcacaaagaa      660

aaaccctcat ttccttacca agaccggccc tccacccagg agagcttccg ccagaaactg      720

gctgcctttg ctgggaccac atctggctgt caccagggcc ctgggcccct gcgggaatcc      780

ctgccctcgg aggatgacag tgatcaaagg tgctcgccct ccggggacag cgagggtgga      840

gagtactgct ccatcctgga ctgctgccct gggagccctg ttgccaaggc tgcctcccag      900

actgcaggtt cccggggcag gcatggtggc agggactgct cacccacgtg ctgggagcag      960

gggaagtgtt ccgggcccgc agagcaggag aagcggggcc cgagcttccc caaggagtgc     1020

tgtagccagg gccccactgc ccacccatcc tgcctgggcc ccaagaaact gtccctcacc     1080

tcggaggctg ccatttcttc cgacggcctc tcttgtggca gcggcagcgg cagcggcagc     1140

ggcgccagta gccccttcgt cccccacctc gagagtgatt actgctccct catgaaggaa     1200

cctgccccag agaagcagca ggaccctggc tgcccagggg tgacccctag cagatgcctt     1260

gggctgacgg gggagcccca gcccccggcc cacccccggg aggctacaca gcctgaaccc     1320

atctatgctg agagcaccaa gaggaagaag gcagctccgg tgccttccaa gtcacaggcc     1380

aagatagaac atgcagctgc tgcccagggc caaggccagg tatgcacagg taatgcctgg     1440

gcccagaaag cagcatctgg ctggggccgg gacagcccag acccaactcc ccaggtgtca     1500

gccaccatca cagtcatggc ggcccacccg gaagaggacc atcggacgat ctacctgagc     1560

agccctgact ctgcagtggg ggtgcagtgg ccacgagggc ctgtgagcca gaactccgag     1620

gtaggtgaag aggagacttc ggctgggcag gggctgagct ccagggaaag ccatgctcac     1680

agtgccagcg agagcaagcc caaggagagg cccgccattc cccccaagtt gtccaagagt     1740

agccctgtag ggtccccggt gtcaccgtct gctggagggc ccccagtgtc accgctggct     1800

gaccttagtg atgggagctc tggcggcagc agcattgggc cccagcctcc atcccaaggt     1860

cctgctgacc ccgctccttc ctgccggacc aacggtgtcg ctatcagtga cccatccagg     1920

tgtccccagc ctgccgcctc gtcagcctcg gaacagaggc ggcccaggtt ccaggcaggc     1980

acctggagtc gtcagtgccg gatagaggaa gaagaggagg tggagcagga attgctgagt     2040

cacagctggg gaagagagac caaaaatggc cccacggacc attcaaactc cacgacctgg     2100

caccgtctcc accccacaga tggctcctct gggcagaaca gcaaagttgg gaccgggatg     2160

agcaaatccg cctcttttgc ctttgagttc cccaaggaca gaagtgggat tgagacattc     2220

tcacctcctc ctccgcctcc aaagtcgcgg caccttctaa aaatgaacaa gagcagctct     2280

gatttggaaa aagtgagcca gggctctgca gaaagcctca gcccatcctt caggggtgtc     2340

cacgtcagct tcaccaccgg ctccacggac agcctggcct cagactctag gacctgcagc     2400

gatggaggtc cctcgtctga gctggctcac tcgcccacca acagcgggaa gaagctcttt     2460

gctcccgttc cgtttccttc aggctccact gaggacgtgt cccccagtgg cccccagcag     2520

ccccctccac tcccccagaa aaagatagtg agccgggcag cctcttcacc ggatggcttc     2580

ttctggaccc aaggctcccc caagcccgga acagcaagcc ccaagctgaa cctaagccac     2640

tcggaaacca acgtccacga cgaatctcac tttagctatt cgttgagccc cgggaaccgc     2700

caccatcctg tcttctcctc ttccgatcct ctggagaaag ctttcaaagg cagtggccac     2760

tggcttccgg cagcagggct ggcgggcaac agaggcggct gcgggagccc tggcctccag     2820

tgcaaagggg ccccctccgc ctcatcctcc cagctgagcg tgtccagtca agcctccacc     2880

gggagcaccc agcttcagct gcacggtctc ctgagcaaca tcagcagcaa ggagggcacc     2940

tatgccaagc tggggggact ctacacccag tccctggccc gccttgtagc caaatgtgag     3000

gacctcttca tgggcggcca gaaaaaggag ctccacttca atgagaataa ctggtcgctc     3060

ttcaagctga cttgtaacaa gccctgctgt gactcggggg atgccattta ttactgtgcc     3120

acctgctctg aggaccccgg cagcacctat gctgtgaaaa tctgcaaagc ccctgagccc     3180

aaaacagtct cctactgcag cccgtccgtg cccgtgcact ttaacatcca gcaggactgc     3240

ggccacttcg tcgcctcggt gccgtccagc atgctcagct cccccgacgc gcccaaggac     3300

cctgtgcctg ccctgcccac acacccccct gcccaggagc aggactgcgt ggtggtcatc     3360

acccgagagg tgccacatca gaccgcctcc gacttcgtgc gggactcggc ggccagccac     3420

caggcggagc ccgaggcgta cgagcggcgc gtgtgcttcc tgcttctgca actctgcaac     3480

gggctggagc acctgaagga gcacgggatc atccaccggg acctgtgcct ggagaacctg     3540

ctgctggtgc actgcaccct ccaggccggc cccgggcccg cccccgcccc cgccccggct     3600

cccgcccccg ccgccgccgc gcctccctgc tcctctgccg ccccgcctgc tggtggcact     3660

ctcagccccg cagccggccc cgcctccccg gaagggcccc gggagaagca gctgccccgg     3720

ctcatcatca gcaacttttt gaaggccaag cagaagccgg gcggcacccc aaacctgcag     3780

cagaagaaga gccaggcccg gctggccccc gagatcgtgt ctgcttccca gtaccgcaag     3840

ttcgatgagt tccagacagg catcctcatc tacgagctgc tgcaccaacc caacccgttc     3900

gaggtgcgcg cccagctgcg ggagagagac taccggcagg aggacctgcc gccgctgccc     3960

gcgctgtccc tctactcacc cggcctgcag cagctggcac atctgctact ggaggccgac     4020

cccatcaagc gtatccgcat cggcgaggcc aagcgcgtgc tgcagtgcct gctgtggggg     4080

cctcggcgcg agctggtgca gcagccgggc acctcggagg aggcgctgtg cggcacgctg     4140

cacaactgga tcgacatgaa gcgggccctg atgatgatga agtttgcgga gaaggcggtg     4200

gatcgcaggc ggggcgtgga gctggaggac tggctttgct gccagtacct ggcgtctgcg     4260

gagcccgggg ccctcttaca gtcgctgaag ctcctgcagc ttctgtgagc caagccccag     4320

cctgcaccgt cgctgcccct tccctgccta accctttcct gtctcgcctt ggaagcaccc     4380

atgtctccct gggaaatggt acagatgact gggatacctg gatgtaaaat atataaatat     4440

atatatagaa aatacatata ccatatataa atatgaaaga ctaaggatgc tgttgcccgt     4500

ccacactcgt ctcctctctg cactaagtcc tccctgtttt cttctgtaat tatacacatt     4560

tccagttcca tgcaacgtcc tgaggacagt tctgtgaact gaatgcagcc tggacactgg     4620

cctcaatacc ttgtttagga tttcttcacc cttttgtcaa attgttattt aaagaaaaaa     4680

aaaaaagaag aaaattccat taaaattttt tttggttgag tcatga                    4726


<210>  1997
<211>  2926
<212>  DNA
<213>  homo sapiens

<400>  1997
aagagtgtgg atagtgggct ctgcggataa ctcagacgcc attaagctgg ggaatccaaa       60

ctctaaaaga aggacgcatt ttaggtaaga tctagtggct agatcttcag ggtgggcttc      120

gttcttgtgg aaatcagtca agaaagatcg gattcgcggt tatttatgca aatcatctgg      180

gtggattgtg tacggagtta aactgcgcct tctggaccgg gtctgaacaa tggagactgc      240

gctagcaaaa acgccacaga aaaggcaagt tatgtttctt gctatattgt tgcttttgtg      300

ggaggctggc tctgaggcag ttaggtattc cataccagaa gaaacagaaa gtggctattc      360

tgtggccaac ctggcaaaag acctgggtct tggggtgggg gaactggcca ctcggggcgc      420

gcgaatgcat tacaaaggaa acaaagagct cttgcagctt gatataaaga ccggcaattt      480

gcttctatat gaaaaactag accgggaggt gatgtgcggg gcgacagaac cctgtatatt      540

gcatttccag ctcttactag aaaatccagt gcagtttttt caaactgatc tgcagctcac      600

agatataaat gaccatgccc cagagttccc agagaaggaa atgctcctaa aaatcccaga      660

gagcacccag ccagggactg tgtttccctt aaaaatagcc caggactttg acataggtag      720

caacactgtt cagaactaca caatcagccc aaattcacac tttcatgttg ctacgcataa      780

tcgcggagat ggcagaaaat acccagagct ggtgctggac aaagcgctgg accgggagga      840

gcggcctgag ctcagcttaa cactcactgc actggacggt ggggctccgc ccaggtccgg      900

gaccaccaca attcgcattg tcgtcttgga taataatgac aacgcccccg aatttttaca      960

atcattctat gaggtacagg tgcccgagaa cagccccctt aactccttag ttgtcgttgt     1020

ctccgctcga gatttagatg caggagcata tgggagtgta gcctatgctc tattccaagg     1080

cgatgaagtt actcaaccat ttgtaataga cgagaaaaca gcagaaattc gcctgaaaag     1140

ggcattggat ttcgaggcaa ctccatatta taacgtggaa attgtagcca cagatggtgg     1200

gggcctttca ggaaaatgca ctgtggctat agaagtggtg gatgtgaatg acaacgcccc     1260

tgaactcacc atgtctacgc tctccagccc taccccagaa aatgccccgg aaactgtagt     1320

tgccgttttc agtgtttctg atccagactc cggggacaac ggtaggatga tttgctccat     1380

ccagaatgat ctcccctttc ttttgaagcc cacattaaaa aacttttaca ccctagtgac     1440

acagagaaca ctggacagag agagccaagc cgagtacaac atcaccatca ctgtcaccga     1500

catggggaca cccaggctga aaaccgagca caacataacg gtcctggtct ccgacgtcaa     1560

tgacaacgcc cccgccttca cccaaacctc ctacaccctg ttcgtccgag agaacaacag     1620

ccccgccctg cacatcggca gtgtcagcgc cacagacaga gactcaggca ccaacgccca     1680

ggtcacctac tcgctgctgc cgccccagaa cccacacctg cgcctcgcct ccctggtctc     1740

catcaacgcg gacaacggcc acctgtttgc cctcaggtcg ctggactacg aggccctgca     1800

ggcgttcgag ttccgcgtgg gagccacaga ccgcggctcc ccggcgctga gcagcgaggc     1860

gctggtgcgc gtgctggtgc tggacgccaa cgacaactcg cccttcgtgc tgtatccgct     1920

gcagaacggc tcggcgcctt gcaccgagct ggtgccccgg gcggccgagc cgggctacct     1980

ggtgaccaag gtggtggcgg tggacggtga ctcgggccag aacgcctggc tgtcgtacca     2040

gctgctcaag gccacggagc ccgggctgtt cagcatgtgg gcgcacaatg gcgaggtgcg     2100

caccgccagg ctgctgagcg agcgcgacgc ggccaagcac aggctggtgg tgctggtcaa     2160

ggacaatggc gagcctccgc gctcggccac cgccacgctg cacgtgctcc tggtggacgg     2220

cttctcccag ccctacctgc cgctgccgga ggcggccccg gcccaggccc aggccgactc     2280

gctcactgtc tacctggtgg tggcattggc ctcggtgtcg tcgctcttcc tcttttcggt     2340

gctcctgttc gtggcagtgc ggctgtgcag gaggagcagg gcggccccgg tcggtcgctg     2400

ctcggtgccc gagggcccct ttccagggca tctggtggac gtgagcggca ccgggaccct     2460

atcccagagc taccactacg aggtgtgttt gaccggagac tcaggggccg gcgagttcaa     2520

gttcctgaag ccgattattc ctaacctttt gccccagggc gctggtgaag aaatagggaa     2580

aactgctgcc ttccggaata gctttggatt aaattagaga tctcgtgatg acgcgttgtt     2640

ttctgccatt tatcccaaac tttttcagat ctagaattcg agagtgtcat ggacaaaaat     2700

ttcaccttga gattgagctt ttatttccct ttttaatgga tttgtctgtt gaacttcatg     2760

ctgtccaagt gttgaaaagt caattttatt tcattgcatt tatttacata gtgtcattcc     2820

aaatccatgc atgctgttga ttttcctgag atttttttct cttcttgttg gtatttgttg     2880

tgataaacca ccttaataaa atcaagtatt aattttattt tcaaaa                    2926


<210>  1998
<211>  5653
<212>  DNA
<213>  homo sapiens

<400>  1998
gacaaagaga actaatgctt tgtgctgatt catatttgaa tcgaggcatt gggaaccctg       60

tatgccttgt ttgtggaaag aaccagtgac accatcactg agcttcctaa aagttcgaag      120

aagttagagg actatacact ttcttttgaa cttttataat aaatatttgc tctggttttt      180

ggaacccagg gctgttagag gggtgagtga caagtcttac aagtggcctt attccaactc      240

cagaaattgc ccaacggaac tttgagatta tatgcaatcg aaagtgacag gaaacatgcc      300

aactcaatcc ctcttaatgt acatggatgg gccagaagtg attggcagct ctcttggcag      360

tccgatggag atggaggatg ccttgtcaat gaaagggacc gctgttgttc cattccgagc      420

tacacaagaa aaaaatgtca tccaaatcga ggggtatatg cccttggatt gcatgttctg      480

cagccagacc ttcacacatt cagaagacct taataaacat gtcttaatgc aacaccggcc      540

taccctctgt gaaccagcag ttcttcgggt tgaagcagag tatctcagtc cgcttgataa      600

aagtcaagtg cgaacagaac ctcccaagga aaagaattgc aaggaaaatg aatttagctg      660

tgaggtatgt gggcagacat ttagagtcgc ttttgatgtt gagatccaca tgagaacaca      720

caaagattct ttcacttacg ggtgtaacat gtgcggaaga agattcaagg agccttggtt      780

tcttaaaaat cacatgcgga cacataatgg caaatcgggg gccagaagca aactgcagca      840

aggcttggag agtagtccag caacgatcaa cgaggtcgtc caggtgcacg cggccgagag      900

catctcctct ccttacaaaa tctgcatggt ttgtggcttc ctatttccaa ataaagaaag      960

tctaattgag caccgcaagg tgcacaccaa aaaaactgct ttcggtacca gcagcgcgca     1020

gacagactct ccacaaggag gaatgccgtc ctcgagggag gacttcctgc agttgttcaa     1080

cttgagacca aaatctcacc ctgaaacggg gaagaagcct gtcagatgca tccctcagct     1140

cgatccgttc accaccttcc aggcttggca gctggctacc aaaggaaaag ttgccatttg     1200

ccaagaagtg aaggaatcgg ggcaagaagg gagcaccgac aacgacgatt cgagttccga     1260

gaaggagctt ggagaaacaa ataagggcag ttgtgcaggc ctctcgcaag agaaagagaa     1320

gtgcaaacac tcccacggcg aagcgccctc cgtggacgcg gatcccaagt tacccagtag     1380

caaggagaag cccactcact gctccgagtg cggcaaagct ttcagaacct accaccagct     1440

ggtcttgcac tccagggtcc acaagaagga ccggagggcc ggcgcggagt cgcccaccat     1500

gtctgtggac gggaggcagc cggggacgtg ttctcctgac ctcgccgccc ctctggatga     1560

aaatggagcc gtggatcgag gggaaggtgg ttctgaagac ggatctgagg atgggcttcc     1620

cgaaggaatc catctggata aaaatgatga tggaggaaaa ataaaacatc ttacatcttc     1680

aagagagtgt agttattgtg gaaagttttt ccgttcaaat tattacctca atattcatct     1740

cagaacgcat acaggtgaaa aaccatacaa atgtgaattt tgtgaatatg ctgcagccca     1800

gaagacatct ctgaggtatc acttggagag acatcacaag gaaaaacaaa ccgatgttgc     1860

tgctgaagtc aagaacgatg gtaaaaatca ggacactgaa gatgcactat taaccgctga     1920

cagtgcgcaa accaaaaatt tgaaaagatt ttttgatggt gccaaagatg ttacaggcag     1980

tccacctgca aagcagctta aggagatgcc ttctgttttt cagaatgttc tgggcagcgc     2040

tgtcctctca ccagcacaca aagatactca ggatttccat aaaaatgcag ctgatgacag     2100

tgctgataaa gtgaataaaa accctacccc tgcttacctg gacctgttaa aaaagagatc     2160

agcagttgaa actcaggcaa ataacctcat ctgtagaacc aaggcggatg ttactcctcc     2220

tccggatggc agtaccaccc ataaccttga agttagcccc aaagagaagc aaacggagac     2280

cgcagctgac tgcagataca ggccaagtgt ggattgtcac gaaaaacctt taaatttatc     2340

cgtgggggct cttcacaatt gcccggcaat ttctttgagt aaaagtttga ttccaagtat     2400

cacctgtcca ttttgtacct tcaagacatt ttatccagaa gttttaatga tgcaccagag     2460

actggagcat aaatacaatc ctgacgttca taaaaactgt cgaaacaagt ccttgcttag     2520

aagtcgacgt accggatgcc cgccagcgtt gctgggaaaa gatgtgcctc ccctctctag     2580

tttctgtaaa cccaagccca agtctgcttt cccggcgcag tccaaatccc tgccatctgc     2640

gaaggggaag cagagccctc ctgggccagg caaggcccct ctgacttcag ggatagactc     2700

tagcacttta gccccaagta acctgaagtc ccacagacca cagcagaatg tgggggtcca     2760

aggggccgcc accaggcaac agcaatctga gatgtttcct aaaaccagtg tttcccctgc     2820

accggataag acaaaaagac ccgagacaaa attgaaacct cttccagtag ctccttctca     2880

gcccaccctc ggcagcagta acatcaatgg ttccatcgac taccccgcca agaacgacag     2940

cccgtgggca cctccgggaa gagactattt ctgtaatcgg agtgccagca atactgcagc     3000

agaatttggt gagccccttc caaaaagact gaagtccagc gtggttgccc ttgacgttga     3060

ccagcccggg gccaattaca gaagaggcta tgaccttccc aagtaccata tggtcagagg     3120

catcacatca ctgttaccgc aggactgtgt gtatccgtcg caggcgctgc ctcccaaacc     3180

aaggttcctg agctccagcg aggtcgattc tccaaatgtg ctgactgttc agaagcccta     3240

tggtggctcc gggccacttt acacttgtgt gcctgctggt agtccagcat ccagctcgac     3300

gttagaagga aaaaggcctg tgtcatatca acacttatct aacagcatgg cacaaaagag     3360

aaactatgag aattttattg ggaatgcaca ttatcgacca aatgacaaaa aaacttgatt     3420

cactaattag ggggaaaaaa ggtcttggtg gatgtcagtg cttactcccc atgaaattaa     3480

attttacttc atcctttgag aagcgaatgg tgaaagctac tgaaataagc tgtgattgta     3540

ctgtacataa aacatatgag gaatctgcaa ggaacactac agttgtgtaa agttgttctg     3600

ttaacttttg taccaaatag caatacaaac tagttggaac agttggaact tacatacatg     3660

gggactggaa atctctattt tgtccctgaa taatattttt cttagaattg accaaataag     3720

aagtggaatt tttgcatact tgagcgctgc tgaaaagaaa tcatttgggt tgggtggggc     3780

gggatggggg aaaagtatat aatgcttgca cctcaggtaa aaatctgtaa atatctaagt     3840

tgtaaacctg cttgttcaaa tactgtgtgt attccttttc tctaatgcag ctcatcactt     3900

ggagcagttt ctgctattgt gctctttcat ttaaaatgta tgtttttttt tttttaaact     3960

gtcaatgatt ttgtattatg ttgaatccac ccaaatctat tgttgtctta aaattgttaa     4020

tggaagtatt gaccctctat gatatgtgct gcagatatcg aggtcagcca ttcggaagct     4080

ggcagcattt tatcgcaact ttgagcatct cagatgggga aggcaccttc ttcctcgcct     4140

ctccagattg tcctggaacc tccaggatcc ttgactgagg gcgttgggat ggcttgtagg     4200

atttttaaga gagtgtgtct acagacaagc attttctctg tagagcagcc acacgttgta     4260

taaacataaa ctgtatgtgc agttatttaa atttgtttct gtcaaattaa tcatttttgt     4320

tggacgattc agtggcgggg gggttttgcc taaattagta tataaaaaca aaaatgctaa     4380

attatatctg tgaattgcag gtattgggga acagttttaa gggaaatttt ggggggaaca     4440

ttttaggttt gtatttggta gtcttaatgt atctggcatt tgggtgaact gtggacatac     4500

tagagttgat tatagacaca ttgattttga ataaggaact gctggccgag cccgctggga     4560

gtctagaaag agaaaatctg tttctagacc tcagttattt tcccattttt ggttgttttg     4620

aagcagtaac atttttctca gtgcacatgc aatttgggtt ttagagaaga tggccaccag     4680

ctggcttcct agatatttta aacttttgtt ctttaatatg ctgtccatgg ctgagtttat     4740

tagtacatgg gcttagtgac cacaaaatat tttattaaga aactgtttca aaaataaatt     4800

tgcactgttc atttttctgg cctcgctgtt ctccatagag caagggtaat cctagaaaaa     4860

attttttttt tttaaattat gcaacgtaag atgtcctcct tgatagaagt cttagctcct     4920

gtgttacaag ggagaactca tttgagatca gtctgttggc attgcaatga agtgctttgt     4980

atcaggaaag tgtacactat tgaccttttt tcctgttcac aagctgagcc atatgtacat     5040

aatctagatt ttgttttcat agttttgcac ttttatagcc tatttttgaa gattaacaca     5100

tttgcaagat gattgactca atctttgcct aatccaatga gtgttacaga gagcttgctg     5160

tgactagaac cataaatctt aaagggggta tgtgataata gagggctgga atttaaacct     5220

gtatttaaaa aaaagaatca ccaaatctat ttgaaaacaa gtcgatttgt attatgctgg     5280

aattttttgg gctttcagat ttctcttttt aaccacattt ctgaatgtat aaaaatacca     5340

attattttcc tacagccctt tgtacttcaa aatatgtttt tgtgtccatc agtattaact     5400

attggtatac tactggtttt atattttttt ttctttgaga caacagtaca tataatagag     5460

gtacaattcg ttggattttt gtttatgtat ttatttcatt ccagtttgat ttattttaat     5520

tgttgatact taagttgtcg aacagtagac attacttgtt ttatttatga tatatttcag     5580

cttaaagtta tgttattata tgtggaagtg taaatataga tttggtgttt tgcaaaaaaa     5640

aaaaaaaaaa aaa                                                        5653


<210>  1999
<211>  1352
<212>  DNA
<213>  homo sapiens

<400>  1999
ggctcgggag agaccttgga gcgcgcggga aagagaccaa tataaactgt ggcgggatag       60

ttttcgggtc cttgtccagt gaaacaccct cggctgggaa gtcagttcgt tctctcctct      120

cctctcttct tgtttgaaca tggtgcggac taaagcagac agtgttccag gcacttacag      180

aaaagtggtg gctgctcgag cccccagaaa ggtgcttggt tcttccacct ctgccactaa      240

ttcgacatca gtttcatcga ggaaagagca tgtcctttgc aacctgatca cacaaatgat      300

gaaaaagaat agaactttct cattcatctt tgaataacgt ctccttgttt accctggtat      360

tctagaatgt aaatttacat aaatgtgttt gttccaatta gctttgttga acaggcattt      420

aattaaaaaa tttaggttta aatttagatg ttcaaaagta gttgtgaaat ttgagaattt      480

gtaagactaa ttatggtaac ttagcttagt attcaatata atgcattgtt tggtttcttt      540

taccaaatta agtgtctagt tcttgctaaa atcaagtcat tgcattgtgt tctaattaca      600

agtatgttgt atttgagatt tgcttagatt gttgtactgc tgccattttt attggtgttt      660

gattattgga atggtgccat attgtcactc cttctacttg ctttaaaaag cagagttaga      720

tttttgcaca ttaaaaaatt cagtattaat taaacattac ttattctacc ctcttttttg      780

gcaaggagga caaatacgca atgttggaaa accttggatg gatatcttct ctttaaaaaa      840

atgtaaagat aatttggtct tgagggttta aacggttgat aatgcctcta caacaacaag      900

aaaaaagata aaatactagg atagaatcat ggtgggcaca gtggcttctc aggaggctga      960

ggagggaggt ttgcttgagt ccaggagttg gagaccagcc caggcaacat agcgtaaacc     1020

ctatctctaa aacaattttt agccgggtgc ggtggctcac gcctgtaatc ccagcactct     1080

gggaggccga ggcgggtgga tcatgaggtc aggagatcga gaccatcctg cctaacaagg     1140

tgaaaccccg tctctactaa aaatacaaaa aattagccgg gcgcggtggc gggcgcctgt     1200

agtcccagct actcgggagg ctgaggcagg agaatggcgt gaacccggga agtggagctt     1260

gcagtgagcc gagattgcgc cactgcagtc ggcagtccgg cttgggcgac agagcgagac     1320

tccgtctcaa aaaaaaaaaa aaaaaaaaaa aa                                   1352


<210>  2000
<211>  1515
<212>  DNA
<213>  homo sapiens

<400>  2000
ggctcgggag agaccttgga gcgcgcggga aagagaccaa tataaactgt ggcgggatag       60

ttttcgggtc cttgtccagt gaaacaccct cggctgggaa gtcagttcgt tctctcctct      120

cctctcttct tgtttgaaca tggtgcggac taaagcagac agtgttccag gcacttacag      180

aaaagtggtg gctgctcgag cccccagaaa ggtgcttggt tcttccacct ctgccactaa      240

ttcgacatca gtttcatcga ggaaagctga aaataaatat gcaggaggga accccgtttg      300

cgtgcgccca actcccaagt ggcaaaaagg aattggagaa ttctttaggt tgtcccctaa      360

agattctgaa aaagagaatc agattcctga agaggcagga agcagtggct taggaaaagc      420

aaagagaaaa gcatgtcctt tgcaacctga tcacacaaat gatgaaaaag aatagaactt      480

tctcattcat ctttgaataa cgtctccttg tttaccctgg tattctagaa tgtaaattta      540

cataaatgtg tttgttccaa ttagctttgt tgaacaggca tttaattaaa aaatttaggt      600

ttaaatttag atgttcaaaa gtagttgtga aatttgagaa tttgtaagac taattatggt      660

aacttagctt agtattcaat ataatgcatt gtttggtttc ttttaccaaa ttaagtgtct      720

agttcttgct aaaatcaagt cattgcattg tgttctaatt acaagtatgt tgtatttgag      780

atttgcttag attgttgtac tgctgccatt tttattggtg tttgattatt ggaatggtgc      840

catattgtca ctccttctac ttgctttaaa aagcagagtt agatttttgc acattaaaaa      900

attcagtatt aattaaacat tacttattct accctctttt ttggcaagga ggacaaatac      960

gcaatgttgg aaaaccttgg atggatatct tctctttaaa aaaatgtaaa gataatttgg     1020

tcttgagggt ttaaacggtt gataatgcct ctacaacaac aagaaaaaag ataaaatact     1080

aggatagaat catggtgggc acagtggctt ctcaggaggc tgaggaggga ggtttgcttg     1140

agtccaggag ttggagacca gcccaggcaa catagcgtaa accctatctc taaaacaatt     1200

tttagccggg tgcggtggct cacgcctgta atcccagcac tctgggaggc cgaggcgggt     1260

ggatcatgag gtcaggagat cgagaccatc ctgcctaaca aggtgaaacc ccgtctctac     1320

taaaaataca aaaaattagc cgggcgcggt ggcgggcgcc tgtagtccca gctactcggg     1380

aggctgaggc aggagaatgg cgtgaacccg ggaagtggag cttgcagtga gccgagattg     1440

cgccactgca gtcggcagtc cggcttgggc gacagagcga gactccgtct caaaaaaaaa     1500

aaaaaaaaaa aaaaa                                                      1515


<210>  2001
<211>  2632
<212>  DNA
<213>  homo sapiens

<400>  2001
aaagcagtcc tgcacttcca gttgtgagcc aagagccaag tgtgggagct caccatggtg       60

gcagccacct ccccaccaag caggcagcgt tcaccagagg ggagtatcag gttcctgtac      120

tcagctgtgg gttgtcactg tctaataata tgaccgtttt gccatctctc tgcaaatgag      180

gctgaagctg ctatctgatt ggtataacat ctcactttcc ctctgcattg attttcttct      240

tctcctcctt tgcttcataa aaagagggac aagtggctgg tgctgtggac agagaagctt      300

tatttttagt atgagacaac ctctattttc tttcaggaga gggaagttgg attatcaatt      360

cttttgtaaa tgtgtatggt gatatttgct ccgctttttg caatctttgc atttgcaaca      420

tgcggtggct attctggagg cctgcggctg agtgtggact gcgtcaacaa gacagaaagt      480

aacctcagca tcgacatagc gtttgcctac ccattcaggt tgcaccaggt gacgtttgag      540

gtgcccacct gcgagggaaa ggaacggcag aagctggcat tgattggtga ctcctcgtct      600

tcagcagagt tcttcgtcac tgttgctgtc ttcgccttcc tctactcttt ggctgccact      660

gtcgtttaca ttttcttcca gaacaaatac cgggaaaaca accggggccc actcattgac      720

ttcattgtca ctgtagtctt ttcgttcttg tggttggtgg gttcatcagc ttgggcaaaa      780

ggactgtctg acgtcaaagt tgcaacggat cccaaggaag tattgctact aatgtcagct      840

tgcaaacagc catccaacaa atgcatggct atccacagcc ctgttatgtc aagcttaaac      900

acttctgtgg tctttggatt cttgaacttt attctctggg ctggaaacat atggtttgtt      960

ttcaaggaga ccggctggca ttcttcggga cagagatatc tttcagatcc aatggagaag     1020

cactccagca gctataatca aggtggttac aaccaagaca gctatggatc aagcagtggg     1080

tacagtcagc aggcgagttt ggggccaacc tcagatgagt ttggccaaca gcctactggc     1140

cccacttcct ttaccaatca gatttaacag agtagcattt gcattcttct gcagtcgcct     1200

caccatcttc catttcagtg gcagaagaat tttttaaggg tttcaatcaa ttattaatgc     1260

agagagtatt gaatgtaaat cagagctctc tagtcttcat taaggcagca agtcctgggt     1320

tgtgaaaaat gatacttaga gatgaggcga catgaggaga tatattattc atcatagatg     1380

gctaattgga gagtaccttg ttatatatac agatactttc atggtcattt tgtatgtatg     1440

ttaaagtagt agaagtattt tgtagcttaa agtctctagt atgtaatatg cataaagtaa     1500

atcaaatagc gttgagtttt cttatgcatt ttgatgtgaa agatgttata ataatttcta     1560

gaagacaatt tggtgtatca caacatgcat gtcttatttt tttttagttt taagtcctat     1620

aggactatga gtctctaagt tatttgtttc agaaaattat tcttttttta tgtgataaat     1680

catatgattt aagtgcatga ataagcattt tcccacacaa tgaacatttg aactgtgttt     1740

atgaaaattt tctggtttgc accatgaatt tgtcaaatgg atatttatag gaatatattc     1800

actactttgt atactttgca aatttgtctc tctggcttta cccaagttct gaatgcattg     1860

taattaaaat ttaagttttt cttttccccc attagtaaac atttagtgct acatatgata     1920

actgcccaat atttattcta tttacttagc taaatatttg cattcttgta accttctatg     1980

gtgttttgtg gctcttatct tgtggaccat aaataacacg gcccaataac tctttgtgtt     2040

tatggagtgt tgttttctta gaataatgga gatgcagata tagataccat agtcaaggta     2100

ccgccttgct gaagtattta tttataaaga atattctgta gaacctctac taccagctat     2160

atttttaaat cctgtttatt tgtaaagcta atatgctcct caatgtaatt attaaaaatt     2220

ctcaagtcac agctaaactt actaattctg attttagtgt agcccctaaa ttaaaaatgg     2280

cttccatatg ccactctgta ccccaaagag agttctcatg aaatattctc cagaatgtat     2340

tcattatcaa gaaaatgtca atcgtcactt cctcgtttta actcagctga aacaccagga     2400

cccaatagag agggcaagct gagcatctgt atttccagat aaaagttgtt attgatgtat     2460

aaactcgttg cgtgattagt gatgttggaa gcattttagc acaaaacagc cttgtgtctt     2520

agatgatatc tgtaaccagt ttctgaatcc cgttggataa aactgtattg tgatatctat     2580

ttgatgttaa taaagttatt gcatacaaaa aaaaaaaaaa aaaaaaaaaa aa             2632


<210>  2002
<211>  1539
<212>  DNA
<213>  homo sapiens

<400>  2002
cggccgcgag tcctgcgtga tcgcgagcat gtgtgcgtgc gcgtgtttat ctgaggcgcg       60

tgcggcggcc accccagcct agtcctcttc ttggtgccac tggctaacta ggttgagaaa      120

ccggcgccac aggcggcaca cctggcccgg agctggcccg ctcctccccg ccgagccggc      180

gccccaacaa cgcgccctct cccagtcctc acaaaggggc ctagtccggc ccccggctct      240

ggccgtgagg gagcgctgtg ggggcgcgct gccttctgcc tggaagtgtt gggcaggtgg      300

tgggagagcg tcaggcttga acaacatgat tttaaagcac gtgtctgtct gtcgtttttt      360

acttttaggg ttttggccaa attgggcgag ggcacaaaat aaccacttac cccttctcac      420

cgaggaagag cgggagaaag ggtatggcac agtcacaagg gtgggtgaaa agatacatca      480

aggccttttg taaaggcttc tttgtggcgg tgcctgtggc agtgactttc ttggatcggg      540

tcgcctgtgt ggcaagagta gaaggagcat cgatgcagcc ttctttgaat cctgggggga      600

gccagtcatc tgatgtggtg cttttgaacc actggaaagt gaggaatttt gaagtacacc      660

gtggtgacat tgtatcattg gtgtctccta aaaacccaga acagaagatc attaagagag      720

tgattgctct tgaaggagat attgtcagaa ccataggaca caaaaaccgg tatgtcaaag      780

tcccccgtgg tcacatctgg gttgaaggtg atcatcatgg acacagtttt gacagtaatt      840

cttttgggcc ggtttcccta ggacttctgc atgcccatgc cacacatatc ctgtggcccc      900

cagagcgctg gcagaaattg gaatctgttc ttcctccaga gcgcttacca gtacagagag      960

aagaggaatg actgcatgaa tctacctgag ttgctggcat tgggaggcca gttactggaa     1020

aggaatggaa aaaagaagcc tccaaaaggg aaaaacttct gacaatatga tgctgtgcga     1080

gaaatattta cagcacatta aaacgatctg tattattaaa taaataattt tcaaatgtta     1140

aacagtatta aatggcacct gattttgtgt taaattttag ttccctgttg tttaatgccc     1200

ccaaaatatg cagacctttg ggaatataaa aatattgcac ccacatgtct taatggggct     1260

gaatttcaga ttatttgtta catatactta ttatattgat tgttgggttt tgattttggt     1320

gcttgctgct gaaataaatt gaaaattaat attcaataaa aatgatgtat ttgtcacttg     1380

ctgttaaggt agaacaagaa ggaacacata ttatacacat aatgatggga attacattgt     1440

gatttgtact atctacaaag gagtaactgc cagttaggaa gaacagtaaa cagtgatgtt     1500

aaaataaaac aatgatttgc taaaaaaaaa aaaaaaaaa                            1539


<210>  2003
<211>  1539
<212>  DNA
<213>  homo sapiens

<400>  2003
cggccgcgag tcctgcgtga tcgcgagcat gtgtgcgtgc gcgtgtttat ctgaggcgcg       60

tgcggcggcc accccagcct agtcctcttc ttggtgccac tggctaacta ggttgagaaa      120

ccggcgccac aggcggcaca cctggcccgg agctggcccg ctcctccccg ccgagccggc      180

gccccaacaa cgcgccctct cccagtcctc acaaaggggc ctagtccggc ccccggctct      240

ggccgtgagg gagcgctgtg ggggcgcgct gccttctgcc tggaagtgtt gggcaggtgg      300

tgggagagcg tcaggcttga acaacatgat tttaaagcac gtgtctgtct gtcgtttttt      360

acttttaggg ttttggccaa attgggcgag ggcacaaaat aaccacttac cccttctcac      420

cgaggaagag cgggagaaag ggtatggcac agtcacaagg gtgggtgaaa agatacatca      480

aggccttttg taaaggcttc tttgtggcgg tgcctgtggc agtgactttc ttggatcggg      540

tcgcctgtgt ggcaagagta gaaggagcat cgatgcagcc ttctttgaat cctgggggga      600

gccagtcatc tgatgtggtg cttttgaacc actggaaagt gaggaatttt gaagtacacc      660

gtggtgacat tgtatcattg gtgtctccta aaaacccaga acagaagatc attaagagag      720

tgattgctct tgaaggagat attgtcagaa ccataggaca caaaaaccgg tatgtcaaag      780

tcccccgtgg tcacatctgg gttgaaggtg atcatcatgg acacagtttt gacagtaatt      840

cttttgggcc ggtttcccta ggacttctgc atgcccatgc cacacatatc ctgtggcccc      900

cagagcgctg gcagaaattg gaatctgttc ttcctccaga gcgcttacca gtacagagag      960

aagaggaatg actgcatgaa tctacctgag ttgctggcat tgggaggcca gttactggaa     1020

aggaatggaa aaaagaagcc tccaaaaggg aaaaacttct gacaatatga tgctgtgcga     1080

gaaatattta cagcacatta aaacgatctg tattattaaa taaataattt tcaaatgtta     1140

aacagtatta aatggcacct gattttgtgt taaattttag ttccctgttg tttaatgccc     1200

ccaaaatatg cagacctttg ggaatataaa aatattgcac ccacatgtct taatggggct     1260

gaatttcaga ttatttgtta catatactta ttatattgat tgttgggttt tgattttggt     1320

gcttgctgct gaaataaatt gaaaattaat attcaataaa aatgatgtat ttgtcacttg     1380

ctgttaaggt agaacaagaa ggaacacata ttatacacat aatgatggga attacattgt     1440

gatttgtact atctacaaag gagtaactgc cagttaggaa gaacagtaaa cagtgatgtt     1500

aaaataaaac aatgatttgc taaaaaaaaa aaaaaaaaa                            1539


<210>  2004
<211>  3245
<212>  DNA
<213>  homo sapiens

<400>  2004
cttctgtagc tcgcgttgaa gccgcacgtc cggccccgat cccggcacca tgagcttcgg       60

ctcggagcac tacctgtgct cctcctcctc ctaccgcaag gtgttcgggg atggctctcg      120

cctgtccgcc cgcctctctg gggccggcgg cgcgggcggc ttccgctcgc agtcgctgtc      180

ccgcagcaat gtggcctcct cggccgcctg ctcctcggcc tcgtcgctcg gcctcggcct      240

ggcctatcgc cggccgccgg cgtccgacgg gctggacctg agccaggcgg cggcgcgcac      300

caacgagtac aagatcatcc gcaccaacga gaaggagcag ctgcagggcc tcaacgaccg      360

cttcgccgtg ttcatcgaga aggtgcatca gctggagacg cagaaccgcg cgttggaggc      420

cgagctggcc gcgctgcgac agcgccacgc tgagccgtcg cgcgtcggcg agctcttcca      480

gcgcgagctg cgcgacctgc gcgcgcagct ggaggaggcc agctcggctc gctcgcaggc      540

cctgctggag cgcgacgggc tggcggagga ggtgcagcgg ctgcgggcgc gctgcgagga      600

ggagagccgc ggacgcgaag gcgccgagcg cgccctgaag gcgcagcagc gcgacgtgga      660

cggcgccacg ctggcccgcc tggacctgga gaagaaggtg gagtcgctgc tggacgagct      720

ggccttcgta cgccaggtgc acgacgagga ggtagccgag ctgctggcca cgctgcaggc      780

gtcgtcgcag gccgcggccg aggtggacgt gactgtggct aaaccagacc tgacctcggc      840

tctgagggag atccgcgccc agtatgagtc cctggccgct aagaacctgc agtccgcgga      900

agaatggtac aagtccaagt ttgccaacct gaacgagcag gcggcgcgca gcaccgaggc      960

catccgggcc agccgcgagg agatccacga gtatcggcgc cagctgcagg cgcgcaccat     1020

cgagatcgag ggcctgcgcg gggccaacga gtccttggag aggcagatcc tggagctgga     1080

ggagcggcac agtgccgagg tagctggcta ccaggatagc attgggcagc tggagaatga     1140

tctgaggaac accaagagtg agatggcacg ccaccttcgg gaataccagg acttgctcaa     1200

tgtcaaaatg gctcttgaca ttgagatagc agcttacagg aaactgctgg aaggcgagga     1260

gacacgtttt agcaccagtg ggttaagcat ttcggggctg aatccacttc ccaatccaag     1320

ttacctgctc ccacctagaa tcctcagtgc tacaacctcc aaagtctcat ccactgggct     1380

atcacttaag aaagaggagg aggaggagga ggcatctaag gtagcctcta agaaaacctc     1440

ccagataggg gaaagttttg aagaaatatt agaggagaca gtaatatcta ctaagaaaac     1500

cgagaaatca aatatagaag aaaccaccat ttcaagccaa aaaatataat tccattgctt     1560

tgaaaaagtt aatgcttaag agggaatgat atgcatttga cttgttaaac agcctattcc     1620

tgaactataa cacctgccac cactataaaa tgtcttcaag gcttcagtct catatttagt     1680

attgaatact tacattctct aataagaaaa ccacccctta gattgaagta aactgcagtc     1740

ctggagcaat cacagatgag ttatctaaga atacagcttt ctgaccttca gctcacgctt     1800

cacagtgatc gatgattcag gtgcagagga agtacaaact aaggtgctaa atctgcgatc     1860

atcgtcattt gctgtgaact gaaattaaaa ctattcatgc tacccagcca ttacccagct     1920

aaataatctt actctagata cctaaaacat aagatcactg ccagagataa actaatggtc     1980

cacacccaat tccactctga tagaattatt tcacaaataa taggtgtttg tttaatggac     2040

acttttcacc tccttcaatt ccatatatcc ttttcttcta tgtaggaaaa aaatagtcta     2100

gtgtagtatt cttccctttt aaacacattt tggttcttct caaaagaact tacccccatt     2160

cgcgctctgc tcagtgggta aaattagatg catgttgacc atgtctatga ttcgtgtaat     2220

tacttatccc tgcccatttc atattctttc aattctgtag gttaaaaaaa tggcagtgat     2280

gaattttaag ggtttccccc aacatataaa ataatgcaaa gaatccctag actttaggct     2340

ttcagcttac acaaatctat ttaattagga aaaaaactat taaggatgta gcttttcacc     2400

tttactttag aagcacagta aatatcccaa actgtgatga agccgacctt agatttagta     2460

gtgtaagcta gaagaagtga gtgtttctat gagtggaaaa agccaaggtg tcatttatgt     2520

gtcagttcat ttgtggtgat atagaattag ctttttcatc cccttaccct tagaatccac     2580

gtattcccct tcccactagc ctaggtcata aagaggcgtt gctttcactc tcctatgcct     2640

tttacgagtg ctaagtgtag gatattttgt caccagaaca caatgctacc gccccaaagt     2700

aaaagaaacc acttctggtc aatcaacact accagcgtat atataagaaa gacatctttc     2760

tcttttctaa aagacttccc taacacttac cccatggctg cacagttggt ggggtcctgc     2820

cggagaggaa gagacactca gaccagagaa ggggtgtgca tgcgcctact cgcttgctag     2880

aagtagattc tggacagtca gctcttcatc tgcccaactg tgtagcatct gcattgccca     2940

gtctttcatg tgtgccaagg ctgatgcagg atttgttctc tgtccagcag tcacttcggc     3000

cagagctgaa gagttgcccc gtctctgttc catgtctcct ttaagagctc tggtgataag     3060

gacatgatgc ttttactgaa ctttcttatc ctagcacatg cttcaatagt tcaaggaact     3120

tgaaaaatac ttttccttac ctttacccca tccctgtctt tactcctcac acttactgta     3180

agacattagt aacataataa attaaaagtc acacgaatct caccaacata aaaaaaaaaa     3240

aaaaa                                                                 3245


<210>  2005
<211>  3245
<212>  DNA
<213>  homo sapiens

<400>  2005
cttctgtagc tcgcgttgaa gccgcacgtc cggccccgat cccggcacca tgagcttcgg       60

ctcggagcac tacctgtgct cctcctcctc ctaccgcaag gtgttcgggg atggctctcg      120

cctgtccgcc cgcctctctg gggccggcgg cgcgggcggc ttccgctcgc agtcgctgtc      180

ccgcagcaat gtggcctcct cggccgcctg ctcctcggcc tcgtcgctcg gcctcggcct      240

ggcctatcgc cggccgccgg cgtccgacgg gctggacctg agccaggcgg cggcgcgcac      300

caacgagtac aagatcatcc gcaccaacga gaaggagcag ctgcagggcc tcaacgaccg      360

cttcgccgtg ttcatcgaga aggtgcatca gctggagacg cagaaccgcg cgttggaggc      420

cgagctggcc gcgctgcgac agcgccacgc tgagccgtcg cgcgtcggcg agctcttcca      480

gcgcgagctg cgcgacctgc gcgcgcagct ggaggaggcc agctcggctc gctcgcaggc      540

cctgctggag cgcgacgggc tggcggagga ggtgcagcgg ctgcgggcgc gctgcgagga      600

ggagagccgc ggacgcgaag gcgccgagcg cgccctgaag gcgcagcagc gcgacgtgga      660

cggcgccacg ctggcccgcc tggacctgga gaagaaggtg gagtcgctgc tggacgagct      720

ggccttcgta cgccaggtgc acgacgagga ggtagccgag ctgctggcca cgctgcaggc      780

gtcgtcgcag gccgcggccg aggtggacgt gactgtggct aaaccagacc tgacctcggc      840

tctgagggag atccgcgccc agtatgagtc cctggccgct aagaacctgc agtccgcgga      900

agaatggtac aagtccaagt ttgccaacct gaacgagcag gcggcgcgca gcaccgaggc      960

catccgggcc agccgcgagg agatccacga gtatcggcgc cagctgcagg cgcgcaccat     1020

cgagatcgag ggcctgcgcg gggccaacga gtccttggag aggcagatcc tggagctgga     1080

ggagcggcac agtgccgagg tagctggcta ccaggatagc attgggcagc tggagaatga     1140

tctgaggaac accaagagtg agatggcacg ccaccttcgg gaataccagg acttgctcaa     1200

tgtcaaaatg gctcttgaca ttgagatagc agcttacagg aaactgctgg aaggcgagga     1260

gacacgtttt agcaccagtg ggttaagcat ttcggggctg aatccacttc ccaatccaag     1320

ttacctgctc ccacctagaa tcctcagtgc tacaacctcc aaagtctcat ccactgggct     1380

atcacttaag aaagaggagg aggaggagga ggcatctaag gtagcctcta agaaaacctc     1440

ccagataggg gaaagttttg aagaaatatt agaggagaca gtaatatcta ctaagaaaac     1500

cgagaaatca aatatagaag aaaccaccat ttcaagccaa aaaatataat tccattgctt     1560

tgaaaaagtt aatgcttaag agggaatgat atgcatttga cttgttaaac agcctattcc     1620

tgaactataa cacctgccac cactataaaa tgtcttcaag gcttcagtct catatttagt     1680

attgaatact tacattctct aataagaaaa ccacccctta gattgaagta aactgcagtc     1740

ctggagcaat cacagatgag ttatctaaga atacagcttt ctgaccttca gctcacgctt     1800

cacagtgatc gatgattcag gtgcagagga agtacaaact aaggtgctaa atctgcgatc     1860

atcgtcattt gctgtgaact gaaattaaaa ctattcatgc tacccagcca ttacccagct     1920

aaataatctt actctagata cctaaaacat aagatcactg ccagagataa actaatggtc     1980

cacacccaat tccactctga tagaattatt tcacaaataa taggtgtttg tttaatggac     2040

acttttcacc tccttcaatt ccatatatcc ttttcttcta tgtaggaaaa aaatagtcta     2100

gtgtagtatt cttccctttt aaacacattt tggttcttct caaaagaact tacccccatt     2160

cgcgctctgc tcagtgggta aaattagatg catgttgacc atgtctatga ttcgtgtaat     2220

tacttatccc tgcccatttc atattctttc aattctgtag gttaaaaaaa tggcagtgat     2280

gaattttaag ggtttccccc aacatataaa ataatgcaaa gaatccctag actttaggct     2340

ttcagcttac acaaatctat ttaattagga aaaaaactat taaggatgta gcttttcacc     2400

tttactttag aagcacagta aatatcccaa actgtgatga agccgacctt agatttagta     2460

gtgtaagcta gaagaagtga gtgtttctat gagtggaaaa agccaaggtg tcatttatgt     2520

gtcagttcat ttgtggtgat atagaattag ctttttcatc cccttaccct tagaatccac     2580

gtattcccct tcccactagc ctaggtcata aagaggcgtt gctttcactc tcctatgcct     2640

tttacgagtg ctaagtgtag gatattttgt caccagaaca caatgctacc gccccaaagt     2700

aaaagaaacc acttctggtc aatcaacact accagcgtat atataagaaa gacatctttc     2760

tcttttctaa aagacttccc taacacttac cccatggctg cacagttggt ggggtcctgc     2820

cggagaggaa gagacactca gaccagagaa ggggtgtgca tgcgcctact cgcttgctag     2880

aagtagattc tggacagtca gctcttcatc tgcccaactg tgtagcatct gcattgccca     2940

gtctttcatg tgtgccaagg ctgatgcagg atttgttctc tgtccagcag tcacttcggc     3000

cagagctgaa gagttgcccc gtctctgttc catgtctcct ttaagagctc tggtgataag     3060

gacatgatgc ttttactgaa ctttcttatc ctagcacatg cttcaatagt tcaaggaact     3120

tgaaaaatac ttttccttac ctttacccca tccctgtctt tactcctcac acttactgta     3180

agacattagt aacataataa attaaaagtc acacgaatct caccaacata aaaaaaaaaa     3240

aaaaa                                                                 3245


<210>  2006
<211>  3702
<212>  DNA
<213>  homo sapiens

<400>  2006
agtggggggg aaggttctag aaaagcggcg gcagcggctc tagcggcagt agcagcagcg       60

ccgggtcccg tgcggaggtg ctcctcgcag agttgtttct cgagcagcgg cagttctcac      120

tacagcgcca ggacgagtcc ggttcgtgtt cgtccgcgga gatctctctc atctcgctcg      180

gctgcgggaa atcgggctga agcgactgag tccgcgatgg agaaaacttt agaaactgtt      240

cctttggaga ggaaaaagag agaaaaggaa cagttccgta agctctttat tggtggctta      300

agctttgaaa ccacagaaga aagtttgagg aactactacg aacaatgggg aaagcttaca      360

gactgtgtgg taatgaggga tcctgcaagc aaaagatcaa gaggatttgg ttttgtaact      420

ttttcatcca tggctgaggt tgatgctgcc atggctgcaa gacctcattc aattgatggg      480

agagtagttg agccaaaacg tgctgtagca agagaggaat ctggaaaacc aggggctcat      540

gtaactgtga agaagctgtt tgttggcgga attaaagaag atactgagga acatcacctt      600

agagattact ttgaggaata tggaaaaatt gataccattg agataattac tgataggcag      660

tctggaaaga aaagaggctt tggctttgtt acttttgatg accatgatcc tgtggataaa      720

atcgtattgc agaaatacca taccatcaat ggtcataatg cagaagtaag aaaggctttg      780

tctagacaag aaatgcagga agttcagagt tctaggagtg gaagaggagg caactttggc      840

tttggggatt cacgtggtgg cggtggaaat ttcggaccag gaccaggaag taactttaga      900

ggaggatctg atggatatgg cagtggacgt ggatttgggg atggctataa tgggtatgga      960

ggaggacctg gaggtggcaa ttttggaggt agccccggtt atggaggagg aagaggagga     1020

tatggtggtg gaggacctgg atatggcaac cagggtgggg gctacggagg tggttatgac     1080

aactatggag gaggaaatta tggaagtgga aattacaatg attttggaaa ttataaccag     1140

caaccttcta actacggtcc aatgaagagt ggaaactttg gtggtagcag gaacatgggg     1200

ggaccatatg gtggaggaaa ctatggtcca ggaggcagtg gaggaagtgg gggttatggt     1260

gggaggagcc gatactgagc ttcttcctat ttgccatggg cttcactgta taaataggag     1320

aggatgagag cccagaggta acagaacagc ttcaggttat cgaaataaca atgttaagga     1380

aactcttatc tcagtcatgc ataaatatgc agtgatatgg cagaagacac cagagcagat     1440

gcagagagcc attttgtgaa tggattggat tatttaataa cattacctta ctgtggagga     1500

aggattgtaa aaaaaaatgc ctttgagaca gtttcttagc tttttaattg ttgtttcttt     1560

ctagtggtct ttgtaagagt gtagaagcat tccttctttg ataatgttaa atttgtaagt     1620

ttcaggtgac atgtgaaacc ttttttaaga tttttctcaa agttttgaaa agctattagc     1680

caggatcatg gtgtaataag acataacgtt tttcctttaa aaaaatttaa gtgcgtgtgt     1740

agagttaaga agctgttgta catttatgat ttaataaaat aattctaaag gaaattgtgt     1800

aattatagac tttttatttt aaataagtta aggagtgggt agtataatta aggtccgttg     1860

caaagctgtt gttatatttg tataagataa atgctggtca gatgtaagtg tgttgtctgc     1920

aattcatcag gattaaatta tgtagataac ttaagggata tctctgcaag gagaaacacc     1980

tttttagatc ttttagatgc tgcttcttca atgcaaggaa aggaaataac cccagcgagg     2040

tactcttcag ggacacaggt ctagtacaag agaactcttg acggctacta agttcagcca     2100

gtcttaaaaa actgtgctgt ttctacaaaa ctttaactac agtagtttat aaggatgcca     2160

acgaaagctg agggtgtaga gcaaaatagt tctaagcttc agttaaactt ctttaggtaa     2220

gatcttattt acttttcctt tcttaatttt cctccctaaa agataaacta atactcttaa     2280

atggtctttc agtatagtgg ttcttacgta gtttaacata gctataaatt gagtttaaca     2340

atttataaac tcaagagaat aatttttata aaccctgttt tccaatctgt catttactta     2400

aattattttg gttgtttttc cctttttttc cttcttttcc caccccctcc ccctccatgt     2460

gaagatttgg gtgcttaaca tatcattttt ttccctgccg gaattttagc attgatatga     2520

accatggaca agtatattct gctgccacaa agactgtaaa gtgcttcatt tcaacagctg     2580

aggcaagcca agtgatcatt aataaagctt ttcttggttc cttcagtggt gttggtagta     2640

aaatggtagg taaaagttag gctgcaagtt caataaatca tgagatttcc catcgttaca     2700

cccttgtgta ttcacatttc ttggatcaaa cattttgagt gaactagggg tttttattaa     2760

agacatttgt tgtatttatg gttgtaactg tacatgctta tcaggatgag actgaaagaa     2820

ggtagggcaa aaatggttga atctattttc agatagtagt tcatacttga gtgaagtgtc     2880

ttgtctgcat tatgaagcct ggtatgtatc cagtactaaa taggtgggtt aaatgtggta     2940

attctagttc agtgtcttac cctgaagaga aagttgtagg ttggctgttg aaattcattc     3000

cttagatatg atcagtttga ttgcccggct ttattgcctt tacaggaatg tgatactcag     3060

ggcttactct atacaccaat gagtcttctt tgatcctaag accaccactg aagttgttta     3120

ggttcttttg gacaaacatg ataaacttct tcagatactt tttttttcct ttggcaggaa     3180

ggtgtcttgc tgcaggtaac taatgaagaa gtggtcaacc acagagtctt caagaaataa     3240

gaaattctgt accatctgaa agtagttctt gttggtgcct tcatttaaaa agcactcttt     3300

aaaataaaag ggaaatgttt tctgataaaa caaacattta gttgaggttc ttgatataaa     3360

acaattacaa aatgagtgtt gtttgtaaaa cagtaacatc aaattggcta gagagataaa     3420

tgtatcatgt tttaaattag gttttgtgag tagacagatt acaattctat tttaaatata     3480

aagtttataa aataaatact ttttgtatcc aaatacttgg tgtaatgttt acacataaaa     3540

tgtgtgaatc ttgttctata aatatttggt tgtctaaaag atcaccatcc cctaaatttt     3600

taaaagcagt ttcacaaagc tatgcatatt ttaatattaa caggtaaatg agaagagcat     3660

tgtggacatt attggctgtc cccaataaaa tgctgttcat ta                        3702


<210>  2007
<211>  3702
<212>  DNA
<213>  homo sapiens

<400>  2007
agtggggggg aaggttctag aaaagcggcg gcagcggctc tagcggcagt agcagcagcg       60

ccgggtcccg tgcggaggtg ctcctcgcag agttgtttct cgagcagcgg cagttctcac      120

tacagcgcca ggacgagtcc ggttcgtgtt cgtccgcgga gatctctctc atctcgctcg      180

gctgcgggaa atcgggctga agcgactgag tccgcgatgg agaaaacttt agaaactgtt      240

cctttggaga ggaaaaagag agaaaaggaa cagttccgta agctctttat tggtggctta      300

agctttgaaa ccacagaaga aagtttgagg aactactacg aacaatgggg aaagcttaca      360

gactgtgtgg taatgaggga tcctgcaagc aaaagatcaa gaggatttgg ttttgtaact      420

ttttcatcca tggctgaggt tgatgctgcc atggctgcaa gacctcattc aattgatggg      480

agagtagttg agccaaaacg tgctgtagca agagaggaat ctggaaaacc aggggctcat      540

gtaactgtga agaagctgtt tgttggcgga attaaagaag atactgagga acatcacctt      600

agagattact ttgaggaata tggaaaaatt gataccattg agataattac tgataggcag      660

tctggaaaga aaagaggctt tggctttgtt acttttgatg accatgatcc tgtggataaa      720

atcgtattgc agaaatacca taccatcaat ggtcataatg cagaagtaag aaaggctttg      780

tctagacaag aaatgcagga agttcagagt tctaggagtg gaagaggagg caactttggc      840

tttggggatt cacgtggtgg cggtggaaat ttcggaccag gaccaggaag taactttaga      900

ggaggatctg atggatatgg cagtggacgt ggatttgggg atggctataa tgggtatgga      960

ggaggacctg gaggtggcaa ttttggaggt agccccggtt atggaggagg aagaggagga     1020

tatggtggtg gaggacctgg atatggcaac cagggtgggg gctacggagg tggttatgac     1080

aactatggag gaggaaatta tggaagtgga aattacaatg attttggaaa ttataaccag     1140

caaccttcta actacggtcc aatgaagagt ggaaactttg gtggtagcag gaacatgggg     1200

ggaccatatg gtggaggaaa ctatggtcca ggaggcagtg gaggaagtgg gggttatggt     1260

gggaggagcc gatactgagc ttcttcctat ttgccatggg cttcactgta taaataggag     1320

aggatgagag cccagaggta acagaacagc ttcaggttat cgaaataaca atgttaagga     1380

aactcttatc tcagtcatgc ataaatatgc agtgatatgg cagaagacac cagagcagat     1440

gcagagagcc attttgtgaa tggattggat tatttaataa cattacctta ctgtggagga     1500

aggattgtaa aaaaaaatgc ctttgagaca gtttcttagc tttttaattg ttgtttcttt     1560

ctagtggtct ttgtaagagt gtagaagcat tccttctttg ataatgttaa atttgtaagt     1620

ttcaggtgac atgtgaaacc ttttttaaga tttttctcaa agttttgaaa agctattagc     1680

caggatcatg gtgtaataag acataacgtt tttcctttaa aaaaatttaa gtgcgtgtgt     1740

agagttaaga agctgttgta catttatgat ttaataaaat aattctaaag gaaattgtgt     1800

aattatagac tttttatttt aaataagtta aggagtgggt agtataatta aggtccgttg     1860

caaagctgtt gttatatttg tataagataa atgctggtca gatgtaagtg tgttgtctgc     1920

aattcatcag gattaaatta tgtagataac ttaagggata tctctgcaag gagaaacacc     1980

tttttagatc ttttagatgc tgcttcttca atgcaaggaa aggaaataac cccagcgagg     2040

tactcttcag ggacacaggt ctagtacaag agaactcttg acggctacta agttcagcca     2100

gtcttaaaaa actgtgctgt ttctacaaaa ctttaactac agtagtttat aaggatgcca     2160

acgaaagctg agggtgtaga gcaaaatagt tctaagcttc agttaaactt ctttaggtaa     2220

gatcttattt acttttcctt tcttaatttt cctccctaaa agataaacta atactcttaa     2280

atggtctttc agtatagtgg ttcttacgta gtttaacata gctataaatt gagtttaaca     2340

atttataaac tcaagagaat aatttttata aaccctgttt tccaatctgt catttactta     2400

aattattttg gttgtttttc cctttttttc cttcttttcc caccccctcc ccctccatgt     2460

gaagatttgg gtgcttaaca tatcattttt ttccctgccg gaattttagc attgatatga     2520

accatggaca agtatattct gctgccacaa agactgtaaa gtgcttcatt tcaacagctg     2580

aggcaagcca agtgatcatt aataaagctt ttcttggttc cttcagtggt gttggtagta     2640

aaatggtagg taaaagttag gctgcaagtt caataaatca tgagatttcc catcgttaca     2700

cccttgtgta ttcacatttc ttggatcaaa cattttgagt gaactagggg tttttattaa     2760

agacatttgt tgtatttatg gttgtaactg tacatgctta tcaggatgag actgaaagaa     2820

ggtagggcaa aaatggttga atctattttc agatagtagt tcatacttga gtgaagtgtc     2880

ttgtctgcat tatgaagcct ggtatgtatc cagtactaaa taggtgggtt aaatgtggta     2940

attctagttc agtgtcttac cctgaagaga aagttgtagg ttggctgttg aaattcattc     3000

cttagatatg atcagtttga ttgcccggct ttattgcctt tacaggaatg tgatactcag     3060

ggcttactct atacaccaat gagtcttctt tgatcctaag accaccactg aagttgttta     3120

ggttcttttg gacaaacatg ataaacttct tcagatactt tttttttcct ttggcaggaa     3180

ggtgtcttgc tgcaggtaac taatgaagaa gtggtcaacc acagagtctt caagaaataa     3240

gaaattctgt accatctgaa agtagttctt gttggtgcct tcatttaaaa agcactcttt     3300

aaaataaaag ggaaatgttt tctgataaaa caaacattta gttgaggttc ttgatataaa     3360

acaattacaa aatgagtgtt gtttgtaaaa cagtaacatc aaattggcta gagagataaa     3420

tgtatcatgt tttaaattag gttttgtgag tagacagatt acaattctat tttaaatata     3480

aagtttataa aataaatact ttttgtatcc aaatacttgg tgtaatgttt acacataaaa     3540

tgtgtgaatc ttgttctata aatatttggt tgtctaaaag atcaccatcc cctaaatttt     3600

taaaagcagt ttcacaaagc tatgcatatt ttaatattaa caggtaaatg agaagagcat     3660

tgtggacatt attggctgtc cccaataaaa tgctgttcat ta                        3702


<210>  2008
<211>  3625
<212>  DNA
<213>  homo sapiens

<400>  2008
ggcgggcgct cggcgactcg tccccggggc cccgcgcggg cccgggcagc aggggcgtga       60

tgtcacggca gggagggggc gcgggagccg ccgggccggc ggggaggcgg gggaggtgtt      120

ttccagcttt aaaaaggcag gaggcagagc gcggccctgc gtcagagcga gactcagagg      180

ctccgaactc gccggcggag tcgccgcgcc agatcccagc agcagggcgc gggcaccggg      240

gcgcgggcag ggctcggagc caccgcgcag gtcctagggc cgcggccggg ccccgccacg      300

cgcgcacacg cccctcgatg actttcctcc ggggcgcgcg gcgctgagcc cggggcgagg      360

gctgtcttcc cggagacccg accccggcag cgcggggcgg ccgcttctcc tgtgcctccg      420

cccgccgctc cactccccgc cgccgccgcg cggatgccaa gcaccagctt tccagtccct      480

tccaagtttc cacttggccc tgcggctgcg gtcttcggga gaggagaaac tttggggccc      540

gcgccgcgcg ccggcggcac catgaagtca gcggaggaag cccgaccctg cccgccctgg      600

actggcagct gccgtcccac tcaggcccgt atgagcttcg gattgaggtg cagcccaagt      660

cccaccaccg agcccactac gagacggagg gcagccgggg ggccgtgaag gcgtcggccg      720

gaggacaccc catcgtgcag ctgcatggct acttggagaa tgagccgctg atgctgcagc      780

ttttcattgg gacggcggac gaccgcctgc tgcgcccgca cgccttctac caggtgcacc      840

gcatcacagg gaagaccgtg tccaccacca gccacgaggc catcctctcc aacaccaaag      900

tcctggagat cccactcctg ccggagaaca gcatgcgagc cgtcattgac tgtgccggaa      960

tcctgaaact cagaaactcc gacattgaac ttcggaaagg agagacggac atcgggagga     1020

agaacacacg ggtacggctg gtgttccgcg ttcacgtccc gcaacccagc ggccgcacgc     1080

tgtccctgca ggtggcctcc aaccccatcg aatgctccca gcgctcagct caggagctgc     1140

ctctggtgga gaagcagagc acggacagct atccggtcgt gggcgggaag aagatggtcc     1200

tgtctggcca caacttcctg caggactcca aggtcatttt cgtggagaaa gccccagatg     1260

gccaccatgt ctgggagatg gaagcgaaaa ctgaccggga cctgtgcaag ccgaattctc     1320

tggtggttga gatcccgcca tttcggaatc agaggataac cagccccgtt cacgtcagtt     1380

tctacgtctg caacgggaag agaaagcgaa gccagtacca gcgtttcacc taccttcccg     1440

ccaacgttcc aattataaaa acagaaccca ctgatgatta tgagcctgct ccaacctgtg     1500

gaccggtgag ccaggggtta agtcctctcc caagaccata ctacagccag cagctcgcga     1560

tgccacccga ccccagctcc tgcctcgtgg ccggcttccc gccctgtccg cagagaagca     1620

ccctgatgcc agcggcccct ggcgtgagcc ccaagctcca cgacctttct cccgctgcct     1680

acaccaaggg cgttgccagc ccgggccact gtcacctcgg actcccgcag ccggccggag     1740

aggcccccgc cgtccaggac gtgcccaggc cagtggccac gcaccccggc tcgcccgggc     1800

agccaccccc ggccctgctg ccacagcagt aaatgaaata atacgaaatg acctctccag     1860

cacgagcacc cactcctagt tgccacattg gagcactcag ttcagcaggg gtatgctgac     1920

ttcagcagac aaagactttt gaataaataa actgaactca cacctggtac cactcagaac     1980

ctccaactga ctgaatgcca ggagctgaac attaatatgt gcaaagattg gctctccaac     2040

aagaaggaaa gcagggagga agggagacca ctgtgtcacc tggaggagaa gtcatctcat     2100

gacaacagaa gggaggtggc cgggctgagc acgggagacc caccgtgcag gggcctttca     2160

tgggaacggc ccacacgcag tttgacccca cgcccagccc ttctggcacc cctggggttc     2220

aatactggaa gtgccttatt taaccagacc atcagggcat catagaattg agcattgaat     2280

ttgctactgt aggagtattt ttaggagcag aaactgcaaa cacatttcat tgtgaggttt     2340

taccctctgt atgaatgaag agaacgctgg aaggctgcga gaggactcta gtatgagtct     2400

ccaacatttg gaacgtttcc tgggctgtca cgtacactcc tgctgcctta cacagtgcat     2460

tttagaatct tccagtctgt catctcagct cttttgtaac atgcttccct tgtctgcgcg     2520

gttgaaaccg taggcttgtt catagtcgca tgctcgcatc tttgttttta atctggcttc     2580

gaacatagca caagtaactt gaatagcaca tcaataggtt actggacaaa agcagaaaaa     2640

cctgttacag gatagcctgc atttgcatgt gtgtacatat ctaggcatct atttatgtat     2700

aaataataac agagccgacg tgtcctcgcc caggagggct tccctgtcag caataaccgg     2760

catccgtttt ggaacctgcg tctggggctc cagtcgctgc tcttgctggc gtccatcgcc     2820

gcctcggacg gccgtgcatt ttctcgtctc acgcagttcg aggaggaccc tagaaagcca     2880

ggagctgtga ttgacagtag ctgtaggtta ccagacggca acattagaaa gtgattgtaa     2940

ataacatgca acctaagtgt aatatatttg ttcagttata agatgattgt ttcacagaag     3000

ccttaccact ctctgcttca tctaagaaaa ccaataccaa aaacgccact ttaatgctca     3060

gccctgcgtt gtgtgttttc agatgagtta ctgttaacag gtaggtttgt gtaggccttg     3120

ctgggcactc tgtacaatta gttgcttatt acgtatgatt actcacagcg atctattgtt     3180

ccatataacc aaaaagcatg gtttattcat tgaaacacgg ttgacctgaa ctcgtgcctt     3240

aggaattaat gcccccttat ggaacctgcc tgaattgcac ctgcgggtgg aggctccggc     3300

tgtgaagtca ctgaacagaa cgtcgctgat ggagaaaggg ctcccgcaga aggaacggcc     3360

tgtaccgtgc gctccggcac aatcgcgtct cttgtgtctc actcacggaa agaaacaacc     3420

tgaaggccat cccgtcggtc tgcacgtaac cgtgaagacg tgtggccgcg tcccacctgc     3480

ggctgggtac cctgcacccg gcactgtagg agtcacgtgc agcctttctc aggggactgt     3540

cattgaaaag gaaacgtttg atgtctgtgt cagctgtctt tgtagttagg aaatagatcc     3600

aataaagccg tatttttttg ctgga                                           3625


<210>  2009
<211>  1799
<212>  DNA
<213>  homo sapiens

<400>  2009
ccgcccctca ccaacatggc cgcgggctgg aagtgcgcat gagcagctgt ctatggagat       60

acctaggccg ggagagggag aacacagttg gagaaaatcg gcagctgaga cggccttggc      120

cggacttagc actcaggcct gtgaatcagg agatacaaag acctccaaaa aaggaccagt      180

tcctcggatg tgccccctca cagagagatg aaggggcagc agaaaacagc tgaaacggaa      240

gaggggacag tgcagattca ggaaggtgca gtggctactg gggaagaccc aaccagtgtg      300

gctattgcca gcatccagtc agctgccacc ttccctgacc ccaacgtcaa gtgatgtaca      360

gggtgatcca ggtgtctgag gggcagctgg atggccaaac tgagggaact ggcgccatca      420

gtggctaccc tgccactcaa tccatgaccc aggcggtgat ccagggtgct ttcaccagtg      480

atgatgcagt tgacacggag gggacagctg ctgagacgca ctatacttac ttccccagca      540

cggcagtggg agatggggca gggggtacca catcggggag tacagctgct gttgttacta      600

cccagggctc agaggcactg ctggggcagg cgacccctcc tggcactggt caattctttg      660

tgatgatgtc accacaagaa gtactgcagg gaggaagcca gcgctcaatt gcccctagga      720

ctcaccctta ttccccgaag tcagaagctc cccggacgac tcgggatgag aaacgcaggg      780

ctcagcataa tgaagtggag cgtcgccgcc gagacaagat caacaactgg atcgtgcagc      840

tctccaagat aatcccagac tgctctatgg agagcaccaa gtctggccag agtaaaggtg      900

ggattctatc caaagcttgt gattatatcc aggagcttcg gcagagtaac caccgcttgt      960

ctgaagaact gcagggactt gaccaactgc agctggacaa tgacgtgctt cgacaacagg     1020

tggaagatct taaaaacaag aatctgctgc ttcgagctca gttgcggcac cacggattag     1080

aggtcgtcat caagaatgac agcaactaac tatggggatt caggggcttt gggcccaaga     1140

actgcagata gcccaggagc aacagcctaa tcccgtgccc ctttccttca ctgccccact     1200

tctggcatgg gacaggggga agttcagaag gtgtgtcctt gaactgaggc cctgtgatat     1260

ggcggcctgc agtggtgtga aacacacaat gtggacgtgc actgacagcc ttgcccaccc     1320

ccaccatgca gcccctgggc ccttgtgctc ctctcgcaca atgcatgtgc tgtctccatg     1380

ctggatactg gacacactaa actctggggc ttgtcctgtg cttgcttaga gtgcccagca     1440

gaggtttgct gacaggtgat gctctggctt gccccaggac tctggcactt ccattggttc     1500

ttcctttccc tggagctgag gtttagatgt gcaacctgtg gctcagggga gcaagcttac     1560

acaagaagtg agggaaggat gtttagcagt ggctggtgcc catgaagagg agattggcca     1620

gtgagaagct gaggcctatg cagacatctc tggagccaga gagaacaaca ggcaggggcc     1680

cacttggggc cttccccctt gtgggggtcg tttttttttt ttcttttctt tttttttttt     1740

tttttttttt ttttttaaga taaaattgtt caaagccaaa aaaaaaaaaa aaaaaaaaa      1799


<210>  2010
<211>  2904
<212>  DNA
<213>  homo sapiens

<400>  2010
gtgggcaaag gtacttaaag ccctgaccgt cgttctccgt cctcctctgg gtaccaactc       60

tattgcgcag ctcgctgccg tgcgtttaac ccaggcgagg aggaggagga gaaaattccc      120

ccagattcgg gcaggcccgc accccacatt ccgtcctgtt ttgagaggag gagggaagag      180

aaataaacgt ggcagcgcat agaaggccag cagggagact gctttccaga cacctccggc      240

ccacacagcc gttcaccccc cgtcttttca gtcctggaaa aggaattcgg tctgtcctta      300

ggatgaagct ctaactgaac tgaagtaagg agaaacagcc ttgaatcttt ggagggtctg      360

tcttcctttt gggctctgtg caactgcagc tacagtggaa aaaagcaaac tgctcttgat      420

cccaggccct gcctaagcct cagcagaact tgtaagccta aactgaagag cctcacccgg      480

acgagcaggc atcccttaac cttaagcaat ccagttccac gccctggatc agtgaataac      540

cccagctgca ccatgagccg cgttcgggat gctggctgtg tagcggcggg gatagtgata      600

ggggctggtg cctggtactg tgtctacaaa tacaccaggg ggagagacca gaccaagaag      660

agaatggcca agcccaaaaa ccgggctgtg gctgggactg gagccagggc tagagctggg      720

ctaagagccg gattcacaat cgaccttggg tcaggattca gtcccccaac cccagtccgt      780

gctgaagcag aggacagggc ccaggatgaa gcctctgctc tggacacagt tggagctgag      840

gcagtggccc cagctgcatc cagcgctgag gctcagagtg gggcaggcag tcaggcccaa      900

gaggcagatg gagccggggt tgggcctaag gccgaatcag tagttggggc tgcaatggct      960

tctgcaatag caccacctcc cggggtgaca gaggcccttg gggctgcaga agcccctgca     1020

atggcagggg ctcccaaagt ggcagaagct cccagagaag cggagacttc cagggcagcg     1080

gtgcctcctg ggacagtggt gcctaccgaa gcggcagcac ccactgaggt gaccgagggt     1140

cctggggtag cagcacctac caaggtagct gaagctcccg gggtggcatc gcctaccgag     1200

gcagctgagg ctcctgtgcc ggcaacgcct actggggctg cagcacctac tggggctgca     1260

gagtctcctg gaacttctgg ttcccctaga acagcggtgg ttcctggaac atcagctgcc     1320

aagaaagcaa cccctggggc tcacactggg gctataccga aagccacatc agcgactgga     1380

gcggtaccca aaggtggagg caagggtgta accaggtccc ggaatggggg caagggcaag     1440

ggcaagaaaa gcaaagttga agtagacgaa ctggggatgg gcttccgtcc tggagatggg     1500

gctgcagcag ctgctgcagc ctctgctaat ggcggacagg ctttcctggc agaggtccct     1560

gattctgagg aaggggagtc cgggtggact gacacagagt cagattcaga ctctgagccc     1620

gagacccagc gcagagggag gggaagaaga cccgttgcca tgcagaagcg cccctttcct     1680

tatgaaattg atgagattct gggtgtccgc gatctcagga aggtccttgc cttgcttcag     1740

aaatctgatg atcctttcat ccaacaggta gctttgctca ctctgagcaa caatgccaat     1800

tattcatgca atcaagagac aatccgcaaa ttgggaggcc tcccaattat tgcaaacatg     1860

atcaacaaaa ctgatccaca cattaaggaa aaagccttaa tggccatgaa taacctgagt     1920

gagaattatg aaaatcaggg ccggcttcag gtgtacatga ataaagtgat ggatgatatc     1980

atggcctcta acctgaactc agcagttcaa gtagttggac taaaatttct aacaaacatg     2040

actattacta atgactacca acacctgctt gtcaattcca ttgcaaactt tttccgtttg     2100

ctatctcagg gaggtggaaa aatcaaggtt gagattttga aaatcctttc gaattttgct     2160

gaaaatccag atatgttgaa gaaacttctc agtacccaag tgccagcatc atttagttcc     2220

ctctataatt cttacgtgga atcagaaatc cttattaatg cccttactct atttgagatt     2280

atctatgaca atctcagagc agaagtgttt aactatagag aattcaataa aggttccctt     2340

ttttacttat gcactacatc tggagtgtgt gttaagaaaa ttagagcctt agcaaatcac     2400

catgacctct tagtgaaagt gaaagttata aaactagtga acaaattctg attggttatg     2460

taccgtcaaa agacttgaag aaatttcatg attttgcagt gtggaagcgt tgaaaattga     2520

aagttactgc ttttccactt gctcatatag taaagggatc ctttcagctg ccagtgttga     2580

ataatgtatc atccagagtg atgttatctg tgacagtcac cagctttaag ctgaaccatt     2640

ttatgaatac caaataaata gacctcttgt actgaaaaca tatttgtgac tttaatcgtg     2700

ctgcttggat agaaatattt ttactggttc ttctgaattg acagtaaacc tgtccattat     2760

gaatggccta ctgttctatt atttgttttg acttgaattt atccaccaaa gacttcattt     2820

gtgtatcatc aataaagttg tatgtttcaa ctgacaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaa                                            2904


<210>  2011
<211>  4818
<212>  DNA
<213>  homo sapiens

<400>  2011
agcggggggg cgccccctgg cggcgcaggg accgccccca acctcgcgcc gccgccgccc       60

gcctcagccc aacatggcga tgcacaacaa ggcggcgccg ccgcagatcc cggacacccg      120

gcgggagctg gcggagctcg tgaagcggaa gcaggagctg gcggaaacat tggcaaattt      180

ggagcgacag atctatgctt ttgagggaag ctacctggaa gacactcaga tgtatggcaa      240

tattattcgt ggctgggatc ggtatctgac caaccaaaaa aactccaata gcaaaaatga      300

tcgaaggaac cggaagttta aggaagctga gcggctcttc agtaaatcct cggttacctc      360

agcagctgca gtaagtgcat tggcaggagt tcaggaccag ctcattgaaa agagggagcc      420

aggaagtggg acggaaagtg acacttctcc agacttccac aatcaggaaa atgagcccag      480

ccaggaggac cctgaggatc tggatggatc tgtgcaggga gtgaaacctc agaaggctgc      540

ttcttctact tcctcaggga gtcaccacag cagccataaa aagcgaaaga ataaaaaccg      600

gcacagcccg tctggcatgt ttgattatga ctttgagatt gatctgaagt taaacaaaaa      660

accacgagct gactattaga agacacatta gtgcagaagc ttccaggctg tagagccctg      720

cttcccttct ctgacctcac aaagataaac atccttcacc tgagttcgtg gccatccacc      780

tctgctctcc cagacccagt gcctgtgact ttgagtagtt tgttctaaat gtggtgacaa      840

acaagtcatt tctgtaagac attgggtctt actttatgtc atttttagta acagaactgc      900

aggaagatga agacaatgtt gtaatcccag caagttgcta actgtgcgtt tctcccttct      960

tagaatgaat gtctccccca aaactggctg gcaccagctt catctgtgat acccttcaag     1020

aaatgttctc tggttttgtt ttatgctgaa agtagaacac aagtcacatt tcagatggag     1080

gctgtaaata tctggcattt tcttatattg ttttatgttt tcttgttttt ctcttgttgt     1140

ttttatctta ttttctttgg ggtttttttg taatgccttt gtacagctca tactttcctg     1200

ctgacatatc tgatcatctc tttcatgcag ttgccaatat tcataactga aaataatctg     1260

gtttatcata agtaaaatgg gaaacttgcc tctgtttttt gcaaggggag gtaaagagtg     1320

tttagtaatt acctatctta aatctttctg agttggtagt agattcatgt tcaaggaaca     1380

ggaaaaatgg aaaaacataa gtttaaatca gttcttttta aataactttt tattcttttg     1440

tataaataaa atttcacagg cttcaaattc tcatgcttta cttttaaacc cgagattgtt     1500

ttttcactta tttattcata tcatgcctta tggaaatttc tttttctgta ttttctctct     1560

ttgctggtat tcacctgatt aaatattgct ctaaaaatca ccatggcata tggaaagtct     1620

caaaattata ccaaaagtga taacttatgt cgttcttaag tggagtgaaa ggatagcatc     1680

agtgagagcc agtgttgccc accaggtctc cctttcttgg agggcttgtt ggggctgagg     1740

aatctgctag taatcgttac ctgcctctag tgctgtggtg aacttgcgac agggtctggc     1800

tgcacattgg aatcacctga gaagctttaa aatactcatg cctggatccc atccctagag     1860

actggggtac agcctagtta ttgggaattt ctttaaaaga gttcctggga ttctgataag     1920

aagccaggtt gagaaccact acattagaag actgaatggt ttaatttaca tcctatgtta     1980

tgattggtct aagggataag atttggggtc taacctttcc tttcactcta gttagtcata     2040

gtccttgact tatgcctata tctttgtaag aaatagtatg tttcatttgt gatagtattg     2100

gtagggctga atatggatgg catctactgt aaaacaagtc taccttgtca gatgtgcaaa     2160

agctttcact cttgttctca aataaacttt tgtgggtttt tttttttttt tttttttgac     2220

tctggctatt tagatctttg actgtgtctt tggtagcaga actccagtgt caggattttt     2280

aaggaaatag tttcttatat ttagattatt ccttaaaaaa aaaaatccta gaagcattct     2340

gtattttttg tctgttggtc tcctttgctg ggagggagga gtgggatgcc tacagtttcc     2400

ttccttttgg ggaaagcaca cagcagacct taaaatattt ttgactcttg ggctgggtgc     2460

ggtggctcac acctgtaatc ccagcacttt gggaggccga agcgggcgga tcacgaggtc     2520

aggagatcga gaccatcctg gcgaacacag tgaaacccca tctctactaa aaatgcaaaa     2580

aattagctga gcgtggtggc gggtgccggt agtcccagct actcgggagg ctgaggcagg     2640

agaatggcat gaacctggga ggcggagctt acagtgagct gagatagtgc cactgcactc     2700

cagcctgggc gacagagcga gactccatct caaaaaaaaa aaatattttt gactcttaac     2760

agtttgagat tgctagagat ggaatagtac tgctctgttg cgccactgca ctccagcagc     2820

ctgggcgaca gagcgagact ctgtcaaaaa aaaaaaaaaa aagaaagaat agtactgctc     2880

ttaaaaagat tatttacgta tttatgaaac tgcagtggga tgcctagttt ccttccctct     2940

gaggaaagca cacagcagac cttaaaatat ttttgactct catagtttga cattgctgga     3000

gacagaatag tactgctctt aaaaagatta tttaagtatt tatatatttt atttatttat     3060

ttatttattt atttatttat tgacaggatc ttgctctgtc acccaggctg gagtgcagcg     3120

gcctgatcaa agctcagtgc agcctcgaac ttctggggtc aagccatctt cctgcttcag     3180

ccttactagt acctgggact ataggtgcat gccaccattc ccagctaatt taaaacattt     3240

ttattttgta atgatggctt cttgctatgt tgcccaggct ggcctcaagc agtcctcctg     3300

gcctcaagca gtccttctgc cttggcctcc caaagtgctg ggattatagg tatcaagcaa     3360

ttctcctgcc tcagcctccc cagtagctgg gactacaggc atgcaccacc atgcccatct     3420

aagttttgta tttttagtgg agatggggtt ttgccatgat gggcaggctg gtctcgaact     3480

cctgacctca ggtaatccac ccacctcagc ctcccaaagt gctgggatta caggcatgag     3540

ccctggcacc tggcaatata gagtattctt gacatcttga cctgtgcagt aaagaagata     3600

attaaaatga gcgataaata gtctaagctt gaaagttaaa gagcctaagc ttgaaacact     3660

ctgtgactta gtttttgcat ttattctgtc ttctatgccc cccaacctta ctccaaatta     3720

atgaggcatt attttattta tttatttttt tgagacagag tcttgctctg tcgtccaggc     3780

tggagtgcag tggcacaatc ttggctcact gctacctccg cctccagggt tcaagcaatt     3840

attccgcctc agcctctcga gtagctgaga ctacaggcgc gtgctaccac acccagctag     3900

ttttttttta ttttcaatag agaccgggtt tcaccatatt ggccaggctg gactcaaact     3960

cctgacttcg taatccacct gcctcagcct cccaaagtgc taggattaca ggcgtgagcc     4020

actgcacccg gcctaatgag gcattattgc ttaaaaattc acatcaagct gggcatggtg     4080

atatgcacct ttagtcccag ctgcttggga ggcttagagg cagcaggatc gcttgaagcc     4140

agaagttcaa ggctacagta tgctatgatc atttctgtga atggccactg cacttcagcc     4200

tgagtaacgt agcaagacgc tgtctccaac agaaaattga catctgaagc cttgactaca     4260

gggggactat actggtttat gtgaagtgtg gggagagagc aggattgtgc ttctttgtac     4320

acatttgctt ctcccaggat agtgtcatag tgcctaggaa ggtgatgtgt gtgtcagata     4380

caatgatagt gaaaagaagg gattggaatt ttcatacctg tgtcagtcta aatgagcatt     4440

accttgtctg aattgtctaa gtggtaagct tcgtgatttg aaacagtttt cactttgaaa     4500

aactgcttcc gtggattaaa agttgtcacc actaaagtgg gctgtggtgg agtcgatgct     4560

gatcctcact tagggcagtg gcctccaagg ggaagagggc acacaggatg gctgggtggg     4620

ggtgggaaga aaagattagg cctttgattt atattcattt tgaggctcag ccttatttag     4680

tttctcactt tggatgtatt ttatatatat acatcaaata tacatcaata ttagttcatt     4740

agtacatgta ggtcattaat ttataaataa aaggttgaac cacaataaac tgctgataat     4800

tgtttttgat ctgtaaaa                                                   4818


<210>  2012
<211>  13509
<212>  DNA
<213>  homo sapiens

<400>  2012
ggggcatttc cgggtccggg ccgagcgggc gcacgcgcgg gagcgggact cggcggcatg       60

gcgggctccg gagccggtgt gcgttgctcc ctgctgcggc tgcaggagac cttgtccgct      120

gcggaccgct gcggtgctgc cctggccggt catcaactga tccgcggcct ggggcaggaa      180

tgcgtcctga gcagcagccc cgcggtgctg gcattacaga catctttagt tttttccaga      240

gatttcggtt tgcttgtatt tgtccggaag tcactcaaca gtattgaatt tcgtgaatgt      300

agagaagaaa tcctaaagtt tttatgtatt ttcttagaaa aaatgggcca gaagatcgca      360

ccttactctg ttgaaattaa gaacacttgt accagtgttt atacaaaaga tagagctgct      420

aaatgtaaaa ttccagccct ggaccttctt attaagttac ttcagacttt tagaagttct      480

agactcatgg atgaatttaa aattggagaa ttatttagta aattctatgg agaacttgca      540

ttgaaaaaaa aaataccaga tacagtttta gaaaaagtat atgagctcct aggattattg      600

ggtgaagttc atcctagtga gatgataaat aatgcagaaa acctgttccg cgcttttctg      660

ggtgaactta agacccagat gacatcagca gtaagagagc ccaaactacc tgttctggca      720

ggatgtctga aggggttgtc ctcacttctg tgcaacttca ctaagtccat ggaagaagat      780

ccccagactt caagggagat ttttaatttt gtactaaagg caattcgtcc tcagattgat      840

ctgaagagat atgctgtgcc ctcagctggc ttgcgcctat ttgccctgca tgcatctcag      900

tttagcacct gccttctgga caactacgtg tctctatttg aagtcttgtt aaagtggtgt      960

gcccacacaa atgtagaatt gaaaaaagct gcactttcag ccctggaatc ctttctgaaa     1020

caggtttcta atatggtggc gaaaaatgca gaaatgcata aaaataaact gcagtacttt     1080

atggagcagt tttatggaat catcagaaat gtggattcga acaacaagga gttatctatt     1140

gctatccgtg gatatggact ttttgcagga ccgtgcaagg ttataaacgc aaaagatgtt     1200

gacttcatgt acgttgagct cattcagcgc tgcaagcaga tgttcctcac ccagacagac     1260

actggtgacg accgtgttta tcagatgcca agcttcctcc agtctgttgc aagcgtcttg     1320

ctgtaccttg acacagttcc tgaggtgtat actccagttc tggagcacct cgtggtgatg     1380

cagatagaca gtttcccaca gtacagtcca aaaatgcagc tggtgtgttg cagagccata     1440

gtgaaggtgt tcctagcttt ggcagcaaaa gggccagttc tcaggaattg cattagtact     1500

gtggtgcatc agggtttaat cagaatatgt tctaaaccag tggtccttcc aaagggccct     1560

gagtctgaat ctgaagacca ccgtgcttca ggggaagtca gaactggcaa atggaaggtg     1620

cccacataca aagactacgt ggatctcttc agacatctcc tgagctctga ccagatgatg     1680

gattctattt tagcagatga agcatttttc tctgtgaatt cctccagtga aagtctgaat     1740

catttacttt atgatgaatt tgtaaaatcc gttttgaaga ttgttgagaa attggatctt     1800

acacttgaaa tacagactgt tggggaacaa gagaatggag atgaggcgcc tggtgtttgg     1860

atgatcccaa cttcagatcc agcggctaac ttgcatccag ctaaacctaa agatttttcg     1920

gctttcatta acctggtgga attttgcaga gagattctcc ctgagaaaca agcagaattt     1980

tttgaaccat gggtgtactc attttcatat gaattaattt tgcaatctac aaggttgccc     2040

ctcatcagtg gtttctacaa attgctttct attacagtaa gaaatgccaa gaaaataaaa     2100

tatttcgagg gagttagtcc aaagagtctg aaacactctc ctgaagaccc agaaaagtat     2160

tcttgctttg ctttatttgt gaaatttggc aaagaggtgg cagttaaaat gaagcagtac     2220

aaagatgaac ttttggcctc ttgtttgacc tttcttctgt ccttgccaca caacatcatt     2280

gaactcgatg ttagagccta cgttcctgca ctgcagatgg ctttcaaact gggcctgagc     2340

tataccccct tggcagaagt aggcctgaat gctctagaag aatggtcaat ttatattgac     2400

agacatgtaa tgcagcctta ttacaaagac attctcccct gcctggatgg atacctgaag     2460

acttcagcct tgtcagatga gaccaagaat aactgggaag tgtcagctct ttctcgggct     2520

gcccagaaag gatttaataa agtggtgtta aagcatctga agaagacaaa gaacctttca     2580

tcaaacgaag caatatcctt agaagaaata agaattagag tagtacaaat gcttggatct     2640

ctaggaggac aaataaacaa aaatcttctg acagtcacgt cctcagatga gatgatgaag     2700

agctatgtgg cctgggacag agagaagcgg ctgagctttg cagtgccctt tagagagatg     2760

aaacctgtca ttttcctgga tgtgttcctg cctcgagtca cagaattagc gctcacagcc     2820

agtgacagac aaactaaagt tgcagcctgt gaacttttac atagcatggt tatgtttatg     2880

ttgggcaaag ccacgcagat gccagaaggg ggacagggag ccccacccat gtaccagctc     2940

tataagcgga cgtttcctgt gctgcttcga cttgcgtgtg atgttgatca ggtgacaagg     3000

caactgtatg agccactagt tatgcagctg attcactggt tcactaacaa caagaaattt     3060

gaaagtcagg atactgttgc cttactagaa gctatattgg atggaattgt ggaccctgtt     3120

gacagtactt taagagattt ttgtggtcgg tgtattcgag aattccttaa atggtccatt     3180

aagcaaataa caccacagca gcaggagaag agtccagtaa acaccaaatc gcttttcaag     3240

cgactttata gccttgcgct tcaccccaat gctttcaaga ggctgggagc atcacttgcc     3300

tttaataata tctacaggga attcagggaa gaagagtctc tggtggaaca gtttgtgttt     3360

gaagccttgg tgatatacat ggagagtctg gccttagcac atgcagatga gaagtcctta     3420

ggtacaattc aacagtgttg tgatgccatt gatcacctat gccgcatcat tgaaaagaag     3480

catgtttctt taaataaagc aaagaaacga cgtttgccgc gaggatttcc accttccgca     3540

tcattgtgtt tattggatct ggtcaagtgg cttttagctc attgtgggag gccccagaca     3600

gaatgtcgac acaaatccat tgaactcttt tataaattcg ttcctttatt gccaggcaac     3660

agatccccta atttgtggct gaaagatgtt ctcaaggaag aaggtgtctc ttttctcatc     3720

aacacctttg aggggggtgg ctgtggccag ccctcgggca tcctggccca gcccaccctc     3780

ttgtaccttc gggggccatt cagcctgcag gccacgctat gctggctgga cctgctcctg     3840

gccgcgttgg agtgctacaa cacgttcatt ggcgagagaa ctgtaggagc gctccaggtc     3900

ctaggtactg aagcccagtc ttcacttttg aaagcagtgg ctttcttctt agaaagcatt     3960

gccatgcatg acattatagc agcagaaaag tgctttggca ctggggcagc aggtaacaga     4020

acaagcccac aagagggaga aaggtacaac tacagcaaat gcaccgttgt ggtccggatt     4080

atggagttta ccacgactct gctaaacacc tccccggaag gatggaagct cctgaagaag     4140

gacttgtgta atacacacct gatgagagtc ctggtgcaga cgctgtgtga gcccgcaagc     4200

ataggtttca acatcggaga cgtccaggtt atggctcatc ttcctgatgt ttgtgtgaat     4260

ctgatgaaag ctctaaagat gtccccatac aaagatatcc tagagaccca tctgagagag     4320

aaaataacag cacagagcat tgaggagctt tgtgccgtca acttgtatgg ccctgacgcg     4380

caagtggaca ggagcaggct ggctgctgtt gtgtctgcct gtaaacagct tcacagagct     4440

gggcttctgc ataatatatt accgtctcag tccacagatt tgcatcattc tgttggcaca     4500

gaacttcttt ccctggttta taaaggcatt gcccctggag atgagagaca gtgtctgcct     4560

tctctagacc tcagttgtaa gcagctggcc agcggacttc tggagttagc ctttgctttt     4620

ggaggactgt gtgagcgcct tgtgagtctt ctcctgaacc cagcggtgct gtccacggcg     4680

tccttgggca gctcacaggg cagcgtcatc cacttctccc atggggagta tttctatagc     4740

ttgttctcag aaacgatcaa cacggaatta ttgaaaaatc tggatcttgc tgtattggag     4800

ctcatgcagt cttcagtgga taataccaaa atggtgagtg ccgttttgaa cggcatgtta     4860

gaccagagct tcagggagcg agcaaaccag aaacaccaag gactgaaact tgcgactaca     4920

attctgcaac actggaagaa gtgtgattca tggtgggcca aagattcccc tctcgaaact     4980

aaaatggcag tgctggcctt actggcaaaa attttacaga ttgattcatc tgtatctttt     5040

aatacaagtc atggttcatt ccctgaagtc tttacaacat atattagtct acttgctgac     5100

acaaagctgg atctacattt aaagggccaa gctgtcactc ttcttccatt cttcaccagc     5160

ctcactggag gcagtctgga ggaacttaga cgtgttctgg agcagctcat cgttgctcac     5220

ttccccatgc agtccaggga atttcctcca ggaactccgc ggttcaataa ttatgtggac     5280

tgcatgaaaa agtttctaga tgcattggaa ttatctcaaa gccctatgtt gttggaattg     5340

atgacagaag ttctttgtcg ggaacagcag catgtcatgg aagaattatt tcaatccagt     5400

ttcaggagga ttgccagaag gggttcatgt gtcacacaag taggccttct ggaaagcgtg     5460

tatgaaatgt tcaggaagga tgacccccgc ctaagtttca cacgccagtc ctttgtggac     5520

cgctccctcc tcactctgct gtggcactgt agcctggatg ctttgagaga attcttcagc     5580

acaattgtgg tggatgccat tgatgtgttg aagtccaggt ttacaaagct aaatgaatct     5640

acctttgata ctcaaatcac caagaagatg ggctactata agattctaga cgtgatgtat     5700

tctcgccttc ccaaagatga tgttcatgct aaggaatcaa aaattaatca agttttccat     5760

ggctcgtgta ttacagaagg aaatgaactt acaaagacat tgattaaatt gtgctacgat     5820

gcatttacag agaacatggc aggagagaat cagctgctgg agaggagaag actttaccat     5880

tgtgcagcat acaactgcgc catatctgtc atctgctgtg tcttcaatga gttaaaattt     5940

taccaaggtt ttctgtttag tgaaaaacca gaaaagaact tgcttatttt tgaaaatctg     6000

atcgacctga agcgccgcta taattttcct gtagaagttg aggttcctat ggaaagaaag     6060

aaaaagtaca ttgaaattag gaaagaagcc agagaagcag caaatgggga ttcagatggt     6120

ccttcctata tgtcttccct gtcatatttg gcagacagta ccctgagtga ggaaatgagt     6180

caatttgatt tctcaaccgg agttcagagc tattcataca gctcccaaga ccctagacct     6240

gccactggtc gttttcggag acgggagcag cgggacccca cggtgcatga tgatgtgctg     6300

gagctggaga tggacgagct caatcggcat gagtgcatgg cgcccctgac ggccctggtc     6360

aagcacatgc acagaagcct gggcccgcct caaggagaag aggattcagt gccaagagat     6420

cttccttctt ggatgaaatt cctccatggc aaactgggaa atccaatagt accattaaat     6480

atccgtctct tcttagccaa gcttgttatt aatacagaag aggtctttcg cccttacgcg     6540

aagcactggc ttagcccctt gctgcagctg gctgcttctg aaaacaatgg aggagaagga     6600

attcactaca tggtggttga gatagtggcc actattcttt catggacagg cttggccact     6660

ccaacagggg tccctaaaga tgaagtgtta gcaaatcgat tgcttaattt cctaatgaaa     6720

catgtctttc atccaaaaag agctgtgttt agacacaacc ttgaaattat aaagaccctt     6780

gtcgagtgct ggaaggattg tttatccatc ccttataggt taatatttga aaagttttcc     6840

ggtaaagatc ctaattctaa agacaactca gtagggattc aattgctagg catcgtgatg     6900

gccaatgacc tgcctcccta tgacccacag tgtggcatcc agagtagcga atacttccag     6960

gctttggtga ataatatgtc ctttgtaaga tataaagaag tgtatgccgc tgcagcagaa     7020

gttctaggac ttatacttcg atatgttatg gagagaaaaa acatactgga ggagtctctg     7080

tgtgaactgg ttgcgaaaca attgaagcaa catcagaata ctatggagga caagtttatt     7140

gtgtgcttga acaaagtgac caagagcttc cctcctcttg cagacaggtt catgaatgct     7200

gtgttctttc tgctgccaaa atttcatgga gtgttgaaaa cactctgtct ggaggtggta     7260

ctttgtcgtg tggagggaat gacagagctg tacttccagt taaagagcaa ggacttcgtt     7320

caagtcatga gacatagaga tgatgaaaga caaaaagtat gtttggacat aatttataag     7380

atgatgccaa agttaaaacc agtagaactc cgagaacttc tgaaccccgt tgtggaattc     7440

gtttcccatc cttctacaac atgtagggaa caaatgtata atattctcat gtggattcat     7500

gataattaca gagatccaga aagtgagaca gataatgact cccaggaaat atttaagttg     7560

gcaaaagatg tgctgattca aggattgatc gatgagaacc ctggacttca attaattatt     7620

cgaaatttct ggagccatga aactaggtta ccttcaaata ccttggaccg gttgctggca     7680

ctaaattcct tatattctcc taagatagaa gtgcactttt taagtttagc aacaaatttt     7740

ctgctcgaaa tgaccagcat gagcccagat tatccaaacc ccatgttcga gcatcctctg     7800

tcagaatgcg aatttcagga atataccatt gattctgatt ggcgtttccg aagtactgtt     7860

ctcactccga tgtttgtgga gacccaggcc tcccagggca ctctccagac ccgtacccag     7920

gaagggtccc tctcagctcg ctggccagtg gcagggcaga taagggccac ccagcagcag     7980

catgacttca cactgacaca gactgcagat ggaagaagct catttgattg gctgaccggg     8040

agcagcactg acccgctggt cgaccacacc agtccctcat ctgactcctt gctgtttgcc     8100

cacaagagga gtgaaaggtt acagagagca cccttgaagt cagtggggcc tgattttggg     8160

aaaaaaaggc tgggccttcc aggggacgag gtggataaca aagtgaaagg tgcggccggc     8220

cggacggacc tactacgact gcgcagacgg tttatgaggg accaggagaa gctcagtttg     8280

atgtatgcca gaaaaggcgt tgctgagcaa aaacgagaga aggaaatcaa gagtgagtta     8340

aaaatgaagc aggatgccca ggtcgttctg tacagaagct accggcacgg agaccttcct     8400

gacattcaga tcaagcacag cagcctcatc accccgttac aggccgtggc ccagagggac     8460

ccaataattg caaaacagct ctttagcagc ttgttttctg gaattttgaa agagatggat     8520

aaatttaaga cactgtctga aaaaaacaac atcactcaaa agttgcttca agacttcaat     8580

cgttttctta ataccacctt ctctttcttt ccaccctttg tctcttgtat tcaggacatt     8640

agctgtcagc acgcagccct gctgagcctc gacccagcgg ctgttagcgc tggttgcctg     8700

gccagcctac agcagcccgt gggcatccgc ctgctagagg aggctctgct ccgcctgctg     8760

cctgctgagc tgcctgccaa gcgagtccgt gggaaggccc gcctccctcc tgatgtcctc     8820

agatgggtgg agcttgctaa gctgtataga tcaattggag aatacgacgt cctccgtggg     8880

atttttacca gtgagatagg aacaaagcaa atcactcaga gtgcattatt agcagaagcc     8940

agaagtgatt attctgaagc tgctaagcag tatgatgagg ctctcaataa acaagactgg     9000

gtagatggtg agcccacaga agccgagaag gatttttggg aacttgcatc ccttgactgt     9060

tacaaccacc ttgctgagtg gaaatcactt gaatactgtt ctacagccag tatagacagt     9120

gagaaccccc cagacctaaa taaaatctgg agtgaaccat tttatcagga aacatatcta     9180

ccttacatga tccgcagcaa gctgaagctg ctgctccagg gagaggctga ccagtccctg     9240

ctgacattta ttgacaaagc tatgcacggg gagctccaga aggcgattct agagcttcat     9300

tacagtcaag agctgagtct gctttacctc ctgcaagatg atgttgacag agccaaatat     9360

tacattcaaa atggcattca gagttttatg cagaattatt ctagtattga tgtcctctta     9420

caccaaagta gactcaccaa attgcagtct gtacaggctt taacagaaat tcaggagttc     9480

atcagcttta taagcaaaca aggcaattta tcatctcaag ttccccttaa gagacttctg     9540

aacacctgga caaacagata tccagatgct aaaatggacc caatgaacat ctgggatgac     9600

atcatcacaa atcgatgttt ctttctcagc aaaatagagg agaagcttac ccctcttcca     9660

gaagataata gtatgaatgt ggatcaagat ggagacccca gtgacaggat ggaagtgcaa     9720

gagcaggaag aagatatcag ctccctgatc aggagttgca agttttccat gaaaatgaag     9780

atgatagaca gtgcccggaa gcagaacaat ttctcacttg ctatgaaact actgaaggag     9840

ctgcataaag agtcaaaaac cagagacgat tggctggtga gctgggtgca gagctactgc     9900

cgcctgagcc actgccggag ccggtcccag ggctgctctg agcaggtgct cactgtgctg     9960

aaaacagtct ctttgttgga tgagaacaac gtgtcaagct acttaagcaa aaatattctg    10020

gctttccgtg accagaacat tctcttgggt acaacttaca ggatcatagc gaatgctctc    10080

agcagtgagc cagcctgcct tgctgaaatc gaggaggaca aggctagaag aatcttagag    10140

ctttctggat ccagttcaga ggattcagag aaggtgatcg cgggtctgta ccagagagca    10200

ttccagcacc tctctgaggc tgtgcaggcg gctgaggagg aggcccagcc tccctcctgg    10260

agctgtgggc ctgcagctgg ggtgattgat gcttacatga cgctggcaga tttctgtgac    10320

caacagctgc gcaaggagga agagaatgca tcagttattg attctgcaga actgcaggcg    10380

tatccagcac ttgtggtgga gaaaatgttg aaagctttaa aattaaattc caatgaagcc    10440

agattgaagt ttcctagatt acttcagatt atagaacggt atccagagga gactttgagc    10500

ctcatgacaa aagagatctc ttccgttccc tgctggcagt tcatcagctg gatcagccac    10560

atggtggcct tactggacaa agaccaagcc gttgctgttc agcactctgt ggaagaaatc    10620

actgataact acccgcaggc tattgtttat cccttcatca taagcagcga aagctattcc    10680

ttcaaggata cttctactgg tcataagaat aaggagtttg tggcaaggat taaaagtaag    10740

ttggatcaag gaggagtgat tcaagatttt attaatgcct tagatcagct ctctaatcct    10800

gaactgctct ttaaggattg gagcaatgat gtaagagctg aactagcaaa aacccctgta    10860

aataaaaaaa acattgaaaa aatgtatgaa agaatgtatg cagccttggg tgacccaaag    10920

gctccaggcc tgggggcctt tagaaggaag tttattcaga cttttggaaa agaatttgat    10980

aaacattttg ggaaaggagg ttctaaacta ctgagaatga agctcagtga cttcaacgac    11040

attaccaaca tgctactttt aaaaatgaac aaagactcaa agccccctgg gaatctgaaa    11100

gaatgttcac cctggatgag cgacttcaaa gtggagttcc tgagaaatga gctggagatt    11160

cccggtcagt atgacggtag gggaaagcca ttgccagagt accacgtgcg aatcgccggg    11220

tttgatgagc gggtgacagt catggcgtct ctgcgaaggc ccaagcgcat catcatccgt    11280

ggccatgacg agagggaaca ccctttcctg gtgaagggtg gcgaggacct gcggcaggac    11340

cagcgcgtgg agcagctctt ccaggtcatg aatgggatcc tggcccaaga ctccgcctgc    11400

agccagaggg ccctgcagct gaggacctat agcgttgtgc ccatgacctc caggttagga    11460

ttaattgagt ggcttgaaaa tactgttacc ttgaaggacc ttcttttgaa caccatgtcc    11520

caagaggaga aggcggctta cctgagtgat cccagggcac cgccgtgtga atataaagat    11580

tggctgacaa aaatgtcagg aaaacatgat gttggagctt acatgctaat gtataagggc    11640

gctaatcgta ctgaaacagt cacgtctttt agaaaacgag aaagtaaagt gcctgctgat    11700

ctcttaaagc gggccttcgt gaggatgagt acaagccctg aggctttcct ggcgctccgc    11760

tcccacttcg ccagctctca cgctctgata tgcatcagcc actggatcct cgggattgga    11820

gacagacatc tgaacaactt tatggtggcc atggagactg gcggcgtgat cgggatcgac    11880

tttgggcatg cgtttggatc cgctacacag tttctgccag tccctgagtt gatgcctttt    11940

cggctaactc gccagtttat caatctgatg ttaccaatga aagaaacggg ccttatgtac    12000

agcatcatgg tacacgcact ccgggccttc cgctcagacc ctggcctgct caccaacacc    12060

atggatgtgt ttgtcaagga gccctccttt gattggaaaa attttgaaca gaaaatgctg    12120

aaaaaaggag ggtcatggat tcaagaaata aatgttgctg aaaaaaattg gtacccccga    12180

cagaaaatat gttacgctaa gagaaagtta gcaggtgcca atccagcagt cattacttgt    12240

gatgagctac tcctgggtca tgagaaggcc cctgccttca gagactatgt ggctgtggca    12300

cgaggaagca aagatcacaa cattcgtgcc caagaaccag agagtgggct ttcagaagag    12360

actcaagtga agtgcctgat ggaccaggca acagacccca acatccttgg cagaacctgg    12420

gaaggatggg agccctggat gtgaggtctg tgggagtctg cagatagaaa gcattacatt    12480

gtttaaagaa tctactatac tttggttggc agcattccat gagctgattt tcctgaaaca    12540

ctaaagagaa atgtcttttg tgctacagtt tcgtagcatg agtttaaatc aagattatga    12600

tgagtaaatg tgtatgggtt aaatcaaaga taaggttata gtaacatcaa agattaggtg    12660

aggtttatag aaagatagat atccaggctt accaaagtat taagtcaaga atataatatg    12720

tgatcagctt tcaaagcatt tacaagtgct gcaagttagt gaaacagctg tctccgtaaa    12780

tggaggaaat gtggggaagc cttggaatgc ccttctggtt ctggcacatt ggaaagcaca    12840

ctcagaaggc ttcatcacca agattttggg agagtaaagc taagtatagt tgatgtaaca    12900

ttgtagaagc agcataggaa caataagaac aataggtaaa gctataatta tggcttatat    12960

ttagaaatga ctgcatttga tattttagga tatttttcta ggttttttcc tttcatttta    13020

ttctcttcta gttttgacat tttatgatag atttgctctc tagaaggaaa cgtctttatt    13080

taggagggca aaaattttgg tcatagcatt cacttttgct attccaatct acaactggaa    13140

gatacataaa agtgctttgc attgaatttg ggataacttc aaaaatccca tggttgttgt    13200

tagggatagt actaagcatt tcagttccag gagaataaaa gaaattccta tttgaaatga    13260

attcctcatt tggaggaaaa aaagcatgca ttctagcaca acaagatgaa attatggaat    13320

acaaaagtgg ctccttccca tgtgcagtcc ctgtcccccc ccgccagtcc tccacaccca    13380

aactgtttct gattggcttt tagctttttg ttgttttttt ttttccttct aacacttgta    13440

tttggaggct cttctgtgat tttgagaagt atactcttga gtgtttaata aagttttttt    13500

ccaaaagta                                                            13509


<210>  2013
<211>  9078
<212>  DNA
<213>  homo sapiens

<400>  2013
gcgcgccccg gcgccgcgcc cggccgggag ccgcctgttg atcgccgcgc tcgccccggc       60

cacggcgccg cccctgttct cccggccccg ctccaccggg gctgacggac tgacggccag      120

cacagccggc tccgggatga gcgcacggac ggtattctga agtctcagga aactggacca      180

tttaaatgtg catggcccat gagaaaggct tataagaagc catggcactc ccctttcaaa      240

aagagctgga gaaatacaag aacattgatg aagatgagct tcttggcaaa ctctcagaag      300

aggaactgaa acagttggaa aatgttctag atgacctaga tcctgagagt gccatgctgc      360

cagctggatt tcgacagaaa gaccagacac agaaggcagc caccggcccc tttgaccgcg      420

agcacctcct catgtacctg gagaaggagg ctttggaaca gaaagacaga gaggactttg      480

tgcccttcac tggagaaaag aaagggagag tctttatccc taaagaaaag cctatagaaa      540

ctcgtaaaga agaaaaagtg acccttgacc cagaactgga agaagctttg gccagtgcct      600

ctgacaccga actctatgat cttgcagctg tccttggagt acacaatttg ctcaacaatc      660

caaagttcga tgaagaaaca gccaacaata aaggtggcaa aggacctgtc agaaatgttg      720

tcaaaggtga aaaagtaaag ccagtatttg aggaaccacc aaatcccaca aatgtggaaa      780

taagcctgca gcagatgaaa gccaatgatc ctagcttgca agaagtcaac ctcaacaaca      840

ttaaggcttt tgcagacatg ctgaaagtaa acaagacctt gacaagtcta aacatagaat      900

ccaattttat cactggaact gggatcctgg ccctggtaga ggcactgaaa gaaaatgaca      960

ccttgacaga aatcaagatt gacaaccaga ggcagcagtt gggaacagct gtagagatgg     1020

aaattgccca gatgctggag gagaattcaa ggatcctcaa gtttggatac cagtttacca     1080

agcaagggcc acgaacaagg gtggcagctg ccatcacaaa gaataatgac ctggttcgta     1140

agaagagagt tgaagcagac cgaaggtaaa cttccttgag gagaagtgaa gtttcactgt     1200

ggtatggcca ttgaaaaaca aaaactcttc ttcttcccca tcaggaccat tttatcaaag     1260

ttcgttcatt tccgttaacc acataactaa taatttaatt gttattcttt tttagcacta     1320

cttatttatc ttggattttg taatatatgc aattgtttta tttgctcatg ggcacttctg     1380

gcaacttgac aaatggaccg atgcagattt tagagagtga cgacatggaa aatgaattta     1440

accactttct tattgggttg tcttgctttc ttacatgaac ttgttttttt aatcactgaa     1500

aggaatttag tgtataatat gtgtttgtaa ctgtgattat gatagaggcc tatctctgtt     1560

tacatgcata gctttgagtt aggctaaata catcagaagt gttctactga ccacataaga     1620

agttagtatt gccaatcttt cactgcatgt gaaaatgtga ccaatttagc acaaattctc     1680

tcttagttcc agaaaaatca gtaaatgcac atgccctgtt gattggagat cagtagtgtc     1740

atcttcataa agcaagacaa cattatgaca ctttaaaaca gtagcaaaga agtctattta     1800

ttaacccaca aatgtagcat caagccagac tcacaggtag caaaatgaat tacacaccta     1860

cttttactga ctattcaaca taaattgaat ctttaacatg actttaaagg ctatttacaa     1920

agctgtttta aagtttttca aacatgatag aaattttcta aattttagta agagagaagc     1980

ttttaaaaca gtacattcct gaataaaaca acaatattgt atcttaatca aggctgtctg     2040

atgcagatga ttgcattttt tggcaaattt tagaagcatt tattgctttg tctttagtgt     2100

aacaagatca ctggattaaa tataaacatt caggttaatt atctagattt ttgtccacag     2160

tatatgatcc atccagacat ttgcaaacgt caggagaaaa atgtgaatta tttatccaga     2220

tgcatgtcat ctcaaggaca aagcctgtga aagtacaagt gagatggttg cattgtagta     2280

tgcattaatc tttcaatgta gtggtgtaaa aatgcagtgc taaactaatg aagcaggtga     2340

ctgcagcctt tggctcaagc tcacaactct gataactgtc agtgcctgag gttgtgattg     2400

gtgacattct gacactgccc aaggcaactc accctctatt cctcctttct cccctccctt     2460

tcttccaatt cattgtcttt tttttcctct tttctctgta atttgttact aaacaaattc     2520

cagaatttgt ttagtagctg agtgttcctg agttgcctag tagcaataaa acaagtgaat     2580

aggaaaataa ttaatatatt attctattta gcttgtaaaa cacatggaat ctgtttaaga     2640

tagcccttgt aaaattgaac atttacctgt attgtaagta cccacatctg tgtctctgaa     2700

gtcctttgaa acatctcatt atcttgaaat ttttttaatg tttgagaaca ccataagcag     2760

aatattctaa cacctttggc ccctgaaaat cctttaatta gtttatggct tcatctcctt     2820

atctatttaa aaaacatagt aaataatgtt tatggttttc agtctgattt ttccttccct     2880

ttcacccatt taggtgtgat gtgttggagt caacttgtac aggcttgcca actgttatat     2940

tttcaagaat tttgcaaact ggttgttcaa tacagccatt atttaaaatt aaatgatgtg     3000

cacttacaac tgaatgaatt atattaagga cagaagtaac aaatactgta ctcaaaaatc     3060

ttacatttta ctattttcta acctcttaga ttatttacat ctagtaggta tgtatgtaga     3120

aatattacca aacagtatgc tactgaacgt atcctctcaa ctccatgttc actaccttct     3180

tgttactaca gtggcttgaa attggccatg gtagaaatat ttacaccaca gaaattagca     3240

atatgtaaga aattggggtt ttctccctct ccagattgct ggttgataaa cattcatcag     3300

cacaccactg ggtgaaatta tacatttttt tatacatatg tttcgcttat catgttgccg     3360

aagggaagaa catttctctt agatgtcttt tctcctcttt ggatttgtta caaacctgtt     3420

taagtgctga gtccctgacc tgcctctcca agtaagcctt tttccttttt tttttttttt     3480

ttcttactct cattcttgcc ttgactctta aaatcctgga ccctatagag cattccttgc     3540

agccccacag tgctgtgggc tgggggctaa agcagttctt ggcaaactct ggcagaaagc     3600

aagaaaaaaa gaatcagaat tcaatcatgg ctgtttcttt tgtacaagca gttgttgata     3660

gtattaaagc aagataatgg gacattatca aaaatatagc actgttttta ccttatgaaa     3720

tagttgggtt gcatgcaaca gagtctatga aatcaaatgt tttttactaa tcagtttgtt     3780

ttcttattac ctgtgttttt aaagtggctt gaaaggtggc atttccatga gtgtgcacat     3840

attgatgata acccttagaa aaacatacac ttgaggagcc tatccatcat ttaattagcc     3900

taggacttca tctccctctc tgcccaaagt gtggaagtgg tagctctttc atgatcatgg     3960

gcacagttaa tcctttgcta tccattgtga tggggcataa tgtatataaa atatttttct     4020

atgtatttgt tctgccagat actgtgttga gatatttggc aatatctgga taactgactg     4080

aagggagata acttctcccc aggcctatct ccctccccct tttagagttg tgcaggtcca     4140

ctttaagtgt aaaatcactc acctggactt gtgggcttgt atcaccaaca tctattatgg     4200

cacatgtaga tgacatttag gagaaaaacc ttagaagtct agaaatcata tgattagttc     4260

agcactgcag ctccccatct gcttatagtg tataactgga agctctttca tcctcatcag     4320

catgattaaa tgacttcgtt tctttcatct ttggagggta taatgtaaat aagtgtcgtg     4380

tgtgtatgtg tgtgtgtact gtcagatatc taactaggta tttggctaca tctggacaac     4440

tgattgaagg gagatgctct ctccccagtc ctcttccctt gtccttttta gaattgctgc     4500

aggcccaggt taaatatgaa attactccct aggctttgca gtttatgtta ccaaccacca     4560

cattttatag ctatgtagag gatgactctt aggaaataaa tattagaagc ctagaaatca     4620

tttagttgtt ctagcaccaa atctatccat ttgcctaatg tatttaacat tccatcctca     4680

tcaacatgat gaagcccctt tcttccatct ttgtagggca cattgtatat aaatattttg     4740

tacataaaga tcatcaaata ccataatggg gtatttggct tcatctggaa aattgactgg     4800

agggagatgc tgtctcccag ccctgcttcc ctcgtccctg tccaagttgc tgcaggccca     4860

ggttagaaga ttaccaacct ggaggggcat gcagttcatc ttacaataaa agcccattca     4920

tttaaaaact cagaaatcat cccagtgcct gtactcctca aaccaatttc cctaagggaa     4980

gactggcaca ccagcccaaa gagcaggtgc ttctcttcca acagaaacat ggcccctgac     5040

agggcaccag cattagggaa accaatgtcc tccgaatagc tgccatgaga acatttcaga     5100

tgctcaaact gaaaattctt aaaaccaata ttaagcatca gcatgcttta agtgtaagat     5160

agccctttgg aatttacaaa cacatgtgca gctatttcct tcttcacaga tatgatgtac     5220

tcagccccct cctaggcact acgaagaaga cagaggaagc ataaaaattc tggactaata     5280

taattttata tgtgtttctg agattgggga gtagactgag tgcctttttt acaaagaaga     5340

tcccatattt aattcaagta tttatagcat cagcaaaaat gggcagaggg cgggaagttg     5400

agaacactag gttctgtgct atgttacctg tattcagtag aagtgtttct ggagtcaggt     5460

tttaagtcat gatcctgaag cttccttccc ctcttccact aatgatgcaa taatagctgt     5520

tttcatttta acgagcagag aactaagagg aaaggtccta gctctgcctt ccacttgcag     5580

cttcccttta cctcctctta ttgctttcat ctcaaatatc cctgctactc aaccaatcct     5640

aaagctaaag tactgagatg cacacaaagg aaaggtgtga gagtgcttgg aagcatccag     5700

ctgagcccac tggatgaaaa tcagacgata gggcctcctg ttgtaatata ctagccagag     5760

aaaagcgcca agaacttcag ggatattatt cactgcttta ttgctcccta accctagatc     5820

agattggatt ttactttgta gttcaggagt taagaagtca aattgctgac cgaggtgggg     5880

aaggatgatg gaaattaaag gtttacattt gtttaatggc agaactgaga tttgctcagc     5940

ttatctcttt cccatctgtc tgtaatagca atgactgaat aatcagtaga ccaatggaag     6000

aggagttgca agtttaaatt tgtaacctga ctctgggttc tgttctagga atagtgcatg     6060

ttttagaggc tttgccagtt gggatacatt gttgacttgg gggaggatga aggagagaac     6120

tgatgaccta gacatagaaa agagtagtta actaactaga tgttcttctg atctcttcca     6180

tggtagacat tctgagcaca ttggcccagt tagttggtat ggtgaagggg caccgtacta     6240

acagatttgg agactgaaac ctaatcccat caccaacact tagcaggtat atgatcatgg     6300

gcaattcatt caattgcctg ccaattatag actatatagg gggaagagca ctggatttgg     6360

agtcaagaaa cctggacact tggctccaca cttccttagc tgggtaactt tgggcaaacc     6420

gcttggtctc tcaagcctaa ggttcttcag ctataaaatg ggaataatac ttcactaact     6480

acctcacaga gttgtggtaa gaatataatc agataactgg ataaaaacac tatataaact     6540

ggaaagcgcc gtacaaatgt gagagatcag ttttattatc aaatcactgt tttccactgc     6600

ctcttgaatc ggctttattc taaccaacca ttacatcttt ctcatctttt ggagtatggg     6660

taattgaggc ttgggtgtgt catcagggac tggagttatt tcagctccca tgtagaggtg     6720

ggagaggtgg ttgatggggc agtggaagtt agataccagc gatgtatatg gtaggacatt     6780

ttcctgggtc actttgacag taccttggga aattgtcagt ccttgcagag ggcctaggct     6840

gggcacaagg gagaaagcga acagttgact aagaattgag gggagggtct ggagcgctac     6900

tgccctcctg tcattgctgt gggtgggaga ggctaagact tcaggtttga ctggaggcct     6960

aggagagaag agtgtcctta gggtttcaag aattttaatg cctagcagct gagtaacagg     7020

cattagttct gatagatagt gaaggggaga aagtgccacc tgttgtgaga tcacctctcc     7080

agggcagcag ctgccttgtt atcaccagca accttagccc tggtcagtaa tatttctgct     7140

aagaaaggtt ttgaagcatg gcctccaatg actttcataa gcccttggag gcaggactgt     7200

gtctcatcca tctttgtatc ttcagtacca tcttgtaagg tgccttgtac atagtaggtg     7260

cttaatgaac aaatgttgct tgaatttagc tgtcgtccag ccccacagag ttatgctcca     7320

tttgccacca tgtgatattt ttgagaaaca atagtgattt ggatgccagc tctatgtgac     7380

tttgggcaag actctccatc tatcttgtct tcatttcatc tgtaaaatga agtgagtaga     7440

ttcaatgctc cctaaggtcc cttccagctc caatacttga caagcttgtg attctaaatc     7500

gtttccgttg cctctgaaca tgggtgagta atgcctccac tgcagctgtt tctctccagg     7560

aggctttgtt cagaggaggt ctgactattg cacagccagt tttttcttcc tcttcagcag     7620

ttctttactg tcttcagaat ggttctggat aagcggcctt ttctgaaagg atatttaaaa     7680

atatatacta tttaggctgg gcccagtggc tcatgcctgt aatcccagca ctttgggagg     7740

tgaaggtggg tggatcacct gaggtcagga gttcaagacc agcctggcca acatggtgaa     7800

accccgtctc tactaaaaat acagaaatta gctgggccct gtggcaagag cctgttatcc     7860

cagctactgg ggaggctgag gcaggaaaat cgcttgaacc caggaggtgg aggttgtagt     7920

gagccgagat cacaccactg cactccagcc tgggtgacaa gaacgaaact ccatctcaaa     7980

aaataaaata aaatatatac tatcttgctc ctcagaacca gtggggaaga agagggaagg     8040

caaagaaaga aactgagcat agtaaacaca gcattttttt gtaggctctt atttaaaatg     8100

tgtgtgtgtg tgtgtatgtg tgtgtttctg agtaagtatt gactgggaaa aagagagaag     8160

tcaatcaaaa gtatactgtg caattgagag aggctggccc aagatttaaa acttcctgtg     8220

ggtaatctaa ctgtgagtag ataggaatcg gccatatgac gaaatgagat caataggaaa     8280

tgtgcttttt gaggaaattt tattttagta ccaaatgttg ccagtgacaa tcttcagtta     8340

agaagtaagt tattctgacc taaaattctt atctctgcca ctttggttta aaaacaaaaa     8400

cccttatata catggaatag ttatatttta attaagcatt tattttagtt gttttcatcc     8460

attcaagcaa aatgaataag cagcattttt cattgcactt aaaaatgtaa aatacctgca     8520

tgccactaat ctgtaacatt ttaccagttc agatgcctgt aatgtgtgac tttatgtgtg     8580

tctgtgttgt tttgaagaga ataaaggaaa taatactttg caaactgttt aaacaagtgt     8640

ttaaacttct attggcaaca tttattgggc taagcagtta ttgaaaactc cgcatagttt     8700

tattttccat ttgaaacttc aatcaaatca agactattat attcattagg gaattaaaga     8760

ctaatttgct ttttaaatgt gaagttgaac actgtgtgga aagtaaatgt gtgatgaagc     8820

aaaatgtata aagtatgaaa tattatactt ttaccctgga taattattca ggaccccagt     8880

tggcccaaat aggtgcaatt tttaatcctt tgaaattagc cagccagacc taatgctaag     8940

gtaaatgtaa actgttttaa ttaattaaga tctttctgct ttcgaaggta taatgtatct     9000

atttctgtca ggaatgatat ttccaaatga aaatgtaaag aacattggga aataataaac     9060

tttcctttca aagtaaaa                                                   9078


<210>  2014
<211>  2525
<212>  DNA
<213>  homo sapiens

<400>  2014
aaagtttccg agtccattcc gggagcggga gcccatcttg ctggctgccg aggccctcgc       60

tggaggagga gggtcagaac tcgggtgcag ccaatcgagg gcaacgctgc tacttatcag      120

agcagaatgg gctgtagttt agtgaaatag gaaagctgca aaacactgtg gagtgctccc      180

gtgtaaataa aaagaggaaa aaagtttctc aagtcgccgc tgcacgacgt ctggccggcg      240

ctggagcggg ggtctgcgct ctcccgagcg gccgcgcgct ggactttatt gtgccgcaac      300

cagccccagt tcccattgtt tgtgtttttt tcaaaatatg gcaaaggttc aggtgaacaa      360

tgtagtggtg ctggataacc cttctccttt ctacaacccg ttccagttcg agatcacctt      420

cgagtgcatc gaggacctgt ctgaagactt ggaatggaaa attatctatg tgggctctgc      480

agaaagtgaa gaatacgatc aagttttaga ctctgtttta gtgggtcctg ttcccgcagg      540

aaggcatatg tttgtatttc aggctgatgc acctaatcca ggactcattc cagatgcaga      600

tgcagtaggc gtaactgttg tgctaattac ttgtacctat cgaggacaag aatttattag      660

agttggctat tatgtaaata atgaatatac tgagacagaa ttaagggaaa atccaccagt      720

aaaaccagac ttttctaagc ttcaaaggaa tattttggca tctaatccca gggtcacaag      780

attccacatt aattgggaag ataacacaga aaaactggaa gatgcagaga gcagtaatcc      840

aaatctacag tcacttcttt caacagatgc attaccttca gcatcaaagg gatggtccac      900

atcagaaaac tcactaaatg tcatgttaga atcccacatg gactgcatgt gaccacctac      960

catcccttta gtacaaatta agctattaaa aatacacaga actatttccc tgaaattccg     1020

taagtacata gtcaaaacac aatgtgaaga atttgtttaa aaacatcctg tagaaagttt     1080

ataagaaaac cagtatttga acaaattgtg gaatataaat acaactattt ttaagtaatt     1140

tttttctcta atgtgttatt ttatttgttc tgaaactaat ctgattaaag catatatatt     1200

attttcttct cctttatatg taatgaaagc acttataaag aaacaggaat cattagacca     1260

ggttgtaaag atgtcttggc ctcccagaca gtctttggac cactatttta ctggcctttg     1320

aaagaacaaa gtttacttca actaaaatgt ttcttcctgt gaagacatat ggtatcattt     1380

taatttaagg ggcagatttc cattcttttt tggcatgtcc ttaaaaagag gatttgaaat     1440

caactatatg ctaccaagaa ctttaggatc caattttcca agccaccgtg aagcctctta     1500

tggctactat tatagttcat gagatgttgg acagcatttg gtttgtttgg taagagaaga     1560

acaaatatgg ctaattgtta ataaggtccc ctggctatgg tttttgttct tataacagag     1620

tttagaatat cagagcattt cttgaatcat acatcattat tgtccagtga attcaagacc     1680

aaatacaata tcgggagaaa atacaaactc cctgtgttta agaatagggg attacaatgg     1740

ctcaaattgg ttcatttgat ttctaaaaat accatgacct ttaaaaattc ttttaataga     1800

tcatgttatt ggcagtattt atataaaaac catggattta gaaaggtata tttagcttta     1860

ttataataga tacgttacta ttttggaaat atatatattt tcacacctgt agtactcttc     1920

cccatttcct ctgacactca tgcagaatga gatcaggcat atttgtggtt gacatactct     1980

agatagcttt tccaacaaat ctttgaaaag caatcttgga aaggaattca ttaactaaat     2040

ggggtaaaag gtttcttttt ctttgagagt taagtccttc ctcaaaaaat tttcttatgc     2100

tccataaaat tgaggtagaa tattttcatt attcttgcag ctaagcaaga cagccatatg     2160

atgcaggtta tgcagtgcct tcatatctaa aacttttata ctgcactttt taaagctttt     2220

atgttgagga aaggaaaagg gcatttgtct aaacatggat tctgagttgt atatatttcc     2280

tatcattcta aaaaagtgaa tttgtgaagc aaagttttgc cagatgttaa actttgaatt     2340

taatatacca gattattaaa atattgtcca ttaactagtt catagatttt aaaagtaaaa     2400

tacttctgac tgttaaaact atataaagaa aatctcattt gtctaattgc aattaaaaga     2460

aaaatgttaa aatattaaaa tgaaaataaa agcattactt tccaacaaaa aaaaaaaaaa     2520

aaaaa                                                                 2525


<210>  2015
<211>  10906
<212>  DNA
<213>  homo sapiens

<400>  2015
attggtggag gcggcaagtt taaacagagt caaaacgcca tacttgtttg gctcctcttt       60

ttaatttgcg agtttattgg gcttgttttc tgttttctag ggagtaggtt agtggaaaag      120

aaaaagggcc gaattcactc ccacgacctc tacagccgcc cctgagggga agcggtcagc      180

gtaagtcccg gatccccgct ccggagccgc ctcgtgggag cggggcaagg agatccagga      240

ggggtctcga atctgccatg gcgaaccggc gagtggggcg aggctgctgg gaagtgagcc      300

cgaccgagcg gaggccgccc gcggggctgc ggggccccgc ggccgaggag gaggcgtctt      360

ccccgccggt cctgtctctc agccacttct gcaggtctcc tttcctttgc ttcggggacg      420

ttctcctggg agcctcacgg acgctgtctc tggccctaga caaccctaac gaggaggtgg      480

cagaagtgaa gatctcccac ttcccggccg cggacctggg cttcagtgtg tcgcagcgct      540

gtttcgtgtt gcagcctaaa gagaaaattg ttatttctgt taactggaca ccactcaaag      600

aaggccgagt aagagagatt atgacatttc ttgtaaatga tgttctgaaa caccaagcta      660

tattactagg aaatgcagaa gagcagaaaa agaaaaagag gagtctttgg gataccatta      720

aaaagaagaa aatttcagcc tctacaagtc acaacagaag ggtttcaaat attcagaatg      780

ttaataaaac atttagtgtt tcccaaaaag ttgacagagt taggagccca ctacaagctt      840

gtgaaaactt ggctatgaat gaaggcggtc ccccaacaga aaacaattct ttaatacttg      900

aagaaaataa aatacccata tcacctatta gccctgcttt caatgaatgc catggtgcaa      960

cttgcttgcc actctctgta cgtcgatcta ctacctactc atctcttcat gcatcagaaa     1020

atagggaact attaaatgta cacagtgcca acgtttcaaa agtttctttt aatgagaaag     1080

ctgtaactga aacttccttt aattccgtaa atgttaatgg ccaaagagga gagaatagta     1140

aacttagtct tacccccaac tgttcttcaa ctttgaacat tacacaaagc caaatacatt     1200

ttctaagtcc agattctttt gtaaataata gtcatggagc taataatgaa ctagaattag     1260

taacatgtct ttcatcagat atgtttatga aagataattc acagcctgtg catttggaat     1320

caacaattgc acatgaaatt tatcagaaaa ttttaagtcc agattctttc ataaaagata     1380

attatggact aaatcaggat ctagaatcag agtcagttaa tcctatttta tcccctaatc     1440

aatttttaaa agataacatg gcatatatgt gtacatctca gcaaacatgt aaagtaccat     1500

tatcaaatga aaattctcaa gtcccacagt ctcctgaaga ttggagaaaa agtgaagttt     1560

cgccacgtat tcctgaatgt cagggttcaa aatctcccaa agctattttt gaagaactag     1620

tagaaatgaa gtcaaattac tacagtttta taaaacaaaa taatcctaaa ttttctgcag     1680

ttcaggatat ttctagtcat agccacaata aacaacctaa gagacgtcca atactttctg     1740

ccactgttac taaaaggaag gccacctgta ccagagaaaa ccaaactgag attaataaac     1800

caaaagcaaa aagatgtctc aacagtgcag tgggtgaaca tgaaaaagta ataaataatc     1860

aaaaggaaaa agaagatttt cattcttatc ttccaattat agatccaata ttaagtaaat     1920

ctaagagtta taaaaacgag gtaacaccct cttcgacaac agcttcagtt gctcggaaaa     1980

gaaagagcga tggaagcatg gaagatgcaa atgtgagagt tgcaattaca gaacatacag     2040

aagtgcgaga aatcaaaaga atccattttt ctccctcaga gcctaaaaca tcagctgtta     2100

agaaaacaaa aaatgtgaca acacccatct caaaacgtat tagcaacaga gagaaattaa     2160

acctgaagaa gaaaactgat ttatcaatat tcagaactcc aatttctaaa acaaacaaaa     2220

ggacaaaacc cattatcgct gtggcacagt ccagtttgac cttcataaaa ccattaaaaa     2280

cagatattcc cagacacccg atgccatttg ctgcaaaaaa catgttttat gatgaacgct     2340

ggaaggaaaa gcaggaacag ggcttcactt ggtggttaaa ttttatatta acccctgatg     2400

acttcactgt aaaaacaaat atttctgaag taaatgctgc tactcttctt ttgggaatag     2460

agaatcaaca taaaataagt gttcctagag cacctacaaa agaggaaatg tctctcagag     2520

cttatactgc tcggtgtagg ttaaacagac tacgtcgtgc agcatgccgt ttgtttactt     2580

ctgaaaaaat ggttaaagct attaaaaagc ttgaaattga aattgaagct aggcggttaa     2640

ttgttcgaaa agatagacac ctatggaaag atgtgggaga acgtcagaaa gtcctgaatt     2700

ggctgttgtc ctacaatcct ttgtggcttc gaattggtct agagacaact tatggagaac     2760

tcatatcttt ggaagataac agtgatgtca cagggttggc tatgtttatt ctgaatcgcc     2820

tactttggaa tcctgatata gcagctgagt atagacaccc cactgttcct cacctgtata     2880

gagatggtca tgaagaagct ttgtccaagt ttacattgaa aaagttattg ttgttggtct     2940

gttttcttga ttatgctaaa atttccagac tcattgatca tgatccttgt ctcttctgta     3000

aagatgccga attcaaggct agtaaagaaa tccttttggc tttttcacga gatttcctaa     3060

gtggtgaagg tgacctttcc cgtcaccttg gcttattggg attacctgtt aaccatgttc     3120

agacaccatt tgatgaattt gattttgccg ttacaaatct tgccgtagac ttgcaatgtg     3180

gagtgcgcct tgtgcgaacc atggaacttc tcacacagaa ctgggacctc tcaaagaaac     3240

tcaggattcc ggcaataagt cgtcttcaaa agatgcacaa tgttgacatt gttcttcaag     3300

ttcttaaatc acgaggaatt gaattaagtg atgagcatgg aaatacaatt ctatctaagg     3360

atattgtgga taggcacaga gaaaaaactc tcaggttgct ttggaaaata gcgtttgctt     3420

ttcaggtgga tatttccctt aacttagatc aattaaagga agaaattgcc tttctaaaac     3480

acacaaagag tataaagaaa acaatatctc tactatcatg ccattctgat gatcttatta     3540

ataagaaaaa aggcaaaagg gatagtggtt cctttgaaca atatagtgaa aacataaagt     3600

tattgatgga ttgggtaaat gctgtttgtg ccttctataa taaaaaggtg gagaatttta     3660

cagtgtcttt ctcagacggc cgtgtgttat gttacctgat ccaccattac catccttgct     3720

atgtgccatt tgacgctata tgtcagcgta ctactcaaac tgtggaatgt acgcaaactg     3780

gttcagtggt attaaattca tcatctgaat ctgatgacag ttctctggat atgtctctta     3840

aagcatttga tcatgaaaat acttcagagc tatacaaaga gctcctagaa aatgaaaaga     3900

aaaattttca cttggttagg tctgcagtta gagaccttgg tggaatacct gctatgatta     3960

atcattcaga tatgtcaaat acaattccag atgaaaaggt ggttattacc tatttgtcat     4020

ttctttgtgc aaggcttttg gatcttcgta aagaaataag agctgctcga ctcatacaaa     4080

caacatggag aaaatataaa ctaaaaacag atctcaaacg ccatcaggag agagagaaag     4140

ctgcaagaat tattcaattg gctgtaatca attttctagc aaaacaaaga ttgagaaaaa     4200

gagttaatgc agcactcgtc attcagaaat attggcgaag agtcttagca cagagaaaat     4260

tattaatgtt aaaaaaggaa aagctggaaa aagttcaaaa taaagcagca tcacttattc     4320

agggatattg gagaagatat tccactagac aaagatttct gaaattgaaa tattattcaa     4380

tcatcctgca atctaggata agaatgataa ttgctgttac atcttataaa cgatatcttt     4440

gggctacagt tacaattcag aggcattggc gtgcttattt aagaagaaaa caagatcaac     4500

aaagatatga aatgctaaaa tcatcaactc ttataatcca atctatgttc agaaaatgga     4560

agcaacgtaa aatgcaatca caagtaaaag ctacagtaat attgcaaaga gcttttagag     4620

aatggcattt aagaaaacaa gctaaagaag aaaattctgc tattatcata caatcatggt     4680

atagaatgca taaagaatta cggaaatata tttatattag atcttgtgtt gttatcattc     4740

agaaaagatt tcggtgcttt caagcccaaa agttatataa aagaagaaaa gagtccatac     4800

taaccatcca gaagtactac aaagcatatc tgaaaggaaa gattgagcgc accaactatt     4860

tgcagaaacg agctgcagcc attcaattac aagctgcttt taggagactg aaagctcata     4920

atttatgtag acaaattaga gctgcttgtg ttattcagtc atactggaga atgagacaag     4980

acagagttcg atttttaaac cttaagaaga ctattatcaa atttcaggca catgtaagaa     5040

aacatcaaca acgacagaaa tataagaaga tgaagaaagc agctgttata attcagactc     5100

atttccgagc ttatattttt gccatgaaag ttctagcatc ttaccagaaa acacgctctg     5160

ctgtcattgt gctgcagtct gcatatagag ggatgcaagc caggaaaatg tatattcaca     5220

tcctcacatc tgttataaag attcaatcat attatcgtgc ttatgtttct aaaaaggaat     5280

ttttgagcct aaaaaatgct acaataaaat tgcagtcaac tgttaagatg aaacaaacac     5340

gtaaacaata tttgcattta agagcagctg cactatttat ccagcaatgt taccgttcca     5400

aaaaaatagc tgcacaaaag agagaagagt atatgcagat gcgggaatct tgtatcaaac     5460

tgcaagcatt tgttagagga taccttgtcc gaaagcagat gaggttacaa agaaaagctg     5520

ttatttcact acagtcttat ttcagaatga gaaaggctcg gcagtattat ctgaaaatgt     5580

ataaagcaat tattgtcatt cagaattact atcatgcata caaagcacag gtcaatcaga     5640

ggaagaactt cttgcaagtc aaaaaagcag ctacttgctt gcaagcagct tacagaggtt     5700

ataaagtacg ccagctaatc aaacaacaat ctatagctgc tcttaaaatt cagtctgctt     5760

ttagaggcta taataaaagg gtaaaatatc aatctgtgct tcaatctata ataaagattc     5820

agagatggta cagggcgtac aagactcttc atgatacaag aacacatttt ttgaagacaa     5880

aggcagctgt gatttccctc cagtctgctt atcgtggctg gaaggttcgg aaacagatta     5940

gaagggaaca tcaagctgcc ttgaagattc agtctgcttt tagaatggcc aaggcccaga     6000

aacagtttag attgtttaaa acagcagcat tagtcatcca gcaaaatttc agagcatgga     6060

ctgcaggaag gaagcaatgt atggagtata ttgaactccg tcatgcggta ctggtgcttc     6120

aatctatgtg gaagggaaaa acactgagaa gacagcttca aaggcaacat aaatgtgcta     6180

tcatcataca gtcatactat agaatgcatg tgcaacaaaa gaagtggaaa atcatgaaaa     6240

aagctgctct tctgattcaa aagtattata gggcttacag tattggaaga gaacagaatc     6300

atttatattt gaaaacaaaa gcagctgtag taactttaca gtcagcttat cgtggtatga     6360

aagtgagaaa aagaataaag gattgcaaca aagcagcagt cactatacag tctaaataca     6420

gagcttacaa aaccaaaaag aaatatgcaa cctatagagc ttcagctatt ataattcaga     6480

gatggtatcg aggtattaaa attacaaacc atcagcataa ggagtatctt aatttgaaga     6540

agacagcaat taaaatccaa tctgtttata gaggtattag agttagaaga catattcaac     6600

acatgcacag ggcagccact tttattaaag ccatgtttaa aatgcatcag tcaagaataa     6660

gttaccatac aatgagaaaa gcagctattg ttattcaagt aagatgtaga gcatattatc     6720

aaggtaaaat gcagcgtgaa aagtacctga caattttgaa agctgttaaa gtccttcagg     6780

caagttttag aggagtaaga gttagacgga ctcttagaaa gatgcagact gcagcaacac     6840

tcattcagtc aaactacaga agatacagac agcaaacata ctttaataag ttaaagaaaa     6900

taacaaaaac agtacagcaa agatactggg caatgaaaga aagaaacata caatttcaaa     6960

ggtataacaa actgaggcat tctgtaatat acattcaggc tatttttagg ggaaagaaag     7020

ctagaagaca tttaaaaatg atgcatatag ccgcaactct cattcagagg agatttagaa     7080

ctctaatgat gagaagaaga ttcctctctc tcaagaaaac tgctattttg attcagagaa     7140

aatatcgggc acatctttgt acaaagcatc acttacagtt ccttcaggta caaaatgcag     7200

ttattaaaat ccagtcatca tacagaagat ggatgataag gaaaaggatg cgagagatgc     7260

acagggctgc tactttcatc cagtctactt tcagaatgca cagattacat atgagatatc     7320

aggctttgaa acaggcctcc gttgtgatcc aacagcaata ccaagcaaat agagctgcaa     7380

aactgcagag gcagcattat ctcagacaaa gacactctgc tgtgatcctt caggctgcat     7440

tcaggggtat gaaaactaga agacatttga agagtatgca ttcctctgca acccttattc     7500

agagtaggtt tagatcatta ctggtgagga gaagattcat ttccctcaaa aaagctacta     7560

tttttgttca gaggaaatat cgagccacca tttgtgccaa acataaattg taccaattct     7620

tgcacttaag aaaggcagcc attacaatac agtcatctta cagaagactg atggtaaaga     7680

agaagttaca agaaatgcaa agggctgcag ttctcattca ggctactttc aggatgtaca     7740

gaacatatat tacatttcag acttggaaac atgcttcaat tctaattcag caacattatc     7800

gaacatatag agctgcaaaa ttacaaagag aaaattatat cagacaatgg cattctgctg     7860

tggttattca ggctgcatat aaaggaatga aagcaagaca acttttaagg gaaaaacaca     7920

aagcttctat cgtaatacaa agcacctaca gaatgtatag gcagtattgt ttctaccaaa     7980

agcttcagtg ggctacaaaa atcatacaag aaaaatatag agcaaataaa aagaaacaga     8040

aagtatttca acacaatgaa cttaagaaag agacttgtgt tcaggcaggt tttcaggaca     8100

tgaacataaa aaaacagatt caggaacagc accaggctgc cattattatt cagaagcatt     8160

gtaaagcctt taaaataagg aagcattatc tccaccttag agcaacagta gtttctattc     8220

aaagaagata cagaaaacta actgcagtgc gtacccaagc agttatttgt atacagtctt     8280

attacagagg ctttaaagta cgaaaggata ttcaaaatat gcaccgggct gccacactaa     8340

ttcagtcatt ctatcgaatg cacagggcca aagttgatta tgaaacaaag aaaactgcaa     8400

ttgtggttat acagaattat tataggttgt atgttagagt aaaaacagaa agaaaaaact     8460

ttttagcagt tcagaaatct gtacgaacta ttcaggctgc ttttagaggc atgaaagtta     8520

gacaaaaatt gaaaaatgta tcagaggaaa agatggcagc cattgttaac caatctgcac     8580

tctgctgtta cagaagtaaa actcagtatg aagctgttca aagtgaaggt gttatgattc     8640

aagagtggta taaagcttct ggccttgctt gttcacagga agcagagtat cattctcaaa     8700

gtagggctgc agtaacaatt caaaaagctt tttgtagaat ggtcacaaga aaactggaaa     8760

cacagaaatg tgctgcccta cggattcagt tcttccttca gatggctgtg tatcggagaa     8820

gatttgttca gcagaaaaga gctgctatca ctttacagca ttattttagg acgtggcaaa     8880

ccagaaaaca gtttttacta tatagaaaag cagcagtggt tttacaaaat cactacagag     8940

catttctgtc tgcaaaacat caaagacaag tctatttaca gatcagaagc agtgttatca     9000

ttattcaagc tagaagtaaa ggatttatac agaaacggaa gtttcaggaa attaaaaata     9060

gcaccataaa aattcaggct atgtggagga gatatagagc caagaaatat ttatgtaaag     9120

tgaaagctgc ctgcaagatt caagcctggt atagatgttg gagagcacac aaagaatatc     9180

tagctatatt aaaagctgtt aaaattattc aaggttgctt ctataccaaa ctagagagaa     9240

cacggttttt gaatgtgaga gcatcagcaa ttatcattca gagaaaatgg agagctatac     9300

ttcctgcaaa gatagctcat gaacacttct taatgataaa aagacatcga gctgcttgtt     9360

tgatccaagc acattataga ggatataaag gaaggcaggt ctttcttcgg cagaaatctg     9420

ctgctttgat catacaaaaa tatatacgag ccagggaggc tggaaagcat gaaaggataa     9480

aatatattga atttaaaaaa tctacagtta tcctacaagc actggtgcgt ggttggctag     9540

tacgaaaaag atttttagaa cagagagcca aaattcgact tcttcacttc actgcagctg     9600

catattatca cctgaatgct gttagaattc aaagagccta taaactttac ctggctgtga     9660

agaatgctaa caagcaggtt aattcagtca tctgtattca gagatggttt cgagcaagat     9720

tacaagaaaa gagatttatt cagaaatatc atagcatcaa aaagattgag catgaaggtc     9780

aagaatgtct gagccagcga aatagggctg catcagtaat acagaaagca gtgcgccatt     9840

ttctcctccg taaaaagcag gaaaaattca ctagtggaat cattaaaatt caggcattat     9900

ggagaggcta ttcttggagg aagaaaaatg attgtacaaa aattaaagct atacgactaa     9960

gtcttcaagt tgttaatagg gagattcgag aagaaaacaa actctacaaa agaactgcac    10020

ttgcacttca ttaccttttg acatataagc acctttctgc cattcttgag gccttaaaac    10080

acctagaggt agttactaga ttgtctccac tttgttgtga gaacatggcc cagagtggag    10140

caatttctaa aatatttgtt ttgatccgaa gttgtaatcg cagtattcct tgtatggaag    10200

tcatcagata tgctgtgcaa gtcttgctta atgtatctaa gtatgagaaa actacttcag    10260

cagtttatga tgtagaaaat tgtatagata tactattgga gcttttgcag atataccgag    10320

aaaagcctgg taataaagtt gcagacaaag gcggaagcat ttttacaaaa acttgttgtt    10380

tgttggctat tttactgaag acaacaaata gagcctctga tgtacgaagt aggtccaaag    10440

ttgttgaccg tatttacagt ctctacaaac ttacagctca taaacataaa atgaatactg    10500

aaagaatact ttacaagcaa aagaagaatt cttctataag cattcctttt atcccagaaa    10560

cacctgtaag gaccagaata gtttcaagac ttaagccaga ttgggttttg agaagagata    10620

acatggaaga aatcacaaat cccctgcaag ctattcaaat ggtgatggat acgcttggca    10680

ttccttatta gtaaatgtaa acattttcag tatgtatagt gtaaagaaat attaaagcca    10740

atcatgagta cgtaaagtga tttttgctct ccgtgtacaa cttttaaaat ctgactttgt    10800

tttaaaaaaa cataaactgt tcattacatt cttcattttt atcatttata gttttatgca    10860

tgtaataaac taatatgtca taagatgaaa aaaaaaaaaa aaaaaa                   10906


<210>  2016
<211>  10906
<212>  DNA
<213>  homo sapiens

<400>  2016
attggtggag gcggcaagtt taaacagagt caaaacgcca tacttgtttg gctcctcttt       60

ttaatttgcg agtttattgg gcttgttttc tgttttctag ggagtaggtt agtggaaaag      120

aaaaagggcc gaattcactc ccacgacctc tacagccgcc cctgagggga agcggtcagc      180

gtaagtcccg gatccccgct ccggagccgc ctcgtgggag cggggcaagg agatccagga      240

ggggtctcga atctgccatg gcgaaccggc gagtggggcg aggctgctgg gaagtgagcc      300

cgaccgagcg gaggccgccc gcggggctgc ggggccccgc ggccgaggag gaggcgtctt      360

ccccgccggt cctgtctctc agccacttct gcaggtctcc tttcctttgc ttcggggacg      420

ttctcctggg agcctcacgg acgctgtctc tggccctaga caaccctaac gaggaggtgg      480

cagaagtgaa gatctcccac ttcccggccg cggacctggg cttcagtgtg tcgcagcgct      540

gtttcgtgtt gcagcctaaa gagaaaattg ttatttctgt taactggaca ccactcaaag      600

aaggccgagt aagagagatt atgacatttc ttgtaaatga tgttctgaaa caccaagcta      660

tattactagg aaatgcagaa gagcagaaaa agaaaaagag gagtctttgg gataccatta      720

aaaagaagaa aatttcagcc tctacaagtc acaacagaag ggtttcaaat attcagaatg      780

ttaataaaac atttagtgtt tcccaaaaag ttgacagagt taggagccca ctacaagctt      840

gtgaaaactt ggctatgaat gaaggcggtc ccccaacaga aaacaattct ttaatacttg      900

aagaaaataa aatacccata tcacctatta gccctgcttt caatgaatgc catggtgcaa      960

cttgcttgcc actctctgta cgtcgatcta ctacctactc atctcttcat gcatcagaaa     1020

atagggaact attaaatgta cacagtgcca acgtttcaaa agtttctttt aatgagaaag     1080

ctgtaactga aacttccttt aattccgtaa atgttaatgg ccaaagagga gagaatagta     1140

aacttagtct tacccccaac tgttcttcaa ctttgaacat tacacaaagc caaatacatt     1200

ttctaagtcc agattctttt gtaaataata gtcatggagc taataatgaa ctagaattag     1260

taacatgtct ttcatcagat atgtttatga aagataattc acagcctgtg catttggaat     1320

caacaattgc acatgaaatt tatcagaaaa ttttaagtcc agattctttc ataaaagata     1380

attatggact aaatcaggat ctagaatcag agtcagttaa tcctatttta tcccctaatc     1440

aatttttaaa agataacatg gcatatatgt gtacatctca gcaaacatgt aaagtaccat     1500

tatcaaatga aaattctcaa gtcccacagt ctcctgaaga ttggagaaaa agtgaagttt     1560

cgccacgtat tcctgaatgt cagggttcaa aatctcccaa agctattttt gaagaactag     1620

tagaaatgaa gtcaaattac tacagtttta taaaacaaaa taatcctaaa ttttctgcag     1680

ttcaggatat ttctagtcat agccacaata aacaacctaa gagacgtcca atactttctg     1740

ccactgttac taaaaggaag gccacctgta ccagagaaaa ccaaactgag attaataaac     1800

caaaagcaaa aagatgtctc aacagtgcag tgggtgaaca tgaaaaagta ataaataatc     1860

aaaaggaaaa agaagatttt cattcttatc ttccaattat agatccaata ttaagtaaat     1920

ctaagagtta taaaaacgag gtaacaccct cttcgacaac agcttcagtt gctcggaaaa     1980

gaaagagcga tggaagcatg gaagatgcaa atgtgagagt tgcaattaca gaacatacag     2040

aagtgcgaga aatcaaaaga atccattttt ctccctcaga gcctaaaaca tcagctgtta     2100

agaaaacaaa aaatgtgaca acacccatct caaaacgtat tagcaacaga gagaaattaa     2160

acctgaagaa gaaaactgat ttatcaatat tcagaactcc aatttctaaa acaaacaaaa     2220

ggacaaaacc cattatcgct gtggcacagt ccagtttgac cttcataaaa ccattaaaaa     2280

cagatattcc cagacacccg atgccatttg ctgcaaaaaa catgttttat gatgaacgct     2340

ggaaggaaaa gcaggaacag ggcttcactt ggtggttaaa ttttatatta acccctgatg     2400

acttcactgt aaaaacaaat atttctgaag taaatgctgc tactcttctt ttgggaatag     2460

agaatcaaca taaaataagt gttcctagag cacctacaaa agaggaaatg tctctcagag     2520

cttatactgc tcggtgtagg ttaaacagac tacgtcgtgc agcatgccgt ttgtttactt     2580

ctgaaaaaat ggttaaagct attaaaaagc ttgaaattga aattgaagct aggcggttaa     2640

ttgttcgaaa agatagacac ctatggaaag atgtgggaga acgtcagaaa gtcctgaatt     2700

ggctgttgtc ctacaatcct ttgtggcttc gaattggtct agagacaact tatggagaac     2760

tcatatcttt ggaagataac agtgatgtca cagggttggc tatgtttatt ctgaatcgcc     2820

tactttggaa tcctgatata gcagctgagt atagacaccc cactgttcct cacctgtata     2880

gagatggtca tgaagaagct ttgtccaagt ttacattgaa aaagttattg ttgttggtct     2940

gttttcttga ttatgctaaa atttccagac tcattgatca tgatccttgt ctcttctgta     3000

aagatgccga attcaaggct agtaaagaaa tccttttggc tttttcacga gatttcctaa     3060

gtggtgaagg tgacctttcc cgtcaccttg gcttattggg attacctgtt aaccatgttc     3120

agacaccatt tgatgaattt gattttgccg ttacaaatct tgccgtagac ttgcaatgtg     3180

gagtgcgcct tgtgcgaacc atggaacttc tcacacagaa ctgggacctc tcaaagaaac     3240

tcaggattcc ggcaataagt cgtcttcaaa agatgcacaa tgttgacatt gttcttcaag     3300

ttcttaaatc acgaggaatt gaattaagtg atgagcatgg aaatacaatt ctatctaagg     3360

atattgtgga taggcacaga gaaaaaactc tcaggttgct ttggaaaata gcgtttgctt     3420

ttcaggtgga tatttccctt aacttagatc aattaaagga agaaattgcc tttctaaaac     3480

acacaaagag tataaagaaa acaatatctc tactatcatg ccattctgat gatcttatta     3540

ataagaaaaa aggcaaaagg gatagtggtt cctttgaaca atatagtgaa aacataaagt     3600

tattgatgga ttgggtaaat gctgtttgtg ccttctataa taaaaaggtg gagaatttta     3660

cagtgtcttt ctcagacggc cgtgtgttat gttacctgat ccaccattac catccttgct     3720

atgtgccatt tgacgctata tgtcagcgta ctactcaaac tgtggaatgt acgcaaactg     3780

gttcagtggt attaaattca tcatctgaat ctgatgacag ttctctggat atgtctctta     3840

aagcatttga tcatgaaaat acttcagagc tatacaaaga gctcctagaa aatgaaaaga     3900

aaaattttca cttggttagg tctgcagtta gagaccttgg tggaatacct gctatgatta     3960

atcattcaga tatgtcaaat acaattccag atgaaaaggt ggttattacc tatttgtcat     4020

ttctttgtgc aaggcttttg gatcttcgta aagaaataag agctgctcga ctcatacaaa     4080

caacatggag aaaatataaa ctaaaaacag atctcaaacg ccatcaggag agagagaaag     4140

ctgcaagaat tattcaattg gctgtaatca attttctagc aaaacaaaga ttgagaaaaa     4200

gagttaatgc agcactcgtc attcagaaat attggcgaag agtcttagca cagagaaaat     4260

tattaatgtt aaaaaaggaa aagctggaaa aagttcaaaa taaagcagca tcacttattc     4320

agggatattg gagaagatat tccactagac aaagatttct gaaattgaaa tattattcaa     4380

tcatcctgca atctaggata agaatgataa ttgctgttac atcttataaa cgatatcttt     4440

gggctacagt tacaattcag aggcattggc gtgcttattt aagaagaaaa caagatcaac     4500

aaagatatga aatgctaaaa tcatcaactc ttataatcca atctatgttc agaaaatgga     4560

agcaacgtaa aatgcaatca caagtaaaag ctacagtaat attgcaaaga gcttttagag     4620

aatggcattt aagaaaacaa gctaaagaag aaaattctgc tattatcata caatcatggt     4680

atagaatgca taaagaatta cggaaatata tttatattag atcttgtgtt gttatcattc     4740

agaaaagatt tcggtgcttt caagcccaaa agttatataa aagaagaaaa gagtccatac     4800

taaccatcca gaagtactac aaagcatatc tgaaaggaaa gattgagcgc accaactatt     4860

tgcagaaacg agctgcagcc attcaattac aagctgcttt taggagactg aaagctcata     4920

atttatgtag acaaattaga gctgcttgtg ttattcagtc atactggaga atgagacaag     4980

acagagttcg atttttaaac cttaagaaga ctattatcaa atttcaggca catgtaagaa     5040

aacatcaaca acgacagaaa tataagaaga tgaagaaagc agctgttata attcagactc     5100

atttccgagc ttatattttt gccatgaaag ttctagcatc ttaccagaaa acacgctctg     5160

ctgtcattgt gctgcagtct gcatatagag ggatgcaagc caggaaaatg tatattcaca     5220

tcctcacatc tgttataaag attcaatcat attatcgtgc ttatgtttct aaaaaggaat     5280

ttttgagcct aaaaaatgct acaataaaat tgcagtcaac tgttaagatg aaacaaacac     5340

gtaaacaata tttgcattta agagcagctg cactatttat ccagcaatgt taccgttcca     5400

aaaaaatagc tgcacaaaag agagaagagt atatgcagat gcgggaatct tgtatcaaac     5460

tgcaagcatt tgttagagga taccttgtcc gaaagcagat gaggttacaa agaaaagctg     5520

ttatttcact acagtcttat ttcagaatga gaaaggctcg gcagtattat ctgaaaatgt     5580

ataaagcaat tattgtcatt cagaattact atcatgcata caaagcacag gtcaatcaga     5640

ggaagaactt cttgcaagtc aaaaaagcag ctacttgctt gcaagcagct tacagaggtt     5700

ataaagtacg ccagctaatc aaacaacaat ctatagctgc tcttaaaatt cagtctgctt     5760

ttagaggcta taataaaagg gtaaaatatc aatctgtgct tcaatctata ataaagattc     5820

agagatggta cagggcgtac aagactcttc atgatacaag aacacatttt ttgaagacaa     5880

aggcagctgt gatttccctc cagtctgctt atcgtggctg gaaggttcgg aaacagatta     5940

gaagggaaca tcaagctgcc ttgaagattc agtctgcttt tagaatggcc aaggcccaga     6000

aacagtttag attgtttaaa acagcagcat tagtcatcca gcaaaatttc agagcatgga     6060

ctgcaggaag gaagcaatgt atggagtata ttgaactccg tcatgcggta ctggtgcttc     6120

aatctatgtg gaagggaaaa acactgagaa gacagcttca aaggcaacat aaatgtgcta     6180

tcatcataca gtcatactat agaatgcatg tgcaacaaaa gaagtggaaa atcatgaaaa     6240

aagctgctct tctgattcaa aagtattata gggcttacag tattggaaga gaacagaatc     6300

atttatattt gaaaacaaaa gcagctgtag taactttaca gtcagcttat cgtggtatga     6360

aagtgagaaa aagaataaag gattgcaaca aagcagcagt cactatacag tctaaataca     6420

gagcttacaa aaccaaaaag aaatatgcaa cctatagagc ttcagctatt ataattcaga     6480

gatggtatcg aggtattaaa attacaaacc atcagcataa ggagtatctt aatttgaaga     6540

agacagcaat taaaatccaa tctgtttata gaggtattag agttagaaga catattcaac     6600

acatgcacag ggcagccact tttattaaag ccatgtttaa aatgcatcag tcaagaataa     6660

gttaccatac aatgagaaaa gcagctattg ttattcaagt aagatgtaga gcatattatc     6720

aaggtaaaat gcagcgtgaa aagtacctga caattttgaa agctgttaaa gtccttcagg     6780

caagttttag aggagtaaga gttagacgga ctcttagaaa gatgcagact gcagcaacac     6840

tcattcagtc aaactacaga agatacagac agcaaacata ctttaataag ttaaagaaaa     6900

taacaaaaac agtacagcaa agatactggg caatgaaaga aagaaacata caatttcaaa     6960

ggtataacaa actgaggcat tctgtaatat acattcaggc tatttttagg ggaaagaaag     7020

ctagaagaca tttaaaaatg atgcatatag ccgcaactct cattcagagg agatttagaa     7080

ctctaatgat gagaagaaga ttcctctctc tcaagaaaac tgctattttg attcagagaa     7140

aatatcgggc acatctttgt acaaagcatc acttacagtt ccttcaggta caaaatgcag     7200

ttattaaaat ccagtcatca tacagaagat ggatgataag gaaaaggatg cgagagatgc     7260

acagggctgc tactttcatc cagtctactt tcagaatgca cagattacat atgagatatc     7320

aggctttgaa acaggcctcc gttgtgatcc aacagcaata ccaagcaaat agagctgcaa     7380

aactgcagag gcagcattat ctcagacaaa gacactctgc tgtgatcctt caggctgcat     7440

tcaggggtat gaaaactaga agacatttga agagtatgca ttcctctgca acccttattc     7500

agagtaggtt tagatcatta ctggtgagga gaagattcat ttccctcaaa aaagctacta     7560

tttttgttca gaggaaatat cgagccacca tttgtgccaa acataaattg taccaattct     7620

tgcacttaag aaaggcagcc attacaatac agtcatctta cagaagactg atggtaaaga     7680

agaagttaca agaaatgcaa agggctgcag ttctcattca ggctactttc aggatgtaca     7740

gaacatatat tacatttcag acttggaaac atgcttcaat tctaattcag caacattatc     7800

gaacatatag agctgcaaaa ttacaaagag aaaattatat cagacaatgg cattctgctg     7860

tggttattca ggctgcatat aaaggaatga aagcaagaca acttttaagg gaaaaacaca     7920

aagcttctat cgtaatacaa agcacctaca gaatgtatag gcagtattgt ttctaccaaa     7980

agcttcagtg ggctacaaaa atcatacaag aaaaatatag agcaaataaa aagaaacaga     8040

aagtatttca acacaatgaa cttaagaaag agacttgtgt tcaggcaggt tttcaggaca     8100

tgaacataaa aaaacagatt caggaacagc accaggctgc cattattatt cagaagcatt     8160

gtaaagcctt taaaataagg aagcattatc tccaccttag agcaacagta gtttctattc     8220

aaagaagata cagaaaacta actgcagtgc gtacccaagc agttatttgt atacagtctt     8280

attacagagg ctttaaagta cgaaaggata ttcaaaatat gcaccgggct gccacactaa     8340

ttcagtcatt ctatcgaatg cacagggcca aagttgatta tgaaacaaag aaaactgcaa     8400

ttgtggttat acagaattat tataggttgt atgttagagt aaaaacagaa agaaaaaact     8460

ttttagcagt tcagaaatct gtacgaacta ttcaggctgc ttttagaggc atgaaagtta     8520

gacaaaaatt gaaaaatgta tcagaggaaa agatggcagc cattgttaac caatctgcac     8580

tctgctgtta cagaagtaaa actcagtatg aagctgttca aagtgaaggt gttatgattc     8640

aagagtggta taaagcttct ggccttgctt gttcacagga agcagagtat cattctcaaa     8700

gtagggctgc agtaacaatt caaaaagctt tttgtagaat ggtcacaaga aaactggaaa     8760

cacagaaatg tgctgcccta cggattcagt tcttccttca gatggctgtg tatcggagaa     8820

gatttgttca gcagaaaaga gctgctatca ctttacagca ttattttagg acgtggcaaa     8880

ccagaaaaca gtttttacta tatagaaaag cagcagtggt tttacaaaat cactacagag     8940

catttctgtc tgcaaaacat caaagacaag tctatttaca gatcagaagc agtgttatca     9000

ttattcaagc tagaagtaaa ggatttatac agaaacggaa gtttcaggaa attaaaaata     9060

gcaccataaa aattcaggct atgtggagga gatatagagc caagaaatat ttatgtaaag     9120

tgaaagctgc ctgcaagatt caagcctggt atagatgttg gagagcacac aaagaatatc     9180

tagctatatt aaaagctgtt aaaattattc aaggttgctt ctataccaaa ctagagagaa     9240

cacggttttt gaatgtgaga gcatcagcaa ttatcattca gagaaaatgg agagctatac     9300

ttcctgcaaa gatagctcat gaacacttct taatgataaa aagacatcga gctgcttgtt     9360

tgatccaagc acattataga ggatataaag gaaggcaggt ctttcttcgg cagaaatctg     9420

ctgctttgat catacaaaaa tatatacgag ccagggaggc tggaaagcat gaaaggataa     9480

aatatattga atttaaaaaa tctacagtta tcctacaagc actggtgcgt ggttggctag     9540

tacgaaaaag atttttagaa cagagagcca aaattcgact tcttcacttc actgcagctg     9600

catattatca cctgaatgct gttagaattc aaagagccta taaactttac ctggctgtga     9660

agaatgctaa caagcaggtt aattcagtca tctgtattca gagatggttt cgagcaagat     9720

tacaagaaaa gagatttatt cagaaatatc atagcatcaa aaagattgag catgaaggtc     9780

aagaatgtct gagccagcga aatagggctg catcagtaat acagaaagca gtgcgccatt     9840

ttctcctccg taaaaagcag gaaaaattca ctagtggaat cattaaaatt caggcattat     9900

ggagaggcta ttcttggagg aagaaaaatg attgtacaaa aattaaagct atacgactaa     9960

gtcttcaagt tgttaatagg gagattcgag aagaaaacaa actctacaaa agaactgcac    10020

ttgcacttca ttaccttttg acatataagc acctttctgc cattcttgag gccttaaaac    10080

acctagaggt agttactaga ttgtctccac tttgttgtga gaacatggcc cagagtggag    10140

caatttctaa aatatttgtt ttgatccgaa gttgtaatcg cagtattcct tgtatggaag    10200

tcatcagata tgctgtgcaa gtcttgctta atgtatctaa gtatgagaaa actacttcag    10260

cagtttatga tgtagaaaat tgtatagata tactattgga gcttttgcag atataccgag    10320

aaaagcctgg taataaagtt gcagacaaag gcggaagcat ttttacaaaa acttgttgtt    10380

tgttggctat tttactgaag acaacaaata gagcctctga tgtacgaagt aggtccaaag    10440

ttgttgaccg tatttacagt ctctacaaac ttacagctca taaacataaa atgaatactg    10500

aaagaatact ttacaagcaa aagaagaatt cttctataag cattcctttt atcccagaaa    10560

cacctgtaag gaccagaata gtttcaagac ttaagccaga ttgggttttg agaagagata    10620

acatggaaga aatcacaaat cccctgcaag ctattcaaat ggtgatggat acgcttggca    10680

ttccttatta gtaaatgtaa acattttcag tatgtatagt gtaaagaaat attaaagcca    10740

atcatgagta cgtaaagtga tttttgctct ccgtgtacaa cttttaaaat ctgactttgt    10800

tttaaaaaaa cataaactgt tcattacatt cttcattttt atcatttata gttttatgca    10860

tgtaataaac taatatgtca taagatgaaa aaaaaaaaaa aaaaaa                   10906


<210>  2017
<211>  5580
<212>  DNA
<213>  homo sapiens

<400>  2017
cgcggagctt gtggcgccag aattcggagc gcggaagagc cagagctgcg agcgcctgga       60

gctggatctc tctccggtcg cgcacgccga ggccagtagg gagagaagat ggtggttctc      120

cgcagcagct tggagctgca caaccactcc gcggcctcgg ccacgggctc cttggacctg      180

tccagtgact tcctcagtct ggagcacatc ggccggaggc ggctccgctc ggccggcgcg      240

gcgcagaaga aacccgcggc gaccacagcc aaagcgggcg atgggtcatc agttaaggaa      300

gttgaaacct accaccggac acgtgcttta agatctttga gaaaagatgc acagaattct      360

tcagattcta gttttgagaa gaatgtggaa ataacggagc aacttgctaa tggcaggcat      420

tttacaaggc agttggccag acagcaggct gataaaaaaa aagaagagca cagagaagac      480

aaagtgattc cagttactcg gtcattgagg gctagaaaca tcgttcaaag tacagaacac      540

ttacatgaag ataatggtga tgttgaagtg cgtcgaagtt gtaggattag aagtcgttat      600

agtggtgtaa accagtccat gctgtttgac aaacttataa ctaacactgc tgaagctgta      660

cttcaaaaaa tggatgacat gaagaagatg cgtagacagc gaatgagaga acttgaagac      720

ttgggagtgt ttaatgaaac agaagaaagc aatcttaata tgtacacaag aggaaaacag      780

aaagatattc aaagaactga tgaagaaaca actgataatc aagaaggcag tgtggagtca      840

tctgaagagg gtgaagacca agaacatgaa gatgatggtg aagatgaaga tgatgaagat      900

gatgatgatg atgacgatga tgatgatgat gatgatgatg aagatgatga agatgaagaa      960

gatggagaag aagagaatca gaagcgatat tatcttagac agagaaaagc tactgtttac     1020

tatcaggctc cattggaaaa acctcgtcac cagagaaagc ccaacatatt ttatagtggc     1080

ccagcttctc ctgcaagacc aagataccga ttatcttccg caggaccaag aagtccttac     1140

tgtaaacgaa tgaacaggcg aaggcatgca atccacagta gtgactcgac ttcatcttcc     1200

tcctctgaag atgaacagca ctttgagagg cggaggaaaa ggagtcgtaa tagggctatc     1260

aataggtgcc tcccactaaa ttttcggaaa gatgaattaa aaggcattta taaagatcga     1320

atgaaaattg gagcaagcct tgccgatgtt gatccaatgc aactagattc ttcagtacga     1380

tttgatagtg ttggtggcct gtctaatcat atagcagctc taaaagagat ggtggtgttt     1440

ccattacttt atccagaagt ctttgaaaaa tttaaaattc aacccccaag aggttgtttg     1500

ttttatgggc cacctggaac tggaaagact ctggttgcca gagcacttgc caatgagtgc     1560

agtcaagggg ataaaagagt agcatttttc atgaggaaag gtgctgattg tctaagtaaa     1620

tgggtaggag aatctgaaag acagctacga ttgctgtttg atcaggccta tcagatgcgc     1680

ccatcaatta ttttttttga cgaaattgat ggtctggctc cagtacggtc aagcaggcaa     1740

gatcagattc acagttctat tgtttccacc ctgctagctc ttatggatgg attggacagc     1800

agaggggaaa ttgtggtcat tggtgctacg aacaggctag attctataga tcctgcttta     1860

cgaaggcctg gtcgctttga tagagaattc ctctttagcc tgcctgataa agaggctcga     1920

aaagagattc taaagattca caccagggat tggaatccca aaccactgga cacattttta     1980

gaagagctag cagaaaactg tgttggatac tgtggagcag atattaaatc aatatgtgct     2040

gaagctgctt tatgtgcttt acgacgacgc tacccacaga tctataccac tagtgagaaa     2100

ctgcagttgg atctctcttc aattaatatc tcagctaagg atttcgaggt agctatgcaa     2160

aagatgatac cagcctccca aagagctgtg acatcacctg ggcaggcact gtccaccgtt     2220

gtgaaaccac tcctgcaaaa cactgttgac aagattttag aagccctgca gagagtattt     2280

ccacatgcag aattcagaac aaataaaaca ttagactcag atatttcttg tcctctgcta     2340

gaaagtgact tggcttacag tgatgatgat gttccatcag tttatgaaaa tggactttct     2400

cagaaatctt ctcataaggc aaaagacaat tttaattttc ttcatttgaa tagaaatgct     2460

tgttaccaac ctatgtcttt tcgaccaaga atattgatag taggagaacc aggatttggg     2520

caaggttctc acttggcacc agctgtcatt catgctttgg aaaagtttac tgtatataca     2580

ttagacattc ctgttctttt tggagttagt actacatccc ctgaagaaac atgtgcccag     2640

gtgattcgtg aagctaagag aacagcacca agtatagtgt atgttcctca tatccacgtg     2700

tggtgggaaa tagttggacc gacacttaaa gccacattta ccacattatt acagaatatt     2760

ccttcatttg ctccagtttt actacttgca acttctgaca aaccccattc cgctttgcca     2820

gaagaggtgc aagaattgtt tatccgtgat tatggagaga tttttaatgt ccagttaccg     2880

gataaagaag aacggacaaa attttttgaa gatttaattc taaaacaagc tgctaagcct     2940

cctatatcaa aaaagaaagc agttttgcag gctttggagg tactcccagt agcaccacca     3000

cctgagccaa gatcactgac agcagaagaa gtgaaacgac tagaagaaca agaagaagat     3060

acatttagag aactgaggat tttcttaaga aatgttacac ataggcttgc tattgacaag     3120

cgattccgag tgtttactaa gcctgttgac cctgatgagg ttcctgatta tgtcactgta     3180

ataaagcaac caatggacct ttcatctgta atcagtaaaa ttgatctaca caagtatctg     3240

actgtgaaag actatttgag agatattgat ctaatctgta gtaatgcctt agaatacaat     3300

ccagatagag atcctggaga tcgtcttatt aggcatagag cctgtgcttt aagagatact     3360

gcctatgcca taattaaaga agaacttgat gaagactttg agcagctctg tgaagaaatt     3420

caggaatcta gaaagaaaag aggttgtagc tcctccaaat atgccccgtc ttactaccat     3480

gtgatgccaa agcaaaattc cactcttgtt ggtgataaaa gatcagaccc agagcagaat     3540

gaaaagctaa agacaccgag tactcctgtg gcttgcagca ctcctgctca gttgaagagg     3600

aaaattcgca aaaagtcaaa ctggtactta ggcaccataa aaaagcgaag gaagatttca     3660

caggcaaagg atgatagcca gaatgccata gatcacaaaa ttgagagtga tacagaggaa     3720

actcaagaca caagtgtaga tcataatgag accggaaaca caggagagtc ttcggtggaa     3780

gaaaatgaaa aacagcaaaa tgcctctgaa agcaaactgg aattgagaaa taattcaaat     3840

acttgtaata tagagaatga gcttgaagac tctaggaaga ctacagcatg tacagaattg     3900

agagacaaga ttgcttgtaa tggagatgct tctagctctc agataataca tatttctgat     3960

gaaaatgaag gaaaagaaat gtgtgttctg cgaatgactc gagctagacg ttcccaggta     4020

gaacagcagc agctcatcac tgttgaaaag gctttggcaa ttctttctca gcctacaccc     4080

tcacttgttg tggatcatga gcgattaaaa aatcttttga agactgttgt taaaaaaagt     4140

caaaactaca acatatttca gttggaaaat ttgtatgcag taatcagcca atgtatttat     4200

cggcatcgca aggaccatga taaaacatca cttattcaga aaatggagca agaggtagaa     4260

aacttcagtt gttccagatg atgatgtcat ggtatcgagt attctttata ttcagttcct     4320

atttaagtca tttttgtcat gtccgcctaa ttgatgtagt atgaaaccct gcatctttaa     4380

ggaaaagatt aaaatagtaa aataaaagta tttaaacttt cctgatattt atgtacatat     4440

taagataaat gtcatgtgta agataactga taaatattgg aactttgcta gaacaagacc     4500

ctgtagtaat agtaataata gttgaagttt ggccaactct taataaagtt attttggtaa     4560

ctaatgtttt atggcactta agaataatta gcagcgttaa attttgtttg tattaagcac     4620

ttttaatttt atccttccta aaaatagttt attgtatctg acaagaaact tacttaacca     4680

ttgtgtcctt cccatctttt ttgtcatctt tgttttcttc aaatgccctc ctcccatctg     4740

ccttgagatt ccctcgtctt cacttaaaag ccagagtgca agtcatgatt tgcgggaggg     4800

ctcttgaacc acttctggct gcaccacaat tctgtacttg agtatcacag tcattgtttt     4860

tgagacaaac atttttataa ttctaatttg ggttaataaa gattttaaat atttcttggt     4920

ttacttttgt aattatatac acaacaaatg tattaataac taccttgtta aacacctttt     4980

aatagcacaa ggtttttata tttgcaagct gttgatatct ttctaaaact gtttaggtta     5040

tagtctattg atacttttta tatacaattt tataaatata aatattataa ttttatatta     5100

atggtaccaa aaatacattt cttaaggtta aaagcatgca cttccatgca tacttgcttt     5160

tggggagagt ggggagaaga cattctaata atcagtttgt gaaatagctt ctgttggaaa     5220

ccttttgagg ggaataagga atggtcatct aaaatgagag attctggatt ttaatgcagt     5280

tcaaagttga gctgtatttt tgttgttgat ttatctggat tttttttaaa gccttctaaa     5340

acccagtgaa ttcaatacct taattagtac atactatctt atgtaatgca taaagcaatg     5400

ccagtcactg agaacattta aatatattta tattcctgga gatacacatt ctcatttttg     5460

ttggtttatt ataaattatt cttctagatg catcttttat aactaggatt tcattttgtg     5520

tgtatagctt atgtaataaa ttttaaaggt gaaaactctc ttaaaaaaaa aaaaaaaaaa     5580


<210>  2018
<211>  5580
<212>  DNA
<213>  homo sapiens

<400>  2018
cgcggagctt gtggcgccag aattcggagc gcggaagagc cagagctgcg agcgcctgga       60

gctggatctc tctccggtcg cgcacgccga ggccagtagg gagagaagat ggtggttctc      120

cgcagcagct tggagctgca caaccactcc gcggcctcgg ccacgggctc cttggacctg      180

tccagtgact tcctcagtct ggagcacatc ggccggaggc ggctccgctc ggccggcgcg      240

gcgcagaaga aacccgcggc gaccacagcc aaagcgggcg atgggtcatc agttaaggaa      300

gttgaaacct accaccggac acgtgcttta agatctttga gaaaagatgc acagaattct      360

tcagattcta gttttgagaa gaatgtggaa ataacggagc aacttgctaa tggcaggcat      420

tttacaaggc agttggccag acagcaggct gataaaaaaa aagaagagca cagagaagac      480

aaagtgattc cagttactcg gtcattgagg gctagaaaca tcgttcaaag tacagaacac      540

ttacatgaag ataatggtga tgttgaagtg cgtcgaagtt gtaggattag aagtcgttat      600

agtggtgtaa accagtccat gctgtttgac aaacttataa ctaacactgc tgaagctgta      660

cttcaaaaaa tggatgacat gaagaagatg cgtagacagc gaatgagaga acttgaagac      720

ttgggagtgt ttaatgaaac agaagaaagc aatcttaata tgtacacaag aggaaaacag      780

aaagatattc aaagaactga tgaagaaaca actgataatc aagaaggcag tgtggagtca      840

tctgaagagg gtgaagacca agaacatgaa gatgatggtg aagatgaaga tgatgaagat      900

gatgatgatg atgacgatga tgatgatgat gatgatgatg aagatgatga agatgaagaa      960

gatggagaag aagagaatca gaagcgatat tatcttagac agagaaaagc tactgtttac     1020

tatcaggctc cattggaaaa acctcgtcac cagagaaagc ccaacatatt ttatagtggc     1080

ccagcttctc ctgcaagacc aagataccga ttatcttccg caggaccaag aagtccttac     1140

tgtaaacgaa tgaacaggcg aaggcatgca atccacagta gtgactcgac ttcatcttcc     1200

tcctctgaag atgaacagca ctttgagagg cggaggaaaa ggagtcgtaa tagggctatc     1260

aataggtgcc tcccactaaa ttttcggaaa gatgaattaa aaggcattta taaagatcga     1320

atgaaaattg gagcaagcct tgccgatgtt gatccaatgc aactagattc ttcagtacga     1380

tttgatagtg ttggtggcct gtctaatcat atagcagctc taaaagagat ggtggtgttt     1440

ccattacttt atccagaagt ctttgaaaaa tttaaaattc aacccccaag aggttgtttg     1500

ttttatgggc cacctggaac tggaaagact ctggttgcca gagcacttgc caatgagtgc     1560

agtcaagggg ataaaagagt agcatttttc atgaggaaag gtgctgattg tctaagtaaa     1620

tgggtaggag aatctgaaag acagctacga ttgctgtttg atcaggccta tcagatgcgc     1680

ccatcaatta ttttttttga cgaaattgat ggtctggctc cagtacggtc aagcaggcaa     1740

gatcagattc acagttctat tgtttccacc ctgctagctc ttatggatgg attggacagc     1800

agaggggaaa ttgtggtcat tggtgctacg aacaggctag attctataga tcctgcttta     1860

cgaaggcctg gtcgctttga tagagaattc ctctttagcc tgcctgataa agaggctcga     1920

aaagagattc taaagattca caccagggat tggaatccca aaccactgga cacattttta     1980

gaagagctag cagaaaactg tgttggatac tgtggagcag atattaaatc aatatgtgct     2040

gaagctgctt tatgtgcttt acgacgacgc tacccacaga tctataccac tagtgagaaa     2100

ctgcagttgg atctctcttc aattaatatc tcagctaagg atttcgaggt agctatgcaa     2160

aagatgatac cagcctccca aagagctgtg acatcacctg ggcaggcact gtccaccgtt     2220

gtgaaaccac tcctgcaaaa cactgttgac aagattttag aagccctgca gagagtattt     2280

ccacatgcag aattcagaac aaataaaaca ttagactcag atatttcttg tcctctgcta     2340

gaaagtgact tggcttacag tgatgatgat gttccatcag tttatgaaaa tggactttct     2400

cagaaatctt ctcataaggc aaaagacaat tttaattttc ttcatttgaa tagaaatgct     2460

tgttaccaac ctatgtcttt tcgaccaaga atattgatag taggagaacc aggatttggg     2520

caaggttctc acttggcacc agctgtcatt catgctttgg aaaagtttac tgtatataca     2580

ttagacattc ctgttctttt tggagttagt actacatccc ctgaagaaac atgtgcccag     2640

gtgattcgtg aagctaagag aacagcacca agtatagtgt atgttcctca tatccacgtg     2700

tggtgggaaa tagttggacc gacacttaaa gccacattta ccacattatt acagaatatt     2760

ccttcatttg ctccagtttt actacttgca acttctgaca aaccccattc cgctttgcca     2820

gaagaggtgc aagaattgtt tatccgtgat tatggagaga tttttaatgt ccagttaccg     2880

gataaagaag aacggacaaa attttttgaa gatttaattc taaaacaagc tgctaagcct     2940

cctatatcaa aaaagaaagc agttttgcag gctttggagg tactcccagt agcaccacca     3000

cctgagccaa gatcactgac agcagaagaa gtgaaacgac tagaagaaca agaagaagat     3060

acatttagag aactgaggat tttcttaaga aatgttacac ataggcttgc tattgacaag     3120

cgattccgag tgtttactaa gcctgttgac cctgatgagg ttcctgatta tgtcactgta     3180

ataaagcaac caatggacct ttcatctgta atcagtaaaa ttgatctaca caagtatctg     3240

actgtgaaag actatttgag agatattgat ctaatctgta gtaatgcctt agaatacaat     3300

ccagatagag atcctggaga tcgtcttatt aggcatagag cctgtgcttt aagagatact     3360

gcctatgcca taattaaaga agaacttgat gaagactttg agcagctctg tgaagaaatt     3420

caggaatcta gaaagaaaag aggttgtagc tcctccaaat atgccccgtc ttactaccat     3480

gtgatgccaa agcaaaattc cactcttgtt ggtgataaaa gatcagaccc agagcagaat     3540

gaaaagctaa agacaccgag tactcctgtg gcttgcagca ctcctgctca gttgaagagg     3600

aaaattcgca aaaagtcaaa ctggtactta ggcaccataa aaaagcgaag gaagatttca     3660

caggcaaagg atgatagcca gaatgccata gatcacaaaa ttgagagtga tacagaggaa     3720

actcaagaca caagtgtaga tcataatgag accggaaaca caggagagtc ttcggtggaa     3780

gaaaatgaaa aacagcaaaa tgcctctgaa agcaaactgg aattgagaaa taattcaaat     3840

acttgtaata tagagaatga gcttgaagac tctaggaaga ctacagcatg tacagaattg     3900

agagacaaga ttgcttgtaa tggagatgct tctagctctc agataataca tatttctgat     3960

gaaaatgaag gaaaagaaat gtgtgttctg cgaatgactc gagctagacg ttcccaggta     4020

gaacagcagc agctcatcac tgttgaaaag gctttggcaa ttctttctca gcctacaccc     4080

tcacttgttg tggatcatga gcgattaaaa aatcttttga agactgttgt taaaaaaagt     4140

caaaactaca acatatttca gttggaaaat ttgtatgcag taatcagcca atgtatttat     4200

cggcatcgca aggaccatga taaaacatca cttattcaga aaatggagca agaggtagaa     4260

aacttcagtt gttccagatg atgatgtcat ggtatcgagt attctttata ttcagttcct     4320

atttaagtca tttttgtcat gtccgcctaa ttgatgtagt atgaaaccct gcatctttaa     4380

ggaaaagatt aaaatagtaa aataaaagta tttaaacttt cctgatattt atgtacatat     4440

taagataaat gtcatgtgta agataactga taaatattgg aactttgcta gaacaagacc     4500

ctgtagtaat agtaataata gttgaagttt ggccaactct taataaagtt attttggtaa     4560

ctaatgtttt atggcactta agaataatta gcagcgttaa attttgtttg tattaagcac     4620

ttttaatttt atccttccta aaaatagttt attgtatctg acaagaaact tacttaacca     4680

ttgtgtcctt cccatctttt ttgtcatctt tgttttcttc aaatgccctc ctcccatctg     4740

ccttgagatt ccctcgtctt cacttaaaag ccagagtgca agtcatgatt tgcgggaggg     4800

ctcttgaacc acttctggct gcaccacaat tctgtacttg agtatcacag tcattgtttt     4860

tgagacaaac atttttataa ttctaatttg ggttaataaa gattttaaat atttcttggt     4920

ttacttttgt aattatatac acaacaaatg tattaataac taccttgtta aacacctttt     4980

aatagcacaa ggtttttata tttgcaagct gttgatatct ttctaaaact gtttaggtta     5040

tagtctattg atacttttta tatacaattt tataaatata aatattataa ttttatatta     5100

atggtaccaa aaatacattt cttaaggtta aaagcatgca cttccatgca tacttgcttt     5160

tggggagagt ggggagaaga cattctaata atcagtttgt gaaatagctt ctgttggaaa     5220

ccttttgagg ggaataagga atggtcatct aaaatgagag attctggatt ttaatgcagt     5280

tcaaagttga gctgtatttt tgttgttgat ttatctggat tttttttaaa gccttctaaa     5340

acccagtgaa ttcaatacct taattagtac atactatctt atgtaatgca taaagcaatg     5400

ccagtcactg agaacattta aatatattta tattcctgga gatacacatt ctcatttttg     5460

ttggtttatt ataaattatt cttctagatg catcttttat aactaggatt tcattttgtg     5520

tgtatagctt atgtaataaa ttttaaaggt gaaaactctc ttaaaaaaaa aaaaaaaaaa     5580


<210>  2019
<211>  4363
<212>  DNA
<213>  homo sapiens

<400>  2019
gcgtgggctc ccgatgggct gcctgagcgg gtgcgcgggc aacttccggt gtgggtgacg       60

agtggtggcc gaagcagggg gacagcaagg gacgctcagg cggggaccat ggcggacggc      120

ggctcggagc gggctgacgg gcgcatcgtc aagatggagg tggactacag cgccacggtg      180

gatcagcgcc tacccgagtg tgcgaagcta gccaaggctt ccgatatggt atcgacatcc      240

cgtatcttag ttgcagtagt gaagatgtgc tatgaggcta aagaatggga tttacttaat      300

gaaaatatta tgcttttgtc caaaaggcgg agtcagttaa aacaagctgt tgccaaaatg      360

gttcaacagt gctgtactta tgttgaggaa atcacagacc ttcctatcaa acttcgatta      420

attgatactc tacgaatggt taccgaaggc aagatttatg ttgaaattga gcgtgcgcga      480

ctgactaaaa cattagcaac tataaaagaa caaaatggtg atgtgaaaga ggcagcctcc      540

attttacagg agttacaggt ggaaacctac gggtcaatgg aaaagaaaga gcgagtggaa      600

tttattttgg agcaaatgag gctctgccta gctgtgaagg attacattcg aacacaaatc      660

atcagcaaga aaattaacac caaatttttc caggaagaaa atacagagaa attaaagttg      720

aagtactata atttaatgat tcagctggat caacatgagg gatcctattt gtctatttgt      780

aagcactaca gagcaatata tgatactccc tgtatacagg cagaaagtga aaaatggcag      840

caggctctga agagtgttgt actctatgtt atcctggctc cttttgacaa tgaacagtca      900

gatttggttc accgaataag tggtgacaag aagttagaag aaattcccaa atacaaggat      960

cttttaaagc tttttaccac aatggagttg atgcgttggt ccacacttgt tgaggactat     1020

ggaatggaat taagaaaagg ttcccttgag agtcctgcaa cggatgtttt tggttctaca     1080

gaggaaggtg aaaaaaggtg gaaagacttg aagaacagag ttgttgaaca taatattaga     1140

ataatggcca agtattatac tcggataaca atgaaaagga tggcacagct tctggatcta     1200

tctgttgatg agtccgaagc ctttctctca aatctagtag ttaacaagac catctttgct     1260

aaagtagaca gattagcagg aattatcaac ttccagagac ccaaggatcc aaataattta     1320

ttaaatgact ggtctcagaa actgaactca ttaatgtctc tggttaacaa aactacgcat     1380

ctcatagcca aagaggagat gatacataat ctacaataag ggtcttagtg ctttagaaaa     1440

aagttaaaat tggaagtcat taaaaaaaga ctgttataat ggtgtatatg ttggggtttt     1500

ttttctaagc ttctttgtct taaattttaa aatagtgaat atgtttgaga ctccctttga     1560

cctttcagtt ccccaagttc attgttaact ttgcatttgc aattggtgca aaaatacaga     1620

tttctgtcgt ctgaatacac aaaaagttgt gtcataactt acccagatat gtttttctat     1680

catttgaaac ctttttagct actgtttgtt ttcattcaac taacaaacat attccaataa     1740

taaaagcagt atatacatat ttcctttcta cagttacctc tgattctcaa cattttgtgg     1800

ggtagtgatt tggcaagtgt tttttaaata aaacaaatct cattgtaaag ctatcagtca     1860

tttagtagaa tagaaaagca acatagagca tacaagaaca tttgggatag agttgtgatt     1920

tgtgaagaat ttgtactttg atattgtggc ggaaagtcta gactgagtgt gtatgctggt     1980

aaactgtaga cttttttttt tttttttttg agtccggctg gttccaatca cagtagcttg     2040

attgctttca gccctcatcc tctcacttga tcagttgttc aacagaatca gctgacataa     2100

ttgacacagt ttattgggtg ttaagtccgc tctataggga tagtgactac tttttttttt     2160

tttttttttt tgctcttctt cctctcccct ttctttatat gggtttaaat ttaacataaa     2220

gttgttttta taaggcttat ttgtggcttt aacttgtaag tctgattaca tcattattgt     2280

tccaaattca ttatctctgt aggaactttt agttccatta tatgaacact ggataaccta     2340

atttttttta atgctttaaa aaaatggcaa aaagacgtca ggccaccctc atagtaagtg     2400

gtgtagtatt aaaatatttt cacggaatta aaagtagctt gctgtcaaag aaacacctga     2460

gatgaattgg tgtgaacgaa ttttgcaagt ttaatttgat ttatttcaga gaaaatagaa     2520

aaaacaatgt tagaaggtta tttaaaatga tacttaaata aagaaagtgt gaggtctact     2580

ttaaaaaaat tcaaatgaag agaaaaagaa aaacagcatt ctagaaatgg catttctcct     2640

aattaatttt ccacttaatg gaagattatc aattgtccta ttttatgatc ccaggactga     2700

agacagttgt gggatatctg tcatatttat cctgtgagtc attgtgaata atgacataca     2760

gtactgaagt aatctgattt tattctttgg aaattcaatg cattggtcac actaataaca     2820

tcaacatctg ctatcactta tctttttaaa actaaccaaa aaaggccggg tgcagtggat     2880

cccagcactt tgggaggcca aggcgggtgg atcatctaag gtcaggattt cgagactagc     2940

ctggccaaca tggcaaaacc ctgtctctac taaaaaaaat acaaaaattt gccgggcgtg     3000

gtggcgtgtg cctgtagtcc cagttacttg ggaggctgag gtgggagaat tccttgaagc     3060

caggaggcgg aggttgcagt gagccaagat cacaccattg cactccagcc tgggtgacag     3120

agtgagactc cgtctcaaaa aaaaaaaaac aaaactggaa agttcagaaa cagaagttca     3180

cactaacaga gtatggtttt aattttcctt tgaatgaaaa ggatagaaga taaaattgtg     3240

tattgttaac atgtaaataa aattggagct aatttgaaac tagcttctca ataacttcat     3300

ctttctagag actcattacc tgtgggcttg tcaaacctgg actatttggc caaataggtt     3360

gctatagaga ttgcaagtgt tcctcctctt tatttttttc atattttttg agacggagtt     3420

tcactcttgt tgcccaggct ggattgcagt gtcacgatct cggctcactg caacctttgc     3480

ctcccatatt caagcagttc tcctgcctca acctcccaag tagctgggat tataggcgcc     3540

tgccaccaca cctagctaat ttttgtgttt ttagtagaga tggtttcatc atgttggccg     3600

ggctggtctc aaactcctga cctcaggtga tccacccgcc ttggctgccc aaagtgctgg     3660

gattacaggc atgagccact gcacccaact cctctttcgt ctttctttaa cacacactag     3720

gctctttgtg tattatgatt cagtgctatt tgtaactgtg tcccagtgac caaattgcac     3780

tcgactcgat cagctgttca tccatttcgt gttttttcct gtcaaacatt aatccagcaa     3840

atatatgagg tatttaccaa tttattttct tagtattaca aaataattca ttagcataaa     3900

gtacaatagt gaaatatttg agttgttcgg aacctcaatt aatcctgttt tacatttcag     3960

acctaaagct ggcaatcagg agaagaagca ctttgtttta aatgtggaga agataacact     4020

tgattccatt tcattgtcat tagtgtatta accagcagga gaggtgatga gccatttttc     4080

aaatgaaata ccttttattt ccatataatt tttttatttt agagttcaat agctgtttct     4140

atgattatcc tcaatttcca tatgttactg aatctgaaaa acatctttaa aattcaaaca     4200

gttccatttt ctctcttgta agtgttaaat gtgataaaag tacatatttt aaattgtttt     4260

cagctcttgg atatagcagc aataaaaaca ctaatttgtg ggtatttaag aaaacctgga     4320

gaataaactc atactttaaa agatcaaaaa aaaaaaaaaa aaa                       4363


<210>  2020
<211>  4363
<212>  DNA
<213>  homo sapiens

<400>  2020
gcgtgggctc ccgatgggct gcctgagcgg gtgcgcgggc aacttccggt gtgggtgacg       60

agtggtggcc gaagcagggg gacagcaagg gacgctcagg cggggaccat ggcggacggc      120

ggctcggagc gggctgacgg gcgcatcgtc aagatggagg tggactacag cgccacggtg      180

gatcagcgcc tacccgagtg tgcgaagcta gccaaggctt ccgatatggt atcgacatcc      240

cgtatcttag ttgcagtagt gaagatgtgc tatgaggcta aagaatggga tttacttaat      300

gaaaatatta tgcttttgtc caaaaggcgg agtcagttaa aacaagctgt tgccaaaatg      360

gttcaacagt gctgtactta tgttgaggaa atcacagacc ttcctatcaa acttcgatta      420

attgatactc tacgaatggt taccgaaggc aagatttatg ttgaaattga gcgtgcgcga      480

ctgactaaaa cattagcaac tataaaagaa caaaatggtg atgtgaaaga ggcagcctcc      540

attttacagg agttacaggt ggaaacctac gggtcaatgg aaaagaaaga gcgagtggaa      600

tttattttgg agcaaatgag gctctgccta gctgtgaagg attacattcg aacacaaatc      660

atcagcaaga aaattaacac caaatttttc caggaagaaa atacagagaa attaaagttg      720

aagtactata atttaatgat tcagctggat caacatgagg gatcctattt gtctatttgt      780

aagcactaca gagcaatata tgatactccc tgtatacagg cagaaagtga aaaatggcag      840

caggctctga agagtgttgt actctatgtt atcctggctc cttttgacaa tgaacagtca      900

gatttggttc accgaataag tggtgacaag aagttagaag aaattcccaa atacaaggat      960

cttttaaagc tttttaccac aatggagttg atgcgttggt ccacacttgt tgaggactat     1020

ggaatggaat taagaaaagg ttcccttgag agtcctgcaa cggatgtttt tggttctaca     1080

gaggaaggtg aaaaaaggtg gaaagacttg aagaacagag ttgttgaaca taatattaga     1140

ataatggcca agtattatac tcggataaca atgaaaagga tggcacagct tctggatcta     1200

tctgttgatg agtccgaagc ctttctctca aatctagtag ttaacaagac catctttgct     1260

aaagtagaca gattagcagg aattatcaac ttccagagac ccaaggatcc aaataattta     1320

ttaaatgact ggtctcagaa actgaactca ttaatgtctc tggttaacaa aactacgcat     1380

ctcatagcca aagaggagat gatacataat ctacaataag ggtcttagtg ctttagaaaa     1440

aagttaaaat tggaagtcat taaaaaaaga ctgttataat ggtgtatatg ttggggtttt     1500

ttttctaagc ttctttgtct taaattttaa aatagtgaat atgtttgaga ctccctttga     1560

cctttcagtt ccccaagttc attgttaact ttgcatttgc aattggtgca aaaatacaga     1620

tttctgtcgt ctgaatacac aaaaagttgt gtcataactt acccagatat gtttttctat     1680

catttgaaac ctttttagct actgtttgtt ttcattcaac taacaaacat attccaataa     1740

taaaagcagt atatacatat ttcctttcta cagttacctc tgattctcaa cattttgtgg     1800

ggtagtgatt tggcaagtgt tttttaaata aaacaaatct cattgtaaag ctatcagtca     1860

tttagtagaa tagaaaagca acatagagca tacaagaaca tttgggatag agttgtgatt     1920

tgtgaagaat ttgtactttg atattgtggc ggaaagtcta gactgagtgt gtatgctggt     1980

aaactgtaga cttttttttt tttttttttg agtccggctg gttccaatca cagtagcttg     2040

attgctttca gccctcatcc tctcacttga tcagttgttc aacagaatca gctgacataa     2100

ttgacacagt ttattgggtg ttaagtccgc tctataggga tagtgactac tttttttttt     2160

tttttttttt tgctcttctt cctctcccct ttctttatat gggtttaaat ttaacataaa     2220

gttgttttta taaggcttat ttgtggcttt aacttgtaag tctgattaca tcattattgt     2280

tccaaattca ttatctctgt aggaactttt agttccatta tatgaacact ggataaccta     2340

atttttttta atgctttaaa aaaatggcaa aaagacgtca ggccaccctc atagtaagtg     2400

gtgtagtatt aaaatatttt cacggaatta aaagtagctt gctgtcaaag aaacacctga     2460

gatgaattgg tgtgaacgaa ttttgcaagt ttaatttgat ttatttcaga gaaaatagaa     2520

aaaacaatgt tagaaggtta tttaaaatga tacttaaata aagaaagtgt gaggtctact     2580

ttaaaaaaat tcaaatgaag agaaaaagaa aaacagcatt ctagaaatgg catttctcct     2640

aattaatttt ccacttaatg gaagattatc aattgtccta ttttatgatc ccaggactga     2700

agacagttgt gggatatctg tcatatttat cctgtgagtc attgtgaata atgacataca     2760

gtactgaagt aatctgattt tattctttgg aaattcaatg cattggtcac actaataaca     2820

tcaacatctg ctatcactta tctttttaaa actaaccaaa aaaggccggg tgcagtggat     2880

cccagcactt tgggaggcca aggcgggtgg atcatctaag gtcaggattt cgagactagc     2940

ctggccaaca tggcaaaacc ctgtctctac taaaaaaaat acaaaaattt gccgggcgtg     3000

gtggcgtgtg cctgtagtcc cagttacttg ggaggctgag gtgggagaat tccttgaagc     3060

caggaggcgg aggttgcagt gagccaagat cacaccattg cactccagcc tgggtgacag     3120

agtgagactc cgtctcaaaa aaaaaaaaac aaaactggaa agttcagaaa cagaagttca     3180

cactaacaga gtatggtttt aattttcctt tgaatgaaaa ggatagaaga taaaattgtg     3240

tattgttaac atgtaaataa aattggagct aatttgaaac tagcttctca ataacttcat     3300

ctttctagag actcattacc tgtgggcttg tcaaacctgg actatttggc caaataggtt     3360

gctatagaga ttgcaagtgt tcctcctctt tatttttttc atattttttg agacggagtt     3420

tcactcttgt tgcccaggct ggattgcagt gtcacgatct cggctcactg caacctttgc     3480

ctcccatatt caagcagttc tcctgcctca acctcccaag tagctgggat tataggcgcc     3540

tgccaccaca cctagctaat ttttgtgttt ttagtagaga tggtttcatc atgttggccg     3600

ggctggtctc aaactcctga cctcaggtga tccacccgcc ttggctgccc aaagtgctgg     3660

gattacaggc atgagccact gcacccaact cctctttcgt ctttctttaa cacacactag     3720

gctctttgtg tattatgatt cagtgctatt tgtaactgtg tcccagtgac caaattgcac     3780

tcgactcgat cagctgttca tccatttcgt gttttttcct gtcaaacatt aatccagcaa     3840

atatatgagg tatttaccaa tttattttct tagtattaca aaataattca ttagcataaa     3900

gtacaatagt gaaatatttg agttgttcgg aacctcaatt aatcctgttt tacatttcag     3960

acctaaagct ggcaatcagg agaagaagca ctttgtttta aatgtggaga agataacact     4020

tgattccatt tcattgtcat tagtgtatta accagcagga gaggtgatga gccatttttc     4080

aaatgaaata ccttttattt ccatataatt tttttatttt agagttcaat agctgtttct     4140

atgattatcc tcaatttcca tatgttactg aatctgaaaa acatctttaa aattcaaaca     4200

gttccatttt ctctcttgta agtgttaaat gtgataaaag tacatatttt aaattgtttt     4260

cagctcttgg atatagcagc aataaaaaca ctaatttgtg ggtatttaag aaaacctgga     4320

gaataaactc atactttaaa agatcaaaaa aaaaaaaaaa aaa                       4363


<210>  2021
<211>  2031
<212>  DNA
<213>  homo sapiens

<400>  2021
gttccggcgc cggctttggc ggaggggtgg gacttgcacc ggcgtctctt cttctaactg       60

cagtttgtgg cagcgccatt ttgaatgtgc agctgcagcg ggcgcctgta tccggtgtcc      120

gaggcgaact cagtaagatg atgttaagag gaaacctgaa gcaagtgcgc attgagaaaa      180

acccggcccg ccttcgcgcc ctggagtccg cggtgggcga gagcgagccg gcggccgcgg      240

cagccatggc gctcgctctt gccggggagc cggcaccgcc cgcgcccgcg cctccagagg      300

accacccgga cgaggagatg gggttcacta tcgacatcaa gagtttcctc aagccgggcg      360

agaagacgta cacgcagcgc tgccgcctct tcgtgggaaa tctgcccacc gacatcacgg      420

aggaggactt caagaggctc ttcgaacgct atggcgagcc cagcgaagtc ttcatcaacc      480

gggaccgtgg cttcggcttc atccgcttgg aatccagaac cctggctgaa attgcaaaag      540

cagagctgga cggcaccatt ctcaagagca gacctctacg gattcgcttc gctacacatg      600

gagcagcctt gactgtcaag aacctttctc cagttgtttc caatgagctg ctagagcaag      660

cattttctca gtttggtcca gtagagaaag ctgttgtggt tgtggatgat cgcggtagag      720

ctacaggaaa aggttttgta gagtttgcag caaaacctcc tgcacgaaag gctctggaaa      780

gatgtggtga tggggcattc ttgctaacaa cgacccctcg tccagtcatt gtggaaccca      840

tggagcagtt tgatgatgaa gatggcttgc cagagaagct gatgcagaaa actcaacaat      900

atcataagga aagagaacaa ccaccacgtt ttgctcaacc tgggacattt gaatttgagt      960

atgcatctcg atggaaggct cttgatgaaa tggaaaagca gcagcgtgag caggttgata     1020

gaaacatcag agaagccaaa gagaaactgg aggcagaaat ggaagcagct aggcatgaac     1080

accaattaat gctaatgagg caagatctaa tgaggcgtca agaagaactc agacgcttgg     1140

aagaactcag aaaccaagag ttgcaaaaac ggaagcaaat acaactaaga catgaagagg     1200

agcatcggcg gcgtgaggaa gaaatgatcc gacacagaga acaggaggaa ctgaggcgac     1260

agcaagaggg ctttaagcca aactacatgg aaaatagaga acaggaaatg agaatgggtg     1320

atatgggtcc ccgtggagca ataaacatgg gagatgcgtt tagcccagcc cctgctggta     1380

accaaggtcc tcctccaatg atgggtatga atatgaacaa cagagcaact atacctggcc     1440

caccaatggg tcctggtcct gccatgggac cagaaggagc cgcaaatatg ggaactccaa     1500

tgatgccaga taatggagca gtgcacaatg acagatttcc tcaaggacca ccatctcaga     1560

tgggttcacc tatggggagt agaacaggtt ctgaaacccc tcaagcacca atgagtggtg     1620

taggtcctgt gagtggtggt cctggtggct ttggtagagg aagtcaaggg ggcaactttg     1680

aaggccctaa taagcgtcgt agatattaaa cattcgttca ttcctggcta tctagaaaaa     1740

aaaaagtcag tggtatgcct ttatactttt acctgttatc tggaagaaat ggttttattg     1800

ttaatgtatg tagacttaaa agtttttttt tttttgtaaa acttgaggtt tttgtatttt     1860

tctttattca tgagctttgt agattagaat ggtaatgatg ctcatcattt tgaatgttga     1920

aatgtgtttg tgactttagc taaatataag tattccatag tactgtgaaa tctatgtagt     1980

taatctcaat aaagaaatca ttttggataa tttaaaaaaa aaaaaaaaaa a              2031


<210>  2022
<211>  1769
<212>  DNA
<213>  homo sapiens

<400>  2022
gttccggcgc cggctttggc ggaggggtgg gacttgcacc ggcgtctctt cttctaactg       60

cagtttgtgg cagcgccatt ttgaatgtgc agctgcagcg ggcgtgagtt gggggaggac      120

gggttgccga ctcgcctacc tagcggtctc ttgattgtcg atattttgtt ggcataggtt      180

tatgtagaga cgtatacata tatatagaca cactgtctat aaatctaggc ctgtatccgg      240

tgtccgaggc gaactcagta agatgatgtt aagaggaaac ctgaagcaag tgcgcattga      300

gaaaaacccg gcccgccttc gcgccctgga gtccgcggtg ggcgagagcg agccggcggc      360

cgcggcagcc atggcgctcg ctcttgccgg ggagccggca ccgcccgcgc ccgcgcctcc      420

agaggaccac ccggacgagg agatggggtt cactatcgac atcaagagtt tcctcaagcc      480

gggcgagaag acgtacacgc agcgctgccg cctcttcgtg ggaaatctgc ccaccgacat      540

cacggaggag gacttcaaga ggctcttcga acgctatggc gagcccagcg aagtcttcat      600

caaccgggac cgtggcttcg gcttcatccg cttggaatcc agaaccctgg ctgaaattgc      660

aaaagcagag ctggacggca ccattctcaa gagcagacct ctacggattc gcttcgctac      720

acatggagca gccttgactg tcaagaacct ttctccagtt gtttccaatg agctgctaga      780

gcaagcattt tctcagtttg gtccagtaga gaaagctgtt gtggttgtgg atgatcgcgg      840

tagagctaca ggaaaaggtt ttgtagagtt tgcagcaaaa cctcctgcac gaaaggctct      900

ggaaagatgt ggtgatgggg cattcttgct aacaacgacc cctcgtccag tcattgtgga      960

acccatggag cagtttgatg atgaagatgg cttgccagag aagctgatgc agaaaactca     1020

acaatatcat aaggaaagag aacaaccacc acgttttgct caacctggga catttgaatt     1080

tgagtatgca tctcgatgga aggctcttga tgaaatggaa aagcagcagc gtgagcaggt     1140

tgatagaaac atcagagaag ccaaagagaa actggaggca gaaatggaag cagctaggca     1200

tgaacaccaa ttaatgctaa tgaggcaaga tctaatgagg cgtcaagaag aactcagacg     1260

cttggaagaa ctcagaaacc aagagttgca aaaacggaag caaatacaac taagacatga     1320

agaggagcat cggcggcgtg aggaagaaat gatccgacac agagaacagg aggaactgag     1380

gcgacagcaa gagggcttta agccaaacta catggaaaat ggtgataaaa gaaaatgtgg     1440

ctgaagttac ccgaagttca gcttgcagtg taattcagaa gagttaagac cagaagtact     1500

ggaatcatac ttcctttcag tcttgccact tgcctagtga ggcttttccg aacctggaag     1560

gagacgtcta gaaatcccaa ctttgctgtg taaggaccat tagctgcaag tcagtggaag     1620

tctatagaaa gcagtgtgaa ttccatagtg gtcttgactt cttagcaagg atttgggata     1680

agtctaaaac ttcagactta aagctttgaa gcatgttaac tgcatgaaat attaaacatt     1740

tcgaacttct ttaaaaaaaa aaaaaaaaa                                       1769


<210>  2023
<211>  1769
<212>  DNA
<213>  homo sapiens

<400>  2023
gttccggcgc cggctttggc ggaggggtgg gacttgcacc ggcgtctctt cttctaactg       60

cagtttgtgg cagcgccatt ttgaatgtgc agctgcagcg ggcgtgagtt gggggaggac      120

gggttgccga ctcgcctacc tagcggtctc ttgattgtcg atattttgtt ggcataggtt      180

tatgtagaga cgtatacata tatatagaca cactgtctat aaatctaggc ctgtatccgg      240

tgtccgaggc gaactcagta agatgatgtt aagaggaaac ctgaagcaag tgcgcattga      300

gaaaaacccg gcccgccttc gcgccctgga gtccgcggtg ggcgagagcg agccggcggc      360

cgcggcagcc atggcgctcg ctcttgccgg ggagccggca ccgcccgcgc ccgcgcctcc      420

agaggaccac ccggacgagg agatggggtt cactatcgac atcaagagtt tcctcaagcc      480

gggcgagaag acgtacacgc agcgctgccg cctcttcgtg ggaaatctgc ccaccgacat      540

cacggaggag gacttcaaga ggctcttcga acgctatggc gagcccagcg aagtcttcat      600

caaccgggac cgtggcttcg gcttcatccg cttggaatcc agaaccctgg ctgaaattgc      660

aaaagcagag ctggacggca ccattctcaa gagcagacct ctacggattc gcttcgctac      720

acatggagca gccttgactg tcaagaacct ttctccagtt gtttccaatg agctgctaga      780

gcaagcattt tctcagtttg gtccagtaga gaaagctgtt gtggttgtgg atgatcgcgg      840

tagagctaca ggaaaaggtt ttgtagagtt tgcagcaaaa cctcctgcac gaaaggctct      900

ggaaagatgt ggtgatgggg cattcttgct aacaacgacc cctcgtccag tcattgtgga      960

acccatggag cagtttgatg atgaagatgg cttgccagag aagctgatgc agaaaactca     1020

acaatatcat aaggaaagag aacaaccacc acgttttgct caacctggga catttgaatt     1080

tgagtatgca tctcgatgga aggctcttga tgaaatggaa aagcagcagc gtgagcaggt     1140

tgatagaaac atcagagaag ccaaagagaa actggaggca gaaatggaag cagctaggca     1200

tgaacaccaa ttaatgctaa tgaggcaaga tctaatgagg cgtcaagaag aactcagacg     1260

cttggaagaa ctcagaaacc aagagttgca aaaacggaag caaatacaac taagacatga     1320

agaggagcat cggcggcgtg aggaagaaat gatccgacac agagaacagg aggaactgag     1380

gcgacagcaa gagggcttta agccaaacta catggaaaat ggtgataaaa gaaaatgtgg     1440

ctgaagttac ccgaagttca gcttgcagtg taattcagaa gagttaagac cagaagtact     1500

ggaatcatac ttcctttcag tcttgccact tgcctagtga ggcttttccg aacctggaag     1560

gagacgtcta gaaatcccaa ctttgctgtg taaggaccat tagctgcaag tcagtggaag     1620

tctatagaaa gcagtgtgaa ttccatagtg gtcttgactt cttagcaagg atttgggata     1680

agtctaaaac ttcagactta aagctttgaa gcatgttaac tgcatgaaat attaaacatt     1740

tcgaacttct ttaaaaaaaa aaaaaaaaa                                       1769


<210>  2024
<211>  3282
<212>  DNA
<213>  homo sapiens

<400>  2024
cgctccccgc tgcctattct catccggggt cacgtcggtc ttccgggtgt ctttgacagg       60

gttttctacg ccgctttttc ggcgactttt tgctcttccg ctttttgcca ccgcccccaa      120

ccttctatat ccttgcagcc cctacctttt cttgtgttgc tcctcccctg gcagccgtga      180

ggggggttag atctcagccg gagccggagc tgggcctagc tgtcccacgg gccaccacta      240

cctcctttgg ttcgggagaa agctacgacc aagtacgccc agctcgggcc ttagaacttc      300

tgaacgggca gtgcgggtag gccctgctta gcccttcccg gaggacacct gaccaaaaga      360

ggaagatagt cttgggaccc ttgcatggtg tttcaaaggg tggtgaagaa ctaaggtaga      420

agaatacatg ttcacttcca gtgaacaaga gcatgttccc aaactcaatt ttgggtcgcc      480

cacccttcac tccaaatcat caacaacata ataacttctt taccctgtca cctactgttt      540

attcacacca gcagcttata gatgcacaat tcaactttca gaatgcagac ttgtctagag      600

ctgtgtcatt acagcagctg acatatggaa atgtcagtcc aatacagacc tcagcttccc      660

cattatttcg aggaaggaag agattaagcg atgaaaaaaa ccttcctctt gacggtaaac      720

ggcaacgttt ccattcaccc caccaagagc caactgtagt taaccagata gtgcctttat      780

caggtgaacg aagatactca atgccaccat tgtttcatac acattatgta ccagatatag      840

tcagatgtgt tccacctttt cgagaaattg catttttaga acctagagaa atcacactgc      900

ctgaggccaa agataagttg agtcagcaga tactggagtt atttgaaaca tgtcagcagc      960

aaataagtga tttaaagaag aaagaactct gtcgaacaca gctgcagaga gaaattcagc     1020

tgttatttcc acaaagcaga ctttttttgg ttgggtcctc tttaaatgga tttggtaccc     1080

ggagcagtga tggtgattta tgcctagttg ttaaggaaga accatgtttt tttcaggtaa     1140

atcagaagac tgaagcacgg catatactca ccttagtcca taaacacttc tgtactagac     1200

tttcgggcta cattgagaga cctcagctga ttcgagcaaa agtgccaatt gtgaagttca     1260

gggataaagt cagttgtgtg gagtttgact tgaatgtaaa caatattgtt ggaataagaa     1320

acacattcct tctcagaact tatgcatacc ttgaaaatcg agttcgtccg ttagtgctgg     1380

tgattaagaa gtgggcaagt caccatcaga taaatgatgc cagtcgtggt actttaagca     1440

gctatagtct tgtattgatg gttttgcact atttacaaac cctacctgaa cccatccttc     1500

catccctcca aaaaatttac ccagagtctt ttagtcctgc tatacagctg caccttgtac     1560

atcaagctcc atgtaatgtt cctccttacc tctcaaagaa tgaatcaaac cttggggacc     1620

tcttactggg ctttcttaaa tattatgcta cagaatttga ctggaatagt caaatgattt     1680

cagttcgtga agccaaagcc attccaaggc ctgatggtat tgaatggaga aataaataca     1740

tctgtgtaga agaacctttt gatggaacaa atacagccag agcagtgcac gaaaagcaga     1800

aatttgatat gatcaaggat caatttttaa agtcatggca cagattgaaa aacaagagag     1860

atttgaacag tatactacct gtaagagctg ctgtcctgaa aagataactg gcctctattt     1920

cttaataaat tcttccaaga aataaagaac aatagtttca tcataataca ttatgtttac     1980

ctccatcata gttgcttttt tcatagttct tgttttcatg ttttattttt aaaaagacat     2040

ataaagattg catattttat tatgacattt cctaataaac ccctttgatt taaaaatgta     2100

tttttaaaaa tgtttacatt gatgatgagt aatattgcat gtgttttcag gtgatcagat     2160

aaaatatatt ttgggaaatt aactgaacaa ataaaaagtt tttgatataa cttcaattaa     2220

ttgtaccaca tgctaatcct gaagagatgt gtagaatttt ggaaagggtc taattcatac     2280

atgcttaaag tataacctac gttagatagt ttgttgtcaa agtctgttct agtaaagtga     2340

agattcaagt cagttgttca gttacttgaa gcaaaacgaa atctttcatt tcagtcaaat     2400

cactgcagtc atgaaatact gaacaattgc cttaagtctt tgcttgactc actgggatag     2460

actgaggctt tgggtgtgtc tgtattagca tttcattagt acttcacatg cttttgatgt     2520

actcttgaga ttgctttaaa ttttgtattg aaacaacaat acattttgca ctgtagtaat     2580

gggagcacta actcttacaa cagttagtga atcgttttaa agaatcagtt cagtgtagac     2640

attttgaaaa gattgtttcc tgtgctttac gatagcttag tgcaatgtgc acttctgttt     2700

tacttgccat tttcctgctc tgttttctct gtgacatgaa gcaacagaaa ctgagatcaa     2760

agttaagatt atatcctgtt tgtagtatca gatatttttc tgtgtacaat tataggattg     2820

taatctaaac tggaattttt aggcagtaag tcaccacaaa atgttttaga taagacacaa     2880

taaaattatt ataaataaaa gcttaatgtt tgtaaaaaat ctctttttta gtatttcttt     2940

tttcacatga aagaagtggt ggctgctaaa aaaaaagcta cagtgtttat taagggtctt     3000

tttgatttat gtaaatattt gtaaattggt cagtgcctgt aaatttaaat ataaaaagta     3060

accttgaaaa cagttttaac tttttcaaaa gaactatgtc caacattttt tagacctgct     3120

gtagtacagt tttgtacctc taacgtattt tttttttgca gaccaaatgc taaaactttt     3180

gcttttcttt gacttgtaaa aggtgcacat tttcattttc ttccttaagt tcaaattttt     3240

gtatgatgtc aaatgcaata aaatttatat atggacattg tt                        3282


<210>  2025
<211>  967
<212>  DNA
<213>  homo sapiens

<400>  2025
ctctgctctc ctcccagtct cccccgcgct gcgtgcagta aggtagccgc cgccgccgcc       60

gccgccgcgt cccctcgccg gctcgctggt accggcagtg ccatggcggc cttcagcaag      120

tacttgacgg cgcgaaactc ctcgctggct ggtgccgcgt tcctgctgct ctgcctgctc      180

cacaagcggc gccgcgccct cggcctgcac ggtaagaaaa gtggaaaacc accattacag      240

aacaatgaga aagaggggaa aaaggagcga gctgtggtgg acaaggtgtt tttctcaagg      300

ctcatacaga ttctgaaaat catggtccct agaacatttt gtaaagagac aggttacttg      360

gtacttattg ctgttatgct ggtgtctcga acatattgtg atgtttggat gattcaaaat      420

gggacactaa ttgaaagtgg tatcattggt cgtagcagga aagatttcaa gagatactta      480

ctcaacttca tcgctgccat gcctcttatc tctctggtta ataacttctt gaagtatggg      540

ttaaatgagc ttaaactgtg cttccgagta aggctcacta aatacctcta tgaggagtat      600

cttcaagctt tcacatatta taaaatgggg aatctggaca acagaatagc taatccagac      660

cagctgctta cacaagatgt agaaaaattt tgtaacagtg tagtcgatct gtattcaaat      720

cttagtaagc catttttaga catagttttg tatatcttta agttaacgag tgcaattgga      780

gctcaggtac ttggaaaaat tttgtggcat taaaaaccag acaaatgtat tggccaggcg      840

tggtggctca tgcctgtaat cccagcactt tgggaggctg agatgggagg atcgcttgaa      900

tccaggagtt cgagacaagc ctggacaaaa agcgagaccc gcttctttaa aaaataataa      960

taaaaca                                                                967


<210>  2026
<211>  5768
<212>  DNA
<213>  homo sapiens

<400>  2026
aggcgccctc ccctcgccgg gggccgcgag ttgcatttgg taaaacccag ccccggaata       60

tatagatcgt tggagcgcaa tgaagtagcc tttggagaga agggagaggg cccgtcggac      120

agccacagcg gccagcgcag cggcagcggc ggcggcacca ccatcaccgc tcgcacccca      180

gccgcccggc ccgcgaccag gcagcggcgg ccgccggcgg gatcggagga ggcggcggag      240

cggcgaggag gaggagcagg agcgcgcagc cagcgggtcc acgcatctca gcacttccag      300

accaactccg gcaccttcca cacccctgcc cgggctgggg gctccgagag cggccgcgaa      360

gcgactccga tcctccctct gagccttgct cagctctgcc ccgcgcctcc cgggctccgg      420

tccgcgcggc ggggtccctg ctcctgcgcc ccgggcgcgc ttcccggaca ccccggtccc      480

cgcagccagg acaaagccat gaagccagcg ctgctggaag tgatgaggat gaacagaatc      540

tgccggatgg tgctggccac ttgcttggga tcctttatcc tggtcatctt ctatttccaa      600

agtatgttgc acccagtcat gcggaggaat ccctttggtg tggacatctg ctgccggaag      660

gggtcccgaa gccccctgca ggaactctac aacccaatcc agctggagct ctcaaacact      720

gctgtcctgc accagatgcg gcgggaccag gtgacagaca cgtgccgagc caacagcgcc      780

acaagccgta agcggagggt gctgaccccc aacgacctga agcacttggt ggtggatgag      840

gaccacgagc tcatctactg ctacgtgccc aaggtggcct gcaccaactg gaagcggctc      900

atgatggtcc tgaccgggcg ggggaagtac agcgacccca tggagatccc ggccaacgag      960

gcacacgtct ccgccaacct gaagaccctg aaccagtaca gcatcccaga aatcaaccac     1020

cgcttgaaaa gctacatgaa gttcctgttt gtccgggagc ccttcgagag gctagtgtcc     1080

gcctaccgca acaagttcac ccagaagtac aacatctcct tccacaagcg gtacggcacc     1140

aagatcatca aacgccagcg gaagaacgcc acccaggagg ccctgcgcaa aggggacgat     1200

gtcaaattcg aggagtttgt ggcctatctc atcgacccac acacccagcg ggaggagcct     1260

ttcaacgaac actggcaaac cgtctactca ctctgccatc cctgccacat ccactatgac     1320

ctcgtgggca agtacgagac actggaagag gattctaatt acgtcctgca gctggcagga     1380

gtgggcagct acctgaagtt ccccacctat gcaaagtcta cgagaactac tgatgaaatg     1440

accacagaat tcttccagaa catcagctca gagcaccaaa cgcagctgta cgaagtctac     1500

aaactcgatt ttttaatgtt caattactca gtgccaagct acctgaaatt ggaataaagg     1560

gggtggggag agggagagaa tcatgctttt taatttaaga tttttatttg tcaaaagaat     1620

tatatggata ttgggttatt ttgtaaatta atatttcttt ggggatgatg ctgcgagcag     1680

catagtgaga attatttaaa atccttcgta gggaaggaca gctgtctttg caggggaaat     1740

aggatgggtc gtccttgtct gtagaagtga atactgcaac actgtctcaa aggtttcttg     1800

tgttctggtg aattccatga attgtgcatt ccataaattc taattaatat tatttatagt     1860

tatttaaaca tggtctcatt atttcttttt gtggcagcaa aattctaaca tctttccaga     1920

agaaatctat gattcctgct ttgcttgcta cagctcattt gggggcatga atgttctcct     1980

tactaacctc tcatggagtc atgtgataac agccattgtc atgtgtatgg atgccaccat     2040

tcttgaattt ctgctagaaa taagtaggtt gctattgcac ttagagtcat ctttgcaagg     2100

gactcattcc aaaccaattc caatcgacct gaaagtccct tgcactaaag aaatgtgatt     2160

tttttttaac ccaaggagaa agttggttgt aacaattttt caccagaatt agcaatctga     2220

tagaataggc ttttttaaca ggaattttaa actggcggtg ccagttgcag tgaaggtgaa     2280

gtggctattg ctttatattc gacaaatatt tattgagcat ctactatata ctaggccctg     2340

aagatagagc gttgaacaaa cccaatagtc ttggccctca aaaagcttta tgtgacatag     2400

agcatccagc tcgacaatta gcaaacccct gatattattc atggacttga catgaggttt     2460

ggactattca tgagcaacag cagaaggtcc atgaccccta caaatttaca tttttctatg     2520

gcccatattt gaaaacctca cattcggagc aggccacttt atattcgtga gtgatcccaa     2580

gctcactgac caacagaaaa gatgctaaaa aaatgtgtcc tatcatgtgc ctgctccaac     2640

tgatgggtaa tgtctgcctt taagccccag aatggattct ccaggcacag tgtggaagag     2700

tgctgtggtt gattagcaat gtctgccttg ggtgaggaaa ggggaacact cctcaagtgc     2760

ctcctactgt catctccatt cagcctagca ccacatcccc atgtagaagt gttgtcttct     2820

actgcttgcc acgtacaagt gtgaaatgcc aaggtgagac tcgtacactt ggggatttgc     2880

aatggttttt acccctcatg aaggtcagag gtggactatt tgtacacata cacacatgca     2940

caccctctca cgtcctccag aggctgaaag actatcagca tcttggtaac tgccatgcat     3000

gagcagcaag gacagccttc cataatccat gccccatttc ctctggaagc ctggaaactt     3060

ttcatttcct gttccttgct aattaacatc taaacatgct tctcatttcc agccattgct     3120

gatgcttctc agttgaagtt tgagccacat ccctcttaca gctagtgaat gagttggtag     3180

cagctactgt atataataat aataatagtt ttaataatag gggagggtgg gatggggtgt     3240

gggtaagttt tgccttttgt tttgtttttg atgccgtata tagtgaaggg gtgaggatat     3300

tctaaacaaa caaaaattga ataatttatt cacagaaact attaagattg tattgtaaag     3360

ctcacagcaa gctcagtggg cagcagctgc aacatctcac cggggaaatt attttattta     3420

acgtgagtga gatgtgggcc ggagaaggta gctgaagcta tttataaaac gttgtgtacc     3480

ttcttccgag ctctctcccc tttgtgaagg gcgcagcaac tatacccttg atggatggag     3540

atttacgcaa tgtgttttac tgggtagagt gacagacctt ggctgtccct ggaattgaga     3600

atctggacct tatttccagg cagagaacac tgtcctcaga aatgggactt ctgataatga     3660

aacaggttgt ccaacatttt ctaatacgca ttctacagaa cacaggttcc aggaggcatc     3720

aggttggtgt gatgcagact aagggttttg tggtcaaata tccttaagaa acaaagttaa     3780

gtcagtttcc tttctgcaag gacttttcag ccttcaatgt gtgctgtgca tggtgaatcc     3840

ccaaaaataa tccttgagtc tgtagcattt cctgaactta catgaccagg atactctatt     3900

ttgcagatca ccccacagag ctagggttcc accgagtata ctttgcttag gttgacttag     3960

catatctgag gtcttcaagg ataaaaactg ccaccccaac acccttccat taaaaaaaaa     4020

atacaaaata gcaccacagt ctccatctgg tttatagcaa cagaggtact ttatttaatg     4080

aagcaatggt tctaatcctg gatactgcca cggactacaa ttctatccct cccagaggga     4140

gtggaggaag tcttgggtgg tgtggacaga aggaagagag gagagggtga gtggggtata     4200

gggcccaggg tggctcccta ctcctcaggc tcaaaaggat gctcagtggg aacagatgat     4260

ctcttgatga gtgcttcttc agtttcatag tttggaatcg ttcactgtgt gctttttggg     4320

gggttttcaa tggaaattca cgttgctttg catttctgtg tccgtctttg gtcagttgtg     4380

caagcctgct cactgtcatg tgaagatggc ctttcatctg gcttctctct cttaagtgag     4440

aaagattgtc cttcagggga catgacatca ataggtttct ggaatgaggg actctttctc     4500

cccgtgtttt gctttgtgtt cacattttct tttctaatgg cattgaaact ttaaaaaaaa     4560

tggattcaac tgtttttgca gaatgtagaa agtattctgt gtccttggtt aaagaaatcc     4620

acttgtgaag tgtgcctgga aaatgaaagt ttgtgttttt taaagaggaa tatttgaaac     4680

tgctttctat gcatgcttag ctggagaaaa gtacaggcag gcgtcccatc tcccagccac     4740

ttctcaaagg tgctgctgtg ttttaaagac caggtacagc cagggcagta tttgcaagga     4800

cattcctgct tactttatcc ctttggttgg aaagctctag atgattcccg cagctcctcc     4860

agaccccgcc tccctgccct ccccagctgg tctgggaaga ggtggtctgc tgacctgtgg     4920

tatctcagag gggacgttcc tcctcctccc tgtgcaccag gtgggctgca ccctcctgcc     4980

tattcaggat gtggatgcca caggagagca gcaggcagtg gaaacttcag ttgcactggt     5040

tctcctggtg gcaaaggcat gaagcacagg ggtcgattaa tccaggctac tagaaagctc     5100

cagagcaaag tgtgcgggtc ccacaaatgc ttggctggtg gggtctggat cagtgctgag     5160

atagagttgg cagaagaagc agaggcactc tgcttgcttt cctagccagt cctcccctac     5220

acacacacac acacacacac acacacacac acacaatctc agctgcgcca ttctgtgcaa     5280

tcccagtgac caaatccctt ccttgcccac ctctatgtca gcaggactga ccacatcact     5340

cccccgagtt cccaccacca gcatttcctc caaccttttt ccatcacaac cagttagaac     5400

cctacaggca acaaggcctt ctagaatccg cttaaccctt ggctgataac aggcaaattt     5460

cagtctgcta cactttgtta ggtccagaag gagctgccca tactactttc ttatgagcat     5520

gctcagtatg gcatatggac atgtaatgtc acatctttgt ggagtgtgat tttctttttt     5580

cacatatttg tatgcagtag agagcctgtt gtagaaaacg ctccctgtat cttgctgtac     5640

tgttaaagaa agctgaattc cacattgcca acaaaagcgt gaaaatgttc atgaaccttc     5700

ctccaggaaa agccattcaa gcctgattat ttttctaagt aacttcaatt aaattgaaga     5760

aaaaagaa                                                              5768


<210>  2027
<211>  1148
<212>  DNA
<213>  homo sapiens

<400>  2027
gcgccgagac ccgctcctgc agtattagtt cttgcagctg gtggtggcgg ctgaggcggc       60

atggatctca gcgagctgga gagagacaat acaggccgct gtcgcctgag ttcgcctgtg      120

cccgcggtgt gccgcaagga gccttgcgtc ctgggcgtcg atgaggcggg caggggcccc      180

gtgctgggcc ccatggtcta cgccatctgt tattgtcccc tgcctcgcct ggcagatctg      240

gaggcgctga aagtggcaga ctcaaagacc ctattggaga gcgagcggga aaggctgttt      300

gcgaaaatgg aggacacgga ctttgtcggc tgggcgctgg atgtgctgtc tccaaacctc      360

atctctacca gcatgcttgg gcgggtcaaa tacaacctga actccctgtc acatgataca      420

gccactgggc ttatacagta tgcattggac cagggcgtga acgtcaccca ggtattcgtg      480

gacaccgtag ggatgccaga gacataccag gcgcggctgc agcaaagttt tcccgggatt      540

gaggtgacgg tcaaggccaa agcagatgcc ctctacccgg tggttagtgc tgccagcatc      600

tgtgccaagg tggcccggga ccaggccgtg aagaaatggc agttcgtgga gaaactgcag      660

gacttggata ctgattatgg ctcaggctac cccaatgatc ccaagacaaa agcgtggttg      720

aaggagcacg tggagcctgt gttcggcttc ccccagtttg tccggttcag ctggcgcacg      780

gcccagacca tcctggagaa agaggcggaa gatgttatat gggaggactc agcatccgag      840

aatcaggagg gactcaggaa gatcacatcc tacttcctca atgaagggtc ccaagcccgt      900

ccccgttctt cccaccgata tttcctggaa cgcggcctgg agtcagcaac cagcctctag      960

cagctgcctc tacgcgctct acctgcttcc ccaacccaga cattaaaatt gtttaaggag     1020

aaccacacgt aggggatgta cttttgggac agaagcaagg tgggagtgtg ctctgcagcc     1080

gggtccagct acttcctttt ggaaccttaa atagaatggg tgttggttga ttaattttat     1140

ttaaaaaa                                                              1148


<210>  2028
<211>  6031
<212>  DNA
<213>  homo sapiens

<400>  2028
cttttcccat cgtgtagtca agagtctgtg ccagacttga aggctttact ttgttagcca       60

tgtgtttatg aacccccagc gctttcccta gatcttttgg ctgataatct caaacatgga      120

ggatgcttct gaatcttcac gaggggttgc tccattaatt aataatgtag ttctcccagg      180

ctctccgctg tctcttcctg tatcagtgac aggctgtaaa agtcatcgag tagccaataa      240

aaaggtagaa gcgaggagtg aaaagctcct cccaacagct cttcctcctt cagagccgaa      300

agtagatcag aaacttccca ggagctccga gaggcgggga agtggcggtg ggacgcaatt      360

ccccgcgcgg agtcgggcag tggcagcggg agaagcggca gccaggggcg cggcggggcc      420

ggagagaggc ggtcccctgg gaggacgggg tctcccctcg ttgcctttgt agtggagaag      480

gtggacaagt ggcagtcggc gtgatcgcag ggaagcgggg ccggcgcggg cggccgaggg      540

tccaggcgag cccgcgggcg gacgggagat gccgctgcta caccgaaagc cgtttgtgag      600

acagaagccg cccgcggacc tgcggcccga cgaggaagtt ttctactgta aagtcaccaa      660

cgagatcttc cgccactacg atgacttttt tgaacgaacc attctgtgca acagccttgt      720

gtggagttgt gctgtgacgg gtagacctgg actgacgtat caggaagcac ttgagtcaga      780

aaaaaaagca agacagaatc ttcagagttt tccagaacca ctaattattc cagttttata      840

cttgaccagc cttacccatc gttcgcgctt acatgaaatt tgtgatgata tctttgcata      900

tgtcaaggat cgatattttg tcgaagaaac tgtggaagtc attaggaaca atggtgcaag      960

gttgcagtgt aggattttgg aagtcctccc tccatcacat caaaatggtt ttgctaatgg     1020

acatgttaac agtgtggatg gagaaactat tatcatcagt gatagtgatg attcagaaac     1080

acaaagctgt tcttttcaaa atgggaagaa aaaagatgca attgatccct tactattcaa     1140

gtataaagtg caacccacta aaaaagaatt acatgagtct gctattgtta aagcaacaca     1200

aatcagccgg agaaaacacc tattttctcg tgataaacta aagctttttc tgaagcaaca     1260

ctgtgaacca caagatggag tcattaaaat aaaggcatca tctctttcaa cgtataaaat     1320

agcagaacaa gatttttctt atttcttccc tgatgatcca cccacattta tcttcagtcc     1380

tgctaacaga cgaagaggga gacctcccaa acgaatacat attagtcaag aggacaatgt     1440

tgctaataaa cagactcttg caagttatag gagcaaagct actaaagaaa gagataaact     1500

tttgaaacaa gaagaaatga agtcactggc ttttgaaaag gctaaattaa aaagagaaaa     1560

agcagatgcc ctagaagcga agaaaaaaga aaaagaagat aaagagaaaa agagggaaga     1620

attgaaaaaa attgttgaag aagagagact aaagaaaaaa gaagaaaaag agaggcttaa     1680

agtagaaaga gaaaaggaaa gagagaagtt acgtgaagaa aagcgaaagt atgtggaata     1740

cttaaaacag tggagtaaac ctagagaaga tatggaatgt gatgacctta aggaacttcc     1800

agaaccaaca ccagtgaaaa ctagactacc tcctgaaatc tttggtgatg ctctgatggt     1860

tttggagttc cttaatgcat ttggggaact ttttgatctt caagatgagt ttcctgatgg     1920

agtaacccta gaagtattag aggaagctct tgtaggaaat gacagtgaag gcccactgtg     1980

tgaattgctt tttttcttcc tgactgcaat cttccaggca atagctgaag aagaagagga     2040

agtagccaaa gagcaactaa ctgatgctga caccaaagat ttaacagagg ctttggatga     2100

agatgcagac cccacaaaat ctgcactgtc tgcagttgca tctttggcag ctgcatggcc     2160

acagttacac cagggctgca gtttgaaaag tttggatctt gatagctgca ctctttcaga     2220

aatcctcaga ctgcacatct tagcttcagg tgctgatgta acatcagcaa atgcaaagta     2280

tagatatcaa aaacgaggag gatttgatgc tacagatgat gcttgtatgg agcttcgttt     2340

gagcaatccc agtctagtga agaaactgtc aagcacctca gtgtatgatt tgacaccagg     2400

agaaaaaatg aagatactcc atgctctctg tggaaagcta ctgaccctag tttcaactag     2460

ggattttatt gaagattatg ttgatatatt acgacaggca aagcaggagt tccgggaatt     2520

aaaagcagaa caacatcgaa aagagaggga agaagcagct gccagaattc gtaaaaggaa     2580

ggaagaaaaa cttaaggagc aagaacaaaa aatgaaagag aaacaagaaa aactgaaaga     2640

agatgagcaa agaaattcaa cggcagatat atctattggg gaggaagaaa gggaagattt     2700

tgatactagc attgagagca aagacacaga gcaaaaggaa ttagatcaag atatggtcac     2760

tgaagatgaa gatgacccag gatcacataa aagaggcaga agggggaaaa gaggacaaaa     2820

tggatttaaa gaatttacaa ggcaagaaca gatcaactgt gtaacaagag agcctcttac     2880

tgctgatgag gaagaagcat taaaacagga acaccaacga aaagagaaag agctcttaga     2940

aaaaatccaa agtgccatag cctgtaccaa tatctttccc ttgggtcgcg accgcatgta     3000

tagacgatac tggattttcc cttctattcc tggactcttt attgaagagg attattctgg     3060

tcttactgaa gacatgctgt tgcctagacc ttcatcattt cagaataatg tacagtctca     3120

agatcctcag gtatccacta aaactggaga gcctttgatg tctgaatcta cctccaacat     3180

tgaccaaggt ccacgtgacc attctgtgca gctgccaaaa ccagtgcata agccaaatcg     3240

gtggtgcttt tacagttctt gtgaacagct agaccagctt attgaagctc ttaattctag     3300

aggacataga gaaagtgcct taaaagaaac tttgttacaa gagaaaagca gaatatgtgc     3360

acagctagcc cgtttttctg aagagaaatt tcatttttca gacaaacctc agcctgatag     3420

caaaccaaca tatagtcggg gaagatcttc caatgcatat gatccatctc agatgtgtgc     3480

agaaaagcaa cttgaactaa ggctgagaga ttttctttta gatattgaag atagaatcta     3540

ccaaggaaca ttaggagcca tcaaggttac agatcgacat atctggagat cagcattaga     3600

aagtggacgg tatgagctgt taagtgagga aaacaaggaa aatgggataa ttaaaactgt     3660

gaatgaagac gtagaagaga tggaaattga tgaacaaaca aaggtcatag taaaagacag     3720

acttttgggg ataaaaacag aaactccaag tactgtatca acaaatgcaa gtacaccaca     3780

atcagtgagc agtgtggttc attatctggc aatggcactc tttcaaatag agcagggcat     3840

tgagcggcgt tttctgaaag ctccacttga tgccagtgac agtgggcgtt cttataaaac     3900

agttctggac cgttggagag agtctctcct ttcttctgct agtctatccc aagtttttct     3960

tcacctatcc accttggatc gtagcgtgat atggtctaaa tctatactga atgcgcgttg     4020

caagatatgt cgaaagaaag gcgatgctga aaacatggtt ctttgtgatg gctgtgatag     4080

gggtcatcat acctactgtg ttcgaccaaa gctcaagact gtgcctgaag gagactggtt     4140

ttgtccagaa tgtcgaccaa agcaacgttc tagaagactc tcctctagac agagaccatc     4200

cttggaaagt gatgaagatg tggaagacag tatgggaggt gaggatgatg aagttgatgg     4260

cgatgaagaa gaaggtcaaa gtgaggagga agagtatgag gtagaacaag atgaagatga     4320

ctctcaagaa gaggaagaag tcagcctacc caaacgagga agaccacaag ttagattgcc     4380

agttaaaaca agagggaaac ttagctcttc tttctcaagt cgtggccaac aacaagaacc     4440

tggaagatac ccttcaagga gtcagcagag cacacccaaa acaactgttt cttctaaaac     4500

tggtagaagc ctaagaaaga taaactctgc tcctcctaca gaaacaaaat ctttaagaat     4560

tgccagtcgt tctactcgcc acagtcatgg cccactgcaa gcagatgtat ttgtggaatt     4620

gcttagtcct cgtagaaaac gcagaggcag gaaaagtgct aataatacac cagaaaatag     4680

tcccaacttc cctaacttca gagtcattgc cacaaagtca agtgaacagt caagatctgt     4740

aaatattgct tcaaaacttt ctctccaaga gagtgaatcc aaaagaagat gcagaaaaag     4800

acaatctcca gagccatcgc ctgtgacact gggtcgaagg agttctggcc gacagggagg     4860

agttcatgaa ttgtctgctt ttgaacaact tgttgtagaa ttggtacgac atgatgacag     4920

ctggcctttt ttgaaacttg tttctaaaat ccaggtccca gactactatg acatcatcaa     4980

aaagcccatt gccttaaata taattcgtga aaaagtgaat aagtgtgaat ataaattagc     5040

atctgagttt attgatgaca ttgagttaat gttttcgaac tgctttgaat acaaccctcg     5100

taacacaagt gaagcaaaag ctggaactag gcttcaagca ttttttcata ttcaggctca     5160

aaagcttgga ctccacgtca cacccagtaa tgtggaccaa gttagcacac caccggctgc     5220

gaaaaagtca cgaatctgac tttgtccttc taaaggatat atttgaagaa aaacaaattg     5280

ttcatgaaaa tggaacatta aatcatgctg tataaagcaa taacaattga ttgaccacat     5340

gaaagtgtgg cctgcactat attctcaatt ttaatattaa gcactcagga gaatgtagga     5400

aagatatcct ttgctacagt tttgttcagt atctaataag tttgatagat gtattggata     5460

cagtactggt ttacagaggt ttttgtacat ttttgagatc attcatgtgt ccagagatct     5520

tggaaaatat tttttcaccc acgatttatt ttgttattga tgattttttt ttaaagtggt     5580

ggtattaagg gagagttatc tacatggatg agtcttccgc tatagcacag tttagaaaag     5640

gtgtttatgt cttaattaat tgtttgagta cattctttca acactacaca tgaatgaatc     5700

caatcttata accttgaagt gctgtaccag tgctggctgc aggtattaag tccaagttta     5760

ttaactagat atttatttag tattgagagt aatttgtgaa tttgttttgt atttataaaa     5820

tttatacctg aaaaatgttc cttaatgttt taaacctttt actgtgtttt tattcctcta     5880

acttccttaa tgatcaatca aaaaaagtaa caccctccct ttttcctgac agttctttca     5940

gctttacaga actgtattat aagtttctat gtataacttt ttaactgtac aaataaaata     6000

acattttttc aaataaaaaa aaaaaaaaaa a                                    6031


<210>  2029
<211>  8516
<212>  DNA
<213>  homo sapiens

<400>  2029
gagtagctcc agcggccacg ctgaggcgag ggtgacacac catgctcacg gcccctggag       60

accgtcgtgc tggcgagccg tgctccgtag ctccccggtc cgcctcggca gcggtcagag      120

tcgcctacag gagttgagcc gcccgcgcca gaaggttttg gcgaagctct tggagaggcg      180

tcgagcacag tagggcggcg ggggtgcgtt gagcgctcgg gggtcaggca gtcggccggg      240

atcgccgctg gggagcgttt ccgaggcgag gaggaggagg aggagatgct gctcctcttc      300

tccccctccc caggctcctt ctacagctcc ttcagcccac gcccgcagcc gcttgtggga      360

gaagtggtgg tggctctcgg cgcccgcggc ggctgccggc ggcccgcccc gacgccgcgt      420

ccctgcagcc ctcgcccggc gctccagtag caggacccgg tctcgggacc agccggtaat      480

atgcacgtgt cactagctga ggccctggag gttcggggtg gaccacttca ggaggaagaa      540

atatgggctg tattaaatca aagtgctgaa agtctccaag aattattcag aaaagtaagc      600

ctagctgatc ctgctgccct tggcttcatc atttctccat ggtctctgct gttgctgcca      660

tctggtagtg tgtcatttac agatgaaaat atttccaatc aggatcttcg agcattcact      720

gcaccagagg ttcttcaaaa tcagtcacta acttctctct cagatgttga aaagatccac      780

atttattctc ttggaatgac actgtattgg ggggctgatt atgaagtgcc tcagagccaa      840

cctattaagc ttggagatca tctcaacagc atactgcttg gaatgtgtga ggatgttatt      900

tacgctcgag tttctgttcg gactgtgctg gatgcttgca gtgcccacat taggaatagc      960

aattgtgcac cctcattttc ctacgtgaaa cacttggtaa aactggttct gggaaatctt     1020

tctgggacag atcagctttc ctgtaacagt gaacaaaagc ctgatcgaag ccaggctatt     1080

cgagatcgat tgcgaggaaa aggattacca acaggaagaa gctctacttc tgatgtacta     1140

gacatacaaa agcctccact ctctcatcag acctttctta acaaagggct tagtaaatct     1200

atgggatttc tgtccatcaa agatacacaa gatgagaatt atttcaagga cattttatca     1260

gataattctg gacgtgaaga ttctgaaaat acattctccc cttaccagtt caaaactagt     1320

ggcccagaaa aaaaacccat ccctggcatt gatgtgcttt ctaagaagaa gatctgggct     1380

tcatccatgg acttgctttg tacagctgac agagacttct cttcaggaga gactgccaca     1440

tatcgtcgtt gtcaccctga ggcagtaaca gtgcggactt caactactcc tagaaaaaag     1500

gaggcaagat actcagatgg aagtatagcc ttggatatct ttggccctca gaaaatggat     1560

ccaatatatc acactcgaga attgcccacc tcctcagcaa tatcaagtgc tttggaccga     1620

atccgagaga gacaaaagaa acttcaggtt ctgagggaag ccatgaatgt agaagaacca     1680

gttcgaagat acaaaactta tcatggtgat gtctttagta cctccagtga aagtccatct     1740

attatttcct ctgaatcaga tttcagacaa gtgagaagaa gtgaagcctc aaagaggttt     1800

gaatccagca gtggtctccc aggggtagat gaaaccttaa gtcaaggcca gtcacagaga     1860

ccgagcagac aatatgaaac accctttgaa ggcaacttaa ttaatcaaga gatcatgcta     1920

aaacggcaag aggaagaact gatgcagcta caagccaaaa tggcccttag acagtctcgg     1980

ttgagcctat atccaggaga cacaatcaaa gcgtccatgc ttgacatcac cagggatccg     2040

ttaagagaaa ttgccctaga aacagccatg actcaaagaa aactgaggaa tttctttggc     2100

cctgagtttg tgaaaatgac aattgaacca tttatatctt tggatttgcc acggtctatt     2160

cttactaaga aagggaagaa tgaggataac cgaaggaaag taaacataat gcttctgaac     2220

gggcaaagac tggaactgac ctgtgatacc aaaactatat gtaaagatgt gtttgatatg     2280

gttgtggcac atattggctt agtagagcat catttgtttg ctttagctac cctcaaagat     2340

aatgaatatt tctttgttga tcctgactta aaattaacca aagtggcccc agagggatgg     2400

aaagaagaac caaagaaaaa gaccaaagcc actgttaatt ttactttgtt tttcagaatt     2460

aaatttttta tggatgatgt tagtctaata caacatactc tgacgtgtca tcagtattac     2520

cttcagcttc gaaaagatat tttggaggaa aggatgcact gtgatgatga gacttcctta     2580

ttgctggcat ccttggctct ccaggctgag tatggagatt atcaaccaga ggttcatggt     2640

gtgtcttact ttagaatgga gcactatttg cccgccagag tgatggagaa acttgattta     2700

tcctatatca aagaagagtt acccaaattg cataatacct atgtgggagc ttctgaaaaa     2760

gagacagagt tagaattttt aaaggtctgc caaagactga cagaatatgg agttcatttt     2820

caccgagtgc accctgagaa gaagtcacaa acaggaatat tgcttggagt ctgttctaaa     2880

ggtgtccttg tgtttgaagt tcacaatgga gtgcgcacat tggtccttcg ctttccatgg     2940

agggaaacca agaaaatatc tttttctaaa aagaaaatca cattgcaaaa tacatcagat     3000

ggaataaaac atggcttcca gacagacaac agtaagatat gccagtacct gctgcacctc     3060

tgctcttacc agcataagtt ccagctacag atgagagcaa gacagagcaa ccaagatgcc     3120

caagatattg agagagcttc gtttaggagc ctgaatctcc aagcagagtc tgttagagga     3180

tttaatatgg gacgagcaat cagcactggc agtctggcca gcagcaccct caacaaactt     3240

gctgttcgac ctttatcagt tcaagctgag attctgaaga ggctatcctg ctcagagctg     3300

tcgctttacc agccattgca aaacagttca aaagagaaga atgacaaagc ttcatgggag     3360

gaaaagccta gagagatgag taaatcatac catgatctca gtcaggcctc tctctatcca     3420

catcggaaaa atgtcattgt taacatggaa cccccaccac aaaccgttgc agagttggtg     3480

ggaaaacctt ctcaccagat gtcaagatct gatgcagaat ctttggcagg agtgacaaaa     3540

cttaataatt caaagtctgt tgcgagttta aatagaagtc ctgaaaggag gaaacatgaa     3600

tcagactcct catccattga agaccctggg caagcatatg ttctagatgt gctacacaaa     3660

agatggagca tagtatcttc accagaaagg gagatcacct tagtgaacct gaaaaaagat     3720

gcaaagtatg gcttgggatt tcaaattatt ggtggggaga agatgggaag actggaccta     3780

ggcatattta tcagttcagt tgcccctgga ggaccagctg acttggatgg atgcttgaag     3840

ccaggagacc gtttgatatc tgtgaatagt gtgagtctgg agggagtcag ccaccatgct     3900

gcaattgaaa ttttgcaaaa tgcacctgaa gatgtgacac ttgttatctc tcagccaaaa     3960

gaaaagatat ccaaagtgcc ttctactcct gtgcatctca ccaatgagat gaaaaactac     4020

atgaagaaat cttcctacat gcaagacagt gctatagatt cttcttccaa ggatcaccac     4080

tggtcacgtg gtaccctgag gcacatctcg gagaactcct ttgggccatc tgggggcctg     4140

cgggaaggaa gcctgagttc tcaagattcc aggactgaga gtgccagctt gtctcaaagc     4200

caggtcaatg gtttctttgc cagccattta ggtgaccaaa cctggcagga atcacagcat     4260

ggcagccctt ccccatctgt aatatccaaa gccaccgaga aagagacttt cactgatagt     4320

aaccaaagca aaactaaaaa gccaggcatt tctgatgtaa ctgattactc agaccgtgga     4380

gattcagaca tggatgaagc cacttactcc agcagtcagg atcatcaaac accaaaacag     4440

gaatcttcct cttcagtgaa tacatccaac aagatgaatt ttaaaacttt ttcttcatca     4500

cctcctaagc ctggagatat ctttgaggtt gaactggcta aaaatgataa cagcttgggg     4560

ataagtgtca cgggaggtgt gaatacgagt gtcagacatg gtggcattta tgtgaaagct     4620

gttattcccc agggagcagc agagtctgat ggtagaattc acaaaggtga tcgcgtccta     4680

gctgtcaatg gagttagtct agaaggagcc acccataagc aagctgtgga aacactgaga     4740

aatacaggac aggtggttca tctgttatta gaaaagggac aatctccaac atctaaagaa     4800

catgtcccgg taaccccaca gtgtaccctt tcagatcaga atgcccaagg tcaaggccca     4860

gaaaaagtga agaaaacaac tcaggtcaaa gactacagct ttgtcactga agaaaataca     4920

tttgaggtaa aattatttaa aaatagctca ggtctaggat tcagtttttc tcgagaagat     4980

aatcttatac cggagcaaat taatgccagc atagtaaggg ttaaaaagct ctttcctgga     5040

cagccagcag cagaaagtgg aaaaattgat gtaggagatg ttatcttgaa agtgaatgga     5100

gcctctttga aaggactatc tcagcaggaa gtcatatctg ctctcagggg aactgctcca     5160

gaagtattct tgcttctctg cagacctcca cctggtgtgc taccggaaat tgatactgcg     5220

cttttgaccc cacttcagtc tccagcacaa gtacttccaa acagcagtaa agactcttct     5280

cagccatcat gtgtggagca aagcaccagc tcagatgaaa atgaaatgtc agacaaaagc     5340

aaaaaacagt gcaagtcccc atccagaaga gacagttaca gtgacagcag tgggagtgga     5400

gaagatgact tagtgacagc tccagcaaac atatcaaatt cgacctggag ttcagctttg     5460

catcagactc taagcaacat ggtatcacag gcacagagtc atcatgaagc acccaagagt     5520

caagaagata ccatttgtac catgttttac tatcctcaga aaattcccaa taaaccagag     5580

tttgaggaca gtaatccttc ccctctacca ccggatatgg ctcctgggca gagttatcaa     5640

ccccaatcag aatctgcttc ctctagttcg atggataagt atcatataca tcacatttct     5700

gaaccaacta gacaagaaaa ctggacacct ttgaaaaatg acttggaaaa tcaccttgaa     5760

gactttgaac tggaagtaga actcctcatt accctaatta aatcagaaaa aggaagcctg     5820

ggttttacag taaccaaagg caatcagaga attggttgtt atgttcatga tgtcatacag     5880

gatccagcca aaagtgatgg aaggctaaaa cctggggacc ggctcataaa ggttaatgat     5940

acagatgtta ctaatatgac tcatacagat gcagttaatc tgctccgggc tgcatccaaa     6000

acagtcagat tagttattgg acgagttcta gaattaccca gaataccaat gttgcctcat     6060

ttgctaccgg acataacact aacgtgcaac aaagaggagt tgggtttttc cttatgtgga     6120

ggtcatgaca gcctttatca agtggtatat attagtgata ttaatccaag gtccgtcgca     6180

gccattgagg gtaatctcca gctattagat gtcatccatt atgtgaacgg agtcagcaca     6240

caaggaatga ccttggagga agttaacaga gcattagaca tgtcacttcc ttcattggta     6300

ttgaaagcaa caagaaatga tcttccagtg gtccccagct caaagaggtc tgctgtttca     6360

gctccaaagt caaccaaagg caatggttcc tacagtgtgg ggtcttgcag ccagcctgcc     6420

ctcactccta atgattcatt ctccacggtt gctggggaag aaataaatga aatatcgtac     6480

cccaaaggaa aatgttctac ttatcagata aagggatcac caaacttgac tctgcccaaa     6540

gaatcttata tacaagaaga tgacatttat gatgattccc aagaagctga agttatccag     6600

tctctgctgg atgttgtgga tgaggaagcc cagaatcttt taaacgaaaa taatgcagca     6660

ggatactcct gtggtccagg tacattaaag atgaatggga agttatcaga agagagaaca     6720

gaagatacag actgcgatgg ttcaccttta cctgagtatt ttactgaggc caccaaaatg     6780

aatggctgtg aagaatattg tgaagaaaaa gtaaaaagtg aaagcttaat tcagaagcca     6840

caagaaaaga agactgatga tgatgaaata acatggggaa atgatgagtt gccaatagag     6900

agaacaaacc atgaagattc tgataaagat cattcctttc tgacaaacga tgagctcgct     6960

gtactccctg tcgtcaaagt gcttccctct ggtaaataca cgggtgccaa cttaaaatca     7020

gtcattcgag tcctgcgggg tttgctagat caaggaattc cttctaagga gctggagaat     7080

cttcaagaat taaaaccttt ggatcagtgt ctaattgggc aaactaagga aaacagaagg     7140

aagaacagat ataaaaatat acttccctat gatgctacaa gagtgcctct tggagatgaa     7200

ggtggctata tcaatgccag cttcattaag ataccagttg ggaaagaaga gttcgtttac     7260

attgcctgcc aaggaccact gcctacaact gttggagact tctggcagat gatttgggag     7320

caaaaatcca cagtgatagc catgatgact caagaagtag aaggagaaaa aatcaaatgc     7380

cagcgctatt ggcccaacat cctaggcaaa acaacaatgg tcagcaacag acttcgactg     7440

gctcttgtga gaatgcagca gctgaagggc tttgtggtga gggcaatgac ccttgaagat     7500

attcagacca gagaggtgcg ccatatttct catctgaatt tcactgcctg gccagaccat     7560

gatacacctt ctcaaccaga tgatctgctt acttttatct cctacatgag acacatccac     7620

agatcaggcc caatcattac gcactgcagt gctggcattg gacgttcagg gaccctgatt     7680

tgcatagatg tggttctggg attaatcagt caggatcttg attttgacat ctctgatttg     7740

gtgcgctgca tgagactaca aagacacgga atggttcaga cagaggatca atatattttc     7800

tgctatcaag tcatccttta tgtcctgaca cgtcttcaag cagaagaaga gcaaaaacag     7860

cagcctcagc ttctgaagtg acatgaaaag agcctctgga tgcatttcca tttctctcct     7920

taacctccag cagactcctg ctctctatcc aaaataaaga tcacagagca gcaagttcat     7980

acaacatgca tgttctcctc tatcttagag gggtattctt cttgaaaata aaaaatattg     8040

aaatgctgta tttttacagc tactttaacc tatgataatt atttacaaaa ttttaacact     8100

aaccaaacaa tgcagatctt agggatgatt aaaggcagca tttgatgata gcagacattg     8160

ttacaaggac atggtgagtc tatttttaat gcaccaatct tgtttatagc aaaaatgttt     8220

tccaatattt taataaagta gttattttat aggggatact tgaaaccagt atttaagctt     8280

taaatgacag taatattggc atagaaaaaa gtagcaaatg tttactgtat caatttctaa     8340

tgtttactat atagaatttc ctgtaatata tttatatact ttttcatgaa aatggagtta     8400

tcagttatct gtttgttact gcatcatctg tttgtaatca ttatctcact ttgtaaataa     8460

aaacacacct taaaacatga acaagccaaa actgtgtgca gacaaaaaaa aaaaaa         8516


<210>  2030
<211>  3278
<212>  DNA
<213>  homo sapiens

<400>  2030
aatagactaa acccagagcc tcaaagcagt gcactccgtg aaggcaaaga gaacacgctg       60

caaaaggctt tccaagaatc ctcgacatgg caaggaggag ctcgttccag tcgtgtcaga      120

taatatccct gttcactttt gccgttggag tcaatatctg cttaggattc actgcacatc      180

gaattaagag agcagaagga tgggaggaag gtcctcctac agtgctatca gactccccct      240

ggaccaacat ctccggatct tgcaagggca ggtgctttga acttcaagag gctggacctc      300

ctgattgtcg ctgtgacaac ttgtgtaaga gctataccag ttgctgccat gactttgatg      360

agctgtgttt gaagacagcc cgtggctggg agtgtactaa ggacagatgt ggagaagtca      420

gaaatgaaga aaatgcctgt cactgctcag aggactgctt ggccagggga gactgctgta      480

ccaattacca agtggtttgc aaaggagagt cgcattgggt tgatgatgac tgtgaggaaa      540

taaaggccgc agaatgccct gcagggtttg ttcgccctcc attaatcatc ttctccgtgg      600

atggcttccg tgcatcatac atgaagaaag gcagcaaagt catgcctaat attgaaaaac      660

taaggtcttg tggcacacac tctccctaca tgaggccggt gtacccaact aaaacctttc      720

ctaacttata cactttggcc actgggctat atccagaatc acatggaatt gttggcaatt      780

caatgtatga tcctgtattt gatgccactt ttcatctgcg agggcgagag aaatttaatc      840

atagatggtg gggaggtcaa ccgctatgga ttacagccac caagcaaggg gtgaaagctg      900

gaacattctt ttggtctgtt gtcatccctc acgagcggag aatattaacc atattgcagt      960

ggctcaccct gccagatcat gagaggcctt cggtctatgc cttctattct gagcaacctg     1020

atttctctgg acacaaatat ggccctttcg gccctgagga gagtagttat ggctcacctt     1080

ttactccggc taagagacct aagaggaaag ttgcccctaa gaggagacag gaaagaccag     1140

ttgctcctcc aaagaaaaga agaagaaaaa tacataggat ggatcattat gctgcggaaa     1200

ctcgtcagga caaaatgaca aatcctctga gggaaatcga caaaattgtg gggcaattaa     1260

tggatggact gaaacaacta aaactgcatc ggtgtgtcaa cgtcatcttt gtcggagacc     1320

atggaatgga agatgtcaca tgtgatagaa ctgagttctt gagtaattac ctaactaatg     1380

tggatgatat tactttagtg cctggaactc taggaagaat tcgatccaaa tttagcaaca     1440

atgctaaata tgaccccaaa gccattattg ccaatctcac gtgtaaaaaa ccagatcagc     1500

actttaagcc ttacttgaaa cagcaccttc ccaaacgttt gcactatgcc aacaacagaa     1560

gaattgagga tatccattta ttggtggaac gcagatggca tgttgcaagg aaacctttgg     1620

atgtttataa gaaaccatca ggaaaatgct ttttccaggg agaccacgga tttgataaca     1680

aggtcaacag catgcagact gtttttgtag gttatggctc aacatttaag tacaagacta     1740

aagtgcctcc atttgaaaac attgaacttt acaatgttat gtgtgatctc ctgggattga     1800

agccagctcc taataatggg acccatggaa gtttgaatca tctcctgcgc actaatacct     1860

tcaggccaac catgccagag gaagttacca gacccaatta tccagggatt atgtaccttc     1920

agtctgattt tgacctgggc tgcacttgtg atgataaggt agagccaaag aacaagttgg     1980

atgaactcaa caaacggctt catacaaaag ggtctacaga agagagacac ctcctctatg     2040

ggcgacctgc agtgctttat cggactagat atgatatctt atatcacact gactttgaaa     2100

gtggttatag tgaaatattc ctaatgccac tctggacatc atatactgtt tccaaacagg     2160

ctgaggtttc cagcgttcct gaccatctga ccagttgcgt ccggcctgat gtccgtgttt     2220

ctccgagttt cagtcagaac tgtttggcct acaaaaatga taagcagatg tcctacggat     2280

tcctctttcc tccttatctg agctcttcac cagaggctaa atatgatgca ttccttgtaa     2340

ccaatatggt tccaatgtat cctgctttca aacgggtctg gaattatttc caaagggtat     2400

tggtgaagaa atatgcttcg gaaagaaatg gagttaacgt gataagtgga ccaatcttcg     2460

actatgacta tgatggctta catgacacag aagacaaaat aaaacagtac gtggaaggca     2520

gttccattcc tgttccaact cactactaca gcatcatcac cagctgtctg gatttcactc     2580

agcctgccga caagtgtgac ggccctctct ctgtgtcctc cttcatcctg cctcaccggc     2640

ctgacaacga ggagagctgc aatagctcag aggacgaatc aaaatgggta gaagaactca     2700

tgaagatgca cacagctagg gtgcgtgaca ttgaacatct caccagcctg gacttcttcc     2760

gaaagaccag ccgcagctac ccagaaatcc tgacactcaa gacatacctg catacatatg     2820

agagcgagat ttaactttct gagcatctgc agtacagtct tatcaactgg ttgtatattt     2880

ttatattgtt tttgtattta ttaatttgaa accaggacat taaaaatgtt agtattttaa     2940

tcctgtacca aatctgacat attatgcctg aatgactcca ctgtttttct ctaatgcttg     3000

atttaggtag ccttgtgttc tgagtagagc ttgtaataaa tactgcagct tgagttttta     3060

gtggaagctt ctaaatggtg ctgcagattt gatatttgca ttgaggaaat attaattttc     3120

caatgcacag ttgccacatt tagtcctgta ctgtatggaa acactgattt tgtaaagttg     3180

cctttatttg ctgttaactg ttaactatga cagatatatt taagccttat aaaccaatct     3240

taaacataat aaatcacaca ttcagttttt tctggttt                             3278


<210>  2031
<211>  2118
<212>  DNA
<213>  homo sapiens

<400>  2031
acccgggggg ccgcgctgcg cggagtgcca ggctgcgggc ggctgcagac ctgggagcgg       60

agaccggccc gccgcccccg acgccgccga gcacgtcagc ggcgcgcagc cggggctcgg      120

agaccgacgg gcagaacgac gggcggcgac tgcggcgacc gcgggacggc gagaggcacg      180

cggcgggagg ggaccggaat ccgcagctcc ggccgcgcca tggacggcaa cgacaacgtg      240

accctgctct tcgcccctct gctgcgggac aactacaccc tggcgcccaa tgccagcagc      300

ctgggccccg gcacggacct cgccctcgcc cctgcctcca gcgccggccc cggccctggg      360

ctcagcctcg ggccgggtcc gagcttcggc ttcagccccg gccccactcc gaccccggag      420

cccacgacca gcggcctcgc gggcggcgcg gcgagccacg gcccttcccc gttccctcgg      480

ccctgggcgc cccacgcgct cccgttctgg gacacgccgc tgaaccacgg gctgaacgtg      540

ttcgtgggcg ccgccctgtg catcaccatg ctgggcctgg gctgcacggt ggacgtgaac      600

cacttcgggg cgcacgtccg tcggcccgtg ggcgcgctgc tggcagcgct ctgccagttc      660

ggcctcctgc cgctgctggc cttcctgctg gccctcgcct tcaagctgga cgaggtggcc      720

gccgtggcgg tgctcctgtg tggctgctgt cccggcggca atctctccaa tcttatgtcc      780

ctgctggttg acggcgacat gaacctcagc atcatcatga ccatctcctc cacgcttctg      840

gccctcgtct tgatgcccct gtgcctgtgg atctacagct gggcttggat caacacccct      900

atcgtgcagt tactacccct agggaccgtg accctgactc tctgcagcac tctcatacct      960

atcgggttgg gcgtcttcat tcgctacaaa tacagccggg tggctgacta cattgtgaag     1020

gtttccctgt ggtctctgct agtgactctg gtggtccttt tcataatgac cggcactatg     1080

ttaggacctg aactgctggc aagtatccct gcagctgttt atgtgatagc aatttttatg     1140

cctttggcag gctacgcttc aggttatggt ttagctactc tcttccatct tccacccaac     1200

tgcaagagga ctgtatgtct ggaaacaggt agtcagaatg tgcagctctg tacagccatt     1260

ctaaaactgg cctttccacc gcaattcata ggaagcatgt acatgtttcc tttgctgtat     1320

gcacttttcc agtctgcaga agcggggatt tttgttttaa tctataaaat gtatggaagt     1380

gaaatgttgc acaagcgaga tcctctagat gaagatgaag atacagatat ttcttataaa     1440

aaactaaaag aagaggaaat ggcagacact tcctatggca cagtgaaagc agaaaatata     1500

ataatgatgg aaaccgctca gacttctctc taaatgtgga gatacacagg agcttctatc     1560

ttgctgaaat attgcttcat atttatagcc tgtggtagtg cacatggtta acataaaaga     1620

taacactggt tcacatcata catgtaacaa ttctgatctt tttaaggttc actggtgtat     1680

taaccaaacg ttgtcacaaa ttacaaatca atgctgtaat ataatttgca cctggaatgg     1740

ctaacgtgaa gcctgaatta aatgtggttt ttagttttta ccatcaccaa tttctatgac     1800

tgttgcaaat acagaatcta ttagaaaaca gggtcttgga aatgtagaat tttggcgcac     1860

tatgaggaaa aacaagctat ctttgtaaag cataattgag tttaatgtaa ttgttgtaaa     1920

aaaaaaagtg tgcttgctct acttaaaatt cctcacaatg ttgaattttg acctgtattc     1980

agaagaattc caaaacaggt cagttaaata aggaaatata gtatttgtca aaccagtatc     2040

agagaaaagt tacattaatg tatttgatta cttgatctgg tatctactta ttaatgaata     2100

atcaacattt ttctagtg                                                   2118


<210>  2032
<211>  8133
<212>  DNA
<213>  homo sapiens

<400>  2032
agcggaccga gccgcagccg cagccgggcg gcgggcgaga ggcggcggcg gcgggcgggc       60

cgcgggcagt cagtcgggcg gcggcggcgg cggcggcggc ggcgatgcgg cggccccgct      120

gagtccgccc gctcctggcg ccgggagcca gccgcgcgag gcggcccggg ccgggcggca      180

gcatgcggag cggcgaggag ctggacggct tcgagggcga ggcctcgagc acctccatga      240

tctcgggcgc cagcagcccg taccagccca ccaccgagcc ggtgagccag cgccgcgggc      300

tggccggcct gcgctgcgac cccgactacc tgcgcggcgc gctcggccgc ctcaaggtcg      360

cccaagtgat cttggccctg attgcattca tctgcataga gaccatcatg gcatgctccc      420

cgtgtgaagg cctctacttt tttgagtttg tgagctgcag tgcgtttgtg gtgactggcg      480

tcttgctgat tatgttcagt ctcaacctgc acatgaggat cccccagatc aactggaatc      540

tgacagattt ggtcaacact ggactcagcg ctttcctttt ctttattgct tcaatcgtac      600

tggctgcttt aaaccataga gccggagcag aaattgctgc cgtgatattt ggcttcttgg      660

cgactgcggc atatgcagtg aacacattcc tggcagtgca gaaatggaga gtcagcgtcc      720

gccagcagag caccaatgac tacatccgag cccgcacgga gtccagggat gtggacagtc      780

gccctgagat ccagcgcctg gacacgtgag gacctgcctg gatcctcctc cctcccgtcc      840

tcgtgcctgt ctctcagtca agttttcttt cccttgtcct gtcagatttc catgtgattc      900

agttgaattt tgtcctcttt ggtaaaagtt cattttggga aagggtttcc cgagtggccc      960

agtgggcggg tccgcggtgg agttgggagg cccacgttcc tcagcgtttg gggctgtgga     1020

gcagccggcg tcactgccca ggtccacttg aggtcttacc tgccctgaag cacaggcttc     1080

ctttgactct gagccacctt gtcgtgtgta tttgtaacaa gactttggat taaatggggc     1140

tgctaagagg ggggaaatat gaaggaatga agggacagca ttggaacggt cagtcggcag     1200

tggttctcag gcagccttag gcaccacctg ctccaagtca gtgttgagtc tgcgtgctgg     1260

gatccagccc actcctcatc ttccatgcca gggcccccag gcagccagca ccagcccaaa     1320

ggccacaggg ctggggaaag ctgatgtcct gttaggatgg ctcccaggga cctctgactc     1380

aaggaagggt gaccttttgt ttcctactct gctgagaaat cacttgattc ttcctcaaat     1440

gaatcacctt cctgaacccc agattcttct ccaggaatat gggggccatc ttgttatggg     1500

gactatcttg ttttccagtt tcctgcctac cctaaatact ttgaggctga attgcagatt     1560

ttcagtcatt ttaccttctc aggtaaaagc catgaaagaa acaagcctac tccaccagcc     1620

aaagcacttg cccatttgct ggcttcatga accgcaggtg ggaggtgttt gtgttaaaaa     1680

acagcatgca cacgcgtgcg cgcacacatg cacacacaca cccctctatt ttagggatgt     1740

gtgctaattt tctaaatgcc tgcaaagagt tctaaaatga ttctgagcag attcgtctag     1800

gatttgaaaa tacttgaatt tgcaccagaa cacacccttc cacccatgtt tcagaaggca     1860

ctaattgtcg ctttgggcgc ctcagtgtca taactgtaga catcattctt gggagttgtt     1920

ggggggaaaa atcctagcta cttaaggttt ctgattgatt cttgataaag tgaagattat     1980

tgtgtgtggt gaatgagttc agtgagtccc catgatgcag tagttttttt aaaaaattag     2040

agagtaatta tatcttttat ggaaaaaagt tgttttagtt tgtcaggttt tccctctttg     2100

aactgttttt aatgtttaca aacctcactt tagctctaac attttgtgtt tagccctcac     2160

caaaaagcac ttactgtggc aggaagattt tgcagtaaca tggagaaatc cccaagatca     2220

agtgctgaca aatgttgaca gctttagcag cgtactgtgt aataaataac tccgaggggg     2280

cggcgggggg tctgtgcaag aaagcgtcac cttatggaca tgtggcgtct cattccccag     2340

aaaaggacag catctgagct cacagtgttg atcaggcaac actgctgggc tgggggtcgg     2400

agttggggtt agcttcctgc accaacacct tcagtacgat ctgagttggg agcagtgtcc     2460

caggctatgt ggctgagcac cacgtctgcc tcaggggctg accctgctag cctgttaaca     2520

actcgtctcc cctctgctcc cacagagagg gcagccaggc cagctcacag ctgggtgtgc     2580

tgcctgtcag gtctgttgag tgtgtttgca aagtcaaaat tgggcttatc tctctttgag     2640

agttcctttt aaaatagggc cacaaaggct cagccttgca ttaaatgggg cccacttgga     2700

aggaccatcc tgagctttat cagaaatctc ctgctgggaa tcatgttact tggcccccaa     2760

aaaaggccat ctttgaagtg agattgaaaa caagaacacc attcaggtgg gcttgttgcc     2820

caagttttcc cagctcactt cagtaaaacc acttgatcat ctggtgaaag aggggggcag     2880

gtggttggcc tcctgaggat atgttgtcag ctgcaagaaa tagttctgaa gtcactgaaa     2940

ctaaatgcag atgaatgacc aaaaaggatg acacgccaga gagtgactta ggagttaatt     3000

tgcatcttcg tgatagactc ttcagaatta tttatgtccc tgtaactatt taatatcctt     3060

tgtgccgtga ggctcctcgg tggttttgta aatgttctcc ttgtatttaa ttaactccca     3120

ctagaaccgg aagtggtgct atggacgctt tctagttgat gtaatgtgtg gttgcacatg     3180

tcatcatgta tagaccacgt ggtgacgaaa gttctggagg gaatagggtt atccaaggtg     3240

aatatgaaga cgcctatatt tttcttatat tgcctctata tgcaaacaga agacaatcga     3300

tatctggggg ccttaaaatg acctcttggc aaattgaagg aagcgttttt gcgtttaata     3360

gtttcaatag ggaccaatat cagtttggtt tggggcattt gaaggctgag cgaccttagt     3420

ttttctcagt gttctggtgg gacgatattg gttttcacat ttaaagcaaa acttgaagaa     3480

actgcagttg ctgtgtgcat ttgggttttt tcctggacac tgtacagctg aaaccctcaa     3540

gcatttggtg gaacctctgg tggttttaga tggatgcaaa cactgatgtc ctcagagaaa     3600

gtttattttg gcactgattg ggtggatttg gtattttttc cctctgattc tctttgatat     3660

ccttctttca cactgctgaa ggcatgggag ggaaatatgt tttccctgcc ttaaagaggg     3720

attacagtca tgaaaggctg gagatacttg ttggccccac ataaagctgg gaagaacaga     3780

tgcagtttca gattaaaatc tcgtcagaga agtttgattt gaagtaaaca gccatccgag     3840

ggaggtgact tttgtctaca gaaaaagcaa gaatgtggca gcctgcacag ccccaataca     3900

catcttcctt ggcaatgtga gctgaagcca gcatgggcaa gtccggccca gctctgagcg     3960

cttggccctg ggaagccagc ggcaccccca gcccttcggg ccctgttact gtcccctggc     4020

aggaaggctc acgcctgtgg gcagccaggg aatgtgtctg acctccaccc tatgtcgggt     4080

gcttctggga cagcttcgtg actcagttga aaacattctg actctcttca agtttgcagt     4140

tacatctgtg gttcttggaa gctgtcctag tgagtcagcc ttgggttaag cctgaggaga     4200

ccaagctcca acacctttgt gcactcatgt acgtgaattc ttgcttgcag tgaatgagac     4260

ctgaacaacc ctagtgggtg ccatgtcctg cgtgtggccc aggcgtacct tttcttgtag     4320

attcacatga gaaacccgtc acctatccat gtgctctgag aggtggactg aggtctaatc     4380

cctttctgtg ccagattttc tgtgggttgg tcttagcacc taggagatga atagagcatg     4440

gagacacctg aacaatttag tgattctgca aggcagtgat gatttaaggg ttcctattgt     4500

ctcatctgtg ttcaaaacaa aacagtcatg aagtctttgt gccactgcct gactgtcatc     4560

ttctccagat cttgtttaca gagtaataat gacgttaaac aggtatcaga aaggggaaaa     4620

agtttctagg ccaagagctg ctggtggatt ctcttgagca gaataacaag ttgcttcctg     4680

ctccagggac tgccattagc ttgtgaagtc tctaggtgcc ttgttatttc ctagtgaagt     4740

tgcagaatcc agggtttttt ccaggtttgt cttattttat cagcacccac gtccaggccc     4800

aacagcttgg taggctggtg aggtccacac acggccaggt ctgggagata agggaggaag     4860

cagtggcctg gaacacccca cctgtctgct atcagcacta gacagctcag gctgtcttgg     4920

aaacgtgtac tttgttaact gccttcctgt cctcttgtct ttgaaagctg tctcgcgttc     4980

cacagtcagc ttgagggcaa gagtgggatg ctggggacag gtctttcccg tcctgtgggt     5040

gagctcctgg catctggctc aggaacatgt gggtccagca ggtgactctg aagctggctt     5100

ggctgccatc tcagacagga cgcaggcctg acaccctcag cttttagctt tgtaaacttc     5160

cctggcgctt tgtagaatct tgtgtttctt ctcttctcag cagatatcat tcaagtcaca     5220

agaactgtct ggttgagaaa gtaatttaaa atatttgacc ttttatgttt cttttattta     5280

gaaactgtga gagaaaatac cgtcaatatc tgttaggtct agaaaaattt tcttccgaaa     5340

gtgaatgttc tgtttaattc ttcttcatgc aagtgagtgg cattttgtac actctttagc     5400

ttgaagcgga gtgggtccta ttgtattttc ccttcttttg tctggaatat attctttttc     5460

catttggata cagtttttca acctttggga tttttttttc ctttctagtt tttcctactc     5520

cacaaacgta acagtaagga aaaaatcacc cacaaacctg ctgagtttga atcactggca     5580

acttgcctag aaaagttcag atgatgggtc cttgaactgt gtatctattt catagggtaa     5640

gtttgttgtc tatgtttgtt tttttatgct gaggctttaa ttcaggtgac ttgctatcta     5700

gacacctggg gtggcgtgtt ttctttggga tgcataatac acaaaggcca gggagccttt     5760

ggcttggacc cccagggagc tattgaaact tttaaagttt gagtttagga gtaagaacat     5820

atctcagacc accttagtca gctttgctga tgggatttag ggccaggtca gagtttcttt     5880

tcataactgc ctgaaaagag agatggtgtg aaacaagatt ctgataatgg tttgtgtgag     5940

atttgatcat agtctaaaac tatcacgtct gagttgcctt aggatgacag tgctgacacc     6000

cagtaggaag tatcccattt ttatcaggaa agtcagtcac gcgtagggat ggtgaggaga     6060

cgcgtaggga tggtgaggag gggagaggag ggagacctgc tggtgccctt gcaccagggt     6120

gaggcctgac tcacgctgct tccccccaca ggccctgctt tgcttgcctg ctttttccag     6180

aatcgatttt gcaagcttca agattctgtt cccctcttcg cagaagtgag gaaggcaaat     6240

actcagggtt tgaagggaga cctggccggc ctgagggctg gcagatgtga gggcaggaca     6300

cctgggatgg actcgtaggc tgacccaggc ccaaaggggg ctgcctgttc ccaactcttt     6360

cactctgtaa cccattttaa aatgagtttt tgaatcttgc ctcaaattga cctacttgga     6420

taaaatcagt gcttttccta acttgatttt gtttgacgtg gttccctcta agagaatggt     6480

aggaattgaa actatttgta tatgttgaaa tttgtagggg ttcaggaacc catggcagaa     6540

acactaaact atttatttac aagtatgact attttttttt caaagtaggc aattctttgt     6600

atattttaag gcaaataatc acttcacctc tggtgccttc catgcgtcgc ataagcactc     6660

ttgtcaatca tggaattgga aaaaaagatg tacatttagt taaacaagat aacactattt     6720

ttgtagcatg attttagatt gtgtcctttt aatattgttt tcaacaatgg tagttttgag     6780

gttttggcca ttttctcttt acacttcgta tgtattttaa agaagaaaaa aaacaaaaaa     6840

aattccctgg ctattcctct ttcctctctg ctgctgcttc tcctgcatct tgttcctgct     6900

tatttaaata gtctgagagt aagagtatat ttctgtgaaa taattataag tcagtataat     6960

tgcatttggc attttttaac cacttgctca gtttggagcc actgctcacc tcaaacagta     7020

caaagaaagt ggttccatat tttacaaaca gaagagtagc atcagagccc tgacctcctg     7080

tctttgggtg taaaatggtg agaggccggt gtccggctcc ttcccctgtg gtttgggctg     7140

gtgaactgag cccaagtgta ttctctggcc tgggcccctt ccagaatcag tgcgagcgtc     7200

ctgcagaggc atggccttcc tgccactgca gagtgggaag cttcctgggg gacctcagcc     7260

agctccgggg ctctcatctt ccactcggat ctcagattgg ttcgttgtgg atgctctggc     7320

taggctcggc ggccttttcc aggcttcagg cctgaacaaa acaggctgtt tgctgtgagg     7380

agctagatga caccaagaca cagacacgta ctcttcaccg gctccttttg cttctccttc     7440

ctgcaggacg tgagttatgt ctggtcccaa aacccttgag taaactagct gagccattgc     7500

aaatgaaggt acagatggat tgaaacataa aattgtagct tttggtgtcc ttctgaaggg     7560

tcagaatatg taattatttg ataaccaagg aagtcaagtc agatggctaa gtagtaactt     7620

tccaatatga tttctccgtg gtacttcacc tggtggcact tttggggggc aatgttaaca     7680

actatcacat tttactcatc aagtctcttt catttcggca gtttaaagac acaactgtgg     7740

gctttctgag gcgatgcccg ttgggcaaac ttaggtttat gtgtttggtt tttcagctga     7800

cgtggaagcc ctgggtgggc gtcccctggc tggcctggct tttgggttca agtctgtatg     7860

tatggagtgg gttggggccc caaagctttg ctgctattga tttgtccccg acagcaggca     7920

aagcctcaca ttgccctcaa ttttccccct ttcatttgaa ggaccagttt ttcatggtac     7980

ttgtcttgat ctttttcata gtgttcaaat ctgtattttt gtatgtagag ggaaataatt     8040

ttctcaacac taatcgttaa taactattgt attaaattgt catgaaggaa cttgtttaat     8100

aaatggacgt gtaaggaaaa aaaaaaaaaa aaa                                  8133


<210>  2033
<211>  4079
<212>  DNA
<213>  homo sapiens

<400>  2033
gagggggcgg ggaggcgcgg gcgggtgtgc gcgcgccggg cgtgggtgtg ggtgggggta       60

accggcgcgg gcgccgagat agcgccgggc agagggaccc ggctaccctg gacagcgcat      120

cgccgcccgc ccgggtcgcc gcgccacagc cgctgcggat catggaacat ctaaaggcct      180

ttgatgatga aatcaatgct tttttggaca atatgtttgg accgcgagat tctcgagtca      240

gagggtggtt catgttggac tcttaccttc ctaccttttt tcttactgtc atgtatctgc      300

tctcaatatg gctgggtaac aagtatatga agaacagacc tgctctttct ctcaggggta      360

tcctcacctt gtataatctt ggaatcacac ttctctccgc gtacatgctg gcagagctca      420

ttctctccac ttgggaagga ggctacaact tacagtgtca agatcttacc agcgcagggg      480

aagctgacat ccgggtagcc aaggtgcttt ggtggtacta tttctccaaa tcagtagagt      540

tcctggacac aattttcttc gttttgcgga aaaaaacgag tcagattact tttcttcatg      600

tatatcatca tgcttctatg tttaacatct ggtggtgtgt cttgaactgg ataccttgtg      660

gacaaagttt ctttggacca acactgaaca gttttatcca cattcttatg tactcctact      720

atggactttc tgtgtttcca tctatgcaca agtatctttg gtggaagaaa tatctcacac      780

aggctcagct ggtgcagttc gtgctcacca tcacgcacac catgagcgcc gtcgtgaaac      840

cgtgtggctt ccccttcggt tgtctcatct tccagtcatc ttatatgcta acgttagtca      900

tcctcttctt aaatttttac gttcagacat accgaaaaaa gccaatgaag aaagatatgc      960

aagagccacc tgcagggaaa gaagtgaaga atggtttttc caaagcctac ttcactgcag     1020

caaatggagt gatgaacaag aaagcacaat aaaaatgagt aacagaaaaa gcacatatac     1080

tagcctaaca gattggcttg ttttaaagca aagactgaat tgaaggttac atgttttagg     1140

ataaactaat ttcttttgag ttcataaatc atttgtaccc agaatgtatt aatatattgc     1200

tattaggtta atctgttaac tgaatgcttt gatcagcatt gaggtgatgc tcacctccga     1260

ggacctcaga actggtgcag cttctctctc cctccctccc acagactgaa cctttcgcca     1320

gaagctgtcc ttataacgcc ttatacgcat acacagccag gaaacgtgga gcattgtttc     1380

tcacagagag tctccaaata aaaagggttt tgttcagatt aaaatgttta caacaaaatg     1440

ttaattatat tctaaataca gggtatgttc taatctatat taagcaataa tgccagtgca     1500

taatcattcc atttgttcct ttagcaatca accccagaaa atattaaaat gggatcatac     1560

acagaagata gaaaaatcta gcaaaacttc tctttctgta agccagagtc ttgtctatca     1620

gattcccaca accactcctg attctaaatt tagtgatatg gtaatgaaat tggtatttat     1680

tttaaatatt agttattcta aggagaaaaa aatgcttctg caagattttc ataattcagg     1740

ggctgtggat aggattgttc ctctgtttcc ctaatcattc atctgttcat gtctccctct     1800

tgtgccagtc agcctaggtt atacagatgc catgctccac accacgagca gtgtacaaat     1860

ctggctgccc gtttactttc tgagcaagca ctggagtcca ctccgacctt tttctttgaa     1920

catgcatgct gctggaatat gtataaatca gaactagcag aagtagcaga gtgatgggag     1980

caaaataggc actgaattcg tcaactcttt tttgtgagcc tacttgtgaa tattacctca     2040

gatacctgtt gtcactcttc acaggttatt taagtttttg aagctgggag gaaaaagatg     2100

gagtagcttg gaaagattcc agcactgagc cgtgggccgg tcatgagcca cgataaaaaa     2160

tgccagtttg gcaaactcag cactcctgtt ccctgctcag gtatatgcga tctctaccga     2220

gaagcaagca caaaagtaga caaaagtatt aatgagtatt tcctttctcc ataagtgcag     2280

gactgttact cactactaaa ctctaccaag aatggaaaca aagaatattt tctgaagatt     2340

tttttgaaga ttaatttata ccctataaaa taaaacttgt tagcttcgat gaagtcactt     2400

catcttctct cctgccttat ttttttaaat aagtttttag gtcctgacac tgacatcaaa     2460

tacatgcaca ccagaaaggc atttccacca ccgtccccac tcattagcgt ccagagtgcc     2520

tttctctctc ggcttttttt cccccctgag ctctagtttt aaactttctc ctgttaaaaa     2580

aattgtactt ttatttcatg taaactgccc ctctgaggat ttgggcatat tttttggaag     2640

gtgcctaatg cttaggatag tctctagggt gatgcactgc acctgcttcc ttcccttcag     2700

tgcggccgac ccatttctgt tgaacagatg tctcctgtgt gatgcccctg actcttacat     2760

ttatctttct aaatcatttt ctgaagctga cttgctctag ggtgcttcat caccacttcc     2820

atcttgcatc accttataac tgttctgtct tgttctctcc cagcaattta ttttaaaaca     2880

agggctagct tcaagcatga ctgttaatgg ctcctctgtg acaaaacaca agttggacca     2940

aggagaaagc cctttggaga aactggaccc tagttcagtt tagatctcaa atataggctg     3000

aaatctctta ccaaagtgcg ttccagataa aaatgagact tagaagacag actggtctaa     3060

tatgctcact ggtcatcaca ttcagcttat tcttacgtgc cagtgaggcc ctaaggtctc     3120

agtgcatagc atacctgcca ctctggatgt tttcctgggc ttcatatctg tatggcaagg     3180

agggagctgt ccttcagcag acaaagtcaa gcagctttaa gtacaaggca gcttgaaacc     3240

tctctgatga aagtgaaaaa tgtgggtagc ttatactttc aaactaatgc cagtgactag     3300

agagaggttt cattcatgat gtgtatttcc aatttggtct tcaattcaag agatgcttca     3360

taaaacactt atagccttaa accattcaag ggctaattaa aaaaatagtt atgaaatctt     3420

agccacaaaa aataaatcag gtaaacattt taacctgtcg ttaagtgttg taacttcaaa     3480

aaaccaaaat gcttatttta atgtgatttt tctaaaacta ttgaaaaatt aatatttcta     3540

taatctatta aaaaaaatgg agaatgtttt ctctcaaatt tcctctgacc catgggaatg     3600

aaaatactta aatactgtaa agcatatcta ttaataattc ccccaatttt ttaaactaac     3660

aaaatggaat gttaactgaa tggaattaaa catagcaatt gtcaagccat caaaattata     3720

tatcgaacca cttaggcatg ttacggggta aagtcctcac ccctgcattt gagaaatatt     3780

ttattatttt tattttaagg caaaacagtg tttactgtga tgggcagaac agccttttgt     3840

atctaggagt ccatttgagt tctttccaat atttccatat cgttcataaa tgtgtctggg     3900

ggcttccttg tttggaaaat atggatatcg ctttgttttc ctttgaaagt aattatatct     3960

taagaacata gtatcatgaa tggagtagac agggaggctg cagaagccat ttctctttgt     4020

agataaaaag cattatctat gattgttgta taataaattg atttttacat taaaaaaaa      4079


<210>  2034
<211>  3534
<212>  DNA
<213>  homo sapiens

<400>  2034
agtcaagagg cggggaggag aggaggaaaa agcgctgagt gagggcgggc gggcgggcgg       60

gagggaggga gtggaggagc cggggagggg ctccttaaag aaacgcttct gtcgctcgcc      120

tgctcgcttt tcgctcggca ttgcggccag ccagccgggc actcgggggg cacgcgcggc      180

caccgctaga gctctgcccc caccccaccc gccagcaggt ctggggtggg gacccaggtg      240

ggggctcctg cagccactgc ccggtgcgga ccgcacggag cgacccactc ctcccagcac      300

cgaggaagaa gcaacggagc cctcagcagg cgaccggcct ccccgcccct gaccacccgc      360

ttcccggctg cctttgtggc cgcagcttct cgccgccgag ccgagggccg gcgggggcgc      420

ggcgcgcacg gccgagcgat gcccagctcg ctgttcgcag acctggagcg caacggcagc      480

ggcggcggcg gcggcggcag cagcggaggg ggagagaccc tggatgacca aagagccctg      540

cagctcgcgc tcgaccagct ctccctgctg gggctggaca gtgacgaggg cgcctctctg      600

tacgacagcg agccgcgcaa gaagagcgtg aacatgaccg agtgcgtgcc agtacccagt      660

tctgagcatg tcgccgagat cgtggggcgg caaggttgta aaatcaaagc gctgcgggcg      720

aagaccaata cttacatcaa gaccccagtt cgcggggagg agcctgtctt tgttgtgacg      780

ggcaggaagg aggatgtggc catggctcgg agggagatca tctctgctgc cgagcacttc      840

tccatgatcc gcgcctcccg gaataagaac acggcactca acggcgcggt gcctgggccg      900

cccaacctgc ccgggcagac caccatccaa gtgcgggtac cctaccgcgt ggtggggctc      960

gtggtggggc ccaaaggcgc cacaatcaag cgcatccagc agcagacgca cacgtacatc     1020

gtgacgccca gccgggataa ggagccggtg ttcgaggtga ccggcatgcc agagaacgtg     1080

gatcgcgctc gagaggagat tgaggcgcac attgctctgc gtaccggcgg catcattgag     1140

ctcacagacg agaacgactt ccacgccaac ggcaccgatg tgggcttcga tctgcatcat     1200

gggtccggcg ggtccggccc aggcagcctc tggagcaagc ccacccccag catcacgccc     1260

acccccggcc gcaagccttt ctctagctac cgcaacgaca gctccagctc gcttggcagt     1320

gcttccacag actcttattt cggcggcggg accagcagca gcgcagcggc tacccagcgc     1380

ctggcggact acagcccccc tagccccgcc ctgagctttg cgcacaacgg aaacaataac     1440

aataacggca atgggtacac ctacacagcg gggggagaag cctcagtgcc atcccccgac     1500

ggctgccccg agctgcagcc cacttttgac ccggctcccg ctcccccacc tggggcacca     1560

cttatctggg cccagttcga gcggtccccg ggaggcggac ctgcagctcc ggtatcttct     1620

tcctgctctt cttctgcatc ttcgtctgct tcttcctcct ccgtggtctt ccccgggggt     1680

ggcgccagtg cgccctccaa cgccaacctg gggctattgg tgcaccgccg gctgcaccct     1740

ggcaccagct gcccgcgcct gtctccaccc ttgcacatgg ccccgggggc gggagagcac     1800

cacctggctc gccgggtgcg cagcgacccg ggtggaggag gcctggccta cgccgcttat     1860

gccaacgggc tgggggcaca gctgcctggc ttgcagccgt cggacacgtc gggctcctcc     1920

tcttcgtcca gctcctcctc cagctcttca tcctcttcct ccgggcttcg gcgtaaaggc     1980

agccgcgact gctccgtgtg cttcgagagc gaagtgattg ccgcgctggt gccctgtggc     2040

cacaacctct tctgcatgga gtgcgccaat cgcatctgtg agaagagcga gcccgagtgc     2100

ccggtctgcc acaccgcggt cactcaggcc atccgcatct tttcttaaag gcagcgggcg     2160

ctgctagtgc gcaccgtgct gggggaaggg ggaacccctc cccatcctct ttccccagcg     2220

ctcgcctgcc tccctgggtg ccccccctct cccttctcct tcccggcccc accaacactc     2280

tgagatccga gaggagcttg gaaagctgta gtatccgctc atttttaaaa tttaattttt     2340

aagtaaagga atttgccagg atatctgcat caagagtact gtagcctggg aaacctgaac     2400

acctgaaatg catgctctat aaataatagg aacggcgaca ttctagtaat gatagttttt     2460

acactgtact taataggaag cttccaaaag aagaaaaccc cacaagtttt ccattttctt     2520

aaagtaggaa aaaatgaaca gtaataatta tgatgaagat gatagtagtg ctatgggatg     2580

tgtggactgt ttagtgtgtt cccctttgtg ggtgggttcc tatgatactt attatagaac     2640

acagtggatc ctttttgaat gttcgtggaa gggccaggag ttcctgtgaa accaggatac     2700

tgcagcttta ttaaagttaa agaaactgta acatatctct tatatattaa aaacgtttaa     2760

aagttttaaa gagaaattgc attaatacag attgaagtat tttattcttt tttgacttga     2820

aaaattatat ttcatattgc aaagatgttt acaagtattt taatttaagt tcagtgaact     2880

tttttgtagc tgggttaaat ctttttattt tagtatggcc ttatggcaaa gaacactgta     2940

ttattttaat aatcacacaa ttgtgacgga attacaacca taaaatgtgt aatgttttga     3000

acagtattct gttgggatgg agattttata ggttcagaca aatcttctag atctgcttca     3060

cccagcatat tttctattca gtgatataaa gcatatttta ttctatatta ttacaaaaac     3120

ggaaatgtat aaacatgtca aaaagaactg ttgatgcttt ctaacatttg tataaataga     3180

attcagtgca agttacaaaa attctgttgc accactctag ttttagtatt tctattttaa     3240

tacatttgtt taccacttgt ttatgtatat gtaggtgatg ttacttgagc ttaaatgtac     3300

tttactgagc aaagtttaaa aaacaaagta tattttattt tatgataaag ggcctttaac     3360

ctcatggtca aatactaata ttatatttgc tgagacaaga tttgaaattg tatcaagagt     3420

tttatttttc tgacatttaa agttctacat aataaaggta aaacttaagt aatggtgcta     3480

cttcattttt taagtatttc tatataaata aaatattgaa gaaaatctta aaaa           3534


<210>  2035
<211>  2404
<212>  DNA
<213>  homo sapiens

<400>  2035
tgaggccagg agatggaggc tgcagtgagc tgtgatcaca ccactgtgct ccagcctgag       60

tgacagagca agaccctatc tcaaaaaaaa aaaaaaaaaa gaaaagctcc tgaggtgtag      120

acgccaactc tctctagctc gctagtgggt tgcaggaggt gcttacgcat gtttgtttct      180

ttgctgccgt cttccagttg ctttatctgt tcacttgtgc cctgactttc aactctgtct      240

ccttcctctt cctacagtac tcccctgccc tcaacaagat gttttgccaa ctggccaaga      300

cctgccctgt gcagctgtgg gttgattcca cacccccgcc cggcacccgc gtccgcgcca      360

tggccatcta caagcagtca cagcacatga cggaggttgt gaggcgctgc ccccaccatg      420

agcgctgctc agatagcgat ggtctggccc ctcctcagca tcttatccga gtggaaggaa      480

atttgcgtgt ggagtatttg gatgacagaa acacttttcg acatagtgtg gtggtgccct      540

atgagccgcc tgaggttggc tctgactgta ccaccatcca ctacaactac atgtgtaaca      600

gttcctgcat gggcggcatg aaccggaggc ccatcctcac catcatcaca ctggaagact      660

ccagtggtaa tctactggga cggaacagct ttgaggtgcg tgtttgtgcc tgtcctggga      720

gagaccggcg cacagaggaa gagaatctcc gcaagaaagg ggagcctcac cacgagctgc      780

ccccagggag cactaagcga gcactgccca acaacaccag ctcctctccc cagccaaaga      840

agaaaccact ggatggagaa tatttcaccc ttcaggacca gaccagcttt caaaaagaaa      900

attgttaaag agagcatgaa aatggttcta tgactttgcc tgatacagat gctacttgac      960

ttacgatggt gttacttcct gataaactcg tcgtaagttg aaaatattat ccgtgggcgt     1020

gagcgcttcg agatgttccg agagctgaat gaggccttgg aactcaagga tgcccaggct     1080

gggaaggagc caggggggag cagggctcac tccagccacc tgaagtccaa aaagggtcag     1140

tctacctccc gccataaaaa actcatgttc aagacagaag ggcctgactc agactgacat     1200

tctccacttc ttgttcccca ctgacagcct cccaccccca tctctccctc ccctgccatt     1260

ttgggttttg ggtctttgaa cccttgcttg caataggtgt gcgtcagaag cacccaggac     1320

ttccatttgc tttgtcccgg ggctccactg aacaagttgg cctgcactgg tgttttgttg     1380

tggggaggag gatggggagt aggacatacc agcttagatt ttaaggtttt tactgtgagg     1440

gatgtttggg agatgtaaga aatgttcttg cagttaaggg ttagtttaca atcagccaca     1500

ttctaggtag gggcccactt caccgtacta accagggaag ctgtccctca ctgttgaatt     1560

ttctctaact tcaaggccca tatctgtgaa atgctggcat ttgcacctac ctcacagagt     1620

gcattgtgag ggttaatgaa ataatgtaca tctggccttg aaaccacctt ttattacatg     1680

gggtctagaa cttgaccccc ttgagggtgc ttgttccctc tccctgttgg tcggtgggtt     1740

ggtagtttct acagttgggc agctggttag gtagagggag ttgtcaagtc tctgctggcc     1800

cagccaaacc ctgtctgaca acctcttggt gaaccttagt acctaaaagg aaatctcacc     1860

ccatcccaca ccctggagga tttcatctct tgtatatgat gatctggatc caccaagact     1920

tgttttatgc tcagggtcaa tttctttttt cttttttttt tttttttttc tttttctttg     1980

agactgggtc tcgctttgtt gcccaggctg gagtggagtg gcgtgatctt ggcttactgc     2040

agcctttgcc tccccggctc gagcagtcct gcctcagcct ccggagtagc tgggaccaca     2100

ggttcatgcc accatggcca gccaactttt gcatgttttg tagagatggg gtctcacagt     2160

gttgcccagg ctggtctcaa actcctgggc tcaggcgatc cacctgtctc agcctcccag     2220

agtgctggga ttacaattgt gagccaccac gtccagctgg aagggtcaac atcttttaca     2280

ttctgcaagc acatctgcat tttcacccca cccttcccct ccttctccct ttttatatcc     2340

catttttata tcgatctctt attttacaat aaaactttgc tgccacctgt gtgtctgagg     2400

ggtg                                                                  2404


<210>  2036
<211>  3033
<212>  DNA
<213>  homo sapiens

<400>  2036
gctttctttg tgtggctgaa gcgctagaaa tggcatattt tctttccctt cgttaaaaaa       60

tcagaccctc tttcccctct ctccccgcgg gaacacagct agggagtggg taggagcagg      120

atctgccgac gagggcagag gcggaaaatc ctcgggcgat gagctgaaga gggccgggtc      180

cgggagggat gctgggagct tgactcactc gcacaccatg tgtccctccg cgcgcagcac      240

gggggacttt tcggtgggga ttttgggcgc cgaccagacg cggcattttc ggaaaatagc      300

gccctgtgca gctgaagcgc tttgtgtgta gcggggccgc gtcagcccgg ccgggtacga      360

ggcgcctcgg gtccccgcac cacctcctgc tgccttcccg tcgccgctcc cgaagctttt      420

ccagatgtcc ctggtagatt tgggaaagaa gcttttagaa gcggcacgag caggtcaaga      480

tgatgaagtt cgtattttga tggcaaatgg agctcccttt actacagact ggctgggaac      540

ttctccactt catctagcag cacagtatgg tcattattcc accacagagg tactgctgcg      600

agctggtgtg agcagagatg ccagaaccaa agtggaccga acaccattac atatggcagc      660

ttctgagggc catgccagca tagtagaggt tttacttaag catggtgctg atgtcaatgc      720

aaaggacatg ttaaagatga cagctctcca ttgggccaca gaacacaatc atcaagaggt      780

ggtggaactt ttaatcaaat atggtgctga tgtacacacg caaagtaaat tttgtaaaac      840

tgcatttgat atttcaatag acaatggaaa tgaagattta gcagagatat tacagattgc      900

tatgcagaac caaatcaaca caaacccaga gagtcctgac actgtgacaa tacatgctgc      960

aacaccacag tttatcattg gacctggagg ggtggtgaac ctaacagatg aaacgggtgt     1020

atctgctgtt cagtttggaa actcttctac atcagtatta gctacattag ctgccttagc     1080

tgaagcatct gctccattgt ccaattcttc agaaactcca gtagtggcca cagaagaagt     1140

agttactgca gaatctgtgg atggtgccat tcagcaagta gttagttcag ggggtcagca     1200

agtcatcaca atagttacag atggaattca gcttggaaat ttgcactcta ttccaaccag     1260

tggaattggt cagcccatca ttgtgaccat gccagatgga caacaagtat taacagtacc     1320

agcaacagac attgctgaag aaactgttat aagtgaagaa ccaccagcta agagacaatg     1380

tatcgaaata attgaaaacc gggtggaatc tgcagaaata gaagagagag aagctcttca     1440

gaaacagctg gatgaagcaa atcgagaagc acaaaaatat cgacagcagc tcctaaagaa     1500

agaacaggaa gcagaggcct acagacagaa gttggaagct atgactcgtc ttcagactaa     1560

taaagaagct gtttaattga aatgaacatg tagtttgatt ttacttttgg tcaagaaaga     1620

atacaatctt gaactgtaca caacaaaggt acagccatgg gaatacagaa tgatagaaga     1680

gactacagat ggataattgg acttaagcca tgagctctga gttcttgtaa cataaaactt     1740

tactttagaa gttgtgaaat gtatttaaaa ctgaattctg taaatagttt tttttttttt     1800

acagttccaa atgagttgat aaagattgtt gaagagatcc aaaaccagaa taagccactg     1860

tttttgtgaa ttctttttga ttttagtaca aaccttaatt tctcagaaac ggaacagttt     1920

taagggtgat cgttgttggt taggccaaat gttgtgtaat aattatggtg gactgatgct     1980

ggaattactc ctgtaggtat aaacctctgt atgaagagaa gatttctccc aggaaatctt     2040

tgtacagctt taagttgtgt cagattctct gaaaacattt tttagaaagc aaaattttta     2100

tatttgttca atttcagcta tacccaagta gatttacatg tatatgaagc aaatattttt     2160

aaaaatttct gtttgtacat attctgcatg ttttataatt tcaaaatgca tcacttacat     2220

aggtatttct cccacagaaa tgatgaaagt gaccagaaaa aaacaaaaac aaaacccctt     2280

tactctgtag gtcattgaaa cgaagtaagc tggcagctgg ttttattgga atgacagtgt     2340

tctcggaagg agcagcctac aagataactt gaatttgcca attctgcaaa atctgtgctt     2400

ttttgaaaat ttaagagtgg ggacgtgaaa ctgtattctg tgccttccat catgatttcc     2460

acatgaaagc actttaaggc actgatttta agataatgtt tttggaaaac ccaatgcata     2520

tgggtttctg aaatatttta tggacttatt tctccccagg aaatgattct tacggaaaaa     2580

aattgctttt gtatgtagaa caggaacttt ttgtattaca gtgatgcaat agacatgtct     2640

aatgtaactt ctacttttcc ttttgaaagc tcagtgtctg tgctatgact tgctctcatc     2700

acaatattgt tgaattccac aatgtatgga cattaaacac tggcagactg ttcacttttt     2760

cttttttttt tttggtaaaa tattacttca aacccctttt tcttgcttta tttttcagtg     2820

ttttattgct ttatgaactg tttaaccctg aaatccctct aggttatcta tactgtataa     2880

aaaagcaatt acccttaaaa ctgtactctg gcctactttt ctattttgca attaaatatc     2940

tttttcacat atgttcattg tagacttatg tttttatcac atcttattaa cacattaaaa     3000

atgttatcct actgcaaaaa aaaaaaaaaa aaa                                  3033


<210>  2037
<211>  3069
<212>  DNA
<213>  homo sapiens

<400>  2037
gctttctttg tgtggctgaa gcgctagaaa tggcatattt tctttccctt cgttaaaaaa       60

tcagaccctc tttcccctct ctccccgcgg gaacacagct agggagtggg taggagcagg      120

atctgccgac gagggcagag gcggaaaatc ctcgggcgat gagctgaaga gggccgggtc      180

cgggagggat gctgggagct tgactcactc gcacaccatg tgtccctccg cgcgcagcac      240

gggggacttt tcggtgggga ttttgggcgc cgaccagacg cggcattttc ggaaaatagc      300

gccctgtgca gctgaagcgc tttgtgtgta gcggggccgc gtcagcccgg ccgggtacga      360

ggcgcctcgg gtccccgcac cacctcctgc tgccttcccg tcgccgctcc cgaagctttt      420

ccagatgtcc ctggtagatt tgggaaagaa gcttttagaa gcggcacgag caggtcaaga      480

tgatgaagtt cgtattttga tggcaaatgg agctcccttt actacagact ggctgggaac      540

ttctccactt catctagcag cacagtatgg tcattattcc accacagagg tactgctgcg      600

agctggtgtg agcagagatg ccagaaccaa agtggaccga acaccattac atatggcagc      660

ttctgagggc catgccagca tagtagaggt tttacttaag catggtgctg atgtcaatgc      720

aaaggacatg ttaaagatga cagctctcca ttgggccaca gaacacaatc atcaagaggt      780

ggtggaactt ttaatcaaat atggtgctga tgtacacacg caaagtaaat tttgtaaaac      840

tgcatttgat atttcaatag acaatggaaa tgaagattta gcagagatat tacagattgc      900

tatgcagaac caaatcaaca caaacccaga gagtcctgac actgtgacaa tacatgctgc      960

aacaccacag tttatcattg gacctggagg ggtggtgaac ctaacaggtc tggtatcttc     1020

agaaaattca tccaaggcaa cagatgaaac gggtgtatct gctgttcagt ttggaaactc     1080

ttctacatca gtattagcta cattagctgc cttagctgaa gcatctgctc cattgtccaa     1140

ttcttcagaa actccagtag tggccacaga agaagtagtt actgcagaat ctgtggatgg     1200

tgccattcag caagtagtta gttcaggggg tcagcaagtc atcacaatag ttacagatgg     1260

aattcagctt ggaaatttgc actctattcc aaccagtgga attggtcagc ccatcattgt     1320

gaccatgcca gatggacaac aagtattaac agtaccagca acagacattg ctgaagaaac     1380

tgttataagt gaagaaccac cagctaagag acaatgtatc gaaataattg aaaaccgggt     1440

ggaatctgca gaaatagaag agagagaagc tcttcagaaa cagctggatg aagcaaatcg     1500

agaagcacaa aaatatcgac agcagctcct aaagaaagaa caggaagcag aggcctacag     1560

acagaagttg gaagctatga ctcgtcttca gactaataaa gaagctgttt aattgaaatg     1620

aacatgtagt ttgattttac ttttggtcaa gaaagaatac aatcttgaac tgtacacaac     1680

aaaggtacag ccatgggaat acagaatgat agaagagact acagatggat aattggactt     1740

aagccatgag ctctgagttc ttgtaacata aaactttact ttagaagttg tgaaatgtat     1800

ttaaaactga attctgtaaa tagttttttt ttttttacag ttccaaatga gttgataaag     1860

attgttgaag agatccaaaa ccagaataag ccactgtttt tgtgaattct ttttgatttt     1920

agtacaaacc ttaatttctc agaaacggaa cagttttaag ggtgatcgtt gttggttagg     1980

ccaaatgttg tgtaataatt atggtggact gatgctggaa ttactcctgt aggtataaac     2040

ctctgtatga agagaagatt tctcccagga aatctttgta cagctttaag ttgtgtcaga     2100

ttctctgaaa acatttttta gaaagcaaaa tttttatatt tgttcaattt cagctatacc     2160

caagtagatt tacatgtata tgaagcaaat atttttaaaa atttctgttt gtacatattc     2220

tgcatgtttt ataatttcaa aatgcatcac ttacataggt atttctccca cagaaatgat     2280

gaaagtgacc agaaaaaaac aaaaacaaaa cccctttact ctgtaggtca ttgaaacgaa     2340

gtaagctggc agctggtttt attggaatga cagtgttctc ggaaggagca gcctacaaga     2400

taacttgaat ttgccaattc tgcaaaatct gtgctttttt gaaaatttaa gagtggggac     2460

gtgaaactgt attctgtgcc ttccatcatg atttccacat gaaagcactt taaggcactg     2520

attttaagat aatgtttttg gaaaacccaa tgcatatggg tttctgaaat attttatgga     2580

cttatttctc cccaggaaat gattcttacg gaaaaaaatt gcttttgtat gtagaacagg     2640

aactttttgt attacagtga tgcaatagac atgtctaatg taacttctac ttttcctttt     2700

gaaagctcag tgtctgtgct atgacttgct ctcatcacaa tattgttgaa ttccacaatg     2760

tatggacatt aaacactggc agactgttca ctttttcttt tttttttttg gtaaaatatt     2820

acttcaaacc cctttttctt gctttatttt tcagtgtttt attgctttat gaactgttta     2880

accctgaaat ccctctaggt tatctatact gtataaaaaa gcaattaccc ttaaaactgt     2940

actctggcct acttttctat tttgcaatta aatatctttt tcacatatgt tcattgtaga     3000

cttatgtttt tatcacatct tattaacaca ttaaaaatgt tatcctactg caaaaaaaaa     3060

aaaaaaaaa                                                             3069


<210>  2038
<211>  4566
<212>  DNA
<213>  homo sapiens

<400>  2038
agagtgaaaa aggcgagcca ccaaaaccca tctccagtct cctcccgggg gcccccagcc       60

cgcctctgtg ccactttgca tcccacgccg gaggaggcat taacgagacc gggtaaggct      120

ttttaaacgg tccaaggtgt agagccatac ttcaggagga tcctcagaag ttttggacaa      180

gcctccccaa atgtggcagg tgctgtgctg gccattggtg acccaaagat gatgaaaaat      240

atgttcctgc ccacaaggag ttagcgacct actgggcttt cctcttgctg atgacatgat      300

tcctgtttga atctgttgac aagattctga aagctgaaca gagaattctg gcactgcact      360

gggtaggaaa aaggatgtct tccaagcgac cagcctctcc gtatggggaa gcagatggag      420

aggtagccat ggtgacaagc agacagaaag tggaagaaga ggagagtgac gggctcccag      480

cctttcacct tcccttgcat gtgagttttc ccaacaagcc tcactctgag gaatttcagc      540

cagtttctct gctgacgcaa gagacttgtg gccataggac tcccacttct cagcacaata      600

caatggaagt tgatggcaat aaagttatgt cttcatttgc cccacacaac tcatctacct      660

cacctcagaa ggcagaagaa ggtgggcgac agagtggcga gtccttgtct agtacagccc      720

tgggaactcc tgaacggcgc aagggcagtt tagctgatgt tgttgacacc ttgaagcaga      780

ggaaaatgga agagctcatc aaaaacgagc cggaagaaac ccccagtatt gaaaaactac      840

tctcaaagga ctggaaagac aagcttcttg caatgggatc ggggaacttt ggcgaaataa      900

aagggactcc cgagagctta gctgagaaag aaaggcaact catgggtatg atcaaccagc      960

tgaccagcct ccgagagcag ctgttggctg cccacgatga gcagaagaaa ctagctgcct     1020

ctcagattga gaaacagcgt cagcaaatgg agctggccaa gcagcaacaa gaacaaattg     1080

caagacagca gcagcagctt ctacagcaac aacacaaaat caatttgctc cagcaacaga     1140

tccaggttca aggtcagctg ccgccattaa tgattcccgt attccctcct gatcaacgga     1200

cactggctgc agctgcccag caaggattcc tcctccctcc aggcttcagc tataaggctg     1260

gatgtagtga cccttaccct gttcagctga tcccaactac catggcagct gctgccgcag     1320

caacaccagg cttaggccca ctccaactgc agcagttata tgctgcccag ctagctgcaa     1380

tgcaggtatc tccaggaggg aagctgccag gcatacccca aggcaacctt ggtgctgctg     1440

tatctcctac cagcattcac acagacaaga gcacaaacag cccaccaccc aaaagcaagg     1500

atgaagtggc acagccactg aacctatcag ctaaacccaa gacctctgat ggcaaatcac     1560

ccacatcacc cacctctccc catatgccag ctctgagaat aaacagtggg gcaggccccc     1620

tcaaagcctc tgtcccagca gcgttagcta gtccttcagc cagagttagc acaataggtt     1680

acttaaatga ccatgatgct gtcaccaagg caatccaaga agctcggcaa atgaaggagc     1740

aactccgacg ggaacaacag gtgcttgatg ggaaggtggc tgttgtgaat agtctgggtc     1800

tcaataactg ccgaacagaa aaggaaaaaa caacactgga gagtctgact cagcaactgg     1860

cagttaaaca gaatgaagaa ggaaaattta gccatgcaat gatggatttc aatctgagtg     1920

gagattctga tggaagtgct ggagtctcag agtcaagaat ttatagggaa tcccgagggc     1980

gtggtagcaa tgaaccccac ataaagcgtc caatgaatgc cttcatggtg tgggctaaag     2040

atgaacggag aaagatcctt caagcctttc ctgacatgca caactccaac atcagcaaga     2100

tattgggatc tcgctggaaa gctatgacaa acctagagaa acagccatat tatgaggagc     2160

aagcccgtct cagcaagcag cacctggaga agtaccctga ctataagtac aagcccaggc     2220

caaagcgcac ctgcctggtg gatggcaaaa agctgcgcat tggtgaatac aaggcaatca     2280

tgcgcaacag gcggcaggaa atgcggcagt acttcaatgt tgggcaacaa gcacagatcc     2340

ccattgccac tgctggtgtt gtgtaccctg gagccatcgc catggctggg atgccctccc     2400

ctcacctgcc ctcggagcac tcaagcgtgt ctagcagccc agagcctggg atgcctgtta     2460

tccagagcac ttacggtgtg aaaggagagg agccacatat caaagaagag atacaggccg     2520

aggacatcaa tggagaaatt tatgatgagt acgacgagga agaggatgat ccagatgtag     2580

attatgggag tgacagtgaa aaccatattg caggacaagc caactgataa gggtcaaaag     2640

attgttgtga ccttaggact taaagaagcc ctaactggtt catccttacc agtggccaag     2700

cacattaact ttctcataca ctgactgtta ctttaactgt tagtcttaaa tagttgggac     2760

atcagctgac taatagacct cagcctcaaa aggcttggaa agaaaaaaca aatacaacaa     2820

gcaaacaaca atatcaacaa caagagattg aaataagcta tgggtaaaat aatgccagta     2880

attcagctgc tacatccaag cactgaagtc ttacccgtca actttttttt ttttttaaat     2940

aaactttatg gctgtttgtt ctacaatgtt ctagaaattc tcactcaggt acacagtgcc     3000

aacaagtggc ttgtgaatgt gttttgttgt tttgtgctac aatttttaaa aagaaaaaag     3060

ttttgttttg ttttttgggg tttctgggtt ttttcctttt ctttttcttt cctttcattt     3120

tttttctttg taatgcacct gacagaaaaa aaagaaaaat gaatttctct ttacttctct     3180

ccaccttctc catctctcta ctttaaagat ggaagtctgt gcatgagggg aaagagggaa     3240

aaagagcctg tttttaactt ccttgctatc caccacaaaa taagcaatta ttttctttag     3300

aggactttat ctattgcaca ccacactaca tctttgagca agtgccaaat ttgtactgaa     3360

gtgttgacca agttcatttt ttctctttac tttttccttt tccttcttaa gttaggacag     3420

tgttaaatct tagacaatcc cttgaaaaac ctgaaatacc agcagctggt gagatttgac     3480

tttttttttt aatggaaact gtaggtgctg ttctcaggtg aaaagagaga gagagagaga     3540

gacataagaa atttagagaa aaatattttc tgatcttgga tttttgtgtg tatgtatgta     3600

tgtgattatg gtactaataa taggaataac gttggaccat tgtgagttaa acccacatct     3660

ggggatgaaa tcccacatcc tcccaagtga ctggtctaga aataatcttg accttgactt     3720

tgcacttcaa atgacaactt aaccaagtat agggctcaga aattatattt ttaaatgtct     3780

gattattatt ggatggatca ggtggccctg tgtaatagag gtgtgcatgt ataacatgga     3840

agctactagc aaactgctcc cagatgtcct ttctccctgg tcagttggtt ccattaacgt     3900

ttgctactta gtgatttttg tttttcctgt tgatattttg agcaaaacaa tcattgtttt     3960

cattgaatat atttggccat tttttcagac aaatagaatt agcttatttc ttcaacattc     4020

catcctttcc cgatcaggaa atgaaactga tgattttata aggtattttt cacccctcca     4080

tgaagtgagg tggaggcctt tagcatttca gaagtgtggg ccatatgtag ttcatgccat     4140

aaaaagtagg atttaattaa aagtcattgc agcccaataa aatggagcct ggctgcaccc     4200

agggatcctt gccactgctc ttcccttgct gtcagattaa tccactgaag tccaactttg     4260

gttcaagcag agtatttgca aagagcaaca actgaatgtg atgggactgc ttatgtagat     4320

tttgccagcc aaatgccaag gcagttgtag ggcctgtaca aataaatgca aaatcatttc     4380

aagtcaattg ccattatttg tattgaagta tcagatagat agtaaatact gcaactagta     4440

gcttgatgtg ctatagtttt cactccagtc atcattttcc tatctcaccc cccgaaacac     4500

caccctaaag ttggattttt acatataaat aaaaaaagaa tcccttttaa aaaaaaaaaa     4560

aaaaaa                                                                4566


<210>  2039
<211>  2180
<212>  DNA
<213>  homo sapiens

<400>  2039
aggaggcggt gcgtgcctcg cctgccaaag ggagatccgc tcctctgcgt gcgatccccg       60

gcgcccgcgc gcgcccacag cgctccgcca gagctgccgc cgcggactcg ccgggagtgg      120

gggtctccgc tggtgccagc ccgcttctgg agaccctccg cctcctgcca acccctgctc      180

ttccaggtcg ggccccgggg ttctgcggct gttagggaca gaggcaaaga agggcaggac      240

ggtccggttt cccgtggatg ttcccgcccg agaaagacag caagttgtgt gtgcgcccgg      300

gacgcgggag ggaaggtagc cgccgcccgc cagccatgga ccatcatctt tagtgcagag      360

gatggaaagt tgatgcccag taagactgaa gatccattct gcattacgga actgtggatt      420

atctgtgggt ccctggtgat ttcacacctt cattcactcc tgcagtccct gaacacttac      480

ttggggtcct cattgcccta tctggtgaaa gatggcatcc agcctgactt gtactggagt      540

aatctgggct ttgctgtctt ttctttgtgc tgccacctcc tgcgtggggt tctttatgcc      600

ttactggctc tggggatcac agctgggcaa gcctgtgtcc ttcggtacct tccggaggtg      660

ctcatatcct gtgcatgatg agagtcggca gatgatggtg atggtggagg aatgtgggcg      720

ctatgcctcc ttccagggca tccccagcgc agaatggagg atctgcacca tagtgaccgg      780

cctgggttgt ggcctcctcc tcctggtggc gctcactgcc ctcatgggtt gctgtgtttc      840

cgacctcatc tccaggacag tgggaagagt ggctggagga attcagtttc ttgggggctt      900

gttgattggt gctggctgtg ccctctaccc cttgggctgg gacagtgagg aagtccggca      960

gacttgtggc tacacttctg gccagtttga cctggggaag tgtgaaatcg gctgggccta     1020

ctactgcacg ggagcaggtg ccactgccgc catgctgctg tgcacgtggc tggcttgctt     1080

ttcgggcaag aaacagaagc actacccata ctgagatgga gctaccaaga gcagacagag     1140

gagaagatgg gccaaagggg cttggagagg tcaaaacatc cacctacctt caaaaggtgg     1200

gatagtagtt ctaatccaat acaatgctaa taaaatgaaa cccgataaaa tcaggaacat     1260

gatataggaa ggaaggattg taggagattt gtgggggaaa aaaaaggaga gtatagaatg     1320

atggagaaaa atggaccaaa ggctaaaaat attgcagggc atcgggtgtt tctattccac     1380

agagtattgt taatgtacaa cacacacaca cacacacaca cacacacaca cacacacaca     1440

cacacaacaa atctacatat acaaacaagg gtttgggttt tagttttttt tttttaaggt     1500

gaggactcag aaaatcaaag ggctagtaga aacagtgtta tgttgggaag cagggtaccc     1560

ccaaagatgt tccctgtagg tcacggcact cccaaaagca cacaagcaca tacagacata     1620

tgcatcccca cacacgccta tgcacaaacg tggattatcg cacagactgg gaggtttagt     1680

ggtgcatttc tcctctgttt tctttttaat atacatttaa aatacagtat tatcacttta     1740

taaaacatac attaagccta ataaatggac caataagcca aactatcagt attttgtata     1800

tcctgcataa actctaattt agttcctcaa catattttca gtgtttatgc agacctttag     1860

agttaagcct ttgtatttcc atgttattcc acaatatgca atatttctct gagtagcttc     1920

tgctatgata ttcttatgaa gaaaaggggc aactttctgt ccactatagg agagaattca     1980

gccgaagata tgagagtaat gagagacatt ttccagtcat tggatcgtgt tttcttttgt     2040

ccattattgt actgtgctgt accacattta tttctatatt cattttgtaa aaaatttaaa     2100

agtgctattt tgtttgtatt tgaaaatctc tgtgaataaa ttctctcttt gatcaataaa     2160

aaaaaaaaaa aaaaaaaaaa                                                 2180


<210>  2040
<211>  3428
<212>  DNA
<213>  homo sapiens

<400>  2040
ccaagatctt cctcctaccc tcccctcttt cccttctccc gcggtcggcc ctcgccccct       60

cccccaggcc cagcgcgggc gctcggcgcg tccagacccg cggcgcgatg ccggcagttt      120

aggatccaaa gcttctctgc tccttttgtt ctttccttcc cttttttaaa aaaagagggg      180

ggaaatccca gtggtgggca gcctggcacg cacacagtcg ccctcatacc ccgacaaaag      240

cagatgcact ttgacttctg acagctctac ctcaagcccc ggagaactca gcggcgcttt      300

cctcgcaacc cgagctcggc gagtcgtcgt cttcttcttc tccgttttta tttatttatt      360

tccgttcccg ccgccgttct cgctgacctt cactcctccg cgggctctga gcagaagggt      420

cgcattctct cccgcctgag acttcttttc ctcgccccgg gagctcaggc ggcgccgctc      480

cagcccgggg ccccgggact ccccggctgc acacttcact gagacgcccc cccaggcccc      540

gatcagcctc gtttcctcca ccctactttg atttcctggt gcgagttttg gcttgcacgg      600

ccgagtgtgt gtcctctttt tggagagact ggggagctcg tgccgattgt cttcaggagt      660

catcccctgg gctctacttt gcccctctct ctctctgggc ctcatcagac caaaccaaag      720

accatggttc actgtgccgg ctgcaaaagg cccatcctgg accgctttct cttgaacgtg      780

ctggacaggg cctggcacgt caagtgcgtc cagtgctgtg aatgtaaatg caacctgacc      840

gagaagtgct tctccaggga aggcaaactc tactgcaaga acgacttctt ccggtgtttc      900

ggtaccaaat gcgcaggctg cgctcagggc atctccccta gcgacctggt gcggagagcg      960

cggagcaaag tgtttcacct gaactgcttc acctgcatga tgtgtaacaa gcagctctcc     1020

actggcgagg aactctacat catcgacgag aataagttcg tctgcaaaga ggattaccta     1080

agtaacagca gtgttgccaa agagaacagc cttcactcgg ccaccacggg cagtgacccc     1140

agtttgtctc cggattccca agacccgtcg caggacgacg ccaaggactc ggagagcgcc     1200

aacgtgtcgg acaaggaagc gggtagcaac gagaatgacg accagaacct gggcgccaag     1260

cggcggggac cgcgcaccac catcaaagcc aagcagctgg agacgctgaa ggccgccttc     1320

gctgctacac ccaagcccac ccgccacatc cgcgagcagc tggcgcagga gaccggcctc     1380

aacatgcgcg tcattcaggt ctggttccag aaccggcgct ccaaggagcg gaggatgaag     1440

cagctgagcg ccctgggcgc ccggcgccac gccttcttcc gcagtccgcg ccggatgcgg     1500

ccgctggtgg accgcctgga gccgggcgag ctcatcccca atggtccctt ctccttctac     1560

ggagattacc agagcgagta ctacgggccc gggggcaact acgacttctt cccgcaaggc     1620

cccccgtcct cgcaggccca gacaccagtg gacctaccct tcgtgccgtc atctgggccg     1680

tccgggacgc ccctgggtgg cctggagcac ccgctgccgg gccaccaccc gtcgagcgag     1740

gcgcagcggt ttaccgacat cctggcgcac ccacccgggg actcgcccag ccccgagccc     1800

agcctgcccg ggcctctgca ctccatgtcg gccgaggtct tcggacccag cccgcccttc     1860

tcgtcgctgt cggtcaacgg tggggcgagc tacggaaacc acctgtccca cccccccgaa     1920

atgaacgagg cggccgtgtg gtagcggggt ctcgcacggt ctgcggagtt cgtggttgta     1980

cagaaatgaa cctttattta agaaaaatag aaaaaaaaaa acataaaaag caagtcccca     2040

cccccttcct ccagcctcga gaaccattct ccttctgggg agaccggatg gaaaaggggg     2100

acacgaaata ggatccaaat cggcctcgag gtgggactgg gatccgcgca ctggctgtcg     2160

acgtgcagaa ctggggctcc ccaaaggaaa cgcagacctc tccccaactc ccacctggac     2220

ccggatccgt agacagaccc cgcgggcgtg tgcgcctggc aggcgggcgg cgaaaagacg     2280

tccagggcag ccgcgggtgc gcacagccgt tggcgatgcc aggagccgtg gggagggagg     2340

ccgtgagcac agccgggtga aggaagtgaa gcggcccagg gcgctcccgg gccagccagg     2400

agggttctag ctctgggata tcccttatta gtgttgtctc agagttcaac aacagcgaca     2460

aaaaactctt atagcttcag aaacgccgac ctgccgtgca tcaggtggga ctatatatat     2520

attttttgtc tatctggatt tttggttttt gtttttgcca aaattgcaaa attctaaatg     2580

taaagccctc cgtatcaact cttctacctt cgcaaaacta cacatacaca catacacacg     2640

tacacggaca cactcggtaa gatggtctcc agccagaccg ctcagtaaaa tgacttgaac     2700

atcagctgta caagaaaagt attctacctt cacacacaaa aagttaaaaa aaaaaaaaaa     2760

gactattgaa ctaaaaacag tcaactgttt acgtataatg ttaaattcag gagttcagtg     2820

ttttactaat atatcctgtt ttgaaacctc ttgttcgaaa acaaaatgtt ttgagcaatc     2880

aaccaaaatt gttccttttc ttttcctgta gatgttctga cagatttgca gggctttcgg     2940

ctcactgtgc tagtatgtaa aaaggtgttg tttacacgag gcaaagagaa aacatgctat     3000

tcagacagtt gccaaataga ataattatag cacaaatact gtaaaggtgc ctggcaccag     3060

caacctgaga aagtgttaaa aaaaaaaaaa aaaaagtgtt acaagattta aaaaaaaaca     3120

tctttgctaa tttttttgtc ctgttgaaca ttcatggaat tgttaatatg acttatatag     3180

acccacacag gttttatttt tgtgtcttta aaataaaagt ccaaaatatt taaattttat     3240

ggtcaaatat gcagtcaaca gctgctactt tttctttata tattaaattt ctcatatgtc     3300

ttttattgtt ctaataaacc taagcttgtg tgacctccag tgcatattag accattcact     3360

gtatgaaaga aaacatgttg aataaatttg tgagttttta ataaaaatag aaaatctgat     3420

gtttagat                                                              3428


<210>  2041
<211>  3676
<212>  DNA
<213>  homo sapiens

<400>  2041
gagagacgag ggcagcggag gaggcgagga gcgccgggta ccgggccggg ggagccgcgg       60

gctctcgggg aagagacgga tgatgaacaa gctttacatc gggaacctga gccccgccgt      120

caccgccgac gacctccggc agctctttgg ggacaggaag ctgcccctgg cgggacaggt      180

cctgctgaag tccggctacg ccttcgtgga ctaccccgac cagaactggg ccatccgcgc      240

catcgagacc ctctcgggta aagtggaatt gcatgggaaa atcatggaag ttgattactc      300

agtctctaaa aagctaagga gcaggaaaat tcagattcga aacatccctc ctcacctgca      360

gtgggaggtg ttggatggac ttttggctca atatgggaca gtggagaatg tggaacaagt      420

caacacagac acagaaaccg ccgttgtcaa cgtcacatat gcaacaagag aagaagcaaa      480

aatagccatg gagaagctaa gcgggcatca gtttgagaac tactccttca agatttccta      540

catcccggat gaagaggtga gctccccttc gccccctcag cgagcccagc gtggggacca      600

ctcttcccgg gagcaaggcc acgcccctgg gggcacttct caggccagac agattgattt      660

cccgctgcgg atcctggtcc ccacccagtt tgttggtgcc atcatcggaa aggagggctt      720

gaccataaag aacatcacta agcagaccca gtcccgggta gatatccata gaaaagagaa      780

ctctggagct gcagagaagc ctgtcaccat ccatgccacc ccagagggga cttctgaagc      840

atgccgcatg attcttgaaa tcatgcagaa agaggcagat gagaccaaac tagccgaaga      900

gattcctctg aaaatcttgg cacacaatgg cttggttgga agactgattg gaaaagaagg      960

cagaaatttg aagaaaattg aacatgaaac agggaccaag ataacaatct catctttgca     1020

ggatttgagc atatacaacc cggaaagaac catcactgtg aagggcacag ttgaggcctg     1080

tgccagtgct gagatagaga ttatgaagaa gctgcgtgag gcctttgaaa atgatatgct     1140

ggctgttaac caacaagcca atctgatccc agggttgaac ctcagcgcac ttggcatctt     1200

ttcaacagga ctgtccgtgc tatctccacc agcagggccc cgcggagctc cccccgctgc     1260

cccctaccac cccttcacta cccactccgg atacttctcc agcctgtacc cccatcacca     1320

gtttggcccg ttcccgcatc atcactctta tccagagcag gagattgtga atctcttcat     1380

cccaacccag gctgtgggcg ccatcatcgg gaagaagggg gcacacatca aacagctggc     1440

gagattcgcc ggagcctcta tcaagattgc ccctgcggaa ggcccagacg tcagcgaaag     1500

gatggtcatc atcaccgggc caccggaagc ccagttcaag gcccagggac ggatctttgg     1560

gaaactgaaa gaggaaaact tctttaaccc caaagaagaa gtgaagctgg aagcgcatat     1620

cagagtgccc tcttccacag ctggccgggt gattggcaaa ggtggcaaga ccgtgaacga     1680

actgcagaac ttaaccagtg cagaagtcat cgtgcctcgt gaccaaacgc cagatgaaaa     1740

tgaggaagtg atcgtcagaa ttatcgggca cttctttgct agccagactg cacagcgcaa     1800

gatcagggaa attgtacaac aggtgaagca gcaggagcag aaataccctc agggagtcgc     1860

ctcacagcgc agcaagtgag gctcccacag gcaccagcaa aacaacggat gaatgtagcc     1920

cttccaacac ctgacagaat gagaccaaac gcagccagcc agatcgggag caaaccaaag     1980

accatctgag gaatgagaag tctgcggagg cggccaggga ctctgccgag gccctgagaa     2040

ccccaggggc cgaggagggg cggggaaggt cagccaggtt tgccagaacc accgagcccc     2100

gcctcccgcc ccccagggct tctgcaggct tcagccatcc acttcaccat ccactcggat     2160

ctctcctgaa ctcccacgac gctatccctt ttagttgaac taacataggt gaacgtgttc     2220

aaagccaagc aaaatgcaca ccctttttct gtggcaaatc gtctctgtac atgtgtgtac     2280

atattagaaa gggaagatgt taagatatgt ggcctgtggg ttacacaggg tgcctgcagc     2340

ggtaatatat tttagaaata atatatcaaa taactcaact aactccaatt tttaatcaat     2400

tattaatttt tttttctttt taaagagaaa gcaggctttt ctagacttta aagaataaag     2460

tctttgggag gtctcacggt gtagagagga gctttgaggc cacccgcaca aaattcaccc     2520

agagggaaat ctcgtcggaa ggacactcac ggcagttctg gatcacctgt gtatgtcaac     2580

agaagggata ccgtctcctt gaagaggaaa ctctgtcact cctcatgcct gtctagctca     2640

tacacccatt tctctttgct tcacaggttt taaactggtt ttttgcatac tgctatataa     2700

ttctctgtct ctctctgttt atctctcccc tccctcccct ccccttcttc tccatctcca     2760

ttcttttgaa tttcctcatc cctccatctc aatcccgtat ctacgcaccc cccccccccc     2820

aggcaaagca gtgctctgag tatcacatca cacaaaagga acaaaagcga aacacacaaa     2880

ccagcctcaa cttacacttg gttactcaaa agaacaagag tcaatggtac ttgtcctagc     2940

gttttggaag aggaaaacag gaacccacca aaccaaccaa tcaaccaaac aaagaaaaaa     3000

ttccacaatg aaagaatgta ttttgtcttt ttgcattttg gtgtataagc catcaatatt     3060

cagcaaaatg attcctttct ttaaaaaaaa aaaatgtgga ggaaagtaga aatttaccaa     3120

ggttgttggc ccagggcgtt aaattcacag atttttttaa cgagaaaaac acacagaaga     3180

agctacctca ggtgttttta cctcagcacc ttgctcttgt gtttccctta gagattttgt     3240

aaagctgata gttggagcat ttttttattt ttttaataaa aatgagttgg aaaaaaaata     3300

agatatcaac tgccagcctg gagaaggtga cagtccaagt gtgcaacagc tgttctgaat     3360

tgtcttccgc tagccaagaa cctatatggc cttcttttgg acaaaccttg aaaatgttta     3420

tttaaaaaaa aaaaagatga caaagaaaaa cagagagaga gaatattgga gatgtcctga     3480

attttaatag ggtacgcgcc attagggctt tttgcgctaa aggatgaaca tgtactggtt     3540

tatgtggaca agccattata ccaccagact gcaatgccag tttcctctac tgcaaacagt     3600

gttctgtgac aaaaaaaaaa aaaaaaaaaa gaaaaaaaaa gaaaaaacag aaatatatcc     3660

agctaacaag aaaaaa                                                     3676


<210>  2042
<211>  3676
<212>  DNA
<213>  homo sapiens

<400>  2042
gagagacgag ggcagcggag gaggcgagga gcgccgggta ccgggccggg ggagccgcgg       60

gctctcgggg aagagacgga tgatgaacaa gctttacatc gggaacctga gccccgccgt      120

caccgccgac gacctccggc agctctttgg ggacaggaag ctgcccctgg cgggacaggt      180

cctgctgaag tccggctacg ccttcgtgga ctaccccgac cagaactggg ccatccgcgc      240

catcgagacc ctctcgggta aagtggaatt gcatgggaaa atcatggaag ttgattactc      300

agtctctaaa aagctaagga gcaggaaaat tcagattcga aacatccctc ctcacctgca      360

gtgggaggtg ttggatggac ttttggctca atatgggaca gtggagaatg tggaacaagt      420

caacacagac acagaaaccg ccgttgtcaa cgtcacatat gcaacaagag aagaagcaaa      480

aatagccatg gagaagctaa gcgggcatca gtttgagaac tactccttca agatttccta      540

catcccggat gaagaggtga gctccccttc gccccctcag cgagcccagc gtggggacca      600

ctcttcccgg gagcaaggcc acgcccctgg gggcacttct caggccagac agattgattt      660

cccgctgcgg atcctggtcc ccacccagtt tgttggtgcc atcatcggaa aggagggctt      720

gaccataaag aacatcacta agcagaccca gtcccgggta gatatccata gaaaagagaa      780

ctctggagct gcagagaagc ctgtcaccat ccatgccacc ccagagggga cttctgaagc      840

atgccgcatg attcttgaaa tcatgcagaa agaggcagat gagaccaaac tagccgaaga      900

gattcctctg aaaatcttgg cacacaatgg cttggttgga agactgattg gaaaagaagg      960

cagaaatttg aagaaaattg aacatgaaac agggaccaag ataacaatct catctttgca     1020

ggatttgagc atatacaacc cggaaagaac catcactgtg aagggcacag ttgaggcctg     1080

tgccagtgct gagatagaga ttatgaagaa gctgcgtgag gcctttgaaa atgatatgct     1140

ggctgttaac caacaagcca atctgatccc agggttgaac ctcagcgcac ttggcatctt     1200

ttcaacagga ctgtccgtgc tatctccacc agcagggccc cgcggagctc cccccgctgc     1260

cccctaccac cccttcacta cccactccgg atacttctcc agcctgtacc cccatcacca     1320

gtttggcccg ttcccgcatc atcactctta tccagagcag gagattgtga atctcttcat     1380

cccaacccag gctgtgggcg ccatcatcgg gaagaagggg gcacacatca aacagctggc     1440

gagattcgcc ggagcctcta tcaagattgc ccctgcggaa ggcccagacg tcagcgaaag     1500

gatggtcatc atcaccgggc caccggaagc ccagttcaag gcccagggac ggatctttgg     1560

gaaactgaaa gaggaaaact tctttaaccc caaagaagaa gtgaagctgg aagcgcatat     1620

cagagtgccc tcttccacag ctggccgggt gattggcaaa ggtggcaaga ccgtgaacga     1680

actgcagaac ttaaccagtg cagaagtcat cgtgcctcgt gaccaaacgc cagatgaaaa     1740

tgaggaagtg atcgtcagaa ttatcgggca cttctttgct agccagactg cacagcgcaa     1800

gatcagggaa attgtacaac aggtgaagca gcaggagcag aaataccctc agggagtcgc     1860

ctcacagcgc agcaagtgag gctcccacag gcaccagcaa aacaacggat gaatgtagcc     1920

cttccaacac ctgacagaat gagaccaaac gcagccagcc agatcgggag caaaccaaag     1980

accatctgag gaatgagaag tctgcggagg cggccaggga ctctgccgag gccctgagaa     2040

ccccaggggc cgaggagggg cggggaaggt cagccaggtt tgccagaacc accgagcccc     2100

gcctcccgcc ccccagggct tctgcaggct tcagccatcc acttcaccat ccactcggat     2160

ctctcctgaa ctcccacgac gctatccctt ttagttgaac taacataggt gaacgtgttc     2220

aaagccaagc aaaatgcaca ccctttttct gtggcaaatc gtctctgtac atgtgtgtac     2280

atattagaaa gggaagatgt taagatatgt ggcctgtggg ttacacaggg tgcctgcagc     2340

ggtaatatat tttagaaata atatatcaaa taactcaact aactccaatt tttaatcaat     2400

tattaatttt tttttctttt taaagagaaa gcaggctttt ctagacttta aagaataaag     2460

tctttgggag gtctcacggt gtagagagga gctttgaggc cacccgcaca aaattcaccc     2520

agagggaaat ctcgtcggaa ggacactcac ggcagttctg gatcacctgt gtatgtcaac     2580

agaagggata ccgtctcctt gaagaggaaa ctctgtcact cctcatgcct gtctagctca     2640

tacacccatt tctctttgct tcacaggttt taaactggtt ttttgcatac tgctatataa     2700

ttctctgtct ctctctgttt atctctcccc tccctcccct ccccttcttc tccatctcca     2760

ttcttttgaa tttcctcatc cctccatctc aatcccgtat ctacgcaccc cccccccccc     2820

aggcaaagca gtgctctgag tatcacatca cacaaaagga acaaaagcga aacacacaaa     2880

ccagcctcaa cttacacttg gttactcaaa agaacaagag tcaatggtac ttgtcctagc     2940

gttttggaag aggaaaacag gaacccacca aaccaaccaa tcaaccaaac aaagaaaaaa     3000

ttccacaatg aaagaatgta ttttgtcttt ttgcattttg gtgtataagc catcaatatt     3060

cagcaaaatg attcctttct ttaaaaaaaa aaaatgtgga ggaaagtaga aatttaccaa     3120

ggttgttggc ccagggcgtt aaattcacag atttttttaa cgagaaaaac acacagaaga     3180

agctacctca ggtgttttta cctcagcacc ttgctcttgt gtttccctta gagattttgt     3240

aaagctgata gttggagcat ttttttattt ttttaataaa aatgagttgg aaaaaaaata     3300

agatatcaac tgccagcctg gagaaggtga cagtccaagt gtgcaacagc tgttctgaat     3360

tgtcttccgc tagccaagaa cctatatggc cttcttttgg acaaaccttg aaaatgttta     3420

tttaaaaaaa aaaaagatga caaagaaaaa cagagagaga gaatattgga gatgtcctga     3480

attttaatag ggtacgcgcc attagggctt tttgcgctaa aggatgaaca tgtactggtt     3540

tatgtggaca agccattata ccaccagact gcaatgccag tttcctctac tgcaaacagt     3600

gttctgtgac aaaaaaaaaa aaaaaaaaaa gaaaaaaaaa gaaaaaacag aaatatatcc     3660

agctaacaag aaaaaa                                                     3676


<210>  2043
<211>  2459
<212>  DNA
<213>  homo sapiens

<400>  2043
gggagcgccg gggaggcggg cggaggcggg cggaggcggg gggcggggag cccgaggggt       60

ggaagccggc ggcggccgag cggggtcagt tctctgtagt gtttgccaat gttggagccg      120

tctgcaaagt gtccccggca agaaggtatc attgcccagt gcctaagatc ttttatgttc      180

agctcactgt aggaaataat gaattttttg gggaaggaaa gactcgacaa gctgctagac      240

acaatgctgc aatgaaagcc ctccaagcac tgcagaatga acctattcca gaaagatctc      300

ctcagaatgg tgaatcagga aaggatgtgg atgatgacaa agatgcaaat aagtctgaga      360

tcagcttagt gtttgaaatt gctctgaagc gaaatatgcc tgtcagtttt gaggttatta      420

aagaaagtgg accaccacat atgaaaagct ttgttactcg agtgtcagta ggagagttct      480

ctgcagaagg agaaggaaat agcaaaaaac tctccaagaa gcgcgctgcg accaccgtct      540

tacaggagct taaaaaactt ccacctcttc ctgtggtgga aaagccaaaa ctatttttta      600

aaaaacgccc taaaacaata gtaaaggccg gaccagaata tggccaaggg atgaacccta      660

ttagccgcct ggcgcaaatt caacaggcca aaaaggaaaa ggagccggat tatgttttgc      720

tttcagaaag aggaatgcct cgacgtcgag aatttgtgat gcaggtgaag gtaggcaatg      780

aagttgctac aggaacagga cctaataaaa agatagccaa aaaaaatgct gcagaagcaa      840

tgctgttaca acttggttat aaagcatcca ctaatcttca ggatcaactt gagaagacag      900

gggaaaacaa aggatggagt ggtccaaagc ctgggtttcc tgaaccaaca aataatactc      960

caaaaggaat tcttcatttg tctcctgatg tttatcaaga gatggaagcc agccgccaca     1020

aagtaatctc tggcactact ctaggctatt tgtcacccaa agatatgaac caaccttcaa     1080

gctctttctt cagtatatct cccacatcga atagttcagc tacaattgcc agggaactcc     1140

ttatgaatgg aacatcttct acagctgaag ccataggttt aaaaggaagt tctcctactc     1200

ccccttgttc tccagtacaa ccttcaaaac aactggaata tttagcaagg attcaaggct     1260

ttcaggcagc cttaagtgcc ttgaaacaat tttctgaaca aggactggat ccaatcgatg     1320

gagcaatgaa tatcgaaaaa ggttctcttg aaaaacaagc caagcatctg agagagaaag     1380

cggacaataa ccaggcaccc ccgggctcca tcgctcagga ctgcaagaaa tcaaactcgg     1440

ccgtctagca gctcccagaa cccgcggctg ccaccgcatc cttataaacc tgtcagcacg     1500

catgagggtg tctgtgttca gggaaatgaa tgactaatac cattatttga gtcttatgtg     1560

aagacaacac tattctaaca cgagagataa tatacatggt actgtttatt caactgggga     1620

aaaataaaac tttgagcatt tcccttggaa ctcgagatca gatcataact catttgccta     1680

gaggcagcag aaatctgatc ctgctactgg agcttaaaat aacaagtaaa gaaaagtgtt     1740

agaaacaaag ctaaaatttt aacatgatta ataatagaga agttgggttt ggttctgttg     1800

ttatgattgt tttgtcgtgg tgcttgtgtt cagttatatt ctctctctct ctcatttcaa     1860

atactgcttg acaattcgaa aatgaaccaa tgatgtgctg tggaatgtga tggttgtctt     1920

catatagagt cacatggttt ctctttttat gcagatattt ataatcttca tcctatatca     1980

gtaggaataa ctataaggtg cactacaaaa agatgtatgc aaacaaacat gttttaaatc     2040

aggtcagata tctgatgaaa aatacgaact aatgttaaga gcaagtagtt tcaacatact     2100

ccaggaactg agaaacaaaa caaagcaatt gtgggttttg agctccatat actcttagca     2160

agtaaggggg cgtcttgccc ctatatatca tcttcccgga ttccactccc tgttgtggga     2220

atcgcgccca cccccatccg tgtgttgtag ccactcacgg tttgcatcaa gagtgttttt     2280

tgtaactgcc tctggacttg ggacagtgag taggatcaaa aataaataat gtacatgacg     2340

gggaagggaa aaacctgttg gagttgcttc cagccagcca cgctccgggc cagcatgttg     2400

gaatccagcg tggagcagat gcagtaaaaa tgtggttggt ttctgtgtga aaaaaaaaa      2459


<210>  2044
<211>  2068
<212>  DNA
<213>  homo sapiens

<400>  2044
ggagggtttt gctctttgtg tgggtgtgtg agtggctatg atcctagttg tccagctgct       60

gcgtggagaa taagtaaagc aggtctgaat gacaccaggt cgctgctgtc ttgcggctga      120

cattcaggta gagacgttca tcttcactga cggggaagat gaggccctgg ccaggcacac      180

gggcaacgtg gtcatcacaa actgctcggc cgcccacagc cgccaggcgc tgtcctgcaa      240

gatggccgtg gagtatgacc gcttcatcga gtccggcagg aagtggttct gccacgtgga      300

cgatgacaac tacgtcaacc tgcgggccct gctgcggctg ctggccagct acccgcacac      360

gcgggacgtc tacgtcggca agcccagcct ggacaggccc atccaggcca tggagcgggt      420

cagcgagaac aaggtgcgtc ctgtccactt ctggtttgcc acgggcggcg ctggcttctg      480

catcagccgt gggctggctc tgaagatgag cccgtgggcc agcgggggtc acttcatgaa      540

tacggctgag cggatccggc tgcctgatga ctgcaccatc ggctacatcg tggaggccct      600

gctgggtgtg cccctcatcc gcagcggcct cttccactcc cacctggaga acctgcagca      660

ggtgcccacc tcggagctcc acgagcaggt gacgctgagc tacggtatgt ttgaaaacaa      720

gcggaacgcc gtccacgtga aggggccctt ctcggtggag gccgacccat ccaggttccg      780

ctccatccac tgccacctgt acccggacac accctggtgt ccccgcactg ccatcttcta      840

gtggccatgg ctgagaccca atccctgggc gcccctggta tccaaagggc ccagggaccc      900

tgttgcgctg ccctggcctc ggcattcgag gctcccctag ggccgtgcct gtgcgtgtgc      960

gtgtgcgtgt gtgtgtgtgt gtactgcatg cccacccggg tagcaggctg ctgggcagtt     1020

ctgctctgtg gaggggcggg caccagcgcc acttatgtgc ctctgctccg agggccagtg     1080

ggctgcaggg cctgcttgga ggaaggattt gtgtgtcgga ggccactccg agggcaattc     1140

tgttaggatt tttggatctt tctacagcta cggggctccg ggctactttg cagggatgcg     1200

atgcgtaggt gcctttctct tcctgctgac cacaagctct gtgctggggg tacctgtgcc     1260

ctgaagtcct ggcccctgtg tcatagcccc aagtacgact cactgagcca tgctcattgc     1320

aggggaggct gggtctgggg gtgcgtgacc caatcccctt cctcctggcc tggacgctgt     1380

ggcttaagag taacagcagc caccgcccag ttccagtggc cccacgaagc ccccagtggc     1440

tggctgtcca gctgggcaaa cagtggcacc cctcccagct cttctgagtg gggagtcttc     1500

caggcctcct cagaggtctt ccctttgcct ccccaggaca gggtgagtca gagctcagca     1560

tttaatctcc tctccaaagt agagagcaag tcgcccacag tgggcgtgtc tgtaaatatt     1620

gtgacagtat ttttttactg tgctgttttt tttgaaaggg gatgggtaaa aagtagggtg     1680

ttcttgtttt ttgcttggga gggtgggggt gggggagggt cttattttat cttatctttt     1740

ctgtggatca gaaaaaacag aagccaaact cggggtcatc tttgttttta aagctgaagt     1800

gggactgtct ggcactctgt gtatttatgc gttccagcat ctggaacctc ccatccctgc     1860

cctcctcctg tgtagctgcc acctccccgc tgggcccagc atggctcacc tgtcccgtgg     1920

gctgtgtttc ttgttgtttt tctctttgca aagacatagc taggaaagcg aatgataagg     1980

gaaaagttct cagggaattg aagtgttgtt gctatggtga cgtccttttg ctgtgaataa     2040

aggtgctctt tgcagcaaaa aaaaaaaa                                        2068


<210>  2045
<211>  3096
<212>  DNA
<213>  homo sapiens

<400>  2045
attctttctt cgtgttcctg tgcgggattg gtgtgcccag gggtttggct ttccaattgg       60

ctaacgccgg ggtgggtggg gaatgtgggg agatttgaat ttgaaaccgg tagggagtga      120

taatccgcat tcagttgtcg aggagtgcca gtcaccttca gtttctggag ctggccgtca      180

acatgtcctt tcctaaggcg cccttgaaac gattcaatga cccttctggt tgtgcaccat      240

ctccaggtgc ttatgatgtt aaaactttag aagtattgaa aggaccagta tcctttcaga      300

aatcacaaag atttaaacaa caaaaagaat ctaaacaaaa tcttaatgtt gacaaagata      360

ctaccttgcc tgcttcagct agaaaagtta agtcttcgga atcaaagatt cgtgttcttc      420

tacaggaacg tggtgcccag gacaggcgga tccaggatct ggaaactgag ttggaaaaga      480

tggaagcaag gctaaatgct gcactaaggg aaaaaacatc tctctctgca aataatgcta      540

cactggaaaa acaacttatt gaattgacca ggactaatga actactaaaa tctaagtttt      600

ctgaaaatgg taaccagaag aatttgagaa ttctaagctt ggagttgatg aaacttagaa      660

acaaaagaga aacaaagatg aggggtatga tggctaagca agaaggcatg gagatgaagc      720

tgcaggtcac ccaaaggagt ctcgaagagt ctcaagggaa aatagcccaa ctggagggaa      780

aacttgtttc aatagagaaa gaaaagattg atgaaaaatc tgaaacagaa aaactcttgg      840

aatacatcga agaaattagt tgtgcttcag atcaagtgga aaaatacaag ctagatattg      900

cccagttaga agaaaatttg aaagagaaga atgatgaaat tttaagcctt aagcagtctc      960

ttgaggagaa tattgttata ttatctaaac aagtagaaga tctaaatgtg aaatgtcagc     1020

tgcttgaaaa agaaaaagaa gaccatgtca acaggaatag agaacacaac gaaaatctaa     1080

atgcagagat gcaaaactta aaacagaagt ttattcttga acaacaggaa cgtgaaaagc     1140

ttcaacaaaa agaattacaa attgattcac ttctgcaaca agagaaagaa ttatcttcga     1200

gtcttcatca gaagctctgt tcttttcaag aggaaatggt taaagagaag aatctgtttg     1260

aggaagaatt aaagcaaaca ctggatgagc ttgataaatt acagcaaaag gaggaacaag     1320

ctgaaaggct ggtcaagcaa ttggaagagg aagcaaaatc tagagctgaa gaattaaaac     1380

tcctagaaga aaagctgaaa gggaaggagg ctgaactgga gaaaagtagt gctgctcata     1440

cccaggccac cctgcttttg caggaaaagt atgacagtat ggtgcaaagc cttgaagatg     1500

ttactgctca atttgaaagc tataaagcgt taacagccag tgagatagaa gatcttaagc     1560

tggagaactc atcattacag gaaaaagcgg ccaaggctgg gaaaaatgca gaggatgttc     1620

agcatcagat tttggcaact gagagctcaa atcaagaata tgtaaggatg cttctagatc     1680

tgcagaccaa gtcagcacta aaggaaacag aaattaaaga aatcacagtt tcttttcttc     1740

aaaaaataac tgatttgcag aaccaactca agcaacagga ggaagacttt agaaaacagc     1800

tggaagatga agaaggaaga aaagctgaaa aagaaaatac aacagcagaa ttaactgaag     1860

aaattaacaa gtggcgtctc ctctatgaag aactatataa taaaacaaaa ccttttcagc     1920

tacaactaga tgcttttgaa gtagaaaaac aggcattgtt gaatgaacat ggtgcagctc     1980

aggaacagct aaataaaata agagattcat atgctaaatt attgggtcat cagaatttga     2040

aacaaaaaat caagcatgtt gtgaagttga aagatgaaaa tagccaactc aaatcggaag     2100

tatcaaaact ccgctgtcag cttgctaaaa aaaaacaaag tgagacaaaa cttcaagagg     2160

aattgaataa agttctaggt atcaaacact ttgatccttc aaaggctttt catcatgaaa     2220

gtaaagaaaa ttttgccctg aagaccccat taaaagaagg caatacaaac tgttaccgag     2280

ctcctatgga gtgtcaagaa tcatggaagt aaacatctga gaaacctgtt gaagattatt     2340

tcattcgtct tgttgttatt gatgttgctg ttattatatt tgacatgggt attttataat     2400

gttgtattta attttaactg ccaatcctta aatatgtgaa aggaacattt tttaccaaag     2460

tgtcttttga cattttattt tttcttgcaa atacctcctc cctaatgctc acctttatca     2520

cctcattctg aaccctttcg ctggctttcc agcttagaat gcatctcatc aacttaaaag     2580

tcagtatcat attattatcc tcctgttctg aaaccttagt ttcaagagtc taaaccccag     2640

attcttcagc ttgatcctgg aggtcttttc tagtctgagc ttctttagct aggctaaaac     2700

accttggctt gttattgcct ctactttgat tctgataatg ctcacttggt cctacctatt     2760

atccttctac ttgtccagtt caaataagaa ataaggacaa gcctaacttc atagaaacct     2820

ctctattttt aatcagttgt ttaataattt acaggttctt aggctccatc ctgtttgtat     2880

gaaattataa tctgtggatt ggcctttaag cctgcattct taacaaactc ttcagttaat     2940

tcttagatac actaaaaatc tgagaaactc tacatgtaac tatttcttca gagtttgtca     3000

tatactgctt gtcatctgca tgtctactca gcatttgatt aacatttgtg taatatgaaa     3060

taaaattaca cagtaagtca tttaaccaat taaaaa                               3096


<210>  2046
<211>  3141
<212>  DNA
<213>  homo sapiens

<400>  2046
attctttctt cgtgttcctg tgcgggattg gtgtgcccag gggtttggct ttccaattgg       60

ctaacgccgg ggtgggtggg gaatgtgggg agatttgaat ttgaaaccgg tagggagtga      120

taatccgcat tcagttgtcg aggagtgcca gtcaccttca gtttctggag ctggccgtca      180

acatgtcctt tcctaaggcg cccttgaaac gattcaatga cccttctggt tgtgcaccat      240

ctccaggtgc ttatgatgtt aaaactttag aagtattgaa aggaccagta tcctttcaga      300

aatcacaaag atttaaacaa caaaaagaat ctaaacaaaa tcttaatgtt gacaaagata      360

ctaccttgcc tgcttcagct agaaaagtta agtcttcgga atcaaaggaa tctcaaaaga      420

atgataaaga tttgaagata ttagagaaag agattcgtgt tcttctacag gaacgtggtg      480

cccaggacag gcggatccag gatctggaaa ctgagttgga aaagatggaa gcaaggctaa      540

atgctgcact aagggaaaaa acatctctct ctgcaaataa tgctacactg gaaaaacaac      600

ttattgaatt gaccaggact aatgaactac taaaatctaa gttttctgaa aatggtaacc      660

agaagaattt gagaattcta agcttggagt tgatgaaact tagaaacaaa agagaaacaa      720

agatgagggg tatgatggct aagcaagaag gcatggagat gaagctgcag gtcacccaaa      780

ggagtctcga agagtctcaa gggaaaatag cccaactgga gggaaaactt gtttcaatag      840

agaaagaaaa gattgatgaa aaatctgaaa cagaaaaact cttggaatac atcgaagaaa      900

ttagttgtgc ttcagatcaa gtggaaaaat acaagctaga tattgcccag ttagaagaaa      960

atttgaaaga gaagaatgat gaaattttaa gccttaagca gtctcttgag gagaatattg     1020

ttatattatc taaacaagta gaagatctaa atgtgaaatg tcagctgctt gaaaaagaaa     1080

aagaagacca tgtcaacagg aatagagaac acaacgaaaa tctaaatgca gagatgcaaa     1140

acttaaaaca gaagtttatt cttgaacaac aggaacgtga aaagcttcaa caaaaagaat     1200

tacaaattga ttcacttctg caacaagaga aagaattatc ttcgagtctt catcagaagc     1260

tctgttcttt tcaagaggaa atggttaaag agaagaatct gtttgaggaa gaattaaagc     1320

aaacactgga tgagcttgat aaattacagc aaaaggagga acaagctgaa aggctggtca     1380

agcaattgga agaggaagca aaatctagag ctgaagaatt aaaactccta gaagaaaagc     1440

tgaaagggaa ggaggctgaa ctggagaaaa gtagtgctgc tcatacccag gccaccctgc     1500

ttttgcagga aaagtatgac agtatggtgc aaagccttga agatgttact gctcaatttg     1560

aaagctataa agcgttaaca gccagtgaga tagaagatct taagctggag aactcatcat     1620

tacaggaaaa agcggccaag gctgggaaaa atgcagagga tgttcagcat cagattttgg     1680

caactgagag ctcaaatcaa gaatatgtaa ggatgcttct agatctgcag accaagtcag     1740

cactaaagga aacagaaatt aaagaaatca cagtttcttt tcttcaaaaa ataactgatt     1800

tgcagaacca actcaagcaa caggaggaag actttagaaa acagctggaa gatgaagaag     1860

gaagaaaagc tgaaaaagaa aatacaacag cagaattaac tgaagaaatt aacaagtggc     1920

gtctcctcta tgaagaacta tataataaaa caaaaccttt tcagctacaa ctagatgctt     1980

ttgaagtaga aaaacaggca ttgttgaatg aacatggtgc agctcaggaa cagctaaata     2040

aaataagaga ttcatatgct aaattattgg gtcatcagaa tttgaaacaa aaaatcaagc     2100

atgttgtgaa gttgaaagat gaaaatagcc aactcaaatc ggaagtatca aaactccgct     2160

gtcagcttgc taaaaaaaaa caaagtgaga caaaacttca agaggaattg aataaagttc     2220

taggtatcaa acactttgat ccttcaaagg cttttcatca tgaaagtaaa gaaaattttg     2280

ccctgaagac cccattaaaa gaaggcaata caaactgtta ccgagctcct atggagtgtc     2340

aagaatcatg gaagtaaaca tctgagaaac ctgttgaaga ttatttcatt cgtcttgttg     2400

ttattgatgt tgctgttatt atatttgaca tgggtatttt ataatgttgt atttaatttt     2460

aactgccaat ccttaaatat gtgaaaggaa cattttttac caaagtgtct tttgacattt     2520

tattttttct tgcaaatacc tcctccctaa tgctcacctt tatcacctca ttctgaaccc     2580

tttcgctggc tttccagctt agaatgcatc tcatcaactt aaaagtcagt atcatattat     2640

tatcctcctg ttctgaaacc ttagtttcaa gagtctaaac cccagattct tcagcttgat     2700

cctggaggtc ttttctagtc tgagcttctt tagctaggct aaaacacctt ggcttgttat     2760

tgcctctact ttgattctga taatgctcac ttggtcctac ctattatcct tctacttgtc     2820

cagttcaaat aagaaataag gacaagccta acttcataga aacctctcta tttttaatca     2880

gttgtttaat aatttacagg ttcttaggct ccatcctgtt tgtatgaaat tataatctgt     2940

ggattggcct ttaagcctgc attcttaaca aactcttcag ttaattctta gatacactaa     3000

aaatctgaga aactctacat gtaactattt cttcagagtt tgtcatatac tgcttgtcat     3060

ctgcatgtct actcagcatt tgattaacat ttgtgtaata tgaaataaaa ttacacagta     3120

agtcatttaa ccaattaaaa a                                               3141


<210>  2047
<211>  2834
<212>  DNA
<213>  homo sapiens

<400>  2047
gaacgcaagt cccgcttcgc tctcgggggc ggactcagcg gcggaagtgg cgctgccgga       60

agatcttctt ccgctctgag gcgctactga ggccgcggag ccggactgcg gttggggcgg      120

gaagagccgg ggccgtggct gacatggagc agccctgctg ctgaggccgc gccctccccg      180

ccctgaggtg ggggcccacc aggatgagca agctgcccag ggagctgacc cgagacttgg      240

agcgcagcct gcctgccgtg gcctccctgg gctcctcact gtcccacagc cagagcctct      300

cctcgcacct ccttccgccg cctgagaagc gaagggccat ctctgatgtc cgccgcacct      360

tctgtctctt cgtcaccttc gacctgctct tcatctccct gctctggatc atcgaactga      420

ataccaacac aggcatccgt aagaacttgg agcaggagat catccagtac aactttaaaa      480

cttccttctt cgacatcttt gtcctggcct tcttccgctt ctctggactg ctcctaggct      540

atgccgtgct gcggctccgg cactggtggg tgattgcggt cacgacgctg gtgtccagtg      600

cattcctcat tgtcaaggtc atcctctctg agctgctcag caaaggggca tttggctacc      660

tgctccccat cgtctctttt gtcctcgcct ggttggagac ctggttcctt gacttcaaag      720

tcctacccca ggaagctgaa gaggagcgat ggtatcttgc cgcccaggtt gctgttgccc      780

gtggacccct gctgttctcc ggtgctctgt ccgagggaca gttctattca cccccagaat      840

cctttgcagg gtctgacaat gaatcagatg aagaagttgc tgggaagaaa agtttctctg      900

ctcaggagcg ggagtacatc cgccagggga aggaggccac ggcagtggtg gaccagatct      960

tggcccagga agagaactgg aagtttgaga agaataatga atatggggac accgtgtaca     1020

ccattgaagt tccctttcac ggcaagacgt ttatcctgaa gaccttcctg ccctgtcctg     1080

cggagctcgt gtaccaggag gtgatcctgc agcccgagag gatggtgctg tggaacaaga     1140

cagtgactgc ctgccagatc ctgcagcgag tggaagacaa caccctcatc tcctatgacg     1200

tgtctgcagg ggctgcgggc ggcgtggtct ccccaaggga cttcgtgaat gtccggcgca     1260

ttgagcggcg cagggaccga tacttgtcat cagggatcgc cacctcacac agtgccaagc     1320

ccccgacgca caaatatgtc cggggagaga atggccctgg gggcttcatc gtgctcaagt     1380

cggccagtaa cccccgtgtt tgcacctttg tctggattct taatacagat ctcaagggcc     1440

gcctgccccg gtacctcatc caccagagcc tcgcggccac catgtttgaa tttgcctttc     1500

acctgcgaca gcgcatcagc gagctggggg cccgggcgtg actgtgcccc ctcccaccct     1560

gcgggccagg gtcctgtcgc caccacttcc agagccagaa agggtgccag ttgggctcgc     1620

actgcccaca tgggacctgg ccccaggctg tcaccctcca ccgagccacg cagtgcctgg     1680

agttgactga ctgagcaggc tgtggggtgg agcactggac tccggggccc cactggctgg     1740

aggaagtggg gtctggcctg ttgatgttta catggcgccc tgcctcctgg aggaccagat     1800

tgctctgccc caccttgcca gggcagggtc tgggctgggc acctgacttg gctggggagg     1860

accagggccc tgggcagggc agggcagcct gtcacccgtg tgaagatgaa ggggctcttc     1920

atctgcctgc gctctcgtcg gtttttttag gattattgaa agagtctggg acccttgttg     1980

gggagtgggt ggcaggtggg ggtgggctgc tggccatgaa tctctgcctc tcccaggctg     2040

tccccctcct cccagggcct cctgggggac ctttgtatta agccaattaa aaacatgaat     2100

ttaaaaaaaa aaaaaaattc cagcccctcc cactgccttg cctcttgagg gaagagaaag     2160

gcaggcagca gcttggatga agagggaaga cccctcacac agcctctcct gggctcacag     2220

gagggcggag cccggggagc cagttcctga aacatgcccc ccattccccc cccgcccacc     2280

ccccactccc cgctttcctg accagttcaa ctgagcagat gactggtcag aaaaaaatgc     2340

cccgccccct gccaggcttc agcggggcaa gtttaaagtc tctagtccag gaatggaggt     2400

gggggtatgg gcacctggca gtgcccacag caagccttga ctgtgtggcc tggagatggg     2460

gcctgagctt cagggtcact gaggcacctc tgggatccag gccacctgga gccccggacc     2520

tcccagactc cactcaccca ttccctctcc ccgcacggca ctcacaccag gggcggcctg     2580

gagcccggat cgcagggcgg ggccaggcca ctgcctgcct tcctcctccc tcccggctgg     2640

cctgccccct tgcctgcctg catgcaggct tccagcagag ccagcttctt cagagccagg     2700

tggatcctgt ttcggtcctg cctaggtgtg tgaccctggg cgaatctacc tctctcagct     2760

tctgcttccc actttatgaa aatgggactg atgtcacagg gttgttatga gattaaaaga     2820

tatgaagaac cggg                                                       2834


<210>  2048
<211>  6365
<212>  DNA
<213>  homo sapiens

<400>  2048
cctgggcagt ggcggggctg gccgaggctg cggcgtttct ccccaaggaa gtgtcttctc       60

cgctttccct gttcttctgt ttctcacaca ctttctatct cattctgtaa ctttcaagcc      120

tttccttcta actgtatgta tttagttact tgttttcaag ctggttccct ctctggcccc      180

ctggcctggg gaaagcctcc acacttactg cgggtcttgt ttagagtctg agtttgtgag      240

attatttggg ggagagtggg cgagtggctg acaggtgacc cccaggagga ggattcctgg      300

ggctggtgtc ttctcccagc tgctgcttcc agtgggcctg ggcccaggac tggacctccg      360

ctggcacccc tgagtgcctc cctgccaggc catgctgctg tagaccctaa cagcgtctct      420

tcctggccaa gagaagcctg tccccaagaa caggagagcc atggccggcc tccgagggaa      480

cgctgtggct ggcctcctct ggatgctgct gctgtggagt gggggcggcg gctgccaggc      540

tcagcgggca ggttgcaaaa gtgtccacta cgatctggtc ttcctcctgg acacctcctc      600

cagcgtgggc aaggaggact ttgagaaggt ccggcagtgg gtggccaacc tggtggacac      660

cttcgaggtg ggccccgacc gcacccgtgt gggggtcgtg cgctacagcg accggcccac      720

cacggccttc gagttgggac tctttggctc gcaggaggag gtcaaggcgg ctgcccggcg      780

tctcgcctac cacgggggca acaccaacac gggagacgcg ctccgctaca tcacggcccg      840

cagcttctcc ccacacgccg gcggccgccc cagggaccgc gcctacaagc aggtggccat      900

cctgctcacc gacggccgca gccaggacct ggtgctggac gccgcggcgg cagcccaccg      960

cgctggcatc cgcatctttg ccgtgggcgt gggcgaggca ctcaaggagg agctggagga     1020

gatcgcctca gagcccaagt ccgcccacgt cttccacgtg tccgacttca atgccatcga     1080

caagatccgg ggcaagctgc ggcgccgtct ttgtgaaaat gtgctctgtc ctagcgttcg     1140

tgtagaagga gatcgcttta agcacaccaa tggaggaacc aaggaaatca caggttttga     1200

cctgatggat ttgttcagtg tgaaggaaat cttggggaag agagagaatg gagctcagag     1260

ttcctatgta cggatgggat ccttccctgt ggtgcaaagt actgaggatg tgttccccca     1320

aggtttacct gatgagtacg cctttgtcac aaccttccgg ttcaggaaaa cctctcggaa     1380

ggaagactgg tatatctggc aggtcatcga ccagtacagc atcccacagg tctccatccg     1440

gctggatggt gaaaacaagg cagtcgagta caacgctgtg ggtgccatga aagatgctgt     1500

cagggtggtc ttccgaggtt ctcgggtcaa tgacctcttt gaccgggact ggcacaagat     1560

ggccctgagc atccaggccc agaacgtctc cctgcacatt gactgtgcgc tggtgcagac     1620

actacccatc gaggaacggg agaacattga catccagggc aagactgtga ttggcaagcg     1680

cctctacgac agtgtgccca ttgactttga cctacagcgg attgtgatct attgtgactc     1740

gagacacgca gaattggaga cttgttgtga tatcccctcg ggtccgtgcc aggtgaccgt     1800

ggtgacagag cctccacctc cacccccacc ccagcggcct cccaccccag gcagtgaaca     1860

gattgggttt ttgaagacca tcaactgctc ctgcccagct ggagagaagg gtgaaatggg     1920

agttgctggc cccatggggc tccctggtcc aaagggagac ataggagcca ttgggccggt     1980

tggcgctcct ggacctaagg gagagaaagg tgatgtgggc ataggacctt ttggccaagg     2040

ggaaaagggt gaaaagggtt ccctgggcct gcccggcccc cctgggagag acggcagcaa     2100

aggcatgaga ggggagccag gagagctggg agagccgggg ctgccgggtg aggtcggcat     2160

gcgggggccc caaggaccac ctggactccc cggacctcct ggacgtgtcg gagctcctgg     2220

tctccaagga gaacgaggtg aaaagggaac tcgaggagaa aagggagagc gaggcctgga     2280

tggattccct gggaagcctg gggacacagg acagcagggc aggcccggcc cttctggtgt     2340

ggcaggaccc cagggagaaa agggtgacgt gggacctgcg gggccacctg gtgtaccagg     2400

ctcagtggtg cagcaagagg gcttgaaagg ggaacaggga gctccaggac ccagaggtca     2460

ccaaggcgcc cccggtcctc caggagctcg gggtccaata ggcccagaag gcagggatgg     2520

acctcctggt ttgcaaggtc tccgagggaa gaaaggtgac atgggaccac ctggaatccc     2580

tggattgctg gggctgcagg gccctccagg accccctggt gtcccaggcc cccctggacc     2640

gggaggttct ccgggtttgc ctggagagat cggcttcccg ggaaagcctg gacctcctgg     2700

gcccacggga ccccctggaa aggacgggcc aaatggacca ccaggtccgc caggaaccaa     2760

gggagaacca ggagaaagag gggaagatgg tctgcctgga aaaccaggcc ttcggggaga     2820

aattggggag cagggcctgg caggccgacc tggagagaag ggagaagcag gcctcccagg     2880

ggctccaggc ttcccaggtg tgagaggaga gaaaggagac cagggagaaa aaggtgaact     2940

gggacttcca ggactgaaag gtgaccgagg tgaaaagggt gaagctggtc ctgcaggccc     3000

tcccgggtta cctggaacta catccctgtt cacaccacat ccacggatgc ccggagaaca     3060

agggcccaaa ggagagaagg gcgatccagg cctgcctggg gaaccgggac tgcagggccg     3120

tcctggagaa ttggggcctc agggacccac tggaccaccg ggtgccaagg gacaggaagg     3180

tgcacatggg gctcctggag cagctggaaa ccccggtgct cccggacatg tcggtgcccc     3240

cggtcccagt ggccctccag gaagtgtggg tgctcccggc ctcagaggca ccccagggaa     3300

agatggggag cgtggtgaga agggtgcagc gggggaagaa ggcagcccag ggccagttgg     3360

tcccagggga gatcctggtg ctcctgggct ccctgggcca cccggaaaag ggaaggatgg     3420

agagccggga ctccgtggat cacctggact ccctggaccc ctaggaacca aggctgcttg     3480

cggaaaagtc agagggtcag aaaactgtgc actgggaggg caatgtgtta agggggatcg     3540

aggagctcct gggatccctg gttctcctgg cagccgtggt gacccaggca ttggggttgc     3600

tggccctcct ggcccttccg gaccaccagg agacaaagga tccccgggat cacgaggctt     3660

acctggattc cctggccccc agggcccagc cggccgggac ggtgcaccag gaaatccagg     3720

agaaagaggg cctcctggca agccgggcct ctcttcacta ctgtctccag gggacataaa     3780

tctcttggct aaggatgtgt gcaatgactg ccctcctggc cccccaggcc tccctggtct     3840

accaggtttt aaaggggaca aaggtgtccc aggaaagcca gggagagaag gcacagaagg     3900

gaaaaaggga gaggctgggc ctccaggcct accagggccc ccaggaatag ctggaccaca     3960

gggaagtcaa ggagaacgtg gtgcagatgg tgaggttggg cagaaaggtg atcagggtca     4020

tcctggagtt ccaggtttca tggggccccc agggaaccct gggccaccag gggcagatgg     4080

aattgcagga gctgctggac caccaggaat ccaagggtca cctgggaaag aaggccctcc     4140

tggcccccaa ggcccatctg gattacccgg aatcccagga gaagaaggca aagagggcag     4200

agatggaaag ccgggtcccc ctggagagcc gggcaaagca ggagagccag gtctaccagg     4260

accagagggt gcccgaggcc cacctggctt caagggacac acaggcgatt ctggtgcacc     4320

cggtccccgg ggagagtctg gtgccatggg gcttcctggt caggaagggt taccaggaaa     4380

agatggtgac actggaccca ctgggccaca gggtccccaa ggaccaaggg gcccaccggg     4440

caagaatgga tcaccgggat ctccaggaga gcctggccct tcaggaaccc ctggccagaa     4500

aggaagcaaa ggggaaaatg gcagcccagg acttcctggc ttcctgggtc cccgtgggcc     4560

tccgggagaa ccaggagaga aaggagtccc aggcaaggag ggggtccctg ggaagcctgg     4620

agagcctgga ttcaaaggag aaaggggaga tcctgggatc aaaggtgaca aaggacctcc     4680

tggtggaaaa ggccagcctg gggaccctgg aatcccaggc cacaaaggcc acacaggcct     4740

gatgggtccc caaggactac ctggggagaa tggaccagtt ggacccccag ggcctccagg     4800

ccagccggga tttccaggac tgagggggga gtctccatcc atggaaaccc tgcgtcggct     4860

tattcaagaa gagctgggga agcagcttga aaccagactc gcctacctcc tggcccagat     4920

gcccccggcg tacatgaagt catctcaagg cagacctggg cccccagggc cccctggaaa     4980

agatgggctt ccaggccggg ccggccccat gggggagcca ggtcgtcctg ggcagggggg     5040

tctggaagga ccctctggac ccataggtcc caaaggtgag cgaggagcca aaggtgaccc     5100

aggtgcacct ggagttggcc tccgaggcga gatgggaccc cctggaatcc caggtcaacc     5160

cggggaacct ggctatgcta aagatggact tcctgggatc cctggccctc aaggggagac     5220

aggaccagct ggacatcctg gcctcccagg acctcccggt cccccaggcc aatgtgaccc     5280

ttcccagtgt gcctacttcg ccagccttgc tgcccggccg ggtaatgtga agggtcccta     5340

aaggactctg gaaagccaga agactgcagt ggatttctga aacttgaact cagagcccag     5400

tgggaagcca gaggtcttga aagacttcag ccatgtgttc cttttttttt tctttctttt     5460

atcgtttgct ttttgtttta ttttcttgag agacctcaaa attattaaat ccaacagacg     5520

ctgccggtcg gtcagattat tattaatatt attgttgttg ttaattatta ttattatttc     5580

atatgctgat gctttgtgag ttcttttcca ctcctttaaa gttgggaaaa cttgattcgt     5640

ggggcaggag attgtttctt cattcttctg acagccccca tctgacgcgt aactgcccat     5700

tttaaggaaa ctcttggtgc tacaaaaccc tgaccagaca cttggcaaat ttacctcttt     5760

cttcaaaaga aaaactttaa gaaaatgagc caatgggctt cattctcagt catgcccgga     5820

gatcacccag gagaaataat acaaacacca ccactgtcca gagagagtaa agaagcagaa     5880

agagaaagaa tttgcaacca tgaggaatgt tcccacctcc cgacgggacg tgcatttgga     5940

aaacacagaa tcagccctca gggtgcactc cagccacctc agtgctctaa gctcacagaa     6000

gtgaaataat gtctgtgggt tggcaatggc tttgtgggat catatgtctt ggccaaagat     6060

gggaaaacct atgttgaaga ggcagccctt gagtgttaat ttgtcttcta aactgtgtaa     6120

ggccccttca agttcctctt gttggtttca attatattaa ttataaaaca agtggatgtg     6180

gtgaccatcc acttgtgttt ccctaatgat gggcagttgg ccagggcact gaccagagct     6240

gggaaatttg tatctccaag gcggctctgt ctctgaaata aatggcatca agtgcatgtg     6300

tgtatgcgac atgccctgcc tgaacaggtg ctcaataaat ccaagtttcc ttctcttgaa     6360

aaaaa                                                                 6365


<210>  2049
<211>  5490
<212>  DNA
<213>  homo sapiens

<400>  2049
ggctgagttt tatgacgggc ccggtgctga agggcaggga acaacttgat ggtgctactt       60

tgaactgctt ttcttttctc ctttttgcac aaagagtctc atgtctgata tttagacatg      120

atgagctttg tgcaaaaggg gagctggcta cttctcgctc tgcttcatcc cactattatt      180

ttggcacaac aggaagctgt tgaaggagga tgttcccatc ttggtcagtc ctatgcggat      240

agagatgtct ggaagccaga accatgccaa atatgtgtct gtgactcagg atccgttctc      300

tgcgatgaca taatatgtga cgatcaagaa ttagactgcc ccaacccaga aattccattt      360

ggagaatgtt gtgcagtttg cccacagcct ccaactgctc ctactcgccc tcctaatggt      420

caaggacctc aaggccccaa gggagatcca ggccctcctg gtattcctgg gagaaatggt      480

gaccctggta ttccaggaca accagggtcc cctggttctc ctggcccccc tggaatctgt      540

gaatcatgcc ctactggtcc tcagaactat tctccccagt atgattcata tgatgtcaag      600

tctggagtag cagtaggagg actcgcaggc tatcctggac cagctggccc cccaggccct      660

cccggtcccc ctggtacatc tggtcatcct ggttcccctg gatctccagg ataccaagga      720

ccccctggtg aacctgggca agctggtcct tcaggccctc caggacctcc tggtgctata      780

ggtccatctg gtcctgctgg aaaagatgga gaatcaggta gacccggacg acctggagag      840

cgaggattgc ctggacctcc aggtatcaaa ggtccagctg ggatacctgg attccctggt      900

atgaaaggac acagaggctt cgatggacga aatggagaaa agggtgaaac aggtgctcct      960

ggattaaagg gtgaaaatgg tcttccaggc gaaaatggag ctcctggacc catgggtcca     1020

agaggggctc ctggtgagcg aggacggcca ggacttcctg gggctgcagg tgctcggggt     1080

aatgacggtg ctcgaggcag tgatggtcaa ccaggccctc ctggtcctcc tggaactgcc     1140

ggattccctg gatcccctgg tgctaagggt gaagttggac ctgcagggtc tcctggttca     1200

aatggtgccc ctggacaaag aggagaacct ggacctcagg gacacgctgg tgctcaaggt     1260

cctcctggcc ctcctgggat taatggtagt cctggtggta aaggcgaaat gggtcccgct     1320

ggcattcctg gagctcctgg actgatggga gcccggggtc ctccaggacc agccggtgct     1380

aatggtgctc ctggactgcg aggtggtgca ggtgagcctg gtaagaatgg tgccaaagga     1440

gagcccggac cacgtggtga acgcggtgag gctggtattc caggtgttcc aggagctaaa     1500

ggcgaagatg gcaaggatgg atcacctgga gaacctggtg caaatgggct tccaggagct     1560

gcaggagaaa ggggtgcccc tgggttccga ggacctgctg gaccaaatgg catcccagga     1620

gaaaagggtc ctgctggaga gcgtggtgct ccaggccctg cagggcccag aggagctgct     1680

ggagaacctg gcagagatgg cgtccctgga ggtccaggaa tgaggggcat gcccggaagt     1740

ccaggaggac caggaagtga tgggaaacca gggcctcccg gaagtcaagg agaaagtggt     1800

cgaccaggtc ctcctgggcc atctggtccc cgaggtcagc ctggtgtcat gggcttcccc     1860

ggtcctaaag gaaatgatgg tgctcctggt aagaatggag aacgaggtgg ccctggagga     1920

cctggccctc agggtcctcc tggaaagaat ggtgaaactg gacctcaggg acccccaggg     1980

cctactgggc ctggtggtga caaaggagac acaggacccc ctggtccaca aggattacaa     2040

ggcttgcctg gtacaggtgg tcctccagga gaaaatggaa aacctgggga accaggtcca     2100

aagggtgatg ccggtgcacc tggagctcca ggaggcaagg gtgatgctgg tgcccctggt     2160

gaacgtggac ctcctggatt ggcaggggcc ccaggactta gaggtggagc tggtccccct     2220

ggtcccgaag gaggaaaggg tgctgctggt cctcctgggc cacctggtgc tgctggtact     2280

cctggtctgc aaggaatgcc tggagaaaga ggaggtcttg gaagtcctgg tccaaagggt     2340

gacaagggtg aaccaggcgg tccaggtgct gatggtgtcc cagggaaaga tggcccaagg     2400

ggtcctactg gtcctattgg tcctcctggc ccagctggcc agcctggaga taagggtgaa     2460

ggtggtgccc ccggacttcc aggtatagct ggacctcgtg gtagccctgg tgagagaggt     2520

gaaactggcc ctccaggacc tgctggtttc cctggtgctc ctggacagaa tggtgaacct     2580

ggtggtaaag gagaaagagg ggctccgggt gagaaaggtg aaggaggccc tcctggagtt     2640

gcaggacccc ctggaggttc tggacctgct ggtcctcctg gtccccaagg tgtcaaaggt     2700

gaacgtggca gtcctggtgg acctggtgct gctggcttcc ctggtgctcg tggtcttcct     2760

ggtcctcctg gtagtaatgg taacccagga cccccaggtc ccagcggttc tccaggcaag     2820

gatgggcccc caggtcctgc gggtaacact ggtgctcctg gcagccctgg agtgtctgga     2880

ccaaaaggtg atgctggcca accaggagag aagggatcgc ctggtgccca gggcccacca     2940

ggagctccag gcccacttgg gattgctggg atcactggag cacggggtct tgcaggacca     3000

ccaggcatgc caggtcctag gggaagccct ggccctcagg gtgtcaaggg tgaaagtggg     3060

aaaccaggag ctaacggtct cagtggagaa cgtggtcccc ctggacccca gggtcttcct     3120

ggtctggctg gtacagctgg tgaacctgga agagatggaa accctggatc agatggtctt     3180

ccaggccgag atggatctcc tggtggcaag ggtgatcgtg gtgaaaatgg ctctcctggt     3240

gcccctggcg ctcctggtca tccaggccca cctggtcctg tcggtccagc tggaaagagt     3300

ggtgacagag gagaaagtgg ccctgctggc cctgctggtg ctcccggtcc tgctggttcc     3360

cgaggtgctc ctggtcctca aggcccacgt ggtgacaaag gtgaaacagg tgaacgtgga     3420

gctgctggca tcaaaggaca tcgaggattc cctggtaatc caggtgcccc aggttctcca     3480

ggccctgctg gtcagcaggg tgcaatcggc agtccaggac ctgcaggccc cagaggacct     3540

gttggaccca gtggacctcc tggcaaagat ggaaccagtg gacatccagg tcccattgga     3600

ccaccagggc ctcgaggtaa cagaggtgaa agaggatctg agggctcccc aggccaccca     3660

gggcaaccag gccctcctgg acctcctggt gcccctggtc cttgctgtgg tggtgttgga     3720

gccgctgcca ttgctgggat tggaggtgaa aaagctggcg gttttgcccc gtattatgga     3780

gatgaaccaa tggatttcaa aatcaacacc gatgagatta tgacttcact caagtctgtt     3840

aatggacaaa tagaaagcct cattagtcct gatggttctc gtaaaaaccc cgctagaaac     3900

tgcagagacc tgaaattctg ccatcctgaa ctcaagagtg gagaatactg ggttgaccct     3960

aaccaaggat gcaaattgga tgctatcaag gtattctgta atatggaaac tggggaaaca     4020

tgcataagtg ccaatccttt gaatgttcca cggaaacact ggtggacaga ttctagtgct     4080

gagaagaaac acgtttggtt tggagagtcc atggatggtg gttttcagtt tagctacggc     4140

aatcctgaac ttcctgaaga tgtccttgat gtgcagctgg cattccttcg acttctctcc     4200

agccgagctt cccagaacat cacatatcac tgcaaaaata gcattgcata catggatcag     4260

gccagtggaa atgtaaagaa ggccctgaag ctgatggggt caaatgaagg tgaattcaag     4320

gctgaaggaa atagcaaatt cacctacaca gttctggagg atggttgcac gaaacacact     4380

ggggaatgga gcaaaacagt ctttgaatat cgaacacgca aggctgtgag actacctatt     4440

gtagatattg caccctatga cattggtggt cctgatcaag aatttggtgt ggacgttggc     4500

cctgtttgct ttttataaac caaactctat ctgaaatccc aacaaaaaaa atttaactcc     4560

atatgtgttc ctcttgttct aatcttgtca accagtgcaa gtgaccgaca aaattccagt     4620

tatttatttc caaaatgttt ggaaacagta taatttgaca aagaaaaatg atacttctct     4680

ttttttgctg ttccaccaaa tacaattcaa atgctttttg ttttattttt ttaccaattc     4740

caatttcaaa atgtctcaat ggtgctataa taaataaact tcaacactct ttatgataac     4800

aacactgtgt tatattcttt gaatcctagc ccatctgcag agcaatgact gtgctcacca     4860

gtaaaagata acctttcttt ctgaaatagt caaatacgaa attagaaaag ccctccctat     4920

tttaactacc tcaactggtc agaaacacag attgtattct atgagtccca gaagatgaaa     4980

aaaattttat acgttgataa aacttataaa tttcattgat taatctcctg gaagattggt     5040

ttaaaaagaa aagtgtaatg caagaattta aagaaatatt tttaaagcca caattatttt     5100

aatattggat atcaactgct tgtaaaggtg ctcctctttt ttcttgtcat tgctggtcaa     5160

gattactaat atttgggaag gctttaaaga cgcatgttat ggtgctaatg tactttcact     5220

tttaaactct agatcagaat tgttgacttg cattcagaac ataaatgcac aaaatctgta     5280

catgtctccc atcagaaaga ttcattggca tgccacaggg gattctcctc cttcatcctg     5340

taaaggtcaa caataaaaac caaattatgg ggctgctttt gtcacactag catagagaat     5400

gtgttgaaat ttaactttgt aagcttgtat gtggttgttg atcttttttt tccttacaga     5460

cacccataat aaaatatcat attaaaattc                                      5490


<210>  2050
<211>  6545
<212>  DNA
<213>  homo sapiens

<400>  2050
aggtctccgc ttggagccgc cgcacccggg acggtgcgta gcgctggaag tccggccttc       60

cgagagctag ctgtccgccg cggcccccgc acgccgggca gccgtccctc gccgcctcgg      120

gcgcgccacc atggggcccc ggctcagcgt ctggctgctg ctgctgcccg ccgcccttct      180

gctccacgag gagcacagcc gggccgctgc gaagggtggc tgtgctggct ctggctgtgg      240

caaatgtgac tgccatggag tgaagggaca aaagggtgaa agaggcctcc cggggttaca      300

aggtgtcatt gggtttcctg gaatgcaagg acctgagggg ccacagggac caccaggaca      360

aaagggtgat actggagaac caggactacc tggaacaaaa gggacaagag gacctccggg      420

agcatctggc taccctggaa acccaggact tcccggaatt cctggccaag acggcccgcc      480

aggcccccca ggtattccag gatgcaatgg cacaaagggg gagagagggc cgctcgggcc      540

tcctggcttg cctggtttcg ctggaaatcc cggaccacca ggcttaccag ggatgaaggg      600

tgatccaggt gagatacttg gccatgtgcc cgggatgctg ttgaaaggtg aaagaggatt      660

tcccggaatc ccagggactc caggcccacc aggactgcca gggcttcaag gtcctgttgg      720

gcctccagga tttaccggac caccaggtcc cccaggccct cccggccctc caggtgaaaa      780

gggacaaatg ggcttaagtt ttcaaggacc aaaaggtgac aagggtgacc aaggggtcag      840

tgggcctcca ggagtaccag gacaagctca agttcaagaa aaaggagact tcgccaccaa      900

gggagaaaag ggccaaaaag gtgaacctgg atttcagggg atgccagggg tcggagagaa      960

aggtgaaccc ggaaaaccag gacccagagg caaacccgga aaagatggtg acaaagggga     1020

aaaagggagt cccggttttc ctggtgaacc cgggtaccca ggactcatag gccgccaggg     1080

cccgcaggga gaaaagggtg aagcaggtcc tcctggccca cctggaattg ttataggcac     1140

aggacctttg ggagaaaaag gagagagggg ctaccctgga actccggggc caagaggaga     1200

gccaggccca aaaggtttcc caggactacc aggccaaccc ggacctccag gcctccctgt     1260

acctgggcag gctggtgccc ctggcttccc tggtgaaaga ggagaaaaag gtgaccgagg     1320

atttcctggt acatctctgc caggaccaag tggaagagat gggctcccgg gtcctcctgg     1380

ttcccctggg ccccctgggc agcctggcta cacaaatgga attgtggaat gtcagcccgg     1440

acctccaggt gaccagggtc ctcctggaat tccagggcag ccaggattta taggcgaaat     1500

tggagagaaa ggtcaaaaag gagagagttg cctcatctgt gatatagacg gatatcgggg     1560

gcctcccggg ccacagggac ccccgggaga aataggtttc ccagggcagc caggggccaa     1620

gggcgacaga ggtttgcctg gcagagatgg tgttgcagga gtgccaggcc ctcaaggtac     1680

accagggctg ataggccagc caggagccaa gggggagcct ggtgagtttt atttcgactt     1740

gcggctcaaa ggtgacaaag gagacccagg ctttccagga cagcccggca tgccagggag     1800

agcgggttct cctggaagag atggccatcc gggtcttcct ggccccaagg gctcgccggg     1860

ttctgtagga ttgaaaggag agcgtggccc ccctggagga gttggattcc caggcagtcg     1920

tggtgacacc ggcccccctg ggcctccagg atatggtcct gctggtccca ttggtgacaa     1980

aggacaagca ggctttcctg gaggccctgg atccccaggc ctgccaggtc caaagggtga     2040

accaggaaaa attgttcctt taccaggccc ccctggagca gaaggactgc cggggtcccc     2100

aggcttccca ggtccccaag gagaccgagg ctttcccgga accccaggaa ggccaggcct     2160

gccaggagag aagggcgctg tgggccagcc aggcattgga tttccagggc cccccggccc     2220

caaaggtgtt gacggcttac ctggagacat ggggccaccg gggactccag gtcgcccggg     2280

atttaatggc ttacctggga acccaggtgt gcagggccag aagggagagc ctggagttgg     2340

tctaccggga ctcaaaggtt tgccaggtct tcccggcatt cctggcacac ccggggagaa     2400

ggggagcatt ggggtaccag gcgttcctgg agaacatgga gcgatcggac cccctgggct     2460

tcaggggatc agaggtgaac cgggacctcc tggattgcca ggctccgtgg ggtctccagg     2520

agttccagga ataggccccc ctggagctag gggtccccct ggaggacagg gaccaccggg     2580

gttgtcaggc cctcctggaa taaaaggaga gaagggtttc cccggattcc ctggactgga     2640

catgccgggc cctaaaggag ataaaggggc tcaaggactc cctggcataa cgggacagtc     2700

ggggctccct ggccttcctg gacagcaggg ggctcctggg attcctgggt ttccaggttc     2760

caagggagaa atgggcgtca tggggacccc cgggcagccg ggctcaccag gaccagtggg     2820

tgctcctgga ttaccgggtg aaaaagggga ccatggcttt ccgggctcct caggacccag     2880

gggagaccct ggcttgaaag gtgataaggg ggatgtcggt ctccctggca agcctggctc     2940

catggataag gtggacatgg gcagcatgaa gggccagaaa ggagaccaag gagagaaagg     3000

acaaattgga ccaattggtg agaagggatc ccgaggagac cctgggaccc caggagtgcc     3060

tggaaaggac gggcaggcag gacagcctgg gcagccagga cctaaaggtg atccaggtat     3120

aagtggaacc ccaggtgctc caggacttcc gggaccaaaa ggatctgttg gtggaatggg     3180

cttgccagga acacctggag agaaaggtgt gcctggcatc cctggcccac aaggttcacc     3240

tggcttacct ggagacaaag gtgcaaaagg agagaaaggg caggcaggcc cacctggcat     3300

aggcatccca gggctgcgag gtgaaaaggg agatcaaggg atagcgggtt tcccaggaag     3360

ccctggagag aagggagaaa aaggaagcat tgggatccca ggaatgccag ggtccccagg     3420

ccttaaaggg tctcccggga gtgttggcta tccaggaagt cctgggctac ctggagaaaa     3480

aggtgacaaa ggcctcccag gattggatgg catccctggt gtcaaaggag aagcaggtct     3540

tcctgggact cctggcccca caggcccagc tggccagaaa ggggagccag gcagtgatgg     3600

aatcccgggg tcagcaggag agaagggtga accaggtcta ccaggaagag gattcccagg     3660

gtttccaggg gccaaaggag acaaaggttc aaagggtgag gtgggtttcc caggattagc     3720

cgggagccca ggaattcctg gatccaaagg agagcaagga ttcatgggtc ctccggggcc     3780

ccagggacag ccggggttac cgggatcccc aggccatgcc acggaggggc ccaaaggaga     3840

ccgcggacct cagggccagc ctggcctgcc aggacttccg ggacccatgg ggcctccagg     3900

gcttcctggg attgatggag ttaaaggtga caaaggaaat ccaggctggc caggagcacc     3960

cggtgtccca gggcccaagg gagaccctgg attccagggc atgcctggta ttggtggctc     4020

tccaggaatc acaggctcta agggtgatat ggggcctcca ggagttccag gatttcaagg     4080

tccaaaaggt cttcctggcc tccagggaat taaaggtgat caaggcgatc aaggcgtccc     4140

gggagctaaa ggtctcccgg gtcctcctgg ccccccaggt ccttacgaca tcatcaaagg     4200

ggagcccggg ctccctggtc ctgagggccc cccagggctg aaagggcttc agggactgcc     4260

aggcccgaaa ggccagcaag gtgttacagg attggtgggt atacctggac ctccaggtat     4320

tcctgggttt gacggtgccc ctggccagaa aggagagatg ggacctgccg ggcctactgg     4380

tccaagagga tttccaggtc caccaggccc cgatgggttg ccaggatcca tggggccccc     4440

aggcacccca tctgttgatc acggcttcct tgtgaccagg catagtcaaa caatagatga     4500

cccacagtgt ccttctggga ccaaaattct ttaccacggg tactctttgc tctacgtgca     4560

aggcaatgaa cgggcccatg gccaggactt gggcacggcc ggcagctgcc tgcgcaagtt     4620

cagcacaatg cccttcctgt tctgcaatat taacaacgtg tgcaactttg catcacgaaa     4680

tgactactcg tactggctgt ccacccctga gcccatgccc atgtcaatgg cacccatcac     4740

gggggaaaac ataagaccat ttattagtag gtgtgctgtg tgtgaggcgc ctgccatggt     4800

gatggccgtg cacagccaga ccattcagat cccaccgtgc cccagcgggt ggtcctcgct     4860

gtggatcggc tactcttttg tgatgcacac cagcgctggt gcagaaggct ctggccaagc     4920

cctggcgtcc cccggctcct gcctggagga gtttagaagt gcgccattca tcgagtgtca     4980

cggccgtggg acctgcaatt actacgcaaa cgcttacagc ttttggctcg ccaccataga     5040

gaggagcgag atgttcaaga agcctacgcc gtccaccttg aaggcagggg agctgcgcac     5100

gcacgtcagc cgctgccaag tctgtatgag aagaacataa tgaagcctga ctcagctaat     5160

gtcacaacat ggtgctactt cttcttcttt ttgttaacag caacgaaccc tagaaatata     5220

tcctgtgtac ctcactgtcc aatatgaaaa ccgtaaagtg ccttatagga atttgcgtaa     5280

ctaacacacc ctgcttcatt gacctctact tgctgaagga gaaaaagaca gcgataagct     5340

ttcaatagtg gcataccaaa tggcactttt gatgaaataa aatatcaata ttttctgcaa     5400

tccaatgcac tgatgtgtga agtgagaact ccatcagaaa accaaagggt gctaggaggt     5460

gtgggtgcct tccatactgt ttgcccattt tcattcttgt attataatta attttctacc     5520

cccagagata aatgtttgtt tatatcactg tctagctgtt tcaaaattta ggtcccttgg     5580

tctgtacaaa taatagcaat gtaaaaatgg ttttttgaac ctccaaatgg aattacagac     5640

tcagtagcca tatcttccaa ccccccagta taaatttctg tctttctgct atgtgtggta     5700

ctttgcagct gcttttgcag aaatcacaat tttcctgtgg aataaagatg gtccaaaaat     5760

agtcaaaaat taaatatata tatatattag taatttatat agatgtcagc aattaggcag     5820

atcaaggttt agtttaactt ccactgttaa aataaagctt acatagtttt cttcctttga     5880

aagactgtgc tgtcctttaa cataggtttt taaagactag gatattgaat gtgaaacatc     5940

cgttttcatt gttcacttct aaaccaaaaa ttatgtgttg ccaaaaccaa acccaggttc     6000

atgaatatgg tgtctattat agtgaaacat gtactttgag cttattgttt ttattctgta     6060

ttaaatattt tcagggtttt aaacactaat cacaaactga atgacttgac ttcaaaagca     6120

acaaccttaa aggccgtcat ttcattagta ttcctcattc tgcatcctgg cttgaaaaac     6180

agctctgttg aatcacagta tcagtatttt cacacgtaag cacattcggg ccatttccgt     6240

ggtttctcat gagctgtgtt cacagacctc agcagggcat cgcatggacc gcaggagggc     6300

agattcggac cactaggcct gaaatgacat ttcactaaaa gtctccaaaa catttctaag     6360

actactaagg ccttttatgt aatttcttta aatgtgtatt tcttaagaat tcaaatttgt     6420

aataaaacta tttgtataaa aattaagctt ttattaattt gttgctagta ttgccacaga     6480

cgcattaaaa gaaacttact gcacaagctg ctaataaatt tgtaagcttt gcatacctta     6540

gatta                                                                 6545


<210>  2051
<211>  10974
<212>  DNA
<213>  homo sapiens

<400>  2051
gattcacagg gcctctgagc attatccccc atactcctcc ccatcattct ccacccagct       60

gttggagcca tctgtctgat caccttggac tccatagtac actggggcaa agcacagccc      120

cagtttctgg aggcagatgg gtaaccagga aaaggcatga atgagggggc cccaggagac      180

agtgacttag agactgaggc aagagtgccg tggtcaatca tgggtcattg tcttcgaact      240

ggacaggcca gaatgtctgc cacacccaca cctgcaggtg aaggagccag aagctcttca      300

acctgtagct ccctgagcag gctgttctgg tctcaacttg agcacataaa ctgggatgga      360

gccacagcca agaactttat taatttaagg gagttcttct cttttctgct ccctgcattg      420

agaaaagctc aaattgaaat tattccatgc aagatctgtg gagacaaatc atcaggaatc      480

cattatggtg tcattacatg tgaaggctgc aagggctttt tcaggagaag tcagcaaagc      540

aatgccacct actcctgtcc tcgtcagaag aactgtttga ttgatcgaac cagtagaaac      600

cgctgccaac actgtcgatt acagaaatgc cttgccgtag ggatgtctcg agatgctgta      660

aaatttggcc gaatgtcaaa aaagcagaga gacagcttgt atgcagaagt acagaaacac      720

cggatgcagc agcagcagcg cgaccaccag cagcagcctg gagaggctga gccgctgacg      780

cccacctaca acatctcggc caacgggctg acggaacttc acgacgacct cagtaactac      840

attgacgggc acacccctga ggggagtaag gcagactccg ccgtcagcag cttctacctg      900

gacatacagc cttccccaga ccagtcaggt cttgatatca atggaatcaa accagaacca      960

atatgtgact acacaccagc atcaggcttc tttccctact gttcgttcac caacggcgag     1020

acttccccaa ctgtgtccat ggcagaatta gaacaccttg cacagaatat atctaaatcg     1080

catctggaaa cctgccaata cttgagagaa gagctccagc agataacgtg gcagaccttt     1140

ttacaggaag aaattgagaa ctatcaaaac aagcagcggg aggtgatgtg gcaattgtgt     1200

gccatcaaaa ttacagaagc tatacagtat gtggtggagt ttgccaaacg cattgatgga     1260

tttatggaac tgtgtcaaaa tgatcaaatt gtgcttctaa aagcaggttc tctagaggtg     1320

gtgtttatca gaatgtgccg tgcctttgac tctcagaaca acaccgtgta ctttgatggg     1380

aagtatgcca gccccgacgt cttcaaatcc ttaggttgtg aagactttat tagctttgtg     1440

tttgaatttg gaaagagttt atgttctatg cacctgactg aagatgaaat tgcattattt     1500

tctgcatttg tactgatgtc agcagatcgc tcatggctgc aagaaaaggt aaaaattgaa     1560

aaactgcaac agaaaattca gctagctctt caacacgtcc tacagaagaa tcaccgagaa     1620

gatggaatac taacaaagtt aatatgcaag gtgtctacat taagagcctt atgtggacga     1680

catacagaaa agctaatggc atttaaagca atatacccag acattgtgcg acttcatttt     1740

cctccattat acaaggagtt gttcacttca gaatttgagc cagcaatgca aattgatggg     1800

taaatgttat cacctaagca cttctagaat gtctgaagta caaacatgaa aaacaaacaa     1860

aaaaattaac cgagacactt tatatggccc tgcacagacc tggagcgcca cacactgcac     1920

atcttttggt gatcggggtc aggcaaagga ggggaaacaa tgaaaacaaa taaaagttga     1980

acttgttttt ctcatgcata tgatttccat tatgcctaca gatatggacc ctttttctgt     2040

cttgacttct tgatcattga cctctgttta caacaggagg agggtactaa agtcggagga     2100

tttccttttc ttgtagctca ctgcccacag actttctaca gagtcaccaa tctgtcagta     2160

acaacagaga gtccagcaat aatcggtgac tggtgtgcat agcggaggtt gcggcattac     2220

tttgcacaac tagctctttg tttcatgaag gaagttttta ttttttcacc gattattgcc     2280

agtccgcagg atggcatgaa aagggtccat agcagtagca acaatagcat tataatatat     2340

tacagggtaa atgggcatga agactatata tagctaaaag agatattgtt tatatattgt     2400

tttaagtaat ataaaatgta gttactggtg tagcttttcc tgttgaattg ataaggcact     2460

ttcattttgc acctttttct ttaaattaaa tgctagcgtg ttcactgtcg tgtcgcatgt     2520

gcaccagaaa cacaagttta actgagaagg cttggaaggt acgttgggag gtatttatgc     2580

tgctgtttac aaaattattt ttaagagact ggctggtcat atctagaaat caccacgttg     2640

gatttttttt ttaacatgtg aatttggaat tagaaacgga actctcccta aattatactt     2700

tgctttttgg taagtttaat gatagatgtg tttatgcttc atacaaagtt gaatgattga     2760

ttggcgtggt ggacatatac catcatgctc attttttttt tttaaagctt tttaaaatgc     2820

cacctcatgg aggcgagggg gaggagaagc tcattttaca caattcagta gttaaatatg     2880

gactcggtct caacttggaa ttcttatgct ttgagaacaa atcaacaacc agaatattta     2940

ttggaatcta gcttttatta taagaaggac ccaaagatta tatcctgagc aaatgcacac     3000

tccccatgtg aggacatgaa gtatttactt tgtgaatgtt tatgttcttg gtataatcta     3060

ggaaccctat gagtttatct cagagtgaac taattctaga tttgttgtca atagatgcta     3120

taattcaaga atgttgctct ccatatttga aaaacgatgg ataggagggt gagggaagca     3180

tacaatgttg aaccagtttc tcttatttaa atattaaata ctttaagcct ttaaagtgaa     3240

gttgatgcta gctgcaaaca tttactcttg tatttatctt cactaggaaa ctgtggactg     3300

taatttattt tattaaatat ttagaagatt atttggcttg tgtgttcagg tgagaaatac     3360

tgagttgttt ttgtttaatt tcatggtttt ttttttttta atgatcccta gtgggggaag     3420

gggaaaggaa tagtctgata aacagatgtg catattttaa aaacaagtga ccttttggga     3480

atgtaggcat ttagacgatg attttagtcg cactaggggt gggattcaaa ctactggtca     3540

aagaccattt tgtacagaaa agggaacatc tccgatgggt gttaaggtag gagtttccat     3600

gcagcccttt atgtctgaga aatagtctcc tctgccattg gggtccctgc ggaatcttct     3660

acaggaattg cagctcttca cgtcatgcta ggttaccagc atgggcttcc cagagcactt     3720

cactctgttt ctaactccac tgacttttct gacttgtttc ttgagggact tggaaaaggg     3780

gaaggtatta ttcacacaga tgtgtgtatg aagcctaaat aacatccaac tttttttcca     3840

aaaacatagt aagagtttaa ccataaatag aagagtaata ttcctttaaa tttcttacag     3900

gcatgtaaaa ttttatgtgt ttatagagag atgctaactg tcagcatata gtatttatat     3960

tggggcaaga agggttaaat caaatcttta atttaagtaa gcatagttcc tttaaagatc     4020

agtagtattt atactctgaa aagagtacca agcttagttc agttatttat tcatccattt     4080

tttttctatt gtttctcctc tggggggaaa tggtgttttg tttttgtttg agttttgtgt     4140

tttagttttt tggttttggt tttgttttgt ttttttgtca ttcagattca ctaaatttgg     4200

ggatggtttt attaaagtat attaacttct ttttaaccaa agctttctga atatgaccag     4260

cctcaggtgc tagcgcatta aagagcaact aaacctaatt ccagtgtcga tttgtgaaat     4320

aataaaagct aattgaattt ctctaagggt gagagagaac ataatgatga acttaaaaag     4380

aaattccttt tcccagaagg gattctgcat gtacctacaa acaatcatgc tctaaccaca     4440

gtaatagtca tgccatggtg acattgcttt tacggtaaac caagataggt aatatgatgc     4500

ttcttcccag gtgtttctga aagaaaagca gcggtggagc ttaagagcca agtccactga     4560

ttgacataat aggatggaat tgtagacaga gacatgctcc atgaaacaag gaaacaactg     4620

actactattt ggatctaagt tgggatctga tgttaaacaa taaattcagt ttaaaaaaaa     4680

tatggagctc agaaaaggat gtgaaaaact ttgcattttc ctttcttcat tattacaaaa     4740

acacctatgt gatgacataa aatacttggg tgatatcaga acaattatcc ttaatagttt     4800

ttataattaa agtttcctaa acttcagtct ccaatagtct tttaaggatt ggaaccacat     4860

cactgtcagc cccgctgcta caatgccttt gtacaatttt tttacataag gcaaataagg     4920

cttttgtaca aagcctgaat accttctgtt ccaatggtgt ccaaatggtt attatattgt     4980

gaaaaacctg gccttggtca caatgcaaac aaaagtacag atgaaagtgc tttttggaca     5040

gtttgcaaat tgtgttaaag ctacggattt tttttaaagt gttcagcatc ttaacgtgta     5100

ttaaagctat ggattttttt ttaaagtctt cagcatccta attcaccctt tctaacttaa     5160

gaaaaacatg acttaagaca ctgcttctaa gtttggttgt tctttatagt gtggataccc     5220

agttatctgt gagcgtatgg gggtgggctg agggtcaggt gaggaaggag tgtgtgtgtg     5280

tgtgtgtgtg tgtgtgtgtg tgtgtgtgat ttgcatgtgt atgatgtgtg tgcgtcggac     5340

cgcttctagg ctactaagtg tcaatggaaa agaaaatgta ttcaaaatac ttaaatcaaa     5400

actagaagat ggggaaaaaa agatttattc tatacaaagc cttgtctgga ccactttaga     5460

gagacttcta tttttttaac ccttctataa atatttgatg gcacttgaaa tattcctgca     5520

ataaaatgtg atttgtgtaa agaaaaaaag attttgtaat gtgaaacaaa gaaagaaagt     5580

aatgtaattt tctaaaaaaa aaaatacaaa caaacaaact ttgtattatt ttcttgatgg     5640

aatttgtcta tctgtctttg gaaaactttt tatttcattg aatgtgccat agtagaaatg     5700

tgtgttttta gttttagact aaggaatagc tagttgttgt gttccgacat tccaaaatgc     5760

aaaacaacct agtagtatct ttcatgaaaa ggtttaagta gtatgtaagc ttctctcatt     5820

gttgcttttt tgcacatgtt cttcattcct ctctagtgca atatgtacat agagcacttg     5880

cgggtgtacc ttgatccctc agggaaaaat acatatttgt acagtttttt ggggtttttt     5940

tgttttttgg ttttttttgt tttgcctttt gtttttggct aaggaatgtc gatcgaatca     6000

cttgttattg ttgaggggca gccagataat aatcctaaag ccactgtttc caacattgat     6060

tgtttaaatc atatgtcctt ccaatgctat tattttaaga taataataaa aagttatttt     6120

ctgacagttc tttgtgctga ctggtgaaaa acaagggtaa ataagcacct tataattgac     6180

ttactgtgaa tgacaatcca tcttggtatc aacgatagaa gccctatcat tttggagttg     6240

gggttaagag tcagaaacaa tgtgctcagg gatctcctaa aactcttaaa acagggtggc     6300

cagtactact gggacaaatt gtgtttttta ttattaataa taatgataat aatactatcc     6360

ctccaaggca caagtgaact atatagaact gcgtgtgtgt aaactcttta ctctcgtctc     6420

attttgttga gtttagaact tgatgtgctc gtcagtcttg tgtttcaaaa cactgaataa     6480

cttccaaagc aaagttatgc cagtgtgttc aaaagataaa ttaataatgt accagcaaag     6540

agcatcattc aaagtatagt ccttgcatat tccagttacc atttctctaa taattaaaat     6600

attcatgata aatatatata tagcatcata tgttaaaaac tatttcaaat tctacatatt     6660

aaggatgaaa attttaaaat ccagtaataa gaggagagac ctgcctatca gtacagtgat     6720

ataggtaaaa gatgaaatat gtttttaaaa taccagcaat taactattgt tttcatgggt     6780

tctcctctag aagcaaacca aaaattcctt catggaaaac aattcttact tctacatgtg     6840

tagtttatat ctgatgcatt acaagagcta atgtttaaag acaaaacaaa acctgcctgt     6900

atgacagcag caactcgagc caacatttag tgttacatgt tatatttttg aaataccgtt     6960

ttgttatcat attccacata ttactttcca taaagtcaga gaagttcaat gtaattgttg     7020

gctctgattc ttccaccttg ggatacacat tcacaagaag atttatatat tttcttacta     7080

tgatagagga acataatctg ggaaaacttc ccatgtctgt aagatgaaaa ggataccttt     7140

accatgttgt ttttgataat aaagaatatg gaaaatggta gaaatctctc ctctctatgt     7200

gtatttgtat atgtgtgtat acacacacac gttgacattt ttacataaca tgtgattgcc     7260

acttcttata aagttatgat atagaacccc atgaaaacaa ctttatatta tagatcaaat     7320

aatgtgccca gaaacgcaat tgcaacagta aatcttgatc tattggtaag agtctatgat     7380

acaggtcttc attctatccc taaacataat gttagtaaag aggttccatc agattgtatt     7440

atagagacct tcctattgct atttattttt aagagatgag aagactgact agcaatgtct     7500

ccacagtgca attggtttca cttctgggtc tgtctgtctg tttgtgtagg tgagatcagt     7560

gttgtcaggc tctcagaata atttttaaaa gaatccagaa gcctgacttc acaccaagta     7620

gccatcctag atgggcgggg gggatctcca tgttcaacca aaccctcaga acttagagca     7680

ataaatacat tcagtcattt atttataaat gaatgacaga atattcaatc caaatagaaa     7740

caaccttttg tcagtgatgc aacataacat ggagtcttat attgagaaag tgaatatgaa     7800

tattttaaat agatgcctag gaaatctgtg tttgctgttt acatttaatg tactttgcca     7860

cattagcagt accacacttc ttttactttc atccttctaa gaactaatga aagatagctt     7920

gctattagct ttgacatgtt gcacatgcca ttatgttgtt ctctaagaac aactaaattc     7980

tctccagtgt tcatgtgtga ttcctttttc atcattatta ctttaatgtg gatgaatact     8040

atttctagga acttgattat cactgaacag attgcatatg taaatgcaga taattcttga     8100

gcaatatagt gaaaatgatt tcacaaaaaa aatccatatg tactgtatac atcttcctga     8160

atccaaaatt ctcctgttat ccacacagtt tgaaatctca tattaaacag tggtaaattt     8220

ttaaacatta ggacattagc tggctgcttc tataaatgta cctgtattgt ctgcctgctc     8280

cttttgtgga gatgtgtttt tgtattggat gtttgggcca atgggaggct tcaagctaca     8340

acatattttc ccactttaaa taatatttaa catatgacaa accccagaca aggcttttaa     8400

tatgtataaa gaactgcagt gttaggtggt ttatttgcaa actgttttca gtgttgtcca     8460

tttttatggc acctttaaca atattcttgt ttccaaagta caaaaaaaat aggttaaata     8520

atctagccat aactgaatgt caagcaataa aacaaatgac ttttgtgcat agacttaaaa     8580

aatacaaatt ttagacatct gcatgtaaat gcaatctctt gtttactgct ttcttcaact     8640

tgagcaatcg attccttatt tactattaac ttaagaactt gtaacggcct gtaaacattt     8700

tctctcttac tcttctttca aatttacctg tccctgcttt tgagtcataa tatttaatgt     8760

tgttctgcac atctctatac agttaacttt ttggctttca ttctgtatag ataagaaaat     8820

gttatattat aaacagccta ctcagtgcaa atatttatct gtttatcaaa tccacaatat     8880

gctgtataat accggtttta ctatataatc tattttagac atagctgttt agaactagag     8940

tgtgctattt ttgtgttttt ctgatgtgtg gtgctagaca agttactttt gtgaacaaca     9000

aaaattatcc cttttattcc tagacaatac cacctttggg tcttgttaat ttcactgagt     9060

ataactatat atttgtatat atatacatat atatatatat ctacctatgc ccaactggca     9120

gctgtatcag agtgctggat ttgggacatg cttttctctt taaatacata atatcattat     9180

ataaattatt ctagagtgta tttaattagg ataaaattac ttccttagta tggatatttg     9240

acatctatag ggtgaatttg tttataaata tggctatatg gaaacttatt agcatttact     9300

ttatgtttgc tacttggctt tacagcatat ctcctaagct gaaaaataat ttgccaggcc     9360

ttcaagatcc taaagaaact tgtttaatgg agtaatatac ttttttttct tattaaggaa     9420

ttgtattact ggcacctaac acagttgtat tcttagctcc tattatagat aatgggcatt     9480

tacataaaat atcctagatg gcttgatggc agaataaacc tttcccctcc tacctgagtc     9540

atgagaagga tggagacgtc ctctgccata acatgggcca taaagcaaat tcgacatggg     9600

atgttctgtt tcagtatgac ctcaaccagt tccatgaact gagtgaagga ccttcatttt     9660

caaagttatt taataagtag cttaattaag cctttctacc cattctccca agatctactg     9720

gcattattga aaagcaaagt ttatcaaata tctaactaag gatgtagtta accttattaa     9780

atattgatta gaattgttct gtaatattac tgaatttgta agatctttag caaagatttt     9840

tgagcaattt ataaatgtag agcaaatgtt tctgtttact gcactttttg taactgaagg     9900

tgataaattc tcaagccatg attattggct tccatgcact gcaatattta tccacaattc     9960

tagacatttt ccatttttgt ggaagagttg ctgttacctt aattataaat gcaattgtgt    10020

ggttaatgag agctaatgct agtagttaac cttttaaagt ggattggcta cagttgaggg    10080

agaaatctct tttaatataa atcacatcat tccttaactg cctctcttgg aaagagattg    10140

aaaccttttt tttaaagcac gatttagcat cctaagcttc ctgagggtag agattgtatc    10200

tttttgcgtc tgcacaatgg ctagcacatg tcagcatttg acaattgtta aatgataaca    10260

agtgtgcccc aattaaaacg tttttcctgg gttgttttgt taaatttaca aagtaagcca    10320

agccttacgg ttaacattct cctctacaac caagtattaa agccacattt aaaaagacca    10380

catgaaatgc tgattctaat tgtgtgtagg tcttgaggat taagcacaca aatttcacaa    10440

acttctgttt gagtaaacaa actcagcctt ctgtaaatat acatgcaagt ttggaaacag    10500

taatactgta cctataaata tatgctgtct gttttgtgta cagtatgtaa aaactccttt    10560

tctgccacac taaaaatgca agccatttat gggaatccta aaactagtat tgaactaaaa    10620

ctttgctaat gatctttatt agaggatcgt ccaacttttc acttaccttg ggttttcttt    10680

tcaattcact cttacactag tctgcttatt tccagctgtt tattttattg agtcctgaat    10740

ttaaaaaaaa aatattttga ttcattttgt aaatacaagc tgtacaaaaa agagagattt    10800

aatgttgtct tttaaatact ccaattttca ttctaatatg aatgttgtta tattgtactt    10860

agaaactgta cctttaatat tacattacct ttattaaaag tgcattgaac acatcaattt    10920

tagatgtgct ttatgtactg ttatcctata ataaaacttc agcttctaat ggaa          10974


<210>  2052
<211>  4899
<212>  DNA
<213>  homo sapiens

<400>  2052
aatcggcggt gcccgcgcag ggtgctacgc cacgcccagc cgggccggcc gttcctaccg       60

gcctggtcca gcggacagcg gctgcagcgg gggcgccggc tgggagctgt ttttggaagg      120

aagaaagatg gaaagcggtg cagttctgct ggaatccaaa tcctccccat ttaacctact      180

gcatgagatg catgagcttc gcctcctggg tcacctgtgt gacgtgacag tcagcgtgga      240

gtatcagggt gtccgcaaag acttcatggc ccacaaggca gtgctggctg ccaccagcaa      300

gttttttaag gaagtgttcc ttaatgagaa gagtgtggat ggtactagga ctaatgtcta      360

cttaaatgaa gtgcaggttg ctgactttgc ttcatttctt gagtttgtct acactgcaaa      420

ggtacaggtg gaagaagatc gggtgcagcg aatgctggaa gtggctgaaa agctgaaatg      480

tttggattta tcagaaactt gttttcaatt aaagaaacag atgttagagt cagtactttt      540

ggagttgcaa aatttctcag agtctcagga ggtggaggtg agcagtggct cccaagttag      600

tgctgctcct gcccccaggg caagtgtggc caccgatggc cctcacccca gtggtctcac      660

ggattccttg gactacccag gagagagagc cagcaatggc atgtcttcag atttgccacc      720

gaagaagtcc aaggacaaac tagacaagaa gaaagaggta gttaaacctc cctaccctaa      780

aatcaggaga gctagtggaa ggctggctgg gaggaaggtc tttgtggaga tccctaaaaa      840

gaaatatacg agaagactcc gagagcagca gaaaactgct gagggtgatg tgggggacta      900

caggtgtccc caggaccaaa gcccggacag ggtgggcacg gagatggagc aggtttccaa      960

aaatgagggt tgccaggcag gtgctgagtt ggaggaattg tcaaagaaag cagggccgga     1020

ggaggaagag gaggaggagg aggaggacga agaaggggag aagaagaaga gcaactttaa     1080

gtgcagcatt tgcgagaagg cgtttctgta tgagaagagc ttcctgaagc acagcaagca     1140

ccgccacggc gtggccaccg aggtggtgta ccgctgcgac acctgcggcc agaccttcgc     1200

caaccgctgc aacctgaaga gccaccagcg ccacgtgcac agcagcgagc gccatttccc     1260

atgcgagctg tgcgggaaga agttcaagcg caagaaggac gtgaagcggc acgtgctgca     1320

ggtgcatgag ggcggcggcg agcggcaccg ctgcggccag tgcggcaagg gcctgagttc     1380

caagacagcg ctgcggctgc acgagcgcac acacacggga gaccggccct acggctgcac     1440

cgagtgcggc gccaggttct cgcagccgtc cgcgctcaag acgcacatga gaattcatac     1500

aggggaaaaa ccttttgtct gtgatgaatg tggtgcaaga ttcactcaga accacatgct     1560

gatttatcat aaaaggtgtc acacaggtga aagacctttt atgtgtgaaa catgtggcaa     1620

gagttttgct tctaaggagt acttaaaaca ccacaataga atccatactg gatccaaacc     1680

ctttaaatgt gaagtatgtt tcaggacttt tgcccagcgg aattcactgt accagcatat     1740

taaagtccac acaggggagc gtccctactg ctgtgaccag tgcggcaagc agttcaccca     1800

gctcaacgcc ctccagcgcc accgccgcat ccacacaggg gagaggccat tcatgtgcaa     1860

tgcgtgcgga cggacattca ccgacaagtc cactcttcgg cggcacacct caatacacga     1920

taagaatact ccatggaagt ctttccttgt cattgtagat ggctcgccca agaacgatga     1980

cggacacaag actgaacagc ctgacgaaga gtatgtgtca tccaagcttt cggataaatt     2040

gctgtctttt gcagaaaatg gccatttcca caacctggct gcagtccaag acactgtacc     2100

taccatgcag gagaacagtt ctgctgacac agcctgcaag gcagatgact ccgtggtgtc     2160

ccaggacacc ctcctggcca ccaccatcag tgagcttagc gagctgaccc cacagacaga     2220

ctcgatgccc acacagcttc actctttgag caacatggaa taagagcttc aagcagttcc     2280

catcctgtta gtctgcgtgt gtggtagctg aactcaagat gatgtggggc taagaaaaat     2340

aattgtccat gtgcaaagat gtgggcaaga atggcctctg cagattttcc tgaacttctg     2400

ctaacttgca cggctttatc acagcatttt taaagctttc cctcaaaaat cctgatctgc     2460

atgatctcag ctactttatt gacaaaaagg cagtgaacat aacctcactt aattctggtg     2520

tagggtgtat gtgctaatcg ttctaattct tgattaccta gtttatagat aactgctggt     2580

cttaattgca gagtacagag aactgaacca gctcctgata ttgtagttag cagtcttcct     2640

ggcttctcac tctgccttat atttccatgt gggtttactt ctctcataac tactttcaag     2700

gtatttttct tccaagctga aataaaactg gggccacata ttttcagtca tttcttccct     2760

gttgaattga agcaaatcag attttctgtg gggaccctca aatgcaactg aagaaataga     2820

ttgttgcatt cattcctccc caccccccat ttgtaggcag taaacaaagt atgactgaca     2880

gattgaacac ctgcaaaact gctagcgtaa tctcagcaca tacgcagcta ggaagtttgt     2940

cataaaatca acttagaaat gagatgaggc tgttcagttt gtcttaaaaa aatcagatta     3000

ggtaaaagct gtcctaccaa agagtctagc aaaacaatat agtatttttt tgcagaggca     3060

tgaaaaatta agacgcttta gagtacttga aagttgtgta gtcattttat ttgcaaaatg     3120

aggtgactgt ggcaaattat agaacacaga gtattattac ttttgccagg tttttctgac     3180

ttgatttctg taatttccag aaacccagac ttctcatttc cacacctaga gatggaaaca     3240

ggcaagtaac tgacatgtct atttccttgg gagcatgtga gaacatagca gtagggacca     3300

aaagtctcag cacacttacc tccgattatg ccttaaagag ttgattgtga agaaccagta     3360

actttgtccc aaatgcttct ttggctgttt catgcaggac ttaattattg cttttaaaaa     3420

ttcacaatga aaagacgatt ctgctgtatt tgttaaacgt tgacatttgg ttctagggcc     3480

ttgagtatgt gccacgtgct tgtgaaatgc tatgattcac atgtaacatt taaacattaa     3540

tttaaaaagg gaaccttgga gaattctttt gttcactagt tccttttttc tctacatttt     3600

taatttatta aacttgctgt gaaaacactt tgattttcta agaggaaggt actttaagtt     3660

ccagaatgaa catgtagctg cactatgcca gaaattaatg agggaagact ttcttcctaa     3720

gtgcttatgt tttaacttat gttagtgaaa ccactacaag gtgtttcagg cgctgataac     3780

atgcttcaca cctgcccttg gaggtcacag tactaattta cttcaaattt agttatgaca     3840

gtgtcactgt atcctagtta tgtttacagc acaaataaat aatgactgtc atacatccag     3900

aggagaccga acctgcccag ctgatgtact gttttatgga ataaagtcac ttgatcagaa     3960

ggaattgaaa caatagatca ttttgttacc tactggaggg atttttgtct tgaatttgtt     4020

tccttagaaa ttctacaaaa aaatgttgtt aataaatgtc tgctttgtaa aagcagtttt     4080

gcaatttttt aaagatctat ttctgttata atttaggttc tgcagaaata tgattcttaa     4140

ttgaaacata taatttgctt aattacgtga ataatgaaat gtaaaatccg ggtccataag     4200

cctttatttc atacagtcct aggattaagc tgtttaactg cttggatccc agttggtctc     4260

tggcagtggg atcctggaga ggagaaatcc tggcctctgc tcatgcgcag gccacaaccg     4320

ggctggaagt gcggttgagc tctctgccac tttcttcaat gtaaaaagta ggcatcaaag     4380

atacgacttc tactatatac atttctctgt ccctgagaac agagaaacgt aaccctgtag     4440

gggactggtt acagaggacc tcctggagca tctgccccat tcctccaagt ccaagcacag     4500

ccatgctgag tggaagcgag gccaccatct gagtggattg gtcccaagtg tgtaatgagg     4560

aaagtggcca ggtgccggca cagtgcctct cccagagcct caagaagggc catttaggag     4620

cttgcttcaa ccattttcca accattttct gtgaaatgct gtcagcccaa actccaaagg     4680

gatgtgcagc ctttcgtttt accaaattct ttgctgtcgt ttggaaaaaa tgggccatgt     4740

ggtggagacc tttatttaag gtgattttta cagaaatgtg attttgctgt aggtgattat     4800

ccaaacaagt aaatttgagt gtataattta atttttaacc tgttaaataa accttgtccc     4860

tccaaggagt tcatttttgg gaaaaaaaaa aaaaaaaaa                            4899


<210>  2053
<211>  9793
<212>  DNA
<213>  homo sapiens

<400>  2053
gctctcccca cctctccgcg ctgagcagcc acgtcggcgg cggtccctgg tccagggagg       60

ggcgtggcaa aggcccgtgc gcggtacgtg tcccgcccct cgctgcccgg agcccggatg      120

aagagtaacg ccattaccgc cggagccgcc gagagcctta gccgacggaa actggacact      180

ggaccggcag cgccatgaga ctcctccccc gcttgctgct gcttctctta ctcgtgttcc      240

ctgccactgt cttgttccga ggcggcccca gaggcttgtt agcagtggca caagatctta      300

cagaggatga agaaacagta gaagattcca taattgagga tgaagatgat gaagccgagg      360

tagaagaaga tgaacccaca gatttggtag aagataaaga ggaagaagat gtgtctggtg      420

aacctgaagc ttcaccgagt gcagatacaa ctatactgtt tgtaaaagga gaagattttc      480

cagcaaataa cattgtgaag ttcctggtag gctttaccaa caagggtaca gaagatttta      540

ttgttgaatc cttagatgcc tcattccgtt atcctcagga ctaccagttt tatatccaga      600

atttcacagc tcttcctctg aacactgtag tgccacccca gagacaggca acttttgagt      660

actctttcat tcctgcagag cccatgggcg gacgaccatt tggtttggtc atcaatctga      720

actacaaaga tttgaacggc aatgtattcc aagatgcagt cttcaatcaa acagttacag      780

ttattgaaag agaggatggg ttagatggag aaacaatctt tatgtatatg ttccttgctg      840

gtcttgggct tctggttatt gttggccttc atcaactcct agaatctaga aagcgtaaga      900

gacccataca gaaagtagaa atgggtacat caagtcagaa tgatgttgac atgagttgga      960

ttcctcagga aacattgaat caaatcaata aagcttcacc aagaaggttg cccaggaaac     1020

gggcacagaa gagatcagtg ggatctgatg agtaaatgtt cctttgtgca acaattcggt     1080

ctttacttaa cctgccctaa tatttttcgg cctgatggga attagtgcag agaagccatg     1140

tcaccataga aggcaactcc tacttgtgtg tggactgagc aatcagagtc tgtggcgata     1200

atattgctga aaatgcactg cattcatttt tctaaagtaa caaatttggt ttttttttaa     1260

accattaaaa tctatgtgtg tgcgtgtgta tgtatgtgag cagttggtct taccagaatc     1320

attgttgaac tacctgaaac aagtctttag aatactaaat ataatgctgt tgtctcttcc     1380

tttttgacat tttctgattt tttcccccaa aactcagtta atatttaccc actatgatta     1440

ttgatgtcct gccttgaaca gttttaaaga aaacaatttt tggaatagct caaatttcaa     1500

ttgatggcac aaatcagcat tttgttgttg ttactgtatt acaattagta ttctaaaggc     1560

agaagcagaa gtagctgctt tttagcaata gaattgtttc agtattttgc tgctgtttaa     1620

tgcgcatctt cagaaaactt cccagtggct tcaaggaatt tggggatctc tctggcaaca     1680

aattgtgaaa catgaaattt ctgctgactt taatatatga aacctaatcc tacccccttt     1740

tttaacaaaa agaaactagt acatttgtga aaattgtgtt gtgttgtcca ttgttgctct     1800

agttctgacc cagaggtagc tctggagtga ttttagacct actcactcag ttgtgtgtag     1860

gtttttttgt tttgttttga gagagaattt ttctctcctt aatagaagca tcctttttaa     1920

agagaagttg ccttggtcca cacactaagc agaaaaccaa gttatcagga cagagatatt     1980

tcccagttac tcctaatcaa tgaagaaagt gagttggata tttttaaagc agttaactaa     2040

ttttttctta cctaatcttt tgggagtttt gcttgttgat ataacctttt tagttaacct     2100

gaaagattcc aaaaattgtt cttaagtgct tgagactgga accaaaatta aattgtactt     2160

cataaaatcc tcttatagag ttactcttgc cctagattgt aaattaagtt tggcattatt     2220

gtcagactgg atggagggtg aagtaaaata gtatgaacaa ttaagaggct ctccccctct     2280

tgtctttaag ccatattctc ctacatgtat tttataagaa aatgttaagt caaattttag     2340

tggctcttta attcctgacc tcttcattct ccttttcagt ataacctccc ctatgctcat     2400

gcccacacag acaaaaaaac aaaacgaaat acacacagaa aaaagtcttt ccaaactgtt     2460

taagtattta aacatctgag ccaaagcaga tagaagttat tgtataattg ttaatcactt     2520

tgcaaatagg ggctatcaaa ttacctatat tggcattgct ggattataaa ctctatatct     2580

gtaatataaa gtgtttgagt ttttaattgg gctgttatga tcagtagttg attttgagaa     2640

agctctatga gctctaagta actgcatggt tttttgttta atgtaatata ggagaccctt     2700

cacattccca aggaatatat tccaaaacat ttttgtgaat atctaagttt gtgaaactac     2760

tagggcatga tacagtaagg tgtaattaca gaatttacga aatgtaaatg gcctctacag     2820

agttttatgg aatacctggt actaacgtag gcagctgcaa aaccacactg agttacagct     2880

gtcagccctc ctcattccta aataacttgc cttacatatc agccctccca cttctgaagt     2940

tcaaattagt gcctcggaaa tgtagaattt attatttgtc attttttttt ttttagcata     3000

gattgagaac agttgaactc ttaaatcctc agatgccagg ggtctgctct agcatcagta     3060

agtatttagc agaaactaac tccgtaatga atggaattca attccacaca tggtttgttc     3120

aagcacactt aataagtagc ctatttttta aatgtctttt taaaatgtaa atatttggat     3180

gaagtttttc tttgttttga tatattcatt tgctacacca actatgtttt cagaattcat     3240

cttttgaaca acttggtttc agaatatgta aaatgacttt aaggatcttg tgtatcaaac     3300

ctatccccgg atgtgtgaga ataatgtgtt cataaagcat ggatctcgct ttggttgtat     3360

agcttcctca tttacttcat ggtcttacat agctggtgac tttcagggct aatctgccct     3420

ctaaagcatt gtcccaggag aggaaaagga aatgggacct cagaagtaga agcctcaggg     3480

aaggagtaaa gtagaaatca gaagaaaaga agcttcactt gatagtaata aggtttttaa     3540

cttcaagtac cttcagaaaa tgtgattttg ataagaggaa agggcaaatt tagaccttaa     3600

aaaatatgga agaactactg ccttaaaagt gcatttgtgg cacatcagcc tagaactgta     3660

tcatggctgt gctggggaga agtaaatggt ggtaatgtaa cattgccacc tttacttaat     3720

gatgtgttat tttcgaggta cagtagatca atatagtaat aggcgagcct catatatagc     3780

attcatcttg tacaatgata tccataccct tgatatgaag gaaaattgac ttggtttgtg     3840

catttgaata ctgaaataat tttttaaaac tcagtgacac ataccatctc ttgccaagac     3900

tagaccctgt attttagttc ctaaattaga tgtttaaatt taaaaacatt ttcagatgta     3960

cttaagtact tccatagtac tttttttttt tttttttttt ttgccccctg agacggagtc     4020

tctgtgtcac ccaggctgga gtgcagtggt gcgatctcgg ctcactgcaa cttctgcctc     4080

ttgggttcaa gcagttctcc ctgtctcagc ctcctgagta gcttggatta caggcgcccg     4140

tcaccgcacc tgcctaattt ttgcattttt agtagagacg gggtttcgtc atttggccag     4200

gctggtcttg aactcctgac cacaggtgat acgcctgcct tggcctccca aagtgtgctg     4260

ggattacagg cgtgagccac tgtgcccggc ccactgttca ctttttgaat ggcatcattt     4320

tatagctgta gaactaaaat caatgtttgc cccaattttc ttaagtaaaa ctctactttg     4380

agctcttacc tccaacttag taaaaagcag cttcacacac aaacaagatt cttactggtg     4440

gaatgttagg tttcgttgtt aagttaatct gtctataagc tcatccttag aggatatttg     4500

aggaggaaga acaccttgca gctgacttgc aaacatctaa ataatttatt tcgggtgctt     4560

atgaatgtta ctaatggatt ttgtatgaat ttttatccct tttcatttat acaaaaacct     4620

gggcttttat gttaattata tcatctgagg ttctaaggtt ttttttttag attttgaaat     4680

ttagggataa tagctcttag gtttgggtac cactttgctg cagtttaaga aagggggaag     4740

ggaactcatt tattaaacat caatcacgtg ctgtgttctg tttgttttct agtcatcata     4800

tcacacacct ttacgacagc tcactgaagg aaggtgatac tgttcccatt ttgtagatgg     4860

aatagacaaa acctgaattt aagtagcttg ctcaaggttc catattgaat atggaaagtt     4920

caaatcatct cagtaatgaa tataccatat atacttgctg tattgtatct atgataattc     4980

agttacccac aatacccttt taaatttctg ttaatgacat acctttaaat gtctccttga     5040

tgaacagaat catggtcttt aaaaacattt tcatgggttg attgcatttt caagctctaa     5100

aggattgaaa gataaatctt cacgttaaag gtaagagtga agtatctgct cttgggttac     5160

agaaccagat agtactagaa ctaagattac agggtaaagc tgcttttatc ttttttcttt     5220

ttctttttct tttttttttt gacatggggt ctcactgtat tgcccaggct ggaatgcagt     5280

ggcatgatct cagctcacgg cagcctctgc ctcttgggct caagcgattc tcctgcttca     5340

gctttccaag tatttgggac cacaggcgca caccacaggc ctggctaatg tttttgtttt     5400

gtttttggta gagacggggt ttcaccatgt tgccaggctg gtctcgaact cctgagctca     5460

agtgattcac ccaccttggc ctcacaaagt gtcaggctta caggcgtgag ccactgcgcc     5520

cggctcacag ggtaaggctt ctgtctggtg tgttgtatta cggattttgc ttaataggca     5580

cagtgaggca ttaaaaagaa aattcagtat gcctgtagaa aggataatcc ttgtttaaag     5640

tctccaaatt gcagtcaaag atgttttgac tgtgcctttt tttgttcccc tgctgtccct     5700

tatgtagact tctgtcagta cccatggcag cctgtcatct tgttgacatc tccttctgga     5760

ctgtgagctc tgtatctggc ttgtttttca tccccagctt ctagttcaca attaggtaga     5820

accctattac tctttgaaga aggaacaaga aaatgtgggc cagttttcat ttgccattct     5880

tccatgtgag ttagtatggt tcgtaagtat tcctggtgat acgctagtat tggcaattct     5940

gtgaggttga acaaaggggt ggtatggtgt gctagcgtgg gaattaggag acctctgggt     6000

cttgacagtg ccctggccac taagcaaagg cagttcatcc ttggagtctc aatgtgcttt     6060

tttgttaatt gagatatgct tgaagtatca gccctaaata gtctgattct gtgacctaca     6120

aacccttact taattcagtg ttactataaa tgattcttcc cttaaaccta ctttttactt     6180

agcaaaagag aaaaaaaaaa aaaggaaacg ctcatgtcag gctgcctggg tttgaacccc     6240

agatcccctc ttagttggag gcaagttgta tgatgcttca gcttttggtt cctgcctcct     6300

aaggttgtta ggagttactg tgtgtagctg cttagaacat tgcctgggtc tcagtaagcc     6360

gcttaagtga ctgctctcat tttcgctgta aagcaccata ctgtaataac atcccatgaa     6420

gcatggggcg gggaagagta tatggtacct tatggacttt gatgtggtgg ggtagtaggt     6480

aaattctgaa tatgtaagct acatagtatt ctttttgtaa ctaaaggata aaagttttaa     6540

gatgggcatg taatatggct agcactggat tttaatgatg agccagagta ataaggctgg     6600

caaggggagt ttttgttttg taataaatct cttacacctg cacatccagt tctttttaaa     6660

aacacgtttg aagaggctcc atatttctca gtgaagctgt tggggttcat gttatttttg     6720

aaaatcatct tgcaatttat ttcagcatca gactgaacca cccaaagaaa attagtctat     6780

ttctgaacag ttttttcaga aaccatattg gtctgatcac ccaacattta tagaaatagg     6840

cgcttaaggc ctagaggcat ttcagaaagg agaatgagaa atactgtggt caagagtagt     6900

gttcagatgg agaacatcaa gcatctgctc tgcccttcca cacacatcct catttcatct     6960

tcacaactgc cctaggtaac cttgttatct gtaatgaaac agcctcaagg agcacagagg     7020

cactcactcc tcacgtttgg tctgttgcca tttccggctt ggttggaata gggtaggagc     7080

cttttggcag ggagcacatt ctcagtaatg cagagtgcac tcacctgggt tctagcttca     7140

acacttagga tttgcttgat attttgtatt ctctgaggca ctgcctgtat ttgtttctgc     7200

tatcacagtc cagagtcaag cttcatttat aaagactggg cagggcatgg tggctcactc     7260

ctgtaattcc agcactttgg gaggctgagg tgggtggatc actttaggtc aggagttcaa     7320

gaccagcctg gccaacatgg tgaaacccca tctctactaa aaaatacaaa aaggccgggc     7380

acggtggctc acacctgtaa tcccaacact ttgggaggcc aaggtgggca gaacacctga     7440

ggtcaggagt tcaagaccat cctggcgaac atagtgaaac ctcgcctcta ctaaaaatac     7500

aaaaattagc caggtgtggt ggtgcatgcc tgtaatccca gctacttggg aggctgaggc     7560

aggagaattg cttaaacctg ggaggtggag attgtggtga gctgagatcg tgccactgca     7620

ctccagcctg ggagatagaa cgagactcca tctcaaaaaa gaacaaaaac aattagccga     7680

gcgaggtggt gcacgcctgt aatcccagct actcatgagg ctgaggcagg agaatcactt     7740

gaacccagga ggaggaggtt gtagtgagtc aaggttgcac cactgcactc cagcctgggt     7800

gacagagtga gactgtctca aaaaataagt acataaataa taagtaaaag ctactaacaa     7860

ttaaaaaata aataaataaa gacaagactg tctggaaaat ggctctccta aaaggaccag     7920

ttgccatcat ccacagtgga agattcaaag cagttggtcc ttggtacgta tgagaagcgg     7980

atttcattcc cttgaattct acagagcagt ttattagagt gaatgcattt taaggccttg     8040

catttgatat gtcatccagt tcataatcaa gttgcctttt tctggctaaa acataatgat     8100

tatgtatttt tctcatttgg tcctacaagc tgctggccct ttgtccctcc actgtgggaa     8160

tcagatctag aggaggctga gcctgcagac acagcagtgg ccaaaaggtc actctaagtg     8220

ttttgtcttg actccttact tgaagtccac ccagctagca cacatctggt ttatactgaa     8280

gccccctgcc tagaaatact catttcagga accaccagta agcatctgtg accacacagg     8340

ctttttgact gatggcttcc cggatctggt ttcaagggat aaccccgtct gtgtgcatct     8400

atggtcttct ctctacagcg aggactttgc agtgctgctt gtggtccaca caaggggctc     8460

agagctgagt ctgaactgct tcatggtcac cagctcctgt cccttccagt cttgagaggc     8520

ttttttctcc agatggaacc tttccttccc gccgttttct cggtctctgg ctgtttttct     8580

cttgtgcccg tctaattgga cacctcctgg cttccatctc tgtggttctc ctgcctcact     8640

tcctgttctg ttgtttttcc gttttgtcaa aatatctcct atgttcttgg cttccttttc     8700

gtcgccaggt tttcagcttt cctttagctc ttcttctaat atggcttctg cccacaaaag     8760

cctgctctgt caggatctca tggttctcca cttgccagaa ccttcttcag cctcagttcc     8820

tcggcctcaa cttgtacgtt taacccattg accaccaccc cccaaattca ccttcatttc     8880

tttgaccctg ctcctcactc cttttctgtt gaggaatctg ttgactaact ccaggctcac     8940

tcaggctcac cgtcctgctc tctgcaccag cctttccaga gcgtgccagt tctcatggct     9000

tcatctgtta actgttgatc acttcagtcc tgatttttag acctaaatgg tttccttaac     9060

gccattctaa ctgcctgtga ctcattttca cttacagtgt ttattgtaac gccaaaccaa     9120

caaatcacag gtgcttgctt ctctccataa atctccccag tctaactttt tgtcattcaa     9180

catgactcgt ttatccaacc tgaaatcgca tatagcccca agtatggtgt tttgtacaca     9240

ggtatttaat aagtgacttc cagttttggc tctgctatga ataaaaagag atttcagttc     9300

tcttcacttt gaaatctaac aactcagaga acattgaaga aattggaatt tagttgggat     9360

gaaatacttg tggtttaaaa tatttctgtt catattttct aatttgttgc cggaggtctt     9420

gggttttcta tttgagtgct tgcaaactca atgtgatttc tgtcagcata tcttaggttt     9480

gtttgttatg aaacttatgc agtgtgaggt tctatctgaa aatgttattt agctatcttc     9540

tgggactatt taatgaaagt ggggtcatga atccttaaaa ttcttgtgca gctttgagaa     9600

acatttctgt tatttgggta tcagtttgta agtgtggtaa agccaagatg gaaacgagca     9660

ctttgctttc ttggttgttg ttactggtct aacctcctgc ttgaactagt ctgctgtcct     9720

gtcaaatgca tctttttatt tacatgtccc ttaaattaaa gctgatcatg aaagtaaaaa     9780

aaaaaaaaaa aaa                                                        9793


<210>  2054
<211>  3488
<212>  DNA
<213>  homo sapiens

<400>  2054
ctgcctcagg aagcttggct tcccctccca tggggaagtg ctggaatcca ctcttgcctg       60

accctcccat aagaaacaag ggaaattcct ttacgtgagc cgccttgctc agaacaaagc      120

ttggcgtgtt tcttattcct catcaatctg acaaaatggg tatttatttg tgcctctcaa      180

gcgtgtggct tggacatgat gttccgcatc gtggaagtgg ccgtgcacca agtggaatat      240

ctgttactat agtaacagtt cctttttatt gataccagaa taaacaggaa tgcaaaggct      300

gtctcacttg ttggcacatt tcagcagcct ccgttcccag gggtttaaga accgccctct      360

agaggcagcc ctccttgcta gtctgggact tcccggtgga gtgaggaacc cagcaacacg      420

ctcctgactt cccttcccaa ggactcgacc tgagaaggac acagcagtct ctgaatttca      480

tgctctcctc tttgatgtga agaaaatgaa aagctgaaca gttgtggaac tgtggataga      540

gttagacaat aaggccgcca tgtactcgga gatccagagg gagcgggcag acattggggg      600

cctgatggcc cggccagaat acagagagtg gaatccggag ctcatcaagc ccaagaagct      660

gctgaacccc gtgaaggcct ctcggagtca ccaggagctc caccgggagc tgctcatgaa      720

ccacagaagg ggccttggtg tggacagcaa gccagagctg cagcgtgtcc tagagcaccg      780

ccggcggaac cagctcatca agaagaagaa ggaggagctg gaagccaagc ggctgcagtg      840

cccctttgag caggagctgc tgagacggca gcagaggctg aaccagctgg aaaaaccacc      900

agagaaggaa gaggatcacg cccccgagtt tattaaagtc agggaaaacc tgcggagaat      960

tgccacactg accagcgaag agagagagct gtagggccag ctgccgggct caggccactg     1020

cccaccctgg cctggacagc ctccttcagc ccttctgtac ctggcagccc tgggccccag     1080

gccctgggac gtctgtgatg ttcccacctg cttctgtaga aatgtgtcac cccagagggc     1140

ctggctctcc ctgggaggct ggggccccta agctcctagg ttttccttcc aagcacccag     1200

ccctcctgct ccaagaggga taacctgcac ccctccctgc aaggggttca gagcccagca     1260

caggagcttt ctctggcaga attgaggagg aagaggtggc cctctgactt gacaagcctt     1320

ctgttctgcc caggccttcc caccaggaat ctccgaggct ccccagggcc ccgcttctcc     1380

gtacacccca gctcctaggt ctcagagaac tcccccacct gtggttttac ctgcagccag     1440

cagagcttag cttcaaggac acctgccttc aaagccactg aggggaggaa gggcagggca     1500

gactgcagat ggccttgttg ctggcatccc ggccaggtgg gcggggacta acaaagacag     1560

ctgtttaggg tcttctcccc tcacccatgc tttcatcatc ccctccgcac agcctccccg     1620

tccaggcctt ctaaccacac ctacccaggg ctgccgcatt cctgcactca gaagtctgca     1680

gcggtgcctc acaaacttga ttgtgcataa aaatcactgg ggatcttgtt aatacagctt     1740

ctaactcaat agatctggga gatcctgcat ttctaacaag ctcccaggta aggcggaggc     1800

tgctggtgtg aggaccatgc tgtgagcagc agggcgagag tgcccagggc tgatatatat     1860

tggaaatatc acccctgaag ccatcgctgg cccccacctc ctgtggactg atgccccagg     1920

gattcccacc ccacttctgc aaccccaggt atccttcatt atccacccca tcccagactc     1980

ccaccccagg gattgcccgt gaagactttg gcctagcaaa ttgtgttggt tatgtgagtg     2040

ttgttttaat cagagatgta catgattgcc aatctgcatt tcttaccagt gtgaccacac     2100

tgttacgatg caattctagc caaaaaaaaa aaaaaaaaaa aaaaaatttt ttttttttac     2160

tttttcctag tcttatggaa agcaaatata caatgatttt cagtaggctt ctggaataga     2220

aacagtggtt tgaagacccc actgccacct ttatggactg gcccctttga gtctgaatcc     2280

ccggcctctg tcacctgaga cccaacccct agctgggcca actccagtga attcacccat     2340

ttttcttctt cagaaggcct ttcctgtgtg agacccacat attttaacct tttgctccta     2400

tcccattttt aaagaattag agaataaacc aggcctgttt cttttcccct gaaatccctg     2460

cctctggctt cctaaaccca tcatctaagg tgacagagca gtgctggaat agcatctcct     2520

ttcactttcc caaaactgcc acagatagct gccactggca tgctctttga ttcctggaag     2580

caaacgtggg actgtcggag gaaagggatt gttctggtct tactcataac tgggtggttt     2640

gagggtgact gaagtcgtgc ttttcctgtg tgtgctgcca gcacagggct gtaaatgcag     2700

atattgcgcc tgtgtgcgtg tgtataagtc aagctccaag aggctcctga atgtgactgg     2760

cgtgctgaga atgtgtttac gctgtttaat gtctgccagg tgagggttac actgaagatg     2820

cacaatccct aaaataaaga tcaccacttc cccaaagaag cagccctcgg gtccatgtgt     2880

tgttcagaca tgtgaagaga agcaagacag agggtctcag atggacgagg gctctccaag     2940

ggaatgcctg gggattcacc cagtggtccc cagaggtgct ccatggaggc aacaagtcat     3000

tccatgaagc cccagaggta gaagggacct caagcaccac gccctccagg gcagccgtgc     3060

agacgacctt ggttcacttt tcaggggtcg tcccaactct gtatctccag ccactccaac     3120

tgtggaggct gtaaatccag attttcactg ttccagtctc ctttgcagct taggatggct     3180

atgtgatcag gtgtggccaa tgaaattgaa gaggaagtct acctgggctt ctgggaaagc     3240

ttttccaata aaagacacag gcatggctaa cacctccctg ggcctcttct tcctaccttg     3300

attgagggtg tgatgcctgg agccacagca gccactttgc taccatgaca aaaaggccaa     3360

gagaatcaca gagtcattga ccctatcatt atttcaccaa gccaatacca gccgccatcc     3420

ttctccagaa ttcttgtaaa taaaataaat ccctctttgt ttaaaccatt aaaaaaaaaa     3480

aaaaaaaa                                                              3488


<210>  2055
<211>  4144
<212>  DNA
<213>  homo sapiens

<400>  2055
gttggaggtg gagtagttca gaatcaactg acgcagccgg gaattgagct ttgcaaagcc       60

acttgcaagg aagggaagca tctgcccaac cctcccccac cgcgcgccct ggatcctctg      120

cctgccccct cccccgtgac gtcaccctag tcctgtcccg gggagcctgc aaagcctctc      180

agattcaaac tgctagacgc actgctgcca ccgccaccga attggaaacg cgcgcccagg      240

ctccgtcgtc gccttcgccc gccgaccggg ccagccggct ctccgacctc cctacagaat      300

cgcaccccag tccctccctg gcagctcggc ttccctcagc tccaactctt ctcttccgct      360

cctgcctcct gtcggatttt taatttctgc gcacccccag tcaaattaaa tcaaccaaca      420

aaaagcaggg catcccccct ggaagcagcg tcttatttta ccttgttctc ccacttcctg      480

aagatgctaa actcctggtg gactgcagag gagagggatt cagtcttctc ctgatgtcga      540

ttgcgatttc tgctgggagc tcaagacggg cgagctgccc gagatctctt cgagataccc      600

caggggagga ggagatgggc aggatttagt aggacaactc ggttactaat gacttggcgg      660

ctggctgcga ccccccggga aatcaggtac ctgagttgac accgaaggtg cctaaagatg      720

ctgagcggcg tttggttcct cagtgtgtta accgtggccg ggatcttaca gacagagagt      780

cgcaaaactg ccaaagacat ttgcaagatc cgctgtctgt gcgaagaaaa ggaaaacgta      840

ctgaatatca actgtgagaa caaaggattt acaacagtta gcctgctcca gcccccccag      900

tatcgaatct atcagctttt tctcaatgga aacctcttga caagactgta tccaaacgaa      960

tttgtcaatt actccaacgc ggtgactctt cacctaggta acaacgggtt acaggagatc     1020

cgaacggggg cattcagtgg cctgaaaact ctcaaaagac tgcatctcaa caacaacaag     1080

cttgagatat tgagggagga caccttccta ggcctggaga gcctggagta tctccaggcc     1140

gactacaatt acatcagtgc catcgaggct ggggcattca gcaaacttaa caagctcaaa     1200

gtgctcatcc tgaatgacaa ccttctgctt tcactgccca gcaatgtgtt ccgctttgtc     1260

ctgctgaccc acttagacct cagggggaat aggctaaaag taatgccttt tgctggcgtc     1320

cttgaacata ttggagggat catggagatt cagctggagg aaaatccatg gaattgcact     1380

tgtgacttac ttcctctcaa ggcctggcta gacaccataa ctgtttttgt gggagagatt     1440

gtctgtgaga ctccctttag gttgcatggg aaagacgtga cccagctgac caggcaagac     1500

ctctgtccca gaaaaagtgc cagtgattcc agtcagaggg gcagccatgc tgacacccac     1560

gtccaaaggc tgtcacctac aatgaatcct gctctcaacc caaccagggc tccgaaagcc     1620

agccggccgc ccaaaatgag aaatcgtcca actcctcgag tgactgtgtc aaaggacagg     1680

caaagttttg gacccatcat ggtgtaccag accaagtctc ctgtgcctct cacctgtccc     1740

agcagctgtg tctgcacctc tcagagctca gacaatggtc tgaatgtaaa ctgccaagaa     1800

aggaagttca ctaatatctc tgacctgcag cccaaaccga ccagtccaaa gaaactctac     1860

ctaacaggga actatcttca aactgtctat aagaatgacc tcttagaata cagttctttg     1920

gacttactgc acttaggaaa caacaggatt gcagtcattc aggaaggtgc ctttacaaac     1980

ctgaccagtt tacgcagact ttatctgaat ggcaattacc ttgaagtgct gtacccttct     2040

atgtttgatg gactgcagag cttgcaatat ctctatttag agtataatgt cattaaggaa     2100

attaagcctc tgacctttga tgctttgatt aacctacagc tactgtttct gaacaacaac     2160

cttcttcggt ccttacctga taatatattt ggggggacgg ccctaaccag gctgaatctg     2220

agaaacaacc atttttctca cctgcccgtg aaaggggttc tggatcagct cccggctttc     2280

atccagatag atctgcagga gaacccctgg gactgtacct gtgacatcat ggggctgaaa     2340

gactggacag aacatgccaa ttcccctgtc atcattaatg aggtgacttg cgaatctcct     2400

gctaagcatg caggggagat actaaaattt ctggggaggg aggctatctg tccagacagc     2460

ccaaacttgt cagatggaac cgtcttgtca atgaatcaca atacagacac acctcggtcg     2520

cttagtgtgt ctcctagttc ctatcctgaa ctacacactg aagttccact gtctgtctta     2580

attctgggat tgcttgttgt tttcatctta tctgtctgtt ttggggctgg tttattcgtc     2640

tttgtcttga aacgccgaaa gggagtgccg agcgttccca ggaataccaa caacttagac     2700

gtaagctcct ttcaattaca gtatgggtct tacaacactg agactcacga taaaacagac     2760

ggccatgtct acaactatat ccccccacct gtgggtcaga tgtgccaaaa ccccatctac     2820

atgcagaagg aaggagaccc agtagcctat taccgaaacc tgcaagagtt cagctatagc     2880

aacctggagg agaaaaaaga agagccagcc acacctgctt acacaataag tgccactgag     2940

ctgctagaaa agcaggccac accaagagag cctgagctgc tgtatcaaaa tattgctgag     3000

cgagtcaagg aacttcccag cgcaggccta gtccactata acttttgtac cttacctaaa     3060

aggcagtttg ccccttccta tgaatctcga cgccaaaacc aagacagaat caataaaacc     3120

gttttatatg gaactcccag gaaatgcttt gtggggcagt caaaacccaa ccacccttta     3180

ctgcaagcta agccgcaatc agaaccggac tacctcgaag ttctggaaaa acaaactgca     3240

atcagtcagc tgtgaaggga aatcatttac aaccctaagg catcagagga tgctgctccg     3300

aactgttgga aacaaggaca ttagcttttg tgtttgtttt tgttctccct ttcccagtgt     3360

taatggggga ctttgaaaat gtttgggaga taggatgaag tcatgatttt gcttttgcaa     3420

gttttccttt aaattatttc tctctcgctc tcctcccctc cttttttttt tttttttttt     3480

tttctttttc ccttctcttc ttaggaacca tcagtggaca tgaatgtttc tacaatgcat     3540

ttcttcatag attttgttta tggttttgtt tcttttttct tctttgtttt tcagtgtggg     3600

agtgggaaga ggagattata gtgactgaag aaagaatagg caaacttttc aaatgaaaat     3660

ggatatttag tgtattttgt agaagatctc caaagatctt ttgtgactac aacttctttt     3720

gtaaataatg atatatggta tttccatcgt cagttaccga gtatagccac tgggtatcac     3780

tactttgtgt taaagtgcct tcgcacttta agtacattac ttaaatgttg cttttagctt     3840

tgataaattg aaaatatttt aatgtgttgt atttttgaaa ttgaaaacac tgtaaaatag     3900

attgatgtgt cagctatatt aagtcaacgt acagtttgct tgagttatag aaaccagcct     3960

gtcatcaaat gattctagtt ctaggacttt gtaggcttaa ctataaaata tttcctttcc     4020

tctgggttta agtgatttta tttaagtcaa ctaaggggat ttaacagtgg actagaggta     4080

ataagccacc tcagtcagga ttaataattc attaataaaa tatatttaac ccaaaaaaaa     4140

aaaa                                                                  4144


<210>  2056
<211>  6234
<212>  DNA
<213>  homo sapiens

<400>  2056
agttcagaga gaggagaggg agaaggagag aggggcagag gggaagggag agagggagag       60

cacgcgagac ggaaaggagc gcctcagagt ctctgaagca cgcaagagat aaccgattag      120

gaatttttcg ggcaactgtc acccggatag ctgtcagaga atcatcatca ccgcaactct      180

gacgtttcct acaagaagtt agagacttaa gcagtattgg catcggatgg aaatggtatg      240

catgctgctg tggaaaatat ccctgagctg aagaagtgca actatgtgtt gtgtgtgcta      300

aatgcccaga agaacccaga cccagtgggt aagagagacg aaatgtggag agaatgacta      360

acgacaaatc cgtgaatttg ttctctggag ttgctaattt gccagcccga agcaacacat      420

tttacaagga ggaaacattt tgctgcttct gatttctccc caaactggtg ctaccagatg      480

catggctttc tatgtgttgg aacaaatcat tcctaactgc agcatactgg gaaaggggaa      540

aggttgaggc aactaaccgg ctgtctccaa ataagtgatg agatataatg catcctccag      600

tccatgcacg cttcctcttg caatttgtgc atcattcctc agtggaaacc tttaaaccct      660

aaaatccagg aaaagaaaat aaatacatta tcatggacct gagggatttt tacctgttgg      720

ctgctctgat tgcctgttta aggctggatt ccgcaatagc tcaagaactt atttacacta      780

ttagagagga attgcctgaa aatgtgccca taggaaacat accaaaggat ctgaacattt      840

ctcacatcaa tgctgccaca gggaccagcg ccagccttgt ctacagactg gtttctaaag      900

ctggggatgc ccctttggtg aaagtttcca gcagcactgg ggaaattttc acaacctcca      960

acagaataga cagagaaaaa ctctgtgctg gcgcctcata tgctgaggag aatgagtgtt     1020

tctttgaact tgaggtggtg atcctcccca atgatttctt caggctgatc aaaataaaaa     1080

taattgtcaa ggataccaat gataatgccc ccatgtttcc atctcctgtc atcaatattt     1140

ccattccaga aaacactttg atcaacagcc gctttccaat tccatcagca acagatcctg     1200

acacaggctt caatggtgta cagcattatg aattgttaaa tgggcagagt gtttttggac     1260

tggatatcgt ggaaactcca gagggagaga agtggccaca actgattgtt cagcaaaact     1320

tggatagaga acagaaagat acctatgtga tgaaaatcaa agtagaggat ggaggcactc     1380

cacagaaatc cagtacggcc atactgcagg tcacagtaag tgatgtaaat gacaacaggc     1440

cagtgtttaa agagggtcaa gtggaggtgc atattccaga gaatgctccc gtaggtacct     1500

ctgtaattca gctccatgcc actgatgcag atataggcag taatgctgaa atccggtaca     1560

tttttggtgc ccaggtcgcc cctgcaacca aaagactctt tgctttaaat aatactactg     1620

ggctgattac agttcagagg tccttagata gagaggagac agccattcac aaagtgacag     1680

tgctggctag tgacggcagc tccactcctg ctcgagcaac ggttaccatc aatgtcaccg     1740

atgtaaatga taaccctcct aatatagacc tcaggtacat tataagtccc atcaatggca     1800

ccgtgtattt atctgagaaa gatcctgtca atacaaagat tgccctaatt acagtttcag     1860

ataaggacac agatgtgaat ggcaaagtga tctgttttat tgaaagagag gtcccatttc     1920

atttgaaggc ggtatatgac aaccaatatt tgttagagac ctcttctttg ttggactatg     1980

agggcaccaa agaattcagc tttaaaattg ttgcctctga ttctgggaag cccagtttaa     2040

atcagactgc cctggtaagg gttaagcttg aggatgaaaa tgacaaccca ccaattttca     2100

accagcctgt aattgagctg tcagtttctg aaaacaaccg acgtgggtta tacttaacaa     2160

ctattagtgc cacagatgaa gacagtggga aaaatgcaga cattgtttat cagcttggac     2220

cgaatgcctc cttctttgat ctggaccgaa aaacaggagt tttgacagcc tccagagtat     2280

ttgacagaga agaacaagaa cgattcattt ttacagtaac tgccagggac aatgggaccc     2340

ctcccctcca aagccaagcg gctgtgattg ttactgttct ggatgagaat gacaatagcc     2400

ccaagtttac tcataatcat tttcaatttt ttgtgtctga gaatctgcca aagtatagta     2460

ctgtgggggt aatcacagtg acagatgcag atgctggaga gaataaagct gtgactcttt     2520

ccattctaaa tgacaatgat aattttgtgt tggatcccta ttctggagtc ataaagtcaa     2580

atgtctcatt tgatagagag cagcagagtt cctacacttt tgatgtcaaa gccactgatg     2640

gaggacaacc acctcgttcc tctactgcaa aagtaactat caacgtcatg gatgtcaatg     2700

acaacagccc agttgtcatt tctccaccgt ctaatacttc ctttaagttg gtgcccctct     2760

cagccattcc tggctccgtg gtagcagaag tttttgcagt ggatgttgac actggaatga     2820

acgctgaact aaagtatact atagtgagtg gaaacaataa aggcttattc cggattgatc     2880

cagtaacagg taacattact ctggaagaaa aaccagcacc tactgatgtg ggattgcatc     2940

gtttggtggt caacataagt gacctggggt accctaagtc tttgcacacg cttgtgcttg     3000

tattccttta tgttaacgac actgctggaa atgcctccta tatctatgac ttgatccgca     3060

ggactatgga gaccccgttg gacaggaaca taggggatag tagccaaccc tatcaaaatg     3120

aggactatct aaccatcatg attgccatca tcgccggtgc catggtggtc attgttgtga     3180

tcttcgtcac cgttctggtg cgctgtcgcc atgcatcaag gttcaaagca gctcagagga     3240

gcaagcaagg tgccgaatgg atgtccccaa accaggagaa caagcaaaac aagaaaaaga     3300

aaagaaagaa aaggaagtct cccaaaagct ctcttttgaa ctttgttact atcgaagagt     3360

ccaaacccga tgatgcagtt catgaaccta tcaatgggac aataagcctg ccggctgaac     3420

tggaggagca aagtatagga agatttgact ggggcccggc acctccaaca acattcaagc     3480

ctaacagtcc tgacctggcc aagcactaca aatctgcttc tccacagcct gcttttcatc     3540

tcaaaccaga cactccagtt tccgtgaaaa agcaccacgt gattcaggaa ctccctttgg     3600

acaacacctt tgttgggggt tgtgacaccc tttctaaacg ctcttccact agttcagatc     3660

acttcagtgc ctcagagtgc agttcccaag gaggcttcaa gacaaagggc cccttacaca     3720

ccagacagtg taactcacac agcaaaagtg acaatattcc tgtcactcct cagaaatgtc     3780

ccagctccac gggtttccac attcaggaga atgaagaaag ccattacgag tcgcagcgcc     3840

gtgttacgtt tcatctccct gatggctccc aggaaagctg cagtgacagt ggtctaggag     3900

accatgagcc ggtgggtagt ggaaccctga tctcacaccc tcttcctctg gttcagccac     3960

aggacgaatt ctatgaccag gcctctccgg acaagaggac tgaagcagat ggcaactctg     4020

atcccaactc tgatgggcct ttgggtcccc gaggattagc tgaagctaca gagatgtgca     4080

ctcaagagtg cttggttttg ggtcactctg ataattgctg gatgcctcct ggcttgggtc     4140

catatcaaca ccccaaatct cctctctcaa cctttgcacc ccagaaagaa tgggtgaaga     4200

aggacaagct tgtgaatggg cacaccctga ccagagcctg gaaagaagac agcaacagga     4260

accagttcaa tgaccgtaag cagtatggct ccaatgaagg ccatttcaac aatggcagcc     4320

acatgacaga cattcctctg gcaaatctga agtcttataa gcaagcagga ggtgctactg     4380

agagtcctaa ggagcaccaa ctctaagaaa aggctatatg ggacctaata actttaaata     4440

gacatgctaa taccgtgtgc gtcagagctt tatgtattca atagatctct acaactatgc     4500

cccttctagc agggatacct ataactttgt gttagcacca tggagaatac aatgtttttg     4560

caacatatga gagaagatag ttctagccat gcaattttgt ttactagaat tgattacact     4620

ctccagagat ctctccattg tgcaaatttt ttttattatt gcattttatt ttgaccctgg     4680

actgctgcta tgaacaatag aatatgcatt tggaaagtaa gaaagtttca tggattagag     4740

tgactgaaaa acatatccag ttagaaaatt gtgctttttt tttttttttt tttttttttt     4800

gtcattgatt tgtgctggga ctgctatact tgacattata ctgcaaacaa aacttaaaga     4860

gataagcatt aaacctattg tgctgttaac aacgttagtg gacacttgta agtcaatcag     4920

tgttaaagta tttgtaaata gaagcaagct attattaaca acttttgtgt acttataatg     4980

ttcacctaaa aatgttgtag cataattctg tgttttatgg ttgcttctgt ccttcttttt     5040

atttacctct ttgttgttat ttttgttgtt tctttcagtg aggtgtttct gtgttagtag     5100

tctgtcttga cacacattgt tcaaacaatc tcaagcactt gtgtttaaaa aaggttctga     5160

aatcttgctt ctcatatgat agcttatgat gccggaattc tgtaaacaat aaagatgaaa     5220

gaaaaaatga aaactttata caaaaaagga cttctgcaaa agcttggaaa ttcagaacct     5280

attttttatc atcttatttt caaagtaggc aaaagcaaaa tcacttaatt agtaccatta     5340

agtgagagag taatggaaaa ctgttatcca tcaaaagtga tataatatcc tgtacttgtc     5400

actcatgtaa aactaatgta tcaaaattag catatatgga agaaaaatca ctattcaaaa     5460

atagtttcaa ttgggcaaat gtgtgtctac aactttgttg aaatggcaga gtctgtgttg     5520

atcctcatat acaataatgt tgttgtaaca caagtgttat tagaccatag ccacaaaata     5580

tttaatgtgt tgtgccttca tgatgtaaca gaacattctc caggtagggt agttggggga     5640

aataaaggga taaatctcta attattgctg tttaactgtt tgttatcata gttggtcaat     5700

gcctggcagg taccagcata ttgtcactta ggtcaaacca ataaagtgac aactaatgtt     5760

aataagatct cagttgcacg tgcaaacaaa tccaaattcg aacattctta ggaggttttt     5820

gttaaggcat gacagatgat ttaaacaaat aaatagcatg caacaaaatg tctttattga     5880

aagaagtgga agttatctta atgccacggt tcaccatcaa tttaaaagta aaaaaaacaa     5940

aaaaaaaaca aaaaatttaa aaaaaaggtt tgctaatctg atagttaatt tgttcttacc     6000

aaaaaataaa attactttgt aaatagcagt tcacattttt ccacagtata atggaaaata     6060

atgggtaggg gtgcattgct tattgaagta catttttgtc ggtttgtgag gggtgtttga     6120

tgactttgac agaataaata tctaaacaat tatccttgtt actgctttgc cagttctacg     6180

ttatttacaa ttattcagct cttgcaataa atgttctgaa ttcctgaaaa aaaa           6234


<210>  2057
<211>  9573
<212>  DNA
<213>  homo sapiens

<400>  2057
ggcgaccgcg gcggcgctct agctgcggca tgtctgcgtc tctactgctc tgggaggagg       60

aagagaagga ggaagaggag gaggaggagg agggggagga agaggagaaa ggcgcagggg      120

tgggagctgt tgccgaagct gccacagcaa aagttctccc ccctcccccc ttcccctcct      180

ctcaaggccc ctagaaaggt tggagctgcc gccgcctgca gtcggtgacc gcgcgactcg      240

gcgcccgccc gcggatagag ggaggaatca gcagcttgga aattcaagca cgtgatctgg      300

cgggatgggc gtttgcctaa cgtatttaat ggaggaatcg gatggcataa gtgattaagg      360

tggtattgag gatttctgaa gcctatgaaa ggtagaaact caaccatgat ttctttttca      420

actctacagc attcctttcc ttgaagtctt cgtttttacc ttagtctcgg gcagttatac      480

ttaagcatga acattgacga caaactggaa ggattgtttc ttaaatgtgg cggcatagac      540

gaaatgcagt cttccaggac aatggttgta atgggtggag tgtctggcca gtctactgtg      600

tctggagagc tacaggattc agtacttcaa gatcgaagta tgcctcacca ggagatcctt      660

gctgcagatg aagtgttaca agaaagtgaa atgagacaac aggatatgat atcacatgat      720

gaactcatgg tccatgagga gacagtgaaa aatgatgaag agcagatgga aacacatgaa      780

agacttcctc aaggactaca gtatgcactt aatgtcccta taagcgtaaa gcaggaaatt      840

acttttactg atgtatctga gcaactgatg agagacaaaa aacaaatcag agagccagta      900

gacttacaga aaaagaagaa gcggaaacaa cgttctcccg caaaaatcct tacaataaat      960

gaggatggat cacttggttt gaaaacccct aaatctcacg tttgtgagca ctgcaatgct     1020

gcctttagaa cgaactatca cttacagaga catgtcttca ttcatacagg tgaaaaacca     1080

tttcaatgta gtcaatgtga catgcgtttc atacagaagt acctgcttca gagacatgag     1140

aagattcata ctggtgaaaa accatttcgc tgtgatgaat gtggtatgag attcatacaa     1200

aaatatcata tggaaaggca taagagaact catagtggag aaaaacctta ccagtgtgaa     1260

tactgtttac agtatttttc cagaacagat cgtgtattga aacataaacg tatgtgccat     1320

gaaaatcatg acaaaaaact aaatagatgt gccatcaaag gtggccttct gacatctgag     1380

gaagattctg gcttttctac atcaccaaaa gacaactcac tgccaaaaaa gaaaaggcag     1440

aaaacggaga aaaaatcatc tggaatggac aaagagagtg ctttggacaa atctgacctg     1500

aaaaaagaca aaaatgatta cttgcctctt tattcttcaa gtactaaagt aaaagatgag     1560

tatatggttg cagaatatgc tgttgaaatg ccacattcgt cagttggggg ctcgcattta     1620

gaagatgcgt caggagaaat acacccacct aagttagttc tcaaaaaaat taatagtaag     1680

agaagtctga aacagccact ggagcaaaat caaacaattt cacctttatc cacatatgaa     1740

gagagcaaag tttcaaagta tgcttttgaa cttgtggata aacaggcttt actggactca     1800

gaaggcaatg ctgacattga tcaggttgat aatttgcagg aggggcccag taaacctgtg     1860

catagtagta ctaattatga tgatgccatg cagtttttga agaagaagcg gtatcttcaa     1920

gcagcaagta acaacagcag ggaatatgcg ctgaatgtgg gtaccatagc ttctcagcct     1980

tctgtaacac aagcagctgt ggcaagtgtc attgatgaaa gtaccacggc atccatatta     2040

gagtcacagg cactgaatgt ggagattaag agtaatcatg acaaaaatgt tattccagat     2100

gaggtactgc agactctgtt ggatcattat tcccacaaag ctaatggaca gcatgagata     2160

tccttcagtg ttgcagatac tgaagtgact tctagcatat caataaattc ttcagaagta     2220

ccagaggtca ccccgtcaga gaatgttgga tcaagctccc aagcatcctc atcagataaa     2280

gccaacatgt tgcaggaata ctccaagttt ctgcagcagg ctttggacag aactagccaa     2340

aatgatgcct atttgaatag cccgagcctt aactttgtga ctgataacca gaccctccca     2400

aatcagccag cattctcttc catagacaag caggtctatg ccaccatgcc catcaatagc     2460

tttcgatcag gaatgaattc tccactaaga acaactccag ataagtccca ctttggacta     2520

atagttggtg attcacagca ctcatttccc ttttcaggtg atgagacaaa ccatgcttct     2580

gccacatcaa cacaggactt tctggatcaa gtgacttctc agaagaaagc tgaggcccag     2640

cctgtccacc aagcttacca aatgagctcc tttgaacagc ccttccgtgc tccctatcat     2700

ggatcaagag ctggaatagc tactcaattt agcactgcca atggacaggt gaaccttcgg     2760

ggaccaggga caagtgctga attttcagaa tttcccttgg tgaatgtaaa tgataataga     2820

gctgggatga catcttcacc tgatgccaca actggccaga cttttggcta aaaaaaaaaa     2880

aaaagtgtaa ataatactgg cactttagaa cagattaatc aagagtgggg ttactctgtg     2940

taaatggagt gctgtacaga tttaagagca atgcgtaata acaagttaag ctgatatgaa     3000

tagcaagata atccaataac tgcatttcgt ttggttagtc agcattcttt gaactgcctt     3060

acatgttgtc acctttatag aagcaatgca ttacttgttt tagatcagaa acttgctatt     3120

ccacccacac caagttaaaa aggaaaaaaa aaagactttc gcacaattgt ttcctaactg     3180

ataacattgt acattcttag gagattagta attgtgtgaa atttactcat actgtttcta     3240

agtttttcag catagtcatt gcacttcagc agggaatctg agtatacttt acagacagag     3300

tgaacttaaa agtttaatgt caagagatta tggcttaaat aaattagtgt gtcctatagg     3360

gggaaaaaaa ccaagaaacc accttttaaa aagaatgata tgccatatac ccttgatttt     3420

cattttgcat tatattgacg tgtttttttg aaggaaaaaa agtaataaaa atctgatagt     3480

ctaagactcc actatttaaa agcctaatta ctttaaaaat atgcatactt tcagaacttt     3540

taccaaaaca cacaactgtt gaagcagtca cttctctatg gaagtatgca tattggtgtc     3600

agtttctttg tacagttgta cttagatatt ttttatgatt tttcatgtgc aggtatcaag     3660

gttttgaagt tttagtaaaa gaaattctgt agattacatt cccaagaaca taatgcttac     3720

acaaaatgta tattccacgt tttaaagctt aattgtattt tactttacat atacacttca     3780

gttaacatag agcacttaga atctatttgg tatttttgat ttctcaaagt aaaaaaaaaa     3840

ttagattttt aggtttgata tggttgtgtc ataatcatct cgtaattgac aattttaact     3900

tttggcaata aaaggaaatt gggatatctt tggaactgta aaacctggtt taatcttttt     3960

ctttctagac tcttgataga ttggataatt aaacagtatc cagagaaact aaagaaatgg     4020

gcattttaat tgcatatttt atcttgagtt actttttaat gaacactgct cattacaact     4080

ttacaaacca aaagtgttta ctaattccag taactaccat ttctttttca gctagatgag     4140

tgatcggaaa atttttgttg catttcaaaa tctaaataaa ctacagactt tatccttata     4200

ccatgaatgt ttttttttaa tactctgtct taaaataata cagcatggta caataaatag     4260

tgcttttatg tatatataca cacacacact tttctgaaga atgatggttt gagttatgcg     4320

ttgggcagtt ttgatttttg gaagttatat tagttattga ctctttgtta caactttttc     4380

atttttacat tttaaatttt ctgccatcgt tgtcacaatg cacatcctga tatagcacca     4440

gtgaaaatct aaaattaata cccttggaaa atgaaaatat tcttaatttc cattttgact     4500

cttatactgg ccctatagct ctgcagtctt tgtttcaata tagaatatgt tatccattta     4560

aattattttt tcttttattt aatgttatcc caagactgtt ctcataaaga aagggaagaa     4620

ataactatcc acccttaaca tccttcattt attttgaata tattggtgtt tttatgataa     4680

ggaatataaa ttatatttaa tgtggtttcc tgtatacttt ggttattaag ttttgcttga     4740

aatagtagtt ttcccgtttg acagctttct ttgctgccaa agttttcaag aatttaagac     4800

ttctttgaag taaatattta agttctgcca ttattgactc ttaagattgt gtgtgttgtg     4860

ttgtgcatta cataattaca aaaaggcttc attcaggtga tacgttaaaa atggaactgt     4920

gctcacccta aataggcatt ggtatttttc tcttttggtg agagtaggca tttatttctt     4980

gagttgtttt ggagcctgat caaaaatttt gttcatggag aacttgatgc aattttgata     5040

cagtggagag gtttttttcg gttgttttaa catcaccagc atagttttta gaatgtgact     5100

cttgctgagc atttagggtg agcttgggaa ggaaggcctt tgaaaatggt agttatgcaa     5160

gcagactttc aggtgttgca ttcctgtttt caacacattt ctttaaatct acataatggc     5220

agacttttct accaggttat aagcagtttt tagataagtg atactcagcc agcataactt     5280

attgacttac catttacgta tagtcatcac tctcttactg tgaaattcca aatgcctacc     5340

agagttacct tgttctatca taatatgaca aacatctcaa cagttttgga tttccccact     5400

ttggttcaga aggttattta atttctatct gggcattaat ggagaaaata agtagccttg     5460

tgtgctgctt cagattgaaa catggaggat atgagatatt cttctgcaat tcatgtttct     5520

catttctcaa agtgagcaca ttgttctata aaaacatgct ggtacaccct taaacttttg     5580

atcaatctga gtgaggtgtg cttttcctct tgggacctac tcacgtttga agattggaaa     5640

catcacgtta ggcgaggcag tatctcttga acatcttcta aagggttttt taaaacctta     5700

ttctcacata tttcatttgt cttgaatatt taagtggctc ttaaacgttt tgggtctaca     5760

tgcaaatgtg gtacttaaca aggtaggaat ccatcttctt agctctggct gagggtgcca     5820

gccatcggtc aggtcatttt tatctcaaga ggcagaaggc agttatgtca agaattgtgc     5880

tcagggcagg atttcgtttc cacagaggag agacacttgc agagtgccag ctaggttaga     5940

tcttttgccg cttctttcat ttgattaatt tgggttttta aagggctgtt taaaaaaaaa     6000

aaaaaaaggc cgggaaactt taaaagtagg cattactgta gtactgcatt tcttagaaca     6060

ttttaaacta gaactcattt ttttttcaca gtatatttac ttgaagaagc actataataa     6120

tcattgagaa gtattttgag tctgaaattt aatttaattt tccgtttcaa attgctttat     6180

ttcagggaaa taattttcca gttgttttgc tatattctgc aaataaaaac cgtgtttcct     6240

tttttcactt aaactttggt aggaaacaaa ctaaagcaga caaacatttc ttgttatgtt     6300

tgttgctttc tttaatccaa tggataaaaa agtaaaaccc tgtaaacatt attttatttt     6360

tttatgcaat accatgctgt aaatatggtt catcaaataa ggatgtacct atgattgaat     6420

ctttaattct gcacagttag agtttatata taaacgtgtc ttgacaatca aggactttta     6480

tgtgagtctt cctttatgat gtttattaat gttatgcatt ccatttgttt tgaagtgagt     6540

accaatgtgc taatttgtat tgtctgaaag tatgtaatgt ttttacagct tgtttttaag     6600

aatctgtaaa tatgtacaaa caaatcacag tactgcttta tgttagaagg catatgatgt     6660

tgtactgtat gtaagcaata atacatagca gtgctaactt tacaagtagc atcaggaaag     6720

ttctaaaaac atttcagagt tattaattat ccttatttca tttaataatg attatcttta     6780

atcagttttt ataagcaaat tccattgttc ctcctattgg aacgtaacac tgtttacaca     6840

gcataattga agttgcaggg gagacaggct aaatctgact tcatctgtac tcactttcac     6900

taagcattga atggccttac cactcttctg caagatggag gaagaccgca aaacttagtg     6960

cccatcacac tgaaggaagg gatgtggttt tttttcctgc ttctgtactg ctacctaact     7020

ttgtgatttg ctttggattt taatatttgt ttctgtttta gattcaagcc cgtaagtttt     7080

gaggtgactt cagctccatt gtgaaataga tagttctctt catatttcat aactacattt     7140

caataattct aaactttcta cattgatttt tagatactta tttttcaagc ttggtttctc     7200

agctgatcag atgaatttat tcaacttcaa tacaaagaaa gacaaaccta ttatagtttc     7260

aagtgagtag atattatact gtacaggaca gctatttgaa cacacacatc actgctttag     7320

aaataaaacc gccaatttat aaatgtatat gacctacatt ttataggaaa aaatgttttt     7380

aaatgctagt catttatata atgtgctttg aaggatttgc tagtccactt ctgtcacttt     7440

ttagtacact ggtatctttt atatgtaatg tatgcttttt attattgtag caaagcattt     7500

cagtagaaag aattttgcaa caatatgggg gaaatttttc attgttggat ttgaattata     7560

ctggatttta tctgtgtagt cttacttgtc tttattttaa tgctgtctga agggaacttg     7620

gtatccaaat aaagcaggta acctcatttt acttcaaggg catactgtgt agtgctgaat     7680

ttaatctgaa aatctgatga ttttgaaaag aaaaacaagt ttataaacat tgtacagaag     7740

aaattaaatg tgtgtgatgg aaatcctgat ggtggagcac gttgaatttt ctgatatata     7800

gtgttatttt cctgggatcc cctatgcctt ctttgtattt caactaataa aggaaaaacc     7860

ctgtcattaa aactggtaag ataataggat attctgatta tacagtatta ctattcctat     7920

cccattttct gaccttttct caatcactgt aaatttttat tttctatttc ctattgataa     7980

ttaaatatgt acataatata gacactgttg tatagaacta aatgaattgg gttgctatgc     8040

ttgagtgggt agtgaaatgg aaatatttga tgaatactga gagttcctaa aatgctagag     8100

caaatttccg agggaaaggg gggcatcgtg tgtcttggga aggttgcagc aggttgtttc     8160

ttcaactccc taagaaatca ttgggaagga ctcaactgca aactcgggat cagatacaaa     8220

atgggtcttt ccttcccctc tcccccaaaa aataggagca ctaaatttta aaatctactc     8280

aggtgacagt tgctttgcaa tgaaacttat cacattgaaa ttttcagtgt taaataaaaa     8340

gagatttgtg atatttttaa atataaactt ttacatcagt agtcagcagc ctgacaattg     8400

aaatttggta agtcgatata ttttaaaata ttttgctctc caaatagaat tgtttttaaa     8460

caattgggag gttttttgtt tctttaaata tgttttaatt gtcattgtaa aaacaaaatc     8520

ttgcttgacc ctatattatg ccatgaatga attgctgagc ctttataata cagtgacagc     8580

ttgtttcatg catagtcatg gaacatagag atgttcttta aactgaccta ttgataagag     8640

gtttaatgag tttcacggct ttcaacacta ttgtcatata gttatctttg ccatttggag     8700

tttataaaac cattttatgt attgtgatac taaaggaagt tgttttgctt tactttaaat     8760

tgaattatta gactaatatt tgcaaattct gcattttaaa tgtggacact ggctgtttga     8820

aaaataaaat atagaataca gttttatgga taattttcga gctgaatttt tcacaatatt     8880

ctgaaccaaa taacgaatgg taaatatgca aaaatcatgg tgcatagata taaccgtaaa     8940

gagaaaagaa tttctgtgtg gaattaacag ttacacaaat tgggtaacaa ttatcagggc     9000

ctttattata gctttatgtg gaatgttatt ctaaaatgca agagtcaaat gttactgtca     9060

ttgaatattt tagacttgaa acgtgtttat catagagcga agaaaatatg tgttcttttc     9120

tttacagata agactctgtt aacccactgt cagcatacgt gggatttctt ttcttttttc     9180

tttcattagt ggagatttgt tttcatccat ctaccacctt gccagtaccc tagcttgtga     9240

ccagcgggat gcattgtaag aaagttgtct gtggttagga gtgcagtctg ggtccatgga     9300

acaaatttaa actaattggc cctcgcaatg atcagtccta ggaccctggc cttattatta     9360

gcatggtgct ttaaccaatt gtacataata ataccactga tagtctacta atgcatttcc     9420

tagatcccag tttttcttga atgattagga atggtgggga gaggggaggg gagatattct     9480

acatgatact tctccaatct tctaaagatt ataagaaaaa ataaaaaatt gaagtcactt     9540

gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa                                  9573


<210>  2058
<211>  2992
<212>  DNA
<213>  homo sapiens

<400>  2058
aactgagcga ggagcaattg attaatagct cggcgagggg actcactgac tgttataata       60

acactacacc agcaactcct ggcttcccag cagccggaac acagacagga gagagtcagt      120

ggcaaataga catttttctt atttcttaaa aaacagcaac ttgtttgcta cttttatttc      180

tgttgatttt tttttcttgg tgtgtgtggt ggttgttttt aagtgtggag ggcaaaagga      240

gataccatcc caggctcagt ccaacccctc tccaaaacgg cttttctgac actccaggta      300

gcgagggagt tgggtctcca ggttgtgcga ggagcaaatg atgaccgcca aggccgtaga      360

caaaatccca gtaactctca gtggttttgt gcaccagctg tctgacaaca tctacccggt      420

ggaggacctc gccgccacgt cggtgaccat ctttcccaat gccgaactgg gaggcccctt      480

tgaccagatg aacggagtgg ccggagatgg catgatcaac attgacatga ctggagagaa      540

gaggtcgttg gatctcccat atcccagcag ctttgctccc gtctctgcac ctagaaacca      600

gaccttcact tacatgggca agttctccat tgaccctcag taccctggtg ccagctgcta      660

cccagaaggc ataatcaata ttgtgagtgc aggcatcttg caaggggtca cttccccagc      720

ttcaaccaca gcctcatcca gcgtcacctc tgcctccccc aacccactgg ccacaggacc      780

cctgggtgtg tgcaccatgt cccagaccca gcctgacctg gaccacctgt actctccgcc      840

accgcctcct cctccttatt ctggctgtgc aggagacctc taccaggacc cttctgcgtt      900

cctgtcagca gccaccacct ccacctcttc ctctctggcc tacccaccac ctccttccta      960

tccatccccc aagccagcca cggacccagg tctcttccca atgatcccag actatcctgg     1020

attctttcca tctcagtgcc agagagacct acatggtaca gctggcccag accgtaagcc     1080

ctttccctgc ccactggaca ccctgcgggt gccccctcca ctcactccac tctctacaat     1140

ccgtaacttt accctggggg gccccagtgc tggggtgacc ggaccagggg ccagtggagg     1200

cagcgaggga ccccggctgc ctggtagcag ctcagcagca gcagcagccg ccgccgccgc     1260

cgcctataac ccacaccacc tgccactgcg gcccattctg aggcctcgca agtaccccaa     1320

cagacccagc aagacgccgg tgcacgagag gccctacccg tgcccagcag aaggctgcga     1380

ccggcggttc tcccgctctg acgagctgac acggcacatc cgaatccaca ctgggcataa     1440

gcccttccag tgtcggatct gcatgcgcaa cttcagccgc agtgaccacc tcaccaccca     1500

tatccgcacc cacaccggtg agaagccctt cgcctgtgac tactgtggcc gaaagtttgc     1560

ccggagtgat gagaggaagc gccacaccaa gatccacctg agacagaaag agcggaaaag     1620

cagtgccccc tctgcatcgg tgccagcccc ctctacagcc tcctgctctg ggggcgtgca     1680

gcctgggggt accctgtgca gcagtaacag cagcagtctt ggcggagggc cgctcgcccc     1740

ttgctcctct cggacccgga caccttgaga tgagactcag gctgatacac cagctcccaa     1800

aggtcccgga ggccctttgt ccactggagc tgcacaacaa acactaccac cctttcctgt     1860

ccctctctcc ctttgttggg caaagggctt tggtggagct agcactgccc cctttccacc     1920

tagaagcagg ttcttcctaa aacttagccc attctagtct ctcttaggtg agttgactat     1980

caacccaagg caaaggggag gctcagaagg aggtggtgtg gggacccctg gccaagaggg     2040

ctgaggtctg accctgcttt aaagggttgt ttgactaggt tttgctaccc cacttcccct     2100

tattttgacc catcacaggt ttttgaccct ggatgtcaga gttgatctaa gacgttttct     2160

acaataggtt gggagatgct gatcccttca agtggggaca gcaaaaagac aagcaaaact     2220

gatgtgcact ttatggcttg ggactgattt gggggacatt gtacagtgag tgaagtatag     2280

cctttatgcc acactctgtg gccctaaaat ggtgaatcag agcatatcta gttgtctcaa     2340

cccttgaagc aatatgtatt ataaactcag agaacagaag tgcaatgtga tgggaggaac     2400

atagcaatat ctgctccttt tcgagttgtt tgagaaatgt aggctatttt ttcagtgtat     2460

atccactcag attttgtgta tttttgatgt acactgttct ctaaattctg aatctttggg     2520

aaaaaatgta aagcatttat gatctcagag gttaacttat ttaaggggga tgtacatata     2580

ttctctgaaa ctaggatgca tgcaattgtg ttggaagtgt ccttggtgcc ttgtgtgatg     2640

tagacaatgt tacaaggtct gcatgtaaat gggttgcctt attatggaga aaaaaatcac     2700

tccctgagtt tagtatggct gtatatttct gcctattaat atttggaatt ttttttagaa     2760

agtatatttt tgtatgcttt gttttgtgac ttaaaagtgt tacctttgta gtcaaatttc     2820

agataagaat gtacataatg ttaccggagc tgatttgttt ggtcattagc tcttaatagt     2880

tgtgaaaaaa taaatctatt ctaacgcaaa accactaact gaagttcaga taatggatgg     2940

tttgtgacta tagtgtaaat aaatactttt caacaataaa aaaaaaaaaa aa             2992


<210>  2059
<211>  2533
<212>  DNA
<213>  homo sapiens

<400>  2059
gcgggtgtgt gtgtgtgtgg atgtgtgtgg ggtgtgggtg tcccttacgc ccttcctcct       60

ctccctcctc ctcctgctcc cccctccttt ccttctcctc ctcccccctc tcctctccct      120

cctcctggtc ctcatcgccc ctctcctcct cttcctcccc tctctcttcc tctccctgaa      180

ttttctcctc tcctctcagg tcagtccatg gtattccgct cccccctaga cctctattcc      240

tcccacttct tgttgccaaa cttcgccgat tctcaccacc gctccatact tctggcgagt      300

agcggcggcg ggaacggtgc gggaggcggc ggcggcgcgg gaggcggcag cggcggcggg      360

aacggtgcgg gaggcggcgg tgctggcgga gcaggcggcg gcggcggcgg cggctccagg      420

gcccccccgg aagagttgtc catgttccag ctgcccaccc tcaacttctc gccggagcag      480

gtggccagcg tctgtgagac gctggaggag acgggcgaca tcgagcggct gggccgcttc      540

ctctggtcgc tgcccgtggc ccccggggcg tgcgaggcca tcaacaaaca cgagtcgatc      600

ctgcgcgcgc gcgccgtggt cgccttccac acgggcaact tccgcgacct ctaccacatc      660

cttgagaacc acaagttcac caaggagtct cacggcaagc tgcaggccat gtggctcgag      720

gcgcactacc aggaggccga gaagctgcgc ggccgcccac tcggcccggt ggacaagtac      780

cgcgtgcgca agaagttccc gctgccacgc accatctggg acggcgagca gaagacgcat      840

tgcttcaagg agcggactcg gagcctgttg cgggagtggt acctacagga cccctacccc      900

aaccccagca agaaacgcga actggcgcag gccaccggcc tcactcccac acaagtaggc      960

aactggttta agaaccggcg gcagcgcgac cgcgccgcgg cggccaagaa caggctccag     1020

caccaggcca ttggaccgag cggcatgcgc tcgctggccg agcccggctg ccccacgcac     1080

ggctcggcag agtcgccgtc cacggcggcc agcccgacca ccagcgtgtc cagcctgacg     1140

gagcgcgcag acaccggcac ctccatcctc tcggtaacct ccagcgactc ggaatgtgat     1200

gtatgatagc caaggccgcc ctcctccctc tccttcccct cctcccccac tccttcccct     1260

ccgcctccta gccctcctcc tcttcctcct cttccttctc ctcctccatc cccagaacaa     1320

accgaaatca ggatacccaa ccatacacac atacaagtcc acacacactc ccaccccagc     1380

caaaaatata taaaaaacaa gaaaataaca aattaaccgc aaactatcaa caacccccaa     1440

ccaccatcta ccactacggc caccccaaag gaccccgacg ccaacagaca gtcaaacgct     1500

gatgttgcgg gcagaaaaca taaaagaggt gacaattgta tactttctag gacaagcacg     1560

gcttctcctt tcggttccca tggacccggc accccacctg catgacgatt tatttgtatc     1620

tgggaaaata ttctctctag ttaaaaatga tttaaagagt cgactataca aaaatcaatc     1680

accaccacga ggacaagagg gcaaaagcaa aacagacaaa aagaaaaaaa atcgccgtct     1740

ccgttccgaa tttgttaaaa aaaaaaaaaa aaaaaaaaaa aaggacaggg ggaaaaaaaa     1800

aaaaaaagaa ctcctggaga gggaaatagc aaatgtgtct tgccttttgt tgctctctct     1860

ctcttttttt ttctctcgct ctctttcttt ctcttcttct ctctgttttt aagtcaagta     1920

ttggtcaaaa aaatgcaatc ttctgttttt tgttcagcag acaatcattt tcttcgtaag     1980

cacctttttc tctccactct gtcactgcct gtgtgggtac tggttataaa tgtggaaaaa     2040

gaatagttat gactgtaaca gatttttatt tttatttcaa aattttatat gaattatgta     2100

tatcttaatg atcggtcatt ttcccagttt gtaatatatg tgtagaaatt gcctgtatat     2160

gatattgctt tttctcctct ccctttctct ttctctcctc tccctctctc tgtctttctc     2220

cccgctcaac tgtctctttt ctttttgggg ttctcctccc actcggtgct cctggtgtcg     2280

acttggcagt caaggagagg catggtggcc tgggttagga agagggaccc tgtcgctagc     2340

aaaagcggag agtgagattg tagtattctt atgcaaaagc tatttccagt atttcttagc     2400

agcttcagag gtatctctca ctccctgtag ggcgctttta ctgttatctt aaactgcgtg     2460

tttatctata tgtaaaaact ttctaaagca aatacagtat tctccatttt cttatcactc     2520

ccaaaaaaaa aaa                                                        2533


<210>  2060
<211>  1964
<212>  DNA
<213>  homo sapiens

<400>  2060
ggcgccgctg cgggagaggc ccggtctgga gtttgcggag ggccgagccg ggtgcgcacg       60

gggaggcgga ggcagcggcg gcggcggcgg cggcggcggc ggcggcggag cagatgaaga      120

aactgaggcc ctgtgatgtg aagtgacttg ccccccagcc acacagctgg accattctgg      180

ctgctgtctg gacaagaagt cgtagggggt gagggtggaa gctgggaaac ccacaggagg      240

caaccacact agtttagatc ttctggtgac cccacttctc gctgctcatg ccgctgggac      300

tggggcggcg gaaaaaggcg ccccctctag tggaaaatga ggaggctgag ccaggccgtg      360

gagggctggg cgtgggggag ccagggcctc tgggcggagg tgggtcgggg ggcccccaaa      420

tgggcttgcc cccccctccc ccagccctgc ggccccgcct cgtgttccac acccagctgg      480

cccatggcag tcccactggc cgcatcgagg gcttcaccaa cgtcaaggag ctgtatggca      540

agatcgccga ggccttccgc ctgccaactg ccgaggtgat gttctgcacc ctgaacaccc      600

acaaagtgga catggacaag ctcctggggg gccagatcgg gctggaggac ttcatcttcg      660

cccacgtgaa ggggcagcgc aaggaggtgg aggtgttcaa gtcggaggat gcactcgggc      720

tcaccatcac ggacaacggg gctggctacg ccttcatcaa gcgcatcaag gagggcagcg      780

tgatcgacca catccacctc atcagcgtgg gcgacatgat cgaggccatt aacgggcaga      840

gcctgctggg ctgccggcac tacgaggtgg cccggctgct caaggagctg ccccgaggcc      900

gtaccttcac gctgaagctc acggagcctc gcaaggcctt cgacatgatc agccagcgtt      960

cagcgggtgg ccgccctggc tctggcccac aactgggcac tggccgaggg accctgcggc     1020

tccgatcccg gggccccgcc acggtggagg atctgccctc tgcctttgaa gagaaggcca     1080

ttgagaaggt ggatgacctg ctggagagtt acatgggtat cagggacacg gagctggcgg     1140

ccaccatggt ggagctggga aaggacaaaa ggaacccgga tgagctggcc gaggccctgg     1200

acgaacggct gggtgacttt gccttccctg acgagttcgt ctttgacgtc tggggcgcca     1260

ttggggacgc caaggtcggc cgctactagg actgcccccg gaccctgcga tgatgacccg     1320

ggcgcaacct ggtgggggcc cccagcaggg acactgacgt caggacccga gcctccagcc     1380

tgagcctagc tcagcagccc aaggacgatg gtgaggggag gtggggccag gccccctgcc     1440

ccgctccaat cggtaccatc ccctccctgg ttcccagtct ggccggggtc cccggccccc     1500

ctgtgccctg ttccccacct acctcagctg ggtcaggcac agggagggga gggatcagcc     1560

aaattgggcg gccacccccg cctccaccac tttccaccat cagctgccaa actggtccct     1620

ctgtctccct ggggccttgg gttctgtttg ggggtcatga ccttcctagt ttcctgacgc     1680

agggaataca ggggagaggg ttgtccttcc ccccagcaaa tgcaataatg ccctcacccc     1740

tcctgagagg agccccctcc ctgtggagcc tgttacctcc gcatttgaca cgagtctgct     1800

gtgaaccccg caacctcctc cccacctccc atctctcctt ccaggcccat ccctggccca     1860

gagcaggagg gagggaggga cgatggcggt gggtttttgt atctgaattt gctgtcttga     1920

acataaagaa tctatctgct gttggaaaaa aaaaaaaaaa aaaa                      1964


<210>  2061
<211>  1504
<212>  DNA
<213>  homo sapiens

<400>  2061
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgaggta agcggtggcg ccttgggcgg cgcacttgct gggtgacttg gagggcatcg     1020

gctagctgac attggtgatc tgacggcagc caagcccagc tcggatcaag gtcccttcat     1080

gcgcggtgtc tctgcgcctg agtaacgaca tggaactgaa agaccagagg gacactagga     1140

atcaaaacaa acatttctat tctgcttagt ttttctgttt tgtaaatctt tctttcttaa     1200

ccactttcag cccctgggat tctagaactg tgaattgtgc tctgttgtag ggggcagggg     1260

aagctctcac tctgttgcca ttaaatgtat gagactgggc atctctgagc aattgtaggg     1320

ccggggatag agggtacttg aatcttcaga agttgaagta gcttttatgc cctcaggaaa     1380

ggccctggtc tccggagttt cctcgcatta aaggagagag agagagagta ctcttttggg     1440

caacggccct ccaaaattgc ccccacattg gctgccttat aaatatgtct gtgtgttgac     1500

tggt                                                                  1504


<210>  2062
<211>  3356
<212>  DNA
<213>  homo sapiens

<400>  2062
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca aggtgacaac gcctgacgtg      720

gagaagaaaa ttgaggaata caaaagagag aacccgggca tgttcagctg ggaaatccga      780

gacaaattac tcaaggacgc ggtctgtgat cgaaacaccg tgccgtcagt gagttccatc      840

agccgcatcc tgagaagtaa attcgggaaa ggtgaagagg aggaggccga cttggagagg      900

aaggaggcag aggaaagcga gaagaaggcc aaacacagca tcgacggcat cctgagcgag      960

cgagcctcag caccccaatc agatgaaggc tctgatattg actctgaacc agatttacca     1020

ctaaagagga aacagcgcag aagccgaacc accttcacag cagaacagct ggaggaactg     1080

gagcgtgctt ttgagagaac tcattaccct gacatttata ctagggagga actggcccag     1140

agggcgaagc tcaccgaggc ccgagtacag gtctggttta gcaaccgccg tgcaagatgg     1200

aggaagcaag ctggggccaa tcaactgatg gctttcaacc atctcattcc cggggggttc     1260

cctcccactg ccatgccgac cttgccaacg taccagctgt cggagacctc ttaccagccc     1320

acatctattc cacaagctgt gtcagatccc agcagcaccg ttcacagacc tcaaccgctt     1380

cctccaagca ctgtacacca aagcacgatt ccttccaacc cagacagcag ctctgcctac     1440

tgcctcccca gcaccaggca tggattttcc agctatacag acagctttgt gcctccgtcg     1500

gggccctcca accccatgaa ccccaccatt ggcaatggcc tctcacctca ggtaatggga     1560

ctcctgacca accacggtgg ggtacctcat cagccccaga ctgattacgc gctctcccct     1620

ctcaccgggg gtctggaacc taccaccacg gtgtcggcca gctgcagtca gagactagac     1680

catatgaaga gcttggacag tctgccaaca tctcagtcct actgtccacc cacctatagc     1740

accacaggct acagtatgga ccctgtcaca ggctaccaat atgggcagta tggacaaagt     1800

gcctttcatt atctcaagcc agatatcgcg taagtgaact gtccacttgg agctaaaact     1860

ggccctgttt ctggtcttcg cagcctagat atgaagaatc tgctctgaaa acaaaaaaaa     1920

attacccttt tgttgggggg ggtggggcag tggtcccaat aggagacaaa ggagagtgat     1980

tgattttctt cctccaatag ttggtttcaa atccttttga acacgttcga caaaagcagt     2040

ggagaagagg aagacctgga gcaataaaag acaaatgcaa cattttaagg caatggtttc     2100

acatggttac atatcaaaac atcccaattc tttagtgctg atcatcgagg agctagaaca     2160

ttccatttgc ttgtgtgcgt gcgtgcgtgt gtgtgtgtgt gtgtgtattg agatttaccc     2220

agactggttt gggcaagcag actgttctaa aatataatag aataccctaa agtataacat     2280

gtcgatgttc gatgctgata cttctacaac tttaaaactg ctcatttcat gaagcaagaa     2340

tggaggaatc cttgactctt acacactgga aattgaaata aagataaatg caaccatttt     2400

taggaagcta gactagctgt aaaggacctc ctaaataaat tatttgttac tgtatcctca     2460

tttgtaatct agttgtcaat aaatggcccg gacatgtctt gctaacagga tatgggctac     2520

caggaagaag gacttgtttc cctttcctgt gtggggagag gtgtgtgacg tttttccagt     2580

tcacatttat ttggtagccc acctgggttg gaggaagggc acggtggaga gaaagtgaca     2640

tgcattcaca tatctgctta tcagtgtgca atactgtgta cctcatggat gctttggcaa     2700

tgcccaaggc gatataagca aaatcagaag tatatttttg caggtgcttt tattttcaca     2760

gcccataatt catagtgata gagtgcagtg atgtttgcca tttgctggac aaccaacacc     2820

cgggttgctc ctttgattag agaccagatc agataattat gcttttaaac tgattacgtt     2880

tacattcttc tcttttctat gaaaggcagg gcaagaacag aagtgttcac atggctctca     2940

tgtactttta aattatacaa tgatatccaa tattaaaaga ttataggaac tgaggtttac     3000

atacgtttgt gtggtgacat tttagaatgt caataaattt gctttttgag atgttgagag     3060

gaacaagaag gtggaaggca gtgttattta tttctttcta ttcttggaac cacgaatgag     3120

gtaggcacaa atacattcct tttagagtta agaactatga cgtagcgagt tagtgagact     3180

agacatagta ccgaatttag ttcatgcatt ggtcttagag ggtgatggaa caagagaagt     3240

actatctttg tgttgcagcc tcaaccaaca acaatgtgtt gtaaaaatgt ctttcatgta     3300

aaaagtgcag taaatattta ctatttataa tgaataaaca gttatgaaaa cttgaa         3356


<210>  2063
<211>  9171
<212>  DNA
<213>  homo sapiens

<400>  2063
atttcatttc ttccactaaa gcgtttgcgg agacttcaag gtataatcta tcccagatcc       60

tttcccagag agaaacttgg cgatcacgtt ttcacatgat gctcacgctc agggcgcttc      120

aattatccct ccccacaaag ataggtggcg cgtgtttcag ggtctctcgt ctctctccta      180

cagaaaagaa aaagaaaaaa atgtcattag aagaggcgta acacgtcagt ccgtccccag      240

gtttgtgttt cctggagtgg ccgaaagaga tcagttctaa cctgctctgc aggaataacg      300

gtcctgcctc ccgacactct tggcgaggtt tttgtacagt ttgctccggg agctgtttct      360

tcgcttccac ctttttctcc cccacacttc gcggcttctt catgcttttt cttctcacca      420

tttctggcca aaactacaaa caagacttcg cagatcgagc ctgcgtgctg ccgaagcagg      480

gcgccgagtc catgcgaact gccatctgat ccgctcttat caatgaagca gccgatcatg      540

gcggatggcc cccggtgcaa gaggcgcaaa caagccaatc ccaggaggaa aaacgtggtg      600

aactatgaca atgtagtgga cacaggttct gaaacagatg aggaagacaa gcttcatatt      660

gctgaggatg acggtattgc caaccctctg gaccaggaga cgagtccagc tagtgtgccc      720

aaccatgagt cctccccaca cgtgagccaa gctctgttgc caagagagga agaggaagat      780

gaaataaggg agggtggagt ggaacacccc tggcacaaca acgagattct acaagcctct      840

gtagatggtc cagtgaagaa tgcaaattgc acatcagatt ttgaggaata ctttgccaaa      900

agaaaactgg aggaacgcga tggtcatgca gtcagcatcg aggagtacct tcagcgcagt      960

gacacagcca ttatttaccc agaagcccct gaggagctgt ctcgccttgg cacgccagag     1020

gccaatgggc aagaagaaaa tgacctgcca cctggaactc cagatgcttt tgcccaactg     1080

ctgacctgcc cctactgcga ccggggctac aagcgcttga catcactgaa ggagcacatc     1140

aagtaccgcc acgagaagaa tgaagagaac ttttcctgcc ctctctgtag ctacacgttt     1200

gcctaccgca cccagctcga gcggcatatg gtgacacaca agccagggac agatcagcac     1260

caaatgctaa cccaaggagc aggtaatcgc aagttcaaat gcacagagtg tggcaaggcc     1320

ttcaaatata aacaccatct gaaagaacac ctgcgaattc acagtggtga aaaaccttac     1380

gagtgcccaa actgcaagaa acgtttctcc cattctggtt cctacagttc gcacatcagc     1440

agcaagaaat gtattggttt aatctctgta aatggccgaa tgagaaacaa tatcaagacg     1500

ggttcttccc ctaattctgt ttcttcttct cctactaatt cagccattac ccagttaaga     1560

aacaagttgg agaatggaaa accacttagt atgtctgaac agacaggctt acttaaaatt     1620

aaaacagaac cactagactt caatgactat aaagttctta tggctacaca cgggtttagt     1680

ggcactagtc cctttatgaa tggtgggctt ggagccacca gccctttagg agttcatcca     1740

tctgctcaga gtccaatgca gcacttaggt gtagggatgg aagccccttt acttgggttt     1800

cccaccatga atagtaattt aagtgaggta caaaaggttc tacagattgt ggacaatact     1860

gtttccaggc aaaaaatgga ctgcaaggct gaagaaattt caaagttgaa aggttatcac     1920

atgaaggatc catgctctca acctgaggaa caaggagtta cttctcctaa tattccgcct     1980

gtcggtcttc cggtagtgag tcataatggt gccactaaaa gtattattga ctatacgttg     2040

gaaaaagtca atgaagccaa agcttgcctc cagagcttga ctactgactc aaggagacag     2100

atcagtaata taaagaaaga gaagctacgt actttaatag atttggtcac tgatgacaaa     2160

atgattgaga accacaacat atccactcca ttttcatgcc agttctgtaa agaaagtttt     2220

cctggcccca tccctttgca tcagcatgaa cgttaccttt gtaagatgaa tgaagagatc     2280

aaggcggtcc tgcagcctca tgaaaacata gtccccaaca aagccggagt ttttgttgat     2340

aataaagccc tcctcttgtc atctgtactt tctgagaaag gaatgacaag ccccatcaac     2400

ccatacaagg accacatgtc tgtactcaaa gcatactatg ctatgaacat ggagcccaac     2460

tccgatgaac tgctgaaaat ttccattgct gtgggccttc ctcaggaatt tgtgaaggaa     2520

tggtttgaac aacgaaaagt ctaccagtac tcaaattcca ggtccccatc cctggaaaga     2580

agctccaagc cgttagctcc caacagtaac cctcccacaa aagactcttt attacccagg     2640

tctcctgtaa aacctatgga ctccataaca tcaccatcta tagcagaact ccacaacagt     2700

gttacgaatt gtgatcctcc tctcaggcta acaaaacctt cccattttac caatattaaa     2760

ccagttgaaa aattggacca ctccaggagt aatactcctt ctcccttaaa tctttcctcc     2820

acatcttcta aaaactccca cagtagttca tacactccaa acagcttctc ttctgaggag     2880

ctccaggctg agcctttaga cttgtcatta ccaaaacaaa tgaaagaacc caaaagtatt     2940

atagccacaa agaacaaaac aaaagctagt agcatcagtt tagatcataa cagtgtttct     3000

tcctcatctg aaaactcaga tgagcctctg aacttgactt ttatcaagaa ggaattttca     3060

aattcaaata atctggacaa caaaagcact aacccagtgt tcagcatgaa cccatttagt     3120

gccaaacctt tatacacagc tcttccacct caaagcgcat ttccccctgc tactttcatg     3180

ccaccagtcc agaccagtat tcctgggcta cgaccatacc caggactgga tcagatgagc     3240

ttcctaccac atatggccta cacctaccca actggagcag ctacttttgc tgatatgcag     3300

caaaggagaa agtaccagcg gaaacaagga tttcagggag aattgcttga tggagcacaa     3360

gactacatgt caggcctaga tgatatgaca gactccgact cctgtctgtc tcgcaaaaag     3420

atcaagaaga cagagagtgg catgtatgca tgtgacttat gtgacaagac attccagaaa     3480

agcagttccc ttctgcgaca taaatacgaa cacacaggaa aaagaccaca tcagtgtcag     3540

atttgtaaga aagcgtttaa acacaagcac caccttatcg agcactcaag gcttcactcg     3600

ggcgagaagc cctatcagtg tgataaatgt ggcaagcgct tctcacactc gggctcgtac     3660

tcgcagcaca tgaatcacag gtattcctac tgcaagcggg aggcggagga gcgggaagcg     3720

gcggagcgcg aggcgcgcga gaaagggcac ttggaaccca ccgagctgct gatgaaccgg     3780

gcttacttgc agagcattac ccctcagggg tactctgact cggaggagag ggagagtatg     3840

ccgagggatg gcgagagcga gaaggagcac gagaaagaag gcgaggatgg ctacgggaag     3900

ctgggcagac aggatggcga cgaggagttc gaggaggaag aggaagaaag tgaaaataaa     3960

agtatggata cggatcccga aacgatacga gatgaagaag agactggaga tcactccatg     4020

gacgatagtt cggaggatgg gaaaatggaa accaaatcag accacgagga agacaatatg     4080

gaagatggca tgtaataaac tactgcattt taagcttcct attttttttt ccagtagtat     4140

tgttacctgc ttgaaaacac tgctgtgtta agctgttcat gcacgtgcct gacgcttcca     4200

ggaagctgta gagagggaca gaaggggcgg ttcagccaag acagatgtag acggagttgg     4260

agctgggtat tgttaaaaac tgcattatgc aaaaattttg tacagtgtta aggcctaaaa     4320

actgtgtggt tcagagacta attcctgtgt ttaatagcat ttatacttta agcacaacta     4380

gaaaattgta agaattgcac tctacttatg tatcactaca aactttaaaa aactatgtct     4440

aatttatatt aatacatttt aaaaaggtgc ccgcactacc atacatcagt atttttatta     4500

ttattattgt tattcctttt taatttaatg tgctcgcact acaatgcatc agtattatga     4560

ttcctctgta ctttcctttc gctattcatc aatttcccat tttttttttc agcttaagta     4620

accacacaat tttaggcctc aatttttttt tttttctgtg aaggaacttg aagtgatgca     4680

tgtgtgaatt taagataccg aagtcttaaa gtgacctgga cgtgaaggaa aaagtaagat     4740

gagaaataaa gaaagccttt gtaaggtggt tttaaaagcc ttatatgcaa accttttaat     4800

ctgtgtttct gcaagtgcca tccttgtaca gtgttaagag ggtaacatgg gttacctttg     4860

caccagcttc agtgttaagc tcaccctgtt ctttgaagca cccatgtcag tattagaaga     4920

ataggcagca gttccttagt ttacatatgt ttgtgcaatt attttctgta cttttttgtt     4980

cattaatttt gtcagtatta caccaaactg tttttgcaac aaaaaaattt tttttgcatt     5040

catttaattt taggtcaaat aacattttat ttatgtggct cattttatat ttcctaattt     5100

tatttatttc atactgtagt gtacagtatt atagttcttc aatatataga tatattttag     5160

taaaaaagga acatgacgtt gatcatttgg gcaaatttta cgtaaagaga agagcattta     5220

ttgtgttttg gaacattaat tgtgagatgg gatttttcaa ttttattatt ttatttttgt     5280

ttttttccaa ttactggaaa ttccaaattt gggaactttt gatacgatct tgtgaaaaca     5340

ctgtattttc gactgaaaat tccactttct tcatcttgtt ttttagctaa aaagagggac     5400

tgttaaatac aatgtatgat accatgacaa aaatctttcc tgaattgtct ttgtaaaagt     5460

attattgaat tttcaatttg taatttcttt tgaaaatgac catgctcgaa taaaaatgta     5520

gccaaactaa gaatgtagtt aatgagttct gtacttttag agagttttcc ttcaatgacc     5580

attaacatgt aacatgcttt atgcttataa taatgctaat tatgtttttt tcatataatt     5640

ttagtttagc aataattttg actggtacca ataactgttt tttaaaattc catacctatg     5700

tacagcaatt ttacagcttt tctcaactga tcctgattcc agattgtgta tttttatgtg     5760

aggttatatt attcaaattt agtctattta ctttacagac atttctactt ttgcattacg     5820

agtatttaga gattatgtgt taaaaattca cttctctgtc caaggggtct ttgtgattta     5880

ttcaaaaaaa agtctaattt caaaaagaca gctattattc agtgttattt ataatatgta     5940

acctttttta aaggattggg atagtttatc tcactttttg aaatgcagac agtagtttac     6000

cgtttatctg aaactagaag gcgtgggtgg gagaggaaaa gctaaaagca aatgctaaca     6060

aaaataaccg tgattttcta agacagtttt tcagttttta caagatgacc ctaatattca     6120

gaatatgaat gtattcgtag gttttacata atgactttta tcaagaaact agattctgct     6180

tcttaaatct aattgccaag tgaagaataa cagaaaaaac agattacctt atcaaattta     6240

cagctcttga atatacagaa ctataatata gtagctgtcc atgtattttt tctactttag     6300

aatcaaagaa gaaaagcatc attttgctat taaatttgct aaaattttga gtatgatatt     6360

tccagttggc aagaacaaca tatttatatt tattccttag ccataatacc actttcctaa     6420

atttcacaaa agtcattctt tgcaacttga aactcaatag aaagtgtgta tgtgtgtgtg     6480

tgtatatata tatatatata cacacacaca catacacaga aaggatgtaa tgaagataca     6540

gtaatagttg agcagacctt tttagaaaaa catgttttta gctctatctt caaactttct     6600

ggcagagggg gtgggggggg cagggggagg agtggcatca aaatgctatg cctcctgtta     6660

tccacagcct agagttttta tatttggaaa gtttagaaaa ttctatcctc gtttctcctt     6720

ctttgaatgg cacaaataaa tacactacat aaatttttct ggtttgaaag gctctaggcg     6780

ataactttat taattcaacc tgaaaatatc aagccattaa attttgtccg ggtagaataa     6840

atccctgtgg cctcttttaa agcaatgtag gtctctgttg cccatggggc atatctgtgt     6900

cccaatccac aagagatagg accaacaaac aatgaatgtg caacctaact ctttctcctt     6960

ggaaagaaga aagtgtgcac gaagtagagg agggtgggca gaccctgcct tgcccctcct     7020

gttaccccct tctctgtcat ttgttcctaa ctccatttca taggcaggct cagaatacct     7080

gagtctgaaa atatcaggat aacacttgtg aattgtgaca atcactacaa tgtcccatat     7140

ctgaggagtt ttttttaatg ctatttatcc gctggacacg attgcacatt agggctgcat     7200

aatcctctaa ctctagggaa aaataaaaac ttttgatttg tcttaagatt cttctccaag     7260

gtcgcaaaca agaaattccc ctccacaacc aagagatgtg cattttagta acatcagatg     7320

tgttcttctg ttttatcaac tacttactct tcccacacgc ttagttctaa atctaacctt     7380

tcccccctcg aatagggggc aggggaggat gaggaaacac tggaacaact gaacacccct     7440

gcccattttc tccaagagcc ttttgtattc tagcatatct gtgcaatctt ttcttttttc     7500

ttcacatgac actgtaagct taggcctgaa ataactggga agagagatgc gtatcagaat     7560

ttctccgcaa gagctaaaca aaacatacat cttccttagc atgaattgga ctgggggcgg     7620

agtgggaggg cttggaggaa aggggaaaga agggactata tttgaataaa tatgaataaa     7680

tgtattagat acttttcaca atcagataac ttttaaaaag gtcatttttt atctttctaa     7740

taatgtaagc cttaataaaa gcaaatctta gtcacaaatt tgaggagact gcccaataat     7800

aagtttacat gtatttgaac tgaaaaattg ttaaccatgc ttttgctcca agatgtgtga     7860

ggccattcag gggctgtagg gccctggata tacacacaaa caagtgtgtg tatatctgga     7920

gccccacaca ttgtaataaa cacagctgca tttatttgac tatgtgatcc catgtacatg     7980

taaaaacatt caaacaaaca cactcagcgg atttatttat tgtgcaatgg ggcaattatt     8040

caaataaaca tgctcaatgc aattatttga atctcacatt gcatgttcat caatcatagc     8100

actaaaaaaa gagggggaaa aaacaccaaa gaattcacat ggggaaaaaa tatatatatg     8160

aaaaccacct tattatagat tttatagggc agctgaggtt atggctccct tcttaactgt     8220

aactcaacta ttctgtattc aatgacattt gtttctaatg attaattggt tcactcactt     8280

gatcatataa tagcaaactt tataaacctg tattgtgtag agatgtgaaa tctctatatt     8340

tcaagagcag aagagttctt tctagacacc ttacatcaag ggacactggt ccaattatta     8400

tcgcttatat aagcactcct ataaattctg aaaaatttta tacatgcaac aaaacattcc     8460

tacatttgaa gacattaaga aaaatcacag gtgactcatc tgatcattct atatattaat     8520

aaatattatg acatatatgt gaacacatca caaatcatat tggtgtacca agaggcaatt     8580

tatgcctctc ttaagtatgt actgacataa cctaatatac taaaatggga aggggctttt     8640

agtcactgaa atatgcatcg tgtaacaaag atgaagaaaa tacatggctt gtgcccatca     8700

taaaaaaaga ttcagactga aggcttagct ttggtttttt caattaaatt gttaaactgt     8760

gcacagtgat ttttttttag aacttgagac atttgtgatg ttggctgttt aaatctttgt     8820

taccttcgct gtgaattgaa attgtacata tttagtaaat catgcagaca aaacaaactt     8880

tttagacaat atttttattg gagagttttc ttttcctgta tccatgttaa aaaaaaaaaa     8940

gacctccttt cccaaaataa aaatgtcaat actaaattta aagaagtata aaggaatgat     9000

tgcttccttt agagcaaaat atttaaataa acatggagat aattggcaac atgttctttt     9060

tgggctagta ggctgtgtcc aattttttgg gtctgatgtt tcagagggcc tctgtttcag     9120

ggttgaagat gatatattaa tctcggaatt aaacaaatgc tattaaataa c              9171


<210>  2064
<211>  937
<212>  DNA
<213>  homo sapiens

<400>  2064
tgcgtgccgc cgttgatccg gtgctgcagt gaggaggtgg ttcttgcccg tgttgtgtgt       60

gtgtgtgagt gagagagcga gtgagtgagt gagtgagtgt gtgtgtgggg gggactcggc      120

ttgttgttgt cggtgacttc cccctcccct tcaccccttc ccctccccgc cgccgctgca      180

gtggccgctc cctgggccgt aggaaatgag cgataacgat gacatcgagg tggagagcga      240

cgaagagcaa ccgaggtttc aatctgcggc tgacaaacgg gctcatcata atgcactgga      300

acgaaaacgt agggaccaca tcaaagacag ctttcacagt ttgcgggact cagtcccatc      360

actccaagga gagaagctct atttcctctt ttggaaattg tgtactcctg tccttcatcg      420

tcaaagtttg atgcagaaat gccacacctt catttcaagc taccaagtgc acaagaaaaa      480

agaatgcaag atttaaaaaa tgattgtttt gaccccttac acaaatgtct tactcctggc      540

tttaattaag ctgcttgagg gctgatagct ctgccttacc ctggtaatca gcaaaatggt      600

cctgtggctg gggaggccct ggcagcagga agccttcaag gagccatggg tctgtgctga      660

ctctggcctt acaaccttcc agcctccttt gctggcattg atggggttcc atttttgaat      720

gaactagttt aatgtggatc caaatttatt gtgcatattc tttcgttttg gttttcaaaa      780

gatggcttat tcacatggaa atgtacacca gtttagccct gggccctccc tttaccttca      840

tatgtgtaaa agcttacaca ggtttcagaa aataaatggt ttcattttct ctaaaataac      900

tagtacaaaa taaaacagat gtcagttgtt gagtcca                               937


<210>  2065
<211>  6540
<212>  DNA
<213>  homo sapiens

<400>  2065
cggcccagcc gagccgggct gcttgtctgg ccggcggagg ctgagcgcga ccctagcaag       60

ccgcggcgcc cgccgaccag ggacaagagc gactcctggg accccactct gccccgcgcc      120

gccgcctcct cccctgttgt cgcggggacg ctcaggcccg cgccgcccgg gccacgattc      180

tcctcctctt tctcccggag gggaaggaac ggagaaagcc gagcggcggc tccgggagag      240

agcgagccga ggcccctgcc cccgaggctc ggggcaggag gaggaggagg aggaggaggc      300

ggaggcggag ggaagtgcgc gtcactctcg ggaggagagt atttcacctc caggcagagg      360

ctgcggctgc cagttgagta cgagcggcag ctgcgggcgc cggcaatcga gtggcttcct      420

ggccatggag aggagatctg gacccgagga cgccagggac tcctctccgt ctccctggac      480

cgctgtgtag gcacctgagt taacggacgc taagcggggt aggggaagta acagtgtatc      540

atgtatgcca ctgattccag gggacactcc cctgctttcc tccaacctca gaatggaaat      600

agtcgtcacc catctggcta tgttccaggg aaggttgtcc cattgcgtcc ccctcctcct      660

ccaaagagtc aagcttcagc caaatttacc tccatcagac gagaagaccg ggcaaccttc      720

gcattctcac ctgaagaaca gcaagcccag agagaaagtc aaaagcaaaa gagacacaaa      780

aatactttca tttgttttgc tattactagt ttctcatttt ttattgcact tgcaatcatt      840

ttaggaatat cctcaaaata tgctccagat gaaaattgcc cagatcaaaa tcctcgtctc      900

aggaattggg atccaggaca agattctgca aagcaagttg ttatcaagga gggagatatg      960

ctccgtctga cctcagacgc caccgtgcat tctatagtca ttcaggatgg aggactgctt     1020

gtatttgggg acaataaaga tggatccaga aatattactt tgaggactca ttacatcctg     1080

atccaggatg gtggggcgct tcatattgga gcagaaaaat gccgctataa atccaaagcg     1140

acaattacct tgtatggcaa gtcagatgaa ggtgaaagta tgccaacatt tggcaaaaag     1200

tttattggtg tggaagctgg cgggacactg gagttacatg gggcacggaa ggcatcgtgg     1260

acgttgttgg caaggaccct gaattcctca ggcttgccct ttgggtccta tacctttgaa     1320

aaggactttt cccggggcct caatgtgagg gtcattgacc aagacacggc caaaattttg     1380

gaaagtgaga gatttgatac ccatgaatac cgcaatgaga gcaggcggct tcaggagttt     1440

ctgagattcc aggatccagg tcggattgtt gccatagctg tcggggattc agccgctaaa     1500

agtctcttac aaggaaccat ccagatgatc caggaacggt tgggaagtga actgatccaa     1560

ggactgggct acaggcaagc ttgggcttta gttggtgtca ttgatggtgg aagcacttct     1620

tgcaatgaat ccgtgagaaa ctatgaaaat catagcagtg gcgggaaggc tcttgcccaa     1680

agagaatttt atactgtgga tggccagaag ttctctgtga cagcttatag tgaatggatt     1740

gaaggcgttt ctctttcagg attccgggta gaggttgtag atggagtgaa gctaaatttg     1800

ctagatgatg ttagtagttg gaaacctgga gaccagattg tggtcgcaag cacagactat     1860

tccatgtacc aagcagagga gttcactctt cttccctgtt ctgaatgcag ccattttcag     1920

gtcaaagtca aagaaacccc tcagttcctg cacatgggtg agatcataga cggtgtagac     1980

atgagagctg aggttggaat tcttacccgg aatattgtga tccaaggaga agtggaggac     2040

tcatgctacg cagaaaatca gtgccaattt tttgattatg atacctttgg gggacacatt     2100

atgataatga aaaattttac ttcagtccat ctttcttatg tggaattgaa acacatgggt     2160

cagcagcaga tggggcgata ccctgttcat tttcacctgt gtggtgacgt ggattataaa     2220

ggaggataca gacatgcaac atttgtggac ggcctgtcta ttcatcacag cttctcaagg     2280

tgcatcactg tgcatgggac aaatggcttg ctaataaaag acaccattgg gtttgacaca     2340

ctaggtcatt gtttcttttt ggaagatggt attgaacaga ggaatacttt gttccacaat     2400

ctgggactcc tcaccaagcc gggtactctc ctgcccaccg ataggaacaa ctccatgtgt     2460

accaccatgc gagataaagt gtttggaaat tacattcctg tgcctgctac tgactgtatg     2520

gctgtttcaa ctttctggat tgctcatccc aacaataatc tgattaataa tgcagctgca     2580

ggctcacagg atgctggaat atggtattta ttccacaagg aaccaactgg ggaatccagt     2640

ggattgcagc tcttggcaaa accagaactc actccattgg gtatatttta taacaacagg     2700

gtccattcaa attttaaggc tggcttattt attgacaaag gtgtcaaaac aaccaactct     2760

agtgctgctg acccaaggga atacctctgt ttggacaata gtgcaagatt tcgacctcat     2820

caggatgcaa accccgaaaa accacgtgtt gctgctctaa ttgacaggct cattgctttt     2880

aaaaataatg ataatggagc ttgggtcaga ggaggagata ttatcgttca aaattcagca     2940

tttgcagata atggaatagg actgaccttt gccagtgatg gaagcttccc aagtgatgaa     3000

ggttccagcc aagaggtatc tgaatctctc tttgttgggg agagcaggaa ttacggcttt     3060

cagggtggtc agaacaagta tgtaggcact ggaggaatag accagaagcc tcgaacatta     3120

cccaggaaca ggacgttccc aattagaggc tttcagattt atgatgggcc cattcatctc     3180

acaaggagca ctttcaaaaa atatgtgcca actccagata ggtacagcag tgcaattggc     3240

ttcctcatga agaattcctg gcagataacc cccaggaata atatctccct cgtgaagttt     3300

ggtccacatg tctctctgaa tgtctttttt ggaaagcctg gtccctggtt tgaagattgt     3360

gagatggatg gtgataagaa ctccatattc catgacattg atggctctgt gacaggatac     3420

aaggatgctt atgtgggaag aatggacaac tacctgatcc gccatccaag ctgtgtaaat     3480

gtgtctaagt ggaatgcagt gatctgcagt gggacctatg cacaggtcta tgtacagaca     3540

tggagcactc agaatctttc tatgaccatt acacgagatg agtatccgtc caaccctatg     3600

gtgctccgag gtattaatca gaaggctgcc tttccacagt accagcctgt cgtcatgctg     3660

gagaagggtt ataccatcca ctggaatggg ccggcaccac ggactacatt tctatacctc     3720

gtcaacttca acaagaatga ctggattcga gttggccttt gctatccatc aaacacaagt     3780

tttcaagtta cctttggcta tttgcagcgg cagaatggct cattatccaa aatcgaagaa     3840

tatgagcctg tgcattcact ggaagaactg caaagaaagc aatccgagag gaaattctat     3900

tttgactcca gcacggggtt actgtttttg tatctcaaag ccaaaagcca caggcatggc     3960

cacagttact gttcatctca gggatgtgaa agagtcaaga tccaagcagc cacagactca     4020

aaggacatca gtaactgcat ggccaaagca tacccacagt actacagaaa gccgtcagtg     4080

gtcaagcgga tgccggccat gctcactgga ctctgtcaag gctgtggcac tcggcaggtg     4140

gtgtttacta gtgatcctca taaaagttac ctccctgtgc aattccagtc acctgataaa     4200

gcagaaaccc agcgtggaga cccgtctgtt atttctgtca atggcactga ctttaccttc     4260

cgaagtgcag gcgtcctcct ccttgttgtg gatccgtgca gcgttccatt ccgcttgacg     4320

gaaaaaacgg tttttcctct tgctgatgtc agtcgcattg aagagtattt aaaaacaggc     4380

atccctccaa ggtccattgt tctgttgagc acaagaggag aaataaagca gttaaacatt     4440

tcacacttac tagtacctct gggattagcc aaaccagctc atctttatga caaagggagt     4500

accatatttt tgggattcag tggaaacttt aaaccatcat ggactaagct atttaccagt     4560

cctgctggac agggccttgg ggtgcttgaa caattcatac ctttgcagct ggacgaatat     4620

ggttgtccca gagccaccac tgtccgcaga agagacctgg aactgctaaa gcaagcttca     4680

aaagcacatt agagactaac tgtaacttaa gtgctggggg aaaaaaaatg tgaactaact     4740

tatttaattt atggcatttt aaaatgacac tgttaaccca acggaaccat tttccagttt     4800

gatacagaat ggggagaaaa gaaagcgttt gaaattattg cttggatacc agcttcatgc     4860

accttctagt tgtacaaaat gttaaagacg ttgtttgtat ttgtaaggct ggtgtattca     4920

gagagcagat ctcttattcc tcactttcca cccccgtatt ttgtaatgac catgagcaat     4980

gtttttactt tttgtataat ggggtggggt ggagtggggg cttctgagag tcagcctgag     5040

gtctttagag gaccagctat tgtagcacct tggatacttg aagtttaatg ctcagttggg     5100

tcgggtggca gttgacttgg tggctggcat gttcagcagt gcctggggcc ctgtttctgg     5160

gcagcctttg aggattttct atgatattga atgacagttt taagtggcaa ctcaggccca     5220

gctcatgccc ttttttgcct ggacatgtgc tatttttatt cacttatata tcaattactt     5280

gtaagggtta aactttcaaa caggaagtat attgggacaa aagggctctt ggggattaga     5340

tatcccttta atctgtgacc attgggcaaa aaattttcct gcagcaaaag tctgaggctg     5400

ttgggaccat ttttgcagct ttaatcctta gcctcttttg actgtatatt tgtgtttaaa     5460

atgcagagct caactgaata tttccttttt tgttttgttt tgttttgttt taagaagtag     5520

gttgttttcc tgaaccgtaa acttgtatca ttttaacttg cacaaaggaa gtctgttctt     5580

ggtattgctc ttgcacttgg gttttttgtt attgttttgt gtggattttt taaagctttt     5640

ctgttcaccc tcctgccagg aaaatcccag aaagcttaat gataccccaa aatgattaca     5700

cccagggagg aaaaaaagga gcgctttcta gggtcagaat cgtggagaga atactcagaa     5760

atgaacctct ttaaagcctt gcaggaatga gtcactctta cttaatgaaa tgttaaagcc     5820

aattaaaaag catgctgtga tgcccagctt ccctttccac agggtgcatg cgtctcctgc     5880

tggtgaatca catgcggcaa gaggcaactg gctccacagc ctgggatgct gccgtaccaa     5940

gaggaaagaa gcagcaaaat gcctttacgt tgttctaaac ccccgacgca taaagtgtag     6000

aggagggatg gccaagggtg ggtggtagaa agtgtgttca ggctgacact ggcaatgagt     6060

acagataatt tcactttcct cttctagggg caaaggctga tggcctctac ctttgtatcc     6120

aggagaaact gcagagcagc cctgtgactt tacaaaatat gctacctcaa agtgctaccg     6180

ataaaccttt ctaattgtaa gtgcccttac taagggcaca tgtcttaatc aaagttagtt     6240

ttttgttttc tggtttgttt tttttttttg tatattgatg aatgagatct tacctattaa     6300

atatattatt ggattatggt tcctgaaggt cattagagtg tgtgtgtgtg tgtgtgtgtg     6360

tgtgtgtgtt ttatgactta aatatcttta cgtgtgtttt ttagagcttg gttctttaaa     6420

gatttggaga agatatgtaa attaccaagg cacttggttt ttctgtttta tatactaata     6480

atcagggcct aagttaaata aaaatatgtg tgcatgtatt ttaaaaaaaa aaaaaaaaaa     6540


<210>  2066
<211>  466
<212>  DNA
<213>  homo sapiens

<400>  2066
cttgccgcgc tgcactccac cacgcctcct ccaagtccca gcgaacccgc gtgcaacctg       60

tcccgactct agccgcctct tcagctcgcc atggatccca actgctcctg cgccgccggt      120

gactcctgca cctgcgccgg ctcctgcaaa tgcaaagagt gcaaatgcac ctcctgcaag      180

aaaagctgct gctcctgctg ccctgtgggc tgtgccaagt gtgcccaggg ctgcatctgc      240

aaaggggcgt cggacaagtg cagctgctgc gcctgatgct gggacagccc cgctcccaga      300

tgtaaagaac gcgacttcca caaacctgga ttttttatgt acaaccctga ccgtgaccgt      360

ttgctatatt cctttttcta tgaaataatg tgaatgataa taaaacagct ttgacttgaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                     466


<210>  2067
<211>  1383
<212>  DNA
<213>  homo sapiens

<400>  2067
aaagtccaag aggacggaat gtggagacag tgttgtattt ttgcggggag ttctaggccg       60

accgggagcg agagaacgct cgggggcgaa gcgcgccatt gcggccctcc ccgccgcctg      120

cggtagtcca gtcccaagat ggcggccacc atgaagaagg cggctgcaga agatgtcaat      180

gttactttcg aagatcaaca aaagataaac aaatttgcac ggaatacaag tagaatcaca      240

gagctgaagg aagaaataga agtaaaaaag aaacaactcc aaaacctaga agatgcttgt      300

gatgacatca tgcttgcaga tgatgattgc ttaatgatac cttatcaaat tggtgatgtc      360

ttcattagcc attctcaaga agaaacgcaa gaaatgttag aagaagcaaa gaaaaatttg      420

caagaagaaa ttgacgcctt agaatccaga gtggaatcaa ttcagcgagt gttagcagat      480

ttgaaagttc agttgtatgc aaaattcggg agcaacataa accttgaagc tgatgaaagt      540

taaacatttt ataatacttt ttttatttgt ttaataaact tgaatattgt ttaaaatgat      600

aattttcctt cttcaaatga catggaaagc aaaactttct tttttaaaaa ttttcattta      660

tttaatggaa acttgcccat tttcacatgt ctgcttattt attttatatt tttaaaagaa      720

gacagtattc acctatgtat tttgcataac gattatatca agtctagggg cttcatgtca      780

tgttattaaa atcagttaag caatctttta tgtttctata ttatttagaa tatttgttgt      840

tgcaattttc acataagaaa atttaacagt tgtgtcatgt tgtttctgtc tgattttaat      900

tgctgtctaa tgacggggaa agcacgatga aaagatgtac aatcctgcat ccttgcttat      960

ttcacaacta aagctttgtc atagacttca aaatatatat gtatatattt tatttaaata     1020

tatgttacat attatattta aacatacata tttaacattt tttacatatc tatcaatatc     1080

agagatttgg gtaaaagaat gggtaatgtt taaacatgtg gaggcatgtg gagctttata     1140

caaacagggc agaaccacag aagaacgttt tagaaaccaa gagatgtgca gaaagaaatg     1200

tttagtgttt tttcgtttta aattttagat tttattttag tgctttgtaa ttaattgggg     1260

tttatattga taaagatgtg gaagttaaac agctatgtat gtaaaagtaa ggcttatttc     1320

ttaaataaag gatgcatttc ttcccaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaa                                                                   1383


<210>  2068
<211>  11113
<212>  DNA
<213>  homo sapiens

<400>  2068
ggctccgggg gtggcggtcg gacagtgtct agcacgctca gtccgggctt ggggccccgc       60

ggcggagaag gaggtagagg gggcggcggc ggcggcggcg gtggtggcgg caccatgttt      120

cttcactcag ttaatctctg gaacctggcg ttttatgtct tcatggtctt tctggcaacc      180

ctggggctgt gggatgtctt cttcggcttc gaggagaata agtgcagtat gagctacatg      240

tttgagtacc cggagtatca gaaaatagaa cttccaaaga aactggcaaa acgctatccc      300

gcatatgagt tgtatcttta tggagaggga tcctatgctg aagaacacaa aattctccct      360

ttgacgggta ttccagttct ctttcttcct ggtaatgctg gaagttataa gcaagttcgt      420

tctattggct ccattgcact tagaaaagca gaggacattg acttcaagta ccactttgac      480

ttctttagtg tgaacttcaa tgaagaactg gtggctttgt atggtggaag tcttcagaag      540

cagaccaagt ttgtacatga atgtattaaa acaattctca aactctataa gggtcaagaa      600

tttgctccaa aaagtgtggc aataattggt cattctatgg gtggccttgt tgcaagagca      660

ttgcttacac tgaaaaattt taagcatgat ctgataaatc ttcttattac acaagccaca      720

cctcatgttg ctcctgtgat gccattagat cgtttcatta cagattttta tacgactgta      780

aacaactatt ggattctaaa tgctcgacac ataaatttaa ccacactttc tgtagctgga      840

ggattccggg attaccaagt tcgttcagga ttgacttttc taccaaaatt aagccatcat      900

accagtgcct tatctgttgt gagttcagca gtgcctaaga cctgggtctc aacagaccac      960

ctctccattg tgtggtgtaa acaattgcag ttgactacag ttcgagcatt ctttgatctt     1020

attgatgctg atactaaaca aataactcaa aattccaaga agaaactgtc agttttgtat     1080

caccacttta taagacaccc atcaaaacat tttgaggaaa atccagctat aatttctgac     1140

ttaacaggga catctatgtg ggttctagta aaagtgtcca aatggaccta tgtagcttac     1200

aacgaatctg agaagatata ttttacattt cctcttgaaa atcatagaaa aatctacact     1260

catgtctatt gtcagagcac tatgctggat acaaatagtt ggatttttgc ttgcataaac     1320

agcacttcta tgtgcctgca aggggttgat ttatcatgga aagctgaact gctgccaaca     1380

attaagtatc tgacattaag acttcaagac tatccatctt tgtctcatct tgttgtttat     1440

gtaccatctg ttcgtggaag taagtttgtt gtagattgtg aattctttaa aaaagagaaa     1500

agatacatac agcttcctgt aactcatctt ttttcctttg gattgtcttc aaggaaagtg     1560

gtgttaaata caaatggcct atactacaat ctagagcttc tgaactttgg acagatatac     1620

caagctttta aaatcaacgt ggtaagcaag tgctcagcag tcaaagaaga aataaccagt     1680

atctatagac ttcatattcc ttggtcttat gaagattcac taaccattgc acaggctcca     1740

tcttccacag aaatttctct gaaactccat attgctcaac cagaaaacaa tacccatgtg     1800

gcattattta aaatgtacac gtcatcagac tgtcggtacg aggtgacagt taagacttcc     1860

ttttcacaaa tacttggaca ggtagttaga tttcatggtg gagctcttcc tgcttatgtc     1920

gtatctaata tccttcttgc ttatagagga cagttatatt ctcttttctc aacaggttgt     1980

tgcttagaat atgctaccat gttggataaa gaagccaaac catacaaagt tgatcctttt     2040

gtaattatca ttaagtttct gttggggtat aaatggttta aagaattgtg ggatgtatta     2100

ttgttaccag aattagatgc cgtcatttta acttgtcaga gtatgtgttt ccccctgata     2160

tccttgattc tctttctgtt tggaacgtgt actgcctact ggagtggcct actgtcttct     2220

gcatctgtga gacttctttc ttcattgtgg ctagctttga aaagaccctc tgaacttcct     2280

aaagatatca agatgatatc accagacttg ccctttttga caattgtctt gatcatagtt     2340

agttggacaa cttgtggagc actagccata cttctttctt atctttacta tgtgtttaag     2400

gttgttcatc tgcaagccag cttaacaact tttaagaata gccagcctgt gaatcccaaa     2460

cactctagaa gaagtgaaaa gaaatccaat catcataaag actcctcaat acaccatctt     2520

cgtttatctg ccaacgatgc tgaagatagc cttcgcatgc acagtactgt gattaactta     2580

ctaacatgga ttgtattact cagcatgcct tctctaattt attggctaaa gaatcttagg     2640

tattatttta aacttaatcc tgatccatgt aaacctttgg catttatcct tattccgact     2700

atggcaattc ttggaaatac ttacactgtt tcaataaaat caagtaaatt gttgaagact     2760

acttcacaat ttccacttcc tctggctgtt ggtgtgattg cttttgggtc agcacattta     2820

tataggcttc catgctttgt cttcattcct cttttactcc atgcattatg caactttatg     2880

taagattgga cttaaggaat gatgaagata atttatgtgt ttagggccag tgataagagg     2940

gaacacacag atccatcagt atggacagca agatcctttg gagaagacaa gtctattttt     3000

acaatattga aaataggaaa ttagttttgt aatgtttgag ggaagtagtt gaagcatggt     3060

tttgttttgt ggtgtggaat ccatgtagta atcatttttg aaaaattcat gaagggatat     3120

atggtgatca ctatcattga ggactcctgt gcatataaaa tagtctgttt tatcaactgt     3180

acgagaagtc tgatatgaga gatttagtag atgcagcatt atttgcagtc tcactgcaag     3240

cattctgctc atttcatcaa actttttttc acaaaagtag gttattttga atttgctata     3300

gtttacctat taagaaataa gtctttaaat aactgatgaa atttatagct gtttggtttc     3360

tcaaaggtta aatagccaca gaaagccttt ggttagtttt tggcagccac catgaacaaa     3420

gtggatcttg tcttcttaca tctatgaaaa tagagctttg aatggtaagg agatatgttt     3480

tcttggtaac caatgcaaga ttgatgggtg gaaacatgat tcaaacttac acaatttttc     3540

ttgctatttt tcaaatatga atcttactat atattctcgg tgaacatcag gagactatta     3600

aagaggtctg ctgttaaatg taaagaaaaa atgctcgtag ctatttgctt cctggtattg     3660

gagcagttca gttgtttagt ttataccatt ggattcaatt cattgcacca tggttgccaa     3720

aagtgcctga ggtcataatg gattgttaaa ataactaaat tccagtggtt ggaaactcta     3780

ggtttgtacc attttttctg ctgtgggaaa aaacaacaac aacaacatga tcaaggtaac     3840

atcacatttg atgtataata ttatactatt aatggaatat cagtagacaa ctgttaaccc     3900

attagtagca tgagtataaa cagtacacct gaataaattg gagacattag ccactaggtt     3960

taacagtgga atcttgattt gcctaggtga cttctgggat tactgtttga caaataagag     4020

taacatttta tttcatttca gaatttacgt cacttttagc tacaagagta ggaagaaggt     4080

aatcggcaag gcagaagagt atactctttg ccttaggata gcgtaaactc aggctgagac     4140

atacccggct tatagagttc ttctagatgt gtagactgta aatgcccaaa tcctctcaac     4200

taaagtttta gtgattccac aaagcctctc atgtaaattt ccagtgattc caccattgca     4260

cttgtgaata tgtatccttg ttagtaccca gggatgtcct cgagcaccag ttttatttta     4320

tctgccattg catctggatt ccattacagc ctctcagctg ttactgcctg tggacagtta     4380

cttctgctta ctgcctgtag agagttacct aacttctctt ctcagttctt cctcaggtcc     4440

tggctatttt ggcctcagtt gaagggagtc ttgctctcat ctctgagggt tttaagtttg     4500

tttgatccca ttgttgtctt ttctagcttt gagcatgttt ttcagtattc atattttaac     4560

ttactgagaa cattaaaggg aaatgataaa ctcgtggtgg ggatatggca gacaggtgct     4620

tgtttgtttg agagaagtag cagaagagat aaaatacaaa gtgctatatg tttcagctgg     4680

agaggaaaga gagagaattt attagattat atacttgtcc catggcatac cacgtatatg     4740

tttaaatagg gacacatctc cctatgttta actatactta taaacaactt tgatacacat     4800

tgcgtctttt attctgtcac ctgatatttt agtgtatctc aagttacaga ttacatgtgt     4860

ccttaaacta tttctgaatt tggacttagt tccatataca gaaagaactt tagaaaattc     4920

attaatttgg atcttctatt gatagccata aatattatgt ttatgtattc taaaacctct     4980

ttgtttagtt agtactgttc atgaatgtaa caagcttcaa tttctcattt gtgagtagta     5040

catttgcttt ttgtttgttt gtttgtttgt ttttgagatg gagtctcacg ctgtcaccag     5100

gctggagtgc agtggcgcga tttcagctca ctgcaacctc cacctcccag gtgcaagtga     5160

tgcccctgcc tcagcctccc gagtagctgg gactacagac acccgccacc acacctggct     5220

aatttttgta tttttagtag agacggggtt tcaccatgtt ggctaggctg gtctcaaact     5280

cttgacctcg tgatttgccc gcctctgcct ccccaaagtg ctgggattac aggcgtgagc     5340

caccacgccc agccgtacat ttacttttta aagcagcaga ctaggtacac taattctcac     5400

tcaaatattt tcatgggaat gtagttatca ccaagtccta aagtattatt tatgccaaaa     5460

aaaatttcat tttaaggact acaaaaatga ttctaattaa acattttata atcaatagta     5520

ggttgggtct ttagccatta tatgtgtata tatacagaca catatgtata cacttacatt     5580

ttgacagggt cttcattgag tcttgatgca ctttaaaccc agctggctac cagagatgcg     5640

aaggtgggct ctttgaagat tagcaaaatg gacgtttctg tcacttgaga aaaggaaagt     5700

tctttgcctt taaattacac agttttcatc atgcccacaa tctatattat tggctggtta     5760

aacagcactg ccctattagc aatgttaaca aaaatgaaat tatttattgg cggttataga     5820

ttatctaatt caggaaattt ctgagctcaa cttttacagc aactgttatg ccttctaatt     5880

tagcaattga gttatgagta agttttgtgc ttaactccta gaccctattg ttgataacca     5940

gatcaaatat agtctgtaca gaggaaaaca ctgggaacat ttagtatttc taaagcctcc     6000

tttggagtta ctactgattg taatttggaa ctgataatag gtagagattg ctaacactgt     6060

tttttttcct ggatcttttt tatgccagaa attaaacagg ttctgctaac tctttttttt     6120

ctcttggtta tcaccagaat gaaaatattt aaagtgatga ctctagaaaa gccatctgtg     6180

cctggttaac attgagtttg agtctcttca atatatattg atcatgtatt gattaatctt     6240

tattttttca tattttggct agacaaattc agatctatat aatggaatac cccttcttga     6300

gtgaactata ctactaatct acatgattat atagtaagga aaaaagaaga aataactgta     6360

ataggcatag tgtttgttgt tggttgtctt gtcattcatg tgatactact catttccaaa     6420

attcacacaa acttacatga ggtggattat ttgttttgtt cattatttag ttcctatatg     6480

ttttttcttt agaaacagag tctcattctg tcacccaggc tggagtccaa tggggcggtc     6540

atagttcact gcagccttga actctttggc tcatgtgatc ctcccatctc agcctcccac     6600

agcaggtgag actacaggta catgccactg tgcctgactt tttaattttt ttgtagagac     6660

gaggtttcag tttgttgccc aagctgatct tgaactcctg gtttcaagcg atcctcccac     6720

ctcggcctcc caaagtagtg ggatttcagg catgaccacc tggcctagtt cctatacttt     6780

tcttaattct tcagacttct cacatttagt atagtgcatt catttcatct tgctgtttat     6840

tagcaccctt tgtggccaag ggaaataaaa ggtggtaaaa ttcagttttc agtttagttc     6900

ttgaaagctc tgggaaatgg aggaaacaca aaactatgaa ttaaactagg gctgttgatt     6960

tctgaacccc cagataaatc agttgaccca cattttcatt ttaggtgtta ggtccaaatt     7020

agcataatgt cttgcattat tattaggttc agtgtgaaac tttacagtgc tgcatttgaa     7080

gtttagtaac tggttattat taatcatttg ggaaaaatga aaatgtgttg ggactttcta     7140

tgactaggca tttgttgatt atttttcatg attgcttttt gttttctcat tgtgtaggat     7200

ttgtgaactt gtatattaca ggaaacaaga tactttgtaa aatttactgg ggaaaatcca     7260

tttggagtgc atgacatttg ccaggataag aaagcagtaa tatgtttgta ttataaaatt     7320

acaccctgcc agaaaacttt ctttcctagt aaggtaaatg tagaagggac ttttacagca     7380

tagtaagttg attaggagcc aaaattttat tccagttttt ttttgaacta agaatgtttt     7440

aaattctgta atgaactttt atgtttaccc attactcatg cattctttca caatatgttt     7500

aatagcctga ggaaatagga aagctgtgaa gctactacca ttctttactt ttaataagaa     7560

taataggaaa gaaaagtcag gtcagtaatc caaatccaaa tatgtatact gcaaatgctc     7620

aagaagtcac attttttgat aaattgtatt gagtacagaa gaacttatat gaatttatta     7680

tctgttaata acttagtttt gacaacagaa taacatttgg aaattgtgag aataatcaag     7740

ctgtttttcc attaacagtg taaattcata acatgtcctt caaaaggtga tattctaagc     7800

tgtcttaatt gtctacggtt gataactttt aaataaagta caggactttc tgaaagtgtt     7860

tggcatgtta tgctgccaaa aacaatctgt gttttgaaat accaattaat cagttaattt     7920

ctgaagactt tgtataggac ttgatatatg agtcagaatc tgtctgtact cattctgtac     7980

attgtaactt tgaacactta tgaaaaactg tatctgttgg tgtgttttga ttagttagtg     8040

tagatttgtt tgcgtatttg aattccgatt ttagtttagg aagactaaaa gtagccattt     8100

ttgtaaagtt catatgctat tttttaatgt catttttgtt tttaatattt atacaatagt     8160

gatgttacta gtaaaaaatg tttatagata acacgtagag ctattaactg ttcaaaagcc     8220

tacatgatag gcatattttg tatttcgtgt tgcactcgtt ctgtttcata ttggactttt     8280

tacatccctt ttttagcaaa aaaaagagac acatttgaat tctctttagc ataaagctgt     8340

gcattggaaa ctatgtgact gtatccatac ggttagcaaa atactctttg ccaccaaagg     8400

taaatgaaac tgtaaaatac ctctggatat ttgtgccaat gaacttttct tagcatatta     8460

ggattaaagc aaaaataatc ttttcagtat gtttcatcta ggacttacaa taaatgttta     8520

aaccatgaaa acttatattt cataccctaa tttttctttg aaaatattca agatttgtag     8580

cctagtgtgt tctattttgt gtgattgctt gaatgttttc tgattttatt gggtaaaagt     8640

ttgcctagta atgatctttc agcaattcat tgaaataatt atttgaagta atcttgcttc     8700

agatttaatt tgtgatgtac attgttgtac aagccatttt agtacaggtg tctcatttat     8760

gtagttgaaa ggtgactgtg gaatttcttt tgttttttat gtatttccat tcagtctctt     8820

tatatagtca catgtttcac aggggaactt gtccactgga acctaacata gtacaacctt     8880

ttaatatgcg tatcttaaag gaaaatatta taaaacaaga tattaatact aaagtgttaa     8940

cattaatatg ttgttctcat ggaagaaaag tagaaaatgt gataggctta gaaattattt     9000

tttatcagca ttaagtgctt caatttctcc ccataaagat tctaaggaaa tttcagttcc     9060

tcatattata gttttcccca taatttaata ttactaagta tttctctgcc cagtaatgtt     9120

gatgcagttt gcataaatag ccttggaagt aaggaggcag gacagaaagc caaatatcga     9180

aatctctggc cttgatttag tgacagttta ttctaatggg gaccataggt gttattagta     9240

aaaagatagt gtacaaggcc taagttcagt ttacattgtt ctttgaaatg agttcatctt     9300

ttgtgttgaa taattgtatt ctaagtagga gatgcctgta tttaacataa tcatgctttc     9360

tatataatca aatatgtatt tgttggaata ctggtagaaa taaccttccc ttcctccact     9420

gtgcagtgga aaaaaaactc ccgatttata ctgtatataa attaggaaat tatgttacat     9480

atttacattt ttaaaaatat aaaaatgaca tattattttg aagtgattgt attatagttt     9540

ctgaagctta tgactggcta taaatataac aacataccca tgagaaacca gaccaaaatt     9600

gaatatatat catcactgtg accttgaact tatagtcatt tgggataaaa cagagtgtgc     9660

cttgaaatga taaagagtgc cctgcaattt tataactgta cattttatta tgggtggtcc     9720

tctcaaattg gccccaaatc cttgtcttcg aggttggtga aataaaagtt taaaataaaa     9780

gttgactggt atttccttta gtatttccag aactattgct gtagaggcct cccttaattt     9840

tcagagttct cattttgaat taaagtagac ttacgctaca tagatgtaga aaattaggtt     9900

tggcttaggt ttctgaaaaa atattctagg agaaggtggt agcattgttc tgaacttacc     9960

acacttggaa aaactaatct tcaaatgtaa ttttttgtct tattaatgag taatctgtca    10020

aagacatgaa ttctttgact tgtgctcatt ctttctgaac ttattgaggc ttatatatat    10080

caaataaggt taatttacac aataattatt tttaataatt aataaactca ttcatgtagt    10140

atattttaaa acattatttc ctctcatttt tccttctctt ttttcttcct atatattttt    10200

aaggcttcaa gagaaaacgg gcttcagttt ttaaaaaaat gtagacttgc atttttactg    10260

tgcttattta aaataatgga tataatttat attaaggtcc aaattatttt attcacagga    10320

taatcatggt ctctgataaa agatgcccac atttctgtgt actcacagtt gttgtatatt    10380

tttcaatttc aattttgaaa gtaaactcaa cacattgttt tcccatttta cctccactac    10440

ctactcgcca gacaaaaata tagatttctc taaaaacaca tacaaagaaa atgtctttcc    10500

ttaaaacatg atcttattga catgaaggta gtttgagcaa gggtatgtaa taaaataaat    10560

ggctctcaac ctgcatcaat ttttatacta tagttaaaaa atttatagag gacaacctat    10620

gtgttatgct gagatagact cagtaatcat ttgtttgcaa attgattatt tttttctcat    10680

ccatccagaa agtacagtgc ataacaacaa cacttaacaa gtgcagagga acctgtcctg    10740

tagtatataa taaaaaatga ttgtcacctt gctgatcttt ccatttaaac atgcatgatc    10800

tccagtactt tgtacaatgt atagtatatt aaatacattt atgtgtaatt ttgtgtgtat    10860

ttttatatgg tataattaaa attattacat ttatgtgatt gtaattcaca aaaagtacta    10920

cttactatat tctgtagagt gtgttgtgaa tgtttttacc tgtgtttgag cattatggtg    10980

taggtttaat agatgaatat ttgccttcag tctctgctca ggtattaatg tgtagtaatt    11040

tttggtgctt tctttttaat ctgtgataat ctggtgttct gaatgttcaa aaataaattt    11100

ggttgaatac gca                                                       11113


<210>  2069
<211>  2793
<212>  DNA
<213>  homo sapiens

<400>  2069
agtgcttctg gtttcagcac acatggagat atagaattga aattgctctg ctttctttac       60

aaatgactca gagtgtgctt gtccttccct aaaatgttgc cagcatgtaa aggattttca      120

atgagcagtg caataagcca gcaactggga aggcttggag cggcactgat ataacgtggt      180

gctgtcacac agataatcag ggctggagcc aagtctcggt agcgctgtgc attatcctgg      240

tcacatactg gaagttttgt ttatccaact tggttgctct tgaagctggt gagagccctg      300

ccaggatgtg gagtggactt cctagcagag gcagtacatg ccacactact acccttcctg      360

ctcttgtgcg cacacctacc ctgatgatgc agccttcact ggatatcaaa ccatttatgt      420

cttttccagt ggacagtagt tctgctgttg ggctctttcc aaattttaac acaatggatc      480

ctgtgcaaaa agcggttatt aaccatacat ttggagtatc cattccccca aagaagaaac      540

aagttatttc ttgtaatgtc tgtcagcttc gctttaactc agatagccag gccgaggccc      600

actacaaagg aagtaaacat gccaagaagg tcaaagcact agacgcaacg aaaaataaac      660

ccaaaatggt tccttccaag gacagcgcaa aggctaatcc cagctgctcc atcactccaa      720

tcacaggcaa caactctgac aaatcagaag ataaagggaa gttaaaagcc agcagttcca      780

gtcagccatc aagctctgaa agtggctcat ttctcctcaa atctggcaca acacccctgc      840

cacctggagc agccacttct ccctccaaga gcacaaatgg agctcccggt actgttgttg      900

aatcagaaga agaaaaagcc aaaaaattac tttattgttc actatgcaaa gtggctgtga      960

actccctgtc acagctagag gcacacaaca caggatctaa acacaagacc atggttgaag     1020

ctcgtaatgg ggctggtcca attaaatcct atcctagacc tggatcaaga ttaaagatgc     1080

agaatggcag taaggggtca ggactacaga acaagacatt tcattgtgaa atctgtgatg     1140

ttcatgttaa ttcagaaatt caactcaaac agcacatttc tagccgaagg cataaagatc     1200

gagttgcagg gaaaccactg aagccaaaat acagccctta caacaaactc cagcggagcc     1260

cgagtattct agcagcaaaa cttgcattcc agaaagatat gatgaagcct ttggccccag     1320

ccttcctgtc ctcacctctc gcagcggcgg cagccgtgtc ctcagcgctg tcactcccac     1380

cccggccctc tgcctcgctc ttccaggctc cagccattcc tccagctctt ctgaggcctg     1440

ggcatgggcc catccgcgcc actcctgcct ccatcctctt tgctccgtac taacgtctgc     1500

aaaccccaag acgtttgagg ccagtaggaa gttgagaaag aaagccacaa ggattcagca     1560

atttaagcag tttgtgttgc agtacccccc attcacccac aaaatgcagc ccaccaccca     1620

gtcccccaat tccagagaga aacacatcac tagattgacg agggctttta gagactgctc     1680

ctataattga ggaatcagca gcataggctt tatctcccta cttcctcccc caccctaccg     1740

cgttcaattt gtgtatctca gatatttgat ttcttgagca tgtattggtc agaaagaaaa     1800

agaaagaaaa ccattctcta tttttccatg ggtatgatct ggcttaaaac aatatggaat     1860

attttcctga cagacttgaa aactaggatc ttcctcagat gtctgtaaat aactctggta     1920

tccaactggg tgtattctag tgtggaacaa aaaacagtga acacaagtgc ttacttgtgg     1980

atactatctt accaacggat cacaaagttc tctttttggt gtactgttgt tgacagggat     2040

tgtgtactgt ttcgacccaa gtactgctgt atcctgtgta gtactagatc tgtatctctt     2100

gtctgaatta aacattttta gttgctgtgt aaatgttagg aagcaaagta gctttgaatt     2160

ttctctgtaa gagaataaaa gataaaataa tgtattttct ttatttcaca ttttatttgg     2220

agatatttaa atgaaataga aagccatata acatagctat aattactacc tgtttgctat     2280

ttttgtttaa cttattttgt agcttcctca ctggtttgtg ttgctaagca aacgtataca     2340

aacagaaaaa gagcttccta aattgcacat ttttgcacct cttgtgcatt ctgcaagaag     2400

acaatgaatc catgtatttc tatataagta tcttcttcat ttttaacctg ttttcatttg     2460

taatgatgct acataatttt gtggctccct aatgcaataa tgtacagaag ataaaaaaat     2520

ttataattga acaatttgtc tttctgttcg ctgaatatat tgcaggtcat gctcccatgc     2580

ccccctttct aagccgatat caacaagact ggaatgtttg tgatatcagg ggcaagagtt     2640

atcatagaac aacaaaatag agtggactct tttagagcat ctatatctgc aacctgtaaa     2700

tggtaaaatg tctgtgtatt tttttaaatg taccttttca ataaaagtac aaaaaataaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa                                  2793


<210>  2070
<211>  9609
<212>  DNA
<213>  homo sapiens

<400>  2070
atggcccata acgcgggcgc cgcggccgcc gccggcaccc acagcgccaa gagcggcggc       60

tccgaggcgg ctctcaagga gggtggaagc gccgccgcgc tgtcctcctc ctcctcctcc      120

tccgcggcgg cagcggcggc atcctcttcc tcctcgtcgg gcccgggctc ggccatggag      180

acggggctgc tccccaacca caaactgaaa accgttggcg aagcccccgc cgcgccgccc      240

caccagcagc accaccacca ccaccatgcc caccaccacc accaccatgc ccaccacctc      300

caccaccacc acgcactaca gcagcagcta aaccagttcc agcagcagca gcagcagcag      360

caacagcagc agcagcagca gcagcaacag caacatccca tttccaacaa caacagcttg      420

ggcggcgcgg gcggcggcgc gcctcagccc ggccccgaca tggagcagcc gcaacatgga      480

ggcgccaagg acagtgctgc gggcggccag gccgaccccc cgggcccgcc gctgctgagc      540

aagccgggcg acgaggacga cgcgccgccc aagatggggg agccggcggg cggccgctac      600

gagcacccgg gcttgggcgc cctgggcacg cagcagccgc cggtcgccgt gcccgggggc      660

ggcggcggcc cggcggccgt cccggagttt aataattact atggcagcgc tgcccctgcg      720

agcggcggcc ccggcggccg cgctgggcct tgctttgatc aacatggcgg acaacaaagc      780

cccgggatgg ggatgatgca ctccgcctcc gccgccgccg ccggggcccc cggcagcatg      840

gaccccctgc agaactccca cgaagggtac cccaacagcc agtgcaacca ttatccgggc      900

tacagccggc ccggcgcggg cggcggcggc ggcggcggcg gcggaggagg aggaggcagc      960

ggaggaggag gaggaggagg aggagcagga gcaggaggag caggagcggg agctgtggcg     1020

gcggcggccg cggcggcggc ggcagcagca ggaggcggcg gcggcggcgg ctatgggggc     1080

tcgtccgcgg ggtacggggt gctgagctcc ccccggcagc agggcggcgg catgatgatg     1140

ggccccgggg gcggcggggc cgcgagcctc agcaaggcgg ccgccggctc ggcggcgggg     1200

ggcttccagc gcttcgccgg ccagaaccag cacccgtcgg gggccacccc gaccctcaat     1260

cagctgctca cctcgcccag ccccatgatg cggagctacg gcggcagcta ccccgagtac     1320

agcagcccca gcgcgccgcc gccgccgccg tcgcagcccc agtcccaggc ggcggcggcg     1380

ggggcggcgg cgggcggcca gcaggcggcc gcgggcatgg gcttgggcaa ggacatgggc     1440

gcccagtacg ccgctgccag cccggcctgg gcggccgcgc aacaaaggag tcacccggcg     1500

atgagccccg gcacccccgg accgaccatg ggcagatccc agggcagccc aatggatcca     1560

atggtgatga agagacctca gttgtatggc atgggcagta accctcattc tcagcctcag     1620

cagagcagtc cgtacccagg aggttcctat ggccctccag gcccacagcg gtatccaatt     1680

ggcatccagg gtcggactcc cggggccatg gccggaatgc agtaccctca gcagcagatg     1740

ccacctcagt atggacagca aggtgtgagt ggttactgcc agcagggcca acagccatat     1800

tacagccagc agccgcagcc cccgcacctc ccaccccagg cgcagtatct gccgtcccag     1860

tcccagcaga ggtaccagcc gcagcaggac atgtctcagg aaggctatgg aactagatct     1920

caacctcctc tggcccccgg aaaacctaac catgaagact tgaacttaat acagcaagaa     1980

agaccatcaa gtttaccaga tctgtctggc tccattgatg acctccccac gggaacggaa     2040

gcaactttga gctcagcagt cagtgcatcc gggtccacga gcagccaagg ggatcagagc     2100

aacccggcgc agtcgccttt ctccccacat gcgtcccctc atctctccag catcccgggg     2160

ggcccatctc cctctcctgt tggctctcct gtaggaagca accagtctcg atctggccca     2220

atctctcctg caagtatccc aggtagtcag atgcctccgc agccacccgg gagccagtca     2280

gaatccagtt cccatcccgc cttgagccag tcaccaatgc cacaggaaag aggttttatg     2340

gcaggcacac aaagaaaccc tcagatggct cagtatggac ctcaacagac aggaccatcc     2400

atgtcgcctc atccttctcc tgggggccag atgcatgctg gaatcagtag ctttcagcag     2460

agtaactcaa gtgggactta cggtccacag atgagccagt atggaccaca aggtaactac     2520

tccagacccc cagcgtatag tggggtgccc agtgcaagct acagcggccc agggcccggt     2580

atgggtatca gtgccaacaa ccagatgcat ggacaagggc caagccagcc atgtggtgct     2640

gtgcccctgg gacgaatgcc atcagctggg atgcagaaca gaccatttcc tggaaatatg     2700

agcagcatga cccccagttc tcctggcatg tctcagcagg gagggccagg aatggggccg     2760

ccaatgccaa ctgtgaaccg taaggcacag gaggcagccg cagcagtgat gcaggctgct     2820

gcgaactcag cacaaagcag gcaaggcagt ttccccggca tgaaccagag tggacttatg     2880

gcttccagct ctccctacag ccagcccatg aacaacagct ctagcctgat gaacacgcag     2940

gcgccgccct acagcatggc gcccgccatg gtgaacagct cggcagcatc tgtgggtctt     3000

gcagatatga tgtctcctgg tgaatccaaa ctgcccctgc ctctcaaagc agacggcaaa     3060

gaagaaggca ctccacagcc cgagagcaag tcaaagaagt ccagctcctc caccactact     3120

ggggagaaga tcacgaaggt gtacgagctg gggaatgagc cagagagaaa gctctgggtc     3180

gaccgatacc tcaccttcat ggaagagaga ggctctcctg tctcaagtct gcctgccgtg     3240

ggcaagaagc ccctggacct gttccgactc tacgtctgcg tcaaagagat cgggggtttg     3300

gcccaggtta ataaaaacaa gaagtggcgt gagctggcaa ccaacctaaa cgttggcacc     3360

tcaagcagtg cagcgagctc cctgaaaaag cagtatattc agtacctgtt tgcctttgag     3420

tgcaagatcg aacgtgggga ggagcccccg ccggaagtct tcagcaccgg ggacaccaaa     3480

aagcagccca agctccagcc gccatctcct gctaactcgg gatccttgca aggcccacag     3540

accccccagt caactggcag caattccatg gcagaggttc caggtgacct gaagccacct     3600

accccagcct ccacccctca cggccagatg actccaatgc aaggtggaag aagcagtaca     3660

atcagtgtgc acgacccatt ctcagatgtg agtgattcat ccttcccgaa acggaactcc     3720

atgactccaa acgcccccta ccagcagggc atgagcatgc ccgatgtgat gggcaggatg     3780

ccctatgagc ccaacaagga cccctttggg ggaatgagaa aagtgcctgg aagcagcgag     3840

ccctttatga cgcaaggaca gatgcccaac agcagcatgc aggacatgta caaccaaagt     3900

ccctccggag caatgtctaa cctgggcatg gggcagcgcc agcagtttcc ctatggagcc     3960

agttacgacc gaaggcatga accttatggg cagcagtatc caggccaagg ccctccctcg     4020

ggacagccgc cgtatggagg gcaccagccc ggcctgtacc cacagcagcc gaattacaaa     4080

cgccatatgg acggcatgta cgggccccca gccaagcgcc acgagggcga catgtacaac     4140

atgcagtaca gcagccagca gcaggagatg tacaaccagt atggaggctc ctactcgggc     4200

ccggaccgca ggcccatcca gggccagtac ccgtatccct acagcaggga gaggatgcag     4260

ggcccggggc agatccagac acacggaatc ccgcctcaga tgatgggcgg cccgctgcag     4320

tcgtcctcca gtgaggggcc tcagcagaat atgtgggcag cacgcaatga tatgccttat     4380

ccctaccaga acaggcaggg ccctggcggc cctacacagg cgccccctta cccaggcatg     4440

aaccgcacag acgatatgat ggtacccgat cagaggataa atcatgagag ccagtggcct     4500

tctcacgtca gccagcgtca gccttatatg tcgtcctcag cctccatgca gcccatcaca     4560

cgcccaccac agccgtccta ccagacgcca ccgtcactgc caaatcacat ctccagggcg     4620

cccagcccag cgtccttcca gcgctccctg gagaaccgca tgtctccaag caagtctcct     4680

tttctgccgt ctatgaagat gcagaaggtc atgcccacgg tccccacatc ccaggtcacc     4740

gggccaccac cccaaccacc cccaatcaga agggagatca cctttcctcc tggctcagta     4800

gaagcatcac aaccagtctt gaaacaaagg cgaaagatta cctccaaaga tatcgttact     4860

cctgaggcgt ggcgtgtgat gatgtccctt aaatcaggtc ttttggctga gagtacgtgg     4920

gctttggaca ctattaatat tcttctgtat gatgacagca ctgttgctac tttcaatctc     4980

tcccagttgt ctggatttct cgaactttta gtcgagtact ttagaaaatg cctgattgac     5040

atttttggaa ttcttatgga atatgaagtg ggagacccca gccaaaaagc acttgatcac     5100

aacgcagcaa ggaaggatga cagccagtcc ttggcagacg attctgggaa agaggaggaa     5160

gatgctgaat gtattgatga cgacgaggaa gacgaggagg atgaggagga agacagcgag     5220

aagacagaaa gcgatgaaaa gagcagcatc gctctgactg ccccggacgc cgctgcagac     5280

ccaaaggaga agcccaagca agccagtaag ttcgacaagc tgccaataaa gatagtcaaa     5340

aagaacaacc tgtttgttgt tgaccgatct gacaagttgg ggcgtgtgca ggagttcaat     5400

agtggccttc tgcactggca gctcggcggg ggtgacacca ccgagcacat tcagactcac     5460

tttgagagca agatggaaat tcctcctcgc aggcgcccac ctcccccctt aagctccgca     5520

ggtagaaaga aagagcaaga aggcaaaggc gactctgaag agcagcaaga gaaaagcatc     5580

atagcaacca tcgatgacgt cctctctgct cggccagggg cattgcctga agacgcaaac     5640

cctgggcccc agaccgaaag cagtaagttt ccctttggta tccagcaagc caaaagtcac     5700

cggaacatca agctgctgga ggacgagccc aggagccgag acgagactcc tctgtgtacc     5760

atcgcgcact ggcaggactc gctggctaag cgatgcatct gtgtgtccaa tattgtccgt     5820

agcttgtcat tcgtgcctgg caatgatgcc gaaatgtcca aacatccagg cctggtgctg     5880

atcctgggga agctgattct tcttcaccac gagcatccag agagaaagcg agcaccgcag     5940

acctatgaga aagaggagga tgaggacaag ggggtggcct gcagcaaaga tgagtggtgg     6000

tgggactgcc tcgaggtctt gagggataac acgttggtca cgttggccaa catttccggg     6060

cagctagact tgtctgctta cacggaaagc atctgcttgc caattttgga tggcttgctg     6120

cactggatgg tgtgcccgtc tgcagaggca caagatccct ttccaactgt gggacccaac     6180

tcggtcctgt cgcctcagag acttgtgctg gagaccctct gtaaactcag tatccaggac     6240

aataatgtgg acctgatctt ggccactcct ccatttagtc gtcaggagaa attctatgct     6300

acattagtta ggtacgttgg ggatcgcaaa aacccagtct gtcgagaaat gtccatggcg     6360

cttttatcga accttgccca aggggacgca ctagcagcaa gggccatagc tgtgcagaaa     6420

ggaagcattg gaaacttgat aagcttccta gaggatgggg tcacgatggc ccagtaccag     6480

cagagccagc acaacctcat gcacatgcag cccccgcccc tggaaccacc tagcgtagac     6540

atgatgtgca gggcggccaa ggctttgcta gccatggcca gagtggacga aaaccgctcg     6600

gaattccttt tgcacgaggg ccggttgctg gatatctcga tatcagctgt cctgaactct     6660

ctggttgcat ctgtcatctg tgatgtactg tttcagattg ggcagttatg acataagtga     6720

gaaggcaagc atgtgtgagt gaagattaga gggtcacata taactggctg ttttctgttc     6780

ttgtttatcc agcgtaggaa gaaggaaaag aaaatctttg ctcctctgcc ccattcacta     6840

tttaccaatt gggaattaaa gaaataatta atttgaacag ttatgaaatt aatatttgct     6900

gtctgtgtgt ataagtacat cctttggggt tttttttttc tctttttttt aaccaaagtt     6960

gctgtctagt gcattcaaag gtcacttttt gttcttcaca gatcttttta atgttctttc     7020

ccatgttgta ttgcattttt gggggaagca aattgacttt aaagaaaaaa gttgtggcaa     7080

aagatgctaa gatgcgaaaa tttcaccaca ctgagtcaaa aaggtgaaaa attatccatt     7140

tcctatgcgt tttactcctc agagaatgaa aaaaactgca tcccatcacc caaagttctg     7200

tgcaatagaa atttctacag atacaggtat aggggctcaa ggaggtatgt cggtcagtag     7260

tcaaaactat gaaatgatac tggtttctcc acaggaatat ggttccatta ggctgggagc     7320

aaaaacaatg ttttttaaga ttgagaatac atacctgaca acgatccgga aactgctcct     7380

caccactccc gtcatgcctg ctgtcggcgt ttgaccttcc acgtgacagt tcttcacaat     7440

tcctttcatc attttttaaa tatttttttt actgcctatg ggctgtgatg tatatagaag     7500

ttgtacatta aacataccct catttttttc ttttcttttt tttttttttt tttagtacaa     7560

agttttagtt tctttttcat gatgtggtaa ctacgaagtg atggtagatt taaataattt     7620

tttattttta ttttatatat tttttcatta gggccatatc tccaaaaaaa gaaagaaaaa     7680

atacaaaaaa caaaaacaaa aaaaaaagag ggtaatgtac aagtttctgt atgtataaag     7740

tcatgctcga tttcaggaga gcagctgatc acaatttgct tcatgaatca aggtgtggaa     7800

atggttatat atggattgat ttagaaaatg gttaccagta cagtcaaaaa agagaaaatg     7860

aaaaaaatac aactaaaagg aagaaacaca acttcaaaga tttttcagtg atgagaatcc     7920

acatttgtat ttcaagataa tgtagtttaa aaaaaaaaaa aagaaaaaaa cttgatgtaa     7980

attcctcctt ttcctctggc ttaatgaata tcatttattc agtataaaat ctttatatgt     8040

tccacatgtt aagaataaat gtacattaaa tcttgttaag cactgtgatg ggtgttcttg     8100

aatactgttc tagtttcctt aaagtggttt cctagtaatc aagttattta caagaaatag     8160

gggaatgcag cagtgtattc acattataaa accctacatt tggaagagac ctttaggggt     8220

tacctacttt agagtgggga gcaacagttt gattttctca aattacttag ctaattagtc     8280

tttctttgaa gcaattaact ctaacgacat tgaggtatga tcattttcag tatttatggg     8340

aggtggctgc tgacccactt gaggtgagat ctcagaagct taactggcct gaaaatgtaa     8400

cattctgcct tttactaact ccatcttagt ttaatcaaag ttcaatctat tccttgtttc     8460

ttctgtgtgc ctcagagtta ttttgcattt agtttactcc accgtgtata atatttatac     8520

tgtgcaatgt taaaaaagaa tctgttatat tgtatgtggt gtacatagtg caaagtgatg     8580

atttctattt cagggcatat tatggttctc atattccttc ctacctggtg cacagtagct     8640

ttttaatact agtcacttct aatttaaact ttctcttcct gggtcattga ctgttactgt     8700

gtaataatcg atttctttga aactgctgca taattatgct gttagtggac ctctacctct     8760

tctcttccct ctcccaatca cagtatactc agaatcccca gcccctcgca tacattgtgt     8820

cggttcacat tactcacagt aatatatgga agagttagac aagaacatgc agttacagtc     8880

attgtgagac gtgactctcc agtgtcacga ggaaaaaaat catcttttct gcaaacagtc     8940

tctcatctgt caactcccac attactgagt caaacagtct tcttacataa caatgcaacc     9000

aaatatatgt tgaattaaag acccatttat aattctgctt taaatacatc tgcttgctaa     9060

gaacagattt cagtgctcca agcttcaaat atggagattt gtaagaggga attcaatatt     9120

attctaattt ctctcttaca gagtacaaat aaaaggtgta tacaaactcc gaacatatcc     9180

agtattccaa ttcctttgtc aatcagaaga gtaaaataat taacaaaaga ctgttgttat     9240

ggtttgcatt gtaaccgata cgcagagtct gaccgttggg caacaagttt ttctatcctg     9300

atgcgcaaca cagtctctag agactaatcc aggaagactt tagcctcctt tccatattct     9360

cacccccgaa tcaagattta cagaagccca cgaagaattt acagcctgct tgagatcatc     9420

ttgcctataa actgagttat tgctttgtcc taaaaattag tcggtttttt tttttctatg     9480

aggcttttca gaaatttaca ggatgcccag actttacatg tgtaccaaaa aaaaaaaaaa     9540

gataaaaaat aaaggtgcaa agaaagttta gtattttgga atggtgctat aaagttgaaa     9600

aaaaaaaaa                                                             9609


<210>  2071
<211>  7629
<212>  DNA
<213>  homo sapiens

<400>  2071
agcggcgcgc gccgaccgcg gcgccaattg gcgagcggct ggagcgcggg gtttcatggg       60

aaggagttgg cccggcttgt ctctctgtca gtggcggctg ctgcctgctc tggaggcagg      120

ctgggcggtg gcggccgaga ctggcggggg tggacgcccg ggccgggctg cgcccgcttc      180

ttgcagctgt gaattccttt ggacaattga tgatatttat cattgtgccc agtttctaca      240

aataaaagat gggtggatta ttttctcgat ggaggacaaa accttcaact gtagaagttc      300

tagaaagtat agataaggaa attcaagcat tggaagaatt tagggaaaaa aatcagagat      360

tacaaaaatt atgggttgga agattaattc tgtattcctc agttctctat ctgtttacat      420

gcttaattgt atatttgtgg tatcttcctg atgaatttac agcaagactt gccatgacac      480

tcccattttt tgcttttcca ttgatcatct ggagcataag aacagtaatt attttcttct      540

tttccaagag aacagaaaga aataatgaag cattggatga tttaaaatcc cagaggaaaa      600

aaatacttga agaagtcatg gaaaaagaaa cttacaagac ggctaaatta attcttgaaa      660

ggtttgatcc ggactcaaag aaagcaaagg agtgtgagcc gccatctgct ggagcagctg      720

taactgcaag acctggacaa gagattcgtc agcgaactgc agctcaaaga aacctttctc      780

caacaccagc aagccctaac cagggccctc ctccacaagt tccagtatct cctggaccac      840

caaaggacag ttctgcccct ggtggacccc cagaaaggac tgttactcca gccctatcat      900

caaatgtgtt accaagacat cttggatccc ctgctacttc agtgcctgga atgggtcttc      960

atcctccagg tccaccttta gcaagaccta ttctcccccg agaacgaggt gctttggata     1020

gaattgttga atatttggtt ggtgatggtc cacaaaacag gtatgcactt atatgtcagc     1080

agtgtttttc tcataatggc atggctttga aggaagaatt tgaatacatt gcttttcgat     1140

gtgcctactg ttttttcttg aaccctgcaa gaaaaaccag acctcaggct ccaagacttc     1200

ctgagtttag ttttgagaag aggcaggtgg tggaaggttc aagttcagtt ggtcccttgc     1260

catcaggaag tgtgctttca tcagacaacc agtttaatga agaatcttta gaacacgatg     1320

ttcttgatga taatacagag cagacagatg acaaaatacc agctacagaa cagacaaacc     1380

aagtgattga aaaagcatct gactcagagg aaccagagga gaaacaagag actgagaatg     1440

aggaagcctc agtgattgaa accaactcca cagttcctgg agctgattct attcctgatc     1500

ctgaactaag tggagaatct ttgacggcag agtagtaaat gcttccacgt gccttcaact     1560

ggatatttat agtcttactg atgtcagtta ttgctttttc ggtggcactt actttttttg     1620

cccctctaag ggtatgcttg tgtatcattt gaattcagat tgcctagcta tttgaacatc     1680

tcaaagttat atatactggg tattaaaatt aaaagcaagt tatatcagtg aagtaagatc     1740

cttttgaatg tacaaagacc cacactattg agacagcttt tagatacttt tttgtccatt     1800

ctaaaagtaa gcaaacatga ttgccttctt gttttctgta tgtataaccc gtaaatatcc     1860

attttgacat aggaagaact ttggttaaga gtaagttctc taattgtgtt tgttttaagg     1920

aatgaaactt ggttaagatt ttgactactt cattattaaa aattgataga attttagctc     1980

ctgagatatt tacaactggg agaaatgtct atttaggtgt ttacattaag cggtatgaaa     2040

gttgttacca cataggcact ggtacgaatt ctcaataaga atgcagtgga acagttaagt     2100

agaactgtaa ctacgttggc actggtacga attctcagtg agaatgcaat gaaacagtca     2160

actgcagtgt ttctttttga tgtcttttat tttacaactg ggccaaaggc acattatgta     2220

tataattagt ttatatttac acactagcat ataggaaata tttctgcact tgaccctatt     2280

tgaattctga gcattattta taagtataaa atgatgatat ataagtgaat tttgtgctct     2340

tgtttgtatt ttattaagga aaatgaaaat aatctggcat cagtttcatt ttgctaaata     2400

tctagtcttc ttcaaacagt atcttggtgg gtgacttggc tacctgaaaa atcttaggag     2460

gaatagctca caatacaata aatctgtaga ttctgcttag agcaaattat ggtactttta     2520

ttcagacttg tttcctttct agttaacaga aatagtgaca tttagaggtt ttaatcagaa     2580

gttaggtttt tctgattcag gaacatcgta ggccagccat ttgtaatttt taactttgag     2640

aaacaaattt tgtgagaata ggtagtgggt tgctggtagt taattggatt taatatttgt     2700

attaaggatt aactggaaaa aatgtgtctc agtgctaatt cttggacctt taatacagtg     2760

tgcttatctg ttacggcctc cttttatctc tcttctccaa tattaaaaaa aatggaaatc     2820

aaattattat gctgaaggga aaaatatacc tgtataagaa tggtgtgttt ggctaatgtt     2880

tctaagttgc acacagttta ttaacaactg aacaaaacat ttttatcatt taaaaatcta     2940

tttttatgat ttaatatctc atatgtgaca gttttttttt tttttttttt ttggaactca     3000

atctgttaac agtctgggac atccggtata gtaaccagag tttttgagcc tgccgtattg     3060

ggcttaaatt tcaggtctgt agtcttgggc aagtcaccta taaactcact gagattattt     3120

tttcatctgt aaaatgggaa gagttatgtt tatttttgaa gggtattagg ataattaaaa     3180

ataatgtaat gtgcctagca cactacctga aaacgatggc atttgttctt attaatgtct     3240

ttaaaatatg caaggaccat aagtttttcc tcttgcagat gaggaaagta aaaaataata     3300

cgaacatgta attcagcttc tcagattcaa gccaatgttt tttgcatcaa cttttctata     3360

ttgtatgtat gtatataaat acatagatta aggaaatagg aaactgaaac tctgtggaat     3420

ataaactttt taaaaataat ttcatcaggt tttttgtatg ttactgaccc atatggattt     3480

tagtaacatc ttgcttagtc atgttgttat aaaacattca aattctgata tacattgctt     3540

gaaaatgagt gagtacctca gagaaatttg atagactcaa acagatagta tgagaaatat     3600

ctttgaaaga aatatggagg aaggttaaaa ggggattagt aaaattaatg cgataggtaa     3660

catgtttgta accatatagt atccttttag atacaaaagc ttattttcat tattattata     3720

ataaacagtt aatggttgaa acttagtaaa atgtcctatt tctgattatt aagactagta     3780

taaatgagaa aatccaagct attaagtacc attagctaca gtgatcttag cttccttgct     3840

tacaattgtt cagtgggtca tctaaattct tctatgtcct gagcatgatc tacaaacatg     3900

gtctagcttc tgtctctccg tcttcccgcc atcattgtgc tgtagccata tggaactcct     3960

ttcagttctc tgaccatgcc ctttcctgcc tcagatttca gcttaaattt tgcctcctca     4020

gagagatgcc ttcccaaact ccccatctga agctggcctc tgccttttac tccctatcat     4080

gtcactctct gctcaccatc cttatcacaa tgtgtatttg atttgtttgc tagtttactg     4140

tcttcacaac ataatgtccg tttgtgcaag ggtcttattt ttcttattca tgtctgtatc     4200

tcaagggtct agcacaatgc ttgatgcata ttgtgtgaat aaatactttg ttgccaaatc     4260

cagtgaaaac tctcagttct tgtttcactg cttggcagta ttgacattga atattctctg     4320

agatactttt tttcttttgg cttttcatat atcacactat tattctctta tttctctggc     4380

ctcttgctct caacgtcctg taagtgttgg tgttccttaa gttctaccta gtgtcatcat     4440

ttcttcattc tgcatattct ttccctaggg tttcttccca acaccaaagg acttaccatc     4500

tgtctctctg aatctcagat ctccagcttt gatctgtttc ctttacttta gagctatata     4560

tttgcctgcc tactggcctg tctctcacaa tccatatatt caagaatgaa cactatactt     4620

tgcttcaaac cttcagaaca ttcaaaccgt ttatgtttct catctaatca aatagagtta     4680

ctctctaagc cagaagctgt aaactcatct cttttccctt tattcaagct gtcaattttt     4740

gtctcctaaa catcttctag ttatattctc atttctctgt tcacattgca ttaataatga     4800

tgataaacat ttgcattctt attctgtgcc aggcaacatg ctaactgctg tatatatatt     4860

attatatttg tactttggca agaatcctgt gaagattttt atctttggac tactagaaga     4920

gaaagctgag ttgtagagag agtatgtatt taagtccgtt tgggctgcta taacagaata     4980

ccacagactg ggtaacgtga tgaacaaaaa tttatttggc tcacagttct ggaacctggg     5040

aaatccaaag gcatgatgct agcatctggt gagggccttt gtgctttgtc atcccatgcc     5100

agaaggcaga agggtaagag agggcaagag tgagcaagag atggaagttg caacctcaag     5160

ctcttttata atgagcatta atccattcat gagggcttca ccctcatgac ctaaacatct     5220

ccattaggct ccaccttcca atgcaacagt tagcataagt tttcaacaca tgctttttgt     5280

agcattcaaa ccatagcagg aagcaacttt gcttaaaatt gtatacctgg taagtggaaa     5340

aagagggatt tgaatatagg caaatgactt cagaggattt actcttaatt tctgttgtac     5400

tgccttctaa tcttggcctc catcatttca gattaccaaa gctgtctctt aactggtttc     5460

tttgtctcca accttgtgca cttgctatct attctgtgtg ctgcagcctg agtttttaaa     5520

aaacagaaaa tgaggggcca ggtgtggtgg tggctcacgc ctgtaatccc agcaagttgg     5580

gaggctgagg cgggcagatc atctggggtc aggagttcga gaccagcctg accaacgtgg     5640

agaaacacta tctctactaa aaatacaaaa ttagccaggc gtggtggtgc atgcctgtaa     5700

tcctagctac tcaggagcct gaggcaggag aattgcttga acacgggagg cagaggttgc     5760

agtgagcaga gattgcgcca ttgtactcca gcctgggcaa caagagtgaa actccatctc     5820

aaaaaaaaaa aagaaagaaa gaaaatgaat ctgccacgcc attgcttaga ccctttaatg     5880

actcttgagt gttcttggga tgaggtccaa atttactaat aaggcctgca aagccctgtg     5940

taattttgct cctagttatg gctggcatct gcaccacaac tacagccact gccacctccc     6000

cctgccacac acacatttta aaagtaacaa tagtagtgtt ttctgtgttt tgcatatgca     6060

gtcttttctc atctcccagc cttcttgagc ttttcctctg cctgagatac gctcccactc     6120

acatagacat tgggggcact aaataaaaat agctgtttaa ttgaattgga atcgttccac     6180

ttggaaccca agtttggaaa ttttgctact tcttgttaag ctaggccttt tattcttgaa     6240

gttgctattt ctcatacaaa ctcattttat gcattagaca cacagtcact attgttatgg     6300

agaacatagt tgtatcagaa gaggtatagc tttgggtgtg gatgtgcgtg tgtcagggga     6360

aagatattct gattatatga tgattttcat aaaatatagt atgctgagtt tccgaaaatc     6420

ctaaatgact tagaaatggt gctatatgtg gtttgtttga cccctgcaaa tctcatgttg     6480

aaatttgatc cccattgctg gaggtgtttt gagcatggag cggatccctc atgaatgtct     6540

tggcgttgtc cttgcagtaa tgagttcttg ctctattttt cctcccctgg aagctgattg     6600

tttaaaagag cctggtatcc tccctccctt tcttctttgc ttcctctctc ttgctgtgtg     6660

atctctgcac acaccagctc ccctttgctt tctgccatga gtggtctgag gctctcacca     6720

gaagccaagc agaggctggc accatgcttc tagtacagcc tgcagaactg taagccaaat     6780

aaacttcttc tttgtttttt ttttttgttt gttttgtttt tttttcagta aattacccag     6840

cctcaggtat tccttaacaa cacaaatggg ctaagacaca gggtcatagg gatagcaggc     6900

acctgagcca agccagaact tagatctcaa ctgttaatgc aggatgattt gtattgaacc     6960

atgaatttta cactgcctct caatgttggt gtcagcattt aaggttattt aaaaaataca     7020

acctgaaggt tacataaagt ttcatttaaa aaataagacc ttataagtct acttttattt     7080

ccagtggaca gcaactactt aatcgtctta aaactttctt cttacaatat tactttacaa     7140

tattacctgt tggatttatt atctgtgtac aaatcagtta gttgaagggc caaagaataa     7200

aggcattttg tgaattatga atagctattt tgaaatggtc atggagacta gctactctag     7260

aaaattggga gaatatactg tattaagtta ctatctggta taacttcaat taattgtgaa     7320

aattgtagca gagatctaga tatagtttat gaacttctaa agagacatta aagggaattc     7380

aagtacttgt gtaaagatga accaaggtag agatgattgt gaattggtga tctgctgtat     7440

gttacagtta tgtaatttga cttgtttcaa aattattaaa gttttaagtg tatgcattct     7500

actggtcaat aagtaaatat attcaggctc tgaatgtaga cagataaata tataaatata     7560

gaaagtacat ttgttagaat acaaacaaga ataaaaattg agtacagaat aaaaaaaaaa     7620

aaaaaaaaa                                                             7629


<210>  2072
<211>  7629
<212>  DNA
<213>  homo sapiens

<400>  2072
agcggcgcgc gccgaccgcg gcgccaattg gcgagcggct ggagcgcggg gtttcatggg       60

aaggagttgg cccggcttgt ctctctgtca gtggcggctg ctgcctgctc tggaggcagg      120

ctgggcggtg gcggccgaga ctggcggggg tggacgcccg ggccgggctg cgcccgcttc      180

ttgcagctgt gaattccttt ggacaattga tgatatttat cattgtgccc agtttctaca      240

aataaaagat gggtggatta ttttctcgat ggaggacaaa accttcaact gtagaagttc      300

tagaaagtat agataaggaa attcaagcat tggaagaatt tagggaaaaa aatcagagat      360

tacaaaaatt atgggttgga agattaattc tgtattcctc agttctctat ctgtttacat      420

gcttaattgt atatttgtgg tatcttcctg atgaatttac agcaagactt gccatgacac      480

tcccattttt tgcttttcca ttgatcatct ggagcataag aacagtaatt attttcttct      540

tttccaagag aacagaaaga aataatgaag cattggatga tttaaaatcc cagaggaaaa      600

aaatacttga agaagtcatg gaaaaagaaa cttacaagac ggctaaatta attcttgaaa      660

ggtttgatcc ggactcaaag aaagcaaagg agtgtgagcc gccatctgct ggagcagctg      720

taactgcaag acctggacaa gagattcgtc agcgaactgc agctcaaaga aacctttctc      780

caacaccagc aagccctaac cagggccctc ctccacaagt tccagtatct cctggaccac      840

caaaggacag ttctgcccct ggtggacccc cagaaaggac tgttactcca gccctatcat      900

caaatgtgtt accaagacat cttggatccc ctgctacttc agtgcctgga atgggtcttc      960

atcctccagg tccaccttta gcaagaccta ttctcccccg agaacgaggt gctttggata     1020

gaattgttga atatttggtt ggtgatggtc cacaaaacag gtatgcactt atatgtcagc     1080

agtgtttttc tcataatggc atggctttga aggaagaatt tgaatacatt gcttttcgat     1140

gtgcctactg ttttttcttg aaccctgcaa gaaaaaccag acctcaggct ccaagacttc     1200

ctgagtttag ttttgagaag aggcaggtgg tggaaggttc aagttcagtt ggtcccttgc     1260

catcaggaag tgtgctttca tcagacaacc agtttaatga agaatcttta gaacacgatg     1320

ttcttgatga taatacagag cagacagatg acaaaatacc agctacagaa cagacaaacc     1380

aagtgattga aaaagcatct gactcagagg aaccagagga gaaacaagag actgagaatg     1440

aggaagcctc agtgattgaa accaactcca cagttcctgg agctgattct attcctgatc     1500

ctgaactaag tggagaatct ttgacggcag agtagtaaat gcttccacgt gccttcaact     1560

ggatatttat agtcttactg atgtcagtta ttgctttttc ggtggcactt actttttttg     1620

cccctctaag ggtatgcttg tgtatcattt gaattcagat tgcctagcta tttgaacatc     1680

tcaaagttat atatactggg tattaaaatt aaaagcaagt tatatcagtg aagtaagatc     1740

cttttgaatg tacaaagacc cacactattg agacagcttt tagatacttt tttgtccatt     1800

ctaaaagtaa gcaaacatga ttgccttctt gttttctgta tgtataaccc gtaaatatcc     1860

attttgacat aggaagaact ttggttaaga gtaagttctc taattgtgtt tgttttaagg     1920

aatgaaactt ggttaagatt ttgactactt cattattaaa aattgataga attttagctc     1980

ctgagatatt tacaactggg agaaatgtct atttaggtgt ttacattaag cggtatgaaa     2040

gttgttacca cataggcact ggtacgaatt ctcaataaga atgcagtgga acagttaagt     2100

agaactgtaa ctacgttggc actggtacga attctcagtg agaatgcaat gaaacagtca     2160

actgcagtgt ttctttttga tgtcttttat tttacaactg ggccaaaggc acattatgta     2220

tataattagt ttatatttac acactagcat ataggaaata tttctgcact tgaccctatt     2280

tgaattctga gcattattta taagtataaa atgatgatat ataagtgaat tttgtgctct     2340

tgtttgtatt ttattaagga aaatgaaaat aatctggcat cagtttcatt ttgctaaata     2400

tctagtcttc ttcaaacagt atcttggtgg gtgacttggc tacctgaaaa atcttaggag     2460

gaatagctca caatacaata aatctgtaga ttctgcttag agcaaattat ggtactttta     2520

ttcagacttg tttcctttct agttaacaga aatagtgaca tttagaggtt ttaatcagaa     2580

gttaggtttt tctgattcag gaacatcgta ggccagccat ttgtaatttt taactttgag     2640

aaacaaattt tgtgagaata ggtagtgggt tgctggtagt taattggatt taatatttgt     2700

attaaggatt aactggaaaa aatgtgtctc agtgctaatt cttggacctt taatacagtg     2760

tgcttatctg ttacggcctc cttttatctc tcttctccaa tattaaaaaa aatggaaatc     2820

aaattattat gctgaaggga aaaatatacc tgtataagaa tggtgtgttt ggctaatgtt     2880

tctaagttgc acacagttta ttaacaactg aacaaaacat ttttatcatt taaaaatcta     2940

tttttatgat ttaatatctc atatgtgaca gttttttttt tttttttttt ttggaactca     3000

atctgttaac agtctgggac atccggtata gtaaccagag tttttgagcc tgccgtattg     3060

ggcttaaatt tcaggtctgt agtcttgggc aagtcaccta taaactcact gagattattt     3120

tttcatctgt aaaatgggaa gagttatgtt tatttttgaa gggtattagg ataattaaaa     3180

ataatgtaat gtgcctagca cactacctga aaacgatggc atttgttctt attaatgtct     3240

ttaaaatatg caaggaccat aagtttttcc tcttgcagat gaggaaagta aaaaataata     3300

cgaacatgta attcagcttc tcagattcaa gccaatgttt tttgcatcaa cttttctata     3360

ttgtatgtat gtatataaat acatagatta aggaaatagg aaactgaaac tctgtggaat     3420

ataaactttt taaaaataat ttcatcaggt tttttgtatg ttactgaccc atatggattt     3480

tagtaacatc ttgcttagtc atgttgttat aaaacattca aattctgata tacattgctt     3540

gaaaatgagt gagtacctca gagaaatttg atagactcaa acagatagta tgagaaatat     3600

ctttgaaaga aatatggagg aaggttaaaa ggggattagt aaaattaatg cgataggtaa     3660

catgtttgta accatatagt atccttttag atacaaaagc ttattttcat tattattata     3720

ataaacagtt aatggttgaa acttagtaaa atgtcctatt tctgattatt aagactagta     3780

taaatgagaa aatccaagct attaagtacc attagctaca gtgatcttag cttccttgct     3840

tacaattgtt cagtgggtca tctaaattct tctatgtcct gagcatgatc tacaaacatg     3900

gtctagcttc tgtctctccg tcttcccgcc atcattgtgc tgtagccata tggaactcct     3960

ttcagttctc tgaccatgcc ctttcctgcc tcagatttca gcttaaattt tgcctcctca     4020

gagagatgcc ttcccaaact ccccatctga agctggcctc tgccttttac tccctatcat     4080

gtcactctct gctcaccatc cttatcacaa tgtgtatttg atttgtttgc tagtttactg     4140

tcttcacaac ataatgtccg tttgtgcaag ggtcttattt ttcttattca tgtctgtatc     4200

tcaagggtct agcacaatgc ttgatgcata ttgtgtgaat aaatactttg ttgccaaatc     4260

cagtgaaaac tctcagttct tgtttcactg cttggcagta ttgacattga atattctctg     4320

agatactttt tttcttttgg cttttcatat atcacactat tattctctta tttctctggc     4380

ctcttgctct caacgtcctg taagtgttgg tgttccttaa gttctaccta gtgtcatcat     4440

ttcttcattc tgcatattct ttccctaggg tttcttccca acaccaaagg acttaccatc     4500

tgtctctctg aatctcagat ctccagcttt gatctgtttc ctttacttta gagctatata     4560

tttgcctgcc tactggcctg tctctcacaa tccatatatt caagaatgaa cactatactt     4620

tgcttcaaac cttcagaaca ttcaaaccgt ttatgtttct catctaatca aatagagtta     4680

ctctctaagc cagaagctgt aaactcatct cttttccctt tattcaagct gtcaattttt     4740

gtctcctaaa catcttctag ttatattctc atttctctgt tcacattgca ttaataatga     4800

tgataaacat ttgcattctt attctgtgcc aggcaacatg ctaactgctg tatatatatt     4860

attatatttg tactttggca agaatcctgt gaagattttt atctttggac tactagaaga     4920

gaaagctgag ttgtagagag agtatgtatt taagtccgtt tgggctgcta taacagaata     4980

ccacagactg ggtaacgtga tgaacaaaaa tttatttggc tcacagttct ggaacctggg     5040

aaatccaaag gcatgatgct agcatctggt gagggccttt gtgctttgtc atcccatgcc     5100

agaaggcaga agggtaagag agggcaagag tgagcaagag atggaagttg caacctcaag     5160

ctcttttata atgagcatta atccattcat gagggcttca ccctcatgac ctaaacatct     5220

ccattaggct ccaccttcca atgcaacagt tagcataagt tttcaacaca tgctttttgt     5280

agcattcaaa ccatagcagg aagcaacttt gcttaaaatt gtatacctgg taagtggaaa     5340

aagagggatt tgaatatagg caaatgactt cagaggattt actcttaatt tctgttgtac     5400

tgccttctaa tcttggcctc catcatttca gattaccaaa gctgtctctt aactggtttc     5460

tttgtctcca accttgtgca cttgctatct attctgtgtg ctgcagcctg agtttttaaa     5520

aaacagaaaa tgaggggcca ggtgtggtgg tggctcacgc ctgtaatccc agcaagttgg     5580

gaggctgagg cgggcagatc atctggggtc aggagttcga gaccagcctg accaacgtgg     5640

agaaacacta tctctactaa aaatacaaaa ttagccaggc gtggtggtgc atgcctgtaa     5700

tcctagctac tcaggagcct gaggcaggag aattgcttga acacgggagg cagaggttgc     5760

agtgagcaga gattgcgcca ttgtactcca gcctgggcaa caagagtgaa actccatctc     5820

aaaaaaaaaa aagaaagaaa gaaaatgaat ctgccacgcc attgcttaga ccctttaatg     5880

actcttgagt gttcttggga tgaggtccaa atttactaat aaggcctgca aagccctgtg     5940

taattttgct cctagttatg gctggcatct gcaccacaac tacagccact gccacctccc     6000

cctgccacac acacatttta aaagtaacaa tagtagtgtt ttctgtgttt tgcatatgca     6060

gtcttttctc atctcccagc cttcttgagc ttttcctctg cctgagatac gctcccactc     6120

acatagacat tgggggcact aaataaaaat agctgtttaa ttgaattgga atcgttccac     6180

ttggaaccca agtttggaaa ttttgctact tcttgttaag ctaggccttt tattcttgaa     6240

gttgctattt ctcatacaaa ctcattttat gcattagaca cacagtcact attgttatgg     6300

agaacatagt tgtatcagaa gaggtatagc tttgggtgtg gatgtgcgtg tgtcagggga     6360

aagatattct gattatatga tgattttcat aaaatatagt atgctgagtt tccgaaaatc     6420

ctaaatgact tagaaatggt gctatatgtg gtttgtttga cccctgcaaa tctcatgttg     6480

aaatttgatc cccattgctg gaggtgtttt gagcatggag cggatccctc atgaatgtct     6540

tggcgttgtc cttgcagtaa tgagttcttg ctctattttt cctcccctgg aagctgattg     6600

tttaaaagag cctggtatcc tccctccctt tcttctttgc ttcctctctc ttgctgtgtg     6660

atctctgcac acaccagctc ccctttgctt tctgccatga gtggtctgag gctctcacca     6720

gaagccaagc agaggctggc accatgcttc tagtacagcc tgcagaactg taagccaaat     6780

aaacttcttc tttgtttttt ttttttgttt gttttgtttt tttttcagta aattacccag     6840

cctcaggtat tccttaacaa cacaaatggg ctaagacaca gggtcatagg gatagcaggc     6900

acctgagcca agccagaact tagatctcaa ctgttaatgc aggatgattt gtattgaacc     6960

atgaatttta cactgcctct caatgttggt gtcagcattt aaggttattt aaaaaataca     7020

acctgaaggt tacataaagt ttcatttaaa aaataagacc ttataagtct acttttattt     7080

ccagtggaca gcaactactt aatcgtctta aaactttctt cttacaatat tactttacaa     7140

tattacctgt tggatttatt atctgtgtac aaatcagtta gttgaagggc caaagaataa     7200

aggcattttg tgaattatga atagctattt tgaaatggtc atggagacta gctactctag     7260

aaaattggga gaatatactg tattaagtta ctatctggta taacttcaat taattgtgaa     7320

aattgtagca gagatctaga tatagtttat gaacttctaa agagacatta aagggaattc     7380

aagtacttgt gtaaagatga accaaggtag agatgattgt gaattggtga tctgctgtat     7440

gttacagtta tgtaatttga cttgtttcaa aattattaaa gttttaagtg tatgcattct     7500

actggtcaat aagtaaatat attcaggctc tgaatgtaga cagataaata tataaatata     7560

gaaagtacat ttgttagaat acaaacaaga ataaaaattg agtacagaat aaaaaaaaaa     7620

aaaaaaaaa                                                             7629


<210>  2073
<211>  8743
<212>  DNA
<213>  homo sapiens

<400>  2073
gtgttccccc cacactgggg ctcccactac tgcgaggagt gacccacgaa ggccacagag       60

atggccgggg cttcggtgaa ggtggcggtg cgggtccgcc ccttcaattc ccgggaaatg      120

agccgtgact ccaagtgcat cattcagatg tctggaagca ccaccaccat tgttaacccc      180

aaacagccca aggagacgcc caaaagcttc agctttgact actcctactg gtcgcacacc      240

tcacctgagg acatcaacta cgcgtcgcag aagcaggtgt accgggacat cggcgaggag      300

atgctgcagc atgcctttga gggatacaac gtgtgcatct tcgcctatgg gcagacgggt      360

gccggcaagt cctacaccat gatgggcaag caggagaagg accagcaggg catcatccca      420

cagctctgcg aggacctctt ctctcggatc aacgacacga ccaacgacaa catgtcctac      480

tccgtggagg tcagctacat ggagatttac tgtgagcgcg tccgtgacct cctgaacccc      540

aagaacaagg gcaaccttcg cgtgagggag cacccactgc tggggcccta cgtggaggac      600

ctctccaagc tggctgtcac ctcctacaat gacatccagg acctcatgga ctcagggaac      660

aaggccagga ccgtggcggc caccaacatg aatgagacca gcagtcgctc ccacgccgtc      720

ttcaacatca tcttcaccca gaagcgccat gacgcagaga ccaatatcac cacggagaag      780

gtgagcaaaa tcagcctggt ggacctggct gggagcgagc gggctgactc cacgggagcc      840

aagggcacgc gcctcaagga gggggccaac atcaacaagt cgctgaccac cctgggcaag      900

gtcatctccg ccctggctga aatggactcc ggacccaaca agaacaagaa aaagaagaag      960

acagatttca ttccgtaccg agattccgtg ttgacctggc tcctccggga aaacctgggc     1020

ggtaactcaa ggacagctat ggtggcagcc ttgagtcctg cagacatcaa ctacgatgag     1080

acccttagca cgctgaggta tgctgaccgg gccaagcaga tccgctgcaa tgctgtcatc     1140

aatgaggacc ccaacaacaa gctgatccgc gagctgaagg atgaggtgac ccggctgcgg     1200

gaccttctgt acgcccaggg tcttggcgac atcactgaca tgaccaatgc cctggtgggt     1260

atgagcccct catcctcgct ctcagccctg tccagccgcg cggcctccgt gtccagcctc     1320

cacgagcgca tcttgtttgc cccgggcagc gaggaggcca ttgaaagact gaaggaaaca     1380

gagaagatca tagctgagct caatgagacc tgggaggaga agctgcggcg gacagaagcc     1440

atccggatgg agagggaagc cctgctggcc gagatgggtg tggccatgag ggaggatggc     1500

ggcaccttgg gcgtattctc tcccaaaaag acaccacacc tcgtcaacct gaacgaggac     1560

ccgctgatgt ctgagtgcct gctctactac atcaaggatg ggatcaccag agtgggcagg     1620

gaggatggcg agaggcggca ggacattgtt ctgagtgggc acttcatcaa ggaggagcac     1680

tgcgtcttcc ggagcgactc caggggaggc agcgaagctg tggtgacctt ggagccctgt     1740

gagggggcag acacctacgt caatggcaag aaagtcacag agcccagcat cctgcgttca     1800

ggaaaccgca tcatcatggg taagagccat gtgttccggt tcaaccaccc cgagcaggcc     1860

cggcaggagc gtgagcgcac gccttgtgcg gagacgccag ctgagcctgt ggactgggcc     1920

ttcgcccagc gtgagctgct ggagaagcag ggcatcgaca tgaagcagga gatggagcag     1980

aggctccagg aactggagga ccagtaccgc cgcgagcggg aggaggccac ctacctgctg     2040

gagcagcagc ggctggacta tgagagcaag ctggaggctc tgcagaagca gatggactcc     2100

aggtactacc cggaggtgaa cgaggaggag gaggagcccg aggatgaagt ccagtggaca     2160

gagcgggagt gtgagctggc gctctgggcc ttccggaagt ggaagtggta ccagttcacg     2220

tctctgcggg acctgctgtg gggcaacgcc atcttcctca aggaggccaa tgccatcagc     2280

gtggagctga aaaagaaggt acaattccag tttgtcctcc tgacggacac actctactcc     2340

cctctgccac ccgacctgct gcccccagag gccgccaaag accgagagac gcggcccttc     2400

ccccgcacca ttgtggccgt ggaggtccag gaccagaaga acggggccac ccactactgg     2460

acgctggaga agctcaggca gcgtctggac ctgatgcggg agatgtacga ccgcgctgca     2520

gaggtgccct ccagtgtcat cgaggactgt gacaacgtgg tgaccggcgg agaccccttc     2580

tatgaccgct tcccctggtt ccggctggtg ggcagggcct tcgtgtacct gagcaacctg     2640

ctgtaccccg ttcccctggt acaccgtgtg gcaatcgtca gcgagaaggg cgaggtgaag     2700

ggcttcctcc gcgtggccgt ccaggccatc tcagccgatg aagaggcccc tgattatggc     2760

tctggcgtcc gccagtcggg aactgctaaa atctcctttg atgaccagca ttttgaaaag     2820

ttccagtccg agtcttgccc cgtggtgggg atgtcccgct cgggaacctc ccaggaagag     2880

cttcgcatcg tggagggcca gggccagggt gcagacgtgg ggccctcagc cgatgaagtc     2940

aacaacaaca cctgttcagc agtgccccca gaaggcctcc tcctagacag ctctgagaaa     3000

gccgccctgg atgggcccct ggatgctgcc ctggaccacc tccgcctggg caacaccttc     3060

accttccgtg tgacagtcct gcaggcgtcc agcatctctg ccgaatatgc cgacatcttc     3120

tgccagttca acttcatcca ccgccacgac gaggccttct ccacagagcc cctgaagaac     3180

acaggcagag gccccccact tggcttctac cacgtccaga acatcgcagt ggaggtgacc     3240

aagtccttca ttgagtacat caagagccag cccattgttt tcgaggtctt tggccactac     3300

cagcagcacc cgttcccgcc cctctgcaag gacgtgctca gccccctgag gccctcgcgc     3360

cgccacttcc ctcgggtcat gccactgtcc aagccagtgc ccgccaccaa gctcagcaca     3420

ctgacgcggc cctgtccggg accctgccac tgcaagtacg acctgctggt ctacttcgag     3480

atctgtgagc tggaggccaa cggcgattac atcccggccg tggtggacca ccgtgggggc     3540

atgccatgca tggggacctt cctcctccac cagggcatcc agcgacggat tacggtgaca     3600

ctactgcatg agacaggcag ccatatccgc tggaaggaag tgcgcgagct ggtcgtgggc     3660

cgcatccgaa acactccaga gaccgacgag tccctgatcg accccaacat cttgtctctc     3720

aacatcctct cttccggata catccaccca gcccaagatg accggacctt ttaccaattt     3780

gaggctgcgt gggacagctc catgcacaac tctctcctgc tgaaccgggt caccccttat     3840

cgagagaaaa tctacatgac actctccgct tatatcgaga tggagaactg cacccagccg     3900

gctgttgtca ccaaggactt ctgcatggtc ttctattccc gtgatgccaa gctgccagcc     3960

tcgcgctcca tccgcaacct ctttggcagt gggagccttc gggcctcaga gagtaaccgt     4020

gtgactggtg tgtacgagct cagcctgtgc cacgtggctg acgcgggcag cccagggatg     4080

cagcgccggc gccgacgagt cctggacaca tctgtggcct atgtccgggg cgaggagaac     4140

ctggcaggct ggaggccccg gagtgacagt ctcattctgg accaccagtg ggagctggag     4200

aagctgagcc tcctgcagga ggtggagaag actaggcact acctgctcct gcgggagaag     4260

ctggagaccg cccagcggcc tgtcccggag gcactgtccc cggccttcag cgaggactct     4320

gagtcccatg gctcctccag cgcctcctcc ccgctctcgg ctgagggccg cccatcaccc     4380

ctggaggctc ccaacgagag gcagcgggag ctggccgtca agtgcttgcg cctgctcacg     4440

cacacattca acagagagta cacacacagc cacgtctgcg tcagtgccag cgagagcaag     4500

ctctccgaga tgtctgtcac cctgctccgg gacccgtcga tgtcccctct aggggtggcc     4560

actctcaccc cctcctccac ttgcccctct ctggttgaag ggcggtacgg tgccactgac     4620

ctgaggaccc cgcagccctg ctcccggcca gccagcccag agcccgagct gctgccagag     4680

gccgactcca agaagctccc ttcccctgcc cgggcaacag agacagacaa ggagccccag     4740

cgcctgctgg tccctgacat ccaggagatc cgagtcagcc cgatcgtttc caagaagggg     4800

tacctgcact tcctggagcc gcacacgtca ggctgggcca ggcgcttcgt ggtggtgcgg     4860

cgcccctatg cctacatgta caacagcgac aaggacaccg tggagcggtt cgtgctcaac     4920

ctggccactg cccaggtgga gtacagtgag gaccagcagg ctatgctcaa gacacccaac     4980

acattcgcgg tgtgcacgga acaccgcggc atcctgctgc aggccgccag cgacaaggac     5040

atgcatgact ggctgtacgc cttcaacccc ctcctggccg ggaccatacg gtccaagctc     5100

tccagaagga ggtctgccca gatgcgggtc tgaacctgag ccctcccgtg acagccggca     5160

ggcccagccc atcccctccc tcatcctcgt ctgtcctgtc acctgccgcc cagcccctct     5220

cctgccagac agcccacgac cgggtcgacc ccccagggga cgcccatgcc aggcccgggg     5280

acctgtgcca cacgaccagc tgtgctccca gcagaggctg tgcgtgtcag ttcttcttgc     5340

agaatgtgct ctggtggaac aagttgggag aggctggggg ggccaagggc acaggttacg     5400

ggggttcttg ctgccgttct aatatttttt taagcataga cagacttata attaatatac     5460

gttagttagt gacattgaaa cagtcaactc ggaaattaac tataagactt gttctattta     5520

taagtattta tttctaatgc ctccacatag ccctgtaata ttcagatgga acccccaacc     5580

acctccaccc tgtttgttcc cacatgtgtc tcccaagcct gctagggaca ggcagggcag     5640

ggacagccac cttggaaggc cgcagtgagg agctgtctgg accagtgggg caccttgggg     5700

ctagcacacg ggtgtatcgc ctgggcccca ggcttctcca tggccacatg ggtcctgggt     5760

gtatgtgtgg gagagtgggg gggtgtcttt ggtgcctgaa gtctgcgcgg catggagggt     5820

ggtgtgagtt cctctggtgg gagggagaac gcacatctct tctgggcggc cacctgagga     5880

gtgactccaa gaagagttcc ggcagctttc cccaggaaag ggtgaggggt gacactcggc     5940

tctggctctg agatgaggca gacggcaccc aggctgtgat ctgtcctggg cggggaccag     6000

gagggagcgg ggtcgggatc acctgccagt gtgcagactc tgggactgcg tgctgtctcc     6060

ggaccatcag ggtagggtgg tgggttgaga ccaggaagtc agggaagatc ggaattcagg     6120

gcgacggtct aggtgtcgag ggctgtggcg cagcctcttc agctgcggcg agaaatggag     6180

tgagtcaagg tagcttctgg gaagaaatgc tgccattagc aggtttcttg caaagacttt     6240

cctctctttg ttcccagggc agagagtttc tgtgagtccc actgagaaaa tcccatgggg     6300

tgggggtatc ctggtcggtc ggcaatggag ggtggctggc ttggtggtta ttgtcttcaa     6360

ggagctcttc gctgctgcat ctgcggtgtc cctttgttct tgtcccattt caccccctct     6420

gcagacacca atgtccgagg gccacccagg acaggacggg ggtcagcccc aagctgagag     6480

tctggtcata ggagtcatgt ccagaggcct agggaggttt tagggccctc cccacccaca     6540

cccacaggtc gatttggtct ctttttagct caaggaaaga cagtagccaa gcaacagagc     6600

ccctctcccg ccgtggcccg tgggagcagt tacatcgggt ctggtgctcc agacctaggg     6660

cccagcactt tcatcagatc ctgcctcctg gagtggggga aacgcagcac cccactggtt     6720

ctgaggcccc taccctccca ggctgtccca cgtgatgctg acatgagcct cagagacccc     6780

aatcccatgc ctgggggaga gacagcggct caggagtggg ggagcacggg ccttctacac     6840

cacatgggaa ggctctggca tgaggttttc ctttgggaag gttgtttggg cccctgaagt     6900

tccatctccg agagtggtgt gcagggcagg ccagggccca tgctggctgc agtctctgtg     6960

gctgcctgcc tgggccagcc tgtttgggag ctgggactgt gggctcgcct tttcgtacct     7020

gggctcaggt gcggtgtggc caccgccacc ctcatcccct gcctgggagg ctctcccagg     7080

ggctgatggg ggggttctgt gagggagaat cagggctcgg gaagccacgc ctgggaaggc     7140

aggacacagg acacagcagc tttctttgga aatctcccag gtgaggattc acatcccaaa     7200

ataaaattca gaagccaggt ggcctgtgct ccccatgggt gacctctgga ggcagtggac     7260

caagatgcag caaggagagg atgcagaaca gcttcttgca gaagcacctg ctccggcatc     7320

cagcgctgcc tggaggcagg aaggagaggc agggcaggac acgctggtct gagatgaggg     7380

ggagccccac gggccccagg caggctagag gaggcacagg ccctgccacg gccaactcag     7440

gtcagccagc ctgaggctgt ggcctccaaa gggtctgggc gcacccccca ggtcgcaggt     7500

gtctgaggcc agccaacctg cagagcactc gcggcgtggg tgggctgagt ggaggtgcct     7560

gggagctgcc taaattcaga agcctccact gccatggaga ctgcctggct gtgtcctctc     7620

agccaggtgc cgtgttggcc ttggctagga cccagagcca cactgcagcc tccgccgact     7680

ccctccttcc gggcctgctc tagtgaggag tgcctaagcc aggacccaga aactcagagt     7740

tgatggtgag aggaggccgc ctgagtcagg acacctggct tcttgaaaag ttcgctctgc     7800

cagaaaccac ctagggacca cgttagctgc cttccttgag ctccccagga gtcggtttcc     7860

acatctgtga ggtggagggc tggtgtggag gtgctcatgg ggtgcggtgc ttgggagaca     7920

gccaggccca gggtggctgc tgcttcctgc taagtggggg aggtgagaca gatctggaaa     7980

gccgtctccc tcagatggtt tcatttaatg ctttatactg ccgagtctgg gggcttgttt     8040

tggtttgggg gcagccatcc tccaccagaa agggggagct ccttccgctg cggctccaga     8100

tagatgggga tgccgggctc caggccgacc agcacttggg atctgatggg acacggccag     8160

tgcctagggg tgccaagtcc aaggcctccc actgggagtc atcgctgaga agatgccaat     8220

gtttcatcca ccggctgcac aggcacaaac tcccccaccc aggacggctg tgatgaggtg     8280

gccctccctg tcaaccctgg tccctggagt ccccagcacc tggggccctg gtggggctga     8340

tgtcacaggt gtttactgtg ctgctgcact ggtcctatgc cagcctcacc catgtgggga     8400

ccacggaagg cacactccct tacccccggt gccgggccgt gcggtccccc agacggacag     8460

cagctgtggc gacctgcgtt tctccctggg cctgtgcttc ctgtagttag tccgtcccct     8520

ggttcccctg tggctcagag gccgcgtccc tggcttgtac atatgtgatt gctgtgggca     8580

caccccagac cccatgtcat agctgccgtc ccgacgtcac gacgcctgtc ccgatgtctt     8640

acacccgagt gttagcccta ggctcctgta ctgtgcgtgc acttgaggct ctgtccaatt     8700

aagaaataaa tgtggctctt actcaacaca gtcaaaaaaa aaa                       8743


<210>  2074
<211>  9916
<212>  DNA
<213>  homo sapiens

<400>  2074
gggaggtggc tgccgggtgg gaggtgtgtg cgcgtgtgcc gcgccgtagg gagcggcggg       60

tcgcgccgcc ggctgtcagc tagctccgcg ccgccgcccg atggcgcgag gaggcgcgcg      120

ggcccagccc cggggggccg gccgcgggtg agcccctcgg cctgccgccc gcgagcatgt      180

cacctccagc cgccgccgcc gcagcctccg ccagccgcgc ccgcgccccc gcctcccgca      240

gccgcagccg ctgcctcggg cattggcccc cagacccccg cctctgatcc acgcccagac      300

cctagctcca gagggccatg gccggccagg gggactgctg cgtcaaggtg gccgtcagga      360

tccggcccca gctgtcgaag gagaagattg agggctgtca catctgtacc tctgttaccc      420

cgggagagcc ccaggtcctg ctggggaagg acaaggcctt cacctatgac tttgtcttcg      480

acctggacac ctggcaagaa cagatctatt ccacctgtgt gagcaagctc atcgagggct      540

gcttcgaggg ctataatgcc acggtgctgg cctatgggca gacgggggcc gggaagacgt      600

acaccatggg cactggcttt gacatggcaa cgtcggagga ggagcagggc atcatcccga      660

gggccatcgc acacctcttt gggggcattg ccgagcgcaa gcgccgggca caggagcagg      720

gcgtggctgg acctgagttc aaagtcagcg cccagtttct ggagctctac aacgaggaga      780

tccttgacct gtttgacagc acccgtgacc ctgacacccg ccaccgcagg tccaacatca      840

agatccacga ggacgcaaac ggtggcatct acaccactgg cgtcacttct cgcctcatcc      900

actcccagga ggagctgatc cagtgcctga agcagggggc cctgtcccgc accacagcca      960

gcacccagat gaacgtgcag agctcacgct cccacgccat cttcaccatc cacctgtgcc     1020

agatgcgcat gtgcacccag cccgacctgg tgaatgaggc ggtgactggg cttcctgatg     1080

gtacacctcc ctcgagtgag tatgagacac tcactgctaa gtttcacttt gtggacctgg     1140

ccggctcaga gcggctgaag cggacagggg ctactggcga gcgggccaag gagggcatct     1200

ccatcaactg tggcctgctg gccttgggca atgtgatcag cgccttaggg gaccagagca     1260

agaaggtggt gcacgttccc tacagggact ccaagctcac tcggctcctc caggattcgc     1320

tggggggcaa cagccagacc atcatgatcg cctgtgtgag cccctcagac cgagatttca     1380

tggagaccct caacacactc aaatatgcca atcgggcccg caacatcaag aacaaggtgg     1440

tagtgaacca ggacaagacc agccagcaaa tcagtgcact gcgggctgag attgctcggc     1500

tgcagatgga gctgatggag tataaggcgg gcaagcgagt gataggagag gatggcgctg     1560

agggctatag tgatctgttc cgagagaatg ccatgctaca gaaggagaat ggggccctgc     1620

ggctgcgggt gaaagccatg caggaggcca tcgatgccat caacaaccgc gtcacccagc     1680

tcatgagcca ggaggccaac ctgctgctag ccaaggccgg cgatggcaat gaggccattg     1740

gtgcgctgat ccagaactac atccgggaga tcgaggagct acggactaag cttctagaga     1800

gtgaagccat gaacgagtcc ctgcgccgca gcctctcacg ggcctcggct aggagcccct     1860

actccctggg tgcttctcca gccgccccgg ccttcggggg cagccctgcc agctccatgg     1920

aggatgcctc ggaggtgatc cgcagggcca agcaggacct ggagcggcta aagaagaagg     1980

aggtcaggca gcggaggaag agccccgaga aggaagcctt caaaaagagg gcaaaactcc     2040

aacaggagaa cagcgaggag acggatgaga acgaggcgga ggaggaggag gaagagcgag     2100

acgagagtgg ctgtgaggag gaggaagggc gcgaggatga agatgaggac tcgggcagtg     2160

aagagagcct ggtggactca gactcagacc ccgaggagaa ggaggtgaac ttccaggcgg     2220

acctggccga cctgacttgt gagatcgaaa tcaagcagaa gctgatcgac gagctggaga     2280

acagccagcg gcggttgcag acgctcaagc accagtatga ggaaaagctg attctgctgc     2340

agaacaagat ccgagacaca cagctggagc gcgaccgtgt gctgcagaac ctcagcacca     2400

tggagtgcta tactgaggag aaggccaaca agatcaaggc agactatgag aagaggctgc     2460

gggagatgaa ccgggacctg cagaagctgc aggccgccca gaaagagcac gcccggctgc     2520

ttaagaacca gtcgcgctac gagagggagc tgaagaagct acaggccgag gtggctgaga     2580

tgaagaaggc caaggtggcc ctgatgaagc agatgcgtga ggagcaacag cggcggcggc     2640

tagtggagac caagaggaac cgggagatcg cacagctcaa gaaggagcag cggcgacagg     2700

agtttcagat ccgagctctg gagtcccaga agcggcagca ggagatggtc ctgaggagga     2760

agacccagga ggtttctgca ctgaggcgcc tggccaagcc catgtctgag cgggtggcag     2820

ggcgtgcagg actaaagcca cccatgctgg actctggggc tgaggtgtcg gccagcacta     2880

cctcatctga ggctgaatca ggggcccgct ctgtctccag catcgtgcgc cagtggaacc     2940

gcaaaatcaa ccacttcttg ggggaccatc ctgcgcccac tgtcaatggc acccgtcctg     3000

cccgaaagaa gttccagaag aagggggcca gccagagctt cagtaaggcg gcaaggctca     3060

agtggcagtc cctggagcga cggatcattg acatcgtcat gcagagaatg accattgtca     3120

acctggaggc tgacatggag cggctcatca agaaaaggga ggagctgttc ctcctgcagg     3180

aggcactgcg gaggaagcgg gagcggctgc aggctgagag ccccgaggaa gagaaggggc     3240

tgcaggagct ggctgaggag atcgaggtgc tggcagccaa cattgactac atcaatgacg     3300

gcatcaccga ctgccaggcc accatcgtgc agctggagga gaccaaggag gagctggact     3360

ccacagacac atccgtggtc atcagctcct gctccctggc tgaagcccgc ctcctgctag     3420

acaacttcct caaggcatcc attgacaagg ggctgcaagt ggcacaaaag gaagcccaga     3480

tccggctgtt ggagggccga ctgaggcaga cggatatggc aggctcctcc cagaaccatc     3540

tgctcctgga cgccctgcgt gagaaggctg aagctcaccc cgagctgcag gccctcatct     3600

acaatgtgca gcaggagaat ggctacgcca gcacagatga ggagatctca gagttctctg     3660

agggcagctt ctcccagtca ttcaccatga aaggctccac cagccatgac gatttcaagt     3720

tcaagagcga gcccaaactg tctgcccaaa tgaaagctgt gtcggctgag tgcctgggcc     3780

ccccactgga tatctccacc aagaacatca ccaagtccct ggcctccctc gttgagatca     3840

aagaggacgg agtgggcttc tctgtccgag acccctatta ccgggacagg gtctcgcgca     3900

ccgtcagtct gcctacccgg ggcagcactt tccctaggca atctcgagcc acagagacgt     3960

ccccgctgac gagaaggaag tcctacgacc gagggcagcc cattaggtcc acagatgtgg     4020

gattcacacc cccatcatcc cctcccactc ggccccgcaa tgaccgcaat gtcttctctc     4080

gtctcaccag taatcagagc caggggtcag cgctggacaa gggcatcatc tccccggttg     4140

gaggagccaa gggtgcacgg acggccccac tgcagtgtgt ctccatggcc gaaggccaca     4200

ccaagcccat cctctgcctg gatgccacag atgagttgct attcacaggg tccaaagacc     4260

gaagctgcaa gatgtggaac ttggttacgg gacaggagat cgcagctcta aagggccacc     4320

ccaacaacgt ggtctccatc aagtactgca gccactcggg gcttgtgttc tccgtgtcca     4380

cctcctacat caaggtgtgg gacatccggg actcagccaa gtgcattcgg actctcacgt     4440

cctcgggcca ggtgatctca ggggatgcct gtgccgccac atccacccgt gccatcacca     4500

gtgctcaggg cgagcatcag atcaaccaga tcgccctcag cccttcgggc accatgctgt     4560

acgccgcctc gggcaatgcc gtccgcatct gggagcttag caggttccag cctgtcggca     4620

agctgactgg ccacatcggc cctgtgatgt gcctgacggt cacccagacg gccagccagc     4680

atgacctcgt ggtgactggc tccaaggacc actacgttaa gatgttcgag ctgggcgagt     4740

gtgtgacggg caccatcggc cccactcaca acttcgagcc cccgcactac gatggcatcg     4800

agtgtctcgc catccaggga gacatcctgt tcagtggctc ccgagataac ggcatcaaga     4860

agtgggacct agaccagcag gagctcatcc agcaaatccc caatgcgcac aaggactggg     4920

tgtgcgccct ggccttcatc ccgggccgcc ccatgctgct cagcgcctgc cgtgcgggtg     4980

tcatcaaggt ctggaacgtg gacaacttca cacccatcgg tgagatcaag ggccacgaca     5040

gtcccatcaa tgccatctgc accaatgcca agcatatctt cacagcctcc agtgactgcc     5100

gggtaaagtt gtggaattac gtccctggac tcaccccctg ccttcctcgc cgagtcctgg     5160

ccataaaggg ccgcgccacc accctgccct gaccctcccc aactctccct gtctcctctt     5220

tcattcttcc cctctttcct tttccctctc tttccccact tcgatctgag ctgcttctta     5280

acggtatgag attattttac tccttcttct tcctttccct tcctgtcctg cctggcctag     5340

agaggtgccc tgcctgtccc tcctgcaccc accgtccttt tccaagcatg aacagtggga     5400

caggccccag gagatgggtg ccagggagca gaagggggag ccttcaggcc tggacaaaac     5460

gaaacacccc cccaaaaaaa gaaaacccat gacaaagctc ccctgggggc ctctgagtgc     5520

acaggcctct ccatctgccc agcaccccac cacctgcagt ccacctcccc gtaagccatg     5580

cttgcctccc agccccaacc acatttgggg agtttgggga atccagttca tcctctactt     5640

ttgggggcag ccagccaagc ccactgcaag agctgaccgg cacccctcca ctttgtcctc     5700

caccccagtg acctgacggt gaagttctgg agtgtccggc ggttacccca cagcggccca     5760

ccctaggagt gaggtcagag ggatgccccc ggaccctcga ccccagcagc ctggacacca     5820

tggaagggaa gctgtgaccc ggccgatggg gccagctgct ctggggacag agggcgtggc     5880

cccctctcct gccctcctcc ctctcccttg gccttcccac aggacactgt tccctcatcc     5940

ctcccctgcc tctcaggagc ctctgggtga gagagaggct ggggaggaaa ttaagctgtg     6000

aagccaaagg gcattatccc ttcttgttcc cctcctggca gtcgtggcca cattgtctcc     6060

tgctgaaccg gctctgcccc tttctcaggc ctttggccca gtggtggagc cctgtgggga     6120

ggtgcagcag cctggcccca tcccaccctt ccgaggagct ggcctccccg cttctcccag     6180

cccagcctct agagccactg cacctgcctc tgagcccaaa aagataagtc ctcaggtagc     6240

taaggaaacc aggtgtgggc ggctgggcct tgcagctaac ccttaaccct ctggcaaccc     6300

gcagatagcc ccaactggcc ccaacagttc cctggggtcc cttttggatg gggccaaggt     6360

ggagctgcta gaaagattcc tttggggaga tggtcagaaa tacttcagtt atttattatt     6420

ttgttatttt tattttttgc tgttgcctcc tggaaacgga cttgaagttt cttcccctat     6480

attctttccc tcagctcttg ggggccagaa atcccaaagg gagtccgctg ccccggccct     6540

ccagggccgc ctcctctgtt tgctttgcag aggagggaac tgctccttcg actctgcagc     6600

tcaggcctgt ccccgacaca gcccccaggg agtcttctag ctacccctgg cctctaggcc     6660

gcctgacgct cagtgccttc ctccgttccg gggcctggca cccgtgccgg gcagccttac     6720

accagccatg cccgcggcac cacatgtgtc ttctcactcg cgaggtcttg tgcccagcgc     6780

ccccgggaag gcgggggcgc tcaccccaca gcccaggccc cggggttctg ccccacagtc     6840

ctgcgtgggc cacgtaggaa gcagcatggg ggctgtgtct gctgggaggt ggcttggatg     6900

gggaggacag cccggcaccc tgacccccgc ccctccccag ccctgcagtc ccccactggg     6960

ccggggagtc tctccagctt ctctctctct ggttattcag gagacacatt ttcggcctta     7020

aaactggcat ggagcgcagg ccctcccttg cagaaaatta tcaaggaaga gggagttggc     7080

agagtttctc tgccccgggg ctggggacgc ggagctccgg ggaaattgtt aaatcagtgt     7140

tctggcgccc cctgttgggg gaactctgga attacaggag tgggccttgg gggggactga     7200

gctccatccc tctcccccgc cccaccccca cccaaagttg cccaccctgt ttttccgttg     7260

catcgctggt cttgtgcttc ccgcttcagt ctgggagcca agagccagcc ccacctccct     7320

tcagaggacg cagtgacttt tggactttcc agaggtggtt ctgtgtttct gcccttggct     7380

cctctccgtc ttgggctggg gcacttggag ccctctccat gtggcgccca gtgttggggg     7440

gaggcaggct ccagtggagg ctgagtgagg cctggtccct tccccgtgcc ctcctcggag     7500

ctgccacaga ggctaagacg gctgtcctgc tggtgctggc cctgctggat gtggtattga     7560

agtctggggc agctgatagc aggaaggaga cccccttgga tgctggtctc ctgggacctg     7620

aacagtctgt cagcaatggc tggaaatcct tcttcctctg gccaccccgg gggtgccggg     7680

caaccccctt agctctaaga tgtggccaca aatctcttcc cactcctccc cgccaacctg     7740

aacagaaagt tttgaccttg caacctgtaa gaaagaatcc gtccgcatga ctgtttacaa     7800

gcgatagaaa cacgtaagac tctgtcccct tgagctccca cccccgggcc ggggatgccc     7860

cacctggggt gactgcactg tagctgcaag gcgtgttctt gcacgaagtg tgatcttatg     7920

gccctgcgag aggtgctcat catcatgccc attttctgct gtttctgatg ggtcagctac     7980

ctcacggcgg ggccagctct gctgtcctgg caagtgtcat tgactctcta aacttgaagt     8040

ccttcaggag ccctgagccc aacatccatg agacaccccg agttgtgctt catgagagtt     8100

ggattctctg cccactcttt cagggatgtc caaggtccat gttagggggc aggcccccag     8160

ctccactcac tgcacaagca ccctaaatgt tggaagcaca aaatggttgt gatttgagca     8220

caatggcagg gtcccgcagg cagacttgac aggcccaggc ccgggaggat ccccccacgt     8280

tggctctgtc caaagtgaga ttgggggtgc ctgtgtctgg gacagggggc tgcccttgct     8340

cagaccaggc cttggctcat ggcttgtcct aattctggga ctcgtcatct tacttcttgc     8400

ccttctgtgc ccatcttaag actggaggct gagccttgtc aggcccagcc acatctttac     8460

gccatgggac caggagtaaa gcgctctcta aaccccgcac cccaaatctc taaacgcctg     8520

agttcaggct gagtcctagc cctagtgagc ctgaagagct tggactgatt cccagtctcc     8580

tgggtcaagc cccactttgt gctttcgaag cttatgagcg ggttccctgg atagaaggag     8640

tcttccatcc ccactgccct tgggcctctt cagcatagtc ctgtgccagg gccctgtcct     8700

cactatcagt cagttcagta tttgctttca cgtgagtggc ggactcttct gaagcagcca     8760

gaactctcaa aggcagcgca tggagttgcc ttgcgagatt tccaaggaag gaggaaagat     8820

taacaggcgg agcctggcac acccaagcct ttgaggtggt cagagtgcca ccttcagccc     8880

cttgggaagg gacagcggtg ggtctgggag tggcctcacc ctggattcag cctaggaatc     8940

tcttcaccct cagctgtcca gccctgctgc ctgtctgggg atgtgtggcc tgggcagagg     9000

gcagtttaaa gcacaaaacc acatggggaa aacacaaggt tgcggggact ttctcatgtg     9060

cctgatgtgg tggagggaga caccagcagg tggctgcagt gacgttaggg aacataacac     9120

ttctttgccc tgctagctct cagctctggg gggcatcccc cgatgtggtc tgggctggga     9180

gcaggcatat cccctggttg ttgcctgtgc ctggtctgtt caccatcgtg tttgtgtggg     9240

cagagcctgc cctgcaggag cagtgacttt cttcccactg tgtgtcccgg acctgtggta     9300

tgtgtccctt tgccatccca aacaggcaac tgcttgctgc tctccttgct tggcatagcc     9360

tcctggtcag tggccaatgc cccacaggcc ttcctgggcc tggccctcct ctcctgactc     9420

ccagatcctt ccctgccctc ttgtgtgcaa ggacagattt tgcagggaaa gttctgtttc     9480

ttctttgata cctttgttct gtcccctgcc ccatccccag cactcatgat cttgaagccc     9540

ctatcacact ctagttcagt cctgtgaacc atgtcctgag ggccttgcag ggaagtagga     9600

aatagaaact cctccacaaa gagccgagga tcagagaaga cccctgagat gaatcagggc     9660

cctgccctgc ccaccaactc ttttctagca atcatgtcct gcccaggctg caggcttcat     9720

taggctcctg ctgtcctcca tgatgtgact agcacaaggt gtatatatgt tttgtacctc     9780

tgccgatggc tgtacatagt gtatgaaagt tatttaagcc ccatgttgta catttctgtt     9840

cctagattgg atgtgtgtgt tctaagaagt tgtcataaat aaaacctgaa tgaccaatgt     9900

caaaaaaaaa aaaaaa                                                     9916


<210>  2075
<211>  4111
<212>  DNA
<213>  homo sapiens

<400>  2075
gatgagcatg tgttgaatcc tcaagagagg agggaggaag caagaaggaa agcttgaagg       60

gaggagggga ggggggcagg tgctgatttc agccctgtag cgtcaggatt gcgtcaattc      120

gggttccagc cacgtctgga gtctcggaga cgagcttctc agaagagcca aaacaggaac      180

cgaggtggca aatcactgtg cgagggcgag tggacctccc tctttgcctc ctccctgttc      240

caggagctgg tgccctgggc tctgcgctgt tgttttcagc gctccgaaag ccggcgcttg      300

agatccaggc aagtgaatcc agccaggcag ttttcccttc agcacctcgg acagaacacg      360

cagtaaaaaa tggctccgat caccaccagc cgggaagaat ttgatgaaat ccccacagtg      420

gtggggatct tcagtgcatt tggcctggtc ttcacagtct ctctctttgc atggatctgc      480

tgtcagagaa aatcatccaa gtctaacaag actcctccat acaagtttgt gcatgtgctt      540

aagggagttg atatttaccc tgaaaaccta aatagcaaaa agaagtttgg agcagatgat      600

aaaaatgaag taaagaataa gccagctgtg ccaaagaatt cattgcatct ggatcttgaa      660

aagagagatc tcaatggcaa ttttcccaaa accaacctca aacctggcag tccttctgat      720

ctggagaatg caaccccgaa gctcttttta gaaggggaaa aagagtcagt ttcccctgag      780

agtttaaagt ccagcacttc ccttacttca gaagagaaac aagagaagct gggaactctc      840

ttcttctcct tagaatacaa cttcgagaga aaagcatttg tggtcaatat caaggaagcc      900

cgtggcttgc cagccatgga tgagcagtcg atgacctctg acccatatat caaaatgacg      960

atcctcccag agaagaagca taaagtgaaa actagagtgc tgagaaaaac cttggatcca     1020

gcttttgatg agacctttac attctatggg ataccctaca cccaaatcca agaattggcc     1080

ttgcacttca caattttgag ttttgacagg ttttcaagag atgatatcat tggggaagtt     1140

ctaattcctc tctcgggaat tgaattatct gaaggaaaaa tgttaatgaa tagagagatc     1200

atcaagagaa atgttaggaa gtcttcagga cggggtgagt tactgatctc tctctgctat     1260

cagtccacca caaacactct aactgtggtt gtcttaaaag ctcgacatct gcctaaatct     1320

gatgtgtccg gactttcaga tccctatgtc aaagtgaacc tgtaccatgc caaaaagaga     1380

atctccaaga agaagactca tgtgaagaaa tgcaccccca atgcagtgtt caatgagctg     1440

tttgtctttg atattccttg tgagggcctt gaagatataa gtgttgaatt tttggttttg     1500

gattctgaaa gggggtcccg aaatgaggta atcgggcagt tagtcttggg tgcagcagca     1560

gaaggaactg gtggagagca ctggaaagag atctgtgact accccaggag acaaattgcc     1620

aagtggcacg tgctctgtga tggttagcat cctagccgtg agttggaact taaaggtttt     1680

tactaggcaa ggagaaattt tctttctttc tatattggat tgcaagcttg ggaaatcaag     1740

ctaccttttt gttgttgttg ttgttgctag aaatggattg aattagtaga ccagaaagta     1800

acttcaaatg tgtattatga taatttccct atttattaga agagttggat aaattttcat     1860

aagatattca atatctcctt cagattacca gtgatataac taggaatagt cagacatttt     1920

atgaatactg tgccagaatc ccaaattata aatgtgacaa tctcattgga acatgtcaca     1980

aaaagttaat gtgattaaga tttaaaaacg aaaagtatgc cttgccttgt gaaaatttat     2040

ccatttatct tcaggttggg gaaatcaatt tttctttaaa tccaaagata ctaaaaaaat     2100

gtcctccagt ttgtatttat taattctgtc atgtgcaaat ggttgtcctg catataaaag     2160

tatctggtca tttcagtttg gtttgtaatt atttgatgca attttatcat aagagtaact     2220

cagattcatt tcaaaaggac agtgaacaag ctgagaaatt attttatcaa agggctgagt     2280

tgagaacact gtggctgaaa tataattttt ctccccccta aggttacatg tgagtcaaaa     2340

ttttgtaaaa tataacctca cataagaacc atggccttgg attattcact gcctgtcaca     2400

agcctcagtg tggcctgaga aatccctatg tacctttgtg aaattgttga attagttagt     2460

gaataaagaa ataaacttca actagaaatc cagttagaag tgcaattttc ttataggaaa     2520

taggtatagt gtgcaagtgt acttttaagg ccatcgtttg tacccagagt cggcatggcc     2580

acctaagtct tcatttaatt tattgtcccc cagaaaagat taagatgcta cttgaaaaga     2640

ctgtgaagat tttttacatt gccagataaa aagtgttact taaccaacaa acaaatgtaa     2700

gactacaaaa tcgttcaaga gcaattctaa tataatttac atatgttcac gcaaaatatg     2760

cttaggctgt caaattagca caacaaagaa tgtgtttcac tatcttttct aggctaattt     2820

gtcttgagct gttgtctata gagcagttta cagacttgtg tcttgtatca ttttccagtg     2880

ccagggttct gaaattcatt cagaacctgt tagattaaag ctgcaccctg tgattatttg     2940

aaaagaatta gcttgagagt aatgtcacta tatttgagtt cttagagaag tatgagtgga     3000

acttgagtac agttgaatta ttaaatatgc aagttagaaa ttaagtctac tgaaaaattt     3060

acattttgag tcaggttttg tgtcagtact ttagcagttt ttgagaatgt gtttgatatc     3120

acagtgtttg taaattctat gaaaaatgca ttttccaaac aacttataca tgctttttat     3180

gactatgcct aatgtaaaga aaatgtatta cattctgtat gtacaaagat taaaaatcaa     3240

cctctttttt gtgctttaaa atgactttgg gattaaaaaa gcatatttcc caatcattgt     3300

cttcattcca ctacaaagtc acctcacagc atcttgctcc actcggcatc tctgtgaaag     3360

caacatgaaa tgaactgtag taggtgtgta gtttggggaa gtcaaatggc cattttatgt     3420

atgtgcattt ggtatcatgg gccgtggaac agaatatatg ttggacctct gaaaagttgt     3480

aaggggccaa ttctaagtat tcttcacggc agccagaagt taatggtggt agcagctgag     3540

gtatggttgt tggacgaggc cgattttttt ttttttaaca tggaacaatg aaaccaacaa     3600

caaacatttt taaaattaaa atggataatt tgtaaatagt ttttagcttt taaaatttaa     3660

agtgtttttg agtgtgaaaa gttgagtaaa actatttgca actggttttc agaaaagaga     3720

aaagaaacaa caaaggaatt gaaacaggca gggagatctt aatacctaat ttcatcattt     3780

ctgaaaatgt actgttttag aatgtattac aatatcaatg tgaatatctt gaatcctgtt     3840

acaaatcctg cactgtatta aacatgtaaa ttaattgttt gtctgattag ccaatctcac     3900

cacccaaatg gggaggtata catgtttgaa gaactgtgta actcagtaat tgatttgttc     3960

tgatgttgta actcaataga agtgttttgg aaggaagcat ggtgtgtgag acagtgtctg     4020

ttcttttgtg ccagctctgt atgatgtttg taagaccatg tttgtaagac atgaataaat     4080

tgctgctttt gcccaaaaaa aaaaaaaaaa a                                    4111


<210>  2076
<211>  9717
<212>  DNA
<213>  homo sapiens

<400>  2076
gcctgctcca agggaaggat caggagagaa gaaacgcaaa tcccagaacc gtgccaacat       60

ataaaacccc acattaaggg ttgtacagtg cactgggatt tctcaagtca cccgcttggt      120

cctcttccaa gtatacttta cttcctttca ttcctctcta aaactttttt aaaaactttc      180

actcctgctc taaaagttat cttggtttct tactctacct tatgcccctt gggcgaattt      240

tttcctctga ggagggaaga atagagttgc tgctgcagac acatcagatt ccctactggt      300

aacagctgga gtgcgtcacc tctgacaaaa ttctggggac gctgggaaca ctgaatcaac      360

atgggcaatg agaacagcac ctcggacaac cagaggactt tatcagctca gactccaagg      420

tccgcgcagc cacccgggaa cagtcagaat ataaaaagga agcagcagga cacgcccgga      480

agccctgacc acagagacgc gtccagcatt ggcagcgttg ggcttggagg cttctgcacc      540

gcttctgaga gttctgccag cctggatcca tgccttgtgt ccccagaggt gactgagcca      600

aggaaggacc cacagggagc cagggggcca gaaggttctt tgctgcccag cccaccaccg      660

tcccaggagc gagagcaccc ctcgtcctcc atgccctttg ccgagtgtcc cccggaaggt      720

tgcttggcaa gtccagcagc ggcacctgaa gatggtcctc agactcagtc tcccaggagg      780

gaacctgccc caaatgcccc aggagacatc gcggcggcat ttcccgctga gagggacagc      840

tctactccat accaagagat tgctgccgtc cccagtgctg gaagagagag acagccgaag      900

gaagaaggac agaagtcctc cttctccttc tccagtggca tcgaccagtc acctggaatg      960

tcgccagtac ccctcagaga gccaatgaag gcaccgctgt gtggagaggg ggaccagcct     1020

ggtggttttg agtcccaaga gaaagaggct gcaggtggct ttccccctgc agagtccagg     1080

cagggggtgg cttctgtgca agtgacccct gaggcccctg ctgcagccca gcagggcaca     1140

gaaagctcag cggtcttgga gaagtccccc ctaaaaccca tggccccgat cccacaagat     1200

ccagccccaa gagcctcaga cagagaaaga ggccaagggg aggcgccgcc tcagtattta     1260

acagatgact tggaattcct cagggcctgc catctcccta ggagcaattc aggggctgcc     1320

ccagaagcag aagtgaatgc cgcttcccag gagagctgcc agcagccagt gggagcatat     1380

ctgccgcacg cagagctgcc ctggggcttg ccaagtcctg ccctggtgcc agaggctggg     1440

ggctctggga aggaggctct ggacaccatt gatgttcagg gtcacccaca gacagggatg     1500

cgaggaacca agcccaatca agttgtctgt gtggcagcag gcggccagcc cgaagggggt     1560

ttgcctgtga gccctgaacc ttccctgctc actccgactg aggaagcaca tccagcttca     1620

agcctcgctt cattcccagc tgctcagatt cctattgctg tagaagaacc tggatcatca     1680

tccagggaat cagtttccaa ggctgggatg ccagtttctg cagatgcagc caaagaggtg     1740

gtggatgcag ggttggtggg actggagagg caggtgtcag atcttggaag caagggagag     1800

catccagaag gggaccctgg agaggttcct gccccatcac cccaggagag gggagagcac     1860

ttgaacacgg agcaaagcca tgaggtccaa ccaggagtac caccccctcc tcttcccaag     1920

gagcaaagcc atgaggtcca accaggagca ccaccccctc ctcttcccaa ggcaccaagt     1980

gaaagtgcca gagggccacc ggggccaacg gatggagcca aggtccatga agattccaca     2040

agcccagccg tggctaaaga aggaagcaga tcacctggtg acagccctgg aggaaaggag     2100

gaagccccag agccacctga tggtggagac ccagggaacc tgcaaggaga ggactctcag     2160

gctttcagca gcaagcgtga tccagaagta ggcaaagatg agctttcaaa gccaagcagt     2220

gatgcagaga gcagagacca tcccagctca cactcagcac agccacccag aaaggggggt     2280

gctgggcaca cggacgggcc ccactctcag acagcagagg ctgatgcatc tggcctacca     2340

cacaagctgg gtgaggagga ccccgtcctg ccccctgtgc cagatggagc tggtgagccc     2400

actgttcccg aaggagccat ctgggagggg tcaggattgc agcccaaatg tcctgacacc     2460

cttcagagca gggaaggatt gggaagaatg gagtctttcc tgactttaga atcagagaaa     2520

tcagattttc caccaactcc tgttgcagag gttgcaccca aagcccagga aggtgagagc     2580

acattggaaa taaggaagat gggcagctgt gatggggagg gcttgctgac gtccccagat     2640

caaccccgcg ggccggcgtg tgatgcgtcg agacaggaat ttcatgctgg ggtgccacat     2700

cccccccagg gggagaactt ggcagcagac ctggggctca cggcactcat cctggaccaa     2760

gatcagcagg gaatcccatc ctgcccaggg gaaggctgga taagaggagc tgcatccgag     2820

tggcccctac tatcttctga gaagcatctc cagccatccc aggcacaacc agagacatcc     2880

atctttgacg tgctcaagga gcaggcccag ccacctgaaa atgggaaaga gacttctcca     2940

agccatccag gttttaagga ccagggagca gattcttccc aaatccatgt acctgtggaa     3000

cctcaggaag ataacaactt gcccactcat ggaggacagg agcaggcttt gggatcagaa     3060

cttcaaagtc agctccccaa aggcaccctg tctgatactc caacttcatc tcccactgac     3120

atggtttggg agagttctct gacagaagag tcagaattgt cagcaccaac gagacagaag     3180

ttgcctgcac taggggagaa gcggccagag ggagcatgcg gtgatggtca gtcctcgagg     3240

gtctcgcctc cagcagcaga tgtcttaaaa gacttttctc ttgcagggaa cttcagcaga     3300

aaggaaactt gctgcactgg gcaggggcca aacaagtctc aacaggcatt ggctgatgcc     3360

ttggaagaag gcagccagca tgaagaagca tgtcaaaggc atccaggagc ttctgaagca     3420

gctgatggtt gttccccact ctggggcttg agtaagaggg agatggcaag tggaaacaca     3480

ggggaggccc caccttgtca gcctgactca gtagctctcc tggatgcagt tccctgcctg     3540

ccagccctgg cgcccgccag ccccggagtc acacccaccc aggatgcccc agagacagag     3600

gcatgtgatg aaacccagga aggcaggcag caaccagtgc cggccccgca gcagaaaatg     3660

gagtgccggg ccacttcgga tgcagagtcc ccaaagcttc ttgcaagttt cccatcagct     3720

ggggagcaag gtggtgaagc cggggctgct gagactggtg gcagcgctgg tgcaggagac     3780

ccaggaaagc agcaggctcc ggagaaacct ggagaagcta ctttgagttg tggcctcctt     3840

cagactgagc actgccttac ctccggggag gaagcttcta cctctgccct acgtgagtcc     3900

tgccaagctg agcaccccat ggccagctgc caggatgcct tgctgccagc cagagagctg     3960

ggtgggattc ccaggagcac catggatttt tctacacacc aggctgtccc agacccaaag     4020

gagctcctgc tgtctgggcc accagaagtg gctgctcctg acacccctta cctgcatgtc     4080

gacagtgctg cccagagagg agcagaagac agtggagtga aagctgtttc ctctgcagac     4140

cccagagctc ctggcgaaag cccctgtcct gtaggggagc ccccacttgc cttggaaaat     4200

gctgcctcct tgaagctgtt tgctggctcc ctcgcccccc tgttgcaacc aggagctgca     4260

ggtggggaaa tccctgcagt gcaagccagc agtggtagtc ccaaagccag aaccactgag     4320

ggaccagtgg actccatgcc atgcctggac cggatgccac ttctggccaa gggcaagcag     4380

gcaacagggg aagagaaagc agcaacagct ccaggtgcag gtgccaaggc cagtggggag     4440

ggcatggcag gtgatgcagc aggagagaca gagggcagca tggagaggat gggagagcct     4500

tcccaggacc caaagcaggg cacatcaggt ggtgtggaca caagctctga gcaaatcgcc     4560

accctcactg gcttcccaga cttcagggag cacatcgcca agatcttcga gaagcctgtg     4620

ctcggagccc tggccacacc tggagaaaag gcaggagctg ggaggagtgc agtgggtaaa     4680

gacctcacca ggccattggg cccagagaag cttctagatg ggcctccagg agtggatgtc     4740

acccttctcc ctgcacctcc tgctcgactc caggtggaga agaagcaaca gttggctgga     4800

gaggctgaga tttcccatct ggctctgcaa gatccagctt cagacaagct tctgggtcca     4860

gcagggctga cctgggagcg gaacttgcca ggtgccggtg tggggaagga gatggcaggt     4920

gtcccaccca cactgaggga agacgagagg ccagaggggc ctggggcagc ctggccaggc     4980

ctggaaggcc aggcttactc acagctggag aggagcaggc aggaattagc ttcaggtctt     5040

ccttcaccag cagctactca ggagctccct gtggagagag ctgctgcctt ccaggtggct     5100

ccccatagcc atggagaaga ggccgtggcc caagacagaa ttccttctgg aaagcagcac     5160

caggaaacat ctgcctgcga cagtccacat ggagaagatg gtcccgggga ctttgctcac     5220

acaggggttc caggacatgt gccaaggtcc acgtgtgccc cttctcctca gagggaggtt     5280

ttgactgtgc ctgaggccaa cagtgagccc tggacccttg acacgcttgg gggtgaaagg     5340

agacccggag tcactgctgg catcttggaa atgcgaaatg ccctgggcaa ccagagcacc     5400

cctgcaccac caactggaga agtggcagac actcccctgg agcctggcaa ggtggcaggc     5460

gctgctgggg aagcagaggg tgacatcacc ctgagcacag ctgagacaca ggcatgtgcg     5520

tccggtgatc tgcctgaagc aggtactacg aggacattct ccgttgtggc aggtgacttg     5580

gtgctgccag gaagctgtca ggacccagcc tgctctgaca aggctccggg gatggagggt     5640

acagctgccc ttcatgggga cagcccagcc aggccccagc aggctaagga gcagccaggg     5700

cctgagcgcc ccattccagc tggggatggg aaggtgtgcg tctcctcacc tccagagcct     5760

gacgaaactc acgacccgaa gctgcaacat ttggctccag aagagctcca cactgacaga     5820

gagagcccca ggcctggccc atccatgtta ccttcggttc ctaagaagga tgctccaaga     5880

gtcatggata aagtcacttc agatgagacc agaggtgcgg aaggaacaga aagttcacct     5940

gtggcagatg atatcatcca gcccgctgcc cccgcagacc tggaaagccc aaccttagct     6000

gcctcttcct accacggtga tgttgttggc caggtctcta cggatctgat agcccagagc     6060

atctccccag ctgctgccca tgcgggtctt cctccctcgg ctgcagaaca catagtttcg     6120

ccatctgccc cagctggtga cagagtagaa gcttccactc cctcctgccc agatccggcc     6180

aaggacctca gcaggagttc cgattctgaa gaggcatttg agaccccgga gtcaacgacc     6240

cctgtcaaag ctccgccagc tccaccccca ccaccccccg aagtcatccc agaacccgag     6300

gtcagcacac agccaccccc ggaagaacca ggatgtggtt ctgagacagt ccctgtccct     6360

gatggcccac ggagcgactc ggtggaagga agtcccttcc gtcccccgtc acactccttc     6420

tctgccgtct tcgatgaaga caagccgata gccagcagtg ggacttacaa cttggacttt     6480

gacaacattg agcttgtgga tacctttcag accttggagc ctcgtgcctc agacgctaag     6540

aatcaggagg gcaaagtgaa cacacggagg aagtccacgg attccgtccc catctctaag     6600

tctacactgt cccggtcgct cagcctgcaa gccagtgact ttgatggtgc ttcttcctca     6660

ggcaatcccg aggccgtggc ccttgcccca gatgcatata gcacgggttc cagcagtgct     6720

tctagtaccc ttaagcgaac taaaaaaccg aggccgcctt ccttaaaaaa gaaacagacc     6780

accaagaaac ccacagagac ccccccagtg aaggagacgc aacaggagcc agatgaagag     6840

agccttgtcc ccagtgggga gaatctagca tctgagacga aaacggaatc tgccaagacg     6900

gaaggtccta gcccagcctt attggaggag acgccccttg agcccgctgt ggggcccaaa     6960

gctgcctgcc ctctggactc agagagtgca gaaggggttg tccccccggc ttctggaggt     7020

ggcagagtgc agaactcacc ccctgtcggg aggaaaacgc tgcctcttac cacggccccg     7080

gaggcagggg aggtaacccc atcggatagc ggggggcaag aggactctcc agccaaaggg     7140

ctctccgtaa ggctggagtt tgactattct gaggacaaga gtagttggga caaccagcag     7200

gaaaaccccc ctcctaccaa aaagataggc aaaaagccag ttgccaaaat gcccctgagg     7260

aggccaaaga tgaaaaagac acccgagaaa cttgacaaca ctcctgcctc acctcccaga     7320

tcccctgctg aacccaatga catccccatt gctaaaggta cttacacctt tgatattgac     7380

aagtgggatg accccaattt taaccctttt tcttccacct caaaaatgca ggagtctccc     7440

aaactgcccc aacaatcata caactttgac ccagacacct gtgatgagtc cgttgacccc     7500

tttaagacat cctctaagac ccccagctca ccttctaaat ccccagcctc ctttgagatc     7560

ccagccagtg ctatggaagc caatggagtg gacggggatg ggctaaacaa gcccgccaag     7620

aagaagaaga cgcccctaaa gactgacaca tttagggtga aaaagtcgcc aaaacggtct     7680

cctctctctg atccaccttc ccaggacccc accccagctg ctacaccaga aacaccacca     7740

gtgatctctg cggtggtcca cgccacagat gaggaaaagc tggcggtcac caaccagaag     7800

tggacgtgca tgacagtgga cctagaggct gacaaacagg actacccgca gccctcggac     7860

ctgtccacct ttgtaaacga gaccaaattc agttcaccca ctgaggagtt ggattacaga     7920

aactcctatg aaattgaata tatggagaaa attggctcct ccttacctca ggacgacgat     7980

gccccgaaga agcaggcctt gtaccttatg tttgacactt ctcaggagag ccctgtcaag     8040

tcatctcccg tccgcatgtc agagtccccg acgccgtgtt cagggtcaag ttttgaagag     8100

actgaagccc ttgtgaacac tgctgcgaaa aaccagcatc ctgtcccacg aggactggcc     8160

cctaaccaag agtcacactt gcaggtgcca gagaaatcct cccagaagga gctggaggcc     8220

atgggcttgg gcaccccttc agaagcgatt gaaattacag ctcccgaggg ctcctttgcc     8280

tctgctgacg ccctcctcag caggctagct caccccgtct ctctctgtgg tgcacttgac     8340

tatctggagc ccgacttagc agaaaagaac cccccactat tcgctcagaa actccaggag     8400

gagttagagt ttgccatcat gcggatagaa gccctgaagc tggccaggca gattgctttg     8460

gcttcccgca gccaccagga tgccaagaga gaggctgctc acccaacaga cgtctccatc     8520

tccaaaacag ccttgtactc ccgcatcggg accgctgagg tggagaaacc tgcaggcctt     8580

ctgttccagc agcccgacct ggactctgcc ctccagatcg ccagagcaga gatcataacc     8640

aaggagagag aggtctcaga atggaaagat aaatatgaag aaagcaggcg ggaagtgatg     8700

gaaatgagga aaatagtggc cgagtatgag aagaccatcg ctcagatgat agaggacgaa     8760

cagagagaga agtcagtctc ccaccagacg gtgcagcagc tggttctgga gaaggagcaa     8820

gccctggccg acctgaactc cgtggagaag tctctggccg acctcttcag aagatatgag     8880

aagatgaagg aggtcctaga aggcttccgc aagaatgaag aggtgttgaa gagatgtgcg     8940

caggagtacc tgtcccgggt gaagaaggag gagcagaggt accaggccct gaaggtgcac     9000

gcggaggaga aactggacag ggccaatgct gagattgctc aggttcgagg caaggcccag     9060

caggagcaag ccgcccacca ggccagcctg cggaaggagc agctgcgagt ggacgccctg     9120

gaaaggacgc tggagcagaa gaataaagaa atagaagaac tcaccaagat ttgtgacgaa     9180

ctgattgcca aaatggggaa aagctaactc tgaaccgaat gttttggact taactgttgc     9240

gtgcaatatg accgtcggca cactgctgtt cctccagttc catggacagg ttctgttttc     9300

actttttcgt atgcactact gtatttcctt tctaaataaa attgatttga ttgtatgcag     9360

tactaaggag actatcagaa tttcttgcta ttggtttgca ttttcctagt ataattcata     9420

gcaagttgac ctcagagttc ctgtatcagg gagattgtct gattctctaa taaaagacac     9480

attgctgacc ttggccttgc cctttgtaca caagttccca gggtgagcag cttttggatt     9540

taatatgaac atgtacagcg tgcataggga ctcttgcctt aaggagtgta aacttgatct     9600

gcatttgctg atttgttttt aaaaaaacaa gaaatgcatg tttcaaataa aattctctat     9660

tgtaaataaa attttttctt tggatcttgg caataaaaaa aaaaaaaaaa aaaaaaa        9717


<210>  2077
<211>  4090
<212>  DNA
<213>  homo sapiens

<400>  2077
gcgggcggtc ccggcgaggc gggaggggcc ggggcagagg gagggtcttc gcctccccac       60

ccccagcccc gtttccggag cccgcgatgg agctttgtga agatgcaggc gttggggctg      120

ctcggcgatg atgacatcat cgtgtcacac acaggagccg gctgccgggg ggtttaagag      180

aagagccttt cggaccacac cggcgctcac gctcataccc gcacgccccg ggcagagccg      240

cgcacgccgg ccacactcgg gcgcgcgccg gccacactcg cgcgcacaca tacgcggcgc      300

tcgccccccg gcccccggct cgggccgcga gtcgcagctc cctgccgccg ctcccgccgc      360

cacggatgcc cgcagctgct cccctctgca gtgcagcaac cccggccgcc ggccggctcg      420

ccccggctcc cggctgcagg aatcgcgcca ggacgctggc cccgctcgcg gctagcttgc      480

acgccagggc acagcgagga tgggagggtc gcagtccctg cagccagccc cagccagcga      540

cctgaacctg gaggcttccg aggcaatgag ttccgattct gaagaggcat ttgagacccc      600

ggagtcaacg acccctgtca aagctccgcc agctccaccc ccaccacccc ccgaagtcat      660

cccagaaccc gaggtcagca cacagccacc cccggaagaa ccaggatgtg gttctgagac      720

agtccctgtc cctgatggcc cacggagcga ctcggtggaa ggaagtccct tccgtccccc      780

gtcacactcc ttctctgccg tcttcgatga agacaagccg atagccagca gtgggactta      840

caacttggac tttgacaaca ttgagcttgt ggataccttt cagaccttgg agcctcgtgc      900

ctcagacgct aagaatcagg agggcaaagt gaacacacgg aggaagtcca cggattccgt      960

ccccatctct aagtctacac tgtcccggtc gctcagcctg caagccagtg actttgatgg     1020

tgcttcttcc tcaggcaatc ccgaggccgt ggcccttgcc ccagatgcat atagcacggg     1080

ttccagcagt gcttctagta cccttaagcg aactaaaaaa ccgaggccgc cttccttaaa     1140

aaagaaacag accaccaaga aacccacaga gaccccccca gtgaaggaga cgcaacagga     1200

gccagatgaa gagagccttg tccccagtgg ggagaatcta gcatctgaga cgaaaacgga     1260

atctgccaag acggaaggtc ctagcccagc cttattggag gagacgcccc ttgagcccgc     1320

tgtggggccc aaagctgcct gccctctgga ctcagagagt gcagaagggg ttgtcccccc     1380

ggcttctgga ggtggcagag tgcagaactc accccctgtc gggaggaaaa cgctgcctct     1440

taccacggcc ccggaggcag gggaggtaac cccatcggat agcggggggc aagaggactc     1500

tccagccaaa gggctctccg taaggctgga gtttgactat tctgaggaca agagtagttg     1560

ggacaaccag caggaaaacc cccctcctac caaaaagata ggcaaaaagc cagttgccaa     1620

aatgcccctg aggaggccaa agatgaaaaa gacacccgag aaacttgaca acactcctgc     1680

ctcacctccc agatcccctg ctgaacccaa tgacatcccc attgctaaag gtacttacac     1740

ctttgatatt gacaagtggg atgaccccaa ttttaaccct ttttcttcca cctcaaaaat     1800

gcaggagtct cccaaactgc cccaacaatc atacaacttt gacccagaca cctgtgatga     1860

gtccgttgac ccctttaaga catcctctaa gacccccagc tcaccttcta aatccccagc     1920

ctcctttgag atcccagcca gtgctatgga agccaatgga gtggacgggg atgggctaaa     1980

caagcccgcc aagaagaaga agacgcccct aaagactgac acatttaggg tgaaaaagtc     2040

gccaaaacgg tctcctctct ctgatccacc ttcccaggac cccaccccag ctgctacacc     2100

agaaacacca ccagtgatct ctgcggtggt ccacgccaca gatgaggaaa agctggcggt     2160

caccaaccag aagtggacgt gcatgacagt ggacctagag gctgacaaac aggactaccc     2220

gcagccctcg gacctgtcca cctttgtaaa cgagaccaaa ttcagttcac ccactgagga     2280

gttggattac agaaactcct atgaaattga atatatggag aaaattggct cctccttacc     2340

tcaggacgac gatgccccga agaagcaggc cttgtacctt atgtttgaca cttctcagga     2400

gagccctgtc aagtcatctc ccgtccgcat gtcagagtcc ccgacgccgt gttcagggtc     2460

aagttttgaa gagactgaag cccttgtgaa cactgctgcg aaaaaccagc atcctgtccc     2520

acgaggactg gcccctaacc aagagtcaca cttgcaggtg ccagagaaat cctcccagaa     2580

ggagctggag gccatgggct tgggcacccc ttcagaagcg attgaaatta cagctcccga     2640

gggctccttt gcctctgctg acgccctcct cagcaggcta gctcaccccg tctctctctg     2700

tggtgcactt gactatctgg agcccgactt agcagaaaag aaccccccac tattcgctca     2760

gaaactccag gaggagttag agtttgccat catgcggata gaagccctga agctggccag     2820

gcagattgct ttggcttccc gcagccacca ggatgccaag agagaggctg ctcacccaac     2880

agacgtctcc atctccaaaa cagccttgta ctcccgcatc gggaccgctg aggtggagaa     2940

acctgcaggc cttctgttcc agcagcccga cctggactct gccctccaga tcgccagagc     3000

agagatcata accaaggaga gagaggtctc agaatggaaa gataaatatg aagaaagcag     3060

gcgggaagtg atggaaatga ggaaaatagt ggccgagtat gagaagacca tcgctcagat     3120

gatagaggac gaacagagag agaagtcagt ctcccaccag acggtgcagc agctggttct     3180

ggagaaggag caagccctgg ccgacctgaa ctccgtggag aagtctctgg ccgacctctt     3240

cagaagatat gagaagatga aggaggtcct agaaggcttc cgcaagaatg aagaggtgtt     3300

gaagagatgt gcgcaggagt acctgtcccg ggtgaagaag gaggagcaga ggtaccaggc     3360

cctgaaggtg cacgcggagg agaaactgga cagggccaat gctgagattg ctcaggttcg     3420

aggcaaggcc cagcaggagc aagccgccca ccaggccagc ctgcggaagg agcagctgcg     3480

agtggacgcc ctggaaagga cgctggagca gaagaataaa gaaatagaag aactcaccaa     3540

gatttgtgac gaactgattg ccaaaatggg gaaaagctaa ctctgaaccg aatgttttgg     3600

acttaactgt tgcgtgcaat atgaccgtcg gcacactgct gttcctccag ttccatggac     3660

aggttctgtt ttcacttttt cgtatgcact actgtatttc ctttctaaat aaaattgatt     3720

tgattgtatg cagtactaag gagactatca gaatttcttg ctattggttt gcattttcct     3780

agtataattc atagcaagtt gacctcagag ttcctgtatc agggagattg tctgattctc     3840

taataaaaga cacattgctg accttggcct tgccctttgt acacaagttc ccagggtgag     3900

cagcttttgg atttaatatg aacatgtaca gcgtgcatag ggactcttgc cttaaggagt     3960

gtaaacttga tctgcatttg ctgatttgtt tttaaaaaaa caagaaatgc atgtttcaaa     4020

taaaattctc tattgtaaat aaaatttttt ctttggatct tggcaataaa aaaaaaaaaa     4080

aaaaaaaaaa                                                            4090


<210>  2078
<211>  356
<212>  DNA
<213>  homo sapiens

<400>  2078
atgtctggcc gcggcaaagg cgggaagggt cttggcaaag gcggcgctaa gcgccaccgt       60

aaagtactgc gcgacaatat ccagggcatc accaagccgg ccatccggcg ccttgctcgc      120

cgcggcggcg tgaagcgcat ctccggcctc atctacgagg agactcgcgg ggtgctgaag      180

gtgttcctgg agaacgtgat ccgggacgcc gtgacctata cagagcacgc caagcgcaag      240

acggtcaccg ccatggatgt ggtctacgcg ctcaagcgcc agggccgcac cctctacggt      300

ttcggtggtt gagcgtccct ttctatcaat aaaaggccct tttcagggcc acccta          356


<210>  2079
<211>  1439
<212>  DNA
<213>  homo sapiens

<400>  2079
tttctacttt gcccgcccac agatgtagtt ttctctgcgc gtgtgcgttt tccctcctcc       60

ccgccctcag ggtccacggc caccatggcg tattaggggc agcagtgcct gcggcagcat      120

tggcctttgc agcggcggca gcagcaccag gctctgcagc ggcaaccccc agcggcttaa      180

gccatggcgc ttctcacggc attcagcagc agcgttgctg taaccgacaa agacaccttc      240

gaattaagca cattcctcga ttccagcaaa gcaccgcaac atgaccgaaa tgagcttcct      300

gagcagcgag gtgttggtgg gggacttgat gtcccccttc gaccagtcgg gtttgggggc      360

tgaagaaagc ctaggtctct tagatgatta cctggaggtg gccaagcact tcaaacctca      420

tgggttctcc agcgacaagg ctaaggcggg ctcctccgaa tggctggctg tggatgggtt      480

ggtcagtccc tccaacaaca gcaaggagga tgccttctcc gggacagatt ggatgttgga      540

gaaaatggat ttgaaggagt tcgacttgga tgccctgttg ggtatagatg acctggaaac      600

catgccagat gaccttctga ccacgttgga tgacacttgt gatctctttg cccccctagt      660

ccaggagact aataagcagc ccccccagac ggtgaaccca attggccatc tcccagaaag      720

tttaacaaaa cccgaccagg ttgccccctt caccttctta caacctcttc ccctttcccc      780

aggggtcctg tcctccactc cagatcattc ctttagttta gagctgggca gtgaagtgga      840

tatcactgaa ggagatagga agccagacta cactgcttac gttgccatga tccctcagtg      900

cataaaggag gaagacaccc cttcagataa tgatagtggc atctgtatga gcccagagtc      960

ctatctgggg tctcctcagc acagcccctc taccaggggc tctccaaata ggagcctccc     1020

atctccaggt gttctctgtg ggtctgcccg tcccaaacct tacgatcctc ctggagagaa     1080

gatggtagca gcaaaagtaa agggtgagaa actggataag aagctgaaaa aaatggagca     1140

aaacaagaca gcagccacta ggtaccgcca gaagaagagg gcggagcagg aggctcttac     1200

tggtgagtgc aaagagctgg aaaagaagaa cgaggctcta aaagagaggg cggattccct     1260

ggccaaggag atccagtacc tgaaagattt gatagaagag gtccgcaagg caagggggaa     1320

gaaaagggtc ccctagttga ggatagtcag gagcgtcaat gtgcttgtac atagagtgct     1380

gtagctgtgt gttccaataa attattttgt agggaaagta aaaaaaaaaa aaaaaaaaa      1439


<210>  2080
<211>  1249
<212>  DNA
<213>  homo sapiens

<400>  2080
gtcccgacgc ctcccgcccc cgcagttcct tggagagctt ggagccgcgc gccggaggga       60

ataggaaagc ttggttacaa cccgggacac ccggagcttc aggatggttc gtactaagac      120

atggaccctg aagaagcact ttgttggcta tcctactaat agtgactttg agttgaagac      180

agctgagctc ccacccttaa aaaatggaga ggtcctgctt gaagctttgt tcctcaccgt      240

ggatccctac atgagagtgg cagccaaaag attgaaggaa ggtgatacaa tgatggggca      300

gcaagtggcc aaagttgtgg aaagtaaaaa tgtagcccta ccaaaaggaa ctattgtact      360

ggcttctcca ggctggacaa cgcactccat ttctgatggg aaagatctgg aaaagctgct      420

gacagagtgg ccagacacaa taccactgtc tttggctctg gggacagttg gcatgccagg      480

cctgactgcc tactttggcc tacttgaaat ctgtggtgtg aagggtggag aaacagtgat      540

ggttaatgca gcagctggag ctgtgggctc agtcgtgggg cagattgcaa agctcaaggg      600

ctgcaaagtt gttggagcag tagggtctga tgaaaaggtt gcctaccttc aaaagcttgg      660

atttgatgtc gtctttaact acaagacggt agagtctttg gaagaaacct tgaagaaagc      720

gtctcctgat ggttatgatt gttattttga taatgtaggt ggagagtttt caaacactgt      780

tatcggccag atgaagaaat ttggaaggat tgccatatgt ggagccatct ctacatataa      840

cagaaccggc ccacttcccc caggcccacc cccagagatt gttatctatc aggagcttcg      900

catggaagct tttgtcgtct accgctggca aggagatgcc cgccaaaaag ctctgaagga      960

cttgctgaaa tgggtcttag agggtaaaat ccagtacaag gaatatatca ttgaaggatt     1020

tgaaaacatg ccagctgcat ttatgggaat gctgaaagga gataatttgg ggaagacaat     1080

agtgaaagca tgaaaaagag gacacatgga atctggaggc catttagatg attagttaat     1140

ttgtttttca ccatttagca aaaatgtata ctaccttaaa tgtcttaaga aatagtactc     1200

ataatgagtt tgagctactt aataaaatac atttaagtgg tatgtaaaa                 1249


<210>  2081
<211>  2521
<212>  DNA
<213>  homo sapiens

<400>  2081
aaaaaccggc cgagccccta aaggtgcgga tgcttattat agatcgacgc gacaccagcg       60

cccggtgcca ggttctcccc tgaggctttt cggagcgagc tcctcaaatc gcatccagat      120

tttcgggtcc gagggaagga ggaccctgcg aaagctgcga cgactatctt cccctggggc      180

catggactcg gacgccagcc tggtgtccag ccgcccgtcg tcgccagagc ccgatgacct      240

ttttctgccg gcccggagta agggcagcag cggcagcgcc ttcactgggg gcaccgtgtc      300

ctcgtccacc ccgagtgact gcccgccgga gctgagcgcc gagctgcgcg gcgctatggg      360

ctctgcgggc gcgcatcctg gggacaagct aggaggcagt ggcttcaagt catcctcgtc      420

cagcacctcg tcgtctacgt cgtcggcggc tgcgtcgtcc accaagaagg acaagaagca      480

aatgacagag ccggagctgc agcagctgcg tctcaagatc aacagccgcg agcgcaagcg      540

catgcacgac ctcaacatcg ccatggatgg cctccgcgag gtcatgccgt acgcacacgg      600

cccttcggtg cgcaagcttt ccaagatcgc cacgctgctg ctggcgcgca actacatcct      660

catgctcacc aactcgctgg aggagatgaa gcgactggtg agcgagatct acgggggcca      720

ccacgctggc ttccacccgt cggcctgcgg cggcctggcg cactccgcgc ccctgcccgc      780

cgccaccgcg cacccggcag cagcagcgca cgccgcacat caccccgcgg tgcaccaccc      840

catcctgccg cccgccgccg cagcggctgc tgccgccgct gcagccgcgg ctgtgtccag      900

cgcctctctg cccggatccg ggctgccgtc ggtcggctcc atccgtccac cgcacggcct      960

actcaagtct ccgtctgctg ccgcggccgc cccgctgggg ggcgggggcg gcggcagtgg     1020

ggcgagcggg ggcttccagc actggggcgg catgccctgc ccctgcagca tgtgccaggt     1080

gccgccgccg caccaccacg tgtcggctat gggcgccggc agcctgccgc gcctcacctc     1140

cgacgccaag tgagccgact ggcgccggcg cgttctggcg acaggggagc caggggccgc     1200

ggggaagcga ggactggcct gcgctgggct cgggagctct gtcgcgagga ggggcgcagg     1260

accatggact gggggtgggg catggtgggg attccagcat ctgcgaaccc aagcaatggg     1320

ggcgcccaca gagcagtggg gagtgagggg atgttctctc cgggacctga tcgagcgctg     1380

tctggcttta acctgagctg gtccagtaga catcgtttta tgaaaaggta ccgctgtgtg     1440

cattcctcac tagaactcat ccgacccccg acccccacct ccgggaaaag attctaaaaa     1500

cttctttccc tgagagcgtg gcctgacttg cagactcggc ttgggcagca cttcgggggg     1560

ggagggggtg ttatgggagg gggacacatt ggggccttgc tcctcttcct cctttcttgg     1620

cgggtgggag actccgggta gccgcactgc agaagcaaca gcccgaccgc gccctccagg     1680

gtcgtccctg gcccaaggcc aggggccaca agttagttgg aagccggcgt tcggtatcag     1740

aagcgctgat ggtcatatcc aatctcaata tctgggtcaa tccacaccct cttagaactg     1800

tggccgttcc tccctgtctc tcgttgattt gggagaatat ggttttctaa taaatctgtg     1860

gatgttcctt cttcaacagt atgagcaagt ttatagacat tcagagtaga accacttgtg     1920

gattggaata acccaaaact gccgatttca ggggcgggtg cattgtagtt attattttaa     1980

aatagaaact accccaccga ctcatctttc cttctctaag cacaaagtga tttggttatt     2040

ttggtacctg agaacgtaac agaattaaaa ggcagttgct gtggaaacag tttgggttat     2100

ttgggggttc tgttggcttt ttaaaatttt cttttttgga tgtgtaaatt tatcaatgat     2160

gaggtaagtg cgcaatgcta agctgtttgc tcacgtgact gccagcccca tcggagtcta     2220

agccggcttt cctctatttt ggtttatttt tgccacgttt aacacaaatg gtaaactcct     2280

ccacgtgctt cctgcgttcc gtgcaagccg cctcggcgct gcctgcgttg caaactgggc     2340

tttgtagcgt ctgccgtgta acacccttcc tctgatcgca ccgcccctcg cagagagtgt     2400

atcatctgtt ttatttttgt aaaaacaaag tgctaaataa tatttattac ttgtttggtt     2460

gcaaaaacgg aataaatgac tgagtgttga gattttaaat aaaatttaaa gtaaaaaaaa     2520

a                                                                     2521


<210>  2082
<211>  2099
<212>  DNA
<213>  homo sapiens

<400>  2082
ctcttcaatc tcagcacctc caagggtcag cacctcccct ccggctccct ccgctaccgc       60

gggccggaac ttttgtcgat aggaacgggt ttgcacattt gcaatggatt ttggataaac      120

aagatctgtt gaaggagcgc caaaaggatt taaagtttct ctcagaggaa gaatattgga      180

agttacaaat attttttaca aatgttatcc aagcattagg tgaacatctt aaattaagac      240

aacaagttat tgccactgct acggtatatt tcaagagatt ctatgccagg tattctctga      300

aaagtataga tcctgtatta atggctccta catgtgtgtt tttggcatcc aaagtagagg      360

aatttggagt agtttcaaat acaagattga ttgctgctgc tacttctgta ttaaaaacta      420

gattttcata tgcctttcca aaggaatttc cttataggat gaatcatata ttagaatgtg      480

aattctatct gttagaacta atggattgtt gcttgatagt gtatcatcct tatagacctt      540

tgctccagta tgtgcaggac atgggccaag aagacatgtt gcttcccctt gcatggagga      600

tagtgaatga tacctacaga acggatcttt gcctactgta tcctcctttc atgatagctt      660

tagcttgcct acatgtagcc tgtgttgtac agcagaaaga tgccaggcaa tggtttgctg      720

agctttctgt ggatatggaa aagattttgg aaataatcag ggttatttta aaactatatg      780

agcagtggaa gaatttcgat gagagaaaag agatggcaac cattcttagt aagatgccaa      840

aaccaaaacc acctccaaac agtgaaggag agcagggtcc aaatggaagt cagaactcta      900

gctacagcca atcttaaaac attccgaaga attccatagt ggaccacttg gaaataaacc      960

attggacaga tttcagtaat gtcttcagtg gaacacaaat gaaaatgaat agcttgtttc     1020

tgtcaagcat attggaaagt gattttattt ttgcaaaata agtttttctt taatatgatt     1080

ctagtacata attgattaaa atctcttgat tataaatgtt tggaaaggtt ctaaggggac     1140

ctacagacag acatacatag acatttcaaa attaatagct tttgattagt ataatatttc     1200

ttaatttgga taataaaaat tgtagctttt tattaagcca ggaaacatga agcataattt     1260

gtttaaaatt ctctttggtc attgagggac caaaaaagga cgtaaaattt acagtcaatc     1320

tatgagggtt tttttccctc cataagttta actttaaaac tgtatttaag gaatcaaatc     1380

ttacaaaatc ctggaagatt ttggtaatga tgttgataat ttcagggaaa ttaatcaagt     1440

acctatattg atttaaaagt gtattttatt cagtagtttg aggatcttgc catggaagat     1500

actagcccag cctagcagaa aagtgcaata tgtatagcat actttgacat tttaaacatg     1560

atagtccata accattttga aatgctgggc aaactacatg aagttattta taattaattc     1620

acagctaatc aggcattttg aaagcttaat tggattcaaa aaccataatg ttggaatttg     1680

gtaaaatttt aatgttgatt tttactgtga aaaggttttt ataagatata cacaccctag     1740

tttaatgttg tgtcttggtg tggatttaca gatttactac aggtattctg aaccaggaac     1800

acaatcaggt ttcaggccag tttgatactg gctgtcctta attctaatat gagagtagga     1860

catcatacta aatgttatgt cagtgggact gtactgtctg tggaacttag caaattaatc     1920

attttcttca gacttgaagg agagtgataa ataaaatttg gagtcatagg atattgatgc     1980

acaatttaag gattaaacat ttttaatcaa ttgtggatga tggcttatta aatgttgact     2040

tcctagtata aaactgcaag aataaaagta acttctccag ctgtaaaaaa aaaaaaaaa      2099


<210>  2083
<211>  2019
<212>  DNA
<213>  homo sapiens

<400>  2083
gaaaaggcgg aggcggcggc ccctccggct cccactgcct cccccgccgc accccctccc       60

caccttccgc acccgccaaa cttgatgtga ccctggcccg acgcggaggc tgcccctctc      120

actgccccgt gggtcccccg ccacccgctc cgcacccgcg agcgcaccgc tccccgcgcc      180

ccttcccact tcccgcgggg ccggcgccgc gctcgccctc gcgttccttc ccgccgcccc      240

ctcccccgca ccatgagcaa cctgaagccg gacggcgagc acggcggcag caccggcacc      300

ggctccggcg cgggctccgg cggcgccctg gaggaggagg tccggacact gtttgtcagc      360

ggcctccctg tggacattaa acccagagaa ctctacttgc tcttccggcc gttcaagggg      420

tatgaagggt ccctgatcaa gctcactgca agacagcctg ttggttttgt gatctttgac      480

agccgtgcag gagcagaagc ggccaagaat gcgctgaacg gtattcgctt tgatcccgaa      540

aatccacaga ctctgaggct agagtttgcc aaagccaaca ccaagatggc caagagcaag      600

ctaatggcaa ctccaaatcc cagcaacgtg caccccgccc taggagcaca cttcatcgca      660

cgggacccct atgacctgat gggggctgct ctgatccctg catccccaga ggcctgggcc      720

ccctaccctt tgtacaccac agagctgacc ccagccatct cccatgctgc gttcacctac      780

ccaactgcca ctgccgctgc cgccgccctc cacgctcagg tgcgctggta cccttcctct      840

gacaccaccc agcaaggatg gaagtaccgt cagttctgtt agtttttcag tctggtcacc      900

ggggaggtgg ttctggtaat ctgtggtggt gccgggacag gcgccccgag ttcccactgc      960

ccccgggcgg cctgcacaga gctgctgccc tccagagact gtgaatccca agcctgactc     1020

agtggactgc ttcctgttcc cctccctcct cttcctcacc ttgttctgca ccctcaagcc     1080

tttctccaat gcctcccagg aggatttggg gactttctcc ctggggcgcc cagatccagc     1140

tcggaggcct cactgggacc tggcaaggcc tgacctcccg cccaaacttg cttctgtagc     1200

tccccctcga ggaagtgagg tgtttaattt tgcatgtttt ctggcatgaa ttaagacact     1260

tatacttgta tatatgagtg tacagtttgt tctcacactg tcaccatagc gacaggtcct     1320

ggctcccagt ggttcatcct gcctgcccct ctctcctcgc cccgcccctg cacccacccc     1380

gcttcaggga ggcccaagtt ccgtggcccc acacgcttcc aggctcagct cccacctcca     1440

cccaacagat agatggggtt tgctttttca tttcacatgg ggctcctccg ctcctgcctt     1500

ctcggatggg ccaacagtcg taagaaagcc ctctctgccc gttctgttca cctctccaca     1560

gcgcaccccg cccgccgctg ctcctcattc tttccaaacc tcgaaaccaa ccaaaacgtg     1620

agaagtattt ttgtaccctg tgtaacaaaa tatttatgca tcataaagga tttttcatgt     1680

gcgtaccatt aattattaaa gcgacctcgt tcgccctgtc agataagttt aatgtttagt     1740

ttgaggcatg aagaagaaaa gggtttccat tcttcagcag tacgcctttg tgtctggcat     1800

ttgtttaaga aaatgaaatg aaggaaacac tgtgcaatgt tttttgtttt gagcatatca     1860

gtgctttact gtcagccgca gctgtgaccg tctggccatt tcagacttgg gagatgaggc     1920

ggctgttgtc attgctgatc ctgtgagaat gtgaaactgg ataatatatg aaatgcaaaa     1980

taaaacaaaa ccaaaaaaaa aaaaaaaaaa aaaaaaaaa                            2019


<210>  2084
<211>  8005
<212>  DNA
<213>  homo sapiens

<400>  2084
ggggattggc ggagcgcgag gagagaatgt gacaagtgcc ggctcggcgg ccgccggggg       60

aggccgcgcg cacctgtccc tgcccgtctc gcgccgcccg cggccgctcg gacgcgcgca      120

gagccgcccc ccgccgctgc cgccgcgtgc gcccgcgaac atgacttctg ccttcaagct      180

ggatttcctc ccggacatga tggtcgaggg ccgcctgctc gttcctgaca gaattaacgg      240

cacagccaac aagatgaacg gagctttgga tcactcagac caaccagacc cagatgccat      300

taagatgttt gtcggacaga tcccccggtc atggtcggaa aaggagctga aagaactttt      360

tgagccttac ggagccgtct accagatcaa cgtcctccgg gaccggagtc agaaccctcc      420

gcagagtaaa ggttgttgtt tcgtaacatt ttatacaaga aaagctgcac ttgaggccca      480

gaatgcactg cacaatatta aaactttacc tgggatgcat catcccattc agatgaaacc      540

tgcagatagt gaaaagtcca acgctgtgga agacagaaaa ttgttcatag gaatggtatc      600

gaagaaatgt aatgagaacg acatcagggt gatgttctct ccatttggcc agatagaaga      660

atgccggatc ctccggggac ctgatgggct gagtcgaggc tgtgcgtttg tcacattttc      720

tacaagggca atggcacaga atgcaatcaa agccatgcat cagtctcaga ccatggaggg      780

ctgctcttca cctatcgtgg tgaagtttgc tgacactcag aaggacaaag agcaaaggcg      840

cctccagcag cagctcgctc agcagatgca gcagctcaac actgccacct gggggaacct      900

gacagggctg ggcggactga ccccacagta tctggcgctc ctgcagcagg ccacctcctc      960

cagcaacctg ggtgcgttca gcggcattca acaaatggca ggcatgaatg ctttacagtt     1020

gcagaacctg gcgacgctgg ctgctgctgc agctgcggcc cagacctcag ccaccagcac     1080

caatgcaaac cctctctcta ccacgagcag cgccctggga gccctcacga gtcccgtggc     1140

tgcttcaacc cccaactcca ctgctggtgc agccatgaac tccttgacct ctctcgggac     1200

tctgcaagga ctggctggag ccactgttgg actgaataat attaatgcac tagcagttgc     1260

tcaaatgctc tcaggtatgg cggctctgaa tggaggactt ggcgccacag gcttgacgaa     1320

tggcacggct ggcaccatgg acgccctcac ccaggcctac tcaggaattc aacagtacgc     1380

agccgccgcg ctgcccactc tgtacagcca gagcctgctg cagcagcaga gcgctgcagg     1440

cagccagaag gaaggtccag agggggcaaa cctctttatt taccaccttc cacaggaatt     1500

tggagaccag gacattctgc agatgttcat gccttttgga aatgttatct ctgctaaagt     1560

cttcattgac aaacagacca atctgagcaa gtgctttggt tttgttagct acgacaatcc     1620

agtctctgca caagctgcta tccaagctat gaatggcttt cagatcggca tgaaacgctt     1680

gaaggtgcag ctgaagcgtt ccaaaaacga cagcaaacct tactgatcct aaccccagag     1740

gctccctgct ctcattttag ctttcttagg acatcttcat gcccgttagt tcatcgtttg     1800

cctagcatgt ccctgtggcg tctcaaaaaa aagtttcatc gtcccgtcat tgtttctgat     1860

gtctttctga cctcacatca tatttggttc tcctactgac ctttgatcta gtttgacctt     1920

tgaaatttgc atgtgacctc atctagctat gaattctggg aagtcaatgt gaaaaacatt     1980

gctgcattca tgcaagactg aaatttatta ttagacaaat tcattataga aaaaacctgt     2040

ggcaaaaacg tttctttctt attttttttc ttttcctaaa acagacttga aagtattata     2100

cagggattgg cattcttccc ggtcactggt aacaatagca atatgtgtcc agggacacag     2160

aatgttggtt tctaacagac tacttccaaa aacagtttga gaaaaaaact gtctgatttt     2220

aagtctctag aggtctgtaa tagtttttac atttttcagg cagtgtaaag ttttttgata     2280

aggccatttt aggtggctca ctttctcatt aagatatata tatagaacca ctttttgtag     2340

attagtataa gaaaaatatt taccctgttt tggggcaaat gctacctatt tgtgtcacct     2400

tttgctgaac tcacagttag acaatccatg gtttaatgca catgaaatta cctatatttt     2460

atactgtttc aatgtacagg agaaaggtta ctgtaaactg tgttatgttg gtgcttctgt     2520

gaattaagtt gtggtttcat catgagtctt aatgttcttt gttgataaga caagtttaga     2580

attggtttac ttaatacaaa aaaaaaaaaa agaatttcaa aaaaaaaagt tgtttgctta     2640

aaaaaaattt catgtgaggg aaaaaaaaaa aacctattcc agaataagtt ttgtgttggc     2700

ttgtgaagca ttgatgtcat tttttttaat tgtggactat ttagatgtgt ttgtgttcag     2760

caaaatgtga tctgtttttt tcttttaaag aaaaaaagtg aaaatatata gtgccaaatt     2820

ccaaaggtac ttccttccta gagcttcagt gtgtttcttg tgagaagtaa tttgataaca     2880

tgggtatttt attatgtgtt ttgtataaat ccctaatatt taaaaaaaaa aacaaaacaa     2940

aaaaaggtta caaagtttgt taacttgcta tcctgtggtc ttgttgcctg aaattgttat     3000

tgtttgttat ttctctctga tgttttttgt aagacattgt ataagtgccc atgtcccact     3060

tttttaacca ctccgcacat cagtgctgtg aaggcaacct caccatgtat tttcttcata     3120

atctatggaa acctctaagg tgagaaagtt ttgaactttt aaccctttct acccagagct     3180

atctggaatg ttgatgactt tttatactgt catgatttga gtttgttttg gggtgtttcc     3240

aatttggatt tttttccctg catctatcct ctaagttgtt tcggtttgac tactttgttc     3300

tttggttaag atccaaaaga aaacagaaaa caattccacg aggccaatct aaagggaaaa     3360

aatcctacac tacttttact acttttgatt atttctcatt tttgggaaaa gaattcctaa     3420

tgtgctacta gaattccttc ttcagtttta acgagtaatt ggataaaccc tgagggaaaa     3480

cggaggtaga ttcagcacct aacaatcctg tatgcttttg agatcacgtt tagtgctatg     3540

tcctagtcta gaatattttc atataccttg cagtaaaacg actttgtggc aggacagtct     3600

cttgaggggt tttgtttctg tttcctaaat actcctaaat aatatttcta atcagccatt     3660

atgctggggc atctctgatc ccagtaggta cctctgaata taccaggtgt ctggagttag     3720

aagcccatag ccctttccca gcctttttgg tttttttaat tgaacacatt tcatctaagt     3780

aaagctcagt tctttatcac aatttactga ccaaatacct agcaccagtt cctgctgcca     3840

ctttttaaag tgccatatga ctttctacga acaggtacct tgctgtcttg acaaatccta     3900

atgtcacgcc tacagcccca acacaagctc cagtcttcct cttcggcatg ccctggaagc     3960

ttcttggcct cagctcccct tccccgctca gcaccctgtt aggatcagtg tgtgtggatg     4020

ggatagccct gggatggaaa ggactagcct ctactgatgc aaaaaaacaa aaagcaacac     4080

aaacgtttcc ttcttatagc acatgcactt ccttacaatg acatgatttg tattatcctc     4140

acatgtgttt actactgctg gggccttcct tcatcctctg agggctattt tgtactttct     4200

gcagcaatca gcttaataac aacacttatt gcacctgtct ctctctgaga acacggtgtg     4260

tctcgacacg taccacgtac gtggaaacac aagagcccac cacttgaatt tctaagacca     4320

tttcattctg aaacttctta tcaattacct aaatctcaac gaaaaacaat ttactgaagc     4380

cgactcccct ccccatctcc ctctcaacct caacccacct gcatgcatct cccccagagg     4440

aaacactgag ggtaggggac aggaggctca ggacgcgccc tctgaatcga gtgtttcttc     4500

ttcacaagtc accaagagag gacatgaggg ggaaagtcct tttttgccct tctccaaaaa     4560

ataaccttcc acagagacaa actgtccttc tatccacttt tatcttttaa taaatatcaa     4620

aaggaaaaag ctgcaagggt gcaaagggcc tgtgccagaa gaaaacacac acagggaaac     4680

cgcttttttt aatcaattgt agagaatagt catttttaat ctaaattaga gaattgtgat     4740

acaatggcag tcctcaaagg cgtaacgagt tcatctttct ttcaccatag gggttatagt     4800

tggcttgtgc tactctggaa tcattttact gtttgttttt attatcttaa gtgctaatta     4860

aaaaaaaaat aaaattttaa aaaaacctgt agtttcatta cctttttgaa taatgtcata     4920

caaaaaatgt atttgttttt ttgtgctgtg agaattgatg tttgtagatt aataatcatt     4980

ttgtttagaa ttacaaaata gtttttaaat attgtctgag aaaagccaaa gttaatgcaa     5040

cctagtggaa actgtaagac catttgagta ttgtttgttt tattgatgca tttggatttt     5100

gttgtttgat ggaatttgag ccaaaaaaaa aatacgcagg ctttcctatt tctacaactg     5160

attgtactta tgcattttgt accagtggaa ctttttatac tggagattaa aaaaaaaatg     5220

gaaatttttg tggcttgctc tggtgggccc ctgacaatga ctgatttcaa gtttgatttc     5280

gggttgattg attgattgat tgatagaaag aaagttgctt ttcttttgag aattaaaaac     5340

tttggcttga tttctttttt ccctttgctt atatctagca ttagaatttt gtcttaaaat     5400

aacagcggta agtttcactt tttattctgt attgtgcagt tacacaataa ggtaattaga     5460

tttagaagta ctcagtcact ttaagtggat aaatgtatta gttaaaactt tagggtttgc     5520

ttttttgctg tttagatcaa agttttttct gattcttctg tcctcattgt gaacataacc     5580

gtgtagttga aacagtcaaa cttatttttg taatgtatgt tattgtgtga tgcagttttt     5640

tgcttctgtc tccaatatta aaccattttc ctaatacttg tttctctctc tgcgtgttgt     5700

attgttggta gtcattatat gttggtgata catctgcaca cctcactgtt tcacgtatct     5760

gtttttttct ctatgttgtg taaaaagata cagtcgattc cacttaagtg aatatctgat     5820

ttggggaaga ggaaactgca cagcagccac ctttgattta tgtacaaccg cccacttgaa     5880

ctcctgcttc caagatttat acactttttt cctacagttc acctcagtaa ctgcctttgg     5940

ggttggattt gccaaggtgt tttacggtct tttgaccaca caggttaatt tccccttctc     6000

tcccctccct catgagtcta tccacgcagt tcttaacata cattccaaac tgctgcgggg     6060

tttcctctcc acacccacga ggccaaaccc gcatcattac agtccaactc ttcttagaca     6120

ctaatcactt tctaaaagaa gtgagttctc cagggaagaa aaatcaactt agccagtgaa     6180

aagggttaaa cttaagtcta ttatttgttg ccctcaatca aaagatatgt atagaaaagt     6240

catttaaatt atttatttct acaagctaat tgaatccagg agcagcttta attattaaca     6300

ctaacggaag agaaaagaag tatttccaag ggctcaaatg gaagctgtac tcagtccggt     6360

ggaggcaggg ggaggtaaag tttctcacac tcaagtcgtc ttcatagttt actgtccttt     6420

tccaaacaaa agctaataac gccatacgca tccacacact ccctcctgga tgaacctaag     6480

tctcgtcccc actgtcaccc caaggccagt tatcaaaaac tgttccttct ctgccctcaa     6540

agactgaagc cgcaggccct gttctgcctc tgctcaggaa tctgattgct cttaaagtgc     6600

tcttacaaga ttccgtcgat gtttgctccc tctgtcttat ctctccttcc agtattttca     6660

gacgcacaag ctctgactca ggccacccag cacctggcag ccttcctctg cgtgccagtg     6720

aaatctctcc cagtaggtgc tcaggctctt caccctctcg ttgcagcagc ccctctggcc     6780

cgagattgta ttttctagtc tgctcaagaa cagaggggcc tggcgaggtg gaggaaggga     6840

ggctccctcc ccggggctgg ccgcctcagt gatggtgatg ccaccagctc cagcctgcac     6900

ggatggagct cacttcctac catcacttct gctttcagtc tcctcatagc cttcggcagt     6960

ctcctctgaa aacacactgc ctacgttagt gggaaaggat ggctaagggt gtgatttctt     7020

tttattaggg aggtgggagg gggatgttgg gaggcatggg gggtgattaa attatcattt     7080

ccaaggtgca agtgtttatt tttcaaatct ataagtacat agttccacca ttttggcaca     7140

agacaaaata ctcatgctaa gcaaaggaag agaaagacaa agccagtttt tgttgctttt     7200

ctaaagcaac aaataattct ccaaagaagg ggatgaaaat gctagttcct ttaagcactt     7260

actgactgta aagttggtcc ctgcttaaat tcatacccat agttttgagt cggtatgaca     7320

ccactgcagt gtgagcaagg tgaatccgtg tgccatgcat ggaccacctt gggataccgc     7380

agcaccatca acatccgcct tgctgatgga agccacacac gctgcccagc ccacagcagt     7440

cgcacgcagc cgatgggctc ggactcttag ctggcaggct aggacacaca gtgaacatta     7500

atgtactgtg aatcgttcct gataagtgaa taaaacattg tgaccaaaca atcagcttat     7560

tcacttatca ggaatcgact gttctgctaa tttgctgttg ttgtttttca tctctgttgt     7620

agttcactat ttttgctgtg ttctgttttc tcctctcatg cttgggcaaa tcactgggaa     7680

tattatcttc atgtgaccat gaaacgtttc tattgagtga aaatgatatc ttaacaaaat     7740

ctatgcactt gctatcagga acacaatact ggatgtgtct tatatatatt gaactatata     7800

gtactcgatt tcttaaataa agcttaagaa aggactctgt tgtgtgtaaa gttaatgtga     7860

ttatttttca aagcagtgtt tctaaggggt atttttgttc ttttaagtct tgagtgatac     7920

aggatatttt tcattaaaat tatatcactg gctttatgac ttaatattca ataaattgac     7980

tttggaaaca aaaaaaaaaa aaaaa                                           8005


<210>  2085
<211>  4392
<212>  DNA
<213>  homo sapiens

<400>  2085
acagttgccc cggtgaggga aacggaggcg ccatagccac ggtagtcgtg gcgaccaagc       60

aacccggcaa cgcgagtcaa caacaacaac cgcccggccg acccccaccc ccacccccca      120

ggcccggccc ggggacccca gcacgtcccg tccccttccc aacatcgact ccgagacctc      180

cgaaaagcgt ttccgcagac agaagtgggg agaagcggag gaattaaaaa aaaaaaaaag      240

ccttatttat tatcattttc cccaccgttg gcatggcaac acaggcgtat actgagctac      300

aggcagcccc gccaccatcc cagccgccac aggccccgcc acaagcccag ccccagccgc      360

caccgccacc acccccagcg gcaccccagc ccccgcagcc acccaccgct gctgccaccc      420

ctcagcccca atatgtcacc gagctgcaga gcccccagcc ccaggcacag ccaccgggtg      480

gccagaagca gtacgtgacg gagctcccgg ctgtacccgc accctcgcag ccaaccggtg      540

cacccacccc ttcgcctgca ccccagcagt acatcgtggt cactgtctct gaaggtgcca      600

tgcgggccag cgagacagtg tcggaggcca gccccggctc caccgccagc cagaccggcg      660

ttcctactca ggtggttcag caggtgcagg gcacccagca gcggctgctg gtccagacga      720

gcgtgcaggc caagccaggc cacgtgtcgc ccctccagct gaccaacatc caagtgcccc      780

agcaggctct tcccacgcag cgtctggtgg tgcagagcgc agccccaggc agcaaaggtg      840

gccaggtctc cctgacggtc catggtaccc agcaggtgca ctcgccccca gagcagtcgc      900

cggtgcaggc caacagctct tccagcaaga cagccggggc ccccacgggc acagtgccac      960

agcagctgca ggtccacggc gtccagcaga gtgtccccgt cacccaagag agatctgtgg     1020

tccaggccac tccacaagcg cccaaacccg gcccggtgca gccgctgacc gtgcagggcc     1080

tccagccagt ccacgtggct caagaggtgc agcagctcca gcaggtgccc gtcccacacg     1140

tgtactccag ccaggtgcag tatgtggagg gcggcgatgc cagctacacg gccagtgcca     1200

tccgttccag cacctactcc tatcccgaga cgccgctgta cacgcagacg gcaagcacca     1260

gctactacga ggccgcaggc acggccaccc aggtcagcac ccccgccacc tcccaggcgg     1320

tggccagcag tggctccatg cccatgtacg tgtccggcag ccaggtcgtc gccagctcca     1380

ccagcactgg ggctggggcc agcaacagca gcggaggtgg tggcagtggt ggtggcggcg     1440

gcggcggggg aggcggtggc gggggtggca gtggcagcac cggaggcggc ggcagcggag     1500

caggcaccta cgtgatccaa ggcggctaca tgctgggcag tgccagccag tcttactctc     1560

acaccacccg tgcctcgcca gccacggtcc agtggctcct ggacaactat gagacggctg     1620

agggcgtgag tctgccacgg agcaccctct actgccacta cttactgcac tgccaggagc     1680

agaagctgga gcccgtcaac gccgcctcct tcggcaagct catccgctcc gtcttcatgg     1740

gcctgcgaac ccgccgtctg ggcaccaggg gcaactccaa gtaccactac tatggcctgc     1800

gcatcaaggc cagctcaccc ctgctgcggc tgatggagga ccagcagcac atggccatgc     1860

ggggccagcc cttctcgcag aagcagaggc tcaagcccat ccagaagatg gaaggcatga     1920

ccaacggcgt ggcggtgggg cagcagccga gcacggggct gtcggacatc agcgcccagg     1980

tgcagcagta ccagcaattt ttggatgcct ctcggagcct ccctgacttc acagagctcg     2040

acctccaggg caaggtgctg cctgagggcg tcgggcccgg ggacatcaaa gccttccagg     2100

tcctgtaccg ggaacactgt gaggccattg tcgacgtcat ggtgaacctg cagttcaccc     2160

tggtggagac gctgtggaag accttctgga ggtacaacct cagccagccc agtgaggcgc     2220

caccgctggc tgtacatgac gaggccgaga agcgactgcc caaagccatc ctggtgctcc     2280

tctccaagtt cgagcccgtg ctccaatgga ccaagcactg tgacaacgtg ctgtaccagg     2340

gcctggtgga aatcctcatt cccgacgtgc tgcggcccat ccccagtgcc ttgacccaag     2400

cgatccggaa ctttgccaag agcctggaga gctggctcac ccacgccatg gtcaacatcc     2460

ccgaggagat gctgcgggtg aaggtggccg cggctggcgc cttcgcgcag acactgcggc     2520

gctacacgtc gctcaaccac ctggcgcagg cggcgcgcgc tgtgctgcag aacaccgcac     2580

agatcaacca gatgctgagc gacctcaacc gcgtggactt cgccaacgtg caggagcagg     2640

cctcgtgggt gtgccgctgc gaggaccgcg tggtgcagcg gctggagcag gacttcaagg     2700

tgacgctgca gcagcagaac tcgctggagc agtgggcggc ctggctggac ggcgtggtga     2760

gccaggtgct caagccctac cagggcagcg ccggcttccc caaggccgcc aagctcttcc     2820

tcctcaagtg gtccttctac agctccatgg tgatccggga cctgaccctg cgcagcgccg     2880

ccagcttcgg ttccttccac ctcatccggc tgctctacga cgagtacatg tactacctga     2940

tcgagcaccg cgtagcccag gccaagggcg agacccccat cgccgtcatg ggcgagttcg     3000

ccaatctggc cacctccctg aaccccctgg accccgacaa agacgaggag gaagaagagg     3060

aggaggagag cgaggacgag ctgccgcagg acatctcact ggcggctggc ggcgagtcac     3120

ccgcgctggg cccggagacc ctggagccgc cggccaagct ggcgcggact gacgcgcgcg     3180

gcctcttcgt gcaggcgctg ccctccagct aagcccttgg cctccccgcc ccacccgccc     3240

ccgccacccc tccacgccag ggtccctcaa agcttctgtg gcttcgtggt cactgctcca     3300

gcctcagcca gggcagggag ggggactccg agacagggaa gaccggggcc ctcctccctt     3360

atggggccgg cacaatcagt gggctgggcg gagccgcagc tgcaaactct gacacaaaag     3420

acgtgcctta aggaacccgc cgcgtgccca ggtgccccgc ggggcatcca gctcggcccc     3480

ttggccgccc ccctcccagg ccccagcgtc ttctccccag ccccgtcctc ccaccacccc     3540

agggggcagg caggcaggcc ccctcccgtg cgaaactgtt aacttattca gctcgctggc     3600

tttgcacagc ctgtcctggg cccagccctg agccccgggc cggcgcaggt gggcgtcacc     3660

tggggactcc ccactgtcag cagcagcccc gggacaccct acccccagca accccactgc     3720

ttccccttct tggtattaag tgcaattaaa gccgtgggtg tcgcatcttc tccagcgctg     3780

ggccctccct tgcccccaag ctcaagaagg gggcactgcc cggcccggct gtgaggaggg     3840

cggcaggggg cacggcctcc agcttccaaa gagcagcgag ccgcggagcc ggggagtgcc     3900

cacagacccc agcccccgcg cccccgccct ccgccgctgg tttgtaatgg aaccttttct     3960

gtgcccctat cttcccggag accacgcttc tcctccgtgc cgtgcgaccc ccaccccatg     4020

actattgtgc gattcgtgag cgccgcccga gcggagttgg taacttgttg ggtttttttc     4080

caaccatcat ggccttatct gttccagttt tctcagtgtt ttcagcctgt gagatagatg     4140

tttatggcaa gaaaaaggaa aaaaaaatgg aaatctgacc tattgtataa aaatcactat     4200

tttgtgtgct ccgcgtgcta tagcttttgg ggcggccctg cccagtcccc gtgcccacgg     4260

ggctccctct cccggtggtg aaagtgtcca cacgtgtggt agtctagtgt gccgagctgt     4320

tttctacctt tttgtagtct ttcttaaaac aataaattcc gctgtgatat ttgcctaaaa     4380

aaaaaaaaaa aa                                                         4392


<210>  2086
<211>  7658
<212>  DNA
<213>  homo sapiens

<400>  2086
gctcactcgc tcaactcggc gccgccgcgg ccccacgctc cgggcccgtc ctcgaggcgc       60

gcggcgcggg gcgcgggcgc cggggcctga ggcggcgggc gacgcccggg ggcctgacgg      120

ccggccccgc gccatggtgt gagcgccgcc gcccgtgcac gctccgtccg ccctccgcgc      180

ggcccggccg gcagagagcc ccgagcggcc cgagagcgca gccgagcccg ccgccgccgc      240

ccgcggcccc gcgaggagag taccgggccg gctcggctgc cgcgcgagga gcgcggtcgg      300

cggcctggtc tgcggctgag atacacagag cgacagagac atttattgtt atttgttttt      360

tggtggcaaa aagggaaaat ggcgaacgac tcccctgcaa aaagtctggt ggacatcgac      420

ctctcctccc tgcgggatcc tgctgggatt tttgagctgg tggaagtggt tggaaatggc      480

acctatggac aagtctataa gggtcgacat gttaaaacgg gtcagttggc agccatcaaa      540

gttatggatg tcactgagga tgaagaggaa gaaatcaaac tggagataaa tatgctaaag      600

aaatactctc atcacagaaa cattgcaaca tattatggtg ctttcatcaa aaagagccct      660

ccaggacatg atgaccaact ctggcttgtt atggagttct gtggggctgg gtccattaca      720

gaccttgtga agaacaccaa agggaacaca ctcaaagaag actggatcgc ttacatctcc      780

agagaaatcc tgaggggact ggcacatctt cacattcatc atgtgattca ccgggatatc      840

aagggccaga atgtgttgct gactgagaat gcagaggtga aacttgttga ctttggtgtg      900

agtgctcagc tggacaggac tgtggggcgg agaaatacgt tcataggcac tccctactgg      960

atggctcctg aggtcatcgc ctgtgatgag aacccagatg ccacctatga ttacagaagt     1020

gatctttggt cttgtggcat tacagccatt gagatggcag aaggtgctcc ccctctctgt     1080

gacatgcatc caatgagagc actgtttctc attcccagaa accctcctcc ccggctgaag     1140

tcaaaaaaat ggtcgaagaa gttttttagt tttatagaag ggtgcctggt gaagaattac     1200

atgcagcggc cctctacaga gcagcttttg aaacatcctt ttataaggga tcagccaaat     1260

gaaaggcaag ttagaatcca gcttaaggat catatagatc gtaccaggaa gaagagaggc     1320

gagaaagatg aaactgagta tgagtacagt gggagtgagg aagaagagga ggaagtgcct     1380

gaacaggaag gagagccaag ttccattgtg aacgtgcctg gtgagtctac tcttcgccga     1440

gatttcctga gactgcagca ggagaacaag gaacgttccg aggctcttcg gagacaacag     1500

ttactacagg agcaacagct ccgggagcag gaagaatata aaaggcaact gctggcagag     1560

agacagaagc ggattgagca gcagaaagaa cagaggcgac ggctagaaga gcaacaaagg     1620

agagagcggg aagctagaag gcagcaggaa cgtgaacagc gaaggagaga acaagaagaa     1680

aagaggcgtc tagaggagtt ggagagaagg cgcaaagaag aagaggagag gagacgggca     1740

gaagaagaaa agaggagagt tgaaagagaa caggagtata tcaggcgaca gctagaagag     1800

gagcagcggc acttggaagt ccttcagcag cagctgctcc aggagcaggc catgttactg     1860

catgaccata ggaggccgca cccgcagcac tcgcagcagc cgccaccacc gcagcaggaa     1920

aggagcaagc caagcttcca tgctcccgag cccaaagccc actacgagcc tgctgaccga     1980

gcgcgagagg tggaagatag atttaggaaa actaaccaca gctcccctga agcccagtct     2040

aagcagacag gcagagtatt ggagccacca gtgccttccc gatcagagtc tttttccaat     2100

ggcaactccg agtctgtgca tcccgccctg cagagaccag cggagccaca ggttcctgtg     2160

agaacaacat ctcgctcccc tgttctgtcc cgtcgagatt ccccactgca gggcagtggg     2220

cagcagaata gccaggcagg acagagaaac tccaccagca gtattgagcc caggcttctg     2280

tgggagagag tggagaagct ggtgcccaga cctggcagtg gcagctcctc agggtccagc     2340

aactcaggat cccagcccgg gtctcaccct gggtctcaga gtggctccgg ggaacgcttc     2400

agagtgagat catcatccaa gtctgaaggc tctccatctc agcgcctgga aaatgcagtg     2460

aaaaaacctg aagataaaaa ggaagttttc agacccctca agcctgctga tctgaccgca     2520

ctggccaaag agcttcgagc agtggaagat gtacggccac ctcacaaagt aacggactac     2580

tcctcatcca gtgaggagtc ggggacgacg gatgaggagg acgacgatgt ggagcaggaa     2640

ggggctgacg agtccacctc aggaccagag gacaccagag cagcgtcatc tctgaatttg     2700

agcaatggtg aaacggaatc tgtgaaaacc atgattgtcc atgatgatgt agaaagtgag     2760

ccggccatga ccccatccaa ggagggcact ctaatcgtcc gccagagtac agttgaccaa     2820

aagcgtgcca gccatcatga gagcaatggc tttgccggtc gcattcacct cttgccagat     2880

ctcttacagc aaagccattc ctcctccact tcctccacct cctcctcccc atcctccagc     2940

cagccgacac ccaccatgtc cccacagaca ccccaggaca agctcactgc taatgagact     3000

cagtccgcta gtagcacact ccagaaacac aaatcttcct cctcctttac accttttata     3060

gaccccagat tactacagat ttctccatct agcggaacaa cagtgacatc tgtggtggga     3120

ttttcctgtg atgggatgag accagaagcc ataaggcaag atcctacccg gaaaggctca     3180

gtggtcaatg tgaatcctac caacactagg ccacagagtg acaccccgga gattcgtaaa     3240

tacaagaaga ggtttaactc tgagattctg tgtgctgcct tatggggagt gaatttgcta     3300

gtgggtacag agagtggcct gatgctgctg gacagaagtg gccaagggaa ggtctatcct     3360

cttatcaacc gaagacgatt tcaacaaatg gacgtacttg agggcttgaa tgtcttggtg     3420

acaatatctg gcaaaaagga taagttacgt gtctactatt tgtcctggtt aagaaataaa     3480

atacttcaca atgatccaga agttgagaag aagcagggat ggacaaccgt aggggatttg     3540

gaaggatgtg tacattataa agttgtaaaa tatgaaagaa tcaaatttct ggtgattgct     3600

ttgaagagtt ctgtggaagt ctatgcgtgg gcaccaaagc catatcacaa atttatggcc     3660

tttaagtcat ttggagaatt ggtacataag ccattactgg tggatctcac tgttgaggaa     3720

ggccagaggt tgaaagtgat ctatggatcc tgtgctggat tccatgctgt tgatgtggat     3780

tcaggatcag tctatgacat ttatctacca acacatatcc agtgtagcat caaaccccat     3840

gcaatcatca tcctccccaa tacagatgga atggagcttc tggtgtgcta tgaagatgag     3900

ggggtttatg taaacacata tggaaggatc accaaggatg tagttctaca gtggggagag     3960

atgcctacat cagtagcata tattcgatcc aatcagacaa tgggctgggg agagaaggcc     4020

atagagatcc gatctgtgga aactggtcac ttggatggtg tgttcatgca caaaagggct     4080

caaagactaa aattcttgtg tgaacgcaat gacaaggtgt tctttgcctc tgttcggtct     4140

ggtggcagca gtcaggttta tttcatgacc ttaggcagga cttctcttct gagctggtag     4200

aagcagtgtg atccagggat tactggcctc cagagtcttc aagatcctga gaacttggaa     4260

ttccttgtaa ctggagctcg gagctgcacc gagggcaacc aggacagctg tgtgtgcaga     4320

cctcatgtgt tgggttctct cccctccttc ctgttcctct tatataccag tttatcccca     4380

ttcttttttt ttttcttact ccaaaataaa tcaaggctgc aatgcagctg gtgctgttca     4440

gattctacca tcaggtgcta taagtgtttg ggattgagca tcatactgga aagcaaacac     4500

ctttcctcca gctccagaat tccttgtctc tgaatgactc tgtcttgtgg gtgtctgaca     4560

gtggcgacga tgaacatgcc gttggtttta ttggcagtgg gcacaaggag gtgagaagtg     4620

gtggtaaaag gagcggagtg ctgaagcaga gagcagattt aatatagtaa cattaacagt     4680

gtatttaatt gacatttctt ttttgtaatg tgacgatatg tggacaaaga agaagatgca     4740

ggtttaagaa gttaatattt ataaaatgtg aaagacacag ttactaggat aacttttttg     4800

tgggtggggc ttgggagatg gggtggggtg ggttaagggg tcccattttg tttctttgga     4860

tttggggtgg gggtcctggc caagaactca gtcatttttc tgtgtaccag gttgcctaaa     4920

tcatgtgcag atggttctaa aaaaaaaaaa aaaaaaaaaa aaaaaaggaa aaaaaaaaag     4980

aaaaagaaaa cgtgtgcatt ttgtataatg gccagaactt tgtcgtgtga cagtattagc     5040

actgcctcag ttaaaggttt aatttttgtt taaacctaga cgtgcaacaa aagttttacc     5100

acagtctgca cttgcagaag aaagaaaaaa attcaaacca catgtttatt ttttttttgc     5160

ctacctcatt gttcttaatg cattgagagg tgatttagtt tatatgtttt tggaagaaac     5220

cattaatgtt taatttaatc ttaataccaa aacgaccaga ttgaagtttg acttttattg     5280

tcacaaatca gcaggcacaa gaactgtcca tgaagatggg aaatagcctt aaggctgatg     5340

cagtttactt acaagtttag aaaccagaat gctttgtttt taccagattc accattagag     5400

gttgatgggg caactgcagc ccatgacaca agatctcatt gttctcgatg tagaggggtt     5460

ggtagcagac aggtggttac attagaatag tcacacaaac tgttcagtgt tgcaggaacc     5520

ttttcttggg ggtgggggag tttccctttt ctaaaaatgc aatgcactaa aactatttta     5580

agaatgtagt taattctgct tattcataaa gtgggcatct tctgtgtttt aggtgtaata     5640

tcgaagtcct ggcttttctc gttttctcac ttgctctctt gttctctgtt tttttaaacc     5700

aattttactt tatgaatata ttcatgacat ttgtaataaa tgtcttgaga aagaatttgt     5760

ttcatggctt catggtcatc actcaagctc ccgtaaggat attaccgtct caggaaagga     5820

tcaggactcc atgtcacagt cctgccatct tactttcctc ttgtcgagtt ctgagtggaa     5880

ataactgcat tatggctgct ttaacctcag tcatcaaaag aaacttgctg ttttttaggc     5940

ttgatctttt tcctttgtgg ttaattttcc tgtatattgt gaaaatgggg gattttccct     6000

ctgctcccac ccacctaaac acagcagcca tttgtacctg tttgcttccc atcccacttg     6060

gcacccactc tgacctcttg tcagtttcct gttcctggtt ccatcttttt gaaaaaggcc     6120

ctcctttgag ctacaaacat ctggtaagac aagtacatcc actcatgaat gcagacacag     6180

cagctggtgg ttttgtgtat acctgtaaag acaagctgag aagcttactt tttggggaag     6240

taaaagaaga tggaaatgga tgtttcattt gtatgagttt ggagcagtgc tgaaggccaa     6300

agccgcctac tggtttgtag ttaacctaga gaaggttgaa aaattaatcc tacctttaaa     6360

gggatttgag gtaggctgga ttccatcgcc acaggacttt agttagaatt aaattcctgc     6420

ttgtaattta tatccatgtt taggcttttc ataagatgaa acatgccaca gtgaacacac     6480

tcgtgtacat atcaagagaa gaaggaaagg cacaggtgga gaacagtaaa aggtgggcag     6540

atgtctttga agaaatgctc aatgtctgat gctaagtggg agaaggcaga gaacaaagga     6600

tgtggcataa tggtcttaac attatccaaa gacttgaagc tccatgtctg taagtcaaat     6660

gttacacaaa aaaaaatgca aatggtgttt cattggaatt accaagtgct tagaacttgc     6720

tggctttccc ataggtggta aaggggtctg agctcacacc gagttgtgct tggcttgctt     6780

gtgcagctcc aggcacccgg tgggcactct ggtggtgttt gtggtgaact gaattgaatc     6840

cattgttggg cttaagttac tgaaattgga acaccctttg tccttctcgg cgggggcttc     6900

ctggtctgtg ctttacttgg cttttttcct tcccgtctta gcctcacccc cttgtcaacc     6960

agattgagtt gctatagctt gatgcaggga cccagtgaag tttctccgtt aaagattggg     7020

agtcgtcgaa atgtttagat tcttttagga aaggaattat tttcccccct tttacagggt     7080

agtaacttct ccacagaagt gccaatatgg caaaattaca caagaaaaca gtattgcaat     7140

gacaccatta cataaggaac attgaactgt tagaggagtg ctcttccaaa caaaacaaaa     7200

atgtctctag gtttagtcag agctttcaca agtaataacc tttctgtatt aaaatcagag     7260

taaccctttc tgtattgagt gcagtgtttt ttactctttt ctcatgcaca tgttacgttg     7320

gagaaaatgt ttacaaaaat ggttttgtta cactaatgcg caccacatat ttatggttta     7380

ttttaagtga ctttttatgg gttatttagg ttttcgtctt agttgtagca cacttaccct     7440

aattttgcca attattaatt tgctaaatag taatacaaat gacaaactgc attaaattta     7500

ctaattataa aagctgcaaa gcagactggt ggcaagtaca cagccctttt ttttgcagtg     7560

ctaacttgtc tactgtgtat tatgaaaatt actgttgtcc ccccaccctt ttttccttaa     7620

ataaagtaaa aatgacacct aaaaaaaaaa aaaaaaaa                             7658


<210>  2087
<211>  1785
<212>  DNA
<213>  homo sapiens

<400>  2087
gtctgacgtc acttccgtcg catttcgggg cggtaccaag atggactcct cgcgggcccg       60

gcagcagctc cggcggcgat tcctcctcct gccggacgcc gaggcccagc tggaccgcga      120

gggtgacgcc gggccgggtg aggcgcgcac caagccgccc cgaggttctc agaggcgagg      180

cgtcggaaaa cggccggcct ccggcagccc tggcccagtc tggaaggact gagtttcggc      240

tttgcaagtc gaatatttaa tgtcagggaa gatccttaga atcgcggagt gctgtgcatc      300

gtcatttcag ctgcgcttca gaattctctg gagagctgat ttgacaccta tttggaaata      360

gcgattaaaa ttaaaaatac ccaccagttt taagtcttaa ggatttacca gaaacatgcg      420

tgtaccgcag tgtacaatga tgtgcgcagt gtttcacttc aggattgctt gtaatagcga      480

attactggaa atatctgcct tgcccgtcag cagaaagctg tttaagtaaa tttgggtata      540

tgtatacctg acacatcagg tcgactcgta tgtaccaatg gggatgattt tcaaagggaa      600

gtgtggaaca ctatggtatg ccgccatttg ggtacaaaac agaaacctcc acagctgttg      660

agaaaaagga gaaacctctt ccaagactta atatccattc tggattctgg attttggcat      720

ccattgttgt gacctattat gttgacttct ttaaaaccct taaagaaaac ttccacacta      780

gcagctggtt tctctgtggc agtgccttgt tgcttgtcag tttatcaatt gcattttact      840

gcatagtcta cctggaatgg tattgtggaa ttggagaata tgatgtcaag tatccagcct      900

tgatacccat taccactgcc tcctttattg cagcaggaat ttgcttcaac attgctttat      960

ggcatgtgtg gtcgtttttc actccattgt tgttgtttac ccagtttatg ggggttgtca     1020

tgtttatcac actccttgga tgatttccga agagacaggg tcttctatgt tgcccaggct     1080

gtctttgaac tcctgggatc aagtgatcct cctgcctcag ccttcgaagt agttgggact     1140

acaggcccac gccaccgtgc ctggctggac atgtaaattt gaagtgaatg gttaaacatc     1200

cagctagctg aaagcatggc agaccctaac agaaaagcta cagtgtgttt ttgcagctat     1260

gaagtgaatg gtttcctggg gaaaattgtg actttgtata actgttgttg aaaccagaat     1320

aaattatatt tcacttgcat atgcataaat tattaaaatt ttcagaagtc agtgatacag     1380

aagtactatt ttgcaatgtt aatctgtttg agtctttgga gaaagtggtt tcattgtagg     1440

tacatagtgc actgttaata ttttaaacaa gtagttcact cttccattta agggatagca     1500

gttccttgta taaaatgact ggatgtgtat aaaggaatta tgttgtcatg tgcctttaac     1560

cagctttagt aattactata atctcatatt tatgatagtt ttgttaggtg acaggaccaa     1620

atgaaaatat tttatgtttt ctcatcactt tagattttat cattatgtac attactgggt     1680

ttttagcatt tcctaatgtg aagttttaat cacttttaag tatacatttt tttctgtatc     1740

atttaaataa aatattttta taactttaaa aaaaaaaaaa aaaaa                     1785


<210>  2088
<211>  2461
<212>  DNA
<213>  homo sapiens

<400>  2088
gtcagtaaca gttgattgtt acattcagta acactgaatg tcagtgcagt ccaatttaca       60

ggctggagca gcagctgcat cctgcatttc cccgaagtat tacatgattt tcactccttg      120

caaactttgc catctttgtt gcagagaatc ggaaatcaat atgcatagca aagtcacaat      180

catatgcatc agatttctct tttggtttct tttgctctgc atgcttattg ggaagtcaca      240

tactgaagat gacatcataa ttgcaacaaa gaatggaaaa gtcagaggga tgaacttgac      300

agtttttggt ggcacggtaa cagcctttct tggaattccc tatgcacagc cacctcttgg      360

tagacttcga ttcaaaaagc cacagtctct gaccaagtgg tctgatattt ggaatgccac      420

aaaatatgca aattcttgct gtcagaacat agatcaaagt tttccaggct tccatggatc      480

agagatgtgg aacccaaaca ctgacctcag tgaagactgt ttatatctaa atgtatggat      540

tccagcacct aaaccaaaaa atgccactgt attgatatgg atttatggtg gtggttttca      600

aactggaaca tcatctttac atgtttatga tggcaagttt ctggctcggg ttgaaagagt      660

tattgtagtg tcaatgaact atagggtggg tgccctagga ttcttagctt tgccaggaaa      720

tcctgaggct ccagggaaca tgggtttatt tgatcaacag ttggctcttc agtgggttca      780

aaaaaatata gcagcctttg gtggaaatcc taaaagtgta actctctttg gagaaagtgc      840

aggagcagct tcagttagcc tgcatttgct ttctcctgga agccattcat tgttcaccag      900

agccattctg caaagtggat cctttaatgc tccttgggcg gtaacatctc tttatgaagc      960

taggaacaga acgttgaact tagctaaatt gactggttgc tctagagaga atgagactga     1020

aataatcaag tgtcttagaa ataaagatcc ccaagaaatt cttctgaatg aagcatttgt     1080

tgtcccctat gggactcctt tgtcagtaaa ctttggtccg accgtggatg gtgattttct     1140

cactgacatg ccagacatat tacttgaact tggacaattt aaaaaaaccc agattttggt     1200

gggtgttaat aaagatgaag ggacagcttt tttagtctat ggtgctcctg gcttcagcaa     1260

agataacaat agtatcataa ctagaaaaga atttcaggaa ggtttaaaaa tattttttcc     1320

aggagtgagt gagtttggaa aggaatccat cctttttcat tacacagact gggtagatga     1380

tcagagacct gaaaactacc gtgaggcctt gggtgatgtt gttggggatt ataatttcat     1440

atgccctgcc ttggagttca ccaagaagtt ctcagaatgg ggaaataatg cctttttcta     1500

ctattttgaa caccgatcct ccaaacttcc gtggccagaa tggatgggag tgatgcatgg     1560

ctatgaaatt gaatttgtct ttggtttacc tctggaaaga agagataatt acacaaaagc     1620

cgaggaaatt ttgagtagat ccatagtgaa acggtgggca aattttgcaa aatatgggaa     1680

tccaaatgag actcagaaca atagcacaag ctggcctgtc ttcaaaagca ctgaacaaaa     1740

atatctaacc ttgaatacag agtcaacaag aataatgacg aaactacgtg ctcaacaatg     1800

tcgattctgg acatcatttt ttccaaaagt cttggaaatg acaggaaata ttgatgaagc     1860

agaatgggag tggaaagcag gattccatcg ctggaacaat tacatgatgg actggaaaaa     1920

tcaatttaac gattacacta gcaagaaaga aagttgtgtg ggtctctaat taatagattt     1980

accctttata gaacatattt tcctttagat caaggcaaaa atatcaggag cttttttaca     2040

cacctactaa aaaagttatt atgtagctga aacaaaaatg ccagaaggat aatattgatt     2100

cctcacatct ttaacttagt attttaccta gcatttcaaa acccaaatgg ctagaacgtg     2160

tttaattaaa tttcacaata taaagttcta cagttaatta tgtgcatatt aaaacaatgg     2220

cctggttcaa tttctttctt tccttaataa atttaagttt ttccccccaa aattatcagt     2280

gctctgcttt tagtcacgtg tattttcatt accactcgta aaaaggtatc ttttttaaat     2340

gaattaaata ttgaaacact gtacaccata gtttacaata ttatgtttcc taattaaaat     2400

aagaattgaa tgtcaatatg agatattaaa ataagcacag aaaatcaaaa aaaaaaaaaa     2460

a                                                                     2461


<210>  2089
<211>  4166
<212>  DNA
<213>  homo sapiens

<400>  2089
gtgcaaaata ttgtgcaagg cccgggtaca gaacaaggaa taataagaca cgccctgaag       60

gagtacatcg tctagtgagg gacagaccaa gcacgcaaaa caaattgcaa tataatgtga      120

taagttcttt aaaagaggta agagcaacgt gctttgggag cagagaagag ggagaaagca      180

gcatcttgcc tggatgagcc aggggacaca gaagagaagc ccactatctc atttaatctt      240

tacaactctc ttgcaaggtt ccctggttgt gaaaatacat gagataaatc atgaaggcca      300

ctatcatcct ccttctgctt gcacaagttt cctgggctgg accgtttcaa cagagaggct      360

tatttgactt tatgctagaa gatgaggctt ctgggatagg cccagaagtt cctgatgacc      420

gcgacttcga gccctcccta ggcccagtgt gccccttccg ctgtcaatgc catcttcgag      480

tggtccagtg ttctgatttg ggtctggaca aagtgccaaa ggatcttccc cctgacacaa      540

ctctgctaga cctgcaaaac aacaaaataa ccgaaatcaa agatggagac tttaagaacc      600

tgaagaacct tcacgcattg attcttgtca acaataaaat tagcaaagtt agtcctggag      660

catttacacc tttggtgaag ttggaacgac tttatctgtc caagaatcag ctgaaggaat      720

tgccagaaaa aatgcccaaa actcttcagg agctgcgtgc ccatgagaat gagatcacca      780

aagtgcgaaa agttactttc aatggactga accagatgat tgtcatagaa ctgggcacca      840

atccgctgaa gagctcagga attgaaaatg gggctttcca gggaatgaag aagctctcct      900

acatccgcat tgctgatacc aatatcacca gcattcctca aggtcttcct ccttccctta      960

cggaattaca tcttgatggc aacaaaatca gcagagttga tgcagctagc ctgaaaggac     1020

tgaataattt ggctaagttg ggattgagtt tcaacagcat ctctgctgtt gacaatggct     1080

ctctggccaa cacgcctcat ctgagggagc ttcacttgga caacaacaag cttaccagag     1140

tacctggtgg gctggcagag cataagtaca tccaggttgt ctaccttcat aacaacaata     1200

tctctgtagt tggatcaagt gacttctgcc cacctggaca caacaccaaa aaggcttctt     1260

attcgggtgt gagtcttttc agcaacccgg tccagtactg ggagatacag ccatccacct     1320

tcagatgtgt ctacgtgcgc tctgccattc aactcggaaa ctataagtaa ttctcaagaa     1380

agccctcatt tttataacct ggcaaaatct tgttaatgtc attgctaaaa aataaataaa     1440

agctagatac tggaaaccta actgcaatgt ggatgtttta cccacatgac ttattatgca     1500

taaagccaaa tttccagttt aagtaattgc ctacaataaa aagaaatttt gcctgccatt     1560

ttcagaatca tcttttgaag ctttctgttg atgttaactg agctactaga gatattctta     1620

tttcactaaa tgtaaaattt ggagtaaata tatatgtcaa tatttagtaa agcttttctt     1680

ttttaatttc caggaaaaaa taaaaagagt atgagtcttc tgtaattcat tgagcagtta     1740

gctcatttga gataaagtca aatgccaaac actagctctg tattaatccc catcattact     1800

ggtaaagcct catttgaatg tgtgaattca atacaggcta tgtaaaattt ttactaatgt     1860

cattattttg aaaaaataaa tttaaaaata cattcaaaat tactattgta tacaagctta     1920

attgttaata ttccctaaac acaattttat gaagggagaa gacattggtt tgttgacaat     1980

aacagtacat cttttcaagt tctcagctat ttcttctacc tctccctatc ttacatttga     2040

gtatggtaac ttatgtcatc tatgttgaat gtaagcttat aaagcacaaa gcatacattt     2100

cctgactggt ctagagaact gatgtttcaa tttacccctc tgctaaataa atattaaaac     2160

tatcatgtga cttcatgtaa tcaggctgaa catttctaca attactagat gtattagacg     2220

taagtatttt ctttagttaa accacccatg ttagaaatgt tttctgtaga atttataaac     2280

aactatcaat gcagacaatt taataagcct ggggatgatt tacttacagt aaacatttat     2340

caaattgtac atttgtgcta tcaacaatta ataagcaaat atgtgaaaat agtttctgtc     2400

ttctatgaag ttagatattt gatggttaaa acccctataa atcatagttt catatgggaa     2460

aaaataattg aaatacagtg taaatttaaa taatttatta agtatagcaa ataattgaaa     2520

tatggtggac taaattttgt catagaaata tgtgcaagtt atagtagtgg ctcacatgag     2580

aggtaatcaa ttctgctaat agtagcagaa tgagtgcagt ggaacatgaa aaacttgagg     2640

agataacagt tgaggtgggt ttccatagat gcataatagt tcaagagcaa gatttggtgg     2700

ggaggcacta ttcaagacag ggactaagtt caaaatccaa gacgtatgct gggacacacc     2760

tctgacaggt tggcataaag gaggcttaat caaactattt ttcttcttct gaaacagaag     2820

caataatttt catttacatt tgacatatcc cgaggtaata ttaacattag ggaaagttac     2880

tcttttccat ctttccacat tcttgcagga ccataaaatc tgaattttcc agtattttta     2940

ataagaggga agaaacctct ctttttcttc tctttttcat ctcccaagag atcctcctct     3000

catgactaca gttgaatagg tggtttctat tggaagacat tcaggaattc aaggtgcatg     3060

tccataaatg gacttttttt gttgttgttc agagctggac cttgaatgat gcatccttct     3120

ctctgttgta accatgaata atgcaccctt catgctatag cctttaacga ttcacccttc     3180

ttattgtaac cttgaatgat tcacccttta tggtgtagcc ttgagtgacg cacccttcat     3240

gttgtagcct tcaatgatgc acactccatg ttatagcctt gaatgatata ccctttatgc     3300

tgcagccttt ctcttatggg gaaaagcctg cagatatcct gctgcttaac tgacaagtgt     3360

ggtgagaaat aagtagaaat ctaaagaggg gaagaccatt ttggacactt atctgcaagg     3420

cagatccaac acacttttcc agtagtcaag ctacttctaa ttttgttcag tatcaaaatg     3480

agaaacaggc ctgattctcc agcactcttg tcaacacaac ttccccccat atttatatat     3540

atacacacac atatatatct ttatatatat acacacatat atatctttat atatatatat     3600

ttatatatat atctttttgc atatatacat atatatgtat ctttatttcc tttgaaataa     3660

agataaatat agctgatttc tttggcttcg acacttacta tttgcatgac taagggaagc     3720

tagttaacct ttctgtgact catttccttg tccataaaat gggaatatta attgtacatg     3780

tcttatggat tggtgtgtga attcagttag cgagtgtaga atataactta tagatcaaag     3840

tagagtaaat ggaaagggct caactatggt gttgctactg ccattgttat tacaggcaca     3900

cagttcgagc tataatcatt tcaagggaaa ttcttatgtg tcagttctgg atcgaggtct     3960

gagattctgc atttcaaaca aacttccagg aatgctgctg cttcttggtc cacacttgga     4020

gaaataagtc agcagagagt cctctcgttt cctattgtac catgtctgtc ttttgtctcc     4080

tgcttattgg cctctgtaag gaactcacag ctgctataat aaagtaccaa aaactgggtg     4140

gcttaaaaca aaaaaaaaaa aaaaaa                                          4166


<210>  2090
<211>  3643
<212>  DNA
<213>  homo sapiens

<400>  2090
taagaaacga cacacagatt aggcagtgct actcttctta aatctctcat ttgtttccta       60

ggttccctgg ttgtgaaaat acatgagata aatcatgaag gccactatca tcctccttct      120

gcttgcacaa gtttcctggg ctggaccgtt tcaacagaga ggcttatttg actttatgct      180

agaagatgag gcttctggga taggcccaga agttcctgat gaccgcgact tcgagccctc      240

cctaggccca gtgtgcccct tccgctgtca atgccatctt cgagtggtcc agtgttctga      300

tttggaactg ggcaccaatc cgctgaagag ctcaggaatt gaaaatgggg ctttccaggg      360

aatgaagaag ctctcctaca tccgcattgc tgataccaat atcaccagca ttcctcaagg      420

tcttcctcct tcccttacgg aattacatct tgatggcaac aaaatcagca gagttgatgc      480

agctagcctg aaaggactga ataatttggc taagttggga ttgagtttca acagcatctc      540

tgctgttgac aatggctctc tggccaacac gcctcatctg agggagcttc acttggacaa      600

caacaagctt accagagtac ctggtgggct ggcagagcat aagtacatcc aggttgtcta      660

ccttcataac aacaatatct ctgtagttgg atcaagtgac ttctgcccac ctggacacaa      720

caccaaaaag gcttcttatt cgggtgtgag tcttttcagc aacccggtcc agtactggga      780

gatacagcca tccaccttca gatgtgtcta cgtgcgctct gccattcaac tcggaaacta      840

taagtaattc tcaagaaagc cctcattttt ataacctggc aaaatcttgt taatgtcatt      900

gctaaaaaat aaataaaagc tagatactgg aaacctaact gcaatgtgga tgttttaccc      960

acatgactta ttatgcataa agccaaattt ccagtttaag taattgccta caataaaaag     1020

aaattttgcc tgccattttc agaatcatct tttgaagctt tctgttgatg ttaactgagc     1080

tactagagat attcttattt cactaaatgt aaaatttgga gtaaatatat atgtcaatat     1140

ttagtaaagc ttttcttttt taatttccag gaaaaaataa aaagagtatg agtcttctgt     1200

aattcattga gcagttagct catttgagat aaagtcaaat gccaaacact agctctgtat     1260

taatccccat cattactggt aaagcctcat ttgaatgtgt gaattcaata caggctatgt     1320

aaaattttta ctaatgtcat tattttgaaa aaataaattt aaaaatacat tcaaaattac     1380

tattgtatac aagcttaatt gttaatattc cctaaacaca attttatgaa gggagaagac     1440

attggtttgt tgacaataac agtacatctt ttcaagttct cagctatttc ttctacctct     1500

ccctatctta catttgagta tggtaactta tgtcatctat gttgaatgta agcttataaa     1560

gcacaaagca tacatttcct gactggtcta gagaactgat gtttcaattt acccctctgc     1620

taaataaata ttaaaactat catgtgactt catgtaatca ggctgaacat ttctacaatt     1680

actagatgta ttagacgtaa gtattttctt tagttaaacc acccatgtta gaaatgtttt     1740

ctgtagaatt tataaacaac tatcaatgca gacaatttaa taagcctggg gatgatttac     1800

ttacagtaaa catttatcaa attgtacatt tgtgctatca acaattaata agcaaatatg     1860

tgaaaatagt ttctgtcttc tatgaagtta gatatttgat ggttaaaacc cctataaatc     1920

atagtttcat atgggaaaaa ataattgaaa tacagtgtaa atttaaataa tttattaagt     1980

atagcaaata attgaaatat ggtggactaa attttgtcat agaaatatgt gcaagttata     2040

gtagtggctc acatgagagg taatcaattc tgctaatagt agcagaatga gtgcagtgga     2100

acatgaaaaa cttgaggaga taacagttga ggtgggtttc catagatgca taatagttca     2160

agagcaagat ttggtgggga ggcactattc aagacaggga ctaagttcaa aatccaagac     2220

gtatgctggg acacacctct gacaggttgg cataaaggag gcttaatcaa actatttttc     2280

ttcttctgaa acagaagcaa taattttcat ttacatttga catatcccga ggtaatatta     2340

acattaggga aagttactct tttccatctt tccacattct tgcaggacca taaaatctga     2400

attttccagt atttttaata agagggaaga aacctctctt tttcttctct ttttcatctc     2460

ccaagagatc ctcctctcat gactacagtt gaataggtgg tttctattgg aagacattca     2520

ggaattcaag gtgcatgtcc ataaatggac tttttttgtt gttgttcaga gctggacctt     2580

gaatgatgca tccttctctc tgttgtaacc atgaataatg cacccttcat gctatagcct     2640

ttaacgattc acccttctta ttgtaacctt gaatgattca ccctttatgg tgtagccttg     2700

agtgacgcac ccttcatgtt gtagccttca atgatgcaca ctccatgtta tagccttgaa     2760

tgatataccc tttatgctgc agcctttctc ttatggggaa aagcctgcag atatcctgct     2820

gcttaactga caagtgtggt gagaaataag tagaaatcta aagaggggaa gaccattttg     2880

gacacttatc tgcaaggcag atccaacaca cttttccagt agtcaagcta cttctaattt     2940

tgttcagtat caaaatgaga aacaggcctg attctccagc actcttgtca acacaacttc     3000

cccccatatt tatatatata cacacacata tatatcttta tatatataca cacatatata     3060

tctttatata tatatattta tatatatatc tttttgcata tatacatata tatgtatctt     3120

tatttccttt gaaataaaga taaatatagc tgatttcttt ggcttcgaca cttactattt     3180

gcatgactaa gggaagctag ttaacctttc tgtgactcat ttccttgtcc ataaaatggg     3240

aatattaatt gtacatgtct tatggattgg tgtgtgaatt cagttagcga gtgtagaata     3300

taacttatag atcaaagtag agtaaatgga aagggctcaa ctatggtgtt gctactgcca     3360

ttgttattac aggcacacag ttcgagctat aatcatttca agggaaattc ttatgtgtca     3420

gttctggatc gaggtctgag attctgcatt tcaaacaaac ttccaggaat gctgctgctt     3480

cttggtccac acttggagaa ataagtcagc agagagtcct ctcgtttcct attgtaccat     3540

gtctgtcttt tgtctcctgc ttattggcct ctgtaaggaa ctcacagctg ctataataaa     3600

gtaccaaaaa ctgggtggct taaaacaaaa aaaaaaaaaa aaa                       3643


<210>  2091
<211>  4054
<212>  DNA
<213>  homo sapiens

<400>  2091
agagctatga cctgatttgt gacgcaccct cagaactgca gtaatggtcc agctgcttca       60

caggcaactg gtaaccacct catttgggga tgtttctgcc ttgctagcag tgccagagag      120

aacttcatca ttgtcacctc atcaaagact actttttcag acatctcctg tagggctaga      180

ttcagagagc agcttctgat atttggaggg tgatctttag acagtgactg agtatggatc      240

atttgaacga ggcaactcag gggaaagaac attcagaaat gtctaacaat gtgagtgatc      300

cgaagggtcc accagccaag attgcccgcc tggagcagaa cgggagcccg ctaggaagag      360

gaaggcttgg gagtacaggt gcaaaaatgc agggagtgcc tttaaaacac tcgggccatc      420

tgatgaaaac caaccttagg aaaggaacca tgctgccagt tttctgtgtg gtggaacatt      480

atgaaaacgc cattgaatat gattgcaagg aggagcatgc agaatttgtg ctggtgagaa      540

aggatatgct tttcaaccag ctgatcgaaa tggcattgct gtctctaggt tattcacata      600

gctctgctgc ccaggccaaa gggctaatcc aggttggaaa gtggaatcca gttccactgt      660

cttacgtgac agatgcccct gatgctacag tagcagatat gcttcaagat gtgtatcatg      720

tggtcacatt gaaaattcag ttacacagtt gccccaaact agaagacttg cctcccgaac      780

aatggtcgca caccacagtg aggaatgctc tgaaggactt actgaaagat atgaatcaga      840

gttcattggc caaggagtgc cccctttcac agagtatgat ttcttccatt gtgaacagta      900

cttactatgc aaatgtctca gcagcaaaat gtcaagaatt tggaaggtgg tacaaacatt      960

tcaagaagac aaaagatatg atggttgaaa tggatagtct ttctgagcta tcccagcaag     1020

gcgccaatca tgtcaatttt ggccagcaac cagttccagg gaacacagcc gagcagcctc     1080

catcccctgc gcagctctcc catggcagcc agccctctgt ccggacacct cttccaaacc     1140

tgcaccctgg gctcgtatca acacctatca gtcctcaatt ggtcaaccag cagctggtga     1200

tggctcagct gctgaaccag cagtatgcag tgaatagact tttagcccag cagtccttaa     1260

accaacaata cttgaaccac cctccccctg tcagtagatc tatgaataag cctttggagc     1320

aacaggtttc gaccaacaca gaggtgtctt ccgaaatcta ccagtgggta cgcgatgaac     1380

tgaaacgagc aggaatctcc caggcggtat ttgcacgtgt ggcttttaac agaactcagg     1440

gcttgctttc agaaatcctc cgaaaggaag aggaccccaa gactgcatcc cagtctttgc     1500

tggtaaacct tcgggctatg cagaatttct tgcagttacc ggaagctgaa agagaccgaa     1560

tataccagga cgaaagggaa aggagcttga atgctgcctc ggccatgggt cctgcccccc     1620

tcatcagcac accacccagc cgtcctcccc aggtgaaaac agctactatt gccactgaaa     1680

ggaatgggaa accagagaac aataccatga acattaatgc ttccatttat gatgagattc     1740

agcaggaaat gaagcgtgct aaagtgtctc aagcactgtt tgcaaaggtt gcagcaacca     1800

aaagccaggg atggttgtgc gagctgttac gctggaaaga agatccttct ccagaaaaca     1860

gaaccctgtg ggagaacctc tccatgatcc gaaggttcct cagtcttcct cagccagaac     1920

gtgatgccat ttatgaacag gagagcaacg cggtgcatca ccatggcgac aggccgcccc     1980

acattatcca tgttccagca gagcagattc agcaacagca gcagcaacag caacagcagc     2040

agcagcagca gcaggcaccg ccgcctccac agccacagca gcagccacag acaggccctc     2100

ggctcccccc acggcaaccc acggtggcct ctccagcaga gtcagatgag gaaaaccgac     2160

agaagacccg gccacgaaca aaaatttcag tggaagcctt gggaatcctc cagagtttca     2220

tacaagacgt gggcctgtac cctgacgaag aggccatcca gactctgtct gcccagctcg     2280

accttcccaa gtacaccatc atcaagttct ttcagaacca gcggtactat ctcaagcacc     2340

acggcaaact gaaggacaat tccggtttag aggtcgatgt ggcagaatat aaagaagagg     2400

agctgctgaa ggatttggaa gagagtgtcc aagataaaaa tactaacacc cttttttcag     2460

tgaaactaga agaagagctg tcagtggaag gaaacacaga cattaatact gatttgaaag     2520

actgagataa aagtatttgt ttcgttcaac agtgccactg gtatttacta acaaaatgaa     2580

aagtccacct tgtcttctct cagaaaacct ttgttgttca ttgtttggcc aatgaatctt     2640

caaaaacttg cacaaacaga aaagttggaa aaggataata cagactgcac taaatgtttt     2700

cctctgtttt acaaactgct tggcagcccc aggtgaagca tcaaggattg tttggtatta     2760

aaatttgtgt tcacgggatg caccaaagtg tgtaccccgt aagcatgaaa ccagtgtttt     2820

ttgttttttt tttagttctt attccggagc ctcaaacaag cattatacct tctgtgatta     2880

tgatttcctc tcctataatt atttctgtag cactccacac tgatctttgg aaacttgccc     2940

cttatttaaa aaaaaaaaag aaaaaaaaga gtttgttact ctattgtatg ttacaaaaga     3000

actatagact gtggaatgca gtttaaagat gacatatgcc aacaaatgcc ttgtattata     3060

tggcactgcc gtaattcaaa tttgttttta ttttggaaat aaaagttcac tgtacttttt     3120

tttcattctc attgttacat gattttttaa aaaaaggaaa agaaaatgtg aaacacaatt     3180

tagtcctcat tatttatttg tagatcctgc agcatcatgt tgtaattaat tttttggaag     3240

tttccgttaa atgtaatatt gcttctcttg ttaccatact gattcttttc tatttataaa     3300

tgtattttga tgggcagtaa aacaaagtgt cttaaaagtt ttaaatagag aaaatgtgct     3360

ttacacagtt gcctataaaa agtgctctat gttatccaag caattcatac tataagcttc     3420

actcttattg ttgtatgcaa tttttactat catgcaaata agcttaggta aataaaacta     3480

atagatcacc ttagaaaatt atgcaattaa tgtgaaaata attgatgttt gcaatgtgtc     3540

ttcctttggt ttacaatcaa ttttaaagct acatctgtat aaaatttctg tataaaggtg     3600

tatttctttt ttatgagttt atggctatga aaacagctat tttgttacag ctggctgttt     3660

ttataagtgt atcacaattt tctttatgca gaaatgttct gactaggagt ggttattgac     3720

tgtaactaca caattaaaat tgtttgtatc gtatgacatg gtagggtttg tctgcttatg     3780

tgaagtaact aaaggagtca aaggatggcc ctctcattta ggtgcatgtt aataacttgt     3840

tatttcactg attttaaaaa gagcaattga caagttactt gaaacactgt aaatttaaat     3900

cacaaacaca tgctcatttt taaataggta tgaaatttca caatgaaaat aacctgtttg     3960

gttaacattt tgcttaataa gtagagatag gatggtcaaa agactctccg acaaaaacaa     4020

atccagtctc tagcagttat gttgttagaa tgga                                 4054


<210>  2092
<211>  3021
<212>  DNA
<213>  homo sapiens

<400>  2092
gggcctactc tgccgccgcc gccgcccgcc cgctccagcc gccgccgccg ccgccaccgc       60

cctccaggct ccgggacccg gcccgcgcca ccgcccccgt gcgcgccccg ccgccgccgc      120

cttcgccttc gccttttgtt tcctccgctc cggcgccccc gccccggctc gcgctttgca      180

ggggacgcag cgcgcgcccc cagcgggccc gggaaaagcc gcggcgcgcg cgcgcgcctg      240

cgcggcggac ccctccttct cctccccgcg tgcgcgtgcc cttcttggct gcgcgccggc      300

gccgcctggc gggcgggagg ggaggtggca ggcgcgtttg caggaggggc gcacctcttc      360

gctcgcgcac ccccccggaa ggtagaccgg gaaggggagg cgggcgggcg gagaggagag      420

agtggcgcgc agtccagcga gggcgggggt tggctatgtg gggggtggtg caccccgcag      480

tctagacagt ctgatccggg ctgggggcgt gtacactcgg cgcacctgcg agactacaga      540

gcctcgggcc ggcacgtgtg gggagtgtgg acacgtctgc tgcgccccgc ttctcgctgc      600

tgaggggaag ggagggggcg ggcaggtgca gcggccgggc tagtgggagg gggcggcggc      660

catggagcgg gtgaacgacg cttcgtgcgg cccgtctggc tgctacacat accaggtgag      720

cagacacagc acggagatgc tgcacaacct gaaccagcag cgcaaaaacg gcgggcgctt      780

ctgcgacgtg ctcttgcggg taggcgacga gagcttccca gcgcaccgcg ccgtgctggc      840

cgcctgcagc gagtactttg agtcggtgtt cagcgcccag ttgggcgacg gcggagctgc      900

ggacgggggt ccggctgatg tagggggcgc gacggcagca ccaggcggcg gggccggggg      960

cagccgggag ctggagatgc acactatcag ctccaaggta tttggggaca ttctggactt     1020

cgcctacact tcccgcatcg tggtgcgctt ggagagcttt cccgaactca tgacggccgc     1080

caagttcctg ctgatgaggt cggttatcga gatctgccag gaagtcatca aacagtccaa     1140

cgtacagatc ctggtacccc ctgcccgcgc cgatataatg ctctttcgcc cccctgggac     1200

ctcggacttg ggcttccctt tggacatgac caacggggca gccttggcag ccaacagcaa     1260

tggcatcgcc ggcagcatgc agccagagga ggaggcagct cgggcggctg gtgcagccat     1320

tgcaggccaa gcctctttgc ctgtgttacc tggggtggac cgcttgccca tggtggctgg     1380

acccctatcc ccccaactgc tgacttcccc attccccagt gtggcatcca gtgcccctcc     1440

cctgactggc aagcgaggcc ggggccgccc aaggaaggcc aacctgctgg actcaatgtt     1500

tgggtcccca gggggcctga gggaggcagg catccttcca tgcggtctat gtggtaaggt     1560

gttcactgat gccaaccggc tccggcagca cgaggcccag cacggtgtca ccagcctcca     1620

gctgggctac atcgaccttc ctcctccgag gctgggtgag aatgggctac ccatctctga     1680

agaccccgac ggcccccgaa agaggagccg gaccaggaag caggtggctt gtgagatctg     1740

cggcaagatc ttccgtgatg tgtatcatct taaccggcac aagctgtccc actctgggga     1800

gaagccctac tcctgccctg tgtgtgggtt gcggttcaag agaaaagacc gcatgtccta     1860

ccatgtgcgg tcccatgatg ggtccgtggg caagccttac atctgccaga gctgtgggaa     1920

aggcttctcc aggcctgatc acttgaacgg acatatcaag caggtgcaca cttctgagcg     1980

gcctcacaag tgtcaggtgt gggttgggag cagcagcggc ctgccgcccc tggaacctct     2040

tcctagcgac ctgccatcat gggactttgc ccagcctgct ttgtggaggt cgtcccattc     2100

ggttcctgac accgcctttt ccctttctct aaaaaaatca ttcccagccc ttgaaaacct     2160

gggcccagca cactccagca acactctctt ctgcccagcc ccgccgggat atctgaggca     2220

gggctggacc accccagagg gcagcagggc ctttacccag tggcctgttg gctagcctgg     2280

gcctccctgg agagggttga cagtggaagg gaacaggagg ggcatttggc ctgagacccc     2340

tgcttttggg agaggctagc agggtggttc ctgcccagca tgcccagctc ctccctgggt     2400

gactcggagt ctttcccatg tcagagcccc caaatggggg tagcaaggag cacctttctg     2460

gaacccccta tagcatccaa gtttctttct gggctctctt gccttttccc ccctttcaca     2520

gatggcaccc ctgggcatct gtccttgcct aggtgatttt ggaggttggt gccttcctgg     2580

gaactagcca ccagcttatc tgcttccctt cccctggcat cacttcccat aggcctgggg     2640

tttctagact ggggcctggc cacccctttc cccactccac gagtgagtcg gcctccagag     2700

aagactggca caattccaac tagagtcaac ccatgctgcc ctctgccctt cccactcaga     2760

tctagatcct gctttcattt ctggctagtg aagtagactt ttgtgttttt gaggtttatt     2820

agcaggtctg ctcaggaacc aaactaatga gtagctttat attgggccac cccaatatat     2880

ggctttgggg gctgaaaaag cagatgtaga ccccctccct cggatcctta ttggtgtgcc     2940

ctttagcact ccgcagactc tgcggggtga acaggagtga tgataaaatt tttcattcta     3000

aaaaaaaaaa aaaaaaaaaa a                                               3021


<210>  2093
<211>  4012
<212>  DNA
<213>  homo sapiens

<400>  2093
gtgggagccc gcgaggtggc ccgagcgagg gccccgcatc cccgcagagc ccgcccgagg       60

gcgcagcctg ccacgccagg ggaggcggcc gggcggcggg gaacggcggg ggcggagcgc      120

agcctcccga cgccgccgcc tcaccgcccc cctccgcctc ctcggcctcc gctcgcagcc      180

gccgcctccg cctccgccgg gctgaggagc cgggagtccg ccgcgccggc tcggggctgc      240

gggatgggga gttagcgcca cggcggcggc agtggccgca gcgcaccccg ccgccgccca      300

ggagcccgtc cagccagggg tgccgggccc gcccagcccg ccccggagcc aggcccgcgg      360

gcggcggcgg agctgggcag gtggatgcgg ctggaagatg gcgccctcgg gcccgggcag      420

cagcgccagg cggcggtgcc ggcgggtgct gtactggatc ccggtggtgt tcatcaccct      480

cctgctcggc tggtcctact acgcctacgc catccagctg tgcatagtgt ccatggaaaa      540

cactggcgaa caagttgtgt gcctgatggc ctatcatcta ctttttgcaa tgtttgtctg      600

gtcatactgg aaaactatct ttacattacc aatgaatcct tcaaaagaat tccatctctc      660

ttatgcagag aaagatttgt tggagagaga gccaagagga gaagcccatc aggaagttct      720

taggcgagca gccaaggatc ttcccatcta taccaggacc atgtctggag ccatccgata      780

ctgtgacaga tgccaactta taaaaccaga tcgctgccat cactgctccg tctgtgataa      840

atgtattttg aagatggatc atcattgtcc atgggtgaac aattgtgttg gattttcaaa      900

ttataagttc tttctccttt tcttggctta ttctctgctc tactgccttt ttattgcggc      960

aacagattta cagtatttta tcaaattttg gacaaatggc ctacctgata ctcaagccaa     1020

gttccatatt atgtttttat tctttgctgc agctatgttt tctgtcagct tgtcttctct     1080

gtttggctat cattgttggc tagtcagcaa aaataaatct acattagagg cattcagaag     1140

tccagtattt cgacatggaa cagataagaa tggattcagc ttgggtttca gtaaaaacat     1200

gcgacaagtt tttggtgatg agaagaagta ctggttgcta cccatttttt caagtctagg     1260

tgatggctgc tcctttccaa cttgccttgt taaccaggat cctgaacaag catctactcc     1320

tgcagggctg aattccacag ctaaaaatct cgaaaaccat cagtttcctg caaagccatt     1380

gagagagtcc cagagccacc ttcttactga ttctcagtct tggacggaga gcagcataaa     1440

cccaggaaaa tgcaaagctg gtatgagcaa tcctgcatta accatggaaa atgagactta     1500

actcttcaag caagataaat tcatacttta taaaagtatc aatgctgtag atggatggaa     1560

gaggcttccc acaggaaggt gccaccagtc agttgtgcct atgtcccttt ggctggaaat     1620

gcagaatatg aattgattag ttctctccaa gccattgctt aaaatataac atgttttgga     1680

tccaatacac acattgttac aactaacaca aattcctatt aaatattaaa agtagttctg     1740

gtttattaat caacggggaa aacatcttct ccaaaaaact tggaataaat ccaaggacca     1800

gtttttaccc aaatatatgg gtagcacagt ttatcacata gaaactccat taatcatctg     1860

attttccgaa tctgaaaatt gagactatta agatattagg atttcagaga tttcaagtca     1920

cattataatg ataagcatta ttcataaaac ttgttacctt taagaaggtg gaagtggcaa     1980

accatacttc ttttttttcc tctgatgtga atccagcctc agactgagtg aactgtaata     2040

attatgaatt cattacagag tccaggtggc ctgcagttga agatcatcaa ccatttttgc     2100

ctcacttaat tccagccttt tgttttctgc tggaaaataa gtgtggacat tgaagcttga     2160

gctctcaaag cagttggctg gaatactttt gtcagaatac ggtacatttc tattacatca     2220

gaaatatatt ttcatctctt cttgttaaat tgggaggaaa tttatgatag caattatgaa     2280

gattgtttta tgacattctt ttgtcagttt ggctttctaa aaatctcttt ttagattatt     2340

tctcctgttg aacatagtaa aactattgaa tttctcttaa gaattcctaa taggtcaata     2400

gatttaccct ccagtgatat ctatattatt tctttctcgt ctcatcaaaa tgatgacagg     2460

taaactatat ttttccttaa acacctatta cagttaaatt atgcaaatca ttaaataaaa     2520

atcatacaac ttttggaaag ttagttcaac atgaactaaa atggcatgct atttggaaat     2580

ttagtttgag ataaactaaa gtgtgttgat gccagaatgt tcagcttcag taaatataat     2640

aagctcttgt gccttgtatg cactatttaa aaaaagtttt ttttatttga gtccagtata     2700

attcatgtaa atgttaacaa ttagaataat actctgtatg cttttttgat actgattttg     2760

agaatttaaa gcagattacc ttttaaaact ggaccaacta agtaattggt atttaatcaa     2820

agagaaaatg gtaataaact tttcaaaatc tttgttaaac caaacattca acacaaaata     2880

aactagaagg ccagaggata atggaataaa agatcattgc aattacttat ccttcctaaa     2940

aatatagttt tatattaatt gtgcttatgg aagaaacaat gtcagccaag tccattttat     3000

agtttgagtg caattctttg aacaatagaa atatctgcag tctttcacag atttgtatta     3060

tgctgaagag tttcatctga caatctgctt caagaaatct cagaaaatat gataacattt     3120

taactttcat tttagagcac gttttggtca tttttaaaaa tacctaaagt gccagaccgg     3180

aacctatagc tactgctaga agtcttaaaa aaaccaacag cagcacagga tgtattaaga     3240

attatatgaa gtcaggtttg tttttttttt tttttttttt tcaaagcaca gtactgttag     3300

ctgtttttgt ggacaggatt cgattaagta ttccctcttg tcaaactgga agctagggga     3360

aaaagaggga tttttatcct ttactcttct agagtactgt taatgcccct ttcccacagt     3420

cttttatata attaaatata tgtcaataca cattagaatc agatttgaaa aagttaaaac     3480

aatttcattg ttgtaattgt tccctttctg ttttcatata gtgaataacc tttaaagggt     3540

tgttttgttt tgttttgaat tataggagtt ataatctttg gagatgattg catatctcat     3600

tagatatgca atataaattt atctgagtga acaaagtgct aaataaatag atctacattt     3660

tgtacatatt tatataaaat ttacctttaa gtatttactt taaaaaattt aatggcttaa     3720

ctcgaacttg aagacacata cttcaactgt ccttattgtc cattaaactg ataattttga     3780

tttttcttgc ttttatagat tttactatat aggaatcaag atttaagaaa ttttgcatta     3840

aaaatagtgt accaatgctt catatacgtt agttatttgc tattatgtag ggaagaggat     3900

tgttatttca aagatatatt aaagaacagt tgcatctgaa tataatcatg atgcattcaa     3960

tgaagttcat atccatgaat tcactcctaa tataccctaa taaagtggtt ga             4012


<210>  2094
<211>  2697
<212>  DNA
<213>  homo sapiens

<400>  2094
acttgtccgt cacgtgcggc cgcccggcct ctcggccttg ccgcgcgcct ggcggggttg       60

ggggggcggg gaccaagatc tgctgcgcct gcgttgtggg cgttctcggg gagctgctgc      120

cgtagctgcc gccgccgcta ccaccgcgtt cgggtgtaga atttggaatc cctgcgccgc      180

gttaacaatg aagcagagtt cgaacgtgcc ggctttcctc agcaagctgt ggacgcttgt      240

ggaggaaacc cacactaacg agttcatcac ctggagccag aatggccaaa gttttctggt      300

cttggatgag caacgatttg caaaagaaat tcttcccaaa tatttcaagc acaataatat      360

ggcaagcttt gtgaggcaac tgaatatgta tggtttccgt aaagtagtac atatcgactc      420

tggaattgta aagcaagaaa gagatggtcc tgtagaattt cagcatcctt acttcaaaca      480

aggacaggat gacttgttgg agaacattaa aaggaaggtt tcatcttcaa aaccagaaga      540

aaataaaatt cgtcaggaag atttaacaaa aattataagt agtgctcaga aggttcagat      600

aaaacaggaa actattgagt ccaggctttc tgaattaaaa agtgagaatg agtccctttg      660

gaaggaggtg tcagaattac gagcaaagca tgcacaacag caacaagtta ttcgaaagat      720

tgtccagttt attgttacat tggttcaaaa taaccaactt gtgagtttaa aacgtaaaag      780

gcctctactt ctaaacacta atggagccca aaagaagaac ctgtttcagc acatagtcaa      840

agaaccaact gataatcatc atcataaagt tccacacagt aggactgaag gtttaaagcc      900

aagggagagg atttcagatg acatcattat ttatgatgtt actgatgata atgcagatga      960

agaaaatatc ccagttattc cagaaactaa tgaggatgtt atatctgatc cctccaactg     1020

tagccagtac cctgatattg tcatcgttga agatgacaat gaagatgagt atgcacctgt     1080

cattcagagt ggagagcaga atgaaccagc cagagaatcc ctaagttcag gcagtgatgg     1140

cagcagccct ctcatgtcta gtgctgtcca gctaaatggc tcatccagtc tgacctcaga     1200

agatccagtg accatgatgg attccatttt gaatgataac atcaatcttt tgggaaaggt     1260

tgagctgttg gattatcttg acagtattga ctgcagttta gaggacttcc aggccatgct     1320

atcaggaaga caatttagca tagacccaga tctcctggtt gatcttttca ctagttctgt     1380

gcagatgaat cccacagatt acatcaataa tacaaaatct gagaataaag gattagaaac     1440

taccaagaac aatgtagttc agccagtttc ggaagaggga agaaaatcta aatccaaacc     1500

agataagcag cttatccagt ataccgcctt tccacttctt gcattcctcg atgggaaccc     1560

tgcttcttct gttgaacagg cgagtacaac agcatcatca gaagttttgt cctctgtaga     1620

taaacccata gaagttgatg agcttctgga tagcagccta gacccagaac caacccaaag     1680

taagcttgtt cgcctggagc cattgactga agctgaagct agtgaagcta cactgtttta     1740

tttatgtgaa cttgctcctg cacctctgga tagtgatatg ccacttttag atagctaaat     1800

ccccaggaag tggactttac atgtatatat tcatcaaaat gatgaactat ttattttaaa     1860

gtatcatttg gtactttttt tgtaaattgc tttgttttgt ttaatcagat actgtggaat     1920

aaaagcacct tttgcttttc tcactaacca cacactcttg cagagctttc aggtgttact     1980

cagctgcata gttacgcaga tgtaatgcac attattggcg tatctttaag ttggattcaa     2040

atggccattt ttctccaatt ttggtaaatt ggatatcttt tttttacaaa tacgaccatt     2100

aacctcagtt aaatttttgt ttgttttcct gtttgatgct gtctatttgc attgagtgta     2160

agtcatttga actaatggta taactcctaa agctttctct gctccagtta tttttattaa     2220

atatttttca cttggcttat ttttaaaact gggaacataa agtgcctgta tcttgtaaaa     2280

cttcatttgt ttcttttggt tcagagaagt tcatttatgt tcaaagacgt ttattcatgt     2340

tcaacaggaa agacaaagtg tacgtgaatg ctcgctgtct gatagggttc cagctccata     2400

tatatagaaa gatcgggggt gggatgggat ggagtgagcc ccatccagtt agttggacta     2460

gttttaaata aaggttttcc ggtttgtgtt tttttgaacc atactgttta gtaaaataaa     2520

tacaatgaat gttgagtact agtgtctgtt atgtgtcttc tttagaggtg acactcacat     2580

gaaacaattt tttcttctca taggaagcag tagctttaaa ctgtctgtgg ttcattattc     2640

tcaatatgaa tcataccaag atatttgtgc ctcatctcga aaatatattg tatattg        2697


<210>  2095
<211>  4953
<212>  DNA
<213>  homo sapiens

<400>  2095
ggtttccgga gctgcggcgg cgcagactgg gagggggagc cgggggttcc gacgtcgcag       60

ccgagggaac aagccccaac cggatcctgg acaggcaccc cggcttggcg ctgtctctcc      120

ccctcggctc ggagaggccc ttcggcctga gggagcctcg ccgcccgtcc ccggcacacg      180

cgcagccccg gcctctcggc ctctgccgga gaaacaggat ggcccaatgg aatcagctac      240

agcagcttga cacacggtac ctggagcagc tccatcagct ctacagtgac agcttcccaa      300

tggagctgcg gcagtttctg gccccttgga ttgagagtca agattgggca tatgcggcca      360

gcaaagaatc acatgccact ttggtgtttc ataatctcct gggagagatt gaccagcagt      420

atagccgctt cctgcaagag tcgaatgttc tctatcagca caatctacga agaatcaagc      480

agtttcttca gagcaggtat cttgagaagc caatggagat tgcccggatt gtggcccggt      540

gcctgtggga agaatcacgc cttctacaga ctgcagccac tgcggcccag caagggggcc      600

aggccaacca ccccacagca gccgtggtga cggagaagca gcagatgctg gagcagcacc      660

ttcaggatgt ccggaagaga gtgcaggatc tagaacagaa aatgaaagtg gtagagaatc      720

tccaggatga ctttgatttc aactataaaa ccctcaagag tcaaggagac atgcaagatc      780

tgaatggaaa caaccagtca gtgaccaggc agaagatgca gcagctggaa cagatgctca      840

ctgcgctgga ccagatgcgg agaagcatcg tgagtgagct ggcggggctt ttgtcagcga      900

tggagtacgt gcagaaaact ctcacggacg aggagctggc tgactggaag aggcggcaac      960

agattgcctg cattggaggc ccgcccaaca tctgcctaga tcggctagaa aactggataa     1020

cgtcattagc agaatctcaa cttcagaccc gtcaacaaat taagaaactg gaggagttgc     1080

agcaaaaagt ttcctacaaa ggggacccca ttgtacagca ccggccgatg ctggaggaga     1140

gaatcgtgga gctgtttaga aacttaatga aaagtgcctt tgtggtggag cggcagccct     1200

gcatgcccat gcatcctgac cggcccctcg tcatcaagac cggcgtccag ttcactacta     1260

aagtcaggtt gctggtcaaa ttccctgagt tgaattatca gcttaaaatt aaagtgtgca     1320

ttgacaaaga ctctggggac gttgcagctc tcagaggatc ccggaaattt aacattctgg     1380

gcacaaacac aaaagtgatg aacatggaag aatccaacaa cggcagcctc tctgcagaat     1440

tcaaacactt gaccctgagg gagcagagat gtgggaatgg gggccgagcc aattgtgatg     1500

cttccctgat tgtgactgag gagctgcacc tgatcacctt tgagaccgag gtgtatcacc     1560

aaggcctcaa gattgaccta gagacccact ccttgccagt tgtggtgatc tccaacatct     1620

gtcagatgcc aaatgcctgg gcgtccatcc tgtggtacaa catgctgacc aacaatccca     1680

agaatgtaaa cttttttacc aagcccccaa ttggaacctg ggatcaagtg gccgaggtcc     1740

tgagctggca gttctcctcc accaccaagc gaggactgag catcgagcag ctgactacac     1800

tggcagagaa actcttggga cctggtgtga attattcagg gtgtcagatc acatgggcta     1860

aattttgcaa agaaaacatg gctggcaagg gcttctcctt ctgggtctgg ctggacaata     1920

tcattgacct tgtgaaaaag tacatcctgg ccctttggaa cgaagggtac atcatgggct     1980

ttatcagtaa ggagcgggag cgggccatct tgagcactaa gcctccaggc accttcctgc     2040

taagattcag tgaaagcagc aaagaaggag gcgtcacttt cacttgggtg gagaaggaca     2100

tcagcggtaa gacccagatc cagtccgtgg aaccatacac aaagcagcag ctgaacaaca     2160

tgtcatttgc tgaaatcatc atgggctata agatcatgga tgctaccaat atcctggtgt     2220

ctccactggt ctatctctat cctgacattc ccaaggagga ggcattcgga aagtattgtc     2280

ggccagagag ccaggagcat cctgaagctg acccaggcgc tgccccatac ctgaagacca     2340

agtttatctg tgtgacacca acgacctgca gcaataccat tgacctgccg atgtcccccc     2400

gcactttaga ttcattgatg cagtttggaa ataatggtga aggtgctgaa ccctcagcag     2460

gagggcagtt tgagtccctc acctttgaca tggagttgac ctcggagtgc gctacctccc     2520

ccatgtgagg agctgagaac ggaagctgca gaaagatacg actgaggcgc ctacctgcat     2580

tctgccaccc ctcacacagc caaaccccag atcatctgaa actactaact ttgtggttcc     2640

agattttttt taatctccta cttctgctat ctttgagcaa tctgggcact tttaaaaata     2700

gagaaatgag tgaatgtggg tgatctgctt ttatctaaat gcaaataagg atgtgttctc     2760

tgagacccat gatcagggga tgtggcgggg ggtggctaga gggagaaaaa ggaaatgtct     2820

tgtgttgttt tgttcccctg ccctcctttc tcagcagctt tttgttattg ttgttgttgt     2880

tcttagacaa gtgcctcctg gtgcctgcgg catccttctg cctgtttctg taagcaaatg     2940

ccacaggcca cctatagcta catactcctg gcattgcact ttttaacctt gctgacatcc     3000

aaatagaaga taggactatc taagccctag gtttcttttt aaattaagaa ataataacaa     3060

ttaaagggca aaaaacactg tatcagcata gcctttctgt atttaagaaa cttaagcagc     3120

cgggcatggt ggctcacgcc tgtaatccca gcactttggg aggccgaggc ggatcataag     3180

gtcaggagat caagaccatc ctggctaaca cggtgaaacc ccgtctctac taaaagtaca     3240

aaaaattagc tgggtgtggt ggtgggcgcc tgtagtccca gctactcggg aggctgaggc     3300

aggagaatcg cttgaacctg agaggcggag gttgcagtga gccaaaattg caccactgca     3360

cactgcactc catcctgggc gacagtctga gactctgtct caaaaaaaaa aaaaaaaaaa     3420

agaaacttca gttaacagcc tccttggtgc tttaagcatt cagcttcctt caggctggta     3480

atttatataa tccctgaaac gggcttcagg tcaaaccctt aagacatctg aagctgcaac     3540

ctggcctttg gtgttgaaat aggaaggttt aaggagaatc taagcatttt agactttttt     3600

ttataaatag acttattttc ctttgtaatg tattggcctt ttagtgagta aggctgggca     3660

gagggtgctt acaaccttga ctccctttct ccctggactt gatctgctgt ttcagaggct     3720

aggttgtttc tgtgggtgcc ttatcagggc tgggatactt ctgattctgg cttccttcct     3780

gccccaccct cccgacccca gtccccctga tcctgctaga ggcatgtctc cttgcgtgtc     3840

taaaggtccc tcatcctgtt tgttttagga atcctggtct caggacctca tggaagaaga     3900

gggggagaga gttacaggtt ggacatgatg cacactatgg ggccccagcg acgtgtctgg     3960

ttgagctcag ggaatatggt tcttagccag tttcttggtg atatccagtg gcacttgtaa     4020

tggcgtcttc attcagttca tgcagggcaa aggcttactg ataaacttga gtctgccctc     4080

gtatgagggt gtatacctgg cctccctctg aggctggtga ctcctccctg ctggggcccc     4140

acaggtgagg cagaacagct agagggcctc cccgcctgcc cgccttggct ggctagctcg     4200

cctctcctgt gcgtatggga acacctagca cgtgctggat gggctgcctc tgactcagag     4260

gcatggccgg atttggcaac tcaaaaccac cttgcctcag ctgatcagag tttctgtgga     4320

attctgtttg ttaaatcaaa ttagctggtc tctgaattaa gggggagacg accttctcta     4380

agatgaacag ggttcgcccc agtcctcctg cctggagaca gttgatgtgt catgcagagc     4440

tcttacttct ccagcaacac tcttcagtac ataataagct taactgataa acagaatatt     4500

tagaaaggtg agacttgggc ttaccattgg gtttaaatca tagggaccta gggcgagggt     4560

tcagggcttc tctggagcag atattgtcaa gttcatggcc ttaggtagca tgtatctggt     4620

cttaactctg attgtagcaa aagttctgag aggagctgag ccctgttgtg gcccattaaa     4680

gaacagggtc ctcaggccct gcccgcttcc tgtccactgc cccctcccca tccccagccc     4740

agccgaggga atcccgtggg ttgcttacct acctataagg tggtttataa gctgctgtcc     4800

tggccactgc attcaaattc caatgtgtac ttcatagtgt aaaaatttat attattgtga     4860

ggttttttgt cttttttttt tttttttttt tttggtatat tgctgtatct actttaactt     4920

ccagaaataa acgttatata ggaaccgtaa aaa                                  4953


<210>  2096
<211>  2105
<212>  DNA
<213>  homo sapiens

<400>  2096
cggaccctcc cgcggccgac tggaggcccg gagcaggggc ggagtttccg gcggcagcgc       60

cactcgggcg tcgggtgacg ctaggcggac ggaccatcat gtgacacgga agtagctccg      120

aacaggaaga ggacgaaaaa aataaccgtc cgcgacgccg agacaaaccg gacccgcaac      180

caccatgaac agcaaaggtc aatatccaac acagccaacc taccctgtgc agcctcctgg      240

gaatccagta taccctcaga ccttgcatct tcctcaggct ccaccctata ccgatgctcc      300

acctgcctac tcagagctct atcgtccgag ctttgtgcac ccaggggctg ccacagtccc      360

caccatgtca gccgcatttc ctggagcctc tctgtatctt cccatggccc agtctgtggc      420

tgttgggcct ttaggttcca caatccccat ggcttattat ccagtcggtc ccatctatcc      480

acctgcctcc acctcctgga tgccctccca atgctgctca gcttgcagtc atgcagggag      540

ccaacgtcct cgtaactcag cggaagggga acttcttcat gggtggttca gatggtggct      600

acaccatctg gtgaggaacc aaggccacct ctgtgccggg aaagacatca cataccttca      660

gcacttctca caatgtaact gctttagtca tattaacctg aagttgcagt ttagacacat      720

gttgttgggg tgtctttctg gtgcccaaac tttcaggcac ttttcaaatt taataaggaa      780

ccatgtaatg gtagcagtac ctccctaaag cattttgagg taggggaggt atccattcat      840

aaaatgaatg tgggtgaagc cgccctaagg attttccttt aatttctctg gagtaatact      900

gtaccatact ggtctttgct tttagtaata aaacatcaaa ttaggtttgg agggaacttt      960

gatcttccta agaattaaag ttgccaaatt attctgattg gtctttaatc tcctttaagt     1020

ctttgatata tattacttgt tataaatgga acgcattagt tgtctgcctt ttcctttcca     1080

tcccttgccc cacccatccc atctccaacc ctagtcttcc atttcctccc gccagtctcc     1140

attgaatcaa tggtgcagga cagaaagcca gtcagactaa tttccttctt tcctcgcact     1200

tctccccact cgtcatcttt taactagtgt ttcacaagga tcctctgaaa ccctctctgt     1260

gccccaagta cagatgccat tacttctgct ttcgtatctc ctcaggcaaa agtggagggt     1320

gccttatggg ccctcctcat aggttgtctc tgcatacacg aacctaaccc aaatttgctt     1380

tggtgccaga aaaactgagc tatgtttgaa caaagatgtc gtgcaaactg tactgtgaac     1440

aacagttggt ttaaaatatg aggggcaagg aggaggatgc atttcaaaag cttgattgat     1500

gtgttcagag ctaaattaag aggagttttc agatcaaaaa ctggttacca ttttttgtca     1560

gagtgtctga tgcggccact cattcggctc cccagaattc ctagactggg ttaatagggt     1620

catattgtga atgtctcact acaaaatgac ttgagtccag tgaaatctca ttagggttta     1680

agaatatttc agggatcctt aatgttttga tttttgtttt ctgaaattgg attttatttt     1740

attttatctt ataatttcag ttcatctaaa ttgtgtgttc tgtacatgtg atgtttgact     1800

gtaccattga ctgttatgga agttcagcgt tgtatgtctc tctctacact gtggtgcact     1860

taacttgtgg aatttttata ctaaaaatgt agaataaaga ctattttgaa gatttgaata     1920

aagtgatgaa gttgcattac acctcactgc aaggattctt tacttagctt gtttttagat     1980

ttcttctata tatattttat ttatatccca tctagaattc agctaggtgc tgctgctgct     2040

ctgtttcctt tgatgacgct ttgaaataaa ggcaggagta caagcctaaa aaaaaaaaaa     2100

aaaaa                                                                 2105


<210>  2097
<211>  1936
<212>  DNA
<213>  homo sapiens

<400>  2097
cggaccctcc cgcggccgac tggaggcccg gagcaggggc ggagtttccg gcggcagcgc       60

cactcgggcg tcgggtgacg ctaggcggac ggaccatcat gtgacacgga agtagctccg      120

aacaggaaga ggacgaaaaa aataaccgtc cgcgacgccg agacaaaccg gacccgcaac      180

caccatgaac agcaaaggtc aatatccaac acagccaacc taccctgtgc agcctcctgg      240

gaatccagta taccctcaga ccttgcatct tcctcaggct ccaccctata ccgatgctcc      300

acctgcctac tcagagcctc cacctcctgg atgccctccc aatgctgctc agcttgcagt      360

catgcaggga gccaacgtcc tcgtaactca gcggaagggg aacttcttca tgggtggttc      420

agatggtggc tacaccatct ggtgaggaac caaggccacc tctgtgccgg gaaagacatc      480

acataccttc agcacttctc acaatgtaac tgctttagtc atattaacct gaagttgcag      540

tttagacaca tgttgttggg gtgtctttct ggtgcccaaa ctttcaggca cttttcaaat      600

ttaataagga accatgtaat ggtagcagta cctccctaaa gcattttgag gtaggggagg      660

tatccattca taaaatgaat gtgggtgaag ccgccctaag gattttcctt taatttctct      720

ggagtaatac tgtaccatac tggtctttgc ttttagtaat aaaacatcaa attaggtttg      780

gagggaactt tgatcttcct aagaattaaa gttgccaaat tattctgatt ggtctttaat      840

ctcctttaag tctttgatat atattacttg ttataaatgg aacgcattag ttgtctgcct      900

tttcctttcc atcccttgcc ccacccatcc catctccaac cctagtcttc catttcctcc      960

cgccagtctc cattgaatca atggtgcagg acagaaagcc agtcagacta atttccttct     1020

ttcctcgcac ttctccccac tcgtcatctt ttaactagtg tttcacaagg atcctctgaa     1080

accctctctg tgccccaagt acagatgcca ttacttctgc tttcgtatct cctcaggcaa     1140

aagtggaggg tgccttatgg gccctcctca taggttgtct ctgcatacac gaacctaacc     1200

caaatttgct ttggtgccag aaaaactgag ctatgtttga acaaagatgt cgtgcaaact     1260

gtactgtgaa caacagttgg tttaaaatat gaggggcaag gaggaggatg catttcaaaa     1320

gcttgattga tgtgttcaga gctaaattaa gaggagtttt cagatcaaaa actggttacc     1380

attttttgtc agagtgtctg atgcggccac tcattcggct ccccagaatt cctagactgg     1440

gttaataggg tcatattgtg aatgtctcac tacaaaatga cttgagtcca gtgaaatctc     1500

attagggttt aagaatattt cagggatcct taatgttttg atttttgttt tctgaaattg     1560

gattttattt tattttatct tataatttca gttcatctaa attgtgtgtt ctgtacatgt     1620

gatgtttgac tgtaccattg actgttatgg aagttcagcg ttgtatgtct ctctctacac     1680

tgtggtgcac ttaacttgtg gaatttttat actaaaaatg tagaataaag actattttga     1740

agatttgaat aaagtgatga agttgcatta cacctcactg caaggattct ttacttagct     1800

tgtttttaga tttcttctat atatatttta tttatatccc atctagaatt cagctaggtg     1860

ctgctgctgc tctgtttcct ttgatgacgc tttgaaataa aggcaggagt acaagcctaa     1920

aaaaaaaaaa aaaaaa                                                     1936


<210>  2098
<211>  5253
<212>  DNA
<213>  homo sapiens

<400>  2098
ctttggaggt tcagagctgc aagaagatgg ggactggtgt cggggcgcca gcgcctgacc       60

cgctggggtt gcggccgggg tggagagtgc tgctggccgc cagttgttcc ggagacggtg      120

caaacggacg gggaaagtgt cggggtctgg ctcgcaaaat ttatctccgc atctcttccc      180

acaacacttg caccctctgc cccccaaaat ctttctggag acacagaaaa gggtcaaccg      240

agtcgcccta ctaagagcaa ggatgcccac gtctgtggcc ggtgctgtgc cgagttcttt      300

gaattatcag atcttctgct ccacaagaag aactgtacta aaaatcaatt agttttaatc      360

gtaaatgaaa atccagcctc cccacccgaa accttctccc ccagcccccc tcctgataat      420

cctgatgaac aaatgaatga cacagttaac aaaacagatc aagtggactg cagcgacctt      480

tcagaacaca acggacttga cagggaagag tccatggagg tggaggcccc ggttgctaac      540

aaaagcggca gcggcacttc cagcggcagc cacagcagta ccgccccaag cagcagcagc      600

agcagcagca gcagcagcgg cggcggcggc agctcctcca caggtacctc agcgatcaca      660

acctctctac ctcaactcgg ggacctgaca acactgggca acttctccgt aatcaacagc      720

aacgtcatca tcgagaacct ccagagcacc aaggtggcgg tggcccagtt ctcccaggaa      780

gcgaggtgcg gcggggcctc tgggggcaag ctggccgtcc cagccctcat ggaacaactc      840

ctagctctgc agcagcagca gatccaccag ctgcaattga tcgaacagat tcgtcaccaa      900

atattgctgt tggcttctca gaatgcagac ttgccaacat cttctagtcc ttctcaaggt      960

actttacgaa catctgccaa ccccttgtcc acgctaagtt cccatttatc tcagcagctg     1020

gcagcagcag ctggattggc acagagcctc gccagccaat ctgccagcat tagtggtgtg     1080

aaacagctac ccccaatcca gctacctcag agcagttctg gcaacaccat cattccatcc     1140

aacagcggct cttctcccaa tatgaacata ttggcagcgg cagttaccac cccgtcctct     1200

gaaaaagtgg cttcaagtgc tggggcctcc catgtcagca acccagcggt ctcatcatcg     1260

tcctcaccag cttttgcaat aagcagttta ttaagtcctg cgtctaatcc acttctacct     1320

cagcaagcct ccgctaactc ggttttcccc agccctttgc ccaacatcgg aacaactgca     1380

gaggatttaa actccttgtc tgccttggcc cagcaaagaa aaagcaagcc accaaatgtc     1440

actgcctttg aagcgaaaag tacttccgat gaggcattct tcaaacacaa gtgcaggttc     1500

tgcgcgaagg tctttgggag tgacagtgcc ttgcagatcc acttgcgttc ccataccgga     1560

gagaggccat tcaagtgcaa catctgcggg aacaggttct ccaccaaggg gaatctgaaa     1620

gtccactttc agcgccacaa agagaaatac cctcatatcc agatgaaccc ctatcctgtg     1680

cctgagcatt tggacaatat ccccacgagt actggcatcc catatggcat gtccatccct     1740

ccagagaagc cagtcaccag ctggctagac accaaaccag tcctgcctac tctgaccact     1800

tcagtcggcc tgccgttgcc cccaaccctc ccaagcctca tacccttcat caagacggaa     1860

gagccagccc ccatccccat cagccattct gccaccagcc ccccaggctc agtcaaaagt     1920

gactccgggg gccctgagtc agccacaaga aacctaggtg ggctcccaga ggaagccgaa     1980

gggtccactc tgccaccctc tggtggcaaa agcgaagaga gtggcatggt caccaactca     2040

gtcccgacgg cgagcagtag cgtcctgagc tccccagcgg cagactgcgg ccccgcgggc     2100

agtgccacca ccttcaccaa ccctttgttg ccgctcatgt ccgagcagtt caaggccaag     2160

tttccttttg ggggactcct ggactcagct caggcatcag agacgtccaa gcttcagcaa     2220

ctggtagaaa acattgacaa gaaggccact gaccccaatg agtgcatcat ctgccaccgg     2280

gttctcagct gccagagcgc cttgaaaatg cactacagga cacacactgg ggagaggccc     2340

tttaagtgta agatctgtgg ccgggctttc accacgaaag ggaatcttaa aacccactac     2400

agtgtccatc gtgctatgcc cccgctcaga gtccagcatt cctgccccat ctgccagaag     2460

aagttcacga acgctgtggt cctgcagcag cacatccgaa tgcatatggg aggccagatc     2520

cccaacaccc cagtccccga cagctactct gagtccatgg agtctgacac aggttccttt     2580

gatgagaaaa attttgatga cctagacaac ttctctgatg aaaacatgga agactgtcct     2640

gagggcagca tccctgatac acctaagtct gcagacgcct cccaagacag cttatcctct     2700

tcgcctttgc ccctcgagat gtcgagcatc gctgctttgg aaaatcagat gaagatgatc     2760

aatgctggcc tggcagagca gctacaggcc agcctgaagt cagtggagaa tgggtccatc     2820

gagggggatg tcctgaccaa tgattcatcc tcagtgggtg gtgacatgga aagccaaagt     2880

gctggcagcc cagccatctc agagtctacc tcttccatgc aggctctgtc cccgtccaac     2940

agcacgcagg agttccacaa gtcacccagc attgaggaga aaccacagag agcggtccca     3000

agcgagtttg ccaatggttt gtctcccacc ccagtgaatg gtggggcttt ggatttgaca     3060

tctagtcacg cagagaaaat catcaaagaa gattctttgg ggatcctctt cccttttaga     3120

gaccggggta aatttaaaaa cactgcttgt gacatttgtg gcaaaacatt tgcttgtcag     3180

agtgccttgg acattcacta tagaagtcat accaaagaga gaccatttat ttgcacagtt     3240

tgcaatcgtg gcttttccac aaagggtaat ttgaagcagc acatgttgac acatcagatg     3300

cgagatctgc catcccagct ctttgagccc agttccaacc ttggccccaa tcagaactca     3360

gcggtgattc ccgccaactc gttgtcatct ctcatcaaga cagaggtcaa cggcttcgtg     3420

catgtttctc ctcaggacag taaggacacc cccaccagtc acgtcccgtc tgggcctctg     3480

tcttcctctg ccacatcccc agttctgctc cctgctctgc ccaggagaac tcccaagcag     3540

cactactgca acacatgtgg caaaaccttc tcctcatcga gtgccctgca gattcacgag     3600

agaactcaca ctggagagaa accctttgct tgcactattt gtggaagagc tttcacgact     3660

aaaggcaatc ttaaggtaca catgggcact cacatgtgga atagcacccc tgcacgacgg     3720

ggtcggcggc tctctgtgga tggccccatg acatttctag gaggcaatcc cgtcaagttc     3780

ccagaaatgt tccagaagga tttggcggca agatcaggaa gtggggatcc ttccagcttc     3840

tggaatcagt atgcagcagc gctctccaac gggctggcga tgaaggccaa cgagatctcc     3900

gtcattcaga acggtggcat ccctccaatt cctggaagcc tcggcagtgg gaacagctca     3960

cctgttagtg ggctgacggg aaacctggag aggctccaga actcagagcc caatgctccc     4020

ctggccggcc tggagaaaat ggcaagcagt gagaacggaa ccaacttccg cttcacccgc     4080

ttcgtggagg acagcaagga gatcgtcacg agttaaagca gctcgggctg gagacatagc     4140

attcattcct gttcagaatg cgacctatgg tggcctccta ctccttgccc cccaccccgc     4200

cccgcccctt ccttctgttc cccagatcta tgaactacaa cattatgaag acattctttt     4260

gtaccttgtt caactttaga gttctaagaa agcttattta ttagcgatat aaccttgctt     4320

tgcaaacaga atgcaagcgt taactttggt cttctgtatt ttggactaaa tactaattga     4380

ctagagtgct gtaaacttgc tgtaacattt atggcaattg caagttgccc tgctaggcag     4440

ttgtaatctg gcattaactt attttctata tccagtttaa tatgaatctg gtgttgatgc     4500

aatgcctcag tgatgcatta gatctctaat aaagtctgta tatacatgta cactttgatc     4560

ctgctggaaa attttatcag caaacacatt gtctaatctt tcaaaacaga tttaaggaaa     4620

ggactgaaag tacagactga acagtgtggt tctttgaaag gtttggtttt ttaattttta     4680

ttctaaaatt caaccttttt ttttgtcgat ttaaccattt ccattttgaa ctgctatttg     4740

tattgtgctt tttacttgag tcgtcttcaa tgttaataag tttctgtaca gtaataagca     4800

cgcagaattc tttagagaaa aagaaaacaa gcgttgtttt ggtagttgaa actgagacgt     4860

aacattttgc cttgtaggta tattcacgat agaaaatgtg tgctggaatt tcacaatgct     4920

gctaagtata gcatcttgaa caaccttcag tggagaaaat gtagatgctc ttgtatatac     4980

aataagaaat atcactttca ttcaaatgta catatgttcc ttacaagagc aaatgcttct     5040

tcttgatcaa gagagcaggt atagtgtttg tttattttgt cttaggtatg gaagaaaaaa     5100

attggactgt tacatgcact ttcttggaaa gttgaaagga aagggggggt ccaatttctt     5160

taacatttaa tacttactaa caacagagat actgtaattt tactcaagta atcaaataca     5220

ttttttttgc aacagataaa acaaaatact gtg                                  5253


<210>  2099
<211>  1640
<212>  DNA
<213>  homo sapiens

<400>  2099
ggcctgccga gtccgcggcg ttccccggct gcagccggga gggggccgag gagtgactga       60

gccccgggct gtgcagtccg acgccgactg aggcacgagc gggtgacgct gggcctgcag      120

cgcggagcag aaagcagaac ccgcagagtc ctccctgctg ctgtgtggac gacacgtggg      180

cacaggcaga agtgggccct gtgaccagct gcactggttt cgtggaagga agctccagga      240

ctggcgggat gggctcagcc tgtatcaaag tcaccaaata ctttctcttc ctcttcaact      300

tgatcttctt tatcctgggc gcagtgatcc tgggcttcgg ggtgtggatc ctggccgaca      360

agagcagttt catctctgtc ctgcaaacct cctccagctc gcttaggatg ggggcctatg      420

tcttcatcgg cgtgggggca gtcactatgc tcatgggctt cctgggctgc atcggcgccg      480

tcaacgaggt ccgctgcctg ctggggctgc tgaagcagga gatgggcggc atcgtgactg      540

agctcattcg agactacaac agcagtcgcg aggacagcct gcaggatgcc tgggactacg      600

tgcaggctca ggtgaagtgc tgcggctggg tcagcttcta caactggaca gacaacgctg      660

agctcatgaa tcgccctgag gtcacctacc cctgttcctg cgaagtcaag ggggaagagg      720

acaacagcct ttctgtgagg aagggcttct gcgaggcccc cggcaacagg acccagagtg      780

gcaaccaccc tgaggactgg cctgtgtacc aggagggctg catggagaag gtgcaggcgt      840

ggctgcagga gaacctgggc atcatcctcg gcgtgggcgt gggtgtggcc atcatcgagc      900

tcctggggat ggtcctgtcc atctgcttgt gccggcacgt ccattccgaa gactacagca      960

aggtccccaa gtactgaggc agctgctatc cccatctccc tgcctggccc ccaacctcag     1020

ggctcccagg ggtctccctg gctccctcct ccaggcctgc ctcccacttc actgcgaaga     1080

ccctcttgcc catcctgact gaaagtaggg ggctttctgg ggcctagcga tctctcctgg     1140

cctatccgct gccagccttg agccctggct gttctgtggt tcctctgctc accgcccatc     1200

agggttctct tagcaactca gagaaaaatg ctccccacag cgtccctggc gcaggtgggc     1260

tggacttcta cctgccctca agggtgtgta tattgtatag gggcaactgt atgaaaaatt     1320

ggggaggagg gggccgggcg cggtggctca cgcctgtaat cccagcactt tgggaggccg     1380

aggcgggtgg atcacgaggt caggagatcg agaccatcct ggctaacatg gtgaaacccc     1440

gtctctacta aaaatacaaa aaaaatttag ccgggcgcgg tggcgggcac ctgtagtccc     1500

agctacttgg gaggctgagg caggagaatg gtgtgaaccc gggagcggag gttgcagtga     1560

gctgagatcg tgctactgca ctccagcctg ggggacagaa agagactccg tctcaaaaaa     1620

aaaaaaaaaa aaaaaaaaaa                                                 1640


<210>  2100
<211>  4559
<212>  DNA
<213>  homo sapiens

<400>  2100
ggttggaatt ttggcgggtt cagctgtgaa cgaagaaggc gtcccggcat cggccaagat       60

tctacattgc tcatctgggc atctgagcct ccttcgaagt ttcctgtcac aactgtcctc      120

ttgacagcat ggatgaggag gaagacaatc tgtctctgct gaccgcactg ctggaagaaa      180

atgagtcagc cttggattgt aattcagaag aaaataactt cttgacgcgg gaaaatggcg      240

agcccgacgc atttgatgag ctctttgatg ccgacggcga cggtgaatct tatacagaag      300

aggctgatga tggagaaaca ggagagacaa gagacgaaaa ggaaaatctg gccactctct      360

ttggagatat ggaggactta acagatgaag aagaagttcc cgcatcacag tcaactgaaa      420

atagggtcct ccctgctcct gcccccaggc gagagaaaac gaatgaagag ttgcaagagg      480

aattaaggaa tttgcaagag caaatgaagg ccttacaaga gcagctaaaa gtaacaacaa      540

ttaaacagac agcaagccca gcccgtctgc aaaaatcccc tgagaagtct ccccggccac      600

ctcttaagga gaggagagtt cagagaattc aggagtcaac atgcttttct gcggagcttg      660

atgtccctgc gctaccaaga accaagaggg tggctcgaac accaaaggct tcacctccag      720

atcccaaaag ctcatcttca aggatgacaa gtgcaccctc ccaaccccta cagacgattt      780

ctcggaacaa acctagtggg ataactagag gtcaaattgt ggggacccca ggaagttctg      840

gggaaacgac tcaacccatc tgtgtggaag ccttctctgg tctgcggctc aggcggcctc      900

gagtatcctc cacagaaatg aacaagaaaa tgaccggccg aaaactgatc agactgtctc      960

agatcaagga aaagatggcc agagagaagc tggaagaaat agattgggtg acatttgggg     1020

ttatattgaa gaaggttacg ccacagagtg tgaatagtgg aaaaaccttc agcatatgga     1080

aactgaatga tcttcgtgac ctgacacaat gtgtgtcctt gttcttattt ggagaagttc     1140

acaaagcgct ctggaagacg gagcagggga ctgtcgtagg gatcctcaat gccaacccca     1200

tgaagcccaa ggatggttca gaggaggtgt gtttatctat cgatcatcct cagaaggtct     1260

taattatggg tgaagctctt gacctgggaa cctgtaaagc caagaagaag aatggagagc     1320

cgtgcacgca gactgtgaat ttgcgtgact gtgagtactg tcagtaccat gtccaggctc     1380

agtacaagaa gctcagcgca aagcgtgcgg atctgcagtc caccttctct ggaggacgaa     1440

ttccaaagaa gtttgcccgc agaggcacca gcctcaaaga acggctgtgc caagatggct     1500

tttactacgg aggggtttct tctgcctcgt atgcagcttc aattgcagca gctgtggctc     1560

ctaagaagaa gattcaaacc actctgagta atctggttgt taagggcaca aacttgatca     1620

tccaggaaac acggcaaaaa ctcggaatac cccagaagag cctgtcttgc tctgaggagt     1680

tcaaggaact gatggacctg ccgacgtgtg gagccaggaa cttaaaacaa catttagcca     1740

aagccacagc ttcagggatt atggggagcc caaaaccagc catcaagtcc atctcggcct     1800

cagcactctt gaagcaacag aagcagcgga tgttggagat gaggagaagg aaatcagaag     1860

aaatacagaa gcgatttctg cagagctcaa gtgaagttga gagcccagct gtgccatctt     1920

catcaagaca gccccctgct cagcctccac ggacaggatc cgagttcccc aggctggagg     1980

gagccccggc cacaatgacg cccaagctgg ggcgaggtgt cttggaagga gatgatgttc     2040

tcttttatga tgagtcacca ccaccaagac caaaactgag tgctttagca gaagccaaaa     2100

agttagctgc tatcaccaaa ttaagggcaa aaggccaggt tcttacaaaa acaaacccaa     2160

acagcattaa gaagaaacaa aaggaccctc aggacatcct ggaggtgaag gaacgtgtag     2220

aaaaaaacac catgttttct tctcaagctg aggatgaatt ggagcctgcc aggaaaaaaa     2280

ggagagaaca acttgcctat ctggaatctg aggaatttca gaaaatccta aaagcaaaat     2340

caaaacacac aggcatcctg aaagaggccg aggctgagat gcaggagcgc tactttgagc     2400

cactggtgaa aaaagaacaa atggaagaaa agatgagaaa catcagagaa gtgaagtgcc     2460

gtgtcgtgac atgcaagacg tgcgcctata cccacttcaa gctgctggag acctgcgtca     2520

gtgagcagca tgaataccac tggcatgatg gtgtgaagag gtttttcaaa tgtccctgtg     2580

gaaacagaag catctccttg gacagactcc cgaacaagca ctgcagtaac tgtggcctct     2640

acaaatggga acgggacgga atgctaaagg aaaagactgg tccaaagata ggaggagaaa     2700

ctctgttacc aagaggagaa gaacatgcta aatttctgaa cagccttaaa taacccgaac     2760

ttcagacatt ttcccacaga cttcctggcc tcctgtgact ctggaaagca aaggattggc     2820

tgtgtattgt ccattgattc ctgattgacg ccgtcaaaaa caaatgcttg ttaagcccat     2880

aagctttgcc tgcttacttt ctgccattgg gttggtttga taccacattt aacattgaca     2940

tttaagtgga aaaccaagtt atcattgtct tttctaagct cagtgtggat gattgcatta     3000

cttcattcac tgaagttttt gcccaaaaat tggaaggtaa acagagagct atgtttctgt     3060

atcttttggt tatagagtgt tcacttcttt atcataacaa aattctagtg tttatacgaa     3120

cacccagagg caaaagaatt tggcttaatt ctcactccag gtaagtagct taacttctgg     3180

gcttcagttt tctcatctgt aaaatcagga agattggact aagtgatcct gaaatgtatt     3240

ttttagcact ggatttctac aaataataaa actttcccat ctagataatg atgatcacat     3300

agtcttgatg tacggacatt aaaagccaga tttcttcatt caattctgtt atctctgttt     3360

tactctttga aattgatcaa gccactgaat cactttgcat ttcagtttat atatatagag     3420

agaaagaagg tgtctgctct tacattattg tggagccctg tgatagaaat atgtaaaatc     3480

tcatattatt ttttttttaa tttttttatt ttttatgaca gggtctcact atgtcaccct     3540

ggctggagtg cagtagtgcg atcgcggcac actgcagcct tggcttccct gggctcaagc     3600

agtcctccca cctcagtctc ccaaatagct aggactacag gcgtgcgtga ccaagcccag     3660

ctaatttttg cattttttgt agagatgggg ttttgccatg ttgctcaggc tggtctcaaa     3720

ctcctgagca ctagcaatcc acccacctct gtttccaaaa aaaaaaaaaa aatgaaaggt     3780

caacccctat gcaaattacc acagcaaagg tttcattcag gagattcttc catctgggca     3840

acctggtttt ccaaatatca tttgacctaa gtgaatgttg atactagcta aagattgggt     3900

aaattggttg aattattgta ttgaagcttg agctgtagct aaaagtaatt taggtttccc     3960

ctaagatgtt attatgttag ggacataaca cttttgggag gttgttgtgg gagatggttg     4020

atttaggttt tcaaaagcta gaaataaaat ttacatgcct tagatttcat aaaattctgc     4080

tctaattggg tggaaggtgc tgtatctaac ttgtgttcct cctaaggtta tgtcctaata     4140

actattcttt taggagtata cttctacttt atagaaggtt gcttttcttt ttaatttttt     4200

ctaacaaaga aaagaataaa gtatttatta ataagaacca gaaagcactt gaaactgatg     4260

tttttaatgg ctcatttagg gtagatttat ttatctcatt aacttaaaac agctatgtgt     4320

atgaaatagg tcacaacaga acttgaacac caggttggtg tctgagcaat ccctttctta     4380

tgggaaaaac aatgttcttg tttgaacaga gggtatcatt gcagtcagta ttcacgtgta     4440

tattgttata taagttgtat aatatgcttg taaaggctga gggtgagctg tatctggatg     4500

cctttttaca atttgatttt aacttttaaa ataaatttaa aacataaaaa aaaaaaaaa      4559


<210>  2101
<211>  3598
<212>  DNA
<213>  homo sapiens

<400>  2101
atctgtgatt ggctgaacgg accgacccgg aagggtggat gctctcagct ggctggcggg       60

aagattttac tcccgagtag cggaaagatc tgctcgaggc ctgggtgctt tggtgtcgga      120

gatccgagag tcggagatcg gagagtcgga cacaggacag tcggacaccg gacagtcaaa      180

caccggagag ttagaccggg cttctcggtg gggagaggct ctgggataac tactgttaca      240

gctttgaagg gtcaagggag gattggccac caaagcctgt ttattagcag ctgccatttg      300

ttgaaagaaa tttggattat tttagaaaca aatttggaaa gaaaaagaat ggcgtccgtt      360

tcagctctaa ctgaggaact ggattctata accagtgagc tacatgcagt agaaattcaa      420

attcaagaac ttacggaaag gcaacaagag cttattcaga aaaaaaaagt cctgacaaag      480

aaaataaagc agtgtttaga ggattctgat gccggggcaa gcaatgaata tgattcttca      540

cctgccgctt ggaataaaga agattttcca tggtctggta aagttaaaga tattctgcaa      600

aatgtcttta aactggaaaa gttcagacca cttcagcttg aaactattaa cgtaacaatg      660

gctggaaagg aggtatttct tgttatgcct acaggaggtg gaaagagctt atgttaccag      720

ttaccagcat tatgttcaga tggttttaca ctcgtcattt gcccattgat ctctcttatg      780

gaagaccaat taatggtttt aaaacaatta ggaatttcag caaccatgtt aaatgcttct      840

agttctaagg agcatgttaa atgggttcat gctgaaatgg taaataaaaa ctccgagtta      900

aagctgattt atgtgactcc agagaaaatt gcaaaaagca aaatgtttat gtcaagacta      960

gagaaagcct atgaagcaag gagatttact cgaattgctg tggatgaagt tcactgctgt     1020

agtcagtggg gacatgattt cagacctgat tataaggcac ttggtatctt aaagcggcag     1080

ttccctaacg catcactaat tgggctgact gcaactgcaa caaatcacgt tttgacggat     1140

gctcagaaaa ttttgtgcat tgaaaagtgt tttactttta cagcttcttt taataggcca     1200

aatctatatt atgaggttcg gcagaagccc tcaaacactg aagattttat tgaggatatt     1260

gtaaagctca ttaatgggag atacaaaggg caatcaggaa tcatatattg tttttctcag     1320

aaagactctg aacaagttac ggttagtttg cagaatctgg gaattcatgc aggtgcttac     1380

catgccaatt tggagccaga agataagacc acagttcata gaaaatggtc agccaatgaa     1440

attcaggtag tagtggcaac tgttgcattt ggtatgggaa ttgataagcc agatgtgagg     1500

tttgttatcc atcattcaat gagtaaatcc atggaaaatt attaccaaga gagtggacgt     1560

gcaggtcgag atgacatgaa agcagactgt attttgtact acggctttgg agatatattc     1620

agaataagtt caatggtggt gatggaaaat gtgggacagc agaagcttta tgagatggta     1680

tcatactgtc aaaacataag caaatgtcgt cgtgtgttga tggctcaaca ttttgatgaa     1740

gtatggaact cagaagcatg taacaaaatg tgcgataact gctgtaaaga cagtgcattt     1800

gaaagaaaga acataacaga gtactgcaga gatctaatca agatcctgaa gcaggcagag     1860

gaactgaatg aaaaactcac tccattgaaa ctgattgatt cttggatggg aaagggtgca     1920

gcaaaactga gagtagcagg tgttgtggct cccacacttc ctcgtgaaga tctggagaag     1980

attattgcac actttctaat acagcagtat cttaaagaag actacagttt tacagcttat     2040

gctaccattt cgtatttgaa aataggacct aaagctaatc ttctgaacaa tgaggcacat     2100

gctattacta tgcaagtgac aaagtccacg cagaactctt tcagggctga atcgtctcaa     2160

acttgtcatt ctgaacaagg tgataaaaag atggaggaaa aaaattcagg caacttccag     2220

aagaaggctg caaacatgct tcagcaatct ggttctaaga atacaggagc taagaaaaga     2280

aaaatcgatg atgcctgata tgaatgttac taaattttct aattaaagat ggtttatgca     2340

tgtatatgcc attatttttg tagttagaca atagttttta aaagaatttc atagatattt     2400

tatatgtatg gatctatatt ttcagagctt atctctgaag atctaaactt ttgagaatgt     2460

ttgaaaatta gagatcatga attatataat tttccagtat aaaacaaggg aaaaattttt     2520

atgtaaaacc ctttaaatgt aaaatatttg agaataagtt catacaatcg tcttaagttt     2580

tttatgcctt tatatactta gctatatttt ttcttttgac ataactatct ttttgaaagc     2640

aatattatac tgacagaggc tcactgagtg atactttaag ttaaatatgt agatcaagga     2700

tgtccaatct tttggcttcc ctgagccaca ttggaagaag aattgtcttg ggccgcacat     2760

aaaatatgct aacactgatg atagctgatg agcttaaaaa aaaaattgca agaaaaatct     2820

catgttttaa gaaagtttac aaaaaatgta aaatatttga gaataagttc atgtaattgt     2880

cttaagtttt ttatgccttt atatacttag ctatattttt tcttttgaca taaccatctt     2940

tttgaaagca atattatact gacagaggtt cactgagtga tactttaagt taaatatgta     3000

gatcagggat gtccaatctt ttggcttccc tgagccacat tggaagaaga attgtcttgg     3060

gccgcacata aaatatgcta acactgacga tagctgatga gcttaaaaaa aaaaaaattg     3120

caagaaaaat ctcatgtttt aagaaagttt acagatttgt gttgggctgc attcaaagct     3180

gttctgggct gcattagacc cgtgggctag agttggacaa gcttgtagat gatttcaggt     3240

tataaaacca gaagtacaat tcaacaaaaa aggagtaagt catcaatata aatattagca     3300

aacgagatat tgctacatct ctatttaaag taaaatacaa ccgattttaa agttcctgaa     3360

accatagcca tattttgaca tttcacaaag aatggttcta gtctactaga gtacatttgg     3420

ctaagtagat aacttaccta aatttgctcc aaagctaaat cacaagtaaa catatttatg     3480

tttaaaacac agaaataaat aacttaagat ttttatctaa gcggtcagtg ttgtattgga     3540

aagatatatc tataaataaa ctttgaactg atttcaaact taaaaaaaaa aaaaaaaa       3598


<210>  2102
<211>  5755
<212>  DNA
<213>  homo sapiens

<400>  2102
gagtcgcgca cgcgcgcccg ggactgcctg cccctctctg tgacttgcct gtgtgtgtgc       60

gtgtgtgtat gtgtgtgtgt gtgtgtgtgt gcgcgcgcgc gtgagtgaga gaggagagag      120

ggagaagaga gcgcgagaga gggtgagtgt gtgtgagtgc atgggagggt gctgaatatt      180

ccgagacact gggaccacag cggcagctcc gctgaaaact gcattcagcc agtcctccgg      240

acttctggag cggggacagg gcgcagggca tcagcagcca ccagcaggac ctgggaaata      300

gggattcttc tgcctccact tcaggtttta gcagcttggt gctaaattgc tgtctcaaaa      360

tgcagaggat ctaatttgca gaggaaaaca gccaaagaag gaagaggagg aaaaggaaaa      420

aaaaaggggt atattgtgga tgctctactt ttcttggaaa tgcaaaagat tatgcatatt      480

tctgtcctcc tttctcctgt tttatgggga ctgatttttg gtgtctcttc taacagcata      540

cagatagggg ggctatttcc taggggcgcc gatcaagaat acagtgcatt tcgagtaggg      600

atggttcagt tttccacttc ggagttcaga ctgacacccc acatcgacaa tttggaggtg      660

gcaaacagct tcgcagtcac taatgctttc tgctcccagt tttcgagagg agtctatgct      720

atttttggat tttatgacaa gaagtctgta aataccatca catcattttg cggaacactc      780

cacgtctcct tcatcactcc cagcttccca acagatggca cacatccatt tgtcattcag      840

atgagacccg acctcaaagg agctctcctt agcttgattg aatactatca atgggacaag      900

tttgcatacc tctatgacag tgacagaggc ttatcaacac tgcaagctgt gctggattct      960

gctgctgaaa agaaatggca agtgactgct atcaatgtgg gaaacattaa caatgacaag     1020

aaagatgaga tgtaccgatc actttttcaa gatctggagt taaaaaagga acggcgtgta     1080

attctggact gtgaaaggga taaagtaaac gacattgtag accaggttat taccattgga     1140

aaacatgtta aagggtacca ctacatcatt gcaaatctgg gatttactga tggagaccta     1200

ttaaaaatcc agtttggagg tgcaaatgtc tctggatttc agatagtgga ctatgatgat     1260

tcgttggtat ctaaatttat agaaagatgg tcaacactgg aagaaaaaga ataccctgga     1320

gctcacacaa caacaattaa gtatacttct gctctgacct atgatgccgt tcaagtgatg     1380

actgaagcct tccgcaacct aaggaagcaa agaattgaaa tctcccgaag ggggaatgca     1440

ggagactgtc tggcaaaccc agcagtgccc tggggacaag gtgtagaaat agaaagggcc     1500

ctcaaacagg ttcaggttga aggtctctca ggaaatataa agtttgacca gaatggaaaa     1560

agaataaact atacaattaa catcatggag ctcaaaacta atgggccccg gaagattggc     1620

tactggagtg aagtggacaa aatggttgtt acccttactg agctcccttc tggaaatgac     1680

acctctgggc ttgagaataa gactgttgtt gtcaccacaa ttttggaatc tccgtatgtt     1740

atgatgaaga aaaatcatga aatgcttgaa ggcaatgagc gctatgaggg ctactgtgtt     1800

gacctggctg cagaaatcgc caaacattgt gggttcaagt acaagttgac aattgttggt     1860

gatggcaagt atggggccag ggatgcagac acgaaaattt ggaatgggat ggttggagaa     1920

cttgtatatg ggaaagctga tattgcaatt gctccattaa ctattaccct tgtgagagaa     1980

gaggtgattg acttctcaaa gcccttcatg agcctcggga tatctatcat gatcaagaag     2040

cctcagaagt ccaaaccagg agtgttttcc tttcttgatc ctttagccta tgagatctgg     2100

atgtgcattg tttttgccta cattggggtc agtgtagttt tattcctggt cagcagattt     2160

agcccctacg agtggcacac tgaggagttt gaagatggaa gagaaacaca aagtagtgaa     2220

tcaactaatg aatttgggat ttttaatagt ctctggtttt ccttgggtgc ctttatgcgg     2280

caaggatgcg atatttcgcc aagatccctc tctgggcgca ttgttggagg tgtgtggtgg     2340

ttctttaccc tgatcataat ctcctcctac acggctaact tagctgcctt cctgactgta     2400

gagaggatgg tgtctcccat cgaaagtgct gaggatcttt ctaagcaaac agaaattgct     2460

tatggaacat tagactctgg ctccactaaa gagtttttca ggagatctaa aattgcagtg     2520

tttgataaaa tgtggaccta catgcggagt gcggagccct ctgtgtttgt gaggactacg     2580

gccgaagggg tggctagagt gcggaagtcc aaagggaaat atgcctactt gttggagtcc     2640

acgatgaacg agtacattga gcaaaggaag ccttgcgaca ccatgaaagt tggtggaaac     2700

ctggattcca aaggctatgg catcgcaaca cctaaaggat cctcattaag aaatgcggtt     2760

aacctcgcag tactaaaact gaatgaacaa ggcctgttgg acaaattgaa aaacaaatgg     2820

tggtacgaca aaggagagtg cggcagcggg ggaggtgatt ccaaggaaaa gaccagtgcc     2880

ctcagtctga gcaacgttgc tggagtattc tacatccttg tcgggggcct tggtttggca     2940

atgctggtgg ctttgattga gttctgttac aagtcaaggg ccgaggcgaa acgaatgaag     3000

gtggcaaaga atgcacagaa tattaaccca tcttcctcgc agaattcaca gaattttgca     3060

acttataagg aaggttacaa cgtatatggc atcgaaagtg ttaaaattta ggggatgacc     3120

ttgaatgatg ccatgaggaa caaggcaagg ctgtcaatta caggaagtac tggagaaaat     3180

ggacgtgtta tgactccaga atttcccaaa gcagtgcatg ctgtccctta cgtgagtcct     3240

ggcatgggaa tgaatgtcag tgtgactgat ctctcgtgat tgataagaac cttttgagtg     3300

ccttacacaa tggttttctt gtgtgtttat tgtcaaagtg gtgagaggca tccagtatct     3360

tgaagacttt tctttcagcc aagaattctt aaatatgtgg agttcatctt gaattgtaag     3420

gaatgattaa ttaaaacaca acatcttttt ctactcgagt tacagacaaa gcgtggtgga     3480

catgcacagc taacatggaa gtactataat ttacctgaag tctttgtaca gacaacaaac     3540

ctgtttctgc agccactatt gttagtctct tgattcataa tgacttaagc acacttgaca     3600

tcaactgcat caagatgtga catgttttat aaaaaaagga aaaaaaacat ttaaaactaa     3660

aaaatatttt taggtatttt cacaaacaaa ctggctttta aataaatttg cttccatatt     3720

ggttgaataa gacaaaaaca attaaactga gtgggaagtg aataaaaaaa ggctttaggt     3780

atcgattcca tatttttcaa agccaaatat gtaaatgcta aggaaagtaa acaaagagga     3840

gattccaatc ttgtaattta atattgttat taaaacttta atgtatccta ttctttaaca     3900

tttggtgtta atataaaatt acttggcaat gcttgacatt tgaaataaac atttttctat     3960

tgttttattg caagtggtcc aattaatttt gcttagctac agtttggtca taaatcaagt     4020

gagtttaaag acactaccaa gttgttaggt gcccagagaa aatttctccc ttttaaaaag     4080

gccaggtgat ttttcaaatg taatcttgcc cccaaagtaa tatctgaata tctttttgac     4140

atgtctaaat atatatatat ataaagaaat atttgttaac acaaaagcat ttgatctatg     4200

tagataaatg ctaatagatt taaaaagcta atattaacaa ataccagaat acgtgaagtt     4260

ccatttttaa agtgtttgag cttacagaag agaaacattc attttaaatg aagtaaaaaa     4320

tgccttgaaa gtaattcttt agatagttgc ccattgatta aattccaaaa actaaatatg     4380

tttttagctt taaaattata aaagctgtca taaactttat atattatgaa ttttaaaata     4440

tgtttgagtc tcctgcaata tagtttcatc ccattgacat caattaaaaa taaccctaat     4500

atattatttt tatatttatt cctcaggtgg aatggctatt ttaatatgcc cagtgtggat     4560

aaaatgtcac atttctgtaa cttttgacta aagagcctat atttatctag ttaatgaatt     4620

taaaggatct atctttccct tcataaaata cctcttattt ccattaaagc cccccaagtt     4680

taattaattt aggattttga atgattattg acatccaata gttattttta atatttgtat     4740

tcttgttatt tctggaagaa agcctttgtg tagcacttgg tattttgcaa agtgctttta     4800

aaacattctt acttaccgta tttcatagaa gggaaggaaa aatgtaaggt ttaacagtaa     4860

gcacttgcat tgaacatgga ggcatgtggt atcatgatat tcttcactaa atttagctgt     4920

ccctaatcac agatcctaag gtaatataat ataattttag tgcatttctc ctcatcagga     4980

atgctggagg tgcattttaa gttttaataa taagtgctag aatgaccaaa ttgcagacta     5040

attgtttcca tattgtactt aaaatgagtt tttaaaagtg aaaaagaaat gactatatac     5100

aatcaatgct atttattgta cctctgggcc tactcttcta aaaattgtag cttatcgatt     5160

tttctctgtc aagcttgaac taatgtaaat aattgaaata atgtaaagtt atattttcat     5220

gtttttatag atacaacatg acaagaatac ataatgtaag agtatttcaa ctatggataa     5280

tgttgattgg ataatgcaca tctcagttac aagcagtact catagtttaa tatccatgta     5340

acggtgcatc aatatattgc tatataaata tgtctgtgtg catataagtg aaaagtggtc     5400

aaacaagagt gatgacagct gtctaaaggt ttttttattc attttatata aaaactgtta     5460

tggaaagacc aaaatgttta tgaactattc ttatgtaaat ttacaattgt cctttactgt     5520

acttttttgt ttacagtata gtaccttatt ttctgctgtg ttaagtgggt gtcaaactcc     5580

aagaagacat acactttcta taacttctat tgaagatatt ggaatttcca atttttcatg     5640

tgtactatgt cagaaaatgc tttcgatttt atttttaaat ctaacatcgg atggcttttc     5700

cggagtgttg taaaaacttc aatcatacat aaaacatgtt cttacaaaag gcaaa          5755


<210>  2103
<211>  4922
<212>  DNA
<213>  homo sapiens

<400>  2103
agcagagctg cggccggggg aacccagttt ccgaggaact tttcgccggc gccgggccgc       60

ctctgaggcc agggcaggac acgaacgcgc ggagcggcgg cggcgactga gagccggggc      120

cgcggcggcg ctccctagga agggccgtac gaggcggcgg gcccggcggg cctcccggag      180

gaggcggctg cgccatggac gagccaccct tcagcgaggc ggctttggag caggcgctgg      240

gcgagccgtg cgatctggac gcggcgctgc tgaccgacat cgaagacatg cttcagctta      300

tcaacaacca agacagtgac ttccctggcc tatttgaccc accctatgct gggagtgggg      360

cagggggcac agaccctgcc agccccgata ccagctcccc aggcagcttg tctccacctc      420

ctgccacatt gagctcctct cttgaagcct tcctgagcgg gccgcaggca gcgccctcac      480

ccctgtcccc tccccagcct gcacccactc cattgaagat gtacccgtcc atgcccgctt      540

tctcccctgg gcctggtatc aaggaagagt cagtgccact gagcatcctg cagaccccca      600

ccccacagcc cctgccaggg gccctcctgc cacagagctt cccagcccca gccccaccgc      660

agttcagctc cacccctgtg ttaggctacc ccagccctcc gggaggcttc tctacaggaa      720

gccctcccgg gaacacccag cagccgctgc ctggcctgcc actggcttcc ccgccagggg      780

tcccgcccgt ctccttgcac acccaggtcc agagtgtggt cccccagcag ctactgacag      840

tcacagctgc ccccacggca gcccctgtaa cgaccactgt gacctcgcag atccagcagg      900

tcccggtcct gctgcagccc cacttcatca aggcagactc gctgcttctg acagccatga      960

agacagacgg agccactgtg aaggcggcag gtctcagtcc cctggtctct ggcaccactg     1020

tgcagacagg gcctttgccg accctggtga gtggcggaac catcttggca acagtcccac     1080

tggtcgtaga tgcggagaag ctgcctatca accggctcgc agctggcagc aaggccccgg     1140

cctctgccca gagccgtgga gagaagcgca cagcccacaa cgccattgag aagcgctacc     1200

gctcctccat caatgacaaa atcattgagc tcaaggatct ggtggtgggc actgaggcaa     1260

agctgaataa atctgctgtc ttgcgcaagg ccatcgacta cattcgcttt ctgcaacaca     1320

gcaaccagaa actcaagcag gagaacctaa gtctgcgcac tgctgtccac aaaagcaaat     1380

ctctgaagga tctggtgtcg gcctgtggca gtggagggaa cacagacgtg ctcatggagg     1440

gcgtgaagac tgaggtggag gacacactga ccccaccccc ctcggatgct ggctcacctt     1500

tccagagcag ccccttgtcc cttggcagca ggggcagtgg cagcggtggc agtggcagtg     1560

actcggagcc tgacagccca gtctttgagg acagcaaggc aaagccagag cagcggccgt     1620

ctctgcacag ccggggcatg ctggaccgct cccgcctggc cctgtgcacg ctcgtcttcc     1680

tctgcctgtc ctgcaacccc ttggcctcct tgctgggggc ccgggggctt cccagcccct     1740

cagataccac cagcgtctac catagccctg ggcgcaacgt gctgggcacc gagagcagag     1800

atggccctgg ctgggcccag tggctgctgc ccccagtggt ctggctgctc aatgggctgt     1860

tggtgctcgt ctccttggtg cttctctttg tctacggtga gccagtcaca cggccccact     1920

caggccccgc cgtgtacttc tggaggcatc gcaagcaggc tgacctggac ctggcccggg     1980

gagactttgc ccaggctgcc cagcagctgt ggctggccct gcgggcactg ggccggcccc     2040

tgcccacctc ccacctggac ctggcttgta gcctcctctg gaacctcatc cgtcacctgc     2100

tgcagcgtct ctgggtgggc cgctggctgg caggccgggc agggggcctg cagcaggact     2160

gtgctctgcg agtggatgct agcgccagcg cccgagacgc agccctggtc taccataagc     2220

tgcaccagct gcacaccatg gggaagcaca caggcgggca cctcactgcc accaacctgg     2280

cgctgagtgc cctgaacctg gcagagtgtg caggggatgc cgtgtctgtg gcgacgctgg     2340

ccgagatcta tgtggcggct gcattgagag tgaagaccag tctcccacgg gccttgcatt     2400

ttctgacacg cttcttcctg agcagtgccc gccaggcctg cctggcacag agtggctcag     2460

tgcctcctgc catgcagtgg ctctgccacc ccgtgggcca ccgtttcttc gtggatgggg     2520

actggtccgt gctcagtacc ccatgggaga gcctgtacag cttggccggg aacccagtgg     2580

accccctggc ccaggtgact cagctattcc gggaacatct cttagagcga gcactgaact     2640

gtgtgaccca gcccaacccc agccctgggt cagctgatgg ggacaaggaa ttctcggatg     2700

ccctcgggta cctgcagctg ctgaacagct gttctgatgc tgcgggggct cctgcctaca     2760

gcttctccat cagttccagc atggccacca ccaccggcgt agacccggtg gccaagtggt     2820

gggcctctct gacagctgtg gtgatccact ggctgcggcg ggatgaggag gcggctgagc     2880

ggctgtgccc gctggtggag cacctgcccc gggtgctgca ggagtctgag agacccctgc     2940

ccagggcagc tctgcactcc ttcaaggctg cccgggccct gctgggctgt gccaaggcag     3000

agtctggtcc agccagcctg accatctgtg agaaggccag tgggtacctg caggacagcc     3060

tggctaccac accagccagc agctccattg acaaggccgt gcagctgttc ctgtgtgacc     3120

tgcttcttgt ggtgcgcacc agcctgtggc ggcagcagca gcccccggcc ccggccccag     3180

cagcccaggg caccagcagc aggccccagg cttccgccct tgagctgcgt ggcttccaac     3240

gggacctgag cagcctgagg cggctggcac agagcttccg gcccgccatg cggagggtgt     3300

tcctacatga ggccacggcc cggctgatgg cgggggccag ccccacacgg acacaccagc     3360

tcctcgaccg cagtctgagg cggcgggcag gccccggtgg caaaggaggc gcggtggcgg     3420

agctggagcc gcggcccacg cggcgggagc acgcggaggc cttgctgctg gcctcctgct     3480

acctgccccc cggcttcctg tcggcgcccg ggcagcgcgt gggcatgctg gctgaggcgg     3540

cgcgcacact cgagaagctt ggcgatcgcc ggctgctgca cgactgtcag cagatgctca     3600

tgcgcctggg cggtgggacc actgtcactt ccagctagac cccgtgtccc cggcctcagc     3660

acccctgtct ctagccactt tggtcccgtg cagcttctgt cctgcgtcga agctttgaag     3720

gccgaaggca gtgcaagaga ctctggcctc cacagttcga cctgcggctg ctgtgtgcct     3780

tcgcggtgga aggcccgagg ggcgcgatct tgaccctaag accggcggcc atgatggtgc     3840

tgacctctgg tggccgatcg gggcactgca ggggccgagc cattttgggg ggcccccctc     3900

cttgctctgc aggcacctta gtggcttttt tcctcctgtg tacagggaag agaggggtac     3960

atttccctgt gctgacggaa gccaacttgg ctttcccgga ctgcaagcag ggctctgccc     4020

cagaggcctc tctctccgtc gtgggagaga gacgtgtaca tagtgtaggt cagcgtgctt     4080

agcctcctga cctgaggctc ctgtgctact ttgccttttg caaactttat tttcatagat     4140

tgagaagttt tgtacagaga attaaaaatg aaattattta taatctgggt tttgtgtctt     4200

cagctgatgg atgtgctgac tagtgagagt gcttgggccc tcccccagca cctagggaaa     4260

ggcttcccct ccccctccgg ccacaaggta cacaactttt aacttagctc ttcccgatgt     4320

ttgtttgtta gtgggaggag tggggagggc tggctgtatg gcctccagcc tacctgttcc     4380

ccctgctccc agggcacatg gttgggctgt gtcaaccctt agggcctcca tggggtcagt     4440

tgtcccttct cacctcccag ctctgtcccc atcaggtccc tgggtggcac gggaggatgg     4500

actgacttcc aggacctgtt gtgtgacagg agctacagct tgggtctccc tgcaagaagt     4560

ctggcacgtc tcacctcccc catcccggcc cctggtcatc tcacagcaaa gaagcctcct     4620

ccctcccgac ctgccgccac actggagagg gggcacaggg gcgggggagg tttcctgttc     4680

tgtgaaaggc cgactccctg actccattca tgcccccccc cccagcccct cccttcattc     4740

ccattcccca acctaaagcc tggcccggct cccagctgaa tctggtcgga atccacgggc     4800

tgcagatttt ccaaaacaat cgttgtatct ttattgactt tttttttttt ttttttctga     4860

atgcaatgac tgttttttac tcttaaggaa aataaacatc ttttagaaac aaaaaaaaaa     4920

aa                                                                    4922


<210>  2104
<211>  2056
<212>  DNA
<213>  homo sapiens

<400>  2104
aaccgaaaag caacagctga tggcaaatcc gctccggcgc ttgcacgcct cctcggcggc       60

agtctcctgt tgcttctcgg agcttgactg ccctttggaa aaatctctcc gcccctcgag      120

aggagagagg agcagaggac gcgcgcgagc acagagcggg aggacggaca gggagaggag      180

gagagggggt ctgcgcgcgg ccgctaccca gaagccagcg gacggcagca cggagtgggc      240

tgtccccgag cccagccccg agcgagcccc ccccccgccc ccgcaggacg cgcctcccag      300

ccagcccgac tcctaggagg aggggaggcg ggaaagcagc tcaagcctca cccaccgccc      360

tgcccccagc cccgccactc ccaggctcct cgggactcgg cgggtcctcc tgggagtctc      420

ggaggggacc ggctgtgcag acgccatgga gttggtgctg gtcttcctct gcagcctgct      480

ggcccccatg gtcctggcca gtgcagctga aaaggagaag gaaatggacc cttttcatta      540

tgattaccag accctgagga ttgggggact ggtgttcgct gtggtcctct tctcggttgg      600

gatcctcctt atcctaagtc gcaggtgcaa gtgcagtttc aatcagaagc cccgggcccc      660

aggagatgag gaagcccagg tggagaacct catcaccgcc aatgcaacag agccccagaa      720

agcagagaac tgaagtgcag ccatcaggtg gaagcctctg gaacctgagg cggctgcttg      780

aacctttgga tgcaaatgtc gatgcttaag aaaaccggcc acttcagcaa cagccctttc      840

cccaggagaa gccaagaact tgtgtgtccc ccaccctatc ccctctaaca ccattcctcc      900

acctgatgat gcaactaaca cttgcctccc cactgcagcc tgcggtcctg cccacctccc      960

gtgatgtgtg tgtgtgtgtg tgtgtgtgtg actgtgtgtg tttgctaact gtggtctttg     1020

tggctacttg tttgtggatg gtattgtgtt tgttagtgaa ctgtggactc gctttcccag     1080

gcaggggctg agccacatgg ccatctgctc ctccctgccc ccgtggccct ccatcacctt     1140

ctgctcctag gaggctgctt gttgcccgag accagccccc tcccctgatt tagggatgcg     1200

tagggtaaga gcacgggcag tggtcttcag tcgtcttggg acctgggaag gtttgcagca     1260

ctttgtcatc attcttcatg gactcctttc actcctttaa caaaaacctt gcttccttat     1320

cccacctgat cccagtctga aggtctctta gcaactggag atacaaagca aggagctggt     1380

gagcccagcg ttgacgtcag gcaggctatg cccttccgtg gttaatttct tcccaggggc     1440

ttccacgagg agtccccatc tgccccgccc cttcacagag cgcccgggga ttccaggccc     1500

agggcttcta ctctgcccct ggggaatgtg tcccctgcat atcttctcag caataactcc     1560

atgggctctg ggaccctacc ccttccaacc ttccctgctt ctgagacttc aatctacagc     1620

ccagctcatc cagatgcaga ctacagtccc tgcaattggg tctctggcag gcaatagttg     1680

aaggactcct gttccgttgg ggccagcaca ccgggatgga tggagggaga gcagaggcct     1740

ttgcttctct gcctacgtcc ccttagatgg gcagcagagg caactcccgc atcctttgct     1800

ctgcctgtca gtggtcagag cggtgagcga ggtgggttgg agactcagca ggctccgtgc     1860

agcccttggg aacagtgaga ggttgaaggt cataacgaga gtgggaactc aacccagatc     1920

ccgcccctcc tgtcctctgt gttcccgcgg aaaccaacca aaccgtgcgc tgtgacccat     1980

tgctgttctc tgtatcgtga tctatcctca acaacaacag aaaaaaggaa taaaatatcc     2040

tttgtttcct agtggc                                                     2056


<210>  2105
<211>  2945
<212>  DNA
<213>  homo sapiens

<400>  2105
acactccagc cgctgagagc cccctttggc acttggcagc acgcggcggc gggctcctcg       60

gctcaacttc gaggagtctc cgcgacgcaa cttttgggga cgctttgcat ttaagagaga      120

acgaccgagg aggaggagcg ctctgcccgg ccgccgctac ctgcggggag ctcaccagca      180

aacgccactg cagacgaagg acccaaagaa cgtaaagggc aaactgccgc cgcggggagg      240

gggcaccgcc gagaagttag agtgtcccag agacaacctg ctcgagcgct cggccggaga      300

cactaaggcg gcccggggcg cggcgtggcc ctgggctggt cccccagccc cctcctccgg      360

ggcgggagcg acgccggggc gcgacgagcc ccggccggcc gagcgggtct ccgcgggcag      420

ccaacattga tttcctccgg gccgagggcg agggcccggg aggcggcggg ctgcagccgc      480

ggcagggcga gagcatgtcc aagccggtgg accacgtcaa gcggcccatg aacgccttca      540

tggtgtggtc gcgggctcag cggcgcaaga tggcccagga gaaccccaag atgcacaact      600

cggagatcag caagcgcttg ggcgccgagt ggaaactgct cacagagtcg gagaagcggc      660

cgttcatcga cgaggccaag cgtctacgcg ccatgcacat gaaggagcac cccgactaca      720

agtaccggcc gcggcgcaag cccaagacgc tgctcaagaa ggacaagttc gccttcccgg      780

tgccctacgg cctgggcggc gtggcggacg ccgagcaccc tgcgctcaag gcgggcgccg      840

ggctgcacgc gggggcgggc ggcggcctgg tgcctgagtc gctgctcgcc aatcccgaga      900

aggcggccgc ggccgccgcc gctgccgccg cacgcgtctt cttcccgcag tcggccgctg      960

ccgccgccgc tgccgccgcc gccgccgccg cgggcagccc ctactcgctg ctcgacctgg     1020

gctccaaaat ggcagagatc tcgtcgtcct cgtccggcct cccgtacgcg tcgtcgctgg     1080

gctacccgac cgcgggcgcg ggcgccttcc acggcgcggc ggcggcggct gcagcggcgg     1140

ccgccgccgc cggggggcac acgcactcgc accccagccc gggcaacccg ggctacatga     1200

tcccgtgcaa ctgcagcgcg tggcccagcc ccgggctgca gccgccgctc gcctacatcc     1260

tgctgccggg catgggcaag ccccagctgg acccctaccc cgcggcctac gctgccgcgc     1320

tatgaccccg cggggccgcc tcgcgaggac cggtgtgcac acgtgtacat atgtataggt     1380

acgagcgctg cggcctcccc gtgcgccctc ccgcgaccgg gggcccggtt tgtatgtaca     1440

tagaatgtat aggtgccagg tagaggcaga gaggccaggc ggggcaggag tggccaagcg     1500

cgcaagggcg cgggcgagca ggcctgtgaa ttcgcaggat catttcagac ccgcacttcg     1560

gcagccaact cgaaagcagg cggttgtgtg cggcagcagt tggcgtttgc tttgcacttc     1620

ggaacctgtt gcgttttgac ccacggaggt ggaggagtaa ctttttgaca tgttggcctt     1680

tccagttttg ttggaagttt catggtcggt tttgtttttg tttctcattc ttcttcctcg     1740

cccctcagcc ccccaacccc caaccccctc ccggtccgtg ttgcatgcac gctgttcaaa     1800

tgtgaggtct gaaatggctg gcacacggga aaagctgctt gtgtcattcg tttctgggag     1860

tgggatggct ctgagcagcc tcgcctccct gtttgtacta tttgaacttt gcagatctct     1920

gttctctcaa gcagaactcc caaccagatc cattcttgac cagtgaccgg ctcgaatctg     1980

gccttttgtg tgagatgatc acggtttctt ttgtttatca cgccatttgc aaatcagagc     2040

aagagctctt tctcaagggc aagaaacgca aacaagaaat atttgtgaga tgaaagttgt     2100

caattggatt ttcttcctaa acaaacaaca acaacaaact actagaagtc tccctgagtc     2160

cactcgcttg gatttctgac acagtttaca aaaaaggaaa aaggcactgc tcctattttc     2220

ccttatggct gagttcacct taagattgta aatgtgtata tgtcagtgaa aacattgagg     2280

cttggaaaat gtgttatttt cgttgcccta agtttgagtc gactttagac tcaaaaacat     2340

tttgagcgaa tatcaaagtt aacttttaaa aattgcgaaa ctatttcaga atcgcaattt     2400

tatcgaagat taaatcagac ttttttgtct ggtaattata tatttattat ttagcaaaac     2460

tgaagaaaaa aagcacagaa ttgtttcaac agatgtctct cattttcagc tagcatttct     2520

ctcccaagtt gagctggttt aatgtgtttt ggatttccct cctcaattgg cttatttttt     2580

agatcacctg caattcattt gcaaattgca ataaaacaca ttttagaaaa aaggaacctt     2640

caattattag ctttgtttct ttttaaatgt atatattttg actaatgttt gtgaatgaag     2700

ttggctaaca tgtatttagt ttcattttgg ctttatgtaa tataaagttt ttaaaatttt     2760

aaatatggtt ttaaccttta tgtgtaaatg attttctagt gtgaccttct aatttaatat     2820

tagacgtcta aggtatatct gtaaattaga atccgactat cactctgttc attttttttg     2880

aacaaagagt ttaaataaag cctgaaccag ggaaaagaaa aaaaaaaaaa aaaaaaaaaa     2940

aaaaa                                                                 2945


<210>  2106
<211>  10472
<212>  DNA
<213>  homo sapiens

<400>  2106
gctgacgacg catgcgccgg gagggggcgc aatcacggac tcggcttgcg gctgccggtt       60

taaaaaagga aaccccggag agcgagagcg cgaaggaaat ctggccgccg ccgccgcgag      120

cgctcccgaa tttttacttg ttcctgcaaa gctgctggag ctcagaagct gattctatca      180

cattgtaaga tgcctttgga taattctaca gtcctcttaa atgaatcttt agaacttggc      240

aagtctcact agataccttc aatcatcatt ttgagctcaa agaattctga gacttatggt      300

tggtcatata gaagagtacc ttgaacctat agtttcctga agaatcagtt taaaagatcc      360

aaggagtaca aaaggagaag tacaaatgtc tactacaaga cgaaaacgta gtatgttatg      420

ttgtttaccg taagctgtag taaaatgagc tcgattgttg acagagatga cagtagtatt      480

tttgatgggt tggtggaaga agatgacaag gacaaagcga aaagagtatc tagaaacaaa      540

tctgaaaaga aacgtagaga tcaatttaat gttctcatta aagaactggg atccatgctt      600

cctggtaatg ctagaaagat ggacaaatct actgttctgc agaaaagcat tgatttttta      660

cgaaaacata aagaaatcac tgcacagtca gatgctagtg aaattcgaca ggactggaaa      720

cctacattcc ttagtaatga agagtttaca caattaatgt tagaggctct tgatggtttt      780

tttttagcaa tcatgacaga tggaagcata atatatgtgt ctgagagtgt aacttcatta      840

cttgaacatt taccatctga tcttgtggat caaagtatat ttaattttat cccagaaggg      900

gaacattcag aggtttataa aatactctct actcatctgc tggaaagtga ttcattaacc      960

ccagaatatt taaaatcaaa aaatcagtta gaattctgtt gtcacatgct gcgaggaaca     1020

atagacccaa aggagccatc tacctatgaa tatgtaaaat ttataggaaa tttcaaatct     1080

ttaaacagtg tatcctcttc agcacacaat ggttttgaag gaactataca acgcacacat     1140

aggccatctt atgaagatag agtttgtttt gtagctactg tcaggttagc tacacctcag     1200

ttcatcaagg aaatgtgcac tgttgaagaa cccaatgaag agtttacatc tagacatagt     1260

ttagaatgga agtttctgtt tctagatcac agggcaccac ccataatagg gtatttgcca     1320

tttgaagttc tgggaacatc aggctatgat tactatcatg tggatgacct agaaaatttg     1380

gcaaaatgtc atgagcactt aatgcaatat gggaaaggca aatcatgtta ttataggttc     1440

ctgactaagg ggcaacagtg gatttggctt cagactcatt attatatcac ttaccatcag     1500

tggaattcaa ggccagagtt tattgtttgt actcacactg tagtaagtta tgcagaagtt     1560

agggctgaaa gacgacgaga acttggcatt gaagagtctc ttcctgagac agctgctgac     1620

aaaagccaag attctgggtc agataatcgt ataaacacag tcagtctcaa ggaagcattg     1680

gaaaggtttg atcacagccc aaccccttct gcctcttctc ggagttcaag aaaatcatct     1740

cacacggccg tctcagaccc ttcctcaaca ccaaccaaga tcccgacgga tacgagcact     1800

ccacccaggc agcatttacc agctcatgag aagatggtgc aaagaaggtc atcatttagt     1860

agtcagtcca taaattccca gtctgttggt tcatcattaa cacagccagt gatgtctcaa     1920

gctacaaatt taccaattcc acaaggcatg tcccagtttc agttttcagc tcaattagga     1980

gccatgcaac atctgaaaga ccaattggaa caacggacac gcatgataga agcaaatatt     2040

catcggcaac aagaagaact aagaaaaatt caagaacaac ttcagatggt ccatggtcag     2100

gggctgcaga tgtttttgca acaatcaaat cctgggttga attttggttc cgttcaactt     2160

tcttctggaa attcatctaa tatccagcaa cttgcaccta taaatatgca aggccaagtt     2220

gttcctacta accagattca aagtggaatg aatactggac acattggcac aactcagcac     2280

atgatacaac aacagacttt acagagtaca tcaactcaga gtcaacaaaa tgtactgagt     2340

gggcacagtc agcaaacatc tctacccagt cagacacaga gcactcttac agccccactg     2400

tataacacta tggtgatttc tcagcctgca gccggaagca tggtccagat tccatctagt     2460

atgccacaaa acagcaccca gagtgctgca gtaactacat tcactcagga caggcagata     2520

agattttctc aaggtcaaca acttgtgacc aaattagtga ctgctcctgt agcttgtggg     2580

gcagtcatgg tacctagtac tatgcttatg ggccaggtgg tgactgcata tcctactttt     2640

gctacacaac agcaacagtc acagacattg tcagtaacgc agcagcagca gcagcagagc     2700

tcccaggagc agcagctcac ttcagttcag caaccatctc aggctcagct gacccagcca     2760

ccgcaacaat ttttacagac ttctaggttg ctccatggga atccctcaac tcaactcatt     2820

ctctctgctg catttcctct acaacagagc accttccctc agtcacatca ccagcaacat     2880

cagtctcagc aacagcagca actcagccgg cacaggactg acagcttgcc cgacccttcc     2940

aaggttcaac cacagtagca cacgtgcttc ctctcttgac atcaagggag gaaggggatg     3000

gcccattaag agttactcag atgacctgag gaaaggaggg aaagttccag cagtttcatg     3060

agatgcagta ttgagtgttc tagttcctgg aattagttgg cagagaaaat gctgcctagt     3120

gctacagatg tacattaaat accagccagc aggaggtgat cataggggca tagccagttc     3180

tgacagtgtt ttaggtgcct ggatattttt tgatggaaaa agaatatatt gccaaatatt     3240

aagaagctca gctatgaaat gacctccagg gaatcagaaa ggcactaatg atgttagtaa     3300

cttttagtgg ttctgtgcct cttatcaagt gttacagagg acataccact gccatgtcag     3360

gggtttgctt acagtgatgc catgaagaca gtccagtaga cttggtagcg accccctccc     3420

ccaacccctc tcccttttca gataatgatg gaacagtaat tactttcaga atgttgtgtg     3480

ggttcaaatt ctctatgtac agatgatgta aaaatatgta tatgtctaga taaaaggaga     3540

gaaagcaaaa cattttgtat gctgcatgaa agcgttatct cttccttaca ggtgtgagca     3600

cctttcctga aattctgaca ccatgtgcaa actgatccat cctgtttttc cttttgttta     3660

caacacagta gtgttctgtt cacttttccg gggcacaagt ttttttgttc atactttggc     3720

tgtgatgtca cagtttgttc agtgaggtat gatgtgctgc tgggaatgga tttttttttt     3780

caggttaaat tattgataca acaggatttt caagttattc agaaatatcc ctcatttcat     3840

tatttttcaa ttatgtttga aaataggatt tgcactgctt tattttaggt ggctgggagt     3900

tttgattgca tattttgtta tagttcatag ttggaaatat ttgcgtaaat ggttttcaac     3960

aagcctgaaa gtaatttcaa gaatgtttca gttatagagg taaaatttgc acacaaaaca     4020

tcttaggcac tttttaacat tctcaatcat gggaatttta acttttggga tttgttgaaa     4080

tcttttttat tatccttcac aatttcaatg cttcttttag tcagaaatga ttcagggtta     4140

tttgagggga aaaaacccca tagtgccttg attttaattc aggtgataac tcaccatctt     4200

gaagtcattg tccggtttcc gtagcagttt tgaaacctta gtaccttttt aacagcatgt     4260

gggtgtcagt gtcattatta gtctcctaat aagttcctct gaagactgct atcagtctct     4320

tggactggag gtacaaataa tttagaaata aaagatgata acctaacact atcatagtta     4380

ttaatgtgat cctaaaattg tttcctaaat cagcattttt ctttagtcat ttaagaattt     4440

accagaaata tttgctcaat atgatcttga tattcctaca aagaaaaaag aaggggtagg     4500

gatttggcta tgccttcact acaacattag aatattgtaa ctcacatgcc ttctaaacgt     4560

gaactaagat ttcctttggc aatatcatat tctaaaagta ataaattcca atacaagtta     4620

catacattta aaaaacattt tacagatttt atggtactaa tgaaatttac agtgatagaa     4680

caaaagagga ttagtagaaa atacattatt agaatataaa aaatgttatt actgaggaaa     4740

gggaggagag gacaagtgta ataaatcaaa attgacctca aaagaaaatg tgtaacagag     4800

ttgaggttgt taaaacagaa aaggttctga ataatgaaga ttaacctaat gcagaattgc     4860

taggtaaaga ggtcagggga atgctaagcc agttcttaag acttctctgt cctctgcttt     4920

gctgttatcc ttaaggcata tactttgtct ttctgcagaa aattctacct ggctacaatt     4980

actttgaaca ttaatgttga aaaagaaaac aaccaaagaa aattggtact tacccttcta     5040

caaaagaagt gtgactagat atcaatcagt aattaacata tcaaggagct cttctagcta     5100

aatgaccatc cagtagagat ttcccacatt cccatgaata tcaagaatag ttgtcagaat     5160

atgtatgtac ctgagcatat gtacacagac aagggggatg ttgtggaata tggcaatagc     5220

attgttcttc tcccctttca aattgccttt cttgacctta tgccattcca tatatatctg     5280

agttgtgcct catttattta ttggcaatac ctagtgatac ggatttagct aacaaaagat     5340

atgaagaact attatattga ggcctgtcct ctacatacca cacttaaaag atggtgaact     5400

gtgagtacta cttaggttga cagcaacaaa gcataagaca agccccaggt aaacgtctaa     5460

actgtttact cacattgtcc tactccagcc ccttcaatta tttcccatct ccacaaatag     5520

tcgggggaaa aaattaaaat tttcctttat gattcttact gttcttcgca gctcatcttt     5580

tcctgcttag aattaaccat tgctaattta aaggagcagc tagctgcttt tctgtcagtc     5640

tgaagcgtag tagtggaaga ggtagtaagc accagctgcc tctttgctgc tttgttttcc     5700

tcctgattct cttaaatttg ggttgcaaag ctatcccgcc ccccaccctg ccccatgaaa     5760

cttgagcatt caaatgaaga ttcagcagtg tctgttcttc atttctatag ccaaagctgt     5820

tagttaaaat cccaaatcta tagcatttaa agataccaaa tagaaacacc ttccagcttt     5880

aaaaaaaaaa aaaaaaaagt cttccctctg ctttattctc actttcttaa aaacacttat     5940

tctgggtggt actttttagg taagaaacta ctgagtttca ggaaaaatgc tagctactct     6000

gcagttaccg tgctttggac ttgcagttat catagttttg ggagagtcag tattgtttaa     6060

caaatgcaag tgagaactag aagggttaat aaagttgctc cttagagtgg tgtcaaacca     6120

gaaccgagac acttaaaaag tacttcattt tttgaatgga aaatattgga gaaaagtatg     6180

ggagatgcag gtagcatgtg agtaaatact acggtctagc cttcgagcat cccaaattcc     6240

gggggtaact tgacagtgct gtgctctcct ttgtcattta tatctggctt aggaatggaa     6300

tagtaataac aagatgccag tgatttggaa tagtttgtta tagaacattc agtgcaaaat     6360

agtgaaaatg tttggtcttc agaagtgctg tagttgttgg tcattgcctt aaagcagtct     6420

gcttgacgct aggagcactg aagcagtcca gctccatcaa gagcactgtt gaagggagaa     6480

gaacccttgt tcaggaagcc ttagaaaggg atccttaaaa tagtactcta cgcagacaag     6540

tgaaaattct tttaaactgg atattactca acatgttttc agatgtttcc actacattga     6600

ggcaaacttt ttaaaagtgg aatgcaaata gcattttact ttagtatttc tgcttttttc     6660

tttctgtttc tttggtaatt gaaagtttgt tgatgaatat ttgtgtaaaa cgcattcaag     6720

tctataacct ttccaattac ctgtggccct tagtcccaca ggagtccctg ttggaagggg     6780

gtaaacactg gatattaatg ttgctgagtg agtctttcta gccaggacaa gctgattgga     6840

atttttgaat ggtagagaag aaacagcaca aaggcacttg ccattttaag tgtttggaga     6900

aagagaacct tttaagtttg gattgggtga gctttcttct aaaaggagct tctgaagtaa     6960

ttgcaaagga atagaatcga ctatttttat agtatattta atatatttgt atataactat     7020

aataggaacc ctctacatgc ctcccacttt tctaatttac ttcccctttt gccatagcac     7080

tagtatagcc tcatccgcat gggtaatgtg cctattgtca gcctaccaaa agatagtgct     7140

gctgctttat gagacaggtg agaagaccca actctcatgc ctggggatcc tttacggaag     7200

gaatagcaca cacttttaaa acaacatacc acagtctaaa agcatcattt tgaaatgtaa     7260

caagcacttt attgcaatta ctcattttga taaagtttat tcttaggcgt taaccatttc     7320

taaaggatcc ccaaatcatc acttacttag gtgaaattat ataaaatgac acatttctga     7380

gaaatgttta ggtccagtga accgtagttg gtttatggga gtgatttcaa gatagccaaa     7440

tgaactttga tttttgtttt gaatgtggtg gagtcaagag attgtagatg cctagtttga     7500

tttaaacact attgtaaacc tatcttgcct attgtgtgga caccaaaaga gaccaatgag     7560

cctgtttatt tttcagaggt ctaggaaaat tgcatccgtg tgagtagatg tacagaacta     7620

atctaaaagt gattgctagt aacattttag aatataataa tttcaagaat tattctgagt     7680

gttttaaatg tgccctgaaa tgttggcatg tcatttcagc atttccattt gaattgctct     7740

tgtaatattt ttgcacaaaa aggactgaga aaaagaatac tttggttaaa ggaaaaaaat     7800

agtataattt ggtctttaat tttaatgtct cctgtggaaa cactggggat gaattttgtt     7860

ggcacagtta ttcaggatat ttaaaacagt gttgaacagt tcacaagaaa ttaagcaaac     7920

ttggatttta aaaattaaaa tactttcttt ccatgtgact gttttgcata gttttttccc     7980

cctatgtcat aacactacat tccttgtttt tcttaaataa aatactctgc aggttttgtt     8040

gtgagtgttt ataacagtat tttgtaagct gcctgggttt cctcagggaa acattattta     8100

gtggaatagg atatagttta tggagagaca actaagtgaa attccatcac caccaccagc     8160

aaacactgag gtgctgcatt aagtgacaat caaactagta agtatttatg aaagaattta     8220

gaaaggggtt caaagaagca attgctttta aagcagttct ctggggttct tgaataaaaa     8280

tggctaaatg tatttattta tattttaaaa tacctgtgtg ttctgttttc tcatcaaagt     8340

gatttcggtg tcatgtattt aatgtgtggt ttgttttgtt ttgcaccata ttcttcttag     8400

ggaactggct ctgatttggg gtgcagtcac caactctcat gataatcttt acggacagtc     8460

tgaatctact ttacttcagg acggcagtgg aggggccaac tccagatgcc cctgcacttc     8520

cctcctcaag tcatctaaga aagaatttta gaaataactc ctttcaaatc tgattcatac     8580

agttccaacc tttttctagt ttcacttgct gccttctttg ttttatgggc actttttgtg     8640

tgattacttc cccaacacag tcaaaggcca gtatgacaga accaatggca catgatgcct     8700

ctattttgcc catttgggga aatgttagta aaagaaatag catcttttaa tggctgtcat     8760

tatcatatcc atattaaaat ccatttaaag ttcttaaatt tggcggaata atgtatacag     8820

gctgtaaact tctacaaaaa atgtttgctg tctttaatat ggtgtcaagt tacttggtcc     8880

tttgaaaaca aaacaaaact tccatacaca gcactgccca gtaaagcagt gttggaatat     8940

tggaaaccta gacatttgag gatccttctt gctcacaagc attggaacag aatcctccac     9000

tttaggactc agagaagcta tggagtccca caggctaggt atagcacaca acttagagaa     9060

cggtagttaa agcacgtcaa ccacaattga atttaatgat ctaaaaaata tttcttaact     9120

ctgagggtta aactgaagat acgttttcaa ataaaagctt ttaaatttct taggaaacaa     9180

actgtgacat cgcttttaaa aatgacattc aaatgtttat aatgtgtgtt tttgagttgg     9240

cttggactag tgcaagttca ctgctggcaa tggttatgcc agtagttaag ttaaaataag     9300

ttgttacctt cagattgatg tcttgtataa ccagacaatc atcttcaagc aaaaaaattg     9360

gccaggaaat gtctttttaa aaaaaaaaaa aaaaaaaaag atgtgtcagc cagaacagtt     9420

accattcaga ccatactgga atgattttga aatctttact atggtttaag ttggggaagg     9480

cctcagtatg gcattttcat attcactcta tgtaaagatt gaagcccaaa gatgagttaa     9540

attcagtgct gtattgaaac cagtcagtgc aaaaaaaaaa aaaaagtttt acctttgtaa     9600

atttttcatt gttaacatca gttggtagtt gttaaaacat gcaccaaatt ctttataatg     9660

ttctgtgtgg ttctcaatgt gatattcttg acattgctgt ccttactgct tggttcttgg     9720

ttttaaatta aaaagtagat gtagctcatc atttttactt ccaaaacggt ggagctaaaa     9780

acggctaatt gatcttgaga taagaatacc ctttactaag gcaaagattt aattgaaatc     9840

caaaatgatt tatagaaacg aaaggcattt tccatttgtt gtcttctgcc gaaattctga     9900

attgcataca cacatgaagg ataatgaatg gtttcaacgg tgctatatta ggttctctga     9960

ttttcatgac ctatgtatgt ttggaaatac aatattgtat aaaatgtgga tcgttttgtt    10020

accgatttaa tattgccatt ttaatttggt gtaacaattg gttacacttg tttttcaaag    10080

ctatcctttg aggagaaagt caaaatgtgt tgttagccta cctccactca ggcctcttgc    10140

tgtgtaatca ttattccagg ttatgatgtg catagctttt aaaactgcgt gtactattat    10200

tctgctcttt cccatactct tgtcatgtat tcagaaccta aacttatagc aaaagagcca    10260

agcagtagca gtttttgtaa atgtaaaaat aattagatcc agactttgtt tccttcaatt    10320

ttaaaaataa aaaatacctc agtgctatgt ttttcagtta tcacctgcat ttctcaaaaa    10380

ataacacctg cttcatgtgg cacataactt gtaagaatca cattttggat tttaaagaaa    10440

gactattaaa tattttaaga tcactatcaa tg                                  10472


<210>  2107
<211>  2660
<212>  DNA
<213>  homo sapiens

<400>  2107
ttttatttgg ggtttgggac cggatcaggc cttaaatcta cgcagaagaa aggcggagaa       60

gcagcggaag ccgggcacta gtcctgcagg gtggaaggcg ctttatcggg tcttctggcc      120

cgctgcgggc gatagagctg gtaacctgag tagagtaaat agagacacgt gggtgctggc      180

tagagaaagc gcggagcagg gccgcgctgg agggctgttt gaagcctagt ccagagctgg      240

tctagggggc ggatggaccc tgatacccga cactccactg gtcacccttg ttccacaact      300

gggaaaccct ctggaggaaa tccggtagaa aagtcctgac acccgaatga tttaaccaac      360

gccttttccc tccaaagaaa cttggaggat ataccttttt ttccttaaat ggcatctttc      420

tacccccaaa aagaaagtgt gtggttttga gggcggggac attttgggtt ttaaacagcg      480

cgtttaagaa cacctcagat ctgccttctc tatcccaatg gcagaggtgg ccagacaagc      540

acaaacctct caggagccct accacgacaa ggccagagaa caccccgatg acggaaagca      600

tccagatgga ggcctctaca acaagggacc ctcctactcg agttattccg ggtacataat      660

gatgccaaat atgaataacg acccatacat gtcaaatgga tctctttctc cacccatccc      720

gagaacatca aataaagtgc ccgtggtgca gccatcccat gcggtccatc ctctcacccc      780

cctcatcact tacagtgacg agcacttttc tccaggatca cacccgtcac acatcccatc      840

agatgtcaac tccaaacaag gcatgtccag acatcctcca gctcctgata tccctacttt      900

ttatcccttg tctccgggtg gtgttggaca gatcacccca cctcttggct ggttttccca      960

tcatatgatt cccggtcctc ctggtcccca cacaactggc atccctcatc cagctattgt     1020

aacacctcag gtcaaacagg aacatcccca cactgacagt gacctaatgc acgtgaagcc     1080

tcagcatgaa cagagaaagg agcaggagcc aaaaagacct cacattaaga agcctctgaa     1140

tgcttttatg ttatacatga aagaaatgag agcgaatgtc gttgctgagt gtactctaaa     1200

agaaagtgca gctatcaacc agattcttgg cagaaggtgg catgccctct cccgtgaaga     1260

gcaggctaaa tattatgaat tagcacggaa agaaagacag ctacatatgc agctttatcc     1320

aggctggtct gcaagagaca attatggtaa gaaaaagaag aggaagagag agaaactaca     1380

ggaatctgca tcaggtacag gtccaagaat gacagctgcc tacatctgaa acatggtgga     1440

aaacgaagct cattcccaac gtgcaaagcc aaggcagcga ccccaggacc tcttctggag     1500

atggaagctt gttgaaaacc cagactgtct ccacggcctg cccagtcgac cccaaaggaa     1560

cactgacatc aattttaccc tgaggtcact gctagagacg ctgatccata aagacaatca     1620

ctgccaaccc ctctttcgtc tactgcaaga gccaagttcc aaaataaagc ataaaaaggt     1680

tttttaaaag gaaatgtaaa agcacatgag aatgctagca ggctgtgggg cagctgagca     1740

gcttttctcc cctcatatct gcgtgcactt cccagagcat cttgcatcca aacctgtaac     1800

ctttcggcaa ggacggtaac ttggctgcat ttgcctgtca tgcgcaactg gagccagcaa     1860

ccagcacatc catcagcacc ccagtggagg agttcatgga agagttccct ctttgtttct     1920

gcttcatttt tctttctttt cttttctcct aaagctttta tttaacagtg caaaaggatc     1980

gttttttttt gcttttttaa acttgaattt ttttaattta cactttttag ttttaatttt     2040

cttgtatatt ttgctagcta tgagctttta aataaaattg aaagttctgg aaaagtttga     2100

aataatgaca taaaaagaag ccttcttttt ctgagacagc ttgtctggta agtggcttct     2160

ctgtgaattg cctgtaacac atagtggctt ctccgccctt gtaaggtgtt cagtagagct     2220

aaataaatgt aatagccaaa cccactctgt tggtagcaat tggcagccct atttcagttt     2280

attttttctt ctgttttctt cttttctttt tttaaacagt aaaccttaac agatgcgttc     2340

agcagactgg tttgcagtga attttcattt ctttccttat cacccccttg ttgtaaaaag     2400

cccagcactt gaattgttat tactttaaat gttctgtatt tgtatctgtt tttattagcc     2460

aattagtggg attttatgcc agttgttaaa atgagcattg atgtacccat tttttaaaaa     2520

agcaaggcac agcctttgcc caaaactgtc atcctaacgt ttgtcattcc agtttgagtt     2580

aatgtgctga gcattttttt aaaagaagct ttgtaataaa acatttttaa aaattgtcat     2640

ttaaaaaaaa aaaaaaaaaa                                                 2660


<210>  2108
<211>  7441
<212>  DNA
<213>  homo sapiens

<400>  2108
agaggagccg ggacaccgag ggaagaggcc ggagggagat cgcggagggg agggggcggg       60

aggggggtgg ggtatcctga gtcgtccgtg gtccggagtc tggaaggccc tagagcggcg      120

ccagtcgacc cgcctcgcca caacttgccc agaccagaca cgtttcatcc tgcgccctgc      180

aagaaggagc cggcctgcct ctctccgctt tgctgctcct cggcctccgc gggcccggcc      240

cgcgtcagca gcgaccctgg ggtctgggtc ccctgtgtcg cccccgcccg cctgcagcgc      300

ccggcacccg cccaggagcg cgcagctggg gttctaggga cgtatacttg agcaagagag      360

accacagctc ttgttcccgc tgatcctgca gcccagtgga tggagtccag aatctacaga      420

cctgccagga aagaaaaaaa aattcctgat gtctggtcca agcaggaatt ccccggtgga      480

ttggggaatg tctggctttt cctcagctta ttgatctctg tggtaaccac tggaggcccc      540

cagaagaccc atagaaatga gaggcctgag gtctacaagt cgctgctaga aatattttag      600

cctctccaaa gcccagaatg cagccccgac ccaagtttgt aagggttctg ggtgcacgct      660

gaccctgcgc gggcagacgc gccctttgct ccaggtccgg acctgggcgc tgctatagca      720

acgtcctgga cgcccagacc ttaggccgcc gccgccgcgg aagcgaggaa cccggccttc      780

tcccgctcct gagggctgtg gcggcggcgg cccgggaggc ggcccaggct gggtaaagac      840

cgcccggctc ctcctatgca agctgaggca gcggattggt tttcaagcat gcccttccag      900

aagcatgtct actacccgct cgccagcggc ccagaggggc ccgacgtcgc tgtggccgcc      960

gccgccgcgg gtgcggcctc catggcctgt gcgcccccca gcgcggcttc ggggcccctg     1020

cccttcttcc agttcaggcc gcggctggag agtgtggact ggcggcggct gagcgccatc     1080

gacgtggaca aggtggcggg ggctgtggac gtgctgacgc tgcaggagaa catcatgaac     1140

atcaccttct gcaagctgga agacgagaag tgcccacact gccagtcggg ggtggacccg     1200

gtgctgctga agctcatccg tctggcgcag ttcaccatcg agtacttgct gcactcacaa     1260

gagttcctca cctcgcagct gcacaccctg gaggagcggc tgcgcctgag ccactgcgac     1320

ggcgagcaga gcaagaagct gctcaccaag caggcggggg agatcaagac gctcaaggaa     1380

gagtgcaaac gccggaagaa gatgatctcc acccagcagc tgatgatcga ggccaaagcc     1440

aactattacc agtgccattt ttgtgacaag gcctttatga accaagcttt tctacaaagt     1500

cacattcaac gccgccacac tgaagaaaat tctcattttg agtatcagaa aaatgcacag     1560

attgagaagc tccggagtga gatcgtcgta ttgaaggaag agctgcagct caccaggtct     1620

gagctagagg ctgcacacca tgccagtgca gtcagattct ccaaggaata tgaaatgcag     1680

aaaacaaaag aggaagactt tttgaagtta tttgacaggt ggaaagaaga agaaaaggag     1740

aaactagttg atgaaatgga aaaagtcaag gagatgttta tgaaggaatt taaagaatta     1800

acttcgaaga attcagcatt agaatatcaa ctgtcagaaa tccagaagtc caatatgcag     1860

atcaagtcca acataggcac attaaaagat gcacacgagt ttaaagaaga ccgttctcca     1920

tatccccagg atttccataa tgtcatgcag cttcttgata gtcaggaaag caaatggaca     1980

gctcgagttc aagctattca tcaagaacac aagaaagaga agggtcggct cctgtcacat     2040

atagagaaac ttcgaacctc aatgatagat gatctaaatg caagcaatgt tttctataag     2100

aaaaggatag aagagctagg gcagagactc caggagcaga atgagctgat tataactcag     2160

agacagcaga ttaaagactt tacctgtaat ccattaaaca gtatcagtga acccaaagtg     2220

aatgccccag ccctgcacac tttggaaact aaatcaagtc tgccaatggt gcatgaacag     2280

gcattctcgt cgcacatact ggaaccaata gaagaacttt cagaggaaga aaaaggaagg     2340

gaaaatgaac agaaattaaa taacaacaaa atgcatttaa ggaaagcttt gaagagtaac     2400

tcctccctca ctaagggact aagaacaatg gtggagcaga acttgatgga gaaactggaa     2460

accttgggga ttaatgcaga tatacgtggc atttcaagtg atcagttgca tagagtacta     2520

aaaagtgtgg aatcagaaag acataagcaa gaaagagaaa tacctaactt tcatcaaatt     2580

cgagaattcc ttgaacatca agtcagctgt aaaattgagg agaaagcact actctcttca     2640

gatcagtgca gtgtttctca aatggatacc ctttcaactg gagaagtacc caaaatgata     2700

caacttcctt ccaaaaacag acaactgatt agacaaaaag ctgtttctac tgataggaca     2760

tctgttccaa aaattaagaa aaatgtcatg gaagatcctt ttcccagaaa gtcttcaact     2820

attacgaccc ctccttttag ttcagaggag gagcaggagg acgacgacct catccgggca     2880

tacgcatccc caggcccact tcctgtgccg ccaccacaaa acaagggcag cttcgggaag     2940

aacacagtga aaagtgacgc ggacgggacc gagggaagcg aaatcgagga cactgatgat     3000

tctcccaagc ccgcaggagt cgccgttaaa acacctactg aaaaagttga aaagatgttt     3060

ccacatcgca aaaatgtgaa caaaccagtc ggtggaacta atgtccctga gatgtttatc     3120

aaaaaagaag aattacaaga actaaagtgt gcggatgtgg aggatgaaga ctgggacata     3180

tcatccctag aggaagagat atctttggga aaaaaatctg ggaaagaaca gaaggaacct     3240

ccacctgcga aaaatgaacc acattttgct catgtgctaa atgcctgggg cgcatttaat     3300

cctaaggggc caaagggaga aggacttcaa gaaaatgaat caagcacatt aaaaagcagc     3360

ttagtaactg tgactgattg gagcgacact tcagatgtct aattccacat gtcagaagat     3420

tattccagaa gccagcagta tttcagtatc acagtgtttc agtaatttgc ctccatgatt     3480

ctagtgcttc tgccttaccg tgtttcccac agcaacacag agactgattc aaagaacaat     3540

ggtctcttta atggcaccca atacagtatt gaaaatcaga tcatcaacag tatttcgaag     3600

catgtaaagg tgtttaagac ttccgctgct gcttaaaaat aacatgtcat tgaagtcata     3660

aaaagttttt tcttcagaaa ggtactctag tgttaagtgt atttttttca actaattttt     3720

tagtgaattt tttttaaact tacagcatgt tttggtttga attactaaaa ctttaaaaaa     3780

tatttttctt atgtatgctg tcgtatcgta ggcgtttata ttataaaatt ctgttagtag     3840

tcttaaaatt gaattggtgg aaccactaat ccttaaaagt tagtctggtt atttttcata     3900

tagaagtaag tttaatccga gtgtggtggt gttcaccttt aatcccagct acttgggagg     3960

ctgaggtggg aggataactt gagcacagga gttcaagacc agcgtgggca atatagcaag     4020

actccacccc tccacacccc aaaaaagtaa gtttaggatt agaatatagc taggtccaat     4080

gttaaataca ttttcctgga gtacatttgt cacattcagc tttgagccac tgtaagcatg     4140

ttactattaa atggttggtt attttatata gcatattctt tatcttggat attttatgaa     4200

taaagtatag ttattttaag tgccaattaa tttatcagac taaatagaaa atatttgagc     4260

cattactgaa ttcacatatg tatgtttttt tttactattt aaaataccca acatgtatta     4320

tgaaatacct caaaagtaat ttagttacat tcttaaacaa tgacattgtc gaaagaaagt     4380

tcttataagc tgttttttgc atttttataa cttggttata ctatattctg tttccaagta     4440

accttttaac taaaagattt gttgggtttt agatctcttt tcatttgtca accttttcag     4500

taaagccctc tgttacatca ctgtgactgt ggctgtgtta ttagagatga attctgagtt     4560

aaatttgtac ttattagggg tcttacagag ggagaatctg gccttgattg ctatgccata     4620

tgacattctg tcctaatggt tagaacaaat ctttatctgt ttccacccac cctgggatcc     4680

tttttacttg tagcccattc ctgccctcta aaagaatcct tccaacttcc tataggggcc     4740

atttcatgca gatatactca ctttatatgt atgtttctaa aagctttagt gaaggctgaa     4800

tccaagtttc atgtagtagg acagagaaca gaaggccgaa tccaagtttc atgtggtagg     4860

acagagaacg gcaatctaca aaactacacc aagcctaaga tggcccatgt gccactttgt     4920

tcattcattt atttattcag cagatattta ttgaaccact tggtctggtt tggttttgaa     4980

cacgcactaa ttcatttaat tacaacaact ttgcgatgta gttattgtta taatcctcat     5040

cctaaaggtg tgagaaacag agttattaag taagttgcca gaagccatac aagtacaaag     5100

tgtcaagggg agactttaag ccaggtctct attccatgtt ttgtgtctgc catgttttca     5160

ttcctgagca gaagagcttg gggaaatgaa cttttgctaa gtaaacccag tatttaaatt     5220

aagtcactat atctgtgtct tttaagagcc cctcctttag cttacatggt tagttgtatc     5280

tttttttttt tttttttttg agacagagtc tcactatgtt gcccaggctt gagcgcagtg     5340

gcaccatctc ggctcactac aacctccgcc tcccagattc aagcgatttt cctgcctcag     5400

cctcccaagt agctgggatt acaggtgccc accaccatgc ctggcttaat tttttgtatt     5460

tttagtagag atgaggtttc accatgttgg ccagactggt ctcgaactcc tgacctcaaa     5520

tgatccgctg tcttgtcctc ccaaagtgct gggattatag gcgtgagcca tcgcgccctg     5580

ctgcatttca tttttttgta taaaatttgg tttgttcgtt tttgagggga accattcctt     5640

tatgttgccc cttactgatg cccaactaat gtgtttctgg ttactaacag accttcatcc     5700

cccaccctcc ctaaattctt cggtgtaatc taagcgttat ctgcaccact tctgaataat     5760

aaatgtgttt gaaatgcaca cctacacaac cctgtcccac actggcctgt aggacctaat     5820

ctaccttcat gtctttcagt tgatttgtat ttctgcaaaa gatatttcaa ggattatcaa     5880

ggtatggaat tttttttatt ttttatcttt taacaaactt gttcatttcc ttttctttcc     5940

attgagcacc tctgaacaat gtgattcttt tttttaagtc tttcacactt caggaaaata     6000

ctacattcac ccacgttgtg attcatatcg gacagtttct tactcaaaga taacacaaat     6060

accaattctt attcatactt tgaaactata ttttacccta gactgccttg gttcaaaggc     6120

ctagtttcga cattactgtg gcaaattatt taagctctct gttttcattt ctttttctgt     6180

aaatgcagga tgaaaacaat atgtatctcc taggatggct gtgaggagtg agtgagacag     6240

gacatgaaag gtgtgtatga actgtgataa ctgttgccct tgtgggcatg ttatataggg     6300

ctggctctag gaagaagcct gtgtcttttt tcagaaatcc ctggagcaac ttaaatgtct     6360

ttagaaatga caagtctctc agttatccag ttagccgtaa acaggttctg gaagacacac     6420

ctagatagaa ctcggcccgt cagttctgag tgaggcacgt accacttggg cttgggatgt     6480

ccttaaccca tttatgcctg aggttgcaat tttttgaatt tttccaatca caccttggcg     6540

atgaccttga gcagtaggat ataaataact cccacatgct tagtgttcca ataatggaac     6600

actaggcata aacaggtttt aattggctcc tcagtcaacc atgaccaata tctctatctc     6660

agcttctgct gatgccctag ctcagggctc tgcattccgt gccagggacg cctcagcccc     6720

ttaacatgga tgtgccacat gacaggcaat aatatattgg ccccattagc ccttcctgga     6780

gcagtcataa tgaattacag tcatgacagg cacatgtaag aaaccaaaat ttgctaaata     6840

tgtacatgag tcttcatcac agcatcgttt atgaaaacaa ctaaatattc actaatggtg     6900

ccagtggaat aaatcagaga acatcccctg ctacgtaact ctctgcatac atcaaagaga     6960

atggtgtggc tttgcttttt caacaatcta ctgagtggcc atgggcatgt ggatatggcc     7020

atgaatgagc aagatcctct ctgatcctgt agaagttaag ttctaccaga taacttgctg     7080

cttcaacaaa aagatttacc tttttaaata aatgttgtag aatacttaaa aaaaacaaac     7140

tagaatttgc ctgtgtgcag ccagtaacat gtctatttaa cctggacacc ttttgaggaa     7200

tattctcaga ttgcccccat gctgtttata agacattgtt ccttatacac ctgtttatga     7260

atgaaaagaa acataaggag tgggtacaaa gacttctatc tatgaatgat taaaaaggct     7320

agagtacgaa tacttcttga acctttggta ctaaatgctt ttcatgttct atataaatgt     7380

agaaaacatt ttacaaatcc tgtaaataaa ctgtttattt tttatagaaa gccaaaaaaa     7440

a                                                                     7441


<210>  2109
<211>  6784
<212>  DNA
<213>  homo sapiens

<400>  2109
ggcgccgcct ccacccgctc cccgctcggt cccgctcgct cgcccaggcc gggctgccct       60

ttcgcgtgtc cgcgctctct tccctccgcc gccgcctcct ccattttgcg agctcgtgtc      120

tgtgacggga gcccgagtca ccgcctgccc gtcggggacg gattctgtgg gtggaaggag      180

acgccgcagc cggagcggcc gaagcagctg ggaccgggac ggggcacgcg cgcccggaac      240

ctcgacccgc ggagcccggc gcggggcgga gggctggctt gtcagctggg caatgggaga      300

ctttcttaaa taggggctct ccccccaccc atggagaaag gggcggctgt ttacttcctt      360

tttttagaaa aaaaaaatat atttccctcc tgctccttct gcgttcacaa gctaagttgt      420

ttatctcggc tgcggcggga actgcggacg gtggcgggcg agcggctcct ctgccagagt      480

tgatattcac tgatggactc caaagaatca ttaactcctg gtagagaaga aaaccccagc      540

agtgtgcttg ctcaggagag gggagatgtg atggacttct ataaaaccct aagaggagga      600

gctactgtga aggtttctgc gtcttcaccc tcactggctg tcgcttctca atcagactcc      660

aagcagcgaa gacttttggt tgattttcca aaaggctcag taagcaatgc gcagcagcca      720

gatctgtcca aagcagtttc actctcaatg ggactgtata tgggagagac agaaacaaaa      780

gtgatgggaa atgacctggg attcccacag cagggccaaa tcagcctttc ctcgggggaa      840

acagacttaa agcttttgga agaaagcatt gcaaacctca ataggtcgac cagtgttcca      900

gagaacccca agagttcagc atccactgct gtgtctgctg cccccacaga gaaggagttt      960

ccaaaaactc actctgatgt atcttcagaa cagcaacatt tgaagggcca gactggcacc     1020

aacggtggca atgtgaaatt gtataccaca gaccaaagca cctttgacat tttgcaggat     1080

ttggagtttt cttctgggtc cccaggtaaa gagacgaatg agagtccttg gagatcagac     1140

ctgttgatag atgaaaactg tttgctttct cctctggcgg gagaagacga ttcattcctt     1200

ttggaaggaa actcgaatga ggactgcaag cctctcattt taccggacac taaacccaaa     1260

attaaggata atggagatct ggttttgtca agccccagta atgtaacact gccccaagtg     1320

aaaacagaaa aagaagattt catcgaactc tgcacccctg gggtaattaa gcaagagaaa     1380

ctgggcacag tttactgtca ggcaagcttt cctggagcaa atataattgg taataaaatg     1440

tctgccattt ctgttcatgg tgtgagtacc tctggaggac agatgtacca ctatgacatg     1500

aatacagcat ccctttctca acagcaggat cagaagccta tttttaatgt cattccacca     1560

attcccgttg gttccgaaaa ttggaatagg tgccaaggat ctggagatga caacttgact     1620

tctctgggga ctctgaactt ccctggtcga acagtttttt ctaatggcta ttcaagcccc     1680

agcatgagac cagatgtaag ctctcctcca tccagctcct caacagcaac aacaggacca     1740

cctcccaaac tctgcctggt gtgctctgat gaagcttcag gatgtcatta tggagtctta     1800

acttgtggaa gctgtaaagt tttcttcaaa agagcagtgg aaggacagca caattaccta     1860

tgtgctggaa ggaatgattg catcatcgat aaaattcgaa gaaaaaactg cccagcatgc     1920

cgctatcgaa aatgtcttca ggctggaatg aacctggaag ctcgaaaaac aaagaaaaaa     1980

ataaaaggaa ttcagcaggc cactacagga gtctcacaag aaacctctga aaatcctggt     2040

aacaaaacaa tagttcctgc aacgttacca caactcaccc ctaccctggt gtcactgttg     2100

gaggttattg aacctgaagt gttatatgca ggatatgata gctctgttcc agactcaact     2160

tggaggatca tgactacgct caacatgtta ggagggcggc aagtgattgc agcagtgaaa     2220

tgggcaaagg caataccagg tttcaggaac ttacacctgg atgaccaaat gaccctactg     2280

cagtactcct ggatgtttct tatggcattt gctctggggt ggagatcata tagacaatca     2340

agtgcaaacc tgctgtgttt tgctcctgat ctgattatta atgagcagag aatgactcta     2400

ccctgcatgt acgaccaatg taaacacatg ctgtatgttt cctctgagtt acacaggctt     2460

caggtatctt atgaagagta tctctgtatg aaaaccttac tgcttctctc ttcagttcct     2520

aaggacggtc tgaagagcca agagctattt gatgaaatta gaatgaccta catcaaagag     2580

ctaggaaaag ccattgtcaa gagggaagga aactccagcc agaactggca gcggttttat     2640

caactgacaa aactcttgga ttctatgcat gaagtggttg aaaatctcct taactattgc     2700

ttccaaacat ttttggataa gaccatgagt attgaattcc ccgagatgtt agctgaaatc     2760

atcaccaatc agataccaaa atattcaaat ggaaatatca aaaaacttct gtttcatcaa     2820

aagtgactgc cttaataaga atggttgcct taaagaaagt cgaattaata gcttttattg     2880

tataaactat cagtttgtcc tgtagaggtt ttgttgtttt attttttatt gttttcatct     2940

gttgttttgt tttaaatacg cactacatgt ggtttataga gggccaagac ttggcaacag     3000

aagcagttga gtcgtcatca cttttcagtg atgggagagt agatggtgaa atttattagt     3060

taatatatcc cagaaattag aaaccttaat atgtggacgt aatctccaca gtcaaagaag     3120

gatggcacct aaaccaccag tgcccaaagt ctgtgtgatg aactttctct tcatactttt     3180

tttcacagtt ggctggatga aattttctag actttctgtt ggtgtatccc ccccctgtat     3240

agttaggata gcatttttga tttatgcatg gaaacctgaa aaaaagttta caagtgtata     3300

tcagaaaagg gaagttgtgc cttttatagc tattactgtc tggttttaac aatttccttt     3360

atatttagtg aactacgctt gctcattttt tcttacataa ttttttattc aagttattgt     3420

acagctgttt aagatgggca gctagttcgt agctttccca aataaactct aaacattaat     3480

caatcatctg tgtgaaaatg ggttggtgct tctaacctga tggcacttag ctatcagaag     3540

accacaaaaa ttgactcaaa tctccagtat tcttgtcaaa aaaaaaaaaa aaaaagctca     3600

tattttgtat atatctgctt cagtggagaa ttatataggt tgtgcaaatt aacagtccta     3660

actggtatag agcacctagt ccagtgacct gctgggtaaa ctgtggatga tggttgcaaa     3720

agactaattt aaaaaataac taccaagagg ccctgtctgt acctaacgcc ctatttttgc     3780

aatggctata tggcaagaaa gctggtaaac tatttgtctt tcaggacctt ttgaagtagt     3840

ttgtataact tcttaaaagt tgtgattcca gataaccagc tgtaacacag ctgagagact     3900

tttaatcaga caaagtaatt cctctcacta aactttaccc aaaaactaaa tctctaatat     3960

ggcaaaaatg gctagacacc cattttcaca ttcccatctg tcaccaattg gttaatcttt     4020

cctgatggta caggaaagct cagctactga tttttgtgat ttagaactgt atgtcagaca     4080

tccatgtttg taaaactaca catccctaat gtgtgccata gagtttaaca caagtcctgt     4140

gaatttcttc actgttgaaa attattttaa acaaaataga agctgtagta gccctttctg     4200

tgtgcacctt accaactttc tgtaaactca aaacttaaca tatttactaa gccacaagaa     4260

atttgatttc tattcaaggt ggccaaatta tttgtgtaat agaaaactga aaatctaata     4320

ttaaaaatat ggaacttcta atatattttt atatttagtt atagtttcag atatatatca     4380

tattggtatt cactaatctg ggaagggaag ggctactgca gctttacatg caatttatta     4440

aaatgattgt aaaatagctt gtatagtgta aaataagaat gatttttaga tgagattgtt     4500

ttatcatgac atgttatata ttttttgtag gggtcaaaga aatgctgatg gataacctat     4560

atgatttata gtttgtacat gcattcatac aggcagcgat ggtctcagaa accaaacagt     4620

ttgctctagg ggaagaggga gatggagact ggtcctgtgt gcagtgaagg ttgctgaggc     4680

tctgacccag tgagattaca gaggaagtta tcctctgcct cccattctga ccacccttct     4740

cattccaaca gtgagtctgt cagcgcaggt ttagtttact caatctcccc ttgcactaaa     4800

gtatgtaaag tatgtaaaca ggagacagga aggtggtgct tacatcctta aaggcaccat     4860

ctaatagcgg gttactttca catacagccc tcccccagca gttgaatgac aacagaagct     4920

tcagaagttt ggcaatagtt tgcatagagg taccagcaat atgtaaatag tgcagaatct     4980

cataggttgc caataataca ctaattcctt tctatcctac aacaagagtt tatttccaaa     5040

taaaatgagg acatgttttt gttttctttg aatgcttttt gaatgttatt tgttattttc     5100

agtattttgg agaaattatt taataaaaaa acaatcattt gctttttgaa tgctctctaa     5160

aagggaatgt aatattttaa gatggtgtgt aacccggctg gataaatttt tggtgcctaa     5220

gaaaactgct tgaatattct tatcaatgac agtgttaagt ttcaaaaaga gcttctaaaa     5280

cgtagattat cattccttta tagaatgtta tgtggttaaa accagaaagc acatctcaca     5340

cattaatctg attttcatcc caacaatctt ggcgctcaaa aaatagaact caatgagaaa     5400

aagaagatta tgtgcacttc gttgtcaata ataagtcaac tgatgctcat cgacaactat     5460

aggaggcttt tcattaaatg ggaaaagaag ctgtgccctt ttaggatacg tgggggaaaa     5520

gaaagtcatc ttaattatgt ttaattgtgg atttaagtgc tatatggtgg tgctgtttga     5580

aagcagattt atttcctatg tatgtgttat ctggccatcc caacccaaac tgttgaagtt     5640

tgtagtaact tcagtgagag ttggttactc acaacaaatc ctgaaaagta tttttagtgt     5700

ttgtaggtat tctgtgggat actatacaag cagaactgag gcacttagga cataacactt     5760

ttggggtata tatatccaaa tgcctaaaac tatgggagga aaccttggcc accccaaaag     5820

gaaaactaac atgatttgtg tctatgaagt gctggataat tagcatggga tgagctctgg     5880

gcatgccatg aaggaaagcc acgctccctt cagaattcag aggcagggag caattccagt     5940

ttcacctaag tctcataatt ttagttccct tttaaaaacc ctgaaaacta catcaccatg     6000

gaatgaaaaa tattgttata caatacattg atctgtcaaa cttccagaac catggtagcc     6060

ttcagtgaga tttccatctt ggctggtcac tccctgactg tagctgtagg tgaatgtgtt     6120

tttgtgtgtg tgtgtctggt tttagtgtca gaagggaaat aaaagtgtaa ggaggacact     6180

ttaaaccctt tgggtggagt ttcgtaattt cccagactat tttcaagcaa cctggtccac     6240

ccaggattag tgaccaggtt ttcaggaaag gatttgcttc tctctagaaa atgtctgaaa     6300

ggattttatt ttctgatgaa aggctgtatg aaaataccct cctcaaataa cttgcttaac     6360

tacatataga ttcaagtgtg tcaatattct attttgtata ttaaatgcta tataatgggg     6420

acaaatctat attatactgt gtatggcatt attaagaagc tttttcatta ttttttatca     6480

cagtaatttt aaaatgtgta aaaattaaaa ccagtgactc ctgtttaaaa ataaaagttg     6540

tagtttttta ttcatgctga ataataatct gtagttaaaa aaaaagtgtc tttttaccta     6600

cgcagtgaaa tgtcagactg taaaaccttg tgtggaaatg tttaactttt attttttcat     6660

ttaaatttgc tgttctggta ttaccaaacc acacatttgt accgaattgg cagtaaatgt     6720

tagccattta cagcaatgcc aaatatggag aaacatcata ataaaaaaat ctgctttttc     6780

atta                                                                  6784


<210>  2110
<211>  5453
<212>  DNA
<213>  homo sapiens

<400>  2110
tggccagacc ctgccgcctg agagagagca cagcctggtg ggttctgggg tctacggcct       60

aggggccggg gaagtttgcg ccgccgcgac cagtgctgcg atcccgagcc gggctccagc      120

cccgaggacc aggggtcggg cgggcctgcc tacggaaccc cgcgggccag cagcagtcgt      180

ctcgcgtcct cctgcttgga aaagtgttta agcttctaaa atgtcatcta tcaagcacct      240

ggtttatgca gttattcgtt tcttacggga acaaagtcag atggacactt acacctcgga      300

tgaacaagaa agtttggaag ttgcaattca gtgcttggag acagttttta agatcagccc      360

agaagataca cacctagcag tttcacagcc tttgacagaa atgtttacca gttccttctg      420

taagaatgac gttctgcccc tttcaaactc agtgcctgaa gatgtgggaa aagctgacca      480

attaaaagat gaaggcaata accacatgaa agaagaaaat tatgctgctg cagtggattg      540

ttacacacag gcaatagaat tggatcccaa taatgcagtt tactattgca acagggctgc      600

tgctcagagc aaattaggtc actacacaga tgcgataaag gattgtgaaa aagcaatagc      660

aattgattca aagtacagca aggcctatgg gagaatgggg ctggccctca ctgccttgaa      720

taaatttgaa gaagcagtta caagttatca aaaggcatta gatcttgacc ctgaaaatga      780

ttcctataag tcaaatctga aaatagcaga acagaagtta agagaggtat ccagtcctac      840

aggaactgga ctgagctttg acatggctag cttgataaat aatccagcct tcattagtat      900

ggcggcaagt ttaatgcaga accctcaagt tcaacagcta atgtcaggaa tgatgacaaa      960

tgccattggg ggacctgctg ctggagttgg gggcctaact gacctgtcaa gcctcatcca     1020

agcgggacag cagtttgctc agcagataca gcaacaaaat cctgaactta tagagcaact     1080

gagaaatcac atccggagca gatcattcag cagcagcgct gaagagcatt cctgatttaa     1140

ccaggggctc aagcccaaga tacaaatggt ttatggctat gaatgaagta tttgttgtag     1200

atagtacccc ctccctcctt caaaaaacca aacaccatat ctgatgtgtg aaaataatgg     1260

aggaaaacct cttgtgtata ttcttaaaga ataaatctgt ttagacaata ggtttatcac     1320

aaacaaactc aaaacataac atgactcctt ttgaaatgat cactagccat gttacgtgcc     1380

aatatagcac tgggataagg ttccattttc aaacttctat catatttgta tattagactt     1440

aatagcaaag catatttatt gaactctagt agggctattt gttggtaagc tctttagctc     1500

caatttccct taagcaaagt tttttgagaa gggaaatgac ccaaaggaaa ggtttcctat     1560

gctggttgag aagaagtgta cttgccactg agcagtatgt caggaaagaa ggaatattat     1620

ctaggtttag ctttgataag tgctattagt aatgaatata taacatggga accaatgtta     1680

tctttaatgt tgcttgttct ggtgaacaga gaatcttaag agctgttaga aagtagcact     1740

tgatgcaagg gatgttttga aaagaaaaaa ttggtaatgc gaatgtatag aaagtaaagg     1800

taggatgctc aggttttctg catagttctt aactaatctt gtctgcagtt tggtattgat     1860

aatattagca tggccactta tgctaaatac acaataagat acatttagaa atccttaatg     1920

tactggttag gtcagtggta caactgtttg acttaattat cacaatttcc ccaatggtaa     1980

ccttaccttg gaaactatca aatataaata tactttaact aagccagtga cctggtccta     2040

agttaaggat tttctaaatg gtatttaatt gtgtgcccat aaacactgat tttttttaaa     2100

aagaaaactt agtaattatt tgatggataa caaaaagcat ctatcactaa cattgcttgt     2160

tcatgtaatc ttctgtgata atttggcttg gcatgccagt cttataatta acataattta     2220

aatttgatgc aatttaaata taacaggaga cttaaaatat tttattataa attagatgcc     2280

atattagtta gtggagaaaa ggggcattag gtattaattg catgggtcta actacattga     2340

tgatgagagt ttaattccaa ctagagtata ttttttgttt attaataatg aaattggtgc     2400

tgacatgtaa tgacttcaca agttttacga gggaaaactg aaaaaggaag taatataaat     2460

tttgtggggt ttttttgaga tggagtctta ctcttttgcc aggctagagt ggtgttgcaa     2520

tgtcagctca ctgcaacctc cacctcctgg attcaagtga ttctcgagcc ttaagctccc     2580

aagtagctgg gattacgggc gcccaccacc acgcccagct aatttttttt ttttttttct     2640

tgagatggag tctctctctg tcgccaggct ggagtgcagt ggcgcaatcg cggctcactg     2700

caacctctgc ctcccgggtt caagtgattc tcctgcctca gcctcctgag tagctgggat     2760

tacaggcacg tgtcaccatg cccagctaat ttttgtattt ttagtagaga cggggtttca     2820

ccatgtttgc caggattgtc tcaatctctt gacctcgtga tccgcctgcc ttggcctccc     2880

aaatgctggg attacaggcg tgagccaccg tgcctggccg ctaatttttg tttttaatgg     2940

agagagttcc accgtatcgg ccaggctggt ctcgaactcc tgacctcaag tgatctgccc     3000

atcttggccc ctcaaagtgc tgggattaga ggtgtgagcc actgtgcctg gccaggaagt     3060

aatatacaat taaatgagta ataatgcaga tgattaggcc ttatagaacc cttatcaaaa     3120

gactaattgg ccgggcgctg tggctcatgc ctgtaatccc agcactttgg gaggccaagg     3180

caggggggat cacctgaggt caggagtttg agaccagcct ggccaacatg gtgaaaccca     3240

cctctactga aaatacaaaa attagcctgg cttggtggcg ggcacccgta gtcccagcta     3300

cttgggaggc tgaagcatga gaattgctcg aacctgagag gcagaggttg cagtgagcca     3360

agattgcgcc actgcactcc agcctgggtg acagagcaag actccatttc aaaaaaaaaa     3420

aaaaaaagaa aaagagacta agagactaat tattttgtat cttgaagttt aaaatccaac     3480

ttttctcttt ctcctttgtg acattagaac agtagttcta taacttcatt gtaagaatca     3540

cctggataat tcattaaaga tgcagattca gggccacgtg ttcaattctg atacagtagg     3600

tcctgtaata aggcctagga atggccattt ttaaacagta cactaggtgg ttttgataca     3660

gatccaagga ctctaattta gaggaacact aggttagagg tttctcagac ctgcaaacac     3720

ctaagcacct gggccaaaca aagctacaac gaagatctgt atgaagatat atagttctgc     3780

agaatttaaa aagagcacaa tttaagtctt cggccctcag aagttaaatt catattccat     3840

ctaagccaac tttgattttc attaagttag aatgaactcc tagtattcca gtattacaca     3900

gaacgaagta ctactactaa cacatagaag tcattactgt gatataaaaa gcaaaataga     3960

tccttaatta aaaattagtc actcatattc agtgttgaat aagaagttaa agtttctagc     4020

ataactatct tgagtgcatt aaaaatgctt ttagagcaat aagataagct tctagctgac     4080

tgcctagaaa aacagaagat acaaattcag tgtcagaaat gaaagggaat acactacaga     4140

cactatagtt attaaaaggc taactagaaa acaccatgac caactcaagg attgtatatt     4200

taacaactta gatgaaacag attccctata ggatacaaac tagaaagctc actgtagaaa     4260

cagataacct aaacagaacc atatttatta aggaaattga gtttgtggtt aagttaaaaa     4320

ccttccagta aagaaaacta caggcccaga taacttccgt gatgaatttt accaaacact     4380

taagggagaa ataatatcaa ttctaaacaa tctcttccag gaaacagaag aggaggaaat     4440

acttcccaac tcattttatt tgaccagtat tacccagaca aagatactat aagaaaaaaa     4500

actttaaaac aatgtcttca tgtgctaaca tctgtagtta aattagccat tctttttaca     4560

tgaaataatg ggaattggta tatttcttcc atttcatttt tctatttctt tgctaatata     4620

ccacctgtaa caaattcaat ctagatgcta tctgtccact tgcctacatt tccattctat     4680

tcaagccatt tttgctcttc aagtaccttg atcactttgg aatcatagca ttgcaagcta     4740

tttcaaaaaa agttgcgtgg ttggattgtg ctagctactt ttaaatttat aaaaaatgcc     4800

ccatatattt tcttgcttgt ctgggaaata tagttgctat ctaactagaa aaataagagg     4860

gcattattaa agtaactctt taagcatcgt actaaatgtt tgacttccat taaccatatt     4920

tcttgtagta gctgtagcta ttatgatact gtgtaaaaca gaacaggttc tatatatgca     4980

aatgacattt tcatttaatg taccaaattg tgtatctaac ttttataata taggttaaac     5040

agatcctttc taagatggca ttatttaatc tttacttaaa actatgaaaa atatgtgtaa     5100

gttattgttt ataaacagaa gagactataa ttaaaatata gagcagattc caagtgacca     5160

tcattttact ttttagattt aaaacagaat gaaacagaag atttagtcat aagaagatgc     5220

ttgaaaaaca atccaagtat ccaatgcagt ggctataaaa tattatttca tcatttaatc     5280

ttaatcattt tgaaacaaag acagacttca attttacact gcttgcactt tattttgtac     5340

agacatttca ttaattatta ctcaattttg aggtgcaaac cttctgaata tagctttcat     5400

tttggaccaa acaatttgtt atggcaataa ataatgatgc attgaaaaac caa            5453


<210>  2111
<211>  1102
<212>  DNA
<213>  homo sapiens

<400>  2111
actggtgacg tagatctcat gtgaccagga gtcgacgtgt gcagaagtcc tggtaatctg       60

gtccttgttc ccgtctggat accagcttcc ttcagcagcg caggcggtgg tccctgaggc      120

ccgtggaagg agtcaaactt gcgggaattt tgcagtttat ctgcagggct gttgtttcca      180

gcaagaccca aagctagaaa aggaggagga agaaactgac ccgatcagtg ccagaagtca      240

ttgtattcaa agaagaataa gcaagaaaga aaagaaggaa ggaagagagg tagacagata      300

caagatgaaa tcctgtcaaa aaatggaagg aaaaccagaa aatgagagtg aaccaaagca      360

tgaggaagag ccaaagcctg aggaaaagcc agaagaggag gagaagctag aggaggaggc      420

caaagcaaaa ggaactttta gagaaaggct gattcaatct ctccaggagt ttaaagaaga      480

tatacacaac aggcatttaa gcaatgaaga tatgtttaga gaagtggatg aaatagatga      540

gataaggaga gtcagaaaca aacttatagt gatgcgttgg aaggttaatc gaaaccatcc      600

ttacccctat ttaatgtagt ttaccttgat ttttatctga tattaacaat accatatagc      660

ttgcttttta ttagcatttc ctgatattcc tttgtccata tttctactta taacctgttg      720

ctattaatgg ttttagatgt atctcttgtt atctgcatct cattgtttat tgtattttga      780

accaatctac aagtctctgt cttttaataa aagaacttta cacatttgta aaaaagaggt      840

tcttggtaag atataaaatg gaaaaaggct aagtaatatg tgaatatcat atttttgaaa      900

ggtaaaaagt acatttgtat attacatata tggacataac ttgtgaagga tgaaagaaag      960

tacagcctct cggtggtggg attatgaatg atttttctcc ttttgcttgt ttgtattttc     1020

tatattccta aaattaacac acattattat tgctagaata ataaaagttt tataaaaaag     1080

aagcaacaaa aaaaaaaaaa aa                                              1102


<210>  2112
<211>  3976
<212>  DNA
<213>  homo sapiens

<400>  2112
ctgggtcctg tgtgtgccac aggggtgggg tgtccagcga gcggtctcct cctcctgcta       60

gtgctgctgc ggcgtcccgc ggcctccccg agtcgggcgg gaggggagag cgggtgtgga      120

tttgtcttga cggtaattgt tgcgtttcca cgtctcggag gcctgcgcgc tgggttgctc      180

cttcttcggg agcgagctgt tctcagcgat cccactccca gccggggctc cccacacaca      240

ctgggctgcg tgcgtgtgga gtgggacccg cgcacacgcg tgtctctgga cagctacggc      300

gccgaaagaa ctaaaattcc agatggcaaa ctcaatgaat ggcagaaacc ctggtggtcg      360

aggaggaaat ccccgaaaag gtcgaatttt gggtattatt gatgctattc aggatgcagt      420

tggaccccct aagcaagctg ccgcagatcg caggaccgtg gagaagactt ggaagctcat      480

ggacaaagtg gtaagactgt gccaaaatcc caaacttcag ttgaaaaata gcccaccata      540

tatacttgat attttgcctg atacatatca gcatttacga cttatattga gtaaatatga      600

tgacaaccag aaacttgccc aactcagtga gaatgagtac tttaaaatct acattgatag      660

ccttatgaaa aagtcaaaac gggcaataag actctttaaa gaaggcaagg agagaatgta      720

tgaagaacag tcacaggaca gacgaaatct cacaaaactg tcccttatct tcagtcacat      780

gctggcagaa atcaaagcaa tctttcccaa tggtcaattc cagggagata actttcgtat      840

cacaaaagca gatgctgctg aattctggag aaagtttttt ggagacaaaa ctatcgtacc      900

atggaaagta ttcagacagt gccttcatga ggtccaccag attagctctg gcctggaagc      960

aatggctcta aaatcaacaa ttgatttaac ttgcaatgat tacatttcag tttttgaatt     1020

tgatattttt accaggctgt ttcagccttg gggctctatt ttgcggaatt ggaatttctt     1080

agctgtgaca catccaggtt acatggcatt tctcacatat gatgaagtta aagcacgact     1140

acagaaatat agcaccaaac ccggaagcta tattttccgg ttaagttgca ctcgattggg     1200

acagtgggcc attggctatg tgactgggga tgggaatatc ttacagacca tacctcataa     1260

caagccctta tttcaagccc tgattgatgg cagcagggaa ggattttatc tttatcctga     1320

tgggaggagt tataatcctg atttaactgg attatgtgaa cctacacctc atgaccatat     1380

aaaagttaca caggaacaat atgaattata ttgtgaaatg ggctccactt ttcagctctg     1440

taagatttgt gcagagaatg acaaagatgt caagattgag ccttgtgggc atttgatgtg     1500

cacctcttgc cttacggcat ggcaggagtc ggatggtcag ggctgccctt tctgtcgttg     1560

tgaaataaaa ggaactgagc ccataatcgt ggaccccttt gatccaagag atgaaggctc     1620

caggtgttgc agcatcattg acccctttgg catgccgatg ctagacttgg acgacgatga     1680

tgatcgtgag gagtccttga tgatgaatcg gttggcaaac gtccgaaagt gcactgacag     1740

gcagaactca ccagtcacat caccaggatc ctctcccctt gcccagagaa gaaagccaca     1800

gcctgaccca ctccagatcc cacatctaag cctgccaccc gtgcctcctc gcctggatct     1860

aattcagaaa ggcatagtta gatctccctg tggcagccca acgggttcac caaagtcttc     1920

tccttgcatg gtgagaaaac aagataaacc actcccagca ccacctcctc ccttaagaga     1980

tcctcctcca ccgccacctg aaagacctcc accaatccca ccagacaata gactgagtag     2040

acacatccat catgtggaaa gcgtgccttc cagagacccg ccaatgcctc ttgaagcatg     2100

gtgccctcgg gatgtgtttg ggactaatca gcttgtggga tgtcgactcc taggggaggg     2160

ctctccaaaa cctggaatca cagcgagttc aaatgtcaat ggaaggcaca gtagagtggg     2220

ctctgaccca gtgcttatgc ggaaacacag acgccatgat ttgcctttag aaggagctaa     2280

ggtcttttcc aatggtcacc ttggaagtga agaatatgat gttcctcccc ggctttctcc     2340

tcctcctcca gttaccaccc tcctccctag cataaagtgt actggtccgt tagcaaattc     2400

tctttcagag aaaacaagag acccagtaga ggaagatgat gatgaataca agattccttc     2460

atcccaccct gtttccctga attcacaacc atctcattgt cataatgtaa aacctcctgt     2520

tcggtcttgt gataatggtc actgtatgct gaatggaaca catggtccat cttcagagaa     2580

gaaatcaaac atccctgact taagcatata tttaaaggga gatgtttttg attcagcctc     2640

tgatcccgtg ccattaccac ctgccaggcc tccaactcgg gacaatccaa agcatggttc     2700

ttcactcaac aggacgccct ctgattatga tcttctcatc cctccattag gtgaagatgc     2760

ttttgatgcc ctccctccat ctctcccacc tcccccacct cctgcaaggc atagtctcat     2820

tgaacattca aaacctcctg gctccagtag ccggccatcc tcaggacagg atctttttct     2880

tcttccttca gatccctttg ttgatctagc aagtggccaa gttcctttgc ctcctgctag     2940

aaggttacca ggtgaaaatg tcaaaactaa cagaacatca caggactatg atcagcttcc     3000

ttcatgttca gatggttcac aggcaccagc cagaccccct aaaccacgac cgcgcaggac     3060

tgcaccagaa attcaccaca gaaaacccca tgggcctgag gcggcattgg aaaatgtcga     3120

tgcaaaaatt gcaaaactca tgggagaggg ttatgccttt gaagaggtga agagagcctt     3180

agagatagcc cagaataatg tcgaagttgc ccggagcatc ctccgagaat ttgccttccc     3240

tcctccagta tccccacgtc taaatctata gcagccagaa ctgtagacac caaaatggaa     3300

agcaatcgat gtattccaag agtgtggaaa taaagagaac tgagatggaa ttcaagagag     3360

aagtgtctcc tcctcgtgta gcagcttgag aagaggcttg ggagtgcagc ttctcaaagg     3420

agaccgatgc ttgctcagga tgtcgacagc tgtggcttcc ttgtttttgc tagccatatt     3480

tttaaatcag ggttgaactg acaaaaataa tttaaagacg tttacttccc ttgaactttg     3540

aacctgtgaa atgctttacc ttgtttacag tttggcaaag ttgcagtttg ttcttgtttt     3600

tagtttagtt ttgttttggt gttttgatac ctgtactgtg ttcttcacag accctttgta     3660

gcgtggtcag gtctgctgta acatttccca ccaactctct tgctgtccac atcaacagct     3720

aaatcattta ttcatatgga tctctaccat ccccatgcct tgcccaggtc cagttccatt     3780

tctctcattc acaagatgct ttgaaggttc tgattttcaa ctgatcaaac taatgcaaaa     3840

aaaaaaaagt atgtattctt cactactgag tttcttcttt ggaaaccatc actattgaga     3900

gatgggaaaa acctgaatgt ataaagcatt tatttgtcaa taaactgcct tttgtaaggg     3960

gttttcacat aacata                                                     3976


<210>  2113
<211>  5825
<212>  DNA
<213>  homo sapiens

<400>  2113
atcgcctggg taggtttcca gggaaggcag cgagcaggat cccctactct gcgggcggcg       60

cgaggcgtct ggctcttcgc ggcggcggcg aggggaaagg gagcgcgggg gctgggtgga      120

atcgaggagt gaggaaaaag ggaaggggcg ggggagaggg accagggaag gcgtcggggg      180

gaatctcgcg agggttggag ttttggcgag agtttgtgga agatggcgcc tgttgtgaca      240

gggaaatttg gtgagcggcc tccacctaaa cgacttacta gggaagctat gcgaaattat      300

ttaaaagagc gaggggatca aacagtactt attcttcatg caaaagttgc acagaagtca      360

tatggaaatg aaaaaaggtt tttttgccca cctccttgtg tatatcttat gggcagtgga      420

tggaagaaaa aaaaagaaca aatggaacgc gatggttgtt ctgaacaaga gtctcaaccg      480

tgtgcattta ttgggatagg aaatagtgac caagaaatgc agcagctaaa cttggaagga      540

aagaactatt gcacagccaa aacattgtat atatctgact cagacaagcg aaagcacttc      600

atgttgtctg taaagatgtt ctatggcaac agtgatgaca ttggtgtgtt cctcagcaag      660

cggataaaag tcatctccaa accttccaaa aagaagcagt cattgaaaaa tgctgactta      720

tgcattgcct caggaacaaa ggtggctctg tttaatcgac tacgatccca gacagttagt      780

accagatact tgcatgtaga aggaggtaat tttcatgcca gttcacagca gtggggagcc      840

ttttttattc atctcttgga tgatgatgaa tcagaaggag aagaattcac agtccgagat      900

ggctacatcc attatggaca aacagtcaaa cttgtgtgct cagttactgg catggcactc      960

ccaagattga taattaggaa agttgataag cagaccgcat tattggatgc agatgatcct     1020

gtgtcacaac tccataaatg tgcattttac cttaaggata cagaaagaat gtatttgtgc     1080

ctttctcaag aaagaataat tcaatttcag gccactccat gtccaaaaga accaaataaa     1140

gagatgataa atgatggcgc ttcctggaca atcattagca cagataaggc agagtataca     1200

ttttatgagg gaatgggccc tgtccttgcc ccagtcactc ctgtgcctgt ggtagagagc     1260

cttcagttga atggcggtgg ggacgtagca atgcttgaac ttacaggaca gaatttcact     1320

ccaaatttac gagtgtggtt tggggatgta gaagctgaaa ctatgtacag gtgtggagag     1380

agtatgctct gtgtcgtccc agacatttct gcattccgag aaggttggag atgggtccgg     1440

caaccagtcc aggttccagt aactttggtc cgaaatgatg gaatcattta ttccaccagc     1500

cttaccttta cctacacacc agaaccaggg ccgcggccac attgcagtgc agcaggagca     1560

atccttcgag ccaattcaag ccaggtgccc cctaacgaat caaacacaaa cagcgaggga     1620

agttacacaa acgccagcac aaattcaacc agtgtcacat catctacagc cacagtggta     1680

tcctaactac cgtctttttg ctaggactta aactgacttg agtgtggcaa aaagttaaca     1740

aaaaaggaga aaaaatgaac aatcgtttgt ggtttcttgg gaaaactttt cataccaggt     1800

gatactattc aaaaaccccg ttgtctccct gcaagtgctg atttgaaatg cagaagccac     1860

agtaaaaaaa aaaaaaaaaa aaaaaaaaaa gaaaaaaaaa tcaaaatgta taaatattgg     1920

aaatcaagtt tttcagctgt tttgttggtt ggttggttgg tttttgtttg gttttgttta     1980

aatgggcaag aagtaaataa tgtggctgga atacaagttg aacaaactag aagacacaaa     2040

tctaacatag tttttatgga ccaaggaact tgtatattgt ataagcttta gtaaaaggta     2100

cattttcacc ataccttttt ttatatcacg gtattatagt acaccttgtt accaaatagg     2160

ttgttctctt ccccacccac ctttgagctt ttgctctaaa atacattcag gttccaagcc     2220

tgaccatcct tgtttaatct atcatactct tccaggtttt ttttttttgg tctaaggctg     2280

gaactttttt cttttttttc agctgaagtc ttatgacttt tcatgagtca aaattgtttg     2340

gatttcagca agtcaaatct tgcaaaggcc tgcatatttt ttttaagatt atatgaagtc     2400

tgtgcaaaag ctttaaaaaa atgcctctgc cttgcctgca atacatgcaa tgtatgttaa     2460

cttagtctct cttctcagac actgttggta gttatttctg tgttttcctt tttttaaaaa     2520

aaaatatgga cttattgtgg ttatctgaga ggttctaaca ttcacatgca atttggtgtg     2580

gccatttagc tattaatgag ttaatggcgc agaacttgtt gatatttgaa gtgttctctc     2640

cccttttccc atgacgtaaa tacataggtg tgttccagga tttgttcagg tttttccccc     2700

ctcctaatct tgtacataac ttgtattatg tgtaagttaa acattttatt ttgaacttgg     2760

aatgttccca gtgatttcat tcagcagggt attttctgcc ttgttggcaa gtgacaaaaa     2820

atatgggaag tatttgctac cagttggtag atggtgccct taatggtaga atgaggaaaa     2880

tgtccgcaaa agcatgtttt attatcttta cttttttggg gggttggagg gggtagccta     2940

gccagaacat cattgtaatc ttaaaacata agatgctttt attagatgat caactaaaat     3000

agctggaaga cagtacttta gaaacagata gttgtaagat tataaaatgc aaatgtaact     3060

tatgttttca tttttttctc tgcctttttt gtttgtttgt tttctctttt ccagtactga     3120

gcatctccac aaatgtctcc taactcagaa aatgtttctt ttcttttcag ttgagatttg     3180

gttgcattca gggttgtagg ttggccttgc ttgctaaccc cgccggtttt accgtgcttt     3240

cattcctgaa ctttgtttat gcctttgttt ggtttcttcg aaattgcagc agactcattg     3300

ggctacattt agtacaggaa ccacgtgtgt aatgttatac aacacagtct agtaatacaa     3360

tcatccctct tagagtaaaa actacctcta gattgtggta agcttttact gtcccataaa     3420

acaggagcca cagtacctta tgaatgcaaa actgtaactt cctacagtgt ttccctacag     3480

aacattgtct ttctggtgtc ctgggctgtt ttgaaaaagt ttccattaat agacttttta     3540

gaaattatta ttagtagcat tttttttcca gctttgctgt cttcatcact cactctatgc     3600

tcagactatg ccactgtaaa tattcttcct aacatcttta aatcgccttt tcctcagttt     3660

tcaaggggaa ggtcatttgt aaagcacgtt aggtggttaa atcagttatt gcggttttct     3720

cttactgcaa gcctttttaa tcacccccag gctgcatttt attctatatc gccttttttc     3780

ttcaaatctg ctccaatcac tcacttctct cttataagct aatcctgcct cacaccttaa     3840

atctgtttca gtgatcaagg gcagaactca ttgtggcctt atctttcttt gttgtaattg     3900

ttcactgtct ctttcttaca gaccacttat ttctgagtag tagttattcc tctctatgga     3960

gtcatggcag gaatcattac acagtgcttt tgttcagagc atggacatgt tcctagtgct     4020

gctttgcttt aacggccaca agtttcctcc acttcctagg tttggtattt agttaaggaa     4080

tcatattaaa ttaaccaata acaaaagaga tacttttgaa gaacaaacta ttccttaccc     4140

atttttgtag ctcaaaaata atttttcaag ttcatgacct tattaaaatg aacttgtgtt     4200

tttttaacaa acatgtatgt tttattttga tagtttcttt ccgtaagata attgaaatat     4260

tatactgtaa acccttttct tttctttttt tgaaaagtcc aagaatgtac ttatacaggc     4320

atttttcccc acctattttt ggccattctc ataccacaga ctaaagagtg aaatgatttg     4380

tccattgtag cttattgttt atcagtagtt cttttgtcag ctgcttacat tttttctttc     4440

atggttttgt gaatcatttt cagtatgtaa tttataggaa ccttgtcctc tggttatagt     4500

agactgtgtg ccctcctcca gtgatggcat tattagacat gctggtcatt taccctcaga     4560

aagactctct tattagaatg gtgagtgctt cagttatagt atgtttgaat ttttaaaaaa     4620

ttctgtttta gaaatgtatc ttatgctctc atgactatgc agtttctaaa catacacata     4680

gaagctgagt ctctgatcca atatgttttt atttgttcca tttaatttat cacatagatt     4740

gggaaggcaa gctaaaagcc ttaaaaatgc cctttatatt ttgagtgatt tcagcgttga     4800

acactagtat actatctaaa tttgctgctc actttcttta aactgtggca attaaaggca     4860

tgtttataca tgacttaatc gtgaaatgtt tgtcactctt actgcacaga cttatctgca     4920

atcataactg gttagttttt ttgttttgtt ttgttttatt gtttttaatg aaactggtac     4980

catctgtgct ttcacaaaaa acttccaatg ccatttttga gaactaacct aactagtcat     5040

gctaaccaga aaatccactg gggaggaggt tccttttgaa acaaaatgct gttcagttag     5100

taaccaagtt actttgattg caaaagcagc tgtgtttctg ataagtactg aacaaatgtg     5160

tgtaattttc tgtgccagac ttatgacttt gttttcaagc actgtaatgt gggatggatg     5220

gttagaaaca ataatatatt agggtttctg tttaaccctt tcaggactga actgtatctc     5280

cttttgttaa ttttcccctg tgttgtgata aatgtttgcc agcattcagt actgtgttgg     5340

tccagatgta ggtttatatg ctcattttta gcttatttct tgtaccttgc agcatgctct     5400

acgcattcag tccttaaggg gtttatttta caaactgtgc gcctgtaagg tttattagca     5460

ataagataga aaattgagca agtttatacc ataattttgt agaaaaaaag aatctgctca     5520

gttccatatt tcatccgtga aaaacttgca atacgagcag tttcaaggaa taaataaaaa     5580

ggaaatgtaa accattgtaa aagtcttctg tcgaatgtgc ctgatgcatg tattatcgtc     5640

ttttatttca gaatacttca taaagataaa attaaattct atattatagt tggtgtattt     5700

acaatcttac catgtacatc acatcaaagt gatagctcta ctaatttaat ttccttgtca     5760

atgtttttaa ctatatagtg ctttaaagag attttttttc cctgtgtaaa aaaaaaaaaa     5820

aaaaa                                                                 5825


<210>  2114
<211>  2892
<212>  DNA
<213>  homo sapiens

<400>  2114
aactgagcga ggagcaattg attaatagct cggcgagggg actcactgac tgttataata       60

acactacacc agcaactcct ggcttcccag cagccggaac acagacagga gagagtcagt      120

ggcaaataga catttttctt atttcttaaa aaacagcaac ttgtttgcta cttttatttc      180

tgttgatttt tttttcttgg tgtgtgtggt ggttgttttt aagtgtggag ggcaaaagga      240

gataccatcc caggctcagt ccaacccctc tccaaaacgg cttttctgac actccagctg      300

tctgacaaca tctacccggt ggaggacctc gccgccacgt cggtgaccat ctttcccaat      360

gccgaactgg gaggcccctt tgaccagatg aacggagtgg ccggagatgg catgatcaac      420

attgacatga ctggagagaa gaggtcgttg gatctcccat atcccagcag ctttgctccc      480

gtctctgcac ctagaaacca gaccttcact tacatgggca agttctccat tgaccctcag      540

taccctggtg ccagctgcta cccagaaggc ataatcaata ttgtgagtgc aggcatcttg      600

caaggggtca cttccccagc ttcaaccaca gcctcatcca gcgtcacctc tgcctccccc      660

aacccactgg ccacaggacc cctgggtgtg tgcaccatgt cccagaccca gcctgacctg      720

gaccacctgt actctccgcc accgcctcct cctccttatt ctggctgtgc aggagacctc      780

taccaggacc cttctgcgtt cctgtcagca gccaccacct ccacctcttc ctctctggcc      840

tacccaccac ctccttccta tccatccccc aagccagcca cggacccagg tctcttccca      900

atgatcccag actatcctgg attctttcca tctcagtgcc agagagacct acatggtaca      960

gctggcccag accgtaagcc ctttccctgc ccactggaca ccctgcgggt gccccctcca     1020

ctcactccac tctctacaat ccgtaacttt accctggggg gccccagtgc tggggtgacc     1080

ggaccagggg ccagtggagg cagcgaggga ccccggctgc ctggtagcag ctcagcagca     1140

gcagcagccg ccgccgccgc cgcctataac ccacaccacc tgccactgcg gcccattctg     1200

aggcctcgca agtaccccaa cagacccagc aagacgccgg tgcacgagag gccctacccg     1260

tgcccagcag aaggctgcga ccggcggttc tcccgctctg acgagctgac acggcacatc     1320

cgaatccaca ctgggcataa gcccttccag tgtcggatct gcatgcgcaa cttcagccgc     1380

agtgaccacc tcaccaccca tatccgcacc cacaccggtg agaagccctt cgcctgtgac     1440

tactgtggcc gaaagtttgc ccggagtgat gagaggaagc gccacaccaa gatccacctg     1500

agacagaaag agcggaaaag cagtgccccc tctgcatcgg tgccagcccc ctctacagcc     1560

tcctgctctg ggggcgtgca gcctgggggt accctgtgca gcagtaacag cagcagtctt     1620

ggcggagggc cgctcgcccc ttgctcctct cggacccgga caccttgaga tgagactcag     1680

gctgatacac cagctcccaa aggtcccgga ggccctttgt ccactggagc tgcacaacaa     1740

acactaccac cctttcctgt ccctctctcc ctttgttggg caaagggctt tggtggagct     1800

agcactgccc cctttccacc tagaagcagg ttcttcctaa aacttagccc attctagtct     1860

ctcttaggtg agttgactat caacccaagg caaaggggag gctcagaagg aggtggtgtg     1920

gggacccctg gccaagaggg ctgaggtctg accctgcttt aaagggttgt ttgactaggt     1980

tttgctaccc cacttcccct tattttgacc catcacaggt ttttgaccct ggatgtcaga     2040

gttgatctaa gacgttttct acaataggtt gggagatgct gatcccttca agtggggaca     2100

gcaaaaagac aagcaaaact gatgtgcact ttatggcttg ggactgattt gggggacatt     2160

gtacagtgag tgaagtatag cctttatgcc acactctgtg gccctaaaat ggtgaatcag     2220

agcatatcta gttgtctcaa cccttgaagc aatatgtatt ataaactcag agaacagaag     2280

tgcaatgtga tgggaggaac atagcaatat ctgctccttt tcgagttgtt tgagaaatgt     2340

aggctatttt ttcagtgtat atccactcag attttgtgta tttttgatgt acactgttct     2400

ctaaattctg aatctttggg aaaaaatgta aagcatttat gatctcagag gttaacttat     2460

ttaaggggga tgtacatata ttctctgaaa ctaggatgca tgcaattgtg ttggaagtgt     2520

ccttggtgcc ttgtgtgatg tagacaatgt tacaaggtct gcatgtaaat gggttgcctt     2580

attatggaga aaaaaatcac tccctgagtt tagtatggct gtatatttct gcctattaat     2640

atttggaatt ttttttagaa agtatatttt tgtatgcttt gttttgtgac ttaaaagtgt     2700

tacctttgta gtcaaatttc agataagaat gtacataatg ttaccggagc tgatttgttt     2760

ggtcattagc tcttaatagt tgtgaaaaaa taaatctatt ctaacgcaaa accactaact     2820

gaagttcaga taatggatgg tttgtgacta tagtgtaaat aaatactttt caacaataaa     2880

aaaaaaaaaa aa                                                         2892


<210>  2115
<211>  6413
<212>  DNA
<213>  homo sapiens

<400>  2115
agaaatcaga gacgctgcct gcctgctccc atctctcgcg cgctctctct ctcttctgct       60

ctctccctcc ctttgcaaac attggattta aacctgctca gaattcagca cagaggaagg      120

cagcagcggt agcagcagca gaagcagtag caagcccggc agctgagagc accgcagcgt      180

cgagatgtac catcctgcct actgggtcgt cttctcggcg acaactgccc tgctcttcat      240

cccaggagtg cccgtgcgca gcggagatgc caccttcccc aaagctatgg acaacgtgac      300

ggtccggcag ggggagagcg ccaccctcag gtgtaccata gatgaccggg taacccgggt      360

ggcctggcta aaccgcagca ccatcctcta cgctgggaat gacaagtggt ccatagaccc      420

tcgtgtgatc atcctggtca atacaccaac ccagtacagc atcatgatcc aaaatgtgga      480

tgtgtatgac gaaggtccgt acacctgctc tgtgcagaca gacaatcatc ccaaaacgtc      540

ccgggttcac ctaatagtgc aagttcctcc tcagatcatg aatatctcct cagacatcac      600

tgtgaatgag ggaagcagtg tgaccctgct gtgtcttgct attggcagac cagagccaac      660

tgtgacatgg agacacctgt cagtcaagga aggccagggc tttgtaagtg aggatgagta      720

cctggagatc tctgacatca agcgagacca gtccggggag tacgaatgca gcgcgttgaa      780

cgatgtcgct gcgcccgatg tgcggaaagt aaaaatcact gtaaactatc ctccctatat      840

ctcaaaagcc aagaacactg gtgtttcagt cggtcagaag ggcatcctga gctgtgaagc      900

ctctgcagtc cccatggctg aattccagtg gttcaaggaa gaaaccaggt tagccactgg      960

tctggatgga atgaggattg aaaacaaagg ccgcatgtcc actctgactt tcttcaatgt     1020

ttcagaaaag gattatggga actatacttg tgtggccacg aacaagcttg ggaacaccaa     1080

tgccagcatc acattgtatg ggcctggagc agtcattgat ggtgtaaact cggcctccag     1140

agcactggct tgtctctggc tatcagggac cctcttagcc cacttcttca tcaagttttg     1200

ataagaaatc ctaggtcctc tgagcaacgc ctgcttctcc atatcacaga ctttaatcta     1260

cactgcggag agcaaaccag cttgggcttc tttttgtttt tttctgttat tctagatttg     1320

ttttcttttt gtttttgttt atttgtttgt ttgcttttat ttccagcttg aatgagtggg     1380

gttgggggcg gggtgggcag ggttctacca cgtgtaggat aatcattcat tggtgtgtcc     1440

aaaaatgggg tctgctcctg ctaccttgac ccttcccttt cctctgcttc tctcctcatc     1500

atcattccca acaacatcct ctgccacaca caacaaaacg taagtttcat ttgggcaaaa     1560

attgagcctc acaataaaca ccctgaagac acaacttgac ttataacata gtgcacagca     1620

agagctacat ccaagtgtcc tattatctgt gattattttc ttaatgacaa tgtacatatg     1680

cccccatcca tgttaattat tatctaattc cattagggtt cacgtctttt ctttctggga     1740

cactatccta ctatatccat atctatagat ttcaatatag atgattgtgc catcttctgt     1800

agcccctccg ctctactcat tccttccacc atctgcagag atttgaagtt tggggctatg     1860

catgaaaccc aacactaaat tttgcaagtc aagtaaccaa aaaaggggga ggcattttga     1920

agatagaacc tctattttaa aaagagaagt tcaactcata aacgtgattg ataggtggct     1980

gatttattta ggttttgtca agctatctat caaagtaatg gtacagttac ccatctactc     2040

aaatatctga tttatctcac catccaatta tctacccacc tgtcttcctc tctagcaatc     2100

tatttactgt ttatcaatct atcaatgtaa ttgtctaaca ctcctttcta ttctctccct     2160

actactcact atcaattcat ccccatatga atctctaacc atattgtatc tctcccactg     2220

tattcattta tacaccatca gcagacattg gcatcttcaa aattatcttt caacttctgt     2280

gaaagccaac gatctcacag gttaacaaaa tacaaaagca ataccctgtg ttgtggactc     2340

tttaaaatct ggtatcctat ccacccaagg gagacactaa cagataggcc aaagtagcaa     2400

gctaatgatc agtcactcac tattcccaga agagcctgtg ttttctaaaa cactttcttg     2460

ggaagcagat cagcctagaa aagttttgat tagcactgtg gttttccttt tgcacttgaa     2520

ggacaaaggt gccagccttt atgcttctct caacccttca agaaagtaca tgtcaggaac     2580

ctatggctgg ctttccttag cagcaagaac ttgagagaaa aacacatctg tctctgcaat     2640

gcaaagtgaa gagtccaccc gcctgagtgg gatgacttca gctagagtct cctttctgct     2700

ccagttctgg tttaatctgt ttgaaaacta tccagtaaaa agctgatgga ggccaattac     2760

atggcgggtg tattgacaac tctggtattt gtttcaggaa gctcttctaa gctgagggca     2820

cttgagcaac tgacttaatt ttcaagcact tgattaacac aacactgcaa acagaaggga     2880

gaaagtgtca gtgacacagt ttcctctgat gcagctgctt ctccaatggc tttggggaag     2940

aacttcacca gctcttcagg ttcaaagcag acccagcata caaacaagag ctgagccacc     3000

tttgctgtct tgtctcctgg gacgagaagg actcatccag caaagttgcc tgggattcaa     3060

aataaaggca ttgcagaccg cacaggtgtg ctgcagggac tgatccacag agaggatgag     3120

aatgcagcat caatcgcaga cctgccctgc ctcagttgga aaaccttttc aggccctcag     3180

tctaaaaaat aaaaaatatg agcaccattg aattctgtgc ccttaatgct taactggtct     3240

tcttcctctg gtatcagtgt cctctttgtt tttgtccatc aaggcacatg agtgtgacct     3300

ctgccatggg gaaacacaca cagagatatc tatacatata tacatacata caaacatagg     3360

ctatcttggc acactaaatg ctaagcactg tcttaagagg tagagctggt gtgagtgaaa     3420

ttaatgttac attttccagc tgtaaacaga catctgcatt tcctagtgag ctgccaggag     3480

ccagattcgg gaaccgtaac tgatgtgcca ggaatggtgc attgattccc agttccaggg     3540

atgatcatga gcaggcgcaa aatcagaatt aaaggtcgca catagacgtt tcagatctgt     3600

caccaccttc agcatctgga gttgagttgg tgtcagatag tgtatgagaa ttaaatgtgt     3660

catctgagca tgctactgat gataaatttg ttactttgga gttgaataaa tgtgaaggct     3720

gtgaagagtg gacagtcttg gagaacacag tgcttgaaat ggacaagctg gacctattcc     3780

tcactccaag acttgttcta caggaaaggg tccatgctcc tttggccaag atcatcagaa     3840

cctctcaacc caacaaggct ggcttcaggg ccactatgga accctgctgt tcccccttcc     3900

aaaggatact aagatgcccc tctggtgggt acctatccca gccacgtttc agagggagag     3960

aaatgctaca gttgatcctc atctgtctgg ggtaaagaca acaaagtaaa tacaacccaa     4020

ggcaactggg gtactcactg ggagtgaaaa tgacttcttc acaacagaca tatttctgct     4080

tctgtgtttt tgtgtttctt tggtggggat ggcttcatgg gagagtggct gtcacccatc     4140

attttgaagc atatagaaca acaaatgctt acacaagaca atatccacac ttttccaact     4200

tcacacacgg agagtacatg gagaatgcct acaggctaga tttgttcagg gtgccagtag     4260

tgggcatggg gtgggggcaa ggcaggacaa aacatacaag tctgagcaag tacatctctt     4320

gcaggttttc cacatgaaaa ggaagccaaa taagtcctgt taggagatta ggtgagagga     4380

attagcaatg tagggactct gaaacccttc cccttcccaa aacagagttc atatgcactt     4440

ccaccaaagt aatgccaatg aaagtgctcg tgttaaggct gcagccaagc ttgtttttca     4500

gtagtttaat gtcaagtgcc tgatacagtc gactgcaagt ctaaacaagc atgtttagtt     4560

tttctcattc ttgctttaat tcagggaggg ggagatgtag agaagtggtt gtgaaaacat     4620

gtacaggctt tatgcagagc actgcgcatg gctgttctgc tgcaactgtg ctccacgaaa     4680

cagaagaaaa ggtaaggtgt tgtgtcacaa agaggcccca gtctctttct tcttacatcc     4740

atgcctctta ctagatgata catttacaga ttgggcagtt tgttctcaaa acctgggtga     4800

gaagactatt cctggactct agcaacttca aaactgaggc tgggtttcag aatctttttc     4860

tgcatcaatt cagtcaattt gccttcaaca aagagaagtc agcaagttct atttatgctg     4920

aaagaactat tccatgagaa aagcagagaa ccccaaagtg ggcaggcaac cccgacgaga     4980

gcttatccct gtggcggcat caggagtggc tgtacattga attttcaagt gctggttggc     5040

tgtcgccagc ccatggtagg aggggaggaa tggcttaaga tgaggtaaga tctggtggtg     5100

gggcatcttt cctcaattcc atactgactt tgatcttgag aaagaaaaac tggctatgca     5160

ttacctaaaa ccagtccaaa atgaaacaga ccaacacaca cacaaaagca aattgtcaat     5220

ccctttggaa ttaagggaag cagcataagg tttttctttt tggaaaaaat gcatttattt     5280

tctttttctc caacagcaag aatcttttgt tttcattttg cacgtgacct tatcttggaa     5340

actcttatac ccaattgcct cccctcctat tattcagagc ttccctgtct ttttacttga     5400

agacaaataa gtttgagcac ttgagtaaaa cttcacaggt gtgtaagtag gaaggcaaca     5460

ttttcaaaaa gagaccatat gatgagaacg cctaatgatc accacatgca aacaaacaaa     5520

actgccagtc tcatttccca catttcttac ttaagagaag agaagtaaat gaaaggaaga     5580

agaaatagat ttgtaattaa agatgtggca aaaaagatag ggctgagcca gttcaattta     5640

gccttcaggt gcagaatact tagagtccaa agaaatgtgg agtggactta attagatgca     5700

gttgtcttta tcctgaaagt agtgagctaa gcctaatttc cagcattttg aaagagattc     5760

ctttttgttt ctttccatgg tgccctcttt aaggcacaga gttgctccac accactgggt     5820

ggagaaagaa agattgcgaa ccctcgacca tccttttgag gctacattct atgttatttg     5880

gcagatttat aaagctatca gtaataacaa tgctatgtac tgcaagctgc ccttgtgtta     5940

gttaaaggga gcatttttaa tcgttcggaa attttcgtga catgtcaagt gcagttgtga     6000

ggactgtgtg ggtgaacgaa aatgtgtctg tcaagttcag agtcctttag atttaaaaaa     6060

aaattatgac ttatcaatgg tgccgttata gctgtgtcag acaatgggtg tgcccattct     6120

cacaattatc cttcaaaaaa aatctatgtt caaatgcttt aaaaatttat cacacgatac     6180

aagagtatga ctttgtcagc cttctagagt tctttttttc ttttattttc tttcgtattt     6240

tttccttcaa aaaatcaatg aagacttgat ttctgtcaat aattgtatca agggtgaata     6300

tactacctga attttgtgca tgttacattg tagttgtaac cttttctaat tcaggatgaa     6360

tacgagatgg ttgtgattgt gcagtgtacc aataaagttc gagaaatttg taa            6413


<210>  2116
<211>  7259
<212>  DNA
<213>  homo sapiens

<400>  2116
cactagaatg tgaaggatct tcgcggttct gggtgcccag aaaggcggcg acgcggcgga       60

tgacaacatt aggccgcgac gcgctcctgg ccaggcggcg gctgtagtgt tagctttgga      120

cgccgcagta gccgctgccg gtagcaagcc gactgaggga aggtgggggt ccgcccgggc      180

tggtggacct cggggccgaa agttcccgcc ccgctcgggg gctgagccgg cagtgcctcc      240

gcggccgctg ggcagcgccc ttcgtccagg ctcgcgcccc agctgccgcc gacgacagcg      300

gccgagagaa gttggggtct gactagacgc ttacggggcc tcggaccccg gcgccgcggc      360

gacctcggag gaaccggctc cttgcgtccc gcctccctgg gagctccgca cgggatttgc      420

agatttacag aatggctgca cattaatgga aagagaagca taaacctatc ttctttcatt      480

atggagggag gtttggcaga tggagaacct gatcgaactt cgcttcttgg tgatagcaaa      540

gatgtccttg ggccatcaac tgttgtagca aacagtgacg aatctcagct tctgacacca      600

ggaaagatga gtcagcgcca aggaaaagaa gcttatccaa cgccaaccaa agatttgcat      660

cagccatctc ttagtccagc aagtcctcat agccagggtt ttgaaagagg gaaggaagat      720

atttctcaaa ataaagatga atcttcactt tctatgtcaa agagcaagtc tgaatctaaa      780

ctttataatg gctcagagaa ggacagttca acttcaagca aactcacaaa aaaagaatct      840

cttaaggtac aaaagaaaaa ttaccgagaa gaaaagaaaa gagccacaaa ggagctgctc      900

agtacaatca cagatccttc tgttattgtt atggctgatt ggttaaagat tcgtggtact      960

ctaaagagct ggaccaagtt atggtgtgtg ttgaaacctg gggtgctact gatctataaa     1020

acccaaaaaa atggtcagtg ggtaggaaca gttcttctga atgcctgtga aatcattgaa     1080

cgtccatcaa aaaaggatgg cttttgtttc aaacttttcc atcctttgga gcaatctatt     1140

tgggcagtga agggtccaaa aggtgaagcg gttggatcca ttactcaacc cttacctagc     1200

agttatttga tcatccgagc tacttcagag tcagatggaa ggtgctggat ggatgctttg     1260

gagttggctt tgaaatgttc tagtcttctt aaacgtacaa tgatcagaga aggaaaggaa     1320

catgacctga gcgtttcatc agatagcaca catgtgactt tctatggctt actacgtgct     1380

aacaatctcc acagtggtga taacttccag ttaaatgata gtgaaattga acgacaacat     1440

tttaaggacc aagatatgta ttctgataaa tctgataaag aaaatgatca agaacatgat     1500

gagtctgata atgaggtgat ggggaaaagt gaagaaagtg acacagatac atcagaaaga     1560

caagatgact catatatcga acctgagcct gttgagcctt taaaggagac tacctacact     1620

gaacagagcc atgaagaact tggagaggca ggtgaggctt ctcaaacaga aactgtatct     1680

gaagaaaaca aaagccttat ctggacacta ttgaaacaag tccgtcctgg catggaccta     1740

tccaaggtgg ttctgcctac atttattttg gaaccccgtt ctttcctgga taaactttca     1800

gattactact atcatgcaga tttcctatct gaggcagctc ttgaagaaaa tccttatttc     1860

cgtttgaaga aagtagtgaa atggtatttg tcaggattct ataaaaagcc aaagggactg     1920

aagaaacctt ataatcctat acttggcgag actttccgtt gtttatggat tcatcccaga     1980

acaaacagca aaacttttta tattgctgaa caggtgtccc atcatccacc aatatctgcc     2040

ttttatgtta gtaatcgaaa agatggattt tgccttagcg gtagtatcct ggctaagtct     2100

aagttttatg gaaactcatt atctgcaata ttagagggag aagcacggtt aactttcttg     2160

aatagaggtg aagattatgt aatgacaatg ccatacgctc attgtaaagg aattctttat     2220

ggtacaatga cactggagct tggtggaaca gtcaatatta catgtcaaaa aactggatac     2280

agtgcaatac ttgaatttaa actaaagcca ttcctaggga gtagtgactg tgttaatcaa     2340

atatcaggga aacttaaact gggaaaagaa gtcctagcta ctttggaagg tcattgggat     2400

agtgaagttt ttattactga taaaaagact gataattcag aggttttctg gaatccaaca     2460

cctgacatta agcaatggag attaataagg cacactgtaa aatttgaaga acagggagat     2520

tttgaatcag agaaactctg gcaacgggta actcgagcca taaatgccaa agaccaaact     2580

gaagctaccc aagagaagta tgttttggaa gaagctcaaa gacaagctgc cagggatcgg     2640

aaaacaaaaa atgaagagtg gtcttgcaaa ttatttgaac ttgatccact cacaggagaa     2700

tggcattaca agtttgcaga tacccgacca tgggacccac ttaatgatat gatacagttt     2760

gaaaaagatg gtgttattca gaccaaagtg aaacatcgta ctccaatggt tagcgtcccc     2820

aaaatgaaac ataagccaac caggcaacag aagaaagtag caaaaggcta ttcctcccca     2880

gaacctgaca ttcaagactc ctctggaagt gaagctcaat cagtaaaacc aagtacaaga     2940

agaaagaaag gaatagaact gggagacatt cagagttcca tcgaatctat aaaacaaaca     3000

caggaagaaa ttaaaagaaa tattatggct cttcgaaatc atttagtttc aagcacaccg     3060

gccacggatt attttctgca acaaaaagac tacttcatca ttttcctcct gattttgctt     3120

caagtcataa taaacttcat gttcaagtag aagttctcta ccattgaatc agtgaactag     3180

aaagatctga tttggcctgg gaccagtgtt caagttggtt tggtctttat taaaaatcac     3240

aatattccga aaacaaaaaa acctaggaga taaatgtaga ggtattgact tttcgtatct     3300

tttatcttca cactgaaaca agagctatcc tatttgatta ttaaagtgag ctatgtgtta     3360

agtgccagga catttctagc ttttgtgaga atgtgtctac atatgagtat aataaaccca     3420

catgtataca caattgtctc ttatgtactc ctacctgaca gtagtctttg tattctatag     3480

tatgttctga gatataatgt taacattgtt cataacaaaa aatgctatca atcttataaa     3540

tatatgtaat ctattttctt cataaaacag gcacaaaagt tttatcagta aggaattaca     3600

gattgagaaa tgatggaata atagacataa ttaattcaat acactactgt taaaatcatt     3660

tgcaaagcac tcagctcaat tatcttctta gaaagaaaga aaaagtatga atggtcaaaa     3720

tgaatacatc gagagagata aatggcaaat tgctttttta aaagtttaca taagtttttt     3780

ttaaccccta gaatttaata tttgtagatg caggtaaata tatatactta cgtgtatatc     3840

agtataaaaa cactggtgtg caattaattg gattgattat aataccacct taagcacttg     3900

ctgaaaaaag tgtggtcaaa attgattgct gtccttttgt cttatttttg tttttcttaa     3960

gtcagctggt tcataacata ggccaaattc tagagatgtt tatagagcat ttgaagtgct     4020

gataatttat gttttttcat tatgaaaact tattttagct ttagactcca gtgtgttcag     4080

tgaataagta gaatataaaa aaatataacc agtattttac ttcaaaagcc aaaaagaggc     4140

aataagaaaa gacactttgt ggtggccttt atgtgtgcat taaaattggt ttctgtaaaa     4200

cgtgtaataa gttgagtatc tacgaagagt atcaagttct gaagtttaat ttttttatta     4260

tcctcctctc ttcttagtaa cttctttctg tggcaaaacc acaattcttt aagattccta     4320

ttgttcaggc taaggcaaat ttttttgttt gtttcttcag tttaatattt tgattttgtg     4380

tttttacgta aatatttata ttccttgaaa gcaatttttg ccaaggtagt tcagtttagg     4440

aatatgttgt tctaaaatat gtcttagaat cctgaaagca tagattttga aatgtttttt     4500

taatgaaaat gaaggtcaga gagaataatt gccctgacca catttgcctt tcagtaggag     4560

gaggctgtga aatagtaaaa ttataatcgt ttatgccatg ataaatacaa gattggtaaa     4620

taaatacatt gattggtaaa ttatgagaat caaaatgata aaaagagcct gcttttttcc     4680

ctaaccaata tagctatctt aagtatcctt aggtttctgt gaagaaccat ttcccatgtt     4740

ttcttggcaa aataatgctg tattccatat gtacatgtga aatgatgttt taaattgata     4800

aaagcttaaa taagatctac ctatacccag tattttcatg atattagaac aaatgggttt     4860

ttggttatat tttatatttg tcaatataat ttttgtattc acattctgtt acactctgcc     4920

tattcattga tatatgatat tctgtaaata ttgtacaatt tgatcttttt tatggtttaa     4980

attagttaat tacatacaaa ttgattggct tatcacaaaa atcatttcat cagtaaacct     5040

tgttaacatt ttgtactggt gacccacctc ttaggacttt ggtcttatcc acgtgtatgt     5100

tgttttcatt tggtccaaat aatattttat ttgtatgggt atcttctaag actaaatagg     5160

tagttgtgtt ctttattttt aaaatttctt tttagagcaa atgttatggg ttcttaccca     5220

aagagtcaaa aactatttct taagaaagag cagagttatt catgactgtt ctttatacac     5280

taaaagcatg catctaatct aatagtcctc ttattatgct tttagttgta tgagtctctt     5340

tctatgaact gaacacaaaa ctcaggaatt ggtggcttaa ttttagatca gtgcttgtac     5400

taggcttagt tatatgaatc tttataacac ataattacta actttgtagc catatatgta     5460

attgactttg aatgttattt acctgaaatt aatcttcctt cacacatgga ccgtaaacgg     5520

ttcccagttg tctgagagcc tcatgagggt ttctaggatt tatgacctta tgaccagttt     5580

ttttcattta ccaagatttt attttcctac atgaaaattt aattgagtaa taattattca     5640

catgtgcatt ttctttttag ctgttaaatg tactatgcca tcatccacca tttagtaaaa     5700

tgtagctggc ccaggacatg taaaaaaaaa aaaaaaacaa caacaataaa tagggcatgt     5760

gaaatgttaa gttacagcaa tagatatttt atttgtattt catgttagta cttttttgtt     5820

ttatatcact tataaaggta cagtgtactc tttgtcacag ctcagttggt aaccgcattc     5880

cattgaaaag ttggccttgt aaaatacaac tctcatttaa tattcatgct tttgtgcctt     5940

taagaaaata ttttttgtca ttttttgtgt tacagaacta taatgtgatt caaggtgttt     6000

ataggcttgt cataaaaggg tcatttctgt gtgttacttt ctttttatat agctatagta     6060

tatttaaaca ataatactat cttttatagg ggtttgtcta tttacctatt ctttactcag     6120

acattgatgt agacttgtca gattattctg agtattgtta acagtgcctt ttcgatggaa     6180

tcacactttt tggctgtcac cttgtgccat atacacacaa aattttgtgg aaggcagttt     6240

taactttctg aagaatatct gtcaaaattt aagaaaacaa atgtataaaa ttccattttt     6300

tccagtgttt agcatttcta gtaagcagtg aggttgtttg acatacagtg atgatggcat     6360

tattgataag ccatacatga gactgcagat tatattgaat catattaaat gtacagaaat     6420

aaaatattag atttatatca aattttccaa tttgaaccag tggggaaaat cccacagaaa     6480

tcagtaagtt tacatttcaa tttctatctt atttgactaa gtggaaagag attctttaaa     6540

atgtataacc tgccattatg taatttggtt tcattttatt ctacctgttg tgtgagttta     6600

gtatatttaa tttacttttt gttactcttt acatactgtt tatttttgtt agtttttaat     6660

tgaagatgga ctgttgaaat tgtataggac cagtgtctta ttaatatgat taatatattt     6720

agaagagcca cgtgaaaccc atgacaaaat gaatgtgaat attctttcta aaaatttaga     6780

aaatgttatc tttttgcatt tattatgtaa aactgtttta cagtatcaaa atttttcact     6840

taaagaaaaa aaatgccatg aaacatttga actgatgagc cacagaactt cagttgaaat     6900

ttttttcact ttttagcatg ctaaatatac atctgagttt aaatgttctg tttaatggcc     6960

attcataaat tcaagcacta ccactggtca gttttgtgtg atagaataaa aatatgttac     7020

ctgcagtgta agtacagcac actgtcaaat tcttttcctt aaggtgcaca gtaaatgtac     7080

agatagttat aggccactgt tttgtaatgt agtacatttc taatctatta ttcctaacct     7140

attataactg tttgcagaaa gaaaagaatt tttctaataa tctgtaaaat tatgctaact     7200

tctacaagta ggcttctaaa taaaattttt aaaaagagca aaaaaaaaaa aaaaaaaaa      7259


<210>  2117
<211>  7213
<212>  DNA
<213>  homo sapiens

<400>  2117
cactagaatg tgaaggatct tcgcggttct gggtgcccag aaaggcggcg acgcggcgga       60

tgacaacatt aggccgcgac gcgctcctgg ccaggcggcg gctgtagtgt tagctttgga      120

cgccgcagta gccgctgccg gtagcaagcc gactgaggga aggtgggggt ccgcccgggc      180

tggtggacct cggggccgaa agttcccgcc ccgctcgggg gctgagccgg cagtgcctcc      240

gcggccgctg ggcagcgccc ttcgtccagg ctcgcgcccc agctgccgcc gacgacagcg      300

gccgagagaa gttggggtct gactagacgc ttacggggcc tcggaccccg gcgccgcggc      360

gacctcggag gaaccggctc cttgcgtccc gcctccctgg gagctccgca cgggatttgc      420

agatttacag aatggctgca cattaatgga aagagaagca taaacctatc ttctttcatt      480

atggagggag gtttggcaga tggagaacct gatcgaactt cgcaaacagt gacgaatctc      540

agcttctgac accaggaaag atgagtcagc gccaaggaaa agaagcttat ccaacgccaa      600

ccaaagattt gcatcagcca tctcttagtc cagcaagtcc tcatagccag ggttttgaaa      660

gagggaagga agatatttct caaaataaag atgaatcttc actttctatg tcaaagagca      720

agtctgaatc taaactttat aatggctcag agaaggacag ttcaacttca agcaaactca      780

caaaaaaaga atctcttaag gtacaaaaga aaaattaccg agaagaaaag aaaagagcca      840

caaaggagct gctcagtaca atcacagatc cttctgttat tgttatggct gattggttaa      900

agattcgtgg tactctaaag agctggacca agttatggtg tgtgttgaaa cctggggtgc      960

tactgatcta taaaacccaa aaaaatggtc agtgggtagg aacagttctt ctgaatgcct     1020

gtgaaatcat tgaacgtcca tcaaaaaagg atggcttttg tttcaaactt ttccatcctt     1080

tggagcaatc tatttgggca gtgaagggtc caaaaggtga agcggttgga tccattactc     1140

aacccttacc tagcagttat ttgatcatcc gagctacttc agagtcagat ggaaggtgct     1200

ggatggatgc tttggagttg gctttgaaat gttctagtct tcttaaacgt acaatgatca     1260

gagaaggaaa ggaacatgac ctgagcgttt catcagatag cacacatgtg actttctatg     1320

gcttactacg tgctaacaat ctccacagtg gtgataactt ccagttaaat gatagtgaaa     1380

ttgaacgaca acattttaag gaccaagata tgtattctga taaatctgat aaagaaaatg     1440

atcaagaaca tgatgagtct gataatgagg tgatggggaa aagtgaagaa agtgacacag     1500

atacatcaga aagacaagat gactcatata tcgaacctga gcctgttgag cctttaaagg     1560

agactaccta cactgaacag agccatgaag aacttggaga ggcaggtgag gcttctcaaa     1620

cagaaactgt atctgaagaa aacaaaagcc ttatctggac actattgaaa caagtccgtc     1680

ctggcatgga cctatccaag gtggttctgc ctacatttat tttggaaccc cgttctttcc     1740

tggataaact ttcagattac tactatcatg cagatttcct atctgaggca gctcttgaag     1800

aaaatcctta tttccgtttg aagaaagtag tgaaatggta tttgtcagga ttctataaaa     1860

agccaaaggg actgaagaaa ccttataatc ctatacttgg cgagactttc cgttgtttat     1920

ggattcatcc cagaacaaac agcaaaactt tttatattgc tgaacaggtg tcccatcatc     1980

caccaatatc tgccttttat gttagtaatc gaaaagatgg attttgcctt agcggtagta     2040

tcctggctaa gtctaagttt tatggaaact cattatctgc aatattagag ggagaagcac     2100

ggttaacttt cttgaataga ggtgaagatt atgtaatgac aatgccatac gctcattgta     2160

aaggaattct ttatggtaca atgacactgg agcttggtgg aacagtcaat attacatgtc     2220

aaaaaactgg atacagtgca atacttgaat ttaaactaaa gccattccta gggagtagtg     2280

actgtgttaa tcaaatatca gggaaactta aactgggaaa agaagtccta gctactttgg     2340

aaggtcattg ggatagtgaa gtttttatta ctgataaaaa gactgataat tcagaggttt     2400

tctggaatcc aacacctgac attaagcaat ggagattaat aaggcacact gtaaaatttg     2460

aagaacaggg agattttgaa tcagagaaac tctggcaacg ggtaactcga gccataaatg     2520

ccaaagacca aactgaagct acccaagaga agtatgtttt ggaagaagct caaagacaag     2580

ctgccaggga tcggaaaaca aaaaatgaag agtggtcttg caaattattt gaacttgatc     2640

cactcacagg agaatggcat tacaagtttg cagatacccg accatgggac ccacttaatg     2700

atatgataca gtttgaaaaa gatggtgtta ttcagaccaa agtgaaacat cgtactccaa     2760

tggttagcgt ccccaaaatg aaacataagc caaccaggca acagaagaaa gtagcaaaag     2820

gctattcctc cccagaacct gacattcaag actcctctgg aagtgaagct caatcagtaa     2880

aaccaagtac aagaagaaag aaaggaatag aactgggaga cattcagagt tccatcgaat     2940

ctataaaaca aacacaggaa gaaattaaaa gaaatattat ggctcttcga aatcatttag     3000

tttcaagcac accggccacg gattattttc tgcaacaaaa agactacttc atcattttcc     3060

tcctgatttt gcttcaagtc ataataaact tcatgttcaa gtagaagttc tctaccattg     3120

aatcagtgaa ctagaaagat ctgatttggc ctgggaccag tgttcaagtt ggtttggtct     3180

ttattaaaaa tcacaatatt ccgaaaacaa aaaaacctag gagataaatg tagaggtatt     3240

gacttttcgt atcttttatc ttcacactga aacaagagct atcctatttg attattaaag     3300

tgagctatgt gttaagtgcc aggacatttc tagcttttgt gagaatgtgt ctacatatga     3360

gtataataaa cccacatgta tacacaattg tctcttatgt actcctacct gacagtagtc     3420

tttgtattct atagtatgtt ctgagatata atgttaacat tgttcataac aaaaaatgct     3480

atcaatctta taaatatatg taatctattt tcttcataaa acaggcacaa aagttttatc     3540

agtaaggaat tacagattga gaaatgatgg aataatagac ataattaatt caatacacta     3600

ctgttaaaat catttgcaaa gcactcagct caattatctt cttagaaaga aagaaaaagt     3660

atgaatggtc aaaatgaata catcgagaga gataaatggc aaattgcttt tttaaaagtt     3720

tacataagtt ttttttaacc cctagaattt aatatttgta gatgcaggta aatatatata     3780

cttacgtgta tatcagtata aaaacactgg tgtgcaatta attggattga ttataatacc     3840

accttaagca cttgctgaaa aaagtgtggt caaaattgat tgctgtcctt ttgtcttatt     3900

tttgtttttc ttaagtcagc tggttcataa cataggccaa attctagaga tgtttataga     3960

gcatttgaag tgctgataat ttatgttttt tcattatgaa aacttatttt agctttagac     4020

tccagtgtgt tcagtgaata agtagaatat aaaaaaatat aaccagtatt ttacttcaaa     4080

agccaaaaag aggcaataag aaaagacact ttgtggtggc ctttatgtgt gcattaaaat     4140

tggtttctgt aaaacgtgta ataagttgag tatctacgaa gagtatcaag ttctgaagtt     4200

taattttttt attatcctcc tctcttctta gtaacttctt tctgtggcaa aaccacaatt     4260

ctttaagatt cctattgttc aggctaaggc aaattttttt gtttgtttct tcagtttaat     4320

attttgattt tgtgttttta cgtaaatatt tatattcctt gaaagcaatt tttgccaagg     4380

tagttcagtt taggaatatg ttgttctaaa atatgtctta gaatcctgaa agcatagatt     4440

ttgaaatgtt tttttaatga aaatgaaggt cagagagaat aattgccctg accacatttg     4500

cctttcagta ggaggaggct gtgaaatagt aaaattataa tcgtttatgc catgataaat     4560

acaagattgg taaataaata cattgattgg taaattatga gaatcaaaat gataaaaaga     4620

gcctgctttt ttccctaacc aatatagcta tcttaagtat ccttaggttt ctgtgaagaa     4680

ccatttccca tgttttcttg gcaaaataat gctgtattcc atatgtacat gtgaaatgat     4740

gttttaaatt gataaaagct taaataagat ctacctatac ccagtatttt catgatatta     4800

gaacaaatgg gtttttggtt atattttata tttgtcaata taatttttgt attcacattc     4860

tgttacactc tgcctattca ttgatatatg atattctgta aatattgtac aatttgatct     4920

tttttatggt ttaaattagt taattacata caaattgatt ggcttatcac aaaaatcatt     4980

tcatcagtaa accttgttaa cattttgtac tggtgaccca cctcttagga ctttggtctt     5040

atccacgtgt atgttgtttt catttggtcc aaataatatt ttatttgtat gggtatcttc     5100

taagactaaa taggtagttg tgttctttat ttttaaaatt tctttttaga gcaaatgtta     5160

tgggttctta cccaaagagt caaaaactat ttcttaagaa agagcagagt tattcatgac     5220

tgttctttat acactaaaag catgcatcta atctaatagt cctcttatta tgcttttagt     5280

tgtatgagtc tctttctatg aactgaacac aaaactcagg aattggtggc ttaattttag     5340

atcagtgctt gtactaggct tagttatatg aatctttata acacataatt actaactttg     5400

tagccatata tgtaattgac tttgaatgtt atttacctga aattaatctt ccttcacaca     5460

tggaccgtaa acggttccca gttgtctgag agcctcatga gggtttctag gatttatgac     5520

cttatgacca gtttttttca tttaccaaga ttttattttc ctacatgaaa atttaattga     5580

gtaataatta ttcacatgtg cattttcttt ttagctgtta aatgtactat gccatcatcc     5640

accatttagt aaaatgtagc tggcccagga catgtaaaaa aaaaaaaaaa acaacaacaa     5700

taaatagggc atgtgaaatg ttaagttaca gcaatagata ttttatttgt atttcatgtt     5760

agtacttttt tgttttatat cacttataaa ggtacagtgt actctttgtc acagctcagt     5820

tggtaaccgc attccattga aaagttggcc ttgtaaaata caactctcat ttaatattca     5880

tgcttttgtg cctttaagaa aatatttttt gtcatttttt gtgttacaga actataatgt     5940

gattcaaggt gtttataggc ttgtcataaa agggtcattt ctgtgtgtta ctttcttttt     6000

atatagctat agtatattta aacaataata ctatctttta taggggtttg tctatttacc     6060

tattctttac tcagacattg atgtagactt gtcagattat tctgagtatt gttaacagtg     6120

ccttttcgat ggaatcacac tttttggctg tcaccttgtg ccatatacac acaaaatttt     6180

gtggaaggca gttttaactt tctgaagaat atctgtcaaa atttaagaaa acaaatgtat     6240

aaaattccat tttttccagt gtttagcatt tctagtaagc agtgaggttg tttgacatac     6300

agtgatgatg gcattattga taagccatac atgagactgc agattatatt gaatcatatt     6360

aaatgtacag aaataaaata ttagatttat atcaaatttt ccaatttgaa ccagtgggga     6420

aaatcccaca gaaatcagta agtttacatt tcaatttcta tcttatttga ctaagtggaa     6480

agagattctt taaaatgtat aacctgccat tatgtaattt ggtttcattt tattctacct     6540

gttgtgtgag tttagtatat ttaatttact ttttgttact ctttacatac tgtttatttt     6600

tgttagtttt taattgaaga tggactgttg aaattgtata ggaccagtgt cttattaata     6660

tgattaatat atttagaaga gccacgtgaa acccatgaca aaatgaatgt gaatattctt     6720

tctaaaaatt tagaaaatgt tatctttttg catttattat gtaaaactgt tttacagtat     6780

caaaattttt cacttaaaga aaaaaaatgc catgaaacat ttgaactgat gagccacaga     6840

acttcagttg aaattttttt cactttttag catgctaaat atacatctga gtttaaatgt     6900

tctgtttaat ggccattcat aaattcaagc actaccactg gtcagttttg tgtgatagaa     6960

taaaaatatg ttacctgcag tgtaagtaca gcacactgtc aaattctttt ccttaaggtg     7020

cacagtaaat gtacagatag ttataggcca ctgttttgta atgtagtaca tttctaatct     7080

attattccta acctattata actgtttgca gaaagaaaag aatttttcta ataatctgta     7140

aaattatgct aacttctaca agtaggcttc taaataaaat ttttaaaaag agcaaaaaaa     7200

aaaaaaaaaa aaa                                                        7213


<210>  2118
<211>  5733
<212>  DNA
<213>  homo sapiens

<400>  2118
tttggctgct cggagagtag gggggagagc ggatcccagc aggttaggcc ggaggaacag       60

cgccatgtgc tccgggctcc tggagctcct gctgcccatc tggctctcct ggaccctggg      120

gacccgaggc tctgagcccc gcagtgtgaa cgatcccggg aacatgtcct ttgtgaagga      180

gacggtggac aagctgttga aaggctacga cattcgccta agacccgact tcgggggtcc      240

cccggtctgc gtggggatga acatcgacat cgccagcatc gacatggttt ccgaagtcaa      300

catggattat accttaacca tgtattttca acaatattgg agagataaaa ggctcgccta      360

ttctgggatc cctctcaacc tcacgcttga caatcgagtg gctgaccagc tatgggtgcc      420

cgacacatat ttcttaaatg acaaaaagtc atttgtgcat ggagtgacag tgaaaaaccg      480

catgatccgt cttcaccctg atgggacagt gctgtatggg ctcagaatca ccacgacagc      540

agcatgcatg atggacctca ggagataccc cctggacgag cagaactgca ctctggaaat      600

tgaaagctat ggctacacca cggatgacat tgagttttac tggcgaggcg gggacaaggc      660

tgttaccgga gtggaaagga ttgagctccc gcagttctcc atcgtggagc accgtctggt      720

ctcgaggaat gttgtcttcg ccacaggtgc ctatcctcga ctgtcactga gctttcggtt      780

gaagaggaac attggatact tcattcttca gacttatatg ccctctatac tgataacgat      840

tctgtcgtgg gtgtccttct ggatcaatta tgatgcatct gctgctagag ttgccctcgg      900

gatcacaact gtgctgacaa tgacaaccat caacacccac cttcgggaga ccttgcccaa      960

aatcccctat gtcaaagcca ttgacatgta ccttatgggc tgcttcgtct ttgtgttcct     1020

ggcccttctg gagtatgcct ttgtcaacta cattttcttt ggaagaggcc ctcaaaggca     1080

gaagaagctt gcagaaaaga cagccaaggc aaagaatgac cgttcaaaga gcgaaagcaa     1140

ccgggtggat gctcatggaa atattctgtt gacatcgctg gaagttcaca atgaaatgaa     1200

tgaggtctca ggcggcattg gcgataccag gaattcagca atatcctttg acaactcagg     1260

aatccagtac aggaaacaga gcatgcctcg agaagggcat gggcgattcc tgggggacag     1320

aagcctcccg cacaagaaga cccatctacg gaggaggtct tcacagctca aaattaaaat     1380

acctgatcta accgatgtga atgccataga cagatggtcc aggatcgtgt ttccattcac     1440

tttttctctt ttcaacttag tttactggct gtactatgtt aactgagtga ctgtacttga     1500

tttttcaaag acttcattta acactgagtg aaatattact ctgcctgtca agtttttata     1560

cctgtacaca cacagacaca caagcagaca cacacatata tacatacgca attgtatata     1620

tatgtgaact ttctcagcat atatataaaa tacacgtgta tatgaggatg tatgtgtata     1680

tgtttataca cacaggagtc agtgcccatg tgtatggaag acaaatacac atacatatat     1740

acattttgca gctatggaca atttaccaca ggatgcatat taaagaaagt catagttttt     1800

ttctttttta attgaaaggg acaagtatca tctaaatatt atgccttgag aatgagggcg     1860

tgaaacacaa tatcatcccc aaatgtgtct tgtattatca taagttagat gttttagttt     1920

aaaaatcaga aagacattct tagttaatct ttgaaaactc atacagtggt attgctagtt     1980

taaaatgagt cacttacttc atatcctctc gttcagttta gtaagcaaag gcttcttggc     2040

ttctctggtg atggggtttg ttttcatcgg gcatacgttt tctgcaatgg tttagtggct     2100

ggggtgagcc actggcagtg tgcttacctg ttgtctgaaa catagataga tcccacgttg     2160

atgtctgaac gaccgtcttt tgaaaactca tcgggagtga atggcatctc gttgtaagta     2220

ctctaatata cagtgtgtag tttgtttctg ttgttcactt ggagtggatc cagcttcact     2280

gtcatgtgcg aacacagtga cacgtttggc cagtgacatt tcaatcactg aaaatgtgct     2340

ctacatctcg tatggatttc taggcctgat atccaacaga aagcatagac gtctcaggtt     2400

attcgttact ctaaggtaaa accatctagg atgattttcc cccttgcagt tatgttatca     2460

ttcttataac attgtatgtt aatagaaaat atatttgcat aatatgcata tatatgtata     2520

tttaccaaga ttttgtttct tacgcttgct atcatggcag catgcgatgt catattttcc     2580

tttatgtgat gtaactactt tctgttatct agaaattaag attgaagcta aaacacttct     2640

actgttcaat ttcagaaact aagaatcatc ctcatgcctt tatttctgta tctgacatat     2700

ttcataagca catccaacta ctcctagact gactaggatt ctgcaggaac atgacccgta     2760

cacaccacgc gtcacccaac gacccatgac cgttctctga ggcaaaggag ggcaacctga     2820

cagcaaacac agtcactgtt ggttccttct gatccacagc ctcatcagta tttggacttt     2880

ttaaagctcg tagaaacaag acaaggtgca ccggtttcat agacgcaacc ttaacttact     2940

atttagatga gatctttcta aagaaaaaaa aaagagatga tatatttttt gtaaacaata     3000

tttctatcac aggcatccat aaactgaaat gactacagtt gtgcaaacag gtgtcacagt     3060

gaagttgagc atttggagaa aaaaataaaa agcaaaattt gcaggaagaa ctgctaaatt     3120

aatactttat cccaaaatgc cacgtatgcc tcaccctctc tgttctatcc aaaaccaagg     3180

accagagtgc tccaatggta ggccccagtt gtctcgatgt aggtagaggc accaccctcc     3240

ccgaggatgc gtgtggtgtg gactatcccc atgagctgac cactacttga tttttctttg     3300

gtggccgtaa caacctttaa tttgtgggca tctgcaacag ttcaaaaccc accatcagat     3360

aaaacataat ccacaaaatc tcacgctaga ggcaattacc tacttttaga cccttttccc     3420

tctttcattc ctatcttttt cctcctaatc gctgctctct ggttttattt tcatctggag     3480

actagccagg gatttctttg gctttggctt ttctctgacc attttttcca tgggtaacaa     3540

tgggggatcc taaaagttaa acagattggg aaaaaccttg ttaagtggcc ttatcattat     3600

tatcatgtta aagaaaaaaa atacatttgc aaagacctta tccctttcaa tacttcaggt     3660

atctttttct gtatccagta attaaaggtg tgaggtccac atgcagaaga gggaccccaa     3720

aatgtaaatg gatgtggaca aaaacagtca atggtctatt taagtgtata atttatacta     3780

ttcagaactg tgacattaat tctttctggg agaaaagtga tttaaaactt ttttgatgca     3840

tagttgaggt acccaaatat caaaggcaga gaccccatgg ggctccaaag agctgcagtc     3900

tccttcccaa ggttttctgg atataaattt gcatggtata gtcataatag cttttgagct     3960

ttttatatgc atttggcacc aagactggga tccacaactt tgtagacact gcgatgaagt     4020

taacatatta gctatactat aaatagtgtt tgtaactaca cacacacaca cacacacaca     4080

cacaaataca tacatatatt ctgtaaaaac aaaaaaaaac tttttaagat ccttgggtat     4140

gtgtttgctt tactccattt cagaagaaaa ttacttttct tctaacaaaa ttattttata     4200

gcttctccat ttttaaaact tgtgagagca ttgagaagag aactctgact gtgttaacag     4260

aagagagttg aattggagtc tctgttgtgt taaaatgacc tctcgttact ccacagtagt     4320

tatttgagcc agtgactgag tcgcgttgag gaattctgaa cccggacctc tgacgttgtt     4380

gggaggtggc tgttacccac acccagacct cttgagtaag gacagaaacg ttatcattgg     4440

ggatataatg agatttcttt cttaacaatt gaaagtaata aagagttaat tttctcagta     4500

gtcctgtctt tccaaaatgc gccacagggg ctcaagatct acagaagaat cttgttatga     4560

cagtttgtta ttacccatat tcagatatcc ttgagataat ggaagagccc tgctacataa     4620

ctccctacag agaaagactg atagacttga gtagtcctta aaacaagtgt tattcctgtt     4680

caccaacccc gggactgtgg aggggtttca ctgtctatac catgcgacat ccatttcccc     4740

tgaatctcaa acgaactaga aagtatgtca tgataatatt tccattagat ttggaagcta     4800

cctgtacatc tgcaatattg tgtttttaac gccagcaccc agaactttga catgttcagt     4860

cactccctga aaggcacttc tctcttgtcc aaacacagcg ttgacatttt tactgaggag     4920

atcatctcaa aggtgatgcc aaacgagtct ggggctggtt ttaaggggac aggcacattg     4980

cagttgtagg tgttcatttt cagcatctag tagataatcc attggtgttt gtcccaccat     5040

tggtgtattc taacaagaat gtgtccaact ttgaatctcc tggcttgaaa gtataaacca     5100

tcacttaatt cttattttaa ctctccacct gaaaaccagt tcatatttct ggccatttta     5160

tgtaagcaaa actgaacaat tggtgaaaca ttttgttact cttggaattg actctggctg     5220

tcagtgtgag ccattagagt aacatcgaat cttggggcaa agaactgccc aggtgaatta     5280

aatttttcca ggacactagc tagtgtgcct tggattgatt acctcttcta ctgcattgaa     5340

aggcgccatg ttttcctgaa atactaaatt cccaacacct gggtaaacaa tgaccttcca     5400

gagagtggct cccgtatgcc tctccctagg accaacccca tgaacatgtt ttgtcacgtt     5460

tgtctcatgt ttctacttca caagtcagtg agtgtgttta aggtaagtac aggattattc     5520

tagtaggaat aggcgattgc tgtcataatc aattctcatg ttgatttcat tttattgtaa     5580

agataaattt aaacccagtt ttgcttaagc acattgatgt aattttttgg tattatttga     5640

catgaaaaaa cagcaaaatt gagtgataga tacaatatga aacttgttga tgaatgaatt     5700

caaatttatt aaaaaaggag taactgacct aaa                                  5733


<210>  2119
<211>  5733
<212>  DNA
<213>  homo sapiens

<400>  2119
tttggctgct cggagagtag gggggagagc ggatcccagc aggttaggcc ggaggaacag       60

cgccatgtgc tccgggctcc tggagctcct gctgcccatc tggctctcct ggaccctggg      120

gacccgaggc tctgagcccc gcagtgtgaa cgatcccggg aacatgtcct ttgtgaagga      180

gacggtggac aagctgttga aaggctacga cattcgccta agacccgact tcgggggtcc      240

cccggtctgc gtggggatga acatcgacat cgccagcatc gacatggttt ccgaagtcaa      300

catggattat accttaacca tgtattttca acaatattgg agagataaaa ggctcgccta      360

ttctgggatc cctctcaacc tcacgcttga caatcgagtg gctgaccagc tatgggtgcc      420

cgacacatat ttcttaaatg acaaaaagtc atttgtgcat ggagtgacag tgaaaaaccg      480

catgatccgt cttcaccctg atgggacagt gctgtatggg ctcagaatca ccacgacagc      540

agcatgcatg atggacctca ggagataccc cctggacgag cagaactgca ctctggaaat      600

tgaaagctat ggctacacca cggatgacat tgagttttac tggcgaggcg gggacaaggc      660

tgttaccgga gtggaaagga ttgagctccc gcagttctcc atcgtggagc accgtctggt      720

ctcgaggaat gttgtcttcg ccacaggtgc ctatcctcga ctgtcactga gctttcggtt      780

gaagaggaac attggatact tcattcttca gacttatatg ccctctatac tgataacgat      840

tctgtcgtgg gtgtccttct ggatcaatta tgatgcatct gctgctagag ttgccctcgg      900

gatcacaact gtgctgacaa tgacaaccat caacacccac cttcgggaga ccttgcccaa      960

aatcccctat gtcaaagcca ttgacatgta ccttatgggc tgcttcgtct ttgtgttcct     1020

ggcccttctg gagtatgcct ttgtcaacta cattttcttt ggaagaggcc ctcaaaggca     1080

gaagaagctt gcagaaaaga cagccaaggc aaagaatgac cgttcaaaga gcgaaagcaa     1140

ccgggtggat gctcatggaa atattctgtt gacatcgctg gaagttcaca atgaaatgaa     1200

tgaggtctca ggcggcattg gcgataccag gaattcagca atatcctttg acaactcagg     1260

aatccagtac aggaaacaga gcatgcctcg agaagggcat gggcgattcc tgggggacag     1320

aagcctcccg cacaagaaga cccatctacg gaggaggtct tcacagctca aaattaaaat     1380

acctgatcta accgatgtga atgccataga cagatggtcc aggatcgtgt ttccattcac     1440

tttttctctt ttcaacttag tttactggct gtactatgtt aactgagtga ctgtacttga     1500

tttttcaaag acttcattta acactgagtg aaatattact ctgcctgtca agtttttata     1560

cctgtacaca cacagacaca caagcagaca cacacatata tacatacgca attgtatata     1620

tatgtgaact ttctcagcat atatataaaa tacacgtgta tatgaggatg tatgtgtata     1680

tgtttataca cacaggagtc agtgcccatg tgtatggaag acaaatacac atacatatat     1740

acattttgca gctatggaca atttaccaca ggatgcatat taaagaaagt catagttttt     1800

ttctttttta attgaaaggg acaagtatca tctaaatatt atgccttgag aatgagggcg     1860

tgaaacacaa tatcatcccc aaatgtgtct tgtattatca taagttagat gttttagttt     1920

aaaaatcaga aagacattct tagttaatct ttgaaaactc atacagtggt attgctagtt     1980

taaaatgagt cacttacttc atatcctctc gttcagttta gtaagcaaag gcttcttggc     2040

ttctctggtg atggggtttg ttttcatcgg gcatacgttt tctgcaatgg tttagtggct     2100

ggggtgagcc actggcagtg tgcttacctg ttgtctgaaa catagataga tcccacgttg     2160

atgtctgaac gaccgtcttt tgaaaactca tcgggagtga atggcatctc gttgtaagta     2220

ctctaatata cagtgtgtag tttgtttctg ttgttcactt ggagtggatc cagcttcact     2280

gtcatgtgcg aacacagtga cacgtttggc cagtgacatt tcaatcactg aaaatgtgct     2340

ctacatctcg tatggatttc taggcctgat atccaacaga aagcatagac gtctcaggtt     2400

attcgttact ctaaggtaaa accatctagg atgattttcc cccttgcagt tatgttatca     2460

ttcttataac attgtatgtt aatagaaaat atatttgcat aatatgcata tatatgtata     2520

tttaccaaga ttttgtttct tacgcttgct atcatggcag catgcgatgt catattttcc     2580

tttatgtgat gtaactactt tctgttatct agaaattaag attgaagcta aaacacttct     2640

actgttcaat ttcagaaact aagaatcatc ctcatgcctt tatttctgta tctgacatat     2700

ttcataagca catccaacta ctcctagact gactaggatt ctgcaggaac atgacccgta     2760

cacaccacgc gtcacccaac gacccatgac cgttctctga ggcaaaggag ggcaacctga     2820

cagcaaacac agtcactgtt ggttccttct gatccacagc ctcatcagta tttggacttt     2880

ttaaagctcg tagaaacaag acaaggtgca ccggtttcat agacgcaacc ttaacttact     2940

atttagatga gatctttcta aagaaaaaaa aaagagatga tatatttttt gtaaacaata     3000

tttctatcac aggcatccat aaactgaaat gactacagtt gtgcaaacag gtgtcacagt     3060

gaagttgagc atttggagaa aaaaataaaa agcaaaattt gcaggaagaa ctgctaaatt     3120

aatactttat cccaaaatgc cacgtatgcc tcaccctctc tgttctatcc aaaaccaagg     3180

accagagtgc tccaatggta ggccccagtt gtctcgatgt aggtagaggc accaccctcc     3240

ccgaggatgc gtgtggtgtg gactatcccc atgagctgac cactacttga tttttctttg     3300

gtggccgtaa caacctttaa tttgtgggca tctgcaacag ttcaaaaccc accatcagat     3360

aaaacataat ccacaaaatc tcacgctaga ggcaattacc tacttttaga cccttttccc     3420

tctttcattc ctatcttttt cctcctaatc gctgctctct ggttttattt tcatctggag     3480

actagccagg gatttctttg gctttggctt ttctctgacc attttttcca tgggtaacaa     3540

tgggggatcc taaaagttaa acagattggg aaaaaccttg ttaagtggcc ttatcattat     3600

tatcatgtta aagaaaaaaa atacatttgc aaagacctta tccctttcaa tacttcaggt     3660

atctttttct gtatccagta attaaaggtg tgaggtccac atgcagaaga gggaccccaa     3720

aatgtaaatg gatgtggaca aaaacagtca atggtctatt taagtgtata atttatacta     3780

ttcagaactg tgacattaat tctttctggg agaaaagtga tttaaaactt ttttgatgca     3840

tagttgaggt acccaaatat caaaggcaga gaccccatgg ggctccaaag agctgcagtc     3900

tccttcccaa ggttttctgg atataaattt gcatggtata gtcataatag cttttgagct     3960

ttttatatgc atttggcacc aagactggga tccacaactt tgtagacact gcgatgaagt     4020

taacatatta gctatactat aaatagtgtt tgtaactaca cacacacaca cacacacaca     4080

cacaaataca tacatatatt ctgtaaaaac aaaaaaaaac tttttaagat ccttgggtat     4140

gtgtttgctt tactccattt cagaagaaaa ttacttttct tctaacaaaa ttattttata     4200

gcttctccat ttttaaaact tgtgagagca ttgagaagag aactctgact gtgttaacag     4260

aagagagttg aattggagtc tctgttgtgt taaaatgacc tctcgttact ccacagtagt     4320

tatttgagcc agtgactgag tcgcgttgag gaattctgaa cccggacctc tgacgttgtt     4380

gggaggtggc tgttacccac acccagacct cttgagtaag gacagaaacg ttatcattgg     4440

ggatataatg agatttcttt cttaacaatt gaaagtaata aagagttaat tttctcagta     4500

gtcctgtctt tccaaaatgc gccacagggg ctcaagatct acagaagaat cttgttatga     4560

cagtttgtta ttacccatat tcagatatcc ttgagataat ggaagagccc tgctacataa     4620

ctccctacag agaaagactg atagacttga gtagtcctta aaacaagtgt tattcctgtt     4680

caccaacccc gggactgtgg aggggtttca ctgtctatac catgcgacat ccatttcccc     4740

tgaatctcaa acgaactaga aagtatgtca tgataatatt tccattagat ttggaagcta     4800

cctgtacatc tgcaatattg tgtttttaac gccagcaccc agaactttga catgttcagt     4860

cactccctga aaggcacttc tctcttgtcc aaacacagcg ttgacatttt tactgaggag     4920

atcatctcaa aggtgatgcc aaacgagtct ggggctggtt ttaaggggac aggcacattg     4980

cagttgtagg tgttcatttt cagcatctag tagataatcc attggtgttt gtcccaccat     5040

tggtgtattc taacaagaat gtgtccaact ttgaatctcc tggcttgaaa gtataaacca     5100

tcacttaatt cttattttaa ctctccacct gaaaaccagt tcatatttct ggccatttta     5160

tgtaagcaaa actgaacaat tggtgaaaca ttttgttact cttggaattg actctggctg     5220

tcagtgtgag ccattagagt aacatcgaat cttggggcaa agaactgccc aggtgaatta     5280

aatttttcca ggacactagc tagtgtgcct tggattgatt acctcttcta ctgcattgaa     5340

aggcgccatg ttttcctgaa atactaaatt cccaacacct gggtaaacaa tgaccttcca     5400

gagagtggct cccgtatgcc tctccctagg accaacccca tgaacatgtt ttgtcacgtt     5460

tgtctcatgt ttctacttca caagtcagtg agtgtgttta aggtaagtac aggattattc     5520

tagtaggaat aggcgattgc tgtcataatc aattctcatg ttgatttcat tttattgtaa     5580

agataaattt aaacccagtt ttgcttaagc acattgatgt aattttttgg tattatttga     5640

catgaaaaaa cagcaaaatt gagtgataga tacaatatga aacttgttga tgaatgaatt     5700

caaatttatt aaaaaaggag taactgacct aaa                                  5733


<210>  2120
<211>  2752
<212>  DNA
<213>  homo sapiens

<400>  2120
atgtgggggc gcacggcgcg gcggcgctgc ccgcgggaac tgcggcgcgg ccgggaggcg       60

ctgttggtgc tcctggcgct actggcgttg gccgggctgg gctcggtgct gcgggcgcag      120

cgtggggccg gggccggggc tgccgagccg ggacccccgc gcaccccgcg ccccgggcgg      180

cgcgagccgg tcatgccgcg gccgccggtg ccggcgaacg cgctgggcgc gcggggcgag      240

gcggtgcggc tgcagctgca gggcgaggag ctgcggctgc aggaggagag cgtgcggctg      300

caccagatta acatctacct cagcgaccgc atctcactgc accgccgcct gcccgagcgc      360

tggaacccgc tgtgcaaaga gaagaaatat gattatgata atttgcccag gacatctgtt      420

atcatagcat tttataatga agcctggtca actctccttc ggacagttta cagtgtcctt      480

gagacatccc cggatatcct gctagaagaa gtgatccttg tagatgacta cagtgataga      540

gagcacctga aggagcgctt ggccaatgag ctttcgggac tgcccaaggt gcgcctgatc      600

cgcgccaaca agagagaggg cctggtgcga gcccggctgc tgggggcgtc tgcggcgagg      660

ggcgatgttc tgaccttcct ggactgtcac tgtgagtgcc acgaagggtg gctggagccg      720

ctgctgcaga ggatccatga agaggagtcg gcagtggtgt gcccggtgat tgatgtgatc      780

gactggaaca ccttcgaata cctggggaac tccggggagc cccagatcgg cggtttcgac      840

tggaggctgg tgttcacgtg gcacacagtt cctgagaggg agaggatacg gatgcaatcc      900

cccgtcgatg tcatcaggtc tccaacaatg gctggtgggc tgtttgctgt gagtaagaaa      960

tattttgaat atctggggtc ttatgataca ggaatggaag tttggggagg agaaaacctc     1020

gaattttcct ttaggatctg gcagtgtggt ggggttctgg aaacacaccc atgttcccat     1080

gttggccatg ttttccccaa gcaagctccc tactcccgca acaaggctct ggccaacagt     1140

gttcgtgcag ctgaagtatg gatggatgaa tttaaagagc tctactacca tcgcaacccc     1200

cgtgcccgct tggaaccttt tggggatgtg acagagagga agcagctccg ggacaagctc     1260

cagtgtaaag acttcaagtg gttcttggag actgtgtatc cagaactgca tgtgcctgag     1320

gacaggcctg gcttcttcgg gatgctccag aacaaaggac taacagacta ctgctttgac     1380

tataaccctc ccgatgaaaa ccagattgtg ggacaccagg tcattctgta cctctgtcat     1440

gggatgggcc agaatcagtt tttcgagtac acgtcccaga aagaaatacg ctataacacc     1500

caccagcctg agggctgcat tgctgtggaa gcaggaatgg atacccttat catgcatctc     1560

tgcgaagaaa ctgccccaga gaatcagaag ttcatcttgc aggaggatgg atctttattt     1620

cacgaacagt ccaagaaatg tgtccaggct gcgaggaagg agtcgagtga cagtttcgtt     1680

ccactcttac gagactgcac caactcggat catcagaaat ggttcttcaa agagcgcatg     1740

ttatgaagcc tcgtgtatca aggagcccat cgaaggagac tgtggagcca ggactctgcc     1800

caacaaagac ttagctaagc agtgaccaga acccaccaaa aactaggctg cattgctttg     1860

aagaggcaat cattttgcca tttgtgaaag ttgtgttgga tttagtaaaa atgtgaataa     1920

gctttgtact tattttgaga actttttaaa tgttccaaaa taccctattt tcaaagggta     1980

atcgtaagat gttaaccctt ggtatttaga aaattaaaac cttataatat ttttctatca     2040

agatgtatat tttacagtcg tgccttttac tctcattagc aaaaaagata aagattttat     2100

tttggtattt acaagaattc ccaggtacga agatatctgc atgggtggaa atcaggttca     2160

agcaacgtac tttgcattaa ctgataatac ctcagctgcg gggttaaagt tttcccagta     2220

tagagagact gtcactagga acattgtatt gatttattca ggtcattgag atcttctaga     2280

tgtattttaa aaagaatgct ttttggttat gtgttgctac cacagttaac actccataat     2340

gttcatgtca gccaaagagg actaaccaaa gctgaaatct cagagaacaa tttgctttac     2400

taagctgagt caacttgaga gcgaacttct aacaatgccg cactgtagtg tggctggttc     2460

taccactatg actttaaaac atgtttatat catttttaat ttttatgata cggtagtgtc     2520

agggagaaat gtaatgttct atatgaaatt cctttttcaa gtttgttcat taataacagt     2580

tattaattta aatcagcgtt agagtttgtg ctgctgcaac tgctgtgaaa atttctctga     2640

gtaattctga tttgtgaatg atcccagacc aaccctgaga ttttgtcaac ctgattaagt     2700

caatatgaat gattaaaaag atgtgagaac actgaaaaaa aaaaaaaaaa aa             2752


<210>  2121
<211>  4566
<212>  DNA
<213>  homo sapiens

<400>  2121
agagtgaaaa aggcgagcca ccaaaaccca tctccagtct cctcccgggg gcccccagcc       60

cgcctctgtg ccactttgca tcccacgccg gaggaggcat taacgagacc gggtaaggct      120

ttttaaacgg tccaaggtgt agagccatac ttcaggagga tcctcagaag ttttggacaa      180

gcctccccaa atgtggcagg tgctgtgctg gccattggtg acccaaagat gatgaaaaat      240

atgttcctgc ccacaaggag ttagcgacct actgggcttt cctcttgctg atgacatgat      300

tcctgtttga atctgttgac aagattctga aagctgaaca gagaattctg gcactgcact      360

gggtaggaaa aaggatgtct tccaagcgac cagcctctcc gtatggggaa gcagatggag      420

aggtagccat ggtgacaagc agacagaaag tggaagaaga ggagagtgac gggctcccag      480

cctttcacct tcccttgcat gtgagttttc ccaacaagcc tcactctgag gaatttcagc      540

cagtttctct gctgacgcaa gagacttgtg gccataggac tcccacttct cagcacaata      600

caatggaagt tgatggcaat aaagttatgt cttcatttgc cccacacaac tcatctacct      660

cacctcagaa ggcagaagaa ggtgggcgac agagtggcga gtccttgtct agtacagccc      720

tgggaactcc tgaacggcgc aagggcagtt tagctgatgt tgttgacacc ttgaagcaga      780

ggaaaatgga agagctcatc aaaaacgagc cggaagaaac ccccagtatt gaaaaactac      840

tctcaaagga ctggaaagac aagcttcttg caatgggatc ggggaacttt ggcgaaataa      900

aagggactcc cgagagctta gctgagaaag aaaggcaact catgggtatg atcaaccagc      960

tgaccagcct ccgagagcag ctgttggctg cccacgatga gcagaagaaa ctagctgcct     1020

ctcagattga gaaacagcgt cagcaaatgg agctggccaa gcagcaacaa gaacaaattg     1080

caagacagca gcagcagctt ctacagcaac aacacaaaat caatttgctc cagcaacaga     1140

tccaggttca aggtcagctg ccgccattaa tgattcccgt attccctcct gatcaacgga     1200

cactggctgc agctgcccag caaggattcc tcctccctcc aggcttcagc tataaggctg     1260

gatgtagtga cccttaccct gttcagctga tcccaactac catggcagct gctgccgcag     1320

caacaccagg cttaggccca ctccaactgc agcagttata tgctgcccag ctagctgcaa     1380

tgcaggtatc tccaggaggg aagctgccag gcatacccca aggcaacctt ggtgctgctg     1440

tatctcctac cagcattcac acagacaaga gcacaaacag cccaccaccc aaaagcaagg     1500

atgaagtggc acagccactg aacctatcag ctaaacccaa gacctctgat ggcaaatcac     1560

ccacatcacc cacctctccc catatgccag ctctgagaat aaacagtggg gcaggccccc     1620

tcaaagcctc tgtcccagca gcgttagcta gtccttcagc cagagttagc acaataggtt     1680

acttaaatga ccatgatgct gtcaccaagg caatccaaga agctcggcaa atgaaggagc     1740

aactccgacg ggaacaacag gtgcttgatg ggaaggtggc tgttgtgaat agtctgggtc     1800

tcaataactg ccgaacagaa aaggaaaaaa caacactgga gagtctgact cagcaactgg     1860

cagttaaaca gaatgaagaa ggaaaattta gccatgcaat gatggatttc aatctgagtg     1920

gagattctga tggaagtgct ggagtctcag agtcaagaat ttatagggaa tcccgagggc     1980

gtggtagcaa tgaaccccac ataaagcgtc caatgaatgc cttcatggtg tgggctaaag     2040

atgaacggag aaagatcctt caagcctttc ctgacatgca caactccaac atcagcaaga     2100

tattgggatc tcgctggaaa gctatgacaa acctagagaa acagccatat tatgaggagc     2160

aagcccgtct cagcaagcag cacctggaga agtaccctga ctataagtac aagcccaggc     2220

caaagcgcac ctgcctggtg gatggcaaaa agctgcgcat tggtgaatac aaggcaatca     2280

tgcgcaacag gcggcaggaa atgcggcagt acttcaatgt tgggcaacaa gcacagatcc     2340

ccattgccac tgctggtgtt gtgtaccctg gagccatcgc catggctggg atgccctccc     2400

ctcacctgcc ctcggagcac tcaagcgtgt ctagcagccc agagcctggg atgcctgtta     2460

tccagagcac ttacggtgtg aaaggagagg agccacatat caaagaagag atacaggccg     2520

aggacatcaa tggagaaatt tatgatgagt acgacgagga agaggatgat ccagatgtag     2580

attatgggag tgacagtgaa aaccatattg caggacaagc caactgataa gggtcaaaag     2640

attgttgtga ccttaggact taaagaagcc ctaactggtt catccttacc agtggccaag     2700

cacattaact ttctcataca ctgactgtta ctttaactgt tagtcttaaa tagttgggac     2760

atcagctgac taatagacct cagcctcaaa aggcttggaa agaaaaaaca aatacaacaa     2820

gcaaacaaca atatcaacaa caagagattg aaataagcta tgggtaaaat aatgccagta     2880

attcagctgc tacatccaag cactgaagtc ttacccgtca actttttttt ttttttaaat     2940

aaactttatg gctgtttgtt ctacaatgtt ctagaaattc tcactcaggt acacagtgcc     3000

aacaagtggc ttgtgaatgt gttttgttgt tttgtgctac aatttttaaa aagaaaaaag     3060

ttttgttttg ttttttgggg tttctgggtt ttttcctttt ctttttcttt cctttcattt     3120

tttttctttg taatgcacct gacagaaaaa aaagaaaaat gaatttctct ttacttctct     3180

ccaccttctc catctctcta ctttaaagat ggaagtctgt gcatgagggg aaagagggaa     3240

aaagagcctg tttttaactt ccttgctatc caccacaaaa taagcaatta ttttctttag     3300

aggactttat ctattgcaca ccacactaca tctttgagca agtgccaaat ttgtactgaa     3360

gtgttgacca agttcatttt ttctctttac tttttccttt tccttcttaa gttaggacag     3420

tgttaaatct tagacaatcc cttgaaaaac ctgaaatacc agcagctggt gagatttgac     3480

tttttttttt aatggaaact gtaggtgctg ttctcaggtg aaaagagaga gagagagaga     3540

gacataagaa atttagagaa aaatattttc tgatcttgga tttttgtgtg tatgtatgta     3600

tgtgattatg gtactaataa taggaataac gttggaccat tgtgagttaa acccacatct     3660

ggggatgaaa tcccacatcc tcccaagtga ctggtctaga aataatcttg accttgactt     3720

tgcacttcaa atgacaactt aaccaagtat agggctcaga aattatattt ttaaatgtct     3780

gattattatt ggatggatca ggtggccctg tgtaatagag gtgtgcatgt ataacatgga     3840

agctactagc aaactgctcc cagatgtcct ttctccctgg tcagttggtt ccattaacgt     3900

ttgctactta gtgatttttg tttttcctgt tgatattttg agcaaaacaa tcattgtttt     3960

cattgaatat atttggccat tttttcagac aaatagaatt agcttatttc ttcaacattc     4020

catcctttcc cgatcaggaa atgaaactga tgattttata aggtattttt cacccctcca     4080

tgaagtgagg tggaggcctt tagcatttca gaagtgtggg ccatatgtag ttcatgccat     4140

aaaaagtagg atttaattaa aagtcattgc agcccaataa aatggagcct ggctgcaccc     4200

agggatcctt gccactgctc ttcccttgct gtcagattaa tccactgaag tccaactttg     4260

gttcaagcag agtatttgca aagagcaaca actgaatgtg atgggactgc ttatgtagat     4320

tttgccagcc aaatgccaag gcagttgtag ggcctgtaca aataaatgca aaatcatttc     4380

aagtcaattg ccattatttg tattgaagta tcagatagat agtaaatact gcaactagta     4440

gcttgatgtg ctatagtttt cactccagtc atcattttcc tatctcaccc cccgaaacac     4500

caccctaaag ttggattttt acatataaat aaaaaaagaa tcccttttaa aaaaaaaaaa     4560

aaaaaa                                                                4566


<210>  2122
<211>  2620
<212>  DNA
<213>  homo sapiens

<400>  2122
gcgcacgtac acacgaaggg cctgctgact acatctgccg gaaagcatcg ggccaagcct       60

ttctccattt tgcggtctag gaagtagcag aggccccttc ctgtagggag ttgccatgga      120

gacgcggtgg ggcaccgacg gagttctaat gacggccgtg attggtgcag gatcctgcta      180

atctcaggaa ggcccgtaga gaagggcaga cactggcctc agatacctga cctggtaccc      240

tctatgaggc ctgcggtgct gggctcccca gaccgagcac ccccagaaga tgaggggcct      300

gtcatggtga agctagagga ctctgaggag gagggtgagg ctgccttatg ggacccaggc      360

cctgaagctg cacgcctgcg tttccggtgc ttccgctatg aggaggccac agggccccaa      420

gaggccctgg cccagctccg agagctgtgt cgccagtggc tgcgtccaga ggtacgctcc      480

aaggagcaga tgctggagct gttggtgctg gagcagttcc tgggcgcact gccccctgag      540

atccaggccc gtgtgcaggg gcagcggcca ggcagccccg aggaggctgc tgccctagta      600

gatgggctgc gccgggagcc gggcggaccc cggagatggg tcacagtcca ggtgcagggc      660

caggaggtcc tatcagagaa gatggagccc tccagtttcc agcccctacc tgaaactgag      720

cctccaactc cagagcctgg gcccaagaca cctcctagga ctatgcagga atcaccactg      780

ggcctgcagg tgaaagagga gtcagaggtt acagaggact cagatttcct ggagtctggg      840

cctctagctg ccacccagga gtctgtaccc accctcctgc ctgaggaggc ccagagatgt      900

gggaccgtgc tggaccagat ctttccccac agcaagactg ggcctgaggg tccctcatgg      960

agggagcacc ccagggccct gtggcatgag gaagctgggg gcatcttctc cccagggttc     1020

gcgctgcagc taggcagcat ctccgcaggt ccaggtagtg taagccctca cctccacgtc     1080

ccctgggacc tcggcatggc tggcctttct ggccagatcc aatcaccctc ccgcgaaggt     1140

ggctttgcgc atgcgcttct gctccccagc gatctgagga gtgaacagga ccccacggac     1200

gaggatccct gccggggtgt gggccctgct ctgatcacca cccgctggcg ctcccccagg     1260

ggccggagcc ggggccgccc cagcactggg ggcggggtgg ttaggggcgg ccgttgcgat     1320

gtatgtggca aggtgttcag ccaacgcagc aacctgctga ggcaccagaa gatccacacg     1380

ggtgagcgac cattcgtgtg cagcgagtgc ggccgcagct tcagccgcag ctcgcacctg     1440

ctgcgccacc agcttacgca caccgaggag cggccgttcg tgtgcggcga ctgtggccag     1500

ggcttcgtgc gcagcgcgcg cctggaagag catcggagag tgcacacggg cgaacagcct     1560

ttccgttgcg ctgagtgcgg ccagagcttc cggcagcgct ccaatctgct gcagcaccag     1620

cgcatccacg gcgatccccc gggccctggc gctaagcccc cggcccctcc tggtgcgccc     1680

gagcctcccg gcccctttcc gtgcagcgag tgccgcgaga gcttcgcgcg gcgcgccgtg     1740

ctgctggagc accaggcggt acacacgggc gacaagtcct ttggctgcgt cgagtgcggc     1800

gagcgcttcg gccgccgctc agtgctgctg cagcaccggc gcgtgcacag tggcgagcgg     1860

cccttcgcct gtgccgagtg cggccagagc ttccggcagc gctccaacct gacgcagcac     1920

cggcgcatcc acaccgggga gcggcccttc gcctgcgccg agtgtggcaa ggccttccgc     1980

cagcggccta cgctcacgca gcatctccgc gtacacacgg gcgagaaacc ctttgcctgc     2040

cccgagtgtg gccagcgctt cagccagcgc ctcaagctca cgcgtcatca gaggacacac     2100

accggcgaaa agccctacca ctgcggtgag tgcggcctgg gcttcacgca ggtctcgcgg     2160

ctcaccgagc accagcgcat ccacacgggc gaacggccct tcgcctgccc cgagtgcggc     2220

cagagctttc ggcagcacgc caacctcacc cagcaccggc gcatccacac gggtgaacgg     2280

ccctacgcat gccctgagtg tggcaaggcc ttccgccagc ggcccacgct cacgcagcat     2340

ctgcgcaccc accgacgaga gaagcccttc gcctgccagg actgtggccg ccgcttccac     2400

cagagcacca agctcattca gcaccagcgc gtccacagcg ccgagtagct ccagccggga     2460

cgcactgtgt ccgccatggt cagaacacct acctcccctg gttattgtga ggctggcgat     2520

tacataagta taagcaggtc cgcccagggc ttggctactg taggtgtcca ataaacagta     2580

gatggaaact gggtctccac ccaaaaaaaa aaaaaaaaaa                           2620


<210>  2123
<211>  2938
<212>  DNA
<213>  homo sapiens

<400>  2123
gcgcacgtac acacgaaggg cctgctgact acatctgccg gaaagcatcg ggccaagcct       60

ttctccattt tgcggtctag gaagtagcag aggccccttc ctgtagggag ttgccatgga      120

gacgcggtgg ggcaccgacg gagttctaat gacggccgtg attggtgcag gatcctgcta      180

atctcaggaa ggcccgtaga gaagtgagga aaacgtggtg gggggcatgc gcgatctggt      240

aggcggtgct gccgtctgtt gtacctgaga ggcttgcgca tgccgacgca cggattcgag      300

gcggggagca tgggaagaag cggccaggag tatgacctga tcattgcgac caccgctagg      360

ggaagggagg agagggtgta gaaacgggga cgagggtggg ggaagggcaa ggaggcgctc      420

gagctggtgc gcggagcatc ctgggagacg tagtccagcg ggagggggaa gtcgaagact      480

gcgcgtgctc aggagcgcgg agcggcccgc tgagcgcaga ggggcagaca ctggcctcag      540

atacctgacc tggtaccctc tatgaggcct gcggtgctgg gctccccaga ccgagcaccc      600

ccagaagatg aggggcctgt catggtgaag ctagaggact ctgaggagga gggtgaggct      660

gccttatggg acccaggccc tgaagctgca cgcctgcgtt tccggtgctt ccgctatgag      720

gaggccacag ggccccaaga ggccctggcc cagctccgag agctgtgtcg ccagtggctg      780

cgtccagagg tacgctccaa ggagcagatg ctggagctgt tggtgctgga gcagttcctg      840

ggcgcactgc cccctgagat ccaggcccgt gtgcaggggc agcggccagg cagccccgag      900

gaggctgctg ccctagtaga tgggctgcgc cgggagccgg gcggaccccg gagatgggtc      960

acagtccagg tgcagggcca ggaggtccta tcagagaaga tggagccctc cagtttccag     1020

cccctacctg aaactgagcc tccaactcca gagcctgggc ccaagacacc tcctaggact     1080

atgcaggaat caccactggg cctgcaggtg aaagaggagt cagaggttac agaggactca     1140

gatttcctgg agtctgggcc tctagctgcc acccaggagt ctgtacccac cctcctgcct     1200

gaggaggccc agagatgtgg gaccgtgctg gaccagatct ttccccacag caagactggg     1260

cctgagggtc cctcatggag ggagcacccc agggccctgt ggcatgagga agctgggggc     1320

atcttctccc cagggttcgc gctgcagcta ggcagcatct ccgcaggtcc aggtagtgta     1380

agccctcacc tccacgtccc ctgggacctc ggcatggctg gcctttctgg ccagatccaa     1440

tcaccctccc gcgaaggtgg ctttgcgcat gcgcttctgc tccccagcga tctgaggagt     1500

gaacaggacc ccacggacga ggatccctgc cggggtgtgg gccctgctct gatcaccacc     1560

cgctggcgct cccccagggg ccggagccgg ggccgcccca gcactggggg cggggtggtt     1620

aggggcggcc gttgcgatgt atgtggcaag gtgttcagcc aacgcagcaa cctgctgagg     1680

caccagaaga tccacacggg tgagcgacca ttcgtgtgca gcgagtgcgg ccgcagcttc     1740

agccgcagct cgcacctgct gcgccaccag cttacgcaca ccgaggagcg gccgttcgtg     1800

tgcggcgact gtggccaggg cttcgtgcgc agcgcgcgcc tggaagagca tcggagagtg     1860

cacacgggcg aacagccttt ccgttgcgct gagtgcggcc agagcttccg gcagcgctcc     1920

aatctgctgc agcaccagcg catccacggc gatcccccgg gccctggcgc taagcccccg     1980

gcccctcctg gtgcgcccga gcctcccggc ccctttccgt gcagcgagtg ccgcgagagc     2040

ttcgcgcggc gcgccgtgct gctggagcac caggcggtac acacgggcga caagtccttt     2100

ggctgcgtcg agtgcggcga gcgcttcggc cgccgctcag tgctgctgca gcaccggcgc     2160

gtgcacagtg gcgagcggcc cttcgcctgt gccgagtgcg gccagagctt ccggcagcgc     2220

tccaacctga cgcagcaccg gcgcatccac accggggagc ggcccttcgc ctgcgccgag     2280

tgtggcaagg ccttccgcca gcggcctacg ctcacgcagc atctccgcgt acacacgggc     2340

gagaaaccct ttgcctgccc cgagtgtggc cagcgcttca gccagcgcct caagctcacg     2400

cgtcatcaga ggacacacac cggcgaaaag ccctaccact gcggtgagtg cggcctgggc     2460

ttcacgcagg tctcgcggct caccgagcac cagcgcatcc acacgggcga acggcccttc     2520

gcctgccccg agtgcggcca gagctttcgg cagcacgcca acctcaccca gcaccggcgc     2580

atccacacgg gtgaacggcc ctacgcatgc cctgagtgtg gcaaggcctt ccgccagcgg     2640

cccacgctca cgcagcatct gcgcacccac cgacgagaga agcccttcgc ctgccaggac     2700

tgtggccgcc gcttccacca gagcaccaag ctcattcagc accagcgcgt ccacagcgcc     2760

gagtagctcc agccgggacg cactgtgtcc gccatggtca gaacacctac ctcccctggt     2820

tattgtgagg ctggcgatta cataagtata agcaggtccg cccagggctt ggctactgta     2880

ggtgtccaat aaacagtaga tggaaactgg gtctccaccc aaaaaaaaaa aaaaaaaa       2938


<210>  2124
<211>  4946
<212>  DNA
<213>  homo sapiens

<400>  2124
cgggatgggg gagctccagg gcacggcgtc agcggattca cggagaagga gaaaagcccc       60

actgccgtgc agaagcctag gcccgggtga gacgcctgcg aaggctgcca gcagcggaag      120

agaaggggcg tcctccgtgc tgcgcagcac tcgcccgcgg taggtgggcg cggagctcag      180

agctgggagc caaacgcaaa cgctggcgag aagccccagc cccctccggc agcccactcg      240

ctgcggggag gggtttctca cgcccccagc tcctgggaga ctgcaccgga ggtcggaagt      300

aagccgggcg aggatgaatc atcccgccta actcctcctt cccggtcccc tagcctccgc      360

acgccggccc ccttcagaga tcttgcagcc gcgagcgaag actgccctat cctcagactc      420

taccgaaccc cctgtggcct gcggagacga ggagacggac gggtctggtg gccaatgaga      480

gcttcgatct cttgcccccc gcccaatggg ccgctgctca tgggccgggg cgggactagg      540

agggcaggta ggggcggtcc gggctggcgc gcggcgcggc ggctacgcgg ctgcggctca      600

cagagctagc gcctctctgg gtgtccgtgc cagtgctgcg cgggaaggca ccaccaccac      660

agccgccgcc gctggccagg gtgctggaca agacgggccc gtcggccacc tcgccagctc      720

aggcacccgc tgcagccgtc gctgtctcct cccagaccgg tccccatgga ggagatggaa      780

gaggagttga aatgccccgt gtgcggctcc ttctatcggg agcccatcat cctgccctgc      840

tctcacaatt tgtgtcaggc gtgcgcccgc aacatcctgg tgcagacccc agagtctgaa      900

tccccccaga gccatcgggc cgcgggctcc ggggtctccg actatgacta tctggacctg      960

gacaagatga gcctatacag cgaggcggac agcggctatg gctcctacgg ggggttcgcc     1020

agcgccccca ctaccccgtg ccagaagtcc cccaacggcg tccgcgtgtt tcccccggct     1080

atgccgccac cggccaccca cttgtcaccg gccctggccc cggtgccccg caactcctgt     1140

atcacctgcc cccagtgtca ccgcagcctc atcctggatg accgggggct ccgcggcttc     1200

cccaagaatc gcgtactgga aggggtaatt gaccgctacc agcagagcaa agccgcggcc     1260

ctcaagtgcc agctctgcga gaaggcgccc aaggaagcca ccgtcatgtg cgaacagtgc     1320

gatgtcttct actgcgatcc gtgccgcctg cgctgccacc cgccccgggg gcccctagcc     1380

aagcaccgcc tggtgccccc ggcccagggt cgtgtgagcc ggaggctgag cccacgcaag     1440

gtctccacct gcacagacca cgagctggag aaccacagca tgtactgcgt gcaatgcaag     1500

atgcccgtgt gctaccagtg cttggaggag ggcaaacact ccagccacga agtcaaggct     1560

ctgggggcca tgtggaaact acataagagc cagctctccc aggcgctgaa cggactgtca     1620

gacagggcca aagaagccaa ggagtttctg gtacagctgc gcaacatggt ccagcagatc     1680

caggagaaca gtgtggagtt tgaagcctgt ctggtggccc aatgtgatgc cctcatcgat     1740

gccctcaaca gaagaaaagc ccagctgctg gcccgcgtca acaaggagca tgagcacaag     1800

ctgaaggtgg ttcgagatca gatctctcac tgcacagtga aattgcgcca gaccacaggt     1860

ctcatggagt actgcttgga ggtgattaag gaaaatgatc ctagtggttt tttgcagatt     1920

tctgacgccc tcataagaag agtgcacctg actgaggatc agtggggtaa aggcacactc     1980

actccaagga tgaccacgga ctttgacttg agtctggaca acagccctct gctgcaatcc     2040

atccaccagc tggatttcgt gcaagtgaaa gcttcctctc cagtcccagc aacccctatc     2100

ctacagctgg aggaatgttg tacccacaac aacagcgcta cgttgtcctg gaaacagcca     2160

cctctgtcca cggtgcccgc cgatggatac attctggagc tggatgatgg caacggtggt     2220

caattccggg aggtgtatgt ggggaaggag acaatgtgca ctgtggatgg tcttcacttc     2280

aacagcacat acaacgctcg ggtcaaggcc ttcaacaaaa caggagtcag cccgtacagc     2340

aagaccctgg tcctccaaac gtctgaggtg gcctggtttg ctttcgaccc tggctcggcg     2400

cactcggaca tcatcctctc caatgacaac ctgacagtga cctgtagtag ctatgatgac     2460

cgggtggtgc tagggaagac tggcttctcc aagggcatcc actactggga gctcacggta     2520

gatcgctatg acaaccaccc tgatcctgcc tttggtgtgg ctcgcatgga cgtgatgaag     2580

gatgtgatgt taggaaaaga cgacaaagct tgggcaatgt atgtggacaa taaccggagc     2640

tggttcatgc acaacaactc gcacaccaac agaactgagg gagggatcac aaaaggggcc     2700

acaattgggg tcctcctcga cttaaataga aaaaacttga cattttttat caacgatgaa     2760

caacaaggtc ccatagcatt tgataacgtg gagggcctct tcttccctgc ggtcagcctg     2820

aacaggaacg tgcaggtcac gctgcacacc gggctcccag tccccgactt ctactccagc     2880

agagcatcaa tagcctaagg atgtgccgtg gaggcgccag ctgcctgttc ttacctccgc     2940

ctgcgagagc cacagcaagg agctcagcca gccgtggtgg ggtgcagagt tggcaggagt     3000

gggagaagga ggagagaaaa gctggtcctc tgcagtcttt acacccacag ctctgccctt     3060

ttccctttca acctctcctc cgctgtcatg cctgcttccg cttccatgtc caacaattct     3120

aaccaacaaa ggacctagac agcccaccaa gtcacttggt tcccactccc agattttgct     3180

tttatttaac ttaatttttt atgtaggtga gttatatttt ctttcttttc tgatcaggtt     3240

attggtgact tactggactg gcaccgccag gagaaaattc tcctgctaac tttttttctt     3300

aagctttctg tcaaacaatg aggttgtagg gggaggtagg gaagaatgag ctgaatttgt     3360

agcatacagc ttacctgcta gaatgttctt accctcttac ctctcctgta gcgttagctc     3420

tgcagagcta agctttggga gaatgaatct atcactgaga agttttacta ctcattgaag     3480

cacaaaaata tccgctacac aggttcacat cagggtagga tcgttaggat ggctctataa     3540

ttaggatagg ccagaaccct ggccactgta taaaattgga aagtctctaa gacacaggca     3600

aaccagggga cttaatgatt tggttcgttt atttaataaa agcttttaat tgagaaccta     3660

ctattgacca ggcactgttc aagacactag aacattatgt tctagacact gtggggacac     3720

agtggtgaac agacaggcat ggtctctgcc cttcggagct tatattccag taggagaaaa     3780

agcaaaaata aaataattat aaatggtcat atgtactaga aaggaaatgg gcaagggtca     3840

aagagactca tgggcaagat ctttcaggct tcctagaatg atgctaaaaa tccacacatt     3900

ctggccatag caccagaaat gtaccaactc aatgcctttt cagctgcact atttaattat     3960

ggtacctgct gccactcatc acagagccct tcttggtaga aatgatgtca gcattcttat     4020

ttgctgatgc tgctatgata ccacgcctta aaaattgaca gttgaaaaaa aaaagagtga     4080

ccagagggca aaggacccat tctcagtaat gggagatctt gagttgcagt ccacagcatt     4140

cacattctca ggataaacat gcttgtctcc atatatacta tctgtgcctg ttatgaatga     4200

aaaatccatc cactctgctg ccattcacag cctaattttc tggagtagtc caaacaatgt     4260

ttggaaaaac atgggactgt atgtcattac tatgactgat agcagaataa taatgcatct     4320

tacttctata tagagataga cttacatagg ttacccttga aattcattag tttgtcataa     4380

agttttagga aaggtaggac ccggaaagaa gttctaatta gttgtctaaa tatttttcag     4440

tgagccaaga aattcaccat gaaaaaacaa gaataacaaa tagaagggaa gagataggat     4500

gggaaagcta acaaattaaa gttttggcaa aaaggaatat atgtaaatag ctaattattt     4560

acttttgtgc ttactttatt tagattattt ctatcagtta caatcttttt ctagttaagt     4620

gtacctaatt tatggaatgg gtgctatcct gtttatgtgt gtcttggttt ttcttggcta     4680

cagaaaaact gttgcagggc aacactagtt tgatatttga tttactctcc aatgagactc     4740

aatggctggg ccgtggtaga ctcatagttc ctcttgttct ttattaaatt catcctgcta     4800

attagatttc tagtgacttg taacatgtag tttacactga attgcaatta cagatgcata     4860

caactactat actagaaaaa attgtcattt ctgatgtgcc aataaatgat ttttatgaga     4920

gaataaaaaa aaaaaaaaaa aaaaaa                                          4946


<210>  2125
<211>  4393
<212>  DNA
<213>  homo sapiens

<400>  2125
cgggatgggg gagctccagg gcacggcgtc agcggattca cggagaagga gaaaagcccc       60

actgccgtgc agaagcctag gcccgggtga gacgcctgcg aaggctgcca gcagcggaag      120

agaaggggcg tcctccgtgc tgcgcagcac tcgcccgcgg taggtgggcg cggagctcag      180

agctgggagc caaacgcaaa cgctggcgag aagccccagc cccctccggc agcccactcg      240

ctgcggggag gggtttctca cgcccccagc tcctgggaga ctgcaccgga ggtcggaagt      300

aagccgggcg aggatgaatc atcccgccta actcctcctt cccggtcccc tagcctccgc      360

acgccggccc ccttcagaga tcttgcagcc gcgagcgaag actgccctat cctcagactc      420

taccgaaccc cctgtggcct gcggagacga ggagacggac gggtctggtg gccaatgaga      480

gcttcgatct cttgcccccc gcccaatggg ccgctgctca tgggccgggg cgggactagg      540

agggcaggta ggggcggtcc gggctggcgc gcggcgcggc ggctacgcgg ctgcggctca      600

cagagctagc gcctctctgg gtgtccgtgc cagtgctgcg cgggaaggca ccaccaccac      660

agccgccgcc gctggccagg gtgctggaca agacgggccc gtcggccacc tcgccagctc      720

aggcacccgc tgcagccgtc gctgtctcct cccagaccgg tccccatgga ggagatggaa      780

gaggagttga aatgccccgt gtgcggctcc ttctatcggg agcccatcat cctgccctgc      840

tctcacaatt tgtgtcaggc gtgcgcccgc aacatcctgg tgcagacccc agagtctgaa      900

tccccccaga gccatcgggc cgcgggctcc ggggtctccg actatgacta tctggacctg      960

gacaagatga gcctatacag cgaggcggac agcggctatg gctcctacgg ggggttcgcc     1020

agcgccccca ctaccccgtg ccagaagtcc cccaacggcg tccgcgtgtt tcccccggct     1080

atgccgccac cggccaccca cttgtcaccg gccctggccc cggtgccccg caactcctgt     1140

atcacctgcc cccagtgtca ccgcagcctc atcctggatg accgggggct ccgcggcttc     1200

cccaagaatc gcgtactgga aggggtaatt gaccgctacc agcagagcaa agccgcggcc     1260

ctcaagtgcc agctctgcga gaaggcgccc aaggaagcca ccgtcatgtg cgaacagtgc     1320

gatgtcttct actgcgatcc gtgccgcctg cgctgccacc cgccccgggg gcccctagcc     1380

aagcaccgcc tggtgccccc ggcccagggt cgtgtgagcc ggaggctgag cccacgcaag     1440

gtctccacct gcacagacca cgagctggag aaccacagca tgtactgcgt gcaatgcaag     1500

atgcccgtgt gctaccagtg cttggaggag ggcaaacact ccagccacga agtcaaggct     1560

ctgggggcca tgtggaaact acataagagc cagctctccc aggcgctgaa cggactgtca     1620

gacagggcca aagaagccaa ggagtttctg gtacagctgc gcaacatggt ccagcagatc     1680

caggagaaca gtgtggagtt tgaagcctgt ctggtggccc aatgtgatgc cctcatcgat     1740

gccctcaaca gaagaaaagc ccagctgctg gcccgcgtca acaaggagca tgagcacaag     1800

ctgaaggtgg ttcgagatca gatctctcac tgcacagtga aattgcgcca gaccacaggt     1860

ctcatggagt actgcttgga ggtgattaag gaaaatgatc ctagtggttt tttgcagatt     1920

tctgacgccc tcataagaag agtgcacctg actgaggatc agtggggtaa aggcacactc     1980

actccaagga tgaccacgga ctttgacttg agtctggaca acagccctct gctgcaatcc     2040

atccaccagc tggatttcgt gcaagtgaaa gcttcctctc cagtcccagc aacccctatc     2100

ctacagctgg aggaatgttg tacccacaac aacagcgcta cgttgtcctg gaaacagcca     2160

cctctgtcca cggtgcccgc cgatggatac attctggagc tggatgatgg caacggtggt     2220

caattccggg aggtgtatgt ggggaaggag acaatgtgca ctgtggatgg tcttcacttc     2280

aacagcacat acaacgctcg ggtcaaggcc ttcaacaaaa caggagtcag cccgtacagc     2340

aagaccctgg tcctccaaac gtctgagggt aaggcccttc agcagtatcc ctcagagcga     2400

gaactgcgtg gcatctaaag tggctggcaa gcccggaggt aaccccacca ctgcccacat     2460

tcctgaagtg tttccatgac ttgctctgca ttctgcacag agccgctgtt cctctcctgc     2520

ctttagagag cctatggtat gtggatgtga tcaaaccaaa gattccacat cggcagttcc     2580

aatggcttgg gccggcggct tcctttgata acaatctaaa taagctgcag ttgaagaagc     2640

tgaaaaatga aggcctgaat gtgcccctgg tgtgtaagac aaatgtatct aggctctaga     2700

gcaggctccc attctccacc gatacacatc atgtgccagt tttgcccaga tgattctaaa     2760

ttactctgta gtacttgctt gttctgaggg tgggacctag gttctttcca gtcgtggatt     2820

tgtatgactg aatgtgtttc aaatgggtgg tggggtgcta gagctgttta gagagggcct     2880

gttggctgct cctggcttac ccacttagac tgcctccgtt tcatacccaa agcggaggcc     2940

gtcagcacca ggattgagac ttcctgtggg caccaaacag gaagagacca gcaacttcgc     3000

attacccgcc attttcatct ttgccagtcc cttcagtctt ggctaggcta ccgagagcca     3060

ccatacaagg ttcatctcta gagaattttt gcttcttagc tatactttaa atattttggt     3120

catcaaagac aagtaatgtg tctcagatga gaggcttgaa tttgatggcc agatataacc     3180

tctgaggctt ttaacatttt cattttaaga gtaagcaaga cacatgaaat taaacctaca     3240

aggaggtatt tgtggctggt gccaaagcat tctgacactt tggggtgtca ttttaatcaa     3300

agaaatcacc cccccacctc accgggattc tccataactt ccctctgcag aactaattat     3360

gttgattttg ttcaagttca agatgttagc taaaagaact atggtggtgt tttttttccc     3420

acttcccaca aacctcaaca tgtgccagtc accctaaaat gcttcacatg gttaaaaaca     3480

agcacaattt tgaatcctac agcaaggatg aaaggcccct agccgtgaaa acagtgcttt     3540

ggggagcagt tgtcagtcta agtgatgcta ttccaagaga aggatatgct gagggaaaat     3600

gcccacatga cctgttccca tttggagtac agtgatgtgg tagctacagc ttcccccaga     3660

attatcattt tagcaccttc tctcagggat gacctatcag tttgagagca gttgcctctt     3720

ttctcaaaat accatactaa ctgctaaagc cctccaagag tctttcctag atgcaacgca     3780

gaaggccctt gctggtgatg gcctcatttc ccatgtgtgt acaaggtggt ttgattgaag     3840

agtgaagtgc atgcctgcag agcagagaga aatttgtagc aatgttgcta atatgtgtta     3900

tcagatctgc gggaaaacta tttctattca taatacatca tgggaatcat actattctgg     3960

taaaaatcag ttattagcat aacagcctga gcacttatgt ctctcgtttc atcctgcagg     4020

aggatgtagc gcctcagttt attttaatgt tcataagatt atggtgtcta atttaataaa     4080

ttacaggatt ggaactgcga tccttggtac cacagtcaca gaactggggg tcattttcta     4140

gatgaaacaa acggaacaag ttctcttcca acaaagaaac tgtactgtag aaattaattt     4200

cctccatgaa ttttatatat tgtgtacaaa tataaggtat gtatctgaat acaaagaaaa     4260

gcctatcatc atatagatat cagtattctc tgttactgca cagaagtaat tttctcatga     4320

tgaaataaag ttcacacaca tactttctcc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     4380

aaaaaaaaaa aaa                                                        4393


<210>  2126
<211>  4342
<212>  DNA
<213>  homo sapiens

<400>  2126
gatcaatact gaggccgcgt ccgaccccct tgagccgaga tcccccccca gcccagcccc       60

caccccaccc cccgcacacg ccccaccccc cccacgaccc agcctcatac cgcaccagct      120

gaggcaccca agaggattac cccctggggc cctctcccgc cccccaaaaa agagaagatc      180

ccctctcctg gcccatccct tcccttcttc cctcccccct ccccccgaac tttccctctc      240

gcatgctttt cccctgcacc acggatcgcc tctcggatgc cgcttgcctg gaagctgcgt      300

taggagcgag cggcggcggt ggcggcggtg gcggcggcgg cggcagctcg ggagtgctat      360

gaccggcaaa ctcgccgaga agctgccggt gaccatgagc agtttgctaa accaactgcc      420

tgacaatctg taccccgagg agatccccag cgcgctcaac ctcttctccg gcagcagcga      480

ctcggtagtc cattacaatc agatggctac agagaatgta atggacatcg gtctgaccaa      540

cgagaagccc aacccggaac tctcttactc cggctccttc cagccagccc ccggcaacaa      600

gaccgtgacc tacttgggaa agttcgcctt cgactcccct tccaactggt gccaggacaa      660

catcattagc ctcatgagcg ccggcatctt gggggtgccc ccggcttcag gggcgctcag      720

cacgcagacg tccacggcca gcatggtgca gccaccgcag ggtgacgtgg aggccatgta      780

tcccgcgcta cccccctact ccaactgcgg cgacctctac tcagagcccg tgtctttcca      840

cgacccccag ggcaatcccg ggctcgccta ttccccccag gattaccaat cggccaagcc      900

ggcgttggac agcaatctct tccccatgat tcctgactac aacctctacc accaccccaa      960

cgacatgggc tccattccgg agcacaagcc cttccagggc atggacccca tccgggtcaa     1020

cccgccccct attacccctc tggagaccat caaggcattc aaagacaagc agatccaccc     1080

gggctttggc agcctgcccc agccgccgct caccctcaag cccatccggc cccgcaagta     1140

ccccaaccgg cctagcaaga caccgctcca cgaacggccc cacgcgtgcc cggccgaggg     1200

ctgcgaccgc cgtttcagcc gttcggacga gctgacccgg cacctgcgca tccacacggg     1260

ccacaagccc ttccagtgcc ggatctgcat gcggagcttc agccgcagcg accacctcac     1320

cactcacatc cgcactcata cgggcgagaa gccctttgcc tgcgagttct gcgggcgcaa     1380

gtttgcgcgc agcgacgagc gcaagcgcca cgccaagatc cacctcaagc aaaaggagaa     1440

gaaggcggag aagggcggtg caccctctgc atcctcggcg ccccccgtgt cgctggcccc     1500

cgtggtcacc acctgcgcct gaggatcggg cccccagatc cccacttttc ccctccagtg     1560

cctcccggct gctagcctga aagcagcggg aaagccagcc acggaggcgt aggggccgcg     1620

ccctggcctc tccatggacg tgcggcccct tgcttcccct tcgatgcccc cggttcccaa     1680

cctttcacgc cggccagcgg tcaggggcca gggctggagg cgccttcccc tcgcggtccc     1740

ccacttagcc aaggcgtggg ggcggaaagg tggcgtctag cccgctttgt tcagttcgga     1800

tcgccttgat ccaggggccg ccgggccgcg ccaaggacct gcaagggact gaaggcggag     1860

cccatccaac cctcgcccga cccaaacacc tcattgtttc ccccacgtct ccctctatac     1920

cccctcgaag actcgagagg gggagggggt aaggagcgca ccaaagcgca gagcttgctg     1980

cccgccgcac gcacgcgcgc ctgcgtgcgg ggatgcgcgc gagtgtgtgc gtgctcgcgt     2040

gtgtgtgtat gtgtgtgtgt gagtgtgtgt gtgtgcgcgc gcgcaagcgt gtgtgtttaa     2100

gactcttgag ctgaactggg ctgtgtttac cccaaactct tccccacctc gggtccccaa     2160

gccgctggga gatgtcccat gctgggggtc cgcacgtggc tggaggaggt ggtcttccat     2220

ccgctctgaa atcatgtttc ttagagaaat gcctcggatg ccgccgacgc ggtgctgctg     2280

ccgccgcttc gggtttggcc cctcagaacc cctccttttc tgagcgcttc cctcttaggc     2340

ctcagggcag tttgatctgt ggggagaaag agcagccatc gctgagcctg ccttttaaaa     2400

tatatgtgta tttccttagc cccactctaa gaaatctatg ttcctgagtt tgccccctgc     2460

cctcccactc cttccccttc tcccctctaa accttctccc atctctttca aaatcttttc     2520

ccagaaaggc aggcttcaac cagccactcc agctttgtgt cttctctcaa ttacatagca     2580

atttctcctt cccaccatca tggggaagct ggctctgctt ttgccctttg tcatcaccaa     2640

cacaacagat agaatttaaa tataagtata tggtgtgcgt gtgtatgtat gtgtatgtat     2700

atgcatgcat gtgtataaag atgcacatgc gtacatatac ataacataca cacaatatgt     2760

attcctagca aaataaaatc tctaaggtac ttggttatcc agtgcagtgc accggaataa     2820

agagaatttg taggcgtata cagctttaaa tgatttattt tttatgaaaa tgttaactga     2880

tgagattata tctacatacg tgtgttatgt gtgtggatat agatgcacac atatctgtac     2940

atatacatgt gagtgtacat atatacacat atacacatct atgtatggat atgtgtgtat     3000

acacatatac acatctctgt ccaaaatttc ctcaaagata tggggatttt ttcatgaatc     3060

catgtggatg aatgaggtgt ctcctttcca tacccagtct caccttctcc ccaccctacc     3120

tcacctcttc tcaggcaccc ctcttcccca gctgtcctgc cagcccttct cgtacagggt     3180

ggctcctttg aagtggagta atagggaagg ttgctctctg ccacagcttg cagcatggtc     3240

ttgactgaat gtactgttcc tgttagcgtt acttctcctg tggtcagtaa gttgcccaga     3300

gagaaggaac aaaggtctgg agtttacaga atgtctgttt ttaaagtcac tttatgcgtt     3360

ttccactttt ttctttttta agaaaaagaa gtaccatttt tgttttgttt tgttttgatt     3420

tttggtggtg gataaataat actaaaagga ctctagtgga aaggggggat atcgaagagc     3480

agggggttgt gaatttccag gtacttggac tttttgtaga aggagagaga agaagatgaa     3540

gtttgccagg agggcccata ttttttcagc tgaagggtaa aatctttctt tgcagagaca     3600

gtattttgct gaatactttt tataatgtga tgattattaa aaaagcaaaa attttggtca     3660

cttccaagct agaaggagga atcagatacc ctttaatatt ttttcctcgc tccttctggt     3720

atatgcatgt cactgcatga taattgagtt ttcctttgtt ttaataaaac tgttctcaga     3780

cattaagcta aactaagaga aaaataactt tgttgccaaa aggttgtgct atccagattt     3840

tttatatgtc tgcatgttta aaaaaaaaaa gcaacaaaag aaaatgcact ctaacttatg     3900

tgaactgaga gaaaaaaatc aggttttaaa caggaaaacc tatggggaat gatatttttt     3960

gaaagacttt tgtataaagt tgagtactta gaaaaaagac aaaccagatg taatatattt     4020

tgtggatgtt tttatttctt ggatttatag taccttatac taaggttaaa aaaatatgct     4080

tgatattgtg aaaaggtgaa attcttcacc aacatttcat ttgctccttt gtcatattgt     4140

aatgccaata taatatagtt aatgaaaaca gcatttttaa aaaccgaaat attgaaatgg     4200

tgtaatgttg taccatttgc actgtgagca aatgctaata cagtaaatat attgtgtttg     4260

ctgacaatca gccggcctat aaatctcctt attttatttc ttgtttttat agcataaagc     4320

tttagtttgg cctgaaaaaa aa                                              4342


<210>  2127
<211>  2265
<212>  DNA
<213>  homo sapiens

<400>  2127
acttccgcca ggcggggacc cgatggccac ggtggctctg ggttgtcggg cctcgaaccg       60

ggtctccaga cgttgggccc ctccctccca gcgcgggaga ggcggggaag ggggcggggc      120

gggggagggg ccgcagcgct tttctccgga ggtcgcgcgc ccgagagccc gcgctgtccg      180

ccgccgctgc ctgagtcgac tctgcgccgc ccgccgcgat ggaggccgcc gcccagttct      240

tcgtcgagag cccggacgtg gtctacggcc ccgaggccat cgaggcgcaa tacgagtacc      300

ggacgacgcg cgtcagccgc gagggtggcg ttctcaagga ggccaactac tacggctcgc      360

tgactcaggc gggcaccgtg agcctgggcc tggacgccga gggccaggag gtgttcgtac      420

ccttcagcgc ggtgctgccc atggtggcgc ccaacgacct cgtgttcgat ggctgggaca      480

tctcgtcgct gaacctggcc gaggcgatgc ggcgcgcgaa ggtgctggac tgggggctgc      540

aggagcaact gtggccgcac atggaggccc tgcggccccg gccttctgtt tacatccccg      600

aattcatcgc ggccaaccag agcgcgcgcg cggacaacct catcccaggc tcgcgtgcgc      660

agcagctgga gcagatccgc agggacatcc gagacttccg gtctagcgcg gggctggaca      720

aagtcatagt gctgtggacg gcgaacacgg agcgcttctg tgaggtgatt ccaggcctca      780

acgacacagc cgagaacctg ctgcgcacca ttgagctcgg tctggaggtg tcgccctcca      840

cgctcttcgc cgtggccagc atcctggagg gctgtgcctt cctcaatggg tctccgcaga      900

acaccctggt gcccggagct cttgagctcg cgtggcagca ccgggttttt gtgggcggag      960

atgacttcaa gtcaggccag accaaagtca agtccgtgct tgtggacttc ctcattggct     1020

ccggcctcaa gaccatgtcc atcgtgagtt acaaccacct gggcaacaac gatggggaga     1080

acctatcggc gccattgcag ttccgctcta aggaggtgtc caagagcaac gtggtggacg     1140

acatggtgca gagcaaccca gtgctctata cgcccggcga agagcctgac cactgcgtgg     1200

tcatcaagta tgtgccgtac gtgggtgaca gcaagcgcgc gctggatgag tatacctcgg     1260

agctgatgct gggcggaacc aacacactgg tgctgcacaa cacgtgtgag gactcgctgc     1320

tggccgcacc catcatgctg gacctagcgc tgctgaccga gctgtgccag cgcgtgagct     1380

tctgcactga catggacccc gagccgcaga ccttccaccc cgtgctgtcc ctgctcagct     1440

tcctcttcaa ggcgccacta gtgccgcccg gcagcccggt ggtcaatgcg cttttccgcc     1500

agcgcagctg catcgagaac atcctcaggg cctgcgtggg gctcccgcca cagaaccaca     1560

tgctcctgga acacaaaatg gagcgcccag ggcccagcct caagcgagtt ggacccgtgg     1620

ctgccaccta ccctatgttg aacaagaaag gaccggtacc cgctgccacc aatggctgca     1680

ccggtgatgc caatgggcat ctgcaagagg agcccccaat gcccaccacc tgaggccccg     1740

gtcacacagt ttctcggctc ttcctccccg ctgcccccca cgaccctacc ttgaaggccc     1800

ccacaaataa aggcgctgcc actcagccct ccttccacct ggggttcttg gggcctgtga     1860

cctgactctg cctccctcta cttccccgac tcttgagcgc ccagcttcag tcccatcccc     1920

tctgcccatg gtcatcaccc caactcccag ggagagccca gaacctggag cctcgctctg     1980

cccccagttc tcaaaggtgg ggctagatgg gggcggggac ggaacaagac cacagggtgg     2040

agagtgtggt ggcagaaggc caaagaggga atctgagaca agctaccaaa aaccaaaacc     2100

agcttccatt tatttatggg ccccaccccc tgacgtcctg gggagagggg ccccccaaag     2160

agcctttctc tctgggacaa aatacaaatg gcaggaaggg tccatacaga aaagaacgtc     2220

tctgaggtcc ttgcgttttt aataaaatgg taagagtcaa aaaaa                     2265


<210>  2128
<211>  2427
<212>  DNA
<213>  homo sapiens

<400>  2128
acttccgcca ggcggggacc cgatggccac ggtggctctg ggttgtcggg cctcgaaccg       60

ggtctccaga cgttgggccc ctccctccca gcgcgggaga ggcggggaag ggggcggggc      120

gggggagggg ccgcagcgct tttctccgga ggtcgcgcgc ccgagagccc gcgctgtccg      180

ccgccgctgc ctgagtcgac tctgcgccgc ccgccgcgat ggaggccgcc gcccagttct      240

tcgtcgagag cccggacgtg gtctacggcc ccgaggccat cgaggcgcaa tacgagtacc      300

ggacgacgcg cgtcagccgc gagggtggcg ttctcaaggt gcaccccacg tccacgcgct      360

tcaccttccg gaccgcccgg caggtgcccc ggctcggggt catgcttgtc ggctggggcg      420

ggaacaacgg ctccacactc accgccgcgg tgctggccaa tcgactgcgt ttgtcctggc      480

ccacgcgcag cggccgcaag gaggccaact actacggctc gctgactcag gcgggcaccg      540

tgagcctggg cctggacgcc gagggccagg aggtgttcgt acccttcagc gcggtgctgc      600

ccatggtggc gcccaacgac ctcgtgttcg atggctggga catctcgtcg ctgaacctgg      660

ccgaggcgat gcggcgcgcg aaggtgctgg actgggggct gcaggagcaa ctgtggccgc      720

acatggaggc cctgcggccc cggccttctg tttacatccc cgaattcatc gcggccaacc      780

agagcgcgcg cgcggacaac ctcatcccag gctcgcgtgc gcagcagctg gagcagatcc      840

gcagggacat ccgagacttc cggtctagcg cggggctgga caaagtcata gtgctgtgga      900

cggcgaacac ggagcgcttc tgtgaggtga ttccaggcct caacgacaca gccgagaacc      960

tgctgcgcac cattgagctc ggtctggagg tgtcgccctc cacgctcttc gccgtggcca     1020

gcatcctgga gggctgtgcc ttcctcaatg ggtctccgca gaacaccctg gtgcccggag     1080

ctcttgagct cgcgtggcag caccgggttt ttgtgggcgg agatgacttc aagtcaggcc     1140

agaccaaagt caagtccgtg cttgtggact tcctcattgg ctccggcctc aagaccatgt     1200

ccatcgtgag ttacaaccac ctgggcaaca acgatgggga gaacctatcg gcgccattgc     1260

agttccgctc taaggaggtg tccaagagca acgtggtgga cgacatggtg cagagcaacc     1320

cagtgctcta tacgcccggc gaagagcctg accactgcgt ggtcatcaag tatgtgccgt     1380

acgtgggtga cagcaagcgc gcgctggatg agtatacctc ggagctgatg ctgggcggaa     1440

ccaacacact ggtgctgcac aacacgtgtg aggactcgct gctggccgca cccatcatgc     1500

tggacctagc gctgctgacc gagctgtgcc agcgcgtgag cttctgcact gacatggacc     1560

ccgagccgca gaccttccac cccgtgctgt ccctgctcag cttcctcttc aaggcgccac     1620

tagtgccgcc cggcagcccg gtggtcaatg cgcttttccg ccagcgcagc tgcatcgaga     1680

acatcctcag ggcctgcgtg gggctcccgc cacagaacca catgctcctg gaacacaaaa     1740

tggagcgccc agggcccagc ctcaagcgag ttggacccgt ggctgccacc taccctatgt     1800

tgaacaagaa aggaccggta cccgctgcca ccaatggctg caccggtgat gccaatgggc     1860

atctgcaaga ggagccccca atgcccacca cctgaggccc cggtcacaca gtttctcggc     1920

tcttcctccc cgctgccccc cacgacccta ccttgaaggc ccccacaaat aaaggcgctg     1980

ccactcagcc ctccttccac ctggggttct tggggcctgt gacctgactc tgcctccctc     2040

tacttccccg actcttgagc gcccagcttc agtcccatcc cctctgccca tggtcatcac     2100

cccaactccc agggagagcc cagaacctgg agcctcgctc tgcccccagt tctcaaaggt     2160

ggggctagat gggggcgggg acggaacaag accacagggt ggagagtgtg gtggcagaag     2220

gccaaagagg gaatctgaga caagctacca aaaaccaaaa ccagcttcca tttatttatg     2280

ggccccaccc cctgacgtcc tggggagagg ggccccccaa agagcctttc tctctgggac     2340

aaaatacaaa tggcaggaag ggtccataca gaaaagaacg tctctgaggt ccttgcgttt     2400

ttaataaaat ggtaagagtc aaaaaaa                                         2427


<210>  2129
<211>  8787
<212>  DNA
<213>  homo sapiens

<400>  2129
ggcgggtgct tctagggcgc tcccagagcc gcctccccct gttgctggca tcccgagctt       60

cctcccttgc cagccaggac gctgccgact tgtctttgcc cgctgctccg cagacggggc      120

tgcaaagctg caactaatgg tgttggcctc cctgcccacc tgtggaagca actgcgctga      180

ttgatgcgcc acagactttt ttcccctcga cctcgccggc gtcccctccc acagatccag      240

catcacccag tgaatgtaca ttagggtggt ttccccccca gcttcgggct ttgtttgggt      300

ttgattgtgt ttggctcttc gctaagctga tttatgcagc agaagcccca ccggctggag      360

agaaacaaaa gctcttttct ttgtcccgga gcaggctgcg gagcccttgc agagccctct      420

ctccagtcgc cgccggggcc cttggccgtc gaaggaggtg cttctcgcgg agaccgcggg      480

acccgccgtg ccgagccggg agggccgcag gggccctgag atgccgagcg gtgcccgggc      540

ccgcttacct gcaccgcttg ctccgagccg cggggtccgc ctgctaggcc tgcggaaaac      600

gtcctagcga cactcggccc gcgggccccg aggtgcgccc gggaggcgcg agcccgcgtc      660

cggaaggcag tcaggcggcg ggcgcggggc gggctgtttt gcattatgtg cggctcggcc      720

ctggcttttt ttaccgctgc atttgtctgc ctgcaaaacg accggcgagg tcccgcctcg      780

ttcctctggg cagcctgggt gttttcactt gttcttggac tgggccaagg tgaagacaat      840

agatgtgcat cttcaaatgc agcatcctgt gccaggtgcc ttgcgctggg tccagaatgt      900

ggatggtgtg ttcaagagga tttcatttca ggtggatcaa gaagtgaacg ttgtgatatt      960

gtttccaatt taataagcaa aggctgctca gttgattcaa tagaataccc atctgtgcat     1020

gttataatac ccactgaaaa tgaaattaat acccaggtga caccaggaga agtgtctatc     1080

cagctgcgtc caggagccga agctaatttt atgctgaaag ttcatcctct gaagaaatat     1140

cctgtggatc tttattatct tgttgatgtc tcagcatcaa tgcacaataa tatagaaaaa     1200

ttaaattccg ttggaaacga tttatctaga aaaatggcat ttttctcccg tgactttcgt     1260

cttggatttg gctcatacgt tgataaaaca gtttcaccat acattagcat ccaccccgaa     1320

aggattcata atcaatgcag tgactacaat ttagactgca tgcctcccca tggatacatc     1380

catgtgctgt ctttgacaga gaacatcact gagtttgaga aagcagttca tagacagaag     1440

atctctggaa acatagatac accagaagga ggttttgacg ccatgcttca ggcagctgtc     1500

tgtgaaagtc atatcggatg gcgaaaagag gctaaaagat tgctgctggt gatgacagat     1560

cagacgtctc atctcgctct tgatagcaaa ttggcaggca tagtggtgcc caatgacgga     1620

aactgtcatc tgaaaaacaa cgtctatgtc aaatcgacaa ccatggaaca cccctcacta     1680

ggccaacttt cagagaaatt aatagacaac aacattaatg tcatctttgc agttcaagga     1740

aaacaatttc attggtataa ggatcttcta cccctcttgc caggcaccat tgctggtgaa     1800

atagaatcaa aggctgcaaa cctcaataat ttggtagtgg aagcctatca gaagctcatt     1860

tcagaagtga aagttcaggt ggaaaaccag gtacaaggca tctattttaa cattaccgcc     1920

atctgtccag atgggtccag aaagccaggc atggaaggat gcagaaacgt gacgagcaat     1980

gatgaagttc ttttcaatgt aacagttaca atgaaaaaat gtgatgtcac aggaggaaaa     2040

aactatgcaa taatcaaacc tattggtttt aatgaaaccg ctaaaattca tatacacaga     2100

aactgcagct gtcagtgtga ggacaacaga ggacctaaag gaaagtgtgt agatgaaact     2160

tttctagatt ccaagtgttt ccagtgtgat gagaataaat gtcattttga tgaagatcag     2220

ttttcttctg agagttgcaa gtcacacaag gatcagcctg tttgcagtgg tcgaggagtt     2280

tgtgtttgtg ggaaatgttc atgtcacaaa attaagcttg gaaaagtgta tggaaaatac     2340

tgtgaaaagg atgacttttc ttgtccatat caccatggaa atctgtgtgc tgggcatgga     2400

gagtgtgaag caggcagatg ccaatgcttc agtggctggg aaggtgatcg atgccagtgc     2460

ccttcagcag cagcccagca ctgtgtcaat tcaaagggcc aagtgtgcag tggaagaggc     2520

acgtgtgtgt gtggaaggtg tgagtgcacc gatcccagga gcatcggccg cttctgtgaa     2580

cactgcccca cctgttatac agcctgcaag gaaaactgga attgtatgca atgccttcac     2640

cctcacaatt tgtctcaggc tatacttgat cagtgcaaaa cctcatgtgc tctcatggaa     2700

caacagcatt atgtcgacca aacttcagaa tgtttctcca gcccaagcta cttgagaata     2760

tttttcatca ttttcatagt tacattcttg attgggttgc ttaaagtcct gatcattaga     2820

caggtgatac tacaatggaa tagtaataaa attaagtcct catcagatta cagagtgtca     2880

gcctcaaaaa aggataagtt gattctgcaa agtgtttgca caagagcagt cacctaccga     2940

cgtgagaagc ctgaagaaat aaaaatggat atcagcaaat taaatgctca tgaaactttc     3000

aggtgcaact tctaaaaaaa gatttttaaa cacttaatgg gaaactggaa ttgttaataa     3060

ttgctcctaa agattataat tttaaaagtc acaggaggag acaaattgct cacggtcatg     3120

ccagttgctg gttgtacact cgaacgaaga ctgacaagta tcctcatcat gatgtgactc     3180

acatagctgc tgactttttc agagaaaaat gtgtcttact actgtttgag actagtgtcg     3240

ttgtagcact ttactgtaat atataactta tttagatcag catagaatgt agatcctctg     3300

aagagcactg attacacttt acaggtacct gttatcccta cgcttcccag agagaacaat     3360

gctgtgagag agtttagcat tgtgtcacta caagggtaca gtaatccctg cactggacat     3420

gtgaggaaaa aaataatctg gcaagtatat tctaaggttg ccaaacactt caacagttgg     3480

tggttgaata gacaagaaca gctagatgaa taaatgattc gtgtttcact ctttcaagag     3540

gtgaacagat acaaccttaa tcttaaaaga ttattgcttt ttaaagtgtg tagttttatg     3600

catgtgtgtt tatggtttgc ttatttttgc aagatggata ctaattccag cattctctcc     3660

tctttgcctt tatgttttgt tttctttttt acaggataag tttatgtatg tcacagatga     3720

ctggattaat taagtgctaa gttactactg ccataaaaaa ctaataatac aatgtcactt     3780

tatcagaata ctagttttaa aagctgaatg ttaatagggg acactgtaaa gtatcatcaa     3840

aacctgaata gcttcattgt gcacaagtgt ggagttttgt atcctcttac ctggtaaact     3900

gaagggattg tttggccatt tcatttatct tatcattaat tcacaagata gttagaaatt     3960

ctgcctcaag caaagtacca cattttgaat gttttcttag attttgattg caagtagata     4020

tcagcatttt ttaaatgaaa agctatatta tcttctccct tcaaggcagc ctaaggatgt     4080

tctttcccag aatcactcca acccttcttg ccagaattca taaaagtaca aaattggaga     4140

atagatgata tcttagaaat aagctttttt tttttttttt tttttttttg agacggagtt     4200

tcactcttgt cacccaggct gaagtgcaat ggcgcaatta gggttcactg caacctctgc     4260

ctcccgggtt caagcagttc tcctgcctca gcctcctgag tagctgggat tacaggcatc     4320

caccaccgtg cccagctaat ttttgtattt ttagtagaga cggggttttg ccatgttgga     4380

caggttgatc tcaaactcct gacctcaggt gatctaccct cctcggcctc ccagagtgtt     4440

gggattacag gcatgagcca ccatgccagg ctgctaattc tcctttttag tgagttaggg     4500

aactgagcct cagaaaactt aaacgatttc tcagaaaaca ctcaagtgat aaagtggcca     4560

cattggaaag gagtttttat cttctcattg tcaggccagt gttcattgca caatatcatg     4620

ctacctcttg aatctttaaa atattcaatt ggcaaatgtt tttcaatgtg atttactcat     4680

gtcttaagtg tatgaggaaa gttcaaagca aaatagaaag gaataattca aactgaattg     4740

tccataatca gcttccagtc tttcatgcta atcagcttct taagagactg aagtatggca     4800

tacctacagg ggaattcctt cgcaccatag cctgtatgaa cagtgttccc tggagttctc     4860

cagtgctcag cttgagacct tgatacacgg gccatgagcc ctgtcttccc caatggaaat     4920

ttatttacac ttaccttatc cctatggact tagtctgatt ttattggcta ggagtctaac     4980

agtcctgtgt ggatatacag ttttgcccat gacaacaaag gaatctatcc gaaatatctt     5040

tttttttata ataaacttcc aagatttgct gtcttccagc acttgagtta aagtactaga     5100

tactgcattt tgatgaagac taaccccatc tcatattcta ccctaaagag aactgaaaaa     5160

cctataataa gttgttctgg agccaataaa cacagcagct ctgttagatg tcctctacag     5220

ccaagcactt tcaatgctaa cttgaactgc atttccttcc tcaaatgaga gattgacata     5280

attcagtact gtgagtcact tgtataagaa acctttgatc actaaaaata atgtaaaaat     5340

tgggtttagt agcctaatac acataacgtt cttcttaaaa aggaaaatgg atggatgcct     5400

gacaaccctc caaaagaaaa aagtgtaaga tagccattaa gatgatgaca atttttgaaa     5460

tgaacattat gatatttatg aacaataaac aaatttccgt atggaatgaa ttatccaaaa     5520

agagtataac aaaatgaaat ccttaaaaat ccagagttta tatttttttt ataccctcac     5580

ttgtttgcac taactttata gtggaccaag gctgttacca taggaaggga caaacttcct     5640

tgtaggcaac tcagtgttag acgatgattg tggttatgct tgcaaagtct tgtgcttatc     5700

ttttttgttt ttacttaaaa agctaatttt taaagattgt agggcttgta ttttacttga     5760

ataattgata tcttcctgtg taatgatttg tgagatgaga attaatattt gactagttag     5820

aattaattaa atggtaaggg aacacagggt actcttaggt taaataatgt atgcaaatag     5880

agtctatttt caactaatat ggccacagga gccttttgag attcattgat attaaacaca     5940

attaatgaaa ttttaaattg ttaacagaat tgagaacttg aacaacactt ttagtactgc     6000

agcatttttg tgccctaaag tatgtaatga tttataaatg tgccatacat acactacaac     6060

ataacatttg ctttgttatg cattttattt ctctggggac accattgcac tgcagtgcac     6120

acgtatttat aaacatttgt tatatttttg gaaacttgct aatatttatt aagtcataga     6180

cttttctgga ggacttaaaa attcactaaa aatctgatta tgtcttaaat gttcagttta     6240

tctttggttt attaaaataa aaaaaaaatc taagattaaa cacagtagat atctctggag     6300

gcaattttcc aaaactcaac attaaaattt gtggatgcat gagatgcaat ccttcaaaga     6360

atgaatctga aatatatttt taatatttac ttaatatcca ctgaagatat ctttatgcaa     6420

gacaagagtc agccatcaga cactgaaata tattatgata gattatgaag aattttctct     6480

gtagaattat attcttcctg gaacctggta gagtagatta gactcaaagg ctttttcttc     6540

cttttcttac tcctgttttt tccactcact cttcccaaga gatttcctaa agcttcaagc     6600

ttaataagcc taatagtgaa aaataactga atttaatggt ataatgaagt tcttcatttc     6660

cagacatctt taattgatct taaagctcat ttgagtcttt gcccctgaac aaagacagac     6720

ccattaaaat ctaagaattc taaattttca caactgtttg agcttctttt cattttgaag     6780

gatttggaat atatatgttt tcataaaagt atcaagtgaa atatagttac atgggagctc     6840

aatcatgtgc agattgcatt ctgttatgtt gactcaatat ttaatttaca actatcctta     6900

tttatattga cctcaagaac tccattttat gcaatgcaga ccactgagat atagctaaca     6960

ttctttcaaa taattttcct tttcttttat aattcctcta tagcaaattt ttatgtataa     7020

ctgattatac atatccatat ttatatttca ttgattccaa gacatcactt tttcaattta     7080

acatctctga aattgtgaca tttcttgcaa ctgttggcac ttcagatgca gtgtttaaaa     7140

ttatgcttga ataaatatta cactaatcca actttaccta aatgtttatg catctaggca     7200

aattttgttt tcttataaag atttgagagc ccatttatga caaaatatga aggcgaaatt     7260

taaggacaac tgagtcacgc acaactcaac atggagccta actgattatc agctcagatc     7320

ccgcatatct tgagtttaca aaagctcttt caggtcccca tttatacttt acgtgagtgc     7380

gaatgatttc agcaaaccct aacttaacta acaagaatgg gtaggtatgt ctacgtttca     7440

ttaacaaatt tttattattt ttattctatt atatgagatc cttttatatt atcatctcac     7500

ttttaaacaa aattaactgg aaaaatatta catggaactg tcatagttag gttttgcagc     7560

atcttacatg tcttgtatca atggcaggag aaaaatatga taaaaacaat cagtgctgtg     7620

aaaaacaact ttcttctaga gtcctcttac tttttattct tctttatcat ttgtgggttt     7680

ttcccccttg gctctgatca ctttaacttc aagcttatgt aacgactgtt ataaaactgc     7740

atatttaaat tatttgaatt atatgaaata attgttcagc tatctgggca gctgttaatg     7800

taaacctgag agtaataaca ctactctttt atctacctgg aatacttttc tgcataaaat     7860

ttatctttgt aagctaactc tattaatcag gtttcttcta gcctctgcaa cctacttcag     7920

ttagaattgt ctaatactgc tctattaatc aggtttctag cctctacaac ctacttcagt     7980

taaaattgtc taatacagca atatttaaaa aaaaaacact gcaattgtca aggatggaaa     8040

atgtgtgatt tgtgtaaaca atttttacca actttacatt ttcctacaga taaatgtgaa     8100

attttgataa gaagtctacg caatgacaag tatggtacat aaattttatt aagaatattg     8160

agtataaagt actttaattc taaattataa gaaaatatac atttgcacat attaatatag     8220

aaattcattt tgtgtatatt taacatagct tttaaactat tttacattag ctacttcatt     8280

atggtttctt gaacttctga aaaaaattag aaatgtatta aacttatcag taacataaaa     8340

acttattttg tttcacctaa cgaatactgc gtttgtaaaa ataaatttaa tatagaatat     8400

atttttaaat taaatatttg aatataaaat agctctaaga aagaagcaaa ttatcactga     8460

acatatttct tattatttct ggctttgaat tatacgtaac ttaaattgtc ttaaatgata     8520

cagaatattg gagaatatga tactttcaca taatatacta tgaacctgtt catataactc     8580

tgattgacta ctaacttctg ttttatgtat ttattaaaga gctgacactg tagtttgtgg     8640

tgagatgttt atttttctaa cagagcttat aacagttagg acaaggcatt taattaatgc     8700

atcattctgt ttagtagtag gtgttaatca atatgaaatt ctctgtttta aaataaaaat     8760

gtaaaaatct aagaataaaa aaaaaaa                                         8787


<210>  2130
<211>  4007
<212>  DNA
<213>  homo sapiens

<400>  2130
gccccagccc agccccgcgg ggaggctccc gcagcccagg gacctcgagc tttccccgcg       60

ccgggcgctg cagccgggcc cctcccgcga ggcgcccggc agcctgaggc ttccttttgg      120

ttcccgcccc gggacgggag gctccgtccg ctccctggac agccggggtg ctccctcctt      180

ctccctcccg cgctctcctc ccccgtccgt ttgcagggag gtgctctcct cgggcggcgg      240

ggaaggcggg gctggcctgc cactcctcct gctatgatgc ctgggcagat cccggaccct      300

tcggtgacca caggctccct gccagggctt ggccccctga ccgggctccc cagctcggcc      360

ctgactgtgg aggagctgaa atacgctgac atccgcaacc tcggggccat gattgcaccc      420

ttgcacttcc tggaggtgaa actgggcaag aggccccagc ccgtgaaaag tgagctagat      480

gaggaagagg agcgaaggaa aaggcgccgg gagaagaaca aagtcgcagc agcccgatgc      540

cggaacaaga agaaggagcg cacggagttt ctgcagcggg aatccgagcg gctggaactc      600

atgaacgcag agctgaagac ccagattgag gagctgaagc aggagcggca gcagctcatc      660

ctgatgctga accgacaccg ccccacctgc atcgtccgga ccgacagtgt caagaccccc      720

gagtcagaag gcaacccact gctcgagcag ctcgagaaga agtgaccatg ggctgggagg      780

aggtggagga ggaggaagag gagaaggaaa agtgacgaag agagaggagg aggggggccc      840

cagatggccc ttcctttggt gcatgaaaaa ctgtacaatg aggttcagca cagccagcat      900

cagccgagct tttttgtgaa actcagatca gccacccagg aggaagagcg ggctgaggaa      960

acccagaggg accaagcgct gagaccaaag ttgaccctcg ggtagggttg tcctgcctgg     1020

ggccccactt gaaggaggca ggacagaggc accgaggcca gggagacgcc caacgaggca     1080

gccctgggct cttctctggc ctcttcacca gggcacccat ccaaggaacc tccgaacagc     1140

caggaaaagc catgagttgc aaccaaaacg cggctgagga tggaactcag aatgaaactg     1200

caacccacct gcccccagcc ctgcccctcg ccctgatgcg aagctggaga ggggcgtgct     1260

gcggggccct gatgccccca cccacctcgg tccagcgcgg ccctgcccag gaggcggcag     1320

ccgggcgcac cctcgccagc cctgctggag tttgctgtgg gcactgaggc gcgggcgccc     1380

ttccaaagca catactcacc gaatgtttac agactggctg tcctggcagg gctttcaact     1440

gcacatgttt tttatacttt cctttttttt ttttttttta atatttttta caaaaaaaaa     1500

gattttatac aagcaatata tatatggatt tctataatca ctcgatgtga tacagtataa     1560

atatgctatg gtttgtttgt tatgaacaga tagccaccag ttacggccgt tgtgtgtaac     1620

tcctaagtac tgtagtctct gggtgtcggg ggtggccagg gcgggggcgg ggtgcatttc     1680

catccttgta aacccttcat agtactcagt cctgtatcgc tcagtaaaca ttgctcttac     1740

ttacatagcc gccttgcgtg gtgtctgcct ggggaatggg tgcaaggccc tctcagggtc     1800

ggagactgtt tggagcctct gctataggcc tgttcatttt cacaacagct ctcctatttc     1860

acagatgagg aagctaaggc tcagagacat taagccacct gcagttacta ttttgagagc     1920

agtcagagtg ttcgctcact ctgcagatgt tttctgaggg cctgttgtgt gtgccaggcc     1980

ctgagaattc actggaggat gaaacagacc taagtcttgc ccttgtgggg cctccagtaa     2040

ggagtgaatc ctgtgcttgc tccataagtt gtctcatttc gtcttcatgg cagccttgcc     2100

agggaacagc acttgtcccc aattcacaga tggcgaatta gaggtccagg gaattaaact     2160

cgcagacacc atttgttgaa gacttatttt gtgacaagca gacatagtct cttcccttct     2220

cacaagagca caaactaggc acgattcttc tcattttaca gatggtttaa ctgaggctca     2280

gagaaggtaa gcgacttatc caaggtaacc cagctagcaa gggatagagc tggtgtttga     2340

actctccctc cagaggcctg tgactctcct cctgtcacca acccactatg attgtcctca     2400

tggttgaata ggaagcttat gaggccacag ttatagattt agtttctggg aaggctggat     2460

agagttccag gttgtcccat gatcacagag tgaaccaact accctggtca atgtgtgtct     2520

gacccaggga agggtgtgga tggcttctct gccccctcac ctcgacagct gaatccctgc     2580

cacccagggc cggagcagct cagtggcatt cactcagtgc ctgctgtgta cctggcactc     2640

ggcagttctc aaggcatgtc acgcatgagg aaggcgggag aggtgttttt agcttccttg     2700

tatactgaag cttgcaaagg ctacagttta cccaactaaa cttgactcct gcattctaat     2760

catgtgttct ttctcctcca tccctggact taggataact agttgctggt gatgacttcg     2820

tgtcaagaac agcagtgaac ctgggttgct tcccaaattg tggacgaggc cttctgggat     2880

gggcagaagt ggagaatggt gattaacaca cctgtgatcc ctccctcgct cactcctctc     2940

agtttccctc cacccaacac acttggtgtg gactcccctg caccccgccc tagaaacagg     3000

acctggtcct ctcactgtca gctgtggcag aaggttgtgg cagcgggttg ccttctgtct     3060

cgggggtctt gaggctgtcg gtccggacga tgcaggtgag gcagtgtcag ttctgcatca     3120

ggaacccctc gcgctgtaat cctttgatat ttttcaagcc atgagaaaaa tgaagtggac     3180

ttaccagggt ccctccagtg acctagtgga tgttcttaca ggactgccgt gtgccactgg     3240

ctgtggcttc cctggtcctg tgcttggcca ccgggagctg gcatctccaa aatagagcct     3300

ccttagcctg tgcaggtggg ctgtcttcca aagtcaccac accagtgact tgtgctgtgc     3360

ggagccttcc tcaccaggac cactggctgc tcctgtggct agaagtcaca attataggct     3420

tcattgcaag agccagcatt tgagtttctt ctgggcacct gccactgtgc atgtgtgacc     3480

tcaactgctt tgtgcaccct gactgggggg taggtgctag cgttccaaca ttacagatga     3540

gaaaaccgag gcacacagaa gaggtaacct gcccaaggtc acaggtgtta ggtggcagag     3600

ccaagatgtt attgtcagtc tgacttcagg tgcataaaac ctgaggctga gcctccccat     3660

gagaggaaaa atgtgtttgt ggtgtgacct cagttgccag ggaacttgtg caggaagccg     3720

ggagagatgg cacagaccca cctgtgctca cagtacatgt taagaattcc caagtctcag     3780

gcaaaccatc tccaagggtg ttcacagaag acacacctta aaggcaaacg ggttcatgat     3840

gtaatcttct attgactagc tgtgaacctc atttttctta tctgtgaagt gggaacagta     3900

ataatccaag tctttttatg gagttatcaa gatcaaaaaa ggaatggata tacaaagtgt     3960

tttgtgaaat aaaagctccc taaaatggta aaaaaaaaaa aaaaaaa                   4007


<210>  2131
<211>  3801
<212>  DNA
<213>  homo sapiens

<400>  2131
gcggccgcgg gaggagggcg cccaaggcgg cgggggaggt taaggctggc ctgccactcc       60

tcctgctatg atgcctgggc agatcccgga cccttcggtg accacaggct ccctgccagg      120

gcttggcccc ctgaccgggc tccccagctc ggccctgact gtggaggagc tgaaatacgc      180

tgacatccgc aacctcgggg ccatgattgc acccttgcac ttcctggagg tgaaactggg      240

caagaggccc cagcccgtga aaagtgagct agatgaggaa gaggagcgaa ggaaaaggcg      300

ccgggagaag aacaaagtcg cagcagcccg atgccggaac aagaagaagg agcgcacgga      360

gtttctgcag cgggaatccg agcggctgga actcatgaac gcagagctga agacccagat      420

tgaggagctg aagcaggagc ggcagcagct catcctgatg ctgaaccgac accgccccac      480

ctgcatcgtc cggaccgaca gtgtcaagac ccccgagtca gaaggcaacc cactgctcga      540

gcagctcgag aagaagtgac catgggctgg gaggaggtgg aggaggagga agaggagaag      600

gaaaagtgac gaagagagag gaggaggggg gccccagatg gcccttcctt tggtgcatga      660

aaaactgtac aatgaggttc agcacagcca gcatcagccg agcttttttg tgaaactcag      720

atcagccacc caggaggaag agcgggctga ggaaacccag agggaccaag cgctgagacc      780

aaagttgacc ctcgggtagg gttgtcctgc ctggggcccc acttgaagga ggcaggacag      840

aggcaccgag gccagggaga cgcccaacga ggcagccctg ggctcttctc tggcctcttc      900

accagggcac ccatccaagg aacctccgaa cagccaggaa aagccatgag ttgcaaccaa      960

aacgcggctg aggatggaac tcagaatgaa actgcaaccc acctgccccc agccctgccc     1020

ctcgccctga tgcgaagctg gagaggggcg tgctgcgggg ccctgatgcc cccacccacc     1080

tcggtccagc gcggccctgc ccaggaggcg gcagccgggc gcaccctcgc cagccctgct     1140

ggagtttgct gtgggcactg aggcgcgggc gcccttccaa agcacatact caccgaatgt     1200

ttacagactg gctgtcctgg cagggctttc aactgcacat gttttttata ctttcctttt     1260

tttttttttt tttaatattt tttacaaaaa aaaagatttt atacaagcaa tatatatatg     1320

gatttctata atcactcgat gtgatacagt ataaatatgc tatggtttgt ttgttatgaa     1380

cagatagcca ccagttacgg ccgttgtgtg taactcctaa gtactgtagt ctctgggtgt     1440

cgggggtggc cagggcgggg gcggggtgca tttccatcct tgtaaaccct tcatagtact     1500

cagtcctgta tcgctcagta aacattgctc ttacttacat agccgccttg cgtggtgtct     1560

gcctggggaa tgggtgcaag gccctctcag ggtcggagac tgtttggagc ctctgctata     1620

ggcctgttca ttttcacaac agctctccta tttcacagat gaggaagcta aggctcagag     1680

acattaagcc acctgcagtt actattttga gagcagtcag agtgttcgct cactctgcag     1740

atgttttctg agggcctgtt gtgtgtgcca ggccctgaga attcactgga ggatgaaaca     1800

gacctaagtc ttgcccttgt ggggcctcca gtaaggagtg aatcctgtgc ttgctccata     1860

agttgtctca tttcgtcttc atggcagcct tgccagggaa cagcacttgt ccccaattca     1920

cagatggcga attagaggtc cagggaatta aactcgcaga caccatttgt tgaagactta     1980

ttttgtgaca agcagacata gtctcttccc ttctcacaag agcacaaact aggcacgatt     2040

cttctcattt tacagatggt ttaactgagg ctcagagaag gtaagcgact tatccaaggt     2100

aacccagcta gcaagggata gagctggtgt ttgaactctc cctccagagg cctgtgactc     2160

tcctcctgtc accaacccac tatgattgtc ctcatggttg aataggaagc ttatgaggcc     2220

acagttatag atttagtttc tgggaaggct ggatagagtt ccaggttgtc ccatgatcac     2280

agagtgaacc aactaccctg gtcaatgtgt gtctgaccca gggaagggtg tggatggctt     2340

ctctgccccc tcacctcgac agctgaatcc ctgccaccca gggccggagc agctcagtgg     2400

cattcactca gtgcctgctg tgtacctggc actcggcagt tctcaaggca tgtcacgcat     2460

gaggaaggcg ggagaggtgt ttttagcttc cttgtatact gaagcttgca aaggctacag     2520

tttacccaac taaacttgac tcctgcattc taatcatgtg ttctttctcc tccatccctg     2580

gacttaggat aactagttgc tggtgatgac ttcgtgtcaa gaacagcagt gaacctgggt     2640

tgcttcccaa attgtggacg aggccttctg ggatgggcag aagtggagaa tggtgattaa     2700

cacacctgtg atccctccct cgctcactcc tctcagtttc cctccaccca acacacttgg     2760

tgtggactcc cctgcacccc gccctagaaa caggacctgg tcctctcact gtcagctgtg     2820

gcagaaggtt gtggcagcgg gttgccttct gtctcggggg tcttgaggct gtcggtccgg     2880

acgatgcagg tgaggcagtg tcagttctgc atcaggaacc cctcgcgctg taatcctttg     2940

atatttttca agccatgaga aaaatgaagt ggacttacca gggtccctcc agtgacctag     3000

tggatgttct tacaggactg ccgtgtgcca ctggctgtgg cttccctggt cctgtgcttg     3060

gccaccggga gctggcatct ccaaaataga gcctccttag cctgtgcagg tgggctgtct     3120

tccaaagtca ccacaccagt gacttgtgct gtgcggagcc ttcctcacca ggaccactgg     3180

ctgctcctgt ggctagaagt cacaattata ggcttcattg caagagccag catttgagtt     3240

tcttctgggc acctgccact gtgcatgtgt gacctcaact gctttgtgca ccctgactgg     3300

ggggtaggtg ctagcgttcc aacattacag atgagaaaac cgaggcacac agaagaggta     3360

acctgcccaa ggtcacaggt gttaggtggc agagccaaga tgttattgtc agtctgactt     3420

caggtgcata aaacctgagg ctgagcctcc ccatgagagg aaaaatgtgt ttgtggtgtg     3480

acctcagttg ccagggaact tgtgcaggaa gccgggagag atggcacaga cccacctgtg     3540

ctcacagtac atgttaagaa ttcccaagtc tcaggcaaac catctccaag ggtgttcaca     3600

gaagacacac cttaaaggca aacgggttca tgatgtaatc ttctattgac tagctgtgaa     3660

cctcattttt cttatctgtg aagtgggaac agtaataatc caagtctttt tatggagtta     3720

tcaagatcaa aaaaggaatg gatatacaaa gtgttttgtg aaataaaagc tccctaaaat     3780

ggtaaaaaaa aaaaaaaaaa a                                               3801


<210>  2132
<211>  3793
<212>  DNA
<213>  homo sapiens

<400>  2132
cccgggggcg ccgcctcccc ccgcaccttc tgcacggctg gcctgccact cctcctgcta       60

tgatgcctgg gcagatcccg gacccttcgg tgaccacagg ctccctgcca gggcttggcc      120

ccctgaccgg gctccccagc tcggccctga ctgtggagga gctgaaatac gctgacatcc      180

gcaacctcgg ggccatgatt gcacccttgc acttcctgga ggtgaaactg ggcaagaggc      240

cccagcccgt gaaaagtgag ctagatgagg aagaggagcg aaggaaaagg cgccgggaga      300

agaacaaagt cgcagcagcc cgatgccgga acaagaagaa ggagcgcacg gagtttctgc      360

agcgggaatc cgagcggctg gaactcatga acgcagagct gaagacccag attgaggagc      420

tgaagcagga gcggcagcag ctcatcctga tgctgaaccg acaccgcccc acctgcatcg      480

tccggaccga cagtgtcaag acccccgagt cagaaggcaa cccactgctc gagcagctcg      540

agaagaagtg accatgggct gggaggaggt ggaggaggag gaagaggaga aggaaaagtg      600

acgaagagag aggaggaggg gggccccaga tggcccttcc tttggtgcat gaaaaactgt      660

acaatgaggt tcagcacagc cagcatcagc cgagcttttt tgtgaaactc agatcagcca      720

cccaggagga agagcgggct gaggaaaccc agagggacca agcgctgaga ccaaagttga      780

ccctcgggta gggttgtcct gcctggggcc ccacttgaag gaggcaggac agaggcaccg      840

aggccaggga gacgcccaac gaggcagccc tgggctcttc tctggcctct tcaccagggc      900

acccatccaa ggaacctccg aacagccagg aaaagccatg agttgcaacc aaaacgcggc      960

tgaggatgga actcagaatg aaactgcaac ccacctgccc ccagccctgc ccctcgccct     1020

gatgcgaagc tggagagggg cgtgctgcgg ggccctgatg cccccaccca cctcggtcca     1080

gcgcggccct gcccaggagg cggcagccgg gcgcaccctc gccagccctg ctggagtttg     1140

ctgtgggcac tgaggcgcgg gcgcccttcc aaagcacata ctcaccgaat gtttacagac     1200

tggctgtcct ggcagggctt tcaactgcac atgtttttta tactttcctt tttttttttt     1260

tttttaatat tttttacaaa aaaaaagatt ttatacaagc aatatatata tggatttcta     1320

taatcactcg atgtgataca gtataaatat gctatggttt gtttgttatg aacagatagc     1380

caccagttac ggccgttgtg tgtaactcct aagtactgta gtctctgggt gtcgggggtg     1440

gccagggcgg gggcggggtg catttccatc cttgtaaacc cttcatagta ctcagtcctg     1500

tatcgctcag taaacattgc tcttacttac atagccgcct tgcgtggtgt ctgcctgggg     1560

aatgggtgca aggccctctc agggtcggag actgtttgga gcctctgcta taggcctgtt     1620

cattttcaca acagctctcc tatttcacag atgaggaagc taaggctcag agacattaag     1680

ccacctgcag ttactatttt gagagcagtc agagtgttcg ctcactctgc agatgttttc     1740

tgagggcctg ttgtgtgtgc caggccctga gaattcactg gaggatgaaa cagacctaag     1800

tcttgccctt gtggggcctc cagtaaggag tgaatcctgt gcttgctcca taagttgtct     1860

catttcgtct tcatggcagc cttgccaggg aacagcactt gtccccaatt cacagatggc     1920

gaattagagg tccagggaat taaactcgca gacaccattt gttgaagact tattttgtga     1980

caagcagaca tagtctcttc ccttctcaca agagcacaaa ctaggcacga ttcttctcat     2040

tttacagatg gtttaactga ggctcagaga aggtaagcga cttatccaag gtaacccagc     2100

tagcaaggga tagagctggt gtttgaactc tccctccaga ggcctgtgac tctcctcctg     2160

tcaccaaccc actatgattg tcctcatggt tgaataggaa gcttatgagg ccacagttat     2220

agatttagtt tctgggaagg ctggatagag ttccaggttg tcccatgatc acagagtgaa     2280

ccaactaccc tggtcaatgt gtgtctgacc cagggaaggg tgtggatggc ttctctgccc     2340

cctcacctcg acagctgaat ccctgccacc cagggccgga gcagctcagt ggcattcact     2400

cagtgcctgc tgtgtacctg gcactcggca gttctcaagg catgtcacgc atgaggaagg     2460

cgggagaggt gtttttagct tccttgtata ctgaagcttg caaaggctac agtttaccca     2520

actaaacttg actcctgcat tctaatcatg tgttctttct cctccatccc tggacttagg     2580

ataactagtt gctggtgatg acttcgtgtc aagaacagca gtgaacctgg gttgcttccc     2640

aaattgtgga cgaggccttc tgggatgggc agaagtggag aatggtgatt aacacacctg     2700

tgatccctcc ctcgctcact cctctcagtt tccctccacc caacacactt ggtgtggact     2760

cccctgcacc ccgccctaga aacaggacct ggtcctctca ctgtcagctg tggcagaagg     2820

ttgtggcagc gggttgcctt ctgtctcggg ggtcttgagg ctgtcggtcc ggacgatgca     2880

ggtgaggcag tgtcagttct gcatcaggaa cccctcgcgc tgtaatcctt tgatattttt     2940

caagccatga gaaaaatgaa gtggacttac cagggtccct ccagtgacct agtggatgtt     3000

cttacaggac tgccgtgtgc cactggctgt ggcttccctg gtcctgtgct tggccaccgg     3060

gagctggcat ctccaaaata gagcctcctt agcctgtgca ggtgggctgt cttccaaagt     3120

caccacacca gtgacttgtg ctgtgcggag ccttcctcac caggaccact ggctgctcct     3180

gtggctagaa gtcacaatta taggcttcat tgcaagagcc agcatttgag tttcttctgg     3240

gcacctgcca ctgtgcatgt gtgacctcaa ctgctttgtg caccctgact ggggggtagg     3300

tgctagcgtt ccaacattac agatgagaaa accgaggcac acagaagagg taacctgccc     3360

aaggtcacag gtgttaggtg gcagagccaa gatgttattg tcagtctgac ttcaggtgca     3420

taaaacctga ggctgagcct ccccatgaga ggaaaaatgt gtttgtggtg tgacctcagt     3480

tgccagggaa cttgtgcagg aagccgggag agatggcaca gacccacctg tgctcacagt     3540

acatgttaag aattcccaag tctcaggcaa accatctcca agggtgttca cagaagacac     3600

accttaaagg caaacgggtt catgatgtaa tcttctattg actagctgtg aacctcattt     3660

ttcttatctg tgaagtggga acagtaataa tccaagtctt tttatggagt tatcaagatc     3720

aaaaaaggaa tggatataca aagtgttttg tgaaataaaa gctccctaaa atggtaaaaa     3780

aaaaaaaaaa aaa                                                        3793


<210>  2133
<211>  3960
<212>  DNA
<213>  homo sapiens

<400>  2133
ctgaagaggg ccttttgctg ctcgccttca ctctcagtct tggggccttc cccatcatct       60

tgcttctcgc cttctggatc tcctcgactt ttggaagccg cgtgacctac gtcattcaga      120

ttccaagaga gaggtcatcc tgggtgattc cttagctcca agaagaggct tggtggttga      180

ttctccaaga ttcatggtag caggctggcc tgccactcct cctgctatga tgcctgggca      240

gatcccggac ccttcggtga ccacaggctc cctgccaggg cttggccccc tgaccgggct      300

ccccagctcg gccctgactg tggaggagct gaaatacgct gacatccgca acctcggggc      360

catgattgca cccttgcact tcctggaggt gaaactgggc aagaggcccc agcccgtgaa      420

aagtgagcta gatgaggaag aggagcgaag gaaaaggcgc cgggagaaga acaaagtcgc      480

agcagcccga tgccggaaca agaagaagga gcgcacggag tttctgcagc gggaatccga      540

gcggctggaa ctcatgaacg cagagctgaa gacccagatt gaggagctga agcaggagcg      600

gcagcagctc atcctgatgc tgaaccgaca ccgccccacc tgcatcgtcc ggaccgacag      660

tgtcaagacc cccgagtcag aaggcaaccc actgctcgag cagctcgaga agaagtgacc      720

atgggctggg aggaggtgga ggaggaggaa gaggagaagg aaaagtgacg aagagagagg      780

aggagggggg ccccagatgg cccttccttt ggtgcatgaa aaactgtaca atgaggttca      840

gcacagccag catcagccga gcttttttgt gaaactcaga tcagccaccc aggaggaaga      900

gcgggctgag gaaacccaga gggaccaagc gctgagacca aagttgaccc tcgggtaggg      960

ttgtcctgcc tggggcccca cttgaaggag gcaggacaga ggcaccgagg ccagggagac     1020

gcccaacgag gcagccctgg gctcttctct ggcctcttca ccagggcacc catccaagga     1080

acctccgaac agccaggaaa agccatgagt tgcaaccaaa acgcggctga ggatggaact     1140

cagaatgaaa ctgcaaccca cctgccccca gccctgcccc tcgccctgat gcgaagctgg     1200

agaggggcgt gctgcggggc cctgatgccc ccacccacct cggtccagcg cggccctgcc     1260

caggaggcgg cagccgggcg caccctcgcc agccctgctg gagtttgctg tgggcactga     1320

ggcgcgggcg cccttccaaa gcacatactc accgaatgtt tacagactgg ctgtcctggc     1380

agggctttca actgcacatg ttttttatac tttccttttt tttttttttt ttaatatttt     1440

ttacaaaaaa aaagatttta tacaagcaat atatatatgg atttctataa tcactcgatg     1500

tgatacagta taaatatgct atggtttgtt tgttatgaac agatagccac cagttacggc     1560

cgttgtgtgt aactcctaag tactgtagtc tctgggtgtc gggggtggcc agggcggggg     1620

cggggtgcat ttccatcctt gtaaaccctt catagtactc agtcctgtat cgctcagtaa     1680

acattgctct tacttacata gccgccttgc gtggtgtctg cctggggaat gggtgcaagg     1740

ccctctcagg gtcggagact gtttggagcc tctgctatag gcctgttcat tttcacaaca     1800

gctctcctat ttcacagatg aggaagctaa ggctcagaga cattaagcca cctgcagtta     1860

ctattttgag agcagtcaga gtgttcgctc actctgcaga tgttttctga gggcctgttg     1920

tgtgtgccag gccctgagaa ttcactggag gatgaaacag acctaagtct tgcccttgtg     1980

gggcctccag taaggagtga atcctgtgct tgctccataa gttgtctcat ttcgtcttca     2040

tggcagcctt gccagggaac agcacttgtc cccaattcac agatggcgaa ttagaggtcc     2100

agggaattaa actcgcagac accatttgtt gaagacttat tttgtgacaa gcagacatag     2160

tctcttccct tctcacaaga gcacaaacta ggcacgattc ttctcatttt acagatggtt     2220

taactgaggc tcagagaagg taagcgactt atccaaggta acccagctag caagggatag     2280

agctggtgtt tgaactctcc ctccagaggc ctgtgactct cctcctgtca ccaacccact     2340

atgattgtcc tcatggttga ataggaagct tatgaggcca cagttataga tttagtttct     2400

gggaaggctg gatagagttc caggttgtcc catgatcaca gagtgaacca actaccctgg     2460

tcaatgtgtg tctgacccag ggaagggtgt ggatggcttc tctgccccct cacctcgaca     2520

gctgaatccc tgccacccag ggccggagca gctcagtggc attcactcag tgcctgctgt     2580

gtacctggca ctcggcagtt ctcaaggcat gtcacgcatg aggaaggcgg gagaggtgtt     2640

tttagcttcc ttgtatactg aagcttgcaa aggctacagt ttacccaact aaacttgact     2700

cctgcattct aatcatgtgt tctttctcct ccatccctgg acttaggata actagttgct     2760

ggtgatgact tcgtgtcaag aacagcagtg aacctgggtt gcttcccaaa ttgtggacga     2820

ggccttctgg gatgggcaga agtggagaat ggtgattaac acacctgtga tccctccctc     2880

gctcactcct ctcagtttcc ctccacccaa cacacttggt gtggactccc ctgcaccccg     2940

ccctagaaac aggacctggt cctctcactg tcagctgtgg cagaaggttg tggcagcggg     3000

ttgccttctg tctcgggggt cttgaggctg tcggtccgga cgatgcaggt gaggcagtgt     3060

cagttctgca tcaggaaccc ctcgcgctgt aatcctttga tatttttcaa gccatgagaa     3120

aaatgaagtg gacttaccag ggtccctcca gtgacctagt ggatgttctt acaggactgc     3180

cgtgtgccac tggctgtggc ttccctggtc ctgtgcttgg ccaccgggag ctggcatctc     3240

caaaatagag cctccttagc ctgtgcaggt gggctgtctt ccaaagtcac cacaccagtg     3300

acttgtgctg tgcggagcct tcctcaccag gaccactggc tgctcctgtg gctagaagtc     3360

acaattatag gcttcattgc aagagccagc atttgagttt cttctgggca cctgccactg     3420

tgcatgtgtg acctcaactg ctttgtgcac cctgactggg gggtaggtgc tagcgttcca     3480

acattacaga tgagaaaacc gaggcacaca gaagaggtaa cctgcccaag gtcacaggtg     3540

ttaggtggca gagccaagat gttattgtca gtctgacttc aggtgcataa aacctgaggc     3600

tgagcctccc catgagagga aaaatgtgtt tgtggtgtga cctcagttgc cagggaactt     3660

gtgcaggaag ccgggagaga tggcacagac ccacctgtgc tcacagtaca tgttaagaat     3720

tcccaagtct caggcaaacc atctccaagg gtgttcacag aagacacacc ttaaaggcaa     3780

acgggttcat gatgtaatct tctattgact agctgtgaac ctcatttttc ttatctgtga     3840

agtgggaaca gtaataatcc aagtcttttt atggagttat caagatcaaa aaaggaatgg     3900

atatacaaag tgttttgtga aataaaagct ccctaaaatg gtaaaaaaaa aaaaaaaaaa     3960


<210>  2134
<211>  4007
<212>  DNA
<213>  homo sapiens

<400>  2134
gccccagccc agccccgcgg ggaggctccc gcagcccagg gacctcgagc tttccccgcg       60

ccgggcgctg cagccgggcc cctcccgcga ggcgcccggc agcctgaggc ttccttttgg      120

ttcccgcccc gggacgggag gctccgtccg ctccctggac agccggggtg ctccctcctt      180

ctccctcccg cgctctcctc ccccgtccgt ttgcagggag gtgctctcct cgggcggcgg      240

ggaaggcggg gctggcctgc cactcctcct gctatgatgc ctgggcagat cccggaccct      300

tcggtgacca caggctccct gccagggctt ggccccctga ccgggctccc cagctcggcc      360

ctgactgtgg aggagctgaa atacgctgac atccgcaacc tcggggccat gattgcaccc      420

ttgcacttcc tggaggtgaa actgggcaag aggccccagc ccgtgaaaag tgagctagat      480

gaggaagagg agcgaaggaa aaggcgccgg gagaagaaca aagtcgcagc agcccgatgc      540

cggaacaaga agaaggagcg cacggagttt ctgcagcggg aatccgagcg gctggaactc      600

atgaacgcag agctgaagac ccagattgag gagctgaagc aggagcggca gcagctcatc      660

ctgatgctga accgacaccg ccccacctgc atcgtccgga ccgacagtgt caagaccccc      720

gagtcagaag gcaacccact gctcgagcag ctcgagaaga agtgaccatg ggctgggagg      780

aggtggagga ggaggaagag gagaaggaaa agtgacgaag agagaggagg aggggggccc      840

cagatggccc ttcctttggt gcatgaaaaa ctgtacaatg aggttcagca cagccagcat      900

cagccgagct tttttgtgaa actcagatca gccacccagg aggaagagcg ggctgaggaa      960

acccagaggg accaagcgct gagaccaaag ttgaccctcg ggtagggttg tcctgcctgg     1020

ggccccactt gaaggaggca ggacagaggc accgaggcca gggagacgcc caacgaggca     1080

gccctgggct cttctctggc ctcttcacca gggcacccat ccaaggaacc tccgaacagc     1140

caggaaaagc catgagttgc aaccaaaacg cggctgagga tggaactcag aatgaaactg     1200

caacccacct gcccccagcc ctgcccctcg ccctgatgcg aagctggaga ggggcgtgct     1260

gcggggccct gatgccccca cccacctcgg tccagcgcgg ccctgcccag gaggcggcag     1320

ccgggcgcac cctcgccagc cctgctggag tttgctgtgg gcactgaggc gcgggcgccc     1380

ttccaaagca catactcacc gaatgtttac agactggctg tcctggcagg gctttcaact     1440

gcacatgttt tttatacttt cctttttttt ttttttttta atatttttta caaaaaaaaa     1500

gattttatac aagcaatata tatatggatt tctataatca ctcgatgtga tacagtataa     1560

atatgctatg gtttgtttgt tatgaacaga tagccaccag ttacggccgt tgtgtgtaac     1620

tcctaagtac tgtagtctct gggtgtcggg ggtggccagg gcgggggcgg ggtgcatttc     1680

catccttgta aacccttcat agtactcagt cctgtatcgc tcagtaaaca ttgctcttac     1740

ttacatagcc gccttgcgtg gtgtctgcct ggggaatggg tgcaaggccc tctcagggtc     1800

ggagactgtt tggagcctct gctataggcc tgttcatttt cacaacagct ctcctatttc     1860

acagatgagg aagctaaggc tcagagacat taagccacct gcagttacta ttttgagagc     1920

agtcagagtg ttcgctcact ctgcagatgt tttctgaggg cctgttgtgt gtgccaggcc     1980

ctgagaattc actggaggat gaaacagacc taagtcttgc ccttgtgggg cctccagtaa     2040

ggagtgaatc ctgtgcttgc tccataagtt gtctcatttc gtcttcatgg cagccttgcc     2100

agggaacagc acttgtcccc aattcacaga tggcgaatta gaggtccagg gaattaaact     2160

cgcagacacc atttgttgaa gacttatttt gtgacaagca gacatagtct cttcccttct     2220

cacaagagca caaactaggc acgattcttc tcattttaca gatggtttaa ctgaggctca     2280

gagaaggtaa gcgacttatc caaggtaacc cagctagcaa gggatagagc tggtgtttga     2340

actctccctc cagaggcctg tgactctcct cctgtcacca acccactatg attgtcctca     2400

tggttgaata ggaagcttat gaggccacag ttatagattt agtttctggg aaggctggat     2460

agagttccag gttgtcccat gatcacagag tgaaccaact accctggtca atgtgtgtct     2520

gacccaggga agggtgtgga tggcttctct gccccctcac ctcgacagct gaatccctgc     2580

cacccagggc cggagcagct cagtggcatt cactcagtgc ctgctgtgta cctggcactc     2640

ggcagttctc aaggcatgtc acgcatgagg aaggcgggag aggtgttttt agcttccttg     2700

tatactgaag cttgcaaagg ctacagttta cccaactaaa cttgactcct gcattctaat     2760

catgtgttct ttctcctcca tccctggact taggataact agttgctggt gatgacttcg     2820

tgtcaagaac agcagtgaac ctgggttgct tcccaaattg tggacgaggc cttctgggat     2880

gggcagaagt ggagaatggt gattaacaca cctgtgatcc ctccctcgct cactcctctc     2940

agtttccctc cacccaacac acttggtgtg gactcccctg caccccgccc tagaaacagg     3000

acctggtcct ctcactgtca gctgtggcag aaggttgtgg cagcgggttg ccttctgtct     3060

cgggggtctt gaggctgtcg gtccggacga tgcaggtgag gcagtgtcag ttctgcatca     3120

ggaacccctc gcgctgtaat cctttgatat ttttcaagcc atgagaaaaa tgaagtggac     3180

ttaccagggt ccctccagtg acctagtgga tgttcttaca ggactgccgt gtgccactgg     3240

ctgtggcttc cctggtcctg tgcttggcca ccgggagctg gcatctccaa aatagagcct     3300

ccttagcctg tgcaggtggg ctgtcttcca aagtcaccac accagtgact tgtgctgtgc     3360

ggagccttcc tcaccaggac cactggctgc tcctgtggct agaagtcaca attataggct     3420

tcattgcaag agccagcatt tgagtttctt ctgggcacct gccactgtgc atgtgtgacc     3480

tcaactgctt tgtgcaccct gactgggggg taggtgctag cgttccaaca ttacagatga     3540

gaaaaccgag gcacacagaa gaggtaacct gcccaaggtc acaggtgtta ggtggcagag     3600

ccaagatgtt attgtcagtc tgacttcagg tgcataaaac ctgaggctga gcctccccat     3660

gagaggaaaa atgtgtttgt ggtgtgacct cagttgccag ggaacttgtg caggaagccg     3720

ggagagatgg cacagaccca cctgtgctca cagtacatgt taagaattcc caagtctcag     3780

gcaaaccatc tccaagggtg ttcacagaag acacacctta aaggcaaacg ggttcatgat     3840

gtaatcttct attgactagc tgtgaacctc atttttctta tctgtgaagt gggaacagta     3900

ataatccaag tctttttatg gagttatcaa gatcaaaaaa ggaatggata tacaaagtgt     3960

tttgtgaaat aaaagctccc taaaatggta aaaaaaaaaa aaaaaaa                   4007


<210>  2135
<211>  4233
<212>  DNA
<213>  homo sapiens

<400>  2135
aaagtgagtg agtgagacgg gcagatggag gagggattgt aatggcggca gccggcagct       60

ccctgctctg acccacggca ggcacacagc aacgacccct tccccgcccc tctcccggcc      120

ggcctccgcc ccgcagccag cgcggggcca ccctctccgg cccttccccc agctgtcggc      180

gtctcgccct gcgccccggc cggggcccca cacacaatgg acgagcttgc cggaggcggt      240

ggtggcggcc cggggatggc ggcccctccc cggcagcagc agggacctgg ggggaacctg      300

ggcctttcgc ccggggggaa cggagcggcg ggcggcgggg gtcctccggc ctccgaggga      360

gcgggtcccg cggcaggccc cgagctgtcc cggccgcagc agtacactat cccggggata      420

ctgcactaca tccagcacga gtgggctcgg ttcgagatgg agcgggcgca ctgggaggtg      480

gaacgggccg aactgcaggc ccggattgca tttctacaag gcgaaagaaa aggtcaagag      540

aacctgaaga aggacttagt aagaagaata aagatgttag agtatgcatt aaaacaagaa      600

agggcaaaat atcacaaatt aaaatatggc acggaactga accaaggtga cttgaaaatg      660

ccaacctttg agtcagaaga aaccaaagac acagaggctc ccacagcacc tcagaatagc      720

cagttaacgt ggaagcaagg cagacagctt ttaagacagt atcttcagga agtaggttat      780

acagatacaa tattagatgt acggtctcag cgggtaaggt cattacttgg actatctaat      840

tcagaaccaa atggatcagt agaaacaaag aatttagaac agatcctgaa tggaggtgaa      900

tctcctaagc aaaagggaca agaaataaaa aggtcctctg gtgatgttct tgagacgttc      960

aatttcttag aaaatgccga tgacagtgat gaagatgagg aaaatgacat gatcgaaggc     1020

atcccagaag gaaaagacaa acatcggatg aataaacata aaataggtaa tgaaggttta     1080

gctgctgacc taactgacga tcctgatact gaggaagcac tgaaagaatt tgatttttta     1140

gtgactgctg aagatggtga aggagctgga gaagcacgga gttcggggga tggcacagaa     1200

tgggataaag atgacctctc cccaactgct gaggtttggg atgtagacca gggactaata     1260

agtaaactga aggaacagta caagaaggaa cgaaagggga agaaaggggt gaagagggcc     1320

aacaggacaa aactctacga catgatagct gatctgggag atgatgagct gccccacatc     1380

ccttcaggaa tcattaatca gtctaggtca gcctctacta gaatgactga tcatgaaggt     1440

gcaagagcag aggaagctga accaataacg tttccatctg gaggaggcaa gtcatttatt     1500

atgggttctg atgatgtttt gttaagtgta ctgggccttg gagaccttgc agacttgacg     1560

gtaacaaatg atgcagacta tagttatgat ttgcctgcta ataaagatgc ctttcgaaag     1620

acatggaatc ccaagtatac actacgtagc cattttgatg gagtacgggc attagctttt     1680

catcctgtag aacctgtgct ggttactgct tctgaggacc ataccctgaa actttggaac     1740

ctgcaaaaaa cagttcctgc caaaaagagt gcctctttag atgtagagcc tatctacaca     1800

tttagggccc acatcggccc tgttctgtca ttagctatta gttctaatgg agaacagtgt     1860

tttagtggtg gtattgatgc aaccatccag tggtggaata tgccgagtcc cagtgtagat     1920

ccatatgata catatgagcc aaatgttcta gctggcactt tagttggtca tacagatgca     1980

gtttggggtc ttgcttatag tggcataaaa aatcaattac tgtcttgttc agcagatggc     2040

actgttaggt tatggaatcc acaagaaaaa ttgccatgta tttgcactta caatggagat     2100

aaaaagcatg gaatacctac atcagttgac tttataggct gtgatccagc tcatatggta     2160

acctctttca acactggtag tgcagtaatt tatgatttag aaacatcaca gtcattggtg     2220

atactttcat cacaggtaga ttctggttta caatctaata atcatatcaa cagagtagta     2280

agtcatccca cacttcctgt tacaataact gctcatgaag atagacacat caaatttttt     2340

gacaataaaa cgggtaaaat gatccattct atggtagctc acttggatgc tgttacaagt     2400

ctagcagtag atcctaatgg aatctatttg atgtctggaa gccatgactg ttccatcaga     2460

ttatggaatt tagacagcaa gacatgtgtg caagaaataa cagctcacag aaagaaattg     2520

gatgaatcaa tttatgatgt tgctttccac tcgtcaaaag catatatagc tagtgcagga     2580

gctgatgctc ttgccaaagt atttgtatga atcaacaaaa acttgcatcg taacaagatt     2640

tgcttggaca gaaagagggt ctgcatcact gccatcagaa aggttactga tatgacacta     2700

catgtgatct gcctggtgaa ggctatctgg ggcaggcaca aattggtgga aatcacatct     2760

taatgtcaag ctcattaagt taactgtaat tactgtattt tgtgggacaa agaaaaaagg     2820

actccagtat ttgtggcctg tactggatgt gaactgagcg tatatctgtt tttaggtgtc     2880

tttaagccaa tgtggagtct gatctttcaa aaaagttttt ttttttctct tcttcttctt     2940

cttttttttt tttttttttt tttttttgga ctctgtgtgc tgccttaggg gttaggaatg     3000

tggtgctctt gttgggggaa gtgagctcca agagtagctt tttttcatct cttagtgatc     3060

ttctgtttat cggttgaatg ccacagattc ccttttaaac ttattttgct ttaaaaaaaa     3120

aaaaaaagaa aaagaaaatt taacttaaaa tattttagca ttagttgcac aaaatgtttg     3180

gataaaattc tagtttttat aagtcttttt atatatttag cctgtcacaa cagtgctcaa     3240

gattgtattg aagtttttct gcattataca accctaaaac acagagatct cactgacccg     3300

ttgccctgta accactttct ttccttcttt tgcctaatac agctcagcta agtccttcca     3360

taaagatgct aaataacttt catcatcaca taaatgtctt cataaaccaa ggactattaa     3420

gtgtattaaa atgaaacagt ggggtttagt actccaaatg aactcttaaa gaaaaaaact     3480

aatcttggca tcctatcact atgtgatatt ttgtacatct tactgtattt acaagtttat     3540

ttatcaagga ttatccatct tgctaatggc ctattattta tttcactttt tgttggtctt     3600

tatatccttt tattaatgtg ctaaaggaac ctgtatatct attttggaac tctttgaata     3660

gtctaaaata gactaaaaat ggagtatttt atagtttaaa ttacaaacca aggtggttcc     3720

ccctaagata tatatcttgg tttaccatga ttccaaacaa aactaacttg tttaaaaata     3780

tttggagtaa agttttattt gcattacaaa taggatacaa aaatagttga atcaggatac     3840

agaaatctgc tgtgttttga ctagttatcc ctgttttatt tttttagatg tgcttaattt     3900

tatggtgtaa ctaaagattt tgtttgtgta atgcatgatt aagacaataa agtatttttt     3960

ctagtcttcc gagaaacttt tctgatcagt ttgcgagttt tgatgagttt tgtaaggttt     4020

ttgttttaca aactatgaat cagcaaattt ttaagattgt accacatagc aaacatacag     4080

ctgttgaaaa ataatgtata taaaatgcat ataataaata ttaaattgtg tacctgtatg     4140

ttactgttgg ctacatcatt ttgtgttgaa taataaagtg caatacttta ttctccataa     4200

ttaaactagg aaatggagat ttaaaaaaaa aaa                                  4233


<210>  2136
<211>  5935
<212>  DNA
<213>  homo sapiens

<400>  2136
cttttcccat cgtgtagtca agagtctgtg ccagacttga aggctttact ttgttagcca       60

tgtgtttatg aacccccagc gctttcccta gatcttttgg ctgataatct caaacatgga      120

ggatgcttct gaatcttcac gaggggttgc tccattaatt aataatgtag ttctcccagg      180

ctctccgctg tctcttcctg tatcagtgac aggctgtaaa agtcatcgag tagccaataa      240

aaaggtagaa gcgaggagtg aaaagctcct cccaacagct cttcctcctt cagagccgaa      300

agtagatcag aaacttccca ggagctccga gaggcgggga agtggcggtg ggacgcaatt      360

ccccgcgcgg agtcgggcag tggcagcggg agaagcggca gccaggggcg cggcggggcc      420

ggagagaggc ggtcccctgg gaggacgggg tctcccctcg ttgcctttgt agtggagaag      480

gtggacaagt ggcagtcggc gtgatcgcag ggaagcgggg ccggcgcggg cggccgaggg      540

tccaggcgag cccgcgggcg gacgggagat gccgctgcta caccgaaagc cgtttgtgag      600

acagaagccg cccgcggacc tgcggcccga cgaggaagtt ttctactgta aagtcaccaa      660

cgagatcttc cgccactacg atgacttttt tgaacgaacc attctgtgca acagccttgt      720

gtggagttgt gctgtgacgg gtagacctgg actgacgtat caggaagcac ttgagtcaga      780

aaaaaaagca agacagaatc ttcagagttt tccagaacca ctaattattc cagttttata      840

cttgaccagc cttacccatc gttcgcgctt acatgaaatt tgtgatgata tctttgcata      900

tgtcaaggat cgatattttg tcgaagaaac tgtggaagtc attaggaaca atggtgcaag      960

gttgcagtgt aggattttgg aagtcctccc tccatcacat caaaatggtt ttgctaatgg     1020

acatgttaac agtgtggatg gagaaactat tatcatcagt gatagtgatg attcagaaac     1080

acaaagctgt tcttttcaaa atgggaagaa aaaagatgca attgatccct tactattcaa     1140

gtataaagtg caacccacta aaaaagaatt acatgagtct gctattgtta aagcaacaca     1200

aatcagccgg agaaaacacc tattttctcg tgataaacta aagctttttc tgaagcaaca     1260

ctgtgaacca caagatggag tcattaaaat aaaggcatca tctctttcaa cgtataaaat     1320

agcagaacaa gatttttctt atttcttccc tgatgatcca cccacattta tcttcagtcc     1380

tgctaacaga cgaagaggga gacctcccaa acgaatacat attagtcaag aggacaatgt     1440

tgctaataaa cagactcttg caagttatag gagcaaagct actaaagaaa gagataaact     1500

tttgaaacaa gaagaaatga agtcactggc ttttgaaaag gctaaattaa aaagagaaaa     1560

agcagatgcc ctagaagcga agaaaaaaga aaaagaagat aaagagaaaa agagggaaga     1620

attgaaaaaa attgttgaag aagagagact aaagaaaaaa gaagaaaaag agaggcttaa     1680

agtagaaaga gaaaaggaaa gagagaagtt acgtgaagaa aagcgaaagt atgtggaata     1740

cttaaaacag tggagtaaac ctagagaaga tatggaatgt gatgacctta aggaacttcc     1800

agaaccaaca ccagtgaaaa ctagactacc tcctgaaatc tttggtgatg ctctgatggt     1860

tttggagttc cttaatgcat ttggggaact ttttgatctt caagatgagt ttcctgatgg     1920

agtaacccta gaagtattag aggaagctct tgtaggaaat gacagtgaag gcccactgtg     1980

tgaattgctt tttttcttcc tgactgcaat cttccaggca atagctgaag aagaagagga     2040

agtagccaaa gagcaactaa ctgatgctga caccaaaggc tgcagtttga aaagtttgga     2100

tcttgatagc tgcactcttt cagaaatcct cagactgcac atcttagctt caggtgctga     2160

tgtaacatca gcaaatgcaa agtatagata tcaaaaacga ggaggatttg atgctacaga     2220

tgatgcttgt atggagcttc gtttgagcaa tcccagtcta gtgaagaaac tgtcaagcac     2280

ctcagtgtat gatttgacac caggagaaaa aatgaagata ctccatgctc tctgtggaaa     2340

gctactgacc ctagtttcaa ctagggattt tattgaagat tatgttgata tattacgaca     2400

ggcaaagcag gagttccggg aattaaaagc agaacaacat cgaaaagaga gggaagaagc     2460

agctgccaga attcgtaaaa ggaaggaaga aaaacttaag gagcaagaac aaaaaatgaa     2520

agagaaacaa gaaaaactga aagaagatga gcaaagaaat tcaacggcag atatatctat     2580

tggggaggaa gaaagggaag attttgatac tagcattgag agcaaagaca cagagcaaaa     2640

ggaattagat caagatatgg tcactgaaga tgaagatgac ccaggatcac ataaaagagg     2700

cagaaggggg aaaagaggac aaaatggatt taaagaattt acaaggcaag aacagatcaa     2760

ctgtgtaaca agagagcctc ttactgctga tgaggaagaa gcattaaaac aggaacacca     2820

acgaaaagag aaagagctct tagaaaaaat ccaaagtgcc atagcctgta ccaatatctt     2880

tcccttgggt cgcgaccgca tgtatagacg atactggatt ttcccttcta ttcctggact     2940

ctttattgaa gaggattatt ctggtcttac tgaagacatg ctgttgccta gaccttcatc     3000

atttcagaat aatgtacagt ctcaagatcc tcaggtatcc actaaaactg gagagccttt     3060

gatgtctgaa tctacctcca acattgacca aggtccacgt gaccattctg tgcagctgcc     3120

aaaaccagtg cataagccaa atcggtggtg cttttacagt tcttgtgaac agctagacca     3180

gcttattgaa gctcttaatt ctagaggaca tagagaaagt gccttaaaag aaactttgtt     3240

acaagagaaa agcagaatat gtgcacagct agcccgtttt tctgaagaga aatttcattt     3300

ttcagacaaa cctcagcctg atagcaaacc aacatatagt cggggaagat cttccaatgc     3360

atatgatcca tctcagatgt gtgcagaaaa gcaacttgaa ctaaggctga gagattttct     3420

tttagatatt gaagatagaa tctaccaagg aacattagga gccatcaagg ttacagatcg     3480

acatatctgg agatcagcat tagaaagtgg acggtatgag ctgttaagtg aggaaaacaa     3540

ggaaaatggg ataattaaaa ctgtgaatga agacgtagaa gagatggaaa ttgatgaaca     3600

aacaaaggtc atagtaaaag acagactttt ggggataaaa acagaaactc caagtactgt     3660

atcaacaaat gcaagtacac cacaatcagt gagcagtgtg gttcattatc tggcaatggc     3720

actctttcaa atagagcagg gcattgagcg gcgttttctg aaagctccac ttgatgccag     3780

tgacagtggg cgttcttata aaacagttct ggaccgttgg agagagtctc tcctttcttc     3840

tgctagtcta tcccaagttt ttcttcacct atccaccttg gatcgtagcg tgatatggtc     3900

taaatctata ctgaatgcgc gttgcaagat atgtcgaaag aaaggcgatg ctgaaaacat     3960

ggttctttgt gatggctgtg ataggggtca tcatacctac tgtgttcgac caaagctcaa     4020

gactgtgcct gaaggagact ggttttgtcc agaatgtcga ccaaagcaac gttctagaag     4080

actctcctct agacagagac catccttgga aagtgatgaa gatgtggaag acagtatggg     4140

aggtgaggat gatgaagttg atggcgatga agaagaaggt caaagtgagg aggaagagta     4200

tgaggtagaa caagatgaag atgactctca agaagaggaa gaagtcagcc tacccaaacg     4260

aggaagacca caagttagat tgccagttaa aacaagaggg aaacttagct cttctttctc     4320

aagtcgtggc caacaacaag aacctggaag atacccttca aggagtcagc agagcacacc     4380

caaaacaact gtttcttcta aaactggtag aagcctaaga aagataaact ctgctcctcc     4440

tacagaaaca aaatctttaa gaattgccag tcgttctact cgccacagtc atggcccact     4500

gcaagcagat gtatttgtgg aattgcttag tcctcgtaga aaacgcagag gcaggaaaag     4560

tgctaataat acaccagaaa atagtcccaa cttccctaac ttcagagtca ttgccacaaa     4620

gtcaagtgaa cagtcaagat ctgtaaatat tgcttcaaaa ctttctctcc aagagagtga     4680

atccaaaaga agatgcagaa aaagacaatc tccagagcca tcgcctgtga cactgggtcg     4740

aaggagttct ggccgacagg gaggagttca tgaattgtct gcttttgaac aacttgttgt     4800

agaattggta cgacatgatg acagctggcc ttttttgaaa cttgtttcta aaatccaggt     4860

cccagactac tatgacatca tcaaaaagcc cattgcctta aatataattc gtgaaaaagt     4920

gaataagtgt gaatataaat tagcatctga gtttattgat gacattgagt taatgttttc     4980

gaactgcttt gaatacaacc ctcgtaacac aagtgaagca aaagctggaa ctaggcttca     5040

agcatttttt catattcagg ctcaaaagct tggactccac gtcacaccca gtaatgtgga     5100

ccaagttagc acaccaccgg ctgcgaaaaa gtcacgaatc tgactttgtc cttctaaagg     5160

atatatttga agaaaaacaa attgttcatg aaaatggaac attaaatcat gctgtataaa     5220

gcaataacaa ttgattgacc acatgaaagt gtggcctgca ctatattctc aattttaata     5280

ttaagcactc aggagaatgt aggaaagata tcctttgcta cagttttgtt cagtatctaa     5340

taagtttgat agatgtattg gatacagtac tggtttacag aggtttttgt acatttttga     5400

gatcattcat gtgtccagag atcttggaaa atattttttc acccacgatt tattttgtta     5460

ttgatgattt ttttttaaag tggtggtatt aagggagagt tatctacatg gatgagtctt     5520

ccgctatagc acagtttaga aaaggtgttt atgtcttaat taattgtttg agtacattct     5580

ttcaacacta cacatgaatg aatccaatct tataaccttg aagtgctgta ccagtgctgg     5640

ctgcaggtat taagtccaag tttattaact agatatttat ttagtattga gagtaatttg     5700

tgaatttgtt ttgtatttat aaaatttata cctgaaaaat gttccttaat gttttaaacc     5760

ttttactgtg tttttattcc tctaacttcc ttaatgatca atcaaaaaaa gtaacaccct     5820

ccctttttcc tgacagttct ttcagcttta cagaactgta ttataagttt ctatgtataa     5880

ctttttaact gtacaaataa aataacattt tttcaaataa aaaaaaaaaa aaaaa          5935


<210>  2137
<211>  3178
<212>  DNA
<213>  homo sapiens

<400>  2137
agccccgccc ccgcttgcgc gaggcctagg gctgcaggcg cggagccgcg agccccagcc       60

aatgagcgcc ggcgggccgg ttgcccaggc gaccagtgcg cggctccgcc ccccgcggcg      120

aggctcccgc gcgcggctga gtgcggactg gagtgggaac ccgggtcccc gcgcttagag      180

aacacgcgat gaccacgtgg agcctccggc ggaggccggc ccgcacgctg ggactcctgc      240

tgctggtcgt cttgggcttc ctggtgctcc gcaggctgga ctggagcacc ctggtccctc      300

tgcggctccg ccatcgacag ctggggctgc aggccaaggg ctggaacttc atgctggagg      360

attccacctt ctggatcttc gggggctcca tccactattt ccgtgtgccc agggagtact      420

ggagggaccg cctgctgaag atgaaggcct gtggcttgaa caccctcacc acctatgttc      480

cgtggaacct gcatgagcca gaaagaggca aatttgactt ctctgggaac ctggacctgg      540

aggccttcgt cctgatggcc gcagagatcg ggctgtgggt gattctgcgt ccaggcccct      600

acatctgcag tgagatggac ctcgggggct tgcccagctg gctactccaa gaccctggca      660

tgaggctgag gacaacttac aagggcttca ccgaagcagt ggacctttat tttgaccacc      720

tgatgtccag ggtggtgcca ctccagtaca agcgtggggg acctatcatt gccgtgcagg      780

tggagaatga atatggttcc tataataaag accccgcata catgccctac gtcaagaagg      840

cactggagga ccgtggcatt gtggaactgc tcctgacttc agacaacaag gatgggctga      900

gcaaggggat tgtccaggga gtcttggcca ccatcaactt gcagtcaaca cacgagctgc      960

agctactgac cacctttctc ttcaacgtcc aggggactca gcccaagatg gtgatggagt     1020

actggacggg gtggtttgac tcgtggggag gccctcacaa tatcttggat tcttctgagg     1080

ttttgaaaac cgtgtctgcc attgtggacg ccggctcctc catcaacctc tacatgttcc     1140

acggaggcac caactttggc ttcatgaatg gagccatgca cttccatgac tacaagtcag     1200

atgtcaccag ctatgactat gatgctgtgc tgacagaagc cggcgattac acggccaagt     1260

acatgaagct tcgagacttc ttcggctcca tctcaggcat ccctctccct cccccacctg     1320

accttcttcc caagatgccg tatgagccct taacgccagt cttgtacctg tctctgtggg     1380

acgccctcaa gtacctgggg gagccaatca agtctgaaaa gcccatcaac atggagaacc     1440

tgccagtcaa tgggggaaat ggacagtcct tcgggtacat tctctatgag accagcatca     1500

cctcgtctgg catcctcagt ggccacgtgc atgatcgggg gcaggtgttt gtgaacacag     1560

tatccatagg attcttggac tacaagacaa cgaagattgc tgtccccctg atccagggtt     1620

acaccgtgct gaggatcttg gtggagaatc gtgggcgagt caactatggg gagaatattg     1680

atgaccagcg caaaggctta attggaaatc tctatctgaa tgattcaccc ctgaaaaact     1740

tcagaatcta tagcctggat atgaagaaga gcttctttca gaggttcggc ctggacaaat     1800

ggagttccct cccagaaaca cccacattac ctgctttctt cttgggtagc ttgtccatca     1860

gctccacccc ttgtgacacc tttctgaagc tggagggctg ggagaagggg gttgtattca     1920

tcaatggcca gaaccttgga cgttactgga acattggacc ccagaagacg ctttacctcc     1980

caggtccctg gttgagcagc ggaatcaacc aggtcatcgt ttttgaggag acgatggcgg     2040

gccctgcatt acagttcacg gaaacccccc acctgggcag gaaccagtac attaagtgag     2100

cggtggcacc ccctcctgct ggtgccagtg ggagactgcc gcctcctctt gacctgaagc     2160

ctggtggctg ctgccccacc cctcactgca aaagcatctc cttaagtagc aacctcaggg     2220

actgggggct acagtctgcc cctgtctcag ctcaaaaccc taagcctgca gggaaaggtg     2280

ggatggctct gggcctggct ttgttgatga tggctttcct acagccctgc tcttgtgccg     2340

aggctgtcgg gctgtctcta gggtgggagc agctaatcag atcgcccagc ctttggccct     2400

cagaaaaagt gctgaaacgt gcccttgcac tggacgtcac agccctgcga gcatctgctg     2460

gactcaggcg tgctctttgc tggttcctgg gaggcttggc cacatccctc atggccccat     2520

tttatccccg aaatcctggg tgtgtcacca gtgtagaggg tggggaaggg gtgtctcacc     2580

tgagctgact ttgttcttcc ttcacaacct tctgagcctt ctttgggatt ctggaaggaa     2640

ctcggcgtga gaaacatgtg acttcccctt tcccttccca ctcgctgctt cccacagggt     2700

gacaggctgg gctggagaaa cagaaatcct caccctgcgt cttcccaagt tagcaggtgt     2760

ctctggtgtt cagtgaggag gacatgtgag tcctggcaga agccatggcc catgtctgca     2820

catccaggga ggaggacaga aggcccagct cacatgtgag tcctggcaga agccatggcc     2880

catgtctgca catccaggga ggaggacaga aggcccagct cacatgtgag tcctggcaga     2940

agccatggcc catgtctgca catccaggga ggaggacaga aggcccagct cagtggcccc     3000

cgccccccac cccccacgcc cgaacagcag gggcagagca gccctccttc gaagtgtgtc     3060

caagtccgca tttgagcctt gttctggggc ccagcccaac acctggcttg ggctcactgt     3120

cctgagttgc agtaaagcta taaccttgaa tcacaaaaaa aaaaaaaaaa aaaaaaaa       3178


<210>  2138
<211>  6780
<212>  DNA
<213>  homo sapiens

<400>  2138
gattgccacc caggacgatg agcggctgag atggagacgt ctgcctcagc cactgcctcc       60

gagaagcaag aagccaaaag tgggatcctg gaggccgctg gcttccccga cccgggtaaa      120

aaggcctctc ctttggtggt ggctgcagcg gcagcagcag cggtagctgc ccaaggagtg      180

ccgcagcatc tcttgccacc attccatgcg cccctaccga ttgacatgcg acaccaggaa      240

ggaaggtacc attacgagcc tcattctgtc cacggtgtgc acgggccccc tgccctcagc      300

ggcagccctg tcatctctga catctccttg atccggcttt ccccgcaccc ggctggccct      360

ggggagtccc ccttcaacgc cccccacccg tacgtgaacc cccacatgga gcactacctc      420

cgttctgtgc acagcagccc cacgctctcc atgatctctg cagccagggg cctcagcccc      480

gctgatgtgg cccaggagca ccttaaggag aggggactgt ttggccttcc tgctccaggc      540

accaccccct cagactatta ccaccagatg accctcgtgg caggccaccc cgcgccctac      600

ggggacctgc tgatgcagag cgggggcgct gccagcgcac cccatctcca cgactacctc      660

aaccccgtgg acgtgtcccg tttctccagc ccgcgggtga cgccccgcct gagccgcaag      720

cgggcgctgt ccatctcccc actctcagac gccagcctgg acctgcagcg gatgatccgc      780

acctcaccca actcgctagt ggcctacatc aacaactccc gaagcagctc ggcggccagc      840

ggttcctacg ggcatctgtc agcgggtgcc ctcagcccag ccttcacctt cccccacccc      900

atcaaccccg tggcctacca gcagattctg agccagcaga ggggtctggg gtcagccttt      960

ggacacacac cacccctgat ccagccctca cccaccttcc tggcccagca gcccatggcc     1020

ctcacctcca tcaatgccac gcccacccag ctcagcagca gcagcaactg tctgagtgac     1080

accaaccaga acaagcagag cagtgagtcg gccgtcagca gcaccgtcaa ccctgtcgcc     1140

attcacaagc gcagcaaggt caagaccgag cctgagggcc tgcggccggc ctcccctctg     1200

gcgctgacgc agggccaggt gtctggacac ggctcatgtg ggtgtgccct tcccctctcc     1260

caggagcagc tggctgacct caaggaagat ctggacaggg atgactgtaa gcaggaggct     1320

gaggtggtca tctatgagac caactgccac tgggaagact gcaccaagga gtacgacacc     1380

caggagcagc tggtgcatca catcaacaac gagcacatcc acggggagaa gaaggagttt     1440

gtgtgccgct ggcaggcctg cacgcgggag cagaagccct tcaaggcgca gtacatgctg     1500

gtggtgcaca tgcggcgaca cacgggcgag aagccccaca agtgcacgtt cgagggctgc     1560

tcgaaggcct actcccgcct ggagaacctg aagacacacc tgcggtccca caccggggag     1620

aagccatatg tgtgtgagca cgagggctgc aacaaagcct tctccaacgc ctcggaccgc     1680

gccaagcacc agaatcgcac ccactccaac gagaaaccct acatctgcaa gatcccaggc     1740

tgcaccaaga gatacacaga ccccagctct ctccggaagc atgtgaaaac ggtccacggc     1800

ccagatgccc acgtcaccaa gaagcagcgc aatgacgtgc acctccgcac accgctgctc     1860

aaagagaatg gggacagtga ggccggcacg gagcctggcg gcccagagag caccgaggcc     1920

agcagcacca gccaggccgt ggaggactgc ctgcacgtca gagccatcaa gaccgagagc     1980

tccgggctgt gtcagtccag ccccggggcc cagtcgtcct gcagcagcga gccctctcct     2040

ctgggcagtg cccccaacaa tgacagtggc gtggagatgc cggggacggg gcccgggagc     2100

ctgggagacc tgacggcact ggatgacaca cccccagggg ccgacacctc agccctggct     2160

gccccctccg ctggtggcct ccagctgcgc aaacacatga ccaccatgca ccggttcgag     2220

cagctcaaga aggagaagct caagtcactc aaggattcct gctcatgggc cgggccgact     2280

ccacacacgc ggaacaccaa gctgcctccc ctcccgggaa gtggctccat cctggaaaac     2340

ttcagtggca gtgggggcgg cgggcccgcg gggctgctgc cgaacccgcg gctgtcggag     2400

ctgtccgcga gcgaggtgac catgctgagc cagctgcagg agcgccgcga cagctccacc     2460

agcacggtca gctcggccta caccgtgagc cgccgctcct ccggcatctc cccctacttc     2520

tccagccgcc gctccagcga ggcctcgccc ctgggcgccg gccgcccgca caacgcgagc     2580

tccgctgact cctacgaccc catctccacg gacgcgtcgc ggcgctcgag cgaggccagc     2640

cagtgcagcg gcggctccgg gctgctcaac ctcacgccgg cgcagcagta cagcctgcgg     2700

gccaagtacg cggcagccac tggcggcccc ccgcccactc cgctgccggg cctggagcgc     2760

atgagcctgc ggaccaggct ggcgctgctg gacgcgcccg agcgcacgct gcccgccggc     2820

tgcccacgcc cactggggcc gcggcgtggc agcgacgggc cgacctatgg ccacggccac     2880

gcgggggctg cgcccgcctt cccccacgag gctccaggcg gcggagccag gcgggccagc     2940

gaccctgtgc ggcggcccga tgccctgtcc ctgccgcggg tgcagcgctt ccacagcacc     3000

cacaacgtga accccggccc gctgccgccc tgtgccgaca ggcgaggcct ccgcctgcag     3060

agccacccga gcaccgacgg cggcctggcc cgcggcgcct actcgccccg gccgcctagc     3120

atcagcgaga acgtggcgat ggaggccgtg gcggcaggag tggacggcgc ggggcccgag     3180

gccgacctgg ggctgccgga ggacgacctg gtgcttccag acgacgtggt gcagtacatc     3240

aaggcgcacg ccagtggcgc tctggacgag ggcaccgggc aggtgtatcc cacggaaagc     3300

actggcttct ctgacaaccc cagactaccc agcccggggc tgcacggcca gcgcaggatg     3360

gtggctgcgg actccaacgt gggcccctcc gcccctatgc tgggaggatg ccagttaggc     3420

tttggggcgc cctccagcct gaacaaaaat aacatgcctg tgcagtggaa tgaggtgagc     3480

tccggcaccg tagacgccct ggccagccag gtgaagcctc caccctttcc tcagggcaac     3540

ctggcggtgg tgcagcagaa gcctgccttt ggccagtacc cgggctacag tccgcaaggc     3600

ctacaggcta gccctggggg cctggacagc acgcagccac acctgcagcc ccgcagcgga     3660

gccccctccc agggcatccc cagggtaaac tacatgcagc agctgcgaca gccagtggca     3720

ggcagccagt gtcctggcat gactaccact atgagccccc atgcctgcta tggccaagtc     3780

cacccccagc tgagccccag caccatcagt ggggccctca accagttccc ccaatcctgc     3840

agcaacatgc cagccaagcc agggcatctg gggcaccctc agcagacaga agtggcacct     3900

gaccccacca cgatgggcaa tcgccacagg gaacttgggg tccccgattc agccctggct     3960

ggagtgccac cacctcaccc agtccagagc tacccacagc agagccatca cctggcagcc     4020

tccatgagcc aggagggcta ccaccaggtc cccagccttc tgcctgcccg ccagcctggc     4080

ttcatggagc cccaaacagg cccgatgggg gtggctacag caggctttgg cctagtgcag     4140

ccccggcctc ccctcgagcc cagccccact ggccgccacc gtggggtacg tgctgtgcag     4200

cagcagctgg cctacgccag ggccacaggc catgccatgg ctgccatgcc gtccagtcag     4260

gaaacagcag aggctgtgcc caagggagcg atgggcaaca tggggtcggt gcctccccag     4320

ccgcctccgc aggacgcagg tggggccccg gaccacagca tgctctacta ctacggccag     4380

atccacatgt acgaacagga tggaggcctg gagaacctcg ggagctgcca ggtcatgcgg     4440

tcccagccac cacagccaca ggcctgtcag gacagcatcc agccccagcc cttgccctca     4500

ccaggggtca accaggtgtc cagcactgtg gactcccagc tcctggaggc cccccagatt     4560

gacttcgatg ccatcatgga tgatggcgat cactcgagtt tgttctcggg tgctctgagc     4620

cccagcctcc tccacagcct ctcccagaac tcctcccgcc tcaccacccc ccgaaactcc     4680

ttgaccctgc cctccatccc cgcaggcatc agcaacatgg ctgtcgggga catgagctcc     4740

atgctcacca gcctcgccga ggagagcaag ttcctgaaca tgatgaccta gaggcccgag     4800

cgcctggtgc tgagtgcacc cggaggggtc atcgctgccc agagcctggg gattccagct     4860

gtcttgtctt tttccaaaaa agtgttaaat aggcttgagg ggttgttgcg caatggccgc     4920

ttcagatgac agatgttgta agagaaggtt tatgggcatc ctctctggtc ttttggatta     4980

ttcctcagaa caatgaaaaa agtctccata ggacaggaag gaatgcaaaa ctcatttaca     5040

cagtgctttc cagcctttgg tgcttacagg accgcgctgt tccggcttct tcacggctga     5100

cattcggcta acgagggatt actttggcca aaacctttca aaggatatgc agaaagatgg     5160

tagggagcat ttgggtttga atctgaatgc tatactggat actctgctcc ggaaagatga     5220

gctttttatt ctactacttg gaaggaaaag gaattcctgg tccacctgaa ttcctctatg     5280

aagcctaact cttgaggtct ctaacatacc ttgtcataga ggaaaagcac agattatacc     5340

tggatgattc aggagcacat tctgattcca ggtttggtag agctggctct tctactccgt     5400

aaagccgagt ctgggactgg cagcccatcc aagtgtatat gaatgaataa agcatccaag     5460

tatatatgaa tgaataaagt atgtaagtat caccagaaaa aggaaagaaa aaatgtactc     5520

cttggggcaa gcccagaagc tgccctggcc tctccagacc gtgtttacag tgtttgcatg     5580

tagaatgtag cccttcctga aaagaagact tgtttctaaa tacctcgggg ctgctggagc     5640

cgctgtgggt tagggatgga ctgaggcctc gaggagtgag ggtgcacccg gggcccagcc     5700

tcaggctgcc ctagggatct ctcagtagga agaggaagtt gcgtgtttac ccaatcctgt     5760

ttctccaatg caacgtccac ccactttacc accaaaaact ccagggcctg acggcagccc     5820

ggtcccccag cactcaccag cagcccagtg ttctccacca agccacagtg tgcatgcctg     5880

gtatcctccg gattcccttc cttctgcccg ctgagtcact gggcagagaa tgatgacatg     5940

tgtaggtggt gtggttgggg gtggaaaggg gaaggggttg atcctcagga ctctgaggga     6000

gcatcgttga attttcctgt tcagtgtgac caagacccac ctggaaatgg aatttggaac     6060

tggcttcagg agacatcatt cctgaacaca ctgtagggtg aattggtgca tcttccccac     6120

catacacaca cacacacaca cacacacaca cacacacaca cacacacccc aaaccttttc     6180

atggggaatg tgtggcaacc ttgccaaaca gcaccactca gagtgtgact ctgactgtga     6240

ccttggcctt aatgaggaac ttcttaggag agtttgagga caaggccaac atcgtcatct     6300

gggctcgctg cgtcccagca catcaaactc tgtccagaga caaggccaac tgcaaatgaa     6360

agccagggaa cattgctaag ggtctgtggc tctgtggtgg tgttcatcgc cttcctgaga     6420

taggatttcc cttgccagtc ccaacctgta tatattctgt acagaagaca tccctgaata     6480

tactgtaggt gagtcgtcca gccaaattta tatctccaaa acatttttag ctttttctac     6540

atgctatgaa ttgagatgac atgctcaact tgtaaataag tctttttgta cattaaaaaa     6600

gtaatttttt cataatttat cttgtctatc tgcttccccc ttgacagtag ttaatgagaa     6660

cctgggcagt aaatttggtg cattcgagca gaaattaggc tgtatttttt cttaacagtg     6720

tcaaaattga ctatcccgcc tttgccaaga aatgtttaat gctgaggcaa aaaaaaaaaa     6780


<210>  2139
<211>  6780
<212>  DNA
<213>  homo sapiens

<400>  2139
gattgccacc caggacgatg agcggctgag atggagacgt ctgcctcagc cactgcctcc       60

gagaagcaag aagccaaaag tgggatcctg gaggccgctg gcttccccga cccgggtaaa      120

aaggcctctc ctttggtggt ggctgcagcg gcagcagcag cggtagctgc ccaaggagtg      180

ccgcagcatc tcttgccacc attccatgcg cccctaccga ttgacatgcg acaccaggaa      240

ggaaggtacc attacgagcc tcattctgtc cacggtgtgc acgggccccc tgccctcagc      300

ggcagccctg tcatctctga catctccttg atccggcttt ccccgcaccc ggctggccct      360

ggggagtccc ccttcaacgc cccccacccg tacgtgaacc cccacatgga gcactacctc      420

cgttctgtgc acagcagccc cacgctctcc atgatctctg cagccagggg cctcagcccc      480

gctgatgtgg cccaggagca ccttaaggag aggggactgt ttggccttcc tgctccaggc      540

accaccccct cagactatta ccaccagatg accctcgtgg caggccaccc cgcgccctac      600

ggggacctgc tgatgcagag cgggggcgct gccagcgcac cccatctcca cgactacctc      660

aaccccgtgg acgtgtcccg tttctccagc ccgcgggtga cgccccgcct gagccgcaag      720

cgggcgctgt ccatctcccc actctcagac gccagcctgg acctgcagcg gatgatccgc      780

acctcaccca actcgctagt ggcctacatc aacaactccc gaagcagctc ggcggccagc      840

ggttcctacg ggcatctgtc agcgggtgcc ctcagcccag ccttcacctt cccccacccc      900

atcaaccccg tggcctacca gcagattctg agccagcaga ggggtctggg gtcagccttt      960

ggacacacac cacccctgat ccagccctca cccaccttcc tggcccagca gcccatggcc     1020

ctcacctcca tcaatgccac gcccacccag ctcagcagca gcagcaactg tctgagtgac     1080

accaaccaga acaagcagag cagtgagtcg gccgtcagca gcaccgtcaa ccctgtcgcc     1140

attcacaagc gcagcaaggt caagaccgag cctgagggcc tgcggccggc ctcccctctg     1200

gcgctgacgc agggccaggt gtctggacac ggctcatgtg ggtgtgccct tcccctctcc     1260

caggagcagc tggctgacct caaggaagat ctggacaggg atgactgtaa gcaggaggct     1320

gaggtggtca tctatgagac caactgccac tgggaagact gcaccaagga gtacgacacc     1380

caggagcagc tggtgcatca catcaacaac gagcacatcc acggggagaa gaaggagttt     1440

gtgtgccgct ggcaggcctg cacgcgggag cagaagccct tcaaggcgca gtacatgctg     1500

gtggtgcaca tgcggcgaca cacgggcgag aagccccaca agtgcacgtt cgagggctgc     1560

tcgaaggcct actcccgcct ggagaacctg aagacacacc tgcggtccca caccggggag     1620

aagccatatg tgtgtgagca cgagggctgc aacaaagcct tctccaacgc ctcggaccgc     1680

gccaagcacc agaatcgcac ccactccaac gagaaaccct acatctgcaa gatcccaggc     1740

tgcaccaaga gatacacaga ccccagctct ctccggaagc atgtgaaaac ggtccacggc     1800

ccagatgccc acgtcaccaa gaagcagcgc aatgacgtgc acctccgcac accgctgctc     1860

aaagagaatg gggacagtga ggccggcacg gagcctggcg gcccagagag caccgaggcc     1920

agcagcacca gccaggccgt ggaggactgc ctgcacgtca gagccatcaa gaccgagagc     1980

tccgggctgt gtcagtccag ccccggggcc cagtcgtcct gcagcagcga gccctctcct     2040

ctgggcagtg cccccaacaa tgacagtggc gtggagatgc cggggacggg gcccgggagc     2100

ctgggagacc tgacggcact ggatgacaca cccccagggg ccgacacctc agccctggct     2160

gccccctccg ctggtggcct ccagctgcgc aaacacatga ccaccatgca ccggttcgag     2220

cagctcaaga aggagaagct caagtcactc aaggattcct gctcatgggc cgggccgact     2280

ccacacacgc ggaacaccaa gctgcctccc ctcccgggaa gtggctccat cctggaaaac     2340

ttcagtggca gtgggggcgg cgggcccgcg gggctgctgc cgaacccgcg gctgtcggag     2400

ctgtccgcga gcgaggtgac catgctgagc cagctgcagg agcgccgcga cagctccacc     2460

agcacggtca gctcggccta caccgtgagc cgccgctcct ccggcatctc cccctacttc     2520

tccagccgcc gctccagcga ggcctcgccc ctgggcgccg gccgcccgca caacgcgagc     2580

tccgctgact cctacgaccc catctccacg gacgcgtcgc ggcgctcgag cgaggccagc     2640

cagtgcagcg gcggctccgg gctgctcaac ctcacgccgg cgcagcagta cagcctgcgg     2700

gccaagtacg cggcagccac tggcggcccc ccgcccactc cgctgccggg cctggagcgc     2760

atgagcctgc ggaccaggct ggcgctgctg gacgcgcccg agcgcacgct gcccgccggc     2820

tgcccacgcc cactggggcc gcggcgtggc agcgacgggc cgacctatgg ccacggccac     2880

gcgggggctg cgcccgcctt cccccacgag gctccaggcg gcggagccag gcgggccagc     2940

gaccctgtgc ggcggcccga tgccctgtcc ctgccgcggg tgcagcgctt ccacagcacc     3000

cacaacgtga accccggccc gctgccgccc tgtgccgaca ggcgaggcct ccgcctgcag     3060

agccacccga gcaccgacgg cggcctggcc cgcggcgcct actcgccccg gccgcctagc     3120

atcagcgaga acgtggcgat ggaggccgtg gcggcaggag tggacggcgc ggggcccgag     3180

gccgacctgg ggctgccgga ggacgacctg gtgcttccag acgacgtggt gcagtacatc     3240

aaggcgcacg ccagtggcgc tctggacgag ggcaccgggc aggtgtatcc cacggaaagc     3300

actggcttct ctgacaaccc cagactaccc agcccggggc tgcacggcca gcgcaggatg     3360

gtggctgcgg actccaacgt gggcccctcc gcccctatgc tgggaggatg ccagttaggc     3420

tttggggcgc cctccagcct gaacaaaaat aacatgcctg tgcagtggaa tgaggtgagc     3480

tccggcaccg tagacgccct ggccagccag gtgaagcctc caccctttcc tcagggcaac     3540

ctggcggtgg tgcagcagaa gcctgccttt ggccagtacc cgggctacag tccgcaaggc     3600

ctacaggcta gccctggggg cctggacagc acgcagccac acctgcagcc ccgcagcgga     3660

gccccctccc agggcatccc cagggtaaac tacatgcagc agctgcgaca gccagtggca     3720

ggcagccagt gtcctggcat gactaccact atgagccccc atgcctgcta tggccaagtc     3780

cacccccagc tgagccccag caccatcagt ggggccctca accagttccc ccaatcctgc     3840

agcaacatgc cagccaagcc agggcatctg gggcaccctc agcagacaga agtggcacct     3900

gaccccacca cgatgggcaa tcgccacagg gaacttgggg tccccgattc agccctggct     3960

ggagtgccac cacctcaccc agtccagagc tacccacagc agagccatca cctggcagcc     4020

tccatgagcc aggagggcta ccaccaggtc cccagccttc tgcctgcccg ccagcctggc     4080

ttcatggagc cccaaacagg cccgatgggg gtggctacag caggctttgg cctagtgcag     4140

ccccggcctc ccctcgagcc cagccccact ggccgccacc gtggggtacg tgctgtgcag     4200

cagcagctgg cctacgccag ggccacaggc catgccatgg ctgccatgcc gtccagtcag     4260

gaaacagcag aggctgtgcc caagggagcg atgggcaaca tggggtcggt gcctccccag     4320

ccgcctccgc aggacgcagg tggggccccg gaccacagca tgctctacta ctacggccag     4380

atccacatgt acgaacagga tggaggcctg gagaacctcg ggagctgcca ggtcatgcgg     4440

tcccagccac cacagccaca ggcctgtcag gacagcatcc agccccagcc cttgccctca     4500

ccaggggtca accaggtgtc cagcactgtg gactcccagc tcctggaggc cccccagatt     4560

gacttcgatg ccatcatgga tgatggcgat cactcgagtt tgttctcggg tgctctgagc     4620

cccagcctcc tccacagcct ctcccagaac tcctcccgcc tcaccacccc ccgaaactcc     4680

ttgaccctgc cctccatccc cgcaggcatc agcaacatgg ctgtcgggga catgagctcc     4740

atgctcacca gcctcgccga ggagagcaag ttcctgaaca tgatgaccta gaggcccgag     4800

cgcctggtgc tgagtgcacc cggaggggtc atcgctgccc agagcctggg gattccagct     4860

gtcttgtctt tttccaaaaa agtgttaaat aggcttgagg ggttgttgcg caatggccgc     4920

ttcagatgac agatgttgta agagaaggtt tatgggcatc ctctctggtc ttttggatta     4980

ttcctcagaa caatgaaaaa agtctccata ggacaggaag gaatgcaaaa ctcatttaca     5040

cagtgctttc cagcctttgg tgcttacagg accgcgctgt tccggcttct tcacggctga     5100

cattcggcta acgagggatt actttggcca aaacctttca aaggatatgc agaaagatgg     5160

tagggagcat ttgggtttga atctgaatgc tatactggat actctgctcc ggaaagatga     5220

gctttttatt ctactacttg gaaggaaaag gaattcctgg tccacctgaa ttcctctatg     5280

aagcctaact cttgaggtct ctaacatacc ttgtcataga ggaaaagcac agattatacc     5340

tggatgattc aggagcacat tctgattcca ggtttggtag agctggctct tctactccgt     5400

aaagccgagt ctgggactgg cagcccatcc aagtgtatat gaatgaataa agcatccaag     5460

tatatatgaa tgaataaagt atgtaagtat caccagaaaa aggaaagaaa aaatgtactc     5520

cttggggcaa gcccagaagc tgccctggcc tctccagacc gtgtttacag tgtttgcatg     5580

tagaatgtag cccttcctga aaagaagact tgtttctaaa tacctcgggg ctgctggagc     5640

cgctgtgggt tagggatgga ctgaggcctc gaggagtgag ggtgcacccg gggcccagcc     5700

tcaggctgcc ctagggatct ctcagtagga agaggaagtt gcgtgtttac ccaatcctgt     5760

ttctccaatg caacgtccac ccactttacc accaaaaact ccagggcctg acggcagccc     5820

ggtcccccag cactcaccag cagcccagtg ttctccacca agccacagtg tgcatgcctg     5880

gtatcctccg gattcccttc cttctgcccg ctgagtcact gggcagagaa tgatgacatg     5940

tgtaggtggt gtggttgggg gtggaaaggg gaaggggttg atcctcagga ctctgaggga     6000

gcatcgttga attttcctgt tcagtgtgac caagacccac ctggaaatgg aatttggaac     6060

tggcttcagg agacatcatt cctgaacaca ctgtagggtg aattggtgca tcttccccac     6120

catacacaca cacacacaca cacacacaca cacacacaca cacacacccc aaaccttttc     6180

atggggaatg tgtggcaacc ttgccaaaca gcaccactca gagtgtgact ctgactgtga     6240

ccttggcctt aatgaggaac ttcttaggag agtttgagga caaggccaac atcgtcatct     6300

gggctcgctg cgtcccagca catcaaactc tgtccagaga caaggccaac tgcaaatgaa     6360

agccagggaa cattgctaag ggtctgtggc tctgtggtgg tgttcatcgc cttcctgaga     6420

taggatttcc cttgccagtc ccaacctgta tatattctgt acagaagaca tccctgaata     6480

tactgtaggt gagtcgtcca gccaaattta tatctccaaa acatttttag ctttttctac     6540

atgctatgaa ttgagatgac atgctcaact tgtaaataag tctttttgta cattaaaaaa     6600

gtaatttttt cataatttat cttgtctatc tgcttccccc ttgacagtag ttaatgagaa     6660

cctgggcagt aaatttggtg cattcgagca gaaattaggc tgtatttttt cttaacagtg     6720

tcaaaattga ctatcccgcc tttgccaaga aatgtttaat gctgaggcaa aaaaaaaaaa     6780


<210>  2140
<211>  8573
<212>  DNA
<213>  homo sapiens

<400>  2140
gagtagctcc agcggccacg ctgaggcgag ggtgacacac catgctcacg gcccctggag       60

accgtcgtgc tggcgagccg tgctccgtag ctccccggtc cgcctcggca gcggtcagag      120

tcgcctacag gagttgagcc gcccgcgcca gaaggttttg gcgaagctct tggagaggcg      180

tcgagcacag tagggcggcg ggggtgcgtt gagcgctcgg gggtcaggca gtcggccggg      240

atcgccgctg gggagcgttt ccgaggcgag gaggaggagg aggagatgct gctcctcttc      300

tccccctccc caggctcctt ctacagctcc ttcagcccac gcccgcagcc gcttgtggga      360

gaagtggtgg tggctctcgg cgcccgcggc ggctgccggc ggcccgcccc gacgccgcgt      420

ccctgcagcc ctcgcccggc gctccagtag caggacccgg tctcgggacc agccggtaat      480

atgcacgtgt cactagctga ggccctggag gttcggggtg gaccacttca ggaggaagaa      540

atatgggctg tattaaatca aagtgctgaa agtctccaag aattattcag aaaagtaagc      600

ctagctgatc ctgctgccct tggcttcatc atttctccat ggtctctgct gttgctgcca      660

tctggtagtg tgtcatttac agatgaaaat atttccaatc aggatcttcg agcattcact      720

gcaccagagg ttcttcaaaa tcagtcacta acttctctct cagatgttga aaagatccac      780

atttattctc ttggaatgac actgtattgg ggggctgatt atgaagtgcc tcagagccaa      840

cctattaagc ttggagatca tctcaacagc atactgcttg gaatgtgtga ggatgttatt      900

tacgctcgag tttctgttcg gactgtgctg gatgcttgca gtgcccacat taggaatagc      960

aattgtgcac cctcattttc ctacgtgaaa cacttggtaa aactggttct gggaaatctt     1020

tctgggacag atcagctttc ctgtaacagt gaacaaaagc ctgatcgaag ccaggctatt     1080

cgagatcgat tgcgaggaaa aggattacca acaggaagaa gctctacttc tgatgtacta     1140

gacatacaaa agcctccact ctctcatcag acctttctta acaaagggct tagtaaatct     1200

atgggatttc tgtccatcaa agatacacaa gatgagaatt atttcaagga cattttatca     1260

gataattctg gacgtgaaga ttctgaaaat acattctccc cttaccagtt caaaactagt     1320

ggcccagaaa aaaaacccat ccctggcatt gatgtgcttt ctaagaagaa gatctgggct     1380

tcatccatgg acttgctttg tacagctgac agagacttct cttcaggaga gactgccaca     1440

tatcgtcgtt gtcaccctga ggcagtaaca gtgcggactt caactactcc tagaaaaaag     1500

gaggcaagat actcagatgg aagtatagcc ttggatatct ttggccctca gaaaatggat     1560

ccaatatatc acactcgaga attgcccacc tcctcagcaa tatcaagtgc tttggaccga     1620

atccgagaga gacaaaagaa acttcaggtt ctgagggaag ccatgaatgt agaagaacca     1680

gttcgaagat acaaaactta tcatggtgat gtctttagta cctccagtga aagtccatct     1740

attatttcct ctgaatcaga tttcagacaa gtgagaagaa gtgaagcctc aaagaggttt     1800

gaatccagca gtggtctccc aggggtagat gaaaccttaa gtcaaggcca gtcacagaga     1860

ccgagcagac aatatgaaac accctttgaa ggcaacttaa ttaatcaaga gatcatgcta     1920

aaacggcaag aggaagaact gatgcagcta caagccaaaa tggcccttag acagtctcgg     1980

ttgagcctat atccaggaga cacaatcaaa gcgtccatgc ttgacatcac cagggatccg     2040

ttaagagaaa ttgccctaga aacagccatg actcaaagaa aactgaggaa tttctttggc     2100

cctgagtttg tgaaaatgac aattgaacca tttatatctt tggatttgcc acggtctatt     2160

cttactaaga aagggaagaa tgaggataac cgaaggaaag taaacataat gcttctgaac     2220

gggcaaagac tggaactgac ctgtgatacc aaaactatat gtaaagatgt gtttgatatg     2280

gttgtggcac atattggctt agtagagcat catttgtttg ctttagctac cctcaaagat     2340

aatgaatatt tctttgttga tcctgactta aaattaacca aagtggcccc agagggatgg     2400

aaagaagaac caaagaaaaa gaccaaagcc actgttaatt ttactttgtt tttcagaatt     2460

aaatttttta tggatgatgt tagtctaata caacatactc tgacgtgtca tcagtattac     2520

cttcagcttc gaaaagatat tttggaggaa aggatgcact gtgatgatga gacttcctta     2580

ttgctggcat ccttggctct ccaggctgag tatggagatt atcaaccaga ggttcatggt     2640

gtgtcttact ttagaatgga gcactatttg cccgccagag tgatggagaa acttgattta     2700

tcctatatca aagaagagtt acccaaattg cataatacct atgtgggagc ttctgaaaaa     2760

gagacagagt tagaattttt aaaggtctgc caaagactga cagaatatgg agttcatttt     2820

caccgagtgc accctgagaa gaagtcacaa acaggaatat tgcttggagt ctgttctaaa     2880

ggtgtccttg tgtttgaagt tcacaatgga gtgcgcacat tggtccttcg ctttccatgg     2940

agggaaacca agaaaatatc tttttctaaa aagaaaatca cattgcaaaa tacatcagat     3000

ggaataaaac atggcttcca gacagacaac agtaagatat gccagtacct gctgcacctc     3060

tgctcttacc agcataagtt ccagctacag atgagagcaa gacagagcaa ccaagatgcc     3120

caagatattg agagagcttc gtttaggagc ctgaatctcc aagcagagtc tgttagagga     3180

tttaatatgg gacgagcaat cagcactggc agtctggcca gcagcaccct caacaaactt     3240

gctgttcgac ctttatcagt tcaagctgag attctgaaga ggctatcctg ctcagagctg     3300

tcgctttacc agccattgca aaacagttca aaagagaaga atgacaaagc ttcatgggag     3360

gaaaagccta gagagatgag taaatcatac catgatctca gtcaggcctc tctctatcca     3420

catcggaaaa atgtcattgt taacatggaa cccccaccac aaaccgttgc agagttggtg     3480

ggaaaacctt ctcaccagat gtcaagatct gatgcagaat ctttggcagg agtgacaaaa     3540

cttaataatt caaagtctgt tgcgagttta aatagaagtc ctgaaaggag gaaacatgaa     3600

tcagactcct catccattga agaccctggg caagcatatg ttctaggaat gactatgcat     3660

agttctggaa actcttcatc ccaagtaccc ttaaaagaaa atgatgtgct acacaaaaga     3720

tggagcatag tatcttcacc agaaagggag atcaccttag tgaacctgaa aaaagatgca     3780

aagtatggct tgggatttca aattattggt ggggagaaga tgggaagact ggacctaggc     3840

atatttatca gttcagttgc ccctggagga ccagctgact tggatggatg cttgaagcca     3900

ggagaccgtt tgatatctgt gaatagtgtg agtctggagg gagtcagcca ccatgctgca     3960

attgaaattt tgcaaaatgc acctgaagat gtgacacttg ttatctctca gccaaaagaa     4020

aagatatcca aagtgccttc tactcctgtg catctcacca atgagatgaa aaactacatg     4080

aagaaatctt cctacatgca agacagtgct atagattctt cttccaagga tcaccactgg     4140

tcacgtggta ccctgaggca catctcggag aactcctttg ggccatctgg gggcctgcgg     4200

gaaggaagcc tgagttctca agattccagg actgagagtg ccagcttgtc tcaaagccag     4260

gtcaatggtt tctttgccag ccatttaggt gaccaaacct ggcaggaatc acagcatggc     4320

agcccttccc catctgtaat atccaaagcc accgagaaag agactttcac tgatagtaac     4380

caaagcaaaa ctaaaaagcc aggcatttct gatgtaactg attactcaga ccgtggagat     4440

tcagacatgg atgaagccac ttactccagc agtcaggatc atcaaacacc aaaacaggaa     4500

tcttcctctt cagtgaatac atccaacaag atgaatttta aaactttttc ttcatcacct     4560

cctaagcctg gagatatctt tgaggttgaa ctggctaaaa atgataacag cttggggata     4620

agtgtcacgg gaggtgtgaa tacgagtgtc agacatggtg gcatttatgt gaaagctgtt     4680

attccccagg gagcagcaga gtctgatggt agaattcaca aaggtgatcg cgtcctagct     4740

gtcaatggag ttagtctaga aggagccacc cataagcaag ctgtggaaac actgagaaat     4800

acaggacagg tggttcatct gttattagaa aagggacaat ctccaacatc taaagaacat     4860

gtcccggtaa ccccacagtg taccctttca gatcagaatg cccaaggtca aggcccagaa     4920

aaagtgaaga aaacaactca ggtcaaagac tacagctttg tcactgaaga aaatacattt     4980

gaggtaaaat tatttaaaaa tagctcaggt ctaggattca gtttttctcg agaagataat     5040

cttataccgg agcaaattaa tgccagcata gtaagggtta aaaagctctt tcctggacag     5100

ccagcagcag aaagtggaaa aattgatgta ggagatgtta tcttgaaagt gaatggagcc     5160

tctttgaaag gactatctca gcaggaagtc atatctgctc tcaggggaac tgctccagaa     5220

gtattcttgc ttctctgcag acctccacct ggtgtgctac cggaaattga tactgcgctt     5280

ttgaccccac ttcagtctcc agcacaagta cttccaaaca gcagtaaaga ctcttctcag     5340

ccatcatgtg tggagcaaag caccagctca gatgaaaatg aaatgtcaga caaaagcaaa     5400

aaacagtgca agtccccatc cagaagagac agttacagtg acagcagtgg gagtggagaa     5460

gatgacttag tgacagctcc agcaaacata tcaaattcga cctggagttc agctttgcat     5520

cagactctaa gcaacatggt atcacaggca cagagtcatc atgaagcacc caagagtcaa     5580

gaagatacca tttgtaccat gttttactat cctcagaaaa ttcccaataa accagagttt     5640

gaggacagta atccttcccc tctaccaccg gatatggctc ctgggcagag ttatcaaccc     5700

caatcagaat ctgcttcctc tagttcgatg gataagtatc atatacatca catttctgaa     5760

ccaactagac aagaaaactg gacacctttg aaaaatgact tggaaaatca ccttgaagac     5820

tttgaactgg aagtagaact cctcattacc ctaattaaat cagaaaaagg aagcctgggt     5880

tttacagtaa ccaaaggcaa tcagagaatt ggttgttatg ttcatgatgt catacaggat     5940

ccagccaaaa gtgatggaag gctaaaacct ggggaccggc tcataaaggt taatgataca     6000

gatgttacta atatgactca tacagatgca gttaatctgc tccgggctgc atccaaaaca     6060

gtcagattag ttattggacg agttctagaa ttacccagaa taccaatgtt gcctcatttg     6120

ctaccggaca taacactaac gtgcaacaaa gaggagttgg gtttttcctt atgtggaggt     6180

catgacagcc tttatcaagt ggtatatatt agtgatatta atccaaggtc cgtcgcagcc     6240

attgagggta atctccagct attagatgtc atccattatg tgaacggagt cagcacacaa     6300

ggaatgacct tggaggaagt taacagagca ttagacatgt cacttccttc attggtattg     6360

aaagcaacaa gaaatgatct tccagtggtc cccagctcaa agaggtctgc tgtttcagct     6420

ccaaagtcaa ccaaaggcaa tggttcctac agtgtggggt cttgcagcca gcctgccctc     6480

actcctaatg attcattctc cacggttgct ggggaagaaa taaatgaaat atcgtacccc     6540

aaaggaaaat gttctactta tcagataaag ggatcaccaa acttgactct gcccaaagaa     6600

tcttatatac aagaagatga catttatgat gattcccaag aagctgaagt tatccagtct     6660

ctgctggatg ttgtggatga ggaagcccag aatcttttaa acgaaaataa tgcagcagga     6720

tactcctgtg gtccaggtac attaaagatg aatgggaagt tatcagaaga gagaacagaa     6780

gatacagact gcgatggttc acctttacct gagtatttta ctgaggccac caaaatgaat     6840

ggctgtgaag aatattgtga agaaaaagta aaaagtgaaa gcttaattca gaagccacaa     6900

gaaaagaaga ctgatgatga tgaaataaca tggggaaatg atgagttgcc aatagagaga     6960

acaaaccatg aagattctga taaagatcat tcctttctga caaacgatga gctcgctgta     7020

ctccctgtcg tcaaagtgct tccctctggt aaatacacgg gtgccaactt aaaatcagtc     7080

attcgagtcc tgcggggttt gctagatcaa ggaattcctt ctaaggagct ggagaatctt     7140

caagaattaa aacctttgga tcagtgtcta attgggcaaa ctaaggaaaa cagaaggaag     7200

aacagatata aaaatatact tccctatgat gctacaagag tgcctcttgg agatgaaggt     7260

ggctatatca atgccagctt cattaagata ccagttggga aagaagagtt cgtttacatt     7320

gcctgccaag gaccactgcc tacaactgtt ggagacttct ggcagatgat ttgggagcaa     7380

aaatccacag tgatagccat gatgactcaa gaagtagaag gagaaaaaat caaatgccag     7440

cgctattggc ccaacatcct aggcaaaaca acaatggtca gcaacagact tcgactggct     7500

cttgtgagaa tgcagcagct gaagggcttt gtggtgaggg caatgaccct tgaagatatt     7560

cagaccagag aggtgcgcca tatttctcat ctgaatttca ctgcctggcc agaccatgat     7620

acaccttctc aaccagatga tctgcttact tttatctcct acatgagaca catccacaga     7680

tcaggcccaa tcattacgca ctgcagtgct ggcattggac gttcagggac cctgatttgc     7740

atagatgtgg ttctgggatt aatcagtcag gatcttgatt ttgacatctc tgatttggtg     7800

cgctgcatga gactacaaag acacggaatg gttcagacag aggatcaata tattttctgc     7860

tatcaagtca tcctttatgt cctgacacgt cttcaagcag aagaagagca aaaacagcag     7920

cctcagcttc tgaagtgaca tgaaaagagc ctctggatgc atttccattt ctctccttaa     7980

cctccagcag actcctgctc tctatccaaa ataaagatca cagagcagca agttcataca     8040

acatgcatgt tctcctctat cttagagggg tattcttctt gaaaataaaa aatattgaaa     8100

tgctgtattt ttacagctac tttaacctat gataattatt tacaaaattt taacactaac     8160

caaacaatgc agatcttagg gatgattaaa ggcagcattt gatgatagca gacattgtta     8220

caaggacatg gtgagtctat ttttaatgca ccaatcttgt ttatagcaaa aatgttttcc     8280

aatattttaa taaagtagtt attttatagg ggatacttga aaccagtatt taagctttaa     8340

atgacagtaa tattggcata gaaaaaagta gcaaatgttt actgtatcaa tttctaatgt     8400

ttactatata gaatttcctg taatatattt atatactttt tcatgaaaat ggagttatca     8460

gttatctgtt tgttactgca tcatctgttt gtaatcatta tctcactttg taaataaaaa     8520

cacaccttaa aacatgaaca agccaaaact gtgtgcagac aaaaaaaaaa aaa            8573


<210>  2141
<211>  1591
<212>  DNA
<213>  homo sapiens

<400>  2141
agagccagcg gacggaacca ttccaaacag cctagtctcg tgctgagagc ctctccggtt       60

tcacgctgag acccgctcac ccccgctctg gccccttaga tgctattttg gcccgagtgt      120

cacgtcgggc gctctttaga gaggactggg acaagagttg cggacgcgaa gaacgagtaa      180

gcggtggttc atccctcctg accccacccc cgtggcctgg cccgatggtc gcgcccgggg      240

ttgcgagatt tgcgcctgcg cagtgcggcg cctagaggga aagcgagagg gagacggacg      300

ttgagagaac gaggaggaag gagagaaaat ggcgtccacg gattacagta cctatagcca      360

agctgcagcg cagcagggct acagtgctta caccgcccag cccactcaag gatatgcaca      420

gaccacccag gcatatgggc aacaaagcta tggaacctat ggacagccca ctgatgtcag      480

ctatacccag gctcagacca ctgcaaccta tgggcagacc gcctatgcaa cttcttatgg      540

acagcctccc actggttata ctactccaac tgccccccag gcatacagcc agcctgtcca      600

ggggtatggc actggtgctt atgataccac cactgctaca gtcaccacca cccaggcctc      660

ctatgcagct cagtctgcat atggcactca gcctgcttat ccagcctatg ggcagcagcc      720

agcagccact gcacctacaa gaccgcagga tggaaacaag cccactgaga ctagtcaacc      780

tcaatctagc acagggggtt acaaccagcc cagcctagga tatggacaga gtaactacag      840

ttatccccag gtacctggga gctaccccat gcagccagtc actgcacctc catcctaccc      900

tcctaccagc tattcctcta cacagccgac tagttatgat cagagcagtt actctcagca      960

gaacacctat gggcaaccga gcagctatgg acagcagagt agctatggtc aacaaagcag     1020

ctatgggcag cagcctccca ctagttaccc accccaaact ggatcctaca gccaagctcc     1080

aagtcaatat agccaacaga gcagcagcta cgggcagcag agttcattcc gacaggacca     1140

ccccagtagc atgggtgttt atgggcagga gtctggagga ttttccggac caggagagaa     1200

ccggagcatg agtggccctg ataaccgggg caggggaaga gggggatttg atcgtggagg     1260

catgagcaga ggtgggcggg gaggaggacg cggtggaatg gggttacaaa gtgagagcct     1320

tgtatacact tcaatactta aaaagtaccc gtactcagta ctcagccggc agcataatga     1380

aaagtgggac tagacacggt gtccatatgg agaggaaaaa tatacataga atatttttaa     1440

caaaatgtat tcattgtata aatggaatcc ttctgtaact ttggtaactg catacttgtt     1500

gtttggtaat gaaccagagg aggtataata ctctagaatt gtgtaacatt aaagtgtaaa     1560

cttttgtgtt taaaaaaaaa aaaaaaaaaa a                                    1591


<210>  2142
<211>  3934
<212>  DNA
<213>  homo sapiens

<400>  2142
ctccttcctg caagaagcgt tgcccgttgg ctagctgctc ggtggggatc tgcctgccct       60

gggggcgccg cccgcgctcc ccgcggtgct ctcgctcctg ggctgcgcca gtccgaggcg      120

gtgccggctc ctttgcctcc ccgagtcgca gatgctgcgg gcgcctccgg gaaaagatct      180

gggcggcgcg ctcgctcgat ggacacagga agatccagaa gctagtggca catctagcaa      240

cagagccaga tcagaaccca gatgctaaac tcctggtgga ctgcagagga gagggattca      300

gtcttctcct gatgtcgatt gcgatttctg ctgggagctc aagacgggcg agctgcccga      360

gatctcttcg agatacccca ggggaggagg agatgggcag gatttagtag gacaactcgg      420

ttactaatga cttggcggct ggctgcgacc ccccgggaaa tcaggtttgc ctgtaggtac      480

ctgagttgac accgaaggtg cctaaagatg ctgagcggcg tttggttcct cagtgtgtta      540

accgtggccg ggatcttaca gacagagagt cgcaaaactg ccaaagacat ttgcaagatc      600

cgctgtctgt gcgaagaaaa ggaaaacgta ctgaatatca actgtgagaa caaaggattt      660

acaacagtta gcctgctcca gcccccccag tatcgaatct atcagctttt tctcaatgga      720

aacctcttga caagactgta tccaaacgaa tttgtcaatt actccaacgc ggtgactctt      780

cacctaggta acaacgggtt acaggagatc cgaacggggg cattcagtgg cctgaaaact      840

ctcaaaagac tgcatctcaa caacaacaag cttgagatat tgagggagga caccttccta      900

ggcctggaga gcctggagta tctccaggcc gactacaatt acatcagtgc catcgaggct      960

ggggcattca gcaaacttaa caagctcaaa gtgctcatcc tgaatgacaa ccttctgctt     1020

tcactgccca gcaatgtgtt ccgctttgtc ctgctgaccc acttagacct cagggggaat     1080

aggctaaaag taatgccttt tgctggcgtc cttgaacata ttggagggat catggagatt     1140

cagctggagg aaaatccatg gaattgcact tgtgacttac ttcctctcaa ggcctggcta     1200

gacaccataa ctgtttttgt gggagagatt gtctgtgaga ctccctttag gttgcatggg     1260

aaagacgtga cccagctgac caggcaagac ctctgtccca gaaaaagtgc cagtgattcc     1320

agtcagaggg gcagccatgc tgacacccac gtccaaaggc tgtcacctac aatgaatcct     1380

gctctcaacc caaccagggc tccgaaagcc agccggccgc ccaaaatgag aaatcgtcca     1440

actcctcgag tgactgtgtc aaaggacagg caaagttttg gacccatcat ggtgtaccag     1500

accaagtctc ctgtgcctct cacctgtccc agcagctgtg tctgcacctc tcagagctca     1560

gacaatggtc tgaatgtaaa ctgccaagaa aggaagttca ctaatatctc tgacctgcag     1620

cccaaaccga ccagtccaaa gaaactctac ctaacaggga actatcttca aactgtctat     1680

aagaatgacc tcttagaata cagttctttg gacttactgc acttaggaaa caacaggatt     1740

gcagtcattc aggaaggtgc ctttacaaac ctgaccagtt tacgcagact ttatctgaat     1800

ggcaattacc ttgaagtgct gtacccttct atgtttgatg gactgcagag cttgcaatat     1860

ctctatttag agtataatgt cattaaggaa attaagcctc tgacctttga tgctttgatt     1920

aacctacagc tactgtttct gaacaacaac cttcttcggt ccttacctga taatatattt     1980

ggggggacgg ccctaaccag gctgaatctg agaaacaacc atttttctca cctgcccgtg     2040

aaaggggttc tggatcagct cccggctttc atccagatag atctgcagga gaacccctgg     2100

gactgtacct gtgacatcat ggggctgaaa gactggacag aacatgccaa ttcccctgtc     2160

atcattaatg aggtgacttg cgaatctcct gctaagcatg caggggagat actaaaattt     2220

ctggggaggg aggctatctg tccagacagc ccaaacttgt cagatggaac cgtcttgtca     2280

atgaatcaca atacagacac acctcggtcg cttagtgtgt ctcctagttc ctatcctgaa     2340

ctacacactg aagttccact gtctgtctta attctgggat tgcttgttgt tttcatctta     2400

tctgtctgtt ttggggctgg tttattcgtc tttgtcttga aacgccgaaa gggagtgccg     2460

agcgttccca ggaataccaa caacttagac gtaagctcct ttcaattaca gtatgggtct     2520

tacaacactg agactcacga taaaacagac ggccatgtct acaactatat ccccccacct     2580

gtgggtcaga tgtgccaaaa ccccatctac atgcagaagg aaggagaccc agtagcctat     2640

taccgaaacc tgcaagagtt cagctatagc aacctggagg agaaaaaaga agagccagcc     2700

acacctgctt acacaataag tgccactgag ctgctagaaa agcaggccac accaagagag     2760

cctgagctgc tgtatcaaaa tattgctgag cgagtcaagg aacttcccag cgcaggccta     2820

gtccactata acttttgtac cttacctaaa aggcagtttg ccccttccta tgaatctcga     2880

cgccaaaacc aagacagaat caataaaacc gttttatatg gaactcccag gaaatgcttt     2940

gtggggcagt caaaacccaa ccacccttta ctgcaagcta agccgcaatc agaaccggac     3000

tacctcgaag ttctggaaaa acaaactgca atcagtcagc tgtgaaggga aatcatttac     3060

aaccctaagg catcagagga tgctgctccg aactgttgga aacaaggaca ttagcttttg     3120

tgtttgtttt tgttctccct ttcccagtgt taatggggga ctttgaaaat gtttgggaga     3180

taggatgaag tcatgatttt gcttttgcaa gttttccttt aaattatttc tctctcgctc     3240

tcctcccctc cttttttttt tttttttttt tttctttttc ccttctcttc ttaggaacca     3300

tcagtggaca tgaatgtttc tacaatgcat ttcttcatag attttgttta tggttttgtt     3360

tcttttttct tctttgtttt tcagtgtggg agtgggaaga ggagattata gtgactgaag     3420

aaagaatagg caaacttttc aaatgaaaat ggatatttag tgtattttgt agaagatctc     3480

caaagatctt ttgtgactac aacttctttt gtaaataatg atatatggta tttccatcgt     3540

cagttaccga gtatagccac tgggtatcac tactttgtgt taaagtgcct tcgcacttta     3600

agtacattac ttaaatgttg cttttagctt tgataaattg aaaatatttt aatgtgttgt     3660

atttttgaaa ttgaaaacac tgtaaaatag attgatgtgt cagctatatt aagtcaacgt     3720

acagtttgct tgagttatag aaaccagcct gtcatcaaat gattctagtt ctaggacttt     3780

gtaggcttaa ctataaaata tttcctttcc tctgggttta agtgatttta tttaagtcaa     3840

ctaaggggat ttaacagtgg actagaggta ataagccacc tcagtcagga ttaataattc     3900

attaataaaa tatatttaac ccaaaaaaaa aaaa                                 3934


<210>  2143
<211>  910
<212>  DNA
<213>  homo sapiens

<400>  2143
ccagcgtcag gccagccccg gcatgctctg cggccgcccg cggtccagct ccgacaacag       60

gaattttctc cgagagcggg ccgggctcag ttcagctgct gtccagaccc ggatcggcaa      120

cagtgccgcc tccagacgtt ctcctgccgc tcgcccgccc gtcccagcgc ccccagccct      180

cccgcgaggg cgccccggga cggaaggatc caccagtctg tcggcgcccg ccgttctcgt      240

ggtcgccgtc gccgtcgtcg tggtggtagt ctccgccgtc gcctgggcca tggccaatta      300

catccacgtc cctcccggct ccccggaggt gcccaagctg aacgtcaccg ttcaggatca      360

ggaggagcat cgctgccggg agggggccct gagcctcctg caacacctgc ggcctcactg      420

ggacccccag gaggtgaccc tgcagctctt cacagatgga atcacaaata aacttattgg      480

ctgttacgtg ggaaacacca tggaggatgt agtcctggtg agaatttatg gcaataagac      540

tgagttatta gtcgatcgag atgaggaagt aaagagtttt cgagtgttgc aggctcatgg      600

gtgtgcacca caactctact gtaccttcaa taatggacta tgctatgaat ttatacaagg      660

agaagcactg gatccaaagc atgtctgcaa cccagccatt ttcagtttat catcgttgac      720

tctttgcaaa ggaaaaacta caagatgttt tggattaacc ggctgcagag ggtcaaggct      780

tctgcttagt tttttctagt tagtgtttga gttgaagtgt tatacatttc ttactgccga      840

ttgcttatta cttaattgtt catgttttca gagttcttgc ctattaaaat tttattaatt      900

tggttaacaa                                                             910


<210>  2144
<211>  7101
<212>  DNA
<213>  homo sapiens

<400>  2144
ccagcgtcag gccagccccg gcatgctctg cggccgcccg cggtccagct ccgacaacag       60

gaattttctc cgagagcggg ccgggctcag ttcagctgct gtccagaccc ggatcggcaa      120

cagtgccgcc tccagacgtt ctcctgccgc tcgcccgccc gtcccagcgc ccccagccct      180

cccgcgaggg cgccccggga cggaaggatc caccagtctg tcggcgcccg ccgttctcgt      240

ggtcgccgtc gccgtcgtcg tggtggtagt ctccgccgtc gcctgggcca tggccaatta      300

catccacgtc cctcccggct ccccggaggt gcccaagctg aacgtcaccg ttcaggatca      360

ggaggagcat cgctgccggg agggggccct gagcctcctg caacacctgc ggcctcactg      420

ggacccccag gaggtgaccc tgcagctctt cacagatgga atcacaaata aacttattgg      480

ctgttacgtg ggaaacacca tggaggatgt agtcctggtg agaatttatg gcaataagac      540

tgagttatta gtcgatcgag atgaggaagt aaagagtttt cgagtgttgc aggctcatgg      600

gtgtgcacca caactctact gtaccttcaa taatggacta tgctatgaat ttatacaagg      660

agaagcactg gatccaaagc atgtctgcaa cccagccatt ttcaggctaa tagctcgtca      720

gcttgctaaa atccatgcta ttcatgcaca caatggctgg atccccaaat ctaatctttg      780

gctaaagatg ggaaagtatt tctctctcat tcccacagga tttgcagatg aagacattaa      840

taaaaggttc ctaagtgata tcccaagctc tcagattctc caggaagaga tgacttggat      900

gaaggagatt ctttccaacc tgggctcacc tgttgtgctt tgccataatg acctattgtg      960

taagaatata atctacaatg agaaacaagg tgatgtacag ttcattgatt atgaatattc     1020

tggatacaac tacctggcat atgatattgg aaatcatttc aatgaatttg caggtgtgag     1080

tgatgtagac tatagtctgt atccagatag agaactacag agtcagtggc tgcgtgctta     1140

ccttgaagcc tacaaagaat ttaagggctt tgggactgaa gttactgaaa aggaggtaga     1200

aatactcttc attcaagtca atcagtttgc attggcttct catttctttt ggggattgtg     1260

ggctttgatt caagccaaat actccactat tgagtttgat ttccttgggt atgcaattgt     1320

tcgttttaac cagtacttta aaatgaagcc tgaggttact gcattaaaag tgcctgagta     1380

aagaagagat ttaattattc tccagtagct gagcaatgct tgtgaatctt ttcttaagaa     1440

atcccaaaaa gccaatatta gttaaaattc tgttgtttaa tttggttatc ttgctttata     1500

aattatgcct ctaaacaatc aaatctattt ttgaaataga ctgaatgatg tcaagaaata     1560

tacctactgc tatccgtatg tggtggatta gaaatgtgtt aaatctgcaa aaggtataaa     1620

gatgtcagtt taatttcttt gataatttaa cctatgttgt atgtgaatta tttattataa     1680

acttagcacg attctgtgac tgtttttctc tgtttcacgt tcgttgagtg taagcaatga     1740

aaatgtccca aataagtttt ttaagtttta ctttaataag attaatttca gtaaacattc     1800

tagttgttca gtgtaacctt tttatcttga tgcattgtaa gtaaaatgaa tcatttactc     1860

ttgaaatgcc agtcattgac tgatgtagat aatttaggat tttcatataa aaatagctgt     1920

ttaggaaggt gaaatacatt cactgtctct gttggtggta catcttgttg aattcaatat     1980

tagaaagtat ttctttttgg ggtaatataa cttagaatta aatccctgtt tctctatgta     2040

gtctggcagt ataaatataa atatttacca tataatcttg gaataagtat tagttaatgt     2100

taccaaaatc tgtattaaat aatgttttca aatgctaaat atggtcgtta ctattttcag     2160

ttttaaaaat tttatagtat caaattgttt ctaaccaaaa atttcctttt acttctagag     2220

atgctttatg tttttgatta ttaaatagtc actagtattg ctaatttttg aaacaaatac     2280

acaaaattta tcatatgtag aaataagaaa atattgttta ggttaattat tttttaccta     2340

tccagagtca ttccttacat ttcagtttca tgtttcattc ctcacatttt agtttcatgt     2400

tttagtttga ttctatgttt ttagactgat agcaaatgat tacttgatac atgtaagttc     2460

agcgttatat gttgaggcag ttatataatt aaataaggaa cacttagggc attgatcttg     2520

tacacttaaa atctgacaaa tgacaaaatg tgaattaagc ataaatagtc atggcaggag     2580

ggcttttgtt tatttctctt gtttttgttt aactgtattt ttaattttgt ctggtggtaa     2640

gagggaggta attattgtat ggaaagaagt tagatctttc agatagataa ataggcttca     2700

ggttttgaag tctgctctgt gtagttgagc agtcatggtt aactttactt agaaaattag     2760

tctgacaagc tttgcacttc ggtcacataa gtgcccatgt acaaagttgg cttactggat     2820

ctgcatattc aaaatatgca actacaaatt tatcctctga gaaatcttct gaggagtcta     2880

atgtattcca aatgacttaa tattctcaga caaatgcttt aaaatacttg gattatctca     2940

agatttttga agctaataaa gtaaatagaa acacaggcca ttttaaatgg taaattctag     3000

ttacataaat ataatcttaa agtatgtttg tatctgtaac agtgttagac cagatttggt     3060

ttctacctcc ccaatgttat aaatgttcac ttttgttttt ataaaccata ttactgtaag     3120

atcaatagaa ctttgcctag ttaagtgaat ggaaccaatt aaacaactag tagcttttta     3180

taatgttagt gtgaacttga aaaattgttt ttggtggaat ttttgtctgt ggttagaaca     3240

ttttcataaa acagataaag aatgtgtaat actcttaatt tttttttttt tttttttttt     3300

ttttttgctt tctgccttct aaagtgcaac agtatatatc ttgtagaact gtgggaggag     3360

agaagataat ttttctacct tactccatat tcttacttca aactattttg aatagaggtt     3420

cactgagcca ttgctgatag actgtgcata gctactagct gtcacactat tgtaggtttt     3480

ttggagagat tcatagggaa gtgaatgtaa ccaggaataa aggctctcac tttagctctg     3540

ggactatgca gtggatcttg ggaacaaaat aagatatcta atctattttc cccattctgg     3600

ctagattttg gttgttgtga tgctcctact tcctgtatag gtttttggga tcatggtgca     3660

ggctagtaat aggattcaga attgcttccc ttttatatcg accatgtaag ggattctaaa     3720

ggagggtaaa tctcaaagtg ctctgaaatc atccctctaa aatctgtcct gtggtgtgct     3780

aagatgtctg ttgccttttt atgttaagct aaggaacttg aatgccttac ctaataactc     3840

aactagtagt aagctcattt tgtaaatatg aaaatggctg taagaagtgg cattcatgta     3900

tattcaatgt tagtcaatag accatagtgg cctggatgct ttaacaagcc aaattccgca     3960

attttttttc cttttttccc cttcatactt gtatgatctc acctgaccag tgatttcttt     4020

tcctcctaac cccatgctac caccattttc tggaaatcaa agagatgtgg tagtaaatca     4080

tacagtacac acgatcatct gagatcaata tgagcacaaa actcatcaag taggtctgcc     4140

tggaatgtat ataaaaaatg taaataaaaa tttgtaaatt agtgtgaact gtatcttgca     4200

tatgagactg tgtattgttt tgcattctct tcccttttgt agaaattttt ctgtaaggaa     4260

atgattcagc ttgttggttt tagagtaaaa atagccaaca gttgtggcta cacagtgaga     4320

tcacaggaac tggaaatagg gtttgtcggc tttggttaat gtcagtactc atttatttag     4380

cctctcagtg cttaataaga cttttcttta ttttttagtt agccgttagg ttttgtgagg     4440

ttagattcct ggaagcagtg aatttataca ctgttatatt aatagagctc cgttctttga     4500

gtcatgattc caagctaaag gaaattaaaa atgtaattta ataatttcct atttttaggg     4560

ttgttaattt ttttctacaa aaaaaccttg aaattttaga tatcccaatg tgaatctaat     4620

ttccatatat acagaaatta gacaaataat aagtctttag ttcaacttaa gcatatctca     4680

aatgacttct ctaaatttaa agttgatcat gataggatca taaaagacag aaaagactta     4740

agtaatcttg taatgacaat tatttccatt tttgctgaac taaaaatatt taacttcata     4800

aatatgttac tacagcttcc agatttaaag aaaaaaagtt tcccccactc tcaattaaaa     4860

gttagaaccc tccactttta aaattataca aatatttctt ttttacatta cacagaagcc     4920

ttctgtacca ttttacgaat ttctgtcttc ataatataag tgaaaatact gtcatttcaa     4980

ttttctgctt taaattgttt ttaataagca ttccaaagtg atacagactt aagcttttaa     5040

tcaatcagtc attcagttga tagacaaagt tagcgatgct ttatgctagg aaacttgttg     5100

acagtaacct gtgcgacttt atgcagaaga caaatgctag taattattat gcacagagga     5160

aaaatcattt taagtatgtg gtaaagcagc ttcatctttc aaaattgatt tgctctggtt     5220

tttctttagt ccattagatt ccagaatgtc cttttactgg gaatttagtt atgtattaag     5280

ataacctgtt ttcagttctt tttgaaaaga agacattatt tatattgaac caccttattt     5340

taaaattttt aacttttata taccacttgt gtgattccag tgtcatgtct tgggtttgat     5400

gtcgttggac agaaaagtgt atcaattatt ttaaatgaat ttttccccat gtttgaggct     5460

tagtctgtaa atgtgttgct gtaacagaaa atacttgggt atgcattact tgaatacttg     5520

aaaactgaaa ttaataagat gtattacata atgaattaga tttctctgaa cagtttttac     5580

actgaaaatc ttcatttctg gattgcagtt tgaaatggaa tgaagacctg aattatttgg     5640

gtagaaaaaa ttatgatagt gcttataaga actgtaaact gttttaaact attttgtgtt     5700

tgacgcatca aacttcaagt tttttgtaag tttctctcct gaaattttct ttctcttcta     5760

tactttatgc acttactata ctactgatgt aataaaagag cagggttaaa aatattgtat     5820

ctgtattcat tgtgaatcct gtagcttttc tagttaacaa aaaatcgctt tctaaaatac     5880

tcttaatccc attgttttgg ttaacatctt acccatttgt tgtatttcaa atgccattaa     5940

tcattttagt acaacaccta tgtttataaa aatttgaaaa cattacatat tgtatttaaa     6000

actaattagt gaagagtaag aaaaaaacta gccaacagaa ttgtaggtga tgcattagtt     6060

aaatttcaaa actcataata aaggaacttt cagagattgg ttgaaaccca gtggtatccc     6120

tgtaaattag ctcctgtgac tggaaaagac cccaaaaagg cagtagagga gattagtgtt     6180

tacttgctgt ggttgtggtg tgctgctact taattatagg tagtgacaca ctgaaattct     6240

tatttgtcca ataatctgaa gtagtttcct atatttatct gtactaaatt gactataaat     6300

tgagtctgca aagaggaaac tttttgactg tactgtattt aggagccttt gtacagcttg     6360

gtcaaatttc catgatatga agtatttgag ttttaaaata tactgttatt aaaaggaaaa     6420

agacatggcc attattccat gtgcttaaat gataatttcc ttattcagtt tcagaagaaa     6480

aagaatgaaa ttgggtaact gtcattgcgt tagctttatg ttgaattggg aaattgtggc     6540

ataaagctta aattcgtgtt tatcaaatgt gaaccatagt agtataatgc tgctttgtat     6600

ataatgtaag tgctacaaat agtctcagca ctgaaaatgt attgatacct cttaaatgaa     6660

tgcaactttt gatgtaggtg ttttgctatg cctcagaaaa tatctgtctg agaatttgtt     6720

aatctgtttg ataatgaaga tacttcctgt tttcttgttt catattttca tgttcaaaat     6780

ttaagtttta catttttact actgttaatt taaataaaat ttgttctgtg gataaaatga     6840

ggttggcagt gaagaaaatt aaaaacagcc tcattcatgt aactggttaa gtaaaaatac     6900

attttcacta tgtgttcata aacttttaat gaagctgttt gtctttcagt tcaaatataa     6960

gtgatgttta ggctttattt ctgttaataa ggctttttac cattgattaa atgaaggaat     7020

gtatcttttt gaagagattt atattctgta aataaaaatt cgttgtaaca ataaagttga     7080

gttctaacta cagtgtattc a                                               7101


<210>  2145
<211>  3784
<212>  DNA
<213>  homo sapiens

<400>  2145
cgtttcctcc cctcccctcc actcggccgt ccctccttcc tcctccctcc tccctcctcc       60

tcccgctcct gaagagcgcg ccgcgtgggg gacggcccgg ttacttcctc cagagactga      120

cgagtgcggt gtcgctccag ctcagagctc ccggagccgc ccggccagcg tccggcctcc      180

ctgatcgtct ctggccggcg ccctcgccct cgcccggcgc gcaccgagca gccgcgggcg      240

ccgagcagcc accgtcccga ccaagcgccg gccctgcccg cagcggcagg atgaatgatt      300

tcggaatcaa gaatatggac caggtagccc ctgtggctaa cagttacaga gggacactca      360

agcgccagcc agcctttgac acctttgatg ggtccctgtt tgctgttttt ccttctctaa      420

atgaagagca aacactgcaa gaagtgccaa caggcttgga ttccatttct catgactccg      480

ccaactgtga attgcctttg ttaaccccgt gcagcaaggc tgtgatgagt caagccttaa      540

aagctacctt cagtggcttc aaaaaggaac agcggcgcct gggcattcca aagaacccct      600

ggctgtggag tgagcaacag gtatgccagt ggcttctctg ggccaccaat gagttcagtc      660

tggtgaacgt gaatctgcag aggttcggca tgaatggcca gatgctgtgt aaccttggca      720

aggaacgctt tctggagctg gcacctgact ttgtgggtga cattctctgg gaacatctgg      780

agcaaatgat caaagaaaac caagaaaaga cagaagatca atatgaagaa aattcacacc      840

tcacctccgt tcctcattgg attaacagca atacattagg ttttggcaca gagcaggcgc      900

cctatggaat gcagacacag aattacccca aaggcggcct cctggacagc atgtgtccgg      960

cctccacacc cagcgtactc agctctgagc aggagtttca gatgttcccc aagtctcggc     1020

tcagctccgt cagcgtcacc tactgctctg tcagtcagga cttcccaggc agcaacttga     1080

atttgctcac caacaattct gggactccca aagaccacga ctcccctgag aacggtgcgg     1140

acagcttcga gagctcagac tccctcctcc agtcctggaa cagccagtcg tccttgctgg     1200

atgtgcaacg ggttccttcc ttcgagagct tcgaagatga ctgcagccag tctctctgcc     1260

tcaataagcc aaccatgtct ttcaaggatt acatccaaga gaggagtgac ccagtggagc     1320

aaggcaaacc agttatacct gcagctgtgc tggccggctt cacaggaagt ggacctattc     1380

agctgtggca gtttctcctg gagctgctat cagacaaatc ctgccagtca ttcatcagct     1440

ggactggaga cggatgggag tttaagctcg ccgaccccga tgaggtggcc cgccggtggg     1500

gaaagaggaa aaataagccc aagatgaact acgagaagct gagccggggc ttacgctact     1560

attacgacaa gaacatcatc cacaagacgt cggggaagcg ctacgtgtac cgcttcgtgt     1620

gcgacctcca gaacttgctg gggttcacgc ccgaggaact gcacgccatc ctgggcgtcc     1680

agcccgacac ggaggactga ggtcgccggg accaccctga gccggcccca ggctcgtgga     1740

ctgagtggga agcccatcct gaccagctgc tccgaggacc caggaaaggc aggattgaaa     1800

atgtccagga aagtggccaa gaagcagtgg ccttattgca tcccaaacca cgcctcttga     1860

ccaggctgcc tcccttgtgg cagcaacggc acagctaatt ctactcacag tgcttttaag     1920

tgaaaatggt cgagaaagag gcaccaggaa gccgtcctgg cgcctggcag tccgtgggac     1980

gggatggttc tggctgtttg agattctcaa aggagcgagc atgtcgtgga cacacacaga     2040

ctatttttag attttctttt gccttttgca accaggaaca gcaaatgcaa aaactctttg     2100

agagggtagg agggtgggaa ggaaacaacc atgtcatttc agaagttagt ttgtatatat     2160

tattataatc ttataattgt tctcagaatc ccttaacagt tgtatttaac agaaattgta     2220

tattgtaatt taaaataatt atataactgt atttgaaata agaattcaga catctgaggt     2280

tttatttcat ttttcaatag cacatatgga attttgcaaa gatttaatct gccaagggcc     2340

gactaagaga agttgtaaag tatgtattat ttacatttaa tagacttaca gggataaggc     2400

ctgtgggggg taatccctgc tttttgtgtt tttttgtttg tttgtttgtt tgtttttggg     2460

gggttttctt gccttggttg tctggcaagg actttgtaca tttgggagtt tttatgagaa     2520

acttaaatgt tattatctgg gcttatatct ggcctctgct ttctccttta attgtaaagt     2580

aaaagctata aagcagtatt tttcttgaca aatggcatat gttttccact tctttgcatg     2640

cgtttaagtc agtttataca caaaatggat tttatttttt agtttaactg tgtttctccg     2700

acagctcacc tctctctgac cacccagcca tttccttcct gtgctccacg ttcttctgtg     2760

tgattaaaat aagaatatta tttttggaaa tatgcaactc cttttcagag atcaggaggg     2820

atttatgtag cagctatttt tactgcaaaa gtaattcact ggaaaaaaaa tgtaatttgt     2880

aagaaagctt tatttttatc tcagctctat gtaaagttaa agttactgta cagagctgaa     2940

ggacgggggg cggtaggggt cttgatgaaa cctcttgaac gaagcacagt ttgtcccatc     3000

tttgttcact cgtgtgtctc aaccatctta atagcatgct gctccttttt gctcagtgtc     3060

cacagcaaga tgacgtgatt cttattttct tggacacaga ctattctgag gcacagagcg     3120

gggacttaag atgggaaaga gaaagcatcg gagccattca ttcggagaaa acgttttgat     3180

caaaatggag acttttgtag tcgtttcaaa agagcacctg agtcatgtgt attcccggcc     3240

tttataaatg acccggtcaa gttggtttca aagtccgaca ggcttgtctg tttactagct     3300

gcgtggcctt ggacgggtgg ctgacatctg taaagaatcc tcctgtgatg aaactgagga     3360

atcgggtggc cgggcaagct gggaagagca aagccagagc tgcgctgcct caatacccac     3420

aaaagaccat tcccagtata cataagcaca ggatgttttt ctcaagaggg atgtatttat     3480

cacttggaca tctgtttata atataaacag acatgtgact gggaacatct tgctgccaaa     3540

agaatcctag gcagtggctc attgtatgtg aggttgaacc acgtgaaatt gccaatatta     3600

ggctggcttt tatctacaaa gaaggagttt catggggttc agcctaacag ttatggaaac     3660

tacagtcctt ataaaccatt ggcatggtaa taaacagatc ttaagtataa aaattttgta     3720

attgggcctt tactctctca ataataaagt attttgttta tataaaaaaa aaaaaaaaaa     3780

aaaa                                                                  3784


<210>  2146
<211>  4494
<212>  DNA
<213>  homo sapiens

<400>  2146
gcgaccctcc gcccgccctc ggaagaccga gacagcggag aggttgcggg tgagctgcgc       60

tgagcccagg agccgaggag tcgggagcgc agtagcgctg agcccgagcc cgagcggccc      120

cgcgtcccga gcgcatcgga gcggccgagc cgcccggatg cagcgcctgt cccgggcagc      180

gcagccccgg ccgcaggatc tcacccaggg tggcagaagg aggccttctg gagctgaccc      240

acccccgacg accatcaggg tgaggcaact ccaaggtcct actctctttc tgtgcctgtt      300

acccaccccg tcctcctagg gtgcccttga gccgcaaaac tgctgtccac gtggaccggg      360

ggtgacatcg cacgtccatc tgccaggacc cctgcgtcca aattccgaga catggcgacc      420

aacggcagca aggtggccga cgggcagatc tccaccgagg tcagcgaggc ccctgtggcc      480

aatgacaagc ccaaaacctt ggtggtcaag gtgcagaaga aggcggcaga cctccccgac      540

cgggacacgt ggaagggccg cttcgacttc ctcatgtcct gtgtgggcta tgccatcggc      600

ctgggcaacg tctggaggtt cccctatctc tgcgggaaaa atggtggggg agccttcctg      660

atcccctatt tcctgacact catctttgcg ggggtcccac tcttcctgct ggagtgctcc      720

ctgggccagt acacctccat cggggggcta ggggtatgga agctggctcc tatgttcaag      780

ggcgtgggcc ttgcggctgc tgtgctatca ttctggctga acatctacta catcgtcatc      840

atctcctggg ccatttacta cctgtacaac tccttcacca cgacactgcc gtggaaacag      900

tgcgacaacc cctggaacac agaccgctgc ttctccaact acagcatggt caacactacc      960

aacatgacca gcgctgtggt ggagttctgg gagcgcaaca tgcatcagat gacggacggg     1020

ctggataagc caggtcagat ccgctggcca ctggccatca cgctggccat cgcctggatc     1080

cttgtgtatt tctgtatctg gaagggtgtt ggctggactg gaaaggtggt ctacttttca     1140

gccacatacc cctacatcat gctgatcatc ctgttcttcc gtggagtgac gctgcccggg     1200

gccaaggagg gcatcctctt ctacatcaca cccaacttcc gcaagctgtc tgactccgag     1260

gtgtggctgg atgcggcaac ccagatcttc ttctcatacg ggctgggcct ggggtccctg     1320

atcgctctcg ggagctacaa ctctttccac aacaatgtct acagggactc catcatcgtc     1380

tgctgcatca attcgtgcac cagcatgttc gcaggattcg tcatcttctc catcgtgggc     1440

ttcatggccc atgtcaccaa gaggtccatt gctgatgtgg cggcctcagg ccccgggctg     1500

gcgttcctgg catacccaga ggcggtgacc cagctgccta tctccccact ctgggccatc     1560

ctcttcttct ccatgctgtt gatgctgggc attgacagcc agttctgcac tgtggagggc     1620

ttcatcacag ccctggtgga tgagtacccc aggctcctcc gcaaccgcag agagctcttc     1680

attgctgctg tctgcatcat ctcctacctg atcggtctct ctaacatcac tcaggggggt     1740

atttatgtct tcaaactctt tgactactac tctgccagtg gcatgagcct gctgttcctc     1800

gtgttctttg aatgtgtctc tatttcctgg ttttacggtg tcaaccgatt ctatgacaat     1860

atccaagaga tggttggatc caggccctgc atctggtgga aactctgctg gtctttcttc     1920

acaccaatca ttgtggcggg cgtgttcatt ttcagtgctg tgcagatgac gccactcacc     1980

atgggaaact atgttttccc caagtggggc cagggtgtgg gctggctgat ggctctgtct     2040

tccatggtcc tcatccccgg gtacatggcc tacatgttcc tcaccttaaa gggctccctg     2100

aagcagcgca tccaagtcat ggtccagccc agcgaagaca tcgttcgccc agagaatggt     2160

cctgagcagc cccaggcggg cagctccacc agcaaggagg cctacatcta gggtgggggc     2220

cactcaccga cccgacactc tcaccccccg acctggctga gtgcgaccac cacttgatgt     2280

ctgaggatac cttccatctc aacctacctc gagtggcgag tccagacacc atcaccacgc     2340

agagagggga ggtgggagga cagttagacc cctgggtggg ccctgccgtg ggcaaggata     2400

cccggtggct tctggcacct ggcgggctgg tgaccttttt aatccaggcc ccatcagcat     2460

cccacgatcg gccttggtaa ccgccgcggt agatcatttt tatcccgcca gggagtgtga     2520

tgcaggaaga ccacatgcgc tcctggcttt taaacctgtt cctgactgtt ctcttactgc     2580

cgaaaccctt gactgttatc tcggactttg caggagttcc tttccctccg aacgctgctc     2640

catgcacagg aaaagggcat tttgtacaat ggggacttcc cgggaacgct tgctcttaag     2700

taccagaagc cggcggagct ctggctttcg tgtttttggt tttctccttc ccaaggcagc     2760

tggattgaaa aaacaaaaca aaacaaaaaa acccaggggc gtcagtcgat attcccaggg     2820

ccgcttctcc tgcagtctgt ggagcgtcct tgtccccgcc gccggaatga atgagcattc     2880

tgcagcccga tgtccctgtc ccctcctcgc cgggccattc tgattggacc tggcccagtg     2940

caatctgtcc agacaagccc tgcttgctgg aaaactgcca caagcacaat tgatctcttt     3000

ttatcgccat tccaggggcc tcaggtccta ctggggaaac ttcctatacc ggagctccag     3060

tttctcttaa gctgcccaat ttcacagagt acaaaatagt tgtaggggaa atcaaggtga     3120

aggatctgtc cgacagtcaa gacggatcca cagtaatctt tcggtctcct taaactacca     3180

ccctcgctgc cacccacccc aagctgctgc cgcctcacct tccttgaaat ttctcagcgg     3240

gagtctcctc actgccacta aaatccaccc agcccactaa ctgaggagct agtgttaatc     3300

cagagaaccc cccgcaatgt gcttccgaga ttcagactgc ttcattggga agtatgattt     3360

gttcctttct ggaattgggc tccgtggtgg cggcggcact tcaagcaaag acagtttctt     3420

gcaagctcca gtagctccgc gtgtctcatt tgccaggaag atgggttccc acgtagcaaa     3480

tcgtacattg tgccctgtag ctccttagct agttagctca caagccgtgt tttatgacta     3540

atccttaata actatggtaa ataactgtga ctgtggggtt tttaatctct tgtcattctc     3600

atccaaaagt gaccagcata ccagttcttg caataagata ttaccctcag aatattaagc     3660

acattattgt agagaaaaaa aaatatgtgt acacatatga acgcacaaca tgcacattca     3720

tcctcacatg tggcacgtaa ggtctcattt gatattgtgt aggaaatctg aagccttttc     3780

ctgaggtcat ctgtaaaata gtctcattgc caaggcatcc ccagtgccag ctggtgaatc     3840

catgatcaaa atgcatacgt attgttaaat gataaggttt agaatgacag gaacccatca     3900

ctgtgtctca tggtcccact tccccatctg tgtgtgaatt cctttagact aagggcagga     3960

agacttccag ctttctcttt gttcttcaat gtgaaactga gaccaagtct ctctaagaca     4020

aatgcagtgt atttaatgtt tgtaagcaat tctaagtgag atgtttggca agaaatcccc     4080

taactgattt ccatccaaac ctaccttata gagcacaata ttaagtgttg tacaattact     4140

gtgagaactg tgaatatgtg taactttttt ttagtatttg cccgggggga aaaagatatt     4200

gtattatcat atatgctttt ttgcaataag gatttattct cagaacacca agtaaatcta     4260

tctctatata aaaaatatat gtaatatata catattcaaa gtatatacag agcctgtttt     4320

aaaaaataca gtattattta gtaaaattat ctgttctatg gaccaaatgt aaaatattta     4380

taaatgaaga tgcattttaa atgtctataa atggtgtcat aactagagca cgggcgttat     4440

gtaagtttct aagaatttag aggataaata ataaaggttc tatgatatac aaca           4494


<210>  2147
<211>  1587
<212>  DNA
<213>  homo sapiens

<400>  2147
gcggcggttt tttttcccat ggcgctctgg ggcgcgggcg atttgtaggt aatggcaggc       60

gttcggtcac tgaggtgtag cagaggatgc gctggcggct gtgagtgcgg cgacaagggc      120

aaatgcagcg actcctcgct gttgggcaag agactctccg aagactcgag ccgccaccag      180

ctgttgcaga agtgggcgag catgtggagc tccatgagcg aagacgcgtc ggtggccgac      240

atggagaggg cgcagctgga ggaggaggcg gcggctgcgg aggagaggcc gctggtgttc      300

ctgtgctccg gctgccggcg gccgctgggc gactcgctga gctgggtggc cagccaggag      360

gacaccaact gcatcctgct tcgctgtgtt tcctgtaatg tttctgtgga taaggaacag      420

aagctatcca aacgtgaaaa ggaaaatggt tgcgtccttg agactttgtg ctgcgcgggg      480

tgctcactca atcttggcta cgtgtacaga tgcacgccca agaatcttga ttacaagaga      540

gacttgtttt gcctcagtgt tgaagccatt gaaagttatg ttttagggtc ctctgaaaag      600

caaattgtgt cagaagataa agagcttttt aatcttgaaa gcagagttga aatagaaaag      660

tctctaacac agatggaaga tgtcttgaaa gcattacaaa tgaagctgtg ggaggccgaa      720

tccaaattgt cctttgccac ttgtaaaagc tgaactctag tctgtgtcct ccattctgcc      780

cccgcccttc ctccccttat ttgttaaatg aagcaacata gtgagacgtc gtctctacaa      840

aaaaaaaaag aaaaaaaaaa ttagccaggc atgcgaaacg ctgaggtggg aggatcagat      900

gagcttggga ggttgaggct gcagtgagcc ttggtcatgc cactactgtg ttctagtctg      960

ggcaacagag tgagaccttc tctcaaaaaa aaaacccaaa attgtagaat tacttctata     1020

gctatatttt atgataaaga agtgattgtt tctcaaaatc gcattttaaa gacgttttat     1080

ggtacttgtt ggaattggga cttaggagtt ttgattttga taagaaactg ggataatttt     1140

ctgaactttt tttcctctgt atcacattta tttactattt ttaaaaactt tgacatttaa     1200

cacttgggac aacatttatt ataaatgata agaaaaatct tagaggtttg tctacccaca     1260

gtgtcatgga atcttctctg aaaactaatc cataaagttc cctggagaaa ttggtcagaa     1320

tgatctgtca gaaccatttg aaaacttgct caagagcagt tgcttatata tagtaggatt     1380

ttactttttc ctgcttatgt actactatat gcttaaaaaa cctggaggaa tacttaccaa     1440

agaggagtaa ccatctctga gggtgggatt ctgggggaat ttttgttttt ttctgttttc     1500

tataatgtga aacttttgta gtatgtattt ttctaattga agagaataaa gattaaaaca     1560

aagtgcttta aaaaaaaaaa aaaaaaa                                         1587


<210>  2148
<211>  3419
<212>  DNA
<213>  homo sapiens

<400>  2148
gcacgcacgc acgcacgcca gcggccggcg gggccgcagg ctcgcgcccg ggctcgcccc       60

gcgccgctcc agaggctcgc gcactcagca ggttgggctg cggcggcggc ggcagctgtg      120

gaagctcagg cgctgcgcgt gagaggtccc agatacgtct gcggttccgg ctccgccacc      180

ctcagcttct cttccccagg tctgggagcc gagtgcggaa ggagggaacg gccctagctt      240

tgggaagcca gaggacaccc ctggctcctg ccgacaccgc cctccttccc ttcccagccg      300

cgggcctcgc tcggtgctag gctactctgc cgggaggcgg cggcggctgc cagtctgtgg      360

agagtcctgc tgccctccag ccgggctcct ccaccgggcc ttgcaggggc cgagagagct      420

cggtgcccgc ccttccgctc gcctttttcg tcagctggct ggagcagcat cggtccggga      480

ggtctctagg ctgaggcggc ggccgctcct ctagttccac aatgtccacg ggcggagact      540

tcgggaatcc gctgaggaaa ttcaagctgg tgttcctggg ggagcaaagc gttggaaaga      600

catctttgat caccagattc atgtatgaca gttttgacaa cacctatcag gcaacaattg      660

gcattgactt tttatcaaaa actatgtact tggaggatcg aacaatcagg cttcagctgt      720

gggatactgc gggtcaggaa cgtttccgta gcctcattcc cagttacatc cgtgattctg      780

ctgcagctgt agtagtttac gatatcacaa atgttaactc attccagcaa actacaaagt      840

ggattgatga tgtcagaaca gaaagaggaa gtgatgttat catcatgcta gtaggaaata      900

aaacagatct tgctgacaag aggcaagtgt caattgagga gggagagagg aaagccaaag      960

agctgaatgt tatgtttatt gaaactagtg caaaagctgg atacaatgta aagcagctct     1020

ttcgacgtgt agcagcagct ttgccgggaa tggaaagcac acaggacaga agcagagaag     1080

atatgattga cataaaactg gaaaagcctc aggagcaacc agtcagtgaa ggaggctgtt     1140

cctgctaatc tcccatgtca tcttcaacct tcttcagaag ctcactgctt tggccccctt     1200

actctttcat tgactgcagt gtgaatattg gcttgaacct tttcccttca gtaataacgt     1260

attgcaattc atcattgctg cctgtctcgt ggagatgatc tattagcttc acaagcacaa     1320

caaaagtcag tgtcttcatt atttatattt tacaaaaagc caaaatattt cagcatattc     1380

cagtgataac tttaaaaatt agatacattt tcttaacatt tttttctttt ttaatgttat     1440

gataatgtac ttcaaaatga tggaaatctc aacagtatga gtatggcttg gttaacgagc     1500

ggtatgttca cagcctactt tatctctcct tgcttttctc acctctcact tacccccatt     1560

ccctattacc ctattcttac ctagcctccc ccgacttcct caaaacaaac aagagatggc     1620

aaagcagcag ttctaccaag cccattggaa ttatccttta attttacaga taccacttgc     1680

tgtaggctac ggaccaagat gtccaaaatt attcttgagc actgatataa attacggtct     1740

tctttgaggt caaaattcag ccatcatggt aggcagtgct tgaatgagaa aaggctcctg     1800

gtgcatcttc aaaatgagtc ctaaagaaca tactgagtac ttagaagtag aagaacataa     1860

gatgtatttc tgactaaaac aaatggctct ttcacatgtg ctttattaga ctctgggaga     1920

gaaaattaac caagtgcttc agaacaggtt tttagtattt aattcttcac ggtaagaaaa     1980

tgaagttcta atgaactgtt tctcccaagg ttttaaaatt gtcaagagtt attctgtttg     2040

tttaaaaaat aagaaacctc tttaagcaat agattttgct tgggttttct tttttaaaaa     2100

cataatactg tgcaggcaag gcactgtaaa agttttaatt ccttccagaa gaaccagtgg     2160

aagaatttaa atttggcgct acgatcaaaa ctactgaatt agtagaaata atgatgtcta     2220

aagcttacca acaaaagaac cctcagcaga ataacaaaaa ctttgctcag gacatttgag     2280

gtcaaattga agacggaaac cggaaaccgt tttcttgtaa gcccctagag gcagatcagg     2340

taaagcatac atagtagagg gaaaggagag aatggaaata aaactcaata ttatgcagat     2400

ttatgcctta ttttttagca ttttttaagg ttgggtcttt caggctggtt ttggtttgta     2460

ttagatctgt atagtttaat taactggtga tttagtttta tatttaagct acaattaatc     2520

ttttttcttt ggtgatattt atttctttgc cttttttttt tttaacaact ttcaatcttc     2580

agatgtttcg ttgaatctat ttagagcttc accatggcaa tatgtatttc ccttaaaaca     2640

ctgcaaacaa atatactagg agtgtgccct tttaatcttt actagttatt gtgagattgc     2700

tgtgtaagct aataaacaca tttgtaaata cattgtttgc aggacgaaaa cttctgagtt     2760

acagctcagg aaaagcctgc tgaatttatg ttgtaagcat tacttaacac agtataaaga     2820

tgaaaagaca acaaaaatat cttcatactt cctcatcccc tcattggaac aaaaccttaa     2880

actgggagaa ccttagtccc ctctctttcc tcttcctcct ccacttccca cttattgtca     2940

ccttgtaata ttcagagagc acttggatta tggatctgaa tagagaaatg cttacagata     3000

atcattagcc cacataccag taacttatac ttaaagatgg gatggagttg taaagtgctt     3060

ttataataca atataattgt taaaggcaag ggttgactct ttgttttatt ttgacatggc     3120

atgtcctgaa ataaatattg attcaatatg gcagatgggt catattcttt atttggaaga     3180

agttgtgact tctgacatgg gtgtgattgt cttcctacac tgttgcattt gattcttttt     3240

atgtattttt aagaaagtaa ccagttatac tgcttttaat attgattggt ctttttattt     3300

ggcttggagt tcttcaaagc attgaagtgt gttcatagtc caggtttttt ttttaataaa     3360

cacaattttg ctgccaaaaa tatataaata aaacacgaaa gaaaacaaaa aaaaaaaaa      3419


<210>  2149
<211>  1826
<212>  DNA
<213>  homo sapiens

<400>  2149
gcatgcccat agaggctggc ggggctggac gcgccgggcg gggacccgga ggaggggcgc       60

gcgctgtggc gtcgggtgtt ttggtttgga tttttttttc cgcgaaagaa gtttgctttg      120

gccacgcctc aaggcggccg cctcctcctg ccccctcctc cgcccctccg cgcacacctc      180

tcggtgcaga ttgcaaagcg ccttccgttg cgagagctgc agattttgca agagccaggc      240

tcgcccacct tgtagaagga gcgccttgag tcccctctca ccctcggttg caaagagccg      300

accgcttgat ctggacaccc cctcgcccag attgcatgat ctcccgggac cctcttgagt      360

tgcacgtttc tgcaccgagg acctcaaatc cccgtcgctc ctaggatttg cagcgttctg      420

gatactggag ggttgcaggc tacactcgcc cgcccctggg cagacactcg tccaaaccac      480

tggagtgtgc tggtgactgg caggccagcc cttcgcctct ccatgaaccc gtgagcctgg      540

gggcaggtgc caggcgatgg cgcggcctgt gagcgacagg accccggccc ctctgctgct      600

gggcggcccg gccgggacac cccctggcgg gggagcgctg cttgggttgc ggagccttct      660

gcaggggacc agcaagccca aagagccggc cagctgtctc ctgaaggaaa aggagcgcaa      720

ggcggccctg cctgcagcca caacccctgg gccaggcctg gagactgcgg gcccggcgga      780

tgccccggct ggggcagtgg tgggcggagg gtccccgcgg gggcgcccgg ggccggtgcc      840

cgccccgggt ctgttggcgc cactgctgtg ggagcgcacg ctgccgttcg gcgatgtgga      900

gtacgtagac ctggacgcct tcctgctgga gcacgggctc ccgcccagcc cgccgccccc      960

cggtggcccg tcgccggagc cgtcgcccgc gcggacgccc gcaccctccc cagggccggg     1020

ttcgtgcggc tcggcttccc cccgctcctc tcctgggcac gcccccgccc gggctgccct     1080

cgggaccgcc agcggccacc gcgcaggcct gacctctcgg gacacaccca gccctgtgga     1140

cccagacacc gtggaggtgt tgatgacctt tgaacccgac ccagctgatc ttgccctatc     1200

aagcattcct ggccacgaga cctttgaccc tcgaagacat cgcttctcag aagaggaact     1260

taagccccag ccaatcatga agaaggcaag aaaaatccag gtgccggagg agcagaagga     1320

tgagaaatac tggagccggc ggtacaagaa caacgaggca gccaagcggt cccgtgacgc     1380

ccggcggctc aaggagaacc agatatcggt gcgggcggcc ttcctggaga aggagaacgc     1440

cctgctgcgg caggaagttg tggccgtgcg ccaggagctg tcccactacc gcgccgtgct     1500

gtcccgatac caggcccagc acggggccct gtgaggctgc cccacatccc cacctggcgg     1560

agctctcctc cgccttgctg agacttacgc cctgttccct tcctgccctg tggcccacgg     1620

gccggccagc tgggtgcccc agggacgtga taatgcagat aaatacattt atatttttaa     1680

gaaaaagcga gcctcccccc tcccttgcgg gggcggggag ggttctctgt gtgtgtcccc     1740

ggcacgtcag ggaccctatc ctcccaccgc ctccgttaac acgatcctga ataaatcttg     1800

agaaccccag aaaaaaaaaa aaaaaa                                          1826


<210>  2150
<211>  3018
<212>  DNA
<213>  homo sapiens

<400>  2150
ggggaggggt gtgacgtaca tccggcgagt agctggcggt cccgggtgct gctggttagt       60

gtgctctgag ggagggtccg agccagccgc tgttttgccg gaggagcccc tcaggccgta      120

gtaagcatta ataatgtctt tcatctttga gtggatctac aatggcttca gcagtgtgct      180

ccagttccta ggactgtaca agaaatctgg aaaacttgta ttcttaggtt tggataatgc      240

aggcaaaacc actcttcttc acatgctcaa agatgacaga ttgggccaac atgttccaac      300

actacatccg acatcagaag agctaacaat tgctggaatg acctttacaa cttttgatct      360

tggtgggcac gagcaagcac gtcgcgtttg gaaaaattat ctcccagcaa ttaatgggat      420

tgtctttctg gtggactgtg cagatcattc tcgcctcgtg gaatccaaag ttgagcttaa      480

tgctttaatg actgatgaaa caatatccaa tgtgccaatc cttatcttgg gtaacaaaat      540

tgacagaaca gatgcaatca gtgaagaaaa actccgtgag atatttgggc tttatggaca      600

gaccacagga aaggggaatg tgaccctgaa ggagctgaat gctcgcccca tggaagtgtt      660

catgtgcagt gtgctcaaga ggcaaggtta cggcgagggt ttccgctggc tctcccagta      720

tattgactga tgtttggacg gtgaaaataa aagagtttta cttctctgga ctgatcctat      780

tcacagcttc ctcatgaact tttctaatag aacaaggaaa gctctccaac catgtctggc      840

gttgagaagc caagagtctc tgtcaactct ctcattgccc agtggtgaca tgtgctcttc      900

tccacactgt tgggaggtaa tgctgcccca cgtgctggtg caggtcagta tcctgggact      960

tggaagctgg caggatttgc cgggtaaagc tgtatgccat catggggcac ctgaaaagaa     1020

aaacacgtct caccactgtg gttgattcaa aagaaagtga ttctattttt taaagaaagc     1080

gttgttaatg taattggtat ccctcctaac tttttgagtt cacaatttac ttggtccaga     1140

gttttctatt cttttttttt tttaaactaa tgaatgacat ttagatactt cataaaatta     1200

tgaacagata tggaggccag agctcatttg ggtaaactta ctcctgctga gttagcaggt     1260

tggtgagaga agctcccctg agctcacctg tctctctgac tgccttggag taggtggcat     1320

aaccttgtgc acagagaact agaaaagggg cagaaccccg gccttgcagt tgtggcaggt     1380

ttccactgtg gtaagctagg ttcattcctc atcaaggaat gtgtagcaga ttgttcactg     1440

tggaggagtt aattatagaa tgggttattg ttgttattct tactcatgaa gttacagatt     1500

ttagccagtc tttgctttta tacttttgtg aaatttaatt tctctctata gcaccttcct     1560

ttttcgtttt cagttatcaa aagtgacttt gacctcataa aagagttgag aacatctctc     1620

gtgtcacata ctgcaggtgc atcagttact tttgcacaga ttctaggggg acatttttct     1680

gaataggaag acaggacaaa gttaacagct taagggctct taattctgtg agttgaggac     1740

ttaaaagtat tgtagcattt gtttggatcc atgaaaaatg tattcagtgg gctttaaaat     1800

ttccatttgc agaatttggt ctctcaggct gtttgggagc tctttttttt acattttttc     1860

tcctttgaca cctattttat tggtgtttaa agtaaaggtt aacatctgta gcttttccag     1920

gttttttttt tttttttttt ttttttggta tgaaattgtc tttctccatt gcagaaataa     1980

gctagggaaa cactaaccca aaaactttct gtagagctgt tcctttggag gcagcatcac     2040

ttattggcag taaagactca gtataaaagc accggcatcc ctacttgggt gatggggatt     2100

aattttatag cattccattt tcctagtgcc acatgtgaaa ttggattttg atgatcttaa     2160

tctatattct acccttataa taaaagatca aaagatatat ctcctatgaa cagattggag     2220

ataggagatg aaaagttggg aggatgtctt tattctaatg tgagggtagg gaaaatgtgg     2280

ataacattac tggggtgagg gaggcattgt tctttagttg gagttctcat tcttattctc     2340

cagtactgac ttgtggggaa agcatacttt ttcactgcca ggtactgaat gcagaggctc     2400

agtgaagtat atatgtggga agtgcatgca tttcgtttat tagcaaacat agctggatta     2460

agacaaagtt gttggtttgg aaaggggtta aagccttaag tgaacaaatc tagctaacag     2520

tgaatgaact aggtaatata acttgcatat ttttaatttc ctttggttaa aggtccccca     2580

tacttctctg ttcggagaca tgagaagtat gattacttca gtgttagttt tcttaatttt     2640

ttttttcccc tatttgtccc ttgtcacttt gttgcaagct agaaatctgt gggttataca     2700

tagggcagct ctttgtgaaa gtggtttatt ccactggaga aaggggattg aaaatcagtt     2760

agaaccaatg tatttcttgc cccacggaac actattccta taagatagct gaaagaagct     2820

gctgtgagga gctcagctcc aaacacagga tcagcacctt gtataggaat tcccatgaat     2880

tatgacttct cattctgttt tatcagagtg catatatgtc ctacttcagg aaaagtaaaa     2940

cagtcattta cgaaagaaag tcaatctgta tcctaagcat tttaataaaa agttaaaaca     3000

aaaaaaaaaa aaaaaaaa                                                   3018


<210>  2151
<211>  4035
<212>  DNA
<213>  homo sapiens

<400>  2151
gtgtagcgcc agcgcgctgt gacgtaatgt gaggggtctc ccggcagggc tgagctggac       60

caatgaggaa aggcaagggg ccgatttgcc tgttctcacg ccccaccctc agacctagcc      120

ggagcaaagt ttcacttata gaagggagag gagcgaacat ggcagcgcgt tggcggtttt      180

ggtgtgtctc tgtgaccatg gtggtggcgc tgctcatcgt ttgcgacgtt ccctcagcct      240

ctgcccaaag aaagaaggag atggtgttat ctgaaaaggt tagtcagctg atggaatgga      300

ctaacaaaag acctgtaata agaatgaatg gagacaagtt ccgtcgcctt gtgaaagccc      360

caccgagaaa ttactccgtt atcgtcatgt tcactgctct ccaactgcat agacagtgtg      420

tcgtttgcaa gcaagctgat gaagaattcc agatcctggc aaactcctgg cgatactcca      480

gtgcattcac caacaggata ttttttgcca tggtggattt tgatgaaggc tctgatgtat      540

ttcagatgct aaacatgaat tcagctccaa ctttcatcaa ctttcctgca aaagggaaac      600

ccaaacgggg tgatacatat gagttacagg tgcggggttt ttcagctgag cagattgccc      660

ggtggatcgc cgacagaact gatgtcaata ttagagtgat tagaccccca aattatgctg      720

gtccccttat gttgggattg cttttggctg ttattggtgg acttgtgtat cttcgaagaa      780

gtaatatgga atttctcttt aataaaactg gatgggcttt tgcagctttg tgttttgtgc      840

ttgctatgac atctggtcaa atgtggaacc atataagagg accaccatat gcccataaga      900

atccccacac gggacatgtg aattatatcc atggaagcag tcaagcccag tttgtagctg      960

aaacacacat tgttcttctg tttaatggtg gagttacctt aggaatggtg cttttatgtg     1020

aagctgctac ctctgacatg gatattggaa agcgaaagat aatgtgtgtg gctggtattg     1080

gacttgttgt attattcttc agttggatgc tctctatttt tagatctaaa tatcatggct     1140

acccatacag ctttctgatg agttaaaaag gtcccagaga tatatagaca ctggagtact     1200

ggaaattgaa aaacgaaaat cgtgtgtgtt tgaaaagaag aatgcaactt gtatattttg     1260

tattacctct ttttttcaag tgatttaaat agttaatcat ttaaccaaag aagatgtgta     1320

gtgccttaac aagcaatcct ctgtcaaaat ctgaggtatt tgaaaataat tatcctctta     1380

accttctctt cccagtgaac tttatggaac atttaattta gtacaattaa gtatattata     1440

aaaattgtaa aactactact ttgttttagt tagaacaaag ctcaaaacta ctttagttaa     1500

cttggtcatc tgattttata ttgccttatc caaagatggg gaaagtaagt cctgaccagg     1560

tgttcccaca tatgcctgtt acagataact acattaggaa ttcattctta gcttcttcat     1620

ctttgtgtgg atgtgtatac tttacgcatc tttccttttg agtagagaaa ttatgtgtgt     1680

catgtggtct tctgaaaatg gaacaccatt cttcagagca cacgtctagc cctcagcaag     1740

acagttgttt ctcctcctcc ttgcatattt cctactgaaa tacagtgctg tctatgattg     1800

tttttgtttt gttgtttttt tgagacggtc tcgctgtgtc acacaggctg gagtgcagtg     1860

gcgtgagctc ggctgactgc aaactctgcc tcccaggttt aagcgattct cctgtcacag     1920

cttcccaagt agctgggatt tacaggtgtg caccgccatg ccaggctaat ttttgtgttt     1980

ttagtagaga cagggtttcg ccaagttgtc caggctggtc ttgaactcct gggctcaagt     2040

gatccgcccg cctcagtctc ccaaagtgcg aggatgacat gtgtgagcta ccacaccagc     2100

aatgtctatg cttctcgata gctgtgaaca tgaaaagaca tctattggga gtccgaggca     2160

ggtggattgc ttgaggccag gagttagaga ccagcctggc caacaaggca aaaccccgtc     2220

tctactaaaa atatgaaaat tagctgggct tggtggctca tgcctataat cctagctact     2280

tgggaggctg aggcacgaga cttgcttaat acctgggagg cggagattgc agtgagccga     2340

gatcacgcta ctgcgctcca gcctgagtga tagagtgaga ctctgtctca aaaaaaagta     2400

tctctaaata caggattata atttctgctt gagtatggtg ttaactacct tgtatttaga     2460

aagatttcag attcattcca tctccttagt tttcttttaa ggtgacccat ctgtgataaa     2520

aatatagctt agtgctaaaa tcagtgtaac ttatacatgg cctaaaatgt ttctacaaat     2580

tagagtttgt cacttattcc atttgtacct aagagaaaaa taggctcagt tagaaaagga     2640

ctccctggcc aggcgcagtg acttacgcct gtaatctcag cactttggga ggccaaggca     2700

ggcagatcac gaggtcagga gttcgagacc atcctggcca acatggtgaa accccgtctc     2760

tactaaaaat ataaaaatta gctgggtgtg gtggcaggag cctgtaatcc cagctacaca     2820

ggaggctgag gcacgagaat cacttgaact caggagatgg aggtttcagt gagccaagat     2880

cacaccactg cactccagcc tggcaacaga gcgagactcc atctcaaaaa aaaaaaaaaa     2940

agtaagaaag aaaaggactc ccttagaatg ggaaagaaaa atcataaaat attgagctga     3000

tgcctgtata tagaaattaa gcgtttctcg aaagctgttc tatgttttgc tgttatttta     3060

gtctttattc tcttccttta ggtggagaaa caaagtacca atttgaaggg atttttttta     3120

ttttgtcttt tggtttctgt cagtagaaat aaccatatgt gctaaccaaa tttctgtgaa     3180

gaatgttttc atggttatca ttatatctaa ctataacctc ccccatagtt atgaagagta     3240

acctgaaatg ccactattgt ggaaatagga taattgtaat tgtgaaaaaa taattttaag     3300

gaaatcttac aagtattaca ttaaaaagat actatgactg ccacctgcca tttaccttct     3360

aataaccctg ccatgtggtt tgcagaaaga gatggatata gtagcctcag aagaaatatt     3420

ttatgtgggt tttttgtttt tcgttactag atttcatgga tgaggggata tggttgacct     3480

tttacttttt aatggagcag ccagtttttg ttaattactc acttgtaaat tgtgagattc     3540

tgaattcctt acctgctatt cttgtacttg tctcaggcca aatctatgct gtggttctta     3600

tgagacttgt atgaagatgc cctgatttgt acagattgac cacgggaata ctactgccat     3660

gtaatctgta tagttccaga taatttgtca tgaacattga cagaatgaca attttttgta     3720

tttgcttttt ctccctttaa gagcacattc ttctgtaagg agaaaggcag cattctggct     3780

aaaatgtgta gaaggtaatt tactacactt ataaaatagt gtgacttttg tgaaaatttt     3840

gaattagctt tcatatgaag tgccttaagt agactcttca tttacttttc tggtaatggt     3900

ttaaatatca tttgttatgc atttttaaga tacagttcag aatgacacat tgtagtggca     3960

aagataacca aatgtctggc tgtttgcttt ttgaccatat caataaactt ttacaatcta     4020

aaaaaaaaaa aaaaa                                                      4035


<210>  2152
<211>  3618
<212>  DNA
<213>  homo sapiens

<400>  2152
aaattttcct ccaggctgtc cttggagaat tccaccctct ttcattctgg ggagaagaag       60

ttaaaattag ggccagccct gcgggactga catgccagat gcagggaagc tgtccccaga      120

aataagcgag ttcccaccgc ggctgggcgg ggcgggagcc tcgggtccca acccagcgga      180

gggactcctg gaaggcctgc cccttccaag tgtctgcaag ggctctggtc ccaagcttta      240

aaatcctgag cgaaggcact gcgggccgac ctctcctctc ccagccagtc gtggctggcc      300

tttcaaagtg tgcagttgtc tcctccctgt ccagccccat cgtcgcccag gaccagctgg      360

gccgcggtct gacctgaggc tgctgctcag cgccggggcg ctggcgctct ccattcgagc      420

accttccagc ataccgctcg gctccgggag ccgctctgca aagttgggca gctcagagcg      480

caagctttgc ctctcgactt ctccctcctt gggtccccgg cgcccccgcc tcccacgatc      540

cctttcacta ggagcagcca gtcccagcgg gctggcaact tgcacccctt cctagtcatc      600

ctccctgaaa cgcgaccatg ctgttaaggg gcgtcctcct ggcgttgcaa gccctgcagc      660

tcgccggtgc cctcgacctg cccgctgggt cctgtgcctt tgaagagagc acttgcggct      720

ttgactccgt gttggcctct ctgccgtgga ttttaaatga ggaaggccat tacatttatg      780

tggatacctc ctttggcaag cagggggaga aagctgtgct gctaagtcct gacttacagg      840

ctgaggaatg gagctgcctc cgtttggtct accagataac cacatcttcg gagtctctgt      900

cagatcccag ccagctgaac ctctacatga gatttgaaga tgaaagcttt gatcgcttgc      960

tttggtcagc taaggaacct tcagacagct ggctcatagc cagcttggat ttgcaaaaca     1020

gttccaagaa attcaagatt ttaatagaag gtgtactagg acagggaaac acagccagca     1080

tcgcactatt tgaaatcaag atgacaaccg gctactgtat tgaatgtgac tttgaagaaa     1140

atcatctctg tggctttgtg aaccgctgga atcccaatgt gaactggttt gttggaggag     1200

gaagtattcg gaatgtccac tccattctcc cacaggatca caccttcaag agtgaactgg     1260

gccactacat gtacgtggac tcagtttatg tgaagcactt ccaggaggtg gcacagctca     1320

tctccccgtt gaccacggcc cccatggctg gctgcctgtc attttattac cagatccagc     1380

aggggaatga caatgtcttt tccctttaca ctcgggatgt ggctggcctt tacgaggaaa     1440

tctggaaagc agacaggcca gggaatgctg cctggaacct tgcggaggtc gagttcagtg     1500

ctccttaccc catggaggtt atttttgaag ttgctttcaa tggtcccaag ggaggttatg     1560

ttgccctgga tgatatttca ttctctcctg ttcactgcca gaatcagaca gaacttctgt     1620

tcagtgccgt ggaagccagc tgcaattttg agcaagatct ctgcaacttt taccaagata     1680

aagaaggtcc aggttggacc cgagtgaaag taaaaccaaa catgtatcgg gctggagacc     1740

acactacagg cttagggtat tacctgctag ccaacacaaa gttcacatct cagcctggct     1800

acattggaag gctctatggg ccctccctac caggaaactt gcagtattgt ctgcgttttc     1860

attatgccat ctatggattt ttaaaaatga gtgacaccct agcagtttac atctttgaag     1920

agaaccatgt ggttcaagag aagatctggt ctgtgttgga gtccccaagg ggtgtttgga     1980

tgcaagctga aatcaccttt aagaagccca tgcctaccaa ggtggttttc atgagcctat     2040

gcaaaagttt ctgggactgt gggcttgtag ccctggatga cattacaata caattgggaa     2100

gctgctcatc ttcagagaaa cttccacctc cacctggaga gtgtactttc gagcaagatg     2160

aatgtacatt tactcaggag aaaagaaacc ggagcagctg gcacaggagg aggggagaaa     2220

ctcccacttc ctacacagga ccaaagggag atcacactac tggggtaggc tactacatgt     2280

acattgaggc ctcccatatg gtgtatggac aaaaagcacg cctcttgtcc aggcctctgc     2340

gaggagtctc tggaaaacac tgcttgacct ttttctacca catgtatgga gggggcactg     2400

gcctgctgag tgtttatctg aaaaaggaag aagacagtga agagtccctc ttatggagga     2460

gaagaggtga acagagcatt tcctggctac gagcactgat tgaatacagc tgtgagaggc     2520

aacaccagat aatttttgaa gccattcgag gagtatcaat aagaagtgat attgccattg     2580

atgatgttaa atttcaggca ggaccctgtg gagaaatgga agatacaact caacaatcat     2640

caggatattc tgaggactta aatgaaattg agtattaaga aatgatctgc attggattta     2700

ctagacgaaa accatacctc tcttcaatca aaatgaaaac aaagcaaatg aatactggac     2760

agtcttaaca attttataag ttataaaatg actttagagc accctccttc attacttttg     2820

caaaaacata ctgactcagg gctctttttt tctttttgca tatgacaact gttactagaa     2880

atacaggcta ctggttttgc atagatcatt catcttaatt ttggtaccag ttaaaaatac     2940

aaatgtacta tattgtagtc attttaaagt acacaaaggg cacaatcaaa atgagatgca     3000

ctcatttaaa tctgcattca gtgaatgtat tgggagaaaa ataggtcttg caggtttcct     3060

tttgaatttt aagtatcata aatattttta aagtaaataa tacggggtgt cagtaatatc     3120

tgcagaatga atgcagtctt tcatgctaat gagttagtct ggaaaaataa agtcttattt     3180

tctatgtttt attcatagaa atggagtatt aatttttaat attttcacca tatgtgataa     3240

caaaggatct ttcatgaatg tccaagggta agtcagtatt aattaatgct gtattacaag     3300

gcaatgctac cttctttatt ccccctttga actacctttg aagtcactat gagcacatgg     3360

atagaaattt aacttttttt tgtaaagcaa gcttaaaatg tttatgtata catacccagc     3420

aacttttata aatgtgttaa acaattttac tgatttttat aataaatatt ttggtaagat     3480

tttgaataat atgaattcag gcagatatac taaactgctt ttatttactt gtttagaaaa     3540

ttgtatatat atgtttgtgt atcctaacag ctgctatgaa attataaaat tacctaataa     3600

aaataatttg aaaatctt                                                   3618


<210>  2153
<211>  4063
<212>  DNA
<213>  homo sapiens

<400>  2153
cctcgtccca ggctgcaacg gaggcagagc caacgcctcg cgggcttcca cgtacgcact       60

ccaacgcgtg ttcccggaga agaacgcatc cgggtcacgg gagccggtgt ctcaggctcc      120

gccccttcac cccccgaaag gctaatcccc acttccgacc ctctcaggcc ttttccgctt      180

ctcttttacc tccccaggtc cgcccgtctg cgcccctcac aggaagccgg agggtcgctc      240

tgatcccgaa tctcccacag gcgtgaacct gctctgctgt gtatctttgc ggggtggcct      300

gcgctgaggc ctgccgcgcg cggtgagtcc gcgcagacct gaccctgcgt ctcgcagctc      360

ggttgaggcc gccgccgcct tctcgggatg ccgcggccgg ggtccgcgca gcgctgggcg      420

gccgtcgcgg gccgttgggg gtgcaggctg ctcgcactgc tgctactggt gcctggaccc      480

ggcggcgcct ctgagatcac cttcgagctt cctgacaacg ccaagcagtg cttctacgag      540

gacatcgctc agggcaccaa gtgcaccctg gagttccagg tgattactgg tggtcactat      600

gatgtagatt gtcgattaga agatcctgat ggtaaagtgt tatacaaaga gatgaagaaa      660

cagtatgata gttttacctt cacagcctcc aaaaatggga catacaaatt ttgcttcagc      720

aatgaatttt ctactttcac acataaaact gtatattttg attttcaagt tggagaagac      780

ccacctttgt ttcctagtga gaaccgagtc agtgctctta cccagatgga atctgcctgt      840

gtttcaattc acgaagctct gaagtctgtc atcgattatc agactcattt ccgtttaaga      900

gaagctcaag gccgaagccg agcagaggat ctaaatacaa gagtggccta ttggtcagta      960

ggagaagccc tcattcttct ggtggttagc atagggcagg tatttctttt gaaaagcttt     1020

ttctcagata aaagaaccac cacaactcgt gttggatcat aactacgttt tgagaattga     1080

tgcaccattg ccactgtaat attgctgtcc tctaattaat tttaggtact gaagaactta     1140

atattggcaa catttttaaa tccttactca tacacttgtt gggagggatg tacaatgcat     1200

attcccaaac tgtggaaagg acaccttttt ttatttgtaa aggtggaaaa actttggaac     1260

tcattttggg ctattcatgt taaatattca acaccaatga tctactctgt tcgcagttgt     1320

ttatatctac tcttcgcaca ctaaactttg gtattttgat tccttttaac catttaagac     1380

tacttttctt ataggtagtt gatattttaa aaactttaga tttaatgtct acatgtgtta     1440

gggaggaaga aaattgcctt ttaattgtta ataagaaaac caaatgtgat gaactgtagc     1500

ccaagcccta ttctgcactg ttcagtttta tggaggaaaa ataaatctac cataggaatg     1560

ttagttaata ttgatatatc atggtaaaat tgatttctca ctagcttaga aaatgtcaga     1620

cttttgtttt tggggtttat aatttaaacc agctatgcta ttttttcata aaggcatttg     1680

tagtacacag aaaacagtag tttcagtagt gtaaaagagt ttatacaggc cttaaatatc     1740

agactttgta acaggtagaa atattacaga ataatttaag acactacaat gggggcaaat     1800

gaaataggaa aatttttagt gagttacacg tactcattac attttcagtg cttttacaag     1860

gaaaaaaggt gatatgttta attttaaaat tttaattggc tagctcttgc ccttatatga     1920

ctttaatgtc tgtgagtcat tcccagctta aattaacaat tgttagtatt agtctcacac     1980

ataagtgcca tacattttat cctcatggat gtgatgcact gaaaagttag ttgctctcct     2040

tttttctttt ttttgtcgtg catattttat ttctgtagtt tctggttagc taccctaaag     2100

tgatttaaaa atttagaatg ctttgtgttt cctatttggt aatcttcatt gacttttctt     2160

tagttaatga gtattaaata gtgcatattc tgtagactat agggtttaca ttgtgttgca     2220

tcttataact tgtatagatt gagctgattg aaataagatt ttgttccaag tattatctga     2280

tagaatacaa gatgattcaa aattatatag atatttaaag cttttctgct gttttttttt     2340

tttttaattg caactgcttt tctgccgtgc ctctcttccc tacccaaaag tgatgagttc     2400

tgaacaagac aagactgtca tattgtagag actttggtat gtgataccat agaatactga     2460

ttggatagcc atcctagtca cttaccaata ctgactagaa gttaactctt aattctaagc     2520

tatcttaaaa tgcatatata tacttcttgc atggaagagc aaaacaaatt caagttgtca     2580

tgcctgataa tttcagatgc caccgtatag caaagggtga acatgttttc aaccctttaa     2640

ctttttacgg tgtttgaaga ccagctactc cttaatattt atcaatggat taagaagttt     2700

aagattttgc agatttatca atttgggttt ttgtactgaa gttgtcttgc ggctttgcaa     2760

gtgtcccttt atatttaaat ttgaaagttg taagcactga tgttaatgtg attgatcagc     2820

atgggcatat gtaaaatgtc cttttctggt tgcctctcta tgctattgtg ttcagatact     2880

tacaccataa ttaaacagta agttatagac ttgctgagtt tggcatagat agtgcactca     2940

tttaatctgt gcctctcaaa acttcagaat attagcatat taccacaaat aatttttggt     3000

gaaactattg agatattaaa atttttgaaa tcactactgt tacctgttat agaaaatagt     3060

gttggcttag tctagtctct gtgtaactgg ttacattttg atggttgtct atactcaact     3120

ggatatgtgt atgtaaatta gaaaatacat acctatccag acataaatgc taagtaacat     3180

ttttttcttc ctccaactac ataatttgta gctcatcatt tttccttaat cctttcctaa     3240

cttgttgcag cagtttgaat ttcccagata tttatgtttg aacataatgg ctcagaatac     3300

atatttgaac atcatagttg tatatatttt taaagtagaa taaataatgg aaagcaactt     3360

gatatacaag tttatactaa aatttcaact gtgtgaagat acattttaag gcattacttt     3420

gctaataatc tacacattct tttttctatt aaataaacaa atggtttgtg gttcacagct     3480

ttcatccaag cttggtgata atcaattttg aaaatacagt ggactgaaaa gcaaatttat     3540

tctttcgaag atttcattta aatctctgta ctatgcattt ttgtttcagt ttgtaaatgt     3600

gtaacattta tagttaaata ggacaaagca ggccctatga ctattgtttt caaaaaatta     3660

atatataaat aattcagagg ggtttttcat ttacttttga aaagaaattt ctttaacagg     3720

attgcaccta tcaatttctt gtagaataaa aaaaaatctt tcaacaaact gactttactt     3780

gtttctgtca ggatttaaat ctttctaaag ctccttataa acttaaagcc tagagtacag     3840

ttctgtaatg agagtgatta tttatttggt attttattaa aatatctgag ggactgtcca     3900

agaaagaagg tgaaagagaa ataccacgtc tgtactgcct aatttgtaac cttctctttg     3960

cattccttac tgaaagtttg tgtaggtgaa aagcagttaa atcatcagtt gctctaaaga     4020

ggtcttaatt tttaagtaaa ttacctttag tttgtatatt acc                       4063


<210>  2154
<211>  1974
<212>  DNA
<213>  homo sapiens

<400>  2154
acaaagaaag tcatttaagc ccctttacag accagctctg ctgggaggat gcagaaataa       60

atgatcagcg tcccggcgtg agagagctgc ccccagaagt ggccggggga gaaaagggtg      120

aagaggagct aaagcttagg aggcgatttc cacggaaatg gatgctccct aaggatgtgc      180

ggaaagggga tgggaatgtg cggattgggg gcgggggcac caacgcactc cggcgggcaa      240

gcggtctccc gcaccacctg ctgcaaggct cgggaaggaa ggcgaagata gcaccggggc      300

atccccggga gtccgcaagg ctttgcgctg caaatccagt gctaccagtg tgaagaattc      360

cagctgaaca acgactgctc ctcccccgag ttcattgtga attgcacggt gaacgttcaa      420

gacatgtgtc agaaagaagt gatggagcaa agtgccggga tcatgtaccg caagtcctgt      480

gcatcatcag cggcctgtct catcgcctct gccgggtacc agtccttctg ctccccaggg      540

aaactgaact cagtttgcat cagctgctgc aacacccctc tttgtaacgg gccaaggccc      600

aagaaaaggg gaagttctgc ctcggccctc aggccagggc tccgcaccac catcctgttc      660

ctcaaattag ccctcttctc ggcacactgc tgaagctgaa ggagatgcca ccccctcctg      720

cattgttctt ccagccctcg cccccaaccc cccacctccc tgagtgagtt tcttctgggt      780

gtccttttat tctgggtagg gagcgggagt ccgtgttctc ttttgttcct gtgcaaataa      840

tgaaagagct cggtaaagca ttctgaataa attcagcctg actgaatttt cagtatgtac      900

ttgaaggaag gaggtggagt gaaagttcac ccccatgtct gtgtaaccgg agtcaaggcc      960

aggctggcag agtcagtcct tagaagtcac tgaggtgggc atctgccttt tgtaaagcct     1020

ccagtgtcca ttccatccct gatgggggca tagtttgaga ctgcagagtg agagtgacgt     1080

tttcttaggg ctggagggcc agttcccact caaggctccc tcgcttgaca ttcaaacttc     1140

atgctcctga aaaccattct ctgcagcaga attggctggt ttcgcgcctg agttgggctc     1200

tagtgactcg agactcaatg actgggactt agactggggc tcggcctcgc tctgaaaagt     1260

gcttaagaaa atcttctcag ttctccttgc agaggactgg cgccgggacg cgaagagcaa     1320

cgggcgctgc acaaagcggg cgctgtcggt ggtggagtgc gcatgtacgc gcaggcgctt     1380

ctcgtggttg gcgtgctgca gcgacaggcg gcagcacagc acctgcacga acacccgccg     1440

aaactgctgc gaggacaccg tgtacaggag cgggttgatg accgagctga ggtagaaaaa     1500

cgtctccgag aaggggagga ggatcatgta cgcccggaag taggacctcg tccagtcgtg     1560

cttgggtttg gccgcagcca tgatcctccg aatctggttg ggcatccagc atacggccaa     1620

tgtcacaaca atcagccctg ggcagacacg agcaggaggg agagacagag aaaagaaaaa     1680

cacagcatga gaacacagta aatgaataaa accataaaat atttagcccc tctgttctgt     1740

gcttactggc caggaaatgg taccaatttt tcagtgttgg acttgacagc ttcttttgcc     1800

acaagcaaga gagaatttaa cactgtttca aacccggggg agttggctgt gttaaagaaa     1860

gaccattaaa tgctttagac agtgtattta taccagttga tgtctgttaa ttttaaaaaa     1920

atgttttcat tggtgtttgt ttgcgtatcc agaaagcagt tcatgttatc cata           1974


<210>  2155
<211>  3951
<212>  DNA
<213>  homo sapiens

<400>  2155
agaacaaact cctacctctg tttgcaacta agagttacat cccccatgcc aagaccttcc       60

gaggcgtccc agagggggaa attcctcgct gccggactgc gcccaccctt gaggacctca      120

cattctcttt gggcagagcg gaagccagac agagacaggg actacgaagc gacaatcccc      180

agccctgtgt gtgcaaggag cccccgaggg gcaggcagcc acgctgcaga aggctagact      240

ctccgacccc cagggagcct ggtgtgggct gcagggacag aacgcttctc agaggaggtt      300

ctctacttaa aagacaatga ctactgatga aggtgccaag aacaatgaag aaagccccac      360

agccactgtt gctgagcagg gagaggatat tacctccaaa aaagacaggg gagtattaaa      420

gattgtcaaa agagtgggga atggtgagga aacgccgatg attggagaca aagtttatgt      480

ccattacaaa ggaaaattgt caaatggaaa gaagtttgat tccagtcatg atagaaatga      540

accatttgtc tttagtcttg gcaaaggcca agtcatcaag gcatgggaca ttggggtggc      600

taccatgaag aaaggagaga tatgccattt actgtgcaaa ccagaatatg catatggctc      660

ggctggcagt ctccctaaaa ttccctcgaa tgcaactctc ttttttgaga ttgagctcct      720

tgatttcaaa ggagaggatt tatttgaaga tggaggcatt atccggagaa ccaaacggaa      780

aggagaggga tattcaaatc caaacgaagg agcaacagta gaaatccacc tggaaggccg      840

ctgtggtgga aggatgtttg actgcagaga tgtggcattc actgtgggcg aaggagaaga      900

ccacgacatt ccaattggaa ttgacaaagc tctggagaaa atgcagcggg aagaacaatg      960

tattttatat cttggaccaa gatatggttt tggagaggca gggaagccta aatttggcat     1020

tgaacctaat gctgagctta tatatgaagt tacacttaag agcttcgaaa aggccaaaga     1080

atcctgggag atggatacca aagaaaaatt ggagcaggct gccattgtca aagagaaggg     1140

aaccgtatac ttcaagggag gcaaatacat gcaggcggtg attcagtatg ggaagatagt     1200

gtcctggtta gagatggaat atggtttatc agaaaaggaa tcgaaagctt ctgaatcatt     1260

tctccttgct gcctttctga acctggccat gtgctacctg aagcttagag aatacaccaa     1320

agctgttgaa tgctgtgaca aggcccttgg actggacagt gccaatgaga aaggcttgta     1380

taggaggggt gaagcccagc tgctcatgaa cgagtttgag tcagccaagg gtgactttga     1440

gaaagtgctg gaagtaaacc cccagaataa ggctgcaaga ctgcagatct ccatgtgcca     1500

gaaaaaggcc aaggagcaca acgagcggga ccgcaggata tacgccaaca tgttcaagaa     1560

gtttgcagag caggatgcca aggaagaggc caataaagca atgggcaaga agacttcaga     1620

aggggtcact aatgaaaaag gaacagacag tcaagcaatg gaagaagaga aacctgaggg     1680

ccacgtatga cgccacgcca aggagggaag agtcccagtg aactcggccc ctcctcaatg     1740

ggctttcccc caactcagga cagaacagtg tttaatgtaa agtttgttat agtctatgtg     1800

attctggaag caaatggcaa aaccagtagc ttcccaaaaa cagcccccct gctgctgccc     1860

ggagggttca ctgaggggtg gcacgggacc actccaggtg gaacaaacag aaatgactgt     1920

ggtgtggagg gagtgagcca gcagcttaag tccagctcat ttcagtttct atcaaccttc     1980

aagtatccaa ttcagggtcc ctggagatca tcctaacaat gtggggctgt taggttttac     2040

ctttgaactt tcatagcact gcagaaacct ttaaaaaaaa aatgcttcat gaatttctcc     2100

tttcctacag ttgggtaggg taggggaagg aggataagct tttgtttttt aaatgactga     2160

agtgctataa atgtagtctg ttgcattttt aaccaacaga acccacagta gaggggtctc     2220

atgtctcccc agttccacag cagtgtcaca gacgtgaaag ccagaacctc agaggccact     2280

tgcttgctga cttagcctcc tcccaaagtc cccctcctca gccagcctcc ttgtgagagt     2340

ggctttctac cacacacagc ctgtccctgg gggagtaatt ctgtcattcc taaaacaccc     2400

ttcagcaatg ataatgagca gatgagagtt tctggattag cttttcctat tttcgatgaa     2460

gttctgagat actgaaatgt gaaaagagca atcagaattg tgctttttct cccctcctct     2520

attcctttta gggaataata ttcaatacac agtacttcct cccagcattg ctactgctca     2580

gcttcttctt tcattctaat ccttgctatt aagaatttaa gacttgtgct tacaatattt     2640

ttgacctgga gtggatctat ttacatagtc atttaggatc catgcagctt tttttgtctt     2700

tttaagatta ttggctcata agcatatgta tactggttta tggaacttta tttacactcc     2760

tctatcatgc aaaaaaattt tgacttttta gtactaagct taatttttaa aaacaaaatc     2820

tgtagggttg acaaataaat agttgctctt ctacactagg ggtttcacct gcaggtttga     2880

cacgcagttg ctcgcttttc ctgccctgtc aagcttctct gttctggcgt gagttgtgaa     2940

agagttgaag acagcttccc atgccggtac acagccagta gcctaaatct ccagtacttg     3000

agctgaccat tgaactaggg caagtcttaa atgtgtacat gtagttgaat ttcagtcctt     3060

acgggtaaac agattgagca tggctctcta ttccctcagc ctaagaaaca ctcatgggaa     3120

tgcatttggc aacccaagga accatttgct taaacctgga acatctcacc tttttaaatc     3180

ctaaaaaaca ctggcagtta tattttaaat tagtttttat ttttatgatg gttttatcaa     3240

aagactttta ttattagatt gggaccccct tcaaacctaa aaatcaagtt atttcctttt     3300

ataatacttt tcttccccat ggaacaaatg ggatcaattt gtgagttttt tcctttaatg     3360

ataactaaaa tccctctaat ttctcattta tgcttttgtc ttttttatga aatatttctt     3420

ttaaaagccc cagtctcacc tacgaaatat gaagagcaaa agctgatttt gcttacttgc     3480

taaactgttg ggaaagctct gtagagcatg gttccagtga ggccaagatt gaaatttgat     3540

actaaaaagg ccacctagct ttttgcagat aacaaacaag aaagctattc caagactcag     3600

atgatgccag ctgtctccca cgtgtgtatt atggttcacc agggggaact ggcaaaagtg     3660

tgtgtgggga ggggaagggt gtgtgagtgg ttctgagcaa ataactacag ggtgcccatt     3720

accactcaag aagacacttc acgtattctt gtatcaaatt caataatctt aaacaatttg     3780

tgtagaagtc cacagacatc tttcaaccac cttttaggct gcatatggat tgccaagtca     3840

gcatatgagg aattaaagac attgttttta aaaaaaaaaa atcatttaga tgcacttttt     3900

tgtgtgttct ttaaataaat ccaaaaaaaa tgtgacttcc aaaaaaaaaa a              3951


<210>  2156
<211>  3745
<212>  DNA
<213>  homo sapiens

<400>  2156
gcggccgccc aggctgcccc cgcccgcgcg cgcccgttgg ggggcccggg gagcggcgcc       60

cgcggccggg ccgcattgtg acgtagcggg gccgcggcag cgcctccacc gcccgcctac      120

ttcggctgag gctgttctgc tcctgccgct gcggtccgtc ggtcggtcag tcagtccctt      180

cgcgctcctg agccgccggc gcgccgggcg ccccgggaat ttataagtat ttgaccgtac      240

tcaaaatgtg caaggaagaa taatggaagc ccctgaatac cttgatttgg atgaaattga      300

ctttagtgat gacatatctt attcagtcac atcactcaag acgatcccag aactgtgccg      360

aagatgtgat acgcaaaacg aagacagatc agtttctagc tctagctgga attgtggcat      420

ctcaactctt attacaaaca cgcaaaagcc cacaggaatc gctgatgtgt acagtaagtt      480

ccgcccagtg aagcgggttt cgccactgaa acatcagcca gagactctgg agaacaatga      540

aagtgatgac caaaagaacc agaaagtggt tgagtaccag aaagggggtg agtctgacct      600

gggcccccag cctcaggagc ttggccctgg agatggagtg ggcggcccac caggtaagag      660

ctctgagccc agcacatcgc tgggtgaact ggagcactac gacctcgaca tggatgagat      720

tctggatgtg ccttatatta aatccagtca gcagcttgcc tcttttacca aggtgacttc      780

agaaaaaaga attttgggct tatgcacaac catcaatggc ctttctggca aagcctgctc      840

tacaggaagt tctgagagct catcatccaa catggcacca ttttgtgttc tttctcccgt      900

gaaaagccct cacttgagaa aagcatcagc tgtcatccac gaccagcaca agctgtccac      960

tgaagaaacc gagatctcac ctcctctggt taaatgtggc tctgcatatg agcctgaaaa     1020

ccagagtaaa gacttcctaa acaagacatt tagtgatcct catggtcgaa aagttgagaa     1080

gacaacacca gactgccagc tcagggcctt ccacctacaa tcctcagcag cagaatccaa     1140

accagaagag caggtcagtg gcctaaaccg gaccagctcc caaggcccag aagaaaggag     1200

tgagtatctg aaaaaagtga aaagcatctt gaacattgtt aaagaaggac agatctctct     1260

cctgccacac ctagctgcag acaatctaga caaaattcac gacgaaaatg gaaacaatct     1320

attacatatt gcggcgtcac agggacacgc agagtgtcta cagcacctca cttctttgat     1380

gggagaagac tgcctcaatg agcgcaacac tgagaagttg actccagcag gcctggccat     1440

taagaatggt cagttggagt gcgtacgctg gatggtgagc gaaacagaag ccattgcaga     1500

actgagttgt tctaaggatt ttccaagcct tattcattac gcaggttgct atggccagga     1560

aaagattctt ctgtggcttc ttcagtttat gcaagaacag ggcatctcgt tggatgaagt     1620

agaccaggat ggcaacagtg ccgttcacgt agcctcacag catggctacc ttggatgcat     1680

acagaccttg gttgaatatg gagcaaatgt caccatgcag aaccacgctg gggaaaagcc     1740

ctcccagagc gccgagcggc aggggcacac cctgtgctcc aggtacctgg tggtggtgga     1800

gacctgcatg tcgctggcct ctcaagtggt gaagttaacc aagcagctaa aggaacaaac     1860

agtagaacgt gtcacgctgc agaaccaact ccaacaattt ctagaagccc agaaatcaga     1920

gggcaagtca ctcccttctt cacccagttc accatcctca cctgcctcca gaaagtccca     1980

gtggaaatct ccagatgcag atgatgattc tgtagccaaa agcaagccag gagtccaaga     2040

ggggattcag gttcttggaa gcctgtcagc ctccagccgg gctagaccca aagcaaaaga     2100

tgaagattct gataaaatct tacgccagtt attgggaaag gaaatctcag aaaatgtctg     2160

cacccaggaa aaactgtcct tggaattcca ggatgctcag gcttcctcta gaaattctaa     2220

aaagatccca ctggagaaga gggaactgaa gttagccagg ctgagacagc tgatgcagag     2280

gtcactgagt gagtctgaca cagactccaa caactctgag gaccccaaga ctaccccagt     2340

gaggaaggct gaccgaccaa ggccgcagcc cattgtagaa agcgtagaga gtatggacag     2400

cgcagaaagc ctgcacctga tgattaagaa acacaccttg gcatcagggg gacgcaggtt     2460

tcctttcagc atcaaggcct ccaaatccct ggatggccac agcccatctc ccacctcaga     2520

gagcagcgaa ccagacttag aatcccagta tccaggctca gggagtattc ctccaaacca     2580

gccctctggt gaccctcagc agcccagccc tgacagtact gctgcccaga aagttgccac     2640

aagtcccaag agtgccctca agtctccatc ttccaagcgt aggacatctc agaacttaaa     2700

actgagagtt acctttgagg agcctgtggt gcagatggag cagcctagcc ttgaactgaa     2760

tggagaaaaa gacaaagata agggcaggac tctccagcgg acctccacaa gtaacgaatc     2820

gggggatcaa ctgaaaaggc cttttggagc ctttcgatct atcatggaga cactaagtgg     2880

caaccaaaac aataataata actaccaggc agccaaccag ctgaaaacct ctacattgcc     2940

cttgacctca cttgggagga agacagatgc caagggaaac cctgccagct ccgctagcaa     3000

aggaaagaat aaggcagcat aatgacatca atagaaaaat gaagaaatcc tacagcataa     3060

agcacattgc tgagccagag tcaaaagaac tcttcttgta aatcactttt taaattttct     3120

ctcactgatg ccctttggaa attattggaa atttctggac tatcctcttt ggaaagagaa     3180

ccatgaaaac aatgcctcac cagcagaaga acagaatatc aggatgcctt aaatttatag     3240

tagtagactg taaaagattc attttggggt gatatctgta tatataactt gtttttttaa     3300

aagatgccgt ttaaaagcat gattgggaaa atgtatgttt tttaagagta gattgattca     3360

ccctacccac aggacattca ccaagccact gataccattt tatatttcat caattgcatg     3420

agtatttgct aatgttgatt gaacctccct ttccccataa tgtgggcaga tttggctcag     3480

ctccttcatg agatcaggtc agtggtattg tttctgtcaa gagtgttttt tctgtcattt     3540

ctactttttg tataaaggaa ataaaacaat gttaacagcc acctataagc ttggggcacc     3600

tactttctaa caaatctgtg atgttctgat ttctaaggga ctttgcaagt attttgattg     3660

ctgatatttg atttcaggaa caaactgctc agtttagcag ttttcccata ggcgtcaaat     3720

aaaacattct atatttcatt aagta                                           3745


<210>  2157
<211>  1236
<212>  DNA
<213>  homo sapiens

<400>  2157
aagggcgctc cgcgagcccg tctctcctcg aatgaaagga aacaacctcc ggcgacagag       60

ccccgctctc aggcactgct ggagaaccga gaccgacttc tttctcttta ccctcattgg      120

cgcttctctc ctgcagtccg cctctgggcc ctgccgcatt tcttgagact taaagtggca      180

ttctaaaggc aatttaaaaa tcatgtcaag ctcagttgaa cagaaaaaag ggcctacaag      240

acagcgcaaa tgtggctttt gtaagtcaaa tagagacaag gaatgtggac agttactaat      300

atctgaaaac cagaaggtgg cagcgcacca taagtgcatg ctcttttcat ctgctttggt      360

atcatcacac tctgataatg aaagtcttgg tggattttct attgaagatg tccaaaagga      420

aattaaaaga ggcacgaagc tgatgtgttc tttgtgccat tgtcctggag caacaattgg      480

ttgtgatgtg aaaacatgtc acaggacata ccactaccac tgtgcattgc atgataaagc      540

tcaaatacga gagaaacctt cacaaggaat ttacatggtc tattgccgaa aacacaagaa      600

aactgcacat aactccgaag cagctgattt agaagaaagt tttaatgaac atgaactgga      660

gccctcatca cctaaaagta aaaagaaaag tcgcaaagga aggccaagaa aaactaattt      720

taaagggctg tcagaagata ccaggtccac atcctcccat ggaacagatg aaatggaaag      780

tagttcctat agagataggt ctccacacag aagcagccct agtgacacca ggcctaaatg      840

tggattttgc catgtagggg aggaagaaaa tgaagcacga ggaaaactgc atatatttaa      900

tgccaagaag gcagctgccc attataagtg catgttgttt tcttctggca cagtccagct      960

cacaacaaca tcaagagcag aatttggaga ctttgatatt aaaactgtac ttcaggagat     1020

taaacgagga aaaagaatgg tctgtagttt ttatatttgt tatgcaacat tacacttgat     1080

ttgctgcttt aaatttagag tacatcccaa atttatccag tcatcagaaa atttaaagta     1140

gttcgtatgt taaagcaaag tatatatttg acttatttgt aatataataa aggatgctga     1200

tgttactgaa aaaaaaaaaa aaaaaaaaaa aaaaaa                               1236


<210>  2158
<211>  1144
<212>  DNA
<213>  homo sapiens

<400>  2158
ttcccacgcg ccggccccgt tgcccccgcg cgcgcgcaca ctcgcgagcc ccggcgacat       60

gcaaatgagc tggctccagt gcccagaccc aagcccccca ctgctcaatg gacaccccca      120

gcccagaccc gttgccttcg cctttgcccg gggaggaaga gaaacctctg gccttatctc      180

ctcctgttcc ccggggccgc cgaggccgtc gtcctggggg agccacctcc tcaaatcgga      240

cactcaaggc ctccctccct cgcaagcggg gccgcccccc caagtcaggg caggagcccc      300

cactggtgca ggtgcagggg gtgacagccc cagtaggcag cagtggcggg agcgacctcc      360

tcctgatcga tgatcagggt gtgccctata cggtctctga aggttcagcg gctgggcctg      420

agggctctgg ccccaggaag gccccacact tctgcccggt gtgcctgcgg gccttcccct      480

acctctccga cctggagcgc cacagcatct cgcactcaga gctgaagccg caccagtgca      540

aggtttgcgg caagaccttc aagcgctcca gccacctgcg gcggcactgc aacatccatg      600

ccggcctgcg gcccttccgc tgcccgctgt gcccccgccg cttccgcgag gcgggcgagc      660

tggcgcacca ccaccgcgtg cactcggggg agcgcccgta ccagtgcccc atctgccggc      720

tgcgctttac agaggccaac acgctccggc gccatgcgaa gcgcaagcac ccggaggcca      780

tgggggtacc cctgtgtgca ccagatccag ggtctgaacc gccgtgggac gaggagggca      840

tcccggccac agcaggggcc gaggaggagg aggagacaga ggggaaaggg gagccggcct      900

gacccacacc cccggccatc gctccctggg ccaggtttag agcagggagt ttggctggtg      960

ctgggcctga gccagggggc cgggacaccc ttgtttccgg tggtcttccc gttgtgggag     1020

caggtggagg gtggagacct aaactttggg gtccagctgc cttcagcccc cctcccccag     1080

actaacagac ccttggaggc aggggctgtg gaaataaatc tctgcctgct ggcaaaaaaa     1140

aaaa                                                                  1144


<210>  2159
<211>  3615
<212>  DNA
<213>  homo sapiens

<400>  2159
gtctttacgt agacgtcggg ggcgcagccg cgctgtgcgc ggtgactggc ggctgcactg       60

gcggcagctg gaggtgtaat agtgcgggta gtgggtttgg agaagttccg aggcggcggt      120

ggcgccggtc aggacaagga tagcggaacc gggccctggg cttgtcgctc accatgccga      180

cagtagagga gctttaccgc aattatggca tcctggccga tgccacggag caagtgggcc      240

agattcgacg tcaagcaatt aaagaactgc ctcaatttgc cactggagaa aatcttcctc      300

gagtggcaga tatactaacg caacttttgc agacagatga ctctgcagaa tttaacctag      360

tgaacaatgc cctattaagt atatttaaaa tggatgcaaa agggacttta ggtgggttgt      420

tcagccaaat acttcaagga gaggacattg ttagagaacg agcaattaaa ttcctttcta      480

caaaacttaa gactttacca gatgaagtct taacaaagga agtggaagag cttatactaa      540

ctgaatccaa aaaggtccta gaagatgtga ctggtgaaga atttgttcta tttatgaaga      600

tactgtctgg gttaaaaagc ttacagacag tgagtggaag acagcaactt gtagagttgg      660

tggctgaaca ggccgaccta gaacagacct tcaatccctc ggatcctgac tgtgtggaca      720

ggctcttaca gtgcactcgg caggcagtac ccctcttctc taaaaatgtc cattccacaa      780

ggtttgtgac atatttctgt gagcaggttc tccctaacct cggtaccttg actaccccag      840

tggaaggtct tgatatacag ttggaggtat tgaaattgtt ggcggagatg agttcatttt      900

gtggtgacat ggaaaaacta gaaacaaatt taaggaaact atttgataag ttattggaat      960

acatgcccct ccctccagaa gaggcagaaa atggagagaa tgctggtaat gaagaaccca     1020

agctacagtt cagttatgtg gaatgtttgt tgtacagttt tcaccagttg ggccgaaaac     1080

ttccagattt cttaacagcc aaactgaatg cagaaaagct caaagatttc aaaatcaggc     1140

tgcagtactt tgcacggggc ctgcaagttt atatcagaca acttcgctta gctctccagg     1200

gtaaaacggg tgaggcctta aaaacagaag agaacaagat taaagtcgtt gcattgaaaa     1260

taacaaacaa tatcaatgtt ttaatcaagg atctcttcca cattcctcct tcttataaga     1320

gcacagtaac actatcctgg aaacctgtac aaaaggttga gattgggcaa aagagagcca     1380

gtgaagatac aacttcaggt tcaccaccca agaaatcttc agcaggacca aaaagagatg     1440

ccaggcagat ttataaccct cccagtggga aatatagcag caatttgggc aactttaatt     1500

atgagaggag ccttcagggg aagtagaggt ggccgaggtt ggggcacacg aggaaatcgt     1560

agtcggggaa gactctactg aataagacat cagcattctt cagcattgtc atgagcttaa     1620

tatacttaaa ttctactact cattggattg ccggggatgt ccctttaaac agactgctgc     1680

cttcagctaa aaacttaatg ttctttatac ctttgtatgt atgacctact tttgtaacag     1740

accatggttg tgtccaaggt aaaaccacag tgatattttt ggatgctttg tctgcaatct     1800

tgacttgttt ttgcagtatc attattcaga cttcaaattg tgaatctttt aaacatcttg     1860

ataatttgtt gttgagagct gttcattcta aaatgtaatg aaattcagtc tagttctgct     1920

gataaagatc atcagttttg aaaggttact gattttcctc ttccctctta gttttttacc     1980

caatatatgg agaagagtaa tggtcaatct taacattttg ttttaattgt ttaataaagc     2040

tgctgggcag tggtgcagca ttcctaccta gtgtcataaa agcaaaatac ttacatagct     2100

ttcttaaaat ataggaatga cattacattt ttaggagaaa gtaagttgct ttgcaccgcc     2160

tacttaattc ttttccatat attgtgatac aaacttttga atatggaatc ttactatttg     2220

aatagaaatg tgtatgtata atatacatac atacataagc atatatgtgt gtgtgtgtgt     2280

gtatatatat atatatgcat gctgtgaaac ttgactacac aacataaatc actttttaaa     2340

ttccaggaac gggtagtctg acacggtgat tatccttttg aggctgaatc cgttattaac     2400

ttgttattta ggtttttact cccagtagca agggattcta agttagttgc acttacatga     2460

ttattgttat ttaaaactaa gaataaaggc tgcattttca aagataaatt ggaattgctg     2520

ttggtgaaat aacaaccaaa atactgaatc tgatgtacat acaggtttct acaggaagag     2580

atggtataat ttacaatttg gagatttaat aaccagggct acccagaaaa agtgacttga     2640

taacatggta ccaataagta agggatgctc tctcggtttg cttttgccac tttcaagatt     2700

ttaacttctc aggttattaa tcaaaattat tgtataagtt agccaataga atttttaggt     2760

taaaacaaca gatggggggt ttgtggagtg tttaatgtca tgggcatttt tagtagcata     2820

gaccctttgt tctgcatttg aatgtttcgt atatttttgt ttcacagtta atcttccctc     2880

cccaagtttg ctattcaaat caactgcctg aatgacattt ctagtagtct gatgtatttt     2940

tctgaggaat agtttgtgat tccaatgcag gtgtcttcat taccattacc tctacactgc     3000

agaagaagca aaactccttt attagaatta ctgcacatgt gtatggggaa aatagttctg     3060

aaaggctaga atgatacaag tgagcaaaag ttggtcagct tggctatgga gtggtggcaa     3120

taatctctaa acattccaaa agaccatgag ctgaacctaa actcccttgg aatctgaaca     3180

aaggaatata aaattgccat ttgaaaactg accagctaat ctggacctca gagatagatc     3240

agccagtggc ccaaagccat ttcaagtaca gaaattatag agactacagc taaataaatt     3300

tgaacattaa atataatttt accacttttt gtctttataa gcatatttgt aaactcagaa     3360

ctgagcagaa gtgactttac tttctcaagt ttgatactga gttgactgtt cccttatccc     3420

tcacccttcc ccttcccttt cctaaggcaa tagtgcacaa cttaggttat ttttgcttcc     3480

gaatttgaat gaaaaactta atgccatgga tttttttctt ttgcaagaca cctgtttatc     3540

atcttgttta aatgtaaatg tccccttatg cttttgaaat aaatttcctt ttgtaatttt     3600

gaaaaaaaaa aaaaa                                                      3615


<210>  2160
<211>  3844
<212>  DNA
<213>  homo sapiens

<400>  2160
gtctttacgt agacgtcggg ggcgcagccg cgctgtgcgc ggtgactggc ggctgcactg       60

gcggcagctg gaggtgtaat agtgcgggta gtgggtttgg agaagttccg aggcggcggt      120

ggcgccggtc aggacaagga tagcggaacc gggccctggg cttgtcgctc accatgccga      180

cagtagagga gctttaccgc aattatggca tcctggccga tgccacggag caagtgggcc      240

agactcatcc atctccccca actcaaaaat gaaacaaaga tggagggaga acggaattgg      300

gaagcataaa gatgcctatc aagtgatatt ggatggtgtg aaaggtggta ctaaggaaaa      360

gcgattagca gctcaattta ttccgaaatt ctttaagcat tttccagaat tggctgattc      420

tgctatcaat gcacagttag acctctgtga ggatgaagat gtatctattc gacgtcaagc      480

aattaaagaa ctgcctcaat ttgccactgg agaaaatctt cctcgagtgg cagatatact      540

aacgcaactt ttgcagacag atgactctgc agaatttaac ctagtgaaca atgccctatt      600

aagtatattt aaaatggatg caaaagggac tttaggtggg ttgttcagcc aaatacttca      660

aggagaggac attgttagag aacgagcaat taaattcctt tctacaaaac ttaagacttt      720

accagatgaa gtcttaacaa aggaagtgga agagcttata ctaactgaat ccaaaaaggt      780

cctagaagat gtgactggtg aagaatttgt tctatttatg aagatactgt ctgggttaaa      840

aagcttacag acagtgagtg gaagacagca acttgtagag ttggtggctg aacaggccga      900

cctagaacag accttcaatc cctcggatcc tgactgtgtg gacaggctct tacagtgcac      960

tcggcaggca gtacccctct tctctaaaaa tgtccattcc acaaggtttg tgacatattt     1020

ctgtgagcag gttctcccta acctcggtac cttgactacc ccagtggaag gtcttgatat     1080

acagttggag gtattgaaat tgttggcgga gatgagttca ttttgtggtg acatggaaaa     1140

actagaaaca aatttaagga aactatttga taagttattg gaatacatgc ccctccctcc     1200

agaagaggca gaaaatggag agaatgctgg taatgaagaa cccaagctac agttcagtta     1260

tgtggaatgt ttgttgtaca gttttcacca gttgggccga aaacttccag atttcttaac     1320

agccaaactg aatgcagaaa agctcaaaga tttcaaaatc aggctgcagt actttgcacg     1380

gggcctgcaa gtttatatca gacaacttcg cttagctctc cagggtaaaa cgggtgaggc     1440

cttaaaaaca gaagagaaca agattaaagt cgttgcattg aaaataacaa acaatatcaa     1500

tgttttaatc aaggatctct tccacattcc tccttcttat aagagcacag taacactatc     1560

ctggaaacct gtacaaaagg ttgagattgg gcaaaagaga gccagtgaag atacaacttc     1620

aggttcacca cccaagaaat cttcagcagg accaaaaaga gatgccaggc agatttataa     1680

ccctcccagt gggaaatata gcagcaattt gggcaacttt aattatgagc agagaggagc     1740

cttcagggga agtagaggtg gccgaggttg gggcacacga ggaaatcgta gtcggggaag     1800

actctactga ataagacatc agcattcttc agcattgtca tgagcttaat atacttaaat     1860

tctactactc attggattgc cggggatgtc cctttaaaca gactgctgcc ttcagctaaa     1920

aacttaatgt tctttatacc tttgtatgta tgacctactt ttgtaacaga ccatggttgt     1980

gtccaaggta aaaccacagt gatatttttg gatgctttgt ctgcaatctt gacttgtttt     2040

tgcagtatca ttattcagac ttcaaattgt gaatctttta aacatcttga taatttgttg     2100

ttgagagctg ttcattctaa aatgtaatga aattcagtct agttctgctg ataaagatca     2160

tcagttttga aaggttactg attttcctct tccctcttag ttttttaccc aatatatgga     2220

gaagagtaat ggtcaatctt aacattttgt tttaattgtt taataaagct gctgggcagt     2280

ggtgcagcat tcctacctag tgtcataaaa gcaaaatact tacatagctt tcttaaaata     2340

taggaatgac attacatttt taggagaaag taagttgctt tgcaccgcct acttaattct     2400

tttccatata ttgtgataca aacttttgaa tatggaatct tactatttga atagaaatgt     2460

gtatgtataa tatacataca tacataagca tatatgtgtg tgtgtgtgtg tatatatata     2520

tatatgcatg ctgtgaaact tgactacaca acataaatca ctttttaaat tccaggaacg     2580

ggtagtctga cacggtgatt atccttttga ggctgaatcc gttattaact tgttatttag     2640

gtttttactc ccagtagcaa gggattctaa gttagttgca cttacatgat tattgttatt     2700

taaaactaag aataaaggct gcattttcaa agataaattg gaattgctgt tggtgaaata     2760

acaaccaaaa tactgaatct gatgtacata caggtttcta caggaagaga tggtataatt     2820

tacaatttgg agatttaata accagggcta cccagaaaaa gtgacttgat aacatggtac     2880

caataagtaa gggatgctct ctcggtttgc ttttgccact ttcaagattt taacttctca     2940

ggttattaat caaaattatt gtataagtta gccaatagaa tttttaggtt aaaacaacag     3000

atggggggtt tgtggagtgt ttaatgtcat gggcattttt agtagcatag accctttgtt     3060

ctgcatttga atgtttcgta tatttttgtt tcacagttaa tcttccctcc ccaagtttgc     3120

tattcaaatc aactgcctga atgacatttc tagtagtctg atgtattttt ctgaggaata     3180

gtttgtgatt ccaatgcagg tgtcttcatt accattacct ctacactgca gaagaagcaa     3240

aactccttta ttagaattac tgcacatgtg tatggggaaa atagttctga aaggctagaa     3300

tgatacaagt gagcaaaagt tggtcagctt ggctatggag tggtggcaat aatctctaaa     3360

cattccaaaa gaccatgagc tgaacctaaa ctcccttgga atctgaacaa aggaatataa     3420

aattgccatt tgaaaactga ccagctaatc tggacctcag agatagatca gccagtggcc     3480

caaagccatt tcaagtacag aaattataga gactacagct aaataaattt gaacattaaa     3540

tataatttta ccactttttg tctttataag catatttgta aactcagaac tgagcagaag     3600

tgactttact ttctcaagtt tgatactgag ttgactgttc ccttatccct cacccttccc     3660

cttccctttc ctaaggcaat agtgcacaac ttaggttatt tttgcttccg aatttgaatg     3720

aaaaacttaa tgccatggat ttttttcttt tgcaagacac ctgtttatca tcttgtttaa     3780

atgtaaatgt ccccttatgc ttttgaaata aatttccttt tgtaattttg aaaaaaaaaa     3840

aaaa                                                                  3844


<210>  2161
<211>  3908
<212>  DNA
<213>  homo sapiens

<400>  2161
atcccagtgg gtggcagctg gaggcggggc accctgaggg gcggggaagg actagggtgc       60

ggggaggggg ttgcaaaagg agccgagcgg cttctgctca atggcggaaa agccgccggt      120

gctctgacgg cctcgttccc ctagcagttg cgggggagtt tcctgccggc gcggctggag      180

tctctgattc tcagggttcg gtggttggaa gatgctccag agagacgagg ctgcggcgga      240

ggaggtggcg gcggccgaat cggcaacggc gctagggtgg agagaaggcg gcatcggcgg      300

cggcggcggc gtgaggggcc gggcggtgta aacagccccg gaggcggcgg tcgagacccc      360

gagggggaag cggcggctga gtcagggtcg cgcctccgtt ggaaacttgg gctgagtacc      420

gcggcgggcg cgagcgaggc gccctagaca tcttctccct cccttgcctc agatttattg      480

ctaaacatgg gtgcattttt ggataaaccc aaaactgaaa aacataatgc tcatggtgct      540

gggaatggtt tacgttatgg cctgagcagc atgcaaggat ggagagtgga aatggaagat      600

gcacacacag ctgttgtagg tattcctcac ggcttggaag actggtcatt ttttgcagtt      660

tatgatggtc atgctggatc ccgagtggca aattactgct caacacattt attagaacac      720

atcactacta acgaagactt tagggcagct ggaaaatcag gatctgctct tgagctttca      780

gtggaaaatg ttaagaatgg tatcagaact ggatttttga aaattgatga atacatgcgt      840

aacttttcag acctcagaaa cgggatggac aggagtggtt caactgcagt gggagttatg      900

atttcaccta agcatatcta ctttatcaac tgtggtgatt cacgtgctgt tctgtatagg      960

aatggacaag tctgcttttc tacccaggat cacaaacctt gcaatccaag ggaaaaggag     1020

cgaatccaaa atgcaggagg cagcgtgatg atacaacgtg ttaatggttc attagcagta     1080

tctcgtgctc tgggggacta tgattacaag tgtgttgatg gcaagggccc aacagaacaa     1140

cttgtttctc cagagcctga ggtttatgaa attttaagag cagaagagga tgaatttatc     1200

atcttggctt gtgatgggat ctgggatgtt atgagtaatg aggagctctg tgaatatgtt     1260

aaatctaggc ttgaggtatc tgatgacctg gaaaatgtgt gcaattgggt agtggacact     1320

tgtttacaca agggaagtcg agataacatg agtattgtac tagtttgctt ttcaaatgct     1380

cccaaggtct cagatgaagc ggtgaaaaaa gattcagagt tggataagca cttggaatca     1440

cgggttgaag agattatgga gaagtctggc gaggaaggaa tgcctgatct tgcccatgtc     1500

atgcgcatct tgtctgcaga aaatatccca aatttgcctc ctgggggagg tcttgctggc     1560

aagcgtaatg ttattgaagc tgtttatagt agactgaatc cacatagaga aagtgatggg     1620

ggtgctggag atctagaaga cccatggtag ccttaaaaac cttctaaaat gcttttgatt     1680

ctgaaaattg ggggaaaaaa cttttaatca caattttctt caatacaagg ggaaaatatt     1740

cttgcggatt cccaacgttt tgtgatatga gcagaaaatc attagcattt cccatcattt     1800

gttcatattt gtgttttctg acagttgcca cttgtagcat tgcctgtact acagtatttt     1860

ttgccaacct caggcatact cgttacatct gtattgaact ttcggcccta gaaaccagtg     1920

gagttatttc accacaaatc aacaatgtgc ctgaggtgca tgggaaatat agttagctat     1980

actctgaaaa tacattatgt tttttttctt taaacaaaac acacaacatg taagcatgta     2040

agagtaaaga attgtatgat atgttccttt tttcagttca ccaagttgga agccttttgc     2100

agctctgtgg cttggaattt catttgagca atttctatag gatatgtatt tattattgat     2160

tgttatttaa tttttttcca attttacctg tattaccaaa ctgggttctc caataatgtc     2220

caaattgtaa tgttgccttg cttcaagata aagtgtattt gggaataata ttataaaccc     2280

ttacaaattt tatgcatgta tctactgcat ccttcaactc tcactagaaa atcttttgaa     2340

accaaatgga ttaatttatg gctatttata atttgctttg acatctcact gttggaaatt     2400

ttttaaagat gagatttgcc tttataatgt aaattgtgat ttttgtttta catgtgggtt     2460

tctatagttt taattttttc agcttttaag atacgagttt tgtgtaattt ggtattttta     2520

atcatttatg ttattttaaa agctcagaat atcacattga aattactata aatacattta     2580

aaattatcta ttttagatct aaggaaatac tacagagata ttttcatggg ttcagtaact     2640

tttcatttta taacattggg cacggtacag agtgattgtc acataaggta cttgaagatt     2700

tattagttta attctatttt tacagtaacc ttgaattctt ctgagttttg catgtattaa     2760

attcaattaa tgctgaacat gaagagtaaa gtatttatct gaaagaagtt tctgggttag     2820

gagaagtaat gaatgtatcc atttgtacat ggtttacatg ttgtggatgc tttgtaaaca     2880

ttttcctgta tgtttaaatt gtgtttcagc aggatgtaat tgcccttgtg tgtagttaaa     2940

atgagtcatc atctggtcct ttgtgaaatg gaattcatgg tattttctgt aacgttttcc     3000

tgaagctgtt tctggagagc cacacattta aatacagaca gctttcctga tcatttgatt     3060

tattgtgcac ctgatttttg gtctaaaagg aattattgcc acaatatatt ttatttattc     3120

tttagatttt agccttgtaa gttaaagtgc tttacatgat gatgtgaaaa gctgtttgtc     3180

cctttactgg gtttgggggg ttgttaaaag atagggaatg aagaatgcaa aatggtttat     3240

cgttcaaact gtccactctg atccaaccct gtactgatag tacttcccag tatgatattg     3300

tgatgtttca tacaatgcag tgaacataac caacttgtta cctaaataaa gaattgataa     3360

aaacagtgtg acatattact atttggtatg attcagtttt taatgttatt ttaaacttct     3420

tatatggttg gcatatttct gaaaatttaa ttccaaagag gaattaacca aactgtacag     3480

gacaatatta accccttctg tactctagaa atatttatac tccttttaaa aaaacctgcc     3540

tttggccggg tgcattggct cacacctgta atcccagcac tttgggaggc caaggcgggt     3600

ggatcacgag gtcaagagat cgtgaccatc ctggccaaca cggtgaaacc ctgcctctac     3660

taaaaataca aagattagct gggcatggtg gtgcttgcct gtaatcccag ctgcttggga     3720

ggctgaggca gaagaattgc ttgaacccag gaggcggagg ttgcagtgag ctaagatcgc     3780

gccactgcac tccagcctgg cgacagagcg agactccgtc tcaaaaaaaa aaaaaaagaa     3840

aaaaaaaaac ttttccggca gggggcaggg tgggggttac tggtgcttga aacagaaata     3900

atgtatga                                                              3908


<210>  2162
<211>  1829
<212>  DNA
<213>  homo sapiens

<400>  2162
atcccagtgg gtggcagctg gaggcggggc accctgaggg gcggggaagg actagggtgc       60

ggggaggggg ttgcaaaagg agccgagcgg cttctgctca atggcggaaa agccgccggt      120

gctctgacgg cctcgttccc ctagcagttg cgggggagtt tcctgccggc gcggctggag      180

tctctgattc tcagggttcg gtggttggaa gatgctccag agagacgagg ctgcggcgga      240

ggaggtggcg gcggccgaat cggcaacggc gctagggtgg agagaaggcg gcatcggcgg      300

cggcggcggc gtgaggggcc gggcggtgta aacagccccg gaggcggcgg tcgagacccc      360

gagggggaag cggcggctga gtcagggtcg cgcctccgtt ggaaacttgg gctgagtacc      420

gcggcgggcg cgagcgaggc gccctagaca tcttctccct cccttgcctc agggaagtcg      480

agataacatg agtattgtac tagtttgctt ttcaaatgct cccaaggtct cagatgaagc      540

ggtgaaaaaa gattcagagt tggataagca cttggaatca cgggttgaag agattatgga      600

gaagtctggc gaggaaggaa tgcctgatct tgcccatgtc atgcgcatct tgtctgcaga      660

aaatatccca aatttgcctc ctgggggagg tcttgctggc aagcgtaatg ttattgaagc      720

tgtttatagt agactgaatc cacatagaga aagtgatggg gcctccgatg aagcagagga      780

aagtggatca cagggaaaat tggtggaagc tctcaggcaa atgagaatta atcatagggg      840

aaactaccga caacttctgg aggagatgct gactagttac aggctagcta aagtagaggg      900

agaagaaagc cctgctgaac cagctgccac agctacttct tcgaacagtg atgctggaaa      960

cccagtgaca atgcaggaaa gccatactga atcagaaagt ggtcttgctg aattagacag     1020

ctctaatgaa gatgcaggga caaagatgag tggtgaaaaa atatgacttt cctttttggt     1080

aatatttttg tgatctttga tggtttttaa cctaggaagt gtaatgtatg catttatata     1140

actgttttgt tatttgaatc ttggaaaact agttttatta tattcagata gccttgtttt     1200

ttaaaaaggc ctttgcatac acctttatga gatagtgtaa aattgactat ttatagtact     1260

atggatttaa tgaaattata tgtcatttca cattgtatgc cagaaattag gctaccaatt     1320

atgaattaaa gtcagtagtt aaattaatac tagatagaat tagaaatttt gattagagag     1380

attatgctat attatggaaa aacttgttaa tgtagaatta tactgcttca tattatttta     1440

cctattagta cactcatagt tagctttgta ataaatttat gttttcttta ataattttag     1500

ttcttcaaag aatggctgat gctggcctgt aatttttctt tcaaggatga taatttgtgt     1560

gttgtttgat ttgtttatat tttacatctc tgtagtttta tttttagaag ttgtgagata     1620

ttggatgtgt ggctattttt cctttctctg tattctttat gaaacataac ttttgaaaaa     1680

cctatgtatt attcatacag ctttggtttg tatattctgt atagcctaac tacacacatc     1740

aaaatgtatg tcaaccaagt gtttagaatg aaattataag tgtttaagtc caaataaagc     1800

atgtgatgtg gaataatcta taaaaaaaa                                       1829


<210>  2163
<211>  9487
<212>  DNA
<213>  homo sapiens

<400>  2163
gtgcttcgta gagctgccgc cgtcgccgct gccgctgccg ccacagccgc cgctgcagcc       60

ggagcatccg ggagccgcca ctgccgccgc cgctgccgct gctaccgcca ctagcgctgc      120

ttccactgct tctacctccc ctcccaggac cccgagacac cccgggcgcg agcggcagtg      180

ctgcttgctt gctcctcctc tcccccagcc cttcccctcc gtgacctacc cactccttgc      240

agccctcgcc cgcaccttct ccaacacccc ggcatccctg caccacctgc tcgggcagcc      300

ccggcgggct ctgggacttg ctgtgcgcgc cgagaggaag gcaagctcca aacccctgcc      360

tggaagacgg gctgtcgcgg ctgcaccacc agcaggagga ggaggagaag aaactatttc      420

gcgatacccc attctgcggg tgctttgccg ctgccgcttc tgctgccgcc gatccgagtc      480

cgcgggttcg aacaccgcag cggtggggac ggtgggtccg gcgggcgccg ggaggaggac      540

accagcggag ccctgcactc tcgtgccccg ctcaccagca tctacttgcc ccctcgttcc      600

ttccccagcc ctttagagaa gggaccatga tttggaaacg cagcgccgtt ctccgcttct      660

acagtgtctg cgggctcctg ctacaagcgg ctgcttcaaa gaataaagtt aaaggcagcc      720

aagggcagtt tccactaaca cagaatgtaa ccgttgttga aggtggaact gcaattttga      780

cctgcagggt tgatcaaaat gataacacct ccctccagtg gtcaaatcca gctcaacaga      840

ctctgtactt tgacgacaag aaagctttaa gggacaatag gatcgagctg gttcgcgctt      900

cctggcatga attgagtatt agtgtcagtg atgtgtctct ctctgatgaa ggacagtaca      960

cctgttcttt atttacaatg cctgtcaaaa cttccaaggc atatctcacc gttctgggtg     1020

ttcctgaaaa gcctcagatt agtggattct catcaccagt tatggagggt gacttgatgc     1080

agctgacttg caaaacatct ggtagtaaac ctgcagctga tataagatgg ttcaaaaatg     1140

acaaagagat taaagatgta aaatatttaa aagaagagga tgcaaatcgc aagacattca     1200

ctgtcagcag cacactggac ttccgagtgg accggagtga tgatggagtg gcggtcatct     1260

gcagagtaga tcacgaatcc ctcaatgcca cccctcaggt agccatgcag gtgctagaaa     1320

tacactatac accatcagtt aagattatac catcgactcc ttttccacaa gaaggacagc     1380

ctttaatttt gacttgtgaa tccaaaggaa aaccactgcc agaacctgtt ttgtggacaa     1440

aggatggcgg agaattacca gatcctgacc gaatggttgt gagtggtagg gagctaaaca     1500

ttcttttcct gaacaaaacg gataatggta catatcgatg tgaagccaca aacaccattg     1560

gccaaagcag tgcggaatat gttctcattg tgcatgatcc taatgctttg gctggccaga     1620

atggccctga ccatgctctc ataggaggaa tagtggctgt agttgtattt gtcacgctgt     1680

gttctatctt tctgcttggt cgatatctgg caaggcataa aggaacgtat ttaacaaatg     1740

aagctaaagg agctgaagat gcaccagatg ctgatacagc cattatcaat gctgaaggca     1800

gccaagtcaa tgctgaagag aaaaaagagt atttcattta agatgcaggc caagattctg     1860

agttttacta ccaggctgaa tgctggagaa aactggctat catctttcag aagtcatttc     1920

taccatcgtc tgctaccctt attaactccc atactgtact gctatcagta gccagtgtat     1980

accaacaatc agctgttgaa agcatcattc tttaattact gtaccatcca taatgcagga     2040

catttcttac tgcctaaatt tcacaccatt gctcttttaa catacagtgc ttgaatatac     2100

agccttaaca atgttaatca tctccttgga tcattatatt gagtggtttt tatacattaa     2160

aaaatgtatg cagagttttt ttcccccatt ttttcccctt taagtcatag accttatcag     2220

tttgccattg gacagctttc acaagtaaca ggattaggga aggacataat gtatttaaga     2280

ataagtgaag gttagaggtt tacaattaat gttttctaca tgtctgtctt caaagacaac     2340

atgctttgga aacatatgtc ctagaaaaca taaaattaaa aaaaaacact atagtgtagt     2400

ttttggaatg ttggagatta tactggtaaa gctgtatcga tttgctattg aaatatagta     2460

tttgatacag gagccatgtg tacgaattgc aatcatgaca tggtattttc tataattata     2520

gagatcttac tattaggata ttgtagcttc atttaccaat aaattattcc aaatgattta     2580

ctgcttttgg aatcacaaat atttaattca tttctctaat ttgattctat aatttatttg     2640

cttcataaag attcacctgc ctaaacaata ttgaagtatc catagggcac aattttcaga     2700

cattttagta tctgtatata gtgcatataa taaatccaat taaacattat ttgatacata     2760

tttaactttt ttggctgtat gtaattcagt cataagtaag cattttctaa cgtccattat     2820

atccctttag gtattactta aaccaatatt ataagtagat aacatgtatt agtatttttg     2880

tctgtatgtc ctagcactgt tcaacaacaa atttttctag ttcttgttaa tttttatttg     2940

ttatacaatg gaagcacaat gttataagga aaggtaattt taagctaaca accagtgcac     3000

agcctcaggt tttaaattac aaccacagtt gaataataac ctaaaaataa attttagttt     3060

gctaaaaatt tacaaatttt cattttgcag ttccagagct gcttacctat gttggtttgc     3120

caaaaagaag tgtttaagat atgttttctg tataaatgaa ctaattcttt atattaaatt     3180

cctgtctatg cattttgtga ggtacaaact gatgaaacag tgagtgatag agaatttctg     3240

ccatgctttt aactccaaag tgaaagtctc tttctctgga ttattttaaa attttggcgt     3300

gtttaaccat taagaaatgc tgtattctta aatatgaaac agttaatcta aagtcttatt     3360

atttcttcta gtaaaataaa atattgttag attagttctc attaaattta ttatatgcta     3420

aagaataaaa ctccagttag atttaaaaaa atcccattta caagcattgc acctttaaga     3480

agaaaacaaa tatgacagta tggtagctat acttgtgatg tctgacgcat gatggcctat     3540

ggttttaaaa atagtattgt ggaatatatt tttgggtaat aagaatggtt gagtgcaaca     3600

tcatgtatta atatcaaatg aaagacaagg gtgctgtatc tttgattatt tatcaaaaaa     3660

gtataaatct tttaaggaaa atgttagaat tttaaagttt ttttttgatt gttgaagcat     3720

ttatcttgtt gatttcttac aaaagaaaaa ggacgatgtc agtcaagcag cactttttca     3780

gaatatacag aacataaata atatgatgtg gttgagtgtt aacataataa atcatataca     3840

gtatgacatt ttaaggaaat aagtctgcat tgatgtgatt gcatgcttgt ttttacagtt     3900

cactccatac catctgtgga aaaatgcaat aatatgttaa tatagtatgg tagtttgaga     3960

gaatcaggta ggtgctacta gacacattga aactagaata ggtttataaa ctgttcatat     4020

ctttcaatgc ataatcttta gaaagactcc acaaagcaaa attcatcctg ttagtacaaa     4080

atggaaaggt tcttattaca gaagtaagtt gtacaaactg catcatcaat tactatgtaa     4140

agcctaattt caggatgcac ttacaaaatt gctactcttc atcgatgccg tatttacatc     4200

cctcttcatt tcatctatat tctacttggc tccaacaact aaattgttgc ctaaataact     4260

caatcattat ttatagcact gtaaaattag aaatccaaaa ttggttgcat ttcatgattt     4320

ttgactcttt taacccttca gagtaatata aaatctcatt agaactctta taaaaccagt     4380

tagctaaaac aactagatta ttatactagt tataaatgct ggtatattat aatttgtggg     4440

atctaattaa atgtttgcct attaaatata gtttgattta aatgagacac catgttctga     4500

actggagaaa acaatatcaa tgaagtcata ttttcatacc tttaaaaatt atttaatttt     4560

caaccaaaca aaaaataaat tgtaaaaatt atgctcattt ctattccaac aagtcagaaa     4620

ataatgacat aatatttcta aatgagaatg atgtcaattt cattgtctgg aacatgcaca     4680

cttgtgtgca catagagtca atttctgtct cttctaagtg agcacagtag gtagggaact     4740

caatggaagc agtgtgcaca cacacacacc cttagtagaa tatggagcat tattctttac     4800

caaaagtagc tattctctgc cagtgtactg tttacagtgt aaattgattg tcctccgtca     4860

aaatcaagtc taagcggcat tttacttttc ttttcttttt tattttccat ttttgggtgt     4920

tctagatagg attattatca aaagtaggag gaaaaagaaa tgtttgtgag tgcaagatta     4980

aagacagagc gcatgagcag agtactgatg gtgtgcgtgt ttgtgtgtgt gtatatgtgt     5040

gtgtataaga gagaaagaga aatcgaaaag agagagaaat ttcaacttgt tttcttttac     5100

cagagaatcc aagaagcagt ttaaggaacc tgatattgga gtttaatcta gaaactggat     5160

gatctcatat tgattcatga tgcttaatct ttcattgaaa ctccacaatt aaaataacaa     5220

atagagaaag aaaactaact ttcctaaata tggcaaagaa actaacacct catttatttt     5280

tatttctttg taaaaatata aatatctcaa tcaaaagtac aggctcattt gtaattatgt     5340

actcatgatt gtaacagcat tgagatttca tataggcaca tgtatagcag ctgtttgaca     5400

gtgatggctc ttccatgtaa catagcagtt atcgtgtaat ttagtgccac ttattgcaaa     5460

gtgttaccaa ggggaacatt tcaaatgcct tttgtttttc tttggacatc aaggtaattt     5520

agtggacaac aaatattaaa ttttacatta tgctttttaa ttgtggagaa aatgcaaaac     5580

ctcatgtctt accacaactt tcccatggta ttgctaatta cttagagtct ctaaaattgc     5640

ccaatattat ttccctttgc aaatggtaat ttctgataaa acaatacaaa acaaaaaaaa     5700

agcagtaatc acagccaaat aaatgaaaca cctaatgaga attactgttg agtaatgctt     5760

tttattaagt ggcacaaagt acacactaaa aactatgcaa aatataggta actacagtgt     5820

acgtacatgt aagtatcttg tacttgctgt gtatggatgt tggaaaccca tgtaattata     5880

atatgcattt tgaatattgg gaaagaggaa atcttagtgt agataataga atttgttttg     5940

aaatatacac tggcaatatt gaaatatact cagtgcaata tctgcagttc tattgctgga     6000

tacttaatgc aaagggattt taaagaattc ttcagcaaga tccaagaggt tgctaatctt     6060

cacctctcac atactaaagc attcattaaa aatacaacta attcaaggac aagttaagtt     6120

tttcttatta atgtgacaca gtaacatttt tatttggatt agtttttggt gttattgcag     6180

agaaagaaat aacctgagtt ttaaatttcg attcatatct cattgaattg ggaattcttc     6240

aattttgttt gaaatgtgtg catgttttca tagattgtag caagtacaaa tgtattcaat     6300

gaaagaacat agggtagttt taatagttaa agtcactata tcttaatggg aattttaaaa     6360

tatcttttct ttttctattc attttttccc tttctctctc tattctaccc ccaaacaagc     6420

cctttgcact catacccttc caaaggcaat ggattgaaag tagcaagata ataaagagag     6480

ttaaagggga caacatataa caatgggttc taaaatcatc agcattttta tgtattgaga     6540

ttattaatat tgaatgcaat agttattgga tatagctggt aagttctctg ccatgcatac     6600

ttacaataat ccttctacct ctcactttta acatgggcta tgatacttca atataaatag     6660

aggaaataat tatttaccag atatcccagg aagcattctt atggaactat tataacagtg     6720

cactccccac cccctgggaa atctcaaaag ccaagttctt cagtgtattc tatggtgtat     6780

gaatctgcat ttgtttttcc ttttctatca ttagcttttc ctaaaggcaa aatattataa     6840

ctttataaga atagtccttc tcctgcctat ttaatatttc aatgttaata taattgtatt     6900

ggtttttaaa aataattaaa atggcaacac tttgcgatcc aatctgatat ttaattttta     6960

aaatgtaaca atttcttata aattcatgct gtgttttaag taaaaatcat gtatatgaat     7020

tattttacca agtagtatta tctgcacgag acaaatttaa gtattttaaa aatcatcctt     7080

attaataaat aatcctcata taatgcacag tattgccaca aatgcccact tcattttgtc     7140

tgcatagaca tattaagaat ttttcaatga tgtaatttaa ttatcctaaa agaaatgaca     7200

gattcttctg taggaaaaaa taaaaacatg aatatctcaa attataatgg ttaatctcta     7260

aaatatgctt aaagtaagat gtttctatgt tatgtggtta tgttatcaat aatatttggt     7320

tgatcttcac atattttata tgcatatata tatcaagaag ttatatatat ataactcaag     7380

aaactcaagt tatatatata tgtcaagaaa tgtatgatta ttttggagag aatgggccca     7440

aatgtgaaaa agatataaaa aaaacaaaaa aaacaaaaaa aaaacactat tttcccctac     7500

gaaatatact gtatatttca aaagaagaaa agttaaaaga tatttgaaga ttgcaggggc     7560

aaaacaaaaa cctaccaggg ctcagcactt aagcactttt cccacatcca gggtcaaagc     7620

agcagtaact acatggactt ttaagtgcgg tatgaaatgc aacattacgc ttacaaacag     7680

tactgtcaaa cctcaaatgc tttctttctt cagatgcttt ttcgtgtaca tgatactagt     7740

agacactttt ctctttatat ttactgatag tgaaaatcat acgcaataaa atattgatgt     7800

ttgaaggcag tggtcaccaa ttggttaaaa aactatgaaa tgtaaactga attgttatat     7860

ctctatcctt tttgcttttc tctgtgtttt taatgtatgg aataaatctc ataaatagaa     7920

agaaaaataa tctagaaatt tttcaaagct agtactcttt ctccttataa atgtacacaa     7980

ttttaatctt tttacaaatt tatttaactg tacctactgt acttattgta gattcaatga     8040

cgcagttaag tcatcaccca aggatttatg aatttgagat tactgacctg ttttcttcat     8100

attgcattca catcaatatt tgtgaatttg ttgttcagct tttcattcaa acaaaaaata     8160

ttccctcaag aaagctccat ttttatcata aacatttcaa cataaccaac attagaacaa     8220

gtctgccatg ttaaaaataa tttaaagact tatctctgaa aacggtatcc agaaacgcag     8280

gtgttcccag taatgtagct tcaaaaataa aatgtgctat ttatatgaca tgaaattcat     8340

aacttttgga agggtatatt tatgacagca taaaaaataa attctgtgct ataaagaaga     8400

tccaacaaat taaccatata agcacagaaa atagagaaac acagttattg aatctactct     8460

tgtcattaac attttcaaaa aacaaaatgc atattgtaat atttggtaca tgacacttgc     8520

atgttgatat gcctatatac ttacaaagta ttcaatgtgt acttagcggc gcttaaaata     8580

tgtcatgtac aactcttata aacattttta cagggttccc atttgcactt catctttcag     8640

taaagtcttg tcagaaaaaa attgtctgat aaatatggaa aaataaaatt tgaattttag     8700

ttatctgttg gacattactg aattgtctat tcatttagta cattttctta accttgaaaa     8760

cagacattga aagatggaac tttctttttt ccagtgacag gtcattaaat cgatggtaca     8820

aaacatactt ctttatgcca aacacattat tttgaatacc tttttttcaa cttcatacat     8880

tatccatcca ttttagtttt cctcgatgat gcccattttc tttgtaaatt tctaagtgga     8940

agttttaaaa attaagcatc agtaaaataa atgttatctt atttgtacaa catttaatcg     9000

ttattccttg gaatatatga accttgtaaa gtgatgacta agggtcaaaa aaaatgttgc     9060

tgacttaggg aaatttgctt gagaatgcca aaattttaaa actctgtaaa ggtaatttta     9120

cattcactta tgtgtgttta ctaatgttga gtaggaacag aagcaaaaat acctaaacct     9180

atttttttta accttcacac tctaaccagt attatatatt tcagctacct aagataatgc     9240

aattaatcat atatccaacc taagcttctg ccaataagga tttcagataa gcttttaaat     9300

ttatggagga ttttctttgt gtctttggaa gttcacttac cataaagtat tttatagtct     9360

actttaaata acagattttg ttacacaggg taagccaaag gctgtacaag atttagtgtc     9420

attgggtctc atatttgtgt tagaccatga aatattccat taaaatttat ctgtaaatac     9480

aaggcaa                                                               9487


<210>  2164
<211>  8960
<212>  DNA
<213>  homo sapiens

<400>  2164
atgtttgttc tcttcttgtg caacctttcc ttggtaccag cggctgcttc aaagaataaa       60

gttaaaggca gccaagggca gtttccacta acacagaatg taaccgttgt tgaaggtgga      120

actgcaattt tgacctgcag ggttgatcaa aatgataaca cctccctcca gtggtcaaat      180

ccagctcaac agactctgta ctttgacgac aagaaagctt taagggacaa taggatcgag      240

ctggttcgcg cttcctggca tgaattgagt attagtgtca gtgatgtgtc tctctctgat      300

gaaggacagt acacctgttc tttatttaca atgcctgtca aaacttccaa ggcatatctc      360

accgttctgg gtgttcctga aaagcctcag attagtggat tctcatcacc agttatggag      420

ggtgacttga tgcagctgac ttgcaaaaca tctggtagta aacctgcagc tgatataaga      480

tggttcaaaa atgacaaaga gattaaagat gtaaaatatt taaaagaaga ggatgcaaat      540

cgcaagacat tcactgtcag cagcacactg gacttccgag tggaccggag tgatgatgga      600

gtggcggtca tctgcagagt agatcacgaa tccctcaatg ccacccctca ggtagccatg      660

caggtgctag aaatacacta tacaccatca gttaagatta taccatcgac tccttttcca      720

caagaaggac agcctttaat tttgacttgt gaatccaaag gaaaaccact gccagaacct      780

gttttgtgga caaaggatgg cggagaatta ccagatcctg accgaatggt tgtgagtggt      840

agggagctaa acattctttt cctgaacaaa acggataatg gtacatatcg atgtgaagcc      900

acaaacacca ttggccaaag cagtgcggaa tatgttctca ttgtgcatga tgttcccaac      960

actttgcttc ccactactat catcccctcc cttaccactg caacagtcac aaccactgta     1020

gccataacaa ccagcccaac cacatctgca acaaccagca gcatcagaga tcctaatgct     1080

ttggctggcc agaatggccc tgaccatgct ctcataggag gaatagtggc tgtagttgta     1140

tttgtcacgc tgtgttctat ctttctgctt ggtcgatatc tggcaaggca taaaggaacg     1200

tatttaacaa atgaagctaa aggagctgaa gatgcaccag atgctgatac agccattatc     1260

aatgctgaag gcagccaagt caatgctgaa gagaaaaaag agtatttcat ttaagatgca     1320

ggccaagatt ctgagtttta ctaccaggct gaatgctgga gaaaactggc tatcatcttt     1380

cagaagtcat ttctaccatc gtctgctacc cttattaact cccatactgt actgctatca     1440

gtagccagtg tataccaaca atcagctgtt gaaagcatca ttctttaatt actgtaccat     1500

ccataatgca ggacatttct tactgcctaa atttcacacc attgctcttt taacatacag     1560

tgcttgaata tacagcctta acaatgttaa tcatctcctt ggatcattat attgagtggt     1620

ttttatacat taaaaaatgt atgcagagtt tttttccccc attttttccc ctttaagtca     1680

tagaccttat cagtttgcca ttggacagct ttcacaagta acaggattag ggaaggacat     1740

aatgtattta agaataagtg aaggttagag gtttacaatt aatgttttct acatgtctgt     1800

cttcaaagac aacatgcttt ggaaacatat gtcctagaaa acataaaatt aaaaaaaaac     1860

actatagtgt agtttttgga atgttggaga ttatactggt aaagctgtat cgatttgcta     1920

ttgaaatata gtatttgata caggagccat gtgtacgaat tgcaatcatg acatggtatt     1980

ttctataatt atagagatct tactattagg atattgtagc ttcatttacc aataaattat     2040

tccaaatgat ttactgcttt tggaatcaca aatatttaat tcatttctct aatttgattc     2100

tataatttat ttgcttcata aagattcacc tgcctaaaca atattgaagt atccataggg     2160

cacaattttc agacatttta gtatctgtat atagtgcata taataaatcc aattaaacat     2220

tatttgatac atatttaact tttttggctg tatgtaattc agtcataagt aagcattttc     2280

taacgtccat tatatccctt taggtattac ttaaaccaat attataagta gataacatgt     2340

attagtattt ttgtctgtat gtcctagcac tgttcaacaa caaatttttc tagttcttgt     2400

taatttttat ttgttataca atggaagcac aatgttataa ggaaaggtaa ttttaagcta     2460

acaaccagtg cacagcctca ggttttaaat tacaaccaca gttgaataat aacctaaaaa     2520

taaattttag tttgctaaaa atttacaaat tttcattttg cagttccaga gctgcttacc     2580

tatgttggtt tgccaaaaag aagtgtttaa gatatgtttt ctgtataaat gaactaattc     2640

tttatattaa attcctgtct atgcattttg tgaggtacaa actgatgaaa cagtgagtga     2700

tagagaattt ctgccatgct tttaactcca aagtgaaagt ctctttctct ggattatttt     2760

aaaattttgg cgtgtttaac cattaagaaa tgctgtattc ttaaatatga aacagttaat     2820

ctaaagtctt attatttctt ctagtaaaat aaaatattgt tagattagtt ctcattaaat     2880

ttattatatg ctaaagaata aaactccagt tagatttaaa aaaatcccat ttacaagcat     2940

tgcaccttta agaagaaaac aaatatgaca gtatggtagc tatacttgtg atgtctgacg     3000

catgatggcc tatggtttta aaaatagtat tgtggaatat atttttgggt aataagaatg     3060

gttgagtgca acatcatgta ttaatatcaa atgaaagaca agggtgctgt atctttgatt     3120

atttatcaaa aaagtataaa tcttttaagg aaaatgttag aattttaaag tttttttttg     3180

attgttgaag catttatctt gttgatttct tacaaaagaa aaaggacgat gtcagtcaag     3240

cagcactttt tcagaatata cagaacataa ataatatgat gtggttgagt gttaacataa     3300

taaatcatat acagtatgac attttaagga aataagtctg cattgatgtg attgcatgct     3360

tgtttttaca gttcactcca taccatctgt ggaaaaatgc aataatatgt taatatagta     3420

tggtagtttg agagaatcag gtaggtgcta ctagacacat tgaaactaga ataggtttat     3480

aaactgttca tatctttcaa tgcataatct ttagaaagac tccacaaagc aaaattcatc     3540

ctgttagtac aaaatggaaa ggttcttatt acagaagtaa gttgtacaaa ctgcatcatc     3600

aattactatg taaagcctaa tttcaggatg cacttacaaa attgctactc ttcatcgatg     3660

ccgtatttac atccctcttc atttcatcta tattctactt ggctccaaca actaaattgt     3720

tgcctaaata actcaatcat tatttatagc actgtaaaat tagaaatcca aaattggttg     3780

catttcatga tttttgactc ttttaaccct tcagagtaat ataaaatctc attagaactc     3840

ttataaaacc agttagctaa aacaactaga ttattatact agttataaat gctggtatat     3900

tataatttgt gggatctaat taaatgtttg cctattaaat atagtttgat ttaaatgaga     3960

caccatgttc tgaactggag aaaacaatat caatgaagtc atattttcat acctttaaaa     4020

attatttaat tttcaaccaa acaaaaaata aattgtaaaa attatgctca tttctattcc     4080

aacaagtcag aaaataatga cataatattt ctaaatgaga atgatgtcaa tttcattgtc     4140

tggaacatgc acacttgtgt gcacatagag tcaatttctg tctcttctaa gtgagcacag     4200

taggtaggga actcaatgga agcagtgtgc acacacacac acccttagta gaatatggag     4260

cattattctt taccaaaagt agctattctc tgccagtgta ctgtttacag tgtaaattga     4320

ttgtcctccg tcaaaatcaa gtctaagcgg cattttactt ttcttttctt ttttattttc     4380

catttttggg tgttctagat aggattatta tcaaaagtag gaggaaaaag aaatgtttgt     4440

gagtgcaaga ttaaagacag agcgcatgag cagagtactg atggtgtgcg tgtttgtgtg     4500

tgtgtatatg tgtgtgtata agagagaaag agaaatcgaa aagagagaga aatttcaact     4560

tgttttcttt taccagagaa tccaagaagc agtttaagga acctgatatt ggagtttaat     4620

ctagaaactg gatgatctca tattgattca tgatgcttaa tctttcattg aaactccaca     4680

attaaaataa caaatagaga aagaaaacta actttcctaa atatggcaaa gaaactaaca     4740

cctcatttat ttttatttct ttgtaaaaat ataaatatct caatcaaaag tacaggctca     4800

tttgtaatta tgtactcatg attgtaacag cattgagatt tcatataggc acatgtatag     4860

cagctgtttg acagtgatgg ctcttccatg taacatagca gttatcgtgt aatttagtgc     4920

cacttattgc aaagtgttac caaggggaac atttcaaatg ccttttgttt ttctttggac     4980

atcaaggtaa tttagtggac aacaaatatt aaattttaca ttatgctttt taattgtgga     5040

gaaaatgcaa aacctcatgt cttaccacaa ctttcccatg gtattgctaa ttacttagag     5100

tctctaaaat tgcccaatat tatttccctt tgcaaatggt aatttctgat aaaacaatac     5160

aaaacaaaaa aaaagcagta atcacagcca aataaatgaa acacctaatg agaattactg     5220

ttgagtaatg ctttttatta agtggcacaa agtacacact aaaaactatg caaaatatag     5280

gtaactacag tgtacgtaca tgtaagtatc ttgtacttgc tgtgtatgga tgttggaaac     5340

ccatgtaatt ataatatgca ttttgaatat tgggaaagag gaaatcttag tgtagataat     5400

agaatttgtt ttgaaatata cactggcaat attgaaatat actcagtgca atatctgcag     5460

ttctattgct ggatacttaa tgcaaaggga ttttaaagaa ttcttcagca agatccaaga     5520

ggttgctaat cttcacctct cacatactaa agcattcatt aaaaatacaa ctaattcaag     5580

gacaagttaa gtttttctta ttaatgtgac acagtaacat ttttatttgg attagttttt     5640

ggtgttattg cagagaaaga aataacctga gttttaaatt tcgattcata tctcattgaa     5700

ttgggaattc ttcaattttg tttgaaatgt gtgcatgttt tcatagattg tagcaagtac     5760

aaatgtattc aatgaaagaa catagggtag ttttaatagt taaagtcact atatcttaat     5820

gggaatttta aaatatcttt tctttttcta ttcatttttt ccctttctct ctctattcta     5880

cccccaaaca agccctttgc actcataccc ttccaaaggc aatggattga aagtagcaag     5940

ataataaaga gagttaaagg ggacaacata taacaatggg ttctaaaatc atcagcattt     6000

ttatgtattg agattattaa tattgaatgc aatagttatt ggatatagct ggtaagttct     6060

ctgccatgca tacttacaat aatccttcta cctctcactt ttaacatggg ctatgatact     6120

tcaatataaa tagaggaaat aattatttac cagatatccc aggaagcatt cttatggaac     6180

tattataaca gtgcactccc caccccctgg gaaatctcaa aagccaagtt cttcagtgta     6240

ttctatggtg tatgaatctg catttgtttt tccttttcta tcattagctt ttcctaaagg     6300

caaaatatta taactttata agaatagtcc ttctcctgcc tatttaatat ttcaatgtta     6360

atataattgt attggttttt aaaaataatt aaaatggcaa cactttgcga tccaatctga     6420

tatttaattt ttaaaatgta acaatttctt ataaattcat gctgtgtttt aagtaaaaat     6480

catgtatatg aattatttta ccaagtagta ttatctgcac gagacaaatt taagtatttt     6540

aaaaatcatc cttattaata aataatcctc atataatgca cagtattgcc acaaatgccc     6600

acttcatttt gtctgcatag acatattaag aatttttcaa tgatgtaatt taattatcct     6660

aaaagaaatg acagattctt ctgtaggaaa aaataaaaac atgaatatct caaattataa     6720

tggttaatct ctaaaatatg cttaaagtaa gatgtttcta tgttatgtgg ttatgttatc     6780

aataatattt ggttgatctt cacatatttt atatgcatat atatatcaag aagttatata     6840

tatataactc aagaaactca agttatatat atatgtcaag aaatgtatga ttattttgga     6900

gagaatgggc ccaaatgtga aaaagatata aaaaaaacaa aaaaaacaaa aaaaaaacac     6960

tattttcccc tacgaaatat actgtatatt tcaaaagaag aaaagttaaa agatatttga     7020

agattgcagg ggcaaaacaa aaacctacca gggctcagca cttaagcact tttcccacat     7080

ccagggtcaa agcagcagta actacatgga cttttaagtg cggtatgaaa tgcaacatta     7140

cgcttacaaa cagtactgtc aaacctcaaa tgctttcttt cttcagatgc tttttcgtgt     7200

acatgatact agtagacact tttctcttta tatttactga tagtgaaaat catacgcaat     7260

aaaatattga tgtttgaagg cagtggtcac caattggtta aaaaactatg aaatgtaaac     7320

tgaattgtta tatctctatc ctttttgctt ttctctgtgt ttttaatgta tggaataaat     7380

ctcataaata gaaagaaaaa taatctagaa atttttcaaa gctagtactc tttctcctta     7440

taaatgtaca caattttaat ctttttacaa atttatttaa ctgtacctac tgtacttatt     7500

gtagattcaa tgacgcagtt aagtcatcac ccaaggattt atgaatttga gattactgac     7560

ctgttttctt catattgcat tcacatcaat atttgtgaat ttgttgttca gcttttcatt     7620

caaacaaaaa atattccctc aagaaagctc catttttatc ataaacattt caacataacc     7680

aacattagaa caagtctgcc atgttaaaaa taatttaaag acttatctct gaaaacggta     7740

tccagaaacg caggtgttcc cagtaatgta gcttcaaaaa taaaatgtgc tatttatatg     7800

acatgaaatt cataactttt ggaagggtat atttatgaca gcataaaaaa taaattctgt     7860

gctataaaga agatccaaca aattaaccat ataagcacag aaaatagaga aacacagtta     7920

ttgaatctac tcttgtcatt aacattttca aaaaacaaaa tgcatattgt aatatttggt     7980

acatgacact tgcatgttga tatgcctata tacttacaaa gtattcaatg tgtacttagc     8040

ggcgcttaaa atatgtcatg tacaactctt ataaacattt ttacagggtt cccatttgca     8100

cttcatcttt cagtaaagtc ttgtcagaaa aaaattgtct gataaatatg gaaaaataaa     8160

atttgaattt tagttatctg ttggacatta ctgaattgtc tattcattta gtacattttc     8220

ttaaccttga aaacagacat tgaaagatgg aactttcttt tttccagtga caggtcatta     8280

aatcgatggt acaaaacata cttctttatg ccaaacacat tattttgaat accttttttt     8340

caacttcata cattatccat ccattttagt tttcctcgat gatgcccatt ttctttgtaa     8400

atttctaagt ggaagtttta aaaattaagc atcagtaaaa taaatgttat cttatttgta     8460

caacatttaa tcgttattcc ttggaatata tgaaccttgt aaagtgatga ctaagggtca     8520

aaaaaaatgt tgctgactta gggaaatttg cttgagaatg ccaaaatttt aaaactctgt     8580

aaaggtaatt ttacattcac ttatgtgtgt ttactaatgt tgagtaggaa cagaagcaaa     8640

aatacctaaa cctatttttt ttaaccttca cactctaacc agtattatat atttcagcta     8700

cctaagataa tgcaattaat catatatcca acctaagctt ctgccaataa ggatttcaga     8760

taagctttta aatttatgga ggattttctt tgtgtctttg gaagttcact taccataaag     8820

tattttatag tctactttaa ataacagatt ttgttacaca gggtaagcca aaggctgtac     8880

aagatttagt gtcattgggt ctcatatttg tgttagacca tgaaatattc cattaaaatt     8940

tatctgtaaa tacaaggcaa                                                 8960


<210>  2165
<211>  5245
<212>  DNA
<213>  homo sapiens

<400>  2165
ggctgcatcg acagcttgca acactcggca tcttttctgg aggcgcctcc ttcagcagcc       60

gcagatggca tccggctgcg ggctcggggc tcgcaattga ttctccccct tgcccacctc      120

gagtccacgg acgcacctct cccttcccct cctcccttcg cgcttctggg tctgagccca      180

gctcgcgacc gccgggcaga ggatcagtcg cggcggccga ggctgagcag cagcgctctc      240

gctccctgac ctggggagaa gcgcccaccc gggagagctg atccccggct gcctccagcg      300

ccccccacct tttgcactcc aagccggggg ctccagagac cccgctcccc aggcgccact      360

atgctggacc cttcgtccag cgaagaagaa tcggatgaga tcgtggagga ggagagcggc      420

aaggaggtgc tcggctcggc cccgtccggc gcgcgcctgt ctcccagccg taccagcgag      480

ggctcggccg gcagcgccgg gctggggggc ggcggcgccg gcgccggagc cggggtgggt      540

gcaggcggcg gcgggggcag cggcgcgagc agcggcggcg gggccggggg gctgcaaccc      600

agcagccgcg ctggcggcgg ccggccctcc agccccagcc cgtcggtggt gagcgagaag      660

gagaaggaag agttggagcg gctgcagaaa gaggaggagg agaggaagaa gaggctgcag      720

ctgtatgtgt tcgtgatgcg ctgcatcgcc taccccttta atgccaagca gcccaccgac      780

atggctcgcc ggcagcagaa gatcagcaaa cagcagctgc agacagtcaa ggaccggttt      840

caggctttcc tcaatgggga aacccagatc atggctgacg aagccttcat gaacgctgtg      900

cagagttact atgaggtgtt cctgaagagc gaccgtgtgg cccgcatggt tcagagtgga      960

ggctgttccg ccaacgactc ccgggaggtc ttcaagaagc acattgagaa gagagtgcgc     1020

agcctgcctg agattgacgg cctcagcaag gagactgtgc tgagctcctg gatggccaaa     1080

tttgatgcca tctaccgtgg agaagaggac ccgcggaagc agcaggcccg gatgacagcc     1140

agcgcagcct ccgagctgat tctgagcaag gagcaactct atgagatgtt ccagaacatt     1200

cttgggatca agaagttcga acatcagctc ctttacaatg cctgccagct ggacaatcca     1260

gatgagcaag cagcccagat cagacgagag ctggatggac gtctacaaat ggcagaccaa     1320

atagccaggg aacgcaaatt tcccaagttt gtatccaaag aaatggaaaa catgtacatt     1380

gaggagctga agtcatctgt caacctgctc atggccaact tggagagcat gccggtatcc     1440

aaaggcgggg agttcaagct ccagaaactc aaacgcagcc acaatgcttc catcatcgac     1500

atgggcgagg agagtgagaa ccagctctcc aagtcagatg tcgtgctgtc tttctcattg     1560

gaggtggtaa ttatggaagt ccaaggcctc aaatctttgg ctccaaatcg catcgtatat     1620

tgcacaatgg aggtggaagg aggagagaaa ctacagactg atcaggccga ggcttctaaa     1680

ccaacctggg gcacccaggg tgacttctcc acaacccatg cactgccagc tgtgaaggtg     1740

aagctgttca cagagagcac aggcgtcctg gcgttggagg acaaggagct tgggcgggtt     1800

attctccatc ccaccccgaa cagccccaaa cagtcagagt ggcacaaaat gacagtctcc     1860

aaaaactgcc ccgaccaaga tctcaaaatc aaacttgctg tccgaatgga taagcctcaa     1920

aacatgaagc attctgggta tttatgggcc atcggtaaga atgtctggaa gagatggaag     1980

aaaaggtttt ttgtattggt gcaggtcagt cagtacacgt ttgccatgtg cagttatcgg     2040

gagaagaaag cggagcctca ggaacttcta caattggatg gctacactgt ggattacacc     2100

gacccccagc caggtttgga gggtggccga gccttcttca atgctgtcaa ggagggagac     2160

accgtgatat ttgccagtga cgatgaacaa gaccgcatcc tgtgggtcca ggccatgtat     2220

cgggccacgg ggcagtcaca caagcctgtg cccccgaccc aagtccagaa actcaacgcc     2280

aagggaggaa atgtacctca gctggatgcc cctatctctc aattttacgc agatagagct     2340

caaaaacatg gcatggatga atttatctct tccaacccct gtaactttga ccacgcttcc     2400

ctctttgaga tgggctggtt cagtcctggc caggtgtttg tactagacga gtattgcgcc     2460

cgaaatggag tccgggggtg tcaccgacat ctctgctacc tcagagactt gcttgaacgg     2520

gcagaaaatg gcgccatgat cgaccccacc cttcttcact acagctttgc cttctgtgca     2580

tcccatgtcc atgggaacag gcctgatgga attggaactg tgactgttga agaaaaggaa     2640

cgttttgaag aaatcaaaga gaggctccga gttctgctag aaaatcagat tacacatttt     2700

aggtattgct ttccatttgg tcgacctgaa ggtgctttga aagctactct ctcactcttg     2760

gaaagggttt tgatgaaaga tattgttacc ccagtgccac aagaggaggt aaaaacagtt     2820

atccgtaaat gtctggaaca ggctgcgtta gtcaactatt ctcggctctc agagtatgcc     2880

aaaatcgaag aaaatgtagg ccggttaatc actcctgcca aaaagcttga agatacaata     2940

cgtcttgctg aactagtcat tgaagttctt cagcaaaatg aggagcacca cgcagaggcc     3000

tttgcgtggt ggtcagattt aatggtggag catgcggaga cgttcctgtc actctttgca     3060

gtagacatgg atgcagcctt agaggtgcaa cctccagaca catgggacag ttttccacta     3120

tttcagctgc tgaatgattt tctccgtact gactataatt tgtgcaatgg aaaatttcac     3180

aaacacctgc aagacctgtt tgccccactt gttgttagat atgtggatct gatggagtcc     3240

tcaattgcac aatccattca caggggcttt gagcgggagt catgggaacc agtcaataat     3300

gggtcaggca cctcagaaga tctgttttgg aaacttgacg cccttcagac cttcattcgg     3360

gacctgcact ggcctgaaga agagtttgga aagcacctgg aacaacggct gaagttgatg     3420

gcaagtgaca tgatcgaatc ttgtgtcaaa agaaccagga ttgcatttga agttaagctg     3480

caaaaaacca gtcgatcaac agattttcga gtcccacagt caatatgcac catgtttaat     3540

gttatggttg atgccaaagc tcaatcaaca aaactttgca gcatggaaat gggccaagag     3600

catcaatacc attcaaaaat agacgaacta attgaagaaa ctgttaaaga aatgataaca     3660

ctcttggttg caaagttcgt tactatcttg gaaggagtgc tggcaaaatt atccagatat     3720

gacgaaggga ctttgttttc ttcttttctg tcatttaccg tgaaggcagc ttccaaatat     3780

gtggatgtac ctaaacccgg gatggacgtg gccgacgcct acgtgacttt cgtccgccat     3840

tctcaggatg tcctgcgtga taaggtcaat gaggagatgt acatagaaag gttatttgat     3900

caatggtaca acagctccat gaacgtgatc tgcacctggt tgacggaccg gatggactta     3960

cagcttcata tttatcagtt gaaaacacta attaggatgg taaagaaaac ctacagagat     4020

ttccgattgc aaggggtcct ggactccacc ttaaacagca agacctatga aacgatccgg     4080

aaccgtctca ctgtggagga agccacagca tcagtgagtg aaggtggggg actgcagggc     4140

atcagcatga aggacagcga tgaggaagac gaagaagacg attagaccat ttggtcctag     4200

agtctgctgg gacagagtcc tgtaatcagt gcatgtcctt agtctgttag ttaaacccat     4260

taggaatttt ctgtcaacta ccatgcccat gagatgttta tcaatacaac tgccatttta     4320

gctatgtggt accaagatta gcaaatgacc ttcatatcca ctgatttcct gatgtccatg     4380

tctatatgtt tacaagcaat atggagcacc attctttaaa tactgttcat ggagaataca     4440

tagtctaacc actaggcgtg tccctgttat cagcaaagat caatgatgct tcattcatgt     4500

actatgtatg cattggtggt aaatggatgt gagggcaagt acatcaagta cattcactct     4560

gtttcacgta tgtggatgcc agttaattaa atgagtacgt aaataaatta attaaaacac     4620

atagatctgc tttgtgtttt tatttttatt ttttgaaaaa caaaaggcaa gtctccaaca     4680

attaactttt gatgctttct gttcccctaa aaccaaaaaa tgaacccctt gtgtcgttgt     4740

taacccatcc tttcatttac tcatataatt agccaaaaaa aaaaggatgg ctacatacca     4800

atggattgat tctcttaatt gccacggcaa gggggcgatc ctatcatgac ttaacatcaa     4860

gcgcgcagtt caaaactact gtcttctgtc aaagttttct cctcttaaat gttattttgc     4920

ttttacgtct caactgtgta tgtaaaaaaa atgaatattt aaattacaac cctagactaa     4980

aaatgtgttt ataataagat gtggatattt ccttcagtag attgtaacca taatttaaat     5040

tattttgttc cacactgttt tttatatctg tcatgtacat tgcattttga tctgtaactg     5100

cacaaccctg gggtttgctg cagagctatt tctttccatg taaagtagtg gatccatctt     5160

gcttttgcct tatataaagc ctacagttat ggaagtgtgg aaaactgtgg cttctcaata     5220

aatattcaga tgtcctaaga atata                                           5245


<210>  2166
<211>  5482
<212>  DNA
<213>  homo sapiens

<400>  2166
ggctgcatcg acagcttgca acactcggca tcttttctgg aggcgcctcc ttcagcagcc       60

gcagatggca tccggctgcg ggctcggggc tcgcaattga ttctccccct tgcccacctc      120

gagtccacgg acgcacctct cccttcccct cctcccttcg cgcttctggg tctgagccca      180

gctcgcgacc gccgggcaga ggatcagtcg cggcggccga ggctgagcag cagcgctctc      240

gctccctgac ctggggagaa gcgcccaccc gggagagctg atccccggct gcctccagcg      300

ccccccacct tttgcactcc aagccggggg ctccagagac cccgctcccc aggcgccact      360

atgctggacc cttcgtccag cgaagaagaa tcggatgaga tcgtggagga ggagagcggc      420

aaggaggtgc tcggctcggc cccgtccggc gcgcgcctgt ctcccagccg taccagcgag      480

ggctcggccg gcagcgccgg gctggggggc ggcggcgccg gcgccggagc cggggtgggt      540

gcaggcggcg gcgggggcag cggcgcgagc agcggcggcg gggccggggg gctgcaaccc      600

agcagccgcg ctggcggcgg ccggccctcc agccccagcc cgtcggtggt gagcgagaag      660

gagaaggaag agttggagcg gctgcagaaa gaggaggagg agaggaagaa gaggctgcag      720

ctgtatgtgt tcgtgatgcg ctgcatcgcc taccccttta atgccaagca gcccaccgac      780

atggctcgcc ggcagcagaa gatcagcaaa cagcagctgc agacagtcaa ggaccggttt      840

caggctttcc tcaatgggga aacccagatc atggctgacg aagccttcat gaacgctgtg      900

cagagttact atgaggtgtt cctgaagagc gaccgtgtgg cccgcatggt tcagagtgga      960

ggctgttccg ccaacgactc ccgggaggtc ttcaagaagc acattgagaa gagagtgcgc     1020

agcctgcctg agattgacgg cctcagcaag gagactgtgc tgagctcctg gatggccaaa     1080

tttgatgcca tctaccgtgg agaagaggac ccgcggaagc agcaggcccg gatgacagcc     1140

agcgcagcct ccgagctgat tctgagcaag gagcaactct atgagatgtt ccagaacatt     1200

cttgggatca agaagttcga acatcagctc ctttacaatg cctgccagct ggacaatcca     1260

gatgagcaag cagcccagat cagacgagag ctggatggac gtctacaaat ggcagaccaa     1320

atagccaggg aacgcaaatt tcccaagttt gtatccaaag aaatggaaaa catgtacatt     1380

gaggagctga agtcatctgt caacctgctc atggccaact tggagagcat gccggtatcc     1440

aaaggcgggg agttcaagct ccagaaactc aaacgcagcc acaatgcttc catcatcgac     1500

atgggcgagg agagtgagaa ccagctctcc aagtcagatg tcgtgctgtc tttctcattg     1560

gaggtggtaa ttatggaagt ccaaggcctc aaatctttgg ctccaaatcg catcgtatat     1620

tgcacaatgg aggtggaagg aggagagaaa ctacagactg atcaggccga ggcttctaaa     1680

ccaacctggg gcacccaggg tgacttctcc acaacccatg cactgccagc tgtgaaggtg     1740

aagctgttca cagagagcac aggcgtcctg gcgttggagg acaaggagct tgggcgggtt     1800

attctccatc ccaccccgaa cagccccaaa cagtcagagt ggcacaaaat gacagtctcc     1860

aaaaactgcc ccgaccaaga tctcaaaatc aaacttgctg tccgaatgga taagcctcaa     1920

aacatgaagc attctgggta tttatgggcc atcggtaaga atgtctggaa gagatggaag     1980

aaaaggtttt ttgtattggt gcaggtcagt cagtacacgt ttgccatgtg cagttatcgg     2040

gagaagaaag cggagcctca ggaacttcta caattggatg gctacactgt ggattacacc     2100

gacccccagc caggtttgga gggtggccga gccttcttca atgctgtcaa ggagggagac     2160

accgtgatat ttgccagtga cgatgaacaa gaccgcatcc tgtgggtcca ggccatgtat     2220

cgggccacgg ggcagtcaca caagcctgtg cccccgaccc aagtccagaa actcaacgcc     2280

aagggaggaa atgtacctca gctggatgcc cctatctctc aattttacgc agatagagct     2340

caaaaacatg gcatggatga atttatctct tccaacccct gtaactttga ccacgcttcc     2400

ctctttgaga tggtacaacg ccttactttg gatcacagac ttaatgattc ctattcttgc     2460

ctgggctggt tcagtcctgg ccaggtgttt gtactagacg agtattgcgc ccgaaatgga     2520

gtccgggggt gtcaccgaca tctctgctac ctcagagact tgcttgaacg ggcagaaaat     2580

ggcgccatga tcgaccccac ccttcttcac tacagctttg ccttctgtgc atcccatgtc     2640

catgggaaca ggcctgatgg aattggaact gtgactgttg aagaaaagga acgttttgaa     2700

gaaatcaaag agaggctccg agttctgcta gaaaatcaga ttacacattt taggtattgc     2760

tttccatttg gtcgacctga aggtgctttg aaagctactc tctcactctt ggaaagggtt     2820

ttgatgaaag atattgttac cccagtgcca caagaggagg taaaaacagt tatccgtaaa     2880

tgtctggaac aggctgcgtt agtcaactat tctcggctct cagagtatgc caaaatcgaa     2940

gagaatcaaa aggatgcaga aaatgtaggc cggttaatca ctcctgccaa aaagcttgaa     3000

gatacaatac gtcttgctga actagtcatt gaagttcttc agcaaaatga ggagcaccac     3060

gcagagccac atgttgataa aggagaagcc tttgcgtggt ggtcagattt aatggtggag     3120

catgcggaga cgttcctgtc actctttgca gtagacatgg atgcagcctt agaggtgcaa     3180

cctccagaca catgggacag ttttccacta tttcagctgc tgaatgattt tctccgtact     3240

gactataatt tgtgcaatgg aaaatttcac aaacacctgc aagacctgtt tgccccactt     3300

gttgttagat atgtggatct gatggagtcc tcaattgcac aatccattca caggggcttt     3360

gagcgggagt catgggaacc agtcaagagt ttaaccagta acctacccaa tgtgaaccta     3420

cccaatgtga accttcccaa agtaccaaat ctaccagtta acatccctct aggcatccca     3480

caaatgccta ctttttcggc accgtcatgg atggctgcta tatatgatgc ggataatggg     3540

tcaggcacct cagaagatct gttttggaaa cttgacgccc ttcagacctt cattcgggac     3600

ctgcactggc ctgaagaaga gtttggaaag cacctggaac aacggctgaa gttgatggca     3660

agtgacatga tcgaatcttg tgtcaaaaga accaggattg catttgaagt taagctgcaa     3720

aaaaccagtc gatcaacaga ttttcgagtc ccacagtcaa tatgcaccat gtttaatgtt     3780

atggttgatg ccaaagctca atcaacaaaa ctttgcagca tggaaatggg ccaagagcat     3840

caataccatt caaaaataga cgaactaatt gaagaaactg ttaaagaaat gataacactc     3900

ttggttgcaa agttcgttac tatcttggaa ggagtgctgg caaaattatc cagatatgac     3960

gaagggactt tgttttcttc ttttctgtca tttaccgtga aggcagcttc caaatatgtg     4020

gatgtaccta aacccgggat ggacgtggcc gacgcctacg tgactttcgt ccgccattct     4080

caggatgtcc tgcgtgataa ggtcaatgag gagatgtaca tagaaaggtt atttgatcaa     4140

tggtacaaca gctccatgaa cgtgatctgc acctggttga cggaccggat ggacttacag     4200

cttcatattt atcagttgaa aacactaatt aggatggtaa agaaaaccta cagagatttc     4260

cgattgcaag gggtcctgga ctccacctta aacagcaaga cctatgaaac gatccggaac     4320

cgtctcactg tggaggaagc cacagcatca gtgagtgaag gtgggggact gcagggcatc     4380

agcatgaagg acagcgatga ggaagacgaa gaagacgatt agaccatttg gtcctagagt     4440

ctgctgggac agagtcctgt aatcagtgca tgtccttagt ctgttagtta aacccattag     4500

gaattttctg tcaactacca tgcccatgag atgtttatca atacaactgc cattttagct     4560

atgtggtacc aagattagca aatgaccttc atatccactg atttcctgat gtccatgtct     4620

atatgtttac aagcaatatg gagcaccatt ctttaaatac tgttcatgga gaatacatag     4680

tctaaccact aggcgtgtcc ctgttatcag caaagatcaa tgatgcttca ttcatgtact     4740

atgtatgcat tggtggtaaa tggatgtgag ggcaagtaca tcaagtacat tcactctgtt     4800

tcacgtatgt ggatgccagt taattaaatg agtacgtaaa taaattaatt aaaacacata     4860

gatctgcttt gtgtttttat ttttattttt tgaaaaacaa aaggcaagtc tccaacaatt     4920

aacttttgat gctttctgtt cccctaaaac caaaaaatga accccttgtg tcgttgttaa     4980

cccatccttt catttactca tataattagc caaaaaaaaa aggatggcta cataccaatg     5040

gattgattct cttaattgcc acggcaaggg ggcgatccta tcatgactta acatcaagcg     5100

cgcagttcaa aactactgtc ttctgtcaaa gttttctcct cttaaatgtt attttgcttt     5160

tacgtctcaa ctgtgtatgt aaaaaaaatg aatatttaaa ttacaaccct agactaaaaa     5220

tgtgtttata ataagatgtg gatatttcct tcagtagatt gtaaccataa tttaaattat     5280

tttgttccac actgtttttt atatctgtca tgtacattgc attttgatct gtaactgcac     5340

aaccctgggg tttgctgcag agctatttct ttccatgtaa agtagtggat ccatcttgct     5400

tttgccttat ataaagccta cagttatgga agtgtggaaa actgtggctt ctcaataaat     5460

attcagatgt cctaagaata ta                                              5482


<210>  2167
<211>  5365
<212>  DNA
<213>  homo sapiens

<400>  2167
ggctgcatcg acagcttgca acactcggca tcttttctgg aggcgcctcc ttcagcagcc       60

gcagatggca tccggctgcg ggctcggggc tcgcaattga ttctccccct tgcccacctc      120

gagtccacgg acgcacctct cccttcccct cctcccttcg cgcttctggg tctgagccca      180

gctcgcgacc gccgggcaga ggatcagtcg cggcggccga ggctgagcag cagcgctctc      240

gctccctgac ctggggagaa gcgcccaccc gggagagctg atccccggct gcctccagcg      300

ccccccacct tttgcactcc aagccggggg ctccagagac cccgctcccc aggcgccact      360

atgctggacc cttcgtccag cgaagaagaa tcggatgaga tcgtggagga ggagagcggc      420

aaggaggtgc tcggctcggc cccgtccggc gcgcgcctgt ctcccagccg taccagcgag      480

ggctcggccg gcagcgccgg gctggggggc ggcggcgccg gcgccggagc cggggtgggt      540

gcaggcggcg gcgggggcag cggcgcgagc agcggcggcg gggccggggg gctgcaaccc      600

agcagccgcg ctggcggcgg ccggccctcc agccccagcc cgtcggtggt gagcgagaag      660

gagaaggaag agttggagcg gctgcagaaa gaggaggagg agaggaagaa gaggctgcag      720

ctgtatgtgt tcgtgatgcg ctgcatcgcc taccccttta atgccaagca gcccaccgac      780

atggctcgcc ggcagcagaa gatcagcaaa cagcagctgc agacagtcaa ggaccggttt      840

caggctttcc tcaatgggga aacccagatc atggctgacg aagccttcat gaacgctgtg      900

cagagttact atgaggtgtt cctgaagagc gaccgtgtgg cccgcatggt tcagagtgga      960

ggctgttccg ccaacgactc ccgggaggtc ttcaagaagc acattgagaa gagagtgcgc     1020

agcctgcctg agattgacgg cctcagcaag gagactgtgc tgagctcctg gatggccaaa     1080

tttgatgcca tctaccgtgg agaagaggac ccgcggaagc agcaggcccg gatgacagcc     1140

agcgcagcct ccgagctgat tctgagcaag gagcaactct atgagatgtt ccagaacatt     1200

cttgggatca agaagttcga acatcagctc ctttacaatg cctgccagct ggacaatcca     1260

gatgagcaag cagcccagat cagacgagag ctggatggac gtctacaaat ggcagaccaa     1320

atagccaggg aacgcaaatt tcccaagttt gtatccaaag aaatggaaaa catgtacatt     1380

gaggagctga agtcatctgt caacctgctc atggccaact tggagagcat gccggtatcc     1440

aaaggcgggg agttcaagct ccagaaactc aaacgcagcc acaatgcttc catcatcgac     1500

atgggcgagg agagtgagaa ccagctctcc aagtcagatg tcgtgctgtc tttctcattg     1560

gaggtggtaa ttatggaagt ccaaggcctc aaatctttgg ctccaaatcg catcgtatat     1620

tgcacaatgg aggtggaagg aggagagaaa ctacagactg atcaggccga ggcttctaaa     1680

ccaacctggg gcacccaggg tgacttctcc acaacccatg cactgccagc tgtgaaggtg     1740

aagctgttca cagagagcac aggcgtcctg gcgttggagg acaaggagct tgggcgggtt     1800

attctccatc ccaccccgaa cagccccaaa cagtcagagt ggcacaaaat gacagtctcc     1860

aaaaactgcc ccgaccaaga tctcaaaatc aaacttgctg tccgaatgga taagcctcaa     1920

aacatgaagc attctgggta tttatgggcc atcggtaaga atgtctggaa gagatggaag     1980

aaaaggtttt ttgtattggt gcaggtcagt cagtacacgt ttgccatgtg cagttatcgg     2040

gagaagaaag cggagcctca ggaacttcta caattggatg gctacactgt ggattacacc     2100

gacccccagc caggtttgga gggtggccga gccttcttca atgctgtcaa ggagggagac     2160

accgtgatat ttgccagtga cgatgaacaa gaccgcatcc tgtgggtcca ggccatgtat     2220

cgggccacgg ggcagtcaca caagcctgtg cccccgaccc aagtccagaa actcaacgcc     2280

aagggaggaa atgtacctca gctggatgcc cctatctctc aattttacgc agatagagct     2340

caaaaacatg gcatggatga atttatctct tccaacccct gtaactttga ccacgcttcc     2400

ctctttgaga tggtacaacg ccttactttg gatcacagac ttaatgattc ctattcttgc     2460

ctgggctggt tcagtcctgg ccaggtgttt gtactagacg agtattgcgc ccgaaatgga     2520

gtccgggggt gtcaccgaca tctctgctac ctcagagact tgcttgaacg ggcagaaaat     2580

ggcgccatga tcgaccccac ccttcttcac tacagctttg ccttctgtgc atcccatgtc     2640

catgggaaca ggcctgatgg aattggaact gtgactgttg aagaaaagga acgttttgaa     2700

gaaatcaaag agaggctccg agttctgcta gaaaatcaga ttacacattt taggtattgc     2760

tttccatttg gtcgacctga aggtgctttg aaagctactc tctcactctt ggaaagggtt     2820

ttgatgaaag atattgttac cccagtgcca caagaggagg taaaaacagt tatccgtaaa     2880

tgtctggaac aggctgcgtt agtcaactat tctcggctct cagagtatgc caaaatcgaa     2940

gggaaaaaga gagaaatgta tgagcatcct gtcttctgct tggcctccca agtgatggat     3000

ttaaccattc aaaatgtagg ccggttaatc actcctgcca aaaagcttga agatacaata     3060

cgtcttgctg aactagtcat tgaagttctt cagcaaaatg aggagcacca cgcagaggcc     3120

tttgcgtggt ggtcagattt aatggtggag catgcggaga cgttcctgtc actctttgca     3180

gtagacatgg atgcagcctt agaggtgcaa cctccagaca catgggacag ttttccacta     3240

tttcagctgc tgaatgattt tctccgtact gactataatt tgtgcaatgg aaaatttcac     3300

aaacacctgc aagacctgtt tgccccactt gttgttagat atgtggatct gatggagtcc     3360

tcaattgcac aatccattca caggggcttt gagcgggagt catgggaacc agtcaataat     3420

gggtcaggca cctcagaaga tctgttttgg aaacttgacg cccttcagac cttcattcgg     3480

gacctgcact ggcctgaaga agagtttgga aagcacctgg aacaacggct gaagttgatg     3540

gcaagtgaca tgatcgaatc ttgtgtcaaa agaaccagga ttgcatttga agttaagctg     3600

caaaaaacca gtcgatcaac agattttcga gtcccacagt caatatgcac catgtttaat     3660

gttatggttg atgccaaagc tcaatcaaca aaactttgca gcatggaaat gggccaagag     3720

catcaatacc attcaaaaat agacgaacta attgaagaaa ctgttaaaga aatgataaca     3780

ctcttggttg caaagttcgt tactatcttg gaaggagtgc tggcaaaatt atccagatat     3840

gacgaaggga ctttgttttc ttcttttctg tcatttaccg tgaaggcagc ttccaaatat     3900

gtggatgtac ctaaacccgg gatggacgtg gccgacgcct acgtgacttt cgtccgccat     3960

tctcaggatg tcctgcgtga taaggtcaat gaggagatgt acatagaaag gttatttgat     4020

caatggtaca acagctccat gaacgtgatc tgcacctggt tgacggaccg gatggactta     4080

cagcttcata tttatcagtt gaaaacacta attaggatgg taaagaaaac ctacagagat     4140

ttccgattgc aaggggtcct ggactccacc ttaaacagca agacctatga aacgatccgg     4200

aaccgtctca ctgtggagga agccacagca tcagtgagtg aaggtggggg actgcagggc     4260

atcagcatga aggacagcga tgaggaagac gaagaagacg attagaccat ttggtcctag     4320

agtctgctgg gacagagtcc tgtaatcagt gcatgtcctt agtctgttag ttaaacccat     4380

taggaatttt ctgtcaacta ccatgcccat gagatgttta tcaatacaac tgccatttta     4440

gctatgtggt accaagatta gcaaatgacc ttcatatcca ctgatttcct gatgtccatg     4500

tctatatgtt tacaagcaat atggagcacc attctttaaa tactgttcat ggagaataca     4560

tagtctaacc actaggcgtg tccctgttat cagcaaagat caatgatgct tcattcatgt     4620

actatgtatg cattggtggt aaatggatgt gagggcaagt acatcaagta cattcactct     4680

gtttcacgta tgtggatgcc agttaattaa atgagtacgt aaataaatta attaaaacac     4740

atagatctgc tttgtgtttt tatttttatt ttttgaaaaa caaaaggcaa gtctccaaca     4800

attaactttt gatgctttct gttcccctaa aaccaaaaaa tgaacccctt gtgtcgttgt     4860

taacccatcc tttcatttac tcatataatt agccaaaaaa aaaaggatgg ctacatacca     4920

atggattgat tctcttaatt gccacggcaa gggggcgatc ctatcatgac ttaacatcaa     4980

gcgcgcagtt caaaactact gtcttctgtc aaagttttct cctcttaaat gttattttgc     5040

ttttacgtct caactgtgta tgtaaaaaaa atgaatattt aaattacaac cctagactaa     5100

aaatgtgttt ataataagat gtggatattt ccttcagtag attgtaacca taatttaaat     5160

tattttgttc cacactgttt tttatatctg tcatgtacat tgcattttga tctgtaactg     5220

cacaaccctg gggtttgctg cagagctatt tctttccatg taaagtagtg gatccatctt     5280

gcttttgcct tatataaagc ctacagttat ggaagtgtgg aaaactgtgg cttctcaata     5340

aatattcaga tgtcctaaga atata                                           5365


<210>  2168
<211>  2293
<212>  DNA
<213>  homo sapiens

<400>  2168
atcgtttccc cgcgcgcagg tccgcgggga ggggcggcct gccgaccggc ccaccccagg       60

gcgttcctga agggcgtcct cggccgcccc caccgcctcc cagatgtact atgcggtttc      120

ccaggcgcgc gtgaacgcgg tccccgggac catgctgcgg ccacagcggc ccggagactt      180

gcagctcggg gcctccctct acgagctggt gggctacagg cagccgccct cctcctcctc      240

ctcctccacc tcctccacct cctccacttc ctcctcctcc acgacggccc ccctcctccc      300

caaggctgcg cgcgagaagc cggaggcgcc ggccgagcct ccaggccccg ggcccgggtc      360

aggcgcgcac ccgggcggca gcgcccggcc ggacgccaag gaggagcagc agcagcagct      420

gcggcgcaag atcaacagcc gcgagcggaa gcgcatgcag gacctgaacc tggccatgga      480

cgccctgcgc gaggtcatcc tgccctactc agcggcgcac tgccagggcg cgcccggccg      540

caagctctcc aagatagcca cgctgctgct cgcccgcaac tacatcctac tgctgggcag      600

ctcgctgcag gagctgcgcc gcgcgctggg cgagggcgcc gggcccgccg cgccgcgcct      660

gctgctggcc gggctgcccc tgctcgccgc cgcgcccggc tccgtgctgc tggcgcccgg      720

cgccgtagga ccccccgacg cgctgcgccc cgccaagtac ctgtcgctgg cgctggacga      780

gccgccgtgc ggccagttcg ctctccccgg cggcggcgca ggcggccccg gcctctgcac      840

ctgcgccgtg tgcaagttcc cgcacctggt cccggccagc ctgggcctgg ccgccgtgca      900

ggcgcaattc tccaagtgag ggcgggcctg ggcctggggc gcgacctcgg cccggcctcc      960

cttcgctcag cttctccgcg cccctgctcc ctgcgtctgg gagagcgagg ccgagcaagg     1020

aaagcatttc gaaccttcca gtccagagga agggactgtc gggcaccccc ttccccgccc     1080

ccacccctgg gacgttaaag tgaccagagc ggatgttcga tggcgcctcg gggcagtttg     1140

gggttctggg tcggttccag cggctttagg cagaaagtgc tcgctctcac ccagcacatc     1200

tctctccttg tccctggagt tgcgcgcttc gcggggccga tgtagaactt agggcgcctt     1260

gccgtggttg gcgcgccccg ggtgcagcga gaggccatcc ccgagcgcta cctccccgga     1320

gcggagcacg ccggctccca gtactagggg ctgcgctcga gcagtggcgg gggcggaggg     1380

gtggttcttt tccttctcct ccgccagagg ccacgggcgc ccttgttccc gccggccagg     1440

tcctatcaaa ggaggctgcc ggaactcaag aggcagaaaa agaccagtta ggcggtgcag     1500

acggtctggg acgtggcaga cggacggacc ctcggcggac aggtggtcgg cgtcggggtg     1560

cggtgggtag gggcgaggac aacgcagggt gcgctgggtt gggacgtggg tccacttttg     1620

tagaccagct gtttggagag ctgtatttaa gactcgcgta tccagtgttt tgtcgcagag     1680

agttttcgct cttaaatcct gggggtttct tagaaagcaa cttagaactc gagattcacc     1740

tttcgtttcc ctttccccaa aagtagcgta accaacattt aagcttgctt aaaaacgaaa     1800

accaaccgcc ttgcatccag tgttcccgat ttactaaaat aggtaaccag gcgtctcaca     1860

gtcgccgtcc tgtcaagagc gctaatgaac gttctcatta acacgcagga gtaccgggag     1920

ccctgaaccg cccgctgctc ggcggatccc agctgcggtg gcgacggcgg gaaggcgctt     1980

tccgctgttc ctcagcgggc cgggcccttg accagcgcgg cccgcaggtc ttccttctcg     2040

ccgtcttgca gttgaagagc tacatacgta gtcagtttcg atttgttaca gacgttaaca     2100

aattccttta cccaaggtta tgctatgacc tttccgcagt ttactttgat tttctatgtt     2160

taaggttttg gttgttggta gtagccgaat ttaactggca ctttatttta cttctaacct     2220

tgtttcctga cggtgtacag aatcaacaaa ataaaacatt taaagtctga ttttttacaa     2280

aaaaaaaaaa aaa                                                        2293


<210>  2169
<211>  2521
<212>  DNA
<213>  homo sapiens

<400>  2169
aaaaaccggc cgagccccta aaggtgcgga tgcttattat agatcgacgc gacaccagcg       60

cccggtgcca ggttctcccc tgaggctttt cggagcgagc tcctcaaatc gcatccagat      120

tttcgggtcc gagggaagga ggaccctgcg aaagctgcga cgactatctt cccctggggc      180

catggactcg gacgccagcc tggtgtccag ccgcccgtcg tcgccagagc ccgatgacct      240

ttttctgccg gcccggagta agggcagcag cggcagcgcc ttcactgggg gcaccgtgtc      300

ctcgtccacc ccgagtgact gcccgccgga gctgagcgcc gagctgcgcg gcgctatggg      360

ctctgcgggc gcgcatcctg gggacaagct aggaggcagt ggcttcaagt catcctcgtc      420

cagcacctcg tcgtctacgt cgtcggcggc tgcgtcgtcc accaagaagg acaagaagca      480

aatgacagag ccggagctgc agcagctgcg tctcaagatc aacagccgcg agcgcaagcg      540

catgcacgac ctcaacatcg ccatggatgg cctccgcgag gtcatgccgt acgcacacgg      600

cccttcggtg cgcaagcttt ccaagatcgc cacgctgctg ctggcgcgca actacatcct      660

catgctcacc aactcgctgg aggagatgaa gcgactggtg agcgagatct acgggggcca      720

ccacgctggc ttccacccgt cggcctgcgg cggcctggcg cactccgcgc ccctgcccgc      780

cgccaccgcg cacccggcag cagcagcgca cgccgcacat caccccgcgg tgcaccaccc      840

catcctgccg cccgccgccg cagcggctgc tgccgccgct gcagccgcgg ctgtgtccag      900

cgcctctctg cccggatccg ggctgccgtc ggtcggctcc atccgtccac cgcacggcct      960

actcaagtct ccgtctgctg ccgcggccgc cccgctgggg ggcgggggcg gcggcagtgg     1020

ggcgagcggg ggcttccagc actggggcgg catgccctgc ccctgcagca tgtgccaggt     1080

gccgccgccg caccaccacg tgtcggctat gggcgccggc agcctgccgc gcctcacctc     1140

cgacgccaag tgagccgact ggcgccggcg cgttctggcg acaggggagc caggggccgc     1200

ggggaagcga ggactggcct gcgctgggct cgggagctct gtcgcgagga ggggcgcagg     1260

accatggact gggggtgggg catggtgggg attccagcat ctgcgaaccc aagcaatggg     1320

ggcgcccaca gagcagtggg gagtgagggg atgttctctc cgggacctga tcgagcgctg     1380

tctggcttta acctgagctg gtccagtaga catcgtttta tgaaaaggta ccgctgtgtg     1440

cattcctcac tagaactcat ccgacccccg acccccacct ccgggaaaag attctaaaaa     1500

cttctttccc tgagagcgtg gcctgacttg cagactcggc ttgggcagca cttcgggggg     1560

ggagggggtg ttatgggagg gggacacatt ggggccttgc tcctcttcct cctttcttgg     1620

cgggtgggag actccgggta gccgcactgc agaagcaaca gcccgaccgc gccctccagg     1680

gtcgtccctg gcccaaggcc aggggccaca agttagttgg aagccggcgt tcggtatcag     1740

aagcgctgat ggtcatatcc aatctcaata tctgggtcaa tccacaccct cttagaactg     1800

tggccgttcc tccctgtctc tcgttgattt gggagaatat ggttttctaa taaatctgtg     1860

gatgttcctt cttcaacagt atgagcaagt ttatagacat tcagagtaga accacttgtg     1920

gattggaata acccaaaact gccgatttca ggggcgggtg cattgtagtt attattttaa     1980

aatagaaact accccaccga ctcatctttc cttctctaag cacaaagtga tttggttatt     2040

ttggtacctg agaacgtaac agaattaaaa ggcagttgct gtggaaacag tttgggttat     2100

ttgggggttc tgttggcttt ttaaaatttt cttttttgga tgtgtaaatt tatcaatgat     2160

gaggtaagtg cgcaatgcta agctgtttgc tcacgtgact gccagcccca tcggagtcta     2220

agccggcttt cctctatttt ggtttatttt tgccacgttt aacacaaatg gtaaactcct     2280

ccacgtgctt cctgcgttcc gtgcaagccg cctcggcgct gcctgcgttg caaactgggc     2340

tttgtagcgt ctgccgtgta acacccttcc tctgatcgca ccgcccctcg cagagagtgt     2400

atcatctgtt ttatttttgt aaaaacaaag tgctaaataa tatttattac ttgtttggtt     2460

gcaaaaacgg aataaatgac tgagtgttga gattttaaat aaaatttaaa gtaaaaaaaa     2520

a                                                                     2521


<210>  2170
<211>  3796
<212>  DNA
<213>  homo sapiens

<400>  2170
ctctggatgg accagaatac gaggaggaag aggtggccat accgttgacc gctcctccaa       60

ctaaccagta agttaagact gctgttcagg aatttgggaa gctggctcca gaaaagaagt      120

ggaaatgaag gggtggtatc acggaaaact tgacagaacg atagcagaag aacgcctcag      180

gcaggcaggg aagtctggca gttatcttat aagagagagt gatcggaggc cagggtcctt      240

tgtactttca tttcttagcc agatgaatgt tgtcaaccat tttaggatta ttgctatgtg      300

tggagattac tacattggtg gaagacgttt ttcttcactg tcagacctaa taggttatta      360

cagtcatgtt tcttgtttgc ttaaaggaga aaaattactt tacccagttg caccaccaga      420

gccagtagaa gatagaaggc gtgtacgagc tattctacct tacacaaaag taccagacac      480

tgatgaaata agtttcttaa aaggagatat gttcattgtt cataatgaat tagaagatgg      540

atggatgtgg gttacaaatt taagaacaga tgaacaaggc cttattgttg aagacctagt      600

agaagaggtg ggccgggaag aagatccaca tgaaggaaaa atatggttcc atgggaagat      660

ttccaaacag gaagcttata atttactaat gacagttggt caagtctgca gttttcttgt      720

gaggccctca gataatactc ctggcgatta ttcactttat ttccggacca atgaaaatat      780

tcagcgattt aaaatatgtc caacgccaaa caatcagttt atgatgggag gccggtatta      840

taacagcatt ggggacatca tagatcacta tcgaaaagaa cagattgttg aaggatatta      900

tcttaaggaa cctgtaccaa tgcaggatca agaacaagta ctcaatgaca cagtggatgg      960

caaggaaatc tataatacca tccgtcgtaa aacaaaggat gccttttata aaaacattgt     1020

taagaaaggt tatcttctga aaaagggcaa aggaaaacgt tggaaaaatt tatattttat     1080

cttagagggt agtgatgccc aacttattta ttttgaaagc gaaaaacgag ctaccaaacc     1140

aaaaggatta atagatctca gtgtatgttc tgtctatgtc gttcatgata gtctctttgg     1200

caggccaaac tgttttcaga tagtagttca gcactttagt gaagaacatt acatctttta     1260

ctttgcagga gaaactccag aacaagcaga ggattggatg aaaggtctgc aggcattttg     1320

caatttacgg aaaagtagtc cagggacatc caataaacgc cttcgtcagg tcagcagcct     1380

tgttttacat attgaagaag cccataaact cccagtaaaa cattttacta atccatattg     1440

taacatctac ctgaatagtg tccaagtagc aaaaactcat gcaagggaag ggcaaaaccc     1500

agtatggtca gaagagtttg tctttgatga tcttcctcct gacatcaata gatttgaaat     1560

aactcttagt aataaaacaa agaaaagcaa agatcctgat atcttattta tgcgctgcca     1620

gttgagccga ttacagaaag ggcatgccac agatgaatgg tttctgctca gctcccatat     1680

accattaaaa ggtattgaac cagggtccct gcgtgttcga gcacgatact ctatggaaaa     1740

aatcatgcca gaagaagagt acagtgaatt taaagagctt atactgcaaa aggaacttca     1800

tgtagtctat gctttatcac atgtatgtgg acaagaccga acactactgg ccagcatcct     1860

actgaggatt tttcttcacg aaaagcttga atcgttgttg ttatgcacac taaatgacag     1920

agaaataagc atggaagatg aagccactac cctatttcga gccacaacac ttgcaagcac     1980

cttgatggag cagtatatga aagccactgc tacacagttt gttcatcatg ctttgaaaga     2040

ctctatttta aagataatgg aaagcaagca gtcttgtgag ttaagtccat caaagttaga     2100

aaaaaatgaa gatgtgaaca ctaatttaac acacctattg aacatacttt cagagcttgt     2160

ggagaaaata ttcatggctt cagaaatact tccaccgaca ttgagatata tttatgggtg     2220

tttacagaaa tctgttcagc ataagtggcc tacaaatacc accatgagaa caagagttgt     2280

tagtggtttt gtttttcttc gactcatctg tcctgccatc ctgaatccac ggatgttcaa     2340

tatcatctca gattctccat ctcctattgc tgcaagaaca ctgatattag tggctaaatc     2400

tgtgcagaac ttagcaaatc ttgtggaatt tggagctaag gagccctaca tggaaggtgt     2460

caatccattc atcaaaagca acaaacatcg tatgatcatg tttttagatg aacttgggaa     2520

tgtacctgaa cttccggaca ctacagagca ttctagaacg gacctgtccc gtgatttagc     2580

agcattgcat gagatttgcg tggctcattc agatgaactt cgaacgctca gtaatgagcg     2640

tggtgcacag cagcacgtat tgaaaaagct tctggctata acagaactgc ttcaacaaaa     2700

acaaaaccag tatacaaaaa ccaatgatgt caggtagcag ccttcgcccc agtgttctgc     2760

atggattcag catgtccaac atggtaattc acttcagttt aatgtctcct ttgctcttgc     2820

caaaaaatag cacacttttc cacattccag tgatgtgtga gctatgcaaa caaaatccaa     2880

gattctgctg gtgaataact atgccagcaa ccttgtaagc tatctgtgca ggatatttgc     2940

actatttcca catggaatca atctttaaca acctctgagc cttggtgtac agaccacctt     3000

tcacaaaacg aaatgctatg actgtatctt gatatctcga actttcaaaa tatattttca     3060

gtacacccag ttgccaaagt tttgctgtct cttagagaaa gaactatgaa atcaactgac     3120

aagaaacaca ttcttattga caattgtgta taactggatt gcagactgtt cttactgtaa     3180

ctacttcctg attaggaata tgaccatttg actgttcaat gattatttgt atttacagtt     3240

tccagagttt gtcattataa taggaacaat ctttgctgta tacttttaaa aaatactctg     3300

ctatttctct tgctggaact gttgaaagaa aatatataga atgatctatt gctcatcagc     3360

tttatttttt aaacatacga cttattttgt tgaaattgtc aaagactgta tttagatctc     3420

ataatgcttt gttaaatgtt tacaagtaaa tagtttgaat tcagtaaata ttattggttg     3480

ttgtattgat caatgcatgt tacccattca accattttat agactaccaa tttcttttat     3540

gttaactaga atgcttttgt taaaagttat ttgttcatta tttgtgctac ccctttgatt     3600

atgcagacaa cctcatcagc tgcctaactt atccatcttt gaacttctga ctacttgttg     3660

tatctgctgg atatttagtt caactgtata gttttattta cttctgtatg tgtatttttg     3720

tgaagtattc acaaaggtta agttaaaata aaaccaaggg atatcttgca taattgatta     3780

aaaaaaaaaa aaaaaa                                                     3796


<210>  2171
<211>  6897
<212>  DNA
<213>  homo sapiens

<400>  2171
gtccggcggc gtcgcgggcg gcgggcggcg gggccgcggg aggggcgcgg gggcagacaa       60

agccgcggta atgaatggag cgtccgcccg cgccgccgtc gtccgcagcc ggccgggagc      120

cgccccagag gccgggccga ggtaatgcac aagggtcacg tgtatgctct caagatgatc      180

aggcagatcc tgtcctcagg accagaagca cgtctctgct gcacacattg ttgtctacac      240

catgagtgtt tagtagcagg actcttggaa agcagtgatc tatgctgtaa gaccatgagt      300

cacagattct ttttttcagt actatttatg attagccata tttctagaaa catcctgaaa      360

gatggaatta tgacgaaaaa gtgaagataa tctacattcg ggggcacaaa tgagcacttg      420

gatcagtgtt ttatgaacct aagatacagc cggagtagtt atggtcagtc atggagaata      480

acttgaaaac ttgtcccaaa gaggacggtg atttcgtttc tgataaaata aagtttaaaa      540

tagaagagga agatgatgat ggaattcctc ctgatagttt ggaaagaatg gactttaaaa      600

gcgagcagga ggacatgaag cagacagaca gcggtgggga gcgagcgggc ctcggtggga      660

cgggttgcag ctgcaagccc ccggggaagt acttgtctgc agagagtgag gatgactatg      720

gcgcgctgtt ctcccagtac agcagcaccc tatacgacgt ggccatggag gccgtgaccc      780

agagcctcct ttccagccgg aacatgagct ccaggaagaa gtctccagcc tggaagcatt      840

tttttatctc tccccgagac agcactaaag caatatgcat gtactgtgtg aaggagttca      900

gcagaggcaa aaacgagaaa gacttgagta ccagttgtct catgaggcac gtgaggcgcg      960

cacacccgac cgtgctcatt caggaaaatg gcagtgtgtc tgccgtgtcc tcgttcccct     1020

ctccctcact cctgcttcca ccacagcctg cggacgcggg tgacctcagc accatcctct     1080

cacccatcaa acttgtccag aaagtggcgt ctaagatccc gtcccccgat cgaataacag     1140

aggagtctgt gtctgtagtt tcttctgaag aaatctcctc tgacatgtcc gtttcggaga     1200

agtgcggcag agaagaagcc ctggtggggt cgtctcccca cctccctgct ctccattacg     1260

atgaacctgc agagaactta gcggagaaga gccttccact tccaaagagc acctctgggt     1320

ccaggagaag gtccgctgtc tggaagcact tctacctgtc gccactggac aactccaaag     1380

ctgtctgcat tcactgcatg aacgagttca gccgggggaa gaatgggaag gacctgggca     1440

cgagctgcct catcaggcac atgtggaggg cacaccgcgc catcgtgttg caggagaacg     1500

ggggcacggg catcccgcca ctgtactcca cccctcccac tctgctgcct tccttgctgc     1560

cgccggaggg ggagctcagc tctgtgtcct cgtctccagt aaagccggtc agagagtccc     1620

cttcggcctc ctcctcccct gacaggctga ctgaggactt gcagtctcac ttgaaccctg     1680

gagatgggct gatggaagac gtggcggcct tctcatcttc cgatgacata ggggaggcct     1740

cggcgtcctc tcctgagaag cagcaggctg atgggctgag tcctagattg tttgaatctg     1800

gcgccatctt ccagcagaat aaaaaggtca tgaaaagact gaagtcggag gtctggcatc     1860

acttctccct ggcccccatg gacagcctca aggccgagtg tcggtactgc ggctgtgcca     1920

tcagccgggg gaagaagggt gatgtgggca ccagctgcct gatgagacat ctctaccggc     1980

gccatccaga agttgtcggg agccagaagg gcttcctggg tgcaagtctg gcaaactctc     2040

cgtatgccac tttggcctct gcagaaagtt cctcttccaa attgactgac ttgccaacag     2100

tggtcacaaa aaacaatcaa gttatgtttc ctgttaatag caaaaagacc tcgaagctgt     2160

ggaatcattt ttctatttgc tccgcagact ccacaaaagt cgtgtgcttg cactgtggcc     2220

ggaccatcag ccgggggaag aagccgacta acttgggtac cagctgtctt ctgagacatt     2280

tacagcggtt ccatagcaac gtgctgaaaa ctgaggtctc ggagacggct cggccctcct     2340

ctccggacac ccgggtgccg cggggcacag aattatcagg cgcttcctct tttgatgaca     2400

ccaatgagaa gttttacgat tctcacccag ttgccaaaaa aatcacaagt ctcatagctg     2460

aaatgattgc acttgacctc cagccatatt cttttgtaga caacgttggc tttaacaggc     2520

tgcttgaata cttgaaacct cagtactccc tccccgcccc ttcctacttc tccaggacag     2580

ctatcccagg tatgtatgat aatgtgaagc agataattat gtcccacctt aaggaagctg     2640

agagtggtgt gatccacttc acgtctggaa tatggatgag taaccagacc cgtgagtacc     2700

tgaccctcac ggcccactgg gtttccttcg agtcgccagc ccggccgcgc tgtgacgacc     2760

accactgctc ggcgctgttg gacgtgtcgc aggtggactg cgactacagt ggcaacagca     2820

ttcagaagca gctggagtgc tggtgggaag cgtgggtgac ctccaccggc cttcaggtgg     2880

gcatcaccgt caccgacaac gccagcatcg ggaagacgct gaacgagggg gagcactcga     2940

gcgtgcagtg cttcagccat acggtgaacc tgatcgtcag cgaggccatt aagagccagc     3000

ggatggtgca gaacctgctg agcctcgccc ggaagatctg cgagcgggtg caccggtcgc     3060

ccaaggcgaa ggagaaactg gccgagctgc agagggagta cgcgctgcct cagcatcacc     3120

tcatccagga cgtcccgtcc aagtggagca cttccttcca catgctcgag cggctcattg     3180

agcagaaaag ggccattaac gagatgtccg tcgagtgtaa cttccgagag ctgatcagct     3240

gcgaccagtg ggaggtcatg cagtccgtgt gccgtgcgct aaagcccttc gaggctgcga     3300

gccgggagat gagcacgcag atgtccaccc tcagccaggt catccccatg gtacacatcc     3360

tcaacaggaa ggtggagatg ctcttcgagg agacgatggg catcgacacc atgctgcgct     3420

ctctgaagga ggccatggtg agccgcctgt ctgccaccct ccacgacccg cggtacgtct     3480

tcgccacgct gctggatcct cgctacaagg cctccctgtt tacggaggag gaggcggagc     3540

agtacaaaca ggatttaatc agggaactcg aactcatgaa ttctacctca gaggacgtgg     3600

ctgcctccca caggtgtgat gctggctccc cgtcgaaaga ctctgccgca gaggagaacc     3660

tgtggtcact tgtggccaag gtgaagaaga aagacccaag agaaaagctg cctgaagcca     3720

tggtgcttgc gtatctggag gaggaggtgc ttgaacacag ctgtgacccg ctcacctact     3780

ggaacctgaa gaaggcgtcc tggccggggc tgtccgcgct ggccgtcaga tttttgggct     3840

gccccccaag catcgtccct tcagaaaagc tgttcaacac acccactgag aacggtagcc     3900

ttggccaatc caggctcatg atggaacatt ttgaaaaact tatctttttg aaagtgaatc     3960

ttcccttaat atactttcag tattgaaact cacgacggca ccactaggcc agaggcgtgg     4020

ctgccccagc gttagcagcc tgtaccaggt ctatgacccg ctctgcccac ggctgtgtac     4080

gacatcagac caggcactct cagggccgct ctccagctca ccacagtgtc tccacgtgcc     4140

ttaccccttc tccttcaggc caagtttcgc ggggtgtttt attaagacgt ccactagaaa     4200

tagcttgtcc tgtcaactat gaaatatggt gactagattt taattcataa ccgtaaagtt     4260

ttttaaagtt ttgggttagt aatttgtttt actagaatga caaagaagat gtaaaccatt     4320

ttattctgta ggctttttac tcaattatgt acaaaccaca aatcaggtac tgtattttag     4380

tgaagcattg ctttaattgc aacagaatag cttttgtggc tatcaaatga aatctgtaaa     4440

taggaggtgg agggcaagcc atcctgactg agcagttttt aaccgcaggt tctaaagtgt     4500

cccgcggagt acagataata ttctggaagg taactgttta ctacgacaga gacgtggcat     4560

ttggaaacga aacttagatg tttcatggag cttattttga gaactttccc atttcaggtt     4620

tctgcattca ggctttacat ggtcagttaa ctcagagata ccccagctgt ttatcatcag     4680

ctcctctgaa atgtgatccc tttgtaactg tgctcatcac ttcgccagtg cgttcaatga     4740

cacgctgatg gcaggtggtc cctgctgaaa cccccacgcc tccgcttcag catctccacg     4800

ctctgaagct gtctttcaaa atgtgtgcac tgaccccctt gtttgatcaa atttgtgtaa     4860

aattttttta gaagagatgg cttattaaca gggaagaagc ttgttatatt ccagttgtaa     4920

gaatagcctt agtgtttaga tttttttatg atagggaaga tgcggccatc actgggatat     4980

tttcaaatcc caaggacatc agagtgaagt gtcagttgtc agatgatttt aaaagttatg     5040

tcttcagaga aaaaaagatt cattttctca ttttaaacca attaaatatt ctgagtgaga     5100

ctaatcactc atttgcctac gaccttttag aaaagttgtt ttgttgaaat actgtacgta     5160

cgcttaatct aaatttgcat tgactatgtt ttagtgtatt tataaatggt gaactcagtt     5220

tctgaaatta aacttcttat ttgcaatttt ctagtgctgg cagacactgg ctttttattt     5280

ttaggataag aaaacaggca tattctttgt ggtccattat ctagagccca tacttgggca     5340

gcatttgaaa tttcacctta accccagaca gggctccagg gaagtggaga tgtaattctt     5400

acaacaacag ttctgatcat ggccatggtg atgactttcc aggtctcgtg ttcaagtggt     5460

gccagaatgc aggagccggt gggcagccct gaggggttgc cttggccgca gcctctgtgc     5520

acgctcttcc tggtgtcctc ttacccggta gctgtgcgct tgttcccgtg agaacagcct     5580

gcttccagag tgcccaggag tgctggtcag ggacagtgcc cgtgaggctg cagaggaggt     5640

ggggtccatg gcccacccat ctctccctcg ccagcagccc tggccagtgt catcctggtg     5700

tagaaagggt tgcgcacagg ataggaggga gccacagttc ttgcttagct gtgctcacga     5760

ccagcttgca gtcctgtgtt tcttaagatt gtatttggaa tggtaatatc cttagaattt     5820

tgggatattg agcttcatgg attttctctc caaaacaagc cagcacaact aactgtagca     5880

gaattgtatc cactcattca ttcaactgag atgaagtgcc ctcccttttc cagggcctgg     5940

gctagttcct ggaatgcaac agagatttcc gtggacacag tctctagtct cacagagcat     6000

atagtctagt ccacgattgg caagctgcaa ccacagaccc agtccggcac tctgcccatt     6060

tttctaagtg aaattttctt ggaatacagt cacagctgtt tttttaacat ggtgtcttgg     6120

ctactttcag gctgcgacgg gagaactgaa tagttgtgac agagaccaca ggcccactga     6180

aagggacaaa cagggctgaa aatactcact gtttggccct ttccagaata gcaagtttgc     6240

tggcccttga gctagcctgc ctttatgggg ttttttttgt ttgttttttt aagctttcag     6300

cttcatgctg ctgtattttt agttgaagtg ttctgagtaa cagtcagtgt ataaaagggg     6360

attgcagaaa aaaatgaggg cttgctttac tcaacagaaa atatggccct tcctgaatga     6420

cactaggaga gtcattttat ctcatacatt cccttcattt cgttggtgga catttgttga     6480

aaccggcact caatggtcaa accgtctctg ccctccagtt gctgacagtc ctgcaggaag     6540

atggacaaga ggcccagtgc tgacagtcac acgactctca ctacttgaat gaggggactg     6600

tgggtgcaac tagaaaatat gttgattctt agccattccc accttgcctc tccgttcaga     6660

accccagctg cgagctgttt gtttccctgc ctggaaatga tgttttaggc aggttcctta     6720

atttctcagg tctgtctcag ataataaaaa gctctttgta tgagcctcag aactgtctct     6780

tcagtgaatg aaattaccag tcattatacg aagggacttt aaaaaatttg tggaaatact     6840

gaagtaaaag atgataaaaa aataaaaact ttatttcttg gctgggaaaa aaaaaaa        6897


<210>  2172
<211>  2417
<212>  DNA
<213>  homo sapiens

<400>  2172
gcagcagaga ggagttgagg gcgatgagag cgggtactgc gaactgccgg gcgatgctgt       60

cgctgccgcc gtgatacgga gagcaacagt tccccagcaa cacccctccc cgacacaggc      120

acacaccccc cgacaggcac gcacacccac cccacagtgc ccggctcggc tgcgcctcct      180

ctattggccc aggaagccca cccagccccg ccacgcagag cccagaagga aagaaagcct      240

catgcctgag ccgaggggag caccatggat ctgacaaaaa tgggcatgat ccagctgcag      300

aaccctagcc accccacggg gctactgtgc aaggccaacc agatgcggct ggccgggact      360

ttgtgcgatg tggtcatcat ggtggacagc caggagttcc acgcccaccg gacggtgctg      420

gcctgcacca gcaagatgtt tgagatcctc ttccaccgca atagtcaaca ctatactttg      480

gacttcctct cgccaaagac cttccagcag attctggagt atgcatatac agccacgctg      540

caagccaagg cggaggacct ggatgacctg ctgtatgcgg ccgagatcct ggagatcgag      600

tacctggagg aacagtgcct gaagatgctg gagaccatcc aggcctcaga cgacaatgac      660

acggaggcca ccatggccga tggcggggcc gaggaagaag aggaccgcaa ggctcggtac      720

ctcaagaaca tcttcatctc gaagcattcc agcgaggaga gtgggtatgc cagtgtggct      780

ggacagagcc tccctgggcc catggtggac cagagccctt cagtctccac ttcatttggt      840

ctttcagcca tgagtcccac caaggctgca gtggacagtt tgatgaccat aggacagtct      900

ctcctgcagg gaactcttca gccacctgca gggcccgagg agccaactct ggctgggggt      960

gggcggcacc ctggggtggc tgaggtgaag acggagatga tgcaggtgga tgaggtgccc     1020

agccaggaca gccctggggc agccgagtcc agcatctcag gagggatggg ggacaaggtt     1080

gaggaaagag gcaaagaggg gcctgggacc ccgactcgaa gcagcgtcat caccagtgct     1140

agggagctac actatgggcg agaggagagt gccgagcagg tgccaccccc agctgaggct     1200

ggccaggccc ccactggccg acctgagcac ccagcacccc cgcctgagaa gcatctgggc     1260

atctactccg tgttgcccaa ccacaaggct gacgctgtat tgagcatgcc gtcttccgtg     1320

acctctggcc tccacgtgca gcctgccctg gctgtctcca tggacttcag cacctatggg     1380

gggctgctgc cccagggctt catccagagg gagctgttca gcaagctggg ggagctggct     1440

gtgggcatga agtcagagag ccggaccatc ggagagcagt gcagcgtgtg tggggtcgag     1500

cttcctgata acgaggctgt ggagcagcac aggaagctgc acagtgggat gaagacgtac     1560

gggtgcgagc tctgcgggaa gcggttcctg gatagtttgc ggctgagaat gcacttactg     1620

gctcattcag cgggtgccaa agcctttgtc tgtgatcagt gcggtgcaca gttttcgaag     1680

gaggatgccc tggagacaca caggcagacc catactggca ctgacatggc cgtcttctgt     1740

ctgctgtgtg ggaagcgctt ccaggcgcag agcgcactgc agcagcacat ggaggtccac     1800

gcgggcgtgc gcagctacat ctgcagtgag tgcaaccgca ccttccccag ccacacggct     1860

ctcaaacgcc acctgcgctc acatacaggc gaccacccct acgagtgtga gttctgtggc     1920

agctgcttcc gggatgagag cacactcaag agccacaaac gcatccacac gggtgagaaa     1980

ccctacgagt gcaatggctg tggcaagaag ttcagcctca agcatcagct ggagacgcac     2040

tatagggtgc acacaggtga gaagcccttt gagtgtaagc tctgccacca gcgctcccgg     2100

gactactcgg ccatgatcaa gcacctgaga acgcacaacg gcgcctcgcc ctaccagtgc     2160

accatctgca cagagtactg ccccagcctc tcctccatgc agaagcacat gaagggccac     2220

aagcccgagg agatcccgcc cgactggagg atagagaaga cgtacctcta cctgtgctat     2280

gtgtgaaggg aggcccgcgg cggtggagcc gagcggggag ccaggaaaga agagttggag     2340

tgagatgaag gaaggactat gacaaataaa aaaggaaaag aaaaaaaaaa acagaaggaa     2400

aaggaaaaaa aaaaaaa                                                    2417


<210>  2173
<211>  2469
<212>  DNA
<213>  homo sapiens

<400>  2173
gaaacaaagg gaaacggggg gcggtgtggc ggggcggggg gtggagagct gaggccgagc       60

gaaggaaatg caccaatcag ctgctccccc gggctcacaa ctgtctgctg cgcccgaaaa      120

acaagtcggt gcgctgggga cccggggccg gggccgcctt actccggcct agccccgcgg      180

ccctcggtgc gggctccagg gcatgctcgg gaccccccgc ggctccagcc cagacgcccc      240

ggcctcaggt ctcggccccc gcttggggcc ccggccgtgc ggccggaggg agcggccgga      300

tggagcggag gatgaaagcc ggatacttgg accagcaagt gccctacacc ttcagcagca      360

aatcgcccgg aaatgggagc ttgcgcgaag cgctgatcgg cccgctgggg aagctcatgg      420

acccgggctc cctgccgccc ctcgactctg aagatctctt ccaggatcta agtcacttcc      480

aggagacgtg gctcgctgaa gctcaggtac cagacagtga tgagcagttt gttcctgatt      540

tccattcaga aaacctagct ttccacagcc ccaccaccag gatcaagaag gagccccaga      600

gtccccgcac agacccggcc ctgtcctgca gcaggaagcc gccactcccc taccaccatg      660

gcgagcagtg cctttactcc agtgcctatg acccccccag acaaatcgcc atcaagtccc      720

ctgcccctgg tgcccttgga cagtcgcccc tacagccctt tccccgggca gagcaacgga      780

atttcctgag atcctctggc acctcccagc cccaccctgg ccatgggtac ctcggggaac      840

atagctccgt cttccagcag cccctggaca tttgccactc cttcacatct cagggagggg      900

gccgggaacc cctcccagcc ccctaccaac accagctgtc ggagccctgc ccaccctatc      960

cccagcagag ctttaagcaa gaataccatg atcccctgta tgaacaggcg ggccagccag     1020

ccgtggacca gggtggggtc aatgggcaca ggtacccagg ggcgggggtg gtgatcaaac     1080

aggaacagac ggacttcgcc tacgactcag atgtcaccgg gtgcgcatca atgtacctcc     1140

acacagaggg cttctctggg ccctctccag gtgacggggc catgggctat ggctatgaga     1200

aacctctgcg accattccca gatgatgtct gcgttgtccc tgagaaattt gaaggagaca     1260

tcaagcagga aggggtcggt gcatttcgag aggggccgcc ctaccagcgc cggggtgccc     1320

tgcagctgtg gcaatttctg gtggccttgc tggatgaccc aacaaatgcc catttcattg     1380

cctggacggg ccggggaatg gagttcaagc tcattgagcc tgaggaggtc gccaggctct     1440

ggggcatcca gaagaaccgg ccagccatga attacgacaa gctgagccgc tcgctccgat     1500

actattatga gaaaggcatc atgcagaagg tggctggtga gcgttacgtg tacaagtttg     1560

tgtgtgagcc cgaggccctc ttctctttgg ccttcccgga caatcagcgt ccagctctca     1620

aggctgagtt tgaccggcct gtcagtgagg aggacacagt ccctttgtcc cacttggatg     1680

agagccccgc ctacctccca gagctggctg gccccgccca gccatttggc cccaagggtg     1740

gctactctta ctagccccca gcggctgttc cccctgccgc aggtgggtgc tgccctgtgt     1800

acatataaat gaatctggtg ttggggaaac cttcatctga aacccacaga tgtctctggg     1860

gcagatcccc actgtcctac cagttgccct agcccagact ctgagctgct caccggagtc     1920

attgggaagg aaaagtggag aaatggcaag tctagagtct cagaaactcc cctgggggtt     1980

tcacctgggc cctggaggaa ttcagctcag cttcttccta ggtccaagcc ccccacacct     2040

tttccccaac cacagagaac aagagtttgt tctgttctgg gggacagaga aggcgcttcc     2100

caacttcata ctggcaggag ggtgaggagg ttcactgagc tccccagatc tcccactgcg     2160

gggagacaga agcctggact ctgccccacg ctgtggccct ggagggtccc ggtttgtcag     2220

ttcttggtgc tctgtgttcc cagaggcagg cggaggttga agaaaggaac ctgggatgag     2280

gggtgctggg tataagcaga gagggatggg ttcctgctcc aagggaccct ttgcctttct     2340

tctgcccttt cctaggccca ggcctgggtt tgtacttcca cctccaccac atctgccaga     2400

ccttaataaa ggcccccact tctcccatta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaa                                                             2469


<210>  2174
<211>  5820
<212>  DNA
<213>  homo sapiens

<400>  2174
ccccgcgcgc ctcgctggga gcacccgggc cgaggctctg attctggggg gaggccgact       60

ccaccctggc tggaggaact gggtgctcct gcccgctggc ccctcgcgcg tgaggatcta      120

tctcaggcta agaaatggca tttcaaaagg cagtgaaagg gacgattctt gttggaggag      180

gtgctcttgc aactgtttta ggactttctc agtttgctca ttacagaagg aaacaaatga      240

acctggccta tgttaaagca gcagactgca tttcagaacc agttaacagg gagcctcctt      300

ccagagaagc tcagctactg actttgcaaa acacatctga atttgatatc cttgttattg      360

gaggaggagc aacaggaagt ggctgtgcgc tagatgctgt caccagagga ctaaaaacag      420

cccttgtaga aagagatgat ttctcatcag ggaccagcag cagaagcact aaattgatcc      480

atggtggtgt gagatatctg cagaaggcca tcatgaagtt ggatattgag cagtatagga      540

tggtaaaaga agcccttcat gagcgtgcca acctgctaga aattgctccc catttatcag      600

ctccattgcc tataatgctt ccagtttaca agtggtggca gttaccttac tactgggtag      660

gaatcaagct gtatgatttg gttgcaggaa gcaattgcct aaaaagcagt tatgtcctca      720

gcaaatcaag agcccttgaa catttcccaa tgctccagaa ggacaaactg gtaggagcaa      780

ttgtctacta tgacggacaa cataacgatg cacggatgaa ccttgccatt gctctgactg      840

ctgccaggta tggggctgcc acagccaatt acatggaggt agtgagcttg ctcaagaaga      900

cagaccccca gacagggaaa gtgcgtgtga gcggcgcacg gtgcaaggat gtcctcacag      960

ggcaggaatt tgacgtgaga gccaaatgtg ttatcaatgc cacgggacct ttcacggact     1020

ctgtgcgcaa aatggatgat aaagacgcag cagctatctg ccagccaagt gctggtgtcc     1080

atattgtgat gcctggttat tacagcccag agagcatggg acttcttgac ccagcgacca     1140

gtgatgggcg agttattttc ttcttaccct ggcaaaagat gacgatcgct ggcactactg     1200

atactccaac tgatgttaca caccatccaa ttccttcaga agaagatatc aacttcattt     1260

tgaatgaagt gcgtaattac ctgagttgtg atgttgaagt gagaagaggg gatgtcctgg     1320

cagcatggag tggaatccgt cctcttgtta cagaccccaa atctgcagat actcagtcta     1380

tctcccgaaa tcatgttgtt gatatcagtg agagtggcct tattactata gcaggtggaa     1440

agtggacaac ttatcggtct atggcagaag ataccataaa tgctgctgtc aaaactcata     1500

atttaaaagc aggaccaagt agaacagttg ggcttttcct tcaagggggt aaagattgga     1560

gccccacact ctacattagg cttgtgcagg attatggact tgaaagcgag gtggcacagc     1620

atcttgccgc cacctatggt gataaggcct ttgaggtggc caaaatggca agtgtgactg     1680

gcaaaaggtg gcctattgtt ggagtacgtc ttgtgtcaga atttccatat attgaagcag     1740

aggtgaaata tgggattaag gagtatgcct gcactgctgt ggatatgatt tcacgtcgta     1800

ctcgcctggc ctttctaaat gtccaggcag cagaggaagc cctacccagg attgttgaac     1860

tgatgggcag ggaactgaat tgggatgatt ataagaagca ggaacaactt gaaacagcca     1920

ggaagtttct atattatgaa atgggctata aatctcgatc agaacagtta acagatcgct     1980

ctgaaattag cctactgcct tcagacattg acaggtataa gaagagattt cataagtttg     2040

atgcagacca gaaaggcttt attaccattg ttgatgttca gcgtgtatta gagagtatca     2100

atgtccaaat ggatgaaaat acactccatg aaattctaaa tgaagttgat ttgaataaaa     2160

atggacaggt tgaactcaat gaatttttgc agctgatgag tgctattcaa aaaggaaggg     2220

tatctggaag ccggcttgct atactaatga aaactgcaga agagaacctc gacagaagag     2280

ttccaattcc agtggaccgt agttgtggag gattgtgagt ctgggcagta aatccacagc     2340

caacaaacat agaaacgaca aatcaccatg taacaaccag agatgactga aaccactctg     2400

aaataatgaa tgtggatagc tgcctttttt aacactagaa aacattccaa aactttaagg     2460

tgttggtgta tttgccagct ttatttgctg tactttattt gtatttgcca ttcagtctag     2520

cttttaagta tatttttttc tttttctcat tttcaatgca cattagtttt gcatctgttt     2580

tgtgacctgt tagatgtgac acattctctt tttgtttatt cccttattct aaatgagttc     2640

taaaaacata atattttggc aaaaattgaa aaaagctgga gacattttgt gacatgcata     2700

cagatagcat gtgttattaa aaagagttgc ctattgaaat gatcgtgttt ctggagaaat     2760

taagcttata gacagcatgt gttattaaaa agagttacct attgaaatga tagtgtttct     2820

ggagatttct cagccccatc ttcctccagc ttgtctacct tcctcatgca aacaatattc     2880

cacattttta tatctagagc atgactggct aactggagag ggaaggaaaa gtttagatct     2940

ggttactgga gcaagtctca aagagaaact ctgaaagctt ccagaatcac aggtataaga     3000

taaggatagc attgacattt gctgggagtt acagtgatag tttcatctca gcagttcatt     3060

tttttcttca gtcactgctg gttttctttg actattatag ttgccaggaa gatccttgct     3120

cttcttactt taaaaccagc atttaagtgg caatttggat gtaataggat gagaccaaat     3180

ttatctaatt attacagtag taatacattt aagagttaaa aatgtgtttt tatatatcca     3240

catatgataa caaaagattc aattcccaag cctaaatttt gaagcatgtg gtattgtcaa     3300

atctagctta ccatcttttt tgggggtact tgcaaccata gtaaaggaag atggaataga     3360

ctttagttaa ctttaattat aattatatgt taaataaggc acataaccag tttccaaggt     3420

catcatggtt gcttaaagtc tttccccttc tgtactccat ggaaatattc tcagtaaacc     3480

aaaaacaaaa atggaaaaat aatcaccaac ccccatcccg acacacacac agagtccaaa     3540

gcaaaagtca gtgtgtattg aatttaacaa gtaatgcagt ttgggatgct tttgctacat     3600

tttggtggca ttttaactag ttatctgaat atttattaat cgtacttcct cttgtaaagt     3660

taactactta cttttttgtt gttgtttttt taacatcagg ttctgtatct aataggagat     3720

gtaacacttt atttcatggc aggtttttat tgcagagact tgaagtctta gttttttaaa     3780

ctggcacata aaacactttt tgctgttatt tttatttatg tcaatactgc agagtatctt     3840

tatgccttat tcaagtggat tctgagcctg tatgtcacaa tgtaaacact ggaggttcac     3900

tcacctacgc actcacccac cacctctgaa agaaacagaa actgcagaga aagacagcat     3960

cttagctcat tttgttttta aatgaggttt tagacgcttg ccacttccta agggaaatcc     4020

taaaacagag caagtgatgc tcccaggtat cactgtgaac ttttttcttt caaagtgtga     4080

atttttacac tggctttttc atttttttaa agtaattgaa gcttgtggct ttacaactta     4140

gtgttttttg ctatccagat aacaagtttc attgtttaga acccagtgac acttaatagg     4200

tagataaatt gtcctttaaa atatcccaga tgatatacac aatatggtac atttgtgctc     4260

tctctctctg tttttctctc tttctctttc tagttagatc aagataacga tgacttgtac     4320

cctccctgat tctgttacag tagggcccgg gcagatctgt gtttgttaaa caggccttgt     4380

ttgtgcatgc tttgctatga atgaagttcc tttaaggaca aagaaaagca cacttttctt     4440

cttttgagca tatctgcttt tactttaaat ctgctaattt ctaaaatgta gagtccttca     4500

ccaatcccag agactcaatt tggaaatgaa ctgatttcaa gccgttactg tgaataaagc     4560

accccagcat tttgtataag ctcttaatta aacctgtaca gcttctttac ctgatttaag     4620

aaagggagac aagcaatagg ggggaataag cttcttcaaa attcattcca agcacaaaag     4680

aaattttttc cctttgcata taaacttgac atcagttgat tctgttgggg tcggggtggg     4740

tatgcaggga ttgcctttta ttatcaagtg atttatttca agagcctttg aggggattca     4800

ggtgaaggaa cccccatctg tgctggagag ttggatactc ctttaaatag cccccaccac     4860

agtcataaca ataatgataa tgctggatta tttgttaagc caaggttgtc tgcctcatat     4920

ccatcatgct gtttgcaata ttcttgcttt caatcaattt atactgagtg taactttagg     4980

atttctgcta ttaaatgcat gctctctatc ctgcttcagt ttctggcttt gctttgtctg     5040

tttcaaaata tgtagcttcc tcttttgtac aacaaaaaac tcattctcac ttttactaaa     5100

tatactgtag gagtcatcat tgatgttatt tttctcttat gtatctgtaa agatttttgg     5160

catatgaatg taatattaaa gtcaatgatg ctataacttg cgatgtttgc atcatgtcaa     5220

cctttttgaa ggagtgaaaa agccctacta tgtttttaaa tagcaagtgt aagctcagtg     5280

ctagagtgga tatacacacc gcatgttttc atatgtggca cttttatgta tcatgttggg     5340

ttattgttct agactggact gttaaatact atgtttgagg ctgggttgtc atttttataa     5400

ctgtcttggt gttttatggc cattatttat tacttttgat acacagaatg agctgcatgc     5460

atttatagag caataagagg atgtatttaa tgtgccttgt ttttaactga ataagaactg     5520

gaagcatgaa tcaataaaac tgattaaaat ggtctatttg ctagcatttt gatgttactt     5580

gcagtcagat aactttgatt actgttgaag tttaaaaaaa gtttgaaaat atttttacaa     5640

actgtgtttt tgatgacaca aaagtgaaat atctacagag atagatgtaa ttttataaga     5700

ctgccagaat tatttgtatt aatttgttgc tgtagccttt agggcatgac ttctgtattt     5760

gtgcaatcct attctacaat tacattcatc ctattacaac tcaaaaaaaa aaaaaaaaaa     5820


<210>  2175
<211>  7554
<212>  DNA
<213>  homo sapiens

<400>  2175
ggggcctcgc ggccggcgag gggctgagct gacagggccg catcggctta ccccacctta       60

ctttatcgga acgtgcctaa gctgctgcag ctggcacccg gttgcgctcg gcgaagaggg      120

ctgggggcgg gagatgacgg tggtcttctc cctgcttggc accctgcgag caccagctcc      180

cttctcctcg ccactccaag gttgcagacg aagcaggtac tgtcctagat gttaaggaca      240

caacattgag caaaaacatg catagtccct gcttccgtga cacttgagtg aactgaatgt      300

gcaaagtccc tgtggcacaa agtccctggg gccagtgtgt gtggcgggtg tagaaggagc      360

taaagagatc tggttggagt tggagggtga gagaaaatga attctaattt acctgcagag      420

aacttaacca ttgcagtcaa tatgaccaag actttgccta cagcagtaac gcatggattt      480

aattccacta atgacccacc ttcaatgtca attacaaggc tttttccagc cttactggaa      540

tgctttggca ttgtcctttg tggctacata gcaggaaggg ccaatgtcat aacatcaacc      600

caggccaaag gactaggaaa ttttgtctcc agatttgcac ttccagcttt attattcaaa      660

aacatggttg tacttaattt ttccaatgtg gactggtcct tcctatatag tatcttaatt      720

gccaaagctt ctgtattttt cattgtatgt gtattaacct tattggttgc cagtcctgat      780

agtcgattta gcaaagctgg actattccct atttttgcta cacaaagtaa tgactttgca      840

ttgggatacc ctatagttga agctttatat caaactacat acccagaata tctccagtac      900

atttatttgg tggcaccaat atctcttatg atgttaaacc ctatagggtt tattttctgt      960

gaaatccaaa agtggaaaga cactcaaaat gcttctcaaa ataaaataaa aattgtggga     1020

ctcggactcc tgcgtgtatt acagaaccca atagtattta tggtcttcat tggcatcgcc     1080

ttcaatttta ttcttgatcg aaaggtacct gtatatgtcg aaaattttct tgatggactt     1140

ggaaattctt tttctggatc agccctattt tatcttggtc tcacgatggt gggaaaaata     1200

aagagactga agaagtcggc atttgtagta ctaattcttc tcatcacagc taaacttctg     1260

gtgctgccac ttctgtgcag agaaatggtg gaactcttgg acaagggcga cagtgtggtg     1320

aaccatacaa gtttatcaaa ttatgcattt ctgtatggtg tatttcctgt agcaccagga     1380

gtggctatct ttgcaacaca attcaacatg gaagtagaaa ttataacctc agggatggtg     1440

ataagcacat ttgtgtctgc tcccatcatg tacgtttctg cctggttact gacctttccc     1500

actatggacc ctaagccatt ggcatatgcc atccagaatg ttagttttga tataagtatt     1560

gtcagcctga tctccttgat ctggtctctg gctattcttc ttttgagtaa gaaatataaa     1620

cagcttcctc atatgcttac aactaattta ctcattgctc agtctattgt ctgtgctgga     1680

atgatgatat ggaattttgt taaagaaaaa aattttgttg gacaaatttt ggtgtttgtt     1740

ctattgtaca gctccctcta tagcacctac ctgtggacag gccttctagc aatttctttg     1800

tttcttttga aaaagcgaga gagggtacaa attcctgttg gaataatcat aatatctggc     1860

tggggaattc ctgctctcct tgttggtgtt cttttgataa ctggaaaaca caatggagat     1920

agcattgact cagccttctt ttatggaaaa gaacagatga tcaccacagc agtcaccctg     1980

ttctgcagca tcctgatagc tggcatatcc ctcatgtgca tgaaccagac tgcccaagca     2040

ggaagctatg aaggtttcga tcagtctcag agccacaaag tggtggagcc tggaaatact     2100

gcttttgagg agagtccagc accagtaaat gaaccagaac tttttacaag ctctattcca     2160

gaaacaagtt gctgctcctg ctccatggga aatggtgaat tacactgccc atcaatagag     2220

ccaatagcaa acacaagcac cagtgagcct gtgattcctt cgtttgagaa aaacaatcat     2280

tgtgtgagtc gctgtaactc ccagagctgc atattagccc aggaagaaga acagtatcta     2340

cagagtggag accagcaact gacccgacat gtgttgctgt gtttacttct catcattggc     2400

ctgttcgcta atctttccag ttgtttatgg tggctattca accaagagcc tggaagactt     2460

tatgttgagt tacagttttt ctgtgccgtg tttaactttg gtcagggatt tatttccttt     2520

ggaatctttg gattagataa acatttaatc atcctgcctt tcaaaagaag acttgaattc     2580

ctatggaaca ataaagacac agcagaaaac agggattctc ctgtttcaga ggaaataaaa     2640

atgacctgtc aacaatttat ccattatcac cgtgacctct gtatccgaaa cattgtcaaa     2700

gaaagaaggt gtggtgcaaa gacttctgct ggaactttct gtggctgtga cctggtgagc     2760

tggctaattg aagtcggcct tgcctccgac cgtggtgaag ctgtgatata cggagacagg     2820

ctggtacaag ggggagtcat ccaacatatt accaacgagt atgaattccg ggatgagtac     2880

ttgttttaca gatttcttca aaagagtcct gaacagagtc ctcctgctat taatgcaaac     2940

actctccaac aggaaagata taaagaaatt gagcattcat ccccaccctc acattcccct     3000

aagacctaaa ttatgcaggg gagaacccta catggaatca tattctagcc gcgtattcat     3060

tagtttttag ctgggtgacc ttgggcaagt taacagaggc aacctctctg agcctcagtt     3120

gtctcttctg taaaatgtga aaagatgtgc tcccaccaca tgcgcagggt ctgtgatttt     3180

acatgtatgt aaaacacata ggaagctgac ttaggaaaaa gagaaaacca aattaaagtt     3240

ctgataatga atataatata gtcatccttt agtatccaag gggattggtt ccaggactcc     3300

tgaagatccc aaaatctgag gatactcaag tcccttatat aaaatggtgt aggccgggca     3360

tggtggctca cgcctgtaat cccagtactt tgggaggccg agtcaggtgg atcacctgag     3420

gtcaggagtt caagaccagc ctggccaaca tggcgaaacc ccgtctctac tataaaatac     3480

aaaaaattag ttgggtgtgg tggcgggtgc ctgtaatccc agctactcag gaggctgagg     3540

caggagaatc gcttgaatct gggaggcaga ggttgctgtg agccgagatc gtgccactgc     3600

actccagcct gagcaacaga gcaagactct atctcaaaaa taaaataaaa taaaataaaa     3660

taattaataa aatggtgtag tatttgcata taacctatgc acattctccc atatagttta     3720

atcatcttta gatacttata atgcctaata caatgtaaat gctatgtaaa tagttgttgt     3780

tatactgtat tgtttaggga ataacaataa gaaaaacagt ctgtacatgt tcactacaga     3840

tgcaaccatt gttaagcctg actacatctt tttatctgcg gttgattgaa tctatggatg     3900

tggaacctgt gcatatggag ggtcaactgt actataaata atacgaatat gccaacatta     3960

tataatcatt gctttctgca actgtttact ataatttcaa aattaatatc ctattaactg     4020

ttcctataaa ttatcaaatt tggcaagtgt attactagca ggagatggac cttaaattat     4080

gacaacttta tattttttga tagcatctct tgaaaaagaa ttttaatgat tctaataaga     4140

ggttcttttt cttttttcca tttccttgac aaatagtact catttaaaaa ctagagggct     4200

aggcttagtg gctcacgcct gtaatctcag cactttggga ggctgaggcg ggcagatcgc     4260

ttgaggtcag gagttcaaga ccagcccggg caacgtggtg aaacccggtc tgtactaaaa     4320

aaaaaaaaaa agaaaaagaa aaagaaaaaa gaatacccag gtgtggtagt gcatgcctgt     4380

agtcccagct actttggaga ctgaggtggg agtacccctt gagcctggga ggcgcaggtt     4440

gcagtgaacc aagatcacat cactgcactt caacctgggt gacagagcaa gaccctgtct     4500

caaaaacaaa aaacaagcaa aaaaaaccta gaggcactat ttttttttaa agtttgtctt     4560

ttcttttcta cccaaattac taatctatgc cattaaggaa aggaataaga acctccatat     4620

gtattattat ctccacagtc ctgcagaagt acaatctgat ctttaacttt catgctacaa     4680

ataataattt gagtagatta atttgaattt tatcaacaaa attattgcca tatgatgtat     4740

catttctgtg tttgaacaaa gcatcgtaat gcaggataac ttctacttta ttccctgtag     4800

ttaaaaaaaa aaaaactata tagttcaagc caatatttaa aaattctaaa cctaggctgg     4860

gcatggtgac tcatacctgt aatcccagca ctttgggagg ccgaggcagg tgaattgctt     4920

cagcccagga gttcgagacc agcctggcca atgtggtgaa accccatctc tactaaaaaa     4980

aaaaaaaaaa aaaaaaatta gccaggtgtg gtggtgtgca cctgtaatcc cagctaccca     5040

ggaggctgag gcaggaaaat tgcttgaaac caggaggcag aggttgcagt gagctgagat     5100

cgtgccactg cactccagcc tgagtgtcag agtgagactc tgtctcagaa aaaaaaaaaa     5160

aaattctaaa gattacattt agaatttagt ctttttaaag tgtccatgta taaaaatata     5220

taatttttaa aattactaaa tgttgccttt tctcttagtc taatatttta gctactaaaa     5280

caaaatataa actggatagc ttataaacaa cataaactta tttctcacag ttttggaggc     5340

tgtgaagtcc aagattaagg cactaacaga tctagtgtct ggtaaggcaa atttctggct     5400

catagatggt accttcttgc tgtgtcccca catggtagat gggaagaact ggtctcattg     5460

gccccttata aggacattaa ttccactcaa taggctccac cctcatgatc taataacctc     5520

tcaaaggccc tacctcctaa tactaacaca ttgaggatgt gacttcaact ttacatttct     5580

acaggcagag aagtggggct gtgtaaattc ttcccatcag tacttgaatg ttcatttaac     5640

aaataactta tcgagcatct agcatgttcc agacacaatc tgaacactga gcacacaaca     5700

gttggaacaa atatgattcc tatcctcatg gagcttctat tctcctgtga aaaacagatg     5760

ttaaacatga ttgaggatta ggtttcaaca taagaattct aggaggacac agacatttag     5820

accatagcat cttcaggtaa actttatctt cagtaaatta aagagatcta tttagatgac     5880

ctttgagcat cttaattatt agatgtcagt gctagtttaa cttattttaa acgtttcaga     5940

tatttattta attatacttt aagtgtctca tgtaaaaaag ttatttataa aataatttat     6000

agggttagag tcattgccct tttaatgcaa caaataaaca gttttttaaa aacctgcatg     6060

ggggccaggc gcggtggttc atacctgcaa tcccagcact ttgggaggtc gaggctggcg     6120

gatcacgagg tcaggagatc gagaccaccc tgattaatgc ggtgaaatcc cgtctctact     6180

aaaaatacaa aaaattagcc agacgtggtg gtgggcacct atagtcccag ctactcggga     6240

ggctgaggca ggagaatggc atgaacccgg aaggcggagc ttgcagtgaa ccaagatcgc     6300

gccactgcac tccagcctgg gcgacagagt gagactccat cgcaaaaaaa aaaaaaaaaa     6360

aacctgcatg gaagcctagt atatttatta ataacaaata aattatactt tagtgtacta     6420

ttaacctata ccaattttaa gttgtgatta gggaatgggg atgtttttaa gctgaattgt     6480

cttgctgcgg aactttcctt ttttaataag accatattat gactctgaat gctcaagggt     6540

aagtctaagg cctcattgct gttaccagga gatttttcta gttacagtaa taaagatgtt     6600

aattcacatg catgcagaca actgaaactc aagtggagaa tttgtttgtg aacaagtcat     6660

actacttctg ttatttgcat gaatggaatc tgcaatatct ttttccatgg gagaccctaa     6720

aagaaaaccc tggatcagaa tgatctgcag tttcagataa taaaggcttt taagagacat     6780

ttttagaatt aaaaatatgc taattttatt aaatgaaaat atttgtaact gttaactttc     6840

tcactgacaa agcaagtttc tcaataaaat acctatttta acttgcatta ctgacatctt     6900

ttctttgagt aatctgaata atgcagaagc catcatagag gtcttttcta tacattctca     6960

atgttttctt aaatgggttt cctgagttct gttcttcatg actctgggct ctgcaaacag     7020

ggtttcccaa ttacgcattc tataaacact tttatgaatg agtcaatatg acattgagtc     7080

cttttcatac atttcatcat ttccaatatg tagagtgaca gctagaaaaa tgataaaatt     7140

ttgattaaaa cctatctctt tttcttcagc atagtcaatt gttttcttaa ctctcaatga     7200

gtaactccat gcctagcttg tgcttagctt tcaatatttt tagactaaga caaagtgtat     7260

ttggcatttt gagaacaaca attaatggtc agtaaatttc taaagcaaga aaaatgtgaa     7320

actagtgttt tatatgtttg ttacgcagca gaatgcggct cttagtgttt gccccttcat     7380

atctcatcat gtaaaatatt aaattacttt aggccactgc acataggtag tcctgtcatg     7440

agtgatggct ggagaaaagt tcaggatcat aaatgttatc atcattcttc aagaaaagat     7500

gagattataa atttctgcaa ttggtatgat aaaaggttga aataattaat gaaa           7554


<210>  2176
<211>  7405
<212>  DNA
<213>  homo sapiens

<400>  2176
ggggcctcgc ggccggcgag gggctgagct gacagggccg catcggctta ccccacctta       60

ctttatcgga acgtgcctaa gctgctgcag ctggcacccg gttgcgctcg gcgaagaggg      120

ctgggggcgg gagatgacgg tggtcttctc cctgcttggc accctgcgag caccagctcc      180

cttctcctcg ccactccaag gttgcagacg aagcagagat ctggttggag ttggagggtg      240

agagaaaatg aattctaatt tacctgcaga gaacttaacc attgcagtca atatgaccaa      300

gactttgcct acagcagtaa cgcatggatt taattccact aatgacccac cttcaatgtc      360

aattacaagg ctttttccag ccttactgga atgctttggc attgtccttt gtggctacat      420

agcaggaagg gccaatgtca taacatcaac ccaggccaaa ggactaggaa attttgtctc      480

cagatttgca cttccagctt tattattcaa aaacatggtt gtacttaatt tttccaatgt      540

ggactggtcc ttcctatata gtatcttaat tgccaaagct tctgtatttt tcattgtatg      600

tgtattaacc ttattggttg ccagtcctga tagtcgattt agcaaagctg gactattccc      660

tatttttgct acacaaagta atgactttgc attgggatac cctatagttg aagctttata      720

tcaaactaca tacccagaat atctccagta catttatttg gtggcaccaa tatctcttat      780

gatgttaaac cctatagggt ttattttctg tgaaatccaa aagtggaaag acactcaaaa      840

tgcttctcaa aataaaataa aaattgtggg actcggactc ctgcgtgtat tacagaaccc      900

aatagtattt atggtcttca ttggcatcgc cttcaatttt attcttgatc gaaaggtacc      960

tgtatatgtc gaaaattttc ttgatggact tggaaattct ttttctggat cagccctatt     1020

ttatcttggt ctcacgatgg tgggaaaaat aaagagactg aagaagtcgg catttgtagt     1080

actaattctt ctcatcacag ctaaacttct ggtgctgcca cttctgtgca gagaaatggt     1140

ggaactcttg gacaagggcg acagtgtggt gaaccataca agtttatcaa attatgcatt     1200

tctgtatggt gtatttcctg tagcaccagg agtggctatc tttgcaacac aattcaacat     1260

ggaagtagaa attataacct cagggatggt gataagcaca tttgtgtctg ctcccatcat     1320

gtacgtttct gcctggttac tgacctttcc cactatggac cctaagccat tggcatatgc     1380

catccagaat gttagttttg atataagtat tgtcagcctg atctccttga tctggtctct     1440

ggctattctt cttttgagta agaaatataa acagcttcct catatgctta caactaattt     1500

actcattgct cagtctattg tctgtgctgg aatgatgata tggaattttg ttaaagaaaa     1560

aaattttgtt ggacaaattt tggtgtttgt tctattgtac agctccctct atagcaccta     1620

cctgtggaca ggccttctag caatttcttt gtttcttttg aaaaagcgag agagggtaca     1680

aattcctgtt ggaataatca taatatctgg ctggggaatt cctgctctcc ttgttggtgt     1740

tcttttgata actggaaaac acaatggaga tagcattgac tcagccttct tttatggaaa     1800

agaacagatg atcaccacag cagtcaccct gttctgcagc atcctgatag ctggcatatc     1860

cctcatgtgc atgaaccaga ctgcccaagc aggaagctat gaaggtttcg atcagtctca     1920

gagccacaaa gtggtggagc ctggaaatac tgcttttgag gagagtccag caccagtaaa     1980

tgaaccagaa ctttttacaa gctctattcc agaaacaagt tgctgctcct gctccatggg     2040

aaatggtgaa ttacactgcc catcaataga gccaatagca aacacaagca ccagtgagcc     2100

tgtgattcct tcgtttgaga aaaacaatca ttgtgtgagt cgctgtaact cccagagctg     2160

catattagcc caggaagaag aacagtatct acagagtgga gaccagcaac tgacccgaca     2220

tgtgttgctg tgtttacttc tcatcattgg cctgttcgct aatctttcca gttgtttatg     2280

gtggctattc aaccaagagc ctggaagact ttatgttgag ttacagtttt tctgtgccgt     2340

gtttaacttt ggtcagggat ttatttcctt tggaatcttt ggattagata aacatttaat     2400

catcctgcct ttcaaaagaa gacttgaatt cctatggaac aataaagaca cagcagaaaa     2460

cagggattct cctgtttcag aggaaataaa aatgacctgt caacaattta tccattatca     2520

ccgtgacctc tgtatccgaa acattgtcaa agaaagaagg tgtggtgcaa agacttctgc     2580

tggaactttc tgtggctgtg acctggtgag ctggctaatt gaagtcggcc ttgcctccga     2640

ccgtggtgaa gctgtgatat acggagacag gctggtacaa gggggagtca tccaacatat     2700

taccaacgag tatgaattcc gggatgagta cttgttttac agatttcttc aaaagagtcc     2760

tgaacagagt cctcctgcta ttaatgcaaa cactctccaa caggaaagat ataaagaaat     2820

tgagcattca tccccaccct cacattcccc taagacctaa attatgcagg ggagaaccct     2880

acatggaatc atattctagc cgcgtattca ttagttttta gctgggtgac cttgggcaag     2940

ttaacagagg caacctctct gagcctcagt tgtctcttct gtaaaatgtg aaaagatgtg     3000

ctcccaccac atgcgcaggg tctgtgattt tacatgtatg taaaacacat aggaagctga     3060

cttaggaaaa agagaaaacc aaattaaagt tctgataatg aatataatat agtcatcctt     3120

tagtatccaa ggggattggt tccaggactc ctgaagatcc caaaatctga ggatactcaa     3180

gtcccttata taaaatggtg taggccgggc atggtggctc acgcctgtaa tcccagtact     3240

ttgggaggcc gagtcaggtg gatcacctga ggtcaggagt tcaagaccag cctggccaac     3300

atggcgaaac cccgtctcta ctataaaata caaaaaatta gttgggtgtg gtggcgggtg     3360

cctgtaatcc cagctactca ggaggctgag gcaggagaat cgcttgaatc tgggaggcag     3420

aggttgctgt gagccgagat cgtgccactg cactccagcc tgagcaacag agcaagactc     3480

tatctcaaaa ataaaataaa ataaaataaa ataattaata aaatggtgta gtatttgcat     3540

ataacctatg cacattctcc catatagttt aatcatcttt agatacttat aatgcctaat     3600

acaatgtaaa tgctatgtaa atagttgttg ttatactgta ttgtttaggg aataacaata     3660

agaaaaacag tctgtacatg ttcactacag atgcaaccat tgttaagcct gactacatct     3720

ttttatctgc ggttgattga atctatggat gtggaacctg tgcatatgga gggtcaactg     3780

tactataaat aatacgaata tgccaacatt atataatcat tgctttctgc aactgtttac     3840

tataatttca aaattaatat cctattaact gttcctataa attatcaaat ttggcaagtg     3900

tattactagc aggagatgga ccttaaatta tgacaacttt atattttttg atagcatctc     3960

ttgaaaaaga attttaatga ttctaataag aggttctttt tcttttttcc atttccttga     4020

caaatagtac tcatttaaaa actagagggc taggcttagt ggctcacgcc tgtaatctca     4080

gcactttggg aggctgaggc gggcagatcg cttgaggtca ggagttcaag accagcccgg     4140

gcaacgtggt gaaacccggt ctgtactaaa aaaaaaaaaa aagaaaaaga aaaagaaaaa     4200

agaataccca ggtgtggtag tgcatgcctg tagtcccagc tactttggag actgaggtgg     4260

gagtacccct tgagcctggg aggcgcaggt tgcagtgaac caagatcaca tcactgcact     4320

tcaacctggg tgacagagca agaccctgtc tcaaaaacaa aaaacaagca aaaaaaacct     4380

agaggcacta ttttttttta aagtttgtct tttcttttct acccaaatta ctaatctatg     4440

ccattaagga aaggaataag aacctccata tgtattatta tctccacagt cctgcagaag     4500

tacaatctga tctttaactt tcatgctaca aataataatt tgagtagatt aatttgaatt     4560

ttatcaacaa aattattgcc atatgatgta tcatttctgt gtttgaacaa agcatcgtaa     4620

tgcaggataa cttctacttt attccctgta gttaaaaaaa aaaaaactat atagttcaag     4680

ccaatattta aaaattctaa acctaggctg ggcatggtga ctcatacctg taatcccagc     4740

actttgggag gccgaggcag gtgaattgct tcagcccagg agttcgagac cagcctggcc     4800

aatgtggtga aaccccatct ctactaaaaa aaaaaaaaaa aaaaaaaatt agccaggtgt     4860

ggtggtgtgc acctgtaatc ccagctaccc aggaggctga ggcaggaaaa ttgcttgaaa     4920

ccaggaggca gaggttgcag tgagctgaga tcgtgccact gcactccagc ctgagtgtca     4980

gagtgagact ctgtctcaga aaaaaaaaaa aaaattctaa agattacatt tagaatttag     5040

tctttttaaa gtgtccatgt ataaaaatat ataattttta aaattactaa atgttgcctt     5100

ttctcttagt ctaatatttt agctactaaa acaaaatata aactggatag cttataaaca     5160

acataaactt atttctcaca gttttggagg ctgtgaagtc caagattaag gcactaacag     5220

atctagtgtc tggtaaggca aatttctggc tcatagatgg taccttcttg ctgtgtcccc     5280

acatggtaga tgggaagaac tggtctcatt ggccccttat aaggacatta attccactca     5340

ataggctcca ccctcatgat ctaataacct ctcaaaggcc ctacctccta atactaacac     5400

attgaggatg tgacttcaac tttacatttc tacaggcaga gaagtggggc tgtgtaaatt     5460

cttcccatca gtacttgaat gttcatttaa caaataactt atcgagcatc tagcatgttc     5520

cagacacaat ctgaacactg agcacacaac agttggaaca aatatgattc ctatcctcat     5580

ggagcttcta ttctcctgtg aaaaacagat gttaaacatg attgaggatt aggtttcaac     5640

ataagaattc taggaggaca cagacattta gaccatagca tcttcaggta aactttatct     5700

tcagtaaatt aaagagatct atttagatga cctttgagca tcttaattat tagatgtcag     5760

tgctagttta acttatttta aacgtttcag atatttattt aattatactt taagtgtctc     5820

atgtaaaaaa gttatttata aaataattta tagggttaga gtcattgccc ttttaatgca     5880

acaaataaac agttttttaa aaacctgcat gggggccagg cgcggtggtt catacctgca     5940

atcccagcac tttgggaggt cgaggctggc ggatcacgag gtcaggagat cgagaccacc     6000

ctgattaatg cggtgaaatc ccgtctctac taaaaataca aaaaattagc cagacgtggt     6060

ggtgggcacc tatagtccca gctactcggg aggctgaggc aggagaatgg catgaacccg     6120

gaaggcggag cttgcagtga accaagatcg cgccactgca ctccagcctg ggcgacagag     6180

tgagactcca tcgcaaaaaa aaaaaaaaaa aaacctgcat ggaagcctag tatatttatt     6240

aataacaaat aaattatact ttagtgtact attaacctat accaatttta agttgtgatt     6300

agggaatggg gatgttttta agctgaattg tcttgctgcg gaactttcct tttttaataa     6360

gaccatatta tgactctgaa tgctcaaggg taagtctaag gcctcattgc tgttaccagg     6420

agatttttct agttacagta ataaagatgt taattcacat gcatgcagac aactgaaact     6480

caagtggaga atttgtttgt gaacaagtca tactacttct gttatttgca tgaatggaat     6540

ctgcaatatc tttttccatg ggagacccta aaagaaaacc ctggatcaga atgatctgca     6600

gtttcagata ataaaggctt ttaagagaca tttttagaat taaaaatatg ctaattttat     6660

taaatgaaaa tatttgtaac tgttaacttt ctcactgaca aagcaagttt ctcaataaaa     6720

tacctatttt aacttgcatt actgacatct tttctttgag taatctgaat aatgcagaag     6780

ccatcataga ggtcttttct atacattctc aatgttttct taaatgggtt tcctgagttc     6840

tgttcttcat gactctgggc tctgcaaaca gggtttccca attacgcatt ctataaacac     6900

ttttatgaat gagtcaatat gacattgagt ccttttcata catttcatca tttccaatat     6960

gtagagtgac agctagaaaa atgataaaat tttgattaaa acctatctct ttttcttcag     7020

catagtcaat tgttttctta actctcaatg agtaactcca tgcctagctt gtgcttagct     7080

ttcaatattt ttagactaag acaaagtgta tttggcattt tgagaacaac aattaatggt     7140

cagtaaattt ctaaagcaag aaaaatgtga aactagtgtt ttatatgttt gttacgcagc     7200

agaatgcggc tcttagtgtt tgccccttca tatctcatca tgtaaaatat taaattactt     7260

taggccactg cacataggta gtcctgtcat gagtgatggc tggagaaaag ttcaggatca     7320

taaatgttat catcattctt caagaaaaga tgagattata aatttctgca attggtatga     7380

taaaaggttg aaataattaa tgaaa                                           7405


<210>  2177
<211>  7405
<212>  DNA
<213>  homo sapiens

<400>  2177
ggggcctcgc ggccggcgag gggctgagct gacagggccg catcggctta ccccacctta       60

ctttatcgga acgtgcctaa gctgctgcag ctggcacccg gttgcgctcg gcgaagaggg      120

ctgggggcgg gagatgacgg tggtcttctc cctgcttggc accctgcgag caccagctcc      180

cttctcctcg ccactccaag gttgcagacg aagcagagat ctggttggag ttggagggtg      240

agagaaaatg aattctaatt tacctgcaga gaacttaacc attgcagtca atatgaccaa      300

gactttgcct acagcagtaa cgcatggatt taattccact aatgacccac cttcaatgtc      360

aattacaagg ctttttccag ccttactgga atgctttggc attgtccttt gtggctacat      420

agcaggaagg gccaatgtca taacatcaac ccaggccaaa ggactaggaa attttgtctc      480

cagatttgca cttccagctt tattattcaa aaacatggtt gtacttaatt tttccaatgt      540

ggactggtcc ttcctatata gtatcttaat tgccaaagct tctgtatttt tcattgtatg      600

tgtattaacc ttattggttg ccagtcctga tagtcgattt agcaaagctg gactattccc      660

tatttttgct acacaaagta atgactttgc attgggatac cctatagttg aagctttata      720

tcaaactaca tacccagaat atctccagta catttatttg gtggcaccaa tatctcttat      780

gatgttaaac cctatagggt ttattttctg tgaaatccaa aagtggaaag acactcaaaa      840

tgcttctcaa aataaaataa aaattgtggg actcggactc ctgcgtgtat tacagaaccc      900

aatagtattt atggtcttca ttggcatcgc cttcaatttt attcttgatc gaaaggtacc      960

tgtatatgtc gaaaattttc ttgatggact tggaaattct ttttctggat cagccctatt     1020

ttatcttggt ctcacgatgg tgggaaaaat aaagagactg aagaagtcgg catttgtagt     1080

actaattctt ctcatcacag ctaaacttct ggtgctgcca cttctgtgca gagaaatggt     1140

ggaactcttg gacaagggcg acagtgtggt gaaccataca agtttatcaa attatgcatt     1200

tctgtatggt gtatttcctg tagcaccagg agtggctatc tttgcaacac aattcaacat     1260

ggaagtagaa attataacct cagggatggt gataagcaca tttgtgtctg ctcccatcat     1320

gtacgtttct gcctggttac tgacctttcc cactatggac cctaagccat tggcatatgc     1380

catccagaat gttagttttg atataagtat tgtcagcctg atctccttga tctggtctct     1440

ggctattctt cttttgagta agaaatataa acagcttcct catatgctta caactaattt     1500

actcattgct cagtctattg tctgtgctgg aatgatgata tggaattttg ttaaagaaaa     1560

aaattttgtt ggacaaattt tggtgtttgt tctattgtac agctccctct atagcaccta     1620

cctgtggaca ggccttctag caatttcttt gtttcttttg aaaaagcgag agagggtaca     1680

aattcctgtt ggaataatca taatatctgg ctggggaatt cctgctctcc ttgttggtgt     1740

tcttttgata actggaaaac acaatggaga tagcattgac tcagccttct tttatggaaa     1800

agaacagatg atcaccacag cagtcaccct gttctgcagc atcctgatag ctggcatatc     1860

cctcatgtgc atgaaccaga ctgcccaagc aggaagctat gaaggtttcg atcagtctca     1920

gagccacaaa gtggtggagc ctggaaatac tgcttttgag gagagtccag caccagtaaa     1980

tgaaccagaa ctttttacaa gctctattcc agaaacaagt tgctgctcct gctccatggg     2040

aaatggtgaa ttacactgcc catcaataga gccaatagca aacacaagca ccagtgagcc     2100

tgtgattcct tcgtttgaga aaaacaatca ttgtgtgagt cgctgtaact cccagagctg     2160

catattagcc caggaagaag aacagtatct acagagtgga gaccagcaac tgacccgaca     2220

tgtgttgctg tgtttacttc tcatcattgg cctgttcgct aatctttcca gttgtttatg     2280

gtggctattc aaccaagagc ctggaagact ttatgttgag ttacagtttt tctgtgccgt     2340

gtttaacttt ggtcagggat ttatttcctt tggaatcttt ggattagata aacatttaat     2400

catcctgcct ttcaaaagaa gacttgaatt cctatggaac aataaagaca cagcagaaaa     2460

cagggattct cctgtttcag aggaaataaa aatgacctgt caacaattta tccattatca     2520

ccgtgacctc tgtatccgaa acattgtcaa agaaagaagg tgtggtgcaa agacttctgc     2580

tggaactttc tgtggctgtg acctggtgag ctggctaatt gaagtcggcc ttgcctccga     2640

ccgtggtgaa gctgtgatat acggagacag gctggtacaa gggggagtca tccaacatat     2700

taccaacgag tatgaattcc gggatgagta cttgttttac agatttcttc aaaagagtcc     2760

tgaacagagt cctcctgcta ttaatgcaaa cactctccaa caggaaagat ataaagaaat     2820

tgagcattca tccccaccct cacattcccc taagacctaa attatgcagg ggagaaccct     2880

acatggaatc atattctagc cgcgtattca ttagttttta gctgggtgac cttgggcaag     2940

ttaacagagg caacctctct gagcctcagt tgtctcttct gtaaaatgtg aaaagatgtg     3000

ctcccaccac atgcgcaggg tctgtgattt tacatgtatg taaaacacat aggaagctga     3060

cttaggaaaa agagaaaacc aaattaaagt tctgataatg aatataatat agtcatcctt     3120

tagtatccaa ggggattggt tccaggactc ctgaagatcc caaaatctga ggatactcaa     3180

gtcccttata taaaatggtg taggccgggc atggtggctc acgcctgtaa tcccagtact     3240

ttgggaggcc gagtcaggtg gatcacctga ggtcaggagt tcaagaccag cctggccaac     3300

atggcgaaac cccgtctcta ctataaaata caaaaaatta gttgggtgtg gtggcgggtg     3360

cctgtaatcc cagctactca ggaggctgag gcaggagaat cgcttgaatc tgggaggcag     3420

aggttgctgt gagccgagat cgtgccactg cactccagcc tgagcaacag agcaagactc     3480

tatctcaaaa ataaaataaa ataaaataaa ataattaata aaatggtgta gtatttgcat     3540

ataacctatg cacattctcc catatagttt aatcatcttt agatacttat aatgcctaat     3600

acaatgtaaa tgctatgtaa atagttgttg ttatactgta ttgtttaggg aataacaata     3660

agaaaaacag tctgtacatg ttcactacag atgcaaccat tgttaagcct gactacatct     3720

ttttatctgc ggttgattga atctatggat gtggaacctg tgcatatgga gggtcaactg     3780

tactataaat aatacgaata tgccaacatt atataatcat tgctttctgc aactgtttac     3840

tataatttca aaattaatat cctattaact gttcctataa attatcaaat ttggcaagtg     3900

tattactagc aggagatgga ccttaaatta tgacaacttt atattttttg atagcatctc     3960

ttgaaaaaga attttaatga ttctaataag aggttctttt tcttttttcc atttccttga     4020

caaatagtac tcatttaaaa actagagggc taggcttagt ggctcacgcc tgtaatctca     4080

gcactttggg aggctgaggc gggcagatcg cttgaggtca ggagttcaag accagcccgg     4140

gcaacgtggt gaaacccggt ctgtactaaa aaaaaaaaaa aagaaaaaga aaaagaaaaa     4200

agaataccca ggtgtggtag tgcatgcctg tagtcccagc tactttggag actgaggtgg     4260

gagtacccct tgagcctggg aggcgcaggt tgcagtgaac caagatcaca tcactgcact     4320

tcaacctggg tgacagagca agaccctgtc tcaaaaacaa aaaacaagca aaaaaaacct     4380

agaggcacta ttttttttta aagtttgtct tttcttttct acccaaatta ctaatctatg     4440

ccattaagga aaggaataag aacctccata tgtattatta tctccacagt cctgcagaag     4500

tacaatctga tctttaactt tcatgctaca aataataatt tgagtagatt aatttgaatt     4560

ttatcaacaa aattattgcc atatgatgta tcatttctgt gtttgaacaa agcatcgtaa     4620

tgcaggataa cttctacttt attccctgta gttaaaaaaa aaaaaactat atagttcaag     4680

ccaatattta aaaattctaa acctaggctg ggcatggtga ctcatacctg taatcccagc     4740

actttgggag gccgaggcag gtgaattgct tcagcccagg agttcgagac cagcctggcc     4800

aatgtggtga aaccccatct ctactaaaaa aaaaaaaaaa aaaaaaaatt agccaggtgt     4860

ggtggtgtgc acctgtaatc ccagctaccc aggaggctga ggcaggaaaa ttgcttgaaa     4920

ccaggaggca gaggttgcag tgagctgaga tcgtgccact gcactccagc ctgagtgtca     4980

gagtgagact ctgtctcaga aaaaaaaaaa aaaattctaa agattacatt tagaatttag     5040

tctttttaaa gtgtccatgt ataaaaatat ataattttta aaattactaa atgttgcctt     5100

ttctcttagt ctaatatttt agctactaaa acaaaatata aactggatag cttataaaca     5160

acataaactt atttctcaca gttttggagg ctgtgaagtc caagattaag gcactaacag     5220

atctagtgtc tggtaaggca aatttctggc tcatagatgg taccttcttg ctgtgtcccc     5280

acatggtaga tgggaagaac tggtctcatt ggccccttat aaggacatta attccactca     5340

ataggctcca ccctcatgat ctaataacct ctcaaaggcc ctacctccta atactaacac     5400

attgaggatg tgacttcaac tttacatttc tacaggcaga gaagtggggc tgtgtaaatt     5460

cttcccatca gtacttgaat gttcatttaa caaataactt atcgagcatc tagcatgttc     5520

cagacacaat ctgaacactg agcacacaac agttggaaca aatatgattc ctatcctcat     5580

ggagcttcta ttctcctgtg aaaaacagat gttaaacatg attgaggatt aggtttcaac     5640

ataagaattc taggaggaca cagacattta gaccatagca tcttcaggta aactttatct     5700

tcagtaaatt aaagagatct atttagatga cctttgagca tcttaattat tagatgtcag     5760

tgctagttta acttatttta aacgtttcag atatttattt aattatactt taagtgtctc     5820

atgtaaaaaa gttatttata aaataattta tagggttaga gtcattgccc ttttaatgca     5880

acaaataaac agttttttaa aaacctgcat gggggccagg cgcggtggtt catacctgca     5940

atcccagcac tttgggaggt cgaggctggc ggatcacgag gtcaggagat cgagaccacc     6000

ctgattaatg cggtgaaatc ccgtctctac taaaaataca aaaaattagc cagacgtggt     6060

ggtgggcacc tatagtccca gctactcggg aggctgaggc aggagaatgg catgaacccg     6120

gaaggcggag cttgcagtga accaagatcg cgccactgca ctccagcctg ggcgacagag     6180

tgagactcca tcgcaaaaaa aaaaaaaaaa aaacctgcat ggaagcctag tatatttatt     6240

aataacaaat aaattatact ttagtgtact attaacctat accaatttta agttgtgatt     6300

agggaatggg gatgttttta agctgaattg tcttgctgcg gaactttcct tttttaataa     6360

gaccatatta tgactctgaa tgctcaaggg taagtctaag gcctcattgc tgttaccagg     6420

agatttttct agttacagta ataaagatgt taattcacat gcatgcagac aactgaaact     6480

caagtggaga atttgtttgt gaacaagtca tactacttct gttatttgca tgaatggaat     6540

ctgcaatatc tttttccatg ggagacccta aaagaaaacc ctggatcaga atgatctgca     6600

gtttcagata ataaaggctt ttaagagaca tttttagaat taaaaatatg ctaattttat     6660

taaatgaaaa tatttgtaac tgttaacttt ctcactgaca aagcaagttt ctcaataaaa     6720

tacctatttt aacttgcatt actgacatct tttctttgag taatctgaat aatgcagaag     6780

ccatcataga ggtcttttct atacattctc aatgttttct taaatgggtt tcctgagttc     6840

tgttcttcat gactctgggc tctgcaaaca gggtttccca attacgcatt ctataaacac     6900

ttttatgaat gagtcaatat gacattgagt ccttttcata catttcatca tttccaatat     6960

gtagagtgac agctagaaaa atgataaaat tttgattaaa acctatctct ttttcttcag     7020

catagtcaat tgttttctta actctcaatg agtaactcca tgcctagctt gtgcttagct     7080

ttcaatattt ttagactaag acaaagtgta tttggcattt tgagaacaac aattaatggt     7140

cagtaaattt ctaaagcaag aaaaatgtga aactagtgtt ttatatgttt gttacgcagc     7200

agaatgcggc tcttagtgtt tgccccttca tatctcatca tgtaaaatat taaattactt     7260

taggccactg cacataggta gtcctgtcat gagtgatggc tggagaaaag ttcaggatca     7320

taaatgttat catcattctt caagaaaaga tgagattata aatttctgca attggtatga     7380

taaaaggttg aaataattaa tgaaa                                           7405


<210>  2178
<211>  2941
<212>  DNA
<213>  homo sapiens

<400>  2178
cggccgctgc agcagcgcgg gccgggccag ggggcgcctc gcgcggcagc gactctggca       60

ggcgctgcag tgaagctgga cccgcaggcg ggcgtgcgtg gagcgggggc cgcggccgcg      120

ccgcagagat gtgactcggg ccgaaggcca gctggagcgt cggcgctgcg gggccgcggg      180

ggtcgaatgt tcgtggcatc agagagaaag atgagagctc accaggtgct caccttcctc      240

ctgctcttcg tgatcacctc ggtggcctct gaaaacgcca gcacatcccg aggctgtggg      300

ctggacctcc tccctcagta cgtgtccctg tgcgacctgg acgccatctg gggcattgtg      360

gtggaggcgg tggccggggc gggcgccctg atcacactgc tcctgatgct catcctcctg      420

gtgcggctgc ccttcatcaa ggagaaggag aagaagagcc ctgtgggcct ccactttctg      480

ttcctcctgg ggaccctggg cctctttggg ctgacgtttg ccttcatcat ccaggaggac      540

gagaccatct gctctgtccg ccgcttcctc tggggcgtcc tctttgcgct ctgcttctcc      600

tgcctgctga gccaggcatg gcgcgtgcgg aggctggtgc ggcatggcac gggccccgcg      660

ggctggcagc tggtgggcct ggcgctgtgc ctgatgctgg tgcaagtcat catcgctgtg      720

gagtggctgg tgctcaccgt gctgcgtgac acaaggccag cctgcgccta cgagcccatg      780

gactttgtga tggccctcat ctacgacatg gtactgcttg tggtcaccct ggggctggcc      840

ctcttcactc tgtgcggcaa gttcaagagg tggaagctga acggggcctt cctcctcatc      900

acagccttcc tctctgtgct catctgggtg gcctggatga ccatgtacct cttcggcaat      960

gtcaagctgc agcaggggga tgcctggaac gaccccacct tggccatcac gctggcggcc     1020

agcggctggg tcttcgtcat cttccacgcc atccctgaga tccactgcac ccttctgcca     1080

gccctgcagg agaacacgcc caactacttc gacacgtcgc agcccaggat gcgggagacg     1140

gccttcgagg aggacgtgca gctgccgcgg gcctatatgg agaacaaggc cttctccatg     1200

gatgaacaca atgcagctct ccgaacagca ggatttccca acggcagctt gggaaaaaga     1260

cccagtggca gcttggggaa aagacccagc gctccgttta gaagcaacgt gtatcagcca     1320

actgagatgg ccgtcgtgct caacggtggg accatcccaa ctgctccgcc aagtcacaca     1380

ggaagacacc tttggtgaaa gactttaagt tccagagaat cagaatttct cttaccgatt     1440

tgcctccctg gctgtgtctt tcttgaggga gaaatcggta acagttgccg aaccaggccg     1500

cctcacagcc aggaaatttg gaaatcctag ccaaggggat ttcgtgtaaa tgtgaacact     1560

gacgaactga aaagctaaca ccgactgccc gcccctcccc tgccacacac acagacacgt     1620

aataccagac caacctcaat ccccgcaaac taaagcaaag ctaattgcaa atagtattag     1680

gctcactgga aaatgtggct gggaagactg tttcatcctc tgggggtaga acagaaccaa     1740

attcacagct ggtgggccag actggtgttg gttggaggtg gggggctccc actcttatca     1800

cctctcccca gcaagtgctg gaccccaggt agcctcttgg agatgaccgt tgcgttgagg     1860

acaaatgggg actttgccac cggcttgcct ggtggtttgc acatttcagg ggggtcagga     1920

gagttaagga ggttgtgggt gggattccaa ggtgaggccc aactgaatcg tggggtgagc     1980

tttatagcca gtagaggtgg agggaccctg gcatgtgcca aagaagaggc cctctgggtg     2040

atgaagtgac catcacattt ggaaagtgat caaccactgt tccttctatg gggctcttgc     2100

tctagtgtct atggtgagaa cacaggcccc gccccttccc ttgtagagcc atagaaatat     2160

tctggcttgg ggcagcagtc ccttcttccc ttgatcatct cgccctgttc ctacacttac     2220

gggtgtatct ccaaatcctc tcccaatttt attcccttat tcatttcaag agctccaatg     2280

gggtctccag ctgaaagccc ctccgggagg caggttggaa ggcaggcacc acggcaggtt     2340

ttccgcgatg atgtcaccta gcagggcttc aggggttccc actaggatgc agagatgacc     2400

tctcgctgcc tcacaagcag tgacacctcg ggtcctttcc gttgctatgg tgaaaattcc     2460

tggatggaat ggatcacatg agggtttctt gttgcttttg gagggtgtgg gggatatttt     2520

gttttggttt ttctgcaggt tccatgaaaa cagccctttt ccaagcccat tgtttctgtc     2580

atggtttcca tctgtcctga gcaagtcatt cctttgttat ttagcatttc gaacatctcg     2640

gccattcaaa gcccccatgt tctctgcact gtttggccag cataacctct agcatcgatt     2700

caaagcagag ttttaacctg acggcatgga atgtataaat gagggtgggt ccttctgcag     2760

atactctaat cactacattg ctttttctat aaaactaccc ataagccttt aacctttaaa     2820

gaaaaatgaa aaaggttagt gtttgggggc cgggggagga ctgaccgctt cataagccag     2880

tacgtctgag ctgagtatgt ttcaataaac cttttgatat ttctcaaaaa aaaaaaaaaa     2940

a                                                                     2941


<210>  2179
<211>  2052
<212>  DNA
<213>  homo sapiens

<400>  2179
gggtctgcgg gaagcccgag ccggggcggg cccgagtcaa aggcaagtga aggtggaagc       60

ggccgcggcg gcagcaggcc accatggcgg agctgcagga ggtgcagatc acagaggaga      120

agccactgtt gccaggacag acgcctgagg cggccaagga ggctgagtta gctgcccgaa      180

tcctcctgga ccagggacag actcactctg tggagacacc atacggctct gtcactttca      240

ctgtctatgg cacccccaaa cccaaacgcc cagcgatcct tacctaccac gatgtgggac      300

tcaactataa atcttgcttc cagccactgt ttcagttcga ggacatgcag gaaatcattc      360

agaactttgt gcgggttcat gtggatgccc ctggaatgga agagggagcc cctgtgttcc      420

ctttgggata tcagtaccca tctctggacc agcttgcaga catgatccct tgcgtcctgc      480

agtacctaaa tttctctaca ataattggag ttggtgttgg agctggagcc tacatcctgg      540

cgagatatgc tcttaaccac ccggacactg ttgaaggtct tgtcctcatc aacattgatc      600

ccaatgccaa gggttggatg gattgggcag cccacaagct aacaggcctc acctcttcca      660

ttccggagat gatccttgga catcttttca gccaggaaga gctctctgga aattctgagt      720

tgatacaaaa gtacagaaat atcattacac atgcacccaa cctggataac attgaattgt      780

actggaacag ctacaacaac cgccgagacc tgaactttga gcgtggaggt gatatcaccc      840

tcaggtgtcc tgtgatgctg gtggtaggag accaagcacc tcatgaagat gcagtggtgg      900

aatgtaactc aaaactggac cccacccaga cctcgttcct caagatggct gactccggag      960

gtcagcccca gctgactcag ccaggcaagc tgaccgaggc cttcaagtac ttcctgcaag     1020

gcatgggcta catggcctca tcctgcatga ctcgcctgtc ccggtctcgt acagcctctc     1080

tgaccagtgc agcatccgtt gatggcaacc ggtcccgctc tcgcaccctg tcccagagca     1140

gcgagtctgg aactctttct tcggggcccc cggggcacac catggaggtc tcctgttgaa     1200

tggcccttgt tgccctagag tgggacccag ccctcacctc ccccagagct aacctgggag     1260

gtgctgaagg ggcattgggc caccgtaagc aagggaaaaa gggcagatca tgcggggaga     1320

tgaccttgat ctttgattgc taccctaacc ttgaccttta acccgtgatt ccccccagct     1380

cctggaagag atgtcctaat atctcttagg gacccagacc cctaaattct cctcctcccc     1440

cattttgatg ttaaggtgga gagggcatat gcatcctctg tcctgatcta ggtgtctata     1500

gctgaggggt aagaggttgt tgtagttgtc ctggtgcctc catcagactc tccctacttg     1560

tcccatattt gcaaggggag gggatttggg gctggggctc cattcaccaa agctgaggtg     1620

gcttctcatt aaccctttag gactctgaag ggtatggacc tacgtgaatg tgtgtcaggg     1680

ggagacttgc tggtgggtta gtggtcctca ggatgtgata gaaacatcca gtgtaaaaag     1740

gaagttggaa tgggagttgg cgggcagtga acgagtgtgg ggaaggattg gtgctggggc     1800

aacaggaagg ggcctggggc cgtttggctg cactaacttt ggtagctcag tgtgcatcta     1860

gagtgggact ggggagggag ctaagcttgg gctgggctgc ttggggcttg gcatagggtg     1920

gaaagggcta ccctggggct ctgaccacac tgtagtatgt gtggagggtg ccctcccgtc     1980

tcccacaact tctgctataa caataaactg tagaggaatc tgagtaccgt taaaaaaaaa     2040

aaaaaaaaaa aa                                                         2052


<210>  2180
<211>  2119
<212>  DNA
<213>  homo sapiens

<400>  2180
gggtctgcgg gaagcccgag ccggggcggg cccgagtcaa aggcaagtga aggtggaagc       60

ggccgcggcg gcagcagacc ccagagtcag aaggagtgag aaccctgacc cctaatccca      120

ctgcatccag ccaataggag cccagccacc atggcggagc tgcaggaggt gcagatcaca      180

gaggagaagc cactgttgcc aggacagacg cctgaggcgg ccaaggaggc tgagttagct      240

gcccgaatcc tcctggacca gggacagact cactctgtgg agacaccata cggctctgtc      300

actttcactg tctatggcac ccccaaaccc aaacgcccag cgatccttac ctaccacgat      360

gtgggactca actataaatc ttgcttccag ccactgtttc agttcgagga catgcaggaa      420

atcattcaga actttgtgcg ggttcatgtg gatgcccctg gaatggaaga gggagcccct      480

gtgttccctt tgggatatca gtacccatct ctggaccagc ttgcagacat gatcccttgc      540

gtcctgcagt acctaaattt ctctacaata attggagttg gtgttggagc tggagcctac      600

atcctggcga gatatgctct taaccacccg gacactgttg aaggtcttgt cctcatcaac      660

attgatccca atgccaaggg ttggatggat tgggcagccc acaagctaac aggcctcacc      720

tcttccattc cggagatgat ccttggacat cttttcagcc aggaagagct ctctggaaat      780

tctgagttga tacaaaagta cagaaatatc attacacatg cacccaacct ggataacatt      840

gaattgtact ggaacagcta caacaaccgc cgagacctga actttgagcg tggaggtgat      900

atcaccctca ggtgtcctgt gatgctggtg gtaggagacc aagcacctca tgaagatgca      960

gtggtggaat gtaactcaaa actggacccc acccagacct cgttcctcaa gatggctgac     1020

tccggaggtc agccccagct gactcagcca ggcaagctga ccgaggcctt caagtacttc     1080

ctgcaaggca tgggctacat ggcctcatcc tgcatgactc gcctgtcccg gtctcgtaca     1140

gcctctctga ccagtgcagc atccgttgat ggcaaccggt cccgctctcg caccctgtcc     1200

cagagcagcg agtctggaac tctttcttcg gggcccccgg ggcacaccat ggaggtctcc     1260

tgttgaatgg cccttgttgc cctagagtgg gacccagccc tcacctcccc cagagctaac     1320

ctgggaggtg ctgaaggggc attgggccac cgtaagcaag ggaaaaaggg cagatcatgc     1380

ggggagatga ccttgatctt tgattgctac cctaaccttg acctttaacc cgtgattccc     1440

cccagctcct ggaagagatg tcctaatatc tcttagggac ccagacccct aaattctcct     1500

cctcccccat tttgatgtta aggtggagag ggcatatgca tcctctgtcc tgatctaggt     1560

gtctatagct gaggggtaag aggttgttgt agttgtcctg gtgcctccat cagactctcc     1620

ctacttgtcc catatttgca aggggagggg atttggggct ggggctccat tcaccaaagc     1680

tgaggtggct tctcattaac cctttaggac tctgaagggt atggacctac gtgaatgtgt     1740

gtcaggggga gacttgctgg tgggttagtg gtcctcagga tgtgatagaa acatccagtg     1800

taaaaaggaa gttggaatgg gagttggcgg gcagtgaacg agtgtgggga aggattggtg     1860

ctggggcaac aggaaggggc ctggggccgt ttggctgcac taactttggt agctcagtgt     1920

gcatctagag tgggactggg gagggagcta agcttgggct gggctgcttg gggcttggca     1980

tagggtggaa agggctaccc tggggctctg accacactgt agtatgtgtg gagggtgccc     2040

tcccgtctcc cacaacttct gctataacaa taaactgtag aggaatctga gtaccgttaa     2100

aaaaaaaaaa aaaaaaaaa                                                  2119


<210>  2181
<211>  4257
<212>  DNA
<213>  homo sapiens

<400>  2181
agtgtgtgga gaagccactc tcccgaaacc agagggatgg ggccggctgt gcagtagaac       60

ggggatcgaa aagaggaaaa caagggcacg aagaccagcg agaaagaaga ggacacctgg      120

gaaaggcgga agcagaagac ggggaaggga aaagaaaccc aaagcaggtg gaaaccagat      180

ctagagcaac accgtcaggt tcacagtttg tttttctaga agagaagaaa gtacctgagg      240

attgctcttt tttcctaccg ttaatgaaaa ctacttttgt cttcatcata aaagaaaaaa      300

ctaaggggag gtaaaggcag tctcctgttt tattaggggg agaggtgaag ggaaatccag      360

gctcactttc tgaataagcc actgcctggt gcacagagca gaaccatcct ggtttctgaa      420

gacacatccc tttcagcaga attccagccg gagtcgctgg cacagttcta tttttatatt      480

taaatgtatg tctcccctgg cctttttttt tttttttttt tttagcaaca cttttcttgt      540

ttgtaaacgc gagtgaccag aaagtgtgaa tgcggagtag gaatattttt cgtgttctct      600

tttatctgct tgcctttttt agagagtagc agtggttcct atttcggaaa aggacgttct      660

aattcaaagc tctctcccaa tatatttaca cgaatacgca tttagaaagg gaggcagctt      720

ttgaggttgc aatcctactg agaaggatgg aagaaggagc caggcaccga aacaacaccg      780

aaaagaaaca cccaggtggg ggcgagtcgg acgccagccc cgaggctggt tccggagggg      840

gcggagtagc cctgaagaaa gagatcggat tggtcagtgc ctgtggtatc atcgtaggga      900

acatcatcgg ctctggaatc tttgtctcgc caaagggagt gctggagaat gctggttctg      960

tgggccttgc tctcatcgtc tggattgtga cgggcttcat cacagttgtg ggagccctct     1020

gctatgctga actcggggtc accatcccca aatctggagg tgactactcc tatgtcaagg     1080

acatcttcgg aggactggct gggttcctga ggctgtggat tgctgtgctg gtgatctacc     1140

ccaccaacca ggctgtcatc gccctcacct tctccaacta cgtgctgcag ccgctcttcc     1200

ccacctgctt ccccccagag tctggccttc ggctcctggc tgccatctgc ttattgctcc     1260

tcacatgggt caactgttcc agtgtgcggt gggccacccg ggttcaagac atcttcacag     1320

ctgggaagct cctggccttg gccctgatta tcatcatggg gattgtacag atatgcaaag     1380

gagagtactt ctggctggag ccaaagaatg catttgagaa tttccaggaa cctgacatcg     1440

gcctcgtcgc actggctttc cttcagggct cctttgccta tggaggctgg aactttctga     1500

attacgtgac tgaggagctt gttgatccct acaagaacct tcccagagcc atcttcatct     1560

ccatcccact ggtcacattt gtgtatgtct ttgccaatgt cgcttatgtc actgcaatgt     1620

ccccccagga gctgctggca tccaacgccg tcgctgtgac ttttggagag aagctcctag     1680

gagtcatggc ctggatcatg cccatttctg ttgccctgtc cacatttgga ggagttaatg     1740

ggtctctctt cacctcctct cggctgttct tcgctggagc ccgagagggc caccttccca     1800

gtgtgttggc catgatccac gtgaagcgct gcaccccaat cccagccctg ctcttcacat     1860

gcatctccac cctgctgatg ctggtcacca gcgacatgta cacactcatc aactatgtgg     1920

gcttcatcaa ctacctcttc tatggggtca cggttgctgg acagatagtc cttcgctgga     1980

agaagcctga tatcccccgc cccatcaaga tcaacctgct gttccccatc atctacttgc     2040

tgttctgggc cttcctgctg gtcttcagcc tgtggtcaga gccggtggtg tgtggcattg     2100

gcctggccat catgctgaca ggagtgcctg tctatttcct gggtgtttac tggcaacaca     2160

agcccaagtg tttcagtgac ttcattgagc tgctaaccct ggtgagccag aagatgtgtg     2220

tggtcgtgta ccccgaggtg gagcggggct cagggacaga ggaggctaat gaggacatgg     2280

aggagcagca gcagcccatg taccaaccca ctcccacgaa ggacaaggac gtggcggggc     2340

agccccagcc ctgaggacca ccattccctg gctactctct ccttcctccc ccttttatcc     2400

tacctccctg ccttggtcct gccaacacat gcgagtacac acacacccct ctctctgctt     2460

ttgtcaggca gtggtaggac tttggtgtgg gtggtgagaa attgtaaaca aaaactgaca     2520

ttcataccca aagaaccagc ctctcacccc agggtccatg tcccaggccc cactccagtg     2580

ctgcccacac tcccagctgc tggaggagag gggagatgcc aaggtgccct gcaggacctc     2640

cctccgggcc acaccctcag ctgcctcttc aggaaccgga gctcattact gccttccctc     2700

ccagggaggc cccttcagag aggagaggcc acaggagctg cattgtgggg ggacaggctc     2760

aagcaattct gtccccatca aggggtcagc tggagagacc caagacccta tctgttcacc     2820

agggacccaa aatccaaggg gatgcttccc tctgccctct ttcctgcccc tccccatcat     2880

acctgcaccc accccagcca gggctccctg tccagaattc ggttctcctc aggacgccaa     2940

ctcccagagc taaggaccaa ggagaagaac agcctctcca cccccaagcc aggcggttga     3000

ggaacatatt gagaaaggtt cagattgcag aaacccagcc ctgcccctgc ctcctgcatc     3060

cagcccccaa catggtgcca aagcttccag aagccaaaaa gcttctgatt tttaaggtag     3120

tgggcatctc tctcctaatg acgaagctgc tcagcaactc cacctgcccg ccgcaggaag     3180

gagcagtccc ctgctatccc tgcagccact cccagcacac ccgcacacag ccagcaccac     3240

cgcccccacc gtgcacttct cctctctggg ccttggcttg ggaccaggta cgaaggatcc     3300

ccaagccctt caggcctgag atcagagcca gatcagcctt aagtcacctc ccatccaaga     3360

acttggccta aaaatactcc cctatttcta accctcagga cggatctgat attaaatgcc     3420

ttccctggga ggaagggtgc tttccccctc cctagaggtg cccattccat accctgggag     3480

actgaggaga gcattggctg aagcccagtt cctttcccat ccatccccaa ctccaataat     3540

cccccactcc tcgcaggtct cagtgtcatg ctgtcttggg gcagggtgaa agggtagtgg     3600

cagcagggcg cccactctgg agatcctcaa aaaaggccct cctctgtggc tggcagcctc     3660

tgacctttcc ctgggcttca aaggaaggct atggagtttg ctgtgggccc tgcaaccttc     3720

ccagccactc ctgctgcact aaggacttag gatcctttta tcacaaatcg ggattctctc     3780

ccccaccccg aattctgtct gcttaaactg gaatacacag gagcccttcc tggcctggat     3840

ggtgtctccc agcttccccg cccagcttgc ccaccccata gttggtgaga tgccaagttt     3900

ggtctgagtt gtgacccctt cagagtagat gcccggcagg ctggggttgg cccctggagg     3960

gtcaggggac catcttctta ttccctcttt tctcattcct ccaacttcct cccctccttc     4020

aattattttt ttgtaaagtt gatgccttac tttttggata aatatttttg aagctggtat     4080

ttctatttct tttggatttt ttttaatgta aggttgtttt gggggatgga gttagaacct     4140

taatgataat ttctttcgtt tggtgtaggt tttagagatt tgttttgtgg agaggttttt     4200

ttcttttgat gtaataaaat ttaaaatgga aatgaaaaaa aaaaaaaaaa aaaaaaa        4257


<210>  2182
<211>  2086
<212>  DNA
<213>  homo sapiens

<400>  2182
cggaccctcc cgcggccgac tggaggcccg gagcaggggc ggagtttccg gcggcagcgc       60

cactcgggcg tcgggtgacg ctaggcggac ggaccatcat gtgacacgga agtagctccg      120

aacaggaaga ggacgaaaaa aataaccgtc cgcgacgccg agacaaaccg gacccgcaac      180

caccatgaac agcaaaggtc aatatccaac acagccaacc taccctgtgc agcctcctgg      240

gaatccagta taccctcaga ccttgcatct tcctcaggct ccaccctata ccgatgctcc      300

acctgcctac tcagagtctg tggctgttgg gcctttaggt tccacaatcc ccatggctta      360

ttatccagtc ggtcccatct atccacctgg ctccacagtg ctggtggaag gagggtatga      420

tgcaggtgcc agatttggag ctggggctac tgctggcaac attcctcctc cacctcctgg      480

atgccctccc aatgctgctc agcttgcagt catgcaggga gccaacgtcc tcgtaactca      540

gcggaagggg aacttcttca tgggtggttc agatggtggc tacaccatct ggtgaggaac      600

caaggccacc tctgtgccgg gaaagacatc acataccttc agcacttctc acaatgtaac      660

tgctttagtc atattaacct gaagttgcag tttagacaca tgttgttggg gtgtctttct      720

ggtgcccaaa ctttcaggca cttttcaaat ttaataagga accatgtaat ggtagcagta      780

cctccctaaa gcattttgag gtaggggagg tatccattca taaaatgaat gtgggtgaag      840

ccgccctaag gattttcctt taatttctct ggagtaatac tgtaccatac tggtctttgc      900

ttttagtaat aaaacatcaa attaggtttg gagggaactt tgatcttcct aagaattaaa      960

gttgccaaat tattctgatt ggtctttaat ctcctttaag tctttgatat atattacttg     1020

ttataaatgg aacgcattag ttgtctgcct tttcctttcc atcccttgcc ccacccatcc     1080

catctccaac cctagtcttc catttcctcc cgccagtctc cattgaatca atggtgcagg     1140

acagaaagcc agtcagacta atttccttct ttcctcgcac ttctccccac tcgtcatctt     1200

ttaactagtg tttcacaagg atcctctgaa accctctctg tgccccaagt acagatgcca     1260

ttacttctgc tttcgtatct cctcaggcaa aagtggaggg tgccttatgg gccctcctca     1320

taggttgtct ctgcatacac gaacctaacc caaatttgct ttggtgccag aaaaactgag     1380

ctatgtttga acaaagatgt cgtgcaaact gtactgtgaa caacagttgg tttaaaatat     1440

gaggggcaag gaggaggatg catttcaaaa gcttgattga tgtgttcaga gctaaattaa     1500

gaggagtttt cagatcaaaa actggttacc attttttgtc agagtgtctg atgcggccac     1560

tcattcggct ccccagaatt cctagactgg gttaataggg tcatattgtg aatgtctcac     1620

tacaaaatga cttgagtcca gtgaaatctc attagggttt aagaatattt cagggatcct     1680

taatgttttg atttttgttt tctgaaattg gattttattt tattttatct tataatttca     1740

gttcatctaa attgtgtgtt ctgtacatgt gatgtttgac tgtaccattg actgttatgg     1800

aagttcagcg ttgtatgtct ctctctacac tgtggtgcac ttaacttgtg gaatttttat     1860

actaaaaatg tagaataaag actattttga agatttgaat aaagtgatga agttgcatta     1920

cacctcactg caaggattct ttacttagct tgtttttaga tttcttctat atatatttta     1980

tttatatccc atctagaatt cagctaggtg ctgctgctgc tctgtttcct ttgatgacgc     2040

tttgaaataa aggcaggagt acaagcctaa aaaaaaaaaa aaaaaa                    2086


<210>  2183
<211>  5550
<212>  DNA
<213>  homo sapiens

<400>  2183
atgtctcggc gcaagcaggc caagccccag cacctcaagt cggacgagga gctgctgccg       60

cctgacgggg ctcccgagca cgccgccccg ggggaaggtg cggaggacgc agacagcggg      120

cccgagagcc gcagcggggg cgaggagacc agcgtgtgcg agaaatgctg cgccgagttc      180

ttcaagtggg cggacttcct ggagcaccag cggagctgca ccaagctccc gcccgtgctg      240

atcgtgcacg aggacgcgcc cgcgccgccc cccgaggact tccccgagcc ttcgcccgcc      300

agctccccca gcgagcgcgc cgaaagcgag gcggccgagg aggcgggtgc ggagggcgcg      360

gagggcgagg ccaggccggt ggagaaggag gccgagccca tggacgcgga acccgcgggg      420

gacacgcgcg cgccccggcc cccgcctgcg gcccctgcac ccccaacgcc cgcctacggc      480

gcgcccagca ccaacgtgac cctggaggcg ctgctgagca ccaaggtggc ggtggcgcag      540

ttctcgcagg gcgcgcgcgc ggcaggcggc tcgggagcag gtggaggcgt ggcagctgca      600

gccgtgcccc tgatcctgga acagctcatg gccctgcagc agcagcagat ccaccagctg      660

cagctcatcg agcagatccg cagccaggtg gccctcatgc agcgcccgcc gccgcggccc      720

tcactcagcc ccgcggccgc cccgagcgca ccgggcccgg cccccagcca gctgcccggg      780

ctggccgcgc tcccgctgtc ggccggggcc cctgccgccg ccatcgcggg ctcgggcccc      840

gccgccccgg ccgccttcga gggcgcgcag ccgctgtccc ggcccgagtc tggcgccagc      900

acccccggcg gccctgcgga gcccagcgcg cccgccgccc ccagcgccgc ccctgccccc      960

gctgcccccg ccccggcgcc agcgccgcag agcgcagcct cgtcgcagcc gcagagcgca     1020

tccacgccgc ctgccctggc cccggggtcc ctgctgggtg cggcgcccgg cctgccaagt     1080

ccgcttctac ctcagacttc cgccagcggc gtcatcttcc ccaacccgct ggtcagcatc     1140

gcggccacgg ccaacgctct ggacccgctg tccgcgctca tgaagcaccg caagggcaag     1200

ccgcccaatg tgtcggtgtt cgagcccaaa gccagcgccg aggacccgtt cttcaagcac     1260

aaatgccgct tctgcgccaa ggtcttcggc agcgacagcg cgctccagat ccacctgcgc     1320

tcgcacacag gcgagcggcc cttcaagtgc aacatctgcg ggaaccgctt ctccaccaaa     1380

ggcaacctga aggtgcactt ccagaggcac aaggagaagt acccccacat ccagatgaac     1440

ccttacccgg tccccgagta cctggacaac gtgcccacct gctcgggcat cccctacggc     1500

atgtcgctgc cccccgagaa gcccgtgacc acctggctgg acagcaagcc cgtgctgccc     1560

accgtgccca cgtccgtggg gctgcaactg ccgcccactg tccctggcgc gcacggctac     1620

gccgactctc ccagcgccac cccagccagc cgctccccgc agaggccctc gcccgcctcc     1680

agcgagtgcg cctccttgtc cccaggcctc aaccacgtgg agtccggcgt gtcggccacc     1740

gccgagtccc cacagtcgct cctcggcggg ccgcccctca ctaaagccga gcccgtcagc     1800

ctgccctgca ccaacgccag ggccggggac gctcccgtgg gcgcgcaggc tagcgctgca     1860

cccacatcgg tggacggcgc acccacgagc ctcggcagcc ccgggctgcc cgccgtctcc     1920

gagcagttca aggcccagtt tccgttcggg gggctgctag actcgatgca aacgtcggaa     1980

acctcgaagc tgcagcagct ggtggagaac atcgacaaga agatgacgga cccgaaccag     2040

tgcgtcatct gccaccgggt gctgagctgc cagagcgcgc tgaagatgca ctaccggacg     2100

cacacggggg agcggccgtt caagtgcaag atctgcggcc gcgccttcac caccaagggc     2160

aacctcaaga cgcacttcgg cgtgcaccgt gcaaagccgc ccctgcgcgt gcagcactcc     2220

tgccccatct gccagaagaa gttcaccaac gccgtggtcc tgcagcagca catccgcatg     2280

cacatgggcg gccagatccc caacacgccg ctgccggagg gcttccagga tgccatggac     2340

tccgagctgg cctacgacga caagaacgcg gagaccctga gcagctacga tgacgacatg     2400

gacgagaact ccatggagga cgacgctgag ctgaaggacg cggccaccga cccggccaag     2460

ccactcctgt cctacgcggg gtcctgcccg ccctccccgc cctcggtcat ctccagcatt     2520

gccgccctgg agaaccagat gaagatgatc gactcggtca tgagctgcca gcagctgacc     2580

ggcctcaagt ccgtggagaa cgggtccggg gagagtgacc gcctgagcaa cgactcctcg     2640

tcggccgtgg gcgacctgga gagccgcagc gcgggcagcc ccgccctgtc cgagtcctcg     2700

tcctcgcagg ccctgtcgcc ggcccccagc aatggtgaga gcttccgctc caagtccccg     2760

ggcctgggcg ccccggagga gccccaggaa atcccgctca agaccgagag gccggacagc     2820

ccagccgccg ccccgggcag cggaggcgcc cctggccgcg cgggcatcaa ggaggaggcg     2880

cccttcagcc tgctgttcct gagcagggag cggggtaagt gtcccagcac tgtgtgtggt     2940

gtctgtggca agccttttgc ttgcaagagc gcgttggaaa tccactaccg cagccatact     3000

aaggagcggc cattcgtctg cgcgctctgc aggcgagggt gctccactat gggtaattta     3060

aaacagcact tactgacaca cagattgaaa gagctgcctt ctcagttatt tgaccccaac     3120

tttgctctag gtcccagcca aagcactcct agcctgatct ccagcgccgc acccaccatg     3180

atcaaaatgg aagtgaacgg tcacggcaag gccatggcgc tgggcgaggg tcccccgctg     3240

cccgcgggcg tccaggtccc cgccgggcct cagacagtga tgggcccggg cctggcgccc     3300

atgctggccc ccccaccgcg ccggacgccc aagcagcaca actgccagtc gtgcgggaag     3360

accttctcct cggccagcgc cctgcagatc catgagcgca cgcacaccgg cgagaagccg     3420

ttcggctgca ccatctgcgg ccgggccttc accactaagg gcaacctcaa ggtgcacatg     3480

gggacacaca tgtggaataa cgcccccgcg agacgcggcc gccgcctgtc tgtggagaac     3540

cccatggctc tcctaggggg tgatgccctg aagttctctg aaatgttcca gaaggacctg     3600

gcagctcggg caatgaacgt cgaccccagt ttttggaacc agtatgctgc agccatcact     3660

aacgggctcg ccatgaagaa caacgagatc tccgtcatcc agaacggcgg catcccccag     3720

ctccccgtga gtcttggggg cagcgccctc ccccctctgg gcagcatggc cagtgggatg     3780

gacaaagcac gcactggcag tagcccaccc atcgtcagct tggacaaagc gagctcagaa     3840

acagcagcca gccgcccatt cacgcggttt atcgaggata acaaggagat tggtatcaac     3900

tagccagtga ctcgctcatc tgccctgccc aggcccacgt tttgaagttg gagcatcagg     3960

cctccgacct ttcttgcctc ggttctcatt acactttcac ccatagcaga aaacactttg     4020

tgcggctgcc gagaggtggt cttgtaagcg ctgcatggcg ctcccttcaa cagcaagcct     4080

gactgttctc gagaactctg caatctttta aataagcttc cttcaaaaaa aaaagtgctt     4140

ggaaaaccgc cttaggaaca gaaagagctc agaccatgtc cacttccttt ctcctgaaac     4200

ctaataatct ctccgaggga gaaaggggtt ctctgcggta ttccagtgaa actcatttga     4260

tggtttcttt tgaattagtt agacacttga acggtgtttt ttagaactct tcatgttaaa     4320

gacgtggttt agtactccca atgctgtgta tcatgacact atcttcgtct gtagtattta     4380

tgatgttaag ataatgcggg taacagacaa tataatagcc ccgaccttaa acgaagcttt     4440

tgtactgcag aatacatctg gctgtgtgat tttttttttt aagcaagatt tgttttacta     4500

taaataagtg gattatttca atgcaggcaa aattgtgaag ttctgttggg aaagatagca     4560

tgcttttcgt gtgcaagtac ctgtcagtaa taagcctttt tttttttttt ttttaattta     4620

aatgtttgta gctgctatgt ggacagttgt tttctagtgt ggtctgtagc ccaataactg     4680

gggaacgagt tacagacaaa catcaccgta aatgactcac aacattataa acagttgtga     4740

gaaaatattt cacattatca aagctgtaca ataaaaaggt aatgtttgta taatgtggtt     4800

gcaaactctt aatttatact attgcacttt tagtattttg tattagggag gtttgtctat     4860

aatttgaaaa tttaaaaaaa tgtaaagtat tttataaata gtacttcagt ttaaggaaaa     4920

tgggaaaact gttacagttc cttgttttgt cttatggtca aacaatatta gaaatctctg     4980

ccacttgaaa agccaccaag acttgtcagc ttttcagtaa agtagggcct gccgtttctt     5040

aaattaaaat gatttattta acttttccac aaagcccact ttaaaactgt gaccgccccc     5100

taacgaaacc ttggtgaatt catcctagga ctatgacgtc agtacaagcc aggaaggaac     5160

taggataacc ttctgcaggt ctgattttca tgtaagcggg tctgtctctc tctctcaccc     5220

acagacaaga ttgtggctgc ctggtggcac tggtcacatg tacagtaaac ccaagagaaa     5280

tggcaagtat caggcagtac aatcagtcat gactttgaaa ttttccgagt tcctgattta     5340

tttattatct tctcagatga aagcaaagca cagtgtcctc tgatttttca gaacacagcc     5400

tgacgctgat ggctgagctg catccagcca ggagggcccc ggaggctggg gcggccgagg     5460

cagcacaaac acggcgtcgt gaactacctc attttcgtgc gttgcaagtg tgctggcgtc     5520

tgacactatg aacttccaac aacaaaattg                                      5550


<210>  2184
<211>  5887
<212>  DNA
<213>  homo sapiens

<400>  2184
gaagttgagc aaacacctcc tacttcccgg ccttccatcc cagtttcttc taggaattcg       60

gagcctcccc tgcagcgact cggaagattc gaggcggcgg gggacaagtc ggcgccccag      120

agcggacgag tcaccaggtg tcaagatgct gcaagtacat aggactggac tgggcaggct      180

gggggtcagc ctctccaagg gtcttcacca caaagctgtg ttggccgtcc ggagggagga      240

tgtgaacgcc tgggagagaa gggccccgct agctcccaag cacatcaaag gcatcaccaa      300

tctgggatac aaggtcttga tacagccttc gaatcggcgg gccattcatg ataaggacta      360

tgtcaaagct ggtggcattc ttcaggagga tatttctgaa gcttgtctaa ttttaggagt      420

taaaagacct ccagaggaaa aattaatgtc caggaagact tatgcatttt tctcccacac      480

aataaaagct caggaggcca atatgggctt gttggatgag attctaaaac aggaaattcg      540

ccttattgat tatgagaaaa tggtggatca tagaggagta cgggtagtgg catttggaca      600

gtgggctggt gtggcaggaa tgatcaacat tttacatgga atgggtttaa ggctccttgc      660

tttgggacat cacacacctt ttatgcacat tggcatggct cataactaca ggaatagcag      720

tcaggctgtg caagctgtcc gtgatgctgg ctatgaaata tctttgggtt tgatgcctaa      780

gtcaatagga cccttaacat ttgtgttcac aggaactggt aatgtttcta agggagccca      840

agcaatcttt aatgagctac cttgtgaata tgtggagccc catgaattaa aagaagtttc      900

ccaaactgga gacctcagaa aagtgtatgg gacggtgtta agtcgtcatc atcatcttgt      960

caggaaaaca gatgctgtgt atgatcctgc agagtatgac aaacatccgg agcgctacat     1020

aagtcgtttt aatactgata ttgcacccta tacaacttgc ttaattaatg gaatctactg     1080

ggaacaaaac actcctcgcc tcctaacccg ccaagatgct cagagtctcc tggctccggg     1140

caagttctca cctgctggtg tggaaggctg ccctgcatta ccacacaaac tcgtggcaat     1200

atgtgacatt tcagctgaca caggagggtc tatagagttt atgactgagt gtacaacaat     1260

agagcatccc ttttgcatgt atgatgcaga ccagcatatt attcatgaca gtgttgaagg     1320

ctcggggatc ctgatgtgtt ccattgacaa tttgccggca cagctcccaa ttgaagctac     1380

agaatgcttt ggagacatgc tttaccctta tgttgaagaa atgatattat cagacgcgac     1440

acagcctctt gaaagtcaga atttttctcc tgtggtgaga gatgcagtga ttacatccaa     1500

cggtacatta cctgataaat ataaatatat ccagacactc cgggagagca gggaacgtgc     1560

tcagtcactt tcaatgggca ccaggagaaa ggttttggtt cttggatctg gctacatatc     1620

tgagcctgta ttagaatatt tatcaagaga tggcaatata gaaataacag taggatctga     1680

catgaagaat caaattgaac agttaggcaa gaaatataat attaatcctg ttagcatgga     1740

catttgtaaa caagaagaga agctgggctt cttggtggca aaacaggatc ttgtcatcag     1800

cttgttgcct tatgtattgc accctcttgt ggccaaggcc tgcatcacaa acaaagttaa     1860

catggtcact gcaagctaca tcacaccagc actaaaagaa ttggaaaaga gtgtggaaga     1920

tgctggcatc acaatcattg gtgaattggg attggaccct ggtctggatc acatgttagc     1980

aatggaaaca atagataaag ccaaggaagt gggagccacg attgaatcat atatttccta     2040

ctgtggtggg cttccagccc ctgaacattc aaacaatcca ttgagatata aatttagctg     2100

gagtccagtg ggagttttga tgaatgtaat gcagtctgcc acctatctgc tcgatggaaa     2160

ggttgtgaat gttgcaggag gcatctcctt tcttgatgcc gttacgtcca tggatttttt     2220

tccaggatta aatttggaag gctatcctaa cagagacagt acgaaatatg ctgagattta     2280

tggcatttct tctgctcaca ctttgttgcg ggggacactg agatataagg gatatatgaa     2340

agctttgaat ggatttgtaa aattaggtct tataaacaga gaagcgcttc ctgcctttag     2400

acctgaggcc aaccctctca cctggaaaca actcctctgt gacctagttg ggatttcacc     2460

ctcctctgag catgatgtgt tgaaggaagc tgttcttaag aaactaggag gagacaatac     2520

ccagttggag gctgctgaat ggttgggctt acttggggat gaacaagttc ctcaggcaga     2580

gtccattctg gatgccctct ccaagcattt ggtcatgaag ctttcctatg gtcctgaaga     2640

aaaagatatg attgtgatga gagacagctt tggaatcaga catccttctg gacatttaga     2700

acataaaacg attgatcttg tggcttatgg ggacatcaat ggcttttcag ccatggctaa     2760

aaccgtgggg ttacccaccg ccatggcagc caaaatgttg cttgatggtg aaattggagc     2820

caaaggccta atggggccct tttcaaagga gatctatgga ccaatattgg agcgaattaa     2880

agcagaaggc attatatata ctacacagag tacaattaaa ccataattgg gaattatatt     2940

ttgttttttt cttcccaggc aatacacctc tgaacatgtg tgtgataaat gggtttgcta     3000

atgtgctgtt ttaaagtata aagcataata tgttttggtt aacacaatgt actttttgaa     3060

ctataaatct ttattttaat atggaaatgt ttggaacagg agatgcaagc cactaacaga     3120

gaactttaat aattctaccc tgtattttat aaatacgtat gtgaaagtga tgatcatgct     3180

atttgttaat ttattgtgcc actttttttc ttttgttttt tttttgttgt tgttgttttt     3240

tgagatggag tctcgctctg tcacccaggc tggagtgcag tggcgcgatc tcggctcact     3300

gcaagctccg cctcctgggt tcacgccatt ctcctgcctc agcctcccaa gtagctggga     3360

ctacaggcac ccgccaccac gcccggctaa attttttgta tttttcagta gagacggggt     3420

ttcaccatgt tagccaggat gtccactttt ttcttaaatg aacatattgt cttataacca     3480

gcaaatgaag ttttactttt ttagtcagaa aaaatttcgt cataaagcta tatttttata     3540

tttttaaaat tgatacagtt agataccttc agattaccta agttaagttt ttgccaaaat     3600

gctattttat gccctttttg taaagttatg atttattttg taaatatagt tccttatagt     3660

tttctcttga gtgtttggac atgagaatag ataagattaa attacaattt acaagatcac     3720

ttcattaggc acaggaaaag tatttaacaa aattcaacac cctttcacaa taaaaaataa     3780

aaaataaaaa accctcaaca aactaggaat agaaggaaac ttcctcaacc tgataaaggg     3840

catctatgaa gaacccatgg ttagcatcat acttaatggt gaaggactgg attatttccc     3900

cctgagatca gaaacaagac aaggatgtct gctttggcca tttctattca acttgtactg     3960

gacagtcaag aaagggcaat taggcaagaa aataaaataa aagtcatcta ggttggaaag     4020

gaagaagtat aactaaatag agatgggaga cgatatggtg gttttgtgca tagtaatcca     4080

agggaaaact atagaaaatc caaaggcatg atttattaat aaataaattc agcaaagtta     4140

caggatacag gattaaatat gcagaaattg gttatctttc aatatagtat caatgaataa     4200

atcaaaaatg atgttaagaa aacaatttaa ttttcaacaa tggtcaagct tggtggcttg     4260

tgcctgtaat cccaacactt tgggagtctg aggcagaaag actgctagag gccaggagac     4320

cagcctggga aacagtgaga tcccatctct acaaaaacaa acaaacaaaa aacaacaagc     4380

aaacaaaaaa cagctggatg tgatgacact catctgtcgt ctcagctact cagaggctga     4440

ggtgtaagga tggcttgagc cccaaagttc gaagctgcaa tgagctataa ctgggtcact     4500

gcaatccagc ctggatgaca gagttagacc ttgactcaaa aaaaacaaaa aagaaaagaa     4560

aaaaattgac agcatcagaa agagtaaaat accaatataa ttgagggtcc agaaatattg     4620

atcacattta tcatcaactg acttttgaaa atagtgctaa gacaattcaa tgggggcaaa     4680

atagtctttt tcattaaatg atgcttggaa acatggatat ccacatgcaa aataatgaaa     4740

ttggactcct acctcatatt gcatataaaa attaactcaa agttgaccta agatctaaat     4800

gtaagagcta atattgtaag tatcttcaaa gaaaacatgg cgtaaatctt tctgactttg     4860

aattaggcaa tgatttctta aataaatgac actaaaaaca caagcaacaa aagaagaaaa     4920

taggtaaatt aaaattaaaa ccatttgtgt ttccaaggac aatatcaaga aagcaaaaat     4980

acaacccaca gaatgagata atttttttta aaatcatgta ttagttaagg gaggaatttg     5040

tatttagaat atgtaaagaa ctgttacaat aataattaaa aggcatataa ttcaattttt     5100

aaaaatcaac aagagatctg aattaacagt tctccaaaga agatacacaa aaggccaata     5160

agcacatgaa aaggttctca acatcactag ccatcaggga aatgcaaatg agatctacaa     5220

tgagatatca cttaacactc actggaatag atatataatc aaagtgataa tatcaagtgt     5280

tggtgaggat gcagagaaat tggaaccctc atgcactgtt ggtggatacc cacgtgatat     5340

aaaaacaaat gtctacacaa aaacttgtgc acagatgttc tttgcagcat tatttataat     5400

agcccaaaat tgaaacagcc ctaatttcta tcaactaaca agtgaataaa caaaacgtgg     5460

catatccata caaggaatat tattcagcaa taaaaaaaga gatgaagtac tgatatgcac     5520

cacaacatgg aaaaaccttg aaaacatatc aagtgaagaa tgccagacat gaaaggccac     5580

atattatatg atttcattta tatgaaatgt ccagaacagg cgaatatata tagagagaag     5640

gcagattagt ggttgcttag gctgaagggt tggggaggac aaaggggtga ctgctaatta     5700

gtatggggtt tcttttttgg ggtgatgtaa acgttgtaaa gttgattgtg gtaatggtgg     5760

cacaactctg aatatactaa aaaccactga attgtatact ttgaatgttt gaactgtgtg     5820

gtatgtagat tttatctcaa gttgttataa aaaattaaat tacaaatgca aaaaaaaaaa     5880

aaaaaaa                                                               5887


<210>  2185
<211>  3070
<212>  DNA
<213>  homo sapiens

<400>  2185
aaagcaggcc tgtcccttta agggggttgg ctgtcaatca gaaagccctt ttcattgcag       60

gagaagagga caaagatact cagagagaaa aagtaaaaga ccgaagaagg aggctggaga      120

gaccaggatc cttccagctg aacaaagtca gccacaaagc agactagcca gccggctaca      180

attggagtca gagtcccaaa gacatgggct tgttagagtg ctgtgcaaga tgtctggtag      240

gggccccctt tgcttccctg gtggccactg gattgtgttt ctttggggtg gcactgttct      300

gtggctgtgg acatgaagcc ctcactggca cagaaaagct aattgagacc tatttctcca      360

aaaactacca agactatgag tatctcatca atgtgatcca tgccttccag tatgtcatct      420

atggaactgc ctctttcttc ttcctttatg gggccctcct gctggctgag ggcttctaca      480

ccaccggcgc agtcaggcag atctttggcg actacaagac caccatctgc ggcaagggcc      540

tgagcgcaac ggtaacaggg ggccagaagg ggaggggttc cagaggccaa catcaagctc      600

attctttgga gcgggtgtgt cattgtttgg gaaaatggct aggacatccc gacaagtttg      660

tgggcatcac ctatgccctg accgttgtgt ggctcctggt gtttgcctgc tctgctgtgc      720

ctgtgtacat ttacttcaac acctggacca cctgccagtc tattgccttc cccagcaaga      780

cctctgccag tataggcagt ctctgtgctg atgccagaat gtatggtgtt ctcccatgga      840

atgctttccc tggcaaggtt tgtggctcca accttctgtc catctgcaaa acagctgagt      900

tccaaatgac cttccacctg tttattgctg catttgtggg ggctgcagct acactggttt      960

ccctgctcac cttcatgatt gctgccactt acaactttgc cgtccttaaa ctcatgggcc     1020

gaggcaccaa gttctgatcc cccgtagaaa tccccctttc tctaatagcg aggctctaac     1080

cacacagcct acaatgctgc gtctcccatc ttaactcttt gcctttgcca ccaactggcc     1140

ctcttcttac ttgatgagtg taacaagaaa ggagagtctt gcagtgatta aggtctctct     1200

ttggactctc ccctcttatg tacctctttt agtcattttg cttcatagct ggttcctgct     1260

agaaatggga aatgcctaag aagatgactt cccaactgca agtcacaaag gaatggaggc     1320

tctaattgaa ttttcaagca tctcctgagg atcagaaagt aatttcttct caaagggtac     1380

ttccactgat ggaaacaaag tggaaggaaa gatgctcagg tacagagaag gaatgtcttt     1440

ggtcctcttg ccatctatag gggccaaata tattctcttt ggtgtacaaa atggaattca     1500

ttctggtctc tctattacca ctgaagatag aagaaaaaag aatgtcagaa aaacaataag     1560

agcgtttgcc caaatctgcc tattgcagct gggagaaggg ggtcaaagca aggatctttc     1620

acccacagaa agagagcact gaccccgatg gcgatggact actgaagccc taactcagcc     1680

aaccttactt acagcataag ggagcgtaga atctgtgtag acgaaggggg catctggcct     1740

tacacctcgt tagggaagag aaacagggtg ttgtcagcat cttctcactc ccttctcctt     1800

gataacagct accatgacaa ccctgtggtt tccaaggagc tgagaataga aggaaactag     1860

cttacatgag aacagactgg cctgaggagc agcagttgct ggtggctaat ggtgtaacct     1920

gagatggccc tctggtagac acaggataga taactctttg gatagcatgt ctttttttct     1980

gttaattagt tgtgtactct ggcctctgtc atatcttcac aatggtgctc atttcatggg     2040

gtattatcca ttcagtcatc gtaggtgatt tgaaggtctt gatttgtttt agaatgatgc     2100

acatttcatg tattccagtt tgtttattac ttatttgggg ttgcatcaga aatgtctgga     2160

gaataattct ttgattatga ctgtttttta aactaggaaa attggacatt aagcatcaca     2220

aatgatatta aaaattggct agttgaatct attgggattt tctacaagta ttctgccttt     2280

gcagaaacag atttggtgaa tttgaatctc aatttgagta atctgatcgt tctttctagc     2340

taatggaaaa tgattttact tagcaatgtt atcttggtgt gttaagagtt aggtttaaca     2400

taaaggttat tttctcctga tatagatcac ataacagaat gcaccagtca tcagctattc     2460

agttggtaag cttccaggaa aaaggacagg cagaaagagt ttgagacctg aatagctccc     2520

agatttcagt cttttcctgt ttttgttaac tttgggttaa aaaaaaaaaa agtctgattg     2580

gttttaattg aaggaaagat ttgtactaca gttcttttgt tgtaaagagt tgtgttgttc     2640

ttttccccca aagtggtttc agcaatattt aaggagatgt aagagcttta caaaaagaca     2700

cttgatactt gttttcaaac cagtatacaa gataagcttc caggctgcat agaaggagga     2760

gagggaaaat gttttgtaag aaaccaatca agataaagga cagtgaagta atccgtacct     2820

tgtgttttgt tttgatttaa taacataaca aataaccaac ccttccctga aaacctcaca     2880

tgcatacata cacatatata cacacacaaa gagagttaat caactgaaag tgtttccttc     2940

atttctgata tagaattgca attttaacac acataaagga taaactttta gaaacttatc     3000

ttacaaagtg tattttataa aattaaagaa aataaaatta agaatgttct caatcaaaaa     3060

aaaaaaaaaa                                                            3070


<210>  2186
<211>  6628
<212>  DNA
<213>  homo sapiens

<400>  2186
ctcctcggtg caacctatat aaggctcaca gtctgcgctc ctggtacacg cgcttcaact       60

tcggttggtg tgtgtcgaag aaacctgact gcgccctgag gagaacagcg gagaaggtcc      120

accgagcctg gcgaaaggtc cgctgagcgg gctgtcgtcc ggagccactc cgggctgcgg      180

agcacccagt ggagaccgcg cctggctcag gtgtgggacc ccatccttcc tgtcttcgca      240

gaggagtcct cgcgtgaaat aagcgggttt tgaaaacaaa aaaaagaagg agtggaagag      300

ggggccagga tccaggcctc catccccaca gaagtgaagc tacagctggg aggtctcctc      360

ccaccccaac cgtcaccctg ggtcccgact gcccacctcc tcctcctccc cctcccccca      420

acaacaacaa caacaacaac tccaagcaca ccggccataa gagtgcgtgt gtccccaaca      480

tgaccgaacg aagaagggac gagctctctg aagagatcaa caacttaaga gagaaggtca      540

tgaagcagtc ggaggagaac aacaacctgc agagccaggt gcagaagctc acagaggaga      600

acaccaccct tcgagagcaa gtggaaccca cccctgagga tgaggatgat gacatcgagc      660

tccgcggtgc tgcagcagct gctgccccac cccctccaat agaggaagag tgcccagaag      720

acctcccaga gaagttcgat ggcaacccag acatgctggc tcctttcatg gcccagtgcc      780

agatcttcat ggaaaagagc accagggatt tctcagttga tcgtgtccgt gtctgcttcg      840

tgacaagcat gatgaccggc cgtgctgccc gttgggcctc agcaaagctg gagcgctccc      900

actacctgat gcacaactac ccagctttca tgatggaaat gaagcatgtc tttgaagacc      960

ctcagaggcg agaggttgcc aaacgcaaga tcagacgcct gcgccaaggc atggggtctg     1020

tcatcgacta ctccaatgct ttccagatga ttgcccagga cctggattgg aacgagcctg     1080

cgctgattga ccagtaccac gagggcctca gcgaccacat tcaggaggag ctctcccacc     1140

tcgaggtcgc caagtcgctg tctgctctga ttgggcagtg cattcacatt gagagaaggc     1200

tggccagggc tgctgcagct cgcaagccac gctcgccacc ccgggcgctg gtgttgcctc     1260

acattgcaag ccaccaccag gtagatccaa ccgagccggt gggaggtgcc cgcatgcgcc     1320

tgacgcagga agaaaaagaa agacgcagaa agctgaacct gtgcctctac tgtggaacag     1380

gaggtcacta cgctgacaat tgtcctgcca aggcctcaaa gtcttcgccg gcgggaaact     1440

ccccggcccc gctgtagagg gaccttcagc gaccgggcca gaaataataa ggtccccaca     1500

agatgatgcc tcatctccac acttgcaagt gatgctccag attcatcttc cgggcagaca     1560

caccctgttc gtccgagcca tgatcgattc tggtgcttct ggcaacttca ttgatcacga     1620

atatgttgct caaaatggaa ttcctctaag aatcaaggac tggccaatac ttgtggaagc     1680

aattgatggg cgccccatag catcgggccc agttgtccac gaaactcacg acctgatagt     1740

tgacctggga gatcaccgag aggtgctgtc atttgatgtg actcagtctc cattcttccc     1800

tgtcgtccta ggggttcgct ggctgagcac acatgatccc aatatcacat ggagcactcg     1860

atctatcgtc tttgattctg aatactgccg ctaccactgc cggatgtatt ctccaatacc     1920

accatcgctc ccaccaccag caccacaacc gccactctat tatccagtag atggatacag     1980

agtttaccaa ccagtgaggt attactatgt ccagaatgtg tacactccag tagatgagca     2040

cgtctaccca gatcaccgcc tggttgaccc tcacatagaa atgatacctg gagcacacag     2100

tattcccagt ggacatgtgt attcactgtc cgaacctgaa atggcagctc ttcgagattt     2160

tgtggcaaga aatgtaaaag atgggctaat tactccaacg attgcaccta atggagccca     2220

agttctccag gtgaagaggg ggtggaaact gcaagtttct tatgattgcc gagctccaaa     2280

caattttact atccagaatc agtatcctcg cctatctatt ccaaatttag aagaccaagc     2340

acacctggca acgtacactg aattcgtacc tcaaatacct ggataccaaa cataccccac     2400

atatgccgcg tacccgacct acccagtagg attcgcctgg tacccagtgg gacgagacgg     2460

acaaggaaga tcactatatg tacctgtgat gatcacttgg aatccacact ggtaccgcca     2520

gcctccggta ccacagtacc cgccgccaca gccgccgcct ccaccaccac caccgccgcc     2580

gcctccatct tacagtaccc tgtaaatacc tgtcatgtcc ttcaggatct ctgccctcaa     2640

aatttattcc tgttcagctt ctcaatcagt gactgtgtgc taaattttag gctactgtat     2700

cttcaggcca cctgaggcac atcctctctg aaacggctat ggaaggttag ggccactctg     2760

gactggcaca catcctaaag caccaaaaga ccttcaacat tttctgagag caacagagta     2820

tttgccaata aatgatctct catttttcca ccttgactgc caatctaact aaaataatta     2880

ataagtttac tttccagcca gtcctggaag tctgggtttt acctgccaaa acctccatca     2940

ccatctaaat tataggctgc caaatttgct gtttaacatt tacagagaag ctgatacaaa     3000

cgcaggaaat gctgatttct ttatggaggg ggagacgagg aggaggagga catgactttt     3060

cttgcggttt cggtaccctc tttttaaatc actggaggac tgaggcctta ttaaggaagc     3120

caaaattatc ggtgcagtgt ggaaaggctt ccgtgatcct ctcgctgcac ccttagaaac     3180

ttcaccgtct tcaaactcca tttccatggt tctgttaatt ctcaaggagc agcaactcga     3240

ctggttctcc caggagcagg aaaaaccctt gtgacatgaa acatctcagg cctgaaaaga     3300

aagtgctctc tcagatggac tcttgcatgt taagactatg tcttcacatc atggtgcaaa     3360

tcacatgtac ccaatgactc cggctttgac acaacacctt accatcatca tgccatgatg     3420

gcttccacaa agcattaaac ctggtaacca gagattactg gtggctccag cgttgttaga     3480

tgttcatgaa atgtgaccac ctctcaatca cctttgaggg ctaaagagta gcacatcaaa     3540

aggactccaa aatcccatac ccaactctta agagatttgt cctggtactt cagaaagaat     3600

tttcatgagt gttcttaatt ggctggaaaa gcaccagctg acgttttgga agaatctatc     3660

catgtgtctg cctccatatg catctgggca tttcatcttc agtcccctca ttagactgta     3720

gcattaggat gtgtggagag aggagaaatg atttagcacc cagattcaca ctcctatgcc     3780

tggaaggggg acatctttga agaagaggaa ttagggctgt ggacactgtc ttgaggatgt     3840

ggacttcctt agtgagctcc acattacttg atggtaacca cttcaaaagg atcagaatcc     3900

acgtaatgaa aaaggtccct ctagaggatg gagctgatgt gaagctgcca atggatgaaa     3960

agcctcagaa agcaactcaa aggactcaaa gcaacggaca acacaagagt tgtcttcagc     4020

ccagtgacac ctctgatgtc ccctggaagc tttgtgctaa cctgggactg cctgacttcc     4080

tttagcctgg tcccttgcta ctaccttgaa ctgttttatc taacctctct ttttctgttt     4140

aattctttgc tactgccatt gaccctgctg caggatttgt gtcattttcc tgcctggttg     4200

ctgagactcc attttgctgc cacacacaga gatgtaagag gcaggcttta attgccaaag     4260

cacagtttga gcagtagaaa acaacatggt gtatatctca aattgcctga catgaagagg     4320

agtctaacgg tgaagtttca cttttcatca gcatcatctt tcacatgttc attatcatct     4380

gctcttattc ttgcatgttt aaacacttaa aatttttagt ataattttta gtgtgttttg     4440

aagtggtgac taggctttca aaaacttcca ttgaattaca aagcactatc cagttcttat     4500

tgttaaacta agtaaaaatg ataagtaaca tagtgtaaaa tattccttta ctgtgaactt     4560

cttacaatgc tgtgaatgag aggctcctca gaactggagc atttgtataa taattcatcc     4620

tgttcatctt caattttaac atcatatata atttcaattc tatcaattgg gcctttaaaa     4680

atcatataaa aggatataaa atttgaaaag agaaacctaa ttggctattt aatccaaaac     4740

aacttttttt ttccttcaat ggaatcagaa agcttgtcaa tcactcatgt gttttagagt     4800

aattactttt aaaatggtgc atttgtgctt ctgaactatt ttgaagagtc acttctgttt     4860

acctcaagta tcaattcatc ctccatacat ttgaattcaa gttgtttttt tgtcaaattt     4920

acagttgtca attgatcttc aagctgcagg gtgcctagaa atgggccgtt gtctgtagcc     4980

ctggcatgtg cacacggaca tttgccacca ctgcaagcaa aagtctggag aagttcacca     5040

acgacaagaa cgattaggga aaatatgctg ctgtgggtta acaactcaga aagtccctga     5100

tccacatttg gctgtttact aaagcttgtg attaactttt tggcagtgtg tactatgctc     5160

tattgctata tatgctatct ataaatgtag atgttaagga taagtaattc taaatttatt     5220

attctatagt tttgaagttt ggttaagttt cctttcactc aattgattta ttttgttgtt     5280

aatcaaattt atgttaattg gatcctttaa attttttttg gcattttcca acaaaaatgg     5340

ctttattcat aagaaaggaa aaaaatcaat ggaatttgat atctaaagaa gttagaaagg     5400

gagcaaaata aaaaacataa aggagataga tgaattagta agcaaatcag tagtcgagtt     5460

tttcaaactg gcaaaattaa ttaattgact tttagcccaa atttacattg ttaattaaat     5520

caagaaggaa gaagatctaa gagctcccat tgataggcaa gcctagagag aactagctaa     5580

atttatcatg ctaggatatt gaaacacaga aagtttacat acatttatga agggtcaatt     5640

tagtttggac agtgaggtat ttgtcttagt ggaaaaaagg agaattagtc tgatcaaatc     5700

gtgaagtaat acagtgaact tgcaggtgca caaaataaga gggccacatc tatatggtgc     5760

agtctggaat tctgtttaag tttgtaggta cctcttggac ttctgaattg atccagttgt     5820

catccaccac agacatctca catcagatac agacagttcc aagattgaca acagagaaca     5880

acctgctgga aagacctggg cagaaatgga gagccctgcg ggaaccatgc tacattttca     5940

tctaaagaga gaatgcacat ctgatgagac tgaaagttct ttgttgtttt agattgtaga     6000

atggtattga attggtctgt ggaaaattgc attgctttta tttctttgtg taatcaagtt     6060

taagtaatag gggatatata atcataagca ttttagggtg ggagggacta ttaagtaatt     6120

ttaagtgggt ggggttattt agaatgttag aataatatta tgtattagat atcgctataa     6180

gtggacatgc gtacttactt gtaacccttt accctataat tgctatcctt aaagatttca     6240

aataaactcg gagggaactg cagggagacc aacttattta gagcgaattg gacatggata     6300

aaaaccccag tgggagaaag ttcaaaggtg attagattaa taatttaata gaggatgagt     6360

gacctctgat aaattactgc tagaatgaac ttgtcaatga tggatggtaa attttcatgg     6420

aagttataaa agtgataaat aaaaaccctt gcttttaccc ctgtcagtag ccctcctcct     6480

accactgaac cccattgccc ctacccctcc ttctaacttt attgctgtat tctcttcact     6540

ctatatttct ctctatttgc taatattgca ttgctgttac aataaaaatt caataaagat     6600

ttagtggtta agtgcaaaaa aaaaaaaa                                        6628


<210>  2187
<211>  3305
<212>  DNA
<213>  homo sapiens

<400>  2187
gcctaacttg cgcgctgaga tttccggcgt gggagcagag gtctgagtct tgcgtgggtc       60

ctctatatag ggtgagaagc gtggcgctcg gttcctgcct cggggaagtc ctggcgcaga      120

tgggccacgg ggccggcgtg gcggcgcctg ggaccgactg aggcctaggc gccggagccg      180

gccgcgcctg ggctggagcg gggctcctcg gcctggactg ggagcccccg gccccgggct      240

cctgctggcg ccgtccaacc ttacatgggt tcagggcgcc ttcgtaggcg ggcacggctg      300

gtttcgggct aaggcgctct ggagacctga cgatggcgtc gggcccgggc tcccaggaac      360

gggaagggct cctgatagtg aagctggagg aggactgcgc ctggagccag gagctgcccc      420

cacctgaccc aggaccgagc cccgaggcct cccacttgcg cttcagacgg ttccgcttcc      480

aagaggcagc tggtccccgg gaagccctca gccggctcca agagctttgc catgggtggc      540

ttcggcctga gatgcgcacg aaggagcaga tcttggagct gctggtgtta gagcagttcc      600

tgaccatcct gccccaggag atccagagca gggtgcagga gctgcatccg gagagcggcg      660

aagaagcggt gacccttgtg gaggatatgc agagagagct tgggagactg agacaacagg      720

tcacaaacca tgggcgggga acagaagtgc ttttggagga gcctttgcct ctggaaacag      780

cacgagagtc accgagcttc aagctggagc caatggagac tgagcgaagc cctggcccca      840

ggctgcagga gctgctaggc cccagccccc aaagggaccc ccaggctgta aaggagaggg      900

cattatctgc tccctggctt tctctttttc ctcctgaagg gaacatggaa gacaaggaga      960

tgactgggcc ccagttgcct gagagcttag aggacgtggc aatgtacatc tcccaggagg     1020

agtgggggca tcaggatcct agtaagaggg ccctctccag ggacacggtg caggagagtt     1080

atgagaatgt ggactcactg gagtctcaca ttcccagtca ggaggtccca ggcacccagg     1140

tgggacaagg aggaaagcta tgggatccca gtgtccagag ctgcaaggag ggcctgagcc     1200

ccagaggccc agctccagga gaagagaaat ttgagaacct ggaaggtgtt ccgtctgtat     1260

gctctgagaa catccaccct caggtgctgc ttcctgacca ggcccgaggg gaggtgccct     1320

ggagtcctga gctgggaaga cctcatgacc ggtcgcaagg ggattgggcg cctcccccag     1380

agggtggaat ggagcaggcc ttggcaggag cctcaagtgg cagagaactg gggcgaccga     1440

aggaactgca gccaaagaaa ctccatttat gtcccttgtg tggcaaaaat ttctctaaca     1500

actcaaacct aattaggcac cagagaatac atgcagctga aagactgtgt atgggtgtgg     1560

actgcactga aatctttggt gggaacccac gtttcctgtc actacacaga gcacacctgg     1620

gagaggaggc ccacaagtgc cttgaatgtg ggaaatgctt cagtcagaac acccatctga     1680

ctcgccacca acgcacccac acgggtgaga agccctatca gtgcaacatt tgcggaaaat     1740

gtttctcctg caactccaac ctccacaggc accagagaac gcacactggg gagaagccct     1800

acaagtgccc tgagtgtggg gagatctttg ctcacagttc caacctcctt cggcaccaga     1860

gaattcacac tggagagcga ccttataagt gtcccgagtg tgggaaaagt ttctctcgga     1920

gttcacacct cgtcattcac gaaagaactc atgagagaga gagactttac cccttctctg     1980

agtgtgggga agctgtgagt gacagcaccc cctttcttac aaaccatgga gcccataagg     2040

cagagaagaa gctctttgaa tgtttgactt gtgggaaaag cttccggcag ggcatgcacc     2100

tcaccagaca tcagagaaca cacacaggag agaaaccgta taaatgtacc ctttgtgggg     2160

aaaacttctc tcatagatcc aatttaatca ggcaccagag aatccacaca ggagaaaaac     2220

cctatacctg tcatgagtgc ggagacagct tctctcacag ctccaatcgg attcgccacc     2280

tgagaacgca tacgggagag agaccctata aatgttctga atgtggagaa agcttctctc     2340

ggagttcccg tcttatgagt catcagagaa ctcacacagg ttagtaacag tggggtttct     2400

ctttgcccca ggtgaggtgg catattcaga ggagcctgtt ggcaagagct ggtattccct     2460

gcccagccga ccaaatgacc tctgcattct tcaggtaatg ggggctcatt gtgagggagg     2520

tgcagaggca gcagaggatt ggcataaaac tgaaaaggag ttctgtctgc atgagaaagg     2580

atggcaagtc tctgaggtga cctcagggtg gaattctctg ttaagtccac cctgccccag     2640

ggtgctccta ccctcttggt ctttttaaag ccaaggtgcg atttgggcac ctgactgtcc     2700

agtttacctt aacaagtttg ggaatccatg tgatgttttt gatacttctt cctcatttgg     2760

gacattcagt aggagcattt gggcttccgg ggcccctgag accaaagaag aggggccaag     2820

taccctggga aatcagctga aggtcaacaa aagactggtt gtgagttgca gctgtcccga     2880

aggccccagt tgggaagcca tgggcagtcc agatcaagcc accacgtgcc ctacgatggc     2940

ctaacaggag tgcccattgg cagattacac atgtaaatat gacctcagac aaaaaggaac     3000

cagaggccca agggcaataa taaggtggaa tttgcaggtc agcccaggaa ttggcagagg     3060

aagtaggtgt ctgataaccc tttgtggaga atgagattcc ccccacctgt gtgagaaaaa     3120

taaacagctc tggagtcttg ttcctgactc cagaggaacg agagcattcc aggaaagaga     3180

gattccctgg aaaattgaaa atgtgaatcc tagggggaaa ttggggattg tgtctttccc     3240

tgttgaaaat gtttggatgg gaataaatat cttcaggaaa cataaaaaaa aaaaaaaaaa     3300

aaaaa                                                                 3305


<210>  2188
<211>  7519
<212>  DNA
<213>  homo sapiens

<400>  2188
agttactgcc ctgacggcgg cggcggcggc ggttggccgg tgggggctgg ggcgagcacg       60

accgattctg ctgggaaagc tggaactggc agccgccggg ggccaagagg aggatccgga      120

gctgggagcg tgccccgggc ccggcggagg aggcggctgc agttggagtg gagtcttggg      180

agcgctgctg gcagcgactt ctcagcgaag caagtgtctg agactgagag tccctaacag      240

cggcagcggc ggccacggcg gcggctgggg ccgaggtgtg ttctactccc tcttctggga      300

atgaagcctc cccagcaaag cctatacctg cttgttgatt ctgttgatga agggtgtaac      360

attactgaag gtgaacaaac gtctaccagc ttatctggga ctgttgcagc acttttagct      420

ggtcaccatg agttctttcc accatggcta ttgcttctct gttctgcccg aaagcagagt      480

aaggctgtta ctaaaatgtt tactggtttt cgaaaaataa gtttagatga ccttcggaag      540

gcatatatcg tcaaggatgt tcagcagtac attcttcatc gtttagatca agaagaagct      600

ttgcgacaac acctcacaaa agaaactgca gagatgttaa atcaactgca cattaaaagc      660

agtggatgct ttctttacct agaacgagtt ttagatggag ttgtagaaaa ttttattatg      720

ttaagagaaa ttcgtgacat cccaggaact ctaaatggtt tatatctctg gctgtgccaa      780

agactttttg taagaaaaca atttgcaaag gttcagccta ttttgaatgt gattcttgca      840

gcctgccgac ctttgaccat aacggaatta tatcacgcag tatggaccaa aaacatgtcg      900

ttaactttgg aagattttca acgcaagtta gatatcctct ccaaacttct tgttgatgga      960

ctaggaaata caaaaatact gtttcattat agttttgccg agtggcttct ggatgtgaaa     1020

cactgtactc agaagtattt atgtaatgca gcagaaggac acagaatgtt ggctatgagt     1080

tatacctgtc aagccaagaa tttaacacca ttggaagcac aagaatttgc attgcactta     1140

attaactcaa acttacaatt agagacagcg gagttagctc tgtggatgat atggaatggt     1200

acacctgtca gagattccct ttctactttg atacccaagg aacaagaagt gctacagctg     1260

ttggttaaag ctggggctca tgtcaacagt gaagacgatc gcacatcatg catagttcga     1320

caagccttag aaagagagga ttccattcgg acattattag ataatggagc ttcagtaaat     1380

cagtgtgatt caaatgggag aacattattg gctaatgctg catatagtgg cagtcttgat     1440

gtagtcaatt tacttgtctc taggggagca gatttagaga tagaagatgc tcatggacat     1500

acaccactca ctctagcggc tagacaggga cataccaagg tggttaattg tttgattggg     1560

tgtggagcaa atattaatca tactgatcaa gatggttgga cagcattaag atctgctgct     1620

tggggtggcc atactgaggt agtttctgca ctactttatg ctggcgtaaa agtggattgt     1680

gcagatgctg atagccgaac agctttgaga gcagcagcat ggggaggaca cgaggatatt     1740

gtactgaatt tgctacaaca tggcgctgaa gtgaacaaag ctgataatga aggtagaact     1800

gctttgatag cagcagcata catgggacat agagagattg tggaacacct actggaccat     1860

ggagcagaag taaatcatga ggatgttgat ggcaggactg cactctctgt agctgcactt     1920

tgtgtgcctg caagtaaagg gcacgcatca gttgttagcc ttttaattga tcgaggtgct     1980

gaagtagatc attgtgataa agatggcatg actccactgc tggtagctgc ctatgaagga     2040

catgttgatg tggttgactt gcttctagaa gggggagcag atgtagatca cacagataac     2100

aatggccgta cacccctctt agcagcagcg tctatgggtc atgcatcagt tgtaaataca     2160

cttttgtttt ggggtgcagc tgtggatagt attgatagtg aaggtaggac agtcctcagt     2220

atagcttcag cacaaggaaa tgttgaggtg gtacgtactc tactggatag agggttagat     2280

gaaaatcaca gagatgatgc tggatggaca cctttgcaca tggcagcttt tgaagggcac     2340

agattgatat gtgaagcact tattgaacaa ggtgctagaa caaatgagat tgacaatgat     2400

ggacgaatcc ctttcatatt agcttcacaa gagggtcatt atgattgtgt tcaaatatta     2460

ctggaaaaca aatccaacat tgatcaaaga ggttatgatg gaagaaatgc actgcgggtt     2520

gctgcattag aagggcacag ggacattgtt gaattgcttt ttagccatgg tgctgatgtt     2580

aactgcaaag atgctgatgg tcggcctaca ctttatatct tggccttaga aaatcagctt     2640

acaatggccg aatatttttt agaaaatggt gcaaacgtag aagcaagtga tgctgaagga     2700

aggacagcac ttcatgtgtc ttgttggcaa ggccatatgg aaatggtgca ggtcctgata     2760

gcataccatg ctgacgtcaa tgctgcagac aatgaaaagc gctctgcttt gcagtctgca     2820

gcctggcagg gccatgtaaa agtggttcag cttctgattg agcatggtgc tgtagttgac     2880

catacatgta accaaggtgc aactgcactc tgtattgcag cccaggaagg gcacattgat     2940

gttgttcagg tcttattaga gcatggtgct gatccaaacc atgctgatca atttggacgc     3000

actgctatgc gtgttgcagc caaaaatgga cattctcaga taattaaatt attagaaaaa     3060

tatggtgcat ctagtttgaa tggctgttcc ccatctcctg ttcacacaat ggagcaaaaa     3120

cctctacagt cattgtcttc aaaagtgcag tcattaacaa ttaaatcaaa tagctctggt     3180

agtactggtg gaggggatat gcagccttcg ttacgtggtt tacctaatgg gcctactcat     3240

gcttttagtt ctccttcaga atctccagat tctacagttg accggcagaa gtcatcactg     3300

tcaaataatt ccctgaaaag ctcaaaaaat tcatctttga gaactacttc atctacagca     3360

acggctcaaa cagtgccaat tgatagcttt cataacttgt catttacaga acaaattcag     3420

cagcattcat tgccacgcag tagaagtcga cagtcaattg tttccccatc ttccacaaca     3480

cagtccttag gacagagtca taattcacca agtagtgaat ttgagtggag tcaagtaaag     3540

cccagtttga agtcaactaa agcaagtaaa ggggggaaat cagaaaattc tgccaagtct     3600

ggatcagctg ggaaaaaagc gaaacaaagt aattcttcac agccaaaggt tttagaatat     3660

gaaatgactc agtttgatag aagaggacct atagccaaat ccgggactgc tgcaccacct     3720

aaacaaatgc cagcagaatc tcaatgcaaa attatgatac cttcagctca gcaggaaatt     3780

ggtcgatctc aacagcagtt tcttattcac caacaaagtg gggaacagaa gaagagaaat     3840

ggaataatga caaatccaaa ttatcatctt cagagcaacc aggtttttct tggtagggtt     3900

tcagtcccac gaacaatgca agatagaggg catcaggaag tgttggaggg atacccttcc     3960

tcagagacag aattaagcct taaacaagct ctgaagcttc agattgaagg ttctgaccct     4020

agcttcaact ataaaaagga aacaccatta taaaagtttc ctattctgtg aaacagaaga     4080

cattgtgatg gagtggttct tcagctactg gatggaaaca tatgcctgtt gatttgctga     4140

aaaaacaaaa aaaatgaaga atgtgatctc tgcagtacag ttaccttaat tactgtaatg     4200

tgcctaaata gtaaggctgc cttctcaatg taaccctctg tgcttaaaaa atttcatttt     4260

gtgtgctttg tattcactac acaggaataa gcacttttta aaaatgcaga tacatactgc     4320

agttccctga taaaagctga aaagaaaatt tgagtatttt aagttaagat gtgataaaaa     4380

atgtgcatgt gccataatca aatatatatg aaaaggcagt gttccttgta tttatttttt     4440

tttctttttg tggcaaaaga aacttaaaca tactgtttca gtcacattgc attgtagtgt     4500

atggcctgtt tcttgtatct ttaaagacgt tgctcaataa aacaaatctt gcaactgttc     4560

tatgttcact acaccttcag cattggataa aaatcatttt ctatataaat atcacattga     4620

aatgaaaaaa tgatttcttg gcagtttaaa aaaaatattt tatagtagtt tagggagctg     4680

ctttaagtag tttaaatctg gattttccca gtagaattct tctcatctct ggctaaacat     4740

gtcagaacaa acaaccaacc agtctgtagg cagaacaaag tcctatttca tccgctggga     4800

tacaatttca tcttccattc actttgtcat tccacctcta agaagacaga ctatcattcc     4860

tgaggcatga aaattctcag ggacaaagcc atgcctcagt cacatgtgtg tgcagagaga     4920

aatgcacctg tctatctaag ggtagatttt tgatccctga ataattcatt gactaaactg     4980

acctcttcct cctggctaaa taaattaatt ttgctggctt ctctctcagc ggtttctatt     5040

ttgtaaattg ctgcatgacc aaaatagccc cactcaaaat caattggatt aattttaatg     5100

gtttggttgg atgaatattc tggatgaata taaaatgtgc tgcccttcac agatgacacc     5160

actcccctgt caatcatagc acatgtgtac tttttattgt tacttaatag tgatggattt     5220

gcacttttct atcctcatac tctttcctgt tttcttcttt gtacaattgc atgcaggagg     5280

gctggatgcc agggttaaga gagaaattca tgacaaggaa ggtaaaattg gttcaaatga     5340

gcatgtgtcc cacagcctta gtctccttac tcttaaatca gtggagctgt agcttagatg     5400

ggtcgtttat atgtctggaa aagttgtcat aacagtttag aagccaaggt tgtggatttg     5460

atcttagaat gggcctgtta atcttataga acccagaaat tctgttcttt tcatgtactg     5520

ttgatgagga atgaggaaag agaatttgga gattcagcac aaaaccattg ctacttctag     5580

aacaaaatct ttagaatatg tcctaataac aaaggtcagt aatgtcatct tcatatatga     5640

aggacacatg tgatacattg ttcgtggaaa tagaaatgta taattatgat aaatgtttca     5700

cttgaatctt attgtaaggc ttttcttgct tttatttttt aaagtcagca aaactcattt     5760

tgtctgtcat ctataagtca tagtgaggac tacgagataa gttgataagt tcaattgata     5820

ttaaggtgac atggcaatat taataactca aatgtgaatg tttcaagtat tgaattcttg     5880

tccctatggg acatttatta aataaaatta atgggactct tgcaaagtag ccttaaaagt     5940

gttaatgagt ctattaataa atatgaacac atactattat tagaaccaac tttactcata     6000

tctcaaatac agtacattta cattactgta gaggatgaag ctctaatttc tattacatgt     6060

aattttcttt agaaagagaa ccctgaaagc tgccagtttt tctattaact ttgaattatt     6120

gaaattgtat ttatttaatt ttattgtttt tacaaaattg caccttgtgt ccaaagggcg     6180

aagatatgac attgcataag ggatttatgt ttttcaaaga gctaactgtt ttcatatcca     6240

tactatatac acttgaagca attggtagga agagaaccta ttggaaaaat acgattttca     6300

aaagtaagta ttcctcggga tgtttttata taaattatgt tttggaatag aacataaatg     6360

actttgagtt aggataagga tgataggatg ggtgctggag atgccctgcc ttgcttattt     6420

gtttctgtgg gggatttaat actataaatg aaaatggctt ctgctccatt aaaaagtaaa     6480

aattgtcctc caaatataaa actccttaat agatattttt gaaattaaaa tctttaaatt     6540

ttataaatca gctgttgcca ctacacaact atgatggcat gtgcttataa catttttata     6600

acattccgtc tgtgtctatt ccctaaatat catgagttta taataaggaa agtgataaaa     6660

atacagtaat gaaataaaaa tctgaatgtt tctaagaaag gttttggaag gaaaaatgac     6720

ctgaaatcag tgcgtactgc aaagtacagc caataatttt tgttctttgt tttcaccccc     6780

accctcactg gaattctcac caaaaatagt ttgatactta aaaaacagaa gtaaatactt     6840

ttctcaatat tgttttggct atgcaaatat ttgttttgct taatgtcctc catttacact     6900

tctcagcaaa tgtagttgca aacaaatgct ttctttttat ttttcccttg gtttgaggta     6960

tgtaaatagc caaaaatgta cattgaattt cacattgtaa aagttttatt ttatcccttg     7020

tatgatatta ctcaaaaaat ccctgtgtat atgaaagtgc ataataaata tatttgcttt     7080

acagagaaga tcttgtttta attttgtcct tgaaccagta gaacatgcat gatatgcata     7140

tagcataaac aactgttagt tgttttaagt tattatctta aataaatcct gagcaaatga     7200

atttggaaac attttgcaaa gaagaaagtg aaatataaca ctgtccaaag gaaggtagaa     7260

aaacaaagat ttactgttta tgtcttccta agccttttta aagacttaat gttcttttcc     7320

cccccgtgac tgattatata ctatatcaca ccatgtcagg ttttgtgcct ctgagaattg     7380

cagtaatcca ataacttttg tatatgtgtg ctccttgatc atcagaatat tatggccatc     7440

ttatggcgga tattttggga gtttattgca aacatggtca ttcattttct aaataaaatt     7500

tgtgtgtttc ttcactcag                                                  7519


<210>  2189
<211>  8802
<212>  DNA
<213>  homo sapiens

<400>  2189
agttactgcc ctgacggcgg cggcggcggc ggttggccgg tgggggctgg ggcgagcacg       60

accgattctg ctgggaaagc tggaactggc agccgccggg ggccaagagg aggatccgga      120

gctgggagcg tgccccgggc ccggcggagg aggcggctgc agttggagtg gagtcttggg      180

agcgctgctg gcagcgactt ctcagcgaag caagtgtctg agactgagag tccctaacag      240

cggcagcggc ggccacggcg gcggctgggg ccgagttact tgtggaaatt gttgattacc      300

cggacgtctt aaaaccaaga aacctgtgaa caggttcatt aagaatctgc tgtcttgaaa      360

aatgcatatt atgaatgctt tgaattaaga aggtgttaac agtggttgtc atttctgcca      420

cataagagac tataatctga aacagttcct ggcagttgcc cagatgcctg aaactggcac      480

gatctagtac tcttgagtga tcatccttca acgagaaata cagagctact tacatactgt      540

acctcatacc gtataaatgt aatctctctg atgccattta atgcagtgga cctcttttca      600

gaatctaatt gtcagatgca gaattaacac ttggaatctg gagaagcatt ttgtacaaat      660

tgaaagattg ggttttttct ttagttttcc acatgtattg tctcatctct gttcttgaaa      720

catccacaat cacataaact ccagttataa ccatggagtt atgtgactca ttaaaattta      780

ggaaaagtgt tgctgagctg tggaatcagg cgtttctccc tcagttcaac aactaataca      840

tagactgctg atcaagaata aggaaccaaa taaagtcatg cacgttctgt tgacagagga      900

actctgtggc tgttgaattt tactgtaact agttactctg tcttcagagt caacttaata      960

tacaagttat gtcataatgg atggaaagac ctgtgttgat gtatccagac tctagcaaat     1020

gaagataaaa aacccgttat gactaatcct tgggaagaga aagtctgcaa aatggctcaa     1080

accagtttac tgcaagggaa gcagttttac tgtagggagt gggttttcca caagcttcag     1140

cattgcctcc aggagaaaag taactgctgc aatagtgctg tcaatgcacc atcacttgta     1200

atgaattctg ggaataatgc tagtggtgtc tctggaaagg gagctgcctg gggtgtgttg     1260

ttggtaggag ggcctggcag tggcaagacg gccctatgta ctgaactctt atggccaagt     1320

tcacctgcaa gtttgcagag aggtttacat cgccaagctt tggcctttca tttctgcaaa     1380

gcccaggact ctgatacttt gtgtgttgga gggtttatta gaggtctagt agcccagatc     1440

tgccgcagtg gactactcca aggatatgag gacaagctaa gggatccagc agtccaaagc     1500

ctcttacagc ctggggagtg cgagagaaac ccagccgaag catttaaaag gtgtgttcta     1560

ctccctcttc tgggaatgaa gcctccccag caaagcctat acctgcttgt tgattctgtt     1620

gatgaagggt gtaacattac tgaaggtgaa caaacgtcta ccagcttatc tgggactgtt     1680

gcagcacttt tagctggtca ccatgagttc tttccaccat ggctattgct tctctgttct     1740

gcccgaaagc agagtaaggc tgttactaaa atgtttactg gttttcgaaa aataagttta     1800

gatgaccttc ggaaggcata tatcgtcaag gatgttcagc agtacattct tcatcgttta     1860

gatcaagaag aagctttgcg acaacacctc acaaaagaaa ctgcagagat gttaaatcaa     1920

ctgcacatta aaagcagtgg atgctttctt tacctagaac gagttttaga tggagttgta     1980

gaaaatttta ttatgttaag agaaattcgt gacatcccag gaactctaaa tggtttatat     2040

ctctggctgt gccaaagact ttttgtaaga aaacaatttg caaaggttca gcctattttg     2100

aatgtgattc ttgcagcctg ccgacctttg accataacgg aattatatca cgcagtatgg     2160

accaaaaaca tgtcgttaac tttggaagat tttcaacgca agttagatat cctctccaaa     2220

cttcttgttg atggactagg aaatacaaaa atactgtttc attatagttt tgccgagtgg     2280

cttctggatg tgaaacactg tactcagaag tatttatgta atgcagcaga aggacacaga     2340

atgttggcta tgagttatac ctgtcaagcc aagaatttaa caccattgga agcacaagaa     2400

tttgcattgc acttaattaa ctcaaactta caattagaga cagcggagtt agctctgtgg     2460

atgatatgga atggtacacc tgtcagagat tccctttcta ctttgatacc caaggaacaa     2520

gaagtgctac agctgttggt taaagctggg gctcatgtca acagtgaaga cgatcgcaca     2580

tcatgcatag ttcgacaagc cttagaaaga gaggattcca ttcggacatt attagataat     2640

ggagcttcag taaatcagtg tgattcaaat gggagaacat tattggctaa tgctgcatat     2700

agtggcagtc ttgatgtagt caatttactt gtctctaggg gagcagattt agagatagaa     2760

gatgctcatg gacatacacc actcactcta gcggctagac agggacatac caaggtggtt     2820

aattgtttga ttgggtgtgg agcaaatatt aatcatactg atcaagatgg ttggacagca     2880

ttaagatctg ctgcttgggg tggccatact gaggtagttt ctgcactact ttatgctggc     2940

gtaaaagtgg attgtgcaga tgctgatagc cgaacagctt tgagagcagc agcatgggga     3000

ggacacgagg atattgtact gaatttgcta caacatggcg ctgaagtgaa caaagctgat     3060

aatgaaggta gaactgcttt gatagcagca gcatacatgg gacatagaga gattgtggaa     3120

cacctactgg accatggagc agaagtaaat catgaggatg ttgatggcag gactgcactc     3180

tctgtagctg cactttgtgt gcctgcaagt aaagggcacg catcagttgt tagcctttta     3240

attgatcgag gtgctgaagt agatcattgt gataaagatg gcatgactcc actgctggta     3300

gctgcctatg aaggacatgt tgatgtggtt gacttgcttc tagaaggggg agcagatgta     3360

gatcacacag ataacaatgg ccgtacaccc ctcttagcag cagcgtctat gggtcatgca     3420

tcagttgtaa atacactttt gttttggggt gcagctgtgg atagtattga tagtgaaggt     3480

aggacagtcc tcagtatagc ttcagcacaa ggaaatgttg aggtggtacg tactctactg     3540

gatagagggt tagatgaaaa tcacagagat gatgctggat ggacaccttt gcacatggca     3600

gcttttgaag ggcacagatt gatatgtgaa gcacttattg aacaaggtgc tagaacaaat     3660

gagattgaca atgatggacg aatccctttc atattagctt cacaagaggg tcattatgat     3720

tgtgttcaaa tattactgga aaacaaatcc aacattgatc aaagaggtta tgatggaaga     3780

aatgcactgc gggttgctgc attagaaggg cacagggaca ttgttgaatt gctttttagc     3840

catggtgctg atgttaactg caaagatgct gatggtcggc ctacacttta tatcttggcc     3900

ttagaaaatc agcttacaat ggccgaatat tttttagaaa atggtgcaaa cgtagaagca     3960

agtgatgctg aaggaaggac agcacttcat gtgtcttgtt ggcaaggcca tatggaaatg     4020

gtgcaggtcc tgatagcata ccatgctgac gtcaatgctg cagacaatga aaagcgctct     4080

gctttgcagt ctgcagcctg gcagggccat gtaaaagtgg ttcagcttct gattgagcat     4140

ggtgctgtag ttgaccatac atgtaaccaa ggtgcaactg cactctgtat tgcagcccag     4200

gaagggcaca ttgatgttgt tcaggtctta ttagagcatg gtgctgatcc aaaccatgct     4260

gatcaatttg gacgcactgc tatgcgtgtt gcagccaaaa atggacattc tcagataatt     4320

aaattattag aaaaatatgg tgcatctagt ttgaatggct gttccccatc tcctgttcac     4380

acaatggagc aaaaacctct acagtcattg tcttcaaaag tgcagtcatt aacaattaaa     4440

tcaaatagct ctggtagtac tggtggaggg gatatgcagc cttcgttacg tggtttacct     4500

aatgggccta ctcatgcttt tagttctcct tcagaatctc cagattctac agttgaccgg     4560

cagaagtcat cactgtcaaa taattccctg aaaagctcaa aaaattcatc tttgagaact     4620

acttcatcta cagcaacggc tcaaacagtg ccaattgata gctttcataa cttgtcattt     4680

acagaacaaa ttcagcagca ttcattgcca cgcagtagaa gtcgacagtc aattgtttcc     4740

ccatcttcca caacacagtc cttaggacag agtcataatt caccaagtag tgaatttgag     4800

tggagtcaag taaagcccag tttgaagtca actaaagcaa gtaaaggggg gaaatcagaa     4860

aattctgcca agtctggatc agctgggaaa aaagcgaaac aaagtaattc ttcacagcca     4920

aaggttttag aatatgaaat gactcagttt gatagaagag gacctatagc caaatccggg     4980

actgctgcac cacctaaaca aatgccagca gaatctcaat gcaaaattat gataccttca     5040

gctcagcagg aaattggtcg atctcaacag cagtttctta ttcaccaaca aagtggggaa     5100

cagaagaaga gaaatggaat aatgacaaat ccaaattatc atcttcagag caaccaggtt     5160

tttcttggta gggtttcagt cccacgaaca atgcaagata gagggcatca ggaagtgttg     5220

gagggatacc cttcctcaga gacagaatta agccttaaac aagctctgaa gcttcagatt     5280

gaaggttctg accctagctt caactataaa aaggaaacac cattataaaa gtttcctatt     5340

ctgtgaaaca gaagacattg tgatggagtg gttcttcagc tactggatgg aaacatatgc     5400

ctgttgattt gctgaaaaaa caaaaaaaat gaagaatgtg atctctgcag tacagttacc     5460

ttaattactg taatgtgcct aaatagtaag gctgccttct caatgtaacc ctctgtgctt     5520

aaaaaatttc attttgtgtg ctttgtattc actacacagg aataagcact ttttaaaaat     5580

gcagatacat actgcagttc cctgataaaa gctgaaaaga aaatttgagt attttaagtt     5640

aagatgtgat aaaaaatgtg catgtgccat aatcaaatat atatgaaaag gcagtgttcc     5700

ttgtatttat ttttttttct ttttgtggca aaagaaactt aaacatactg tttcagtcac     5760

attgcattgt agtgtatggc ctgtttcttg tatctttaaa gacgttgctc aataaaacaa     5820

atcttgcaac tgttctatgt tcactacacc ttcagcattg gataaaaatc attttctata     5880

taaatatcac attgaaatga aaaaatgatt tcttggcagt ttaaaaaaaa tattttatag     5940

tagtttaggg agctgcttta agtagtttaa atctggattt tcccagtaga attcttctca     6000

tctctggcta aacatgtcag aacaaacaac caaccagtct gtaggcagaa caaagtccta     6060

tttcatccgc tgggatacaa tttcatcttc cattcacttt gtcattccac ctctaagaag     6120

acagactatc attcctgagg catgaaaatt ctcagggaca aagccatgcc tcagtcacat     6180

gtgtgtgcag agagaaatgc acctgtctat ctaagggtag atttttgatc cctgaataat     6240

tcattgacta aactgacctc ttcctcctgg ctaaataaat taattttgct ggcttctctc     6300

tcagcggttt ctattttgta aattgctgca tgaccaaaat agccccactc aaaatcaatt     6360

ggattaattt taatggtttg gttggatgaa tattctggat gaatataaaa tgtgctgccc     6420

ttcacagatg acaccactcc cctgtcaatc atagcacatg tgtacttttt attgttactt     6480

aatagtgatg gatttgcact tttctatcct catactcttt cctgttttct tctttgtaca     6540

attgcatgca ggagggctgg atgccagggt taagagagaa attcatgaca aggaaggtaa     6600

aattggttca aatgagcatg tgtcccacag ccttagtctc cttactctta aatcagtgga     6660

gctgtagctt agatgggtcg tttatatgtc tggaaaagtt gtcataacag tttagaagcc     6720

aaggttgtgg atttgatctt agaatgggcc tgttaatctt atagaaccca gaaattctgt     6780

tcttttcatg tactgttgat gaggaatgag gaaagagaat ttggagattc agcacaaaac     6840

cattgctact tctagaacaa aatctttaga atatgtccta ataacaaagg tcagtaatgt     6900

catcttcata tatgaaggac acatgtgata cattgttcgt ggaaatagaa atgtataatt     6960

atgataaatg tttcacttga atcttattgt aaggcttttc ttgcttttat tttttaaagt     7020

cagcaaaact cattttgtct gtcatctata agtcatagtg aggactacga gataagttga     7080

taagttcaat tgatattaag gtgacatggc aatattaata actcaaatgt gaatgtttca     7140

agtattgaat tcttgtccct atgggacatt tattaaataa aattaatggg actcttgcaa     7200

agtagcctta aaagtgttaa tgagtctatt aataaatatg aacacatact attattagaa     7260

ccaactttac tcatatctca aatacagtac atttacatta ctgtagagga tgaagctcta     7320

atttctatta catgtaattt tctttagaaa gagaaccctg aaagctgcca gtttttctat     7380

taactttgaa ttattgaaat tgtatttatt taattttatt gtttttacaa aattgcacct     7440

tgtgtccaaa gggcgaagat atgacattgc ataagggatt tatgtttttc aaagagctaa     7500

ctgttttcat atccatacta tatacacttg aagcaattgg taggaagaga acctattgga     7560

aaaatacgat tttcaaaagt aagtattcct cgggatgttt ttatataaat tatgttttgg     7620

aatagaacat aaatgacttt gagttaggat aaggatgata ggatgggtgc tggagatgcc     7680

ctgccttgct tatttgtttc tgtgggggat ttaatactat aaatgaaaat ggcttctgct     7740

ccattaaaaa gtaaaaattg tcctccaaat ataaaactcc ttaatagata tttttgaaat     7800

taaaatcttt aaattttata aatcagctgt tgccactaca caactatgat ggcatgtgct     7860

tataacattt ttataacatt ccgtctgtgt ctattcccta aatatcatga gtttataata     7920

aggaaagtga taaaaataca gtaatgaaat aaaaatctga atgtttctaa gaaaggtttt     7980

ggaaggaaaa atgacctgaa atcagtgcgt actgcaaagt acagccaata atttttgttc     8040

tttgttttca cccccaccct cactggaatt ctcaccaaaa atagtttgat acttaaaaaa     8100

cagaagtaaa tacttttctc aatattgttt tggctatgca aatatttgtt ttgcttaatg     8160

tcctccattt acacttctca gcaaatgtag ttgcaaacaa atgctttctt tttatttttc     8220

ccttggtttg aggtatgtaa atagccaaaa atgtacattg aatttcacat tgtaaaagtt     8280

ttattttatc ccttgtatga tattactcaa aaaatccctg tgtatatgaa agtgcataat     8340

aaatatattt gctttacaga gaagatcttg ttttaatttt gtccttgaac cagtagaaca     8400

tgcatgatat gcatatagca taaacaactg ttagttgttt taagttatta tcttaaataa     8460

atcctgagca aatgaatttg gaaacatttt gcaaagaaga aagtgaaata taacactgtc     8520

caaaggaagg tagaaaaaca aagatttact gtttatgtct tcctaagcct ttttaaagac     8580

ttaatgttct tttccccccc gtgactgatt atatactata tcacaccatg tcaggttttg     8640

tgcctctgag aattgcagta atccaataac ttttgtatat gtgtgctcct tgatcatcag     8700

aatattatgg ccatcttatg gcggatattt tgggagttta ttgcaaacat ggtcattcat     8760

tttctaaata aaatttgtgt gtttcttcac tcagtaaaaa aa                        8802


<210>  2190
<211>  12238
<212>  DNA
<213>  homo sapiens

<400>  2190
accccgggca ggtggagcgc tcgcggctgc tcgcggcgag cccgggagtg atggcgaggc       60

ccctgcgggc ggccagcgcc tgaggcgccc cgccccgccc cgccccgcgc ggccctcccc      120

gcccggccct gccctgccct gctccctgcc ggcggctgcg ggcgcttcct agtccgctcg      180

ggcggccgcc caggcgaggt gcggcctccg cacaggcggg gggcgtaggc gcgcggggcc      240

cgccatggct gcgtcggagc tctacacaaa gtttgccagg gtttggatac ctgatccaga      300

ggaagtctgg aagtcagcag agctgctcaa agattataag ccaggagata aagtcctcct      360

gcttcacctc gaggaaggaa aggatttgga ataccatcta gatccaaaga ccaaggagct      420

gcctcactta cgaaatcctg acatacttgt tggtgaaaat gacctcacag ccctcagcta      480

tcttcatgag cctgctgtgc tccataatct cagagtccgc tttattgatt ccaaacttat      540

ttatacgtat tgtggtatag tcctagtagc tataaatccc tatgaacagc tgcctattta      600

tggagaagat attattaatg catacagtgg tcagaacatg ggtgatatgg atccacatat      660

ctttgcagta gctgaagaag cttacaagca aatggccaga gatgaacgaa atcagtccat      720

catcgtaagt ggagagtctg gggcaggaaa aacagtctca gctaagtatg ccatgcgata      780

ctttgcaact gtgagtggtt ctgccagtga ggccaatgtg gaggaaaagg tcttggcctc      840

caaccccatc atggagtcca ttggaaatgc taaaacaacc aggaatgata atagcagccg      900

ttttgggaag tatattgaga ttggttttga taagagatat cgaatcattg gtgccaatat      960

gagaacttat cttttagaga aatccagagt ggtattccag gcagaagagg agagaaacta     1020

tcatatcttc tatcagcttt gtgcctcagc aaagttacct gaatttaaaa tgctacgatt     1080

aggaaatgca gataacttta attacacaaa acaaggaggc agtcctgtga ttgaaggagt     1140

ggatgatgca aaggagatgg cacatactag gcaggcctgc actttgctag gaattagtga     1200

atctcatcaa atgggaattt tccgaatact tgctggcatc cttcacttag gcaatgttgg     1260

atttacatcc cgagatgcag acagctgcac aatacctccc aagcatgaac ctctctgcat     1320

cttctgtgac ctcatgggtg tggactatga ggagatgtgt cactggctct gccatcggaa     1380

actggctact gccacagaga catacatcaa gcccatctcc aagctgcagg ccacgaatgc     1440

ccgcgatgct ttggccaagc acatctatgc caagctcttt aactggattg tagataatgt     1500

caatcaggct ctccattctg ctgtcaaaca gcactctttt attggtgtgc tagacattta     1560

cggatttgaa acatttgaga taaatagttt tgaacagttt tgcataaatt atgcaaatga     1620

aaaactacag caacaattca atatgcatgt cttcaaattg gagcaagaag aatatatgaa     1680

ggaacaaatt ccatggacac tcatagattt ttatgataat cagccttgta ttaatcttat     1740

agaatcaaaa ctaggcattc tagatttact ggatgaggaa tgcaagatgc ctaaaggcac     1800

agatgacacc tgggcccaaa aattgtacaa cacacatttg aacaaatgtg cactctttga     1860

aaagcctcgt ctatcaaaca aagctttcat catccaacat tttgctgaca aagtggaata     1920

ccagtgtgaa ggatttctcg aaaagaataa agacaccgtt tttgaagaac aaattaaagt     1980

tcttaaatca agcaagttta agatgctacc agaactattt caagatgatg agaaggccat     2040

cagtccaact tcagccacct cctcagggcg cacacccctc acacgaactc ctgcaaagcc     2100

caccaaaggc agaccaggcc aaatggccaa agagcacaag aaaacagtgg ggcatcagtt     2160

cagaaactcc ctgcacctgc ttatggagac actcaatgcc actacccctc actatgtgcg     2220

ctgtatcaag cctaatgact tcaagttccc attcacgttt gatgagaaga gggcagtgca     2280

gcagctgaga gcatgtggtg tcctggaaac catccgaatc agtgcggccg gtttcccctc     2340

acggtggact taccaagaat ttttcagccg ctaccgtgtc ctaatgaagc agaaagatgt     2400

gctgagtgac agaaagcaaa catgcaagaa tgtgttagag aaactgatac tggacaagga     2460

caaataccag tttggtaaga caaagatctt tttccgtgcc ggtcaagtgg cctatctaga     2520

aaaattgaga gctgacaaac tgagagctgc ctgcatccgg atccagaaga ccatccgagg     2580

gtggctgctg agaaagaagt acctacgcat gcggaaggca gccatcacca tgcagagata     2640

cgtgcggggc taccaggccc gatgctatgc taagtttctg cgcagaacca aggcagcaac     2700

catcattcaa aagtactggc gcatgtatgt ggtccgcagg aggtacaaga ttagacgagc     2760

tgccactatt gttcttcagt cttacttgcg aggcttcttg gccagaaata ggtatcgcaa     2820

gatactccgt gagcacaaag cagtcatcat tcagaagcga gtccggggct ggctggcccg     2880

cacacactac aagaggagca tgcatgccat catctacctt cagtgctgct tcaggcggat     2940

gatggccaag cgtgagctaa agaagctcaa aatcgaggct cgctcagtgg agcgctataa     3000

gaagctgcac atcggcatgg agaacaagat catgcagctg cagcgcaaag ttgatgagca     3060

gaacaaagac tacaaatgcc ttgtggagaa actaaccaat ctggaaggaa tatacaactc     3120

tgagactgag aaactacgaa gtgacttaga acgtcttcaa ctaagtgaag aggaagcgaa     3180

agttgccact gggcgggtcc ttagtctgca ggaagaaatt gccaagctcc ggaaagacct     3240

ggagcaaact cgttcagaga aaaaatgcat tgaggaacat gcagatcgat acaaacaaga     3300

aacagagcag ctggtatcaa atctgaagga agaaaatact ttgctgaagc aagaaaaaga     3360

agccctcaat caccgcatcg tgcagcaggc taaggagatg acagaaacta tggagaagaa     3420

gttagtagaa gaaacgaaac aactggaact cgaccttaat gatgaaaggc tgagatatca     3480

gaaccttctg aatgagttca gtcgcctgga agaaagatat gatgacctca aggaagagat     3540

gacccttatg gtgcatgtgc ctaagcctgg acacaagaga acagactcca cccacagcag     3600

caacgagtct gaatatatct ttagctctga aattgcagaa atggaagaca ttccatcaag     3660

gacagaggaa ccaagtgaga agaaggtacc tctggacatg tcattgttcc ttaagctcca     3720

gaagcgggtc acagagctgg agcaggagaa gcaggtgatg caggatgagc tggaccgcaa     3780

ggaggagcag gtgctccgca gcaaggccaa ggaagaagaa agaccacaaa ttagaggtgc     3840

agaactggaa tatgagtcac tcaagcgtca agaactagaa tcagaaaaca aaaaactgaa     3900

gaatgagcta aatgagttgc gcaaggccct cagtgagaaa agtgccccag aggtgaccgc     3960

cccaggtgca cctgcctacc gtgtcctcat ggagcagctg acctctgtga gcgaggagct     4020

tgatgtccgc aaggaggaag tcctcatctt aaggtctcaa ctggtgagcc agaaagaggc     4080

catccaaccc aaggatgaca agaatacaat gacagattcc acaatacttt tggaagatgt     4140

acaaaaaatg aaagataaag gtgaaatagc acaagcatac attggtttga aagaaacaaa     4200

tagatcatct gctctggatt accatgagtt gaatgaggat ggagagctgt ggctggttta     4260

tgaagggtta aaacaagcca acaggctcct ggaatcccag ctgcagtcac agaagaggag     4320

ccatgagaat gaggccgagg ccctccgtgg ggagatccag agcctgaagg aggagaacaa     4380

ccgacagcag cagctgctgg cccagaacct gcagctgccc ccagaggccc gcattgaggc     4440

cagcctgcag cacgagatca cccggctgac caacgaaaac ttggatttga tggaacaact     4500

tgaaaaacag gataagacgg tccgtaaact gaaaaaacaa ctgaaagtat ttgccaaaaa     4560

aattggcgaa ctagaagtgg gccagatgga gaacatatcc ccaggacaga tcattgatga     4620

acccatccga ccagtcaaca ttcccaggaa agaaaaggat ttccaaggga tgctggaata     4680

caagaaggag gatgagcaaa aacttgttaa gaacctgatt ctggaactga agccacgtgg     4740

tgtagcagtc aatttgattc caggattacc ggcatatatc ctgttcatgt gtgttcgaca     4800

tgctgactac ctgaatgatg atcagaaagt aaggtcgttg ctaacatcaa caattaacag     4860

catcaaaaaa gtattgaaga aaagaggtga tgattttgaa accgtctcct tctggctctc     4920

taacacatgc cgatttttgc actgcttgaa acagtacagt ggagaagagg gctttatgaa     4980

gcacaacaca tctcgccaga atgaacactg cctcaccaat tttgacctgg ctgagtatcg     5040

gcaggtgctg agtgacttgg ccattcagat ctaccagcag ctcgtgcggg tgttagagaa     5100

catccttcag ccaatgattg tctcaggcat gctggaacat gaaacgattc agggcgtgtc     5160

tggggtgaag cccacagggt tgagaaagcg aacctccagt atcgccgatg agggcaccta     5220

cacactggac tccatcctcc ggcagctcaa ctccttccac tcggtcatgt gtcagcatgg     5280

catggaccct gaactgatca agcaggtggt caagcagatg ttctacatca taggggccat     5340

caccctgaac aaccttctcc tgcggaagga catgtgctcc tggagtaaag gcatgcagat     5400

caggtacaat gtcagtcaac tggaagaatg gctgcgtgac aagaatctga tgaatagtgg     5460

ggctaaagaa accctggaac ctctcattca ggctgctcaa cttttgcaag tgaaaaagaa     5520

aacagatgat gatgcagaag ccatttgttc tatgtgcaat gctttaacta ctgcccagat     5580

tgtgaaagtg ttgaatttgt atactccagt taatgagttt gaagaaagag tctctgtgtc     5640

gttcattcgt actatacaga tgcgtttacg agacaggaaa gactctcccc agctgctcat     5700

ggatgctaaa cacatctttc ctgtcacctt tcctttcaac ccatcttccc tcgcactaga     5760

aaccatccag attccagcca gcctcggcct gggcttcatt tcacgggtct gaaagtgatg     5820

tccaggcaaa aattgacaat acatttcttg cccgaaataa gaacccatta tttccagtga     5880

gttactgaaa atacattttt aaagagaaag tactgattat ctcccaaatg agaagtcatt     5940

aactggaaat ctccctagaa tactttcatc actttggaaa caaagatagg ctctttcgtg     6000

ctgtgttatc tttatagcaa cactcatcct taaccaacta ggtaccgtga gtttacatac     6060

aggagaatga tggaaggaag ggaggaagga aaggaggaga aaaatgtgtc ttcagctggc     6120

agcatttatt ttaaatcctt agcactgagt ttgaatggta taaaaagtat aacttccata     6180

gatgagctgt tgttaggaag gcaccaaaga acctcctctg cactaaacag gagaatggaa     6240

agaaaagtct ccattgagta catatcatgt cagtttagta atcaattatg ttgatattgt     6300

taaactggtt caaagaaata aactggcaat atgtaaagta attcctcatt tgtgtcacta     6360

tgatatagag atattaaagg aatgttggtt tgctaaatag tatagatgtc catttgtact     6420

atagtttact gagcatttta aattgctgct acatactgtc ttcttaaaat gtaagtgata     6480

ttaggcacta caataagttt ctcttgtcaa ttctgtttac aattcaatca gatcacagtt     6540

ttaactggat tatatgcaaa tacctacaga ttcacctgca caagtagcag acactggaaa     6600

gtcatgtagt aatatgacaa aatgcttgac atttaggggt aggattagac aaagtggcta     6660

ttgttgatgt cattatttat tcaggatgta ttacattgat gtgctcatta attttccctg     6720

ggtggatatt gcgtcagggt acagtgttct gtgaagtgac ttatttttaa ctaccagatc     6780

tgattccttc agtgcatatt ttcaaccttg acaggttttc tctcttctta atttattaag     6840

aattaatctc ggctgggcgc ggtggctcac gcctgtaatc ccagcacttt gggaagccaa     6900

ggtgggcgga tcacttcagg ttaggagttg gagaccagcc tggccaacat ggcgaaaccc     6960

tgtctctact aaaaatacaa aaattagccg ggcgtggtgg cacttgcctg taatcccagc     7020

tactcgggag gctgaggcac gagaatcgat taaacctggg aggcggagat tgcaatgaga     7080

tcgaaccact gcactccagc ctgggtgaca gagagagaca ctgccttgga aaaaaaaaga     7140

atctcactca ctatctagag aggattgtca gaatattcac gattcaggtc ttgaaacttt     7200

gattatgcaa aagaaggtat ataataaata tttcattatg attcagtttt taaggctttg     7260

cagcttctat aagtgttctc agatgccact agataatttt aaaagcatca tattagaaat     7320

actttaagaa gacttatata agaaatagaa gattgttgaa ttttacagag gatttggttc     7380

attaagaccc agattctgta agttttcatt ctgaaattct agttaaacat attcaccatt     7440

tttcttagga atcttataca ataaatcctt caggttgcac aaaagcaaat tattagtttt     7500

cattagaaac tctggttctg aattacaatc ataggttata taaatttaac tgttagatgg     7560

tctataaatc ttattaaaat atgtgcaata tttatggaag tcaaacagct tcatatcagt     7620

gataaagatt gttattaaaa gataaatact gtctgttaat ttacatgggc ctcaagttcc     7680

tcgtttataa aataagagag ttggacactg attcttaaca tctcctccac atttaaaatt     7740

ctctcttctc agcccttaga ttctagagag aaaaagctgc agttactcag taagtccatt     7800

ctctgatgga aagaccagtg tgtagtgcct gtcaattcct taggattaat caaatgtaaa     7860

atcacaagtt tgtgtagctg taacctttct taaatgtaca tgatttatgt acatgctttt     7920

agaaggtcct actatatttg tattataatt agtttaagta atttttatta catcatgtat     7980

tgctttattc agtttgaata catttattta tttatttgca gtatcaacca gaaacactac     8040

caattgcatc aaattctccc agtttttcct ggttgtcaat gcggttttca atgcacaatt     8100

aagtcatagc catttggttc gtaccaaatg tgtcagaatc taacagcatc cgataggctg     8160

taagttgggg agttgctaag aaaatgcaac gtggtacagg ctgtccgcct cagccctgga     8220

aatctcccag acctccccca gcttcatcct gtgtagcacg actcaacgtg caccctgaat     8280

cttctcaggt cttccaggtc atgctgtagc tgtcactgcc atgcagccct tttttttact     8340

ccggacagct catgtactga agcgtcatga aagaaaggct gtggtctgag cccttctctc     8400

ccatctcctg tctttgtcct gtcaagtgct ggagccagag ctcctacagc tgcccttggt     8460

ggtttctcct gttcagcgat ggtggcacaa aggttctgct attccagggc tccagcttcc     8520

tcccaggtct acccagagct ccagatgggg gtctgaatta acctctcttg gtggcctgga     8580

gatttttagt cattgacaag aataccttgt aaccagggaa ccccaaggcc cagtaaatga     8640

ttctgtatac cattttcttg aaggtacaag aagattctgc cgactatggg gatctttggg     8700

ccagtttgag gattgctttc cctctgaggt tctttctctc tgtcagccac actttctcac     8760

ccaacttcag acacaccctg ccagcctttc ccctactcat tcactcttcc ccttccctca     8820

acttaatcgt ctatcccgtt gcctgctgtt tgactgtgca ctgaaggcag gtggatggag     8880

tcagtcctca gttgcccctg ctggccttcc tggtgcttac catcagccca atctttgcac     8940

agtccttgtt gttcttactt ctctgcatgc attccttcag aagatcagtc atcaactttt     9000

tcttaattcc tctgtgacac acaatgggaa ttcaaaggaa gagatcttaa aagtcacaac     9060

agttctttat cttaataatc ccctccccat tcaccttact acatgcagac tcacctcaca     9120

cccttacaac ttgaagctga aaatttaaaa gtaatttccc tttttgcagc ttttcctcag     9180

gttaaggctt tgatctgcct gagagtaact ctaaaaggag ggaagataaa tatgggataa     9240

aatccacaaa gtgtagcttc taattccttt ggaagtttaa aaaatttcca catatctgat     9300

gcttcttttg tcaggtgcag aagcacaaaa acatattccg aagccaactg atagggaatt     9360

tggggattat tgtcagtttg gagaatttgc tgtgttattt cttcatttcc atggatagct     9420

catagttggc tctttctggg tgagtaatta tgtgtaatat agatcaaatc ttttactaag     9480

gttacagcta catgttaggg gaggctatga aaatactata ttattataat ttcagtgcag     9540

tgattgttgt gagaaataac tttcatggta accctaggaa aatgggcacc tgccaccatc     9600

ctgagaagtc ctcacacaat gccctttctc tcttacacac acacacacac acatacacac     9660

acacacaccc ccgtcactaa ttcatagagt tccttagcag gcatagtcaa ggatcctctg     9720

ggtaatgtca gctgcttagt gataaaacag agccaaaact agtgcatcct gttgaaagta     9780

atgcagaaac agtacctggg tccagatatg ctttcctgcg gcgctttcct ctgttacctc     9840

gtttcatcct cacagcagca tggacggtag gtggggtcgc ttctacaatc atttctgatg     9900

atagcttggg aatagagata ggggcagtga cttgcctgat gtcgcacagc cctctggctg     9960

tcctgctttc ccatatggag cagtggtggt gtgggcacct gtgatgcagg agactttaaa    10020

aatgtcgtga ggtcacgtgc tgcccctcct ggtacgtgtg gaatgcccct ggccagcaag    10080

gggtgctttt ttatcagagt tggcagctgg catgtgggaa ccgagcaagt gctgcgtacc    10140

aagttacttg ttttaaggag accaagtgct cagcgccagg tggttttctt ttttgtcata    10200

gttacttgct ataactcagc ttgacttctg tcatgaatca gtgctctctg ggaggatgca    10260

atactctgtt tgggcattaa ttggtagcag gttgtctcaa ccaaaaagac aggaaacagc    10320

aaaagcctct ctgaaattaa gaggaaagtt actctcccca cacccatcag agtctttatt    10380

ggagccacca ggtgagctgt gcagcctgga caggcctgca gctataggcc accttcccag    10440

tttaggtcct cagcacaggg gagcccaagt cactgggtgc cttccgaggg ctgtcactgg    10500

gcaggccata tacaagtcag tgtgtgcgtg ggcactgcag tgtgtgcatg ccgtaggtgt    10560

tgatgggtgc taggaggggt gtcgtgtgca tgcgcgttga agaggatctg tattgccgtg    10620

acctctgttc atggatgagt gcattgtaat ttgttctcag gctgtgctgt gagggccgcc    10680

ttaacccttg ctcccttccc ttctagagct gccttaagtt ctccagaact tttcttctgt    10740

aaaggatatc ttgcctggaa gggatatctt gccctgtttc tcaaggtttt gtgagagttt    10800

tgactggatg tggccctgca tgaccctcct tctcctgtac ttcctctttc ctttccaaat    10860

gggaattaga actgtggggc agcaacagtc tcagagccag tgagaggcca gcttagagaa    10920

tgcttctgag ttagtgggac tctgtgtcac aagtaagcaa atgaatatat gaaagaaatt    10980

atggagataa gttagattct tggtaatact taaatgtctt gctttctact aaccttttgt    11040

tactaaaggt aaagggtata actcaaactt tttgtggaca ttcttttcaa aattttttaa    11100

gaaccctgta ctataaaagg ttgagtaaaa acaggaaagc gtgctataag ttcaaatctg    11160

ttgtattacc ctaaattaga taaaccaacc tgaattatag tagatttctc aatagatgag    11220

gaactgaaaa atactatgta aaatatcttc caaaatgctt tttatacttt ttttatttgt    11280

aatttggtct atctaaaatg ttcgttagct taacttaatg ggcgttattg gattcatatg    11340

actaacgttt cctcagtatt gtaatgcttg aaatatttga aagaaaaaat gttgtttttt    11400

agttgaaact ggtatatata attcagtgct tggcaggtta gtatattttt atgcattttt    11460

cagagtcagc agtttcaaat cttattgtta tcatgttata aaattttagc ccacatttca    11520

ggctccgtaa atcatttgag ccattatttt ttcccaacaa atggtgaatt ttttctttaa    11580

atgtggatat atatgttgta atttatgatt cctggttatg tatttttgtg ggatcctgca    11640

gtaaaattga cttttttgtg tctttgggag atttaaattg cgctaacagt gttgcgcaaa    11700

aatgagttca tgccatttaa catattgtat tttaattatt aactgtatta atttactatg    11760

aaatggacat ccttttaact aaaatggaat tgaacattgc agttttcaaa tatttttcct    11820

tgttgggtct ggaaaaggaa ttctactttg atctgcatag aaaattttga tacaattttt    11880

tgaaagttct taggtgaaac atttacccat taaaaaggaa gcagaaatac tgagacatga    11940

aaggcattat caactaactc tagactctag aacccattct agcatatctc acgtgcaatt    12000

tttaaaaata agttaataat tcatctcata tcaacaaaag cctttgaaac atgggttttc    12060

actagatatc acctagtgct aagataaaaa ccaaaacaat atcagaatta catttatgct    12120

ctaaatttgt agttgtccat tgttgtgctt agtaaatgtg tgtcattaat gctgtattct    12180

cctagctatt atggaaactt gtttaaataa agatatggat ataaaaaaaa aaaaaaaa      12238


<210>  2191
<211>  12157
<212>  DNA
<213>  homo sapiens

<400>  2191
accccgggca ggtggagcgc tcgcggctgc tcgcggcgag cccgggagtg atggcgaggc       60

ccctgcgggc ggccagcgcc tgaggcgccc cgccccgccc cgccccgcgc ggccctcccc      120

gcccggccct gccctgccct gctccctgcc ggcggctgcg ggcgcttcct agtccgctcg      180

ggcggccgcc caggcgaggt gcggcctccg cacaggcggg gggcgtaggc gcgcggggcc      240

cgccatggct gcgtcggagc tctacacaaa gtttgccagg gtttggatac ctgatccaga      300

ggaagtctgg aagtcagcag agctgctcaa agattataag ccaggagata aagtcctcct      360

gcttcacctc gaggaaggaa aggatttgga ataccatcta gatccaaaga ccaaggagct      420

gcctcactta cgaaatcctg acatacttgt tggtgaaaat gacctcacag ccctcagcta      480

tcttcatgag cctgctgtgc tccataatct cagagtccgc tttattgatt ccaaacttat      540

ttatacgtat tgtggtatag tcctagtagc tataaatccc tatgaacagc tgcctattta      600

tggagaagat attattaatg catacagtgg tcagaacatg ggtgatatgg atccacatat      660

ctttgcagta gctgaagaag cttacaagca aatggccaga gatgaacgaa atcagtccat      720

catcgtaagt ggagagtctg gggcaggaaa aacagtctca gctaagtatg ccatgcgata      780

ctttgcaact gtgagtggtt ctgccagtga ggccaatgtg gaggaaaagg tcttggcctc      840

caaccccatc atggagtcca ttggaaatgc taaaacaacc aggaatgata atagcagccg      900

ttttgggaag tatattgaga ttggttttga taagagatat cgaatcattg gtgccaatat      960

gagaacttat cttttagaga aatccagagt ggtattccag gcagaagagg agagaaacta     1020

tcatatcttc tatcagcttt gtgcctcagc aaagttacct gaatttaaaa tgctacgatt     1080

aggaaatgca gataacttta attacacaaa acaaggaggc agtcctgtga ttgaaggagt     1140

ggatgatgca aaggagatgg cacatactag gcaggcctgc actttgctag gaattagtga     1200

atctcatcaa atgggaattt tccgaatact tgctggcatc cttcacttag gcaatgttgg     1260

atttacatcc cgagatgcag acagctgcac aatacctccc aagcatgaac ctctctgcat     1320

cttctgtgac ctcatgggtg tggactatga ggagatgtgt cactggctct gccatcggaa     1380

actggctact gccacagaga catacatcaa gcccatctcc aagctgcagg ccacgaatgc     1440

ccgcgatgct ttggccaagc acatctatgc caagctcttt aactggattg tagataatgt     1500

caatcaggct ctccattctg ctgtcaaaca gcactctttt attggtgtgc tagacattta     1560

cggatttgaa acatttgaga taaatagttt tgaacagttt tgcataaatt atgcaaatga     1620

aaaactacag caacaattca atatgcatgt cttcaaattg gagcaagaag aatatatgaa     1680

ggaacaaatt ccatggacac tcatagattt ttatgataat cagccttgta ttaatcttat     1740

agaatcaaaa ctaggcattc tagatttact ggatgaggaa tgcaagatgc ctaaaggcac     1800

agatgacacc tgggcccaaa aattgtacaa cacacatttg aacaaatgtg cactctttga     1860

aaagcctcgt ctatcaaaca aagctttcat catccaacat tttgctgaca aagtggaata     1920

ccagtgtgaa ggatttctcg aaaagaataa agacaccgtt tttgaagaac aaattaaagt     1980

tcttaaatca agcaagttta agatgctacc agaactattt caagatgatg agaaggccat     2040

cagtccaact tcagccacct cctcagggcg cacacccctc acacgaactc ctgcaaagcc     2100

caccaaaggc agaccaggcc aaatggccaa agagcacaag aaaacagtgg ggcatcagtt     2160

cagaaactcc ctgcacctgc ttatggagac actcaatgcc actacccctc actatgtgcg     2220

ctgtatcaag cctaatgact tcaagttccc attcacgttt gatgagaaga gggcagtgca     2280

gcagctgaga gcatgtggtg tcctggaaac catccgaatc agtgcggccg gtttcccctc     2340

acggtggact taccaagaat ttttcagccg ctaccgtgtc ctaatgaagc agaaagatgt     2400

gctgagtgac agaaagcaaa catgcaagaa tgtgttagag aaactgatac tggacaagga     2460

caaataccag tttggtaaga caaagatctt tttccgtgcc ggtcaagtgg cctatctaga     2520

aaaattgaga gctgacaaac tgagagctgc ctgcatccgg atccagaaga ccatccgagg     2580

gtggctgctg agaaagaagt acctacgcat gcggaaggca gccatcacca tgcagagata     2640

cgtgcggggc taccaggccc gatgctatgc taagtttctg cgcagaacca aggcagcaac     2700

catcattcaa aagtactggc gcatgtatgt ggtccgcagg aggtacaaga ttagacgagc     2760

tgccactatt gttcttcagt cttacttgcg aggcttcttg gccagaaata ggtatcgcaa     2820

gatactccgt gagcacaaag cagtcatcat tcagaagcga gtccggggct ggctggcccg     2880

cacacactac aagaggagca tgcatgccat catctacctt cagtgctgct tcaggcggat     2940

gatggccaag cgtgagctaa agaagctcaa aatcgaggct cgctcagtgg agcgctataa     3000

gaagctgcac atcggcatgg agaacaagat catgcagctg cagcgcaaag ttgatgagca     3060

gaacaaagac tacaaatgcc ttgtggagaa actaaccaat ctggaaggaa tatacaactc     3120

tgagactgag aaactacgaa gtgacttaga acgtcttcaa ctaagtgaag aggaagcgaa     3180

agttgccact gggcgggtcc ttagtctgca ggaagaaatt gccaagctcc ggaaagacct     3240

ggagcaaact cgttcagaga aaaaatgcat tgaggaacat gcagatcgat acaaacaaga     3300

aacagagcag ctggtatcaa atctgaagga agaaaatact ttgctgaagc aagaaaaaga     3360

agccctcaat caccgcatcg tgcagcaggc taaggagatg acagaaacta tggagaagaa     3420

gttagtagaa gaaacgaaac aactggaact cgaccttaat gatgaaaggc tgagatatca     3480

gaaccttctg aatgagttca gtcgcctgga agaaagatat gatgacctca aggaagagat     3540

gacccttatg gtgcatgtgc ctaagcctgg acacaagaga acagactcca cccacagcag     3600

caacgagtct gaatatatct ttagctctga aattgcagaa atggaagaca ttccatcaag     3660

gacagaggaa ccaagtgaga agaaggtacc tctggacatg tcattgttcc ttaagctcca     3720

gaagcgggtc acagagctgg agcaggagaa gcaggtgatg caggatgagc tggaccgcaa     3780

ggaggagcag gtgctccgca gcaaggccaa ggaagaagaa agaccacaaa ttagaggtgc     3840

agaactggaa tatgagtcac tcaagcgtca agaactagaa tcagaaaaca aaaaactgaa     3900

gaatgagcta aatgagttgc gcaaggccct cagtgagaaa agtgccccag aggtgaccgc     3960

cccaggtgca cctgcctacc gtgtcctcat ggagcagctg acctctgtga gcgaggagct     4020

tgatgtccgc aaggaggaag tcctcatctt aaggtctcaa ctggtgagcc agaaagaggc     4080

catccaaccc aaggatgaca agaatacaat gacagattcc acaatacttt tggaagatgt     4140

acaaaaaatg aaagataaag gtgaaatagc acaagcatac attggtttga aagaaacaaa     4200

taggctcctg gaatcccagc tgcagtcaca gaagaggagc catgagaatg aggccgaggc     4260

cctccgtggg gagatccaga gcctgaagga ggagaacaac cgacagcagc agctgctggc     4320

ccagaacctg cagctgcccc cagaggcccg cattgaggcc agcctgcagc acgagatcac     4380

ccggctgacc aacgaaaact tggatttgat ggaacaactt gaaaaacagg ataagacggt     4440

ccgtaaactg aaaaaacaac tgaaagtatt tgccaaaaaa attggcgaac tagaagtggg     4500

ccagatggag aacatatccc caggacagat cattgatgaa cccatccgac cagtcaacat     4560

tcccaggaaa gaaaaggatt tccaagggat gctggaatac aagaaggagg atgagcaaaa     4620

acttgttaag aacctgattc tggaactgaa gccacgtggt gtagcagtca atttgattcc     4680

aggattaccg gcatatatcc tgttcatgtg tgttcgacat gctgactacc tgaatgatga     4740

tcagaaagta aggtcgttgc taacatcaac aattaacagc atcaaaaaag tattgaagaa     4800

aagaggtgat gattttgaaa ccgtctcctt ctggctctct aacacatgcc gatttttgca     4860

ctgcttgaaa cagtacagtg gagaagaggg ctttatgaag cacaacacat ctcgccagaa     4920

tgaacactgc ctcaccaatt ttgacctggc tgagtatcgg caggtgctga gtgacttggc     4980

cattcagatc taccagcagc tcgtgcgggt gttagagaac atccttcagc caatgattgt     5040

ctcaggcatg ctggaacatg aaacgattca gggcgtgtct ggggtgaagc ccacagggtt     5100

gagaaagcga acctccagta tcgccgatga gggcacctac acactggact ccatcctccg     5160

gcagctcaac tccttccact cggtcatgtg tcagcatggc atggaccctg aactgatcaa     5220

gcaggtggtc aagcagatgt tctacatcat aggggccatc accctgaaca accttctcct     5280

gcggaaggac atgtgctcct ggagtaaagg catgcagatc aggtacaatg tcagtcaact     5340

ggaagaatgg ctgcgtgaca agaatctgat gaatagtggg gctaaagaaa ccctggaacc     5400

tctcattcag gctgctcaac ttttgcaagt gaaaaagaaa acagatgatg atgcagaagc     5460

catttgttct atgtgcaatg ctttaactac tgcccagatt gtgaaagtgt tgaatttgta     5520

tactccagtt aatgagtttg aagaaagagt ctctgtgtcg ttcattcgta ctatacagat     5580

gcgtttacga gacaggaaag actctcccca gctgctcatg gatgctaaac acatctttcc     5640

tgtcaccttt cctttcaacc catcttccct cgcactagaa accatccaga ttccagccag     5700

cctcggcctg ggcttcattt cacgggtctg aaagtgatgt ccaggcaaaa attgacaata     5760

catttcttgc ccgaaataag aacccattat ttccagtgag ttactgaaaa tacattttta     5820

aagagaaagt actgattatc tcccaaatga gaagtcatta actggaaatc tccctagaat     5880

actttcatca ctttggaaac aaagataggc tctttcgtgc tgtgttatct ttatagcaac     5940

actcatcctt aaccaactag gtaccgtgag tttacataca ggagaatgat ggaaggaagg     6000

gaggaaggaa aggaggagaa aaatgtgtct tcagctggca gcatttattt taaatcctta     6060

gcactgagtt tgaatggtat aaaaagtata acttccatag atgagctgtt gttaggaagg     6120

caccaaagaa cctcctctgc actaaacagg agaatggaaa gaaaagtctc cattgagtac     6180

atatcatgtc agtttagtaa tcaattatgt tgatattgtt aaactggttc aaagaaataa     6240

actggcaata tgtaaagtaa ttcctcattt gtgtcactat gatatagaga tattaaagga     6300

atgttggttt gctaaatagt atagatgtcc atttgtacta tagtttactg agcattttaa     6360

attgctgcta catactgtct tcttaaaatg taagtgatat taggcactac aataagtttc     6420

tcttgtcaat tctgtttaca attcaatcag atcacagttt taactggatt atatgcaaat     6480

acctacagat tcacctgcac aagtagcaga cactggaaag tcatgtagta atatgacaaa     6540

atgcttgaca tttaggggta ggattagaca aagtggctat tgttgatgtc attatttatt     6600

caggatgtat tacattgatg tgctcattaa ttttccctgg gtggatattg cgtcagggta     6660

cagtgttctg tgaagtgact tatttttaac taccagatct gattccttca gtgcatattt     6720

tcaaccttga caggttttct ctcttcttaa tttattaaga attaatctcg gctgggcgcg     6780

gtggctcacg cctgtaatcc cagcactttg ggaagccaag gtgggcggat cacttcaggt     6840

taggagttgg agaccagcct ggccaacatg gcgaaaccct gtctctacta aaaatacaaa     6900

aattagccgg gcgtggtggc acttgcctgt aatcccagct actcgggagg ctgaggcacg     6960

agaatcgatt aaacctggga ggcggagatt gcaatgagat cgaaccactg cactccagcc     7020

tgggtgacag agagagacac tgccttggaa aaaaaaagaa tctcactcac tatctagaga     7080

ggattgtcag aatattcacg attcaggtct tgaaactttg attatgcaaa agaaggtata     7140

taataaatat ttcattatga ttcagttttt aaggctttgc agcttctata agtgttctca     7200

gatgccacta gataatttta aaagcatcat attagaaata ctttaagaag acttatataa     7260

gaaatagaag attgttgaat tttacagagg atttggttca ttaagaccca gattctgtaa     7320

gttttcattc tgaaattcta gttaaacata ttcaccattt ttcttaggaa tcttatacaa     7380

taaatccttc aggttgcaca aaagcaaatt attagttttc attagaaact ctggttctga     7440

attacaatca taggttatat aaatttaact gttagatggt ctataaatct tattaaaata     7500

tgtgcaatat ttatggaagt caaacagctt catatcagtg ataaagattg ttattaaaag     7560

ataaatactg tctgttaatt tacatgggcc tcaagttcct cgtttataaa ataagagagt     7620

tggacactga ttcttaacat ctcctccaca tttaaaattc tctcttctca gcccttagat     7680

tctagagaga aaaagctgca gttactcagt aagtccattc tctgatggaa agaccagtgt     7740

gtagtgcctg tcaattcctt aggattaatc aaatgtaaaa tcacaagttt gtgtagctgt     7800

aacctttctt aaatgtacat gatttatgta catgctttta gaaggtccta ctatatttgt     7860

attataatta gtttaagtaa tttttattac atcatgtatt gctttattca gtttgaatac     7920

atttatttat ttatttgcag tatcaaccag aaacactacc aattgcatca aattctccca     7980

gtttttcctg gttgtcaatg cggttttcaa tgcacaatta agtcatagcc atttggttcg     8040

taccaaatgt gtcagaatct aacagcatcc gataggctgt aagttgggga gttgctaaga     8100

aaatgcaacg tggtacaggc tgtccgcctc agccctggaa atctcccaga cctcccccag     8160

cttcatcctg tgtagcacga ctcaacgtgc accctgaatc ttctcaggtc ttccaggtca     8220

tgctgtagct gtcactgcca tgcagccctt ttttttactc cggacagctc atgtactgaa     8280

gcgtcatgaa agaaaggctg tggtctgagc ccttctctcc catctcctgt ctttgtcctg     8340

tcaagtgctg gagccagagc tcctacagct gcccttggtg gtttctcctg ttcagcgatg     8400

gtggcacaaa ggttctgcta ttccagggct ccagcttcct cccaggtcta cccagagctc     8460

cagatggggg tctgaattaa cctctcttgg tggcctggag atttttagtc attgacaaga     8520

ataccttgta accagggaac cccaaggccc agtaaatgat tctgtatacc attttcttga     8580

aggtacaaga agattctgcc gactatgggg atctttgggc cagtttgagg attgctttcc     8640

ctctgaggtt ctttctctct gtcagccaca ctttctcacc caacttcaga cacaccctgc     8700

cagcctttcc cctactcatt cactcttccc cttccctcaa cttaatcgtc tatcccgttg     8760

cctgctgttt gactgtgcac tgaaggcagg tggatggagt cagtcctcag ttgcccctgc     8820

tggccttcct ggtgcttacc atcagcccaa tctttgcaca gtccttgttg ttcttacttc     8880

tctgcatgca ttccttcaga agatcagtca tcaacttttt cttaattcct ctgtgacaca     8940

caatgggaat tcaaaggaag agatcttaaa agtcacaaca gttctttatc ttaataatcc     9000

cctccccatt caccttacta catgcagact cacctcacac ccttacaact tgaagctgaa     9060

aatttaaaag taatttccct ttttgcagct tttcctcagg ttaaggcttt gatctgcctg     9120

agagtaactc taaaaggagg gaagataaat atgggataaa atccacaaag tgtagcttct     9180

aattcctttg gaagtttaaa aaatttccac atatctgatg cttcttttgt caggtgcaga     9240

agcacaaaaa catattccga agccaactga tagggaattt ggggattatt gtcagtttgg     9300

agaatttgct gtgttatttc ttcatttcca tggatagctc atagttggct ctttctgggt     9360

gagtaattat gtgtaatata gatcaaatct tttactaagg ttacagctac atgttagggg     9420

aggctatgaa aatactatat tattataatt tcagtgcagt gattgttgtg agaaataact     9480

ttcatggtaa ccctaggaaa atgggcacct gccaccatcc tgagaagtcc tcacacaatg     9540

ccctttctct cttacacaca cacacacaca catacacaca cacacacccc cgtcactaat     9600

tcatagagtt ccttagcagg catagtcaag gatcctctgg gtaatgtcag ctgcttagtg     9660

ataaaacaga gccaaaacta gtgcatcctg ttgaaagtaa tgcagaaaca gtacctgggt     9720

ccagatatgc tttcctgcgg cgctttcctc tgttacctcg tttcatcctc acagcagcat     9780

ggacggtagg tggggtcgct tctacaatca tttctgatga tagcttggga atagagatag     9840

gggcagtgac ttgcctgatg tcgcacagcc ctctggctgt cctgctttcc catatggagc     9900

agtggtggtg tgggcacctg tgatgcagga gactttaaaa atgtcgtgag gtcacgtgct     9960

gcccctcctg gtacgtgtgg aatgcccctg gccagcaagg ggtgcttttt tatcagagtt    10020

ggcagctggc atgtgggaac cgagcaagtg ctgcgtacca agttacttgt tttaaggaga    10080

ccaagtgctc agcgccaggt ggttttcttt tttgtcatag ttacttgcta taactcagct    10140

tgacttctgt catgaatcag tgctctctgg gaggatgcaa tactctgttt gggcattaat    10200

tggtagcagg ttgtctcaac caaaaagaca ggaaacagca aaagcctctc tgaaattaag    10260

aggaaagtta ctctccccac acccatcaga gtctttattg gagccaccag gtgagctgtg    10320

cagcctggac aggcctgcag ctataggcca ccttcccagt ttaggtcctc agcacagggg    10380

agcccaagtc actgggtgcc ttccgagggc tgtcactggg caggccatat acaagtcagt    10440

gtgtgcgtgg gcactgcagt gtgtgcatgc cgtaggtgtt gatgggtgct aggaggggtg    10500

tcgtgtgcat gcgcgttgaa gaggatctgt attgccgtga cctctgttca tggatgagtg    10560

cattgtaatt tgttctcagg ctgtgctgtg agggccgcct taacccttgc tcccttccct    10620

tctagagctg ccttaagttc tccagaactt ttcttctgta aaggatatct tgcctggaag    10680

ggatatcttg ccctgtttct caaggttttg tgagagtttt gactggatgt ggccctgcat    10740

gaccctcctt ctcctgtact tcctctttcc tttccaaatg ggaattagaa ctgtggggca    10800

gcaacagtct cagagccagt gagaggccag cttagagaat gcttctgagt tagtgggact    10860

ctgtgtcaca agtaagcaaa tgaatatatg aaagaaatta tggagataag ttagattctt    10920

ggtaatactt aaatgtcttg ctttctacta accttttgtt actaaaggta aagggtataa    10980

ctcaaacttt ttgtggacat tcttttcaaa attttttaag aaccctgtac tataaaaggt    11040

tgagtaaaaa caggaaagcg tgctataagt tcaaatctgt tgtattaccc taaattagat    11100

aaaccaacct gaattatagt agatttctca atagatgagg aactgaaaaa tactatgtaa    11160

aatatcttcc aaaatgcttt ttatactttt tttatttgta atttggtcta tctaaaatgt    11220

tcgttagctt aacttaatgg gcgttattgg attcatatga ctaacgtttc ctcagtattg    11280

taatgcttga aatatttgaa agaaaaaatg ttgtttttta gttgaaactg gtatatataa    11340

ttcagtgctt ggcaggttag tatattttta tgcatttttc agagtcagca gtttcaaatc    11400

ttattgttat catgttataa aattttagcc cacatttcag gctccgtaaa tcatttgagc    11460

cattattttt tcccaacaaa tggtgaattt tttctttaaa tgtggatata tatgttgtaa    11520

tttatgattc ctggttatgt atttttgtgg gatcctgcag taaaattgac ttttttgtgt    11580

ctttgggaga tttaaattgc gctaacagtg ttgcgcaaaa atgagttcat gccatttaac    11640

atattgtatt ttaattatta actgtattaa tttactatga aatggacatc cttttaacta    11700

aaatggaatt gaacattgca gttttcaaat atttttcctt gttgggtctg gaaaaggaat    11760

tctactttga tctgcataga aaattttgat acaatttttt gaaagttctt aggtgaaaca    11820

tttacccatt aaaaaggaag cagaaatact gagacatgaa aggcattatc aactaactct    11880

agactctaga acccattcta gcatatctca cgtgcaattt ttaaaaataa gttaataatt    11940

catctcatat caacaaaagc ctttgaaaca tgggttttca ctagatatca cctagtgcta    12000

agataaaaac caaaacaata tcagaattac atttatgctc taaatttgta gttgtccatt    12060

gttgtgctta gtaaatgtgt gtcattaatg ctgtattctc ctagctatta tggaaacttg    12120

tttaaataaa gatatggata taaaaaaaaa aaaaaaa                             12157


<210>  2192
<211>  4525
<212>  DNA
<213>  homo sapiens

<400>  2192
tttgggaaag tgtggtggtg ggtgcgcgct cgcggcggag ggtaaacatt cgacagtccc       60

cgctctgaga gggagggaca gagagcgaac tgtcagatcg gagcgagagc gggcgcccga      120

gagagggaga gagagagagg gagggagagg aaaagtgaga gagggaaaga gagcgcgaac      180

gagggcgcag agcgagctcc tgctgcaact ctgctccagc acggccagcg ccagcgcccg      240

ccgtcggtgc actctacgag ccgtgcagcg tgcccactgg agttgttgtg tatcaaggat      300

cgatccccta tatgcacaca cacacctcca cctccaccaa tgcactcttc ttcctcctcc      360

ttctccagac aactgctggg aaaaaaataa aacaccaacc ccaaccgtca gcaacaaggt      420

aacagagcga ttcgacatca ttttttttcc tgttcaattt tttccttgtt atatttgttt      480

cctaatttct gcccaaaagg aaagatgtcg catcagactg tgactgttgc gaggagaatg      540

aaaaaggact cttgtttcag aggcaaccaa gagctccggc aatagcaact tcagagaaat      600

gcaccatcgc aagaagtttt cctaggacag aacaaaactt gaaacgagag gaccagaggg      660

ggagagcagg agccagcctc ccctctccgc actcgcgagc agccagcagc accacgcctt      720

caaggacgaa aaagttttac tactctaagg gaaaacgagt gaaatgtgtt cctgaggagg      780

agaggagagg agaggagaga gcggacaaga gaaggagcgg gccggttgct ggtcatccgt      840

aatttggcta aggaagaaag gagcagcttc tttctttgtt atctcccgtg aaaccttcac      900

ttagcaggtg gacggagccc cgcgaccggg cagagtccgg gctcgcccga ggacaggagg      960

aggagcggga gcccgcgcgt cccgggagag cgccccgagt gcaggtcccc gccccgcccg     1020

gcgagccccg ctggagcgag cccagcgcgc cggggctggg gggcggccac gaccccccct     1080

gaagggggtg gccacggagc gcaccccgag aagcgagccc ccctccccag agcgctgctc     1140

ctgcggctgc tgctgctgct ggtgaccaag gccggccggc gacccccgcg ccctgccgag     1200

cggccttgca gctgcagccg ggggccgcgg cggcggcggc ggcggcgggg gcggaggcgg     1260

cggcggagga ggaggcggcg aaggcggcgg ggccggcggg ggcccggggc gggggcgggg     1320

aaggaggggg ggaggaggcg ggaggcgggg ggcgcggcgg cggcggcggc ggcggcggcc     1380

gcggctgctg ctgcggcggc ggcggcggtg gtggcggcgg tggggtggcg ggagcggagc     1440

ggcatggcca cggcggcttc taacccctac ctgccgggga acagcctgct cgcggccggc     1500

tctattgtgc actcggacgc ggcaggggct ggcggcggcg ggggtggcgg cggcggcggc     1560

ggcgggggcg gcgcaggggg cgggggcggc ggcatgcagc cgggcagcgc cgccgtgacc     1620

tcgggcgcct accgggggga cccgtcctct gtcaagatgg tccagagcga cttcatgcag     1680

ggggccatgg ccgccagcaa cggcggccat atgctgagcc acgcgcacca gtgggtcaca     1740

gccctgcccc acgccgccgc cgccgccgcc gctgccgccg ccgccgccgt ggaggcgagc     1800

tcgccgtggt cgggcagcgc cgtgggcatg gctggcagcc cccagcagcc accgcagccg     1860

ccgccgccac cgccgcaggg ccccgacgtg aagggcggcg ccgggcgcga cgacctgcac     1920

gcgggcacag cgctgcacca ccgcgggccg ccgcacctcg gacccccgcc gccgccccca     1980

caccagggcc accctggggg ctggggggcg gccgccgctg ccgcagccgc agccgccgcc     2040

gccgccgccg ccgcgcacct cccgtccatg gccgggggcc agcagccgcc gccgcagagt     2100

ctgctctact cgcagcccgg aggcttcacg gtgaacggca tgctgagcgc gccaccgggg     2160

cccggcggcg gcggcggcgg cgcgggcggt ggagcccaga gcttggtgca cccggggctg     2220

gtgcgcgggg acacgccaga gctggccgag caccaccacc accaccacca ccacgcgcat     2280

cctcacccgc cgcacccgca ccacgcgcag ggacccccgc accacggcgg cggcggcggc     2340

ggcgcggggc ctggactcaa cagccacgac ccgcactcgg acgaggacac gccgacgtcg     2400

gacgacctgg agcagttcgc caagcagttc aagcagcggc gcatcaagct gggcttcacg     2460

caggccgacg tggggttggc gctgggcaca ctctacggca acgtgttctc gcagaccacc     2520

atctgccgct tcgaggccct gcagctgagc ttcaagaaca tgtgcaagct caagccgctg     2580

ctgaacaagt ggctggagga ggcggactca agcaccggca gccccacaag catcgacaag     2640

atcgcggcgc agggccgcaa gcgcaagaag cggacctcta tcgaggtgag cgtcaagggc     2700

gcgctggaga gccacttcct caagtgcccc aagccctccg cgcaggagat caccaacctg     2760

gccgacagcc tgcagctcga gaaggaggtg gtgcgggtct ggttctgcaa tcggcgccaa     2820

aaggagaagc gcatgacgcc gcccgggatc caacagcaga cgcccgacga cgtctactcg     2880

caggtgggca ccgtgagcgc cgacacgccg ccgcctcacc acgggctgca gacgagcgtt     2940

cagtgaagcc agggcgcaga gcgaagaggg ccgccgccgc cgccgcctcc gcagccgccg     3000

tcagcaccgc cgccgcccct gccgccgccg ccgccgccgc cgccgccgct gccgccgccg     3060

cgccgaccct gcacctgggc cgctccgggc tccagcccag gcccatccgc cgccctcccc     3120

tccacccaga gacaggcatg cccgcccttg gaggagaaaa cgcgggagaa acggaccaag     3180

gaggcatttt tgcagtccaa ggaaggaggg gccaaaaaat aaaaagcata ataaacaccc     3240

agactgtttt gtatacatat ataacaaaca aaaccggaag agaaaaaggg ggcgatcatg     3300

agatctcgtt catactgtgg tggtgtttcg tttttgtttt tgtttttaaa gaagggtgaa     3360

gatgcctgac gcacgaaaac tgcactcgtg aggtttttcc accctgagat gacctacacg     3420

gcagcggtgg acagcacctg cctcgtcttc tcctctttga aaaaaagaga gagagagagt     3480

cccctttcct ttcactttct ccctccaaaa cagctgccta aagagatcca cggaaacttt     3540

atttcctggg agcgacctga gagaaaacag aggcaccagg ttccatcagg ggacgacacc     3600

gtgctctggg accctgtttt tcttggccat attaaagtca tttggaaaca aatcaactct     3660

gaaatgggaa ggagggggga aaaacagtct ccaagaaaaa aataattata ttgacagctt     3720

ctgaaactaa cagactgaat agcaaagcca aaagaaaagt atcctcaaag taaccttgga     3780

aataaaagga tcgggaagga gcagagggag agggggaacg tccgctgagg agtggcgaga     3840

ggccccggcc gagtcgggtc gcgggcgggc gggcgaactg ggagcagagc gggggcccag     3900

ccagcgaggc cgccgagcca ggcccggccg cgtacccagg ctttgacggc tgccattcag     3960

ggtggacgat gcctaaagat tccaccgcta atattttttt tattaatatt ttttattttt     4020

tatttctgga ctgactcaga taaaggaatt tagaaagact gagcaccagc cgctgcactt     4080

ctctggactt ctctcctcaa tccgttgcca actttgattg aatgggtgct gtggatgtga     4140

ttatataata ctgccatttc caagcagtgt ttttggtagg ttttaataaa cagacttttc     4200

aaaagacggc aatatagaat tgttagatcc gttgttgatc taaaaatatt tgctttatat     4260

tttcattaaa tgacttcttt taatatttta ttcagaatac ttatgaactg ctgcaaaacg     4320

gtaatttatt tttccccaga tcttgtatta cgtgtttttt tcagacgagc acaaatcaaa     4380

atgaaatgaa aatatggaca gttgttaggt aataagggta tcttttgatg tgatcatttg     4440

attgtaattt aatttgagta gtgattccgt aagagctgat cgagaaaata aatttgttag     4500

aatgaaaaaa aaaaaaaaaa aaaaa                                           4525


<210>  2193
<211>  4946
<212>  DNA
<213>  homo sapiens

<400>  2193
cgggatgggg gagctccagg gcacggcgtc agcggattca cggagaagga gaaaagcccc       60

actgccgtgc agaagcctag gcccgggtga gacgcctgcg aaggctgcca gcagcggaag      120

agaaggggcg tcctccgtgc tgcgcagcac tcgcccgcgg taggtgggcg cggagctcag      180

agctgggagc caaacgcaaa cgctggcgag aagccccagc cccctccggc agcccactcg      240

ctgcggggag gggtttctca cgcccccagc tcctgggaga ctgcaccgga ggtcggaagt      300

aagccgggcg aggatgaatc atcccgccta actcctcctt cccggtcccc tagcctccgc      360

acgccggccc ccttcagaga tcttgcagcc gcgagcgaag actgccctat cctcagactc      420

taccgaaccc cctgtggcct gcggagacga ggagacggac gggtctggtg gccaatgaga      480

gcttcgatct cttgcccccc gcccaatggg ccgctgctca tgggccgggg cgggactagg      540

agggcaggta ggggcggtcc gggctggcgc gcggcgcggc ggctacgcgg ctgcggctca      600

cagagctagc gcctctctgg gtgtccgtgc cagtgctgcg cgggaaggca ccaccaccac      660

agccgccgcc gctggccagg gtgctggaca agacgggccc gtcggccacc tcgccagctc      720

aggcacccgc tgcagccgtc gctgtctcct cccagaccgg tccccatgga ggagatggaa      780

gaggagttga aatgccccgt gtgcggctcc ttctatcggg agcccatcat cctgccctgc      840

tctcacaatt tgtgtcaggc gtgcgcccgc aacatcctgg tgcagacccc agagtctgaa      900

tccccccaga gccatcgggc cgcgggctcc ggggtctccg actatgacta tctggacctg      960

gacaagatga gcctatacag cgaggcggac agcggctatg gctcctacgg ggggttcgcc     1020

agcgccccca ctaccccgtg ccagaagtcc cccaacggcg tccgcgtgtt tcccccggct     1080

atgccgccac cggccaccca cttgtcaccg gccctggccc cggtgccccg caactcctgt     1140

atcacctgcc cccagtgtca ccgcagcctc atcctggatg accgggggct ccgcggcttc     1200

cccaagaatc gcgtactgga aggggtaatt gaccgctacc agcagagcaa agccgcggcc     1260

ctcaagtgcc agctctgcga gaaggcgccc aaggaagcca ccgtcatgtg cgaacagtgc     1320

gatgtcttct actgcgatcc gtgccgcctg cgctgccacc cgccccgggg gcccctagcc     1380

aagcaccgcc tggtgccccc ggcccagggt cgtgtgagcc ggaggctgag cccacgcaag     1440

gtctccacct gcacagacca cgagctggag aaccacagca tgtactgcgt gcaatgcaag     1500

atgcccgtgt gctaccagtg cttggaggag ggcaaacact ccagccacga agtcaaggct     1560

ctgggggcca tgtggaaact acataagagc cagctctccc aggcgctgaa cggactgtca     1620

gacagggcca aagaagccaa ggagtttctg gtacagctgc gcaacatggt ccagcagatc     1680

caggagaaca gtgtggagtt tgaagcctgt ctggtggccc aatgtgatgc cctcatcgat     1740

gccctcaaca gaagaaaagc ccagctgctg gcccgcgtca acaaggagca tgagcacaag     1800

ctgaaggtgg ttcgagatca gatctctcac tgcacagtga aattgcgcca gaccacaggt     1860

ctcatggagt actgcttgga ggtgattaag gaaaatgatc ctagtggttt tttgcagatt     1920

tctgacgccc tcataagaag agtgcacctg actgaggatc agtggggtaa aggcacactc     1980

actccaagga tgaccacgga ctttgacttg agtctggaca acagccctct gctgcaatcc     2040

atccaccagc tggatttcgt gcaagtgaaa gcttcctctc cagtcccagc aacccctatc     2100

ctacagctgg aggaatgttg tacccacaac aacagcgcta cgttgtcctg gaaacagcca     2160

cctctgtcca cggtgcccgc cgatggatac attctggagc tggatgatgg caacggtggt     2220

caattccggg aggtgtatgt ggggaaggag acaatgtgca ctgtggatgg tcttcacttc     2280

aacagcacat acaacgctcg ggtcaaggcc ttcaacaaaa caggagtcag cccgtacagc     2340

aagaccctgg tcctccaaac gtctgaggtg gcctggtttg ctttcgaccc tggctcggcg     2400

cactcggaca tcatcctctc caatgacaac ctgacagtga cctgtagtag ctatgatgac     2460

cgggtggtgc tagggaagac tggcttctcc aagggcatcc actactggga gctcacggta     2520

gatcgctatg acaaccaccc tgatcctgcc tttggtgtgg ctcgcatgga cgtgatgaag     2580

gatgtgatgt taggaaaaga cgacaaagct tgggcaatgt atgtggacaa taaccggagc     2640

tggttcatgc acaacaactc gcacaccaac agaactgagg gagggatcac aaaaggggcc     2700

acaattgggg tcctcctcga cttaaataga aaaaacttga cattttttat caacgatgaa     2760

caacaaggtc ccatagcatt tgataacgtg gagggcctct tcttccctgc ggtcagcctg     2820

aacaggaacg tgcaggtcac gctgcacacc gggctcccag tccccgactt ctactccagc     2880

agagcatcaa tagcctaagg atgtgccgtg gaggcgccag ctgcctgttc ttacctccgc     2940

ctgcgagagc cacagcaagg agctcagcca gccgtggtgg ggtgcagagt tggcaggagt     3000

gggagaagga ggagagaaaa gctggtcctc tgcagtcttt acacccacag ctctgccctt     3060

ttccctttca acctctcctc cgctgtcatg cctgcttccg cttccatgtc caacaattct     3120

aaccaacaaa ggacctagac agcccaccaa gtcacttggt tcccactccc agattttgct     3180

tttatttaac ttaatttttt atgtaggtga gttatatttt ctttcttttc tgatcaggtt     3240

attggtgact tactggactg gcaccgccag gagaaaattc tcctgctaac tttttttctt     3300

aagctttctg tcaaacaatg aggttgtagg gggaggtagg gaagaatgag ctgaatttgt     3360

agcatacagc ttacctgcta gaatgttctt accctcttac ctctcctgta gcgttagctc     3420

tgcagagcta agctttggga gaatgaatct atcactgaga agttttacta ctcattgaag     3480

cacaaaaata tccgctacac aggttcacat cagggtagga tcgttaggat ggctctataa     3540

ttaggatagg ccagaaccct ggccactgta taaaattgga aagtctctaa gacacaggca     3600

aaccagggga cttaatgatt tggttcgttt atttaataaa agcttttaat tgagaaccta     3660

ctattgacca ggcactgttc aagacactag aacattatgt tctagacact gtggggacac     3720

agtggtgaac agacaggcat ggtctctgcc cttcggagct tatattccag taggagaaaa     3780

agcaaaaata aaataattat aaatggtcat atgtactaga aaggaaatgg gcaagggtca     3840

aagagactca tgggcaagat ctttcaggct tcctagaatg atgctaaaaa tccacacatt     3900

ctggccatag caccagaaat gtaccaactc aatgcctttt cagctgcact atttaattat     3960

ggtacctgct gccactcatc acagagccct tcttggtaga aatgatgtca gcattcttat     4020

ttgctgatgc tgctatgata ccacgcctta aaaattgaca gttgaaaaaa aaaagagtga     4080

ccagagggca aaggacccat tctcagtaat gggagatctt gagttgcagt ccacagcatt     4140

cacattctca ggataaacat gcttgtctcc atatatacta tctgtgcctg ttatgaatga     4200

aaaatccatc cactctgctg ccattcacag cctaattttc tggagtagtc caaacaatgt     4260

ttggaaaaac atgggactgt atgtcattac tatgactgat agcagaataa taatgcatct     4320

tacttctata tagagataga cttacatagg ttacccttga aattcattag tttgtcataa     4380

agttttagga aaggtaggac ccggaaagaa gttctaatta gttgtctaaa tatttttcag     4440

tgagccaaga aattcaccat gaaaaaacaa gaataacaaa tagaagggaa gagataggat     4500

gggaaagcta acaaattaaa gttttggcaa aaaggaatat atgtaaatag ctaattattt     4560

acttttgtgc ttactttatt tagattattt ctatcagtta caatcttttt ctagttaagt     4620

gtacctaatt tatggaatgg gtgctatcct gtttatgtgt gtcttggttt ttcttggcta     4680

cagaaaaact gttgcagggc aacactagtt tgatatttga tttactctcc aatgagactc     4740

aatggctggg ccgtggtaga ctcatagttc ctcttgttct ttattaaatt catcctgcta     4800

attagatttc tagtgacttg taacatgtag tttacactga attgcaatta cagatgcata     4860

caactactat actagaaaaa attgtcattt ctgatgtgcc aataaatgat ttttatgaga     4920

gaataaaaaa aaaaaaaaaa aaaaaa                                          4946


<210>  2194
<211>  4393
<212>  DNA
<213>  homo sapiens

<400>  2194
cgggatgggg gagctccagg gcacggcgtc agcggattca cggagaagga gaaaagcccc       60

actgccgtgc agaagcctag gcccgggtga gacgcctgcg aaggctgcca gcagcggaag      120

agaaggggcg tcctccgtgc tgcgcagcac tcgcccgcgg taggtgggcg cggagctcag      180

agctgggagc caaacgcaaa cgctggcgag aagccccagc cccctccggc agcccactcg      240

ctgcggggag gggtttctca cgcccccagc tcctgggaga ctgcaccgga ggtcggaagt      300

aagccgggcg aggatgaatc atcccgccta actcctcctt cccggtcccc tagcctccgc      360

acgccggccc ccttcagaga tcttgcagcc gcgagcgaag actgccctat cctcagactc      420

taccgaaccc cctgtggcct gcggagacga ggagacggac gggtctggtg gccaatgaga      480

gcttcgatct cttgcccccc gcccaatggg ccgctgctca tgggccgggg cgggactagg      540

agggcaggta ggggcggtcc gggctggcgc gcggcgcggc ggctacgcgg ctgcggctca      600

cagagctagc gcctctctgg gtgtccgtgc cagtgctgcg cgggaaggca ccaccaccac      660

agccgccgcc gctggccagg gtgctggaca agacgggccc gtcggccacc tcgccagctc      720

aggcacccgc tgcagccgtc gctgtctcct cccagaccgg tccccatgga ggagatggaa      780

gaggagttga aatgccccgt gtgcggctcc ttctatcggg agcccatcat cctgccctgc      840

tctcacaatt tgtgtcaggc gtgcgcccgc aacatcctgg tgcagacccc agagtctgaa      900

tccccccaga gccatcgggc cgcgggctcc ggggtctccg actatgacta tctggacctg      960

gacaagatga gcctatacag cgaggcggac agcggctatg gctcctacgg ggggttcgcc     1020

agcgccccca ctaccccgtg ccagaagtcc cccaacggcg tccgcgtgtt tcccccggct     1080

atgccgccac cggccaccca cttgtcaccg gccctggccc cggtgccccg caactcctgt     1140

atcacctgcc cccagtgtca ccgcagcctc atcctggatg accgggggct ccgcggcttc     1200

cccaagaatc gcgtactgga aggggtaatt gaccgctacc agcagagcaa agccgcggcc     1260

ctcaagtgcc agctctgcga gaaggcgccc aaggaagcca ccgtcatgtg cgaacagtgc     1320

gatgtcttct actgcgatcc gtgccgcctg cgctgccacc cgccccgggg gcccctagcc     1380

aagcaccgcc tggtgccccc ggcccagggt cgtgtgagcc ggaggctgag cccacgcaag     1440

gtctccacct gcacagacca cgagctggag aaccacagca tgtactgcgt gcaatgcaag     1500

atgcccgtgt gctaccagtg cttggaggag ggcaaacact ccagccacga agtcaaggct     1560

ctgggggcca tgtggaaact acataagagc cagctctccc aggcgctgaa cggactgtca     1620

gacagggcca aagaagccaa ggagtttctg gtacagctgc gcaacatggt ccagcagatc     1680

caggagaaca gtgtggagtt tgaagcctgt ctggtggccc aatgtgatgc cctcatcgat     1740

gccctcaaca gaagaaaagc ccagctgctg gcccgcgtca acaaggagca tgagcacaag     1800

ctgaaggtgg ttcgagatca gatctctcac tgcacagtga aattgcgcca gaccacaggt     1860

ctcatggagt actgcttgga ggtgattaag gaaaatgatc ctagtggttt tttgcagatt     1920

tctgacgccc tcataagaag agtgcacctg actgaggatc agtggggtaa aggcacactc     1980

actccaagga tgaccacgga ctttgacttg agtctggaca acagccctct gctgcaatcc     2040

atccaccagc tggatttcgt gcaagtgaaa gcttcctctc cagtcccagc aacccctatc     2100

ctacagctgg aggaatgttg tacccacaac aacagcgcta cgttgtcctg gaaacagcca     2160

cctctgtcca cggtgcccgc cgatggatac attctggagc tggatgatgg caacggtggt     2220

caattccggg aggtgtatgt ggggaaggag acaatgtgca ctgtggatgg tcttcacttc     2280

aacagcacat acaacgctcg ggtcaaggcc ttcaacaaaa caggagtcag cccgtacagc     2340

aagaccctgg tcctccaaac gtctgagggt aaggcccttc agcagtatcc ctcagagcga     2400

gaactgcgtg gcatctaaag tggctggcaa gcccggaggt aaccccacca ctgcccacat     2460

tcctgaagtg tttccatgac ttgctctgca ttctgcacag agccgctgtt cctctcctgc     2520

ctttagagag cctatggtat gtggatgtga tcaaaccaaa gattccacat cggcagttcc     2580

aatggcttgg gccggcggct tcctttgata acaatctaaa taagctgcag ttgaagaagc     2640

tgaaaaatga aggcctgaat gtgcccctgg tgtgtaagac aaatgtatct aggctctaga     2700

gcaggctccc attctccacc gatacacatc atgtgccagt tttgcccaga tgattctaaa     2760

ttactctgta gtacttgctt gttctgaggg tgggacctag gttctttcca gtcgtggatt     2820

tgtatgactg aatgtgtttc aaatgggtgg tggggtgcta gagctgttta gagagggcct     2880

gttggctgct cctggcttac ccacttagac tgcctccgtt tcatacccaa agcggaggcc     2940

gtcagcacca ggattgagac ttcctgtggg caccaaacag gaagagacca gcaacttcgc     3000

attacccgcc attttcatct ttgccagtcc cttcagtctt ggctaggcta ccgagagcca     3060

ccatacaagg ttcatctcta gagaattttt gcttcttagc tatactttaa atattttggt     3120

catcaaagac aagtaatgtg tctcagatga gaggcttgaa tttgatggcc agatataacc     3180

tctgaggctt ttaacatttt cattttaaga gtaagcaaga cacatgaaat taaacctaca     3240

aggaggtatt tgtggctggt gccaaagcat tctgacactt tggggtgtca ttttaatcaa     3300

agaaatcacc cccccacctc accgggattc tccataactt ccctctgcag aactaattat     3360

gttgattttg ttcaagttca agatgttagc taaaagaact atggtggtgt tttttttccc     3420

acttcccaca aacctcaaca tgtgccagtc accctaaaat gcttcacatg gttaaaaaca     3480

agcacaattt tgaatcctac agcaaggatg aaaggcccct agccgtgaaa acagtgcttt     3540

ggggagcagt tgtcagtcta agtgatgcta ttccaagaga aggatatgct gagggaaaat     3600

gcccacatga cctgttccca tttggagtac agtgatgtgg tagctacagc ttcccccaga     3660

attatcattt tagcaccttc tctcagggat gacctatcag tttgagagca gttgcctctt     3720

ttctcaaaat accatactaa ctgctaaagc cctccaagag tctttcctag atgcaacgca     3780

gaaggccctt gctggtgatg gcctcatttc ccatgtgtgt acaaggtggt ttgattgaag     3840

agtgaagtgc atgcctgcag agcagagaga aatttgtagc aatgttgcta atatgtgtta     3900

tcagatctgc gggaaaacta tttctattca taatacatca tgggaatcat actattctgg     3960

taaaaatcag ttattagcat aacagcctga gcacttatgt ctctcgtttc atcctgcagg     4020

aggatgtagc gcctcagttt attttaatgt tcataagatt atggtgtcta atttaataaa     4080

ttacaggatt ggaactgcga tccttggtac cacagtcaca gaactggggg tcattttcta     4140

gatgaaacaa acggaacaag ttctcttcca acaaagaaac tgtactgtag aaattaattt     4200

cctccatgaa ttttatatat tgtgtacaaa tataaggtat gtatctgaat acaaagaaaa     4260

gcctatcatc atatagatat cagtattctc tgttactgca cagaagtaat tttctcatga     4320

tgaaataaag ttcacacaca tactttctcc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     4380

aaaaaaaaaa aaa                                                        4393


<210>  2195
<211>  3982
<212>  DNA
<213>  homo sapiens

<400>  2195
ggggatgcgg ctgtgggcgc cggggccggg tagctgctcc aggcgcgcga gctaaccgag       60

tgcggcgagg gcctaccagg ggcgacaggg tttctctccg caagcgcgcg atgcagcggg      120

cggcggcgct ggtccggcgg ggctgtggtc cccggacccc cagctcctgg ggccgcagcc      180

agagcagcgc ggccgccgag gcctcggcgg tgctcaaggt gcggcccgag cgcagccggc      240

gcgagcgcat cctcacgctg gagtccatga acccgcaggt gaaggcggtg gagtacgccg      300

tgcggggacc catcgtgctc aaggccggcg agatcgagct cgagctgcag cggggtatca      360

aaaagccatt cacagaggtc atccgagcca acatcgggga cgcccaggct atggggcagc      420

agccaatcac cttcctccgg caggtgatgg cactatgcac ctacccaaac ctgctggaca      480

gccccagctt cccagaagat gctaagaaac gtgcccggcg gatcctgcag gcttgtggcg      540

ggaacagcct ggggtcctac agtgctagcc agggtgtcaa ctgcatccgt gaagatgtgg      600

ctgcctacat caccaggagg gatggcggtg tgcctgcgga ccccgacaac atctacctga      660

ccacgggagc tagtgacggc atttctacga tcctgaagat cctcgtctcc gggggcggca      720

agtcacggac aggtgtgatg atccccatcc cacaatatcc cctctattca gctgtcatct      780

ctgagctcga cgccatccag gtgaattact acctggacga ggagaactgc tgggcgctga      840

atgtgaatga gctccggcgg gcggtgcagg aggccaaaga ccactgtgat cctaaggtgc      900

tctgcataat caaccctggg aaccccacag gccaggtaca aagcagaaag tgcatagaag      960

atgtgatcca ctttgcctgg gaagagaagc tctttctcct ggctgatgag gtgtaccagg     1020

acaacgtgta ctctccagat tgcagattcc actccttcaa gaaggtgctg tacgagatgg     1080

ggcccgagta ctccagcaac gtggagctcg cctccttcca ctccacctcc aagggctaca     1140

tgggcgagtg tggttacaga ggaggctaca tggaggtgat caacctgcac cctgagatca     1200

agggccagct ggtgaagctg ctgtcggtgc gcctgtgccc cccagtgtct gggcaggccg     1260

ccatggacat tgtcgtgaac cccccggtgg caggagagga gtcctttgag caattcagcc     1320

gagagaagga gtcggtcctg ggtaatctgg ccaaaaaagc aaagctgacg gaagacctgt     1380

ttaaccaagt cccaggaatt cactgcaacc ccttgcaggg ggccatgtac gccttccctc     1440

ggatcttcat tcctgccaaa gctgtggagg ctgctcaggc ccatcaaatg gctccagaca     1500

tgttctactg catgaagctc ctggaggaga ctggcatctg tgtcgtgccc ggcagtggct     1560

ttgggcagag ggaaggcact taccacttca ggatgactat cctccctcca gtggagaagc     1620

tgaaaacggt gctgcagaag gtgaaagact tccacatcaa cttcctggag aagtacgcgt     1680

gaggacgcct gagccccagc gggagacctg tccttggctc ttcctcccaa tgcccgtcag     1740

gctgaactcg cctcccccgt gactctgcct cgggcctcgc agaggccgct ggtcacttcg     1800

tcatcatttt gcccctggag acgtctttct ttgtgccttg atgttgagag cgcctctctt     1860

ttgagcaaac aagcattcta tatgcaacca gagtagaggg gacctgctca gcaggtgtga     1920

ccagggttct ctgaatctgt tattgttttt gcttctggaa agttcatttg gggtttacaa     1980

caactaggat gtgttgggtg agatgtttca gatctggaga aatgagcagg tgtcgggaaa     2040

tgtgtgactt aaccgtggtg agggctggaa atccaaactc accaccatga tctgtgaaat     2100

aaagccctta gcggtgtgaa gcatccggtc ctttgaacag aagggcctgg aaggcccctg     2160

gggctgagaa agggtccgcc cggtggcctg gaggcaggcg ccgggagcgc agtagcacgt     2220

ggactgggca ggatgttgca ctagcttggg gtagatgctg ggggctgcgg ccacggtcag     2280

agggccccac tgtgaggcgt gggtgtgagc caggctgcag gaggaactgg gcctccgctt     2340

cccagcaacg cagccaggcc tgagaattct gtgcgcccgg cgggctttgg gaatgagggg     2400

ttcccttgaa catgcgtagg ctggaacccc gtctgagagg tctccctgaa tttcagtgac     2460

acatagtgca gcccggcagt gtcccacttc cgtggagaga gccgctggaa tggtgtggac     2520

ccatcccgcg ggtgaccggt gcctgttctc ccctgaccga gcctgtgagc acatcgcccc     2580

ctgctggcga cagcggggaa atgagggctg aaaatatcct ccccacaagg gcaatccccg     2640

ggacctgccg agcagccaag gccctgtcct ttcttgaatg gtggcgagct gaatctggtc     2700

ggtttcctag cttttaggtg gtaaaagtgc ctggcagctt ggctgccgtg gaggagtcag     2760

tcgtggttgg aggttcattg ccgtgctttc atgcagagtg ttttgccttc atgttagctt     2820

ccggctcccc tcccaggctg cagactctga cctgtggcat caggcttctc ccagtacagg     2880

agggtgccat cccccagcat gcggcttctc tgccattagc agccctgggc gggccgacca     2940

cactcgaggc tgcggtgcta cgggcttagc cctcgcctcc ctcactggga gcttccccat     3000

cctccctgcc ttccccagtg ggaagttagg gaagctcagg agcctgggac cccgcatgtc     3060

ccaaaatggg attggagaag ctggagagaa agcagaagag gccgaggagt gaggcagcag     3120

cctctatgct gtgatttcca caccgggtcc gtgcagagga aacagaaact cccaactgtc     3180

cttacccacc gacatcacag cccctatgaa gaaagtagcc acaatctcaa ataacaaaag     3240

ggaatgttct aaaacttttt cttccttaaa aaatggagaa aattgcactt gtgcttgctg     3300

tgtggtatat aaaccaggat tagtcccagg gtcgtgaggt ttctggtgaa aaggttaaat     3360

cgtagaagct agtatatttt ttatattttt gtaacaattg cttttttcat gggggaggcg     3420

gggttagtat ttatagtcct aacaagtcca gtaatttttt ataaatcttc agattataaa     3480

cagcccctaa aaactttaca acgtttacac agttttttaa aaagagactg tatacacttg     3540

atttgctttc aaaataaata aggtcagcta gtctaggagg ttaacgtcgg gtaggaatgc     3600

tgatcatgat aggtttggtt ttctacagat tctgttccgg tgcctttcct atccaggcac     3660

cacctgagaa agttgtcatt tgaggtcgca cttggaagtt acatctgtga agtttctgtc     3720

attcgtccag atctgtgtgt gtagcatgtg ctgaggaagc acgtgctggg ctgtgcctca     3780

gacagtgcat caccgggcac ccagaggctt gcctggctat tcctgttctg gtgtgtgtgg     3840

agtgttgggg aggaacagat gcagatcaac ctgtggctgt tttcccgtct aggttctcac     3900

aggtatctcc tgacagaggt acttaacaat ggctctgctg gaaatttcta taaataaaat     3960

gtccaaaatg gtgactgcgt tt                                              3982


<210>  2196
<211>  3806
<212>  DNA
<213>  homo sapiens

<400>  2196
aaactaagcc ggtttcaagt ttcagctcct ccttgaattc caggctgctg agacttccct       60

ctagaatcct ccaacatgga gcctcttgca gcttacccgc taaaatgttc cgggcccaga      120

gcaaaggtat ttgcagtttt gctgtctata gttctatgca cagtaacgct atttcttcta      180

caactaaaat tcctcaaacc taaaatcaac agcttttatg cctttgaagt gaaggatgca      240

aaaggaagaa ctgtttctct ggaaaagtat aaaggcaaag tttcactagt tgtaaacgtg      300

gccagtgact gccaactcac agacagaaat tacttagggc tgaaggaact gcacaaagag      360

tttggaccat cccacttcag cgtgttggct tttccctgca atcagtttgg agaatcggag      420

ccccgcccaa gcaaggaagt agaatctttt gcaagaaaaa actacggagt aactttcccc      480

atcttccaca agattaagat tctaggatct gaaggagaac ctgcatttag atttcttgtt      540

gattcttcaa agaaggaacc aaggtggaat ttttggaagt atcttgtcaa ccctgagggt      600

caagttgtga agttctggaa gccagaggag cccattgaag tcatcaggcc tgacatagca      660

gctctggtta gacaagtgat cataaaaaag aaagaggatc tatgagaatg ccattgcgtt      720

tctaatagaa cagagaaatg tctccatgag ggtttggtct cattttaaac attttttttt      780

tggagacagt gtctcactct gtcacccagg ctggagtgca gtagtgcgtt ctcagctcat      840

tgcaacctct gcctttttaa acatgctatt aaatgtggca atgaaggatt tttttttaat      900

gttatcttgc tattaagtgg taatgaatgt tcccaggatg aggatgttac ccaaagcaaa      960

aatcaagagt agccaaagaa tcaacatgaa atatattaac tacttcctct gaccatacta     1020

aagaattcag aatacacagt gaccaatgtg cctcaatatc ttattgttca acttgacatt     1080

ttctaggact gtacttgatg aaaatgccaa cacactagac cactctttgg attcaagagc     1140

actgtgtatg actgaaattt ctggaataac tgtaaatggt tatgttaatg gaataaaaca     1200

caaatgttga aaaatgtaaa atatatatac atagattcaa atccttatat atgtatgctt     1260

gttttgtgta caggattttg ttttttcttt ttaagtacag gttcctagtg ttttactata     1320

actgtcacta tgtatgtaac tgacatatat aaatagtcat ttataaatga ccgtattata     1380

acatttgaaa aagtcttcat cattttcagt atttctctct gcattatttt ttagaagcaa     1440

ctcaaattct gtaatcataa tattaccaag taagtcagtc tttatttttg cgtgaaaatc     1500

ccaagtgtag aaaaaaggac atgagtataa gatcatttaa cttgattcct tataggctga     1560

tttgggttgc taatgtattc gtactagatt agccacttgg gaggaattca atgctgcatc     1620

attctgatag ctgaaatagt aaaagtcaac tccaaacagc ctaaattcta gtataaaaag     1680

ggggtgatca tacaagtcct aaagtgtaga tcagcagtca ctgaacctct tagagtcaca     1740

aggcatttct tctcccaaag tcatgacctt tatattttgt tagccttata attgactaac     1800

aaagcaacct gccaagttgg tgaaggttaa ttattgcctc atgaaatata cattcatcgc     1860

ataaaagaat taaataggaa gatggccaaa aatgtaaaaa agtcgtataa atttgtctaa     1920

gaagaaaaag acccaattta agtagtctgt gacttgactc ccaaattctg acctgatgga     1980

tgaaagtgaa gatgtttcgt atggcaaatt cagtaatgct acctcagtat atagttctgt     2040

atacgtattt ggaccaaagt tattagataa accaaaaata tttcatgaag catcttctgc     2100

ttcagagtcc atatccagcc acccagctat gaatgtattt agaaagatat ttggtggagg     2160

tggaatttct accagaggtc aagaggattt gtagggatag cctcaagaat gccagatgag     2220

tgtgtcagaa agcctgctcc tacctctcgc cagctgcgtg actttaggca agtcacttaa     2280

gtaccttatt tcagtttcct cacctgtaaa ttgaacaggg gttgaatgga ataaaaagcc     2340

ctttgcaact ctaaaagtca attaacacac ttactaaggt gttttaagtg accaggaagg     2400

aaatcagaac taacctggat tgttagcgaa gaaaacagaa gccaccaaca agcctatctg     2460

tcctttgcaa ttttgctcca agagcctatt agcaatttga attctgagcc tctaagaaaa     2520

cttatgctca ggtggcccct ccaagtgttg gtgccagagc actcttgcct tgtatcctca     2580

cctacgcctt ccatgaactc atagcagtgc tgtggcactg caggggtgtt ttatgcattc     2640

acgttaggag catgagcaga actgcatatg ccagcaccac atgggcagca gagactcccc     2700

actgccagat ggatgataat ggagctgcac tgggaacaac caggactgtc ccagtcaaca     2760

tgatacagat gaacatcctg ccttaagtca ctagctctct ccaaagccag ataaagtggg     2820

tttcttcact tacatctctc taatcttggc tgccttattc aacctacaga ctctatgtca     2880

gtgctggatt ttctcccctt gccctttagg taagcagagt aggcaggagg agatttgaaa     2940

gcgtgtcata catattgcct tgaaagaaag gacattcagg tgtcccttcg gggttctgta     3000

acaattaggc tatgtgtgct gagagaggga gcggagtcat ttgctgatgt gctgctacct     3060

gtaactcaaa tgcctcatag gaataccagc ggacaaacac atagaggaaa agttgaatct     3120

ttcctatatt ggacaatctt ccttcagtct tgtttctgca tcaaaaagtc tgggacacag     3180

agtgctacag gatgcctggg ctaaggactg taacagaaaa atatcaacat cagagcctgg     3240

cacagtggct cacaccggta atcccagcac tttgggaggc cgaggcgggt ggatcacttc     3300

aggtcaggag ttcgagacca tcctggccaa catggtgaaa cccccatctc tactaaaaat     3360

acaaaaatta gccgggcacg gtggcacatg cctgtaatcc cagctacctg ggaggctgag     3420

tcagaagaat cacttgaaaa caggaggctg aggttgcaat gagccaagat tgcaccactg     3480

cactccaacc tgggcaacag agcgagaccc catcttaaag accctgtctc aaaaaagaga     3540

gaaaaagaaa aagaaaaata tcaggcatca catgaaagag tattcagctg tcgttcttgt     3600

gaaaaaggaa aaggacaaaa tcaaatgcat tttaactgtg gtaactaatt cactgacttg     3660

aagtttgctt tgtttgtttt ctttggtgcg tagagaagaa tacttcatac taactcctga     3720

tcatcttaca gcagacataa caacagagtg ttagagactg gaataaatat gaatttggct     3780

gaaatgtgaa aaaaaaaaaa aaaaaa                                          3806


<210>  2197
<211>  4150
<212>  DNA
<213>  homo sapiens

<400>  2197
actcggtgcg ccttccgcgg accgggcgac ccagtgcacg gccgccgcgt cactctcggt       60

cccgctgacc ccgcgccgag ccccggcggc tctggccgcg gccgcactca gcgccacgcg      120

tcgaaagcgc aggccccgag gacccgccgc actgacagta tgagccgcac agcctacacg      180

gtgggagccc tgcttctcct cttggggacc ctgctgccgg ctgctgaagg gaaaaagaaa      240

gggtcccaag gtgccatccc cccgccagac aaggcccagc acaatgactc agagcagact      300

cagtcgcccc agcagcctgg ctccaggaac cgggggcggg gccaagggcg gggcactgcc      360

atgcccgggg aggaggtgct ggagtccagc caagaggccc tgcatgtgac ggagcgcaaa      420

tacctgaagc gagactggtg caaaacccag ccgcttaagc agaccatcca cgaggaaggc      480

tgcaacagtc gcaccatcat caaccgcttc tgttacggcc agtgcaactc tttctacatc      540

cccaggcaca tccggaagga ggaaggttcc tttcagtcct gctccttctg caagcccaag      600

aaattcacta ccatgatggt cacactcaac tgccctgaac tacagccacc taccaagaag      660

aagagagtca cacgtgtgaa gcagtgtcgt tgcatatcca tcgatttgga ttaagccaaa      720

tccaggtgca cccagcatgt cctaggaatg cagccccagg aagtcccaga cctaaaacaa      780

ccagattctt acttggctta aacctagagg ccagaagaac ccccagctgc ctcctggcag      840

gagcctgctt gtgcgtagtt cgtgtgcatg agtgtggatg ggtgcctgtg ggtgttttta      900

gacaccagag aaaacacagt ctctgctaga gagcactccc tattttgtaa acatatctgc      960

tttaatgggg atgtaccaga aacccacctc accccggctc acatctaaag gggcggggcc     1020

gtggtctggt tctgactttg tgtttttgtg ccctcctggg gaccagaatc tcctttcgga     1080

atgaatgttc atggaagagg ctcctctgag ggcaagagac ctgttttagt gctgcattcg     1140

acatggaaaa gtccttttaa cctgtgcttg catcctcctt tcctcctcct cctcacaatc     1200

catctcttct taagttgata gtgactatgt cagtctaatc tcttgtttgc caaggttcct     1260

aaattaattc acttaaccat gatgcaaatg tttttcattt tgtgaagacc ctccagactc     1320

tgggagaggc tggtgtgggc aaggacaagc aggatagtgg agtgagaaag ggagggtgga     1380

gggtgaggcc aaatcaggtc cagcaaaagt cagtagggac attgcagaag cttgaaaggc     1440

caataccaga acacaggctg atgcttctga gaaagtcttt tcctagtatt taacagaacc     1500

caagtgaaca gaggagaaat gagattgcca gaaagtgatt aactttggcc gttgcaatct     1560

gctcaaacct aacaccaaac tgaaaacata aatactgacc actcctatgt tcggacccaa     1620

gcaagttagc taaaccaaac caactcctct gctttgtccc tcaggtggaa aagagaggta     1680

gtttagaact ctctgcatag gggtgggaat taatcaaaaa cctcagaggc tgaaattcct     1740

aatacctttc ctttatcgtg gttatagtca gctcatttcc attccactat ttcccataat     1800

gcttctgaga gccactaact tgattgataa agatcctgcc tctgctgagt gtacctgaca     1860

gtagtctaag atgagagagt ttagggacta ctctgtttta gcaagagata ttttgggggt     1920

ctttttgttt taactattgt caggagattg ggctaaagag aagacgacga gagtaaggaa     1980

ataaagggaa ttgcctctgg ctagagagta gttaggtgtt aatacctggt agagatgtaa     2040

gggatatgac ctccctttct ttatgtgctc actgaggatc tgaggggacc ctgttaggag     2100

agcatagcat catgatgtat tagctgttca tctgctactg gttggatgga cataactatt     2160

gtaactattc agtatttact ggtaggcact gtcctctgat taaacttggc ctactggcaa     2220

tggctactta ggattgatct aagggccaaa gtgcagggtg ggtgaacttt attgtacttt     2280

ggatttggtt aacctgtttt cttcaagcct gaggttttat atacaaactc cctgaatact     2340

ctttttgcct tgtatcttct cagcctccta gccaagtcct atgtaatatg gaaaacaaac     2400

actgcagact tgagattcag ttgccgatca aggctctggc attcagagaa cccttgcaac     2460

tcgagaagct gtttttattt cgtttttgtt ttgatccagt gctctcccat ctaacaacta     2520

aacaggagcc atttcaaggc gggagatatt ttaaacaccc aaaatgttgg gtctgatttt     2580

caaactttta aactcactac tgatgattct cacgctaggc gaatttgtcc aaacacatag     2640

tgtgtgtgtt ttgtatacac tgtatgaccc caccccaaat ctttgtattg tccacattct     2700

ccaacaataa agcacagagt ggatttaatt aagcacacaa atgctaaggc agaattttga     2760

gggtgggaga gaagaaaagg gaaagaagct gaaaatgtaa aaccacacca gggaggaaaa     2820

atgacattca gaaccagcaa acactgaatt tctcttgttg ttttaactct gccacaagaa     2880

tgcaatttcg ttaacggaga tgacttaagt tggcagcagt aatcttcttt taggagcttg     2940

taccacagtc ttgcacataa gtgcagattt ggctcaagta aagagaattt cctcaacact     3000

aacttcactg ggataatcag cagcgtaact accctaaaag catatcacta gccaaagagg     3060

gaaatatctg ttcttcttac tgtgcctata ttaagactag tacaaatgtg gtgtgtcttc     3120

caactttcat tgaaaatgcc atatctatac catattttat tcgagtcact gatgatgtaa     3180

tgatatattt tttcattatt atagtagaat atttttatgg caagatattt gtggtcttga     3240

tcatacctat taaaataatg ccaaacacca aatatgaatt ttatgatgta cactttgtgc     3300

ttggcattaa aagaaaaaaa cacacatcct ggaagtctgt aagttgtttt ttgttactgt     3360

aggtcttcaa agttaagagt gtaagtgaaa aatctggagg agaggataat ttccactgtg     3420

tggaatgtga atagttaaat gaaaagttat ggttatttaa tgtaattatt acttcaaatc     3480

ctttggtcac tgtgatttca agcatgtttt ctttttctcc tttatatgac tttctctgag     3540

ttgggcaaag aagaagctga cacaccgtat gttgttagag tcttttatct ggtcagggga     3600

aacaaaatct tgacccagct gaacatgtct tcctgagtca gtgcctgaat ctttattttt     3660

taaattgaat gttccttaaa ggttaacatt tctaaagcaa tattaagaaa gactttaaat     3720

gttattttgg aagacttacg atgcatgtat acaaacgaat agcagataat gatgactagt     3780

tcacacataa agtcctttta aggagaaaat ctaaaatgaa aagtggataa acagaacatt     3840

tataagtgat cagttaatgc ctaagagtga aagtagttct attgacattc ctcaagatat     3900

ttaatatcaa ctgcattatg tattatgtct gcttaaatca tttaaaaacg gcaaagaatt     3960

atatagacta tgaggtacct tgctgtgtag gaggatgaaa ggggagttga tagtctcata     4020

aaactaattt ggcttcaagt ttcatgaatc tgtaactaga atttaatttt caccccaata     4080

atgttctata tagcctttgc taaagagcaa ctaataaatt aaacctattc tttctgtgaa     4140

aaaaaaaaaa                                                            4150


<210>  2198
<211>  4150
<212>  DNA
<213>  homo sapiens

<400>  2198
actcggtgcg ccttccgcgg accgggcgac ccagtgcacg gccgccgcgt cactctcggt       60

cccgctgacc ccgcgccgag ccccggcggc tctggccgcg gccgcactca gcgccacgcg      120

tcgaaagcgc aggccccgag gacccgccgc actgacagta tgagccgcac agcctacacg      180

gtgggagccc tgcttctcct cttggggacc ctgctgccgg ctgctgaagg gaaaaagaaa      240

gggtcccaag gtgccatccc cccgccagac aaggcccagc acaatgactc agagcagact      300

cagtcgcccc agcagcctgg ctccaggaac cgggggcggg gccaagggcg gggcactgcc      360

atgcccgggg aggaggtgct ggagtccagc caagaggccc tgcatgtgac ggagcgcaaa      420

tacctgaagc gagactggtg caaaacccag ccgcttaagc agaccatcca cgaggaaggc      480

tgcaacagtc gcaccatcat caaccgcttc tgttacggcc agtgcaactc tttctacatc      540

cccaggcaca tccggaagga ggaaggttcc tttcagtcct gctccttctg caagcccaag      600

aaattcacta ccatgatggt cacactcaac tgccctgaac tacagccacc taccaagaag      660

aagagagtca cacgtgtgaa gcagtgtcgt tgcatatcca tcgatttgga ttaagccaaa      720

tccaggtgca cccagcatgt cctaggaatg cagccccagg aagtcccaga cctaaaacaa      780

ccagattctt acttggctta aacctagagg ccagaagaac ccccagctgc ctcctggcag      840

gagcctgctt gtgcgtagtt cgtgtgcatg agtgtggatg ggtgcctgtg ggtgttttta      900

gacaccagag aaaacacagt ctctgctaga gagcactccc tattttgtaa acatatctgc      960

tttaatgggg atgtaccaga aacccacctc accccggctc acatctaaag gggcggggcc     1020

gtggtctggt tctgactttg tgtttttgtg ccctcctggg gaccagaatc tcctttcgga     1080

atgaatgttc atggaagagg ctcctctgag ggcaagagac ctgttttagt gctgcattcg     1140

acatggaaaa gtccttttaa cctgtgcttg catcctcctt tcctcctcct cctcacaatc     1200

catctcttct taagttgata gtgactatgt cagtctaatc tcttgtttgc caaggttcct     1260

aaattaattc acttaaccat gatgcaaatg tttttcattt tgtgaagacc ctccagactc     1320

tgggagaggc tggtgtgggc aaggacaagc aggatagtgg agtgagaaag ggagggtgga     1380

gggtgaggcc aaatcaggtc cagcaaaagt cagtagggac attgcagaag cttgaaaggc     1440

caataccaga acacaggctg atgcttctga gaaagtcttt tcctagtatt taacagaacc     1500

caagtgaaca gaggagaaat gagattgcca gaaagtgatt aactttggcc gttgcaatct     1560

gctcaaacct aacaccaaac tgaaaacata aatactgacc actcctatgt tcggacccaa     1620

gcaagttagc taaaccaaac caactcctct gctttgtccc tcaggtggaa aagagaggta     1680

gtttagaact ctctgcatag gggtgggaat taatcaaaaa cctcagaggc tgaaattcct     1740

aatacctttc ctttatcgtg gttatagtca gctcatttcc attccactat ttcccataat     1800

gcttctgaga gccactaact tgattgataa agatcctgcc tctgctgagt gtacctgaca     1860

gtagtctaag atgagagagt ttagggacta ctctgtttta gcaagagata ttttgggggt     1920

ctttttgttt taactattgt caggagattg ggctaaagag aagacgacga gagtaaggaa     1980

ataaagggaa ttgcctctgg ctagagagta gttaggtgtt aatacctggt agagatgtaa     2040

gggatatgac ctccctttct ttatgtgctc actgaggatc tgaggggacc ctgttaggag     2100

agcatagcat catgatgtat tagctgttca tctgctactg gttggatgga cataactatt     2160

gtaactattc agtatttact ggtaggcact gtcctctgat taaacttggc ctactggcaa     2220

tggctactta ggattgatct aagggccaaa gtgcagggtg ggtgaacttt attgtacttt     2280

ggatttggtt aacctgtttt cttcaagcct gaggttttat atacaaactc cctgaatact     2340

ctttttgcct tgtatcttct cagcctccta gccaagtcct atgtaatatg gaaaacaaac     2400

actgcagact tgagattcag ttgccgatca aggctctggc attcagagaa cccttgcaac     2460

tcgagaagct gtttttattt cgtttttgtt ttgatccagt gctctcccat ctaacaacta     2520

aacaggagcc atttcaaggc gggagatatt ttaaacaccc aaaatgttgg gtctgatttt     2580

caaactttta aactcactac tgatgattct cacgctaggc gaatttgtcc aaacacatag     2640

tgtgtgtgtt ttgtatacac tgtatgaccc caccccaaat ctttgtattg tccacattct     2700

ccaacaataa agcacagagt ggatttaatt aagcacacaa atgctaaggc agaattttga     2760

gggtgggaga gaagaaaagg gaaagaagct gaaaatgtaa aaccacacca gggaggaaaa     2820

atgacattca gaaccagcaa acactgaatt tctcttgttg ttttaactct gccacaagaa     2880

tgcaatttcg ttaacggaga tgacttaagt tggcagcagt aatcttcttt taggagcttg     2940

taccacagtc ttgcacataa gtgcagattt ggctcaagta aagagaattt cctcaacact     3000

aacttcactg ggataatcag cagcgtaact accctaaaag catatcacta gccaaagagg     3060

gaaatatctg ttcttcttac tgtgcctata ttaagactag tacaaatgtg gtgtgtcttc     3120

caactttcat tgaaaatgcc atatctatac catattttat tcgagtcact gatgatgtaa     3180

tgatatattt tttcattatt atagtagaat atttttatgg caagatattt gtggtcttga     3240

tcatacctat taaaataatg ccaaacacca aatatgaatt ttatgatgta cactttgtgc     3300

ttggcattaa aagaaaaaaa cacacatcct ggaagtctgt aagttgtttt ttgttactgt     3360

aggtcttcaa agttaagagt gtaagtgaaa aatctggagg agaggataat ttccactgtg     3420

tggaatgtga atagttaaat gaaaagttat ggttatttaa tgtaattatt acttcaaatc     3480

ctttggtcac tgtgatttca agcatgtttt ctttttctcc tttatatgac tttctctgag     3540

ttgggcaaag aagaagctga cacaccgtat gttgttagag tcttttatct ggtcagggga     3600

aacaaaatct tgacccagct gaacatgtct tcctgagtca gtgcctgaat ctttattttt     3660

taaattgaat gttccttaaa ggttaacatt tctaaagcaa tattaagaaa gactttaaat     3720

gttattttgg aagacttacg atgcatgtat acaaacgaat agcagataat gatgactagt     3780

tcacacataa agtcctttta aggagaaaat ctaaaatgaa aagtggataa acagaacatt     3840

tataagtgat cagttaatgc ctaagagtga aagtagttct attgacattc ctcaagatat     3900

ttaatatcaa ctgcattatg tattatgtct gcttaaatca tttaaaaacg gcaaagaatt     3960

atatagacta tgaggtacct tgctgtgtag gaggatgaaa ggggagttga tagtctcata     4020

aaactaattt ggcttcaagt ttcatgaatc tgtaactaga atttaatttt caccccaata     4080

atgttctata tagcctttgc taaagagcaa ctaataaatt aaacctattc tttctgtgaa     4140

aaaaaaaaaa                                                            4150


<210>  2199
<211>  5154
<212>  DNA
<213>  homo sapiens

<400>  2199
gcaaaatcag ccctccctcc tcccgctcct tcgccgcggc cctcccctcc tcgcgctgct       60

ctcgttcgct tggctcagct cagctcagct cagcgcagct ccgcggccgc caagccgagg      120

cgggcacggt ctccgagtcg cggacgccag ctccgagctc cctctctccg ccgcgcctcc      180

gccaggtcgc gccttcgtcg ggaccacttc gggcaggagt cgcgtggcga aggcctgcgg      240

ccgcggcaca aagttggggg ccgcgaagat gaggctgtcc ccggcgcccc tgaagctgag      300

ccggactccg gcactgctgg ccctggcgct gcccctggcc gcggcgctgg ccttctccga      360

cgagaccctg gacaaagtgc ccaagtcaga gggctactgc agccgtatcc tgcgcgccca      420

gggcacgcgg cgcgagggct acaccgagtt cagcctccgc gtggagggcg accccgactt      480

ctacaagccg ggaaccagct accgcgtaac actttcagct gctcctccct cctacttcag      540

aggattcaca ttaattgccc tcagagagaa cagagagggt gataaggaag aagaccatgc      600

tgggaccttc cagatcatag acgaagaaga aactcagttt atgagcaatt gccctgttgc      660

agtcactgaa agcactccac ggaggaggac ccggatccag gtgttttgga tagcaccacc      720

agcgggaaca ggctgcgtga ttctgaaggc cagcatcgta caaaaacgca ttatttattt      780

tcaagatgag ggctctctga ccaagaaact ttgtgaacaa gattccacat ttgatggggt      840

gactgacaaa cccatcttag actgctgtgc ctgcggaact gccaagtaca gactcacatt      900

ttatgggaat tggtccgaga agacacaccc aaaggattac cctcgtcggg ccaaccactg      960

gtctgcgatc atcggaggat cccactccaa gaattatgta ctgtgggaat atggaggata     1020

tgccagcgaa ggcgtcaaac aagttgcaga attgggctca cccgtgaaaa tggaggaaga     1080

aattcgacaa cagagtgatg aggtcctcac cgtcatcaaa gccaaagccc aatggccagc     1140

ctggcagcct ctcaacgtga gagcagcacc ttcagctgaa ttttccgtgg acagaacgcg     1200

ccatttaatg tccttcctga ccatgatggg ccctagtccc gactggaacg taggcttatc     1260

tgcagaagat ctgtgcacca aggaatgtgg ctgggtccag aaggtggtgc aagacctgat     1320

tccctgggac gctggcaccg acagcggggt gacctatgag tcacccaaca aacccaccat     1380

tccccaggag aaaatccggc ccctgaccag cctggaccat cctcagagtc ctttctatga     1440

cccagagggt gggtccatca ctcaagtagc cagagttgtc atcgagagaa tcgcacggaa     1500

gggtgaacaa tgcaatattg tacctgacaa tgtcgatgat attgtagctg acctggctcc     1560

agaagagaaa gatgaagatg acacccctga aacctgcatc tactccaact ggtccccatg     1620

gtccgcctgc agctcctcca cctgtgacaa aggcaagagg atgcgacagc gcatgctgaa     1680

agcacagctg gacctcagcg tcccctgccc tgacacccag gacttccagc cctgcatggg     1740

ccctggctgc agtgacgaag acggctccac ctgcaccatg tccgagtgga tcacctggtc     1800

gccctgcagc atctcctgcg gcatgggcat gaggtcccgg gagaggtatg tgaagcagtt     1860

cccggaggac ggctccgtgt gcacgctgcc cactgaggaa acggagaagt gcacggtcaa     1920

cgaggagtgc tctcccagca gctgcctgat gaccgagtgg ggcgagtggg acgagtgcag     1980

cgccacctgc ggcatgggca tgaagaagcg gcaccgcatg atcaagatga accccgcaga     2040

tggctccatg tgcaaagccg agacatcaca ggcagagaag tgcatgatgc cagagtgcca     2100

caccatccca tgcttgctgt ccccatggtc cgagtggagt gactgcagcg tgacctgcgg     2160

gaagggcatg cgaacccgac agcggatgct caagtctctg gcagaacttg gagactgcaa     2220

tgaggatctg gagcaggtgg agaagtgcat gctccctgaa tgccccattg actgtgagct     2280

caccgagtgg tcccagtggt cggaatgtaa caagtcatgt gggaaaggcc acgtgattcg     2340

aacccggatg atccaaatgg agcctcagtt tggaggtgca ccctgcccag agactgtgca     2400

gcgaaaaaag tgccgcatcc gaaaatgcct tcgaaatcca tccatccaaa agctacgctg     2460

gagggaggcc cgagagagcc ggcggagtga gcagctgaag gaagagtctg aaggggagca     2520

gttcccaggt tgtaggatgc gcccatggac ggcctggtca gaatgcacca aactgtgcgg     2580

aggtggaatt caggaacgtt acatgactgt aaagaagaga ttcaaaagct cccagtttac     2640

cagctgcaaa gacaagaagg agatcagagc atgcaatgtt catccttgtt agcaagggta     2700

cgagttcccc agggctgcac tctagattcc agagtcacca atggctggat tatttgcttg     2760

tttaagacaa tttaaattgt gtacgctagt tttcattttt gcagtgtggt tcgcccagta     2820

gtcttgtgga tgccagagac atcctttctg aatacttctt gatgggtaca ggctgagtgg     2880

ggcgccctca cctccagcca gcctcttcct gcagaggagt agtgtcagcc accttgtact     2940

aagctgaaac atgtccctct ggagcttcca cctggccagg gaggacggag actttgacct     3000

actccacatg gagaggcaac catgtctgga agtgactatg cctgagtccc agggtgcggc     3060

aggtaggaaa cattcacaga tgaagacagc agattcccca cattctcatc tttggcctgt     3120

tcaatgaaac cattgtttgc ccatctcttc ttagtggaac tttaggtctc ttttcaagtc     3180

tcctcagtca tcaatagttc ctggggaaaa acagagctgg tagacttgaa gaggagcatt     3240

gatgttgggt ggcttttgtt ctttcactga gaaattcgga atacatttgt ctcacccctg     3300

atattggttc ctgatgcccc cccaacaaaa ataaataaat aaattatggc tgctttattt     3360

aaatataagg tagctagttt ttacacctga gataaataat aagcttagag tgtatttttc     3420

ccttgctttt gggggttcag aggagtatgt acaattcttc tgggaagcca gccttctgaa     3480

ctttttggta ctaaatcctt attggaacca agacaaagga agcaaaattg gtctctttag     3540

agaccaattt gcctaaattt taaaatcttc ctacacacat ctagacgttc aagtttgcaa     3600

atcagttttt agcaagaaaa catttttgct atacaaacat tttgctaagt ctgcccaaag     3660

cccccccaat gcattccttc aacaaaatac aatctctgta ctttaaagtt attttagtca     3720

tgaaatttta tatgcagaga gaaaaagtta ccgagacaga aaacaaatct aagggaaagg     3780

aatattatgg gattaagctg agcaagcaat tctggtggaa agtcaaacct gtcagtgctc     3840

cacaccaggg ctgtggtcct cccagacatg cataggaatg gccacaggtt tacactgcct     3900

tcccagcaat tataagcaca ccagattcag ggagactgac caccaaggga tagtgtaaaa     3960

ggacattttc tcagttgggt ccatcagcag tttttcttcc tgcatttatt gttgaaaact     4020

attgtttcat ttcttctttt ataggcctta ttactgctta atccaaatgt gtaccattgg     4080

tgagacacat acaatgctct gaatacacta cgaatttgta ttaaacacat cagaatattt     4140

ccaaatacaa catagtatag tcctgaatat gtacttttaa cacaagagag actattcaat     4200

aaaaactcac tgggtctttc atgtctttaa gctaagtaag tgttcagaag gttctttttt     4260

atattgtcct ccacctccat cattttcaat aaaagatagg gcttttgctc ccttgttctt     4320

ggagggacca ttattacatc tctgaactac ctttgtatcc aacatgtttt aaatccttaa     4380

atgaattgct ttctcccaaa aaaagcacaa tataaagaaa cacaagattt aattattttt     4440

ctacttgggg ggaaaaaagt cctcatgtag aagcacccac ttttgcaatg ttgttctaag     4500

ctatctatct aactctcagc ccatgataaa gttccttaag ctggtgattc ctaatcaagg     4560

acaagccacc ctagtgtctc atgtttgtat ttggtcccag ttgggtacat tttaaaatcc     4620

tgattttgga gacttaaaac caggttaatg gctaagaatg ggtaacatga ctcttgttgg     4680

attgttattt tttgtttgca atggggaatt tataagaagc atcaagtctc tttcttacca     4740

aagtcttgtt aggtggttta tagttctttt ggctaacaaa tcattttgga aataaagatt     4800

ttttactaca aaaatgaaat ttgtttggac ttccacttga gacagtaaag agagtattag     4860

acacccagta aaaactgcca tataaagaag ttgtaattgt ttgttgtgta tgtatttttt     4920

tcaatgccaa accagctgtg atccaattta catccacatt ttaggtccaa cagcaagaag     4980

ttcagagaga gatttcccaa ccagacattg ggtcactcac tggtcacctt gccagtgcat     5040

tttattagaa gggaatctgt tgtagcaaat gggaataaac ctgggtttct atagacccag     5100

aactgaaaaa ataaacatcg tgctgttttt aatttgaaaa aaaaaaaaaa aaaa           5154


<210>  2200
<211>  5012
<212>  DNA
<213>  homo sapiens

<400>  2200
agcagagctg cggccggggg aacccagttt ccgaggaact tttcgccggc gccgggccgc       60

ctctgaggcc agggcaggac acgaacgcgc ggagcggcgg cggcgactga gagccggggc      120

cgcggcggcg ctccctagga agggccgtac gaggcggcgg gcccggcggg cctcccggag      180

gaggcggctg cgccatggac gagccaccct tcagcgaggc ggctttggag caggcgctgg      240

gcgagccgtg cgatctggac gcggcgctgc tgaccgacat cgaaggtgaa gtcggcgcgg      300

ggaggggtag ggccaacggc ctggacgccc caagggcggg cgcagatcgc ggagccatgg      360

attgcacttt cgaagacatg cttcagctta tcaacaacca agacagtgac ttccctggcc      420

tatttgaccc accctatgct gggagtgggg cagggggcac agaccctgcc agccccgata      480

ccagctcccc aggcagcttg tctccacctc ctgccacatt gagctcctct cttgaagcct      540

tcctgagcgg gccgcaggca gcgccctcac ccctgtcccc tccccagcct gcacccactc      600

cattgaagat gtacccgtcc atgcccgctt tctcccctgg gcctggtatc aaggaagagt      660

cagtgccact gagcatcctg cagaccccca ccccacagcc cctgccaggg gccctcctgc      720

cacagagctt cccagcccca gccccaccgc agttcagctc cacccctgtg ttaggctacc      780

ccagccctcc gggaggcttc tctacaggaa gccctcccgg gaacacccag cagccgctgc      840

ctggcctgcc actggcttcc ccgccagggg tcccgcccgt ctccttgcac acccaggtcc      900

agagtgtggt cccccagcag ctactgacag tcacagctgc ccccacggca gcccctgtaa      960

cgaccactgt gacctcgcag atccagcagg tcccggtcct gctgcagccc cacttcatca     1020

aggcagactc gctgcttctg acagccatga agacagacgg agccactgtg aaggcggcag     1080

gtctcagtcc cctggtctct ggcaccactg tgcagacagg gcctttgccg accctggtga     1140

gtggcggaac catcttggca acagtcccac tggtcgtaga tgcggagaag ctgcctatca     1200

accggctcgc agctggcagc aaggccccgg cctctgccca gagccgtgga gagaagcgca     1260

cagcccacaa cgccattgag aagcgctacc gctcctccat caatgacaaa atcattgagc     1320

tcaaggatct ggtggtgggc actgaggcaa agctgaataa atctgctgtc ttgcgcaagg     1380

ccatcgacta cattcgcttt ctgcaacaca gcaaccagaa actcaagcag gagaacctaa     1440

gtctgcgcac tgctgtccac aaaagcaaat ctctgaagga tctggtgtcg gcctgtggca     1500

gtggagggaa cacagacgtg ctcatggagg gcgtgaagac tgaggtggag gacacactga     1560

ccccaccccc ctcggatgct ggctcacctt tccagagcag ccccttgtcc cttggcagca     1620

ggggcagtgg cagcggtggc agtggcagtg actcggagcc tgacagccca gtctttgagg     1680

acagcaaggc aaagccagag cagcggccgt ctctgcacag ccggggcatg ctggaccgct     1740

cccgcctggc cctgtgcacg ctcgtcttcc tctgcctgtc ctgcaacccc ttggcctcct     1800

tgctgggggc ccgggggctt cccagcccct cagataccac cagcgtctac catagccctg     1860

ggcgcaacgt gctgggcacc gagagcagag atggccctgg ctgggcccag tggctgctgc     1920

ccccagtggt ctggctgctc aatgggctgt tggtgctcgt ctccttggtg cttctctttg     1980

tctacggtga gccagtcaca cggccccact caggccccgc cgtgtacttc tggaggcatc     2040

gcaagcaggc tgacctggac ctggcccggg gagactttgc ccaggctgcc cagcagctgt     2100

ggctggccct gcgggcactg ggccggcccc tgcccacctc ccacctggac ctggcttgta     2160

gcctcctctg gaacctcatc cgtcacctgc tgcagcgtct ctgggtgggc cgctggctgg     2220

caggccgggc agggggcctg cagcaggact gtgctctgcg agtggatgct agcgccagcg     2280

cccgagacgc agccctggtc taccataagc tgcaccagct gcacaccatg gggaagcaca     2340

caggcgggca cctcactgcc accaacctgg cgctgagtgc cctgaacctg gcagagtgtg     2400

caggggatgc cgtgtctgtg gcgacgctgg ccgagatcta tgtggcggct gcattgagag     2460

tgaagaccag tctcccacgg gccttgcatt ttctgacacg cttcttcctg agcagtgccc     2520

gccaggcctg cctggcacag agtggctcag tgcctcctgc catgcagtgg ctctgccacc     2580

ccgtgggcca ccgtttcttc gtggatgggg actggtccgt gctcagtacc ccatgggaga     2640

gcctgtacag cttggccggg aacccagtgg accccctggc ccaggtgact cagctattcc     2700

gggaacatct cttagagcga gcactgaact gtgtgaccca gcccaacccc agccctgggt     2760

cagctgatgg ggacaaggaa ttctcggatg ccctcgggta cctgcagctg ctgaacagct     2820

gttctgatgc tgcgggggct cctgcctaca gcttctccat cagttccagc atggccacca     2880

ccaccggcgt agacccggtg gccaagtggt gggcctctct gacagctgtg gtgatccact     2940

ggctgcggcg ggatgaggag gcggctgagc ggctgtgccc gctggtggag cacctgcccc     3000

gggtgctgca ggagtctgag agacccctgc ccagggcagc tctgcactcc ttcaaggctg     3060

cccgggccct gctgggctgt gccaaggcag agtctggtcc agccagcctg accatctgtg     3120

agaaggccag tgggtacctg caggacagcc tggctaccac accagccagc agctccattg     3180

acaaggccgt gcagctgttc ctgtgtgacc tgcttcttgt ggtgcgcacc agcctgtggc     3240

ggcagcagca gcccccggcc ccggccccag cagcccaggg caccagcagc aggccccagg     3300

cttccgccct tgagctgcgt ggcttccaac gggacctgag cagcctgagg cggctggcac     3360

agagcttccg gcccgccatg cggagggtgt tcctacatga ggccacggcc cggctgatgg     3420

cgggggccag ccccacacgg acacaccagc tcctcgaccg cagtctgagg cggcgggcag     3480

gccccggtgg caaaggaggc gcggtggcgg agctggagcc gcggcccacg cggcgggagc     3540

acgcggaggc cttgctgctg gcctcctgct acctgccccc cggcttcctg tcggcgcccg     3600

ggcagcgcgt gggcatgctg gctgaggcgg cgcgcacact cgagaagctt ggcgatcgcc     3660

ggctgctgca cgactgtcag cagatgctca tgcgcctggg cggtgggacc actgtcactt     3720

ccagctagac cccgtgtccc cggcctcagc acccctgtct ctagccactt tggtcccgtg     3780

cagcttctgt cctgcgtcga agctttgaag gccgaaggca gtgcaagaga ctctggcctc     3840

cacagttcga cctgcggctg ctgtgtgcct tcgcggtgga aggcccgagg ggcgcgatct     3900

tgaccctaag accggcggcc atgatggtgc tgacctctgg tggccgatcg gggcactgca     3960

ggggccgagc cattttgggg ggcccccctc cttgctctgc aggcacctta gtggcttttt     4020

tcctcctgtg tacagggaag agaggggtac atttccctgt gctgacggaa gccaacttgg     4080

ctttcccgga ctgcaagcag ggctctgccc cagaggcctc tctctccgtc gtgggagaga     4140

gacgtgtaca tagtgtaggt cagcgtgctt agcctcctga cctgaggctc ctgtgctact     4200

ttgccttttg caaactttat tttcatagat tgagaagttt tgtacagaga attaaaaatg     4260

aaattattta taatctgggt tttgtgtctt cagctgatgg atgtgctgac tagtgagagt     4320

gcttgggccc tcccccagca cctagggaaa ggcttcccct ccccctccgg ccacaaggta     4380

cacaactttt aacttagctc ttcccgatgt ttgtttgtta gtgggaggag tggggagggc     4440

tggctgtatg gcctccagcc tacctgttcc ccctgctccc agggcacatg gttgggctgt     4500

gtcaaccctt agggcctcca tggggtcagt tgtcccttct cacctcccag ctctgtcccc     4560

atcaggtccc tgggtggcac gggaggatgg actgacttcc aggacctgtt gtgtgacagg     4620

agctacagct tgggtctccc tgcaagaagt ctggcacgtc tcacctcccc catcccggcc     4680

cctggtcatc tcacagcaaa gaagcctcct ccctcccgac ctgccgccac actggagagg     4740

gggcacaggg gcgggggagg tttcctgttc tgtgaaaggc cgactccctg actccattca     4800

tgcccccccc cccagcccct cccttcattc ccattcccca acctaaagcc tggcccggct     4860

cccagctgaa tctggtcgga atccacgggc tgcagatttt ccaaaacaat cgttgtatct     4920

ttattgactt tttttttttt ttttttctga atgcaatgac tgttttttac tcttaaggaa     4980

aataaacatc ttttagaaac aaaaaaaaaa aa                                   5012


<210>  2201
<211>  2471
<212>  DNA
<213>  homo sapiens

<400>  2201
gcgttacagg ccctttggcg cctgcgtatt cgtgaagtgt gaaaaaagcg cgcctctgtt       60

gggacgggaa atcagccttt ctattggtca gggttagaaa ccccgccttt gaggcatttt      120

caaccaatgg aagcgcggca ttcttcattt aaactgtcta taaatttctg cctagtcaaa      180

gttaagagtg gcgccaggga tttgaaccgc gctgacgaag tttggtgatc catcttccga      240

gtatcgccgg gatttcgaat cgcgatgatc atcccctctc tagaggagct ggactccctc      300

aagtacagtg acctgcagaa cttagccaag agtctgggtc tccgggccaa cctgagggca      360

accaagttgt taaaagcctt gaaaggctac attaaacatg aggcaagaaa aggaaatgag      420

aatcaggatg aaagtcaaac ttctgcatcc tcttgtgatg agactgagat acagatcagc      480

aaccaggaag aagctgagag acagccactt ggccatgtca ccaaaacaag gagaaggtgc      540

aagactgtcc gtgtggaccc tgactcacag cagaatcatt cagagataaa aataagtaat      600

cccactgaat tccagaatca tgaaaagcag gaaagccagg atctcagagc tactgcaaaa      660

gttccttctc caccagacga gcaccaagaa gctgagaatg ctgtttcctc aggtaacaga      720

gattcaaagg taccttcaga aggaaagaaa tctctctaca cagatgagtc atccaaacct      780

ggaaaaaata aaagaactgc aatcactact ccaaacttta agaagcttca tgaagctcat      840

tttaaggaaa tggagtccat tgatcaatat attgagagaa aaaagaaaca ttttgaagaa      900

cacaattcca tgaatgaact gaagcagcag cccatcaata agggaggggt caggactcca      960

gtacctccaa gaggaagact ctctgtggct tctactccca tcagccaacg acgctcgcaa     1020

ggccggtctt gtggccctgc aagtcagagt accttgggtc tgaaggggtc actcaagcgc     1080

tctgctatct ctgcagctaa aacgggtgtc aggttttcag ctgctactaa agataatgag     1140

cataagcgtt cactgaccaa gactccagcc agaaagtctg cacatgtgac cgtgtctggg     1200

ggcaccccaa aaggcgaggc tgtgcttggg acacacaaat taaagaccat cacggggaat     1260

tctgctgctg ttattacccc attcaagttg acaactgagg caacgcagac tccagtctcc     1320

aataagaaac cagtgtttga tcttaaagca agtttgtctc gtcccctcaa ctatgaacca     1380

cacaaaggaa agctaaaacc atgggggcaa tctaaagaaa ataattatct aaatcaacat     1440

gtcaacagaa ttaacttcta caagaaaact tacaaacaac cccatctcca gacaaaggaa     1500

gagcaacgga agaaacgcga gcaagaacga aaggagaaga aagcaaaggt tttgggaatg     1560

cgaaggggcc tcattttggc tgaagattaa taatttttta acatcttgta aatattcctg     1620

tattctcaac ttttttcctt ttgtaaattt tttttttttg ctgtcatccc cactttagtc     1680

acgagatctt tttctgctaa ctgttcatag tctgtgtagt gtccatgggt tcttcatgtg     1740

ctatgatctc tgaaaagacg ttatcacctt aaagctcaaa ttctttggga tggtttttac     1800

ttaagtccat taacaattca ggtttctaac gagacccatc ctaaaattct gtttctagat     1860

ttttaatgtc aagttcccaa gttccccctg ctggttctaa tattaacaga actgcagtct     1920

tctgctagcc aatagcattt acctgatggc agctagttat gcaagcttca ggagaatttg     1980

aacaataaca agaatagggt aagctgggat agaaaggcca cctcttcact ctctatagaa     2040

tatagtaacc tttatgaaac ggggccatat agtttggtta tgacatcaat attttaccta     2100

ggtgaaattg tttaggctta tgtaccttcg ttcaaatatc ctcatgtaat tgccatctgt     2160

cactcactat attcacaaaa ataaaactct acaactcatt ctaacattgc ttacttaaaa     2220

gctacatagc cctatcgaaa tgcgaggatt aatgctttaa tgcttttaga gacagggtct     2280

cactgtgttg cccaggctgg tctcaaactc caccaaatgt acttcttatt cattttatgg     2340

aaaagactag gctttgctta gtatcatgtc catgtttcct tcacctcagt ggagcttctg     2400

agttttatac tgctcaagat cgtcataaat aaaatttttt ctcattgtca tagaaaaaaa     2460

aaaaaaaaaa a                                                          2471


<210>  2202
<211>  940
<212>  DNA
<213>  homo sapiens

<400>  2202
ggtgtaaaca agtccaggcg cctgcgaacc cgggcccggg ggggacggcg cccgccagga       60

gcgcccccca ctcccaggcc agcccacccc ggcggaccgg gccccgcgcg cccaggcgag      120

gcactgggct ccctctgctc cccgtgggcc gctccccgcg tggggccact gcccccggcc      180

cccgccatgg tgcggatttc aaagcccaag acgtttcagg cctacttgga tgattgtcac      240

cggaggtata gctgtgccca ctgccgcgct cacctggcca accacgacga cctcatctcc      300

aagtccttcc agggcagtca ggggcgtgcc tacctcttca actcagtggt gaacgtgggc      360

tgcgggccag ccgaggagcg ggtgctgctg accggcctcc atgctgtcgc cgacatccac      420

tgcgagaact gcaagaccac tttgggctgg aaatatgaac aggcctttga gagcagccag      480

aagtacaaag aggggaagta catcattgaa ctcaaccaca tgatcaaaga caacggctgg      540

gactgacccc cgctcccccg acgcatgtgg ctccagcccg gcctggccgc cagggagcgc      600

cactggcttc ccgccacccg aagggagctc tggaccctca gagcccctgc agaggacgga      660

tctagctcct gtatatatat tttattgcat gcactgtgac cttgggggga gaacagaagg      720

gggacgacgc ccccgcacct cctgcgatct ggctggcttg gatctcgttt ttaacccgtt      780

cctgccccac ctgccctata gttatggcct gtgttctgct ctcctggtcc cagtgcaccg      840

tctgctctgt gaactcctcc caccaggccc ttcttacccc acgcgtgtct gtccccctcg      900

ttctgtagcg tttgtacata ataaaacaat ggagtggaga                            940


<210>  2203
<211>  2722
<212>  DNA
<213>  homo sapiens

<400>  2203
ttggcgcgta aaagtggccg ggactttgca ggcagcggcg gccgggggcg gagcgggatc       60

gagccctcgc cgaggcctgc cgccatgggc ccgcgccgcc gccgccgcct gtcacccggg      120

ccgcgcgggc cgtgagcgtc atggccttgg ccggggcccc tgcgggcggc ccatgcgcgc      180

cggcgctgga ggccctgctc ggggccggcg cgctgcggct gctcgactcc tcgcagatcg      240

tcatcatctc cgccgcgcag gacgccagcg ccccgccggc tcccaccggc cccgcggcgc      300

ccgccgccgg cccctgcgac cctgacctgc tgctcttcgc cacaccgcag gcgccccggc      360

ccacacccag tgcgccgcgg cccgcgctcg gccgcccgcc ggtgaagcgg aggctggacc      420

tggaaactga ccatcagtac ctggccgaga gcagtgggcc agctcggggc agaggccgcc      480

atccaggaaa aggtgtgaaa tccccggggg agaagtcacg ctatgagacc tcactgaatc      540

tgaccaccaa gcgcttcctg gagctgctga gccactcggc tgacggtgtc gtcgacctga      600

actgggctgc cgaggtgctg aaggtgcaga agcggcgcat ctatgacatc accaacgtcc      660

ttgagggcat ccagctcatt gccaagaagt ccaagaacca catccagtgg ctgggcagcc      720

acaccacagt gggcgtcggc ggacggcttg aggggttgac ccaggacctc cgacagctgc      780

aggagagcga gcagcagctg gaccacctga tgaatatctg tactacgcag ctgcgcctgc      840

tctccgagga cactgacagc cagcgcctgg cctacgtgac gtgtcaggac cttcgtagca      900

ttgcagaccc tgcagagcag atggttatgg tgatcaaagc ccctcctgag acccagctcc      960

aagccgtgga ctcttcggag aactttcaga tctcccttaa gagcaaacaa ggcccgatcg     1020

atgttttcct gtgccctgag gagaccgtag gtgggatcag ccctgggaag accccatccc     1080

aggaggtcac ttctgaggag gagaacaggg ccactgactc tgccaccata gtgtcaccac     1140

caccatcatc tcccccctca tccctcacca cagatcccag ccagtctcta ctcagcctgg     1200

agcaagaacc gctgttgtcc cggatgggca gcctgcgggc tcccgtggac gaggaccgcc     1260

tgtccccgct ggtggcggcc gactcgctcc tggagcatgt gcgggaggac ttctccggcc     1320

tcctccctga ggagttcatc agcctttccc caccccacga ggccctcgac taccacttcg     1380

gcctcgagga gggcgagggc atcagagacc tcttcgactg tgactttggg gacctcaccc     1440

ccctggattt ctgacagggc ttggagggac cagggtttcc agagatgctc accttgtctc     1500

tgcagccctg gagccccctg tccctggccg tcctcccagc ctgtttggaa acatttaatt     1560

tatacccctc tcctctgtct ccagaagctt ctagctctgg ggtctggcta ccgctaggag     1620

gctgagcaag ccaggaaggg aaggagtctg tgtggtgtgt atgtgcatgc agcctacacc     1680

cacacgtgtg taccgggggt gaatgtgtgt gagcatgtgt gtgtgcatgt accggggaat     1740

gaaggtgaac atacacctct gtgtgtgcac tgcagacacg ccccagtgtg tccacatgtg     1800

tgtgcatgag tccatgtgtg cgcgtggggg ggctctaact gcactttcgg cccttttgct     1860

ctgggggtcc cacaaggccc agggcagtgc ctgctcccag aatctggtgc tctgaccagg     1920

ccaggtgggg aggctttggc tggctgggcg tgtaggacgg tgagagcact tctgtcttaa     1980

aggttttttc tgattgaagc tttaatggag cgttatttat ttatcgaggc ctctttggtg     2040

agcctgggga atcagcaaag gggaggaggg gtgtggggtt gataccccaa ctccctctac     2100

ccttgagcaa gggcaggggt ccctgagctg ttcttctgcc ccatactgaa ggaactgagg     2160

cctgggtgat ttatttattg ggaaagtgag ggagggagac agactgactg acagccatgg     2220

gtggtcagat ggtggggtgg gccctctcca gggggccagt tcagggcccc agctgccccc     2280

caggatggat atgagatggg agaggtgagt gggggacctt cactgatgtg ggcaggaggg     2340

gtggtgaagg cctcccccag cccagaccct gtggtccctc ctgcagtgtc tgaagcgcct     2400

gcctccccac tgctctgccc caccctccaa tctgcacttt gatttgcttc ctaacagctc     2460

tgttccctcc tgctttggtt ttaataaata ttttgatgac gtttgggccg ggttttggga     2520

ctctgttggg aacatttcgg ggcgggagag gccaaggttg ctggggaaat gcccattctc     2580

cacttccctt ctccctgtcc gtgcccgatt tgatttgagc ctcataactc gaagaaaggt     2640

cagcttcctc gctgttttgg tcctaactca aaagcagatc cagtaaaggt ttttgttgta     2700

aaaaaaaaaa aaaaaaaaaa aa                                              2722


<210>  2204
<211>  1634
<212>  DNA
<213>  homo sapiens

<400>  2204
gggtggggaa gcttagagac cggtgaggga gcagagctgg ggcgcctgtg tacagggata       60

gagcccggcg gcagcagggc gcggcttccc tttcccgggg cctggggccg caatcaggtg      120

gagtcgagag gccggaggag gggcaggagg aaggggtgcg gtcgcgatcc ggacccggag      180

ccagcgcgga gcacctgcgc ccgcggctga caccttcgct cgcagtttgt tcgcagttta      240

ctcgcacacc agtttccccc accgcgcttt ggattagtgt gatctcagct caaggcaaag      300

gtgggatatc atggcatcta tctgggttgg acaccgagga acagtaagag attatccaga      360

ctttagccca tcagtggatg ctgaagctat tcagaaagca atcagaggaa ttggaactga      420

tgagaaaatg ctcatcagca ttctgactga gaggtcaaat gcacagcggc agctgattgt      480

taaggaatat caagcagcat atggaaagga gctgaaagat gacttgaagg gtgatctctc      540

tggccacttt gagcatctca tggtggccct agtgactcca ccagcagtct ttgatgcaaa      600

gcagctaaag aaatccatga agggcgcggg aacaaacgaa gatgccttga ttgaaatctt      660

aactaccagg acaagcaggc aaatgaagga tatctctcaa gcctattata cagtatacaa      720

gaagagtctt ggagatgaca ttagttccga aacatctggt gacttccgga aagctctgtt      780

gactttggca gatggcagaa gagatgaaag tctgaaagtg gatgagcatc tggccaaaca      840

agatgcccag attctctata aagctggtga gaacagatgg ggcacggatg aagacaaatt      900

cactgagatc ctgtgtttaa ggagctttcc tcaattaaaa ctaacatttg atgaatacag      960

aaatatcagc caaaaggaca ttgtggacag cataaaagga gaattatctg ggcattttga     1020

agacttactg ttggccatag ttaattgtgt gaggaacacg ccggcctttt tagccgaaag     1080

actgcatcga gccttgaagg gtattggaac tgatgagttt actctgaacc gaataatggt     1140

gtccagatca gaaattgacc ttttggacat tcgaacagag ttcaagaagc attatggcta     1200

ttccctatat tcagcaatta aatcggatac ttctggagac tatgaaatca cactcttaaa     1260

aatctgtggt ggagatgact gaaccaagaa gataatctcc aaaggtccac gatgggcttt     1320

cccaacagct ccaccttact tcttctcata ctatttaaga gaacaagcaa atataaacag     1380

caacttgtgt tcctaacagg aattttcatt gttctataac aacaacaaca aaagcgatta     1440

ttattttaga gcatctcatt tataatgtag cagctcataa atgaaattga aaatggtatt     1500

aaagatctgc aactactatc caacttatat ttctgctttc aaagttaaga atctttatag     1560

ttctactcca ttaaatataa agcaagataa taaaaattgt tgcttttgtt aaaagtaaaa     1620

aaaaaaaaaa aaaa                                                       1634


<210>  2205
<211>  2752
<212>  DNA
<213>  homo sapiens

<400>  2205
atgtgggggc gcacggcgcg gcggcgctgc ccgcgggaac tgcggcgcgg ccgggaggcg       60

ctgttggtgc tcctggcgct actggcgttg gccgggctgg gctcggtgct gcgggcgcag      120

cgtggggccg gggccggggc tgccgagccg ggacccccgc gcaccccgcg ccccgggcgg      180

cgcgagccgg tcatgccgcg gccgccggtg ccggcgaacg cgctgggcgc gcggggcgag      240

gcggtgcggc tgcagctgca gggcgaggag ctgcggctgc aggaggagag cgtgcggctg      300

caccagatta acatctacct cagcgaccgc atctcactgc accgccgcct gcccgagcgc      360

tggaacccgc tgtgcaaaga gaagaaatat gattatgata atttgcccag gacatctgtt      420

atcatagcat tttataatga agcctggtca actctccttc ggacagttta cagtgtcctt      480

gagacatccc cggatatcct gctagaagaa gtgatccttg tagatgacta cagtgataga      540

gagcacctga aggagcgctt ggccaatgag ctttcgggac tgcccaaggt gcgcctgatc      600

cgcgccaaca agagagaggg cctggtgcga gcccggctgc tgggggcgtc tgcggcgagg      660

ggcgatgttc tgaccttcct ggactgtcac tgtgagtgcc acgaagggtg gctggagccg      720

ctgctgcaga ggatccatga agaggagtcg gcagtggtgt gcccggtgat tgatgtgatc      780

gactggaaca ccttcgaata cctggggaac tccggggagc cccagatcgg cggtttcgac      840

tggaggctgg tgttcacgtg gcacacagtt cctgagaggg agaggatacg gatgcaatcc      900

cccgtcgatg tcatcaggtc tccaacaatg gctggtgggc tgtttgctgt gagtaagaaa      960

tattttgaat atctggggtc ttatgataca ggaatggaag tttggggagg agaaaacctc     1020

gaattttcct ttaggatctg gcagtgtggt ggggttctgg aaacacaccc atgttcccat     1080

gttggccatg ttttccccaa gcaagctccc tactcccgca acaaggctct ggccaacagt     1140

gttcgtgcag ctgaagtatg gatggatgaa tttaaagagc tctactacca tcgcaacccc     1200

cgtgcccgct tggaaccttt tggggatgtg acagagagga agcagctccg ggacaagctc     1260

cagtgtaaag acttcaagtg gttcttggag actgtgtatc cagaactgca tgtgcctgag     1320

gacaggcctg gcttcttcgg gatgctccag aacaaaggac taacagacta ctgctttgac     1380

tataaccctc ccgatgaaaa ccagattgtg ggacaccagg tcattctgta cctctgtcat     1440

gggatgggcc agaatcagtt tttcgagtac acgtcccaga aagaaatacg ctataacacc     1500

caccagcctg agggctgcat tgctgtggaa gcaggaatgg atacccttat catgcatctc     1560

tgcgaagaaa ctgccccaga gaatcagaag ttcatcttgc aggaggatgg atctttattt     1620

cacgaacagt ccaagaaatg tgtccaggct gcgaggaagg agtcgagtga cagtttcgtt     1680

ccactcttac gagactgcac caactcggat catcagaaat ggttcttcaa agagcgcatg     1740

ttatgaagcc tcgtgtatca aggagcccat cgaaggagac tgtggagcca ggactctgcc     1800

caacaaagac ttagctaagc agtgaccaga acccaccaaa aactaggctg cattgctttg     1860

aagaggcaat cattttgcca tttgtgaaag ttgtgttgga tttagtaaaa atgtgaataa     1920

gctttgtact tattttgaga actttttaaa tgttccaaaa taccctattt tcaaagggta     1980

atcgtaagat gttaaccctt ggtatttaga aaattaaaac cttataatat ttttctatca     2040

agatgtatat tttacagtcg tgccttttac tctcattagc aaaaaagata aagattttat     2100

tttggtattt acaagaattc ccaggtacga agatatctgc atgggtggaa atcaggttca     2160

agcaacgtac tttgcattaa ctgataatac ctcagctgcg gggttaaagt tttcccagta     2220

tagagagact gtcactagga acattgtatt gatttattca ggtcattgag atcttctaga     2280

tgtattttaa aaagaatgct ttttggttat gtgttgctac cacagttaac actccataat     2340

gttcatgtca gccaaagagg actaaccaaa gctgaaatct cagagaacaa tttgctttac     2400

taagctgagt caacttgaga gcgaacttct aacaatgccg cactgtagtg tggctggttc     2460

taccactatg actttaaaac atgtttatat catttttaat ttttatgata cggtagtgtc     2520

agggagaaat gtaatgttct atatgaaatt cctttttcaa gtttgttcat taataacagt     2580

tattaattta aatcagcgtt agagtttgtg ctgctgcaac tgctgtgaaa atttctctga     2640

gtaattctga tttgtgaatg atcccagacc aaccctgaga ttttgtcaac ctgattaagt     2700

caatatgaat gattaaaaag atgtgagaac actgaaaaaa aaaaaaaaaa aa             2752


<210>  2206
<211>  2717
<212>  DNA
<213>  homo sapiens

<400>  2206
gcgcttccgg tgcgacgctg tctctccatg ccaggactga gttgtggggg agggaggcgg       60

ttagcgggct ttagcgcctt ttctggcggc ggtagatttg aagcgcttca aaggaccgga      120

cccagagaag aggaaaactc taccggtgca ggagcacagg gatcagttgt ccttgttttt      180

ttttggtctt ttcttcattt gaagattaag tattggagcc atgggaataa aggttcaacg      240

tcctcgatgt ttttttgaca ttgccattaa caatcaacct gctggaagag ttgtctttga      300

attattttct gatgtgtgcc ccaaaacatg cgagaacttt cgttgtcttt gtacaggtga      360

aaaggggacc gggaaatcaa ctcagaaacc attacattat aagagttgtc tctttcacag      420

agttgtcaag gattttatgg ttcaaggtgg tgacttcagt gaaggaaatg gacgaggagg      480

ggaatctatc tatggaggat tttttgaaga cgagagtttc gctgttaaac acaacaaaga      540

atttctcttg tcaatggcca acagagggaa ggatacaaat ggttcacagt tcttcataac      600

aacgaaacca actcctcatt tagatgggca tcatgttgtt tttggacaag taatctctgg      660

tcaagaagtt gtaagagaga ttgaaaacca gaaaacagat gcagctagca aaccgtttgc      720

ggaggtacgg atactcagtt gtggagagct gattcccaaa tctaaagtta agaaagaaga      780

aaagaaaagg cataaatcat catcatcttc ctcctcctca tctagtgact cagatagctc      840

aagtgattct cagtcctctt ctgattcctc tgattccgaa agtgctactg aagagaaatc      900

aaagaaaaga aaaaagaaac atcggaaaaa ttcccgaaaa cacaagaaag aaaagaaaaa      960

gcgaaagaaa agcaagaaga gtgcatctag tgagagtgaa gctgaaaatc ttgaagcaca     1020

accccagtct actgtccgtc cagaagagat ccctcctata cctgaaaata gattcctaat     1080

gagaaaaagt cctcctaaag ctgatgagaa ggaaaggaaa aacagagaga gagaaaggga     1140

aagagagtgt aatccaccta actcccagcc tgcttcatac cagagacgac ttttagttac     1200

tagatctggc aggaaaatta aaggaagagg accaaggcgt tatcgaactc cttccagatc     1260

cagatcaagg gatcgtttca gacgtagtga gactcctcca cattggaggc aagagatgca     1320

gagagctcaa agaatgaggg tatcaagtgg tgaaagatgg atcaaggggg ataagagtga     1380

gttgaatgaa ataaaagaaa atcagagaag tccagttaga gtaaaagaga gaaaaataac     1440

agatcacagg aatgtatctg agagtccaaa cagaaaaaat gaaaaggaga agaaagttaa     1500

agaccataaa tctaacagca aagagagaga catcagaaga aattcagaaa aagatgacaa     1560

gtataaaaac aaagtgaaga aaagggccaa atctaaaagt aggagtaaga gcaaagagaa     1620

atcaaagagt aaagaaagag attcaaaaca taatagaaat gaagaaaaga ggatgaggtc     1680

aaggagtaaa ggaagggatc atgaaaatgt taaagaaaaa gaaaagcagt ctgattctaa     1740

aggaaaagat caggaaagga gtagaagtaa agagaagtct aaacagttag aatcaaagag     1800

taatgagcat gatcacagta aaagtaagga aaaggataga cgcgcacaat ccaggagtag     1860

agaatgtgat ataactaaag gtaaacacag ttataatagc agaacaagag aacgaagcag     1920

aagtagggac agaagcagaa gagtgcgatc aagaacccat gacagagatc gcagcagaag     1980

caaggagtac catagataca gagaacagga atacaggaga agaggacggt cacgaagccg     2040

agagagaaga acaccaccag gaagatcaag aagtaaagat aggaggagaa ggaggagaga     2100

ctcacggagc tcagagagag aagaaagtca aagcagaaac aaagacaaat acagaaacca     2160

agagagtaag agctcacaca gaaaagaaaa ttctgagagt gagaaaagaa tgtactctaa     2220

aagtcgtgat cataatagct caaataacag cagggaaaaa aaggctgata gagatcaaag     2280

tcccttctca aaaataaaac aaagcagtca ggacaatgaa ttaaagtcct ccatgttgaa     2340

aaataaggag gatgagaaga tcagatcctc agtggaaaaa gaaaaccaaa aatcaaaagg     2400

tcaagaaaat gaccatgtac atgaaaaaaa taaaaaattt gatcatgaat caagccctgg     2460

aacagatgaa gacaaaagcg gatgagtgag ttatataaac ttacttccat tctgtttcgg     2520

attttaagtt tgagagactt gctaatgaat ctcctttatg ttgttttcct tttcattgtt     2580

tttggattgt tttatgtttg tccttttttt tcttaatgtg gatttcattg agttgatttt     2640

ttgataatct gcaatctgga taatttgtac tgctaaagtt ttaataaact cgacatgaga     2700

aaaacaaaaa aaaaaaa                                                    2717


<210>  2207
<211>  2098
<212>  DNA
<213>  homo sapiens

<400>  2207
ttgggaaggg tttccagaag gtgggaaatg tcacctgatt cacactgaac ttttgaaagc       60

tccccacccc caaggagccg cgcacaccct cgctcgcggc cgccctccca cagccccaca      120

cactgggaga ccgcccaccg caaaccgcgg agacccccgt ctagatttaa agcgcggctg      180

cgcccggctt ctgacgtcca ttgaatcgcg cgggcggccg gcggcgagcg cggggctgcg      240

ccgggatcgc tgcgccctcc gccgctggcc tctgcgacgc gcgccgctcg cccgagccac      300

ccgccgccgc gccggctccc cgcgccgctg cgctcctcgc cccgcgcctg cccccaggat      360

ggtccgcgcg aggcaccagc cgggtgggct ttgcctcctg ctgctgctgc tctgccagtt      420

catggaggac cgcagtgccc aggctgggaa ctgctggctc cgtcaagcga agaacggccg      480

ctgccaggtc ctgtacaaga ccgaactgag caaggaggag tgctgcagca ccggccggct      540

gagcacctcg tggaccgagg aggacgtgaa tgacaacaca ctcttcaagt ggatgatttt      600

caacgggggc gcccccaact gcatcccctg taaagaaacg tgtgagaacg tggactgtgg      660

acctgggaaa aaatgccgaa tgaacaagaa gaacaaaccc cgctgcgtct gcgccccgga      720

ttgttccaac atcacctgga agggtccagt ctgcgggctg gatgggaaaa cctaccgcaa      780

tgaatgtgca ctcctaaagg caagatgtaa agagcagcca gaactggaag tccagtacca      840

aggcagatgt aaaaagactt gtcgggatgt tttctgtcca ggcagctcca catgtgtggt      900

ggaccagacc aataatgcct actgtgtgac ctgtaatcgg atttgcccag agcctgcttc      960

ctctgagcaa tatctctgtg ggaatgatgg agtcacctac tccagtgcct gccacctgag     1020

aaaggctacc tgcctgctgg gcagatctat tggattagcc tatgagggaa agtgtatcaa     1080

agcaaagtcc tgtgaagata tccagtgcac tggtgggaaa aaatgtttat gggatttcaa     1140

ggttgggaga ggccggtgtt ccctctgtga tgagctgtgc cctgacagta agtcggatga     1200

gcctgtctgt gccagtgaca atgccactta tgccagcgag tgtgccatga aggaagctgc     1260

ctgctcctca ggtgtgctac tggaagtaaa gcactccgga tcttgcaact gaatctgccc     1320

gtaaaacctg agccattgat tcttcagaac tttctgcagt ttttgacttc atagattatg     1380

ctttaaaaaa atttttttaa cttattgcat aacagcagat gccaaaaaca aaaaaagcat     1440

ctcactgcaa gtcacataaa aatgcaacgc tgtaatatgg ctgtatcaga gggctttgaa     1500

aacatacact gagctgcttc tgcgctgttg ttgtccgtat ttaaacaaca gctcccctgt     1560

attcccccat ctagccattt cggaagacac cgaggaagag gaggaagatg aagaccagga     1620

ctacagcttt cctatatctt ctattctaga gtggtaaact ctctataagt gttcagtgtt     1680

gacatagcct ttgtgcaaaa aaaaaaaaaa aaaaaaagaa aaagaaaaaa agaaaaatat     1740

attgtccata ctgtaaataa gtgtatgctt atttatttgg ggggaaaact atacattaaa     1800

ggacctttgt cctaaagctc tctcccaggc caccttgtta ctcattggac acggagaggc     1860

attcattgtg aggtctactg gatgaggccc atagttgaga cttgtagaca tttatttata     1920

ctgtgtcatg ttttataatt tatacataaa atgtctggtt gactgtatac cttgtttttg     1980

aagaaattta ttcgtgaaag gaagagcagt tgttatttat tgtgaggtct cttgcttgta     2040

aagtaaaagc tttttttcct tgtaaaccat ttaagtccat tccttactat tcactcac       2098


<210>  2208
<211>  1834
<212>  DNA
<213>  homo sapiens

<400>  2208
ttgggaaggg tttccagaag gtgggaaatg tcacctgatt cacactgaac ttttgaaagc       60

tccccacccc caaggagccg cgcacaccct cgctcgcggc cgccctccca cagccccaca      120

cactgggaga ccgcccaccg caaaccgcgg agacccccgt ctagatttaa agcgcggctg      180

cgcccggctt ctgacgtcca ttgaatcgcg cgggcggccg gcggcgagcg cggggctgcg      240

ccgggatcgc tgcgccctcc gccgctggcc tctgcgacgc gcgccgctcg cccgagccac      300

ccgccgccgc gccggctccc cgcgccgctg cgctcctcgc cccgcgcctg cccccaggat      360

ggtccgcgcg aggcaccagc cgggtgggct ttgcctcctg ctgctgctgc tctgccagtt      420

catggaggac cgcagtgccc aggctgggaa ctgctggctc cgtcaagcga agaacggccg      480

ctgccaggtc ctgtacaaga ccgaactgag caaggaggag tgctgcagca ccggccggct      540

gagcacctcg tggaccgagg aggacgtgaa tgacaacaca ctcttcaagt ggatgatttt      600

caacgggggc gcccccaact gcatcccctg taaagaaacg tgtgagaacg tggactgtgg      660

acctgggaaa aaatgccgaa tgaacaagaa gaacaaaccc cgctgcgtct gcgccccgga      720

ttgttccaac atcacctgga agggtccagt ctgcgggctg gatgggaaaa cctaccgcaa      780

tgaatgtgca ctcctaaagg caagatgtaa agagcagcca gaactggaag tccagtacca      840

aggcagatgt aaaaagactt gtcgggatgt tttctgtcca ggcagctcca catgtgtggt      900

ggaccagacc aataatgcct actgtgtgac ctgtaatcgg atttgcccag agcctgcttc      960

ctctgagcaa tatctctgtg ggaatgatgg agtcacctac tccagtgcct gccacctgag     1020

aaaggctacc tgcctgctgg gcagatctat tggattagcc tatgagggaa agtgtatcaa     1080

agcaaagtcc tgtgaagata tccagtgcac tggtgggaaa aaatgtttat gggatttcaa     1140

ggttgggaga ggccggtgtt ccctctgtga tgagctgtgc cctgacagta agtcggatga     1200

gcctgtctgt gccagtgaca atgccactta tgccagcgag tgtgccatga aggaagctgc     1260

ctgctcctca ggtgtgctac tggaagtaaa gcactccgga tcttgcaact ccatttcgga     1320

agacaccgag gaagaggagg aagatgaaga ccaggactac agctttccta tatcttctat     1380

tctagagtgg taaactctct ataagtgttc agtgttgaca tagcctttgt gcaaaaaaaa     1440

aaaaaaaaaa aaagaaaaag aaaaaaagaa aaatatattg tccatactgt aaataagtgt     1500

atgcttattt atttgggggg aaaactatac attaaaggac ctttgtccta aagctctctc     1560

ccaggccacc ttgttactca ttggacacgg agaggcattc attgtgaggt ctactggatg     1620

aggcccatag ttgagacttg tagacattta tttatactgt gtcatgtttt ataatttata     1680

cataaaatgt ctggttgact gtataccttg tttttgaaga aatttattcg tgaaaggaag     1740

agcagttgtt atttattgtg aggtctcttg cttgtaaagt aaaagctttt tttccttgta     1800

aaccatttaa gtccattcct tactattcac tcac                                 1834


<210>  2209
<211>  4835
<212>  DNA
<213>  homo sapiens

<400>  2209
gcctagggag gaggagcgag aatcagcctg gttcagtgac tgagacaaac tggaggtgaa       60

aggagctggt actgtccact gtgctgtcgg tgctgaacct gagacgcgag cggaccagtt      120

gctccagcac ctgaaggcaa cgccctcttg caccctctgt gccctgtggg acccgcttca      180

ccaacaggac ccatatcaac ttgacaaagg agtgtggtat cggacgtggg agagagtcct      240

ctgtttgcca cctgggcgct cattcaggcg tgactttgga gatttctata gttttagacc      300

aaactatttt tttttcccca gctaagacga tcttttgaga gttttttttt tttattgtga      360

tttatatttc cacagcgttt aggaatcttt ctgggggact tttgtgactg ttaaaataag      420

gtgaaaagca ataaggatgt ttaagtgctg gtcagttgtc ttggttctcg gattcatttt      480

tctggagtcg gaaggaaggc caaccaaaga aggaggatat ggccttaaat cctatcagcc      540

tctaatgaga ttgcgacata agcaggaaaa aaatcaagaa agttcaagag tcaaaggatt      600

tatgattcag gatggccctt ttggatcttg tgaaaataag tactgtggtt tgggaagaca      660

ctgtgttacc agcagagaga cagggcaagc agaatgtgcc tgtatggacc tttgcaaacg      720

tcactacaaa cctgtgtgtg gatctgacgg agaattctat gaaaaccact gtgaagtgca      780

cagagctgct tgcctgaaaa aacaaaagat taccattgtt cacaatgaag actgcttctt      840

taaaggagat aagtgcaaga ctactgaata cagcaagatg aaaaatatgc tattagattt      900

acaaaatcaa aaatatatta tgcaagaaaa tgaaaatcct aatggcgacg acatatctcg      960

gaagaagcta ttggtggatc aaatgtttaa atattttgat gcagacagta atggacttgt     1020

agatattaat gaactaactc aggtgataaa acaggaagaa cttggcaagg atctctttga     1080

ttgtactttg tatgttctat tgaaatatga tgattttaat gctgacaagc acctggctct     1140

tgaagaattt tatagagcat tccaagtgat ccagttgagt ctgccagaag atcagaaact     1200

aagcatcact gcagcaactg tgggacaaag tgctgttctg agctgtgcca ttcaaggaac     1260

cctgagacct cccattatct ggaaaaggaa caatattatt ctaaataatt tagatttgga     1320

agacatcaat gactttggag atgatgggtc cttgtatatt actaaggtta ccacaactca     1380

cgttggcaat tacacctgct atgcagatgg ctatgaacaa gtctatcaga ctcacatctt     1440

ccaagtgaat gttcctccag tcatccgggt gtatccagag agtcaggcta gagagcctgg     1500

ggtaactgcc agtcttaggt gccatgcaga gggcatacca aagcctcagc ttggctggtt     1560

gaagaatgga attgatatta caccaaagct ttccaaacaa ctcacgcttc aagcaaatgg     1620

cagtgaggtt cacataagca atgtgcgcta tgaagatact ggagcataca cttgtatcgc     1680

aaagaatgaa gcaggagtgg atgaagacat ctcttctctt tttgtggaag actctgctag     1740

aaagacccta gctaacatat tatggagaga agaaggtctg ggaattggga acatgttcta     1800

tgttttttat gaagatggaa tcaaagtgat acaacccata gaatgtgaat ttcagaggca     1860

cattaagcct agtgaaaagc tccttggatt tcaggatgaa gtctgtccca aagctgaggg     1920

agatgaagtt cagaggtgtg tgtgggcatc agctgttaat gtcaaagaca agttcattta     1980

tgttgcacag ccaactttgg acagagtcct tattgttgat gtgcagtccc aaaaagttgt     2040

tcaggcagtg agcacagacc ctgtcccagt taaattacac tatgacaaat cacatgatca     2100

ggtctgggtg ctaagctggg gtaccttgga gaagacatca ccaacactac aggtaattac     2160

cctggccagt gggaatgtgc ctcaccacac gatccacacc caaccagtgg gaaagcaatt     2220

tgacagagtg gatgattttt tcattcccac cacaacactc attatcaccc atatgaggtt     2280

tggatttatt cttcataaag atgaagctgc actacaaaaa attgatcttg aaaccatgtc     2340

atacatcaag acaattaact tgaaggacta taagtgcgtt cctcagtcat tggcatatac     2400

acacttggga ggctactact tcattggctg caaacctgac agcaccggag cagtttcccc     2460

acaggtcatg gtggacggtg taactgactc agtcattggg ttcaatagtg atgtgacggg     2520

cactccatat gtctctccag atggccacta ccttgtcagc attaatgatg tgaaaggtct     2580

tgtaagggtt cagtacatta ccatcagagg agaaatacag gaggcttttg atatttacac     2640

aaatctgcac atatctgatc tggcatttca accatccttt actgaagccc accaatataa     2700

catctacggt agttcaagca cacaaactga tgtgctcttt gtggagctct cttctgggaa     2760

ggtcaagatg ataaagagtc tcaaggaacc actcaaggca gaagaatggc cttggaaccg     2820

gaaaaacagg caaatccagg acagtggctt gtttggtcaa tacctgatga caccttccaa     2880

ggactctctc ttcatcctag atggacgact caataaatta aactgtgaga tcactgaagt     2940

tgaaaaagga aatacagtca tttgggttgg agatgcctaa aaaccctacg atacaattat     3000

tgaatgaagc gttttacaat acattgcact taatccattg tttaaattta caacttaact     3060

ttccaagttt atatcctagt caaacaaaat ttacttggtt ggtccaaata aaataaattg     3120

tttttgacta agtgactaag acatacacaa ttaattatat tggttaatta gaaatactca     3180

gcacaatatt taatgagaaa tcacatcagt cacaagaatc aaatatgtaa attatgcttt     3240

aaacaataaa gtaggattta aatcatttaa aaaactaaac tgcagggaat ttcagatgac     3300

ataaagcatt atttcatttt gagggtagtt tatttttttt ctctgtcctt ttggtatgat     3360

taaacaagaa ataaaaggtg ttgtggaaac ttaaaattct taattcaaaa tattcggtcc     3420

tgtccactgt ttataatatt ttgtgccttg aagggaatgt cacaggagga aaaggaagac     3480

taaagcctgc atactaaatg ctctcataac tataaatctc ttgttgttaa aaaacatctc     3540

ttgcaccaaa tcctgtcttc agtcttttgt ttaaccctca atgaactacc aattgaaggc     3600

ataagttggt cttaggttgt atacaggtgt caaactccac ttgacattta ctgtataatc     3660

tgcagcatgc tatagaaagt ggggaggaag ggaggaaaaa taattacagt caaaatattt     3720

gcaatctatc tactcatttt gctttcaatc actagagtgc attatgtttt taatgcaagt     3780

ttgtctggga tgtcaactgc ctacagatgt ttattactag cagaatagat tatttattaa     3840

tagattgttt cttttcatat agtccaatgt ttcatcatca ggaactttcg gttttaaaaa     3900

agaaacatta cttttgtctg ctaaagtaaa ccatatatag ggaaattaac acctaggaaa     3960

agaaaactgg caagagaatt gatgaggtat tagtggctta gaagaattag taatataagt     4020

tgggaataaa ggggtagccc gacagtggta agtaaaaatg tagtactcca ttgtttttgc     4080

tatttaaata taatgtatca aaaaccttta ttctaaaatt tccacaaatg attcctttta     4140

tccatcttct tgtaatccta aaagcatctt ctcactatgt gctgtagttt gaaacctaac     4200

gaatcctcct acttgagaca ctgtagaaaa gtaaaaattg ttgcttctgt tttgttttaa     4260

gaggaaatga gaaggccagc agaagtagat taaaactaga gagctggttt attaaaataa     4320

gcagataatt atccaggctt aaagtaatag cttacatgtt ttgaaaatcc ttgtacttat     4380

ttttgttttt attgttgcaa aaaaatgtta atgggctgtt gaaatgacct ccatttactt     4440

aaggtaatcc aataaggtct tttttaaata tacaaatttt actcaagttt aaattgtata     4500

aaactgctta gaaacctgaa attttatagt gtgtaatatc ttatgtgtat atagcatcct     4560

gagctgtgtg atacagtaga tttcttctta gcagaaacat gcgaggtaga tttaataaac     4620

aacaaaaatc agcttatgtt tctacttatt gaatctgctt tactttttag caattttctt     4680

ccttgtgaac atgaaccata taaagtgtct gtgacttaat gatttcatgt aagtctgtcg     4740

catacatcct tcttttgtag cttacaccat gtggatgctc tgtctgtaga cactgcttga     4800

taaaaggaga ataaacctct tacattttaa ccctt                                4835


<210>  2210
<211>  4832
<212>  DNA
<213>  homo sapiens

<400>  2210
gcctagggag gaggagcgag aatcagcctg gttcagtgac tgagacaaac tggaggtgaa       60

aggagctggt actgtccact gtgctgtcgg tgctgaacct gagacgcgag cggaccagtt      120

gctccagcac ctgaaggcaa cgccctcttg caccctctgt gccctgtggg acccgcttca      180

ccaacaggac ccatatcaac ttgacaaagg agtgtggtat cggacgtggg agagagtcct      240

ctgtttgcca cctgggcgct cattcaggcg tgactttgga gatttctata gttttagacc      300

aaactatttt tttttcccca gctaagacga tcttttgaga gttttttttt tttattgtga      360

tttatatttc cacagcgttt aggaatcttt ctgggggact tttgtgactg ttaaaataag      420

gtgaaaagca ataaggatgt ttaagtgctg gtcagttgtc ttggttctcg gattcatttt      480

tctggagtcg gaaggaaggc caaccaaaga aggaggatat ggccttaaat cctatcagcc      540

tctaatgaga ttgcgacata aggaaaaaaa tcaagaaagt tcaagagtca aaggatttat      600

gattcaggat ggcccttttg gatcttgtga aaataagtac tgtggtttgg gaagacactg      660

tgttaccagc agagagacag ggcaagcaga atgtgcctgt atggaccttt gcaaacgtca      720

ctacaaacct gtgtgtggat ctgacggaga attctatgaa aaccactgtg aagtgcacag      780

agctgcttgc ctgaaaaaac aaaagattac cattgttcac aatgaagact gcttctttaa      840

aggagataag tgcaagacta ctgaatacag caagatgaaa aatatgctat tagatttaca      900

aaatcaaaaa tatattatgc aagaaaatga aaatcctaat ggcgacgaca tatctcggaa      960

gaagctattg gtggatcaaa tgtttaaata ttttgatgca gacagtaatg gacttgtaga     1020

tattaatgaa ctaactcagg tgataaaaca ggaagaactt ggcaaggatc tctttgattg     1080

tactttgtat gttctattga aatatgatga ttttaatgct gacaagcacc tggctcttga     1140

agaattttat agagcattcc aagtgatcca gttgagtctg ccagaagatc agaaactaag     1200

catcactgca gcaactgtgg gacaaagtgc tgttctgagc tgtgccattc aaggaaccct     1260

gagacctccc attatctgga aaaggaacaa tattattcta aataatttag atttggaaga     1320

catcaatgac tttggagatg atgggtcctt gtatattact aaggttacca caactcacgt     1380

tggcaattac acctgctatg cagatggcta tgaacaagtc tatcagactc acatcttcca     1440

agtgaatgtt cctccagtca tccgggtgta tccagagagt caggctagag agcctggggt     1500

aactgccagt cttaggtgcc atgcagaggg cataccaaag cctcagcttg gctggttgaa     1560

gaatggaatt gatattacac caaagctttc caaacaactc acgcttcaag caaatggcag     1620

tgaggttcac ataagcaatg tgcgctatga agatactgga gcatacactt gtatcgcaaa     1680

gaatgaagca ggagtggatg aagacatctc ttctcttttt gtggaagact ctgctagaaa     1740

gaccctagct aacatattat ggagagaaga aggtctggga attgggaaca tgttctatgt     1800

tttttatgaa gatggaatca aagtgataca acccatagaa tgtgaatttc agaggcacat     1860

taagcctagt gaaaagctcc ttggatttca ggatgaagtc tgtcccaaag ctgagggaga     1920

tgaagttcag aggtgtgtgt gggcatcagc tgttaatgtc aaagacaagt tcatttatgt     1980

tgcacagcca actttggaca gagtccttat tgttgatgtg cagtcccaaa aagttgttca     2040

ggcagtgagc acagaccctg tcccagttaa attacactat gacaaatcac atgatcaggt     2100

ctgggtgcta agctggggta ccttggagaa gacatcacca acactacagg taattaccct     2160

ggccagtggg aatgtgcctc accacacgat ccacacccaa ccagtgggaa agcaatttga     2220

cagagtggat gattttttca ttcccaccac aacactcatt atcacccata tgaggtttgg     2280

atttattctt cataaagatg aagctgcact acaaaaaatt gatcttgaaa ccatgtcata     2340

catcaagaca attaacttga aggactataa gtgcgttcct cagtcattgg catatacaca     2400

cttgggaggc tactacttca ttggctgcaa acctgacagc accggagcag tttccccaca     2460

ggtcatggtg gacggtgtaa ctgactcagt cattgggttc aatagtgatg tgacgggcac     2520

tccatatgtc tctccagatg gccactacct tgtcagcatt aatgatgtga aaggtcttgt     2580

aagggttcag tacattacca tcagaggaga aatacaggag gcttttgata tttacacaaa     2640

tctgcacata tctgatctgg catttcaacc atcctttact gaagcccacc aatataacat     2700

ctacggtagt tcaagcacac aaactgatgt gctctttgtg gagctctctt ctgggaaggt     2760

caagatgata aagagtctca aggaaccact caaggcagaa gaatggcctt ggaaccggaa     2820

aaacaggcaa atccaggaca gtggcttgtt tggtcaatac ctgatgacac cttccaagga     2880

ctctctcttc atcctagatg gacgactcaa taaattaaac tgtgagatca ctgaagttga     2940

aaaaggaaat acagtcattt gggttggaga tgcctaaaaa ccctacgata caattattga     3000

atgaagcgtt ttacaataca ttgcacttaa tccattgttt aaatttacaa cttaactttc     3060

caagtttata tcctagtcaa acaaaattta cttggttggt ccaaataaaa taaattgttt     3120

ttgactaagt gactaagaca tacacaatta attatattgg ttaattagaa atactcagca     3180

caatatttaa tgagaaatca catcagtcac aagaatcaaa tatgtaaatt atgctttaaa     3240

caataaagta ggatttaaat catttaaaaa actaaactgc agggaatttc agatgacata     3300

aagcattatt tcattttgag ggtagtttat tttttttctc tgtccttttg gtatgattaa     3360

acaagaaata aaaggtgttg tggaaactta aaattcttaa ttcaaaatat tcggtcctgt     3420

ccactgttta taatattttg tgccttgaag ggaatgtcac aggaggaaaa ggaagactaa     3480

agcctgcata ctaaatgctc tcataactat aaatctcttg ttgttaaaaa acatctcttg     3540

caccaaatcc tgtcttcagt cttttgttta accctcaatg aactaccaat tgaaggcata     3600

agttggtctt aggttgtata caggtgtcaa actccacttg acatttactg tataatctgc     3660

agcatgctat agaaagtggg gaggaaggga ggaaaaataa ttacagtcaa aatatttgca     3720

atctatctac tcattttgct ttcaatcact agagtgcatt atgtttttaa tgcaagtttg     3780

tctgggatgt caactgccta cagatgttta ttactagcag aatagattat ttattaatag     3840

attgtttctt ttcatatagt ccaatgtttc atcatcagga actttcggtt ttaaaaaaga     3900

aacattactt ttgtctgcta aagtaaacca tatataggga aattaacacc taggaaaaga     3960

aaactggcaa gagaattgat gaggtattag tggcttagaa gaattagtaa tataagttgg     4020

gaataaaggg gtagcccgac agtggtaagt aaaaatgtag tactccattg tttttgctat     4080

ttaaatataa tgtatcaaaa acctttattc taaaatttcc acaaatgatt ccttttatcc     4140

atcttcttgt aatcctaaaa gcatcttctc actatgtgct gtagtttgaa acctaacgaa     4200

tcctcctact tgagacactg tagaaaagta aaaattgttg cttctgtttt gttttaagag     4260

gaaatgagaa ggccagcaga agtagattaa aactagagag ctggtttatt aaaataagca     4320

gataattatc caggcttaaa gtaatagctt acatgttttg aaaatccttg tacttatttt     4380

tgtttttatt gttgcaaaaa aatgttaatg ggctgttgaa atgacctcca tttacttaag     4440

gtaatccaat aaggtctttt ttaaatatac aaattttact caagtttaaa ttgtataaaa     4500

ctgcttagaa acctgaaatt ttatagtgtg taatatctta tgtgtatata gcatcctgag     4560

ctgtgtgata cagtagattt cttcttagca gaaacatgcg aggtagattt aataaacaac     4620

aaaaatcagc ttatgtttct acttattgaa tctgctttac tttttagcaa ttttcttcct     4680

tgtgaacatg aaccatataa agtgtctgtg acttaatgat ttcatgtaag tctgtcgcat     4740

acatccttct tttgtagctt acaccatgtg gatgctctgt ctgtagacac tgcttgataa     4800

aaggagaata aacctcttac attttaaccc tt                                   4832


<210>  2211
<211>  4356
<212>  DNA
<213>  homo sapiens

<400>  2211
aagcagatag gtttcagaga taaagagtga aaccaaaaac accgcacacc tcatccaaat       60

ctgcgctcat acttgcagca aatgtttgct gtcagttgct tcataataac agcacagacc      120

ccgaattgca ggaggaattg cctggtagaa aactgaagac tttaataaca aactctccaa      180

ggtgaaaatg aacacagggc gtgattctca gtcaccagac tcagcttgga gatcttacaa      240

tgatggcaat caggagacac tgaacggaga tgctacatat tcctctcttg cagcaaaagg      300

ttttagaagc gttcgaccaa acctacaaga taaaagatca ccaactcaga gccagataac      360

agtgaatgga aactcaggag gtgccgtgag tcccatgagt tactatcaga ggccgttttc      420

cccctcggca tattctctcc cagcctcact caactccagc attgtcatgc agcacggcac      480

atccctcgat tccacagaca catatcccca gcatgcgcag tctctggatg gcaccaccag      540

cagctctatc cccctgtacc gatcctcaga ggaagagaag agagtgacag tcatcaaagc      600

cccgcattac ccagggatcg ggcccgtgga tgaatccgga atccccacag caattagaac      660

gacagtcgac cggcccaagg actggtacaa gacgatgttt aagcaaattc acatggtgca      720

caagccggat gatgacacag acatgtataa tactccttat acatacaatg caggtctgta      780

caacccaccc tacagtgctc agtcacaccc tgctgcaaag acccaaacct acagacctct      840

ttccaaaagc cactccgaca acagccccaa tgcctttaag gatgcgtcct ccccagtgcc      900

tcccccacat gttccacctc cagtcccgcc gcttcgacca agagatcggt cttcaacaga      960

aaagcatgac tgggatcctc cagacagaaa agtggacaca agaaaatttc ggtctgagcc     1020

aaggagtatt tttgaatatg aacctggcaa gtcatcaatt cttcagcatg aaagaccacc     1080

tcctaaaaag cctctggact atgttcaaga tcattcttct ggtgttttca atgaggcctc     1140

cttgtatcag tcctctatag acagaagcct ggaaagaccc atgagttctg caagcatggc     1200

cagtgacttc aggaagcgga ggaagagcga gcctgcagtg ggtccaccac ggggcttggg     1260

agatcaaagt gcgagcagga ctagcccagg ccgagtggac ctcccaggat caagcaccac     1320

tcttacaaag tctttcacta gctcttctcc ttcttcccca tcaagagcaa aagaccgtga     1380

gtcccctaga agttactcat ccactttgac tgacatgggg agaagtgcac caagggaaag     1440

aagaggaact ccagaaaaag agaaattgcc tgcaaaagct gtttatgatt ttaaggctca     1500

gacatctaag gagttgtcat ttaagaaagg agatactgtc tacatcctca ggaaaattga     1560

tcaaaattgg tatgagggag aacaccacgg gagagtgggc atcttcccga tctcatacgt     1620

agagaaactc acacctcctg agaaagcaca gcctgcaaga ccacctccgc cagcccagcc     1680

cggagaaatc ggagaagcta tagccaaata caacttcaac gcagacacaa atgtggagct     1740

gtcactgaga aagggagata gagttattct tcttaaaaga gttgatcaaa actggtatga     1800

aggtaaaatc ccaggaacca acagacaagg catcttccct gtttcctatg tggaggtcgt     1860

caagaagaac acaaaaggtg ctgaggacta ccctgaccct ccaatacccc acagctattc     1920

tagtgatagg attcacagct tgagctcaaa taagccacag cgtcctgtgt ttactcatga     1980

aaatattcaa ggtggggggg aaccgtttca ggctctgtat aactatactc ccaggaatga     2040

agatgagctg gagctcagag aaagtgatgt cattgatgtc atggaaaagt gtgatgacgg     2100

ctggtttgtg gggacctcaa gaagaaccaa attctttggt actttccccg gaaactacgt     2160

caagaggctg tgaattgcgc tccctccttc tgtagaggcc gcctgccagc catgcacctg     2220

cgtcaacgcg cctgaaacac cccgcgggcc tcccgttgtc atgccttacg gtttccaatg     2280

cgccgtcacc atctccacct gccaccaaac caccagcaga gtagccgccg ctgctgtgag     2340

cctggggacg acatggcagg ctggtccccc tccgtgaaag tgtggattcc tacttcctgc     2400

tctaagcttt gacacgtcaa aatgtgggat cagaaagaaa aaaatcatga tatttaaaaa     2460

tggtcaaata tttgaggcaa aaaaaaaaaa aaaaagtgtc tccaggaggc tgtccagcct     2520

cgtggctcca tttcaacatc tccccccagg cgatgttctc ccccaagacg accagaaaat     2580

tgtttattgg ggaatgctgt ggtttgcatt ttcatattct tcgcttggca gtgtgtattc     2640

ttttcacaag tttgcctagt gtcttggttt acacaatatg acaactgtaa ctgtacttta     2700

gctattgttt gcctgcacat acatgttgta atatgcacag tgattacaac ctttaaagca     2760

agaggaggcg agttaatttg gatgagtgtg attttgctga ttgaatgtga gttttcaaat     2820

aggagtcttt ttctgcaatt tgtttgcatt ttttagaagt gcaaacagta agtaaataaa     2880

agccttcggt aataatcatg acaatacaag aggctgagct aggctacagg ggaaaactat     2940

tgtgttgtaa agttgcatcg ctattttata ttaaaatgta atgatcagca tcatgaacaa     3000

tgagctctta gtgttttatt tatctgaaaa aatgtaagta aaagcagtgt tagtgagagg     3060

tgcaaagaat tattctaaca gacacctgaa agtatctgta agcaatacta gtaggtaaga     3120

tttcactgtg tgtacacata cacatttgag attgtatgag aacatataat ccatatgata     3180

tgttgtacat tttatggaaa tgtaatagaa tctcacacat tattttatag aaatagagta     3240

cagaagcatc acaagtatta aagttggttt tagcaaggat taggattact acaattattt     3300

ttactataat aattattttt cttctatgga actcagaatc ctggctacat ttgaggacag     3360

gaatatgttg agcctgattt tcctggtgtg tgtaaaatat ttcctaggaa taaattaggc     3420

actttttaga agcaatgtta aatcattcag gttttatttt ctgccctgaa gcagaaattt     3480

aaaaaatgat attgggacct ggaaggttta atatggttca cagtgcctga attacacctg     3540

ctccgaaaac tagctttgta tttcttatga ctttgcataa gaactgttca tctttggatc     3600

ttgagcacct tacagataaa actttttatg gcatctcttt catggacagt gatattgatc     3660

ttttcacaat gtacgtagcc tctagaattt tgtacatatg tttgctcttt ttttgtacag     3720

actagttgtt gagaaaacag gggcgtttcc taatttggtc tttatcctgc gacaacactt     3780

tcagcagact agcctctcct tatctcacag atcacaagca cccctagata gtgtgattct     3840

gtcagatagc atttatgcaa aaatctatga agttaaaaga tcgtagaagc caaatgaaat     3900

gtacatatct actgactgat gacaagggaa tttcattagg aagaaggtaa agaaacatcg     3960

ttgagtagcc taccttgatt tctgtcaagt tcataaccag cttcatattt taaaggcttc     4020

aggtttgaaa ttaagtcaac tgcatgcagc tttgctgata aatgaataat tctctttgat     4080

gccatttatg agaaaagact tcaatatctg ttgcctgtca tatttaagaa aaattactgt     4140

ttctactctc tgtatctgat tttaaaagaa aaaactattc atacctggct tccaggtaat     4200

tgactttgaa ttcttacaag caaaggtcat tgtgtttttc ttgaatagac atctaataaa     4260

ttttgcttgg aagtatactt cagtttttct tcttgacatt tatctttata aaaattgtgt     4320

attttattcc aacttgttaa actaagagaa aatgca                               4356


<210>  2212
<211>  3149
<212>  DNA
<213>  homo sapiens

<400>  2212
ctgagctcag ggaggagctc cctccaggct ctatttagag ccgggtaggg gagcgcagcg       60

gccagatacc tcagcgctac ctggcggaac tggatttctc tcccgcctgc cggcctgcct      120

gccacagccg gactccgcca ctccggtagc ctcatggctg caacctgtga gattagcaac      180

atttttagca actacttcag tgcgatgtac agctcggagg actccaccct ggcctctgtt      240

ccccctgctg ccacctttgg ggccgatgac ttggtactga ccctgagcaa cccccagatg      300

tcattggagg gtacagagaa ggccagctgg ttgggggaac agccccagtt ctggtcgaag      360

acgcaggttc tggactggat cagctaccaa gtggagaaga acaagtacga cgcaagcgcc      420

attgacttct cacgatgtga catggatggc gccaccctct gcaattgtgc ccttgaggag      480

ctgcgtctgg tctttgggcc tctgggggac caactccatg cccagctgcg agacctcact      540

tccagctctt ctgatgagct cagttggatc attgagctgc tggagaagga tggcatggcc      600

ttccaggagg ccctagaccc agggcccttt gaccagggca gcccctttgc ccaggagctg      660

ctggacgacg gtcagcaagc cagcccctac caccccggca gctgtggcgc aggagccccc      720

tcccctggca gctctgacgt ctccaccgca gggactggtg cttctcggag ctcccactcc      780

tcagactccg gtggaagtga cgtggacctg gatcccactg atggcaagct cttccccagc      840

gatggttttc gtgactgcaa gaagggggat cccaagcacg ggaagcggaa acgaggccgg      900

ccccgaaagc tgagcaaaga gtactgggac tgtctcgagg gcaagaagag caagcacgcg      960

cccagaggca cccacctgtg ggagttcatc cgggacatcc tcatccaccc ggagctcaac     1020

gagggcctca tgaagtggga gaatcggcat gaaggcgtct tcaagttcct gcgctccgag     1080

gctgtggccc aactatgggg ccaaaagaaa aagaacagca acatgaccta cgagaagctg     1140

agccgggcca tgaggtacta ctacaaacgg gagatcctgg aacgggtgga tggccggcga     1200

ctcgtctaca agtttggcaa aaactcaagc ggctggaagg aggaagaggt tctccagagt     1260

cggaactgag ggttggaact atacccggga ccaaactcac ggaccactcg aggcctgcaa     1320

accttcctgg gaggacaggc aggccagatg gcccctccac tggggaatgc tcccagctgt     1380

gctgtggaga gaagctgatg ttttggtgta ttgtcagcca tcgtcctggg actcggagac     1440

tatggcctcg cctccccacc ctcctcttgg aattacaagc cctggggttt gaagctgact     1500

ttatagctgc aagtgtatct ccttttatct ggtgcctcct caaacccagt ctcagacact     1560

aaatgcagac aacaccttcc tcctgcagac acctggactg agccaaggag gcctggggag     1620

gccctagggg agcaccgtga tggagaggac agagcagggg ctccagcacc ttctttctgg     1680

actggcgttc acctccctgc tcagtgcttg ggctccacgg gcaggggtca gagcactccc     1740

taatttatgt gctatataaa tatgtcagat gtacatagag atctattttt tctaaaacat     1800

tcccctcccc actcctctcc cacagagtgc tggactgttc caggccctcc agtgggctga     1860

tgctgggacc cttaggatgg ggctcccagc tcctttctcc tgtgaatgga ggcagagacc     1920

tccaataaag tgccttctgg gctttttcta acctttgtct tagctacctg tgtactgaaa     1980

tttgggcctt tggatcgaat atggtcaaga ggttggaggg gaggaaaatg aaggtctacc     2040

aggctgaggg tgagggcaaa ggctgacgaa gaggggagtt acagatttcc tgtagcaggt     2100

gtgggcttac agacacatgg actgggctgg gaggcgagca aaggaagcag ctgagactgt     2160

tggagaacgc ttacaagact tcatgcaagc aaggacatga actcagaaca ctgaggtcag     2220

aagcatcctg ctgtcatgac accgctcgag tgaccttgac cttgaccaag tctgtcctgt     2280

ttaggactga tttttcctat taggctaggg tttggacctg atgttctcaa gatgtctaga     2340

attgcatggc tggccttgtg gaatagatgg ttttgcattc cagccaagtg tgctgtaaac     2400

tgtatatctg taatatgaat cccagctttt gagtctgaca aaatcagagt taggatcttg     2460

taaaggaaaa aaaaaaaaaa acaaaacaaa atggagatga gtacttgctg agaaagaatg     2520

agggaaggag ttggcatttg ttgaaagtgt agtctttttc tctttttttt ttaattgcaa     2580

cttttacttt agatttagga ggtcgtgcgc aggtttgtta catgggtata ttgtgtgatg     2640

ctgagcttgg gatgcgaatg atcctgtcac ccaggtagtg agtatagcac ccagtgaaac     2700

tgtagtctca tgccaggcac tgtgctagcc cactctggct catttaatcc tctcctaaga     2760

agagaggaga cacagcgtcc ccatttgaca gatgcagaaa gaggttccac aggtgtgcct     2820

tgattctgtc ctaaaaccgt ttcccggaag cttttcctgg tgtgggcgct tctaacctaa     2880

tcctcaatcg attccagaac tattactctg tttccacagt gatactgtgt ctaggtttta     2940

gggaggacag ttcattgatg ttacttaaga atgctttcca ggtggaaagt tccttaagtt     3000

tgaggcttca aattccatac agcacattaa aatcccattc atgagtttga aatactgctc     3060

tgttgtcttg gaaataccaa tcagattgtt ggctgaagtg atgtggataa agaagggatc     3120

ttagaaaaac taaaaaaaaa aaaaaaaaa                                       3149


<210>  2213
<211>  2934
<212>  DNA
<213>  homo sapiens

<400>  2213
ctcgggccca cgtgagctgt agggaaacgc aggggcggct tctaggtgct gccgccgcca       60

ccgccaccac cacctccacc gccgcctcgg aacccaggcc tggggggcgg tggggccgcg      120

tatggagccc ccgccccccg gagctgccaa cattgccaac gccaccgcca cgctacacac      180

agcctcaact ttcaggagac ccgtccgtgg ccttatttat tccacccttc ctgtacatcg      240

tagcgaatca atccgtggcg ccgcactcct ccgcatccct ctttaacagt acccctggga      300

tggcgtgagc actcccccag cgatggaccc atctgtgacg ctgtggcagt ttctgctgca      360

gctgctgaga gagcaaggca atggccacat catctcctgg acttcacggg atggtggtga      420

attcaagctg gtggatgcag aggaggtggc ccggctgtgg gggctacgca agaacaagac      480

caacatgaat tacgacaagc tcagccgggc cttgcggtac tactatgaca agaacatcat      540

ccgcaaggtg agcggccaga agttcgtcta caagtttgtg tcctaccctg aggtcgcagg      600

gtgctccact gaggactgcc cgccccagcc agaggtgtct gttacctcca ccatgccaaa      660

tgtggcccct gctgctatac atgccgcccc aggggacact gtctctggaa agccaggcac      720

acccaagggt gcaggaatgg caggcccagg cggtttggca cgcagcagcc ggaacgagta      780

catgcgctcg ggcctctatt ccaccttcac catccagtct ctgcagccgc agccaccccc      840

tcatcctcgg cctgctgtgg tgctccccag tgcagctcct gcaggggcag cagcgccccc      900

ctcggggagc aggagcacca gtccaagccc cttggaggcc tgtctggagg ctgaagaggc      960

cggcttgcct ctgcaggtca tcctgacccc gcccgaggcc ccaaacctga aatcggaaga     1020

gcttaatgtg gagccgggtt tgggccgggc tttgccccca gaagtgaaag tagaagggcc     1080

caaggaagag ttggaagttg cgggggagag agggtttgtg ccagaaacca ccaaggccga     1140

gccagaagtc cctccacagg agggcgtgcc agcccggctg cccgcggttg ttatggacac     1200

cgcagggcag gcgggcggcc atgcggcttc cagccctgag atctcccagc cgcagaaggg     1260

ccggaagccc cgggacctag agcttccact cagcccgagc ctgctaggtg ggccgggacc     1320

cgaacggacc ccaggatcgg gaagtggctc cggcctccag gctccggggc cggcgctgac     1380

cccatccctg cttcctacgc atacattgac cccggtgctg ctgacaccca gctcgctgcc     1440

tcctagcatt cacttctgga gcaccctgag tcccattgcg ccccgtagcc cggccaagct     1500

ctccttccag tttccatcca gtggcagcgc ccaggtgcac atcccttcta tcagcgtgga     1560

tggcctctcg acccccgtgg tgctctcccc agggccccag aagccatgac tactaccacc     1620

accaccacca ccccttctgg ggtcactcca tccatgctct ctccagccag ccatctcaag     1680

gagaaacata gttcaactga aagactcatg ctctgattgt ggtggggtgg ggatccttgg     1740

gaagaattac tcccaagagt aactctcatt atctcctcca cagaaaacac acagcttcca     1800

caacttctct gttttctgtc agtcccccag tggccgccct tacacgtctc ctacttcaat     1860

ggtaggggcg gtttatttat ttattttttg aaggccactg ggaggagcct gacctaacct     1920

tttagggtgg ttaggacatc tcccccacct ccccactttt ttccccaaga caagacaatc     1980

gaggtctggc ttgagaacga cctttctttc tttatttctc agcctgccct tggggagatg     2040

agggagccct gtctgcgttt ttggatgtga gtagaagagt tagtttgttt tgttttatta     2100

ttcctggcca tactcagggg tccaggaaga atttgtacca tttaatgggt tgggagtctt     2160

ggccaaggaa gaatcacacc cttggaatag aaatttccac ctccccaacc tttctctcag     2220

acagcttatc cttttcaacc aactttttgg ccagggagga atgtcccttt tgttcttccc     2280

cctgagaagc cattcctttg tctgccaacc tccctggggt cctgcctgtt tcctcccaat     2340

ggagggtttt tttggggggt ggtccccgtc tggggggccc ctccagccag tactccaggt     2400

ctccctgtct ctcccccgct gccattttga tagtataatc tatttttaaa tggggctttt     2460

caatagggga gagggagtca tctcttccta tatttggtgg ggtgggtggg aaggaaggga     2520

tttggggggg aatcttcctg ccgcctcccc cactccaagt gtttattttt gataccaaac     2580

atgaattttc agttccctcc ctcccagccc cccaatttcc tgcgggcggg tacaaaggac     2640

cctttcaatg tccctggagt tgggagggag gaatggggga cataaagcct gtcctgtctc     2700

tattctaggc aagagagagt gggttcaaaa gactcctggg ctcacctgtt agcgctggcc     2760

cagcccaggc cttgggacct gggggttggt gatttggggg acagtgctac actcgtctcc     2820

actgtttgtt ttacttcccc aaaatggacc tttttttttt ctaaagagtc ccagagaatg     2880

gggaattgtt cctgtaaata tatatttttc aaagtgataa aaaaaaaaaa aaaa           2934


<210>  2214
<211>  2828
<212>  DNA
<213>  homo sapiens

<400>  2214
ctcgggccca cgtgagctgt agggaaacgc aggggcggct tctaggtgct gccgccgcca       60

ccgccaccac cacctccacc gccgcctcgg aacccaggcc tggggggcgg tggggccgcg      120

tatggagccc ccgccccccg gagctgccaa cattgccaac gccaccgcca cgctacacac      180

aggtacccct gggatggcgt gagcactccc ccagcgatgg acccatctgt gacgctgtgg      240

cagtttctgc tgcagctgct gagagagcaa ggcaatggcc acatcatctc ctggacttca      300

cgggatggtg gtgaattcaa gctggtggat gcagaggagg tggcccggct gtgggggcta      360

cgcaagaaca agaccaacat gaattacgac aagctcagcc gggccttgcg gtactactat      420

gacaagaaca tcatccgcaa ggtgagcggc cagaagttcg tctacaagtt tgtgtcctac      480

cctgaggtcg cagggtgctc cactgaggac tgcccgcccc agccagaggt gtctgttacc      540

tccaccatgc caaatgtggc ccctgctgct atacatgccg ccccagggga cactgtctct      600

ggaaagccag gcacacccaa gggtgcagga atggcaggcc caggcggttt ggcacgcagc      660

agccggaacg agtacatgcg ctcgggcctc tattccacct tcaccatcca gtctctgcag      720

ccgcagccac cccctcatcc tcggcctgct gtggtgctcc ccagtgcagc tcctgcaggg      780

gcagcagcgc ccccctcggg gagcaggagc accagtccaa gccccttgga ggcctgtctg      840

gaggctgaag aggccggctt gcctctgcag gtcatcctga ccccgcccga ggccccaaac      900

ctgaaatcgg aagagcttaa tgtggagccg ggtttgggcc gggctttgcc cccagaagtg      960

aaagtagaag ggcccaagga agagttggaa gttgcggggg agagagggtt tgtgccagaa     1020

accaccaagg ccgagccaga agtccctcca caggagggcg tgccagcccg gctgcccgcg     1080

gttgttatgg acaccgcagg gcaggcgggc ggccatgcgg cttccagccc tgagatctcc     1140

cagccgcaga agggccggaa gccccgggac ctagagcttc cactcagccc gagcctgcta     1200

ggtgggccgg gacccgaacg gaccccagga tcgggaagtg gctccggcct ccaggctccg     1260

gggccggcgc tgaccccatc cctgcttcct acgcatacat tgaccccggt gctgctgaca     1320

cccagctcgc tgcctcctag cattcacttc tggagcaccc tgagtcccat tgcgccccgt     1380

agcccggcca agctctcctt ccagtttcca tccagtggca gcgcccaggt gcacatccct     1440

tctatcagcg tggatggcct ctcgaccccc gtggtgctct ccccagggcc ccagaagcca     1500

tgactactac caccaccacc accacccctt ctggggtcac tccatccatg ctctctccag     1560

ccagccatct caaggagaaa catagttcaa ctgaaagact catgctctga ttgtggtggg     1620

gtggggatcc ttgggaagaa ttactcccaa gagtaactct cattatctcc tccacagaaa     1680

acacacagct tccacaactt ctctgttttc tgtcagtccc ccagtggccg cccttacacg     1740

tctcctactt caatggtagg ggcggtttat ttatttattt tttgaaggcc actgggagga     1800

gcctgaccta accttttagg gtggttagga catctccccc acctccccac ttttttcccc     1860

aagacaagac aatcgaggtc tggcttgaga acgacctttc tttctttatt tctcagcctg     1920

cccttgggga gatgagggag ccctgtctgc gtttttggat gtgagtagaa gagttagttt     1980

gttttgtttt attattcctg gccatactca ggggtccagg aagaatttgt accatttaat     2040

gggttgggag tcttggccaa ggaagaatca cacccttgga atagaaattt ccacctcccc     2100

aacctttctc tcagacagct tatccttttc aaccaacttt ttggccaggg aggaatgtcc     2160

cttttgttct tccccctgag aagccattcc tttgtctgcc aacctccctg gggtcctgcc     2220

tgtttcctcc caatggaggg tttttttggg gggtggtccc cgtctggggg gcccctccag     2280

ccagtactcc aggtctccct gtctctcccc cgctgccatt ttgatagtat aatctatttt     2340

taaatggggc ttttcaatag gggagaggga gtcatctctt cctatatttg gtggggtggg     2400

tgggaaggaa gggatttggg ggggaatctt cctgccgcct cccccactcc aagtgtttat     2460

ttttgatacc aaacatgaat tttcagttcc ctccctccca gccccccaat ttcctgcggg     2520

cgggtacaaa ggaccctttc aatgtccctg gagttgggag ggaggaatgg gggacataaa     2580

gcctgtcctg tctctattct aggcaagaga gagtgggttc aaaagactcc tgggctcacc     2640

tgttagcgct ggcccagccc aggccttggg acctgggggt tggtgatttg ggggacagtg     2700

ctacactcgt ctccactgtt tgttttactt ccccaaaatg gacctttttt ttttctaaag     2760

agtcccagag aatggggaat tgttcctgta aatatatatt tttcaaagtg ataaaaaaaa     2820

aaaaaaaa                                                              2828


<210>  2215
<211>  2310
<212>  DNA
<213>  homo sapiens

<400>  2215
gtaatttgcc tggcaagtga tcagactggt ataaaataac atcatctgtt aggcaagata       60

gcagtcacaa agaactattg gtcttttaaa atatagaatt tttaatgaga aactttgaat      120

aatagagatt gaacatgtga gaacagctac ctagtgtgtg ttgcattatt aacccctagt      180

ttgtagtgta ttctggagtc aagttgacct acatagaaga gaaggaactg gaagtgcatg      240

tctgtgttct ggctccgatt gggaaaagct gcttaaccac tgttacactt ccaggggctc      300

cccactcagt ccccagtcat ctatcgacag tgagctgagt acttcagaat tggaggatga      360

ttctatctcc atgggatata aattacagga cctcactgat gttcagatca tggctcgtct      420

gcaagaagaa agtctcaggc aagattatgc ttctacttca gcatctgtat caagacatag      480

ttccagtgtg tcattgagtt caggaaaaaa agggacatgt agtgatcaag aatatgacca      540

atacagtctg gaggatgaag aggaatttga tcatttgcca ccacctcagc ctcgtcttcc      600

aagatgttcc cctttccaaa gaggaattcc ccattcacag actttctcca gcattcggga      660

gtgtaggagg agccccagtt cccagtattt tccttcaaat aattaccagc agcaacagta      720

ttattcacct caagcccaaa ctccagatca gcaaccaaat aggaccaatg gagataagct      780

ccgaagaagt atgcctaacc tagcccggat gccaagtaca actgccatta gtagcaacat      840

tagttctccg gtcaccgtgc gaaatagtca gagttttgac tcaagcttgc atggagctgg      900

aaatggaatt tcaagaatac aatcttgtat tccatcaccg ggacagcttc aacacagggt      960

ccacagcgtg gggcatttcc cagtgtctat ccgacagcct cttaaagcca cagcctatgt     1020

gagtccaacc gttcaaggca gcagtaacat gcctttatca aacggcttac agctgtattc     1080

caacacagga atccccacac cgaacaaagc tgcagcttct gggataatgg gtcgcagtgc     1140

actcccaaga ccttcgttgg caataaatgg gagtaacctg cctcgaagca aaattgcaca     1200

acctgttaga agttttcttc agcctccaaa gcctctgtct tcactcagca ctctgaggga     1260

tggaaattgg agagatggtt gctactaatg cagttttatg tacccttgaa aaatgggaaa     1320

gaagtaaaaa tgagggttgt gttacctagc tggctgggta gcagtggatg ttgggatatt     1380

ctttcccttt tgtgttttaa tatatttact gcattgtttc tcaatggacc agtcaccaga     1440

gactaattat tgcacttaaa tatttgcctg agatactgca acattctcaa acccatggtt     1500

gcagtattgt gacacttaga tctaggaagt ttttgtagaa ctgctctgta cctgaatact     1560

ttttgagaga attaagatgt atcaataatg ctttgccata tgagtttttt aaagtaactt     1620

gttcaattta ctcacgtgtt ctaaacatct ttccattaca tgttctgtat tttaatacat     1680

tgcatattga caactaggtt ctataatgta tgctttgaaa tttacttttt tatagtttac     1740

aggaatttta ttttttgtgc ctatttcttt ttacacctat gtgaaccact atggaacaac     1800

ttaaattttg tgccataaaa atatttttgt ggtaaggtac tattttttta gctctaggga     1860

tatatcagca aaaacacatc atgcaatttg agacacataa ttttgtgttg aatgagcaca     1920

acataatttg aagcattgca aggagataac cagacagcag aattaaatgg tcctgtcttt     1980

ttcattttta atttattgtc atacatgggt ttcatattta taacggcatc atgagctcat     2040

tgcacttaat acctgcaatg tttgctactg taccacaatt gattttcaat actttattac     2100

gaaggatgaa actgtaatgt tttattaaca atgcttctgg aaatgaatgc attttaaagc     2160

aaataaatct ttttgataga ccttttacaa aatccatttg cactaatgaa tgctttctta     2220

tggcatataa cttaatattt gttactgtgt acactgctgt tttggaatgt tcagaaataa     2280

agactctatt tcagcaatat caggtcatgc                                      2310


<210>  2216
<211>  8106
<212>  DNA
<213>  homo sapiens

<400>  2216
agaaagtagc agaaagtgag gctggcaggc ggcggcaaag gagccggcgc gcggcggcgg       60

caggaagtct gtgcccgaga acagcagaaa taagagccag ggagggaccg cggccgcggc      120

ggcggcggcg agagcgaaag aggaaactgc agaggaggaa gctgcgccgc agcccgagcc      180

gcccggcatc cccgccgcct ctgcgcccgc gccgcgcccc cggcgccccc tccccagcgc      240

gcccccggcc gctcctccgc gccgcgctcg tcggccatgg cccgggagaa cggcgagagc      300

agctcctcct ggaaaaagca agctgaagac atcaagaaga tcttcgagtt caaagagacc      360

ctcggaaccg gggccttttc cgaagtggtt ttagctgaag agaaggcaac tggcaagctc      420

tttgctgtga agtgtatccc taagaaggcg ctgaagggca aggaaagcag catagagaat      480

gagatagccg tcctgagaaa gattaagcat gaaaatattg ttgccctgga agacatttat      540

gaaagcccaa atcacctgta cttggtcatg cagctggtgt ccggtggaga gctgtttgac      600

cggatagtgg agaaggggtt ttatacagag aaggatgcca gcactctgat ccgccaagtc      660

ttggacgccg tgtactatct ccacagaatg ggcatcgtcc acagagacct caagcccgaa      720

aatctcttgt actacagtca agatgaggag tccaaaataa tgatcagtga ctttggattg      780

tcaaaaatgg agggcaaagg agatgtgatg tccactgcct gtggaactcc aggctatgtc      840

gctcctgaag tcctcgccca gaaaccttac agcaaagccg ttgactgctg gtccatcgga      900

gtgattgcct acatcttgct ctgcggctac cctccttttt atgatgaaaa tgactccaag      960

ctctttgagc agatcctcaa ggcggaatat gagtttgact ctccctactg ggatgacatc     1020

tccgactctg caaaagactt cattcggaac ctgatggaga aggacccgaa taaaagatac     1080

acgtgtgagc aggcagctcg gcacccatgg atcgctggtg acacagccct caacaaaaac     1140

atccacgagt ccgtcagcgc ccagatccgg aaaaactttg ccaagagcaa atggagacaa     1200

gcatttaatg ccacggccgt cgtcagacat atgagaaaac tacacctcgg cagcagcctg     1260

gacagttcaa atgcaagtgt ttcgagcagc ctcagtttgg ccagccaaaa agactgtctg     1320

gcaccttcca cgctctgtag tttcatttct tcttcgtcgg gggtctcagg agttggagcc     1380

gagcggagac ccaggcccac cactgtgacg gcagtgcact ctggaagcaa gtgactggcc     1440

ctggaggtgg ggcccggggt cggggctggg gaaggggagc cccagggtcg ccagagccgc     1500

gagccactcc agcgagaccc caccttgcat ggtgcccctt cctgcatagg actggaagac     1560

cgaagttttt ttatggccat attttctact gcaattctga agtgttcatt tctcacaaac     1620

tgtactgact cgaggggcgc tgatttcata ggatctggtg ctgtatatac gaatcttgca     1680

aagctctaac tgaacggacc ttcttattcc tctcccctaa caccatcgtt tccactcttc     1740

tcagtgtagg taaccgtcta tggtgtgttt tttcattaat gacaaaaaaa aaaaggtttc     1800

aactggatta tttaaatatt ggtaaatatt gtgcattagg gtttgttttt ccttttaaga     1860

agtatgtcct ttgtatctct aagttacatg acctatatct tttcctcttt aatagtagtt     1920

ttatgttaac ctttaagaga tttgtttttc ctcaaaggag aatttaaagg tattttttaa     1980

aattctaata agaggatcag ccgggtgcaa tgactcatgc ctgtaatccc agcacgttgg     2040

gaggccaagt cgggcggatc acaaggtcag gagatcaagg ccatcctggc caacatggtg     2100

aaaccccacg tctactaaaa atacaaaaaa ttagccgggc gtggtggcac acacctgtag     2160

tcccggctac tcgggaggct gaggcaggag aattgcttga acccgggaga cggaggttgc     2220

agtgagctga gatcgtgcca ctgcactcca gcctgggtga cagagcaaga ctctgtctca     2280

aaaaaaaaaa aaaaaattct aacaagagga tcatgaatct gtctccaagg ctaagagtgc     2340

ccttcacctc tactccttct gtttctctcc ccttccccag gaggaggggc ccctcagttc     2400

tgcgaggctc tcttctctgc gggggacttt ggtagagaat ctgcacagag cctttgctgg     2460

caacccatcc agcagaaccc acacccacca gagaccctag aggcctcttg ccatcagcaa     2520

ccagaaataa gcctgctccc ccgagacgca gggctcagct tcacaggcca gacttgctgt     2580

gagtgagatg cccacactgc agagatgcag gaccctccct tgcaaaagga accagctgcc     2640

atgttgctga aagtgggccc acacacaacc ctcatttctc acgagagcta acagatgaaa     2700

gctcagctat gcagtgttaa aattcatctc tttctctgtg gtttttaaaa aaatgcattt     2760

ctaatcttac acttcacgtg gcctccaaca caaagttctt tctccacatt tttaccctct     2820

tctcacatga atgttttcca agggaaggaa gggagggaag cagccttggg aaaggatcca     2880

tttctggtgg taaggagagg gggccctgcc aggctaatgg gacttcagcc accacagaga     2940

tgaccaaaga ccacctccgc caggcccagc cagtgcttgc agccctccca ttggtcaggg     3000

gagtctaaaa tcaaagatac atggtggtag ggtcaccaaa cgtcccattt gcccgagact     3060

gaaggatttc tcaggctgtg gacatttaat gccaaaacca ggaatatccg gggcaaagca     3120

ggctgtgttg ttcgcctttg tggagccagg cagtgtgtgg cccagggaaa gctgcgtttc     3180

atggaggctt ccaggaggct gccctgtaaa gccaggcagg tggcttcaag tgccattcct     3240

gcaagtgccc ctgcttcagc tctcaggccc atccaatgcc tcgagcccac gggggtgtcc     3300

cggcaggtct gcgtcatcac gacccagtaa cgctgctggc tgtgtcctca tgccctcttc     3360

ctctggctgg ccagtcatgg gaagtcctgt tggttgagtc atctttgtca cttctacacc     3420

tttgagtatg tacaggctga atgttgagtg atgccccccc accctctcaa taaacacaca     3480

cacacacaca cacacacaca cacacacaca caatgttatt aggcacagca gctccatcct     3540

gctccctgag aatggcagtg caggcacaga gaagagcagt tgggaagaca ggcagctggt     3600

ctaccctgtc cccgcacact tcacaggcac tccactgctt ggcaggaatt ctgcatggca     3660

tctgccacgc atgctcacag ggtgaaaaat caagctgtca ctctgcaaaa tctaaaaacc     3720

ctggaaaggt ctataagatg acattagacc cagttaagaa gcaagtgtca cctgagttgg     3780

ccatgcaatg aatgaatatt ataagcagta ttggagaact aggcggttgc ttactaagaa     3840

gtgtcttgga aacattcgag ttcatacagt gcatgacaaa gtaatagaag gctgcaagcg     3900

ctgaaaatgc acccgaatct ggtacctagg atgagtacat gaatagtgat gaatagccct     3960

ttgtgctgtg tgctatatac aaccatttgc attcagaaag cagcatttga agctgagttc     4020

cattactggt gattgaagta ttttcaggag cagatacatg tggtgcatgt tatatgcact     4080

tagtttgaaa gtatccctca cccaaaaagt gcagaacctc tgaaaggtga gccgtggtgc     4140

aggtgccccc ctcgctgttc gggtcagttc ttggccatgc ttggcctgtc acacgccggg     4200

tctcaacaac atcgtgcgag gagacagtga ctggtttcag cccaagagtc aactgttgag     4260

catgacatca ggaagcctgt actgtcctga tcccaccagg cttgggttaa tttcctattg     4320

cttcagagaa agagaggcgc tcttgtgctt ttgagagagc tctcatgtta aaaagaggtt     4380

gtctttgcac tgcgcttggt atgatttgtt ttcttataaa acaggaagag aacctagaat     4440

gtgcctttcg tgaaggtctg acaaatgggg tctcagagtc ctaggacccg caccaaggtc     4500

agagtccacc tgtagaggct gagcatttct acatgcaccc agggtgctgg gctgaggcta     4560

agggtggacg cgtagacccc atcacaggct tccttcctga gcccaagtcc cccatttggt     4620

cactatccct tctcagagca agtggattct cttttcctca cttggagtat tcaatgttga     4680

agtagtggcc tggagtggcc tttccctcag ctgcctgtct gggctccctg gcttcccgga     4740

tcttcatctc atacgtgagg caataggagg agtttctatt cattgagaca aacagtgagc     4800

gggcaccaac aggccagcag cttggccctt ttcacagagg tggccttgga gtctggagtc     4860

tgggcagctg tctgcctctc tacggctctg cttcccagcg ggcacacggg tccggagcct     4920

cagaatgaag tggtgcagag gcgcagggca cacctaggag aagctcaatg accaccaaag     4980

cccttgagga gagacggggt ttgctgtgtt agagaaatgg caacccccag gaccatgcac     5040

ggctctggca gtgcacagtg gctgattttc accagttcct cctacccctg cctctgtcgg     5100

agactagaaa acattctacc ccttcaggtc ttcttttaaa agaaaagagc tatggcaaag     5160

cgtgccatac aaagttaaaa aaaggaagag tggctttgcg ttcttgacca tggccacaat     5220

tctggtcact tctagcatct gaccttgaga acggtgtaga gtctctgagc caccgctggc     5280

ctttgagaga gtctcactct ccagctagct ctttgtgtag tgtccagggc cccggcagtc     5340

aggatagagc gagcaaaaga agatggacag tggacagggc gcagtggctc acgcctgtaa     5400

tcccagcgct ttgggagagc gaggcgggca gatcacaagg tcaagagatc aagaccattc     5460

tggccaacat ggtgaaaccc tgtttctact aaaaatacaa aaattagctg ggcatggtgg     5520

tgcgtgcctg taatcccagc tactcgggag gctgaggcag gagaatcgct tgaacccggg     5580

aggcagaggt tgcagtgagc cgagatcgtg ccactgcact ccagcctggg tgacagagca     5640

agactccgtc tcaaaaaaga tggccatgct ggccaaggct gggctcatag gaaatatctg     5700

tagtaggatg aaaggaatct ggcctaggga gccccggact cggtttacct accccgtact     5760

catcccactc atctgtctac cctagtgtcc atcatgccct ggatgaatcg taggtgggag     5820

ggacagaagc cgagaacacc aggcacacgg ggtgggggga atggggggag cccaggtgat     5880

cccctttgga aagtggattg atcctctccc ctgtggaatg acagcttaac ctgattaacc     5940

cactggggct tgctatttta tgagcatttt taaacagaaa ggaaagatga tatcccagtg     6000

caggtagact ttatttttga aagcatcgtg gcccctcacc tctccctctc ccccagaacc     6060

ttggccagaa ttgagtcttc gcgttgggga ggccacgctg gaaccattgc tctagggctg     6120

aaggtggaag tagggccact gccgcagctt cagccagagc cctcgctgct tcgcagaatt     6180

taacaagcac acgactggga ttcctttgga tatgagaaag gaaggcaagt gcgggcaaag     6240

ggaagctcct cccgtttttc ataaacagaa gtaagatgtc ctctttccca ggtttgcaca     6300

atcacttctg gcaaattaat tgaaggtcct tgaattcagc cagtgcacga aacctttgca     6360

tgttcttctg aaactgtact tcttccctat tctgtctacc cacactctgc gaactttgcc     6420

ttttccttaa acacattcca gaccaaacac tgttcagttt gttaaaaaaa aaaaaaaaaa     6480

aaaaagatgt atatacctgt atgtgatcca ccaccctttt gaggggcacc tggtcctcgg     6540

ttggggctgc aggtgtgcct gacatttgca aaagatattc cagtctttcg atgttcagaa     6600

ttgaaaatgt ggagatagaa aagctcaaac agactcctaa aaggagggtt tctttcctga     6660

agactccaag aaaatgagtg tgcagatgag ttagcttgac aacctcaact ctggggagca     6720

ggcaggcggt ctgaggaaga taagggccca cgccccactc acctggcacc tgttcggtgg     6780

tcccggggca tcatggtctg cagctctggg cccccagccc cactgtgaag tcagtcctgc     6840

atgctggccg aggcccggcc acctcccgat gcctccagag tcagtgggaa ggagtcagcc     6900

cttcccagac ttccccgcca cctccagcag gagcagctca gtttgtggct ctgggagctc     6960

cgcttttgca aacccaaaaa ggctgtgcat ttggaagcca aacgctcagc atgcggctgc     7020

cgagtctggt tttgtggaca aagcaaactg tggaatggct tctcggtgtc tgtataaagg     7080

gacaaacggt tgcattcacc ctttgtacta taacaccgct tctgcattcg ccatatccgt     7140

tttttaacct ttttgtctcc ggggaacttc tcattcgatt attatgtctt ctgatgattt     7200

gccatgttat tttaaaggtg attttatttt cttatggaca ggaaaaaaga aaatgaggag     7260

gagttggttt tactcttaga gataagactt cagcaggggc tcagaaaccc caaactctag     7320

ttaaattgct tctcggagga aaatcttaat ctagacagat tcagattccc aggctctcct     7380

ggaagccctg cacttcaggg cacaggggcc ctgggacgtg gttggcagcc aggctgcgag     7440

agagctaaaa aggaacaaga acatcagctc ggatgtttgt ctctcagccc tgacacctgc     7500

cactctcctt cccggggcac ttggccctat cagagggaca tgaaatgctg tccgaatggt     7560

ggcagaaatg cagcgacatt gcatgcagca gagtctttgc ttcgaaagat ggggcgccat     7620

gtttcagaga acatttatct tagtcccacg ttcaggtgag aagacctcaa aggtaccctc     7680

tgtccagaat aaacattgga acaatctctc aattggcttt tgtcactaca cataatgtaa     7740

tctcccttct ttcagctccc ccaacagtga gcatgcttcc caaaaaatta caacatcaaa     7800

accaggaatg tccccgcatc tactattacc aggcttgcaa ttggttcaat tttcccataa     7860

aaacatgttt gtccaaaaga agggaaactg tgaatttatt ccatgcatgt aataaactct     7920

gcaagaagtt taacccacat aggtttgcgg cactgcaaaa ttgttcatgg gtctatgtag     7980

caaatgattc tctgccttga caatcatgta tacatatcaa gatttctatc ataatgataa     8040

tgagattgat gacttcctgt tttcctccaa taaagacaat taatcacctt caaaaaaaaa     8100

aaaaaa                                                                8106


<210>  2217
<211>  1734
<212>  DNA
<213>  homo sapiens

<400>  2217
ccggcgtcgg cggcgcgcgc gctccctcct ctcggagaga gggctgtggt aaaagccgtc       60

cggaaaatgg ccgccgccgc cgccgccgcg ccgagcggag gaggaggagg aggcgaggag      120

gagagactgg aagaaaagtc agaagaccag gacctccagg gcctcaagga caaacccctc      180

aagtttaaaa aggtgaagaa agataagaaa gaagagaaag agggcaagca tgagcccgtg      240

cagccatcag cccaccactc tgctgagccc gcagaggcag gcaaagcaga gacatcagaa      300

gggtcaggct ccgccccggc tgtgccggaa gcttctgcct cccccaaaca gcggcgctcc      360

atcatccgtg accggggacc catgtatgat gaccccaccc tgcctgaagg ctggacacgg      420

aagcttaagc aaaggaaatc tggccgctct gctgggaagt atgatgtgta tttgatcaat      480

ccccagggaa aagcctttcg ctctaaagtg gagttgattg cgtacttcga aaaggtaggc      540

gacacatccc tggaccctaa tgattttgac ttcacggtaa ctgggagagg gagcccctcc      600

cggcgagagc agaaaccacc taagaagccc aaatctccca aagctccagg aactggcaga      660

ggccggggac gccccaaagg gagcggcacc acgagaccca aggcggccac gtcagagggt      720

gtgcaggtga aaagggtcct ggagaaaagt cctgggaagc tccttgtcaa gatgcctttt      780

caaacttcgc cagggggcaa ggctgagggg ggtggggcca ccacatccac ccaggtcatg      840

gtgatcaaac gccccggcag gaagcgaaaa gctgaggccg accctcaggc cattcccaag      900

aaacggggcc gaaagccggg gagtgtggtg gcagccgctg ccgccgaggc caaaaagaaa      960

gccgtgaagg agtcttctat ccgatctgtg caggagaccg tactccccat caagaagcgc     1020

aagacccggg agacggtcag catcgaggtc aaggaagtgg tgaagcccct gctggtgtcc     1080

accctcggtg agaagagcgg gaaaggactg aagacctgta agagccctgg gcggaaaagc     1140

aaggagagca gccccaaggg gcgcagcagc agcgcctcct caccccccaa gaaggagcac     1200

caccaccatc accaccactc agagtcccca aaggcccccg tgccactgct cccacccctg     1260

cccccacctc cacctgagcc cgagagctcc gaggacccca ccagcccccc tgagccccag     1320

gacttgagca gcagcgtctg caaagaggag aagatgccca gaggaggctc actggagagc     1380

gacggctgcc ccaaggagcc agctaagact cagcccgcgg ttgccaccgc cgccacggcc     1440

gcagaaaagt acaaacaccg aggggaggga gagcgcaaag acattgtttc atcctccatg     1500

ccaaggccaa acagagagga gcctgtggac agccggacgc ccgtgaccga gagagttagc     1560

tgactttaca cggagcggat tgcaaagcaa accaacaaga ataaaggcag ctgttgtctc     1620

ttctccttat gggtagggct ctgacaaagc ttcccgatta actgaaataa aaaatatttt     1680

tttttctttc agtaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa           1734


<210>  2218
<211>  3569
<212>  DNA
<213>  homo sapiens

<400>  2218
ggcagtgtag ctgcgagaac ctttgcacgc gcacaaacta cggggacgat ttctgattga       60

tttttggcgc tttcgatcca ccctcctccc ttctcatggg actttgggga caaagcgtcc      120

cgaccgcctc gagcgctcga gcagggcgct atccaggagc caggacagcg tcgggaacca      180

gaccatggct cctggacccc aagatcctta agttcgtcgt cttcatcgtc gcggttctgc      240

tgccggtccg ggttgactct gccaccatcc cccggcagga cgaagttccc cagcagacag      300

tggccccaca gcaacagagg cgcagcctca aggaggagga gtgtccagca ggatctcata      360

gatcagaata tactggagcc tgtaacccgt gcacagaggg tgtggattac accattgctt      420

ccaacaattt gccttcttgc ctgctatgta cagtttgtaa atcaggtcaa acaaataaaa      480

gttcctgtac cacgaccaga gacaccgtgt gtcagtgtga aaaaggaagc ttccaggata      540

aaaactcccc tgagatgtgc cggacgtgta gaacagggtg tcccagaggg atggtcaagg      600

tcagtaattg tacgccccgg agtgacatca agtgcaaaaa tgaatcagct gccagttcca      660

ctgggaaaac cccagcagcg gaggagacag tgaccaccat cctggggatg cttgcctctc      720

cctatcacta ccttatcatc atagtggttt tagtcatcat tttagctgtg gttgtggttg      780

gcttttcatg tcggaagaaa ttcatttctt acctcaaagg catctgctca ggtggtggag      840

gaggtcccga acgtgtgcac agagtccttt tccggcggcg ttcatgtcct tcacgagttc      900

ctggggcgga ggacaatgcc cgcaacgaga ccctgagtaa cagatacttg cagcccaccc      960

aggtctctga gcaggaaatc caaggtcagg agctggcaga gctaacaggt gtgactgtag     1020

agttgccaga ggagccacag cgtctgctgg aacaggcaga agctgaaggg tgtcagagga     1080

ggaggctgct ggttccagtg aatgacgctg actccgctga catcagcacc ttgctggatg     1140

cctcggcaac actggaagaa ggacatgcaa aggaaacaat tcaggaccaa ctggtgggct     1200

ccgaaaagct cttttatgaa gaagatgagg caggctctgc tacgtcctgc ctgtgaaaga     1260

atctcttcag gaaaccagag cttccctcat ttaccttttc tcctacaaag ggaagcagcc     1320

tggaagaaac agtccagtac ttgacccatg ccccaacaaa ctctactatc caatatgggg     1380

cagcttacca atggtcctag aactttgtta acgcacttgg agtaattttt atgaaatact     1440

gcgtgtgata agcaaacggg agaaatttat atcagattct tggctgcata gttatacgat     1500

tgtgtattaa gggtcgtttt aggccacatg cggtggctca tgcctgtaat cccagcactt     1560

tgataggctg aggcaggtgg attgcttgag ctcgggagtt tgagaccagc ctcatcaaca     1620

cagtgaaact ccatctcaat ttaaaaagaa aaaaagtggt tttaggatgt cattctttgc     1680

agttcttcat catgagacaa gtcttttttt ctgcttctta tattgcaagc tccatctcta     1740

ctggtgtgtg catttaatga catctaacta cagatgccgc acagccacaa tgctttgcct     1800

tatagttttt taactttaga acgggattat cttgttatta cctgtatttt cagtttcgga     1860

tatttttgac ttaatgatga gattatcaag acgtagccct atgctaagtc atgagcatat     1920

ggacttacga gggttcgact tagagttttg agctttaaga taggattatt ggggcttacc     1980

cccaccttaa ttagagaaac atttatattg cttactactg taggctgtac atctcttttc     2040

cgatttttgt ataatgatgt aaacatggaa aaactttagg aaatgcactt attaggctgt     2100

ttacatgggt tgcctggata caaatcagca gtcaaaaatg actaaaaata taactagtga     2160

cggagggaga aatcctccct ctgtgggagg cacttactgc attccagttc tccctcctgc     2220

gccctgagac tggaccaggg tttgatggct ggcagcttct caaggggcag cttgtcttac     2280

ttgttaattt tagaggtata tagccatatt tatttataaa taaatattta tttatttatt     2340

tataagtaga tgtttacata tgcccaggat tttgaagagc ctggtatctt tgggaagcca     2400

tgtgtctggt ttgtcgtgct gggacagtca tgggactgca tcttccgact tgtccacagc     2460

agatgaggac agtgagaatt aagttagatc cgagactgcg aagagcttct ctttcaagcg     2520

ccattacagt tgaacgttag tgaatcttga gcctcatttg ggctcagggc agagcaggtg     2580

tttatctgcc ccggcatctg ccatggcatc aagagggaag agtggacggt gcttgggaat     2640

ggtgtgaaat ggttgccgac tcaggcatgg atgggcccct ctcgcttctg gtggtctgtg     2700

aactgagtcc ctgggatgcc ttttagggca gagattcctg agctgcgttt tagggtacag     2760

attccctgtt tgaggagctt ggcccctctg taagcatctg actcatctca gagatatcaa     2820

ttcttaaaca ctgtgacaac aggatctaaa atggctgaca catttgtcct tgtgtcacgt     2880

tccattattt tatttaaaaa cctcagtaat cgttttagct tctttccagc aaactcttct     2940

ccacagtagc ccagtcgtgg taggataaat tacggatata gtcattctag gggtttcagt     3000

cttttccatc tcaaggcatt gtgtgttttg ttccgggact ggtttggctg ggacaaagtt     3060

agaactgcct gaagttcgca cattcagatt gttgtgtcca tggagtttta ggaggggatg     3120

gcctttccgg tcttcgcact tccatcctct cccacttcca tctggcgtcc cacaccttgt     3180

cccctgcact tctggatgac acagggtgct gctgcctcct agtctttgcc tttgctgggc     3240

cttctgtgca ggagacttgg tctcaaagct cagagagagc cagtccggtc ccagctcctt     3300

tgtcccttcc tcagaggcct tccttgaaga tgcatctaga ctaccagcct tatcagtgtt     3360

taagcttatt cctttaacat aagcttcctg acaacatgaa attgttgggg ttttttggcg     3420

ttggttgatt tgtttaggtt ttgctttata cccgggccaa atagcacata acacctggtt     3480

atatatgaaa tactcatatg tttatgacca aaataaatat gaaacctcat attaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                                       3569


<210>  2219
<211>  412
<212>  DNA
<213>  homo sapiens

<400>  2219
acagtgggca gcccgatttt ctgctgagta ggcgctgtga tttcagaatg tctgggcgag       60

gtaaaggtgg caaggggctg ggtaagggag gcgccaagcg ccaccggaag gtgctgcggg      120

acaatatcca aggcattaca aagccggcga ttcgccgtct cgcccgacgt gggggcgtca      180

agcgcatttc tggtctcatc tacgaggaga cccggggagt cctcaaagtc ttcctggaga      240

acgtgatccg tgacgcggtg acttacacgg agcacgccaa gcgcaagacc gtcacggcca      300

tggatgtggt gtacgcgctg aaacgccagg gtcgcaccct ttatggtttc ggcggttgag      360

ctgtccccac agcttctcta cagactccaa aaggcccttt tcagggcccc ca              412


<210>  2220
<211>  396
<212>  DNA
<213>  homo sapiens

<400>  2220
agaagctgtc tatcgggctc cagcggtcat gtccggcaga ggaaagggcg gaaaaggctt       60

aggcaaaggg ggcgctaagc gccaccgcaa ggtcttgaga gacaacattc agggcatcac      120

caagcctgcc attcggcgtc tagctcggcg tggcggcgtt aagcggatct ctggcctcat      180

ttacgaggag acccgcggtg tgctgaaggt gttcctggag aatgtgattc gggacgcagt      240

cacctacacc gagcacgcca agcgcaagac cgtcacagcc atggatgtgg tgtacgcgct      300

caagcgccag gggcgcaccc tgtacggctt cggaggctag gccgccgctc cagctttgca      360

cgtttcgatc ccaaaggccc tttttagggc cgacca                                396


<210>  2221
<211>  2105
<212>  DNA
<213>  homo sapiens

<400>  2221
agatctcatt ccgcctccct ctgtcgtcgc cccttcccaa ttctcgcgag acctcaagga       60

gcacagcttc tgcgcaccgc acgatactgg gagtccaggc gccaagggag ggggaaggga      120

aaaggggaaa cggtgcaaac ggcgtggccg ccatcttgct tgtgcccccg cttcgcgcgc      180

gctccgttct ccgtgacgca cacttccccc tcccctccgc cgcgcctggg cctctgcatt      240

gcccgactcc gtaggagcgc gggggcggct cctgctcttc ctggactcct gagcagagtt      300

gtcgagatgt ccacagaagg aggatttggt ggtactagca gcagtgatgc ccagcaaagc      360

ctacagtcgt tctggcctcg ggtcatggaa gaaatccgga atttaacagt gaaagacttc      420

cgagtgcagg aactcccact ggctcgtatt aagaagatta tgaaactgga tgaagatgtg      480

aagatgatca gtgcagaagc gcctgtactc tttgccaagg cagcccagat ttttatcaca      540

gagttgactc ttcgagcctg gattcacaca gaagataaca agcgccggac tctacagaga      600

aatgatatcg ccatggcaat tacaaaattt gatcagtttg attttctcat cgatattgtt      660

ccaagagatg aactgaaacc tccaaagcgt caggaggagg tgcgccagtc tgtaactcct      720

gccgagccag tccagtacta tttcacgctg gctcagcaac ccaccgctgt ccaagtccag      780

ggccagcagc aaggccagca gaccaccagc tccacgacca ccatccagcc tgggcagatc      840

atcatcgcac agcctcagca gggccagacc acacctgtga caatgcaggt tggagaaggt      900

cagcaggtgc agattgtcca ggctcagcca cagggtcaag cccaacaggc ccagagtggc      960

actggacaga ccatgcaggt gatgcagcag atcatcacta acacaggaga gatccagcag     1020

atcccggtgc agctgaatgc cggccagctg cagtatatcc gcttagccca gcctgtatca     1080

ggcactcaag ttgtgcaggg acagatccag acacttgcca ccaatgctca acagattaca     1140

cagacagagg tccagcaagg acagcagcag ttcagccagt tcacagatgg acagcagctc     1200

taccagatcc agcaagtcac catgcctgcg ggccaggacc tcgcccagcc catgttcatc     1260

cagtcagcca accagccctc cgacgggcag gccccccagg tgaccggcga ctgagggcct     1320

gagctggcaa ggccaaggac acccaacaca atttttgcca tacagcccca ggcaatgggc     1380

acagccttcc tccccagagg acccggccga cctcagcgcc tcctgcaggc taggacactg     1440

gtgcactaca ccccatgcct gggggccgag attctccagc agaaagatgc aatatttttt     1500

gtttcctttt tttccatttt tttctctaag gaatcaatat ttcaatatgt tgagtgtgtg     1560

tccaatgcta tgaaattaaa atattaaata acatatttat ggcattttct tgaagagtgt     1620

ggttgaagaa atatttctcc ttttgttttt cttttttttt tgtttgttac tgccacttct     1680

ttttaggagc aaatctcccc aggggtgtac ggtatttctt gactctggga acagctgcta     1740

cccccaagac ttgccacgtt gttctgccct cagatggaat taggtgaatg tgtgtagctg     1800

ctttttcact cgtggtcctc tccccatccc ttgctctgac cccagagctc tgtgtatttg     1860

catccagagg ccatggaaac attctttgca tttaagagac agatttattc cctgtggaga     1920

gtgggtggat tcattgccac actcttttct cccagggacc caggaaacta ggactttgtg     1980

tgtttgctgc ccacctccct tttatttttt aaatgcatta aaaactgtgc tagtctcctt     2040

tgcatggact tcaagctgca tgaaatgcaa taaatctcat tttagataaa aaaaaaaaaa     2100

aaaaa                                                                 2105


<210>  2222
<211>  5069
<212>  DNA
<213>  homo sapiens

<400>  2222
gaggcggagg cggccccggg ctcgggcggc tgggatggag cagaagagcg cggagcaccg       60

gagggcacgc agctgacgga gctgcgctgc gttcgcctcg tttgcctcgc gccctccact      120

ggagctgttc gcgcctcccg gctcccaccg cagcccaccc ggcagaggag tcgctaccag      180

cgcccagtgc gctctgtcag tccgcaaact ccttgccgcc cgccccgggc tgggcaccaa      240

ataccaggct accatggtct acaagactct cttcgctctt tgcatcttaa ctgcaggatg      300

gagggtacag agtctgccta catcagctcc tttgtctgtt tctcttccga caaacattgt      360

accaccgacc accatctgga ctagctctcc acaaaacact gatgcagaca ctgcctcccc      420

atccaacggc actcacaaca actcggtgct cccagttaca gcatcagccc caacatctct      480

gcttcctaag aacatttcca tagagtccag agaagaggag atcaccagcc caggttcgaa      540

ttgggaaggc acaaacacag acccctcacc ttctgggttc tcgtcaacaa gcggtggagt      600

ccacttaaca accacgttgg aggaacacag ctcgggcact cctgaagcag gcgtggcagc      660

tacactgtcg cagtccgctg ctgagcctcc cacactcatc tcccctcaag ctccagcctc      720

atcaccctca tccctatcaa cctcaccacc tgaggtcttt tctgcctccg ttactaccaa      780

ccatagctcc actgtgacca gcacccaacc cactggagct ccaactgcac cagagtcccc      840

gacagaggag tccagctctg accacacacc cacttcacat gccacagctg agccagtacc      900

ccaggagaaa acacccccaa caactgtgtc aggcaaagtg atgtgtgagc tcatagacat      960

ggagaccacc accacctttc ccagggtgat catgcaggaa gtagaacatg cattaagttc     1020

aggcagcatc gccgccatta ccgtgacagt cattgccgtg gtgctgctgg tgtttggagt     1080

tgcagcctac ctaaaaatca ggcattcctc ctatggaaga cttttggacg accatgacta     1140

cgggtcctgg ggaaactaca acaaccctct gtacgatgac tcctaacaat ggaatatggc     1200

ctgggatgag gattaactgt tctttattta taagtgctta tccagtagaa ttaataagta     1260

cctgatgcgc attgaacgac aatcttaagc cctgttttgt tggtatggtt gtttttgttt     1320

tcctccctct cctctggctg ctacaacttc ccctttctgg tacaagaaga accattcttt     1380

aaaggtgagt ggaggctgat ttgcagctga agtgggccag ccttgcacca gccaggccag     1440

accaccatgg tgaaggcttc tttccccact gcaggaccca ctttgagaag gaccgaggag     1500

gaggatttgg gttgttttgt taggggttac tttcagggga acatttcatt tgtgttattt     1560

cttaaacttc tatttaggaa attacattaa gtattaatga ggggaaagga aatgagctct     1620

acgaggattt caccctgcat gggagagagc agggttttct cagattcctt tttaatctct     1680

atttatctgg ttgtttctga caggatgctg cctgcttggc tctacaagct ggaaagcagc     1740

ttcttagctg cctaattaat gaaagatgaa aataggaagt gccctggagg gggccagcag     1800

gtcacggggc agaatctctc aggttgctgt gggatctcag tgtgccccta cctgttctcc     1860

cctccaggcc acctgtctct gtaaaggatg tctgctctgt tcaaaaggca gctgggatcc     1920

cagcccacaa gtgatcagca gagttgcatt tccaaagaaa aaggctatga gatgagctga     1980

gttatagaga gaaagggaga ggcatgtacg gtgtggggaa gtggaagaga agctggcggg     2040

ggagaaggag gctaacctgc actgagtact tcattaggac aagtgagaat cagctattga     2100

taatggccag agatatccac agcttggagg agcccagaga ccgtttgctt tatacccaca     2160

cagcaactgg tccactgctt tactgtctgt tggataatgg ctgtaaaatg tttaaaaaca     2220

aaacaaaaca aaaaagaggc actagtctat ctgcaattac tcaacgaggc attttcatag     2280

gaaacagact atgattaatc catttattct tcccacacac ttaccttact aagtctttgc     2340

tttaataaat gagcaaccct gggtatagtc ttaaaattct gcacaataaa ttttgagaaa     2400

gaattgttcc tctttgtagg tatctgtgta ttgcaatcat tctcaaccag gaggtgattt     2460

tgccccctga ctccacccca gggacattca aaaatgtctg gtgacagttt tcattgtcat     2520

gacttggggg tgctactaga agccaggaat gctgccaaac attctaccat gcacagcaca     2580

acctacaaca gcaaagaatc atccacccca aaatatcagt agtgccgaga ttgagaaacc     2640

ctgatttatc acaatgccca ctgtgacaga acaagacact cacagattag tgatacgttt     2700

tatttttaac aaaatgaaat gatgtgttaa gtttttattt ccaaagtgtt tagtttattg     2760

gctgatgggt tgttcttggt atgcatggtg acctttttat ttctgtgtgc ttcctagaga     2820

gctttatttc atggcgacaa ctctgtcttc ttgtaacagc tgatattagc aagcagcatc     2880

ttatgtcctg atttcatata gtagaaaaca aacattgggt ccgacttcaa aatgtgttgt     2940

attgtcctac agtgtcataa agaacctgaa aatgaacttt tgtttctaaa gttggacctt     3000

gctgccatga ctgtttagtt tacagaaact tgaccccggc tcatcctgtc tctggctgtg     3060

gcccggcaaa gcactgaaaa cccctctggt ctcagagaca gtaggggcag tgccactttc     3120

tacaacctgc caacccacac actggagtaa ttctgaaaaa aattattcct aaactctcta     3180

agtgtggacg gagaatgagc aagccccaga agtattttac aaccagagtg ggtaatgagg     3240

agggggctta ctggaatcgt catatctctg aatattgaaa acaacaacta aaaaagtgga     3300

ccttctcaga aaaaaagggc agcaaatgac caagggcgcc ccttctggcc gtgcttggct     3360

tgagtaactg tctctctttc cccaccccca tcacagggct ttcagtttgg caaaggaaaa     3420

gcagataaaa acagaacatt ccatatgttt ctttctccat cggccaaaaa cattttgaca     3480

caatgtttgt gaaacacctt tggagaggtg cacttctgaa tgctgcctct gccgtaaatc     3540

ctggggcaag ggatcagcct cttcccagga accatcgcct tctataaacc gtgaactcaa     3600

gcaggcattt tttttttctt accgaaaggc tgctattgtg caagggcaca taatgggtct     3660

gttgctctta ttggcttcca aatgtgcatg gcaaagagag agatgtgggc ctagagcaga     3720

tatattcagc aaggtgacag cttcccataa caattctaac acttcttatc ttatgtgaga     3780

ataaaatatt taagggttga accttatttt gccaaatgta tcttttctgc ttttgaattg     3840

ggcagaagat tttagcaact atattctaca aatgttactt ataacacaca cacacacatc     3900

tgaaatatat gccgaaaatt gacgtctttg acctcaggga gagcacctgt ccaggtctgc     3960

ctaaaggaaa tggctccagt gggtctaaac aaccacatcc tatccatgga taggtctagt     4020

cataacactt tagagagaat gtcagagcag gagggaggca agccgcctct tctcggccat     4080

cgactgcaga tgatgaaaga gcgggattca actttgtttt cttttcctgt ggccccagtg     4140

aaacctcctg ccctccctgc acgtctgtgt cttcatttct aaaatggggg tgatgctttc     4200

atattgacct caccccatac tacctcacag atgtgttgtg aggattaata aaattatgtc     4260

tatggtattt tcagtttctg gagaaaaata cttatagaca gtttaactat tacatagata     4320

tataagtgat ctcagtttct tgtttgctgt gatactaatg tgttgtttta acttattcca     4380

taaaatgaca gttgtgtcct agccacatca gacagctatc taagctctgg actacccctt     4440

tgtgcagctg aatcactgca gggttgacca tgcctggtgc cacagccatg gtttccattt     4500

ctagatgaaa ggatggccta ggacataggt ctcaaagact cttggatcag aatcaggaga     4560

ttagggaaaa caggatggat acctgagcac taacagcagt agacgtagac ctctgtcctt     4620

taccatctga ggtcttctgg attctttgtg gggttaattt tgatttgatg tcatctgttt     4680

gcccttcatc ttgcttgcaa gtgtgcatgg ttcaatccct cacatccagg aaatgaattt     4740

tgcaattggg ccagatgcta atttgcacgt tgattcacct tctttgcctt taagcctttt     4800

ttttcttttt tttttttttg gcaaatgaat gtaccatttc aactttgatt ttaatagtgc     4860

tagttgatat tggtaataat gctaaccaag agatcaatgc cagatttttc tcttggggta     4920

agttagctga agtcatttaa agatggaaag gtgggaaaat tctttgatat ttgatgtcat     4980

tgtatccaca tttgttgtaa gacatattgc ataccaatta taattatatc aattaaagtt     5040

gataaaagct tccaaaaaaa aaaaaaaaa                                       5069


<210>  2223
<211>  1095
<212>  DNA
<213>  homo sapiens

<400>  2223
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgaggaa aggccctggt ctccggagtt tcctcgcatt aaaggagaga gagagagagt     1020

actcttttgg gcaacggccc tccaaaattg cccccacatt ggctgcctta taaatatgtc     1080

tgtgtgttga ctggt                                                      1095


<210>  2224
<211>  2032
<212>  DNA
<213>  homo sapiens

<400>  2224
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtaatg     1560

ggactcctga ccaaccacgg tggggtacct catcagcccc agactgatta cgcgctctcc     1620

cctctcaccg ggggtctgga acctaccacc acggtgtcgg ccagctgcag tcagagacta     1680

gaccatatga agagcttgga cagtctgcca acatctcagt cctactgtcc acccacctat     1740

agcaccacag gctacagtat ggaccctgtc acaggctacc aatatgggca gtatggacaa     1800

agtaagcctt ggacttttta gggggcaatt tctcctggaa gggagataaa ctcaactctt     1860

ccttaagaaa ggtgaattag aggcaagatt aagccacaca tgccggtatc aatttttttt     1920

tttttttgca aagccagctg actgttccag caggggcttc cttgtgtaat tattttctta     1980

actgatgtca acaacatctt gcggttatta attgttgaga cgtgaaacct ga             2032


<210>  2225
<211>  16064
<212>  DNA
<213>  homo sapiens

<400>  2225
ccgcgcgtcc ctgtgcgtcc ccgggtccct gcgggcgggc gggcgcggtc gccgccgagc       60

aacccggcct gcgcccggca cgactgtaga tgtcaggctt tgcccgggga gccgagcggc      120

agcggggctg tgagtttcaa attaaccttc cgctttgttg ctgtgtaatg tggatccccg      180

aaggcccccc gccccgcccg ccccccttcc ccgggcggtg cgcgctgcaa actgcgagtt      240

gggcttcatt tacataaagc gattccgggc gggcggcggc agaggaggag gcggcggcgg      300

cgggcaggcc ggggacccgg acgccagcgc cgcgccccgt gggtgaatcc ccgccgcgtc      360

ccggggacct ccctccgggg acgggccgac cgccagccct gccgccacca tgagctcccc      420

tcccctgtct ccgggccccc tgctcctgac cagagccacc tccgagtcct ggggccagcg      480

ggaggtgggg agcatgccgc ctggggtggg tgagctcggg gctcgggtgc cactggaatt      540

tcccgttgtt gcgcatggcg gcgcggcccc cggacctgca agtgccgcct ccctccggag      600

gtgcgcggag gcttggtgtg ccaggtccga gcctccgtac tgggtgcaat gaaagctcca      660

cgcaggcctt accatggaag gctgtgactc gcccgtcgtc tcggggaagg acaatgggtg      720

cggtatccct cagcaccagc aatggactga actcaacagc acccacctcc ctgacaaacc      780

cagtagcatg gagcagtcca caggcgagag ccacgggccc ttggacagcc tgagggcccc      840

cttcaatgag cgcctcgcgg agagcaccgc gtcggccggg cccccctccg agcccgccag      900

caaggaggtc acctgcaacg aatgttcggc ctcctttgcc agcctccaga cctacatgga      960

gcaccactgc cccagcgcgc gccccccgcc acccctgaga gaggagagcg ccagcgacac     1020

cggtgaggag ggggacgagg agagtgacgt ggagaacctg gccggggaga tcgtctacca     1080

gccggacggc tccgcgtaca ttgtggagag cctgagccag ctgacccagg gcgggggcgc     1140

ctgtgggagt ggcagtggca gtgggcctct cccctcgctt ttcctgaact ctctccctgg     1200

cgcggggggc aagcaagggg acccttcgtg tgctgcaccc gtgtacccgc agatcatcaa     1260

cactttccac atagcctcat ccttcgggaa atggtttgag ggcccagacc aggctttccc     1320

gaatacctca gccctggcgg ggctcagccc cgtcctgcac agcttccgcg tgtttgacgt     1380

gcgacacaaa agcaacaagg attacctgaa cagcgacggt tctgccaaaa gctcctgcgt     1440

atccaaagat gttcccaaca atgtggacct gtccaaattc gatggctttg tgctctatgg     1500

caagaggaag cccatcctga tgtgtttctt gtgcaaactc tcctttgggt acgtccgttc     1560

gtttgtgacc cacgcggtgc atgaccatcg aatgaccctg agcgaagacg agcggaaaat     1620

tcttagcaat aagaacatct ccgctatcat ccaagggatc ggcaaagaca aggaacccct     1680

tgtaagtttt ctggaaccaa aaaacaaaaa ctttcaacac cctttagttt ccacagctaa     1740

cctcataggc cccggacaca gtttttatgg taaatttagt ggcattcgaa tggaagggga     1800

ggaagctctc ccagcgggct ccgccgctgg ccccgagcag ccccaggctg gtctcttgac     1860

ccccagcacc ctgttgaacc ttggcgggct caccagctcg gtactgaaga cccccattac     1920

ctcagtcccc ctggggcctc tggcttccag tcctaccaaa tcctcagagg gcaaggactc     1980

tggggcggca gaaggagaga agcaggaagt gggcgacggg gattgcttct ctgagaaggt     2040

agagccagcc gaagaggagg cggaggagga agaggaggag gaagaggcgg aggaggagga     2100

ggaagaagag gaggaggaag aagaggagga ggaagacgag ggttgcaaag gactctttcc     2160

aagcgagttg gatgaggaac tggaggacag gccccatgag gagcctgggg ccgcagcagg     2220

tagtagcagc aaaaaggacc ttgctctctc aaaccaaagc atttctaact cccccttaat     2280

gcctaacgtg ctccagaccc tgtcgagggg cacagcttct actagttcta attctgcttc     2340

ttcctttgtt gtctttgatg gtgcgaacag gaggaatcgt ttaagcttta acagtgaggg     2400

cgtcagggcc aatgtggcag agggcggcag gaggctggac ttcgctgacg aaagtgccaa     2460

taaagacaat gccacagcac cagaaccaaa tgaaagcaca gagggtgacg atgggggctt     2520

cgttccccat caccagcacg ctggctccct ctgcgagctt ggggttgggg agtgcccctc     2580

ggggagtggc gtggagtgcc ccaaatgcga cacggtcctg ggctcctccc gctcgctggg     2640

cggccacatg accatgatgc attctcgtaa ctcgtgtaag acactcaagt gccccaagtg     2700

caactggcac tataagtacc agcagaccct ggaggcacac atgaaggaga agcacccgga     2760

gccggggggc tcctgtgtct actgcaaaag cgggcagccc cacccccggc tggcacgagg     2820

cgagagctac acgtgtggtt acaagccttt ccgctgcgag gtgtgtaact actccacaac     2880

taccaaaggc aacctcagta ttcatatgca gtctgacaag catctcaaca acatgcagaa     2940

cctgcagaat ggaggggggg agcaggtctt cagccacact gccggggcgg cggcggcggc     3000

ggtggctgcg gcggcggcgg cagccaatat cagtagctcc tgcggggccc cctcgccgac     3060

caaaccaaaa accaaaccca cctggcggtg cgaggtgtgt gattatgaga ccaacgtggc     3120

caggaacctc cgcattcaca tgaccagtga gaagcacatg cataacatga tgttactgca     3180

acagaacatg acccagatcc aacacaaccg ccacctgggc ctcggcagcc tgccctcacc     3240

cgccgaggcc gagctctacc aatactacct ggcccagaac atgaacctgc ccaacctgaa     3300

gatggacagt gctgcctcgg acgcccagtt catgatgagc ggattccagc tggatcccgc     3360

cgggcccatg gccgccatga cgcctgctct agtgggcggt gagatccccc tagacatgcg     3420

gctcgggggc gggcagctgg tgtcagagga gctgatgaac ctgggcgaga gcttcatcca     3480

gaccaacgac ccgtcgctga agctcttcca gtgcgccgtc tgcaacaagt tcacgacgga     3540

caacctggac atgctgggcc tgcacatgaa cgtggagcgc agcctgtcgg aggacgagtg     3600

gaaggcggtg atgggggact cataccagtg caagctctgc cgctacaaca cccagctcaa     3660

ggccaacttc cagctgcact gcaagacaga caagcacgtg cagaagtacc agctggtggc     3720

ccacatcaag gagggcggca aggccaacga gtggaggctc aagtgtgtgg ccatcggcaa     3780

ccccgtgcac ctcaagtgca acgcctgtga ctactacacc aacagcctgg agaagctgcg     3840

gctgcacacg gtcaactcca ggcacgaggc cagcctgaag ttgtacaagc acctgcagca     3900

gcatgagagt ggtgtagaag gtgagagctg ctactaccac tgcgttctgt gcaactactc     3960

caccaaggcc aagctcaacc tcatccagca tgtgcgctcc atgaagcacc agcgaagcga     4020

gagcctgcga aagctgcagc ggctgcagaa gggccttcca gaggaggacg aggacctggg     4080

gcagatcttc accatccgca ggtgcccctc cacggaccca gaagaagcca ttgaagatgt     4140

tgaaggaccc agtgaaacag ctgctgatcc agaggagctt gctaaggacc aagagggcgg     4200

agcatcgtcc agccaagcag agaaggagct gacagattct cctgcaacct ccaaacgcat     4260

ctccttccca ggtagctcag agtctcccct ctcttcgaag cgaccaaaaa cagctgagga     4320

gatcaaaccg gagcagatgt accagtgtcc ctactgcaag tacagtaatg ccgatgtcaa     4380

ccggctccgg gtgcatgcca tgacgcagca ctcggtgcaa cccatgcttc gctgccccct     4440

gtgccaggac atgctcaaca acaagatcca cctccagctg cacctcaccc acctccacag     4500

cgtggcacct gactgcgtgg agaagctcat tatgacggtg accacccctg agatggtgat     4560

gccaagcagc atgttcctcc cagcagctgt tccagatcga gatgggaatt ccaatttgga     4620

agaggcagga aagcagcctg aaacctcaga ggatctggga aagaacatct tgccatccgc     4680

aagcacagag caaagcggag atttgaaacc atcccctgct gacccaggct ctgtgagaga     4740

agactcaggc ttcatctgct ggaagaaggg gtgcaaccag gttttcaaaa cttctgctgc     4800

ccttcagacg cattttaatg aagtgcatgc caagaggcct cagctgccgg tgtcagatcg     4860

ccatgtgtac aagtaccgct gtaatcagtg tagcctggcc ttcaagacca ttgaaaagtt     4920

gcagctccat tctcagtacc atgtgatcag agctgccacc atgtgctgtc tttgtcagcg     4980

cagtttccga actttccagg ctctgaagaa gcaccttgag acaagccacc tggagctgag     5040

tgaggctgac atccaacagc tttatggtgg cctgctggcc aatggggacc tcctggcaat     5100

gggagacccc actctggcag aggaccatac cataattgtt gaggaagaca aggaggaaga     5160

gagtgacttg gaagataaac agagcccaac gggcagtgac tctgggtcag tacaagaaga     5220

ctcgggctca gagccaaaga gagctctgcc tttcagaaaa ggtcccaatt ttactatgga     5280

aaagttccta gacccttctc gcccttacaa gtgtaccgtc tgcaaggaat ctttcactca     5340

aaagaatatc ctgctagtac actacaattc tgtctcccac ctgcataagt taaagagagc     5400

ccttcaagaa tcagcaaccg gtcagccaga acccaccagc agcccagaca acaaaccttt     5460

taagtgtaac acttgtaatg tggcctacag ccagagttcc actctggaga tccatatgag     5520

gtctgtgtta catcaaacca aggcccgggc agccaagctg gaggctgcaa gtggcagcag     5580

caatgggact gggaacagca gcagtatttc cttgagctcc tccacgccaa gtcctgtgag     5640

caccagtggc agtaacacct ttaccacctc caatccaagc agtgctggca ttgctccaag     5700

ctctaactta ctaagccaag tgcccactga gagtgtaggg atgccacccc tggggaatcc     5760

tattggtgcc aacattgctt ccccttcaga gcccaaagag gccaatcgga agaaactggc     5820

agatatgatt gcatccaggc agcagcaaca acagcagcag caacagcaac aacaacaaca     5880

acaacaacaa caacaagcac aaacgctggc ccaggcccag gctcaagttc aagctcacct     5940

gcagcaggag ctgcagcaac aggctgccct gatccagtct cagctgttta accccaccct     6000

ccttcctcac ttccccatga caactgagac cctgctgcaa ctacagcagc agcagcacct     6060

cctcttccct ttctacatcc ccagtgctga gttccagctt aaccccgagg tgagcttgcc     6120

agtgaccagt ggggcactga cactgactgg gacaggccca ggcctgctgg aagatctgaa     6180

ggctcaggtt caggtcccac agcagagcca tcagcagatc ttgccgcagc agcagcagaa     6240

ccaactctct atagcccaga gtcactctgc cctccttcag ccaagccagc accccgaaaa     6300

gaagaacaaa ttggtcatca aagaaaagga aaaagaaagc cagagagaga gggacagcgc     6360

cgagggggga gagggcaaca ccggtccgaa ggaaacactg ccagatgcct tgaaggccaa     6420

agagaagaaa gagttggcac cagggggtgg ttctgagcct tccatgctcc ctccacgcat     6480

tgcttcagat gccagaggga acgccaccaa ggccctgctg gagaactttg gctttgagtt     6540

ggtcatccag tataatgaga acaagcagaa ggtgcagaaa aagaatggga agactgacca     6600

gggagagaac ctggaaaagc tcgagtgtga ctcctgcggc aagttgtttt ccaacatctt     6660

gattttaaag agtcatcaag agcacgttca tcagaattac tttcctttca aacagctcga     6720

gaggtttgcc aaacagtaca gagaccacta cgataaactg tacccactga ggccccagac     6780

cccagagcca ccaccacctc cccctccacc ccctccaccc ccacttccgg cagcgccgcc     6840

tcagccggcg tccacaccag ccatccccgc atcagcccca cccatcacct cacctacaat     6900

tgcaccggcc cagccatcag tgccgctcac ccagctctcc atgccgatgg agctgcccat     6960

cttctcgccg ctgatgatgc agacgatgcc gctgcagacc ttgccggctc agctaccccc     7020

gcagctggga cctgtggagc ctctgcctgc ggacctggcc caactctacc agcatcagct     7080

caatccaacc ctgctccagc agcagaacaa gaggcctcgc accaggatca cagatgatca     7140

gctccgagtc ttgcggcaat attttgacat taacaactcc cccagtgaag agcaaataaa     7200

agagatggca gacaagtccg ggttgcccca gaaagtgatc aagcactggt tcaggaacac     7260

tctcttcaaa gagaggcagc gtaacaagga ctccccttac aacttcagta atcctcctat     7320

caccagcctg gaggagctca agattgactc ccggccccct tcgccggaac ctccaaagca     7380

ggagtactgg ggaagcaaga ggtcttcaag aacaaggttt acggactacc agctgagggt     7440

cttacaggac ttcttcgatg ccaatgctta cccaaaggat gatgaatttg agcaactctc     7500

taatttactg aaccttccaa cccgagtgat agtggtgtgg tttcagaatg cccgacagaa     7560

ggccaggaag aattatgaga atcagggaga gggcaaagat ggagagcggc gtgagcttac     7620

aaatgataga tacattcgaa caagcaactt gaactaccag tgcaaaaaat gtagcctggt     7680

gtttcagcgc atctttgatc tcatcaagca ccagaagaag ctgtgttaca aggatgagga     7740

tgaggagggg caggacgaca gccaaaatga ggattccatg gatgccatgg aaatcctgac     7800

gcctaccagc tcatcctgca gtaccccgat gccctcacag gcttacagcg ccccagcacc     7860

atcagccaat aatacagctt cctccgcttt cttgcagctt acagcggagg ctgaggaact     7920

ggccaccttc aattcaaaaa cagaggcagg cgatgagaaa ccaaagctgg cggaagctcc     7980

cagtgcacag ccaaaccaaa cccaagaaaa gcaaggacaa ccaaagccag agctgcagca     8040

gcaagagcag cccgagcaga agaccaacac tccccagcag aagctccccc agctggtgtc     8100

cctgccttcg ttgccacagc ctcctccaca agcgccccct ccacagtgcc ccttacccca     8160

gtcgagcccc agtccttccc agctctccca cctgcccctc aagcccctcc acacatcaac     8220

tcctcaacag ctcgcaaacc tacctcctca gctaatcccc taccagtgtg accagtgtaa     8280

gttggcattt ccgtcatttg agcactggca ggagcatcag cagctccact tcctgagcgc     8340

gcagaaccag ttcatccacc cccagttttt ggacaggtcc ctggatatgc ctttcatgct     8400

ctttgatccc agtaacccac tcctggccag ccagctgctc tctggggcca tacctcagat     8460

tccagcaagc tcagccactt ctccttcaac tccaacctcc acaatgaaca ctctcaagag     8520

gaagctggag gaaaaggcca gtgcaagccc tggcgaaaac gacagtggga caggaggaga     8580

agagcctcag agagacaagc gtttgagaac aaccatcaca ccggaacaac tagaaattct     8640

ctaccagaag tatctactgg attccaatcc gactcgaaag atgttggatc acattgcaca     8700

cgaggtgggc ttgaagaaac gtgtggtaca agtctggttt cagaacaccc gagctcggga     8760

aaggaaagga cagttccggg ctgtaggccc agcgcaggcc cacaggagat gccctttttg     8820

cagagcgctc ttcaaagcca agactgctct tgaggctcat atccggtccc gtcactggca     8880

tgaagccaag agagctggct acaacctaac tctgtctgcg atgctcttag actgtgatgg     8940

gggactccag atgaaaggag atatttttga cggaactagc ttttcccacc tacccccaag     9000

cagtagtgat ggtcagggtg tccccctctc acctgtgagt aaaaccatgg aattgtcacc     9060

cagaactctt ctaagccctt cctccattaa ggtggaaggg attgaagact ttgaaagccc     9120

ctccatgtcc tcagttaatc taaactttga ccaaactaag ctggacaacg atgactgttc     9180

ctctgtcaac acagcaatca cagataccac aactggagac gagggcaacg cagataacga     9240

cagtgcaacg ggaatagcaa ctgaaaccaa atcctcttct gcacccaacg aagggttgac     9300

caaagcggcc atgatggcaa tgtctgagta tgaagatcgg ttgtcatctg gtctggtcag     9360

cccggccccg agcttttata gcaaggaata tgacaatgaa ggtacagtgg actacagtga     9420

aacctcaagc cttgcagatc cctgctcccc gagtcctggt gcgagtggat ctgcaggcaa     9480

atctggtgac agcggagatc ggcctgggca gaaacgtttt cgcactcaaa tgaccaatct     9540

gcagctgaag gtcctcaagt catgctttaa tgactacagg acacccacta tgctagaatg     9600

tgaggtcctg ggcaatgaca ttggactgcc aaagagagtc gttcaggtct ggttccagaa     9660

tgcccgggca aaagaaaaga agtccaagtt aagcatggcc aagcattttg gtataaacca     9720

aacgagttat gagggaccca aaacagagtg cactttgtgt ggcatcaagt acagcgctcg     9780

gctgtctgta cgtgaccata tcttttccca acagcatatc tccaaagtta aagacaccat     9840

tggaagccag ctggacaagg agaaagaata ctttgaccca gccaccgtac gtcagttgat     9900

ggctcaacaa gagttggacc ggattaaaaa ggccaacgag gtccttggac tggcagctca     9960

gcagcaaggg atgtttgaca acacccctct tcaggccctt aaccttccta cagcatatcc    10020

agcgctccag ggcattcctc ctgtgttgct cccgggcctc aacagcccct ccttgccagg    10080

ctttactcca tccaacacag ctttaacgtc tcctaagccg aacttgatgg gtctgcccag    10140

cacaactgtt ccttcccctg gcctccccac ttctggatta ccaaataaac cgtcctcagc    10200

gtcgctgagc tccccaaccc cagcacaagc cacgatggcg atgggccctc agcaaccccc    10260

ccagcagcag cagcagcagc agcaaccaca ggtgcagcag cctcccccgc cgccagcagc    10320

ccagccgcca cccacaccac agctcccact gcaacagcag cagcaacgca aggacaaaga    10380

cagtgagaaa gtaaaggaga aggaaaaggc acacaaaggg aaaggggaac ccctgcctgt    10440

ccccaagaag gagaaaggag aggcccccac ggcaactgca gccacgatct cagccccgct    10500

gcccaccatg gagtatgcgg tagaccctgc acagctgcag gccctgcagg ccgcgttgac    10560

ttcggacccc acagcattgc tcacaagcca gttccttcct tactttgtac caggcttttc    10620

tccttattat gctccccaga tccctggcgc cctgcagagc gggtacctgc agcctatgta    10680

tggcatggaa ggcctgttcc cctacagccc tgcactgtcg caggccctga tggggctgtc    10740

cccaggctcc ctactgcagc agtaccagca ataccagcag agtctgcagg aggcaattca    10800

gcagcagcag cagcggcaac tacagcagca gcagcagcaa aaagtgcagc agcagcagcc    10860

caaagcaagc caaaccccag tcccccccgg ggctccttcc ccagacaaag accctgccaa    10920

agaatccccc aaaccagaag aacagaaaaa caccccccgt gaggtgtccc ccctcctgcc    10980

gaaactccct gaagagccag aagcagaaag caaaagtgcg gactccctct acgacccctt    11040

cattgttcca aaggtgcagt acaagttggt ctgccgcaag tgccaggcgg gcttcagcga    11100

cgaggaggca gcgaggagcc acctgaagtc cctctgcttc ttcggccagt ctgtggtgaa    11160

cctgcaagag atggtgcttc acgtccccac cggcggcggc ggcggtggca gtggcggcgg    11220

cggcggcggt ggcggcggcg gcggcggcgg cggctcgtac cactgcctgg cgtgcgagag    11280

cgcgctctgt ggggaggaag ctctgagtca acatctcgag tcggccttgc acaaacacag    11340

aacaatcacg agagcagcaa gaaacgccaa agagcaccct agtttattac ctcactctgc    11400

ctgcttcccc gatcctagca ccgcatctac ctcgcagtct gccgctcact caaacgacag    11460

cccccctccc ccgtcggccg ccgccccctc ctccgcttcc ccccacgcct ccaggaagtc    11520

ttggccgcaa gtggtctccc gggcttcggc agcgaagccc ccttcttttc ctcctctctc    11580

ctcatcttca acggttacct caagttcatg cagcacctca ggggttcagc cctcgatgcc    11640

aacagacgac tattcggagg agtctgacac ggatctcagc caaaagtccg acggaccggc    11700

gagcccggtg gagggtccca aagaccccag ctgccccaag gacagtggtc tgaccagtgt    11760

aggaacggac accttcagat tgtaagcttt gaagatgaac aatacaaaca aatgaattta    11820

aatacaaaaa ttaataacaa accaatttca aaaatagact aactgcaatt ccaaagcttc    11880

taaccaaaaa acaaaaaaaa aaaaaaaaag aaaaaaaaga aaaagcgtgg gttgttttcc    11940

catataccta tctatgccgg tgattttaca ttcttgtctt tttcttttct tttaatatta    12000

aaaaaaaaaa aaaagcccta accctgttac attgtgtcct tttgaaggta ctattggtct    12060

gggaaacaga agtccgcagg gcctccctaa tgtctttgga gcttaaaccc cttgtatatt    12120

tgcccctttt caataaacgc cccacgctga tagcacagag gagcccggca tgcactgtat    12180

gggaaagcag tccaccttgt tacagtttta aatttcttgc tatcttagca ttcagatacc    12240

aatggcttgc taaaagaaaa aaagaaatgt aatgtctttt tattctcagg tcaatcgctc    12300

acactttgtt ttcagaatca ttgttttata tattattgtt ttttcagttt tttttttttt    12360

ttttgttcca gaaaagattt tttgttttgt taacttaaaa atgggcagaa agtattcaag    12420

aaaaacaatg tgaactgctt tagctttctg gggattttta aggatagctt ttctgctgaa    12480

gccaatttca aggggaaaag ttaagcactc ccactttcaa aaaaaaaaaa aaataataac    12540

ccacacacac aaagagtgtt gaggacttgt agcttaaaaa aaataagttt taaaaactga    12600

ctttctgtat ttatgataga tatgaccatt tttggtgttg agtagattgt tgcattggaa    12660

atgaactgaa gcagtatggt agatttaaaa ggaaaaaaaa aaaaaaacct tttgtgtaca    12720

tttagctttt tgtatggtcc agctgacagc tcctcatttg atgttgtctt gttcattcct    12780

agcagatgat agattgcaat ccgttgattc gcctaagctt ttctcccctt gtcccttaat    12840

tccactttct ctttcttgtc ccttaattcc actttctctt tccttctccc acctcccgtc    12900

ctataatctc ccacttaagg tagctgcctt catttcttag agggagctgc agaattattt    12960

tataaaacta aagaaagaat ttcaagggat tctaggggtc attaggatcc tcacagatta    13020

tttttggttg gggagttgaa actttttaaa ggcatataat tctagttacc tgtgtctgtt    13080

agctttgtgc atttattttt tatttatcct tcttttggct tttttttctt tgtacccctt    13140

cttttcctcc ttgtttggta ggagcttcaa atattctttt tttttctata ctaaaggatt    13200

tgtttccatt tgtgtaattg gctgtgtact tttcttttct aaaaaaagtt tttggttagg    13260

gatttggttt ttggttttgt gtttgttttt tctttcctct ctcagaaaaa aaaatttcat    13320

gctttaaata aaatccaaag acacaccctt tcactgctga tgcagaaaaa agggaaaggg    13380

ttcttgttac ttgagaattt gtttctgatt taaacaaaca agacttagtt taataaaaga    13440

aagagaaaaa caaaagattc ccaggttgtt atgtgcttct tctgcaagca gagaggcaaa    13500

tgttaatgac aattccatat accaaaagac acatttttta cttcaaagtt ttgtccttgt    13560

gttaggcagt ctgagcagcg agtgatccag agcgcagcca acaaagcagc agatagcagt    13620

gtacagaaag caaaaaagga actgtatgtg aggcacttgt ttctgttaat atccatattc    13680

ctgttaacac acaccctttc tcatgtaaaa agaaaaataa ataaatggtc tgaactttga    13740

aaactttgtg ctgctaaaac atagattttg gagacaaata aatagatgct ttgctgtttc    13800

actttcatag ctaaacatca acagaaacca tctccccttg cccccaaagt gtgaaatcct    13860

tcttcccttc gttttcttcc ttatgtttca aaagggaact ttgaagactg tgaatacagg    13920

ttccattggt cacctttcgg gcttctttcc ccagtgctga agccactcat cgactttgca    13980

aaagactgga gcattccaag atctgaaaat ggattttttt tctttttttc ttttttagcc    14040

gggactattt tatttttatg aatttgtttt tagtttaatg aaatagtaga tcctgaaatg    14100

ttgtacatat ttctaactag gctgatgcac agtgcaaatt ccttttttaa ttgttttttt    14160

taagtagaaa tactaaagaa agaataccat ctaactattc ataccagtat ccagttgtag    14220

cataaggtgt caaaagcaag tacgcaaaac atttactgtt ttaacaagct atttcctttt    14280

aacaagaaat cttgtatttc ttcctgtgtt tgagatgaac atttttaaat tttaaagttg    14340

tacagttttt tgttttccat tattttatct tgtttgtaac tctatgaaat atatatatat    14400

atattttttg ccatttaact gttgtatgtt actctgtgtc tgtaccatat agaaaaaaaa    14460

ttgtttttgt ttttggttct ctatgtgata tcagttaaca atgtaacact agctttacct    14520

gtcaaattct gctaggtctt ctctgaaaac gttgttttta aaaatgatat tgcttggtaa    14580

tagtgcaatt tctatccttt tccctccccc ctcaactttt aagttctttt ctttataatt    14640

ttgctgcccc ctccctgatg gtttgggttt ttgtttttgt ttttgttttt ttttttcatg    14700

gagctactat gccatcctcc ctctgtgagg cagagtgact gtcagtgttt tgttatgcca    14760

tgccttgagc tgtgggtgtt tggcgacaat aaggtggttg aatagattgg ctgagcacac    14820

ttccacccac ctagtgttct cagaggggtt atgtgattgt ttcaacctgg agtgggttgc    14880

acccttaatg ctttcctctg caactaaacc gcccacatat atgttcattg aaaaaagtaa    14940

gaataattct cagcactaac ccagaagtag caaagcagtc agtgatggtg aacattagag    15000

gtcaaacatg agttagatgt ttgtgggctg acagccatcg tggctatgac cagtactatt    15060

tacaaagcat gaattcacta caatgctcaa ctgtttgttt agctttatct cacttgggga    15120

atttattcct gtctgctgca ttgtaggtag ctgggtagga tatatttcca cttgcttttt    15180

aaattagttc ttcacctcca ttgacactcg ttttttggtt ttctccctat agtgtgggtt    15240

ggtgctagac accagtctga cccacagaat gggagttatt tcatccatct ttcctccatc    15300

cttccaaaaa ccacatatct acacaaggaa aaatttaata catctaggaa tttttttttt    15360

aattacaagc tatttaaaga gatgaatgtg gccaaagttt tacacaattg aaaataaagt    15420

aaaacagacg gcatgtgttt aaacctgagt ttatcaggca tggcaggaag ttgcaggaga    15480

gagaggcagt gacccaagcc agtgcacttg atgttcatgg acatatattt tttttaaata    15540

ataaattaaa acattttaaa tagaagcata aattgagttg tttgttggcg ctgagatact    15600

gcccactgtg aaacaaagct ttgactagtt ttttgtttgt ttactttctt caggggggag    15660

gggggcaagt ttgggtagga aagaaagcat aaatgaacgt gaccctgagg tgaagaggta    15720

tatgaacagc ctttgcaatg tacaaaaaga aaaaaaaaca aaaaacaaca aaaaaaatag    15780

agcaagtgaa accaaaaatg atgttcttgg tgtttttcta taatgtagtc ttgttagctt    15840

ttttgttact gtaacaatgc tgatctcgaa ctgtaccaaa atacatggag actaacaaac    15900

agaaccacat ggaactttca aactgaaaaa aaaatttgtc acaaaaactt tgttgtcata    15960

gttaagttga ttgtagatgg taattgaata tactcctttg aaaatatttc atcaagtatg    16020

tttcctgctc attgtgatac attaaaaaaa aaatatgagc aaaa                     16064


<210>  2226
<211>  7049
<212>  DNA
<213>  homo sapiens

<400>  2226
gtgctgaggg ggcgcggcgc ggaggggcgc ggagcggcgc ggagccgggc ggctcggggc       60

ccagagagag ccgcggccgg gagctcgcgg gctcctgaca acctcctccc ctcggcggac      120

gacgaccacg gcgactaggg cgccggtcat ggcggagcaa caaacccggc gcggacccta      180

ggcaccaccg catggagcgg gacgaaccgc cgcctagcgg agggggaggc ggcgggggct      240

cggcggggtt cctggagcct cccgccgcgc tccctccgcc gccgcgcaac ggtttctgtc      300

aggatgaatt ggcagagctt gacccaggca ctaatgatcg ggctgaacaa cgaacctgtc      360

tcatttgtgg ggaccgcgct acaggcttgc actatgggat catctcctgt gagggctgca      420

aagggttttt caagcggagc atttgcaaca aacgggtata tcgatgcagt cgtgacaaga      480

actgtgtcat gtctcggaag cagaggaaca ggtgccagta ctgccgcctg ctcaaatgcc      540

tccagatggg gatgaaccgg aaggctatca gagaagatgg catgcctgga ggccggaata      600

agagcattgg gccagtccag atatcggaag aagaaatcga aaggatcatg tctgggcagg      660

agtttgagga agaggccaat cactggagca accatggtga tagtgaccac agttcccctg      720

ggaacagggc ttcggagagc aaccagccct caccaggctc cacactgtct tccaggtctg      780

tggaactgaa tggattcatg gccttcaggg aacagtacat gggaatgtct gtgcctccac      840

attaccaata tataccgcac ctttttagct attctggcca ctcaccactt ctgccccaac      900

aagctcgcag cctggatccc cagtcataca gtctgattca ccagctgtta tcagccgagg      960

acctggaacc attgggcacg cccatgttga ttgaagatgg atacgctgtg acacaggcag     1020

aactatttgc cctgctttgc cgcctggccg acgagctgct ctttaggcag attgcctgga     1080

tcaagaaact gcctttcttc tgcgagctct caatcaagga ttacacgtgc ctcttgagct     1140

ctacgtggca ggagctaatc ctgctgtctt ccctcaccgt ttacagcaag cagatctttg     1200

gggaactggc tgatgtcact gccaagtact cgccctccga tgaagaacta cacagattta     1260

gtgatgaagg gatggaggtg atcgagcggc tcatctacct ctatcacaag ttccatcagc     1320

taaaggtcag caacgaggag tatgcttgca tgaaagcaat taacttccta aatcaagata     1380

tcaggggtct gaccagtgcc tcacagctgg aacaattgaa taaacgatac tggtacattt     1440

gccaggattt tactgaatat aaatacacac atcagccgaa ccgctttcct gatctcatga     1500

tgtgcttacc tgagattcga tatattgcag gaaagatggt gaatgtgccc ctggagcagc     1560

tgcccctcct ctttaaggtg gtgctgcatt cctgcaagac cagtgtgggc aaggaatgac     1620

ctgttccagg cgccctcctc aggccaacca cagcgtcttg ggtgggcagg acaggctctg     1680

gagggaaaag ccagagagac caagatggag gctgtggagc agcatttccc gttgcctcca     1740

tagcaagaag agtttttgtt tgtttgtctg tttttttaac ctcatttttc tatatattta     1800

tttcacgaca gagttgaatg tatggccttc aacatgatgc acatgctttt gtgtgaatgc     1860

agccaatgca ttttcttaca gtttacagaa tgtgaagatg tttaatgtta cagtgttgtc     1920

attgtttaga aatagttctt ttgtattttg agggagaggg tgggatgggg ctaagatgac     1980

tatttccata atgttgacaa agatgactac ctcaatggaa atggggggtg tggccatccc     2040

tactttttcc acattttctc agcagactca tacatttgtc tgtcagagag caaattgcct     2100

tttttagcca cagaattgcc agataaaacg gcacactgta agggggcaaa gtgttgttag     2160

gagattcact aagcaaggtt ggtgagacgg caacagggta ggaggtgagg attgagccac     2220

gtcctttcct tggaaagcgt gaaaattaag agagtagggc acagtgacca tatttaaggc     2280

aggtgtcctt ccacccaaca agtcctaagg gcagaagaat ttctgttctc acaccttgct     2340

gcccccctta cccctgcacc accatcattg tctaccactg cgaactttcc atctaggcaa     2400

agtcctggca atcacttgat ccacaggact cgcctcccag ctccctcggg gcccccagct     2460

acctagtttc cttacctgga tctcctgagg cccaccttcc tccttcccac tcccttacac     2520

atttgacttc ctattggccc tttgaaaaac cagctgagca gaatgccatg ttctgaagcc     2580

tggtgcccac tactgattta ttctcctttc accttgtttt cttcaaaggg tagtagggca     2640

aggccagact gcaaaaagaa tagacactcc ccttttgaaa tctgttcctc tcccctcccc     2700

ttcctaccgc accctcaggt ctaaatccga aaacttcagg cttttttaaa caatgagaag     2760

gaccattcac ctgtctgctg accagaaatg ttgcccctaa gttcttctcc aagttctcct     2820

tttctctcca gagtgagacc agttttcctc agggacccag gacacaaagc ccaaggccca     2880

gagtggctca gctgcccctt acttcagcag tggactggcc agccaaggcc tggagggctg     2940

gagccagaag cacctggaag ggaagggggg ctttaaacta cctcaggttc ctaatggccc     3000

ggctgctacc tctgcagaca tggcctggac tccttgacct ctcactacct gccccacctt     3060

atcccaggac gtgttcctta ccctcttgac tttggccagc gctacaccag gtctgtcttt     3120

gaactctttc aggtgcttgt cctgcctaca cccaggtatc tttcacagcc agtgtggcaa     3180

gcagaccact tagttggctg catgcctggg taggttggaa gggcccacgg caccttcttc     3240

tgcctattta gtcaaaggct gtttgctgtc tcctcaactc aacctagtaa agctacccag     3300

gagggcacca cgtcgtgtgc atactgggta gtccatgtct gattgtaatt gtttctttct     3360

ggtgaaatgt tacgggtacc agcagagtga tgattttggc ccttgatgga tctaaaactc     3420

ggaacattac tcctcaatgc cgtttcccca gttgctctga gaaggaagag acatgttcct     3480

caggaaaagc tccagctagc atgtttttca cgtcagtggg aagattcttg tgtgttcgtg     3540

tgtatctgtt tatttctaag ttcacgatac ttgttcccct gaattttatt taaccaacta     3600

gatcacattc tttggccaca ggtcagactc tgagctgctt tcctccagat cgggaaggag     3660

acacatatca cagatgcctt ctctaagaca gctcctgtgt acagcatcgt tctttgctga     3720

ggcctctatc tgtccaatta ttatttttga aattgctttt caaattaaac attttacccg     3780

ttgtgttggg tgtcaaaaga aattgctctc tgatgaggca agaacatgtc tctccaacaa     3840

cgtagtattg aacagagcaa gttgttaatt tgtggagtag gggaaaggtt ctgcaagttg     3900

ccattgtaca aatccagttt tacaaatgtt tgcagcagat tccacagaac aaagagccca     3960

ttcattgccg agagccctgc agaatctcag agcaaagtgg ctgtgtgttc cgagccggag     4020

cctgacctgt ggaccgtctt taatgtcttc tgcaccagtc cttttatgac gtgggctttt     4080

tttaaacagg gtaaagtgaa tgtgttgcat tgcaaactca ggtattatga ggagaaggta     4140

ggagtgtagc tagcagcgtg gagacattag gtcagccact agatgtattt gtgaatttgg     4200

tttgaaggac acggagaaag gttggagggg aggtttggtg tgtttgtttt ttgctttctt     4260

ccccataatg tttggttaac aggtagcctt tttgcgagtg gaaggagaga aaagttgtgc     4320

atgttttctc taatttctct ttctgccctc tctctgatcc ccaaccacca aaagcactca     4380

ctttgagtga ggattttttt tttttttttt tttttttttt ttgaggcgga gtctcgctct     4440

gtcgctcagg ctggagtgca gtggtgcgat cttggctcac tgcaagctcc gcctcccggg     4500

ttcatgccat tctcctgcct cagcctcctg agtagctggg actacaggcg cccgccacca     4560

cacccggcta actttttttg tatttttagt agaaacattg tttcaccacg ttagccagga     4620

tggtctccat ctcctgacct cgtgatccgc ctgcctcggc ctcccaaagt gctgggatta     4680

caggcgtgag ccactgcacc cagccgagtg agaattttta tgccataaaa atacgactct     4740

gaaagctaca tggaaaagga gaatcccacc tccttgcact acattgaaac atgcaagcct     4800

ttccctccct ctcctttttg atgttttctt gtcccaagac aaaagtttgg catcttggaa     4860

cttattcatg ctctctggct gcctttgtag acttttggag tcctttgcaa ggtttggtgg     4920

tctcgtcgtt aatctggaga aattccccag aatctgtctc aaagcgctca acctggctca     4980

gaggacaccc agcccctatg ccccactcac aagagaggtg ggcaagcccc cagggatagg     5040

aggaagtaag caggatcctc cctgtcctgt ttcccagaac cagagcaagg aatggggaat     5100

cctaagggtt tctgtggcat cactgaatgt cacccactcc acatcaacct gcctctcacc     5160

tgccaccctt tttcagggag gtgagtacct gccatggtca ctgttaccag atccttaaaa     5220

tcctgggctc tgagctaggt gcattgctct gttacccatt tcctacattt gtttgtttgt     5280

tcttgatttc ctgggggaat gggactgatg gagacagaca aacccactgt gggcagcatc     5340

taagccatgt ccaaggttgg tcgaattaag ggaaccctgg cctctcagca ggacagaaag     5400

ctgagctgtg gttccaggcc ctcctctctg ggcccctggt gtgtatcttt tttccttgtt     5460

gcttttgaaa tttttgcaat tattttaaga atccagtctt tcagaccagc ccttttatta     5520

agctttgaat ttttaattga tttttttaaa gtaaaaaaaa aaaaaaccca aaaaacaaac     5580

aaaatttaac aaaaaaatcc gctactctta ctcccctgcc tccccctacc ccagcccatg     5640

agagttccct tgcactcccc tctgcctttg caactgatca tcctcccttt ctccttggct     5700

tgaagcatct atgtccagta tctgtgaaat gatgttttat ctgtgtgtca ggatgagaaa     5760

cggcagtcat tccaccaagt gttggaaact ggttagcctg gagacaaggg tttctggggc     5820

cacagctcag ggatgtgtat ttaattacag gatccccaga aactcctctc taggctgcca     5880

cagcaacatt ttttctgggc ttgggagcca tacctgaact gtttcctcca aggcgggaac     5940

tccagagagc ctgccaagtc tggagcaagc tggggcttct gctttggcca gacctgggcc     6000

accatgagac ttgaaggctt ctagctgtcc tacgacacga gccacggtgg ccctgcctct     6060

ccccgctcat agaagcctgg tccctctgtc tagcccagtt cccatctagc atccgtcttc     6120

tgggcctgaa gccctaaatg gaccacagcc tgcacaggaa tcaactgtag gctcaaaggg     6180

aggcggtgag taaggtcaga gcctgctcca agcccaagaa caaaagttgt gttatgggtg     6240

gaggctagtc ccccagatct agccctgccg tctttgccct ttaatgacca ttgttttctt     6300

tctctaaaat gtcttgtaat aggtgataat gttgttgatt caaatttcca tgaaaaagaa     6360

aaaaaaaact acctcttaag cgacatcctg gtcgattcct ctctgaggaa tcctgtggga     6420

aaagaatact gtagctcctg ctctgtttac atgtttctgt cgggaaagaa gccccgcctg     6480

ccctggggtg ttggtgtttt tgtctgtgtt gccatcccag gtctgccata ggggctggtg     6540

gctgcattgt gatgtctggg ctgtgtctgg ggattccttc ccacctaccc agccagggac     6600

tagtcacccc cctgaagagg cctccatttc cttcctgtgc tccagggcat agggagcacc     6660

actcccacag acaccacctt taagggctct agtggcacac acatccacga gcctaccccc     6720

aggttacctg ccctaggtcc acctccaccc acagtcctgt gtgtaggaat cgaggaaacg     6780

ggatgtccct gagcccttgt ctccaaaggg ccggccaagg gctgcccgcc agcctgactc     6840

catcaaccct ccatgaccaa atgatagctg gcgggctctg caggctaccc aggccctctg     6900

ctacctccca ccctgccagc tggcaaggga tgggccctgt tctgtgaatt gactacctgt     6960

ggaaatgtga ccaattagtg tgaaatgcat gtttagcaag tgttaggtac tgtatttgaa     7020

ccaataaatg tgaatccttc tgcacatgg                                       7049


<210>  2227
<211>  7064
<212>  DNA
<213>  homo sapiens

<400>  2227
gtgctgaggg ggcgcggcgc ggaggggcgc ggagcggcgc ggagccgggc ggctcggggc       60

ccagagagag ccgcggccgg gagctcgcgg gctcctgaca acctcctccc ctcggcggac      120

gacgaccacg gcgactaggg cgccggtcat ggcggagcaa caaacccggc gcggacccta      180

ggcaccaccg catggagcgg gacgaaccgc cgcctagcgg agggggaggc ggcgggggct      240

cggcggggtt cctggagcct cccgccgcgc tccctccgcc gccgcgcaac ggtttctgtc      300

aggatgaatt ggcagagctt gacccaggca ctatttctgt ttcagatgat cgggctgaac      360

aacgaacctg tctcatttgt ggggaccgcg ctacaggctt gcactatggg atcatctcct      420

gtgagggctg caaagggttt ttcaagcgga gcatttgcaa caaacgggta tatcgatgca      480

gtcgtgacaa gaactgtgtc atgtctcgga agcagaggaa caggtgccag tactgccgcc      540

tgctcaaatg cctccagatg gggatgaacc ggaaggctat cagagaagat ggcatgcctg      600

gaggccggaa taagagcatt gggccagtcc agatatcgga agaagaaatc gaaaggatca      660

tgtctgggca ggagtttgag gaagaggcca atcactggag caaccatggt gatagtgacc      720

acagttcccc tgggaacagg gcttcggaga gcaaccagcc ctcaccaggc tccacactgt      780

cttccagtag gtctgtggaa ctgaatggat tcatggcctt cagggaacag tacatgggaa      840

tgtctgtgcc tccacattac caatatatac cgcacctttt tagctattct ggccactcac      900

cacttctgcc ccaacaagct cgcagcctgg atccccagtc atacagtctg attcaccagc      960

tgttatcagc cgaggacctg gaaccattgg gcacgcccat gttgattgaa gatggatacg     1020

ctgtgacaca ggcagaacta tttgccctgc tttgccgcct ggccgacgag ctgctcttta     1080

ggcagattgc ctggatcaag aaactgcctt tcttctgcga gctctcaatc aaggattaca     1140

cgtgcctctt gagctctacg tggcaggagc taatcctgct gtcttccctc accgtttaca     1200

gcaagcagat ctttggggaa ctggctgatg tcactgccaa gtactcgccc tccgatgaag     1260

aactacacag atttagtgat gaagggatgg aggtgatcga gcggctcatc tacctctatc     1320

acaagttcca tcagctaaag gtcagcaacg aggagtatgc ttgcatgaaa gcaattaact     1380

tcctaaatca agatatcagg ggtctgacca gtgcctcaca gctggaacaa ttgaataaac     1440

gatactggta catttgccag gattttactg aatataaata cacacatcag ccgaaccgct     1500

ttcctgatct catgatgtgc ttacctgaga ttcgatatat tgcaggaaag atggtgaatg     1560

tgcccctgga gcagctgccc ctcctcttta aggtggtgct gcattcctgc aagaccagtg     1620

tgggcaagga atgacctgtt ccaggcgccc tcctcaggcc aaccacagcg tcttgggtgg     1680

gcaggacagg ctctggaggg aaaagccaga gagaccaaga tggaggctgt ggagcagcat     1740

ttcccgttgc ctccatagca agaagagttt ttgtttgttt gtctgttttt ttaacctcat     1800

ttttctatat atttatttca cgacagagtt gaatgtatgg ccttcaacat gatgcacatg     1860

cttttgtgtg aatgcagcca atgcattttc ttacagttta cagaatgtga agatgtttaa     1920

tgttacagtg ttgtcattgt ttagaaatag ttcttttgta ttttgaggga gagggtggga     1980

tggggctaag atgactattt ccataatgtt gacaaagatg actacctcaa tggaaatggg     2040

gggtgtggcc atccctactt tttccacatt ttctcagcag actcatacat ttgtctgtca     2100

gagagcaaat tgcctttttt agccacagaa ttgccagata aaacggcaca ctgtaagggg     2160

gcaaagtgtt gttaggagat tcactaagca aggttggtga gacggcaaca gggtaggagg     2220

tgaggattga gccacgtcct ttccttggaa agcgtgaaaa ttaagagagt agggcacagt     2280

gaccatattt aaggcaggtg tccttccacc caacaagtcc taagggcaga agaatttctg     2340

ttctcacacc ttgctgcccc ccttacccct gcaccaccat cattgtctac cactgcgaac     2400

tttccatcta ggcaaagtcc tggcaatcac ttgatccaca ggactcgcct cccagctccc     2460

tcggggcccc cagctaccta gtttccttac ctggatctcc tgaggcccac cttcctcctt     2520

cccactccct tacacatttg acttcctatt ggccctttga aaaaccagct gagcagaatg     2580

ccatgttctg aagcctggtg cccactactg atttattctc ctttcacctt gttttcttca     2640

aagggtagta gggcaaggcc agactgcaaa aagaatagac actccccttt tgaaatctgt     2700

tcctctcccc tccccttcct accgcaccct caggtctaaa tccgaaaact tcaggctttt     2760

ttaaacaatg agaaggacca ttcacctgtc tgctgaccag aaatgttgcc cctaagttct     2820

tctccaagtt ctccttttct ctccagagtg agaccagttt tcctcaggga cccaggacac     2880

aaagcccaag gcccagagtg gctcagctgc cccttacttc agcagtggac tggccagcca     2940

aggcctggag ggctggagcc agaagcacct ggaagggaag gggggcttta aactacctca     3000

ggttcctaat ggcccggctg ctacctctgc agacatggcc tggactcctt gacctctcac     3060

tacctgcccc accttatccc aggacgtgtt ccttaccctc ttgactttgg ccagcgctac     3120

accaggtctg tctttgaact ctttcaggtg cttgtcctgc ctacacccag gtatctttca     3180

cagccagtgt ggcaagcaga ccacttagtt ggctgcatgc ctgggtaggt tggaagggcc     3240

cacggcacct tcttctgcct atttagtcaa aggctgtttg ctgtctcctc aactcaacct     3300

agtaaagcta cccaggaggg caccacgtcg tgtgcatact gggtagtcca tgtctgattg     3360

taattgtttc tttctggtga aatgttacgg gtaccagcag agtgatgatt ttggcccttg     3420

atggatctaa aactcggaac attactcctc aatgccgttt ccccagttgc tctgagaagg     3480

aagagacatg ttcctcagga aaagctccag ctagcatgtt tttcacgtca gtgggaagat     3540

tcttgtgtgt tcgtgtgtat ctgtttattt ctaagttcac gatacttgtt cccctgaatt     3600

ttatttaacc aactagatca cattctttgg ccacaggtca gactctgagc tgctttcctc     3660

cagatcggga aggagacaca tatcacagat gccttctcta agacagctcc tgtgtacagc     3720

atcgttcttt gctgaggcct ctatctgtcc aattattatt tttgaaattg cttttcaaat     3780

taaacatttt acccgttgtg ttgggtgtca aaagaaattg ctctctgatg aggcaagaac     3840

atgtctctcc aacaacgtag tattgaacag agcaagttgt taatttgtgg agtaggggaa     3900

aggttctgca agttgccatt gtacaaatcc agttttacaa atgtttgcag cagattccac     3960

agaacaaaga gcccattcat tgccgagagc cctgcagaat ctcagagcaa agtggctgtg     4020

tgttccgagc cggagcctga cctgtggacc gtctttaatg tcttctgcac cagtcctttt     4080

atgacgtggg ctttttttaa acagggtaaa gtgaatgtgt tgcattgcaa actcaggtat     4140

tatgaggaga aggtaggagt gtagctagca gcgtggagac attaggtcag ccactagatg     4200

tatttgtgaa tttggtttga aggacacgga gaaaggttgg aggggaggtt tggtgtgttt     4260

gttttttgct ttcttcccca taatgtttgg ttaacaggta gcctttttgc gagtggaagg     4320

agagaaaagt tgtgcatgtt ttctctaatt tctctttctg ccctctctct gatccccaac     4380

caccaaaagc actcactttg agtgaggatt tttttttttt tttttttttt tttttttgag     4440

gcggagtctc gctctgtcgc tcaggctgga gtgcagtggt gcgatcttgg ctcactgcaa     4500

gctccgcctc ccgggttcat gccattctcc tgcctcagcc tcctgagtag ctgggactac     4560

aggcgcccgc caccacaccc ggctaacttt ttttgtattt ttagtagaaa cattgtttca     4620

ccacgttagc caggatggtc tccatctcct gacctcgtga tccgcctgcc tcggcctccc     4680

aaagtgctgg gattacaggc gtgagccact gcacccagcc gagtgagaat ttttatgcca     4740

taaaaatacg actctgaaag ctacatggaa aaggagaatc ccacctcctt gcactacatt     4800

gaaacatgca agcctttccc tccctctcct ttttgatgtt ttcttgtccc aagacaaaag     4860

tttggcatct tggaacttat tcatgctctc tggctgcctt tgtagacttt tggagtcctt     4920

tgcaaggttt ggtggtctcg tcgttaatct ggagaaattc cccagaatct gtctcaaagc     4980

gctcaacctg gctcagagga cacccagccc ctatgcccca ctcacaagag aggtgggcaa     5040

gcccccaggg ataggaggaa gtaagcagga tcctccctgt cctgtttccc agaaccagag     5100

caaggaatgg ggaatcctaa gggtttctgt ggcatcactg aatgtcaccc actccacatc     5160

aacctgcctc tcacctgcca ccctttttca gggaggtgag tacctgccat ggtcactgtt     5220

accagatcct taaaatcctg ggctctgagc taggtgcatt gctctgttac ccatttccta     5280

catttgtttg tttgttcttg atttcctggg ggaatgggac tgatggagac agacaaaccc     5340

actgtgggca gcatctaagc catgtccaag gttggtcgaa ttaagggaac cctggcctct     5400

cagcaggaca gaaagctgag ctgtggttcc aggccctcct ctctgggccc ctggtgtgta     5460

tcttttttcc ttgttgcttt tgaaattttt gcaattattt taagaatcca gtctttcaga     5520

ccagcccttt tattaagctt tgaattttta attgattttt ttaaagtaaa aaaaaaaaaa     5580

acccaaaaaa caaacaaaat ttaacaaaaa aatccgctac tcttactccc ctgcctcccc     5640

ctaccccagc ccatgagagt tcccttgcac tcccctctgc ctttgcaact gatcatcctc     5700

cctttctcct tggcttgaag catctatgtc cagtatctgt gaaatgatgt tttatctgtg     5760

tgtcaggatg agaaacggca gtcattccac caagtgttgg aaactggtta gcctggagac     5820

aagggtttct ggggccacag ctcagggatg tgtatttaat tacaggatcc ccagaaactc     5880

ctctctaggc tgccacagca acattttttc tgggcttggg agccatacct gaactgtttc     5940

ctccaaggcg ggaactccag agagcctgcc aagtctggag caagctgggg cttctgcttt     6000

ggccagacct gggccaccat gagacttgaa ggcttctagc tgtcctacga cacgagccac     6060

ggtggccctg cctctccccg ctcatagaag cctggtccct ctgtctagcc cagttcccat     6120

ctagcatccg tcttctgggc ctgaagccct aaatggacca cagcctgcac aggaatcaac     6180

tgtaggctca aagggaggcg gtgagtaagg tcagagcctg ctccaagccc aagaacaaaa     6240

gttgtgttat gggtggaggc tagtccccca gatctagccc tgccgtcttt gccctttaat     6300

gaccattgtt ttctttctct aaaatgtctt gtaataggtg ataatgttgt tgattcaaat     6360

ttccatgaaa aagaaaaaaa aaactacctc ttaagcgaca tcctggtcga ttcctctctg     6420

aggaatcctg tgggaaaaga atactgtagc tcctgctctg tttacatgtt tctgtcggga     6480

aagaagcccc gcctgccctg gggtgttggt gtttttgtct gtgttgccat cccaggtctg     6540

ccataggggc tggtggctgc attgtgatgt ctgggctgtg tctggggatt ccttcccacc     6600

tacccagcca gggactagtc acccccctga agaggcctcc atttccttcc tgtgctccag     6660

ggcataggga gcaccactcc cacagacacc acctttaagg gctctagtgg cacacacatc     6720

cacgagccta cccccaggtt acctgcccta ggtccacctc cacccacagt cctgtgtgta     6780

ggaatcgagg aaacgggatg tccctgagcc cttgtctcca aagggccggc caagggctgc     6840

ccgccagcct gactccatca accctccatg accaaatgat agctggcggg ctctgcaggc     6900

tacccaggcc ctctgctacc tcccaccctg ccagctggca agggatgggc cctgttctgt     6960

gaattgacta cctgtggaaa tgtgaccaat tagtgtgaaa tgcatgttta gcaagtgtta     7020

ggtactgtat ttgaaccaat aaatgtgaat ccttctgcac atgg                      7064


<210>  2228
<211>  2184
<212>  DNA
<213>  homo sapiens

<400>  2228
tattcttcca aatggaaact gctaattttt gaagcagaag gttgacagct tcagtaagat       60

ctcaagagag cgagaagact ggaatcaggg aaccctactc tggaaactgt cagtcccagg      120

gcactgggga gggctgaggc cgaccatgcc cagcctgctg ctgctgttca cggctgctct      180

gctgtccagc tgggctcagc ttctgacaga cgccaactcc tggtggtcat tagctttgaa      240

cccggtgcag agacccgaga tgtttatcat cggtgcccag cccgtgtgca gtcagcttcc      300

cgggctctcc cctggccaga ggaagctgtg ccaattgtac caggagcaca tggcctacat      360

aggggaggga gccaagactg gcatcaagga atgccagcac cagttccggc agcggcggtg      420

gaattgcagc acagcggaca acgcatctgt ctttgggaga gtcatgcaga taggcagccg      480

agagaccgcc ttcacccacg cggtgagcgc cgcgggcgtg gtcaacgcca tcagccgggc      540

ctgccgcgag ggcgagctct ccacctgcgg ctgcagccgg acggcgcggc ccaaggacct      600

gccccgggac tggctgtggg gcggctgtgg ggacaacgtg gagtacggct accgcttcgc      660

caaggagttt gtggatgccc gggagcgaga gaagaacttt gccaaaggat cagaggagca      720

gggccgggtg ctcatgaacc tgcaaaacaa cgaggccggt cgcagggctg tgtataagat      780

ggcagacgta gcctgcaaat gccacggcgt ctcggggtcc tgcagcctca agacctgctg      840

gctgcagctg gccgagttcc gcaaggtcgg ggaccggctg aaggagaagt acgacagcgc      900

ggccgccatg cgcgtcaccc gcaagggccg gctggagctg gtcaacagcc gcttcaccca      960

gcccaccccg gaggacctgg tctatgtgga ccccagcccc gactactgcc tgcgcaacga     1020

gagcacgggc tccctgggca cgcagggccg cctctgcaac aagacctcgg agggcatgga     1080

tggctgtgag ctcatgtgct gcgggcgtgg ctacaaccag ttcaagagcg tgcaggtgga     1140

gcgctgccac tgcaagttcc actggtgctg cttcgtcagg tgtaagaagt gcacggagat     1200

cgtggaccag tacatctgta aatagcccgg agggcctgct cccggccccc ctgcactctg     1260

cctcacaaag gtctatatta tataaatcta tataaatcta ttttatattt gtataagtaa     1320

atgggtgggt gctatacaat ggaaagatga aaatggaaag gaagagctta tttaagagac     1380

gctggagatc tctgaggagt ggactttgct ggttctctcc tcttggtggg tgggagacag     1440

ggctttttct ctccctctgg cgaggactct caggatgtag ggacttggaa atatttactg     1500

tctgtccacc acggcctgga ggagggaggt tgtggttgga tggaggagat gatcttgtct     1560

ggaagtctag agtctttgtt ggttagagga ctgcctgtga tcctggccac taggccaaga     1620

ggccctatga aggtggcggg aactcagctt caacctcgat gtcttcaggg tcttgtccag     1680

aatgtagatg ggttccgtaa gaggcctggt gctctcttac tctttcatcc acgtgcactt     1740

gtgcggcatc tgcagtttac aggaacggct ccttccctaa aatgagaagt ccaaggtcat     1800

ctctggccca gtgaccacag agagatctgc acctcccgga cttcaggcct gcctttccag     1860

cgagaattct tcatcctcca cggttcacta gctcctacct gaagaggaaa gggggccatt     1920

tgacctgaca tgtcaggaaa gccctaaact gaatgtttgc gcctgggctg cagaagccag     1980

ggtgcatgac caggctgcgt ggacgttata ctgtcttccc ccacccccgg ggaggggaag     2040

cttgagctgc tgctgtcact cctccaccga gggaggcctc acaaaccaca ggacgctgca     2100

acgggtcagg ctggcgggcc cggcgtgctc atcatctctg ccccaggtgt acggtttctc     2160

tctgacatta aatgcccttc atgg                                            2184


<210>  2229
<211>  5069
<212>  DNA
<213>  homo sapiens

<400>  2229
gaggcggagg cggccccggg ctcgggcggc tgggatggag cagaagagcg cggagcaccg       60

gagggcacgc agctgacgga gctgcgctgc gttcgcctcg tttgcctcgc gccctccact      120

ggagctgttc gcgcctcccg gctcccaccg cagcccaccc ggcagaggag tcgctaccag      180

cgcccagtgc gctctgtcag tccgcaaact ccttgccgcc cgccccgggc tgggcaccaa      240

ataccaggct accatggtct acaagactct cttcgctctt tgcatcttaa ctgcaggatg      300

gagggtacag agtctgccta catcagctcc tttgtctgtt tctcttccga caaacattgt      360

accaccgacc accatctgga ctagctctcc acaaaacact gatgcagaca ctgcctcccc      420

atccaacggc actcacaaca actcggtgct cccagttaca gcatcagccc caacatctct      480

gcttcctaag aacatttcca tagagtccag agaagaggag atcaccagcc caggttcgaa      540

ttgggaaggc acaaacacag acccctcacc ttctgggttc tcgtcaacaa gcggtggagt      600

ccacttaaca accacgttgg aggaacacag ctcgggcact cctgaagcag gcgtggcagc      660

tacactgtcg cagtccgctg ctgagcctcc cacactcatc tcccctcaag ctccagcctc      720

atcaccctca tccctatcaa cctcaccacc tgaggtcttt tctgcctccg ttactaccaa      780

ccatagctcc actgtgacca gcacccaacc cactggagct ccaactgcac cagagtcccc      840

gacagaggag tccagctctg accacacacc cacttcacat gccacagctg agccagtacc      900

ccaggagaaa acacccccaa caactgtgtc aggcaaagtg atgtgtgagc tcatagacat      960

ggagaccacc accacctttc ccagggtgat catgcaggaa gtagaacatg cattaagttc     1020

aggcagcatc gccgccatta ccgtgacagt cattgccgtg gtgctgctgg tgtttggagt     1080

tgcagcctac ctaaaaatca ggcattcctc ctatggaaga cttttggacg accatgacta     1140

cgggtcctgg ggaaactaca acaaccctct gtacgatgac tcctaacaat ggaatatggc     1200

ctgggatgag gattaactgt tctttattta taagtgctta tccagtagaa ttaataagta     1260

cctgatgcgc attgaacgac aatcttaagc cctgttttgt tggtatggtt gtttttgttt     1320

tcctccctct cctctggctg ctacaacttc ccctttctgg tacaagaaga accattcttt     1380

aaaggtgagt ggaggctgat ttgcagctga agtgggccag ccttgcacca gccaggccag     1440

accaccatgg tgaaggcttc tttccccact gcaggaccca ctttgagaag gaccgaggag     1500

gaggatttgg gttgttttgt taggggttac tttcagggga acatttcatt tgtgttattt     1560

cttaaacttc tatttaggaa attacattaa gtattaatga ggggaaagga aatgagctct     1620

acgaggattt caccctgcat gggagagagc agggttttct cagattcctt tttaatctct     1680

atttatctgg ttgtttctga caggatgctg cctgcttggc tctacaagct ggaaagcagc     1740

ttcttagctg cctaattaat gaaagatgaa aataggaagt gccctggagg gggccagcag     1800

gtcacggggc agaatctctc aggttgctgt gggatctcag tgtgccccta cctgttctcc     1860

cctccaggcc acctgtctct gtaaaggatg tctgctctgt tcaaaaggca gctgggatcc     1920

cagcccacaa gtgatcagca gagttgcatt tccaaagaaa aaggctatga gatgagctga     1980

gttatagaga gaaagggaga ggcatgtacg gtgtggggaa gtggaagaga agctggcggg     2040

ggagaaggag gctaacctgc actgagtact tcattaggac aagtgagaat cagctattga     2100

taatggccag agatatccac agcttggagg agcccagaga ccgtttgctt tatacccaca     2160

cagcaactgg tccactgctt tactgtctgt tggataatgg ctgtaaaatg tttaaaaaca     2220

aaacaaaaca aaaaagaggc actagtctat ctgcaattac tcaacgaggc attttcatag     2280

gaaacagact atgattaatc catttattct tcccacacac ttaccttact aagtctttgc     2340

tttaataaat gagcaaccct gggtatagtc ttaaaattct gcacaataaa ttttgagaaa     2400

gaattgttcc tctttgtagg tatctgtgta ttgcaatcat tctcaaccag gaggtgattt     2460

tgccccctga ctccacccca gggacattca aaaatgtctg gtgacagttt tcattgtcat     2520

gacttggggg tgctactaga agccaggaat gctgccaaac attctaccat gcacagcaca     2580

acctacaaca gcaaagaatc atccacccca aaatatcagt agtgccgaga ttgagaaacc     2640

ctgatttatc acaatgccca ctgtgacaga acaagacact cacagattag tgatacgttt     2700

tatttttaac aaaatgaaat gatgtgttaa gtttttattt ccaaagtgtt tagtttattg     2760

gctgatgggt tgttcttggt atgcatggtg acctttttat ttctgtgtgc ttcctagaga     2820

gctttatttc atggcgacaa ctctgtcttc ttgtaacagc tgatattagc aagcagcatc     2880

ttatgtcctg atttcatata gtagaaaaca aacattgggt ccgacttcaa aatgtgttgt     2940

attgtcctac agtgtcataa agaacctgaa aatgaacttt tgtttctaaa gttggacctt     3000

gctgccatga ctgtttagtt tacagaaact tgaccccggc tcatcctgtc tctggctgtg     3060

gcccggcaaa gcactgaaaa cccctctggt ctcagagaca gtaggggcag tgccactttc     3120

tacaacctgc caacccacac actggagtaa ttctgaaaaa aattattcct aaactctcta     3180

agtgtggacg gagaatgagc aagccccaga agtattttac aaccagagtg ggtaatgagg     3240

agggggctta ctggaatcgt catatctctg aatattgaaa acaacaacta aaaaagtgga     3300

ccttctcaga aaaaaagggc agcaaatgac caagggcgcc ccttctggcc gtgcttggct     3360

tgagtaactg tctctctttc cccaccccca tcacagggct ttcagtttgg caaaggaaaa     3420

gcagataaaa acagaacatt ccatatgttt ctttctccat cggccaaaaa cattttgaca     3480

caatgtttgt gaaacacctt tggagaggtg cacttctgaa tgctgcctct gccgtaaatc     3540

ctggggcaag ggatcagcct cttcccagga accatcgcct tctataaacc gtgaactcaa     3600

gcaggcattt tttttttctt accgaaaggc tgctattgtg caagggcaca taatgggtct     3660

gttgctctta ttggcttcca aatgtgcatg gcaaagagag agatgtgggc ctagagcaga     3720

tatattcagc aaggtgacag cttcccataa caattctaac acttcttatc ttatgtgaga     3780

ataaaatatt taagggttga accttatttt gccaaatgta tcttttctgc ttttgaattg     3840

ggcagaagat tttagcaact atattctaca aatgttactt ataacacaca cacacacatc     3900

tgaaatatat gccgaaaatt gacgtctttg acctcaggga gagcacctgt ccaggtctgc     3960

ctaaaggaaa tggctccagt gggtctaaac aaccacatcc tatccatgga taggtctagt     4020

cataacactt tagagagaat gtcagagcag gagggaggca agccgcctct tctcggccat     4080

cgactgcaga tgatgaaaga gcgggattca actttgtttt cttttcctgt ggccccagtg     4140

aaacctcctg ccctccctgc acgtctgtgt cttcatttct aaaatggggg tgatgctttc     4200

atattgacct caccccatac tacctcacag atgtgttgtg aggattaata aaattatgtc     4260

tatggtattt tcagtttctg gagaaaaata cttatagaca gtttaactat tacatagata     4320

tataagtgat ctcagtttct tgtttgctgt gatactaatg tgttgtttta acttattcca     4380

taaaatgaca gttgtgtcct agccacatca gacagctatc taagctctgg actacccctt     4440

tgtgcagctg aatcactgca gggttgacca tgcctggtgc cacagccatg gtttccattt     4500

ctagatgaaa ggatggccta ggacataggt ctcaaagact cttggatcag aatcaggaga     4560

ttagggaaaa caggatggat acctgagcac taacagcagt agacgtagac ctctgtcctt     4620

taccatctga ggtcttctgg attctttgtg gggttaattt tgatttgatg tcatctgttt     4680

gcccttcatc ttgcttgcaa gtgtgcatgg ttcaatccct cacatccagg aaatgaattt     4740

tgcaattggg ccagatgcta atttgcacgt tgattcacct tctttgcctt taagcctttt     4800

ttttcttttt tttttttttg gcaaatgaat gtaccatttc aactttgatt ttaatagtgc     4860

tagttgatat tggtaataat gctaaccaag agatcaatgc cagatttttc tcttggggta     4920

agttagctga agtcatttaa agatggaaag gtgggaaaat tctttgatat ttgatgtcat     4980

tgtatccaca tttgttgtaa gacatattgc ataccaatta taattatatc aattaaagtt     5040

gataaaagct tccaaaaaaa aaaaaaaaa                                       5069


<210>  2230
<211>  3390
<212>  DNA
<213>  homo sapiens

<400>  2230
ctgcctcagg aagcttggct tcccctccca tggggaagtg ctggaatcca ctcttgcctg       60

accctcccat aagaaacaag ggaaattcct ttacgtgagc cgccttgctc agaacaaagc      120

ttggcgtgtt tcttattcct catcaatctg acaaaatggg tatttatttg tgcctctcaa      180

gcgtgtggct tggacatgat gttccgcatc gtggaagtgg ccgtgcacca agtggaatat      240

ctgttactat agtaacagtt cctttttatt gataccagaa taaacaggaa tgcaaaggct      300

gtctcacttg ttggcacatt tcagcagcct ccgttcccag gggtttaaga accgccctct      360

agaggcagcc ctccttgcta gtctgggact tcccggtgga gtgaggaacc cagcaacacg      420

ctcctgactt cccttcccaa ggactcgacc tgagaaccgc catgtactcg gagatccaga      480

gggagcgggc agacattggg ggcctgatgg cccggccaga atacagagag tggaatccgg      540

agctcatcaa gcccaagaag ctgctgaacc ccgtgaaggc ctctcggagt caccaggagc      600

tccaccggga gctgctcatg aaccacagaa ggggccttgg tgtggacagc aagccagagc      660

tgcagcgtgt cctagagcac cgccggcgga accagctcat caagaagaag aaggaggagc      720

tggaagccaa gcggctgcag tgcccctttg agcaggagct gctgagacgg cagcagaggc      780

tgaaccagct ggaaaaacca ccagagaagg aagaggatca cgcccccgag tttattaaag      840

tcagggaaaa cctgcggaga attgccacac tgaccagcga agagagagag ctgtagggcc      900

agctgccggg ctcaggccac tgcccaccct ggcctggaca gcctccttca gcccttctgt      960

acctggcagc cctgggcccc aggccctggg acgtctgtga tgttcccacc tgcttctgta     1020

gaaatgtgtc accccagagg gcctggctct ccctgggagg ctggggcccc taagctccta     1080

ggttttcctt ccaagcaccc agccctcctg ctccaagagg gataacctgc acccctccct     1140

gcaaggggtt cagagcccag cacaggagct ttctctggca gaattgagga ggaagaggtg     1200

gccctctgac ttgacaagcc ttctgttctg cccaggcctt cccaccagga atctccgagg     1260

ctccccaggg ccccgcttct ccgtacaccc cagctcctag gtctcagaga actcccccac     1320

ctgtggtttt acctgcagcc agcagagctt agcttcaagg acacctgcct tcaaagccac     1380

tgaggggagg aagggcaggg cagactgcag atggccttgt tgctggcatc ccggccaggt     1440

gggcggggac taacaaagac agctgtttag ggtcttctcc cctcacccat gctttcatca     1500

tcccctccgc acagcctccc cgtccaggcc ttctaaccac acctacccag ggctgccgca     1560

ttcctgcact cagaagtctg cagcggtgcc tcacaaactt gattgtgcat aaaaatcact     1620

ggggatcttg ttaatacagc ttctaactca atagatctgg gagatcctgc atttctaaca     1680

agctcccagg taaggcggag gctgctggtg tgaggaccat gctgtgagca gcagggcgag     1740

agtgcccagg gctgatatat attggaaata tcacccctga agccatcgct ggcccccacc     1800

tcctgtggac tgatgcccca gggattccca ccccacttct gcaaccccag gtatccttca     1860

ttatccaccc catcccagac tcccacccca gggattgccc gtgaagactt tggcctagca     1920

aattgtgttg gttatgtgag tgttgtttta atcagagatg tacatgattg ccaatctgca     1980

tttcttacca gtgtgaccac actgttacga tgcaattcta gccaaaaaaa aaaaaaaaaa     2040

aaaaaaaatt tttttttttt actttttcct agtcttatgg aaagcaaata tacaatgatt     2100

ttcagtaggc ttctggaata gaaacagtgg tttgaagacc ccactgccac ctttatggac     2160

tggccccttt gagtctgaat ccccggcctc tgtcacctga gacccaaccc ctagctgggc     2220

caactccagt gaattcaccc atttttcttc ttcagaaggc ctttcctgtg tgagacccac     2280

atattttaac cttttgctcc tatcccattt ttaaagaatt agagaataaa ccaggcctgt     2340

ttcttttccc ctgaaatccc tgcctctggc ttcctaaacc catcatctaa ggtgacagag     2400

cagtgctgga atagcatctc ctttcacttt cccaaaactg ccacagatag ctgccactgg     2460

catgctcttt gattcctgga agcaaacgtg ggactgtcgg aggaaaggga ttgttctggt     2520

cttactcata actgggtggt ttgagggtga ctgaagtcgt gcttttcctg tgtgtgctgc     2580

cagcacaggg ctgtaaatgc agatattgcg cctgtgtgcg tgtgtataag tcaagctcca     2640

agaggctcct gaatgtgact ggcgtgctga gaatgtgttt acgctgttta atgtctgcca     2700

ggtgagggtt acactgaaga tgcacaatcc ctaaaataaa gatcaccact tccccaaaga     2760

agcagccctc gggtccatgt gttgttcaga catgtgaaga gaagcaagac agagggtctc     2820

agatggacga gggctctcca agggaatgcc tggggattca cccagtggtc cccagaggtg     2880

ctccatggag gcaacaagtc attccatgaa gccccagagg tagaagggac ctcaagcacc     2940

acgccctcca gggcagccgt gcagacgacc ttggttcact tttcaggggt cgtcccaact     3000

ctgtatctcc agccactcca actgtggagg ctgtaaatcc agattttcac tgttccagtc     3060

tcctttgcag cttaggatgg ctatgtgatc aggtgtggcc aatgaaattg aagaggaagt     3120

ctacctgggc ttctgggaaa gcttttccaa taaaagacac aggcatggct aacacctccc     3180

tgggcctctt cttcctacct tgattgaggg tgtgatgcct ggagccacag cagccacttt     3240

gctaccatga caaaaaggcc aagagaatca cagagtcatt gaccctatca ttatttcacc     3300

aagccaatac cagccgccat ccttctccag aattcttgta aataaaataa atccctcttt     3360

gtttaaacca ttaaaaaaaa aaaaaaaaaa                                      3390


<210>  2231
<211>  4007
<212>  DNA
<213>  homo sapiens

<400>  2231
gttggaggtg gagtagttca gaatcaactg acgcagccgg gaattgagct ttgcaaagcc       60

acttgcaagg aagggaagca tctgcccaac cctcccccac cgcgcgccct ggatcctctg      120

cctgccccct cccccgtgac gtcaccctag tcctgtcccg gggagcctgc aaagcctctc      180

agattcaaac tgctagacgc actgctgcca ccgccaccga attggaaacg cgcgcccagg      240

ctccgtcgtc gccttcgccc gccgaccggg ccagccggct ctccgacctc cctacagaat      300

cgcaccccag tccctccctg gcagctcggc ttccctcagc tccaactctt ctcttccgct      360

cctgcctcct gtcggatttt taatttctgc gcacccccag tcaaattaaa tcaaccaaca      420

aaaagcaggg catcccccct ggaagcagcg tcttatttta ccttgttctc ccacttcctg      480

aagatgctaa actcctggtg gactgcagag gagagggatt cagtcttctc ctgatgtgtt      540

tgcctgtagg tacctgagtt gacaccgaag gtgcctaaag atgctgagcg gcgtttggtt      600

cctcagtgtg ttaaccgtgg ccgggatctt acagacagag agtcgcaaaa ctgccaaaga      660

catttgcaag atccgctgtc tgtgcgaaga aaaggaaaac gtactgaata tcaactgtga      720

gaacaaagga tttacaacag ttagcctgct ccagcccccc cagtatcgaa tctatcagct      780

ttttctcaat ggaaacctct tgacaagact gtatccaaac gaatttgtca attactccaa      840

cgcggtgact cttcacctag gtaacaacgg gttacaggag atccgaacgg gggcattcag      900

tggcctgaaa actctcaaaa gactgcatct caacaacaac aagcttgaga tattgaggga      960

ggacaccttc ctaggcctgg agagcctgga gtatctccag gccgactaca attacatcag     1020

tgccatcgag gctggggcat tcagcaaact taacaagctc aaagtgctca tcctgaatga     1080

caaccttctg ctttcactgc ccagcaatgt gttccgcttt gtcctgctga cccacttaga     1140

cctcaggggg aataggctaa aagtaatgcc ttttgctggc gtccttgaac atattggagg     1200

gatcatggag attcagctgg aggaaaatcc atggaattgc acttgtgact tacttcctct     1260

caaggcctgg ctagacacca taactgtttt tgtgggagag attgtctgtg agactccctt     1320

taggttgcat gggaaagacg tgacccagct gaccaggcaa gacctctgtc ccagaaaaag     1380

tgccagtgat tccagtcaga ggggcagcca tgctgacacc cacgtccaaa ggctgtcacc     1440

tacaatgaat cctgctctca acccaaccag ggctccgaaa gccagccggc cgcccaaaat     1500

gagaaatcgt ccaactcctc gagtgactgt gtcaaaggac aggcaaagtt ttggacccat     1560

catggtgtac cagaccaagt ctcctgtgcc tctcacctgt cccagcagct gtgtctgcac     1620

ctctcagagc tcagacaatg gtctgaatgt aaactgccaa gaaaggaagt tcactaatat     1680

ctctgacctg cagcccaaac cgaccagtcc aaagaaactc tacctaacag ggaactatct     1740

tcaaactgtc tataagaatg acctcttaga atacagttct ttggacttac tgcacttagg     1800

aaacaacagg attgcagtca ttcaggaagg tgcctttaca aacctgacca gtttacgcag     1860

actttatctg aatggcaatt accttgaagt gctgtaccct tctatgtttg atggactgca     1920

gagcttgcaa tatctctatt tagagtataa tgtcattaag gaaattaagc ctctgacctt     1980

tgatgctttg attaacctac agctactgtt tctgaacaac aaccttcttc ggtccttacc     2040

tgataatata tttgggggga cggccctaac caggctgaat ctgagaaaca accatttttc     2100

tcacctgccc gtgaaagggg ttctggatca gctcccggct ttcatccaga tagatctgca     2160

ggagaacccc tgggactgta cctgtgacat catggggctg aaagactgga cagaacatgc     2220

caattcccct gtcatcatta atgaggtgac ttgcgaatct cctgctaagc atgcagggga     2280

gatactaaaa tttctgggga gggaggctat ctgtccagac agcccaaact tgtcagatgg     2340

aaccgtcttg tcaatgaatc acaatacaga cacacctcgg tcgcttagtg tgtctcctag     2400

ttcctatcct gaactacaca ctgaagttcc actgtctgtc ttaattctgg gattgcttgt     2460

tgttttcatc ttatctgtct gttttggggc tggtttattc gtctttgtct tgaaacgccg     2520

aaagggagtg ccgagcgttc ccaggaatac caacaactta gacgtaagct cctttcaatt     2580

acagtatggg tcttacaaca ctgagactca cgataaaaca gacggccatg tctacaacta     2640

tatcccccca cctgtgggtc agatgtgcca aaaccccatc tacatgcaga aggaaggaga     2700

cccagtagcc tattaccgaa acctgcaaga gttcagctat agcaacctgg aggagaaaaa     2760

agaagagcca gccacacctg cttacacaat aagtgccact gagctgctag aaaagcaggc     2820

cacaccaaga gagcctgagc tgctgtatca aaatattgct gagcgagtca aggaacttcc     2880

cagcgcaggc ctagtccact ataacttttg taccttacct aaaaggcagt ttgccccttc     2940

ctatgaatct cgacgccaaa accaagacag aatcaataaa accgttttat atggaactcc     3000

caggaaatgc tttgtggggc agtcaaaacc caaccaccct ttactgcaag ctaagccgca     3060

atcagaaccg gactacctcg aagttctgga aaaacaaact gcaatcagtc agctgtgaag     3120

ggaaatcatt tacaacccta aggcatcaga ggatgctgct ccgaactgtt ggaaacaagg     3180

acattagctt ttgtgtttgt ttttgttctc cctttcccag tgttaatggg ggactttgaa     3240

aatgtttggg agataggatg aagtcatgat tttgcttttg caagttttcc tttaaattat     3300

ttctctctcg ctctcctccc ctcctttttt tttttttttt ttttttcttt ttcccttctc     3360

ttcttaggaa ccatcagtgg acatgaatgt ttctacaatg catttcttca tagattttgt     3420

ttatggtttt gtttcttttt tcttctttgt ttttcagtgt gggagtggga agaggagatt     3480

atagtgactg aagaaagaat aggcaaactt ttcaaatgaa aatggatatt tagtgtattt     3540

tgtagaagat ctccaaagat cttttgtgac tacaacttct tttgtaaata atgatatatg     3600

gtatttccat cgtcagttac cgagtatagc cactgggtat cactactttg tgttaaagtg     3660

ccttcgcact ttaagtacat tacttaaatg ttgcttttag ctttgataaa ttgaaaatat     3720

tttaatgtgt tgtatttttg aaattgaaaa cactgtaaaa tagattgatg tgtcagctat     3780

attaagtcaa cgtacagttt gcttgagtta tagaaaccag cctgtcatca aatgattcta     3840

gttctaggac tttgtaggct taactataaa atatttcctt tcctctgggt ttaagtgatt     3900

ttatttaagt caactaaggg gatttaacag tggactagag gtaataagcc acctcagtca     3960

ggattaataa ttcattaata aaatatattt aacccaaaaa aaaaaaa                   4007


<210>  2232
<211>  1219
<212>  DNA
<213>  homo sapiens

<400>  2232
cggaccctcc cgcggccgac tggaggcccg gagcaggggc ggagtttccg gcggcagcgc       60

cactcgggcg tcgggtgacg ctaggcggac ggaccatcat gtgacacgga agtagctccg      120

aacaggaaga ggacgaaaaa aataaccgtc cgcgacgccg agacaaaccg gacccgcaac      180

caccatgaac agcaaaggtc aatatccaac acagccaacc taccctgtgc agcctcctgg      240

gaatccagta taccctcaga ccttgcatct tcctcaggct ccaccctata ccgatgctcc      300

acctgcctac tcagagctct atcgtccgag ctttgtgcac ccaggggctg ccacagtccc      360

caccatgtca gccgcatttc ctggagcctc tctgtatctt cccatggccc agtctgtggc      420

tgttgggcct ttaggttcca caatccccat ggcttattat ccagtcggtc ccatctatcc      480

acctggctcc acagtgctgg tggaaggagg gtatgatgca ggtgccagat ttggagctgg      540

ggctactgct ggcaacattc ctgtaaaaga agatcaagat cacgaccgag agcagggtga      600

ggaagacaac ggtgataaca acttggaaag gagagggaaa atgtagagat gtttcaggat      660

tgaggatgtc tcagtagttc ctggagtcat ctgatttagt cactgttttc gtaaagatcc      720

tcttgttttc attaactagt gtccacttcc atccaaaccc atgttccccc accaacccca      780

atttccatgg cacataatag ctggagtctc ctggtgctta agctaaggac acatgctttt      840

gatttctgac aaaactgaac tgcctcccaa accagttcct gattcttaaa gaaacgggaa      900

ggagggaaca ggaaatggct tatcctaaca ggaagtggtt tatctgatcc tccccctctt      960

cctcacccac tcaaccaacc acatatatcc tcgtccctac ccacgtactc aagtgtaacg     1020

tccgtatgca tatctatttg cggccacctc ccaacctgtc atttactggt agtgcctctg     1080

acagaagcct ccgagtcttt tatggctgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg     1140

taatataact tacaagccag agtgagccca ttaatggatt tggtcaggct ccctctggag     1200

agagatgccc ttgatccag                                                  1219


<210>  2233
<211>  2543
<212>  DNA
<213>  homo sapiens

<400>  2233
gaggatgggt aacatgcccg aaggcacaga gagtgtcttg gtctgtccgg acgcgtctgt       60

agagttacag gaagagaagg gccgccctcc agagggccgg gagcgcccca gcgcgggtcc      120

ggggtcgagg taaaatgtcg gttccaggac cttaccaggc ggccactggg ccttcctcag      180

caccatccgc acctccatcc tatgaagaga cagtggctgt taacagttat taccccacac      240

ctccagctcc catgcctggg ccaactacgg ggcttgtgac ggggcctgat gggaagggca      300

tgaatcctcc ttcgtattat acccagccag cgcccatccc caataacaat ccaattaccg      360

tgcagacggt ctacgtgcag caccccatca cctttttgga ccgccctatc caaatgtgtt      420

gtccttcctg caacaagatg atcgtgagtc agctgtccta taacgccggt gctctgacct      480

ggctgtcctg cgggagcctg tgcctgctgg ggtgcatagc gggctgctgc ttcatcccct      540

tctgcgtgga tgccctgcag gacgtggacc attactgtcc caactgcaga gctctcctgg      600

gcacctacaa gcgtttgtag gactcagcca gacgtggagg gagccgggtg ccgcaggaag      660

tcctttccac ctctcatcca gcttcacgcc tggtggaggt tctgccctgg tggtctcacc      720

tctccagggg gcccaccttc atgtcttctt ttggggggaa tacgtcgcaa aactaacaaa      780

tctccaaacc ccagaaattg ctgcttggag tcgtgcatag gacttgcaaa gacattcccc      840

ttgagtgtca gttccacggt ttcctgcctc cctgagaccc tgagtcctgc catctaactg      900

tgatcattgc cctatccgaa tatcttcctg tgatctgcca tcagtggctc ttttttcctg      960

cttccatggg cctttctggt ggcagtctca aactgagaag ccacagttgc cttatttttg     1020

aggctgttct gcccagagct cggctgaacc agcctttagt gcctaccatt atcttatccg     1080

tctcttcccg tccctgatga caaagatctt gccttacaga ctttacaggc ttggctttga     1140

gattctgtaa ctgcagactt cattagcaca cagattcact ttaatttctt aatttttttt     1200

ttaaatacaa ggagggggct attaacaccc agtacagaca tatccacaag gtcgtaaatg     1260

catgctagaa aaatagggct ggatcttatc actgccctgt ctccccttgt ttctctgtgc     1320

cagatcttca gtgccccttt ccatacaggg atttttttct catagagtaa ttatatgaac     1380

agtttttatg acctcctttt ggtctgaaat acttttgaac agaatttctt ttttttaaaa     1440

aaaaacagag atggggtctt actatgttgc ccaggctggt gtcgaactcc tgggctcaag     1500

cgatccttct gccttggcct cccgaagtgc tgggattgca ggcataagct accatgctgg     1560

gcctgaacat aatttcaaga ggaggattta taaaaccatt ttctgtaatc aaatgattgg     1620

tgtcattttc ccatttgcca atgtagtctc acttaaaaaa aaaaaaaaga aaaagaaatg     1680

gataatttca tctactgcct ttacttgggg ttaatgtgat tcttaaacac cttcatcatg     1740

gaactctcag agtggggtcc gttttggttt cctggtggtg ggttttgaaa gataagggaa     1800

agcacatttt gagcatgtct gggtaccatg gtgcggatgc ttgggaacca gaactgtttc     1860

agaggaatct aaagtctgat tttagttttc agagacacag cttgttgtaa aacatgagaa     1920

gacatgattt ctaggactca agcagcaagc caggattcta ggttggctgc tgtgtcatct     1980

ttgaagtcaa gacaaagctg ggctcgacct tcaagggtcc tcgttttgat aatacttcag     2040

aatagggaac tcatgtgaat actactatgt agaaataaaa cctagacctt gagcgaacat     2100

ctgtatattg gttgaaaacg atagtggtaa ccattgatcc cccttcattt gatgtttgga     2160

aaattccagt aattatcatt tttgcaacga atatggatac cacatagtac tttggtgtta     2220

cctgcttttg aaaaataaag tctttggttc acccggtgaa ctatttatga gttcttttgg     2280

tgtgaagaaa gggctcatgt tgcatttcca gccattgcta caaagaacct ttatttgttc     2340

agtaacggta gaaaatcctt cccgattaaa aacttcagac ttgctgaata tcctgcaatg     2400

tcaagatgac cgatgttgag ttgggtggat ttgctaacga gtcagatttg aacatgaggc     2460

tattggaacc caataggcgt cattgatggc ggcaagccat agctttcaag ttttaataaa     2520

atgcacaaaa gagaaaaaaa aaa                                             2543


<210>  2234
<211>  1273
<212>  DNA
<213>  homo sapiens

<400>  2234
ccttgagtct ccacacacac tcctcacaga gatctgtagc gtaggtacgt gacagctctg       60

cctacatctg acgtccggag tcattaacca ggaatgtatg tgtgtctgtg tgtctctctg      120

tggagtcgtc agaattcttc ataggggtta agctaaaaaa gcgaggcgag gagcccctct      180

ccaatggctc agttttgctg aataatcacg tgtgaatcga ggggcgggct tttggcaggc      240

agatcttact agtatttact accaagctct actccagatt aaccatccca gtccttctgt      300

cagtctccga tgccatcatg cagcctggtt aggagcaaag gaaaggggaa aaagaaaaac      360

gactaattca tcttttcctg atcgtcagga ccctaaagaa tggccgagcc ttgggggaac      420

gagttggcgt ccgcagctgc caggggggac ctagagcaac ttactagttt gttgcaaaat      480

aatgtaaacg tcaatgcaca aaatggattt ggaaggactg cgctgcaggt tatgaaactt      540

ggaaatcccg agattgccag gagactgcta cttagaggtg ctaatcccga tttgaaagac      600

cgaactggtt tcgctgtcat tcatgatgcg gccagagcag gtttcctgga cactttacag      660

actttgctgg agtttcaagc tgatgttaac atcgaggata atgaagggaa cctgcccttg      720

cacttggctg ccaaagaagg ccacctccgg gtggtggagt tcctggtgaa gcacacggcc      780

agcaatgtgg ggcatcggaa ccataagggg gacaccgcct gtgatttggc caggctctat      840

gggaggaatg aggttgttag cctgatgcag gcaaacgggg ctgggggagc cacaaatctt      900

caataaacgt ggggagggct cccccacgtt gcctctactt tatcaattaa ctgagtagct      960

ctcctgactt ttaatgtcat ttgttaaaat acagttctgt catatgttaa gcagctaaat     1020

tttctgaaac tgcataagtg aaaatcttac aacaggctta tgaatatatt taagcaacat     1080

ctttttaacc tgcaaaatct gttctaacat gtaattgcag ataactttga ctttcttctg     1140

aatattttat ctttccttgg cttttccctt gcttcccctt ttgccaatct caacacccaa     1200

gttgaagact ttgtttttaa aatggtttgt cctgatgctt ttgtctaatt aaaacacttt     1260

caaaacagga caa                                                        1273


<210>  2235
<211>  8051
<212>  DNA
<213>  homo sapiens

<400>  2235
gtctctccaa gggaatgaaa ggtgagggga gcgtgagtgc aggcatgatg ggaatctccg       60

tgacttgtga accaaggact gggttttgct ctggaagcct gtcctgattg cttctgtaat      120

ctggcgctat gcatccggat cttggaccct tatgtacact gctgtatgtt actcttacaa      180

ttctgtgctc ttctgtgagt tcagacttgg caccttattt tacttctgag ccgctctctg      240

ctgtccagaa acttggtgga cctgtagtac tgcattgttc tgctcaacct gtgaccactc      300

gtatctcatg gctgcataac ggaaaaacat tggatggaaa cctggaacat gttaagattc      360

atcaggggac tctgacaatt ctttctctca actcctctct tttgggttac taccagtgcc      420

ttgccaacaa tagcatcggt gccattgtga gtggccctgc gacagtatct gtggcagttc      480

ttggtgattt tggttcatcc acaaagcatg ttattacagc agaagaaaaa agtgctggtt      540

tcattggctg cagggtaccg gagagtaacc ccaaagctga ggtgcgctat aaaatccggg      600

gaaaatggct ggaacattcc acagagaatt acttaatcct tccatcagga aatcttcaga      660

ttttgaatgt atccttagag gacaagggat catacaaatg tgcagcttat aatcctgtca      720

cacatcaatt aaaagttgaa cctattggcc gaaagctcct tgtgagtcgt ccttcttcag      780

atgatgttca cattcttcac cccacccatt cacaggcatt agctgttctt tctcgtagcc      840

ctgtaacctt ggagtgtgtg gtgagtgggg tcccggctcc tcaagtgtat tggctaaagg      900

acgggcagga cattgcacca ggaagcaact ggagaaggtt gtattctcat cttgccactg      960

atagcgttga cccggcggac tccggaaact attcctgcat ggcgggaaac aagtctggag     1020

atgtaaaata tgtgacttac atggttaatg tacttgaaca tgcttccatt tctaaaggac     1080

tacaggatca gatagtgtct ctgggtgcca cagtacactt tacctgcgac gttcatggga     1140

acccagcccc caactgtacc tggtttcaca atgcacagcc tattcatcct tctgcacgac     1200

atctaactgc aggaaacgga ctgaaaatca gtggggttac tgtggaagat gttgggatgt     1260

atcagtgtgt agcagataat gggattggat ttatgcactc tactggaaga cttgaaattg     1320

aaaatgacgg tggattcaag ccagttataa ttacggcacc agtaagtgca aaggttgcag     1380

acggagactt tgttactctg tcctgcaatg ccagtgggct gccggttccg gtcattcgtt     1440

ggtatgacag ccatggattg ataaccagcc atccatctca agtcctgaga tcgaaatccc     1500

gaaaatcaca gttatcaaga cctgagggct tgaacctgga gcctgtgtac ttcgtcctgt     1560

cccaagctgg tgcaagctct ctccatattc aggctgtgac tcaggaacat gcggggaaat     1620

acatctgcga agctgcaaat gaacatggta ccacacaggc agaagcatct ctcatggttg     1680

ttccttttga aacaaataca aaagcagaga cagtcacact tcctgatgct gctcagaatg     1740

atgacagaag taagagagat ggttcagaaa ctgggttact gagctcattt ccggtgaagg     1800

tccatcccag tgcagtggaa tcagcaccag agaaaaacgc cagcggcatc tctgttcctg     1860

atgcccccat catactgagc cccccacaga cccacacacc agacacgtac aacctggtgt     1920

ggagggcagg caaggatggt gggctgccca tcaatgctta ctttgtgaag tatcgaaagc     1980

tggatgatgg ggttggcatg ctgggaagct ggcacacggt tcgagtccca ggaagtgaaa     2040

atgagctcca tttagctgag ctggagccat ctagtcttta tgaagtcttg atggtagcaa     2100

gaagcgcagc aggtgaaggc caacctgcca tgcttacctt ccgaaccagc aaagaaaaaa     2160

cagcgtcatc aaaaaacacc caggcatcct ctccacccgt gggcatccct aagtatcccg     2220

ttgtttcaga ggctgcaaac aacaattttg gagtggtact tacagattcc tctaggcaca     2280

gtggagttcc agaggcacca gatcggccta ccatctccac tgcatcagag acatcagtct     2340

atgtcacttg gattcctcgg gcaaacgggg gttctccaat cactgccttc aaagtcgaat     2400

ataaacggat gaggaccagc aattggctgg tggcagctga agacatccct ccttccaaac     2460

tttcagtgga agttcgtagt ttagaaccag gttcaacata caaatttagg gtcattgcca     2520

tcaaccatta tggtgagagt tttcggagtt cagcatctcg tccttatcaa gtggttgggt     2580

tccccaatcg cttttccagc cgtccaataa ctggacctca cattgcatac acagaggctg     2640

tcagcgatac tcagatcatg ctaaagtgga cgtacattcc atcaagtaac aataacactc     2700

ccattcaagg attttatatc tattaccgac caacagatag tgacaatgac agtgattaca     2760

agagggatgt tgtagaaggt tcaaagcagt ggcacatgat tggccacctg cagccagaaa     2820

cctcctatga cattaaaatg caatgcttca atgaaggagg agaaagtgaa tttagcaatg     2880

tgatgatctg cgagactaaa gtgaaacgtg ttcctggagc ttctgaatat cctgtcaaag     2940

acttgagtac ccctccaaat tctttgggaa gtggaggaaa tgtggggcct gcaaccagcc     3000

ctgccagaag cagtgacatg ttatatctga tcgttggctg tgtgctgggc gtcatggtcc     3060

tcattctgat ggttttcatt gcaatgtgcc tgtggaagaa tcgccagcag aataccatac     3120

aaaaatatga cccaccagga tatctctacc aaggatcaga tatgaacggg cagatggtgg     3180

actacaccac tctctcagga gcaagtcaga taaatggaaa tgttcacgga ggcttcctaa     3240

ccaatggcgg tctcagcagt ggctattccc accttcacca taaggtcccc aatgcagtca     3300

atggaattgt gaatgggagc ctaaatggag ggctttactc cgggcacagc aactctctaa     3360

ccaggacaca cgtggatttt gaacatcctc atcatctagt gaatggtggt ggaatgtaca     3420

cggccgtgcc tcagattgac cctctggagt gtgttaactg ccgaaattgt cgaaacaaca     3480

ataggtgttt caccaaaacc aacagcactt tcagcagcag ccctcctcct gtggtccctg     3540

tggtagcacc ttatcctcag gatggtttgg aaatgaagcc cctcagtcac gtgaaggtgc     3600

ctgtatgcct gacttccgca gtccctgatt gtggccagtt gccggaggag agcgtcaagg     3660

acaatgtgga accagtccct actcagcgta cctgctgtca ggacattgta aatgacgtca     3720

gctctgatgg ctcagaagat ccagcagagt tcagcagagg agacagctgt gcccattcag     3780

aaacagagat caacattgta agttggaatg ctcttatttt gccacctgtc cccgagggct     3840

gtgctgagaa gacaatgtgg tctccacctg gcattccttt agacagcccg acagaggtcc     3900

ttcagcagcc ccgggaaacc tgaggacatg caaacaacca gtcatgttcc aacttcaagc     3960

cggtaactgc acacaacagg cctgggagcg aactgtgtga aggaccttaa ttcaaatcag     4020

agaaaatcat tatttatttt tttgtagtag taatgtcata tgaatgtatc ttaaaacgtg     4080

tgccctttta tattatttat gccttaaatg ttttcttccc cattccttcc tccccctcgg     4140

taggaaacaa ccttgttttg catagtattc agtcacctgg agggcagagg ggtccttcca     4200

tgttttctaa cagctatagt gacagcaaga gctcctcatg caaaggatcc catctcttgg     4260

ctgcttcggc taggagggaa tgcaggggcc cgttgaaggt tgccaccagc tgggttttca     4320

ggtggaaaat ggtctttcaa tagtgtattc tcagactttt ttttgtttgt tttttgagat     4380

ggagtcttgc tgtcatccag gctggagtgc aatggctcga tcttggctca ctgcaacctc     4440

cgcctcccag gttcaagcaa ttctcccgcc tcagcctcct gagtagctgg gactacaggc     4500

acctgccacc acgtccagct aattgtcttg tatttttatt agagacaagg tttcaggctg     4560

gttttgaact cctgacctca agtgatccac ccgcctccgc ctcccaaagt gcgaggatta     4620

caggcgtgag ccaccacgtc tggcctgtat tatcagactt cctgagaaca ctttgaaatc     4680

aactgcagtt gtgacccatg tttataataa cagacctggc tgacggattt tacaagagtg     4740

ccttccacag aagtggtaat gtgacctgtt gactttgtat ctgcacgtgg gcacgagtga     4800

tgttcagttt gctaggcact agtcatagtg ttatggacgt ggtggagtgt aaggtcttga     4860

tgaattacgg cagtatgcag aaaaggaacc aaggccagag agacaaataa tgcctcatgt     4920

cccactgctt taaaattaca ttaatttata aaatggccac tatgggctct ttttgactgt     4980

ttctcggagt aggaacaaaa taagacatta aatggtggct tgaagagaaa gatacacatt     5040

ttcagaagaa agaaagggga gggctgcagg gagcctgtct tggcgggagc tctccagtct     5100

gttggattag cacagggaca cgcttatggt gccatgacgc cgaaactagt catcccccat     5160

ctccagcata ggcaacggcc tgcaggggtg agtgtcagaa aagacttact ttggaagaaa     5220

agggtttttt tttgtttgtt tgttttttgt ttttttttgt ttgtttgttt tgggtttttt     5280

tcctgaaatt tcctgatacc tttttcagaa tgtcaccctt gtaaataggc acctaaagcc     5340

aagttggtca gcagagctcc tgaccacggc tgcctctgcg tgacaaggac atttgcagct     5400

gcctttggaa ggctcttcac attaaaaaac aataattatg taagtgtgtt tcatagcttg     5460

agtcaagctt tcaaggatca ctgctccttt gtgcattgtg catccctttg gggaaagaaa     5520

cagaaaatta ttctctttct atagagtcaa gcaattccag cagaagtgaa gaaatgttag     5580

tttcccagaa atcgcagtgg aatagaatac aatactgtgt taaccaactt tctgtataaa     5640

tgcatcagta ttcccttaca tatgtctata tattttataa tagaactgtt agtgaaaatg     5700

tgcttgttta agctgggtca ctatgcaaga gttacttcca gtagaatgta gtgaatgtaa     5760

ttccctagtc ggatattagg gatgctgtag acccaagttc tacattccag atgtccgtgc     5820

ctatagtata ctggatttat tcttcatgtt gcttaaatgc agttagctct ggagggggat     5880

agctgcatcc cttacttctg tgactagcaa aggacaaagt cccagcgcac agaatatgaa     5940

aacataccct gtgttagcca atcaagttac agcaatgctg tcacaaaggg agttttagaa     6000

aactggggag tcattgtccg tagacagcca ttttgattta ggaaacaggt gtattagcat     6060

gagccttagg tcatgaactg cttttaaaga ttgagtttga atatgggatc tgtccacgag     6120

gaagagaaaa tggctttacc tttaggacaa tctcattgtg gactgcttta tttatattat     6180

tagtaacgct gttttaagtg ttattctttt tattgtattt tatttataaa aaatgccttt     6240

atatattgaa atatataaat atatatatat aaacacacac acacacacac acacacacat     6300

atatatatat atatataatt gcctttatat ttaggcggta tgagttctcc ctaagcgtga     6360

gttggctctg ccctgcacag gcacccaaac agtcctacct aatgtcactt caccaggaaa     6420

tgagaggaca tggtacagtg tgggagacag cactaacacg tgctgaataa ctactgtgta     6480

ccaggcactg tgctcggtgc ttgttactgt taactcattt aacccccaca actcatctac     6540

aaagttggca ttaaaatccc caagtcactc agtgagccat gggacctgaa tccgaaccta     6600

gtttatctgg agccataatc tgggctcctc ccatttttcc atactgcttt ccaaaagcat     6660

tgtggttcac tctttggatg gaaccagtcc cgttccgtat gctgtgatct atccctgccg     6720

tggaattcct ccgaggctcc aactccgcag ccagagaagc tgctctctgg cctccgcggg     6780

cagagctctg cttatgactt cgtcttccag aggtccacat ttctcccctt gacgccccct     6840

gtctaccacc tccacctgga aatttgatct ttactgtgct cagtgatcac gaaattggtc     6900

aagcctattc atgttccttc tcatctagaa ttctgtgtga ttgttttagc ataaactgcc     6960

ccgctcccac tgtatcattt cacgatctcc ttttaatgtt tttctttcag ttttgcactg     7020

acagtctggt gacaggtgct gccagggtgc aagttacatt gcaatgttct aaaccttttg     7080

aagtgttctt agcaaaagcc tttctttctg ggtgtttttg tcgaatgagt ctatgaagac     7140

tcaatgcatc catcttgggc tgatcatgcc acagatctca ttccagctat agtactgcca     7200

agaagtgaag tttatcattg aattttacct gtgttgctct cttttaaagt aatgactttg     7260

agatgcatgc tttgtatcat attgaaaagt atgttttatt ttccttaaag ttgtaatatt     7320

gtgtgtgaaa ctgtacatat tttaaatgat gtagctttgg caggttttat ttggttgata     7380

tgattttata ttaaaagaga aggctgcttt catatagcat agcccctgaa ggtgggaata     7440

ctccctgttt gtacaacgct gcttatagtt tgtgattggg gtgggcgaat gtcttcctct     7500

gaaattcttt ggaacccccc acccctgtcc tcccctgaaa ctcccctgtg cacacccctc     7560

tgttctgact gcagagatca aggccctgaa ggagcaggat cttgggcaag tgttttaggg     7620

gacgctgaga acatacctga ccctgggggc gatgtggagg caggcccacc tcctcggggc     7680

aactttgcgt ttccttggag ggaagggagg tgggtaggag aggagcttgg gaggatgagg     7740

aggagcggtc ccgcctcaca cattgtctat ttttaccatt aaccgagcgc cacatgttta     7800

tgaacttcag gatagaaatt tagcctcctt gtgaaaacgt tttgttttac tgccctaaga     7860

aaatacacat ctctaggctt gtctgaccag aaagccagca aagtcttttg catcgggtgt     7920

ggcccttttg tattttattt cccatattta aataagcctt ccttaaaccc tagccccagt     7980

cctgagagct ttgagggtag ccgaaacccc ttatctaata aagtctaact ctgtgagaac     8040

cacagaaaaa a                                                          8051


<210>  2236
<211>  17035
<212>  DNA
<213>  homo sapiens

<400>  2236
acttagacac ttccagctgg tggcagggga tacagccata atacagcttc ctctgtccca       60

gctgtcttct tcactacggt aaatgcatta cgatggctgc actctcctgt aaaggttcag      120

gtagaggaag gtgtaggatg aagtccggac accatcattt gggtttttaa aagcttcagc      180

ttctccagca tctttgcatt gtgaatatct tcctgcttct agtcaaagct ttctctctag      240

tgattggaat gctgctgtaa gcctgattag aggtgcctga ggatatcacc ttttacaagg      300

aagccgtgtg tgcttgagag gatcttttta aatgcattat ggctcatgca gcctcacaat      360

taaagaaaaa cagggattta gaaatcaatg ctgaagaaga gcctgagaaa aaaaggaaac      420

accgcaaacg gtcccgggat cggaagaaaa agtctgatgc caatgcaagt tacttaagag      480

cagctcgagc tggacacctt gaaaaggccc tcgactacat aaaaaatgga gttgacatca      540

acatttgcaa tcagaatggg ttgaacgctc tccaccttgc ttccaaagaa ggccatgtag      600

aggttgtttc tgagctgctg cagagagaag ccaatgtgga tgcagctaca aagaaaggaa      660

acacagcatt gcacatcgca tctttggctg ggcaagcaga ggtggtaaaa gtcttggtta      720

caaatggagc caatgtcaat gcacaatctc agaatggttt cacgccattg tatatggcag      780

cccaggaaaa tcacctggaa gttgtcaagt ttcttcttga caatggtgca agccagagcc      840

tagccacaga ggatggcttc acaccattgg cagtggcttt gcaacaaggt cacgaccaag      900

tcgtttcgct cctgctagag aatgacacca aaggaaaagt gcgtctccca gctcttcata      960

tcgcggcccg aaaagacgac acgaaagccg ccgccctgct gctgcagaat gacaacaatg     1020

cagatgtgga atcaaagagt ggcttcactc cgctccacat agctgctcac tatggaaata     1080

tcaatgtagc cacgttgctg ttaaaccgag cggctgctgt ggatttcacc gcaaggaatg     1140

acatcactcc tttacatgtt gcatcaaaaa gaggaaatgc aaatatggta aaactattgc     1200

tcgatcgagg agctaaaatc gatgccaaaa ccagggatgg tctgacacca ctgcactgtg     1260

gagcaaggag tggccacgag caggtggtag aaatgttgct tgatcgagct gcccccattc     1320

tttcaaaaac caagaatgga ttatctccat tgcacatggc cacacaaggg gatcatttaa     1380

actgcgtcca gcttctcctc cagcataatg tacccgtgga tgatgtcacc aatgactacc     1440

tgactgccct acacgtggct gcccactgtg gccattacaa agttgccaag gttctcttgg     1500

ataagaaagc taaccccaat gccaaagccc tgaatggctt tacccctctt catattgcct     1560

gcaagaagaa tcgaattaaa gtaatggaac tccttctgaa acacggtgca tccatccaag     1620

ctgtaaccga gtcgggcctt accccaatcc atgttgctgc cttcatgggg catgtaaata     1680

ttgtatcaca actaatgcat catggagcct caccaaacac caccaatgtg agaggagaaa     1740

cagcactgca catggcagct cgctccggcc aagctgaagt tgtgcggtat ctggtacaag     1800

acggagctca ggtagaagct aaagctaagg atgaccaaac accactccac atttcagccc     1860

gactggggaa agcagacata gtacaacagc tgttgcagca aggggcatct ccaaatgcag     1920

ccacaacttc tgggtacacc ccacttcacc tttccgcccg agaggggcat gaggatgtgg     1980

ccgcgttcct tttggatcat ggagcgtctt tatctataac aacaaagaaa ggatttactc     2040

ctcttcatgt ggcagcaaaa tatggaaagc ttgaagtcgc caatctcctg ctacagaaaa     2100

gtgcatctcc agatgctgct gggaagagcg ggctaacacc actgcatgta gctgcacatt     2160

acgataatca gaaagtggcc cttctgcttt tggaccaagg agcctcacct cacgcagccg     2220

caaagaatgg ttatacgcca ctgcacatcg ctgccaaaaa gaaccagatg gacatagcga     2280

caactctgct ggaatatggt gctgatgcca acgcagttac ccggcaagga attgcttccg     2340

tccatctcgc agctcaggaa gggcacgtgg acatggtgtc gctgctcctc ggtagaaatg     2400

cgaatgtgaa cctgagcaat aagagcggcc tgaccccact ccatttggct gctcaagaag     2460

atcgagtgaa tgtggcagaa gtcctcgtaa accaaggggc tcatgtggac gcccagacaa     2520

agatgggata cacaccactg catgtgggct gccactatgg aaatatcaag attgttaatt     2580

tcctgctcca gcattctgca aaagttaatg ccaaaacaaa gaatgggtat acgccattac     2640

atcaagcagc acagcagggg catacgcata taataaatgt cttacttcag aacaacgcct     2700

cccccaatga actcactgtg aatgggaata ctgcccttgg cattgcccgg cgcctcggct     2760

acatctcagt agtggacacc ctgaagatag tgaccgaaga gaccatgacc acaactactg     2820

tcacagagaa gcacaaaatg aatgttccag aaacgatgaa tgaagttctt gatatgtctg     2880

atgatgaagt tcgtaaagcc aatgcccctg aaatgctcag tgatggcgaa tatatctcag     2940

atgttgaaga aggtgaagat gcaatgaccg gggacacaga caaatatctt gggccacagg     3000

accttaagga attgggtgat gattccctgc ctgcagaggg ttacatgggc tttagtctcg     3060

gagcgcgttc tgccagcctc cgctccttca gttcggatag gtcttacacc ttgaacagaa     3120

gctcctatgc acgggacagc atgatgattg aagaactcct tgtgccatcc aaagagcagc     3180

atctaacatt cacaagggaa tttgattcag attctcttag acattacagc tgggctgcag     3240

acaccttaga caatgtcaat cttgtttcaa gccccattca ttctgggttt ctggttagct     3300

ttatggtgga cgcgagaggg ggctccatga gaggaagccg tcatcacggg atgagaatca     3360

tcattcctcc acgcaagtgt acggccccca ctcgaatcac ctgccgtttg gtaaagagac     3420

ataaactggc caacccaccc cccatggtgg aaggagaggg attagccagt aggctggtag     3480

aaatgggtcc tgcaggggca caatttttag gccctgtcat agtggaaatc cctcactttg     3540

ggtccatgag aggaaaagag agagaactca ttgttcttcg aagtgaaaat ggtgaaactt     3600

ggaaggagca tcagtttgac agcaaaaatg aagatttaac cgagttactt aatggcatgg     3660

atgaagaact tgatagccca gaagagttag ggaaaaagcg tatctgcagg attatcacga     3720

aagatttccc ccagtatttt gcagtggttt cccggattaa gcaggaaagc aaccagattg     3780

gtcctgaagg tggaattctg agcagcacca cagtgcccct tgttcaagca tctttcccag     3840

agggtgccct aactaaaaga attcgagtgg gcctccaggc ccagcctgtt ccagatgaaa     3900

ttgtgaaaaa gatccttgga aacaaagcaa cttttagccc aattgtcact gtggaaccaa     3960

gaagacggaa attccataaa ccaatcacaa tgaccattcc ggtgcccccg ccctcaggag     4020

aaggtgtatc caatggatac aaaggggaca ctacacccaa tctgcgtctt ctctgtagca     4080

ttacaggggg cacttcgcct gctcagtggg aagacatcac aggaacaact cctttgacgt     4140

ttataaaaga ttgtgtctcc tttacaacca atgtttcagc cagattttgg cttgcagact     4200

gccatcaagt tttagaaact gtggggttag ccacgcaact gtacagagaa ttgatatgtg     4260

ttccatatat ggccaagttt gttgtttttg ccaaaatgaa tgatcccgta gaatcttcct     4320

tgcgatgttt ctgcatgaca gatgacaaag tggacaaaac tttagagcaa caagagaatt     4380

ttgaggaagt cgcaagaagc aaagatattg aggttctgga aggaaaacct atttatgttg     4440

attgttatgg aaatttggcc ccacttacca aaggaggaca gcaacttgtt tttaactttt     4500

attctttcaa agaaaataga ctgccatttt ccatcaagat tagagacacc agccaagagc     4560

cctgtggtcg tctgtctttt ctgaaagaac caaagacaac aaaaggactg cctcaaacag     4620

cggtttgcaa cttaaatatc actctgccag cacataaaaa ggagacagag tcagatcaag     4680

atgatgagat tgagaaaaca gatagacgac agagcttcgc atccttagct ttacgtaagc     4740

gctacagcta cttgactgag cctggaatga ttgaacggag tacaggagca acaagatccc     4800

tccccaccac ttactcatac aagccattct tttctacaag accataccag tcctggacaa     4860

cagctccgat tacagtgcct gggccagcca agtcaggctt cacttcctta tcaagttctt     4920

cctctaatac gccatcagct tctccgttaa aatcaatatg gtctgtttcg acaccttctc     4980

caatcaaatc cacattaggc gcgtcaacta catcttcagt taaatccatt agtgacgtgg     5040

catctccaat tagatccttt cggacaatgt cttcgccgat aaaaactgtg gtgtcacaat     5100

ctccatacaa tatccaagtt tcctctggta ccctggctag agctccagca gtcacggaag     5160

ctacgccctt aaaagggctg gcatccaatt ctacgttttc ctctcgaacc tctccagtga     5220

ctacagcagg gtctcttttg gagaggtcat caattactat gacaccccct gcctccccca     5280

aatcaaacat taatatgtat tcctcaagtt tgccatttaa gtcaattatt acatcagcag     5340

caccgctaat atcttcacct ttaaagtcag tggtgtctcc agttaaatca gcagttgatg     5400

tcatttcatc agccaaaatt acaatggcat cttctctctc atcacctgtg aagcagatgc     5460

ctggacatgc agaggtagca ttagtcaatg gatctatttc ccctctaaaa tatccatcat     5520

cctcaacttt aattaatgga tgcaaagcca ctgccacgtt acaggaaaaa atttcttctg     5580

ctacaaactc tgtgagctct gtggtcagtg cagccactga cacagttgag aaagtgtttt     5640

ctaccacgac tgcaatgcca ttttccccac tcaggtcata tgtttctgca gcaccatcag     5700

cttttcagtc tctaagaact ccttccgcaa gtgcactcta tacatccctt gggtcgtcaa     5760

tatctgcaac tacctcatct gtaacttcat caattataac agtgccagta tactctgtag     5820

tcaatgtttt gccagaacca gcattaaaga aacttccaga ctctaattca tttacaaaat     5880

cagcagcagc cttgctgtca cccattaaaa cattgactac ggagacacat cctcagcctc     5940

acttcagtcg aacttcatct ccagttaagt catctttgtt ccttgcaccc tctgccctta     6000

agttgtctac accatcttct ttatcttcca gtcaggagat actaaaagat gtagctgaaa     6060

tgaaagagga cctaatgcgg atgaccgcaa tactacagac agatgtgcct gaggagaagc     6120

cattccaacc tgaactccca aaggaaggga gaatagatga tgaagaacct ttcaaaattg     6180

tagagaaagt aaaggaagac ttagtgaaag ttagtgaaat ccttaaaaag gatgtatgtg     6240

tagataataa aggatcaccc aaatcaccaa agagtgacaa aggacactct cctgaagatg     6300

actggataga atttagttcg gaagaaatcc gggaagccag acaacaagct gctgcgagcc     6360

agtctccatc tctgccagag agagtgcaag taaaagcaaa agccgcctcc gaaaaggatt     6420

ataacttgac caaagttatt gattacctaa caaatgatat tgggagtagt tcactgacaa     6480

acttaaaata caagtttgag gatgcaaaga aggatggtga ggagagacag aaaagagttt     6540

taaaaccagc aattgctttg caggaacaca aactcaaaat gcctccagcc tccatgagga     6600

cttccacctc tgagaaagaa ttgtgtaaaa tggctgattc cttttttgga acagatacta     6660

ttttagagtc tcctgatgac ttttctcaac acgaccaaga taaaagtccc ttgtctgaca     6720

gtggctttga aacaagaagt gaaaagacac cttcagcccc acaaagcgct gaaagcactg     6780

gtcctaaacc actttttcat gaagttccca tccctcctgt cattacagaa acaagaactg     6840

aagtggttca tgttatcagg agctatgatc cctcagctgg ggatgttccc cagacccaac     6900

cagaggagcc tgtgtcacct aaaccttcac ctacttttat ggaattggaa ccaaagccca     6960

ccacctctag tattaaagaa aaggttaaag catttcaaat gaaagccagt agtgaagaag     7020

atgaccacaa tcgggtttta agcaaaggca tgcgtgttaa agaagagact cacataacca     7080

caaccaccag aatggtttat cattctccac caggcggtga aggtgcatct gaaagaattg     7140

aagaaaccat gtcagtccat gacatcatga aggcctttca gtccgggcgg gatccttcca     7200

aagaactggc aggtctgttt gaacataagt cggcagtgtc tccagatgtt cacaagtctg     7260

ctgctgaaac ctcagcccag catgcagaga aggacaacca aatgaaaccc aaactggagc     7320

gtataataga agtccacatc gaaaaaggta accaagctga gcccactgaa gtcattatta     7380

gagaaaccaa aaagcatcca gaaaaagaaa tgtatgtata tcagaaagac ttatcccggg     7440

gagatattaa cctaaaagat tttctgccag aaaaacacga tgcttttcct tgttcagagg     7500

aacagggtca gcaagaagaa gaagaactta ctgctgaaga gtcattgcct tcttatctgg     7560

agtcttccag agtaaacact cctgtgtccc aagaagaaga tagccgccct agttctgctc     7620

aactcatatc tgatgactct tataaaacat tgaagctttt gagtcaacac tcaatagaat     7680

accatgacga tgagttgtca gaactaagag gggagtctta caggtttgct gagaaaatgc     7740

ttctgtcaga aaagctagat gtgtctcatt ctgatactga ggaatcggtt acagaccatg     7800

caggaccccc tagctcagag ttacaggggt ctgataagcg gtccagagaa aaaatagcca     7860

ctgcccccaa aaaagaaatt ctctccaaaa tctataaaga tgtttctgaa aatggtgtag     7920

gtaaagtgtc taaagatgag cattttgata aagtgacagt gttgcactat tctggcaatg     7980

ttagtagtcc aaaacatgcc atgtggatgc gctttactga ggacagatta gacagaggta     8040

gagagaagtt gatatatgaa gatagggtgg acaggactgt gaaggaggct gaagaaaaac     8100

tgactgaagt gtcacagttt tttcgtgaca aaactgaaaa gctaaatgat gaactgcagt     8160

ccccagagaa aaaggcacgc cctaaaaatg gcaaagaata ttcttctcaa agccctacca     8220

gtagcagccc tgagaaagtg ctactgacag aactgctggc atccaatgat gagtgggtta     8280

aggcaagaca gcatggccct gatggacaag gcttccccaa ggccgaggag aaggcaccca     8340

gtctgcccag cagcccagag aagatggttc tctcccaaca gactgaggac agcaagtcca     8400

cagtggaagc caaaggaagt atttcacaga gcaaagcacc agatgggccc cagtctggat     8460

tccagctcaa acaatctaaa ctcagttcca ttagattaaa atttgaacaa ggcacacacg     8520

caaaaagtaa ggacatgtct caagaagaca gaaagtcaga tggccagtcc agaatcccag     8580

ttaaaaaaat acaggagagc aagctacccg tctaccaagt ttttgctaga gaaaaacagc     8640

agaaggccat agacctccca gatgaaagtg tatctgtgca aaaagatttt atggtattaa     8700

aaaccaaaga tgagcatgcc caaagcaacg aaattgttgt aaatgattct ggctctgata     8760

atgtgaaaaa acagagaact gaaatgtcaa gtaaagcaat gcctgactct ttttctgagc     8820

agcaggctaa agacttggca tgtcatataa cctcagattt agcaactagg ggaccatggg     8880

acaaaaaggt ctttagaaca tgggagagtt cgggagccac taacaataag tctcagaaag     8940

aaaaactttc gcatgtactt gttcatgatg taagagagaa tcacattggt caccctgaga     9000

gtaaaagtgt tgatcaaaag aatgaattta tgtctgtgac tgagagagaa cgcaaattgt     9060

taacaaacgg ctctctctca gaaattaaag aaatgactgt aaaatctccc tccaaaaaag     9120

tcttatatag ggaatatgtt gtgaaagaag gggaccatcc aggcggattg cttgatcagc     9180

cttccaggag gagcgagagc tcagcagtgt cacacattcc cgtcagagtt gctgatgaga     9240

ggagaatgct gtcttctaat attcccgatg gtttttgtga acagtcggca tttccaaaac     9300

atgaactatc acaaaaattg tcccagtcaa gcatgagtaa agagacagtt gagacacagc     9360

actttaattc tatagaagat gaaaaagtta cctattcaga aatcagcaaa gtttccaaac     9420

accagagtta tgtaggttta tgcccacctc tcgaggaaac cgaaacctcc cccaccaaat     9480

ctcctgattc tttagagttt agcccaggaa aggaatctcc ctctagtgat gtattcgacc     9540

acagtcccat tgatggattg gaaaaactcg caccactagc ccagacagag ggagggaaag     9600

agataaaaac tttacccgtt tatgtcagtt ttgtacaagt ggggaagcaa tatgaaaagg     9660

agatacaaca aggaggtgta aaaaaaatca taagtcagga atgtaagaca gtacaagaaa     9720

ccagggggac cttttataca actagacagc aaaagcaacc tccttctccc caaggtagtc     9780

cagaagatga tactctagag caagtatcct ttctagacag ctctgggaaa agccctttaa     9840

ccccagaaac acccagttca gaggaagtga gttatgaatt tacatctaag acacctgact     9900

cgctcatagc ttatatacca ggcaaaccca gcccaattcc cgaggtttct gaggagtcag     9960

aggaggagga acaggccaag tcaacctccc ttaagcagac tacagtggag gaaacagcag    10020

ttgagcgtga aatgcctaat gacgtgagca aagactctaa ccaaagaccc aaaaataaca    10080

gagttgccta tattgaattt ccccctcctc caccactgga tgcggaccag attgagtcag    10140

ataagaagca tcattatctc ccagaaaaag aggttgacat gattgaagtc aatctgcaag    10200

atgagcatga caagtaccag ctggctgaac ctgtcattag agtgcagcca ccttcaccag    10260

ttcctcccgg ggcagacgtc agtgattcaa gcgatgacga atctatttat cagccagtcc    10320

cagttaaaaa atataccttc aaattaaagg aagtggacga tgaacaaaaa gaaaaaccca    10380

aagcttctgc tgaaaaggct tccaaccaga aagaactgga aagtaatgga tctggaaaag    10440

ataatgaatt tggccttggc cttgattcac ctcagaatga aattgcccag aatgggaaca    10500

acgaccagtc catcacagag tgttccattg ccaccacagc agagttttct catgacacgg    10560

atgccacaga gatcgactct ctggatggct atgacctgca agatgaagat gatggcttga    10620

cagagagtga ttctaaactc ccaattcaag ccatggaaat taagaaagat atctggaaca    10680

cagagggcat tctgaagcca gctgaccgct cttttagcca aagtaaactt gaagttatcg    10740

aggaggaggg aaaggtggga ccagatgagg acaagccacc ttctaaaagt tcttcatctg    10800

aaaagactcc tgataagact gatcagaagt caggggccca gttcttcaca ctggaaggca    10860

gacatcctga cagatcagtg tttcctgata cttacttcag ttacaaagta gatgaagaat    10920

ttgccactcc ttttaaaaca gtagctacca aaggtctaga ttttgaccct tggtctaata    10980

accgagggga tgatgaagtt tttgacagta aatcacggga agatgaaact aagccatttg    11040

ggctggcggt agaagaccgc tctccagcaa caacccctga tacaacgcca gccagaacgc    11100

caactgatga aagtacccca actagtgagc ctaacccctt cccatttcat gaaggaaaaa    11160

tgtttgagat gactcgcagt ggtgcaattg acatgagcaa gagggatttt gttgaagaga    11220

ggctccaatt tttccagatt ggtgagcata cttctgaagg gaagtcaggg gaccaggggg    11280

aaggggataa aagtatggtc actgccacac cacagccaca gtcaggggac accactgtag    11340

aaaccaatct agagagaaat gtagagacac ctacagtgga acctaacccc agcatcccga    11400

ccagcggaga gtgtcaggaa ggcacatcca gtagtggctc cctggagaaa tcagcagcag    11460

ccactaacac ctctaaagtt gaccccaagt tgcgcacgcc tataaaaatg ggaatttctg    11520

catccaccat gaccatgaag aaagaaggcc ctggagaaat aacagataag atagaagcgg    11580

tgatgaccag ttgtcaggga ttagaaaatg aaactataac aatgatttca aatacagcca    11640

atagccagat gggcgttagg ccccatgaaa aacatgattt tcaaaaagat aactttaata    11700

acaacaacaa tttggattct tccactatac agacagataa cattatgagt aatatagttc    11760

tgacagaaca ttctgcaccc acttgtacca cagagaaaga taacccagtg aaagtctcat    11820

caggaaaaaa gacaggggta ctacaaggac actgtgtaag agataagcag aaagttcttg    11880

gagaacagca aaaaacaaag gaattgatag ggattaggca aaaatccaaa cttcccataa    11940

aggccacttc accaaaagat accttcccac cgaaccatat gtcaaacact aaagcaagta    12000

aaatgaagca ggttagtcaa tccgagaaaa ccaaagccct tactacttct tcatgtgtag    12060

atgtaaagtc cagaattcca gtgaaaaaca cacacaggga taacataatt gcagttagaa    12120

aagcatgtgc cacacaaaag caagggcagc cagagaaagg caaggccaaa cagcttccat    12180

ccaagttgcc agtaaaggta agatccacct gtgtcactac caccaccacc actgccacca    12240

ccaccaccac taccaccact accaccacca ccagctgcac agttaaagtt aggaaaagtc    12300

agctcaagga agtatgtaaa cattccattg aatattttaa gggaattagt ggtgagacct    12360

taaagcttgt ggaccgcctc tctgaagaag aaaaaaagat gcagtccgag ttgtccgatg    12420

aggaagaaag tacctcaaga aacacgtcgt tgtccgagac ttcccggggt ggccagcctt    12480

cggttacaac gaagtctgct agagataaga aaacagaggc agcaccttta aaatcaaaga    12540

gtgaaaaggc cggcagtgag aaaaggagca gtagaaggac tggtccacag agtccatgtg    12600

aacggacaga tatcaggatg gcaatagtag ccgatcacct gggacttagt tggacagaac    12660

tggcaaggga actgaatttt tcagtggatg aaatcaatca aatacgtgtg gaaaatccaa    12720

attctttaat ttctcagagc ttcatgttat taaaaaaatg ggttaccaga gacggaaaaa    12780

atgccacaac tgatgcctta acttcggtct tgacaaaaat taatcgaata gatatagtga    12840

cactgctaga aggaccaata tttgattatg gaaatatttc aggcaccaga agttttgcag    12900

atgagaacaa tgttttccat gaccctgttg atggttggca gaatgagaca tcaagtggaa    12960

acctagagtc ctgcgctcaa gctcgaagag taactggtgg gttactagat cgactggatg    13020

acagccctga ccagtgtaga gattccatta cctcatatct caaaggagaa gctggcaaat    13080

ttgaagcaaa tggaagccat acagaaatca ctccagaagc aaagacaaaa tcttactttc    13140

cagaatccca aaatgatgta ggaaaacaga gtaccaagga aactctgaaa ccaaaaatac    13200

atggatctgg tcatgttgaa gaaccagcat caccactagc agcatatcag aaatctctag    13260

aagaaaccag caagcttata atagaagaga ctaaaccctg tgtgcctgtc agtatgaaaa    13320

agatgagtag gacttctcca gcagatggca agccaaggct tagcctccat gaagaagagg    13380

ggtccagtgg gtctgagcaa aagcagggag aaggttttaa ggtgaaaacg aagaaagaaa    13440

tccggcatgt ggaaaagaag agccactcgt aacagcgaac ggtcagtcaa ggatcataag    13500

tttttactgc cagtattgag aaattcgtgg aagaaatgtc agcaggaagt aaaaattcac    13560

cgagaagtgt gtgtgtgttc gctgcttcca cacattaatg gcatgatttt ttttatgcaa    13620

aaagaaaaga aaagaaaacc acccacattt taatttagca tgagccaatt tacagagcat    13680

ggaaatcact ttcatttccg gattggcgcg tgtgcaatta gcaatgcagt gtatatacaa    13740

gaagccatgc tgttaacagt ttatctcaag taatttggtg tcatttacaa aaggaagaaa    13800

ttcctgccat cagaagggac agaaggagat ggaatgatca aatcacagag aaacactaaa    13860

attactaaat ctacaacagc tcgccttatt tttcttggac ccaaactgtc agggtataaa    13920

cactatttgt ttctttttta aaacatcgat agttttgctg taaataataa cactgtataa    13980

attctaacag aaaaatagaa taaaatgttg ataaggcact gcctcttaga acacaaacag    14040

aatattgcaa atgcatttaa caaatagggg tctcaagtga cttcacccta gaagaggagg    14100

gagggattct gggtgggggt gactcttcac tgattcttgt atattagcaa ttataatgtt    14160

tgtatatgca aaactgctag cttgatttta aaaaaaaaca aatctttaaa atctgctgca    14220

aatttaaata attcccaaaa tgaggaattc tgtagttctg tgaaaaattt ttttcttcag    14280

aatactaata ttttgatgca tgtgtatcac cttattttga ttaaatcttt tccaattttg    14340

caaacactac agtatactgc aacacaaaag attttatctg taaacacaaa gcccttcatc    14400

taatatttgt tgctattgcc aatttttcaa tgaaatgacc taaaaacaac aaaaaaaaat    14460

aacctatacg gtagttgctt tagggggtgg ggggatgcta tctgttagtg cttaaaaggg    14520

ggtaaatgct tgccgcttta gaggtggatg gtgctcataa aaggccccag tcgggggtat    14580

ttaaaaagga ctgaacagaa atccttagct agtagaatgg cagcacgctg taaaattatt    14640

actgtattgt gtactggcta taagatgtag acacctttca gtaagccaat catttgtaac    14700

cattctagca gtgtcatatt aggttaataa ggctgctgtg ttttaaaggg catttttatt    14760

tgggttttgg tgaaattctt taatttgttg attatattca cataaaatca gcattcattg    14820

acacatagct ctaatgacat atgtatgaaa aaccatacac tggatgacct agtcgattat    14880

ttaagcataa aataaattgt gttaaactct tcacctatct gtgctctaca gtctccttgt    14940

gttttctggc aaaaggtagt tgtctaatcc cttgtcatat gagtcctggc caatccaccc    15000

cattggtcct ctttgtgcct ctgtggtcac tgaagagata atctctaaca ttcatatgtg    15060

ccctgcaagc tcccagctta taaattctgt gcatttcatg ggggagccaa gaattaaaga    15120

ttaattgaca agtaagcttt gcccacatct gttcaggcct tcttgaaaag tgaagaattg    15180

gagatactat agccagcatg tcaaaaagtt gactggcact tctaggaacc atcaacatgc    15240

agttgctttt agcccacaga gcttgttttt gttttgtttt attaatttac atttattgtc    15300

cattcttaca agttgggaca tttcacataa ttaagttgct aacatctctt aaaaagcaag    15360

atttggcaac aatggacctc attcccagaa ggtaacaacc tgctagagcc aagttgtccc    15420

tgccctctcc agccaggtgt ggggtctaca ggtatcactg ccacagcctc atttcttata    15480

tttgtacaac ctgactgtga atttgcaacc catacactgc gtgaatctaa attctactga    15540

ggcagagacc atggctgttt taacttttat tctagttacc agcttagcat atggtagtag    15600

tgatagtagt aactgtgatc atcatcacta aaactggagt gctcactaca tgctattctc    15660

tgttctaagc acattccatt tacttactta gtcctcatat ctactttatg aattaggtac    15720

tgtctttctt tgatggtaat gatcctttta taaaattaaa ttagtgctaa gagactttca    15780

gcaatgttat atattgcctg tccattaaag attgttgcca aatggagtga gttgtcccca    15840

gtaaggattc actatcaatg cagaagaaat gcacggataa tctactttgc ataaagaatg    15900

gggctaggtt gcatctgcat ggtatcccaa ataaataaaa tgtgccacta cccttgcacc    15960

aaaattattt tatgatgggt aaagttagac ccttgagagg tttttttttt aaaaaaaaaa    16020

aaaaaaaaaa actttcccaa aatgcctctc tgtaaagcca ggatcagaat ataggtgtcc    16080

taacttccta tctaagagtt acgaatttct gactcagtct ttgagagaag gtgtttatcc    16140

tgaaccagaa actcaatgat gtatacctgt ttaggtatta aatagttgtg tttatatgcc    16200

caaaaatttg actttaggta tatgtgatat gctttggttc cgatcaagca ggaggtcata    16260

agtttactca gaagtatcca aaatatgaca ttcaagattt aacttgcata tgtgtgtata    16320

tgcatatatt tatacatgta tatgtagatt gaatgtgaca ttatgtattt ctaacataat    16380

atttggcctg ccagcttata aatatgtatt taagcttttc attgattgac attactgtaa    16440

aaaatgaatt atgattgaga agttctggat atttgctgtt tttttcattt tatattctta    16500

ctaaattatt gaatttgtta aattaaaatg tgctatcact gtattgccaa attatggcaa    16560

tacactatgc agtattattt caatacttta agaggcatct attacttcat tgaacacata    16620

agcagctagc ctcctttcct ctgtaaataa ggactttttg gcatcctgat gttcctcgct    16680

gttcatttgg tatcatcctg gagttccatc aagactgagg attttctcca tggccaataa    16740

actattgtca gcatcagctc acgtttggct gtatgacagg gatatgtgag aagcccagaa    16800

ataaatcaca aaaataataa ggcatcttct gagtctctct gaagaagcca gtgatccaaa    16860

aactaacttc atatctgagt gagtcttggt attcttgatt tgcttgaaga ggctgtgaca    16920

tattacaagg tgtgtaattt cccaggcata tcacactgct tctgtttcat gaattgatca    16980

aattgtccag aagtaaacat ttacaagatt gagatttgaa aaaaaaaaaa aaaaa         17035


<210>  2237
<211>  3115
<212>  DNA
<213>  homo sapiens

<400>  2237
acacgctcca ctgacaccag cttcacgctg ccgggcagtc gccgatcacg cgtggccccg       60

cgagcccatt ggccggcgcc tcacacacct ttgccgttga ttggccggcc tcaggctccg      120

cccccacccc cgcccgcggc gcggggcagg ctgagcggct acctgaatgg ggagggggca      180

gacggcgctg agcgcggcgg cggcgggagc ggcgtcgagt gtctccgtgc gcccgtctgt      240

ggccaagcag ccagcagcct agcagccagt cagcttgccg ccggcggcca agcagccaac      300

catgctcaac ttcggtgcct ctctccagca gactgcggag gaaagaatgg aaatgatttc      360

tgaaaggcca aaagagagta tgtattcctg gaacaaaact gcagagaaaa gtgattttga      420

agctgtagaa gcacttatgt caatgagctg cagttggaag tctgatttta agaaatacgt      480

tgaaaacaga cctgttacac cagtatctga tttgtcagag gaagagaatc tgcttccggg      540

aacacctgat tttcatacaa tcccagcatt ttgtttgact ccaccttaca gtccttctga      600

ctttgaaccc tctcaagtgt caaatctgat ggcaccagcg ccatctactg tacacttcaa      660

gtcactctca gatactgcca aacctcacat tgccgcacct ttcaaagagg aagaaaagag      720

cccagtatct gcccccaaac tccccaaagc tcaggcaaca agtgtgattc gtcatacagc      780

tgatgcccag ctatgtaacc accagacctg cccaatgaaa gcagccagca tcctcaacta      840

tcagaacaat tcttttagaa gaagaaccca cctaaatgtt gaggctgcaa gaaagaacat      900

accatgtgcc gctgtgtcac caaacagatc caaatgtgag agaaacacag tggcagatgt      960

tgatgagaaa gcaagtgctg cactttatga cttttctgtg ccttcctcag agacggtcat     1020

ctgcaggtct cagccagccc ctgtgtcccc acaacagaag tcagtgttgg tctctccacc     1080

tgcagtatct gcagggggag tgccacctat gccggtcatc tgccagatgg ttccccttcc     1140

tgccaacaac cctgttgtga caacagtcgt tcccagcact cctcccagcc agccaccagc     1200

cgtttgcccc cctgttgtgt tcatgggcac acaagtcccc aaaggcgctg tcatgtttgt     1260

ggtaccccag cccgttgtgc agagttcaaa gcctccggtg gtgagcccga atggcaccag     1320

actctctccc attgcccctg ctcctgggtt ttccccttca gcagcaaaag tcactcctca     1380

gattgattca tcaaggataa ggagtcacat ctgtagccac ccaggatgtg gcaagacata     1440

ctttaaaagt tcccatctga aggcccacac gaggacgcac acaggagaaa agcctttcag     1500

ctgtagctgg aaaggttgtg aaaggaggtt tgcccgttct gatgaactgt ccagacacag     1560

gcgaacccac acgggtgaga agaaatttgc gtgccccatg tgtgaccggc ggttcatgag     1620

gagtgaccat ttgaccaagc atgcccggcg ccatctatca gccaagaagc taccaaactg     1680

gcagatggaa gtgagcaagc taaatgacat tgctctacct ccaacccctg ctcccacaca     1740

gtgacagacc ggaaagtgaa gagtcagaac taactttggt ctcagcggga gccagtggtg     1800

atgtaaaaat gcttccactg caagtctgtg gccccacaac gtgggcttaa agcagaagcc     1860

ccacagcctg gcacgaaggc cccgcctggg ttaggtgact aaaagggctt cggccacagg     1920

caggtcacag aaaggcaggt ttcatttctt atcacataag agagatgaga aagcttttat     1980

tcctttgaat attttttgaa ggtttcagat gaggtcaaca caggtagcac agattttgaa     2040

tctgtgtgca tatttgttac tttacttttg ctgtttatac ttgagaccaa cttttcaatg     2100

tgattcttct aaagcactgg tttcaagaat atggaggctg gaaggaaata aacattacgg     2160

tacagacatg gagatgtaaa atgagtttgt attattacaa atattgtcat ctttttctag     2220

agttatcttc tttattattc ctagtctttc cagtcaacat cgtggatgta gtgattaaat     2280

atatctagaa ctatcatttt tacactattg tgaatatttg gaattgaacg actgtatatt     2340

gctaagaggg cccaaagaat tggaatcctc cttaatttaa ttgctttgaa gcatagctac     2400

aatttgtttt tgcatttttg ttttgaaagt ttaacaaatg actgtatcta ggcatttcat     2460

tatgctttga actttagttt gcctgcagtt tcttgtgtag atttgaaaat tgtataccaa     2520

tgtgttttct gtagactcta agatacactg cactttgttt agaaaaaaaa ctgaagatga     2580

aatatatatt gtaaagaagg gatattaaga atcttagata acttcttgaa aaagatggct     2640

tatgtcatca gtaaagtacc tttatgttat gaggatataa tgtgtgcttt attgaattag     2700

aaaattagtg accattattc acaggtggac aaatgttgat gttgtcctgt taatttatag     2760

gcgttttttg gggatgtgga ggtagttggg tagaaaaatt attagaacat tcacttttgt     2820

taacagtatt tctcttttat tctgttatat agtggatgat atacacagtg gcaaaacaaa     2880

agtacattgc ttaaaatata tagtgaaaaa tgtcactata tcttcccatt taacattgtt     2940

tttgtatatt gggtgtagat ttctgacatc aaaacttgga cccttggaaa acaaaagttt     3000

taattaaaaa aaatccttgt gacttacaat ttgcacaata tttcttttgt tgtactttat     3060

atcttgttta caataaagaa ttccctttgg tatatggaaa aaaaaaaaaa aaaaa          3115


<210>  2238
<211>  3115
<212>  DNA
<213>  homo sapiens

<400>  2238
acacgctcca ctgacaccag cttcacgctg ccgggcagtc gccgatcacg cgtggccccg       60

cgagcccatt ggccggcgcc tcacacacct ttgccgttga ttggccggcc tcaggctccg      120

cccccacccc cgcccgcggc gcggggcagg ctgagcggct acctgaatgg ggagggggca      180

gacggcgctg agcgcggcgg cggcgggagc ggcgtcgagt gtctccgtgc gcccgtctgt      240

ggccaagcag ccagcagcct agcagccagt cagcttgccg ccggcggcca agcagccaac      300

catgctcaac ttcggtgcct ctctccagca gactgcggag gaaagaatgg aaatgatttc      360

tgaaaggcca aaagagagta tgtattcctg gaacaaaact gcagagaaaa gtgattttga      420

agctgtagaa gcacttatgt caatgagctg cagttggaag tctgatttta agaaatacgt      480

tgaaaacaga cctgttacac cagtatctga tttgtcagag gaagagaatc tgcttccggg      540

aacacctgat tttcatacaa tcccagcatt ttgtttgact ccaccttaca gtccttctga      600

ctttgaaccc tctcaagtgt caaatctgat ggcaccagcg ccatctactg tacacttcaa      660

gtcactctca gatactgcca aacctcacat tgccgcacct ttcaaagagg aagaaaagag      720

cccagtatct gcccccaaac tccccaaagc tcaggcaaca agtgtgattc gtcatacagc      780

tgatgcccag ctatgtaacc accagacctg cccaatgaaa gcagccagca tcctcaacta      840

tcagaacaat tcttttagaa gaagaaccca cctaaatgtt gaggctgcaa gaaagaacat      900

accatgtgcc gctgtgtcac caaacagatc caaatgtgag agaaacacag tggcagatgt      960

tgatgagaaa gcaagtgctg cactttatga cttttctgtg ccttcctcag agacggtcat     1020

ctgcaggtct cagccagccc ctgtgtcccc acaacagaag tcagtgttgg tctctccacc     1080

tgcagtatct gcagggggag tgccacctat gccggtcatc tgccagatgg ttccccttcc     1140

tgccaacaac cctgttgtga caacagtcgt tcccagcact cctcccagcc agccaccagc     1200

cgtttgcccc cctgttgtgt tcatgggcac acaagtcccc aaaggcgctg tcatgtttgt     1260

ggtaccccag cccgttgtgc agagttcaaa gcctccggtg gtgagcccga atggcaccag     1320

actctctccc attgcccctg ctcctgggtt ttccccttca gcagcaaaag tcactcctca     1380

gattgattca tcaaggataa ggagtcacat ctgtagccac ccaggatgtg gcaagacata     1440

ctttaaaagt tcccatctga aggcccacac gaggacgcac acaggagaaa agcctttcag     1500

ctgtagctgg aaaggttgtg aaaggaggtt tgcccgttct gatgaactgt ccagacacag     1560

gcgaacccac acgggtgaga agaaatttgc gtgccccatg tgtgaccggc ggttcatgag     1620

gagtgaccat ttgaccaagc atgcccggcg ccatctatca gccaagaagc taccaaactg     1680

gcagatggaa gtgagcaagc taaatgacat tgctctacct ccaacccctg ctcccacaca     1740

gtgacagacc ggaaagtgaa gagtcagaac taactttggt ctcagcggga gccagtggtg     1800

atgtaaaaat gcttccactg caagtctgtg gccccacaac gtgggcttaa agcagaagcc     1860

ccacagcctg gcacgaaggc cccgcctggg ttaggtgact aaaagggctt cggccacagg     1920

caggtcacag aaaggcaggt ttcatttctt atcacataag agagatgaga aagcttttat     1980

tcctttgaat attttttgaa ggtttcagat gaggtcaaca caggtagcac agattttgaa     2040

tctgtgtgca tatttgttac tttacttttg ctgtttatac ttgagaccaa cttttcaatg     2100

tgattcttct aaagcactgg tttcaagaat atggaggctg gaaggaaata aacattacgg     2160

tacagacatg gagatgtaaa atgagtttgt attattacaa atattgtcat ctttttctag     2220

agttatcttc tttattattc ctagtctttc cagtcaacat cgtggatgta gtgattaaat     2280

atatctagaa ctatcatttt tacactattg tgaatatttg gaattgaacg actgtatatt     2340

gctaagaggg cccaaagaat tggaatcctc cttaatttaa ttgctttgaa gcatagctac     2400

aatttgtttt tgcatttttg ttttgaaagt ttaacaaatg actgtatcta ggcatttcat     2460

tatgctttga actttagttt gcctgcagtt tcttgtgtag atttgaaaat tgtataccaa     2520

tgtgttttct gtagactcta agatacactg cactttgttt agaaaaaaaa ctgaagatga     2580

aatatatatt gtaaagaagg gatattaaga atcttagata acttcttgaa aaagatggct     2640

tatgtcatca gtaaagtacc tttatgttat gaggatataa tgtgtgcttt attgaattag     2700

aaaattagtg accattattc acaggtggac aaatgttgat gttgtcctgt taatttatag     2760

gcgttttttg gggatgtgga ggtagttggg tagaaaaatt attagaacat tcacttttgt     2820

taacagtatt tctcttttat tctgttatat agtggatgat atacacagtg gcaaaacaaa     2880

agtacattgc ttaaaatata tagtgaaaaa tgtcactata tcttcccatt taacattgtt     2940

tttgtatatt gggtgtagat ttctgacatc aaaacttgga cccttggaaa acaaaagttt     3000

taattaaaaa aaatccttgt gacttacaat ttgcacaata tttcttttgt tgtactttat     3060

atcttgttta caataaagaa ttccctttgg tatatggaaa aaaaaaaaaa aaaaa          3115


<210>  2239
<211>  1329
<212>  DNA
<213>  homo sapiens

<400>  2239
gtgcagctgc tggcctcgta gacaatcggc tgtctcccca gaagagggaa agaattgtgc       60

agatgagaaa gaggctctca gcgggaggga ggcaggcggg cttgattgac acaggagagg      120

gctggctttt tggagggctc ttagcaacgg ccctggttga gccccctcag ccatgagaaa      180

atcaaatcaa tgtgccattc ttccaggcgc gaggcagcag cggctgcagt tcaacatgaa      240

aggaggcttc ctccctgcct gctaattacc tgctcttccc gatctcatcg tttctgcctt      300

tgcaaagtgc tactgagaag ggggaagaaa cgtccgccac ccatccccct tgctgcctgg      360

gggttcagac ttgattagat ggctaacagg ggcccgagct atggcttaag ccgagaggtg      420

caggagaaga tcgagcagaa gtatgatgcg gacctggaga acaagctggt ggactggatc      480

atcctgcagt gcgccgagga catagagcac ccgccccccg gcagggccca ttttcagaaa      540

tggttaatgg acgggacggt cctgtgcaag ctgataaata gtttataccc accaggacaa      600

gagcccatac ccaagatctc agagtcaaag atggctttta agcagatgga gcaaatctcc      660

cagttcctaa aagctgcgga gacctatggt gtcagaacca ccgacatctt tcagacggtg      720

gatctatggg aagggaagga catggcagct gtgcagagga ccctgatggc tttaggcagc      780

gttgcagtca ccaaggatga tggctgctat cggggagagc catcctggtt tcacaggaaa      840

gcccagcaga atcggagagg cttttccgag gagcagcttc gccagggaca gaacgtaata      900

ggcctgcaga tgggcagcaa caagggagcc tcccaggcgg gcatgacagg gtacgggatg      960

cccaggcaga tcatgtagga cgcggcatcc tgcccctggt agagaggacg aatgttccac     1020

accatggtct ctacgaaaaa gaaatagtta gtcaccttct gaccttctcc tctttctcaa     1080

agccttctgt ccctggtttt tgcaagtgct gcatttccgc cgagaatccg cgttgcctac     1140

tgctgccacc tcctgttcat ttagaactat gcaaagactc cgcttccgtt ttcctgagct     1200

cctcgggccc cagagtctct gtttgattat ttatttattt atttatttat ttgccaaaaa     1260

ttctcctctt caacttatag aatgcaccta ataaagtaat tagtcttgtg tcttaaaaaa     1320

aaaaaaaaa                                                             1329


<210>  2240
<211>  1214
<212>  DNA
<213>  homo sapiens

<400>  2240
ggagggggat tccagccccc ctggaccggc cggaggttta ttctagagtt actggcgggt       60

agctgtgctt ttctttcccg tttgtaggtg aaaccccatt ggcttcattg gctccttgat      120

ttaaaccacg cccggctttc tgccctcttt gctgctgctg ggccaggttg cccagccata      180

tcccagcccc gtctgcaggg agccggaggc tgctgctgct gctattgtgt ggatgccgcg      240

cgtgtcttct cttctttcca gagatggcta acaggggccc gagctatggc ttaagccgag      300

aggtgcagga gaagatcgag cagaagtatg atgcggacct ggagaacaag ctggtggact      360

ggatcatcct gcagtgcgcc gaggacatag agcacccgcc ccccggcagg gcccattttc      420

agaaatggtt aatggacggg acggtcctgt gcaagctgat aaatagttta tacccaccag      480

gacaagagcc catacccaag atctcagagt caaagatggc ttttaagcag atggagcaaa      540

tctcccagtt cctaaaagct gcggagacct atggtgtcag aaccaccgac atctttcaga      600

cggtggatct atgggaaggg aaggacatgg cagctgtgca gaggaccctg atggctttag      660

gcagcgttgc agtcaccaag gatgatggct gctatcgggg agagccatcc tggtttcaca      720

ggaaagccca gcagaatcgg agaggctttt ccgaggagca gcttcgccag ggacagaacg      780

taataggcct gcagatgggc agcaacaagg gagcctccca ggcgggcatg acagggtacg      840

ggatgcccag gcagatcatg taggacgcgg catcctgccc ctggtagaga ggacgaatgt      900

tccacaccat ggtctctacg aaaaagaaat agttagtcac cttctgacct tctcctcttt      960

ctcaaagcct tctgtccctg gtttttgcaa gtgctgcatt tccgccgaga atccgcgttg     1020

cctactgctg ccacctcctg ttcatttaga actatgcaaa gactccgctt ccgttttcct     1080

gagctcctcg ggccccagag tctctgtttg attatttatt tatttattta tttatttgcc     1140

aaaaattctc ctcttcaact tatagaatgc acctaataaa gtaattagtc ttgtgtctta     1200

aaaaaaaaaa aaaa                                                       1214


<210>  2241
<211>  4724
<212>  DNA
<213>  homo sapiens

<400>  2241
ggcgggcgct cggcgactcg tccccggggc cccgcgcggg cccgggcagc aggggcgtga       60

tgtcacggca gggagggggc gcgggagccg ccgggccggc ggggaggcgg gggaggtgtt      120

ttccagcttt aaaaaggcag gaggcagagc gcggccctgc gtcagagcga gactcagagg      180

ctccgaactc gccggcggag tcgccgcgcc agatcccagc agcagggcgc gggcaccggg      240

gcgcgggcag ggctcggagc caccgcgcag gtcctagggc cgcggccggg ccccgccacg      300

cgcgcacacg cccctcgatg actttcctcc ggggcgcgcg gcgctgagcc cggggcgagg      360

gctgtcttcc cggagacccg accccggcag cgcggggcgg ccgcttctcc tgtgcctccg      420

cccgccgctc cactccccgc cgccgccgcg cggatgccaa gcaccagctt tccagtccct      480

tccaagtttc cacttggccc tgcggctgcg gtcttcggga gaggagaaac tttggggccc      540

gcgccgcgcg ccggcggcac catgaagtca gcggaggaag aacactatgg ctatgcatcc      600

tccaacgtca gccccgccct gccgctcccc acggcgcact ccaccctgcc ggccccgtgc      660

cacaaccttc agacctccac accgggcatc atcccgccgg cggatcaccc ctcggggtac      720

ggagcagctt tggacggtgg gcccgcgggc tacttcctct cctccggcca caccaggcct      780

gatggggccc ctgccctgga gagtcctcgc atcgagataa cctcgtgctt gggcctgtac      840

cacaacaata accagttttt ccacgatgtg gaggtggaag acgtcctccc tagctccaaa      900

cggtccccct ccacggccac gctgagtctg cccagcctgg aggcctacag agacccctcg      960

tgcctgagcc cggccagcag cctgtcctcc cggagctgca actcagaggc ctcctcctac     1020

gagtccaact actcgtaccc gtacgcgtcc ccccagacgt cgccatggca gtctccctgc     1080

gtgtctccca agaccacgga ccccgaggag ggctttcccc gcgggctggg ggcctgcaca     1140

ctgctgggtt ccccgcggca ctccccctcc acctcgcccc gcgccagcgt cactgaggag     1200

agctggctgg gtgcccgctc ctccagaccc gcgtcccctt gcaacaagag gaagtacagc     1260

ctcaacggcc ggcagccgcc ctactcaccc caccactcgc ccacgccgtc cccgcacggc     1320

tccccgcggg tcagcgtgac cgacgactcg tggttgggca acaccaccca gtacaccagc     1380

tcggccatcg tggccgccat caacgcgctg accaccgaca gcagcctgga cctgggagat     1440

ggcgtccctg tcaagtcccg caagaccacc ctggagcagc cgccctcagt ggcgctcaag     1500

gtggagcccg tcggggagga cctgggcagc cccccgcccc cggccgactt cgcgcccgaa     1560

gactactcct ctttccagca catcaggaag ggcggcttct gcgaccagta cctggcggtg     1620

ccgcagcacc cctaccagtg ggcgaagccc aagcccctgt cccctacgtc ctacatgagc     1680

ccgaccctgc ccgccctgga ctggcagctg ccgtcccact caggcccgta tgagcttcgg     1740

attgaggtgc agcccaagtc ccaccaccga gcccactacg agacggaggg cagccggggg     1800

gccgtgaagg cgtcggccgg aggacacccc atcgtgcagc tgcatggcta cttggagaat     1860

gagccgctga tgctgcagct tttcattggg acggcggacg accgcctgct gcgcccgcac     1920

gccttctacc aggtgcaccg catcacaggg aagaccgtgt ccaccaccag ccacgaggcc     1980

atcctctcca acaccaaagt cctggagatc ccactcctgc cggagaacag catgcgagcc     2040

gtcattgact gtgccggaat cctgaaactc agaaactccg acattgaact tcggaaagga     2100

gagacggaca tcgggaggaa gaacacacgg gtacggctgg tgttccgcgt tcacgtcccg     2160

caacccagcg gccgcacgct gtccctgcag gtggcctcca accccatcga atgctcccag     2220

cgctcagctc aggagctgcc tctggtggag aagcagagca cggacagcta tccggtcgtg     2280

ggcgggaaga agatggtcct gtctggccac aacttcctgc aggactccaa ggtcattttc     2340

gtggagaaag ccccagatgg ccaccatgtc tgggagatgg aagcgaaaac tgaccgggac     2400

ctgtgcaagc cgaattctct ggtggttgag atcccgccat ttcggaatca gaggataacc     2460

agccccgttc acgtcagttt ctacgtctgc aacgggaaga gaaagcgaag ccagtaccag     2520

cgtttcacct accttcccgc caacgttcca attataaaaa cagaacccac tgatgattat     2580

gagcctgctc caacctgtgg accggtgagc caggggttaa gtcctctccc aagaccatac     2640

tacagccagc agctcgcgat gccacccgac cccagctcct gcctcgtggc cggcttcccg     2700

ccctgtccgc agagaagcac cctgatgcca gcggcccctg gcgtgagccc caagctccac     2760

gacctttctc ccgctgccta caccaagggc gttgccagcc cgggccactg tcacctcgga     2820

ctcccgcagc cggccggaga ggcccccgcc gtccaggacg tgcccaggcc agtggccacg     2880

caccccggct cgcccgggca gccacccccg gccctgctgc cacagcagta aatgaaataa     2940

tacgaaatga cctctccagc acgagcaccc actcctagtt gccacattgg agcactcagt     3000

tcagcagggg tatgctgact tcagcagaca aagacttttg aataaataaa ctgaactcac     3060

acctggtacc actcagaacc tccaactgac tgaatgccag gagctgaaca ttaatatgtg     3120

caaagattgg ctctccaaca agaaggaaag cagggaggaa gggagaccac tgtgtcacct     3180

ggaggagaag tcatctcatg acaacagaag ggaggtggcc gggctgagca cgggagaccc     3240

accgtgcagg ggcctttcat gggaacggcc cacacgcagt ttgaccccac gcccagccct     3300

tctggcaccc ctggggttca atactggaag tgccttattt aaccagacca tcagggcatc     3360

atagaattga gcattgaatt tgctactgta ggagtatttt taggagcaga aactgcaaac     3420

acatttcatt gtgaggtttt accctctgta tgaatgaaga gaacgctgga aggctgcgag     3480

aggactctag tatgagtctc caacatttgg aacgtttcct gggctgtcac gtacactcct     3540

gctgccttac acagtgcatt ttagaatctt ccagtctgtc atctcagctc ttttgtaaca     3600

tgcttccctt gtctgcgcgg ttgaaaccgt aggcttgttc atagtcgcat gctcgcatct     3660

ttgtttttaa tctggcttcg aacatagcac aagtaacttg aatagcacat caataggtta     3720

ctggacaaaa gcagaaaaac ctgttacagg atagcctgca tttgcatgtg tgtacatatc     3780

taggcatcta tttatgtata aataataaca gagccgacgt gtcctcgccc aggagggctt     3840

ccctgtcagc aataaccggc atccgttttg gaacctgcgt ctggggctcc agtcgctgct     3900

cttgctggcg tccatcgccg cctcggacgg ccgtgcattt tctcgtctca cgcagttcga     3960

ggaggaccct agaaagccag gagctgtgat tgacagtagc tgtaggttac cagacggcaa     4020

cattagaaag tgattgtaaa taacatgcaa cctaagtgta atatatttgt tcagttataa     4080

gatgattgtt tcacagaagc cttaccactc tctgcttcat ctaagaaaac caataccaaa     4140

aacgccactt taatgctcag ccctgcgttg tgtgttttca gatgagttac tgttaacagg     4200

taggtttgtg taggccttgc tgggcactct gtacaattag ttgcttatta cgtatgatta     4260

ctcacagcga tctattgttc catataacca aaaagcatgg tttattcatt gaaacacggt     4320

tgacctgaac tcgtgcctta ggaattaatg cccccttatg gaacctgcct gaattgcacc     4380

tgcgggtgga ggctccggct gtgaagtcac tgaacagaac gtcgctgatg gagaaagggc     4440

tcccgcagaa ggaacggcct gtaccgtgcg ctccggcaca atcgcgtctc ttgtgtctca     4500

ctcacggaaa gaaacaacct gaaggccatc ccgtcggtct gcacgtaacc gtgaagacgt     4560

gtggccgcgt cccacctgcg gctgggtacc ctgcacccgg cactgtagga gtcacgtgca     4620

gcctttctca ggggactgtc attgaaaagg aaacgtttga tgtctgtgtc agctgtcttt     4680

gtagttagga aatagatcca ataaagccgt atttttttgc tgga                      4724


<210>  2242
<211>  4657
<212>  DNA
<213>  homo sapiens

<400>  2242
ggggacgggg ggaggggcgg gggtcacgtt acgcggagga cgcgcgggca gcgccgggag       60

aaccgaaccc ctggcggccg cgaccccggc tcccgccccg gccccggccc gacccgccat      120

gacggggctg gaggaccagg agttcgactt cgagttcctc ttcgagttta accagcgcga      180

cgagggcgcc gccgcggccg ccccagaaca ctatggctat gcatcctcca acgtcagccc      240

cgccctgccg ctccccacgg cgcactccac cctgccggcc ccgtgccaca accttcagac      300

ctccacaccg ggcatcatcc cgccggcgga tcacccctcg gggtacggag cagctttgga      360

cggtgggccc gcgggctact tcctctcctc cggccacacc aggcctgatg gggcccctgc      420

cctggagagt cctcgcatcg agataacctc gtgcttgggc ctgtaccaca acaataacca      480

gtttttccac gatgtggagg tggaagacgt cctccctagc tccaaacggt ccccctccac      540

ggccacgctg agtctgccca gcctggaggc ctacagagac ccctcgtgcc tgagcccggc      600

cagcagcctg tcctcccgga gctgcaactc agaggcctcc tcctacgagt ccaactactc      660

gtacccgtac gcgtcccccc agacgtcgcc atggcagtct ccctgcgtgt ctcccaagac      720

cacggacccc gaggagggct ttccccgcgg gctgggggcc tgcacactgc tgggttcccc      780

gcggcactcc ccctccacct cgccccgcgc cagcgtcact gaggagagct ggctgggtgc      840

ccgctcctcc agacccgcgt ccccttgcaa caagaggaag tacagcctca acggccggca      900

gccgccctac tcaccccacc actcgcccac gccgtccccg cacggctccc cgcgggtcag      960

cgtgaccgac gactcgtggt tgggcaacac cacccagtac accagctcgg ccatcgtggc     1020

cgccatcaac gcgctgacca ccgacagcag cctggacctg ggagatggcg tccctgtcaa     1080

gtcccgcaag accaccctgg agcagccgcc ctcagtggcg ctcaaggtgg agcccgtcgg     1140

ggaggacctg ggcagccccc cgcccccggc cgacttcgcg cccgaagact actcctcttt     1200

ccagcacatc aggaagggcg gcttctgcga ccagtacctg gcggtgccgc agcaccccta     1260

ccagtgggcg aagcccaagc ccctgtcccc tacgtcctac atgagcccga ccctgcccgc     1320

cctggactgg cagctgccgt cccactcagg cccgtatgag cttcggattg aggtgcagcc     1380

caagtcccac caccgagccc actacgagac ggagggcagc cggggggccg tgaaggcgtc     1440

ggccggagga caccccatcg tgcagctgca tggctacttg gagaatgagc cgctgatgct     1500

gcagcttttc attgggacgg cggacgaccg cctgctgcgc ccgcacgcct tctaccaggt     1560

gcaccgcatc acagggaaga ccgtgtccac caccagccac gaggccatcc tctccaacac     1620

caaagtcctg gagatcccac tcctgccgga gaacagcatg cgagccgtca ttgactgtgc     1680

cggaatcctg aaactcagaa actccgacat tgaacttcgg aaaggagaga cggacatcgg     1740

gaggaagaac acacgggtac ggctggtgtt ccgcgttcac gtcccgcaac ccagcggccg     1800

cacgctgtcc ctgcaggtgg cctccaaccc catcgaatgc tcccagcgct cagctcagga     1860

gctgcctctg gtggagaagc agagcacgga cagctatccg gtcgtgggcg ggaagaagat     1920

ggtcctgtct ggccacaact tcctgcagga ctccaaggtc attttcgtgg agaaagcccc     1980

agatggccac catgtctggg agatggaagc gaaaactgac cgggacctgt gcaagccgaa     2040

ttctctggtg gttgagatcc cgccatttcg gaatcagagg ataaccagcc ccgttcacgt     2100

cagtttctac gtctgcaacg ggaagagaaa gcgaagccag taccagcgtt tcacctacct     2160

tcccgccaac gttccaatta taaaaacaga acccactgat gattatgagc ctgctccaac     2220

ctgtggaccg gtgagccagg ggttaagtcc tctcccaaga ccatactaca gccagcagct     2280

cgcgatgcca cccgacccca gctcctgcct cgtggccggc ttcccgccct gtccgcagag     2340

aagcaccctg atgccagcgg cccctggcgt gagccccaag ctccacgacc tttctcccgc     2400

tgcctacacc aagggcgttg ccagcccggg ccactgtcac ctcggactcc cgcagccggc     2460

cggagaggcc cccgccgtcc aggacgtgcc caggccagtg gccacgcacc ccggctcgcc     2520

cgggcagcca cccccggccc tgctgccaca gcaggtgagt gcgcctccaa gcagtagctg     2580

cccccctggt ctcgaacact cgctctgccc cagcagcccc tctcctccac tcccgcctgc     2640

cacccaagag ccgacctgcc tgcagccctg cagcccagcg tgcccgcccg ccacgggccg     2700

cccgcagcac ctgccgtcca cggtccgcag ggacgagtct ccgactgccg ggccacggct     2760

gctgccagag gtgcatgagg acggtagtcc taatttggcc cctattcctg taacggtcaa     2820

gcgagagcct gaagagttgg accagttgta cctggatgac gtaaatgaaa taatacgaaa     2880

tgacctctcc agcacgagca cccactccta gttgccacat tggagcactc agttcagcag     2940

gggtatgctg acttcagcag acaaagactt ttgaataaat aaactgaact cacacctggt     3000

accactcaga acctccaact gactgaatgc caggagctga acattaatat gtgcaaagat     3060

tggctctcca acaagaagga aagcagggag gaagggagac cactgtgtca cctggaggag     3120

aagtcatctc atgacaacag aagggaggtg gccgggctga gcacgggaga cccaccgtgc     3180

aggggccttt catgggaacg gcccacacgc agtttgaccc cacgcccagc ccttctggca     3240

cccctggggt tcaatactgg aagtgcctta tttaaccaga ccatcagggc atcatagaat     3300

tgagcattga atttgctact gtaggagtat ttttaggagc agaaactgca aacacatttc     3360

attgtgaggt tttaccctct gtatgaatga agagaacgct ggaaggctgc gagaggactc     3420

tagtatgagt ctccaacatt tggaacgttt cctgggctgt cacgtacact cctgctgcct     3480

tacacagtgc attttagaat cttccagtct gtcatctcag ctcttttgta acatgcttcc     3540

cttgtctgcg cggttgaaac cgtaggcttg ttcatagtcg catgctcgca tctttgtttt     3600

taatctggct tcgaacatag cacaagtaac ttgaatagca catcaatagg ttactggaca     3660

aaagcagaaa aacctgttac aggatagcct gcatttgcat gtgtgtacat atctaggcat     3720

ctatttatgt ataaataata acagagccga cgtgtcctcg cccaggaggg cttccctgtc     3780

agcaataacc ggcatccgtt ttggaacctg cgtctggggc tccagtcgct gctcttgctg     3840

gcgtccatcg ccgcctcgga cggccgtgca ttttctcgtc tcacgcagtt cgaggaggac     3900

cctagaaagc caggagctgt gattgacagt agctgtaggt taccagacgg caacattaga     3960

aagtgattgt aaataacatg caacctaagt gtaatatatt tgttcagtta taagatgatt     4020

gtttcacaga agccttacca ctctctgctt catctaagaa aaccaatacc aaaaacgcca     4080

ctttaatgct cagccctgcg ttgtgtgttt tcagatgagt tactgttaac aggtaggttt     4140

gtgtaggcct tgctgggcac tctgtacaat tagttgctta ttacgtatga ttactcacag     4200

cgatctattg ttccatataa ccaaaaagca tggtttattc attgaaacac ggttgacctg     4260

aactcgtgcc ttaggaatta atgccccctt atggaacctg cctgaattgc acctgcgggt     4320

ggaggctccg gctgtgaagt cactgaacag aacgtcgctg atggagaaag ggctcccgca     4380

gaaggaacgg cctgtaccgt gcgctccggc acaatcgcgt ctcttgtgtc tcactcacgg     4440

aaagaaacaa cctgaaggcc atcccgtcgg tctgcacgta accgtgaaga cgtgtggccg     4500

cgtcccacct gcggctgggt accctgcacc cggcactgta ggagtcacgt gcagcctttc     4560

tcaggggact gtcattgaaa aggaaacgtt tgatgtctgt gtcagctgtc tttgtagtta     4620

ggaaatagat ccaataaagc cgtatttttt tgctgga                              4657


<210>  2243
<211>  4839
<212>  DNA
<213>  homo sapiens

<400>  2243
agcggccttt ctctgttcgc gatgtgacgt aacgcgcctg cggactgggc ccagcttgtc       60

ctctatgact tacccagaag gcaacgcttc tctttctggt caaaatggct ggtaagcagg      120

ccgtttcagc atcaggcaag tggctggatg gtattcgaaa atggtattac aatgctgcag      180

gattcaataa actggggtta atgcgagatg atacaatata cgaggatgaa gatgtaaaag      240

aagccataag aagacttcct gagaaccttt ataatgacag gatgtttcgc attaagaggg      300

cactggacct gaacttgaag catcagatct tgcctaaaga gcagtggacc aaatatgaag      360

aggaaaattt ctaccttgaa ccgtatctga aagaggttat tcgggaaaga aaagaaagag      420

aagaatgggc aaagaagtaa tcatgtagtt gaagtctgtg gatgcagctg ttatgaagat      480

ggttaaactt gaaacaaaca attttaagaa ttatttggtc tgaagatgtt ttactttaaa      540

taaatgtcta ttgtaatggc tggagttttt gaattccaaa ccttatactg aataactact      600

gaatcccttt actgttaaat ttttttccaa actttcaaga tatatttagt tgtgtttaac      660

tgctacttgg agctcagaag ccactttatc agttttcctc actggttgga tagcctatca      720

gtttatggaa ggatataact tccgtaagtt acatccttat ggaagctact gaataaaaga      780

agggggtatg caccccctag tttgccaaga ttgagaaata gcctcttcac tggtatgcaa      840

acagatttga ttttgcatcc tatcatttaa aaagaaatta tgtctgcacc ccaacatagg      900

catacttaag taatatacat actcctgtgc taacatgtat actagaaaac aaaaagatgt      960

tagaaaaata aaagtataaa gacaaatcat actgtcccca tatcccagtg acttttccac     1020

tttggaaatg attgttatga agtttaaggg ttggatacta gtcagttaaa agttttaaga     1080

ttatagggta atttttaaaa atataaatta gaatcattgg caaggcatgg tggctcatgc     1140

ctgtaatccc agcactttgg gaggccgagg cgggcgggtc acctgaagtc aggaatttga     1200

gaccagcctg gccaacatgg tgaaaccctg tctctactaa aaatacaaaa aattagctag     1260

gcgtgatggt aggcacctgt aatcccagct actcgggagg ctgagggagg agaattgctt     1320

gaccccagga ggtggaggtt gcagtgagcc tagatcacac cactgcactt cagcctgagc     1380

gacattgact gtctcaaaaa aaaaattagg attattcaat gttgtcatca tttccactcc     1440

taaattctga aatgctttct ttggtagagg tgagagtgtg gagccacagc tagtagagaa     1500

ggaacagtag gacctgcagc ctccctggtt ttccaggaca agtcattgct gtgtgtggca     1560

ggaatgcctt acctcaaata acaaaacagt gtgaaaaacg aatttgtgtt acatttaaag     1620

tttgtaaagc aatgagaaat gtgtgtatca taaagagcat ctttaaattt ttgctaaaat     1680

attagcctct taaattctct aggaaccccc tcccccgctt ttttttttcc tttcgctggt     1740

cgttattttt ctaaacctat cctgaaatca tgtcaatttt cttttgtatg gttgaagaca     1800

actagatcac ttgataatgg ttttgctcag gtcacattgt gacaaggttt taatgtagtc     1860

ctactttgca gaaggaggcc aagaagatgg gctgtctaga acccccttta aaagcatttg     1920

tctattcaga aaattttcct gagtagatct ctgcaaaggc tcttttaata gtgatttcaa     1980

gatcacgttt gcaggactct ggtctattcg ttcagacgtc tactgtgcac aattacaagg     2040

agactacaac tgaggcatct caaagagcac tgtcaaggtg tgtagggagc cgggtgggtg     2100

gagggaggct gggctctgac cctagaaacc atgcttatga atgctgttaa tgtttaaagc     2160

aagcctaagg gcactgctga aggacagggg aacaaataga actgaccaag actgaggtat     2220

aacaggaacc cccaggctat ccacctgctc aaggtaaagt gtggtattac ataaggcaac     2280

ctctgatttt gtaagagttc ttcctaaagc caaagtgtat gcctattcta tgtttccaga     2340

ttacttcatt cttctaaatg agaacaagtg tgcaaaagtt ctttgaacac tagatcaatg     2400

ttttgtgttc attataaatt atggttatcg tcctgcttgt tatgaagact aagaaagtag     2460

atctagtatt tggctcacac aggtgaatgg gtgagaattt gttaatccat cagtgaagtc     2520

ctttcatttg aaagagaggg cctttctatt atcaaaagcc gtcctgtgtg gaaaatcacc     2580

atgagagtgc ctgaaacaca ggcactctgc attgtcctgt agaccaaatc tacattgtcc     2640

tgtagtctgg tctacattgt cctgtagacc gaatggtaga gtgattcaga gctaattctg     2700

ggttagactg cacaggtctg aatctatttg ctcactgtgt agtgctttag gaatacaatt     2760

taacctctcc gtgcttcagt ttgtttgtcc ctaagataga gctaatgata gaaacctact     2820

tcacccagtt gtgaaaatta actgactgca tgtcaagcac taacagtttc tggcatatag     2880

tatgcataat gtaaattatg tgctgagaag cgagaaagaa taacttggga aaacgctgaa     2940

tatcatcaat gtcgaatagc taaccagtag ctaaggtcca aggtctcctc tcttccttct     3000

atgtggcact cttgtttctg gttcatctac tccccttggg tgtcacctcc ttgagtgaag     3060

tacctgctgg agatgagaag agtggaactg gatctgcatg acagctttga ttaggatgga     3120

gctaagactt ggctatctcc ctgttttgtg ttttggatgg gtgacatttt aaaactgcca     3180

atattcaaat cctgctaatt tgctttgtac agtttaaaat gtttgatatc ttttgttgtt     3240

taaagtttga gattggtttt gaatatacag ttttcctaca tcttgaagaa agttatgttt     3300

gtttactctg aagtggtcta tgttctgttt gtttgtttta ctatactttg caaaaaaaca     3360

gatggctggc ttatgttcac tgttgtagtg cactacctag tatcacttgg ccttcctgtt     3420

gtcaagatgt aggaagcagc gtaagggatg tcgggccttc agacccccaa ttgccagctg     3480

tggtcctagt tccagattgc atggaaatat ttgataacat tcctgcactg agttatcatg     3540

gtctgaatat ttatgtgacg ctctacgagt ggtaccaaaa tgttagtgat ggagttttta     3600

ctaatggcac cttttcctgt ttttaaattc tagaatctta ataaatccaa agtgtacatt     3660

ttggtagtga tttcatttag ttatttactt taaggactcc cttttcaagc attaactctg     3720

cactaatttt gacttatgaa aagattcagc agtaagaata aaaactgggc caaagcccaa     3780

agtaataatc cttcacaaat aggatggagt tttaaaaata tgggcatcct gtgtgtagct     3840

ttgaaaataa ccaaactact tggaattaaa aagttaggtg aacatgaaga ttgtcataac     3900

caaatccttg acagcttgat ggatgaagag cagatgggtt tatggtgtat gggaggaagc     3960

atggatttta ggagggacag tatcagagag ggatggttag aaagtgagta agacaggttg     4020

ctctttggaa aacaaggaaa atccctttat tagaacaagg catgaaattc tgccactagg     4080

tggcgatgcc ctataacttt acaacttagt gtacatcaca cgagcactat ggaagatttc     4140

tccattctgc gccccaccaa ctccctcccc tccttcattt ttcaggatga caacacctta     4200

gaggtttatg gccatcagga gaatttacta ctaagctata tactgatgta atgaaatcta     4260

atatatgttg tgcaatgaat tatgagatgt tatttagttt caggatttta ttacttcaat     4320

cagttatgac catatttcct tttatatgat tgctcactct ttaaacatac cagatgactg     4380

tataaggaac acctaataaa gtctatagat gttaaaatat tttaaatgtt ttaatttata     4440

tgccataatt tgtttacatt ctggttatac tggcgttcat attaaaagcc ataacatgtt     4500

agaatctgag atctcaggtc ggatagtgcc tctaagttat attttgctaa gaaattttat     4560

tgtattagca attgagcaag aaagaagaac tgaatcatta tacggtggtt aatttttagc     4620

atagatgtca gaaagcctgt taatattcca gaggcttatg ataaactatt taaattgtca     4680

ttctggattc tgattatatc tcctacaaag aaagagtgta ttatttattg aactttttgt     4740

ttgaatacat gtgcctattt ttgcataaat gtaaaaatgt aattttaaaa taaacccctg     4800

aaaacttctg gtaacattaa aaaaaaaaaa aaaaaaaaa                            4839


<210>  2244
<211>  1830
<212>  DNA
<213>  homo sapiens

<400>  2244
ccgcccctca ccaacatggc cgcgggctgg aagtgcgcat gagcagctgt ctatggagat       60

acctaggccg ggagagggag aacacagttg gagaaaatcg gcagctgaga cggccttggc      120

cggacttagc actcaggcct gtgaatcagg agatacaaag acctccaaaa aaggaccagt      180

tcctcggatg tgccccctca cagagagatg aaggggcagc agaaaacagc tgaaacggaa      240

gaggggacag tgcagattca ggaaggtgca gtggctactg gggaagaccc aaccagtgtg      300

gctattgcca gcatccagtc agctgccacc ttccctgacc ccaacgtcaa gtacgtcttc      360

cgaactgaga atgggggcca ggtgatgtac agggtgatcc aggtgtctga ggggcagctg      420

gatggccaaa ctgagggaac tggcgccatc agtggctacc ctgccactca atccatgacc      480

caggcggtga tccagggtgc tttcaccagt gatgatgcag ttgacacgga ggggacagct      540

gctgagacgc actatactta cttccccagc acggcagtgg gagatggggc agggggtacc      600

acatcgggga gtacagctgc tgttgttact acccagggct cagaggcact gctggggcag      660

gcgacccctc ctggcactgg tcaattcttt gtgatgatgt caccacaaga agtactgcag      720

ggaggaagcc agcgctcaat tgcccctagg actcaccctt attccccgaa gtcagaagct      780

ccccggacga ctcgggatga gaaacgcagg gctcagcata atgaagtgga gcgtcgccgc      840

cgagacaaga tcaacaactg gatcgtgcag ctctccaaga taatcccaga ctgctctatg      900

gagagcacca agtctggcca gagtaaaggt gggattctat ccaaagcttg tgattatatc      960

caggagcttc ggcagagtaa ccaccgcttg tctgaagaac tgcagggact tgaccaactg     1020

cagctggaca atgacgtgct tcgacaacag gtggaagatc ttaaaaacaa gaatctgctg     1080

cttcgagctc agttgcggca ccacggatta gaggtcgtca tcaagaatga cagcaactaa     1140

ctatggggat tcaggggctt tgggcccaag aactgcagat agcccaggag caacagccta     1200

atcccgtgcc cctttccttc actgccccac ttctggcatg ggacaggggg aagttcagaa     1260

ggtgtgtcct tgaactgagg ccctgtgata tggcggcctg cagtggtgtg aaacacacaa     1320

tgtggacgtg cactgacagc cttgcccacc cccaccatgc agcccctggg cccttgtgct     1380

cctctcgcac aatgcatgtg ctgtctccat gctggatact ggacacacta aactctgggg     1440

cttgtcctgt gcttgcttag agtgcccagc agaggtttgc tgacaggtga tgctctggct     1500

tgccccagga ctctggcact tccattggtt cttcctttcc ctggagctga ggtttagatg     1560

tgcaacctgt ggctcagggg agcaagctta cacaagaagt gagggaagga tgtttagcag     1620

tggctggtgc ccatgaagag gagattggcc agtgagaagc tgaggcctat gcagacatct     1680

ctggagccag agagaacaac aggcaggggc ccacttgggg ccttccccct tgtgggggtc     1740

gttttttttt tttcttttct tttttttttt tttttttttt tttttttaag ataaaattgt     1800

tcaaagccaa aaaaaaaaaa aaaaaaaaaa                                      1830


<210>  2245
<211>  1465
<212>  DNA
<213>  homo sapiens

<400>  2245
gagcgacgcc cacggcctgt ctcggccacc agcgtgttcc agcgagcgcc cagccacctc       60

gctcgcagcc tccccagcgc agcagcccgg ctgtgggcct gcggcagccg ggtcttcctg      120

gtccccacct cctggggccg acgggcggca ggaaggggct cggcgggacg cgccatcagg      180

gacctgagga ggaacaacgg aacgcgttcg gaacggcctg gactcccgag actcacccga      240

ctcgtggcca caccgggaga actgaagcgg cagtagccgg cggagacgcc cgacccgaag      300

gccggctgct agggagcaga cagctgaacc gcttgccaga cgccgaaacc cagtgacgcc      360

ctccaccgct ccaccgtgct cccggctcct cgcccccgcc gcccgcgggc cccaaggcgc      420

atgcgccgcc tgtcctggag gggcccattt ccgtccgtcg tggggggagg cacagtgagt      480

ccactggggc acggcagcgt ctaagccaca agccgagcac ataagccagg tcctaacgga      540

gcctatgtgt aagtccacta ctggtgcaag gttgcacact tctaagaaga gcggcgtggg      600

gggctcggcg accttcgctt cagtcgctcc cccgtgcagt cccctgtgcc caagacacag      660

cctgatgctt gtgctccggt gggcggagct tggaggcggc gggaactgca attggtggct      720

ttgaaggcgc ggcgagcggg aacagctctt gaggagtgag actgcaggag atgtgggccg      780

tgccaaagag atggatgaga ctgttgctga gttcatcaag aggaccatct tgaaaatccc      840

catgaatgaa ctgacaacaa tcctgaaggc ctgggatttt ttgtctgaaa atcaactgca      900

gactgtaaat ttccgacaga gaaaggaatc tgtagttcag cacttgatcc atctgtgtga      960

ggaaaagcgt gcaagtatca gtgatgctgc cctgttagac atcatttata tgcaatttca     1020

tcagcaccag aaagtttggg aagtttttca gatgagtaaa ggaccaggtg aagatgttga     1080

cctttttgat atgaaacaat ttaaaaattc gttcaagaaa attcttcaga gagcattaaa     1140

aaatgtgaca gtcagcttca gagaaactga ggagaatgca gtctggattc gaattgcctg     1200

gggaacacag tacacaaagc caaaccagta caaacctacc tacgtggtgt actactccca     1260

gactccgtac gccttcacgt cctcctccat gctgaggcgc aatacaccgc ttctgggtca     1320

ggagttagaa gctactggga aaatctacct ccgacaagag gagatcattt tagatattac     1380

cgaaatgaag aaagcttgca attagtgaac atgaaaggaa aataaaaatt cctcacagtc     1440

atctttttaa aaaaaaaaaa aaaaa                                           1465


<210>  2246
<211>  7204
<212>  DNA
<213>  homo sapiens

<400>  2246
gggcaagctg gaaaagcgtg tgggtgagac cctcgcacaa ccccttttca ttgtctgtgt       60

gtggcgcctg cgcagtaagg gatcgttgga actgggcagg aggggatagg gtccggctcc      120

tcgccctttc ccgaggcgcc tgcgcactag gcagtcggtc tttgccgtta ccgctatgtg      180

tggggcgtgt gtggaataac gttattgccc agcggagctg agggccccgg agctcgaccg      240

cagcggcagc gacgacaaca gcggcgacga cgacgacgac gaggtggggg gaggacggcg      300

tgcgagagac tcacgggacg cgacgcgccc cgcctccccc gtccggtccc tctctccacg      360

gtaaggggat gacgtagctt tgccaaagac ttagaagcta agcagaaaat gagcttaaca      420

tcctggtttt tggtgagcag tggaggcact cgccacaggc tgccacgaga aatgattttt      480

gttggaagag atgactgtga gctcatgttg cagtctcgta gtgtggataa gcaacacgct      540

gtcatcaact atgatgcgtc tacggatgag catttagtga aggatttggg cagcctcaat      600

gggacttttg tgaatgatgt aaggattccg gaacagactt atatcacctt gaaacttgaa      660

gataagctga gatttggata tgatacaaat cttttcactg tagtacaagg agaaatgagg      720

gtccctgaag aagctcttaa gcatgagaag tttaccattc agcttcagtt gtcccaaaaa      780

tcttcagaat cagaattatc caaatctgca agtgccaaaa gcatagattc aaaggtagca      840

gacgctgcta ctgaagtgca gcacaaaact actgaagcac tgaaatccga ggaaaaagcc      900

atggatattt ctgctatgcc ccgtggtact ccattatatg ggcagccgtc atggtggggg      960

gatgatgagg tggatgaaaa aagagctttc aagacaaatg gcaaacctga agaaaaaaac     1020

catgaagctg gaacatcagg gtgcggcata gatgccaagc aagttgagga acaatctgca     1080

gctgcaaatg aagaagtact ttttcctttc tgtagggaac caagttattt tgaaatccct     1140

acaaaagaat tccagcaacc atcacaaata acagaaagca ctattcatga aatcccaaca     1200

aaagacacgc caagttccca tataacaggt gcagggcatg cttcatttac cattgaattt     1260

gatgacagta ccccagggaa ggtaactatt agagaccatg tgacaaagtt tacttctgat     1320

cagcgccaca agtccaagaa gtcttctcct ggaactcaag acttgctggg gattcaaaca     1380

ggaatgatgg cacccgaaaa caaagttgct gactggctag cacaaaacaa ccctcctcaa     1440

atgctatggg aaagaacaga agaggattct aaaagcatta aaagtgatgt tccagtgtac     1500

ttgaaaaggt tgaaaggaaa taaacatgat gatggtacgc aaagtgattc agagaacgct     1560

ggggctcaca ggcgctgtag caaacgtgca actcttgagg aacacttaag acgccaccat     1620

tcagaacaca aaaagctaca gaaggtccag gctactgaaa agcatcaaga ccaagctgtt     1680

actagctctg cgcatcacag aggggggcat ggtgttccac atgggaaatt gttaaaacag     1740

aaatcagagg agccatcggt gtcaataccc ttcctacaaa ctgcattatt aagaagttca     1800

gggagtcttg ggcacagacc aagccaggag atggataaaa tgttaaaaaa tcaagcaact     1860

tctgctactt ctgaaaagga taatgatgat gaccaaagtg acaagggtac ttataccatt     1920

gagttagaga atcccaacag tgaggaagtg gaagcaagaa aaatgattga caaggtgttt     1980

ggagtagatg acaatcagga ttataatagg cctgttatca acgaaaaaca taaagatcta     2040

ataaaagatt gggctctcag ttctgctgca gcagtaatgg aagaaagaaa accactgact     2100

acatctggat ttcaccactc agaggaaggc acatcttcat ctggaagcaa acgttgggtt     2160

tcacagtggg ctagtttggc tgccaatcat acaaggcatg atcaagaaga aaggataatg     2220

gaattttctg cacctcttcc tttagagaat gagacagaga tcagtgagtc tggcatgaca     2280

gtgagaagta ctggctctgc aacttccttg gctagccagg gagagagaag gagacgaact     2340

cttccccagc ttccaaatga agaaaagtct cttgagagcc acagagcaaa ggttgtaaca     2400

cagaggtcag agataggaga aaaacaagac acagaacttc aggagaaaga aacacctaca     2460

caggtatacc agaaagataa acaagatgct gacagaccct tgagtaaaat gaacagggca     2520

gtaaatggag agactctcaa aactggtgga gataataaaa ccctacttca cttaggcagc     2580

tctgctcctg gaaaagagaa aagtgaaact gataaggaaa cttctttggt aaagcaaaca     2640

ttagcaaaac ttcaacaaca agaacaaagg gaggaggctc agtggacacc tactaaattg     2700

tcttccaaaa atgtttcagg tcagacagat aaatgtaggg aggaaacttt taaacaagaa     2760

tcacaacctc cagaaaaaaa ttcaggacat tctacaagca aaggagacag agtggcacaa     2820

agtgagagca agagaagaaa agctgaggaa attctgaaaa gtcagactcc aaagggagga     2880

gacaagaagg aatcctccaa gtcattagtg cgacaaggga gcttcactat agaaaaaccc     2940

agcccaaaca tacccataga acttattccc catataaata aacagacttc ctctactcct     3000

tcttctttag cattaacatc tgcaagtaga atacgagaaa gaagtgagtc tttggatcct     3060

gattctagta tggacacaac ccttattcta aaagacacag aagcagtaat ggcttttcta     3120

gaagctaaac tacgtgaaga taataaaact gatgaaggac cagatactcc cagttataat     3180

agagacaatt ctatttcacc agaatctgat gtagatacag ctagtacaat cagtctggtt     3240

actggagaaa ctgaaagaaa gtcaacccaa aagcgaaaga gtttcactag cctctataaa     3300

gataggtgtt ccacaggttc tccttccaaa gatgttacaa aatcatcatc ttcaggtgct     3360

agggaaaaaa tggaaaagaa aacaaaaagt cgttccacag atgtgggttc aagagcagat     3420

ggtcgtaaat ttgttcagtc cagtgggaga ataagacagc cctcagtaga cttaacagat     3480

gatgaccaaa cctctagtgt acctcattct gccatctctg atattatgtc atctgatcaa     3540

gaaacttact cttgtaaacc tcatggacgg actccactta cctcagctga tgagcatgta     3600

cattccaaac tggaaggaag taaagtaacg aaatctaaga cttctccggt ggtatctggt     3660

tcatctagta aatcaaccac ccttccaagg ccacgaccta ccaggacttc cctcttgcgc     3720

agagcacgac ttggtgaagc ttcagacagt gaacttgctg atgctgacaa agcatctgtt     3780

gcttctgaag tatccacaac aagttctaca tcaaaacctc ccacaggaag gcgtaacatc     3840

tctcggattg atttattggc tcagcctcgt agaacacgac ttggctcact gtcagctcgt     3900

agtgactctg aagcaacaat ttctagaagt agtgcctctt cgaggaccgc agaagccatc     3960

attagaagtg gagccagact agtaccatca gataaatttt ctcctagaat tagagctaac     4020

agtatctctc gactctcaga ctccaaggtc aaaagtatga cctcagctca tggctctgct     4080

tcagtaaatt caagatggag gcgctttcct actgattatg cttccacctc agaagatgaa     4140

tttggatcaa accgtaattc ccctaaacat acccgtctac gtacttctcc agccctgaaa     4200

accactcgct tgcagagcgc tggatcagca atgcctacta gttcttcatt caaacaccgg     4260

attaaagagc aggaagacta catccgagat tggactgctc atcgagaaga gatagccagg     4320

atcagccaag atcttgctct cattgctcgg gagatcaacg atgtagcagg agagatagat     4380

tcagtgactt catcaggcac tgcccctagt accacagtaa gcactgctgc caccacccct     4440

ggctctgcca tagacactag agaagagttg gttgatcgtg tttttgatga aagcctcaac     4500

ttccgaaaga ttcctccatt agttcattcc aaaacaccag aaggaaacaa cggtcgatct     4560

ggtgatccaa gacctcaagc agcagagcct cccgatcact taacaattac aaggcggaga     4620

acctggagca gggatgaagt catgggagat aatctgctgc tgtcatccgt ctttcagttc     4680

tctaagaaga taagacaatc tatagataag acagctggaa agatcagaat attatttaaa     4740

gacaaagatc ggaattggga tgacatagaa agcaaattaa gagccgaaag tgaagtccct     4800

attgtgaaaa cctcaagcat ggagatttct tctatcttac aggaactgaa aagagtagaa     4860

aagcagctgc aagcaatcaa tgctatgatt gatcctgatg gaactttgga ggctctgaac     4920

aacatgggat ttcccagtgc tatgttgcca tctccaccga aacagaagtc cagccctgtg     4980

aataaccacc acagcccggg tcagacacca acacttggcc aaccagaagc tagggctctt     5040

catcctgctg ctgtttcagc cgcagctgaa tttgagaatg ctgaatctga ggctgatttc     5100

agtatacatt tcaatagatt caaccccgat ggggaagagg aagatgttac agtacaagaa     5160

tgactttctc ttgattgttg aaaaatcatt acctgtggaa tggctaggaa tattggaagc     5220

agcatagtgt tgatgtacgc aaaacaagac agcttggtca gctacaatct tggaatccct     5280

gtcttcttaa ttttatttat ttatttttga cgtataatgt agtatatcaa tcctttcaaa     5340

ctatttagat aaccacttga tgcacaaata ggaaaaagca gattgtggca gtgtcgcctt     5400

ttgtggtttt atgattttca aattgaattt aatgattaca ccctttccct tcatagatct     5460

tttttctttt ttttaagcca tgctgtgacc tacaagcaaa ctaaatagcc aacatttctg     5520

aacccctaag tctcctgtgc caagctgctc cctgaaatgg acttcttcat ctgtacagat     5580

ttgttaaacc attctatttg cttcttaata ataggattta tattagtact cattaccatt     5640

ggacacaatg acataagtac tctccacagt aaagcagacc tttcacaaca gtcactctgt     5700

gtcctaaaat tttccaacat agatgtgatt tatataactt tgttgatacg taaattgtct     5760

tggggtttac ggaaattaac tattatgttt gcactaagat ttgctgggag tggtaggtgg     5820

acatatctat atatcaataa ggactaaccg tcttttttgt acataggaga ttgataatac     5880

tgtatttgtt ttaagcccac agtgttttac tccactttca aaaagatcaa tttggcactt     5940

tttttcattt tttttaatgg aaataagatt tggtctctca ttttaggtta aatgataact     6000

agaaagatta aactagacag atagtttagg tggagtatat ttttaaaact cagaacatgt     6060

atattggtcc tgtgttacca agtttatatg tgacagttga aaaagaaatt cccttgaaat     6120

gatcatgagg ttaaaatttt cttcattagg ggacttggag aaccagtagt cgtaagatta     6180

gttgatagtt tcactcccaa gcaatgaatt gcttctgtgt gtttccctgt aggactcaat     6240

agtaaatgct gtctgtctta cacatttata aggaccctgc aagacgacga caaaggcctt     6300

tggcctgtgc tactaaacaa gaagcctatg aaaaatttct tctttaaact tgttttttct     6360

ctttccagta agttcacatt tggataattt taaaaagaaa agtaattacc tttgtgtttc     6420

cagaacacta taattggggt gtatcttaat tcagttaaat attattagta gacctggatt     6480

ttcccccttg accccatcag tctataaagg ttaaactgca acttttatga aatggtcttt     6540

aatatttcca caataatcct gtgctatatt tgttttaaga aacaaagtaa ctctatacac     6600

ttcaagactt tacaggattt tttaaatcct gtattgttgg atcaattaat aaagatgcaa     6660

aaaaacttta tagagatgta aaaacaaaac tataatggat ctcctatttt tctttaaata     6720

caaaaaaaaa aaggtaaatg aactattctc cttgtaaagc taaattcccc attctgtcta     6780

ataaaggaag actgaaaaaa ggttttaaag aacataaatg gaaagataca aatgctttga     6840

aggaataaac gaaatgttaa aacagggtca atccatttga agaaaaagtt ggacaaaata     6900

atcagcattg ctccctcttt tatttaatat ttgggtactg attatatcca catggaagta     6960

gaaggtaagg agtttaggaa aatactagaa tctactctgc ttacattctt gtttaagtgt     7020

ttacacagtt tggttcaatt ataaacattt ggccttttac tatgttattt ttattttgta     7080

tgaatacatt atcctcctta tttatttttg ttacatttat tacttatgtt attttgttat     7140

gcatttacaa ctccattttt aaataaagtg tttctggaac tttaaaaaaa aaaaaaaaaa     7200

aaaa                                                                  7204


<210>  2247
<211>  6910
<212>  DNA
<213>  homo sapiens

<400>  2247
gggcaagctg gaaaagcgtg tgggtgagac cctcgcacaa ccccttttca ttgtctgtgt       60

gtggcgcctg cgcagtaagg gatcgttgga actgggcagg aggggatagg gtccggctcc      120

tcgccctttc ccgaggcgcc tgcgcactag gcagtcggtc tttgccgtta ccgctatgtg      180

tggggcgtgt gtggaataac gttattgccc agcggagctg agggccccgg agctcgaccg      240

cagcggcagc gacgacaaca gcggcgacga cgacgacgac gaggtggggg gaggacggcg      300

tgcgagagac tcacgggacg cgacgcgccc cgcctccccc gtccggtccc tctctccacg      360

gtaaggggat gacgtagctt tgccaaagac ttagaagcta agcagaaaat gagcttaaca      420

tcctggtttt tggtgagcag tggaggcact cgccacaggc tgccacgaga aatgattttt      480

gttggaagag atgactgtga gctcatgttg cagtctcgta gtgtggataa gcaacacgct      540

gtcatcaact atgatgcgtc tacggatgag catttagtga aggatttggg cagcctcaat      600

gggacttttg tgaatgatgt aaggattccg gaacagactt atatcacctt gaaacttgaa      660

gataagctga gatttggata tgatacaaat cttttcactg tagtacaagg agaaatgagg      720

gtccctgaag aagctcttaa gcatgagaag tttaccattc agcttcagtt gtcccaaaaa      780

tcttcagaat cagaattatc caaatctgca agtgccaaaa gcatagattc aaaggtagca      840

gacgctgcta ctgaagtgca gcacaaaact actgaagcac tgaaatccga ggaaaaagcc      900

atggatattt ctgctatgcc ccgtggtact ccattatatg ggcagccgtc atggtggggg      960

gatgatgagg tggatgaaaa aagagctttc aagacaaatg gcaaacctga agaaaaaaac     1020

catgaagctg gaacatcagg gtgcggcata gatgccaagc aagttgagga acaatctgca     1080

gctgcaaatg aagaagtact ttttcctttc tgtagggaac caagttattt tgaaatccct     1140

acaaaagaat tccagcaacc atcacaaata acagaaagca ctattcatga aatcccaaca     1200

aaagacacgc caagttccca tataacaggt gcagggcatg cttcatttac cattgaattt     1260

gatgacagta ccccagggaa ggtaactatt agagaccatg tgacaaagtt tacttctgat     1320

cagcgccaca agtccaagaa gtcttctcct ggaactcaag acttgctggg gattcaaaca     1380

ggaatgatgg cacccgaaaa caaagttgct gactggctag cacaaaacaa ccctcctcaa     1440

atgctatggg aaagaacaga agaggattct aaaagcatta aaagtgatgt tccagtgtac     1500

ttgaaaaggt tgaaaggaaa taaacatgat gatggtacgc aaagtgattc agagaacgct     1560

ggggctcaca ggcgctgtag caaacgtgca actcttgagg aacacttaag acgccaccat     1620

tcagaacaca aaaagctaca gaaggtccag gctactgaaa agcatcaaga ccaagctgtt     1680

gtgtttggag tagatgacaa tcaggattat aataggcctg ttatcaacga aaaacataaa     1740

gatctaataa aagattgggc tctcagttct gctgcagcag taatggaaga aagaaaacca     1800

ctgactacat ctggatttca ccactcagag gaaggcacat cttcatctgg aagcaaacgt     1860

tgggtttcac agtgggctag tttggctgcc aatcatacaa ggcatgatca agaagaaagg     1920

ataatggaat tttctgcacc tcttccttta gagaatgaga cagagatcag tgagtctggc     1980

atgacagtga gaagtactgg ctctgcaact tccttggcta gccagggaga gagaaggaga     2040

cgaactcttc cccagcttcc aaatgaagaa aagtctcttg agagccacag agcaaaggtt     2100

gtaacacaga ggtcagagat aggagaaaaa caagacacag aacttcagga gaaagaaaca     2160

cctacacagg tataccagaa agataaacaa gatgctgaca gacccttgag taaaatgaac     2220

agggcagtaa atggagagac tctcaaaact ggtggagata ataaaaccct acttcactta     2280

ggcagctctg ctcctggaaa agagaaaagt gaaactgata aggaaacttc tttggtaaag     2340

caaacattag caaaacttca acaacaagaa caaagggagg aggctcagtg gacacctact     2400

aaattgtctt ccaaaaatgt ttcaggtcag acagataaat gtagggagga aacttttaaa     2460

caagaatcac aacctccaga aaaaaattca ggacattcta caagcaaagg agacagagtg     2520

gcacaaagtg agagcaagag aagaaaagct gaggaaattc tgaaaagtca gactccaaag     2580

ggaggagaca agaaggaatc ctccaagtca ttagtgcgac aagggagctt cactatagaa     2640

aaacccagcc caaacatacc catagaactt attccccata taaataaaca gacttcctct     2700

actccttctt ctttagcatt aacatctgca agtagaatac gagaaagaag tgagtctttg     2760

gatcctgatt ctagtatgga cacaaccctt attctaaaag acacagaagc agtaatggct     2820

tttctagaag ctaaactacg tgaagataat aaaactgatg aaggaccaga tactcccagt     2880

tataatagag acaattctat ttcaccagaa tctgatgtag atacagctag tacaatcagt     2940

ctggttactg gagaaactga aagaaagtca acccaaaagc gaaagagttt cactagcctc     3000

tataaagata ggtgttccac aggttctcct tccaaagatg ttacaaaatc atcatcttca     3060

ggtgctaggg aaaaaatgga aaagaaaaca aaaagtcgtt ccacagatgt gggttcaaga     3120

gcagatggtc gtaaatttgt tcagtccagt gggagaataa gacagccctc agtagactta     3180

acagatgatg accaaacctc tagtgtacct cattctgcca tctctgatat tatgtcatct     3240

gatcaagaaa cttactcttg taaacctcat ggacggactc cacttacctc agctgatgag     3300

catgtacatt ccaaactgga aggaagtaaa gtaacgaaat ctaagacttc tccggtggta     3360

tctggttcat ctagtaaatc aaccaccctt ccaaggccac gacctaccag gacttccctc     3420

ttgcgcagag cacgacttgg tgaagcttca gacagtgaac ttgctgatgc tgacaaagca     3480

tctgttgctt ctgaagtatc cacaacaagt tctacatcaa aacctcccac aggaaggcgt     3540

aacatctctc ggattgattt attggctcag cctcgtagaa cacgacttgg ctcactgtca     3600

gctcgtagtg actctgaagc aacaatttct agaagtagtg cctcttcgag gaccgcagaa     3660

gccatcatta gaagtggagc cagactagta ccatcagata aattttctcc tagaattaga     3720

gctaacagta tctctcgact ctcagactcc aaggtcaaaa gtatgacctc agctcatggc     3780

tctgcttcag taaattcaag atggaggcgc tttcctactg attatgcttc cacctcagaa     3840

gatgaatttg gatcaaaccg taattcccct aaacataccc gtctacgtac ttctccagcc     3900

ctgaaaacca ctcgcttgca gagcgctgga tcagcaatgc ctactagttc ttcattcaaa     3960

caccggatta aagagcagga agactacatc cgagattgga ctgctcatcg agaagagata     4020

gccaggatca gccaagatct tgctctcatt gctcgggaga tcaacgatgt agcaggagag     4080

atagattcag tgacttcatc aggcactgcc cctagtacca cagtaagcac tgctgccacc     4140

acccctggct ctgccataga cactagagaa gagttggttg atcgtgtttt tgatgaaagc     4200

ctcaacttcc gaaagattcc tccattagtt cattccaaaa caccagaagg aaacaacggt     4260

cgatctggtg atccaagacc tcaagcagca gagcctcccg atcacttaac aattacaagg     4320

cggagaacct ggagcaggga tgaagtcatg ggagataatc tgctgctgtc atccgtcttt     4380

cagttctcta agaagataag acaatctata gataagacag ctggaaagat cagaatatta     4440

tttaaagaca aagatcggaa ttgggatgac atagaaagca aattaagagc cgaaagtgaa     4500

gtccctattg tgaaaacctc aagcatggag atttcttcta tcttacagga actgaaaaga     4560

gtagaaaagc agctgcaagc aatcaatgct atgattgatc ctgatggaac tttggaggct     4620

ctgaacaaca tgggatttcc cagtgctatg ttgccatctc caccgaaaca gaagtccagc     4680

cctgtgaata accaccacag cccgggtcag acaccaacac ttggccaacc agaagctagg     4740

gctcttcatc ctgctgctgt ttcagccgca gctgaatttg agaatgctga atctgaggct     4800

gatttcagta tacatttcaa tagattcaac cccgatgggg aagaggaaga tgttacagta     4860

caagaatgac tttctcttga ttgttgaaaa atcattacct gtggaatggc taggaatatt     4920

ggaagcagca tagtgttgat gtacgcaaaa caagacagct tggtcagcta caatcttgga     4980

atccctgtct tcttaatttt atttatttat ttttgacgta taatgtagta tatcaatcct     5040

ttcaaactat ttagataacc acttgatgca caaataggaa aaagcagatt gtggcagtgt     5100

cgccttttgt ggttttatga ttttcaaatt gaatttaatg attacaccct ttcccttcat     5160

agatcttttt tctttttttt aagccatgct gtgacctaca agcaaactaa atagccaaca     5220

tttctgaacc cctaagtctc ctgtgccaag ctgctccctg aaatggactt cttcatctgt     5280

acagatttgt taaaccattc tatttgcttc ttaataatag gatttatatt agtactcatt     5340

accattggac acaatgacat aagtactctc cacagtaaag cagacctttc acaacagtca     5400

ctctgtgtcc taaaattttc caacatagat gtgatttata taactttgtt gatacgtaaa     5460

ttgtcttggg gtttacggaa attaactatt atgtttgcac taagatttgc tgggagtggt     5520

aggtggacat atctatatat caataaggac taaccgtctt ttttgtacat aggagattga     5580

taatactgta tttgttttaa gcccacagtg ttttactcca ctttcaaaaa gatcaatttg     5640

gcactttttt tcattttttt taatggaaat aagatttggt ctctcatttt aggttaaatg     5700

ataactagaa agattaaact agacagatag tttaggtgga gtatattttt aaaactcaga     5760

acatgtatat tggtcctgtg ttaccaagtt tatatgtgac agttgaaaaa gaaattccct     5820

tgaaatgatc atgaggttaa aattttcttc attaggggac ttggagaacc agtagtcgta     5880

agattagttg atagtttcac tcccaagcaa tgaattgctt ctgtgtgttt ccctgtagga     5940

ctcaatagta aatgctgtct gtcttacaca tttataagga ccctgcaaga cgacgacaaa     6000

ggcctttggc ctgtgctact aaacaagaag cctatgaaaa atttcttctt taaacttgtt     6060

ttttctcttt ccagtaagtt cacatttgga taattttaaa aagaaaagta attacctttg     6120

tgtttccaga acactataat tggggtgtat cttaattcag ttaaatatta ttagtagacc     6180

tggattttcc cccttgaccc catcagtcta taaaggttaa actgcaactt ttatgaaatg     6240

gtctttaata tttccacaat aatcctgtgc tatatttgtt ttaagaaaca aagtaactct     6300

atacacttca agactttaca ggatttttta aatcctgtat tgttggatca attaataaag     6360

atgcaaaaaa actttataga gatgtaaaaa caaaactata atggatctcc tatttttctt     6420

taaatacaaa aaaaaaaagg taaatgaact attctccttg taaagctaaa ttccccattc     6480

tgtctaataa aggaagactg aaaaaaggtt ttaaagaaca taaatggaaa gatacaaatg     6540

ctttgaagga ataaacgaaa tgttaaaaca gggtcaatcc atttgaagaa aaagttggac     6600

aaaataatca gcattgctcc ctcttttatt taatatttgg gtactgatta tatccacatg     6660

gaagtagaag gtaaggagtt taggaaaata ctagaatcta ctctgcttac attcttgttt     6720

aagtgtttac acagtttggt tcaattataa acatttggcc ttttactatg ttatttttat     6780

tttgtatgaa tacattatcc tccttattta tttttgttac atttattact tatgttattt     6840

tgttatgcat ttacaactcc atttttaaat aaagtgtttc tggaacttta aaaaaaaaaa     6900

aaaaaaaaaa                                                            6910


<210>  2248
<211>  3875
<212>  DNA
<213>  homo sapiens

<400>  2248
ccctcggtgc gcgggcacag cagccaggct gccggagagc tgatctcggg gattcgggtg       60

cggagccctt ggcctggagg cgatatgggt ggtccgtggc ccggttcagt cgcttgcagc      120

agcccgggga acaggcctgt ctggccctga gggagtcccc tttctgaagc tgtggtgctt      180

ggacgacctg ctctctacat tgctgggcac ctgtaggtgt ccctcgagag ctcagttttg      240

aggttcaagt cagtgtggcc atgaaggggc tgcctattgg gctgatgctg tgaccctgga      300

gtctgcctct cctgccagtc cccctgcccg gaacatgtgg ctgcggcttg gcccgccctc      360

gctgtccctg agccccaagc ccacggttgg caggagcctg tgcctcaccc tgtggttcct      420

cagtttggcg ctgagggcca gtacccaggc cccagcaccc acagtcaaca ctcactttgg      480

gaagctaagg ggtgcccgag taccactgcc cagtgagatc ctggggcctg tggaccaata      540

cctgggggtg ccctacgcag ctcccccgat cggcgagaaa cgtttcctgc cccctgaacc      600

acccccatcc tggtcgggca tccggaacgc cacacacttt cccccagtgt gcccccagaa      660

catccacaca gctgtgcccg aagtcatgct gccggtctgg ttcactgcca acttggatat      720

cgtcgctact tacatccagg agcccaacga agactgtctc tacctgaacg tctatgtgcc      780

gacggaggat gacatccggg acagtggtgc taaacccgtc atggtctaca tccacggagg      840

ctcttacatg gaagggacag gcaacatgat tgatggcagc atcctcgcca gttatggcaa      900

tgtcatcgtc atcaccctca actatcgggt tggagtgcta ggtttcctga gtactggaga      960

tcaggctgcc aagggcaact atgggctcct tgaccagatc caggccctcc gctgggtgag     1020

cgagaatatt gccttcttcg ggggagaccc ccgccggatc actgtctttg gctcgggcat     1080

tggtgcatcc tgcgtcagcc tcctcacgtt gtcacatcac tcagagggac ttttccagag     1140

agccatcatc caaagtggct ctgctctgtc cagctgggct gtgaactacc aaccagtgaa     1200

gtacaccagc ctgctggcag acaaagtggg ctgtaatgtg ctggacaccg tggatatggt     1260

ggactgtctt cggcaaaaga gtgccaagga gctggtagag caggacatcc agccagcccg     1320

ctaccacgtg gcctttggcc ctgtgattga tggtgatgtc attcctgatg accctgagat     1380

cctcatggag cagggcgagt tcctcaacta tgacatcatg ctaggtgtca accagggcga     1440

gggtctcaag tttgtggaag gggtggtgga ccctgaggat ggtgtctctg gcactgactt     1500

tgactattcc gtctccaatt ttgtggacaa tctgtatggc tatcctgagg gtaaggacac     1560

cctgcgagag accatcaagt tcatgtatac agactgggca gaccgtgaca accctgagac     1620

ccgccgtaaa acactggtgg cactcttcac tgaccaccag tgggtggagc cctcagtggt     1680

gacagccgat ctgcatgccc gctacggctc gcctacctac ttctacgcct tctatcatca     1740

ctgccagagc ctcatgaagc ctgcttggtc agatgcagct catggggatg aagtacccta     1800

tgtttttggg gttcctatgg taggccccac tgaccttttc ccctgcaact tctccaagaa     1860

tgatgttatg ctcagtgctg tcgtcatgac ctattggacc aactttgcca agactgggga     1920

tcccaacaag ccggtccccc aggacaccaa gttcattcac accaaggcca accgctttga     1980

ggaagtggcc tggtccaaat acaatccccg agaccagctc taccttcaca tcgggctgaa     2040

accaagggtc cgagatcatt accgggccac taaggtggcc ttttggaaac atctggtgcc     2100

ccacctatac aacctgcatg acatgttcca ctatacgtcc accaccacca aagtgccgcc     2160

tccggatacc acccacagct cccacatcac ccgcaggccc aatggcaaga cctggagcac     2220

caagcggcca gccatctcac ctgcctacag caacgagaat gcccaggggt cctggaacgg     2280

ggaccaggat gcagggccac tcctggtgga gaaccctcgt gactactcca ctgaattaag     2340

tgtcaccatc gccgtggggg cctccctcct gttccttaac gttctggcct tcgctgccct     2400

ctactaccgt aaggacaaac ggcgccagga gcccctgcgg cagcctagcc ctcagcgggg     2460

agccggggcc ccggagttgg gagctgctcc agaggaggag ctggcagcat tacaactggg     2520

ccccacccac cacgagtgtg aggccggtcc cccccatgac acgctgcgcc tcactgcatt     2580

gcccgactac accctgaccc tgcggcgctc cccggatgac atcccactca tgacccccaa     2640

caccatcact atgatcccca actccctggt agggctgcag acattgcacc cctataacac     2700

ctttgccgca gggttcaaca gtaccgggct gccccactca cactccacta cccgggtata     2760

gctccaactc agagcacagc caatctccag gctccctccc tcccagatcc aggaacacat     2820

gcacacacac acacacacac acgcagacac acacacacac acacatatat gtatacgcac     2880

gcacccacac cctacagcag atccacctgc acaaacatag acagatgtgg acatgcaccc     2940

gcatgtacaa aaacacaaat acggaagtaa acctgaacaa accctttaaa tggggacgca     3000

gatgagtcct cggtaaaccg aggacccatg aaacagcagc tgaagccagc tccctgaatc     3060

tgaccacaga cactcctggg gggcctgaaa gcaacagctg gacaccccct tggtgctcgc     3120

cttcggcctc tcttggaact gcaccaccga ccaactccag acttgggagc tttaaagagc     3180

aggatagctc ttcctcccca ggacttggtc ttttttctgg gtcttgtttt gttgattttt     3240

cttttttaat tttggaacaa atgcttttcc aacccatgag tgctaagagc ctctggaagg     3300

gagggcttca ggcccgaagg tctctctggc tctaggaccc ccagtgctca cacaatcaga     3360

ccaaggaaca agacccccag gaaggaaaca gatttaagca agaccatggg gtggaaggag     3420

aaaggggcta gcactggatg gagctggagg gtcgtagggg agagatctcc aactctctct     3480

gtgtccgtgt ggagggctgc agagcctgca gggtgacctg cttccccaaa ggccaacagc     3540

attggcctgg ccagaccagg tgaccttaga tttggtgaac aacgtactat ggaagccaca     3600

tcactattgg gcccccaggt ctgatctggg ttttgcctct gcccttgggg aaatgctatc     3660

agaaattcgc cccattttct ttacagtctt ttgtgtctgt catttctctt tcaaaaaggc     3720

ggtgtttttt gttgttgttg gttttttttt ttttttaaag aaaagttctt aaaacactaa     3780

cggaaaccca tggagtttgt cctttgtaaa aattttaaac acagtgtctt gatataaaaa     3840

taaaaaatcc agttagcact cccaaaaaaa aaaaa                                3875


<210>  2249
<211>  3200
<212>  DNA
<213>  homo sapiens

<400>  2249
ccatactgaa gccctcccaa gtgcagcctt gcgggcctcg cagagagcgc caaaccatcc       60

ggccctgcgc gccacgcgga ccggcatagc catctctctg gagtggcagc tgtgccaagg      120

tggcaaggtt aggcccgcag gccctcagca cgggggcgca gccggggcaa gtcttcagga      180

agcagcgagg tgcttgaagg gggtgctgga ggcaggccaa acccagtcag gatgggtggc      240

ctggggccac gacgggcggg aacctcgagg gagaggctag tggtaacagg ccgagctgga      300

tggatgggta tggggagagg ggcaggacgt tcagccctgg gattctggcc gaccctcgcc      360

ttccttctct gcagcttccc cgcagccacc tccccgtgca agatcctcaa gtgcaactct      420

gagttctgga gcgccacgtc gggcagccac gccccagcct cagacgacac ccccgagttc      480

tgtgcagcct tgcgcagcta cgccctgtgc acgcggcgga cggcccgcac ctgccggggt      540

gacctggcct accactcggc cgtccatggc atagaggacc tcatgagcca gcacaactgc      600

tccaaggatg gccccacctc gcagccacgc ctgcgcacgc tcccaccggc cggagacagc      660

caggagcgct cggacagccc cgagatctgc cattacgaga agagctttca caagcactcg      720

gccaccccca actacacgca ctgtggcctc ttcggggacc cacacctcag gactttcacc      780

gaccgcttcc agacctgcaa ggtgcagggc gcctggccgc tcatcgacaa taattacctg      840

aacgtgcagg tcaccaacac gcctgtgctg cccggctcag cggccactgc caccagcaag      900

ctcaccatca tcttcaagaa cttccaggag tgtgtggacc agaaggtgta ccaggctgag      960

atggacgagc tcccggccgc cttcgtggat ggctctaaga acggtgggga caagcacggg     1020

gccaacagcc tgaagatcac tgagaaggtg tcaggccagc acgtggagat ccaggccaag     1080

tacatcggca ccaccatcgt ggtgcgccag gtgggccgct acctgacctt tgccgtccgc     1140

atgccagagg aagtggtcaa tgctgtggag gactgggaca gccagggtct ctacctctgc     1200

ctgcggggct gccccctcaa ccagcagatc gacttccagg ccttccacac caatgctgag     1260

ggcaccggtg cccgcaggct ggcagccgcc agccctgcac ccacagcccc cgagaccttc     1320

ccatacgaga cagccgtggc caagtgcaag gagaagctgc cggtggagga cctgtactac     1380

caggcctgcg tcttcgacct cctcaccacg ggcgacgtga acttcacact ggccgcctac     1440

tacgcgttgg aggatgtcaa gatgctccac tccaacaaag acaaactgca cctgtatgag     1500

aggactcggg acctgccagg cagggcggct gcggggctgc ccctggcccc ccggcccctc     1560

ctgggcgccc tcgtcccgct cctggccctg ctccctgtgt tctgctagac gcgtagatgt     1620

ggagggaggc gcgggctccg tcctctcggc ttccccatgt gtgggctggg accgcccacg     1680

gggtgcagat ctcctggcgt gtccaccatg gccccgcaga acgccaggga ccgcctgctg     1740

ccaagggctc aggcacggac ccctcccctt ctagtgcacg tgacaaggtt gtggtgactg     1800

gtgccatgat gtttgacagt agagctgtgt gagagggaga gcagctcccc tcgccccgcc     1860

cctgcagtgt gaatgtgtga aacatcccct caggctgaag ccccccaccc ccaccagaga     1920

cacactggga accgtcagag tcagctcctt ccccctcgca atgcactgaa aggcccggcc     1980

gactgctgct cgccgatccg tggggccccc tgtgcccgcc acacgcacgc acacactctt     2040

acacgagagc acactcgatc cccctaggcc agcggggaca ccccagccac acagggaggc     2100

atccttgggg cttggcccca ggcagggcaa ccccggggcg ctgcttggca ccttagcaga     2160

ctgctggaac cttttggcca gtaggtcgtg cccgcctggt gccttctggc ctgtggcctc     2220

cctgcccatg ttcacctggc tgctgtgggt accagtgcag gtcccggttt tcaggcacct     2280

gctcagctgc ccgtctctgg cctgggcccc tgccccttcc accctgtgct tagaaagtcg     2340

aagtgcttgg ttctaaatgt ctaaacagag aagagatcct tgacttctgt tcctctctct     2400

cctgcagatg caagagctcc tgggcagggg tgcctgggcc ccagggtgtg gcaggagacc     2460

cagtggatgg ggccagctgg cctgccctga tcctctgctt cctcctcaca accccaagag     2520

cccccagccc ggtccatcca cgtctggagt ctggggagag gagcagggtc ttaggactct     2580

cagctctgag catccctggc agggtcttca acctctaatc tcttccctta agccctgtgg     2640

ccacacagcc aggagagact tgccgctggc tcccgcctca tttcagccca gggtgctcat     2700

ccaggggccc agaacagtcc cacctgtgct gctgtgccca cagcacaaag ccaggcttca     2760

ctcccaaaag tgcagccagg ccctggaggg tgatcctgcc agcagcccta cagctccaca     2820

ccctacccac ccatcggcag cccctctgct gttccccagg gacctctcat acactggcca     2880

ggaggctgca gaacgtgtgt ctccccctcc ctccaagagg tcctgctccc tctgccagaa     2940

ccgtgtgtgg gcgggtggga gggcgctcgg ggcccggccc ctccctctcc ctgctggttt     3000

tagttggtcc ctatgttgga agtaaaaagt gaagcacttt attttggttg tgtttgctca     3060

cgttctgctt ggaagtgggg acccctcact gcgtccacgt gtctgcgacc tgtgtggagt     3120

gtcaccgcgt gtacatactg taaattattt attaatggct aaatgcaagt aaagtttggt     3180

ttttttgtta ttttctttta                                                 3200


<210>  2250
<211>  4312
<212>  DNA
<213>  homo sapiens

<400>  2250
ggccccaacg cgggcttagc ctcccgcctt ggctcgggca ggcgcccgtc gacccttcgg       60

cccctttcgc ccgccctgga gctgggggca gggtgccagt ggaagcgtgg ggcttggctc      120

tgtgattcat tcattctccg ccgacgggag cctcagaccc gctgtgctct gaagagagga      180

gggaagaggg ggcagccgcg aatgaagggc cgggcaccag ccgggctcca ttgtgctcgg      240

cggcgggggg cgggaagggg ctgagggagg tgggatcggg tcccctcctc cagctctccg      300

gcgtgcgctg cgcccccagc ctgctgccag cctggaaatg gctccgttta ttctcttcgg      360

gagaatgaat cgatcctgcc tagccttctc ttcgtcctcc ccacctcttc tctgctccga      420

gtcttaggag gagaaacatt taaaaagaca gattccaatg tggagtgccg tgcaggttgc      480

gagctgccgg gtttgcactt cgaggagatt ttcctgtgta gtttttttcc taatgtgagc      540

gcagggaagc cgtggcatta ctgcttttgg gatttttatt cacgtgcacg tcgcgtttgg      600

ttgctcgctc cacccccgga gacctggtgt ggtggagaaa tttgaacccg cagccttagc      660

tccgaaaagg ccgagttacc tggctctccc tgagtgtcga ggaggacatg agtgaaatga      720

ccagcgaact cattttttat aggactcggt gaagccggat tctgcatttc cctacttgta      780

gactcatttt gtggaataga gttgatcgct gtctcctccg caaagcattt taactcgaat      840

aagcaaatgc cgcctctgtt tgaacgtttt ggtatttaca agagagaaat cattttacct      900

aagagaacta attgaattgg cagcatcctt gaaatacctc cggacaagga tctgggggtg      960

ggggtggaaa agcaactgcg aaatagcaga cggagaaatt cctttggaag ttattccgta     1020

gcataagagc tgaaacttca gagcaagttt tcattgggca aaatggggga acaacctatc     1080

ttcagcactc gagctcatgt cttccaaatt gacccaaaca caaagaagaa ctgggtaccc     1140

accagcaagc atgcagttac tgtgtcttat ttctatgaca gcacaagaaa tgtgtatagg     1200

ataatcagtt tagatggctc aaaggcaata ataaatagta ccatcacccc aaacatgaca     1260

tttactaaaa catctcagaa gtttggccag tgggctgata gccgggcaaa caccgtttat     1320

ggattgggat tctcctctga gcatcatctt tcgaaatttg cagaaaagtt tcaggaattt     1380

aaagaagctg ctcgactagc aaaggaaaaa tcacaagaga agatggaact taccagtaca     1440

ccttcacagg aatccgcagg cggggatctt cagtctcctt taacaccgga aagtatcaac     1500

gggacagatg atgaaagaac acctgatgtg acacagaact cagagccaag ggctgaacca     1560

actcagaatg cattgccatt ttcacatagt tcagcaatca gcaaacattg ggaggctgaa     1620

ctggctaccc tcaaaggaaa taatgccaaa ctcactgcag ccctgctgga gtccactgcc     1680

aatgtgaaac aatggaaaca gcaacttgct gcctatcaag aggaagcaga acgtctgcac     1740

aagcgggtga ctgaacttga atgtgttagt agccaagcaa atgcagtaca tactcataag     1800

acagaattaa atcagacaat acaagaactg gaagagacac tgaaactgaa ggaagaggaa     1860

atagaaaggt taaaacaaga aattgataat gccagagaac tacaagaaca gagggattct     1920

ttgactcaga aactacagga agtagaaatt cggaacaaag acctggaggg acaactgtct     1980

gacttagagc aacgtctgga gaaaagtcag aatgaacaag aagcttttcg caataacctg     2040

aagacactct tagaaattct ggatggaaag atatttgaac taacagaatt acgagataac     2100

ttggccaagc tactagaatg cagctaagga aagtgaaatt tcagtgccaa ttaattaaaa     2160

gatacactgt ctctcttcat aggactgttt aggctctgca tcaagattgc acaaaaaaaa     2220

aaaaaaaaaa attgaatatc actcctccag gaggaggatc ttttgaaatt ggaattgtat     2280

atttcactgt aaattttaga atccagcttg tagctagttg gggaaaaaag atgaaaaact     2340

tgaactacaa attacctcca tgtatattat tggccatagt taactagaaa gttataaata     2400

gacacttaat gcaatctttt ttcctgatat tagccaatgg gagaattaac aatgtctagg     2460

tcacatcccc tttttgtgtt caacacagtg aagattatct gctttttaaa ttaatttatt     2520

tacgatatct agagctgtgt tttgtgcaaa aacttagtga tgaaagcctg tcttttgttg     2580

taatctgaat aatttctcag gatatttttg cactgctgag aagcagtgcc attaccaatt     2640

aattcttgcc aggagtgaga gagagctgta tctttaattg aaatatacta taactgggtg     2700

tatagagttc ttcccttttt tgtgctggaa gatatttcac tctggtgact actctggtac     2760

actctggtgt tctctaatct tgtctgttgt atagtttact tttccatatt gattccatgt     2820

atttatgaga agatattgtc tcccatttta ttacacattt taaagccaac taacgaaggc     2880

agctgagtcc ctcagaaatt tttcttttta agtttctaat aaatttgaca cacagtactg     2940

aaatacagca gcccgtcatt gacaggctgg tctagcaatg ttaagtatat ttacagaata     3000

tgcagttaca tttatttata tattttgcaa gaaatctttt ctgaatgatc aatgcatttc     3060

aatttacgaa taataatggt tattggggaa ctgtttatta tagataattt taaggtgtat     3120

agctatttta aagggggtcc atttacatca aacagctgat cagaggactc tatctaaatt     3180

gtgatcgtgg cagatagaga tggagtcatg tactctatct ggctctacac atcaatcaca     3240

tcttgattca aacctcacaa ggcaatattc tgaattgtta actaggtatt tcaaaacagg     3300

aattaaattc aataggctct tctcagtgaa caggttttaa tgttgttttg atgtaatttt     3360

aaaagacttt tagcaaacat gcatttcttt atatgatata tttcttttac gaagctattt     3420

taaaagtaag ccaagtgctg tctagtctgc ttataaagta ggaattgcat cagagtacat     3480

atattcttgc tgtacaatgc ctgtgatgtt gaggagggtt cttttttaaa gtgtatgctt     3540

gagtaactga ctctatggag tctataaatg cactgacttc ttgtttgtac cccaaaatga     3600

tcgaattgtt aagtacaaaa ttaagctaat taaccaattt gtaaccattt tttcactcat     3660

aaacagctac tcaatactag acaattttgt tttttatgta tgtgtatgta cgtaaataca     3720

tacatattaa tttacattag agtgaaaaat aaatggtttg tttctgaagt tagtttctta     3780

agtgagtttt caggtgtctc tgaaaaattt ataacaatca tgtattatat gtgctgtaac     3840

atcatgtacg ttacctccat ctattttagg atattttcct cacctatata ttatagggag     3900

aataatttag atacacatgc tcagagctga gatatttctc tgataaatca ggtaacaaaa     3960

tgtatttgat tgatggaatt ttgaagtaaa tgtgttttta tccatcagtt tctgagtaac     4020

aaagagcacc aagttttaat ttaaatagga gatttaacac tagggatcag ggagtttagt     4080

atgaagagtt aaaaaaattt aaaaaacagt gtaagctgtt gaaatggcaa gtgaattatt     4140

ttaatgatgt aataaaatat ttttaaattt tgacatagtg atcatttaat gaaaaaactc     4200

accaaaatgt ctccatttga attgtattga taatgtggga catatgtgtg attcaatata     4260

tacatatacc catatgtata tacagaaaat tatttttaat actttcctac tg             4312


<210>  2251
<211>  3741
<212>  DNA
<213>  homo sapiens

<400>  2251
ctgggtagac cggcgcgctc ccggggacgg tggggggggc agtcccggtt tcggccatcg       60

ctggggtggg ctcggagcgg ccgcaccggg cagcaacccc actcccactc ggaggccccc      120

tgccctctcc cccacttccc cccggcccat ggtgcgaggc tgggagccgc cgcccgggct      180

ggactgcgct atctctgaag ggcacaaatc agaaggcacc atgcctccta ataaagaggc      240

cagcggtctc agtagttcac cagcggggct catctgcctc cctccaatct ctgaggagct      300

acagcttgtg tggacgcaag cagcccagac cagtgagcta gacagcaatg aacacctgct      360

caaaaccttc agctactttc cctatcccag cctagcagac attgcccttc tctgcctacg      420

ttatgggttg cagatggaga aagtcaagac ttggtttatg gcccagcgcc tccgctgtgg      480

tattagctgg tcatctgaag aaatagaaga gactcgagcc cgagtagtct accgtcggga      540

ccaactccat ttcaaatccc ttctctcttt tactcatcat gcgggacggc ccccagagga      600

ggtgcctcct cctccagtgc cagctccaga gcaagttggt attggaatag gtcctccaac      660

tcttagcaag cctacccaga cgaaaggatt gaaggtagag cctgaggagc cctctcagat      720

gccaccactg ccacagagtc accagaaatt aaaggagtcc ctgatgacac ctggcagtgg      780

agcattcccc taccaatcag atttttggca acatcttcaa agcagtggcc tctcaaagga      840

gcaggcaggc aggggtccca accagtcaca tggcataggt actgcttcct ggaaccactc      900

cacaaccgtc ccccagccac aagctcggga taaaccccca ccaattgcat taattgccag      960

tagttgtaag gaggagtcag catctagtgt tactccctct tcttcctcta cctcttcttc     1020

tttccaggta ctggctaatg gagctactgc cgcctctaaa cccctccagc cactaggctg     1080

tgtcccacag tcagtgtcac ccagtgaaca ggcattaccc ccacatctgg aaccagcctg     1140

gccccaaggg ctacggcata actcagtacc aggtagagtt ggccccacag agtacctttc     1200

cccagatatg caacgccagc gaaagaccaa gcgcaaaacc aaagagcagc tggctatcct     1260

taaatccttt tttttacagt gccagtgggc acggcgtgag gattaccaaa agttagaaca     1320

gatcactggt ttacctcggc ctgagatcat tcagtggttt ggtgacacac gctatgcctt     1380

gaagcatggg caactaaagt ggtttcggga caacgcagta cctggtgccc ctagtttcca     1440

agacccagca attcctacac caccaccatc aacccgctcc ttgaacgaaa gggctgagac     1500

accacctctg ccgatccctc cacccccacc ggatatacaa cccttggaga ggtactgggc     1560

agcccaccaa cagctacggg aaactgatat ccctcaattg agtcaggcat caaggcttag     1620

cacccagcag gtgctggatt ggtttgactc tcgattacct cagccagctg aggtggtagt     1680

ttgtctagat gaagaagagg aagaggagga ggaagaactg ccagaagatg atgaggaaga     1740

ggaggaggag gaggaggaag atgatgatga tgatgatgat gatgtgatca tacaagactg     1800

agtggggagc tgggggaggg gaggtctgtt actgaaagat gaaccaactt agtaactgtt     1860

taaacaaaga aaccacattt ttaaaattac cttgtggcag agaactaaaa agctttgtgt     1920

tcttcagggt gggtggcagg gggatatagt gagggtggac cagggagaat gaccataggg     1980

cactaagtaa ggctgggatt ggatcagcag aaatccaacc ctctaacctt agggtaggga     2040

gtgctaagga tctggggaaa ccatgggctg ggaagctgct cttgctctcc tcgtgtctgc     2100

tgtttttttc ccttggtgta ctatacagag gccagatgtt ggcaccacct ctccaggagg     2160

attggaaagg aggagtaaag gattctgatt tgattgatga ttccagtgca tccccaatcc     2220

caccatctta cctggaatat aaggctgcct tgtacccctt ttctgagcac aagtctgtgc     2280

gtaatgcaac tgactctctt acttttttct tagtaactga tcatttccta gacaaccaag     2340

attctcaata agtcccagtc tcatcacaaa tattaatatt tccttttcct cataccaact     2400

tgactatgtt tcacccgctt catgactaaa tcacaggtgg cagaattttt cagttctttt     2460

tttttttttt gaggtggagt cttgctctgt cgcccaggct gtagtgcaat ggcgcaatct     2520

cagctcactg caagctccgc ctcccaggtt catgccattc tcctgcctca gcctcccgag     2580

tagctgggac tacaggcacc tgccaccaca cccggctact tttttatatt tttagtagag     2640

acgggtttca tcatgttagc caggatggtc ttgatctcct gacctcatga tccgcccacc     2700

ttggcctccc aaagtgctgg gattataggc atgagccacc gtgcccggct attttcagtt     2760

cttatgctgt gaccactttg ccttgtagct ttttctatct ttccaaaatc ctcactctgt     2820

tcattgtttg tctcagggaa aatcttcccc caccgagctt gtaaaaaact ttaataattg     2880

ggtggagaat aatttagaat ggatatttat tggaggtggt aattagggaa gatgtccttt     2940

taaacagtag aattgtgtta caaaggggtg aaagagaggg aatagtttct ccttgttgaa     3000

gggcagtgaa ggtaggtttc aggtttggtt ttacaaacct gttaactacc tcctgtccag     3060

cttgacagag actaattttt catctttttg ctgtcaattt gtttccagaa aagagacttt     3120

tccctctctt gataggatct gtcttaggga cagagggacc atcgtcttta agtgaattaa     3180

ttattgatgt tttagaatgg ttttcatcag ttgggatcag ctatatggca aataggtatc     3240

atcaatgagt taaccatcta aaaataaaag agtggaagcc ctaaaatgct agaataataa     3300

taaaaaggcc aaaaataaaa ttgtttctct ctcaaccact ttgccactcc tatggtttag     3360

ggattaatgg aaccaaatcc attaacattc taactcagca tacttttaac ttattgtttg     3420

gaggggcagg acttattgag gtaaattaaa agaacaaaaa ctgtaaaaag gaagtagttc     3480

agcatctatc gccagccagg ttgtttctca gccatcaaat gataatgact aaaatttctg     3540

aggcttcagg agtaacagag atacaacagt cttggaggta actccatttg ctacaggaca     3600

ggcccttgcc taaaagagaa ggtatctaga aatgccttta aaataaattc agagtaccag     3660

aaagggtatg gggatcctag ttcagataca agatcattcc caagacctaa tttatttctg     3720

gcagatgcct gctattttct g                                               3741


<210>  2252
<211>  3741
<212>  DNA
<213>  homo sapiens

<400>  2252
ctgggtagac cggcgcgctc ccggggacgg tggggggggc agtcccggtt tcggccatcg       60

ctggggtggg ctcggagcgg ccgcaccggg cagcaacccc actcccactc ggaggccccc      120

tgccctctcc cccacttccc cccggcccat ggtgcgaggc tgggagccgc cgcccgggct      180

ggactgcgct atctctgaag ggcacaaatc agaaggcacc atgcctccta ataaagaggc      240

cagcggtctc agtagttcac cagcggggct catctgcctc cctccaatct ctgaggagct      300

acagcttgtg tggacgcaag cagcccagac cagtgagcta gacagcaatg aacacctgct      360

caaaaccttc agctactttc cctatcccag cctagcagac attgcccttc tctgcctacg      420

ttatgggttg cagatggaga aagtcaagac ttggtttatg gcccagcgcc tccgctgtgg      480

tattagctgg tcatctgaag aaatagaaga gactcgagcc cgagtagtct accgtcggga      540

ccaactccat ttcaaatccc ttctctcttt tactcatcat gcgggacggc ccccagagga      600

ggtgcctcct cctccagtgc cagctccaga gcaagttggt attggaatag gtcctccaac      660

tcttagcaag cctacccaga cgaaaggatt gaaggtagag cctgaggagc cctctcagat      720

gccaccactg ccacagagtc accagaaatt aaaggagtcc ctgatgacac ctggcagtgg      780

agcattcccc taccaatcag atttttggca acatcttcaa agcagtggcc tctcaaagga      840

gcaggcaggc aggggtccca accagtcaca tggcataggt actgcttcct ggaaccactc      900

cacaaccgtc ccccagccac aagctcggga taaaccccca ccaattgcat taattgccag      960

tagttgtaag gaggagtcag catctagtgt tactccctct tcttcctcta cctcttcttc     1020

tttccaggta ctggctaatg gagctactgc cgcctctaaa cccctccagc cactaggctg     1080

tgtcccacag tcagtgtcac ccagtgaaca ggcattaccc ccacatctgg aaccagcctg     1140

gccccaaggg ctacggcata actcagtacc aggtagagtt ggccccacag agtacctttc     1200

cccagatatg caacgccagc gaaagaccaa gcgcaaaacc aaagagcagc tggctatcct     1260

taaatccttt tttttacagt gccagtgggc acggcgtgag gattaccaaa agttagaaca     1320

gatcactggt ttacctcggc ctgagatcat tcagtggttt ggtgacacac gctatgcctt     1380

gaagcatggg caactaaagt ggtttcggga caacgcagta cctggtgccc ctagtttcca     1440

agacccagca attcctacac caccaccatc aacccgctcc ttgaacgaaa gggctgagac     1500

accacctctg ccgatccctc cacccccacc ggatatacaa cccttggaga ggtactgggc     1560

agcccaccaa cagctacggg aaactgatat ccctcaattg agtcaggcat caaggcttag     1620

cacccagcag gtgctggatt ggtttgactc tcgattacct cagccagctg aggtggtagt     1680

ttgtctagat gaagaagagg aagaggagga ggaagaactg ccagaagatg atgaggaaga     1740

ggaggaggag gaggaggaag atgatgatga tgatgatgat gatgtgatca tacaagactg     1800

agtggggagc tgggggaggg gaggtctgtt actgaaagat gaaccaactt agtaactgtt     1860

taaacaaaga aaccacattt ttaaaattac cttgtggcag agaactaaaa agctttgtgt     1920

tcttcagggt gggtggcagg gggatatagt gagggtggac cagggagaat gaccataggg     1980

cactaagtaa ggctgggatt ggatcagcag aaatccaacc ctctaacctt agggtaggga     2040

gtgctaagga tctggggaaa ccatgggctg ggaagctgct cttgctctcc tcgtgtctgc     2100

tgtttttttc ccttggtgta ctatacagag gccagatgtt ggcaccacct ctccaggagg     2160

attggaaagg aggagtaaag gattctgatt tgattgatga ttccagtgca tccccaatcc     2220

caccatctta cctggaatat aaggctgcct tgtacccctt ttctgagcac aagtctgtgc     2280

gtaatgcaac tgactctctt acttttttct tagtaactga tcatttccta gacaaccaag     2340

attctcaata agtcccagtc tcatcacaaa tattaatatt tccttttcct cataccaact     2400

tgactatgtt tcacccgctt catgactaaa tcacaggtgg cagaattttt cagttctttt     2460

tttttttttt gaggtggagt cttgctctgt cgcccaggct gtagtgcaat ggcgcaatct     2520

cagctcactg caagctccgc ctcccaggtt catgccattc tcctgcctca gcctcccgag     2580

tagctgggac tacaggcacc tgccaccaca cccggctact tttttatatt tttagtagag     2640

acgggtttca tcatgttagc caggatggtc ttgatctcct gacctcatga tccgcccacc     2700

ttggcctccc aaagtgctgg gattataggc atgagccacc gtgcccggct attttcagtt     2760

cttatgctgt gaccactttg ccttgtagct ttttctatct ttccaaaatc ctcactctgt     2820

tcattgtttg tctcagggaa aatcttcccc caccgagctt gtaaaaaact ttaataattg     2880

ggtggagaat aatttagaat ggatatttat tggaggtggt aattagggaa gatgtccttt     2940

taaacagtag aattgtgtta caaaggggtg aaagagaggg aatagtttct ccttgttgaa     3000

gggcagtgaa ggtaggtttc aggtttggtt ttacaaacct gttaactacc tcctgtccag     3060

cttgacagag actaattttt catctttttg ctgtcaattt gtttccagaa aagagacttt     3120

tccctctctt gataggatct gtcttaggga cagagggacc atcgtcttta agtgaattaa     3180

ttattgatgt tttagaatgg ttttcatcag ttgggatcag ctatatggca aataggtatc     3240

atcaatgagt taaccatcta aaaataaaag agtggaagcc ctaaaatgct agaataataa     3300

taaaaaggcc aaaaataaaa ttgtttctct ctcaaccact ttgccactcc tatggtttag     3360

ggattaatgg aaccaaatcc attaacattc taactcagca tacttttaac ttattgtttg     3420

gaggggcagg acttattgag gtaaattaaa agaacaaaaa ctgtaaaaag gaagtagttc     3480

agcatctatc gccagccagg ttgtttctca gccatcaaat gataatgact aaaatttctg     3540

aggcttcagg agtaacagag atacaacagt cttggaggta actccatttg ctacaggaca     3600

ggcccttgcc taaaagagaa ggtatctaga aatgccttta aaataaattc agagtaccag     3660

aaagggtatg gggatcctag ttcagataca agatcattcc caagacctaa tttatttctg     3720

gcagatgcct gctattttct g                                               3741


<210>  2253
<211>  2798
<212>  DNA
<213>  homo sapiens

<400>  2253
gctgagcgcg gagccgcccg gtgattggtg ggggcggaag ggggccgggc gccagcgctg       60

ccttttctcc tgccgggtag tttcgctttc ctgcgcagag tctgcggagg ggctcggctg      120

caccgggggg atcgcgcctg gcagacccca gaccgagcag aggcgaccca gcgcgctcgg      180

gagaggctgc accgccgcgc ccccgcctag cccttccgga tcctgcgcgc agaaaagttt      240

catttgctgt atgccatcct cgagagctgt ctaggttaac gttcgcactc tgtgtatata      300

acctcgacag tcttggcacc taacgtgctg tgcgtagctg ctcctttggt tgaatcccca      360

ggcccttgtt ggggcacaag gtggcaggat gtctcagtgg tacgaacttc agcagcttga      420

ctcaaaattc ctggagcagg ttcaccagct ttatgatgac agttttccca tggaaatcag      480

acagtacctg gcacagtggt tagaaaagca agactgggag cacgctgcca atgatgtttc      540

atttgccacc atccgttttc atgacctcct gtcacagctg gatgatcaat atagtcgctt      600

ttctttggag aataacttct tgctacagca taacataagg aaaagcaagc gtaatcttca      660

ggataatttt caggaagacc caatccagat gtctatgatc atttacagct gtctgaagga      720

agaaaggaaa attctggaaa acgcccagag atttaatcag gctcagtcgg ggaatattca      780

gagcacagtg atgttagaca aacagaaaga gcttgacagt aaagtcagaa atgtgaagga      840

caaggttatg tgtatagagc atgaaatcaa gagcctggaa gatttacaag atgaatatga      900

cttcaaatgc aaaaccttgc agaacagaga acacgagacc aatggtgtgg caaagagtga      960

tcagaaacaa gaacagctgt tactcaagaa gatgtattta atgcttgaca ataagagaaa     1020

ggaagtagtt cacaaaataa tagagttgct gaatgtcact gaacttaccc agaatgccct     1080

gattaatgat gaactagtgg agtggaagcg gagacagcag agcgcctgta ttggggggcc     1140

gcccaatgct tgcttggatc agctgcagaa ctggttcact atagttgcgg agagtctgca     1200

gcaagttcgg cagcagctta aaaagttgga ggaattggaa cagaaataca cctacgaaca     1260

tgaccctatc acaaaaaaca aacaagtgtt atgggaccgc accttcagtc ttttccagca     1320

gctcattcag agctcgtttg tggtggaaag acagccctgc atgccaacgc accctcagag     1380

gccgctggtc ttgaagacag gggtccagtt cactgtgaag ttgagactgt tggtgaaatt     1440

gcaagagctg aattataatt tgaaagtcaa agtcttattt gataaagatg tgaatgagag     1500

aaatacagta aaaggattta ggaagttcaa cattttgggc acgcacacaa aagtgatgaa     1560

catggaggag tccaccaatg gcagtctggc ggctgaattt cggcacctgc aattgaaaga     1620

acagaaaaat gctggcacca gaacgaatga gggtcctctc atcgttactg aagagcttca     1680

ctcccttagt tttgaaaccc aattgtgcca gcctggtttg gtaattgacc tcgagacgac     1740

ctctctgccc gttgtggtga tctccaacgt cagccagctc ccgagcggtt gggcctccat     1800

cctttggtac aacatgctgg tggcggaacc caggaatctg tccttcttcc tgactccacc     1860

atgtgcacga tgggctcagc tttcagaagt gctgagttgg cagttttctt ctgtcaccaa     1920

aagaggtctc aatgtggacc agctgaacat gttgggagag aagcttcttg gtcctaacgc     1980

cagccccgat ggtctcattc cgtggacgag gttttgtaag gaaaatataa atgataaaaa     2040

ttttcccttc tggctttgga ttgaaagcat cctagaactc attaaaaaac acctgctccc     2100

tctctggaat gatgggtgca tcatgggctt catcagcaag gagcgagagc gtgccctgtt     2160

gaaggaccag cagccgggga ccttcctgct gcggttcagt gagagctccc gggaaggggc     2220

catcacattc acatgggtgg agcggtccca gaacggaggc gaacctgact tccatgcggt     2280

tgaaccctac acgaagaaag aactttctgc tgttactttc cctgacatca ttcgcaatta     2340

caaagtcatg gctgctgaga atattcctga gaatcccctg aagtatctgt atccaaatat     2400

tgacaaagac catgcctttg gaaagtatta ctccaggcca aaggaagcac cagagccaat     2460

ggaacttgat ggccctaaag gaactggata tatcaagact gagttgattt ctgtgtctga     2520

agtgtaagtg aacacagaag agtgacatgt ttacaaacct caagccagcc ttgctcctgg     2580

ctggggcctg ttgaagatgc ttgtatttta cttttccatt gtaattgcta tcgccatcac     2640

agctgaactt gttgagatcc ccgtgttact gcctatcagc attttactac tttaaaaaaa     2700

aaaaaaaagc caaaaaccaa atttgtattt aaggtatata aattttccca aaactgatac     2760

cctttgaaaa agtataaata aaatgagcaa aagttgat                             2798


<210>  2254
<211>  2723
<212>  DNA
<213>  homo sapiens

<400>  2254
cgggcgccgc aggagcgagt gagctgggag cgaggggcga aggcgcggag aagcccggcc       60

gcccggtggg cggcagaagg ctcagccgag gcggcggcgc cgactccgtt ccactctcgg      120

cccggatcca ggcctccggg ttcccaggcg ctcacctccc tctgacgcac tttaaagagt      180

ctcccccctt ccacctcagg gcgagtaata gcgaccaatc atcaagccat ttaccaggct      240

tcggaggaag ctgtttatgt gatccccgca ctaattaggc tcatgaacta acaaatcgtt      300

tgcacaactt gtgaagaagc gaacacttcc atggattgtc cttggactta gggcgccctg      360

cccgcctttt gcagaggaga aaaaactttt tttttttttt gcctcccccg agaactttcc      420

ccccttctcc tccctgcctc taactccgat ccccccacgc catctcgcca aaaaaaaaaa      480

aaaaaaaaaa aaagaaaaaa aaagaaaaaa aaagaaaaaa aattacccca atccacgcct      540

gcaaattctt ctggaaggat tttcccccct ctcttcaggt tgggcgcgtt tggtgcaaga      600

ttctcgggat cctcggcttt gcctctccct ctccctcccc cctcctttcc tttttccttt      660

cctttccttt ctttcttcct ttccttcccc ccacccccac ccccacccca aacaaacgag      720

tccccaattc tcgtccgtcc tcgccgcggg cagcgggcgg cggaggcagc gtgcggcggt      780

cgccaggagc tgggagccca gggcgcccgc tcctcggcgc agcatgttcc agccggcgcc      840

caagcgctgc ttcaccatcg agtcgctggt ggccaaggac agtcccctgc ccgcctcgcg      900

ctccgaggac cccatccgtc ccgcggcact cagctacgct aactccagcc ccataaatcc      960

gttcctcaac ggcttccact cggccgccgc cgccgccgcc ggtaggggcg tctactccaa     1020

cccggacttg gtgttcgccg aggcggtctc gcacccgccc aaccccgccg tgccagtgca     1080

cccggtgccg ccgccgcacg ccctggccgc ccacccccta ccctcctcgc actcgccaca     1140

ccccctattc gcctcgcagc agcgggatcc gtccaccttc tacccctggc tcatccaccg     1200

ctaccgatat ctgggtcatc gcttccaagg taaaagtatg gtttcagaac cgaagaacaa     1260

agttcaaaag gcagaagctg gaggaagaag gctcagattc gcaacaaaag aaaaaaggga     1320

cgcaccatat taaccggtgg agaatcgcca ccaagcaggc gagtccggag gaaatagacg     1380

tgacctcaga tgattaaaaa cataaaccta accccacaga aacggacaac atggagcaaa     1440

agagacaggg agaggtggag aaggaaaaaa ccctacaaaa caaaaacaaa ccgcatacac     1500

gttcaccgag aaagggagag ggaatcggag ggagcagcgg aatgcggcga agactctgga     1560

cagcgagggc acagggtccc aaaccgaggc cgcgccaaga tggcagagga tggaggctcc     1620

ttcatcaaca agcgaccctc gtctaaagag gcagctgagt gagagacaca gagagaagga     1680

gaaagaggga gggagagaga gaaagagaga gaaagagaga gagagagaga gagagagaaa     1740

gctgaacgtg cactctgaca aggggagctg tcaatcaaac accaaaccgg ggagacaaga     1800

tgattggcag gtattccgtt tatcacagtc cacttaaaaa atgatgatga tgataaaaac     1860

cacgacccaa ccaggcacag gacttttttg ttttttgcac ttcgctgtgt ttccccccca     1920

tctttaaaaa taattagtaa taaaaaacaa aaattccata tctagcccca tcccacacct     1980

gtttcaaatc cttgaaatgc atgtagcagt tgttgggcga atggtgttta aagaccgaaa     2040

atgaattgta attttctttt ccttttaaag acaggttctg tgtgcttttt attttgattt     2100

tttttcccaa gaaatgtgca gtctgtaaac actttttgat accttctgat gtcaaagtga     2160

ttgtgcaagc taaatgaagt aggctcagcg atagtggtcc tcttacagag aaacggggag     2220

caggacgacg ggggggctgg gggtggcggg ggagggtgcc cacaaaaaga atcaggactt     2280

gtactgggaa aaaaacccct aaattaatta tatttcttgg acattccctt tcctaacatc     2340

ctgaggctta aaaccctgat gcaaacttct cctttcagtg gttggagaaa ttggccgagt     2400

tcaaccattc actgcaatgc ctattccaaa ctttaaatct atctattgca aaacctgaag     2460

gactgtagtt agcggggatg atgttaagtg tggccaagcg cacggcggca agttttcaag     2520

cactgagttt ctattccaag atcatagact tactaaagag agtgacaaat gcttccttaa     2580

tgtcttctat accagaatgt aaatattttt gtgttttgtg ttaatttgtt agaattctaa     2640

cacactatat acttccaaga agtatgtcaa tgtcaatatt ttgtcaataa agatttatca     2700

atatgccctc aaaaaaaaaa aaa                                             2723


<210>  2255
<211>  3405
<212>  DNA
<213>  homo sapiens

<400>  2255
tctctcatcg tctgggcgag cggggcggct cgtggtgttt ctaacccagt tcgtggattc       60

aaaggtggct ccgcgccgag cgcggccggc gacttgtagg acctcagccc tggccgcggc      120

cgccgcgcac gccctcggaa gactcggcgg ggtgggggcg cgggggtctc cgtgtgcgcc      180

gcgggagggc cgaaggctga tttggaaggg cgtccccgga gaaccagtgt gggatttact      240

gtgaacagca tggaggagaa tgaccccaag cctggcgaag cagcggcggc ggtggaggga      300

cagcggcagc cggaatccag ccccggcggc ggctcgggcg gcggcggcgg tagcagcccg      360

ggcgaagcgg acaccgggcg ccggcgggct ctgatgctgc ccgcggtcct gcaggcgccc      420

ggcaaccacc agcacccgca ccgcatcacc aacttcttca tcgacaacat cctgcggccc      480

gagttcggcc ggcgaaagga cgcggggacc tgctgtgcgg gcgcgggagg aggaaggggc      540

ggcggagccg gcggcgaagg cggcgcgagc ggtgcggagg gaggcggcgg cgcgggcggc      600

tcggagcagc tcttgggctc gggctcccga gagccccggc agaacccgcc atgtgcgccc      660

ggcgcgggcg ggccgctccc agccgccggc agcgactctc cgggtgacgg ggaaggcggc      720

tccaagacgc tctcgctgca cggtggcgcc aagaaaggcg gcgaccccgg cggccccctg      780

gacgggtcgc tcaaggcccg cggcttgggc ggcggcgacc tgtcggtgag ctcggactcg      840

gacagctcgc aagccggcgc caacctgggc gcgcagccca tgctctggcc ggcgtgggtc      900

tactgtacgc gctactcgga ccggccttct tcaggtccca ggtctcgaaa accaaagaag      960

aagaacccga acaaagagga caagcggccg cgcacggcct ttaccgccga gcagctgcag     1020

aggctcaagg ccgagttcca gaccaacagg tacctgacgg agcagcggcg ccagagcctg     1080

gcgcaggagc tgagcctcaa cgagtcacag atcaagattt ggttccagaa caagcgcgcc     1140

aagatcaaga aggccacggg caacaagaac acgctggccg tgcacctcat ggcacagggc     1200

ttgtacaacc actccaccac agccaaggag ggcaagtcgg acagcgagta gggcgggggg     1260

catggaggcc aggtctcagt ccgcgctaaa caatgcaata atttaaaatc ataaagggcc     1320

agtgtataaa gattatacca gcattaatag tgaaaatatt gtgtattagc taaggttctg     1380

aaatattcta tgtatatatc atttacaggt ggtataaaat ccaaaatatc tgactataaa     1440

atattttttt gagttttttg tgtttatgag attatgctaa ttttatgggt ttttttcttt     1500

tttgcgaagg gggctgctta gggtttcacc tttttttaat cccctaagct ccattatatg     1560

acattggaca cttttttatt attccaaaag aagaaaaaat taaaacaact tgctgaagtc     1620

caaagatttt ttattgctgc atttcacaca actgtgaacc gaataaatag ctcctatttg     1680

gtctatgact tctgccactt tgtttgtgtt ggcttggtga ggacagcagg aggggcccac     1740

acctcaagcc tggaccagcc acctcaaggc cttggggagc ttaggggacc tggtgggaga     1800

gaggggactt ccagggtcct tgggccagtt ctgggatttg gccctgggaa gcagcccagc     1860

gtaccccagg cctgctctgg gaagtcggct ccatgctcac cagcagccgc ccaggcccgc     1920

agcctcaccc ggctccctct cctcaccctc ctgcacctaa ctccctcctc cttctccttt     1980

ttcctcctct tcctccttcc tccttcctcc tgctcctcct ttcttcttct ttttcttctc     2040

ctcctcctcc ttccttcctc ctcctccttc tctttcctcc tcctcctcac caagggccca     2100

accgtgtgca tacatcgtct gcgtctgtgg tctgtgtcgc tgtccccagt cccaccgcag     2160

tcctgccgca ggcctaaccc tcctgccctg ggcactgcct ccatgcagaa gcgcttcgag     2220

gttctggggc taaaggcctg gggtgtgtgg cctaaagccc aagagcggtg gggcgaccct     2280

ccttttggct tggccccagg aatttcctgt gactccacca gccatcatgg gtgccagcca     2340

gggtcccaga aatgaggcca tggctcactg tttctgggcg ggcagaaggc tctgtagagg     2400

gagatggcat catctatctt cctttccttt ttcttttctt ccctattttt ttcttttttt     2460

cctttatttt tttcttttct tggagtggct gcttctgcta tagagaacat tcttccaaga     2520

taaatatgtg tgtttacaca tatgtctgca tgcatgtgaa cacacacaca cacacacaca     2580

caccaggcgt gtttgagtcc acagttctga aacatgtggc taccttgtct ttcaaaagaa     2640

ctcagaatcc tccaggatct agaagaagga agaaagtgtg taaataatca tttcttatca     2700

tcactttttg tcttttcttg ttttttaaaa tatacatttt atttttgaag gtgtggtaca     2760

gtgtaaatta aatatattca atatatttcc caccaagtac ctatatatgt atataaacaa     2820

acacattatc tatatataac gccacactgt cttctgttta gtgtatgggg aaagaccaat     2880

ccaactgtcc atctgtggct gggacagccc agggggtgtg cccacggctg acccaggggt     2940

gtgcacacgg ctgagctggg agtcccgctg gtctccctga ggactgaggg tgaacttcgc     3000

tctttgcctt aaacctcttt atttcattgc agtaatagtt ttacgttgta cataatagtg     3060

taaacctttt taaaaaggaa agtataaaaa caaaagttgt aatttaaaag tctgaataac     3120

catctgctgc ttaggaaact caatgaaatg acatgccttt ttagcaggaa gcaaagttgg     3180

tttctgtttt ttgttttctt tgttgtttta gtttataaaa catgtgcatt ttacagttcc     3240

agtatcaaat atttataatc ttatgagaaa tgaatgaatg tttctattta caactgtgct     3300

tatcaaaatt gtgaacaccc ccacccccgc atttttgtgt gttgaaattc ttgaaggtta     3360

cattaaataa aacaaaatct ctttattata aaataaaaaa aaaaa                     3405


<210>  2256
<211>  2310
<212>  DNA
<213>  homo sapiens

<400>  2256
gtaatttgcc tggcaagtga tcagactggt ataaaataac atcatctgtt aggcaagata       60

gcagtcacaa agaactattg gtcttttaaa atatagaatt tttaatgaga aactttgaat      120

aatagagatt gaacatgtga gaacagctac ctagtgtgtg ttgcattatt aacccctagt      180

ttgtagtgta ttctggagtc aagttgacct acatagaaga gaaggaactg gaagtgcatg      240

tctgtgttct ggctccgatt gggaaaagct gcttaaccac tgttacactt ccaggggctc      300

cccactcagt ccccagtcat ctatcgacag tgagctgagt acttcagaat tggaggatga      360

ttctatctcc atgggatata aattacagga cctcactgat gttcagatca tggctcgtct      420

gcaagaagaa agtctcaggc aagattatgc ttctacttca gcatctgtat caagacatag      480

ttccagtgtg tcattgagtt caggaaaaaa agggacatgt agtgatcaag aatatgacca      540

atacagtctg gaggatgaag aggaatttga tcatttgcca ccacctcagc ctcgtcttcc      600

aagatgttcc cctttccaaa gaggaattcc ccattcacag actttctcca gcattcggga      660

gtgtaggagg agccccagtt cccagtattt tccttcaaat aattaccagc agcaacagta      720

ttattcacct caagcccaaa ctccagatca gcaaccaaat aggaccaatg gagataagct      780

ccgaagaagt atgcctaacc tagcccggat gccaagtaca actgccatta gtagcaacat      840

tagttctccg gtcaccgtgc gaaatagtca gagttttgac tcaagcttgc atggagctgg      900

aaatggaatt tcaagaatac aatcttgtat tccatcaccg ggacagcttc aacacagggt      960

ccacagcgtg gggcatttcc cagtgtctat ccgacagcct cttaaagcca cagcctatgt     1020

gagtccaacc gttcaaggca gcagtaacat gcctttatca aacggcttac agctgtattc     1080

caacacagga atccccacac cgaacaaagc tgcagcttct gggataatgg gtcgcagtgc     1140

actcccaaga ccttcgttgg caataaatgg gagtaacctg cctcgaagca aaattgcaca     1200

acctgttaga agttttcttc agcctccaaa gcctctgtct tcactcagca ctctgaggga     1260

tggaaattgg agagatggtt gctactaatg cagttttatg tacccttgaa aaatgggaaa     1320

gaagtaaaaa tgagggttgt gttacctagc tggctgggta gcagtggatg ttgggatatt     1380

ctttcccttt tgtgttttaa tatatttact gcattgtttc tcaatggacc agtcaccaga     1440

gactaattat tgcacttaaa tatttgcctg agatactgca acattctcaa acccatggtt     1500

gcagtattgt gacacttaga tctaggaagt ttttgtagaa ctgctctgta cctgaatact     1560

ttttgagaga attaagatgt atcaataatg ctttgccata tgagtttttt aaagtaactt     1620

gttcaattta ctcacgtgtt ctaaacatct ttccattaca tgttctgtat tttaatacat     1680

tgcatattga caactaggtt ctataatgta tgctttgaaa tttacttttt tatagtttac     1740

aggaatttta ttttttgtgc ctatttcttt ttacacctat gtgaaccact atggaacaac     1800

ttaaattttg tgccataaaa atatttttgt ggtaaggtac tattttttta gctctaggga     1860

tatatcagca aaaacacatc atgcaatttg agacacataa ttttgtgttg aatgagcaca     1920

acataatttg aagcattgca aggagataac cagacagcag aattaaatgg tcctgtcttt     1980

ttcattttta atttattgtc atacatgggt ttcatattta taacggcatc atgagctcat     2040

tgcacttaat acctgcaatg tttgctactg taccacaatt gattttcaat actttattac     2100

gaaggatgaa actgtaatgt tttattaaca atgcttctgg aaatgaatgc attttaaagc     2160

aaataaatct ttttgataga ccttttacaa aatccatttg cactaatgaa tgctttctta     2220

tggcatataa cttaatattt gttactgtgt acactgctgt tttggaatgt tcagaaataa     2280

agactctatt tcagcaatat caggtcatgc                                      2310


<210>  2257
<211>  2118
<212>  DNA
<213>  homo sapiens

<400>  2257
acccgggggg ccgcgctgcg cggagtgcca ggctgcgggc ggctgcagac ctgggagcgg       60

agaccggccc gccgcccccg acgccgccga gcacgtcagc ggcgcgcagc cggggctcgg      120

agaccgacgg gcagaacgac gggcggcgac tgcggcgacc gcgggacggc gagaggcacg      180

cggcgggagg ggaccggaat ccgcagctcc ggccgcgcca tggacggcaa cgacaacgtg      240

accctgctct tcgcccctct gctgcgggac aactacaccc tggcgcccaa tgccagcagc      300

ctgggccccg gcacggacct cgccctcgcc cctgcctcca gcgccggccc cggccctggg      360

ctcagcctcg ggccgggtcc gagcttcggc ttcagccccg gccccactcc gaccccggag      420

cccacgacca gcggcctcgc gggcggcgcg gcgagccacg gcccttcccc gttccctcgg      480

ccctgggcgc cccacgcgct cccgttctgg gacacgccgc tgaaccacgg gctgaacgtg      540

ttcgtgggcg ccgccctgtg catcaccatg ctgggcctgg gctgcacggt ggacgtgaac      600

cacttcgggg cgcacgtccg tcggcccgtg ggcgcgctgc tggcagcgct ctgccagttc      660

ggcctcctgc cgctgctggc cttcctgctg gccctcgcct tcaagctgga cgaggtggcc      720

gccgtggcgg tgctcctgtg tggctgctgt cccggcggca atctctccaa tcttatgtcc      780

ctgctggttg acggcgacat gaacctcagc atcatcatga ccatctcctc cacgcttctg      840

gccctcgtct tgatgcccct gtgcctgtgg atctacagct gggcttggat caacacccct      900

atcgtgcagt tactacccct agggaccgtg accctgactc tctgcagcac tctcatacct      960

atcgggttgg gcgtcttcat tcgctacaaa tacagccggg tggctgacta cattgtgaag     1020

gtttccctgt ggtctctgct agtgactctg gtggtccttt tcataatgac cggcactatg     1080

ttaggacctg aactgctggc aagtatccct gcagctgttt atgtgatagc aatttttatg     1140

cctttggcag gctacgcttc aggttatggt ttagctactc tcttccatct tccacccaac     1200

tgcaagagga ctgtatgtct ggaaacaggt agtcagaatg tgcagctctg tacagccatt     1260

ctaaaactgg cctttccacc gcaattcata ggaagcatgt acatgtttcc tttgctgtat     1320

gcacttttcc agtctgcaga agcggggatt tttgttttaa tctataaaat gtatggaagt     1380

gaaatgttgc acaagcgaga tcctctagat gaagatgaag atacagatat ttcttataaa     1440

aaactaaaag aagaggaaat ggcagacact tcctatggca cagtgaaagc agaaaatata     1500

ataatgatgg aaaccgctca gacttctctc taaatgtgga gatacacagg agcttctatc     1560

ttgctgaaat attgcttcat atttatagcc tgtggtagtg cacatggtta acataaaaga     1620

taacactggt tcacatcata catgtaacaa ttctgatctt tttaaggttc actggtgtat     1680

taaccaaacg ttgtcacaaa ttacaaatca atgctgtaat ataatttgca cctggaatgg     1740

ctaacgtgaa gcctgaatta aatgtggttt ttagttttta ccatcaccaa tttctatgac     1800

tgttgcaaat acagaatcta ttagaaaaca gggtcttgga aatgtagaat tttggcgcac     1860

tatgaggaaa aacaagctat ctttgtaaag cataattgag tttaatgtaa ttgttgtaaa     1920

aaaaaaagtg tgcttgctct acttaaaatt cctcacaatg ttgaattttg acctgtattc     1980

agaagaattc caaaacaggt cagttaaata aggaaatata gtatttgtca aaccagtatc     2040

agagaaaagt tacattaatg tatttgatta cttgatctgg tatctactta ttaatgaata     2100

atcaacattt ttctagtg                                                   2118


<210>  2258
<211>  2172
<212>  DNA
<213>  homo sapiens

<400>  2258
cttgaaagta accgcacctt ccaaagggca ccgtgcaatc agactgaaac cacagtgcaa       60

atttaattgc cggggaagat aacgggcctt ggtgccctcc aagcgtcagc tgagtttcca      120

agaagccggg cagcgggcgc ccgcgggttc gtctctggct cctcctccgc cacagcagcc      180

gggggcccgg gtcggaggcg gcgggggccg agcgcccggc ctcgcaagcc cacggcccgc      240

tgggggtgcc gtcccgcgcc ggggcggagc aggccccggc agcccagttc ctcattctat      300

cagcggtaca aggggctggt ggcgccacag gcgctgggac cgcgggcgga caaggatggg      360

tccgcgcggc gcggcgagct tgccccgagg ccccggacct cggcggctgc tcctccccgt      420

cgtcctcccg ctgctgctgc tgctgttgtt ggcgccgccg ggctcgggcg ccggggccag      480

ccggccgccc cacctggtct tcttgctggc agacgaccta ggctggaacg acgtcggctt      540

ccacggctcc cgcatccgca cgccgcacct ggacgcgctg gcggccggcg gggtgctcct      600

ggacaactac tacacgcagc cgctgtgcac gccgtcgcgg agccagctgc tcactggccg      660

ctaccagatc cgtacaggtt tacagcacca aataatctgg ccctgtcagc ccagctgtgt      720

tcctctggat gaaaaactcc tgccccagct cctaaaagaa gcaggttata ctacccatat      780

ggtcggaaaa tggcacctgg gaatgtaccg gaaagaatgc cttccaaccc gccgaggatt      840

tgatacctac tttggatatc tcctgggtag tgaagattat tattcccatg aacgctgtac      900

attaattgac gctctgaatg tcacacgatg tgctcttgat tttcgagatg gcgaagaagt      960

tgcaacagga tataaaaata tgtattcaac aaacatattc accaaaaggg ctatagccct     1020

cataactaac catccaccag agaagcctct gtttctctac cttgctctcc agtctgtgca     1080

tgagcccctt caggtccctg aggaatactt gaagccatat gactttatcc aagacaagaa     1140

caggcatcac tatgcaggaa tggtgtccct tatggatgaa gcagtaggaa atgtcactgc     1200

agctttaaaa agcagtgggc tctggaacaa cacggtgttc atcttttcta cagataacgg     1260

agggcagact ttggcagggg gtaataactg gccccttcga ggaagaaaat ggagcctgtg     1320

ggaaggaggc gtccgagggg tgggctttgt ggcaagcccc ttgctgaagc agaagggcgt     1380

gaagaaccgg gagctcatcc acatctctga ctggctgcca acactcgtga agctggccag     1440

gggacacacc aatggcacaa agcctctgga tggcttcgac gtgtggaaaa ccatcagtga     1500

aggaagccca tcccccagaa ttgagctgct gcataatatt gacccgaact tcgtggactc     1560

ttcaccgtac tggcctgagt gctcgctgct gttgtagcta ccaccaactt tctactgaag     1620

atgataaccc agggcataag aaatgacttc agacccaagg ttctgaaagg gcccctcaag     1680

gcctcgggtg gctcctgcag aagtggcaga agaggcggga actaggaacc tggcatcata     1740

ggaaaagtgc cttctccaag aaagaagggg ccccaggagg ctgtcttact tagatcaacc     1800

ataaactacc acagatgggt catttcttat attatttcaa aatatctttg aagatgagaa     1860

ttcatttgtg tccttcatag accaaagttc tttgtgttac cttttcccaa aagtaaattc     1920

ctttcccttt attcattcct tgtggaaata aaatgcaagc cctttatact tgtcttacag     1980

taatatggca catgtagctt acttttgagc atcccagtga ataatgtttg gaacttttct     2040

tattacctaa tagcatatag agaagagtga agtcagctaa aaacagaaat tttgaaaagc     2100

catcttcagg aaaatgtagg cccagatgct ttcctccacc ttttttgaca ggctgccaca     2160

tacagtttca ca                                                         2172


<210>  2259
<211>  2885
<212>  DNA
<213>  homo sapiens

<400>  2259
ttgtcctgag cgcggagagg gcgagctcgg gccgcgggca gggcgggagc cggcagccgg       60

caaccaaggg aggcagaaag gcacaaagat cgcaataata tccgttataa cccgctatct      120

aaccccaccc ccaacacaca cccatccatc ccaccctccg ggagaggcag ccggcgatcc      180

gctctctgcg ccctgggaaa aagccccagc catgagcaat cagtaccagg aggagggctg      240

ctccgagagg cccgagtgca aaagtaaatc tccaactttg ctctcctcct actgcatcga      300

cagcatcctg ggccggagga gcccgtgcaa aatgcggttg ctgggagccg cgcagagctt      360

gcctgctccg ctgaccagcc gcgccgaccc ggaaaaggcc gtgcaaggct cccctaagag      420

cagcagcgcc ccgttcgagg ccgagctgca cctgccgccc aagctgcggc gcctgtacgg      480

cccgggcggg ggccgcctcc ttcagggtgc ggcagcggcg gcggcggcgg cggcggcggc      540

ggcggcagcg gccgccacgg ccacggcggg tccacgcggg gaggcccctc cgccgccacc      600

gccaaccgcg cggcccgggg aacggccgga cggcgcaggg gccgccgcgg cagccgcggc      660

cgcggccgcc gcggcctggg acacgctcaa gatcagccag gcgccgcagg tgagcatcag      720

ccgcagcaag tcgtaccgcg agaacggggc gcccttcgtg ccgccgccgc ccgcgctgga      780

cgagctgggc ggcccggggg gcgtcacgca cccggaggag cgcctcggcg tggccggcgg      840

cccgggcagc gccccggctg cgggtggtgg caccggcacc gaggacgacg aggaggagct      900

gctggaggac gaagaagatg aggacgagga agaggaactg ctggaggacg acgaggagga      960

gctgctggag gacgacgccc gcgcgctgct caaggagccc cggcgctgtc ctgtggccgc     1020

cactggcgcc gtggccgcag cagctgccgc tgcagtggcc acagagggcg gggagctgtc     1080

acccaaggag gagctgctgc tgcacccgga agacgctgag ggcaaggacg gcgaggacag     1140

cgtgtgcctc tctgcgggca gcgactcgga ggaggggctg ctgaaacgca aacagaggcg     1200

ctaccgcacc acgttcacca gctaccagct ggaggaactg gagcgggcct tccagaagac     1260

gcactacccg gacgtcttca ccagggagga actggccatg aggctggact tgaccgaggc     1320

ccgagtccag gtctggttcc agaaccgtcg ggccaagtgg cgcaagcggg agaaggcagg     1380

cgcgcagacc cacccccctg ggctgccctt cccggggccg ctctccgcca cccacccgct     1440

cagcccctac ctggacgcca gccccttccc tccgcaccac ccggcgctcg actccgcttg     1500

gactgccgct gccgccgccg ccgccgccgc cttcccgagc ctacctccgc ctccgggctc     1560

ggccagcctg ccgcccagcg gggcgccgct gggcctgagc actttcctcg gagcggcagt     1620

gttccgacac ccagctttca tcagcccggc attcggcagg ctcttttcca caatggcccc     1680

cctgaccagc gcgtcgaccg cggccgcgct cctgagacag cccacacccg ccgtggaggg     1740

cgcagtggca tcgggcgccc tggccgaccc ggccacggcg gccgcagaca gacgcgcctc     1800

tagcatagcc gcgctgaggc tcaaggccaa ggagcacgcg gcgcagctca cgcagctcaa     1860

catcctgccg ggcaccagca cgggcaagga ggtgtgctaa aggctgccct ccacacccgc     1920

gccccgcgcg cgccccgaaa ggtcacctca ctcagcacca ctcaagacca aatggaaaca     1980

gaggaccagc acactcccga gacggcactg agagagcgca gccgccttca cagcagtctg     2040

gatgcgggca tggcagccct cggcgctccg ggacgtggca cctcctcggc tggctgtcca     2100

cccgcccctg cccctgcccc tgctactgcc aacctcgctc caactccaac atccactctc     2160

tcttgttctt actttcctga aaatatcggg gaggttttct cccccagacg cctgatattg     2220

aagtaaaaaa tttaaaaagc ccaacctctt cctcctgaca ccccacttag cctttctttt     2280

ctttctttct ttctttcttt ttttttttta aatagcattt tggcgctcga agttgatctc     2340

cccagcgagg gccccagcgt gaagccaggg cccgggaagc aaatgcgagc ctgtaagata     2400

gctaacagtg cacttaaagg aaaggggcgt cttgttcttg ttctcttctt tatcatacac     2460

caaccaaggt ttttatatca aaccaaaggg aaataatact ctgctagaat atggactgtt     2520

gaagtcacca aactgtgatt attgattctg tacataccat tgttattaaa aaaaaaaaaa     2580

aaagaacaga gctttgtata tttgaaatgt tataacgcaa ttgcactcag cgtggtatgg     2640

taaaagtttg tcctcccgta gattcttact gtgttgtaga tacggtaggg ttcctagaca     2700

aatatttatg tactcaagcc ctttatttaa cttattaact gtagaggctt ccgaaacctt     2760

caagataaag gcaatggtac agtacttttg tgtaatgtgt aattgttacc acttttcctt     2820

gctatctagt ggagaagtgt cacgctcaaa ataaaaaaat tatatgttta acaaaaaaaa     2880

aaaaa                                                                 2885


<210>  2260
<211>  2525
<212>  DNA
<213>  homo sapiens

<400>  2260
aaagtttccg agtccattcc gggagcggga gcccatcttg ctggctgccg aggccctcgc       60

tggaggagga gggtcagaac tcgggtgcag ccaatcgagg gcaacgctgc tacttatcag      120

agcagaatgg gctgtagttt agtgaaatag gaaagctgca aaacactgtg gagtgctccc      180

gtgtaaataa aaagaggaaa aaagtttctc aagtcgccgc tgcacgacgt ctggccggcg      240

ctggagcggg ggtctgcgct ctcccgagcg gccgcgcgct ggactttatt gtgccgcaac      300

cagccccagt tcccattgtt tgtgtttttt tcaaaatatg gcaaaggttc aggtgaacaa      360

tgtagtggtg ctggataacc cttctccttt ctacaacccg ttccagttcg agatcacctt      420

cgagtgcatc gaggacctgt ctgaagactt ggaatggaaa attatctatg tgggctctgc      480

agaaagtgaa gaatacgatc aagttttaga ctctgtttta gtgggtcctg ttcccgcagg      540

aaggcatatg tttgtatttc aggctgatgc acctaatcca ggactcattc cagatgcaga      600

tgcagtaggc gtaactgttg tgctaattac ttgtacctat cgaggacaag aatttattag      660

agttggctat tatgtaaata atgaatatac tgagacagaa ttaagggaaa atccaccagt      720

aaaaccagac ttttctaagc ttcaaaggaa tattttggca tctaatccca gggtcacaag      780

attccacatt aattgggaag ataacacaga aaaactggaa gatgcagaga gcagtaatcc      840

aaatctacag tcacttcttt caacagatgc attaccttca gcatcaaagg gatggtccac      900

atcagaaaac tcactaaatg tcatgttaga atcccacatg gactgcatgt gaccacctac      960

catcccttta gtacaaatta agctattaaa aatacacaga actatttccc tgaaattccg     1020

taagtacata gtcaaaacac aatgtgaaga atttgtttaa aaacatcctg tagaaagttt     1080

ataagaaaac cagtatttga acaaattgtg gaatataaat acaactattt ttaagtaatt     1140

tttttctcta atgtgttatt ttatttgttc tgaaactaat ctgattaaag catatatatt     1200

attttcttct cctttatatg taatgaaagc acttataaag aaacaggaat cattagacca     1260

ggttgtaaag atgtcttggc ctcccagaca gtctttggac cactatttta ctggcctttg     1320

aaagaacaaa gtttacttca actaaaatgt ttcttcctgt gaagacatat ggtatcattt     1380

taatttaagg ggcagatttc cattcttttt tggcatgtcc ttaaaaagag gatttgaaat     1440

caactatatg ctaccaagaa ctttaggatc caattttcca agccaccgtg aagcctctta     1500

tggctactat tatagttcat gagatgttgg acagcatttg gtttgtttgg taagagaaga     1560

acaaatatgg ctaattgtta ataaggtccc ctggctatgg tttttgttct tataacagag     1620

tttagaatat cagagcattt cttgaatcat acatcattat tgtccagtga attcaagacc     1680

aaatacaata tcgggagaaa atacaaactc cctgtgttta agaatagggg attacaatgg     1740

ctcaaattgg ttcatttgat ttctaaaaat accatgacct ttaaaaattc ttttaataga     1800

tcatgttatt ggcagtattt atataaaaac catggattta gaaaggtata tttagcttta     1860

ttataataga tacgttacta ttttggaaat atatatattt tcacacctgt agtactcttc     1920

cccatttcct ctgacactca tgcagaatga gatcaggcat atttgtggtt gacatactct     1980

agatagcttt tccaacaaat ctttgaaaag caatcttgga aaggaattca ttaactaaat     2040

ggggtaaaag gtttcttttt ctttgagagt taagtccttc ctcaaaaaat tttcttatgc     2100

tccataaaat tgaggtagaa tattttcatt attcttgcag ctaagcaaga cagccatatg     2160

atgcaggtta tgcagtgcct tcatatctaa aacttttata ctgcactttt taaagctttt     2220

atgttgagga aaggaaaagg gcatttgtct aaacatggat tctgagttgt atatatttcc     2280

tatcattcta aaaaagtgaa tttgtgaagc aaagttttgc cagatgttaa actttgaatt     2340

taatatacca gattattaaa atattgtcca ttaactagtt catagatttt aaaagtaaaa     2400

tacttctgac tgttaaaact atataaagaa aatctcattt gtctaattgc aattaaaaga     2460

aaaatgttaa aatattaaaa tgaaaataaa agcattactt tccaacaaaa aaaaaaaaaa     2520

aaaaa                                                                 2525


<210>  2261
<211>  2270
<212>  DNA
<213>  homo sapiens

<400>  2261
aatggggcgc cgactcggcg caggaacaag gcgggggttc ggggccggct gcagactctc       60

accgcagcgg ccaggaacgc cagccgttca cgcgttcggt cctccttggc tgactcaccg      120

ccctggccgc cgcaccatgg acgcccccag gcaggtggtc aactttgggc ctggtcccgc      180

caagctgccg cactcagtgt tgttagagat acaaaaggaa ttattagact acaaaggagt      240

tggcattagt gttcttgaaa tgagtcacag gtcatcagat tttgccaaga ttattaacaa      300

tacagagaat cttgtgcggg aattgctagc tgttccagac aactataagg tgatttttct      360

gcaaggaggt gggtgcggcc agttcagtgc tgtcccctta aacctcattg gcttgaaagc      420

aggaaggtgt gctgactatg tggtgacagg agcttggtca gctaaggccg cagaagaagc      480

caagaagttt gggactataa atatcgttca ccctaaactt gggagttata caaaaattcc      540

agatccaagc acctggaacc tcaacccaga tgcctcctac gtgtattatt gcgcaaatga      600

gacggtgcat ggtgtggagt ttgactttat acccgatgtc aagggagcag tactggtttg      660

tgacatgtcc tcaaacttcc tgtccaagcc agtggatgtt tccaagtttg gtgtgatttt      720

tgctggtgcc cagaagaatg ttggctctgc tggggtcacc gtggtgattg tccgtgatga      780

cctgctgggg tttgccctcc gagagtgccc ctcggtcctg gaatacaagg tgcaggctgg      840

aaacagctcc ttgtacaaca cgcctccatg tttcagcatc tacgtcatgg gcttggttct      900

ggagtggatt aaaaacaatg gaggtgccgc ggccatggag aagcttagct ccatcaaatc      960

tcaaacaatt tatgagatta ttgataattc tcaaggattc tacgtttgtc cagtggagcc     1020

ccaaaataga agcaagatga atattccatt ccgcattggc aatgccaaag gagatgatgc     1080

tttagaaaaa agatttcttg ataaagctct tgaactcaat atgttgtcct tgaaagggca     1140

taggtctgtg ggaggcatcc gggcctctct gtataatgct gtcacaattg aagacgttca     1200

gaagctggcc gccttcatga aaaaattttt ggagatgcat cagctatgaa cacatcctaa     1260

ccaggatata ctctgttctt gaacaacata caaagtttaa agtaacttgg ggatggctac     1320

aaaaagttaa cacagtattt ttctcaaatg aacatgttta ttgcagattc ttcttttttg     1380

aaagaacaac agcaaaacat ccacaactct gtaaagctgg tgggacctaa tgtcacctta     1440

attctgactt gaactggaag cattttaaga aatcttgttg cttttctaac aaattcccgc     1500

gtattttgcc tttgctgcta ctttttctag ttagatttca aacttgcctg tggacttaat     1560

aatgcaagtt gcgattaatt atttctggag tcatgggaac acacagcaca gagggtaggg     1620

gggccctcta ggtgctgaat ctacacatct gtggggtctc ctgggttcag cggctgttga     1680

ttcaaggtca acattgacca ttggaggagt ggtttaagag tgccaggcga agggcaaact     1740

gtagatcgat ctttatgctg ttattacagg agaagtgaca tactttatat atgtttatat     1800

tagcaaggtc tgtttttaat accatatact ttatatttct atacatttat atttctaata     1860

atacagttat cactgatata tgtagacact tttagaattt attaaatcct tgaccttgtg     1920

cattatagca ttccattagc aagagttgta ccccctcccc agtcttcgcc ttcctctttt     1980

taagctgttt tatgaaaaag acctagaagt tcttgattca tttttaccat tctttccata     2040

ggtagaagag aaagttgatt ggttggttgt ttttcaatta tgccattaaa ctaaacattt     2100

ctgttaaatt accctatcct ttgttctcta ctgttttctt tgtaatgtat gactacgaga     2160

gtgatacttt gctgaaaagt ctttccccta ttgtttatct attgtcagta ttttatgttg     2220

aatatgtaaa gaacattaaa gtcctaaaac atctaaaaaa aaaaaaaaaa                2270


<210>  2262
<211>  4423
<212>  DNA
<213>  homo sapiens

<400>  2262
gcgtgggctc ccgatgggct gcctgagcgg gtgcgcgggc aacttccggt gtgggtgacg       60

agtggtggcc gaagcagggg gacagcaagg gacgctcagg cggggaccat ggcggacggc      120

ggctcggagc gggctgacgg gcgcatcgtc aagatggagg tggactacag cgccacggtg      180

gatcagcgcc tacccgagtg tgcgaagcta gccaaggaag gaagacttca agaagtcatt      240

gaaacccttc tctctctgga aaagcagact cgtactgctt ccgatatggt atcgacatcc      300

cgtatcttag ttgcagtagt gaagatgtgc tatgaggcta aagaatggga tttacttaat      360

gaaaatatta tgcttttgtc caaaaggcgg agtcagttaa aacaagctgt tgccaaaatg      420

gttcaacagt gctgtactta tgttgaggaa atcacagacc ttcctatcaa acttcgatta      480

attgatactc tacgaatggt taccgaaggc aagatttatg ttgaaattga gcgtgcgcga      540

ctgactaaaa cattagcaac tataaaagaa caaaatggtg atgtgaaaga ggcagcctcc      600

attttacagg agttacaggt ggaaacctac gggtcaatgg aaaagaaaga gcgagtggaa      660

tttattttgg agcaaatgag gctctgccta gctgtgaagg attacattcg aacacaaatc      720

atcagcaaga aaattaacac caaatttttc caggaagaaa atacagagaa attaaagttg      780

aagtactata atttaatgat tcagctggat caacatgagg gatcctattt gtctatttgt      840

aagcactaca gagcaatata tgatactccc tgtatacagg cagaaagtga aaaatggcag      900

caggctctga agagtgttgt actctatgtt atcctggctc cttttgacaa tgaacagtca      960

gatttggttc accgaataag tggtgacaag aagttagaag aaattcccaa atacaaggat     1020

cttttaaagc tttttaccac aatggagttg atgcgttggt ccacacttgt tgaggactat     1080

ggaatggaat taagaaaagg ttcccttgag agtcctgcaa cggatgtttt tggttctaca     1140

gaggaaggtg aaaaaaggtg gaaagacttg aagaacagag ttgttgaaca taatattaga     1200

ataatggcca agtattatac tcggataaca atgaaaagga tggcacagct tctggatcta     1260

tctgttgatg agtccgaagc ctttctctca aatctagtag ttaacaagac catctttgct     1320

aaagtagaca gattagcagg aattatcaac ttccagagac ccaaggatcc aaataattta     1380

ttaaatgact ggtctcagaa actgaactca ttaatgtctc tggttaacaa aactacgcat     1440

ctcatagcca aagaggagat gatacataat ctacaataag ggtcttagtg ctttagaaaa     1500

aagttaaaat tggaagtcat taaaaaaaga ctgttataat ggtgtatatg ttggggtttt     1560

ttttctaagc ttctttgtct taaattttaa aatagtgaat atgtttgaga ctccctttga     1620

cctttcagtt ccccaagttc attgttaact ttgcatttgc aattggtgca aaaatacaga     1680

tttctgtcgt ctgaatacac aaaaagttgt gtcataactt acccagatat gtttttctat     1740

catttgaaac ctttttagct actgtttgtt ttcattcaac taacaaacat attccaataa     1800

taaaagcagt atatacatat ttcctttcta cagttacctc tgattctcaa cattttgtgg     1860

ggtagtgatt tggcaagtgt tttttaaata aaacaaatct cattgtaaag ctatcagtca     1920

tttagtagaa tagaaaagca acatagagca tacaagaaca tttgggatag agttgtgatt     1980

tgtgaagaat ttgtactttg atattgtggc ggaaagtcta gactgagtgt gtatgctggt     2040

aaactgtaga cttttttttt tttttttttg agtccggctg gttccaatca cagtagcttg     2100

attgctttca gccctcatcc tctcacttga tcagttgttc aacagaatca gctgacataa     2160

ttgacacagt ttattgggtg ttaagtccgc tctataggga tagtgactac tttttttttt     2220

tttttttttt tgctcttctt cctctcccct ttctttatat gggtttaaat ttaacataaa     2280

gttgttttta taaggcttat ttgtggcttt aacttgtaag tctgattaca tcattattgt     2340

tccaaattca ttatctctgt aggaactttt agttccatta tatgaacact ggataaccta     2400

atttttttta atgctttaaa aaaatggcaa aaagacgtca ggccaccctc atagtaagtg     2460

gtgtagtatt aaaatatttt cacggaatta aaagtagctt gctgtcaaag aaacacctga     2520

gatgaattgg tgtgaacgaa ttttgcaagt ttaatttgat ttatttcaga gaaaatagaa     2580

aaaacaatgt tagaaggtta tttaaaatga tacttaaata aagaaagtgt gaggtctact     2640

ttaaaaaaat tcaaatgaag agaaaaagaa aaacagcatt ctagaaatgg catttctcct     2700

aattaatttt ccacttaatg gaagattatc aattgtccta ttttatgatc ccaggactga     2760

agacagttgt gggatatctg tcatatttat cctgtgagtc attgtgaata atgacataca     2820

gtactgaagt aatctgattt tattctttgg aaattcaatg cattggtcac actaataaca     2880

tcaacatctg ctatcactta tctttttaaa actaaccaaa aaaggccggg tgcagtggat     2940

cccagcactt tgggaggcca aggcgggtgg atcatctaag gtcaggattt cgagactagc     3000

ctggccaaca tggcaaaacc ctgtctctac taaaaaaaat acaaaaattt gccgggcgtg     3060

gtggcgtgtg cctgtagtcc cagttacttg ggaggctgag gtgggagaat tccttgaagc     3120

caggaggcgg aggttgcagt gagccaagat cacaccattg cactccagcc tgggtgacag     3180

agtgagactc cgtctcaaaa aaaaaaaaac aaaactggaa agttcagaaa cagaagttca     3240

cactaacaga gtatggtttt aattttcctt tgaatgaaaa ggatagaaga taaaattgtg     3300

tattgttaac atgtaaataa aattggagct aatttgaaac tagcttctca ataacttcat     3360

ctttctagag actcattacc tgtgggcttg tcaaacctgg actatttggc caaataggtt     3420

gctatagaga ttgcaagtgt tcctcctctt tatttttttc atattttttg agacggagtt     3480

tcactcttgt tgcccaggct ggattgcagt gtcacgatct cggctcactg caacctttgc     3540

ctcccatatt caagcagttc tcctgcctca acctcccaag tagctgggat tataggcgcc     3600

tgccaccaca cctagctaat ttttgtgttt ttagtagaga tggtttcatc atgttggccg     3660

ggctggtctc aaactcctga cctcaggtga tccacccgcc ttggctgccc aaagtgctgg     3720

gattacaggc atgagccact gcacccaact cctctttcgt ctttctttaa cacacactag     3780

gctctttgtg tattatgatt cagtgctatt tgtaactgtg tcccagtgac caaattgcac     3840

tcgactcgat cagctgttca tccatttcgt gttttttcct gtcaaacatt aatccagcaa     3900

atatatgagg tatttaccaa tttattttct tagtattaca aaataattca ttagcataaa     3960

gtacaatagt gaaatatttg agttgttcgg aacctcaatt aatcctgttt tacatttcag     4020

acctaaagct ggcaatcagg agaagaagca ctttgtttta aatgtggaga agataacact     4080

tgattccatt tcattgtcat tagtgtatta accagcagga gaggtgatga gccatttttc     4140

aaatgaaata ccttttattt ccatataatt tttttatttt agagttcaat agctgtttct     4200

atgattatcc tcaatttcca tatgttactg aatctgaaaa acatctttaa aattcaaaca     4260

gttccatttt ctctcttgta agtgttaaat gtgataaaag tacatatttt aaattgtttt     4320

cagctcttgg atatagcagc aataaaaaca ctaatttgtg ggtatttaag aaaacctgga     4380

gaataaactc atactttaaa agatcaaaaa aaaaaaaaaa aaa                       4423


<210>  2263
<211>  2851
<212>  DNA
<213>  homo sapiens

<400>  2263
gggccagcgg cgcggctgaa gcgagggcgg ggagggaaag cgagcggcgc ctgcgccccg       60

gcggtggacg ggcccggtcg tgggcgggga ttggggcgga gcctgaccgt tacgcgcagc      120

cccgcccccg cggcctcgtc gctcctgctg aggcggtagc cgcttttcgt cgactcttac      180

cggttggctg ggccagctgc gccgcggctc acagctgacg atgggggacc ccagcaagca      240

ggacatcttg accatcttca agcgcctccg ctcggtgccc actaacaagg tgtgttttga      300

ttgtggtgcc aaaaatccca gctgggcaag cataacctat ggagtgttcc tttgcattga      360

ttgctcaggg tcccaccggt cacttggtgt tcacttgagt tttattcgat ctacagagtt      420

ggattccaac tggtcatggt ttcagttgcg atgcatgcaa gtcggaggaa acgctagtgc      480

atcttccttt tttcatcaac atgggtgttc caccaatgac accaatgcca agtacaacag      540

tcgtgctgct cagctctata gggagaaaat caaatcgctc gcctctcaag caacacggaa      600

gcatggcact gatctgtggc ttgatagttg tgtggttcca cctttgtccc ctccaccaaa      660

ggaggaagat ttttttgcct ctcacgtttc tcctgaggtg agtgacacag cgtgggcatc      720

agcaatagca gaaccatctt ctttaacatc aaggcctgtg gaaaccactt tggaaaataa      780

tgaaggtgga caagagcaag gaccaagtgt ggaaggtctt aatgtaccaa caaaggctac      840

tttagaggta tcctctatca taaaaaagaa accaaatcaa gctaaaaaag gccttggggc      900

caaaaaagga agtttgggag ctcagaaact ggcaaacaca tgctttaatg aaattgaaaa      960

acaagctcaa gctgcggata aaatgaagga gcaggaagac ctggccaagg tggtatctaa     1020

agaagaatca attgtttcat cattacgatt agcctataag gatcttgaaa ttcaaatgaa     1080

gaaagacgaa aagatgaaca ttagtggcaa aaaaaatgtt gactcagaca gactcggcat     1140

gggatttgga aattgcagaa gtgttatttc acattcagtg acttcagata tgcagaccat     1200

agagcaggaa tcacccatta tggcaaaacc aagaaaaaag tataatgatg acagtgacga     1260

ttcatatttt acttccagct caagttactt tgacgagcca gtggagttaa ggagcagttc     1320

tttctctagc tgggatgaca gttcagattc ctattggaaa aaagagacca gcaaagatac     1380

tgaaacagtt ctgaaaacca caggctattc agacagacct actgctcgcc gcaagccaga     1440

ttatgagcca gttgaaaata cagatgaggc ccagaagaag tttggcaatg tcaaggccat     1500

ttcatcagat atgtattttg gaagacaatc ccaggctgat tatgagacca gggcccgcct     1560

agagaggctg tcggcaagtt cctccataag ctcggctgat ctgttcgagg agccgaggaa     1620

gcagccagca gggaactaca gcctgtccag tgtgctgccc aacgcccccg acatggcgca     1680

gttcaagcag ggagtgagat cggttgctgg aaaactctcc gtctttgcta atggagtcgt     1740

gacttcaatt caggatcgct acggttctta atactgaagt catgatgtgt atttcctgga     1800

gaaattcctc tttaaatgaa caagtaacca catctcaggc ggcagtgaag tccagatagt     1860

tttgcagatt gttttgctac tttttcatat ggtatatgtt tctgattttt aatatttctt     1920

ttgagaaatt ctgagttctg atgtaggagc tttcctgtga tttctgtttc acgttccttc     1980

ctgtcacacc ctcctttggc gtctctgtgt atatccttgc tttattttct tggaaccttt     2040

gatttcaaca ctgagggcct ggagacctcg gctcctcctg ctcctgaacc aggaggcttc     2100

atgtggggga ggaggagagg tctccatgtg acacatgggc tcagggctgc cagaatcagc     2160

ggatgctgga tgggcctgca gaaacaacac tcaccacaca cacttccttc aaaagaccaa     2220

aagtgactgg tgtctcgtgt gacagattgc ttcatttatg tttctacata gtaaggtgac     2280

tgccaaataa tatttgaagt catctgtctc tttgtaaatt attttatatg acctataaat     2340

ttaaaaatgt ttttcagtga gtgcttttaa caaacttaag cttctgccct gccaagggaa     2400

ttaatgttat cttgtgaaag gtgttgctgt ttgaattgat gagaaatgga agatgagaac     2460

tccctaagag ttctcataat aaatcatctc atcacaaatc aatacggtat acagagttaa     2520

agtggaatga ggtaagaaga tacagctaca gaaaatagtt gcgtgtatgg gagaacagtc     2580

attgtaattg ggtagttttg ttaataaata tttttaaatc ttgcttttca gaaattaccg     2640

aatgtgtata aacaaataaa gaaaaataat ttagctgtgt tttagacagc attagaatat     2700

attgttcagc acagtaaaat atatttgaaa tttgataagc caaaaatgtg gttttgaatg     2760

aatattttgt gaatctttct taaaagctca aatttgtaga cttctaaata gaataaacac     2820

ttgcagcaga tggaaaaaaa aaaaaaaaaa a                                    2851


<210>  2264
<211>  2504
<212>  DNA
<213>  homo sapiens

<400>  2264
ttattttgat tcaccgcaga gggcggtcta cgagagcgca gagccccact cggccagcgg       60

ggtctggcgg gggacctgtc gcgctgaaag ctccagggta gggccgacgc ccatcaggct      120

gggcatccgt tcgggatgcg caggttgcga tctgcaaccg gcggcgccac gcccaggcgg      180

gcggagcgcg gttcccggag tctcgcgccc gcggtcatgt gacacagcga agatggcgtc      240

gcccggctgc ctgtggctct tggctgtggc tctcctgcca tggacctgcg cttctcgggc      300

gctgcagcat ctggacccgc cggcgccgct gccgttggtg atctggcatg ggatgggaga      360

cagctgttgc aatcccttaa gcatgggtgc tattaaaaaa atggtggaga agaaaatacc      420

tggaatttac gtcttatctt tagagattgg gaagaccctg atggaggacg tggagaacag      480

cttcttcttg aatgtcaatt cccaagtaac aacagtgtgt caggcacttg ctaaggatcc      540

taaattgcag caaggctaca atgctatggg attctcccag ggaggccaat ttctgagggc      600

agtggctcag agatgccctt cacctcccat gatcaatctg atctcggttg ggggacaaca      660

tcaaggtgtt tttggactcc ctcgatgccc aggagagagc tctcacatct gtgacttcat      720

ccgaaaaaca ctgaatgctg gggcgtactc caaagttgtt caggaacgcc tcgtgcaagc      780

cgaatactgg catgacccca taaaggagga tgtgtatcgc aaccacagca tcttcttggc      840

agatataaat caggagcggg gtatcaatga gtcctacaag aaaaacctga tggccctgaa      900

gaagtttgtg atggtgaaat tcctcaatga ttccattgtg gaccctgtag attcggagtg      960

gtttggattt tacagaagtg gccaagccaa ggaaaccatt cccttacagg agacctccct     1020

gtacacacag gaccgcctgg ggctaaagga aatggacaat gcaggacagc tagtgtttct     1080

ggctacagaa ggggaccatc ttcagttgtc tgaagaatgg ttttatgccc acatcatacc     1140

attccttgga tgaaacccgt atagttcaca atagagctca gggagcccct aactcttcca     1200

aaccacatgg gagacagttt ccttcatgcc caagcctgag ctcagatcca gcttgcaact     1260

aatccttcta tcatctaaca tgccctactt ggaaagatct aagatctgaa tcttatcctt     1320

tgccatcttc tgttaccata tggtgttgaa tgcaagttta attaccatgg agattgtttt     1380

acaaactttt gatgtggtca agttcagttt tagaaaaggg agtctgttcc agatcagtgc     1440

cagaactgtg cccaggccca aaggagacaa ctaactaaag tagtgagata gattctaagg     1500

gcaaacattt ttccaagtct tgccatattt caagcaaaga ggtgcccagg cctgaggtac     1560

tcacataaat gctttgtttt gctggtgatt taaccagtgc ttggaaaaat cttgcttggc     1620

tatttctgca tcatttctta aggctgcctt cctctctcag tacgttgccc tctgtgctat     1680

catcttatca tcaattatta gacaaatccc actggcctac agtcttgctt ctgcagcacc     1740

cactttgtct cctcaggtag tgatgaatta gttgctgtca caaaaggagg gaagtagcac     1800

ccaaattaag ttgcttaaga gaggaaatgt acatcttgta taacttaggg agcgaagaaa     1860

atgtaggcgc gaaagtgaaa agtgaggcag ctagttcttc ctattccatt ctcgaccaac     1920

ctgccctttc ttaatatgac tagtggtctt gatgctagag tcaacttact ctgttgctgg     1980

ctttagcaga gaataggagg aaccatatga aaaagatcag gctttctgac ttccatcccc     2040

aaaacacatt taccagcata ctccaaactg tttctgatgt gttccatgag aaaaggattg     2100

tttgctcaaa aagcttggaa aatactacac actccctttc tccttctgga gatcaaccca     2160

cattagagtg tctaaggact cctgagaatt cctgttacag taaacaaaac taacgtaatc     2220

taccatttcc tacactattt gagcatggaa atcatagtcc ccactctgtg aaaacttaac     2280

gctttttgga agacatttct gtagcatgtc agtttggaga aatgatgagc tacgccttga     2340

tgaaagaacc gtgttggtgc tgctaagttt agccattatg gtttttcctt tctctctctt     2400

aagccttatt cttcaactaa aagatgagga ttaagagcaa gaagttgggg gggatgtgaa     2460

aataatttta tgaggttgtc taaaataaag agtagtttct tatc                      2504


<210>  2265
<211>  367
<212>  DNA
<213>  homo sapiens

<400>  2265
atgtctggcc gcggtaaggg cggaaagggt ctaggtaagg gtggcgccaa gcgtcaccgt       60

aaggtattgc gtgacaatat ccaaggaatc accaagcccg ctatccgccg cctggctcgc      120

cgcggcggcg tcaagcgtat ttctggcctc atttatgagg aaactcgcgg agtgctgaaa      180

gttttcctgg aaaatgtaat ccgcgatgct gtcacctaca cggaacacgc caaacgcaag      240

acagtcacag ccatggacgt ggtgtacgcg ctcaagcgcc agggacgcac tctttatggc      300

ttcggcggct gagcttacct ctacagtaca ctaccgcaaa accaacggcc cttttcaggg      360

ccaccta                                                                367


<210>  2266
<211>  390
<212>  DNA
<213>  homo sapiens

<400>  2266
atgtctggtc gcggcaaagg cggaaaaggc ttggggaagg gtggtgctaa gcgccatcgt       60

aaggtgctcc gggataacat ccagggcatt acaaaaccgg ctattcgccg tttggctcgg      120

cgcggtggcg tcaagcgcat ttccggtctt atctatgagg agactcgagg tgtgcttaag      180

gttttcttag agaacgttat tcgagacgcc gtcacctata cggagcacgc caagcgcaaa      240

actgtcacag ccatggatgt agtatatgcc ctaaaacgtc aggggcgcac tctgtatggc      300

ttcggcggct gaatctaaga atacgcggtc tcctgagaac ttcaaaaaac aaaaacaaaa      360

aaacccaaag gcccttttca gggccgctca                                       390


<210>  2267
<211>  372
<212>  DNA
<213>  homo sapiens

<400>  2267
atgtctggac gtggtaaggg cgggaagggt ttgggtaagg ggggtgccaa gcgccaccgc       60

aaggtgttgc gtgacaacat ccagggcatc accaagccgg ccatccggcg tctggcccgg      120

cgtggcggtg tgaagcggat ctctggtctg atctacgagg agactcgcgg ggtgctcaag      180

gtgtttttgg agaacgtgat ccgtgacgct gtcacctata cggagcacgc caagcgcaag      240

acagtcactg ccatggacgt ggtctacgcg cttaagcgcc agggacgcac cctttatggc      300

tttggcggtt aaggttgctg atttctccac agcttgcatt tctgaaccaa aggccctttt      360

cagggccgcc ca                                                          372


<210>  2268
<211>  368
<212>  DNA
<213>  homo sapiens

<400>  2268
atgtctggta gaggcaaagg tggtaaaggt ttaggaaagg gaggcgccaa gcgccatcgc       60

aaagtgctgc gtgacaacat acagggcatc acgaagcccg ccatccgtcg cttggcccga      120

cgcggcggcg tgaaacgcat ttcgggcctc atttatgagg agacccgcgg tgttcttaag      180

gtgttcctgg agaatgtgat acgggacgcc gtaacctaca cggagcacgc caagcgtaag      240

acagtcactg caatggatgt tgtctacgcg ctcaagcgcc agggacgcac tctgtacggc      300

tttggtggct gagcctcacc ccggcttttt atttaacagc tcacccataa aaggcccttt      360

tcagggcc                                                               368


<210>  2269
<211>  357
<212>  DNA
<213>  homo sapiens

<400>  2269
atgtctggtc gcggcaaagg cggtaaaggt ttgggtaagg gaggtgccaa gcgtcaccga       60

aaagtgctgc gggataacat ccaaggcatc accaaaccgg ccattcggcg ccttgctagg      120

cgtggtgggg ttaagcgaat ttccggtttg atttatgagg agactcgtgg cgttctcaag      180

gtgtttctgg agaacgtgat ccgggacgcc gtgacctaca cggagcacgc caagcgcaag      240

actgtcactg ccatggatgt ggtttacgcg ctcaagcgtc aaggacgcac tctgtacggc      300

ttcggcggtt aatcttttcg tcagttttct tccaatggcc cttttcaggg ccgccca         357


<210>  2270
<211>  374
<212>  DNA
<213>  homo sapiens

<400>  2270
atgtctggcc gtggtaaagg tggaaaaggt ttgggtaagg gaggagctaa gcgtcatcgc       60

aaggttttgc gcgataacat ccagggcatc actaagccag ctatccggcg ccttgctcgt      120

cgcggcggtg tcaagcgaat ttctggcctt atctatgagg agactcgtgg tgttctgaag      180

gtgttcctgg agaacgtgat tcgtgacgct gtcacttaca cagagcacgc caaacgcaag      240

accgtgacag caatggatgt ggtctacgcg ctgaagcgac agggacgcac tctttacggc      300

ttcggtggct aaggctcctg cttgctgcac tcttattttc attttcaacc aaaggccctt      360

ttcagggccg ccca                                                        374


<210>  2271
<211>  377
<212>  DNA
<213>  homo sapiens

<400>  2271
atgtctggtc gcggcaaagg cggaaaggga ctgggtaaag gaggcgctaa gcgtcaccgt       60

aaggtcctgc gagataacat ccagggcatt accaagcctg ccatccggcg ccttgctcgt      120

cgcgggggtg tcaagcgcat ttctggtctc atctacgagg agactcgcgg ggttctgaag      180

gtgtttctgg aaaacgtgat tcgtgatgct gtgacttaca cggagcacgc caaacgcaag      240

acagtgacag cgatggatgt ggtctacgcg ctgaagagac agggacgcac tctttacggc      300

ttcggcggct aatgctaccg cttaaacgac tcagcatctc gacttcccaa atcaaaggcc      360

cttttcaggg ccgccca                                                     377


<210>  2272
<211>  6010
<212>  DNA
<213>  homo sapiens

<400>  2272
ctctcttcct cccttcctag agagggaaca acattcatgt gacgggcccc tctgcttctc       60

ccccgcccca tcatctccag cgcgtggtgg gggaactgct ggggaaggcg attggcatcg      120

atctctccat cccttccgag gcccgacttc ggaattgtct tagaagaaag aaggcaagcc      180

accattttac ccacgtaaat atatgaatat atttctgaca ttgaggtgtt ccagaagatg      240

ataaagaaat gatagcagct ccagaaatac caactgattt taatctacta caggagtcag      300

aaacacattt ttcttctgac acagattttg aagatatcga aggaaaaaac caaaagcaag      360

gcaaaggcaa aacttgtaaa aaaggcaaaa agggcccagc agaaaagggc aaaggtggaa      420

atggaggagg aaaacctcct tctggtccaa accgaatgaa tggtcatcac caacagaatg      480

gagtggaaaa catgatgttg tttgaagttg ttaaaatggg caagagtgct atgcagtcgg      540

tggtagatga ttggatagaa tcatacaagc atgaccgaga tatagcactt cttgacctta      600

tcaacttttt tattcagtgt tcaggctgta aaggagttgt cacagcagaa atgtttagac      660

atatgcagaa ctctgagata attcgaaaaa tgactgaaga attcgatgag gatagtggag      720

attatccact taccatggct ggtcctcagt ggaagaagtt caaatccagt ttttgtgaat      780

tcattggcgt gttagtacgg caatgtcaat atagtatcat atatgatgag tatatgatgg      840

atacagtcat ttcacttctt acaggattgt ctgactcaca agtcagagca tttcgacata      900

caagcaccct ggcagctatg aagttgatga cagctttggt gaatgtggca ctaaatctta      960

gcattaatat ggataataca caaagacaat atgaagcaga acggaataaa atgattggaa     1020

aacgagccaa tgagaggcta gaactcctgc tacaaaagcg gaaagagctt caggaaaatc     1080

aagatgaaat agaaaatatg atgaatgcaa tatttaaagg agtgtttgta catagatacc     1140

gtgatgcgat agctgaaatt cgagctattt gcattgaaga gattggcatt tggatgaaga     1200

tgtatagtga tgcctttctt aatgacagtt atttaaaata tgttggttgg actatgcatg     1260

ataagcaagg tgaagtaaga ctcaaatgtc ttactgctct acaagggctt tattataaca     1320

aagagcttaa ttccaaactg gaacttttta ccagtcggtt caaggataga attgtgtcta     1380

tgacccttga caaagaatat gatgttgcag tacaagcaat aaaattactc actcttgttt     1440

tacagagtag tgaagaagtt ctcactgcag aagattgtga aaatgtctat catctggttt     1500

attcagctca ccggccagta gcagtagcag ctggagaatt tctctacaaa aagctcttca     1560

gtcgtagaga tccagaggag gatggaatga tgaaaagaag aggaagacaa ggtccaaatg     1620

ccaaccttgt taagacattg gtttttttct ttctagaaag tgagttacat gagcatgcag     1680

cataccttgt ggatagcatg tgggactgtg ctactgagct gctgaaagac tgggaatgta     1740

tgaatagctt gttactggaa gagccactta gtggagagga agcactaaca gataggcaag     1800

agagtgctct gattgaaata atgctttgta ccattagaca agcggctgaa tgtcatcctc     1860

ccgtgggaag agggacagga aaaagggtgc ttacagcaaa ggagaagaag acacagttgg     1920

atgataggac aaaaatcact gagctttttg ccgtggccct tcctcagtta ttagcaaaat     1980

actctgtaga tgcagaaaag gtgactaact tgttgcagtt gcctcagtac tttgatttgg     2040

aaatatatac cactggacga ttagaaaagc atttggatgc cttattgcga cagatccgga     2100

atattgtaga gaagcacaca gatacagatg ttttggaagc atgttctaaa acttaccatg     2160

cactctgtaa tgaagagttc acaatcttca acagagtaga tatttcaaga agtcaactga     2220

tagatgaatt ggcagataaa tttaaccggc ttcttgaaga ttttctgcaa gagggtgaag     2280

aacctgatga agatgatgca tatcaggtat tgtcaacatt gaagaggatc actgcttttc     2340

ataatgccca tgacctttca aagtgggatt tatttgcttg taattacaaa ctcttgaaaa     2400

ctggaatcga aaatggagac atgcctgagc agattgttat tcacgcactg cagtgtactc     2460

actatgtaat cctttggcaa cttgctaaga taactgaaag cagctctaca aaggaggact     2520

tgctgcgttt aaagaaacaa atgagagtat tttgtcagat atgtcaacat tacctgacca     2580

acgtgaatac tactgttaag gaacaggcct tcactattct gtgtgatatt ttgatgatct     2640

tcagccatca gattatgtca ggagggcgtg acatgttaga gccattagtg tatacccctg     2700

attcttcatt gcagtctgag ttgctcagct ttattttgga tcatgtcttc attgaacagg     2760

atgatgataa taatagtgca gatggtcagc aagaggatga agccagtaaa attgaagctc     2820

tgcacaagag aagaaattta cttgcagcat tttgtaagct aattgtatat actgtggtgg     2880

agatgaatac agctgcagat atcttcaaac agtatatgaa gtattataat gactatggag     2940

atatcatcaa agaaacaatg agtaaaacaa ggcagataga caaaattcag tgtgctaaga     3000

cccttattct cagtctgcaa cagcttttta atgaaatgat acaagaaaat ggctataatt     3060

ttgatagatc atcctctaca tttagtggca taaaagaact tgctcgacgt tttgctttaa     3120

cttttggact tgatcagttg aaaacaagag aagccattgc catgctacac aaagatggca     3180

tagaatttgc ttttaaagag cctaatccgc aaggggagag ccatccacct ttaaatttgg     3240

catttcttga tattctgagt gaattttctt ctaaactact tcgacaagac aaaagaacag     3300

tgtatgttta cttggaaaag ttcatgacct ttcagatgtc actccgaaga gaggatgtgt     3360

ggcttccact gatgtcttac cgaaattctt tgctagctgg tggtgatgat gacaccatgt     3420

cagtcattag tggaatcagc agccgggggt caacagtacg gagtaaaaaa tcaaaaccat     3480

ctacaggaaa acggaaagtg gttgagggca tgcagctttc actcactgaa gaaagtagta     3540

gtagtgacag tatgtggtta agcagagaac aaacactgca cacccctgtt atgatgcaga     3600

caccacaact cacctccact attatgagag agcccaaaag attacggcct gaggatagct     3660

tcatgagtgt ttatccaatg cagactgaac atcatcaaac acctcttgat tataatcggc     3720

gtggcacaag cctaatggaa gatgatgaag agccaattgt ggaagatgtt atgatgtcct     3780

cagaagggag gattgaggat cttaatgagg gaatggattt tgacaccatg gatatagatt     3840

tgccaccatc aaagaacaga cgagagagaa cagaactgaa gcctgatttc tttgatccag     3900

cttcaattat ggatgaatca gttcttggag tgtcaatgtt ttaataccag tacacaatta     3960

aatctgtggt gaagtcattt tctaagtgga agaggaaatt ttaaagtgtg gtagatacag     4020

tgaaattctg tacagatttt tctctaagga gaatatgaca tgcttatgct taccaagatc     4080

aagtgcattg aggggcagtt ttgtttgcct gaataaacgt aaaggacaag taaacaattt     4140

gatgataagc tacagttttt cttagaaagt aaatatttta tttatgcgct gttagttggc     4200

ttttgaatcg attatttcat gctttttttt aaaaaaaaaa aaaaacaaaa taacaatctg     4260

aagaggcatt tggtacagat atgaattctc ttacatttat ttactggttg tactaaataa     4320

tgatgacctc tgctggattt ctgtttacat ccagaaaaca atgttaagga tgtatttatt     4380

cccctaccct gaagaaagtg taggatagaa ttgtttttag cattctaaat ttaaatgctt     4440

aaaacgtcaa tcaacaaaac tttgttttaa atattgtaat tgtggagaaa agtaaactta     4500

taagcagaac ttttacaatt ttttcatcta aaagtatttt aagatatttt taaaatccaa     4560

gagcttctct atacttttca gaaatatcca gatgcagtga actgccagaa ggtaaccagt     4620

ctcaaacatg cttatcccat tatcaaccct gaaagtttgc ttgtccttta agataaaaat     4680

gtaatgttgt gatattcctt ccagtaatgc cactgtattt tgtctccaaa taaaagaagc     4740

ttattgtagt atgtttgcag aaaaattcta aacaaaaatt atacagctta ttagagtgtg     4800

ggaataggga tctaaatttt aaataaaatt atatatatat ataaattggt gctgatttta     4860

taattgcgca gtttgtttag ttttttctta cttttaaatt ccaacttaaa attatgaggt     4920

ttcagaaata tattgaaagt ttaacaatgt ttaaaaatag aaaagcatga gtgttcatgc     4980

tttaaaatga tttttaaatt tgtattttat attgttttat ctatctgtct ttgcaagcag     5040

tcttcaggtt aaagatactt ctaacaggtt acagtacatt tcctctgtat gtaaattaga     5100

tgggataata gaattcataa cccataatat tctttgaaag ctaagcttta aacttcattt     5160

tatgtccttt cacaaataaa ttagtttaaa acagaaagtg gctacttgcc attttgacat     5220

caactcattt tgcgaggctt aggcagctag acatcgttta aaacaaaata ttaacttata     5280

ttacatgtgt atctatctat tgtcagtcgt ctctcagttc ttgaggtata ttattttaat     5340

cattccatgc cttaatatgc ttgcaataca agaatatctt cagatgggtg aataccaaaa     5400

ggctttcagt ttttagtcag aaatcaagca ttgggctgtg gtagccaaaa accataggtt     5460

agctaaaaag atcatgatac aattatttta ttaagtcatg gttaataaca aatgaatcca     5520

gacttgtcta acagattttc catcaacaaa tattgttatg tgcaaaagta ttgcctatgt     5580

tgttttacac accactgcat taactagaac tgctgagagg actgtatata tgattttaaa     5640

cctaagttga ttttttttct cactcttgaa aggagtactt ctttgtgaaa gcagttctta     5700

cagctttgtt ttcaaccagc taaaaatgtt ttatatatta ctctaacctg ttgtcctcca     5760

cattctattg tcctaattgt actgttttct gatttgtatt tatgtcttga gacagtaact     5820

ttttgaataa aaataaacct acagtatgtt gtatgttttc tcttgtactc aaagggggag     5880

ggtggctata aatggtttgc aaatttatat ctattatcac atcttttaat gtgtttgggg     5940

aataatttat agagaatacc atcagtttat atttttaata aatcatatgt atttacaatg     6000

aaaaaaaaaa                                                            6010


<210>  2273
<211>  2538
<212>  DNA
<213>  homo sapiens

<400>  2273
gtgagcgggc ggccggccgg acagactgac gtgtgagctg catcgcggga ggcgcatggc       60

ggggatggcg ctggcgcggg cctggaagca gatgtcctgg ttctactacc agtacctgct      120

ggtcacggcg ctctacatgc tggagccctg ggagcggacg gtgttcaatt ccatgctggt      180

ttccattgtg gggatggcac tatacacagg atacgtcttc atgccccagc acatcatggc      240

gatattgcac tactttgaaa tcgtacaatg accaagatgc gaccaggatc agaggttcct      300

tggggaagac ccaccctacg aagttggaat gagaccatca gatgtgataa gaaactcttc      360

tagatgtcaa cataaccaac cttataaaga ctaaaattca tgagtagaac aggaaaatca      420

tcctgactca tgtgttgtgt tctttatttt taattttcaa agaggctctt gtatagcagt      480

ttttgtctat tttaacattg tagtcatttg tactttgata tcagtatttt cttaaccttt      540

gtgactgttt caatattacc cccgtgaaag cttttcttaa tgtaactttg agtacatttt      600

aattgccttc tatttttaaa actcaaaatc attagttggg ctttactgtt cttgctattg      660

tatggcatat acatctgcct ggatatattt ctactcttga ccaaagtttt gtaaagaaca      720

atataagatt tcgggtaggg gtatggggag ggaagatatt ttattgagaa ctacttaaca      780

aaagatttat ctgtaagctt gaactcagga gtacagtttt agctatctag actctaacag      840

cttttgcttt aaaattatta aagtgtttct taatgaaaaa gaaaagatct tgctaaagtt      900

aaaataagga acatttcacc ttttaaatat ttaattctta tgtggactta tttccagaaa      960

actttggtga taattcttga gacaaaaggt ggttaagtag cattattatg taatgcttat     1020

ataccataga gtttttaata gaagagaaat ccatttcctc cgagggtcac tattaacaat     1080

gtacttcctt aaatttagtt taatgattgt aatgggtgct gcatttgcac attgcattaa     1140

gttatgatga gacgaattgt tgttaaaaat tatagcaaaa agaaatgtaa acttggttaa     1200

aatcctttca ctctttgtat tgtttttttt aaggttttta ttccttaaat gtaaaatgac     1260

tacctaattt tttgatgtaa atacattaaa ttcaaagaga aaaaaaatca gctgatgtag     1320

cagtatatct tttccttgat ggttaaatat tgatctagta tttatattgc tgaattattt     1380

tctgtggagg accagataag cagtaagtat gtcttatcct atatgttttg caacataaaa     1440

atattgctaa ttgaaaagaa ttaggcaatt atgtgtgttg ctgggttgtt tttttgtttt     1500

tttttttttg agacggagtc ttgccctgtc gcccaggatg gagtgcaaca gcatgatctc     1560

ggttcactgc aacctccatc tcctgggatc aagtgattct cctgcctcag cctcctgaat     1620

agctgggatt acaggcacct gccaccatgc ctggctaatt ttttgtatct gtagtagaga     1680

cggggtttca ctgtgttggc caggatggtc tcaaactcct gacctcctga tccacctgcc     1740

tcggcctccc aaagtgctgg gtttacaggc gtgagccacc gcgcccggcc aaaattgagg     1800

tattttttgc cctacgtttt aaggactaga cttttgaagt attttatagt ctagaggtct     1860

caagtaatat atatgtgttt aatattttta gagccaattg ataccacaat tagataggag     1920

tagtgagaat aatatggaat tacttggttt gaagtagtta aaaattggat atggttatat     1980

ctgagctgta gtcatattat ctcaagaaaa ataatacgag gatttaacat aagatttgtt     2040

ctattaatgc ccaaatttgg ctttcctcta ctatccccca tagagaacca ctaacaagtg     2100

gatgtctaat attcctctgg tgagttgaag gcaggagaag ttgagaatca ttagtttcaa     2160

tgagtatcca ggtgacctat cctggccctc tactcagaaa ccggcaattt gtcttcactc     2220

tgagattcat taaattgctg ttgtataact gatggttatt atgaacactg acctgtgaga     2280

catatggaag ataaagtttg gtcttacagg aaatcttgag gagagtcaaa agagaaatgg     2340

gagatgtctc ttgagaggtg atcagagaag tttatgctca ctgtctgatg caaatgtctg     2400

gtctatttgt tagtaaataa cagggaaatc attttcactt tttgttaaaa ataaggtatt     2460

tacaagcata ccttgtagtt attgtgggtt cagtttcaga ccactgcaat aaagtgaata     2520

tctcaataaa gtgaaaaa                                                   2538


<210>  2274
<211>  3873
<212>  DNA
<213>  homo sapiens

<400>  2274
catctgcctg cccttctgcc atccgagcgc cctgactgcg ccacactgca ggccatggag       60

aatgagctgc cagtcccaca tacatctagc agtgcctgtg ccaccagcag taccagcggg      120

gccagtagca gcagtggctg caacaacagc agcagtggtg gaagtggccg ccccaccggg      180

ccccagattt ctgtgtacag tggtattcca gaccggcaga ccgtgcaggt gatccagcag      240

gccctgcaca gacagcccag cacggccgct cagtacctgc agcagatgta cgccgcccag      300

cagcagcacc tcatgctgca gaccgcggcg ctccagcagc agcacctcag cagcgcccag      360

ctccagagcc tggcagccgt acagcaggca agcctggtat ccaatagaca aggaagcact      420

tcaggcagca atgtgtctgc gcaggccccg gcccagtcat cttcgatcaa cctggcagcc      480

tccccagcag cagcccagct cctcaaccgg gcccagagtg tgaactctgc agcagcctca      540

ggcatcgctc agcaggctgt gctcttgggc aacacgtctt ccccagccct gactgcaagc      600

caagcacaga tgtatctgag ggcacagatg ctcatcttca cgcccacggc caccgtcgct      660

actgtgcagc ctgagctcgg cactggctcc cccgcccggc cccccacccc cgcccaggta      720

cagaacttga ccctccgaac acagcagaca ccagcggcag cagcctcggg ccccaccccc      780

actcagcctg tcctgcccag cttggccctg aaacccacgc cgggcggtag ccagcctctg      840

cctaccccag cacagagcag aaatactgct caggcttccc ctgcaggtgc caagcctggc      900

atagctgaca gtgtgatgga gccacacaag aaaggagatg gcaacagcag tgtgccaggg      960

agcatggaag gccgggctgg gctcagccgg acggttcctg ctgtggctgc ccaccccctc     1020

attgcaccag cctatgctca gctgcagcca caccagctcc tcccacagcc atcctcaaag     1080

cacctgcagc cccaatttgt gatccagcag cagccacagc cacaacagca gcagccgccg     1140

ccccagcagt cacggcctgt gctccaagct gagccccacc cccagctcgc ctcagtctct     1200

ccaagcgtgg ccctccagcc cagctcagag gcccatgcca tgccactagg cccggttaca     1260

cccgccctgc cactccagtg tcccactgcc aacctgcaca agcctggcgg cagtcagcag     1320

tgtcaccctc ccacacctga tactgggcct cagaatggac atcccgaggg cgtgccccac     1380

acccctcaac gcaggttcca gcacacttca gctgtcatct tacaactgca gcctgcttca     1440

ccaccccagc agtgtgtccc tgatgactgg aaagaagtgg caccagggga gaaaagtgtg     1500

cctgagacgc ggtctggccc atcaccacat cagcaggcta ttgtcactgc catgcctggt     1560

ggcctgcctg tacccacgag ccctaacatc cagccgtccc cagctcacga gacagggcag     1620

ggcattgttc atgcactgac cgacctcagc agccccggca tgacctcagg gaacggaaac     1680

tctgcctcca gcatcgccgg cactgccccc cagaatggtg agaataaacc accacaggcc     1740

attgtgaaac cccaaatcct gacgcatgtt atcgaagggt ttgtgatcca ggagggggcg     1800

gagcctttcc cggtgggacg ctcgtccctg ctggtgggga atctcaagaa gaagtatgca     1860

caggggttcc tgcctgagaa acttccacag caggatcaca ccaccaccac tgactcggag     1920

atggaggagc cctatctgca agaatccaaa gaggagggtg ctcccctcaa actcaagtgt     1980

gagctctgtg gccgggtgga ctttgcctat aagttcaagc gttccaagcg cttctgttcc     2040

atggcttgtg caaagaggta caacgtggga tgcaccaaac gggtgggact tttccactca     2100

gaccggagca agctgcagaa ggcaggagct gcgacccaca accgccgtcg ggccagcaaa     2160

gccagtctgc caccacttac caaggatacc aagaagcagc caacaggcac tgtgcccctt     2220

tcggttactg ctgctttgca gctaacacac agccaggaag actccagccg ttgctcagat     2280

aactcaagct atgaggaacc cttgtcaccc atctcagcca gctcatctac ttcccgccgg     2340

cgacaaggcc agcgggacct ggagctcccc gacatgcata tgcgggacct ggtgggcatg     2400

ggacaccact tcctgccaag tgagcccacc aagtggaatg tagaagacgt ctacgaattc     2460

atccgctctc tgccaggctg ccaggagata gcagaggaat tccgtgccca ggaaatcgac     2520

gggcaagccc tgctgctgct caaggaggac cacctgatga gcgccatgaa catcaagctg     2580

gggcccgccc tgaagatcta cgcccgcatc agcatgctca aggactccta gggctggtgg     2640

cagccaggat tctggcccag ggcgcctcct cccgactgag cagagccaga cagacattcc     2700

tgaggggccc agaaatgggg ccggttggag ggcaggggct ctccctaggg gcatagctgg     2760

tgaggaggtc tgggcacctc ctccatggct ctcaggggcc tttcatttct gtgggagggg     2820

cagagaggta ggtggcacag aagatggggc tttatgcttg taaatattga tagcactggc     2880

ttcctccaaa gtcccaatac tctagccccg ctctcttccc ctctttctgt cccccatttt     2940

ccagggggta tatggtcagg gctccccaac ctgagttggg ttacttcaag ggcagccagc     3000

aggcctggat ggaggcctag aaagcccttg ccttccttcc tcccacttct ttctccaggc     3060

ctggttaact cttccgttgt cagcttctcc cccttcagcc tgtttctgca gcagccaggg     3120

ttctcccccc tacaccctct gcaggtggag agagagaagc tgggcccagc cgggccgtgc     3180

ctgctggcac agacgcctta acgctgtgtg tatgactgtg tgactgtgtg ggagcctgga     3240

ctgacagata ggccaagggc tactctctgg catctccagg tgttttgtag caaacagcca     3300

cttagtgctt tgtcctggac tccactcagc ctcaggatgg ggaatagcca agaatggcag     3360

cctcagcgca gaggcaaggt cagaaagaga cggcgcttca gagtttcctt tccagacacc     3420

cctccccgca ctgtgaagtt cccctgaccg ccctcctggt tcacaaagag cattaagaaa     3480

gctgcggtgg tctgagcaac atagcccaaa gggctgagcc tcctggcctg cctgcccgcc     3540

caccctggga gtcccagtgg tgaggctcag agaactgcta aggggaaaga acagctggag     3600

tttctgttga tgtgaagaag gcagctcttg gcctcccact cccacacttc tttgcctata     3660

aatcttccta gcagcaattt gagctacctg aggaggaggc agggcagaaa gggcgagggc     3720

ctgcctctga cctgccgtgt cctttgcagg aaggaggtag gcacctttct gagcttattc     3780

tattccccac ccacaccccc aggcagggtt ggaaatgaag gactttttta acctttgttt     3840

tgttttttaa aaataaatct gtaaaatctg tct                                  3873


<210>  2275
<211>  4315
<212>  DNA
<213>  homo sapiens

<400>  2275
gccggaaagg acccggcctc gagatggcag agcggaggcg ttccctgggc tgagctgagc       60

acctcctccc tgagacagca gcggtctaac ccccggcgcg ggagggaccc agccaggggg      120

ctgtcctagt agattccggc attgcctcca ccccgctgtg gcggagacgc agagggcggg      180

tcgcgctcga gggtcaggga ggagagtgac ccggccctgg tccagggccc tccctgcccg      240

ccttggggcc agaactccag ccctggggag tgggcagggc ctgttttccg tgcctcacgc      300

cctgcttttc gcctccttca gcgctgtctg ctagctgctt ttcctgctct ctctccctgg      360

aggcgaaccc ttgtgctcga gatggcagcc accctgctca tggctgggtc ccaggcacct      420

gtgacgtttg aagatatggc catgtatctc acccgggaag aatggagacc tctggacgct      480

gcacagaggg acctttaccg ggatgttatg caggagaatt atggaaatgt tgtctcacta      540

gattttgaga tcaggagtga gaacgaggta aatcccaagc aagagattag tgaagatgta      600

caatttggga ctacatctga aagacctgct gagaatgctg aggaaaatcc tgaaagtgaa      660

gagggctttg aaagcggaga taggtcagaa agacaatggg gagatttaac agcagaagag      720

tgggtaagct atcctctcca accagtcact gatctacttg tccacaaaga agtccacaca      780

ggcatccgct atcatatatg ttctcattgt ggaaaggcct tcagtcagat ctcagacctt      840

aatcgacatc agaagaccca cactggagac agaccctata aatgttatga atgtggaaaa      900

ggcttcagtc gcagctcaca ccttattcag catcaaagaa cacatactgg ggagaggcct      960

tatgactgta acgagtgtgg gaaaagtttt ggaagaagtt ctcacctgat tcagcatcag     1020

acaatccaca ctggagagaa gcctcacaaa tgtaatgagt gtggaaaaag tttctgccgt     1080

ctctctcacc taatccaaca ccaaaggacc cacagtggtg agaaacccta tgagtgtgag     1140

gagtgtggga aaagcttcag ccggagctct cacctagctc agcaccagag gacccacacg     1200

ggtgagaaac cttatgaatg taacgaatgt ggccgaggct tcagtgagag atctgatctc     1260

atcaaacact atcgagtcca cacaggggag aggccctaca agtgtgatga gtgtgggaag     1320

aatttcagtc agaactccga ccttgtgcgt catcgcagag cccacacggg agagaagcca     1380

taccactgta acgaatgtgg ggaaaatttc agccgcatct cacacttggt tcagcaccag     1440

agaactcaca ctggagagaa gccatatgaa tgcaatgctt gtgggaaaag cttcagccgg     1500

agctctcatc tcatcacaca ccagaaaatt cacactggag agaagcctta tgagtgtaat     1560

gagtgttggc gaagctttgg tgaaaggtca gatctaatta aacatcagag aacccacaca     1620

ggggagaagc cctacgagtg tgtgcagtgt gggaaaggtt tcacccagag ctccaacctc     1680

atcacacatc aaagagttca cacgggagag aaaccttatg aatgtaccga atgtgagaag     1740

agtttcagca ggagctcagc tcttattaaa cataagagag ttcatacgga ctaagctgta     1800

attatgatgg ctgagaaatg attcatttga agatacaatt ttatttgata tcaatgaacg     1860

ccctcaagac tgagctgctt ttatcatact ctcctagttg tgggccacga tttaaaccat     1920

cagagatgac aagccatttg aaattctgac cctcagcttt gggaatgtta tctcctccaa     1980

aatggtgatt tttattcact caatgggtta cttcattaaa agcagcccca caagtaactg     2040

gaaatctgaa gaccagggga caaatgctgg tgaatgctta ggcctggaaa tggagtaaat     2100

ctttcaatgt tattttctcc catccttggc ccaaggaact atgctaagtg aaacgtggga     2160

ctgtaatagg gtggtaatgg ctgctttgga aaaaggcaac tagagactct gcctaaattg     2220

ccacacctat tcacacacca tagtagttgg gcacacacat cttcccttcc aaagggcttt     2280

ttccttgagt tgctcatgca tttgtatctt ttccatcttc ctgagggcaa gattttgcac     2340

gatgaaggca atgattgtaa cttttctcct tctcattgtt tctaattagc tcctttaaag     2400

cttgcatctt tgtgaaggct aactgaagat acggttggaa aggaaaaatg agacacaggt     2460

ttggggacca aggacccatc aatgatggtg actttagcag aagatgccca cagttattac     2520

tgccattaat cagatttatg aattttcttt ggggatcact atagggaata ttgtatagaa     2580

aatatcttca agaaaagata ggaccatcag tgacagttaa gtgtaaggag caagtggaat     2640

tgagtccttc agggaaggaa ccacagagtc ccttcccaag gaatgtaggt cgtttctgtg     2700

ttctttccct tctaatcttt aagatcaact cttcctatcc tgctaactct aagatttgat     2760

aagggccaca tcccagtgtt tatcttagct tgcatcaggg catgtgtatg tacagtaatg     2820

tgtattcctg tggtttttct aatagaaact gaatttacag agacttagca tgttcttggg     2880

tgatgtgagt catgtgacag aagtacagac ataactccaa tgtgagaaat gtcctttttt     2940

cattatggaa aataatttaa acactagtgc tttagtgtgc actctcctgt aaggtctgtc     3000

tttgtacaga gctaagcact tgtttgtatg tgtttgtcaa ttgtggaaga taatgaccag     3060

acaaataggt cgattgtcct attctcagaa tgaattatct tctatggtaa tgaagaactc     3120

tttggcttag tcagaaggaa ttaacgaacc tcggtaggaa tgtatttcca tcctcccacc     3180

ctacagatat aagaggttaa aataacagtt cgcccaattt aagcccagta gtgtcagttt     3240

tcctaatctc agtccaggta ggaattaaga aatatctcaa gtgttgatgc tatccaagca     3300

tgttggggtg gaagggaatt ggtgcccaga aaatgggact ggagtgagga atatcttttc     3360

ttttgagagt acccccagtt tatttctact gtgctttatt gctactgttc tttattgtga     3420

atgttgtaac attttaaaaa tgttttgcca tagcttttta ggacttggtg ttaaaggagc     3480

cagtggtctc tctgggtggg tactataatg agttattgtg acccacagct gtgtgggacc     3540

acatcacttg ttaataacac aacctttaaa gtaacccatc ttccaggggg gttccttcat     3600

gttgccactc ctttttaagg acaaactcag gcaaggagca tgtttttttg ttatttacaa     3660

aatctagcag actgtgggta tccatatttt aattgtcggg tgacacatgt tcttggtaac     3720

taaactcaaa tatgtctttt ctcatatatg ttgctgatgg ttttaataaa tgtcaaagtt     3780

ctcctgttgc ttctgtgagc cactatgggt atcagcttgg gagtggccat agatgaccgc     3840

atttccatga cctaactgta tttcaccccc ttttccttcc ctactgttct tgccccaccc     3900

caaccagttc ctgctgctgc ttttggcttc ttggaggtga agggcttaaa acaaggcttc     3960

taagcaccca gctatctcca tacatgaaca atctagctgg gaaacttaag ggacaagggc     4020

cacaccagct gtctcctctt tctgccaatt gttgcccgtt tgctgtgttg aactttgtat     4080

agaactcatg catcagactc ccttcactaa tgctttttgc atgccttctg ctcccaagtc     4140

cctggctgcc tctgcacatc ccgtgaacac tttgtgcctg ttttctatgg ttgtggagaa     4200

ttaatgaaca aatcaatatg tagaacagtt ttccttatgg tattggtcac agttatccta     4260

gtgtttgtat tattctaaca atattctata attaaaaata taatttttaa agtca          4315


<210>  2276
<211>  5768
<212>  DNA
<213>  homo sapiens

<400>  2276
aggcgccctc ccctcgccgg gggccgcgag ttgcatttgg taaaacccag ccccggaata       60

tatagatcgt tggagcgcaa tgaagtagcc tttggagaga agggagaggg cccgtcggac      120

agccacagcg gccagcgcag cggcagcggc ggcggcacca ccatcaccgc tcgcacccca      180

gccgcccggc ccgcgaccag gcagcggcgg ccgccggcgg gatcggagga ggcggcggag      240

cggcgaggag gaggagcagg agcgcgcagc cagcgggtcc acgcatctca gcacttccag      300

accaactccg gcaccttcca cacccctgcc cgggctgggg gctccgagag cggccgcgaa      360

gcgactccga tcctccctct gagccttgct cagctctgcc ccgcgcctcc cgggctccgg      420

tccgcgcggc ggggtccctg ctcctgcgcc ccgggcgcgc ttcccggaca ccccggtccc      480

cgcagccagg acaaagccat gaagccagcg ctgctggaag tgatgaggat gaacagaatc      540

tgccggatgg tgctggccac ttgcttggga tcctttatcc tggtcatctt ctatttccaa      600

agtatgttgc acccagtcat gcggaggaat ccctttggtg tggacatctg ctgccggaag      660

gggtcccgaa gccccctgca ggaactctac aacccaatcc agctggagct ctcaaacact      720

gctgtcctgc accagatgcg gcgggaccag gtgacagaca cgtgccgagc caacagcgcc      780

acaagccgta agcggagggt gctgaccccc aacgacctga agcacttggt ggtggatgag      840

gaccacgagc tcatctactg ctacgtgccc aaggtggcct gcaccaactg gaagcggctc      900

atgatggtcc tgaccgggcg ggggaagtac agcgacccca tggagatccc ggccaacgag      960

gcacacgtct ccgccaacct gaagaccctg aaccagtaca gcatcccaga aatcaaccac     1020

cgcttgaaaa gctacatgaa gttcctgttt gtccgggagc ccttcgagag gctagtgtcc     1080

gcctaccgca acaagttcac ccagaagtac aacatctcct tccacaagcg gtacggcacc     1140

aagatcatca aacgccagcg gaagaacgcc acccaggagg ccctgcgcaa aggggacgat     1200

gtcaaattcg aggagtttgt ggcctatctc atcgacccac acacccagcg ggaggagcct     1260

ttcaacgaac actggcaaac cgtctactca ctctgccatc cctgccacat ccactatgac     1320

ctcgtgggca agtacgagac actggaagag gattctaatt acgtcctgca gctggcagga     1380

gtgggcagct acctgaagtt ccccacctat gcaaagtcta cgagaactac tgatgaaatg     1440

accacagaat tcttccagaa catcagctca gagcaccaaa cgcagctgta cgaagtctac     1500

aaactcgatt ttttaatgtt caattactca gtgccaagct acctgaaatt ggaataaagg     1560

gggtggggag agggagagaa tcatgctttt taatttaaga tttttatttg tcaaaagaat     1620

tatatggata ttgggttatt ttgtaaatta atatttcttt ggggatgatg ctgcgagcag     1680

catagtgaga attatttaaa atccttcgta gggaaggaca gctgtctttg caggggaaat     1740

aggatgggtc gtccttgtct gtagaagtga atactgcaac actgtctcaa aggtttcttg     1800

tgttctggtg aattccatga attgtgcatt ccataaattc taattaatat tatttatagt     1860

tatttaaaca tggtctcatt atttcttttt gtggcagcaa aattctaaca tctttccaga     1920

agaaatctat gattcctgct ttgcttgcta cagctcattt gggggcatga atgttctcct     1980

tactaacctc tcatggagtc atgtgataac agccattgtc atgtgtatgg atgccaccat     2040

tcttgaattt ctgctagaaa taagtaggtt gctattgcac ttagagtcat ctttgcaagg     2100

gactcattcc aaaccaattc caatcgacct gaaagtccct tgcactaaag aaatgtgatt     2160

tttttttaac ccaaggagaa agttggttgt aacaattttt caccagaatt agcaatctga     2220

tagaataggc ttttttaaca ggaattttaa actggcggtg ccagttgcag tgaaggtgaa     2280

gtggctattg ctttatattc gacaaatatt tattgagcat ctactatata ctaggccctg     2340

aagatagagc gttgaacaaa cccaatagtc ttggccctca aaaagcttta tgtgacatag     2400

agcatccagc tcgacaatta gcaaacccct gatattattc atggacttga catgaggttt     2460

ggactattca tgagcaacag cagaaggtcc atgaccccta caaatttaca tttttctatg     2520

gcccatattt gaaaacctca cattcggagc aggccacttt atattcgtga gtgatcccaa     2580

gctcactgac caacagaaaa gatgctaaaa aaatgtgtcc tatcatgtgc ctgctccaac     2640

tgatgggtaa tgtctgcctt taagccccag aatggattct ccaggcacag tgtggaagag     2700

tgctgtggtt gattagcaat gtctgccttg ggtgaggaaa ggggaacact cctcaagtgc     2760

ctcctactgt catctccatt cagcctagca ccacatcccc atgtagaagt gttgtcttct     2820

actgcttgcc acgtacaagt gtgaaatgcc aaggtgagac tcgtacactt ggggatttgc     2880

aatggttttt acccctcatg aaggtcagag gtggactatt tgtacacata cacacatgca     2940

caccctctca cgtcctccag aggctgaaag actatcagca tcttggtaac tgccatgcat     3000

gagcagcaag gacagccttc cataatccat gccccatttc ctctggaagc ctggaaactt     3060

ttcatttcct gttccttgct aattaacatc taaacatgct tctcatttcc agccattgct     3120

gatgcttctc agttgaagtt tgagccacat ccctcttaca gctagtgaat gagttggtag     3180

cagctactgt atataataat aataatagtt ttaataatag gggagggtgg gatggggtgt     3240

gggtaagttt tgccttttgt tttgtttttg atgccgtata tagtgaaggg gtgaggatat     3300

tctaaacaaa caaaaattga ataatttatt cacagaaact attaagattg tattgtaaag     3360

ctcacagcaa gctcagtggg cagcagctgc aacatctcac cggggaaatt attttattta     3420

acgtgagtga gatgtgggcc ggagaaggta gctgaagcta tttataaaac gttgtgtacc     3480

ttcttccgag ctctctcccc tttgtgaagg gcgcagcaac tatacccttg atggatggag     3540

atttacgcaa tgtgttttac tgggtagagt gacagacctt ggctgtccct ggaattgaga     3600

atctggacct tatttccagg cagagaacac tgtcctcaga aatgggactt ctgataatga     3660

aacaggttgt ccaacatttt ctaatacgca ttctacagaa cacaggttcc aggaggcatc     3720

aggttggtgt gatgcagact aagggttttg tggtcaaata tccttaagaa acaaagttaa     3780

gtcagtttcc tttctgcaag gacttttcag ccttcaatgt gtgctgtgca tggtgaatcc     3840

ccaaaaataa tccttgagtc tgtagcattt cctgaactta catgaccagg atactctatt     3900

ttgcagatca ccccacagag ctagggttcc accgagtata ctttgcttag gttgacttag     3960

catatctgag gtcttcaagg ataaaaactg ccaccccaac acccttccat taaaaaaaaa     4020

atacaaaata gcaccacagt ctccatctgg tttatagcaa cagaggtact ttatttaatg     4080

aagcaatggt tctaatcctg gatactgcca cggactacaa ttctatccct cccagaggga     4140

gtggaggaag tcttgggtgg tgtggacaga aggaagagag gagagggtga gtggggtata     4200

gggcccaggg tggctcccta ctcctcaggc tcaaaaggat gctcagtggg aacagatgat     4260

ctcttgatga gtgcttcttc agtttcatag tttggaatcg ttcactgtgt gctttttggg     4320

gggttttcaa tggaaattca cgttgctttg catttctgtg tccgtctttg gtcagttgtg     4380

caagcctgct cactgtcatg tgaagatggc ctttcatctg gcttctctct cttaagtgag     4440

aaagattgtc cttcagggga catgacatca ataggtttct ggaatgaggg actctttctc     4500

cccgtgtttt gctttgtgtt cacattttct tttctaatgg cattgaaact ttaaaaaaaa     4560

tggattcaac tgtttttgca gaatgtagaa agtattctgt gtccttggtt aaagaaatcc     4620

acttgtgaag tgtgcctgga aaatgaaagt ttgtgttttt taaagaggaa tatttgaaac     4680

tgctttctat gcatgcttag ctggagaaaa gtacaggcag gcgtcccatc tcccagccac     4740

ttctcaaagg tgctgctgtg ttttaaagac caggtacagc cagggcagta tttgcaagga     4800

cattcctgct tactttatcc ctttggttgg aaagctctag atgattcccg cagctcctcc     4860

agaccccgcc tccctgccct ccccagctgg tctgggaaga ggtggtctgc tgacctgtgg     4920

tatctcagag gggacgttcc tcctcctccc tgtgcaccag gtgggctgca ccctcctgcc     4980

tattcaggat gtggatgcca caggagagca gcaggcagtg gaaacttcag ttgcactggt     5040

tctcctggtg gcaaaggcat gaagcacagg ggtcgattaa tccaggctac tagaaagctc     5100

cagagcaaag tgtgcgggtc ccacaaatgc ttggctggtg gggtctggat cagtgctgag     5160

atagagttgg cagaagaagc agaggcactc tgcttgcttt cctagccagt cctcccctac     5220

acacacacac acacacacac acacacacac acacaatctc agctgcgcca ttctgtgcaa     5280

tcccagtgac caaatccctt ccttgcccac ctctatgtca gcaggactga ccacatcact     5340

cccccgagtt cccaccacca gcatttcctc caaccttttt ccatcacaac cagttagaac     5400

cctacaggca acaaggcctt ctagaatccg cttaaccctt ggctgataac aggcaaattt     5460

cagtctgcta cactttgtta ggtccagaag gagctgccca tactactttc ttatgagcat     5520

gctcagtatg gcatatggac atgtaatgtc acatctttgt ggagtgtgat tttctttttt     5580

cacatatttg tatgcagtag agagcctgtt gtagaaaacg ctccctgtat cttgctgtac     5640

tgttaaagaa agctgaattc cacattgcca acaaaagcgt gaaaatgttc atgaaccttc     5700

ctccaggaaa agccattcaa gcctgattat ttttctaagt aacttcaatt aaattgaaga     5760

aaaaagaa                                                              5768


<210>  2277
<211>  1148
<212>  DNA
<213>  homo sapiens

<400>  2277
gcgccgagac ccgctcctgc agtattagtt cttgcagctg gtggtggcgg ctgaggcggc       60

atggatctca gcgagctgga gagagacaat acaggccgct gtcgcctgag ttcgcctgtg      120

cccgcggtgt gccgcaagga gccttgcgtc ctgggcgtcg atgaggcggg caggggcccc      180

gtgctgggcc ccatggtcta cgccatctgt tattgtcccc tgcctcgcct ggcagatctg      240

gaggcgctga aagtggcaga ctcaaagacc ctattggaga gcgagcggga aaggctgttt      300

gcgaaaatgg aggacacgga ctttgtcggc tgggcgctgg atgtgctgtc tccaaacctc      360

atctctacca gcatgcttgg gcgggtcaaa tacaacctga actccctgtc acatgataca      420

gccactgggc ttatacagta tgcattggac cagggcgtga acgtcaccca ggtattcgtg      480

gacaccgtag ggatgccaga gacataccag gcgcggctgc agcaaagttt tcccgggatt      540

gaggtgacgg tcaaggccaa agcagatgcc ctctacccgg tggttagtgc tgccagcatc      600

tgtgccaagg tggcccggga ccaggccgtg aagaaatggc agttcgtgga gaaactgcag      660

gacttggata ctgattatgg ctcaggctac cccaatgatc ccaagacaaa agcgtggttg      720

aaggagcacg tggagcctgt gttcggcttc ccccagtttg tccggttcag ctggcgcacg      780

gcccagacca tcctggagaa agaggcggaa gatgttatat gggaggactc agcatccgag      840

aatcaggagg gactcaggaa gatcacatcc tacttcctca atgaagggtc ccaagcccgt      900

ccccgttctt cccaccgata tttcctggaa cgcggcctgg agtcagcaac cagcctctag      960

cagctgcctc tacgcgctct acctgcttcc ccaacccaga cattaaaatt gtttaaggag     1020

aaccacacgt aggggatgta cttttgggac agaagcaagg tgggagtgtg ctctgcagcc     1080

gggtccagct acttcctttt ggaaccttaa atagaatggg tgttggttga ttaattttat     1140

ttaaaaaa                                                              1148


<210>  2278
<211>  3210
<212>  DNA
<213>  homo sapiens

<400>  2278
tttttctgtg cttgccttgg agaccgcgag gcggatcacg cccctagtcc agggtcggag       60

ggctgagggg gaactttgca gagagaaggg tttaaaggag gtcatggaaa cgggactggg      120

tgctccgcta tttaaagctt ggctgctgat ctcagtttgg gggcttggtg tggacccttc      180

cctacagatt gacgtcttaa cagagttaga acttggggag tccacgaccg gagtgcgtca      240

ggtcccgggg ctgcataatg ggacgaaagc ctttctcttt caagatactc ccagaagcat      300

aaaagcatcc actgctacag ctgaacagtt ttttcagaag ctgagaaata aacatgaatt      360

tactattttg gtgaccctaa aacagaccca cttaaattca ggagttattc tctcaattca      420

ccacttggat cacaggtacc tggaactgga aagtagtggc catcggaatg aagtcagact      480

gcattaccgc tcaggcagtc accgccctca cacagaagtg tttccttaca ttttggctga      540

tgacaagtgg cacaagctct ccttagccat cagtgcttcc catttgattt tacacattga      600

ctgcaataaa atttatgaaa gggtagtaga aaagccctcc acagacttgc ctctaggcac      660

aacattttgg ctaggacaga gaaataatgc gcatggatat tttaagggta taatgcaaga      720

tgtccaatta cttgtcatgc cccagggatt tattgctcag tgcccagatc ttaatcgcac      780

ctgtccaact tgcaatgact tccatggact tgtgcagaaa atcatggagc tacaggatat      840

tttagccaaa acatcagcca agctgtctcg agctgaacag cgaatgaata gattggatca      900

gtgctattgt gaaaggactt gcaccatgaa gggaaccacc taccgagaat ttgagtcctg      960

gatagacggc tgtaagaact gcacatgcct gaatggaacc atccagtgtg aaactctaat     1020

ctgcccaaat cctgactgcc cacttaagtc ggctcttgcg tatgtggatg gcaaatgctg     1080

taaggaatgc aaatcgatat gccaatttca aggacgaacc tactttgaag gagaaagaaa     1140

tacagtctat tcctcttctg gagtatgtgt tctctatgag tgcaaggacc agaccatgaa     1200

acttgttgag agttcaggct gtccagcttt ggattgtcca gagtctcatc agataacctt     1260

gtctcacagc tgttgcaaag tttgtaaagg ttatgacttt tgttctgaaa ggcataactg     1320

catggagaat tccatctgca gaaatctgaa tgacagggct gtttgtagct gtcgagatgg     1380

ttttagggct cttcgagagg ataatgccta ctgtgaagac atcgatgagt gtgctgaagg     1440

gcgccattac tgtcgtgaaa atacaatgtg tgtcaacacc ccgggttctt ttatgtgcat     1500

ctgcaaaact ggatacatca gaattgatga ttattcatgt acagaacatg atgagtgtat     1560

cacaaatcag cacaactgtg atgaaaatgc tttatgcttc aacactgttg gaggacacaa     1620

ctgtgtttgc aagccgggct atacagggaa tggaacgaca tgcaaagcat tttgcaaaga     1680

tggctgtagg aatggaggag cctgtattgc cgctaatgtg tgtgcctgcc cacaaggctt     1740

cactggaccc agctgtgaaa cggacattga tgaatgctct gatggttttg ttcaatgtga     1800

cagtcgtgct aattgcatta acctgcctgg atggtaccac tgtgagtgca gagatggcta     1860

ccatgacaat gggatgtttt caccaagtgg agaatcgtgt gaagatattg atgagtgtgg     1920

gaccgggagg cacagctgtg ccaatgatac catttgcttc aatttggatg gcggatatga     1980

ttgtcgatgt cctcatggaa agaattgcac aggggactgc atccatgatg gaaaagttaa     2040

gcacaatggt cagatttggg tgttggaaaa tgacaggtgc tctgtgtgct catgtcagaa     2100

tggattcgtt atgtgtcgac ggatggtctg tgactgtgag aatcccacag ttgatctttt     2160

ttgctgccct gaatgtgacc caaggcttag tagtcagtgc ctccatcaaa atggggaaac     2220

tttgtataac agtggtgaca cctgggtcca gaattgtcaa cagtgccgct gcttgcaagg     2280

ggaagttgat tgttggcccc tgccttgccc agatgtggag tgtgaattca gcattctccc     2340

agagaatgag tgctgcccgc gctgtgtcac agacccttgc caggctgaca ccatccgcaa     2400

tgacatcacc aagacttgcc tggacgaaat gaatgtggtt cgcttcaccg ggtcctcttg     2460

gatcaaacat ggcactgagt gtactctctg ccagtgcaag aatggccaca tctgttgctc     2520

agtggatcca cagtgccttc aggaactgtg aagttaactg tctcatggga gatttctgtt     2580

aaaagaatgt tctttcatta aaagaccaaa aagaagttaa aacttaaatt gggtgatttg     2640

tgggcagcta aatgcagctt tgttaatagc tgagtgaact ttcaattatg aaatttgtgg     2700

agcttgacaa aatcacaaaa ggaaaattac tggggcaaaa ttagacctca agtctgcctc     2760

tactgtgtct cacatcacca tgtagaagaa tgggcgtaca gtatataccg tgacatcctg     2820

aaccctggat agaaagcctg agcccattgg atctgtgaaa gcctctagct tcactggtgc     2880

agaaaatttt cctctagatc agaatcttca agaatcagtt aggttcctca ctgcaagaaa     2940

taaaatgtca ggcagtgaat gaattatatt ttcagaagta aagcaaagaa gctataacat     3000

gttatgtaca gtacactctg aaaagaaatc tgaaacaagt tattgtaatg ataaaaataa     3060

tgcacaggca tggttactta atattttcta acaggaaaag tcatccctat ttccttgttt     3120

tactgcactt aatattattt ggttgaattt gttcagtata agctcgttct tgtgcaaaat     3180

taaataaata tttctcttac cttataacac                                      3210


<210>  2279
<211>  901
<212>  DNA
<213>  homo sapiens

<400>  2279
ccaggagctc agaccgctct ttgagactct cccgaaggag aatgggaggg taggggcgct       60

gccagactcc ttccctggtg ggcctagatg aagacgctca aggaccctcg tgacttggcc      120

gagacagggg aagggagaag ttgagtcggg caaggaagag atgctaaagc ctggggaatt      180

aagaacatgc cagaatcatc ccgagggagt ctggaattag ggagggtgag gactcgctag      240

gatcgtcctg tggatctggc tacagcagga gctgatgacc ctcatgatgt ctggcgataa      300

agggatttct gccttccctg aatcagacaa ccttttcaaa tgggtaggga ccatccatgg      360

agcagctgga acagtatatg aagacctgag gtataagctc tcgctagagt tccccagtgg      420

ctacccttac aatgcgccca cagtgaagtt cctcacgccc tgctatcacc ccaacgtgga      480

cacccagggt aacatatgcc tggacatcct gaaggaaaag tggtctgccc tgtatgatgt      540

caggaccatt ctgctctcca tccagagcct tctaggagaa cccaacattg atagtccctt      600

gaacacacat gctgccgagc tctggaaaaa ccccacagct tttaagaagt acctgcaaga      660

aacctactca aagcaggtca ccagccagga gccctgaccc aggctgccca gcctgtcctt      720

gtgtcgtctt tttaattttt ccttagatgg tctgtccttt ttgtgatttc tgtataggac      780

tctttatctt gagctgtggt atttttgttt tgtttttgtc ttttaaatta agcctcggtt      840

gagcccttgt atattaaata aatgcatttt tgtccttttt tagacaaaaa aaaaaaaaaa      900

a                                                                      901


<210>  2280
<211>  8554
<212>  DNA
<213>  homo sapiens

<400>  2280
aacatttaca acaaagttga ttctgtgtag ggttggaggc tagacagttc cacaaatttt       60

tagtcacatt ttccatgtca gttaaatcta gggagttcaa gactactgga aaaattagtc      120

tcattactaa aagaaactta gagaacgagg gaggtaccag agtctaggag gtacctctgg      180

gttgcagaag taattgtaaa ataccagacc tgttcttttt actaaaagct agtttcacta      240

tcttctggtc tgaaatactg aggcaaatac tcaagactta ttttcttcct aatcttgctg      300

gtgaaacaga agttactaga aagaaaggaa gaaaaaactt gatttggtga ctgcaggaag      360

caacacgttg ctgcttttat tctacagata atgatttatg aggaatccaa gatgaatttg      420

gagcaggaga ggccgtttgt ctgcagtgcc ccaggctgct cccagcgctt cccaacagag      480

gaccatctga tgattcatag gcacaaacat gaaatgactt tgaagtttcc ttcaataaaa      540

acagacaata tgttatcaga tcaaactccg accccaacga gattcctgaa gaactgcgag      600

gaggtgggcc tcttcagcga gctggactgc tccctggagc acgagttcag gaaggctcag      660

gaagaggaga gcagcaagcg gaatatctcg atgcataatg cagttggtgg ggccatgacg      720

gggcccggaa ctcaccagct tagcagcgct cggctgccca accatgacac caacgttgtg      780

attcagcaag ccatgccgtc gcctcagtcc agctctgtca tcactcaggc accttccacc      840

aaccgccaga tcgggcctgt cccaggctct ctatcttctc tgctacatct ccacaacaga      900

cagagacagc ccatgccagc ctccatgcct gggaccctgc ccaaccctac aatgccagga      960

tcttccgccg tcttgatgcc aatggagcga caaatgtcag tgaactccag catcatgggg     1020

atgcaaggtc caaatctcag caacccctgt gcttctcccc aggtccagcc aatgcattca     1080

gaagccaaaa tgaggttgaa ggctgcattg actcaccacc ctgctgccat gtcaaatggg     1140

aacatgaaca ccatgggaca catgatggag atgatgggct cccggcagga ccagacgcca     1200

caccatcaca tgcactcgca cccgcatcag caccagacac tgccacccca tcacccttac     1260

ccacaccagc accagcaccc agcacaccat cctcaccctc aaccccatca ccagcagaac     1320

catccacatc accactccca ttcccacctt catgcacacc cagcacatca ccagacctcg     1380

ccacatccgc ccctgcacac cggcaaccaa gcacaggttt caccagcaac acaacagatg     1440

cagccaaccc agacaataca gccaccccag cccacagggg ggcgccggcg aagggtggta     1500

gacgaggatc cggacgagag gcggcggaaa tttctggaac ggaaccgggc agctgccacc     1560

cgctgcagac agaagaggaa ggtctgggtg atgtcattgg aaaagaaagc agaagaactc     1620

acccagacaa acatgcagct tcagaatgaa gtgtctatgt tgaaaaatga ggtggcccag     1680

ctgaaacagt tgttgttaac acataaagac tgcccaataa cagccatgca gaaagaatca     1740

caaggatatc taagtccaga gagtagccct cctgctagtc ctgtcccagc ttgctcccag     1800

caacaagtca tccagcataa taccatcact acttcctcat cggtcagcga ggtggtagga     1860

agctccaccc tcagccagct caccactcac agaacagacc tgaatccgat tctttaaaat     1920

gcaccatcag acctggcctc caagaagagc tgtagcgtac catgcgtcct ttcttttaag     1980

ggcattttta gaattaactc agacctggaa gactcctcag ttcttcaaag actggctttc     2040

atttttatag ttattatgga aatgttgtct tttatactta gttatataag aaaaaaggga     2100

gttatgcaat taatatctat cagcttggga aacgctttgg tgcttttctc cagttttctg     2160

gtaccagtta cttgtttata aactgaacct tttctgtata tagccatggt ttcattctta     2220

tcagtccaac cctttgcctg aaacattgaa tcttgttaaa ccacagcttt tagctaaaat     2280

gaggtatacc tagatgtcaa gtaagacaga tccaaggtaa ctgggtagga aatcttttga     2340

catcttaact catgttgagt ttgtgctgtg gtgtcaccag aattccagat aaacacacag     2400

cctttcccat accttttttt ttcttactat aaaatattat aagatccatt gatgtccaaa     2460

taataccacc aagcatctct tcacctctcc tcctcttggt ccacttgcta atgcccagtt     2520

ttcttctcca tttccacttt ttcttaggct ccctatttac tattcatttt gacttccttc     2580

tgttttattt ttttcccttt agcattgcat gtgaataaga aaataatgtt taaagaaaaa     2640

aaaaaaaaag caaacctcca aaacgtggac ctaaccattg cttcacttac acttcaccca     2700

cagctggagt tcattcaact cttgcttttc acaaaatagt aaccaggaga tgtttaatgt     2760

gcctgattta atgtttttaa taatcacagc aaatgaaagg tggtttagtt ataagtgaag     2820

catggttgaa taccagctgg ggagacacta gggaagggag ctttgtaagc cttgattgcg     2880

aaagtccaaa ttttgatgtg gggctataac atgacaccct tggattgcga ctggttttat     2940

acggcctgcc tataacgttg aaaatccatg tactacataa taattcagaa gggctctatt     3000

cactacacag attacattgt tcaatcatca gctgctaata gcctaagatt tatttttttt     3060

tttttcttaa gcctatggaa ccggctttgc tgttctgggg ggtgaaaata gactaactac     3120

tggagaaaca aagagagaaa gaaaacccag tgtttccata ggggcacttt tagccttccc     3180

acaacagtta agcactcttt gactgctgaa ggaaccccat ggatgaggtg caggctactt     3240

cactcttttt ttttcttttt tgagacagag tctcacctat tgcccagact gaagtgcagt     3300

ggtgcgatca tggatcactg cagcagcatc ctccgagttc aagctatcct tccacctccg     3360

cctcctgagt agctgggacc acaggttcac ataaccatgc ctggctaatt tatttttact     3420

tttattttaa aataaaagat gaggtctgtc ttatgttgcc caggctggtc tcaaactatc     3480

ctacttcttc ctcccaaagt gttgggatta taggtgtgag ccactgcacc cagcctactt     3540

cactcttctg aattattctg atttattttc aacaactttt gtgaacttgc ccgtgataca     3600

aagcagatag tccctgaacc acagtcgtgc ctccttgaaa caagccattc tactgtgcta     3660

atgttttaat atcacatctc acaaataaca ggggtgaatg tttctctcta gcaatctagg     3720

caggtgctgg tgtttcatct ccatttgaat gcttgacctc ttaatgtgtg tgtgtgtgtg     3780

tgtgtgtgtg tgtgtgttca tgggttttaa aagaacagta ttttacaaaa ggtgtagctt     3840

ttataagagt gcagaaaagg gaaggatgtg tttttttctc tcactatagt ataagaatct     3900

attttggaga aaaaaagaaa atatgagggt ctcgaagcat gatttttata taactagttt     3960

cagttttatc taataactta ctttttaaat caatatttat caacaatctt tccttgtatg     4020

cagtgctttc aaaagatggt tttgagtgtc cagtgaaact tatgacttgg atatatggtt     4080

gaagaatcaa aacaaaagca aaaaaaaaaa gcaaaaaaag aaaagagaaa aaaagaaaaa     4140

atgcaaatgg aataattttc tattatattt tagacaaaca tatcattttc gagtatttta     4200

aatactgaat tcatagttgt tgttttttaa attccaacag taacagctga atggtttaat     4260

ctgactggct tcctaagaaa tgtttaagac tcagctttaa aaagaagtta acattcatat     4320

ctctgttttg aaatcaaaaa tcatatttca aaattctttc ctaggaccat ctatgtgtct     4380

cccctcccct ccacaaaaag gagaaagagt gcattaaaat gtttagttgg gttttttaat     4440

ttttaatttt tatgttatgt tttgctttgt tttaagtaaa caaaaatttt tctttcttta     4500

ctgcatgcat agcacttaat aaaatggatt tttaaaaaat ccactagtaa tatcagaatg     4560

tccagggagt gactgtcact acaatgatgg tttagtttac ttctgttcca ccttttgatt     4620

gaaatattta gttgttaggc tgaaagcctc ggcagttaag aacttgcctg agttttcttc     4680

gttcagcaac ttgacagttt gactgatgtg cattatatat agctcaatta tgtctgtttt     4740

ttatgctaag taggaaaacc aaccacacac attagcaaac cggcctcaac atataattag     4800

aataaactgt cttcttgttc tactcagggc ctttaggtgt gttcattcac ggtatggaaa     4860

tacagtaaat gaaagattcc aactagttgt cagtgcttct tgaaattcca aacagaaaga     4920

tacattggtc aaatccaaca cttggcttat caatattaag tcttttacct aaaggcccag     4980

ccgtcaccag acaacagaat aatcaatctg cctgaaaatc cctcctcctt gtcctacact     5040

ttttgcctgt ttgggagaat atctttgtac tccattctcc tccctcagcc agttactggg     5100

tcacccatcc atgtgttcat gaatcaatca tcacggcctg cagagcacct gtcctaagga     5160

gggaaaatcc tgtcacactg cctctcccca ttcgtgtgtg gttttcttga tcggtgagat     5220

ctgtctctga agtcactgcc agcctccctg ggaacgtcta tagtgcctcc cctgccttat     5280

gtgatgggag ttaacaactc agataagtac acctgagagc atttctatca ggtaaactgt     5340

cacttaaatg gaggtgtcca catcttaatt gtttctcctt gacacatttc tcaatccacg     5400

aagccaggag aggtagagtg aaaatcccag ccatggatga atgtactaat ttgaaagcca     5460

agtgttaagt cggatgtttt cccgttacac tactactcag ccctctcctg cggccacatc     5520

aacggatgca agtcacagtc ttaacacagc ctgtgggaga caagcagttt gtgtgctcac     5580

agtatatatt atagtaatta gggtgactta gagcaaatac tcttcagatc ctatgtagtc     5640

agtgaaacaa aatggagagc gtattctgat agaaggacgt cgacggtgaa tgttctggtg     5700

gttgttgcct gttaagtaaa ctttagtgtg taagttgagt ttgtcattaa aatcataaac     5760

cagctgcggt aacagacaag cctttggctg gggagtttta agcctcggta actgctataa     5820

aactagccat ccagttagga tagaatgtgt ttctttctgg ttaaaaaaag gaaaaaccat     5880

ctaagaaaat atatatgtat gtatgtgtgt atacagtgga attcaaagga ccaaagcaaa     5940

atttgaacag gaatctatta atttagaatt ttataagata tttattaata aatgttattt     6000

ttaaacattc catttgaaca gtattctgta ggatctactt gtttttaaag tgttagtcca     6060

taataaacta ctatagttat gtgtattttc atttttcagg gtttcaaatg gctattctcc     6120

atcatttggt ggaaatgttt gcttagatct ctgtgcatag acatttcaag gatttttatt     6180

gctctgtgag ttatttttta atcaacattc tgaacagttt tttttaaaca tttatttctg     6240

tgtgttcatt tttaaagtaa gctctttcat ttaggaagca gagttcagct aaagggaatc     6300

agtaactcta actggaacag ctttcttgta gaagtgtaaa aacagcttca tctctgcctc     6360

tctccacccc accccaattt cctagaaagc cttgcactat tcagctccct tagtgctttt     6420

tgtcccttcc cgaacaatat gcagtagctt taagccattc aagctccatt atgcagtata     6480

tctgagaagg gaaaggaaac aacccattta aatttgaata aaaccgtgcc tatgcgaaca     6540

gtagcaattt agaatctctt ttctgctttt aaaataattt atatttaaaa attgcacttt     6600

agctttttga tccctttgta tttctcttat tctctttcta acctcttctc tgtcctcaaa     6660

cttgcctttg ctctccttta caataccccc cacccctcct ccaaggctct gagcggcatc     6720

atttaaaata ctttacagat atttgcacca ggtacattta tgtgcgtcca ttggtagcac     6780

agctgagacc tgtgtctcac atcagcctag gtgaagccta ctacaagaat gccaaggaga     6840

agagccagta cactatatgg tttatactct ttatcccttt attcatagca tgttttttaa     6900

aaatgttata ttatgcaaca gatgtgaggc agcagctaag ctatacttaa gaattttctc     6960

tcaccttcca aaccaaagtg tcctgaataa gccaggagac ttattctttt gtgcaccctg     7020

gtgcacatct gactgttgtc ctagccatag actctctgag gccactgaaa gaacagtggc     7080

cctatcgatt tcattcctag gtctcaaaaa tacaatgttg ccttgtaaca taattaggga     7140

cagcacctct atttcacaat tataatctaa ggtaggataa gacgacacag cagcaataaa     7200

cttacaagta aaattcaata ccaaaacaaa cacaaagaaa tttaaaaaac aaaaaaccta     7260

gctcatcatg ttgtgaaaat gaaaaagtga atgtccattc aaaatatttt actatttctt     7320

gtggagtttt tcagtgatgt aatgcttgta gccaaattgc ttaaagagtg tttatatatt     7380

tttttcctta taaattgtct attttttaaa aaagctattt aaccacagct gaagtggggg     7440

gtaaggccaa attgccaaca cttgttaaaa gattaatact cttaagtggc actctgatac     7500

ctttccaact tgtcatcaga aaggaatcaa taattaccaa ctgttgtatt tagaccaact     7560

tacaatatct agctcattag aagccaggat ctagaaagct ccttctaagc catttaagat     7620

attcttacat tgagcttcat attatagaac tttataggat tggatatttt acaatagaat     7680

aatttagcct caggactgag aatgtggaag ctgaataaat tagctttaaa tacatcatta     7740

aaatcttatg cacaataagc tcattagatt ctagttttct cctttagaat accaatgcca     7800

cagacactac aggagataat gaaaggtatc agttgtgttg agtggaggga gtttaagaga     7860

aaggaccctt cccaaccagc agccagtaga aaatacaacc tactcacctt tttcccttct     7920

aagttctgct aaatcacatc tgcctcatag agaaaggaat gttgcctttg agaactgtct     7980

tggagaacag ataagcttga aatgttctct ctagagagga catagggttt gggatcctct     8040

gaaaaggccc agaaaaatag ctcagttcaa atacaatgtt ctaggacaat tggaatataa     8100

atattgtcca aaaatataat taaaagaaaa aagtttagca ctgtgtaaag taagtgttaa     8160

ctgaggaagt cccaaaaagg tgctgtcact ttaagttctg gacttggggt tctttgtatt     8220

tgtaaacagc aaagcatttg tgtttgtttg tctatttgta aagcaaccac cttccttatt     8280

ggaaggagaa aaaaaggggt acatacatgt aaatacttgc tgcagcattt aatatgttta     8340

attttgtgtt aagctttttg ttgcatcgtg aacacattta ttgttaccaa tggacaatga     8400

gttcattaag actgttcaac taggtcagat ttttacatct ctttctagca agaagagaca     8460

agattttgtg catttgtaca aatgttaata tcactgcaat tccaatataa taaagcactc     8520

aaatgcaaat aaaaaaaaaa aaaaaaaaaa aaaa                                 8554


<210>  2281
<211>  8210
<212>  DNA
<213>  homo sapiens

<400>  2281
gatctgatga atccaaggag tggagcaaga ggcagatttt ggacacggtt atgagaatga       60

cagaaactgc ctaaagcatt tatgctctgg cattcgtccc tgtttctgga ggtccagtaa      120

gcgcttccca acagaggacc atctgatgat tcataggcac aaacatgaaa tgactttgaa      180

gtttccttca ataaaaacag acaatatgtt atcagatcaa actccgaccc caacgagatt      240

cctgaagaac tgcgaggagg tgggcctctt cagcgagctg gactgctccc tggagcacga      300

gttcaggaag gctcaggaag aggagagcag caagcggaat atctcgatgc ataatgcagt      360

tggtggggcc atgacggggc ccggaactca ccagcttagc agcgctcggc tgcccaacca      420

tgacaccaac gttgtgattc agcaagccat gccgtcgcct cagtccagct ctgtcatcac      480

tcaggcacct tccaccaacc gccagatcgg gcctgtccca ggctctctat cttctctgct      540

acatctccac aacagacaga gacagcccat gccagcctcc atgcctggga ccctgcccaa      600

ccctacaatg ccaggatctt ccgccgtctt gatgccaatg gagcgacaaa tgtcagtgaa      660

ctccagcatc atggggatgc aaggtccaaa tctcagcaac ccctgtgctt ctccccaggt      720

ccagccaatg cattcagaag ccaaaatgag gttgaaggct gcattgactc accaccctgc      780

tgccatgtca aatgggaaca tgaacaccat gggacacatg atggagatga tgggctcccg      840

gcaggaccag acgccacacc atcacatgca ctcgcacccg catcagcacc agacactgcc      900

accccatcac ccttacccac accagcacca gcacccagca caccatcctc accctcaacc      960

ccatcaccag cagaaccatc cacatcacca ctcccattcc caccttcatg cacacccagc     1020

acatcaccag acctcgccac atccgcccct gcacaccggc aaccaagcac aggtttcacc     1080

agcaacacaa cagatgcagc caacccagac aatacagcca ccccagccca caggggggcg     1140

ccggcgaagg gtggtagacg aggatccgga cgagaggcgg cggaaatttc tggaacggaa     1200

ccgggcagct gccacccgct gcagacagaa gaggaaggtc tgggtgatgt cattggaaaa     1260

gaaagcagaa gaactcaccc agacaaacat gcagcttcag aatgaagtgt ctatgttgaa     1320

aaatgaggtg gcccagctga aacagttgtt gttaacacat aaagactgcc caataacagc     1380

catgcagaaa gaatcacaag gatatctaag tccagagagt agccctcctg ctagtcctgt     1440

cccagcttgc tcccagcaac aagtcatcca gcataatacc atcactactt cctcatcggt     1500

cagcgaggtg gtaggaagct ccaccctcag ccagctcacc actcacagaa cagacctgaa     1560

tccgattctt taaaatgcac catcagacct ggcctccaag aagagctgta gcgtaccatg     1620

cgtcctttct tttaagggca tttttagaat taactcagac ctggaagact cctcagttct     1680

tcaaagactg gctttcattt ttatagttat tatggaaatg ttgtctttta tacttagtta     1740

tataagaaaa aagggagtta tgcaattaat atctatcagc ttgggaaacg ctttggtgct     1800

tttctccagt tttctggtac cagttacttg tttataaact gaaccttttc tgtatatagc     1860

catggtttca ttcttatcag tccaaccctt tgcctgaaac attgaatctt gttaaaccac     1920

agcttttagc taaaatgagg tatacctaga tgtcaagtaa gacagatcca aggtaactgg     1980

gtaggaaatc ttttgacatc ttaactcatg ttgagtttgt gctgtggtgt caccagaatt     2040

ccagataaac acacagcctt tcccatacct ttttttttct tactataaaa tattataaga     2100

tccattgatg tccaaataat accaccaagc atctcttcac ctctcctcct cttggtccac     2160

ttgctaatgc ccagttttct tctccatttc cactttttct taggctccct atttactatt     2220

cattttgact tccttctgtt ttattttttt ccctttagca ttgcatgtga ataagaaaat     2280

aatgtttaaa gaaaaaaaaa aaaaagcaaa cctccaaaac gtggacctaa ccattgcttc     2340

acttacactt cacccacagc tggagttcat tcaactcttg cttttcacaa aatagtaacc     2400

aggagatgtt taatgtgcct gatttaatgt ttttaataat cacagcaaat gaaaggtggt     2460

ttagttataa gtgaagcatg gttgaatacc agctggggag acactaggga agggagcttt     2520

gtaagccttg attgcgaaag tccaaatttt gatgtggggc tataacatga cacccttgga     2580

ttgcgactgg ttttatacgg cctgcctata acgttgaaaa tccatgtact acataataat     2640

tcagaagggc tctattcact acacagatta cattgttcaa tcatcagctg ctaatagcct     2700

aagatttatt tttttttttt tcttaagcct atggaaccgg ctttgctgtt ctggggggtg     2760

aaaatagact aactactgga gaaacaaaga gagaaagaaa acccagtgtt tccatagggg     2820

cacttttagc cttcccacaa cagttaagca ctctttgact gctgaaggaa ccccatggat     2880

gaggtgcagg ctacttcact cttttttttt cttttttgag acagagtctc acctattgcc     2940

cagactgaag tgcagtggtg cgatcatgga tcactgcagc agcatcctcc gagttcaagc     3000

tatccttcca cctccgcctc ctgagtagct gggaccacag gttcacataa ccatgcctgg     3060

ctaatttatt tttactttta ttttaaaata aaagatgagg tctgtcttat gttgcccagg     3120

ctggtctcaa actatcctac ttcttcctcc caaagtgttg ggattatagg tgtgagccac     3180

tgcacccagc ctacttcact cttctgaatt attctgattt attttcaaca acttttgtga     3240

acttgcccgt gatacaaagc agatagtccc tgaaccacag tcgtgcctcc ttgaaacaag     3300

ccattctact gtgctaatgt tttaatatca catctcacaa ataacagggg tgaatgtttc     3360

tctctagcaa tctaggcagg tgctggtgtt tcatctccat ttgaatgctt gacctcttaa     3420

tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgttcatggg ttttaaaaga acagtatttt     3480

acaaaaggtg tagcttttat aagagtgcag aaaagggaag gatgtgtttt tttctctcac     3540

tatagtataa gaatctattt tggagaaaaa aagaaaatat gagggtctcg aagcatgatt     3600

tttatataac tagtttcagt tttatctaat aacttacttt ttaaatcaat atttatcaac     3660

aatctttcct tgtatgcagt gctttcaaaa gatggttttg agtgtccagt gaaacttatg     3720

acttggatat atggttgaag aatcaaaaca aaagcaaaaa aaaaaagcaa aaaaagaaaa     3780

gagaaaaaaa gaaaaaatgc aaatggaata attttctatt atattttaga caaacatatc     3840

attttcgagt attttaaata ctgaattcat agttgttgtt ttttaaattc caacagtaac     3900

agctgaatgg tttaatctga ctggcttcct aagaaatgtt taagactcag ctttaaaaag     3960

aagttaacat tcatatctct gttttgaaat caaaaatcat atttcaaaat tctttcctag     4020

gaccatctat gtgtctcccc tcccctccac aaaaaggaga aagagtgcat taaaatgttt     4080

agttgggttt tttaattttt aatttttatg ttatgttttg ctttgtttta agtaaacaaa     4140

aatttttctt tctttactgc atgcatagca cttaataaaa tggattttta aaaaatccac     4200

tagtaatatc agaatgtcca gggagtgact gtcactacaa tgatggttta gtttacttct     4260

gttccacctt ttgattgaaa tatttagttg ttaggctgaa agcctcggca gttaagaact     4320

tgcctgagtt ttcttcgttc agcaacttga cagtttgact gatgtgcatt atatatagct     4380

caattatgtc tgttttttat gctaagtagg aaaaccaacc acacacatta gcaaaccggc     4440

ctcaacatat aattagaata aactgtcttc ttgttctact cagggccttt aggtgtgttc     4500

attcacggta tggaaataca gtaaatgaaa gattccaact agttgtcagt gcttcttgaa     4560

attccaaaca gaaagataca ttggtcaaat ccaacacttg gcttatcaat attaagtctt     4620

ttacctaaag gcccagccgt caccagacaa cagaataatc aatctgcctg aaaatccctc     4680

ctccttgtcc tacacttttt gcctgtttgg gagaatatct ttgtactcca ttctcctccc     4740

tcagccagtt actgggtcac ccatccatgt gttcatgaat caatcatcac ggcctgcaga     4800

gcacctgtcc taaggaggga aaatcctgtc acactgcctc tccccattcg tgtgtggttt     4860

tcttgatcgg tgagatctgt ctctgaagtc actgccagcc tccctgggaa cgtctatagt     4920

gcctcccctg ccttatgtga tgggagttaa caactcagat aagtacacct gagagcattt     4980

ctatcaggta aactgtcact taaatggagg tgtccacatc ttaattgttt ctccttgaca     5040

catttctcaa tccacgaagc caggagaggt agagtgaaaa tcccagccat ggatgaatgt     5100

actaatttga aagccaagtg ttaagtcgga tgttttcccg ttacactact actcagccct     5160

ctcctgcggc cacatcaacg gatgcaagtc acagtcttaa cacagcctgt gggagacaag     5220

cagtttgtgt gctcacagta tatattatag taattagggt gacttagagc aaatactctt     5280

cagatcctat gtagtcagtg aaacaaaatg gagagcgtat tctgatagaa ggacgtcgac     5340

ggtgaatgtt ctggtggttg ttgcctgtta agtaaacttt agtgtgtaag ttgagtttgt     5400

cattaaaatc ataaaccagc tgcggtaaca gacaagcctt tggctgggga gttttaagcc     5460

tcggtaactg ctataaaact agccatccag ttaggataga atgtgtttct ttctggttaa     5520

aaaaaggaaa aaccatctaa gaaaatatat atgtatgtat gtgtgtatac agtggaattc     5580

aaaggaccaa agcaaaattt gaacaggaat ctattaattt agaattttat aagatattta     5640

ttaataaatg ttatttttaa acattccatt tgaacagtat tctgtaggat ctacttgttt     5700

ttaaagtgtt agtccataat aaactactat agttatgtgt attttcattt ttcagggttt     5760

caaatggcta ttctccatca tttggtggaa atgtttgctt agatctctgt gcatagacat     5820

ttcaaggatt tttattgctc tgtgagttat tttttaatca acattctgaa cagttttttt     5880

taaacattta tttctgtgtg ttcattttta aagtaagctc tttcatttag gaagcagagt     5940

tcagctaaag ggaatcagta actctaactg gaacagcttt cttgtagaag tgtaaaaaca     6000

gcttcatctc tgcctctctc caccccaccc caatttccta gaaagccttg cactattcag     6060

ctcccttagt gctttttgtc ccttcccgaa caatatgcag tagctttaag ccattcaagc     6120

tccattatgc agtatatctg agaagggaaa ggaaacaacc catttaaatt tgaataaaac     6180

cgtgcctatg cgaacagtag caatttagaa tctcttttct gcttttaaaa taatttatat     6240

ttaaaaattg cactttagct ttttgatccc tttgtatttc tcttattctc tttctaacct     6300

cttctctgtc ctcaaacttg cctttgctct cctttacaat accccccacc cctcctccaa     6360

ggctctgagc ggcatcattt aaaatacttt acagatattt gcaccaggta catttatgtg     6420

cgtccattgg tagcacagct gagacctgtg tctcacatca gcctaggtga agcctactac     6480

aagaatgcca aggagaagag ccagtacact atatggttta tactctttat ccctttattc     6540

atagcatgtt ttttaaaaat gttatattat gcaacagatg tgaggcagca gctaagctat     6600

acttaagaat tttctctcac cttccaaacc aaagtgtcct gaataagcca ggagacttat     6660

tcttttgtgc accctggtgc acatctgact gttgtcctag ccatagactc tctgaggcca     6720

ctgaaagaac agtggcccta tcgatttcat tcctaggtct caaaaataca atgttgcctt     6780

gtaacataat tagggacagc acctctattt cacaattata atctaaggta ggataagacg     6840

acacagcagc aataaactta caagtaaaat tcaataccaa aacaaacaca aagaaattta     6900

aaaaacaaaa aacctagctc atcatgttgt gaaaatgaaa aagtgaatgt ccattcaaaa     6960

tattttacta tttcttgtgg agtttttcag tgatgtaatg cttgtagcca aattgcttaa     7020

agagtgttta tatatttttt tccttataaa ttgtctattt tttaaaaaag ctatttaacc     7080

acagctgaag tggggggtaa ggccaaattg ccaacacttg ttaaaagatt aatactctta     7140

agtggcactc tgataccttt ccaacttgtc atcagaaagg aatcaataat taccaactgt     7200

tgtatttaga ccaacttaca atatctagct cattagaagc caggatctag aaagctcctt     7260

ctaagccatt taagatattc ttacattgag cttcatatta tagaacttta taggattgga     7320

tattttacaa tagaataatt tagcctcagg actgagaatg tggaagctga ataaattagc     7380

tttaaataca tcattaaaat cttatgcaca ataagctcat tagattctag ttttctcctt     7440

tagaatacca atgccacaga cactacagga gataatgaaa ggtatcagtt gtgttgagtg     7500

gagggagttt aagagaaagg acccttccca accagcagcc agtagaaaat acaacctact     7560

cacctttttc ccttctaagt tctgctaaat cacatctgcc tcatagagaa aggaatgttg     7620

cctttgagaa ctgtcttgga gaacagataa gcttgaaatg ttctctctag agaggacata     7680

gggtttggga tcctctgaaa aggcccagaa aaatagctca gttcaaatac aatgttctag     7740

gacaattgga atataaatat tgtccaaaaa tataattaaa agaaaaaagt ttagcactgt     7800

gtaaagtaag tgttaactga ggaagtccca aaaaggtgct gtcactttaa gttctggact     7860

tggggttctt tgtatttgta aacagcaaag catttgtgtt tgtttgtcta tttgtaaagc     7920

aaccaccttc cttattggaa ggagaaaaaa aggggtacat acatgtaaat acttgctgca     7980

gcatttaata tgtttaattt tgtgttaagc tttttgttgc atcgtgaaca catttattgt     8040

taccaatgga caatgagttc attaagactg ttcaactagg tcagattttt acatctcttt     8100

ctagcaagaa gagacaagat tttgtgcatt tgtacaaatg ttaatatcac tgcaattcca     8160

atataataaa gcactcaaat gcaaataaaa aaaaaaaaaa aaaaaaaaaa                8210


<210>  2282
<211>  2360
<212>  DNA
<213>  homo sapiens

<400>  2282
cagacggcca tttgtggcgg cgctggaggc tgcgttcggc aggcgctgcg gagacgcgta       60

gaggagcgcg ccccccggcc gctgccgccc ctggcccgtg ccgtcacccc gcttctccgc      120

gcctcgggcg gtacccagcc agtccccagc gccgcgctac cgcgctgacc ggccctccag      180

acgcctcccg gtacccggga ccccagcccg gccgctcgcc cgcagcccgc cggccgcaca      240

cgtccccgga gccgggccta gggcgggcgg cagcggcggc tcggcgcagt caggctgggc      300

tctgtagcgt ccccatggcc gcggccggct ggcgggacgg ctccggccag gagaagtacc      360

ggctcgtggt ggtcggcggg ggcggcgtgg gcaagtcggc gctcaccatc cagttcatcc      420

agtcctattt tgtaacggat tatgatccaa ccattgaaga ttcttacaca aagcagtgtg      480

tgatagatga cagagcagcc cggctagata ttttggatac agcaggacaa gaagagtttg      540

gagccatgag agaacagtat atgaggactg gcgaaggctt cctgttggtc ttttcagtca      600

cagatagagg cagttttgaa gaaatctata agtttcaaag acagattctc agagtaaagg      660

atcgtgatga gttcccaatg attttaattg gtaataaagc agatctggat catcaaagac      720

aggtaacaca ggaagaagga caacagttag cacggcagct taaggtaaca tacatggagg      780

catcagcaaa gattaggatg aatgtagatc aagctttcca tgaacttgtc cgggttatca      840

ggaaatttca agagcaggaa tgtcctcctt caccagaacc aacacggaaa gaaaaagaca      900

agaaaggctg ccattgtgtc attttctaga atcccttcag ttttagctac caacggccag      960

gaaaagccct catcttctct ttctctcctc agtttacatc ttgttggtac ctttctagcc     1020

ttagacaaat gatcaccatg ttagccttag acgaagaagc tggctagtcc tttctgtgaa     1080

gctaatacaa tggtcatttc cagacaaatt taaaggaaac actaaggctg cttcaaagat     1140

tatctgattc ctttaaaata tatgtctata tacacagaca tgctcttttt ttaagtgctt     1200

acattttaat agagatgaat cagttttgga atctaagctg tttgccaagc tgaagctaca     1260

ggttgtgaaa taatttttaa cttttggaat catactgcct actgttactc taaatagaaa     1320

tatagggttt tttttaatgt gaatttttgc ctatctttaa acatttcaat gtcagccttt     1380

gttaacctta aatacactga attgaatcta caaaagtgaa ccatctcaga cctttactga     1440

tactacaact tttgttttct gatggccaaa ataccaaatg cctgttgtat ttatggatta     1500

aaaactgctt ataaaaccct gtgttactac tcctactctt ggagatgata atattctatg     1560

tggtcaaata tttggactca tttaggactt agatatttca gtgtacttga ttttttaatt     1620

taactctttt tcacagccac gctaagggta aaaaggaata atttccttct gtcttccttt     1680

tcaagtattt ctgggtaagg gattcaaaaa actaaaactg tttttgtttg taatataaaa     1740

tatggaattg atctttccag ggtcagagat gattaatgtt tttgctatat acttttatac     1800

attattttct tatcaaacta gttaacaagt atttttatat gtttgtaagc agatatgctt     1860

tcatagcata ccttgtgtat atgtaaagat aagtatttaa ttctcactgt tcacttttaa     1920

ctgacaaaga aaaacaagtg gaaactacag aaactgtggt agaactttta cttgctggtc     1980

tggtcttggt tgtacccatc tttggccagt cacataacta ctcaagaaac cttcccaata     2040

gagtacaaca ggatgagact ctgaaatcac tttcagtatt ccctgctaga tattgattgt     2100

tatttcaagt attaagtgta agcttttaat ggataattag tataactgtg gatggcatct     2160

gattttgttt ttaattctgt ggattgtgtt taagcaattc aatagtatgt tcctgatttt     2220

gagatgctaa gtggtattgc acagttgtca ctttatcaag tgtgtacaac agtcccatga     2280

agtttataga gcataccctt gtatagcttc aggtgctaga attaaaattg atctgttatc     2340

acaagaaaaa aaaaaaaaaa                                                 2360


<210>  2283
<211>  2908
<212>  DNA
<213>  homo sapiens

<400>  2283
agagacgaga agagaggagg ggaggcctcc tccgccgccg ccatcttgga ccgggcccgg       60

tcagcttccg cggagccatc ggcagacgcc gcggcctccc ttgagccccg acccccgtcg      120

tcagaacaac cccgggccca ctcccccaac cccacttccg cttcgcgccg ctatcgcgat      180

agcgcccggg cccggggcgc gagaaaaagg cggcgggcgc tcgcctcccc cgcctgtcgc      240

gatacgctcc tcagcggcgg cgccagctcc tgtgcgtccg tctccaagag agtatgaaga      300

gagtgcgtct gtagggcagg gaagatggcg gacaagcgca aactccaagg tgagattgat      360

cgctgcctca agaaggtgtc cgagggcgtg gagcagtttg aagatatttg gcagaagctc      420

cacaatgcag ccaacgcgaa ccagaaagaa aagtatgagg ctgacctaaa gaaggagatt      480

aagaagctac aacggctgag ggaccaaatc aagacatggg tagcgtccaa cgagatcaag      540

gacaagaggc agcttataga caaccgcaag ctcattgaga cgcaaatgga acggttcaaa      600

gttgtggaac gagagaccaa aaccaaagct tacagcaaag agggcctggg cctggcccag      660

aaggtagatc ctgcccagaa ggagaaggaa gaggttggcc agtggctcac gaataccatc      720

gacacgctca acatgcaggt ggaccagttt gagagtgaag tggagtcact gtcagtgcag      780

acacgcaaga agaagggcga caaggataag caggaccgga ttgagggctt gaagcggcac      840

atcgagaagc accgctacca cgtgcgcatg ctagagacca tcctgcgcat gctggacaat      900

gactccatcc tcgttgacgc catccgcaag atcaaggacg acgttgagta ctatgttgac      960

tcatcccagg accccgactt cgaggagaac gagtttctct acgatgacct ggacctcgag     1020

gacattccac aggcgctggt cgccacctcc ccccccagcc acagccacat ggaggatgag     1080

atcttcaacc agtccagcag cacgcccacc tcaaccacct ccagctctcc catcccgccc     1140

agcccagcca actgtaccac ggaaaactct gaagatgata agaagagggg acgttccaca     1200

gacagtgaag tcagccagtc tccagccaaa aacggctcca agcctgtcca cagcaaccag     1260

caccctcagt ccccagctgt gccgcccacc tacccctccg gccccccgcc tgctgcctct     1320

gccttgagca ccactcctgg caacaatggg gtccccgccc ccgcagcacc cccaagtgcc     1380

ctgggcccca aggccagtcc agctcccagc cacaactcgg gcacccctgc tccctatgcc     1440

caggctgtgg ccccaccagc tcccagtggg cccagcacga cccagccccg gccccccagc     1500

gtccagccta gcggaggcgg aggcggcggc agcggaggtg gagggagcag cagcagtagt     1560

aacagcagtg ccggtggagg ggctggcaag cagaatggcg ccaccagtta cagctcagtt     1620

gtggcagaca gcccggcaga ggtggctttg agcagcagtg ggggcaacaa tgccagcagc     1680

caggccttgg gccccccttc cggcccccac aacccacctc ccagcacctc gaaggaaccc     1740

agtgcggcag ccccaacggg ggctgggggc gtggccccag gctcagggaa caactcaggg     1800

ggacccagcc tcctggtgcc actgcctgtg aatcctccca gctccccaac gcccagcttc     1860

agtgatgcca aggcagccgg tgccctgctc aatgggcctc cacagttcag caccgcccca     1920

gaaatcaagg cccctgagcc tctgagctcc ttgaagtcca tggcggaacg ggcagccatc     1980

agctctggca ttgaggaccc tgtgccaacg ctgcacctga ccgagcgaga catcatcctg     2040

agcagtacat cagcacctcc ggcctcagcc cagccgcccc tgcagctgtc agaggtgaac     2100

ataccgctgt cgctgggtgt ctgtccactg ggccctgtgc ccctcaccaa ggagcagctc     2160

tatcagcagg ccatggaaga ggccgcctgg caccacatgc ctcacccctc tgactctgag     2220

cgtattcggc agtacctccc ccggaacccc tgtccgacgc ccccctacca ccaccagatg     2280

ccacccccac actcggacac tgtggaattc taccagcgcc tgtcgaccga gacactcttc     2340

ttcatcttct actatctgga gggcactaag gcacagtatc tggcagccaa ggccctaaag     2400

aagcagtcat ggcgattcca caccaagtac atgatgtggt tccagaggca cgaggagccc     2460

aagaccatca ctgacgagtt tgagcagggc acctacatct actttgacta cgagaagtgg     2520

ggccagcgga agaaggaagg cttcaccttt gagtaccgct acctggagga ccgggacctc     2580

cagtgacacc ggcccctccc tctacccacc cccttccccc gcatgctgat ccccctgccc     2640

aggtgagggc cctgccctgg aagactggag ggaggcccca agccacgggg catccccctc     2700

tcccaggaag cagggagggg gccgggaggt tttcctctca gccccaccct gggggcccgg     2760

gggcgagggc tgccccctcc tcccctcccc agtgagggac attttttggt aaacctattt     2820

tcattttgga aaatatttat gaataaatag ttttatatga cggctggcag cagcggcctc     2880

tcctgtaaaa aaaaaaaaaa aaaaaaaa                                        2908


<210>  2284
<211>  2010
<212>  DNA
<213>  homo sapiens

<400>  2284
gccggggtct aggcaccacg gtggctggcg gcctgcgggc ggcgctgtgg cccgtcgggc       60

ggctccacag agccgcccta gccttccgcc ttccccaagc caacgtctcc gccgtcggct      120

ccgcggcgcc gccatggccg acgtggaaga cggagaggaa acctgcgccc tggcctctca      180

ctccgggagc tcaggctcca agtcgggagg cgacaagatg ttctccctca agaagtggaa      240

cgcggtggcc atgtggagct gggacgtgga gtgcgatacg tgcgccatct gcagggtcca      300

ggtgatggat gcctgtctta gatgtcaagc tgaaaacaaa caagaggact gtgttgtggt      360

ctggggagaa tgtaatcatt ccttccacaa ctgctgcatg tccctgtggg tgaaacagaa      420

caatcgctgc cctctctgcc agcaggactg ggtggtccaa agaatcggca aatgagagtg      480

gttagaaggc ttcttagcgc agttgttcag agccctggtg gatcttgtaa tccagtgccc      540

tacaaaggct agaacactac aggggatgaa ttcttcaaat aggagccgat ggatctgtgg      600

tcctttggga ctcatcaaag ccttggttta gcattttgtc agttttatct tcagaaattc      660

tctgcgatta agaagataat ttattaaagg tggtccttcc tacctctgtg gtgtgtgtcg      720

cgcacacagc ttagaagtgc tataaaaaag gaaagagctc caaattgaat cacctttata      780

atttacccat ttctatacaa caggcagtgg aagcagtttc agagaacttt ttgcatgctt      840

atggttgatc agttaaaaaa gaatgttaca gtaacaaata aagtgcagtt taaaacccaa      900

ctcttactct taatttgttc ctaatacgta tttttggcag ggagagggaa cggtccatga      960

aatctttatg tgatataagg attttaagtt tgggccagtg aacagggtaa ataaaattta     1020

acttttgagc atatggaatt ttgattgcct ttaaagttac tattctgtat cattgattca     1080

tcaagaaaac ctagatctgc actcacctca ctgttcaatc attgagtggt aaaggacaga     1140

agtattttct agttctggtc agatgatata attttttttt tttttttttg tgggggtgaa     1200

gtcttgctct gccacccagg ctggagtgca gtggcatgat gtcaactcac tgcaacctcc     1260

gcctcccggg ttcaagtgat tctcctgcct cagcctcccg agtagctggg attacaggtg     1320

tgtgccacca cacccggcta atttttgtat ttttagtaga gacgggattt ccccatgttg     1380

gccaggctgg tctcaaactc ctgacctcag gtgattcgcc cacctcagcc tcccaaagtg     1440

ctgggattac aggtgtgggc cactgcacct ggcccagatg atataattta actgtgtttt     1500

aggtaacatg ttaatgaggg aaaatgttta ccagtgtagc attggatcaa aaagtttatc     1560

acacagtgtt ttaataaatg gtttattctg cttaccttat ttgaattgtc attataattt     1620

tatatgcaac cttaatttgt caagtaaata ctttcattta atttgaaaga attcatattc     1680

atttgctctt tcatttgaca ataataaaat ttaaggttta ttacctggaa agagtgcaag     1740

aaaatactaa acaactttat caaactgatt cacactgagg ggaggttatt ttgtaacaaa     1800

taatggacca caagttcatt ttgtattctt ctgtagtaga ggctactgat atgaatttaa     1860

gaaaaaacct tagaatctta acttttcaca tctgcagatg cagtgtgcca ttctgaattt     1920

ttcaatctaa gggatgtgga tacatagaat gtttaaaaag ataacaatta gaatgaaaaa     1980

ttaaaattat gtatgctttt aaaaaaaaaa                                      2010


<210>  2285
<211>  4229
<212>  DNA
<213>  homo sapiens

<400>  2285
tagagaacgt ggctcccgcg ggggcgctcg gagccgccgc acaggtagcg agagcgcggc       60

gccttctcct tcctttgtga gccgccgggc agggcaccga cctcgggttc tcccggcgcc      120

tccactgcag ggatctctag cctcgcacct cctcccctcg tcgcctgccc accctctgct      180

cctctcctgg cgccggggac cctgcccctt tgcgcctttt cctggctctg cctcggcttc      240

catttttctc tgcttccgaa aagccagtgg ggaagggcgg gggagacctg ccagtcctcc      300

cagacttctc ccgggttgct ccagctggcc ctcctcgccc cttcccggga gaggcacatg      360

gagagacatg aatcagggga gtggactgga cctgctgaag atctcatatg gaaaaggagc      420

cagaaggaaa aacagattta aaggatctga tggaagcacg tcatctgata ctacctcaaa      480

tagttttgtt cgccagggtt cggcagactc ctacactagc cgtccatccg attccgatgt      540

atctctggag gaggaccggg aggcagtgcg cagagaagcg gagcggcagg cccaggcaca      600

gttggaaaaa gcaaagacaa agcccgttgc atttgcggtt cggacaaatg tcagctacag      660

tgcggcccat gaagatgatg ttccagtgcc tggcatggcc atctcattcg aagcaaaaga      720

ttttctgcat gttaaggaaa aatttaacaa tgactggtgg atagggcgat tggtaaaaga      780

aggctgtgaa atcggattca ttccaagccc agtcaaacta gaaaacatga ggctgcagca      840

tgaacagaga gccaagcaag ggaaattcta ctccagtaaa tcaggaggaa attcatcatc      900

cagtttgggt gacatagtac ctagttccag aaaatcaaca cctccatcat ctggtgcaaa      960

atctgcagat gaacaagacc agtggaaaac tgcaggcttg ttttggcggt ttactacaga     1020

gcacactcct ccgtatgatg tggtaccttc catgcgacca gtggtcctag tgggcccttc     1080

tctgaagggc tacgaggtca cagatatgat gcaaaaagcg ctgtttgatt ttttaaaaca     1140

cagatttgaa gggcggatat ccatcacaag ggtcaccgct gacatctcgc ttgccaaacg     1200

ctcggtatta aacaatccca gtaagcacgc aataatagaa agatccaaca caaggtcaag     1260

cttagcggaa gttcagagtg aaatcgaaag gatttttgaa cttgcaagaa cattgcagtt     1320

ggtggtcctt gacgcggata caattaatca tccagctcaa ctcagtaaaa cctccttggc     1380

ccctattata gtatatgtaa agatttcttc tcctaaggtt ttacaaaggt taataaaatc     1440

tcgagggaaa tctcaagcta aacacctcaa cgtccagatg gtagcagctg ataaactggc     1500

tcagtgtcct ccagagctgt tcgatgtgat cttggatgag aaccagcttg aggatgcctg     1560

tgagcacctt gccgactatc tggaggccta ctggaaggcc acccatcctc ccagcagtag     1620

cctccccaac cctctcctta gccgtacatt agccacttca agtctgcctc ttagccccac     1680

cctagcctct aattcacagg gttctcaagg tgatcagagg actgatcgct ccgctcctat     1740

ccgttctgct tcccaagctg aagaagaacc tagtgtggaa ccagtcaaga aatcccagca     1800

ccgctcttcc tcctcagccc cacaccacaa ccatcgcagt gggacaagtc gcggcctctc     1860

caggcaagag acatttgact cggaaaccca ggagagtcga gactctgcct acgtagagcc     1920

aaaggaagat tattcccatg accacgtgga ccactatgcc tcacaccgtg accacaacca     1980

cagagacgag acccacggga gcagtgacca cagacacagg gagtcccggc accgttcccg     2040

ggacgtggat cgagagcagg accacaacga gtgcaacaag cagcgcagcc gtcataaatc     2100

caaggatcgc tactgtgaaa aggatggaga agtgatatca aaaaaacgga atgaggctgg     2160

ggagtggaac agggatgttt acatccgcca atgagttttg cccgtttgtg tttttttttt     2220

tttttttttg aagtcttgta taactaacag catccccaaa acaaagtctt tggggtctac     2280

actgcaatca tatgtgatct gtcttgtaat attttgtatt attgctgttg cttgaatagc     2340

aatagcatgg atagagtatt gagatacttt ttcttttgta agtgctacat aaattggcct     2400

ggtatggctg cagtcctccg gttgcatact ggactcttca aaaactgttt tgggtagctg     2460

ccacttgaac aaaatctgtt gccacccagg tgatgttagt gttttaagaa atgtagttga     2520

tgtatccaac aagccagaat cagcacagat aaaaagtgga atttcttgtt tctccagatt     2580

tttaatacgt taatacgcag gcatctgatt tgcatattca ttcatggacc actgtttctt     2640

gcttgtacct ctggctgact aaatttgggg acagattcag tcttgcctta cacaaagggg     2700

atcataaagt tagaatctat tttctatgta ctagtactgt gtactgtata gacagtttgt     2760

aaatgttatt tctgcaaaca aacaccttct tattatatat ataatatata tatatatcag     2820

tttgatcaca ctattttaga gtcttaatgc caagtcagca gatttgcttt atgaattaca     2880

gggactagaa atgcccacat tcaggaaatt tgtaataaca ttgtctagac acctatcctc     2940

attctagtag aaagtgtgta catactgtaa atatgtgtga ttgcttgact tgaaaaggtt     3000

tgaattctga atgttatacc atccttgtaa gtaagtttgt aatttccacc ataaattatg     3060

gtaaatataa aactccagag gttgttctac tccatacagt tcacactgat tgtgacacat     3120

tcttagtagc tagtgtctgt tctagtcact gcactggagt ctacgagccg gaactcgcta     3180

tatgcacgtg tgtgtgtccg tatgtaagaa agtgtgcacc gagtgactga atggttgaga     3240

tgaattggaa tgctgaagac taacgaagaa actagagact gatatcgagc attctgccca     3300

cctcgctctg tatttaatta attgtgctat atgttgcttt aacaacccat tgagcagtca     3360

gggaatgtga gtaagcttgc tgccaaaggt aactaggaaa gcattcatct gctgcctcct     3420

tgtttttgct cctagagagt gaaaatacag gcaattttac tgtgagtgtt tcactggaaa     3480

tgtacaatct ttgtgtgtta gagtatttgt tttagtaaga aatgtttaca cagcttgtgg     3540

aattatttcg tgggaaaata aatttttata acttctccca cttcaatttc taaccttgcc     3600

tattgttcct gttgtttgtt tacctcccag ttacctacca ttcctcccca ccaccgactc     3660

cagcaggttc actgtctgtc agaacccaga agtgcttctt ataaccaaag tttctgttct     3720

tcagaagaaa tcagggcaaa atggggtgac ttgaagtgaa taaaatgtta agaatattat     3780

cctacataag acatgtacac agaaggggaa ccttgaagac attatctcca tgcctcaatt     3840

acactgctgt aagaagctta caatgtcatc atgtttaagg ctaagacctt ttccgtgtct     3900

caagtgtata ttttgtccag ttataactgg atggtaagac agtattaaga gtgcaagtac     3960

ctggcacttg aagtttgtcc caggaaaatg cctgtgtata attacctaac ttcagatctg     4020

cacattaact tatttaacaa aataaatcag ccgggcgcag tggctcatgc ctgtaatccc     4080

agcaatttgg gaggctgagg agggtggatc acctgaggtc aggagttcaa gaccagcctg     4140

gccaacgtgg cgaaaccccg tctctactaa aaagataaaa aattagccag gtgtggtggt     4200

gcacacctgt aatcccagct acttgggag                                       4229


<210>  2286
<211>  3206
<212>  DNA
<213>  homo sapiens

<400>  2286
aataaatttc tctgtgattg gttggtgaag gttttcaaac cggagctgtg ggcgcggcgc       60

tgctctgccg ttgggtgagg cgcggagcga agtgaagggt ggcccaggtg gggccaggct      120

gactgaagtg agtagtgggg gtgccagacc aggtgcgtct gccgctggat tgtgatagga      180

agcagagtgt tcgtgtgaaa gatggatact atgatgctga atgtgcggaa tctgtttgag      240

cagcttgtgc gccgggtgga gattctcagt gaaggaaatg aagtccaatt tatccagttg      300

gcgaaggact ttgaggattt ccgtaaaaag tggcagagga ctgaccatga gctggggaaa      360

tacaaggatc ttttgatgaa agcagagact gagcgaagtg ctctggatgt taagctgaag      420

catgcacgta atcaggtgga tgtagagatc aaacggagac agagagctga ggctgactgc      480

gaaaagctgg aacgacagat tcagctgatt cgagagatgc tcatgtgtga cacatctggc      540

agcattcaac taagcgagga gcaaaaatca gctctggctt ttctcaacag aggccaacca      600

tccagcagca atgctgggaa caaaagacta tcaaccattg atgaatctgg ttccatttta      660

tcagatatca gctttgacaa gactgatgaa tcactggatt gggactcttc tttggtgaag      720

actttcaaac tgaagaagag agaaaagagg cgctctacta gccgacagtt tgttgatggt      780

ccccctggac ctgtaaagaa aactcgttcc attggctctg cagtagacca ggggaatgaa      840

tccatagttg caaaaactac agtgactgtt cccaatgatg gcgggcccat cgaagctgtg      900

tccactattg agactgtgcc atattggacc aggagccgaa ggaaaacagg tactttacaa      960

ccttggaaca gtgactccac cctgaacagc aggcagctgg agccaagaac tgagacagac     1020

agtgtgggca cgccacagag taatggaggg atgcgcctgc atgactttgt ttctaagacg     1080

gttattaaac ctgaatcctg tgttccatgt ggaaagcgga taaaatttgg caaattatct     1140

ctgaagtgtc gagactgtcg tgtggtctct catccagaat gtcgggaccg ctgtcccctt     1200

ccctgcattc ctaccctgat aggaacacct gtcaagattg gagagggaat gctggcagac     1260

tttgtgtccc agacttctcc aatgatcccc tccattgttg tgcattgtgt aaatgagatt     1320

gagcaaagag gtctgactga gacaggcctg tataggatct ctggctgtga ccgcacagta     1380

aaagagctga aagagaaatt cctcagagtg aaaactgtac ccctcctcag caaagtggat     1440

gatatccatg ctatctgtag ccttctaaaa gactttcttc gaaacctcaa agaacctctt     1500

ctgacctttc gccttaacag agcctttatg gaagcagcag aaatcacaga tgaagacaac     1560

agcatagctg ccatgtacca agctgttggt gaactgcccc aggccaacag ggacacatta     1620

gctttcctca tgattcactt gcagagagtg gctcagagtc cacatactaa aatggatgtt     1680

gccaatctgg ctaaagtctt tggccctaca atagtggccc atgctgtgcc caatccagac     1740

ccagtgacaa tgttacagga catcaagcgt caacccaagg tggttgagcg cctgctttcc     1800

ttgcctctgg agtattggag tcagttcatg atggtggagc aagagaacat tgacccccta     1860

catgtcattg aaaactcaaa tgccttttca acaccacaga caccagatat taaagtgagt     1920

ttactgggac ctgtgaccac tcctgaacat cagcttctca agactccttc atctagttcc     1980

ctgtcacaga gagtccgttc caccctcacc aagaacactc ctagatttgg gagcaaaagc     2040

aagtctgcca ctaacctagg acgacaaggc aacttttttg cttctccaat gctcaagtga     2100

agtcacatct gcctgttact tcccagcatt gactgactat aagaaaggac acatctgtac     2160

tctgctctgc agcctcctgt actcattact acttttagca ttctccaggc ttttactcaa     2220

gtttaattgt gcatgagggt tttattaaaa ctatatatat ctccccttcc ttctcctcaa     2280

gtcacataat atcagcactt tgtgctggtc attgttggga gcttttagat gagacatctt     2340

tccaggggta gaagggttag tatggaattg gttgtgattc tttttgggga agggggttat     2400

tgttcctttg gcttaaagcc aaatgctgct catagaatga tctttctcta gtttcattta     2460

gaactgattt ccgtgagaca atgacagaaa ccctacctat ctgataagat tagcttgtct     2520

cagggtggga agtgggaggg cagggcaaag aaaggattag accagaggat ttaggatgcc     2580

tccttctaag aaccagaagt tctcattccc cattatgaac tgagctataa tatggagctt     2640

tcataaaaat gggatgcatt gaggacagaa ctagtgatgg gagtatgcgt agctttgatt     2700

tggatgatta ggtctttaat agtgttgagt ggcacaacct tgtaaatgtg aaagtacaac     2760

tcgtatttat ctctgatgtg ctgctggctg aactttgggt tcatttgggg tcaaagccag     2820

tttttctttt aaaattgaat tcattctgat gcttggcccc cataccccca accttgtcca     2880

gtggagccca acttctaaag gtcaatatat catcctttgg catcccaact aacaataaag     2940

agtaggctat aagggaagat tgtcaatatt ttgtggtaag aaaagctaca gtcatttttt     3000

ctttgcactt tggatgctga aatttttccc atggaacata gccacatcta gatagatgtg     3060

agctttttct tctgttaaaa ttattcttaa tgtctgtaaa aacgattttc ttctgtagaa     3120

tgtttgactt cgtattgacc cttatctgta aaacacctat ttgggataat atttggaaaa     3180

aaagtaaata gctttttcaa aatgaa                                          3206


<210>  2287
<211>  2277
<212>  DNA
<213>  homo sapiens

<400>  2287
gagcgacgcc cacggcctgt ctcggccacc agcgtgttcc agcgagcgcc cagccacctc       60

gctcgcagcc tccccagcgc agcagcccgg ctgtgggcct gcggcagccg ggtcttcctg      120

gtccccacct cctggggccg acgggcggca ggaaggggct cggcgggacg cgccatcagg      180

gacctgagga ggaacaacgg aacgcgttcg gaacggcctg gactcccgag actcacccga      240

ctcgtggcca caccgggaga actgaagcgg cagtagccgg cggagacgcc cgacccgaag      300

gccggctgct agggagcaga cagctgaacc gcttgccaga cgccgaaacc cagtgacgcc      360

ctccaccgct ccaccgtgct cccggctcct cgcccccgcc gcccgcgggc cccaaggcgc      420

atgcgccgcc tgtcctggag gggcccattt ccgtccgtcg tggggggagg cacagtgagt      480

ccactggggc acggcagcgt ctaagccaca agccgagcac ataagccagg tcctaacgga      540

gcctatgtgt aagtccacta ctggtgcaag gttgcacact tctaagaaga gcggcgtggg      600

gggctcggcg accttcgctt cagtcgctcc cccgtgcagt cccctgtgcc caagacacag      660

cctgatgctt gtgctccggt gggcggagct tggaggcggc gggaactgca attggtggct      720

ttgaaggcgc ggcgagcggg aacagctctt gaggagtgag actgcaggag atgtgggccg      780

tgccaaagag atggatgaga ctgttgctga gttcatcaag aggaccatct tgaaaatccc      840

catgaatgaa ctgacaacaa tcctgaaggc ctgggatttt ttgtctgaaa atcaactgca      900

gactgtaaat ttccgacaga gaaaggaatc tgtagttcag cacttgatcc atctgtgtga      960

ggaaaagcgt gcaagtatca gtgatgctgc cctgttagac atcatttata tgcaatttca     1020

tcagcaccag aaagtttggg aagtttttca gatgagtaaa ggaccaggtg aagatgttga     1080

cctttttgat atgaaacaat ttaaaaattc gttcaagaaa attcttcaga gagcattaaa     1140

aaatgtgaca gtcagcttca gagaaactga ggagaatgca gtctggattc gaattgcctg     1200

gggaacacag tacacaaagc caaaccagta caaacctacc tacgtggtgt actactccca     1260

gactccgtac gccttcacgt cctcctccat gctgaggcgc aatacaccgc ttctgggtca     1320

ggcgctgaca attgctagca aacaccatca gattgtgaaa atggacctga gaagtcggta     1380

tctggactct cttaaggcta ttgtttttaa acagtataat cagacctttg aaactcacaa     1440

ctctacgaca cctctacagg aaagaagcct tggactagat ataaatatgg attcaaggat     1500

cattcatgaa aacatagtag aaaaagagag agtccaacga ataactcaag aaacatttgg     1560

agattatcct caaccacaac tagaatttgc acaatataag cttgaaacga aattcaaaag     1620

tggtttaaat gggagcatct tggctgagag ggaagaaccc ctccgatgcc taataaagtt     1680

ctctagccca catcttctgg aagcattgaa atccttagca ccagcggcac ttgtttgcag     1740

gatccaaaag ctgctctgct attctggaag ccacagtcaa gggacccagg acccgagcag     1800

ctggcagaag gacttgtacc ttctgtttgt cccattgtat ccaagatgtt aaaatcatga     1860

tgtcacaaca tttagacatt taaatggtta atcaaatgta tgtctctcct gatatacagc     1920

taactgctat agactaatgc aggcctcctt gttaaaatgg accctttgtt actcaaattt     1980

gaccaatctt ggaagcttgg atgtgcactg acttgacaac cactttttgt gggacataac     2040

actctagaca caggtgcttc tagctctaag gggaacagat aactaatctg tggccaacca     2100

accaatgatt aatcagctat gctgcctcgg atcttgatca aaaaaggaaa atgtgaaaag     2160

tgatacacaa aatggcatca ctttggttca gagctctaaa atggagttgg gaagccattc     2220

taagaaggac tgcctgcaca atctgcaact tgcaaaacac aaaaaaaaaa aaaaaaa        2277


<210>  2288
<211>  4663
<212>  DNA
<213>  homo sapiens

<400>  2288
gagcgacgcc cacggcctgt ctcggccacc agcgtgttcc agcgagcgcc cagccacctc       60

gctcgcagcc tccccagcgc agcagcccgg ctgtgggcct gcggcagccg ggtcttcctg      120

gtccccacct cctggggccg acgggcggca ggaaggggct cggcgggacg cgccatcagg      180

gacctgagga ggaacaacgg aacgcgttcg gaacggcctg gactcccgag actcacccga      240

ctcgtggcca caccgggaga actgaagcgg cagtagccgg cggagacgcc cgacccgaag      300

gccggctgct agggagcaga cagctgaacc gcttgccaga cgccgaaacc cagtgacgcc      360

ctccaccgct ccaccgtgct cccggctcct cgcccccgcc gcccgcgggc cccaaggcgc      420

atgcgccgcc tgtcctggag gggcccattt ccgtccgtcg tggggggagg cacagtgagt      480

ccactggggc acggcagcgt ctaagccaca agccgagcac ataagccagg tcctaacgga      540

gcctatgtgt aagtccacta ctggtgcaag gttgcacact tctaagaaga gcggcgtggg      600

gggctcggcg accttcgctt cagtcgctcc cccgtgcagt cccctgtgcc caagacacag      660

cctgatgctt gtgctccggt gggcggagct tggaggcggc gggaactgca attggtggct      720

ttgaaggcgc ggcgagcggg aacagctctt gaggagtgag actgcaggag atgtgggccg      780

tgccaaagag atggatgaga ctgttgctga gttcatcaag aggaccatct tgaaaatccc      840

catgaatgaa ctgacaacaa tcctgaaggc ctgggatttt ttgtctgaaa atcaactgca      900

gactgtaaat ttccgacaga gaaaggaatc tgtagttcag cacttgatcc atctgtgtga      960

ggaaaagcgt gcaagtatca gtgatgctgc cctgttagac atcatttata tgcaatttca     1020

tcagcaccag aaagtttggg aagtttttca gatgagtaaa ggaccaggtg aagatgttga     1080

cctttttgat atgaaacaat ttaaaaattc gttcaagaaa attcttcaga gagcattaaa     1140

aaatgtgaca gtcagcttca gagaaactga ggagaatgca gtctggattc gaattgcctg     1200

gggaacacag tacacaaagc caaaccagta caaacctacc tacgtggtgt actactccca     1260

gactccgtac gccttcacgt cctcctccat gctgaggcgc aatacaccgc ttctgggtca     1320

ggcgctgaca attgctagca aacaccatca gattgtgaaa atggacctga gaagtcggta     1380

tctggactct cttaaggcta ttgtttttaa acagtataat cagacctttg aaactcacaa     1440

ctctacgaca cctctacagg aaagaagcct tggactagat ataaatatgg attcaaggat     1500

cattcatgaa aacatagtag aaaaagagag agtccaacga ataactcaag aaacatttgg     1560

agattatcct caaccacaac tagaatttgc acaatataag cttgaaacga aattcaaaag     1620

tggtttaaat gggagcatct tggctgagag ggaagaaccc ctccgatgcc taataaagtt     1680

ctctagccca catcttctgg aagcattgaa atccttagca ccagcgggta ttgcagatgc     1740

tccactttct ccactgctca cttgcatacc caacaagaga atgaattatt ttaaaattag     1800

agataaataa gacgtgcgtg gtttcttaag cacagctcct ccttcttgat attgcacatg     1860

cacttcagtt catggctagc tgtatagctt ccgtctgtaa acttgtattt tcaagaatcc     1920

ttggtattga atttttagaa atgctcacat aattgttggg actgattcat tcctccacga     1980

tatgcctcct ctctctgata tcctgctaac tgtagccgtt gtggcatttg agatgacagg     2040

acatatatat atatggcccc acacttgacc ttgagtgcct gaatgctctg aaatcaagca     2100

tatggcacag cgctcaagac ttttgggttt gtgtcctttt ttctatggct gtctcttctc     2160

aattctggag aggtctggtt ccagtggctg gtttccaggg attgattctt aagctctgga     2220

tcacagagag aagcaacaag gaactatact caactcaaaa ctttttagga gaatcatgaa     2280

attggtctat tcaaaggatg gagttgagtc cattctgtta ttgttgcaag aggttgcata     2340

tttggtgagt cagttatata aaatagtgtt cttattgtaa atatgatact tctcataatc     2400

tattttatca tgtgtataac attcaaactg acaaatatat tgacttatga ataaaggtgt     2460

caaaaaactg gcacatcagt taattttgat caaagtactt cagtgatcat cactaaatac     2520

cctatctttt taaaaatttt ttcctttcta attttttatt tctttattta tttattgaga     2580

cagggtctca ctgtgtcacc caagctggag tgcagtggca tgatcatggc tcactgcagc     2640

ctggacctcc caggctcaag tgatccttcc acctcagcct cccgaatagc tgggattaca     2700

gacgcgctcc atcctgccca gctaattttt tttttgtttg ttttttgttt tttgagacaa     2760

gtctccttct atcgcccagg ctggagtgca atggcacaat cttggctccc tgcaacctct     2820

gcctcctggg ttgaagagat tctcctgcct cagcctctga gtagctggga ctacaggcct     2880

gcaccaccat gcccagctaa tttttgtatt tttagtagag acagggtttc tccatgttgc     2940

ccaggctgat ctcaaactcc tgggctcaag caatctgccc attttagcct cctaaaatgc     3000

tgggattata ggagtgtatt agtctattct catgctgcta ataaagatac ctaagactgg     3060

gtaattcaca aaggaaagag gcttaactga cgcacatttc cacgtggcca gggaggcctc     3120

acaatcatgg tggaaggcaa atgagaagca aagtcatgtc ttacatggcg gcaggcaaga     3180

gagcttgtgc agggaaactc ccatttataa aaccaccaga gctcatgaaa cttattcact     3240

accatgagaa tagtatgggg gaaatcgttc ccatgactca agtatctcca cctggccctg     3300

cccttgtcac atgggggtta ttacaattca aggtgacact tgtgtggaga cacagccaaa     3360

ccatatcaca ggcatgagct accacgcccg ccagcatgtc ttttttaaac attttaaaat     3420

ctattcttta tcttgtttca gagaggattt ggagttacag aaacacatta gactgggcat     3480

ggtggctcac acttgtaatc ccagcacttc aggaggtttc tcctagtgta ctctcacact     3540

tctgatacca gatatgtggg ggagggggtt tcccccacac attaagcaag tgtgaaacat     3600

gatatagaaa aatgacttca ctctgggccg ggtgtagtgg ctcacgcctg taatcctagc     3660

actttgggaa gccgaggtgg gcagatcacc cgaggtcagg agttcgagac cagcctagcc     3720

aacatggcaa aaccttgtct ctactaaaaa tagaaaaatt agttgggggt agtggcagcc     3780

gcctgtaatc ccagctattc gagaggctga ggcaggagaa ctggttgaac cggggaggca     3840

gaggttgcag tgagccaaga tcatgccact gcactctagc ctgggtgaca gagtgaaact     3900

ctgcctcaaa aaataaaata aaggccaggc atggtggctc acgcctataa tcccagcact     3960

ttcagaggcc aaggcaggtg ggtcacaagg tcaagagttt gagactagcc ttagcaacat     4020

ggtgaaggtg aaccccgact ctactaaaaa tacaaaaatt agctgggcct ggtggtgtgc     4080

acctgtaatc ccagctactt aggaggctga ggcaggagaa tcgcttgaac ccgggagaca     4140

taggttgcag tgagccgaga ctgcaccact gcactccagc ctaggtgaca gagtgagact     4200

ccatcttaaa aaataaataa ataaaataaa ataaatgaca tcactttggt tcagagctct     4260

aaaatggagg gaggaagcca ttctaaaaag gactccctac atgacctgca acttgaaaaa     4320

aaattaaaag ctccaaaaaa aaaacaatac aggagcttac cttgaacctt tgaattgggc     4380

caaattgcga tgaccactgc atcctggaaa attttatttc accagcacta caactcctca     4440

acagcaccaa ccaataaact atggattttt gtactaagcc agttgcctct ttcaaaacaa     4500

cttgtcaact tgtctaatca ccctcagctt tttttaaaaa cccctcctct accctctctc     4560

ttcagaacac aagtggcttc tagctgaatc tgtctcccaa attgcaattc ctaagacctc     4620

aataaaaaca ccttgtcttg ctgcaaaaaa aaaaaaaaaa aaa                       4663


<210>  2289
<211>  3227
<212>  DNA
<213>  homo sapiens

<400>  2289
cccactctgc agttgtctcc cgagcgctgg ctgcgccgcc cgagccgctg ggccggggaa       60

gcactggccg ttcgctcccg ggccggctcc gccaggcgct cgcaggcatg cagcccggga      120

gcaggaggcg ctccccgggc cgctgctgag ccggccgggg cggcggggac cagcgccagc      180

ggagcccctc ccaccttgcc ccggggcaga cgagcggcgc cccgacaccc cctcttctcc      240

cgcagccccg ccagcgccac cccccgcggg ccgcaggggc tcatgcagcc gccaagggag      300

aggctagtgg taacaggccg agctggatgg atgggtatgg ggagaggggc aggacgttca      360

gccctgggat tctggccgac cctcgccttc cttctctgca gcttccccgc agccacctcc      420

ccgtgcaaga tcctcaagtg caactctgag ttctggagcg ccacgtcggg cagccacgcc      480

ccagcctcag acgacacccc cgagttctgt gcagccttgc gcagctacgc cctgtgcacg      540

cggcggacgg cccgcacctg ccggggtgac ctggcctacc actcggccgt ccatggcata      600

gaggacctca tgagccagca caactgctcc aaggatggcc ccacctcgca gccacgcctg      660

cgcacgctcc caccggccgg agacagccag gagcgctcgg acagccccga gatctgccat      720

tacgagaaga gctttcacaa gcactcggcc acccccaact acacgcactg tggcctcttc      780

ggggacccac acctcaggac tttcaccgac cgcttccaga cctgcaaggt gcagggcgcc      840

tggccgctca tcgacaataa ttacctgaac gtgcaggtca ccaacacgcc tgtgctgccc      900

ggctcagcgg ccactgccac cagcaagctc accatcatct tcaagaactt ccaggagtgt      960

gtggaccaga aggtgtacca ggctgagatg gacgagctcc cggccgcctt cgtggatggc     1020

tctaagaacg gtggggacaa gcacggggcc aacagcctga agatcactga gaaggtgtca     1080

ggccagcacg tggagatcca ggccaagtac atcggcacca ccatcgtggt gcgccaggtg     1140

ggccgctacc tgacctttgc cgtccgcatg ccagaggaag tggtcaatgc tgtggaggac     1200

tgggacagcc agggtctcta cctctgcctg cggggctgcc ccctcaacca gcagatcgac     1260

ttccaggcct tccacaccaa tgctgagggc accggtgccc gcaggctggc agccgccagc     1320

cctgcaccca cagcccccga gaccttccca tacgagacag ccgtggccaa gtgcaaggag     1380

aagctgccgg tggaggacct gtactaccag gcctgcgtct tcgacctcct caccacgggc     1440

gacgtgaact tcacactggc cgcctactac gcgttggagg atgtcaagat gctccactcc     1500

aacaaagaca aactgcacct gtatgagagg actcgggacc tgccaggcag ggcggctgcg     1560

gggctgcccc tggccccccg gcccctcctg ggcgccctcg tcccgctcct ggccctgctc     1620

cctgtgttct gctagacgcg tagatgtgga gggaggcgcg ggctccgtcc tctcggcttc     1680

cccatgtgtg ggctgggacc gcccacgggg tgcagatctc ctggcgtgtc caccatggcc     1740

ccgcagaacg ccagggaccg cctgctgcca agggctcagg cacggacccc tccccttcta     1800

gtgcacgtga caaggttgtg gtgactggtg ccatgatgtt tgacagtaga gctgtgtgag     1860

agggagagca gctcccctcg ccccgcccct gcagtgtgaa tgtgtgaaac atcccctcag     1920

gctgaagccc cccaccccca ccagagacac actgggaacc gtcagagtca gctccttccc     1980

cctcgcaatg cactgaaagg cccggccgac tgctgctcgc cgatccgtgg ggccccctgt     2040

gcccgccaca cgcacgcaca cactcttaca cgagagcaca ctcgatcccc ctaggccagc     2100

ggggacaccc cagccacaca gggaggcatc cttggggctt ggccccaggc agggcaaccc     2160

cggggcgctg cttggcacct tagcagactg ctggaacctt ttggccagta ggtcgtgccc     2220

gcctggtgcc ttctggcctg tggcctccct gcccatgttc acctggctgc tgtgggtacc     2280

agtgcaggtc ccggttttca ggcacctgct cagctgcccg tctctggcct gggcccctgc     2340

cccttccacc ctgtgcttag aaagtcgaag tgcttggttc taaatgtcta aacagagaag     2400

agatccttga cttctgttcc tctctctcct gcagatgcaa gagctcctgg gcaggggtgc     2460

ctgggcccca gggtgtggca ggagacccag tggatggggc cagctggcct gccctgatcc     2520

tctgcttcct cctcacaacc ccaagagccc ccagcccggt ccatccacgt ctggagtctg     2580

gggagaggag cagggtctta ggactctcag ctctgagcat ccctggcagg gtcttcaacc     2640

tctaatctct tcccttaagc cctgtggcca cacagccagg agagacttgc cgctggctcc     2700

cgcctcattt cagcccaggg tgctcatcca ggggcccaga acagtcccac ctgtgctgct     2760

gtgcccacag cacaaagcca ggcttcactc ccaaaagtgc agccaggccc tggagggtga     2820

tcctgccagc agccctacag ctccacaccc tacccaccca tcggcagccc ctctgctgtt     2880

ccccagggac ctctcataca ctggccagga ggctgcagaa cgtgtgtctc cccctccctc     2940

caagaggtcc tgctccctct gccagaaccg tgtgtgggcg ggtgggaggg cgctcggggc     3000

ccggcccctc cctctccctg ctggttttag ttggtcccta tgttggaagt aaaaagtgaa     3060

gcactttatt ttggttgtgt ttgctcacgt tctgcttgga agtggggacc cctcactgcg     3120

tccacgtgtc tgcgacctgt gtggagtgtc accgcgtgta catactgtaa attatttatt     3180

aatggctaaa tgcaagtaaa gtttggtttt tttgttattt tctttta                   3227


<210>  2290
<211>  3060
<212>  DNA
<213>  homo sapiens

<400>  2290
gagcgcgccg ggcgcccgcg gccgaggtgg acggagcctc ccggctcgct gctcccgccg       60

gcggagcgag gctgcccttt cttcgcagcg tgatttattt tcttcttttt ttctgaactc      120

ttcttccagg gagaggctag tggtaacagg ccgagctgga tggatgggta tggggagagg      180

ggcaggacgt tcagccctgg gattctggcc gaccctcgcc ttccttctct gcagcttccc      240

cgcagccacc tccccgtgca agatcctcaa gtgcaactct gagttctgga gcgccacgtc      300

gggcagccac gccccagcct cagacgacac ccccgagttc tgtgcagcct tgcgcagcta      360

cgccctgtgc acgcggcgga cggcccgcac ctgccggggt gacctggcct accactcggc      420

cgtccatggc atagaggacc tcatgagcca gcacaactgc tccaaggatg gccccacctc      480

gcagccacgc ctgcgcacgc tcccaccggc cggagacagc caggagcgct cggacagccc      540

cgagatctgc cattacgaga agagctttca caagcactcg gccaccccca actacacgca      600

ctgtggcctc ttcggggacc cacacctcag gactttcacc gaccgcttcc agacctgcaa      660

ggtgcagggc gcctggccgc tcatcgacaa taattacctg aacgtgcagg tcaccaacac      720

gcctgtgctg cccggctcag cggccactgc caccagcaag ctcaccatca tcttcaagaa      780

cttccaggag tgtgtggacc agaaggtgta ccaggctgag atggacgagc tcccggccgc      840

cttcgtggat ggctctaaga acggtgggga caagcacggg gccaacagcc tgaagatcac      900

tgagaaggtg tcaggccagc acgtggagat ccaggccaag tacatcggca ccaccatcgt      960

ggtgcgccag gtgggccgct acctgacctt tgccgtccgc atgccagagg aagtggtcaa     1020

tgctgtggag gactgggaca gccagggtct ctacctctgc ctgcggggct gccccctcaa     1080

ccagcagatc gacttccagg ccttccacac caatgctgag ggcaccggtg cccgcaggct     1140

ggcagccgcc agccctgcac ccacagcccc cgagaccttc ccatacgaga cagccgtggc     1200

caagtgcaag gagaagctgc cggtggagga cctgtactac caggcctgcg tcttcgacct     1260

cctcaccacg ggcgacgtga acttcacact ggccgcctac tacgcgttgg aggatgtcaa     1320

gatgctccac tccaacaaag acaaactgca cctgtatgag aggactcggg acctgccagg     1380

cagggcggct gcggggctgc ccctggcccc ccggcccctc ctgggcgccc tcgtcccgct     1440

cctggccctg ctccctgtgt tctgctagac gcgtagatgt ggagggaggc gcgggctccg     1500

tcctctcggc ttccccatgt gtgggctggg accgcccacg gggtgcagat ctcctggcgt     1560

gtccaccatg gccccgcaga acgccaggga ccgcctgctg ccaagggctc aggcacggac     1620

ccctcccctt ctagtgcacg tgacaaggtt gtggtgactg gtgccatgat gtttgacagt     1680

agagctgtgt gagagggaga gcagctcccc tcgccccgcc cctgcagtgt gaatgtgtga     1740

aacatcccct caggctgaag ccccccaccc ccaccagaga cacactggga accgtcagag     1800

tcagctcctt ccccctcgca atgcactgaa aggcccggcc gactgctgct cgccgatccg     1860

tggggccccc tgtgcccgcc acacgcacgc acacactctt acacgagagc acactcgatc     1920

cccctaggcc agcggggaca ccccagccac acagggaggc atccttgggg cttggcccca     1980

ggcagggcaa ccccggggcg ctgcttggca ccttagcaga ctgctggaac cttttggcca     2040

gtaggtcgtg cccgcctggt gccttctggc ctgtggcctc cctgcccatg ttcacctggc     2100

tgctgtgggt accagtgcag gtcccggttt tcaggcacct gctcagctgc ccgtctctgg     2160

cctgggcccc tgccccttcc accctgtgct tagaaagtcg aagtgcttgg ttctaaatgt     2220

ctaaacagag aagagatcct tgacttctgt tcctctctct cctgcagatg caagagctcc     2280

tgggcagggg tgcctgggcc ccagggtgtg gcaggagacc cagtggatgg ggccagctgg     2340

cctgccctga tcctctgctt cctcctcaca accccaagag cccccagccc ggtccatcca     2400

cgtctggagt ctggggagag gagcagggtc ttaggactct cagctctgag catccctggc     2460

agggtcttca acctctaatc tcttccctta agccctgtgg ccacacagcc aggagagact     2520

tgccgctggc tcccgcctca tttcagccca gggtgctcat ccaggggccc agaacagtcc     2580

cacctgtgct gctgtgccca cagcacaaag ccaggcttca ctcccaaaag tgcagccagg     2640

ccctggaggg tgatcctgcc agcagcccta cagctccaca ccctacccac ccatcggcag     2700

cccctctgct gttccccagg gacctctcat acactggcca ggaggctgca gaacgtgtgt     2760

ctccccctcc ctccaagagg tcctgctccc tctgccagaa ccgtgtgtgg gcgggtggga     2820

gggcgctcgg ggcccggccc ctccctctcc ctgctggttt tagttggtcc ctatgttgga     2880

agtaaaaagt gaagcacttt attttggttg tgtttgctca cgttctgctt ggaagtgggg     2940

acccctcact gcgtccacgt gtctgcgacc tgtgtggagt gtcaccgcgt gtacatactg     3000

taaattattt attaatggct aaatgcaagt aaagtttggt ttttttgtta ttttctttta     3060


<210>  2291
<211>  4777
<212>  DNA
<213>  homo sapiens

<400>  2291
agaggccagg ccatcatcta agtgggaata aagggctaaa gctattggca ttggcagctg       60

tctccaggcg tcgtccgcgg agcctgaccc tgcgccagga cggaggaggc tgtgcccatg      120

taactgtcct gaagtactgc ggtggccccc tcccccgcgg ctgggagggc aggcaggacg      180

aggttggctt tcctcgcacg gtctctgggc gtgggccccc gccgcagctc cgcggagcct      240

cggtgtctcc tgcaacaggg ggcgggggga acagcggcga gcagccctgg gctgcggctt      300

cctccccacg cccgagtctc ctgcgcaccg ccgccgagga cgcgcgcccg agcctagtcc      360

ccacgccgcg gcgcgcccgg gctccctgct gatcccagaa caatcaacca tgacgaccga      420

atctggatca gactcggaat ccaagccgga ccaggaggcc gagccccagg aggcggcggg      480

ggcgcagggg cgcgcggggg cgcccgtgcc ggagccgccc aaggaggagc agcagcaggc      540

cctggagcag ttcgccgccg ctgcagcgca cagcaccccg gtgcggaggg aggtcactga      600

caaggaacag gagtttgctg ccagggctgc aaaacagctc gaatatcagc aattagaaga      660

cgataaactt tctcagaaat catctagcag taaactctct cggtctccat taaagattgt      720

caaaaagcct aaaagcatgc agtgcaaagt gatacttctc gatggatcag aatatacctg      780

tgatgtagag aaacgctcca gaggacaagt gctgtttgat aaagtgtgtg aacacttgaa      840

cttgctagag aaagactact ttgggcttac gtatcgagat gctgaaaacc agaagaattg      900

gttggaccct gctaaggaaa taaaaaaaca ggttcgaagt ggtgcttggc acttttcatt      960

taatgtgaaa ttttatccac cagaccctgc ccaactatct gaagatatca ccaggtacta     1020

cctctgcttg cagttgcgag atgacatcgt gtccggaagg ctgccctgct cctttgttac     1080

cctggccttg ctgggctcct acactgtcca gtcagagctc ggagactatg acccagatga     1140

atgtgggagc gattacatta gtgagttccg ctttgcacca aaccacacta aagaactgga     1200

agacaaagtg atcgagctgc acaagagcca cagaggaatg acgccagcag aagcagagat     1260

gcatttcttg gaaaatgcca aaaaattatc aatgtatggg gtagatttac atcatgctaa     1320

ggactcagaa ggggtagaaa ttatgttagg agtttgtgca agtggtctgt tgatatatcg     1380

cgaccggctg cgaataaaca gatttgcctg gcccaaggtt ctaaagattt catacaaacg     1440

gaacaacttt tacattaaga tccggccggg agagtttgaa caatttgaaa gcaccattgg     1500

gtttaagctg ccaaaccatc gagctgccaa gcgtttatgg aaagtatgtg ttgagcatca     1560

tacatttttc agactactgt taccagaagc acctcccaag aaattcctaa ccttgggttc     1620

caagtttcgt tatagtggca ggacacaagc gcaaacgaga agagccagtg cgttgataga     1680

tcgcccagca ccttactttg aacgctcatc cagcaaacgt tataccatgt ctcgcagctt     1740

ggatggagag gttggtactg gccagtacgc cacaacaaaa ggcatctctc agaccaactt     1800

gatcaccact gtgactccgg agaagaaggc tgaggaggag cgggacgagg aagaggacaa     1860

acggaggaag ggggaagaag tcacgcccat ctcggccatc cggcacgagg gaaagtcacc     1920

tgggcttggc actgactcat gtcccttgtc acccccatcc acccattgtg cccccacatc     1980

tcccacagag ctccgtagga ggtgtaagga gaatgactgc aaactgccag gttatgagcc     2040

gtccagagct gagcacctgc ctggagagcc cgccttggac tctgatggcc cagggaggcc     2100

ttacctaggg gatcaagatg tggcttttag ctacagacag caaactggca aggggaccac     2160

cctgttctcc ttctccttgc agctccctga gtcattcccc tccctcctag atgatgatgg     2220

atacctctct ttccccaacc tttctgaaac caacctcctg ccccagagct tgcagcatta     2280

cctcccgatc cgctcaccgt cccttgtgcc ctgtttcctc ttcatctttt tctttctgct     2340

gtctgcctcc ttctcagtgc catacgctct cactctctcc ttccctctgg ctctgtgcct     2400

ctgctacctg gagcccaagg cggcctcctt gagcgcctcc ctagacaatg acccgagtga     2460

cagttcagag gaagagactg acagtgagcg cacggacacc gcagccgacg gggagaccac     2520

tgccactgag tcggaccagg aggaagatgc agagctcaag gcacaggagc tagaaaaaac     2580

tcaagatgac ctgatgaaac atcaaaccaa cattagcgag ctgaaaagaa ccttcttaga     2640

aacctcaaca gacactgccg taacgaatga atgggagaag aggctttcca cctcccccgt     2700

gcgactggcc gccaggcagg aggatgcccc catgatcgaa ccacttgtcc ctgaagagac     2760

taagcagtct tctggggaaa agctcatgga tggctctgaa atcttcagtt tattagagtc     2820

tgcgcgaaaa ccaacagaat tcataggagg ggttacttct acttctcaaa gctgggttca     2880

gaaaatggaa accaagacgg agtccagtgg aatagagacg gaacccaccg tgcaccacct     2940

gccgcttagc actgagaagg tggtgcagga gaccgtgttg gtggaggagc ggcgtgtggt     3000

gcacgcgagt ggggatgctt cttactcggc gggagacagc ggggatgctg cagcacagcc     3060

cgcattcaca ggcattaaag ggaaagaggg ctctgccttg acggaggggg ctaaagagga     3120

aggaggggag gaggtcgcta aagctgtcct ggaacaggaa gagacagccg ctgcttcccg     3180

tgagcgacaa gaggagcaga gtgcagccat ccacatttca gaaactttgg aacaaaaacc     3240

tcattttgag tcctcaacgg tgaagacgga aaccatcagt tttggcagtg tttcaccggg     3300

aggagtaaag ctagaaattt ccacgaagga agtgccagta gttcacaccg aaaccaaaac     3360

catcacatat gaatcatcac aggtcgatcc aggcacagat ctggagccag gcgtgctgat     3420

gagtgcacag acgatcacat ctgaaaccac cagtaccacc accactacgc acatcaccaa     3480

aactgtgaaa gggggcattt cagagacaag aattgagaag cgaatagtca tcacggggga     3540

tgcagacatt gaccatgacc aggcgctggc tcaggcaatt aaagaggcca aagagcagca     3600

ccctgacatg tcagtgacca aagtagtggt ccataaagag acagagatca caccagaaga     3660

tggagaggat tgaccagagg aataacttag cttgcacatg aatgcagtca tgcaaaccgt     3720

taggaaaacc agagcctata tggagttccc tcttctaacc caactgactt gtatctgtcc     3780

gtggaaaatt tcagtccaga agaattgacc ttgaccatta ataaagacac tggcagagag     3840

atcttcccat aataaagcaa tctgattcag catcactaaa ccgataatgc atgaagcaac     3900

gataaaatta caaaagagca gcatttttaa ttttcacaaa atgtctcagt tttcagctat     3960

acctgcacgt tcataaccaa caatataaac cgtggtctca tgtaacacat aaacaattca     4020

tgcctttcat agtttattat tattaaagtc taaacaaaat tgcaatttct taggtaacct     4080

tatatttaca ataaatgaag attaccctca aatgctagaa gctgtctagg tccgtccggt     4140

gtgtcagatt ttcctcagat tagatgtgcc aataaccaag tttattcagt aaacaacttg     4200

tacttgtttc atctggtttt attactctca cccataaaca gtaatgactc tctgaccctc     4260

tggaaatatg taatgcttcc aatcttgctt tgtgtatctc atttaatttg ttataaggta     4320

gtactgattt tagcatatta atgcgatttc ttccttgttg tttgctttgg tctgtgttca     4380

atccagagag cttaaattgt cattattttg ggaagaaaac ctgtattttt gttagtttac     4440

aatattatga aatttcactt caggagaaac tgctgggctt cctgtggctt tgttttctta     4500

gttacttttt ccgtgccgtg tattttttaa ttgatttttc ttcttttact tgaaaagaaa     4560

gtgttttatt ttcaaatctg gtccatattt acattctagt tcagagccaa gccttaaact     4620

gtacagaatt tccactgtaa ttaaaactat ttagtgttag ttataaatag ccttcaaaaa     4680

gagagattct ccattacacg atcacctgca tcacagccca tggtgaatgt atgtttctgc     4740

atagcgaaat aaaaatggca aatgcactga aagctct                              4777


<210>  2292
<211>  4777
<212>  DNA
<213>  homo sapiens

<400>  2292
agaggccagg ccatcatcta agtgggaata aagggctaaa gctattggca ttggcagctg       60

tctccaggcg tcgtccgcgg agcctgaccc tgcgccagga cggaggaggc tgtgcccatg      120

taactgtcct gaagtactgc ggtggccccc tcccccgcgg ctgggagggc aggcaggacg      180

aggttggctt tcctcgcacg gtctctgggc gtgggccccc gccgcagctc cgcggagcct      240

cggtgtctcc tgcaacaggg ggcgggggga acagcggcga gcagccctgg gctgcggctt      300

cctccccacg cccgagtctc ctgcgcaccg ccgccgagga cgcgcgcccg agcctagtcc      360

ccacgccgcg gcgcgcccgg gctccctgct gatcccagaa caatcaacca tgacgaccga      420

atctggatca gactcggaat ccaagccgga ccaggaggcc gagccccagg aggcggcggg      480

ggcgcagggg cgcgcggggg cgcccgtgcc ggagccgccc aaggaggagc agcagcaggc      540

cctggagcag ttcgccgccg ctgcagcgca cagcaccccg gtgcggaggg aggtcactga      600

caaggaacag gagtttgctg ccagggctgc aaaacagctc gaatatcagc aattagaaga      660

cgataaactt tctcagaaat catctagcag taaactctct cggtctccat taaagattgt      720

caaaaagcct aaaagcatgc agtgcaaagt gatacttctc gatggatcag aatatacctg      780

tgatgtagag aaacgctcca gaggacaagt gctgtttgat aaagtgtgtg aacacttgaa      840

cttgctagag aaagactact ttgggcttac gtatcgagat gctgaaaacc agaagaattg      900

gttggaccct gctaaggaaa taaaaaaaca ggttcgaagt ggtgcttggc acttttcatt      960

taatgtgaaa ttttatccac cagaccctgc ccaactatct gaagatatca ccaggtacta     1020

cctctgcttg cagttgcgag atgacatcgt gtccggaagg ctgccctgct cctttgttac     1080

cctggccttg ctgggctcct acactgtcca gtcagagctc ggagactatg acccagatga     1140

atgtgggagc gattacatta gtgagttccg ctttgcacca aaccacacta aagaactgga     1200

agacaaagtg atcgagctgc acaagagcca cagaggaatg acgccagcag aagcagagat     1260

gcatttcttg gaaaatgcca aaaaattatc aatgtatggg gtagatttac atcatgctaa     1320

ggactcagaa ggggtagaaa ttatgttagg agtttgtgca agtggtctgt tgatatatcg     1380

cgaccggctg cgaataaaca gatttgcctg gcccaaggtt ctaaagattt catacaaacg     1440

gaacaacttt tacattaaga tccggccggg agagtttgaa caatttgaaa gcaccattgg     1500

gtttaagctg ccaaaccatc gagctgccaa gcgtttatgg aaagtatgtg ttgagcatca     1560

tacatttttc agactactgt taccagaagc acctcccaag aaattcctaa ccttgggttc     1620

caagtttcgt tatagtggca ggacacaagc gcaaacgaga agagccagtg cgttgataga     1680

tcgcccagca ccttactttg aacgctcatc cagcaaacgt tataccatgt ctcgcagctt     1740

ggatggagag gttggtactg gccagtacgc cacaacaaaa ggcatctctc agaccaactt     1800

gatcaccact gtgactccgg agaagaaggc tgaggaggag cgggacgagg aagaggacaa     1860

acggaggaag ggggaagaag tcacgcccat ctcggccatc cggcacgagg gaaagtcacc     1920

tgggcttggc actgactcat gtcccttgtc acccccatcc acccattgtg cccccacatc     1980

tcccacagag ctccgtagga ggtgtaagga gaatgactgc aaactgccag gttatgagcc     2040

gtccagagct gagcacctgc ctggagagcc cgccttggac tctgatggcc cagggaggcc     2100

ttacctaggg gatcaagatg tggcttttag ctacagacag caaactggca aggggaccac     2160

cctgttctcc ttctccttgc agctccctga gtcattcccc tccctcctag atgatgatgg     2220

atacctctct ttccccaacc tttctgaaac caacctcctg ccccagagct tgcagcatta     2280

cctcccgatc cgctcaccgt cccttgtgcc ctgtttcctc ttcatctttt tctttctgct     2340

gtctgcctcc ttctcagtgc catacgctct cactctctcc ttccctctgg ctctgtgcct     2400

ctgctacctg gagcccaagg cggcctcctt gagcgcctcc ctagacaatg acccgagtga     2460

cagttcagag gaagagactg acagtgagcg cacggacacc gcagccgacg gggagaccac     2520

tgccactgag tcggaccagg aggaagatgc agagctcaag gcacaggagc tagaaaaaac     2580

tcaagatgac ctgatgaaac atcaaaccaa cattagcgag ctgaaaagaa ccttcttaga     2640

aacctcaaca gacactgccg taacgaatga atgggagaag aggctttcca cctcccccgt     2700

gcgactggcc gccaggcagg aggatgcccc catgatcgaa ccacttgtcc ctgaagagac     2760

taagcagtct tctggggaaa agctcatgga tggctctgaa atcttcagtt tattagagtc     2820

tgcgcgaaaa ccaacagaat tcataggagg ggttacttct acttctcaaa gctgggttca     2880

gaaaatggaa accaagacgg agtccagtgg aatagagacg gaacccaccg tgcaccacct     2940

gccgcttagc actgagaagg tggtgcagga gaccgtgttg gtggaggagc ggcgtgtggt     3000

gcacgcgagt ggggatgctt cttactcggc gggagacagc ggggatgctg cagcacagcc     3060

cgcattcaca ggcattaaag ggaaagaggg ctctgccttg acggaggggg ctaaagagga     3120

aggaggggag gaggtcgcta aagctgtcct ggaacaggaa gagacagccg ctgcttcccg     3180

tgagcgacaa gaggagcaga gtgcagccat ccacatttca gaaactttgg aacaaaaacc     3240

tcattttgag tcctcaacgg tgaagacgga aaccatcagt tttggcagtg tttcaccggg     3300

aggagtaaag ctagaaattt ccacgaagga agtgccagta gttcacaccg aaaccaaaac     3360

catcacatat gaatcatcac aggtcgatcc aggcacagat ctggagccag gcgtgctgat     3420

gagtgcacag acgatcacat ctgaaaccac cagtaccacc accactacgc acatcaccaa     3480

aactgtgaaa gggggcattt cagagacaag aattgagaag cgaatagtca tcacggggga     3540

tgcagacatt gaccatgacc aggcgctggc tcaggcaatt aaagaggcca aagagcagca     3600

ccctgacatg tcagtgacca aagtagtggt ccataaagag acagagatca caccagaaga     3660

tggagaggat tgaccagagg aataacttag cttgcacatg aatgcagtca tgcaaaccgt     3720

taggaaaacc agagcctata tggagttccc tcttctaacc caactgactt gtatctgtcc     3780

gtggaaaatt tcagtccaga agaattgacc ttgaccatta ataaagacac tggcagagag     3840

atcttcccat aataaagcaa tctgattcag catcactaaa ccgataatgc atgaagcaac     3900

gataaaatta caaaagagca gcatttttaa ttttcacaaa atgtctcagt tttcagctat     3960

acctgcacgt tcataaccaa caatataaac cgtggtctca tgtaacacat aaacaattca     4020

tgcctttcat agtttattat tattaaagtc taaacaaaat tgcaatttct taggtaacct     4080

tatatttaca ataaatgaag attaccctca aatgctagaa gctgtctagg tccgtccggt     4140

gtgtcagatt ttcctcagat tagatgtgcc aataaccaag tttattcagt aaacaacttg     4200

tacttgtttc atctggtttt attactctca cccataaaca gtaatgactc tctgaccctc     4260

tggaaatatg taatgcttcc aatcttgctt tgtgtatctc atttaatttg ttataaggta     4320

gtactgattt tagcatatta atgcgatttc ttccttgttg tttgctttgg tctgtgttca     4380

atccagagag cttaaattgt cattattttg ggaagaaaac ctgtattttt gttagtttac     4440

aatattatga aatttcactt caggagaaac tgctgggctt cctgtggctt tgttttctta     4500

gttacttttt ccgtgccgtg tattttttaa ttgatttttc ttcttttact tgaaaagaaa     4560

gtgttttatt ttcaaatctg gtccatattt acattctagt tcagagccaa gccttaaact     4620

gtacagaatt tccactgtaa ttaaaactat ttagtgttag ttataaatag ccttcaaaaa     4680

gagagattct ccattacacg atcacctgca tcacagccca tggtgaatgt atgtttctgc     4740

atagcgaaat aaaaatggca aatgcactga aagctct                              4777


<210>  2293
<211>  5945
<212>  DNA
<213>  homo sapiens

<400>  2293
aaacagcccc caccctggaa gcctcaggtg ccttccttcc tccccttggt ggggtgagga       60

cgaccgggat gagtcgtctg agaagcactt tgagggggga ggagctgaag gccacacctg      120

gaagggcgat ttattccttg ggcgctgcca ggtgtctgcc gccttcaccc agaaaccgat      180

gatgttcgga gccaggcttc ttcaaagtct cacagccagc ctaccctcaa agcctgagtg      240

attgtggaag gagccagcgt tcactcagca gaggaacaga gctttcctgc cgcaggctct      300

cagtgaagat ccagggagca gaggcgtggg caaggagcac tgggctcaga tgcaggagaa      360

ccggtttgaa ccctagcact accgcctcta cactgaggaa ccttggggat tactcagccc      420

cctggaacct aatttccaag tgggatcttg tgtgtgataa tgcctggaag gtccatatcg      480

ctaagttctc cttactggtt ggattaatct ttggctacct aataactgga tgcattgctg      540

actgggtcgg ccggcggcct gtgctgctgt tttccatcat cttcattctg atctttggac      600

tgactgtggc actgtcagtg aatgtgacaa tgttcagcac actcaggttc tttgaaggat      660

tttgcctggc tggaatcatt ctcaccttgt atgctttacg aatagagctg tgcccccctg      720

gaaaacggtt catgattacg atggtggcga gcttcgtggc catggcgggc cagttcctca      780

tgcctgggct agccgccctg tgccgggatt ggcaggtgct gcaggccctc atcatctgcc      840

ccttcctgct catgctgctc tactggtcga tattccccga gtccctccgg tggctaatgg      900

ccacccagca gtttgagtct gcaaagaggc tgatcctcca cttcacacag aagaatcgca      960

tgaaccctga gggcgacatc aagggtgtga taccagagct ggagaaagag ctttcccgga     1020

ggcccaagaa ggtctgcatc gtgaaggtgg tggggacacg gaacctgtgg aagaacattg     1080

tggtcctgtg tgtgaactcg ctgacggggt acgggatcca ccactgcttt gccaggagca     1140

tgatgggcca cgaggtgaag gtgccgctcc tggagaactt ctatgctgac tactatacca     1200

cggccagcat cgcgctggtg tcctgcctgg ccatgtgcgt ggtggtccga ttcctcgggc     1260

gcaggggagg gctgctgctc ttcatgatcc tcaccgccct ggcctcactc ctgcagctcg     1320

gcctcctcaa cctgattgga aagtacagcc agcacccaga ctcagggatg agtgacagcg     1380

tcaaggacaa attttccatc gcgttttcca tcgtgggcat gtttgcctcc catgcggtgg     1440

ggagcctcag cgtgttcttc tgtgcggaga tcaccccgac ggtgataagg tgtggcgggc     1500

tggggctggt gctggccagc gcgggcttcg gcatgctgac ggcacccatc atcgagctgc     1560

acaaccagaa aggctacttc ctgcaccaca tcatctttgc ctgctgcacg ctcatctgca     1620

tcatctgcat cctcctgctg cccgagagca gggaccagaa cctgcctgag aacatttcta     1680

acggggagca ctacacgcgc cagccgctgc tgccgcacaa gaagggggag cagccactgc     1740

tgctcaccaa cgccgagctc aaggactact cgggcctcca cgatgccgca gccgcgggtg     1800

acacactgcc cgagggtgcc acggccaacg gcatgaaggc catgtagccc ggcctgcgga     1860

acccggggct ccagggtctg gggcagcttg ggcacaggtt tacagaccag ggaccgaaca     1920

cgcagccagg ggtgggaaag ctgcctcagc caagctgagc ctctcaactg gtgtggggaa     1980

atcctgtctt tccaaaagtc caaggagcgc gggtcggagg agacaaactc tttggaaata     2040

accctttcaa gactttcttt tctgccgtta aatgtgtgta tttattttgg tcatttttac     2100

gagaagcact ttattccctc tccctctcac tgatcacaaa tggaatcacc tccctgggca     2160

gcgagacgca gttgctctgg gaagatgcca cagtgaccag ggccatggcc ggtccctctg     2220

gggagatggg acacggctcc tggcagcacc caggagcccc ccaggctgcc tgcctgcgtg     2280

cagaggcagg agaggaccgt ggagcgtttc cgggactgca ttttagacgg agtgaaatgt     2340

acatgaattt ggcttttgct agagtctgtg tatggttttt taaggtcctt tttccctttc     2400

tgtttgtaag gtaagagctt ctgttcgtgt gcagggaaag cagctcacag acgccgttaa     2460

aaccagcttc atctttcctt caggatcatc cttttgtact tgatgctgga agctcttgga     2520

gaaaaagctt aaacatttca ccagaaatct taattgagca gcagtcatat cgccacagct     2580

ttgtgagtac acagctaaca gatgcgtcga gacctgagat gtgctcgttt ttattcctcc     2640

tctcccagat tggctccagc agaaaagtcc ctcgtgcaca ggcagctctt gtgccggcac     2700

tacttgaaaa catggctact ttctaagcta caaaccatta gaaaataact caaaaagatg     2760

gcagaggcaa atccacagaa ggggggctgc cctccacaca cacacgcccg tcacccacac     2820

cttgagcaca caccatgaag atcaccagct tggatggccg tcacctcaga catcactcca     2880

gggagcaccc gcaggagctg ggccccctca cgcctgcctt cctgggccag cttcctgctt     2940

gcagtcactc gcatagcaca gaggtggggc ttcgggcagg gagcggagat tcctcatagg     3000

tgagtccaaa tgacctccag cctctcgaag gcatcaagac aaattgaaag aaagcaataa     3060

ctcaccaaag ctcaacgctg cccctgcctc gacctccatg ggtctcttcg tgttcctcgt     3120

ttcaccccag aaagtggagg tttcctcttg gcattttcgg aggaaacttg taggacaccc     3180

aaggcgacta agagacagcc tccttggcaa gggcaggcac cactttgtag caacttgggc     3240

accagctttt ctggacagcc tggcttctta ctggcattgt ccaactcatc ccttctcgaa     3300

gcatgtcttt gccatgggct gtgtccttcc agggaaattg tggtctcggg cctgggtgag     3360

acaatgaagt gacttccaac cgacagttgc tagaattcac agggcagaaa aggggttgac     3420

cttctcccct tctggctttc cacccggcct gctgcttgct gtcgccactc atgtctcctc     3480

cacatgcggt ccacacatca gtaagggcct ggagatgtgt aaagacacag caaggggcaa     3540

gcagactctt ggccacgtgt ttccagtggc tggaccacgc cgacacctgg gatcttgaga     3600

tacccaggaa gggaggctgt ctggccagcc tctccctgcc tccacttgct ccacgtccag     3660

ctcctcacct tccctctttt ttaaagtcac atttccatgt ttcaacatta gtttgcattc     3720

acctttacaa aggcctttct ttagatctgt gcagcctttg cgtgccaaac ttgtgaaatt     3780

ccttttacct tttttggagt acttgctata aagccacctg tcaacaaacc cccattatgt     3840

acagaatagg acctatccag tagccaggcc agtaggcagt tggggaaggt gggaaggatc     3900

cagcgaggcc cctgagcctg cacctggaca ggtgtacgtc tgcacccatc accctcagca     3960

ccaggccacc ctgcagtcca cttactgtac tgtgttgtgg aaggatatgc taagtgatga     4020

aagttgcgag cagtctcact ggtcgtgtaa actttttttt ttttttggaa attgaagctg     4080

tagagtgctg cccgaaatct ctaggaagtt ggtggcaagg gacagcactc acactcttct     4140

ggtcatgatc tctgatctcc acctcaaatg acaataaaaa actggtccaa cgaagacact     4200

gctcagcact tcagccatca ggactaatcc atcgatgact ggaaaagagg ctagctttga     4260

ggaaaacagc ctgggctctt gggagcagag tccagtgggt gtgaggctga cttgccgacg     4320

gtcggcaggt aatggctctc agccggcgag gcggtcccac agctctcctc ccagggcagc     4380

ctgaggagga ggaggccggg tgcctgtttg gtggcagctt cagcctaggg atacctgaag     4440

ctgttgagca acacctttat gaaatgttgc cagagcagca acacttccct gtgggcacag     4500

ccccgggaaa tccggtacca agtgagcaag gtggcaggac ccacccaagc ctgatacgca     4560

tctgggcccg ccgggctcag caggggaggc tgctacggct gcccacttcc cagcaccgtc     4620

tgtcacgctt gaacccctct gtgctgttcc cttcctggct aatagggaga cccttcgcag     4680

gcacccactg tttcaacttg accctcccac cccctgctac tctcctccac acacccctcc     4740

gttccgctag cctaccctgt cagcctttca ataaaagtta tgcacaaatg tgaacacctg     4800

agatggagct gaacatttct tcactttgtt ctttttctga agtcaaactc ttatcaaatg     4860

ccctaaaatt attaccaccc aagagaaaca ggaaaaaggt tacatgtttt tgtttactga     4920

gagtaagatc acctgcatct ggaagacggg ctggtaaatt ggtttggcta cagaacagaa     4980

agaaaacaaa aacaaacctc gtaagggaag tatcacactc agacaccacc gcttcctaga     5040

gccaaatgag caatcccaaa ctgcaagtgc cataagtggg cctgtgaggt cacaccgccc     5100

ggcccgaggt atcgcatgtg cgggggaggt ccacactaca gctgtcctct cgtctagaag     5160

gcaccacctc gctttcatgt cccgtgtgtt ttggaaaagc agtatggtgt gtcatgtcta     5220

gcggcgaaca cttccctccc tgtccttgag gttgtaatat aaaaactgtg tttctgtacg     5280

tgtgggtggg aattctctga cggtgctcgt tcatagcaca agcttacgct gagttctgaa     5340

ctgtcgttca cagctgcgtg tctgcatggt gtcgcatctg ttgtaccttt ggggaaaatt     5400

tgtatgtaaa tgtacagaaa taaaaacgtt gccccattaa cagatttcct ctggaatgtc     5460

ttccctacct cacctgatgg tatccaccga agggcatttc actaccatta atggtgagta     5520

ataaaatcct ccgtgttcat tcagacctca ctgcgtcact actttgaacg cctctgtaag     5580

ctgtgtcttc actcgccccg aggtgggtgg agggaggcct ctcactctgc ttcgagtcct     5640

ggtcttaaag gtagtcagag gcagaggctg gattaaacac acactgttta ccaagtgcca     5700

ctctcagacc acctgagaga cgggggccat cagtaaaatt aagaggaatt tttttccctt     5760

gttcgtgtat gttctgctga tccgtggcct gaaggttcct agagacgtca agaaatgaat     5820

atcttacact gtgattctgt gaggaaagac tggtaaccca aaactctctt ctctaatgta     5880

ttttttaacg aaaatgacaa tatttcttta ataaagtatt tataccaaaa aaaaaaaaaa     5940

aaaaa                                                                 5945


<210>  2294
<211>  1983
<212>  DNA
<213>  homo sapiens

<400>  2294
aggaaagaaa gaaagcgagg gagggaaaga ggaggaagga agatgcgaga aggcagagga       60

ggagggaggg agggaaggag cgcggagccc ggcccggaag ctaggtgagt gtggcatccg      120

agctgaggga cgcgagcctg agacgccgct gctgctccgg ctgagtatct agcttgtctc      180

cccgatggga ttcccgtcca agctatctcg agcctgcagc gccacagtcc ccggccctcg      240

cccaggttca ctgcaaccgt tcagaggtcc ccaggagctg ctgctggcga gcccgctact      300

gcagggacct atggagccat tccgtagtgc catcccgagc aacgcactgc tgcagcttcc      360

ctgagccttt ccagcaagtt tgttcaagat tggctgtcaa gaatcatgga ctgttattat      420

atgccttgtt ttctgtcaag acaccatgat tcctggtaac cgaatgctga tggtcgtttt      480

attatgccaa gtcctgctag gaggcgcgag ccatgctagt ttgatacctg agacggggaa      540

gaaaaaagtc gccgagattc agggccacgc gggaggacgc cgctcagggc agagccatga      600

gctcctgcgg gacttcgagg cgacacttct gcagatgttt gggctgcgcc gccgcccgca      660

gcctagcaag agtgccgtca ttccggacta catgcgggat ctttaccggc ttcagtctgg      720

ggaggaggag gaagagcaga tccacagcac tggtcttgag tatcctgagc gcccggccag      780

ccgggccaac accgtgagga gcttccacca cgaagaacat ctggagaaca tcccagggac      840

cagtgaaaac tctgcttttc gtttcctctt taacctcagc agcatccctg agaacgaggt      900

gatctcctct gcagagcttc ggctcttccg ggagcaggtg gaccagggcc ctgattggga      960

aaggggcttc caccgtataa acatttatga ggttatgaag cccccagcag aagtggtgcc     1020

tgggcacctc atcacacgac tactggacac gagactggtc caccacaatg tgacacggtg     1080

ggaaactttt gatgtgagcc ctgcggtcct tcgctggacc cgggagaagc agccaaacta     1140

tgggctagcc attgaggtga ctcacctcca tcagactcgg acccaccagg gccagcatgt     1200

caggattagc cgatcgttac ctcaagggag tgggaattgg gcccagctcc ggcccctcct     1260

ggtcaccttt ggccatgatg gccggggcca tgccttgacc cgacgccgga gggccaagcg     1320

tagccctaag catcactcac agcgggccag gaagaagaat aagaactgcc ggcgccactc     1380

gctctatgtg gacttcagcg atgtgggctg gaatgactgg attgtggccc caccaggcta     1440

ccaggccttc tactgccatg gggactgccc ctttccactg gctgaccacc tcaactcaac     1500

caaccatgcc attgtgcaga ccctggtcaa ttctgtcaat tccagtatcc ccaaagcctg     1560

ttgtgtgccc actgaactga gtgccatctc catgctgtac ctggatgagt atgataaggt     1620

ggtactgaaa aattatcagg agatggtagt agagggatgt gggtgccgct gagatcaggc     1680

agtccttgag gatagacaga tatacacacc acacacacac accacataca ccacacacac     1740

acgttcccat ccactcaccc acacactaca cagactgctt ccttatagct ggacttttat     1800

ttaaaaaaaa aaaaaaaaaa ggaaaaaatc cctaaacatt caccttgacc ttatttatga     1860

ctttacgtgc aaatgttttg accatattga tcatatattt tgacaaaata tatttataac     1920

tacgtattaa aagaaaaaaa taaaatgagt cattatttta aaggtaaaaa aaaaaaaaaa     1980

aaa                                                                   1983


<210>  2295
<211>  954
<212>  DNA
<213>  homo sapiens

<400>  2295
agacgttctt cgccgagagt ggtcggggtt tcctgcttca acagtgcttg gacggaaccc       60

ggcgctcgtc ctgcaccccg gccggccgcc catagccagc cctccgtcac ctcttcacca      120

tgccctcgga ctgccccaag gcccccgccg cagctccagc gccgcgtagc caccactgcc      180

gctgccgccg cctctcctta gtcgccggca tgacgaccgc gtctacctcg caggtgcgcc      240

agaactacca ccaagactca gaggccgcca tcaaccgcca gatcaacctg gagctctacg      300

cctcctccat ttacctgtgc gtggcttact actttgacag cgatgatgtg gctttgaaga      360

actttgccaa atactttctt caccaatctc atgaggagag ggaacatgct gagaaattga      420

tgaagctgta gaaccaacga ggtggccgaa tcttccttca ggatatcaag aaaccagact      480

gtgcggggag aatgcgatgg gagagcgggc tgaatgcgat ggattacatt tggaaaaaat      540

tgtgcatttt gcattacatt tggaaaaaaa tgtgaatcag tcactactgg aactgcacaa      600

actggccact gacaaaaatg acccccattt gtgtgacttc attgagacac attacctgaa      660

tgaacaagtg aaggccatca aagaattggg tgaccacgtg accaacatgc acgagatggg      720

agcgcccgaa tctggcgtgg cagaatacct ctttgacaag cacaccctgg gagacagtga      780

taatgaaagc taagcctcag gctaatttcc ccatagccat agggtgactt accttgtcac      840

caaggcagcg catgtatgtt ggggtttcct ttaccttttc tataagttgt tccaagacac      900

ccacttaagt tctttgattt gtaccattcc ttcaaataaa taaatttggt accc            954


<210>  2296
<211>  5529
<212>  DNA
<213>  homo sapiens

<400>  2296
gatttgggag ttgggaggtg agatgattgg agtgaagaga gttaatgtca tggaaaggaa       60

aagctgtctg aagaaaaata cacattttaa tgtccctctt cagccgtgcc tgctgagagc      120

tctcctggga tgataagtga aagtgtttgg attttttttt aagttttaaa actctgccaa      180

agcattgctc agtgtatctg ggcagcccct tccggcaaaa cgcagcagta gcagaggcag      240

cttctgagag cctgggcagg cagcagctgg ctgaccaagt ccactggaag agaaggcttg      300

tgccagccgg gagaaggaag ccggggacag gatgaaagca acaacacctt tgcagacagt      360

cgaccggccc aaggactggt acaagacgat gtttaagcaa attcacatgg tgcacaagcc      420

gggtctgtac aacccaccct acagtgctca gtcacaccct gctgcaaaga cccaaaccta      480

cagacctctt tccaaaagcc actccgacaa cagccccaat gcctttaagg atgcgtcctc      540

cccagtgcct cccccacatg ttccacctcc agtcccgccg cttcgaccaa gagatcggtc      600

ttcaacagaa aagcatgact gggatcctcc agacagaaaa gtggacacaa gaaaatttcg      660

gtctgagcca aggagtattt ttgaatatga acctggcaag tcatcaattc ttcagcatga      720

aagaccagcc tccttgtatc agtcctctat agacagaagc ctggaaagac ccatgagttc      780

tgcaagcatg gccagtgact tcaggaagcg gaggaagagc gagcctgcag tgggtccacc      840

acggggcttg ggagatcaaa gtgcgagcag gactagccca ggccgagtgg acctcccagg      900

atcaagcacc actcttacaa agtctttcac tagctcttct ccttcttccc catcaagagc      960

aaaaggtggg gatgatagca aaatatgtcc atccctttgc agttactcag ggctcaacgg     1020

caacccctcc agtgagttag attactgtag cacttacaga cagcacttgg atgtccctcg     1080

ggactcacca agagccatta gtttcaagaa cggctggcaa atggcccggc aaaacgcaga     1140

aatctggagc agcacggaag aaaccgtctc tcccaaaatc aaatcccgga gctgtgacga     1200

tctcctaaac gacgactgcg atagcttccc ggacccgaaa gtcaagtcgg aaagcatggg     1260

ctccctgtta tgtgaggagg actccaagga gagctgcccc atggcgtggg ggtcccccta     1320

cgtcccggag gttcgcagta acggcagatc aaggatcaga cacaggtcag cccgcaacgc     1380

cccggggttc ctgaagatgt acaagaaaat gcaccgcatc aaccgcaagg acctgatgaa     1440

ctccgaggtg atctgctccg tgaagtccag gattctgcag tacgagagcg agcagcagca     1500

caaggacctg ctgcgcgcct ggagccagtg ctccacggag gaggtgcccc gggacatggt     1560

gcccacacgc atctccgaat tcgaaaagct gatccagaag tccaaatcca tgccaaattt     1620

aggggatgac atgctgtctc ccgtaaccct agaaccaccg caaaatggcc tatgtcccaa     1680

gaggcggttt tccattgagt atttgctgga ggaagaaaat caaagcggcc cccccgctcg     1740

gggccggcga ggctgccagt ctaacgccct ggtgcccatt cacattgaag tcaccagcga     1800

tgagcagccc cgagcacacg tggagttttc cgacagcgac caggacgggg ttgtgtccga     1860

ccacagtgac tacattcacc tagaggggtc atccttctgc agtgaaagtg actttgatca     1920

cttttccttc acatcctccg aaagctttta cggatccagc caccaccacc accatcacca     1980

ccaccaccac caccgccacc tcatcagctc ctgcaaaggc aggtgcccgg cctcctacac     2040

tcgatttacc acaatgttaa aacacgaaag agccagacac gaaaacaccg aggagcccag     2100

aaggcaagaa atggaccctg gcctttctaa acttgctttt ctagtcagtc ctgtgccttt     2160

ccggaggaaa aaaaattcgg ctcctaagaa acagactgaa aaggcaaaat gtaaagcatc     2220

tgtgtttgag gctctggact ctgcccttaa agacatctgt gaccaaatta aagctgaaaa     2280

gaaaaggggg agcttgccgg acaacagcat cctgcaccgc ctcatcagtg agctgctgcc     2340

agatgttccc gagaggaact catccctgag agcgctgagg aggagccccc tgcaccagcc     2400

tctccaccca ctgcctcccg atggtgctat tcattgtcca ccctaccaga atgactgcgg     2460

gagaatgccc cgcagtgcct ctttccaaga cgtggacaca gccaacagca gctgccacca     2520

ccaagaccgt ggcggtgcac tccaagaccg tgagtcccct agaagttact catccacttt     2580

gactgacatg gggagaagtg caccaaggga aagaagagga actccagaaa aagagaaatt     2640

gcctgcaaaa gctgtttatg attttaaggc tcagacatct aaggagttgt catttaagaa     2700

aggagatact gtctacatcc tcaggaaaat tgatcaaaat tggtatgagg gagaacacca     2760

cgggagagtg ggcatcttcc cgatctcata cgtagagaaa ctcacacctc ctgagaaagc     2820

acagcctgca agaccacctc cgccagccca gcccggagaa atcggagaag ctatagccaa     2880

atacaacttc aacgcagaca caaatgtgga gctgtcactg agaaagggag atagagttat     2940

tcttcttaaa agagttgatc aaaactggta tgaaggtaaa atcccaggaa ccaacagaca     3000

aggcatcttc cctgtttcct atgtggaggt cgtcaagaag aacacaaaag gtgctgagga     3060

ctaccctgac cctccaatac cccacagcta ttctagtgat aggattcaca gcttgagctc     3120

aaataagcca cagcgtcctg tgtttactca tgaaaatatt caaggtgggg gggaaccgtt     3180

tcaggctctg tataactata ctcccaggaa tgaagatgag ctggagctca gagaaagtga     3240

tgtcattgat gtcatggaaa agtgtgatga cggctggttt gtggggacct caagaagaac     3300

caaattcttt ggtactttcc ccggaaacta cgtcaagagg ctgtgaattg cgctccctcc     3360

ttctgtagag gccgcctgcc agccatgcac ctgcgtcaac gcgcctgaaa caccccgcgg     3420

gcctcccgtt gtcatgcctt acggtttcca atgcgccgtc accatctcca cctgccacca     3480

aaccaccagc agagtagccg ccgctgctgt gagcctgggg acgacatggc aggctggtcc     3540

ccctccgtga aagtgtggat tcctacttcc tgctctaagc tttgacacgt caaaatgtgg     3600

gatcagaaag aaaaaaatca tgatatttaa aaatggtcaa atatttgagg caaaaaaaaa     3660

aaaaaaaagt gtctccagga ggctgtccag cctcgtggct ccatttcaac atctcccccc     3720

aggcgatgtt ctcccccaag acgaccagaa aattgtttat tggggaatgc tgtggtttgc     3780

attttcatat tcttcgcttg gcagtgtgta ttcttttcac aagtttgcct agtgtcttgg     3840

tttacacaat atgacaactg taactgtact ttagctattg tttgcctgca catacatgtt     3900

gtaatatgca cagtgattac aacctttaaa gcaagaggag gcgagttaat ttggatgagt     3960

gtgattttgc tgattgaatg tgagttttca aataggagtc tttttctgca atttgtttgc     4020

attttttaga agtgcaaaca gtaagtaaat aaaagccttc ggtaataatc atgacaatac     4080

aagaggctga gctaggctac aggggaaaac tattgtgttg taaagttgca tcgctatttt     4140

atattaaaat gtaatgatca gcatcatgaa caatgagctc ttagtgtttt atttatctga     4200

aaaaatgtaa gtaaaagcag tgttagtgag aggtgcaaag aattattcta acagacacct     4260

gaaagtatct gtaagcaata ctagtaggta agatttcact gtgtgtacac atacacattt     4320

gagattgtat gagaacatat aatccatatg atatgttgta cattttatgg aaatgtaata     4380

gaatctcaca cattatttta tagaaataga gtacagaagc atcacaagta ttaaagttgg     4440

ttttagcaag gattaggatt actacaatta tttttactat aataattatt tttcttctat     4500

ggaactcaga atcctggcta catttgagga caggaatatg ttgagcctga ttttcctggt     4560

gtgtgtaaaa tatttcctag gaataaatta ggcacttttt agaagcaatg ttaaatcatt     4620

caggttttat tttctgccct gaagcagaaa tttaaaaaat gatattggga cctggaaggt     4680

ttaatatggt tcacagtgcc tgaattacac ctgctccgaa aactagcttt gtatttctta     4740

tgactttgca taagaactgt tcatctttgg atcttgagca ccttacagat aaaacttttt     4800

atggcatctc tttcatggac agtgatattg atcttttcac aatgtacgta gcctctagaa     4860

ttttgtacat atgtttgctc tttttttgta cagactagtt gttgagaaaa caggggcgtt     4920

tcctaatttg gtctttatcc tgcgacaaca ctttcagcag actagcctct ccttatctca     4980

cagatcacaa gcacccctag atagtgtgat tctgtcagat agcatttatg caaaaatcta     5040

tgaagttaaa agatcgtaga agccaaatga aatgtacata tctactgact gatgacaagg     5100

gaatttcatt aggaagaagg taaagaaaca tcgttgagta gcctaccttg atttctgtca     5160

agttcataac cagcttcata ttttaaaggc ttcaggtttg aaattaagtc aactgcatgc     5220

agctttgctg ataaatgaat aattctcttt gatgccattt atgagaaaag acttcaatat     5280

ctgttgcctg tcatatttaa gaaaaattac tgtttctact ctctgtatct gattttaaaa     5340

gaaaaaacta ttcatacctg gcttccaggt aattgacttt gaattcttac aagcaaaggt     5400

cattgtgttt ttcttgaata gacatctaat aaattttgct tggaagtata cttcagtttt     5460

tcttcttgac atttatcttt ataaaaattg tgtattttat tccaacttgt taaactaaga     5520

gaaaatgca                                                             5529


<210>  2297
<211>  3484
<212>  DNA
<213>  homo sapiens

<400>  2297
tgccctcccg cggctgcagc cggagccgaa ggtggtggct gcacagtaga cgccccctca       60

cggcttcccc cacacgctcc cgccccctcg ctcgcccatc gcgcttccct cacaggctct      120

gcagtcctcc cccacagacg ccttccccct tggactctca ttcccttttc cacggagccc      180

cgcgctttcg tgagccccct cgaggaacct ggtctccgca tccagttacc acctcctgcc      240

tcagaggcca tctgagccct tcgcacctcg cccctcagtc cccccttccc cccccgcccg      300

cgtcgcctcg ctccctcccg cccccccatc atcccttccc tcgcagttcc cctgtcctga      360

ggggagcccc gccacgggca gcgcggcggc ggcggcagga gggagaaagt gaagcggtag      420

ctcgcgcaca ctcgcgccct cactcccggc taggcggcac ccaccgccgg gaggaggagg      480

aggagccgag aggagctgag cgagcgcgga agtagctgct gctggtggtg acaatgtcaa      540

ataacggcct agacattcaa gacaaacccc cagcccctcc gatgagaaat accagcacta      600

tgattggagc cggcagcaaa gatgctggaa ccctaaacca tggttctaaa cctctgcctc      660

caaacccaga ggagaagaaa aagaaggacc gattttaccg atccatttta cctggagata      720

aaacaaataa aaagaaagag aaagagcggc cagagatttc tctcccttca gattttgaac      780

acacaattca tgtcggtttt gatgctgtca caggggagtt tacgggaatg ccagagcagt      840

gggcccgctt gcttcagaca tcaaatatca ctaagtcgga gcagaagaaa aacccgcagg      900

ctgttctgga tgtgttggag ttttacaact cgaagaagac atccaacagc cagaaataca      960

tgagctttac agataagtca gctgaggatt acaattcttc taatgccttg aatgtgaagg     1020

ctgtgtctga gactcctgca gtgccaccag tttcagaaga tgaggatgat gatgatgatg     1080

atgctacccc accaccagtg attgctccac gcccagagca cacaaaatct gtatacacac     1140

ggtctgtgat tgaaccactt cctgtcactc caactcggga cgtggctaca tctcccattt     1200

cacctactga aaataacacc actccaccag atgctttgac ccggaatact gagaagcaga     1260

agaagaagcc taaaatgtct gatgaggaga tcttggagaa attacgaagc atagtgagtg     1320

tgggcgatcc taagaagaaa tatacacggt ttgagaagat tggacaaggt gcttcaggca     1380

ccgtgtacac agcaatggat gtggccacag gacaggaggt ggccattaag cagatgaatc     1440

ttcagcagca gcccaagaaa gagctgatta ttaatgagat cctggtcatg agggaaaaca     1500

agaacccaaa cattgtgaat tacttggaca gttacctcgt gggagatgag ctgtgggttg     1560

ttatggaata cttggctgga ggctccttga cagatgtggt gacagaaact tgcatggatg     1620

aaggccaaat tgcagctgtg tgccgtgagt gtctgcaggc tctggagttc ttgcattcga     1680

accaggtcat tcacagagac atcaagagtg acaatattct gttgggaatg gatggctctg     1740

tcaagctaac tgactttgga ttctgtgcac agataacccc agagcagagc aaacggagca     1800

ccatggtagg aaccccatac tggatggcac cagaggttgt gacacgaaag gcctatgggc     1860

ccaaggttga catctggtcc ctgggcatca tggccatcga aatgattgaa ggggagcctc     1920

catacctcaa tgaaaaccct ctgagagcct tgtacctcat tgccaccaat gggaccccag     1980

aacttcagaa cccagagaag ctgtcagcta tcttccggga ctttctgaac cgctgtctcg     2040

agatggatgt ggagaagaga ggttcagcta aagagctgct acaggtgaga aaactgaggt     2100

ttcaagtgtt tagtaacttt tccatgatag ctgcatcaat tcctgaagat tgccaagccc     2160

ctctccagcc tcactccact gattgctgca gctaaggagg caacaaagaa caatcactaa     2220

aaccacactc accccagcct cattgtgcca agccttctgt gagataaatg cacatttcag     2280

aaattccaac tcctgatgcc ctcttctcct tgccttgctt ctcccatttc ctgatctagc     2340

actcctcaag actttgatcc ttggaaaccg tgtgtccagc attgaagaga actgcaactg     2400

aatgactaat cagatgatgg ccatttctaa ataaggaatt tcctcccaat tcatggatat     2460

gagggtggtt tatgattaag ggtttatata aataaatgtt tctagtcttc cgtgtgtcaa     2520

aatcctcacc tccttcataa ccatctccca caattaattc ttgactatat aaatttatgg     2580

tttgataata ttatcaattt gtaatcaatt gagatttctt tagtgcttgc ttttctgtga     2640

ctcaactgcc cagacacctc attgtacttg aaaactggaa cagcttggga atgccatggg     2700

gtttgataat ctgccaggga catgaagagg ctcagcttcc tggaccatga ctttggctca     2760

gctgatcctg acatgggaga acaaccacat ttttctttgt gtgtgcttct agcagctgtt     2820

cgggaggacc ttgacccaat agtgttccca tgctgtttct tgtgaaatgc tctcggctat     2880

gtagcagctt ttgattccct gcatacccta ggctgctgcc cctatcctgt cccttgttta     2940

taacattgag aggttttcta gggcacatac tgagtgagag cagtgttgag aagtcgggga     3000

aaatggtgac tacttttaga gcaaggctgg gcatcagcac ctgtccagct ctacttgtgt     3060

gatgtttcag gaactcagcc cctttttctg cctaggataa ggagctgaaa gattaacttg     3120

gatcttctaa tggtccaaat cttttggtca caataaagag tctccaaatt agagactgca     3180

tgttagttct ggatggattt ggtggcctga catgataccc tgccagctgt gaggggaccc     3240

cgtttttaag atgcatggcc aagctctctg caaatggaaa tgcttacact gggtgttggg     3300

gatgtttgct acctcctgct atttttgtgg ttttggttct cccactatgg taggacccct     3360

ggccagcatt gtggcttgtc atgtcagccc cattgactac cttctcatgc tctgaggtac     3420

tactgcctct gcagcacaaa tttctatttc tgtcaataaa aggagatgaa aatattctaa     3480

aaaa                                                                  3484


<210>  2298
<211>  3282
<212>  DNA
<213>  homo sapiens

<400>  2298
cgctccccgc tgcctattct catccggggt cacgtcggtc ttccgggtgt ctttgacagg       60

gttttctacg ccgctttttc ggcgactttt tgctcttccg ctttttgcca ccgcccccaa      120

ccttctatat ccttgcagcc cctacctttt cttgtgttgc tcctcccctg gcagccgtga      180

ggggggttag atctcagccg gagccggagc tgggcctagc tgtcccacgg gccaccacta      240

cctcctttgg ttcgggagaa agctacgacc aagtacgccc agctcgggcc ttagaacttc      300

tgaacgggca gtgcgggtag gccctgctta gcccttcccg gaggacacct gaccaaaaga      360

ggaagatagt cttgggaccc ttgcatggtg tttcaaaggg tggtgaagaa ctaaggtaga      420

agaatacatg ttcacttcca gtgaacaaga gcatgttccc aaactcaatt ttgggtcgcc      480

cacccttcac tccaaatcat caacaacata ataacttctt taccctgtca cctactgttt      540

attcacacca gcagcttata gatgcacaat tcaactttca gaatgcagac ttgtctagag      600

ctgtgtcatt acagcagctg acatatggaa atgtcagtcc aatacagacc tcagcttccc      660

cattatttcg aggaaggaag agattaagcg atgaaaaaaa ccttcctctt gacggtaaac      720

ggcaacgttt ccattcaccc caccaagagc caactgtagt taaccagata gtgcctttat      780

caggtgaacg aagatactca atgccaccat tgtttcatac acattatgta ccagatatag      840

tcagatgtgt tccacctttt cgagaaattg catttttaga acctagagaa atcacactgc      900

ctgaggccaa agataagttg agtcagcaga tactggagtt atttgaaaca tgtcagcagc      960

aaataagtga tttaaagaag aaagaactct gtcgaacaca gctgcagaga gaaattcagc     1020

tgttatttcc acaaagcaga ctttttttgg ttgggtcctc tttaaatgga tttggtaccc     1080

ggagcagtga tggtgattta tgcctagttg ttaaggaaga accatgtttt tttcaggtaa     1140

atcagaagac tgaagcacgg catatactca ccttagtcca taaacacttc tgtactagac     1200

tttcgggcta cattgagaga cctcagctga ttcgagcaaa agtgccaatt gtgaagttca     1260

gggataaagt cagttgtgtg gagtttgact tgaatgtaaa caatattgtt ggaataagaa     1320

acacattcct tctcagaact tatgcatacc ttgaaaatcg agttcgtccg ttagtgctgg     1380

tgattaagaa gtgggcaagt caccatcaga taaatgatgc cagtcgtggt actttaagca     1440

gctatagtct tgtattgatg gttttgcact atttacaaac cctacctgaa cccatccttc     1500

catccctcca aaaaatttac ccagagtctt ttagtcctgc tatacagctg caccttgtac     1560

atcaagctcc atgtaatgtt cctccttacc tctcaaagaa tgaatcaaac cttggggacc     1620

tcttactggg ctttcttaaa tattatgcta cagaatttga ctggaatagt caaatgattt     1680

cagttcgtga agccaaagcc attccaaggc ctgatggtat tgaatggaga aataaataca     1740

tctgtgtaga agaacctttt gatggaacaa atacagccag agcagtgcac gaaaagcaga     1800

aatttgatat gatcaaggat caatttttaa agtcatggca cagattgaaa aacaagagag     1860

atttgaacag tatactacct gtaagagctg ctgtcctgaa aagataactg gcctctattt     1920

cttaataaat tcttccaaga aataaagaac aatagtttca tcataataca ttatgtttac     1980

ctccatcata gttgcttttt tcatagttct tgttttcatg ttttattttt aaaaagacat     2040

ataaagattg catattttat tatgacattt cctaataaac ccctttgatt taaaaatgta     2100

tttttaaaaa tgtttacatt gatgatgagt aatattgcat gtgttttcag gtgatcagat     2160

aaaatatatt ttgggaaatt aactgaacaa ataaaaagtt tttgatataa cttcaattaa     2220

ttgtaccaca tgctaatcct gaagagatgt gtagaatttt ggaaagggtc taattcatac     2280

atgcttaaag tataacctac gttagatagt ttgttgtcaa agtctgttct agtaaagtga     2340

agattcaagt cagttgttca gttacttgaa gcaaaacgaa atctttcatt tcagtcaaat     2400

cactgcagtc atgaaatact gaacaattgc cttaagtctt tgcttgactc actgggatag     2460

actgaggctt tgggtgtgtc tgtattagca tttcattagt acttcacatg cttttgatgt     2520

actcttgaga ttgctttaaa ttttgtattg aaacaacaat acattttgca ctgtagtaat     2580

gggagcacta actcttacaa cagttagtga atcgttttaa agaatcagtt cagtgtagac     2640

attttgaaaa gattgtttcc tgtgctttac gatagcttag tgcaatgtgc acttctgttt     2700

tacttgccat tttcctgctc tgttttctct gtgacatgaa gcaacagaaa ctgagatcaa     2760

agttaagatt atatcctgtt tgtagtatca gatatttttc tgtgtacaat tataggattg     2820

taatctaaac tggaattttt aggcagtaag tcaccacaaa atgttttaga taagacacaa     2880

taaaattatt ataaataaaa gcttaatgtt tgtaaaaaat ctctttttta gtatttcttt     2940

tttcacatga aagaagtggt ggctgctaaa aaaaaagcta cagtgtttat taagggtctt     3000

tttgatttat gtaaatattt gtaaattggt cagtgcctgt aaatttaaat ataaaaagta     3060

accttgaaaa cagttttaac tttttcaaaa gaactatgtc caacattttt tagacctgct     3120

gtagtacagt tttgtacctc taacgtattt tttttttgca gaccaaatgc taaaactttt     3180

gcttttcttt gacttgtaaa aggtgcacat tttcattttc ttccttaagt tcaaattttt     3240

gtatgatgtc aaatgcaata aaatttatat atggacattg tt                        3282


<210>  2299
<211>  3248
<212>  DNA
<213>  homo sapiens

<400>  2299
cgctccccgc tgcctattct catccggggt cacgtcggtc ttccgggtgt ctttgacagg       60

gttttctacg ccgctttttc ggcgactttt tgctcttccg ctttttgcca ccgcccccaa      120

ccttctatat ccttgcagcc cctacctttt cttgtgttgc tcctcccctg gcagccgtga      180

ggggggttag atctcagccg gagccggagc tgggcctagc tgtcccacgg gccaccacta      240

cctcctttgg ttcgggagaa agctacgacc aagtacgccc agctcgggcc ttagaacttc      300

tgaacgggca gtgcgggacc aaaagaggaa gatagtcttg ggacccttgc atggtgtttc      360

aaagggtggt gaagaactaa ggtagaagaa tacatgttca cttccagtga acaagagcat      420

gttcccaaac tcaattttgg gtcgcccacc cttcactcca aatcatcaac aacataataa      480

cttctttacc ctgtcaccta ctgtttattc acaccagcag cttatagatg cacaattcaa      540

ctttcagaat gcagacttgt ctagagctgt gtcattacag cagctgacat atggaaatgt      600

cagtccaata cagacctcag cttccccatt atttcgagga aggaagagat taagcgatga      660

aaaaaacctt cctcttgacg gtaaacggca acgtttccat tcaccccacc aagagccaac      720

tgtagttaac cagatagtgc ctttatcagg tgaacgaaga tactcaatgc caccattgtt      780

tcatacacat tatgtaccag atatagtcag atgtgttcca ccttttcgag aaattgcatt      840

tttagaacct agagaaatca cactgcctga ggccaaagat aagttgagtc agcagatact      900

ggagttattt gaaacatgtc agcagcaaat aagtgattta aagaagaaag aactctgtcg      960

aacacagctg cagagagaaa ttcagctgtt atttccacaa agcagacttt ttttggttgg     1020

gtcctcttta aatggatttg gtacccggag cagtgatggt gatttatgcc tagttgttaa     1080

ggaagaacca tgtttttttc aggtaaatca gaagactgaa gcacggcata tactcacctt     1140

agtccataaa cacttctgta ctagactttc gggctacatt gagagacctc agctgattcg     1200

agcaaaagtg ccaattgtga agttcaggga taaagtcagt tgtgtggagt ttgacttgaa     1260

tgtaaacaat attgttggaa taagaaacac attccttctc agaacttatg cataccttga     1320

aaatcgagtt cgtccgttag tgctggtgat taagaagtgg gcaagtcacc atcagataaa     1380

tgatgccagt cgtggtactt taagcagcta tagtcttgta ttgatggttt tgcactattt     1440

acaaacccta cctgaaccca tccttccatc cctccaaaaa atttacccag agtcttttag     1500

tcctgctata cagctgcacc ttgtacatca agctccatgt aatgttcctc cttacctctc     1560

aaagaatgaa tcaaaccttg gggacctctt actgggcttt cttaaatatt atgctacaga     1620

atttgactgg aatagtcaaa tgatttcagt tcgtgaagcc aaagccattc caaggcctga     1680

tggtattgaa tggagaaata aatacatctg tgtagaagaa ccttttgatg gaacaaatac     1740

agccagagca gtgcacgaaa agcagaaatt tgatatgatc aaggatcaat ttttaaagtc     1800

atggcacaga ttgaaaaaca agagagattt gaacagtata ctacctgtaa gagctgctgt     1860

cctgaaaaga taactggcct ctatttctta ataaattctt ccaagaaata aagaacaata     1920

gtttcatcat aatacattat gtttacctcc atcatagttg cttttttcat agttcttgtt     1980

ttcatgtttt atttttaaaa agacatataa agattgcata ttttattatg acatttccta     2040

ataaacccct ttgatttaaa aatgtatttt taaaaatgtt tacattgatg atgagtaata     2100

ttgcatgtgt tttcaggtga tcagataaaa tatattttgg gaaattaact gaacaaataa     2160

aaagtttttg atataacttc aattaattgt accacatgct aatcctgaag agatgtgtag     2220

aattttggaa agggtctaat tcatacatgc ttaaagtata acctacgtta gatagtttgt     2280

tgtcaaagtc tgttctagta aagtgaagat tcaagtcagt tgttcagtta cttgaagcaa     2340

aacgaaatct ttcatttcag tcaaatcact gcagtcatga aatactgaac aattgcctta     2400

agtctttgct tgactcactg ggatagactg aggctttggg tgtgtctgta ttagcatttc     2460

attagtactt cacatgcttt tgatgtactc ttgagattgc tttaaatttt gtattgaaac     2520

aacaatacat tttgcactgt agtaatggga gcactaactc ttacaacagt tagtgaatcg     2580

ttttaaagaa tcagttcagt gtagacattt tgaaaagatt gtttcctgtg ctttacgata     2640

gcttagtgca atgtgcactt ctgttttact tgccattttc ctgctctgtt ttctctgtga     2700

catgaagcaa cagaaactga gatcaaagtt aagattatat cctgtttgta gtatcagata     2760

tttttctgtg tacaattata ggattgtaat ctaaactgga atttttaggc agtaagtcac     2820

cacaaaatgt tttagataag acacaataaa attattataa ataaaagctt aatgtttgta     2880

aaaaatctct tttttagtat ttcttttttc acatgaaaga agtggtggct gctaaaaaaa     2940

aagctacagt gtttattaag ggtctttttg atttatgtaa atatttgtaa attggtcagt     3000

gcctgtaaat ttaaatataa aaagtaacct tgaaaacagt tttaactttt tcaaaagaac     3060

tatgtccaac attttttaga cctgctgtag tacagttttg tacctctaac gtattttttt     3120

tttgcagacc aaatgctaaa acttttgctt ttctttgact tgtaaaaggt gcacattttc     3180

attttcttcc ttaagttcaa atttttgtat gatgtcaaat gcaataaaat ttatatatgg     3240

acattgtt                                                              3248


<210>  2300
<211>  3523
<212>  DNA
<213>  homo sapiens

<400>  2300
cgctccccgc tgcctattct catccggggt cacgtcggtc ttccgggtgt ctttgacagg       60

gttttctacg ccgctttttc ggcgactttt tgctcttccg ctttttgcca ccgcccccaa      120

ccttctatat ccttgcagcc cctacctttt cttgtgttgc tcctcccctg gcagccgtga      180

ggggggttag atctcagccg gagccggagc tgggcctagc tgtcccacgg gccaccacta      240

cctcctttgg ttcgggagaa agctacgacc aagtacgccc agctcgggcc ttagaacttc      300

tgaacgggca gtgcgggtag gccctgctta gcccttcccg gaggacacct gtgagtttag      360

ggggtttcgg agaggaacgc agcagtgtag gcccaggtcg gcggcggggc acgggaaact      420

tttccgaaac ggtagcgttt tgttttgcgt gggaggttcc agcagtatct cttggttatt      480

ccaaatttat gggcggcatc tgggctgctg tacattttga agaatcttag gaccgcttac      540

tttgcttact cgttttctat tcctcgcgta ctgcctcgtc caccactcca ggaccaaaag      600

aggaagatag tcttgggacc cttgcatggt gtttcaaagg gtggtgaaga actaaggtag      660

aagaatacat gttcacttcc agtgaacaag agcatgttcc caaactcaat tttgggtcgc      720

ccacccttca ctccaaatca tcaacaacat aataacttct ttaccctgtc acctactgtt      780

tattcacacc agcagcttat agatgcacaa ttcaactttc agaatgcaga cttgtctaga      840

gctgtgtcat tacagcagct gacatatgga aatgtcagtc caatacagac ctcagcttcc      900

ccattatttc gaggaaggaa gagattaagc gatgaaaaaa accttcctct tgacggtaaa      960

cggcaacgtt tccattcacc ccaccaagag ccaactgtag ttaaccagat agtgccttta     1020

tcaggtgaac gaagatactc aatgccacca ttgtttcata cacattatgt accagatata     1080

gtcagatgtg ttccaccttt tcgagaaatt gcatttttag aacctagaga aatcacactg     1140

cctgaggcca aagataagtt gagtcagcag atactggagt tatttgaaac atgtcagcag     1200

caaataagtg atttaaagaa gaaagaactc tgtcgaacac agctgcagag agaaattcag     1260

ctgttatttc cacaaagcag actttttttg gttgggtcct ctttaaatgg atttggtacc     1320

cggagcagtg atggtgattt atgcctagtt gttaaggaag aaccatgttt ttttcaggta     1380

aatcagaaga ctgaagcacg gcatatactc accttagtcc ataaacactt ctgtactaga     1440

ctttcgggct acattgagag acctcagctg attcgagcaa aagtgccaat tgtgaagttc     1500

agggataaag tcagttgtgt ggagtttgac ttgaatgtaa acaatattgt tggaataaga     1560

aacacattcc ttctcagaac ttatgcatac cttgaaaatc gagttcgtcc gttagtgctg     1620

gtgattaaga agtgggcaag tcaccatcag ataaatgatg ccagtcgtgg tactttaagc     1680

agctatagtc ttgtattgat ggttttgcac tatttacaaa ccctacctga acccatcctt     1740

ccatccctcc aaaaaattta cccagagtct tttagtcctg ctatacagct gcaccttgta     1800

catcaagctc catgtaatgt tcctccttac ctctcaaaga atgaatcaaa ccttggggac     1860

ctcttactgg gctttcttaa atattatgct acagaatttg actggaatag tcaaatgatt     1920

tcagttcgtg aagccaaagc cattccaagg cctgatggta ttgaatggag aaataaatac     1980

atctgtgtag aagaaccttt tgatggaaca aatacagcca gagcagtgca cgaaaagcag     2040

aaatttgata tgatcaagga tcaattttta aagtcatggc acagattgaa aaacaagaga     2100

gatttgaaca gtatactacc tgtaagagct gctgtcctga aaagataact ggcctctatt     2160

tcttaataaa ttcttccaag aaataaagaa caatagtttc atcataatac attatgttta     2220

cctccatcat agttgctttt ttcatagttc ttgttttcat gttttatttt taaaaagaca     2280

tataaagatt gcatatttta ttatgacatt tcctaataaa cccctttgat ttaaaaatgt     2340

atttttaaaa atgtttacat tgatgatgag taatattgca tgtgttttca ggtgatcaga     2400

taaaatatat tttgggaaat taactgaaca aataaaaagt ttttgatata acttcaatta     2460

attgtaccac atgctaatcc tgaagagatg tgtagaattt tggaaagggt ctaattcata     2520

catgcttaaa gtataaccta cgttagatag tttgttgtca aagtctgttc tagtaaagtg     2580

aagattcaag tcagttgttc agttacttga agcaaaacga aatctttcat ttcagtcaaa     2640

tcactgcagt catgaaatac tgaacaattg ccttaagtct ttgcttgact cactgggata     2700

gactgaggct ttgggtgtgt ctgtattagc atttcattag tacttcacat gcttttgatg     2760

tactcttgag attgctttaa attttgtatt gaaacaacaa tacattttgc actgtagtaa     2820

tgggagcact aactcttaca acagttagtg aatcgtttta aagaatcagt tcagtgtaga     2880

cattttgaaa agattgtttc ctgtgcttta cgatagctta gtgcaatgtg cacttctgtt     2940

ttacttgcca ttttcctgct ctgttttctc tgtgacatga agcaacagaa actgagatca     3000

aagttaagat tatatcctgt ttgtagtatc agatattttt ctgtgtacaa ttataggatt     3060

gtaatctaaa ctggaatttt taggcagtaa gtcaccacaa aatgttttag ataagacaca     3120

ataaaattat tataaataaa agcttaatgt ttgtaaaaaa tctctttttt agtatttctt     3180

ttttcacatg aaagaagtgg tggctgctaa aaaaaaagct acagtgttta ttaagggtct     3240

ttttgattta tgtaaatatt tgtaaattgg tcagtgcctg taaatttaaa tataaaaagt     3300

aaccttgaaa acagttttaa ctttttcaaa agaactatgt ccaacatttt ttagacctgc     3360

tgtagtacag ttttgtacct ctaacgtatt ttttttttgc agaccaaatg ctaaaacttt     3420

tgcttttctt tgacttgtaa aaggtgcaca ttttcatttt cttccttaag ttcaaatttt     3480

tgtatgatgt caaatgcaat aaaatttata tatggacatt gtt                       3523


<210>  2301
<211>  9351
<212>  DNA
<213>  homo sapiens

<400>  2301
aaccgtcccc aacggtcgcc agcgcgcggc tcccgggccc cctcgctcct cccctctggc       60

ccctccgagc gctgggggtg cttccctccc cgcctcctcg cactcccact cgcgggcacg      120

ccggtggctg tgccgccatg ccccaccaca ggctgctcac gggcctaggc gcggcggccc      180

gagatagggg cccctgagcc tcccggggga ggagagaggc agcgagccgc gctccgcccc      240

ctccccccgg gccgccgccg ccgccgcctc gccgccccag cctggcggga gaaggaggag      300

gagcagcagg cctccgggcc cggcgccgcc gcccgcagga catttctgat ttatttgcat      360

ccttgaagag catctgtaga agaggaagta aaagatgggt gtgaaaacat ttactcatag      420

ctcctcttcc cacagccagg aaatgcttgg aaagctaaat atgctgcgaa atgatggaca      480

tttttgtgat atcactattc gtgtccagga caaaatcttc cgggcacata aggtggtact      540

agcagcttgc agtgatttct ttcgcaccaa acttgtaggc caagccgagg atgagaacaa      600

gaatgtgttg gatctgcatc atgttacagt gactggcttt atacctcttt tagaatatgc      660

ttacacagcc actctatcaa ttaacacaga aaatattatt gatgttctag cagcagccag      720

ctatatgcaa atgttcagtg ttgccagcac ctgctcagag ttcatgaaat caagcatttt      780

atggaataca cccaacagcc aacctgaaaa gggtctagat gctggacaag aaaataattc      840

taactgcaat tttacttctc gagatgggag catttctccc gtgtcctcag agtgcagtgt      900

ggtagaaaga accattcctg tctgccgaga atcccggaga aagcgcaaaa gctacattgt      960

tatgtctcct gaaagtcctg taaagtgtgg cacacaaaca agctcacccc aggtattgaa     1020

ttcttcagct tcctactcag aaaatagaaa ccaaccagtt gactcttcct tagcttttcc     1080

ttggactttt ccttttggaa ttgatcgaag gattcagcct gagaaagtta agcaagcaga     1140

aaatacccgg actttagaat tacctggccc atctgagacc ggtagaagaa tggctgatta     1200

tgtgacttgt gagagcacaa aaactacctt gcctttaggt accgaagaag atgtccgggt     1260

caaagtagaa agattaagtg atgaggaggt ccatgaggaa gtgtcccagc ctgtcagtgc     1320

atctcagagt tcgctgagtg atcagcagac agttccagga agtgaacaag tccaagagga     1380

ccttctgatt agtccacagt cttcctctat aggctcagta gatgaaggcg tttctgaggg     1440

cttgcctaca cttcaaagca cgtctagcac taatgctcct ccggatgatg atgatcgatt     1500

ggaaaatgtt cagtatccct accaactcta cattgctcct tccaccagca gtacagagcg     1560

accaagtcca aatggtcccg acagaccttt tcagtgtcca acctgcgggg tgcgattcac     1620

ccgtattcag aacctaaagc agcacatgct catccactca ggaattaaac catttcagtg     1680

tgaccgctgt gggaaaaagt tcaccagggc ttactcgcta aagatgcatc gcctaaagca     1740

tgaagtgatt tcctagtacc ggactactta aaccaggaac aagaagagac ccttgttcaa     1800

tatgatcttg gagaacacgg ttttgaaagc aactcctctg ttcaaatgcc tgtcatttca     1860

caggtctcct caacccagaa ttgtgaaagc acttttccct tggggtctct tggtgggctg     1920

gcagaaaaag aggaagaagt gccagagcag ccaaagagca gtgcttgtgc tgaggcaacc     1980

agagatgacc ccccaaaatc agagctgtct tctataacta ttgagtagtt ttgtgatttg     2040

gcttcagttt tgttttttgg aaagtgcctg tgcttggtct tgtacattta aatttaattt     2100

aattttttaa acaaaaaaag ccgggtggga gggaggggga gattgggaaa gaatttccct     2160

ttttactttc tgagccctga aactgatttt atttttccta actgagagat tgcttctgta     2220

agtacacaat aacatgatgt tgaaacagaa actatgagac ttaaggagaa ctggttgact     2280

taaaacatat accagttcct tcttccattg ttaaaagtag gctaacaaca gatcattagc     2340

tagagaggaa atcagatgat tattgacctt cttgagacaa gagggtacat gagaaactaa     2400

ttactaaaca gcttgacaaa tggcctgagt agatacttac tgctgtacac aggatgttgt     2460

ataatatttt gtaaagcctg ttgtttttgg aagtatttat ggtaagcttt cttaaaaatt     2520

attatggtaa atacttctga aatccggcgt acttttcttt aagctttgtc atttctgtta     2580

tgatttttca tggtgaaatt ttggtactga gatgggcatt ctctgtacct ttatagtacc     2640

actccaaagg caaggaacca tgattgacaa cagtcaagct gtggatgaaa tgaccaggaa     2700

cggagaatga agtatgtaaa tcccagcttc ataggaactc ttctcatact gcttttcaga     2760

ttaaaattgc tgtttacctg gtctccgaat gtaatgcctg actgtgtcat tgcccggatc     2820

agttttcccc ctgccccatc aatatgttct cttgcatata ttggcgtgct gccatataaa     2880

gtaaaaatac tggagatatt ctatatttta tatataggtt tatgtgttgt tggggatgtt     2940

ttcattgtgc tcttttggac ataataaata attctctatt gaggctacat tctttttttt     3000

tttctttttt tttaaaagaa tggcatctca ctctgttgcc caggctggag tatagtggct     3060

aagtcatagc tcactgcagc ttcgaactcc tgggctcagg ccattctcct gcctcagcct     3120

cttgagtatc taggattata ggcatgctcc accacacctg gttaacttca tttttatttt     3180

ttgtagagat gaggtctcac tatggtgccc aggctggtct tgaactccta gaccaagtga     3240

tcctcctcct ttggcctccc agactgctgg gatcactgca ccggccaagg ctgcattctt     3300

aacccaacta gattgtttac tgaatcccat atgacagcga tacattgtcc ttacatattt     3360

atttttagac attgcaaagt tattaaaaac agttaactat agtttttaca caacgtaggc     3420

aacaatgaag agtatagact gtaagatttt catctatgac tcataaatct gggagaaaaa     3480

aattattaag actaatgaga aactgaaaac cttaaactaa tgaatattat ttctgctgct     3540

aaaaatatga aactttctgg tctgtagttg aaatttgtat gatcctctag acttgggtat     3600

acttttcatc tggtgccatt aaagcatctc taatattgat cctaaatatt tgtaagtcca     3660

tgagcagtga actttggaat aagtttctgt gtagataccc aaagtttaat aattatgaga     3720

gcacctgatt tgatagacag aaaatacagt tctttagtca aaacacaaga tctgaatttt     3780

gttcaggtgc tagaccatac taaatgtata tatttttaat tatagtgatt tgtttcattt     3840

ttttagattg gctaattctg taattttttc cccaaaaaca tgtgaagaaa ggaaaagtaa     3900

attaaattcc ttagaactgt tttaggttaa gattctctgt gtctgcccat attctgcagt     3960

ccttaacttg ttttcaactc tttacctcac tcatgaactt gtttttaccc atttgctgcc     4020

aaacataggt gtgttccctt caggagaatc agcatataca ggttatgata ggctcccacc     4080

atttatgctt cttcactgat agggttgcat tactttctgc agcagactat aatacttcat     4140

atagtactgc tgtgtctcaa ctggaaaggt caggaatttt aatgttacgt tgtggtcttt     4200

gaaaactgtt aggcctagca atagataaat ctcaaaatta attttaaaat ctgtattgac     4260

aagaataggt aaaattatga ccaggaatca ttgttaccct tagttccaag aggtggtttt     4320

tgaaagagca agaggaaaga aaaaagaaaa gaaggaaaga agaataaaga agagaaacgt     4380

gtaagaatgg tttgcagatt gattggttaa aagtgttttt agcacatccc caaccctgaa     4440

aacttcgcat taagagccaa gcacaatgtt ggtagctcca agatattctg actgtgttct     4500

cagaatgagg gattacccat cactgggtat tccttcccaa gtagaaactt tagattttca     4560

ctggtaatac acattgccaa gttttatggg aaatctgaat atactgtgaa aatgcatatc     4620

tggttagttg tctgctgccc agatcttatc aataccagta actaaccagt atttaacata     4680

aaatgataca aataaaggcc tttttctatt tcagtgaggg tacatttttc ttgatatata     4740

tgtactttaa ggatattgga tctgtttatg gatctgtttt aggaaacaga tttgcaaggg     4800

ataattgtat atatagtagt atttaggttt atttcaaatt catcttaggg atgcctagat     4860

gcataatttt taccaggaca tattgaaaat attgcaaaga gatagccagt tatattatcc     4920

cattcattag aaattaccag tgtaactaaa cataaatatt ccagtttaga gtgcttaaac     4980

gtagctatct ttcttaaggc caggagggta actttgtggt atctaaaggg cttaaatttc     5040

agaatgcaga ataaattgcc tttttaaaac caagcatttt gtacaagctt ttattttcag     5100

ttttttaact accaaatagg tgtgatgtac tttagaagta aacaaagatg ttcacccatg     5160

ataatggatg ttaaagctcc tgcagttgtt cttttcgtgt ttaaagggta tattctaata     5220

gtggaagcat caaacatgtc agtgatttca tctcattcag aaataaagag attaatattg     5280

gtctttattt tttggcattt taagttttat ataaatggat gcagatggag attatcaccc     5340

acaaatatat ttaaatggat ttttcttaat ttgaatttca agtaatcttt ttatttcaag     5400

taattagtta cgcatttagt tacattgcca gttttttttt tttatcaatt tcagtaagac     5460

aaaatatact aaaatgttta aatagcctca ttcaatctta cattttgaca tttcagcaat     5520

cattctggct tacagtaatt agatcccctg ttacgacaca tgccctttgt tcttaataac     5580

tagcaaaaaa aaaaaaaaaa aaaaactttc atcttgttaa aatactttgc caaatgaaat     5640

agactagtca atacatctga tgtccataat tattggtaac tcagttacct tctaactaat     5700

aggctggttc aggagactct cccagtttat aaatggttct cttgggagcc tttggaagct     5760

gtattaaatc tttcagtctt ttatttctaa ttttttctct taatctaaat agaggccagt     5820

tatctatttt atcagctttt attcttgaag attctcagat tatgttttag tcccttttag     5880

ctttaatagt ccttgaaaaa tacattactg tataatgtgg caattctgta acagagactt     5940

attacttgaa tgaataatcc taaaatttta atattttagc tgaagtttga gatttgtgga     6000

atgaacaaaa gaattagaaa ctttcatatg ttactttgtt tcagtcatct gcaaagtatg     6060

aagctgtaat tctgaaatac acatccaagt gaatgagaat taaaaatttt ctaaatatta     6120

atactaactg ggaaaaaaaa actagtgtga agtttacagt tagaagaaac agacccaaag     6180

ttgccagaag gtaataaata aatgtagttt tcactgtaag taagttattg acgtaagatg     6240

ctttatttgt aatatattta gattttgaaa gttattgaga gatgaatgta taaaagctaa     6300

attttctttt ctgaagcagt gaaacaaaat tggggtaaca aggaagctct gttgtggcaa     6360

acatgtctat gaggaatatt aaaactaagc atactcccac aggctttaaa ctcaaactat     6420

gaacatttaa attaagttgt tccttatttt gcctataccc atttttatct ttcattgtcg     6480

tttttgcttg acagtatggt gacagagtat ttttatttgg aaagtcctca gcaagatgaa     6540

ttagccaaaa gcaataatgg ttcagattaa acaataaagt ggaattgatt caatcccagg     6600

ctcaactaag aacagtcgct ctctggatgt ttcattttag acgatagata agttgagatg     6660

ttgtaatatt tatggggggt taagcctgtg tcagttatgg gatgaagact tgtagtacca     6720

gtaccatcag tggtcatact tttttttaac tttttactaa actaatacag ttagacattt     6780

ccactctatc gtgattatat ttttatgatg ggaaaataaa aacacttcca tgtttttata     6840

aatagtctct gcaaagattt cagatgttat tggtatctcg gtttggcagt atctgaaaaa     6900

ttgagattgt ctttgaaatg tttgtgctac ttttacttaa gtaaaccccc actgtgcaag     6960

acccaggccg gcttcagcta ataccaaggt ttctgtgtgc ataatagttt acagagaact     7020

taagagtaag gactgcggat taaaaacaaa acttttttta actttaaaat ttttagtttt     7080

tgttcaaagt acctggttta taaagtcaaa ttcttttatt agttcctttc tcgtttaaat     7140

tgactgatgt tgctgatgaa gcttaaagtc ccaggcacgg ttgtggcgat atactgataa     7200

aattggtgcc tagtggtggg aggagctcca gtgtcaggac ttttattaaa aggcccttgt     7260

tttcccaaat gccaatctag ccacatttag atttcattat tcaataaaac agatgaaaaa     7320

tcatcccata aatgaatgtt gaggttacca aagtacatca cctgctgagg aaggataaat     7380

cttcctgctt taagggagcc ctgtcatctc tcctcttaat gcacgtttcc cttggtatta     7440

gtggaagctg tgttcaagat gggaagcctt tcctgcagtt cttagaaaca cctgctttct     7500

aaggagagcc ttttctagga ttagcttatg tgtgttttct ctaggcgatt ttttatttca     7560

gttaccaatt taattttcaa gttgacagat gctgtgtaaa gtctctcata atgagagtag     7620

tccattaaat tgttgaaagt tgcactgctt ttcatctttc aggtacctga aatgagtgac     7680

atcaggtatt tggaaggagt aagatcataa actgtattca ttttcttcct tgtacaaagt     7740

gatgacttct aatgcttata tctcaaggta ttttttaaaa aagcaacggt ccctaataga     7800

gtaaaatttg gttttggtcc aagttcccaa taatgtattt aatgtttctg ttgtttactg     7860

gtgcctcccg ttgcatcagg tagagattgc ctgcctcttt gtagggcagc cttgtggcac     7920

cttatgtcca acttggagga tagtatatgg cttctttgtg cctctactat cttttcaaaa     7980

gccattttat aaaaatccta ggtagcctat tttaatattt aaatatatat atttgtgaaa     8040

gaacttttag aacagacctt ttctttttac tttaaaattc ctgtatttcc atttttaaga     8100

gtaaatttaa tctccaggat ttagaagtgt ctttccagag aagcataatg agaaagtcag     8160

actgaggtaa taagaccaga attaagtgat agaagaaact gttgtttggt taaaggacac     8220

agatttgaag gaaaaaaatt ttgatgtaac aattttttaa ataaaatttt gtttttctgt     8280

aatgtcatat ttgctgctac agtagctcaa tattttacag ggctaacata aagctggctc     8340

catttaaaaa ctggagtact tcctagtgca gccagcctag gcggaaactg tacaccatgg     8400

tcttccagat gggtgactga tggctttggg tagctgatgc atgctttaat atttgcctat     8460

agcccggcag caaggaagtc ggggcggggg gactttttta ccctgccagt tatagcattg     8520

tgattctttc tgggcactgg cattttgtga aactctcaag ggaaggtgat gcaggggaga     8580

aaatgtgaat taaattacat agatgggtgt ttttatgtct tctacccctt tcctagaatt     8640

agtacaactc ttaactgtgc cagtccccag ttcaccagct ttgtatccag tcgtcatctc     8700

attcaagtat ggctttactt ggtgacactg gccatagcta agttaacttg gcatgtttga     8760

cttttgacaa taacaaaaat ggttttggat tttgttttat ttccaaaaaa tgtatacaat     8820

atcagaactt cacattttat atactagtat ctggctatta gtattttaca ggaaccatag     8880

ttcttggtga ctacatatat atatatattt ttgtgacctt ttttgtaaac taagtgccgt     8940

ttcaacgtta caatcatttt tagggttatt gtaatcaatg tgaatatcat gttttttcaa     9000

atctgttctg agcctatagt gtttgctttg tgaacatgtg tattgtatat attctgtata     9060

gttatattgt actgaaatta gcttgtttga tataaggaaa atatgtattg agtacctttt     9120

tgctagcctg attgtttaat ctttttaaaa aaggtttaaa ctttttttaa aaaaaaaatc     9180

tttaaactgg cctttattac atggtcacac ataaagttgc agttaggaaa gggatgggca     9240

gggaaaaact agttttgagt gtctttagat agaaacatga gactaaggtt tgattttgtt     9300

ttcgttttct cattaaaata tcttatgctt tatggaataa aaaaaaaaaa a              9351


<210>  2302
<211>  5233
<212>  DNA
<213>  homo sapiens

<400>  2302
tgaccttctc tcctccctgt gtcttttttt ttcctttaga gatgggggtc ttgctctgtc       60

actccagcta gagcacagtg gtgcaatcgg agctcactga ctgcagcctg caactcctgg      120

gctcaagtga ttctgccgcc tcagcctctc aacgtgctgc gattagagag tctgtagaag      180

aggcgacacc agggcttcca aatgaacaac cgaaaggaag atatggaaat cacgtcccac      240

taccggcacc tgctgcggga gctcaacgag cagaggcagc acggcgtcct gtgcgacgtc      300

tgcgtggtcg tggagggcaa ggtcttcaag gcgcacaaga acgtcctgct gggcagcagc      360

cgctacttca agacgctcta ctgccaggtg cagaagacgt cggagcaggc cacggtcacg      420

cacctggaca tcgtcacggc ccagggcttc aaggccatca tcgacttcat gtactcagcg      480

cacctggcgc tcaccagcag gaacgtcatc gaggtgatgt cagccgccag cttcctgcag      540

atgacggaca tcgtgcaagc ctgccacgac ttcatcaagg cggcgctgga catcagcatc      600

aagtcggacg cctcagatga gcttgcggag ttcgagatcg gcgcctcgtc cagcagcagc      660

acggaagctc tcatctcggc cgtgatggct gggaggagca tctccccgtg gctggcacgg      720

cgaacgagtc ctgccaattc ttccggagac tcggccatcg ccagctgtca cgacggaggg      780

agcagctacg ggaaagagga tcaggagccc aaggccgatg gccctgatga tgtttcttca      840

cagcctctat ggcctggaga cgtgggctac gggcctctgc gcatcaagga agagcaggtt      900

tcaccgtctc agtacggagg gagcgagctg ccttctgcca aggacggtgc agtacagaac      960

tctttctcag agcagagtgc tggtgatgcc tggcagccca cgggccgaag gaagaatcgg     1020

aaaaacaaag agaccgtccg gcacatcaca cagcaggtgg aagatgacag ccgggccagc     1080

tccccggtgc cgtccttcct gccgacgtcg gggtggccgt tcagcagccg agactcaaat     1140

gcggacctgt ccgtcaccga agccagcagc tccgacagcc gaggagagag ggccgagctc     1200

tatgcacagg tggaggaggg tctcctggga ggagaagcca gctatctggg ccctcccctc     1260

accccagaga aggacgacgc cctgcatcag gccaccgcgg tggccaacct gcgcgcggcg     1320

ctcatgagta agaacagcct gctgtcgctg aaggccgacg tgctggggga tgacggctcc     1380

ctgctgttcg agtacctgcc cagaggggcc cactcgctgt ccctgaatga gttcacggtg     1440

atcaggaaga agttcaagtg tccgtactgc agcttctcgg ccatgcacca gtgcatcctc     1500

aagcgacaca tgcgctcgca cacgggagag cggccctacc cctgcgagat ctgcgggaag     1560

aagttcacgc ggcgcgagca catgaagcgc cacacgctgg tccacagcaa ggacaagaag     1620

tatgtgtgca aggtgtgcag ccgcgtcttc atgtccgccg ccagcgtggg catcaggcat     1680

ggctccaggc gccacggtgt gtgcaccgac tgtgctggcc gcggcatggc cgggcccctg     1740

gaccatggcg gcggaggcgg cgagggctct ccagaggcgc tgttcccagg cgacgggccc     1800

tatctggagg accctgagga cccacgaggg gaggcggagg agctgggcga ggacgacgag     1860

ggcctggccc ctgaggatgc gctgttggcg gacgacaagg atgaggaaga ctcgccgcgg     1920

ccgcgcagcc ccccaggagg ccctgacaag gacttcgcct ggctctccta ggcccgcccg     1980

ccggcagggt cggtggctgc ctcgctccgt ccacccgtgt gtgtgtccgg tgggtctcca     2040

ctgcggggcc agggccacgc tcacccctct cgcggcccct cctctgcttc cccctgaacc     2100

caccccccac ggaaaccagc cctgcgggct aagcaggtgc gaccccagca agaggggtgc     2160

tctgggacca gacatgaagt gagttggggg agggcacagg gtgggtttga gtgaagggag     2220

agcacggtcc taagtcccca gcaggtggtg cgggtgtgtg agtggcccct gtgatggcca     2280

gcctggcttg gacacgtgat gggcctgtgg ccgggtccag tgggcactgg gcggggtggt     2340

gtgttcggcc cagaggcccc tggcctgagc aggtgcagag ttttacagac acccggtcag     2400

cccggctgga gcccgccctc ccctccccta gcagccaggt cactgcctgt ggctgcagcc     2460

gtggcccgtg gtgcagccgt ggcccatggc agcctgtaga atccaggtgc acagagagcc     2520

ctgccaccgt cttacctctg ggctttggtg cttaacacac aacacagctg cagaccctgc     2580

tggaggccga gggctccagg tgctatctta ggtggacaca gccctggggg ctccttccag     2640

gaggggaccc tcagccctgt gccccccacc acttcaggcc acaccaggtt ccctctgcaa     2700

gggcctcggc tcagtcgtgt gcacttcctc ggagagcctt gggctgccac gtccaccccg     2760

ggctctgccc gtcctgttct gcccatggcc cagcccggcc gctcctgctg acccctcctg     2820

gacgggctgg agctgggctc ctgcctttgc tgctaacact ggaggcggtg ttcctaactg     2880

cagtgtgctg cttacacctc cccgcgtggg taaccaaatt tttaagtagt cagagacata     2940

tcgaggtagt tacataaaat tattttgttt ggcattattt ttctcactcg aagaaactat     3000

atagggttgt ttttccttta gcttgtgctc aagtcctctt gctgtgtttt cagaagcact     3060

cacatgttct ttcttttcct gagtgaaaag caaaggtccc acggtgtgtg ctgtggtgca     3120

ccgcctggct ttgggggtcc cggaggcagg ctgcctagac tcacagcctc gggaccgttg     3180

ccacggcctg tcttctcgtt caggcctgcc tctgacagca ctcaccatga ggacattcca     3240

tccttcaccc cctcctctgg cacaggccac cactgcggtg ctgtgccttc agatgggagg     3300

tgggcgcggt ggcctcctcc ttccctccag gacctgcccg tgtgaagacc ccccggagtg     3360

ctgagcttca gggctgcgtg gaaagagttt ttactctctt tttctagcct gtataccagg     3420

cttttcccca cattgtcagg tagagcacca gcttccctga ccgctgctgc tcggggaggg     3480

ctggggctgg ccgggggtcc tgtggaggag tacatggagg actccaggta cagcgcagga     3540

gtcacggctt ttgttttttg acattggccc ccggttctac caatgacagg gtgccctggc     3600

tggagctgtc atcacacaca cccctcagct cggaggctgt gggctcctca aagctggaga     3660

aagaggccaa gatttttctg cacacggagt gtggggatag gagccgggcc aagcgctggc     3720

ccctcagcgg tgagccctgc ccactcttac cgagcaaggt gggtggctct ggcacgagtc     3780

ccccaggggg agagcatggc taccagggag ctgcagcgga gccctccagc cctcacccca     3840

ggccagcccc accccggcct ctttgagaat tctcagaact ttgtaccttt cccctgattt     3900

ttaaaccctt tttctaaaca gactgacttt cttacaaaat gcatttggaa accagacctt     3960

tgctacccac caatgtctct gggttttgta ccagtccctg ctctcaggcc accctgccca     4020

ggacccaggc ccgcctcccc ctccacactc aggatgtcct gctccatctg gccggctcac     4080

tccgtgtggc ctgcctttgc tgaccgtttt ggggttcccc gccggagcta caggggcatt     4140

ttcttcccta aaaccaacag tgtcccactg acctccccaa gtgtttgctg cgtggcagat     4200

ttcctgttct tgttcgcagt ttgccgactg aagagtgtgg gatttccgag gcccaggtga     4260

gcacgtccat ctcaggaggc gtggagggaa aagacatgtc atgaagggtt ttttttatgt     4320

gactgatttt tttttaaatc gatgttcaaa ctaataaata tttttttatg aagaggaaaa     4380

atgtgtagat tacatttcac attttgtatt tttgtttgtg tctgtttgta ttttggtgtt     4440

tacaacacca aagtgggaaa tacagtccat tggggatggt gttatttggg ggcggggagg     4500

gggcagggac accacgattt ttctgtcaag ctctggatcc tgaccaggtt gtacactggg     4560

gctctctgag ctttgggaca caggacactg ccagggctac gtagggaact gactcagaag     4620

acgcagctta ctgcttccaa ctttgcacat cttcctcttt aaaaaactga gaaaatgcaa     4680

aaactggaac tttttgcaat attataaaag aagtaatctt attttagctc attctgtgac     4740

atgtgcgact cttaagaaag ccatacttaa tggtggtggt tttttttaga tcttatattg     4800

tgttttgtat gcagcccttt tagaactact tgtagtgagg gtgctgtgtg tgcttttctt     4860

aaatatttat ttttttcaac atgctttcaa cctgtcaaca aaaacaaaac acacaaaaaa     4920

agggcagtgt ttgaagattg ttgatttttt tctggggata atctatatta tattgacttc     4980

ctattactta ttataaacct gtgtttgtat tggagatgtg tctactattg ggggaagagg     5040

ttctcgtaat cgctcggtgg gaaatcatgg ctctgccgtc ctgcctctct gtggccgtgg     5100

gttcacgtgg cctctgcggt gagtctccaa gtttctgcct aggcgcctgt gcgtttcctt     5160

tctgtgacgg gattagctta gacatccttg caaagcgatc actttcaata aattgggaaa     5220

ttgctgctcc agc                                                        5233


<210>  2303
<211>  5233
<212>  DNA
<213>  homo sapiens

<400>  2303
tgaccttctc tcctccctgt gtcttttttt ttcctttaga gatgggggtc ttgctctgtc       60

actccagcta gagcacagtg gtgcaatcgg agctcactga ctgcagcctg caactcctgg      120

gctcaagtga ttctgccgcc tcagcctctc aacgtgctgc gattagagag tctgtagaag      180

aggcgacacc agggcttcca aatgaacaac cgaaaggaag atatggaaat cacgtcccac      240

taccggcacc tgctgcggga gctcaacgag cagaggcagc acggcgtcct gtgcgacgtc      300

tgcgtggtcg tggagggcaa ggtcttcaag gcgcacaaga acgtcctgct gggcagcagc      360

cgctacttca agacgctcta ctgccaggtg cagaagacgt cggagcaggc cacggtcacg      420

cacctggaca tcgtcacggc ccagggcttc aaggccatca tcgacttcat gtactcagcg      480

cacctggcgc tcaccagcag gaacgtcatc gaggtgatgt cagccgccag cttcctgcag      540

atgacggaca tcgtgcaagc ctgccacgac ttcatcaagg cggcgctgga catcagcatc      600

aagtcggacg cctcagatga gcttgcggag ttcgagatcg gcgcctcgtc cagcagcagc      660

acggaagctc tcatctcggc cgtgatggct gggaggagca tctccccgtg gctggcacgg      720

cgaacgagtc ctgccaattc ttccggagac tcggccatcg ccagctgtca cgacggaggg      780

agcagctacg ggaaagagga tcaggagccc aaggccgatg gccctgatga tgtttcttca      840

cagcctctat ggcctggaga cgtgggctac gggcctctgc gcatcaagga agagcaggtt      900

tcaccgtctc agtacggagg gagcgagctg ccttctgcca aggacggtgc agtacagaac      960

tctttctcag agcagagtgc tggtgatgcc tggcagccca cgggccgaag gaagaatcgg     1020

aaaaacaaag agaccgtccg gcacatcaca cagcaggtgg aagatgacag ccgggccagc     1080

tccccggtgc cgtccttcct gccgacgtcg gggtggccgt tcagcagccg agactcaaat     1140

gcggacctgt ccgtcaccga agccagcagc tccgacagcc gaggagagag ggccgagctc     1200

tatgcacagg tggaggaggg tctcctggga ggagaagcca gctatctggg ccctcccctc     1260

accccagaga aggacgacgc cctgcatcag gccaccgcgg tggccaacct gcgcgcggcg     1320

ctcatgagta agaacagcct gctgtcgctg aaggccgacg tgctggggga tgacggctcc     1380

ctgctgttcg agtacctgcc cagaggggcc cactcgctgt ccctgaatga gttcacggtg     1440

atcaggaaga agttcaagtg tccgtactgc agcttctcgg ccatgcacca gtgcatcctc     1500

aagcgacaca tgcgctcgca cacgggagag cggccctacc cctgcgagat ctgcgggaag     1560

aagttcacgc ggcgcgagca catgaagcgc cacacgctgg tccacagcaa ggacaagaag     1620

tatgtgtgca aggtgtgcag ccgcgtcttc atgtccgccg ccagcgtggg catcaggcat     1680

ggctccaggc gccacggtgt gtgcaccgac tgtgctggcc gcggcatggc cgggcccctg     1740

gaccatggcg gcggaggcgg cgagggctct ccagaggcgc tgttcccagg cgacgggccc     1800

tatctggagg accctgagga cccacgaggg gaggcggagg agctgggcga ggacgacgag     1860

ggcctggccc ctgaggatgc gctgttggcg gacgacaagg atgaggaaga ctcgccgcgg     1920

ccgcgcagcc ccccaggagg ccctgacaag gacttcgcct ggctctccta ggcccgcccg     1980

ccggcagggt cggtggctgc ctcgctccgt ccacccgtgt gtgtgtccgg tgggtctcca     2040

ctgcggggcc agggccacgc tcacccctct cgcggcccct cctctgcttc cccctgaacc     2100

caccccccac ggaaaccagc cctgcgggct aagcaggtgc gaccccagca agaggggtgc     2160

tctgggacca gacatgaagt gagttggggg agggcacagg gtgggtttga gtgaagggag     2220

agcacggtcc taagtcccca gcaggtggtg cgggtgtgtg agtggcccct gtgatggcca     2280

gcctggcttg gacacgtgat gggcctgtgg ccgggtccag tgggcactgg gcggggtggt     2340

gtgttcggcc cagaggcccc tggcctgagc aggtgcagag ttttacagac acccggtcag     2400

cccggctgga gcccgccctc ccctccccta gcagccaggt cactgcctgt ggctgcagcc     2460

gtggcccgtg gtgcagccgt ggcccatggc agcctgtaga atccaggtgc acagagagcc     2520

ctgccaccgt cttacctctg ggctttggtg cttaacacac aacacagctg cagaccctgc     2580

tggaggccga gggctccagg tgctatctta ggtggacaca gccctggggg ctccttccag     2640

gaggggaccc tcagccctgt gccccccacc acttcaggcc acaccaggtt ccctctgcaa     2700

gggcctcggc tcagtcgtgt gcacttcctc ggagagcctt gggctgccac gtccaccccg     2760

ggctctgccc gtcctgttct gcccatggcc cagcccggcc gctcctgctg acccctcctg     2820

gacgggctgg agctgggctc ctgcctttgc tgctaacact ggaggcggtg ttcctaactg     2880

cagtgtgctg cttacacctc cccgcgtggg taaccaaatt tttaagtagt cagagacata     2940

tcgaggtagt tacataaaat tattttgttt ggcattattt ttctcactcg aagaaactat     3000

atagggttgt ttttccttta gcttgtgctc aagtcctctt gctgtgtttt cagaagcact     3060

cacatgttct ttcttttcct gagtgaaaag caaaggtccc acggtgtgtg ctgtggtgca     3120

ccgcctggct ttgggggtcc cggaggcagg ctgcctagac tcacagcctc gggaccgttg     3180

ccacggcctg tcttctcgtt caggcctgcc tctgacagca ctcaccatga ggacattcca     3240

tccttcaccc cctcctctgg cacaggccac cactgcggtg ctgtgccttc agatgggagg     3300

tgggcgcggt ggcctcctcc ttccctccag gacctgcccg tgtgaagacc ccccggagtg     3360

ctgagcttca gggctgcgtg gaaagagttt ttactctctt tttctagcct gtataccagg     3420

cttttcccca cattgtcagg tagagcacca gcttccctga ccgctgctgc tcggggaggg     3480

ctggggctgg ccgggggtcc tgtggaggag tacatggagg actccaggta cagcgcagga     3540

gtcacggctt ttgttttttg acattggccc ccggttctac caatgacagg gtgccctggc     3600

tggagctgtc atcacacaca cccctcagct cggaggctgt gggctcctca aagctggaga     3660

aagaggccaa gatttttctg cacacggagt gtggggatag gagccgggcc aagcgctggc     3720

ccctcagcgg tgagccctgc ccactcttac cgagcaaggt gggtggctct ggcacgagtc     3780

ccccaggggg agagcatggc taccagggag ctgcagcgga gccctccagc cctcacccca     3840

ggccagcccc accccggcct ctttgagaat tctcagaact ttgtaccttt cccctgattt     3900

ttaaaccctt tttctaaaca gactgacttt cttacaaaat gcatttggaa accagacctt     3960

tgctacccac caatgtctct gggttttgta ccagtccctg ctctcaggcc accctgccca     4020

ggacccaggc ccgcctcccc ctccacactc aggatgtcct gctccatctg gccggctcac     4080

tccgtgtggc ctgcctttgc tgaccgtttt ggggttcccc gccggagcta caggggcatt     4140

ttcttcccta aaaccaacag tgtcccactg acctccccaa gtgtttgctg cgtggcagat     4200

ttcctgttct tgttcgcagt ttgccgactg aagagtgtgg gatttccgag gcccaggtga     4260

gcacgtccat ctcaggaggc gtggagggaa aagacatgtc atgaagggtt ttttttatgt     4320

gactgatttt tttttaaatc gatgttcaaa ctaataaata tttttttatg aagaggaaaa     4380

atgtgtagat tacatttcac attttgtatt tttgtttgtg tctgtttgta ttttggtgtt     4440

tacaacacca aagtgggaaa tacagtccat tggggatggt gttatttggg ggcggggagg     4500

gggcagggac accacgattt ttctgtcaag ctctggatcc tgaccaggtt gtacactggg     4560

gctctctgag ctttgggaca caggacactg ccagggctac gtagggaact gactcagaag     4620

acgcagctta ctgcttccaa ctttgcacat cttcctcttt aaaaaactga gaaaatgcaa     4680

aaactggaac tttttgcaat attataaaag aagtaatctt attttagctc attctgtgac     4740

atgtgcgact cttaagaaag ccatacttaa tggtggtggt tttttttaga tcttatattg     4800

tgttttgtat gcagcccttt tagaactact tgtagtgagg gtgctgtgtg tgcttttctt     4860

aaatatttat ttttttcaac atgctttcaa cctgtcaaca aaaacaaaac acacaaaaaa     4920

agggcagtgt ttgaagattg ttgatttttt tctggggata atctatatta tattgacttc     4980

ctattactta ttataaacct gtgtttgtat tggagatgtg tctactattg ggggaagagg     5040

ttctcgtaat cgctcggtgg gaaatcatgg ctctgccgtc ctgcctctct gtggccgtgg     5100

gttcacgtgg cctctgcggt gagtctccaa gtttctgcct aggcgcctgt gcgtttcctt     5160

tctgtgacgg gattagctta gacatccttg caaagcgatc actttcaata aattgggaaa     5220

ttgctgctcc agc                                                        5233


<210>  2304
<211>  6482
<212>  DNA
<213>  homo sapiens

<400>  2304
ggcggctgcg gcacctttaa gacaagggag gacccctctt gccctcggag aaaccaggaa       60

gggagtcgcg agcatcatac ggggctttgg ctgtactgta cagttactgt aggggcagtg      120

acgccgccgc cgccgcgcga gggagcgacc agggcagcgc gacgcgggca gagcgagcgc      180

cgcggacccc ggaggcgagc ggccgaggga gcccagtccc aacttcgggc cccggccccg      240

cgcgccccgg cccggccccg cgaggtctcg gcgcggaaga tggccggcgg cgtggacggc      300

cccatcggga tcccgttccc cgaccacagc agcgacatcc tgagtgggct gaacgagcag      360

cggacgcagg gcctgctgtg cgacgtggtg atcctggtgg agggccgcga gttccccacg      420

caccgctcgg tgctggccgc ctgcagccag tacttcaaga agctgttcac gtcgggcgcc      480

gtggtggacc agcagaacgt gtacgagatc gacttcgtca gcgccgaggc gctcaccgcg      540

ctcatggact tcgcctacac ggccacgctc accgtcagca cagccaacgt gggtgacatc      600

ctcagcgccg cccgcctgct ggagatcccc gccgtgagcc acgtgtgcgc cgacctcctg      660

gaccggcaga tcctggcggc cgacgcgggc gccgacgccg ggcagctgga ccttgtagat      720

caaattgatc agcgcaacct cctccgcgcc aaggagtacc tcgagttctt ccagagcaac      780

cccatgaaca gcctgccccc cgcggccgcc gccgccgctg ccagcttccc gtggtccgcc      840

tttggggcgt ccgatgatga cctggatgcc accaaggagg ccgtggccgc cgctgtggcc      900

gccgtggccg cgggcgactg caacggctta gacttctatg ggccgggccc cccggccgag      960

cggcccccga cgggggacgg ggacgagggc gacagcaacc cgggtctgtg gccagagcgg     1020

gatgaggacg cccccaccgg gggtctcttt ccgccgccgg tggccccgcc ggccgccacg     1080

cagaacggcc actacggccg cggcggagag gaggaggccg cctcgctgtc ggaggcggcc     1140

cccgagccgg gcgactctcc gggcttcctg tcgggagcgg ccgagggcga ggacggggac     1200

gggcccgacg tggacgggct ggcggccagc acgctgctgc agcagatgat gtcatcggtg     1260

ggccgggcgg gggccgcggc gggggacagc gacgaggagt cgcgggccga cgacaagggc     1320

gtcatggact actacctgaa gtacttcagc ggcgcccacg acggcgacgt ctacccggcc     1380

tggtcgcaga aggtggagaa gaagatccga gccaaggcct tccagaagtg ccccatctgc     1440

gagaaggtca tccagggcgc cggcaagctg ccgcgacaca tccgcaccca cacgggcgag     1500

aagccctacg agtgcaacat ctgcaaggtc cgcttcacca ggcaggacaa gctgaaggtg     1560

cacatgcgga agcacacggg cgagaagccg tacctgtgcc agcagtgcgg cgccgccttt     1620

gcccacaact acgacctgaa gaaccacatg cgcgtgcaca cgggcctgcg cccctaccag     1680

tgcgacagct gctgcaagac cttcgtccgc tccgaccacc tgcacagaca cctcaagaaa     1740

gacggctgca acggcgtccc ctcgcgccgc ggccgcaagc cccgcgtccg gggcggggcg     1800

cccgacccca gcccgggggc caccgcgacc cccggcgccc ccgcccagcc cagctccccc     1860

gacgcccggc gcaacggcca ggagaagcac tttaaggacg aggacgagga cgaggacgtg     1920

gccagccccg acggcttggg ccggttgaat gtagcgggcg ccggtggagg aggtgacagc     1980

ggaggtggcc ccggggccgc caccgacggt aacttcacag ccggactcgc ctaaaaacca     2040

aaaagagaaa acagaaaccc gagaaagaga gagacagaga gagagaaaaa aaatcaccca     2100

ccaccccccc aaaaacacaa aaaaagaaaa tctatctata tacagatatc tatatctata     2160

tatatatata cagatatata tatatgacgc gtcacagaat ctagggtagc gctttctcag     2220

atttccctcc tttctgacgt ttttctccct ccgcaggggc cccggccctc cctggctccc     2280

cttcccccca ccaccccatc gctgggtttc ggggcttggt ttggggtttt ttgtaggaca     2340

caaggaatcc gagaccccgc acagccccct gggcacccgg catggggcct ggggcccgat     2400

ccgaggccct gggctggggg gagggtagac gtgggggcgc tgggggggga ctggggtggg     2460

cttttaattt cctcccctcg ctggtttcta tgagtctttc agacaagacc ttaaatgatt     2520

tctgtctgct ctgagcggac gttaaaatgg gcccccgtcc cccgacccgc accctccttc     2580

ctcagggcac ttactaaggg aggggtctcc ctctccatct ccccagtggc ctccccgcct     2640

ccaaccctgc ctgcggcctc cccccgtcgc ccaccccacg tctcctggcc actgagacac     2700

aaacctattt atttctaggc ctggagaaag gagatcggac tggggttccc ggtggggcgc     2760

caggatggct cctgggggtg ctcctgccgc cttccttcac ggcacttaca accggcggga     2820

cccccaggga ccacccctca gggcgccccc ccacccccgc ccggtccacc tagaccccca     2880

cgtttggaga ttcaaaactt ctgtcttcgt cctctccccc gagccccctc tcccaaattt     2940

ttaaagcact ttttagattt ttttttctct ttcctcctta aaaacaaaat ttatatatag     3000

atatatatat atatataaat aatatacttt tcctcagagg agcaggcaac agtgtgggat     3060

aaacagagtc acgatcagag gaaccccagg gtctggtgat ggcagggatg gggggagaga     3120

gagaaaatcc acaaattcca atgtcacaaa agcaataaaa caaactagaa aaaaaaaagg     3180

ttttacaaaa tgaaaggaag gaaaaaaaaa aaggcaacca accacattag aagtcttggc     3240

actttgtaac ggaacgggta ctacacttta tcttaattct taatttaaaa acatgtttac     3300

aagttacaac caacttctat gaaaagttga aaagacaaaa aaaaaaaaaa aaagcgagcg     3360

agagagagag cgagagagag agcgagagca gaagaaattc ctaaaagtcg atttattttt     3420

gtacaaaata ataaaaaaaa aaacccacca caaacgtaga atccacttct gttccccaaa     3480

aagcgagaag gggggttcag gaggaagcca tcgcagggga cctgggagac gccccgaggt     3540

gtttgtgctt cacccccaga cgtcagcctc gaaggcagga ctgtggggtg ttcgtgctgt     3600

gttccccccg ctcccccttt ctgtcccctt ttttggttct gacgtgaaga ggtcttagcg     3660

cccgcttctg tccacggggt ctctccttcc tcctccctag ctcagggatg ggccttccag     3720

ccggagcacc ccgatcccca tccggcaccc cccaatcccc caacacgcct gtccctcccg     3780

catggccacc aaggagctgg accttggatg cgcctaccct gctgaggtgg gtgacagggg     3840

ccccccacct ccagggcctt agaaccaccg cccctctccc caccccaggc acccctcttt     3900

ttactcaaag gcactgactg taatccaggg ggactgggac ctgcctcccc ccaacctctg     3960

gctcccacaa ggcccggtgt tgaccgagcc acaggccacg gacaggggcc ggggttgggg     4020

agactatgtc gccagatgcc aggacgccct caccccgttt gcatatgcaa tgctagcatg     4080

ggaccccgaa aatagacgct ctgctgcact gagacttctt gtcaatgccc aaccggcggg     4140

ggggtgtctc cctgcccccg acccccccat acccccttct ctgtgacaca cacatcttct     4200

cgtctctttt tctttcattg ttaaagggaa gctttttaag aaggcaattt tcatattgtt     4260

tctacaggat ggttttggtt cccttccctt cccacccccc cttaagcctg tcagccccct     4320

ccaaatgtct caggatcccc cctctcccct ggggctgggt gacagcaccc cggctgcgtt     4380

cacaccccag tgtcacaggg cgagctgttc tggagagaaa accatctgtc gtggctgagc     4440

ggggagcttg aacacccagg ccagggacac ccctccccag ctcccagaga ggccccctga     4500

ggggtgagcc ctctttccac cttcccctat ccatgcaccc cctcgcaata aaaccaactc     4560

taaaatcaca gctgtcgtcc tagccagtgg gggcgaccgg acttgggggg tggagccctc     4620

tgggacttcc gtaggaacaa gggctgcggc ccaccgcgac acttacacag acctcgggga     4680

ttgcactaaa ccctcgttcc tagctccgca ctcagcttcg cctgtcctgc ccgcccactt     4740

tgccttaact acccgcccgt cctgggggcc acagcctctg catgggccca gagccgggac     4800

ccccccagcc cagccccgcc ctccccagac tccgcgcaat cacatactgt atatagacgt     4860

gaatcgattt tatttttatt ctttaaatta aggtcgtgat aaagtgttgc caaagatacc     4920

tgctgaattc tcgcgtttca ggaaacaaac aaacaaaaaa aaatgatatt tgaggagggt     4980

cgtgttgact ccatatgaaa ggacacagct caaagctttt ttgtttggtt gtttggggtt     5040

ttttgtgttt tctttttttg gggtgttttt tttttaactg cctggtacaa aaaaaaaaag     5100

agaaaaaaaa aaaagaaaaa caatgcgaaa ttgttatttc cattctcatg gtgaagttgc     5160

gtggacgcgt gtgtgcgtgt gtgcaagaga gcgggagtga ggtccaggct ggggttgggg     5220

ggcttcaggc gggggcgccc gggggccggg gaggtggccg ggccggagcc cccgtctgca     5280

gtgcccccca gcctgccggg cccaggagag agagagaagc atctttgcta ctagctgttg     5340

ctgctacctg cctctgcccc ccgacgcccc ccgccttttg agattaagga aaaaaaaaaa     5400

aagtcaaaaa agtttttaaa aatgaaaaaa aaaaattata aaccagtgaa tgtaaaatgc     5460

cggagcaggc ccggcctggc atgggtgtgg acctgcagcc aggcaggctc gagcgggcga     5520

taccaaagtc tgccccccca ccattgtggc catgcagtcc tgtcactgtc tttttgcttc     5580

cttccgaggg gggtccccca gcctcttcca gggtcttccc ctggaagtgg gcggctgcag     5640

ggaaggtggg ggacaggggt ctttgcacga ttcagacccc ggggccgtgg caggagcggt     5700

cacctcacag gtggtgacac tgaggcaggg gcctcggggt gccccctccc gcccggcaac     5760

cagaatggtt ggaggcaaga cagagagaat gaaaggaaaa acagaagaaa aaaaaatatt     5820

aaaaaccaac aaaaaaagca aaaatcctat tttttgagaa agaaagatat ttatatttgc     5880

agttttattt taaaaagtta tttaagttga agcagccttc ctggaggtgg gggggggggg     5940

gtggtgggtg gctggcgcag gacgggtcag gggcctggag gctgggggtg ccccaggagc     6000

tacaacctca gagttaagac tagctcgcat taaatacata gatttacggg gggggggggg     6060

gggggccggg cccagggggt ggagggggcc agggagaccc ccatccctcg ccggggctgc     6120

ctggaggctg tggaccagga tccgatgccc aggtcccgcc ccccacccca ccccaggccc     6180

agaatcgagg tgccttggac tttggagggg ccaggcctgg tgaatggggg gcggggcggc     6240

gccctcaggg tacagagcac agacagatag acattccaga gactgtattg agagtcttta     6300

taaagtgtgg gagatttaaa aaaaaaaaaa actgataaaa atgcactttt tgggagtggg     6360

gagggagaag ctttaaaagt aataaaaaac aaacaaaaac acaaaagatg aaaaaacaaa     6420

aaaattcatt tttcttgtac ataaaaaaaa aaaaagaacc actaaacgca gcctgttacg     6480

ac                                                                    6482


<210>  2305
<211>  6978
<212>  DNA
<213>  homo sapiens

<400>  2305
gacgccttgg acgcggttca ggaatccgcc gccgctagcc ggctcgggcc tgagcgggga       60

gggcgccagg caggacctct cgcaggctcg ctgcgcagga cggcgcccgc ctggcgccgc      120

ttcccttcca gcgtgccgac cggccccgca gcgcctccat ccctccggcc cgccccggag      180

aagacgcaca gctcgggccg cgcgggcgcc ggggccgcgg aaccgcttct gccgggatct      240

tccaggagga aagcgaagtt gcgagcggat gctgcccgcg ccggacccca gccgcggagg      300

gtcggggccg ccggtggagt ctcggcggcc ggggacaagg gtgtccccca cctgaagacg      360

gcaagctggg tcctgagtga tgcccctcag ctgagtgtcc aaggctggcc cgaggagccc      420

ccacggcccc acctttcccc atggagaaag gactcacttt gccccaggac tgccgggact      480

ttgtgcacag cctgaagatg agaagcaaat acgccctttt cttggttttt gtggtgatag      540

tttttgtctt catcgaaaag gaaaataaaa tcatatcaag ggtctcagac aagctgaagc      600

agattcccca agctctagca gatgccaaca gcaccgaccc agccctgatc ttagctgaga      660

acgcatctct cttgtccctg agcgagctcg attcagcctt ctcccagctt cagagccgtc      720

tccgcaacct cagcttgcag ctgggcgtgg agccagccat ggaggccgca ggggaggaag      780

aggaagagca gagaaaggag gaggagccgc ccagaccggc cgtggcgggg ccccggcgcc      840

acgtgctgct catggccacc acgcgcaccg gctcctcgtt cgtgggcgag ttcttcaacc      900

agcagggcaa catcttctac ctcttcgagc cgctgtggca catcgagcgc acagtgtcct      960

tcgagccggg gggcgccaac gccgcgggct cggccctggt gtaccgcgac gtgctcaagc     1020

agctcttcct gtgcgacctg tacgtgctgg agcacttcat cacgccgctg cccgaggacc     1080

acctgactca gttcatgttc cgccggggct ccagccgctc cctgtgcgag gaccccgtct     1140

gtacgccctt cgtcaagaag gtcttcgaga agtaccactg caagaaccgc cgctgcggcc     1200

ccctcaacgt gacgctggcc gcagaggcct gccgccgcaa ggagcacatg gccctcaagg     1260

cggtgcgcat ccggcagctg gagttcctgc agccgctggc cgaggacccc cgcctggacc     1320

tgcgcgtcat ccagctggtg cgcgaccccc gggccgtgct ggcctcgcgc atggtggcct     1380

tcgccggcaa gtataagacc tggaagaagt ggctggacga cgagggccag gacggcctga     1440

gggaagagga ggtgcagcgg ctgcggggca actgcgagag catccgcctg tccgcggagc     1500

tggggctgcg gcagcccgcc tggctgcggg gccgctacat gctggtgcgc tacgaggacg     1560

tggcacgcgg gccgctgcag aaggcccgcg agatgtaccg cttcgccggc atccccctga     1620

ccccgcaggt ggaagactgg atccaaaaga acacgcaggc ggcccacgac ggcagcggca     1680

tctactccac gcagaagaac tcctcggagc agttcgagaa gtggcgcttc agcatgccct     1740

tcaagctggc ccaggtggtg caggccgcct gcggccctgc catgcgcctc ttcggctaca     1800

aactggcgcg ggacgccgcc gccctcacca accgctcagt cagcctgctg gaggagaggg     1860

gcaccttctg ggtcacgtag gggggccggg gccccgtatg cccctcctcg tgaaaggcct     1920

gccccgtctt tctgccgcag ccctcgcaga gggcgggtgc acagcgccat gagcgggcag     1980

cgcctcctgt agcagtaggg cccccagcca gcgctccagc caaagcggcg gccccagggt     2040

taattgcgga gaacaggaca gtgcccggtc cccttgaggg ccatcacacc cagacccaac     2100

gggttgcagc ctcctgagca ggcctaggca ggcccgggcc tgttggcaag cttcgatctc     2160

acacacacag aaacatacat tcgtgcctgg agaccctgca ggccagagtc caaatattta     2220

acaatcagaa ggggcaaggc tctgaccagt gacagtcaga cctcctgctt tatttggtgt     2280

taaccgtttc ttgtctggat ggtgaagtct ggaatctggg tgggtccttg gaggaggggc     2340

taggacagcc gtgggtgtca aaggtggcat ttgaggctcg tttgaggtga cagtggctgt     2400

ttaccaacta gtacagagcg attcagcgtt ttcatgaatg ggttggctgt gctggttact     2460

gatgaatatg ggccccttat agagctgcaa aacacacaca tgcgtataga catacataca     2520

tgtacaccat acatagacaa gcatcataaa ggcacaagtg cacacacatc tatgcagaca     2580

agcttcctcg ctgcttatgc ccacagggtt tttctgtatg acacacctca gaggagcctg     2640

tgcttaacat ttgtaggatt atttcgaggg cagggcaggg gaaagaaacg cgttaaaggg     2700

ccatgacatg acacagttcc ctggccgggt ttggactgaa cagtggattc agaactgcag     2760

cgttcaaagc ccctgcccgc cttagattct catggctacc tcctctgacc catccacatc     2820

cttgcggctg gcaggcagga tgttttgaaa tggtgcagcc aaaggccccg tctagcttgg     2880

ctggctcccg aacatgtcca tatttgaagg ctgcctcagg cctggcaggc agaagcagct     2940

gtggtccctg gaggcaaaag gcagctcacg gggccttcca tttccagcca ggcctcatct     3000

ggggtagggc caagaggaaa gtacagagtg cccgtggggg agaagtccca ccaggatgcc     3060

ccccctcccc tgagaagccc gccttctccc tcgtggacag gagtcagcca gttggttgct     3120

gtggttacag ccagtgcctg gaattcctcc ttagggccct gggaagagta ttgcttaacg     3180

caggatgtgc tgggtgtttt gtttcgggct tttatttatg gcttggtgtc tttcttgttt     3240

catggctgtg tttttgcttt tgtttctgta ggagcgcctc ttccaagcag tggaggcctg     3300

agggcttgag ggaggctggg gaaaaccagc agggagcact tggctcctgg cagagggaga     3360

ggacaggagg aggagccttc cccaggagga acgaggagag gtggccacgt ggcaggccac     3420

agtgccctat gggcttttct gtttgaaccc catgtgggat gaatctcaaa gccaccagcg     3480

ttcttgccta gtgtccagag cagcagagat ttgcagccct cgcccctccc tgagaagaag     3540

ctggatttga aaatccctca caggccctaa catgtttcct gggtgggcag gggcctcatg     3600

acaagcgaca agtgtaccca gagtagaagg ccttccccac tcccacctca aacccaggag     3660

cagaactcag tatccagagc ttacaaggag ctgcaagggt ttgccgaggg ctgcccagct     3720

ctgcttctgg tttcctggac aatttctctg tcagatacgg cccattgtaa acccagaggg     3780

ctgcattttg ggttgagtaa tatggacacc atggaagtac aggatctgag tccaacattg     3840

ccatggggga gggaagagtg tgtcctggca ggaagccacc attggagaag gtgaggccag     3900

taaccatctc atgggattcg ctataatcag cctatttgag ctgctgggtc tctgtcactg     3960

tggactccag tcattcaagg aggtctccac tcttgggttt tttttatttt cttttctttt     4020

gctattttgc ctgaacaccc caacactctt ggttttagag tccaagagta agttgtgcag     4080

agacatggtt ctaatttgga gttcaaagga acaccagctc tgaaaacatg accgtggggc     4140

caggatgttt ctggcaggcc cagaagtgct ggccgttctt ccccagcctc cccactgctc     4200

cctcctctgt tccccatgtg gaggtcggag gggctgggac tggggagggg gcagccacct     4260

ccatccaagg ctcttcctag gggccctgct aatgtggaca gtagacttta tccctccttc     4320

ttactctggg ccaagacctc ccactccgcc ctctgaggat ggtaccaaga atgggccttt     4380

gggacttctc aggacattga caatgtgcac actgcaggtt gacttaattt atttattttt     4440

tgaaaagaag agacagaaaa taccttatta tctgcaggga ctcaaagctg tacccaaatc     4500

aagaaagaca aaataacaat agaaaccatt cacacactcc gttcatgcat ggacaccaga     4560

agacgattca gaacacaaga ggagaatgag ctggagcgcc agcaccacga tggccccagg     4620

acgttgttta agatctgaga tcccttggtt tctctcttgt tgatctgaga tgctacatca     4680

gggcccttgc tgctgtatta cctctgcccg ggtgtttgag acaggtcaca agcgcgtgga     4740

tgtttcctgg aagtgtattc ccctggggct cagcgatgct ctgggaaccc ttggggtttg     4800

gggaaggaca gtgtggtgtg actattggct tgaaacgtta tggatatggt tggagtcacc     4860

catgtggata tgattttcag cttggagctg ggatggagaa gatggaagca ctggtggccg     4920

ggcctctttt tccagcgagg ccagccctgg cttctcctct gttccagctt gtctgccaga     4980

agccttcccc tgcaaggtgc ccacctgccc ggagacagag ggagcagctg aggcctctct     5040

ccactggccg ccagcctccc tagcacaagg ggaccattca gcaatgagtg tttactcatg     5100

ttctttcttg ttgatgagtt ctgcggccca gcatatagaa atggctcaga acgttccagg     5160

ccttggtgag acacagcagc gtccaatgct cacaggctgt ccccactctg cctgttccca     5220

tcttcccctc gggacctgtt tataaattga ggaatggatg agggccctgg agggtccttg     5280

ggagtagtta gtggagggca ggattctcag gtccccatag agagggaaag agaagaccag     5340

atgtgcatag aagccagtct ctgtcacata caccgcaggt ggtcaccgag ttattttcca     5400

aaagctgagg aacataaagc aaatttaggc ttttgtcctt ctgcaataca tgcacttgaa     5460

aataaacaga aaagagatgt ttaataacaa gtttacttcc ggtctgctag caccctcagc     5520

ctgggagcta ctgccagagg ctggcgtagt ggggcagctg ctgaccaaac cccacagaac     5580

agagggcacc aggcatcaca cgacatcttt ccctcccatc tctgccatct gtctgtctgg     5640

caatggaagg agcttcagca ggaggtcctt cccagaaggt tgattcttgg cctgggtggt     5700

agaggagata tcctgaccct aaagtcttcc agccccgggt catcctctcc tatactaggg     5760

cctattgacc gtagaggcca ggtgcggtgg ctcatacctg taatcccagc agttggggag     5820

gccaaggtgg gaggattgct tgagcccaag agttggagac cagcctgggc aacatggtga     5880

gaccaattga ctgtagggct tgtcccttgc taagacagga gcagaagact ggatggctgt     5940

gtcctcaagg cagtcccctc ccatccccat tcccaaagtc agaaagtgaa gccagatctc     6000

aagggctgat acctgaggca aggagagcta aggggagaga aattggggct gagtggaagc     6060

agatgcctgc acaagccaag tgtgtcttat tgatctgtac aagctgatag aaggaccatc     6120

tgctgaaatc cagggctcct gagttggtgg gtttgcttgt gaagcttcta ggacaaggcg     6180

cagccagatg gaagggagag ggtccagggc ttcctaaatg cagccgcatc acctgtcaac     6240

tcgctgcagt ttcagagaca gtggaagctg ctctttacct caaaagcaca aagcagaatt     6300

ggcaacttca cttgtctcaa gagctccaag atcctttggt ctcgtgtcct ttggcacccc     6360

gtaactggac tggggacaaa tttgttacgt gtttccaagg ctacagacat ggcgccatcc     6420

tcacaggcct agctcatgtc atggatcagg tgctttgctg gggggataca atgacccatg     6480

tggtctgcgt cttctgccat tggcttgaac tgggcacccc ctgaagtctc catctcagct     6540

gtatattcta gtccaaattt tcctggctcc cctgctccct cccaggtcct gcacactgtc     6600

tttttgccaa cacctcagcc ctgtttgcta tttcatgtct gcatggtacg agacacccct     6660

tcacggcata cactgccatg gtatgtacat atgcatccac gtgtgtgtat gtgtagcatg     6720

tagctcattc tgctcagcct ctggcgccgt tccacattgc tcccagcccc attgctgtca     6780

ctgtcgtccc agatgtcctt gccatggcca cagacaatct gccgtctcct ggaaacgctg     6840

gggctgccct tcagagagct ggcagcccca gcagtcaggg cctgctttgc agaatagaat     6900

gtgaacccaa ctcctgatgg cctacttgac ttatttaatt aaagatgaaa tcatgcaatg     6960

agcaaaacct gcaaaaaa                                                   6978


<210>  2306
<211>  3712
<212>  DNA
<213>  homo sapiens

<400>  2306
gggtgctccg ccctccccgc aggcggcgtg cggctgcata gcctgagaat cccggtggtg       60

agcggggatg gcggttgtag cggcggctgc cggctggcta ctcaggctca gggcggcagg      120

ggctgagggg cactggcgtc ggcttcctgg cgcggggctg gcgcggggct ttttgcaccc      180

cgccgcgact gtcgaggatg cggcccagag gcggcaggtg gctcatttta ctttccagcc      240

agatccggag ccccgggagt acgggcaaac tcagaaaatg aatcttttcc agtctgtaac      300

aagtgccttg gataactcat tggccaaaga tcctactgca gtaatatttg gtgaagatgt      360

tgcctttggt ggagtcttta gatgcactgt tggcttgcga gacaaatatg gaaaagatag      420

agtttttaat accccattgt gtgaacaagg aattgttgga tttggaatcg gaattgcggt      480

cactggagct actgccattg cggaaattca gtttgcagat tatattttcc ctgcatttga      540

tcagattgtt aatgaagctg ccaagtatcg ctatcgctct ggggatcttt ttaactgtgg      600

aagcctcact atccggtccc cttggggctg tgttggtcat ggggctctct atcattctca      660

gagtcctgaa gcattttttg cccattgccc aggaatcaag gtggttatac ccagaagccc      720

tttccaggcc aaaggacttc ttttgtcatg catagaggat aaaaatcctt gtatattttt      780

tgaacctaaa atactttaca gggcagcagc ggaagaagtc cctatagaac catacaacat      840

cccactgtcc caggccgaag tcatacagga agggagtgat gttactctag ttgcctgggg      900

cactcaggtt catgtgatcc gagaggtagc ttccatggca aaagaaaagc ttggagtgtc      960

ttgtgaagtc attgatctga ggactataat accttgggat gtggacacaa tttgtaagtc     1020

tgtgatcaaa acagggcgac tgctaatcag tcacgaggct cccttgacag gcggctttgc     1080

atcggaaatc agctctacag ttcaggagga atgtttcttg aacctagagg ctcctatatc     1140

aagagtatgt ggttatgaca caccatttcc tcacattttt gaaccattct acatcccaga     1200

caaatggaag tgttatgatg cccttcgaaa aatgatcaac tattgaccat ataggtaggt     1260

atgcatcttg agaaagctac tatgtgcccc tgacattaac gtactgttaa ccaagacaca     1320

gcaatcatca gtgttttgat ggtaacaaac tttgatggta aagttggtaa aaggcaactt     1380

tcagaagaaa ataatgtgct ttagaaaaaa aattcaaatt tatagtagta tatttacatt     1440

tttgttgttg ttgttgttct gagatggagt ctcactctgt cgcccaggct agactgcagt     1500

ggtgcaatct cagctcactg caacctcccc cctacccctg agttcaagcg attctcctgc     1560

ctcagcctgc tgagtagttg ggattacagg cgcccaccac catgcccagc taatttttgt     1620

gtttttattg gaggtggggt gtcactatgt tggctcagct gatttcaaat tcctgacctc     1680

aagtgatcca cctgccttag cctcccaaag tgctgggatt acaggcatga gccactgcac     1740

ctggctatat ttacatttaa tagaaacata tctagcatat gtatatgtga tttttttttt     1800

ttttttgaga ccgagtctca ctctgtcacc aggctggagt gcagtggtgc gatcttggct     1860

catggcaacc tctgcctccc aggttcaagc gattgtcctg cctcagtctc ctgagtagct     1920

gggactacag gtgtgcacca acatgcccag ctaatttttt atatttttag tagagacggg     1980

gtttcaccat gttggccagg atggtctcga tctcttgacc ttgtgttcca cccgccttgg     2040

cctcccaaag tgctggaatt acaggcatga gccaccgcgc ctggcctgta tatgtgattt     2100

ctaaaaaata gatgcatgca tatgttaaca ttgaatagtc aatcactaga tgaagatgct     2160

ctctaccatg gtttagattg caagtgtact ttataccatt gtttcaactt caacctttat     2220

ttttgtatat attttttcag ctacttaaac tgttcatgaa taggcgtact ttctgtattt     2280

aaaaatggcc cctcaagcac cgttaattta cattccagtt atttacatga taattcatga     2340

cattctgaaa cttgcctgta tattatctga aaaatggatt tcttgagcaa aagatctgtt     2400

tattgtatgt aaggaaaaat tttacctgaa aacaaacaaa caaaccctaa aactcagcac     2460

cactaccatt tccagaagct tttttaacaa gtgaatattt tttacataat ggataataaa     2520

tggtatttat tcatcatgat tttctaagta atgcttatca gccccttcag tggtgttatt     2580

ctaacaaaat gaatacatta caaattatta agttagcttt tcagagtttt aatatagaag     2640

ttactagcac tgacacactg attttgaaat gtttcaaaat gagtagatat gattagatcc     2700

tttacctttt aatatctagt ttttccaaaa atgatagtaa tatcttttga agaactatgc     2760

tttttcaaaa gcaaaatcaa ctctgtataa tagcacattc tctacttttt aaagatcaga     2820

aatgctagaa ttcttgactt ttgtgtatgg gtagtaaatc tagctcactg aaaatcagag     2880

tgaaacgcct ttacatttgt gcggatagag aagttaactc tccctcatat gtcactgtgc     2940

taccataatc cctacatttt ctgtctgttc tagtctaaga atattgttat agatggaagt     3000

taggaccatt agcccacaga tgcatgtatt ctctcagaca taccggtgta gatgctatat     3060

ttctgatgtc ttcttaatgt ctgtgaaagc aactggcatc tacaataaat cacacttaga     3120

gctggttaga ggactccttc acttttgttg tccatgtggt tcccttccgt ggaccagccg     3180

taataaagag ccaaggtagt gatggtggcc acgtgcctcg ttgctatttt taaagtaata     3240

ttcagatgtg gttttaaatt tagattatgt attccttttg aaacataaga aaaacattta     3300

aacctatgct gaaaatacga taaaagaaaa acaactccaa tatgctaaaa gttaaatatg     3360

gtatttaaga aaatagtcat gtatgcaatt gagaaagtct ataatttatt ttacagaaaa     3420

gctggaagat tatgactaga tatggaaata ttttttctga attttttttt atatttcctc     3480

cgacttacct ctttttgaaa agagagtttt tattaagtga accatcacga tattggctga     3540

aaagttctac attctattat tgtattgtaa cacacatgta ttgatgattt tcattaagag     3600

tttcagatta actttgaaaa atattccaca tggtaatctt ataaattctg tttaattaca     3660

tctgtaaata ttatgtgtgt gatagtattc aataaagtaa aatcaaattg tc             3712


<210>  2307
<211>  2358
<212>  DNA
<213>  homo sapiens

<400>  2307
tttttttttt ttttttgctt aaaaaaaagc catgacggct ctcccacaat tcatcttccc       60

tgcgccatct ttgtattatt tctaatttat tttggatgtc aaaaggcact gatgaagata      120

ttttctctgg agtctccttc tttctaaccc ggctctcccg atgtgaaccg agccgtcgtc      180

cgcccgccgc cgccgccgcc gccgccgccg cccgccccgc agcccaccat gtctcgccgc      240

aagcaaggca aaccccagca cttaagcaaa cgggaattct cgcccgagcc tcttgaagcc      300

attcttacag atgatgaacc agaccacggc ccgttgggag ctccagaagg ggatcatgac      360

ctcctcacct gtgggcagtg ccagatgaac ttcccattgg gggacattct tatttttatc      420

gagcacaaac ggaaacaatg caatggcagc ctctgcttag aaaaagctgt ggataagcca      480

ccttcccctt caccaatcga gatgaaaaaa gcatccaatc ccgtggaggt tggcatccag      540

gtcacgccag aggatgacga ttgtttatca acgtcatcta gaggaatttg ccccaaacag      600

gaacacatag cagataaact tctgcactgg aggggcctct cctcccctcg ttctgcacat      660

ggagctctaa tccccacgcc tgggatgagt gcagaatatg ccccgcaggg tatttgtaaa      720

gatgagccca gcagctacac atgtacaact tgcaaacagc cattcaccag tgcatggttt      780

ctcttgcaac acgcacagaa cactcatgga ttaagaatct acttagaaag cgaacacgga      840

agtcccctga ccccgcgggt tcttcacaca cccccattcg gcgtagtacc cagagagctc      900

aagatgtgtg gcagttttcg gatggaagct cgagagccct taagttctga gaaaatttga      960

agcccccagg ggtggggtgg acgcgtgccg cccagtcgac gtcagcgtgg tctgtcatcc     1020

tgctagtttg tgatgttttc tgacagtagc ctccaagaag ccgttgtgcg aagacagagt     1080

cctgcagagt ccttccagcc taggcctgca gcgccatttt atttatattt tttaataaaa     1140

agtaaaaaca aaaaaacaga cccacattgg aacagtgaat cagtcccata gagagggccc     1200

gtggaccatc gctgtcatga gtgatgccct ggcccttctg aaaccagcca acctaattac     1260

ctgtattgtg gaaatgcgca tgagtcccca accccttgtt tctatacatt ctatgttgtc     1320

ttttaaaaag tgtgcttaac attgacacaa taaatgttgg agctttaggt ggtgtttgct     1380

tgttctttaa tttttaatgc ttataagaca atgaggctgc ttatgatttt gtacttctgt     1440

acctgtttcc tacagacacc catcgggtgg gtaggaggaa cagatttgag aaatgggcag     1500

gagatgtagg aggggaacta ggttaccgct tatcagatgg cataaatttt caaggagaat     1560

caaaatgcaa aacttgggaa taaatcatag caatatcata attaatgtag tagtaatatt     1620

gctgtttatt aatgctgaag tgtggttttc ctaactgtct gacttataat ttgcatacca     1680

ttaaataatg cataatatgg cacgccgaat cctgtttttc aaatatatgc ttttggtggc     1740

taccatgcag gatttgaatt tgtcttttaa tttagcttag gaaagaacat cactgggcga     1800

gcggtaaatc ctaaagaagg tgataaatgt cagtagtttc ttattaaata ttctaatttt     1860

aggttcccaa accttcagga aatatatctt aatgcagaca aacaaacata aaacttcttt     1920

agtacttaca tcaggaaatt tggggcagat tttagagggg ggaaattata ggaggaaaga     1980

agttcacatc agaacagaca atcacagcaa tgctctattc cttagaaatt agtgccacaa     2040

ataagttaca tctacaaaca ggtggtaaaa attctttctg gcccagttaa tttgcacaga     2100

acttttctca gtttggtatt ttttactgct tggagatcca gaagagaatt agaaacaaca     2160

tagcaaatta aaataggttt gtcaataata gagctcagac acctgtgtgc tgtagattca     2220

catacaggcc gtgaacctaa gtggggaaaa tcctacctat ccaccttctg gctagattac     2280

ctagcttagt gaaaagatag ccaaataatt ggcatgtgaa ttatttcctg cttattcata     2340

ataaataatg actgtcta                                                   2358


<210>  2308
<211>  3958
<212>  DNA
<213>  homo sapiens

<400>  2308
tttttttttt ttttttgctt aaaaaaaagc catgacggct ctcccacaat tcatcttccc       60

tgcgccatct ttgtattatt tctaatttat tttggatgtc aaaaggcact gatgaagata      120

ttttctctgg agtctccttc tttctaaccc ggctctcccg atgtgaaccg agccgtcgtc      180

cgcccgccgc cgccgccgcc gccgccgccg cccgccccgc agcccaccat gtctcgccgc      240

aagcaaggca aaccccagca cttaagcaaa cgggaattct cgcccgagcc tcttgaagcc      300

attcttacag atgatgaacc agaccacggc ccgttgggag ctccagaagg ggatcatgac      360

ctcctcacct gtgggcagtg ccagatgaac ttcccattgg gggacattct tatttttatc      420

gagcacaaac ggaaacaatg caatggcagc ctctgcttag aaaaagctgt ggataagcca      480

ccttcccctt caccaatcga gatgaaaaaa gcatccaatc ccgtggaggt tggcatccag      540

gtcacgccag aggatgacga ttgtttatca acgtcatcta gaggaatttg ccccaaacag      600

gaacacatag cagataaact tctgcactgg aggggcctct cctcccctcg ttctgcacat      660

ggagctctaa tccccacgcc tgggatgagt gcagaatatg ccccgcaggg tatttgtaaa      720

gatgagccca gcagctacac atgtacaact tgcaaacagc cattcaccag tgcatggttt      780

ctcttgcaac acgcacagaa cactcatgga ttaagaatct acttagaaag cgaacacgga      840

agtcccctga ccccgcgggt tggtatccct tcaggactag gtgcagaatg tccttcccag      900

ccacctctcc atgggattca tattgcagac aataacccct ttaacctgct aagaatacca      960

ggatcagtat cgagagaggc ttccggcctg gcagaagggc gctttccacc cactcccccc     1020

ctgtttagtc caccaccgag acatcacttg gacccccacc gcatagagcg cctgggggcg     1080

gaagagatgg ccctggccac ccatcacccg agtgcctttg acagggtgct gcggttgaat     1140

ccaatggcta tggagcctcc cgccatggat ttctctagga gacttagaga gctggcaggg     1200

aacacgtcta gcccaccgct gtccccaggc cggcccagcc ctatgcaaag gttactgcaa     1260

ccattccagc caggtagcaa gccgcccttc ctggcgacgc cccccctccc tcctctgcaa     1320

tccgcccctc ctccctccca gcccccggtc aagtccaagt catgcgagtt ctgcggcaag     1380

acgttcaaat ttcagagcaa cctggtggtg caccggcgca gccacacggg cgagaagccc     1440

tacaagtgca acctgtgcga ccacgcgtgc acccaggcca gcaagctgaa gcgccacatg     1500

aagacgcaca tgcacaaatc gtcccccatg acggtcaagt ccgacgacgg tctctccacc     1560

gccagctccc cggaacccgg caccagcgac ttggtgggca gcgccagcag cgcgctcaag     1620

tccgtggtgg ccaagttcaa gagcgagaac gaccccaacc tgatcccgga gaacggggac     1680

gaggaggaag aggaggacga cgaggaagag gaagaagagg aggaagagga ggaggaggag     1740

ctgacggaga gcgagagggt ggactacggc ttcgggctga gcctggaggc ggcgcgccac     1800

cacgagaaca gctcgcgggg cgcggtcgtg ggcgtgggcg acgagagccg cgccctgccc     1860

gacgtcatgc agggcatggt gctcagctcc atgcagcact tcagcgaggc cttccaccag     1920

gtcctgggcg agaagcataa gcgcggccac ctggccgagg ccgagggcca cagggacact     1980

tgcgacgaag actcggtggc cggcgagtcg gaccgcatag acgatggcac tgttaatggc     2040

cgcggctgct ccccgggcga gtcggcctcg gggggcctgt ccaaaaagct gctgctgggc     2100

agccccagct cgctgagccc cttctctaag cgcatcaagc tcgagaagga gttcgacctg     2160

cccccggccg cgatgcccaa cacggagaac gtgtactcgc agtggctcgc cggctacgcg     2220

gcctccaggc agctcaaaga tcccttcctt agcttcggag actccagaca atcgcctttt     2280

gcctcctcgt cggagcactc ctcggagaac gggagtttgc gcttctccac accgcccggg     2340

gagctggacg gagggatctc ggggcgcagc ggcacgggaa gtggagggag cacgccccat     2400

attagtggtc cgggcccggg caggcccagc tcaaaagagg gcagacgcag cgacacttgt     2460

tcttcacaca cccccattcg gcgtagtacc cagagagctc aagatgtgtg gcagttttcg     2520

gatggaagct cgagagccct taagttctga gaaaatttga agcccccagg ggtggggtgg     2580

acgcgtgccg cccagtcgac gtcagcgtgg tctgtcatcc tgctagtttg tgatgttttc     2640

tgacagtagc ctccaagaag ccgttgtgcg aagacagagt cctgcagagt ccttccagcc     2700

taggcctgca gcgccatttt atttatattt tttaataaaa agtaaaaaca aaaaaacaga     2760

cccacattgg aacagtgaat cagtcccata gagagggccc gtggaccatc gctgtcatga     2820

gtgatgccct ggcccttctg aaaccagcca acctaattac ctgtattgtg gaaatgcgca     2880

tgagtcccca accccttgtt tctatacatt ctatgttgtc ttttaaaaag tgtgcttaac     2940

attgacacaa taaatgttgg agctttaggt ggtgtttgct tgttctttaa tttttaatgc     3000

ttataagaca atgaggctgc ttatgatttt gtacttctgt acctgtttcc tacagacacc     3060

catcgggtgg gtaggaggaa cagatttgag aaatgggcag gagatgtagg aggggaacta     3120

ggttaccgct tatcagatgg cataaatttt caaggagaat caaaatgcaa aacttgggaa     3180

taaatcatag caatatcata attaatgtag tagtaatatt gctgtttatt aatgctgaag     3240

tgtggttttc ctaactgtct gacttataat ttgcatacca ttaaataatg cataatatgg     3300

cacgccgaat cctgtttttc aaatatatgc ttttggtggc taccatgcag gatttgaatt     3360

tgtcttttaa tttagcttag gaaagaacat cactgggcga gcggtaaatc ctaaagaagg     3420

tgataaatgt cagtagtttc ttattaaata ttctaatttt aggttcccaa accttcagga     3480

aatatatctt aatgcagaca aacaaacata aaacttcttt agtacttaca tcaggaaatt     3540

tggggcagat tttagagggg ggaaattata ggaggaaaga agttcacatc agaacagaca     3600

atcacagcaa tgctctattc cttagaaatt agtgccacaa ataagttaca tctacaaaca     3660

ggtggtaaaa attctttctg gcccagttaa tttgcacaga acttttctca gtttggtatt     3720

ttttactgct tggagatcca gaagagaatt agaaacaaca tagcaaatta aaataggttt     3780

gtcaataata gagctcagac acctgtgtgc tgtagattca catacaggcc gtgaacctaa     3840

gtggggaaaa tcctacctat ccaccttctg gctagattac ctagcttagt gaaaagatag     3900

ccaaataatt ggcatgtgaa ttatttcctg cttattcata ataaataatg actgtcta       3958


<210>  2309
<211>  5265
<212>  DNA
<213>  homo sapiens

<400>  2309
acgcgggcgg gtgccgaggg gaggggagtg gcggcggcgg cgggcggctc ccgcttcagc       60

ctcggcagtg gcgtcggcga cggcggtgtc gaggcagccg ccagcgttcg gccaagtgtc      120

agccggcagc gacggcgcta gagctgggag ctggggacgc gcgcgccgga ccttccacag      180

cctccgccca gagcctgagg cgccggggcc gggggagccg gggggcgggc gggcgagcgg      240

gccgggggga gggtggggga tggcgcggac cctgcggccg tccccgctgt gtcctggagg      300

cggcaaagca caactttcct ccgcttctct cctcggagcc gggctcctgc tgcagccccc      360

gacgccacct ccgctgctgc tgctgctctt cccgctgctg ctcttctcca ggctctgtgg      420

tgccttagct ggaccaatta ttgtggagcc acatgtcaca gcagtatggg gaaagaatgt      480

ttcattaaag tgtttaattg aagtaaatga aaccataaca cagatttcat gggagaagat      540

acatggcaaa agttcacaga ctgttgcagt tcaccatccc caatatggat tctctgttca      600

aggagaatat cagggaagag tcttgtttaa aaattactca cttaatgatg caacaattac      660

tctgcataac ataggattct ctgattctgg aaaatacatc tgcaaagctg ttacattccc      720

gcttggaaat gcccagtcct ctacaactgt aactgtgtta gttgaaccca ctgtgagcct      780

gataaaaggg ccagattctt taattgatgg aggaaatgaa acagtagcag ccatttgcat      840

cgcagccact ggaaaacccg ttgcacatat tgactgggaa ggtgatcttg gtgaaatgga      900

atccactaca acttcttttc caaatgaaac ggcaacgatt atcagccagt acaagctatt      960

tccaaccaga tttgctagag gaaggcgaat tacttgtgtt gtaaaacatc cagccttgga     1020

aaaggacatc cgatactctt tcatattaga catacagtat gctcctgaag tttcggtaac     1080

aggatatgat ggaaattggt ttgtaggaag aaaaggtgtt aatctcaaat gtaatgctga     1140

tgcaaatcca ccacccttca aatctgtgtg gagcaggttg gatggacaat ggcctgatgg     1200

tttattggct tcagacaata ctcttcattt tgtccatcca ttgactttca attattctgg     1260

tgtttatatc tgtaaagtga ccaattccct tggtcaaaga agtgaccaaa aagtcatcta     1320

catttcagat cctcctacta ctaccaccct tcagcctaca attcagtggc atccctcaac     1380

tgctgacatc gaggatctag caacagaacc taaaaaattg cccttcccat tgtcaacttt     1440

ggcaacaatt aaggatgaca caattgccac gatcattgct agtgtagtgg gtggggctct     1500

cttcatagta cttgtaagtg ttttggctgg aatattctgc tataggagaa gacggacgtt     1560

tcgtggagac tactttgcca agaactacat tccaccatca gatatgcaaa aagaatcaca     1620

aatagatgtt cttcaacaag atgagcttga ttcttaccca gacagtgtaa aaaaagaaaa     1680

caaaaatcca gtgaacaatc taatacgtaa agactattta gaagagcctg aaaaaactca     1740

gtggaacaat gtagaaaatc tcaataggtt tgaaagacca atggattatt atgaagatct     1800

aaaaatggga atgaagtttg tcagtgatga acattatgat gaaaacgaag atgacttagt     1860

ttcacatgta gatggttccg taatttccag gagggagtgg tatgtttagc aaccactgaa     1920

tgtgacttaa ctatgtacaa tgttcattca cactagttga tcattttcag attgttcata     1980

ctttttcttg aggaagaata agctttttca agttgatttt caagcttact ttttatattc     2040

taatctgaca aatgaaaatg taaaatctga gttcagtgta tctaagctgc tttacaattt     2100

tttttcaatg ctgtactact gtctcaagat ttaaatttta atgcagagta ctttattggt     2160

gtgaggcaca caggtaagaa gaaatgtcaa cattaaatgt atgacttact tggtacaaaa     2220

attttttaaa aagggaacta ccttgacatt gtgtattaaa tgtttaccta agactataat     2280

ctcaagtatg atgtttgttt aacatatacc tctcaaaatt tatcaccact caatgacact     2340

gcatcaaaat tgactataaa actaattcaa gaaatattta tatatatttt ttaatataca     2400

aaaaatattt agcctgatgg aatggctttc cttttcaaac attattttct aagtttctat     2460

acaaatgaaa tctttacctc tgcatattaa tgagccttgc cataattact gtagagtggc     2520

ttttcaaaga tattttgttg cactaaaact gtggtagtaa actcagtgaa catgatgtgt     2580

ggaagagcat aattagctgg tcaatatttt tgtccaaaat acctgcaaga gtaataaaat     2640

acataccttt caaacatgat aattattagt tttttttttt cctttctgga acatggattt     2700

tggtacatta gcagtagcct tattttaatg ctttatgtcc taaacatact aatagaaatg     2760

aaaagacgca gagagagcat ttcggaatac tgaagtacta gttttagaaa tgagactttc     2820

agccaacaat ctatagaaag aattttatgg accatcttgt tttagttatt taatgttgat     2880

gttgttcaaa tgggtaaatg tacagaaaga aaattttaga gtaaacttgg aactttggat     2940

ataactagaa aaaactagat tatagaatta gtcggtaaca cttgctaatg gacattggca     3000

ttcatctcct ttttcctcct aagtgtatgt atgtgtttta agatttctgt ttttacgatt     3060

aaaactggaa acatgaggtt ttttgttttt gtttttttac ataattacat atattccttc     3120

tgaatcattt atcttttgag aaagaaatgt tacctaaact tcaaatgtgc tttttgtttg     3180

tgaggtaatt aaattgcttc tacagtggag gcttacaaaa ttattgtgac aactattttg     3240

aagctgaaag gatagttttt ctattgctaa gtcatttgaa aaagtgacca ttttgccagt     3300

gaaatgaagt ggaagttagt aggagaatca taaattaaat atattatttt gttaataaaa     3360

aggcaaagta gtaggtactt tttaaaccct cccaaccagc cctttctcaa tattcatcaa     3420

atctaaaaca tttagggggc aaaattctaa catgttcatg gtatcttgca aatagtgaaa     3480

gctttattct gaaggattat aaactagttt tcttcatttt aactagcact attttgtgga     3540

aattagaaac ctcttttatt tctcttccca aaagtaatac ttattataag gctgtagtat     3600

caggttaagg atacagataa ataaagttca cttatatctt cttacaaatg tctgggtttt     3660

aatatggtta atcacttata tacaaatatt acaacttttt agtgcaagtt tttggaagaa     3720

aactttttga taaaacactg tgattgatgt gactttattt ttaatttaaa cgatgaggtg     3780

gccagaagaa agatgggtct aaaatttctc cccatgaaag atgtaaaact atggcttttt     3840

ttaaaatcaa aatttcatct tttaaaataa tggtttgaaa tactgtatgg atctgaacag     3900

aataatcaca tttaggattc tatataaatc tcaactggag tataatctga aggaaattag     3960

cagtgtattt taagaaatat atttcaaaaa tataaatact gattatgaac ttccttttac     4020

attgtggtta tttgtgcgat taggtttttt tgtttgtttc ttttgtgttt gtttggcggg     4080

agagggtgac ctggaaagcc acaagtgagt atttgacata ttctgtatcc ttaatccaat     4140

catttggcaa actaaaaggt ttctgtgttg taagaatctg atactagtgc ttaagacttt     4200

gggaagcatt gcactgttgt ttattagaac tttatgtata tttactgtac atagagactt     4260

gtttgaaaac atgaatagtc attaaataaa gacattgtta aattagtttt tgaataccag     4320

tgatattcat aactacttga caggtatata tgaaaattct actatcgtga aaaaaaatga     4380

atatttgtac tatttttggc catatttata tttatttctt tcatatggtt tgaactgttt     4440

tagcattttg taaattcact tgagagtttt ctttcatact ggttaaaata tttcaatgat     4500

ataatgaaga tgaatgcaac tcttattttt ctgccatttt ttattaaaat acattgaaac     4560

taaagtaggc tcggggttaa ctttaaaagt gatatttgag aagtgcttta gagttgaaag     4620

atttagtatt ttaccacgtg cctagtaggg ttctatttgc taactctaat attgaggaaa     4680

ctattaaggt tttcagtagt aagtgttgct tctaatagcc atatacagga aagttttata     4740

agataaccca cggctaaata ttttgcatta aggagctgta ggagtacagt gtataagtac     4800

agaaattgag agaaatgtag tcattttata tgtgaaaaca tctgatttga gtttttgata     4860

aatactgcta aaacacagta tatgaacaag taagaagttt atgtatgaaa gtaatcaatg     4920

taaaatataa gaaaggaata aatggtaccc attttgaatt tttaattcta ataggagagt     4980

agattgtaga ttgaattgtc tttcctgttt acttgttaat tagaaaatgc atccttcata     5040

aacagctcct ttctcaaatt ttttgtatat tgtgtttgtg tttgggtttt agtttgtacc     5100

cgcgctaagt tttggttttg ttgtgtttgg tgttttttgt tttgttttgt tttgttttgt     5160

tttttctttt ttaaccaacc tgtgtattag gtgttagccc caatagccat gcatgaaatc     5220

tttaaataaa agttaaaaaa gttctttaga ggcaaaaaaa aaaaa                     5265


<210>  2310
<211>  2741
<212>  DNA
<213>  homo sapiens

<400>  2310
ccagccaggg gttcccggtt tcacagagag gaaagtgaca gaagacgtgc ggagggagac       60

gcagagacag aggagaggcc ggcagccacc cagtctcggg ggagcactta gctcccccgc      120

cccggctccc accctgtccg gggggctcct gaagccctca gccccaaccc cgggctcccc      180

atggaagcca gctgtgcccc aggaggagca ggaggaggtg gagtcggctg aatgcccacg      240

gtgcgcccgg ggcccctgag cccatcccgc tcctagccgc tgccctaagg cccccgcgcg      300

ccccgcgccc cccacccggg gccgcgccgc ctccgtccgc ccctcccccg gggcttcgcc      360

ccggacctgc cccccgcccg tttgccagcg ctcaggcagg agctctggac tgggcgcgcc      420

gccgccctgg agtgagggaa gcccagtgga agggggtccc gggagccggc tgcgatggac      480

gccgtcttgg aacccttccc ggccgacagg ctgttccccg gatccagctt cctggacttg      540

ggggatctga acgagtcgga cttcctcaac aatgcgcact ttcctgagca cctggaccac      600

tttacggaga acatggagga cttctccaat gacctgttca gcagcttctt tgatgaccct      660

gtgctggatg agaagagccc tctattggac atggaactgg actcccctac gccaggcatc      720

caggcggagc acagctactc cctgagcggc gactcagcgc cccagagccc ccttgtgccc      780

atcaagatgg aggacaccac ccaagatgca gagcatggag catgggcgct gggacacaaa      840

ctgtgctcca tcatggtgaa gcaggagcag agcccggagc tgcccgtgga ccctctggct      900

gccccctcgg ccatggctgc cgcggccgcc atggccacca ccccgctgct gggcctcagc      960

cccttgtcca ggctgcccat cccccaccag gccccgggag agatgactca gctgccagtg     1020

atcaaagcag agcctctgga ggtgaaccag ttcctcaaag tgacaccgga ggacctggtg     1080

cagatgcctc cgacgccccc cagcagccat ggcagtgaca gcgacggctc ccagagtccc     1140

cgctctctgc ccccctccag ccctgtcagg cccatggcgc gctcctccac ggccatctcc     1200

acctccccac tcctcactgc ccctcacaaa ttacagggga catcagggcc actgctcctg     1260

acagaggagg agaagcggac cctgattgct gagggctacc ccatccccac aaaactcccc     1320

ctcaccaaag ccgaggagaa ggccttgaag agagtccgga ggaaaatcaa gaacaagatc     1380

tcagcccagg agagccgtcg taagaagaag gagtatgtgg agtgtctaga aaagaaggtg     1440

gagacattta catctgagaa caatgaactg tggaagaagg tggagaccct ggagaatgcc     1500

aacaggaccc tgctccagca gctgcagaaa ctccagactc tggtcaccaa caagatctcc     1560

agaccttaca agatggccgc cacccagact gggacctgcc tcatggtggc agccttgtgc     1620

tttgttctgg tgctgggctc cctcgtgccc tgccttcccg agttctcctc cggctcccag     1680

actgtgaagg aagaccccct ggccgcagac ggcgtctaca cggccagcca gatgccctcc     1740

cgaagcctcc tattctacga tgacggggca ggcttatggg aagatggccg cagcaccctg     1800

ctgcccatgg agcccccaga tggctgggaa atcaaccccg gggggccggc agagcagcgg     1860

ccccgggacc acctgcagca tgatcacctg gacagcaccc acgagaccac caagtacctg     1920

agtgaggcct ggcctaaaga cggtggaaac ggcaccagcc ccgacttctc ccactccaag     1980

gagtggttcc acgacaggga tctgggcccc aacaccacca tcaaactctc ctaggccatg     2040

ccaagaccca ggacatagga cggacccctg gtacccagaa gaggagttct tgctcactaa     2100

cccggatccg cctcgtgccc ctgcctcctg gagcttccca ttccaggaga aaaggctcca     2160

cttcccagcc cttccttgcc cctgacattt ggactcttcc cttgggccga ccactctgtt     2220

ctcattctcc ttcccaccaa catccatccg tccttctcag acaaaccact cactgggtac     2280

cccacctcct ctctcatatg cccaacacga ccactgcctc cctgccccca cacctgcacc     2340

caaacagaca catcaacgca ccccactcac agacacccct taccccaccc ccactgtaca     2400

gagaccaaga acagaaattg tttgtaaata atgaacctta ttttttatta ttgccaatcc     2460

cctaagatat tgtattttac aaatctccct cttcccttcg cccctccctt gttttatatt     2520

ttatgaagtt agtgcgggct ttgctgctcc ctggcccagg aaagagggac tacctgaccc     2580

tcacctggca cccccctgct gctgcccaag ccgctgggcc tttttaattg ccaaactgct     2640

ctcttcatca gctcagcaca tgctttaaga aagcaaaacc aaaaaaaaaa aaaaaaagat     2700

gcagcatcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                         2741


<210>  2311
<211>  2360
<212>  DNA
<213>  homo sapiens

<400>  2311
cagacggcca tttgtggcgg cgctggaggc tgcgttcggc aggcgctgcg gagacgcgta       60

gaggagcgcg ccccccggcc gctgccgccc ctggcccgtg ccgtcacccc gcttctccgc      120

gcctcgggcg gtacccagcc agtccccagc gccgcgctac cgcgctgacc ggccctccag      180

acgcctcccg gtacccggga ccccagcccg gccgctcgcc cgcagcccgc cggccgcaca      240

cgtccccgga gccgggccta gggcgggcgg cagcggcggc tcggcgcagt caggctgggc      300

tctgtagcgt ccccatggcc gcggccggct ggcgggacgg ctccggccag gagaagtacc      360

ggctcgtggt ggtcggcggg ggcggcgtgg gcaagtcggc gctcaccatc cagttcatcc      420

agtcctattt tgtaacggat tatgatccaa ccattgaaga ttcttacaca aagcagtgtg      480

tgatagatga cagagcagcc cggctagata ttttggatac agcaggacaa gaagagtttg      540

gagccatgag agaacagtat atgaggactg gcgaaggctt cctgttggtc ttttcagtca      600

cagatagagg cagttttgaa gaaatctata agtttcaaag acagattctc agagtaaagg      660

atcgtgatga gttcccaatg attttaattg gtaataaagc agatctggat catcaaagac      720

aggtaacaca ggaagaagga caacagttag cacggcagct taaggtaaca tacatggagg      780

catcagcaaa gattaggatg aatgtagatc aagctttcca tgaacttgtc cgggttatca      840

ggaaatttca agagcaggaa tgtcctcctt caccagaacc aacacggaaa gaaaaagaca      900

agaaaggctg ccattgtgtc attttctaga atcccttcag ttttagctac caacggccag      960

gaaaagccct catcttctct ttctctcctc agtttacatc ttgttggtac ctttctagcc     1020

ttagacaaat gatcaccatg ttagccttag acgaagaagc tggctagtcc tttctgtgaa     1080

gctaatacaa tggtcatttc cagacaaatt taaaggaaac actaaggctg cttcaaagat     1140

tatctgattc ctttaaaata tatgtctata tacacagaca tgctcttttt ttaagtgctt     1200

acattttaat agagatgaat cagttttgga atctaagctg tttgccaagc tgaagctaca     1260

ggttgtgaaa taatttttaa cttttggaat catactgcct actgttactc taaatagaaa     1320

tatagggttt tttttaatgt gaatttttgc ctatctttaa acatttcaat gtcagccttt     1380

gttaacctta aatacactga attgaatcta caaaagtgaa ccatctcaga cctttactga     1440

tactacaact tttgttttct gatggccaaa ataccaaatg cctgttgtat ttatggatta     1500

aaaactgctt ataaaaccct gtgttactac tcctactctt ggagatgata atattctatg     1560

tggtcaaata tttggactca tttaggactt agatatttca gtgtacttga ttttttaatt     1620

taactctttt tcacagccac gctaagggta aaaaggaata atttccttct gtcttccttt     1680

tcaagtattt ctgggtaagg gattcaaaaa actaaaactg tttttgtttg taatataaaa     1740

tatggaattg atctttccag ggtcagagat gattaatgtt tttgctatat acttttatac     1800

attattttct tatcaaacta gttaacaagt atttttatat gtttgtaagc agatatgctt     1860

tcatagcata ccttgtgtat atgtaaagat aagtatttaa ttctcactgt tcacttttaa     1920

ctgacaaaga aaaacaagtg gaaactacag aaactgtggt agaactttta cttgctggtc     1980

tggtcttggt tgtacccatc tttggccagt cacataacta ctcaagaaac cttcccaata     2040

gagtacaaca ggatgagact ctgaaatcac tttcagtatt ccctgctaga tattgattgt     2100

tatttcaagt attaagtgta agcttttaat ggataattag tataactgtg gatggcatct     2160

gattttgttt ttaattctgt ggattgtgtt taagcaattc aatagtatgt tcctgatttt     2220

gagatgctaa gtggtattgc acagttgtca ctttatcaag tgtgtacaac agtcccatga     2280

agtttataga gcataccctt gtatagcttc aggtgctaga attaaaattg atctgttatc     2340

acaagaaaaa aaaaaaaaaa                                                 2360


<210>  2312
<211>  8082
<212>  DNA
<213>  homo sapiens

<400>  2312
actggcccgc cgaaagcaca tggattacag tctgaggctg taatgggaaa gtcggttcct       60

gggctgctgt ctcatagaca tcagcttgca gggaagctgg gggctctccg aattgccctg      120

ctccggggcc cctcctgctg cgtgactcac aggcacattg cagagagaag ctgccgctcc      180

cagtaagtaa tgaaaagaga catgaagaat tggtatttca aatgaccacc atgttgcaaa      240

agtctgacag caatgcaagc ttcctccgtg ctgccagagc aggcaacctg gacaaagttg      300

tggaatatct gaaggggggc atagacatca atacctgcaa tcagaatgga ctcaacgctc      360

tccatctggc tgccaaggaa ggccacgtgg ggctggtgca ggagctgctg ggaagagggt      420

cctctgtgga ttctgccact aagaagggaa ataccgctct tcacattgca tctttggctg      480

gacaagcaga agttgtcaaa gttcttgtta aggaaggagc caatattaat gcacagtctc      540

agaatggctt tactccttta tacatggctg cccaagagaa tcacattgat gttgtaaaat      600

atttgctgga aaatggagct aatcagagca ctgctacaga ggatggcttt actcctctag      660

ctgtggcact ccagcaagga cacaaccagg cggtggccat cctcttggag aatgacacca      720

aagggaaagt gaggctgcca gctctgcata ttgccgctag gaaagacgac accaaatctg      780

ccgcacttct gcttcagaat gaccacaatg ctgacgtaca atccaagatg atggtgaata      840

ggacaactga gagtggtttt acccctttgc acatagctgc acattacgga aatgtcaacg      900

tggcaactct tcttctaaac cggggagctg ctgtggactt cacagccagg aatggaatca      960

ctcctctgca tgtggcttcc aaaagaggaa atacaaacat ggtgaagctc ttactggatc     1020

gaggcggtca gatcgatgcc aaaactaggg atgggttgac accacttcac tgtgctgcac     1080

gaagtgggca tgaccaagtg gtggaacttc tgttggaacg gggtgccccc ttgctggcaa     1140

ggactaagaa tgggctgtct ccactacaca tggctgccca gggagaccac gtggaatgtg     1200

tgaagcacct gttacagcac aaggcacctg ttgatgatgt caccctagac tacctgacag     1260

ccctccacgt tgctgcgcac tgtggccact accgtgtaac caaactcctt ttagacaaga     1320

gagccaatcc gaacgccaga gccctgaatg gttttactcc actgcacatt gcctgcaaga     1380

aaaaccgcat caaagtcatg gaactgctgg tgaaatatgg ggcttcaatc caagctataa     1440

cagagtctgg cctcacacca atacatgtgg ctgccttcat gggccacttg aacattgtcc     1500

tccttctgct gcagaacgga gcctctccag atgtcactaa cattcgtggt gagacggcac     1560

tacacatggc agcccgagcc gggcaggtgg aagtggtccg atgcctcctg agaaatggtg     1620

cccttgttga tgccagagcc agggaggaac agacaccttt acatattgcc tcccgcctgg     1680

gtaagacaga aattgtccag ctgcttctac aacatatggc tcatccagat gcggccacta     1740

caaatgggta cacaccactg cacatctctg cccgggaggg ccaggtggat gtggcatcag     1800

tcctattgga agcaggagca gcccactcct tagctaccaa gaagggtttt actcccctgc     1860

atgtagcagc caagtatgga agcctggatg tggcaaaact tctcttgcaa cgccgtgctg     1920

ccgcagattc tgcagggaag aacggcctta ccccgctcca tgttgctgct cattatgaca     1980

accagaaggt ggcgctgctg ttactggaga agggtgcttc ccctcatgcc actgccaaga     2040

atggctatac tccgttacat attgctgcca agaagaatca aatgcagata gcttccacac     2100

tcctgaacta tggagcagag acaaacattg tgacaaagca aggagtaact ccactccatc     2160

tggcctcgca ggaggggcac acagatatgg ttaccttgct tctggataag ggagccaata     2220

tccacatgtc aactaagagt ggactcacat ccttacacct tgcagcccag gaagataaag     2280

tgaatgttgc tgatattctc accaagcatg gagctgatca ggatgctcat acaaagcttg     2340

gttacacacc tttaattgtg gcctgtcact atggaaatgt gaaaatggtc aactttcttc     2400

tgaagcaggg agcaaatgtt aacgcaaaaa ccaagaacgg ctacacgcct ttgcaccagg     2460

ccgctcagca gggtcacacg cacatcatca acgtcctgct ccagcatggg gccaagccca     2520

acgccaccac tgcgaatggc aacactgcct tggcgattgc taagcgtctg ggctacatct     2580

ccgtggtcga caccctgaag gttgtgactg aggaggtcac caccaccacc acaactatta     2640

cagaaaaaca caaactaaat gtacctgaga cgatgactga ggttcttgat gtttctgatg     2700

aagagggtga tgacacaatg actggtgatg ggggagaata ccttaggcct gaggacctaa     2760

aagaactggg tgatgactca ctacccagca gtcagttcct ggatggtatg aattacctgc     2820

gatacagctt ggagggagga cgatctgaca gccttcgatc cttcagttcc gacaggtctc     2880

acactctgag ccatgcctcc tacctgaggg acagtgccgt gatggatgac tcagttgtga     2940

ttcccagtca ccaggtgtca actctagcca aggaggcaga aaggaattct tatcgcctaa     3000

gctggggcac tgagaactta gacaacgtgg ctctttcttc tagtcctatt cattcaggcc     3060

gcgcctctcc atgtcttgaa cgtgacaaca gcagtttcct ggttagtttt atggtggatg     3120

cccgaggtgg tgctatgcga ggatgcagac acaatgggct ccgaatcatt attccacctc     3180

ggaaatgtac tgctccaacg cgagtcacct gccgactggt caagcgccac agactggcaa     3240

caatgcctcc aatggtggaa ggagaaggcc tggccagtcg cctgatcgaa gttggacctt     3300

ctggtgctca gttccttggt aaacttcacc tgccaacggc tcctccccca cttaatgagg     3360

gagaaagttt ggtcagccgc attcttcagc tggggcctcc tggaaccaaa ttccttgggc     3420

ctgtgatcgt ggagatccct cactttgcgg cccttcgagg aaaggaaagg gaactggtgg     3480

tcctgcgcag tgagaatggg gacagctgga aagagcattt ctgtgactac actgaagatg     3540

aattgaatga aattcttaac ggcatggatg aagtactgga tagcccagaa gacctagaaa     3600

agaaacgaat ctgccgcatc atcacccgag acttcccaca gtactttgca gtggtgtctc     3660

gtatcaaaca ggacagcaat ctgattggcc cagaaggagg tgtactgagc agcacagtgg     3720

tgccccaggt gcaggccgtc ttcccagagg gggcactcac caagcggatc cgcgtaggcc     3780

tgcaggctca acctatgcac agtgagctgg ttaagaagat cctaggcaac aaagctacct     3840

tcagccctat agtcactttg gaacctagaa gaagaaaatt ccacaaacca attaccatga     3900

ccattcctgt ccccaaagct tcaagtgatg tcatgttgaa tggttttggg ggagatgcac     3960

caaccttaag attactatgc agcataacag gtggaaccac ccctgcccag tgggaagata     4020

ttacaggaac tacgccatta acatttgtca atgaatgtgt ttcctttaca acaaacgtgt     4080

ctgccaggtt ctggctgata gattgtcgac agatccagga atccgttact tttgcatcac     4140

aagtatacag agaaattatc tgcgtacctt atatggccaa atttgtagtg tttgccaaat     4200

cacatgaccc cattgaagcc aggttgaggt gtttctgcat gactgatgat aaagtggata     4260

agacccttga acaacaagaa aattttgctg aggtggccag aagcagggat gtggaggtgt     4320

tagaaggaaa acccatctac gttgattgtt tcggcaactt ggtaccatta actaaaagtg     4380

gccagcatca tatattcagt ttttttgcct tcaaagaaaa tagacttcct ctatttgtca     4440

aggtacgcga tacgactcag gaaccttgcg gacgactatc atttatgaag gagccaaaat     4500

ccacgagagg cctggtgcat caagctattt gcaacttaaa catcactttg ccgatttata     4560

caaaggaatc agagtcagat caagaacagg aggaagagat cgatatgaca tcagaaaaaa     4620

atccacagga tgagcaggaa cggatcgagg aaaggctggc ttatattgct gatcaccttg     4680

gcttcagctg gacagaatta gcaagagaac tggatttcac tgaggagcaa attcatcaaa     4740

ttcgaattga aaatcccaac tctcttcaag accagagtca tgcactgttg aagtactggc     4800

tagagaggga tgggaaacat gctacagata ccaacctcgt tgaatgtctc accaagatca     4860

accgaatgga tattgttcat ctcatggaga ccaacacaga acctctccag gagcgcatca     4920

gtcatagtta tgcagaaatt gaacagacca ttacactgga tcatagtgaa gggttctcgg     4980

tacttcaaga ggagttatgc actgcacagc acaagcagaa agaggagcaa gctgtttcta     5040

aagaaagtga gacctgcgat caccctccta tcgtctcaga ggaagacatt tctgttggtt     5100

attccacttt tcaggatggc gtccccaaaa ctgaggggga cagctcagca acagcactct     5160

ttccccaaac tcacaaggag caagttcaac aggatttctc agggaaaatg caagacctgc     5220

ctgaagagtc atctctggaa tatcagcagg aatattttgt gacaactcca ggaacagaaa     5280

catcagagac tcagaaggct atgatagtac ccagctctcc cagcaagaca cctgaggaag     5340

ttagcacccc tgcagaggag gagaagctgt acctccagac cccaacatcc agcgagcggg     5400

gaggctctcc catcatacaa gaacccgaag agccctcaga gcacagagag gagagctctc     5460

cgcggaaaac cagcctcgta atagtggagt ctgccgataa ccagcctgag acctgtgaaa     5520

gactcgatga agatgcagct tttgaaaagg gagacgatat gcctgaaata cccccagaaa     5580

cagtcacaga agaagaatac attgatgagc atggacacac cgtggtaaag aaggttacta     5640

ggaaaatcat taggcggtat gtatcctctg aaggcacaga gaaagaagag attatggtgc     5700

agggaatgcc acaggaacct gtcaacatcg aggaagggga tggctattcc aaagttataa     5760

agcgtgttgt attgaagagt gacaccgagc agtcagagga caacaatgag taaagccatc     5820

acacagaaga gggctgtggt gaaggaccag catggaaaac gcattgactt ggagcacctg     5880

gaggatgtac cagaagcact agaccaggac gacctccagc gcgatctcca gcagctcctt     5940

cggcatttct gcaaggagga cttgaagcaa gaggccaagt gaggggctgc ccagttctca     6000

caccagaaac cacacattca ctcaatatgc agcttcctgt ttcagtaggg gagtgaccta     6060

actggcctaa ttaatgggat accccgacat ttccactgtt agcaaatata cggcattttg     6120

ctttagtttt cccccatcct ctttaactat aaagctaatt tgtgaccaaa gatggcatcc     6180

ttcatactgg atgctgtatc caatactttg ttgtgtctgt gctaacctgg gaactggcca     6240

cctccattgt tctttgcttc tgcacaagat ccatgaaaat ccattgatca gaagaacttc     6300

acctgcagac ctcttcaagt gacactatgt aggaatcctt ccaaggaata tctatgtaca     6360

atgtatatag ctgaaatgct cagatgaaca acatattaaa attaaaacca ctgcctattg     6420

taactacact gggcatcaga ataaaaggcc tctagaaatt gctgaacaat ggttaattaa     6480

gatattgcta acacaatcga gtgataatac agttttactg caaaagaagc acttcaaacc     6540

tattatgtcc ttagaacttc cagagtagcc actgctccca gttaaaggtg ggtcagtagc     6600

cttgcagaac tgtcctgaga agttattgct ggtgctggcc agccatggct taggactcca     6660

acagccactc tgagggaggg gagaagggag cagaggccac gcagaatgaa ccgatggggt     6720

attcagttgc tggcagctac attgtgtggc attctagcat cttcaggtct ttagatcttg     6780

gacaagttgg cagggtattt taaaagctat aactactgta gttttccagt tttcattgct     6840

gctttagcaa accacgctgt cttacagtgg tactttcttc tggccactgc actgtagata     6900

attcattgga aacaagattt acccactaca taaaaggtta aactccttca gtatgttgga     6960

gtggtttctt tttttttttc tttctttctt ttttttcttc aggtttatat cttctctaat     7020

acctgcatgt ggcgtttaaa aatcaagacc acggtcaaac ccctcttcta atcacattaa     7080

ttgtttccat tctttttacc ctgagtgagc acttttcact ttccagctag gtctgttttt     7140

cagcttgcag acaagattga gaaatccttg aaaatttggt tttggttaaa atttttggtt     7200

tatttatttg aaatccacac tcccttggaa actcttaagt gcatttgtgc acttctgttt     7260

gtttgtctca aagaagggac tgtaacaatc tgagtaattt ccatgtcctc ttccttattc     7320

ctctagtggt tgaagctgtg tagcatttta acatatatat attcacaaat atattcatat     7380

aaacagtata cattttgaat cagtcatttg ttaaagaaaa gtatattcaa tgaagatgaa     7440

atttaaataa aaaaggacag agtctatcct ccagggattg aacattttcc aattatctgg     7500

tcttttcctg ttgtgcaaaa atgactcatt gctccgaatg tcaaaaacaa atgcgacaaa     7560

caatggcact tcatcattta aagtaatgtt gccaagagaa aaaatttcct gggagggagg     7620

tttcccacaa gccaaatctc ctaagcctca aatgctagca ctttttggca gttggatagg     7680

aaatgagaca ttctttggca gccaaaataa gagaggccga tggtgaaact ttttgagaca     7740

ccctatggcc ttcttgtcaa aaccttcact ggagctcaag aaaagcattt ctgttgtgtt     7800

atttgcagtg cagatgatgt ctgtgtaaca acataatggt tattcacctt tttttgattt     7860

tgatttttgc tgtgttatca aaaacttgaa tactgtgaga agaagtgaat tttcagttga     7920

cgaatcagca tcttgttccc atggtgataa cactaattga atatatctat gagggcatgt     7980

attagttaat ggaaaaaaaa atacaacact aacaatacat agctgcaatg tgtacaatgg     8040

ctgatttaat taaataaaat gtacaagtgt taaatgtggc aa                        8082


<210>  2313
<211>  4869
<212>  DNA
<213>  homo sapiens

<400>  2313
gtcatgctct attgcgcata tctcggggcg ggggaggaac ggagattgac aaggaggcag       60

aggcctgagc gaggcggaaa atcctcaccc cggcccgcgg gtagacccaa acttctagcg      120

cgtcacttcc gctgggggcg gagcggggcg gggctgagtg ggtggcgacc tagctgctgc      180

gccagtgttt gtgttggaag ctcagctgat gcaggccggt tggagtggac gtcattgccg      240

ggaacgagcg agtcgccgct gcagccctag tgactgcggc ctgcatcccg attgtcttct      300

cctccaaggt ctacatgatt acctgaagtt taataatttt gcctttctag agtgttatac      360

agctggaatc atactgctat ggtccgaatg tttgtgcctc tcaaaattca tgtggaaatc      420

ataaccgcta aagtgatggt attaagaggt aagaccatga attatggcat ttcttaaatg      480

aagcgttcaa gaagtgagag aatgtcatag aaaataaatg atttttaagt tatgtctatt      540

aatctgactg tagatatata tatttacctc cttagtaatg caagaagtgt ttgtgggaag      600

cagagaagca agcaactgta tttcttgttc tcacctaagc attactggag gataagccac      660

atcagtctac aaagaggttt tcatacaaac ataataagat gtaaatggac caaaagtgaa      720

gcacattctt gcagtaagca ctgttactct ccaagcaacc atggtttaca tattgggatt      780

ttgaaactta gcacttctgc tcccaaggga cttacaaaag tgaacatttg tatgtcccgt      840

attaaaagta ctttgaactc tgtttcaaag gctgtttttg gcaatcaaaa tgaaatgatt      900

tcacgtttag ctcaatttaa gccaagttcc caaattttaa gaaaagtatc ggatagtggc      960

tggttaaaac agaaaaacat caaacaagcc atcaaatctc tgaaaaaata tagtgacaaa     1020

tcagcagaaa agagtccttt tccagaagag aaaagtcaca ttatagacaa agaagaagat     1080

ataggtaaac gcagtctttt tcattacaca agttctataa ccacaaaatt tggagactca     1140

ttctactttt tatcaaatca tattaattca tatttcaaac gtaaggaaaa aatgtctcaa     1200

caaaaggaaa atgaacattt ccgggacaaa tcagaacttg aagataaaaa ggtagaagag     1260

gggaaattaa gatctccaga tcctggcatc ctggcttata agccaggctc agaatctgta     1320

catacggtgg acaagcctac aagtccttct gcgatacctg atgttcttca agtttcaact     1380

aaacaaagta ttgctaactt tctttctcgt cccacggaag gtgtacaagc tttagtaggt     1440

ggttatattg gtggacttgt ccccaaatta aagtatgatt caaagagtca gtcagaagaa     1500

caggaagagc ctgctaaaac tgatcaggct gtcagcaaag acagaaatgc agaggagaaa     1560

aagcgtttat ctcttcagcg agaaaagatt atcgcaaggg tgagtattga taacaggacc     1620

cgggcattag ttcaggcatt aagaagaaca actgacccaa agctctgcat tactagggtt     1680

gaagaactga cttttcatct tctagaattt cctgaaggaa aaggagtggc tgtcaaggaa     1740

agaattattc catatttatt acgactgaga caaattaagg atgaaactct tcaggctgca     1800

gttagagaaa ttttggccct aattggctat gtggatccag tgaaagggag aggaatccga     1860

attctctcaa ttgatggtgg aggaacaagg ggcgtggttg ctctccagac cctacgaaaa     1920

ttagttgaac ttactcagaa gccagttcat cagctctttg attacatttg tggtgtaagc     1980

acaggtgcca tattagcttt catgttgggg ttgtttcata tgcccttgga tgaatgtgag     2040

gaactttatc gaaaattagg atcagatgta ttttcacaaa atgtcattgt tggaacagta     2100

aaaatgagtt ggagccatgc attttatgac agtcaaacat gggaaaacat tcttaaggat     2160

aggatgggat ctgcactgat gattgaaaca gcaagaaacc ccacatgtcc taaggtagct     2220

gctgtaagta ccatagtaaa tagagggata acacccaaag cttttgtgtt cagaaactat     2280

ggtcattttc ctggaatcaa ctctcattat ttgggaggct gtcagtataa aatgtggcag     2340

gccattagag cctcatctgc tgctccaggc tactttgcag aatatgcatt gggaaatgat     2400

cttcatcaag atggaggttt gcttctgaat aacccttcgg cattagctat gcatgagtgt     2460

aaatgtcttt ggccagatgt gccgttagag tgcatagtat ccctgggcac tggacgttat     2520

gagagtgatg tgagaaacac ggtaacatac acaagcttga aaactaaact ttctaatgtt     2580

atcaacagtg ctacagatac agaagaagtc catataatgc ttgatggcct gttacctcct     2640

gacacctatt ttagattcaa tcctgtaatg tgtgaaaaca tacctctaga tgaaagtcga     2700

aatgaaaagc tggatcagct gcagttggaa gggttgaaat acatagaaag aaatgaacaa     2760

aaaatgaaaa aagttgcaaa aatattaagt caagaaaaaa caactctgca gaaaattaat     2820

gattggataa aattaaaaac tgatatgtat gaaggacttc cattcttttc aaaattgtga     2880

tgagtatatg cttatgttct cataaatgaa ggtctgttta gaagatcaac cacattcaat     2940

aaggaattgt ggggttcgac atgagttaac tttgaaatac gtatgaattc tggagaatcc     3000

tgaaaaagac ggtgcttcaa ccagcttgca tagcacagag aatattcttg gttacagaat     3060

tcatatggga actaggcttt taagatgtta ataattagct aagctttagt aacccttact     3120

gtgctagtag attttagtag atattggtgt tatattgttt gatgtttgaa aatatattaa     3180

tatatgtgcc gaacaagaaa ccgaaagcta tattgtactg tgtattttta ctttagtcct     3240

cataatcatg ttgaatttat gtgatcattg attttatttc atatggaaaa gctaatttct     3300

tcttaaattt acattaccta atattctcac tagctatgtt ctccaatcca cactgccttt     3360

tattgtaata tcatctaaat agatgcagaa aaatggaatt ttctctatta aagtatttta     3420

catttgacat aaaaaagaac cagatacagt tttctattca gatatgttta ttttaacatt     3480

gtttggttaa aaaaggtgaa gttccagtca accacttttt acccctgaaa tttcaagata     3540

atgctatatt aacttttcca gatctaacac tagcttattc ttccctgtta taaaatggtt     3600

tgaacttact gaggagatat tcctatcatt aacaaaaata aactatttaa ataatctgtt     3660

gttaaaaggc taatgtcatt ttaaaattaa tttttgttca taatgtagct cccctttagc     3720

ctttgaatac acctggcagc agtatgctta aaaataagaa gttagttgcc tggcgcagta     3780

gctcacacct gtaatcccag cactttggga ggccgaggca ggcagatcac ctgacgtcag     3840

gagtccaaga ccagcctggc caacacggtg aaacctcgtc tctaataaaa atacaaacat     3900

tagcccggca tggtggtgca cacctatagt cccagctact cgggaggcta aggcaggaga     3960

atggcttgaa cctgagagac ggaggttgca gtgagccaaa tagcgccagt gcactccagc     4020

ctaggcgaca cagcgagact ccatctcaaa aaaaaaaaaa aaaaaaagaa gaagttaggc     4080

ttgttttacc ttattaactc ctttgaactg tctggatttc atggaagttg gtaagatgca     4140

cttacatgga acattgttca tgccaaacaa actcatcttt attgtatcta tttgtcacat     4200

aaatccttac atggaatgtt ttgatttctt aagaaaaatg aaacaaaggt tagcgcccct     4260

tgttttagac atacaaacta aagctagacc ctgttgccca gatagtcata ttgcttcttt     4320

gcaatatcaa ttcacagagg ctgtgagatg tggttcaaag agtggagtcg agagtctgga     4380

tgctaatcct gcctttgctg caagaaccct tctgtttgtt accttgagga aggcaaatgt     4440

ctgtaggctt tgcatatctc atttgtaaaa tgaggaaagg tagctgtaaa attttctaac     4500

atccgaatta tataaacttt agacatagta taaaatagga aactaccaat gatttctaaa     4560

gataatatag ttctttcaga ccacaaataa tacataataa catgcaacta agaacaactt     4620

gtaaatgcaa gaaaaaaaca aataattgga aatcagaata tttctgggaa ttcttcgtaa     4680

taaagcaaat ttcaagcaca ataaagtaat atttatgcat atttacatat ttgcacctca     4740

tcataaggtc actctagtcc taaactgatg tagttcatct gttttacagc tgaagttaag     4800

tatgtccctt atttgtgctt ggcttatttc tttcttaaat aatacattac acaagtgaaa     4860

aaaaaaaaa                                                             4869


<210>  2314
<211>  4089
<212>  DNA
<213>  homo sapiens

<400>  2314
acggcccggc gacgggggag ttcccgcgag tggcctcgcg cccagaccgt gcggggggct       60

gttcgggtgg aggcggggga gccgccggga caccaaaata ggagctgctt gtggggtgga      120

gcggcactag ctggcggctt ccgagcgcct cttccaaaga tggtcagagg ggccggaggc      180

gtccccgctc ccgctcgcta ctagcccgcg ggccagcgcc gcgtcccgag ccccggcggg      240

agccatggct ctaaaaggac aagaagatta tatttatctt ttcaaggatt caacacatcc      300

agtggatttt ctggatgcat tcagaacatt ttacttggat ggattattta ctgatattac      360

tcttcagtgt ccttcaggca taattttcca ttgtcaccga gccgttttag ctgcttgcag      420

caattatttt aaggcaatgt tcacagctga catgaaagaa aaatttaaaa ataaaataaa      480

actctctggc atccaccatg atattctgga aggccttgta aattatgcat acacttccca      540

aattgaaata actaaaagaa atgttcaaag cctgcttgag gcagcggatc tgctacagtt      600

cctttcagta aagaaggctt gtgagcggtt tttggtaagg cacttggata ttgataattg      660

tattggaatg cactcctttg cagaatttca tgtgtgtcca gaactagaga aggaatctcg      720

aagaattcta tgttcaaagt ttaaggaagt gtggcaacaa gaagaatttc tggaaatcag      780

ccttgaaaag tttctcttta tcttgtccag aaagaatctc agtgtttgga aagaagaagc      840

tatcatagag ccagttatta agtggactgc tcatgatgta gaaaatcgaa ttgaatgcct      900

ctataatcta ctgagctata tcaacattga tatagatcca gtgtacttaa aaacagcctt      960

aggccttcaa agaagctgcc tgctcaccga aaataagatc cgctccctaa tatacaatgc     1020

cttgaatccc atgcataaag agatttccca gaggtccaca gccacaatgt atataattgg     1080

aggctattac tggcatcctt tatcagaggt tcacatatgg gatcctttga caaatgtttg     1140

gattcaggga gcagaaatac cagattatac cagggagagc tatggtgtta catgtttagg     1200

acccaacatt tatgtaactg ggggctacag gacggataac atagaagctc ttgacacagt     1260

gtggatctat aacagtgaaa gtgatgaatg gacagaaggt ttgccaatgc tcaatgccag     1320

gtattaccac tgtgcagtca ccttgggtgg ctgtgtctat gctttaggtg gttacagaaa     1380

aggggctcca gcagaagagg ctgagttcta tgatccttta aaagagaaat ggattcctat     1440

tgcaaacatg attaaaggtg tgggaaatgc tactgcctgt gtcttacatg atgttatcta     1500

cgtcattggt ggccactgtg gctacagagg aagctgcacc tatgacaaag ttcagagcta     1560

caattccgat atcaacgaat ggagcctcat cacctccagt ccacatccag aatatggatt     1620

gtgctcagtt ccgtttgaaa ataagctcta tctagtcggc ggacaaacta caatcacaga     1680

atgctatgac cctgaacaaa atgaatggag agagatagct cccatgatgg aaaggaggat     1740

ggagtgcggt gccgtcatca tgaatggatg tatttatgtc actggaggat actcctactc     1800

aaagggaacg tatcttcaga gcattgagaa atatgatcca gatcttaata agtgggaaat     1860

agtgggtaat cttcccagtg ccatgcggtc tcatgggtgt gtttgtgtgt ataatgtcta     1920

attgaatctg cagaaatgac caagcaatca cttttttgga gtatagtttt ataaaaaaag     1980

aatgcagggt ttgaagttcc ttacctgata attgtgtctg gcacatgata ggggatcagt     2040

aaattgtaat tcctaaccct actgtactcc caaacatggt gattcatggt caagaaaaat     2100

cttatatata tatatatata cacacacaca tatatgtgtt catatatatg tatacatata     2160

tatgtgtata tatacgtatg tatacatata tgtgtatata tacgtatgta tgtatacata     2220

tgtgtatata tagtatgtat gtatacatgt atgtgtatat atacgtatgt atgtatacat     2280

atatgtgtat acatatatat gtgtgtatat atatacacat atatacgtat atatgtgtat     2340

atatatacac agttgaatca gtgggattaa tacctataat ctctggtttt caaaggtaat     2400

atagaatatt tgacacttgg taaaaggtga actacctttg tagtgaatct tttcctcttg     2460

gtagcatcaa cactggggat aaatcagaac cattctgtgg aatgaaatgt ttctcaagag     2520

cctataatat agtagatagt gcatattaag atgtctggct gggcatggtg gctcatgcct     2580

gtaatcccag cactttggga ggctgaggcg ggaggatcac ttgagcctag aagttggaga     2640

ctaacctggc gagaccctgt ctcaaaaaaa aaaaaaaatc aatttagcta gcaggaattt     2700

gacatttaaa gagggaatct tctctacctc tacaaaatca acccttaaca cttttttcac     2760

cttcagaatt atttagaatg tggatttact ttgtctagtt ttttccttta tagtgtaatt     2820

tattgttact ctctatttac tgactaccag agatatacaa aatactgtgc aaaagattgt     2880

tactgttcaa agagcttaca aactaaattt aaaagaatag caagtctgaa aaatagaaga     2940

tagtcaaata tttgtttatg ctaagaactg tttttaattt tcagctttga tgtaaattgc     3000

tagcttagtt gtctttagtt caagcatgtt aggaaatcct ctttattctt aaatatagat     3060

acatgtctgc atatatgatt gaattttaga gccagaaagc atgtagagca gttgtgatta     3120

gtagaaaata cactgacaag aagatatttg catttatttc ccaaagctgc cagtaactag     3180

attttgtgac ttaagtcatt taacctctcc ttgattagag cttcctgagc catgcacact     3240

ggcactgcaa atcacagaca ggcctagata cagatcccct caccccttgc tacatccaaa     3300

ggtggcctgg gtggctggag cctctgggcc agaaccacct ttgtccattt tcctcagtgt     3360

gcctacagca tcgctttcca tgtgtgccat aacttgggaa tagttgggat gtgttgctta     3420

actcctttac accattagtt atctgtgaga ccatctattc cacactcttc attttttaaa     3480

aagagacaat aattattttt aactcactga agtttaaaac tacctagcat ttctgattaa     3540

aaaaaattta gaaggaaaat tttaatgcat ttatttcaga tggcgtttta aatagataca     3600

accctttgga aacacaatat ggtactacat agcaagggct gtaaaaatga ccatatcctt     3660

tgccccataa attctacttc tatactttta accttaaaaa taattcagaa aaaagataaa     3720

tgcatgaaga catttatgtc tgcattcttt ataataacaa aaattgggga aaaaaactcc     3780

atgtcaagaa agtgggataa gaaaaatagt gaagtattat actgccatta aaataattat     3840

ttggaagact gtagaaacgt ggacatgttt gatatggtaa gtaaaatgag cacaatacaa     3900

aatagtatgc atactatgat tgtgactttg taaaatcttt atgcatgtgg aaggtaatct     3960

gcaaaacaaa ttcattgtgt tagtgtagcg ggatatggaa tgactttatt tatttaaatc     4020

ttttctttaa tattactttg tattttcaat aaaaataaat cactgtacat agtaaaaaaa     4080

aaaaaaaaa                                                             4089


<210>  2315
<211>  3186
<212>  DNA
<213>  homo sapiens

<400>  2315
caggtgatta tcctaattaa tgtctatcta attaaattac tgtcagcagc taaccaatgg       60

caggagccgt ttcatcggct gcacaagcag caagatcaaa agtgagcctt ttctgattgc      120

tgcatagtgt caattggcca atctcttctc ccagggaaaa aaaaaagtaa atcaaacctt      180

tgagaagcat ttgctggttg aagtgctttc tgtctagtga gggggtctgt ggatttctag      240

tttatgataa ataggacttt aaaaaccagg gacgggaggg cgagtgttca ggttctagag      300

ctatgcagct ggagcactgc ctttctcctt ctatcatgct ctccaagaaa tttctcaatg      360

tgagcagcag ctacccacat tcaggcggat ccgagcttgt cttgcacgat catcccatta      420

tctcgaccac tgacaacctg gagagaagtt cacctttgaa aaaaattacc agggggatga      480

cgaatcagtc agatacagac aattttcctg actccaagga ctcaccaggg gacgtccaga      540

gaagtaaact ctctcctgtc ttggacgggg tctctgagct tcgtcacagt ttcgatggct      600

ctgctgcaga tcgctacctc ctctctcagt ccagccagcc acagtctgcg gccactgctc      660

ccagtgccat gttcccgtac cccggccagc acggaccggc gcaccccgcc ttctccatcg      720

gcagccctag ccgctacatg gcccaccacc cggtcatcac caacggagcc tacaacagcc      780

tcctgtccaa ctcctcgccg cagggatacc ccacggccgg ctacccctac ccacagcagt      840

acggccactc ctaccaagga gctccgttct accagttctc ctccacccag ccggggctgg      900

tgcccggcaa agcacaggtg tacctgtgca acaggcccct ttggctgaaa tttcaccggc      960

accaaacgga gatgatcatc accaaacagg gaaggcgcat gtttcctttt ttaagtttta     1020

acatttctgg tctcgatccc acggctcatt acaatatttt tgtggatgtg attttggcgg     1080

atcccaatca ctggaggttt caaggaggca aatgggttcc ttgcggcaaa gcggacacca     1140

atgtgcaagg aaatcgggtc tatatgcatc cggattcccc caacactggg gctcactgga     1200

tgcgccaaga aatctctttt ggaaaattaa aacttacgaa caacaaagga gcttcaaata     1260

acaatgggca gatggtggtt ttacagtcct tgcacaagta ccagccccgc ctgcatgtgg     1320

tggaagtgaa cgaggacggc acggaggaca ctagccagcc cggccgcgtg cagacgttca     1380

ctttccctga gactcagttc atcgccgtca ccgcctacca gaacacggat attacacaac     1440

tgaaaataga tcacaaccct tttgcaaaag gatttcggga taattatgac acgatctaca     1500

ccggctgtga catggaccgc ctgaccccct cgcccaacga ctcgccgcgc tcgcagatcg     1560

tgcccggggc ccgctacgcc atggccggct ctttcctgca ggaccagttc gtgagcaact     1620

acgccaaggc ccgcttccac ccgggcgcgg gcgcgggccc cgggccgggt acggaccgca     1680

gcgtgccgca caccaacggg ctgctgtcgc cgcagcaggc cgaggacccg ggcgcgccct     1740

cgccgcaacg ctggtttgtg acgccggcca acaaccggct ggacttcgcg gcctcggcct     1800

atgacacggc cacggacttc gcgggcaacg cggccacgct gctctcttac gcggcggcgg     1860

gcgtgaaggc gctgccgctg caggctgcag gctgcactgg ccgcccgctc ggctactacg     1920

ccgacccgtc gggctggggc gcccgcagtc ccccgcagta ctgcggcacc aagtcgggct     1980

cggtgctgcc ctgctggccc aacagcgccg cggccgccgc gcgcatggcc ggcgccaatc     2040

cctacctggg cgaggaggcc gagggcctgg ccgccgagcg ctcgccgctg ccgcccggcg     2100

ccgccgagga cgccaagccc aaggacctgt ccgattccag ctggatcgag acgccctcct     2160

cgatcaagtc catcgactcc agcgactcgg ggatttacga gcaggccaag cggaggcgga     2220

tctcgccggc cgacacgccc gtgtccgaga gttcgtcccc gctcaagagc gaggtgctgg     2280

cccagcggga ctgcgagaag aactgcgcca aggacattag cggctactat ggcttctact     2340

cgcacagcta ggccgcccct gcccgcccgg ccccgccgcg gcccggaccc ccagccagcc     2400

cctcacagct cttccccagc tccgcctccc cacactcctc cttgcgcacc cactcatttt     2460

atttgaccct cgatggccgt ctgcagcgaa taagtgcagg tctccgagcg tgattttaac     2520

cttttttgca cagcagtctc tgcaattagc tcaccgacct tcaactttgc tgtaaacctt     2580

ttggttttcc tacttactct tcttctgtgg agttatcctc ctacaattcc cctccccctc     2640

gtctttctct tacctcctac ttctctttct tgtaatgaaa ctcttcacct ttaggagacc     2700

tgggcagtcc tgtcaggcag cagcgattcc gacccgccaa gtctcggcct ccacattaac     2760

cataggatgt tgactctaga acctggaccc acccagcgcg tcctttctta tccccgagtg     2820

gatggatgga tggatggatg gtagggatgt taataatttt agtggaacaa agcctgtgaa     2880

atgattgtac atagtgttaa tttattgtaa cgaatggcta gtttttattc tcgtcaaggc     2940

acaaaaccag ttcatgctta accttttttt cctttccttt ctttgctttt ctttctctcc     3000

tctcatactt tctcttctct ctcttttaat tttcttgtga gataatattc taagaggctc     3060

tagaaacatg aaatactcag tagtgatggg tttcccactt ctcctcaatc cgttgcatga     3120

aataattact atgtgcccta atgcacacaa atagctaagg agaatccacc caaacacctt     3180

taaagg                                                                3186


<210>  2316
<211>  2904
<212>  DNA
<213>  homo sapiens

<400>  2316
gtgggcaaag gtacttaaag ccctgaccgt cgttctccgt cctcctctgg gtaccaactc       60

tattgcgcag ctcgctgccg tgcgtttaac ccaggcgagg aggaggagga gaaaattccc      120

ccagattcgg gcaggcccgc accccacatt ccgtcctgtt ttgagaggag gagggaagag      180

aaataaacgt ggcagcgcat agaaggccag cagggagact gctttccaga cacctccggc      240

ccacacagcc gttcaccccc cgtcttttca gtcctggaaa aggaattcgg tctgtcctta      300

ggatgaagct ctaactgaac tgaagtaagg agaaacagcc ttgaatcttt ggagggtctg      360

tcttcctttt gggctctgtg caactgcagc tacagtggaa aaaagcaaac tgctcttgat      420

cccaggccct gcctaagcct cagcagaact tgtaagccta aactgaagag cctcacccgg      480

acgagcaggc atcccttaac cttaagcaat ccagttccac gccctggatc agtgaataac      540

cccagctgca ccatgagccg cgttcgggat gctggctgtg tagcggcggg gatagtgata      600

ggggctggtg cctggtactg tgtctacaaa tacaccaggg ggagagacca gaccaagaag      660

agaatggcca agcccaaaaa ccgggctgtg gctgggactg gagccagggc tagagctggg      720

ctaagagccg gattcacaat cgaccttggg tcaggattca gtcccccaac cccagtccgt      780

gctgaagcag aggacagggc ccaggatgaa gcctctgctc tggacacagt tggagctgag      840

gcagtggccc cagctgcatc cagcgctgag gctcagagtg gggcaggcag tcaggcccaa      900

gaggcagatg gagccggggt tgggcctaag gccgaatcag tagttggggc tgcaatggct      960

tctgcaatag caccacctcc cggggtgaca gaggcccttg gggctgcaga agcccctgca     1020

atggcagggg ctcccaaagt ggcagaagct cccagagaag cggagacttc cagggcagcg     1080

gtgcctcctg ggacagtggt gcctaccgaa gcggcagcac ccactgaggt gaccgagggt     1140

cctggggtag cagcacctac caaggtagct gaagctcccg gggtggcatc gcctaccgag     1200

gcagctgagg ctcctgtgcc ggcaacgcct actggggctg cagcacctac tggggctgca     1260

gagtctcctg gaacttctgg ttcccctaga acagcggtgg ttcctggaac atcagctgcc     1320

aagaaagcaa cccctggggc tcacactggg gctataccga aagccacatc agcgactgga     1380

gcggtaccca aaggtggagg caagggtgta accaggtccc ggaatggggg caagggcaag     1440

ggcaagaaaa gcaaagttga agtagacgaa ctggggatgg gcttccgtcc tggagatggg     1500

gctgcagcag ctgctgcagc ctctgctaat ggcggacagg ctttcctggc agaggtccct     1560

gattctgagg aaggggagtc cgggtggact gacacagagt cagattcaga ctctgagccc     1620

gagacccagc gcagagggag gggaagaaga cccgttgcca tgcagaagcg cccctttcct     1680

tatgaaattg atgagattct gggtgtccgc gatctcagga aggtccttgc cttgcttcag     1740

aaatctgatg atcctttcat ccaacaggta gctttgctca ctctgagcaa caatgccaat     1800

tattcatgca atcaagagac aatccgcaaa ttgggaggcc tcccaattat tgcaaacatg     1860

atcaacaaaa ctgatccaca cattaaggaa aaagccttaa tggccatgaa taacctgagt     1920

gagaattatg aaaatcaggg ccggcttcag gtgtacatga ataaagtgat ggatgatatc     1980

atggcctcta acctgaactc agcagttcaa gtagttggac taaaatttct aacaaacatg     2040

actattacta atgactacca acacctgctt gtcaattcca ttgcaaactt tttccgtttg     2100

ctatctcagg gaggtggaaa aatcaaggtt gagattttga aaatcctttc gaattttgct     2160

gaaaatccag atatgttgaa gaaacttctc agtacccaag tgccagcatc atttagttcc     2220

ctctataatt cttacgtgga atcagaaatc cttattaatg cccttactct atttgagatt     2280

atctatgaca atctcagagc agaagtgttt aactatagag aattcaataa aggttccctt     2340

ttttacttat gcactacatc tggagtgtgt gttaagaaaa ttagagcctt agcaaatcac     2400

catgacctct tagtgaaagt gaaagttata aaactagtga acaaattctg attggttatg     2460

taccgtcaaa agacttgaag aaatttcatg attttgcagt gtggaagcgt tgaaaattga     2520

aagttactgc ttttccactt gctcatatag taaagggatc ctttcagctg ccagtgttga     2580

ataatgtatc atccagagtg atgttatctg tgacagtcac cagctttaag ctgaaccatt     2640

ttatgaatac caaataaata gacctcttgt actgaaaaca tatttgtgac tttaatcgtg     2700

ctgcttggat agaaatattt ttactggttc ttctgaattg acagtaaacc tgtccattat     2760

gaatggccta ctgttctatt atttgttttg acttgaattt atccaccaaa gacttcattt     2820

gtgtatcatc aataaagttg tatgtttcaa ctgacaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaa                                            2904


<210>  2317
<211>  2853
<212>  DNA
<213>  homo sapiens

<400>  2317
gtgggcaaag gtacttaaag ccctgaccgt cgttctccgt cctcctctgg gtaccaactc       60

tattgcgcag ctcgctgccg tgcgtttaac ccaggcgagg aggaggagga gaaaattccc      120

ccagattcgg gcagacacct ccggcccaca cagccgttca ccccccgtct tttcagtcct      180

ggaaaaggaa ttcgggcttt cattgtctaa cgtcgacagt ctatatttct gctcttcagt      240

ctgtccttag gatgaagctc taactgaact gaagtaagga gaaacagcct tgaatctttg      300

gagggtctgt cttccttttg ggctctgtgc aactgcagct acagtggaaa aaagcaaact      360

gctcttgatc ccaggccctg cctaagcctc agcagaactt gtaagcctaa actgaagagc      420

ctcacccgga cgagcaggca tcccttaacc ttaagcaatc cagttccacg ccctggatca      480

gtgaataacc ccagctgcac catgagccgc gttcgggatg ctggctgtgt agcggcgggg      540

atagtgatag gggctggtgc ctggtactgt gtctacaaat acaccagggg gagagaccag      600

accaagaaga gaatggccaa gcccaaaaac cgggctgtgg ctgggactgg agccagggct      660

agagctgggc taagagccgg attcacaatc gaccttgggt caggattcag tcccccaacc      720

ccagtccgtg ctgaagcaga ggacagggcc caggatgaag cctctgctct ggacacagtt      780

ggagctgagg cagtggcccc agctgcatcc agcgctgagg ctcagagtgg ggcaggcagt      840

caggcccaag aggcagatgg agccggggtt gggcctaagg ccgaatcagt agttggggct      900

gcaatggctt ctgcaatagc accacctccc ggggtgacag aggcccttgg ggctgcagaa      960

gcccctgcaa tggcaggggc tcccaaagtg gcagaagctc ccagagaagc ggagacttcc     1020

agggcagcgg tgcctcctgg gacagtggtg cctaccgaag cggcagcacc cactgaggtg     1080

accgagggtc ctggggtagc agcacctacc aaggtagctg aagctcccgg ggtggcatcg     1140

cctaccgagg cagctgaggc tcctgtgccg gcaacgccta ctggggctgc agcacctact     1200

ggggctgcag agtctcctgg aacttctggt tcccctagaa cagcggtggt tcctggaaca     1260

tcagctgcca agaaagcaac ccctggggct cacactgggg ctataccgaa agccacatca     1320

gcgactggag cggtacccaa aggtggaggc aagggtgtaa ccaggtcccg gaatgggggc     1380

aagggcaagg gcaagaaaag caaagttgaa gtagacgaac tggggatggg cttccgtcct     1440

ggagatgggg ctgcagcagc tgctgcagcc tctgctaatg gcggacaggc tttcctggca     1500

gaggtccctg attctgagga aggggagtcc gggtggactg acacagagtc agattcagac     1560

tctgagcccg agacccagcg cagagggagg ggaagaagac ccgttgccat gcagaagcgc     1620

ccctttcctt atgaaattga tgagattctg ggtgtccgcg atctcaggaa ggtccttgcc     1680

ttgcttcaga aatctgatga tcctttcatc caacaggtag ctttgctcac tctgagcaac     1740

aatgccaatt attcatgcaa tcaagagaca atccgcaaat tgggaggcct cccaattatt     1800

gcaaacatga tcaacaaaac tgatccacac attaaggaaa aagccttaat ggccatgaat     1860

aacctgagtg agaattatga aaatcagggc cggcttcagg tgtacatgaa taaagtgatg     1920

gatgatatca tggcctctaa cctgaactca gcagttcaag tagttggact aaaatttcta     1980

acaaacatga ctattactaa tgactaccaa cacctgcttg tcaattccat tgcaaacttt     2040

ttccgtttgc tatctcaggg aggtggaaaa atcaaggttg agattttgaa aatcctttcg     2100

aattttgctg aaaatccaga tatgttgaag aaacttctca gtacccaagt gccagcatca     2160

tttagttccc tctataattc ttacgtggaa tcagaaatcc ttattaatgc ccttactcta     2220

tttgagatta tctatgacaa tctcagagca gaagtgttta actatagaga attcaataaa     2280

ggttcccttt tttacttatg cactacatct ggagtgtgtg ttaagaaaat tagagcctta     2340

gcaaatcacc atgacctctt agtgaaagtg aaagttataa aactagtgaa caaattctga     2400

ttggttatgt accgtcaaaa gacttgaaga aatttcatga ttttgcagtg tggaagcgtt     2460

gaaaattgaa agttactgct tttccacttg ctcatatagt aaagggatcc tttcagctgc     2520

cagtgttgaa taatgtatca tccagagtga tgttatctgt gacagtcacc agctttaagc     2580

tgaaccattt tatgaatacc aaataaatag acctcttgta ctgaaaacat atttgtgact     2640

ttaatcgtgc tgcttggata gaaatatttt tactggttct tctgaattga cagtaaacct     2700

gtccattatg aatggcctac tgttctatta tttgttttga cttgaattta tccaccaaag     2760

acttcatttg tgtatcatca ataaagttgt atgtttcaac tgacaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa                                  2853


<210>  2318
<211>  2863
<212>  DNA
<213>  homo sapiens

<400>  2318
gcgattggtg ggcggggggc cgggcctggg ccggcgggga gcggattggt cggaaagtag       60

gttagtggtg cgacatttag ggaaggcaga aagtaggtca gggacggagg tgcctgttta      120

cccgcgccgg actcaccgcc gccgccgccg cgggatccga gtgcgggcgc gggcgcgggc      180

gctcccggcg agccacggtg gtgctggcta gagtgtatac gtttggaccc aagcttaact      240

tttccaatgt ggaatcctgg gccttcattg gttccgatgt cataggaatc tacgctagag      300

ggcttcctgt gtgccgggca ctgtggtttt tggaagaagc tgaccgcctg aaaagaaatt      360

ataaaacatg aaaatcgctt tgaggtgacc aagtccagag gcccctaact cctcccaagc      420

tggatctggg gtgtaagaac tgtgacttca gatcatccaa tggcagacca gagaatggac      480

atttcttcaa ccatcagtga tttcatgtcc ccgggcccca ccgacctgct ttccagctct      540

cttggtacca gtggtgtgga ttgcaaccgc aaacggaaag gcagctccac tgactaccaa      600

gaaagcatgg acacagacaa agatgaccct catggaaggt tagaatatac agaacaccaa      660

ggaaggataa aaaatgcaag ggaagctcac agtcagattg aaaagcggcg tcgggataaa      720

atgaacagtt ttatagatga attggcttct ttggtaccaa catgcaacgc aatgtccagg      780

aaattagata aacttactgt gctaaggatg gctgttcagc acatgaaaac attaagaggt      840

gccaccaatc catacacaga agcaaactac aaaccaactt ttctatcaga cgatgaattg      900

aaacacctca ttctcagggc agcagatgga tttttgtttg tcgtaggatg tgaccgaggg      960

aagatactct ttgtctcaga gtctgtcttc aagatcctca actacagcca gaatgatctg     1020

attggtcaga gtttgtttga ctacctgcat cctaaagata ttgccaaagt caaggagcag     1080

ctctcctcct ctgacaccgc accccgggag cggctcatag atgcaaaaac tggacttcca     1140

gttaaaacag atataacccc tgggccatct cgattatgtt ctggagcacg acgttctttc     1200

ttctgtagga tgaagtgtaa caggccttca gtaaaggttg aagacaagga cttcccctct     1260

acctgctcaa agaaaaaaga tcgaaaaagc ttctgcacaa tccacagcac aggctatttg     1320

aaaagctggc cacccacaaa gatggggctg gatgaagaca acgaaccaga caatgagggg     1380

tgtaacctca gctgcctcgt cgcaattgga cgactgcatt ctcatgtagt tccacaacca     1440

gtgaacgggg aaatcagggt gaaatctatg gaatatgttt ctcggcacgc gatagatgga     1500

aagtttgttt ttgtagacca gagggcaaca gctattttgg catatttacc acaagaactt     1560

ctaggcacat cgtgttatga atattttcac caagatgaca taggacatct tgcagaatgt     1620

cataggcaag ttttacagac gagagaaaaa attacaacta attgctataa atttaaaatc     1680

aaagatggtt cttttatcac actacggagt cgatggttca gtttcatgaa cccttggacc     1740

aaggaagtag aatatattgt ctcaactaac actgttgttt tagccaacgt cctggaaggc     1800

ggggacccaa ccttcccaca gctcacagca tccccccaca gcatggacag catgctgccc     1860

tctggagaag gtggcccaaa gaggacccac cccactgttc cagggattcc agggggaacc     1920

cgggctgggg caggaaaaat aggccgaatg attgctgagg aaatcatgga aatccacagg     1980

ataagagggt catcgccttc tagctgtggc tccagcccat tgaacatcac gagtacgcct     2040

ccccctgatg cctcttctcc aggaggcaag aagattttaa atggagggac tccagacatt     2100

ccttccagtg gcctactatc aggccaggct caggagaacc caggttatcc atattctgat     2160

agttcttcta ttcttggtga gaacccccac ataggtatag acatgattga caacgaccaa     2220

ggatcaagta gtcccagtaa tgatgaggca gcaatggctg tcatcatgag cctcttggaa     2280

gcagatgctg gactgggtgg ccctgttgac tttagtgact tgccatggcc gctgtaaaca     2340

ctacatgttg ctttggcaac agctatagta tcaaagtgca ttactggtgg agttttacag     2400

tctgtgaagc ttactggata aggagagaat agcttttatg tactgacttc ataaaagcca     2460

tctcagagcc attgatacaa gtcaatctta ctatatgtaa cttcagacaa agtggaacta     2520

agcctgctcc agtgtttcct catcattgat tattgggcta gctgtggata gcttgcatta     2580

attgtatatt ttggattctg tttgtgttga attttttaat cattgtgcac agaagcatca     2640

ttggtagctt ttatatgcaa atggtcattt cagatgtatg gtgtttttac actacaaaga     2700

agtcccccat gtggatattt cttatactaa ttgtatcata aagccgttta ttcttccttg     2760

taagaatcct ttactataaa tatgggttaa agtataatgt actagacagt taaatatttt     2820

taataaatgt ttcccttgtt ctataaaaaa aaaaaaaaaa aaa                       2863


<210>  2319
<211>  2808
<212>  DNA
<213>  homo sapiens

<400>  2319
gcgattggtg ggcggggggc cgggcctggg ccggcgggga gcggattggt cggaaagtag       60

gttagtggtg cgacatttag ggaaggcaga aagtaggtca gggacggagg tgcctgttta      120

cccgcgccgg actcaccgcc gccgccgccg cgggatccga gtgcgggcgc gggcgcgggc      180

gctcccggcg agccacggtg gtgctggcta gagtgtatac gtttggaccc aagcttaact      240

tttccaatgt ggaatcctgg gccttcattg gtttttggaa gaagctgacc gcctgaaaag      300

aaattataaa acatgaaaat cgctttgagg tgaccaagtc cagaggcccc taactcctcc      360

caagctggat ctggggtgta agaactgtga cttcagatca tccaatggca gaccagagaa      420

tggacatttc ttcaaccatc agtgatttca tgtccccggg ccccaccgac ctgctttcca      480

gctctcttgg taccagtggt gtggattgca accgcaaacg gaaaggcagc tccactgact      540

accaagaaag catggacaca gacaaagatg accctcatgg aaggttagaa tatacagaac      600

accaaggaag gataaaaaat gcaagggaag ctcacagtca gattgaaaag cggcgtcggg      660

ataaaatgaa cagttttata gatgaattgg cttctttggt accaacatgc aacgcaatgt      720

ccaggaaatt agataaactt actgtgctaa ggatggctgt tcagcacatg aaaacattaa      780

gaggtgccac caatccatac acagaagcaa actacaaacc aacttttcta tcagacgatg      840

aattgaaaca cctcattctc agggcagcag atggattttt gtttgtcgta ggatgtgacc      900

gagggaagat actctttgtc tcagagtctg tcttcaagat cctcaactac agccagaatg      960

atctgattgg tcagagtttg tttgactacc tgcatcctaa agatattgcc aaagtcaagg     1020

agcagctctc ctcctctgac accgcacccc gggagcggct catagatgca aaaactggac     1080

ttccagttaa aacagatata acccctgggc catctcgatt atgttctgga gcacgacgtt     1140

ctttcttctg taggatgaag tgtaacaggc cttcagtaaa ggttgaagac aaggacttcc     1200

cctctacctg ctcaaagaaa aaagatcgaa aaagcttctg cacaatccac agcacaggct     1260

atttgaaaag ctggccaccc acaaagatgg ggctggatga agacaacgaa ccagacaatg     1320

aggggtgtaa cctcagctgc ctcgtcgcaa ttggacgact gcattctcat gtagttccac     1380

aaccagtgaa cggggaaatc agggtgaaat ctatggaata tgtttctcgg cacgcgatag     1440

atggaaagtt tgtttttgta gaccagaggg caacagctat tttggcatat ttaccacaag     1500

aacttctagg cacatcgtgt tatgaatatt ttcaccaaga tgacatagga catcttgcag     1560

aatgtcatag gcaagtttta cagacgagag aaaaaattac aactaattgc tataaattta     1620

aaatcaaaga tggttctttt atcacactac ggagtcgatg gttcagtttc atgaaccctt     1680

ggaccaagga agtagaatat attgtctcaa ctaacactgt tgttttagcc aacgtcctgg     1740

aaggcgggga cccaaccttc ccacagctca cagcatcccc ccacagcatg gacagcatgc     1800

tgccctctgg agaaggtggc ccaaagagga cccaccccac tgttccaggg attccagggg     1860

gaacccgggc tggggcagga aaaataggcc gaatgattgc tgaggaaatc atggaaatcc     1920

acaggataag agggtcatcg ccttctagct gtggctccag cccattgaac atcacgagta     1980

cgcctccccc tgatgcctct tctccaggag gcaagaagat tttaaatgga gggactccag     2040

acattccttc cagtggccta ctatcaggcc aggctcagga gaacccaggt tatccatatt     2100

ctgatagttc ttctattctt ggtgagaacc cccacatagg tatagacatg attgacaacg     2160

accaaggatc aagtagtccc agtaatgatg aggcagcaat ggctgtcatc atgagcctct     2220

tggaagcaga tgctggactg ggtggccctg ttgactttag tgacttgcca tggccgctgt     2280

aaacactaca tgttgctttg gcaacagcta tagtatcaaa gtgcattact ggtggagttt     2340

tacagtctgt gaagcttact ggataaggag agaatagctt ttatgtactg acttcataaa     2400

agccatctca gagccattga tacaagtcaa tcttactata tgtaacttca gacaaagtgg     2460

aactaagcct gctccagtgt ttcctcatca ttgattattg ggctagctgt ggatagcttg     2520

cattaattgt atattttgga ttctgtttgt gttgaatttt ttaatcattg tgcacagaag     2580

catcattggt agcttttata tgcaaatggt catttcagat gtatggtgtt tttacactac     2640

aaagaagtcc cccatgtgga tatttcttat actaattgta tcataaagcc gtttattctt     2700

ccttgtaaga atcctttact ataaatatgg gttaaagtat aatgtactag acagttaaat     2760

atttttaata aatgtttccc ttgttctata aaaaaaaaaa aaaaaaaa                  2808


<210>  2320
<211>  2879
<212>  DNA
<213>  homo sapiens

<400>  2320
gcgattggtg ggcggggggc cgggcctggg ccggcgggga gcggattggt cggaaagtag       60

gttagtggtg cgacatttag ggaaggcaga aagtaggtca gggacggagg tgcctgttta      120

cccgcgccgg actcaccgcc gccgccgccg cgggatccga gtgcgggcgc gggcgcgggc      180

gctcccggcg agccacggtg gtgctggcta gagtgtatac gtttggaccc aagcttaact      240

tttccaatgt ggaatcctgg gccttcattg gtttttggaa gaagctgacc gcctgaaaag      300

aaattataaa acatgaaaat cgctttgagg tgaccaagtc cagaggcccc taactcctcc      360

caagctggat ctggggtgta agaactgtga cttcagatca tccaatggca gaccagagaa      420

tggacatttc ttcaaccatc agtgatttca tgtccccggg ccccaccgac ctgctttcca      480

gctctcttgg taccagtggt gtggattgca accgcaaacg gaaaggcagc tccactgact      540

accattcaca ggtcgaattt ggggagcaca atggctggag gtcagatgcc cactaggaga      600

tgctatgatt aatatagaaa gcatggacac agacaaagat gaccctcatg gaaggttaga      660

atatacagaa caccaaggaa ggataaaaaa tgcaagggaa gctcacagtc agattgaaaa      720

gcggcgtcgg gataaaatga acagttttat agatgaattg gcttctttgg taccaacatg      780

caacgcaatg tccaggaaat tagataaact tactgtgcta aggatggctg ttcagcacat      840

gaaaacatta agaggtgcca ccaatccata cacagaagca aactacaaac caacttttct      900

atcagacgat gaattgaaac acctcattct cagggcagca gatggatttt tgtttgtcgt      960

aggatgtgac cgagggaaga tactctttgt ctcagagtct gtcttcaaga tcctcaacta     1020

cagccagaat gatctgattg gtcagagttt gtttgactac ctgcatccta aagatattgc     1080

caaagtcaag gagcagctct cctcctctga caccgcaccc cgggagcggc tcatagatgc     1140

aaaaactgga cttccagtta aaacagatat aacccctggg ccatctcgat tatgttctgg     1200

agcacgacgt tctttcttct gtaggatgaa gtgtaacagg ccttcagtaa aggttgaaga     1260

caaggacttc ccctctacct gctcaaagaa aaaagatcga aaaagcttct gcacaatcca     1320

cagcacaggc tatttgaaaa gctggccacc cacaaagatg gggctggatg aagacaacga     1380

accagacaat gaggggtgta acctcagctg cctcgtcgca attggacgac tgcattctca     1440

tgtagttcca caaccagtga acggggaaat cagggtgaaa tctatggaat atgtttctcg     1500

gcacgcgata gatggaaagt ttgtttttgt agaccagagg gcaacagcta ttttggcata     1560

tttaccacaa gaacttctag gcacatcgtg ttatgaatat tttcaccaag atgacatagg     1620

acatcttgca gaatgtcata ggcaagtttt acagacgaga gaaaaaatta caactaattg     1680

ctataaattt aaaatcaaag atggttcttt tatcacacta cggagtcgat ggttcagttt     1740

catgaaccct tggaccaagg aagtagaata tattgtctca actaacactg ttgttttagc     1800

caacgtcctg gaaggcgggg acccaacctt cccacagctc acagcatccc cccacagcat     1860

ggacagcatg ctgccctctg gagaaggtgg cccaaagagg acccacccca ctgttccagg     1920

gattccaggg ggaacccggg ctggggcagg aaaaataggc cgaatgattg ctgaggaaat     1980

catggaaatc cacaggataa gagggtcatc gccttctagc tgtggctcca gcccattgaa     2040

catcacgagt acgcctcccc ctgatgcctc ttctccagga ggcaagaaga ttttaaatgg     2100

agggactcca gacattcctt ccagtggcct actatcaggc caggctcagg agaacccagg     2160

ttatccatat tctgatagtt cttctattct tggtgagaac ccccacatag gtatagacat     2220

gattgacaac gaccaaggat caagtagtcc cagtaatgat gaggcagcaa tggctgtcat     2280

catgagcctc ttggaagcag atgctggact gggtggccct gttgacttta gtgacttgcc     2340

atggccgctg taaacactac atgttgcttt ggcaacagct atagtatcaa agtgcattac     2400

tggtggagtt ttacagtctg tgaagcttac tggataagga gagaatagct tttatgtact     2460

gacttcataa aagccatctc agagccattg atacaagtca atcttactat atgtaacttc     2520

agacaaagtg gaactaagcc tgctccagtg tttcctcatc attgattatt gggctagctg     2580

tggatagctt gcattaattg tatattttgg attctgtttg tgttgaattt tttaatcatt     2640

gtgcacagaa gcatcattgg tagcttttat atgcaaatgg tcatttcaga tgtatggtgt     2700

ttttacacta caaagaagtc ccccatgtgg atatttctta tactaattgt atcataaagc     2760

cgtttattct tccttgtaag aatcctttac tataaatatg ggttaaagta taatgtacta     2820

gacagttaaa tatttttaat aaatgtttcc cttgttctat aaaaaaaaaa aaaaaaaaa      2879


<210>  2321
<211>  4071
<212>  DNA
<213>  homo sapiens

<400>  2321
tgattcgagc gggaagaggg gggtgggtgg gatcggtggg ggagaccatg acctccagct       60

acgggcacgt tctggagcgg caaccggcgc tgggcggccg cttggacagc ccgggcaacc      120

tcgacaccct gcaggcgaaa aagaacttct ccgtcagtca cctgctagac ctggaggaag      180

ccggggacat ggtggcggca caggcggatg agaacgtggg cgaggctggc cggagcctgc      240

tggagtcgcc gggactcacc agcggcagcg acaccccgca gcaggacaat gaccagctga      300

actcagaaga aaaaaagaag agaaagcagc gaaggaatag gacaaccttc aatagcagcc      360

agctgcaggc tttggagcgt gtctttgagc ggacacacta tcctgatgct tttgtgcgag      420

aagaccttgc ccgccgggtg aacctcaccg aggcgagagt gcaggtgtgg tttcagaacc      480

gaagagccaa gttccgcagg aatgagagag ccatgctagc caataaaaac gcttccctcc      540

tcaaatccta ctcaggagac gtgactgctg tggagcagcc catcgtacct cgtcctgctc      600

cgagacccac cgattatctc tcctggggga cagcgtctcc gtacagatcc tcgtccctcc      660

caagatgttg tttacacgag gggcttcata acggattcta acggaagaca ctgaaaagcg      720

ccatggctac ttattctgcc acatgtgcca acaatagccc tgcacagggc atcaacatgg      780

ccaacagcat tgccaacctg agactgaagg ccaaggaata tagtttacag aggaaccagg      840

tgccaacagt caactgagga aaaaaaataa ttaaacaggc ctaagaagaa atcaaaaacc      900

ataagacacc tatcctgctc tgttatttct tcatctgctg gggggaaaaa gtaaattaca      960

aacaaacaaa caaagcagaa ctaaaatatt gggaccatgg cagagaaaag caggagagga     1020

gcaaaatgaa aattagttaa caaatgttcc tcctccctct gggataccac caccacttgt     1080

ttctgtgtgt gtttattttg tttttctttc attcatgctt tgcttaatgt actccaggct     1140

tcttcagcta ggttcagccc acccaccccc atgattgtat gaagttttaa aaaaaactac     1200

agcagccaaa gaaactatat atatatatat atatatatat atccagaatg attgcctcta     1260

ctgtcctcat tgacttgttt gaaccttagt gccttaccct gtcctcttcc cagttctctt     1320

tatagaagct ctaggagctt tcgaaaagcc aaagtctttc tgaagaatct gtgctggaca     1380

gacataattc cctttctcat tgtctccatc tttgttggtc atggtaaggt ttttccatca     1440

gcctctgaaa aaatagttgt gcacaacatc tgctcactgg actgtctgat ccaatgtaat     1500

tggctgcgtc tggctaattc taagcactaa agtctacatc taagctatag atttaagctt     1560

gaagctacag attatatcac tatcaccacc acccctcacc ctatgcaatc aatcaatcaa     1620

tcatcttaag ttaaagatat ttgttgtctt tgaatgattt gctgtcacag actatttggt     1680

agaagaaata tttttcacct gagagaggaa gagaaatttc tctagtaaca caaagagtga     1740

gttctaaaag gcatgcccac atctctttcg tgccttaagg atagtgagat gcacacttat     1800

atatatactg tatatattta tatatttata tatatatttc atatatatat ataatattgc     1860

aagcttaagt ttgcaatttc ccaaacaata caaaaagcaa attacacacc ctcaccactg     1920

ttcttatctc tatagtgatg aaacattaat tagggatctt gctgcttttc tttttctaca     1980

cgaagttttc attaaagcca cagaataatt gatagggcag ctgtttgaga acaggtccca     2040

ttttcacatt agggctttaa atgaattaga aactatttga ggctataaaa atgtccttga     2100

gtttggagcc tgagctctgg tgaaatgctg atacatctga tctatcatgg gaattgcagt     2160

tagagagagt aaggaatacc atttagtcat ctatccgttc ttcacttagc aggaatatga     2220

aagaaaggca catgtttaag aggaatacct aaaggttttt ctaaattcca acatttaaaa     2280

ggcaattgtg ggctattttt attttttaat attttgaaat aaagtttagt gtctagggct     2340

gggagccagg actgatcttc catttctttt tctttgttcc cagccatgct tttgtaactt     2400

gccaggtgga cttgaccaac tacattacca tgctgtgcct cagtttaccc atttgtaaaa     2460

tgggattaat aatacttacc tacctcacag gggtgttgtg aggctctatt catttgctcc     2520

tttattcttt cctgtattct ctgtatgtcc agcactttgt agccatggga ggaaagggac     2580

tataaaagtg tacaatgtta atggaatgat acggtacctg aaagccttgt tttctagtaa     2640

gaaaatgcta ccttgctgta catacttata accttgtatt tggaaatgag aaataggttt     2700

atattttcag atctctcaaa aatcacatca tttgaccaaa gaataattta agacacatag     2760

aacagatttt tttaatttat attttcatcc tgaccagctt agttctaata atttttagtt     2820

gtgagtgatt aaaaaacttt ggatcaattt tggtcaaaca tgccaacttt gtagtctgag     2880

tgacaggcaa ggatttttgg gtttaagatg cacttttagc acacatttgt atttcccttg     2940

gcatatcaga ttgagctaat ggtgatgtta tttcaatcta acagccacca atctgaaatt     3000

gtatttcaaa tgttgattct gtagttcttt aaataataat gaagctcatc ttatacattt     3060

tgctttcacc aattgattcc ttcttctttt agcccactat taaaacattt cttactgaat     3120

ggttcatgta ggcttgctga acagcacgca ttacttgctt cctgaagagt tcccccattc     3180

atccatttgt cccattagtt gctgtggatt atcaagtttt gaaggaactg tacatcccaa     3240

cagactgaaa cattctaagt gaaatgagta taatccaagt aactggtgaa ctttggaggt     3300

ttggagcttg aagagaatgg ctaagaagat ttgaattata gggagggaac agaaatcata     3360

catgaaaagg ttttactgag aaggggaaaa ccttagatag agggacatgt gaaacaaaat     3420

catttgaaat tttgattcag acatccattt ccagtggcaa acagcaaagc ctgaacccat     3480

aaacccaaat gataggtgaa gttgggtggt tttatccaat gtctcaagca agcaatgtct     3540

gggaatatca tagagtaaca agtgctggtc agccaaagaa acattcactg ctggtgaacc     3600

aataccataa gcatgtatta tctaagcact tgatcaagaa atatacatgt tgtacaagct     3660

ctcaattttg ttcatttatt atcaaatttt taaaatacaa gtttggtatg tgatttggaa     3720

aagatgcctt ctggatctta agccagttgt cagtggaggt cctcagggct gcaaatgtca     3780

agacataacc ctgttcctca ccatcatgat accagataca ggtgaataca taggaactat     3840

ctgcctgtgt cctcaatctc ccttcaaaca agatgctgat ttgtagggta cttggcaggt     3900

taaattaaac cagaagaggt gacttaataa aaaagggaat gacatttagg gtataaagat     3960

ctcataagaa atgtaatatg taaattatat cttgctttat gttgtaaaat atacattgtt     4020

tgcgctagaa tagaaatgat ttcttttcaa taaaaagaaa gaaggactct a              4071


<210>  2322
<211>  3999
<212>  DNA
<213>  homo sapiens

<400>  2322
tgattcgagc gggaagaggg gggtgggtgg gatcggtggg ggagaccatg acctccagct       60

acgggcacgt tctggagcgg caaccggcgc tgggcggccg cttggacagc ccgggcaacc      120

tcgacaccct gcaggcgaaa aagaacttct ccgtcagtca cctgctagac ctggaggaag      180

ccggggacat ggtggcggca caggcggatg agaacgtggg cgaggctggc cggagcctgc      240

tggagtcgcc gggactcacc agcggcagcg acaccccgca gcaggacaat gaccagctga      300

actcagaaga aaaaaagaag agaaagcagc gaaggaatag gacaaccttc aatagcagcc      360

agctgcaggc tttggagcgt gtctttgagc ggacacacta tcctgatgct tttgtgcgag      420

aagaccttgc ccgccgggtg aacctcaccg aggcgagagt gcaggtgtgg tttcagaacc      480

gaagagccaa gttccgcagg aatgagagag ccatgctagc caataaaaac gcttccctcc      540

tcaaatccta ctcaggagac gtgactgctg tggagcagcc catcgtacct cgtcctgctc      600

cgagacccac cgattatctc tcctggggga cagcgtctcc gtacagcgcc atggctactt      660

attctgccac atgtgccaac aatagccctg cacagggcat caacatggcc aacagcattg      720

ccaacctgag actgaaggcc aaggaatata gtttacagag gaaccaggtg ccaacagtca      780

actgaggaaa aaaaataatt aaacaggcct aagaagaaat caaaaaccat aagacaccta      840

tcctgctctg ttatttcttc atctgctggg gggaaaaagt aaattacaaa caaacaaaca      900

aagcagaact aaaatattgg gaccatggca gagaaaagca ggagaggagc aaaatgaaaa      960

ttagttaaca aatgttcctc ctccctctgg gataccacca ccacttgttt ctgtgtgtgt     1020

ttattttgtt tttctttcat tcatgctttg cttaatgtac tccaggcttc ttcagctagg     1080

ttcagcccac ccacccccat gattgtatga agttttaaaa aaaactacag cagccaaaga     1140

aactatatat atatatatat atatatatat ccagaatgat tgcctctact gtcctcattg     1200

acttgtttga accttagtgc cttaccctgt cctcttccca gttctcttta tagaagctct     1260

aggagctttc gaaaagccaa agtctttctg aagaatctgt gctggacaga cataattccc     1320

tttctcattg tctccatctt tgttggtcat ggtaaggttt ttccatcagc ctctgaaaaa     1380

atagttgtgc acaacatctg ctcactggac tgtctgatcc aatgtaattg gctgcgtctg     1440

gctaattcta agcactaaag tctacatcta agctatagat ttaagcttga agctacagat     1500

tatatcacta tcaccaccac ccctcaccct atgcaatcaa tcaatcaatc atcttaagtt     1560

aaagatattt gttgtctttg aatgatttgc tgtcacagac tatttggtag aagaaatatt     1620

tttcacctga gagaggaaga gaaatttctc tagtaacaca aagagtgagt tctaaaaggc     1680

atgcccacat ctctttcgtg ccttaaggat agtgagatgc acacttatat atatactgta     1740

tatatttata tatttatata tatatttcat atatatatat aatattgcaa gcttaagttt     1800

gcaatttccc aaacaataca aaaagcaaat tacacaccct caccactgtt cttatctcta     1860

tagtgatgaa acattaatta gggatcttgc tgcttttctt tttctacacg aagttttcat     1920

taaagccaca gaataattga tagggcagct gtttgagaac aggtcccatt ttcacattag     1980

ggctttaaat gaattagaaa ctatttgagg ctataaaaat gtccttgagt ttggagcctg     2040

agctctggtg aaatgctgat acatctgatc tatcatggga attgcagtta gagagagtaa     2100

ggaataccat ttagtcatct atccgttctt cacttagcag gaatatgaaa gaaaggcaca     2160

tgtttaagag gaatacctaa aggtttttct aaattccaac atttaaaagg caattgtggg     2220

ctatttttat tttttaatat tttgaaataa agtttagtgt ctagggctgg gagccaggac     2280

tgatcttcca tttctttttc tttgttccca gccatgcttt tgtaacttgc caggtggact     2340

tgaccaacta cattaccatg ctgtgcctca gtttacccat ttgtaaaatg ggattaataa     2400

tacttaccta cctcacaggg gtgttgtgag gctctattca tttgctcctt tattctttcc     2460

tgtattctct gtatgtccag cactttgtag ccatgggagg aaagggacta taaaagtgta     2520

caatgttaat ggaatgatac ggtacctgaa agccttgttt tctagtaaga aaatgctacc     2580

ttgctgtaca tacttataac cttgtatttg gaaatgagaa ataggtttat attttcagat     2640

ctctcaaaaa tcacatcatt tgaccaaaga ataatttaag acacatagaa cagatttttt     2700

taatttatat tttcatcctg accagcttag ttctaataat ttttagttgt gagtgattaa     2760

aaaactttgg atcaattttg gtcaaacatg ccaactttgt agtctgagtg acaggcaagg     2820

atttttgggt ttaagatgca cttttagcac acatttgtat ttcccttggc atatcagatt     2880

gagctaatgg tgatgttatt tcaatctaac agccaccaat ctgaaattgt atttcaaatg     2940

ttgattctgt agttctttaa ataataatga agctcatctt atacattttg ctttcaccaa     3000

ttgattcctt cttcttttag cccactatta aaacatttct tactgaatgg ttcatgtagg     3060

cttgctgaac agcacgcatt acttgcttcc tgaagagttc ccccattcat ccatttgtcc     3120

cattagttgc tgtggattat caagttttga aggaactgta catcccaaca gactgaaaca     3180

ttctaagtga aatgagtata atccaagtaa ctggtgaact ttggaggttt ggagcttgaa     3240

gagaatggct aagaagattt gaattatagg gagggaacag aaatcataca tgaaaaggtt     3300

ttactgagaa ggggaaaacc ttagatagag ggacatgtga aacaaaatca tttgaaattt     3360

tgattcagac atccatttcc agtggcaaac agcaaagcct gaacccataa acccaaatga     3420

taggtgaagt tgggtggttt tatccaatgt ctcaagcaag caatgtctgg gaatatcata     3480

gagtaacaag tgctggtcag ccaaagaaac attcactgct ggtgaaccaa taccataagc     3540

atgtattatc taagcacttg atcaagaaat atacatgttg tacaagctct caattttgtt     3600

catttattat caaattttta aaatacaagt ttggtatgtg atttggaaaa gatgccttct     3660

ggatcttaag ccagttgtca gtggaggtcc tcagggctgc aaatgtcaag acataaccct     3720

gttcctcacc atcatgatac cagatacagg tgaatacata ggaactatct gcctgtgtcc     3780

tcaatctccc ttcaaacaag atgctgattt gtagggtact tggcaggtta aattaaacca     3840

gaagaggtga cttaataaaa aagggaatga catttagggt ataaagatct cataagaaat     3900

gtaatatgta aattatatct tgctttatgt tgtaaaatat acattgtttg cgctagaata     3960

gaaatgattt cttttcaata aaaagaaaga aggactcta                            3999


<210>  2323
<211>  4071
<212>  DNA
<213>  homo sapiens

<400>  2323
tgattcgagc gggaagaggg gggtgggtgg gatcggtggg ggagaccatg acctccagct       60

acgggcacgt tctggagcgg caaccggcgc tgggcggccg cttggacagc ccgggcaacc      120

tcgacaccct gcaggcgaaa aagaacttct ccgtcagtca cctgctagac ctggaggaag      180

ccggggacat ggtggcggca caggcggatg agaacgtggg cgaggctggc cggagcctgc      240

tggagtcgcc gggactcacc agcggcagcg acaccccgca gcaggacaat gaccagctga      300

actcagaaga aaaaaagaag agaaagcagc gaaggaatag gacaaccttc aatagcagcc      360

agctgcaggc tttggagcgt gtctttgagc ggacacacta tcctgatgct tttgtgcgag      420

aagaccttgc ccgccgggtg aacctcaccg aggcgagagt gcaggtgtgg tttcagaacc      480

gaagagccaa gttccgcagg aatgagagag ccatgctagc caataaaaac gcttccctcc      540

tcaaatccta ctcaggagac gtgactgctg tggagcagcc catcgtacct cgtcctgctc      600

cgagacccac cgattatctc tcctggggga cagcgtctcc gtacagatcc tcgtccctcc      660

caagatgttg tttacacgag gggcttcata acggattcta acggaagaca ctgaaaagcg      720

ccatggctac ttattctgcc acatgtgcca acaatagccc tgcacagggc atcaacatgg      780

ccaacagcat tgccaacctg agactgaagg ccaaggaata tagtttacag aggaaccagg      840

tgccaacagt caactgagga aaaaaaataa ttaaacaggc ctaagaagaa atcaaaaacc      900

ataagacacc tatcctgctc tgttatttct tcatctgctg gggggaaaaa gtaaattaca      960

aacaaacaaa caaagcagaa ctaaaatatt gggaccatgg cagagaaaag caggagagga     1020

gcaaaatgaa aattagttaa caaatgttcc tcctccctct gggataccac caccacttgt     1080

ttctgtgtgt gtttattttg tttttctttc attcatgctt tgcttaatgt actccaggct     1140

tcttcagcta ggttcagccc acccaccccc atgattgtat gaagttttaa aaaaaactac     1200

agcagccaaa gaaactatat atatatatat atatatatat atccagaatg attgcctcta     1260

ctgtcctcat tgacttgttt gaaccttagt gccttaccct gtcctcttcc cagttctctt     1320

tatagaagct ctaggagctt tcgaaaagcc aaagtctttc tgaagaatct gtgctggaca     1380

gacataattc cctttctcat tgtctccatc tttgttggtc atggtaaggt ttttccatca     1440

gcctctgaaa aaatagttgt gcacaacatc tgctcactgg actgtctgat ccaatgtaat     1500

tggctgcgtc tggctaattc taagcactaa agtctacatc taagctatag atttaagctt     1560

gaagctacag attatatcac tatcaccacc acccctcacc ctatgcaatc aatcaatcaa     1620

tcatcttaag ttaaagatat ttgttgtctt tgaatgattt gctgtcacag actatttggt     1680

agaagaaata tttttcacct gagagaggaa gagaaatttc tctagtaaca caaagagtga     1740

gttctaaaag gcatgcccac atctctttcg tgccttaagg atagtgagat gcacacttat     1800

atatatactg tatatattta tatatttata tatatatttc atatatatat ataatattgc     1860

aagcttaagt ttgcaatttc ccaaacaata caaaaagcaa attacacacc ctcaccactg     1920

ttcttatctc tatagtgatg aaacattaat tagggatctt gctgcttttc tttttctaca     1980

cgaagttttc attaaagcca cagaataatt gatagggcag ctgtttgaga acaggtccca     2040

ttttcacatt agggctttaa atgaattaga aactatttga ggctataaaa atgtccttga     2100

gtttggagcc tgagctctgg tgaaatgctg atacatctga tctatcatgg gaattgcagt     2160

tagagagagt aaggaatacc atttagtcat ctatccgttc ttcacttagc aggaatatga     2220

aagaaaggca catgtttaag aggaatacct aaaggttttt ctaaattcca acatttaaaa     2280

ggcaattgtg ggctattttt attttttaat attttgaaat aaagtttagt gtctagggct     2340

gggagccagg actgatcttc catttctttt tctttgttcc cagccatgct tttgtaactt     2400

gccaggtgga cttgaccaac tacattacca tgctgtgcct cagtttaccc atttgtaaaa     2460

tgggattaat aatacttacc tacctcacag gggtgttgtg aggctctatt catttgctcc     2520

tttattcttt cctgtattct ctgtatgtcc agcactttgt agccatggga ggaaagggac     2580

tataaaagtg tacaatgtta atggaatgat acggtacctg aaagccttgt tttctagtaa     2640

gaaaatgcta ccttgctgta catacttata accttgtatt tggaaatgag aaataggttt     2700

atattttcag atctctcaaa aatcacatca tttgaccaaa gaataattta agacacatag     2760

aacagatttt tttaatttat attttcatcc tgaccagctt agttctaata atttttagtt     2820

gtgagtgatt aaaaaacttt ggatcaattt tggtcaaaca tgccaacttt gtagtctgag     2880

tgacaggcaa ggatttttgg gtttaagatg cacttttagc acacatttgt atttcccttg     2940

gcatatcaga ttgagctaat ggtgatgtta tttcaatcta acagccacca atctgaaatt     3000

gtatttcaaa tgttgattct gtagttcttt aaataataat gaagctcatc ttatacattt     3060

tgctttcacc aattgattcc ttcttctttt agcccactat taaaacattt cttactgaat     3120

ggttcatgta ggcttgctga acagcacgca ttacttgctt cctgaagagt tcccccattc     3180

atccatttgt cccattagtt gctgtggatt atcaagtttt gaaggaactg tacatcccaa     3240

cagactgaaa cattctaagt gaaatgagta taatccaagt aactggtgaa ctttggaggt     3300

ttggagcttg aagagaatgg ctaagaagat ttgaattata gggagggaac agaaatcata     3360

catgaaaagg ttttactgag aaggggaaaa ccttagatag agggacatgt gaaacaaaat     3420

catttgaaat tttgattcag acatccattt ccagtggcaa acagcaaagc ctgaacccat     3480

aaacccaaat gataggtgaa gttgggtggt tttatccaat gtctcaagca agcaatgtct     3540

gggaatatca tagagtaaca agtgctggtc agccaaagaa acattcactg ctggtgaacc     3600

aataccataa gcatgtatta tctaagcact tgatcaagaa atatacatgt tgtacaagct     3660

ctcaattttg ttcatttatt atcaaatttt taaaatacaa gtttggtatg tgatttggaa     3720

aagatgcctt ctggatctta agccagttgt cagtggaggt cctcagggct gcaaatgtca     3780

agacataacc ctgttcctca ccatcatgat accagataca ggtgaataca taggaactat     3840

ctgcctgtgt cctcaatctc ccttcaaaca agatgctgat ttgtagggta cttggcaggt     3900

taaattaaac cagaagaggt gacttaataa aaaagggaat gacatttagg gtataaagat     3960

ctcataagaa atgtaatatg taaattatat cttgctttat gttgtaaaat atacattgtt     4020

tgcgctagaa tagaaatgat ttcttttcaa taaaaagaaa gaaggactct a              4071


<210>  2324
<211>  3999
<212>  DNA
<213>  homo sapiens

<400>  2324
tgattcgagc gggaagaggg gggtgggtgg gatcggtggg ggagaccatg acctccagct       60

acgggcacgt tctggagcgg caaccggcgc tgggcggccg cttggacagc ccgggcaacc      120

tcgacaccct gcaggcgaaa aagaacttct ccgtcagtca cctgctagac ctggaggaag      180

ccggggacat ggtggcggca caggcggatg agaacgtggg cgaggctggc cggagcctgc      240

tggagtcgcc gggactcacc agcggcagcg acaccccgca gcaggacaat gaccagctga      300

actcagaaga aaaaaagaag agaaagcagc gaaggaatag gacaaccttc aatagcagcc      360

agctgcaggc tttggagcgt gtctttgagc ggacacacta tcctgatgct tttgtgcgag      420

aagaccttgc ccgccgggtg aacctcaccg aggcgagagt gcaggtgtgg tttcagaacc      480

gaagagccaa gttccgcagg aatgagagag ccatgctagc caataaaaac gcttccctcc      540

tcaaatccta ctcaggagac gtgactgctg tggagcagcc catcgtacct cgtcctgctc      600

cgagacccac cgattatctc tcctggggga cagcgtctcc gtacagcgcc atggctactt      660

attctgccac atgtgccaac aatagccctg cacagggcat caacatggcc aacagcattg      720

ccaacctgag actgaaggcc aaggaatata gtttacagag gaaccaggtg ccaacagtca      780

actgaggaaa aaaaataatt aaacaggcct aagaagaaat caaaaaccat aagacaccta      840

tcctgctctg ttatttcttc atctgctggg gggaaaaagt aaattacaaa caaacaaaca      900

aagcagaact aaaatattgg gaccatggca gagaaaagca ggagaggagc aaaatgaaaa      960

ttagttaaca aatgttcctc ctccctctgg gataccacca ccacttgttt ctgtgtgtgt     1020

ttattttgtt tttctttcat tcatgctttg cttaatgtac tccaggcttc ttcagctagg     1080

ttcagcccac ccacccccat gattgtatga agttttaaaa aaaactacag cagccaaaga     1140

aactatatat atatatatat atatatatat ccagaatgat tgcctctact gtcctcattg     1200

acttgtttga accttagtgc cttaccctgt cctcttccca gttctcttta tagaagctct     1260

aggagctttc gaaaagccaa agtctttctg aagaatctgt gctggacaga cataattccc     1320

tttctcattg tctccatctt tgttggtcat ggtaaggttt ttccatcagc ctctgaaaaa     1380

atagttgtgc acaacatctg ctcactggac tgtctgatcc aatgtaattg gctgcgtctg     1440

gctaattcta agcactaaag tctacatcta agctatagat ttaagcttga agctacagat     1500

tatatcacta tcaccaccac ccctcaccct atgcaatcaa tcaatcaatc atcttaagtt     1560

aaagatattt gttgtctttg aatgatttgc tgtcacagac tatttggtag aagaaatatt     1620

tttcacctga gagaggaaga gaaatttctc tagtaacaca aagagtgagt tctaaaaggc     1680

atgcccacat ctctttcgtg ccttaaggat agtgagatgc acacttatat atatactgta     1740

tatatttata tatttatata tatatttcat atatatatat aatattgcaa gcttaagttt     1800

gcaatttccc aaacaataca aaaagcaaat tacacaccct caccactgtt cttatctcta     1860

tagtgatgaa acattaatta gggatcttgc tgcttttctt tttctacacg aagttttcat     1920

taaagccaca gaataattga tagggcagct gtttgagaac aggtcccatt ttcacattag     1980

ggctttaaat gaattagaaa ctatttgagg ctataaaaat gtccttgagt ttggagcctg     2040

agctctggtg aaatgctgat acatctgatc tatcatggga attgcagtta gagagagtaa     2100

ggaataccat ttagtcatct atccgttctt cacttagcag gaatatgaaa gaaaggcaca     2160

tgtttaagag gaatacctaa aggtttttct aaattccaac atttaaaagg caattgtggg     2220

ctatttttat tttttaatat tttgaaataa agtttagtgt ctagggctgg gagccaggac     2280

tgatcttcca tttctttttc tttgttccca gccatgcttt tgtaacttgc caggtggact     2340

tgaccaacta cattaccatg ctgtgcctca gtttacccat ttgtaaaatg ggattaataa     2400

tacttaccta cctcacaggg gtgttgtgag gctctattca tttgctcctt tattctttcc     2460

tgtattctct gtatgtccag cactttgtag ccatgggagg aaagggacta taaaagtgta     2520

caatgttaat ggaatgatac ggtacctgaa agccttgttt tctagtaaga aaatgctacc     2580

ttgctgtaca tacttataac cttgtatttg gaaatgagaa ataggtttat attttcagat     2640

ctctcaaaaa tcacatcatt tgaccaaaga ataatttaag acacatagaa cagatttttt     2700

taatttatat tttcatcctg accagcttag ttctaataat ttttagttgt gagtgattaa     2760

aaaactttgg atcaattttg gtcaaacatg ccaactttgt agtctgagtg acaggcaagg     2820

atttttgggt ttaagatgca cttttagcac acatttgtat ttcccttggc atatcagatt     2880

gagctaatgg tgatgttatt tcaatctaac agccaccaat ctgaaattgt atttcaaatg     2940

ttgattctgt agttctttaa ataataatga agctcatctt atacattttg ctttcaccaa     3000

ttgattcctt cttcttttag cccactatta aaacatttct tactgaatgg ttcatgtagg     3060

cttgctgaac agcacgcatt acttgcttcc tgaagagttc ccccattcat ccatttgtcc     3120

cattagttgc tgtggattat caagttttga aggaactgta catcccaaca gactgaaaca     3180

ttctaagtga aatgagtata atccaagtaa ctggtgaact ttggaggttt ggagcttgaa     3240

gagaatggct aagaagattt gaattatagg gagggaacag aaatcataca tgaaaaggtt     3300

ttactgagaa ggggaaaacc ttagatagag ggacatgtga aacaaaatca tttgaaattt     3360

tgattcagac atccatttcc agtggcaaac agcaaagcct gaacccataa acccaaatga     3420

taggtgaagt tgggtggttt tatccaatgt ctcaagcaag caatgtctgg gaatatcata     3480

gagtaacaag tgctggtcag ccaaagaaac attcactgct ggtgaaccaa taccataagc     3540

atgtattatc taagcacttg atcaagaaat atacatgttg tacaagctct caattttgtt     3600

catttattat caaattttta aaatacaagt ttggtatgtg atttggaaaa gatgccttct     3660

ggatcttaag ccagttgtca gtggaggtcc tcagggctgc aaatgtcaag acataaccct     3720

gttcctcacc atcatgatac cagatacagg tgaatacata ggaactatct gcctgtgtcc     3780

tcaatctccc ttcaaacaag atgctgattt gtagggtact tggcaggtta aattaaacca     3840

gaagaggtga cttaataaaa aagggaatga catttagggt ataaagatct cataagaaat     3900

gtaatatgta aattatatct tgctttatgt tgtaaaatat acattgtttg cgctagaata     3960

gaaatgattt cttttcaata aaaagaaaga aggactcta                            3999


<210>  2325
<211>  5569
<212>  DNA
<213>  homo sapiens

<400>  2325
agaacgagtt ccggtctggc cgaggcttgt ctcctaaaaa tagccccggt gtggggatcc       60

gtgcgcggat gtcccggcga gtcccgggct gaaagaggcg gctccgggcg gcgcgaagcg      120

ctggtggcgg gcccgggctg cggcgtgtgc gcgcccgcca gctgctccgg agatacggaa      180

ttgcattttg tgaaaaaaga acaagaattt tctgcaagga tcatatctaa gtgcactttt      240

tgctgatact tcatttctaa tcttgtagaa aatttcagct gtagcccttg gactagaagc      300

tgaaataaca gaagctgtgt acgatgcatt agggtattga agaaaattaa cttttgaatt      360

aaatatttgg aatataagga aataaggaaa gttgactgaa aatggggcgg aagaaaatac      420

aaatcacacg cataatggat gaaaggaacc gacaggtcac ttttacaaag agaaagtttg      480

gattaatgaa gaaagcctat gaacttagtg tgctctgtga ctgtgaaata gcactcatca      540

ttttcaacag ctctaacaaa ctgtttcaat atgctagcac tgatatggac aaagttcttc      600

tcaagtatac agaatataat gaacctcatg aaagcagaac caactcggat attgttgagg      660

ctctgaacaa gaaggaacac agagggtgcg acagcccaga ccctgatact tcatatgtgc      720

taactccaca tacagaagaa aaatataaaa aaattaatga ggaatttgat aatatgatgc      780

ggaatcataa aatcgcacct ggtctgccac ctcagaactt ttcaatgtct gtcacagttc      840

cagtgaccag ccccaatgct ttgtcctaca ctaacccagg gagttcactg gtgtccccat      900

ctttggcagc cagctcaacg ttaacagatt caagcatgct ctctccacct caaaccacat      960

tacatagaaa tgtgtctcct ggagctcctc agagaccacc aagtactggc aatgcaggtg     1020

ggatgttgag cactacagac ctcacagtgc caaatggagc tggaagcagt ccagtgggga     1080

atggatttgt aaactcaaga gcttctccaa atttgattgg agctactggt gcaaatagct     1140

taggcaaagt catgcctaca aagtctcccc ctccaccagg tggtggtaat cttggaatga     1200

acagtaggaa accagatctt cgagttgtca tccccccttc aagcaagggc atgatgcctc     1260

cactaaatac ccaaaggatc agtagttctc aagccactca acctcttgct accccagtcg     1320

tgtctgtgac aaccccaagc ttgcctccgc aaggacttgt gtactcagca atgccgactg     1380

cctacaacac tgattattca ctgaccagcg ctgacctgtc agcccttcaa ggcttcaact     1440

cgccaggaat gctgtcgctg ggacaggtgt cggcctggca gcagcaccac ctaggacaag     1500

cagccctcag ctctcttgtt gctggagggc agttatctca gggttccaat ttatccatta     1560

ataccaacca aaacatcagc atcaagtccg aaccgatttc acctcctcgg gatcgtatga     1620

ccccatcggg cttccagcag cagcagcagc agcagcagca gcagcagccg ccgccaccac     1680

cgcagcccca gccacaaccc ccgcagcccc agccccgaca ggaaatgggg cgctcccctg     1740

tggacagtct gagcagctct agtagctcct atgatggcag tgatcgggag gatccacggg     1800

gcgacttcca ttctccaatt gtgcttggcc gacccccaaa cactgaggac agagaaagcc     1860

cttctgtaaa gcgaatgagg atggacgcgt gggtgaccta aggcttccaa gctgatgttt     1920

gtacttttgt gttactgcag tgacctgccc tacatatcta aatcggtaaa taaggacatg     1980

agttaaatat atttatatgt acatacatat atatatccct ttacatatat atgtatgtgg     2040

gtgtgagtgt gtatgtgtgg gtgtgtgtta catacacaga atcaggcact tacctgcaaa     2100

ctccttgtag gtctgcagat gtgtgtccca tggcagacaa agcaccctgt aggcacagac     2160

aagtctggca cttccttgga ctacttgttt cgtaaagata accagttttt gcagagaaac     2220

gtgtacccat atataattct cccacactag cttgcagaaa cctagagggc cccctacttg     2280

ttttatttaa ctgtgcagtg actgtagtta cttaagagaa aatgctttgt agaacagagc     2340

agtagaaaag caggaaccaa gaaagcaata ctgtacataa aatgtcattt atattttcca     2400

acctggcatg ggtgtctgtt gcaaaggggt gcatgggaaa gggctgttga tattaaaaac     2460

aaacaaaaca aaaaagcccc acacataact gttttgcacg tgcaaaaatg tattgggtca     2520

agaagtgatc tttagctaat aaagaaagag aatagaaaac acgcatgaga tattcagaaa     2580

atactagcct agaaatatag agcattaaca aagtaaaatt aatatattaa gttataattg     2640

gaatatgtca gaagtttctt tttacattca tatcttaaaa attaaagaaa ctgattttag     2700

ctcatgtata ttttatatga aagaaaacac ccttatgaat tgatgactat atataaaatt     2760

atattcacta cttttgaaca cattctgcta tgaattattt atataagcca aagctatatg     2820

ttgtaacttt tttttagaga atagctttat cttggtttaa ctctttagtt ttattttaag     2880

aggggaaaac aaaaatatct tgcaagcaga accttggaaa aaaaaagcca tgaacactta     2940

ttctaaatgt aaattaaaag ttgagccaaa ctctttgtgt atatagcatc ttaaatatat     3000

tatcaccttt gatgtaagta cctatgtatt gtatggtcac cagattaaaa agtatatttt     3060

tgtggattgc cgccaatctg gggggaaaag gcgaggtcct ttattaagta ttcactgttt     3120

aatatttact attttgttaa atatactgta ctttggattt taattattag cccagttttt     3180

tcagaggatt gtataaaggg gtttctcccc tcactggtgg tgaatgtgtg atgttacatt     3240

gtaatctttg tgctgtatgg gttgagcatc attatatatt ttgtatgtgt acataaatag     3300

caaagtggca aaaaaaattg gtgttaagtt catcctgcat aagtataaaa tgtgttgtaa     3360

cagattttgt aaggcattat ttaaaacttg ccttttgtga ggaaaaaatg tagtagaaaa     3420

agctgaccta atttaattaa tattagagaa aatggcaaaa tagtagatga gcacaaaggt     3480

tttataagtg gtaaatgatt aggggaaaat aatcatgggg aaagggatct tttttccttg     3540

accctctgaa aacagaacga tgcagctggt tacaaaatcc taccgttatc agctcttctg     3600

cacattgcag tgatgctttg gtatgcgggg agaaacactc ttagggtgct ggtccttggc     3660

atgactcttg ccattctaat tggaattagt gccaccctca gcttggattt tgaacaaggc     3720

cttattcttt caggaagaca actaatggat gatagcaagt tcatccactt actgggcttg     3780

tgccatgagc aaaattcaaa gtcctgtata tctttcattg tagattttta aatactcctt     3840

ttcctaaaaa actcaagggt ttaaaaattg ctattttata ttttaaatga tattgagcag     3900

ctacctacaa tttctatgta cattttgttc cccccccccc accccccccc caaattacgt     3960

tccttttgac attttcctca tctgctgttt gtgacaagtc atcagccaga tttcctgact     4020

gacacatagg tatgatcagt gcaggagaga cctgcgcacc acaggctgca aactggaggt     4080

tctgttctca tggcagtttg ggcagtaact tttgagagag gccaaaaaaa ggaggatgac     4140

atgctgtctc ctctcttcag tatagacatt aggctcttat tcagaaagga tttttcttta     4200

aaaatgtact tactttactg aactacttac aggcacattt cttcataagg ccacacctaa     4260

tccaaacaag acagtctccc aacactgaag ttccaaaata atccttacca ctttgtaaac     4320

catttatagc tttgaaagtg ttaagtgatt ccttcgttat tatttatgca tgttcatgaa     4380

cttctgctgt acattggaat aggagttaac acattcacat ttactgtcta ttttcttgtg     4440

tgccttatga gatggctttt ctgactgtat ctcaatagtc tttctttcta tgcaggttta     4500

taatcagtac aactactgtt ttctaaaata ctactactca aggctcggag tttgtattta     4560

aattacactg accaagtaac aatgtattcc atttcaggaa ctgaatattt gactgttaac     4620

ctttttccca tacgtccagt gtggcatgga gcatatggac ttgacagaca tctctcaccc     4680

agacgcccac gtgtgaacac acccacatcc acatctctgg gtggaaacca gcctagagag     4740

gggacgacgc taatggtgtt gctttagaac cgtcttttct taccctttta gactcgtgtt     4800

ttgtatgaga caccattgca agaaaatttt atccctccag aagtatttta ttactaaaga     4860

acaaaagcaa aaaaagctta aattgcactg gttaaagtac agtttccaac agctgtcctt     4920

cctcagtact ctaatggcca ctccaccgcg agtggaagtc actgttgtgt gtacacaggt     4980

ggtcccaatc aaaactccat cttttgagcc caattatgtc cattttgtta tagactaaat     5040

caggggtttg ttctacaaga acaatacatg ttttaccctt tcctttaact agaaggataa     5100

ctagtaatgc atcaacataa tttctgtatt aaccatcatg cgcacaagaa atacatagta     5160

aataaggaag ctgaaaactc ctggcattgg atcttaagct agatgattag aatgtgaaaa     5220

agattttaca aatgtaaaac ttctatttct ctgtagaaac tttcttcact ttgctgtgca     5280

agaagacact gctttgctat atttaaaatg gcttttttaa aagagattta tgtatttggt     5340

aaatgtttgt agtcaacagt tcacacaaga agctgtacac ggtttgatca tgtaaaaccg     5400

tttggcggca caagctggac tttgttgcca tccttgagat gaacctttta agaaaaataa     5460

gttaatctca atttttccct gaatgtgttg tttttcttca ttatacaata aatataatag     5520

tgaacttttt atcaaatggt gaagacaatg ctaaaaaaaa aaaaaaaaa                 5569


<210>  2326
<211>  7689
<212>  DNA
<213>  homo sapiens

<400>  2326
acccgccccc accccctcca gcatctcggg ccagacagag aaaaccttgt tcaagtttgc       60

agcaagtact ttcccggtgc gcaaaactgg gcgactggga acgcgttgag acgttcctct      120

ttcccgcttc tccaccttta cgcctgaaag aagactccca aagattgctt tcttctggga      180

cgctgcttgg acgctaaccg cgttgattgg aacagatttt gtgtcttggc tggctttggg      240

tgaagaccgg ggagaaaagg ttgcgctgcg attctcaaga tctctggacc tggattatca      300

ttgcaaatcc attaaagaag gagaagcaag cggatttcag agaggttgtt cttcagaaaa      360

aaatggttat ttctttgaac tcatgcctga gctttatttg tttattgtta tgccactgga      420

ttgggacagc atcacctctg aatcttgaag accctaatgt gtgtagccac tgggaaagct      480

actcagtgac tgtgcaagag tcatacccac atccctttga tcaaatttac tacacgagct      540

gcactgacat tctaaactgg tttaaatgca cgcggcacag agtcagctat cggacagcct      600

atcgacatgg ggagaagact atgtataggc gcaagtctca gtgttgtcct ggattttatg      660

aaagcgggga aatgtgtgtc ccccactgtg ctgataaatg tgtccatggt cgctgtattg      720

ctccaaacac ctgtcagtgt gagcctggct ggggagggac caactgctcc agtgcctgcg      780

atggtgatca ctggggtccc cactgcacca gccggtgcca gtgcaaaaat ggggctctgt      840

gcaaccccat caccggggct tgccactgtg ctgcgggctt ccggggctgg cgctgcgagg      900

accgctgtga gcagggcacc tatggtaacg actgtcatca gagatgccag tgccagaatg      960

gagccacctg cgaccacgtc acgggggaat gccgctgccc accaggatac accggagcct     1020

tctgtgagga tctttgtcct cctggtaaac atggtccaca gtgtgagcag agatgccctt     1080

gtcaaaatgg aggagtgtgt catcacgtca ctggagaatg ctcttgccct tctggctgga     1140

tgggcacagt gtgtggtcag ccttgccccg agggtcgctt tggaaagaac tgttcccaag     1200

aatgccagtg ccataatgga gggacgtgtg atgctgccac aggccaatgt cattgcagtc     1260

caggatacac aggggaacgg tgccaggatg agtgtcctgt tgggacctat ggcgttctct     1320

gtgctgagac ctgccagtgt gtcaacggag ggaagtgtta ccacgtgagc ggcgcatgcc     1380

tctgtgaagc aggctttgct ggcgagcgct gcgaagcacg cctgtgtcct gaggggctct     1440

acggcatcaa atgtgacaaa cggtgtccct gccacctgga aaacactcat agctgtcacc     1500

ccatgtctgg agagtgtgcc tgcaagccgg gctggtcagg actctactgt aatgagacat     1560

gttctcctgg attctacggg gaagcttgcc agcagatctg cagctgccaa aatggggcag     1620

actgtgacag tgtgactgga aagtgcacct gtgccccagg attcaaagga attgactgct     1680

ctaccccatg ccctctggga acctatggga taaactgttc ctctcgctgt ggctgtaaaa     1740

atgatgcagt ctgctctcct gtggacgggt cttgtacttg caaggcaggc tggcacgggg     1800

tggactgctc catcagatgt cccagtggca catggggctt tggctgtaac ttaacatgcc     1860

agtgcctcaa cgggggagcc tgcaacaccc tggacgggac ctgcacgtgt gcacctggat     1920

ggcgcgggga gaaatgcgaa cttccctgcc aggatggcac gtacgggctg aactgtgctg     1980

agcgctgcga ctgcagccac gcagatggct gccaccctac cacgggccat tgccgctgcc     2040

tccccggatg gtcaggtgtc cactgtgaca gcgtgtgtgc tgagggacgc tggggcccca     2100

actgctccct gccctgctac tgtaaaaatg gggcttcatg ctcccctgat gatggcatct     2160

gcgagtgtgc accaggcttc cgaggcacca cttgtcagag gatctgctcc cctggttttt     2220

atgggcatcg ctgcagccag acatgcccac agtgcgttca cagcagcggg ccctgccacc     2280

acatcaccgg cctgtgtgac tgcttgcctg gcttcacagg cgccctctgc aatgaagtgt     2340

gtcccagtgg cagatttggg aaaaactgtg caggaatttg tacctgcacc aacaacggaa     2400

cctgtaaccc cattgacaga tcttgtcagt gttaccccgg ttggattggc agtgactgct     2460

ctcaaccatg tccacctgcc cactggggcc caaactgcat ccacacgtgc aactgccata     2520

atggagcttt ctgcagcgcc tacgatgggg aatgtaaatg cactcctggc tggacagggc     2580

tctactgcac tcagagatgt cctctagggt tttatggaaa agattgtgca ctgatatgcc     2640

aatgtcaaaa cggagctgac tgcgaccaca tttctgggca gtgtacttgc cgcactggat     2700

tcatgggacg gcactgtgag cagaagtgcc cttcaggaac atatggctat ggctgtcgcc     2760

agatatgtga ttgtctgaac aactccacct gcgaccacat cactgggacc tgttactgca     2820

gccccggatg gaagggagcg agatgtgatc aagctggtgt tatcatagtt ggaaatctga     2880

acagcttaag ccgaaccagt actgctctcc ctgctgattc ctaccagatc ggggccattg     2940

caggcatcat cattcttgtc ctagttgttc tcttcctact ggcattgttc attatttata     3000

gacacaagca gaagggaaag gaatcaagca tgccagcagt tacctacacc cctgctatga     3060

gggtcgtcaa tgcagattat accatttcag gaacccttcc tcacagcaat ggtggaaacg     3120

ctaatagcca ctacttcacc aatcccagtt accacacgct cacccagtgt gccacatccc     3180

ctcacgtcaa caacagggac aggatgactg tcacgaagtc aaaaaacaat caactgtttg     3240

tgaatcttaa aaatgtgaac cctgggaaga gaggccctgt gggggactgc actgggacat     3300

tgccggctga ctggaaacat ggcggctacc tcaacgagct cggtgctttt ggacttgaca     3360

gaagctatat gggaaaatcc ttaaaagacc tgggaaagaa ttctgaatat aattcaagta     3420

actgctccct aagcagttct gagaacccat atgccactat taaagaccca cctgtactta     3480

tcccgaaaag ctcagagtgt ggttatgtgg agatgaaatc gccggcacga agagattccc     3540

catatgcaga gatcaataac tcaacttcag ccaacaggaa tgtctatgaa gttgaaccta     3600

cagtgagtgt tgtccaagga gtattcagca ataatgggcg tctctcccag gatccatatg     3660

acctcccaaa gaacagtcac atcccttgtc attatgacct gctgccagtc cgagacagtt     3720

catcctcccc taagcaagag gacagtggtg gtagcagcag caacagcagc agcagcagtg     3780

aatgacacca aaggaccgct tggtagccac tggaaccctt tccagaactg ctgtttggtt     3840

cttctccatc ctcaattttg ccactttcat gtgaatgtta gtcaattcgg tgggcaattt     3900

ttggacatga accagaaagc tgaaagctga ggctgacacg gactgtaggt gctttttgtt     3960

caggtggatt cgaaggagtt agagatgtga tttcccattg ctgttagttt tagaactata     4020

cccgtgaagc atgacttatt gtaagatgtt ggctgaaagc atgaacttgc agaactccct     4080

cggagacgca ggttgcagtg gacattggga ttgttgcttg aaaaattaaa atttgaatat     4140

tttctctctc atttgcatca tacagctcta cctaggattg tacagtttac cataaaattt     4200

acttcatgaa agtgggaatc actgaacatg tagaagacaa ggaacatatt gttaactcct     4260

gattcttaac tttattcaac tggactcaga attgtaggga taatatgaat gcaggaggaa     4320

acattctgtc aggcggtatg actggacaga ctttgaatat actctaaaag tggacagaaa     4380

atttacgaaa atcttagatt ttgtttagaa tgagaaaata tacaattaga attattttag     4440

aaatagtagg aagtattgca gaagtcaata cacaaatgtg ccaggcagag gtggttttct     4500

ctgtttgact ctcaaccaac ttcagatcta tgacattatt ctgatcactg gctccatcat     4560

acatattcac cacttgagat tcataacata tcaatagtta tttcataaat atagaaatga     4620

aataatttta tttttgacag actggatgga atgagtgtgt aatgattgat aaaggttgta     4680

aattttaaat gcaagatgac gcttacgttc tgtaaaccat tagtaataca tgctgtaata     4740

tagaattagt ggaacatttt gattaatctt tccctagaag tgactgaaat atttttgtgc     4800

atatttgaga aagggaactt tccttttatt aattgtcaat ttagagaaac tatgcttaag     4860

ctggtctttt gcattgctaa tgtgacatgt acccaacttt tcattaattt gtatttccat     4920

ttttaaattg catattctat gttttgtagt gtttggattg ttaatgaaaa aatattatat     4980

gttcgttatt ccttgtatta ttgccactta tcttttgctt gataaaaatg cgttgttctt     5040

ttttcttttg gagggacaag atgaaaatat ataatttgaa ttgattaaaa ttggtcgtta     5100

ctaaaatagt atagtaacca caagtgattg gcttataaat gaagtagaaa tgctttttaa     5160

tattccaaaa tagagttcct tttgatctgt tggtgctgag ccttggttaa accagggaga     5220

aggggagcag aaaggaaacg ttgttactga tgagtaccac agactcatct taaaaaaaac     5280

tctcattatg gtgatcatag aattgaccat ccaaactggg acactcttga gagtaaatgg     5340

agggcattat taataattat cttgtaatga acttaaatct ggactgttcc aggcaaacca     5400

gacttatctt gcaatatgag aatgctgaca caatgcagga aagccagttt cccttttgtt     5460

gatctacttg accaagcaaa ggggctgaaa aactgaataa ggaaacaact ttataagaga     5520

aacagtggtc ttcaatcttt taaagacatg aaatcctata tggcattctg tctcagtgag     5580

tcagttaaca aatacgtatg tgcaaccctt ctgctagtag tgcacataag tgattatccc     5640

tgccaggtat cgagttggaa tatccagtta tttcatgtca cacatcggca cgtatgatgg     5700

tggtttggtc agatggataa tacagcagac acacttagaa cactcactgc actggtggct     5760

gttcattttg aggaactcca aagtcaattc aaggaaataa ggaatgacct ggaacaggcc     5820

ttagaaacaa ttgatttatt ccaatagtta accactggct ggctcccaac tctaggtgat     5880

aggcatctaa ttgagacatg tgtgagtcaa tagccatcgg ggtccttttt ggtgagaaga     5940

aataagacat tttctccctt ttaaagatca tctcttcaga gctgcatggt aaatttgaat     6000

ttccccattg ttctctagag ctaggtcaaa aaaacaactg tttcttttct tattccacta     6060

ttaataaatt gaaagcttgc tgtacaaagg caacagcaac ttaaaaaaga aaatctggac     6120

aatagatgtg gactccaagg ggccactgcc atcccttcct gtgtgctctt tttgacaagt     6180

aaatcactcc agttagctga tgtcctgaaa tgacatttgt acctgaggca attcttatta     6240

gagcttactc aggacttttc aaacatcagg acacacatag caatttggat gttgtaaaac     6300

tacgtgttac atttggagag gtcttgttga gaaggcaaaa ttttctaaat attttgatat     6360

caatttgggt aaagaaagga atacttttgt tagaatgaga attaaagaga aaacaaaaga     6420

atcttggcaa aattttccct ctgaaattac aaactttagg aacttttcca gatgtatcga     6480

atttaatttg acattgatgt cactcttcat accaagtgaa tctattctca tgaactttga     6540

acccatgtta attttggacc ctataactaa tttcctttct gtatcccatg gtggtcaaag     6600

cagtaaagga gtttagagat acttagcaaa tgccattcat atagtattgt tagccaaact     6660

attattcctt ccttagaagt tgatgtatca gaaaatttat aagttatttg tatttatata     6720

taagtacatc agaacttgcc cacatgataa ctcatgtttg ctttaataag gaaaatatgt     6780

tatttgaggt taattatatg atagtgagga acattttaca attatttaca gtgtttgaca     6840

ttaattgctg tcctatgata cagtagtaat gttaacagag agtttaatat gtttagcatt     6900

atctttatgg aatttatatt caccaatttc aggaaaacca accatagaac tttataatag     6960

gacagttata acctgactga accaaatcca tcagcataat gactgtgtgt tctgagaaat     7020

gcaaacaact ttatgaaagt gtggtcatct tgacccccaa agagccacag tagctgtcaa     7080

ttattgagat ttttaaatgg taaatattgc aaaagttaaa caagggtacc acaatatcat     7140

ttataattga tgtcaatatt agtagtccac tttatgctta aaataaaatc ataaaaaatc     7200

aagttttaag gttatatttt ttaaaataat gaattttcta tctctaggca acatgtcttt     7260

attattcaag ctgaatgttt aagagagatt ttggtcttaa aggcttcaca tcatgaaagt     7320

gtacatgcat atgcaagtgt gaattacgtg gtatggatgt ttgcttgttt attaactaaa     7380

gatgtacagc aaactgcccg tttagagtcc tgttaatatt gatgtcctaa cactgggtct     7440

gcttatgcta gttcagtatt tggtctaggc ttcattttga tatgactgaa ttgcaatcta     7500

tatttttaaa aagaaaaatc aaaatacatt agggtttact tggttgtggc aaacaaacaa     7560

aaaatgcttt cagtgttgaa atatctctat tttccaaaga tgataaactt tcatcgttct     7620

tagcctacat tgtcatttat atcaccaaat gagtttatag attaatgcaa taaactttct     7680

aataaaaaa                                                             7689


<210>  2327
<211>  4651
<212>  DNA
<213>  homo sapiens

<400>  2327
actcggctgt tttcgctgat gcgggcagct tgggggccgc cgccgctaaa cagacgcttt       60

cctttttaat tttttttcca tgtgttcact tccgggtccg gcgtcgatcc ggatgcccga      120

ggcagaagga tgtttgacct ccggataagc gaggcgctgc tgtgcattca ttccgggctg      180

catcggtggc gacagcagag gctcgggcgg cgactctccg gccagcggcg gcggtaggag      240

gcaccagcgg cagtgcaggg accgaatccg agcagcgctg cgttacctct ctctctcgct      300

ccttcccccc tacctcgctc gctcgctcgc tcgctccctg cgtggctcgc tttcctcctc      360

cggccgccgg cgggtgtgat gtgccgccgc cgctgccccc gccggcgctg acggactggg      420

ggcgccgccc gcgcccggga ccgacccctc tgctcgcggc cgcgcctttg agctctctat      480

caatatcagc tcacatcatt gaaaagataa ttttgaagac atgttttgct gaaaagacac      540

taagaaaaat tttacgaatg ggatgaacat gctccagtta attgactacc tactgcaatt      600

tgaatgttaa cattacccat ctggtacagt tacctagtga tgtacctatt ttcacaatac      660

cctgtttcag tgtgcttgtc ttgattaaag aattcaaagt ggagtaccgc aaacttgata      720

tggaaaataa aaagaaagac aaggacaaat cagatgatag aatggcacga cctagtggtc      780

gatcgggaca caacactcga ggaactgggt cttcatcgtc tggagtttta atggttggac      840

ctaactttag agttggaaaa aaaattggat gtggcaattt tggagaatta cgattaggga      900

aaaatttata cacaaatgaa tatgtggcaa ttaagttgga gcccatgaaa tcaagagcac      960

cacagctaca tttggaatac agattctata agcagttagg atctggagat ggtatacctc     1020

aagtttacta tttcggccct tgtggtaaat acaatgctat ggtgctggaa ctgctgggac     1080

ctagtttgga agacttgttt gacttgtgtg acagaacatt ttctcttaaa acagttctca     1140

tgatagctat acaactgatt tctcgcatgg aatatgtcca ttcaaagaac ttgatataca     1200

gagatgtaaa acctgagaac ttcttaatag gacgaccagg aaacaaaacc cagcaagtta     1260

ttcacattat agattttggt ttggcaaagg aatatattga tccggagaca aagaaacaca     1320

taccatacag agaacacaag agccttacag gaacagctag atatatgagc ataaacacac     1380

atttaggaaa agaacaaagt agaagagacg atttagaagc tttaggtcat atgttcatgt     1440

attttctgag aggcagtctt ccttggcaag gcttaaaggc tgacacatta aaggagaggt     1500

atcagaaaat tggagataca aaacgggcta caccaataga agtgttatgt gaaaattttc     1560

cagaaatggc aacatatctt cgttatgtaa gaaggctaga tttttttgaa aaaccagact     1620

atgactactt aagaaagctt tttactgact tgtttgatcg aaaaggatat atgtttgatt     1680

atgaatatga ctggattggt aaacagttgc ctactccagt gggtgcagtt cagcaagatc     1740

ctgctctgtc atcaaacaga gaagcacatc aacacagaga taagatgcaa caatccaaaa     1800

accaggttgt aagttctaca aatggagagt taaacacaga tgaccccacc gcaggacgtt     1860

caaatgcacc catcacagcc cctactgaag tagaagtgat ggatgaaacc aactgccaga     1920

aagtgttgaa catgtggtgc tgctgttttt tcaaacgaag gaaaaggaaa accatacagc     1980

gccacaaatg actctggaca cagacagatc ctggggagtt acttacatgt tcatctgctg     2040

tcttgtgatt aaaatcatct ctgtagtgac cacgtatatt ttcaaggact cactcttaga     2100

aacaaaaatg tcatactttc atacttcatt ttgtggttgt cttacattct ttttcttttt     2160

ttttttttct ctaatttaac ctttatggaa gctttaaagt tttgtcaaaa catgagtgct     2220

ttgcccatca gtgaatggaa tggaccaatg aggtggtatc aatgaatata gttccataga     2280

acattttcca gaagttcttc tgttgtagaa agcagtacag tatcttaagt gtcaaccagt     2340

tatataccta atctggtttt ttataacttc tgtaagagca taatcaaaca ggaattttct     2400

tttctcagtg gataatacaa cagagaaaac agagttgccc aaatatttaa aagaagttat     2460

tccttgagaa gttcatattt tgtgacatct gcattgattt cagtattact gatggtactg     2520

ttattcataa gtcatattaa cattctctcc gtgaaatcat ggtacagtca ctgcccagag     2580

gtactgagga aaaagcaata tgggttcggc agatggtggt ggtaaaatga atcttaagga     2640

gtgtggtaaa tatgtgctcc gcttttgttg catcactatg tgaagtactg tgttgcagaa     2700

gtggcaaaag cgcttatttt taaaaatgca aaatatttgt acaatgtaac tttatgcttc     2760

caaataataa tgtatgttag acagcaagaa atgaatactt taaaaagtga tgtatgttgg     2820

agttataaag aaatacacta aggagaggta gtaaatgtga accttgttgc agtgtataag     2880

gtggaagcct aaagaaatct caccgaaact tactgctgaa tgattacatt ctcccttaag     2940

cagaaaactt tggatgtgcc atgcaatggt gtctgtgtaa ttattttgct ctttgattaa     3000

aaaaaagacc cccagcaata aaaagtgggt cactctatgc cctctgtgca cattagtctc     3060

ttgtattcaa ctttgctgat tctctggaat tttcctactc tttagcataa ttttgatgat     3120

tgaaaaatat tttggaaagg atgggtcagg tgctttgcct ccatagtctt ttgaagtgcc     3180

tgcatatgaa caacaacaac aacaacaaaa aattctgtaa aaaaggaagc ccattccact     3240

tttcaagtat gctttgtttt aagccataaa gacacacatg tagttttgtc acattctact     3300

agccaaaatt ttcaagaagg gttaaaacaa agactggcta gaaagataat tattttgaat     3360

aaatctcata ttcatctttc atttatataa ttgttactta ttcctcccat gcagtctctt     3420

cgttgtcttt aagtgtgtgc ctccaggcat gcttatttat ttttattgtc tcaaggtaac     3480

atttaagatg tatattaaag taaagctaca tttttttact tcattattgc atttacaggg     3540

atttaattgt actttgtaat ttatttttct tattagccaa aagtttaatg catttttttt     3600

tgatgaatta ggcacccaca tgaacaccac aaatcaggac attgtttatc attgttgcta     3660

tgaatcctat gaatgatctt ttttttattt taaagaccta cacttaacct acaaaacatt     3720

tgctgtataa tttggtcaac agtttctatc tatctgtata ctgtcatgat gtcttaaact     3780

gcaggagtta catactgagt ttatattttt atttgctttg agcaaggtag ataaacattt     3840

tggccattat aatgtgaaac cacttcttct ttctttacag tatttgacca aacttgtgtg     3900

tctatgatat ttgtaaatac atgcgaatat ctgtatttct tatcataagc ctatttagtt     3960

ttattctcag tagggttttt tggattgtac agtgtttata tgatctgaac tccttataca     4020

taagaaggtg tgtatattaa tccaattatg gacttaaaat attttaaaag tataaatacc     4080

cttatttgct gcaaagacca gtgtgtaggc atttgctttt tagcaatatt tttaagtgct     4140

ccattttaat gccgaggaat aagtcttttg gcaacacaaa ctggtcaata ataggtaatg     4200

caggtatgtt caggttaagc caacaatgtt ttgcattttt atgcttattt tctgtcaaca     4260

ctaatgaagt caacattgcc tgaatgtctg aataatgaaa cacatccctg tttaaaagta     4320

tgtaactgaa aaagaaataa aaaaaaataa aagtagtttt tttaaacttg ctctttccca     4380

tttcctctaa agatgggtaa aataatgtca ctccctaatt taagatagga attataaaaa     4440

tttggtttat ttagtctgtt atatatgaga agcagagcta aaggaatatg cttttgttat     4500

tttatgtttt gttttgcttt cttgaaatcc agtggtaaaa agcacacact aggaaggatc     4560

taagctttct ttaatataaa aaaaattata cttctctgaa ctgtttaata gagcaataat     4620

taaatacatc ttctgataaa aaaaaaaaaa a                                    4651


<210>  2328
<211>  4275
<212>  DNA
<213>  homo sapiens

<400>  2328
ctctctatca atatcagctc acatcattga aaagataatt ttgaagacat gttttgctga       60

aaagacacta agaaaaattt tacgaatggg atgaacatgc tccagttaat tgactaccta      120

ctgcaatttg aatgttaaca ttacccatct ggtacagtta cctagtgatg tacctatttt      180

cacaataccc tgtttcagtg tgcttgtctt gattaaagaa ttcaaagtgg agtaccgcaa      240

acttgatatg gaaaataaaa agaaagacaa ggacaaatca gatgatagaa tggcacgacc      300

tagtggtcga tcgggacaca acactcgagg aactgggtct tcatcgtctg gagttttaat      360

ggttggacct aactttagag ttggaaaaaa aattggatgt ggcaattttg gagaattacg      420

attagggaaa aatttataca caaatgaata tgtggcaatt aagttggagc ccatgaaatc      480

aagagcacca cagctacatt tggaatacag attctataag cagttaggat ctggagatgg      540

tatacctcaa gtttactatt tcggcccttg tggtaaatac aatgctatgg tgctggaact      600

gctgggacct agtttggaag acttgtttga cttgtgtgac agaacatttt ctcttaaaac      660

agttctcatg atagctatac aactgatttc tcgcatggaa tatgtccatt caaagaactt      720

gatatacaga gatgtaaaac ctgagaactt cttaatagga cgaccaggaa acaaaaccca      780

gcaagttatt cacattatag attttggttt ggcaaaggaa tatattgatc cggagacaaa      840

gaaacacata ccatacagag aacacaagag ccttacagga acagctagat atatgagcat      900

aaacacacat ttaggaaaag aacaaagtag aagagacgat ttagaagctt taggtcatat      960

gttcatgtat tttctgagag gcagtcttcc ttggcaaggc ttaaaggctg acacattaaa     1020

ggagaggtat cagaaaattg gagatacaaa acgggctaca ccaatagaag tgttatgtga     1080

aaattttcca gaaatggcaa catatcttcg ttatgtaaga aggctagatt tttttgaaaa     1140

accagactat gactacttaa gaaagctttt tactgacttg tttgatcgaa aaggatatat     1200

gtttgattat gaatatgact ggattggtaa acagttgcct actccagtgg gtgcagttca     1260

gcaagatcct gctctgtcat caaacagaga agcacatcaa cacagagata agatgcaaca     1320

atccaaaaac cagtcggcag accacagggc agcttgggac tcccagcagg caaatcccca     1380

ccatttgaga gctcaccttg cagcagacag acatggtggc tcggtacagg ttgtaagttc     1440

tacaaatgga gagttaaaca cagatgaccc caccgcagga cgttcaaatg cacccatcac     1500

agcccctact gaagtagaag tgatggatga aaccaactgc cagaaagtgt tgaacatgtg     1560

gtgctgctgt tttttcaaac gaaggaaaag gaaaaccata cagcgccaca aatgactctg     1620

gacacagaca gatcctgggg agttacttac atgttcatct gctgtcttgt gattaaaatc     1680

atctctgtag tgaccacgta tattttcaag gactcactct tagaaacaaa aatgtcatac     1740

tttcatactt cattttgtgg ttgtcttaca ttctttttct tttttttttt ttctctaatt     1800

taacctttat ggaagcttta aagttttgtc aaaacatgag tgctttgccc atcagtgaat     1860

ggaatggacc aatgaggtgg tatcaatgaa tatagttcca tagaacattt tccagaagtt     1920

cttctgttgt agaaagcagt acagtatctt aagtgtcaac cagttatata cctaatctgg     1980

ttttttataa cttctgtaag agcataatca aacaggaatt ttcttttctc agtggataat     2040

acaacagaga aaacagagtt gcccaaatat ttaaaagaag ttattccttg agaagttcat     2100

attttgtgac atctgcattg atttcagtat tactgatggt actgttattc ataagtcata     2160

ttaacattct ctccgtgaaa tcatggtaca gtcactgccc agaggtactg aggaaaaagc     2220

aatatgggtt cggcagatgg tggtggtaaa atgaatctta aggagtgtgg taaatatgtg     2280

ctccgctttt gttgcatcac tatgtgaagt actgtgttgc agaagtggca aaagcgctta     2340

tttttaaaaa tgcaaaatat ttgtacaatg taactttatg cttccaaata ataatgtatg     2400

ttagacagca agaaatgaat actttaaaaa gtgatgtatg ttggagttat aaagaaatac     2460

actaaggaga ggtagtaaat gtgaaccttg ttgcagtgta taaggtggaa gcctaaagaa     2520

atctcaccga aacttactgc tgaatgatta cattctccct taagcagaaa actttggatg     2580

tgccatgcaa tggtgtctgt gtaattattt tgctctttga ttaaaaaaaa gacccccagc     2640

aataaaaagt gggtcactct atgccctctg tgcacattag tctcttgtat tcaactttgc     2700

tgattctctg gaattttcct actctttagc ataattttga tgattgaaaa atattttgga     2760

aaggatgggt caggtgcttt gcctccatag tcttttgaag tgcctgcata tgaacaacaa     2820

caacaacaac aaaaaattct gtaaaaaagg aagcccattc cacttttcaa gtatgctttg     2880

ttttaagcca taaagacaca catgtagttt tgtcacattc tactagccaa aattttcaag     2940

aagggttaaa acaaagactg gctagaaaga taattatttt gaataaatct catattcatc     3000

tttcatttat ataattgtta cttattcctc ccatgcagtc tcttcgttgt ctttaagtgt     3060

gtgcctccag gcatgcttat ttatttttat tgtctcaagg taacatttaa gatgtatatt     3120

aaagtaaagc tacatttttt tacttcatta ttgcatttac agggatttaa ttgtactttg     3180

taatttattt ttcttattag ccaaaagttt aatgcatttt tttttgatga attaggcacc     3240

cacatgaaca ccacaaatca ggacattgtt tatcattgtt gctatgaatc ctatgaatga     3300

tctttttttt attttaaaga cctacactta acctacaaaa catttgctgt ataatttggt     3360

caacagtttc tatctatctg tatactgtca tgatgtctta aactgcagga gttacatact     3420

gagtttatat ttttatttgc tttgagcaag gtagataaac attttggcca ttataatgtg     3480

aaaccacttc ttctttcttt acagtatttg accaaacttg tgtgtctatg atatttgtaa     3540

atacatgcga atatctgtat ttcttatcat aagcctattt agttttattc tcagtagggt     3600

tttttggatt gtacagtgtt tatatgatct gaactcctta tacataagaa ggtgtgtata     3660

ttaatccaat tatggactta aaatatttta aaagtataaa tacccttatt tgctgcaaag     3720

accagtgtgt aggcatttgc tttttagcaa tatttttaag tgctccattt taatgccgag     3780

gaataagtct tttggcaaca caaactggtc aataataggt aatgcaggta tgttcaggtt     3840

aagccaacaa tgttttgcat ttttatgctt attttctgtc aacactaatg aagtcaacat     3900

tgcctgaatg tctgaataat gaaacacatc cctgtttaaa agtatgtaac tgaaaaagaa     3960

ataaaaaaaa ataaaagtag tttttttaaa cttgctcttt cccatttcct ctaaagatgg     4020

gtaaaataat gtcactccct aatttaagat aggaattata aaaatttggt ttatttagtc     4080

tgttatatat gagaagcaga gctaaaggaa tatgcttttg ttattttatg ttttgttttg     4140

ctttcttgaa atccagtggt aaaaagcaca cactaggaag gatctaagct ttctttaata     4200

taaaaaaaat tatacttctc tgaactgttt aatagagcaa taattaaata catcttctga     4260

taaaaaaaaa aaaaa                                                      4275


<210>  2329
<211>  6103
<212>  DNA
<213>  homo sapiens

<400>  2329
ggcgacggcg gcggccgtcc tcatcccggc gcttgagagg acgcggggct gcgcaaatgg       60

cttgtcccgc tctcggtctg gaagctcttc agcccctgca gcccgagccg ccccccgagc      120

ccgccttctc cgaggcgcag aagtggattg agcaagtaac tggcagaagt tttggtgata      180

aagattttcg gacaggttta gaaaatggaa tcctcctctg cgagttgctg aatgctataa      240

agccaggact tgttaaaaag atcaatagat tgcctacccc cattgcagga ctggacaata      300

ttatcttatt cttgagaggt tgtaaagagc tcggccttaa agaatctcaa ctttttgacc      360

cgagtgacct ccaggataca tccaacagag taacagtcaa gagccttgat tatagtagga      420

agctgaaaaa tgtattagtt accatttact ggctgggaaa agcagcaaac agctgcacat      480

cctacagcgg aacgacacta aacctgaagg agtttgaagg attgttggct cagatgcgaa      540

aggacactga tgacattgaa agtcctaaac gcagtatccg agacagtggc tacatcgact      600

gctgggattc cgagcgcagc gactccctct ctcctcctcg ccacggcaga gatgattcct      660

tcgacagcct ggattccttt ggctctcgct ctcggcagac gccttcacca gatgtagtcc      720

tcaggggaag cagcgatggg agaggaagcg actctgaatc cgacttgcct catcggaagc      780

tgccagatgt gaagaaggat gacatgtctg cacggcggac ttcccatggt gagccgaaat      840

cagcagtgcc ttttaaccag tacctcccga acaaaagcaa tcagacggcc tacgtccccg      900

cgcctctgag aaagaagaaa gcagagagag aggaataccg caagagctgg agtaccgcca      960

cctccccgct gggtggggag aggcccttca gatacggtcc gagaactcct gtgtctgatg     1020

acgcagagag caccagcatg tttgacatgc ggtgtgagga ggaggccgcg gtgcagccgc     1080

acagcagggc ccgccaggag cagctgcagc tgataaataa ccagctgagg gaagaggacg     1140

acaaatggca agatgacctg gctcgttgga agagtcgtag aagaagtgtt tctcaggact     1200

taatcaagaa agaggaagaa aggaaaaaaa tggagaagtt actggctgga gaagatggga     1260

caagtgaacg aaggaaaagc atcaaaacct acagagaaat tgttcaagaa aaagagcgga     1320

gagagagaga gctgcatgaa gcatataaga acgctcggtc ccaggaggag gcagagggga     1380

tccttcaaca gtacattgag aggttcacca tcagtgaggc tgttctcgaa cgcttggaga     1440

tgccaaaaat tctggaaaga agccattcaa cagagccaaa tttatcctcc ttcctgaatg     1500

accccaatcc catgaaatac ctgcggcaac agtcactgcc tccacccaaa ttcactgcca     1560

ctgttgaaac caccattgct cgtgccagtg ttctggatac cagcatgtca gcaggcagtg     1620

ggtctccaag caaaactgtc actcccaaag cagtgcctat gctgacaccc aagccttact     1680

cccagcccaa aaattctcaa gatgttctga agacctttaa ggtagacggg aaagtcagtg     1740

tgaatggaga gacggttcat agagaggagg agaaggaaag agagtgtccc acggtggcac     1800

ctgcccactc cttaaccaaa tcccagatgt ttgaaggtgt ggccagagtg cacgggtctc     1860

cactggagct gaaacaagac aacggtagca tcgagatcaa cataaagaag ccaaactctg     1920

ttccccaaga gctcgcagca accactgaga aaacggaacc gaatagtcaa gaggacaaga     1980

atgatggtgg aaaatcaaga aaagggaata tagaacttgc ctcatcagaa ccacagcatt     2040

ttacaacaac tgtgactcga tgcagcccga ccgtggcctt tgtggaattt ccctccagcc     2100

cccagctgaa gaatgatgtg tcggaagaaa aagaccagaa gaaaccagaa aatgaaatga     2160

gtggaaaggt ggagttggtg ctgtcacaaa aggtggtaaa gccaaaatct ccagaacccg     2220

aagcaacgct gacatttcca tttctggaca aaatgcctga agccaaccaa ctacatttgc     2280

caaatctcaa ttctcaagtg gattctccaa gcagtgagaa gtcacctgtt atgacacctt     2340

ttaagttctg ggcatgggac ccagaagagg agcgcaggcg acaggaaaaa tggcaacagg     2400

aacaggaacg tttgctccag gagagatacc agaaggagca ggacaagctg aaagaagagt     2460

gggaaaaggc ccaaaaggag gtggaagagg aagaacgcag atactatgag gaggagcgta     2520

agataattga agacactgtg gttccattta ctgtttcttc aagttccgct gaccagctgt     2580

ctacctcttc ctccatgact gaaggcagtg ggacaatgaa taagatagac ctgggaaact     2640

gtcaagatga aaaacaagac agaagatgga agaaatcatt ccagggagat gacagtgact     2700

tattgctgaa gactagggaa agtgatcgac tggaggagaa gggcagccta actgaagggg     2760

ccttggctca ttctgggaac cctgtatcaa aaggagtcca tgaagaccat cagctggata     2820

ccgaggctgg ggccccacac tgtggaacaa acccacagct tgctcaggat ccatcccaga     2880

atcagcagac atcaaatcca acgcacagtt cagaagatgt gaagccaaaa accctcccgc     2940

tggataaaag cattaaccat cagatcgagt ctcccagtga aaggcggaag tctataagtg     3000

gaaagaagct gtgctcttcc tgtgggcttc ctttgggtaa aggagctgca atgatcatcg     3060

agaccctcaa tctctatttt cacatccagt gtttcaggtg tggaatttgt aaaggccagc     3120

ttggagatgc agtgagtggg acggatgtta ggattcgaaa tggtctcctg aactgtaatg     3180

attgctacat gcgatccaga agtgccgggc agcctacaac attgtgacac ggctttcaag     3240

cttccggatc actcaccatt tctttactga gagtgtcccc tggcaactgc ttaacaaaat     3300

cccaagctca ggggcttctc agcatttacc taatttctga aaggctcttc tgaaaggtgg     3360

tatctgttct ttcgtagcac agtgtttatg tttttcctgt ttattgtttt ggtttttttt     3420

ttttttttgc atttgcacag tatacacaaa agaatatggg gttgtaatga tcctgaatag     3480

ctcaaaaaag gttttagcat ggtcaaacag gcttatggtt taaaatgtgt tattctcttc     3540

tttgggaatt agctaaatga tgcaataaac ctgttttgtt ttagaatgtc taggaattaa     3600

acactttatg tttacagaat tgagctgcag aaagtgcaag acatgccaat ttgagacaca     3660

cggtcttcta agactgaagg ataaatttaa tgcatttcag aaactaaaca tcacagcaag     3720

ctctatctct gagctataat ttgtttttaa tgcaaagaca ctagtttgat aatatatact     3780

gtaatcctga aacatttgtg ttacttacct ttggaggtag aaattatacc aataaattat     3840

tgcaccgtta gtattagatt ctgtgtacct tggaagttat gtcattaata taggctggtt     3900

catcaaataa agcaaaacct tgcaatatca gctagattta cactccggga cgttgcccaa     3960

aggtaggaag aaagcagagg gaaatatttc agtcatcatt tccaaagtca ttatcaaaat     4020

ctgtgaggaa gtttaatctt ccaaagagtc aatgtcagac atcaggcctc tgttgcctgc     4080

ttctctcgag gcactagatt aggagtcttc aataagagac ttaacatgag gtatatggaa     4140

gatgaggcac cgagataagt tcatcattag gtgtgagcac tgctcaccct tgctggcaag     4200

ttctccttaa gggcctgaag cacaggtgtc caaagaaaag cgttaagtcc atcttaatag     4260

aatctatgtg gtatatgatg tggtcagccc ctggtctgtg atcagcaaga acctacagca     4320

cagattatgc cctgcccact tcaatgaata cctactctcc tccattctcc atcacttttt     4380

ttgctatcaa gaactccgga ccttgcccat ggagaagttt agagaggaac tcttgtggag     4440

agctggttta ttttctgccc tgtgcgacga gtttcagctg gccaagaaag gagtcaagtt     4500

attaaaaagc atcacaatgt agatctccag gctggttttt tgttttttgt tgttaagact     4560

ggggaaaggg ggactattta ttctgcctta aatcaatggc aaataagtca agatgacatt     4620

ttgtgaatgt agactatgga tacactccta atagattgat gtagtcataa aagggggtca     4680

agtagatgtt tttctgttat gtaagcaata atttttccgt gtcttattga gtatggctag     4740

cgattattta ttacatgcta gatgggttct ttgcatgtgg gttccatata ggtgcagaaa     4800

tttcctcagc cactggaggg atttcgacca tatttgtcat ttggatgagc tgttattaga     4860

ttgaaatcta cacatcattt cattaaaaat tgtgccttag aaaacgcaaa gctgttgcac     4920

atggcgataa attatggatg cagtacattg aagagagatg aagtcacttc caagtttcca     4980

agacttctca tggaggtgtt tgctgtttta caggaaaaaa taaaaataaa aaaagaaaaa     5040

aagaaaaaat taaaaagaaa aattgttttg aaaatgtaca gatcaagtcc aatattttga     5100

ttatccacct gcatgtttta ttaaatattt tgataatgtg gatgtttaca ctttgcatga     5160

tattagcaga gtaccactag taatgcacaa acatgtacaa tatggtcatt cataaccgat     5220

ttttatagaa tactttttac atgtgcaact ccatccgtta tgtaaggatt acatgaatat     5280

tgcacattcc cttctggttt cacaaaccca tttatacata tttcttagtg aggctcattg     5340

tacatgtatt gaagctagaa tcgagtcaag aaaaataaag ccccattctc caactgcaaa     5400

atgtgctttc ccataatgaa cactagtcac cagcacagaa taatctccaa cattttctaa     5460

attctaattg ccaactgttt ctatttatat ttgatttata tttcatttgg agtctgttac     5520

atggcagctt aggcagacta gatcttgttt tttccaatgc agcataatga gtatgatcta     5580

tttcttttca aataatcttt gagatcccag gaaaaaaaaa atgctctgct ccattgagct     5640

ataatgtaaa tgtgtttgtt taaaaaacag gtgaggcaag tgagtgattt attgttcctg     5700

aggaagtata tctgattttt tttctcatac tccaaaagct agtccctact ctttaataaa     5760

aataatgggt aactttttgt ttttcactag cgaacttcca tgacatttcc tttctatgta     5820

gtgtgattaa tgcaatacat attatagtta tctatacaca gtgtaagatt taacaaactg     5880

aaatgatcca cctcatatgt gagtccgtcc aaaagatgtt actgctctgg gtgggccagt     5940

gttctatatc ggttatacta actttcattt aaagtattta ttctaaaatg cctctgagaa     6000

acagtaaaaa ataaaaacaa caagttgtct aaaatgcaac agcttttata gtaaatgtac     6060

atttataaat aaaatactca aatcaaaaaa aaaaaaaaaa aaa                       6103


<210>  2330
<211>  2147
<212>  DNA
<213>  homo sapiens

<400>  2330
cacacacaca cacacacaca cacacacaca cacacacaca cacacataca cacgcccggg       60

gaggcaggcc ggagagacct ccctcccgcc cctcccgccc gcctccctcc cctcgccgcc      120

gccgccgccg ccagcatctg ggaccggccg attctgcacc tccgtccggc gctgcccttt      180

gattcggatt tccatcttgc attctccggc tgatcgcggg acctggctcg tgcagaggag      240

gggggccgat cgctatggag tatttcatgg tgcccactca gaaggtgccc tctttgcaac      300

atttcaggaa aacagagaaa gaagtgatag gagggctctg tagccttgcc aacattccac      360

taacccccga gactcagcgg gaccaggagc ggcggattcg gcgggagatc gccaacagca      420

acgagcggag acgcatgcag agcatcaacg cgggattcca gtccctcaag accctcatcc      480

cccacacaga cggagagaag ctcagcaagg cagccattct ccagcagaca gccgagtaca      540

tcttctccct ggagcaggag aagaccaggc tcttgcagca gaacacacag ctcaagcgct      600

tcatccagga gctgagcggc tcgtccccca agcgacggcg ggcagaggac aaggacgaag      660

gcataggctc cccggacatc tgggaggacg agaaggcgga ggacctgcgg cgggagatga      720

ttgagctgcg gcagcagctg gacaaggagc gctcggtgcg catgatgctg gaggagcagg      780

tgcgctcgct ggaggcccac atgtacccgg aaaagctcaa ggtgattgcg cagcaggtgc      840

agctgcagca gcagcaggaa caggtgaggc tgctgcacca ggagaagctg gagcgggaac      900

agcagcagct gcggacccag cttctgcccc ctccggcccc cacccaccac cccacggtga      960

tcgtgccagc accgcctcct cctccctccc accacatcaa tgtcgtcacc atgggcccct     1020

cctcggtcat caactctgtt tccacatccc ggcaaaatct ggacaccatc gtgcaggcaa     1080

tccagcacat cgagggcacc caggaaaagc aggagctgga ggaggagcag cggcgagctg     1140

tcatcgtgaa gcctgtccgc agctgcccgg aggcccccac ctctgacacc gcctccgact     1200

ccgaggcctc agacagtgac gccatggacc agagccggga ggagccgtcg ggggacgggg     1260

agcttccctg actacccccc cagccctcct ctcccttctg ggggctggag ggagccgggg     1320

cagccacagg gagagacatg ggcgaatgag tgagaaattt ttacaaaatt acgatgtcat     1380

ttgggtctct tttatgacct ctttttcaat actgtaaatc gacctttgaa cgaagccact     1440

caacccgagg tcccggggct ggggtgtcgc agagcgtgtg ggagcatcgg caccccaggg     1500

cggggcctcg gccccggggg ctggaggaag ctgacacgga gatgcctggc ctctctctgc     1560

caaaaagcat tttttccttt aaatatgttt tttaagaaca gggaaaatta aacaaaaccc     1620

caggttattt cttccctgcc cagagccagc ctgggattgt cagccttcaa tcccctttcc     1680

ttcctctttt tgggttttct tctttctcct ttaagcactt acatggttgg gggtaagact     1740

aggctggggc attctggggg cccggaggtc tccgttgctt cttggttggg gtttgctgct     1800

gctgtgcccc cctccccctt ccccatctcg gcactagaat tcgccactct cccacccccc     1860

agcccccacc tctgcctcca ggtctcatct tccaccccaa aaatgtctgt ctctctcttt     1920

ttgttttgtt tgttgttggt tttttatttc tttttggttt gctttctgtt tttgttttgt     1980

ttttcttttt tttctttctt tttttttttt ttttacaatt ttgaggtctt cgtgttcaag     2040

gagaagctat tatattttgt taagaaagtg gggagaaaaa aaccaagagg ccaccgtgcc     2100

tttgtaaaga aacaaaataa agtttgtact ttgtttttta aaaaaaa                   2147


<210>  2331
<211>  2896
<212>  DNA
<213>  homo sapiens

<400>  2331
acgcttgcgc gcgggattta aactgcggcg gtttacgcgg cgttaagact tcgtagggtt       60

agcgaaattg aggtttcttg gtattgcgcg tttctcttcc ttgctgactc tccgaatggc      120

catggactcg tcgcttcagg cccgcctgtt tcccggtctc gctatcaaga tccaacgcag      180

taatggttta attcacagtg ccaatgtaag gactgtgaac ttggagaaat cctgtgtttc      240

agtggaatgg gcagaaggag gtgccacaaa gggcaaagag attgattttg atgatgtggc      300

tgcaataaac ccagaactct tacagcttct tcccttacat ccgaaggaca atctgccctt      360

gcaggaaaat gtaacaatcc agaaacaaaa acggagatcc gtcaactcca aaattcctgc      420

tccaaaagaa agtcttcgaa gccgctccac tcgcatgtcc actgtctcag agcttcgcat      480

cacggctcag gagaatgaca tggaggtgga gctgcctgca gctgcaaact cccgcaagca      540

gttttcagtt cctcctgccc ccactaggcc ttcctgccct gcagtggctg aaataccatt      600

gaggatggtc agcgaggaga tggaagagca agtccattcc atccgaggca gctcttctgc      660

aaaccctgtg aactcagttc ggaggaaatc atgtcttgtg aaggaagtgg aaaaaatgaa      720

gaacaagcga gaagagaaga aggcccagaa ctctgaaatg agaatgaaga gagctcagga      780

gtatgacagt agttttccaa actgggaatt tgcccgaatg attaaagaat ttcgggctac      840

tttggaatgt catccactta ctatgactga tcctatcgaa gagcacagaa tatgtgtctg      900

tgttaggaaa cgcccactga ataagcaaga attggccaag aaagaaattg atgtgatttc      960

cattcctagc aagtgtctcc tcttggtaca tgaacccaag ttgaaagtgg acttaacaaa     1020

gtatctggag aaccaagcat tctgctttga ctttgcattt gatgaaacag cttcgaatga     1080

agttgtctac aggttcacag caaggccact ggtacagaca atctttgaag gtggaaaagc     1140

aacttgtttt gcatatggcc agacaggaag tggcaagaca catactatgg gcggagacct     1200

ctctgggaaa gcccagaatg catccaaagg gatctatgcc atggcctccc gggacgtctt     1260

cctcctgaag aatcaaccct gctaccggaa gttgggcctg gaagtctatg tgacattctt     1320

cgagatctac aatgggaagc tgtttgacct gctcaacaag aaggccaagc tgcgcgtgct     1380

ggaggacggc aagcaacagg tgcaagtggt ggggctgcag gagcatctgg ttaactctgc     1440

tgatgatgtc atcaagatga tcgacatggg cagcgcctgc agaacctctg ggcagacatt     1500

tgccaactcc aattcctccc gctcccacgc gtgcttccaa attattcttc gagctaaagg     1560

gagaatgcat ggcaagttct ctttggtaga tctggcaggg aatgagcgag gcgcggacac     1620

ttccagtgct gaccggcaga cccgcatgga gggcgcagaa atcaacaaga gtctcttagc     1680

cctgaaggag tgcatcaggg ccctgggaca gaacaaggct cacaccccgt tccgtgagag     1740

caagctgaca caggtgctga gggactcctt cattggggag aactctagga cttgcatgat     1800

tgccacgatc tcaccaggca taagctcctg tgaatatact ttaaacaccc tgagatatgc     1860

agacagggtc aaggagctga gcccccacag tgggcccagt ggagagcagt tgattcaaat     1920

ggaaacagaa gagatggaag cctgctctaa cggggcgctg attccaggca atttatccaa     1980

ggaagaggag gaactgtctt cccagatgtc cagctttaac gaagccatga ctcagatcag     2040

ggagctggag gagaaggcta tggaagagct caaggagatc atacagcaag gaccagactg     2100

gcttgagctc tctgagatga ccgagcagcc agactatgac ctggagacct ttgtgaacaa     2160

agcggaatct gctctggccc agcaagccaa gcatttctca gccctgcgag atgtcatcaa     2220

ggccttgcgc ctggccatgc agctggaaga gcaggctagc agacaaataa gcagcaagaa     2280

acggccccag tgacgactgc aaataaaaat ctgtttggtt tgacacccag cctcttccct     2340

ggccctcccc agagaacttt gggtacctgg tgggtctagg cagggtctga gctgggacag     2400

gttctggtaa atgccaagta tgggggcatc tgggcccagg gcagctgggg agggggtcag     2460

agtgacatgg gacactcctt ttctgttcct cagttgtcgc cctcacgaga ggaaggagct     2520

cttagttacc cttttgtgtt gcccttcttt ccatcaaggg gaatgttctc agcatagagc     2580

tttctccgca gcatcctgcc tgcgtggact ggctgctaat ggagagctcc ctggggttgt     2640

cctggctctg gggagagaga cggagccttt agtacagcta tctgctggct ctaaaccttc     2700

tacgcctttg ggccgagcac tgaatgtctt gtactttaaa aaaatgtttc tgagacctct     2760

ttctacttta ctgtctccct agagatccta gaggatccct actgttttct gttttatgtg     2820

tttatacatt gtatgtaaca ataaagagaa aaaataaatc agctgtttaa gtgtgtggaa     2880

aaaaaaaaaa aaaaaa                                                     2896


<210>  2332
<211>  4000
<212>  DNA
<213>  homo sapiens

<400>  2332
gcgggcggtc ccggcgaggc gggaggggcc ggggcagagg gagggtcttc gcctccccac       60

ccccagcccc gtttccggag cccgcgatgg agctttgtga agatgcaggc gttggggctg      120

ctcggcgatg atgacatcat cgtgtcacac acaggagccg gctgccgggg ggtttaagag      180

aagagccttt cggaccacac cggcgctcac gctcataccc gcacgccccg ggcagagccg      240

cgcacgccgg ccacactcgg gcgcgcgccg gccacactcg cgcgcacaca tacgcggcgc      300

tcgccccccg gcccccggct cgggccgcga gtcgcagctc cctgccgccg ctcccgccgc      360

cacggatgcc cgcagctgct cccctctgca gtgcagcaac cccggccgcc ggccggctcg      420

ccccggctcc cggctgcagg aatcgcgcca ggacgctggc cccgctcgcg gctagcttgc      480

acgccagggc acagcgagga tgggagggtc gcagtccctg cagccagccc cagccagcga      540

cctgaacctg gaggcttccg aggcaatgag ttccgattct gaagaggcat ttgagacccc      600

ggagtcaacg acccctgtca aagctccgcc agctccaccc ccaccacccc ccgaagtcat      660

cccagaaccc gaggtcagca cacagccacc cccggaagaa ccaggatgtg gttctgagac      720

agtccctgtc cctgatggcc cacggagcga ctcggtggaa ggaagtccct tccgtccccc      780

gtcacactcc ttctctgccg tcttcgatga agacaagccg atagccagca gtgggactta      840

caacttggac tttgacaaca ttgagcttgt ggataccttt cagaccttgg agcctcgtgc      900

ctcagacgct aagaatcagg agggcaaagt gaacacacgg aggaagtcca cggattccgt      960

ccccatctct aagtctacac tgtcccggtc gctcagcctg caagccagtg actttgatgg     1020

tgcttcttcc tcaggcaatc ccgaggccgt ggcccttgcc ccagatgcat atagcacggg     1080

ttccagcagt gcttctagta cccttaagcg aactaaaaaa ccgaggccgc cttccttaaa     1140

aaagaaacag accaccaaga aacccacaga gaccccccca gtgaaggaga cgcaacagga     1200

gccagatgaa gagagccttg tccccagtgg ggagaatcta gcatctgaga cgaaaacgga     1260

atctgccaag acggaaggtc ctagcccagc cttattggag gagacgcccc ttgagcccgc     1320

tgtggggccc aaagctgcct gccctctgga ctcagagagt gcagaagggg ttgtcccccc     1380

ggcttctgga ggtggcagag tgcagaactc accccctgtc gggaggaaaa cgctgcctct     1440

taccacggcc ccggaggcag gggaggtaac cccatcggat agcggggggc aagaggactc     1500

tccagccaaa gggctctccg taaggctgga gtttgactat tctgaggaca agagtagttg     1560

ggacaaccag caggaaaacc cccctcctac caaaaagata ggcaaaaagc cagttgccaa     1620

aatgcccctg aggaggccaa agatgaaaaa gacacccgag aaacttgaca acactcctgc     1680

ctcacctccc agatcccctg ctgaacccaa tgacatcccc attgctaaag gtacttacac     1740

ctttgatatt gacaagtggg atgaccccaa ttttaaccct ttttcttcca cctcaaaaat     1800

gcaggagtct cccaaactgc cccaacaatc atacaacttt gacccagaca cctgtgatga     1860

gtccgttgac ccctttaaga catcctctaa gacccccagc tcaccttcta aatccccagc     1920

ctcctttgag atcccagcca gtgctatgga agccaatgga gtggacgggg atgggctaaa     1980

caagcccgcc aagaagaaga agacgcccct aaagactgac acatttaggg tgaaaaagtc     2040

gccaaaacgg tctcctctct ctgatccacc ttcccaggac cccaccccag ctgctacacc     2100

agaaacacca ccagtgatct ctgcggtggt ccacgccaca gatgaggaaa agctggcggt     2160

caccaaccag aagtggacgt gcatgacagt ggacctagag gctgacaaac aggactaccc     2220

gcagccctcg gacctgtcca cctttgtaaa cgagaccaaa ttcagttcac ccactgagga     2280

gttggattac agaaactcct atgaaattga atatatggag aaaattggct cctccttacc     2340

tcaggacgac gatgccccga agaagcaggc cttgtacctt atgtttgaca cttctcagga     2400

gagccctgtc aagtcatctc ccgtccgcat gtcagagtcc ccgacgccgt gttcagggtc     2460

aagttttgaa gagactgaag cccttgtgaa cactgctgcg aaaaaccagc atcctgtccc     2520

acgaggactg gcccctaacc aagagtcaca cttgcaggtg ccagagaaat cctcccagaa     2580

ggagctggag gccatgggct tgggcacccc ttcagaagcg attgaaatta cagctcccga     2640

gggctccttt gcctctgctg acgccctcct cagcaggcta gctcaccccg tctctctctg     2700

tggtgcactt gactatctgg agcccgactt agcagaaaag aaccccccac tattcgctca     2760

gaaactccag agagaggctg ctcacccaac agacgtctcc atctccaaaa cagccttgta     2820

ctcccgcatc gggaccgctg aggtggagaa acctgcaggc cttctgttcc agcagcccga     2880

cctggactct gccctccaga tcgccagagc agagatcata accaaggaga gagaggtctc     2940

agaatggaaa gataaatatg aagaaagcag gcgggaagtg atggaaatga ggaaaatagt     3000

ggccgagtat gagaagacca tcgctcagat gatagaggac gaacagagag agaagtcagt     3060

ctcccaccag acggtgcagc agctggttct ggagaaggag caagccctgg ccgacctgaa     3120

ctccgtggag aagtctctgg ccgacctctt cagaagatat gagaagatga aggaggtcct     3180

agaaggcttc cgcaagaatg aagaggtgtt gaagagatgt gcgcaggagt acctgtcccg     3240

ggtgaagaag gaggagcaga ggtaccaggc cctgaaggtg cacgcggagg agaaactgga     3300

cagggccaat gctgagattg ctcaggttcg aggcaaggcc cagcaggagc aagccgccca     3360

ccaggccagc ctgcggaagg agcagctgcg agtggacgcc ctggaaagga cgctggagca     3420

gaagaataaa gaaatagaag aactcaccaa gatttgtgac gaactgattg ccaaaatggg     3480

gaaaagctaa ctctgaaccg aatgttttgg acttaactgt tgcgtgcaat atgaccgtcg     3540

gcacactgct gttcctccag ttccatggac aggttctgtt ttcacttttt cgtatgcact     3600

actgtatttc ctttctaaat aaaattgatt tgattgtatg cagtactaag gagactatca     3660

gaatttcttg ctattggttt gcattttcct agtataattc atagcaagtt gacctcagag     3720

ttcctgtatc agggagattg tctgattctc taataaaaga cacattgctg accttggcct     3780

tgccctttgt acacaagttc ccagggtgag cagcttttgg atttaatatg aacatgtaca     3840

gcgtgcatag ggactcttgc cttaaggagt gtaaacttga tctgcatttg ctgatttgtt     3900

tttaaaaaaa caagaaatgc atgtttcaaa taaaattctc tattgtaaat aaaatttttt     3960

ctttggatct tggcaataaa aaaaaaaaaa aaaaaaaaaa                           4000


<210>  2333
<211>  18836
<212>  DNA
<213>  homo sapiens

<400>  2333
agacccgccc gcccgagccg gagttacaag agccgcctcc gcgcacgggg gcccggccac       60

tcggagctgc tctgccgcgg ggactgcacc gcccgccctg ccagacccgc ccggaacggg      120

gctcgtcgcc gccagtagcc gcagcaccgc agccttgggc ctcgcgccgg ctatggccgt      180

gccctggggc tgagccctca ggttgtgacc gagattcccg acgagagaga ctgaggggaa      240

gagaggaagg aggggcgggc tcctggcaag gcattcgctc ctgagcggaa tcctgcaaag      300

atggagaagg aggagacaac ccgggagctg ctgctgccca actggcaggg tagtggctcc      360

cacgggctga ccatcgccca gagggacgac ggcgtctttg tgcaggaggt gacgcagaac      420

tcccctgcgg cccgcactgg ggtggtcaag gagggggacc agattgtggg tgccaccatc      480

tactttgaca acctgcagtc gggtgaggtg acccagctgc tgaacaccat ggggcaccac      540

acggtgggcc tgaagctgca ccgcaagggg gaccgctctc ccgagcctgg ccagacctgg      600

acccgtgaag tcttcagctc ctgcagctct gaagtggttc tgagcgggga tgatgaggag      660

taccagcgca tctacaccac gaagatcaag ccacggctga agtcggaaga tggagtggaa      720

ggagacctcg gggagaccca gagccgtacc atcacagtga ccagaagggt cacggcctac      780

actgtggatg tgactggccg ggaaggagcc aaggacatag acatcagtag ccctgaattc      840

aagatcaaga ttccaagaca tgaactgact gaaatctcca atgtggatgt ggagacccag      900

tctgggaaga ccgtgatcag actgccctcg ggctcggggg cagcctctcc gacaggctct      960

gctgtggata tccgagcagg ggccatttct gcttcaggac cagagctcca aggtgctggc     1020

cactcgaagc tccaggtcac catgcctggg ataaaggtgg gaggctcagg tgtcaatgtc     1080

aatgcaaagg gcttggactt gggtggcaga ggaggggtcc aagttccagc agtggacatt     1140

tcatcttctc ttgggggtag ggcagtagag gtacagggcc catctctgga gagtggtgat     1200

catggcaaaa ttaaatttcc caccatgaaa gtgccgaaat ttggtgtctc aacagggcgt     1260

gagggccaga caccaaaggc agggctgagg gtttctgcac ctgaagtctc tgtggggcac     1320

aagggcggca agccaggctt gactatccaa gcccctcagc tggaagtcag tgtgccctct     1380

gccaatattg agggccttga ggggaagctg aagggccccc aaatcactgg gccatcactt     1440

gagggtgacc taggcctgaa aggtgccaag ccacaggggc acattggggt ggatgcctct     1500

gctccccaaa ttgggggtag catcactggc cccagtgtgg aagttcaggc ccctgacatt     1560

gatgttcagg ggcctgggag caaactgaat gtgcccaaga tgaaagtccc caagttctct     1620

gtatcaggtg caaagggaga ggaaactggg attgatgtga cactgcctac aggtgaagtg     1680

actgttcctg gggtctctgg ggatgtcagc ctgcctgaga ttgctactgg tgggctggaa     1740

ggaaagatga aaggtactaa agtgaagact cctgaaatga ttattcagaa acctaaaatc     1800

tccatgcagg atgtggatct gagccttggg tctcctaaac tgaaaggaga tattaaggtt     1860

tctgctcctg gggtgcaagg tgatgttaaa ggccctcaag tggcacttaa aggctccaga     1920

gtggacatag agacaccaaa cctagaggga accttgacag gccctaggct tggcagtcct     1980

tccgggaaaa ccggaacctg taggatctct atgtcagaag tagacttaaa tgtggccgca     2040

cctaaagtga aagggggtgt agatgtcaca ctccccagag tagaagggaa agtcaaagtc     2100

cctgaagttg atgtcagagg ccccaaagtg gatgtcagtg ccccagatgt cgaagcgcat     2160

ggcccagaat ggaacctgaa aatgcccaag atgaaaatgc ccacgttcag cactccagga     2220

gccaaagggg aaggtccaga tgttcatatg actctaccca aaggagatat cagtatttca     2280

gggcccaagg tcaatgtgga agccccagat gtcaacttgg agggtctggg gggaaaactt     2340

aaaggccccg atgttaagct gcctgatatg agtgtcaaga caccaaagat ctccatgcct     2400

gatgtagatt tgcacgtgaa aggtacaaag gtgaagggag agtatgatgt aactgtacca     2460

aagctggaag gagaactcaa aggcccaaaa gtggacattg atgccccaga tgtggatgtt     2520

catggcccag actggcactt gaagatgccc aagatgaaaa tgcccaaatt cagtgtgcca     2580

gggttcaaag cagagggccc agaagtggat gtgaacctgc ccaaggctga tgtggacatt     2640

tccgggccca agatagatgt tactgctcct gatgtgagca ttgaggaacc agaagggaaa     2700

ttgaaagggc ccaagtttaa gatgcctgag atgaacatca aagtccccaa gatctccatg     2760

cctgatgtgg acttacatct gaaaggccct aacgtaaagg gagaatatga tgtcacaatg     2820

ccaaaggttg aaagtgagat taaagttcct gatgttgaac ttaaaagtgc caaaatggac     2880

attgatgtcc cagatgtgga ggttcaaggc ccagactggc acctgaagat gcccaagatg     2940

aaaatgccca agttcagcat gcctggcttc aaagcagagg gcccagaagt ggatgtgaac     3000

ctgcccaagg ctgatgtgga catctcagga cccaaggtgg gtgttgaagt tccagatgtg     3060

aatattgaag gacctgaagg aaagctgaag ggccccaagt tcaagatgcc agagatgaat     3120

atcaaggccc ccaagatctc catgcctgat gtggacttgc atatgaaagg tcctaaagta     3180

aagggagaat atgatatgac agtgccaaag ctggaagggg acctgaaagg cccaaaagta     3240

gatgtcagtg ccccagatgt tgaaatgcag ggtcctgact ggaacttgaa gatgccaaag     3300

attaaaatgc ccaaatttag catgcccagc ctcaaaggag aggggccaga atttgatgtg     3360

aacctgtcca aagcgaatgt ggacatttct gcaccaaaag tagatactaa tgctccagat     3420

ctgagccttg aaggacctga agggaagttg aaaggcccga agtttaagat gcctgagatg     3480

cacttcagag ctcctaagat gtctttgcca gatgttgacc tggatcttaa aggacccaaa     3540

atgaaaggaa atgtagatat ctctgcacca aagatagagg gtgaaatgca ggttccagat     3600

gtggacatca gaggtcccaa ggtagatatt aaagcaccag atgtggaagg ccaaggcctg     3660

gactggagcc tgaaaatacc caagatgaaa atgcccaagt tcagcatgcc cagcctcaaa     3720

ggcgagggcc cagaagtgga tgtgaacttg cctaaggctg acgttgttgt ctcaggaccc     3780

aaggtggaca tcgaagcccc agatgtgagc ctcgaaggtc cagaagggaa gctgaagggt     3840

cccaagttta agatgcctga gatgcatttc aagaccccca agatctccat gcctgatgtg     3900

gacttacact tgaaaggccc caaagtcaaa ggggatgtgg atgtgtctgt gcccaaggta     3960

gaaggtgaaa tgaaagtgcc agatgttgaa atcaaaggac ccaaaatgga cattgatgcc     4020

ccagatgtgg aggttcaagg cccagactgg cacctgaaga tgcccaagat gaaaatgccc     4080

aagtttagca tgcctggctt caaaggagag ggccgagaag tggatgtgaa cctgcccaag     4140

gctgacattg atgtctcagg acccaaggtg gatgttgaag tcccagatgt gagccttgag     4200

ggcccggaag gaaagctgaa gggccccaag tttaagatgc ctgagatgca cttcaaggcc     4260

cccaagatct ccatgcctga tgtggacctg aatcttaagg ggccaaaatt gaagggagat     4320

gtggatgtgt ccttgcctga ggtagaaggt gaaatgaaag tgccagatgt tgacattaaa     4380

gggcccaaag ttgacattag tgctccagat gtggatgttc atggcccaga ttggcacctg     4440

aagatgccca aggtgaaaat gcccaagttc agcatgcccg gcttcaaagg agagggccct     4500

gaagtggatg tgaagctgcc caaagctgac gttgatgtct caggacccaa aatggatgct     4560

gaagttccag atgtgaatat tgaaggtcca gacgcaaaac taaaaggtcc caaattcaag     4620

atgccagaaa tgagtataaa gcctcagaag atatccatac cagatgttgg tttgcatttg     4680

aaaggtccta aaatgaaagg agattatgat gtaacagttc caaaagtaga aggagagata     4740

aaagctcctg atgttgacat caaaggcccc aaagttgata ttaatgcacc agatgtggag     4800

gttcatggcc cagactggca cctgaagatg cccaaggtaa aaatgcccaa gttcagcatg     4860

cctggcttta aaggagaggg cccagaggtg gatatgaacc tgcccaaggc tgaccttggt     4920

gtttcaggac ccaaggtgga cattgatgtt ccagatgtga atcttgaagc tccagagggg     4980

aaactaaaag gccctaagtt caagatgcca agcatgaata tacagacgca caaaatctct     5040

atgcctgatg ttggacttaa tttgaaagcc cctaaactga aaactgatgt agatgtttcc     5100

cttcccaaag tggaaggaga cttgaagggt cctgaaattg atgtgaaagc ccctaagatg     5160

gatgtgaatg ttggtgatat tgatattgaa ggtccagaag ggaagttgaa gggccccaag     5220

tttaagatgc ctgagatgca tttcaaggcc cccaagatct ccatgcccga tgtggactta     5280

cacttgaaag gccccaaagt caaaggggat atggatgtgt ctgtgcccaa ggtagaaggt     5340

gaaatgaaag tgccagatgt tgacattaaa gggcccaaag tggacattga tgccccagat     5400

gtggaggttc acgacccaga ttggcacctg aaaatgccca agatgaaaat gcccaagttc     5460

agtatgcctg gcttcaaagc agagggccct gaagtggatg tgaatctgcc aaaggctgac     5520

attgatgtgt ctggacccag tgtggacact gatgctcctg atttggatat tgagggacca     5580

gaaggaaagt tgaaaggctc caaatttaag atgcccaagt tgaatataaa agctcccaag     5640

gtctccatgc cagatgtgga cttgaatttg aagggaccca aactgaaggg agagatagat     5700

gcttctgtgc cagaactgga aggtgatctc agagggccgc aagttgatgt caaaggtcct     5760

tttgtggaag cggaggtgcc cgatgttgat ctggagtgtc ctgatgcaaa gttgaaaggg     5820

cccaagttta agatgcctga gatgcacttc aaggccccca agatctccat gcctgatgtg     5880

gacttacacc tgaaaggccc caaagtcaaa ggggatgcgg atgtgtcggt gccaaaattg     5940

gagggagatt taacaggccc cagtgtgggt gtggaggtgc ctgatgttga gctggagtgt     6000

cctgatgcaa agttgaaagg ccctaaattt aagatgccag acatgcactt caaggccccc     6060

aagatctcca tgcctgatgt ggacttacac ttgaaaggcc ccaaagtcaa aggggatgtg     6120

gatgtgtcgg tgccaaaatt ggagggagat ttaacaggtc ccagtgtggg tgtggaggtg     6180

cctgatgttg agctggagtg tcctgatgca aagttgaaag ggcccaagtt taagatgcct     6240

gagatgcact tcaagacccc caagatctcc atgcctgatg tggacttaca cctgaaaggc     6300

cccaaagtca aaggggatat ggatgtgtct gtgcccaagg tagaaggtga aatgaaagtg     6360

ccagatgttg acatcaaagg acccaaaatg gacattgatg ccccagatgt ggatgttcat     6420

ggcccagact ggcacctgaa gatgcccaag atgaaaatgc ccaagttcag catgcctggc     6480

ttcaaagcag agggcccaga agtggatgtg aacttgccca aggctgatgt tgttgtctca     6540

ggacccaagg tggatgttga agtcccagat gtgagccttg aaggtccaga agggaagctg     6600

aagggcccca agcttaagat gcctgagatg cacttcaagg cccccaagat ctccatgcct     6660

gatgtggact tacacttgaa aggccccaaa gtcaaagggg atgtggatgt gtctttgcca     6720

aaattggagg gagatttaac aggccccagt gtggatgtgg aggtgcctga tgttgagctg     6780

gagtgtcctg atgcaaagtt gaaagggccc aagtttaaga tgcctgagat gcacttcaag     6840

acccccaaga tctccatgcc tgatgtgaac ttaaacttga aaggccccaa agtcaaaggg     6900

gatatggatg tgtctgttcc caaggtagaa ggtgaaatga aagtgccaga tgttgacatc     6960

agagggccca aagtggacat tgatgcccca gatgtggatg ttcatggccc agactggcac     7020

ctgaagatgc ctaagatgaa aatgcccaag ttcagcatgc ctggcttcaa aggagagggc     7080

ccagaagtgg atgtgaactt gcccaaggct gacgttgatg tctcaggacc caaggtggat     7140

gttgaagtcc cagatgtgag ccttgaaggt ccagaaggga agctgaaggg ccccaagttt     7200

aagatgcctg agatgcactt caagaccccc aagatctcca tgcctgatgt tgatttcaat     7260

ttaaagggac ccaaaatcaa aggagatgtt gatgtttctg ccccaaagct ggagggagag     7320

ttaaaaggtc cagaattgga tgtcaaaggt cccaaattag atgctgacat gccagaagta     7380

gctgtggaag gcccaaatgg caagtggaaa actcctaagt tcaagatgcc agatatgcac     7440

tttaaagctc ccaaaatctc tatgccagac ctcgatctac acttgaagag ccccaaggca     7500

aaaggagagg tggatgtaga tgttcccaaa ttggaagggg accttaaagg gccacatgtg     7560

gatgtcagtg ggccagacat tgacattgag ggaccagagg gcaaattgaa aggccctaag     7620

ttcaagatgc ctgatatgca tttcaaagcc cccaatattt ctatgcctga tgttgatcta     7680

aatctcaaag gacccaaaat caagggggat gtggatgtgt ctgtgcctga ggtagaaggt     7740

aaacttgaag taccagatat gaacatcagg ggccccaaag ttgatgtaaa tgcccccgat     7800

gtccaagctc cagactggca cctgaagatg cccaagatga aaatgcccaa gttcagcatg     7860

cctggcttca aagcagaggg ccctgaagta gacgtcaact tgcctaaggc tgacgttgac     7920

atctcaggac ccaaggtgga cattgaaggc cctgatgtta atattgaagg accagaggga     7980

aagttgaaag ggcctaagtt aaagatgcca gagatgaaca tcaaagcccc caagatctcc     8040

atgcctgact ttgatttgca tctgaaaggt cccaaggtga agggcgatgt ggatgtttct     8100

ctgcccaaag tggaaggtga cctcaagggc cccgaagttg acatcaaggg gcccaaagtg     8160

gatattaatg ccccagatgt gggtgttcaa ggcccagact ggcacctgaa gatgcccaag     8220

gtgaaaatgc caaagttcag catgcctggc ttcaaaggag agggcccaga tggggatgtg     8280

aagctgccca aggctgacat tgatgtctca ggacccaaag tggacattga aggccctgat     8340

gttaacattg aaggaccaga gggaaagttg aaagggccta agttcaagat gccagagatg     8400

aatatcaaag cccccaagat ctccatgcct gatattgact taaacctgaa aggacccaaa     8460

gtgaagggtg atgtggatgt ttcccttcct aaagtggaag gtgacctcaa gggcccagaa     8520

gttgacatca agggcccaaa agtggacatt gacgcacctg atgttgatgt tcatggccca     8580

gactggcacc taaagatgcc caagataaaa atgcccaaga tcagcatgcc tggcttcaaa     8640

ggagaaggtc cagatgtgga cgtgaacctg cccaaggctg acattgatgt ctcaggaccg     8700

aaagtggatg ttgaatgtcc cgatgtgaat atcgaaggac ctgaaggaaa gtggaaaagt     8760

ccaaagttta agatgccaga gatgcatttt aagactccaa agatatccat gccagatatt     8820

gacctgaatc tcacaggtcc aaaaataaaa ggagatgtgg atgttacagg ccctaaggta     8880

gagggagatc tgaaaggtcc tgaagttgac ctcaaaggcc ccaaagtgga cattgatgtc     8940

ccagatgtta atgttcaggg tccagactgg cacctgaaga tgcccaagat gaaaatgccc     9000

aagttcagca tgcctggctt caaagcagag ggccctgaag tggatgtgaa cctgcccaag     9060

gctgacgttg atgtctcagg ccccaaagtg gacgttgaag gccctgatgt taacattgaa     9120

ggaccagagg gaaagttgaa agggcccaag ttcaagatgc cagagatgaa tatcaaagcc     9180

cccaagatcc ccatgcctga ctttgatttg catctgaaag gtcccaaggt gaagggcgat     9240

gtggatattt ctctgcccaa agtggaaggt gacctcaagg gccctgaagt tgacatcagg     9300

ggtccccaag tggacattga tgtcccggat gtgggcgttc aaggcccaga ctggcaccta     9360

aaaatgccca aagtgaaaat gcccaaattc agcatgcctg gcttcaaagg agagggccca     9420

gatgtggatg tgaacctgcc caaggctgac cttgatgtct caggacccaa ggtggacatt     9480

gatgttccag atgtgaatat cgaaggccca gagggaaagt tgaaaggtcc caaattcaaa     9540

atgcctgaga tgaacatcaa agcccccaag atctccatgc ctgacattga tcttaacctg     9600

aaaggtccca aagtgaaggg tgacatggat gtgtctctgc caaaagtgga aggtgacatg     9660

aaagttcctg acgtggatat taaaggcccc aaagtggata ttaatgcccc agatgtggat     9720

gttcaaggcc cagactggca cctgaagatg cctaaaataa aaatgcccaa gatcagcatg     9780

cctggcttca aaggagaagg tccagaagtg gacgtgaacc tgcccaaggc tgaccttgac     9840

gtctcaggac ccaaggtgga cgttgatgtt ccagatgtga atattgaagg tccagatgcg     9900

aaactgaagg gccctaaatt caagatgcca gagatgaaca tcaaagctcc taaaatatca     9960

atgcctgatt tggacctcaa tcttaaaggc cctaaaatga aaggagaggt ggatgtttca    10020

cttgcaaatg tagaaggtga tttgaaagga cctgctcttg acataaaagg cccaaagata    10080

gatgtagatg ctccagatat tgacattcat ggcccagatg ccaaattaaa aggtccaaaa    10140

ctgaagatgc ctgacatgca tgtaaacatg cccaagatct ccatgccaga aattgacttg    10200

aatttgaaag gctcaaagct taagggagat gttgatgtct ctgggcccaa gttggaaggt    10260

gacattaaag ctcccagttt ggatataaag ggcccagaag tggacgtttc cggtcctaag    10320

cttaatatcg aaggcaagtc aaagaaatct cgttttaagc ttcccaaatt taatttttcg    10380

ggctctaaag ttcagacacc tgaagtggat gtcaaaggta aaaagccaga tattgacata    10440

acaggtccaa aagttgatat taatgctcct gatgtcgagg tccaaggaaa agtgaaagga    10500

tccaagttta aaatgccttt cctgagtatt tcatctccca aagtttctat gcctgacgtg    10560

gagctaaatt tgaaaagtcc caaagtcaaa ggagacttag atattgcagg tcccaattta    10620

gaaggtgact ttaaaggccc caaagtggat attaaggcac cagaagtcaa tcttaatgca    10680

cctgatgtgg atgttcatgg tccagactgg aatctgaaaa tgcccaagat gaaaatgccc    10740

aaattcagtg tgtctggctt aaaagcagaa gggccagatg tagctgtgga tctaccaaaa    10800

ggagacatca acatagaggg cccaagtatg aacattgagg gcccagatct caatgtggaa    10860

ggtccggagg gaggcttgaa aggtcccaaa ttcaagatgc ctgacatgaa tatcaaagct    10920

cccaagatct ccatgcctga cattgactta aacttgaaag gccccaaggt gaaaggtgat    10980

gtggatattt ctcttcccaa acttgaaggg gatctgaaag ggccagaggt tgatatcaaa    11040

ggccctaaag tggacatcaa tgccccagat gtggatgttc atggtccaga ctggcatctg    11100

aagatgccca aagtgaaaat gcccaagttc agcatgcctg gcttcaaagg agaaggccct    11160

gaagtcgatg ttaccctccc taaagctgac attgacattt ctggtcccaa tgtagacgtt    11220

gatgttccag acgtgaatat tgaaggtcca gatgcaaagc tgaagggccc caagttcaag    11280

atgcctgaga tgaacatcaa agcccccaag atctccatgc ctgactttga cctgaacttg    11340

aagggaccca aaatgaaggg tgatgtggtt gtgtctttgc ccaaagtgga aggtgatcta    11400

aaaggccctg aggtggacat caagggcccc aaagtggaca ttgacactcc tgacattaac    11460

atcgaaggct cagagggtaa attcaaggga cccaaattta agataccaga gatgcacctg    11520

aaggctccca aaatatcgat gcctgacatt gatttaaacc tgaagggccc caaagtcaag    11580

ggcgatgtgg atgtttctct gcccaaaatg gaaggtgacc tcaagggtcc tgaagttgac    11640

atcaagggcc ccaaagtgga cattaatgct ccagatgttg atgttcaagg cccagactgg    11700

cacctgaaga tgcccaaggt gaaaatgccc aagttcagca tgcctggctt caaaggagag    11760

ggcccagatg tggatgtgaa cctgcccaag gctgaccttg atgtctcagg acccaaggtg    11820

gacattgatg ttccagatgt gaatatcgaa ggcccagagg gaaagttgaa aggtcccaaa    11880

ttcaagatgc ctgagatgaa catcaaagcc cccaagatct ccatgcctga cattgatctt    11940

aacctgaaag gacccaaagt gaagggtgat atggatgtgt ctctgccaaa agtggaaggt    12000

gacatgcaag ttcctgactt ggatattaaa ggccccaaag tggatattaa tgccccagat    12060

gtggatgttc gaggcccaga ctggcacctg aagatgccta agataaaaat gcccaagatc    12120

agcatgcctg gcttcaaagg agaaggtcca gaagtggatg tgaacctgcc caaggctgac    12180

cttgacgtct caggacccaa ggtggacgtt gatgttccag atgtgaatat tgaaggtcca    12240

gatgcgaaac tgaagggccc taaattcaag atgccagaga tgaacatcaa agcccccaag    12300

atctccatgc ctgactttga tttgcatctg aaaggcccta aggtgaaagg agatgtggat    12360

gtttctctgc ctaagatgga aggtgatcta aaggcccctg aagttgacat caagggcccc    12420

aaagtggaca ttgatgcccc agatgtggat gttcatggcc cagactggca cctgaagatg    12480

cccaaggtga aaatgcccaa attcagcatg ccaggattta aaggagaggg cccagaagtg    12540

gatgttaatt tgcccaaagc tgacattgat gtctcaggac ccaaagtgga cattgacact    12600

cctgatattg atattcatgg tccagaaggg aaactgaagg gccccaaatt taaaatgcct    12660

gacctgcacc tcaaggcacc gaagatctct atgcctgaag ttgacctgaa tctgaaaggt    12720

ccaaagatga agggcgacgt ggacgtttct ctgcccaaag tggaaggcga cctcaagggc    12780

cctgaagttg acatcaaggg ccccaaagtg gacattgatg tcccagatgt ggacgttcaa    12840

ggcccagact ggcacttaaa aatgcccaaa gtgaaaatgc ccaagttcag catgcctggc    12900

ttcaaaggag agggcccaga tgtggatgtg aacctgccca aggctgacct tgacgtctca    12960

ggacccaagg tggacattga tgttcctgat gtgaatatcg aaggtccaga tgcgaaacta    13020

aagggcccta aattcaagat gcctgagatg aacatcaaag cccccaagat ctccatgcct    13080

gactttgatt tgcatctgaa aggtcccaag gtgaagggtg atgtggatgt ttcccttcct    13140

aaagtggaag gtgacctcaa gggcccagaa gttgacatca agggccccaa agtggacatc    13200

gatgcccctg atgtagatgt tcatggccca gactggcacc tgaagatgcc caaggtgaaa    13260

atgcccaaat tcagcatgcc aggattcaaa ggagagggcc cagatgtgga tgttaccctt    13320

cctaaggctg acattgagat ttctggcccc aaagtggaca ttgatgcccc tgatgtcagt    13380

atcgaaggtc cagatgcaaa actcaagggt ccaaagttca agatgccaga gatgaacatc    13440

aaggccccca aaatctccat gcctgacatt gactttaact tgaagggtcc caaagtgaaa    13500

ggtgatgtgg atgtctctct gcccaaagtg gaaggtgatc tcaagggccc tgaaattgac    13560

ataaaaggcc ccagtttgga cattgacaca cctgatgtca atattgaagg tccggaagga    13620

aaattgaagg ggcccaaatt taagatgcct gagatgaaca tcaaagctcc caaaatctct    13680

atgcctgact ttgatttgca cctgaaaggt cccaaggtga agggtgatgt ggatgtttca    13740

ctacctaagg tggaaagtga tctgaaaggg ccagaggtag acattgaagg tcctgaaggg    13800

aagctcaaag gtcccaagtt taagatgcct gatgtacatt tcaaaagccc acaaatctcc    13860

atgagtgaca ttgatttgaa tttgaaagga cctaagataa aaggagatat ggacatttcc    13920

gttcctaaac tggagggaga tctgaaaggt cccaaagtgg atgtcaaagg ccctaaagtg    13980

ggcattgaca ctcctgatat tgacattcat ggtccagaag ggaaactgaa gggccccaaa    14040

tttaaaatgc ctgacttaca cctcaaggca ccgaagatct ctatgcctga agttgacctg    14100

aatctgaaag gtccaaaggt gaagggcgac atggacattt ctctgcccaa agtggaaggc    14160

gacctcaagg gccccgaagt tgacatcagg gaccccaaag tggacattga tgtcccagat    14220

gtggacgttc aaggcccaga ctggcaccta aaaatgccca aagtgaaaat gcccaagttc    14280

agcatgcctg gcttcaaagg agagggccca gatgtggatg tgaacctgcc caaggctgac    14340

attgatgtct caggacccaa agtggacgtt gatgttcctg atgtgaatat cgaaggtcca    14400

gatgcgaaac taaagggccc caagttcaag atgcctgaga tgagcatcaa agcccccaag    14460

atctccatgc ctgatattga cttaaacctg aaaggaccca aagtgaaggg cgatgtggat    14520

gttacccttc ctaaagtgga aggtgacctc aagggcccag aagctgacat caagggccca    14580

aaagtggaca tcaacacccc tgatgtggat gttcatggcc cagactggca cctgaagatg    14640

cccaaggtga aaatgcccaa attcagcatg cctggcttca aaggagaagg tccagatgtg    14700

gatgtgagcc tgcccaaggc cgacatcgat gtctcgggac ccaaggtgga cgttgatatt    14760

ccagatgtga atatcgaagg tccagacgca aaactgaagg gccccaagtt caagatgcct    14820

gaaataaata tcaaagctcc caagatctcc atacctgatg ttgacctgga tttgaaagga    14880

cccaaagtaa aaggagattt tgatgtgtct gtccctaagg ttgaagggac tttgaaaggc    14940

ccagaagtag atcttaaagg tccacgtctg gatttcgaag gccctgatgc caaactcagt    15000

ggcccatctt tgaagatgcc atcgctggag atatctgctc ctaaagtaac tgctcctgat    15060

gttgatttgc atctcaaggc accaaaaatt ggattttcag gtccgaagtt agaaggtggt    15120

gaagtggacc tcaagggacc caaagttgaa gctccaagct tagatgtaca catggacagc    15180

ccagatatta acatcgaagg gccagatgtt aaaatcccca aatttaagaa acccaagttt    15240

ggatttgggg caaaaagccc caaagctgac atcaagtcac cttcactgga tgtcactgtt    15300

cctgaggcag agctgaacct tgagactcct gaaattagtg ttggtggcaa gggcaagaaa    15360

agtaagttta aaatgcctaa aattcatatg agtggtccta agattaaggc caaaaaacag    15420

ggatttgacc tgaatgttcc tgggggtgaa attgatgcca gcctcaaggc tccggatgta    15480

gatgtcaaca tcgcagggcc ggatgctgca ctcaaagtcg acgtgaaatc gcccaaaacc    15540

aagaaaacga tgtttggaaa aatgtacttc ccagatgtag agtttgacat taaatcacct    15600

aaatttaaag ctgaggcccc tctccctagc cccaaactgg agggtgaact ccaggcacct    15660

gatctggaac tttctttgcc agcgattcac gtcgaaggtc ttgacatcaa ggcgaaggct    15720

cccaaggtca agatgccaga tgtggacatc tcagtgccaa aaatagaggg tgacctgaaa    15780

ggccccaaag tgcaggcaaa cttgggtgca cctgacatca acatcgaagg cctagatgct    15840

aaagtcaaaa caccgtcctt cggcatttct gcccctcaag tctccatccc tgatgtgaat    15900

gtaaacttga aaggaccaaa gataaagggt gatgtcccca gcgtgggact ggaaggacca    15960

gatgtagatc tgcaaggtcc agaagcaaaa attaagttcc ccaagttttc catgcccaag    16020

atcggcatcc caggtgtgaa aatggagggt gggggagccg aggtccatgc ccagctaccc    16080

tctcttgaag gagacttgag aggaccagat gttaagctcg aagggcccga tgtttctcta    16140

aaggggccag gagtagactt gccttcagtg aacctctcta tgccaaaagt ctctgggcct    16200

gaccttgatc tgaacttgaa aggaccaagt ttgaagggag acctggatgc atctgttccc    16260

agcatgaagg tgcatgctcc agggctcaac ctcagtggtg tcggtggcaa aatgcaggtg    16320

ggaggagacg gtgtgaaagt gccagggatc gatgccacaa caaagcttaa cgttggggca    16380

ccagatgtga cactgagggg accaagcctg cagggagatc tggctgtctc tggtgacatc    16440

aaatgcccta aagtatccgt aggagctcct gatctaagct tggaggcatc cgaaggcagc    16500

attaaacttc ccaaaatgaa gctgccccaa tttggcatct ctactccggg gtccgacttg    16560

cacgtcaatg ccaaggggcc acaggtttct ggcgaactga aggggccagg tgtggatgtg    16620

aacctgaaag ggcctcggat ttcagcaccg aatgtggact ttaacttgga aggaccaaaa    16680

gtgaaaggga gccttggggc cactggtgag atcaaaggcc ccactgtcgg aggaggtctt    16740

ccaggcattg gtgttcaagg cctagaagga aacctccaga tgcctggaat taagtcctct    16800

ggatgtgatg tgaacctgcc aggcgtgaat gtgaaactcc caactgggca gatttctggg    16860

cctgaaatca aaggtggtct gaaaggttca gaagtaggtt tccatggggc tgctcctgat    16920

atcagtgtga aggggcctgc ctttaatatg gcatctcctg agtcagattt tggcatcaac    16980

ttgaagggcc caaaaatcaa aggaggtgcg gatgtttcag ggggtgtcag tgccccagac    17040

atcagccttg gtgaagggca tttgagtgtt aaaggttccg ggggtgagtg gaagggaccc    17100

caagtctcct ctgctctcaa cttggacaca tctaagtttg ctgggggcct tcatttctca    17160

ggaccaaagg tggaaggagg tgtgaaagga ggtcagattg gactccaggc tcctgggctg    17220

agtgtgtctg ggcctcaagg tcacttggaa agtggatctg gaaaagtaac attccctaaa    17280

atgaagatcc ccaaatttac cttctctggc cgtgagctgg ttggcagaga aatgggggtg    17340

gatgttcact tccctaaagc agaggccagc atccaagctg gtgctggaga cggcgagtgg    17400

gaagagtctg aagtcaaact gaaaaagtcc aagatcaaaa tgcccaagtt taatttttcc    17460

aaacctaaag ggaaaggtgg tgtcactggc tcaccagaag catcaatttc tgggtccaaa    17520

ggtgacctga aaagttcaaa ggccagcctg ggctctctgg aaggagaggc agaggccgaa    17580

gcctcttcac cgaaaggcaa attctcctta tttaaaagta agaagccacg gcaccgctca    17640

aattcattca gtgatgaaag agagttctct ggaccttcca ccccgacggg gacgctggag    17700

tttgaaggtg gggaagtgtc tctggaaggt gggaaagtta aagggaaaca cgggaagctg    17760

aaattcggta cctttggtgg attggggtca aagagcaaag gtcattatga ggtgactggg    17820

agcgatgatg agacaggcaa gttacagggg agtggggtgt ccctggcctc taagaagtcc    17880

cgactgtcct cctcttctag caatgacagt gggaataagg ttggcatcca gcttcccgag    17940

gtggagctgt cagtttccac aaagaaagag tagcaggcct ttgtatgtgt gtacatatat    18000

atatatataa caaaacatca gccttgggtg gtgtgttcct atataaactc caaagggaaa    18060

cacaccgact gcctcagcaa tcatgcaaag accttgcctg gcccggtggc aagcgctgaa    18120

aaaccgaccg cctgtaggct cctggaacta tacagatagg taaagagttc caagttcgtc    18180

cagcccatgt gcaaagtcaa cagtatttgc cttaagattt catatatata tatttttttg    18240

cattgactgc tgagagctcc tgtttactaa gcaagctttt gtgtttatta tcctcatttt    18300

tactgaacat tgttagtttt ggggtaatgg aaacccactt tttcattgta atgactttgg    18360

gggcttttgt tagtaagggt gggtggggtg atgggttgca gacggaggtc aggtcttcct    18420

ctttcctgag actggatctg ttcaaacagc aaacgcccac agatggccca gaggtggtgg    18480

tagtcagggt gtgtgggtgt ttttagggtt ctttagtgtt gtttctttca cccaggggtg    18540

gtggtcccag ccagtttggt gctgacggtg agaggaaatt agaatctgtt tgcaaattgt    18600

ccaacccacc ccctcaacat gaggggcttc cattttctgt gttttgtaag ggaactgttt    18660

ccttcatgcc gccatgttcc tgatattagt tctgatttct ttttaacaaa tgttatcatg    18720

attaagaaaa tttccagcac tttaatggcc aattaactga gaatgtaaga aaattgatgc    18780

tgtacaaggc aaataaagct gtttattaac cttgaaaaaa aaaaaaaaaa aaaaaa        18836


<210>  2334
<211>  2875
<212>  DNA
<213>  homo sapiens

<400>  2334
attcgcctcc atggcccact cgccggtggc tgtccaagtg cctgggatgc agaataacat       60

agctgatcca gaagaactgt tcacaaaatt agagcgcatt gggaaaggct catttgggga      120

agttttcaaa ggaattgata accgtaccca gcaagtcgtt gctattaaaa tcatagacct      180

tgaggaagcc gaagatgaaa tagaagacat tcagcaagaa ataactgtct tgagtcaatg      240

tgacagctca tatgtaacaa aatactatgg gtcatattta aaggggtcta aattatggat      300

aataatggaa tacctgggcg gtggttcagc actggatctt cttcgagctg gtccatttga      360

tgagttccag attgctacca tgctaaagga aattttaaaa ggtctggact atctgcattc      420

agaaaagaaa attcaccgag acataaaagc tgccaatgtc ttgctctcag aacaaggaga      480

tgttaaactt gctgattttg gagttgctgg tcagctgaca gatacacaga ttaaaagaaa      540

tacctttgtg ggaactccat tttggatggc tcctgaagtt attcaacagt cagcttatga      600

ctcaaaacgt cctacagcaa aagaacttct gaaacacaaa ttcattgtaa aaaattcaaa      660

gaagacttct tatctgactg aactgataga tcgttttaag agatggaagg cagaaggaca      720

cagtgatgat gaatctgatt ccgagggctc tgattcggaa tctaccagca gggaaaacaa      780

tactcatcct gaatggagct ttaccaccgt acgaaagaag cctgatccaa agaaagtaca      840

gaatggggca gagcaagatc ttgtgcaaac cctgagttgt ttgtctatga taatcacacc      900

tgcatttgct gaacttaaac agcaggacga gaataacgct agcaggaatc aggcgattga      960

agaactcgag aaaagtattg ctgtggctga agccgcctgt cccggcatca cagataaaat     1020

ggtgaagaaa ctaattgaaa aatttcaaaa gtgttcagca gacgaatccc cctaagaaac     1080

ttattattgg cttctgtttc atatggaccc agagagcccc accaaaccta cgtcaagatt     1140

aacaatgctt aacccatgag ctccatgtgc cttttggatc tttgcaacac tgaagatttg     1200

gaagaagcta ttaaactatt ttgtgatggc gtttatcatt ttatattttg aaaggattat     1260

tttgtaagga ataactttta atactatagt ttcacctgta ttctagtaaa tgttgagaca     1320

ccgttttgct tttaagtatc cctatttctt aagttacgag gatgaatacc tttcacattt     1380

tgatctttag ttgactctac agtcatgaaa catacaggtc tttcaaagtc attctcaata     1440

ttcagctttt gtaaattatc aagcttcaaa aagctttttt ttttaaaaaa aaacatgcat     1500

attctaaaaa tgactattgg tggggaggtg taaataagtc ataccttctt aaaacagaaa     1560

atttaagtaa agtcttttaa atgaaacctg taaaagtatt gactcttcta ccaagttggt     1620

atgatattcc aggcagctca atgattatca catttgagac cctgtgtttg aagcatttac     1680

aggcaatgta cagcaacaga ggtacctctt ggtgtatagt atttacattc tcttttaggt     1740

agaagaggca attttaccct tatttcacat ggttagaaat ttaaagcaag atcatttacc     1800

caaggatagg tgtttggtaa tgttgaagga gttagtctgg cttcatgttt tacatcttca     1860

actaaaatcc catactatct gcttggattt ggagagccaa aaaataaagc tgattgtcat     1920

gtgattaaat atctgatcaa caggtatgaa tataacttaa atcagcatat ttttgccatg     1980

gtaataaatt gtcctataaa ctatttatat atttttgttc ttcataatta tcactaataa     2040

gcatcagttt gttgttttta aaaggatatt taagtgagca ttttctagtt catatgaaaa     2100

taaccatagt acaggatgat ttctgtccac acaaaggtta aattagattg cacagttaat     2160

tttcacttat atttatggta ctattatgtg ggtgatgcct ttttctttta agcccagtac     2220

atatattatg cctgcctaag ttctgaactg gggctgtatt tcagtagttg tagaattatt     2280

gatatttagt tttgatagct aatgtttaat tgtttggatc tgcacagttt ggtttttgca     2340

caaaagtcat ttaaaaaaat ctgagtaatt gtcaaatatt aaaagaaaga tattcttcct     2400

gtaaggaata cagtttttag tcaaagtggc cattacatcc tctttttaat ttacataata     2460

cagatacttg agaaagttgt tgtggtgttg tatgccaaga aaattctttt tattggtgcc     2520

tatattgtaa caattatttt taatgcattg tattttgaag taacggttca gttaaatttt     2580

tcacctgctg tgtaactgaa acacaattac agtttataat catctgtaga agtctggaga     2640

taattttgca actcatgtta tgggttaaat gaatattttt gtaaaagtaa aagcaacaaa     2700

tttataaatt gattatttga aactttacaa cacaattgca tcccaaatac aaattgtatt     2760

gcttattcat tatagctatt cgtcctgtaa tctgtttcta ggtgaagcat actccagtgt     2820

tttaggggtt ttgaaaataa atatttaaat ttcacagtca aaaaaaaaaa aaaaa          2875


<210>  2335
<211>  3121
<212>  DNA
<213>  homo sapiens

<400>  2335
accgcctccc aggccaggcg agcaggcggg tggctggggc gcctccacct cctcttccta       60

aagcggcgag gcgcagagga gcggcatcac tcgagcccag gtcccagcca ccaccactca      120

cagcgctcgg cgttcaggaa gaggagcagc agcggaggcg gctgcttcag cggcgggcgg      180

gcgccagaaa ggccccgatc gaaaagcctg ggagggccgc cgaactaccc ccggagggag      240

gagccagtcc gaacccaagg cgccaccgcc gcagaagcgg agcgaggcag cattcgcctc      300

catggcccac tcgccggtgg ctgtccaagt gcctgggatg caggggtcta aattatggat      360

aataatggaa tacctgggcg gtggttcagc actggatctt cttcgagctg gtccatttga      420

tgagttccag attgctacca tgctaaagga aattttaaaa ggtctggact atctgcattc      480

agaaaagaaa attcaccgag acataaaagc tgccaatgtc ttgctctcag aacaaggaga      540

tgttaaactt gctgattttg gagttgctgg tcagctgaca gatacacaga ttaaaagaaa      600

tacctttgtg ggaactccat tttggatggc tcctgaagtt attcaacagt cagcttatga      660

ctcaaaagct gacatttggt cattgggaat tactgctatt gaactagcca agggagagcc      720

acctaactcc gatatgcatc caatgagagt tctgtttctt attcccaaaa acaatcctcc      780

aactcttgtt ggagacttta ctaagtcttt taaggagttt attgatgctt gcctgaacaa      840

agatccatca tttcgtccta cagcaaaaga acttctgaaa cacaaattca ttgtaaaaaa      900

ttcaaagaag acttcttatc tgactgaact gatagatcgt tttaagagat ggaaggcaga      960

aggacacagt gatgatgaat ctgattccga gggctctgat tcggaatcta ccagcaggga     1020

aaacaatact catcctgaat ggagctttac caccgtacga aagaagcctg atccaaagaa     1080

agtacagaat ggggcagagc aagatcttgt gcaaaccctg agttgtttgt ctatgataat     1140

cacacctgca tttgctgaac ttaaacagca ggacgagaat aacgctagca ggaatcaggc     1200

gattgaagaa ctcgagaaaa gtattgctgt ggctgaagcc gcctgtcccg gcatcacaga     1260

taaaatggtg aagaaactaa ttgaaaaatt tcaaaagtgt tcagcagacg aatcccccta     1320

agaaacttat tattggcttc tgtttcatat ggacccagag agccccacca aacctacgtc     1380

aagattaaca atgcttaacc catgagctcc atgtgccttt tggatctttg caacactgaa     1440

gatttggaag aagctattaa actattttgt gatggcgttt atcattttat attttgaaag     1500

gattattttg taaggaataa cttttaatac tatagtttca cctgtattct agtaaatgtt     1560

gagacaccgt tttgctttta agtatcccta tttcttaagt tacgaggatg aatacctttc     1620

acattttgat ctttagttga ctctacagtc atgaaacata caggtctttc aaagtcattc     1680

tcaatattca gcttttgtaa attatcaagc ttcaaaaagc tttttttttt aaaaaaaaac     1740

atgcatattc taaaaatgac tattggtggg gaggtgtaaa taagtcatac cttcttaaaa     1800

cagaaaattt aagtaaagtc ttttaaatga aacctgtaaa agtattgact cttctaccaa     1860

gttggtatga tattccaggc agctcaatga ttatcacatt tgagaccctg tgtttgaagc     1920

atttacaggc aatgtacagc aacagaggta cctcttggtg tatagtattt acattctctt     1980

ttaggtagaa gaggcaattt tacccttatt tcacatggtt agaaatttaa agcaagatca     2040

tttacccaag gataggtgtt tggtaatgtt gaaggagtta gtctggcttc atgttttaca     2100

tcttcaacta aaatcccata ctatctgctt ggatttggag agccaaaaaa taaagctgat     2160

tgtcatgtga ttaaatatct gatcaacagg tatgaatata acttaaatca gcatattttt     2220

gccatggtaa taaattgtcc tataaactat ttatatattt ttgttcttca taattatcac     2280

taataagcat cagtttgttg tttttaaaag gatatttaag tgagcatttt ctagttcata     2340

tgaaaataac catagtacag gatgatttct gtccacacaa aggttaaatt agattgcaca     2400

gttaattttc acttatattt atggtactat tatgtgggtg atgccttttt cttttaagcc     2460

cagtacatat attatgcctg cctaagttct gaactggggc tgtatttcag tagttgtaga     2520

attattgata tttagttttg atagctaatg tttaattgtt tggatctgca cagtttggtt     2580

tttgcacaaa agtcatttaa aaaaatctga gtaattgtca aatattaaaa gaaagatatt     2640

cttcctgtaa ggaatacagt ttttagtcaa agtggccatt acatcctctt tttaatttac     2700

ataatacaga tacttgagaa agttgttgtg gtgttgtatg ccaagaaaat tctttttatt     2760

ggtgcctata ttgtaacaat tatttttaat gcattgtatt ttgaagtaac ggttcagtta     2820

aatttttcac ctgctgtgta actgaaacac aattacagtt tataatcatc tgtagaagtc     2880

tggagataat tttgcaactc atgttatggg ttaaatgaat atttttgtaa aagtaaaagc     2940

aacaaattta taaattgatt atttgaaact ttacaacaca attgcatccc aaatacaaat     3000

tgtattgctt attcattata gctattcgtc ctgtaatctg tttctaggtg aagcatactc     3060

cagtgtttta ggggttttga aaataaatat ttaaatttca cagtcaaaaa aaaaaaaaaa     3120

a                                                                     3121


<210>  2336
<211>  4079
<212>  DNA
<213>  homo sapiens

<400>  2336
gagggggcgg ggaggcgcgg gcgggtgtgc gcgcgccggg cgtgggtgtg ggtgggggta       60

accggcgcgg gcgccgagat agcgccgggc agagggaccc ggctaccctg gacagcgcat      120

cgccgcccgc ccgggtcgcc gcgccacagc cgctgcggat catggaacat ctaaaggcct      180

ttgatgatga aatcaatgct tttttggaca atatgtttgg accgcgagat tctcgagtca      240

gagggtggtt catgttggac tcttaccttc ctaccttttt tcttactgtc atgtatctgc      300

tctcaatatg gctgggtaac aagtatatga agaacagacc tgctctttct ctcaggggta      360

tcctcacctt gtataatctt ggaatcacac ttctctccgc gtacatgctg gcagagctca      420

ttctctccac ttgggaagga ggctacaact tacagtgtca agatcttacc agcgcagggg      480

aagctgacat ccgggtagcc aaggtgcttt ggtggtacta tttctccaaa tcagtagagt      540

tcctggacac aattttcttc gttttgcgga aaaaaacgag tcagattact tttcttcatg      600

tatatcatca tgcttctatg tttaacatct ggtggtgtgt cttgaactgg ataccttgtg      660

gacaaagttt ctttggacca acactgaaca gttttatcca cattcttatg tactcctact      720

atggactttc tgtgtttcca tctatgcaca agtatctttg gtggaagaaa tatctcacac      780

aggctcagct ggtgcagttc gtgctcacca tcacgcacac catgagcgcc gtcgtgaaac      840

cgtgtggctt ccccttcggt tgtctcatct tccagtcatc ttatatgcta acgttagtca      900

tcctcttctt aaatttttac gttcagacat accgaaaaaa gccaatgaag aaagatatgc      960

aagagccacc tgcagggaaa gaagtgaaga atggtttttc caaagcctac ttcactgcag     1020

caaatggagt gatgaacaag aaagcacaat aaaaatgagt aacagaaaaa gcacatatac     1080

tagcctaaca gattggcttg ttttaaagca aagactgaat tgaaggttac atgttttagg     1140

ataaactaat ttcttttgag ttcataaatc atttgtaccc agaatgtatt aatatattgc     1200

tattaggtta atctgttaac tgaatgcttt gatcagcatt gaggtgatgc tcacctccga     1260

ggacctcaga actggtgcag cttctctctc cctccctccc acagactgaa cctttcgcca     1320

gaagctgtcc ttataacgcc ttatacgcat acacagccag gaaacgtgga gcattgtttc     1380

tcacagagag tctccaaata aaaagggttt tgttcagatt aaaatgttta caacaaaatg     1440

ttaattatat tctaaataca gggtatgttc taatctatat taagcaataa tgccagtgca     1500

taatcattcc atttgttcct ttagcaatca accccagaaa atattaaaat gggatcatac     1560

acagaagata gaaaaatcta gcaaaacttc tctttctgta agccagagtc ttgtctatca     1620

gattcccaca accactcctg attctaaatt tagtgatatg gtaatgaaat tggtatttat     1680

tttaaatatt agttattcta aggagaaaaa aatgcttctg caagattttc ataattcagg     1740

ggctgtggat aggattgttc ctctgtttcc ctaatcattc atctgttcat gtctccctct     1800

tgtgccagtc agcctaggtt atacagatgc catgctccac accacgagca gtgtacaaat     1860

ctggctgccc gtttactttc tgagcaagca ctggagtcca ctccgacctt tttctttgaa     1920

catgcatgct gctggaatat gtataaatca gaactagcag aagtagcaga gtgatgggag     1980

caaaataggc actgaattcg tcaactcttt tttgtgagcc tacttgtgaa tattacctca     2040

gatacctgtt gtcactcttc acaggttatt taagtttttg aagctgggag gaaaaagatg     2100

gagtagcttg gaaagattcc agcactgagc cgtgggccgg tcatgagcca cgataaaaaa     2160

tgccagtttg gcaaactcag cactcctgtt ccctgctcag gtatatgcga tctctaccga     2220

gaagcaagca caaaagtaga caaaagtatt aatgagtatt tcctttctcc ataagtgcag     2280

gactgttact cactactaaa ctctaccaag aatggaaaca aagaatattt tctgaagatt     2340

tttttgaaga ttaatttata ccctataaaa taaaacttgt tagcttcgat gaagtcactt     2400

catcttctct cctgccttat ttttttaaat aagtttttag gtcctgacac tgacatcaaa     2460

tacatgcaca ccagaaaggc atttccacca ccgtccccac tcattagcgt ccagagtgcc     2520

tttctctctc ggcttttttt cccccctgag ctctagtttt aaactttctc ctgttaaaaa     2580

aattgtactt ttatttcatg taaactgccc ctctgaggat ttgggcatat tttttggaag     2640

gtgcctaatg cttaggatag tctctagggt gatgcactgc acctgcttcc ttcccttcag     2700

tgcggccgac ccatttctgt tgaacagatg tctcctgtgt gatgcccctg actcttacat     2760

ttatctttct aaatcatttt ctgaagctga cttgctctag ggtgcttcat caccacttcc     2820

atcttgcatc accttataac tgttctgtct tgttctctcc cagcaattta ttttaaaaca     2880

agggctagct tcaagcatga ctgttaatgg ctcctctgtg acaaaacaca agttggacca     2940

aggagaaagc cctttggaga aactggaccc tagttcagtt tagatctcaa atataggctg     3000

aaatctctta ccaaagtgcg ttccagataa aaatgagact tagaagacag actggtctaa     3060

tatgctcact ggtcatcaca ttcagcttat tcttacgtgc cagtgaggcc ctaaggtctc     3120

agtgcatagc atacctgcca ctctggatgt tttcctgggc ttcatatctg tatggcaagg     3180

agggagctgt ccttcagcag acaaagtcaa gcagctttaa gtacaaggca gcttgaaacc     3240

tctctgatga aagtgaaaaa tgtgggtagc ttatactttc aaactaatgc cagtgactag     3300

agagaggttt cattcatgat gtgtatttcc aatttggtct tcaattcaag agatgcttca     3360

taaaacactt atagccttaa accattcaag ggctaattaa aaaaatagtt atgaaatctt     3420

agccacaaaa aataaatcag gtaaacattt taacctgtcg ttaagtgttg taacttcaaa     3480

aaaccaaaat gcttatttta atgtgatttt tctaaaacta ttgaaaaatt aatatttcta     3540

taatctatta aaaaaaatgg agaatgtttt ctctcaaatt tcctctgacc catgggaatg     3600

aaaatactta aatactgtaa agcatatcta ttaataattc ccccaatttt ttaaactaac     3660

aaaatggaat gttaactgaa tggaattaaa catagcaatt gtcaagccat caaaattata     3720

tatcgaacca cttaggcatg ttacggggta aagtcctcac ccctgcattt gagaaatatt     3780

ttattatttt tattttaagg caaaacagtg tttactgtga tgggcagaac agccttttgt     3840

atctaggagt ccatttgagt tctttccaat atttccatat cgttcataaa tgtgtctggg     3900

ggcttccttg tttggaaaat atggatatcg ctttgttttc ctttgaaagt aattatatct     3960

taagaacata gtatcatgaa tggagtagac agggaggctg cagaagccat ttctctttgt     4020

agataaaaag cattatctat gattgttgta taataaattg atttttacat taaaaaaaa      4079


<210>  2337
<211>  2908
<212>  DNA
<213>  homo sapiens

<400>  2337
cgggcgccgc aggagcgagt gagctgggag cgaggggcga aggcgcggag aagcccggcc       60

gcccggtggg cggcagaagg ctcagccgag gcggcggcgc cgactccgtt ccactctcgg      120

cccggatcca ggcctccggg ttcccaggcg ctcacctccc tctgacgcac tttaaagagt      180

ctcccccctt ccacctcagg gcgagtaata gcgaccaatc atcaagccat ttaccaggct      240

tcggaggaag ctgtttatgt gatccccgca ctaattaggc tcatgaacta acaaatcgtt      300

tgcacaactt gtgaagaagc gaacacttcc atggattgtc cttggactta gggcgccctg      360

cccgcctttt gcagaggaga aaaaactttt tttttttttt gcctcccccg agaactttcc      420

ccccttctcc tccctgcctc taactccgat ccccccacgc catctcgcca aaaaaaaaaa      480

aaaaaaaaaa aaagaaaaaa aaagaaaaaa aaagaaaaaa aattacccca atccacgcct      540

gcaaattctt ctggaaggat tttcccccct ctcttcaggt tgggcgcgtt tggtgcaaga      600

ttctcgggat cctcggcttt gcctctccct ctccctcccc cctcctttcc tttttccttt      660

cctttccttt ctttcttcct ttccttcccc ccacccccac ccccacccca aacaaacgag      720

tccccaattc tcgtccgtcc tcgccgcggg cagcgggcgg cggaggcagc gtgcggcggt      780

cgccaggagc tgggagccca gggcgcccgc tcctcggcgc agcatgttcc agccggcgcc      840

caagcgctgc ttcaccatcg agtcgctggt ggccaaggac agtcccctgc ccgcctcgcg      900

ctccgaggac cccatccgtc ccgcggcact cagctacgct aactccagcc ccataaatcc      960

gttcctcaac ggcttccact cggccgccgc cgccgccgcc ggtaggggcg tctactccaa     1020

cccggacttg gtgttcgccg aggcggtctc gcacccgccc aaccccgccg tgccagtgca     1080

cccggtgccg ccgccgcacg ccctggccgc ccacccccta ccctcctcgc actcgccaca     1140

ccccctattc gcctcgcagc agcgggatcc gtccaccttc tacccctggc tcatccaccg     1200

ctaccgatat ctgggtcatc gcttccaagg gaacgacact agccccgaga gtttcctttt     1260

gcacaacgcg ctggcccgaa agcccaagcg gatccgaacc gccttctccc cgtcccagct     1320

tctaaggctg gaacacgcct ttgagaagaa tcactacgtg gtgggcgccg aaaggaagca     1380

gctggcacac agcctcagcc tcacggaaac tcaggtaaaa gtatggtttc agaaccgaag     1440

aacaaagttc aaaaggcaga agctggagga agaaggctca gattcgcaac aaaagaaaaa     1500

agggacgcac catattaacc ggtggagaat cgccaccaag caggcgagtc cggaggaaat     1560

agacgtgacc tcagatgatt aaaaacataa acctaacccc acagaaacgg acaacatgga     1620

gcaaaagaga cagggagagg tggagaagga aaaaacccta caaaacaaaa acaaaccgca     1680

tacacgttca ccgagaaagg gagagggaat cggagggagc agcggaatgc ggcgaagact     1740

ctggacagcg agggcacagg gtcccaaacc gaggccgcgc caagatggca gaggatggag     1800

gctccttcat caacaagcga ccctcgtcta aagaggcagc tgagtgagag acacagagag     1860

aaggagaaag agggagggag agagagaaag agagagaaag agagagagag agagagagag     1920

agaaagctga acgtgcactc tgacaagggg agctgtcaat caaacaccaa accggggaga     1980

caagatgatt ggcaggtatt ccgtttatca cagtccactt aaaaaatgat gatgatgata     2040

aaaaccacga cccaaccagg cacaggactt ttttgttttt tgcacttcgc tgtgtttccc     2100

ccccatcttt aaaaataatt agtaataaaa aacaaaaatt ccatatctag ccccatccca     2160

cacctgtttc aaatccttga aatgcatgta gcagttgttg ggcgaatggt gtttaaagac     2220

cgaaaatgaa ttgtaatttt cttttccttt taaagacagg ttctgtgtgc tttttatttt     2280

gatttttttt cccaagaaat gtgcagtctg taaacacttt ttgatacctt ctgatgtcaa     2340

agtgattgtg caagctaaat gaagtaggct cagcgatagt ggtcctctta cagagaaacg     2400

gggagcagga cgacgggggg gctgggggtg gcgggggagg gtgcccacaa aaagaatcag     2460

gacttgtact gggaaaaaaa cccctaaatt aattatattt cttggacatt ccctttccta     2520

acatcctgag gcttaaaacc ctgatgcaaa cttctccttt cagtggttgg agaaattggc     2580

cgagttcaac cattcactgc aatgcctatt ccaaacttta aatctatcta ttgcaaaacc     2640

tgaaggactg tagttagcgg ggatgatgtt aagtgtggcc aagcgcacgg cggcaagttt     2700

tcaagcactg agtttctatt ccaagatcat agacttacta aagagagtga caaatgcttc     2760

cttaatgtct tctataccag aatgtaaata tttttgtgtt ttgtgttaat ttgttagaat     2820

tctaacacac tatatacttc caagaagtat gtcaatgtca atattttgtc aataaagatt     2880

tatcaatatg ccctcaaaaa aaaaaaaa                                        2908


<210>  2338
<211>  2346
<212>  DNA
<213>  homo sapiens

<400>  2338
agtgctgctc ttttccccag tgttttcgga gggatgacgg gggatggtag gggttggcct       60

ctgtctgcga ctgttactgt tctttcgttt taaacgaacg ctggacagga tttgcgtgct      120

cttcctcctc gggtggcatc ggaagccgcg cagtgatgga tctctcttta tagagaggtt      180

atacattggc tcttcaaaga cgttcacctc atcagagaaa tccctgactc ctttgcagtg      240

gtgtagacat gtcctagata acccaactcc tgagatggaa gcagcgagac gttccctgtg      300

ctttagactg gagcaaggtt acacttccag gggctcccca ctcagtcccc agtcatctat      360

cgacagtgag ctgagtactt cagaattgga ggatgattct atctccatgg gatataaatt      420

acaggacctc actgatgttc agatcatggc tcgtctgcaa gaagaaagtc tcaggcaaga      480

ttatgcttct acttcagcat ctgtatcaag acatagttcc agtgtgtcat tgagttcagg      540

aaaaaaaggg acatgtagtg atcaagaata tgaccaatac agtctggagg atgaagagga      600

atttgatcat ttgccaccac ctcagcctcg tcttccaaga tgttcccctt tccaaagagg      660

aattccccat tcacagactt tctccagcat tcgggagtgt aggaggagcc ccagttccca      720

gtattttcct tcaaataatt accagcagca acagtattat tcacctcaag cccaaactcc      780

agatcagcaa ccaaatagga ccaatggaga taagctccga agaagtatgc ctaacctagc      840

ccggatgcca agtacaactg ccattagtag caacattagt tctccggtca ccgtgcgaaa      900

tagtcagagt tttgactcaa gcttgcatgg agctggaaat ggaatttcaa gaatacaatc      960

ttgtattcca tcaccgggac agcttcaaca cagggtccac agcgtggggc atttcccagt     1020

gtctatccga cagcctctta aagccacagc ctatgtgagt ccaaccgttc aaggcagcag     1080

taacatgcct ttatcaaacg gcttacagct gtattccaac acaggaatcc ccacaccgaa     1140

caaagctgca gcttctggga taatgggtcg cagtgcactc ccaagacctt cgttggcaat     1200

aaatgggagt aacctgcctc gaagcaaaat tgcacaacct gttagaagtt ttcttcagcc     1260

tccaaagcct ctgtcttcac tcagcactct gagggatgga aattggagag atggttgcta     1320

ctaatgcagt tttatgtacc cttgaaaaat gggaaagaag taaaaatgag ggttgtgtta     1380

cctagctggc tgggtagcag tggatgttgg gatattcttt cccttttgtg ttttaatata     1440

tttactgcat tgtttctcaa tggaccagtc accagagact aattattgca cttaaatatt     1500

tgcctgagat actgcaacat tctcaaaccc atggttgcag tattgtgaca cttagatcta     1560

ggaagttttt gtagaactgc tctgtacctg aatacttttt gagagaatta agatgtatca     1620

ataatgcttt gccatatgag ttttttaaag taacttgttc aatttactca cgtgttctaa     1680

acatctttcc attacatgtt ctgtatttta atacattgca tattgacaac taggttctat     1740

aatgtatgct ttgaaattta cttttttata gtttacagga attttatttt ttgtgcctat     1800

ttctttttac acctatgtga accactatgg aacaacttaa attttgtgcc ataaaaatat     1860

ttttgtggta aggtactatt tttttagctc tagggatata tcagcaaaaa cacatcatgc     1920

aatttgagac acataatttt gtgttgaatg agcacaacat aatttgaagc attgcaagga     1980

gataaccaga cagcagaatt aaatggtcct gtctttttca tttttaattt attgtcatac     2040

atgggtttca tatttataac ggcatcatga gctcattgca cttaatacct gcaatgtttg     2100

ctactgtacc acaattgatt ttcaatactt tattacgaag gatgaaactg taatgtttta     2160

ttaacaatgc ttctggaaat gaatgcattt taaagcaaat aaatcttttt gatagacctt     2220

ttacaaaatc catttgcact aatgaatgct ttcttatggc atataactta atatttgtta     2280

ctgtgtacac tgctgttttg gaatgttcag aaataaagac tctatttcag caatatcagg     2340

tcatgc                                                                2346


<210>  2339
<211>  2908
<212>  DNA
<213>  homo sapiens

<400>  2339
agagacgaga agagaggagg ggaggcctcc tccgccgccg ccatcttgga ccgggcccgg       60

tcagcttccg cggagccatc ggcagacgcc gcggcctccc ttgagccccg acccccgtcg      120

tcagaacaac cccgggccca ctcccccaac cccacttccg cttcgcgccg ctatcgcgat      180

agcgcccggg cccggggcgc gagaaaaagg cggcgggcgc tcgcctcccc cgcctgtcgc      240

gatacgctcc tcagcggcgg cgccagctcc tgtgcgtccg tctccaagag agtatgaaga      300

gagtgcgtct gtagggcagg gaagatggcg gacaagcgca aactccaagg tgagattgat      360

cgctgcctca agaaggtgtc cgagggcgtg gagcagtttg aagatatttg gcagaagctc      420

cacaatgcag ccaacgcgaa ccagaaagaa aagtatgagg ctgacctaaa gaaggagatt      480

aagaagctac aacggctgag ggaccaaatc aagacatggg tagcgtccaa cgagatcaag      540

gacaagaggc agcttataga caaccgcaag ctcattgaga cgcaaatgga acggttcaaa      600

gttgtggaac gagagaccaa aaccaaagct tacagcaaag agggcctggg cctggcccag      660

aaggtagatc ctgcccagaa ggagaaggaa gaggttggcc agtggctcac gaataccatc      720

gacacgctca acatgcaggt ggaccagttt gagagtgaag tggagtcact gtcagtgcag      780

acacgcaaga agaagggcga caaggataag caggaccgga ttgagggctt gaagcggcac      840

atcgagaagc accgctacca cgtgcgcatg ctagagacca tcctgcgcat gctggacaat      900

gactccatcc tcgttgacgc catccgcaag atcaaggacg acgttgagta ctatgttgac      960

tcatcccagg accccgactt cgaggagaac gagtttctct acgatgacct ggacctcgag     1020

gacattccac aggcgctggt cgccacctcc ccccccagcc acagccacat ggaggatgag     1080

atcttcaacc agtccagcag cacgcccacc tcaaccacct ccagctctcc catcccgccc     1140

agcccagcca actgtaccac ggaaaactct gaagatgata agaagagggg acgttccaca     1200

gacagtgaag tcagccagtc tccagccaaa aacggctcca agcctgtcca cagcaaccag     1260

caccctcagt ccccagctgt gccgcccacc tacccctccg gccccccgcc tgctgcctct     1320

gccttgagca ccactcctgg caacaatggg gtccccgccc ccgcagcacc cccaagtgcc     1380

ctgggcccca aggccagtcc agctcccagc cacaactcgg gcacccctgc tccctatgcc     1440

caggctgtgg ccccaccagc tcccagtggg cccagcacga cccagccccg gccccccagc     1500

gtccagccta gcggaggcgg aggcggcggc agcggaggtg gagggagcag cagcagtagt     1560

aacagcagtg ccggtggagg ggctggcaag cagaatggcg ccaccagtta cagctcagtt     1620

gtggcagaca gcccggcaga ggtggctttg agcagcagtg ggggcaacaa tgccagcagc     1680

caggccttgg gccccccttc cggcccccac aacccacctc ccagcacctc gaaggaaccc     1740

agtgcggcag ccccaacggg ggctgggggc gtggccccag gctcagggaa caactcaggg     1800

ggacccagcc tcctggtgcc actgcctgtg aatcctccca gctccccaac gcccagcttc     1860

agtgatgcca aggcagccgg tgccctgctc aatgggcctc cacagttcag caccgcccca     1920

gaaatcaagg cccctgagcc tctgagctcc ttgaagtcca tggcggaacg ggcagccatc     1980

agctctggca ttgaggaccc tgtgccaacg ctgcacctga ccgagcgaga catcatcctg     2040

agcagtacat cagcacctcc ggcctcagcc cagccgcccc tgcagctgtc agaggtgaac     2100

ataccgctgt cgctgggtgt ctgtccactg ggccctgtgc ccctcaccaa ggagcagctc     2160

tatcagcagg ccatggaaga ggccgcctgg caccacatgc ctcacccctc tgactctgag     2220

cgtattcggc agtacctccc ccggaacccc tgtccgacgc ccccctacca ccaccagatg     2280

ccacccccac actcggacac tgtggaattc taccagcgcc tgtcgaccga gacactcttc     2340

ttcatcttct actatctgga gggcactaag gcacagtatc tggcagccaa ggccctaaag     2400

aagcagtcat ggcgattcca caccaagtac atgatgtggt tccagaggca cgaggagccc     2460

aagaccatca ctgacgagtt tgagcagggc acctacatct actttgacta cgagaagtgg     2520

ggccagcgga agaaggaagg cttcaccttt gagtaccgct acctggagga ccgggacctc     2580

cagtgacacc ggcccctccc tctacccacc cccttccccc gcatgctgat ccccctgccc     2640

aggtgagggc cctgccctgg aagactggag ggaggcccca agccacgggg catccccctc     2700

tcccaggaag cagggagggg gccgggaggt tttcctctca gccccaccct gggggcccgg     2760

gggcgagggc tgccccctcc tcccctcccc agtgagggac attttttggt aaacctattt     2820

tcattttgga aaatatttat gaataaatag ttttatatga cggctggcag cagcggcctc     2880

tcctgtaaaa aaaaaaaaaa aaaaaaaa                                        2908


<210>  2340
<211>  1064
<212>  DNA
<213>  homo sapiens

<400>  2340
cgagccgcga agattgtttt tgtcccgccg aaatcgagca aagcacgctg gaacttgtag       60

tccttgaggc cccttcccta ggtccttcga gctactccgt ctggccccgc cttttctctg      120

ctctcctgaa cctttaggct tgtctcggcc catttgaaga ccaggaagtt gatcaatccc      180

gaggctgctg agagacggtg gcgcgattgg gacagtcgcc agggatggct gagcgtgaag      240

atgcagcggg tgtccgggct gctctcctgg acgctgagca gagtcctgtg gctctccggc      300

ctctctgagc cgggagctgc ccggcagccc cggatcatgg aagagaaagc gctagaagtt      360

tatgatttga ttagaactat ccgggaccca gaaaagccca atactttaga agaactggaa      420

gtggtctcgg aaagttgtgt ggaagttcag gagataaatg aagaagaata tctggttatt      480

atcaggttca cgccaacagt acctcattgc tctttggcga ctcttattgt tggaaatcta      540

catttctgaa ggaacccact caacagaaga agacatcaat aagcagataa atgacaaaga      600

gcgagtggca gctgcaatgg aaaaccccaa cttacgggaa attgtggaac agtgtgtcct      660

tgaacctgac tgatagctgt tttaagagcc actggcctgt aattgtttga tatatttgtt      720

taaactcttt gtataatgtc agagactcat gtttaataca taggtgattt gtacctcaga      780

gtatttttta aaggattctt tccaagcgag atttaattat aaggtagtac ctaatttgtt      840

caatgtataa cattctcagg atttgtaaca cttaaatgat cagacagaat aatattttct      900

agttattatg tgtaagatga gttgctattt ttctgatgct cattctgata caactatttt      960

tcgtgtcaaa tatctactgt gcccaaatgt actcaattta aatcattact ctgtaaaata     1020

aataagcaga tgattcttat aatgaaaaaa aaaaaaaaaa aaaa                      1064


<210>  2341
<211>  3558
<212>  DNA
<213>  homo sapiens

<400>  2341
ccgcggccgg gccgagccgc aggcgctgcc cgagccgcgg gcgctggagc ggctgtcggc       60

gcggtggcag gcgggagcca ggagtccggg gctcgggcgg gcggagcgca gcgcggggac      120

gcggcggagc gggccccgcg gctcggcggg ggccggcaga caggtgtgcc ggcggcgggc      180

ggctcgcgct caggcggctc caggccgggc ccggggtccg gagcggggag ccgggagccg      240

agcgaggacc cggcgcccgc agtccagtct tggccgcgcc cgtgctcggc ttggccgcgg      300

ggtgcgggga ccacggcccg gccgggccac ccgaagccta gtgctgggcc gggccgggcc      360

ggggtgggtg ggggcccgcc cggcccgccc atgggctcag gatgccggtg cggaggggcc      420

acgtcgcgcc gcagaacacc ttcctggaca ccatcatccg caagtttgag ggccagagcc      480

gtaagttcat catcgccaac gctcgggtgg agaactgcgc cgtcatctac tgcaacgacg      540

gcttctgcga gctgtgcggc tactcgcggg ccgaggtgat gcagcgaccc tgcacctgcg      600

acttcctgca cgggccgcgc acgcagcgcc gcgctgccgc gcagatcgcg caggcactgc      660

tgggcgccga ggagcgcaaa gtggaaatcg ccttctaccg gaaagatggg agctgcttcc      720

tatgtctggt ggatgtggtg cccgtgaaga acgaggatgg ggctgtcatc atgttcatcc      780

tcaatttcga ggtggtgatg gagaaggaca tggtggggtc cccggctcat gacaccaacc      840

accggggccc ccccaccagc tggctggccc caggccgcgc caagaccttc cgcctgaagc      900

tgcccgcgct gctggcgctg acggcccggg agtcgtcggt gcggtcgggc ggcgcgggcg      960

gcgcgggcgc cccgggggcc gtggtggtgg acgtggacct gacgcccgcg gcacccagca     1020

gcgagtcgct ggccctggac gaagtgacag ccatggacaa ccacgtggca gggctcgggc     1080

ccgcggagga gcggcgtgcg ctggtgggtc ccggctctcc gccccgcagc gcgcccggcc     1140

agctcccatc gccccgggcg cacagcctca accccgacgc ctcgggctcc agctgcagcc     1200

tggcccggac gcgctcccga gaaagctgcg ccagcgtgcg ccgcgcctcg tcggccgacg     1260

acatcgaggc catgcgcgcc ggggtgctgc ccccgccacc gcgccacgcc agcaccgggg     1320

ccatgcaccc actgcgcagc ggcttgctca actccacctc ggactccgac ctcgtgcgct     1380

accgcaccat tagcaagatt ccccaaatca ccctcaactt tgtggacctc aagggcgacc     1440

ccttcttggc ttcgcccacc agtgaccgtg agatcatagc acctaagata aaggagcgaa     1500

cccacaatgt cactgagaag gtcacccagg tcctgtccct gggcgccgac gtgctgcctg     1560

agtacaagct gcaggcaccg cgcatccacc gctggaccat cctgcattac agccccttca     1620

aggccgtgtg ggactggctc atcctgctgc tggtcatcta cacggctgtc ttcacaccct     1680

actcggctgc cttcctgctg aaggagacgg aagaaggccc gcctgctacc gagtgtggct     1740

acgcctgcca gccgctggct gtggtggacc tcatcgtgga catcatgttc attgtggaca     1800

tcctcatcaa cttccgcacc acctacgtca atgccaacga ggaggtggtc agccaccccg     1860

gccgcatcgc cgtccactac ttcaagggct ggttcctcat cgacatggtg gccgccatcc     1920

ccttcgacct gctcatcttc ggctctggct ctgaggagct gatcgggctg ctgaagactg     1980

cgcggctgct gcggctggtg cgcgtggcgc ggaagctgga tcgctactca gagtacggcg     2040

cggccgtgct gttcttgctc atgtgcacct ttgcgctcat cgcgcactgg ctagcctgca     2100

tctggtacgc catcggcaac atggagcagc cacacatgga ctcacgcatc ggctggctgc     2160

acaacctggg cgaccagata ggcaaaccct acaacagcag cggcctgggc ggcccctcca     2220

tcaaggacaa gtatgtgacg gcgctctact tcaccttcag cagcctcacc agtgtgggct     2280

tcggcaacgt ctctcccaac accaactcag agaagatctt ctccatctgc gtcatgctca     2340

ttggctccct catgtatgct agcatcttcg gcaacgtgtc ggccatcatc cagcggctgt     2400

actcgggcac agcccgctac cacacacaga tgctgcgggt gcgggagttc atccgcttcc     2460

accagatccc caatcccctg cgccagcgcc tcgaggagta cttccagcac gcctggtcct     2520

acaccaacgg catcgacatg aacgcggtgc tgaagggctt ccctgagtgc ctgcaggctg     2580

acatctgcct gcacctgaac cgctcactgc tgcagcactg caaacccttc cgaggggcca     2640

ccaagggctg ccttcgggcc ctggccatga agttcaagac cacacatgca ccgccagggg     2700

acacactggt gcatgctggg gacctgctca ccgccctgta cttcatctcc cggggctcca     2760

tcgagatcct gcggggcgac gtcgtcgtgg ccatcctggg tatggggtgg ggggcgggca     2820

ctggactgga aatgccctct gcagcctcaa gaggtgcgag ccttctgaat atgcagtcac     2880

tggggctgtg gacctgggac tgcctgcagg gtcactgggc tcctttaatt cacctaaact     2940

caggccctcc aagcggggcc atggagagga gccccacgtg gggtgaggct gctgaactct     3000

ggggttccca cattctcctt cccttcagga tccgccacaa acagacactt tttgcttcct     3060

taaagtagga tcaaatctag atcctctagc ctgggcagta gaggaagaaa tgctagcctg     3120

gaagctcggc atttggtttc actaagggcc atgtggttcc ctgcagcctc atgcctggcc     3180

ccttgacaca tccaaagcaa agggagtcct gccccctccc cccacttcct ttctaccctg     3240

cctgtgcaca gtgggtgggt tggtgtgtct ggacactgag gacttcctcc ccctttgcct     3300

gtccttccct cggccctgtg tgcctcaggg cagatatagc aagctctttc gaccatagtt     3360

gatggtagga cattttagac tttgtttctc agctctgtac aaacacaaat acacaccccc     3420

acaaaactaa aatcaaagtt tcactacata acactgggcc ttactgcatg tggttcattc     3480

tagcatttct gttctgtgct gtgctaagct atactactgt atgttctttc agtaaaaaaa     3540

aaaaaaaaaa aaaaaaaa                                                   3558


<210>  2342
<211>  6419
<212>  DNA
<213>  homo sapiens

<400>  2342
agtctgcggg cctccggggc agcggcgagg ccggagcgtc gcggcggaga ggacgagacc       60

gggacaagac cagggcagga gggagccggc cagccgcgag aaccccgcac gcccggcaag      120

atgctgtcct ggcggctgca gacgggcccc gagaaggccg agctccagga gctcaacgcc      180

cggctctatg actacgtgtg tcgggtgcgg gagctggagc gcgaaaacct actcctggag      240

gaggagctgc gcggccggcg cgggcgagag ggcctgtggg ccgaggggca ggcccgctgc      300

gccgaggagg cgcgcagctt gcggcagcag ctggacgagc tgagctgggc cactgcgctg      360

gcggagggcg agcgggacgc tctgcggcgc gagctgcggg agctgcagcg cctggatgcg      420

gaggagcgcg ccgcccgcgg ccgcctggac gccgagctgg gtgcgcagca gcgcgagctg      480

caggaggcgc tgggcgcgcg cgccgccctc gaggcgctgc tgggccggct gcaggccgag      540

cgccgaggcc tcgacgcggc ccacgaacgc gacgtgaggg agctgcgcgc gcgcgccgcc      600

agccttacca tgcatttccg cgcccgcgcc accggccccg ccgcgccgcc gccacgcctg      660

cgggaggtgc acgacagcta cgcactgctg gtggccgagt cgtggcggga gacggtgcag      720

ctgtacgagg acgaggtgcg cgagctggag gaggcgctgc ggcgcggcca ggagagcaga      780

ctccaggcgg aggaagagac gcggctgtgc gcgcaggagg cagaggcgct gcggcgcgag      840

gcgctcgggt tggagcagct gcgcgcgcgg ctggaggacg cgctgctgcg gatgcgcgag      900

gagtacggga tacaggccga ggagcggcag agagtgattg actgcctgga ggatgagaag      960

gcaaccctca ccttggccat ggctgactgg ctgcgggact atcaggacct cctgcaggtg     1020

aagaccggcc tcagtctgga ggtggcgacc taccgggcct tattggaagg agaaagtaat     1080

ccagagatag tgatctgggc tgagcacgtt gaaaacatgc cgtcagaatt cagaaacaaa     1140

tcctatcact ataccgactc actactacag agggaaaatg aaaggaatct attttcaagg     1200

cagaaagcac ctttggcaag tttcaatcac agctcggcac tgtattctaa cctgtcaggg     1260

caccgtggat ctcagacggg cacatctatt ggaggtgatg ccagaagagg cttcttgggc     1320

tcgggatatt cttcctcggc cactacccag caggaaaact catacggaaa agccgtcagc     1380

agtcaaacca acgtcagaac tttctctcca acctatggcc ttttaagaaa tactgaggct     1440

caagtgaaaa cattccctga cagaccaaaa gccggagata caagggaggt ccccgtttac     1500

ataggtgaag attccacaat tgcccgcgag tcgtaccggg atcgccgaga caaggtggca     1560

gcaggtgctt cggaaagcac acggtcaaat gagaggaccg tcattctggg aaagaaaaca     1620

gaagtgaaag ccacgaggga gcaagaaaga aacagaccag aaaccatccg aacaaagcca     1680

gaagagaaaa tgttcgattc taaagagaag gcttccgagg agagaaacct aagatgggaa     1740

gaattgacaa agttagataa ggaagcgaga cagagagaaa gccagcagat gaaggagaag     1800

gctaaggaga aggactcacc gaaggagaag agcgtgcgag agagagaggt gccgattagt     1860

ctagaagtat cccaggacag aagagcagag gtgtccccga aaggtttgca gacgcctgtg     1920

aaggatgctg gtggtgggac cggtagagag gcagaagcaa gagagctacg gttcaggttg     1980

ggcaccagtg atgccactgg ttctctgcaa ggcgattcca tgacagaaac cgtagcagaa     2040

aacatcgtta ccagtatcct gaagcagttc actcagtctc cagagacaga agcatctgct     2100

gattcttttc cagacacaaa agtcacttac gtggacagga aagagcttcc tggggaaagg     2160

aaaacaaaga ctgaaatagt tgtggagtct aaactgactg aggatgttga tgtttccgat     2220

gaagctggcc tggactacct tttaagcaag gatattaagg aagtggggct gaaaggcaag     2280

tcagccgagc agatgatagg agacatcatc aacctcggcc tgaaagggag ggaggggaga     2340

gcaaaggtcg tcaacgtgga gatcgtggag gagcccgtga gttatgtcag cggggagaag     2400

ccggaggagt tttccgtccc attcaaagtg gaggaggtcg aagatgtgtc gccaggcccc     2460

tgggggttgg ttaaggagga ggaaggttat ggagaaagcg atgtcacatt ctcagttaat     2520

cagcatcgaa ggaccaagca gcctcaggag aacacgactc acgtggaaga agtgacagag     2580

gcaggtgatt cagagggcga gcagagttat tttgtgtcca ctccagatga acaccccggg     2640

gggcacgaca gagatgacgg ctcggtgtac gggcagatcc acatcgagga ggaatccacc     2700

atcaggtact cttggcagga tgaaatcgtg caggggactc gaaggaggac acagaaggac     2760

ggtgcagtgg gcgagaaggt tgtgaagccc ttggatgtcc cagcgccctc tctggagggg     2820

gacctgggtt ccactcactg gaaagaacaa gctagaagcg gtgaatttca tgccgaaccc     2880

acagtcattg aaaaagaaat taaaataccc cacgaattcc acacctccat gaagggcatc     2940

tcctccaagg agccccggca gcagctggtg gaggtcatcg ggcagctgga ggaaaccctt     3000

cccgagcgca tgagggagga gctgtccgcc ctcaccagag aggggcaggg tgggccgggg     3060

agcgtttccg tggatgtcaa gaaggtccag ggtgctggtg gcagttccgt gaccctggtt     3120

gctgaagtca acgtctcaca aactgtggat gccgatcggt tagacctgga ggagctgagc     3180

aaagatgagg ccagtgagat ggagaaggct gtggagtcgg tggttcggga gagcctgagc     3240

aggcaacgca gcccagcgcc tggcagccca gatgaggaag gtggagcgga ggccccggct     3300

gctggcattc gctttaggcg ttgggccacc cgggagctgt acatcccttc aggcgagagc     3360

gaggttgctg gtggggcctc tcacagctcg ggacagcgca ctccccaggg cccagtgtcg     3420

gccactgtgg aggtcagcag ccccacaggc tttgcccagt cacaggtgct ggaggatgtg     3480

agccaggctg caaggcacat aaaactcggc ccctctgaag tctggaggac tgagcgaatg     3540

tcatatgaag gacccactgc agaagtggtg gagatggatg tgagtaacgt agaggcgatc     3600

cgcagccgga cacaggaagc gggagctctc ggtgtgtctg accgtggttc ctggagagac     3660

gcggacagta ggaatgacca ggcagttggt gtgagcttta aggcctctgc tggggaagga     3720

gaccaggccc acagagaaca gggcaaggag caggccatgt ttgataagaa ggtgcagctc     3780

cagagaatgg tagaccaaag gtcggtgatt tcagatgaaa agaaagttgc cctcctctat     3840

ctagacaatg aggaggagga gaatgatggg cattggtttt aataagcaga aacattttgt     3900

tttaatggca gcctgttggc gacgtgccaa catccaaagg ccttaactta ttttaagagg     3960

ccgagggagt ctatgaaaat ctcccctttt ttactttttt aaagagtact cccggcatgg     4020

tcaatttcct ttatagttaa tccgtaaagg tttccagtta attcatgcct taaaaggcac     4080

tgcaatttta tttttgagtt gggactttta caaaacactt ttttccctgg agtcttctct     4140

ccacttctgg agatgaattt ctatgttttg cacctggtca cagacatggc ttgcatctgt     4200

ttgaaactac aattaattat agatgtcaaa acattaacca gattaaagta atatatttaa     4260

gagtaaattt tgcttgcatg tgctaatatg aaataacaga ctaacatttt aggggaaaaa     4320

taaatacaat ttagactcta aaaagtcttt tcaaaaagaa atgggaaata ggcagactgt     4380

ttatgttaaa aaaattcttg ctaaatgatt tcatctttag gaaaaaatta cttgccatat     4440

agagctaaat tcatcttaag acttgaatga attgctttct atgtacagaa ctttaaacaa     4500

tatagtattt atggcgagga cagctgtagt ctgttgtgat atttcacatt ctatttgcac     4560

aggttccctg gcactggtag ggtagatgat tattgggaat cgcttacagt accatttcat     4620

tttttggcac taggtcatta agtagcacac agtctgaatg cccttttctg gagtggccag     4680

ttcctatcag actgtgcaga cttgcgcttc tctgcacctt atcccttagc acccaaacat     4740

ttaatttcac tggtgggagg tagaccttga agacaatgaa gagaatgccg atactcagac     4800

tgcagctgga ccggcaagct ggctgtgtac aggaaaattg gaagcacaca gtggactgtg     4860

cctcttaaag atgcctttcc caaccctcca ttcatgggat gcaggtcttt ctgagctcaa     4920

gggtgaaaga tgaatacaat aacaaccatg aacccacctc acggaagctt tttttgcact     4980

ttgaacagaa gtcattgcag ttggggtgtt ttgtccaggg aaacagttta ttaaatagaa     5040

ggatgttttg gggaaggaac tggatatctc tcctgcagcc cagcaccgag atacccagga     5100

cgggcctggg gggcgagaaa ggcccccatg ctcatgggcc gcggagtgtg gacctgtaga     5160

taggcaccac cgagtttaag atactgggat gagcatgctt cattggattc attttatttt     5220

acacgtcagt attgttttaa agtttctgtc tgtaaagtgt agcatcatat ataaaaagag     5280

tttcgctagc agcgcatttt ttttagttca ggctagcttc tttcacataa tgctgtctca     5340

gctgtatttc cagtaacaca gcatcatcgc actgactgtg gcgcactggg gaataacagt     5400

ctgagctagc accaccctca gccaggctac aacgacagca ctggagggtc ttccctctca     5460

gattcacctg gaggccctca gacccccagg gtgcacgtct ccccaggtcc tgggagtggc     5520

taccgcaggt agtttctgga gagcacgttt tcttcattga taagtggagg agaaatgcag     5580

cacagctttc aagatactat tttaaaaaca ccatgaatca gatagggaaa gaaagttgat     5640

tggaatagca agtttaaacc tttgttgtcc atctgccaaa tgaactagtg attgtcagac     5700

tggtatggag gtgactgctt tgtaaggttt tgtcgtttct aatacagaca gagatgtgct     5760

gattttgttt tagctgtaac aggtaatggt ttttggatag atgattgact ggtgagaatt     5820

tggtcaaggt gacagcctcc tgtctgatga caggacagac tggtggtgag gagtctaagt     5880

gggctcagtt tgatgtcagt gtctgggctc atgacttgta aatggaagct gatgtgaaca     5940

ggtaattaat attatgaccc acttctattt actttgggaa atatcttgga tcttaattat     6000

catctgcaag tttcaagaag tattctgcca aaagtattta caagtatgga ctcatgagct     6060

attgttggtt gctaaatgtg aatcacgcgg gagtgagtgt gcccttcaca ctgtgacatt     6120

gtgacattgt gacaagctcc atgtccttta aaatcagtca ctctgcacac aagagaaatc     6180

aacttcgtgg ttggatgggg ccggaacaca accagtcttt ttgtatttat tgttactgag     6240

acaaaacagt actcactgag tgtttttcag tttcctactg gtggttttga tattgtttgt     6300

ttaagatgta tatttagaat gacatcatct aagaagctga ttttgctaaa ctcctgttcc     6360

ctacaatggg aaatgtcaca agaatgtgca aaaataaaaa tctgaggaaa aaacccaca      6419


<210>  2343
<211>  1321
<212>  DNA
<213>  homo sapiens

<400>  2343
cttttcccgg cacatgcgca ccgcagcggg tcgcgcgccc taaggagtgg cactttttaa       60

aagtgcagcc ggagaccagc ctacagccgc ctgcatctgt atccagcgcc aggtcccgcc      120

agtcccagct gcgcgcgccc cccagtcccg cacccgttcg gcccaggcta agttagccct      180

caccatgccg gtcaaaggag gcaccaagtg catcaaatac ctgctgttcg gatttaactt      240

catcttctgg cttgccggga ttgctgtcct tgccattgga ctatggctcc gattcgactc      300

tcagaccaag agcatcttcg agcaagaaac taataataat aattccagct tctacacagg      360

agtctatatt ctgatcggag ccggcgccct catgatgctg gtgggcttcc tgggctgctg      420

cggggctgtg caggagtccc agtgcatgct gggactgttc ttcggcttcc tcttggtgat      480

attcgccatt gaaatagctg cggccatctg gggatattcc cacaaggatg aggtgattaa      540

ggaagtccag gagttttaca aggacaccta caacaagctg aaaaccaagg atgagcccca      600

gcgggaaacg ctgaaagcca tccactatgc gttgaactgc tgtggtttgg ctgggggcgt      660

ggaacagttt atctcagaca tctgccccaa gaaggacgta ctcgaaacct tcaccgtgaa      720

gtcctgtcct gatgccatca aagaggtctt cgacaataaa ttccacatca tcggcgcagt      780

gggcatcggc attgccgtgg tcatgatatt tggcatgatc ttcagtatga tcttgtgctg      840

tgctatccgc aggaaccgcg agatggtcta gagtcagctt acatccctga gcaggaaagt      900

ttacccatga agattggtgg gattttttgt ttgtttgttt tgttttgttt gttgtttgtt      960

gtttgttttt ttgccactaa ttttagtatt cattctgcat tgctagataa aagctgaagt     1020

tactttatgt ttgtctttta atgcttcatt caatattgac atttgtagtt gagcgggggg     1080

tttggtttgc tttggtttat attttttcag ttgtttgttt ttgcttgtta tattaagcag     1140

aaatcctgca atgaaaggta ctatatttgc tagactctag acaagatatt gtacataaaa     1200

gaattttttt gtctttaaat agatacaaat gtctatcaac tttaatcaag ttgtaactta     1260

tattgaagac aatttgatac ataataaaaa attatgacaa tgtcctggac tggtaaaaaa     1320

a                                                                     1321


<210>  2344
<211>  6432
<212>  DNA
<213>  homo sapiens

<400>  2344
gagagccgta gtttcttcca ttctgttttg gacatgcgcg gggcgtaagg cgctttggcc       60

agagtggttt gatggttttg tgttagtctt cctgcagctg agcttccaca agacactttt      120

tccctttcag ccacccaata tctcgcgaga cttgctattc tgcgccccct cccaccttgc      180

gcttgcgcag atcttcaaag cagaaggtcg cgcttggagg aagtggcggc tttgagtccg      240

gtggcccaat cgctgttact acttctctga agctcctctc ggctgcttgc cgagacaccc      300

tgccgccaag atgcctcgaa ttatgatcaa ggggggcgta tggaggaata ccgaggatga      360

aattctgaaa gcagcggtaa tgaaatatgg gaaaaatcag tggtctagga ttgcctcatt      420

gctgcataga aaatcagcaa agcagtgcaa agccagatgg tatgaatggc tggatccaag      480

cattaagaag acagaatggt ccagagaaga agaggaaaaa ctcttgcact tggccaagtt      540

gatgccaact cagtggagga ccattgctcc aatcattgga agaacagcgg cccagtgctt      600

agaacactat gaatttcttc tggataaagc tgcccaaaga gacaatgaag aggaaacaac      660

agatgatcca cgaaaactta aacctggaga aatagatcca aatccagaaa caaaaccagc      720

gcggcctgat ccaattgata tggatgagga tgaacttgag atgctttctg aagccagagc      780

ccgcttggct aatactcagg gaaagaaggc caagaggaaa gcaagagaga aacaattgga      840

agaagcaaga cgtcttgctg ccctccaaaa aagaagagaa cttcgagcag ctggcataga      900

aattcagaag aaaagaaaaa ggaagagagg agttgattat aatgccgaaa tcccatttga      960

aaaaaagcct gcccttggtt tttatgatac ttctgaggaa aactaccaag ctcttgacgc     1020

agatttcagg aaattaagac aacaggatct tgatggggag ctaagatctg aaaaagaagg     1080

aagagataga aaaaaagaca aacagcattt gaaaaggaaa aaagaatctg atttaccatc     1140

agctattctt caaactagtg gtgtttctga atttactaaa aagagaagca aactagtact     1200

tcctgcccct cagatttcag atgcagaact ccaggaagtt gtaaaagtag gccaagcgag     1260

tgaaattgca cgtcaaactg ccgaggaatc tggcataaca aattctgctt ccagtacact     1320

tttgtctgag tacaatgtca ccaacaacag cgttgctctt agaacaccac gaacaccagc     1380

ttcccaggac agaattctgc aggaagccca gaacctcatg gccctcacca atgtggacac     1440

cccattgaaa ggtggactta ataccccatt gcatgagagt gacttctcag gtgtaactcc     1500

acagcgacaa gttgtacaga ctccaaacac agttctctct actccattca ggactccttc     1560

taatggagct gaagggctga ctccccggag tggaacaact cccaaaccag ttattaactc     1620

tactccgggt agaactcctc ttcgagacaa gttaaacatt aatcccgagg atggaatggc     1680

agactatagt gatccctctt acgtgaagca gatggaaaga gaatcccgag aacatctccg     1740

tttagggttg ttgggccttc ctgcccctaa gaatgatttt gaaattgttc taccagaaaa     1800

tgccgagaag gagctggaag aacgtgaaat agatgatact tacattgaag atgctgctga     1860

tgtggatgct cgaaagcagg ccatacgaga tgcagagcgt gtaaaggaaa tgaaacgaat     1920

gcataaagct gtccagaaag atctgccaag accatcagaa gtaaatgaaa ctattctaag     1980

acccttaaat gtagaaccgc ctttaacaga tttacagaaa agtgaagaac taatcaaaaa     2040

agaaatgatc acaatgcttc attatgacct tctacatcac ccttatgaac catctggaaa     2100

taaaaaaggc aaaactgtag ggtttggtac caataattca gagcacatta cctatctgga     2160

acataatcct tatgaaaagt tctccaaaga agagctgaaa aaggcccagg atgttttggt     2220

gcaggagatg gaagtggtta aacaaggaat gagccatgga gagctctcaa gtgaagctta     2280

taaccaggtg tgggaagaat gctacagtca agttttatat cttcctgggc agagccgcta     2340

cacacgggcc aatctggcta gtaaaaagga cagaattgaa tcacttgaaa agaggctcga     2400

gataaacagg ggtcacatga cgacagaagc caagagggct gcaaagatgg aaaagaagat     2460

gaaaattttg cttgggggtt accagtctcg tgctatgggg ctcatgaaac agttgaatga     2520

cttatgggac caaattgaac aggctcactt ggagttacgc acttttgaag aactcaagaa     2580

acatgaagat tctgctattc cccggaggct agagtgtcta aaagaagacg ttcagcgaca     2640

acaagaaaga gaaaaggaac ttcaacatag atatgctgat ttgctgctgg agaaagagac     2700

tttaaagtca aaattctgaa gtacagttta tattctgtca caggattaat taattgccgg     2760

ttttcatact ctagaaggct gaaactgatg tttatcttca ttgacaaatt tacccaccat     2820

ctgtggtttt tcagttgttt attttaaatg atatcgatct tacacattct gtgtataaag     2880

accttaactc cacaggacgg acattttaga gtttaaatta ttaaggctat cattctttta     2940

gtaatgtcat atttgcaaac ttttttagtt ttggccttta atttaaaaag cctaatttta     3000

aagtgctgcc tgtgagtaac tcttgaataa aaacaaaata taaaaaattg agaatgtagc     3060

cttttgtttg aagtaattag atacttaaga gtgcctgcaa accagcagct atgtactctg     3120

tgtcatattt aatgagtaac tcttgggtaa tcaaaatggt gatgcagtat cttaaacact     3180

taagaggcag ttctttgtgg ctttgttagt ttcagcaaag agtggtcatt tctgtataca     3240

ctgacaagtt agattaactt tttagtacct caaatttttt ttttgttaat atcactttaa     3300

agaaggtctc ttgtctgcca gctacttaaa taatttatgg gtcagggctt aaaagattta     3360

acttccttgc cccattattt tcttataagt attttttgac aaaggcattt taaaagttaa     3420

tttcaagaag gccatcaaac ttaaagctct atgtttagcc taagaagtca gttacatcag     3480

tgtagaattt ggggaatgga tagaggtgga gatatttaat tttatataat tcatataaat     3540

tgatttagtt acagtatcag ttggctacaa gctcattata gactagcaat gttttgacat     3600

caccaaaaac gtttgcccag tcttagaata ctagggacta taggaaggga agggattcat     3660

tcattcattc gatattgaat gtataccctg tgccagagtc ttagagagag aacaacaaac     3720

aaaataggcc tagttcttgt ttagtagagc ttatagtctt ttgagaatga cagacaatta     3780

aaatccaaat gtttatttgg tgattcttat gtgtcagaca cttaagtgtt gggagataag     3840

cagttattaa gacagagttc ttgctctcat ggaggtgaca ttagtgggga ggagatacta     3900

agtatgtcca gggaaagtat cagaccatga gttttagatt ctgtggagga aattaaagta     3960

gggtgattat gagatagtga atgagtggct attttagact ggacgatcaa agagacctct     4020

tggaaggcag ctatgctcac cactatacca ctgcactgtg ccgcaccgta ccactataag     4080

ctgcacggcc aaagagacct cttaaagaag taacatttaa gataacatgt gattgacatt     4140

ttagaatggg ctatccttgt gagattcaag gaaagaacat cctaggtgga gtgaatagca     4200

aacataaagc ctcttttgta tgtttgagga acaaaaagga caatgcagct agagtgtcaa     4260

gaatggcatt tctgtatata agacctcgtt gtatagagcc acataaataa ggctataata     4320

aggaatttgg atcttacttt aaatatgata agaatcgatg agaagatcta agcaaaggaa     4380

tgacatgatc agatttggtt ttagaaacat cactatctcc ttagtgtgta aaatctcacc     4440

aggctggaga tagggaagcc agtccaatta ggagcctgat gcagtgatcc agacaaaaaa     4500

ataatagtga ttctaactag agtccaggta atagtagtgg agatatgtgg agagacatga     4560

taggtatata cttaatagtc ttatcagacg ataaattgat attttcctgg tgtgtagtca     4620

cttaattcaa atactttttt cagtaagttc tgggttttct aggaaaaact tcagtatcat     4680

cagtgaataa tgatagtgtt tcttctgata gttttatttc acttttattg catgttttgt     4740

tatctgaaat gtttaggaca atgttaacaa taatgatgtt agacattttt ttttcttatt     4800

ttaatgggaa tgtccatagt tttaagtttg ctgttgggag ttagatagtc tttatctgaa     4860

agacagtgtc tctcttttag tttttaaaga gtttgaatta gaaatggctc tggaacttta     4920

aacagtatac catttgggca tctattaaag cattcatata attgttctca tttgatgttt     4980

tgatgaggta tattaataga ttttcccaca ttaaatcatc tttgcactcc tggaatcagg     5040

tagattaatt tttaaaagaa attttaaagg atttatagtt tatttgcact ttttgtagac     5100

ttgaattata tggatttaaa agttgatcta atattaataa aggctcactt tgttttcaaa     5160

atttgaagta attcacatac ttatagccta aaaaaatcgg caggaattac aaaatttcaa     5220

aactggcaca ttgtaaactg catatgcatt tgccaggtag tggtgccact tgaaatggtg     5280

aacagacaca ctgttatcct ttgtcagtat cctgtaaagc ccaggattct ttaccagcac     5340

catacagcga ttttggtgac tattttaaca ttcacactga ggccaggggt ggtgagtcat     5400

gcctgtaatc ctagcacttt gggaggccaa ggtgggagga tcatttgagc tcaggagttc     5460

aagattagcc tgggtaacat agtgagaccc tgtctctatt aaaaaataat aataaaaata     5520

acattcacat tggtattgtt cactaaggta ttggttgtta aggcattcat taaggtattg     5580

ttaaaacttg tgttaagcat gttaaagtct cagtaacttt gggatagaaa taaaatgtga     5640

taaaaagctg aaagaaacca ccacaaggga gagtcctttt tgaaatatta gagacataat     5700

gctgtctaat aaaaaacgac atcaaagaaa aactacacta cagtgactgc agacttaatg     5760

ttggccaacc atgcatcctc cctagaaatg catttgaatt tgatttacta atcttttatt     5820

taggaaattt acatttttac attagtgaga ttggtctttt gggctattgt actttttttt     5880

tttttttttt gagatggagt cttgctctct cacccaggct ggagtgcagt agtgcaatct     5940

tggcccactg caacctctgc ctcctgggct cgagtgattc tctgcctcag ccttccaagt     6000

agctgggact acaggcatgt gccaccgcac ctggctaatt tttgtgtttt tagtagagat     6060

ggggttttgc tatgttggcc aggctggtct tgaattcctg acctcaggtg atccacctac     6120

ctcggcctcc caaagtgcta gaattacagg tgtgagccac catgcccagc ctggttattg     6180

tattttgata ttgggatttt gctagctctc taaagtaaat aggataactg tatatctttt     6240

tctgtgcatt aagcagttat aacatgggaa tgatttgttc atgaaaggtt gaaagtctgt     6300

acttacagaa cttttgagtt cacagtgctt tctggaaata atttctttat aactgtcagt     6360

ttcttttgtg actattatgt tacctatttt taaatttaag caactttaaa ttaaaaaaat     6420

tgtttttaaa at                                                         6432


<210>  2345
<211>  7333
<212>  DNA
<213>  homo sapiens

<400>  2345
ggcggcggcg gcggcgcgga ctgggtgcgc ggcgcagcgt cctgtgttgg aatgtgcggc       60

tgccgcgagc tcgcggcgca gcagcggagc gagcgccgcc gaggcccggg gccccagacc      120

ctggcggcgg ctgccgcagc cgagacggca gggcgaggcc cggaggcctg agcaccctct      180

gcagccccac tcctgggcct tcttggtcca cgacggcccc agcacccaac tttaccaccc      240

tcccccacct ctcccccgaa actccagcaa caaagaaaag tagtcggaga aggagcggcg      300

actcagggtc gcccgcccct cctcaccgag gaaggccgaa tacagttatg gccacccagg      360

taatggggca gtcttctgga ggaggagggc tgtttaccag cagtggcaac attggaatgg      420

ccctgcctaa cgacatgtat gacttgcatg acctttccaa agctgaactg gccgcacctc      480

agcttattat gctggcaaat gtggccttaa ctggggaagt aaatggcagc tgctgtgatt      540

acctggtcgg tgaagaaaga cagatggcag aactgatgcc ggttggggat aacaactttt      600

cagatagtga agaaggagaa ggacttgaag agtctgctga tataaaaggt gaacctcatg      660

gactggaaaa catggaactg agaagtttgg aactcagcgt cgtagaacct cagcctgtat      720

ttgaggcatc aggtgctcca gatatttaca gttcaaataa agatcttccc cctgaaacac      780

ctggagcgga ggacaaaggc aagagctcga agaccaaacc ctttcgctgt aagccatgcc      840

aatatgaagc agaatctgaa gaacagtttg tgcatcacat cagagttcac agtgctaaga      900

aattttttgt ggaagagagt gcagagaagc aggcaaaagc cagggaatct ggctcttcca      960

ctgcagaaga gggagatttc tccaagggcc ccattcgctg tgaccgctgc ggctacaata     1020

ctaatcgata tgatcactat acagcacacc tgaaacacca caccagagct ggggataatg     1080

agcgagtcta caagtgtatc atttgcacat acacaacagt gagcgagtat cactggagga     1140

aacatttaag aaaccatttt ccaaggaaag tatacacatg tggaaaatgc aactattttt     1200

cagacagaaa aaacaattat gttcagcatg ttagaactca tacaggagaa cgcccatata     1260

aatgtgaact ttgtccttac tcaagttctc agaagactca tctaactaga catatgcgta     1320

ctcattcagg tgagaagcca tttaaatgtg atcagtgcag ttatgtggcc tctaatcaac     1380

atgaagtaac ccgccatgca agacaggttc acaatgggcc taaacctctt aattgcccac     1440

actgtgatta caaaacagca gatagaagca acttcaaaaa acatgtagag ctacatgtga     1500

acccacggca gttcaattgc cctgtatgtg actatgcagc ttccaagaag tgtaatctac     1560

agtatcactt caaatctaag catcctactt gtcctaataa aacaatggat gtctcaaaag     1620

tgaaactaaa gaaaaccaaa aaacgagagg ctgacttgcc tgataatatt accaatgaaa     1680

aaacagaaat agaacaaaca aaaataaaag gggatgtggc tggaaagaaa aatgaaaagt     1740

ccgtcaaagc agagaaaaga gatgtctcaa aagagaaaaa gccttctaat aatgtgtcag     1800

tgatccaggt gactaccaga actcgaaaat cagtaacaga ggtgaaagag atggatgtgc     1860

atacaggaag caattcagaa aaattcagta aaactaagaa aagcaaaagg aagctggaag     1920

ttgacagcca ttctttacat ggtcctgtga atgatgagga atcttcaaca aaaaagaaaa     1980

agaaggtaga aagcaaatcc aaaaataata gtcaggaagt gccaaagggt gacagcaaag     2040

tggaggagaa taaaaagcaa aatacttgca tgaaaaaaag tacaaagaag aaaactctga     2100

aaaataaatc aagtaagaaa agcagtaagc ctcctcagaa ggaacctgtt gagaagggat     2160

ctgctcagat ggaccctcct cagatggggc ctgctcccac agaggcggtt cagaaggggc     2220

ccgttcaggt ggagccgcca cctcccatgg agcatgctca gatggagggt gcccagatac     2280

ggcctgctcc tgacgagcct gttcagatgg aggtggttca ggaggggcct gctcagaagg     2340

agctgctgcc tcccgtggag cctgctcaga tggtgggtgc ccaaattgta cttgctcaca     2400

tggagctgcc tcctcccatg gagactgctc agacggaggt tgcccaaatg gggcctgctc     2460

ccatggaacc tgctcagatg gaggttgccc aggtagaatc tgctcccatg caggtggtcc     2520

agaaggagcc tgttcagatg gagctgtctc ctcccatgga ggtggtccag aaggagcctg     2580

ttcagataga gctgtctcct cccatggagg tggtccagaa ggaacctgtt aagatagagc     2640

tgtctcctcc catagaggtg gtccagaagg agcctgttca gatggagttg tctcctccca     2700

tgggggtggt tcagaaggag cctgctcaga gggagccacc tcctcccaga gagcctcccc     2760

ttcacatgga gccaatttcc aaaaagcctc ctctccgaaa agataaaaag gaaaagtcta     2820

acatgcagag tgaaagggca cggaaggagc aagtccttat tgaagttggc ttagtgcctg     2880

ttaaagatag ctggcttcta aaggaaagtg taagcacaga ggatctctca ccaccatcac     2940

caccactgcc aaaggaaaat ttaagagaag aggcatcagg agaccaaaaa ttactcaaca     3000

caggtgaagg aaataaagaa gcccctcttc agaaagtagg agcagaagag gcagatgaga     3060

gcctacctgg tcttgctgct aatatcaacg aatctaccca tatttcatcc tctggacaaa     3120

acttgaatac gccagagggt gaaactttaa atggtaaaca tcagactgac agtatagttt     3180

gtgaaatgaa aatggacact gatcagaaca caagagagaa tctcactggt ataaattcaa     3240

cagttgaaga accagtttca ccaatgcttc ccccttcagc agtagaagaa cgtgaagcag     3300

tgtccaaaac tgcactggca tcacctcctg ctacaatggc agcaaatgag tctcaggaaa     3360

ttgatgaaga tgaaggcatc cacagccatg aaggaagtga cctaagtgac aacatgtcag     3420

agggtagtga tgattctgga ttgcatgggg ctcggccagt tccacaagaa tctagcagaa     3480

aaaatgcaaa ggaagccttg gcagtcaaag cggctaaggg agattttgtt tgtatcttct     3540

gtgatcgttc tttcagaaag ggaaaagatt acagcaaaca cctcaatcgc catttggtta     3600

atgtgtacta tcttgaagaa gcagctcaag ggcaggagta atgaaacttt gaacaaggtt     3660

tcagttctta gtttgtaagg tatattacat tttatattca tttatgatag cagacaacct     3720

tttaagattg ctttaattag tatctgatgt tgatttttaa gtggcattct tttccttagg     3780

actttttatg tatacctgtt gattgttgtg taaattttag taaatctaag agagtgtact     3840

aaaccagcag gtatctgtta gcttatgtgt ttaattgaaa ttagaaggct aagatggtat     3900

aacagcattt tattgctttg tccagctaca acttgtcatt tttttctcca tgtcttatct     3960

tcctgtttca ctttagttta ttcttcgttt tttattgaga tctataaaaa attggcttac     4020

ttaatagcaa attacttgaa gaatttgcct gctttatata aagttagcac tttaagattt     4080

ttttttttag agatgagaag acatttaaat tgaagaaaaa ttcccccagc aatagacagt     4140

ctatcagtcc aagtatttac ttcctgagtt ttgatcaata ttttttattt gtgtatgtta     4200

atcgtcataa aaacagtgat tttggtgtgt tttttatttt ggtgctttaa tggcttaaga     4260

tgttgcacat tttttttttc ttttggtttc tgtttatgtt tttttgccta tgcagttaaa     4320

tttttcctag aaatagcatt tgtgttgaac agtaacactt tatacatata tatatgcatg     4380

tttattttgt ttggcgtctt tggagggatg cttttagact tgtttgcaaa agggcagttt     4440

tctttttctt tgctgcagtt gtctattttg cagaataata gtgtgtgcaa gtttgtgagc     4500

aaatgaaata tgcaggttca atctattgat tttgattttt acatcttata tctatgccag     4560

aatctgtatt tcatataact tatttatttc gaatggatgt agtaaattca cagctatcag     4620

ttttgatttt gcaataaata aaccactagg ttgcatgtcg aacaaatttt tatctcaaat     4680

accaaccatc agtttttttt ttcatgtgtt ttggtacagc taattcctaa ttgtagagtg     4740

ttaaatgttt gaggagaacc ttttctcata gatggttggt gttcatatgg ctactttaca     4800

ataaagagaa ctgtaagtga tatttggaaa ctacaaacct ggaattagga gatataatta     4860

ttccttcaag ttttatagaa tatcacttgg gagattccaa agccatagct attacgcggc     4920

aaacctagga taagaaaggt agtatgagtg ctggtagacc agctgcaact ttcctataca     4980

gtgaaaaagg ctggtgaaac aagtacagtc cagatttttt aaaatcatac tttctcaggg     5040

atctccacaa actggtgggt gtcctggctg tctgtgtgat agcctctttc tataggtgag     5100

gcctcaaatg aattgcagct atcctggtgt tcctatgagg gcactttgta tgaaaaaggg     5160

catgtactcc aaaacatttt tgtaggttct ttggccagtt gccaaagagt gtgaaagaat     5220

ccaatagagg atttttctta ctgatagcag tcattcattg cagtaaaata aaatatgatc     5280

ccattaggga atcttgaatt ctgacctccc atactccgtt ttgaaataac cactttatat     5340

ttcatttttt aaaaatctga tgatctcttt gaggcaggtt tcagatttgg cagtacaaca     5400

tgaaagatta ggaaaagcat taataacgtg tgggtggaaa gcttgttaaa aatctgagag     5460

tgaagtttga gttaaaagtt gtttgaacat ggcattgact gggaggccaa agatttaaag     5520

aagcggaaga ttcttctctt aagacatgag gagtaagttg tgtgataatg gtatgtgttt     5580

tgtgtgcatg aatggacatt gtaaatgttg aattctaggc tccgacaatc attgtcaaca     5640

gaagatcaag ctgcaaatat ttatgtttta aaacttaaat tataaagcta gttaagtctt     5700

tctaatgact agttttaatg ttcatgggta cattttacct aagttaccgt ttacattgta     5760

tagaaaaaga tacatcttaa gcacagattg gttattagga attagtttgg ggaagaggtt     5820

tttttgtgga ttctttcata ctgcaaagaa aaaccatttg ccttttgggg aattgagcta     5880

acttctaatc tagtcttaag actagaatgc taaaaacaaa aacatgaagg aaattaaaac     5940

cccttattat taaattgatt tgtaaaaaca ttgttactgg aaatttattg gacttgaggc     6000

cttcctccag aaaataagga cttgattgtc aggcctatat taggttctga accttaatgc     6060

catgtatttg tacttactaa aaattgtttc aatgaaaagt acattagcag tatgaacttc     6120

tggtccagtt ggaagttttt ccatttgaaa aatgtgatgt ttgcatggaa ctgtttgaaa     6180

cttttttatt ttctagtccc cctcccccac actggataga atttagccta gaattttccc     6240

tttggataaa agaacaaaaa ttgaacatgt tatttgtaaa ttgatgttta gtaattagtg     6300

ataaacttga aatactagca tatattataa gccttaatct taggtagtct tatgaaaatg     6360

aatctcttaa ctatcttttg aacctgtatt cacattggtt ttcaagatat tttaagttat     6420

attttttcct cttttcagag ctgcttctta ttctggggct actttttttt ttagttgtgt     6480

aattcacaaa gggctgcatt tttttttttt tttaataagg cttataacta tggctggatc     6540

ttttgctcta gtcttctaag aagggccatt ttatttttta gagtcacttc taaagtcatg     6600

tggtaattaa ctttggagac tgttttgcgt atgagtgctg atacaaatta aaacccaagt     6660

agacctcatt gcatgtcacc ctatgaatgt tgacaatgga aggaatacct tgcctgtagt     6720

atactgtcac ttctggattg ataagctgag gaagaaagtt aagtttcttt tttacataag     6780

tcagaaaaac ttacagctgg tgttcctagt ttcctggttg acctcagcag atgaagtgaa     6840

cagatagtgt taattcagat tgaagaaatt atctgaatct tggtttgtgt agatttacaa     6900

tctacatgca atattaacta aatcagatag cttttacagt ttcacatgtg tacataggtt     6960

ccctcccggt cccttccata tccattagtt attgaacttt ctaaactggc attgaaacat     7020

tacaacaatg ttttgttgca ccaattttat aaacttaagc agtgcaatac gtgttacttt     7080

tctgaggcaa accaaaggta aatttctcaa ggttcttgct gccttcttta gcagcatttg     7140

atggaagatc ttttatacat ttgtaataga taaaaataaa ccagattgca aatccttttt     7200

taaaatccta aaccatgtac caagtttttg gtccaaatta tgtaggataa gttaaactta     7260

aattgcattc tattaaccaa tatgagtgta tttctgtaag catagttatg ttgaaataaa     7320

gttttaaaaa cca                                                        7333


<210>  2346
<211>  4499
<212>  DNA
<213>  homo sapiens

<400>  2346
aggcagggcg cgggcagccc ggcgcggggt cctgggacgg gcgcggcgcg gggcgcgggc       60

ttctcggcgg ctgcggcccg ggcggcggcg atgctgtggc cgcggctggc ggcggccgag      120

tgggcggcgc tggcctggga gctgctgggc gcctcggtgc tgctgatcgc tgtgcggtgg      180

ctggtgcggc ggctgggccc gcggccggga ggtctgggcc gcagcgggac cccagttcct      240

ccgccaagcg cggccgccgc ccccgcctca ggtgaaatga caatggatgc tctgttggct      300

cgattgaaac ttctgaatcc agatgacctt agagaagaaa tcgtcaaagc cggattgaaa      360

tgtggaccca ttacatcaac tacaaggttc atttttgaga aaaaattggc tcaggcttta      420

ctggagcaag gaggaaggct gtcttctttc taccaccatg aggcaggtgt cacagctctc      480

agccaggacc cacaaaggat tttgaagcca gctgaaggga acccaactga tcaggctggt      540

ttttctgaag acagagattt tggttacagt gtgggcctga atcctccaga ggaggaagct      600

gtgacatcca agacctgctc ggtgccccct agtgacaccg acacctacag agctggagcg      660

actgcgtcta aggagccgcc cctgtactat ggggtgtgtc cagtgtatga ggacgtccca      720

gcgagaaatg aaaggatcta tgtttatgaa aataaaaagg aagcattgca agctgtcaag      780

atgatcaaag ggtcccgatt taaagctttt tctaccagag aagacgctga gaaatttgct      840

agaggaattt gtgattattt cccttctcca agcaaaacgt ccttaccact gtctcctgtg      900

aaaacagctc cactctttag caatgacagg ttgaaagatg gtttgtgctt gtcggaatca      960

gaaacagtca acaaagagcg agcgaacagt tacaaaaatc cccgcacgca ggacctcacc     1020

gccaagcttc ggaaagctgt ggagaaggga gaggaggaca ccttttctga ccttatctgg     1080

agcaaccccc ggtatctgat aggctcagga gacaacccca ctatcgtgca ggaagggtgc     1140

aggtacaacg tgatgcatgt tgctgccaaa gagaaccagg cttccatctg ccagctgact     1200

ctggacgtcc tggagaaccc tgacttcatg aggctgatgt accctgatga cgacgaggcc     1260

atgctgcaga agcgtatccg ttacgtggtg gacctgtacc tcaacacccc cgacaagatg     1320

ggctatgaca caccgttgca ttttgcttgt aagtttggaa atgcagatgt agtcaacgtg     1380

ctttcgtcac accatttgat tgtaaaaaac tcaaggaata aatatgataa aacacctgaa     1440

gatgtaattt gtgaaagaag caaaaataaa tctgtggaac tgaaggagcg gatcagagag     1500

tatttaaagg gccactacta cgtgcccctc ctgagagcgg aagagacttc ttctccagtc     1560

atcggggagc tgtggtcccc agaccagacg gctgaggcct ctcacgtcag ccgctatgga     1620

ggcagcccca gagacccggt actgaccctg agagccttcg cagggcccct gagtccagcc     1680

aaggcagaag attttcgcaa gctctggaaa actccacctc gagagaaagc aggcttcctt     1740

caccacgtca agaagtcgga cccggaaaga ggctttgaga gagtgggaag ggagctagct     1800

catgagctgg ggtatccctg ggttgaatac tgggaatttc tgggctgttt tgttgatctg     1860

tcttcccagg aaggcctgca aagactagaa gaatatctca cacagcagga aataggcaaa     1920

aaggctcaac aagaaacagg agaacgggaa gcctcctgcc gagataaagc caccacgtct     1980

ggcagcaatt ccatttccgt gagggcgttt ctagatgaag atgacatgag cttggaagaa     2040

ataaaaaatc ggcaaaatgc agctcgaaat aacagcccgc ccacagtcgg tgcttttgga     2100

catacgaggt gcagcgcctt ccccttggag caggaggcag acctcataga agccgccgag     2160

ccgggaggtc cacacagcag cagaaatggg ctctgccatc ctctgaatca cagcaggacc     2220

ctggcgggca agagaccaaa ggccccccgt ggggaggaag cccatctgcc acctgtctcg     2280

gatttgactg ttgagtttga taaactgaat ttgcaaaata taggacgtag cgtttccaag     2340

acaccagatg aaagtacaaa aactaaagat cagatcctga cttcaagaat caatgcagta     2400

gaaagagact tgttagagcc ttctcccgca gaccaactcg ggaatggcca caggaggaca     2460

gaaagtgaaa tgtcagccag gatcgctaaa atgtccttga gtcccagcag ccccaggcac     2520

gaggatcagc tcgaggtcac cagggaaccg gccaggcggc tcttcctttt tggagaggag     2580

ccatcaaaac tcgatcagga tgttttggcc gctcttgaat gtgcagacgt cgacccccat     2640

cagttcccgg ccgtgcacag atggaagagt gctgtcctgt gctactcacc ctcggacaga     2700

cagagttggc ccagtcccgc ggtgaaagga aggttcaagt ctcagctgcc agatctcagt     2760

ggccctcaca gctacagtcc ggggagaaac agcgtggctg gaagcaaccc cgcaaagcca     2820

ggcctgggca gtcctgggcg ctacagcccc gtgcacggga gccagctccg caggatggcg     2880

cgcctggctg agcttgccgc cctgtaggct tggcgctggg ctctcggttt gttcttcatt     2940

tttaaagaag gaagggtcat atgtttattg ctaaactgtc aaaaaggaat atattctgat     3000

taaattatta ctcctcactt tgagggtgtg agaattttag aagatttaaa tgttctatat     3060

aacacttaga tttctgatat tttggaagaa gttagaagtt aatgaaagca aactcagtta     3120

ccaattttct ggaaaatatc catgtggtaa tggtagactt tttaggtggc aatttctagg     3180

tctgaaatat agcagaggaa agggcgctga ggcagttgca ggcaggcagc cctgtactta     3240

ccctgtactc acctcatccg acagacgctg tggatgagga ggggcttggc ggaggcgtga     3300

gcaccgatgt ccctttgata acctgcactc accaagatga actatttgcc gccctgtctt     3360

ttcctgggtt ggggggtggc atctgatggt ggcagagtgc ctgttggttc gcccgtgggt     3420

ctcatggttc agacagaggg aggtggacgg cagggatcag ggagccagga gcgcgcctca     3480

gacttgcagc aaccattgtg atttgggttg ttcggaatat ttaaattact gatcagaaga     3540

tgaaagtagc ttttctcttg ggaagtcttg cagcccgtgg gagtgatacc aggagcaaca     3600

cagagctcag cagcggcgcc aaggtgttcc ctgtttcctc agcacgtgag ccttcaccgc     3660

ctgcttcatt caggagccag tgcagcagta atacagtcta tacattgttc tgttttcaaa     3720

tttatcctga ggctttgttg agcataaatg attatacgat aaaggtatcc gttattttgg     3780

aactcatttc agttgggatc tcctgtatgc agagtgttgc atttagaggt ttgagtccca     3840

tcttggtttc ttgccgtgct gactgtagcc ttcaccttga cttgaatgaa ggtctgtggt     3900

tggaatgtgt gaggagccgc tgaggtgttc aggaggtgct gcctggaggt cggtttcttc     3960

ctgggtgtta cgggcaactg ctcacacagt tgtttctctg tgaacatttc cagtgtttaa     4020

tccaaaatga aaacccacca atgcttttgc taacttcagt gccttttata aatcattttt     4080

aaatttcctg aacttgcttt ttgaggatat acagggatat taagtagacg caggattgtt     4140

tttgtttgta aaaattctga attgaaactt tgttttaaaa aaaggcttct ttctttcata     4200

tgacaagaga taggtcagga atattggaat caagatttaa atgttaaaat tcgattttgt     4260

tacacagggt gtgttcattt gttttgtagc agacaagatc tagatcccag acagaaacaa     4320

cacatgctat tctaaaaagc cgcattttaa aaggcacctt ggttctcaaa agaaatcaga     4380

atatggatat tcgtagtgat gatctgtttt ctctaaaatc ttaccatatt gtctgtatat     4440

ggttgtaaat tcaaatggaa agtaaaacgt tttggccctg ataaaaaaaa aaaaaaaaa      4499


<210>  2347
<211>  9228
<212>  DNA
<213>  homo sapiens

<400>  2347
acaatgcttt gagccttacc gcatttcagt gggggaaaaa aagttaccta ggaggtctga       60

tttttcaaag aaatttgcat acatgcaaat gtgccgcccg gcctcctcct cggttctcta      120

cgtgcccacg cggtggcccg gggggtgcgg ggcaacctgg caaagttgcc caagtcctcc      180

accgagacgc acacgcatac cccagcgccc ggcagttatg tattctccgc tctgtctcac      240

ccaggatgaa tttcatcctt tcatcgaagc acttctgccc cacgtccgag cctttgccta      300

cacatggttc aacctgcagg cccgaaaacg aaaatacttc aaaaaacatg aaaagcgtat      360

gtcaaaagaa gaagagagag ccgtgaagga tgaattgcta agtgaaaaac cagaggtcaa      420

gcagaagtgg gcatctcgac ttctggcaaa gttgcggaaa gatatccgac ccgaatatcg      480

agaggatttt gttcttacag ttacagggaa aaaacctcca tgttgtgttc tttccaaccc      540

agaccagaaa ggcaagatgc gaagaattga ctgcctccgc caggcagata aagtctggag      600

gttggacctt gttatggtga ttttgtttaa aggtattccg ctggaaagta ctgatggcga      660

gcgccttgta aagtccccac aatgctctaa tccagggctc tgtgtccaac cccatcacat      720

aggggtttct gttaaggaac tcgatttata tttggcatac tttgtgcatg cagcagattc      780

aagtcaatct gaaagtccca gccagccaag tgacgctgac attaaggacc agccagaaaa      840

tggacatttg ggcttccagg acagttttgt cacatcaggt gtttttagtg tcactgagct      900

agtaagagtg tcacagacac caatagctgc aggaactggc ccaaattttt ctctctcaga      960

tttggaaagt tcttcatact acagcatgag tccaggagca atgaggaggt ctttacccag     1020

cacatcctct acgagctcca caaagcgcct caagtctgtg gaggatgaaa tggacagtcc     1080

tggtgaggag ccattttata caggccaagg gcgctcccca ggaagtggca gtcagtcaag     1140

tggatggcat gaagtggagc caggaatgcc atctccaacc acactgaaga agtcggagaa     1200

gtctggtttc agcagcccct ccccttcaca gacctcctcc ctgggaacgg cgttcacaca     1260

gcatcaccga cctgtcatta caggacccag agcaagtccg catgcaacac catcgactct     1320

tcatttcccg acatcaccca ttatccagca gcctgggcct tacttctcac acccagccat     1380

ccgctatcac cctcaggaga cgctgaaaga atttgtccaa cttgtctgcc ctgatgctgg     1440

tcagcaggct ggacaggtgg ggttcctcaa tcccaatggg agcagccaag gcaaggtgca     1500

caacccattc cttcccaccc caatgttgcc accgccaccg ccaccaccga tggccaggcc     1560

tgtgcctctg ccggtgccag acacaaagcc tccaaccacg tcaacagaag gaggtgcagc     1620

ctcccccacg tcaccaacct actcgacacc cagcacctcc cccgcaaacc gattcgtcag     1680

tgttggacca cgggatccaa gctttgtaaa tatccctcaa cagacacagt cctggtacct     1740

gggataaaag ttgcagcgtc ccaccatcca ccagacagac cacctgaccc cttctcaact     1800

ctgtaacatg gacgcaacct caacccagcg cagttacaac ttcactatca gcggaagggg     1860

agaaaaaccg attcaaatca acttgtacat ggaaacagca agcattatgg tcaaacagca     1920

aaggccataa ccttttggga tttttttttt tttaaaatac tttagggact gttgtaattt     1980

ctcatatggt gctggaaatg gttgggcttt gtaacatttg aagtgtttcc atggtagcgt     2040

gagcattagg tgacgtggct agcggaggac tacccttgct cactgacttc ctgttgtaac     2100

acactttcct tacggagcct ggctgtttca cagtatttca tgaatttacc cacacaggtg     2160

tgatcctcct tgagcattga ggaggcacat ggagaactaa atcttttgta gtagctgaga     2220

tctgcaatat ataacgggac agtcaaaggg caatgttttt ctgtaacata ttggaaaaag     2280

aaaatgcagt tatattcctt ttttatttgt tcctttagtt tgttttggtt cagcagtcag     2340

cagttaagta tataacatgg cccgcaagga caatgaatcc actcacattg cagaacaatt     2400

ccgaaaatgg caaactacta ctactactgt tcagtttttt aaaagttttg aaatgctgca     2460

cttacattta aaaaaacaac aacaacattt tttcaacaat ttcaacaatg acacaaaaat     2520

tcacatggaa atggggaaga tggtctgttt tgacagaaac tgacaggaat caatcaaaac     2580

aatcgaattt tgaattgagt aaagtgcaat ttcattggat agctaaatat ctttgtaaga     2640

tagagattgt tgaaaattct atttttgttt ttctagtcct ttcaccccag gactctaaat     2700

tattggggta aaaaacagcc ttgcaagaaa aaggggagct atttttgctt tttatgtttt     2760

ttattgttaa acttgtatcc ctttaaaaac tgaaggaaat taaaaaaaaa aaacaaaaaa     2820

acaaatctaa tggtgctttt accacaatat gttaactaca ttaaatgcta attaattatt     2880

ttctgttatc aaagcacatg actaaaatga aatcatggta tctgttaatt ttataagcta     2940

gaagtcacta taatggatta cgccaattct aaaaaatttt acacctatct ggcatcatag     3000

gatttatcag ttatcagaca cctcattgta ccagagattg tccagaagtt ttaaagacct     3060

ttgcatccct gaactgggct atgggaaata ataatagtaa taataataat aataataatg     3120

atgaaaccaa tactgacaca aatgctggtg cccattcaga tcaagggtac ttgttaggga     3180

aaaaaaaaaa agtttgcacc cccaaacgtc ctgtatctta tgaaaaaaaa aacaaaaaac     3240

aaaaacaaaa aaaaaacaca aaaaaccaca gaaacaaaaa caaaaaaaag tgcaagtgat     3300

ttttctacca gacagcgaag cacccctttg cttcccatgc gacttcaaga aggtttccta     3360

tactatacat atatatacgt tctggttggc aagccctgct gatcagagaa agtctctgca     3420

tgttctagtg ttagtaacta atttttatat agttaatgta ggataaagta gagtgcatta     3480

agacacaata ttgtaatccc tactctaggc acttgccttt aaactatgtt tttcagccct     3540

tcagaagggt tctactactg tcctatacaa tcaagtaact gaaattcttg ggaagacact     3600

ttgctcctca tctttctccc cgaaacaatg ttgttttgtt ttgttttttt tccttaattt     3660

gcacgaaaac aaaaattcca tatcaatgtg ccttgccctg gatagcgatt atttgtggaa     3720

ttgttgcaca tgctcctcta ttgaaagggg tttttcccta gtcaagcatt tggagacact     3780

ttttgtaaat gtgactttta tgtcagccat cgtcagtttc aacatctaga actaaataga     3840

aagctagttg ttccgcagat aggagtagtc tttattgtcc tgtacggtcg gtggcagtgc     3900

tattctgaga tctgtagatg cttagaatat cagtattttg gatgttgctg cattttacaa     3960

tttatttgga gtcttccttt attttccccc agatatatga aaatatgcaa tacctgctta     4020

tatcatgtag aaaagcttag caattattaa tttttctttt attttttttt atttgaccaa     4080

agtcggtgct gcacttgacg cagtgtgttt taggtgtttg tctttgtact tttttgtgat     4140

ttttgaatgc acgtgcgcag gaagggctcc tcttagagaa gcagtcaaac tgtgaagcac     4200

taagctgacc ctgcttcaag caattttgtt tttacaactg ttcctttcac aagcaagcct     4260

taaaaaaaaa aaagacaact tcctttttct tcagctccca caccccattt ttcttagcag     4320

actgcagtca atccacattc aataaaaagt atataatgcc catttttata tgcacgtttt     4380

taaacttcca agttctgaaa attgtttact ggttatctct atttaaggaa aaaaaaataa     4440

aataaaacat tttggatttt catatgtgtc tgataagtgg ttgaatagtc gtttggcgct     4500

gttgtatggt gtgattgtca gtgtatggtg tcacttccta tagccagcca gcatactttg     4560

ccttccccta tagcacttag ctgggcatta ctttattatg acatatgtgc actaaaaaat     4620

gaaaaaaagg aaaaaaagaa aaaaaaaaag aaaaaatagc agctttcagt gcttcacagt     4680

gaagggaaaa aagcctagac aaacattttg tcagaacctt gcaataagcc aaggtattac     4740

cagtaaattg gttgtatata caataaaatt gcaccctttt ttaaacaaaa caaactaagc     4800

aatagtttgg gcagttttag ttgtttttag tgagcatgtt gtagtcatga ctgcaaagag     4860

agagaataaa ctgcccgctc agaagatatg taatttgtat tgttgtatag ttttattgat     4920

tacactgatt tattctaccc tattttataa tgcaggactt ttgtaatgtt gtttaaatga     4980

ggaaaaattt ctgtcaaatt agcctagtaa aatttctgat cgttcattat aaaggcagcg     5040

ttcatagaat tgcttttctt tctttttacc ccccctttgg gaactggatt taagtttaaa     5100

actttcctgt ttcctttttt tttttttttt tgtaagtatt taaatacaat tatttttttc     5160

tctcaatggt atagcatatt cctatgcttg agaagtatag gtctactgaa aaaccattgt     5220

aaatggacgt tacaggtatg ctgtattttt gaaggtattt tgttgtatta agtttgatga     5280

agctaaaatt agggaactct gaacagattt gcaggaaaaa atgttttaaa ggctttaaaa     5340

cattagggag gcagtctagg gtgataacga acaggggtta agtattaaat acacgaagtt     5400

acatttttgt tcatgtttca ttgtccagaa agcagcagga aactattcag ttgtgatcaa     5460

gcaggaaaaa agaaacacca acagttgcca gtgtttttgc tttttagctt aaaagcatag     5520

tgaagatgct tgaggaagac tttgctacct ggggtgtgta gacagacaga ctgagagcta     5580

tcagcatttg aaggcccagc ccttgactct gagacacatt tgaatttttt ctttcccatc     5640

aaatggcatt aacaagattg ggcaaagatg agtccctcaa atttctgtgt tttttgtttg     5700

tttgtttgtt tgttttttct ttgggaactg aagtcagagg cacgaacact aactcttagc     5760

atttttctgt agactttttc ttctggccct tgtccctgcc agcaaaacgc cccttttctg     5820

atcattcgtg cgcagagggc ctcccagtaa tgccacgctc tccatgctag agagccttct     5880

ctttcctctg aggtttgaac tgatgttctg tgtcttcaca ccctggcatg acagttacgt     5940

gtggtcagcc cgctccccag gcccgtccct gccgccgcca ggtgtgggct ctaggcaggc     6000

cgacaaggtt acacctccca gagcttgtga tcttcatttt ctgacagtca aagtgtgaag     6060

gaacccagac ttccccgagc cacggtgttc agtcagccca caggaatatg caagacccat     6120

ctccaaaagt ttgtctttga ttttttccaa gcccttagcc ccataagctt tgaatcctgt     6180

agttacagtg gcataaagga ctgacaaaac ctggataagg aaaaaccttt tttttctatg     6240

aatttttttt gttttttagg ggaaagggat tctaagaatg tcatttaatg tactttgcat     6300

catgtctcta gaaatatctt tgtccatagt ggtggtggag tctctctctc tctctctctt     6360

tttgtttgct tctgttttct ttcttgtctt cattctttct tttctttttt atttctggta     6420

gcaggcctcc atagaacaaa tctaaaacac aaccaccata gtaatgtaag gagagcttca     6480

gtggcacctc aaaacccacc cttcgagatc tgtccaaaga cagtctcaga aagctgcact     6540

gcccaccggc tcagctttca ttcaaaaagg cttccaaggc caattctgtc ttgaagtcaa     6600

tgcatgtatt tactgtttga cagtaaaccc gctctgcctt ctccacgtcc aaggctgtgc     6660

attcgtctaa ttagcgtcgt gtatgttttc cttttatttt ttccaataaa aaagcagtgg     6720

gatgaaaatt gctttgatat atagcaggta acattgaagc tattccatag cacttaactg     6780

tagtgaatac tgtgtcacca attttgaaat caatttaatg tttaatgcaa atccattaca     6840

tggtgctatt ataggctgac aaaatgattt acacaaatgt gacaacttgg gctcaattca     6900

ctctgctttc caacagtgta aatgcatagc agtgtttatc tgcatgagaa ctatgcacta     6960

atctatctga agaaaaaaac tatatcaact ttggtatcta ctttccgttt acttcaatcc     7020

ttgccttttt ggtcattgtt ataatgccag ctttaggaca gaaagaatta taagaaaacc     7080

agcataatac ctgatatatt aaaatgtagt gcctgtgaaa tctgtattat attgctcttc     7140

tgaagtaaga tttttctaca ccggtagcct tcgctgtctg tcagtcagga ccttctggta     7200

taggtgatgt aaaataaccg tacaatatta atgcatgcga ttccataatg cttagtgaac     7260

tgtatgaata ttactcaaag ttatgttagt ctttttttcc gacttggttc ttgtcagcta     7320

ggtttaaagg tatttcactg agaacgcaaa ttctgtcttt tcttgatttc ggctgttttc     7380

agtattttgg aggtatacat ttacttaaat tcagtattac tcgtgttttg tttttgtttt     7440

tgttttttgt tttctttttc ctaggggaca agcatgggtg tttgatttca gaaatcagta     7500

cctggcgaga tttttgtctc aaaacgacta tttgaatttc aagaactgtg ctgcgaagac     7560

actctgagaa catttgcaag tcaggggcat tttccttgac ccttgactga tgctatgcgg     7620

agactgatac attttcttaa tggacaatgt tcaagccagg tacccatgct tgatctgtct     7680

tcacaccaga cctcctcata ttaaaaggaa aaataagaaa aaaaatgtaa gaaatcacat     7740

ggctatttag tttcatgcac agttgcaata ttttcttcaa aaataaaact ctgtacaaac     7800

tttgggcccg attcataaga aaaagaagtt tgctattaac acgggatttt tttaatatac     7860

tttttttggt ctaaatttga aattacttgc ttcccaaatt aaataaattt catctcattt     7920

ttttccctaa accagcaccc atctgccttt tattccccaa agagttacct ttcccagatt     7980

agggggatgg tatgtgggga gcagatagcg gaaatgctta gaaagataag ggggaccacc     8040

cacagctggt cgtgagaaca gggagacagt gtgtgggggt gggacctcat ctgtgtgcct     8100

ggtatcctga gttttacatg tagatgcatt cgcctatttg attcagaaaa ataaactttc     8160

ccaaaatgtg tctgaaccac aagagcatac agtggaagtg ctacctctaa tctaaccaga     8220

gcaccttcat ggtggaagac acccaccagg tcatacaatg tgaacttttg tatctctgca     8280

gtggtttcaa ggacaaatag tgtccaatgt attgggccat ttttcctgct gtttttatac     8340

tcaacttctc aaaatgaaaa aagcttttat ttttcctttg acttatttgt gttgttctta     8400

ttttttaaat ttttattttt tgataatagt ctgtaagtta gcctttttgg gttttttttt     8460

tttttttttg gctttttttt ttgtttgttt ttttttcttt tgacattgca accgaaggtc     8520

ataaggccgc tagctccgct gggacagagg cttgagagaa ctaacggctc ggtgccttct     8580

ccctggtctc agaccatcgt ctctgcactg cgaaggcatt tggtagcctc gccactgaga     8640

tactaactag acctagacta ggagctttat caggttctag gaggtccttt aggaagactc     8700

tcaaaggcaa atccctgatc ccccgcccca cccttagccc tgccctctca ccagagcaaa     8760

attcactggg gacttttccc accacacatg gaaatctgtc cactcggaat acctctgttt     8820

tccatttcaa attgtagggg gaggggatgg aacacttcca gtgatggtaa gagatctgtt     8880

atgaaacgaa acaccccccg tgttaataac ttggtctgaa atctgttttt atgagccggg     8940

ccccctgtgc ctctagtata cttgtattga ctctcatagt taccctttta gttttactgt     9000

gttctgtgaa aatttgtaat tggttgagaa tcactgtggg cgtccattct tattcaacta     9060

aatctccaca ggttttttga gctggtgtgg attagtttaa ctcttgtatt caaccattag     9120

tgctaccacc ttctcacatt acaatacaat tactggaagc aagtactgca tttcctatgc     9180

aacaaaaaag gaaaaataaa aaattgctaa tgctaaaaaa aaaaaaaa                  9228


<210>  2348
<211>  9403
<212>  DNA
<213>  homo sapiens

<400>  2348
ggccgcggag gctcgggacc cggctggccg cgcggcgccg cagccgcccc ctcccccaca       60

ccccctcccc cccgcggcgg cggcgcgagc gggcggcggc tgtgcggtgc ggtgcagagc      120

ggaggcggag gcgggcgcgc gggcagctcg cgggcacccg gccgggccgg cgcgggagcg      180

ggaaagggtg cgctatgcct ttaacacccg cgtacagtag gcatgtatag tggagtgtag      240

ggaaactcta ggcggggtta aagttcagct catggagcgg caatagcgct ggctggctgg      300

ctgcagttga gccgacttgg aaatgtgaac gcaagaagca ggcttgattt ttttttctcc      360

ccccttctct ctctctctct ctctctctct tcctctctcc ctctttctcc tctctcaccc      420

acactcacgc acacctccaa accgcacacc cagacgcaca cgcatacccc agcgcccggc      480

agttatgtat tctccgctct gtctcaccca ggatgaattt catcctttca tcgaagcact      540

tctgccccac gtccgagcct ttgcctacac atggttcaac ctgcaggccc gaaaacgaaa      600

atacttcaaa aaacatgaaa agcgtatgtc aaaagaagaa gagagagccg tgaaggatga      660

attgctaagt gaaaaaccag aggtcaagca gaagtgggca tctcgacttc tggcaaagtt      720

gcggaaagat atccgacccg aatatcgaga ggattttgtt cttacagtta cagggaaaaa      780

acctccatgt tgtgttcttt ccaacccaga ccagaaaggc aagatgcgaa gaattgactg      840

cctccgccag gcagataaag tctggaggtt ggaccttgtt atggtgattt tgtttaaagg      900

tattccgctg gaaagtactg atggcgagcg ccttgtaaag tccccacaat gctctaatcc      960

agggctctgt gtccaacccc atcacatagg ggtttctgtt aaggaactcg atttatattt     1020

ggcatacttt gtgcatgcag cagattcaag tcaatctgaa agtcccagcc agccaagtga     1080

cgctgacatt aaggaccagc cagaaaatgg acatttgggc ttccaggaca gttttgtcac     1140

atcaggtgtt tttagtgtca ctgagctagt aagagtgtca cagacaccaa tagctgcagg     1200

aactggccca aatttttctc tctcagattt ggaaagttct tcatactaca gcatgagtcc     1260

aggagcaatg aggaggtctt tacccagcac atcctctacg agctccacaa agcgcctcaa     1320

gtctgtggag gatgaaatgg acagtcctgg tgaggagcca ttttatacag gccaagggcg     1380

ctccccagga agtggcagtc agtcaagtgg atggcatgaa gtggagccag gaatgccatc     1440

tccaaccaca ctgaagaagt cggagaagtc tggtttcagc agcccctccc cttcacagac     1500

ctcctccctg ggaacggcgt tcacacagca tcaccgacct gtcattacag gacccagagc     1560

aagtccgcat gcaacaccat cgactcttca tttcccgaca tcacccatta tccagcagcc     1620

tgggccttac ttctcacacc cagccatccg ctatcaccct caggagacgc tgaaagaatt     1680

tgtccaactt gtctgccctg atgctggtca gcaggctgga caggtggggt tcctcaatcc     1740

caatgggagc agccaaggca aggtgcacaa cccattcctt cccaccccaa tgttgccacc     1800

gccaccgcca ccaccgatgg ccaggcctgt gcctctgccg gtgccagaca caaagcctcc     1860

aaccacgtca acagaaggag gtgcagcctc ccccacgtca ccaatcctgg tacctgggat     1920

aaaagttgca gcgtcccacc atccaccaga cagaccacct gaccccttct caactctgta     1980

acatggacgc aacctcaacc cagcgcagtt acaacttcac tatcagcgga aggggagaaa     2040

aaccgattca aatcaacttg tacatggaaa cagcaagcat tatggtcaaa cagcaaaggc     2100

cataaccttt tgggattttt ttttttttaa aatactttag ggactgttgt aatttctcat     2160

atggtgctgg aaatggttgg gctttgtaac atttgaagtg tttccatggt agcgtgagca     2220

ttaggtgacg tggctagcgg aggactaccc ttgctcactg acttcctgtt gtaacacact     2280

ttccttacgg agcctggctg tttcacagta tttcatgaat ttacccacac aggtgtgatc     2340

ctccttgagc attgaggagg cacatggaga actaaatctt ttgtagtagc tgagatctgc     2400

aatatataac gggacagtca aagggcaatg tttttctgta acatattgga aaaagaaaat     2460

gcagttatat tcctttttta tttgttcctt tagtttgttt tggttcagca gtcagcagtt     2520

aagtatataa catggcccgc aaggacaatg aatccactca cattgcagaa caattccgaa     2580

aatggcaaac tactactact actgttcagt tttttaaaag ttttgaaatg ctgcacttac     2640

atttaaaaaa acaacaacaa cattttttca acaatttcaa caatgacaca aaaattcaca     2700

tggaaatggg gaagatggtc tgttttgaca gaaactgaca ggaatcaatc aaaacaatcg     2760

aattttgaat tgagtaaagt gcaatttcat tggatagcta aatatctttg taagatagag     2820

attgttgaaa attctatttt tgtttttcta gtcctttcac cccaggactc taaattattg     2880

gggtaaaaaa cagccttgca agaaaaaggg gagctatttt tgctttttat gttttttatt     2940

gttaaacttg tatcccttta aaaactgaag gaaattaaaa aaaaaaaaca aaaaaacaaa     3000

tctaatggtg cttttaccac aatatgttaa ctacattaaa tgctaattaa ttattttctg     3060

ttatcaaagc acatgactaa aatgaaatca tggtatctgt taattttata agctagaagt     3120

cactataatg gattacgcca attctaaaaa attttacacc tatctggcat cataggattt     3180

atcagttatc agacacctca ttgtaccaga gattgtccag aagttttaaa gacctttgca     3240

tccctgaact gggctatggg aaataataat agtaataata ataataataa taatgatgaa     3300

accaatactg acacaaatgc tggtgcccat tcagatcaag ggtacttgtt agggaaaaaa     3360

aaaaaagttt gcacccccaa acgtcctgta tcttatgaaa aaaaaaacaa aaaacaaaaa     3420

caaaaaaaaa acacaaaaaa ccacagaaac aaaaacaaaa aaaagtgcaa gtgatttttc     3480

taccagacag cgaagcaccc ctttgcttcc catgcgactt caagaaggtt tcctatacta     3540

tacatatata tacgttctgg ttggcaagcc ctgctgatca gagaaagtct ctgcatgttc     3600

tagtgttagt aactaatttt tatatagtta atgtaggata aagtagagtg cattaagaca     3660

caatattgta atccctactc taggcacttg cctttaaact atgtttttca gcccttcaga     3720

agggttctac tactgtccta tacaatcaag taactgaaat tcttgggaag acactttgct     3780

cctcatcttt ctccccgaaa caatgttgtt ttgttttgtt ttttttcctt aatttgcacg     3840

aaaacaaaaa ttccatatca atgtgccttg ccctggatag cgattatttg tggaattgtt     3900

gcacatgctc ctctattgaa aggggttttt ccctagtcaa gcatttggag acactttttg     3960

taaatgtgac ttttatgtca gccatcgtca gtttcaacat ctagaactaa atagaaagct     4020

agttgttccg cagataggag tagtctttat tgtcctgtac ggtcggtggc agtgctattc     4080

tgagatctgt agatgcttag aatatcagta ttttggatgt tgctgcattt tacaatttat     4140

ttggagtctt cctttatttt cccccagata tatgaaaata tgcaatacct gcttatatca     4200

tgtagaaaag cttagcaatt attaattttt cttttatttt tttttatttg accaaagtcg     4260

gtgctgcact tgacgcagtg tgttttaggt gtttgtcttt gtactttttt gtgatttttg     4320

aatgcacgtg cgcaggaagg gctcctctta gagaagcagt caaactgtga agcactaagc     4380

tgaccctgct tcaagcaatt ttgtttttac aactgttcct ttcacaagca agccttaaaa     4440

aaaaaaaaga caacttcctt tttcttcagc tcccacaccc catttttctt agcagactgc     4500

agtcaatcca cattcaataa aaagtatata atgcccattt ttatatgcac gtttttaaac     4560

ttccaagttc tgaaaattgt ttactggtta tctctattta aggaaaaaaa aataaaataa     4620

aacattttgg attttcatat gtgtctgata agtggttgaa tagtcgtttg gcgctgttgt     4680

atggtgtgat tgtcagtgta tggtgtcact tcctatagcc agccagcata ctttgccttc     4740

ccctatagca cttagctggg cattacttta ttatgacata tgtgcactaa aaaatgaaaa     4800

aaaggaaaaa aagaaaaaaa aaaagaaaaa atagcagctt tcagtgcttc acagtgaagg     4860

gaaaaaagcc tagacaaaca ttttgtcaga accttgcaat aagccaaggt attaccagta     4920

aattggttgt atatacaata aaattgcacc cttttttaaa caaaacaaac taagcaatag     4980

tttgggcagt tttagttgtt tttagtgagc atgttgtagt catgactgca aagagagaga     5040

ataaactgcc cgctcagaag atatgtaatt tgtattgttg tatagtttta ttgattacac     5100

tgatttattc taccctattt tataatgcag gacttttgta atgttgttta aatgaggaaa     5160

aatttctgtc aaattagcct agtaaaattt ctgatcgttc attataaagg cagcgttcat     5220

agaattgctt ttctttcttt ttaccccccc tttgggaact ggatttaagt ttaaaacttt     5280

cctgtttcct tttttttttt ttttttgtaa gtatttaaat acaattattt ttttctctca     5340

atggtatagc atattcctat gcttgagaag tataggtcta ctgaaaaacc attgtaaatg     5400

gacgttacag gtatgctgta tttttgaagg tattttgttg tattaagttt gatgaagcta     5460

aaattaggga actctgaaca gatttgcagg aaaaaatgtt ttaaaggctt taaaacatta     5520

gggaggcagt ctagggtgat aacgaacagg ggttaagtat taaatacacg aagttacatt     5580

tttgttcatg tttcattgtc cagaaagcag caggaaacta ttcagttgtg atcaagcagg     5640

aaaaaagaaa caccaacagt tgccagtgtt tttgcttttt agcttaaaag catagtgaag     5700

atgcttgagg aagactttgc tacctggggt gtgtagacag acagactgag agctatcagc     5760

atttgaaggc ccagcccttg actctgagac acatttgaat tttttctttc ccatcaaatg     5820

gcattaacaa gattgggcaa agatgagtcc ctcaaatttc tgtgtttttt gtttgtttgt     5880

ttgtttgttt tttctttggg aactgaagtc agaggcacga acactaactc ttagcatttt     5940

tctgtagact ttttcttctg gcccttgtcc ctgccagcaa aacgcccctt ttctgatcat     6000

tcgtgcgcag agggcctccc agtaatgcca cgctctccat gctagagagc cttctctttc     6060

ctctgaggtt tgaactgatg ttctgtgtct tcacaccctg gcatgacagt tacgtgtggt     6120

cagcccgctc cccaggcccg tccctgccgc cgccaggtgt gggctctagg caggccgaca     6180

aggttacacc tcccagagct tgtgatcttc attttctgac agtcaaagtg tgaaggaacc     6240

cagacttccc cgagccacgg tgttcagtca gcccacagga atatgcaaga cccatctcca     6300

aaagtttgtc tttgattttt tccaagccct tagccccata agctttgaat cctgtagtta     6360

cagtggcata aaggactgac aaaacctgga taaggaaaaa cctttttttt ctatgaattt     6420

tttttgtttt ttaggggaaa gggattctaa gaatgtcatt taatgtactt tgcatcatgt     6480

ctctagaaat atctttgtcc atagtggtgg tggagtctct ctctctctct ctctttttgt     6540

ttgcttctgt tttctttctt gtcttcattc tttcttttct tttttatttc tggtagcagg     6600

cctccataga acaaatctaa aacacaacca ccatagtaat gtaaggagag cttcagtggc     6660

acctcaaaac ccacccttcg agatctgtcc aaagacagtc tcagaaagct gcactgccca     6720

ccggctcagc tttcattcaa aaaggcttcc aaggccaatt ctgtcttgaa gtcaatgcat     6780

gtatttactg tttgacagta aacccgctct gccttctcca cgtccaaggc tgtgcattcg     6840

tctaattagc gtcgtgtatg ttttcctttt attttttcca ataaaaaagc agtgggatga     6900

aaattgcttt gatatatagc aggtaacatt gaagctattc catagcactt aactgtagtg     6960

aatactgtgt caccaatttt gaaatcaatt taatgtttaa tgcaaatcca ttacatggtg     7020

ctattatagg ctgacaaaat gatttacaca aatgtgacaa cttgggctca attcactctg     7080

ctttccaaca gtgtaaatgc atagcagtgt ttatctgcat gagaactatg cactaatcta     7140

tctgaagaaa aaaactatat caactttggt atctactttc cgtttacttc aatccttgcc     7200

tttttggtca ttgttataat gccagcttta ggacagaaag aattataaga aaaccagcat     7260

aatacctgat atattaaaat gtagtgcctg tgaaatctgt attatattgc tcttctgaag     7320

taagattttt ctacaccggt agccttcgct gtctgtcagt caggaccttc tggtataggt     7380

gatgtaaaat aaccgtacaa tattaatgca tgcgattcca taatgcttag tgaactgtat     7440

gaatattact caaagttatg ttagtctttt tttccgactt ggttcttgtc agctaggttt     7500

aaaggtattt cactgagaac gcaaattctg tcttttcttg atttcggctg ttttcagtat     7560

tttggaggta tacatttact taaattcagt attactcgtg ttttgttttt gtttttgttt     7620

tttgttttct ttttcctagg ggacaagcat gggtgtttga tttcagaaat cagtacctgg     7680

cgagattttt gtctcaaaac gactatttga atttcaagaa ctgtgctgcg aagacactct     7740

gagaacattt gcaagtcagg ggcattttcc ttgacccttg actgatgcta tgcggagact     7800

gatacatttt cttaatggac aatgttcaag ccaggtaccc atgcttgatc tgtcttcaca     7860

ccagacctcc tcatattaaa aggaaaaata agaaaaaaaa tgtaagaaat cacatggcta     7920

tttagtttca tgcacagttg caatattttc ttcaaaaata aaactctgta caaactttgg     7980

gcccgattca taagaaaaag aagtttgcta ttaacacggg atttttttaa tatacttttt     8040

ttggtctaaa tttgaaatta cttgcttccc aaattaaata aatttcatct catttttttc     8100

cctaaaccag cacccatctg ccttttattc cccaaagagt tacctttccc agattagggg     8160

gatggtatgt ggggagcaga tagcggaaat gcttagaaag ataaggggga ccacccacag     8220

ctggtcgtga gaacagggag acagtgtgtg ggggtgggac ctcatctgtg tgcctggtat     8280

cctgagtttt acatgtagat gcattcgcct atttgattca gaaaaataaa ctttcccaaa     8340

atgtgtctga accacaagag catacagtgg aagtgctacc tctaatctaa ccagagcacc     8400

ttcatggtgg aagacaccca ccaggtcata caatgtgaac ttttgtatct ctgcagtggt     8460

ttcaaggaca aatagtgtcc aatgtattgg gccatttttc ctgctgtttt tatactcaac     8520

ttctcaaaat gaaaaaagct tttatttttc ctttgactta tttgtgttgt tcttattttt     8580

taaattttta ttttttgata atagtctgta agttagcctt tttgggtttt tttttttttt     8640

ttttggcttt tttttttgtt tgtttttttt tcttttgaca ttgcaaccga aggtcataag     8700

gccgctagct ccgctgggac agaggcttga gagaactaac ggctcggtgc cttctccctg     8760

gtctcagacc atcgtctctg cactgcgaag gcatttggta gcctcgccac tgagatacta     8820

actagaccta gactaggagc tttatcaggt tctaggaggt cctttaggaa gactctcaaa     8880

ggcaaatccc tgatcccccg ccccaccctt agccctgccc tctcaccaga gcaaaattca     8940

ctggggactt ttcccaccac acatggaaat ctgtccactc ggaatacctc tgttttccat     9000

ttcaaattgt agggggaggg gatggaacac ttccagtgat ggtaagagat ctgttatgaa     9060

acgaaacacc ccccgtgtta ataacttggt ctgaaatctg tttttatgag ccgggccccc     9120

tgtgcctcta gtatacttgt attgactctc atagttaccc ttttagtttt actgtgttct     9180

gtgaaaattt gtaattggtt gagaatcact gtgggcgtcc attcttattc aactaaatct     9240

ccacaggttt tttgagctgg tgtggattag tttaactctt gtattcaacc attagtgcta     9300

ccaccttctc acattacaat acaattactg gaagcaagta ctgcatttcc tatgcaacaa     9360

aaaaggaaaa ataaaaaatt gctaatgcta aaaaaaaaaa aaa                       9403


<210>  2349
<211>  4093
<212>  DNA
<213>  homo sapiens

<400>  2349
gtgagagagt gagcgagaca gaaagagaga gaagtgcacc agcgagccgg ggcaggaaga       60

ggaggtttcg ccaccggagc ggcccggcga cgcgctgaca gcttcccctg cccttcccgt      120

cggtcgggcc gccagccgcc gcagccctcg gcctgcacgc agccaccggc cccgctcccg      180

gagcccagcg ccgccgaggc cgcagccgcc cggccagtaa ggcggcgccg ccgcccggcc      240

accgcgcgcc ctgcgcttcc ctccgcccgc gctgcggcca tggcgcggcg ctgactggcc      300

tggcccggcc ccgccgcgct cccgctcgcc ccgacccgca ctcgggcccg cccgggctcc      360

ggcctgccgc cgcctcttcc ttctccagcc ggcaggcccg cgccgcttag gagggagagc      420

ccacccgcgc caggaggccg aacgcggact cgccacccgg cttcagaatg gcagaagatg      480

atccatattt gggaaggcct gaacaaatgt ttcatttgga tccttctttg actcatacaa      540

tatttaatcc agaagtattt caaccacaga tggcactgcc aacagcagat ggcccatacc      600

ttcaaatatt agagcaacct aaacagagag gatttcgttt ccgttatgta tgtgaaggcc      660

catcccatgg tggactacct ggtgcctcta gtgaaaagaa caagaagtct taccctcagg      720

tcaaaatctg caactatgtg ggaccagcaa aggttattgt tcagttggtc acaaatggaa      780

aaaatatcca cctgcatgcc cacagcctgg tgggaaaaca ctgtgaggat gggatctgca      840

ctgtaactgc tggacccaag gacatggtgg tcggcttcgc aaacctgggt atacttcatg      900

tgacaaagaa aaaagtattt gaaacactgg aagcacgaat gacagaggcg tgtataaggg      960

gctataatcc tggactcttg gtgcaccctg accttgccta tttgcaagca gaaggtggag     1020

gggaccggca gctgggagat cgggaaaaag agctaatccg ccaagcagct ctgcagcaga     1080

ccaaggagat ggacctcagc gtggtgcggc tcatgtttac agcttttctt ccggatagca     1140

ctggcagctt cacaaggcgc ctggaacccg tggtatcaga cgccatctat gacagtaaag     1200

cccccaatgc atccaacttg aaaattgtaa gaatggacag gacagctgga tgtgtgactg     1260

gaggggagga aatttatctt ctttgtgaca aagttcagaa agatgacatc cagattcgat     1320

tttatgaaga ggaagaaaat ggtggagtct gggaaggatt tggagatttt tcccccacag     1380

atgttcatag acaatttgcc attgtcttca aaactccaaa gtataaagat attaatatta     1440

caaaaccagc ctctgtgttt gtccagcttc ggaggaaatc tgacttggaa actagtgaac     1500

caaaaccttt cctctactat cctgaaatca aagataaaga agaagtgcag aggaaacgtc     1560

agaagctcat gcccaatttt tcggatagtt tcggcggtgg tagtggtgct ggagctggag     1620

gcggaggcat gtttggtagt ggcggtggag gagggggcac tggaagtaca ggtccagggt     1680

atagcttccc acactatgga tttcctactt atggtgggat tactttccat cctggaacta     1740

ctaaatctaa tgctgggatg aagcatggaa ccatggacac tgaatctaaa aaggaccctg     1800

aaggttgtga caaaagtgat gacaaaaaca ctgtaaacct ctttgggaaa gttattgaaa     1860

ccacagagca agatcaggag cccagcgagg ccaccgttgg gaatggtgag gtcactctaa     1920

cgtatgcaac aggaacaaaa gaagagagtg ctggagttca ggataacctc tttctagaga     1980

aggctatgca gcttgcaaag aggcatgcca atgccctttt cgactacgcg gtgacaggag     2040

acgtgaagat gctgctggcc gtccagcgcc atctcactgc tgtgcaggat gagaatgggg     2100

acagtgtctt acacttagca atcatccacc ttcattctca acttgtgagg gatctactag     2160

aagtcacatc tggtttgatt tctgatgaca ttatcaacat gagaaatgat ctgtaccaga     2220

cgcccttgca cttggcagtg atcactaagc aggaagatgt ggtggaggat ttgctgaggg     2280

ctggggccga cctgagcctt ctggaccgct tgggtaactc tgttttgcac ctagctgcca     2340

aagaaggaca tgataaagtt ctcagtatct tactcaagca caaaaaggca gcactacttc     2400

ttgaccaccc caacggggac ggtctgaatg ccattcatct agccatgatg agcaatagcc     2460

tgccatgttt gctgctgctg gtggccgctg gggctgacgt caatgctcag gagcagaagt     2520

ccgggcgcac agcactgcac ctggctgtgg agcacgacaa catctcattg gcaggctgcc     2580

tgctcctgga gggtgatgcc catgtggaca gtactaccta cgatggaacc acacccctgc     2640

atatagcagc tgggagaggg tccaccaggc tggcagctct tctcaaagca gcaggagcag     2700

atcccctggt ggagaacttt gagcctctct atgacctgga tgactcttgg gaaaatgcag     2760

gagaggatga aggagttgtg cctggaacca cgcctctaga tatggccacc agctggcagg     2820

tatttgacat attaaatggg aaaccatatg agccagagtt tacatctgat gatttactag     2880

cacaaggaga catgaaacag ctggctgaag atgtgaagct gcagctgtat aagttactag     2940

aaattcctga tccagacaaa aactgggcta ctctggcgca gaaattaggt ctggggatac     3000

ttaataatgc cttccggctg agtcctgctc cttccaaaac acttatggac aactatgagg     3060

tctctggggg tacagtcaga gagctggtgg aggccctgag acaaatgggc tacaccgaag     3120

caattgaagt gatccaggca gcctccagcc cagtgaagac cacctctcag gcccactcgc     3180

tgcctctctc gcctgcctcc acaaggcagc aaatagacga gctccgagac agtgacagtg     3240

tctgcgacag cggcgtggag acatccttcc gcaaactcag ctttaccgag tctctgacca     3300

gtggtgcctc actgctaact ctcaacaaaa tgccccatga ttatgggcag gaaggacctc     3360

tagaaggcaa aatttagcct gctgacaatt tcccacaccg tgtaaaccaa agccctaaaa     3420

ttccactgcg ttgtccacaa gacagaagct gaagtgcatc caaaggtgct cagagagccg     3480

gcccgcctga atcattctcg atttaactcg agaccttttc aacttggctt cctttcttgg     3540

ttcataaatg aattttagtt tggttcactt acagatagta tctagcaatc acaacactgg     3600

ctgagcggat gcatctgggg atgaggttgc ttactaagct ttgccagctg ctgctggatc     3660

acagctgctt tctgttgtca ttgctgttgt ccctctgcta cgttcctatt gtcattaaag     3720

gtatcacggt cgccacctgg cattccttct gaccacagca tcattttgca ttcaaattaa     3780

gggttaagaa aagagatatt ttaaaatgag agtcacttga tgtgccattt taaaaaaaaa     3840

ggcatattgc tttttctaat gtggttattt ctctgatttg caaaaaaaaa aaaaaaaaaa     3900

atacttgtca atatttaaac atggttacaa tcattgctga aaatggtatt ttcccccttt     3960

tctgcatttt gctattgtaa atatgttttt tagatcaaat actttaaagg aaaaaatgtt     4020

ggatttataa atgctatttt ttattttact tttataataa aaggaaaagc aaattgatga     4080

cctcaaaaaa aaa                                                        4093


<210>  2350
<211>  4090
<212>  DNA
<213>  homo sapiens

<400>  2350
gtgagagagt gagcgagaca gaaagagaga gaagtgcacc agcgagccgg ggcaggaaga       60

ggaggtttcg ccaccggagc ggcccggcga cgcgctgaca gcttcccctg cccttcccgt      120

cggtcgggcc gccagccgcc gcagccctcg gcctgcacgc agccaccggc cccgctcccg      180

gagcccagcg ccgccgaggc cgcagccgcc cggccagtaa ggcggcgccg ccgcccggcc      240

accgcgcgcc ctgcgcttcc ctccgcccgc gctgcggcca tggcgcggcg ctgactggcc      300

tggcccggcc ccgccgcgct cccgctcgcc ccgacccgca ctcgggcccg cccgggctcc      360

ggcctgccgc cgcctcttcc ttctccagcc ggcaggcccg cgccgcttag gagggagagc      420

ccacccgcgc caggaggccg aacgcggact cgccacccgg cttcagaatg gcagaagatg      480

atccatattt gggaaggcct gaacaaatgt ttcatttgga tccttctttg actcatacaa      540

tatttaatcc agaagtattt caaccacaga tggcactgcc aacagatggc ccataccttc      600

aaatattaga gcaacctaaa cagagaggat ttcgtttccg ttatgtatgt gaaggcccat      660

cccatggtgg actacctggt gcctctagtg aaaagaacaa gaagtcttac cctcaggtca      720

aaatctgcaa ctatgtggga ccagcaaagg ttattgttca gttggtcaca aatggaaaaa      780

atatccacct gcatgcccac agcctggtgg gaaaacactg tgaggatggg atctgcactg      840

taactgctgg acccaaggac atggtggtcg gcttcgcaaa cctgggtata cttcatgtga      900

caaagaaaaa agtatttgaa acactggaag cacgaatgac agaggcgtgt ataaggggct      960

ataatcctgg actcttggtg caccctgacc ttgcctattt gcaagcagaa ggtggagggg     1020

accggcagct gggagatcgg gaaaaagagc taatccgcca agcagctctg cagcagacca     1080

aggagatgga cctcagcgtg gtgcggctca tgtttacagc ttttcttccg gatagcactg     1140

gcagcttcac aaggcgcctg gaacccgtgg tatcagacgc catctatgac agtaaagccc     1200

ccaatgcatc caacttgaaa attgtaagaa tggacaggac agctggatgt gtgactggag     1260

gggaggaaat ttatcttctt tgtgacaaag ttcagaaaga tgacatccag attcgatttt     1320

atgaagagga agaaaatggt ggagtctggg aaggatttgg agatttttcc cccacagatg     1380

ttcatagaca atttgccatt gtcttcaaaa ctccaaagta taaagatatt aatattacaa     1440

aaccagcctc tgtgtttgtc cagcttcgga ggaaatctga cttggaaact agtgaaccaa     1500

aacctttcct ctactatcct gaaatcaaag ataaagaaga agtgcagagg aaacgtcaga     1560

agctcatgcc caatttttcg gatagtttcg gcggtggtag tggtgctgga gctggaggcg     1620

gaggcatgtt tggtagtggc ggtggaggag ggggcactgg aagtacaggt ccagggtata     1680

gcttcccaca ctatggattt cctacttatg gtgggattac tttccatcct ggaactacta     1740

aatctaatgc tgggatgaag catggaacca tggacactga atctaaaaag gaccctgaag     1800

gttgtgacaa aagtgatgac aaaaacactg taaacctctt tgggaaagtt attgaaacca     1860

cagagcaaga tcaggagccc agcgaggcca ccgttgggaa tggtgaggtc actctaacgt     1920

atgcaacagg aacaaaagaa gagagtgctg gagttcagga taacctcttt ctagagaagg     1980

ctatgcagct tgcaaagagg catgccaatg cccttttcga ctacgcggtg acaggagacg     2040

tgaagatgct gctggccgtc cagcgccatc tcactgctgt gcaggatgag aatggggaca     2100

gtgtcttaca cttagcaatc atccaccttc attctcaact tgtgagggat ctactagaag     2160

tcacatctgg tttgatttct gatgacatta tcaacatgag aaatgatctg taccagacgc     2220

ccttgcactt ggcagtgatc actaagcagg aagatgtggt ggaggatttg ctgagggctg     2280

gggccgacct gagccttctg gaccgcttgg gtaactctgt tttgcaccta gctgccaaag     2340

aaggacatga taaagttctc agtatcttac tcaagcacaa aaaggcagca ctacttcttg     2400

accaccccaa cggggacggt ctgaatgcca ttcatctagc catgatgagc aatagcctgc     2460

catgtttgct gctgctggtg gccgctgggg ctgacgtcaa tgctcaggag cagaagtccg     2520

ggcgcacagc actgcacctg gctgtggagc acgacaacat ctcattggca ggctgcctgc     2580

tcctggaggg tgatgcccat gtggacagta ctacctacga tggaaccaca cccctgcata     2640

tagcagctgg gagagggtcc accaggctgg cagctcttct caaagcagca ggagcagatc     2700

ccctggtgga gaactttgag cctctctatg acctggatga ctcttgggaa aatgcaggag     2760

aggatgaagg agttgtgcct ggaaccacgc ctctagatat ggccaccagc tggcaggtat     2820

ttgacatatt aaatgggaaa ccatatgagc cagagtttac atctgatgat ttactagcac     2880

aaggagacat gaaacagctg gctgaagatg tgaagctgca gctgtataag ttactagaaa     2940

ttcctgatcc agacaaaaac tgggctactc tggcgcagaa attaggtctg gggatactta     3000

ataatgcctt ccggctgagt cctgctcctt ccaaaacact tatggacaac tatgaggtct     3060

ctgggggtac agtcagagag ctggtggagg ccctgagaca aatgggctac accgaagcaa     3120

ttgaagtgat ccaggcagcc tccagcccag tgaagaccac ctctcaggcc cactcgctgc     3180

ctctctcgcc tgcctccaca aggcagcaaa tagacgagct ccgagacagt gacagtgtct     3240

gcgacagcgg cgtggagaca tccttccgca aactcagctt taccgagtct ctgaccagtg     3300

gtgcctcact gctaactctc aacaaaatgc cccatgatta tgggcaggaa ggacctctag     3360

aaggcaaaat ttagcctgct gacaatttcc cacaccgtgt aaaccaaagc cctaaaattc     3420

cactgcgttg tccacaagac agaagctgaa gtgcatccaa aggtgctcag agagccggcc     3480

cgcctgaatc attctcgatt taactcgaga ccttttcaac ttggcttcct ttcttggttc     3540

ataaatgaat tttagtttgg ttcacttaca gatagtatct agcaatcaca acactggctg     3600

agcggatgca tctggggatg aggttgctta ctaagctttg ccagctgctg ctggatcaca     3660

gctgctttct gttgtcattg ctgttgtccc tctgctacgt tcctattgtc attaaaggta     3720

tcacggtcgc cacctggcat tccttctgac cacagcatca ttttgcattc aaattaaggg     3780

ttaagaaaag agatatttta aaatgagagt cacttgatgt gccattttaa aaaaaaaggc     3840

atattgcttt ttctaatgtg gttatttctc tgatttgcaa aaaaaaaaaa aaaaaaaata     3900

cttgtcaata tttaaacatg gttacaatca ttgctgaaaa tggtattttc ccccttttct     3960

gcattttgct attgtaaata tgttttttag atcaaatact ttaaaggaaa aaatgttgga     4020

tttataaatg ctatttttta ttttactttt ataataaaag gaaaagcaaa ttgatgacct     4080

caaaaaaaaa                                                            4090


<210>  2351
<211>  3125
<212>  DNA
<213>  homo sapiens

<400>  2351
ccgcaaccag agccgccgcc acggtgagtg gctggattca gacccctggg tggccgggac       60

aagagaaaag agggaggagg gcctttagcg gacagcgcct ggggctggag agcagcagct      120

gcacacagcc ggaaagggcg cgcaggcgac gacactcgga tccacgtcga caccgttgta      180

caaagatacg cggacccgcg ggcgtctaaa attctgggaa gcagaacctg gccggagcca      240

ctagacagag ccgggcctag cccagagaca tggagagttg ctacaaccca ggtctggatg      300

gtattattga atatgatgat ttcaaattga actcctccat tgtggaaccc aaggagccag      360

ccccagaaac agctgatggc ccctacctgg tgatcgtgga acagcctaag cagagaggct      420

tccgatttcg atatggctgt gaaggcccct cccatggagg actgcccggt gcctccagtg      480

agaagggccg aaagacctat cccactgtca agatctgtaa ctacgaggga ccagccaaga      540

tcgaggtgga cctggtaaca cacagtgacc cacctcgtgc tcatgcccac agtctggtgg      600

gcaagcaatg ctcggagctg gggatctgcg ccgtttctgt ggggcccaag gacatgactg      660

cccaatttaa caacctgggt gtcctgcatg tgactaagaa gaacatgatg gggactatga      720

tacaaaaact tcagaggcag cggctccgct ctaggcccca gggccttacg gaggccgagc      780

agcgggagct ggagcaagag gccaaagaac tgaagaaggt gatggatctg agtatagtgc      840

ggctgcgctt ctctgccttc cttagagcca gtgatggctc cttctccctg cccctgaagc      900

cagtcatctc ccagcccatc catgacagca aatctccggg ggcatcaaac ctgaagattt      960

ctcgaatgga caagacagca ggctctgtgc ggggtggaga tgaagtttat ctgctttgtg     1020

acaaggtgca gaaagatgac attgaggttc ggttctatga ggatgatgag aatggatggc     1080

aggcctttgg ggacttctct cccacagatg tgcataaaca gtatgccatt gtgttccgga     1140

caccccccta tcacaagatg aagattgagc ggcctgtaac agtgtttctg caactgaaac     1200

gcaagcgagg aggggacgtg tctgattcca aacagttcac ctattaccct ctggtggaag     1260

acaaggaaga ggtgcagcgg aagcggagga aggccttgcc caccttctcc cagcccttcg     1320

ggggtggctc ccacatgggt ggaggctctg ggggtgcagc cgggggctac ggaggagctg     1380

gaggaggtgg cagcctcggt ttcttcccct cctccctggc ctacagcccc taccagtccg     1440

gcgcgggccc catgggctgc tacccgggag gcgggggcgg ggcgcagatg gccgccacgg     1500

tgcccagcag ggactccggg gaggaagccg cggagccgag cgccccctcc aggacccccc     1560

agtgcgagcc gcaggccccg gagatgctgc agcgagctcg agagtacaac gcgcgcctgt     1620

tcggcctggc gcagcgcagc gcccgagccc tactcgacta cggcgtcacc gcggacgcgc     1680

gcgcgctgct ggcgggacag cgccacctgc tgacggcgca ggacgagaac ggagacacac     1740

cactgcacct agccatcatc cacgggcaga ccagtgtcat tgagcagata gtctatgtca     1800

tccaccacgc ccaggacctc ggcgttgtca acctcaccaa ccacctgcac cagacgcccc     1860

tgcacctggc ggtgatcacg gggcagacga gtgtggtgag ctttctgctg cgggtaggtg     1920

cagacccagc tctgctggat cggcatggag actcagccat gcatctggcg ctgcgggcag     1980

gcgctggtgc tcctgagctg ctgcgtgcac tgcttcagag tggagctcct gctgtgcccc     2040

agctgttgca tatgcctgac tttgagggac tgtatccagt acacctggcg gtccgagccc     2100

gaagccctga gtgcctggat ctgctggtgg acagtggggc tgaagtggag gccacagagc     2160

ggcagggggg acgaacagcc ttgcatctag ccacagagat ggaggagctg gggttggtca     2220

cccatctggt caccaagctc cgggccaacg tgaacgctcg cacctttgcg ggaaacacac     2280

ccctgcacct ggcagctgga ctggggtacc cgaccctcac ccgcctcctt ctgaaggctg     2340

gtgctgacat ccatgctgaa aacgaggagc ccctgtgccc actgccttca ccccctacct     2400

ctgatagcga ctcggactct gaagggcctg agaaggacac ccgaagcagc ttccggggcc     2460

acacgcctct tgacctcact tgcagcacca aggtgaagac cttgctgcta aatgctgctc     2520

agaacaccat ggagccaccc ctgaccccgc ccagcccagc agggccggga ctgtcacttg     2580

gtgatacagc tctgcagaac ctggagcagc tgctagacgg gccagaagcc cagggcagct     2640

gggcagagct ggcagagcgt ctggggctgc gcagcctggt agacacgtac cgacagacaa     2700

cctcacccag tggcagcctc ctgcgcagct acgagctggc tggcggggac ctggcaggtc     2760

tactggaggc cctgtctgac atgggcctag aggagggagt gaggctgctg aggggtccag     2820

aaacccgaga caagctgccc agcacagcag aggtgaagga agacagtgcg tacgggagcc     2880

agtcagtgga gcaggaggca gagaagctgg gcccaccccc tgagccacca ggagggctct     2940

gccacgggca cccccagcct caggtgcact gacctgctgc ctgcccccag cccccttccc     3000

ggaccccctg tacagcgtcc ccacctattt caaatcttat ttaacacccc acacccaccc     3060

ctcagttggg acaaataaag gattctcatg ggaaggggag gacccctcct tcccaactta     3120

tggca                                                                 3125


<210>  2352
<211>  3126
<212>  DNA
<213>  homo sapiens

<400>  2352
gcctcccgcc cctcccgtcg cgagggcggg gccagtggcg tcatttccag gcccgccccc       60

tccggccccg cctccccttg gtattttcgg gactttccta agctgctcta actttcctgc      120

cccttccccg gccaagccca actccggatc tcgctctcca ccggatctca cccgccacac      180

ccggacaggc ggctggagga ggcgggcgtc taaaattctg ggaagcagaa cctggccgga      240

gccactagac agagccgggc ctagcccaga gacatggaga gttgctacaa cccaggtctg      300

gatggtatta ttgaatatga tgatttcaaa ttgaactcct ccattgtgga acccaaggag      360

ccagccccag aaacagctga tggcccctac ctggtgatcg tggaacagcc taagcagaga      420

ggcttccgat ttcgatatgg ctgtgaaggc ccctcccatg gaggactgcc cggtgcctcc      480

agtgagaagg gccgaaagac ctatcccact gtcaagatct gtaactacga gggaccagcc      540

aagatcgagg tggacctggt aacacacagt gacccacctc gtgctcatgc ccacagtctg      600

gtgggcaagc aatgctcgga gctggggatc tgcgccgttt ctgtggggcc caaggacatg      660

actgcccaat ttaacaacct gggtgtcctg catgtgacta agaagaacat gatggggact      720

atgatacaaa aacttcagag gcagcggctc cgctctaggc cccagggcct tacggaggcc      780

gagcagcggg agctggagca agaggccaaa gaactgaaga aggtgatgga tctgagtata      840

gtgcggctgc gcttctctgc cttccttaga gccagtgatg gctccttctc cctgcccctg      900

aagccagtca tctcccagcc catccatgac agcaaatctc cgggggcatc aaacctgaag      960

atttctcgaa tggacaagac agcaggctct gtgcggggtg gagatgaagt ttatctgctt     1020

tgtgacaagg tgcagaaaga tgacattgag gttcggttct atgaggatga tgagaatgga     1080

tggcaggcct ttggggactt ctctcccaca gatgtgcata aacagtatgc cattgtgttc     1140

cggacacccc cctatcacaa gatgaagatt gagcggcctg taacagtgtt tctgcaactg     1200

aaacgcaagc gaggagggga cgtgtctgat tccaaacagt tcacctatta ccctctggtg     1260

gaagacaagg aagaggtgca gcggaagcgg aggaaggcct tgcccacctt ctcccagccc     1320

ttcgggggtg gctcccacat gggtggaggc tctgggggtg cagccggggg ctacggagga     1380

gctggaggag gtggcagcct cggtttcttc ccctcctccc tggcctacag cccctaccag     1440

tccggcgcgg gccccatggg ctgctacccg ggaggcgggg gcggggcgca gatggccgcc     1500

acggtgccca gcagggactc cggggaggaa gccgcggagc cgagcgcccc ctccaggacc     1560

ccccagtgcg agccgcaggc cccggagatg ctgcagcgag ctcgagagta caacgcgcgc     1620

ctgttcggcc tggcgcagcg cagcgcccga gccctactcg actacggcgt caccgcggac     1680

gcgcgcgcgc tgctggcggg acagcgccac ctgctgacgg cgcaggacga gaacggagac     1740

acaccactgc acctagccat catccacggg cagaccagtg tcattgagca gatagtctat     1800

gtcatccacc acgcccagga cctcggcgtt gtcaacctca ccaaccacct gcaccagacg     1860

cccctgcacc tggcggtgat cacggggcag acgagtgtgg tgagctttct gctgcgggta     1920

ggtgcagacc cagctctgct ggatcggcat ggagactcag ccatgcatct ggcgctgcgg     1980

gcaggcgctg gtgctcctga gctgctgcgt gcactgcttc agagtggagc tcctgctgtg     2040

ccccagctgt tgcatatgcc tgactttgag ggactgtatc cagtacacct ggcggtccga     2100

gcccgaagcc ctgagtgcct ggatctgctg gtggacagtg gggctgaagt ggaggccaca     2160

gagcggcagg ggggacgaac agccttgcat ctagccacag agatggagga gctggggttg     2220

gtcacccatc tggtcaccaa gctccgggcc aacgtgaacg ctcgcacctt tgcgggaaac     2280

acacccctgc acctggcagc tggactgggg tacccgaccc tcacccgcct ccttctgaag     2340

gctggtgctg acatccatgc tgaaaacgag gagcccctgt gcccactgcc ttcaccccct     2400

acctctgata gcgactcgga ctctgaaggg cctgagaagg acacccgaag cagcttccgg     2460

ggccacacgc ctcttgacct cacttgcagc accaaggtga agaccttgct gctaaatgct     2520

gctcagaaca ccatggagcc acccctgacc ccgcccagcc cagcagggcc gggactgtca     2580

cttggtgata cagctctgca gaacctggag cagctgctag acgggccaga agcccagggc     2640

agctgggcag agctggcaga gcgtctgggg ctgcgcagcc tggtagacac gtaccgacag     2700

acaacctcac ccagtggcag cctcctgcgc agctacgagc tggctggcgg ggacctggca     2760

ggtctactgg aggccctgtc tgacatgggc ctagaggagg gagtgaggct gctgaggggt     2820

ccagaaaccc gagacaagct gcccagcaca gaggtgaagg aagacagtgc gtacgggagc     2880

cagtcagtgg agcaggaggc agagaagctg ggcccacccc ctgagccacc aggagggctc     2940

tgccacgggc acccccagcc tcaggtgcac tgacctgctg cctgccccca gcccccttcc     3000

cggaccccct gtacagcgtc cccacctatt tcaaatctta tttaacaccc cacacccacc     3060

cctcagttgg gacaaataaa ggattctcat gggaagggga ggacccctcc ttcccaactt     3120

atggca                                                                3126


<210>  2353
<211>  6236
<212>  DNA
<213>  homo sapiens

<400>  2353
cattttgcta ggcagcggca gtggcggcgg cagcggcggc tggagcctct gattgggttt       60

cggagtccgg tactggagcc aatcagcgcg ggcagcgaac cgggggagcg aggcacggag      120

tgtacctcac agccttctag gatctccaga gtggacagga atctcacttg gagggaccat      180

ggagcagtat acagcaaaca gcaatagttc gacagagcag attgttgtcc aggcaggaca      240

gattcagcag cagcagcagg gtggtgtcac tgctgtgcag ttgcagactg aggcccaggt      300

ggcatccgcc tcaggccagc aagtccagac cctccaggta gtccaagggc agccattaat      360

ggtgcaggtc agtggaggcc agctaatcac atcaactggc caacccatca tggtccaggc      420

tgtccctggt ggacaaggtc aaaccatcat gcaagtacct gtttctggaa cacagggttt      480

gcagcaaata cagttggtcc cacctggaca gatccagatc cagggtggac aggctgtgca      540

ggtgcagggc cagcagggcc agacccagca gatcatcatc cagcagcccc agacggctgt      600

cactgctggc cagactcaga cacagcagca gattgctgtc cagggacagc aagtggcaca      660

gactgctgaa gggcagacca tcgtctatca accagttaat gcagatggca ccattctcca      720

gcaagttaca gtccctgttt caggcatgat cactatccca gcagccagtt tggcaggagc      780

acagattgtt caaacaggag ccaataccaa cacaaccagc agtgggcaag ggactgtcac      840

tgtgacacta ccagtggcag gcaatgtggt caattcagga gggatggtca tgatggttcc      900

tggggctggc tctgtgcctg ctatccaaag aatccctcta cctggagcag agatgcttga      960

agaagagcct ctctacgtga atgccaaaca ataccaccgt attcttaaga ggaggcaagc     1020

ccgagctaaa ctagaggcag aagggaaaat tccaaaggag agaaggaaat acctgcatga     1080

gtctcggcac cgtcatgcca tggcacggaa gcgtggtgaa ggtggacgat ttttctctcc     1140

aaaggaaaag gatagtcccc atatgcagga tccaaaccaa gccgatgaag aagcaatgac     1200

acagatcatc cgagtgtcct aaccccacgc catgtgatgg agctgatcaa ggtcatgttt     1260

ctcactgttc caggaaattg atcaactctt ccaatgggac attgatgatc acattctgcc     1320

ctttactaca ggacagaaac cacttagttt ttaataagtg gctcagtatt acaattgcag     1380

cgatgcctgg caaattgaag ttgcaagcct ttgtcttact ctttcagtca ggacctattt     1440

cagactgttg atgacattga catttcatgg attcggatga tgcaaggaga cacatgccac     1500

cccagcagta cacaaagcac ttaccttgac tggtgaagtc agccagccat ctcagcaggg     1560

aagaacaacc ttctcaacca aaactgcaat caggaaagca gcagcccact ccttcccatg     1620

gaatctagac agcatttatc cctctggtgg gggaatctca cactgactaa ctgaatggac     1680

gctttgtatt cagagatggc ttccaggcaa ggaagttcta tcttgtgata cggaaacaat     1740

aaattcctga gatacattct tccaatctgt ggtaataata agaattcctc tctgcccaga     1800

tggtaggttg atatttctgg actctagcca agaaaaagct aattctgggg atagaatgat     1860

aaaagactca agcactaaaa atatacattg ccgaatctct ttttctagct ttgaaaagtt     1920

gtggcctgct tgtccctctg ttgactggtc atctggacca tcgtacttgc tgtggctact     1980

tctaagacaa tgtagagggt tattaaacct tgaaactgcc tttcctaagt agagaacaag     2040

actattcaac aacttctttg ctgaagcact gaggagattt gtaatactcc taaaggaagg     2100

gccaaactag agattttcaa tcatagactt tgtgacagca tttggggaac taaaagattc     2160

atgtgtttca gcctagtggg agagagtggg ggagaggaag agagagagag agcatgtata     2220

cccgtatgtt atcatagagc acgattctcc agtggatgga tacctggaat ggatcattaa     2280

gatgaagaga gtaattcaca tttactctag aacctttaac aagcactgaa aggaagaagc     2340

ctgagatttg atccttgaca atttctggaa agcactggtc agtcacactg tcctggacag     2400

agtccaagtt acccactaaa gcttgaggtg gatgttggct tcactcctgc agcacaatgc     2460

tggccctaga aagcgagcat tttcattctt cccatggcag ctgattcttt ggtgccagtt     2520

ttcatgtttt ctccataggc cttgtgcaga aaggttttct cattgcatcc atactgtgag     2580

aataaactgc agactgaaag aaacatgcct gcagggtcag gaactgggcc actgttccca     2640

gaacgggttg tgcctcagaa atctatttct cttttagatg ttgaaccctg agagaactaa     2700

gatgatattt cagaagagtt ggctgccttc tctggaaaca aggaaaaccc aataattccg     2760

aggaacattg ggggttaaat accaagaata aaaattggtt cttctttgac ttcagcttaa     2820

ctgtattaag acagaaatta agccctctaa aaacaccaca aagagagatg attgtaatga     2880

tagaaataga ggtacagagc tatgcaaagg aaacaggaag tgaaatattc ctagtcccag     2940

ggatctggta atcgctcctg gcttccagat gtcaaaggac tgatcctttg gtaagctcac     3000

tagaaacttc tagctctaca agagtttggg atattaatgt tattcagtaa gtcccaagtt     3060

tttcagagaa tagattacta acaatgagga atttatattc cttggttaat ttaggagtct     3120

aagatgcaga gttcagaaag aaattactca gacctaactt tgagtgctta agctgccaac     3180

agttagaaga tgctatttat ttgtgtctgt aagtttgtac atagtaatgc cagccttgtt     3240

gctgaatttt ttatttgggg ggagatgact ttgaattttg tttgaaatgc ttcagttgtc     3300

attttgtcat tgcatttcaa atagctcatg acccttttct tgtggtcact ttggcacacc     3360

atagtagccc acaaagtggg ggcagggtat tgacatttgg attttttctt tgatactagt     3420

tcttttattc atttttattt gtgactgtag tgataacttt acagatggag aaagagtgaa     3480

tggatgaatg aataattggt ttaatgccta gttatgcaac ttgagtgctt tttttttttt     3540

ttgcaggata attttaagtg tatatatttt aactgcactg gtacattgaa catgtcagtg     3600

tcgatgccac tggaccaaca gagcattttg tggctatagg gtgcctgata ataatgtctt     3660

gatttttctt tgggattcaa ctatatcgaa ggtttttccc ccagcagtat gggggcgtac     3720

aggtgatcga tcattaatgt cattgcaatt gttatttttt aaaataaatt tataaaaata     3780

accgaaaagt aatgtgactt ttgaggaatc tgcaactcct gggttctagt ttgtgtttcc     3840

agtgttgaaa ttttgatctc ccccgacaag acttgtctgc atggacggtg tctctgtaaa     3900

cagtatcaaa cttgtaatgt ctgagcctct tagctttatc tccccttaat ttcttccctt     3960

ttggcccttc caccctgttg aggagatttt ttctgtcacc tgcaggctga tcatacattt     4020

gatgctacta ctgaaagtgt ttatcaaaat gtgatgaagt aattccatga ggaaaattag     4080

ccgttatcac aaaaacagcc ttaagtattg tagaatttca ggtagtgaag atgtactatt     4140

tacgttttgt tagattttgt tttggcagaa gaccaaaaca aaagtacttt tctgattgtt     4200

aaaaatccac agcatgctca ccttgttact gttttacctt acggtcgctg ggaatctaag     4260

caacaaagac tagaagcctc cgatatgcca ttatcaacac acaagagaca aacagcccga     4320

ggaagcactc aatgatgaga gcagtagacc tgccctggca gatgagagag gagaaactct     4380

ccacaatgaa ggaaaagcac tgacagtatt tgatagcttt agtcaaactg tgcttgagtt     4440

tggcttagat ttatgccagt ggaacctgtc cttaccaaat tcagagatga cccaagattc     4500

tactctgtgg tatgagggaa agacctctcg atatttatct cacaccaacg gctttatcgt     4560

aggagcgtct tcgcctcccc cgtttccagt agaaaagaca gctttgctcc tttgaaagcg     4620

cagaccgccg cacctccagc cccttctccc cggggaagta ggccccgcta agaatgtggg     4680

aaggtggtgg ggcggcgact gaagtcgctt ccgattggcg ttgtcccaag gaagcctgcg     4740

cggattgatc ggcggcaggc ctccaataga gcctgctagg cggattggct gctacgcggc     4800

tgggccctgt ttccggtacc taggcgggca gccatggtga ccggcgagcg gcatgcgacg     4860

ccgcctctgt ggcctgtgga ggcccgcttg gcggcgctgc ttcccgacct actggtcttt     4920

cggaagcctc ggggatggga acccgagctc gccacggccc agggcgtcct cctaggcgtc     4980

catgtgacgg gtgagggcga cggccggcac ttgcacttaa gtctcctggc ctgcgggaga     5040

ggcggccgtt gggtctaagc ccctggaggc ctcgacggtt acaggcctag cctcccgcga     5100

gctaaggcac agtttaactt cgtgctgcgg cttccttagg aaactttgag tatcttcgtt     5160

ttagcgtggg aggacatctt ttgggatgaa ccggctcagt ccttgagctc accccaaaga     5220

tgatgaaatt gaaactcaga ggaaaggatt tttacaggac cacgccccgg gctttgaacc     5280

cgtttttccc aaccccgagc attttctatt aagcgttctg tttcaattat tttattcgtt     5340

cagttaattc gttcttggcg tcataagtat atgcccgccg ttgttctggc cgtagctatc     5400

tagcagccac tccgcgagtc gttcatttaa caaatactta ctctgtgtca gggatatgaa     5460

gatgggtaat accaggtgcc tgtcctcact gtgtgagtgg ttctctagcc agacatgagg     5520

agggatccta ttgtttccca tagctaggca gcctaagaga gtaggggaaa gagctggctc     5580

cagatgaaaa gggcaccatc tccagctctt ggaagcagag agggtggtcc tttggattcc     5640

cagtggcagc agcaaccaac ctggccctta gtagtttcta agttacacca tgttaatgga     5700

taaaggaatt actcagcttg aagggatctg tttcctttac actggcctga tgtgtgggga     5760

gaaaggggcc aaaaagttta ggatttggag ttaacatcgt aatttctgct ttgttggtca     5820

gggtttacag cattaatgga caggttcacc ctgacctaca agtcggaacg tgacatggac     5880

aaactggccc atatcttcag ttattacatt agtgacatcg tggagcgtga gtgatcattg     5940

tagggtaaca aggtgtggtg ctgggctcct gggggtttat aaaagaaggg ggccagaagt     6000

actttaaaac aggtaccaaa gggtcattcc tttagcatca ttcatctttg gtttcttcaa     6060

gttgccactg aaaagctaga cctttgccta ttatctgcta atctacccag tctcacattc     6120

tattgactca ttgttcaaag ggggggcagg aggagctaat ttcctttgca catttgtatt     6180

ttatttcaaa ataaagtatt ctcttctaac aataacgtaa aaaaaaaaaa aaaaaa         6236


<210>  2354
<211>  4108
<212>  DNA
<213>  homo sapiens

<400>  2354
agtaatagca ggagcagcaa cagaaggcgt cggagcgggc gtcggagctg cccgctgtgg       60

gagagagagg agacagaaag agcgagcgag gagagggagc ccgaggcgaa aaagtaactg      120

tcaaatgcgc ggctccttta accggagcgc tcagtccggc tccgagagtc atggcgaccg      180

cagcgtctaa ccactacagc ctgctcacct ccagcgcctc catcgtgcac gccgagccgc      240

ccggcggcat gcagcagggc gcggggggct accgcgaagc gcagagcctg gtgcagggcg      300

actacggcgc tctgcagagc aacggacacc cgctcagcca cgctcaccag tggatcaccg      360

cgctgtccca cggcggcggc ggcgggggcg gtggcggcgg cggggggggc gggggcggcg      420

gcgggggcgg cggcgacggc tccccgtggt ccaccagccc cctgggccag ccggacatca      480

agccctcggt ggtggtgcag cagggcggcc gcggagacga gctgcacggg ccaggcgccc      540

tgcagcagca gcatcagcag cagcaacagc aacagcagca gcaacagcag caacagcagc      600

agcagcagca gcaacagcgg ccgccgcatc tggtgcacca cgccgctaac caccacccgg      660

gacccggggc atggcggagc gcggcggctg cagcgcacct cccaccctcc atgggagcgt      720

ccaacggcgg cttgctctac tcgcagccca gcttcacggt gaacggcatg ctgggcgccg      780

gcgggcagcc ggccggtctg caccaccacg gcctgcggga cgcgcacgac gagccacacc      840

atgccgacca ccacccgcac ccgcactcgc acccacacca gcagccgccg cccccgccgc      900

ccccgcaggg tccgcctggc cacccaggcg cgcaccacga cccgcactcg gacgaggaca      960

cgccgacctc ggacgacctg gagcagttcg ccaagcagtt caagcagcgg cggatcaaac     1020

tgggatttac ccaagcggac gtggggctgg ctctgggcac cctgtatggc aacgtgttct     1080

cgcagaccac catctgcagg tttgaggccc tgcagctgag cttcaagaac atgtgcaagc     1140

tgaagccttt gttgaacaag tggttggagg aggcggactc gtcctcgggc agccccacga     1200

gcatagacaa gatcgcagcg caagggcgca agcggaaaaa gcggacctcc atcgaggtga     1260

gcgtcaaggg ggctctggag agccatttcc tcaaatgccc caagccctcg gcccaggaga     1320

tcacctccct cgcggacagc ttacagctgg agaaggaggt ggtgagagtt tggttttgta     1380

acaggagaca gaaagagaaa aggatgaccc ctcccggagg gactctgccg ggcgccgagg     1440

atgtgtacgg ggggagtagg gacactccac cacaccacgg ggtgcagacg cccgtccagt     1500

gaactcgagc tgggggaggg gcagagcgcg gggctccccc tccccttcgg tccttggccc     1560

tttcccggcc ctcttgttcc ctctctaact tctgattgtt cttttatttt taattattat     1620

ttccccgtcc cttaaaaaga caaaaaaaat aaggcaaaag gaaagcaact aagacactgg     1680

actatccttt aaaggtagca ggtgtaatga tgtgttttga cctttgcagg cgagtaacca     1740

ggcaatggag tggagtgtct cctggagaga gtgaggagag tgtgtgatag ctagaaagag     1800

agagagacag agagatggca agcactgaga taaatacctg gcaaaactaa ataaattacc     1860

aaaaaggaaa aaaaatccac caaaccatga taaacacaaa atgcagcttc ctgatgctta     1920

gagttggcac atgctgctgt gtttatttat tgtggattcc catcaggaaa gaggaaaaaa     1980

tacacatgtt ctttcatata ggcaaaattt aaccacataa atttgcactg caagaaaatt     2040

gaagtttacg tgaacaaatt catgagcata ttttctcttt ctccccaccg ttaatttggg     2100

agttgccgtt ttgggggatt ttgttttgct ttgctttatt catcggagag agttgaagcc     2160

agctcttggc cactctccat ttctaatgtt cttgtgttgc cccttcttcg tactgtttgt     2220

gaactttggt taccttcaca ttccccttac gagggtgtaa catctatttg ttcctcttac     2280

caaagcaaaa ggattggctt catacaaaat agacaattct ctgatttcag gaaatgtgca     2340

tggtctaccc gctttatcga aggcaagaat ccggtttgga atataaaaat aagcattggt     2400

tgttcttacc agccacaaag taaacttcat tttcaggcag tgtttctggg ggaggttatg     2460

gagggaagaa aaaagaaaaa tcgatagtga gtgactgatt gcttcatttt atcaggcggg     2520

cccattgtga aagagctcag gggaaatgtg gaggttaaat atatttccag agttgtccag     2580

cagaaagaaa gtggcacttt gaagagaact agggaagtac atatcttcag atatccctat     2640

atagttctct accttcagtt ttagtaacaa ttatgaagaa ttatttgtgc tgacagcagc     2700

agttaaactt tgtttctcta atagcttttt ttttacataa aaaaagaccc aggaacttaa     2760

tagtgtatgc ataagactgt gttttttagc acacagatac ccacagcata cactgacgat     2820

ctccacgcag tagacaggtt ttgtcttcac tagctcattt gtttatcaag tcatatttag     2880

ggtcccacac cctcttttcc tgtaatttat tgcagaatac accactttga cttggacagc     2940

tttctgcccc ctctttcact aaggaaggca aatgaagtga aaaaaaaaaa tgccattttc     3000

aatccttcct ttctcccctt tgttaatagt tttaagtgaa tttttgacct tatcttaatg     3060

gaaaacggtt aactccaaac acaaaagact ctactggaaa gtgtaggtga aaaaacttgt     3120

aactgtattg aaaataaata ccattaaact gtgatcagtt aaaatttaaa agaaaaatca     3180

gcacaaaagg gcgctaaaag ggaaaacact ttttattaat cttaaaagtt tgggggtttt     3240

tttccagtta ggtattagat aaatttttat tttaaaaaat gaaagtctca ctaccataaa     3300

attatggttc agcatcagat tagcattgca ctcagtagtc tttaaggttt taggaaatat     3360

gctttatatt gtcttttcaa acacctgtga ttgtttcatt ttccatgttt ttgcaagata     3420

aatggtgact tataatgggc atatttattt gcctgtattt catttccccc aatgaatgtc     3480

acaaggagat gggcacggag ctgcttcggg tgcatcacgc tgctcgttcc tgaggtatgg     3540

gaactggcct ttagtgaagc tatccagagc agggcaaata gccactggta aagggaggaa     3600

atgaatttcc agatacttat taccaagtag gtaaggtcag aagctggagt tcagagaatg     3660

tgtctacagc ttctctgact cttataggtt tactaagatg aaagttacca ctgaacctta     3720

ccactatgta tatatgttta atatctgtct tttgaaatgc agaaatagtt taaatgtttc     3780

tttgtctatt tttctttttt tttaatgcta cccagggaaa tattttcata tcatttttaa     3840

gtggcctgcc tcaatgtata tttatttctt ttgaaacaaa aaggttctgg aaactgtttt     3900

tctgtagctt taaatgaata ggtgagcaaa atctatatgg gatgtaattt ttttgttcag     3960

tctcttaaaa aatactttgt tttggtacat ttggttgtgc ttgtggggaa aataaaaacg     4020

cagagatcct tatatattta tgttaaagta atattttatt atctacataa aacagaaatg     4080

cacaataaaa aaaaaaaaaa aaaaaaaa                                        4108


<210>  2355
<211>  4551
<212>  DNA
<213>  homo sapiens

<400>  2355
atcgccggag acgcctgcgg cggccccgga gacaccggaa ggagccgcgg ctgctgcggg       60

aagtggccag ttcaggaggc ggaccccccg agggcagcgc tgcggggccg ttttccggcc      120

ctcctgacgc gacactgccc ctctccgaga gctgagaagg aaaagaggag cttgcggagg      180

tgcggctgca ggccgttgtt ggtcgagctg gcgggtcccg cgggccaggc cgtggagagc      240

tcctgaagga agcactaaac atggaaagga acaaccggta ccagccactg caaaaacatg      300

ccaaattgta aagaccatcg atgttaggaa gaaactgcct caactaatga gcaaaataac      360

cagctaacat cgtaatgaca ggatcaaatt cacacataac gatattaacc ttaaaggtgt      420

tacctcattt tgaaagtctt gggaaacagg aaaaaattcc taacaaaatg tcagcttttc      480

gaaatcattg tccacatttg gattcagttg gtgaaataac aaaagaagat ttgatacaaa      540

aatcccttgg tacttgtcag gattgtaaag tccaaggacc aaatctttgg gcatgtctgg      600

agaatagatg ttcatatgtt ggctgtggtg aatcacaagt agatcacagc accatacatt      660

ctcaggagac aaagcattat ctaactgtga accttaccac tcttcgagta tggtgttatg      720

cttgcagcaa agaagtattt ttggatagga aattaggaac tcagccttca ttgcctcatg      780

taagacaacc tcaccaaata caagaaaaca gtgtccagga ttttaaaata cccagtaata      840

caacattaaa aactcctctg gttgccgtat ttgatgatct ggatatagaa gcggatgaag      900

aagatgaact tagggccaga ggtcttacag gtttgaaaaa tattggaaat acttgttaca      960

tgaatgcagc tttgcaggct ctttctaatt gcccaccttt gacacagttt tttcttgatt     1020

gtggaggact agctcgaaca gataagaaac ctgccatttg taaaagttat ctcaaactaa     1080

tgacagagct gtggcataaa agcaggccag gatctgttgt gcctactact ctgtttcaag     1140

gaattaaaac tgtaaatcca acatttcggg ggtattctca gcaggatgct caagaattcc     1200

ttcgatgttt aatggatttg cttcatgaag aattgaaaga gcaagtcatg gaagtagaag     1260

aagatccgca aaccataacc actgaggaga caatggaaga agacaagagc cagtcggatg     1320

tagattttca gtcttgtgaa tcttgtagca acagtgatag agcagaaaat gaaaatggct     1380

ctagatgctt ttctgaagat aataatgaaa caacaatgtt aattcaggat gatgaaaaca     1440

attcagaaat gtcaaaggat tggcaaaaag agaagatgtg caataagatt aataaagtaa     1500

attctgaagg cgaatttgat aaagatagag actctatatc tgaaacagtc gacttaaaca     1560

accaggaaac tgtcaaagtg caaatacaca gcagagcttc agaatatatc actgatgtcc     1620

attcgaatga cctgtctaca ccacagatcc ttccatcaaa tgaaggtgtt aatccacgtt     1680

tatcggcaag ccctcctaaa tcaggcaatt tgtggccagg attggcacca ccacacaaaa     1740

aagctcagtc tgcatctcca aagagaaaaa aacagcacaa gaaatacaga agtgttattt     1800

cagacatatt tgatggaaca atcattagtt cagtgcagtg tctgacttgt gacagggtgt     1860

ctgtaaccct cgagaccttt caagatctgt ccttgccaat tcctggcaag gaagaccttg     1920

ctaagctgca ttcatcaagt catccaactt ctatagtcaa agcaggatca tgtggcgaag     1980

catatgctcc acaagggtgg atagcttttt tcatggaata tgtgaagagg tttgttgtct     2040

catgtgtccc tagctggttt tggggtccag tagtaacctt gcaagattgt cttgctgcct     2100

tctttgccag agatgaacta aaaggtgaca atatgtacag ttgtgaaaaa tgcaaaaagt     2160

tgagaaatgg agtgaagttt tgtaaagtac aaaactttcc tgagattttg tgcatccacc     2220

ttaaaagatt cagacatgaa ctaatgtttt ccaccaaaat cagtacccat gtttcatttc     2280

cgctagaagg cttggatctt cagccatttc ttgctaagga tagtccagct caaattgtga     2340

catatgatct tctgtcagtc atttgccatc atggaactgc aagtagtgga cactatatag     2400

cctactgccg aaacaatcta aataatctct ggtatgaatt tgatgatcag agtgtcactg     2460

aagtttcaga atctactgta caaaatgcag aagcttacgt tcttttctat aggaagagca     2520

gcgaagaggc acaaaaagag aggagaagga tatcaaattt attgaacata atggaaccaa     2580

gcctccttca gttttatatt tctcgacagt ggcttaataa atttaagacc tttgccgaac     2640

ctggccctat ttcaaataat gactttcttt gtattcatgg aggtgttcct ccaagaaaag     2700

ctggttatat tgaagacctg gttttgatgc tgcctcagaa catttgggat aacctatata     2760

gcaggtatgg tggaggacca gctgtcaacc atctgtacat ttgtcatact tgccaaattg     2820

aggcggagaa aattgaaaaa agaagaaaaa ctgaattgga aatttttatt cggcttaaca     2880

gagcgttcca aaaagaggac tctccagcta ctttttattg catcagtatg cagtggttta     2940

gagaatggga aagttttgtg aagggtaaag atggagatcc tccaggtcct attgacaata     3000

ctaagattgc agtcactaaa tgtggtaatg tgatgcttag gcaaggagca gattctggcc     3060

agatttctga agaaacatgg aattttctgc agtctattta tggtggaggg cctgaagtta     3120

tcctgcgacc tccggttgtt catgttgatc cagatatact tcaagcagaa gaaaaaattg     3180

aagtagaaac tcggtctttg taatttttag gatgtagaga gttctaatga ggaatcattt     3240

tcatgtgccc tgacatgtac acatgcgaaa acattcctaa aagcgtgttt atttgcttta     3300

ttttttttca tcatttatcc catttatttc ttcttagtgg gcattatgga agaatatatt     3360

aaaatgtgta atataccaca ggttggtata tttagtttta aatacttacc ataaagtctt     3420

tcagtgtaat ttttttttga gacagagtct tgctttgtca cccaggctgg agtgctgtgg     3480

tgttacctca gctcactgca gcctccacct cctgggttca agcgattctc ctgcctcagc     3540

ctctcgagta gctgggatta caggcacctg ccaccatgcc cggctaattt ttgtatttta     3600

gtagagatgg ggtttcacca tgttggccag gctagtctca aactcctgac ctcaggtgat     3660

ccacccacct cggcctccca aagtgctggg attacaggtg tgagccacag cgcctggccc     3720

agtgtaatat ttttgaaaga ggagggacaa ttgtgaaatc agtaggttat ctttaatctt     3780

tacactacat gcagatccat agtatccttt gtagtgttgt aaatactttt gctttgaaaa     3840

ctttttcatt gtcctaaatc accctgactc tgaccagtct ttcagttctc caaaagccca     3900

atttaattgt atagttttgt catggcttca tataataaag agcctatttt aagttgaaag     3960

tagtagtcag aaaattgtta atttcctaaa gctcaggaaa ctagggtgtc actttttttg     4020

cactgcagca tatacactaa ctagcttatt aaaatttaca aaatgtcttt ttgaatgtat     4080

caaggatata tttagtttga gtggaatttg tcagcagata tcagtaactt attgccgctt     4140

atattgtaca atgttaaact tcaattcctg taacctggtt agtattaatg tcagtgacta     4200

aaaaacttag agttagtttt agggcacttt ttattttgag agcatgaagt gtggaatgtg     4260

tcactacgat tgttgataaa gctgaggcca cttgcaactt gattttttaa atgaaataga     4320

taaagtcttt ttgaataata tagtatgcac tgctatttgc ttgattatgt aatgtcaaaa     4380

gtttaactat attccaagta caaaaacata ctggattaca ttgaggatgt tgaatagcat     4440

tcatgatggc tttgttttgg tttggggcag ctgtcaccag ctaaagcaat gttgttaaaa     4500

ttagctcaat aaaaatgtct ttaaaatgta aaaaaaaaaa aaaaaaaaaa a              4551


<210>  2356
<211>  4372
<212>  DNA
<213>  homo sapiens

<400>  2356
atcgccggag acgcctgcgg cggccccgga gacaccggaa ggagccgcgg ctgctgcggg       60

aagtggccag ttcaggaggc ggaccccccg agggcagcgc tgcggggccg ttttccggcc      120

ctcctgacgc gacactgccc ctctccgaga gctgagaagg aaaagaggag cttgcggagg      180

tgcggctgca ggccgttgtt ggtcgagctg gcgggtcccg cgggccaggc cgtggaggtg      240

ttacctcatt ttgaaagtct tgggaaacag gaaaaaattc ctaacaaaat gtcagctttt      300

cgaaatcatt gtccacattt ggattcagtt ggtgaaataa caaaagaaga tttgatacaa      360

aaatcccttg gtacttgtca ggattgtaaa gtccaaggac caaatctttg ggcatgtctg      420

gagaatagat gttcatatgt tggctgtggt gaatcacaag tagatcacag caccatacat      480

tctcaggaga caaagcatta tctaactgtg aaccttacca ctcttcgagt atggtgttat      540

gcttgcagca aagaagtatt tttggatagg aaattaggaa ctcagccttc attgcctcat      600

gtaagacaac ctcaccaaat acaagaaaac agtgtccagg attttaaaat acccagtaat      660

acaacattaa aaactcctct ggttgccgta tttgatgatc tggatataga agcggatgaa      720

gaagatgaac ttagggccag aggtcttaca ggtttgaaaa atattggaaa tacttgttac      780

atgaatgcag ctttgcaggc tctttctaat tgcccacctt tgacacagtt ttttcttgat      840

tgtggaggac tagctcgaac agataagaaa cctgccattt gtaaaagtta tctcaaacta      900

atgacagagc tgtggcataa aagcaggcca ggatctgttg tgcctactac tctgtttcaa      960

ggaattaaaa ctgtaaatcc aacatttcgg gggtattctc agcaggatgc tcaagaattc     1020

cttcgatgtt taatggattt gcttcatgaa gaattgaaag agcaagtcat ggaagtagaa     1080

gaagatccgc aaaccataac cactgaggag acaatggaag aagacaagag ccagtcggat     1140

gtagattttc agtcttgtga atcttgtagc aacagtgata gagcagaaaa tgaaaatggc     1200

tctagatgct tttctgaaga taataatgaa acaacaatgt taattcagga tgatgaaaac     1260

aattcagaaa tgtcaaagga ttggcaaaaa gagaagatgt gcaataagat taataaagta     1320

aattctgaag gcgaatttga taaagataga gactctatat ctgaaacagt cgacttaaac     1380

aaccaggaaa ctgtcaaagt gcaaatacac agcagagctt cagaatatat cactgatgtc     1440

cattcgaatg acctgtctac accacagatc cttccatcaa atgaaggtgt taatccacgt     1500

ttatcggcaa gccctcctaa atcaggcaat ttgtggccag gattggcacc accacacaaa     1560

aaagctcagt ctgcatctcc aaagagaaaa aaacagcaca agaaatacag aagtgttatt     1620

tcagacatat ttgatggaac aatcattagt tcagtgcagt gtctgacttg tgacagggtg     1680

tctgtaaccc tcgagacctt tcaagatctg tccttgccaa ttcctggcaa ggaagacctt     1740

gctaagctgc attcatcaag tcatccaact tctatagtca aagcaggatc atgtggcgaa     1800

gcatatgctc cacaagggtg gatagctttt ttcatggaat atgtgaagag gtttgttgtc     1860

tcatgtgtcc ctagctggtt ttggggtcca gtagtaacct tgcaagattg tcttgctgcc     1920

ttctttgcca gagatgaact aaaaggtgac aatatgtaca gttgtgaaaa atgcaaaaag     1980

ttgagaaatg gagtgaagtt ttgtaaagta caaaactttc ctgagatttt gtgcatccac     2040

cttaaaagat tcagacatga actaatgttt tccaccaaaa tcagtaccca tgtttcattt     2100

ccgctagaag gcttggatct tcagccattt cttgctaagg atagtccagc tcaaattgtg     2160

acatatgatc ttctgtcagt catttgccat catggaactg caagtagtgg acactatata     2220

gcctactgcc gaaacaatct aaataatctc tggtatgaat ttgatgatca gagtgtcact     2280

gaagtttcag aatctactgt acaaaatgca gaagcttacg ttcttttcta taggaagagc     2340

agcgaagagg cacaaaaaga gaggagaagg atatcaaatt tattgaacat aatggaacca     2400

agcctccttc agttttatat ttctcgacag tggcttaata aatttaagac ctttgccgaa     2460

cctggcccta tttcaaataa tgactttctt tgtattcatg gaggtgttcc tccaagaaaa     2520

gctggttata ttgaagacct ggttttgatg ctgcctcaga acatttggga taacctatat     2580

agcaggtatg gtggaggacc agctgtcaac catctgtaca tttgtcatac ttgccaaatt     2640

gaggcggaga aaattgaaaa aagaagaaaa actgaattgg aaatttttat tcggcttaac     2700

agagcgttcc aaaaagagga ctctccagct actttttatt gcatcagtat gcagtggttt     2760

agagaatggg aaagttttgt gaagggtaaa gatggagatc ctccaggtcc tattgacaat     2820

actaagattg cagtcactaa atgtggtaat gtgatgctta ggcaaggagc agattctggc     2880

cagatttctg aagaaacatg gaattttctg cagtctattt atggtggagg gcctgaagtt     2940

atcctgcgac ctccggttgt tcatgttgat ccagatatac ttcaagcaga agaaaaaatt     3000

gaagtagaaa ctcggtcttt gtaattttta ggatgtagag agttctaatg aggaatcatt     3060

ttcatgtgcc ctgacatgta cacatgcgaa aacattccta aaagcgtgtt tatttgcttt     3120

attttttttc atcatttatc ccatttattt cttcttagtg ggcattatgg aagaatatat     3180

taaaatgtgt aatataccac aggttggtat atttagtttt aaatacttac cataaagtct     3240

ttcagtgtaa tttttttttg agacagagtc ttgctttgtc acccaggctg gagtgctgtg     3300

gtgttacctc agctcactgc agcctccacc tcctgggttc aagcgattct cctgcctcag     3360

cctctcgagt agctgggatt acaggcacct gccaccatgc ccggctaatt tttgtatttt     3420

agtagagatg gggtttcacc atgttggcca ggctagtctc aaactcctga cctcaggtga     3480

tccacccacc tcggcctccc aaagtgctgg gattacaggt gtgagccaca gcgcctggcc     3540

cagtgtaata tttttgaaag aggagggaca attgtgaaat cagtaggtta tctttaatct     3600

ttacactaca tgcagatcca tagtatcctt tgtagtgttg taaatacttt tgctttgaaa     3660

actttttcat tgtcctaaat caccctgact ctgaccagtc tttcagttct ccaaaagccc     3720

aatttaattg tatagttttg tcatggcttc atataataaa gagcctattt taagttgaaa     3780

gtagtagtca gaaaattgtt aatttcctaa agctcaggaa actagggtgt cacttttttt     3840

gcactgcagc atatacacta actagcttat taaaatttac aaaatgtctt tttgaatgta     3900

tcaaggatat atttagtttg agtggaattt gtcagcagat atcagtaact tattgccgct     3960

tatattgtac aatgttaaac ttcaattcct gtaacctggt tagtattaat gtcagtgact     4020

aaaaaactta gagttagttt tagggcactt tttattttga gagcatgaag tgtggaatgt     4080

gtcactacga ttgttgataa agctgaggcc acttgcaact tgatttttta aatgaaatag     4140

ataaagtctt tttgaataat atagtatgca ctgctatttg cttgattatg taatgtcaaa     4200

agtttaacta tattccaagt acaaaaacat actggattac attgaggatg ttgaatagca     4260

ttcatgatgg ctttgttttg gtttggggca gctgtcacca gctaaagcaa tgttgttaaa     4320

attagctcaa taaaaatgtc tttaaaatgt aaaaaaaaaa aaaaaaaaaa aa             4372


<210>  2357
<211>  2956
<212>  DNA
<213>  homo sapiens

<400>  2357
atcgccggag acgcctgcgg cggccccgga gacaccggaa ggagccgcgg ctgctgcggg       60

aagtggccag ttcaggaggc ggaccccccg agggcagcgc tgcggggccg ttttccggcc      120

ctcctgacgc gacactgccc ctctccgaga gctgagaagg aaaagaggag cttgcggagg      180

tgcggctgca ggccgttgtt ggtcgagctg gcgggtcccg cgggccaggc cgtggagagc      240

tcctgaagga agcactaaac atggaaagga acaaccggta ccagccactg caaaaacatg      300

ccaaattgta aagaccatcg atgttaggaa gaaactgcct caactaatga gcaaaataac      360

cagctaacat cgtaatgaca ggatcaaatt cacacataac gatattaacc ttaaaggtgt      420

tacctcattt tgaaagtctt gggaaacagg aaaaaattcc taacaaaatg tcagcttttc      480

gaaatcattg tccacatttg gattcagttg gtgaaataac aaaagaagat ttgatacaaa      540

aatcccttgg tacttgtcag gattgtaaag tccaaggacc aaatctttgg gcatgtctgg      600

agaatagatg ttcatatgtt ggctgtggtg aatcacaagt agatcacagc accatacatt      660

ctcaggagac aaagcattat ctaactgtga accttaccac tcttcgagta tggtgttatg      720

cttgcagcaa agaagtattt ttggatagga aattaggaac tcagccttca ttgcctcatg      780

taagacaacc tcaccaaata caagaaaaca gtgtccagga ttttaaaata cccagtaata      840

caacattaaa aactcctctg gttgccgtat ttgatgatct ggatatagaa gcggatgaag      900

aagatgaact tagggccaga ggtcttacag gtttgaaaaa tattggaaat acttgttaca      960

tgaatgcagc tttgcaggct ctttctaatt gcccaccttt gacacagttt tttcttgatt     1020

gtggaggact agctcgaaca gataagaaac ctgccatttg taaaagttat ctcaaactaa     1080

tgacagagct gtggcataaa agcaggccag gatctgttgt gcctactact ctgtttcaag     1140

gaattaaaac tgtaaatcca acatttcggg ggtattctca gcaggatgct caagaattcc     1200

ttcgatgttt aatggatttg cttcatgaag aattgaaaga gcaagtcatg gaagtagaag     1260

aagatccgca aaccataacc actgaggaga caatggaaga agacaagagc cagtcggatg     1320

tagattttca gtcttgtgaa tcttgtagca acagtgatag agcagaaaat gaaaatggct     1380

ctagatgctt ttctgaagat aataatgaaa caacaatgtt aattcaggat gatgaaaaca     1440

attcagaaat gtcaaaggat tggcaaaaag agaagatgtg caataagatt aataaagtaa     1500

attctgaagg cgaatttgat aaagatagag actctatatc tgaaacagtc gacttaaaca     1560

accaggaaac tgtcaaagtg caaatacaca gcagagcttc agaatatatc actgatgtcc     1620

attcgaatga cctgtctaca ccacagatcc ttccatcaaa tgaaggtgtt aatccacgtt     1680

tatcggcaag ccctcctaaa tcaggcaatt tgtggccagg attggcacca ccacacaaaa     1740

aagctcagtc tgcatctcca aagagaaaaa aacagcacaa gaaatacaga agtgttattt     1800

cagacatatt tgatggaaca atcattagtt cagtgcagtg tctgacttgt gacagggtgt     1860

ctgtaaccct cgagaccttt caagatctgt ccttgccaat tcctggcaag gaagaccttg     1920

ctaagctgca ttcatcaagt catccaactt ctatagtcaa agcaggatca tgtggcgaag     1980

catatgctcc acaagggtgg atagcttttt tcatggaata tgtgaagagc tggttttggg     2040

gtccagtagt aaccttgcaa gattgtcttg ctgccttctt tgccagagat gaactaaaag     2100

gtgacaatat gtacagttgt gaaaaatgca aaaagttgag aaatggagtg aagttttgta     2160

aagtacaaaa ctttcctgag attttgtgca tccaccttaa aagattcaga catgaactaa     2220

tgttttccac caaaatcagt acccatgttt catttccgct agaaggcttg gatcttcagc     2280

catttcttgc taaggatagt ccagctcaaa ttgtgacata tgatcttctg tcagtcattt     2340

gccatcatgg aactgcaagt agtggacact atatagccta ctgccgaaac aatctaaata     2400

atctctggta tgaatttgat gatcagagtg tcactgaagt ttcagaatct actgtacaaa     2460

atgcagaagc ttacgttctt ttctatagga agagcagcga agaggcacaa aaagagagga     2520

gaaggatatc aaatttattg aacataatgg aaccaagcct ccttcagttt tatatttctc     2580

gacagtggct taataaattt aagacctttg ccgaacctgg ccctatttca aataatgact     2640

ttctttgtat tcatggaggt gttcctccaa gaaaagctgg ttatattgaa gacctggttt     2700

tgatgctgcc tcagaacatt tgggataacc tatatagcag gtatggtgga ggaccagctg     2760

tcaaccatct gtacatttgt catacttgcc aaattgaggc ggagaaaatt gaaaaaagaa     2820

gaaaaactga attggaaatt tttattcggg taaaaaagtg atgcttttca aattgatcta     2880

ggataaagat gaagacctga caattatcag agttatatga tattaataaa atgattagat     2940

gaaaaaaaaa aaaaaa                                                     2956


<210>  2358
<211>  2067
<212>  DNA
<213>  homo sapiens

<400>  2358
aggcctattt ccggtaggaa tcagtggact tggcggcaga ggcagtgcgg atccggcgtt       60

ctccactgat cttttccaag gctgtacaga catggcggcg gcttttcgga aggcggctaa      120

gtcccggcag cgggaacaca gagagcgaag ccagcctggc tttcgaaaac atctgggcct      180

gctggagaaa aagaaagatt acaaacttcg tgcagatgac taccgtaaaa aacaagaata      240

cctcaaagct cttcggaaga aggctcttga aaaaaatcca gatgaattct actacaaaat      300

gactcgggtt aaactccagg atggagtaca tattattaag gagactaagg aagaagtaac      360

cccagaacaa ctaaagctga tgagaactca ggacgtcaaa tatatagaaa tgaagagggt      420

tgcagaagct aagaaaatcg aaagactaaa atcagagctc catctgctgg atttccaggg      480

gaagcaacag aacaagcatg tgttcttttt tgacaccaaa aaggaagttg aacagtttga      540

tgtcgcaact cacctgcaaa cagccccgga gctagtcgac agagtcttta ataggcccag      600

gatagagacc ttgcagaaag aaaaagtgaa aggagttacc aatcagactg gacttaagcg      660

aatagctaaa gaaaggcaaa agcagtataa ctgcctgaca cagcggattg aacgagagaa      720

gaaattgttc gttattgctc agaaaattca aacacgcaaa gatcttatgg ataaaactca      780

gaaagtgaag gtgaagaaag aaacggtgaa ctccccagct atttataaat ttcagagtcg      840

tcgaaaacgt tgacgtgtta tagataagcc ttgtcattct gtatcaaaaa tctgttgtcg      900

ttttctagta acttcaaatt ccattactcc aaatggcatg gttttccggt ttgtaaccat      960

aactaaattg tcagtctgac atttaatgtc tttctatgga caacattaaa tctccctccc     1020

ttctgtaatt gtttttggat tgtgaaatta gtcttatttt tatatactta attttttttt     1080

tctttgagat agggtctttg ttgccaggct ggaagtgcag tgtgtgatta tggctcactg     1140

caactttgaa ctcctgggct caagtgatct tcctgcatca gcctcttgag tagctgggac     1200

cacagacatg tgccaccatg tctgagtaat gtttaaattt tctgtagaga ccaggttttg     1260

ccatgttggc caggctggtt ttgaactcgt ggcctcaagc gatcctccca ccttggcctc     1320

ccaaagggct gggattacag ggatgagcca ctatgcccag cccataattt tttttgttat     1380

gaaacatagg atctcattac agcagatttg gaaagtagat taattcattc ctaatcccag     1440

tgcttattca ataataacaa atatttattg catgcttaac tgtgctagga gctagagctg     1500

tggaggtgga caattactgt gagtagtcta gttgatttcc tccattttgt aaaacgaggc     1560

atcacttttt gtccatgttt ttgtgtttta tagttacagt aaacaatttg atgtcctact     1620

tttttttttt ttttttttga gacggagtct cgctctgtcg cccaggccgg actgcggact     1680

gcagtggcgc aatctcggct cactgcaagc tccgcttccc gggttcacgc cattctcctg     1740

cctcagcctc ccgagtagct gggactacag gcgcccgcca ccgcgcctgg ctaatttttt     1800

tttgtatttt tttagtagag acggggtttc accttgttag ccaggatggt ctcgatctcc     1860

tgacctcatg atccacccgc ctcggcctcc caaagtgctg ggattacagg cgtgagccac     1920

cgcgcccggc cgatgtccta ctttttaatt aaatcattag ctctttccca gtttgttaca     1980

tcacaaaagt tttttacagt aatatatgct agagtaaacg ttaaaataaa tattattttt     2040

aatgattgca aaaaaaaaaa aaaaaaa                                         2067


<210>  2359
<211>  2067
<212>  DNA
<213>  homo sapiens

<400>  2359
aggcctattt ccggtaggaa tcagtggact tggcggcaga ggcagtgcgg atccggcgtt       60

ctccactgat cttttccaag gctgtacaga catggcggcg gcttttcgga aggcggctaa      120

gtcccggcag cgggaacaca gagagcgaag ccagcctggc tttcgaaaac atctgggcct      180

gctggagaaa aagaaagatt acaaacttcg tgcagatgac taccgtaaaa aacaagaata      240

cctcaaagct cttcggaaga aggctcttga aaaaaatcca gatgaattct actacaaaat      300

gactcgggtt aaactccagg atggagtaca tattattaag gagactaagg aagaagtaac      360

cccagaacaa ctaaagctga tgagaactca ggacgtcaaa tatatagaaa tgaagagggt      420

tgcagaagct aagaaaatcg aaagactaaa atcagagctc catctgctgg atttccaggg      480

gaagcaacag aacaagcatg tgttcttttt tgacaccaaa aaggaagttg aacagtttga      540

tgtcgcaact cacctgcaaa cagccccgga gctagtcgac agagtcttta ataggcccag      600

gatagagacc ttgcagaaag aaaaagtgaa aggagttacc aatcagactg gacttaagcg      660

aatagctaaa gaaaggcaaa agcagtataa ctgcctgaca cagcggattg aacgagagaa      720

gaaattgttc gttattgctc agaaaattca aacacgcaaa gatcttatgg ataaaactca      780

gaaagtgaag gtgaagaaag aaacggtgaa ctccccagct atttataaat ttcagagtcg      840

tcgaaaacgt tgacgtgtta tagataagcc ttgtcattct gtatcaaaaa tctgttgtcg      900

ttttctagta acttcaaatt ccattactcc aaatggcatg gttttccggt ttgtaaccat      960

aactaaattg tcagtctgac atttaatgtc tttctatgga caacattaaa tctccctccc     1020

ttctgtaatt gtttttggat tgtgaaatta gtcttatttt tatatactta attttttttt     1080

tctttgagat agggtctttg ttgccaggct ggaagtgcag tgtgtgatta tggctcactg     1140

caactttgaa ctcctgggct caagtgatct tcctgcatca gcctcttgag tagctgggac     1200

cacagacatg tgccaccatg tctgagtaat gtttaaattt tctgtagaga ccaggttttg     1260

ccatgttggc caggctggtt ttgaactcgt ggcctcaagc gatcctccca ccttggcctc     1320

ccaaagggct gggattacag ggatgagcca ctatgcccag cccataattt tttttgttat     1380

gaaacatagg atctcattac agcagatttg gaaagtagat taattcattc ctaatcccag     1440

tgcttattca ataataacaa atatttattg catgcttaac tgtgctagga gctagagctg     1500

tggaggtgga caattactgt gagtagtcta gttgatttcc tccattttgt aaaacgaggc     1560

atcacttttt gtccatgttt ttgtgtttta tagttacagt aaacaatttg atgtcctact     1620

tttttttttt ttttttttga gacggagtct cgctctgtcg cccaggccgg actgcggact     1680

gcagtggcgc aatctcggct cactgcaagc tccgcttccc gggttcacgc cattctcctg     1740

cctcagcctc ccgagtagct gggactacag gcgcccgcca ccgcgcctgg ctaatttttt     1800

tttgtatttt tttagtagag acggggtttc accttgttag ccaggatggt ctcgatctcc     1860

tgacctcatg atccacccgc ctcggcctcc caaagtgctg ggattacagg cgtgagccac     1920

cgcgcccggc cgatgtccta ctttttaatt aaatcattag ctctttccca gtttgttaca     1980

tcacaaaagt tttttacagt aatatatgct agagtaaacg ttaaaataaa tattattttt     2040

aatgattgca aaaaaaaaaa aaaaaaa                                         2067


<210>  2360
<211>  4298
<212>  DNA
<213>  homo sapiens

<400>  2360
gttgcggtgg ccaatagacg cattcggaac atcggcggct gcccgggtga cttggttata       60

tgtcacagaa taacattcga gaatgggaca tggaatgagg cgacggcccc agcaagcccc      120

agcagcccca gccccagccc caggcccagc agcagcagca gcagcccctg ctctcccgcc      180

gcccggagag gctctgcagc catgaagcca accgtcccga ggcaccgccg gtaagcaggg      240

agcctccgcg gagctcccgc cgccgctccc ccttggcgcc aaaggcaccc ggtcccggag      300

cagccacgcg cggcccgtga gcctcgccac cagcgggggc tcagaggagg aggacaaaga      360

cggcggggtg ctgttccacg tcaacaagag cggcttcccc atcgacagcc acacctggga      420

gcgcatgtgg atgcacgtgg ccaaggtgca ccctaagggg ggagaaatgg tgggcgccat      480

caggaacgcc gccttcttgg caaagccttc aataccccag gtcccaaact acaggctgtc      540

gatgacgatc ccagactggc tccaggcgat ccagaattac atgaagaccc tacaatataa      600

tcacacaggg acccagttct ttgaaattag gaaaatgaga ccgctgagtg ggttaatgga      660

aacagcaaaa gaaatgaccc gagagtcctt gcctatcaaa tgccttgaag ctgtcatcct      720

gggcatctac ttaaccaatg ggcagccttc cattgagcgg ttccccatca gctttaaaac      780

ctacttctca ggaaactact ttcaccacgt tgtgctgggg atttactgca atggccgcta      840

tggctcattg ggcatgagcc gcagggctga gctgatggac aagccattga cttttcggac      900

tctgagtgac ctcatctttg actttgagga ctcttacaag aaatacctgc acacagtcaa      960

gaaggtcaag attgggctgt acgtccccca tgagcctcat agcttccagc ccattgagtg     1020

gaagcagctg gtcctcaacg tctcaaagat gctgagggct gacataagga aggagctgga     1080

gaaatatgcc agggacatga gaatgaagat cctgaaacct gcaagtgccc actctccgac     1140

ccaagtgaga agccggggaa aatccctgtc ccccagaagg agacaggcaa gccccccgag     1200

gaggctcggc cggcgagaga agtcgcctgc actgcctgaa aagaaggtgg ctgatctgag     1260

cactctgaat gaagtgggct atcaaatccg aatttagcca agccataccg gccagcaaga     1320

gggtttctgt ggtgcttctc tctgcacttt acccagcatc ttcaggagga actgcaacta     1380

tttattaaga acttgtgaat tttattttta aggattcacc tggaaataga atctgagtgg     1440

gtggtaacca ttagctttaa aaaattcact aaaaggcacc atgaaaaggc tgaagtaata     1500

agccccactg gggttggact atgtccctca ctcaagatct taaggataac cgtaactgaa     1560

gttttatatt tttccattta cctactttct tttacttgct ttgaacatta tgcctcacca     1620

atagtaaatg ttcatgaaat aatctcttga acttttggta tagtaaggta actctaacag     1680

tattactgtc tttttcagca ataacagaaa gcaaaaatgg gtgggttttt tttaagcagt     1740

tattacctca gcattttgac atcagatatg caaacttaat ggcgttttgt ttttttatat     1800

tctatttgta ttctttcccc agtatttccc atggggatct ccacaagttt ggagtttttt     1860

cctggtgcac acacgtgagg agatttaagg tactatatgc aagtgtttta ctaaaaagca     1920

ctgaaattct tctggcaata caagaaccat tttcaggatc ttggagttac ttccttctta     1980

atctttctta aagcattcac tgatgttttt gttttttcaa aatgaaacaa aaatatcaca     2040

ttgagaagct agtctatgtt ctgtcactaa catttaaact ttgcagactc taacaaaaag     2100

cacaagaggt cacgtactat tatacaaatt tagcggtact ggatttacct ctgacattaa     2160

cacactcagg cagagaccag gagtgatcag caggtcttca gaaccaaaaa acctttctgt     2220

tcacatttca tctgattttt aaactgaggc aggctttgat tcttctgaag gatgccaaga     2280

atcaaactaa gggaggactc actgttaaag atgtgttctg atgtcttata ttaagaccaa     2340

atgtgacatg atgtgattat cttccagtac tttgctttta ggtaccattt catgacattt     2400

taggaatgag tattggaaaa tataaagaat tagaaaagca gcactttttt tttaatggaa     2460

aagtcttcgg tccagtgtta caccttatag tgtaattcag tccctaagca cagaatgaat     2520

gtctggcctg catatggtag ttacagtgta acctctggct gcagaccaca caggacaacc     2580

ctaacagcct agtcttgtat ggtgtaaata tcaagagtac agcttcaatt tcatttgctt     2640

tatcttagca acaatgccaa ctcaggagag cagacggccg atttcagtga agtctggtag     2700

tcaacagatg ttatttcagt ctcagtgcat ctcctctggc tttctttgac tgaaggtgtt     2760

tataggaagg aagttaaaaa aaaaaaaagc tcattgagat tctttaccaa ttctttacaa     2820

gatttctggg ggtgacaggg aaagcaaaag gacttcaaag caaaagggtg cacaagagct     2880

tacttcaccc tgaaaatcag tattattaat gaaaagtact gttttcttaa agaagtcgaa     2940

tgtcctttag atgaacaaga ccaagtatac atctccatta gattaaaatg tagcacaggg     3000

ttaaaaatta tcagtttaat ctctttaaga acagtattat cagagtttaa aatgagttag     3060

ctctgtttat ctacacacag caaacccatt cgcagcctct tggccacatg tattcagatg     3120

tttgaaatag tgaatcattt cattttcatt ctaaaacaat actgacttag ccatatacct     3180

tctgtttgtc aatctgaaac ttgcttacat ctaataagta gacctcttat aacactgcaa     3240

ccattctaag agttggaatt tatttttgcc aagtattaag tactgttaca tctaaaatac     3300

agaatgtcaa atggttgcat agcttgtttc ccacaacaag gaggaaaaga acaggaatac     3360

aaactctgta atatgctgat aaagaagcct tagaactgcc aactggcttg atggttcaat     3420

tagtaagcta atttctccca cacccgctcc ttgattttta gactaatttt cccaaagcaa     3480

ggtttagtca cacaaacttg aaagtacatt taaaatgttc ttagttgtca tcctactttt     3540

attgcctatg gaatatgcta atttctaaaa aaaatacggg agaggcacca aacccctaaa     3600

ttctagtgca ataatttaaa aaacaaaaaa caaaacaaaa caaaaaacat gttatatgca     3660

cccccctccc aaagctgatt ttaagactgg ctagaattca aaatataaaa aataaaacta     3720

tgaagtgatt tgaaatcggt tttaaaaagt tgttagtgca agagaaattt tatgtttaag     3780

ccatcatggc aatatatgca aagtttaaat gaatgacaga aatcttgatt ttagactgta     3840

tgttgtgctg ttttgagtac actttatttc ggagatattt agtattttct atacactctg     3900

aaatcatgag catttcactt tttctaagtc aattatttca taaggatttt attaatagat     3960

attggtaaat agaactttgg aaatcttaat tcagaattct tactatacct gagtcttttg     4020

taagctatag ttttatgtac aaccttgtac agtttttttg acatacaatt cagaactttg     4080

tttattctct tggactttgt tctggccaat acattttttt taaatcttta agaagaactg     4140

tgattgtttt agtgggtatt tttctaatta aatgaaaact tgtataatgg tattttagag     4200

aatgccagta agtgcatgtt tcaagttaat gtttttctca tcacttgtat gtttctaaca     4260

cagcatggga ctttaataaa accatcctgg aaacttaa                             4298


<210>  2361
<211>  3873
<212>  DNA
<213>  homo sapiens

<400>  2361
catctgcctg cccttctgcc atccgagcgc cctgactgcg ccacactgca ggccatggag       60

aatgagctgc cagtcccaca tacatctagc agtgcctgtg ccaccagcag taccagcggg      120

gccagtagca gcagtggctg caacaacagc agcagtggtg gaagtggccg ccccaccggg      180

ccccagattt ctgtgtacag tggtattcca gaccggcaga ccgtgcaggt gatccagcag      240

gccctgcaca gacagcccag cacggccgct cagtacctgc agcagatgta cgccgcccag      300

cagcagcacc tcatgctgca gaccgcggcg ctccagcagc agcacctcag cagcgcccag      360

ctccagagcc tggcagccgt acagcaggca agcctggtat ccaatagaca aggaagcact      420

tcaggcagca atgtgtctgc gcaggccccg gcccagtcat cttcgatcaa cctggcagcc      480

tccccagcag cagcccagct cctcaaccgg gcccagagtg tgaactctgc agcagcctca      540

ggcatcgctc agcaggctgt gctcttgggc aacacgtctt ccccagccct gactgcaagc      600

caagcacaga tgtatctgag ggcacagatg ctcatcttca cgcccacggc caccgtcgct      660

actgtgcagc ctgagctcgg cactggctcc cccgcccggc cccccacccc cgcccaggta      720

cagaacttga ccctccgaac acagcagaca ccagcggcag cagcctcggg ccccaccccc      780

actcagcctg tcctgcccag cttggccctg aaacccacgc cgggcggtag ccagcctctg      840

cctaccccag cacagagcag aaatactgct caggcttccc ctgcaggtgc caagcctggc      900

atagctgaca gtgtgatgga gccacacaag aaaggagatg gcaacagcag tgtgccaggg      960

agcatggaag gccgggctgg gctcagccgg acggttcctg ctgtggctgc ccaccccctc     1020

attgcaccag cctatgctca gctgcagcca caccagctcc tcccacagcc atcctcaaag     1080

cacctgcagc cccaatttgt gatccagcag cagccacagc cacaacagca gcagccgccg     1140

ccccagcagt cacggcctgt gctccaagct gagccccacc cccagctcgc ctcagtctct     1200

ccaagcgtgg ccctccagcc cagctcagag gcccatgcca tgccactagg cccggttaca     1260

cccgccctgc cactccagtg tcccactgcc aacctgcaca agcctggcgg cagtcagcag     1320

tgtcaccctc ccacacctga tactgggcct cagaatggac atcccgaggg cgtgccccac     1380

acccctcaac gcaggttcca gcacacttca gctgtcatct tacaactgca gcctgcttca     1440

ccaccccagc agtgtgtccc tgatgactgg aaagaagtgg caccagggga gaaaagtgtg     1500

cctgagacgc ggtctggccc atcaccacat cagcaggcta ttgtcactgc catgcctggt     1560

ggcctgcctg tacccacgag ccctaacatc cagccgtccc cagctcacga gacagggcag     1620

ggcattgttc atgcactgac cgacctcagc agccccggca tgacctcagg gaacggaaac     1680

tctgcctcca gcatcgccgg cactgccccc cagaatggtg agaataaacc accacaggcc     1740

attgtgaaac cccaaatcct gacgcatgtt atcgaagggt ttgtgatcca ggagggggcg     1800

gagcctttcc cggtgggacg ctcgtccctg ctggtgggga atctcaagaa gaagtatgca     1860

caggggttcc tgcctgagaa acttccacag caggatcaca ccaccaccac tgactcggag     1920

atggaggagc cctatctgca agaatccaaa gaggagggtg ctcccctcaa actcaagtgt     1980

gagctctgtg gccgggtgga ctttgcctat aagttcaagc gttccaagcg cttctgttcc     2040

atggcttgtg caaagaggta caacgtggga tgcaccaaac gggtgggact tttccactca     2100

gaccggagca agctgcagaa ggcaggagct gcgacccaca accgccgtcg ggccagcaaa     2160

gccagtctgc caccacttac caaggatacc aagaagcagc caacaggcac tgtgcccctt     2220

tcggttactg ctgctttgca gctaacacac agccaggaag actccagccg ttgctcagat     2280

aactcaagct atgaggaacc cttgtcaccc atctcagcca gctcatctac ttcccgccgg     2340

cgacaaggcc agcgggacct ggagctcccc gacatgcata tgcgggacct ggtgggcatg     2400

ggacaccact tcctgccaag tgagcccacc aagtggaatg tagaagacgt ctacgaattc     2460

atccgctctc tgccaggctg ccaggagata gcagaggaat tccgtgccca ggaaatcgac     2520

gggcaagccc tgctgctgct caaggaggac cacctgatga gcgccatgaa catcaagctg     2580

gggcccgccc tgaagatcta cgcccgcatc agcatgctca aggactccta gggctggtgg     2640

cagccaggat tctggcccag ggcgcctcct cccgactgag cagagccaga cagacattcc     2700

tgaggggccc agaaatgggg ccggttggag ggcaggggct ctccctaggg gcatagctgg     2760

tgaggaggtc tgggcacctc ctccatggct ctcaggggcc tttcatttct gtgggagggg     2820

cagagaggta ggtggcacag aagatggggc tttatgcttg taaatattga tagcactggc     2880

ttcctccaaa gtcccaatac tctagccccg ctctcttccc ctctttctgt cccccatttt     2940

ccagggggta tatggtcagg gctccccaac ctgagttggg ttacttcaag ggcagccagc     3000

aggcctggat ggaggcctag aaagcccttg ccttccttcc tcccacttct ttctccaggc     3060

ctggttaact cttccgttgt cagcttctcc cccttcagcc tgtttctgca gcagccaggg     3120

ttctcccccc tacaccctct gcaggtggag agagagaagc tgggcccagc cgggccgtgc     3180

ctgctggcac agacgcctta acgctgtgtg tatgactgtg tgactgtgtg ggagcctgga     3240

ctgacagata ggccaagggc tactctctgg catctccagg tgttttgtag caaacagcca     3300

cttagtgctt tgtcctggac tccactcagc ctcaggatgg ggaatagcca agaatggcag     3360

cctcagcgca gaggcaaggt cagaaagaga cggcgcttca gagtttcctt tccagacacc     3420

cctccccgca ctgtgaagtt cccctgaccg ccctcctggt tcacaaagag cattaagaaa     3480

gctgcggtgg tctgagcaac atagcccaaa gggctgagcc tcctggcctg cctgcccgcc     3540

caccctggga gtcccagtgg tgaggctcag agaactgcta aggggaaaga acagctggag     3600

tttctgttga tgtgaagaag gcagctcttg gcctcccact cccacacttc tttgcctata     3660

aatcttccta gcagcaattt gagctacctg aggaggaggc agggcagaaa gggcgagggc     3720

ctgcctctga cctgccgtgt cctttgcagg aaggaggtag gcacctttct gagcttattc     3780

tattccccac ccacaccccc aggcagggtt ggaaatgaag gactttttta acctttgttt     3840

tgttttttaa aaataaatct gtaaaatctg tct                                  3873


<210>  2362
<211>  1802
<212>  DNA
<213>  homo sapiens

<400>  2362
aaaaggccat tcctgagagc tctcctcacc aagaagcagc ttctccgctc cttctaggat       60

ctccgcctgg ttcggcccgc ctgcctccac tcctgcctct accatgtcca tcagggtgac      120

ccagaagtcc tacaaggtgt ccacctctgg cccccgggcc ttcagcagcc gctcctacac      180

gagtgggccc ggttcccgca tcagctcctc gagcttctcc cgagtgggca gcagcaactt      240

tcgcggtggc ctgggcggcg gctatggtgg ggccagcggc atgggaggca tcaccgcagt      300

tacggtcaac cagagcctgc tgagccccct tgtcctggag gtggacccca acatccaggc      360

cgtgcgcacc caggagaagg agcagatcaa gaccctcaac aacaagtttg cctccttcat      420

agacaaggta cggttcctgg agcagcagaa caagatgctg gagaccaagt ggagcctcct      480

gcagcagcag aagacggctc gaagcaacat ggacaacatg ttcgagagct acatcaacaa      540

ccttaggcgg cagctggaga ctctgggcca ggagaagctg aagctggagg cggagcttgg      600

caacatgcag gggctggtgg aggacttcaa gaacaagtat gaggatgaga tcaataagcg      660

tacagagatg gagaacgaat ttgtcctcat caagaaggat gtggatgaag cttacatgaa      720

caaggtagag ctggagtctc gcctggaagg gctgaccgac gagatcaact tcctcaggca      780

gctatatgaa gaggagatcc gggagctgca gtcccagatc tcggacacat ctgtggtgct      840

gtccatggac aacagccgct ccctggacat ggacagcatc attgctgagg tcaaggcaca      900

gtacgaggat attgccaacc gcagccgggc tgaggctgag agcatgtacc agatcaagta      960

tgaggagctg cagagcctgg ctgggaagca cggggatgac ctgcggcgca caaagactga     1020

gatctctgag atgaaccgga acatcagccg gctccaggct gagattgagg gcctcaaagg     1080

ccagagggct tccctggagg ccgccattgc agatgccgag cagcgtggag agctggccat     1140

taaggatgcc aacgccaagt tgtccgagct ggaggccgcc ctgcagcggg ccaagcagga     1200

catggcgcgg cagctgcgtg agtaccagga gctgatgaac gtcaagctgg ccctggacat     1260

cgagatcgcc acctacagga agctgctgga gggcgaggag agccggctgg agtctgggat     1320

gcagaacatg agtattcata cgaagaccac cagcggctat gcaggtggtc tgagctcggc     1380

ctatgggggc ctcacaagcc ccggcctcag ctacagcctg ggctccagct ttggctctgg     1440

cgcgggctcc agctccttca gccgcaccag ctcctccagg gccgtggttg tgaagaagat     1500

cgagacacgt gatgggaagc tggtgtctga gtcctctgac gtcctgccca agtgaacagc     1560

tgcggcagcc cctcccagcc tacccctcct gcgctgcccc agagcctggg aaggaggccg     1620

ctatgcaggg tagcactggg aacaggagac ccacctgagg ctcagcccta gccctcagcc     1680

cacctgggga gtttactacc tggggacccc ccttgcccat gcctccagct acaaaacaat     1740

tcaattgctt tttttttttg gtccaaaata aaacctcagc tagctctgcc aatgtcaaaa     1800

aa                                                                    1802


<210>  2363
<211>  5866
<212>  DNA
<213>  homo sapiens

<400>  2363
gggacctgga agcgccccag ccccgcagcg atcgcagatt cggctttcaa acaaaagagg       60

cgccccgggg ggtgggaccg ggacctcacc cggtcctcgc agagttgcgg ccgcccgccc      120

cttcagcccc ggctctccgt atgcgcatga gcagaggcgc ctccctctgt tcctcccaag      180

gctaaacttt ctaattccct tctttgggct cgggggctcc cggagcaggg cgagagctcg      240

cgtcgccgga aaggaagacg ggaagaaagg gcaggcggct cggcgggcgt cttctccact      300

cctctgccgc gtccccgtgg ctgcagggag ccggcatggg gcttctccag ttgctagctt      360

tcagtttctt agccctgtgc agagcccgag tgcgcgctca ggaacccgag ttcagctacg      420

gctgcgcaga aggcagctgc tatcccgcca cgggcgacct tctcatcggc cgagcacaga      480

agctttcggt gacctcgacg tgcgggctgc acaagcccga accctactgt atcgtcagcc      540

acttgcagga ggacaaaaaa tgcttcatat gcaattccca agatccttat catgagaccc      600

tgaatcctga cagccatctc attgaaaatg tggtcactac atttgctcca aaccgcctta      660

agatttggtg gcaatctgaa aatggtgtgg aaaatgtaac tatccaactg gatttggaag      720

cagaattcca ttttactcat ctcataatga ctttcaagac attccgtcca gctgctatgc      780

tgatagaacg atcgtccgac tttgggaaaa cctggggtgt gtatagatac ttcgcctatg      840

actgtgaggc ctcgtttcca ggcatttcaa ctggccccat gaaaaaagtc gatgacataa      900

tttgtgattc tcgatattct gacattgaac cctcaactga aggagaggtg atatttcgtg      960

ctttagatcc tgctttcaaa atagaagatc cttatagccc aaggatacag aatttattaa     1020

aaattaccaa cttgagaatc aagtttgtga aactgcatac tttgggagat aaccttctgg     1080

attccaggat ggaaatcaga gaaaagtatt attatgcagt ttatgatatg gtggttcgag     1140

gaaattgctt ctgctatggt catgccagcg aatgtgcccc tgtggatgga ttcaatgaag     1200

aagtggaagg aatggttcac ggacactgca tgtgcaggca taacaccaag ggcttaaact     1260

gtgaactctg catggatttc taccatgatt taccttggag acctgctgaa ggccgaaaca     1320

gcaacgcctg taaaaaatgt aactgcaatg aacattccat ctcttgtcac tttgacatgg     1380

ctgtttacct ggccacgggg aacgtcagcg gaggcgtgtg tgatgactgt cagcacaaca     1440

ccatggggcg caactgtgag cagtgcaagc cgttttacta ccagcaccca gagagggaca     1500

tccgagatcc taatttctgt gaacgatgta cgtgtgaccc agctggctct caaaatgagg     1560

gaatttgtga cagctatact gatttttcta ctggtctcat tgctggccag tgtcggtgta     1620

aattaaatgt ggaaggagaa cattgtgatg tttgcaaaga aggcttctat gatttaagca     1680

gtgaagatcc atttggttgt aaatcttgtg cttgcaatcc tctgggaaca attcctggag     1740

ggaatccttg tgattccgag acaggtcact gctactgcaa gcgtctggtg acaggacagc     1800

attgtgacca gtgcctgcca gagcactggg gcttaagcaa tgatttggat ggatgtcgac     1860

catgtgactg tgaccttggg ggagccttaa acaacagttg ctttgcggag tcaggccagt     1920

gctcatgccg gcctcacatg attggacgtc agtgcaacga agtggaacct ggttactact     1980

ttgccaccct ggatcactac ctctatgaag cggaggaagc caacttgggg cctggggtta     2040

gcatagtgga gcggcaatat atccaggacc ggattccctc ctggactgga gccggcttcg     2100

tccgagtgcc tgaaggggct tatttggagt ttttcattga caacatacca tattccatgg     2160

agtacgacat cctaattcgc tacgagccac agctacccga ccactgggaa aaagctgtca     2220

tcacagtgca gcgacctgga aggattccaa ccagcagccg atgtggtaat accatccccg     2280

atgatgacaa ccaggtggtg tcattatcac caggctcaag atatgtcgtc cttcctcggc     2340

cggtgtgctt tgagaaggga acaaactaca cggtgaggtt ggagctgcct cagtacacct     2400

cctctgatag cgacgtggag agcccctaca cgctgatcga ttctcttgtt ctcatgccat     2460

actgtaaatc actggacatc ttcaccgtgg gaggttcagg agatggggtg gtcaccaaca     2520

gtgcctggga aacctttcag agataccgat gtctagagaa cagcagaagc gttgtgaaaa     2580

caccgatgac agatgtttgc agaaacatca tctttagcat ttctgccctg ttacaccaga     2640

caggcctggc ttgtgaatgc gaccctcagg gttcgttaag ttccgtgtgt gatcccaacg     2700

gaggccagtg ccagtgccgg cccaacgtgg ttggaagaac ctgcaacaga tgtgcacctg     2760

gaacttttgg ctttggcccc agtggatgca aaccttgtga gtgccatctg caaggatctg     2820

tcaatgcctt ctgcaatccc gtcactggcc agtgccactg tttccaggga gtgtatgctc     2880

ggcagtgtga tcggtgctta cctgggcact ggggctttcc aagttgccag ccctgccagt     2940

gcaatggcca cgccgatgac tgcgacccag tgactgggga gtgcttgaac tgccaggact     3000

acaccatggg tcataactgt gaaaggtgct tggctggtta ctatggcgac cccatcattg     3060

ggtcaggaga tcactgccgc ccttgccctt gcccagatgg tcccgacagt ggacgccagt     3120

ttgccaggag ctgctaccaa gatcctgtta ctttacagct tgcctgtgtt tgtgatcctg     3180

gatacattgg ttccagatgt gacgactgtg cctcaggata ctttggcaat ccatcagaag     3240

ttggggggtc gtgtcagcct tgccagtgtc acaacaacat tgacacgaca gacccagaag     3300

cctgtgacaa ggagactggg aggtgtctca agtgcctgta ccacacggaa ggggaacact     3360

gtcagttctg ccggtttgga tactatggtg atgccctcca gcaggactgt cgaaagtgtg     3420

tctgtaatta cctgggcacc gtgcaagagc actgtaacgg ctctgactgc cagtgcgaca     3480

aagccactgg tcagtgcttg tgtcttccta atgtgatcgg gcagaactgt gaccgctgtg     3540

cgcccaatac ctggcagctg gccagtggca ctggctgtga cccatgcaac tgcaatgctg     3600

ctcattcctt cgggccatct tgcaatgagt tcacggggca gtgccagtgc atgcctgggt     3660

ttggaggccg cacctgcagc gagtgccagg aactcttctg gggagacccc gacgtggagt     3720

gccgagcctg tgactgtgac cccaggggca ttgagacgcc acagtgtgac cagtccacgg     3780

gccagtgtgt ctgcgttgag ggtgttgagg gtccacgctg tgacaagtgc acgcgagggt     3840

actcgggggt cttccctgac tgcacaccct gccaccagtg ctttgctctc tgggatgtga     3900

tcattgccga gctgaccaac aggacacaca gattcctgga gaaagccaag gccttgaaga     3960

tcagtggtgt gatcgggcct taccgtgaga ctgtggactc ggtggagagg aaagtcagcg     4020

agataaaaga catcctggcg cagagccccg cagcagagcc actgaaaaac attgggaatc     4080

tctttgagga agcagagaaa ctgattaaag atgttacaga aatgatggct caagtagaag     4140

tgaaattatc tgacacaact tcccaaagca acagcacagc caaagaactg gattctctac     4200

agacagaagc cgaaagccta gacaacactg tgaaagaact tgctgaacaa ctggaattta     4260

tcaaaaactc agatattcgg ggtgccttgg atagcattac caagtatttc cagatgtctc     4320

ttgaggcaga ggagagggtg aatgcctcca ccacagaacc caacagcact gtggagcagt     4380

cagccctcat gagagacaga gtagaagacg tgatgatgga gcgagaatcc cagttcaagg     4440

aaaaacaaga ggagcaggct cgcctccttg atgaactggc aggcaagcta caaagcctag     4500

acctttcagc cgctgccgaa atgacctgtg gaacaccccc aggggcctcc tgttccgaga     4560

ctgaatgtgg cgggccaaac tgcagaactg acgaaggaga gaggaagtgt ggggggcctg     4620

gctgtggtgg tctggttact gttgcacaca acgcctggca gaaagccatg gacttggacc     4680

aagatgtcct gagtgccctg gctgaagtgg aacagctctc caagatggtc tctgaagcaa     4740

aactgagggc agatgaggca aaacaaagtg ctgaagacat tctgttgaag acaaatgcta     4800

ccaaagaaaa aatggacaag agcaatgagg agctgagaaa tctaatcaag caaatcagaa     4860

actttttgac ccaggatagt gctgatttgg acagcattga agcagttgct aatgaagtat     4920

tgaaaatgga gatgcctagc accccacagc agttacagaa cttgacagaa gatatacgtg     4980

aacgagttga aagcctttct caagtagagg ttattcttca gcatagtgct gctgacattg     5040

ccagagctga gatgttgtta gaagaagcta aaagagcaag caaaagtgca acagatgtta     5100

aagtcactgc agatatggta aaggaagctc tggaagaagc agaaaaggcc caggtcgcag     5160

cagagaaggc aattaaacaa gcagatgaag acattcaagg aacccagaac ctgttaactt     5220

cgattgagtc tgaaacagca gcttctgagg aaaccttgtt caacgcgtcc cagcgcatca     5280

gcgagttaga gaggaatgtg gaagaactta agcggaaagc tgcccaaaac tccggggagg     5340

cagaatatat tgaaaaagta gtatatactg tgaagcaaag tgcagaagat gttaagaaga     5400

ctttagatgg tgaacttgat gaaaagtata aaaaagtaga aaatttaatt gccaaaaaaa     5460

ctgaagagtc agctgatgcc agaaggaaag ccgaaatgct acaaaatgaa gcaaaaactc     5520

ttttagctca agcaaatagc aagctgcaac tgctcaaaga tttagaaaga aaatatgaag     5580

acaatcaaag atacttagaa gataaagctc aagaattagc aagactggaa ggagaagtcc     5640

gttcactcct aaaggatata agccagaaag ttgctgtgta tagcacatgc ttgtaacaga     5700

ggagaataaa aaatggctga ggtgaacaag gtaaaacaac tacattttaa aaactgactt     5760

aatgctcttc aaaataaaac atcacctatt taatgttttt aatcacattt tgtatggagt     5820

taaataaagt acagtgcttt tgtataaaaa aaaaaaaaaa aaaaaa                    5866


<210>  2364
<211>  3995
<212>  DNA
<213>  homo sapiens

<400>  2364
tggatatatg tcttggagag aggctgtgtg cattagctac aaatagtaac attttcaaaa       60

tcaacatgta ttgtgcttat cctgtccctg gaatgggcag caattctttg atgtattact      120

acaatgggaa aacggtatat gcaccatccc caaattcaga tgatttcaac cgtgaatctc      180

ctagttatcc atctcctaag ccaccaacca gtatgttcgc tagcactttc tttatgcaag      240

atgggaccca caattcttct gacctttgga gttcatcaaa tgggatgagc cagcctggtt      300

ttggtggaat tctggggacc tccacttccc acatgtctca atccagtagt tatggcaacc      360

ttcattcaca tgaccgcttg agttatcctc cacactcagt ttcaccaaca gacataaaca      420

cgagtcttcc accaatgtcc agctttcatc gcggcagtac cagcagttca ccttacgttg      480

ctgcctcaca cactcctccc atcaatggat cagacagcat tctaggaacc agagggaatg      540

ctgctggaag ctcacagaca ggtgatgcac ttggaaaggc tttggcatct atttattctc      600

ctgaccatac cagcagtagt tttccgtcaa atccatcaac accagttgga tcaccttcac      660

ctctcacagg taccagtcag tggccaagac ctggagggca agcaccttca tccccaagct      720

atgaaaactc actccactcc ctgcagtctc gaatggagga tcgtttagac agactggatg      780

atgcaatcca tgtgctgcgg aaccatgctg tgggaccttc caccagtttg cctgctggtc      840

acagtgatat acatagttta ttgggaccat cccataatgc accaattgga agcctcaatt      900

caaactatgg aggatcaagc cttgttgcaa gcagtcgatc agcttcaatg gttggaactc      960

atcgggaaga ctctgtcagt ctcaatggca atcattcagt cctgtctagt acagtcacta     1020

cttcaagcac agacctgaac cataaaacac aagaaaatta tagaggtggc ttgcaaagtc     1080

agtctggaac tgttgttaca acagaaatca agactgaaaa caaagaaaag gatgaaaacc     1140

ttcatgaacc tccttcatca gatgacatga agtcagatga tgaatcctcc caaaaagata     1200

tcaaggtttc atctagaggc agaacaagca gtactaatga agatgaggat ttgaaccctg     1260

aacagaagat agaaagggag aaggagaggc ggatggctaa caatgccaga gaacgcttac     1320

gcgtgcggga tattaatgaa gcattcaaag agcttggccg aatgtgtcag cttcacttga     1380

agagtgaaaa accccaaaca aaactcctta ttcttcatca agccgtggca gtcatcctta     1440

gtctagaaca gcaagtcaga gagaggaacc ttaaccccaa agcagcctgc cttaagagaa     1500

gggaagaaga aaaagtttct gccgtatcgg cagagccgcc aaccacactg ccaggaaccc     1560

atcctgggct tagtgaaact accaacccta tgggtcatat gtaaacatca gccagttcca     1620

gagttatcag taggctagat agaaggtgac ctctcctcat aaggacttgg acaactcaga     1680

ttatctgaag acacaaacct gacaggaggg agaagaaaaa acaaaacact tgaaccaaga     1740

aactcaaatg taatcctacg atcaaagcaa ctggtcaaca cttccatcag aagtgaagat     1800

aggaagctca tcagatagaa catcagccca tgagatgttt gcaacaaatc ttttgttgca     1860

agcagtgtgt cgcttctgca caatcagaga ctgtctcgat ctctccactc accgtggaag     1920

ttgccttgtg cctaaactga attgacaaat gcattgtaac tacaaatttt atttattgtt     1980

atgaaactgt aaggtctaca tataaaggga aaaagttaat gtggaaagct gatctacact     2040

cagctgatgc cagcatacat taaagcggtt cacgtgcaga gaacaaagca gtgacaacca     2100

ttggccctta gcattcccgg catacctatt agtgtcttaa aaaggaaggg aaaagtcttt     2160

tgttgccctc tcctatcctc ttgccatatg aatagcgttt tccatgaaat aggaaaatat     2220

tacttggtat agcatttctc ttgctctcat tttttgattt atttttattt tctctttgtg     2280

ggtgttatat ttgatctcta aatctgaaca gtttatggtc acagtccagc ctcctccgtg     2340

cagccctgtg tgctttgcac atttacctta cagtggtaag cagagaccat ctgtgaccat     2400

agcctagcta gcattttaaa aggggaaatt ttgttctcta ggttttcccc caaataaaca     2460

ttgctttatt tctaataata accaagactt ttcaagcttc tagatctcat aggaaagctt     2520

gtaatagcaa aattgtaaat tacaagggaa gaatctactt tttagaaatc gctttgtttt     2580

ccaagcagta agtactacat acagtacttg taaagtgtta gctgtaagta agcacaaaat     2640

acatttaaaa tacaaagacg attttttcag gctgtgatta tggtgaacat aacaaaaccc     2700

agtagtcacc aaggcaggta gtgtgataaa tgaacacacc actctgaggc taattaccta     2760

atggaataca agagcaatgg tcacccgtat ttccttatcc tagcctttat ttctctgtca     2820

tttggatggc tggtcaatgg ggaagaattg agtgggtgat ttaatcaact gcaaaccatc     2880

tgcccctgtc ccaaaatgat gagccagatt agcattaaac cagtacttgt cagtccatct     2940

taatactgtt cattaaggca ctctctgtct ctaatcctta ggagttgttt taaaagacat     3000

aatcactttg aacttccatg aaacctgtct tccaccacaa caaccctggg agagaaaaac     3060

atgctaaagg aggtatcttg gcttaataat tccttatagc caatatcaac agtggcaatc     3120

agcacacaga ggaaaggacc caaatcacta tgtagcttaa agatttctgt taatttgaaa     3180

gaacaaaaac aagacagaac ttctggtact ctaatcagga tgattcctaa caagtcagtc     3240

atttgtgaac ttagtggact ttttggttac tttaatttgc atatattctc cagttacatc     3300

ggactctatc tgtggccttg ttcttcattt cagtgttaat cagctaaaca gaagttgttg     3360

cttatgatgt gtgagtgaac atatgccact gcctggcctt tttttcttca gagcttgttg     3420

tctttttcgc tatattagac tttgcagtat gcccagaagc tttccttcat aaaatagaaa     3480

gaaaaaaaca tttggcttat ttttcactgt agctagtctt ttatacaata atcttgtaag     3540

aaaatttctt gaattctaaa tattactctt tctagatttt tgaaatcaaa aagttttcag     3600

taaaaagttt cttactttat tttattatat taggtagtaa aaaatgtagg gttatttacc     3660

ataacctgtt cattaatatc agaaatttac aatagcattt taagaccata gtaggattct     3720

agcataccgt gtagtaccta tggagtattg taagagctaa ttgttggaga tgaattgctt     3780

ctcatcttgt tctccagttt ccattgttgg tttattgcag atttgtatcc tgtgtcaaat     3840

tcaaggtatt attgataaac cttttcaacc agcagcaaga agttcaaatt tttttctgtc     3900

actgtaacag aaaacacaat atgtatataa catttatgta gcaataaatg tgccatcttt     3960

tttttaacac agtaaaaaaa aaaaaaaaaa aaaaa                                3995


<210>  2365
<211>  3973
<212>  DNA
<213>  homo sapiens

<400>  2365
agcgggacag acgagcggga ggggcagcgt gcggggagct gggggcgggg cgcggccgca       60

gctccgtttc cggtggctcg tcgcgctcgc tcactccagc tgcagccact ctcgcccgtg      120

gctgcttcct ccatcctggt attttttgga gcttccatcc tggttcttcc aaagtgcccg      180

gacccaaaac aggaaagtgt tgcggagata ggaacatggg agagaaacaa tctgggtaac      240

atgaaagtga tgctggttgc taagggaagg caacttgatt ctgtgggaag ggctgtagct      300

gatccatccg ttgtctagat ttgagtatga gcacagtgga agaggattct gacacagtaa      360

cagtagaaac tgtgaactct gtgactttga ctcaggacac agaagggaat ctcattcttc      420

actgccctca gaatgaagcg gatgaaatag actcagaaga tagtattgaa cctccacata      480

aaaggctttg tttgtcctct gaggatgatc agagtattga tgattctact ccttgcatat      540

cagttgttgc acttccactt tcagaaaatg atcagagctt tgaagtgacc atgactgcaa      600

ccacagaagt agcagatgat gaggttactg aggggactgt gacacagata cagattttgc      660

agaatgagca actagatgaa atatctccct tgggtaacga ggaagtttca gcagttagcc      720

aagcatggtt tacaactaaa gaagataagg attctctgac taataaagga cataaatgga      780

agcaggggat gtggtccaag gaagaaattg atattttgat gaacaatatt gaacgctatc      840

ttaaggcacg cggaataaaa gatgctacag aaatcatctt tgagatgtca aaagacgaaa      900

gaaaagattt ctacaggact atagcatggg gtctgaaccg gcctttgttt gcagtttata      960

gaagagtgct tcgcatgtat gatgacagaa accatgtggg aaaatataca cctgaagaaa     1020

ttgagaagct caaggaacaa ctgtggaccc caaaaaaagg ccacactttc aaactttggc     1080

tctcaaagta ttgctgccca caacttccaa accagtcaaa tgggaagaag aagaatgaag     1140

aataaatgat gaaattaaaa gggagaaaac aattgaacca aatgctgatt ggcagactct     1200

tgttttaggc tccggataaa gcatggcaat gactgggcaa caataggggc ggcgctagga     1260

agaagtgcat cttctgtcaa agatcggtgc cgactgatga aggatacttg caacacaggg     1320

aagtggacag aagaagaaga aaagagactt gcagaagtgg ttcatgagtt gacaagcact     1380

gagccaggtg acatagtcac acagggtgtg tcttgggcag ctgtggctga acgagtcggt     1440

acccgctcag aaaagcaatg tcgttctaaa tggctcaact acctgaattg gaaacagagt     1500

gggggtactg aatggaccaa ggaagatgaa atcaatctca tcctcaggat agcagaactt     1560

gatgtagctg atgaaaatga cattaactgg gatctgttag ctgagggatg gagtagtgtc     1620

cgttcaccac aatggctacg aagtaaatgg tggaccatca aaaggcaaat tgcaaaccat     1680

aaggatgttt cgttccctgt cttaataaaa ggtcttaaac agttacatga gaaccaaaaa     1740

aacaacccaa cgcttttgga gaataaatca ggatctggag ttccaaacag taataccaat     1800

tccagtgtgc agcatgttca gataagagtt gcccgcttgg aagataatac agccatctct     1860

tctagcccca tggcagcatt gcagattcca gtccagatca cccatgtttc ttcagcagac     1920

tctcctgcta ccgttgactc agaaacaata acactaaaca gtggaacact acagacattt     1980

gagattcttc cctctttcca tctacagccc actggcactc caggcaccta cctacttcaa     2040

acaagctcaa gccaaggcct tcccctaact ctgactgcta gtcccacagt aaccctgaca     2100

gctgctgctc ctgcttctcc tgaacagatt attgttcatg ctttatcccc agaacatttg     2160

ttgaacacaa gtgataatgt tacagtgcag tgtcacacac caagagtcat cattcagact     2220

gttgccacag aggacatcac ttcttccata tcccaagcag aactgacagt cgatagtgat     2280

attcagtcat ctgattttcc tgagcctcca gacgccctag aagcagacac tttcccagat     2340

gaaattcatc accctaagat gactgtggag ccatcattta atgatgctca tgtatccaaa     2400

ttcagtgacc aaaatagcac agaactgatg aatagtgtta tggtcagaac agaagaagaa     2460

atctctgaca ccgaccttaa acaagaggaa tcaccctctg atttagccag tgcttatgtt     2520

actgagggtt tagagtctcc cactatagaa gaacaagttg atcaaacaat tgatgatgaa     2580

acaatactta tcgttccttc accacatggc tttatccagg catctgatgt tatagatact     2640

gaatctgtct tgcctttgac aacactaaca gatcccatac tccaacatca tcaggaagaa     2700

tcaaatatca ttggatcatc cttgggcagt cctgtttcag aagattcaaa ggatgtcgaa     2760

gatttggtaa actgtcatta gaataattct tagaaatagg cagttcaagc aaagaaggca     2820

cactgttaat tacaacctct tcaaagaaat aggagcaacc cccaagaggc ttaatttacc     2880

aatttaaata gccacagtcc ttaagccaca cacattgttg ctgctatgac tttttacctc     2940

ctttaaacac atcatctgag gttgagtttt atgacagtat gtagttgagt ggaggctggg     3000

agttttaagc ataaatccct gtttagtgtt acatgggaat aaggaatttc attcacttca     3060

gccactaaga aaagtttaga atcacgaaag cttaactgct gtggtttaaa gtacagtttc     3120

tctaaagatc agacatggca ctgtctcctc tcaagcctgg ttgtagttca gatgagtctt     3180

ttcaacatgg tcttcaacat ggtctagagc ttaccagtga tcttctgatc ttcaagaaga     3240

ctaagtttga gacttgacca gcatacaagt atagagacct aggaggtggt cttgtggtgg     3300

tacatttggt taacccattg ctggcagtgg gagctgattt aggcagggta aacaggaaag     3360

cattaaaagt taaaattcac tacaggtttt ttgttacttt taaagggaat atggataagc     3420

atagtaacaa aacccaccag aatctaagca gttttcaccc cctcagaaac cactgtcatt     3480

agtttacaaa gttagcactt tgaagtaaaa ctaaatgagg aaggaagtaa tgttacctat     3540

ccttgatacc atgaccattt attagatgtt ttgctatata aattaccgag agaatagttt     3600

gtcatccact tagtgtgtta gctggtgggg tacaatataa cctctcatct caggctattt     3660

taaaaaaaca atatttgctt ctataacaaa aggaaacaaa tctaagaatc attcctgtac     3720

tacagaaggg ttaaggcaaa ggtagccttt tgggcttttt aatgaatatg acccctatag     3780

aaaagtcaag aaaaaaaaac ccttgtataa attattttat ttattattgt aattagatct     3840

tcacaaagtt gtcttttcac tgtgttttgt caacgtgaaa ttaaattgta gttataagca     3900

aaagttggtt gcctagggaa caattgtata ttcagtttaa cagaaataaa agaatatttg     3960

tcttaagatg caa                                                        3973


<210>  2366
<211>  7046
<212>  DNA
<213>  homo sapiens

<400>  2366
actacctttt ctcttcggtt ggctgtagtt taaattctaa ggtctcctca agaaatgaca       60

ttttcacatt tcttaggcat ctgtggtgcc agaggagcaa acccatcgca cacgccaggt      120

ctgccatggg gccctgggcg gtggggattt tggatgtaac gtgtctaggc cgagcccgcg      180

ccgtgaaagg cctaccctgc cgaaagcccg ggcggcgggc gcccacaagt cagggctcgg      240

tgcggcgccg cagccagctc tgcccgcgag ccgagtccgg gctgctgagg gggagccgcg      300

ctgggggcgg cggcgtcggg gcgggggcgg gagccgggcg gcagctccag cgcccgtggg      360

ggaggagcgg cagcggcggc ggctggagct gctgtggcga ccgacgcgag gcggtggcag      420

aggagaccca cccctgtcca catggacagt cgcaaaggcc tccgctgatg cattcacgcc      480

tgggcggggt gggcggacgg ccgtagcggc ggcggctgca gaacgagcta ggggcctggg      540

ggcgcctgac ggtcgcagag acctcgccgc tccggcgcgg cgggtgcggc cattttacgg      600

cctgggacga agggaggcgt gtttgtgtgc tcgctttcat tctcctttct tgggaaccca      660

cggctggggg aagtttctca ggcagcctgg gtgggcggtg gatggggagt cgtgggccga      720

gaggaaccgg gcccgggaag cgccgtcgtc gtcgtcgccg gtcgcgttcc cccggagagg      780

cctgagaagc tcgggccgcg ggcctcgctg cccgccagcc cgcggacagg cccgggcgcg      840

cctggcctgc ctttgtatag gcccgtctga acgtgggagc gcagcccgcc tgacggctga      900

gcccgaggcc cgcaaccctg cggcgtctac cctcctccgg cgcggcccct catcccggcg      960

agcacggcgg cggtgtgggc catggattaa gaaggaggcg gcgtgggagg aggaagatgg     1020

cggccggcaa gagcggcggt agcgcagggg agattacttt tctggaagct ttggctagat     1080

cagagtctaa gagagatgga ggttttaaaa ataattggag ctttgatcat gaagaagaaa     1140

gtgaaggaga tacagataaa gatgggacaa atctgctcag tgtggatgaa gatgaggatt     1200

ctgaaacctc aaaaggaaaa aagttaaatc gtcgatctga aattgttgct aatagctctg     1260

gtgaattcat cttgaagaca tatgtaagac gaaacaagtc tgaaagtttt aaaactttga     1320

aaggcaaccc aattggactt aacatgttga gcaacaataa gaaattgagt gaaaatacgc     1380

aaaatacgtc attatgttct ggaactgtag ttcatggtag acgttttcat catgctcatg     1440

cacagatacc agtagtaaaa acagcagccc aaagcagtct ggaccgaaaa gaaaggaaag     1500

aatacccacc tcatgtccaa aaagttgaaa ttaatcctgt aaggttaagt cggctccaag     1560

gtgttgaacg tataatgaag aaaacagaag agtccgaatc acaagtggag cctgaaatta     1620

agaggaaagt acaacagaaa cgacactgta gtacctatca gcctactcct cctctatctc     1680

ctgcttcaaa aaaatgttta acccatttag aggatttgca aagaaattgc agacaagcta     1740

ttactttgaa tgagtctact ggaccattat taagaacgtc aattcatcag aattctggag     1800

gacagaagtc acaaaacaca ggattaacaa ccaagaagtt ttatggcaac aatgtggaaa     1860

aggttccaat tgatattatt gtgaattgtg atgacagtaa acacacttat ttacagacta     1920

atggaaaagt cattttacct ggggcaaaaa tacccaaaat cacaaacttg aaagaaagga     1980

aaacaagttt gtcagaccta aatgatccaa tcattttgtc cagtgatgat gatgatgaca     2040

acgacagaac taacagaaga gaaagcatat ctcctcagcc tgctgattca gcatgttctt     2100

cccctgcacc atccactgga aaagtagaag cagcgctaaa tgaaaatact tgcagagcag     2160

agcgtgaact acgaagcatt ccagaagact cagagttaaa tacagttaca ttgccaagaa     2220

aagcaagaat gaaagaccag tttggcaatt ctattatcaa cacacctctg aaacgtcgta     2280

aagtgttttc tcaagaacct ccagatgctt tagctttaag ctgccaaagt tcctttgaca     2340

gtgtcatttt aaactgtcga agtatacgag taggaacact cttccggctg ttaatagagc     2400

ctgtaatttt ttgtttagat tttatcaaga tacagctaga cgaaccagac catgatcctg     2460

tagagattat attaaatacc tctgatctaa ctaaatgtga atggtgtaat gtccgaaaat     2520

tacctgtagt gtttcttcaa gcaattccag cagtttatca aaagctgagc atccaactgc     2580

aaatgaataa ggaggataaa gtttggaatg attgtaaagg agtaaataaa ttaacaaatt     2640

tagaagaaca atatataatt ttaatttttc aaaatggcct tgatcctccg gcaaatatgg     2700

tatttgaaag tatcattaat gaaattggta taaagaataa catctccaat ttttttgcga     2760

aaattccctt tgaagaagct aatggcagac ttgttgcctg tacaagaacc tatgaagaga     2820

gcatcaaagg aagttgtggg caaaaggaaa acaaaattaa aactgtatca tttgaatcta     2880

aaatacaact tagaagcaaa caagaatttc agttttttga tgaagaagaa gaaactggag     2940

aaaaccacac catcttcatt ggcccagtag aaaagttgat agtatatcca ccacctccag     3000

ctaagggagg catctctgtt accaatgagg acctgcactg tctaaatgaa ggagaatttt     3060

taaatgatgt tattatagac ttttatttga aatacttggt gcttgaaaaa ctgaagaagg     3120

aagacgctga ccgaattcat atattcagtt cttttttcta taaacgcctt aatcagagag     3180

agaggagaaa tcatgaaaca actaatctgt caatacagca aaaacggcat gggagagtaa     3240

aaacatggac ccggcacgta gatatttttg agaaggattt tatttttgta ccccttaatg     3300

aagctgcaca ctggtttttg gctgttgttt gtttccccgg tttggaaaaa ccaaagtatg     3360

aacctaatcc tcattaccat gaaaatgctg tcatacagaa atgttcaact gtagaggaca     3420

gttgtatttc ttcttcagcc agtgaaatgg agagttgttc acaaaactct tctgccaagc     3480

ctgtaattaa gaagatgcta aacaaaaaac attgcatagc tgtaattgat tccaatcctg     3540

ggcaggaaga aagtgaccct cgttataaga gaaacatatg cagtgtaaaa tacagtgtga     3600

aaaaaataaa tcatactgcg agtgaaaatg aagaattcaa taaaggagaa tctacatccc     3660

agaaagttgc tgataggact aaaagtgaga atggcctaca gaatgaaagt ttaagttcca     3720

cacatcatac agatggctta agcaaaatca gactaaacta tagcgatgaa tcacctgaag     3780

ctggtaaaat gcttgaagat gaactcgtcg acttctcaga agatcaggat aaccaggatg     3840

atagcagtga cgatggattc ctcgctgatg acaactgcag ttcagaaata ggacagtggc     3900

atttaaagcc tactatctgt aaacaacctt gtatcctact tatggactca ctccgaggcc     3960

cttctcggtc aaatgttgtc aaaattttaa gagagtattt agaagtggaa tgggaagtta     4020

aaaaaggaag caaaagaagt ttttccaaag atgttatgaa gggctctaat ccaaaagtac     4080

cacagcaaaa caacttcagt gactgtggtg tatatgtatt gcagtatgta gagagctttt     4140

ttgagaatcc aattctcagt tttgaactac ctatgaattt ggcaaactgg tttcctccac     4200

caagaatgag aacaaaaaga gaagaaatcc gaaacataat tctgaagcta caggaagatc     4260

agagcaaaga gaaaagaaag cataaggaca cttactcaac agaagcacct ttaggcgaag     4320

gaacagaaca atatgtcaat agtatctcag attgaccatt tctgttactt gtcatttcta     4380

ctttcagaaa ctaaatgact ttcaaatttg ggtatagaca ataaagaact gaagtgctca     4440

ctactcagtg atttggaaat tttgatgctt gtataaatgt cagataatta atttccaaag     4500

gcgtatgtat taagtaaaag tctgtaaata tgttaatgag gccaattttt ccagcattta     4560

taattatttt tttcacttgt taggaagctt ttgttatgta ttttctgtta atagtaccta     4620

aaattgcaac ttctaaacac aaataaaaag aaaatattta taggaggaaa tgattaattt     4680

gatattcttt agtgaacttg tttaattcct cagtgggtgt gacatatttc atgggaatat     4740

tcaaatatct atggtaatat tttgaccctt tatatttgtt ctaaaataag tcaaaatgtg     4800

aaaataatat taaatctaag atattttgaa ctaagcatct ttatatgctt gtgtaacagg     4860

aacaaagtaa cagcctttca attcatatac tgccttgtgt tcagtgaacc caagaaatgt     4920

aataaatatt tgtaatttta cacaaatatt taagaggaaa gagtattaag agcaattcaa     4980

aaaaagtaac cttatactac taaaaaaaaa attcttgcat atattatcat caaatgcatt     5040

tttgaagaca tcaaagactc aggttaaaac tattttggta agtgcagctt gaatttcaaa     5100

tatcccgtgt tacctttctc tattacagct taaagtatgc tacaatctgt gtcatatagt     5160

taattgataa gcatttttaa tctgtgtaaa cacaggaatt taaataggaa tttactattt     5220

ttttataaag cttttgctat tttttcattg ctcattttgt tcttattatt ttgataaagt     5280

atcagacttt ttgcttgagt tcttcagtgt aaattatttt ttacatgtaa aagtactgta     5340

ttcaaccagt tgcataatac agcaaaaatc tttgaattcc cctttaaaat aactaaaatt     5400

tgatggtttc catgacagat ttatagcaca tatagggatc ttgcatgtat ctgcagaaac     5460

ttcattattt ttcaaatgaa atggtgtata cttctttcaa atgaactttg agacttgaaa     5520

catattttag tcattttttg ttaaatattg aatttttaaa tacacatata tcaaaaatag     5580

ttgagaataa aaagaaagcc taatcatcag caattatttt atttttaatt tggccatctc     5640

tgacattgca gtcaatatct tagggtattt tcttgaattt aataaagtcc catgggtggg     5700

ttcagggtga atgggagtat taacaacaac caaaaaatat ctattgagac acagtagagt     5760

ctcagtaaga gaaatattaa aatgtaagaa aggtcaccat tagtgatatc aactgtagtt     5820

tgttactttg aactatattt ctgattaact ctttatagta ataacttaga gctgttagct     5880

cagatatctt aattagctca tatgaaaaac aagtttaatt ttattattta ctgaacatgg     5940

caaaatgctt ttcaatctat aataaaactg ggataaaaaa ttgaagttgt tttttttaaa     6000

acctaatagc aataagcaaa attggcatac ataatttttt taatgaacta tattttgtca     6060

gaatctgaag gtactgaaaa actattctaa aatgcctact tgtttttgca ttaatttgta     6120

atgcttacat tttgcaccct tagataatgt ttgataagat aaaaatataa tttatccctt     6180

gtaccaactc aagtcaatca gattttaaca tgaaaaatat agattaatgt atgtcagctt     6240

tctagaggta gaatactcag ctatttgatg gcatttttcc caccccatgt gaaattttat     6300

ttttggaagt tatgctagtg acattgcaat atatattgaa atcttcggag gctgccaggt     6360

tgagcttcaa aactagactt gagaatcttt cgtgtatatg cacattcact tgataattgt     6420

gtattctatg tagtttaaag tgggatcaag ccttttaaaa tgtgttatta gtacttagaa     6480

gttgtaaaac agaacttata gaggtttgtt actagacact gaaactgcat gacaagtatc     6540

tggtgtctta actaattaga tagatctgtt gtattggttt tcttgttgga tagaataaca     6600

gttaatcatt tttagaagag ttttagatta cttgccataa aatttgtatg tctcagctct     6660

tgttggttta ggagcagaag tggtgtttag tcccttcccg ttaatgttgc tgtgctactt     6720

cagacagctg aaaacttaat ggtattattt caagttcaca taaccctaaa aaaggttttc     6780

tttgtgtagt aacttgtgct taaactttta gtcaattaaa tgtaggaggt tttatttgaa     6840

aacataaaat gattctctaa attacatctt gttttaagcc accaaaatga atgcagtaat     6900

ttttctttaa aaaaatgatc tctgaaaact gtgagacaat gtaaaaagaa taagttttaa     6960

ttcccccaaa atcaaaaatt gtacttaaaa tctcagacaa ttcactgaac aggaataata     7020

aagaacatat tttaatatat aatatg                                          7046


<210>  2367
<211>  2063
<212>  DNA
<213>  homo sapiens

<400>  2367
gctgggagtc ctggtgccgc cggctgcact tctgtgtgtc tttcaggaag ccacagggca       60

gggggcgtct gtgcagagaa gcgggggagt gagtagcagg caggcccagc ttgtgtacca      120

gcccagtgac atatatagaa acataaatca ggctagagcc ggcgcgcccg ggcgcgcacc      180

tgtgtatgga cccgcaggca tgtctgtaca ctgggtgggc acctgtcttg tgagtggctc      240

cgggtgtggc tgctcctcgg actttcagtt tatgtaagat ttatctctag gggcctacct      300

tcccccatct ccagagggga acataagaag tttaacggag ctgggactga gcagattaag      360

ggagtggagc ggaggctggg ccggagagag tggggactgt gagtgctagt gggtaaggat      420

ccatctgttt gccccgtccc ccagccagaa aggcattttg gaaagactgg cgtggcaagc      480

gtcgccctga aacgtccaca gagcccaaga agtgatgatc actgagtgag tggcactggg      540

ctgagactgg ccagtttgtt aacaacaggg atgctagcag ttaggaaggc caggaggaaa      600

ctcaggatgg ggaccatctg ctcccccaac cccagcggga caaagacatc atcggaggtc      660

tgcaatgccg actggatggc ctcgctcccc cctcacctcc acaacctccc cctttccaat      720

ctggcaatcc caggctcaca tgattcattc agctactggg tggatgaaaa gtccccagtg      780

gggcctgacc aaacccaagc tatcaaacgc ctcgccagga tctccttggt gaagaagcta      840

atgaagaagt ggtctgtgac tcagaacctg acatttcgag aacagctgga agctgggatc      900

cgctactttg acctgcgtgt gtcttccaaa ccaggggatg ccgaccagga gatctacttc      960

atccatgggc tttttggcat caaggtctgg gatgggctga tggaaattga ctcgtttctt     1020

acacagcacc cccaggagat tatcttcctg gatttcaacc acttctatgc catggatgag     1080

acccatcaca aatgcctggt tctgcggatc caggaggcct ttggaaacaa gctgtgccca     1140

gcctgcagtg tggaaagttt gacgctgcga actctgtggg agaagaactg ccaggttctt     1200

attttctacc actgtccctt ctacaagcag taccccttcc tgtggccagg aaagaagatt     1260

ccagcgccct gggcaaacac cacaagtgtg cgcaaactaa tcctcttctt ggagaccact     1320

ctgagtgagc gggcctcacg gggctccttc catgtctccc aagcgatcct cacccccaga     1380

gtgaagacca ttgcccgggg cttggttggg ggcctcaaga acacgctggt tcataggctg     1440

gcactgatcc cagtttatcc tttgagattc agcagaagat cctgatggag gaggaggata     1500

ccaagagaga ggtgcccaag gaagatggag ttggtgatgt gcaacatttc ggtgagaact     1560

ttattgtcag aggttttcag tacatattta caagttctta ctccatcata catattggga     1620

atgagctggc attttcaagc atatacccag gagtccagca atcattgggg aagagagcct     1680

gaggctggca atccttgccc agaactttgg tcacctgctt gttcacaggc caccatatct     1740

tacttcactg aagtcatatg ctgaggtttt atttagtcca gatgctgaag gatgggaaga     1800

cccaagcagc tggtgtggag gtctttccca gtgactcatc agtcattcag aaatcaaagc     1860

ctgcacaaga aagggtggga tgggatgtat agagaaagac accaagcctt tagactccag     1920

cagagtagct gatattgaca tatctgagga gggaggaggc tccaatacga ctactcccaa     1980

ttcacagggt ttgtggttct ggatgaaatc tttgcaaagg gtttccctgg cactcaaaca     2040

gaataaatag gcttataaag tgt                                             2063


<210>  2368
<211>  11347
<212>  DNA
<213>  homo sapiens

<400>  2368
gcggggagcc ggcggttatc tgggcggcgg agcgctcaca atgtggcagg agacagaaaa       60

gataagatgc tcccaagtcc cttgcagctc tcttcagaag aaaaatcact agtgctctgc      120

tcttgccata ataccaaacc tttttgactc atgctttggt gctgcaacac tggaagaatt      180

gcacacagtt tccaggaata tctttttttc atttgagtga ttctttgtgg atgagaaaag      240

atttgagtct taataattac cttgttttaa agctatttct ttatagtctg aactgtttaa      300

taaattgggc cacttaccaa tgagccacac agccagttct tgtcaggagc tggttgaaaa      360

ctgtgctgtg catgtagcag gaatggcaca agaagatagc cgtcgtggtc aagtgccatc      420

ttccttttat catggtgcca accaagaact tgacctgtcc accaaagtgt acaaaaggga      480

atcaggaagt ccttattctg tgttagtgga caccaagatg agcaaaccgc atctccatga      540

aacagaagaa cagccatatt tcagggagac aagagcagtg tctgacgtgc atgctgttaa      600

ggaagaccgg gagaattctg atgacacaga ggaggaagag gaagaagtct cttacaaaag      660

ggagcagatc atagtggagg taaaccttaa taatcaaaca ttaaatgtat ctaaagggga      720

aaagggtgtc tcttctcagt ccaaagagac tcctgttctt aagacaagca gtgaggagga      780

agaggaagag agtgaggaag aggccacaga tgacagcaat gactatggag agaatgaaaa      840

gcagaagaaa aaggagaaga tagtagagaa agtcagcgtt acacaaagga gaaccaggag      900

agctgcctct gttgccgcag ctaccacttc ccctactccc agaactacaa gaggtcgtag      960

gaagagtgta gagccaccta agcgtaagaa gcgggccaca aaggagccca aagcaccagt     1020

ccagaaagct aagtgtgaag agaaagagac tctgacctgt gagaagtgcc ccagggtatt     1080

taacactcgc tggtacctgg agaagcacat gaacgttact cataggcgca tgcagatttg     1140

tgataaatgt ggcaagaagt ttgtcctgga aagtgagctg tcccttcacc agcaaacaga     1200

ctgtgaaaaa aacattcagt gtgtttcctg taacaaatcg ttcaagaaac tctggtccct     1260

tcatgaacat atcaagatcg tccatggata tgcagaaaag aaattttcct gtgaaatttg     1320

tgagaagaaa ttctatacca tggctcatgt gcggaaacac atggttgcac acacaaaaga     1380

catgccattt acatgcgaaa cctgtggaaa atcattcaaa cgcagtatgt cactcaaggt     1440

gcactccttg cagcattctg gagagaagcc ctttagatgc gagaactgtg acgaaaggtt     1500

tcagtacaag taccagctac gctcccacat gagcattcat attgggcaca aacagttcat     1560

gtgccagtgg tgtggcaagg atttcaacat gaagcagtac ttcgacgaac acatgaaaac     1620

acacactgga gagaaaccct ttatctgtga aatctgtggc aaaagcttca ccagccgccc     1680

caacatgaag agacaccgca gaactcacac aggcgagaag ccctatccat gtgatgtgtg     1740

tggccagcgg ttccgcttct cgaacatgct taaggcccac aaggagaagt gctttcgggt     1800

gaccagcccc gtgaatgtgc cacctgctgt ccagatccca cttacaactt ccccagccac     1860

cccagttcct tctgtggtga acacagccac aaccccaacc cctccaatca atatgaatcc     1920

tgtaagcact cttccccctc ggcccatccc ccaccccttc tcacacctgc acatccaccc     1980

acaccctcac cacccacacc accttcccat ccctccagtc cctcacctcc cgccacctcc     2040

agctctcttt aagagtgagc ctttaaatca tagaggccag agtgaggaca actttctgcg     2100

gcacctggca gagaagaaca gttcagcaca gcatcattaa catccgtctc cttagtgtgt     2160

tctccaggag acacgtcccc atgtgtgagc gtgcacagag ggagtcggtg agcatttcct     2220

tagttctcag actctcctcc gcctctacca agagcttcgc cagtgtcact gaatcaacag     2280

atccaaggga atgaacaaga agactacctt gagctcacag agggactgtc atctaaacca     2340

ggggaaccac tgaactaaag cccaatttgc ttgcattttc tgatgacttt tataagtttc     2400

aaatactcag acttgtggaa ttttataatt tcatatcagc tgatgaggta tgcttgcttt     2460

tatatcccag acttctcctc aaagagggga taggcctggt ttcctttgta ctaatcggga     2520

aggctgtgag attaatccag agcattaatt gtatcactgt gtatggtaag gaattctttt     2580

cagcttttgg tgccagctac agagttgagc tggccatgtt tcacagtata tcaagcatta     2640

tagagaaaga cagaaatttt cttctttgtg tagctctcct aacgcactct ttattttact     2700

acagaaatta ttttagagtt tttgtataga cttctttggt agtctgtttc taaaatgaaa     2760

tgtatttcaa taagcagtgt aattttttca gtgtagctga acctatgttg taaaatagaa     2820

aaaaattttt ataatcatca aaatgtgatt cttaaagatg catataactt ctataattca     2880

aagctattct tacatccgta caactcaaaa ggtgcttcag agactagatg tatctgagag     2940

ggtctccaga ccaggttact gcaaaaatga ggttttgctt tcaggatttg gcgtaaatac     3000

ttggtagttt tgacatctct gcttaacact caagagaggc tccctaatgt gctcctgtcc     3060

tccatgttct gcttggcttc gttagtgcat tacatgaaat gatttgcagg ggatggggcc     3120

ttttccaggg aagtcaccta aagcttgcat gttttgaaaa tttgaataag gctgtttgct     3180

gacaggagga ggaagtagtg gagatcattt catctcagtc acgtctgttt ctcacttccc     3240

ttaggaattg tgttgatgtt taacttttat gggatgacaa attgaaatcg ctcattttga     3300

ggttgcttta tttttctaga attgttataa gaagctaaaa tagtaaactt aaaatcacaa     3360

acatgacatt gctgatagtg gctgagaaat tcagatgaga agacaaattg gttatgaatt     3420

ttgaaatatc tattatatgt aaaatgtgga tatgttcaca accttgagct attttaacac     3480

agtttaaata tagtgaggga aaactcctaa gttttactgc cctgtcctct gcaaattatg     3540

taataccagc attcttaggc gataaagaga gcagcacctc tagtaccttt aggcagatta     3600

ctttttcaag tttggggaac ttcaaaagac cataatcaac caggagctta ttataggaaa     3660

ggctgaacag aagggctagt gtattgatta cacttaacag atcatattta tccagactca     3720

gtatagctta aaattttgta tttctttatc tgagagaact gagttcccag gctaaatcac     3780

ttacctccca ccccctctcc aatttttttt ttaagagaca aggtcttgct atgttgccca     3840

ggctagagtg cagtggctat tcacaggtgc agttatagca cactacagcc tccaactctt     3900

gggttcaagc aaccctgcct cagctaacca agtagctggg actacaggtg catgctacca     3960

tgcccagtcc attttttaat cttgaaattt cttcattttt ctttcttcgg tttcttaaaa     4020

tctttgcctg aatcagaacg ctggctttta tttatttttt tatttttaat attaaatgtg     4080

cagatatgct tcgagcactt ttctaactaa tgagctctgt ggtaagaaaa aatgaactct     4140

ttcaattgag attaagtcca tatttttcaa acatcacgtt ctctattggc tttttggttt     4200

agtgtttcta aattttctcc ttctgatttt gcctgtctta tataatgagc ataggaaaat     4260

tttggaatga ggcagaaaag tatatcaaga catacttcct ggttttggat gtaagtttta     4320

aagaatggta tttttaatat ttgtacacat tctttgagca cccaggtacc caagccaata     4380

aggaaagtta attccttgca tatgactgtt atatctttag tggttgtctc cctctccctc     4440

cacagtctcc ttggcattcc atgacaagtt tgtcaaccta cacttttata tagacatatc     4500

attatttcat ggtcaagcct gtagtattaa aatgattttt ttaaaagatg taaactgtgc     4560

ttagttaatt ggttatattt tgttctgttt tttttttttt tttttttttt tttttgaggc     4620

agagtcttgt tctgttgcct gggctggagt gcagtggcgt gatcttggct cactgcaacc     4680

cccgcccccc gggttcaagt gattctcctg cctcagcctc ccgagtagct ggaattacag     4740

gcatgcgcca gcacgcccgg ctaagttttg tatttttggc agagatgggg tttcaccata     4800

ttggccaggc tggtctcaaa ctcctgacct tgtgatccgc ccacctcagc ctccgaaagt     4860

gctgggatta caggcgtgag ccaccacgtc caactgcctt attttgttct gaataaattt     4920

acagtattgg gcagcaattc tggattctag acttgagacc acagaatcaa ccatttcatg     4980

aggttgtact gtaattatac actggaatat tcaggtagtc atctttgatt tttcattcaa     5040

gtaaatatag ccataagaaa atatctgcta tacaggaaaa ccagtattaa gcaaatacca     5100

ccatccttaa cagaaacaaa aatatatata tatattattt ttaaaaatta gcattgtcat     5160

acagtacaat tcttagtgaa gtgtattgtg gaacaattta gaaacttcct ttttttcccc     5220

tagattaagg atactttcct tgacttgaga cttgtggtct tcaggaaaac tactcagaat     5280

ataatgactc ctcatcagta tcatattgta tataaataat gaaatgcatt aagaatattc     5340

acaacattga acccaggagg cggagcttgc agtgagccga gattgcgcca ctgcgctcca     5400

gcctgggcaa cagagcgaga ctccatctca aaaaaaaaaa aaaaaagaat attcacaaca     5460

ttaatgcttc tgaatagaag aactgcagga ttaagcctta aacatatatg tgcaacacgt     5520

ttaacatgct taagactcaa actcagggtt gaaaatttgg ttggggtcct ctttgtaaga     5580

taaaagttgc attatgtggt atgttctctt ccatatatgc tacagcaccc catgaattct     5640

tcaaaacttt ttacctactt gttatctgtt tatgaaaaaa agaattatgg agaagtttga     5700

gttctcagcc cttatctgta catgtctgtt aaagacaaca aaggctgcat ttaagcatta     5760

tatagataac aaattgaggc tgtctctcgt tacttagttt tactgtcttc aaaggcttgt     5820

atcattgcta gggttaagac ttatttgagg atgagttggc attgtatttt ttgtgtgtgt     5880

gggttggttt gtatttgttt cgtttttatt tttctatttt ctctcataga tttatcagta     5940

aaatataaac tcttccttag ccttaataaa ggctgctgct ttctcaaatt gagtcagata     6000

ggctcattcg gagttagatt tttaaatttg aatgaagaaa agacaacaat ttaaaggcat     6060

gtggcttcat ttccacatat atttgtgact ggattcttat ttttagcaag aggggagatc     6120

gccacaaaaa aaactttagt tcaaagaaga ctgtgcaaat cagttacctg tactttcata     6180

gtctaccatt tacattaact gttctagatt aatgactaag catggccatt accataatta     6240

catcattttt ttaaaaccac atttgttcga agtatccttt tctagtggtt agaactgtcc     6300

ctataatttg attgtccctc atatactaac cgaaagcaaa atgctctgat gagatgctta     6360

taaactatga attttttaat tcttgaaatt tttttcagtt tttatgattg ttgaatagat     6420

atgtatgttt agttccatta ttatttcact ggaagtttta aattttgaga agatgaagca     6480

gagatagaaa tccattgcag atatatgtat atttacccca tcttgcaggt ttcagttagt     6540

aaaacacaga atgataggtc ggttttaatg ttttaaaaaa aaactaaaaa actaaagtta     6600

gagaaacctt tctgtttgag ctactgtata gaaaagacaa cttttattgc attgctggtc     6660

cacatgataa atatttcaat gctgttctag actgtatgag aagtacttaa tgaaaaaagg     6720

gatacattac atttaagaat tgtatcagct aattactgtt ttaaaaaaat caactcattt     6780

ggaattcttc ggactataaa attgagcaag taaagtttgg gttttaattt tcctttgcct     6840

gaaccaagat aggaaattac ttaagagttt tttttttttt tttttttttt tttttttagg     6900

aatgaaaggt cataagccat tagaaatagt ggcattatta tgcaataaca acaccctagc     6960

taacctgctt ttgtcatctg tagcacttac aataaagaat gatgaccttc caaccctgga     7020

cactacctcg ataaagcaaa ccagagatcc tctctacact ttctatggaa gccataaaag     7080

ttgccatcaa tatatccact ttcatagttc tatactttta tactttctag acttttttat     7140

agactttatg atcagatctt tttgtctcag aggataggtt ttgcaagatt caaaggaaaa     7200

tcaaactcct tggttgttcc agctttgaag cttttgcttc agtaaatttg tttaaagaac     7260

cagatcacat accatttatc aaattcttta cttaagtcag aatactttgc agacatacat     7320

atttggaaaa caaactgttt cttgttcact agatagaatc tgtattgtag taagaaacta     7380

cttacaaggt ggctttcttt ctgctttgtt actctatgta ttactcaata atatatgtat     7440

ggtcacaggt tcctggagtt gttttatttc tttatgacag acacatgagt atgcacctct     7500

ctctaatcct ctgatgtcac tgcagcttca gtctctctca ctctgttttt gagtgccttc     7560

aaaatgccag catcctggaa cattcttttc ctgatctaaa tcctacctct gactatttca     7620

ttatccatga atattggaat tcacccatat tccaatgggc ttaactctac aaactagcta     7680

aaaccttgga caagaatttt gaccgtattt ctgttttgtt cctccatgtc atttttaggt     7740

tatattttta acttttattt atatcttatt tcttcacata tttcgtctct ctgttgaaag     7800

attttatcct tatttgactc ttcacttttt ttactttcac cagaaatttg acgttccttt     7860

aaaattaaag gtcattgaat gtcttttgaa cacctttttc tcaactgaag tcttcctgaa     7920

tgcctcccct ttctgatgaa aggatcctga gtgctgctgt tgctctgccc tgttcccatg     7980

tgcccactcc cttccgtaca cattttgcaa gactatactc tttattttag tcaaattaat     8040

ttaaaattgc tccctgggtt tctgctctct catggccctg tccctcaaaa acttctgttt     8100

actttttcta gctgttttca tctaatttgt ttaaaatgta tgatggatcc ataatatatg     8160

aaggatgtaa tgaaaaggag gttgcagtgt tttatataat atgatcgagc acctccgtga     8220

tgaaacattt agcaattggc tagtccttca cagccagagt ggaagtttgt gctgtggaca     8280

ggtcttttta ctcccttcca gttctcctcc aaaactggag aaaaaggaaa aaaaaaaaga     8340

actctttcaa atgaggagat ttgattgcat ttttttaggt gaatgaaagc ttggagttga     8400

gcatttgggc cttagtcagc atttttcctt tctgacttaa aatctcatgt ccttttcctt     8460

aaagttaata gtactcaggt ttttaagact aataaccaca caaggtgggt atctaagaag     8520

gcagctgtta atacattctc catctttcct gtctggcaac aggaaagata ttattggtga     8580

gatagtgcaa aattgtgaga attggttatg tttgatgatg aataaattca agatttttga     8640

aggcttcact gctatttggg atgggaaggt gagtttacaa aatgaaaaag gtagattttt     8700

atgttacaga aatcagtaac gggtttcttg ttgtgttaat tacctttcac ttgatttgcc     8760

atgatgtttc ttcctcatta ttgatctaga agtttgcctc ttggatagta actagtaact     8820

tagtatctac tttaaaattt gtggcttttc tcttcagggt cccaggccat aaaacaacgg     8880

agagctgtac ttgcttgtca cttggaggaa ccacatcctt gagacagcct gctgtcttgt     8940

atgtcttcag taggaaactt ctgacacaca cattcaaggg agttcctgcc cctgagaagt     9000

gttcccatag ctttccagtc gcaggttact ttcacactac gtcagcttct ctggtgagat     9060

cagggatgtt acatattact tgaaaatgat ttcataggaa gtgaggatgg ggcaagaaag     9120

gaggtagaag ctgaattttg cttaacttca gaaggaaatc tgatacttgc cttggctagt     9180

tctgatcaac taaagagcct gtgtctgtac tggatgtgcc aaagagtcaa gttgtttctg     9240

gaatatccag ctcctctgaa tgaacacagc ttcctcccta cctgtctttt atgggtgaaa     9300

agggaccgtc tgatgagcat gatagacatc ctgtacagga ctcaagactg tttcattgca     9360

tttgaaagtt ggtgggaagt attttattct gctagagctc ctaaccctcc tagaaatatc     9420

ttttcatgct ctattaattc aattcattag tttaaaaaga aacagtgtga cataattttg     9480

gtgtttactt cttaagttgt ctccccaagg gcatatatgt agcctctgaa aatgggatga     9540

tttcttctca atcttccata aatttgaata tgcattttat tcatttcttg acatgggctg     9600

tgtgactgtt ttccatcagc agttctggct ttgtccacaa gggagcaata aagtacgtta     9660

gctttattct caaccttcta aagaaagatc ccacttttaa atctcttctg gaatagcctc     9720

ttagctcaaa gcttattcat gtattttgat tatttaagaa attttccctt attacaaagt     9780

ccagtcgtcg ttcatccctc atgatgccaa gcaatgattg atgtgtgggt gtggagtcct     9840

tgtgggtcag gcatcttaat taattagact ttttacatat tgatgatccc cagattgaaa     9900

gccaggacct tcccataggg gcgcctttgt gtgctaaagg cagagcaggc aggcttctcc     9960

actcctatct cctccgcagg ccaccaccat cacatctata ggaggaacaa gagcactggg    10020

ggaactctgg agtatgagta aggaaatgct tctcaccttc tctgctccaa agagatatct    10080

gttacatcag ggaacaagtc ctctaggtca ggcacttcct cctgaccagt gcaacgggca    10140

ctccaggtta gaaactgtgt gtgctccctc tctgtcagtt acttgtctaa gggctcctat    10200

ccgtggtcat cagctctctg gccatgagtt ctgtttgtgc ttattgcagc agcatcttca    10260

caacaaacag gtcagtaatc aacctgggaa gggaaaagac gacagtaaat attaccccct    10320

gtagagccgg gaggcattta cacctggaat ggccttctta actgatttct gcctggccac    10380

ctcaccccca gccaagtctg aacctgagca ataccaggca cagagaggtg tctacttgta    10440

actccaacac ttgacaaaaa acaaaactga agctgtgatt ggtttaggca gcaagtggcc    10500

aggtgcaact tgtttgtttt tatttttgtt ttccccaaca gtactgagat cacttgcact    10560

tttcctcatt tcttaagaaa atccagtttg cttgccatga cttgtttagc gttaggttta    10620

caaagcttgt tgttgaatgt tgaatatttg tccaaaggag tttgacaaaa tagaagctgc    10680

ttggtccctg ttctgcctgc taggtcataa ggatgaaggc catgtggctg gggtacttat    10740

gtcaagtcca gaatggggca gtgtccctct cctacctctc tgcggagacg caattgaagg    10800

tcaagtagac tcagtgtagg gcaggcagct gtcatgctgc aaagaagttt agaggagtct    10860

ttgggttggg gaggtgacag gtaggtagga caggatctct taagatggga aagatactgg    10920

ggagaggagg gctgcttggc cccagggaac tgcagtgagg tggaactgag ctccgctcct    10980

gaatctccaa aggagcccat gctgcccggc ttccctgagt cattttttcc agcatcctgt    11040

cagatccctc aatgtactga tttccccctt gtgttaacta taccgatatt atttttttag    11100

caattgaaat gcactttttt atttcaactc aatcatgatt ttaagtataa aaaatttata    11160

gattgttaaa actacttttt tgtgtatttt taaccactca atgtagcatt gtatatttta    11220

ttcttgtgag actctggtac aggtgtgccg cctaatgatt tttctgagat gctgggcctt    11280

tggatgtgta cggtaaccaa cttaatgcta atgttcaaag taaaaaaaaa aaaaaaaagc    11340

agccata                                                              11347


<210>  2369
<211>  4322
<212>  DNA
<213>  homo sapiens

<400>  2369
aaagataagg cttgaacttt gcacttgcaa atgtcactgc atacgttttt gcactagttt       60

tttttttttt ttttctgcga ttcttttaca actaatttct tttaacaatt tgagcgcagg      120

gaagagaatg tttagggtta tgagatgcat taagtttaga acgagttgat gctcggcttt      180

tgaatgcact tgtcttcttt atttttaaag caatataaag cactcgagtg tgtgttttca      240

gcccctcctg gaatgggaaa ataagaatct ccctggatgg gagtcctctg gggcagggag      300

tgaaagcccc ggaggcagaa agggacggag aacaggggct tgcccagagc atggatagga      360

aaggagctgg ggttctccgg ggctcagcgc gcactgagaa cctgtgcccg gggctgcagc      420

tgcggacgat aaaggcgctg tctggctcat gaaggccacc tggatcaggc ttctgaaaag      480

agccaaggga ggaaggctga agaattctga tatctgtggt tcggcagact cctacactag      540

ccgtccatcc gattccgatg tatctctgga ggaggaccgg gaggcagtgc gcagagaagc      600

ggagcggcag gcccaggcac agttggaaaa agcaaagaca aagcccgttg catttgcggt      660

tcggacaaat gtcagctaca gtgcggccca tgaagatgat gttccagtgc ctggcatggc      720

catctcattc gaagcaaaag attttctgca tgttaaggaa aaatttaaca atgactggtg      780

gatagggcga ttggtaaaag aaggctgtga aatcggattc attccaagcc cagtcaaact      840

agaaaacatg aggctgcagc atgaacagag agccaagcaa gggaaattct actccagtaa      900

atcaggagga aattcatcat ccagtttggg tgacatagta cctagttcca gaaaatcaac      960

acctccatca tctgctatag acatagatgc tactggctta gatgcagaag aaaatgatat     1020

tccagcaaac caccgctccc ctaaacccag tgcaaacagt gtaacgtcac cccactccaa     1080

agagaaaaga atgcccttct ttaagaagac agagcacact cctccgtatg atgtggtacc     1140

ttccatgcga ccagtggtcc tagtgggccc ttctctgaag ggctacgagg tcacagatat     1200

gatgcaaaaa gcgctgtttg attttttaaa acacagattt gaagggcgga tatccatcac     1260

aagggtcacc gctgacatct cgcttgccaa acgctcggta ttaaacaatc ccagtaagca     1320

cgcaataata gaaagatcca acacaaggtc aagcttagcg gaagttcaga gtgaaatcga     1380

aaggattttt gaacttgcaa gaacattgca gttggtggtc cttgacgcgg atacaattaa     1440

tcatccagct caactcagta aaacctcctt ggcccctatt atagtatatg taaagatttc     1500

ttctcctaag gttttacaaa ggttaataaa atctcgaggg aaatctcaag ctaaacacct     1560

caacgtccag atggtagcag ctgataaact ggctcagtgt cctccagagc tgttcgatgt     1620

gatcttggat gagaaccagc ttgaggatgc ctgtgagcac cttgccgact atctggaggc     1680

ctactggaag gccacccatc ctcccagcag tagcctcccc aaccctctcc ttagccgtac     1740

attagccact tcaagtctgc ctcttagccc caccctagcc tctaattcac agggttctca     1800

aggtgatcag aggactgatc gctccgctcc tatccgttct gcttcccaag ctgaagaaga     1860

acctagtgtg gaaccagtca agaaatccca gcaccgctct tcctcctcag ccccacacca     1920

caaccatcgc agtgggacaa gtcgcggcct ctccaggcaa gagacatttg actcggaaac     1980

ccaggagagt cgagactctg cctacgtaga gccaaaggaa gattattccc atgaccacgt     2040

ggaccactat gcctcacacc gtgaccacaa ccacagagac gagacccacg ggagcagtga     2100

ccacagacac agggagtccc ggcaccgttc ccgggacgtg gatcgagagc aggaccacaa     2160

cgagtgcaac aagcagcgca gccgtcataa atccaaggat cgctactgtg aaaaggatgg     2220

agaagtgata tcaaaaaaac ggaatgaggc tggggagtgg aacagggatg tttacatccg     2280

ccaatgagtt ttgcccgttt gtgttttttt tttttttttt ttgaagtctt gtataactaa     2340

cagcatcccc aaaacaaagt ctttggggtc tacactgcaa tcatatgtga tctgtcttgt     2400

aatattttgt attattgctg ttgcttgaat agcaatagca tggatagagt attgagatac     2460

tttttctttt gtaagtgcta cataaattgg cctggtatgg ctgcagtcct ccggttgcat     2520

actggactct tcaaaaactg ttttgggtag ctgccacttg aacaaaatct gttgccaccc     2580

aggtgatgtt agtgttttaa gaaatgtagt tgatgtatcc aacaagccag aatcagcaca     2640

gataaaaagt ggaatttctt gtttctccag atttttaata cgttaatacg caggcatctg     2700

atttgcatat tcattcatgg accactgttt cttgcttgta cctctggctg actaaatttg     2760

gggacagatt cagtcttgcc ttacacaaag gggatcataa agttagaatc tattttctat     2820

gtactagtac tgtgtactgt atagacagtt tgtaaatgtt atttctgcaa acaaacacct     2880

tcttattata tatataatat atatatatat cagtttgatc acactatttt agagtcttaa     2940

tgccaagtca gcagatttgc tttatgaatt acagggacta gaaatgccca cattcaggaa     3000

atttgtaata acattgtcta gacacctatc ctcattctag tagaaagtgt gtacatactg     3060

taaatatgtg tgattgcttg acttgaaaag gtttgaattc tgaatgttat accatccttg     3120

taagtaagtt tgtaatttcc accataaatt atggtaaata taaaactcca gaggttgttc     3180

tactccatac agttcacact gattgtgaca cattcttagt agctagtgtc tgttctagtc     3240

actgcactgg agtctacgag ccggaactcg ctatatgcac gtgtgtgtgt ccgtatgtaa     3300

gaaagtgtgc accgagtgac tgaatggttg agatgaattg gaatgctgaa gactaacgaa     3360

gaaactagag actgatatcg agcattctgc ccacctcgct ctgtatttaa ttaattgtgc     3420

tatatgttgc tttaacaacc cattgagcag tcagggaatg tgagtaagct tgctgccaaa     3480

ggtaactagg aaagcattca tctgctgcct ccttgttttt gctcctagag agtgaaaata     3540

caggcaattt tactgtgagt gtttcactgg aaatgtacaa tctttgtgtg ttagagtatt     3600

tgttttagta agaaatgttt acacagcttg tggaattatt tcgtgggaaa ataaattttt     3660

ataacttctc ccacttcaat ttctaacctt gcctattgtt cctgttgttt gtttacctcc     3720

cagttaccta ccattcctcc ccaccaccga ctccagcagg ttcactgtct gtcagaaccc     3780

agaagtgctt cttataacca aagtttctgt tcttcagaag aaatcagggc aaaatggggt     3840

gacttgaagt gaataaaatg ttaagaatat tatcctacat aagacatgta cacagaaggg     3900

gaaccttgaa gacattatct ccatgcctca attacactgc tgtaagaagc ttacaatgtc     3960

atcatgttta aggctaagac cttttccgtg tctcaagtgt atattttgtc cagttataac     4020

tggatggtaa gacagtatta agagtgcaag tacctggcac ttgaagtttg tcccaggaaa     4080

atgcctgtgt ataattacct aacttcagat ctgcacatta acttatttaa caaaataaat     4140

cagccgggcg cagtggctca tgcctgtaat cccagcaatt tgggaggctg aggagggtgg     4200

atcacctgag gtcaggagtt caagaccagc ctggccaacg tggcgaaacc ccgtctctac     4260

taaaaagata aaaaattagc caggtgtggt ggtgcacacc tgtaatccca gctacttggg     4320

ag                                                                    4322


<210>  2370
<211>  5635
<212>  DNA
<213>  homo sapiens

<400>  2370
aaagccttcc caagccccca aggcatgctg ggagatgcag tccctttttc taaagactgg       60

ggcggccgtg aggtcatcgg tggtcgccgg gagccgccag cacgtggcgg cgaggaaggg      120

gcggtgtgct cctgttgtct gcacctgaga gggggcagga gctctcggcg cttgcgcctc      180

ccgccgcggt gccctcccga catgccggag gaggcgggct tcccgccggc caagagattc      240

cggccaggct ctggacctcc gagccgcgct gggtccttcc ctcccgggag gcaagtggtg      300

atgctgctga ctgcgggcag cggcggcaga ggaggaggag gaggccggag gcagcagccg      360

cccctggccc agccctcggc cagtccctac cctgaagctg tggagctgca gcgccggagt      420

ctgcccatct tccaagcgcg ggggcaactg ttggcccagc tccgaaacct ggacaacgcg      480

gtcctcatcg gggaaactgg ctctgggaag acaactcaga tccctcagta cctgtatgaa      540

ggagggatca gccgccaggg catcattgct gtgacccagc ctcgtcgagt agctgccatc      600

tctcttgcta ctagagtctc agatgagaag agaactgaac ttgggaagct ggttggctat      660

acagtgcgct ttgatgatgt cacctcagaa gacaccagga tcaagtttct gacagatggc      720

atgcttctgc gtgaagcaat ttcagactct ttgcttcgga aatacagctg tgtcattttg      780

gatgaagctc acgaacggac tatccacaca gatgtgctct ttggagtggt gaaagctgca      840

cagaagagga gaaaggaact cgggaaactt cctctgaaag tgattgtgat gtcagctacg      900

atggatgtgg acctgttctc tcagtatttc aatggcgccc ccgtcctcta cctagagggt      960

cggcagcatc cgatccaggt gttttacacc aaacagcctc agaatgatta cctgcacgcc     1020

gcgcttgtct ccgtcttcca gatccaccag gaagcccctt cttcacagga catcctggtg     1080

ttcctcactg ggcaggagga gatcgaagcc atgagcaaga cgtgccgaga cattgcaaag     1140

cacctcccag acggctgccc tgcgatgctg gtccttcctc tgtacgcctc cctgccctat     1200

gcacagcagc tccgagtctt ccaaggggcc ccaaagggct atcgcaaagt gatcatttca     1260

accaacatcg ctgaaacctc cataaccatt acaggaataa aatatgtagt tgacacgggc     1320

atggttaaag caaagaagta taaccctgac agtggtcttg aggtgttagc agtgcagcgg     1380

gtatcgaaga cgcaggcttg gcagcgcaca gggagggctg gcagagagga cagtggcatc     1440

tgctaccggc tctacacgga ggacgagttt gagaagtttg ataagatgac cgtgccagag     1500

atccagaggt gtaacctggc cagtgtgatg cttcagcttc tagcaatgaa agtcccaaat     1560

gtgctcacct ttgacttcat gtcgaagcca tctccagatc acattcaggc ggccattgcc     1620

caactggacc tgttaggtgc tcttgaacat aaggatgacc agcttaccct gactccaatg     1680

ggaagaaaga tggcagcatt tcctttagaa cccaaatttg ccaaaaccat cctcatgtcc     1740

cccaaattcc actgtacaga ggagatcctg accattgtct ccctgctgtc tgtggacagc     1800

gtcctccaca accctccttc ccggcgagag gaagtgcaag gggtccgcaa gaagttcata     1860

tccagcgagg gggatcacat gaccctgctc aatatctatc ggaccttcaa aaacctaggc     1920

ggaaataagg attggtgcaa agagaatttt gtcaacagca agaatatgac gctggtagca     1980

gaagtcagag cacagctgag ggacatctgc ttaaagatgt caatgccaat cgcatcatcc     2040

cgaggagacg tggagagtgt ccgccgctgc ctggctcaca gcctcttcat gagcaccgcc     2100

gagcttcagc cagatggcac ctatgccacc acggacaccc accagccagt ggccatccac     2160

ccgtcgtctg tcctcttcca ctgcaagccg gcctgcgtcg tgtacactga gctgctctac     2220

accaacaagt gctacatgcg ggacctctgc gtcatagatg cacagtggct gtacgaggct     2280

gcccctgagt actttaggag gaagctgaga accgccagaa actgagccgc cccaggatgc     2340

cgccagaatc actggtccct gggagcttgg actacagttg tccttacagc aggcttccag     2400

gttggcgctt agagaagcct tggaatcagc tgaaggtgcc tgacttccag gagcgtgaaa     2460

gcatctttgc tcaactcctg ggactgaacc atatagacat ggacatatca tttgtacctg     2520

gaaacctcaa aattatgctt ttggttctta ctgggtgact ttgacttaat ttaacacctg     2580

agcctcagtt ttctcatctg ccaaatggga gtaataataa taatccttat aaaattgggt     2640

tcataaagtt tagagaaaag gaatggaaag tacccagaac tatgcctgga gcacgcacga     2700

cacacgtaca gtgagttggg agccgttagg ctgaatgtta ctgcttgcca tatgatgtga     2760

agtacagcaa tatcccaagt tcttgtgact gagggagatt ttctggaagg gccacaggag     2820

gttgcggagc ttggatgttg cccttagttc ttgtttaatg tctctctgaa tgcagtttta     2880

aaatagaaaa caaaactgac ttctgtagaa gtttccagag ggaggtgctg ttatctcgta     2940

cctcctggga tggcgatccc tactgaacgc ttgtgtctca gggtggacca ctctgtgtct     3000

gtctccaagc agagaccagt aaaggagcct cctggtcctc agtgcgtgac cctgtcagtg     3060

ctttcaggag acatgtaagc ttcctgggtg aaggttgatt tgtaccttct gaatcctgtc     3120

acgtgtagac atgggaaact gacctatcag tgttttgtgt gtgtaggtga ctcccacata     3180

cacagttgcc atttttctct ctaactgggc accagtgaac atgcgggcat gaggagtgac     3240

tgtgtaccat ttcagctgtt tcttttcggg cagtcccctg gtcagagggg gtgggggtgg     3300

gggaggggag aggggtacct agaacccaga gaacattggc ttatgccaga taccacacca     3360

catctgggct tacattcttg tatctttttt ggtgtgtggg cggggggggt ggggggcagt     3420

tcagtgaagt ctagaagacc tgctggacaa attctaaaag agctagagct gtaacactta     3480

ttcttgcatc ttattaattt tctatgatat tttttccttc ttcgtaggga cttgggacaa     3540

tctggctttg ctgctttcta actgctaggc acctctctct aaccctcatt gtcagaggga     3600

attggaggat atccacagtc tgttcctgtt ctgatattct gagcagagaa aaggcactaa     3660

cggttcctct tagctattta attatcagaa gcaagtaatc tttccccaga taatattttg     3720

ccctagaaga agccgtgatt tagctctttt attgtgctta cttggtccaa atacatctgt     3780

ggggtgtttt gtcatttctt aatgaatgaa tcatagttat aaccaggggc caagctgccc     3840

aagaggctct tcagagatca tggatgctct ctttctggaa gctgtggcct gatggagcag     3900

ccccattcca gggtcccatc tgtccggagt tgtgtatgtc aagtccggct cagtctttat     3960

ttccaacact agccgtggtc ctgtgcagtc aagctctcag ctagtgttta gggctgtctg     4020

tcagaaatgg ttatacgtgg gcaaaagaag atctgacagc tcctatatac cttatcttac     4080

tgaattctta aactttgaac cagttcttcc acttactgac ttgttaccac tgctgacttt     4140

ctgaaaagtt ttccagtttt tgttttttgt tttttgtttt ccagtagggg attagaatgt     4200

ttagtcctac ttagtaagaa aaatattgta tttttaatca ttcatagtgc tggtaaaaaa     4260

aaaaaaaaaa aaaaaaaaat tggggggtgg ccgggcgcag tggctcacac ctgtaatccc     4320

agcactttgg gaggccaagg cgggcggatc acctcatgcc tgtaatccca gcattgggat     4380

gggaggctga ggtgggtgga ttgcttgaga agttcaagac cagcctggcc aacatggcaa     4440

aaccccgtct ctactaaaaa tagaaaactt agctgggcat ggtggcacac gcctgtaatc     4500

ccagctaccg gggaggctga ggcacaagaa ttgcttgaac ttgggaggca gagtttgtag     4560

tgagccaaga tcacgccact gcattccagc ctggccgaca gtgtgagacg gtctcagaaa     4620

aaaaaagaaa gaaagaaaga aaaagaaaaa acttggggta atttatgtcc agcttaagta     4680

cctgaacagt ttccggaaat gtatattttt tttctgagag gcaaaggatg taaacagctt     4740

ctaagtagct ttaatgtttc tgtacagaaa taagtttatc cctgtaacat tgtggtagag     4800

ttttaataca gtatttagtt ttttattggg cttttttaaa aagttaactt ttaacatagc     4860

tgctcaggga ttaaatcaga ttggaaaacc cattctgact ccacatactg ctacaaagaa     4920

atacatcgtt gtttatattg agctgcagga gatagtacac tttaaactta agaaagttaa     4980

atgtttcaca ataacattgc aatataatct tcagctactc tctttccatt ggtaaaatct     5040

ctgatggtgt gataactctt tgccaaccta cgaaacccat atctggaaga atcaccagct     5100

cccgtgagca gcttcatgta aatagatgca ctccaagcag attgcatgcc tcaggtgttt     5160

gtcttctagt aatcatggag tgtgcaacac ccagagtaac actacaaggg gcaggactgc     5220

aaacagcagg tcctggctaa aaacccttaa tgctgcattg ctgccagttg taaagagatg     5280

cctgaatgga ggcaagttct gccctgtggg tgaaactgat gatgtactgt actgtcatat     5340

ataaatccac taaatccagc taccaggaac tgcctggaac tgtggccatg catttttttt     5400

tttctttaaa gaccagtgtg atagtaggcc atgcatctga gatacgatat tccttggtaa     5460

ctagagggag aaaaaaaaat caagtaggtt caggcttatg ttgtattttg agagtctggt     5520

tttatttgaa cagaaataac tctacagaaa gctcttgtaa ataatgctca aatttgcacc     5580

cgacgatcaa atccattaaa aatgaatctt gtatatgaaa aaaaaaaaaa aaaaa          5635


<210>  2371
<211>  4604
<212>  DNA
<213>  homo sapiens

<400>  2371
ggcgcgttcc ttcctcttcc tctctcctct ccggccccgc cttcccttcc ctccgcccac       60

ctccctgaag cggagccgcc gtcgccacca gcgccgtcat gtcggccccc gccgggtcct      120

ctcacccggc cgccagcgcc cggatcccgc ccaagttcgg cggagcggcc gtctcaggag      180

ccgcagcgcc cgcgggcccg ggtgcgggcc cggcgccgca ccagcagaac ggtccagccc      240

agaatcaaat gcaggttcca tctggatatg gattgcatca tcaaaactat attgctccct      300

caggacatta ctctcaagga cctgggaaaa tgacctcatt gccattggat acccagtgtg      360

gtgattacta ctctgctctc tatacagtac caacacaaaa tgtgactcct aacacagtga      420

accagcaacc aggagcacag cagttgtaca gcaggggtcc tcctgcccct catattgtgg      480

gatccactct aggatctttc caaggtgctg catcgtcagc atcccatttg catacgagtg      540

cctcccaacc atactcctct tttgtgaatc actacaatag tccagccatg tactctgcca      600

gctcttctgt tgcgtctcag ggatttccct ctacttgtgg tcattatgct atgtcaactg      660

tttctaatgc cgcgtatcct agtgtttcat atccctctct gcctgctggt gatacatatg      720

ggcaaatgtt tacctcacag aatgctccga ctgttaggcc agttaaagat aattcattct      780

ctggtcaaaa tacagctatc agccatccat cgccacttcc acctctacca tcacaacagc      840

accaccagca gcaaagtctt tcaggataca gtactctaac gtggtcatct ccaggccttc      900

catcgactca agacaatctc atccgaaacc acacaggatc cctggctgta gcgaacaaca      960

acccaaccat tactgttgca gattctttat cctgtcctgt tatgcaaaat gttcagcctc     1020

ccaagtccag cccagtggta tccactgttt tatcaggatc ctcaggatcc tcatcaacaa     1080

gaacacctcc cactgcaaat cacccagttg agcctgtgac ctcagttaca cagccatcag     1140

agctattaca acaaaaaggt gttgacagct cttctaccac aagcagtgct tctccaatgc     1200

ccaacagtta tgatgccctg gaaggaggca gttacccaga tatgctttct tcatcagcaa     1260

gcagtcctgc tcctgatccc gcccctgaac ctgatcctgc ttctgctcca gctccagctt     1320

cagctccagc tcctgtcgtc cctcagcctt caaaaatggc taagcctttt ggctatggct     1380

atccaacact tcagcctggt tatcagaatg ctacagcacc acttatttct ggagtacagc     1440

ccagtaaccc ggtatattct ggattccagc agtatcctca acagtatcct ggtgtgaacc     1500

agctatcctc cagtatagga ggattgagtc ttcagagttc tccacaacca gaaagcctga     1560

gacctgtaaa ccttactcag gagaggaata ttttacctat gactcctgtt tgggctcctg     1620

tacctaactt gaatgcagac ctcaaaaaat taaactgtag cccagattca tttcggtgta     1680

ctttgacaaa tattccacag acacaggctt tactgaataa agctaagctt cctttaggat     1740

tgttgttaca tcccttcaga gacctaacgc aattaccagt gataacatca aataccattg     1800

tgaggtgccg atcctgtcga acgtatatta acccctttgt atccttcatt gatcaacgta     1860

gatggaaatg caatttgtgc tatagagtaa acgatgttcc tgaagaattt atgtataacc     1920

cccttacccg atcttatgga gagcctcata aacgaccaga agttcagaat tcaactgtgg     1980

agttcattgc ttcttcagat tacatgctgc gtcctcctca acctgcagtt tacttgtttg     2040

ttttagatgt gtctcataat gcagtggaag ctggatattt gacaattttg tgccagtcac     2100

tcctagaaaa tctagacaag cttcctggag attcacgaac aagaatagga ttcatgacct     2160

ttgatagcac tattcatttc tacaatttac aagaaggatt atcacagcct caaatgttga     2220

ttgtgtctga tatagatgat gtttttctac ctacaccgga tagtttactt gtgaatctat     2280

atgaaagtaa agagcttata aaagacttac tgaatgcatt accaaacatg ttcaccaata     2340

caagagaaac acacagtgcc cttggtcctg cacttcaggc tgcctttaaa ttaatgtctc     2400

caacaggtgg ccgtgtgtct gtatttcaga cacagttacc ttccttgggt gcaggacttc     2460

tgcaatccag agaagatcct aatcagagat caagtacaaa ggtggtacaa catcttggcc     2520

ctgcaactga tttttataag aaacttgcat tagattgctc gggacagcaa actgcagtgg     2580

atttgttcct tttaagttca cagtattctg atcttgcttc tctagcttgc atgtccaagt     2640

attctgcagg gtgcatctat tattatccat cattccacta tactcacaat ccttcacaag     2700

cagaaaagtt acaaaaagac ctaaaacggt atctcacaag aaaaattggg tttgaagctg     2760

ttatgagaat aaggtgtact aaaggtcttt caatgcacac ttttcacggt aacttctttg     2820

tccgttctac tgatttgtta tcccttgcca acatcaatcc tgatgctgga tttgcggtgc     2880

agttgtcaat tgaagaaagt ttaacagata cttccttagt atgttttcaa acagccctat     2940

tatatacatc aagcaaaggt gagcggagaa ttagagtaca tacactttgt ttgccagtgg     3000

taagttcact agcagatgta tatgcgggag tggatgtaca agctgccatc tgccttctgg     3060

caaacatggc tgtggatcgg tccgtttcat caagtctgtc agatgcaaga gatgccttag     3120

tgaatgctgt agtggactca ttgtctgcat atggctcaac tgtctcaaat ttacagcact     3180

ctgcattgat ggcgcccagc tccctcaagt tgtttcctct ctatgttttg gcccttctca     3240

aacagaaagc atttagaacg ggtacaagca cacggctgga tgatcgtgta tatgccatgt     3300

gtcagataaa gtctcagcca cttgttcatc taatgaaaat gattcatccc aacttataca     3360

ggatagacag attgacagat gagggtgcag tacatgttaa tgacaggatt gtaccacagc     3420

cacctcttca aaaattgtct gcagagaagc tgacaagaga aggtgctttc cttatggact     3480

gtggctctgt tttttacatt tgggttggga aaggctgtga caataacttc atagaggatg     3540

tgcttggata tactaatttt gcatcaatac cacagaaaat gacacatctt ccagagctag     3600

atacactttc atcagaaaga gccagatcct tcataacttg gcttagagac agcagaccat     3660

taagtccaat ccttcacata gtaaaagatg agagtcctgc caaagcagaa ttttttcagc     3720

atttgattga agaccggaca gaggctgcat tttcttacta tgaatttttg cttcatgttc     3780

agcagcagat ttgtaagtga agtagaataa aattgaataa gaaaaagatc tataacctag     3840

gtaaagcata atctgtcaga gaagcgcgtg agaaatttga aatgaaggca tttgttaata     3900

caagatgcaa cgcacagcac tctgtctgag gctttggtaa aaagtaaagg ggaagaaaga     3960

acttgacaga tctttttcaa ctcaaattaa tggtaacgat gatgctgttt caccaagtat     4020

attttgaatt ggtttctaca catttccagt agtatggcag tacagtgctc tgttcattgc     4080

aagctggcaa atttatgtag ctatgtggaa tgatatgtca taatgtaaaa ttagataaat     4140

tcttttttct tataattaat ataacatttc tggacttgaa ctctggcaag agatgccaaa     4200

aggcattggt accgtgttat ttgtttatat gaattacttt ttaacaagga atgtttctta     4260

ttcattaaat gaattcaaca ttttctctgt aaaaacaata gagtttcagt acatgaacta     4320

tagaaaaaaa tctatatata atgtacataa atgttacatt tgtaaagaaa atgtaaaaat     4380

gtaactatag catatgaatt gcttaaactg tgctgcattg ttggatgaca actctttttg     4440

tcacagttag agaatgaggt tgactaatgc atattatgaa ttgagtccac aaaggaacac     4500

aaaactcttt gtaattctgt taaatctttt atgtagattt atttatgatc agcctactaa     4560

ttaaaactat ttcgcttgac agtaaaaaaa aaaaaaaaaa aaaa                      4604


<210>  2372
<211>  396
<212>  DNA
<213>  homo sapiens

<400>  2372
agaagctgtc tatcgggctc cagcggtcat gtccggcaga ggaaagggcg gaaaaggctt       60

aggcaaaggg ggcgctaagc gccaccgcaa ggtcttgaga gacaacattc agggcatcac      120

caagcctgcc attcggcgtc tagctcggcg tggcggcgtt aagcggatct ctggcctcat      180

ttacgaggag acccgcggtg tgctgaaggt gttcctggag aatgtgattc gggacgcagt      240

cacctacacc gagcacgcca agcgcaagac cgtcacagcc atggatgtgg tgtacgcgct      300

caagcgccag gggcgcaccc tgtacggctt cggaggctag gccgccgctc cagctttgca      360

cgtttcgatc ccaaaggccc tttttagggc cgacca                                396


<210>  2373
<211>  2293
<212>  DNA
<213>  homo sapiens

<400>  2373
atcgtttccc cgcgcgcagg tccgcgggga ggggcggcct gccgaccggc ccaccccagg       60

gcgttcctga agggcgtcct cggccgcccc caccgcctcc cagatgtact atgcggtttc      120

ccaggcgcgc gtgaacgcgg tccccgggac catgctgcgg ccacagcggc ccggagactt      180

gcagctcggg gcctccctct acgagctggt gggctacagg cagccgccct cctcctcctc      240

ctcctccacc tcctccacct cctccacttc ctcctcctcc acgacggccc ccctcctccc      300

caaggctgcg cgcgagaagc cggaggcgcc ggccgagcct ccaggccccg ggcccgggtc      360

aggcgcgcac ccgggcggca gcgcccggcc ggacgccaag gaggagcagc agcagcagct      420

gcggcgcaag atcaacagcc gcgagcggaa gcgcatgcag gacctgaacc tggccatgga      480

cgccctgcgc gaggtcatcc tgccctactc agcggcgcac tgccagggcg cgcccggccg      540

caagctctcc aagatagcca cgctgctgct cgcccgcaac tacatcctac tgctgggcag      600

ctcgctgcag gagctgcgcc gcgcgctggg cgagggcgcc gggcccgccg cgccgcgcct      660

gctgctggcc gggctgcccc tgctcgccgc cgcgcccggc tccgtgctgc tggcgcccgg      720

cgccgtagga ccccccgacg cgctgcgccc cgccaagtac ctgtcgctgg cgctggacga      780

gccgccgtgc ggccagttcg ctctccccgg cggcggcgca ggcggccccg gcctctgcac      840

ctgcgccgtg tgcaagttcc cgcacctggt cccggccagc ctgggcctgg ccgccgtgca      900

ggcgcaattc tccaagtgag ggcgggcctg ggcctggggc gcgacctcgg cccggcctcc      960

cttcgctcag cttctccgcg cccctgctcc ctgcgtctgg gagagcgagg ccgagcaagg     1020

aaagcatttc gaaccttcca gtccagagga agggactgtc gggcaccccc ttccccgccc     1080

ccacccctgg gacgttaaag tgaccagagc ggatgttcga tggcgcctcg gggcagtttg     1140

gggttctggg tcggttccag cggctttagg cagaaagtgc tcgctctcac ccagcacatc     1200

tctctccttg tccctggagt tgcgcgcttc gcggggccga tgtagaactt agggcgcctt     1260

gccgtggttg gcgcgccccg ggtgcagcga gaggccatcc ccgagcgcta cctccccgga     1320

gcggagcacg ccggctccca gtactagggg ctgcgctcga gcagtggcgg gggcggaggg     1380

gtggttcttt tccttctcct ccgccagagg ccacgggcgc ccttgttccc gccggccagg     1440

tcctatcaaa ggaggctgcc ggaactcaag aggcagaaaa agaccagtta ggcggtgcag     1500

acggtctggg acgtggcaga cggacggacc ctcggcggac aggtggtcgg cgtcggggtg     1560

cggtgggtag gggcgaggac aacgcagggt gcgctgggtt gggacgtggg tccacttttg     1620

tagaccagct gtttggagag ctgtatttaa gactcgcgta tccagtgttt tgtcgcagag     1680

agttttcgct cttaaatcct gggggtttct tagaaagcaa cttagaactc gagattcacc     1740

tttcgtttcc ctttccccaa aagtagcgta accaacattt aagcttgctt aaaaacgaaa     1800

accaaccgcc ttgcatccag tgttcccgat ttactaaaat aggtaaccag gcgtctcaca     1860

gtcgccgtcc tgtcaagagc gctaatgaac gttctcatta acacgcagga gtaccgggag     1920

ccctgaaccg cccgctgctc ggcggatccc agctgcggtg gcgacggcgg gaaggcgctt     1980

tccgctgttc ctcagcgggc cgggcccttg accagcgcgg cccgcaggtc ttccttctcg     2040

ccgtcttgca gttgaagagc tacatacgta gtcagtttcg atttgttaca gacgttaaca     2100

aattccttta cccaaggtta tgctatgacc tttccgcagt ttactttgat tttctatgtt     2160

taaggttttg gttgttggta gtagccgaat ttaactggca ctttatttta cttctaacct     2220

tgtttcctga cggtgtacag aatcaacaaa ataaaacatt taaagtctga ttttttacaa     2280

aaaaaaaaaa aaa                                                        2293


<210>  2374
<211>  6342
<212>  DNA
<213>  homo sapiens

<400>  2374
gtcgccgaag agcgaacacc ccaaacaatc ccgaagcgcc accaaaaaaa aaaaaaaaaa       60

aaaaaaaaaa aaaaaaaaaa aaaagaaaaa aaaccccgcc ggatccgacc gccactttca      120

aaacccccca ccgctctaga accgcgggag cttccgtccc tgagtagaat tcgagggtgt      180

aaagaagagg aaggggaaaa atatcttgta ccagcccagg ggtgaagaag cccccggcct      240

gagaaagaag gaggagtggg ggaggcgaac agtctcgttg ctgcctctgt gtacgctgag      300

gggggaggtg gccaccgagt actaaattca cttgggaata aaagaaaaac ataagaaaat      360

tataagagaa aggaattgtc ttagaagaaa gaaggcaagc caccatttta cccacgtaaa      420

tatatgaata tatttctgac attgaggtgt tccagaagat gataaagaaa tgatagcagc      480

tccagaaata ccaactgatt ttaatctact acaggagtca gaaacacatt tttcttctga      540

cacagatttt gaagatatcg aaggaaaaaa ccaaaagcaa ggcaaaggca aaacttgtaa      600

aaaaggcaaa aagggcccag cagaaaaggg caaaggtgga aatggaggag gaaaacctcc      660

ttctggtcca aaccgaatga atggtcatca ccaacagaat ggagtggaaa acatgatgtt      720

gtttgaagtt gttaaaatgg gcaagagtgc tatgcagtcg gtggtagatg attggataga      780

atcatacaag catgaccgag atatagcact tcttgacctt atcaactttt ttattcagtg      840

ttcaggctgt aaaggagttg tcacagcaga aatgtttaga catatgcaga actctgagat      900

aattcgaaaa atgactgaag aattcgatga ggatagtgga gattatccac ttaccatggc      960

tggtcctcag tggaagaagt tcaaatccag tttttgtgaa ttcattggcg tgttagtacg     1020

gcaatgtcaa tatagtatca tatatgatga gtatatgatg gatacagtca tttcacttct     1080

tacaggattg tctgactcac aagtcagagc atttcgacat acaagcaccc tggcagctat     1140

gaagttgatg acagctttgg tgaatgtggc actaaatctt agcattaata tggataatac     1200

acaaagacaa tatgaagcag aacggaataa aatgattgga aaacgagcca atgagaggct     1260

agaactcctg ctacaaaagc ggaaagagct tcaggaaaat caagatgaaa tagaaaatat     1320

gatgaatgca atatttaaag gagtgtttgt acatagatac cgtgatgcga tagctgaaat     1380

tcgagctatt tgcattgaag agattggcat ttggatgaag atgtatagtg atgcctttct     1440

taatgacagt tatttaaaat atgttggttg gactatgcat gataagcaag gtgaagtaag     1500

actcaaatgt cttactgctc tacaagggct ttattataac aaagagctta attccaaact     1560

ggaacttttt accagtcggt tcaaggatag aattgtgtct atgacccttg acaaagaata     1620

tgatgttgca gtacaagcaa taaaattact cactcttgtt ttacagagta gtgaagaagt     1680

tctcactgca gaagattgtg aaaatgtcta tcatctggtt tattcagctc accggccagt     1740

agcagtagca gctggagaat ttctctacaa aaagctcttc agtcgtagag atccagagga     1800

ggatggaatg atgaaaagaa gaggaagaca aggtccaaat gccaaccttg ttaagacatt     1860

ggtttttttc tttctagaaa gtgagttaca tgagcatgca gcataccttg tggatagcat     1920

gtgggactgt gctactgagc tgctgaaaga ctgggaatgt atgaatagct tgttactgga     1980

agagccactt agtggagagg aagcactaac agataggcaa gagagtgctc tgattgaaat     2040

aatgctttgt accattagac aagcggctga atgtcatcct cccgtgggaa gagggacagg     2100

aaaaagggtg cttacagcaa aggagaagaa gacacagttg gatgatagga caaaaatcac     2160

tgagcttttt gccgtggccc ttcctcagtt attagcaaaa tactctgtag atgcagaaaa     2220

ggtgactaac ttgttgcagt tgcctcagta ctttgatttg gaaatatata ccactggacg     2280

attagaaaag catttggatg ccttattgcg acagatccgg aatattgtag agaagcacac     2340

agatacagat gttttggaag catgttctaa aacttaccat gcactctgta atgaagagtt     2400

cacaatcttc aacagagtag atatttcaag aagtcaactg atagatgaat tggcagataa     2460

atttaaccgg cttcttgaag attttctgca agagggtgaa gaacctgatg aagatgatgc     2520

atatcaggta ttgtcaacat tgaagaggat cactgctttt cataatgccc atgacctttc     2580

aaagtgggat ttatttgctt gtaattacaa actcttgaaa actggaatcg aaaatggaga     2640

catgcctgag cagattgtta ttcacgcact gcagtgtact cactatgtaa tcctttggca     2700

acttgctaag ataactgaaa gcagctctac aaaggaggac ttgctgcgtt taaagaaaca     2760

aatgagagta ttttgtcaga tatgtcaaca ttacctgacc aacgtgaata ctactgttaa     2820

ggaacaggcc ttcactattc tgtgtgatat tttgatgatc ttcagccatc agattatgtc     2880

aggagggcgt gacatgttag agccattagt gtatacccct gattcttcat tgcagtctga     2940

gttgctcagc tttattttgg atcatgtctt cattgaacag gatgatgata ataatagtgc     3000

agatggtcag caagaggatg aagccagtaa aattgaagct ctgcacaaga gaagaaattt     3060

acttgcagca ttttgtaagc taattgtata tactgtggtg gagatgaata cagctgcaga     3120

tatcttcaaa cagtatatga agtattataa tgactatgga gatatcatca aagaaacaat     3180

gagtaaaaca aggcagatag acaaaattca gtgtgctaag acccttattc tcagtctgca     3240

acagcttttt aatgaaatga tacaagaaaa tggctataat tttgatagat catcctctac     3300

atttagtggc ataaaagaac ttgctcgacg ttttgcttta acttttggac ttgatcagtt     3360

gaaaacaaga gaagccattg ccatgctaca caaagatggc atagaatttg cttttaaaga     3420

gcctaatccg caaggggaga gccatccacc tttaaatttg gcatttcttg atattctgag     3480

tgaattttct tctaaactac ttcgacaaga caaaagaaca gtgtatgttt acttggaaaa     3540

gttcatgacc tttcagatgt cactccgaag agaggatgtg tggcttccac tgatgtctta     3600

ccgaaattct ttgctagctg gtggtgatga tgacaccatg tcagtcatta gtggaatcag     3660

cagccggggg tcaacagtac ggagtaaaaa atcaaaacca tctacaggaa aacggaaagt     3720

ggttgagggc atgcagcttt cactcactga agaaagtagt agtagtgaca gtatgtggtt     3780

aagcagagaa caaacactgc acacccctgt tatgatgcag acaccacaac tcacctccac     3840

tattatgaga gagcccaaaa gattacggcc tgaggatagc ttcatgagtg tttatccaat     3900

gcagactgaa catcatcaaa cacctcttga ttataacacg caggtaacat ggatgttagc     3960

tcaaagacaa caagaggaag caaggcaaca gcaggagaga gcagcaatga gctatgttaa     4020

actgcgaact aatcttcagc atgccattcg gcgtggcaca agcctaatgg aagatgatga     4080

agagccaatt gtggaagatg ttatgatgtc ctcagaaggg aggattgagg atcttaatga     4140

gggaatggat tttgacacca tggatataga tttgccacca tcaaagaaca gacgagagag     4200

aacagaactg aagcctgatt tctttgatcc agcttcaatt atggatgaat cagttcttgg     4260

agtgtcaatg ttttaatacc agtacacaat taaatctgtg gtgaagtcat tttctaagtg     4320

gaagaggaaa ttttaaagtg tggtagatac agtgaaattc tgtacagatt tttctctaag     4380

gagaatatga catgcttatg cttaccaaga tcaagtgcat tgaggggcag ttttgtttgc     4440

ctgaataaac gtaaaggaca agtaaacaat ttgatgataa gctacagttt ttcttagaaa     4500

gtaaatattt tatttatgcg ctgttagttg gcttttgaat cgattatttc atgctttttt     4560

ttaaaaaaaa aaaaaaacaa aataacaatc tgaagaggca tttggtacag atatgaattc     4620

tcttacattt atttactggt tgtactaaat aatgatgacc tctgctggat ttctgtttac     4680

atccagaaaa caatgttaag gatgtattta ttcccctacc ctgaagaaag tgtaggatag     4740

aattgttttt agcattctaa atttaaatgc ttaaaacgtc aatcaacaaa actttgtttt     4800

aaatattgta attgtggaga aaagtaaact tataagcaga acttttacaa ttttttcatc     4860

taaaagtatt ttaagatatt tttaaaatcc aagagcttct ctatactttt cagaaatatc     4920

cagatgcagt gaactgccag aaggtaacca gtctcaaaca tgcttatccc attatcaacc     4980

ctgaaagttt gcttgtcctt taagataaaa atgtaatgtt gtgatattcc ttccagtaat     5040

gccactgtat tttgtctcca aataaaagaa gcttattgta gtatgtttgc agaaaaattc     5100

taaacaaaaa ttatacagct tattagagtg tgggaatagg gatctaaatt ttaaataaaa     5160

ttatatatat atataaattg gtgctgattt tataattgcg cagtttgttt agttttttct     5220

tacttttaaa ttccaactta aaattatgag gtttcagaaa tatattgaaa gtttaacaat     5280

gtttaaaaat agaaaagcat gagtgttcat gctttaaaat gatttttaaa tttgtatttt     5340

atattgtttt atctatctgt ctttgcaagc agtcttcagg ttaaagatac ttctaacagg     5400

ttacagtaca tttcctctgt atgtaaatta gatgggataa tagaattcat aacccataat     5460

attctttgaa agctaagctt taaacttcat tttatgtcct ttcacaaata aattagttta     5520

aaacagaaag tggctacttg ccattttgac atcaactcat tttgcgaggc ttaggcagct     5580

agacatcgtt taaaacaaaa tattaactta tattacatgt gtatctatct attgtcagtc     5640

gtctctcagt tcttgaggta tattatttta atcattccat gccttaatat gcttgcaata     5700

caagaatatc ttcagatggg tgaataccaa aaggctttca gtttttagtc agaaatcaag     5760

cattgggctg tggtagccaa aaaccatagg ttagctaaaa agatcatgat acaattattt     5820

tattaagtca tggttaataa caaatgaatc cagacttgtc taacagattt tccatcaaca     5880

aatattgtta tgtgcaaaag tattgcctat gttgttttac acaccactgc attaactaga     5940

actgctgaga ggactgtata tatgatttta aacctaagtt gatttttttt ctcactcttg     6000

aaaggagtac ttctttgtga aagcagttct tacagctttg ttttcaacca gctaaaaatg     6060

ttttatatat tactctaacc tgttgtcctc cacattctat tgtcctaatt gtactgtttt     6120

ctgatttgta tttatgtctt gagacagtaa ctttttgaat aaaaataaac ctacagtatg     6180

ttgtatgttt tctcttgtac tcaaaggggg agggtggcta taaatggttt gcaaatttat     6240

atctattatc acatctttta atgtgtttgg ggaataattt atagagaata ccatcagttt     6300

atatttttaa taaatcatat gtatttacaa tgaaaaaaaa aa                        6342


<210>  2375
<211>  6897
<212>  DNA
<213>  homo sapiens

<400>  2375
gtccggcggc gtcgcgggcg gcgggcggcg gggccgcggg aggggcgcgg gggcagacaa       60

agccgcggta atgaatggag cgtccgcccg cgccgccgtc gtccgcagcc ggccgggagc      120

cgccccagag gccgggccga ggtaatgcac aagggtcacg tgtatgctct caagatgatc      180

aggcagatcc tgtcctcagg accagaagca cgtctctgct gcacacattg ttgtctacac      240

catgagtgtt tagtagcagg actcttggaa agcagtgatc tatgctgtaa gaccatgagt      300

cacagattct ttttttcagt actatttatg attagccata tttctagaaa catcctgaaa      360

gatggaatta tgacgaaaaa gtgaagataa tctacattcg ggggcacaaa tgagcacttg      420

gatcagtgtt ttatgaacct aagatacagc cggagtagtt atggtcagtc atggagaata      480

acttgaaaac ttgtcccaaa gaggacggtg atttcgtttc tgataaaata aagtttaaaa      540

tagaagagga agatgatgat ggaattcctc ctgatagttt ggaaagaatg gactttaaaa      600

gcgagcagga ggacatgaag cagacagaca gcggtgggga gcgagcgggc ctcggtggga      660

cgggttgcag ctgcaagccc ccggggaagt acttgtctgc agagagtgag gatgactatg      720

gcgcgctgtt ctcccagtac agcagcaccc tatacgacgt ggccatggag gccgtgaccc      780

agagcctcct ttccagccgg aacatgagct ccaggaagaa gtctccagcc tggaagcatt      840

tttttatctc tccccgagac agcactaaag caatatgcat gtactgtgtg aaggagttca      900

gcagaggcaa aaacgagaaa gacttgagta ccagttgtct catgaggcac gtgaggcgcg      960

cacacccgac cgtgctcatt caggaaaatg gcagtgtgtc tgccgtgtcc tcgttcccct     1020

ctccctcact cctgcttcca ccacagcctg cggacgcggg tgacctcagc accatcctct     1080

cacccatcaa acttgtccag aaagtggcgt ctaagatccc gtcccccgat cgaataacag     1140

aggagtctgt gtctgtagtt tcttctgaag aaatctcctc tgacatgtcc gtttcggaga     1200

agtgcggcag agaagaagcc ctggtggggt cgtctcccca cctccctgct ctccattacg     1260

atgaacctgc agagaactta gcggagaaga gccttccact tccaaagagc acctctgggt     1320

ccaggagaag gtccgctgtc tggaagcact tctacctgtc gccactggac aactccaaag     1380

ctgtctgcat tcactgcatg aacgagttca gccgggggaa gaatgggaag gacctgggca     1440

cgagctgcct catcaggcac atgtggaggg cacaccgcgc catcgtgttg caggagaacg     1500

ggggcacggg catcccgcca ctgtactcca cccctcccac tctgctgcct tccttgctgc     1560

cgccggaggg ggagctcagc tctgtgtcct cgtctccagt aaagccggtc agagagtccc     1620

cttcggcctc ctcctcccct gacaggctga ctgaggactt gcagtctcac ttgaaccctg     1680

gagatgggct gatggaagac gtggcggcct tctcatcttc cgatgacata ggggaggcct     1740

cggcgtcctc tcctgagaag cagcaggctg atgggctgag tcctagattg tttgaatctg     1800

gcgccatctt ccagcagaat aaaaaggtca tgaaaagact gaagtcggag gtctggcatc     1860

acttctccct ggcccccatg gacagcctca aggccgagtg tcggtactgc ggctgtgcca     1920

tcagccgggg gaagaagggt gatgtgggca ccagctgcct gatgagacat ctctaccggc     1980

gccatccaga agttgtcggg agccagaagg gcttcctggg tgcaagtctg gcaaactctc     2040

cgtatgccac tttggcctct gcagaaagtt cctcttccaa attgactgac ttgccaacag     2100

tggtcacaaa aaacaatcaa gttatgtttc ctgttaatag caaaaagacc tcgaagctgt     2160

ggaatcattt ttctatttgc tccgcagact ccacaaaagt cgtgtgcttg cactgtggcc     2220

ggaccatcag ccgggggaag aagccgacta acttgggtac cagctgtctt ctgagacatt     2280

tacagcggtt ccatagcaac gtgctgaaaa ctgaggtctc ggagacggct cggccctcct     2340

ctccggacac ccgggtgccg cggggcacag aattatcagg cgcttcctct tttgatgaca     2400

ccaatgagaa gttttacgat tctcacccag ttgccaaaaa aatcacaagt ctcatagctg     2460

aaatgattgc acttgacctc cagccatatt cttttgtaga caacgttggc tttaacaggc     2520

tgcttgaata cttgaaacct cagtactccc tccccgcccc ttcctacttc tccaggacag     2580

ctatcccagg tatgtatgat aatgtgaagc agataattat gtcccacctt aaggaagctg     2640

agagtggtgt gatccacttc acgtctggaa tatggatgag taaccagacc cgtgagtacc     2700

tgaccctcac ggcccactgg gtttccttcg agtcgccagc ccggccgcgc tgtgacgacc     2760

accactgctc ggcgctgttg gacgtgtcgc aggtggactg cgactacagt ggcaacagca     2820

ttcagaagca gctggagtgc tggtgggaag cgtgggtgac ctccaccggc cttcaggtgg     2880

gcatcaccgt caccgacaac gccagcatcg ggaagacgct gaacgagggg gagcactcga     2940

gcgtgcagtg cttcagccat acggtgaacc tgatcgtcag cgaggccatt aagagccagc     3000

ggatggtgca gaacctgctg agcctcgccc ggaagatctg cgagcgggtg caccggtcgc     3060

ccaaggcgaa ggagaaactg gccgagctgc agagggagta cgcgctgcct cagcatcacc     3120

tcatccagga cgtcccgtcc aagtggagca cttccttcca catgctcgag cggctcattg     3180

agcagaaaag ggccattaac gagatgtccg tcgagtgtaa cttccgagag ctgatcagct     3240

gcgaccagtg ggaggtcatg cagtccgtgt gccgtgcgct aaagcccttc gaggctgcga     3300

gccgggagat gagcacgcag atgtccaccc tcagccaggt catccccatg gtacacatcc     3360

tcaacaggaa ggtggagatg ctcttcgagg agacgatggg catcgacacc atgctgcgct     3420

ctctgaagga ggccatggtg agccgcctgt ctgccaccct ccacgacccg cggtacgtct     3480

tcgccacgct gctggatcct cgctacaagg cctccctgtt tacggaggag gaggcggagc     3540

agtacaaaca ggatttaatc agggaactcg aactcatgaa ttctacctca gaggacgtgg     3600

ctgcctccca caggtgtgat gctggctccc cgtcgaaaga ctctgccgca gaggagaacc     3660

tgtggtcact tgtggccaag gtgaagaaga aagacccaag agaaaagctg cctgaagcca     3720

tggtgcttgc gtatctggag gaggaggtgc ttgaacacag ctgtgacccg ctcacctact     3780

ggaacctgaa gaaggcgtcc tggccggggc tgtccgcgct ggccgtcaga tttttgggct     3840

gccccccaag catcgtccct tcagaaaagc tgttcaacac acccactgag aacggtagcc     3900

ttggccaatc caggctcatg atggaacatt ttgaaaaact tatctttttg aaagtgaatc     3960

ttcccttaat atactttcag tattgaaact cacgacggca ccactaggcc agaggcgtgg     4020

ctgccccagc gttagcagcc tgtaccaggt ctatgacccg ctctgcccac ggctgtgtac     4080

gacatcagac caggcactct cagggccgct ctccagctca ccacagtgtc tccacgtgcc     4140

ttaccccttc tccttcaggc caagtttcgc ggggtgtttt attaagacgt ccactagaaa     4200

tagcttgtcc tgtcaactat gaaatatggt gactagattt taattcataa ccgtaaagtt     4260

ttttaaagtt ttgggttagt aatttgtttt actagaatga caaagaagat gtaaaccatt     4320

ttattctgta ggctttttac tcaattatgt acaaaccaca aatcaggtac tgtattttag     4380

tgaagcattg ctttaattgc aacagaatag cttttgtggc tatcaaatga aatctgtaaa     4440

taggaggtgg agggcaagcc atcctgactg agcagttttt aaccgcaggt tctaaagtgt     4500

cccgcggagt acagataata ttctggaagg taactgttta ctacgacaga gacgtggcat     4560

ttggaaacga aacttagatg tttcatggag cttattttga gaactttccc atttcaggtt     4620

tctgcattca ggctttacat ggtcagttaa ctcagagata ccccagctgt ttatcatcag     4680

ctcctctgaa atgtgatccc tttgtaactg tgctcatcac ttcgccagtg cgttcaatga     4740

cacgctgatg gcaggtggtc cctgctgaaa cccccacgcc tccgcttcag catctccacg     4800

ctctgaagct gtctttcaaa atgtgtgcac tgaccccctt gtttgatcaa atttgtgtaa     4860

aattttttta gaagagatgg cttattaaca gggaagaagc ttgttatatt ccagttgtaa     4920

gaatagcctt agtgtttaga tttttttatg atagggaaga tgcggccatc actgggatat     4980

tttcaaatcc caaggacatc agagtgaagt gtcagttgtc agatgatttt aaaagttatg     5040

tcttcagaga aaaaaagatt cattttctca ttttaaacca attaaatatt ctgagtgaga     5100

ctaatcactc atttgcctac gaccttttag aaaagttgtt ttgttgaaat actgtacgta     5160

cgcttaatct aaatttgcat tgactatgtt ttagtgtatt tataaatggt gaactcagtt     5220

tctgaaatta aacttcttat ttgcaatttt ctagtgctgg cagacactgg ctttttattt     5280

ttaggataag aaaacaggca tattctttgt ggtccattat ctagagccca tacttgggca     5340

gcatttgaaa tttcacctta accccagaca gggctccagg gaagtggaga tgtaattctt     5400

acaacaacag ttctgatcat ggccatggtg atgactttcc aggtctcgtg ttcaagtggt     5460

gccagaatgc aggagccggt gggcagccct gaggggttgc cttggccgca gcctctgtgc     5520

acgctcttcc tggtgtcctc ttacccggta gctgtgcgct tgttcccgtg agaacagcct     5580

gcttccagag tgcccaggag tgctggtcag ggacagtgcc cgtgaggctg cagaggaggt     5640

ggggtccatg gcccacccat ctctccctcg ccagcagccc tggccagtgt catcctggtg     5700

tagaaagggt tgcgcacagg ataggaggga gccacagttc ttgcttagct gtgctcacga     5760

ccagcttgca gtcctgtgtt tcttaagatt gtatttggaa tggtaatatc cttagaattt     5820

tgggatattg agcttcatgg attttctctc caaaacaagc cagcacaact aactgtagca     5880

gaattgtatc cactcattca ttcaactgag atgaagtgcc ctcccttttc cagggcctgg     5940

gctagttcct ggaatgcaac agagatttcc gtggacacag tctctagtct cacagagcat     6000

atagtctagt ccacgattgg caagctgcaa ccacagaccc agtccggcac tctgcccatt     6060

tttctaagtg aaattttctt ggaatacagt cacagctgtt tttttaacat ggtgtcttgg     6120

ctactttcag gctgcgacgg gagaactgaa tagttgtgac agagaccaca ggcccactga     6180

aagggacaaa cagggctgaa aatactcact gtttggccct ttccagaata gcaagtttgc     6240

tggcccttga gctagcctgc ctttatgggg ttttttttgt ttgttttttt aagctttcag     6300

cttcatgctg ctgtattttt agttgaagtg ttctgagtaa cagtcagtgt ataaaagggg     6360

attgcagaaa aaaatgaggg cttgctttac tcaacagaaa atatggccct tcctgaatga     6420

cactaggaga gtcattttat ctcatacatt cccttcattt cgttggtgga catttgttga     6480

aaccggcact caatggtcaa accgtctctg ccctccagtt gctgacagtc ctgcaggaag     6540

atggacaaga ggcccagtgc tgacagtcac acgactctca ctacttgaat gaggggactg     6600

tgggtgcaac tagaaaatat gttgattctt agccattccc accttgcctc tccgttcaga     6660

accccagctg cgagctgttt gtttccctgc ctggaaatga tgttttaggc aggttcctta     6720

atttctcagg tctgtctcag ataataaaaa gctctttgta tgagcctcag aactgtctct     6780

tcagtgaatg aaattaccag tcattatacg aagggacttt aaaaaatttg tggaaatact     6840

gaagtaaaag atgataaaaa aataaaaact ttatttcttg gctgggaaaa aaaaaaa        6897


<210>  2376
<211>  2566
<212>  DNA
<213>  homo sapiens

<400>  2376
cattgtctcc gcggcggctg cagccctcga gcgcccgccg cgcgcgcgcg cgcaaccccg       60

gccgccgccc gcgctcccgc cccggcctcg cgcccccgtc ccggcctcgc gccccggccg      120

ccctttgttg acgccggcca ggccggtgcg gtcggatgcg ccgcggcagc cccgggcccc      180

ggctcggagg ctcccggcgg agaggaggcg gcccgcccgg gcccgggacc ccgcgcgagt      240

cggcgcccgg ccgaggggct gcgtaggccc cgcccggcca ggcccagccg ggccctggac      300

agagacaggg cagggcattg ttcatgcact gaccgacctc agcagccccg gcatgacctc      360

agggaacgga aactctgcct ccagcatcgc cggcactgcc ccccagaatg gtgagaataa      420

accaccacag gccattgtga aaccccaaat cctgacgcat gttatcgaag ggtttgtgat      480

ccaggagggg gcggagcctt tcccggtggg acgctcgtcc ctgctggtgg ggaatctcaa      540

gaagaagtat gcacaggggt tcctgcctga gaaacttcca cagcaggatc acaccaccac      600

cactgactcg gagatggagg agccctatct gcaagaatcc aaagaggagg gtgctcccct      660

caaactcaag tgtgagctct gtggccgggt ggactttgcc tataagttca agcgttccaa      720

gcgcttctgt tccatggctt gtgcaaagag gtacaacgtg ggatgcacca aacgggtggg      780

acttttccac tcagaccgga gcaagctgca gaaggcagga gctgcgaccc acaaccgccg      840

tcgggccagc aaagccagtc tgccaccact taccaaggat accaagaagc agccaacagg      900

cactgtgccc ctttcggtta ctgctgcttt gcagctaaca cacagccagg aagactccag      960

ccgttgctca gataactcaa gctatgagga acccttgtca cccatctcag ccagctcatc     1020

tacttcccgc cggcgacaag gccagcggga cctggagctc cccgacatgc atatgcggga     1080

cctggtgggc atgggacacc acttcctgcc aagtgagccc accaagtgga atgtagaaga     1140

cgtctacgaa ttcatccgct ctctgccagg ctgccaggag atagcagagg aattccgtgc     1200

ccaggaaatc gacgggcaag ccctgctgct gctcaaggag gaccacctga tgagcgccat     1260

gaacatcaag ctggggcccg ccctgaagat ctacgcccgc atcagcatgc tcaaggactc     1320

ctagggctgg tggcagccag gattctggcc cagggcgcct cctcccgact gagcagagcc     1380

agacagacat tcctgagggg cccagaaatg gggccggttg gagggcaggg gctctcccta     1440

ggggcatagc tggtgaggag gtctgggcac ctcctccatg gctctcaggg gcctttcatt     1500

tctgtgggag gggcagagag gtaggtggca cagaagatgg ggctttatgc ttgtaaatat     1560

tgatagcact ggcttcctcc aaagtcccaa tactctagcc ccgctctctt cccctctttc     1620

tgtcccccat tttccagggg gtatatggtc agggctcccc aacctgagtt gggttacttc     1680

aagggcagcc agcaggcctg gatggaggcc tagaaagccc ttgccttcct tcctcccact     1740

tctttctcca ggcctggtta actcttccgt tgtcagcttc tcccccttca gcctgtttct     1800

gcagcagcca gggttctccc ccctacaccc tctgcaggtg gagagagaga agctgggccc     1860

agccgggccg tgcctgctgg cacagacgcc ttaacgctgt gtgtatgact gtgtgactgt     1920

gtgggagcct ggactgacag ataggccaag ggctactctc tggcatctcc aggtgttttg     1980

tagcaaacag ccacttagtg ctttgtcctg gactccactc agcctcagga tggggaatag     2040

ccaagaatgg cagcctcagc gcagaggcaa ggtcagaaag agacggcgct tcagagtttc     2100

ctttccagac acccctcccc gcactgtgaa gttcccctga ccgccctcct ggttcacaaa     2160

gagcattaag aaagctgcgg tggtctgagc aacatagccc aaagggctga gcctcctggc     2220

ctgcctgccc gcccaccctg ggagtcccag tggtgaggct cagagaactg ctaaggggaa     2280

agaacagctg gagtttctgt tgatgtgaag aaggcagctc ttggcctccc actcccacac     2340

ttctttgcct ataaatcttc ctagcagcaa tttgagctac ctgaggagga ggcagggcag     2400

aaagggcgag ggcctgcctc tgacctgccg tgtcctttgc aggaaggagg taggcacctt     2460

tctgagctta ttctattccc cacccacacc cccaggcagg gttggaaatg aaggactttt     2520

ttaacctttg ttttgttttt taaaaataaa tctgtaaaat ctgtct                    2566


<210>  2377
<211>  4315
<212>  DNA
<213>  homo sapiens

<400>  2377
gccggaaagg acccggcctc gagatggcag agcggaggcg ttccctgggc tgagctgagc       60

acctcctccc tgagacagca gcggtctaac ccccggcgcg ggagggaccc agccaggggg      120

ctgtcctagt agattccggc attgcctcca ccccgctgtg gcggagacgc agagggcggg      180

tcgcgctcga gggtcaggga ggagagtgac ccggccctgg tccagggccc tccctgcccg      240

ccttggggcc agaactccag ccctggggag tgggcagggc ctgttttccg tgcctcacgc      300

cctgcttttc gcctccttca gcgctgtctg ctagctgctt ttcctgctct ctctccctgg      360

aggcgaaccc ttgtgctcga gatggcagcc accctgctca tggctgggtc ccaggcacct      420

gtgacgtttg aagatatggc catgtatctc acccgggaag aatggagacc tctggacgct      480

gcacagaggg acctttaccg ggatgttatg caggagaatt atggaaatgt tgtctcacta      540

gattttgaga tcaggagtga gaacgaggta aatcccaagc aagagattag tgaagatgta      600

caatttggga ctacatctga aagacctgct gagaatgctg aggaaaatcc tgaaagtgaa      660

gagggctttg aaagcggaga taggtcagaa agacaatggg gagatttaac agcagaagag      720

tgggtaagct atcctctcca accagtcact gatctacttg tccacaaaga agtccacaca      780

ggcatccgct atcatatatg ttctcattgt ggaaaggcct tcagtcagat ctcagacctt      840

aatcgacatc agaagaccca cactggagac agaccctata aatgttatga atgtggaaaa      900

ggcttcagtc gcagctcaca ccttattcag catcaaagaa cacatactgg ggagaggcct      960

tatgactgta acgagtgtgg gaaaagtttt ggaagaagtt ctcacctgat tcagcatcag     1020

acaatccaca ctggagagaa gcctcacaaa tgtaatgagt gtggaaaaag tttctgccgt     1080

ctctctcacc taatccaaca ccaaaggacc cacagtggtg agaaacccta tgagtgtgag     1140

gagtgtggga aaagcttcag ccggagctct cacctagctc agcaccagag gacccacacg     1200

ggtgagaaac cttatgaatg taacgaatgt ggccgaggct tcagtgagag atctgatctc     1260

atcaaacact atcgagtcca cacaggggag aggccctaca agtgtgatga gtgtgggaag     1320

aatttcagtc agaactccga ccttgtgcgt catcgcagag cccacacggg agagaagcca     1380

taccactgta acgaatgtgg ggaaaatttc agccgcatct cacacttggt tcagcaccag     1440

agaactcaca ctggagagaa gccatatgaa tgcaatgctt gtgggaaaag cttcagccgg     1500

agctctcatc tcatcacaca ccagaaaatt cacactggag agaagcctta tgagtgtaat     1560

gagtgttggc gaagctttgg tgaaaggtca gatctaatta aacatcagag aacccacaca     1620

ggggagaagc cctacgagtg tgtgcagtgt gggaaaggtt tcacccagag ctccaacctc     1680

atcacacatc aaagagttca cacgggagag aaaccttatg aatgtaccga atgtgagaag     1740

agtttcagca ggagctcagc tcttattaaa cataagagag ttcatacgga ctaagctgta     1800

attatgatgg ctgagaaatg attcatttga agatacaatt ttatttgata tcaatgaacg     1860

ccctcaagac tgagctgctt ttatcatact ctcctagttg tgggccacga tttaaaccat     1920

cagagatgac aagccatttg aaattctgac cctcagcttt gggaatgtta tctcctccaa     1980

aatggtgatt tttattcact caatgggtta cttcattaaa agcagcccca caagtaactg     2040

gaaatctgaa gaccagggga caaatgctgg tgaatgctta ggcctggaaa tggagtaaat     2100

ctttcaatgt tattttctcc catccttggc ccaaggaact atgctaagtg aaacgtggga     2160

ctgtaatagg gtggtaatgg ctgctttgga aaaaggcaac tagagactct gcctaaattg     2220

ccacacctat tcacacacca tagtagttgg gcacacacat cttcccttcc aaagggcttt     2280

ttccttgagt tgctcatgca tttgtatctt ttccatcttc ctgagggcaa gattttgcac     2340

gatgaaggca atgattgtaa cttttctcct tctcattgtt tctaattagc tcctttaaag     2400

cttgcatctt tgtgaaggct aactgaagat acggttggaa aggaaaaatg agacacaggt     2460

ttggggacca aggacccatc aatgatggtg actttagcag aagatgccca cagttattac     2520

tgccattaat cagatttatg aattttcttt ggggatcact atagggaata ttgtatagaa     2580

aatatcttca agaaaagata ggaccatcag tgacagttaa gtgtaaggag caagtggaat     2640

tgagtccttc agggaaggaa ccacagagtc ccttcccaag gaatgtaggt cgtttctgtg     2700

ttctttccct tctaatcttt aagatcaact cttcctatcc tgctaactct aagatttgat     2760

aagggccaca tcccagtgtt tatcttagct tgcatcaggg catgtgtatg tacagtaatg     2820

tgtattcctg tggtttttct aatagaaact gaatttacag agacttagca tgttcttggg     2880

tgatgtgagt catgtgacag aagtacagac ataactccaa tgtgagaaat gtcctttttt     2940

cattatggaa aataatttaa acactagtgc tttagtgtgc actctcctgt aaggtctgtc     3000

tttgtacaga gctaagcact tgtttgtatg tgtttgtcaa ttgtggaaga taatgaccag     3060

acaaataggt cgattgtcct attctcagaa tgaattatct tctatggtaa tgaagaactc     3120

tttggcttag tcagaaggaa ttaacgaacc tcggtaggaa tgtatttcca tcctcccacc     3180

ctacagatat aagaggttaa aataacagtt cgcccaattt aagcccagta gtgtcagttt     3240

tcctaatctc agtccaggta ggaattaaga aatatctcaa gtgttgatgc tatccaagca     3300

tgttggggtg gaagggaatt ggtgcccaga aaatgggact ggagtgagga atatcttttc     3360

ttttgagagt acccccagtt tatttctact gtgctttatt gctactgttc tttattgtga     3420

atgttgtaac attttaaaaa tgttttgcca tagcttttta ggacttggtg ttaaaggagc     3480

cagtggtctc tctgggtggg tactataatg agttattgtg acccacagct gtgtgggacc     3540

acatcacttg ttaataacac aacctttaaa gtaacccatc ttccaggggg gttccttcat     3600

gttgccactc ctttttaagg acaaactcag gcaaggagca tgtttttttg ttatttacaa     3660

aatctagcag actgtgggta tccatatttt aattgtcggg tgacacatgt tcttggtaac     3720

taaactcaaa tatgtctttt ctcatatatg ttgctgatgg ttttaataaa tgtcaaagtt     3780

ctcctgttgc ttctgtgagc cactatgggt atcagcttgg gagtggccat agatgaccgc     3840

atttccatga cctaactgta tttcaccccc ttttccttcc ctactgttct tgccccaccc     3900

caaccagttc ctgctgctgc ttttggcttc ttggaggtga agggcttaaa acaaggcttc     3960

taagcaccca gctatctcca tacatgaaca atctagctgg gaaacttaag ggacaagggc     4020

cacaccagct gtctcctctt tctgccaatt gttgcccgtt tgctgtgttg aactttgtat     4080

agaactcatg catcagactc ccttcactaa tgctttttgc atgccttctg ctcccaagtc     4140

cctggctgcc tctgcacatc ccgtgaacac tttgtgcctg ttttctatgg ttgtggagaa     4200

ttaatgaaca aatcaatatg tagaacagtt ttccttatgg tattggtcac agttatccta     4260

gtgtttgtat tattctaaca atattctata attaaaaata taatttttaa agtca          4315


<210>  2378
<211>  3212
<212>  DNA
<213>  homo sapiens

<400>  2378
ggccggctgg aggagctgag gttccgagtg cggccgctgc tgggctggcg ggcgggcaga       60

gcacggcacc ctggcagcag ggcccacgcc acggggccat gggcagctcg agccaggcag      120

gctgctgccc acgcttactg ccagggtgac cccagccctg gggcccagcc acaaccaccc      180

tggcttcatg ccaggggctg ctctggttgc cagtcggcca gcctcggggg tgcagcctgg      240

gctgggactg ctgctggggt gcaggtgagg cagtggccgg gccctcaggc cccagggcag      300

gcaggctgca gggagccaag tcctccatgg cggccccagc cgggaaggcg agcaggacag      360

gggctctgcg gcccagggcc cagaaaggcc gggtgaggcg ggccgtgcgc atctccagcc      420

tcgtggccca ggaggtcctg tccctgggcg ccgacgtgct gcctgagtac aagctgcagg      480

caccgcgcat ccaccgctgg accatcctgc attacagccc cttcaaggcc gtgtgggact      540

ggctcatcct gctgctggtc atctacacgg ctgtcttcac accctactcg gctgccttcc      600

tgctgaagga gacggaagaa ggcccgcctg ctaccgagtg tggctacgcc tgccagccgc      660

tggctgtggt ggacctcatc gtggacatca tgttcattgt ggacatcctc atcaacttcc      720

gcaccaccta cgtcaatgcc aacgaggagg tggtcagcca ccccggccgc atcgccgtcc      780

actacttcaa gggctggttc ctcatcgaca tggtggccgc catccccttc gacctgctca      840

tcttcggctc tggctctgag gagctgatcg ggctgctgaa gactgcgcgg ctgctgcggc      900

tggtgcgcgt ggcgcggaag ctggatcgct actcagagta cggcgcggcc gtgctgttct      960

tgctcatgtg cacctttgcg ctcatcgcgc actggctagc ctgcatctgg tacgccatcg     1020

gcaacatgga gcagccacac atggactcac gcatcggctg gctgcacaac ctgggcgacc     1080

agataggcaa accctacaac agcagcggcc tgggcggccc ctccatcaag gacaagtatg     1140

tgacggcgct ctacttcacc ttcagcagcc tcaccagtgt gggcttcggc aacgtctctc     1200

ccaacaccaa ctcagagaag atcttctcca tctgcgtcat gctcattggc tccctcatgt     1260

atgctagcat cttcggcaac gtgtcggcca tcatccagcg gctgtactcg ggcacagccc     1320

gctaccacac acagatgctg cgggtgcggg agttcatccg cttccaccag atccccaatc     1380

ccctgcgcca gcgcctcgag gagtacttcc agcacgcctg gtcctacacc aacggcatcg     1440

acatgaacgc ggtgctgaag ggcttccctg agtgcctgca ggctgacatc tgcctgcacc     1500

tgaaccgctc actgctgcag cactgcaaac ccttccgagg ggccaccaag ggctgccttc     1560

gggccctggc catgaagttc aagaccacac atgcaccgcc aggggacaca ctggtgcatg     1620

ctggggacct gctcaccgcc ctgtacttca tctcccgggg ctccatcgag atcctgcggg     1680

gcgacgtcgt cgtggccatc ctggggaaga atgacatctt tggggagcct ctgaacctgt     1740

atgcaaggcc tggcaagtcg aacggggatg tgcgggccct cacctactgt gacctacaca     1800

agatccatcg ggacgacctg ctggaggtgc tggacatgta ccctgagttc tccgaccact     1860

tctggtccag cctggagatc accttcaacc tgcgagatac caacatgatc ccgggctccc     1920

ccggcagtac ggagttagag ggtggcttca gtcggcaacg caagcgcaag ttgtccttcc     1980

gcaggcgcac ggacaaggac acggagcagc caggggaggt gtcggccttg gggccgggcc     2040

gggcgggggc agggccgagt agccggggcc ggccgggggg gccgtggggg gagagcccgt     2100

ccagtggccc ctccagccct gagagcagtg aggatgaggg cccaggccgc agctccagcc     2160

ccctccgcct ggtgcccttc tccagcccca ggccccccgg agagccgccg ggtggggagc     2220

ccctgatgga ggactgcgag aagagcagcg acacttgcaa ccccctgtca ggcgccttct     2280

caggagtgtc caacattttc agcttctggg gggacagtcg gggccgccag taccaggagc     2340

tccctcgatg ccccgccccc acccccagcc tcctcaacat ccccctctcc agcccgggtc     2400

ggcggccccg gggcgacgtg gagagcaggc tggatgccct ccagcgccag ctcaacaggc     2460

tggagacccg gctgagtgca gacatggcca ctgtcctgca gctgctacag aggcagatga     2520

cgctggtccc gcccgcctac agtgctgtga ccaccccggg gcctggcccc acttccacat     2580

ccccgctgtt gcccgtcagc cccctcccca ccctcacctt ggactcgctt tctcaggttt     2640

cccagttcat ggcgtgtgag gagctgcccc cgggggcccc agagcttccc caagaaggcc     2700

ccacacgacg cctctcccta ccgggccagc tgggggccct cacctcccag cccctgcaca     2760

gacacggctc ggacccgggc agttagtggg gctgcccagt gtggacacgt ggctcaccca     2820

gggatcaagg cgctgctggg ccgctcccct tggaggccct gctcaggagg ccctgaccgt     2880

ggaaggggag aggaactcga aagcacagct cctcccccag cccttgggac catcttctcc     2940

tgcagtcccc tgggccccag tgagaggggc aggggcaggg ccggcagtag gtggggcctg     3000

tggtcccccc actgccctga gggcattagc tggtctaact gcccggaggc acccggccct     3060

gggccttagg cacctcaagg acttttctgc tatttactgc tcttattgtt aaggataata     3120

attaaggatc atatgaataa ttaatgaaga tgctgatgac tatgaataat aaataattat     3180

cctgaggaga ctccaaaaaa aaaaaaaaaa aa                                   3212


<210>  2379
<211>  2632
<212>  DNA
<213>  homo sapiens

<400>  2379
aaagcagtcc tgcacttcca gttgtgagcc aagagccaag tgtgggagct caccatggtg       60

gcagccacct ccccaccaag caggcagcgt tcaccagagg ggagtatcag gttcctgtac      120

tcagctgtgg gttgtcactg tctaataata tgaccgtttt gccatctctc tgcaaatgag      180

gctgaagctg ctatctgatt ggtataacat ctcactttcc ctctgcattg attttcttct      240

tctcctcctt tgcttcataa aaagagggac aagtggctgg tgctgtggac agagaagctt      300

tatttttagt atgagacaac ctctattttc tttcaggaga gggaagttgg attatcaatt      360

cttttgtaaa tgtgtatggt gatatttgct ccgctttttg caatctttgc atttgcaaca      420

tgcggtggct attctggagg cctgcggctg agtgtggact gcgtcaacaa gacagaaagt      480

aacctcagca tcgacatagc gtttgcctac ccattcaggt tgcaccaggt gacgtttgag      540

gtgcccacct gcgagggaaa ggaacggcag aagctggcat tgattggtga ctcctcgtct      600

tcagcagagt tcttcgtcac tgttgctgtc ttcgccttcc tctactcttt ggctgccact      660

gtcgtttaca ttttcttcca gaacaaatac cgggaaaaca accggggccc actcattgac      720

ttcattgtca ctgtagtctt ttcgttcttg tggttggtgg gttcatcagc ttgggcaaaa      780

ggactgtctg acgtcaaagt tgcaacggat cccaaggaag tattgctact aatgtcagct      840

tgcaaacagc catccaacaa atgcatggct atccacagcc ctgttatgtc aagcttaaac      900

acttctgtgg tctttggatt cttgaacttt attctctggg ctggaaacat atggtttgtt      960

ttcaaggaga ccggctggca ttcttcggga cagagatatc tttcagatcc aatggagaag     1020

cactccagca gctataatca aggtggttac aaccaagaca gctatggatc aagcagtggg     1080

tacagtcagc aggcgagttt ggggccaacc tcagatgagt ttggccaaca gcctactggc     1140

cccacttcct ttaccaatca gatttaacag agtagcattt gcattcttct gcagtcgcct     1200

caccatcttc catttcagtg gcagaagaat tttttaaggg tttcaatcaa ttattaatgc     1260

agagagtatt gaatgtaaat cagagctctc tagtcttcat taaggcagca agtcctgggt     1320

tgtgaaaaat gatacttaga gatgaggcga catgaggaga tatattattc atcatagatg     1380

gctaattgga gagtaccttg ttatatatac agatactttc atggtcattt tgtatgtatg     1440

ttaaagtagt agaagtattt tgtagcttaa agtctctagt atgtaatatg cataaagtaa     1500

atcaaatagc gttgagtttt cttatgcatt ttgatgtgaa agatgttata ataatttcta     1560

gaagacaatt tggtgtatca caacatgcat gtcttatttt tttttagttt taagtcctat     1620

aggactatga gtctctaagt tatttgtttc agaaaattat tcttttttta tgtgataaat     1680

catatgattt aagtgcatga ataagcattt tcccacacaa tgaacatttg aactgtgttt     1740

atgaaaattt tctggtttgc accatgaatt tgtcaaatgg atatttatag gaatatattc     1800

actactttgt atactttgca aatttgtctc tctggcttta cccaagttct gaatgcattg     1860

taattaaaat ttaagttttt cttttccccc attagtaaac atttagtgct acatatgata     1920

actgcccaat atttattcta tttacttagc taaatatttg cattcttgta accttctatg     1980

gtgttttgtg gctcttatct tgtggaccat aaataacacg gcccaataac tctttgtgtt     2040

tatggagtgt tgttttctta gaataatgga gatgcagata tagataccat agtcaaggta     2100

ccgccttgct gaagtattta tttataaaga atattctgta gaacctctac taccagctat     2160

atttttaaat cctgtttatt tgtaaagcta atatgctcct caatgtaatt attaaaaatt     2220

ctcaagtcac agctaaactt actaattctg attttagtgt agcccctaaa ttaaaaatgg     2280

cttccatatg ccactctgta ccccaaagag agttctcatg aaatattctc cagaatgtat     2340

tcattatcaa gaaaatgtca atcgtcactt cctcgtttta actcagctga aacaccagga     2400

cccaatagag agggcaagct gagcatctgt atttccagat aaaagttgtt attgatgtat     2460

aaactcgttg cgtgattagt gatgttggaa gcattttagc acaaaacagc cttgtgtctt     2520

agatgatatc tgtaaccagt ttctgaatcc cgttggataa aactgtattg tgatatctat     2580

ttgatgttaa taaagttatt gcatacaaaa aaaaaaaaaa aaaaaaaaaa aa             2632


<210>  2380
<211>  3674
<212>  DNA
<213>  homo sapiens

<400>  2380
gggcctactc tgccgccgcc gccgcccgcc cgctccagcc gccgccgccg ccgccaccgc       60

cctccaggct ccgggacccg gcccgcgcca ccgcccccgt gcgcgccccg ccgccgccgc      120

cttcgccttc gccttttgtt tcctccgctc cggcgccccc gccccggctc gcgctttgca      180

ggggacgcag cgcgcgcccc cagcgggccc gggaaaagcc gcggcgcgcg cgcgcgcctg      240

cgcggcggac ccctccttct cctccccgcg tgcgcgtgcc cttcttggct gcgcgccggc      300

gccgcctggc gggcgggagg ggaggtggca ggcgcgtttg caggaggggc gcacctcttc      360

gctcgcgcac ccccccggaa ggtagaccgg gaaggggagg cgggcgggcg gagaggagag      420

agtggcgcgc agtccagcga gggcgggggt tggctatgtg gggggtggtg caccccgcag      480

tctagacagt ctgatccggg ctgggggcgt gtacactcgg cgcacctgcg agactacaga      540

gcctcgggcc ggcacgtgtg gggagtgtgg acacgtctgc tgcgccccgc ttctcgctgc      600

tgaggggaag ggagggggcg ggcaggtgca gcggccgggc tagtgggagg gggcggcggc      660

catggagcgg gtgaacgacg cttcgtgcgg cccgtctggc tgctacacat accaggtgag      720

cagacacagc acggagatgc tgcacaacct gaaccagcag cgcaaaaacg gcgggcgctt      780

ctgcgacgtg ctcttgcggg taggcgacga gagcttccca gcgcaccgcg ccgtgctggc      840

cgcctgcagc gagtactttg agtcggtgtt cagcgcccag ttgggcgacg gcggagctgc      900

ggacgggggt ccggctgatg tagggggcgc gacggcagca ccaggcggcg gggccggggg      960

cagccgggag ctggagatgc acactatcag ctccaaggta tttggggaca ttctggactt     1020

cgcctacact tcccgcatcg tggtgcgctt ggagagcttt cccgaactca tgacggccgc     1080

caagttcctg ctgatgaggt cggttatcga gatctgccag gaagtcatca aacagtccaa     1140

cgtacagatc ctggtacccc ctgcccgcgc cgatataatg ctctttcgcc cccctgggac     1200

ctcggacttg ggcttccctt tggacatgac caacggggca gccttggcag ccaacagcaa     1260

tggcatcgcc ggcagcatgc agccagagga ggaggcagct cgggcggctg gtgcagccat     1320

tgcaggccaa gcctctttgc ctgtgttacc tggggtggac cgcttgccca tggtggctgg     1380

acccctatcc ccccaactgc tgacttcccc attccccagt gtggcatcca gtgcccctcc     1440

cctgactggc aagcgaggcc ggggccgccc aaggaaggcc aacctgctgg actcaatgtt     1500

tgggtcccca gggggcctga gggaggcagg catccttcca tgcggtctat gtggtaaggt     1560

gttcactgat gccaaccggc tccggcagca cgaggcccag cacggtgtca ccagcctcca     1620

gctgggctac atcgaccttc ctcctccgag gctgggtgag aatgggctac ccatctctga     1680

agaccccgac ggcccccgaa agaggagccg gaccaggaag caggtggctt gtgagatctg     1740

cggcaagatc ttccgtgatg tgtatcatct taaccggcac aagctgtccc actctgggga     1800

gaagccctac tcctgccctg tgtgtgggtt gcggttcaag agaaaagacc gcatgtccta     1860

ccatgtgcgg tcccatgatg ggtccgtggg caagccttac atctgccaga gctgtgggaa     1920

aggcttctcc aggcctgatc acttgaacgg acatatcaag caggtgcaca cttctgagcg     1980

gcctcacaag tgtcagacct gcaatgcttc ttttgccacc cgagaccgtc tgcgctccca     2040

cctggcctgt catgaagaca aggtgccctg ccaggtgtgt gggaagtact tgcgggcagc     2100

atacatggca gaccacctga agaagcacag cgaggggccc agcaacttct gcagtatctg     2160

taaccgagaa ggccagaaat gctcacatca ggatccgatt gagagctctg actcctatgg     2220

tgacctctca gatgccagcg acctgaagac gccagagaag cagagtgcca atggctcttt     2280

ctcctgcgac atggcagtcc ccaaaaacaa aatggagtct gatggggaga agaagtaccc     2340

atgccctgaa tgtgggagct tcttccgctc taagtcctac ttgaacaaac acatccagaa     2400

ggtgcatgtc cgggctctcg ggggccccct gggggacctg ggccctgccc ttggctcacc     2460

tttctctcct cagcagaaca tgtctctcct cgagtccttt gggtttcaga ttgttcagtc     2520

ggcatttgcg tcatctttag tagatcctga ggttgaccag cagcccatgg ggcctgaagg     2580

gaaatgaggc agctgctgtg tccccacgga aacaaccatc tggggactgc tgggaaatgc     2640

tgtgaatgcg gagggaagtg atgtttgggt tctgtagctg agagattttt attcattttt     2700

aactgccccc caaccccact ccaactcctt ctccaccacc cattctccca atggtcttta     2760

gaaatagatt ttcatctgat attctgcaga aatatcaatg agacttggta tgggacaggg     2820

gcagaaaaca ctacataggc ctccaaggca aaaccagtcc cagtttcttt aatgggaaga     2880

agctggaatt cctggtgctc aattcttagt gaccccaatc ctatacccaa atctatgata     2940

ttctgggacc tcagtgattt tggtcccctc ccacttctct agttcgtcat cctcccttcc     3000

catatccttc aaaagaacca cactagggtc tccacctact tatacaatgc ggatgcccaa     3060

ctgtttttaa ggaagccaga agcatcccat ggaccatggg gtgagtgtcc tccaagagcc     3120

ccctgagctc agccctctgc ctggagggct ccagaccttt ctgagccctg cttggaggcg     3180

agcattttca ctgctaggac aagctcagct gttgaggaca cccccacccc aaatttcagt     3240

tcttacgtga ttttaaccat tcaacatgct gttgggtttt aattctctaa ttattattat     3300

tattgttatt attttttagg accagttgta gtgaattgct actgaaagct atcccaggtg     3360

atacagagct ctttgtaaac cgcagtcaca cattagggtt agtattaaac tttgtttaga     3420

tgtaccataa ttaacttggc tagttgattg tttgaagtct atggaagaaa tagttttatg     3480

caaaatttta aaaaatgcca gtctggtcag ggaagtaggg ggtttcaatg ctgttgggaa     3540

ccaggaaggt gggacagccg gcaggtaggg acattgtgta cctcagttgt gtcacatgtg     3600

agcaagccca ggttgacctt gtgatgtgaa ttgatctgat cagactgtat taaaaatgtt     3660

agtacattac tcta                                                       3674


<210>  2381
<211>  7190
<212>  DNA
<213>  homo sapiens

<400>  2381
cttttagttt ctcttctttc taaagaaggc tcgcggagcc cggctggaga acctcaccct       60

cgccgagcct agaaccgaga gggggccacc ccaggcggtc accagcagat ttgcccgcgc      120

gttctctttc tttccaccca gttgcccttg cggccggctg taaacctgcc actaggaccc      180

ggtcggtgag atctagcctc ttgacctgag agccgagagt ggatcgctgg gctgggctaa      240

cggcgacgga gagcgcgccc tcgctgactc cgggcgcgcc cagcagtagc accgcccgcg      300

cccgcccctg gacacttgta agtttcgatt tccgatttcc gcggaaccga gtcccgcgcc      360

gcggcagagc cagcacagcc agcgcgccat ggcggacccg gaggtgtgct gcttcatcac      420

caaaatcctg tgcgcccacg ggggccgcat ggccctggac gcgctgctcc aggagatcgc      480

gctgtctgag ccgcagctct gtgaggtgct gcaggtggcc gggcccgacc gctttgtggt      540

gttggagacc ggcggcgagg ccgggatcac ccgatcggtg gtggccacca ctcgagcccg      600

ggtctgccgt cgcaagtact gccagagacc ctgcgataac ctgcatctct gcaaactcaa      660

cttgctgggc cggtgcaact attcgcagtc cgagcggaat ttatgcaaat attctcatga      720

ggttctctca gaagagaact tcaaagtcct gaaaaatcac gaactctctg gactgaacaa      780

agaggaatta gcagtgctcc tcctccaaag tgatcctttt tttatgcccg agatatgcaa      840

aagttataag ggagagggtc ggcagcagat ttgtaaccag cagccaccgt gttcaagact      900

ccacatctgt gaccacttca cccgagggaa ctgtcgtttt cccaactgcc tccggtccca      960

taacctgatg gacagaaagg tgctggccat catgagggag cacgggctga accccgacgt     1020

ggtccagaac atccaggaca tctgcaacag caagcacatg cagaagaatc ccccagggcc     1080

cagagctcct tcttcacatc gtagaaacat ggcatatagg gctagaagca agagtagaga     1140

tcggttcttt cagggcagcc aagaatttct tgcgtctgct tcagcgtctg ctgagaggtc     1200

ctgcacacct agtccagatc agatcagcca cagggcttcc ctggaggacg cgcctgtgga     1260

cgatctcacc cgcaagttca cgtatctggg gagtcaggat cgcgctcggc ctccctcagg     1320

ctcgtccaag gctactgatc ttggaggaac aagtcaggcc gggacaagcc agaggttttt     1380

agagaacggc agtcaagagg acctcttgca tggaaatcca ggcagcactt accttgcttc     1440

caattcaaca tcagccccca actggaagag cctcacatcc tggacgaatg accaaggcgc     1500

caggagaaag actgtgtttt ctcccacgct acctgccgcc cgctcttctc ttggctctct     1560

gcaaacacct gaagctgtga ccaccagaaa gggcacaggc ttgctttcct cagactacag     1620

gatcatcaat ggcaaaagtg gaactcagga catccagcct ggccctcttt ttaataataa     1680

tgctgatgga gtggccacag atataacttc taccagatcc ttaaattaca aaagcactag     1740

cagcggtcac agagaaatat catcacctag gattcaggat gctggacctg cttcccgaga     1800

tgtccaggcc actggcagaa tcgcagatga tgctgaccca agagtagcac ttgttaacga     1860

ttctttatct gatgtcacaa gtaccacatc ttctagggtg gatgatcatg actcagagga     1920

aatttgtctt gaccatctgt gtaagggttg tccgcttaat ggtagctgca gcaaagtcca     1980

cttccatctg ccttaccggt ggcagatgct tattggtaaa acctggacgg actttgagca     2040

catggagacg atcgagaaag gctactgtaa ccccggaatc cacctctgtt ctgtaggaag     2100

ttatacaatc aattttcggg taatgagttg tgattccttt cccatccgac gcctctccac     2160

tccttcttct gtcaccaagc cagccaattc tgtcttcacc accaaatgga tttggtattg     2220

gaagaatgaa tctggcacat ggattcagta tggagaagag aaagacaaac ggaaaaattc     2280

aaacgtcgac tcttcatacc tggagtctct ctatcaatcc tgtccgaggg gagttgtgcc     2340

atttcaggcg ggctcacgga actatgagct gagtttccaa gggatgattc agacaaacat     2400

agcttccaaa actcaaaagg atgtcatcag aagaccaaca tttgtgcctc agtggtatgt     2460

gcagcagatg aagagagggc cagaccatca gccagcaaag acctcgtcag tgtctttaac     2520

tgcgaccttt cgtcctcagg aggacttttg cttcctatcc tcaaagaaat ataagttgtc     2580

agagatccat cacctacatc cagaatatgt cagagtaagt gagcatttta aagcttccat     2640

gaaaaatttc aagattgaaa agataaagaa gatcgagaac tcagagctcc tggataaatt     2700

tacatggaag aaatcgcaga tgaaggaaga aggaaaactc ctattttatg cgacaagccg     2760

tgcctatgtg gaatctatct gttcgaataa ttttgacagt ttcctacatg aaactcatga     2820

aaacaaatac ggaaaaggaa tttactttgc aaaagatgcc atctattccc acaaaaattg     2880

cccgtatgat gccaaaaacg tcgttatgtt tgtagcccaa gttctggttg gaaagtttac     2940

tgaaggaaat ataacgtaca cgagccctcc tccacagttc gacagctgtg tggataccag     3000

atcgaatccc tccgtttttg tcatctttca gaaagatcag gtttacccac aatatgtgat     3060

tgaatatact gaagacaaag cctgcgtgat tagttagaac cgatgaatac agcgtcagaa     3120

ggatgccata accattctgt tcctttacag aactaaattg ccgcagacag gagttaaagt     3180

tttatatttt cctgctcagt tatctaatgt cttagatcag tggtccccaa attttgctac     3240

atattagaat catctgggag gttttaaaca aattctgatg cccaggttgc accccatgcc     3300

aatgaaatca tttctgggcg tcagcgccag gcagttgtat tttttttttt tttttttttt     3360

ttgagactga atctcactcc atcgtccagg ctggagtgca gtggcgcgat ctcggctcac     3420

tgcaacctct gcctcccggg ttcaagcaat tctcctgcct cagcctcccg agtagctgga     3480

actacaggca cacactgccg cgcccagcta attttttgta ttttttagta gagacagggt     3540

ttcactgtgt tgcccaggct ggtctcaaac tcctgagctc aggcaatctg cccgccttgg     3600

cctcccaaag tgctaggatt acaggtatga gccaccatgc ccggctggca gttgtatttt     3660

ttaaagccct tctgatgatt ccaatgtgtt ggaaagttta ccttgtctca gatgtaactg     3720

gtaaaggctg atttctaaat tttctgtaat tgcagcaacc tttctctcct gtctaccctt     3780

ttagtttact gtatgccatg gttttgtttt ggttacattg aaagaaagtt aatttggaaa     3840

atttgggaga aatctaatca tgcctattaa ggatgtaaga cattacagcc ttagaagaaa     3900

gattgtgaaa agctggggag aaaatgctta aggacatgct aggggaaaaa aaagtaaaat     3960

tgaagtgcta ttgcagacat ggctgcagta ctgtacctta tcattctgat gaaactgatt     4020

tggagcaccc ttttctttat cgctacattt atttagggga caaactccat ccaggttgac     4080

tctctctgga atgcggtaat aagagctggc aagtaaggct cagagagaag caaccaactg     4140

gagttaattg cccatttggg ctctttgtat aattatggca aagtagacat ttatgttcta     4200

attaatatga ttacagagaa ggctttttct caggtcaggc ttttcatgaa agtattttga     4260

gaacaatgaa ttgcaataac cagcttcaca caagcataac tgataaacgc gagtgctatt     4320

gtagtcttgg caagtgagcc aagaacctag gagcagggcc attcctactg aaggacgggc     4380

cccctacgga gatgaaattt gtttcctggt gagcacagaa tcagaacaaa gaacaatatc     4440

ccaaagaggc cctgtgtcta ccaggagctt ctttttccaa atgtaatgga ttatgtggaa     4500

ttgtagtgcc atcggttttt acttagagcc cttgacgtgc ttggaccaat atttccttcc     4560

ttcttatgaa ccaggttttt ccttctgatt ttcccttttc aacattcctt accagtcacc     4620

aaagtttcct gttataattt cttttagcag acaagttata agtcagattt aattagcatc     4680

agagttgatt ttatattagt cagattttgg atcatcacag agatctccac aactccttgg     4740

cttaaacagc tccaccggta aaaaaaaaaa aaaaaaaaaa aaaaaaaaat agttttttta     4800

gagtagagtt attttctggg agagttacta caaatgctta ttctcattga cttatttctt     4860

tcatggtaac tttcgttttg gagtgttcat tttctgaact tgaccctcac attgtagggg     4920

tgcagtttgt ccaactcttt ccaacagccc attagacacc actagctgga tatttcacag     4980

gcatctttga ttcaatatgt ccaaagtgga actctccatc tacctccctc acatgaacct     5040

gttcctctct caggatctgt atgtaagtga aaagcatcac catctaccca ttggctcaag     5100

cagaaatctg gaagtcatct ttgactcctt cctctccctc ctgataaaca tctaagcagt     5160

ttctaagtct agttttacct cttaaatatc tctgttccct tctaagttgt ttgctgtgtt     5220

ttcttcagag caagaaggtt atatttttta aaatttactt agtaatgcac attcaaaaca     5280

cacatcaagt cttcaggata aagttcaaaa ccgctgtcat ggccccatgt gatctctccc     5340

tcccctaccc ctctatcatt tagtttcttc tgcgcaagcc actctggctt cctttcagtt     5400

ttgtggttcc catttttagc tagttcagtg gttttcaatg ggcatttctg cctttttttt     5460

tctaaacgac aaatagaaat acatcttctt tattatcctc caaatccaat tcagaggtaa     5520

tatgctccac ctacacacaa ttttagaaat aaattaaaaa ttaaataaaa ctaatatgaa     5580

cataaagagg aaataaaagg tacctaactt gggcacagct gtaactgaag acctaatgaa     5640

gtagtcagat gcttacaact atttataatg catcaatttg aacttagaag gtaggagatc     5700

agatcatatg tgggaaaatg taaaagcagg gatatcagtg ggcattagaa taaaaactag     5760

ggatacaata acttctttgc atatgacaat acttatttgt atataagaga aagaacgaaa     5820

taacctttat tgaaataaag atactatgca agaaaatgta cagttgtcga agtggagaaa     5880

atgaggatat attcttgcag acgagctata ggtcatacat gaatgtctag tgagacattc     5940

aaaattcgta tagggtgcag agtaatttct tattgtgagg aactgtccaa tgtattgcaa     6000

gatgttctgc atacttggct ctcacatact aaatgctagt agcgccccca cccccacgcc     6060

cagtcacggt gacaaccaca aaccctatca gatctattca cctttttcag agcagatatt     6120

ttgtaacatt ctctttgctg acctgaaatg actcatagat aatacaatct acttacacac     6180

atgaatttct taaaaaaatc aatttaatgc cctaactctc ttattaagga gaaatagaaa     6240

agaagaaatt tataatgaaa agaagatgaa tttcattatg taaacgctca ggcatgacta     6300

cgctgtttga aacagacaga tgtttactct tccttgtaat gagtaggttt ggatttaaga     6360

gccgattaga ggctacttcc tgtaaacaag tacaggaaaa tgaaactaga cgggtggggg     6420

acactagaat gaaaaccagt gttagggtaa agacaaaaca gactatgtac ataatctgta     6480

tatgggaaaa gaaagagcga aattacctta cttaaggata ataggacaag acaaattaca     6540

gattgtctca gagaaaacaa atgagttact ctctcggaca agctgtaggt cctacctaaa     6600

tgtccagcag gacattagac agtcgtacag ggtacagaat aattcttcgt tgtgtggcac     6660

taacccacac actgcaggac atcgttctcc ctggctgcat ccactcagtg ctgggagtag     6720

tccccagtta ttatgaaacc accaataacc cactgaccac agtgagaacc actgattttt     6780

tccactgacc tactgaatat ctagcatcct tagattggct caactgttac tttcctaagg     6840

agtccttcta cagaataggt cagatcttgg cctcccaaac cccttatttt taaaatactt     6900

tgcgccttgc tttgataatt tgtattatgt atccaaactg aaattatctg ctttctgcat     6960

tagaatgtaa gccccctgag ggttgagtca gtctgtcttg tttgctgtgc cacgcctgat     7020

gcccagccca gcagcatgct ttgtacactg atatattggg taaattttgt tgaataaatt     7080

aagctcaact atttgtattt caatagttga gttgtattgc ttcctgttct tcaagcttaa     7140

tttgaactgt ctaataaaaa gaagtaatta aaaaaaaaaa aaaaaaaaaa                7190


<210>  2382
<211>  4625
<212>  DNA
<213>  homo sapiens

<400>  2382
atacctacac cggctttttg tacgactgtt ggccctggag aacgatcctt tggtggcgag       60

ggcggggagg acgaaagcgc ccactgtgga ttggacagtg tcaaaaagag gggcggtccc      120

tactgaaggg gcggttgggc gacgaaggga agagtctttt cagcgctgag gactggcgct      180

gaggaggcgg cggtggctcc cggggcgttt gagcgggctc acccgagccc gcgggccaac      240

gcggatccag gcccgactgg cgggaccgcc ccggattccc cgcgggcctt cctagccgcc      300

atggaggacg gcgtctatga acccccagac ctgactccgg aggagcggat ggagctggag      360

aacatccggc ggcggaagca ggagctgctg gtggagattc agcgcctgcg ggaggagctc      420

agtgaagcca tgagcgaggt ggaggggctg gaggccaatg agggcagtaa gaccttgcaa      480

cggaaccgga agatggcaat gggcaggaag aagttcaaca tggaccccaa gaaggggatc      540

cagttcttgg tggagaatga actgctgcag aacacacccg aggagatcgc ccgcttcctg      600

tacaagggcg aggggctgaa caagacagcc atcggggact acctggggga gagggaagaa      660

ctgaacctgg cagtgctcca tgcttttgtg gatctgcatg agttcaccga cctcaatctg      720

gtgcaggccc tcaggcagtt tctatggagc tttcgcctac ccggagaggc ccagaaaatt      780

gaccggatga tggaggcctt cgcccagcga tactgcctgt gcaaccctgg ggttttccag      840

tccacagaca cgtgctatgt gctgtccttc gccgtcatca tgctcaacac cagtctccac      900

aatcccaatg tccgggacaa gccgggcctg gagcgctttg tggccatgaa ccggggcatc      960

aacgagggcg gggacctgcc tgaggagctg ctcaggaacc tgtacgacag catccgaaat     1020

gagcccttca agattcctga ggatgacggg aatgacctga cccacacctt cttcaacccg     1080

gaccgggagg gctggctcct gaagctggga gggggccggg tgaagacgtg gaagcggcgc     1140

tggtttatcc tcacagacaa ctgcctctac tactttgagt acaccacgga caaggagccc     1200

cgaggaatca tccccctgga gaatctgagc atccgagagg tggacgaccc ccggaaaccg     1260

aactgctttg aactttacat ccccaacaac aaggggcagc tcatcaaagc ctgcaaaact     1320

gaggcggacg gccgagtggt ggagggaaac cacatggtgt accggatctc ggcccccacg     1380

caggaggaga aggacgagtg gatcaagtcc atccaggcgg ctgtgagtgt ggaccccttc     1440

tatgagatgc tggcagcgag aaagaagcgg atttcagtca agaagaagca ggagcagccc     1500

tgaccccctg cccccaactc cattatttat tacggagctg ccccgcctgg gtggccggac     1560

ccctgggcct tggggctgtg gatcctggtt ccctgtttgg aaaattcacc acctctagct     1620

cctcactgtt ctttgtaatt aacacgctgt tggtaatctt attaattatt taaccacttg     1680

gcctgctgac cccctcattt cttggggttg acagagtcga ggtgctccgt ggagccagcc     1740

tgtttccctg gacaggggcc tggacccgcc tgtctctggg tgctgcctgg gctgtcccgg     1800

tgggtctgtt ctggtttcac cccgagccca gcaggagtgg agtaaaggga gaaggttaat     1860

atggtgggag tctggagttg gaattggccg gggacagagt ttagaatgca gggattcagg     1920

gtcaaggtct agcattcatt ctagaagtta cttgacagcc atcagccagt tacgctacag     1980

ccatcagcta gttcccatcg ttgctttcat ggggcttgag gtctttgagg ggcaggagat     2040

gaagctggtg aggttgtgag ctgggccagg gctttgagga caacctggag ctggaagaac     2100

atgcgaccac ctcagggagg gtcagggaag gatgagtggg gaggtggccc atgtcctgca     2160

agggccttgc tgatgggatg tcctgaaggg ctgggcagcc ttagatcggg ctaagagggc     2220

aggactgtgg gccagtgcca gagccaggct tgtctgttct caaaggatca gcctcctttg     2280

gaggacattt tgtgtcaagg atagggctga ggacctgcgt tctgaacgtc tttcctggga     2340

ttcttgacag ccaaagaaat tcgaggatcg cctctatgaa ggtgaagtct tggcatgtgg     2400

ggtacccctg aatcctgggc taaggtctgt gaccttttgc cctccagttg gggtatgtgt     2460

ggtgtcccca aagaacaagg gctcgtggat cccgagcagg gtgcgatggc ggattgggag     2520

gtcccatgtc actctcccat gcccgccttt gaagctgagg cgctctttag ttaacaaact     2580

acaagtccca gcagggaccg ggacgcgggt gggagaggcg cctgtggccc cgaggcgtgc     2640

cgcgagttgt agtccctcct gcccgctgtg ttcgcttttg agctctccga tgggatgcgg     2700

cgcttcggaa tttcgggctt tgatccctgt cccgcccttg gccacaggca cctgccggcc     2760

tgaaggcccc cgcggtgggg gtaccctgcg cccctccgcg ggaaggtgga ctacagttat     2820

cggcaggctg tgcggcgcca aagccacggt gacccagacc cgaggttttt ccgggcgtcg     2880

cagtttcccg agactccgtg gcggcgtttg tcttcttttt cttagtcaga tcccgtactt     2940

ttgtggaggg tagaggaggc tttgaccgcc gcggccccgg gggctggtgg gaaatggagt     3000

tccaaatgag aaaatagaat tccccacttc tctttcccac aggtgccagg gaaacggagt     3060

catcgaccca agaaggtcgt gggagatgag gtcccagggt aaacagcggg tcccgccact     3120

atgtcaccct ttcctgccgc ctccccggat gaactgcatg cagggcggcc ggctccgtgg     3180

caggcagagg caggaagagg cgcggagccc gctggtggcg aagaggggag tgcggcggga     3240

ggggagggca gaggcaggcg gccggtcgcg tggggcctgg gccgccccag gagggcctct     3300

ggctggattc ttagcagatg gaagccgtgc aagggcagga ggcaggggcc tgacgtgttt     3360

ggattgaggt tgcaggaggg gcccctggct gcttcaggga gaataatttg gaggcgagcg     3420

gggaggtgag aggaagctgt gcggtgcagg atggcgtggc tgtggaggtg gagaacgttg     3480

ggccacgcta ggagtcttga aagaggagcc aaaaggactt gctgagagcc gccgcagctg     3540

gtgaatgacg gtgccatgac tgaggtggtc gaaagggagt atttaagggg aaatcaggca     3600

ttccgttttg accaaattaa gctggagatg cctgtggaac attccagcca ggctgcatca     3660

cgtcacactg accttcagca ttgcccacag tccatcttcc cccaggacct gaggattttg     3720

cgtccggctc cctcctcgcc caggaccccc aagctcccag cacgcttctg attttttttg     3780

taggtttttt tttttgtttt ttgttttgtt ttgttttgtt tttgagaggg agtctcactt     3840

tgtgccctag actggagtgc aatggcgcca tctcggctta ctgcaacctc cacctcccag     3900

gtgcaagcga ttcccctgcc tcagcttccc gagtagctgg gattacagat gtgagccacc     3960

gtacccagct aatttttgta tttttagtag agacggggtt tcaccatatt ggccaagctg     4020

gtctcgaact cctgacctca ggcgatccat ctgtctcagc ctcccaaagt gctgggatta     4080

caggtgtgag ccaccgcgcc aggcctcagc ccacttcttt tgggtggcaa tggtttggat     4140

atcgtttgtc ctcactaaaa ttcatgttga gattcgagcc ccagtgtggc aggtgttggg     4200

atgtggggcc tcataaggag ctgtgtggtc ttggaggtgg agtcctcatg gatagattaa     4260

tgcctgcctt aaggggtgag tgagtgctca cccttgggaa tttgggaatt tggttttctc     4320

tcccttgctt ccttcagcac catgtgatct ctgtgcacac agctgcatcc ttctgccctc     4380

ccccagaagc agcagcagcc tcagggatga gggaggtcct cagtgagtgc acctgcccag     4440

tcttgaacct tccagccatc agaatctgag ccaaatcaac ctcttccttt ataaagaccc     4500

agcctcaggt cttctgtcag agcaacacaa aatggactca gcacggatca aattgtgtct     4560

cccccacccc cacaaaaaac tttatattaa aatcctaacc cccagcaaaa aaaaaaaaaa     4620

aaaaa                                                                 4625


<210>  2383
<211>  564
<212>  DNA
<213>  homo sapiens

<400>  2383
attcttcccc tctctacaac cctctctcct cagcgcttct tctttcttgg tttggtgctt       60

ctgagatgtg ggcttgcaca cgctgttgct atagtacgtg ttgatcctga ctgctgtcat      120

ggcgtgccct ctggagaagg ccctggatgt gatggtgtcc accttccaca agtactcggg      180

caaagagggt gacaagttca agctcaacaa gtcagaacta aaggagctgc tgacccggga      240

gctgcccagc ttcttgggga aaaggacaga tgaagctgct ttccagaagc tgatgagcaa      300

cttggacagc aacagggaca acgaggtgga cttccaagag tactgtgtct tcctgtcctg      360

catcgccatg atgtgtaacg aattctttga aggcttccca gataagcagc ccaggaagaa      420

atgaaaactc ctctgatgtg gttggggggt ctgccagctg gggccctccc tgtcgccagt      480

gggcactttt ttttttccac cctggctcct tcagacacgt gcttgatgct gagcaagttc      540

aataaagatt cttggaagtt ttga                                             564


<210>  2384
<211>  3096
<212>  DNA
<213>  homo sapiens

<400>  2384
attctttctt cgtgttcctg tgcgggattg gtgtgcccag gggtttggct ttccaattgg       60

ctaacgccgg ggtgggtggg gaatgtgggg agatttgaat ttgaaaccgg tagggagtga      120

taatccgcat tcagttgtcg aggagtgcca gtcaccttca gtttctggag ctggccgtca      180

acatgtcctt tcctaaggcg cccttgaaac gattcaatga cccttctggt tgtgcaccat      240

ctccaggtgc ttatgatgtt aaaactttag aagtattgaa aggaccagta tcctttcaga      300

aatcacaaag atttaaacaa caaaaagaat ctaaacaaaa tcttaatgtt gacaaagata      360

ctaccttgcc tgcttcagct agaaaagtta agtcttcgga atcaaagatt cgtgttcttc      420

tacaggaacg tggtgcccag gacaggcgga tccaggatct ggaaactgag ttggaaaaga      480

tggaagcaag gctaaatgct gcactaaggg aaaaaacatc tctctctgca aataatgcta      540

cactggaaaa acaacttatt gaattgacca ggactaatga actactaaaa tctaagtttt      600

ctgaaaatgg taaccagaag aatttgagaa ttctaagctt ggagttgatg aaacttagaa      660

acaaaagaga aacaaagatg aggggtatga tggctaagca agaaggcatg gagatgaagc      720

tgcaggtcac ccaaaggagt ctcgaagagt ctcaagggaa aatagcccaa ctggagggaa      780

aacttgtttc aatagagaaa gaaaagattg atgaaaaatc tgaaacagaa aaactcttgg      840

aatacatcga agaaattagt tgtgcttcag atcaagtgga aaaatacaag ctagatattg      900

cccagttaga agaaaatttg aaagagaaga atgatgaaat tttaagcctt aagcagtctc      960

ttgaggagaa tattgttata ttatctaaac aagtagaaga tctaaatgtg aaatgtcagc     1020

tgcttgaaaa agaaaaagaa gaccatgtca acaggaatag agaacacaac gaaaatctaa     1080

atgcagagat gcaaaactta aaacagaagt ttattcttga acaacaggaa cgtgaaaagc     1140

ttcaacaaaa agaattacaa attgattcac ttctgcaaca agagaaagaa ttatcttcga     1200

gtcttcatca gaagctctgt tcttttcaag aggaaatggt taaagagaag aatctgtttg     1260

aggaagaatt aaagcaaaca ctggatgagc ttgataaatt acagcaaaag gaggaacaag     1320

ctgaaaggct ggtcaagcaa ttggaagagg aagcaaaatc tagagctgaa gaattaaaac     1380

tcctagaaga aaagctgaaa gggaaggagg ctgaactgga gaaaagtagt gctgctcata     1440

cccaggccac cctgcttttg caggaaaagt atgacagtat ggtgcaaagc cttgaagatg     1500

ttactgctca atttgaaagc tataaagcgt taacagccag tgagatagaa gatcttaagc     1560

tggagaactc atcattacag gaaaaagcgg ccaaggctgg gaaaaatgca gaggatgttc     1620

agcatcagat tttggcaact gagagctcaa atcaagaata tgtaaggatg cttctagatc     1680

tgcagaccaa gtcagcacta aaggaaacag aaattaaaga aatcacagtt tcttttcttc     1740

aaaaaataac tgatttgcag aaccaactca agcaacagga ggaagacttt agaaaacagc     1800

tggaagatga agaaggaaga aaagctgaaa aagaaaatac aacagcagaa ttaactgaag     1860

aaattaacaa gtggcgtctc ctctatgaag aactatataa taaaacaaaa ccttttcagc     1920

tacaactaga tgcttttgaa gtagaaaaac aggcattgtt gaatgaacat ggtgcagctc     1980

aggaacagct aaataaaata agagattcat atgctaaatt attgggtcat cagaatttga     2040

aacaaaaaat caagcatgtt gtgaagttga aagatgaaaa tagccaactc aaatcggaag     2100

tatcaaaact ccgctgtcag cttgctaaaa aaaaacaaag tgagacaaaa cttcaagagg     2160

aattgaataa agttctaggt atcaaacact ttgatccttc aaaggctttt catcatgaaa     2220

gtaaagaaaa ttttgccctg aagaccccat taaaagaagg caatacaaac tgttaccgag     2280

ctcctatgga gtgtcaagaa tcatggaagt aaacatctga gaaacctgtt gaagattatt     2340

tcattcgtct tgttgttatt gatgttgctg ttattatatt tgacatgggt attttataat     2400

gttgtattta attttaactg ccaatcctta aatatgtgaa aggaacattt tttaccaaag     2460

tgtcttttga cattttattt tttcttgcaa atacctcctc cctaatgctc acctttatca     2520

cctcattctg aaccctttcg ctggctttcc agcttagaat gcatctcatc aacttaaaag     2580

tcagtatcat attattatcc tcctgttctg aaaccttagt ttcaagagtc taaaccccag     2640

attcttcagc ttgatcctgg aggtcttttc tagtctgagc ttctttagct aggctaaaac     2700

accttggctt gttattgcct ctactttgat tctgataatg ctcacttggt cctacctatt     2760

atccttctac ttgtccagtt caaataagaa ataaggacaa gcctaacttc atagaaacct     2820

ctctattttt aatcagttgt ttaataattt acaggttctt aggctccatc ctgtttgtat     2880

gaaattataa tctgtggatt ggcctttaag cctgcattct taacaaactc ttcagttaat     2940

tcttagatac actaaaaatc tgagaaactc tacatgtaac tatttcttca gagtttgtca     3000

tatactgctt gtcatctgca tgtctactca gcatttgatt aacatttgtg taatatgaaa     3060

taaaattaca cagtaagtca tttaaccaat taaaaa                               3096


<210>  2385
<211>  2473
<212>  DNA
<213>  homo sapiens

<400>  2385
acagatggtg tgggagcgcg ttccccggta ggagggggcg cgagcgagca agcaggcagg       60

cagctgccag gagctcttcc ctgctcgctc acgcctgctc tcagaagctc cgatccagac      120

acacgcgagg cgctgtcctt tcagcaccac aagctcgggc tgaggaggga ggactcctgg      180

ccgtcctcct cctcttcaaa ttggcttgaa tctgctctga ccccccacga gtgcagcaca      240

gtctgggaag aaaggcgtaa ggatggtgaa gctgaacagt aaccccagcg agaagggaac      300

caagccgcct tcagttgagg atggcttcca gaccgtccct ctcatcactc ccttggaggt      360

taatcactta cagctgcctg ctccagaaaa ggtgattgtg aagacaagaa cggaatatca      420

gccggaacag aagaacaaag ggaagttccg ggtgccgaaa atcgctgaat ttacggtcac      480

catccttgtc agcctggccc tagctttcct tgcgtgcatc gtgttcctgg tggtttacaa      540

agccttcacc tatgatcaca gctgcccaga gggattcgtc tataagcaca aacgctgtat      600

cccagcctcc ctggatgctt actactcctc ccaggacccc aattccagaa gccgcttcta      660

cacagtcatc agccactaca gcgtggccaa gcagagcact gcccgggcca tcgggccgtg      720

gctgtcagca gccgctgtca tccatgagcc caagccgccc aagacccagg gccactagag      780

gcctgcccca gccagaatgg ggggcggggt ggagaggagg acccccattg gctaagccaa      840

gctccagtta caagacaaca ctgtactcct gggatatggg ggcgggggcg gggcagggca      900

gggtgggggg aagaacgcac caaaaacgtg gtgtgtgctg gagttgtctg aaccgatatt      960

tctttttgtt ccttggtatt gttgattcgt cgccgagtca ggctcatgta caaaggcatg     1020

tttcgtgttg attgttccca tgtaagatat ttttaaagcc actgcttatt ctttgttagg     1080

aaaatgtaac agcagaaaag gaaagaaaca aagaacatga acaaaaagca ttaaactggc     1140

tccatcagaa gacgttgaag ggcagtgaag agcacagact ctgtgggctt cttagataag     1200

aaaacgtagc ttcagtgggg gctccagggt tgcagagtat gagtgacaca gaccgggact     1260

attccattag cctgtggtct gcagggtagg cccgcaggaa atgaggaatg gccgagctgg     1320

agagaagagc tgattttggc attactaagc ccagaacgca cataacccat agtgaaatgt     1380

gctggcctct ggtgcatttt gcaagatgag cacaaacttt ctgggcctcc atcctaggac     1440

ctgggcagac ccacatggcc tgggctctga atgcccaccc tgcgacggtg ggttctgcat     1500

cagcaaacgc tgaggagtgg gcagattttc tttgtctttt gcttgcattt tctagatcca     1560

cacctggata ctgcccatgt tgacgagaca gcagcagggg gagagggagg gaaggaaggt     1620

gcggctgcaa gaaggaaggc acgggacagg catgtgacac taggccacaa gcgataagca     1680

caggcacctg acttttaagt ttttgtttgt ttgttgtttc ccaaagtgct gataacaata     1740

acaacaacaa taggattcca accaggagcc tcaagtgaca gccaggaaga gacctgaagg     1800

ttggggccac cacaatgcca aatcgtttct aaaggaagct gaaaaatggg actgtctttt     1860

gcccacttcg ttgtgttaaa aggggacatt tgtccaaact ccccaaccga gttctagaag     1920

ctcctgacaa ggaggcagca tccagccttg accaggcctc ccagttccct ggaaccgtat     1980

caggcattcg cctgcctctc acaaatgttt cagggaggcc agttctgcag ggtgtcagct     2040

ccaggaccca cagggccaga accagctggg agaattggtt atttgagatg tggtactgct     2100

tcctcacaag tctcccacag gccatgtaaa gggtattttt ttgtggcttg ctgtgttgct     2160

gagatcatcg tatgcaacag ctgggtaata agactagcat agctcaaact atcctgccaa     2220

acgctctcat ctgatttttc ctcccttctc ccccaacctc caatcaccct gagtcacctg     2280

taaattcatt tgtcattcaa agcggaataa caagttgtcc ctagcaaaac cgctgagcgc     2340

tttataattt tgtggtgtat ttttgtcagt aggtagcaga ggcggaagta ttttttggtg     2400

taattcttga aattttctga caggaaacaa ataaagatag atgtgtctga gaaaaaaaaa     2460

aaaaaaaaaa aaa                                                        2473


<210>  2386
<211>  2834
<212>  DNA
<213>  homo sapiens

<400>  2386
gaacgcaagt cccgcttcgc tctcgggggc ggactcagcg gcggaagtgg cgctgccgga       60

agatcttctt ccgctctgag gcgctactga ggccgcggag ccggactgcg gttggggcgg      120

gaagagccgg ggccgtggct gacatggagc agccctgctg ctgaggccgc gccctccccg      180

ccctgaggtg ggggcccacc aggatgagca agctgcccag ggagctgacc cgagacttgg      240

agcgcagcct gcctgccgtg gcctccctgg gctcctcact gtcccacagc cagagcctct      300

cctcgcacct ccttccgccg cctgagaagc gaagggccat ctctgatgtc cgccgcacct      360

tctgtctctt cgtcaccttc gacctgctct tcatctccct gctctggatc atcgaactga      420

ataccaacac aggcatccgt aagaacttgg agcaggagat catccagtac aactttaaaa      480

cttccttctt cgacatcttt gtcctggcct tcttccgctt ctctggactg ctcctaggct      540

atgccgtgct gcggctccgg cactggtcac gacgctggtg tccagtgcat tcctcattgt      600

caaggtcatc ctctctgagc tgctcagcaa aggggcattt ggctacctgc tccccatcgt      660

ctcttttgtc ctcgcctggt tggagacctg gttccttgac ttcaaagtcc taccccagga      720

agctgaagag gagcgattct gctcctccag ggtatcttgc cgcccaggtt gctgttgccc      780

gtggacccct gctgttctcc ggtgctctgt ccgagggaca gttctattca cccccagaat      840

cctttgcagg gtctgacaat gaatcagatg aagaagttgc tgggaagaaa agtttctctg      900

ctcaggagcg ggagtacatc cgccagggga aggaggccac ggcagtggtg gaccagatct      960

tggcccagga agagaactgg aagtttgaga agaataatga atatggggac accgtgtaca     1020

ccattgaagt tccctttcac ggcaagacgt ttatcctgaa gaccttcctg ccctgtcctg     1080

cggagctcgt gtaccaggag gtgatcctgc agcccgagag gatggtgctg tggaacaaga     1140

cagtgactgc ctgccagatc ctgcagcgag tggaagacaa caccctcatc tcctatgacg     1200

tgtctgcagg ggctgcgggc ggcgtggtct ccccaaggga cttcgtgaat gtccggcgca     1260

ttgagcggcg cagggaccga tacttgtcat cagggatcgc cacctcacac agtgccaagc     1320

ccccgacgca caaatatgtc cggggagaga atggccctgg gggcttcatc gtgctcaagt     1380

cggccagtaa cccccgtgtt tgcacctttg tctggattct taatacagat ctcaagggcc     1440

gcctgccccg gtacctcatc caccagagcc tcgcggccac catgtttgaa tttgcctttc     1500

acctgcgaca gcgcatcagc gagctggggg cccgggcgtg actgtgcccc ctcccaccct     1560

gcgggccagg gtcctgtcgc caccacttcc agagccagaa agggtgccag ttgggctcgc     1620

actgcccaca tgggacctgg ccccaggctg tcaccctcca ccgagccacg cagtgcctgg     1680

agttgactga ctgagcaggc tgtggggtgg agcactggac tccggggccc cactggctgg     1740

aggaagtggg gtctggcctg ttgatgttta catggcgccc tgcctcctgg aggaccagat     1800

tgctctgccc caccttgcca gggcagggtc tgggctgggc acctgacttg gctggggagg     1860

accagggccc tgggcagggc agggcagcct gtcacccgtg tgaagatgaa ggggctcttc     1920

atctgcctgc gctctcgtcg gtttttttag gattattgaa agagtctggg acccttgttg     1980

gggagtgggt ggcaggtggg ggtgggctgc tggccatgaa tctctgcctc tcccaggctg     2040

tccccctcct cccagggcct cctgggggac ctttgtatta agccaattaa aaacatgaat     2100

ttaaaaaaaa aaaaaaattc cagcccctcc cactgccttg cctcttgagg gaagagaaag     2160

gcaggcagca gcttggatga agagggaaga cccctcacac agcctctcct gggctcacag     2220

gagggcggag cccggggagc cagttcctga aacatgcccc ccattccccc cccgcccacc     2280

ccccactccc cgctttcctg accagttcaa ctgagcagat gactggtcag aaaaaaatgc     2340

cccgccccct gccaggcttc agcggggcaa gtttaaagtc tctagtccag gaatggaggt     2400

gggggtatgg gcacctggca gtgcccacag caagccttga ctgtgtggcc tggagatggg     2460

gcctgagctt cagggtcact gaggcacctc tgggatccag gccacctgga gccccggacc     2520

tcccagactc cactcaccca ttccctctcc ccgcacggca ctcacaccag gggcggcctg     2580

gagcccggat cgcagggcgg ggccaggcca ctgcctgcct tcctcctccc tcccggctgg     2640

cctgccccct tgcctgcctg catgcaggct tccagcagag ccagcttctt cagagccagg     2700

tggatcctgt ttcggtcctg cctaggtgtg tgaccctggg cgaatctacc tctctcagct     2760

tctgcttccc actttatgaa aatgggactg atgtcacagg gttgttatga gattaaaaga     2820

tatgaagaac cggg                                                       2834


<210>  2387
<211>  942
<212>  DNA
<213>  homo sapiens

<400>  2387
ggcggcgtgt ttgaaagcga ggccaaagtg ggtgggagcg cgtgctgttg ggagttgctt       60

ggaggttggc ggcgcggggc tgaaggctag caaaccgagc gatcatgtcg cacaaacaaa      120

tttactattc ggacaaatac gacgacgagg agtttgagta tcggttagtg ctggcgcggg      180

agcaatagcg agggtcgtga gctttggccg ctgagggcac aaggaattag taacaggaac      240

tgaggcgata gaattggcgc atgcgtacga gacatgtcat gctgcccaag gacatagcca      300

agctggtccc taaaacccat ctgatgtctg aatctgaatg gaggaatctt ggcgttcagc      360

agagtcaggg atgggtccat tatatgatcc atgaaccaga acctcacatc ttgctgttcc      420

ggcgcccact acccaagaaa ccaaagaaat gaagctggca agctactttt cagcctcaag      480

ctttacacag ctgtccttac ttcctaacat ctttctgata acattattat gttgccttct      540

tgtttctcac tttgatattt aaaagatgtt caatacactg tttgaatgtg ctggtaactg      600

ctttgcttct tgagtagagc caccaccacc atagcccagc cagatgagtg ctctgtggac      660

ccacagccta agctgagtgt gaccccagaa gccacgatgt gctctgtatc cagaacacac      720

ttggcagatg gaggaagcat ctgagtttga gaccatggct gttacaggga tcatgtaaac      780

ttgctgtttt tgttttttcc tgccgggtgt tgtatgtgtg gtgacttgcg gatttatgtt      840

tcagtgtact ggaaactttc cattttattc aagaaatctg ttcatgttaa aagccttgat      900

taaagaggaa gtttttataa tctaaaaaaa aaaaaaaaaa aa                         942


<210>  2388
<211>  3422
<212>  DNA
<213>  homo sapiens

<400>  2388
gacgcagggt cggcggctca gcgccgtaga gacaaagccg cccgcccgcc agcccgctag       60

ctcctcgcgc gagctcctcc tccacgggaa cctccctccc ctcccaggcg ccgccgcagc      120

cggagcggct cccgggccct gggccgccgc cggccaggaa gaaatacttg tgttggctgc      180

atttccaggg atgctaccag agctcaaggc tgtcacctgg tcttgcccag aagagccgtt      240

cttagaggca ggacttgatg aaggctttcc tgctgatgga ataggtttgc tagagctggc      300

cttggaatta gaacccttca tgtggccttt ataaatatgc gtttgagaca gagttatatg      360

cagaagttga aaatgcctgg aagatttctg gtttctttca ctacttatcc tgcctttttg      420

catcgctgcc agatttggat gatatgatat tcagaggggc accttaatca aagccattct      480

tcaacaagac ccacctggca taagattgca cacataattc aagatggcca gtcaacctcc      540

tgaagacact gcggagtctc aggcctctga tgagctggag tgcaaaatct gttacaatcg      600

atacaatctg aaacagagga aacccaaagt gctggagtgt tgtcataggg tttgtgccaa      660

atgcctctac aagatcatag actttgggga ctccccacaa ggtgtcattg tctgtccttt      720

ctgcaggttt gagacgtgcc tgccagatga tgaagttagt agcctgcccg atgacaacaa      780

catccttgta aacttgactt gtggaggcaa agggaagaag tgcctgccag agaaccctac      840

tgagctgctg ctcaccccca agaggctggc ctctctggtc agtccttctc acacgtcctc      900

caactgcctg gtcataacca tcatggaggt gcagagagag agctccccgt ccctgagctc      960

cactcctgtg gtagaatttt ataggcctgc gagtttcgac tctgtcacca ctgtgtcaca     1020

caactggact gtgtggaact gcacgtccct gctgtttcag acatccatcc gggtgttagt     1080

gtggttgcta ggtttgctct acttcagctc cttaccctta ggaatctact tactggtgtc     1140

taagaaagtc acccttgggg tcgtctttgt cagcctggtc ccttcgagcc tcgttattct     1200

tatggtgtat ggtttttgcc agtgtgtttg tcatgaattt ctagactgta tggcacctcc     1260

ttcttaactg atatgcaaaa taagaaattg gacacacatt gccctgtttg agtgtgaagt     1320

tagataattt ataatttatt ttcttttatg ttctttatga ttagtatcca tgacattaac     1380

aaaacccttg gccacatgtt gacttgattg gttttcctgt aggctggaag taaaaatgtt     1440

catttctact taggggttag caaaattgta taagctcaca cttcatggag cactgacagc     1500

agtgagtctt cccagagaaa ggacagggtt tctctcagca ctgccagaca gacggcaggg     1560

gtgtggtgtg ttatactata gggagagcat ggatccctcc tttcgtattc atggatgttc     1620

tatgatggca gttggacaca agaggaaagt tgctctgaga cacaaagtgt gtactccttt     1680

cccaccccat acccctggta ttggaacacc ctagaattgt cttcaggtgt tttctctctt     1740

aagtcactct ctgtggtcgg cgatcccatt gagatacttg tttcctctgc ccattctccc     1800

ttgccaagag gaaactcggt tccattccct tgggtagttt caactgaata ccagttttgc     1860

cacattacta aggagaatga aaagcactga ggaatttgca tcacagtcag cttcatggca     1920

gaatgtggcc atttgtcctt gagacacact ctttcctcca tgtctgtttt cctctctcct     1980

cagtcttatc tgagaagaat ggaggagaag gaacttctca tacagcggtt attattgatg     2040

aaaaccttca tttgagtctt tccttataac atcttagttt tggttttttt aaaccacatt     2100

gcccaatcag cctcacccct tgtcctgaaa aggttccatt taaattagtt gctataaatt     2160

catcaatact ttttttccct attatatttt tggttctatt aggatttact taactgaatc     2220

ttataacaat tcgaggtgaa ctgtggcaat gaaaaccaga aacagttaat gagatgcttc     2280

agctcacagt ttgaagtgct gagaacctaa gtattttgct gtacggtact gagctgtacc     2340

aaaatatgat ggtttaggtt tatgtgcaag actttgtgtt gtagtctaga caaaggggtg     2400

ggcaagagac atgcaaagct gaagccctgc ttgaaaagac ccttcaagga agtaaaatgg     2460

caggggcaga gtgcagctta acatgttgct atccctgttg tttttgagtt ggttttggaa     2520

tggattcaag ttcttacaca atttattttg aatacaagca taatctaggt gatttgagtt     2580

aatgaacttc ttttcatgat gtagggaaag ttgaatgtat atatttctaa gaagaatttg     2640

tttagcagat tacaagttgg caaaatagac tgttcacaga aactaggcaa aaatttaaaa     2700

aaacattcta gtctctaaaa cccattacta atgattaaca ttaaaatatt tgtaactctt     2760

agaaaggggg cattactaag acgactttaa cttgttatga aatctttgtt gtgtgatgca     2820

ggtacagtgc gcccattcca actggaatag cagtttgatt ttaattgtaa aactaaactt     2880

cgggaatatg tatgcccaaa gtaagtagga tgagaatagt atacatggga tatggtccaa     2940

tgaatttaag ccccaagata cagctaaata catttatgat ttcataaaat ctagtttaga     3000

tagcattgtg atgcaatttc cagaaatcca tttgtgttta gagtaaatac catgtttaga     3060

agatgttttg tggtttggat ttatatattt gtaaggtttt tttaaaaaaa tgttcgtttt     3120

gtttgaaatg taacattgag taaattggtg agttatataa tgagatttct agaaagctct     3180

ggacatgggt acgatgtgtt ttgcttctct gtataatgtc tacagtgata aacttgtgtc     3240

tccgtgtatt gtggcagtct ttttttctag ttaatttggc tttagagagc aatctttgta     3300

tgacaccaga aaactcttca tgctattgaa tgataaaaag ataatgcttt aatattttat     3360

tcactgtgat actattttgt ttgtctatta aattgttatt atttccaaat ttaaaaaaaa     3420

aa                                                                    3422


<210>  2389
<211>  2812
<212>  DNA
<213>  homo sapiens

<400>  2389
agctgggctt tgtggagcgc tgcggagggt gcgtgcgggc cgcggcagcc gaacaaagga       60

gcaggggcgc cgccgcaggg acccgccacc cacctcccgg ggccgcgcag cggcctctcg      120

tctactgcca ccatgaccgc caacggcaca gccgaggcgg tgcagatcca gttcggcctc      180

atcaactgcg gcaacaagta cctgacggcc gaggcgttcg ggttcaaggt gaacgcgtcc      240

gccagcagcc tgaagaagaa gcagatctgg acgctggagc agccccctga cgaggcgggc      300

agcgcggccg tgtgcctgcg cagccacctg ggccgctacc tggcggcgga caaggacggc      360

aacgtgacct gcgagcgcga ggtgcccggt cccgactgcc gtttcctcat cgtggcgcac      420

gacgacggtc gctggtcgct gcagtccgag gcgcaccggc gctacttcgg cggcaccgag      480

gaccgcctgt cctgcttcgc gcagacggtg tcccccgccg agaagtggag cgtgcacatc      540

gccatgcacc ctcaggtcaa catctacagc gtcacccgta agcgctacgc gcacctgagc      600

gcgcggccgg ccgacgagat cgccgtggac cgcgacgtgc cctggggcgt cgactcgctc      660

atcaccctcg ccttccagga ccagcgctac agcgtgcaga ccgccgacca ccgcttcctg      720

cgccacgacg ggcgcctggt ggcgcgcccc gagccggcca ctggctacac gctggagttc      780

cgctccggca aggtggcctt ccgcgactgc gagggccgtt acctggcgcc gtcggggccc      840

agcggcacgc tcaaggcggg caaggccacc aaggtgggca aggacgagct ctttgctctg      900

gagcagagct gcgcccaggt cgtgctgcag gcggccaacg agaggaacgt gtccacgcgc      960

cagggtatgg acctgtctgc caatcaggac gaggagaccg accaggagac cttccagctg     1020

gagatcgacc gcgacaccaa aaagtgtgcc ttccgtaccc acacgggcaa gtactggacg     1080

ctgacggcca ccgggggcgt gcagtccacc gcctccagca agaatgccag ctgctacttt     1140

gacatcgagt ggcgtgaccg gcgcatcaca ctgagggcgt ccaatggcaa gtttgtgacc     1200

tccaagaaga atgggcagct ggccgcctcg gtggagacag caggggactc agagctcttc     1260

ctcatgaagc tcatcaaccg ccccatcatc gtgttccgcg gggagcatgg cttcatcggc     1320

tgccgcaagg tcacgggcac cctggacgcc aaccgctcca gctatgacgt cttccagctg     1380

gagttcaacg atggcgccta caacatcaaa gactccacag gcaaatactg gacggtgggc     1440

agtgactccg cggtcaccag cagcggcgac actcctgtgg acttcttctt cgagttctgc     1500

gactataaca aggtggccat caaggtgggc gggcgctacc tgaagggcga ccacgcaggc     1560

gtcctgaagg cctcggcgga aaccgtggac cccgcctcgc tctgggagta ctagggccgg     1620

cccgtccttc cccgcccctg cccacatggc ggctcctgcc aaccctccct gctaacccct     1680

tctccgccag gtgggctcca gggcgggagg caagccccct tgcctttcaa actggaaacc     1740

ccagagaaaa cggtgccccc acctgtcgcc cctatggact ccccactctc ccctccgccc     1800

gggttcccta ctcccctcgg gtcagcggct gcggcctggc cctgggaggg atttcagatg     1860

cccctgccct cttgtctgcc acggggcgag tctggcacct ctttcttctg acctcagacg     1920

gctctgagcc ttatttctct ggaagcggct aagggacggt tgggggctgg gagccctggg     1980

cgtgtagtgt aactggaatc ttttgcctct cccagccacc tcctcccagc cccccaggag     2040

agctgggcac atgtcccaag cctgtcagtg gccctccctg gtgcactgtc cccgaaaccc     2100

ctgcttggga agggaagctg tcgggtgggc taggactgac ccttgtggtg tttttttggg     2160

tggtggctgg aaacagcccc tctcccacgt ggcagaggct cagcctggct cccttccctg     2220

gagcggcagg gcgtgacggc cacagggtct gcccgctgca cgttctgcca aggtggtggt     2280

ggcgggcggg taggggtgtg ggggccgtct tcctcctgtc tctttccttt caccctagcc     2340

tgactggaag cagaaaatga ccaaatcagt atttttttta atgaaatatt attgctggag     2400

gcgtcccagg caagcctggc tgtagtagcg agtgatctgg cggggggcgt ctcagcaccc     2460

tccccagggg gtgcatctca gccccctctt tccgtccttc ccgtccagcc ccagccctgg     2520

gcctgggctg ccgacacctg ggccagagcc cctgctgtga ttggtgctcc ctgggcctcc     2580

cgggtggatg aagccaggcg tcgccccctc cgggagccct ggggtgagcc gccggggccc     2640

ccctgctgcc agcctccccc gtccccaaca tgcatctcac tctgggtgtc ttggtctttt     2700

attttttgta agtgtcattt gtataactct aaacgcccat gatagtagct tcaaactgga     2760

aatagcgaaa taaaataact cagtctgcag ccccagaaaa aaaaaaaaaa aa             2812


<210>  2390
<211>  6344
<212>  DNA
<213>  homo sapiens

<400>  2390
atgcattaaa ctccaggtat tttcagggag gaatcatgaa gccgctcctg ttaaatcata       60

tccattttat tacgtctctc cttgtggatt acgtagaact ttggaaaatt aaacattaga      120

catcttcata gaaaatcatg tcactgattt ttaaagccag ctcaatttaa cctgccactg      180

attccctaac cagctcttct ctgactgtat cccgagggaa aatgtattga acgcagcaga      240

aggttaaggc agaggagttc ggctagaccg ggtagcagcc aatcagatgg ggagggtcca      300

aggatctgat gcctccaggc gagcagcgcc aagctgagct ggttagtctc cttttattgt      360

ggatgaacac cacgtacatg ccgtaaatgc tccctaggct ggctgcggct acaaggcaga      420

cccgggagct gagaatagag gaatacctgc ccaagcaact cattctgcac agcagccgac      480

aagacagcga ttttcctgtg ctggaatgtg cccatccaaa gacacttgga ttggacttaa      540

tcttaaacct ctggagttca agacctttta aaaagggcta aataaacaat ctctacatgt      600

aaaaggccac tgactcctac ttcctctgta tagagcaact gttgaactca gctgcctgta      660

gggcgtgatt ctcagtcacc agactcagct tggagatctt acaatgatgg caatcaggag      720

acactgaacg gagatgctac atattcctct cttgcagcaa aaggttttag aagcgttcga      780

ccaaacctac aagataaaag atcaccaact cagagccaga taacagtgaa tggaaactca      840

ggaggtgccg tgagtcccat gagttactat cagaggccgt tttccccctc ggcatattct      900

ctcccagcct cactcaactc cagcattgtc atgcagcacg gcacatccct cgattccaca      960

gacacatatc cccagcatgc gcagtctctg gatggcacca ccagcagctc tatccccctg     1020

taccgatcct cagaggaaga gaagagagtg acagtcatca aagccccgca ttacccaggg     1080

atcgggcccg tggatgaatc cggaatcccc acagcaatta gaacgacagt cgaccggccc     1140

aaggactggt acaagacgat gtttaagcaa attcacatgg tgcacaagcc ggatgatgac     1200

acagacatgt ataatactcc ttatacatac aatgcaggtc tgtacaaccc accctacagt     1260

gctcagtcac accctgctgc aaagacccaa acctacagac ctctttccaa aagccactcc     1320

gacaacagcc ccaatgcctt taaggatgcg tcctccccag tgcctccccc acatgttcca     1380

cctccagtcc cgccgcttcg accaagagat cggtcttcaa cagaaaagca tgactgggat     1440

cctccagaca gaaaagtgga cacaagaaaa tttcggtctg agccaaggag tatttttgaa     1500

tatgaacctg gcaagtcatc aattcttcag catgaaagac cagcctcctt gtatcagtcc     1560

tctatagaca gaagcctgga aagacccatg agttctgcaa gcatggccag tgacttcagg     1620

aagcggagga agagcgagcc tgcagtgggt ccaccacggg gcttgggaga tcaaagtgcg     1680

agcaggacta gcccaggccg agtggacctc ccaggatcaa gcaccactct tacaaagtct     1740

ttcactagct cttctccttc ttccccatca agagcaaaag gtggggatga tagcaaaata     1800

tgtccatccc tttgcagtta ctcagggctc aacggcaacc cctccagtga gttagattac     1860

tgtagcactt acagacagca cttggatgtc cctcgggact caccaagagc cattagtttc     1920

aagaacggct ggcaaatggc ccggcaaaac gcagaaatct ggagcagcac ggaagaaacc     1980

gtctctccca aaatcaaatc ccggagctgt gacgatctcc taaacgacga ctgcgatagc     2040

ttcccggacc cgaaagtcaa gtcggaaagc atgggctccc tgttatgtga ggaggactcc     2100

aaggagagct gccccatggc gtgggggtcc ccctacgtcc cggaggttcg cagtaacggc     2160

agatcaagga tcagacacag gtcagcccgc aacgccccgg ggttcctgaa gatgtacaag     2220

aaaatgcacc gcatcaaccg caaggacctg atgaactccg aggtgatctg ctccgtgaag     2280

tccaggattc tgcagtacga gagcgagcag cagcacaagg acctgctgcg cgcctggagc     2340

cagtgctcca cggaggaggt gccccgggac atggtgccca cacgcatctc cgaattcgaa     2400

aagctgatcc agaagtccaa atccatgcca aatttagggg atgacatgct gtctcccgta     2460

accctagaac caccgcaaaa tggcctatgt cccaagaggc ggttttccat tgagtatttg     2520

ctggaggaag aaaatcaaag cggccccccc gctcggggcc ggcgaggctg ccagtctaac     2580

gccctggtgc ccattcacat tgaagtcacc agcgatgagc agccccgagc acacgtggag     2640

ttttccgaca gcgaccagga cggggttgtg tccgaccaca gtgactacat tcacctagag     2700

gggtcatcct tctgcagtga aagtgacttt gatcactttt ccttcacatc ctccgaaagc     2760

ttttacggat ccagccacca ccaccaccat caccaccacc accaccaccg ccacctcatc     2820

agctcctgca aaggcaggtg cccggcctcc tacactcgat ttaccacaat gttaaaacac     2880

gaaagagcca gacacgaaaa caccgaggag cccagaaggc aagaaatgga ccctggcctt     2940

tctaaacttg cttttctagt cagtcctgtg cctttccgga ggaaaaaaaa ttcggctcct     3000

aagaaacaga ctgaaaaggc aaaatgtaaa gcatctgtgt ttgaggctct ggactctgcc     3060

cttaaagaca tctgtgacca aattaaagct gaaaagaaaa gggggagctt gccggacaac     3120

agcatcctgc accgcctcat cagtgagctg ctgccagatg ttcccgagag gaactcatcc     3180

ctgagagcgc tgaggaggag ccccctgcac cagcctctcc acccactgcc tcccgatggt     3240

gctattcatt gtccacccta ccagaatgac tgcgggagaa tgccccgcag tgcctctttc     3300

caagacgtgg acacagccaa cagcagctgc caccaccaag accgtggcgg tgcactccaa     3360

gaccgtgagt cccctagaag ttactcatcc actttgactg acatggggag aagtgcacca     3420

agggaaagaa gaggaactcc agaaaaagag aaattgcctg caaaagctgt ttatgatttt     3480

aaggctcaga catctaagga gttgtcattt aagaaaggag atactgtcta catcctcagg     3540

aaaattgatc aaaattggta tgagggagaa caccacggga gagtgggcat cttcccgatc     3600

tcatacgtag agaaactcac acctcctgag aaagcacagc ctgcaagacc acctccgcca     3660

gcccagcccg gagaaatcgg agaagctata gccaaataca acttcaacgc agacacaaat     3720

gtggagctgt cactgagaaa gggagataga gttattcttc ttaaaagagt tgatcaaaac     3780

tggtatgaag gtaaaatccc aggaaccaac agacaaggca tcttccctgt ttcctatgtg     3840

gaggtcgtca agaagaacac aaaaggtgct gaggactacc ctgaccctcc aataccccac     3900

agctattcta gtgataggat tcacagcttg agctcaaata agccacagcg tcctgtgttt     3960

actcatgaaa atattcaagg tgggggggaa ccgtttcagg ctctgtataa ctatactccc     4020

aggaatgaag atgagctgga gctcagagaa agtgatgtca ttgatgtcat ggaaaagtgt     4080

gatgacggct ggtttgtggg gacctcaaga agaaccaaat tctttggtac tttccccgga     4140

aactacgtca agaggctgtg aattgcgctc cctccttctg tagaggccgc ctgccagcca     4200

tgcacctgcg tcaacgcgcc tgaaacaccc cgcgggcctc ccgttgtcat gccttacggt     4260

ttccaatgcg ccgtcaccat ctccacctgc caccaaacca ccagcagagt agccgccgct     4320

gctgtgagcc tggggacgac atggcaggct ggtccccctc cgtgaaagtg tggattccta     4380

cttcctgctc taagctttga cacgtcaaaa tgtgggatca gaaagaaaaa aatcatgata     4440

tttaaaaatg gtcaaatatt tgaggcaaaa aaaaaaaaaa aaagtgtctc caggaggctg     4500

tccagcctcg tggctccatt tcaacatctc cccccaggcg atgttctccc ccaagacgac     4560

cagaaaattg tttattgggg aatgctgtgg tttgcatttt catattcttc gcttggcagt     4620

gtgtattctt ttcacaagtt tgcctagtgt cttggtttac acaatatgac aactgtaact     4680

gtactttagc tattgtttgc ctgcacatac atgttgtaat atgcacagtg attacaacct     4740

ttaaagcaag aggaggcgag ttaatttgga tgagtgtgat tttgctgatt gaatgtgagt     4800

tttcaaatag gagtcttttt ctgcaatttg tttgcatttt ttagaagtgc aaacagtaag     4860

taaataaaag ccttcggtaa taatcatgac aatacaagag gctgagctag gctacagggg     4920

aaaactattg tgttgtaaag ttgcatcgct attttatatt aaaatgtaat gatcagcatc     4980

atgaacaatg agctcttagt gttttattta tctgaaaaaa tgtaagtaaa agcagtgtta     5040

gtgagaggtg caaagaatta ttctaacaga cacctgaaag tatctgtaag caatactagt     5100

aggtaagatt tcactgtgtg tacacataca catttgagat tgtatgagaa catataatcc     5160

atatgatatg ttgtacattt tatggaaatg taatagaatc tcacacatta ttttatagaa     5220

atagagtaca gaagcatcac aagtattaaa gttggtttta gcaaggatta ggattactac     5280

aattattttt actataataa ttatttttct tctatggaac tcagaatcct ggctacattt     5340

gaggacagga atatgttgag cctgattttc ctggtgtgtg taaaatattt cctaggaata     5400

aattaggcac tttttagaag caatgttaaa tcattcaggt tttattttct gccctgaagc     5460

agaaatttaa aaaatgatat tgggacctgg aaggtttaat atggttcaca gtgcctgaat     5520

tacacctgct ccgaaaacta gctttgtatt tcttatgact ttgcataaga actgttcatc     5580

tttggatctt gagcacctta cagataaaac tttttatggc atctctttca tggacagtga     5640

tattgatctt ttcacaatgt acgtagcctc tagaattttg tacatatgtt tgctcttttt     5700

ttgtacagac tagttgttga gaaaacaggg gcgtttccta atttggtctt tatcctgcga     5760

caacactttc agcagactag cctctcctta tctcacagat cacaagcacc cctagatagt     5820

gtgattctgt cagatagcat ttatgcaaaa atctatgaag ttaaaagatc gtagaagcca     5880

aatgaaatgt acatatctac tgactgatga caagggaatt tcattaggaa gaaggtaaag     5940

aaacatcgtt gagtagccta ccttgatttc tgtcaagttc ataaccagct tcatatttta     6000

aaggcttcag gtttgaaatt aagtcaactg catgcagctt tgctgataaa tgaataattc     6060

tctttgatgc catttatgag aaaagacttc aatatctgtt gcctgtcata tttaagaaaa     6120

attactgttt ctactctctg tatctgattt taaaagaaaa aactattcat acctggcttc     6180

caggtaattg actttgaatt cttacaagca aaggtcattg tgtttttctt gaatagacat     6240

ctaataaatt ttgcttggaa gtatacttca gtttttcttc ttgacattta tctttataaa     6300

aattgtgtat tttattccaa cttgttaaac taagagaaaa tgca                      6344


<210>  2391
<211>  3271
<212>  DNA
<213>  homo sapiens

<400>  2391
gctgtgacag ccacacgccc caaggcctcc aagatgagct acacgttgga ctcgctgggc       60

aacccgtccg cctaccggcg ggtaaccgag acccgctcga gcttcagccg cgtcagcggc      120

tccccgtcca gtggcttccg ctcgcagtcg tggtcccgcg gctcgcccag caccgtgtcc      180

tcctcctata agcgcagcat gctcgccccg cgcctcgctt acagctcggc catgctcagc      240

tccgccgaga gcagccttga cttcagccag tcctcgtccc tgctcaacgg cggctccgga      300

cccggcggcg actacaagct gtcccgctcc aacgagaagg agcagctgca ggggctgaac      360

gaccgctttg ccggctacat agagaaggtg cactacctgg agcagcagaa taaggagatt      420

gaggcggaga tccaggcgct gcggcagaag caggcctcgc acgcccagct gggcgacgcg      480

tacgaccagg agatccgcga gctgcgcgcc accctggaga tggtgaacca cgagaaggct      540

caggtgcagc tggactcgga ccacctggag gaagacatcc accggctcaa ggagcgcttt      600

gaggaggagg cgcggttgcg cgacgacact gaggcggcca tccgcgcgct gcgcaaagac      660

atcgaggagg cgtcgctggt caaggtggag ctggacaaga aggtgcagtc gctgcaggat      720

gaggtggcct tcctgcggag caaccacgag gaggaggtgg ccgaccttct ggcccagatc      780

caggcatcgc acatcacggt ggagcgcaaa gactacctga agacagacat ctcgacggcg      840

ctgaaggaaa tccgctccca gctcgaaagc cactcagacc agaatatgca ccaggccgaa      900

gagtggttca aatgccgcta cgccaagctc accgaggcgg ccgagcagaa caaggaggcc      960

atccgctccg ccaaggaaga gatcgccgag taccggcgcc agctgcagtc caagagcatc     1020

gagctagagt cggtgcgcgg caccaaggag tccctggagc ggcagctcag cgacatcgag     1080

gagcgccaca accacgacct cagcagctac caggacacca tccagcagct ggaaaatgag     1140

cttcggggca caaagtggga aatggctcgt catttgcgcg aataccagga cctcctcaac     1200

gtcaagatgg ctctggatat agaaatcgct gcgtacagaa aactcctgga gggtgaagag     1260

actagattta gcacatttgc aggaagcatc actgggccac tgtatacaca ccgaccccca     1320

atcacaatat ccagtaagat tcagaaaccc aaggtggaag ctcccaagct taaggtccaa     1380

cacaaatttg tcgaggagat catagaggaa accaaagtgg aggatgagaa gtcagaaatg     1440

gaagaggccc tgacagccat tacagaggaa ttggccgttt ccatgaagga agagaagaaa     1500

gaagcagcag aagaaaagga agaggaaccc gaagctgaag aagaagaagt agctgccaaa     1560

aagtctccag tgaaagcaac tgcacctgaa gttaaagaag aggaagggga aaaggaggaa     1620

gaagaaggcc aggaagaaga ggaggaagaa gatgagggag ctaagtcaga ccaagccgaa     1680

gagggaggat ccgagaagga aggctctagt gaaaaagagg aaggtgagca ggaagaagga     1740

gaaacagaag ctgaagctga aggagaggaa gccgaagcta aagaggaaaa gaaagtggag     1800

gaaaagagtg aggaagtggc taccaaggag gagctggtgg cagatgccaa ggtggaaaag     1860

ccagaaaaag ccaagtctcc tgtgccaaaa tcaccagtgg aagagaaagg caagtctcct     1920

gtgcccaagt caccagtgga agagaaaggc aagtctcctg tgcccaagtc accagtggaa     1980

gagaaaggca agtctcctgt gccgaaatca ccagtggaag agaaaggcaa gtctcctgtg     2040

tcaaaatcac cagtggaaga gaaagccaaa tctcctgtgc caaaatcacc agtggaagag     2100

gcaaagtcaa aagcagaagt ggggaaaggt gaacagaaag aggaagaaga aaaggaagtc     2160

aaggaagctc ccaaggaaga gaaggtagag aaaaaggaag agaaaccaaa ggatgtgcca     2220

gagaagaaga aagctgagtc ccctgtaaag gaggaagctg tggcagaggt ggtcaccatc     2280

accaaatcgg taaaggtgca cttggagaaa gagaccaaag aagaggggaa gccactgcag     2340

caggagaaag agaaggagaa agcgggagga gagggaggaa gtgaggagga agggagtgat     2400

aaaggtgcca agggatccag gaaggaagac atagctgtca atggggaggt agaaggaaaa     2460

gaggaggtag agcaggagac caaggaaaaa ggcagtggga gggaagagga gaaaggcgtt     2520

gtcaccaatg gcctagactt gagcccagca gatgaaaaga aggggggtga taaaagtgag     2580

gagaaagtgg tggtgaccaa aacggtagaa aaaatcacca gtgagggggg agatggtgct     2640

accaaataca tcactaaatc tgtaaccgtc actcaaaagg ttgaagagca tgaagagacc     2700

tttgaggaga aactagtgtc tactaaaaag gtagaaaaag tcacttcaca cgccatagta     2760

aaggaagtca cccagagtga ctaagatttg agtccattgc aaaaggttaa gccatatgac     2820

aatttcaaaa tgcatgtgat tggcagcttc aaaacagaac gggttctccc atgggggctc     2880

cagacattgt attttacttt gtgcaatatg aggggactgc atgcaagctc agggtgctcc     2940

ctcctcagtc tttgggggat tcaaatgcat gatattgtat gtacctggga aatttgccga     3000

tttcctaagc tgttggaagg gggtcactta aggggggatg tcttgagatg tattatgcaa     3060

agtaccaact gagccaaaaa caataaacga aacacagaac tcagccttaa gaaagctata     3120

tatgaataat tatgtttacc tcactggtgc atttaaaatg gacttttgtt catgggagaa     3180

cctcgttgac atgcacagtt tgcaatctta tgttgatcga tgttaaacgt cacagcagta     3240

cttgctcaat aaaggtcata ttggaaacat a                                    3271


<210>  2392
<211>  9512
<212>  DNA
<213>  homo sapiens

<400>  2392
aaccctgctc ctcgctgaag atggaggaag taaaaacagg attaccctta gctacagatc       60

cactgcctta gtttccacca ccaactgcag tgcacaaaca cacgttaggc acaggaaaga      120

aagaaagaca gaggacacat taacagtaaa cacaaacaaa agggtgatgg gattatttta      180

ctgcatgcac tgctgagccc gacattgtca cctcctcttt gaggggttag aagaagctga      240

gatctcccga cagagctgga aatggtgatg aatctttttt aatcaaagga caatttcttt      300

tcattgcact ttgactatgg aaacagaggc tattgatggc tatataacgt gtgacaatga      360

gctttcaccc gaaagggagc actccaatat ggcaattgac ctcacctcaa gcacacccaa      420

tggacagcat gcctcaccaa gtcacatgac aagcacaaat tcagtaaagc tagaaatgca      480

gagtgatgaa gagtgtgaca ggaaacccct gagccgtgaa gatgagatca ggggccatga      540

tgagggtagc agcctagaag aacccctaat tgagagcagc gaggtggctg acaacaggaa      600

agtccaggag cttcaaggcg agggaggaat ccggcttccg aatggtgaac gccccttcca      660

ctgtaaccag tgtggagctt cttttactca gaagggcaac cttctgagac acataaagtt      720

acactctgga gagaagccgt tcaaatgtcc tttctgtagc tacgcctgta gaagaaggga      780

cgccctcaca ggacacctca ggacccattc tgtgggtaaa cctcacaagt gcaactactg      840

tggacgaagc tacaagcagc gcagttcact ggaggagcac aaggaacgct gccacaacta      900

tctccagaat gtcagcatgg aggctgctgg gcaggtcatg agtcaccatg tacctcctat      960

ggaagattgt aaggaacaag agcctattat ggacaacaat atttctctgg tgccttttga     1020

gagacctgct gtcatagaga agctcacggg gaatatggga aaacgtaaaa gctccactcc     1080

acaaaagttt gtgggggaaa agctcatgcg attcagctac ccagatattc actttgatat     1140

gaacttaaca tatgagaagg aggctgagct gatgcagtct catatgatgg accaagccat     1200

caacaatgca atcacctacc ttggagctga ggcccttcac cctctgatgc agcacccgcc     1260

aagcacaatc gctgaagtgg ccccagttat aagctcagct tattctcagg tctatcatcc     1320

aaataggata gaaagaccca ttagcaggga aactgctgat agtcatgaaa acaacatgga     1380

tggccccatc tctctcatca gaccaaagag tcgaccccag gaaagagagg cctctcccag     1440

caatagctgc ctggattcca ctgactcaga aagcagccat gatgaccacc agtcctacca     1500

aggacaccct gccttaaatc ccaagaggaa acaaagccca gcttacatga aggaggatgt     1560

caaagctttg gatactacca aggctcctaa gggctctctg aaggacatct acaaggtctt     1620

caatggagaa ggagaacaga ttagggcctt caagtgtgag cactgccgag tccttttcct     1680

agaccatgtc atgtacacca ttcacatggg ttgccatggc taccgggacc cactggaatg     1740

caacatctgt ggctacagaa gccaggaccg ttatgagttt tcatcacaca ttgttcgagg     1800

ggagcacaca ttccactagg ccttttcatt ccaaagggga cccctatgaa gtaaagaact     1860

gcacatgaag aaatactgca cttacaatcc cacctttcct caaatgttga catacctttt     1920

atttttttta atattattac tgttgataat tcttattttg tggaggcagt gtcatttgct     1980

ctgcctaatt acgataagga agaaacagaa gagagaaggg gcgggaatat tgtttcttta     2040

tcacctggct tgtttatttt gtgggaattt aagagcagtc catttctacc aaggcatatc     2100

atgctttgaa aaatcacttg attcataaag attcacctaa gagattctga tttgccactg     2160

atattcagaa ttatgatgga agacaggaaa gttcagagtt ttctgggtag gactttggtg     2220

gtttaaaaat ggtataagta actttattct tgaaagaaga atgtgtttca aactgtaaac     2280

caattttttg ttcttcagag atcatggaac acaaacacat tgttattttc agtgataact     2340

cctaagagga gctgagttgt tgtgggttct atgtttactt cccctatgga atttataatt     2400

cagtatgttt tacactgtac catatagcaa aacttttaaa ctacaggtag ttaagggcca     2460

cctacaatac atctgaggtc ctgtgatctt atttttctaa acgtaagcac tgtttttcca     2520

tagttttgat gactggcatt ttatagacac cctggcagcc ttacttttaa cacctttaag     2580

gaatagtatt tttatgtagt tttcagaata acatatggtc taagagtgga taaaaggcag     2640

tcaataattt ctgggaggga cttctacttt cataaatttg tttgagaggt tttcttttaa     2700

agttgtaatg tgatggcagc atagtatatg tatttgtttc taaaagtatg cttacgattg     2760

tcactttatc agcatttaat cagtgttaac cagtcagcag aaaaatataa ttatgctaac     2820

agtaggggga gaaaacccac ttagaaatcc cttttctggt atttctcttt tcactagttt     2880

ttttcaagat gtgacctccc ggtgttctgt ccatagttca ttcatccttt actcttcgag     2940

tagaaggtct taaaagtctt cctgtcggct gtttctttca aaatctcctc agagcaattg     3000

ctaatttggc ctgaatctgg taacttgaac cctgtaaggt tacagaacta gggctattta     3060

ttttagcatt tcttcagtag tatttactac tcttgttgca aagaaaaggg aatgggactt     3120

ctttgtaacc tgtaccttgg acaacagata aaagaaacaa aaaaataaga aagtttactt     3180

ttacccttct tggagtctag aatgtgacag aacccccaaa ggaaagtcct gcacattttt     3240

ctgtttccaa aacatttaat tgtgtaagtc cttgtcagaa atgaatctca atcccttagt     3300

atagaattcc ccttacatgg tataggttgc catatttcat gtgcagattt taatttcatt     3360

tatgtgggcg ctctgttttt tctttgcagt ccagccacat tagaggggag gaaccgagtg     3420

atattgattc aagtcatttt agggggacat acttggaagg cagaacttgc tgcttctgtt     3480

tggggaggac agacctgact gtgactggat tatctgataa ccatttgtga atactgaaat     3540

tctgttaggc agtaactgat aactgctcta aaggatcatt aaataggatg ctgaaattat     3600

gtatcttaat acagtgtggt atgagaatta ccaagtcaag agaattgtgg acataagcaa     3660

gtttggcccc aatactgctc ttaactcatt ttccagctta ctatttgcta tttaaatggt     3720

aggcaccagc taagcacttc taagcactaa cacagctaga actaggcaaa aatggttaga     3780

actcagctct cttctactag tccctgtcat aattattttt gggaaaatgt ccaaactgcc     3840

ccctttaaat ctaagggaat gcaccaaaac agagatatat agaatgtcaa ccatttcatt     3900

tttttttttc tgcatgcctt ggtacatagt gaacatacaa cctatttaaa gataaagcat     3960

gtttttgaga ctcgctcacc cccccccacc caaccactcc caaataataa ttgggatgcc     4020

attttttttc cttttggatg aggtaaataa ttttaaggtt cacaattttg tcttttactg     4080

caatttaagg aaacatttgg atgtcagtca atatgttcat aattttggct gtgtgcgaat     4140

ttctgctggc attatctatg aattttcttc ctacttattt ttttttcagt atatgaacaa     4200

tcatgtatct acctgcccca ggatgaaact aaatttaggt ggaccctaaa ccttatgaag     4260

acagtgctga ggcactttcc ttttctgatt tcatcttttt gggaatctgt tttattgaag     4320

gtagttagta gttgagagtg catttgctac aagcatatac ttgtatcttc ctagcttcat     4380

gaggaacaga aagaggtgga tatggctcag ggtgtggcag ggacaattga ggacaaagtc     4440

aattcaaatt tgtgggtcag aaagaatttt tgtggacgta gtgtttttgg agaaactctg     4500

gatggttata tgtgcatgcc ttttcttcaa aaggaaatac gcaaggttgt agcatctaaa     4560

aataaacata agagtcagac accaaataaa tcaagtttta cataacagtt gtatgcccag     4620

tttgtttagg tgagatttca cattacagaa agtatttgag gagcatgaaa atgggttatc     4680

ttctgtattt tccagtttgg caaaagttca gaatttcatc acattgcttt gccctaattt     4740

tgcccagaat tttatcttag cctctctctg acagtgatga atcatgctca aaagccattc     4800

taattggacc tttttaagac agggaaaggg atcagtaggc ggattggaag aaatttcaag     4860

tcattgaaat attccattga gatttcctaa agggacaaaa ttgggaaaat aagaaactac     4920

gacttagatt tggctacgta gtagaaagta tctcccctac atacatacag gcaattgtat     4980

gtatgaatca tagggtatat gtgtgtgtat actacacaca cattctttta aagagaattc     5040

atggaaaaaa aagcagttgg agtgatcaga tgtattgcaa aaacatacag agaatttaaa     5100

tgacagttaa taccaagaaa ttagttgggt ttactttatc aggtcgtaat aggaatcact     5160

aaagaagtta ctagtgtgtc tttaggacca gtggcaactc ttaaactaaa actttgggtc     5220

cttattatct acttacagaa caaagtgaaa caaacaatga ttaagctgat tggatataca     5280

ttcaaagata tttaatgtaa agttttttgg aatacgaaga aaattcagaa aataaatatt     5340

atcaacagtt acttattggc aaatagagaa agacaagaat agtttagtga gcccggtatt     5400

ttgtttttat agtttttatc tcagttgtac aactcacaaa accatgaagt ctttggtatt     5460

ttataaatgt ttaacaaaat ttacatcaga ttaaggcatt tagatgaaaa ttattatgtt     5520

ctcactatct tccaaatttt atttcatcct atctccaaaa tgatttctta gggtacaaaa     5580

agagcagacg gggctgtaaa aatacaagca aaaaactgtg tgcccctagt ttcaggcaga     5640

acttaaactg tcagaggtac tagctacatg atttgttttt taactttgga ttgttcacgt     5700

ccaaaaatgg ataaattaca tttgtgttta tcatcagttg cattttatgt attattttaa     5760

taaatactat ctgaatgaag actattctaa accagaaaat tccccaaatc caaaagaaaa     5820

aaaaagtggg aagaggtgaa attgaagttt gtgtatatga aagttatctt agacatattt     5880

ttaattctcc agtttctgca aaataattaa aatatacagt aactggtctc ctaaatcctg     5940

aatttaatgt attaaatact tatgttcttt atattggtgc ctttttaaaa tgcattgaga     6000

gtgttggtta gctgttgcag ctgtacaaca cttttaatat gcatttttaa aaatcactta     6060

aaattgagta ctatataatt catctctgca tttttagtgc aaatctttag agcaatttct     6120

aatagagaaa ttttcagctc agctgttaaa aggaaaagga aactttgaaa ctagacttta     6180

ctaccttttt agtttcatag tatttctgaa tatgattaca agattatgca ggtaaaatat     6240

agagtgaaac tttacctgtg aattgaatta taatttgtgt ttttgttttg tttttaagga     6300

agaataagtt ctgtatcaaa caagaattta ttagataatt ttttggtcaa taaaatacag     6360

tattcatttg gattttcatc tccagactag tattgttcta gtcttggaat ctgtattttc     6420

taatctgtta gaaaatagag attgaaaatt gatggaataa tgtgaaaaag caggtaatta     6480

attctccttg aacaaagcaa aactgaacag tcatatcaca ttgctattct ccaaagcata     6540

atctcaaatg gtttcatatc atggttgtgt attacttgca atgggtgtgt taggatatga     6600

cagcttttta aaaaaatgag ctgctggtta tacaaagcaa atggcatatg accaagaagc     6660

tgtgatatgc tagtgtttct ttttatcata gtgtattact aggccaaata atgacacctt     6720

gaatattttt acatttattg cagaaacctt aaactttgga atttccataa ggtttttatg     6780

taatattcta tttctagctt tttagtttta tcttgctgta ctgtaagttt gaggatattt     6840

ttcacctgca ctcttaggaa taagttcata attctgttta tggggctttc ctcccataac     6900

actgcatttg tatattttct gtataaaata tgtgttgtgt attaaccttt atcccataca     6960

gagagtggta catgaatgac tagttttcta agatgtcctt tttattgtga ataaaatata     7020

aaagttaaag gccctctgct aagtcacata aagtacagca tataagttca tataggtaca     7080

aataaatgag tttgcagtga attgggcctt caaattacct caagtgacag atagtaagaa     7140

aagcttcttg agcaggtgga ggtcactgaa tcccctacta tgcacttacc aagattttac     7200

ttactttaat ttactggaaa ttgatttttt aaaaaatgac tacactgtaa caagggaagg     7260

gatctgggtt tttttgttgt tttattcttg ttttttttaa gtagttcaaa ttctgaaact     7320

gtgatttaaa aattttttac agtcaagcat tctgattttg aacataactc ccttcccttt     7380

ctgtgtaaca aaggtctctc tgttatctct taaattttgt tacatctccc tcagcctctt     7440

tctttgtccg tctcccttct gtcattgtct atggatgttt acctctctgt tctcctaaaa     7500

gtttgaagat taggtcaact cttatttcta gttcattggt aatttaatct taattttttt     7560

ttcgtgattt ttgttggttg tataatctgc tgacgtattt ttatactcaa gtgtagtttt     7620

ctattaaaaa gaaaagtggt tggattaaaa atagtaagct atgtaaccct catgttactt     7680

tcactttcaa atattgggta cctaaaacat tacttcagag attatgtaat cctattatag     7740

tatgtttgct ttcctttatt gttggatttt acattctgat ttggctttcc tccaaaaaat     7800

gtatatcatg aaagactaga cagttatttg caagtgttta gaaaggtgtt aaaaatgtaa     7860

agcaaagagt cttaactttc tcctaattgg gagaaaaatg ctttaacatt actataataa     7920

tattccaggt ttggaggggg tctccaggcc ccatatttgc tgttaatagt tggacctttt     7980

agaccatgtg ttatttgcaa tcccagaatg attgcttctg ctattagtta aaaagatact     8040

attcttttct ttctgtacaa gtgcaatact ccccttgaag tcttaaaaac tatggtgatt     8100

tttttttctt ttctgaccta ttcttccttt agctaatgac aaaaagaaac tcataaaagt     8160

catagtatgt taaaggacac aacaagcaaa gagaaaaaca ctccacaatc aaaagattac     8220

agaatgtgga aaccactagt ctgatctcat ggtatcttta tttaagctaa atttccatgg     8280

aaattagtaa tcttttgctt gaaaaatgtg tcctaaagtt gaacttttta cagattgaat     8340

cttcttagac cctcgcccaa tgctctaaat taagaaccta atacttaata tttttatttt     8400

acttctcccc ttttagaaat aaacttttaa ataaaagcaa agcacttagc tgagttttaa     8460

acacttacat atcacctatt ggagaaattt tttttaaaaa tatttggagc agtcctgttt     8520

tcatacaaat ttaagtaaga ggtatttttc ttatacatat ttatatgtag tgtgctaatt     8580

ttcttttttt atacctgtgt ccctgtagta aaactgctgt aatataaata catgttttgt     8640

taaaagataa catttctttg gcatttcttt taaaggcagt tactgcattt ctgcatttgt     8700

acagtatgtg tcttggccat tttagatatt ctttctttaa caataccaaa ggtaattaga     8760

ctattttaaa gactaattgc ttgacagttt ctagggtatt ttgtgtttta gaagcaaaaa     8820

aagaaaaaaa aataggtcaa accagtaaac ctcatttttt ttcaaactaa taatttgggg     8880

aaataaaaac tattgtttaa aaaagaaata tatatatata tatataaata tatatgtaaa     8940

gttaaaattc cataccttgt atgtcaggtt tgctaagtgt aatgtagttt ttttaaggct     9000

caaataccat acctcagaaa atgaggttta ctatggaaat actgaaacag tctttgcagc     9060

tgtgtgacaa gtcactctac tacatactga tttggagacc tccgctaaat agttttatca     9120

ctgcagacta aaatgtggga cttgtatctt ctttgttttt aatgcacaca catacatgtt     9180

ctgtgcatgt atgtggttac tgtgtatatg tgtatgagtg ttgtatatgc atgtgtgagt     9240

gtgtgtctgt atgtgtgtac aactaaagaa gctgcagaaa ctttgtaata ctttgtgaaa     9300

aggattatat tataaaggtt tgtactgtct gagtgcacag ctactggaat aaatttaggg     9360

aatctcagga acaagcatat aatttgtcca agatttattt cttctcagaa gtgtaagtgc     9420

agtttttaat tctgtatatt atttaatatt ttaccaataa aataaacttc tgacataaaa     9480

agtttgctat aaaaaaaaaa aaaaaaaaaa aa                                   9512


<210>  2393
<211>  9443
<212>  DNA
<213>  homo sapiens

<400>  2393
gggcttggct tggagggggc aagggaggga aagagagaag ggggaaacac aaaaaacttc       60

tttctttctc cctccgttta tcttcagccc gacattgtca cctcctcttt gaggggttag      120

aagaagctga gatctcccga cagagctgga aatgcattgc actttgacta tggaaacaga      180

ggctattgat ggctatataa cgtgtgacaa tgagctttca cccgaaaggg agcactccaa      240

tatggcaatt gacctcacct caagcacacc caatggacag catgcctcac caagtcacat      300

gacaagcaca aattcagtaa agctagaaat gcagagtgat gaagagtgtg acaggaaacc      360

cctgagccgt gaagatgaga tcaggggcca tgatgagggt agcagcctag aagaacccct      420

aattgagagc agcgaggtgg ctgacaacag gaaagtccag gagcttcaag gcgagggagg      480

aatccggctt ccgaatggta aactgaaatg tgacgtctgt ggcatggttt gcattgggcc      540

caatgtgctt atggtacata aaaggagtca cactggtgaa cgccccttcc actgtaacca      600

gtgtggagct tcttttactc agaagggcaa ccttctgaga cacataaagt tacactctgg      660

agagaagccg ttcaaatgtc ctttctgtag ctacgcctgt agaagaaggg acgccctcac      720

aggacacctc aggacccatt ctgtgggtaa acctcacaag tgcaactact gtggacgaag      780

ctacaagcag cgcagttcac tggaggagca caaggaacgc tgccacaact atctccagaa      840

tgtcagcatg gaggctgctg ggcaggtcat gagtcaccat gtacctccta tggaagattg      900

taaggaacaa gagcctatta tggacaacaa tatttctctg gtgccttttg agagacctgc      960

tgtcatagag aagctcacgg ggaatatggg aaaacgtaaa agctccactc cacaaaagtt     1020

tgtgggggaa aagctcatgc gattcagcta cccagatatt cactttgata tgaacttaac     1080

atatgagaag gaggctgagc tgatgcagtc tcatatgatg gaccaagcca tcaacaatgc     1140

aatcacctac cttggagctg aggcccttca ccctctgatg cagcacccgc caagcacaat     1200

cgctgaagtg gccccagtta taagctcagc ttattctcag gtctatcatc caaataggat     1260

agaaagaccc attagcaggg aaactgctga tagtcatgaa aacaacatgg atggccccat     1320

ctctctcatc agaccaaaga gtcgacccca ggaaagagag gcctctccca gcaatagctg     1380

cctggattcc actgactcag aaagcagcca tgatgaccac cagtcctacc aaggacaccc     1440

tgccttaaat cccaagagga aacaaagccc agcttacatg aaggaggatg tcaaagcttt     1500

ggatactacc aaggctccta agggctctct gaaggacatc tacaaggtct tcaatggaga     1560

aggagaacag attagggcct tcaagtgtga gcactgccga gtccttttcc tagaccatgt     1620

catgtacacc attcacatgg gttgccatgg ctaccgggac ccactggaat gcaacatctg     1680

tggctacaga agccaggacc gttatgagtt ttcatcacac attgttcgag gggagcacac     1740

attccactag gccttttcat tccaaagggg acccctatga agtaaagaac tgcacatgaa     1800

gaaatactgc acttacaatc ccacctttcc tcaaatgttg acataccttt tatttttttt     1860

aatattatta ctgttgataa ttcttatttt gtggaggcag tgtcatttgc tctgcctaat     1920

tacgataagg aagaaacaga agagagaagg ggcgggaata ttgtttcttt atcacctggc     1980

ttgtttattt tgtgggaatt taagagcagt ccatttctac caaggcatat catgctttga     2040

aaaatcactt gattcataaa gattcaccta agagattctg atttgccact gatattcaga     2100

attatgatgg aagacaggaa agttcagagt tttctgggta ggactttggt ggtttaaaaa     2160

tggtataagt aactttattc ttgaaagaag aatgtgtttc aaactgtaaa ccaatttttt     2220

gttcttcaga gatcatggaa cacaaacaca ttgttatttt cagtgataac tcctaagagg     2280

agctgagttg ttgtgggttc tatgtttact tcccctatgg aatttataat tcagtatgtt     2340

ttacactgta ccatatagca aaacttttaa actacaggta gttaagggcc acctacaata     2400

catctgaggt cctgtgatct tatttttcta aacgtaagca ctgtttttcc atagttttga     2460

tgactggcat tttatagaca ccctggcagc cttactttta acacctttaa ggaatagtat     2520

ttttatgtag ttttcagaat aacatatggt ctaagagtgg ataaaaggca gtcaataatt     2580

tctgggaggg acttctactt tcataaattt gtttgagagg ttttctttta aagttgtaat     2640

gtgatggcag catagtatat gtatttgttt ctaaaagtat gcttacgatt gtcactttat     2700

cagcatttaa tcagtgttaa ccagtcagca gaaaaatata attatgctaa cagtaggggg     2760

agaaaaccca cttagaaatc ccttttctgg tatttctctt ttcactagtt tttttcaaga     2820

tgtgacctcc cggtgttctg tccatagttc attcatcctt tactcttcga gtagaaggtc     2880

ttaaaagtct tcctgtcggc tgtttctttc aaaatctcct cagagcaatt gctaatttgg     2940

cctgaatctg gtaacttgaa ccctgtaagg ttacagaact agggctattt attttagcat     3000

ttcttcagta gtatttacta ctcttgttgc aaagaaaagg gaatgggact tctttgtaac     3060

ctgtaccttg gacaacagat aaaagaaaca aaaaaataag aaagtttact tttacccttc     3120

ttggagtcta gaatgtgaca gaacccccaa aggaaagtcc tgcacatttt tctgtttcca     3180

aaacatttaa ttgtgtaagt ccttgtcaga aatgaatctc aatcccttag tatagaattc     3240

cccttacatg gtataggttg ccatatttca tgtgcagatt ttaatttcat ttatgtgggc     3300

gctctgtttt ttctttgcag tccagccaca ttagagggga ggaaccgagt gatattgatt     3360

caagtcattt tagggggaca tacttggaag gcagaacttg ctgcttctgt ttggggagga     3420

cagacctgac tgtgactgga ttatctgata accatttgtg aatactgaaa ttctgttagg     3480

cagtaactga taactgctct aaaggatcat taaataggat gctgaaatta tgtatcttaa     3540

tacagtgtgg tatgagaatt accaagtcaa gagaattgtg gacataagca agtttggccc     3600

caatactgct cttaactcat tttccagctt actatttgct atttaaatgg taggcaccag     3660

ctaagcactt ctaagcacta acacagctag aactaggcaa aaatggttag aactcagctc     3720

tcttctacta gtccctgtca taattatttt tgggaaaatg tccaaactgc cccctttaaa     3780

tctaagggaa tgcaccaaaa cagagatata tagaatgtca accatttcat tttttttttt     3840

ctgcatgcct tggtacatag tgaacataca acctatttaa agataaagca tgtttttgag     3900

actcgctcac ccccccccac ccaaccactc ccaaataata attgggatgc catttttttt     3960

ccttttggat gaggtaaata attttaaggt tcacaatttt gtcttttact gcaatttaag     4020

gaaacatttg gatgtcagtc aatatgttca taattttggc tgtgtgcgaa tttctgctgg     4080

cattatctat gaattttctt cctacttatt tttttttcag tatatgaaca atcatgtatc     4140

tacctgcccc aggatgaaac taaatttagg tggaccctaa accttatgaa gacagtgctg     4200

aggcactttc cttttctgat ttcatctttt tgggaatctg ttttattgaa ggtagttagt     4260

agttgagagt gcatttgcta caagcatata cttgtatctt cctagcttca tgaggaacag     4320

aaagaggtgg atatggctca gggtgtggca gggacaattg aggacaaagt caattcaaat     4380

ttgtgggtca gaaagaattt ttgtggacgt agtgtttttg gagaaactct ggatggttat     4440

atgtgcatgc cttttcttca aaaggaaata cgcaaggttg tagcatctaa aaataaacat     4500

aagagtcaga caccaaataa atcaagtttt acataacagt tgtatgccca gtttgtttag     4560

gtgagatttc acattacaga aagtatttga ggagcatgaa aatgggttat cttctgtatt     4620

ttccagtttg gcaaaagttc agaatttcat cacattgctt tgccctaatt ttgcccagaa     4680

ttttatctta gcctctctct gacagtgatg aatcatgctc aaaagccatt ctaattggac     4740

ctttttaaga cagggaaagg gatcagtagg cggattggaa gaaatttcaa gtcattgaaa     4800

tattccattg agatttccta aagggacaaa attgggaaaa taagaaacta cgacttagat     4860

ttggctacgt agtagaaagt atctccccta catacataca ggcaattgta tgtatgaatc     4920

atagggtata tgtgtgtgta tactacacac acattctttt aaagagaatt catggaaaaa     4980

aaagcagttg gagtgatcag atgtattgca aaaacataca gagaatttaa atgacagtta     5040

ataccaagaa attagttggg tttactttat caggtcgtaa taggaatcac taaagaagtt     5100

actagtgtgt ctttaggacc agtggcaact cttaaactaa aactttgggt ccttattatc     5160

tacttacaga acaaagtgaa acaaacaatg attaagctga ttggatatac attcaaagat     5220

atttaatgta aagttttttg gaatacgaag aaaattcaga aaataaatat tatcaacagt     5280

tacttattgg caaatagaga aagacaagaa tagtttagtg agcccggtat tttgttttta     5340

tagtttttat ctcagttgta caactcacaa aaccatgaag tctttggtat tttataaatg     5400

tttaacaaaa tttacatcag attaaggcat ttagatgaaa attattatgt tctcactatc     5460

ttccaaattt tatttcatcc tatctccaaa atgatttctt agggtacaaa aagagcagac     5520

ggggctgtaa aaatacaagc aaaaaactgt gtgcccctag tttcaggcag aacttaaact     5580

gtcagaggta ctagctacat gatttgtttt ttaactttgg attgttcacg tccaaaaatg     5640

gataaattac atttgtgttt atcatcagtt gcattttatg tattatttta ataaatacta     5700

tctgaatgaa gactattcta aaccagaaaa ttccccaaat ccaaaagaaa aaaaaagtgg     5760

gaagaggtga aattgaagtt tgtgtatatg aaagttatct tagacatatt tttaattctc     5820

cagtttctgc aaaataatta aaatatacag taactggtct cctaaatcct gaatttaatg     5880

tattaaatac ttatgttctt tatattggtg cctttttaaa atgcattgag agtgttggtt     5940

agctgttgca gctgtacaac acttttaata tgcattttta aaaatcactt aaaattgagt     6000

actatataat tcatctctgc atttttagtg caaatcttta gagcaatttc taatagagaa     6060

attttcagct cagctgttaa aaggaaaagg aaactttgaa actagacttt actacctttt     6120

tagtttcata gtatttctga atatgattac aagattatgc aggtaaaata tagagtgaaa     6180

ctttacctgt gaattgaatt ataatttgtg tttttgtttt gtttttaagg aagaataagt     6240

tctgtatcaa acaagaattt attagataat tttttggtca ataaaataca gtattcattt     6300

ggattttcat ctccagacta gtattgttct agtcttggaa tctgtatttt ctaatctgtt     6360

agaaaataga gattgaaaat tgatggaata atgtgaaaaa gcaggtaatt aattctcctt     6420

gaacaaagca aaactgaaca gtcatatcac attgctattc tccaaagcat aatctcaaat     6480

ggtttcatat catggttgtg tattacttgc aatgggtgtg ttaggatatg acagcttttt     6540

aaaaaaatga gctgctggtt atacaaagca aatggcatat gaccaagaag ctgtgatatg     6600

ctagtgtttc tttttatcat agtgtattac taggccaaat aatgacacct tgaatatttt     6660

tacatttatt gcagaaacct taaactttgg aatttccata aggtttttat gtaatattct     6720

atttctagct ttttagtttt atcttgctgt actgtaagtt tgaggatatt tttcacctgc     6780

actcttagga ataagttcat aattctgttt atggggcttt cctcccataa cactgcattt     6840

gtatattttc tgtataaaat atgtgttgtg tattaacctt tatcccatac agagagtggt     6900

acatgaatga ctagttttct aagatgtcct ttttattgtg aataaaatat aaaagttaaa     6960

ggccctctgc taagtcacat aaagtacagc atataagttc atataggtac aaataaatga     7020

gtttgcagtg aattgggcct tcaaattacc tcaagtgaca gatagtaaga aaagcttctt     7080

gagcaggtgg aggtcactga atcccctact atgcacttac caagatttta cttactttaa     7140

tttactggaa attgattttt taaaaaatga ctacactgta acaagggaag ggatctgggt     7200

ttttttgttg ttttattctt gtttttttta agtagttcaa attctgaaac tgtgatttaa     7260

aaatttttta cagtcaagca ttctgatttt gaacataact cccttccctt tctgtgtaac     7320

aaaggtctct ctgttatctc ttaaattttg ttacatctcc ctcagcctct ttctttgtcc     7380

gtctcccttc tgtcattgtc tatggatgtt tacctctctg ttctcctaaa agtttgaaga     7440

ttaggtcaac tcttatttct agttcattgg taatttaatc ttaatttttt tttcgtgatt     7500

tttgttggtt gtataatctg ctgacgtatt tttatactca agtgtagttt tctattaaaa     7560

agaaaagtgg ttggattaaa aatagtaagc tatgtaaccc tcatgttact ttcactttca     7620

aatattgggt acctaaaaca ttacttcaga gattatgtaa tcctattata gtatgtttgc     7680

tttcctttat tgttggattt tacattctga tttggctttc ctccaaaaaa tgtatatcat     7740

gaaagactag acagttattt gcaagtgttt agaaaggtgt taaaaatgta aagcaaagag     7800

tcttaacttt ctcctaattg ggagaaaaat gctttaacat tactataata atattccagg     7860

tttggagggg gtctccaggc cccatatttg ctgttaatag ttggaccttt tagaccatgt     7920

gttatttgca atcccagaat gattgcttct gctattagtt aaaaagatac tattcttttc     7980

tttctgtaca agtgcaatac tccccttgaa gtcttaaaaa ctatggtgat ttttttttct     8040

tttctgacct attcttcctt tagctaatga caaaaagaaa ctcataaaag tcatagtatg     8100

ttaaaggaca caacaagcaa agagaaaaac actccacaat caaaagatta cagaatgtgg     8160

aaaccactag tctgatctca tggtatcttt atttaagcta aatttccatg gaaattagta     8220

atcttttgct tgaaaaatgt gtcctaaagt tgaacttttt acagattgaa tcttcttaga     8280

ccctcgccca atgctctaaa ttaagaacct aatacttaat atttttattt tacttctccc     8340

cttttagaaa taaactttta aataaaagca aagcacttag ctgagtttta aacacttaca     8400

tatcacctat tggagaaatt ttttttaaaa atatttggag cagtcctgtt ttcatacaaa     8460

tttaagtaag aggtattttt cttatacata tttatatgta gtgtgctaat tttctttttt     8520

tatacctgtg tccctgtagt aaaactgctg taatataaat acatgttttg ttaaaagata     8580

acatttcttt ggcatttctt ttaaaggcag ttactgcatt tctgcatttg tacagtatgt     8640

gtcttggcca ttttagatat tctttcttta acaataccaa aggtaattag actattttaa     8700

agactaattg cttgacagtt tctagggtat tttgtgtttt agaagcaaaa aaagaaaaaa     8760

aaataggtca aaccagtaaa cctcattttt tttcaaacta ataatttggg gaaataaaaa     8820

ctattgttta aaaaagaaat atatatatat atatataaat atatatgtaa agttaaaatt     8880

ccataccttg tatgtcaggt ttgctaagtg taatgtagtt tttttaaggc tcaaatacca     8940

tacctcagaa aatgaggttt actatggaaa tactgaaaca gtctttgcag ctgtgtgaca     9000

agtcactcta ctacatactg atttggagac ctccgctaaa tagttttatc actgcagact     9060

aaaatgtggg acttgtatct tctttgtttt taatgcacac acatacatgt tctgtgcatg     9120

tatgtggtta ctgtgtatat gtgtatgagt gttgtatatg catgtgtgag tgtgtgtctg     9180

tatgtgtgta caactaaaga agctgcagaa actttgtaat actttgtgaa aaggattata     9240

ttataaaggt ttgtactgtc tgagtgcaca gctactggaa taaatttagg gaatctcagg     9300

aacaagcata taatttgtcc aagatttatt tcttctcaga agtgtaagtg cagtttttaa     9360

ttctgtatat tatttaatat tttaccaata aaataaactt ctgacataaa aagtttgcta     9420

taaaaaaaaa aaaaaaaaaa aaa                                             9443


<210>  2394
<211>  3982
<212>  DNA
<213>  homo sapiens

<400>  2394
gggagcgccg gggaggcggg cggaggcggg cggaggcggg gggcggggag cccgaggggt       60

ggaagccggc ggcggccgag cggggtcagt tctctgtagt gtttgccaat gttggagccg      120

tctgcaaagt gtccccggca agaagatgtt ctcagtgcag ctgagtcttg gtgagcagac      180

atgggaatcc gaaggcagca gtataaagaa ggctcagcag gctgttgcca ataaagcttt      240

gactgaatct acgcttccca aaccagttca gaagccaccc aaaagtaatg ttaacaataa      300

cccaggcagt ataactccaa ctgtggaact gaatgggctt gctatgaaaa ggggagagcc      360

tgccatctac aggccattag atccaaagcc attcccaaat tatagagcta attacaactt      420

tcggggcatg tacaatcaga ggtatcattg cccagtgcct aagatctttt atgttcagct      480

cactgtagga aataatgaat tttttgggga aggaaagact cgacaagctg ctagacacaa      540

tgctgcaatg aaagccctcc aagcactgca gaatgaacct attccagaaa gatctcctca      600

gaatggtgaa tcaggaaagg atgtggatga tgacaaagat gcaaataagt ctgagatcag      660

cttagtgttt gaaattgctc tgaagcgaaa tatgcctgtc agttttgagg ttattaaaga      720

aagtggacca ccacatatga aaagctttgt tactcgagtg tcagtaggag agttctctgc      780

agaaggagaa ggaaatagca aaaaactctc caagaagcgc gctgcgacca ccgtcttaca      840

ggagcttaaa aaacttccac ctcttcctgt ggtggaaaag ccaaaactat tttttaaaaa      900

acgccctaaa acaatagtaa aggccggacc agaatatggc caagggatga accctattag      960

ccgcctggcg caaattcaac aggccaaaaa ggaaaaggag ccggattatg ttttgctttc     1020

agaaagagga atgcctcgac gtcgagaatt tgtgatgcag gtgaaggtag gcaatgaagt     1080

tgctacagga acaggaccta ataaaaagat agccaaaaaa aatgctgcag aagcaatgct     1140

gttacaactt ggttataaag catccactaa tcttcaggat caacttgaga agacagggga     1200

aaacaaagga tggagtggtc caaagcctgg gtttcctgaa ccaacaaata atactccaaa     1260

aggaattctt catttgtctc ctgatgttta tcaagagatg gaagccagcc gccacaaagt     1320

aatctctggc actactctag gctatttgtc acccaaagat atgaaccaac cttcaagctc     1380

tttcttcagt atatctccca catcgaatag ttcagctaca attgccaggg aactccttat     1440

gaatggaaca tcttctacag ctgaagccat aggtttaaaa ggaagttctc ctactccccc     1500

ttgttctcca gtacaacctt caaaacaact ggaatattta gcaaggattc aaggctttca     1560

ggtatgaatt aaaagcaaaa acaaaaaaca aaacaattca ttagcctcag attcttcatc     1620

tgtatacatc acaaggctca ttcttgcctg ctagtatggc ctacatgcca cttacgtttt     1680

aagttattta ggaacacaaa ggacagacaa aaaagccata tgcacatgcc tcattttctc     1740

ttatttttga tctatctagt aattcttttg ctgcctgtct cttctccatt ttccttcttc     1800

ttttttaagc atttttcata ttcttcactg tcttctattt ggtcttgatt aggtgcatct     1860

atctcttcgc tctgtcttcc acaaacaaaa attctgcctt cagacatttg gtgttagtat     1920

ttcacactca gttctccctt tttttacata aggattgagt ttctttttat gatgatttta     1980

cctttatagc aattttgaat tttgcattct attgctagta ttgattcagg tacaccatta     2040

agatacaaca ttctagaagt ctattacctt aggagttaat taaacatgat atttgaagaa     2100

taatgaaatg ctttatagtt gtttgaggca taacaatgtg tatttgtttt actggatcat     2160

gttttgaact gactagggag ggtagcacct gcctcagata gtaccaacaa ttctgtttca     2220

ctgggtagtc taaaactagc ttatagttta acttaacttg ttgtgtatgt gaatttaggg     2280

atggaaactt tttttcccct atttattctt tgtttccttc tgggaaaaaa ccccacaaaa     2340

atcagcactc ctttatggat acattggagc ttttgaaaga attgtaaact ctaggaaggg     2400

gaaatatctg tgtcttgatt tcttagttgc cttgaaaatc atgtactgaa ctgtaaccgc     2460

taacttgact ggatgaacta gtttgcttgt gtgtagagag tgtattgctt cctcagattt     2520

cactgttttc atctcctttt ccatcttagt ctttattcct taagaccaaa aactgtaata     2580

tcctttagaa atgctctaga agatctgtat tgtgtagaat gatcatgtat ttataaatat     2640

tttacaagtt tagattataa aatgaaaaag aaggtcatgt gttttggggg gtattttgca     2700

tgttcggatt tttttttcac ttcaccgaac ccttctgatt ctttcaaact attgccaggt     2760

agttgttagt gtttctaatt ggactcttaa tatgaacttc aagaagctgt taccagttat     2820

cggctctgtc atctgaaatt ttaaccactt aatttaaagt tacaatttta gaatttgttt     2880

ttgttgtttt accttaagaa acacaataaa tcactgttta aaaaagatct caatttatat     2940

aaagtactgg aaaaaagcta agtaattttt agttctatct ataatctccg taggatgaat     3000

tagaaataaa ttgtgatgaa aagaaattaa ctgcttattt atgaatctaa tcatttagaa     3060

atgtctgaga gtaacactgc attcttatag aaacaaagca caaattgcat tcaagctctg     3120

aattgatttt ttgcttggag ctgttgttac agtagctgta attttgctac cagaatgtct     3180

taatttttta aatttgtttt tatttctaag ctcttggcaa tgacaataat tataatttta     3240

acatatcttc actgtagtca acatgtagag tctgcttccc tcattattgc attgctaagg     3300

cctttttaaa aagcttatgc ttacataata tactcttttt tatggacacg ttatatgttt     3360

ccaaatctgt gtattgtgat ttttacatac taatgaatat aaacaggtga ttttaaaata     3420

ttactgtgct tctttggttg aatgagctgg tattgatgta aaatactctg tcattgatgg     3480

accactacct gcagctaagc agtgagcaga atctccggga aatgacttag tctggccaca     3540

tgcatagccc atcttcataa tgtcgcagca gaaggttctt tgtggttaaa agttttaaag     3600

cctatttctt tataggtaac cctctcaggt atatttacct ggtagaaaaa catgtagatt     3660

gtttctatta cttaaatgtt ttaattggac tgtagtttag aaattacagg accagcttgt     3720

tacagattat acactattct gttactttta tttctgaaac ttaaaaacaa taaattcttt     3780

ttctgtgttt ctaggttaga acttttttat tttattgcac actgaacaga tactgttgct     3840

tattgaatat tgtgtaaacc cttctttggc tttccttgcc cattgcaatt tgatttaagc     3900

ctactagagc cattgtatgt gacagctata ttgtattaca aagtaaaaat atatgagtgt     3960

attgaaaaca aaaaaaaaaa aa                                              3982


<210>  2395
<211>  4411
<212>  DNA
<213>  homo sapiens

<400>  2395
acttccggtg gagggccgcc tctgagcggg cggcgggccg acggcgagcg cgggcggcgg       60

cggtgacgga ggcgccgctg ccagggggcg tgcggcagcg cggcggcggc ggcggcggcg      120

gcggcggcgg aggcggcggc ggcggcggcg gcggcggcgg ctgggcctcg agcgcccgca      180

gcccacctct cgggggcggg ctcccggcgc tagcagggct gaagagaaga tggaggagct      240

ggtggtggaa gtgcggggct ccaatggcgc tttctacaag gcatttgtaa aggatgttca      300

tgaagattca ataacagttg catttgaaaa caactggcag cctgataggc agattccatt      360

tcatgatgtc agattcccac ctcctgtagg ttataataaa gatataaatg aaagtgatga      420

agttgaggtg tattccagag caaatgaaaa agagccttgc tgttggtggt tagctaaagt      480

gaggatgata aagggtgagt tttatgtgat agaatatgca gcatgtgatg caacttacaa      540

tgaaattgtc acaattgaac gtctaagatc tgttaatccc aacaaacctg ccacaaaaga      600

tactttccat aagatcaagc tggatgtgcc agaagactta cggcaaatgt gtgccaaaga      660

ggcggcacat aaggatttta aaaaggcagt tggtgccttt tctgtaactt atgatccaga      720

aaattatcag cttgtcattt tgtccatcaa tgaagtcacc tcaaagcgag cacatatgct      780

gattgacatg cactttcgga gtctgcgcac taagttgtct ctgataatga gaaatgaaga      840

agctagtaag cagctggaga gttcaaggca gcttgcctcg agatttcatg aacagtttat      900

cgtaagagaa gatctgatgg gtctagctat tggtactcat ggtgctaata ttcagcaagc      960

tagaaaagta cctggggtca ctgctattga tctagatgaa gatacctgca catttcatat     1020

ttatggagag gatcaggatg cagtgaaaaa agctagaagc tttctcgaat ttgctgaaga     1080

tgtaatacaa gttccaagga acttagtagg caaagtaata ggaaaaaatg gaaagctgat     1140

tcaggagatt gtggacaagt caggagttgt gagggtgagg attgaggctg aaaatgagaa     1200

aaatgttcca caagaagagg aaattatgcc accaaattcc cttccttcca ataattcaag     1260

ggttggacct aatgccccag aagaaaaaaa acatttagat ataaaggaaa acagcaccca     1320

tttttctcaa cctaacagta caaaagtcca gagggtgtta gtggcttcat cagttgtagc     1380

aggggaatcc cagaaacctg aactcaaggc ttggcagggt atggtaccat ttgtttttgt     1440

gggaacaaag gacagcatcg ctaatgccac tgttcttttg gattatcacc tgaactattt     1500

aaaggaagta gaccagttgc gtttggagag attacaaatt gatgagcagt tgcgacagat     1560

tggagctagt tctagaccac caccaaatcg tacagataag gaaaaaagct atgtgactga     1620

tgatggtcaa ggaatgggtc gaggtagtag accttacaga aatagggggc acggcagacg     1680

cggtcctgga tatacttcag gaactaattc tgaagcatca aatgcttctg aaacagaatc     1740

tgaccacaga gacgaactca gtgattggtc attagctcca acagaggaag agagggagag     1800

cttcctgcgc agaggagacg gacggcggcg tggaggggga ggaagaggac aaggaggaag     1860

aggacgtgga ggaggcttca aaggaaacga cgatcactcc cgaacagata atcgtccacg     1920

taatccaaga gaggctaaag gaagaacaac agatggatcc cttcagatca gagttgactg     1980

caataatgaa aggagtgtcc acactaaaac attacagaat acctccagtg aaggtagtcg     2040

gctgcgcacg ggtaaagatc gtaaccagaa gaaagagaag ccagacagcg tggatggtca     2100

gcaaccactc gtgaatggag taccctaaac tgcataattc tgaagttata tttcctatac     2160

catttccgta attcttattc catattagaa aactttgtta ggccaaagac aaatagtagg     2220

caagatggca cagggcatga aatgaacaca aattatgcta agaatttttt attttttggt     2280

attggccata agcaacaatt ttcagatttg cacaaaaaga taccttaaaa tttgaaacat     2340

tgcttttaaa actacttagc acttcagggc agattttagt tttattttct aaagtactga     2400

gcagtgatat tctttgttaa tttggaccat tttcctgcat tgggtgatca ttcaccagta     2460

cattctcagt ttttcttaat atatagcatt tatggtaatc atattagact tctgttttca     2520

atctcgtata gaagtcttca tgaaatgcta tgtcatttca tgtcctgtgt cagtttatgt     2580

tttggtccac ttttccagta ttttagtgga ccctgaaatg tgtgtgatgt gacatttgtc     2640

attttcatta gcaaaaaaag ttgtatgatc tgtgcctttt ttatatcttg gcaggtagga     2700

atattatatt tggatgcaga gttcagggaa gataagttgg aaacactaaa tgttaaagat     2760

gtagcaaacc ctgtcaaaca ttagtacttt atagaagaat gcatgctttc catatttttt     2820

tccttacata aacatcaggt taggcagtat aaagaatagg acttgttttt gtttttgttt     2880

tgttgcactg aagtttgata aatagtgtta ttgagagaga tgtgtaattt ttctgtatag     2940

acaggagaag aaagaactat cttcatctga gagaggctaa aatgttttca gctaggaaca     3000

aatcttcctg gtcgaaagtt agtaggatat gcctgctctt tggcctgatg accaatttta     3060

acttagagct tttttttttt aattttgtct gccccaagtt ttgtgaaatt tttcatattt     3120

taatttcaag cttattttgg agagatagga aggtcatttc catgtatgca taataatcct     3180

gcaaagtaca ggtactttgt ctaagaaaca ttggaagcag gttaaatgtt ttgtaaactt     3240

tgaaatatat ggtctaatgt ttaagcagaa ttggaaaaga ctaagatcgg ttaacaaata     3300

acaacttttt tttctttttt tcttttgttt tttgaagtgt tggggtttgg ttttgttttt     3360

tgagtctttt ttttttaagt gaaatttatt gaggaaaaat atgtgaagga ccttcactct     3420

aagatgttat atttttctta aaaagtaact cctagtaggg gtaccactga atctgtacag     3480

agccgtaaaa actgaagttc tgcctctgat gtattttgtg agtttgtttc tttgaatttt     3540

cattttacag ttacttttcc ttgcatacaa acaagcatat aaaatggcaa caaactgcac     3600

atgatttcac aaatattaaa aagtctttta aaaagtattg ccaaacatta atgttgattt     3660

ctagttattt attctgggaa tgtatagtat ttgaaaacag aaattggtac cttgcacaca     3720

tcatctgtaa gctgtttggt tttaaaatac tgtagataat taaccaaggt agaatgacct     3780

tgtaatgtaa ctgctcttgg gcaatattct ctgtacatat tagcgacaac agattggatt     3840

ttatgttgac atttgtttgg ttatagtgca atatattttg tatgcaagca gtttcaataa     3900

agtttgatct tcctctgcta aattgatgtt gatgcaatcc ttacaaatga ttgcttttaa     3960

aattttaagc taggaaaaga aatctataga aagtgttctg ttacaaaatg taactgttac     4020

cattggaaat ttcacgtcat aggaagttag cctttatcta ccaactttca agaacttgtt     4080

taataaagcg aaaaactcaa ccaaatggta caaaaccaca gtgtaccatt aaaatatgca     4140

ctaagtctct tttttacaaa ggctgtattc agcaaggcgc taacttgctt aaatgtgaat     4200

tactaacttc taaaactgta ctttgattca catgttttca aatggagttg gagttcattc     4260

atattacaat atttgtgtgc taaacgtgta tgtttttcag ttcaaagtca tgatgttttt     4320

aaaatcttat taaagtttca aaaatctgaa gattgtttat ctagatgtaa atttttatta     4380

aaaagttgca cttatgaaaa agcaaaaaat t                                    4411


<210>  2396
<211>  2748
<212>  DNA
<213>  homo sapiens

<400>  2396
gcggccgccg ggcgccggag ccgcgtcccc ctgcgccgcc ccgggcctgc cggccggagg       60

agccaccata caccccgggt cgccgagcgc ctggccgccc cgcgcccgcg ccgcgctccg      120

cctgtggctg ggctgcgtct gcttcgcgct ggtgcaggcg gacagtccct cagccccagt      180

gaacgtcacc gtcaggcacc tcaaggccaa ctctgcagtg gtgagctggg atgttctgga      240

ggatgaggtt gtcatcggat ttgccatctc ccagcagaag aaggatgtgc ggatgctgcg      300

cttcatccag gaggtgaaca ccaccacccg ctcatgtgcc ctctgggacc tggaggagga      360

tacggagtac atagtccacg tgcaggccat ctccattcag ggccagagcc cagccagcga      420

gcctgtgctc ttcaagaccc cgcgtgaggc tgagaagatg gcctccaaga acaaagatga      480

ggtaaccatg aaagagatgg ggaggaacca acagctgcgg acaggcgagg tgctgatcat      540

cgtcgtggtc ctgttcatgt gggcaggtgt cattgccctc ttctgccgcc agtatgacat      600

catcaaggac aatgaaccca ataacaacaa ggaaaaaacc aagagtgcat cagaaaccag      660

cacaccagag caccagggcg gggggcttct ccgcagcaag atatgaaaac cttttcagtg      720

cttgccctca gcagctaaga agacagacag tagagaatgt gagaggatct catggttctg      780

atgatgatta tccaacaaac atctggccct ctctacatct cttccctcca tctccttgta      840

ccctctggct tactgtcctc tctctggcgc actttcctga agcctcttat taactcccat      900

ctccagaagc acctcaacaa tgtcagtggc tgaggctgca ctcagaggga tgactgctgg      960

gggtagactg ggtgccaggg gccatgggcc caggacccag tcttggccat tcagttgagt     1020

gaggctgaag gctgggtttg aaaaggcaaa aagacaagac atccaggcag ggcttctctt     1080

ttctttccac aagggacaag agcttggctt atttaggcta cagccctgct gctgctccct     1140

tccttcttct gtcctgtttc cagccttgca agaaggctat tcacaattag gcctggctgc     1200

ttctctcatt tttttcctcc cagtttccaa acaagccctc agtgaacatc attgaagcgt     1260

gactgcctgt ctgcagggag aaggattcca tttttcttct cagctggtcc ccaggcccac     1320

gggcacaggg agagggacaa ctgcagcagt ggggaggagg cacagctagc tgcacagttc     1380

tctcttctcc ttgtcctagt cagatgaagg aggctgcact acaaacccaa attctgcaaa     1440

aaaataaaaa taagccacaa aactaaaagg cctggcccca ttctggaaaa ggcaaagctg     1500

catgagacac agccttctgc ctcctcgcct ctcctggact ggcttcctct ttgagaaaat     1560

gcacaaagcc ctgggagatg acaagcacaa ggactgactc aagctgtgtc tttcagacca     1620

aggaacatca gagaagctgt ggggctgcct gccaggcagg atcatggctg ccatcaagcc     1680

ttttctggat ccagccatca aggacatgtt tgtggtgtga tgcacacttt tgcaagcgtg     1740

taagatgtta cctggtttgt ctcttttgga aaacaaaaat cagaaggctg cattctagag     1800

ggcagagaaa ttcccccgaa gactgagctg gttgcctgca tcctctatct tctttgaccc     1860

ttatgactga aagatcatca gtttggaagg tactggtcca atttatttag gaagtatctc     1920

ttggagtttc agaaatgcta gcttggacaa ctgaaaagtc acatcacagc tggcattctg     1980

ggggctacca aaacacccct tctggagtag aagctgctgg aaggcaggcc tgagccattc     2040

accacggaca ggaagagcag ctctggctat caccactggc ctctggggtc ttcatatctt     2100

gccatctcat ccagggttcc atgaaagtta cccagggtcc tcatgtcctt ccttagagcc     2160

tgagtggtgt gaggtgacag gtctctctct ccactgcccc tttctggttt aaaaaaatgg     2220

tgcttgatga gggaaggtag actcttccct aggactgacg agttacggct gccagatgcc     2280

tgcatgggaa gaggtggaca tctgcatctt ccattggtgg tcaaggatgg gtgtgggaga     2340

accacaccta gtgcaagcct ggtactcagt aaatatttgt tgaaatgaat gataagagca     2400

ttggtcccca agccagagag ccagaagcca tcacccaatg accgcccctt ccttccggtc     2460

tacaagagct ctcaaggctg ggtctgccac cactctgctt tgcccaagtg tgacagcact     2520

ggggaggaga gacaggataa agggcagatg tcagcaatac taagggcttc ctcatgggag     2580

ggcatgaggc tccactcatt gtcttgtgac ttccatccct gctgaatggg gctgcaaggc     2640

caaggctcct taggggagag gtccttacct ctgatccact tagagcaata accacttttt     2700

aaatgtaaaa taaaaagaca aatgaaaagg caaaaaaaaa aaaaaaaa                  2748


<210>  2397
<211>  7029
<212>  DNA
<213>  homo sapiens

<400>  2397
agcgcaggtc ccgacagagg tcgccgggtg gtggcgtcag ctgcggcgcc ctccgcgtgg       60

aaattagccg gttgcccggg caaatcaggg aggaagggag ggagctgaac acggaagtgg      120

tggcggcgcc cagggaaccg gcggaggcga tgaccgtgac ggctgggttg ggaccggaac      180

gccgaagcgg ggttgggggt ggcagaaaag catctgcttt gtaagaccta cacgaggtgc      240

aggagtggtt gggcctcccc tctccactta agcaagcgcc cagactgatg gcgatggtga      300

tggcagcagt tactcgcaca accccagtta agctgcgctc cgggaggagt tcatctgttg      360

tctgctctcc agtgacttcc gtttgtggag cctaagtgtt tctacagaat ccaactcaaa      420

tatcaaggac tatgatcaga atgctttcaa ggagtttttg ggcacatgat ggcagataca      480

tccagaaagt gcccagaaga aacttcctgc tggaaaaaat gaaaaagcag tatttataac      540

attagaatct ggataatttg ttaacatggc agaaaataat gaaaatatta gtaaaaatgt      600

agatgtaagg cccaaaacta gtcggagcag aagtgccgac agaaaagacg gttatgtgtg      660

gagtggaaag aagttatctt ggtcaaaaaa gagtgagagt tattcagatg ctgagacagt      720

gaatggtata gagaaaaccg aagtgtcttt aaggaaccaa gaaaggaagc acagctgttc      780

atccattgag ttggacttag atcattcctg tgggcatcga tttttaggcc gatctcttaa      840

acagaaactg caagatgccg tggggcagtg ttttccaata aagaattgta gtagtcggca      900

ctcttcaggg cttccgtcta aaaggaaaat tcatatcagt gaactcatgt tagataagtg      960

tcctttccca cctcgatcag atttagcctt taggtggcat tttattaaac gacacactgc     1020

tcctataaat tccaaatcag atgaatgggt aagcacagac ttgtctcaga ctgaattgag     1080

ggatggtcag ctaaaacgaa gaaatatgga agaaaatata aactgtttct cacataccaa     1140

tgttcagccc tgtgtcataa ccaccgacaa tgctttgtgt agagaaggtc ctatgactgg     1200

ctctgtgatg aacctggttt caaataacag tatagaagat agtgatatgg attccgatga     1260

tgaaattcta acactttgca caagttccag aaaaagaaac aaacccaaat gggatttgga     1320

tgatgaaatc ctgcagttgg aaacacctcc taaataccac acgcagattg attatgtcca     1380

ctgtcttgta ccagacctcc ttcagatcaa taacaaccca tgttactggg gagtgatgga     1440

taaatacgca gccgaagcac tactggaagg aaaaccagag ggtacctttt tacttcgaga     1500

ctcagcacag gaagactatt tattctctgt tagttttaga cgctatagtc gttctcttca     1560

tgctagaatt gaacagtgga atcacaactt tagctttgat gcacatgacc cctgtgtctt     1620

ccattctcct gacattactg ggctcctaga acattataag gacccaagcg cctgtatgtt     1680

ctttgaacca cttctatcca ctcccttaat tcggactttc cctttttccc tgcagcatat     1740

atgcagaaca gttatttgta actgtacaac ttatgatggc atcgatgccc ttccaattcc     1800

ttcttctatg aaattatatc tgaaggaata tcattataaa tcaaaagtta gagtactcag     1860

gattgatgca ccagaacagc aatgctagta acaggatggg aacatgggaa tgataatata     1920

tattttttct tttaatattt tatttttctt tttatgccac tttggatttt tctacaaagg     1980

cagtggtgtc caaaataaaa tctctgccct aaattttact aataaatcca tttttctagt     2040

gatacacaaa ttgtttaagg ttatacactc gagcttaaat agatattttt aaccaggtgt     2100

ttggtttttg tttttaccgt gtaggttgta tacttacatt ttttctttcc ttaatttata     2160

catgatcctt tttccttaat ttatacatga tccaggcaca tttgaaattt ggtaggcatt     2220

gcaaacacat ttgaatattg tgtatttcat actattcttt aaaagtaatc ttatgtcctt     2280

tcctacatgt aaaatatttt gttaatctat gccattagta gtattatata taaaatatag     2340

ttccccgtcc cccttttcat tgagtttgat attcttcagt aaagctgaat gttgtaattc     2400

accattcata ctaatgttat tgacttttgt aacttactaa tagggatgtt aaaagtaaca     2460

aaaccaagtc aaacttggtg tatttttatt ttaaatatta actctaaagc aggattacta     2520

aatttgatta atctggtcaa tgagaatcaa atggaaacat atcattctgg aggtgcactt     2580

actcttctac aatgtggccg gatcatttgt cattcctgaa taggtctttc tctcaacctg     2640

caagagctaa accatcttca aaacataaat cttgttcctt tctcattgga agctttgaaa     2700

ataatgataa cactattagt agctagtagt tactaaagtg ctaaagtaat tgtggggttt     2760

ttctgtatta gcttatgaac tgttgcttct acttagccct tttatagaaa ctctgagctg     2820

ttactttggg gaaattccac aatgtattag cagccacaaa tttccactgg taaccaaaga     2880

gtacctaagt agtttttcat tattttaagt tgaatttgaa taaagattcc agaaataaac     2940

atggagctca gtattcagga agcttaatac tgtttttgat ctacaagatc caaataatta     3000

tccctatctt cagaattaac ttagtctgta atgtggcttc aaaaaaagaa agccttttga     3060

cagctacatg acttacacca tacagaacag tactggacaa aaggggtgat attttaaatt     3120

tactatccca gaaacagggc aacgttttta gaaacatctt tagcccaaag taactagtaa     3180

aaataaatgg agtggtatcc tatcttcttt ttttaaggaa tcaatgaata ataaatgtag     3240

atagacaatt ttcttctggt gagctgtcta accctttgta cacattgaca tttttaatat     3300

cgtaactgat ttcttgatgc tagtttagct atattaggaa actgcttcta cctagattga     3360

aagaaatttg actcataaac ttccaagtta gaacaaatat ttcttcatta ttgttgcttt     3420

tatgtgagta gcatttccct atcttgcagt tctgttaaca tgaaaatggc atttttccat     3480

aatagcttta aaataatttt ttagtaatta ttacaaaatt aaggaaaatc tctattaccg     3540

ttatctttta gcattttttt tttcctcagt gatctcaaga ttgtcttagt ctcaatgaga     3600

tgtagctaca aaaatggcac ctcttagcag tgatgaggct caggatatcg gatatcataa     3660

caccaatgtc aggataaata tctcttctaa agacgatatt taccttttac aaggttagaa     3720

aagtctcata ctacctcatc tttattgtgg cgcttttgta gatcactgag aagcttatct     3780

tattaaccaa tataccactt cctaaatatc catctttggt gaaagaaaat agtgtggtaa     3840

gagtacccat gattatagtt ttttatcaga atttgataag attttctgtt tctgtgaaac     3900

aattatttta aatatttttc ttttaaaaat aactttttat cagtacagaa aaacctaagg     3960

gatgactagc ttacaaatat tctgttaagg ggtagtttta taaagaaaaa tgatatatag     4020

ttatgttgtc ttttatagtg ttaaaattag tatttatatg aaagtcaaga tctaagtacc     4080

ttttcatata attcaaactg attgcttgtg atatgttttc tctggctttt ttattttttc     4140

aacttcaagg tattaacagc tgttaacact taaaaagtac tgccacatat gtagccttga     4200

agtagttgat ctaataaatg agagcaggga ggagattcat tgactctgaa atgattttta     4260

tttttccttt ggtatttgct acagtgaaaa gaagtttgga aagtagatac ataaagactt     4320

gagaagggaa ttgtttaagg gaaaagaaaa gagtaataat tttttttaaa acattaagga     4380

attggaattc agaaaggtta cccccttcct ctgtgtcttt gtaaggatac atttggaaga     4440

acatacagta ttcagaaact aacctatata aaatgtaaac aatatattga ttgcactata     4500

taaatgagta aattttgaga ggaacaatgt gggaatgtat aaatttgtct aaaattttat     4560

aactgttgaa caaagggaag atttgaacag tgtaaattcc agagttgaga aagcatttag     4620

catggtggaa atgtggagag cttattggtg agagaggatg gagctaagag aaataagatc     4680

aaatattaaa attaggaatt taggcattac ctcagggaaa agccttgaca gtgaaaagaa     4740

actacttaat cgctaatagc tagtctggac cagacactta actgcgcttt gggaatcatc     4800

ctgggctaat caggaaataa acttgacttt tctatttttc tctgaagctt tacaggacat     4860

actcccactc ccattttttt ctaagcctac agcatcttga ttcatagtat aattcctgaa     4920

gtatgctgaa tggacttttt aaggttcctt tagcattttt gtatagagtt atatgtgatc     4980

tttctataac catgccattc acttaaataa ttcatgaagg gaatggttta atttaaagga     5040

agacctaata ggaagaagat taaaggaagc ttttagtcag cctgtggcta gatttattga     5100

tttggtgatc aaacctgtgc tatttcctga atttcagcta atggccaact gtggtcaaag     5160

aatggctttc agttaaagtt ttgacttctt attataaata atataaagaa tgtctcagta     5220

attagaaatc ccttaataag tagaacaaat gtggcaagta ggactcctat cggtatacaa     5280

attccatttc tttttataag aaaaacacat aaaccattat catttattca tgagccaaag     5340

ccattaagaa gataaatcca gttatcagct tcctgtctct gaagtttgga tcattttata     5400

gatccacgca atagagagct tccttcctat gaaacaaaaa ccttgagatc tctttttttt     5460

tgagacagag tctcgctgtt gtcagcccag gctggagtgc aatggcgcaa tctcggttca     5520

ctgcaacctc tgccttccag gttccagcaa ttctcctacc tcagctccca agtagctgag     5580

atgacaggcg tgtgccacca cgcccagcta atttttgtat ttttagtagc gatggtgttt     5640

cactacattg gccaggctgg tctcgaactc ctgacctcag gtgaccaccc gcctcagcct     5700

cccaaagtgc tgggattaca ggcatgagcc actgtgcccg gccaagatct aactcacgct     5760

tacttttcat taaaatattt cttgtcgctt ttagctattg tcagaatcca ataaacagct     5820

tacgcattca ttttggtaaa gcaaatttca caggaaaata gacaaaatta taagagattc     5880

ctggagacaa cacaaggaaa acaatgttta aaagcaaaat agcctgtgta atgttaggta     5940

atgtaatgcc caagtgaata aaagattttt cgtcaagcaa actactgttt ctactttggg     6000

ggaaaaaagt cagttttaca tttgtaattt aaggaaagaa cagaaagcac aaaggttttt     6060

cttttcttta ttaatggcct actagaaatg agcagtgcaa gagtctacct gtactattct     6120

aatacagtaa gatattggac acaaaatgga ggtaactttt taaaatagat tggcttggaa     6180

gttgaaatgt agattaatgg atataaccca atagaaaggg attttcaaat aaaaccaaag     6240

tctatttttt tatttacttt ctaattttga acagatgact cagtcctaaa tctttgcctt     6300

tatttcctat aaaatgtagg tgatacttgt aactcgactt cctggagtta attcttcagc     6360

aagaggtgac cctgggagcg tactttaaaa taattgctgt acagccattg agtactaaca     6420

tgatgatagg ttttcaaaat atctttgtag tggatgctgc ataattacat tcacttctct     6480

tagactgtaa aagactttct tgacttgttt taacagtaga gatagcagta caatttgaat     6540

ttatggttta ggctctgcaa ttagaggaac aattgcagtt tcctcctacc cttcatatgg     6600

tctgtgtaaa actgatgttt gcttaactta ttttaaaagt tgattacgtt ttcagaaaat     6660

aaagataatc acttttgcca tggttataat caaatctaag ctttcagact tgagagccat     6720

ggtgtaaaac tcaaggaggt ttatttaaat tatgctgact ttgctagaat tggataaatt     6780

ctgtataagc caagtatgag ttcacatgta ctcgaatata cagttttcac aaagctatta     6840

ctctcatcag tcaggcttgt atgatctatt ccttaccaca aaagaagtag acaattgcca     6900

cttttatttc taatccttaa gttgaatgtt tcttcttgga tgtaagttca aataaattga     6960

tctggataaa ttttcatttc tacttaatta aaacttccta tgtaaaatcc aaaaaaaaaa     7020

aaaaaaaaa                                                             7029


<210>  2398
<211>  3216
<212>  DNA
<213>  homo sapiens

<400>  2398
taattcctga ggggtggttg ctgcttttgc tacatgactt gccagcgccc gagcctgcgg       60

tccaactgcg ctgctgccgg agcgctcagt gccgccgctg ccgcccgcgc cccccgcgcc      120

ccgttcggca cccaccggtc gccgccgccc gccgcgccgc tgtcccgctc ccgcgccgcc      180

gccgccgttt ccccccgacg actgggtgat gctggacatg ggagatagga aagaggtgaa      240

aatgatcccc aagtcctcgt tcagcatcaa cagcctggtg cccgaggcgg tccagaacga      300

caaccaccac gcgagccacg gccaccacaa cagccaccac ccccagcacc accaccacca      360

ccaccaccat caccaccacc cgccgccgcc cgccccgcaa ccgccgccgc cgccgcagca      420

gcagcagccg ccgccgccgc cgcccccggc accgcagccc ccccagacgc ggggcgcccc      480

ggccgccgac gacgacaagg gcccccagca gctgctgctc ccgccgccgc caccgccacc      540

accggccgcc gccctggacg gggctaaagc ggacgggctg ggcggcaagg gcgagccggg      600

cggcgggccg ggggagctgg cgcccgtcgg gccggacgag aaggagaagg gcgccggcgc      660

cgggggggag gagaagaagg gggcgggcga gggcggcaag gacggggagg ggggcaagga      720

gggcgagaag aagaacggca agtacgagaa gccgccgttc agctacaacg cgctcatcat      780

gatggccatc cggcagagcc ccgagaagcg gctcacgctc aacggcatct acgagttcat      840

catgaagaac ttcccttact accgcgagaa caagcagggc tggcagaact ccatccgcca      900

caatctgtcc ctcaacaagt gcttcgtgaa ggtgccgcgc cactacgacg acccgggcaa      960

gggcaactac tggatgctgg acccgtcgag cgacgacgtg ttcatcggcg gcaccacggg     1020

caagctgcgg cgccgctcca ccacctcgcg ggccaagctg gccttcaagc gcggtgcgcg     1080

cctcacctcc accggcctca ccttcatgga ccgcgccggc tccctctact ggcccatgtc     1140

gcccttcctg tccctgcacc acccccgcgc cagcagcact ttgagttaca acggcaccac     1200

gtcggcctac cccagccacc ccatgcccta cagctccgtg ttgactcaga actcgctggg     1260

caacaaccac tccttctcca ccgccaacgg cctgagcgtg gaccggctgg tcaacgggga     1320

gatcccgtac gccacgcacc acctcacggc cgccgcgcta gccgcctcgg tgccctgcgg     1380

cctgtcggtg ccctgctctg ggacctactc cctcaacccc tgctccgtca acctgctcgc     1440

gggccagacc agttactttt tcccccacgt cccgcacccg tcaatgactt cgcagagcag     1500

cacgtccatg agcgccaggg ccgcgtcctc ctccacgtcg ccgcaggccc cctcgaccct     1560

gccctgtgag tctttaagac cctctttgcc aagttttacg acgggactgt ctgggggact     1620

gtctgattat ttcacacatc aaaatcaggg gtcttcttcc aaccctttaa tacattaaca     1680

tccctgggac cagactgtaa gtgaacgttt tacacacatt tgcattgtaa atgataatta     1740

aaaaaataag tccaggtatt ttttattaag cccccccctc ccatttctgt acgtttgttc     1800

agtctctagg gttgtttatt attctaacaa ggtgtggagt gtcagcgagg tgcaatgtgg     1860

ggagaataca ttgtagaata taaggtttgg aagtcaaatt atagtagaat gtgtatctaa     1920

atagtgactg ctttgccatt tcattcaaac ctgacaagtc tatctctaag agccgccaga     1980

tttccatgtg tgcagtatta taagttatca tggaactata tggtggacgc agaccttgag     2040

aacaacctaa attatgggga gaattttaaa atgttaaact gtaatttgta tttaaaaagc     2100

attcgtagta aaggtgccca agaaattatt ttggccattt attgttttgt ccttttcttt     2160

aaagaactgt ttttttttct tttgtttact tttagaccaa agattgggtt ctagaaaatg     2220

cacttggtat actaagtatt aaaacaaaca aaaaggaaag ttgtttcagt tggcaacact     2280

gcccattcaa ttgaatcaga aggggacaaa attaacgatt gccttcagtt tgtgttgtgt     2340

atattttgat gtatgtggtc actaacaggt cacttttatt ttttctaaat gtagtgaaat     2400

gttaatacct attgtactta taggtaaacc ttgcaaatat gtaacctgtg ttgcgcaaat     2460

gccgcataaa tttgagtgat tgttaatgtt gtcttaaaat ttcttgattg tgatactgtg     2520

gtcatatgcc cgtgtttgtc acttacaaaa atgtttacta tgaacacaca gaaataaaaa     2580

ataggctaaa ttcatatata tcttgatact tttgtctctt ttattaagta gagctaattt     2640

tttaaagacc aatcaactta tagggaattc aaaggctttt tcagccaaac taaaatttaa     2700

actgctcctt taatttgaac tgactctaaa aatgaaaata gtatttttcc ctttgtgaac     2760

aaattttaca aggagcagcc tatttaataa acactagctt taaacaaagt ataggctttt     2820

cagctgatac ctgtaagttt ctgtggatat acagcaaaaa gagatataat ttaattttct     2880

gtgcatagct ctttaccctg tgtttatttc caaatccatt aatagaatgc catttatata     2940

ttttgtttca ggtatattgt taatagagct tggcaaatta taaataaata tatgtatatg     3000

gttagataga agtgactata atgcacacat atgtaatata tatagacaca cagagccctt     3060

cagttcaggt acaatttgcg ctatgaatgc tgcaaacatt tttgtttaaa tatttgtatt     3120

tatactttct aagtcagcat ttatttttgt ggctgtttac ccacaatgaa agagttctaa     3180

taaagatgtg ctgaagttgc aatataaaaa aaaaaa                               3216


<210>  2399
<211>  5499
<212>  DNA
<213>  homo sapiens

<400>  2399
tctgcccgcc ttctggctcc ccgggagccc agactggtcg gagcccgagc ggtggcagcg       60

cggggagccc cacgcgccga agggagcgga cccgacagga cggccctaga ggaggtgctg      120

ccgccacagt agcagggacc ggagtctcga gccgcggcct cccggaccgt gctgcccagg      180

ccagctcagg gacagccggg agtacgaaag ccccaccctc tggggcaccc cgggagcgga      240

ggcgggagcg gggacgcgag caacctctcc ccctgttgga gagaaaagac ccttaccact      300

cgggtgaggg aaagaagaga cccctggagg ggacgcctct ctcctgccta gaggcgagga      360

agacccctgt actggccggg gaggagaccc ccagaagtgg aaagaaggga gctttccgta      420

gggaagcaga gtgagaccac cctagcgcgc ccccgcccct ccaaacacac actctcaaca      480

gttcaggact ttggaggcaa agagagacgg ggctgtgcct gtggagtagg caccctcggc      540

ccaccactat tcacaggaga caggagtcct tacgttcaga agccactcca gggaaagaag      600

aggaatcggc tttcagcctt ctggagaggg gaagacctcc ccctcaactt cctcgtgcct      660

agacagtgga acggggtgga gcccctccgc tcctatctcc agcagacaga aagagccctc      720

cacctcagaa agatccagtt tgggggggag gggaactccc ccaaggggga ggagacaact      780

cctggttggg agaggctcct cccctcctcc cccgggtaac aagcagggtg tggggggtgt      840

gccaccttcc ccaagtagga cctccttctc ctccccctcc ccctcctcca accttgactc      900

ctcatcctca ggggacccag ttcccctcac caacttggga ggctcagcct cgtccaggaa      960

gagccactga ggatgagagc cgtcacctgc ctctgaagag gggaatccct ccaaccccaa     1020

actccagtac caggtggttc cctccctttg ccggaggaac cttggagaca gaacccagaa     1080

gtaccatggc ttctgaccta gagagtagcc tcacctccat agactggctc ccccagctga     1140

ccctccgagc taccattgag aagcttggaa gtgcctccca ggctgggcct cccgggagca     1200

gccgcaagtg ttcaccaggg tcacccacag atcctaatgc caccctgagc aaagacgagg     1260

cagcagtgca ccaggacggc aagccacgat acagctatgc cactctcatc acctatgcca     1320

tcaactcctc tccagccaag aagatgaccc tcagcgagat ttaccgctgg atctgtgata     1380

acttccccta ttacaagaat gctggcattg gttggaagaa ttcaatacgg cacaaccttt     1440

ctctcaacaa gtgtttccgg aaggtgccca gacctcggga tgaccctggg aagggttcct     1500

attggacaat tgacacctgc cctgacattt cccgaaagag aagacaccct ccagatgatg     1560

atctgtccca agactcacca gaacaggagg caagcaagag cccacgggga ggcgttgcag     1620

ggagtggaga agcctcactg cctcctgagg ggaatccgca gatgtcactt cagagcccca     1680

catctatagc cagctacagc cagggcacag gatctgtgga tggtggagca gtggcagcag     1740

gggcttcagg ccgagaaagt gctgagggtc cccctcccct ctataacacc aaccatgact     1800

ttaaattctc ctactcagag atcaactttc aggatctaag ctggtccttc cgcaacctct     1860

ataagtccat gctggagaag tcctcttcct cctctcagca cggcttttct tctctcctgg     1920

gggacatccc accctcgaac aactactaca tgtatcagca gcagcagcca ccgccacctc     1980

aacagcagca gcagcagcag cagccgccac agccacctcc ccagcagtcc cagccacagc     2040

agcagcaggc acctgcccag ggcccctcag ctgtaggggg tgctcctcca ctgcacaccc     2100

caagcacaga tggttgtacc ccaccagggg gaaagcaagc tggggcggaa ggctatgggc     2160

ctccccctgt aatggccatg catccacccc cgctgcagca tggaggctac caccctcatc     2220

agcaccatcc ccactcccac cctgcccagc agccaccacc tccacagcca caggcacaag     2280

gccaggctcc catcaacaac actggctttg cctttccttc tgactggtgc tctaatattg     2340

actctttaaa ggaaagcttc aagatggtga atcggctcaa ttggtccagc attgagcagt     2400

cacaattctc agaactgatg gagagtctac gacaggcaga gcagaagaac tggaccctcg     2460

accagcatca cattgccaat ctgtgtgact ccctcaacca cttccttact cagactggtc     2520

acgtgccccc tcaagggggt acccaccgcc caccagcccc tgcccgtatt gctgactcct     2580

gtgccctcac cagtggcaaa caggagtcag ccatgagcca agtgaactct tatgggcacc     2640

cacaagctcc ccacctctac cctggcccat caccaatgta cccaatcccc acccaggact     2700

cagcaggata caatcgccca gcacaccata tggtccctcg gccatcagtg ccacctcctg     2760

gtgccaatga ggagatccct gatgacttcg actgggactt gatcacttag tgcatcacag     2820

agtgtggaca tcagcccagg gccgcgtggt gaaatctggc agtggggaaa gagcaacccc     2880

agcccgtccc ttccccccgt ctgtatatag acatatatcc tctttttgtt ctttctctgt     2940

cagagaagcc actgcaagat gctgccgaag ataaccctct ctttcctgcc tcattcttct     3000

ctcttccttc ctgttttttc ctagttcttt tattattatt cttatattat tattattatt     3060

attggttata tactgtccat agtctcctgt ccctacatca tggatcatgt ccaccttttg     3120

ctaatttaaa atcatcaggc tggaagatga agccatgata gctacagaga aaggttttag     3180

actccagttt acctttctct tggagaaact caatgctaat cccacctttt ggccctaaat     3240

tgttttttgt tcccatcagt ttcaggccag gactggagag gccacattac caagtagaaa     3300

gggtctgaaa cattacttgg cagccaagaa tttggaggtt ttaaaatggt gctaattctg     3360

tcctctgagg tcttccttgt ccctttatac cttcaatcct tacttctgcc agtctgtatt     3420

tcctatcaag ggtgaaagtg atgatggtgg tgcaggaggg tgacaataaa atcctagtgg     3480

aattggagac cattggaagg gatggaatat aagtcagtgt gaaactgagt atacactgcc     3540

atgttacatc agtgtccatt ggcttgtttt gagcctgttc tctaagaaga taggattggt     3600

tttagcccaa actctgcttc tatggtaggg catgaggaca actattcagc atggttttag     3660

cttcttggag atgattccaa cttaactatt ttggcttttt aaacataatt ttctctgaaa     3720

attaattgtg gctcttattt gcatttacga atgatcttcc catccctttt tcccattcag     3780

caaatattag tttgtcctcc tttaattgtt tgcccaaatc ttccacccat cttttttctt     3840

ccctcatttt ctgggattct caagaaagaa aaagtaaccc attatcactc tgagtttcgt     3900

cgtgccctga gacatgatgg gaatctcatt cccacctctc atagcagagc caaaccttta     3960

gtgttggtgg taggaggatg gggagaggaa aaaagagctg gcaaagaaat ggatagggaa     4020

tattttagtt ctttaaatat ataggcagat gcttctcttg gaatccagat catctggctg     4080

aagcttttgc aagtaggctt tgaggggtga aggagattgg tggaggagag taaataatct     4140

agaggcaaga gttcagtgag ggccaagggg gacccccaga aaaaggtatg gagctaactc     4200

atctctttta caaggggtgg ccatgactta ctgttgcaaa gtactcagtg tatatttaat     4260

gttgattgtt gaattttagt tacgagaggg aagaacaatt ttacttctgt ccttatttca     4320

cttgctgaaa agctgtggga caaaatgtat ggaatagaca aggccacttt ctttgtgatt     4380

tctgcttttc atgcatatta ttttatttac ccataatttc caagaggttt ggcgttccgc     4440

tctcctgctt ttttctttca tccacccctt tccttttttt ggaagggggt tatatatgag     4500

agttcattga agaagtccag tgaggctgaa gtaaaggggc aagatagggc agttaactaa     4560

agagcacttt atttctttga agcctttcta agaaagaaat gggggtgcga gtggcttgaa     4620

tctcccatga tgttggaggg cacttagtgg ggttgaagta tgacataata tttcccattg     4680

gggaaaggag aatttctctt agagggtggc aaaatgcctt tgcccagtgt ccctatttta     4740

ggcatctttt ccttccttat tccttccagt cagggtgtgt cctatacaaa acttcccatc     4800

agttctcctc aatattcccc atttgtaaat gatcacttct cttttctaaa cccttttcct     4860

gttcagatcc atacaggatt tgcaagggta ggatcataca tgcaaatgcc ccttgttcat     4920

ctgtgtcttc tgcaaactag tctcatgaag aattctggcg tgcagccagg gtagctgaag     4980

tttgggtctg ggactggaga ttggccatta ggcctcctga gattccagct cccttccacc     5040

aagcccagtc ttgctacgtg gcacagggca aacctgactc cctttgggcc tcagtttccc     5100

ctccccttca tgaaatgaaa agaatactac tttttcttgt tggtctagca ttgctggaca     5160

caaagtgtag tcattattgt tgtattgggt gatgtgtgca aaactgcaga agctcactgc     5220

ctataagagg aaataagaga gaaagtggag gagagggaca aaaggagtaa ttatttggta     5280

tagatccacc catcccaacc tttctctcct cagtccctgc tcctcatgtt tctggtttgg     5340

tgagtccttt gtgccaccac ccataatgct ttgcattgct gcatcctggg aagggggtat     5400

atggtctcac aagttgttgt cattgttttt ttgcatgctt tcttaataaa aaaaaaaaaa     5460

gaatgtttac agttttatct taaaaaaaaa aaaaaaaaa                            5499


<210>  2400
<211>  5499
<212>  DNA
<213>  homo sapiens

<400>  2400
tctgcccgcc ttctggctcc ccgggagccc agactggtcg gagcccgagc ggtggcagcg       60

cggggagccc cacgcgccga agggagcgga cccgacagga cggccctaga ggaggtgctg      120

ccgccacagt agcagggacc ggagtctcga gccgcggcct cccggaccgt gctgcccagg      180

ccagctcagg gacagccggg agtacgaaag ccccaccctc tggggcaccc cgggagcgga      240

ggcgggagcg gggacgcgag caacctctcc ccctgttgga gagaaaagac ccttaccact      300

cgggtgaggg aaagaagaga cccctggagg ggacgcctct ctcctgccta gaggcgagga      360

agacccctgt actggccggg gaggagaccc ccagaagtgg aaagaaggga gctttccgta      420

gggaagcaga gtgagaccac cctagcgcgc ccccgcccct ccaaacacac actctcaaca      480

gttcaggact ttggaggcaa agagagacgg ggctgtgcct gtggagtagg caccctcggc      540

ccaccactat tcacaggaga caggagtcct tacgttcaga agccactcca gggaaagaag      600

aggaatcggc tttcagcctt ctggagaggg gaagacctcc ccctcaactt cctcgtgcct      660

agacagtgga acggggtgga gcccctccgc tcctatctcc agcagacaga aagagccctc      720

cacctcagaa agatccagtt tgggggggag gggaactccc ccaaggggga ggagacaact      780

cctggttggg agaggctcct cccctcctcc cccgggtaac aagcagggtg tggggggtgt      840

gccaccttcc ccaagtagga cctccttctc ctccccctcc ccctcctcca accttgactc      900

ctcatcctca ggggacccag ttcccctcac caacttggga ggctcagcct cgtccaggaa      960

gagccactga ggatgagagc cgtcacctgc ctctgaagag gggaatccct ccaaccccaa     1020

actccagtac caggtggttc cctccctttg ccggaggaac cttggagaca gaacccagaa     1080

gtaccatggc ttctgaccta gagagtagcc tcacctccat agactggctc ccccagctga     1140

ccctccgagc taccattgag aagcttggaa gtgcctccca ggctgggcct cccgggagca     1200

gccgcaagtg ttcaccaggg tcacccacag atcctaatgc caccctgagc aaagacgagg     1260

cagcagtgca ccaggacggc aagccacgat acagctatgc cactctcatc acctatgcca     1320

tcaactcctc tccagccaag aagatgaccc tcagcgagat ttaccgctgg atctgtgata     1380

acttccccta ttacaagaat gctggcattg gttggaagaa ttcaatacgg cacaaccttt     1440

ctctcaacaa gtgtttccgg aaggtgccca gacctcggga tgaccctggg aagggttcct     1500

attggacaat tgacacctgc cctgacattt cccgaaagag aagacaccct ccagatgatg     1560

atctgtccca agactcacca gaacaggagg caagcaagag cccacgggga ggcgttgcag     1620

ggagtggaga agcctcactg cctcctgagg ggaatccgca gatgtcactt cagagcccca     1680

catctatagc cagctacagc cagggcacag gatctgtgga tggtggagca gtggcagcag     1740

gggcttcagg ccgagaaagt gctgagggtc cccctcccct ctataacacc aaccatgact     1800

ttaaattctc ctactcagag atcaactttc aggatctaag ctggtccttc cgcaacctct     1860

ataagtccat gctggagaag tcctcttcct cctctcagca cggcttttct tctctcctgg     1920

gggacatccc accctcgaac aactactaca tgtatcagca gcagcagcca ccgccacctc     1980

aacagcagca gcagcagcag cagccgccac agccacctcc ccagcagtcc cagccacagc     2040

agcagcaggc acctgcccag ggcccctcag ctgtaggggg tgctcctcca ctgcacaccc     2100

caagcacaga tggttgtacc ccaccagggg gaaagcaagc tggggcggaa ggctatgggc     2160

ctccccctgt aatggccatg catccacccc cgctgcagca tggaggctac caccctcatc     2220

agcaccatcc ccactcccac cctgcccagc agccaccacc tccacagcca caggcacaag     2280

gccaggctcc catcaacaac actggctttg cctttccttc tgactggtgc tctaatattg     2340

actctttaaa ggaaagcttc aagatggtga atcggctcaa ttggtccagc attgagcagt     2400

cacaattctc agaactgatg gagagtctac gacaggcaga gcagaagaac tggaccctcg     2460

accagcatca cattgccaat ctgtgtgact ccctcaacca cttccttact cagactggtc     2520

acgtgccccc tcaagggggt acccaccgcc caccagcccc tgcccgtatt gctgactcct     2580

gtgccctcac cagtggcaaa caggagtcag ccatgagcca agtgaactct tatgggcacc     2640

cacaagctcc ccacctctac cctggcccat caccaatgta cccaatcccc acccaggact     2700

cagcaggata caatcgccca gcacaccata tggtccctcg gccatcagtg ccacctcctg     2760

gtgccaatga ggagatccct gatgacttcg actgggactt gatcacttag tgcatcacag     2820

agtgtggaca tcagcccagg gccgcgtggt gaaatctggc agtggggaaa gagcaacccc     2880

agcccgtccc ttccccccgt ctgtatatag acatatatcc tctttttgtt ctttctctgt     2940

cagagaagcc actgcaagat gctgccgaag ataaccctct ctttcctgcc tcattcttct     3000

ctcttccttc ctgttttttc ctagttcttt tattattatt cttatattat tattattatt     3060

attggttata tactgtccat agtctcctgt ccctacatca tggatcatgt ccaccttttg     3120

ctaatttaaa atcatcaggc tggaagatga agccatgata gctacagaga aaggttttag     3180

actccagttt acctttctct tggagaaact caatgctaat cccacctttt ggccctaaat     3240

tgttttttgt tcccatcagt ttcaggccag gactggagag gccacattac caagtagaaa     3300

gggtctgaaa cattacttgg cagccaagaa tttggaggtt ttaaaatggt gctaattctg     3360

tcctctgagg tcttccttgt ccctttatac cttcaatcct tacttctgcc agtctgtatt     3420

tcctatcaag ggtgaaagtg atgatggtgg tgcaggaggg tgacaataaa atcctagtgg     3480

aattggagac cattggaagg gatggaatat aagtcagtgt gaaactgagt atacactgcc     3540

atgttacatc agtgtccatt ggcttgtttt gagcctgttc tctaagaaga taggattggt     3600

tttagcccaa actctgcttc tatggtaggg catgaggaca actattcagc atggttttag     3660

cttcttggag atgattccaa cttaactatt ttggcttttt aaacataatt ttctctgaaa     3720

attaattgtg gctcttattt gcatttacga atgatcttcc catccctttt tcccattcag     3780

caaatattag tttgtcctcc tttaattgtt tgcccaaatc ttccacccat cttttttctt     3840

ccctcatttt ctgggattct caagaaagaa aaagtaaccc attatcactc tgagtttcgt     3900

cgtgccctga gacatgatgg gaatctcatt cccacctctc atagcagagc caaaccttta     3960

gtgttggtgg taggaggatg gggagaggaa aaaagagctg gcaaagaaat ggatagggaa     4020

tattttagtt ctttaaatat ataggcagat gcttctcttg gaatccagat catctggctg     4080

aagcttttgc aagtaggctt tgaggggtga aggagattgg tggaggagag taaataatct     4140

agaggcaaga gttcagtgag ggccaagggg gacccccaga aaaaggtatg gagctaactc     4200

atctctttta caaggggtgg ccatgactta ctgttgcaaa gtactcagtg tatatttaat     4260

gttgattgtt gaattttagt tacgagaggg aagaacaatt ttacttctgt ccttatttca     4320

cttgctgaaa agctgtggga caaaatgtat ggaatagaca aggccacttt ctttgtgatt     4380

tctgcttttc atgcatatta ttttatttac ccataatttc caagaggttt ggcgttccgc     4440

tctcctgctt ttttctttca tccacccctt tccttttttt ggaagggggt tatatatgag     4500

agttcattga agaagtccag tgaggctgaa gtaaaggggc aagatagggc agttaactaa     4560

agagcacttt atttctttga agcctttcta agaaagaaat gggggtgcga gtggcttgaa     4620

tctcccatga tgttggaggg cacttagtgg ggttgaagta tgacataata tttcccattg     4680

gggaaaggag aatttctctt agagggtggc aaaatgcctt tgcccagtgt ccctatttta     4740

ggcatctttt ccttccttat tccttccagt cagggtgtgt cctatacaaa acttcccatc     4800

agttctcctc aatattcccc atttgtaaat gatcacttct cttttctaaa cccttttcct     4860

gttcagatcc atacaggatt tgcaagggta ggatcataca tgcaaatgcc ccttgttcat     4920

ctgtgtcttc tgcaaactag tctcatgaag aattctggcg tgcagccagg gtagctgaag     4980

tttgggtctg ggactggaga ttggccatta ggcctcctga gattccagct cccttccacc     5040

aagcccagtc ttgctacgtg gcacagggca aacctgactc cctttgggcc tcagtttccc     5100

ctccccttca tgaaatgaaa agaatactac tttttcttgt tggtctagca ttgctggaca     5160

caaagtgtag tcattattgt tgtattgggt gatgtgtgca aaactgcaga agctcactgc     5220

ctataagagg aaataagaga gaaagtggag gagagggaca aaaggagtaa ttatttggta     5280

tagatccacc catcccaacc tttctctcct cagtccctgc tcctcatgtt tctggtttgg     5340

tgagtccttt gtgccaccac ccataatgct ttgcattgct gcatcctggg aagggggtat     5400

atggtctcac aagttgttgt cattgttttt ttgcatgctt tcttaataaa aaaaaaaaaa     5460

gaatgtttac agttttatct taaaaaaaaa aaaaaaaaa                            5499


<210>  2401
<211>  5246
<212>  DNA
<213>  homo sapiens

<400>  2401
agttccgggt gcgcggcccc ggatgttggc tgctcttgct gccgccgccg ctctcggggc       60

tgctcggggc ctcgaccgct cgcagtaggc accgttggga cctttcccgg gggggcggag      120

acgcacggag cggccggggg ctcggccggg ccgtcccggc ctgcgcagcc tgagattctc      180

tttgtggcca gatgggtttg tatggacagg cttgtccatc tgtaacttca ttaaggatga      240

catctgaact ggagagcagc ctaacgtcta tggactggtt accacagctc accatgagag      300

cagccatcca aaaatctgat gctacacaaa atgcacatgg aacaggaatt tctaagaaga      360

atgcactcct tgacccaaat acaactctgg accaggaaga agtccaacag cacaaagatg      420

ggaaacctcc atacagttat gccagcctca ttacatttgc aattaatagc tcacccaaaa      480

agaaaatgac tttaagtgaa atttatcagt ggatttgtga taacttccca tattatagag      540

aggctggcag tggttggaag aattccatac gacataatct gtcattgaac aaatgtttcc      600

ttaaagtgcc tcgatctaag gatgaccctg gaaaggggtc ctactgggca atagacacca      660

atccgaagga agatgtgctg cctactcggc caaagaagag ggcacgatct gtagaacggg      720

cctcaactcc atatagcata gattcagatt ctttgggaat ggagtgtatt atttcgggaa      780

gtgcctctcc aactctggca atcaacactg tgactaacaa agtaacattg tataacactg      840

atcaggatgg tagtgatagc ccacgcagta gccttaacaa cagtctctca gaccagagtt      900

tggcatctgt taatttgaac agtgttggaa gtgtgcatag ttatacaccg gtgacaagcc      960

atccagaatc agtctctcaa tcattaactc ctcagcagca accacagtac aaccttccag     1020

aaagagacaa gcaactactt ttctcagaat ataattttga agatcttagt gcctcatttc     1080

ggagccttta taagtcagtt tttgagcagt cacttagtca acaaggtttg atgaacatcc     1140

cttctgaatc ttcccagcag tcccacactt catgtaccta tcagcactct cccagcagta     1200

cagtgagcac tcacccacac agcaaccaaa gcagcctgtc caacagtcat ggcagtggcc     1260

tcaacaccac aggcagtaat tcggttgcac aggtctcact gtctcacccc cagatgcaca     1320

cacagccatc tccacatcct ccccatcgac cgcatggttt accgcagcat ccgcagcgtt     1380

ccccacaccc agcaccacac ccacagcaac acagccagct ccagtcccct cacccccagc     1440

atccctctcc acatcaacac atacagcacc atccgaacca tcagcatcag acgttaacac     1500

atcaggcacc cccaccccca caacaggtat cctgtaattc tggtgtttca aatgattggt     1560

atgcgacact tgatatgcta aaagaaagct gtcgaattgc cagcagtgtt aattggtcag     1620

atgtagacct ttcacagttt caaggtctga tggagagtat gagacaggca gatctcaaga     1680

actggtcttt agaccaggtt cagtttgccg atctttgttc ttctcttaat cagttcttta     1740

cacaaactgg ccttatacat tcacagagta atgttcaaca aaatgtttgt catggtgcca     1800

tgcatccaac aaaaccttcc caacacattg gaacaggaaa tttgtacata gattctaggc     1860

aaaatctccc tccttcagtg atgccacccc ctggttatcc tcatatccca caggcactca     1920

gcactccagg aacaacgatg gcaggccatc acagagccat gaaccagcag cacatgatgc     1980

cttcccaagc cttccagatg cggcgttccc tgcctccaga tgacatccag gatgactttg     2040

attgggattc aattgtgtag ggcttgtttc tgcaagacac cagaccctaa cgttaccttt     2100

ctgtgcagtg aagggaaagg tttaagagaa tccagttgag aaaacaaact tgctaatcac     2160

tttaccaatg ttatcaaaat tacttttgaa gacaatcaga aggattttag ctggataact     2220

tactgctttt atctgaccca agcaagtact acatgtttgt ctccctgcca gctgccctat     2280

gtagctccta actgttgtgt gatttggacg gctttttgca tatttgtgtc agtttgatgt     2340

taaccacaag tgccagactg atttttcaga cggagcctat tttgctgcaa gcagtttata     2400

taaagataca tatgtgtaaa tatatgtaca aaaattactg aaaggcttca gttttttcta     2460

attggattat tatgtcttga aagttattgt cagtttttat tccttgttag gctattttct     2520

gcaggatgct tttaactgat gtaggaaact gaaaggaaat agattttttc caaaacccag     2580

ttccccttat ttaatctttt ttagaaatgt gggtaatgaa ttctatctaa taagtcaagg     2640

aaaccagaat ttgacacact ccaacaatcc gaaggggcat gttgctcctg agcagcatga     2700

agaactgacc aaattggttt tgatgcttgg gggatcatag agtatttatg tctgcttttc     2760

taaatctgca ttataatagc tctaaaattt gttgattggt aagaaattgg gcattgcttg     2820

gctctttaaa cacatcagtg cttccacatt cacctatgta tttattattc aaaagtgtca     2880

ttttaatatt tattgctacc ttctgtgaat gcttagctcc tgtcgggttc attaaggaga     2940

aatgtgtctg aaagcacaga actattatta tttttttctt tttttgagat ggagtcttgc     3000

cctgttgccc aggctggagt gcagtggcac gatctcggct cactgcaacc tccgcctccc     3060

gggttcaagc aattctcctg cctcagcctc ccgagtagct gggagtgcag gtgcacaccg     3120

ccatgcctgg ctgatttttt gtattttagt agagatgggg tttcaccatg ttgcctgggc     3180

tggttgcaaa ctcttgagct caggcagtct gcctgcctca gcctcctaga gtgctgggat     3240

tacagacatg agccactgcg cctggcccag cgttactttt cttgataaga atttacagat     3300

aagacactca gagagacatt gtgtcattct ctatcatcac tccttttacc atgtgaatag     3360

atttctctgt cttggcattc ttgctgattc agacttatta gttaaatcgg atttttctgg     3420

aatttgaatc agatttcatt tgggcaacaa cagcagggca gggtttctaa agcaggtttc     3480

cccactcatc taggttgtct tgaaaggagg atagagccac ttacagtttt atttgcttca     3540

gtgtttaatg tagatattat gtggcctgct gtttctgttg tcttgtatgt ctgtgtatgc     3600

atgacatttg gtccctttct ttgaaatgca gcccctctta cgggtttttt agtggtggtg     3660

gtttgttttg tttcatatca tatcacagtt tgcatggact gattatctta gttttatgat     3720

aaaactagaa gaaatgaggg ttttttttta atgaatagat tttgaattga ttctttagac     3780

cccccaaaaa gtgtcagttc taatggggaa atatattcca tcaagtcaaa gagtaataac     3840

tgctcactag ttgcttttta gcatctctgg tcttatcagc catgctaaat cactttaatt     3900

agccttagtg attctatggt tgagtaatct ctacttgaac taaacaaaca tcttttgttt     3960

ctgtgtgtgt gtgctgtgtg tgagagtgtg cgcgcgcgtg tgtgtgtgtg tgttttaatg     4020

gagtgttgcc ttgaatgaat cactgggaag ccagccatgg taagggctgg tgaggttggg     4080

gagaaaggaa gagctttatg tttctctgtt gtttggaccc tacttggcat gaaaaaggaa     4140

gctcagttcc agccccttgg atcaacgaaa atcagaggat tctggaaagg cagccaactt     4200

gcgcctctta gaaggatcag aggcaagatg agatggcagc ctgcagagta aatgcttgaa     4260

aaaagagggg tgattttcaa tggtttgctt aagtcactgt tttctagaca ccaaaatagc     4320

tgttttgaaa ctgttttaat tgcttgggta gcaatgtgca ctttaaacaa tttggatatt     4380

ggaatgcagt ctcatactga gtgatttgag tagaaccact gatgatgatt ttataaattg     4440

tgtgaagcga atttcccatt tggcaatcat ttactgattt gcagtgatga atatttttat     4500

gagaatttaa acttagcaag aatggccatg gaggcaaagc cttcacccag acccatccca     4560

ctctcctgtg atccaggtgg tccaggagcc caggacaggc cttttctgtg ggccctggcc     4620

agacagggtt acctggtgag gtgcagagag tccctctagt ggccattttg tatggtagtt     4680

gctaatgcag aacaagttct gtcttgggct taaattgact gaagacttta gggggaaaga     4740

atagtaaatg catgtaaaca aatggggaca ctctgttcag gagaataatc cgactggcat     4800

ttgtggcagt ttttgaaatg taaatgtatt catgtgtgtt cttgtaaata cgtgtcgctc     4860

agatgtcctt tgaagtggga gggaatcaat ccggggataa tttcaaatgg aatagagtat     4920

tttgatattg ttcattcaga gggtgatgtg tacatatcta tattgtatat atgtgatgaa     4980

aatgcattgg ctttttgtgc agatacaacc tgctctctgt actgctgttg gacagtcagt     5040

gttttaatgt ttctacagtt ttgctattgc acgatttcat attttgcctc tatgatgaac     5100

ggcaaccatt atttgtaact gtttagtgct gtaaagaaat attccaagtg tcattaggat     5160

tgttgctgcc agaactgata tgcatgaatg gcacttaaaa taaatatatt atgttaactc     5220

tatttacaac aaaaaaaaaa aaaaaa                                          5246


<210>  2402
<211>  7226
<212>  DNA
<213>  homo sapiens

<400>  2402
agcagttcag agccccagtt gcagacgact tgtcctgcca ccaccatgag ttctgaatgt       60

gatggtggtt ccaaagctgt gatgaatggc ttggcacctg gcagcaatgg gcaagacaaa      120

gcaactgccg accctttacg cgcacgctct atttctgctg ttaaaatcat tcctgtgaag      180

acagtgaaaa acgcctcagg cctagttctc cctacagaca tggatcctac aaaaatctgc      240

actgggaagg gagcggtgac tctccgggcc tcgtcttcct acagggaaac cccaagcagt      300

agccctgcga gccctcagga aacccggcaa cacgaaagca aaccaggtct ggagccagag      360

ccttcttcag cagatgagtg gaggctttct tccagtgctg atgccaatgg aaatgcccag      420

ccctcttcac tcgctgccaa gggctacaga agtgtgcatc ccaaccttcc ttctgacaag      480

tcccaggatg ccacttcctc cagtgcagcc cagccggagg taatagttgt ccctctctac      540

ctggttaata ctgacagagg gcaagaaggc actgccagac ctccaacacc tctggggcct      600

cttggctgcg tccccacaat cccagcgact gcctctgccg cctcacctct gaccttcccg      660

actctagatg atttcattcc ccctcatctg cagaggtggc cccaccacag ccagccagcc      720

cgcgcctctg gctcctttgc ccccattagc cagacgccac catccttctc accaccacct      780

ccgctggtcc ctcctgcccc ggaggacctc cgcagagtct cggagcctga cctcacggga      840

gctgtttcga gtaccgattc cagtcctcta ctaaatgaag tttcttcttc ccttattgga      900

actgattccc aagcctttcc atcagttagc aagccttcat ccgcctatcc ctccacaacg      960

attgtcaatc ctactattgt gctcttgcaa cacaatcgag aacagcaaaa acgactcagt     1020

agcctttcag atcctgtctc agaaagaaga gtgggagagc aggactcagc accaacccag     1080

gaaaaaccca cctcacctgg caaggctatt gaaaaaagag caaaggatga cagtaggcgg     1140

gtggtgaaga gcactcagga cttaagcgat gtttccatgg atgaagtggg catcccactc     1200

cggaacactg agagatcaaa agactggtac aagactatgt ttaaacagat ccacaaactg     1260

aacagagaca ctcctgaaga aaacccttat ttccctacgt acaaattccc tgaacttcct     1320

gaaatccagc aaacttccga agaggacaat ccttacactc ccacctacca gtttcctgca     1380

tctactccta gtcctaaatc tgaagatgat gattcagatc tgtactctcc cagatactca     1440

ttttctgaag acacaaaatc tcccctttct gtgcctcgct caaaaagtga gatgagctac     1500

attgatggtg agaaggtagt caagaggtcg gccacactac ccctcccagc ccgctcttcc     1560

tcactgaagt caagctcaga aagaaatgac tgggaacccc cagataagaa agtagacaca     1620

agaaaatatc gtgcagagcc caagagcatt tacgaatatc agcctggcaa gtcttccgtt     1680

ctgaccaacg aaaagatgag tcgggatata agcccagaag agatagattt aaagaatgaa     1740

ccttggtata aattcttttc ggaattggag tttgggaaac cgcctcccaa aaagatatgg     1800

gattatactc ctggagactg ctctatcctt cctagagagg atagaaagac taatctagac     1860

aaagatctca gcctctgcca gacagagtta gaggcagatt tagaaaaaat ggagacgctt     1920

aataaagcac ccagtgcaaa cgtgccacag agctcagcca tcagccctac tccggaaatt     1980

tcttcagaga ctcctggata tatatattct tccaacttcc atgcagtgaa gagggaatca     2040

gacggggctc ctggggatct cactagcttg gagaatgaga gacaaattta taaaagtgtc     2100

ttggaaggtg gtgacatccc tcttcagggc ctgagtgggc tcaagcgacc atccagctct     2160

gcttccacta aagattcaga atcgccaaga cattttatac cagctgatta cttggaatcc     2220

acggaagaat ttattcgaag acgtcatgat gataaagaga aacttttagc ggaccagaga     2280

cgacttaaac gcgagcaaga agaggctgat attgcagctc gacgccacac aggcgtcatt     2340

ccgacgcacc atcagtttat cactaatgag cgctttgggg acctcctcaa tatagacgat     2400

actgcaaaaa ggaaatctgg gtcagagatg agacctgcca gagccaaatt tgactttaaa     2460

gctcagacac taaaggagct tcctctgcag aagggagata ttgtttacat ttataagcaa     2520

attgatcaga actggtatga aggagaacac cacggccggg tgggaatctt cccacgcacc     2580

tacatcgagc ttcttcctcc tgctgagaag gcacagccca aaaagttgac accagtgcag     2640

gttttggaat atggagaagc tattgctaag tttaacttta atggtgatac acaagtagaa     2700

atgtccttca gaaagggtga gaggatcaca ctgctccggc aggtagatga gaactggtac     2760

gaagggagga tcccggggac atcccgacaa ggcatcttcc ccatcaccta cgtggatgtg     2820

atcaagcgac cactggtgaa aaaccctgtg gattacatgg acctgccttt ctcctcctcc     2880

ccaagtcgca gtgccactgc aagcccacag ttttccagtc acagcaagct catcacgcca     2940

gccccctcat ctctgcccca ctcccgccga gccctgtccc ccgagatgca cgctgtcacc     3000

tctgagtgga tctcactgac tgtgggggtc ccaggcaggc gttctctggc cctgacccca     3060

cccttgcctc ctctgccaga ggcttctatc tataacactg accacctcgc cttgtcacca     3120

agggccagtc cctccctgtc tctcagcctc ccccatttga gttggtcaga tcgtcccacc     3180

ccacgatcag tagcttctcc actggcccta ccttccccac acaaaaccta ctccctagca     3240

cctacttccc aggcctccct tcacatgaat ggagacggtg gtgtccacac gccatcttca     3300

ggcatccacc aagatagctt cttgcagctg ccgctgggga gctctgatag tgtcatctcc     3360

cagcttagtg atgcctttag cagccagagc aagaggcagc catggcgcga agagagtgga     3420

caatatgaga ggaaagcaga gaggggggca ggcgaaagag gccctggtgg acccaagatc     3480

tctaagaaga gctgcttgaa gccttcagac gtggtcaggt gcctgagtac tgaacagaga     3540

ctctcagatc tcaacacccc tgaggagagc cggcccggca agcccctggg tagcgctttt     3600

ccaggaagtg aggctgagca gacagagcgg catagaggtg gcgagcaggc ggggaggaaa     3660

gctgctcgga gaggtgggag ccagcaacct caagcccagc agcgaagagt cacccccgac     3720

aggagtcaaa cctcacaaga tttatttagc tatcaagcat tatatagcta tataccacag     3780

aatgatgatg agttggaact ccgcgatgga gatatcgttg atgtcatgga aaaatgtgac     3840

gatggatggt ttgttggtac ttcaagaagg acaaagcagt ttggtacttt tccaggcaac     3900

tatgtaaaac ctttgtatct ataagaagac tgaaaaccat ggagattatt tttattggag     3960

gaggaagcat cattcatgaa ccgatctttt tagttgagtc agtaggaaaa ttaatacagt     4020

ggataaagta agaagcaaaa gacagggaca gagaagtgtt gtgtttaaaa cccaagcctg     4080

tctaaggtta ctgtgtatta gacagggccg aactagtgtg ctgagcaaaa agaattgaag     4140

caaattgtat ttacttagcc gcttctggga gccacttcag cctttcccct cccctccact     4200

tcttgggtaa tctgacctga agcatagtcc aggagcagag ttagccagaa atgcctcctg     4260

ctgccccagc cttagagagc tcccatctca atcattgagc ctgaaggctt caagcccaag     4320

aatgcaacaa gacccccagc ctacatttct cagctcccct ggagccagct gatcctgtaa     4380

cgctgctgga ggtcagtctg agctaccaag actgtcccta gacaaaggtg gagtccccca     4440

cactgcccaa gaccaaatcc ctcactcaac ctgctgaggt gtggatgggg aaacagaggc     4500

aaaactgagg cacctgatgc attcagcctg ctgtgcagca gtgccattga ctgccctgat     4560

gttcagagag aaacgcacac aaggtttgcc catgagaatt ggggagcaga tggccaagca     4620

gataggttat gtctgttttc tgagtgatga agtcaggaag ccctgtggct ctggaggcca     4680

cttgtggttc attcttttcc catatccttg gcttttagaa atggttacct tcaggacagt     4740

gcagctgcat ttatcagagc actattgcta agttttcttt tctggcttgt gtttttctgg     4800

gacagtttag aattgggagg cctattctca tagaacacca aaaatgatgt tcagtgattc     4860

atttaacata caccaatgta ctctggctgc tggggggaca accataagca agacatgccc     4920

agggtttgcc gtggctccag atctactccc tgtaggagtt caaggatcac acaaacggta     4980

gtaaccaggg ttgtgaatct gagtacaccc tggcaaggct tctcttcaga ctgaagcagc     5040

aattctgcca ctaccagcag caaccaggac gtctgttctt tgtgggggcc agatcagaag     5100

agagaggccc ctgtgacgcc cgggctgctt ggtcacaact ctgtccaatt caaggatgtt     5160

tatcggcctc tcttagatcc tgagtgagac aaatacagaa atgacccatt ccctgcccac     5220

cagaaactca gaggtgattg gggagactga cacaggaaaa tgaacttaat caagagagac     5280

tgtgatatgt gctaagaagg gtgtgaggga gggagagatg aattttccct ggagggatcc     5340

tagaaagcat tgtcatattg ccatctccat tagctcactt ttaaacaact agggtgctgg     5400

aagaaccttt gtctgagggt agttcatagc tggaaatact tggaatattt tccagagtct     5460

ctaaactctc atcttccccc acagatacac atccaagctc acaaatagga gtagcaattc     5520

taggtggtag ggttgtgtac ggaacccctg gctgtctgca tatatctcag aattacccca     5580

ggaccattgt cccaaagtct agagtcttta caggtaggca aaatttgttt tcaatgcctg     5640

tgcctcagct gctgtcacaa atacccatct taggatccca tcagcttccc atcccccacc     5700

agacagccac agtaccctca ctttctccct attgttcttt caaatcctgt tctcaggaaa     5760

gaaactgcca ctaattcatt cacactaagg tgtaaatgat tgataatagg aatgagttac     5820

ctcttcccac agacatttgt ttttaagtat gacagagcag ggccttaatc ccaagggaaa     5880

aggttatgga actggagggg gtgagctttc tgggtagaag gagacttcct gaatttcctt     5940

aaaacccagt aagagtaaga cctgttgttt tggaaggtct gctccaccat ctaagagcac     6000

tgtttttttt tttttgttgt tgttgttgtt ttacggtctc tgagggaata tagtaaaaat     6060

gcatatgcac gtgcaatttg cacggcagca tttcaccgat tgtggactgt attggctaat     6120

gtgtttcctg gtctttagat gcaaaccatt aataacacta tcttatctca tagttttttc     6180

aggggtgctt cttgattagt agggaatttt gaacacctct ttaaatacag ctagaaaata     6240

aaaccaattt gtaaagccac atttgcatat gatgccagcc tcacgcattt gtatatctcc     6300

agaaattcag gtatgcctca ccaatttgcc cgtctttaat aaaatcttgt gttaaaattt     6360

gcatcacgtc gccttcctat gtatgacgaa acaagaaaca gagatttcca attgctcttt     6420

tgtcttcaga catttagtaa tataaagtac ctatttttat gctgaaatgt ttatacaggt     6480

ttattaatag caagtgcaac taactggcgg catgccttgc aacacatttt gatatattag     6540

ccatgcttcc gggtaaaggc aagccccaaa ctccttatct tttgcagtct ctctgggatc     6600

agtaaaagaa aaaaaaaata atgtgcttaa gaagtgggac tgtaaatatg tatatttaac     6660

tttgtatagc ccatgtacct accttgtata gaaaaataat tttaaaaatt tgaatggaag     6720

ggggtaaagg aagtcatgaa gtttttttgc atttttattt aaatgaagga attccaaata     6780

actcacctac agatttttag cacaaaaata gccattgtaa agtgttaaaa tttacgataa     6840

gtattctatt ggggaggaaa ggtaactctg atctcagtta cagttttttt ttccttttta     6900

atttcattat tttgggtttt tggtttttgc agtcctattt atctgcagtc gtattaagtc     6960

ctattgctag aataggttac tacaaaaaag gttatattct gaaagaaaaa taactgacat     7020

tatatataac caattaattt aaagtattgc catttaaatt acacactgag agcatgtcct     7080

atgcagacat agatttttct gttcatttat ttttcttcat tgcagtggat tgatttgata     7140

aatagatgtg ttgaattact acatttgctg tacatattat ttaataaact ttattcagaa     7200

ttgcgtggca aaaaaaaaaa aaaaaa                                          7226


<210>  2403
<211>  9050
<212>  DNA
<213>  homo sapiens

<400>  2403
ccctggaggg agagagagcc agagagcggc cgagcgccta ggaggcccgc cgagcctcgc       60

cgagccccgc cagccccggc gcgagagaag ttggagagga gagcagcgca gcgcagcgag      120

tcccgtggtc gcgccccaac agcgcccgac agcccccgat agcccaaacc gcggccctag      180

ccccggccgc acccccagcc cgcgccagca tgatgaacaa cagcggctac tcagacgccg      240

gcctcggcct gggcgatgag acagacgaga tgccgtccac ggagaaggac ctggcggagg      300

acgcgccgtg gaagaagatc cagcagaaca cattcacgcg ctggtgcaat gagcacctca      360

agtgcgtggg caagcgcctg accgacctgc agcgcgacct cagcgacggg ctccggctca      420

tcgcgctgct cgaggtgctc agccagaagc gcatgtaccg caagttccat ccgcgcccca      480

acttccgcca aatgaagctg gagaacgtgt ccgtggccct cgagttcctc gagcgcgagc      540

acatcaagct cgtgtccata gacagcaagg ccatcgtgga tgggaacctg aagctgatcc      600

tgggcctgat ctggacgctg atcctgcact actccatctc catgcccatg tgggaggatg      660

aagatgatga ggatgcccgc aaacagacgc ccaagcagcg gctgcttggc tggatccaga      720

acaaggtgcc ccagctgccc atcaccaact tcaaccgtga ctggcaggac ggcaaagctc      780

tgggcgccct ggtggacaac tgcgcccccg gtctctgccc cgactgggag gcctgggacc      840

ccaaccagcc cgtggagaac gcccgggagg ccatgcagca ggccgacgac tggcttgggg      900

tgccccaggt cattgcccct gaggagattg tggaccccaa cgtggatgag cattctgtta      960

tgacctacct gtcccagttc cccaaggcca agctcaaacc tggtgcccct gttcgatcca     1020

agcagctgaa ccccaagaaa gccatcgcct atgggcctgg catcgagcca cagggcaaca     1080

ccgtgctgca gcctgcccac ttcaccgtgc agacggtgga cgcgggcgtg ggcgaggtgc     1140

tggtctacat cgaggaccct gaaggccaca ccgaggaggc taaggtggtt cccaacaatg     1200

acaaggatcg cacctatgct gtctcctatg tgcccaaggt cgctgggtta cacaaggtga     1260

ccgtgctctt tgctggccag aacattgaac gcagtccctt tgaggtgaac gtgggcatgg     1320

ccctgggaga tgccaacaag gtgtcagccc gtggccctgg cctggaacct gtgggcaatg     1380

tggccaacaa acccacctac tttgacatct acactgcggg ggccggcact ggcgatgttg     1440

ctgtggtgat cgtggaccca cagggccggc gggacacagt ggaggtggcc ctggaggaca     1500

agggtgacag cacgttccgc tgcacataca gacctgccat ggaggggcca cataccgtgc     1560

atgtggcctt tgcgggtgcc cccatcaccc gcagtccctt ccctgtccat gtgtcggaag     1620

cctgtaaccc caacgcctgc cgcgcctctg ggcgaggcct gcagcccaag ggtgttcgcg     1680

tgaaagaggt ggctgacttc aaggtgttta ccaagggtgc cggcagcggg gagctcaagg     1740

tcacggtcaa ggggccaaag ggcacagagg agccagtgaa ggtgcgggag gctggggatg     1800

gtgtgttcga gtgcgagtac tacccggtgg tgcctgggaa gtatgtggtg accatcacgt     1860

ggggcggcta cgccatccct cgcagcccct ttgaggtaca ggtgagccca gaggcaggag     1920

tgcaaaaggt ccgggcctgg ggtcctggtt tggagactgg ccaggtgggc aagtcagccg     1980

attttgtggt ggaagccatt ggcaccgagg tggggacact gggcttctcc atcgaggggc     2040

cctcacaagc caagatcgaa tgtgacgaca agggggatgg ctcctgcgat gtgcggtact     2100

ggcccacgga gcctggggag tacgctgtgc acgtcatctg tgacgatgag gacatccgag     2160

actcaccctt cattgcccac atcctgcccg ccccacctga ctgcttccca gataaggtga     2220

aggcctttgg gcctggcctg gagcctaccg gctgcatcgt ggacaagccc gctgagttca     2280

ccattgatgc tcgtgcagct ggcaagggag acctgaagct ctatgcccag gacgccgacg     2340

gctgtcccat cgacatcaag gtgatcccca acggcgacgg caccttccgc tgctcctacg     2400

tgcccaccaa gcccattaag cacaccatca tcatctcctg gggaggcgta aacgtgccca     2460

agagcccctt ccgggtgaac gtgggcgagg gcagccaccc cgagcgggta aaggtgtacg     2520

gccccggagt ggagaagaca ggcctcaagg ccaatgagcc cacctacttc acggtggact     2580

gcagcgaggc ggggcaaggc gacgtgagca tcggcatcaa gtgcgcccca ggcgtggtgg     2640

gccctgcaga ggctgacatt gacttcgaca tcatcaagaa tgacaacgac accttcaccg     2700

tcaagtacac gccaccaggg gcgggccgct acaccatcat ggtgctgttt gccaaccagg     2760

agatccccgc cagccccttc cacatcaagg tggacccatc ccacgatgcc agcaaagtca     2820

aggccgaggg ccctgggctg aatcgcacag gtgtggaagt cgggaagccc acccacttca     2880

cggtgctgac caagggagcc ggcaaggcca agctggatgt gcagtttgca gggacagcca     2940

agggcgaggt tgtgcgggac tttgagatca tagacaacca tgactactcc tacactgtca     3000

agtacaccgc tgtccagcag ggcaacatgg cagtgacagt gacttatggc ggggaccctg     3060

tccccaagag cccctttgtg gtgaatgtgg cacccccgct ggacctcagc aaaatcaaag     3120

ttcagggcct taatagcaag gtggctgtgg gacaggaaca agcattctct gtgaacacac     3180

gaggggctgg cggtcagggc caactggatg tgcggatgac ttcgccctct cgccggccca     3240

tcccctgcaa gctggagcca ggcggtggag cggaagccca ggctgtgcgc tacatgcccc     3300

cggaggaggg gccctacaag gtggatatca cctacgatgg tcacccggtg cctggcagcc     3360

cgtttgctgt ggagggtgtc ctgccccctg atccctccaa ggtctgtgct tatggcccgg     3420

gtctcaaggg tggactggta ggcacccccg cgccattctc catcgacacc aagggggctg     3480

gcacaggtgg cctggggctg accgtagagg gcccctgcga ggccaagatc gagtgccagg     3540

acaatggtga tggctcatgt gctgtcagct acctgcccac ggagcctggc gagtacacca     3600

tcaacatcct gtttgctgag gcccacatcc ctggctcgcc cttcaaagcc accattcggc     3660

ctgtgtttga cccgagcaag gtgcgggcca gtggaccggg cctggagcgc ggcaaggtcg     3720

gtgaggcagc caccttcact gtggactgct cagaggcagg cgaggcggag ctgaccattg     3780

agatcctgtc ggatgccggg gtcaaggccg aggtgctgat ccacaacaac gcggatggca     3840

cctaccacat cacctacagc cctgccttcc ctggcaccta caccattacc atcaagtatg     3900

gcgggcatcc cgtgcccaaa ttccccaccc gtgtccatgt gcagcctgcg gtcgatacca     3960

gtggcgtcaa ggtctcaggg cctggtgttg agccacacgg tgtcctgcgg gaggtgacca     4020

ctgagttcac tgtggatgca agatccctaa cagccacagg cggcaaccac gtgacggctc     4080

gtgtgctcaa cccctcgggg gccaagacag acacctatgt gacagacaat ggggacggca     4140

cctaccgagt gcagtacacc gcctacgagg agggcgtgca tctggtggag gtcctgtatg     4200

atgaggtcgc tgtgcccaag agccccttcc gagtgggcgt gaccgagggc tgtgatccca     4260

cccgcgtccg agccttcggg ccaggcctgg agggtggctt ggtcaacaag gccaaccgat     4320

tcactgtgga gaccagggga gcgggcaccg ggggccttgg cctagccatc gagggtccct     4380

cggaagccaa gatgtcctgc aaggacaaca aggatggtag ctgcaccgtg gagtacatcc     4440

ccttcactcc tggagactat gacgtcaaca tcaccttcgg ggggcggccc atcccaggga     4500

gcccgttccg cgtgccagtg aaggatgtgg tggaccctgg gaaggtgaag tgctcagggc     4560

cagggctggg ggctggtgtc agggcccggg ttcctcagac cttcacagtg gactgcagtc     4620

aagctggccg ggcgcccctg caggtggctg tgctgggccc cacaggtgtg gccgagcctg     4680

tggaggtgcg ggacaatgga gatggcaccc acactgtcca ctacacccca gccactgacg     4740

ggccctacac ggtagccgtc aagtatgctg accaggaggt gccacgcagc cccttcaaga     4800

tcaaggtcct cccagctcat gatgccagca aggtgcgggc cagcggccca ggcctcaacg     4860

cctctggcat ccctgccagc ctgcctgtgg agttcaccat cgacgcacgg gacgcgggcg     4920

aggggttgct cactgtccag atcttggacc ccgagggtaa gcccaagaag gccaacatcc     4980

gggacaatgg ggatggcacg tacactgtgt cctacctgcc ggacatgagt ggccggtaca     5040

ccatcaccat caagtatggc ggtgatgaga tcccctactc gcccttccgc atccatgctc     5100

tgcccactgg ggatgccagc aagtgcctcg tcacagtgtc cattggaggc catggcctgg     5160

gtgcctgcct gggccctcga atccagattg ggcaggagac ggtgatcacg gtggatgcca     5220

aggcagccgg tgaggggaag gtgacatgca cggtgtccac gccggatggg gcagagctcg     5280

atgtggatgt ggttgagaac catgacggta cctttgacat ctactacaca gcgcccgagc     5340

cgggcaagta cgtcatcacc atccgcttcg ggggtgagca catccccaac agccccttcc     5400

acgtgctggc cacagaggag ccagtggtgc ctgtggagcc aatggagtcc atgctgaggc     5460

ccttcaacct ggtcatcccc ttcgcggtgc agaaagggga gctcacagga gaggtgcgga     5520

tgccctcggg gaagacggca cggcccaaca tcaccgacaa caaggacggc accatcacgg     5580

tgaggtatgc acccactgag aaaggcctgc accagatggg gatcaagtat gacggcaacc     5640

acatccctgg gagcccctta cagttctatg tggatgccat caacagccgc catgtcagtg     5700

cctatgggcc aggcctgagc catggcatgg tcaacaagcc agccaccttc actattgtca     5760

ccaaagatgc tggagaaggg ggtctgtcac tggccgtgga gggcccatcc aaggcagaga     5820

tcacctgtaa ggacaacaag gatggcacct gcaccgtgtc ctatctgccg actgcgcctg     5880

gagactacag catcatcgtg cgcttcgatg acaagcacat cccggggagc cccttcacag     5940

ccaagatcac aggtgatgac tccatgagga cctcacagct gaatgtgggc acctccacgg     6000

acgtgtcact gaagatcacc gagagtgatc tgagccagct gaccgccagc atccgtgccc     6060

cctcgggcaa cgaggagccc tgcctgctga agcgcctgcc caaccggcac attgggatct     6120

ccttcacccc caaggaggtc ggggagcacg tggtgagcgt gcgcaagagt ggcaagcatg     6180

tcaccaacag ccccttcaag atcctggtgg ggccatctga gatcggggac gccagcaagg     6240

tgcgggtctg gggcaagggg ctttccgagg gacacacatt ccaggtggca gagttcatcg     6300

tggacactcg caatgcaggt tatgggggct tggggctgag tattgaaggc ccaagcaagg     6360

tggacatcaa ctgtgaggac atggaggacg ggacatgcaa agtcacctac tgccccaccg     6420

agcccggcac ctacatcatc aacatcaagt ttgctgacaa gcacgtgcct ggaagcccct     6480

tcactgtgaa ggtgaccggc gagggccgca tgaaggagag catcacccgg cggagacagg     6540

caccttccat cgccaccatc ggcagcacct gtgacctcaa cctcaagatc ccaggaaact     6600

ggttccagat ggtgtctgcc caggagcgcc tgacacgcac cttcacacgc agcagccaca     6660

cctacacccg cacggagcgc acggagatca gcaagacgcg gggcggggag acaaagcgcg     6720

aggtgcgggt ggaggagtcc acccaggtcg gcggggaccc cttccctgct gtgtttgggg     6780

acttcctggg ccgggagcgc ctgggatcct tcggcagcat cacccggcag caggagggtg     6840

aggccagctc tcaggacatg actgcacagg tgaccagccc atcgggcaag gtggaagccg     6900

cagagatcgt cgagggcgag gacagcgcct acagcgtgcg ctttgtgccc caggaaatgg     6960

ggccccatac ggtcgctgtc aagtaccgtg gccagcacgt gcccggcagc ccctttcagt     7020

tcactgtggg gccgctgggt gaaggtggtg cccacaaggt gcgggccgga ggcacagggc     7080

tggagcgagg tgtggccggc gtgccagccg agttcagcat ctggacccgg gaggctggcg     7140

ctgggggcct gtccattgct gtggagggtc ctagcaaagc ggagattgca tttgaggatc     7200

gcaaagatgg ctcctgcggc gtctcctatg tcgtccagga accaggtgac tatgaggtct     7260

ccatcaagtt caatgatgag cacatcccag acagcccctt tgtggtgcct gtggcctccc     7320

tctcggatga cgctcgccgt ctcactgtca ccagcctcca ggagacgggg ctcaaggtga     7380

accagccagc gtcctttgcc gtgcagctga acggtgcccg gggcgtgatt gatgcccggg     7440

tgcacacacc ctcgggggct gtggaggagt gctacgtctc tgagctggac agtgacaagc     7500

acaccatccg cttcatcccc cacgagaatg gcgtccactc catcgatgtc aagttcaacg     7560

gtgcccacat ccctggaagt cccttcaaga tccgcgttgg ggagcagagc caggctgggg     7620

acccaggctt ggtgtcagcc tacggtcctg ggctcgaggg aggcactacc ggtgtgtcat     7680

cagagttcat cgtgaacacc ctgaatgccg gctcgggggc cttgtctgtc accattgatg     7740

gcccctccaa ggtgcagctg gactgtcggg agtgtcctga gggccatgtg gtcacttata     7800

ctcccatggc ccctggcaac tacctcattg ccatcaagta cggtggcccc cagcacatcg     7860

tgggcagccc cttcaaggcc aaggtcactg gtccgaggct gtccggaggc cacagccttc     7920

acgaaacatc cacggttctg gtggagactg tgaccaagtc ctcctcaagc cggggctcca     7980

gctacagctc catccccaag ttctcctcag atgccagcaa ggtggtgact cggggccctg     8040

ggctgtccca ggccttcgtg ggccagaaga actccttcac cgtggactgc agcaaagcag     8100

gcaccaacat gatgatggtg ggcgtgcacg gccccaagac cccctgtgag gaggtgtacg     8160

tgaagcacat ggggaaccgg gtgtacaatg tcacctacac tgtcaaggag aaaggggact     8220

acatcctcat tgtcaagtgg ggtgacgaaa gtgtccctgg aagccccttc aaagtcaagg     8280

tcccttgaat cccaaaagtg cctccccagc ctcagccccc acctccagcc acacacacat     8340

tacacacaca cacacacaca cacaaatgtg ccacacccag acacgcacag aatcagacac     8400

tacaaacacc tgccttgggg gtgaagtgaa ggcccagcct ccccacccca ccgcgcccca     8460

ggggttggag gaccttgtct gtgtcaggac agtgtccctc cctgggaatg tgacatgagg     8520

gccgactggg gccaggctca ggggcagagg ctgggacaca aggggctggc gagggctgcg     8580

aggccaggga agccctgagt ttctggcggg gctgagcagt gggggagcat tgtgttgtgg     8640

gtgtctgtgt gtgaggtcac cctcaaactg caccgccggc cagataccct cctgaccccg     8700

aggacttggt ctggtctctc tggtggctac aaccccagag ttttaaggac ttggaaagga     8760

aagcacaatc agagaagaaa acagcccccg aaccagcagg agtggcctgg cacatggacc     8820

ggcctgagcg atgtgcactc cacccaagcc aggctcccag ggggcctgat ttctctctca     8880

ctgtctcttt ttttaaaatg gttgcacggc tctgccccat ggggggcctt ttttacacac     8940

tgcgaggccc agctttctag gggacttttg cacatgtcat gcagctcagc tgggagctgc     9000

ttaggtggaa aactccaaat aaagtgcggc tgtcgcagaa aaaaaaaaaa                9050


<210>  2404
<211>  6900
<212>  DNA
<213>  homo sapiens

<400>  2404
agcgcaggtc ccgacagagg tcgccgggtg gtggcgtcag ctgcggcgcc ctccgcgtgg       60

aaattagccg gttgcccggg caaatcaggg aggaagggag ggagctgaac acggaagtgg      120

tggcggcgcc cagggaaccg gcggaggcga tgaccgtgac ggctgggttg ggaccggaac      180

gccgaagcgg ggttgggggt ggcagaaaag catctgcttt gtaagaccta cacgaggtgc      240

aggagtggtt gggcctcccc tctccactta agcaagcgcc cagactgatg gcgatggtga      300

tggcagcagt tactcgcaca accccagtta agctgcgctc cgggagatac atccagaaag      360

tgcccagaag aaacttcctg ctggaaaaaa tgaaaaagca gtatttataa cattagaatc      420

tggataattt gttaacatgg cagaaaataa tgaaaatatt agtaaaaatg tagatgtaag      480

gcccaaaact agtcggagca gaagtgccga cagaaaagac ggttatgtgt ggagtggaaa      540

gaagttatct tggtcaaaaa agagtgagag ttattcagat gctgagacag tgaatggtat      600

agagaaaacc gaagtgtctt taaggaacca agaaaggaag cacagctgtt catccattga      660

gttggactta gatcattcct gtgggcatcg atttttaggc cgatctctta aacagaaact      720

gcaagatgcc gtggggcagt gttttccaat aaagaattgt agtagtcggc actcttcagg      780

gcttccgtct aaaaggaaaa ttcatatcag tgaactcatg ttagataagt gtcctttccc      840

acctcgatca gatttagcct ttaggtggca ttttattaaa cgacacactg ctcctataaa      900

ttccaaatca gatgaatggg taagcacaga cttgtctcag actgaattga gggatggtca      960

gctaaaacga agaaatatgg aagaaaatat aaactgtttc tcacatacca atgttcagcc     1020

ctgtgtcata accaccgaca atgctttgtg tagagaaggt cctatgactg gctctgtgat     1080

gaacctggtt tcaaataaca gtatagaaga tagtgatatg gattccgatg atgaaattct     1140

aacactttgc acaagttcca gaaaaagaaa caaacccaaa tgggatttgg atgatgaaat     1200

cctgcagttg gaaacacctc ctaaatacca cacgcagatt gattatgtcc actgtcttgt     1260

accagacctc cttcagatca ataacaaccc atgttactgg ggagtgatgg ataaatacgc     1320

agccgaagca ctactggaag gaaaaccaga gggtaccttt ttacttcgag actcagcaca     1380

ggaagactat ttattctctg ttagttttag acgctatagt cgttctcttc atgctagaat     1440

tgaacagtgg aatcacaact ttagctttga tgcacatgac ccctgtgtct tccattctcc     1500

tgacattact gggctcctag aacattataa ggacccaagc gcctgtatgt tctttgaacc     1560

acttctatcc actcccttaa ttcggacttt ccctttttcc ctgcagcata tatgcagaac     1620

agttatttgt aactgtacaa cttatgatgg catcgatgcc cttccaattc cttcttctat     1680

gaaattatat ctgaaggaat atcattataa atcaaaagtt agagtactca ggattgatgc     1740

accagaacag caatgctagt aacaggatgg gaacatggga atgataatat atattttttc     1800

ttttaatatt ttatttttct ttttatgcca ctttggattt ttctacaaag gcagtggtgt     1860

ccaaaataaa atctctgccc taaattttac taataaatcc atttttctag tgatacacaa     1920

attgtttaag gttatacact cgagcttaaa tagatatttt taaccaggtg tttggttttt     1980

gtttttaccg tgtaggttgt atacttacat tttttctttc cttaatttat acatgatcct     2040

ttttccttaa tttatacatg atccaggcac atttgaaatt tggtaggcat tgcaaacaca     2100

tttgaatatt gtgtatttca tactattctt taaaagtaat cttatgtcct ttcctacatg     2160

taaaatattt tgttaatcta tgccattagt agtattatat ataaaatata gttccccgtc     2220

ccccttttca ttgagtttga tattcttcag taaagctgaa tgttgtaatt caccattcat     2280

actaatgtta ttgacttttg taacttacta atagggatgt taaaagtaac aaaaccaagt     2340

caaacttggt gtatttttat tttaaatatt aactctaaag caggattact aaatttgatt     2400

aatctggtca atgagaatca aatggaaaca tatcattctg gaggtgcact tactcttcta     2460

caatgtggcc ggatcatttg tcattcctga ataggtcttt ctctcaacct gcaagagcta     2520

aaccatcttc aaaacataaa tcttgttcct ttctcattgg aagctttgaa aataatgata     2580

acactattag tagctagtag ttactaaagt gctaaagtaa ttgtggggtt tttctgtatt     2640

agcttatgaa ctgttgcttc tacttagccc ttttatagaa actctgagct gttactttgg     2700

ggaaattcca caatgtatta gcagccacaa atttccactg gtaaccaaag agtacctaag     2760

tagtttttca ttattttaag ttgaatttga ataaagattc cagaaataaa catggagctc     2820

agtattcagg aagcttaata ctgtttttga tctacaagat ccaaataatt atccctatct     2880

tcagaattaa cttagtctgt aatgtggctt caaaaaaaga aagccttttg acagctacat     2940

gacttacacc atacagaaca gtactggaca aaaggggtga tattttaaat ttactatccc     3000

agaaacaggg caacgttttt agaaacatct ttagcccaaa gtaactagta aaaataaatg     3060

gagtggtatc ctatcttctt tttttaagga atcaatgaat aataaatgta gatagacaat     3120

tttcttctgg tgagctgtct aaccctttgt acacattgac atttttaata tcgtaactga     3180

tttcttgatg ctagtttagc tatattagga aactgcttct acctagattg aaagaaattt     3240

gactcataaa cttccaagtt agaacaaata tttcttcatt attgttgctt ttatgtgagt     3300

agcatttccc tatcttgcag ttctgttaac atgaaaatgg catttttcca taatagcttt     3360

aaaataattt tttagtaatt attacaaaat taaggaaaat ctctattacc gttatctttt     3420

agcatttttt ttttcctcag tgatctcaag attgtcttag tctcaatgag atgtagctac     3480

aaaaatggca cctcttagca gtgatgaggc tcaggatatc ggatatcata acaccaatgt     3540

caggataaat atctcttcta aagacgatat ttacctttta caaggttaga aaagtctcat     3600

actacctcat ctttattgtg gcgcttttgt agatcactga gaagcttatc ttattaacca     3660

atataccact tcctaaatat ccatctttgg tgaaagaaaa tagtgtggta agagtaccca     3720

tgattatagt tttttatcag aatttgataa gattttctgt ttctgtgaaa caattatttt     3780

aaatattttt cttttaaaaa taacttttta tcagtacaga aaaacctaag ggatgactag     3840

cttacaaata ttctgttaag gggtagtttt ataaagaaaa atgatatata gttatgttgt     3900

cttttatagt gttaaaatta gtatttatat gaaagtcaag atctaagtac cttttcatat     3960

aattcaaact gattgcttgt gatatgtttt ctctggcttt tttatttttt caacttcaag     4020

gtattaacag ctgttaacac ttaaaaagta ctgccacata tgtagccttg aagtagttga     4080

tctaataaat gagagcaggg aggagattca ttgactctga aatgattttt atttttcctt     4140

tggtatttgc tacagtgaaa agaagtttgg aaagtagata cataaagact tgagaaggga     4200

attgtttaag ggaaaagaaa agagtaataa ttttttttaa aacattaagg aattggaatt     4260

cagaaaggtt acccccttcc tctgtgtctt tgtaaggata catttggaag aacatacagt     4320

attcagaaac taacctatat aaaatgtaaa caatatattg attgcactat ataaatgagt     4380

aaattttgag aggaacaatg tgggaatgta taaatttgtc taaaatttta taactgttga     4440

acaaagggaa gatttgaaca gtgtaaattc cagagttgag aaagcattta gcatggtgga     4500

aatgtggaga gcttattggt gagagaggat ggagctaaga gaaataagat caaatattaa     4560

aattaggaat ttaggcatta cctcagggaa aagccttgac agtgaaaaga aactacttaa     4620

tcgctaatag ctagtctgga ccagacactt aactgcgctt tgggaatcat cctgggctaa     4680

tcaggaaata aacttgactt ttctattttt ctctgaagct ttacaggaca tactcccact     4740

cccatttttt tctaagccta cagcatcttg attcatagta taattcctga agtatgctga     4800

atggactttt taaggttcct ttagcatttt tgtatagagt tatatgtgat ctttctataa     4860

ccatgccatt cacttaaata attcatgaag ggaatggttt aatttaaagg aagacctaat     4920

aggaagaaga ttaaaggaag cttttagtca gcctgtggct agatttattg atttggtgat     4980

caaacctgtg ctatttcctg aatttcagct aatggccaac tgtggtcaaa gaatggcttt     5040

cagttaaagt tttgacttct tattataaat aatataaaga atgtctcagt aattagaaat     5100

cccttaataa gtagaacaaa tgtggcaagt aggactccta tcggtataca aattccattt     5160

ctttttataa gaaaaacaca taaaccatta tcatttattc atgagccaaa gccattaaga     5220

agataaatcc agttatcagc ttcctgtctc tgaagtttgg atcattttat agatccacgc     5280

aatagagagc ttccttccta tgaaacaaaa accttgagat ctcttttttt ttgagacaga     5340

gtctcgctgt tgtcagccca ggctggagtg caatggcgca atctcggttc actgcaacct     5400

ctgccttcca ggttccagca attctcctac ctcagctccc aagtagctga gatgacaggc     5460

gtgtgccacc acgcccagct aatttttgta tttttagtag cgatggtgtt tcactacatt     5520

ggccaggctg gtctcgaact cctgacctca ggtgaccacc cgcctcagcc tcccaaagtg     5580

ctgggattac aggcatgagc cactgtgccc ggccaagatc taactcacgc ttacttttca     5640

ttaaaatatt tcttgtcgct tttagctatt gtcagaatcc aataaacagc ttacgcattc     5700

attttggtaa agcaaatttc acaggaaaat agacaaaatt ataagagatt cctggagaca     5760

acacaaggaa aacaatgttt aaaagcaaaa tagcctgtgt aatgttaggt aatgtaatgc     5820

ccaagtgaat aaaagatttt tcgtcaagca aactactgtt tctactttgg gggaaaaaag     5880

tcagttttac atttgtaatt taaggaaaga acagaaagca caaaggtttt tcttttcttt     5940

attaatggcc tactagaaat gagcagtgca agagtctacc tgtactattc taatacagta     6000

agatattgga cacaaaatgg aggtaacttt ttaaaataga ttggcttgga agttgaaatg     6060

tagattaatg gatataaccc aatagaaagg gattttcaaa taaaaccaaa gtctattttt     6120

ttatttactt tctaattttg aacagatgac tcagtcctaa atctttgcct ttatttccta     6180

taaaatgtag gtgatacttg taactcgact tcctggagtt aattcttcag caagaggtga     6240

ccctgggagc gtactttaaa ataattgctg tacagccatt gagtactaac atgatgatag     6300

gttttcaaaa tatctttgta gtggatgctg cataattaca ttcacttctc ttagactgta     6360

aaagactttc ttgacttgtt ttaacagtag agatagcagt acaatttgaa tttatggttt     6420

aggctctgca attagaggaa caattgcagt ttcctcctac ccttcatatg gtctgtgtaa     6480

aactgatgtt tgcttaactt attttaaaag ttgattacgt tttcagaaaa taaagataat     6540

cacttttgcc atggttataa tcaaatctaa gctttcagac ttgagagcca tggtgtaaaa     6600

ctcaaggagg tttatttaaa ttatgctgac tttgctagaa ttggataaat tctgtataag     6660

ccaagtatga gttcacatgt actcgaatat acagttttca caaagctatt actctcatca     6720

gtcaggcttg tatgatctat tccttaccac aaaagaagta gacaattgcc acttttattt     6780

ctaatcctta agttgaatgt ttcttcttgg atgtaagttc aaataaattg atctggataa     6840

attttcattt ctacttaatt aaaacttcct atgtaaaatc caaaaaaaaa aaaaaaaaaa     6900


<210>  2405
<211>  3557
<212>  DNA
<213>  homo sapiens

<400>  2405
agattgcgcg agggggagcg agcgagcggg cgctgccagg agcccgcagc cctggcgccc       60

gccgccgccc ggagccccgc aatatgccgc cgcggccctc tggctctagg ccatggcgag      120

gctctgccgg cgtgtcccct gcaccctgct tctcggcctg gccgtggtgc tgctgaaagc      180

gcggctggtc cccgcggccg ccagagcgga actcagccgc tccgacctca gcctcatcca      240

acagcagcag cagcagcagc aacaacaaca acaacagcaa aagcagctgg aggaggctga      300

ggaggagagg acagaggtgc ctggggcaac ctccaccttg acggttccag tgtctgtatt      360

tatgttgaaa gtccaggtga atgacatcat cagtcgtcag tacctgagcc aagcagttgt      420

agaagtgttt gtaaactaca cgaagacaaa ttccacagta actaaaagca atggagcagt      480

gctgataaaa gtaccctaca aattaggact tagtttaact attattgctt acaaagatgg      540

ctacgtgttg acccctctgc cttggaaaac cagaagaatg ccaatatatt catcagttac      600

actttcactg ttcccgcaaa gccaagcaaa tatatggcta tttgaagaca ctgttttaat      660

tactggaaaa ttagctgatg ccaagtctca accaagtgtt cagttttcaa aagccttaat      720

taaacttcct gacaaccatc atattagcaa cgttactggc tatcttacag ttctacaaca      780

gtttttgaaa gtggacaatt ttctgcatac aactggaatt actctcaata aaccaggttt      840

tgaaaacatt gaattgactc ctcttgctgc aatatgtgtg aaaatatatt ctggaggaaa      900

agaactaaag gtcaatggct ctattcaagt ttctcttcct cttctacgtc tgaatgatat      960

aagtgcaggg gatcgcatac ctgcttggac atttgatatg aacacaggtg cttgggtaaa     1020

tcatggtcgg ggaatggtca aggaacataa caatcattta atctggacat atgatgcacc     1080

acatttgggg tactggatag cagctccact tccaggaact agaggttcag gtataaatga     1140

agattccaag gacataactg cctaccacac agtgtttctt acagccatat taggaggaac     1200

aatagtcatt gtcattggat tttttgctgt actactttgt tattgcaggg acaagtgtgg     1260

tactccacag aaaagagaaa gaaatatcac taaacttgag gtcctcaaga gagaccagac     1320

aacttcaaca acacacataa atcatatcag tacagttaaa gttgcattaa aagctgagga     1380

caagtcgcag ttattcaatg ccaaaaactc ctcatatagt cctcagaaaa aggaaccatc     1440

aaaggcagaa acagaagaaa gagtttccat ggtaaaaact cgggacgatt ttaaaatcta     1500

caatgaagat gtttcatttc tatcagtcaa tcaaaataat tactcaagaa acccaacaca     1560

gtctttggag cccaatgtag ggtccaaaca acctaaacat attaacaaca atctatcttc     1620

atctctaggt gatgctcaag atgaaaagag gtatctcaca ggtaatgagg aggcgtatgg     1680

gcgttcccat attcctgaac agcttatgca tatttacagc caacccattg ccatccttca     1740

aacatctgac cttttctcca caccggaaca attacatact gctaagtcag ctactttgcc     1800

aagaaaggga cagttagtct atggccaatt gatggaacca gtaaatcgag agaactttac     1860

gcagaccttg cccaaaatgc caattcattc tcatgcacag cccccagatg ccagggaaga     1920

ggatatcata cttgaaggtc aacagagcct gccatcccag gcttcagatt ggagccgata     1980

ctcaagcagc ttactggaat ccgtctctgt tcctggaaca ctaaatgagg ctgttgtaat     2040

gactccattt tcatcggaac ttcaaggaat ttcagaacag accctcctgg agctgtccaa     2100

aggaaagccc tccccgcatc ccagagcctg gtttgtgtct cttgatggaa agccagttgc     2160

acaagtgagg cactccttta tagacctgaa aaagggcaag agaacccaga gcaatgacac     2220

cagtctggac tctggggtgg acatgaatga gcttcactca agtagaaagc tcgagaggga     2280

gaaaacattc atcaaaagca tgcatcagcc caagatcctt tacttagaag atttagacct     2340

aagcagcagt gagagtggaa ccaccgtctg ttcccctgag gacccagctt taaggcacat     2400

cctagatgga gggagtggag tgatcatgga gcaccctgga gaagagtcgc caggaaggaa     2460

aagcactgtt gaagattttg aagctaatac atcccccact aaaagaaggg gcagaccacc     2520

actagccaaa agagatagca agactaacat ctggaagaag cgagaggaac gcccactgat     2580

tcccataaat taactccaat ggggattgtg tgtctgctgt ctcgtgctgt ttattcttgc     2640

ttcttgttgt aaattgcagt acgaacttaa gaaaatgaga ctgagcaatc tcatggttct     2700

tggacatgtc tcaagcagag taaatggtaa ttcagtaatc agagagaaag ataccaagga     2760

atgctttttc tggcctattc atttattttt gggtgatgaa tttacagtat ctaagttttc     2820

aaaatgtaaa atagcttcaa gatgttagtt atctgaaaat gttgctcagc cagccagttt     2880

ggccttgact ctcttaagaa taacagtgaa atatatactc ctcaagttgc ctccaaaaat     2940

gttgcctcta ccatggtgac taccccatgg aacatttaga aacaaaactg acttcaggca     3000

tcatattatt ttaaatgtta ctattacgtc ttcttctgcc tatacttaaa aataacttga     3060

taaatgactt ggactgatgt tactctggag ttatcacaaa gaaaatgttg tttggtcttt     3120

aaagagcatg tgtattgtat catcccaaac gtaaatccta catttatata agatgggcaa     3180

gaagctactt ggtcattaga gagggagaca ccagctcttt ggttgttttt ggatataact     3240

ttacaaaata agtaagatgt taatttagaa atttgagaaa ttaatgctct aatactgagt     3300

ttttatttaa aaattatttt ttcttcccct caacaatgaa gcaagcttag ctgtcaaggg     3360

aaacttttta caaatctgaa aaaaacaatc tatgactttg gtttaaggct cactgatact     3420

tttaggctaa attggtttta atatatttct tctattctaa aaacctgaac tcagtcactt     3480

aaaggctatg aaatttaaaa aaaaagtcga tgtgaaagtt tcttttgaac actaaaataa     3540

aatatgtgca gataaaa                                                    3557


<210>  2406
<211>  5997
<212>  DNA
<213>  homo sapiens

<400>  2406
aaatatgagc ttgtgcttgc tggaggagga tgacagagga gcctgctgct gagttcactg       60

gtgctggggt taggtcactg ctgggctgaa gcgcactgac cataagagca acatgtgggc      120

aagagccgcg gcactggggt aatttattgc cgccgctcgc ttcaccagga accccacacg      180

ctgggttccc acaggatgcg acattcccac aggatgggac aactgcatgg aaacccacac      240

tcgggcctgt gttgagcaac cacgtttgag tccctggatg gccggttgca ggtgtcccat      300

cggaaggggc tccctcatgt catctactgc cgcctgtggc gatggccaga cctgcacagc      360

caccacgagc tacgggccat ggagctgtgt gagttcgcct tcaatatgaa gaaggacgag      420

gtctgcgtga atccctacca ctaccagaga gtagagacac cagttctacc tcctgtgttg      480

gtgccacgcc acacagagat cccggccgag ttccccccac tggacgacta cagccattcc      540

atccccgaaa acactaactt ccccgcaggc atcgagcccc agagcaatat tccagagacc      600

ccaccccctg gctacctgag tgaagatgga gaaaccagtg accaccagat gaaccacagc      660

atggacgcag gttctccaaa cctatccccg aatccgatgt ccccagcaca taataacttg      720

gacctgcagc cagttaccta ctgcgagccg gccttctggt gctccatctc ctactacgag      780

ctgaaccagc gcgtcgggga gacattccac gcctcgcagc catccatgac tgtggatggc      840

ttcaccgacc cctccaattc ggagcgcttc tgcctagggc tgctctccaa tgtcaacagg      900

aatgcagcag tggagctgac acggagacac atcggaagag gcgtgcggct ctactacatc      960

ggaggggagg tcttcgcaga gtgcctcagt gacagcgcta tttttgtcca gtctcccaac     1020

tgtaaccagc gctatggctg gcacccggcc accgtctgca agatcccacc aggatgcaac     1080

ctgaagatct tcaacaacca ggagttcgct gccctcctgg cccagtcggt caaccagggc     1140

tttgaggctg tctaccagtt gacccgaatg tgcaccatcc gcatgagctt cgtcaaaggc     1200

tggggagcgg agtacaggag acagactgtg accagtaccc cctgctggat tgagctgcac     1260

ctgaatgggc ctttgcagtg gcttgacaag gtcctcaccc agatgggctc cccaagcatc     1320

cgctgttcca gtgtgtctta gagacatcaa gtatggtagg ggagggcagg cttggggaaa     1380

atggccatgc aggaggtgga gaaaattgga actctactca acccattgtt gtcaaggaag     1440

aagaaatctt tctccctcaa ctgaaggggt gcacccacct gttttctgaa acacacgagc     1500

aaacccagag gtggatgtta tgaacagctg tgtctgccaa acacatttac cctttggccc     1560

cactttgaag ggcaagaaat ggcgtctgct ctggtggctt aagtgagcag aacaggtagt     1620

attacaccac cggccccctc cccccagact ctttttttga gtgacagctt tctgggatgt     1680

cacagtccaa ccagaaacac ccctctgtct aggactgcag tgtggagttc accttggaag     1740

ggcgttctag gtaggaagag cccgcagggc catgcagacc tcatgcccag ctctctgacg     1800

cttgtgacag tgcctcttcc agtgaacatt cccagcccag ccccgccccg ccccgcccca     1860

ccactccagc agaccttgcc ccttgtgagc tggatagact tgggatgggg agggagggag     1920

ttttgtctgt ctccctcccc tctcagaaca tactgattgg gaggtgcgtg ttcagcagaa     1980

cctgcacaca ggacagcggg aaaaatcgat gagcgccacc tctttaaaaa ctcacttacg     2040

tttgtccttt ttcactttga aaagttggaa ggatctgctg aggcccagtg catatgcaat     2100

gtatagtgtc tattatcaca ttaatctcaa agagattcga atgacggtaa gtgttctcat     2160

gaagcaggag gcccttgtcg tgggatggca tttggtctca ggcagcacca cactgggtgc     2220

gtctccagtc atctgtaaga gcttgctcca gattctgatg catacggcta tattggttta     2280

tgtagtcagt tgcattcatt aaatcaactt tatcatatgc tcttttaaat gtttggttta     2340

tatattttct ttaaaaatcc tgggctggca cattgactgg gaaacctgag tgagacccag     2400

caactgcttc tctcccttct ctctcctgag gtgaagcttt tccaggtttt gttgaagaga     2460

tacctgccag cacttctgca agctgaaatt tacagaagca aattcaccag aagggaaaca     2520

tctcaggcca acataggcaa atgaaaaggg ctattaaaat atttttacac ctttgaaaat     2580

tgcaggcttg gtacaaagag gtctgtcatc ttccccctgg gatataagat gatctagctc     2640

ccggtagagg atcaccggtg acaactatag cagttgtatt gtgtaacaag tactgctccc     2700

agcagcaatt agggagaaaa ctagtctaaa ttatttcaac tggaaaaaag aaaaaagagt     2760

cctcttcttt tcccagcctt ttgcagaaca cagtagacag aactgccacc ttcaattggt     2820

actttattct ttgctgctgt ttttgtataa aatgacctat cccacgtttt tgcatgaatt     2880

tatagcagga aaaatcaagg gatttcctat ggaagtcctg ctttattcca ggtgaaggga     2940

aggaagtgta tatacttttg gcaagtcata cagctcaaat gtgatgagat ttctgatgtt     3000

agagggagat ggagaggctt cctgatgcct catctgcagg gtcctgtgcc tctgaagttc     3060

tagccatgag gtttccaggt aggacagctg ctccccaagc ctcctgagga cacaggaaga     3120

gacggaagga gcaccttgac agacttgtgt gagtcttctc gaaggagggt tgactcagaa     3180

cccagagaca atacaaaacc cctcacttcc tctgagaggg ccaaatgctg tgagtctgaa     3240

gtatgtgcct ggtgtgaaat gatctatggc ctgtttctta cacaggaagc cccctgaacc     3300

tcctgtacat gtgttcatgt tcccagccag ctctgagacc caggaaccaa atattccatt     3360

ttggcttctg ctagagcagt catggttcct ctcctaaaag ccatgggcag cagtttccga     3420

gggcctgcat gatccacctg ctgcacgatc ctatgagggc ttcctgtggc acacagccct     3480

ctgggtgctt gggaactagc ttcaggcaca gcctgattct ggtgatccag tgatctatgg     3540

aagtcgtgtc ttactccagg tgaaggggga aaaaaaaagc ctatactttg gcaggttatg     3600

aactttgaat gtgatgaaat gacacgtttg gctgcatttg gatggtgtct tagaaccctc     3660

attgctcaga cctgaaggct acttctagga gcatgaagtt tgagttttgt gtttttccaa     3720

aggatacttc cttggccctt tttctttatt gactagacca ccagaggagg atgtgtggga     3780

ttgtaggcaa acccacctgt ggcatcactg aaaataaatt tgatcatacc taagaggtta     3840

ggaaatggtg ccattcccac cttagagtgc tacataggtg ctttgggcgt atgtaacatt     3900

agtgtccttc cttgaagcca caagctagtt ttcttagttt taaaatcctg ttgtatgaat     3960

ggcatttgta tattaaaaca cttttttaaa ggacagttga aaagggcaag aggaaaccag     4020

ggcagttcta gaggagtgct ggtgactgga tagcagtttt aagtggcgtt cacctagtca     4080

acacgaccgc gtgtgttgcc cctgccctgg gctccccgcc atgacatctt caccttgcag     4140

cttgtgctga gactgaccca agtgcagcta gcactgggac acagatcctt gtcttcagca     4200

ccttccaagg agccaacttt tattcccttt cctctctccc ctccccacct cgcttcttcc     4260

caatttagta acttagatgc ttccagcaca tacgtaggta gctaccccag ccggtttgga     4320

ttacaggcct gtgctggaac atcatctcag ttggccacct tcctggcagg ctgtagacct     4380

gacattttga gacaagccta gagtcaggag cagggacttt gactcttagg aagagcacac     4440

atgagggcaa ggctgctggc agacgtctcc attgtcctta tgttgtctgt gttgtatttt     4500

ttttttttta ttgaccatgg tgattatttt tttaaaccat cgttaatata ctgaagtgag     4560

ctatagcaca tatcatgtgc ttagtttgtt tatttttctc catctcccct tggcttccta     4620

gagtttggac atattccagg ctaaatgctt ttactcaaga ctacagaaag gtttgaagta     4680

gtgtgtgcat ggcatgcacg tatgtaagta atctggggaa gaagcaaaga tctgtttcat     4740

tcttagcctc aggcctcatg agggtctcca cagggccgga gctcaggtta caccactcct     4800

tcgtccttac aggagatgta gggagaagaa tctgcaggct gcttgtagga ctgttcacca     4860

agggggatac cagcagcaag agagtgcacc cgtttagccc tggaccctgt ttcttactgt     4920

gtgacttggc tagagttggg agttccccca aaataaacgt gtccccattt taccagaacc     4980

aaacctcaac acagcgaagc tgtactgtct ttgtgtggca aagatgttcc cttgtaggcc     5040

cctttcaggt aaccgtcttc acaatgtatt ttcatcacag tttaaggagc atcagccgct     5100

tctcaagtgg gtagggaaag cagaaaaacg tacgcaagag gacatggatc caaaatgatg     5160

atgaagcatc tcccatgggg aggtgatggt ggggagatga tgggctaaac aggcaacttt     5220

tcaaaaacac agctatcata gaaaagaaac ttgcctcatg taaactggat tgagaaattc     5280

tcagtgattc tgcaatggat ttttttttaa tgcagaagta atgtatactc tagtattctg     5340

gtgtttttat atttatgtaa taatttctta aaaccattca gacagataac tatttaattt     5400

tttttaagaa agttggaaag gtctctcctc ccaaggacag tggctggaag agttggggca     5460

cagccagttc tgaatgttgg tggagggtgt agtggctttt tggctcagca tccagaaaca     5520

ccaaaccagg ctggctaaac aagtggccgc gtgtaaaaac agacagctct gagtcaaatc     5580

tgggcccttc cacaagggtc ctctgaacca agccccactc ccttgctagg ggtgaaagca     5640

ttacagagag atggagccat ctatccaaga agccttcact caccttcact gctgctgttg     5700

caactcggct gttctggact ctgatgtgtg tggagggatg gggaatagaa cattgactgt     5760

gttgattacc ttcactattc ggccagcctg accttttaat aactttgtaa aaagcatgta     5820

tgtatttata gtgttttaga tttttctaac ttttatatct taaaagcaga gcacctgttt     5880

aagcattgta cccctattgt taaagatttg tgtcctctca ttccctctct tcctcttgta     5940

agtgcccttc taataaactt ttcatggaaa agctcctgtg ccaggagctc agtctga        5997


<210>  2407
<211>  2143
<212>  DNA
<213>  homo sapiens

<400>  2407
actgaaggct agagaacaat tccgagaaag agacggagag agagggaaga aaaagacaga       60

tagatagata ttggggggaa ggagaaaaaa ggagaagaga gggaagagag gacagcggag      120

agagagcacc agagagagag ggagagagag agagagcgct agagagaggg agcgagcatg      180

tgcgatgagc aatagctgtg gaccttacag ttgctgctaa ctgccctggt gtgtgtgagg      240

gagagagagg gagggaggga gagagagcgc gctagcgcga gagagcgagt gagcaagcga      300

gcagaaaaga ggtggagagg gggggaataa gaaagagaga gaaggaaagg agagaaggca      360

ggaagaaggc aagggacgag acaaccatgc tgtgctgtat gagaagaacc aaacagaatt      420

aaaagggaac ctggtctctg ggttgttttc aacatctcaa gtgtgaattt tccctgtcaa      480

aatcttcaca aggaaaatga gtcacagcat cacctgggtg acgaggtcat aacacctcag      540

cccttgctta aaaaatttta tttctacttt tctattgtaa agagatctca aaacaggaag      600

ataaaattgg actgacagct ctacagccta gtcttttaga cagtgaacta ggccagcatt      660

ggcagacact ggcgatgaca aagtcctgct ctgaattatg ccaccccgca ctccactttt      720

taccttgcct gggaggcttg aggaaaaatc ttcagagagc agttcgacct agtccttatt      780

cacttggctt cttgactttc tggatttcaa gggttgaaaa aaatgatgac gaccaaaaga      840

ttgaacaaga tggtatcaaa ccagaagata aagctcataa ggccgcaacc aaaattcagg      900

ctagcttccg tggacacata acaaggaaaa agctcaaagg agagaagaag gatgatgtcc      960

aagctgctga ggctgaagct aataagaagg atgaagcccc tgttgccgat ggggtggaga     1020

agaagggaga aggcaccact actgccgaag cagccccagc cactggctcc aagcctgatg     1080

agcccggcaa agcaggagaa actccttccg aggagaagaa gggggagggt gatgctgcca     1140

cagagcaggc agccccccag gctcctgcat cctcagagga gaaggccggc tcagctgaga     1200

cagaaagtgc cactaaagct tccactgata actcgccgtc ctccaaggct gaagatgccc     1260

cagccaagga ggagcctaaa caagccgatg tgcctgctgc tgtcactgct gctgctgcca     1320

ccacccctgc cgcagaggat gctgctgcca aggcaacagc ccagcctcca acggagactg     1380

gggagagcag ccaagctgaa gagaacatag aagctgtaga tgaaaccaaa cctaaggaaa     1440

gtgcccggca ggacgagggt aaagaagagg aacctgaggc tgaccaagaa catgcctgaa     1500

ctctaagaaa tggctttcca catccccacc ctcccctctc ctgagcctgt ctctccctac     1560

cctcttctca gctccactct gaagtccctt cctgtcctgc tcacgtctgt gagtctgtcc     1620

tttcccaccc actagccctc tttctctctg tgtggcaaac atttaaaaaa aaaaaaaaaa     1680

agcaggaaag atcccaagtc aaacagtgtg gcttaaacat tttttgtttc ttggtgttgt     1740

tatggcaagt ttttggtaat gatgattcaa tcattttggg aaattcttgc actgtatcca     1800

agttatttga tctggtgcgt gtggccctgt gggagtccac tttcctctct ctctctctct     1860

ctgttccaag tgtgtgtgca atgttccgtt catctgagga gtccaaaata tcgagtgaat     1920

tcaaaatcat ttttgttttc ctccttttca atgtgatgga atgaacaaaa aggaaaaaat     1980

tcaaaaaacc cagtttgttt taaaaataaa taaataaagc aaatgtgcca attagcgtaa     2040

acttgcggct ctaaggctcc tttttcaacc cgaatattaa taaatcatga gagtaatcaa     2100

ggtcaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa                       2143


<210>  2408
<211>  1280
<212>  DNA
<213>  homo sapiens

<400>  2408
ccgctgttat acgtcacttc cacggctcag cgtcaggcaa gttggcctct ctgttgtaaa       60

ttagtggtta aggttatcta ttattgccac ttttccagcg ctaaaggctg ttttggaacc      120

agtgttgctt gttccgcggg tgattggctt ttttttttgg caaaccagtt attcaagttt      180

ctggtcttta aaaaactctg tggcggtacg gtaaccgagg aggttccagc gcggcggaag      240

taccccgcgg gtgggtgtgt gcgcaaggcc agggccagag gggcacgtgg cgccgggagg      300

agagagaatg tcttttcgag gcggaggtcg tggaggcttt aatcgaggtg gtggaggtgg      360

cggcttcaac cgaggtggca gcagcaacca cttccgaggt ggaggcggcg gtggaggcgg      420

cggcaatttc agaggcggcg gcaggggagg atttggacga gggggtggcc gcggaggctt      480

taacaaaggc caagaccaag gacctccaga acgtgtagtc ttattaggag agttcctgca      540

tccctgtgaa gatgacatag tttgtaaatg taccacagat gaaaataagg tgccttattt      600

caatgctcct gtttacttag aaaacaaaga acaaattgga aaagtggatg aaatatttgg      660

acaactcaga gatttttatt tttcagttaa gttgtcagaa aacatgaagg cttcatcctt      720

taaaaaacta cagaagtttt atatagaccc atataagctg ctgccactgc agaggttttt      780

acctcgacct ccaggtgaga aaggacctcc aagaggtggt ggcaggggag gccgaggagg      840

aggaagagga ggaggtggca gaggtggtgg cagaggcggt ggttttagag gtggaagagg      900

aggtggaggt gggggcttca gaggaggaag aggtggtggt ttcagaggga gaggacatta      960

agtgaaacag ttgacagaca tcaccagttg acttctgcat taacctgcat gatctgtttc     1020

tactatggat tggaaacttg tttcttgaac aagtcttgaa gatcttggtc attttatgac     1080

aatggatcta aaatgtcagc atcatgcaaa gtgcaacgga atagtgaatt ttgctctaaa     1140

agagcatgaa caagtctttc taatgttttg tacagtgcct ggcactctgt gggtgctcaa     1200

taaatggata ggagttttca tttgaagcat atttgaattt ttaaaataaa gtgttttatt     1260

cccttaaaaa aaaaaaaaaa                                                 1280


<210>  2409
<211>  3133
<212>  DNA
<213>  homo sapiens

<400>  2409
aaacagtcag ttatagtggg ttcaccagac tgttggagat ttgtgccata ggagctgtgc       60

atgcatgatg aagtggcaca gccactgaac ctatcagcta aacccaagac ctctgatggc      120

aaatcaccca catcacccac ctctccccat atgccagctc tgagaataaa cagtggggca      180

ggccccctca aagcctctgt cccagcagcg ttagctagtc cttcagccag agttagcaca      240

ataggttact taaatgacca tgatgctgtc accaaggcaa tccaagaagc tcggcaaatg      300

aaggagcaac tccgacggga acaacaggtg cttgatggga aggtggctgt tgtgaatagt      360

ctgggtctca ataactgccg aacagaaaag gaaaaaacaa cactggagag tctgactcag      420

caactggcag ttaaacagaa tgaagaagga aaatttagcc atgcaatgat ggatttcaat      480

ctgagtggag attctgatgg aagtgctgga gtctcagagt caagaattta tagggaatcc      540

cgagggcgtg gtagcaatga accccacata aagcgtccaa tgaatgcctt catggtgtgg      600

gctaaagatg aacggagaaa gatccttcaa gcctttcctg acatgcacaa ctccaacatc      660

agcaagatat tgggatctcg ctggaaagct atgacaaacc tagagaaaca gccatattat      720

gaggagcaag cccgtctcag caagcagcac ctggagaagt accctgacta taagtacaag      780

cccaggccaa agcgcacctg cctggtggat ggcaaaaagc tgcgcattgg tgaatacaag      840

gcaatcatgc gcaacaggcg gcaggaaatg cggcagtact tcaatgttgg gcaacaagca      900

cagatcccca ttgccactgc tggtgttgtg taccctggag ccatcgccat ggctgggatg      960

ccctcccctc acctgccctc ggagcactca agcgtgtcta gcagcccaga gcctgggatg     1020

cctgttatcc agagcactta cggtgtgaaa ggagaggagc cacatatcaa agaagagata     1080

caggccgagg acatcaatgg agaaatttat gatgagtacg acgaggaaga ggatgatcca     1140

gatgtagatt atgggagtga cagtgaaaac catattgcag gacaagccaa ctgataaggg     1200

tcaaaagatt gttgtgacct taggacttaa agaagcccta actggttcat ccttaccagt     1260

ggccaagcac attaactttc tcatacactg actgttactt taactgttag tcttaaatag     1320

ttgggacatc agctgactaa tagacctcag cctcaaaagg cttggaaaga aaaaacaaat     1380

acaacaagca aacaacaata tcaacaacaa gagattgaaa taagctatgg gtaaaataat     1440

gccagtaatt cagctgctac atccaagcac tgaagtctta cccgtcaact tttttttttt     1500

tttaaataaa ctttatggct gtttgttcta caatgttcta gaaattctca ctcaggtaca     1560

cagtgccaac aagtggcttg tgaatgtgtt ttgttgtttt gtgctacaat ttttaaaaag     1620

aaaaaagttt tgttttgttt tttggggttt ctgggttttt tccttttctt tttctttcct     1680

ttcatttttt ttctttgtaa tgcacctgac agaaaaaaaa gaaaaatgaa tttctcttta     1740

cttctctcca ccttctccat ctctctactt taaagatgga agtctgtgca tgaggggaaa     1800

gagggaaaaa gagcctgttt ttaacttcct tgctatccac cacaaaataa gcaattattt     1860

tctttagagg actttatcta ttgcacacca cactacatct ttgagcaagt gccaaatttg     1920

tactgaagtg ttgaccaagt tcattttttc tctttacttt ttccttttcc ttcttaagtt     1980

aggacagtgt taaatcttag acaatccctt gaaaaacctg aaataccagc agctggtgag     2040

atttgacttt tttttttaat ggaaactgta ggtgctgttc tcaggtgaaa agagagagag     2100

agagagagac ataagaaatt tagagaaaaa tattttctga tcttggattt ttgtgtgtat     2160

gtatgtatgt gattatggta ctaataatag gaataacgtt ggaccattgt gagttaaacc     2220

cacatctggg gatgaaatcc cacatcctcc caagtgactg gtctagaaat aatcttgacc     2280

ttgactttgc acttcaaatg acaacttaac caagtatagg gctcagaaat tatattttta     2340

aatgtctgat tattattgga tggatcaggt ggccctgtgt aatagaggtg tgcatgtata     2400

acatggaagc tactagcaaa ctgctcccag atgtcctttc tccctggtca gttggttcca     2460

ttaacgtttg ctacttagtg atttttgttt ttcctgttga tattttgagc aaaacaatca     2520

ttgttttcat tgaatatatt tggccatttt ttcagacaaa tagaattagc ttatttcttc     2580

aacattccat cctttcccga tcaggaaatg aaactgatga ttttataagg tatttttcac     2640

ccctccatga agtgaggtgg aggcctttag catttcagaa gtgtgggcca tatgtagttc     2700

atgccataaa aagtaggatt taattaaaag tcattgcagc ccaataaaat ggagcctggc     2760

tgcacccagg gatccttgcc actgctcttc ccttgctgtc agattaatcc actgaagtcc     2820

aactttggtt caagcagagt atttgcaaag agcaacaact gaatgtgatg ggactgctta     2880

tgtagatttt gccagccaaa tgccaaggca gttgtagggc ctgtacaaat aaatgcaaaa     2940

tcatttcaag tcaattgcca ttatttgtat tgaagtatca gatagatagt aaatactgca     3000

actagtagct tgatgtgcta tagttttcac tccagtcatc attttcctat ctcacccccc     3060

gaaacaccac cctaaagttg gatttttaca tataaataaa aaaagaatcc cttttaaaaa     3120

aaaaaaaaaa aaa                                                        3133


<210>  2410
<211>  4301
<212>  DNA
<213>  homo sapiens

<400>  2410
tagagaacgt ggctcccgcg ggggcgctcg gagccgccgc acaggtagcg agagcgcggc       60

gccttctcct tcctttgtga gccgccgggc agggcaccga cctcgggttc tcccggcgcc      120

tccactgcag ggatctctag cctcgcacct cctcccctcg tcgcctgccc accctctgct      180

cctctcctgg cgccggggac cctgcccctt tgcgcctttt cctggctctg cctcggcttc      240

catttttctc tgcttccgaa aagccagtgg ggaagggcgg gggagacctg ccagtcctcc      300

cagacttctc ccgggttgct ccagctggcc ctcctcgccc cttcccggga gaggcacatg      360

gagagacatg aatcagggga gtggactgga cctgctgaag atctcatatg gaaaaggagc      420

cagaaggaaa aacagattta aaggatctga tggaagcacg tcatctgata ctacctcaaa      480

tagttttgtt cgccagggtt cggcagactc ctacactagc cgtccatccg attccgatgt      540

atctctggag gaggaccggg aggcagtgcg cagagaagcg gagcggcagg cccaggcaca      600

gttggaaaaa gcaaagacaa agcccgttgc atttgcggtt cggacaaatg tcagctacag      660

tgcggcccat gaagatgatg ttccagtgcc tggcatggcc atctcattcg aagcaaaaga      720

ttttctgcat gttaaggaaa aatttaacaa tgactggtgg atagggcgat tggtaaaaga      780

aggctgtgaa atcggattca ttccaagccc agtcaaacta gaaaacatga ggctgcagca      840

tgaacagaga gccaagcaag ggaaattcta ctccagtaaa tcaggaggaa attcatcatc      900

cagtttgggt gacatagtac ctagttccag aaaatcaaca cctccatcat ctgctataga      960

catagatgct actggcttag atgcagaaga aaatgatatt ccagcaaacc accgctcccc     1020

taaacccagt gcaaacagtg taacgtcacc ccactccaaa gagaaaagaa tgcccttctt     1080

taagaagaca gagcacactc ctccgtatga tgtggtacct tccatgcgac cagtggtcct     1140

agtgggccct tctctgaagg gctacgaggt cacagatatg atgcaaaaag cgctgtttga     1200

ttttttaaaa cacagatttg aagggcggat atccatcaca agggtcaccg ctgacatctc     1260

gcttgccaaa cgctcggtat taaacaatcc cagtaagcac gcaataatag aaagatccaa     1320

cacaaggtca agcttagcgg aagttcagag tgaaatcgaa aggatttttg aacttgcaag     1380

aacattgcag ttggtggtcc ttgacgcgga tacaattaat catccagctc aactcagtaa     1440

aacctccttg gcccctatta tagtatatgt aaagatttct tctcctaagg ttttacaaag     1500

gttaataaaa tctcgaggga aatctcaagc taaacacctc aacgtccaga tggtagcagc     1560

tgataaactg gctcagtgtc ctccagagct gttcgatgtg atcttggatg agaaccagct     1620

tgaggatgcc tgtgagcacc ttgccgacta tctggaggcc tactggaagg ccacccatcc     1680

tcccagcagt agcctcccca accctctcct tagccgtaca ttagccactt caagtctgcc     1740

tcttagcccc accctagcct ctaattcaca gggttctcaa ggtgatcaga ggactgatcg     1800

ctccgctcct atccgttctg cttcccaagc tgaagaagaa cctagtgtgg aaccagtcaa     1860

gaaatcccag caccgctctt cctcctcagc cccacaccac aaccatcgca gtgggacaag     1920

tcgcggcctc tccaggcaag agacatttga ctcggaaacc caggagagtc gagactctgc     1980

ctacgtagag ccaaaggaag attattccca tgaccacgtg gaccactatg cctcacaccg     2040

tgaccacaac cacagagacg agacccacgg gagcagtgac cacagacaca gggagtcccg     2100

gcaccgttcc cgggacgtgg atcgagagca ggaccacaac gagtgcaaca agcagcgcag     2160

ccgtcataaa tccaaggatc gctactgtga aaaggatgga gaagtgatat caaaaaaacg     2220

gaatgaggct ggggagtgga acagggatgt ttacatccgc caatgagttt tgcccgtttg     2280

tgtttttttt tttttttttt tgaagtcttg tataactaac agcatcccca aaacaaagtc     2340

tttggggtct acactgcaat catatgtgat ctgtcttgta atattttgta ttattgctgt     2400

tgcttgaata gcaatagcat ggatagagta ttgagatact ttttcttttg taagtgctac     2460

ataaattggc ctggtatggc tgcagtcctc cggttgcata ctggactctt caaaaactgt     2520

tttgggtagc tgccacttga acaaaatctg ttgccaccca ggtgatgtta gtgttttaag     2580

aaatgtagtt gatgtatcca acaagccaga atcagcacag ataaaaagtg gaatttcttg     2640

tttctccaga tttttaatac gttaatacgc aggcatctga tttgcatatt cattcatgga     2700

ccactgtttc ttgcttgtac ctctggctga ctaaatttgg ggacagattc agtcttgcct     2760

tacacaaagg ggatcataaa gttagaatct attttctatg tactagtact gtgtactgta     2820

tagacagttt gtaaatgtta tttctgcaaa caaacacctt cttattatat atataatata     2880

tatatatatc agtttgatca cactatttta gagtcttaat gccaagtcag cagatttgct     2940

ttatgaatta cagggactag aaatgcccac attcaggaaa tttgtaataa cattgtctag     3000

acacctatcc tcattctagt agaaagtgtg tacatactgt aaatatgtgt gattgcttga     3060

cttgaaaagg tttgaattct gaatgttata ccatccttgt aagtaagttt gtaatttcca     3120

ccataaatta tggtaaatat aaaactccag aggttgttct actccataca gttcacactg     3180

attgtgacac attcttagta gctagtgtct gttctagtca ctgcactgga gtctacgagc     3240

cggaactcgc tatatgcacg tgtgtgtgtc cgtatgtaag aaagtgtgca ccgagtgact     3300

gaatggttga gatgaattgg aatgctgaag actaacgaag aaactagaga ctgatatcga     3360

gcattctgcc cacctcgctc tgtatttaat taattgtgct atatgttgct ttaacaaccc     3420

attgagcagt cagggaatgt gagtaagctt gctgccaaag gtaactagga aagcattcat     3480

ctgctgcctc cttgtttttg ctcctagaga gtgaaaatac aggcaatttt actgtgagtg     3540

tttcactgga aatgtacaat ctttgtgtgt tagagtattt gttttagtaa gaaatgttta     3600

cacagcttgt ggaattattt cgtgggaaaa taaattttta taacttctcc cacttcaatt     3660

tctaaccttg cctattgttc ctgttgtttg tttacctccc agttacctac cattcctccc     3720

caccaccgac tccagcaggt tcactgtctg tcagaaccca gaagtgcttc ttataaccaa     3780

agtttctgtt cttcagaaga aatcagggca aaatggggtg acttgaagtg aataaaatgt     3840

taagaatatt atcctacata agacatgtac acagaagggg aaccttgaag acattatctc     3900

catgcctcaa ttacactgct gtaagaagct tacaatgtca tcatgtttaa ggctaagacc     3960

ttttccgtgt ctcaagtgta tattttgtcc agttataact ggatggtaag acagtattaa     4020

gagtgcaagt acctggcact tgaagtttgt cccaggaaaa tgcctgtgta taattaccta     4080

acttcagatc tgcacattaa cttatttaac aaaataaatc agccgggcgc agtggctcat     4140

gcctgtaatc ccagcaattt gggaggctga ggagggtgga tcacctgagg tcaggagttc     4200

aagaccagcc tggccaacgt ggcgaaaccc cgtctctact aaaaagataa aaaattagcc     4260

aggtgtggtg gtgcacacct gtaatcccag ctacttggga g                         4301


<210>  2411
<211>  2610
<212>  DNA
<213>  homo sapiens

<400>  2411
ctgagctgag tgacaggaag acggttcaat gggcggcgcg gaggcggagc cgtgggggcg       60

ggctcccggt cccgctatcg gcggccggcg ggcaggcgac tcctgtcccg ggtggaggcg      120

gcggagccgg agccggggga gggggcagcg gctgtctcac ggaccacggc ggcgcccgca      180

gctcctcacc gcagcacccc cactgcaggc ccgaggagct ttccggagct tcccacactc      240

ctggggagaa gacttcttag ccagcttgat gtttaaaatt cagctggagc ccttaaaact      300

tcgagcgtgg acgctgaatg ggtttgtaaa gtttcgaaac aaggagacca gtgctggtcc      360

agtggctgtg atgggaaaag attattacaa gattcttggg atcccatcgg gggccaacga      420

ggatgagatc aagaaagcct accggaagat ggccttgaag taccacccag acaagaataa      480

agaacccaac gctgaggaga agtttaagga gattgcagag gcctatgatg tgctaagtga      540

ccccaagaaa cggggcctgt atgaccagta tggggaggaa ggcctgaaga ccggcggtgg      600

cacatcaggt ggctccagtg gctcctttca ctacaccttt catggggacc cccatgccac      660

ctttgcctcc ttctttggtg gctccaaccc cttcgatatc ttctttgcca gcagccgctc      720

cactcggccc ttcagtggct ttgacccaga tgacatggat gtggatgaag atgaggaccc      780

atttggcgct ttcggccgtt ttggcttcaa tgggctgagt aggggtccaa ggcgagcccc      840

agaaccactg taccctcggc gcaaggtgca ggacccccca gtggtgcacg agctgcgggt      900

gtccctggag gagatctacc atggctccac caagcgcatg aagatcacaa ggcgtcgcct      960

caaccctgat gggcgaactg tgcgcaccga ggacaagatc ctgcacatag tcatcaagcg     1020

tggctggaag gaaggcacca agatcacctt ccccaaagaa ggcgacgcca cacctgacaa     1080

catccctgct gacatcgtct ttgtgctcaa agacaagccc catgcacact tccgccgaga     1140

tggcaccaac gtgctctaca gtgccctgat cagcctcaag gaggcgctgt gtggctgcac     1200

tgtgaacatt cccactatcg acggccgagt gatccctttg ccctgcaatg atgtcatcaa     1260

gccaggcacc gtgaagagac tccgtgggga gggccttccc ttccccaaag tgccaactca     1320

gcgaggagac ctcattgttg agttcaaagt tcgcttccca gacagattaa caccacagac     1380

aagacagatc cttaagcagc acctaccctg ttcctaggct ctgccccagc cagtccagag     1440

cctaccacag caataccccc aacactcact ccactcaatg tgcacccagc ttgatgtcca     1500

ctggacactg gcaacttttt ctaaaatgca aaaaaaagcc actggttttc aggaaaatgt     1560

tcctgtccct gacccctttt agagctgggc tgcctggggg gagtgggagg gaggtgggga     1620

gagctagccc aggccagggg tcaatgttca tgtcactagc tttcaatcca gtttccactg     1680

cagtggctgg agagtgacct gagtgctact tgaagatatg tagagattcc ttatccatgc     1740

ctgtacatag catgtcctcc tcccctcagc tttgctaata ccagtcccct cccttccctt     1800

tggcttcctg ctgttggggg tggaaaagac tagaaaggac attgctttct cagccccacc     1860

cccaggtcca cagtgtccaa ggtaatggca cacatattca tgcacaagaa gcactcacct     1920

agagctgtct gtgcctctct gggagaaagg agagaggata agaagggaaa gttcacaacc     1980

tgtgaacagg gacttgagca cgagacactt ttcatctgga gcaggggggt gagctcctca     2040

gcagcctccg taacagctgc cctgcctaca cctgcagagc tggaggttct gtcctccctg     2100

ctgctctcag gagtgttcaa gggtggaggg cagggaatgg ggcctgaggt attaaggcta     2160

agaggtgggg gacagggccc atctaccagc cttcatcagg aagggaaagg gctttggggt     2220

caggtggcag ctattcccca ccaagagatt cagggtcaca ggtttttccc cacacctctg     2280

aactcagggc ctagccaccc ccaaacttcc aaatcccact tttgtgatat gtgaagctac     2340

tcatttctta cccttggagg ctgtgtgggg aatttccagc ccttttatgc ctgtgtgatc     2400

ccaccccacc cccatagttg tataaaggtc atagtgaaga agctggggga agactgcttc     2460

agccagatcc tggggtgggg tctttaggtt ttctcacttt gacaaccccc gaatgttttt     2520

atagtagttt ttttgtattt ttttgtaatg acagtattat gtaaaaaata aagtatttta     2580

aaaatatggc aaaaaaaaaa aaaaaaaaaa                                      2610


<210>  2412
<211>  3326
<212>  DNA
<213>  homo sapiens

<400>  2412
aataaatttc tctgtgattg gttggtgaag gttttcaaac cggagctgtg ggcgcggcgc       60

tgctctgccg ttgggtgagg cgcggagcga agtgaagggt ggcccaggtg gggccaggct      120

gactgaatgt atctcctagc tatggactaa ataatacatg gggggaaata aacaagtatt      180

catgagggtg aaaatgtgac ccagcaggaa aattacaact attttcaatt gacgttgaat      240

agggagagcc aaaggaaatc aacatttgaa ttgactaccc aatgtcctgc ccctgtttct      300

gtcctgtagc acttaggaaa gatggatact atgatgctga atgtgcggaa tctgtttgag      360

cagcttgtgc gccgggtgga gattctcagt gaaggaaatg aagtccaatt tatccagttg      420

gcgaaggact ttgaggattt ccgtaaaaag tggcagagga ctgaccatga gctggggaaa      480

tacaaggatc ttttgatgaa agcagagact gagcgaagtg ctctggatgt taagctgaag      540

catgcacgta atcaggtgga tgtagagatc aaacggagac agagagctga ggctgactgc      600

gaaaagctgg aacgacagat tcagctgatt cgagagatgc tcatgtgtga cacatctggc      660

agcattcaac taagcgagga gcaaaaatca gctctggctt ttctcaacag aggccaacca      720

tccagcagca atgctgggaa caaaagacta tcaaccattg atgaatctgg ttccatttta      780

tcagatatca gctttgacaa gactgatgaa tcactggatt gggactcttc tttggtgaag      840

actttcaaac tgaagaagag agaaaagagg cgctctacta gccgacagtt tgttgatggt      900

ccccctggac ctgtaaagaa aactcgttcc attggctctg cagtagacca ggggaatgaa      960

tccatagttg caaaaactac agtgactgtt cccaatgatg gcgggcccat cgaagctgtg     1020

tccactattg agactgtgcc atattggacc aggagccgaa ggaaaacagg tactttacaa     1080

ccttggaaca gtgactccac cctgaacagc aggcagctgg agccaagaac tgagacagac     1140

agtgtgggca cgccacagag taatggaggg atgcgcctgc atgactttgt ttctaagacg     1200

gttattaaac ctgaatcctg tgttccatgt ggaaagcgga taaaatttgg caaattatct     1260

ctgaagtgtc gagactgtcg tgtggtctct catccagaat gtcgggaccg ctgtcccctt     1320

ccctgcattc ctaccctgat aggaacacct gtcaagattg gagagggaat gctggcagac     1380

tttgtgtccc agacttctcc aatgatcccc tccattgttg tgcattgtgt aaatgagatt     1440

gagcaaagag gtctgactga gacaggcctg tataggatct ctggctgtga ccgcacagta     1500

aaagagctga aagagaaatt cctcagagtg aaaactgtac ccctcctcag caaagtggat     1560

gatatccatg ctatctgtag ccttctaaaa gactttcttc gaaacctcaa agaacctctt     1620

ctgacctttc gccttaacag agcctttatg gaagcagcag aaatcacaga tgaagacaac     1680

agcatagctg ccatgtacca agctgttggt gaactgcccc aggccaacag ggacacatta     1740

gctttcctca tgattcactt gcagagagtg gctcagagtc cacatactaa aatggatgtt     1800

gccaatctgg ctaaagtctt tggccctaca atagtggccc atgctgtgcc caatccagac     1860

ccagtgacaa tgttacagga catcaagcgt caacccaagg tggttgagcg cctgctttcc     1920

ttgcctctgg agtattggag tcagttcatg atggtggagc aagagaacat tgacccccta     1980

catgtcattg aaaactcaaa tgccttttca acaccacaga caccagatat taaagtgagt     2040

ttactgggac ctgtgaccac tcctgaacat cagcttctca agactccttc atctagttcc     2100

ctgtcacaga gagtccgttc caccctcacc aagaacactc ctagatttgg gagcaaaagc     2160

aagtctgcca ctaacctagg acgacaaggc aacttttttg cttctccaat gctcaagtga     2220

agtcacatct gcctgttact tcccagcatt gactgactat aagaaaggac acatctgtac     2280

tctgctctgc agcctcctgt actcattact acttttagca ttctccaggc ttttactcaa     2340

gtttaattgt gcatgagggt tttattaaaa ctatatatat ctccccttcc ttctcctcaa     2400

gtcacataat atcagcactt tgtgctggtc attgttggga gcttttagat gagacatctt     2460

tccaggggta gaagggttag tatggaattg gttgtgattc tttttgggga agggggttat     2520

tgttcctttg gcttaaagcc aaatgctgct catagaatga tctttctcta gtttcattta     2580

gaactgattt ccgtgagaca atgacagaaa ccctacctat ctgataagat tagcttgtct     2640

cagggtggga agtgggaggg cagggcaaag aaaggattag accagaggat ttaggatgcc     2700

tccttctaag aaccagaagt tctcattccc cattatgaac tgagctataa tatggagctt     2760

tcataaaaat gggatgcatt gaggacagaa ctagtgatgg gagtatgcgt agctttgatt     2820

tggatgatta ggtctttaat agtgttgagt ggcacaacct tgtaaatgtg aaagtacaac     2880

tcgtatttat ctctgatgtg ctgctggctg aactttgggt tcatttgggg tcaaagccag     2940

tttttctttt aaaattgaat tcattctgat gcttggcccc cataccccca accttgtcca     3000

gtggagccca acttctaaag gtcaatatat catcctttgg catcccaact aacaataaag     3060

agtaggctat aagggaagat tgtcaatatt ttgtggtaag aaaagctaca gtcatttttt     3120

ctttgcactt tggatgctga aatttttccc atggaacata gccacatcta gatagatgtg     3180

agctttttct tctgttaaaa ttattcttaa tgtctgtaaa aacgattttc ttctgtagaa     3240

tgtttgactt cgtattgacc cttatctgta aaacacctat ttgggataat atttggaaaa     3300

aaagtaaata gctttttcaa aatgaa                                          3326


<210>  2413
<211>  893
<212>  DNA
<213>  homo sapiens

<400>  2413
gcgggttcct tatcctccgc cttggcgcct ctccgcccac cgcccaccgc ccctccctgg       60

cattggttgg cgccagggga agccgaggct ccatcctttc tgcgcaggtt cccgccgcac      120

tcgcgcagac ctagcgcgtc caggtgggag gttagtgtgg cccgggcgtc cgctcctcag      180

cggatgtggc agccccgagc catggctctc gccgtccgag tcgtttattg tggcgcttga      240

ggctacaagt ccaagtatct tcagctcaag aagaagttag aagatgagtt ccccggccgc      300

ctggacatct gcggcgaggg aactccccag gccaccgggt tctttgaagt gatggtagcc      360

gggaagttga ttcactctaa gaagaaaggc gatggctacg tggacacaga aagcaagttt      420

ctgaagttgg tggccgccat caaagccgcc ttggctcagg gctaatgcgc cctgaaggca      480

gagtccaggg accttgaccc agcccctctc agcagacgct tcatgatagg aaggactgaa      540

aagtcttgtg gacacctggt ctttccctga tgttctcgtg gctgctgttg ggggcagaga      600

ttgacgcccc cggtctttgc ctctgagcgg gagagtctgt gtgtatgtgt cttccccgga      660

atccacacca ccccaccctc ctcctgtccc gtggtttcat catatctctt tgcatacccc      720

atgtcttccc cagttgtccc ctggagtttg gggggacatc ccgcctcagg catccttctc      780

aaggggaagc caagagaggc atcaggatgg gtgggtttct gattgtggca acgtttgcaa      840

ccgttcacga ttcaataaat attggatgaa tttaaccgaa aaaaaaaaaa aaa             893


<210>  2414
<211>  4811
<212>  DNA
<213>  homo sapiens

<400>  2414
ggtggtgcca aattctgggg cctaggcatt tccctcgctt tatgtttttg gttttttttc       60

ttccttcaat ctctttgatt aggccgtacg tggctgtggc aaggagttgg ggaaaaaaat      120

tataaaaaca ggaaagagag aaagcacagc cagagccccg gcttcgcgag ccgccgggga      180

gggggcggag gaggctgagc caggcagagt cgccagcgga gactcgcgag tggcgcgcgg      240

gaggagcggc cgccggcgct gggcttgcct tgctgctgct gctgctgctg cctccccacc      300

gccttttttt ttttttaatc tggagcgggg tggggagtgg gaaccggaga gaaagcaaaa      360

tattaaaaag ccccaaagac agccagcagg agcgcggtgc ccgatggctt cgctgtacca      420

gaggttcact ggcaagatca acacctcgag gtccttcccc gcgcccccgg aggcgagtca      480

cctcctgggc ggccaggggc ccgaggagga cggcggcgca ggagccaagc ccctcggccc      540

gcgggcgcag gcggcggcgc cccgggagcg cggcggcggc ggcggcggcg cgggtggccg      600

gccccggttc cagtaccagg cgcggagcga tggtgacgag gaggacgagc tggtggggag      660

taaccctccg cagaggaatt ggaaaggaat agcaattgca ctgcttgtca ttctggtcat      720

ctgctccttg atcgtcacct cggtcatact tctgacacca gcggaagata atagtctgtc      780

tcaaaagaag aaggtcactg tagaagatct cttcagtgaa gacttcaaaa ttcatgaccc      840

cgaggctaag tggataagtg atacagaatt catctacaga gaacagaaag gaacagtgag      900

actgtggaat gttgaaacaa atacttctac tgtcttaata gaaggcaaaa aaattgaatc      960

attaagagcc atcagatatg aaatatctcc agatagagag tatgcacttt tttcatacaa     1020

tgtggaaccc atatatcaac actcgtatac tggatattac gtcctgagca aaattcctca     1080

tggggatcct caaagtctgg acccaccaga agtcagcaat gcaaaacttc agtatgcagg     1140

atggggccct aaaggccaac agctgatatt tatttttgaa aacaatatct actactgtgc     1200

acatgtcggg aaacaggcca tccgtgtggt ctccactggc aaggaaggtg tgatttacaa     1260

tggcctcagt gactggctgt atgaagagga gattttgaag acacacatcg cacactggtg     1320

gtctccggat ggcacgagac tcgcctacgc cgccatcaat gattcccgtg tccccatcat     1380

ggagctccca acttacaccg gctccatcta ccccaccgtg aagccctacc actatcccaa     1440

ggctggaagt gagaacccca gcatttccct acacgttatt ggcttaaatg gacccaccca     1500

tgatctggag atgatgccgc ctgatgatcc acggatgagg gagtactaca tcaccatggt     1560

gaagtgggcc accagcacca aggtcgccgt gacctggctg aaccgggcgc agaacgtgtc     1620

catcctcacc ctctgcgacg ccaccacggg ggtctgcacg aagaaacacg aggatgaaag     1680

tgaggcctgg ctccacagac agaatgaaga acctgtgttc tccaaggatg gccgaaagtt     1740

tttcttcatc agagccatcc cccagggagg acgagggaaa ttctatcaca tcacggtgtc     1800

ctcgtcccag cccaacagca gcaacgacaa catccagtcc atcacctccg gggactggga     1860

cgtgaccaag atcctagcct acgatgagaa ggggaataag atctacttcc tgagcacgga     1920

ggacctgcct cggagacgac aactctacag tgccaacacg gtgggcaact tcaacaggca     1980

gtgcctctcc tgtgacctgg ttgagaactg cacctacttc agcgcttcct tcagccatag     2040

catggacttc ttcctgctca agtgcgaagg tcctggtgtt cctatggtga cggtgcacaa     2100

cacaacagat aagaaaaaaa tgtttgacct agaaacaaat gaacatgtca agaaggccat     2160

aaatgaccga cagatgccta aagtggaata cagggacatt gagattgatg attacaacct     2220

gcccatgcag atactgaagc cagcaacctt caccgacacc acccactacc ctctgctcct     2280

ggtggtggat ggcaccccag gcagccagag tgtggctgag aagttcgagg tgagctggga     2340

gacggtgatg gtgagcagcc acggcgcggt ggtggtaaag tgtgacggcc gtggcagcgg     2400

cttccaaggg accaagctcc tgcacgaagt gaggcggcgg ctgggcttgc tggaggagaa     2460

ggaccagatg gaggccgtgc ggacgatgct gaaggagcag tacattgaca ggacgcgcgt     2520

ggccgtgttt gggaaggatt acggtggcta cctgagcacc tacatcctcc cagcaaaggg     2580

agaaaatcaa ggccagacat tcacctgcgg ctctgctctc tctccaataa cagacttcaa     2640

actctatgcc tctgcgtttt ccgagaggta cttgggcctc catggacttg acaacagagc     2700

atacgagatg accaaggtag cccatcgagt ctccgcgctg gaagaacagc agttcctgat     2760

cattcatccc actgccgatg aaaaaattca tttccagcac acagcagaac tcattacaca     2820

actaattagg ggaaaggcta attacagctt acagatttac ccggacgaaa gccattactt     2880

taccagctcc agcctcaaac agcatctgta ccggtccatc atcaacttct tcgtggaatg     2940

cttcaggatc caggacaaac tgctgacagt cacagcgaaa gaggacgagg aggaggacta     3000

agctcaggtc gctctaagca caaacgtggc tctttctaca accagatgca accgagggat     3060

ttccctgccc tccctcttcc ctcggagggg cggggcgggg cggggccggg tgttccatag     3120

catgtgtgtc tcggatgcgg aaggcagttt tgcttgggaa acaagctcct tccccggggt     3180

catcactcac ggcctccatg gcaccaggga caacgctgtc cccgcagcag cgcctcctcc     3240

cggcgcccga gagaccggca cgccacggcc cctcccccaa ggaacagagc aaaggatggt     3300

ggccgcaggc cccacgcgag cccacaggac accggcccct agattccagc caccaagcgg     3360

aagcatgaga cccgcccaca ctagcctctg tgttcccgtt agggacatca caccctgtct     3420

cacgtcgcag tgccatggac gcagcagtta cagcaccatt gttttagcag tgcgtgttca     3480

tatatgggct tgctacttcc tgtaatgagg acgttcaaca tggtgagggg ctacaagaaa     3540

acgcttttct gtacagagtc ttactgtagc tacgctaatg gttaacctga tagaattaac     3600

tcgtattttt ctatggtttt aacctgatgc tccactgtct ccgtcatggg gttgttttgc     3660

tgtttggggt tgggccttgt ttccctttcc tttctccagt ccacgtgtag actttgcgct     3720

tgatgaagaa gcagatcgga agtaactgct ccctcctcaa ggttgtcttc agacgtcttg     3780

gggacgttcc taaacactga gggggaagac agccaatagc acccattaaa agaaatacct     3840

aaataaaacc tctctcccac tcagctatgc tagggcttgg ctgtaggtgt gcactgtcta     3900

tttacatccg tccttacaac catccttgtc ctccttggta ccgtatcaag ctctttccca     3960

tgacatttgg tttaaaaaaa aaaaaaaaaa aaaaaaaaaa acagaaaaaa gacaaagcgt     4020

caactccacc cacaggcccg ctgtgtgtgc tcgggccacg ggagtcctga gggttctgtg     4080

ggcctgcgcg catccctctc ccatcgtggg ggtggctccg tgaccttcct gccacgagca     4140

ggaggttgat gatgtgctac gttagccttg taagatacac ccccaccaaa tgtgcagccg     4200

gtgttcccag tgtatatttc attctcttgt atataaagga agcaatgtgt gtcaggcctc     4260

tgtgcagtca acccagcctc ctcccgccag tgctaacccc gtgttgagcc tgcatgctga     4320

cactgtggcc gatctggact ctagaagtgc tagtttgaaa tatatccatt actgtcattt     4380

ccttttgagc ttgtggacaa gctgaatgtc aggactgact tcgccagctc ccagccctgc     4440

gggggtgtcc ttggcatccc atcagcagag gagatgcgtc cctgttgcat tttggcgttt     4500

ggggctttgg gtttatccac atgagctctg aacgtccgtt atagttaggg tgattggaag     4560

gtctccatca ctgggtgttt taaaggtgat tcaccaccat ttgtgaaagg accaacgtgc     4620

tgataaacag gaccgatccg agtgctacat gactgtgcgt ttgctatttc aatgggcctg     4680

aacgactaca aagccagcta ggtctggaag gggaagccag ctctggccac gacatctggt     4740

cggagggaag tggggatgtg gcatggtagc gtctgttcat ccatggaata aaacattatt     4800

ttaccactcg g                                                          4811


<210>  2415
<211>  4482
<212>  DNA
<213>  homo sapiens

<400>  2415
gcactccagc cctgcagcct ccggagtcag tgccgcgcgc ccgccgcccc gcgccttcct       60

gctcgccgca cctccgggag ccggggcgca cccagcccgc agcgccgcct ccccgcccgc      120

gccgcctccg accgcaggcc gagggccgcc actggccggg gggaccgggc agcagcttgc      180

ggccgcggag ccgggcaacg ctggggactg cgccttttgt ccccggaggt ccctggaagt      240

ttgcggcagg acgcgcgcgg ggaggcggcg gaggcagccc cgacgtcgcg gagaacaggg      300

cgcagagccg gcatgggcat cgggcgcagc gaggggggcc gccgcggggc agccctgggc      360

gtgctgctgg cgctgggcgc ggcgcttctg gccgtgggct cggccagcga gtacgactac      420

gtgagcttcc agtcggacat cggcccgtac cagagcgggc gcttctacac caagccacct      480

cagtgcgtgg acatccccgc ggacctgcgg ctgtgccaca acgtgggcta caagaagatg      540

gtgctgccca acctgctgga gcacgagacc atggcggagg tgaagcagca ggccagcagc      600

tgggtgcccc tgctcaacaa gaactgccac gccggcaccc aggtcttcct ctgctcgctc      660

ttcgcgcccg tctgcctgga ccggcccatc tacccgtgtc gctggctctg cgaggccgtg      720

cgcgactcgt gcgagccggt catgcagttc ttcggcttct actggcccga gatgcttaag      780

tgtgacaagt tccccgaggg ggacgtctgc atcgccatga cgccgcccaa tgccaccgaa      840

gcctccaagc cccaaggcac aacggtgtgt cctccctgtg acaacgagtt gaaatctgag      900

gccatcattg aacatctctg tgccagcgag tttgcactga ggatgaaaat aaaagaagtg      960

aaaaaagaaa atggcgacaa gaagattgtc cccaagaaga agaagcccct gaagttgggg     1020

cccatcaaga agaaggacct gaagaagctt gtgctgtacc tgaagaatgg ggctgactgt     1080

ccctgccacc agctggacaa cctcagccac cacttcctca tcatgggccg caaggtgaag     1140

agccagtact tgctgacggc catccacaag tgggacaaga aaaacaagga gttcaaaaac     1200

ttcatgaaga aaatgaaaaa ccatgagtgc cccacctttc agtccgtgtt taagtgattc     1260

tcccgggggc agggtgggga gggagcctcg ggtggggtgg gagcgggggg gacagtgccc     1320

cgggaacccg gtgggtcaca cacacgcact gcgcctgtca gtagtggaca ttgtaatcca     1380

gtcggcttgt tcttgcagca ttcccgctcc cttccctcca tagccacgct ccaaacccca     1440

gggtagccat ggccgggtaa agcaagggcc atttagatta ggaaggtttt taagatccgc     1500

aatgtggagc agcagccact gcacaggagg aggtgacaaa ccatttccaa cagcaacaca     1560

gccactaaaa cacaaaaagg gggattgggc ggaaagtgag agccagcagc aaaaactaca     1620

ttttgcaact tgttggtgtg gatctattgg ctgatctatg cctttcaact agaaaattct     1680

aatgattggc aagtcacgtt gttttcaggt ccagagtagt ttctttctgt ctgctttaaa     1740

tggaaacaga ctcataccac acttacaatt aaggtcaagc ccagaaagtg ataagtgcag     1800

ggaggaaaag tgcaagtcca ttatgtaata gtgacagcaa agggaccagg ggagaggcat     1860

tgccttctct gcccacagtc tttccgtgtg attgtctttg aatctgaatc agccagtctc     1920

agatgcccca aagtttcggt tcctatgagc ccggggcatg atctgatccc caagacatgt     1980

ggaggggcag cctgtgcctg cctttgtgtc agaaaaagga aaccacagtg agcctgagag     2040

agacggcgat tttcgggctg agaaggcagt agttttcaaa acacatagtt aaaaaagaaa     2100

caaatgaaaa aaattttaga acagtccagc aaattgctag tcagggtgaa ttgtgaaatt     2160

gggtgaagag cttaggattc taatctcatg ttttttcctt ttcacatttt taaaagaaca     2220

atgacaaaca cccacttatt tttcaaggtt ttaaaacagt ctacattgag catttgaaag     2280

gtgtgctaga acaaggtctc ctgatccgtc cgaggctgct tcccagagga gcagctctcc     2340

ccaggcattt gccaagggag gcggatttcc ctggtagtgt agctgtgtgg ctttccttcc     2400

tgaagagtcc gtggttgccc tagaacctaa caccccctag caaaactcac agagctttcc     2460

gtttttttct ttcctgtaaa gaaacatttc ctttgaactt gattgcctat ggatcaaaga     2520

aattcagaac agcctgcctg tccccccgca ctttttacat atatttgttt catttctgca     2580

gatggaaagt tgacatgggt ggggtgtccc catccagcga gagagtttca aaagcaaaac     2640

atctctgcag tttttcccaa gtaccctgag atacttccca aagcccttat gtttaatcag     2700

cgatgtatat aagccagttc acttagacaa ctttaccctt cttgtccaat gtacaggaag     2760

tagttctaaa aaaaatgcat attaatttct tcccccaaag ccggattctt aattctctgc     2820

aacactttga ggacatttat gattgtccct ctgggccaat gcttataccc agtgaggatg     2880

ctgcagtgag gctgtaaagt ggccccctgc ggccctagcc tgacccggag gaaaggatgg     2940

tagattctgt taactcttga agactccagt atgaaaatca gcatgcccgc ctagttacct     3000

accggagagt tatcctgata aattaacctc tcacagttag tgatcctgtc cttttaacac     3060

cttttttgtg gggttctctc tgacctttca tcgtaaagtg ctggggacct taagtgattt     3120

gcctgtaatt ttggatgatt aaaaaatgtg tatatatatt agctaattag aaatattcta     3180

cttctctgtt gtcaaactga aattcagagc aagttcctga gtgcgtggat ctgggtctta     3240

gttctggttg attcactcaa gagttcagtg ctcatacgta tctgctcatt ttgacaaagt     3300

gcctcatgca accgggccct ctctctgcgg cagagtcctt agtggagggg tttacctgga     3360

acattagtag ttaccacaga atacggaaga gcaggtgact gtgctgtgca gctctctaaa     3420

tgggaattct caggtaggaa gcaacagctt cagaaagagc tcaaaataaa ttggaaatgt     3480

gaatcgcagc tgtgggtttt accaccgtct gtctcagagt cccaggacct tgagtgtcat     3540

tagttacttt attgaaggtt ttagacccat agcagctttg tctctgtcac atcagcaatt     3600

tcagaaccaa aagggaggct ctctgtaggc acagagctgc actatcacga gcctttgttt     3660

ttctccacaa agtatctaac aaaaccaatg tgcagactga ttggcctggt cattggtctc     3720

cgagagagga ggtttgcctg tgatttccta attatcgcta gggccaaggt gggatttgta     3780

aagctttaca ataatcattc tggatagagt cctgggaggt ccttggcaga actcagttaa     3840

atctttgaag aatatttgta gttatcttag aagatagcat gggaggtgag gattccaaaa     3900

acattttatt tttaaaatat cctgtgtaac acttggctct tggtacctgt gggttagcat     3960

caagttctcc ccagggtaga attcaatcag agctccagtt tgcatttgga tgtgtaaatt     4020

acagtaatcc catttcccaa acctaaaatc tgtttttctc atcagactct gagtaactgg     4080

ttgctgtgtc ataacttcat agatgcagga ggctcaggtg atctgtttga ggagagcacc     4140

ctaggcagcc tgcagggaat aacatactgg ccgttctgac ctgttgccag cagatacaca     4200

ggacatggat gaaattcccg tttcctctag tttcttcctg tagtactcct cttttagatc     4260

ctaagtctct tacaaaagct ttgaatactg tgaaaatgtt ttacattcca tttcatttgt     4320

gttgtttttt taactgcatt ttaccagatg ttttgatgtt atcgcttatg ttaatagtaa     4380

ttcccgtacg tgttcatttt attttcatgc tttttcagcc atgtatcaat attcacttga     4440

ctaaaatcac tcaattaatc aatgataaaa aaaaaaaaaa aa                        4482


<210>  2416
<211>  5250
<212>  DNA
<213>  homo sapiens

<400>  2416
taatcgttcc tgaaaaaaac aaacaaacaa aaaaaatcac cattcctttt aatagcttga       60

gcctgtacca gaatgataag tggaaattag tcctcaaagt aacctcagct gtttcattat      120

tgtgtgcctc gagcatctgg ttattcaagc tcctcccacg gttcgtattg tgcactcagg      180

cttggcctgt aacattgaag aggagcgcta ctccgaaagg gtctacacta tccgggaagg      240

agaaaccctt gagttgactt gtctagtcac aggacatcca cgtccacagg tggaccaaaa      300

cagcaggaag tgcctctgac agattccaag actcaagtgt cttcaatgag actttgagga      360

ttacaaatat tcagcgacac caaggaggcc ggtattactg taaagcagag aatggcttgg      420

ggtctccagc gataaagtca atcagagtgg atgtatacta tttggatgat ccagtagtaa      480

ctgttcatca aagtataggt gaagctaaag aacaatttta ctatgagaga acagtgttcc      540

tccggtgtgt tgccaattcc aatcctcctg ttcggtatag ctggagacgt ggccaggagg      600

tcttgctgca aggatctgat aaaggagttg agatttatga accattcttt acccagggtg      660

aaacaaagat cttaaaacta aagaatcttc gacctcagga ctatgctaat tatagctgca      720

ttgcttcagt gaggaatgta tgtaatattc ctgataagat ggtgtcgttt agactgtcca      780

ataaaacagc atcaccgtca attaaactct tggtggatga tcctatagtt gtaaatcctg      840

gagaggccat aacattagta tgtgttacaa caggaggaga gcctgcacct tctctcacct      900

gggtcaggtc ctttgggact ctgcctgaaa agactgtttt gaatggagga actttgacca      960

tacctgccat cacctcagat gatgctggta cttacagctg cattgccaat aataatgtgg     1020

gaaaccctgc aaaaaagtcc accaacatca ttgtgagagc attaaaaaaa ggacgatttt     1080

ggatcacacc agatccttat cacaaagatg acaacatcca gattggccgt gaggtgaaaa     1140

tatcttgcca agtagaagct gttccttctg aggagctaac atttagttgg tttaaaaatg     1200

gtcgtccatt aagaagttct gagcggatgg tcattacaca gactgatcct gatgtctctc     1260

cgggaacaac aaacttggac atcattgatt taaaattcac ggattttggg acgtacacat     1320

gtgtagcatc tctgaaggga ggaggaatat ctgatatcag tatcgatgtt aatatatcca     1380

gcagcacagt tccacccaat ctgactgttc cacaggaaaa atcaccattg gtcaccagag     1440

aaggagacac aatagaactg caatgtcaag taactggcaa acctaaacca atcatccttt     1500

ggtctagagc ggataaagaa gttgcaatgc ctgatggatc aatgcaaatg gagagttatg     1560

atggaacact gaggattgtg aatgtatcta gggaaatgtc aggaatgtac agatgtcaga     1620

ccagccaata caatggattt aacgtgaaac caagggaagc cttggtgcag ctcatcgttc     1680

agtatccccc tgcagtggaa ccagcattct tggaaatccg gcaaggacag gatcgaagtg     1740

tcactatgag ttgcagagta ctgagagcct atccaatacg ggtgctgacc tatgagtggc     1800

gcttgggcaa taaattatta cggacgggtc aatttgactc tcaggaatac acagagtacg     1860

ctgtgaagag tctttccaat gaaaactatg gggtttataa ctgtagcatc ataaatgaag     1920

ctggagctgg gagatgcagc tttcttgtta caggaaaggc ctatgctcca gaattctatt     1980

atgataccta caatccagta tggcagaaca gacaccgtgt ttattcttac agtctacagt     2040

ggacacagat gaatcctgat gcagtggatc ggattgttgc ataccggttg ggcatcaggc     2100

aggctggaca gcagcgctgg tgggagcagg agattaaaat aaatgggaat attcaaaagg     2160

gagaattaat tacatataac ttgacagagc taattaaacc agaagcttat gaagtccgac     2220

tgactcctct caccaaattt ggtgaaggag attcaacaat tcgtgtgatc aaatatagtg     2280

ctcctgtaaa tcctcatttg agagaatttc attgtggatt tgaagatggt aatatttgtt     2340

tgttcactca agatgataca gataattttg actggacaaa gcaaagtaca gcaacaagaa     2400

atacaaaata tactcctaat acaggaccta atgctgaccg tagtggctcc aaagaaggtt     2460

tttatatgta cattgagaca tcacgaccca gattggaagg cgaaaaggct cgacttctca     2520

gccctgtttt cagcatagct cccaaaaacc cttatggacc cacaaacact gcatattgtt     2580

tcagcttctt ttatcacatg tatggacaac atataggtgt cttaaatgtt tatctacgtt     2640

tgaaagggca aacaacaata gagaatccac tgtggtcttc aagtgggaat aaaggacaaa     2700

gatggaatga ggctcatgtt aatatatacc caattacttc atttcagctc atttttgaag     2760

gtatccgagg tcctggaata gaaggtgaca ttgctattga tgatgtatca attgcagaag     2820

gagaatgtgc aaaacaagac ctagcaacta agaattccgt tgatggtgct gttgggattt     2880

tggttcatat atggcttttt cccattatcg tcctcatctc tatcttaagt cctcgaaggt     2940

gaccttatcc tggcagaggc tataaaagat tcaccaggca ctggcatgaa gaaagagtct     3000

ttgtaaatgg acattgaaca aacaaactac caaagattcc tccactgact actgactcaa     3060

aaataaaata ataaaaacaa atttttttaa gcactgggga taaaaagaca tcatggaagt     3120

ataacttatt ccagactaaa cataaaagat aatcttgacc tgagtagaga agagaccttc     3180

aggtgctttt gtggctaaaa agattacagc gtcatctggt tgaactctgg aaaaaaaaaa     3240

aaaaatgaaa aaaagaaaaa aaaaagagct atagaaatcc ttgtcaaagc acaaagtcat     3300

ggctggtttt gtttcaaatg aatagtttgc ttgttaccat ggaaacctaa tggcctgcca     3360

acaaaaacct cactgtaaac agggtacgtg aagagctggc atttattttc cttacgagaa     3420

ggttttcgta gagaattaaa taaatgtagg cccttttacc tttggctgtt acccttcctt     3480

gaaaataacc cgaactcaga attatttaaa gcattcatgt ttctccccac cttatcccca     3540

tcccaccttt attattatta tttttctccc atggctaagc tagataactg tatgctgtct     3600

ctttttgcat gcactactat ccaggatggt aaacctgggc ttacatgtta cacaggctta     3660

tcggagtttg cttgcggcca cttgaacacc caaactacgt catctgttcc aatgaagaaa     3720

ccaaaccacc atcttttata aattgccatg gaaaccaagt gccttcaatg aaacaagcct     3780

gaataatttt caactcagaa gcttgcactg ctaagagtgg tttgtgtaaa actattttat     3840

aaacaaacta cagagcctaa atgtgcaaat tacaggcaag acaacaaagc cgcttctgaa     3900

gaagaaagga ccgaagctgc tgcgtaagcc catgcagaca agatatttgt tgtttaacct     3960

cctagacagc catggccttt cggcttattg tccattagaa aatcacttcc attgagacca     4020

gacatggagc aacacttttt ttcttccagg ttattaaatg ggtcaaccag agcaaaaggt     4080

tattaagaat acttagtgca gaaggtggta aaacacaaaa gtgatttttt tactctaacc     4140

tccatttgaa atgaaattgg ccctagcttt agagggaaca agaaaatgtt tgggattgca     4200

gtgcatacta actctacagt ggaactgggc ctgaaaaatc tggctttatt ctaaactctg     4260

agggtaatat gcctctgccc tttagtcaga ctctgtgcaa attgtgaaat attattttat     4320

tattttacca agattataaa aacactttta caaaaaaaca aaaacctgta aaaataattt     4380

tgagctacct gacgacaaat catatcttta accagccagt tttccaatgc attgtaaatt     4440

tcacttaaac ctgttggtta tgaaaatttg aagatcattt tccttaaatt atctcagctt     4500

ttaacttcat ttaaaaagac ttttgtctaa gaagaatatt attattatat gttctttcaa     4560

caccccagga ttaaaaaaac tgattatgca agcaattgga atataagtat taaattatag     4620

catttgcaaa tattaatata aaagcacaac aaaatgtagt ggaaaatgac aaagcttgtt     4680

ttttaaaaca attctgtaga aatgtttgtg caaattcagt aattcaactt aaaatataat     4740

tttacagcta tgttcaataa agcctctttc caggtaaggt atgacaagca gtatgtgtgt     4800

ttgttgagca atgttcactt atcactaaaa tgaaattagt tatacaattt attggttacc     4860

atgggataaa tcttcagtgc tccacatacc ttaatgtctg cagaaagaaa ttttaatagg     4920

aactccctga tgcactcccc tatattgtaa tacatgcaga aagcagttaa acctttgaag     4980

gtaaaatatg aaacatatat gaacctggaa tttaatgtct attttcagtc agttcaaaag     5040

gggaccagtt tgaatattta ggtagtgatg gaattgatct gaaccaagtc ctttaaatta     5100

aacataataa acaaatgagt ttcataactt atttgaatga attagacatc ttaaaatttt     5160

ttcagagttt cacagtaacc catatacttt atcagaccaa agagattcaa gtacacaata     5220

tctggggcat ttcttttacg ttttacaaaa                                      5250


<210>  2417
<211>  1054
<212>  DNA
<213>  homo sapiens

<400>  2417
gcccccgcct ggagtccaga cccgacggcc ggcccagttc cacgcaccca gcgagcccaa       60

gcgccttctc cgcaccaggg aagccccacc caccagaagc caagatgtcc agcaagcggg      120

ccaaagccaa gaccaccaag aagcggccac agcgggccac atccaatgtc ttcgcaatgt      180

ttgaccagtc ccagatccag gagtttaagg aggctttcaa catgattgac cagaaccgtg      240

atggcttcat tgacaaggag gacctgcacg acatgctggc ctcgctgggt ttcatccatg      300

aggaccacct ccgggagctg ctcaccacca tgggtgaccg cttcacagat gaggaagtgg      360

acgagatgta ccgggaggca cccattgata agaaaggcaa cttcaactac gtggagttca      420

cccgcatcct caaacatggc gccaaggata aagacgacta ggccacccca gccccctgac      480

accccagccc ccgccagtca cccctccccg cacacacccg tccataccag ctccctgccc      540

atgaccctcg ctcagggatc cccctttgag gggttagggt cccagttccc agtggaagaa      600

acaggccagg agaagtgcgt gccgagctga ggcagatgtt cccacagtga ccccagagcc      660

ctgggctata gtctctgacc cctccaagga aagaccacct tctggggaca tgggctggag      720

ggcaggacct agaggcacca agggaaggcc ccattccggg gctgttcccc gaggaggaag      780

ggaaggggct ctgtgtgccc cccaggagga agaggccctg agtcctggga tcagacaccc      840

cttcacgtgt atccccacac aaatgcaagc tcaccaaggt cccctctcag tccccttccc      900

tacaccctga ccggccactg ccgcacaccc acccagagca cgccacccgc catgggagtg      960

tgctcaggag tcgcgggcag cgtggacatc tgtcccagag ggggcagaat ctccaataga     1020

ggactgagca ctgctaaaaa aaaaaaaaaa aaaa                                 1054


<210>  2418
<211>  2450
<212>  DNA
<213>  homo sapiens

<400>  2418
cgggtcggtg acgtcaccgc atgactgggt ttttatgaat gaaaggaatc ctgtgagtga       60

gtaattccgg gaagctcgcc ttacaactcc gcgcggcctc ggccccctgc gccgcccgcc      120

ccacaacaaa actcagcgca gcgctcccgg gcgcccggtt cagagcgacc tgcggctcag      180

agcggagggg agactgaccg gagcgcggat cgggacagcg gccgggacag cggcgagacg      240

cgcgtgtgtg agcgcgccgg accaagcggg cccagaagcg ggtctgcagc ccagagggca      300

ccttctgcaa acatgtctgt ggatccccta tccagcaaag ctctaaagat caagcgagag      360

ctgagcgaga acacgccgca cctgtcggac gaggcgctga tggggctgtc ggtgcgcgag      420

ctgaaccggc atctgcgcgg gctctccgcc gaggaggtga cacggctcaa gcagcggcgc      480

cgcacactca aaaaccgtgg ctacgccgcc agctgccgcg tgaagcgcgt gtgccagaag      540

gaggagctgc agaagcagaa gtcggagctg gagcgcgagg tggacaagct ggcgcgcgag      600

aacgccgcca tgcgcctgga gctcgacgcg ctgcgcggca agtgcgaggc gctgcagggc      660

ttcgcgcgct ccgtggccgc cgcccgcggg cccgccacgc tcgtggcgcc ggccagcgtc      720

atcaccatcg tcaagtccac cccgggctcg gggtctggcc ccgcccacgg cccggacccc      780

gcccacggcc cggcctcctg ctcctagtgc ccgcccccgc catgcctcag ccacgcccct      840

ccggcctcag ctccctcccc aaagtgcctg agcgccgcct ctgtgcccag gtcccatttc      900

tctgcagcac tggccccttg gtgcacacac attcccttcg tgggccctgt cttcctcttg      960

cagcccccca aactgggacc gaatgaccct gggaagggga acttgggtag gttggggatg     1020

gggcagaggt ctggatctgg gatcgccctt ggctgaaagt ttagcctttt tagattgaga     1080

gatacagagc cggcttagag aacagctgtt gggggagaag agggcacccc tcatcttgga     1140

aactgctctt attgtgccaa tatgccctcc aaaccctccc aggattcaaa gctaggtttg     1200

gctgtctgtg acttacggga ccgtcctgct gagaaattgc actgaagaga tgcccccacc     1260

tctggttggg cctgggggtg cctggccttc cgaaactaaa agagtgggtg ggaagactag     1320

tgaaacccag ttcacggatg gggaaacagg cctgaggtca catttcactt agtggttgtg     1380

ttgggaccaa aacctgggtg tcctcactgc tgccctgagt ccagccatgg ttttcagggg     1440

gacagtggac agggactcag aaatgtggtg ggagggcctc cctggcttgg gagaccgctc     1500

tctgcaaggg agggggagag aagcagaggg agagagaagg tgacacggat ggaagagtgg     1560

gaaggagctg gcctggctca gccctaggct gtccctgcag ccagggtgtc cgggggctgg     1620

ccagtcagag aaagggggcc atggactgct gtggcaaata gggagacaag gagacagacc     1680

ctgcagtcct actacagtct ggagtggggt cctaagaaga agggtcccac ctcaacccct     1740

gtcagtgtcc actgtggggt gggggctgac ccctgccttt gattgtcatt ctcctgggaa     1800

gcccagtctc agtccctccc ccaacactgt ccacactgcc cctccccact gtttatttat     1860

tgcacggatc taagttattc tccccagcca gagcccgagc tcctgctccc tgggaaaagt     1920

ggcgtatggc cctgagctgg gctttatatt ttatatctgc aaataaatca cattttatct     1980

tatatttagg gaaagccgga gagcaacaac aaaaaatgtt taagccgggc gcggtggctc     2040

acatctgtaa tcccagcact ttgggagtcc aaggaggggg atcgcttgag tccaggagtt     2100

tgagaccagc ctggacaaca tggtgaaacc ccatctctac aaaaaataca aaaattagcc     2160

atgcatggtg gctcatgcct gtagtcccag ctacttggga ggctgaggca ggaggatcac     2220

ttaagcccag aaggcagagg ttgtagtgag ctgagatcgc accactgcac tccagcctgg     2280

gcaacatagc aaaatcctgt ctcaaaaaaa aagttaaaaa atattgcccg gctcctagaa     2340

tttatttatt tcctgactta cagcaagcga gttatcgtct tctgtatttt gtagactttc     2400

taaataaagt caaattcttt ctttttccac agagaataaa aaaaaaaaaa                2450


<210>  2419
<211>  2476
<212>  DNA
<213>  homo sapiens

<400>  2419
cgggtcggtg acgtcaccgc atgactgggt ttttatgaat gaaaggaatc ctgtgagtga       60

gtaattccgg gaagctcgcc ttacaactcc gcgcggcctc ggccccctgc gccgcccgcc      120

ccacaacaaa actcagcgca gcgctcccgg gcgcccggtt cagagcgacc tgcggctcag      180

agcggagggg agactgaccg gagcgcggat cgggacagcg gccgggacag cggcgagacg      240

cgcgtgtgtg agcgcgccgg accaagcggg cccagaagcg ggtgaggaac gcgggaccag      300

gaggacggtc tgcagcccag agggcacctt ctgcaaacat gtctgtggat cccctatcca      360

gcaaagctct aaagatcaag cgagagctga gcgagaacac gccgcacctg tcggacgagg      420

cgctgatggg gctgtcggtg cgcgagctga accggcatct gcgcgggctc tccgccgagg      480

aggtgacacg gctcaagcag cggcgccgca cactcaaaaa ccgtggctac gccgccagct      540

gccgcgtgaa gcgcgtgtgc cagaaggagg agctgcagaa gcagaagtcg gagctggagc      600

gcgaggtgga caagctggcg cgcgagaacg ccgccatgcg cctggagctc gacgcgctgc      660

gcggcaagtg cgaggcgctg cagggcttcg cgcgctccgt ggccgccgcc cgcgggcccg      720

ccacgctcgt ggcgccggcc agcgtcatca ccatcgtcaa gtccaccccg ggctcggggt      780

ctggccccgc ccacggcccg gaccccgccc acggcccggc ctcctgctcc tagtgcccgc      840

ccccgccatg cctcagccac gcccctccgg cctcagctcc ctccccaaag tgcctgagcg      900

ccgcctctgt gcccaggtcc catttctctg cagcactggc cccttggtgc acacacattc      960

ccttcgtggg ccctgtcttc ctcttgcagc cccccaaact gggaccgaat gaccctggga     1020

aggggaactt gggtaggttg gggatggggc agaggtctgg atctgggatc gcccttggct     1080

gaaagtttag cctttttaga ttgagagata cagagccggc ttagagaaca gctgttgggg     1140

gagaagaggg cacccctcat cttggaaact gctcttattg tgccaatatg ccctccaaac     1200

cctcccagga ttcaaagcta ggtttggctg tctgtgactt acgggaccgt cctgctgaga     1260

aattgcactg aagagatgcc cccacctctg gttgggcctg ggggtgcctg gccttccgaa     1320

actaaaagag tgggtgggaa gactagtgaa acccagttca cggatgggga aacaggcctg     1380

aggtcacatt tcacttagtg gttgtgttgg gaccaaaacc tgggtgtcct cactgctgcc     1440

ctgagtccag ccatggtttt cagggggaca gtggacaggg actcagaaat gtggtgggag     1500

ggcctccctg gcttgggaga ccgctctctg caagggaggg ggagagaagc agagggagag     1560

agaaggtgac acggatggaa gagtgggaag gagctggcct ggctcagccc taggctgtcc     1620

ctgcagccag ggtgtccggg ggctggccag tcagagaaag ggggccatgg actgctgtgg     1680

caaataggga gacaaggaga cagaccctgc agtcctacta cagtctggag tggggtccta     1740

agaagaaggg tcccacctca acccctgtca gtgtccactg tggggtgggg gctgacccct     1800

gcctttgatt gtcattctcc tgggaagccc agtctcagtc cctcccccaa cactgtccac     1860

actgcccctc cccactgttt atttattgca cggatctaag ttattctccc cagccagagc     1920

ccgagctcct gctccctggg aaaagtggcg tatggccctg agctgggctt tatattttat     1980

atctgcaaat aaatcacatt ttatcttata tttagggaaa gccggagagc aacaacaaaa     2040

aatgtttaag ccgggcgcgg tggctcacat ctgtaatccc agcactttgg gagtccaagg     2100

agggggatcg cttgagtcca ggagtttgag accagcctgg acaacatggt gaaaccccat     2160

ctctacaaaa aatacaaaaa ttagccatgc atggtggctc atgcctgtag tcccagctac     2220

ttgggaggct gaggcaggag gatcacttaa gcccagaagg cagaggttgt agtgagctga     2280

gatcgcacca ctgcactcca gcctgggcaa catagcaaaa tcctgtctca aaaaaaaagt     2340

taaaaaatat tgcccggctc ctagaattta tttatttcct gacttacagc aagcgagtta     2400

tcgtcttctg tattttgtag actttctaaa taaagtcaaa ttctttcttt ttccacagag     2460

aataaaaaaa aaaaaa                                                     2476


<210>  2420
<211>  3008
<212>  DNA
<213>  homo sapiens

<400>  2420
actaggcagg gatgagcaag aggaatggct cacccttgag agctggggtc catagcccag       60

gtcagttctc cagctctccc acttaccagc caagacagga ggtgaggatt gagatgggat      120

gaacccagca ggcggccatg ggttaaaggt cgccatgaat gtaatgtgcc cagcacagtg      180

cctgctaaaa ggcaacactc ccttcctggt ctgaagacca aacaagcaga ctgtactcag      240

gaaagccaga agaaccttcc agctgtctgg accagaaggt gccagcccag gggctgaaga      300

agacgtaatg cccagagcaa aaagcgcctg cagccccctg aagggctggg tgctctggaa      360

tagatgaggg ggcgaaatgg ggctggggac cagggacgga cagggtgggt ccagcacctg      420

cctcgcttcc gaagggctgc tccaacactg aaaaacaccc aaccagcttc ctttcagaaa      480

gactggaata ttccaaaact tctcactgga ggctccggag gaggtgggct ccagctgaaa      540

aggaaatgtg gaggcgtggg cgctcccggc ctgcatcctg cacctcttac actttggttt      600

tcccacagac tcctgaagaa taggtcagaa gaaagggtta aagccttaaa aggggaacaa      660

ccattgcggg gctcagggag gaggataatg ttctttgggc tgccgcaccc tgatccccgg      720

ggtcccgaac cctcccgtcc ctggccaggc ctgccagcca cagggtgagg gcccccttcc      780

gccgcaacct gccactctca caccaatgcg ggaccgcctt ctcttccttc cccacccccc      840

accccaccct gccgtccttt ctcccccaat ctccgcctct gattggctga gcccccggct      900

ccccgctccc cctctcctcc atccccggtg aaaactgcgg gctccgagct gggtgcagca      960

accggaggcg gcggcgcgtc tggaggaggc tgcagcagcg gaagacccca gtccagatcc     1020

aggactgaga tcccagaacc atgaacctgg ccatcagcat cgctctcctg ctaacagtct     1080

tgcaggtctc ccgagggcag aaggtgacca gcctaacggc ctgcctagtg gaccagagcc     1140

ttcgtctgga ctgccgccat gagaatacca gcagttcacc catccagtac gagttcagcc     1200

tgacccgtga gacaaagaag cacgtgctct ttggcactgt gggggtgcct gagcacacat     1260

accgctcccg aaccaacttc accagcaaat acaacatgaa ggtcctctac ttatccgcct     1320

tcactagcaa ggacgagggc acctacacgt gtgcactcca ccactctggc cattccccac     1380

ccatctcctc ccagaacgtc acagtgctca gagacaaact ggtcaagtgt gagggcatca     1440

gcctgctggc tcagaacacc tcgtggctgc tgctgctcct gctctccctc tccctcctcc     1500

aggccacgga tttcatgtcc ctgtgactgg tggggcccat ggaggagaca ggaagcctca     1560

agttccagtg cagagatcct acttctctga gtcagctgac cccctccccc caatccctca     1620

aaccttgagg agaagtgggg accccacccc tcatcaggag ttccagtgct gcatgcgatt     1680

atctacccac gtccacgcgg ccacctcacc ctctccgcac acctctggct gtctttttgt     1740

actttttgtt ccagagctgc ttctgtctgg tttatttagg ttttatcctt ccttttcttt     1800

gagagttcgt gaagagggaa gccaggattg gggacctgat ggagagtgag agcatgtgag     1860

gggtagtggg atggtggggt accagccact ggaggggtca tccttgccca tcgggaccag     1920

aaacctggga gagacttgga tgaggagtgg ttgggctgtg cctgggccta gcacggacat     1980

ggtctgtcct gacagcactc ctcggcaggc atggctggtg cctgaagacc ccagatgtga     2040

gggcaccacc aagaatttgt ggcctacctt gtgagggaga gaactgagca tctccagcat     2100

tctcagccac aaccaaaaaa aaataaaaag ggcagccctc cttaccactg tggaagtccc     2160

tcagaggcct tggggcatga cccagtgaag atgcaggttt gaccaggaaa gcagcgctag     2220

tggagggttg gagaaggagg taaaggatga gggttcatca tccctccctg cctaaggaag     2280

ctaaaagcat ggccctgctg cccctccctg cctccaccca cagtggagag ggctacaaag     2340

gaggacaaga ccctctcagg ctgtcccaag ctcccaagag cttccagagc tctgacccac     2400

agcctccaag tcaggtgggg tggagtccca gagctgcaca gggtttggcc caagtttcta     2460

agggaggcac ttcctcccct cgcccatcag tgccagcccc tgctggctgg tgcctgagcc     2520

cctcagacag ccccctgccc cgcaggcctg ccttctcagg gacttctgcg gggcctgagg     2580

caagccatgg agtgagaccc aggagccgga cacttctcag gaaatggctt ttcccaaccc     2640

ccagccccca cccggtggtt cttcctgttc tgtgactgtg tatagtgcca ccacagctta     2700

tggcatctca ttgaggacaa agaaaactgc acaataaaac caagcctctg gaatctgtcc     2760

tcgtgtccac ctggccttcg ctcctccagc agtgcctgcc tgcccccgct tcgctggggt     2820

ctccacgggt gaggctgggg aacgccacct cttcctcttc cctgacttct ccccaaccac     2880

ttagtagcaa cgctacccca ggggctaatg actgcacact gggcttcttt tcagaatgac     2940

cctaacgaga cacatttgcc caaataaacg aacatcccat gtctgctgac tcaaaaaaaa     3000

aaaaaaaa                                                              3008


<210>  2421
<211>  3008
<212>  DNA
<213>  homo sapiens

<400>  2421
actaggcagg gatgagcaag aggaatggct cacccttgag agctggggtc catagcccag       60

gtcagttctc cagctctccc acttaccagc caagacagga ggtgaggatt gagatgggat      120

gaacccagca ggcggccatg ggttaaaggt cgccatgaat gtaatgtgcc cagcacagtg      180

cctgctaaaa ggcaacactc ccttcctggt ctgaagacca aacaagcaga ctgtactcag      240

gaaagccaga agaaccttcc agctgtctgg accagaaggt gccagcccag gggctgaaga      300

agacgtaatg cccagagcaa aaagcgcctg cagccccctg aagggctggg tgctctggaa      360

tagatgaggg ggcgaaatgg ggctggggac cagggacgga cagggtgggt ccagcacctg      420

cctcgcttcc gaagggctgc tccaacactg aaaaacaccc aaccagcttc ctttcagaaa      480

gactggaata ttccaaaact tctcactgga ggctccggag gaggtgggct ccagctgaaa      540

aggaaatgtg gaggcgtggg cgctcccggc ctgcatcctg cacctcttac actttggttt      600

tcccacagac tcctgaagaa taggtcagaa gaaagggtta aagccttaaa aggggaacaa      660

ccattgcggg gctcagggag gaggataatg ttctttgggc tgccgcaccc tgatccccgg      720

ggtcccgaac cctcccgtcc ctggccaggc ctgccagcca cagggtgagg gcccccttcc      780

gccgcaacct gccactctca caccaatgcg ggaccgcctt ctcttccttc cccacccccc      840

accccaccct gccgtccttt ctcccccaat ctccgcctct gattggctga gcccccggct      900

ccccgctccc cctctcctcc atccccggtg aaaactgcgg gctccgagct gggtgcagca      960

accggaggcg gcggcgcgtc tggaggaggc tgcagcagcg gaagacccca gtccagatcc     1020

aggactgaga tcccagaacc atgaacctgg ccatcagcat cgctctcctg ctaacagtct     1080

tgcaggtctc ccgagggcag aaggtgacca gcctaacggc ctgcctagtg gaccagagcc     1140

ttcgtctgga ctgccgccat gagaatacca gcagttcacc catccagtac gagttcagcc     1200

tgacccgtga gacaaagaag cacgtgctct ttggcactgt gggggtgcct gagcacacat     1260

accgctcccg aaccaacttc accagcaaat acaacatgaa ggtcctctac ttatccgcct     1320

tcactagcaa ggacgagggc acctacacgt gtgcactcca ccactctggc cattccccac     1380

ccatctcctc ccagaacgtc acagtgctca gagacaaact ggtcaagtgt gagggcatca     1440

gcctgctggc tcagaacacc tcgtggctgc tgctgctcct gctctccctc tccctcctcc     1500

aggccacgga tttcatgtcc ctgtgactgg tggggcccat ggaggagaca ggaagcctca     1560

agttccagtg cagagatcct acttctctga gtcagctgac cccctccccc caatccctca     1620

aaccttgagg agaagtgggg accccacccc tcatcaggag ttccagtgct gcatgcgatt     1680

atctacccac gtccacgcgg ccacctcacc ctctccgcac acctctggct gtctttttgt     1740

actttttgtt ccagagctgc ttctgtctgg tttatttagg ttttatcctt ccttttcttt     1800

gagagttcgt gaagagggaa gccaggattg gggacctgat ggagagtgag agcatgtgag     1860

gggtagtggg atggtggggt accagccact ggaggggtca tccttgccca tcgggaccag     1920

aaacctggga gagacttgga tgaggagtgg ttgggctgtg cctgggccta gcacggacat     1980

ggtctgtcct gacagcactc ctcggcaggc atggctggtg cctgaagacc ccagatgtga     2040

gggcaccacc aagaatttgt ggcctacctt gtgagggaga gaactgagca tctccagcat     2100

tctcagccac aaccaaaaaa aaataaaaag ggcagccctc cttaccactg tggaagtccc     2160

tcagaggcct tggggcatga cccagtgaag atgcaggttt gaccaggaaa gcagcgctag     2220

tggagggttg gagaaggagg taaaggatga gggttcatca tccctccctg cctaaggaag     2280

ctaaaagcat ggccctgctg cccctccctg cctccaccca cagtggagag ggctacaaag     2340

gaggacaaga ccctctcagg ctgtcccaag ctcccaagag cttccagagc tctgacccac     2400

agcctccaag tcaggtgggg tggagtccca gagctgcaca gggtttggcc caagtttcta     2460

agggaggcac ttcctcccct cgcccatcag tgccagcccc tgctggctgg tgcctgagcc     2520

cctcagacag ccccctgccc cgcaggcctg ccttctcagg gacttctgcg gggcctgagg     2580

caagccatgg agtgagaccc aggagccgga cacttctcag gaaatggctt ttcccaaccc     2640

ccagccccca cccggtggtt cttcctgttc tgtgactgtg tatagtgcca ccacagctta     2700

tggcatctca ttgaggacaa agaaaactgc acaataaaac caagcctctg gaatctgtcc     2760

tcgtgtccac ctggccttcg ctcctccagc agtgcctgcc tgcccccgct tcgctggggt     2820

ctccacgggt gaggctgggg aacgccacct cttcctcttc cctgacttct ccccaaccac     2880

ttagtagcaa cgctacccca ggggctaatg actgcacact gggcttcttt tcagaatgac     2940

cctaacgaga cacatttgcc caaataaacg aacatcccat gtctgctgac tcaaaaaaaa     3000

aaaaaaaa                                                              3008


<210>  2422
<211>  6149
<212>  DNA
<213>  homo sapiens

<400>  2422
cattttgcta ggcagcggca gtggcggcgg cagcggcggc tggagcctct gattgggttt       60

cggagtccgg tactggagcc aatcagcgcg ggcagcgaac cgggggagcg aggcacggag      120

tgtacctcac agccttctag gatctccaga gtggacagga atctcacttg gagggaccat      180

ggagcagtat acagcaaaca gcaatagttc gacagagcag attgttgtcc aggcaggaca      240

gattcagcag caggtccaag ggcagccatt aatggtgcag gtcagtggag gccagctaat      300

cacatcaact ggccaaccca tcatggtcca ggctgtccct ggtggacaag gtcaaaccat      360

catgcaagta cctgtttctg gaacacaggg tttgcagcaa atacagttgg tcccacctgg      420

acagatccag atccagggtg gacaggctgt gcaggtgcag ggccagcagg gccagaccca      480

gcagatcatc atccagcagc cccagacggc tgtcactgct ggccagactc agacacagca      540

gcagattgct gtccagggac agcaagtggc acagactgct gaagggcaga ccatcgtcta      600

tcaaccagtt aatgcagatg gcaccattct ccagcaagtt acagtccctg tttcaggcat      660

gatcactatc ccagcagcca gtttggcagg agcacagatt gttcaaacag gagccaatac      720

caacacaacc agcagtgggc aagggactgt cactgtgaca ctaccagtgg caggcaatgt      780

ggtcaattca ggagggatgg tcatgatggt tcctggggct ggctctgtgc ctgctatcca      840

aagaatccct ctacctggag cagagatgct tgaagaagag cctctctacg tgaatgccaa      900

acaataccac cgtattctta agaggaggca agcccgagct aaactagagg cagaagggaa      960

aattccaaag gagagaagga aatacctgca tgagtctcgg caccgtcatg ccatggcacg     1020

gaagcgtggt gaaggtggac gatttttctc tccaaaggaa aaggatagtc cccatatgca     1080

ggatccaaac caagccgatg aagaagcaat gacacagatc atccgagtgt cctaacccca     1140

cgccatgtga tggagctgat caaggtcatg tttctcactg ttccaggaaa ttgatcaact     1200

cttccaatgg gacattgatg atcacattct gccctttact acaggacaga aaccacttag     1260

tttttaataa gtggctcagt attacaattg cagcgatgcc tggcaaattg aagttgcaag     1320

cctttgtctt actctttcag tcaggaccta tttcagactg ttgatgacat tgacatttca     1380

tggattcgga tgatgcaagg agacacatgc caccccagca gtacacaaag cacttacctt     1440

gactggtgaa gtcagccagc catctcagca gggaagaaca accttctcaa ccaaaactgc     1500

aatcaggaaa gcagcagccc actccttccc atggaatcta gacagcattt atccctctgg     1560

tgggggaatc tcacactgac taactgaatg gacgctttgt attcagagat ggcttccagg     1620

caaggaagtt ctatcttgtg atacggaaac aataaattcc tgagatacat tcttccaatc     1680

tgtggtaata ataagaattc ctctctgccc agatggtagg ttgatatttc tggactctag     1740

ccaagaaaaa gctaattctg gggatagaat gataaaagac tcaagcacta aaaatataca     1800

ttgccgaatc tctttttcta gctttgaaaa gttgtggcct gcttgtccct ctgttgactg     1860

gtcatctgga ccatcgtact tgctgtggct acttctaaga caatgtagag ggttattaaa     1920

ccttgaaact gcctttccta agtagagaac aagactattc aacaacttct ttgctgaagc     1980

actgaggaga tttgtaatac tcctaaagga agggccaaac tagagatttt caatcataga     2040

ctttgtgaca gcatttgggg aactaaaaga ttcatgtgtt tcagcctagt gggagagagt     2100

gggggagagg aagagagaga gagagcatgt atacccgtat gttatcatag agcacgattc     2160

tccagtggat ggatacctgg aatggatcat taagatgaag agagtaattc acatttactc     2220

tagaaccttt aacaagcact gaaaggaaga agcctgagat ttgatccttg acaatttctg     2280

gaaagcactg gtcagtcaca ctgtcctgga cagagtccaa gttacccact aaagcttgag     2340

gtggatgttg gcttcactcc tgcagcacaa tgctggccct agaaagcgag cattttcatt     2400

cttcccatgg cagctgattc tttggtgcca gttttcatgt tttctccata ggccttgtgc     2460

agaaaggttt tctcattgca tccatactgt gagaataaac tgcagactga aagaaacatg     2520

cctgcagggt caggaactgg gccactgttc ccagaacggg ttgtgcctca gaaatctatt     2580

tctcttttag atgttgaacc ctgagagaac taagatgata tttcagaaga gttggctgcc     2640

ttctctggaa acaaggaaaa cccaataatt ccgaggaaca ttgggggtta aataccaaga     2700

ataaaaattg gttcttcttt gacttcagct taactgtatt aagacagaaa ttaagccctc     2760

taaaaacacc acaaagagag atgattgtaa tgatagaaat agaggtacag agctatgcaa     2820

aggaaacagg aagtgaaata ttcctagtcc cagggatctg gtaatcgctc ctggcttcca     2880

gatgtcaaag gactgatcct ttggtaagct cactagaaac ttctagctct acaagagttt     2940

gggatattaa tgttattcag taagtcccaa gtttttcaga gaatagatta ctaacaatga     3000

ggaatttata ttccttggtt aatttaggag tctaagatgc agagttcaga aagaaattac     3060

tcagacctaa ctttgagtgc ttaagctgcc aacagttaga agatgctatt tatttgtgtc     3120

tgtaagtttg tacatagtaa tgccagcctt gttgctgaat tttttatttg gggggagatg     3180

actttgaatt ttgtttgaaa tgcttcagtt gtcattttgt cattgcattt caaatagctc     3240

atgacccttt tcttgtggtc actttggcac accatagtag cccacaaagt gggggcaggg     3300

tattgacatt tggatttttt ctttgatact agttctttta ttcattttta tttgtgactg     3360

tagtgataac tttacagatg gagaaagagt gaatggatga atgaataatt ggtttaatgc     3420

ctagttatgc aacttgagtg cttttttttt tttttgcagg ataattttaa gtgtatatat     3480

tttaactgca ctggtacatt gaacatgtca gtgtcgatgc cactggacca acagagcatt     3540

ttgtggctat agggtgcctg ataataatgt cttgattttt ctttgggatt caactatatc     3600

gaaggttttt cccccagcag tatgggggcg tacaggtgat cgatcattaa tgtcattgca     3660

attgttattt tttaaaataa atttataaaa ataaccgaaa agtaatgtga cttttgagga     3720

atctgcaact cctgggttct agtttgtgtt tccagtgttg aaattttgat ctcccccgac     3780

aagacttgtc tgcatggacg gtgtctctgt aaacagtatc aaacttgtaa tgtctgagcc     3840

tcttagcttt atctcccctt aatttcttcc cttttggccc ttccaccctg ttgaggagat     3900

tttttctgtc acctgcaggc tgatcataca tttgatgcta ctactgaaag tgtttatcaa     3960

aatgtgatga agtaattcca tgaggaaaat tagccgttat cacaaaaaca gccttaagta     4020

ttgtagaatt tcaggtagtg aagatgtact atttacgttt tgttagattt tgttttggca     4080

gaagaccaaa acaaaagtac ttttctgatt gttaaaaatc cacagcatgc tcaccttgtt     4140

actgttttac cttacggtcg ctgggaatct aagcaacaaa gactagaagc ctccgatatg     4200

ccattatcaa cacacaagag acaaacagcc cgaggaagca ctcaatgatg agagcagtag     4260

acctgccctg gcagatgaga gaggagaaac tctccacaat gaaggaaaag cactgacagt     4320

atttgatagc tttagtcaaa ctgtgcttga gtttggctta gatttatgcc agtggaacct     4380

gtccttacca aattcagaga tgacccaaga ttctactctg tggtatgagg gaaagacctc     4440

tcgatattta tctcacacca acggctttat cgtaggagcg tcttcgcctc ccccgtttcc     4500

agtagaaaag acagctttgc tcctttgaaa gcgcagaccg ccgcacctcc agccccttct     4560

ccccggggaa gtaggccccg ctaagaatgt gggaaggtgg tggggcggcg actgaagtcg     4620

cttccgattg gcgttgtccc aaggaagcct gcgcggattg atcggcggca ggcctccaat     4680

agagcctgct aggcggattg gctgctacgc ggctgggccc tgtttccggt acctaggcgg     4740

gcagccatgg tgaccggcga gcggcatgcg acgccgcctc tgtggcctgt ggaggcccgc     4800

ttggcggcgc tgcttcccga cctactggtc tttcggaagc ctcggggatg ggaacccgag     4860

ctcgccacgg cccagggcgt cctcctaggc gtccatgtga cgggtgaggg cgacggccgg     4920

cacttgcact taagtctcct ggcctgcggg agaggcggcc gttgggtcta agcccctgga     4980

ggcctcgacg gttacaggcc tagcctcccg cgagctaagg cacagtttaa cttcgtgctg     5040

cggcttcctt aggaaacttt gagtatcttc gttttagcgt gggaggacat cttttgggat     5100

gaaccggctc agtccttgag ctcaccccaa agatgatgaa attgaaactc agaggaaagg     5160

atttttacag gaccacgccc cgggctttga acccgttttt cccaaccccg agcattttct     5220

attaagcgtt ctgtttcaat tattttattc gttcagttaa ttcgttcttg gcgtcataag     5280

tatatgcccg ccgttgttct ggccgtagct atctagcagc cactccgcga gtcgttcatt     5340

taacaaatac ttactctgtg tcagggatat gaagatgggt aataccaggt gcctgtcctc     5400

actgtgtgag tggttctcta gccagacatg aggagggatc ctattgtttc ccatagctag     5460

gcagcctaag agagtagggg aaagagctgg ctccagatga aaagggcacc atctccagct     5520

cttggaagca gagagggtgg tcctttggat tcccagtggc agcagcaacc aacctggccc     5580

ttagtagttt ctaagttaca ccatgttaat ggataaagga attactcagc ttgaagggat     5640

ctgtttcctt tacactggcc tgatgtgtgg ggagaaaggg gccaaaaagt ttaggatttg     5700

gagttaacat cgtaatttct gctttgttgg tcagggttta cagcattaat ggacaggttc     5760

accctgacct acaagtcgga acgtgacatg gacaaactgg cccatatctt cagttattac     5820

attagtgaca tcgtggagcg tgagtgatca ttgtagggta acaaggtgtg gtgctgggct     5880

cctgggggtt tataaaagaa gggggccaga agtactttaa aacaggtacc aaagggtcat     5940

tcctttagca tcattcatct ttggtttctt caagttgcca ctgaaaagct agacctttgc     6000

ctattatctg ctaatctacc cagtctcaca ttctattgac tcattgttca aagggggggc     6060

aggaggagct aatttccttt gcacatttgt attttatttc aaaataaagt attctcttct     6120

aacaataacg taaaaaaaaa aaaaaaaaa                                       6149


<210>  2423
<211>  4362
<212>  DNA
<213>  homo sapiens

<400>  2423
gttgcggtgg ccaatagacg cattcggaac atcggcggct gcccgggtga cttggttata       60

tgtcacagaa taacattcga gaatgggaca tggaatgagg cgacggcccc agcaagcccc      120

agcagcccca gccccagccc caggcccagc agcagcagca gcagcccctg ctctcccgcc      180

gcccggagag gctctgcagc catgaagcca accgtcccga ggcaccgccg gtaagcaggg      240

agcctccgcg gagctcccgc cgccgctccc ccttggtgag tcctgccgca gcgagaggca      300

tggagaaggc cgcccccgcg gggcgctgat cccctcgccg cgcccgcgcg cacacgcccc      360

ccgccgccgc cgccgctgcc gccgccgcgc gcccccagta cctcgctccc cgcccaggcc      420

ccaccatgac cggctccgcg gccgacactc accgctgccc ccaccccaaa ggcgccaaag      480

gcacccggtc ccggagcagc cacgcgcggc ccgtgagcct cgccaccagc gggggctcag      540

aggaggagga caaagacggc ggggtgctgt tccacgtcaa caagagcggc ttccccatcg      600

acagccacac ctgggagcgc atgtggatgc acgtggccaa ggtgcaccct aaggggggag      660

aaatggtggg cgccatcagg aacgccgcct tcttggcaaa gccttcaata ccccaggtcc      720

caaactacag gctgtcgatg acgatcccag actggctcca ggcgatccag aattacatga      780

agaccctaca ctacttaacc aatgggcagc cttccattga gcggttcccc atcagcttta      840

aaacctactt ctcaggaaac tactttcacc acgttgtgct ggggatttac tgcaatggcc      900

gctatggctc attgggcatg agccgcaggg ctgagctgat ggacaagcca ttgacttttc      960

ggactctgag tgacctcatc tttgactttg aggactctta caagaaatac ctgcacacag     1020

tcaagaaggt caagattggg ctgtacgtcc cccatgagcc tcatagcttc cagcccattg     1080

agtggaagca gctggtcctc aacgtctcaa agatgctgag ggctgacata aggaaggagc     1140

tggagaaata tgccagggac atgagaatga agatcctgaa acctgcaagt gcccactctc     1200

cgacccaagt gagaagccgg ggaaaatccc tgtcccccag aaggagacag gcaagccccc     1260

cgaggaggct cggccggcga gagaagtcgc ctgcactgcc tgaaaagaag gtggctgatc     1320

tgagcactct gaatgaagtg ggctatcaaa tccgaattta gccaagccat accggccagc     1380

aagagggttt ctgtggtgct tctctctgca ctttacccag catcttcagg aggaactgca     1440

actatttatt aagaacttgt gaattttatt tttaaggatt cacctggaaa tagaatctga     1500

gtgggtggta accattagct ttaaaaaatt cactaaaagg caccatgaaa aggctgaagt     1560

aataagcccc actggggttg gactatgtcc ctcactcaag atcttaagga taaccgtaac     1620

tgaagtttta tatttttcca tttacctact ttcttttact tgctttgaac attatgcctc     1680

accaatagta aatgttcatg aaataatctc ttgaactttt ggtatagtaa ggtaactcta     1740

acagtattac tgtctttttc agcaataaca gaaagcaaaa atgggtgggt tttttttaag     1800

cagttattac ctcagcattt tgacatcaga tatgcaaact taatggcgtt ttgttttttt     1860

atattctatt tgtattcttt ccccagtatt tcccatgggg atctccacaa gtttggagtt     1920

ttttcctggt gcacacacgt gaggagattt aaggtactat atgcaagtgt tttactaaaa     1980

agcactgaaa ttcttctggc aatacaagaa ccattttcag gatcttggag ttacttcctt     2040

cttaatcttt cttaaagcat tcactgatgt ttttgttttt tcaaaatgaa acaaaaatat     2100

cacattgaga agctagtcta tgttctgtca ctaacattta aactttgcag actctaacaa     2160

aaagcacaag aggtcacgta ctattataca aatttagcgg tactggattt acctctgaca     2220

ttaacacact caggcagaga ccaggagtga tcagcaggtc ttcagaacca aaaaaccttt     2280

ctgttcacat ttcatctgat ttttaaactg aggcaggctt tgattcttct gaaggatgcc     2340

aagaatcaaa ctaagggagg actcactgtt aaagatgtgt tctgatgtct tatattaaga     2400

ccaaatgtga catgatgtga ttatcttcca gtactttgct tttaggtacc atttcatgac     2460

attttaggaa tgagtattgg aaaatataaa gaattagaaa agcagcactt tttttttaat     2520

ggaaaagtct tcggtccagt gttacacctt atagtgtaat tcagtcccta agcacagaat     2580

gaatgtctgg cctgcatatg gtagttacag tgtaacctct ggctgcagac cacacaggac     2640

aaccctaaca gcctagtctt gtatggtgta aatatcaaga gtacagcttc aatttcattt     2700

gctttatctt agcaacaatg ccaactcagg agagcagacg gccgatttca gtgaagtctg     2760

gtagtcaaca gatgttattt cagtctcagt gcatctcctc tggctttctt tgactgaagg     2820

tgtttatagg aaggaagtta aaaaaaaaaa aagctcattg agattcttta ccaattcttt     2880

acaagatttc tgggggtgac agggaaagca aaaggacttc aaagcaaaag ggtgcacaag     2940

agcttacttc accctgaaaa tcagtattat taatgaaaag tactgttttc ttaaagaagt     3000

cgaatgtcct ttagatgaac aagaccaagt atacatctcc attagattaa aatgtagcac     3060

agggttaaaa attatcagtt taatctcttt aagaacagta ttatcagagt ttaaaatgag     3120

ttagctctgt ttatctacac acagcaaacc cattcgcagc ctcttggcca catgtattca     3180

gatgtttgaa atagtgaatc atttcatttt cattctaaaa caatactgac ttagccatat     3240

accttctgtt tgtcaatctg aaacttgctt acatctaata agtagacctc ttataacact     3300

gcaaccattc taagagttgg aatttatttt tgccaagtat taagtactgt tacatctaaa     3360

atacagaatg tcaaatggtt gcatagcttg tttcccacaa caaggaggaa aagaacagga     3420

atacaaactc tgtaatatgc tgataaagaa gccttagaac tgccaactgg cttgatggtt     3480

caattagtaa gctaatttct cccacacccg ctccttgatt tttagactaa ttttcccaaa     3540

gcaaggttta gtcacacaaa cttgaaagta catttaaaat gttcttagtt gtcatcctac     3600

ttttattgcc tatggaatat gctaatttct aaaaaaaata cgggagaggc accaaacccc     3660

taaattctag tgcaataatt taaaaaacaa aaaacaaaac aaaacaaaaa acatgttata     3720

tgcacccccc tcccaaagct gattttaaga ctggctagaa ttcaaaatat aaaaaataaa     3780

actatgaagt gatttgaaat cggttttaaa aagttgttag tgcaagagaa attttatgtt     3840

taagccatca tggcaatata tgcaaagttt aaatgaatga cagaaatctt gattttagac     3900

tgtatgttgt gctgttttga gtacacttta tttcggagat atttagtatt ttctatacac     3960

tctgaaatca tgagcatttc actttttcta agtcaattat ttcataagga ttttattaat     4020

agatattggt aaatagaact ttggaaatct taattcagaa ttcttactat acctgagtct     4080

tttgtaagct atagttttat gtacaacctt gtacagtttt tttgacatac aattcagaac     4140

tttgtttatt ctcttggact ttgttctggc caatacattt tttttaaatc tttaagaaga     4200

actgtgattg ttttagtggg tatttttcta attaaatgaa aacttgtata atggtatttt     4260

agagaatgcc agtaagtgca tgtttcaagt taatgttttt ctcatcactt gtatgtttct     4320

aacacagcat gggactttaa taaaaccatc ctggaaactt aa                        4362


<210>  2424
<211>  2219
<212>  DNA
<213>  homo sapiens

<400>  2424
aaatctccct gagagcggga ccggcctcag ctccaacaca gcctccactg tgattaaaaa       60

taaaaattgc tagagcagcc ctcactcgcc acatctactt tgatagctgg ctatttggaa      120

tttaaaggat atttgacttt ttctaacctc ccatgaggct gtaagttcca ctgctccaaa      180

cccacccacc aaggactctg aacctgtcca ccccgggcgc atcaagatct tccagctggg      240

tacccccgat ttgggccgac tttgcacctc caaacaacct tagcatgatg tcttatctta      300

agcaaccgcc ttacgcagtc aatgggctga gtctgaccac ttcgggtatg gacttgctgc      360

acccctccgt gggctacccg gggccctggg cttcttgtcc cgcagccacc ccccggaaac      420

agcgccggga gaggacgacg ttcactcggg cgcagctaga tgtgctggaa gcactgtttg      480

ccaagacccg gtacccagac atcttcatgc gagaggaggt ggcactgaaa atcaacttgc      540

ccgagtcgag ggtgcaggta tggtttaaga atcgaagagc taagtgccgc caacaacagc      600

aacaacagca gaatggaggt caaaacaaag tgagacctgc caaaaagaag acatctccag      660

ctcgggaagt gagttcagag agtggaacaa gtggccaatt cactcccccc tctagcacct      720

cagtcccgac cattgccagc agcagtgctc ctgtgtctat ctggagccca gcttccatct      780

ccccactgtc agatcccttg tccacctcct cttcctgcat gcagaggtcc tatcccatga      840

cctatactca ggcttcaggt tatagtcaag gatatgctgg ctcaacttcc tactttgggg      900

gcatggactg tggatcatat ttgaccccta tgcatcacca gcttcccgga ccaggggcca      960

cactcagtcc catgggtacc aatgcagtca ccagccatct caatcagtcc ccagcttctc     1020

tttccaccca gggatatgga gcttcaagct tgggttttaa ctcaaccact gattgcttgg     1080

attataagga ccaaactgcc tcctggaagc ttaacttcaa tgctgactgc ttggattata     1140

aagatcagac atcctcgtgg aaattccagg ttttgtgaag acctgtagaa cctctttttg     1200

tgggtgattt ttaaatatac tgggctggac attccagttt tagccaggca ttggttaaaa     1260

gagttagatg ggatgatgct cagactcatc tgatcaaagt tccgagaggc atagaaggaa     1320

aaacgaaggg ccttagaggg gcctacaaac cagcaacatg aaatggacaa accaatctgc     1380

ttaagatcct gtcatagttt tagatcattg gttatcctga tttgcaaagt gatcaaaagc     1440

attctagcca tgtgcaacca aacaccacca aaaataaaat caaacaaaac taagttgtga     1500

aggaagggag ggaaggtcat agccttctta agcagaggtg ttccattgtt ttagccaatc     1560

cttggttgaa tcttaggaat gaacagtgtc tcaagctcat tcacgtttca tgaccaactg     1620

gtagttggca ctgaaaaaac ttttcagggc tgtgtgaatt gtgtgactga ttgtcctaga     1680

tgcactactt tatttaaaaa ataatgttca taaggagtca atatgtagtt taagagacaa     1740

tcagtgtgtg tcttataaat ggtacatctg tggtttttaa tctgtgctag acttcaaaac     1800

tgtgatctcc tgttattgta tgcaaccttg aactccacct ctgcaggggt tcttctgtga     1860

ttaaataggt tataattata agcaaaattc agagcaactg agtactgatc taaaaagatt     1920

acctttggct ggaggtgagc tgcactgaaa ctttacgaca aaatgtctct ggacaaagag     1980

agtcagagaa gagaagcaaa aggacactaa ttcatctgta atttactgtt ggtaagccta     2040

gcagtaaaga gacattggtc aattgctctg accctgatga attattaaac tgagatcatt     2100

gtcgtttatg cttgcagatg ttaaatggaa aagttatata tgcataaacc ttttcttcct     2160

ggatttggca gatatgtata attatattaa aatggttcta gcacaaaaaa aaaaaaaaa      2219


<210>  2425
<211>  2118
<212>  DNA
<213>  homo sapiens

<400>  2425
tttttaagtt agtgctggaa cgtggaagag ctgctgcctc cgaagcagta aaccagcccc       60

tctgtttgtt tgtttgcttt gcccttagtt ccactgctcc aaacccaccc accaaggact      120

ctgaacctgt ccaccccggg cgcatcaaga tcttccagct gggtaccccc gatttgggcc      180

gactttgcac ctccaaacaa ccttagcatg atgtcttatc ttaagcaacc gccttacgca      240

gtcaatgggc tgagtctgac cacttcgggt atggacttgc tgcacccctc cgtgggctac      300

ccggccaccc cccggaaaca gcgccgggag aggacgacgt tcactcgggc gcagctagat      360

gtgctggaag cactgtttgc caagacccgg tacccagaca tcttcatgcg agaggaggtg      420

gcactgaaaa tcaacttgcc cgagtcgagg gtgcaggtat ggtttaagaa tcgaagagct      480

aagtgccgcc aacaacagca acaacagcag aatggaggtc aaaacaaagt gagacctgcc      540

aaaaagaaga catctccagc tcgggaagtg agttcagaga gtggaacaag tggccaattc      600

actcccccct ctagcacctc agtcccgacc attgccagca gcagtgctcc tgtgtctatc      660

tggagcccag cttccatctc cccactgtca gatcccttgt ccacctcctc ttcctgcatg      720

cagaggtcct atcccatgac ctatactcag gcttcaggtt atagtcaagg atatgctggc      780

tcaacttcct actttggggg catggactgt ggatcatatt tgacccctat gcatcaccag      840

cttcccggac caggggccac actcagtccc atgggtacca atgcagtcac cagccatctc      900

aatcagtccc cagcttctct ttccacccag ggatatggag cttcaagctt gggttttaac      960

tcaaccactg attgcttgga ttataaggac caaactgcct cctggaagct taacttcaat     1020

gctgactgct tggattataa agatcagaca tcctcgtgga aattccaggt tttgtgaaga     1080

cctgtagaac ctctttttgt gggtgatttt taaatatact gggctggaca ttccagtttt     1140

agccaggcat tggttaaaag agttagatgg gatgatgctc agactcatct gatcaaagtt     1200

ccgagaggca tagaaggaaa aacgaagggc cttagagggg cctacaaacc agcaacatga     1260

aatggacaaa ccaatctgct taagatcctg tcatagtttt agatcattgg ttatcctgat     1320

ttgcaaagtg atcaaaagca ttctagccat gtgcaaccaa acaccaccaa aaataaaatc     1380

aaacaaaact aagttgtgaa ggaagggagg gaaggtcata gccttcttaa gcagaggtgt     1440

tccattgttt tagccaatcc ttggttgaat cttaggaatg aacagtgtct caagctcatt     1500

cacgtttcat gaccaactgg tagttggcac tgaaaaaact tttcagggct gtgtgaattg     1560

tgtgactgat tgtcctagat gcactacttt atttaaaaaa taatgttcat aaggagtcaa     1620

tatgtagttt aagagacaat cagtgtgtgt cttataaatg gtacatctgt ggtttttaat     1680

ctgtgctaga cttcaaaact gtgatctcct gttattgtat gcaaccttga actccacctc     1740

tgcaggggtt cttctgtgat taaataggtt ataattataa gcaaaattca gagcaactga     1800

gtactgatct aaaaagatta cctttggctg gaggtgagct gcactgaaac tttacgacaa     1860

aatgtctctg gacaaagaga gtcagagaag agaagcaaaa ggacactaat tcatctgtaa     1920

tttactgttg gtaagcctag cagtaaagag acattggtca attgctctga ccctgatgaa     1980

ttattaaact gagatcattg tcgtttatgc ttgcagatgt taaatggaaa agttatatat     2040

gcataaacct tttcttcctg gatttggcag atatgtataa ttatattaaa atggttctag     2100

cacaaaaaaa aaaaaaaa                                                   2118


<210>  2426
<211>  2219
<212>  DNA
<213>  homo sapiens

<400>  2426
aaatctccct gagagcggga ccggcctcag ctccaacaca gcctccactg tgattaaaaa       60

taaaaattgc tagagcagcc ctcactcgcc acatctactt tgatagctgg ctatttggaa      120

tttaaaggat atttgacttt ttctaacctc ccatgaggct gtaagttcca ctgctccaaa      180

cccacccacc aaggactctg aacctgtcca ccccgggcgc atcaagatct tccagctggg      240

tacccccgat ttgggccgac tttgcacctc caaacaacct tagcatgatg tcttatctta      300

agcaaccgcc ttacgcagtc aatgggctga gtctgaccac ttcgggtatg gacttgctgc      360

acccctccgt gggctacccg gggccctggg cttcttgtcc cgcagccacc ccccggaaac      420

agcgccggga gaggacgacg ttcactcggg cgcagctaga tgtgctggaa gcactgtttg      480

ccaagacccg gtacccagac atcttcatgc gagaggaggt ggcactgaaa atcaacttgc      540

ccgagtcgag ggtgcaggta tggtttaaga atcgaagagc taagtgccgc caacaacagc      600

aacaacagca gaatggaggt caaaacaaag tgagacctgc caaaaagaag acatctccag      660

ctcgggaagt gagttcagag agtggaacaa gtggccaatt cactcccccc tctagcacct      720

cagtcccgac cattgccagc agcagtgctc ctgtgtctat ctggagccca gcttccatct      780

ccccactgtc agatcccttg tccacctcct cttcctgcat gcagaggtcc tatcccatga      840

cctatactca ggcttcaggt tatagtcaag gatatgctgg ctcaacttcc tactttgggg      900

gcatggactg tggatcatat ttgaccccta tgcatcacca gcttcccgga ccaggggcca      960

cactcagtcc catgggtacc aatgcagtca ccagccatct caatcagtcc ccagcttctc     1020

tttccaccca gggatatgga gcttcaagct tgggttttaa ctcaaccact gattgcttgg     1080

attataagga ccaaactgcc tcctggaagc ttaacttcaa tgctgactgc ttggattata     1140

aagatcagac atcctcgtgg aaattccagg ttttgtgaag acctgtagaa cctctttttg     1200

tgggtgattt ttaaatatac tgggctggac attccagttt tagccaggca ttggttaaaa     1260

gagttagatg ggatgatgct cagactcatc tgatcaaagt tccgagaggc atagaaggaa     1320

aaacgaaggg ccttagaggg gcctacaaac cagcaacatg aaatggacaa accaatctgc     1380

ttaagatcct gtcatagttt tagatcattg gttatcctga tttgcaaagt gatcaaaagc     1440

attctagcca tgtgcaacca aacaccacca aaaataaaat caaacaaaac taagttgtga     1500

aggaagggag ggaaggtcat agccttctta agcagaggtg ttccattgtt ttagccaatc     1560

cttggttgaa tcttaggaat gaacagtgtc tcaagctcat tcacgtttca tgaccaactg     1620

gtagttggca ctgaaaaaac ttttcagggc tgtgtgaatt gtgtgactga ttgtcctaga     1680

tgcactactt tatttaaaaa ataatgttca taaggagtca atatgtagtt taagagacaa     1740

tcagtgtgtg tcttataaat ggtacatctg tggtttttaa tctgtgctag acttcaaaac     1800

tgtgatctcc tgttattgta tgcaaccttg aactccacct ctgcaggggt tcttctgtga     1860

ttaaataggt tataattata agcaaaattc agagcaactg agtactgatc taaaaagatt     1920

acctttggct ggaggtgagc tgcactgaaa ctttacgaca aaatgtctct ggacaaagag     1980

agtcagagaa gagaagcaaa aggacactaa ttcatctgta atttactgtt ggtaagccta     2040

gcagtaaaga gacattggtc aattgctctg accctgatga attattaaac tgagatcatt     2100

gtcgtttatg cttgcagatg ttaaatggaa aagttatata tgcataaacc ttttcttcct     2160

ggatttggca gatatgtata attatattaa aatggttcta gcacaaaaaa aaaaaaaaa      2219


<210>  2427
<211>  2287
<212>  DNA
<213>  homo sapiens

<400>  2427
ttctcgccac gcacctgcgt cagctcgctc tgcgcgtgcg ccggtggcgg gactctgggg       60

aaaatggctg cgtcttcgag tggtgagaag gagaaggagc ggctgggagg cggtttggga      120

gtggcgggtg gtaacagcac acgagagcgg ctgctgtctg cgcttgagga cttggaggtc      180

ctgtctaggg aacttataga aatgctggca atttcaagaa accaaaagtt gttacaggct      240

ggagaggaaa accaggtcct ggagttgtta attcaccgag atggggaatt tcaagaacta      300

atgaaattgg cacttaatca gggaaaaatt catcatgaaa tgcaagtttt agaaaaagaa      360

gtagagaaga gagacagtga tattcagcag ctacaaaaac agctaaagga agcagaacaa      420

atactggcaa cagctgttta ccaagcgaag gagaaactca agtcaataga aaaagcaaga      480

aaaggtgcta tctcctctga agaaataatt aagtatgcac ataggatcag tgcaagtaat      540

gctgtatgtg ctccactgac ctgggttcca ggggaccccc ggagacccta cccaactgat      600

ttagagatga gaagtgggtt actgggtcag atgaacaatc cttccactaa tggcgtgaat      660

ggccatttac caggagatgc acttgcagca ggaagattgc cagatgtcct tgctccacag      720

tatccatggc agtcaaatga catgtcgatg aatatgttac caccaaatca tagtagtgac      780

tttttgttgg aacctcctgg gcataataaa gaaaatgaag atgatgtaga gattatgtca      840

acggactcct caagcagtag tagtgagtct gattgaaaaa ccttaaaaga caatatacag      900

aattgaatac tgtagaattc tgtttcttta acagtagcag ggaaatgtaa actacaggtg      960

acaaaaaata cccaggtaaa cactggcttt ggtagaattg tgcagtcatt aaaagtcaaa     1020

attttttgac tttcttttta aagccaaaga ccatagtttt agttttaagc cactaggtag     1080

atatttaggg gaatagtcaa aatttactgt tgaaaaagca gttgctatgt gctttcttac     1140

cctgttctgt tccagttttg ctggatttgt acatagccat tctagaaata gagttgaggg     1200

aaattatcca tatacatatc actaataggc ttcttggaat tatttagaaa agcattttta     1260

aactggcagt ggatgactga ataggcatca tatttctttt tgtgtgtcat ttaaaagtaa     1320

caaaaactgc catttgacag taaaggctct tggcttctgt tggaggcatg ggaaattgtc     1380

tcaatttgta cagtttgtaa ttgtaatttt tgtaaataaa tttgtttgta cattgtatgc     1440

ttttttttta gtttaaatat actgtcagtg taggtaggaa attatttctg taaatccagt     1500

tgcattttat aatacttgag tgactaactg aattgaaacc tattacaatt aatagggttc     1560

tcaaaggcct attcctatta gaagaaataa ttttttttaa taattgaaaa aatttaccac     1620

agccttgtct gattttaaga atagattgtg tgaagattta gaatggaaag caaccatttc     1680

ttcccttcac cttcctcttc ttacagttcc ccaggagtca tttttaacca cttttaattt     1740

ctgttggtaa cctctgtgtt taggtaatat gcttatacaa ctatttcttg atgtatcagt     1800

tttagacaat gtatcttctg atttcaaagg taatacaaca tttaatgtga aacatttagt     1860

gaatacagta aaggagaaaa taaaattgtt agcattctac ccagagataa tatcaattca     1920

tattgtagtg tagatttttt taaagttcac atacactttt ttgtaaaatg agaataatgt     1980

ttatttcctg agatactgct gtatttttta attgctaatc tgtattcttc aaatgaactg     2040

agaattccat ttttccatca ttttttcctt ttgattattt tcgatctcta gaaaaattgg     2100

aaaataggag attaatctta tattttcacc atctagaatt aaggacatac aatgtttgaa     2160

tgtctttccc tccagggtta tttttaggaa tggactaaca caatatctaa ttttaacctt     2220

gccttgtccg tatactagga atattgatcc atgtgtatac attcttgaaa gatttacttt     2280

aatggct                                                               2287


<210>  2428
<211>  4523
<212>  DNA
<213>  homo sapiens

<400>  2428
gcagttcagc gagatgaaag ggataaagca gaacccgctg gcactaggaa aagcttccaa       60

cacacagtcc acaacacagc ttgggaacca aaaaagctac agatccagcc actcagccca      120

agcatgggag aactaccagc attgcctcat tgcaaaaaag aggaggaaaa caacgtgatc      180

catgtttaac aaaagagtct gtggactagg aggtgggagg gtaactacct gctgaaagtg      240

aactttcttt gatatccatg catatatata aactcagccc tgcctttgat gttcagcaac      300

tgattcactg atcagattac aggcatttca tctccctgct cgtctgcctt tgatctgcat      360

ggttaatttt attttcctgg atttgaagtt tcgtctgggc ttgtgctgac atacattttt      420

gggaaggtag aagcatttgg cacagaagtg ctgccaggag aaactaagtt gctgaacgga      480

actctccaac aataaataca tttgataaga aagatggctt taaaagtgct actagaacaa      540

gagaaaacgt ttttcactct tttagtatta ctaggctatt tgtcatgtaa agtgacttgt      600

gaatcaggag actgtagaca gcaagaattc agggatcggt ctggaaactg tgttccctgc      660

aaccagtgtg ggccaggcat ggagttgtct aaggaatgtg gcttcggcta tggggaggat      720

gcacagtgtg tgacgtgccg gctgcacagg ttcaaggagg actggggctt ccagaaatgc      780

aagccctgtc tggactgcgc agtggtgaac cgctttcaga aggcaaattg ttcagccacc      840

agtgatgcca tctgcgggga ctgcttgcca ggattttata ggaagacgaa acttgtcggc      900

tttcaagaca tggagtgtgt gccttgtgga gaccctcctc ctccttacga accgcactgt      960

gccagcaagg tcaacctcgt gaagatcgcg tccacggcct ccagcccacg ggacacggcg     1020

ctggctgccg ttatctgcag cgctctggcc accgtcctgc tggccctgct catcctctgt     1080

gtcatctatt gtaagagaca gtttatggag aagaaaccca gctggtctct gcggtcacag     1140

gacattcagt acaacggctc tgagctgtcg tgttttgaca gacctcagct ccacgaatat     1200

gcccacagag cctgctgcca gtgccgccgt gactcagtgc agacctgcgg gccggtgcgc     1260

ttgctcccat ccatgtgctg tgaggaggcc tgcagcccca acccggcgac tcttggttgt     1320

ggggtgcatt ctgcagccag tcttcaggca agaaacgcag gcccagccgg ggagatggtg     1380

ccgactttct tcggatccct cacgcagtcc atctgtggcg agttttcaga tgcctggcct     1440

ctgatgcaga atcccatggg tggtgacaac atctcttttt gtgactctta tcctgaactc     1500

actggagaag acattcattc tctcaatcca gaacttgaaa gctcaacgtc tttggattca     1560

aatagcagtc aagatttggt tggtggggct gttccagtcc agtctcattc tgaaaacttt     1620

acagcagcta ctgatttatc tagatataac aacacactgg tagaatcagc atcaactcag     1680

gatgcactaa ctatgagaag ccagctagat caggagagtg gtgctgtcat ccacccagcc     1740

actcagacgt ccctccagga agcttaaaga acctgcttct ttctgcagta gaagcgtgtg     1800

ctggaaccca aagagtactc ctttgttagg cttatggact gagcagtctg gaccttgcat     1860

ggcttctggg gcaaaaataa atctgaacca aactgacggc atttgaagcc tttcagccag     1920

ttgcttctga gccagaccag ctgtaagctg aaacctcaat gaataacaag aaaagactcc     1980

aggccgactc atgatactct gcatctttcc tacatgagaa gcttctctgc cacaaaagtg     2040

acttcaaaga cggatgggtt gagctggcag cctatgagat tgtggacata taacaagaaa     2100

cagaaatgcc ctcatgctta ttttcatggt gattgtggtt ttacaagact gaagacccag     2160

agtatacttt ttctttccag aaataatttc ataccgccta tgaaatatca gataaattac     2220

cttagctttt atgtagaatg ggttcaaaag tgagtgtttc tatttgagaa ggacactttt     2280

tcatcatcta aactgattcg cataggtggt tagaatggcc ctcatattgc ctgcctaaat     2340

cttgggttta ttagatgaag tttactgaat cagaggaatc agacagagga ggatagctct     2400

ttccagaatc cacacttctg acctcagcct cggtctcatg aacacccgct gatctcagga     2460

gaacacctgg gctagggaat gtggtcgaga aagggcagcc cattgcccag aattaacaca     2520

tattgtagag acttgtatgc aaaggttggc atatttatat gaaaattagt tgctatagaa     2580

acatttgttg catctgtccc tctgcctgag cttagaaggt tatagaaaaa gggtatttat     2640

aaacataaat gaccttttac ttgcattgta tcttatacta aaggctttag aaattacaac     2700

atatcaggtt cccctactac tgaagtagcc ttccgtgaga acacaccaca tgttaggact     2760

agaagaaaat gcacaatttg taggggtttg gatgaagcag ctgtaactgc cctagtgtag     2820

tttgaccagg acattgtcgt gctccttcca attgtgtaag attagttagc acatcatctc     2880

ctactttagc catccggtgt tggatttaag aggacggtgc ttctttctat taaagtgctc     2940

catcccctac catctacaca ttagcattgt ctctagagct aagacagaaa ttaaccccgt     3000

tcagtcacaa agcagggaat ggttcattta ctcttaatct ttatgccctg gagaagacct     3060

acttgaacag ggcatatttt ttagacttct gaacatcagt atgttcgagg gtactatgat     3120

attttggttt ggaattgccc tgcccaagtc actgtctttt aacttttaaa ctgaatatta     3180

aaatgtatct gtctttccta gtatgttttt atcttctcat gtattatcca tggttttctc     3240

tgtttgtgac agattagtaa aatttaatga gccctctttc ttgtggccgt ttctccatag     3300

ttttaggttt tgatatgtgt ttactagctt gcctgtgtct ggtacatctc atgacctcaa     3360

ttccctcacc tgaaatagga aatgagaatg tttcattgta gccccaagcg gtcatgtcaa     3420

cctagtgcct agtcataatt aattgacttt tcctgtatta cttctttttt taagtataaa     3480

ccaatgatcc tttggtagtc aagaactctt aggaacattg ccttttggac atgtaaaata     3540

tttaggattt gaccacacaa tggctatgaa aatgcaagta gtttcctcgc gtgacctcac     3600

catgattcac atacgtgcca ctgtttgaaa tctggtctgt ttgcatttct gttatgacag     3660

agagatgatg tttgcatttc tgttatgaca gagagatgat gaaagtaggc agggctgtgt     3720

tcctttgtgt agcctgtata tattttccat atgtagagcc ctgattaact tcaaggacaa     3780

acactggctg gagaaagcca gactgatggg aatgagactt tggccaaaaa tcccaaaaca     3840

tcattttcaa tcagtagaga agtgcttagg gttgaaaatt gatttcattt gctactgaat     3900

ttggtaaatc ctgggtaact tttatcaaga tgaagacatt ttaccctacc tactctagaa     3960

atatacaaca atgttatatt ttacactcct tggaaacatt tgaggaaaaa aatgcaattt     4020

gcacttcact ttgttggaat atcccatagc actcaataaa ctcagctgct agagtgccga     4080

tgtcaggagg gctgtgtcgg gtaatgcgtg tggctgaatg ggcataacca ctgtggcttc     4140

ttgtgctgca gaagctcgtt gacaagactg aggaggattt caagagcaac caagtaaagt     4200

catgaatttt ctaattttgt gtatatggaa tatattttta aatagagatt tttctacttt     4260

agataatgtg ttaatattgc tattacctag gttaagcact attgtctgtg ctagtaagaa     4320

aaagaaagga aaaccatcat tgctttatag tagcttatat caatttagat ttcatcatta     4380

ctattttgca tactggaatt tataaatgtg taaattatca ttttcttagt tttgtaatac     4440

cttttttatt tgtgaataaa attatcacct ggtattctta tttatgtgtt caaaaaaaaa     4500

aaaaaaaaaa aaaaaaaaaa aaa                                             4523


<210>  2429
<211>  4201
<212>  DNA
<213>  homo sapiens

<400>  2429
gggggcgcgg ccgcgctcgt ctcgccgggc tgttcgcggg caggccctgc cctgaaggga       60

cgaatcggct tggagcgcgg gaggtggagt cggccccggc ggtcgctccc tggacccaac      120

ccgaggctga cccaggcccc tgcccatgcg gggcgcccct ggctcggaag agtcccccgg      180

gccgggagca gctccaggca gcggccccgg aggaagagga agaagggaca gtgctcagct      240

tgggggaccc ggaccctcgc cgcggcattt ggagccgggg gcagtcccga actctgtgct      300

tggcaccgcc gctccgagta gggcagcgcc tgccgggacc ctgacccgga ccccctgcgc      360

ctcgtaggcg gcggcgccgc cgcgccaccc tgttcttccg tgtctccctc tgcctggcgg      420

cagtcacggc caagaaccta cattaagaaa cgcattcaga tgcatcagcc gtttgtaaag      480

cacctgtcgt gagccagaga gtattatgag ggaggccgag gacttcatgc tccggacaga      540

gaaacggcgc tgggattagg gattgccact tctgagagga tgctgggaat ctgcaggggg      600

agacggaaat tcttggctgc ctcgttgagt cttctctgca tcccagccat cacctggatt      660

tacctgtttt ctgggagctt cgaagatgga aagcccgtgt ctctgtcacc gctggagtcc      720

caggcacaca gccccaggta cacggcctcc agccagcggg agcgcgagag cctggaggtg      780

cgcatgcgcg aggtggagga ggagaaccgc gccctccgca ggcagctcag cctggcccag      840

ggccgagccc catcccatcg ccgaggcaac cactccaaga cctactccat ggaggagggc      900

actggagaca gcgagaacct tcgggctggc atcgtggcag gcaacagctc cgagtgtggg      960

cagcagccgg tcgtggagaa atgcgagaca atccacgttg ctattgtctg cgccggatac     1020

aatgccagcc gggatgtcgt caccctggtc aaatccgtcc tgttccatag acggaaccct     1080

ctgcacttcc accttattgc tgactccatt gcggagcaga tcctggccac gctcttccag     1140

acctggatgg tgcccgctgt gcgtgtggac ttctacaatg cagacgagct caagtctgaa     1200

gtttcctgga tccccaataa acattactct gggatttatg gtctgatgaa gcttgtcctg     1260

accaagactc ttcctgccaa cctggagaga gtcatcgtcc ttgacacgga tatcaccttt     1320

gccactgaca ttgcagagct gtgggctgtg ttccacaagt tcaaaggtca gcaagtcctg     1380

ggcttggtgg agaaccagag tgactggtac cttggaaacc tgtggaaaaa tcaccgccca     1440

tggccagccc ttggaagagg ctacaacaca ggggtgatcc tgttacttct ggataagctg     1500

cggaagatga aatgggagca gatgtggagg ctgaccgcag agagggagct catgggcatg     1560

ctctctacat ccttagctga ccaggatatt ttcaatgccg tcatcaaaca aaaccccttc     1620

cttgtgtacc agctcccctg cttctggaat gtgcagctgt cagaccacac ccgctccgag     1680

cagtgctaca gagacgtgtc tgatctaaag gtcattcact ggaactcccc caagaagctc     1740

cgggtgaaga acaagcatgt ggagtttttt cgcaacctct acctgacctt cctggagtat     1800

gacggcaatc ttctgaggcg ggaactgttt ggctgcccca gtgaggctga tgtcaacagt     1860

gaaaacctcc agaagcagct gtctgagctg gacgaggacg acctgtgcta tgagttccgg     1920

cgagagcgct tcactgtcca ccgcacccac ctgtacttcc tgcactacga gtatgagcct     1980

gcagcagaca gcacggacgt caccctggtc gctcagctgt ccatggacag gctccagatg     2040

ctggaggcca tctgcaagca ctgggagggg cccatcagcc tggccctcta cctgtcagac     2100

gccgaggccc agcagttcct ccgctacgca cagggctctg aggtgcttat gagccgccac     2160

aacgtgggct accacatcgt gtacaaggag ggccagttct accccgtgaa cctgctgcgc     2220

aacgtggcca tgaagcacat cagcactccc tacatgttcc tgtctgacat tgacttcctg     2280

cccatgtatg ggctctatga gtacctcagg aagtctgtca tccagctcga tcttgccaac     2340

accaagaaag caatgattgt ccccgcgttc gagacactgc gctaccggct gtccttcccc     2400

aagtcaaaag cggagttgct gtcaatgctg gacatgggga ccctcttcac attcaggtac     2460

cacgtctgga cgaaaggcca cgcacccaca aacttcgcca agtggcggac cgccaccacg     2520

ccttaccggg ttgagtggga ggccgatttt gagccgtatg ttgttgtgag acgtgactgc     2580

ccggagtacg accggaggtt tgtaggcttt ggctggaaca aagtggctca tatcatggag     2640

ctggatgtgc aggagtatga gttcattgtg ctgcccaacg cctacatgat ccacatgcct     2700

catgccccca gcttcgacat taccaagttc cgttccaaca agcaataccg catctgtctc     2760

aaaaccctca aggaagagtt tcagcaggac atgtcccgcc gctacggctt tgctgccctg     2820

aaatatctca cagccgagaa caacagctag caccaagaag cccaccacta gggggagaca     2880

tgctgtaggg gaagtgccac tcgctgtttg gggcccggcc ttcaaattca aaattgagcc     2940

atgctttttc ggtttgtttt tatttatctc tttggcccag ccaagctgcc ctcactacag     3000

agaccttgga caaggatcca gccagtccct ctctgcccca caaccctgca ttcccagagg     3060

ttagctatgc agcccaccta gatgagtctc ttcaagaatg ggaaatcaag gggtgacagg     3120

gagtaaaagg gttatcatct tactgcaaag ccacaagatc agggcagggc tttaggatgt     3180

tctggatgct ttttaataat tatgcttccc atcataactg gggagaaagg gaagtcaggg     3240

ttctaggggt tattcgtccc aggaaataga agtgaaattg tctttattaa gtgaaaactt     3300

tcccctttgc cctgcaatgt agctgggcat tcaaacggag ggcaaaccga tgatctaaac     3360

caaccacttg gaaaaaccca atggggacat tgtaaccaga gggtcctgga ggtggggttg     3420

atgggtttcc ttatccccaa agtcactcct gttttgtttt gtttttcttt gggggttttg     3480

tttatttttg gggctggcaa tccaaaatag aaaatctgat cctttgaggc tctaaaggaa     3540

aatcagctgc ctctaccaac caccctctat cagcagtggc ccaggaagga ggtcaagcat     3600

cttcggccga tatttaaaca tgggcagctt ccttcaggat gatcaccgag gctcccgtga     3660

ctttgaactc cctactctcc agaatccagg ggctatagcg atggggactg cggaattacg     3720

agggctggct gttttacacc ggtcacattt tctattggca gtgactgatt catgggaaag     3780

ggctttgaag gaactacttc agtgcacaca caaggtacga acctctcagg cctttcgaag     3840

aactttcata attcatgaaa gcccagttct gaagattcac gtatccatct ggagacctac     3900

aggaagaaag tgattgggtt cctctggttc ttgcctgctt cactgtggat gggaagaggt     3960

gacaacctca gtctcccttt gggacctgtc caagggtagg caaccacctt caccttcaca     4020

cagattgagg agacactgga ctttttaccc attttcttta atcttcaata ttaatattgt     4080

gtttacattg atgagaacaa gagttaatgc cctaccctct gctgggctgt ttgtattgag     4140

ttgcaatgtg accagcgaaa gctgcattta ataaatgaaa gtacagactg tttcttcccc     4200

a                                                                     4201


<210>  2430
<211>  4404
<212>  DNA
<213>  homo sapiens

<400>  2430
aggattgggg gtcccagcct gcgtcccgtc agtcccttct tggcccggag tgcgcggagc       60

tgggagtggc ttcgccatgg ctgtgagaag ggactccgtg tggaagtact gctggggtgt      120

tttgatggtt ttatgcagaa ctgcgatttc caaatcgata gttttagagc ctatctattg      180

gaattcctcg aactccaaat ttctacctgg acaaggactg gtactatacc cacagatagg      240

agacaaattg gatattattt gccccaaagt ggactctaaa actgttggcc agtatgaata      300

ttataaagtt tatatggttg ataaagacca agcagacaga tgcactatta agaaggaaaa      360

tacccctctc ctcaactgtg ccaaaccaga ccaagatatc aaattcacca tcaagtttca      420

agaattcagc cctaacctct ggggtctaga atttcagaag aacaaagatt attacattat      480

atctacatca aatgggtctt tggagggcct ggataaccag gagggagggg tgtgccagac      540

aagagccatg aagatcctca tgaaagttgg acaagatgca agttctgctg gatcaaccag      600

gaataaagat ccaacaagac gtccagaact agaagctggt acaaatggaa gaagttcgac      660

aacaagtccc tttgtaaaac caaatccagg ttctagcaca gacggcaaca gcgccggaca      720

ttcggggaac aacatcctcg gttccgaagt ggccttattt gcagggattg cttcaggatg      780

catcatcttc atcgtcatca tcatcacgct ggtggtcctc ttgctgaagt accggaggag      840

acacaggaag cactcgccgc agcacacgac cacgctgtcg ctcagcacac tggccacacc      900

caagcgcagc ggcaacaaca acggctcaga gcccagtgac attatcatcc cgctaaggac      960

tgcggacagc gtcttctgcc ctcactacga gaaggtcagc ggggactacg ggcacccggt     1020

gtacatcgtc caggagatgc ccccgcagag cccggcgaac atttactaca aggtctgaga     1080

gggaccctgg tggtacctgt gctttcccag aggacaccta atgtcccgat gcctcccttg     1140

agggtttgag agcccgcgtg ctggagaatt gactgaagca cagcaccggg ggagagggac     1200

actcctcctc ggaagagccc gtcgcgctgg acagcttacc tagtcttgta gcattcggcc     1260

ttggtgaaca cacacgctcc ctggaagctg gaagactgtg cagaagacgc ccattcggac     1320

tgctgtgccg cgtcccacgt ctcctcctcg aagccatgtg ctgcggtcac tcaggcctct     1380

gcagaagcca agggaagaca gtggtttgtg gacgagaggg ctgtgagcat cctggcaggt     1440

gccccaggat gccacgcctg gaagggccgg cttctgcctg gggtgcattt cccccgcagt     1500

gcataccgga cttgtcacac ggacctcggg ctagttaagg tgtgcaaaga tctctagagt     1560

ttagtcctta ctgtctcact cgttctgtta cccagggctc tgcagcacct cacctgagac     1620

ctccactcca catctgcatc actcatggaa cactcatgtc tggagtcccc tcctccagcc     1680

gctggcaaca acagcttcag tccatgggta atccgttcat agaaattgtg tttgctaaca     1740

aggtgccctt tagccagatg ctaggctgtc tgcgaagaag gctaggagtt catagaaggg     1800

agtggggctg gggaaagggc tggctgcaat tgcagctcac tgctgctgcc tctgaaacag     1860

aaagttggaa aggaaaaaag aaaaaagcaa ttaggtagca cagcactttg gttttgctga     1920

gatcgaagag gccagtagga gacacgacag cacacacagt ggattccagt gcatggggag     1980

gcactcgctg ttatcaaata gcgatgtgca ggaagaaaag cccctcttca ttccggggaa     2040

caaagacggg tattgttggg aaaggaacag gcttggaggg aagggagaaa gtaggccgct     2100

gatgatatat tcgggcagga ctgttgtggt actggcaata agatacacag ctccgagctg     2160

taggagagtc ggtctgcttt ggatgatttt ttaagcagac tcagctgcta tacttatcac     2220

attttattaa acacagggaa agcatttagg agaatagcag agagccaaat ctgacctaaa     2280

agttgaaaag ccaaaggtca aacaggctgt aattccatca tcatcgttgt tattaaagaa     2340

tccttatcta taaaaggtag gtcagatccc cctcccccca ggttcctcct tcccctcccg     2400

attgagcctt acgacacttt ggtttatgcg gtgctgtccg ggtgccaggg ctgcagggtc     2460

ggtactgatg gaggctgcag cgcccggtgc tctgtgtcaa ggtgaagcac atacggcaga     2520

cctcttagag tccttaagac ggaagtaaat tatgatgtcc agggggagaa ggaagatagg     2580

acgtatttat aataggtata tagaacacaa gggatataaa atgaaagatt tttactaata     2640

tatattttaa ggttgcacac agtacacacc agaagatgtg aaattcattt gtggcaatta     2700

agtggtccca atgctcagcg cttaaaaaaa caaattggac agctacttct gggaaaaaca     2760

acatcattcc aaaaagaaca ataatgagag caaatgcaaa aataaccaag tcctccgaag     2820

gcatctcacg gaaccgtaga ctaggaagta cgagccccac agagcaggaa gccgatgtga     2880

ctgcatcata tatttaacaa tgacaagatg ttccggcgtt tatttctgcg ttgggttttc     2940

ccttgcctta tgggctgaag tgttctctag aatccagcag gtcacactgg gggcttcagg     3000

tgacgattta gctgtggctc cctcctcctg tcctcccccg caccccctcc cttctgggaa     3060

acaagaagag taaacaggaa acctactttt tatgtgctat gcaaaataga catctttaac     3120

atagtcctgt tactatggta acactttgct ttctgaattg gaagggaaaa aaaatgtagc     3180

gacagcattt taaggttctc agacctccag tgagtacctg caaaaatgag ttgtcacaga     3240

aattatgatc ctctatttcc tgaacctgga aatgatgttg gtccaaagtg cgtgtgtgta     3300

tgtgtgagtg ggtgcgtggt atacatgtgt acatatatgt ataatatata tctacaatat     3360

atattatata tatctatatc atatttctgt ggagggttgc catggtaacc agccacagta     3420

catatgtaat tctttccatc accccaacct ctcctttctg tgcattcatg caagagtttc     3480

ttgtaagcca tcagaagtta cttttaggat gggggagagg ggcgagaagg ggaaaaatgg     3540

gaaatagtct gattttaatg aaatcaaatg tatgtatcat cagttggcta cgttttggtt     3600

ctatgctaaa ctgtgaaaaa tcagatgaat tgataaaaga gttccctgca accaattgaa     3660

aagtgttctg tgcgtctgtt ttgtgtctgg tgcagaatat gacaatctac caactgtccc     3720

tttgtttgaa gttggtttag ctttggaaag ttactgtaaa tgccttgctt gtatgatcgt     3780

ccctggtcac ccgactttgg aatttgcacc atcatgtttc agtgaagatg ctgtaaatag     3840

gttcagattt tactgtctat ggatttgggg tgttacagta gccttattca cctttttaat     3900

aaaaatacac atgaaaacaa gaaagaaatg gcttttctta cccagattgt gtacatagag     3960

caatgttggt tttttataaa gtctaagcaa gatgttttgt ataaaatctg aattttgcaa     4020

tgtatttagc tacagcttgt ttaacggcag tgtcattccc ctttgcactg taatgaggaa     4080

aaaatggtat aaaaggttgc caaattgctg catatttgtg ccgtaattat gtaccatgaa     4140

tatttattta aaatttcgtt gtccaatttg taagtaacac agtattatgc ctgagttata     4200

aatatttttt tctttctttg ttttatttta atagcctgtc ataggtttta aatctgcttt     4260

agtttcacat tgcagttagc cccagaaaat gaaatccgtg aagtcacatt ccacatctgt     4320

ttcaaactga atttgttctt aaaaaaataa aatatttttt tcctatggaa aaagtgcctt     4380

caaagtaaaa aaaaaaaaaa aaaa                                            4404


<210>  2431
<211>  5600
<212>  DNA
<213>  homo sapiens

<400>  2431
aaaaagagaa actgttggga gaggaatcgt atctccatat ttcttctttc agccccaatc       60

caagggttgt agctggaact ttccatcagt tcttcctttc tttttcctct ctaagccttt      120

gccttgctct gtcacagtga agtcagccag agcagggctg ttaaactctg tgaaatttgt      180

cataagggtg tcaggtattt cttactggct tccaaagaaa catagataaa gaaatctttc      240

ctgtggcttc ccttggcagg ctgcattcag aaggtctctc agttgaagaa agagcttgga      300

ggacaacagc acaacaggag agtaaaagat gccccagggc tgaggcctcc gctcaggcag      360

ccgcatctgg ggtcaatcat actcaccttg cccgggccat gctccagcaa aatcaagctg      420

ttttcttttg aaagttcaaa ctcatcaaga ttatgctgct cactcttatc attctgttgc      480

cagtagtttc aaaatttagt tttgttagtc tctcagcacc gcagcactgg agctgtcctg      540

aaggtactct cgcaggaaat gggaattcta cttgtgtggg tcctgcaccc ttcttaattt      600

tctcccatgg aaatagtatc tttaggattg acacagaagg aaccaattat gagcaattgg      660

tggtggatgc tggtgtctca gtgatcatgg attttcatta taatgagaaa agaatctatt      720

gggtggattt agaaagacaa cttttgcaaa gagtttttct gaatgggtca aggcaagaga      780

gagtatgtaa tatagagaaa aatgtttctg gaatggcaat aaattggata aatgaagaag      840

ttatttggtc aaatcaacag gaaggaatca ttacagtaac agatatgaaa ggaaataatt      900

cccacattct tttaagtgct ttaaaatatc ctgcaaatgt agcagttgat ccagtagaaa      960

ggtttatatt ttggtcttca gaggtggctg gaagccttta tagagcagat ctcgatggtg     1020

tgggagtgaa ggctctgttg gagacatcag agaaaataac agctgtgtca ttggatgtgc     1080

ttgataagcg gctgttttgg attcagtaca acagagaagg aagcaattct cttatttgct     1140

cctgtgatta tgatggaggt tctgtccaca ttagtaaaca tccaacacag cataatttgt     1200

ttgcaatgtc cctttttggt gaccgtatct tctattcaac atggaaaatg aagacaattt     1260

ggatagccaa caaacacact ggaaaggaca tggttagaat taacctccat tcatcatttg     1320

taccacttgg tgaactgaaa gtagtgcatc cacttgcaca acccaaggca gaagatgaca     1380

cttgggagcc tgagcagaaa ctttgcaaat tgaggaaagg aaactgcagc agcactgtgt     1440

gtgggcaaga cctccagtca cacttgtgca tgtgtgcaga gggatacgcc ctaagtcgag     1500

accggaagta ctgtgaagat gttaatgaat gtgctttttg gaatcatggc tgtactcttg     1560

ggtgtaaaaa cacccctgga tcctattact gcacgtgccc tgtaggattt gttctgcttc     1620

ctgatgggaa acgatgtcat caacttgttt cctgtccacg caatgtgtct gaatgcagcc     1680

atgactgtgt tctgacatca gaaggtccct tatgtttctg tcctgaaggc tcagtgcttg     1740

agagagatgg gaaaacatgt agcggttgtt cctcacccga taatggtgga tgtagccagc     1800

tctgcgttcc tcttagccca gtatcctggg aatgtgattg ctttcctggg tatgacctac     1860

aactggatga aaaaagctgt gcagcttcag gaccacaacc atttttgctg tttgccaatt     1920

ctcaagatat tcgacacatg cattttgatg gaacagacta tggaactctg ctcagccagc     1980

agatgggaat ggtttatgcc ctagatcatg accctgtgga aaataagata tactttgccc     2040

atacagccct gaagtggata gagagagcta atatggatgg ttcccagcga gaaaggctta     2100

ttgaggaagg agtagatgtg ccagaaggtc ttgctgtgga ctggattggc cgtagattct     2160

attggacaga cagagggaaa tctctgattg gaaggagtga tttaaatggg aaacgttcca     2220

aaataatcac taaggagaac atctctcaac cacgaggaat tgctgttcat ccaatggcca     2280

agagattatt ctggactgat acagggatta atccacgaat tgaaagttct tccctccaag     2340

gccttggccg tctggttata gccagctctg atctaatctg gcccagtgga ataacgattg     2400

acttcttaac tgacaagttg tactggtgcg atgccaagca gtctgtgatt gaaatggcca     2460

atctggatgg ttcaaaacgc cgaagactta cccagaatga tgtaggtcac ccatttgctg     2520

tagcagtgtt tgaggattat gtgtggttct cagattgggc tatgccatca gtaatgagag     2580

taaacaagag gactggcaaa gatagagtac gtctccaagg cagcatgctg aagccctcat     2640

cactggttgt ggttcatcca ttggcaaaac caggagcaga tccctgctta tatcaaaacg     2700

gaggctgtga acatatttgc aaaaagaggc ttggaactgc ttggtgttcg tgtcgtgaag     2760

gttttatgaa agcctcagat gggaaaacgt gtctggctct ggatggtcat cagctgttgg     2820

caggtggtga agttgatcta aagaaccaag taacaccatt ggacatcttg tccaagacta     2880

gagtgtcaga agataacatt acagaatctc aacacatgct agtggctgaa atcatggtgt     2940

cagatcaaga tgactgtgct cctgtgggat gcagcatgta tgctcggtgt atttcagagg     3000

gagaggatgc cacatgtcag tgtttgaaag gatttgctgg ggatggaaaa ctatgttctg     3060

atatagatga atgtgagatg ggtgtcccag tgtgcccccc tgcctcctcc aagtgcatca     3120

acaccgaagg tggttatgtc tgccggtgct cagaaggcta ccaaggagat gggattcact     3180

gtcttgatat tgatgagtgc caactggggg agcacagctg tggagagaat gccagctgca     3240

caaatacaga gggaggctat acctgcatgt gtgctggacg cctgtctgaa ccaggactga     3300

tttgccctga ctctactcca ccccctcacc tcagggaaga tgaccaccac tattccgtaa     3360

gaaatagtga ctctgaatgt cccctgtccc acgatgggta ctgcctccat gatggtgtgt     3420

gcatgtatat tgaagcattg gacaagtatg catgcaactg tgttgttggc tacatcgggg     3480

agcgatgtca gtaccgagac ctgaagtggt gggaactgcg ccacgctggc cacgggcagc     3540

agcagaaggt catcgtggtg gctgtctgcg tggtggtgct tgtcatgctg ctcctcctga     3600

gcctgtgggg ggcccactac tacaggactc agaagctgct atcgaaaaac ccaaagaatc     3660

cttatgagga gtcgagcaga gatgtgagga gtcgcaggcc tgctgacact gaggatggga     3720

tgtcctcttg ccctcaacct tggtttgtgg ttataaaaga acaccaagac ctcaagaatg     3780

ggggtcaacc agtggctggt gaggatggcc aggcagcaga tgggtcaatg caaccaactt     3840

catggaggca ggagccccag ttatgtggaa tgggcacaga gcaaggctgc tggattccag     3900

tatccagtga taagggctcc tgtccccagg taatggagcg aagctttcat atgccctcct     3960

atgggacaca gacccttgaa gggggtgtcg agaagcccca ttctctccta tcagctaacc     4020

cattatggca acaaagggcc ctggacccac cacaccaaat ggagctgact cagtgaaaac     4080

tggaattaaa aggaaagtca agaagaatga actatgtcga tgcacagtat cttttctttc     4140

aaaagtagag caaaactata ggttttggtt ccacaatctc tacgactaat cacctactca     4200

atgcctggag acagatacgt agttgtgctt ttgtttgctc ttttaagcag tctcactgca     4260

gtcttatttc caagtaagag tactgggaga atcactaggt aacttattag aaacccaaat     4320

tgggacaaca gtgctttgta aattgtgttg tcttcagcag tcaatacaaa tagatttttg     4380

tttttgttgt tcctgcagcc ccagaagaaa ttaggggtta aagcagacag tcacactggt     4440

ttggtcagtt acaaagtaat ttctttgatc tggacagaac atttatatca gtttcatgaa     4500

atgattggaa tattacaata ccgttaagat acagtgtagg catttaactc ctcattggcg     4560

tggtccatgc tgatgatttt gcaaaatgag ttgtgatgaa tcaatgaaaa atgtaattta     4620

gaaactgatt tcttcagaat tagatggctt attttttaaa atatttgaat gaaaacattt     4680

tatttttaaa atattacaca ggaggcttcg gagtttctta gtcattactg tccttttccc     4740

ctacagaatt ttccctcttg gtgtgattgc acagaatttg tatgtatttt cagttacaag     4800

attgtaagta aattgcctga tttgttttca ttatagacaa cgatgaattt cttctaatta     4860

tttaaataaa atcaccaaaa acataaacat tttattgtat gcctgattaa gtagttaatt     4920

atagtctaag gcagtactag agttgaacca aaatgatttg tcaagcttgc tgatgtttct     4980

gtttttcgtt tttttttttt ttccggagag aggataggat ctcactctgt tatccaggct     5040

ggagtgtgca atggcacaat catagctcag tgcagcctca aactcctggg ctcaagcaat     5100

cctcctgcct cagcctcccg agtaactagg accacaggca caggccacca tgcctggcta     5160

aggtttttat ttttattttt tgtagacatg gggatcacac aatgttgccc aggctggtct     5220

tgaactcctg gcctcaagca aggtcgtgct ggtaattttg caaaatgaat tgtgattgac     5280

tttcagcctc ccaacgtatt agattatagg cattagccat ggtgcccagc cttgtaactt     5340

ttaaaaaaat tttttaatct acaactctgt agattaaaat ttcacatggt gttctaatta     5400

aatatttttc ttgcagccaa gatattgtta ctacagataa cacaacctga tatggtaact     5460

ttaaattttg ggggctttga atcattcagt ttatgcatta actagtccct ttgtttatct     5520

ttcatttctc aaccccttgt actttggtga taccagacat cagaataaaa agaaattgaa     5580

gtaaaaaaaa aaaaaaaaaa                                                 5600


<210>  2432
<211>  3136
<212>  DNA
<213>  homo sapiens

<400>  2432
gcgcagaact tggggagccg ccgccgccat ccgccgccgc agccagcttc cgccgccgca       60

ggaccggccc ctgccccagc ctccgcagcc gcggcgcgtc cacgcccgcc cgcgcccagg      120

gcgagtcggg gtcgccgcct gcacgcttct cagtgttccc cgcgccccgc atgtaacccg      180

gccaggcccc cgcaactgtg tcccctgcag ctccagcccc gggctgcacc cccccgcccc      240

gacaccagct ctccagcctg ctcgtccagg atggccgcgg ccaaggccga gatgcagctg      300

atgtccccgc tgcagatctc tgacccgttc ggatcctttc ctcactcgcc caccatggac      360

aactacccta agctggagga gatgatgctg ctgagcaacg gggctcccca gttcctcggc      420

gccgccgggg ccccagaggg cagcggcagc aacagcagca gcagcagcag cgggggcggt      480

ggaggcggcg ggggcggcag caacagcagc agcagcagca gcaccttcaa ccctcaggcg      540

gacacgggcg agcagcccta cgagcacctg accgcagagt cttttcctga catctctctg      600

aacaacgaga aggtgctggt ggagaccagt taccccagcc aaaccactcg actgcccccc      660

atcacctata ctggccgctt ttccctggag cctgcaccca acagtggcaa caccttgtgg      720

cccgagcccc tcttcagctt ggtcagtggc ctagtgagca tgaccaaccc accggcctcc      780

tcgtcctcag caccatctcc agcggcctcc tccgcctccg cctcccagag cccacccctg      840

agctgcgcag tgccatccaa cgacagcagt cccatttact cagcggcacc caccttcccc      900

acgccgaaca ctgacatttt ccctgagcca caaagccagg ccttcccggg ctcggcaggg      960

acagcgctcc agtacccgcc tcctgcctac cctgccgcca agggtggctt ccaggttccc     1020

atgatccccg actacctgtt tccacagcag cagggggatc tgggcctggg caccccagac     1080

cagaagccct tccagggcct ggagagccgc acccagcagc cttcgctaac ccctctgtct     1140

actattaagg cctttgccac tcagtcgggc tcccaggacc tgaaggccct caataccagc     1200

taccagtccc agctcatcaa acccagccgc atgcgcaagt accccaaccg gcccagcaag     1260

acgccccccc acgaacgccc ttacgcttgc ccagtggagt cctgtgatcg ccgcttctcc     1320

cgctccgacg agctcacccg ccacatccgc atccacacag gccagaagcc cttccagtgc     1380

cgcatctgca tgcgcaactt cagccgcagc gaccacctca ccacccacat ccgcacccac     1440

acaggcgaaa agcccttcgc ctgcgacatc tgtggaagaa agtttgccag gagcgatgaa     1500

cgcaagaggc ataccaagat ccacttgcgg cagaaggaca agaaagcaga caaaagtgtt     1560

gtggcctctt cggccacctc ctctctctct tcctacccgt ccccggttgc tacctcttac     1620

ccgtccccgg ttactacctc ttatccatcc ccggccacca cctcataccc atcccctgtg     1680

cccacctcct tctcctctcc cggctcctcg acctacccat cccctgtgca cagtggcttc     1740

ccctccccgt cggtggccac cacgtactcc tctgttcccc ctgctttccc ggcccaggtc     1800

agcagcttcc cttcctcagc tgtcaccaac tccttcagcg cctccacagg gctttcggac     1860

atgacagcaa ccttttctcc caggacaatt gaaatttgct aaagggaaag gggaaagaaa     1920

gggaaaaggg agaaaaagaa acacaagaga cttaaaggac aggaggagga gatggccata     1980

ggagaggagg gttcctctta ggtcagatgg aggttctcag agccaagtcc tccctctcta     2040

ctggagtgga aggtctattg gccaacaatc ctttctgccc acttcccctt ccccaattac     2100

tattcccttt gacttcagct gcctgaaaca gccatgtcca agttcttcac ctctatccaa     2160

agaacttgat ttgcatggat tttggataaa tcatttcagt atcatctcca tcatatgcct     2220

gaccccttgc tcccttcaat gctagaaaat cgagttggca aaatggggtt tgggcccctc     2280

agagccctgc cctgcaccct tgtacagtgt ctgtgccatg gatttcgttt ttcttggggt     2340

actcttgatg tgaagataat ttgcatattc tattgtatta tttggagtta ggtcctcact     2400

tgggggaaaa aaaaaaaaga aaagccaagc aaaccaatgg tgatcctcta ttttgtgatg     2460

atgctgtgac aataagtttg aacctttttt tttgaaacag cagtcccagt attctcagag     2520

catgtgtcag agtgttgttc cgttaacctt tttgtaaata ctgcttgacc gtactctcac     2580

atgtggcaaa atatggtttg gtttttcttt tttttttttt ttgaaagtgt tttttcttcg     2640

tccttttggt ttaaaaagtt tcacgtcttg gtgccttttg tgtgatgcgc cttgctgatg     2700

gcttgacatg tgcaattgtg agggacatgc tcacctctag ccttaagggg ggcagggagt     2760

gatgatttgg gggaggcttt gggagcaaaa taaggaagag ggctgagctg agcttcggtt     2820

ctccagaatg taagaaaaca aaatctaaaa caaaatctga actctcaaaa gtctattttt     2880

ttaactgaaa atgtaaattt ataaatatat tcaggagttg gaatgttgta gttacctact     2940

gagtaggcgg cgatttttgt atgttatgaa catgcagttc attattttgt ggttctattt     3000

tactttgtac ttgtgtttgc ttaaacaaag tgactgtttg gcttataaac acattgaatg     3060

cgctttattg cccatgggat atgtggtgta tatccttcca aaaaattaaa acgaaaataa     3120

agtagctgcg attggg                                                     3136


<210>  2433
<211>  3063
<212>  DNA
<213>  homo sapiens

<400>  2433
ccgaggggcg gtccctgggc tcccgctcgc cgccgctgcc gctcctcgtt ctgctcctca       60

ctccccagcg gctggaggcc ggtaccggcg ggcaggaggc gcccgaggat gtgctgctgg      120

ccgctgctcc tgctgtgggg gctgctcccc gggacggcgg cggggggctc gggccgaacc      180

tatccgcacc ggaccctcct ggactcggag ggcaagtact ggctgggctg gagccagcgg      240

ggcagccaga tcgccttccg cctccaggtg cgcactgcag gctacgtggg cttcggcttc      300

tcgcccaccg gggccatggc gtccgccgac atcgtcgtgg gcggggtggc ccacgggcgg      360

ccctacctcc aggattattt tacaaatgca aatagagagt tgaaaaaaga tgctcagcaa      420

gattaccatc tagaatatgc catggaaaat agcacacaca caataattga atttaccaga      480

gagctgcata catgtgacat aaatgacaag agtataacgg atagcactgt gagagtgatc      540

tgggcctacc accatgaaga tgcaggagaa gctggtccca agtaccatga ctccaatagg      600

ggcaccaaga gtttgcggtt attgaatcct gagaaaacta gtgtgctatc tacagcctta      660

ccatactttg atctggtaaa tcaggacgtc cccatcccaa acaaagatac aacatattgg      720

tgccaaatgt ttaagattcc tgtgttccaa gaaaagcatc atgtaataaa ggttgagcca      780

gtgatacaga gaggccatga gagtctggtg caccacatcc tgctctatca gtgcagcaac      840

aactttaacg acagcgttct ggagtccggc cacgagtgct atcaccccaa catgcccgat      900

gcattcctca cctgtgaaac tgtgattttt gcctgggcta ttggtggaga gggcttttct      960

tatccacctc atgttggatt atcccttggc actccattag atccgcatta tgtgctccta     1020

gaagtccatt atgataatcc cacttatgag gaaggcttaa tagataattc tggactgagg     1080

ttattttaca caatggatat aaggaaatat gatgctgggg tgattgaggc tggcctctgg     1140

gtgagcctct tccataccat ccctccaggg atgcctgagt tccagtctga gggtcactgc     1200

actttggagt gcctggaaga ggctctggaa gccgaaaagc caagtggaat tcatgtgttt     1260

gctgttcttc tccatgctca cctggctggc agaggcatca ggctgcgtca ttttcgaaaa     1320

gggaaggaaa tgaaattact tgcctatgat gatgattttg acttcaattt ccaggagttt     1380

cagtatctaa aggaagaaca aacaatctta ccaggagata acctaattac tgagtgtcgc     1440

tacaacacga aagatagagc tgagatgact tggggaggac taagcaccag gagtgaaatg     1500

tgtctctcat accttcttta ttacccaaga attaatctta ctcgatgtgc aagtattcca     1560

gacattatgg aacaacttca gttcattggg gttaaggaga tctacagacc agtcacgacc     1620

tggcctttca ttatcaaaag tcccaagcaa tataaaaacc tttctttcat ggatgctatg     1680

aataagttta aatggactaa aaaggaaggt ctctccttca acaagctggt cctcagcctg     1740

ccagtgaatg tgagatgttc caagacagac aatgctgagt ggtcgattca aggaatgaca     1800

gcattacctc cagatataga aagaccctat aaagcagaac ctttggtgtg tggcacgtct     1860

tcttcctctt ccctgcacag agatttctcc atcaacttgc ttgtttgcct tctgctactc     1920

agctgcacgc tgagcaccaa gagcttgtga tcaaaattct gttggacttg acaatgtttt     1980

ctatgatctg aacctgtcat ttgaagtaca ggttaaagac tgtgtccact ttgggcatga     2040

agagtgtgga gacttttctt ccccattttc cctccctcct ttttcctttc catgttacat     2100

gagagacatc aatcaggttc tcttctcttt cttagaaata tctgatgtta tatatacatg     2160

gtcaataaaa taaaactggc ctgacttaag ataaccattt taaaaaattg ggctgtcatg     2220

tgggaataaa agaattcttt ctttcctact acattctgtt ttatttaaat actcattgtt     2280

gctatttcac tttttgactt gacttttata tttctttaaa aaattccttc cttttaaaaa     2340

atataaaagg gactactgtt cattccagtt ttcttcttct ttgttgttct tctagtgtga     2400

cttttcaagt gtaacagcca ttcttcctga ctttaatatt gtccagttct ggtcttttct     2460

gtgaattacc actgggcccc ttacctcaat gctttttgtt gatgcccact ctggttccct     2520

tgtttatctg agtctgttgg taccccaaat gaccccacac ccatcttaaa gtactttttt     2580

tcaccttccc tgtttagtac tggccagatg agttttttct agagctctgt cactatctga     2640

aaagaaagag gctatgggaa acatagaaat ggtatgtatt aataactgat cataggctga     2700

ggagaaaaaa tgtagctggc tgcaaaccca gtgctgtgag gtgacttata tgaggttcca     2760

gatcaaagac aggccgtgtg agccagtcca ggagggtgta agttctgaat ggttccttgc     2820

tgactttggg tgacacatgt accacatact ggctcagttt aagtcatggt tctattgtag     2880

atttattttt atattagtta ataaatgact ttaaattgtc accaattgaa aatcttgtca     2940

ctcttttggt tttctttata tagctcagcc aaatcttgtt ttatgtcctg tcctcatctc     3000

ttaagctaaa tctgtttgga tcatattaat aaactaaatg aaattacaaa aaaaaaaaaa     3060

aaa                                                                   3063


<210>  2434
<211>  1050
<212>  DNA
<213>  homo sapiens

<400>  2434
actgctggct gaaggctgcg ctcaggcccg tggatctcat cgaagatggc ggcgcgatct       60

gtgtcgggca ttaccagaag agtcttcatg tggacagtct cagggacacc atgtagagaa      120

ttttggtctc gattcagaaa agagaaagag ccagtggttg ttgagacagt agaagagaaa      180

aaggaaccta tcctagtgtg tccaccttta cgaagccgag catacacacc acctgaagat      240

ctccagagtc gtttggaatc ttacgttaaa gaagtttttg gttcatctct tcctagtaat      300

tggcaagaca tctccctgga agatagtcgt ctaaagttca atcttctggc tcatttagct      360

gatgacttgg gtcatgtagt ccctaactcc agactccacc agatgtgcag ggttagagat      420

gttcttgatt tctataatgt ccctattcaa gatagatcta aatttgatga actcagtgcc      480

agtaatctgc cccccaattt gaaaatcact tggagttact aagcaattcg gaagagaaac      540

acattgaaat cactgtcttt ccctgagcaa gggggctgct cattagatct tttgatactt      600

taccatgtga aatactacca gaactgttct ctaaacccac tttttctgta gaggaatgta      660

tcatcttttt ttttctcata ttacaaatgg acaaataacg gactttctat tttcatattt      720

gctgaaacca ttttttaaat gaaattaggt cattatttat gaaaagtttt gagagggcac      780

tgtcaacttg ggtttaagac aggaggacat tgcaagttca cacctttcat aagcataaag      840

tagttgcaag aaagtatttt catcctgtta ggattcatat ctaagataga gttatgcatt      900

gcacatacac aaataaactt ttattagata gatacctata aaagaaacat aaaagtatgt      960

tgtgtattac tgacagttct agattaattt cttttagaat taaagtagat ttgttaaagt     1020

gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                                      1050


<210>  2435
<211>  1050
<212>  DNA
<213>  homo sapiens

<400>  2435
actgctggct gaaggctgcg ctcaggcccg tggatctcat cgaagatggc ggcgcgatct       60

gtgtcgggca ttaccagaag agtcttcatg tggacagtct cagggacacc atgtagagaa      120

ttttggtctc gattcagaaa agagaaagag ccagtggttg ttgagacagt agaagagaaa      180

aaggaaccta tcctagtgtg tccaccttta cgaagccgag catacacacc acctgaagat      240

ctccagagtc gtttggaatc ttacgttaaa gaagtttttg gttcatctct tcctagtaat      300

tggcaagaca tctccctgga agatagtcgt ctaaagttca atcttctggc tcatttagct      360

gatgacttgg gtcatgtagt ccctaactcc agactccacc agatgtgcag ggttagagat      420

gttcttgatt tctataatgt ccctattcaa gatagatcta aatttgatga actcagtgcc      480

agtaatctgc cccccaattt gaaaatcact tggagttact aagcaattcg gaagagaaac      540

acattgaaat cactgtcttt ccctgagcaa gggggctgct cattagatct tttgatactt      600

taccatgtga aatactacca gaactgttct ctaaacccac tttttctgta gaggaatgta      660

tcatcttttt ttttctcata ttacaaatgg acaaataacg gactttctat tttcatattt      720

gctgaaacca ttttttaaat gaaattaggt cattatttat gaaaagtttt gagagggcac      780

tgtcaacttg ggtttaagac aggaggacat tgcaagttca cacctttcat aagcataaag      840

tagttgcaag aaagtatttt catcctgtta ggattcatat ctaagataga gttatgcatt      900

gcacatacac aaataaactt ttattagata gatacctata aaagaaacat aaaagtatgt      960

tgtgtattac tgacagttct agattaattt cttttagaat taaagtagat ttgttaaagt     1020

gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                                      1050


<210>  2436
<211>  3352
<212>  DNA
<213>  homo sapiens

<400>  2436
accgcctccc aggccaggcg agcaggcggg tggctggggc gcctccacct cctcttccta       60

aagcggcgag gcgcagagga gcggcatcac tcgagcccag gtcccagcca ccaccactca      120

cagcgctcgg cgttcaggaa gaggagcagc agcggaggcg gctgcttcag cggcgggcgg      180

gcgccagaaa ggccccgatc gaaaagcctg ggagggccgc cgaactaccc ccggagggag      240

gagccagtcc gaacccaagg cgccaccgcc gcagaagcgg agcgaggcag cattcgcctc      300

catggcccac tcgccggtgg ctgtccaagt gcctgggatg cagaataaca tagctgatcc      360

agaagaactg ttcacaaaat tagagcgcat tgggaaaggc tcatttgggg aagttttcaa      420

aggaattgat aaccgtaccc agcaagtcgt tgctattaaa atcatagacc ttgaggaagc      480

cgaagatgaa atagaagaca ttcagcaaga aataactgtc ttgagtcaat gtgacagctc      540

atatgtaaca aaatactatg ggtcatattt aaaggggtct aaattatgga taataatgga      600

atacctgggc ggtggttcag cactggatct tcttcgagct ggtccatttg atgagttcca      660

gattgctacc atgctaaagg aaattttaaa aggtctggac tatctgcatt cagaaaagaa      720

aattcaccga gacataaaag ctgccaatgt cttgctctca gaacaaggag atgttaaact      780

tgctgatttt ggagttgctg gtcagctgac agatacacag attaaaagaa atacctttgt      840

gggaactcca ttttggatgg ctcctgaagt tattcaacag tcagcttatg actcaaaagc      900

tgacatttgg tcattgggaa ttactgctat tgaactagcc aagggagagc cacctaactc      960

cgatatgcat ccaatgagag ttctgtttct tattcccaaa aacaatcctc caactcttgt     1020

tggagacttt actaagtctt ttaaggagtt tattgatgct tgcctgaaca aagatccatc     1080

atttcgtcct acagcaaaag aacttctgaa acacaaattc attgtaaaaa attcaaagaa     1140

gacttcttat ctgactgaac tgatagatcg ttttaagaga tggaaggcag aaggacacag     1200

tgatgatgaa tctgattccg agggctctga ttcggaatct accagcaggg aaaacaatac     1260

tcatcctgaa tggagcttta ccaccgtacg aaagaagcct gatccaaaga aagtacagaa     1320

tggggcagag caagatcttg tgcaaaccct gagttgtttg tctatgataa tcacacctgc     1380

atttgctgaa cttaaacagc aggacgagaa taacgctagc aggaatcagg cgattgaaga     1440

actcgagaaa agtattgctg tggctgaagc cgcctgtccc ggcatcacag ataaaatggt     1500

gaagaaacta attgaaaaat ttcaaaagtg ttcagcagac gaatccccct aagaaactta     1560

ttattggctt ctgtttcata tggacccaga gagccccacc aaacctacgt caagattaac     1620

aatgcttaac ccatgagctc catgtgcctt ttggatcttt gcaacactga agatttggaa     1680

gaagctatta aactattttg tgatggcgtt tatcatttta tattttgaaa ggattatttt     1740

gtaaggaata acttttaata ctatagtttc acctgtattc tagtaaatgt tgagacaccg     1800

ttttgctttt aagtatccct atttcttaag ttacgaggat gaataccttt cacattttga     1860

tctttagttg actctacagt catgaaacat acaggtcttt caaagtcatt ctcaatattc     1920

agcttttgta aattatcaag cttcaaaaag cttttttttt taaaaaaaaa catgcatatt     1980

ctaaaaatga ctattggtgg ggaggtgtaa ataagtcata ccttcttaaa acagaaaatt     2040

taagtaaagt cttttaaatg aaacctgtaa aagtattgac tcttctacca agttggtatg     2100

atattccagg cagctcaatg attatcacat ttgagaccct gtgtttgaag catttacagg     2160

caatgtacag caacagaggt acctcttggt gtatagtatt tacattctct tttaggtaga     2220

agaggcaatt ttacccttat ttcacatggt tagaaattta aagcaagatc atttacccaa     2280

ggataggtgt ttggtaatgt tgaaggagtt agtctggctt catgttttac atcttcaact     2340

aaaatcccat actatctgct tggatttgga gagccaaaaa ataaagctga ttgtcatgtg     2400

attaaatatc tgatcaacag gtatgaatat aacttaaatc agcatatttt tgccatggta     2460

ataaattgtc ctataaacta tttatatatt tttgttcttc ataattatca ctaataagca     2520

tcagtttgtt gtttttaaaa ggatatttaa gtgagcattt tctagttcat atgaaaataa     2580

ccatagtaca ggatgatttc tgtccacaca aaggttaaat tagattgcac agttaatttt     2640

cacttatatt tatggtacta ttatgtgggt gatgcctttt tcttttaagc ccagtacata     2700

tattatgcct gcctaagttc tgaactgggg ctgtatttca gtagttgtag aattattgat     2760

atttagtttt gatagctaat gtttaattgt ttggatctgc acagtttggt ttttgcacaa     2820

aagtcattta aaaaaatctg agtaattgtc aaatattaaa agaaagatat tcttcctgta     2880

aggaatacag tttttagtca aagtggccat tacatcctct ttttaattta cataatacag     2940

atacttgaga aagttgttgt ggtgttgtat gccaagaaaa ttctttttat tggtgcctat     3000

attgtaacaa ttatttttaa tgcattgtat tttgaagtaa cggttcagtt aaatttttca     3060

cctgctgtgt aactgaaaca caattacagt ttataatcat ctgtagaagt ctggagataa     3120

ttttgcaact catgttatgg gttaaatgaa tatttttgta aaagtaaaag caacaaattt     3180

ataaattgat tatttgaaac tttacaacac aattgcatcc caaatacaaa ttgtattgct     3240

tattcattat agctattcgt cctgtaatct gtttctaggt gaagcatact ccagtgtttt     3300

aggggttttg aaaataaata tttaaatttc acagtcaaaa aaaaaaaaaa aa             3352


<210>  2437
<211>  4803
<212>  DNA
<213>  homo sapiens

<400>  2437
agttcagaca gaaaacctgg cgcgcgcgcg cgcacacaca cacgcctccc ctggcgtcgc       60

cgcccggccg ggtccctgcc cttagggacc agagcggcga ccgctgcacc ccgcaccgcc      120

tgctggagga gcccccggag ccggggccga gccgccggcg tccccgagtg cgccccctgt      180

gcgtgccgcc gcgctgttgc tcgcagtgtg ctggcgccga gctcggtgga cacgcgcgca      240

gtcagagctg cctctcgccc tcgctagctg ggctcgcagc ctcttcctcc ctccctggct      300

cctggctttt tgtttaaagc aacacccacc ctccatccag gctttttttc tttctttctt      360

tattggtagc ggccaaaaag agttgattgc tattgggatc cgctgagtaa agacacgggc      420

aggggtgcgc ggaggtgaga aaactgaaga cctggaagat ttttttttcc ttcaaaaacc      480

cgtttccatc cagtcttcag ccagtccagt ctactttaat cctcaccagg acaatggatt      540

aagtttctct tccctggacc agaagtcggg ttcggacttg gggcaaaatg aaggaaaagg      600

ccatgatcaa gaccgctaag atgcagggga acgtgatgga gctggtgggg agtaaccctc      660

cgcagaggaa ttggaaagga atagcaattg cactgcttgt cattctggtc atctgctcct      720

tgatcgtcac ctcggtcata cttctgacac cagcggaaga taatagtctg tctcaaaaga      780

agaaggtcac tgtagaagat ctcttcagtg aagacttcaa aattcatgac cccgaggcta      840

agtggataag tgatacagaa ttcatctaca gagaacagaa aggaacagtg agactgtgga      900

atgttgaaac aaatacttct actgtcttaa tagaaggcaa aaaaattgaa tcattaagag      960

ccatcagata tgaaatatct ccagatagag agtatgcact tttttcatac aatgtggaac     1020

ccatatatca acactcgtat actggatatt acgtcctgag caaaattcct catggggatc     1080

ctcaaagtct ggacccacca gaagtcagca atgcaaaact tcagtatgca ggatggggcc     1140

ctaaaggcca acagctgata tttatttttg aaaacaatat ctactactgt gcacatgtcg     1200

ggaaacaggc catccgtgtg gtctccactg gcaaggaagg tgtgatttac aatggcctca     1260

gtgactggct gtatgaagag gagattttga agacacacat cgcacactgg tggtctccgg     1320

atggcacgag actcgcctac gccgccatca atgattcccg tgtccccatc atggagctcc     1380

caacttacac cggctccatc taccccaccg tgaagcccta ccactatccc aaggctggaa     1440

gtgagaaccc cagcatttcc ctacacgtta ttggcttaaa tggacccacc catgatctgg     1500

agatgatgcc gcctgatgat ccacggatga gggagtacta catcaccatg gtgaagtggg     1560

ccaccagcac caaggtcgcc gtgacctggc tgaaccgggc gcagaacgtg tccatcctca     1620

ccctctgcga cgccaccacg ggggtctgca cgaagaaaca cgaggatgaa agtgaggcct     1680

ggctccacag acagaatgaa gaacctgtgt tctccaagga tggccgaaag tttttcttca     1740

tcagagccat cccccaggga ggacgaggga aattctatca catcacggtg tcctcgtccc     1800

agcccaacag cagcaacgac aacatccagt ccatcacctc cggggactgg gacgtgacca     1860

agatcctagc ctacgatgag aaggggaata agatctactt cctgagcacg gaggacctgc     1920

ctcggagacg acaactctac agtgccaaca cggtgggcaa cttcaacagg cagtgcctct     1980

cctgtgacct ggttgagaac tgcacctact tcagcgcttc cttcagccat agcatggact     2040

tcttcctgct caagtgcgaa ggtcctggtg ttcctatggt gacggtgcac aacacaacag     2100

ataagaaaaa aatgtttgac ctagaaacaa atgaacatgt caagaaggcc ataaatgacc     2160

gacagatgcc taaagtggaa tacagggaca ttgagattga tgattacaac ctgcccatgc     2220

agatactgaa gccagcaacc ttcaccgaca ccacccacta ccctctgctc ctggtggtgg     2280

atggcacccc aggcagccag agtgtggctg agaagttcga ggtgagctgg gagacggtga     2340

tggtgagcag ccacggcgcg gtggtggtaa agtgtgacgg ccgtggcagc ggcttccaag     2400

ggaccaagct cctgcacgaa gtgaggcggc ggctgggctt gctggaggag aaggaccaga     2460

tggaggccgt gcggacgatg ctgaaggagc agtacattga caggacgcgc gtggccgtgt     2520

ttgggaagga ttacggtggc tacctgagca cctacatcct cccagcaaag ggagaaaatc     2580

aaggccagac attcacctgc ggctctgctc tctctccaat aacagacttc aaactctatg     2640

cctctgcgtt ttccgagagg tacttgggcc tccatggact tgacaacaga gcatacgaga     2700

tgaccaaggt agcccatcga gtctccgcgc tggaagaaca gcagttcctg atcattcatc     2760

ccactgccga tgaaaaaatt catttccagc acacagcaga actcattaca caactaatta     2820

ggggaaaggc taattacagc ttacagattt acccggacga aagccattac tttaccagct     2880

ccagcctcaa acagcatctg taccggtcca tcatcaactt cttcgtggaa tgcttcagga     2940

tccaggacaa actgctgaca gtcacagcga aagaggacga ggaggaggac taagctcagg     3000

tcgctctaag cacaaacgtg gctctttcta caaccagatg caaccgaggg atttccctgc     3060

cctccctctt ccctcggagg ggcggggcgg ggcggggccg ggtgttccat agcatgtgtg     3120

tctcggatgc ggaaggcagt tttgcttggg aaacaagctc cttccccggg gtcatcactc     3180

acggcctcca tggcaccagg gacaacgctg tccccgcagc agcgcctcct cccggcgccc     3240

gagagaccgg cacgccacgg cccctccccc aaggaacaga gcaaaggatg gtggccgcag     3300

gccccacgcg agcccacagg acaccggccc ctagattcca gccaccaagc ggaagcatga     3360

gacccgccca cactagcctc tgtgttcccg ttagggacat cacaccctgt ctcacgtcgc     3420

agtgccatgg acgcagcagt tacagcacca ttgttttagc agtgcgtgtt catatatggg     3480

cttgctactt cctgtaatga ggacgttcaa catggtgagg ggctacaaga aaacgctttt     3540

ctgtacagag tcttactgta gctacgctaa tggttaacct gatagaatta actcgtattt     3600

ttctatggtt ttaacctgat gctccactgt ctccgtcatg gggttgtttt gctgtttggg     3660

gttgggcctt gtttcccttt cctttctcca gtccacgtgt agactttgcg cttgatgaag     3720

aagcagatcg gaagtaactg ctccctcctc aaggttgtct tcagacgtct tggggacgtt     3780

cctaaacact gagggggaag acagccaata gcacccatta aaagaaatac ctaaataaaa     3840

cctctctccc actcagctat gctagggctt ggctgtaggt gtgcactgtc tatttacatc     3900

cgtccttaca accatccttg tcctccttgg taccgtatca agctctttcc catgacattt     3960

ggtttaaaaa aaaaaaaaaa aaaaaaaaaa aaacagaaaa aagacaaagc gtcaactcca     4020

cccacaggcc cgctgtgtgt gctcgggcca cgggagtcct gagggttctg tgggcctgcg     4080

cgcatccctc tcccatcgtg ggggtggctc cgtgaccttc ctgccacgag caggaggttg     4140

atgatgtgct acgttagcct tgtaagatac acccccacca aatgtgcagc cggtgttccc     4200

agtgtatatt tcattctctt gtatataaag gaagcaatgt gtgtcaggcc tctgtgcagt     4260

caacccagcc tcctcccgcc agtgctaacc ccgtgttgag cctgcatgct gacactgtgg     4320

ccgatctgga ctctagaagt gctagtttga aatatatcca ttactgtcat ttccttttga     4380

gcttgtggac aagctgaatg tcaggactga cttcgccagc tcccagccct gcgggggtgt     4440

ccttggcatc ccatcagcag aggagatgcg tccctgttgc attttggcgt ttggggcttt     4500

gggtttatcc acatgagctc tgaacgtccg ttatagttag ggtgattgga aggtctccat     4560

cactgggtgt tttaaaggtg attcaccacc atttgtgaaa ggaccaacgt gctgataaac     4620

aggaccgatc cgagtgctac atgactgtgc gtttgctatt tcaatgggcc tgaacgacta     4680

caaagccagc taggtctgga aggggaagcc agctctggcc acgacatctg gtcggaggga     4740

agtggggatg tggcatggta gcgtctgttc atccatggaa taaaacatta ttttaccact     4800

cgg                                                                   4803


<210>  2438
<211>  2949
<212>  DNA
<213>  homo sapiens

<400>  2438
gagctcgccg tcgctccgtc atagagttcg ccccacccca tcccctcctt tctggactcg       60

gagctcagtt cacgcagtaa caaatgaagt gcgcgctgcg acacctccca gcccaccgaa      120

ctccgccgcc atttcctcgc ttggcctaac ggttcggcca atcccagcgc gcatcaagaa      180

ggactgaggc tccgccaatc ggaggccgcc gatttcgacc cttcgcctcg gcccggccca      240

atccaggccc cggccccgcc gcccccggcc cgcccccgcg gtgccctctc tcctccctct      300

ttgtgcgtct cgcgccgccg ccgcccgccg cgtgagagga cgggctccgc gcgctccggc      360

agcgcattcg ggtcccctcc ccccgggagg cttgcgaagg agaagccgcc gcagaggaaa      420

agcaggtgcc ggtgcctgtc cccgggggcg ccatggcgac cggagcgaac gccacgccgt      480

tggacttccc aagtaagaag cggaagagga gccgctggaa ccaagacaca atggaacaga      540

agacagtgat tccaggaatg cctacagtta ttccccctgg acttactcga gaacaagaaa      600

gagcttatat agtgcaactg cagatagaag acctgactcg taaactgcgc acaggagacc      660

tgggcatccc ccctaaccct gaggacaggt ccccttcccc tgagcccatc tacaatagcg      720

aggggaagcg gcttaacacc cgagagttcc gcacccgcaa aaagctggaa gaggagcggc      780

acaacctcat cacagagatg gttgcactca atccggattt caagccacct gcagattaca      840

aacctccagc aacacgtgtg agtgataaag tcatgattcc acaagatgag tacccagaaa      900

tcaactttgt ggggctgctc atcgggccca gagggaacac cctgaagaac atagagaagg      960

agtgcaatgc caagattatg atccggggga aagggtctgt gaaagaaggg aaggttgggc     1020

gcaaagatgg ccagatgttg ccaggagaag atgagccact tcatgccctg gttactgcca     1080

atacaatgga gaacgtcaaa aaggcagtgg aacagataag aaacatcctg aagcagggta     1140

tcgagactcc agaggaccag aatgatctac ggaagatgca gcttcgggag ttggctcgct     1200

taaatgggac ccttcgggaa gacgataaca ggatcttaag accctggcag agctcagaga     1260

cccgcagcat taccaacacc acagtgtgta ccaagtgtgg aggggctggc cacattgctt     1320

cagactgtaa attccaaagg cctggtgatc ctcagtcagc tcaggataaa gcacggatgg     1380

ataaagaata tttgtccctc atggctgaac tgggtgaagc acctgtccca gcatctgtgg     1440

gctccacctc tgggcctgcc accacacccc tggccagcgc acctcgtcct gctgctcccg     1500

ccaacaaccc acctccaccg tctctcatgt ctaccaccca gagccgccca ccctggatga     1560

attctggccc ttcagagagt cggccctacc acggcatgca tggaggtggt cctggtgggc     1620

ccggaggtgg cccccacagc ttcccacacc cattacccag cctgacaggt gggcatggtg     1680

gacatcccat gcagcacaac cccaatggac ccccaccccc ttggatgcag ccaccaccac     1740

caccgatgaa ccagggcccc caccctcctg ggcaccatgg ccctcctcca atggatcagt     1800

acctgggaag tacgcctgtg ggctctgggg tctatcgcct gcatcaagga aaaggtatga     1860

tgccgccacc acctatgggc atgatgccgc cgccgccgcc gcctcccagt gggcagcccc     1920

caccccctcc ctctggtcct cttcccccat ggcaacaaca gcagcagcag cctccgccac     1980

cccctccgcc cagcagcagt atggcttcca gtaccccctt gccatggcag caaagatccc     2040

tccccgcggc ggcgatggcc cgagccatga gagtgaggac tttccgcgcc cattggtgac     2100

ccttccaggc agacagcctc agcaacgccc ctggtggaca ggatggttcg gcaaagcagc     2160

ctgagttatt tttgtggacg gaatcggaac acgctggctc catatcgtga aatttttatt     2220

aatttttttc tttttccttt gttacttctt tatcttttcc tttcttcaga ctccgtccaa     2280

ggagatgctc tccccggtct tctgctgcaa tttagattcc tttcccttct ctccagttct     2340

ccttccctta ccaaggagag gggagcaaat ggttttgggc aagggctttg gccattcatg     2400

tcaagctggt tgtgggtttt tcaaggtgcc atagccaccc ccaaagatgt ttgtttaaag     2460

cgtggggttt tttaatctct gccacccttg tcaagggagt cttgtaaagt tgccgagggt     2520

aggttcatct ccaggtttcg ggattcccat ccgtcctggc gatcctgcca gcagtgggtg     2580

ggcagcctga gctccctcgg gctcgcctgc cagcctggag ttcttcctgt gctccttgat     2640

cacctgagct gcctcagatt ccatttggtc ctctccttcc tggaaggctt ccttttatgt     2700

tttgttttaa tcccaaatgt ctgaatgttt tgcagtgtgt aggggtttga gccccttgtt     2760

cattctcctt cctttttcct cccgcttccc tctccatgaa gtgattctgt tgacaataat     2820

gtatactgcg cgttctcttc actggtttat ctgcagaaat ttctctgggc ttttttcggt     2880

gttagattca acactgcgct aaagcgggga tgttccattg aataaaagag cagtgtggtt     2940

ttctgggtc                                                             2949


<210>  2439
<211>  951
<212>  DNA
<213>  homo sapiens

<400>  2439
cccgccccgc cccgcccggc tgctccatgg cgctgtgcga ggccgcgggc tgcgggagtg       60

ccctgctctg gcctcgcttg ttgctcttcg gggactccat cacccagttt tccttccagc      120

agggtggatg gggagcatcg ctggctgaca ggctggtcag aaaatgtgat gttctgaatc      180

gtggattttc aggttacaat accaggtggg ccaaaattat ccttccaaga ttaatcagga      240

aaggaaacag tttggacatc ccagtagcag ttacaatttt ctttggggcc aatgacagtg      300

cactaaaaga tgagaatccc aagcagcaca ttcccctgga ggagtacgct gcgaacctaa      360

agagcatggt gcagtacctg aagtccgtgg acatccctga gaatcgagtc attctcatca      420

cgccgacccc actttgtgaa acagcctggg aagaacagtg catcatacaa ggttgcaaac      480

taaatcgcct gaactctgtt gttggtgaat atgccaatgc gtgtttacaa gtggcccaag      540

actgtgggac tgacgtactt gacctgtgga ccctgatgca ggacagccag gacttctcat      600

cttatttatc agatggacta catttgtctc caaaggggaa tgaatttttg ttctcgcatc      660

tctggccttt gatagagaaa aaggtctctt ctctaccttt gctgcttcct tactggcggg      720

atgtagcaga agcaaaacct gaattaagtc tgctgggaga tggagaccat tagccaatca      780

caggagaccc aaatctgctt gttatctaca gaactcaaag ttgtcaatac gtagaggtac      840

gcttttttcc tcaggcttaa acctttgcca ctgatattaa taataaaagt attagatgat      900

ttttcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a               951


<210>  2440
<211>  1252
<212>  DNA
<213>  homo sapiens

<400>  2440
gatctggggt gctgccagga aaaagcaaat tctggaagtt aatggttttg agtgattttt       60

aaatccttgc tggcggagag gcccgcctct ccccggtatc agcgcttcct cattctttga      120

atccgcggct ccgcggtctt cggcgtcaga ccagccggag gaagcctgtt tgcaatttaa      180

gcgggctgtg aacgcccagg gccggcgggg gcagggccga ggcgggccat tttgaataaa      240

gaggcgtgcc ttccaggcag gctctataag tgaccgccgc ggcgagcgtg cgcgcgttgc      300

aggtcactgt agcgggactt cttttggttt tctttctctt tggggcacct ctggactcac      360

tccccagcat gaaggcgctg agcccggtgc gcggctgcta cgaggcggtg tgctgcctgt      420

cggaacgcag tctggccatc gcccggggcc gagggaaggg cccggcagct gaggagccgc      480

tgagcttgct ggacgacatg aaccactgct actcccgcct gcgggaactg gtacccggag      540

tcccgagagg cactcagctt agccaggtgg aaatcctaca gcgcgtcatc gactacattc      600

tcgacctgca ggtagtcctg gccgagccag cccctggacc ccctgatggc ccccaccttc      660

ccatccagac agccgagctc actccggaac ttgtcatctc caacgacaaa aggagctttt      720

gccactgact cggccgtgtc ctgacacctc cagaacgcag gtgctggcgc ccgttctgcc      780

tgggaccccg ggaacctctc ctgccggaag ccggacggca gggatgggcc ccaacttcgc      840

cctgcccact tgacttcacc aaatcccttc ctggagacta aacctggtgc tcaggagcga      900

aggactgtga acttgtggcc tgaagagcca gagctagctc tggccaccag ctgggcgacg      960

tcaccctgct cccaccccac ccccaagttc taaggtctct tcagagcgtg gaggtgtgga     1020

aggagtggct gctctccaaa ctatgccaag gcggcggcag agctggtctt ctggtctcct     1080

tggagaaagg ttctgttgcc ctgatttatg aactctataa tagagtatat aggttttgta     1140

ccttttttac aggaaggtga ctttctgtaa caatgcgatg tatattaaac tttttataaa     1200

agttaacatt ttgcataata aacgattttt aaacacttga aaaaaaaaaa aa             1252


<210>  2441
<211>  4819
<212>  DNA
<213>  homo sapiens

<400>  2441
cgctgtctct ccccctcggc tcggagaggc ccttcggcct gagggagcct cgccgcccgt       60

ccccggcaca cgcgcagccc cggcctctcg gcctctgccg gagaaacagt tgggacccct      120

gattttagca ggatggccca atggaatcag ctacagcagc ttgacacacg gtacctggag      180

cagctccatc agctctacag tgacagcttc ccaatggagc tgcggcagtt tctggcccct      240

tggattgaga gtcaagattg ggcatatgcg gccagcaaag aatcacatgc cactttggtg      300

tttcataatc tcctgggaga gattgaccag cagtatagcc gcttcctgca agagtcgaat      360

gttctctatc agcacaatct acgaagaatc aagcagtttc ttcagagcag gtatcttgag      420

aagccaatgg agattgcccg gattgtggcc cggtgcctgt gggaagaatc acgccttcta      480

cagactgcag ccactgcggc ccagcaaggg ggccaggcca accaccccac agcagccgtg      540

gtgacggaga agcagcagat gctggagcag caccttcagg atgtccggaa gagagtgcag      600

gatctagaac agaaaatgaa agtggtagag aatctccagg atgactttga tttcaactat      660

aaaaccctca agagtcaagg agacatgcaa gatctgaatg gaaacaacca gtcagtgacc      720

aggcagaaga tgcagcagct ggaacagatg ctcactgcgc tggaccagat gcggagaagc      780

atcgtgagtg agctggcggg gcttttgtca gcgatggagt acgtgcagaa aactctcacg      840

gacgaggagc tggctgactg gaagaggcgg caacagattg cctgcattgg aggcccgccc      900

aacatctgcc tagatcggct agaaaactgg ataacgtcat tagcagaatc tcaacttcag      960

acccgtcaac aaattaagaa actggaggag ttgcagcaaa aagtttccta caaaggggac     1020

cccattgtac agcaccggcc gatgctggag gagagaatcg tggagctgtt tagaaactta     1080

atgaaaagtg cctttgtggt ggagcggcag ccctgcatgc ccatgcatcc tgaccggccc     1140

ctcgtcatca agaccggcgt ccagttcact actaaagtca ggttgctggt caaattccct     1200

gagttgaatt atcagcttaa aattaaagtg tgcattgaca aagactctgg ggacgttgca     1260

gctctcagag gatcccggaa atttaacatt ctgggcacaa acacaaaagt gatgaacatg     1320

gaagaatcca acaacggcag cctctctgca gaattcaaac acttgaccct gagggagcag     1380

agatgtggga atgggggccg agccaattgt gatgcttccc tgattgtgac tgaggagctg     1440

cacctgatca cctttgagac cgaggtgtat caccaaggcc tcaagattga cctagagacc     1500

cactccttgc cagttgtggt gatctccaac atctgtcaga tgccaaatgc ctgggcgtcc     1560

atcctgtggt acaacatgct gaccaacaat cccaagaatg taaacttttt taccaagccc     1620

ccaattggaa cctgggatca agtggccgag gtcctgagct ggcagttctc ctccaccacc     1680

aagcgaggac tgagcatcga gcagctgact acactggcag agaaactctt gggacctggt     1740

gtgaattatt cagggtgtca gatcacatgg gctaaatttt gcaaagaaaa catggctggc     1800

aagggcttct ccttctgggt ctggctggac aatatcattg accttgtgaa aaagtacatc     1860

ctggcccttt ggaacgaagg gtacatcatg ggctttatca gtaaggagcg ggagcgggcc     1920

atcttgagca ctaagcctcc aggcaccttc ctgctaagat tcagtgaaag cagcaaagaa     1980

ggaggcgtca ctttcacttg ggtggagaag gacatcagcg gtaagaccca gatccagtcc     2040

gtggaaccat acacaaagca gcagctgaac aacatgtcat ttgctgaaat catcatgggc     2100

tataagatca tggatgctac caatatcctg gtgtctccac tggtctatct ctatcctgac     2160

attcccaagg aggaggcatt cggaaagtat tgtcggccag agagccagga gcatcctgaa     2220

gctgacccag gtagcgctgc cccatacctg aagaccaagt ttatctgtgt gacaccattc     2280

attgatgcag tttggaaata atggtgaagg tgctgaaccc tcagcaggag ggcagtttga     2340

gtccctcacc tttgacatgg agttgacctc ggagtgcgct acctccccca tgtgaggagc     2400

tgagaacgga agctgcagaa agatacgact gaggcgccta cctgcattct gccacccctc     2460

acacagccaa accccagatc atctgaaact actaactttg tggttccaga ttttttttaa     2520

tctcctactt ctgctatctt tgagcaatct gggcactttt aaaaatagag aaatgagtga     2580

atgtgggtga tctgctttta tctaaatgca aataaggatg tgttctctga gacccatgat     2640

caggggatgt ggcggggggt ggctagaggg agaaaaagga aatgtcttgt gttgttttgt     2700

tcccctgccc tcctttctca gcagcttttt gttattgttg ttgttgttct tagacaagtg     2760

cctcctggtg cctgcggcat ccttctgcct gtttctgtaa gcaaatgcca caggccacct     2820

atagctacat actcctggca ttgcactttt taaccttgct gacatccaaa tagaagatag     2880

gactatctaa gccctaggtt tctttttaaa ttaagaaata ataacaatta aagggcaaaa     2940

aacactgtat cagcatagcc tttctgtatt taagaaactt aagcagccgg gcatggtggc     3000

tcacgcctgt aatcccagca ctttgggagg ccgaggcgga tcataaggtc aggagatcaa     3060

gaccatcctg gctaacacgg tgaaaccccg tctctactaa aagtacaaaa aattagctgg     3120

gtgtggtggt gggcgcctgt agtcccagct actcgggagg ctgaggcagg agaatcgctt     3180

gaacctgaga ggcggaggtt gcagtgagcc aaaattgcac cactgcacac tgcactccat     3240

cctgggcgac agtctgagac tctgtctcaa aaaaaaaaaa aaaaaaaaga aacttcagtt     3300

aacagcctcc ttggtgcttt aagcattcag cttccttcag gctggtaatt tatataatcc     3360

ctgaaacggg cttcaggtca aacccttaag acatctgaag ctgcaacctg gcctttggtg     3420

ttgaaatagg aaggtttaag gagaatctaa gcattttaga ctttttttta taaatagact     3480

tattttcctt tgtaatgtat tggcctttta gtgagtaagg ctgggcagag ggtgcttaca     3540

accttgactc cctttctccc tggacttgat ctgctgtttc agaggctagg ttgtttctgt     3600

gggtgcctta tcagggctgg gatacttctg attctggctt ccttcctgcc ccaccctccc     3660

gaccccagtc cccctgatcc tgctagaggc atgtctcctt gcgtgtctaa aggtccctca     3720

tcctgtttgt tttaggaatc ctggtctcag gacctcatgg aagaagaggg ggagagagtt     3780

acaggttgga catgatgcac actatggggc cccagcgacg tgtctggttg agctcaggga     3840

atatggttct tagccagttt cttggtgata tccagtggca cttgtaatgg cgtcttcatt     3900

cagttcatgc agggcaaagg cttactgata aacttgagtc tgccctcgta tgagggtgta     3960

tacctggcct ccctctgagg ctggtgactc ctccctgctg gggccccaca ggtgaggcag     4020

aacagctaga gggcctcccc gcctgcccgc cttggctggc tagctcgcct ctcctgtgcg     4080

tatgggaaca cctagcacgt gctggatggg ctgcctctga ctcagaggca tggccggatt     4140

tggcaactca aaaccacctt gcctcagctg atcagagttt ctgtggaatt ctgtttgtta     4200

aatcaaatta gctggtctct gaattaaggg ggagacgacc ttctctaaga tgaacagggt     4260

tcgccccagt cctcctgcct ggagacagtt gatgtgtcat gcagagctct tacttctcca     4320

gcaacactct tcagtacata ataagcttaa ctgataaaca gaatatttag aaaggtgaga     4380

cttgggctta ccattgggtt taaatcatag ggacctaggg cgagggttca gggcttctct     4440

ggagcagata ttgtcaagtt catggcctta ggtagcatgt atctggtctt aactctgatt     4500

gtagcaaaag ttctgagagg agctgagccc tgttgtggcc cattaaagaa cagggtcctc     4560

aggccctgcc cgcttcctgt ccactgcccc ctccccatcc ccagcccagc cgagggaatc     4620

ccgtgggttg cttacctacc tataaggtgg tttataagct gctgtcctgg ccactgcatt     4680

caaattccaa tgtgtacttc atagtgtaaa aatttatatt attgtgaggt tttttgtctt     4740

tttttttttt tttttttttt ggtatattgc tgtatctact ttaacttcca gaaataaacg     4800

ttatatagga accgtaaaa                                                  4819


<210>  2442
<211>  4330
<212>  DNA
<213>  homo sapiens

<400>  2442
ggaaacattt ctaggtccga gccagcggcc taactggagt gtgcgcattc gaccgagcac       60

agacacgttg cccaccgctc ctctcccgag gtctgtagtc gcggagaaac acatgttgcg      120

ttactaacgt tcagaggtct gcgacagctt cgatttgaat gactagccgg gaacaccaag      180

tttcactgtg taattgcgtc cccctactcc ggcgcctcct ttgcgacgct ccctggagaa      240

aagcacgccc actgcacgcg ctcagtcgct acttccgctc tcgagtgtct ccaagcaaga      300

tggcggagga gccgcagtct gtgttgcagc ttcctacttc aattgctgct ggaggggaag      360

gacttacgga tgtctcccca gaaacaacca ccccggagcc cccgtcttcc gctgcagttt      420

ccccgggaac agaggaacct gctggcgaca ccaagaaaaa aattgacatt ttgctaaagg      480

ctgtgggaga cactcctatt atgaaaacaa agaagtgggc agtagagcga acacgaacca      540

tccaaggact cattgacttc atcaaaaagt ttcttaaact tgtggcctca gaacagttgt      600

ttatttatgt gaatcagtcc tttgctcctt ccccagacca agaagttgga actctctatg      660

agtgttttgg cagtgatggt aaactggttt tacattactg caagtctcag gcgtggggat      720

gaaccacaaa gaaaatcaac ttgctactac atgaaatgga ttttcacgga agagacagct      780

ctgaaaagtt ttgatgcttg tggcaagaga cttaacagat gtgatctatt tagtatgtgt      840

ctactctatg tttatgcata agaaaacatc catagcatga atggactcag aaaaatgtga      900

tttgtattaa tgcaccagtc atcataaaag atggtcatga tagtacaccc attgctccta      960

cttgttacta ttattgctgc agatctgcct ccaaggttga aaaggagact aagactgtat     1020

aaacatcttc attgtcagtt ctcaaaatga ctgaaattgt tttcatggta aaagttaata     1080

tactaaaggg ttcctttttt tttaatgttt acatttatct ctatgtttac ctttttagtc     1140

acattgacct gctggctgaa tacctcaaat agtccagtag agggcagtcc accaggcaga     1200

aaaggttagg cgttttggtt tcacatcttt gctggggaat aataggggaa atggctgttt     1260

ttgctaattt ttagctaata tctagccagg agagcaagca cataggacag actgaaagac     1320

tgtaatttta cacaatacac atggcttaat tattttattg ggatacagaa aaatataaat     1380

tctggacaaa taagtcatat acctgttttc agtcctaaca tttaaggatt cttgagtccc     1440

aatcacataa ctgtggtgtt actctgtcat ttatatggtg tcaaaagcac ttgatgagta     1500

aacccagtag catctttttg agtgtttcat aatgcatttt ccaacttgaa aacaataatt     1560

gaaaaatagc cttattgtat attttatgcc atgactaaaa gtgccatttt tactgatgct     1620

attagactga taatttcttg aagtgaaatt taaccttttt ttctctttag tattatgttt     1680

ataatgccat atttttagaa agcattccag atcaggcatg gtggcttaca cctgtaatcc     1740

cagcactttg gaaggctgag gtgtggggat tgcgtgaagc cacaagtttg agaccagcct     1800

ggttagcaag gcaagatccc caactctaca aaaaaataaa aattaaaaaa aaattattag     1860

gctgcagagg caagaggatc ccctgagccc agaagttcaa gggtatagtg agtcgtgatt     1920

gtaccactgc attcctgctg agcaacagag tgagacccca tctcaaaaaa gaaaaaaaaa     1980

ggcattctag taaatcgaat gtaatgtgaa tggaatttca aaacaggatc taagatggta     2040

tgtagtagaa ttcaaagtaa tatcatttta aagttaaatg agtatggaaa aggtctgttc     2100

tctagttttg tccagttcag tttactgaag gaatatattt aattatattc atatatttaa     2160

caaataaaaa tatgttgaat tttcgtattg tttgccactg agggttcaga tgatagacct     2220

caaaaaatcg aaaatactgg ttgaaatttg tagcatccat ttagttattc tttttgacct     2280

aaataactta atagtttatt aaatctaagg ttagctaaat atgtagctaa ccttatttgt     2340

tttctttcct aacaactctg aagaatacat aggactttgc actttttttt tttttttttt     2400

tttttaaaga gacagcgttt cggtcttgtt gcccaggctg gactgtaatg gcacaatctt     2460

ggctcattgc aacctctacc tcccgggttc aagtgattct cctgcctcag cctcctgagt     2520

agctgggatt acaggcacct gccaccacac ccgcctaatt ttttgttatt tttagtggag     2580

acagggtttt accattttgg ccaggctggt ctcaaactcc tgactgacct caggtgatcc     2640

acccgccttg gcctcccaaa gtgctgggat tataggtgtg agccaccgtg ccgggcctgg     2700

actttgtact ttttcaaatc atatttaatt atttcttgat ctttactcaa agaattattc     2760

tgcgctaaat ttgcaacatt aaacaataat taagcctgga tccgataagt tattgggtga     2820

ctagaaccta caacacaatt tatttttaat ttaaactctc aagtctgatt aaacttgggg     2880

gaaaaactga acattcaggt gatattttaa attttctttg tgactaaata gatgtcatta     2940

atatcatgct tcatcttact gtgcatagat gacccatggc acacaaagta tatgtataat     3000

attgcaatat tgtacttcca tctttaaaag tatgccaaag acttcataat gaattcacca     3060

tatttaagga ataaggcaaa ttaatgttta tccgaaatca aaatgagatt ggataattcc     3120

tggaatctga tttctgtaag tttcagtcct aaagggacct taaatatcta ctagaacgaa     3180

gtacagtgta tttctcagat tacatgacat tagtcaacca atttagttgt aacacaaagt     3240

gagaaagcct taggtgttga aggagtgtga aaataaaaat ctcttttcat gcagtttctg     3300

cttcattttc caaggattat aatatgctga gtaaactttt ggcactaagg aagccagcta     3360

caggccacgt aatgaaaact attcagaaaa cagttcagca aatactacta tttgaataca     3420

gttcaaatcg tatttatata aatactctgc ctacattatt taacccaaac tggattattc     3480

accattcttt gaagatgcct tgtgttttct gttatctact tctgctcgtg cagtttactt     3540

acaccttcac cctttcaaat cctaactctt cttcaaggcc tgattcagat tttaactttt     3600

taaaggctat ctgaatcatt caaggagaag ataccctttc tctcataaaa acacttagag     3660

caaactacca ctattaaatc acttattgca tactgcctca gagccatgtg tccagttatt     3720

ctggttttta tctggtaccc acacacacat aatacttagt acatttcctt atatgtaaat     3780

aattagtaat gtaacacatc gagtgaatga aattgtgatt agcaaagtat gacagctaaa     3840

aacaaaggaa attttgtata gtttaagttt ttgtacagca gaaggtaatg gaaaatattt     3900

gcaacatatg acagtgtttt taatgtctta agtatatgaa gaatttgttt caattggtaa     3960

gaaaagacca actgaaaaat aggcaaaaca taccaaattt cgattcacaa aaagatacaa     4020

atggccaaca aaacatgaaa caccttgaac cccattggtt acaaaaaata caaataaaaa     4080

caatgctgac tgacaataaa aataatgtac atcttgctat tagcagagtt gtggggaaat     4140

cctgtcatat tttggtgaat agaatatgag ttggtatatc acttttaggg ggccatttgg     4200

caatatcaaa aaccttgaaa cgtaagtata aacttcagtt tgttcgtata acctgtcatt     4260

cacatattga gtgcctacta tgtcctaaat attggaataa cactaataaa gctcataaga     4320

gactaataaa                                                            4330


<210>  2443
<211>  1572
<212>  DNA
<213>  homo sapiens

<400>  2443
tagtgtcacg tgaggccccg gtggcggcgc agctacggca agagagtgag aaggaaggga       60

agccggaagg ggcgcgagtg aagcaaagcg aggacagaca gctcgcagag ggcgaggggt      120

gcgtgtgcgt ccgcttctca cctcaggtct cccttcggcc ccgctgccct ccctcgcggc      180

tgggtgacag ctgggtccgg tccgtcgcgg gctgcctggg gtgcgaggat cgcgcacccc      240

gtcttcgcgc gctgtgcctg ccgccccgcc ccctcgtccc gcccgtcccg tcgcgtcgcg      300

tcccgtcccc tcgggtgctg ccagccgggt gctgatgcga gtcggtggca gcgaggacat      360

tttctgactc cctggcccct gacacggctg cactttccat cccgtcgcgg ggccggccgc      420

tactccggcc ccaggatgca gaatgtgatt aatactgtga agggaaaggc actggaagtg      480

gctgagtacc tgaccccggt cctcaaggaa tcaaagttta aggaaacagg tgtaattacc      540

ccagaagagt ttgtggcagc tggagatcac ctagtccacc actgtccaac atggcaatgg      600

gctacagggg aagaattgaa agtgaaggca tacctaccaa caggcaaaca atttttggta      660

accaaaaatg tgccgtgcta taagcggtgc aaacagatgg aatattcaga tgaattggaa      720

gctatcattg aagaagatga tggtgatggc ggatgggtag atacatatca caacacaggt      780

attacaggaa taacggaagc cgttaaagag atcacactgg aaaataagga caatataagg      840

cttcaagatt gctcagcact atgtgaagag gaagaagatg aagatgaagg agaagctgca      900

gatatggaag aatatgaaga gagtggattg ttggaaacag atgaggctac cctagataca      960

aggaaaatag tagaagcttg taaagccaaa actgatgctg gcggtgaaga tgctattttg     1020

caaaccagaa cttatgacct ttacatcact tatgataaat attaccagac tccacgatta     1080

tggttgtttg gctatgatga gcaacggcag cctttaacag ttgagcacat gtatgaagac     1140

atcagtcagg atcatgtgaa gaaaacagtg accattgaaa atcaccctca tctgccacca     1200

cctcccatgt gttcagttca cccatgcagg catgctgagg tgatgaagaa aatcattgag     1260

actgttgcag aaggaggggg agaacttgga gttcatatgt atcttcttat tttcttgaaa     1320

tttgtacaag ctgtcattcc aacaatagaa tatgactaca caagacactt cacaatgtaa     1380

tgaagagagc ataaaatcta tcctaattat tggttctgat ttttaaagaa ttaacccata     1440

gatgtgacca ttgaccatat tcatcaatat atacagtttc tctaataagg gacttatatg     1500

tttatgcatt aaataaaaat atgttccact accagcctta cttgtttaat aaaaatcagt     1560

gcaaagagag tt                                                         1572


<210>  2444
<211>  1572
<212>  DNA
<213>  homo sapiens

<400>  2444
tagtgtcacg tgaggccccg gtggcggcgc agctacggca agagagtgag aaggaaggga       60

agccggaagg ggcgcgagtg aagcaaagcg aggacagaca gctcgcagag ggcgaggggt      120

gcgtgtgcgt ccgcttctca cctcaggtct cccttcggcc ccgctgccct ccctcgcggc      180

tgggtgacag ctgggtccgg tccgtcgcgg gctgcctggg gtgcgaggat cgcgcacccc      240

gtcttcgcgc gctgtgcctg ccgccccgcc ccctcgtccc gcccgtcccg tcgcgtcgcg      300

tcccgtcccc tcgggtgctg ccagccgggt gctgatgcga gtcggtggca gcgaggacat      360

tttctgactc cctggcccct gacacggctg cactttccat cccgtcgcgg ggccggccgc      420

tactccggcc ccaggatgca gaatgtgatt aatactgtga agggaaaggc actggaagtg      480

gctgagtacc tgaccccggt cctcaaggaa tcaaagttta aggaaacagg tgtaattacc      540

ccagaagagt ttgtggcagc tggagatcac ctagtccacc actgtccaac atggcaatgg      600

gctacagggg aagaattgaa agtgaaggca tacctaccaa caggcaaaca atttttggta      660

accaaaaatg tgccgtgcta taagcggtgc aaacagatgg aatattcaga tgaattggaa      720

gctatcattg aagaagatga tggtgatggc ggatgggtag atacatatca caacacaggt      780

attacaggaa taacggaagc cgttaaagag atcacactgg aaaataagga caatataagg      840

cttcaagatt gctcagcact atgtgaagag gaagaagatg aagatgaagg agaagctgca      900

gatatggaag aatatgaaga gagtggattg ttggaaacag atgaggctac cctagataca      960

aggaaaatag tagaagcttg taaagccaaa actgatgctg gcggtgaaga tgctattttg     1020

caaaccagaa cttatgacct ttacatcact tatgataaat attaccagac tccacgatta     1080

tggttgtttg gctatgatga gcaacggcag cctttaacag ttgagcacat gtatgaagac     1140

atcagtcagg atcatgtgaa gaaaacagtg accattgaaa atcaccctca tctgccacca     1200

cctcccatgt gttcagttca cccatgcagg catgctgagg tgatgaagaa aatcattgag     1260

actgttgcag aaggaggggg agaacttgga gttcatatgt atcttcttat tttcttgaaa     1320

tttgtacaag ctgtcattcc aacaatagaa tatgactaca caagacactt cacaatgtaa     1380

tgaagagagc ataaaatcta tcctaattat tggttctgat ttttaaagaa ttaacccata     1440

gatgtgacca ttgaccatat tcatcaatat atacagtttc tctaataagg gacttatatg     1500

tttatgcatt aaataaaaat atgttccact accagcctta cttgtttaat aaaaatcagt     1560

gcaaagagag tt                                                         1572


<210>  2445
<211>  8931
<212>  DNA
<213>  homo sapiens

<400>  2445
cttcccgcac tgcttgggga gagctggtga gcaagagtct ggcccgagtt agctagagct       60

gttgccatga caagcatttt cttaagaaag ctctgctgtt gagatcgtcc aaagctgggg      120

gctgggaggg ggggcacgaa cttcgtgggg caccatccct ccgaagagag caagatcaga      180

gacacccgcc cagctctcct gcaccctttt tctttcagga acctgagagg tccttcccat      240

tggaggggca gggggaggag acccagccca ctccccggcc ttagccagaa aggcaagaga      300

gcaaagccag cgtctctagc ttggttgcca cactggggag actggtgggt ggtcacccca      360

ccctaccctc atccatggaa acccggaggg agagtcccgc ctgaagaaac ctggatcttt      420

gctagaaaga gagagatcca gttgtcatcg gtatccagga agctctcctc ttcctcctcc      480

tgacgtctac tactacagtt gctggttgtt gctaaggttg ctgccatggt aacatgcaca      540

tcctgtttac accttcatct gggcaagttg gtctaagcta ggaacctacc taccctggac      600

aactactatc atcaccacct ggggacacca atcatcgtga cacggagtcc accttccact      660

cagttccccc atcctcttcc tcctctcgct gccagacttc atacggaaga aaggatctag      720

acttcggacg gctactcggg agcttattgc acaagatata ttcaatctat tccctcactg      780

ggcccccaga gaagcaagaa gtaggaagaa gttgagacag ggaggcagga gacactggtc      840

agttgaaggg aaacgctaca tcttctctgg ttgaggggct tggtaacagc aggcaaaatg      900

acgaacccat cagaccgtgt cttgcctgcc aactcgatgg ccgagagccg tgaaggggac      960

tttggctgca cagtaatgga actgaggaag ctcatggagc tgcgttcaag ggatgcactg     1020

acccagatta atgtccacta tggaggtgta cagaatctct gcagtagact gaaaacctcc     1080

cctgtggaag gtctgtctgg gaaccctgca gatctggaga aacgtaggca ggtgtttgga     1140

cacaacgtga tcccccccaa aaagcccaag actttcttag aattagtgtg ggaagctctt     1200

caagatgtca cgcttatcat cctggagatt gcagccatca tctccctggt cctgtccttt     1260

tatcgccctg ctggtgaaga aaatgaactg tgtggtcaag tcgcaactac cccagaagat     1320

gaaaatgagg cacaagctgg ctggattgag ggggcagcca tccttttctc agtgatcatc     1380

gtggtgttag tgactgcctt taatgattgg agcaaagaga agcaattccg ggggctgcag     1440

tgccgcattg aacaggagca aaagttctcc atcatccgaa acggtcaact catccagctc     1500

cctgtggctg agattgtggt tggtgatatt gcccaagtca aatacggtga tctgctgcct     1560

gcagatggaa tcctgatcca agggaatgat ctgaagattg atgagagctc tctgacaggg     1620

gaatctgacc atgtcaagaa gtccctggac aaagacccca tgttgctctc agggacccat     1680

gtcatggaag gttctggccg gatggtggtg acagctgttg gtgtcaactc tcagactgga     1740

atcatcctta ctctcttggg ggtcaatgag gatgacgaag gggagaaaaa gaagaaaggt     1800

aaaaaacaag gagtccctga aaatcgcaac aaagcaaaga cccaagacgg agtggccctg     1860

gaaatccagc cactcaacag ccaggaggga atcgacaatg aggaaaagga caagaaggca     1920

gtcaaggtgc ctaaaaagga gaagtcagtg ctgcagggca agctgactcg cctggctgtt     1980

cagattggga aagccggtct gctcatgtct gctctcacgg ttttcatcct gattctatac     2040

tttgtgattg acaactttgt gataaatcgc agaccatggc tccctgagtg tactcccatc     2100

tacatccagt actttgtcaa gttcttcatc atcggcatca ctgtactggt ggtggctgtg     2160

ccagaggggc tgcctctggc tgtcaccatc tcactggcct actctgtgaa gaaaatgatg     2220

aaagacaata acctagtacg gcacttggat gcttgtgaga ccatgggcaa cgccaccgcc     2280

atctgctctg ataagacagg cacgttgacc atgaaccgca tgactgtggt acaagcttat     2340

attgggggca tccattaccg tcaaatccca agccctgatg tcttcctgcc caaagtcctg     2400

gacctcattg tcaatggcat ttctatcaac agtgcttata cctccaagat tctgcctcca     2460

gagaaggagg gaggcctgcc tcggcaggtg ggcaacaaga ccgagtgtgc tctgctaggc     2520

tttgtcacag atctgaagca ggattatcag gctgtgcgta atgaagtgcc cgaggagaag     2580

ctctacaagg tgtacacctt taactcagtg cgcaagtcaa tgagcaccgt catcaggaat     2640

cccaacggtg gcttccgtat gtacagcaag ggcgcctctg agatcatctt gcgcaagtgt     2700

aatcgaatcc tggaccggaa aggggaagca gtgccattca agaataaaga cagagatgat     2760

atggtacgca ctgtcatcga gcccatggcc tgtgatggac tccggactat ctgcatagct     2820

taccgggact tcgatgacac agagccctct tgggacaatg agaatgagat cctcaccgaa     2880

ctgacctgta tcgcggtggt gggcattgag gaccctgtgc gcccagaggt gccagatgct     2940

attgccaaat gcaaacaagc tggcattact gtcagaatgg tgacaggtga caacatcaac     3000

acagcccggg ccattgccac caaatgtggc attctgacac ctggggatga cttcctgtgc     3060

ttagaaggca aagaattcaa ccggctcatc cgcaacgaga aaggcgaggt agagcaagaa     3120

aagctggaca agatctggcc taagcttcgg gtcctggcgc gatcttctcc cactgacaag     3180

cacaccctgg tgaaaggcat aattgacagc actgttgggg aacaccggca ggtcgtggct     3240

gtcactggtg atggcacaaa tgacgggcct gctctgaaga aagcggatgt tggttttgcc     3300

atgggcatcg caggcacaga tgtagcaaag gaggcttcag acatcatcct aacagatgac     3360

aacttcacca gcattgtgaa ggcagtgatg tggggacgaa atgtctatga cagcatctcc     3420

aagttcctgc agttccagct cactgtcaat gtggtggccg tgattgtagc cttcactgga     3480

gcctgtatca ctcaggattc cccattgaaa gctgtgcaga tgttgtgggt taatctgatc     3540

atggacactt ttgcttcatt ggccctggcc acagagcccc ctacggaatc tctgttgaag     3600

cggcgcccct atggccgaaa taagcctctg atctcacgca ctatgatgaa gaacatcttg     3660

ggccatgcat tctatcagct cattgtcatc tttatccttg tctttgcggg tgagaaattc     3720

tttgatattg atagtgggag gaaggcacct ctacattcac cacccagcca gcactatacc     3780

attgttttta acaccttcgt gctgatgcag ctcttcaatg aaatcaactc ccgaaagatc     3840

catggagaga agaacgtctt ttcaggcatc taccgcaaca ttatcttctg ctctgtagtc     3900

ttgggcacat tcatctgcca gattttcatc gtggaatttg ggggtaaacc cttcagttgt     3960

acaagcctca gcctgtctca gtggctgtgg tgtctcttca ttgggattgg agaacttctg     4020

tggggccagt tcatctccgc aatacctacc cgatccctga agttcctgaa ggaggctggg     4080

catggcacca ccaaagagga gatcaccaag gatgccgagg gactggatga gattgaccat     4140

gctgagatgg agctgcgccg aggccagatc ctctggttcc ggggcctgaa ccgtatccag     4200

actcagatcg acgtaattaa cacattccag acgggagcct cttttaaggg agtcctaagg     4260

cgacagaaca tgggtcaaca ccttgatgta aaacttgttc ctagttcatc ctatgtagca     4320

gttgcaccag tcaaatcttc ccccaccact tctgttcctg ctgtttcatc tcctcctatg     4380

ggcaatcaaa gtggtcaaag cgttccatag ttccctccac gaaagcattc agaaacccta     4440

caaccaaaag tccatccaca gcttcatgac ccaccctgaa ttcgccatag aggaggagtt     4500

gccacgaaca ccactcctgg atgaggaaga ggaggaaaat cctgacaagg cttctaagtt     4560

tgggactagg gtgctcctgt tggatggtga ggtcactcca tatgccaata caaacaacaa     4620

tgcggtggat tgcaaccaag tgcagctccc ccagtcggac agctctctac agagcctaga     4680

gacatcagtt tgaattttct ttctctgact ctcatcccta ttttacctat ttccattttc     4740

gtctatccca tctatgaggt gatgatggga cttttcattg tcacgtcagc tgctgtgtta     4800

acagcagtgt gtgtgaagtg aacctctacc tgaccatgaa gaggcaagag cacagactta     4860

caaggatttc aacttaagct tgacttgggg tttgtagcgg gacccagtca aaccccattc     4920

aggtcatggt agaatctact ccttggtagt cacttgtcat ttttaaagaa atgatgacaa     4980

tcctcttggc atcaccccac cccacattct ccccgatgtt cctctcctga attctggatt     5040

ttgtcctaca agtctgtgcc atttataagc taagttgagg gttcagaggg agacaaatat     5100

ccccaagtga aatatgttgc ggtagagatg gaatgtataa aatccgccag tagtgtgatt     5160

gtttttcaat ttttcccact ttgaaaactt acacctaaag gcctgtaggc ctctaactct     5220

ttctgccctt tcattcaaac ctctccaaag ttctttgtct tttgtcttcc cttcctttcc     5280

tttttttttt ttttttttat gatgattaag aaaatggaaa ggatatggat gaattgtgta     5340

aacttagatc cttctccctt ttggcccaaa agaacccttg atttagttcc agaatccaac     5400

cagtttcttt gttaaaaggg tccttttgaa gcaattaagt gctggtaaga atatttctct     5460

gttgttgcca ggttaccttc tgcttttaaa ttgccatctt gtaaagtgta tgtggttctt     5520

aagtgccagg gagatcagcc ttgcccatga aggttgcata tgtgtggtat acagttttta     5580

cctgaaagcc tgagctttct cttattccta aagtggtggc aaaagaatga actgggtatg     5640

accctgcccc cttactgggc ttggatattg aggaccagac gctgccaaat ctaggacaag     5700

acagaccatc aaagcagact tttgtgggct cctctttggg gtgaccactg ctttcaaagc     5760

catctgccaa ggctctccag ggcaggacct gactggtggg gaatgagtgt tcagaagcct     5820

tgggagaggc caaagagcca ttctagcatg atctgagaaa accttcctgc agaggccaga     5880

aaccttgagc ttaggtgcct ggggaccagc ttcgacattc tctccagttt ctgattctaa     5940

tttttgccac gtgtcacaac ttttccagtc tctgagaagg tcccagcctt tctcaaatat     6000

tctgattttg aaaatatgta tccaaagtgg gaggcccctg tgacattttg ccaacttaaa     6060

cgagaaaaag accccccgca cccggcacac tcccccttcc tccagccccg cttcagccac     6120

atgctccagc tgctgcccag taaagccctg tgcctttttt tcccctgaat actgcccaaa     6180

gcatcccctt cccatctgcc tctcaggagt tggggacttt gctaggagat tttttaagtg     6240

ttccttactg ggacaacgtg gagccacgtt tgcaggagct ccatttgtat ccctgctggt     6300

gttgacttct gtgtaggggc cagttcatgt ccctgactct cacctcccat tagataaatg     6360

aagcccaccc ccctttctag agtgatgaga gtcaagaaga ggggatgtat gaacggccaa     6420

attcccatgt gagaggaaga tgacctgatc cacctagcct tttcttctgg atctgtcctc     6480

cctcacccct ttcacctgag ctgtccacag taggaaacat aaagaaacaa tgtcccctac     6540

atatccccat gactacataa tccatcatcg taggaaatag gaaagcaaat ttgattttgg     6600

ttttgtaaaa cgtacatgct tcaataattc ttttttgtgt cttaaatact cataggggaa     6660

aaaaacagct cacccaaggt gttaggtttc acatatatat tcatcaacta ttttagaaga     6720

tttaattcta tcaaatcttg tattacctca gatcatttta aatagcaagc caataacgag     6780

ctttgaaggc tattttacca ttcctgttca caaaaggttc tcatggtgcc tgacaggtta     6840

cccttgaggg cttgtgtcta ctttttaaaa gtcaatggtt ttttttcttg tgttctagtt     6900

tccataatag gagagaaaat atagaaatat atgcaaaaat tatagttttc tttagatcag     6960

aaactgatat ttttgggtca gccatatgta ttttgtttaa aggatttaaa ataaagtgcc     7020

gtcatgtagc cctgtggaag ggagcacata accagctgtt tggcatgaca ggtgacttag     7080

tatatttgta attggtttta aaaccaatac accatacttt ctttctgcaa acagccatct     7140

ttatacttag ggaagaaaaa ttgttgggtt ctagactttt ttaatataaa ttttgttgat     7200

atggaattag gtaagtttaa gtgtctatgt gcatatgttt tttatataag ttttttctat     7260

tcagtttcac tgatccaact ggcagtgggt aaatatggca taagttaata acacttttcc     7320

ccaaaatggt gctttggatt tgaaaagggt ctgatgggga gaaggagaac gtatcatcct     7380

agcttcctct cttaataaac ctagaaaaac gggtagtaaa ctgtggatag tcaggaaaac     7440

acccagcaag ggacacagct gtcaggaaat gaatcttccc cccaaccccc accatgcaga     7500

tggatagaca gaatctttcc tgactagtca ttaggatcag gggcctctgt tggatttgtg     7560

tttcttgaag aatagctggc agagtggtat aaaagacacg aatatctcct ggtctataag     7620

gatactctga tttggggttt gcatttttca tggtttttat ttcctgttcc ccctggagtt     7680

ttccattagt gagtttttgt gcaaggatct tatttgtgat gccttccctc ccctagaaag     7740

attttgtgca atatattaaa tggggacaga attctaaatg gataaaacaa tggctggttc     7800

tagccctgag tgacagtctt aaggctagat ccttcccata gtatcatctg tcctctggaa     7860

tgactctcct gtccctaaag gggttaagag agagatcacc tagaaatccc tctggacact     7920

tgtgggttct ttagggtttg agtttcttct tccccttgag cttcagagag gagagttggc     7980

atggttaaat ctgaatggtt acctcactgc tgaaaaccca gaggggcgtg gcacactcgc     8040

ttgtgtggaa aagcctctaa atgcatccct tcctttcttt cctgcttcct ttgccttaca     8100

attgaagcag cccgtggtac catcacagta tgcagagact tcctcacctt tcatatctag     8160

ggaccacccc cgatgcattg gtgagggtgg gcacttataa atgcctgcta ttgttaagcc     8220

attccagcct cttcctctga atagaccaga cgccctttca cttagttcag tgccagtcct     8280

tttgccttcc caaccctgct gttaggcctg ctgttccctt tgctcttgat taggagagat     8340

ggaaggagat gagctcccat aactgaattg gcctttggtt catgttttct ccccatatgt     8400

atatatgcca tatgtgaata tgccatatat atgtgccaac aaatctatct acgttgttct     8460

tttcaaatta gcacgcagat aggaattttg agtttcttct tcttttagta actagtataa     8520

caagcactgg tatttttgta caaaaaagaa aaacaaaaga ttgactattg tggtctgcat     8580

gacataaaca aacaaatggt gatatcaaag caacgtatac cccagtccag tgtgtgttgc     8640

cataatttgc aattcagctt aacagtgcac ccaatctata tttgcatttt gatattattt     8700

aagctctatg tacaaggttt tgcatgtatt tatatggttc ttagggaaaa aaaatgctat     8760

aaactgcaaa tctgaaattc aaatgtgttg ttccactgag accagaagaa gaagaggagt     8820

tttaaaaggg ataatttgtt ggagccaata aagctttttg ctgatgaaca gaaaccaata     8880

ctgctgtgca ctgagaataa aaactcatgc ccacttgtaa aaaaaaaaaa a              8931


<210>  2446
<211>  3086
<212>  DNA
<213>  homo sapiens

<400>  2446
gttttgagca aaattttgga ctgtgaagca aggcattggt gaagacaaaa tggcctcgcc       60

ggctgacagc tgtatccagt tcacccgcca tgccagtgat gttcttctca accttaatcg      120

tctccggagt cgagacatct tgactgatgt tgtcattgtt gtgagccgtg agcagtttag      180

agcccataaa acggtcctca tggcctgcag tggcctgttc tatagcatct ttacagacca      240

gttgaaatgc aaccttagtg tgatcaatct agatcctgag atcaaccctg agggattctg      300

catcctcctg gacttcatgt acacatctcg gctcaatttg cgggagggca acatcatggc      360

tgtgatggcc acggctatgt acctgcagat ggagcatgtt gtggacactt gccggaagtt      420

tattaaggcc agtgaagcag agatggtttc tgccatcaag cctcctcgtg aagagttcct      480

caacagccgg atgctgatgc cccaagacat catggcctat cggggtcgtg aggtggtgga      540

gaacaacctg ccactgagga gcgcccctgg gtgtgagagc agagcctttg cccccagcct      600

gtacagtggc ctgtccacac cgccagcctc ttattccatg tacagccacc tccctgtcag      660

cagcctcctc ttctccgatg aggagtttcg ggatgtccgg atgcctgtgg ccaacccctt      720

ccccaaggag cgggcactcc catgtgatag tgccaggcca gtccctggtg agtacagccg      780

gccgactttg gaggtgtccc ccaatgtgtg ccacagcaat atctattcac ccaaggaaac      840

aatcccagaa gaggcacgaa gtgatatgca ctacagtgtg gctgagggcc tcaaacctgc      900

tgccccctca gcccgaaatg ccccctactt cccttgtgac aaggccagca aagaagaaga      960

gagaccctcc tcggaagatg agattgccct gcatttcgag ccccccaatg cacccctgaa     1020

ccggaagggt ctggttagtc cacagagccc ccagaaatct gactgccagc ccaactcgcc     1080

cacagagtcc tgcagcagta agaatgcctg catcctccag gcttctggct cccctccagc     1140

caagagcccc actgacccca aagcctgcaa ctggaagaaa tacaagttca tcgtgctcaa     1200

cagcctcaac cagaatgcca aaccagaggg gcctgagcag gctgagctgg gccgcctttc     1260

cccacgagcc tacacggccc cacctgcctg ccagccaccc atggagcctg agaaccttga     1320

cctccagtcc ccaaccaagc tgagtgccag cggggaggac tccaccatcc cacaagccag     1380

ccggctcaat aacatcgtta acaggtccat gacgggctct ccccgcagca gcagcgagag     1440

ccactcacca ctctacatgc accccccgaa gtgcacgtcc tgcggctctc agtccccaca     1500

gcatgcagag atgtgcctcc acaccgctgg ccccacgttc cctgaggaga tgggagagac     1560

ccagtctgag tactcagatt ctagctgtgg tgagaaaccc tatcgttgca acatctgtgg     1620

ggcccagttc aaccggccag ccaacctgaa aacccacact cgaattcact ctggagagaa     1680

gccctacaaa tgcgaaacct gcggagccag atttgtacag gtggcccacc tccgtgccca     1740

tgtgcttatc cacactggtg agaagcccta tccctgtgaa atctgtggca cccgtttccg     1800

gcaccttcag actctgaaga gccacctgcg aatccacaca ggagagaaac cttaccattg     1860

tgagaagtgt aacctgcatt tccgtcacaa aagccagctg cgacttcact tgcgccagaa     1920

gcatggcgcc atcaccaaca ccaaggtgca ataccgcgtg tcagccactg acctgcctcc     1980

ggagctcccc aaagcctgct gaagcatgga gtgttgatgc tttcgtctcc agccccttct     2040

cagaatctac ccaaaggata ctgtaacact ttacaatgtt catcccatga tgtagtgcct     2100

ctttcatcca ctagtgcaaa tcatagctgg gggttggggg tggtgggggt cggggcctgg     2160

gggactggga gccgcagcag ctccccctcc cccactgcca taaaacatta agaaaatcat     2220

attgcttctt ctcctatgtg taaggtgaac catgtcagca aaaagcaaaa tcattttata     2280

tgtcaaagca ggggagtatg caaaagttct gacttgactt tagtctgcaa aatgaggaat     2340

gtatatgttt tgtgggaaca gatgtttctt ttgtatgtaa atgtgcattc ttttaaaaga     2400

caagacttca gtatgttgtc aaagagaggg ctttaatttt tttaaccaaa ggtgaaggaa     2460

tatatggcag agttgtaaat atataaatat atatatatat aaaataaata tatataaacc     2520

taaaaaagat atattaaaaa tataaaactg cgttaaaggc tcgattttgt atctgcaggc     2580

agacacggat ctgagaatct ttattgagaa agagcactta agagaatatt ttaagtattg     2640

catctgtata agtaagaaaa tattttgtct aaaatgcctc agtgtatttg tatttttttg     2700

caagtgaagg tttacaattt acaaagtgtg tattaaaaaa aacaaaaaga acaaaaaaat     2760

ctgcagaagg aaaaatgtgt aattttgttc tagttttcag tttgtatata cccgtacaac     2820

gtgtcctcac ggtgcctttt ttcacggaag ttttcaatga tgggcgagcg tgcaccatcc     2880

ctttttgaag tgtaggcaga cacagggact tgaagttgtt actaactaaa ctctctttgg     2940

gaatgtttgt ctcatcccat tctgcgtcat gcttgtgtta taactactcc ggagacaggg     3000

tttggctgtg tctaaactgc attaccgcgt tgtaaaatat agctgtacaa atataagaat     3060

aaaatgttga aaagtcaaac tggaaa                                          3086


<210>  2447
<211>  3575
<212>  DNA
<213>  homo sapiens

<400>  2447
accatcgtct tgggcccggg gagggagagc caccttcagg cccctcgagc ctcgaaccgg       60

aacctccaaa tccgagacgc tctgcttatg aggacctcga aatatgccgg ccagtgaaaa      120

aatcttgtgg ctttgagggc ttttggttgg ccaggggcag taaaaatctc ggagagctga      180

caccaagtcc tcccctgcca cgtagcagtg gtaaagtccg aagctcaaat tccgagaatt      240

gagctctgtt gattcttaga actggggttc ttagaagtgg tgatgcaaga agtttctagg      300

aaaggccgga caccaggttt tgagcaaaat tttggactgt gaagcaaggc attggtgaag      360

acaaaatggc ctcgccggct gacagctgta tccagttcac ccgccatgcc agtgatgttc      420

ttctcaacct taatcgtctc cggagtcgag acatcttgac tgatgttgtc attgttgtga      480

gccgtgagca gtttagagcc cataaaacgg tcctcatggc ctgcagtggc ctgttctata      540

gcatctttac agaccagttg aaatgcaacc ttagtgtgat caatctagat cctgagatca      600

accctgaggg attctgcatc ctcctggact tcatgtacac atctcggctc aatttgcggg      660

agggcaacat catggctgtg atggccacgg ctatgtacct gcagatggag catgttgtgg      720

acacttgccg gaagtttatt aaggccagtg aagcagagat ggtttctgcc atcaagcctc      780

ctcgtgaaga gttcctcaac agccggatgc tgatgcccca agacatcatg gcctatcggg      840

gtcgtgaggt ggtggagaac aacctgccac tgaggagcgc ccctgggtgt gagagcagag      900

cctttgcccc cagcctgtac agtggcctgt ccacaccgcc agcctcttat tccatgtaca      960

gccacctccc tgtcagcagc ctcctcttct ccgatgagga gtttcgggat gtccggatgc     1020

ctgtggccaa ccccttcccc aaggagcggg cactcccatg tgatagtgcc aggccagtcc     1080

ctggtgagta cagccggccg actttggagg tgtcccccaa tgtgtgccac agcaatatct     1140

attcacccaa ggaaacaatc ccagaagagg cacgaagtga tatgcactac agtgtggctg     1200

agggcctcaa acctgctgcc ccctcagccc gaaatgcccc ctacttccct tgtgacaagg     1260

ccagcaaaga agaagagaga ccctcctcgg aagatgagat tgccctgcat ttcgagcccc     1320

ccaatgcacc cctgaaccgg aagggtctgg ttagtccaca gagcccccag aaatctgact     1380

gccagcccaa ctcgcccaca gagtcctgca gcagtaagaa tgcctgcatc ctccaggctt     1440

ctggctcccc tccagccaag agccccactg accccaaagc ctgcaactgg aagaaataca     1500

agttcatcgt gctcaacagc ctcaaccaga atgccaaacc agaggggcct gagcaggctg     1560

agctgggccg cctttcccca cgagcctaca cggccccacc tgcctgccag ccacccatgg     1620

agcctgagaa ccttgacctc cagtccccaa ccaagctgag tgccagcggg gaggactcca     1680

ccatcccaca agccagccgg ctcaataaca tcgttaacag gtccatgacg ggctctcccc     1740

gcagcagcag cgagagccac tcaccactct acatgcaccc cccgaagtgc acgtcctgcg     1800

gctctcagtc cccacagcat gcagagatgt gcctccacac cgctggcccc acgttccctg     1860

aggagatggg agagacccag tctgagtact cagattctag ctgtgagaac ggggccttct     1920

tctgcaatga gtgtgactgc cgcttctctg aggaggcctc actcaagagg cacacgctgc     1980

agacccacag tgacaaaccc tacaagtgtg accgctgcca ggcctccttc cgctacaagg     2040

gcaacctcgc cagccacaag accgtccata ccggtgagaa accctatcgt tgcaacatct     2100

gtggggccca gttcaaccgg ccagccaacc tgaaaaccca cactcgaatt cactctggag     2160

agaagcccta caaatgcgaa acctgcggag ccagatttgt acaggtggcc cacctccgtg     2220

cccatgtgct tatccacact ggtgagaagc cctatccctg tgaaatctgt ggcacccgtt     2280

tccggcacct tcagactctg aagagccacc tgcgaatcca cacaggagag aaaccttacc     2340

attgtgagaa gtgtaacctg catttccgtc acaaaagcca gctgcgactt cacttgcgcc     2400

agaagcatgg cgccatcacc aacaccaagg tgcaataccg cgtgtcagcc actgacctgc     2460

ctccggagct ccccaaagcc tgctgaagca tggagtgttg atgctttcgt ctccagcccc     2520

ttctcagaat ctacccaaag gatactgtaa cactttacaa tgttcatccc atgatgtagt     2580

gcctctttca tccactagtg caaatcatag ctgggggttg ggggtggtgg gggtcggggc     2640

ctgggggact gggagccgca gcagctcccc ctcccccact gccataaaac attaagaaaa     2700

tcatattgct tcttctccta tgtgtaaggt gaaccatgtc agcaaaaagc aaaatcattt     2760

tatatgtcaa agcaggggag tatgcaaaag ttctgacttg actttagtct gcaaaatgag     2820

gaatgtatat gttttgtggg aacagatgtt tcttttgtat gtaaatgtgc attcttttaa     2880

aagacaagac ttcagtatgt tgtcaaagag agggctttaa tttttttaac caaaggtgaa     2940

ggaatatatg gcagagttgt aaatatataa atatatatat atataaaata aatatatata     3000

aacctaaaaa agatatatta aaaatataaa actgcgttaa aggctcgatt ttgtatctgc     3060

aggcagacac ggatctgaga atctttattg agaaagagca cttaagagaa tattttaagt     3120

attgcatctg tataagtaag aaaatatttt gtctaaaatg cctcagtgta tttgtatttt     3180

tttgcaagtg aaggtttaca atttacaaag tgtgtattaa aaaaaacaaa aagaacaaaa     3240

aaatctgcag aaggaaaaat gtgtaatttt gttctagttt tcagtttgta tatacccgta     3300

caacgtgtcc tcacggtgcc ttttttcacg gaagttttca atgatgggcg agcgtgcacc     3360

atcccttttt gaagtgtagg cagacacagg gacttgaagt tgttactaac taaactctct     3420

ttgggaatgt ttgtctcatc ccattctgcg tcatgcttgt gttataacta ctccggagac     3480

agggtttggc tgtgtctaaa ctgcattacc gcgttgtaaa atatagctgt acaaatataa     3540

gaataaaatg ttgaaaagtc aaactggaaa aaaaa                                3575


<210>  2448
<211>  2055
<212>  DNA
<213>  homo sapiens

<400>  2448
gttgctatcc cagaatcctc agagaaggag tagcgcgttc gtgcgtccta gttccagtac       60

agcgtggagg gtttaggcag cgtgttctga ttctttgcgg gacggcgagc gcatttgtgc      120

tttgcccgcc gcggcctagg aggccttttg aggccgcgta gtcggtgttt ttgaactgac      180

tctacagctt ctggcaggcc gtgcggcgcc ctgacccggc ctcaccatgt tggtgctgtt      240

tgaaacgtct gtgggttacg ccatctttaa ggttctaaat gagaagaaac ttcaagaggt      300

tgatagttta tggaaagaat ttgaaactcc agagaaagca aacaaaatag taaagctaaa      360

acattttgag aaatttcagg atacagcaga agcattagca gcattcacag ctctgatgga      420

gggcaaaatc aataagcagc tgaaaaaagt tctgaagaaa atagtaaaag aagcccatga      480

accgctggca gtagctgatg ctaaactagg aggggtcata aaggaaaagc tgaatctcag      540

ttgtatccat agtcctgttg ttaatgaact tatgagagga attcgttcac aaatggatgg      600

attaatccct ggggtagaac cacgtgaaat ggcagctatg tgtcttggat tggctcacag      660

cctgtctcga tatagattga agtttagcgc tgataaagta gacacaatga ttgttcaggc      720

aatttccttg ttagatgact tggataaaga actaaacaac tacattatgc gatgtagaga      780

atggtatggc tggcatttcc ctgaattagg aaaaattatt tcagataatt taacatactg      840

caagtgttta cagaaagttg gcgataggaa gaactatgcc tctgccaagc tttctgagtt      900

gctgccagaa gaagttgaag cagaagtgaa agcagctgca gagatatcaa tgggaacaga      960

ggtttcagaa gaagatattt gcaatattct gcatctttgc acccaggtga ttgaaatctc     1020

tgaatatcga acccagctct atgaatatct acaaaatcga atgatggcca ttgcacccaa     1080

tgttacagtc atggttgggg aattagttgg agcacggctt attgctcatg caggttctct     1140

tttaaatttg gccaagcatg cagcttctac cgttcagatt cttggagctg aaaaggcact     1200

tttcagagcc ctcaaatcta gacgggatac ccctaagtat ggtctcattt atcatgcttc     1260

actcgtgggc cagacaagtc ccaaacacaa aggaaagatt tctcgaatgc tggcagccaa     1320

aaccgttttg gctatccgtt atgatgcttt tggtgaggat tcaagttctg caatgggagt     1380

tgagaacaga gccaaattag aggccaggtt gagaactttg gaagacagag ggataagaaa     1440

aataagtgga acaggaaaag cattagcaaa aacagaaaaa tatgaacaca aaagtgaagt     1500

gaagacttac gatccttctg gtgactccac acttccaacc tgttctaaaa aacgcaaaat     1560

agaacaggta gataaagagg atgaaattac tgaaaagaaa gccaaaaaag ccaagattaa     1620

agttaaagtt gaagaagagg aagaagaaaa agtggcagaa gaagaagaaa catctgtgaa     1680

gaagaagaag aaaaggggta aaaagaaaca cattaaggaa gaaccacttt ctgaggaaga     1740

accatgtacc agcacagcaa ttgctagtcc agagaaaaag aagaaaaaga aaaaaaagag     1800

agagaacgag gattaacaga aaggaattac gattatatca cccggacaca catcatgctt     1860

aagattcaac tgggagcata ccagggatgc tctctaacgt aatcaaggga aggttcagta     1920

agacaaagtg atttatcatc tataacttca aacctatttg tcttgacatc aactctgtta     1980

accttatgtc atcatttctt agagtctttg atatacaaat aaaattttct ttgtatttta     2040

aaaaaaaaaa aaaaa                                                      2055


<210>  2449
<211>  2564
<212>  DNA
<213>  homo sapiens

<400>  2449
gagcggtcac gtgtgagggg cggcccgagg tcacgtgacg gagcgccgga gcggagggag       60

ccggggctgg gagttctcct gagggaagag gagtggagta ggggggacgc ggcggcggcg      120

ttgacaatga gttttcttgg aggctttttt ggtccaattt gtgagatcga tattgttctt      180

aatgatgggg aaaccaggaa aatggcagaa atgaaaactg aagatggcaa agtagaaaaa      240

cactatctct tctatgacgg agaatccgtt tcaggaaagg taaacctagc ctttaagcaa      300

cctggaaaga ggctagaaca ccaaggaatt agaattgaat ttgtaggtca aattgaactt      360

ttcaatgaca agagtaatac tcatgaattt gtaaacctag tgaaagaact agccttacct      420

ggagaactga ctcagagcag aagttatgat tttgaattta tgcaagttga aaagccatat      480

gaatcttaca tcggtgccaa tgtccgcttg aggtattttc ttaaagtgac aatagtgaga      540

agactgacag atttggtaaa agagtatgat cttattgttc accagcttgc cacctatcct      600

gatgttaaca actctattaa gatggaagtg ggcattgaag attgtctaca tatagaattt      660

gaatataata aatcaaagta tcatttaaag gatgtgattg ttggaaaaat ttacttctta      720

ttagtaagaa taaaaataca acatatggag ttacagctga tcaaaaaaga gatcacagga      780

attggaccca gtaccacaac agaaacagaa acaatcgcca aatatgaaat aatggatggt      840

gcaccagtaa aaggagataa ttttatggag aaaagctcct gaaaaactga ggaaacagag      900

aacaaacttt caccagcgat ttgaatctcc agaatcacag gcatctgccg aacagcctga      960

aatgtgaact gaacaggaga aaaaaagaaa agcaaaaaac tcctgtaacc cttgagatta     1020

agttcagcag gttaaagatg gttgcagctg gagggggcgg aaaaaggcca aaactccata     1080

tatgttagtc ttcctttatc ttacagcgca gcatttattt tatgatataa tgaaatgttc     1140

gttcatgtat atacattttt aaaagtgctt tctttgaaac actggaactt tgttaagctg     1200

cctttttttt tttaacttcc tactttgatg ataagcactc agatatatat cagcgtaaac     1260

atgaaaaatt ttcatgtgag taggctggta tttgtaattt tgctttcttt ctgcataatg     1320

ttgattataa atcctctctt ttcaggctaa tgattacctc ttattctcta catgcaaaaa     1380

attaaatatt ttgtgttcaa ataaaattag aaaacctgag tggcctcttg tgtcctgcag     1440

agatttaaaa catggcatct caatattttt gagaactaca tttgttttta acatatgtgt     1500

ttgagaaaag catatggagt gtttcaccgc aggcacttct gagtaccatt ccatggcttc     1560

cagaatttta tcctctttga ggtcttctgt gctatgaata ttagatttct ttccccaagg     1620

gattatgtgg caggtcatta tggccttctt ttttttggcc atattaagta acagttttgc     1680

tatattccag tagtaccgtt gtgtgttttc tgcaatgtgg agttgactta gcttggcatt     1740

ttagatttgt taaaactatt ttttccataa atactttgaa acatatttat atatttcaat     1800

ttaaggaatc tttttgccat gtgtatgcaa atattatttt cttcatacat tcattttctt     1860

ttcaggggaa aattttggga tgggggactc aggaggacct gtgaagcatg tagttatcta     1920

gatctgggta atttcatgtt tattaaactc gaactttggc tagttaaact catattgaaa     1980

cttcatctag tctcttaatt ttttaacact aaattcaagt catttgtttt aagtctctaa     2040

aaaagaagat tgcagtcatc cattcatatg catggggtct gatcgcaaat acactaaatg     2100

tggagtgtag gaaccaaaat gaaacctgct gtatggaaac tactttcact tatggttcat     2160

tggtttttgt accaatattt tttatgcact tcagtgcaag tcttgtcagt taaccttact     2220

ttatgagtaa gctaaataac ccaaattaca tttctttaaa cctgttttac tactatggca     2280

ctttgataaa atggtcagga accaacttta ctggcaaaag ggtccatgta ccaccatgtg     2340

ctggagcatc tgttctacat gtggatatct atgaatggta atgttttcct tcatgtaagt     2400

gcctattcag agtttcagaa ttttaaaatg ccaaatattt tcatggtcat ttgcatgtag     2460

taagccagaa aatattcaaa gagattttga aaaccaattg tatttaacca gcctcaaatt     2520

gtgcaaccat gatgtataat aaagaatttg aaacagaaaa aaaa                      2564


<210>  2450
<211>  4459
<212>  DNA
<213>  homo sapiens

<400>  2450
cctagacaaa ggggccggcg cggcggagca gactggtgca gcctgggccg cgcgctcaga       60

gcgctgggcg tctgggcagc tgagtgggca gagctgaccc ggtgcgggtg ggagtcaggg      120

cgcccggaaa acccggctct gggtagcaga ccccgcccgg gctggctcgg cgccgggcct      180

tcgggcttcc actcagtctt tgaccctcgg tcctcgctca gcggcccggc aggccgcaca      240

actgtaaccg ctgccccggc cgccgcccgc tccttctcgg tccggcgggc acagagcgca      300

gcgcggcggg gccggcggca tggctgtgtc ctggaggagc tggctcgcca acgaaggggt      360

taaacacctc tgcctgttca tctggctctc catgaatgtc ctgcttttct ggaaaacctt      420

cttgctgtat aaccaagggc cagagtatca ctacctccac cagatgttgg ggctaggatt      480

gtgtctaagc agagcctcag catctgttct taacctcaac tgcagcctta tccttttacc      540

catgtgccga acactcttgg cttacctccg aggatcacag aaggttccaa gcaggagaac      600

caggagattg ttggataaaa gcagaacatt ccatattacc tgtggtgtta ctatctgtat      660

tttctcaggc gtgcatgtgg ctgcccatct ggtgaatgcc ctcaacttct cagtgaatta      720

cagtgaagac tttgttgaac tgaatgcagc aagataccga gatgaggatc ctagaaaact      780

tctcttcaca actgttcctg gcctgacagg ggtctgcatg gtggtggtgc tattcctcat      840

gatcacagcc tctacatatg caataagagt ttctaactat gatatcttct ggtatactca      900

taacctcttc tttgtcttct acatgctgct gacgttgcat gtttcaggag ggctgctgaa      960

gtatcaaact aatttagata cccaccctcc cggctgcatc agtcttaacc gaaccagctc     1020

tcagaatatt tccttaccag agtatttctc agaacatttt catgaacctt tccctgaagg     1080

attttcaaaa ccggcagagt ttacccagca caaatttgtg aagatttgta tggaagagcc     1140

cagattccaa gctaattttc cacagacttg gctttggatt tctggacctt tgtgcctgta     1200

ctgtgccgaa agactttaca ggtatatccg gagcaataag ccagtcacca tcatttcggt     1260

cataagtcat ccctcagatg tcatggaaat ccgaatggtc aaagaaaatt ttaaagcaag     1320

acctggtcag tatattactc tacattgtcc cagtgtatct gcattagaaa atcatccatt     1380

taccctcaca atgtgtccaa ctgaaaccaa agcaacattt ggggttcatc ttaaaatagt     1440

aggagactgg acagaacgat ttcgagattt actactgcct ccatctagtc aagactccga     1500

aattctgccc ttcattcaat ctagaaatta tcccaagctg tatattgatg gtccttttgg     1560

aagtccattt gaggaatcac tgaactatga ggtcagcctc tgcgtggctg gaggcattgg     1620

agtaactcca tttgcatcaa tactcaacac cctgttggat gactggaaac catacaagct     1680

tagaagacta tactttattt gggtatgcag agatatccag tccttccgtt ggtttgcaga     1740

tttactctgt atgttgcata acaagttttg gcaagagaac agacctgact atgtcaacat     1800

ccagctgtac ctcagtcaaa cagatgggat acagaagata attggagaaa aatatcatgc     1860

actgaattca agactgttta taggacgtcc tcggtggaaa cttttgtttg atgaaatagc     1920

aaaatataac agaggaaaaa cagttggtgt tttctgttgt ggacccaatt cactatccaa     1980

gactcttcat aaactgagta accagaacaa ctcatatggg acaagatttg aatacaataa     2040

agagtctttc agctgaaaac ttttgccatg aagcaggact ctaaagaagg aatgagtgca     2100

atttctaaga ctttgaaact cagcggaatc aatcagctgt gttatgccaa agaatagtaa     2160

ggttttctta tttatgatta tttaaaatgg aaatgtgaga atgtggcaag atgaccgtca     2220

cattacatgt ttaatctgga aaccaaagag accctgaaga atatttgatg tgatgattca     2280

cttttcagtt ctcaaattaa aagaaaactg ttagatgcac actgttgatt ttcatggtgg     2340

attcaagaac tccctagtga ggagctgaac ttgctcaatc taaggctgat tgtcgtgttc     2400

ctctttaaat tgtttttggt tgaacaaatg caagattgaa caaaattaaa aattcattga     2460

agctgaaatt ccattttctg tgttgtgtat aaacagagta gctttaattt gcaagcactc     2520

caggcaaata tattagatgt ttgaaaacac agcacaagac tctgtattga tacgggtact     2580

ttgtgtcaat atctaatcgt ctccactact tatgctaata cctctatttg atatctgaag     2640

actatatgct aactgaacct tcctcaaatg ttgttatagt atctattttt atatattttt     2700

ttctttttat tcctctctct agggaaatat gccttccctt agcatgcatt agacataatg     2760

atttaatagg tccctttcat cttcatttaa atctatcact attgcatggt aatgaaaata     2820

ttcctactat aaattataaa gggatatata tatatggata tatatatgta tatacacata     2880

tatatataca cacacacaca catatatata tatatatata tatatacaca tatactaata     2940

acttttccct tttttcagca tttttgtctc tattattatt attgtttttt tcccaggtag     3000

ggtttgtctt aggctgtagc ctctaaggat agttagttaa tttgcacttt gagaccaaag     3060

gacatcatgt gtgtcagtag ggactgaata taagatttat ctcctttgcc acacattggt     3120

ttatgatgga gacattgaaa gtctagtcat attcctgaac agtaaaacct gtattttacc     3180

ttttaagtaa gaggaaatat gatattctta ttcaaactta agtttagaat ccagaatatt     3240

actgtcgcac tttttggtat cctgagtttc catagggaac tattgggttt aaagtcaccg     3300

ttggaactac actgtgtgat cttataaact tatgttccct ggctatcata ttcttggctc     3360

agaacaatat ttcccattac tatcttaaga attaaggcat tcatggctca cgcctgtaat     3420

cccggcactt tgggaggcca aggcaggtgg atcacgaggt cagagttcaa gaccagcctg     3480

accaagttgg tgaaacccca tcgctactaa aaatacaaat attaggcggg tgtggtggcg     3540

ggtgcctata atcccaacta ctcgggagac tgaggcaaag aatcgcttga acccggtggg     3600

cggaggttgc agtgagccaa gattgcacca ctgcactcca gcctgggtga cagagcaaga     3660

ttccatctca aaaaaaaaaa aaaaaaaaaa aaaaaagaat taaagcattc atacagttta     3720

gtgattttgt ttagtagtcg gctatcaatt gctatcaaat ataacactgc tgaaatcagc     3780

agtgtgactt accttgccat tgttaaaatg ttacataaaa cataacatga tagatgctaa     3840

ggcctttttt tgctataatt caccaatagc aatcaagcat gctaacccat actgaatgat     3900

atttacttgt agatatttct tcctttcctt gaaattctcc tttctatgga aagaagatga     3960

acccaaaaaa gtgataggaa atgtggaatg ctcatgcaga tttagctctg aaggcatatt     4020

taataactag tatgtcttga caacagtctt tagattaaaa agaattttca tggaaacatt     4080

taacagaaag aactagtaaa aagacacttt gagttagtcc aggcttaatg tgcaatactg     4140

actctatact gatcataatt tatttatgcg atcatattaa tagacctaat ttcattaaaa     4200

caggtagaag atttttcaaa agaaagatga tgtttcaaag ctggtctgcc attctagatg     4260

agcctccttg cttatttaag ttccagtagg tgttcaaatg ttaaatgtta aacataggtc     4320

atctttgctt ctgcagggct tcatcttgca tgtttaagag aactttgttt tattttgagg     4380

gattatttct ctggggatca ttcttataat acaagcctta aatcactaat tttagtagca     4440

ataaatgtta aaattgaaa                                                  4459


<210>  2451
<211>  2766
<212>  DNA
<213>  homo sapiens

<400>  2451
gtcacgtgtc ccccccgcgg ggggcggccc ttgagggcgg cgcttccggt cggcggagcc       60

tggtggccgc agcggcggtg gcgacgacgg ccgagacgtg gggatggcgg gcgccgggag      120

cgaagcccgg ttcgccgggc tgtcgctggt gcagctcaac gagctgctgg aggacgaggg      180

ccagctgacg gagatggtgc agaagatgga ggagacacag aatgttcagc ttaacaaaga      240

aatgacactt gccagcaacc ggagcctggc agaaggaaac cttttgtacc agccccagct      300

ggacacgttg aaagcacgct tgacccagaa ataccaggaa ctccaggttc tctttgaagc      360

ctatcagata aagaagacca aattagacag acagtctagc agtgcttcct tggagaccct      420

gttagcactt cttcaggcag aaggggccaa gattgaggaa gacactgaga acatggcaga      480

gaagtttctg gatggagaac ttcctctgga ttccttcatt gatgtctatc agagcaaacg      540

gaaactggcc cacatgcgac gggtgaaaat cgagaagctc caggagatgg tcctaaaggg      600

gcagagactc ccacaggccc tggccccgct gccccccagg ctgcccgaac tggcacctac      660

cgcccccctt ccctaccctg ccccagaggc cagtgggcct cctgccgttg cacctcggcg      720

catccccccc ccaccacccc cggtgcctgc gggacgctta gccaccccgt ttactgcggc      780

catgagttcg ggacaggccg tgccgtaccc aggattacag tgcccgcccc tgcccccccg      840

cgtgggcctc cccactcagc aaggattctc ttcgcagttc gtgtccccat atccgccacc      900

tctccctcag agacccccgc cccggctccc tccacaccag ccgggtttca tcctccagtg      960

agcgccggcg cggtccttcc cgggagactt cttccacctg gcgtgttgtg ctctgctcac     1020

gggaaggagg ctggaggtcc gctctgtgcc aagggctctg gggccctggg ccagcgtgtc     1080

tgtctgattt tagaactgta ggtcagtggt gagtagtagg agcccaggct ttgggcatca     1140

aggcagttgt gtgtgccggg ttacagcctg acacctgtgc gttgcatcgg tttgcattat     1200

ccgtgtgatt tctaagtatc ttagcgttga tgaactcatg tttgggaaga aataggcctc     1260

tcccccagtc ccatttagaa tcgtggtcct tctgttgcag ctttatttaa tgagcatggt     1320

tcatgatact tattttattt tcgaaagaca gtcctatgtg tctcacccac cggccactgc     1380

agccctggtg agggcgggtg ggcgccggcc ggcctggaag agcgccgtgg ctgggccacc     1440

acctgtggct gcgttgttgc tcactgaatc tgttggggag aggtcaccat agtcaccgcc     1500

tgacctggct gctgctcttg cttcagagcc acaagcaaag tttgcactgg gcccactgcc     1560

gagtccagag gccggagaac ggccactggt gtgggagggg agcgcacgag tgggactttg     1620

cacagcaaat tgtgtcccca gctcctcctc tcccgcctgc ctggagccgg ccctgaaggt     1680

ttctatgaag aaataatccc ccaatatttt tactacgtgt gtgattttcc tgttttatat     1740

tgaaaaaact tttttgacac tcccaagacc attcagggaa attttataaa aaatgcagat     1800

actgtcttga gcagatcgaa atgccgatga agtggatgca atttcctttt gtgcaagcag     1860

tgcacggtgc ccccccctcg ggtgtccgtg ctgtgcctta gcttccccag gtgccgggac     1920

tcacacctgc taggggctgg gcaaggcccc ggctctgctt tctctgaagg gcttgtccaa     1980

gttcattgcc ctgttacagg tggtcaagac gtccggccgc cttgacccag gctaccctta     2040

gccaatatcc tctgcccctg ggtggctggt ggctgggcct cagggtgggc aacgttaggg     2100

gtttggcgaa agcccgcccc atgggattga gggacggggc tgcactccaa ccgtctgcac     2160

ctgctcttcc cccacccctg tgggacctca tcttcacgtg ccatgtgtgc tgaaggccca     2220

gggcccagca gggggcagtg gcacctgttg acggaaaagg ccgaggtgct taccagtgga     2280

ccttctggcc cgcccctccc ctgtcacttg tcgggcatcc agggccccga cctgtgccta     2340

gccgccaggg tgacagaagg cagaactgaa gcggggtctg ggccacgggc caggccactg     2400

ccttttgtcc tcagtgaccg tacattcctg ctctcggact tgaactctac tgtaactgtt     2460

ttcttaaagg aaatgaagct gtacaggacg attcactgcc atgccagtca ggcgggcttg     2520

ccatgttctg tgaatctcga gtgagcggtg ccacccgccc ccatacctcc gccaccggcc     2580

gctgtcgggg atgccacagc ctgccacggt cgcagccaga cgtgagcttg gcattgaagt     2640

tgcaaagcgg cccctggccg ggctcgccgt cgctgtccag ggccgtgtcc ggtgctgtgg     2700

ctgtaaagct gtaggaccct ttttaataaa tagagaatta ttaataacaa aaaaaaaaaa     2760

aaaaaa                                                                2766


<210>  2452
<211>  6913
<212>  DNA
<213>  homo sapiens

<400>  2452
aatattttgt gtgagagcga gcggtgcatt tgcatgttgc ggagtgatta gtgggtttga       60

aaagggaacc gtggctcggc ctcatttccc gctctggttc aggcgcagga ggaagtgttt      120

tgctggagga tgatgacaga ggaatctgag aattgctctc acacaccaac ccagcaacat      180

ccgtggagaa aactctcacc agcaactcct ttaaaacacc gtcatttcaa accattgtgg      240

tcttcaagca acaacagcag cacaaaaaac cccaaccaaa caaaactctt gacagaagct      300

gtgacaacca gaaaggatgc ctcataaagg gggaagactt taactagggg cgcgcagatg      360

tgtgaggcct tttattgtga gagtggacag acatccgaga tttcagagcc ccatattcga      420

gccccgtgga atcccgcggc ccccagccag agccagcatg cagaacagtc acagcggagt      480

gaatcagctc ggtggtgtct ttgtcaacgg gcggccactg ccggactcca cccggcagaa      540

gattgtagag ctagctcaca gcggggcccg gccgtgcgac atttcccgaa ttctgcagac      600

ccatgcagat gcaaaagtcc aagtgctgga caatcaaaac gtgtccaacg gatgtgtgag      660

taaaattctg ggcaggtatt acgagactgg ctccatcaga cccagggcaa tcggtggtag      720

taaaccgaga gtagcgactc cagaagttgt aagcaaaata gcccagtata agcgggagtg      780

cccgtccatc tttgcttggg aaatccgaga cagattactg tccgaggggg tctgtaccaa      840

cgataacata ccaagcgtgt catcaataaa cagagttctt cgcaacctgg ctagcgaaaa      900

gcaacagatg ggcgcagacg gcatgtatga taaactaagg atgttgaacg ggcagaccgg      960

aagctggggc acccgccctg gttggtatcc ggggacttcg gtgccagggc aacctacgca     1020

agatggctgc cagcaacagg aaggaggggg agagaatacc aactccatca gttccaacgg     1080

agaagattca gatgaggctc aaatgcgact tcagctgaag cggaagctgc aaagaaatag     1140

aacatccttt acccaagagc aaattgaggc cctggagaaa gagtttgaga gaacccatta     1200

tccagatgtg tttgcccgag aaagactagc agccaaaata gatctacctg aagcaagaat     1260

acaggtatgg ttttctaatc gaagggccaa atggagaaga gaagaaaaac tgaggaatca     1320

gagaagacag gccagcaaca cacctagtca tattcctatc agcagtagtt tcagcaccag     1380

tgtctaccaa ccaattccac aacccaccac accggtttcc tccttcacat ctggctccat     1440

gttgggccga acagacacag ccctcacaaa cacctacagc gctctgccgc ctatgcccag     1500

cttcaccatg gcaaataacc tgcctatgca acccccagtc cccagccaga cctcctcata     1560

ctcctgcatg ctgcccacca gcccttcggt gaatgggcgg agttatgata cctacacccc     1620

cccacatatg cagacacaca tgaacagtca gccaatgggc acctcgggca ccacttcaac     1680

aggactcatt tcccctggtg tgtcagttcc agttcaagtt cccggaagtg aacctgatat     1740

gtctcaatac tggccaagat tacagtaaaa aaaaaaaaaa aaaaaaaaag gaaaggaaat     1800

attgtgttaa ttcagtcagt gactatgggg acacaacagt tgagctttca ggaaagaaag     1860

aaaaatggct gttagagccg cttcagttct acaattgtgt cctgtattgt accactgggg     1920

aaggaatgga cttgaaacaa ggacctttgt atacagaagg cacgatatca gttggaacaa     1980

atcttcattt tggtatccaa acttttattc attttggtgt attatttgta aatgggcatt     2040

tgtatgttat aatgaaaaaa agaacaatgt agactggatg gatgtttgat ctgtgttggt     2100

catgaagttg tttttttttt ttttaaaaag aaaaccatga tcaacaagct ttgccacgaa     2160

tttaagagtt ttatcaagat atatcgaata cttctaccca tctgttcata gtttatggac     2220

tgatgttcca agtttgtatc attcctttgc atataattaa acctggaaca acatgcacta     2280

gatttatgtc agaaatatct gttggttttc caaaggttgt taacagatga agtttatgtg     2340

caaaaaaggg taagatataa attcaaggaa gaaaaaaagt tgatagctaa aaggtagagt     2400

gtgtcttcga tataatccaa tttgttttat gtcaaaatgt aagtatttgt cttccctaga     2460

aatcctcaga atgatttcta taataaagtt aatttcattt atatttgaca agaatataga     2520

tgttttatac acattttcat gcaatcatac gtttcttttt tggccagcaa aagttaattg     2580

ttcttagata tagttgtatt actgttcacg gtccaatcat tttgtgcatc tagagttcat     2640

tcctaatcaa ttaaaagtgc ttgcaagagt tttaaactta agtgttttga agttgttcac     2700

aactacatat caaaattaac cattgttgat tgtaaaaaac catgccaaag cctttgtatt     2760

tcctttatta tacagttttc tttttaacct tatagtgtgg tgttacaaat tttatttcca     2820

tgttagatca acattctaaa ccaatggtta ctttcacaca cactctgttt tacatcctga     2880

tgatccttaa aaaataatcc ttatagatac cataaatcaa aaacgtgtta gaaaaaaatt     2940

ccacttacag cagggtgtag atctgtgccc atttataccc acaacatata tacaaaatgg     3000

taacatttcc cagttagcca tttaattcta aagctcaaag tctagaaata atttaaaaat     3060

gcaacaagcg attagctagg aattgttttt tgaattagga ctggcatttt caatctgggc     3120

agatttccat tgtcagccta tttcaacaat gatttcactg aagtatattc aaaagtagat     3180

ttcttaaagg agactttctg aaagctgttg cctttttcaa ataggccctc tcccttttct     3240

gtctccctcc cctttgcaca agaggcatca tttcccattg aaccactaca gctgttccca     3300

tttgaatctt gctttctgtg cggttgtgga tggttggagg gtggaggggg gatgttgcat     3360

gtcaaggaat aatgagcaca gacacatcaa cagacaacaa caaagcagac tgtgactggc     3420

cggtgggaat taaaggcctt cagtcattgg cagcttaagc caaacattcc caaatctatg     3480

aagcagggcc cattgttggt cagttgttat ttgcaatgaa gcacagttct gatcatgttt     3540

aaagtggagg cacgcagggc aggagtgctt gagcccaagc aaaggatgga aaaaaataag     3600

cctttgttgg gtaaaaaagg actgtctgag actttcattt gttctgtgca acatataagt     3660

caatacagat aagtcttcct ctgcaaactt cactaaaaag cctgggggtt ctggcagtct     3720

agattaaaat gcttgcacat gcagaaacct ctggggacaa agacacactt ccactgaatt     3780

atactctgct ttaaaaaaat ccccaaaagc aaatgatcag aaatgtagaa attaatggaa     3840

ggatttaaac atgaccttct cgttcaatat ctactgtttt ttagttaagg aattacttgt     3900

gaacagataa ttgagattca ttgctccggc atgaaatata ctaataattt tattccacca     3960

gagttgctgc acatttggag acaccttcct aagttgcagt ttttgtatgt gtgcatgtag     4020

ttttgttcag tgtcagcctg cactgcacag cagcacattt ctgcagggga gtgagcacac     4080

atacgcactg ttggtacaat tgccggtgca gacatttcta cctcctgaca ttttgcagcc     4140

tacattccct gagggctgtg tgctgaggga actgtcagag aagggctatg tgggagtgca     4200

tgccacagct gctggctggc ttacttcttc cttctcgctg gctgtaattt ccaccacggt     4260

caggcagcca gttccggccc acggttctgt tgtgtagaca gcagagactt tggagacccg     4320

gatgtcgcac gccaggtgca agaggtggga atgggagaaa aggagtgacg tgggagcgga     4380

gggtctgtat gtgtgcactt gggcacgtat atgtgtgctc tgaaggtcag gattgccagg     4440

gcaaagtagc acagtctggt atagtctgaa gaagcggctg ctcagctgca gaagccctct     4500

ggtccggcag gatgggaacg gctgccttgc cttctgccca caccctaggg acatgagctg     4560

tccttccaaa cagagctcca ggcactctct tggggacagc atggcaggct ctgtgtggta     4620

gcagtgcctg ggagttggcc ttttactcat tgttgaaata atttttgttt attatttatt     4680

taacgataca tatatttata tatttatcaa tggggtatct gcagggatgt tttgacacca     4740

tcttccagga tggagattat ttgtgaagac ttcagtagaa tcccaggact aaacgtctaa     4800

attttttctc caaacttgac tgacttggga aaaccaggtg aatagaataa gagctgaatg     4860

ttttaagtaa taaacgttca aactgctcta agtaaaaaaa tgcattttac tgcaatgaat     4920

ttctagaata tttttccccc aaagctatgc ctcctaaccc ttaaatggtg aacaactggt     4980

ttcttgctac agctcactgc catttcttct tactatcatc actaggtttc ctaagattca     5040

ctcatacagt attatttgaa gattcagctt tgttctgtga atgtcatctt aggattgtgt     5100

ctatattctt ttgcttattt ctttttactc tgggcctctc atactagtaa gattttaaaa     5160

agccttttct tctctgtatg tttggctcac caaggcgaaa tatatattct tctctttttc     5220

atttctcaag aataaacctc atctgctttt ttgtttttct gtgttttggc ttggtactga     5280

atgactcaac tgctcggttt taaagttcaa agtgtaagta cttagggtta gtactgctta     5340

tttcaataat gttgacggtg actatctttg gaaagcagta acatgctgtc ttagaaatga     5400

cattaataat gggcttaaac aaatgaatag gggggtcccc ccactctcct tttgtatgcc     5460

tatgtgtgtc tgatttgtta aaagatggac agggaattga ttgcagagtg tcgcttcctt     5520

ctaaagtagt tttattttgt ctactgttag tatttaaaga tcctggaggt ggacataagg     5580

aataaatgga agagaaaagt agatattgta tggtggctac taaaaggaaa ttcaaaaagt     5640

cttagaaccc gagcacctga gcaaactgca gtagtcaaaa tatttatctc atgttaaaga     5700

aaggcaaatc tagtgtaaga aatgagtacc atatagggtt ttgaagttca tatactagaa     5760

acacttaaaa gatatcattt cagatattac gtttggcatt gttcttaagt atttatatct     5820

ttgagtcaag ctgataatta aaaaaaatct gttaatggag tgtatatttc ataatgtatc     5880

aaaatggtgt ctatacctaa ggtagcatta ttgaagagag atatgtttat gtagtaagtt     5940

attaacataa tgagtaacaa ataatgtttc cagaagaaag gaaaacacat tttcagagtg     6000

cgtttttatc agaggaagac aaaaatacac acccctctcc agtagcttat ttttacaaag     6060

ccggcccagt gaattagaaa aacaaagcac ttggatatga tttttggaaa gcccaggtac     6120

acttattatt caaaatgcac ttttactgag tttgaaaagt ttcttttata tttaaaataa     6180

gggttcaaat atgcatattc aatttttata gtagttatct atttgcaaag catatattaa     6240

ctagtaattg gctgttaatt ttatagacat ggtagccagg gaagtatatc aatgacctat     6300

taagtatttt gacaagcaat ttacatatct gatgacctcg tatctctttt tcagcaagtc     6360

aaatgctatg taattgttcc attgtgtgtt gtataaaatg aatcaacacg gtaagaaaaa     6420

ggttagagtt attaaaataa taaactgact aaaatactca tttgaattta ttcagaatgt     6480

tcataatgct ttcaaaggac atagcagagc ttttgtggag tatccgcaca acattattta     6540

ttatctatgg actaaatcaa ttttttgaag ttgctttaaa atttaaaagc acctttgctt     6600

aatataaagc cctttaattt taactgacag atcaattctg aaactttatt ttgaaaagaa     6660

aatggggaag aatctgtgtc tttagaatta aaagaaatga aaaaaataaa cccgacattc     6720

taaaaaaata gaataagaaa cctgattttt agtactaatg aaatagcggg tgacaaaata     6780

gttgtctttt tgattttgat cacaaaaaat aaactggtag tgacaggata tgatggagag     6840

atttgacatc ctggcaaatc actgtcattg attcaattat tctaattctg aataaaagct     6900

gtatacagta aaa                                                        6913


<210>  2453
<211>  7292
<212>  DNA
<213>  homo sapiens

<400>  2453
ctctgcgctg cccggtgggg cggggaaaga agccctgagc cgggatctgg cactcccagg       60

actcccggcc ggggtagctc ttcactcctc agcgcgacgt cgtgtcgagt tcccaaaaag      120

ctccgcaggg gctgtaggga ggcatacaag aattaaattc tgaataagtc tgcaggtagg      180

atggacagtt attttaaagc agctgtcagt gacttggaca aactccttga tgattttgaa      240

cagaacccag atgaacaaga ttatctccaa gatgtacaaa atgcatatga ttctaaccac      300

tgctcagttt cttcagagtt ggcttcctca cagcgaactt cattgctccc aaaagaccaa      360

gagtgcgtta atagttgtgc ctcatcagaa acaagctatg gaacaaatga gagttccctg      420

aatgaaaaaa cactcaaggg acttacttct atacaaaatg aaaaaaatgt aacaggactt      480

gatcttcttt cttctgtgga tggtggtact tcagatgaaa tccagccgtt atatatggga      540

cgatgtagta aacctatctg tgatctgata agtgacatgg gtaacttagt tcatgcaacc      600

aatagtgaag aagatattaa aaaattattg ccagatgatt ttaagtctaa tgcagattcc      660

ttgattggat tggatttatc ttcagtgtca gatactccct gtgtttcttc aacagaccat      720

gatagtgata ctgtcagaga acaacagaat gatatcagtt ctgaattaca aaatagagaa      780

atcggaggaa tcaaagaatt gggtataaaa gtagatacaa cactttcaga ttcctataat      840

tacagtggaa cagaaaattt aaaagataaa aagatcttta atcagttaga atcaattgtt      900

gattttaaca tgtcatctgc tttgactcga caaagttcca aaatgtttca tgccaaagac      960

aagctacaac acaagagcca gccatgtgga ttactaaaag atgttggctt agtaaaagag     1020

gaagtagatg tggcagtcat aactgccgca gaatgtttaa aagaagaggg caagacaagt     1080

gctttgacct gcagccttcc gaaaaatgaa gatttatgct taaatgattc aaattcaaga     1140

gatgaaaatt tcaaattacc tgacttttcc tttcaggaag ataagactgt tataaaacaa     1200

tctgcacaag aagactcaaa aagtttagac cttaaggata atgatgtaat ccaagattcc     1260

tcttcagctt tacatgtttc cagtaaagat gtgccgtcct cattgtcctg tcttcctgcg     1320

tctgggtcta tgtgtggatc attaattgaa agtaaagcac ggggtgattt tttacctcag     1380

catgaacata aagataatat acaagatgca gtgactatac atgaagaaat acagaacagt     1440

gttgttctag gtggggaacc attcaaagag aatgatcttt tgaaacagga aaaatgtaaa     1500

agcatactcc ttcagtcatt aattgaaggg atggaagaca gaaagataga tcctgaccag     1560

acagtaatca gagctgagtc tttggatggt ggtgacacca gttctacagt tgtagaatct     1620

caagaggggc tttctggcac tcatgtccca gagtcttctg attgttgtga aggttttatt     1680

aatacttttt caagcaatga tatggatggg caagacttag attactttaa tattgatgaa     1740

ggcgcaaaaa gtggcccact aattagtgat gctgaacttg atgcctttct gacagaacag     1800

tatcttcaga ccactaacat aaagtctttt gaagaaaatg taaatgactc taaatcgcaa     1860

atgaatcaga tagatatgaa aggcttagat gatggaaaca tcaataatat atatttcaat     1920

gcagaagcag gagctattgg ggaaagtcat ggtattaata taatttgtga aacagttgat     1980

aaacaaaata caatagaaaa tggcctttct ttaggagaaa aaagcactat tccagttcaa     2040

caagggttac ctaccagtaa gtctgagatt acaaatcaat tatcagtctc tgatattaac     2100

agtcaatctg ttggaggggc cagacctaag caattgttta gccttccatc aagaacaagg     2160

agttcaaagg acctgaataa gccagatgtt ccagatacaa tagaaagtga acccagcaca     2220

gcagataccg ttgttccaat cacttgtgct atagattcta cagctgatcc acaggttagc     2280

ttcaactcta attacattga tatagaaagt aattctgaag gtggatctag tttcgtaact     2340

gcaaatgaag attctgtacc tgaaaacact tgcaaagaag gcttggtttt gggccagaaa     2400

cagcctactt gggttcctga ttcagaagct ccaaactgta tgaactgcca agtcaaattt     2460

acttttacca aacggcgaca ccattgccga gcatgtggga aagtattttg tggtgtctgt     2520

tgtaatagga agtgtaaact gcaatatcta gaaaaggaag caagagtatg tgtagtctgc     2580

tatgaaacta ttagtaaagc tcaggcattt gaaaggatga tgagtccaac tggttctaat     2640

cttaagtcta atcattctga tgaatgtact actgtccagc ctcctcagga gaaccaaaca     2700

tccagtatac cttcaccagc aactttgcca gtctcagcac ttaaacaacc aggtgttgaa     2760

ggactatgtt ccaaagaaca gaagagagta tggtttgcag atggtatatt gcccaatggt     2820

gaagttgcag atacaacaaa attatcatct ggaagtaaaa gatgttctga agactttagt     2880

cctctctcac ctgatgtgcc tatgacagta aacacagtgg atcattccca ttctactaca     2940

gtggaaaagc caaacaatga gacaggagat attacaagaa atgagataat tcagagtcct     3000

atttctcagg ttccatcagt ggaaaaattg tctatgaaca caggaaatga ggggttacct     3060

acttctggtt catttacact agatgatgat gtttttgcag aaactgaaga accatctagt     3120

cctactggtg tcttagttaa cagcaattta cctattgcta gtatttcaga ttataggtta     3180

ctgtgtgata ttaacaagta tgtctgcaat aagattagtc ttctacctaa tgatgaggac     3240

agtttgcccc cacttctggt tgcatctgga gaaaagggat cagtgcctgt agtagaagaa     3300

catccatctc atgagcagat cattttgctt cttgaaggtg aaggctttca tcctgttaca     3360

tttgtcctaa atgctaatct actcgtgaat gtcaaattca tattttattc ctcagacaaa     3420

tattggtact tttcaaccaa tggattgcat ggcttgggac aggcagaaat tattattcta     3480

ttgttatgtt tgccaaatga agatactatt cctaaggaca tcttcagact atttatcacc     3540

atatataagg atgctctaaa aggaaaatac atagaaaact tggacaatat tacctttact     3600

gagagttttc tcagtagcaa ggatcacgga ggattcctgt ttattacacc tacttttcag     3660

aaacttgatg atctctcatt accaagtaat ccttttcttt gtggaattct tatccagaag     3720

cttgagattc cctgggcaaa ggtttttcct atgcgtttaa tgttgagatt gggtgcagaa     3780

tataaagcat atcctgctcc tctaacaagc atcagaggcc gaaaacctct ttttggagaa     3840

ataggacaca ctattatgaa cttacttgtt gaccttcgaa attaccagta taccttgcat     3900

aatatagatc aactgttgat tcatatggaa atgggaaaaa gctgcataaa aataccacgg     3960

aaaaagtaca gtgatgtaat gaaagtacta aattcttcca atgagcatgt cattagcatt     4020

ggagcaagtt tcagtacaga agcagattct catctagtct gtatacagaa tgatggaatt     4080

tatgaaacac aggccaacag tgccactggc catcctagaa aagtgacagg tgcaagtttt     4140

gtggtattca atggagctct aaaaacatct tcaggatttc ttgctaagtc cagcatagtt     4200

gaagatggct taatggtaca aataactcca gagaccatga atggcttgcg gctagcttta     4260

cgagaacaga aagactttaa aattacatgt gggaaagttg atgcagtaga cctgagagaa     4320

tacgtggata tctgctgggt agatgctgaa gaaaaaggaa acaaaggagt tatcagttca     4380

gtggatggaa tatcattaca aggatttcca agtgaaaaaa taaaactgga agcagatttt     4440

gaaaccgatg agaagattgt aaaatgtacc gaggtgttct actttctaaa ggaccaggat     4500

ttatctattt tatcaacttc ttatcagttt gcaaaagaaa tagccatggc ttgtagtgct     4560

gcgctgtgcc ctcacctgaa aactctaaaa agtaatggga tgaataaaat tggactcaga     4620

gtttccattg acactgatat ggttgaattt caggcaggat ctgaaggcca acttctgcct     4680

cagcattatc taaatgatct tgatagtgct ctgatacctg tgatccatgg tgggacctcc     4740

aactctagtt taccattaga aatagaatta gtgtttttca ttatagaaca tcttttttag     4800

tgaaagaatg tgccatatta catattgcaa cctaatttgt taaaactaac tccagcacta     4860

aagctgaaat gccacaaaca ctaaaagtat aaatatgtct gatttttgaa acacataagc     4920

tttgctcttt aggcaggaat gatcttttca aatcattagc acaatattta aatatctaaa     4980

aatttaagag atccatactt tctgtagctt tacaattaat ttaagtacta aaaagacaag     5040

gatttctttt aagaaattta tagcatttac tgtgttattt aaatgctaag ccaaagtatc     5100

tgcacttagg tatacctctt tatgccaata atgattttaa tgaaggctct tttcagatgt     5160

aaccttatga aggaaatatc tgctttgtgt atatgccagt tagaatactg gtttctaaag     5220

tctgtcaaat tgtatttcag tggcacaaaa accagttttg aggtcttaga cttataattc     5280

tttgaataaa actgataact tatttgtata attggagtgg agacctacct ccataattag     5340

ataaactctt tttggattat aatcagaatt ttgccttttt tcttctcaaa ttattacata     5400

tgtatgtatt atatatccac atatatagtt ttccctgatt aaatggatat taaaataatt     5460

gcgggtgctt caggactttt tgcttctata tttaagtata ttgtttttat agcaagaaca     5520

tattctgaat gttttataaa tctttaataa tttatatgta ggtaatattt ttgtatcaca     5580

atgcattatt tttttcctcc tttccttcca aactatacca ctgtatttac cacttctaag     5640

agtgactgac gacgggccag atgacccttg aagtagtcat tatgtagcaa taaatgaagc     5700

ctgaaacagg tttttttact tccactttaa tccttagaaa tttcttggca acttcgcata     5760

ttttcattga caccagtgta taagtataaa tttaaatgaa ctaattactt ttgcatattt     5820

taaattcttt atatggtagt tattttttat aacaggatat taacataagt taaatcctat     5880

gtatttgaaa ttgttacaga gctttcctct ttacttcaaa cagcaaaaaa gtggggggca     5940

tattgtagtc ctgtcattta agttatgtaa aaaatttaat cattattttg atgctttaaa     6000

cattctcatg tgtaatatat gtttttgtat caaaaacact catatatttc aagaaaaaga     6060

aattatgtta aatagccctg ttttaagaaa aatatttatg aagcatctca acttgaagat     6120

caagtcaaag ttataactca ggatctgagg tctcaagcta ggagagactg agaattttaa     6180

tcagtttggg catatagttt ggactgaatc acatctgtag tacttagcca aagacaattt     6240

ggaggagaat atcagccttc tggaagtagc tacttcctga acaatgtaaa gtgtcgcaga     6300

tattcaataa aatggcaacc tgttataatt tgtgaaattt attgaaatgg tgtaagatga     6360

aaacaattgc atatcaaacc caatttatgt tttctaaata tagtgtatgt attctgccat     6420

gtaagtaatt gaacagtctt aaaataacca aatggtagag ggctgttcca tgatgggaca     6480

gctttggatt tgttttcata aaatctctat attcaataaa aattggaatt atgtgcctga     6540

agtttggagg cacattttga agtattcttt gtagacatat agtatgtttc tgaatgtgtt     6600

tgttacttat ttggtcattg gtacttaatt tgaaatttta attttttaag agaagaaata     6660

gaatggttct ttgtactcag tctgcaatga tctatttttg gcttatgtct tttaatacta     6720

ctctctttct ctgaattttg aaatatgaag taaaatctag cccatttgtt ttatgcagct     6780

attcaacaaa ctttgtgtgt tcgtatactt gctacatgca gagcacttta ccaggtttct     6840

aagcaaaaat ttctaaaaat gattaattgt tctgacagaa ttaggcgtag ttctttatca     6900

acatttatgg attccatgcc acaagtagta tgcgcttaag tgcagagcat gccaagagaa     6960

agagtaggat ttggccctgt aggagcaaag attcaattgt gggaaactac ttgtttctga     7020

aaattgcatg ctaggatatt tacatcatgt tcctgttgaa aacaattcct gattaaaata     7080

caagaataat cttaaaacat caaagagatt ttccagacaa taaggaatgc caagtccaaa     7140

agtaaagaga ataagagaag caagcatgta cccttactct gacaacctta tgagtgaggg     7200

ggacagaaat taaagttcag ggcccatata aggtgatgaa cctaacagga gaccctccac     7260

acaataggct gagactccca aatactttca cc                                   7292


<210>  2454
<211>  7155
<212>  DNA
<213>  homo sapiens

<400>  2454
gggctgggga tcggggggcg ccgagtttga ctagtttggg ggcggctggg cgcttggcgt       60

tcctcccgcc gcccgctgcg ccccgcaagc cgcgcccctg gcgggctaag tgagtcccgc      120

ccgctcccgc ggggacccgc actggaggct gggcggctct cggcgaaagt tggccgctca      180

cagactggca ggcgggcggg cggccgcagc catggagccc cgcagcatgg agtacttctg      240

cgcccaggtg cagcagaagg acgtcggcgg ccggctgcag gtcggccagg agctcctgct      300

ctaccttggc gcccccggcg ccatctcgga cctggaggag gacctgggcc gcctaggcaa      360

gacagtcgac gcgctcaccg gctgggtggg ttcgagcaac taccgggtat cattaatggg      420

attggaaatt ttaagtgcct ttgtggacag attatcaaca cgctttaaat cctatgtagc      480

aatggttatt gtagctttaa tagacagaat gggagatgcc aaagacaagg ttcgagatga      540

agctcagact ctgatattga agttaatgga tcaagtagca ccacctatgt acatttggga      600

gcagttggct tctggtttta aacacaagaa ttttcgatct cgagaaggcg tgtgtctgtg      660

tcttattgaa accttaaaca tttttggggc tcagccacta gtcatcagca aattgatacc      720

acatttgtgt atcctgtttg gagactccaa cagtcaggtg agagatgctg caatattggc      780

tatagtggag atttatagac atgtgggaga aaaagtgagg atggatcttt ataagagagg      840

aattccccct gctagattag aaatgatatt tgccaaattt gatgaagtgc aaagttcagg      900

cggtatgatt ttgagtgtct gcaaagataa aagcttcgat gatgaagaat cagtggatgg      960

aaataggcca tcatcagctg catcagcctt caaggttcct gcacctaaaa catccggaaa     1020

tcctgccaac agtgcaagga agcctggttc agcaggtggc cctaaggttg gagcaggtgc     1080

ttctaaggaa ggaggtgctg gagcagttga tgaagatgat tttataaaag cttttacaga     1140

tgtcccttct attcagattt attctagtcg agaactcgaa gaaacattaa ataaaatcag     1200

ggaaattttg tcagatgata aacatgactg ggatcagcgt gccaatgcac tgaagaaaat     1260

tcgatcactg cttgttgctg gagctgcaca gtatgattgc ttttttcaac atttacgatt     1320

gttggatgga gcacttaaac tttcagctaa ggatcttaga tcccaggtgg ttagagaagc     1380

ttgtattact gtagcccacc tttcaacagt tttgggaaac aagtttgatc atggcgctga     1440

agccattgta cctacacttt ttaatctcgt ccccaatagt gcaaaagtca tggcaacttc     1500

tggatgtgca gcaatcagat ttatcattcg gcatactcat gtacccagac ttataccttt     1560

aataacaagc aattgcacat caaaatcagt tcccgtgagg agacgttcat ttgaattttt     1620

agatttattg ttgcaagagt ggcagactca ttcattggaa agacatgcag ccgtcttggt     1680

tgaaactatt aaaaagggaa ttcatgatgc tgacgctgag gccagagtgg aggcaagaaa     1740

gacatacatg ggtcttagaa accactttcc tggtgaagct gaaacattat ataattccct     1800

tgagccatct tatcagaaga gtcttcaaac ttacttaaag agttctggca gtgtagcatc     1860

tcttccacaa tcagacaggt cctcatccag ctcacaggaa agtctcaatc gccctttttc     1920

ttccaaatgg tctacagcaa atccatcaac tgtggctgga agagtatcag caggcagcag     1980

caaagccagt tcccttccag gaagcctgca gcgttcacga agtgacattg atgtgaatgc     2040

tgctgcaggt gccaaggcac atcatgctgc tggacagtct gtgcgaagcg ggcgcttagg     2100

tgcaggtgcc ctgaatgcag gttcctatgc gtcactagag gatacttctg acaagctgga     2160

tggaacagca tctgaagatg gccgggtgag agcaaaactt tcagcaccac ttgctggcat     2220

gggaaatgcc aaggcagatt ctagaggaag aagtcgaaca aaaatggtgt ctcaatcaca     2280

gcctggtagc cggtctgggt ctccaggaag agttctgacc acaacagccc tgtccactgt     2340

gagctctggt gttcaaagag tcctggtcaa ttcagcctca gcacaaaaaa gaagcaagat     2400

accacggagc cagggctgta gcagagaggc tagtccatct aggctttcag tggcccgaag     2460

cagtcgtatt cctcgaccaa gtgtgagtca aggatgcagc cgggaagcta gtcgggagag     2520

cagcagagac acaagtcctg ttcgctcttt tcagcccctc ggtccaggtt atgggatcag     2580

ccaatcaagt cgactgtcgt cttctgttag tgccatgcga gtcctgaaca caggttctga     2640

tgtggaggag gcggtggcag atgccttgct cttaggagac atacggacta agaaaaaacc     2700

agctcgaaga agatatgaat catatggaat gcattcagat gatgacgcca acagcgatgc     2760

atctagtgct tgttcagaac gctcctatag ttctcgaaat ggtagtattc ctacatatat     2820

gaggcagacg gaagatgtgg cagaagtcct caatagatgt gctagttcca attggtcaga     2880

aaggaaagaa ggcctcctag gtctgcagaa cttattaaaa aatcagagaa cactaagtcg     2940

agttgaactg aaaagattat gtgaaatttt cacaagaatg tttgctgacc ctcatggcaa     3000

gagagtattc agcatgtttt tggagactct agtggatttc atacaagtcc acaaagatga     3060

tcttcaagat tggttgtttg tactgctgac acaactacta aaaaaaatgg gtgctgattt     3120

gcttggatct gttcaggcaa aagttcagaa agcccttgat gttacaagag agtcttttcc     3180

aaatgatctt cagttcaata ttctaatgag atttacagtt gatcagaccc agacaccaag     3240

cttaaaggtg aaggttgcta tccttaaata catagaaact ctggccaaac agatggatcc     3300

aggagatttt ataaattcca gtgaaactcg cctagcagtg tctcgggtca tcacttggac     3360

aacagaaccc aaaagttctg atgttcggaa ggcagcacag tcagtgctga tttcattatt     3420

tgaactcaat accccagagt ttacaatgtt attaggagct ttaccaaaaa cttttcagga     3480

tggtgctacc aagcttcttc ataatcacct tcgaaacact ggcaatggaa cccagagttc     3540

catggggagt cctttgacaa gaccaacacc acgatcacca gctaactggt ccagtcctct     3600

tacttctcct accaatacat cacagaatac tttatctcca agtgcatttg attatgacac     3660

agaaaatatg aactctgaag atatttatag ctctcttaga ggtgtcactg aagcaatcca     3720

gaatttcagc ttccgtagcc aagaagatat gaatgagcca ttgaaaaggg attctaaaaa     3780

agatgatggc gattcaatgt gtggtggtcc tgggatgtct gacccaagag caggaggtga     3840

tgctactgac tcaagtcaaa cagctcttga taataaagct tcattgctcc attcaatgcc     3900

tactcactcc tctccacgct ctcgagacta taatccatat aactattcag atagcatcag     3960

tcccttcaac aagtctgccc tcaaggaagc catgtttgat gatgatgctg accagtttcc     4020

tgacgatctt tccctagatc attctgacct agttgcagag ttgttgaagg agctgtctaa     4080

ccataatgag cgtgtagaag aaagaaaaat tgccctctat gaacttatga aactgacaca     4140

ggaagaatct tttagtgttt gggatgaaca cttcaaaaca atattgcttt tattgcttga     4200

aacgcttgga gataaagagc ctacaatcag ggctttggca ttaaaggttt taagagaaat     4260

cctaaggcat caaccagcaa gatttaaaaa ctatgcagaa ttgactgtca tgaaaacatt     4320

ggaagcacat aaagatcctc ataaggaggt ggtgagatct gctgaggaag cggcatcagt     4380

gttggccact tcaattagtc cagagcagtg catcaaagtg ctttgtccta tcattcaaac     4440

tgcagactac ccaattaatc tggctgcaat caaaatgcaa acaaaagtga tagagagagt     4500

gtccaaggaa accctaaacc tgcttttgcc agagattatg ccaggtctaa tacagggtta     4560

tgataattca gagagcagtg ttcggaaagc ttgtgtcttc tgcctggtgg ctgttcatgc     4620

ggtaattggt gatgaactaa aaccacatct cagtcaactt actggcagta aaatgaagct     4680

actgaatctt tacatcaaac gtgcacaaac aggttctgga ggagctgatc ccactactga     4740

tgtttctgga caaagttagt gaagctcatc acagcgaacc aggtctctca aaagaaagga     4800

cagatagacc accctcatca atgaaaggaa gttctcaaac acatcctttg gaacttacta     4860

ttgtttccca gttttagttt tttgtttcgt ttcgttttgt attttctgta acagaggact     4920

atcctcagtc tgcatgtaac ttttatgata gttattccaa attcaagaag aagcagtatt     4980

aacatcaatt gatcgacaca aagtaatttt taatttaatt catcatttca catgtttgta     5040

ctttgtcttc ccattaacct ttgccagtgt tatgattgta taaatttttt taaatgctgg     5100

ttaaacagga atgcttaaag ctttaaaagt ttaacagtct aaaacatttt tgcttttatt     5160

caactgcaga ataatatttt tattgctact ttgagttttg tttcgtatca tgtcctatgc     5220

tagaaatatt taaatgatgt gaaacaaagc aggactaatt tgaactacag ctggactccg     5280

tttgtgtgat ggtgatacat gtcattagtt gcaacttctt tggggtgatc tatagtttga     5340

aaactaaaac ctcaaagaca gatgttacag aatcagccag ttctgtaaaa ctgatattgt     5400

ctattggtta ttgatcttgc catctttatt taaaaccatg tcccttctat gatcccttaa     5460

gaaagctgca ccaaatcatc tgcctgtttt ttcttgatac ttactgaaat agaaggtttt     5520

attgcagggt ttattttggt ttgtttatat ctttgttgtg aatgatgctt ttttgtattt     5580

attaatatca aattcactta tgaataaact tgataatgga aacggacaaa aaaaatcaag     5640

tgcgtgtgtg tccttgaccg tcttctgttt ctcacgtaat aaacaaatta tcgagacatg     5700

ggagtgacca gcaccttttc tttaaatggt ggaacctggt ttccttttac catgaaattg     5760

tcttacttga aaatattgat cctgatgaga gagaagatgg tgccaaggct gtctttgtat     5820

aatgggctca aattctctac ctcttcaggg ctaatacttt taactgagct gctgcctata     5880

gtgtcttttg gaaaactact taaagggtga ttttctgtta ctttttagca aattttttta     5940

atcacctctt gctacaccca ttcttttcat gtgcagccga ctcaaaaatt accagttttg     6000

gtgaaaggct aaattagata atttggaacc aggatactaa tgatttctca tctttacttt     6060

tttttaatcc taatataaag tgaatttgat tgaaaaggca aatagctatt agggaagcag     6120

tttgccattg ttgcagagtt atctgtactt tgtttaactg aaaaaaatgt agaaatatat     6180

gtaaagaatt taagacaaga gtactgaatg gatgatttgt cataggcttt cccctttctt     6240

tctgttctag cagcaggaaa agtttctcta tatcctctcc ctctacctgt aacaattttg     6300

ttttctactg ttaattacat tgtgtattta tagttctatg cttactgttg tgcatatact     6360

ggcaataaaa ctgtacataa cattacttga aaaagttaat aatgtatatc agtttttctg     6420

tctcactgtg taacaagtca ctcagtttta ttttaacttt agacggtctt gtatcagtgg     6480

tggtctcttg aattttgtaa gttcatctga ggagaaaaga tttttcaggt gtagctacca     6540

caatcaaagg tatatagcta catacgcatg tatatattac agcttatctg taagaagaaa     6600

atgcatttta aacacaactc ttctcagtag cattttatga cctttggata tgtttgtaat     6660

catttcgaat caaaatattg atttaatttt gacctctggt ttaagatact gctttaacta     6720

ctgttgacaa ccaagtagag tgacttaagc tgaacagtaa ctaactggaa aattagataa     6780

gcacctggca tctaatggca ggcaggcact caagaaatga attaactaca taatggaaaa     6840

gtatggttta atgtgtccaa atgaaagcta gtagatgtaa acatggaaaa attgtgttta     6900

caattttata atctcagttg ataagactat aagaaagctg attatttaaa tcactatata     6960

caatacaccc ttaatttgtt cattccagaa acatactgag atgtcagcta cttaaaaatg     7020

gtcacaaaaa gctactgttt atatttttcc tcctgctatt ctctcccaaa ttaattatta     7080

ataagtgttg ttcatttact gcactgctga gaactaatta aaattatata ttccagattg     7140

taaaaaaaaa aaaaa                                                      7155


<210>  2455
<211>  1176
<212>  DNA
<213>  homo sapiens

<400>  2455
aatagtgatt aggaaacctt gaagcctgcc caacgatcgt gggcaggagg tggtttctgg       60

tttgttgggg cgtgtgtatg tgtatttggg gggactgaag ggtacgtggg gcgaaacaaa      120

accggccatg gcagcagcgg aggaggagga cgggggcccc gaagggccaa atcgcgagcg      180

gggcggggcg ggcgcgacct tcgaatgtaa tatatgtttg gagactgctc gggaagctgt      240

ggtcagtgtg tgtggccacc tgtactgttg gccatgtctt catcagtggc tggagacacg      300

gccagaacgg caagagtgtc cagtatgtaa agctgggatc agcagagaga aggttgtccc      360

gctttatggg cgagggagcc agaagcccca ggatcccaga ttaaaaactc caccccgccc      420

ccagggccag agaccagctc cggagagcag agggggattc cagccatttg gtgataccgg      480

gggcttccac ttctcatttg gtgttggtgc ttttcccttt ggctttttca ccaccgtctt      540

caatgcccat gagcctttcc gccggggtac aggtgtggat ctgggacagg gtcacccagc      600

ctccagctgg caggattccc tcttcctgtt tctcgccatc ttcttctttt tttggctgct      660

cagtatttga gctatgtctg cttcctgccc acctccagcc agagaagaat cagtattgag      720

ggtccctgct gacccttccg tactcctgga cccccttgac ccctctattt ctgttggcta      780

aggccagccc tggacattgt ccaggaaggc ctggggagga ggagtgaagt ctgtgcatag      840

atgggagagc cttctgctca gaggctcact cagtaacgtt gtttaattct ctgccctggg      900

gaaggaggat ggattgagag aatgtctttc tcctctccta agtctttgct ttccctgatt      960

tcttgatttg atcttcaaag gtgggcaaag ttccctctga ctcttccccc actccccatc     1020

ttactgattt aatttaattt ttcactcccc agagtctaat atggattctg actcttaagt     1080

gcttccgccc cctcactacc tcctttaata caaattcaat aaaaaaggtg aaatataaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                               1176


<210>  2456
<211>  2642
<212>  DNA
<213>  homo sapiens

<400>  2456
gtttctctcc ctgcccccgc gacttcgcgc aagatccggg aaggacaccc gaggcccctg       60

ggagaccctg gggaggtgaa aatcagagag cgaagcgggc cgtggcccct aggcctgacc      120

cctccccgcg gggtaaggcg ggcaccccgc gagcgcaggg gtcctcttac tgctgatggc      180

acccagctct gggcccagac gccgctcacc gtccaccgcc ggtgctgggt aaaatgtcgg      240

ttccaggacc ttaccaggcg gccactgggc cttcctcagc accatccgca cctccatcct      300

atgaagagac agtggctgtt aacagttatt accccacacc tccagctccc atgcctgggc      360

caactacggg gcttgtgacg gggcctgatg ggaagggcat gaatcctcct tcgtattata      420

cccagccagc gcccatcccc aataacaatc caattaccgt gcagacggtc tacgtgcagc      480

accccatcac ctttttggac cgccctatcc aaatgtgttg tccttcctgc aacaagatga      540

tcgtgagtca gctgtcctat aacgccggtg ctctgacctg gctgtcctgc gggagcctgt      600

gcctgctggg gtgcatagcg ggctgctgct tcatcccctt ctgcgtggat gccctgcagg      660

acgtggacca ttactgtccc aactgcagag ctctcctggg cacctacaag cgtttgtagg      720

actcagccag acgtggaggg agccgggtgc cgcaggaagt cctttccacc tctcatccag      780

cttcacgcct ggtggaggtt ctgccctggt ggtctcacct ctccaggggg cccaccttca      840

tgtcttcttt tggggggaat acgtcgcaaa actaacaaat ctccaaaccc cagaaattgc      900

tgcttggagt cgtgcatagg acttgcaaag acattcccct tgagtgtcag ttccacggtt      960

tcctgcctcc ctgagaccct gagtcctgcc atctaactgt gatcattgcc ctatccgaat     1020

atcttcctgt gatctgccat cagtggctct tttttcctgc ttccatgggc ctttctggtg     1080

gcagtctcaa actgagaagc cacagttgcc ttatttttga ggctgttctg cccagagctc     1140

ggctgaacca gcctttagtg cctaccatta tcttatccgt ctcttcccgt ccctgatgac     1200

aaagatcttg ccttacagac tttacaggct tggctttgag attctgtaac tgcagacttc     1260

attagcacac agattcactt taatttctta attttttttt taaatacaag gagggggcta     1320

ttaacaccca gtacagacat atccacaagg tcgtaaatgc atgctagaaa aatagggctg     1380

gatcttatca ctgccctgtc tccccttgtt tctctgtgcc agatcttcag tgcccctttc     1440

catacaggga tttttttctc atagagtaat tatatgaaca gtttttatga cctccttttg     1500

gtctgaaata cttttgaaca gaatttcttt tttttaaaaa aaaacagaga tggggtctta     1560

ctatgttgcc caggctggtg tcgaactcct gggctcaagc gatccttctg ccttggcctc     1620

ccgaagtgct gggattgcag gcataagcta ccatgctggg cctgaacata atttcaagag     1680

gaggatttat aaaaccattt tctgtaatca aatgattggt gtcattttcc catttgccaa     1740

tgtagtctca cttaaaaaaa aaaaaaagaa aaagaaatgg ataatttcat ctactgcctt     1800

tacttggggt taatgtgatt cttaaacacc ttcatcatgg aactctcaga gtggggtccg     1860

ttttggtttc ctggtggtgg gttttgaaag ataagggaaa gcacattttg agcatgtctg     1920

ggtaccatgg tgcggatgct tgggaaccag aactgtttca gaggaatcta aagtctgatt     1980

ttagttttca gagacacagc ttgttgtaaa acatgagaag acatgatttc taggactcaa     2040

gcagcaagcc aggattctag gttggctgct gtgtcatctt tgaagtcaag acaaagctgg     2100

gctcgacctt caagggtcct cgttttgata atacttcaga atagggaact catgtgaata     2160

ctactatgta gaaataaaac ctagaccttg agcgaacatc tgtatattgg ttgaaaacga     2220

tagtggtaac cattgatccc ccttcatttg atgtttggaa aattccagta attatcattt     2280

ttgcaacgaa tatggatacc acatagtact ttggtgttac ctgcttttga aaaataaagt     2340

ctttggttca cccggtgaac tatttatgag ttcttttggt gtgaagaaag ggctcatgtt     2400

gcatttccag ccattgctac aaagaacctt tatttgttca gtaacggtag aaaatccttc     2460

ccgattaaaa acttcagact tgctgaatat cctgcaatgt caagatgacc gatgttgagt     2520

tgggtggatt tgctaacgag tcagatttga acatgaggct attggaaccc aataggcgtc     2580

attgatggcg gcaagccata gctttcaagt tttaataaaa tgcacaaaag agaaaaaaaa     2640

aa                                                                    2642


<210>  2457
<211>  1369
<212>  DNA
<213>  homo sapiens

<400>  2457
cacaacattt ccttgtatgt ggatagcgtg aaagaagctt gtgatcctgc ccccaccctc       60

cccaccgcca cattttttaa agtgtattgt tgcagcatct ggcagtgaga ctgaggatga      120

ggacagcatg gacattccct tggacctttc ttcatccgct ggctcaggca agagaaggag      180

aaggggcaac ctacccaagg agtctgtgca gattcttcgg gattggctgt atgagcaccg      240

ttacaatgcc tatccttcag agcaagaaaa agcgttgctg tcccagcaaa cacacctgtc      300

tacgctacag gtctgtaact ggttcatcaa cgcccgccgc aggctcctcc ctgacatgct      360

gagaaaggat ggcaaagatc caaatcagtt cacaatttcc cgccgtgggg ccaagatttc      420

tgaaacgagc tctgtggagt ccgtgatggg catcaaaaac ttcatgccag ctctagagga      480

gaccccattt cattcctgta cagctgggcc aaacccaacc ctagggaggc cactgtctcc      540

taagccgtca tccccgggat cagttttggc tcgtccatca gtgatctgcc ataccactgt      600

gactgcattg aaagatgtcc ctttctctct ctgccagtcg gtcggtgtgg gacaaaacac      660

agatatacag cagatagcgg ccaaaaactt cacagacacc tctctcatgt acccagagga      720

cacttgtaaa tctggaccaa gtacgaatac acagagtggt cttttcaaca ctcctccccc      780

tactccaccg gacctcaacc aggacttcag tggatttcag cttctagtgg atgttgcact      840

caaacgggct gcagagatgg agcttcaggc aaaacttaca gcttaaccca ttttcaagca      900

aaacagttct cagaaatgtc atgattgccg gggtgaaggc aagagatgaa ttgcattatt      960

ttatatattt tttattaata tttgcacatg ggattgctaa aacagcttcc tgttactgag     1020

atgtcttcaa tggaatacag tcattccaag aactataaac ttaaagctac tgtagaaaca     1080

aagggttttc ttttttaaat gtttcttggt agattattca taatgtgaga tggttcccaa     1140

tatcatgtga tttttttttt cctccccttc cctttttttg ttattttttc agactgtgca     1200

atacttagag aacctatagc atcttctcat tcccatgtgg aacaggatgc ccacatactg     1260

tctaattaat aaattttcca ttttttttca aacaagtatg aatctagttg gttgatgcct     1320

tttttttcat gacataataa agtattttct ttaaaaaaaa aaaaaaaaa                 1369


<210>  2458
<211>  4562
<212>  DNA
<213>  homo sapiens

<400>  2458
ggttggaatt ttggcgggtt cagctgtgaa cgaagaaggc gtcccggcat cggccaagat       60

tctacattgc tcatctgggc atctgagcct ccttcgaagt ttcctgtcac aactgtcctc      120

ttgacagcat ggatgaggag gaagacaatc tgtctctgct gaccgcactg ctggaagaaa      180

atgagtcagc cttggattgt aattcagaag aaaataactt cttgacgcgg gaaaatggcg      240

agcccgacgc atttgatgag ctctttgatg ccgacggcga cggtgaatct tatacagaag      300

aggctgatga tggagaaaca ggagagacaa gagacgaaaa ggaaaatctg gccactctct      360

ttggagatat ggaggactta acagatgaag aagaagttcc cgcatcacag tcaactgaaa      420

atagggtcct ccctgctcct gcccccaggc gagagaaaac gaatgaagag ttgcaagagg      480

aattaaggaa tttgcaagag caaatgaagg ccttacaaga gcagctaaaa gtaacaacaa      540

ttaaacagac agcaagccca gcccgtctgc aaaaatcccc tgtagagaag tctccccggc      600

cacctcttaa ggagaggaga gttcagagaa ttcaggagtc aacatgcttt tctgcggagc      660

ttgatgtccc tgcgctacca agaaccaaga gggtggctcg aacaccaaag gcttcacctc      720

cagatcccaa aagctcatct tcaaggatga caagtgcacc ctcccaaccc ctacagacga      780

tttctcggaa caaacctagt gggataacta gaggtcaaat tgtggggacc ccaggaagtt      840

ctggggaaac gactcaaccc atctgtgtgg aagccttctc tggtctgcgg ctcaggcggc      900

ctcgagtatc ctccacagaa atgaacaaga aaatgaccgg ccgaaaactg atcagactgt      960

ctcagatcaa ggaaaagatg gccagagaga agctggaaga aatagattgg gtgacatttg     1020

gggttatatt gaagaaggtt acgccacaga gtgtgaatag tggaaaaacc ttcagcatat     1080

ggaaactgaa tgatcttcgt gacctgacac aatgtgtgtc cttgttctta tttggagaag     1140

ttcacaaagc gctctggaag acggagcagg ggactgtcgt agggatcctc aatgccaacc     1200

ccatgaagcc caaggatggt tcagaggagg tgtgtttatc tatcgatcat cctcagaagg     1260

tcttaattat gggtgaagct cttgacctgg gaacctgtaa agccaagaag aagaatggag     1320

agccgtgcac gcagactgtg aatttgcgtg actgtgagta ctgtcagtac catgtccagg     1380

ctcagtacaa gaagctcagc gcaaagcgtg cggatctgca gtccaccttc tctggaggac     1440

gaattccaaa gaagtttgcc cgcagaggca ccagcctcaa agaacggctg tgccaagatg     1500

gcttttacta cggaggggtt tcttctgcct cgtatgcagc ttcaattgca gcagctgtgg     1560

ctcctaagaa gaagattcaa accactctga gtaatctggt tgttaagggc acaaacttga     1620

tcatccagga aacacggcaa aaactcggaa taccccagaa gagcctgtct tgctctgagg     1680

agttcaagga actgatggac ctgccgacgt gtggagccag gaacttaaaa caacatttag     1740

ccaaagccac agcttcaggg attatgggga gcccaaaacc agccatcaag tccatctcgg     1800

cctcagcact cttgaagcaa cagaagcagc ggatgttgga gatgaggaga aggaaatcag     1860

aagaaataca gaagcgattt ctgcagagct caagtgaagt tgagagccca gctgtgccat     1920

cttcatcaag acagccccct gctcagcctc cacggacagg atccgagttc cccaggctgg     1980

agggagcccc ggccacaatg acgcccaagc tggggcgagg tgtcttggaa ggagatgatg     2040

ttctctttta tgatgagtca ccaccaccaa gaccaaaact gagtgcttta gcagaagcca     2100

aaaagttagc tgctatcacc aaattaaggg caaaaggcca ggttcttaca aaaacaaacc     2160

caaacagcat taagaagaaa caaaaggacc ctcaggacat cctggaggtg aaggaacgtg     2220

tagaaaaaaa caccatgttt tcttctcaag ctgaggatga attggagcct gccaggaaaa     2280

aaaggagaga acaacttgcc tatctggaat ctgaggaatt tcagaaaatc ctaaaagcaa     2340

aatcaaaaca cacaggcatc ctgaaagagg ccgaggctga gatgcaggag cgctactttg     2400

agccactggt gaaaaaagaa caaatggaag aaaagatgag aaacatcaga gaagtgaagt     2460

gccgtgtcgt gacatgcaag acgtgcgcct atacccactt caagctgctg gagacctgcg     2520

tcagtgagca gcatgaatac cactggcatg atggtgtgaa gaggtttttc aaatgtccct     2580

gtggaaacag aagcatctcc ttggacagac tcccgaacaa gcactgcagt aactgtggcc     2640

tctacaaatg ggaacgggac ggaatgctaa aggaaaagac tggtccaaag ataggaggag     2700

aaactctgtt accaagagga gaagaacatg ctaaatttct gaacagcctt aaataacccg     2760

aacttcagac attttcccac agacttcctg gcctcctgtg actctggaaa gcaaaggatt     2820

ggctgtgtat tgtccattga ttcctgattg acgccgtcaa aaacaaatgc ttgttaagcc     2880

cataagcttt gcctgcttac tttctgccat tgggttggtt tgataccaca tttaacattg     2940

acatttaagt ggaaaaccaa gttatcattg tcttttctaa gctcagtgtg gatgattgca     3000

ttacttcatt cactgaagtt tttgcccaaa aattggaagg taaacagaga gctatgtttc     3060

tgtatctttt ggttatagag tgttcacttc tttatcataa caaaattcta gtgtttatac     3120

gaacacccag aggcaaaaga atttggctta attctcactc caggtaagta gcttaacttc     3180

tgggcttcag ttttctcatc tgtaaaatca ggaagattgg actaagtgat cctgaaatgt     3240

attttttagc actggatttc tacaaataat aaaactttcc catctagata atgatgatca     3300

catagtcttg atgtacggac attaaaagcc agatttcttc attcaattct gttatctctg     3360

ttttactctt tgaaattgat caagccactg aatcactttg catttcagtt tatatatata     3420

gagagaaaga aggtgtctgc tcttacatta ttgtggagcc ctgtgataga aatatgtaaa     3480

atctcatatt attttttttt taattttttt attttttatg acagggtctc actatgtcac     3540

cctggctgga gtgcagtagt gcgatcgcgg cacactgcag ccttggcttc cctgggctca     3600

agcagtcctc ccacctcagt ctcccaaata gctaggacta caggcgtgcg tgaccaagcc     3660

cagctaattt ttgcattttt tgtagagatg gggttttgcc atgttgctca ggctggtctc     3720

aaactcctga gcactagcaa tccacccacc tctgtttcca aaaaaaaaaa aaaaatgaaa     3780

ggtcaacccc tatgcaaatt accacagcaa aggtttcatt caggagattc ttccatctgg     3840

gcaacctggt tttccaaata tcatttgacc taagtgaatg ttgatactag ctaaagattg     3900

ggtaaattgg ttgaattatt gtattgaagc ttgagctgta gctaaaagta atttaggttt     3960

cccctaagat gttattatgt tagggacata acacttttgg gaggttgttg tgggagatgg     4020

ttgatttagg ttttcaaaag ctagaaataa aatttacatg ccttagattt cataaaattc     4080

tgctctaatt gggtggaagg tgctgtatct aacttgtgtt cctcctaagg ttatgtccta     4140

ataactattc ttttaggagt atacttctac tttatagaag gttgcttttc tttttaattt     4200

tttctaacaa agaaaagaat aaagtattta ttaataagaa ccagaaagca cttgaaactg     4260

atgtttttaa tggctcattt agggtagatt tatttatctc attaacttaa aacagctatg     4320

tgtatgaaat aggtcacaac agaacttgaa caccaggttg gtgtctgagc aatccctttc     4380

ttatgggaaa aacaatgttc ttgtttgaac agagggtatc attgcagtca gtattcacgt     4440

gtatattgtt atataagttg tataatatgc ttgtaaaggc tgagggtgag ctgtatctgg     4500

atgccttttt acaatttgat tttaactttt aaaataaatt taaaacataa aaaaaaaaaa     4560

aa                                                                    4562


<210>  2459
<211>  3692
<212>  DNA
<213>  homo sapiens

<400>  2459
ggcccgcgga gactccacgg ggcgccccgg gcgtgaggca cccactctgg gagcacagag       60

agctcaggta gcctgcctag atggcggcgc gcaccctggg ccgcggcgtc gggaggctgc      120

tgggcagcct gcgagggctc tcggggcagc ccgcgcggcc gccgtgcggg gtgagcgcgc      180

cgcgcagggc ggcctcggga ccctcgggca gcgctcccgc agttgcagca gcagcagcac      240

agccaggctc gtatcccgcg ctgagtgcac aggcagcccg ggagccggcc gccttctggg      300

ggcctctggc gcgggacact ctcgtgtggg acacccccta ccacaccgtc tgggactgcg      360

acttcagcac tggcaagatc ggctggttcc tgggaggcca gttaaatgtc tctgtcaact      420

gcttggacca gcatgttcgg aagtcccccg agagcgttgc tttgatctgg gagcgcgatg      480

agcctggaac ggaagtgagg atcacctaca gggaactact ggagaccacg tgccgcctgg      540

ccaacacgct gaagaggcat ggagtccacc gtggggaccg tgttgccatc tacatgcccg      600

tgtccccatt ggctgtggca gcaatgctgg cctgtgccag gatcggagct gtccacacag      660

tcatctttgc tggcttcagt gcagagtcct tggctgggag gatcaatgat gccaagtgca      720

aggtggttat caccttcaac caaggactcc ggggtgggcg cgtggtggag ctgaagaaaa      780

tagtggatga ggctgtgaag cactgcccca ccgtgcagca tgtcctggtg gctcacagga      840

cagacaacaa ggtccacatg ggggatctgg acgtcccgct ggagcaggaa atggccaagg      900

aggaccctgt ttgcgcccca gagagcatgg gcagtgagga catgctcttc atgctgtaca      960

cctcagggag caccggaatg cccaagggca tcgtccatac ccaggcaggc tacctgctct     1020

atgccgccct gactcacaag cttgtgtttg accaccagcc aggtgacatc tttggctgtg     1080

tggccgacat cggttggatt acaggacaca gctacgtggt gtatgggcct ctctgcaatg     1140

gtgccaccag cgtccttttt gagagcaccc cagtttatcc caatgctggt cggtactggg     1200

agacagtaga gaggttgaag atcaatcagt tctatggcgc cccaacggct gtccggctgt     1260

tgctgaaata cggtgatgcc tgggtgaaga agtatgatcg ctcctccctg cggaccctgg     1320

ggtcagtggg agagcccatc aactgtgagg cctgggagtg gcttcacagg gtggtggggg     1380

acagcaggtg cacgctggtg gacacctggt ggcagacaga aacaggtggc atctgcatcg     1440

caccacggcc ctcggaagaa ggggcggaaa tcctccctgc catggcgatg aggcccttct     1500

ttggcatcgt ccccgtcctc atggatgaga agggcagcgt cgtggagggc agcaacgtct     1560

ccggggccct gtgcatctcc caggcctggc cgggcatggc caggaccatc tatggcgacc     1620

accagcgatt tgtggacgcc tacttcaagg cctacccagg ctattacttc actggagacg     1680

gggcttaccg aactgagggc ggctattacc agatcacagg gcggatggat gatgtcatca     1740

acatcagtgg ccaccggctg gggaccgcag agattgagga cgccatcgcc gaccaccctg     1800

cagtaccaga aagtgctgtc attggctacc cccacgacat caaaggagaa gctgcctttg     1860

ccttcattgt ggtgaaagat agtgcgggtg actcagatgt ggtggtgcag gagctcaagt     1920

ccatggtggc caccaagatc gccaaatatg ctgtgcctga tgagatcctg gtggtgaaac     1980

gtcttccaaa aaccaggtct gggaaggtca tgcggcggct cctgaggaag atcatcacta     2040

gtgaggccca ggagctggga gacactacca ccttggagga ccccagcatc atcgcagaga     2100

tcctgagtgt ctaccagaag tgcaaggaca agcaggctgc tgctaagtga gctggcacct     2160

tgtggggctc ttgggatggg cgggcaccca agccctggct tgtccttccc agaaggtacc     2220

cctgaggttg gcgtcttcct acgtcccaga agcagccccc accccacaca tgacccacac     2280

cgccctcacg tgaagctggg ctgagagccc tttctcccat ccattggagg tcccaggagt     2340

gtcacccatg gagaggctat gcgacatggc tagggctggt tctgccatct gagtttggtt     2400

tcctggaatg aaaaggcatt gccatctcca ttcctctgcc ctcttgagcc agcacaggaa     2460

ggtgaggccc tgggatagcg cgcctgctca gataacacag agctagttag ctagtagcaa     2520

ccgtgttttc tccagatctg tctagataca aaggtcagaa atcttatttt tatactttta     2580

tattgtggaa gaacagcatg caacactcac atgtagtgtg tggatttact tgaacatgtt     2640

ctttttaaca tgtagttatg aaaatctcct tttttgcctc tactggtgag gaaacatgag     2700

gatcagaggc cacattttta attattgtta gtgtatttgg aagtctgaat tggagatgtt     2760

tgtacctctg tctaaacagt tcccttgaga acttccaagc ctccggcatc ttttcctggt     2820

gagtgtttct cctgtgcttg gttgtgtata atggagctaa ctcctaagcg gtggggtgaa     2880

tgtggccgcc ttagttctga agctactcca gttatgttct gtttcttcaa gctgtgatcc     2940

agaaagattt ttgtgccccc agatgcctct tgataggaga ggcaacatac tccaaatagt     3000

tgggttcttc agggaagcta ttagaaactc aggtgacttg ttagagcact aacttggtca     3060

gagccaaatc ctggcaaacg ctgcctgacc ttcactctgt ggttggggcg gtgagaacca     3120

ctgaggtcca atgatgagac ttggaggtct ggatccagtc tctctttgtt ttaatgtgac     3180

ttaggtgctg tcaacattag caagataatg gaaatcacga cgccagtggg tgcttacctc     3240

cctgctaggc atgcaggggc tggcggttgg caggggaagg aggcccagtg agccgggtcc     3300

cttaggggag ggagagtttg tcctctttgc cccacagtct acccttcagg gccttgtggc     3360

agtgccagtg ttcggggggt gtctgggcca ctgagtaccc actcggtcgt ggttgtgctg     3420

gcctcttggg tgagtgaacc tgtgaagccc aggaggtggt gttggctgca gggtacacaa     3480

atactgagtg gtggtctttt gttacaggct tagcaacaaa gctgtgccct gggcatgggg     3540

ggctgtagtg tagctacagt tgtgcgtttg tgaaatggct tagctttcca tgttgctgag     3600

aggaacctgg acatggtccc gggcatctga atgatctgta ggggagggag ttcaaataaa     3660

gctttatttt gttcattttc tcaaaaaaaa aa                                   3692


<210>  2460
<211>  1944
<212>  DNA
<213>  homo sapiens

<400>  2460
tttccttccc tctccctggg cttgggtctc ccacttgtcc agacagcggc cgggcttgtc       60

acggggctct gtgcagcctt ttccactctc ccggctgcca gcgtcccgcc ccgtcccctc      120

ccagccccca agggaggagg ggagagctgc agagaggagg aggggtcggg gaggccggct      180

ttataaaggc ggctggaaca accctgcccg ccagaccccg tcgcccggat cccctgagct      240

gcccgccatc ccacgtgacc gcgccgcccc ccagctccac cgctgagccc gctcgccatg      300

gccctcttcg gggccctctt cctagcgctg ctggcaggcg cacatgcaga gttcccaggc      360

tgcaagatcc gcgtcacctc caaggcgctg gagctggtga agcaggaggg gctgcgcttt      420

ctggagcaag agctggagac tatcaccatt ccggacctgc ggggcaaaga aggccacttc      480

tactacaaca tctctgaggt gaaggtcaca gagctgcaac tgacatcttc cgagctcgat      540

ttccagccac agcaggagct gatgcttcaa atcaccaatg cctccttggg gctgcgcttc      600

cggagacagc tgctctactg gttcttgaag gtgtatgatt ttctctccac gttcatcacc      660

tcagggatgc gcttcctcct caaccagcag atctgccctg tcctctacca cgcagggacg      720

gtcctgctca actccctcct ggacaccgtg cctgtgcgca gttctgtgga cgagcttgtt      780

ggcattgact attccctcat gaaggatcct gtggcttcca ccagcaacct ggacatggac      840

ttccgggggg ccttcttccc cctgactgag aggaactgga gcctccccaa ccgggcagtg      900

gagccccagc tgcaggagga agagcggatg gtgtatgtgg ccttctctga gttcttcttc      960

gactctgcca tggagagcta cttccgggcg ggggccctgc agctgttgct ggtgggggac     1020

aaggtgcccc acgacctgga catgctgctg agggccacct actttgggag cattgtcctg     1080

ctgagcccag cagtgattga ctccccattg aagctggagc tgcgggtcct ggccccaccg     1140

cgctgcacca tcaagccctc tggcaccacc atctctgtca ctgctagcgt caccattgcc     1200

ctggtcccac cagaccagcc tgaggtccag ctgtccagca tgactatgga cgcccgtctc     1260

agcgccaaga tggctctccg ggggaaggcc ctgcgcacgc agctggacct gcgcaggttc     1320

cgaatctatt ccaaccattc tgcactggag tcgctggctc tgatcccatt acaggcccct     1380

ctgaagacca tgctgcagat tggggtgatg cccatgctca atgagcggac ctggcgtggg     1440

gtgcagatcc cactacctga gggcatcaac tttgtgcatg aggtggtgac gaaccatgcg     1500

ggattcctca ccatcggggc tgatctccac tttgccaaag ggctgcgaga ggtgattgag     1560

aagaaccggc ctgctgatgt cagggcgtcc actgccccca caccgtccac agcagctgtc     1620

tgagccctca atccccaagc tggcagctgt cattcaggac cccaacccct ctcagcccct     1680

cttttcccac attcatagcc tgtagtgccc cctctaaccc ccagtgccac agagaagacg     1740

ggatttgaag ctgtacccaa tttaattcca taatcaatct atcaattaca gtccgtccac     1800

cacctccctg tgggctgtcc tgagctctgt tgggttcctg ggatggaatc agtgcatcat     1860

aaagggcatt ctttaagcag agaaggggcc aggccacccc attcaggaac tgctgcggga     1920

ataaagtgct aacttgcccc cagg                                            1944


<210>  2461
<211>  3139
<212>  DNA
<213>  homo sapiens

<400>  2461
cccgatgcct cctctccctt caacgcttct gctgctgctc gctgcttgat gatggcggcc       60

agtattttaa aaaatagcaa aattattcat cggcttcttt ccctcccgtg cctctgcgtg      120

tgtgcgagtg tgtgtgcgtg cgtgtgtgcg tgtctgggcg cgcgtgttcc agcgctgtgc      180

gagcgggcgg gcggcgagtg cgtgtgagtg gtgtgtgtgt gtgcgtgtgc aatcgttaca      240

cgctttcgcc tcgctccagc ttttacccca gcagcgcgat tcccccggtt ctcctgctgc      300

cgctgctgcg ccgctgccgc cgtggctcgc gcggctcggg gcgggcacgg gctgcgtagg      360

agccgccgcc ggggccgccg ctggggccgc gctgccgcag ccgctgcgcc gccgcctaga      420

ctactagcct gggctgcttg ttttgtctct gaaattgaca aggacgcagg gaatccgctg      480

ctaaataatg tttctgtacg atgagctgcc ccattacggc gggatggacg gagtaggggt      540

tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg ttcaccacct      600

gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc cgcaccccaa      660

tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg acaaggacgc      720

gatctatggc tctggtcttt gagaagtgcg agctggcgac ctgcactccc cgggaacctg      780

gagtggctgg cggagacgtc tgctcctccg actccttcaa cgaggacatc gcggtcttcg      840

ccaagcaggt tcgcgccgaa aagccacttt tttcctcaaa tccagagctg gacaatttga      900

tgatacaagc aatacaagta ctaaggtttc atcttttgga gttagaaaag gtccacgaac      960

tgtgcgataa cttctgccac cgatacatta gctgtttgaa ggggaaaatg cccatcgacc     1020

tcgtcattga tgaaagagac ggcagctcca agtcagatca tgaagaactt tcaggctcct     1080

ccacaaatct cgctgaccat aacccttctt cttggcgaga ccacgatgat gcaacctcaa     1140

cccactcagc aggcacccca gggccctcca gtgggggcca tgcttcccag agcggagaca     1200

acagcagtga gcaaggggat ggtttagaca acagtgtagc ttcacctggt acaggtgacg     1260

atgatgatcc ggataaggac aaaaaacgcc agaagaaaag aggcattttc cccaaagtag     1320

caacaaatat catgagagca tggctcttcc agcatctcac acatccgtac ccttccgaag     1380

agcagaagaa acagttagcg caagacacag gacttacaat tctccaagta aacaactggt     1440

ttattaatgc cagaagaaga atagtacagc ccatgattga ccagtcaaat cgagcagtga     1500

gccaaggagc agcatatagt ccagagggtc agcccatggg gagctttgtg ttggatggtc     1560

agcaacacat ggggatccgg cctgcaggac ctatgagtgg aatgggcatg aatatgggca     1620

tggatgggca atggcactac atgtaacctt catcatgtaa agcaatcgca aagcaagggg     1680

gaagtttgca gagcatgcca ggggactacg tttctcaggg tggtcctatg ggaatgagta     1740

tggcacagcc aagttacact cctccccaga tgaccccaca ccctactcaa ttaagacatg     1800

gacccccaat gcattcatat ttgccaagcc atccccacca cccagccatg atgatgcacg     1860

gaggaccccc tacccaccct ggaatgacta tgtcagcaca gagccccaca atgttaaatt     1920

ctgtagatcc caatgttggc ggacaggtta tggacattca tgcccaatag tataagggaa     1980

ctcaagggaa aaggaaacac acgcaaaaac tattttaaga ctttctgaac tttgaccaga     2040

tgttgacact taatatgaaa ttccagacag ctgtgattat tttttacttt tgtcattttt     2100

catcaagcaa cagaggacca atgcaacaag aacacaaatg tgaaatcatg ggctgactga     2160

gacaattctg tccatgtaaa gatcctctgg aaaaagactc cgagagttat aactactgta     2220

gtataaatat aggaactaag ttaaacttgt acatttctgt tgatcacgcc gttatgttgc     2280

ctcaaatagt tttagaagag aaaaaaaaat atatccttgt tttccacact atgtgtgttg     2340

ttcccaaaag aatgactgtt ttggttcatc agtgaattca ccatccagga gagactgtgg     2400

tatatatttt aaacctgttg ggccaatgag aaaagaacca cactggagat catgatgaac     2460

ttttggctga acctcatcac tcgaactcca gcttcaagaa tgtgttttca tgcccggcct     2520

ttgttcctcc ataaatgtgt cctttagttt caaacagatc tttatagttc gtgcttcata     2580

agccaattct tattattatt tttgggggac tcttcttcaa agagcttgcc aatgaagatt     2640

taaagacaga gcaggagctt cttccaggag ttctgagcct tggttgtgga caaaacaatc     2700

ttaagttggg cagctttcct caacacaaaa aaaagttatt aatggtcatt gaaccataac     2760

taggacttta tcagaaactc aaagcttggg ggataaaaag gagcaagaga atactgtaac     2820

aaacttcgta cagagttcgg tctattaatt gtttcatgtt agatattcta tgtgtttacc     2880

tcaattgaaa aaaaaaagaa tgtttttgct agtatcagat ctgctgtgga attggtattg     2940

tatgtccatg aattcttctt ttctcagcac gtgttcctca ctagaagaaa atgctgttac     3000

ctttaagctt tgtcaaattt acattaaaat acttgtatga ggactgtgac gttatgttaa     3060

aaaaaaaaag gtgttaagtc acaaaaagcg gtaataaata tttcattttt gattttttgt     3120

taaaaaaaaa aaaaaaaaa                                                  3139


<210>  2462
<211>  3373
<212>  DNA
<213>  homo sapiens

<400>  2462
tttaaagaga gaggatcgta ttatagatac cgcgggggca aagctaaaaa aggggggagg       60

ggggaggaaa aaattcaaga agcagaaacc cctcgcggag ttttactgga agaaaaaaac      120

gggtctgaaa gattcctcct cttcatcatc atcaaccatc attcattcac taccttgaca      180

ttccgggctt tgattgacag ctggagtggc aaaaagccat gaaacacgac agttcggtta      240

catgtgggct gctgacgggc cgctcgtaac cttcagttcg ggggcttgac aatttttttc      300

ttctttttct tctttttctt ttctttcttt ttttttccaa ctgaggggaa gagaagagaa      360

agagggggaa aggaggaccg aagaggagga ggaggggagg ggggaggagg aggaggtgga      420

ggaggaggag gaagatcagg aggaggagga agaagaggaa aaaagagaaa aagaagaaat      480

atcacagaaa aaaaaattct tcgttgtcta gactgggctt tttttccccc ctaaaaaata      540

gcatattgga gaattgggag aagtctcttt ggtttggaaa aaaaaaaaag gaatcttcag      600

cctagatcac tttcttatcc ggactgggat attaaatata cgacacatcc aggagtttat      660

tggagcgcag actgatggcg caaaggtacg atgagctgcc ccattacggc gggatggacg      720

gagtaggggt tcccgcttcc atgtacggag accctcacgc gccgcggccg atccccccgg      780

ttcaccacct gaaccacggg ccgccgctcc acgccacaca gcactacggc gcgcacgccc      840

cgcaccccaa tgtcatgccg gccagtatgg gatccgctgt caacgacgcc ttgaagcggg      900

acaaggacgc gatctatggg cacccgttgt ttcctctgtt agctctggtc tttgagaagt      960

gcgagctggc gacctgcact ccccgggaac ctggagtggc tggcggagac gtctgctcct     1020

ccgactcctt caacgaggac atcgcggtct tcgccaagca ggttcgcgcc gaaaagccac     1080

ttttttcctc aaatccagag ctggacaatt tgatgataca agcaatacaa gtactaaggt     1140

ttcatctttt ggagttagaa aaggtccacg aactgtgcga taacttctgc caccgataca     1200

ttagctgttt gaaggggaaa atgcccatcg acctcgtcat tgatgaaaga gacggcagct     1260

ccaagtcaga tcatgaagaa ctttcaggct cctccacaaa tctcgctgac cataaccctt     1320

cttcttggcg agaccacgat gatgcaacct caacccactc agcaggcacc ccagggccct     1380

ccagtggggg ccatgcttcc cagagcggag acaacagcag tgagcaaggg gatggtttag     1440

acaacagtgt agcttcacct ggtacaggtg acgatgatga tccggataag gacaaaaaac     1500

gccagaagaa aagaggcatt ttccccaaag tagcaacaaa tatcatgaga gcatggctct     1560

tccagcatct cacacatccg tacccttccg aagagcagaa gaaacagtta gcgcaagaca     1620

caggacttac aattctccaa gtaaacaact ggtttattaa tgccagaaga agaatagtac     1680

agcccatgat tgaccagtca aatcgagcag gttttcttct tgatccttca gtgagccaag     1740

gagcagcata tagtccagag ggtcagccca tggggagctt tgtgttggat ggtcagcaac     1800

acatggggat ccggcctgca ggacctatga gtggaatggg catgaatatg ggcatggatg     1860

ggcaatggca ctacatgtaa ccttcatcat gtaaagcaat cgcaaagcaa gggggaagtt     1920

tgcagagcat gccaggggac tacgtttctc agggtggtcc tatgggaatg agtatggcac     1980

agccaagtta cactcctccc cagatgaccc cacaccctac tcaattaaga catggacccc     2040

caatgcattc atatttgcca agccatcccc accacccagc catgatgatg cacggaggac     2100

cccctaccca ccctggaatg actatgtcag cacagagccc cacaatgtta aattctgtag     2160

atcccaatgt tggcggacag gttatggaca ttcatgccca atagtataag ggaactcaag     2220

ggaaaaggaa acacacgcaa aaactatttt aagactttct gaactttgac cagatgttga     2280

cacttaatat gaaattccag acagctgtga ttatttttta cttttgtcat ttttcatcaa     2340

gcaacagagg accaatgcaa caagaacaca aatgtgaaat catgggctga ctgagacaat     2400

tctgtccatg taaagatcct ctggaaaaag actccgagag ttataactac tgtagtataa     2460

atataggaac taagttaaac ttgtacattt ctgttgatca cgccgttatg ttgcctcaaa     2520

tagttttaga agagaaaaaa aaatatatcc ttgttttcca cactatgtgt gttgttccca     2580

aaagaatgac tgttttggtt catcagtgaa ttcaccatcc aggagagact gtggtatata     2640

ttttaaacct gttgggccaa tgagaaaaga accacactgg agatcatgat gaacttttgg     2700

ctgaacctca tcactcgaac tccagcttca agaatgtgtt ttcatgcccg gcctttgttc     2760

ctccataaat gtgtccttta gtttcaaaca gatctttata gttcgtgctt cataagccaa     2820

ttcttattat tatttttggg ggactcttct tcaaagagct tgccaatgaa gatttaaaga     2880

cagagcagga gcttcttcca ggagttctga gccttggttg tggacaaaac aatcttaagt     2940

tgggcagctt tcctcaacac aaaaaaaagt tattaatggt cattgaacca taactaggac     3000

tttatcagaa actcaaagct tgggggataa aaaggagcaa gagaatactg taacaaactt     3060

cgtacagagt tcggtctatt aattgtttca tgttagatat tctatgtgtt tacctcaatt     3120

gaaaaaaaaa agaatgtttt tgctagtatc agatctgctg tggaattggt attgtatgtc     3180

catgaattct tcttttctca gcacgtgttc ctcactagaa gaaaatgctg ttacctttaa     3240

gctttgtcaa atttacatta aaatacttgt atgaggactg tgacgttatg ttaaaaaaaa     3300

aaaggtgtta agtcacaaaa agcggtaata aatatttcat ttttgatttt ttgttaaaaa     3360

aaaaaaaaaa aaa                                                        3373


<210>  2463
<211>  1211
<212>  DNA
<213>  homo sapiens

<400>  2463
ctggactctg agtgtggagc caggggcagc agggctgtct ctgaactccc aggcttgtgt       60

ttgagcaaag gaattctctc cccctccctc tcccctcggg gcgggcccga gcctccagct      120

ataaactccc cggagcttca gtgccctcag caaggctcag cctcaagatt cacagcatct      180

cagacacagc ctaggccgca ccaggatgtc ggacaccgag gagcaggaat atgaggagga      240

gcagccggaa gaggaggctg cggaggagga ggaggaagcc cccgaagagc cggagccggt      300

ggcagagcca gaagaggaac gccccaaacc aagccgcccc gtggtgcctc ctttgatccc      360

gccaaagatc ccagaagggg agcgcgttga cttcgatgac atccaccgca agcgcatgga      420

gaaagacctg ctggagctgc agacactcat cgatgtacat ttcgagcagc ggaagaagga      480

ggaagaggag ctggttgcct tgaaggagcg cattgagcgg cgccggtcag agagagccga      540

gcaacagcgc ttcagaactg agaaggaacg cgaacgtcag gctaagctgg cggaggagaa      600

gatgaggaag gaagaggaag aggccaagaa gcgggcagag gatgatgcca agaaaaagaa      660

ggtgctgtcc aacatggggg cccattttgg cggctacctg gtcaaggcag aacagaagcg      720

tggtaagcgg cagacggggc gggagatgaa ggtgcgcatc ctctccgagc gtaagaagcc      780

tctggacatt gactacatgg gggaggaaca gctccgggag aaagcccagg agctgtcgga      840

ctggatccac cagctggagt ctgagaagtt cgacctgatg gcgaagctga aacagcagaa      900

atatgagatc aacgtgctgt acaaccgcat cagccacgcc cagaagttcc ggaagggggc      960

agggaagggc cgcgttggag gccgctggaa gtgaggatgc cgccccggac agtggcacct     1020

gggaagcctg ggagtgtttg tcccatcggt agcttgaaat aaacgctccc ctcagacacc     1080

cgctgggttc tctgatgtta ttatggttga gatgcagctg gtctctcctg gttaattgac     1140

ttcttattac caacaagtta cttgaaagag tgtcaccaat aatcattaaa gtacggcagg     1200

ctgaaccttc a                                                          1211


<210>  2464
<211>  1178
<212>  DNA
<213>  homo sapiens

<400>  2464
ctggactctg agtgtggagc caggggcagc agggctgtct ctgaactccc aggcttgtgt       60

ttgagcaaag gaattctctc cccctccctc tcccctcggg gcgggcccga gcctccagct      120

ataaactccc cggagcttca gtgccctcag caaggctcag cctcaagatt cacagcatct      180

cagacacagc ctaggccgca ccaggatgtc ggacaccgag gagcaggaat atgaggagga      240

gcagccggaa gaggaggctg cggaggagga ggaggaagaa gaggaacgcc ccaaaccaag      300

ccgccccgtg gtgcctcctt tgatcccgcc aaagatccca gaaggggagc gcgttgactt      360

cgatgacatc caccgcaagc gcatggagaa agacctgctg gagctgcaga cactcatcga      420

tgtacatttc gagcagcgga agaaggagga agaggagctg gttgccttga aggagcgcat      480

tgagcggcgc cggtcagaga gagccgagca acagcgcttc agaactgaga aggaacgcga      540

acgtcaggct aagctggcgg aggagaagat gaggaaggaa gaggaagagg ccaagaagcg      600

ggcagaggat gatgccaaga aaaagaaggt gctgtccaac atgggggccc attttggcgg      660

ctacctggtc aaggcagaac agaagcgtgg taagcggcag acggggcggg agatgaaggt      720

gcgcatcctc tccgagcgta agaagcctct ggacattgac tacatggggg aggaacagct      780

ccgggagaaa gcccaggagc tgtcggactg gatccaccag ctggagtctg agaagttcga      840

cctgatggcg aagctgaaac agcagaaata tgagatcaac gtgctgtaca accgcatcag      900

ccacgcccag aagttccgga agggggcagg gaagggccgc gttggaggcc gctggaagtg      960

aggatgccgc cccggacagt ggcacctggg aagcctggga gtgtttgtcc catcggtagc     1020

ttgaaataaa cgctcccctc agacacccgc tgggttctct gatgttatta tggttgagat     1080

gcagctggtc tctcctggtt aattgacttc ttattaccaa caagttactt gaaagagtgt     1140

caccaataat cattaaagta cggcaggctg aaccttca                             1178


<210>  2465
<211>  3985
<212>  DNA
<213>  homo sapiens

<400>  2465
tttttttccc cgcctcccaa ccgtgaggtg ttgggtttgg gggacgctgg cagctgggtt       60

ctcccggttc ccttgggcag gtgcagggtc gggttcaaag cctccggaac gcgttttggc      120

ctgatttgag gaggggggcg gggagggacc tgcggcttgc ggccccgccc ccttctccgg      180

ctcgcagccg accggtaagc ccgcctcctc cctcggccgg ccctggggcc gtgtccgccg      240

ggcaactcca gccgaggcct gggcttctgc ctgcaggtgt ctgcggcgag gcccctaggg      300

tacagcccga tttggcccca tggtgggttt cggggccaac cggcgggctg gccgcctgcc      360

ctctctcgtg ctggtggtgc tgctggtggt gatcgtcgtc ctcgccttca actactggag      420

catctcctcc cgccacgtcc tgcttcagga ggaggtggcc gagctgcagg gccaggtcca      480

gcgcaccgaa gtggcccgcg ggcggctgga aaagcgcaat tcggacctct tgctgttggt      540

ggacacgcac aagaaacaga tcgaccagaa ggaggccgac tacggccgcc tcagcagccg      600

gctgcaggcc agagagggcc tcgggaagag atgcgaggat gacaaggtta aactacagaa      660

caacatatcg tatcagatgg cagacataca tcatttaaag gagcaacttg ctgagcttcg      720

tcaggaattt cttcgacaag aagaccagct tcaggactat aggaagaaca atacttacct      780

tgtgaagagg ttagaatatg aaagttttca gtgtggacag cagatgaagg aattgagagc      840

acagcatgaa gaaaatatta aaaagttagc agaccagttt ttagaggaac aaaagcaaga      900

gacccaaaag attcaatcaa atgatggaaa ggaattggat ataaacaatc aagtagtacc      960

taaaaatatt ccaaaagtag ctgagaatgt tgcagataag aatgaagaac cctcaagcaa     1020

tcatattcca catgggaaag aacaaatcaa aagaggtggt gatgcaggga tgcctggaat     1080

agaagagaat gacctagcaa aagttgatga tcttccccct gctttaagga agcctcctat     1140

ttcagtttct caacatgaaa gtcatcaagc aatctcccat cttccaactg gacaacctct     1200

ctccccaaat atgcctccag attcacacat aaaccacaat ggaaaccccg gtacttcaaa     1260

acagaatcct tccagtcctc ttcagcgttt aattccaggc tcaaacttgg acagtgaacc     1320

cagaattcaa acagatatac taaagcaggc taccaaggac agagtcagtg atttccataa     1380

attgaagcaa agccgattct ttgatgaaaa tgaatcccct gttgatccgc agcatggctc     1440

taaactggcg gattataatg gggatgatgg taacgtaggt gagtatgagg cagacaagca     1500

ggctgagctg gcttacaatg aggaagaaga tggtgatggt ggagaggaag acgtccaaga     1560

tgatgaagaa cgagagcttc aaatggatcc tgcagactat ggaaagcaac atttcaatga     1620

tgtcctttaa gtcctaaagg aatgcttcag aaaacctaaa gtgctgtaaa atgaaatcat     1680

tctactttgt cctttctgac ttttgttgta aagacgaatt gtatcagttg taaagataca     1740

ttgagataga attaaggaaa aactttaatg aaggaatgta cccatgtaca tatgtgaact     1800

ttttcatatt gtattatcaa ggtatagact tttttggtta tgatacagtt aagccaaaaa     1860

cagctaatct ttgcatctaa agcaaactaa tgtatatttc acattttatt gagccgactt     1920

atttccacaa atagataaac aggacaaaat agttgtacag gttatatgtg gcatagcata     1980

accacagtaa gaacagaaca gatattcagc agaaaacttt ttatactcta attctttttt     2040

tttttttttt tgagacagag ttttagtctt gtttcccagg ctggagtgca atggcacaat     2100

cttggctcac tgcaacctcc gcctcctggg ttcaggcaat tttcctgcct cagcctccca     2160

agtagctggg attacaggca cccaccacca tgcccagcta atttttgtat ttttaataga     2220

gagctaataa ttgtatattt aataaagacg ggtttcacca tgttggccag gctggtcttg     2280

aactcctgac ctcaggtgat cctcctgcat tggcctccca aagtgctgga attccaggca     2340

tgagccactg cgcccagtct acacactaat tcttgttagc ccaacagctg ttctgttcta     2400

tctacccctc atttcacgct caaggagtca tacctagaat agttacacac aagagggaaa     2460

ctggaagcca aacactgtac agtattgtgt agaaagtcac ctccctactc cttttatttt     2520

acatgagtgc tgatgtgttt tggcagatga gctttcagct gaggcctgat ggaaattgag     2580

ataacctgca aagacataac agtatttatg agttatatct tagttcttga aattgtggaa     2640

tgcatgattg acaatatatt tttaattttt attttttcaa gtaataccag tactgtttaa     2700

ctatagccag aactggctaa aatttttata ttttcagagt tgaagttggt gaagacattc     2760

atgatttaaa caccagatcc tgaaaggggt taaatctact ttgaaatgaa tctgcaatca     2820

gtatttcaaa gcttttctgg taattttagt gatcttattt gattagactt tttcagaagt     2880

actaaataag gaattttaac aggtttttat taatgcacag ataaatagaa gtacagtgag     2940

gtctatagcc attttattaa aatagcttaa aagtttgtaa aaaaatgaat ctttgtaatt     3000

acttaatatg ttagttaaga acccgtcaag cttatatttg ctagacttac aaattatttt     3060

aaatgcattt atcttttttg acactattca gtggaatgtg taagctagct aattcttgtt     3120

ttctgattta aagcactttt aaatcttatc ctgcccccta aaaacaaaag gttttgatca     3180

caaggggaaa tttaagattg ttaaccctgt ttttcagaag ggctactgtt aattgcacat     3240

aaacatgaaa tgtgttttcc cctgtgtact aacacattct aggcaaaatt caaacttata     3300

gtggtaaaga aacaggttgt tcacttgctg aggtgcaaaa attcttaaga cttctgtttg     3360

aaattgctca atgactagga aaagatgtag tagtttacta aaattgtttt tctaccatat     3420

caaattaaac aattcatgcc tttatagggt caggcctaca atgaataggt atggtggttt     3480

cacagaattt taaaatagag ttaaagggaa gtgatgtaca tttcgggggc attagggtag     3540

ggagatgaat caaaaaatac ccctagtaat gctttatatt ttaatactgc aaaagcttta     3600

caaatggaaa ccatgcaatt acctgcctta gttcttttgt cataaaaaca atcacttggt     3660

tggttgtatt gtagctatta cttatacagc aacatttctt caattagcag tctagacatt     3720

ttataaacag aaatcttgga ccaattgata atatttctga ctgtattaat attttagtgc     3780

tataaaatac tatgtgaatc tcttaaaaat ctgacatttt acagtctgta ttagacatac     3840

tgtttttata atgttttact tctgccttaa gatttaggtt ttttaaatgt atttttgccc     3900

tgaattaagt gttaatttga tggaaactct gcttttaaaa tcatcattta ctgggttcta     3960

ataaattaaa aattaaactt gtttc                                           3985


<210>  2466
<211>  3197
<212>  DNA
<213>  homo sapiens

<400>  2466
aatagactaa acccagagcc tcaaagcagt gcactccgtg aaggcaaaga gaacacgctg       60

caaaaggctt tccaagaatc ctcgacatgg caaggaggag ctcgttccag tcgtgtcaga      120

taatatccct gttcactttt gccgttggag tcaatatctg cttaggattc actgcacatc      180

gaattaagag agcagaagga tgggaggaag gtcctcctac agtgctatca gactccccct      240

ggaccaacat ctccggatct tgcaagggca ggtgctttga acttcaagag gctggacctc      300

ctgattgtcg ctgtgacaac ttgtgtaaga gctataccag ttgctgccat gactttgatg      360

agctgtgttt gaagacagcc cgtggctggg agtgtactaa ggacagatgt ggagaagtca      420

gaaatgaaga aaatgcctgt cactgctcag aggactgctt ggccagggga gactgctgta      480

ccaattacca agtggtttgc aaaggagagt cgcattgggt tgatgatgac tgtgaggaaa      540

taaaggccgc agaatgccct gcagggtttg ttcgccctcc attaatcatc ttctccgtgg      600

atggcttccg tgcatcatac atgaagaaag gcagcaaagt catgcctaat attgaaaaac      660

taaggtcttg tggcacacac tctccctaca tgaggccggt gtacccaact aaaacctttc      720

ctaacttata cactttggcc actgggctat atccagaatc acatggaatt gttggcaatt      780

caatgtatga tcctgtattt gatgccactt ttcatctgcg agggcgagag aaatttaatc      840

atagatggtg gggaggtcaa ccgctatgga ttacagccac caagcaaggg gtgaaagctg      900

gaacattctt ttggtctgtt gtcatccctc acgagcggag aatattaacc atattgcagt      960

ggctcaccct gccagatcat gagaggcctt cggtctatgc cttctattct gagcaacctg     1020

atttctctgg acacaaatat ggccctttcg gccctgagat gacaaatcct ctgagggaaa     1080

tcgacaaaat tgtggggcaa ttaatggatg gactgaaaca actaaaactg catcggtgtg     1140

tcaacgtcat ctttgtcgga gaccatggaa tggaagatgt cacatgtgat agaactgagt     1200

tcttgagtaa ttacctaact aatgtggatg atattacttt agtgcctgga actctaggaa     1260

gaattcgatc caaatttagc aacaatgcta aatatgaccc caaagccatt attgccaatc     1320

tcacgtgtaa aaaaccagat cagcacttta agccttactt gaaacagcac cttcccaaac     1380

gtttgcacta tgccaacaac agaagaattg aggatatcca tttattggtg gaacgcagat     1440

ggcatgttgc aaggaaacct ttggatgttt ataagaaacc atcaggaaaa tgctttttcc     1500

agggagacca cggatttgat aacaaggtca acagcatgca gactgttttt gtaggttatg     1560

gctcaacatt taagtacaag actaaagtgc ctccatttga aaacattgaa ctttacaatg     1620

ttatgtgtga tctcctggga ttgaagccag ctcctaataa tgggacccat ggaagtttga     1680

atcatctcct gcgcactaat accttcaggc caaccatgcc agaggaagtt accagaccca     1740

attatccagg gattatgtac cttcagtctg attttgacct gggctgcact tgtgatgata     1800

aggtagagcc aaagaacaag ttggatgaac tcaacaaacg gcttcataca aaagggtcta     1860

cagaagctga aaccaggaaa ttcagaggca gcagaaatga aaacaaggaa aacattaatg     1920

gaaattttga acctagaaaa gagagacacc tcctctatgg gcgacctgca gtgctttatc     1980

ggactagata tgatatctta tatcacactg actttgaaag tggttatagt gaaatattcc     2040

taatgccact ctggacatca tatactgttt ccaaacaggc tgaggtttcc agcgttcctg     2100

accatctgac cagttgcgtc cggcctgatg tccgtgtttc tccgagtttc agtcagaact     2160

gtttggccta caaaaatgat aagcagatgt cctacggatt cctctttcct ccttatctga     2220

gctcttcacc agaggctaaa tatgatgcat tccttgtaac caatatggtt ccaatgtatc     2280

ctgctttcaa acgggtctgg aattatttcc aaagggtatt ggtgaagaaa tatgcttcgg     2340

aaagaaatgg agttaacgtg ataagtggac caatcttcga ctatgactat gatggcttac     2400

atgacacaga agacaaaata aaacagtacg tggaaggcag ttccattcct gttccaactc     2460

actactacag catcatcacc agctgtctgg atttcactca gcctgccgac aagtgtgacg     2520

gccctctctc tgtgtcctcc ttcatcctgc ctcaccggcc tgacaacgag gagagctgca     2580

atagctcaga ggacgaatca aaatgggtag aagaactcat gaagatgcac acagctaggg     2640

tgcgtgacat tgaacatctc accagcctgg acttcttccg aaagaccagc cgcagctacc     2700

cagaaatcct gacactcaag acatacctgc atacatatga gagcgagatt taactttctg     2760

agcatctgca gtacagtctt atcaactggt tgtatatttt tatattgttt ttgtatttat     2820

taatttgaaa ccaggacatt aaaaatgtta gtattttaat cctgtaccaa atctgacata     2880

ttatgcctga atgactccac tgtttttctc taatgcttga tttaggtagc cttgtgttct     2940

gagtagagct tgtaataaat actgcagctt gagtttttag tggaagcttc taaatggtgc     3000

tgcagatttg atatttgcat tgaggaaata ttaattttcc aatgcacagt tgccacattt     3060

agtcctgtac tgtatggaaa cactgatttt gtaaagttgc ctttatttgc tgttaactgt     3120

taactatgac agatatattt aagccttata aaccaatctt aaacataata aatcacacat     3180

tcagtttttt ctggttt                                                    3197


<210>  2467
<211>  3278
<212>  DNA
<213>  homo sapiens

<400>  2467
aatagactaa acccagagcc tcaaagcagt gcactccgtg aaggcaaaga gaacacgctg       60

caaaaggctt tccaagaatc ctcgacatgg caaggaggag ctcgttccag tcgtgtcaga      120

taatatccct gttcactttt gccgttggag tcaatatctg cttaggattc actgcacatc      180

gaattaagag agcagaagga tgggaggaag gtcctcctac agtgctatca gactccccct      240

ggaccaacat ctccggatct tgcaagggca ggtgctttga acttcaagag gctggacctc      300

ctgattgtcg ctgtgacaac ttgtgtaaga gctataccag ttgctgccat gactttgatg      360

agctgtgttt gaagacagcc cgtggctggg agtgtactaa ggacagatgt ggagaagtca      420

gaaatgaaga aaatgcctgt cactgctcag aggactgctt ggccagggga gactgctgta      480

ccaattacca agtggtttgc aaaggagagt cgcattgggt tgatgatgac tgtgaggaaa      540

taaaggccgc agaatgccct gcagggtttg ttcgccctcc attaatcatc ttctccgtgg      600

atggcttccg tgcatcatac atgaagaaag gcagcaaagt catgcctaat attgaaaaac      660

taaggtcttg tggcacacac tctccctaca tgaggccggt gtacccaact aaaacctttc      720

ctaacttata cactttggcc actgggctat atccagaatc acatggaatt gttggcaatt      780

caatgtatga tcctgtattt gatgccactt ttcatctgcg agggcgagag aaatttaatc      840

atagatggtg gggaggtcaa ccgctatgga ttacagccac caagcaaggg gtgaaagctg      900

gaacattctt ttggtctgtt gtcatccctc acgagcggag aatattaacc atattgcagt      960

ggctcaccct gccagatcat gagaggcctt cggtctatgc cttctattct gagcaacctg     1020

atttctctgg acacaaatat ggccctttcg gccctgagga gagtagttat ggctcacctt     1080

ttactccggc taagagacct aagaggaaag ttgcccctaa gaggagacag gaaagaccag     1140

ttgctcctcc aaagaaaaga agaagaaaaa tacataggat ggatcattat gctgcggaaa     1200

ctcgtcagga caaaatgaca aatcctctga gggaaatcga caaaattgtg gggcaattaa     1260

tggatggact gaaacaacta aaactgcatc ggtgtgtcaa cgtcatcttt gtcggagacc     1320

atggaatgga agatgtcaca tgtgatagaa ctgagttctt gagtaattac ctaactaatg     1380

tggatgatat tactttagtg cctggaactc taggaagaat tcgatccaaa tttagcaaca     1440

atgctaaata tgaccccaaa gccattattg ccaatctcac gtgtaaaaaa ccagatcagc     1500

actttaagcc ttacttgaaa cagcaccttc ccaaacgttt gcactatgcc aacaacagaa     1560

gaattgagga tatccattta ttggtggaac gcagatggca tgttgcaagg aaacctttgg     1620

atgtttataa gaaaccatca ggaaaatgct ttttccaggg agaccacgga tttgataaca     1680

aggtcaacag catgcagact gtttttgtag gttatggctc aacatttaag tacaagacta     1740

aagtgcctcc atttgaaaac attgaacttt acaatgttat gtgtgatctc ctgggattga     1800

agccagctcc taataatggg acccatggaa gtttgaatca tctcctgcgc actaatacct     1860

tcaggccaac catgccagag gaagttacca gacccaatta tccagggatt atgtaccttc     1920

agtctgattt tgacctgggc tgcacttgtg atgataaggt agagccaaag aacaagttgg     1980

atgaactcaa caaacggctt catacaaaag ggtctacaga agagagacac ctcctctatg     2040

ggcgacctgc agtgctttat cggactagat atgatatctt atatcacact gactttgaaa     2100

gtggttatag tgaaatattc ctaatgccac tctggacatc atatactgtt tccaaacagg     2160

ctgaggtttc cagcgttcct gaccatctga ccagttgcgt ccggcctgat gtccgtgttt     2220

ctccgagttt cagtcagaac tgtttggcct acaaaaatga taagcagatg tcctacggat     2280

tcctctttcc tccttatctg agctcttcac cagaggctaa atatgatgca ttccttgtaa     2340

ccaatatggt tccaatgtat cctgctttca aacgggtctg gaattatttc caaagggtat     2400

tggtgaagaa atatgcttcg gaaagaaatg gagttaacgt gataagtgga ccaatcttcg     2460

actatgacta tgatggctta catgacacag aagacaaaat aaaacagtac gtggaaggca     2520

gttccattcc tgttccaact cactactaca gcatcatcac cagctgtctg gatttcactc     2580

agcctgccga caagtgtgac ggccctctct ctgtgtcctc cttcatcctg cctcaccggc     2640

ctgacaacga ggagagctgc aatagctcag aggacgaatc aaaatgggta gaagaactca     2700

tgaagatgca cacagctagg gtgcgtgaca ttgaacatct caccagcctg gacttcttcc     2760

gaaagaccag ccgcagctac ccagaaatcc tgacactcaa gacatacctg catacatatg     2820

agagcgagat ttaactttct gagcatctgc agtacagtct tatcaactgg ttgtatattt     2880

ttatattgtt tttgtattta ttaatttgaa accaggacat taaaaatgtt agtattttaa     2940

tcctgtacca aatctgacat attatgcctg aatgactcca ctgtttttct ctaatgcttg     3000

atttaggtag ccttgtgttc tgagtagagc ttgtaataaa tactgcagct tgagttttta     3060

gtggaagctt ctaaatggtg ctgcagattt gatatttgca ttgaggaaat attaattttc     3120

caatgcacag ttgccacatt tagtcctgta ctgtatggaa acactgattt tgtaaagttg     3180

cctttatttg ctgttaactg ttaactatga cagatatatt taagccttat aaaccaatct     3240

taaacataat aaatcacaca ttcagttttt tctggttt                             3278


<210>  2468
<211>  3938
<212>  DNA
<213>  homo sapiens

<400>  2468
cgtttaaaag ccatcagatt tgagagcaat aagtcttcaa aaccgggaat ttacattgtt       60

tttcagctga ccgacttcca ggaaaaggac tcaaccgcat ctacccaaat accgtggcac      120

tgcttgcgct ctttgccacc ggatcctccc cttccaatga gactttctga ttgtgtctac      180

caactctcct attaggaaac ccgtgggttg catgcagcta ttctgttgta ttctcattct      240

cactctccct cccttctctc actctcactc ttgctggagg cgagccacta ccattctgct      300

gagaaggaaa agcccgcaac tactttaaga gattaagaca atatgcgcaa tcctcgcctt      360

tcctagcaat cactatttaa atctggcaag aactgacaac agtctttgca agaatggaat      420

ccgtaaaaca aaggattttg gccccaggaa aagaggggct aaagaatttt gctggaaaat      480

cactcggcca gatctacagg gtgctggaga agaagcaaga caccggggag acaatcgagc      540

tgacggagga tgggaagccc ctagaggtgc ccgagaggaa ggcgccgctg tgcgactgca      600

cgtgcttcgg cctgccccgc cgctacatta tcgccatcat gagcggcctg ggcttctgca      660

tctccttcgg tatccgctgc aacctgggcg tggccattgt ggacatggtc aacaacagca      720

ccatccaccg cgggggcaag gtcatcaagg agaaagccaa attcaactgg gacccggaaa      780

ccgtggggat gatccacggt tccttctttt ggggctacat catcactcag attccgggag      840

gctacatcgc gtctcggctg gcagccaaca gggttttcgg agctgccata cttcttacct      900

ctaccctaaa tatgctaatt ccatcagcag ccagagtgca ttatggatgt gtcatctttg      960

tcagaatact gcagggactt gttgagggtg tgacctaccc agcatgtcat gggatatgga     1020

gcaaatgggc cccacctcta gagaggagta gactggcaac cacctccttt tgtggttcct     1080

atgccggagc tgtgattgca atgcctttag ctggcattct tgtgcagtac actggctggt     1140

cttcagtgtt ttatgtctac ggaagctttg gaatggtctg gtacatgttt tggcttttgg     1200

tgtcttatga aagtcctgca aagcatccta ctattacaga tgaagaacgt aggtacatag     1260

aagaaagcat tggagagagt gcaaatcttt taggtgcaat ggaaaaattc aagactccat     1320

ggaggaagtt ttttacatcc atgccagtct atgcaataat tgttgcaaac ttctgcagaa     1380

gctggacttt ttatttattg cttattagtc agccagcata ttttgaggaa gtctttggat     1440

ttgaaattag caaggttggt atgctatctg ctgtgccaca cttagtaatg acaattattg     1500

tgcctattgg gggacaaatt gcagattttc taagaagcaa gcagattctt tcaactacga     1560

cagtgagaaa gatcatgaat tgtggtggtt ttggcatgga agccacactg ctcctggtcg     1620

ttggctattc tcatactaga ggggtagcaa tctcattctt ggtacttgca gtgggattca     1680

gtggatttgc tatatctggt ttcaatgtta accacttgga tatcgctcca agatatgcca     1740

gtatcttaat gggcatttcg aatggtgttg gcacattgtc aggaatggtt tgtcctatca     1800

ttgttggtgc aatgacaaag aataagtcac gtgaagagtg gcagtatgtc ttcctgatcg     1860

ctgccctagt ccactatggt ggagttatat tttatgcaat atttgcctca ggagagaaac     1920

aaccctgggc agacccggag gaaacaagtg aagaaaaatg tggatttatt catgaagatg     1980

aactcgatga agaaacaggg gacattactc aaaattatat aaattatggt accaccaagt     2040

cttatggtgc cacaacacag gccaatggag gttggcctag tggttgggaa aagaaagagg     2100

aatttgtaca aggagaagta caagactcac atagctataa ggaccgagtt gattattcat     2160

aacaaaacta attactggat ttatttttag tgtttgtgat taaattcatt gtgattgcac     2220

aaaaatttta aaaacacgtg atgtaaactt gcaagcatat caaccaggca agtcttgctg     2280

taaaaatgaa aacaaaacaa acccatgagg ttaccatcaa gtgcaatctg taaaattgtg     2340

aagttccatc atttccattc aagtcatcca ttcttgcatt tgtgacttaa aggttgactg     2400

gtcaaaattg tagaaacaag tagttaccca ttggattcat atgagctaaa actcatcact     2460

atttactaaa gcacaacatc tcatcctaca aaagttaaga agccaaagct acttgatcat     2520

gcaaaatgca cttatatatt tgttacactg tattgcaaga tagcacacag aagttggctg     2580

cgtcaagtag aggcgacatt tattaagtga aaatcatgga gttgggatat ctctcaatta     2640

aagaaataca ttgtgaacta tcagctacaa agttgtactg aataactatt agaattgcat     2700

aatgtgagat attttgttag tcctcaaaag gaatatcttg cagtgttttc tatgaaatgc     2760

ttgggcacaa acacttattt ctgtgaaaga gaacatgtaa gttgaggggt atgcttcatg     2820

ttcttccatc catttaccta atagtatgaa acagttcaca tttcaataaa atcaaacttt     2880

tcatgtagcg tatcacataa cttttttgca aaaaatataa aaagaaataa acttcaatgt     2940

attttttatt acaactttgt actggttgta acttgcatta gaaaaaaaag agatatatac     3000

accacaaaga atctaataag aaatttatta tggagatata gcccttaaaa tgcaatatta     3060

agaacaaaga aatagaaaat ggtttagata tctttcttcc ttcataatta aatactatat     3120

gaaacttgtg ccacagagct atatataata tgaaaagatt aacttcatag agatattgta     3180

agtaggtaat tttattattt aaagtcctat taagaaatat ttgtcttaaa tatataggac     3240

aatacattat attaaaatgg tctctctcta tatatatctg tatatcttat acatgtccat     3300

acacagaaac ataataaaca atcttcacac gaaaccaaaa atagcataca cctaatgttg     3360

ggttagggaa ttgcaatttc tactttcata gagtcataga attttaggtg gggaagaggc     3420

attttgcttg tcatttctta atataactca acaagaattg caacatttgt gtaccaagca     3480

ataagtgcaa tgcataaaat ttcctgtctg tatattacct tcattttgct tgtagtagct     3540

gtttgggtgg ttggaataat tttatttttc ttttaaaaaa gctaacatca gaccccttta     3600

taatgtccta aaattatgat aatacatttc ccaattcaac tcaaaatatt attggtgtat     3660

tttgtctatt ctggatattt gatctgttca atgtactgtg ctagtgactg gaggccctgc     3720

tactgcaaat ataaaacata aagtttgttt aaaaaaatgc aaatcattct ttaccttaag     3780

aaaaaaaaaa taccctttgc tttgtgcctc aaagtgatgt aatgtgatca cagcttttgt     3840

tgtgttgaat gaaaatatgt ggactgtcat tttgttgcag caaaaaagtg ttaataaaat     3900

gctctattta tccttttttt aaaaaaaaaa aaaaaaaa                             3938


<210>  2469
<211>  3938
<212>  DNA
<213>  homo sapiens

<400>  2469
cgtttaaaag ccatcagatt tgagagcaat aagtcttcaa aaccgggaat ttacattgtt       60

tttcagctga ccgacttcca ggaaaaggac tcaaccgcat ctacccaaat accgtggcac      120

tgcttgcgct ctttgccacc ggatcctccc cttccaatga gactttctga ttgtgtctac      180

caactctcct attaggaaac ccgtgggttg catgcagcta ttctgttgta ttctcattct      240

cactctccct cccttctctc actctcactc ttgctggagg cgagccacta ccattctgct      300

gagaaggaaa agcccgcaac tactttaaga gattaagaca atatgcgcaa tcctcgcctt      360

tcctagcaat cactatttaa atctggcaag aactgacaac agtctttgca agaatggaat      420

ccgtaaaaca aaggattttg gccccaggaa aagaggggct aaagaatttt gctggaaaat      480

cactcggcca gatctacagg gtgctggaga agaagcaaga caccggggag acaatcgagc      540

tgacggagga tgggaagccc ctagaggtgc ccgagaggaa ggcgccgctg tgcgactgca      600

cgtgcttcgg cctgccccgc cgctacatta tcgccatcat gagcggcctg ggcttctgca      660

tctccttcgg tatccgctgc aacctgggcg tggccattgt ggacatggtc aacaacagca      720

ccatccaccg cgggggcaag gtcatcaagg agaaagccaa attcaactgg gacccggaaa      780

ccgtggggat gatccacggt tccttctttt ggggctacat catcactcag attccgggag      840

gctacatcgc gtctcggctg gcagccaaca gggttttcgg agctgccata cttcttacct      900

ctaccctaaa tatgctaatt ccatcagcag ccagagtgca ttatggatgt gtcatctttg      960

tcagaatact gcagggactt gttgagggtg tgacctaccc agcatgtcat gggatatgga     1020

gcaaatgggc cccacctcta gagaggagta gactggcaac cacctccttt tgtggttcct     1080

atgccggagc tgtgattgca atgcctttag ctggcattct tgtgcagtac actggctggt     1140

cttcagtgtt ttatgtctac ggaagctttg gaatggtctg gtacatgttt tggcttttgg     1200

tgtcttatga aagtcctgca aagcatccta ctattacaga tgaagaacgt aggtacatag     1260

aagaaagcat tggagagagt gcaaatcttt taggtgcaat ggaaaaattc aagactccat     1320

ggaggaagtt ttttacatcc atgccagtct atgcaataat tgttgcaaac ttctgcagaa     1380

gctggacttt ttatttattg cttattagtc agccagcata ttttgaggaa gtctttggat     1440

ttgaaattag caaggttggt atgctatctg ctgtgccaca cttagtaatg acaattattg     1500

tgcctattgg gggacaaatt gcagattttc taagaagcaa gcagattctt tcaactacga     1560

cagtgagaaa gatcatgaat tgtggtggtt ttggcatgga agccacactg ctcctggtcg     1620

ttggctattc tcatactaga ggggtagcaa tctcattctt ggtacttgca gtgggattca     1680

gtggatttgc tatatctggt ttcaatgtta accacttgga tatcgctcca agatatgcca     1740

gtatcttaat gggcatttcg aatggtgttg gcacattgtc aggaatggtt tgtcctatca     1800

ttgttggtgc aatgacaaag aataagtcac gtgaagagtg gcagtatgtc ttcctgatcg     1860

ctgccctagt ccactatggt ggagttatat tttatgcaat atttgcctca ggagagaaac     1920

aaccctgggc agacccggag gaaacaagtg aagaaaaatg tggatttatt catgaagatg     1980

aactcgatga agaaacaggg gacattactc aaaattatat aaattatggt accaccaagt     2040

cttatggtgc cacaacacag gccaatggag gttggcctag tggttgggaa aagaaagagg     2100

aatttgtaca aggagaagta caagactcac atagctataa ggaccgagtt gattattcat     2160

aacaaaacta attactggat ttatttttag tgtttgtgat taaattcatt gtgattgcac     2220

aaaaatttta aaaacacgtg atgtaaactt gcaagcatat caaccaggca agtcttgctg     2280

taaaaatgaa aacaaaacaa acccatgagg ttaccatcaa gtgcaatctg taaaattgtg     2340

aagttccatc atttccattc aagtcatcca ttcttgcatt tgtgacttaa aggttgactg     2400

gtcaaaattg tagaaacaag tagttaccca ttggattcat atgagctaaa actcatcact     2460

atttactaaa gcacaacatc tcatcctaca aaagttaaga agccaaagct acttgatcat     2520

gcaaaatgca cttatatatt tgttacactg tattgcaaga tagcacacag aagttggctg     2580

cgtcaagtag aggcgacatt tattaagtga aaatcatgga gttgggatat ctctcaatta     2640

aagaaataca ttgtgaacta tcagctacaa agttgtactg aataactatt agaattgcat     2700

aatgtgagat attttgttag tcctcaaaag gaatatcttg cagtgttttc tatgaaatgc     2760

ttgggcacaa acacttattt ctgtgaaaga gaacatgtaa gttgaggggt atgcttcatg     2820

ttcttccatc catttaccta atagtatgaa acagttcaca tttcaataaa atcaaacttt     2880

tcatgtagcg tatcacataa cttttttgca aaaaatataa aaagaaataa acttcaatgt     2940

attttttatt acaactttgt actggttgta acttgcatta gaaaaaaaag agatatatac     3000

accacaaaga atctaataag aaatttatta tggagatata gcccttaaaa tgcaatatta     3060

agaacaaaga aatagaaaat ggtttagata tctttcttcc ttcataatta aatactatat     3120

gaaacttgtg ccacagagct atatataata tgaaaagatt aacttcatag agatattgta     3180

agtaggtaat tttattattt aaagtcctat taagaaatat ttgtcttaaa tatataggac     3240

aatacattat attaaaatgg tctctctcta tatatatctg tatatcttat acatgtccat     3300

acacagaaac ataataaaca atcttcacac gaaaccaaaa atagcataca cctaatgttg     3360

ggttagggaa ttgcaatttc tactttcata gagtcataga attttaggtg gggaagaggc     3420

attttgcttg tcatttctta atataactca acaagaattg caacatttgt gtaccaagca     3480

ataagtgcaa tgcataaaat ttcctgtctg tatattacct tcattttgct tgtagtagct     3540

gtttgggtgg ttggaataat tttatttttc ttttaaaaaa gctaacatca gaccccttta     3600

taatgtccta aaattatgat aatacatttc ccaattcaac tcaaaatatt attggtgtat     3660

tttgtctatt ctggatattt gatctgttca atgtactgtg ctagtgactg gaggccctgc     3720

tactgcaaat ataaaacata aagtttgttt aaaaaaatgc aaatcattct ttaccttaag     3780

aaaaaaaaaa taccctttgc tttgtgcctc aaagtgatgt aatgtgatca cagcttttgt     3840

tgtgttgaat gaaaatatgt ggactgtcat tttgttgcag caaaaaagtg ttaataaaat     3900

gctctattta tccttttttt aaaaaaaaaa aaaaaaaa                             3938


<210>  2470
<211>  4335
<212>  DNA
<213>  homo sapiens

<400>  2470
acgtaccagg gctcattgcg tgacggttac acttccggcg ggctacgtgc gcgcggcgag       60

cgccgggcgt acttttgcgt ggttgctcca ccccctcagc cttgccttcg ccgccgttgg      120

ggctggaagt tcccgccagg tccgtgccgg gcgagagaga tgctgcccgg cccgcctcgg      180

ctttgaggcg agagaagtgt cccagaccca tttcgccttg ctgacggcgt cgagccctgg      240

ccagacatgt ccacagggtt ctccttcggg tccgggactc tgggctccac caccgtggcc      300

gccggcggga ccagcacagg cggcgttttc tccttcggaa cgggagcgtc tagcaaccct      360

tctgtggggc tcaattttgg aaatcttgga agtacttcaa ctccagcaac tacatctgct      420

ccttcaagtg gttttggaac cgggctcttt ggatctaaac ctgccactgg gttcactcta      480

ggaggaacaa atacaggaat agcaacaact ataactacag gattaactct gggaacgcca      540

gccactacat ctgcagctac aacaggcttc agtttaggat tcaataaacc tgcagcatct      600

gccacaccat ttgctctacc tattacctct acctcagcta gcggtctgac tctttcgtct      660

gctctgacat caactccagc agcatccaca ggatttactc taaataattt gggtgggaca      720

acagccacaa ctacaactgc atcaacaggc ctctctttag ggggagcctt agctggtttg      780

ggaggttcac ttttccagag tacaaacaca ggaacatcag gacttggaca gaatgcttta      840

gggttgactt tgggaactac agcagctact tcaactgcag gcaatgaagg ccttggtggt      900

atagatttca gtagctcctc agataaaaag agtgataaaa cgggaacaag accagaggat      960

agtaaagctc tgaaggatga aaatctacct cctgtcatct gccaggatgt tgaaaatctc     1020

cagaaatttg tgaaggagca gaaacaagtt caagaagaaa ttagtagaat gtcttcaaaa     1080

gcaatgctta aggtacaaga agatattaaa gctctgaagc agctcctgtc gttggctgcc     1140

aatggaatac agagaaacac tctcaacatt gacaaattga aaatagaaac tgctcaggag     1200

ttgaagaatg ctgaaatagc tttaagaacc cagaagacac cacctggact tcaacatgaa     1260

tatgcagctc ctgctgacta cttcagaatc ttggttcagc aatttgaggt acagcttcag     1320

cagtacaggc agcagattga agaactagaa aaccatcttg ccactcaagc aaataattca     1380

catataaccc ctcaagattt gtcaatggct atgcagaaaa tttatcaaac atttgtagct     1440

ttagcggcac aacttcagtc tattcatgaa aatgtaaagg ttctgaaaga acagtacctt     1500

ggctacagga aaatgttctt gggagatgct gttgatgtgt ttgaaacaag gcgagcagaa     1560

gccaagaagt ggcagaacac acccagagtt actactggac ccactccttt cagcaccatg     1620

ccaaacgcag cagccgttgc catggctgca acacttacac agcagcaaca gcctgctaca     1680

gggccacagc catctctggg agttagtttt ggaacgccat tcggctcagg tattggcact     1740

ggcttgcaat caagtggctt aggttcttca aaccttggag gatttggaac tagctctggt     1800

tttggatgca gcaccacagg ggcctccaca tttggatttg gaacaacaaa taaaccctca     1860

ggaagtctta gtgcaggctt tggcagctca agtacatctg ggtttaactt cagcaatcct     1920

ggcatcacgg catcagctgg tttgactttt ggggtgtcca atcctgcctc tgcaggtttt     1980

ggaacaggag gacaactcct tcagttgaag aaacctccag ctggaaacaa aagaggaaaa     2040

agataaacat gggttgatgt gttgagagaa tccatagcag caccgttcat tctatgagtc     2100

tatttttcta atgatgcagt aattaaattg catcccagga gatttataaa gttttgatat     2160

ttttccctac tctggaattt gaactttctt catgtttgcc atactgaaca tcttttttct     2220

tgtggaattt aaagtccagc tgtgttttct ttttaatttg attctcagtg taagaaatgt     2280

tctgattaca tcactgattg gtaatggtta gaaaccatta acctaaaact tactatttaa     2340

cctagtgttt ttgttgatga ggtttacatt atgtgaatac atgcacattt gtttcttata     2400

caggtggtgt gaactctagg gcctatacta gaatcaattt gttccttgtt aaaggccttt     2460

tgaattatac tgcagggcat cttgtgaata tgtatgtaaa tatatacaga ataatacaca     2520

cagttgtgtg tgcatataaa atacatattt acgccaggcg tggtggctca cgcctgtaat     2580

cccagcactt tgggaggccg aggcaggcgg atcacctgag gtcaggagtt tgagaccagc     2640

ctgacatggt gaaaccccat ctctacgaaa aatacaaaaa ttagctgggc atagtggcgg     2700

gtacctataa tcccagctac tcgggaggct gaggcacgag aatcacttga agccgggagg     2760

tgggggttgc agtgagccga gatcacacca ctgcactcca gcctgggcaa caagagcaaa     2820

actccgtctc aaaaaagatg aaaataaaat aaaatatata tttacaggcc tacaactttt     2880

gcctcagact gttccccttt tctaagggta ttcaagtttt caccttttaa gcttcatatc     2940

ctcagtgctt gtagaatgat gagcttagag gtaccaggtc attgcagttg tttgcttaaa     3000

gacttattga aatggttact ggcgtaaata cttggccaac tcaactttat tgcccctgat     3060

cttttccatt tttgtttcca ccttaaccta tagcagctcc tccaaatgag gaatgctgta     3120

agtaagactc atcaaacaga ttttaaccat tttattatcc tgtgtgtcct tacattgctt     3180

ctgtgagatg tttttttctt atctgagatg aactttcagg agcctatttg aactccagac     3240

tggtgttctg gggcaaagag ctattagcca aactgattct atgcaggtga aggatgcact     3300

aaagttctca ctttagtgag aacttttcta gctattccaa tacagagttc tttcttatag     3360

ggctattgat attgacacca aatggagtgg cttctcagcc tcttaatgtc ttaagtaagt     3420

gcttaatttg gaatagagaa accagtatat tttaaaaaag aaaaatattc tttgtagcaa     3480

ctgtaaattc tcccattata acagtgaaca gagctccagg taataacgca taggcatgtc     3540

aggttgcatc tgtatatttg actacattag tattagtgac atcaggtgga tataaaagaa     3600

aacccttgga aagagaactg ccttagccat gatttcgtta gtagacctat ttatgattca     3660

attgcaattt tcagatagga tgtgaacatg gaatttcatt gaaaatagtt taatttttta     3720

tataaaaggt tttgtatata atgtgtgtca gtgactattt tcaaaatcat tttcatcaag     3780

acaccttttt tctaaaatag gcattgcata cacatatgca cacgtatgtg catgtgccac     3840

acattttttg tataatgttg ggtttgatta taaaagtgtt gtcaaatgtt ttatttatct     3900

gcatatagca gtggttggct tttttgaatt gaaatttttg cgcattgatg cattgaaata     3960

aggaaaatta tttatctctg agcactaaac ttatttttgc atatttctgt aatattgcag     4020

tccccagatc cagaacatgg gaagttaggg aaaatgtgtg attttgtgtt ttgaattact     4080

gtcagaatta catacacaat tacaacaaac tttttttaaa agacatttca ttgtactgca     4140

aaaatctgaa tatttatatt tcttgttttt ttctttatat gttttgcatt ttaatatgtt     4200

gagccactgg aaatttgtaa cagattaatt tgttatagga gtttaaatgt gttgtcattg     4260

tctccattgt ctttgtccag agcctattat tatggaaaca ataaaattta ttgtgtcagt     4320

tgctttgatt cttta                                                      4335


<210>  2471
<211>  1588
<212>  DNA
<213>  homo sapiens

<400>  2471
ggcgcctgcg aacccgggcc cgggggggac ggcgcccgcc aggagcgccc cccactccca       60

ggccagccca ccccggcgga ccgggccccg cgcgcccagg cgaggtgagg cccgcgccgt      120

cagggctgcg tgtcgccccg cgcccctgcc cagcccgcga ggactgcccc ctcccccggc      180

gcccgccccc acccccgcgc cccaggtgag ccccggagtc caggtaaggc tccgcgttgc      240

aggtaagagc ccctgagcgt agaggaggcc ttggcgcccg caggtgagag cccctcccct      300

cctaggtgac cctcaacctt cacggcgagg cctcctacct cctccaggtg ggggaccctc      360

tccccgatga accccctaaa ccaccagtga accccactgc tctccagatg aggtcgcaag      420

gaccaaccag tgcctacccg cccatgctcc cccgaaactg ggaactgaca gcccagcccc      480

tccaaagccc cttcctccag cttcagctgc caggtcagca agggtgaggc cggaagcagg      540

cgggtgactc accctgggca cctccgagcc tcagtttccc catggatgca acctgaggcc      600

tcctcactga gtcaaaaccg agacgcctct ggtccccgga gaggctgctg gctctgggga      660

aaggagagag cagcccagtg tgacagagcg agtccccacg gctctgggag tgcctcgcat      720

gtgtgtggcc caggtcctga cagcccacct actccctccc cggcaggcac tgggctccct      780

ctgctccccg tgggccgctc cccgcgtggg gccactgccc ccggcccccg ccatggtgcg      840

gatttcaaag cccaagacgt ttcaggccta cttggatgat tgtcaccgga ggtatagctg      900

tgcccactgc cgcgctcacc tggccaacca cgacgacctc atctccaagt ccttccaggg      960

cagtcagggg cgtgcctacc tcttcaactc agtggtgaac gtgggctgcg ggccagccga     1020

ggagcgggtg ctgctgaccg gcctccatgc tgtcgccgac atccactgcg agaactgcaa     1080

gaccactttg ggctggaaat atgaacaggc ctttgagagc agccagaagt acaaagaggg     1140

gaagtacatc attgaactca accacatgat caaagacaac ggctgggact gacccccgct     1200

cccccgacgc atgtggctcc agcccggcct ggccgccagg gagcgccact ggcttcccgc     1260

cacccgaagg gagctctgga ccctcagagc ccctgcagag gacggatcta gctcctgtat     1320

atatatttta ttgcatgcac tgtgaccttg gggggagaac agaaggggga cgacgccccc     1380

gcacctcctg cgatctggct ggcttggatc tcgtttttaa cccgttcctg ccccacctgc     1440

cctatagtta tggcctgtgt tctgctctcc tggtcccagt gcaccgtctg ctctgtgaac     1500

tcctcccacc aggcccttct taccccacgc gtgtctgtcc ccctcgttct gtagcgtttg     1560

tacataataa aacaatggag tggagaca                                        1588


<210>  2472
<211>  1096
<212>  DNA
<213>  homo sapiens

<400>  2472
agacccgccc gcccgagccg gagttacaag agccgcctcc gcgcacgggg gcccggccac       60

tcggagctgc tctgccgcgg ggactgcacc gcccgccctg ccagacccgc ccggaacggg      120

gctcgtcgcc gccagtagcc gcagcaccgc agccttgggc ctcgcgccgg ctatggccgt      180

gccctggggc tgagccctca ggttgtgacc gagattcccg acgagagaga ctgaggggaa      240

gagaggaagg aggggcgggc tcctggcaag gcattcgctc ctgagcggaa tcctgcaaag      300

atggagaagg aggagacaac ccgggagctg ctgctgccca actggcaggg tagtggctcc      360

cacgggctga ccatcgccca gagggacgac ggcgtctttg tgcaggaggt gacgcagaac      420

tcccctgcgg cccgcactgg ggtggtcaag gagggggacc agattgtggg tgccaccatc      480

tactttgaca acctgcagtc gggtgaggtg acccagctgc tgaacaccat ggggcaccac      540

acggtgggcc tgaagctgca ccgcaagggg gaccgctctc ccgagcctgg ccagacctgg      600

acccgtgaag tcttcagctc ctgcagctct gaagtggttc tgaacacacc acagccatca      660

gcactggaat gcaaagacca gaacaaacag aaggaagcca gcagccaagc cggggcagtt      720

tcagtctcca ccccaaatgc aggactgtag aagcggccag gaagaaaacc accccctctt      780

aaggttgttt ttgtgaccgt tctttggagc attgttctaa aaatgggaaa ttacatattg      840

ctgtgccaag ggcaacaaac acctgcagtt aaaggaatac cttccgcgag gcggcttttc      900

ggagcatgca tgtttatagc tccagccagg ccagaccgag ggctgctgca taagccctgc      960

ttggtgcatt tctttacttg caaggggaca gagtgtgggc ttaggtttgg gactagaggg     1020

ggctttggca actatggtgc tcaggtgatt atccttcgct cgtttatcca ataaacattt     1080

atcaagcatc tgaaaa                                                     1096


<210>  2473
<211>  3579
<212>  DNA
<213>  homo sapiens

<400>  2473
gctttgggca tccttgaaaa gaatcttctg aggcctcagc attttatctg agtcttctga       60

atcccactta gaactgtgtt gagctctcac ccatcacgat gagcaacaaa ttcctgggca      120

cctggaaact tgtctctagt gagaactttg acgattacat gaaagctctg ggtgtggggt      180

tagccaccag aaaactggga aatttggcca aacccactgt gatcatcagc aagaaaggag      240

atattataac tatacgaact gaaagtacct ttaaaaatac agaaatctcc ttcaagctag      300

gccaggaatt tgaagaaacc acagctgaca atagaaagac caagagcatc gtaaccctgc      360

agagaggatc actgaatcaa gtgcagagat gggatggcaa agagacaacc ataaagagaa      420

agctagtgaa tgggaaaatg gtagcggaat gtaaaatgaa gggcgtggtg tgcaccagaa      480

tctatgagaa ggtctgaaaa atcatttctt cattgaagtg gctttttatc atttaatgat      540

ggaaatcaat tgcttccatt gacaaaactg aatacactgc aaatatttgt ttttgctttt      600

gtcttaatat atcagatatg caaaggccta aactgagaat taatctaaaa gtcagtgtta      660

tttaaacatt ttcaatgtgc atgcatgtca ttattacatc aaagcatata tattggccag      720

acacaaacag ttgatgatgt cattcaatta actacaaaat tctaatctat gttgaacttt      780

gtatacttga aatgataata aaaaggatat aatttcttag taaaatgaaa tcaaagtatt      840

gatcagggta gcaaactcaa atgctgacag gggccagagg agatatgggg aaggagcatc      900

agaaatgagg caagctagga gaatgggcta ttataatgta aagaattgta gtctcagtta      960

aaaggggtag cctctactcc agccaacatt ttaaaattaa tggataattt atagacagtt     1020

aaatttatag acagttaagt aaaaatggat aatttataga cagataattt atagacaggt     1080

aaatgtgagt taaatataac tcacatccca ctcaagacac aaaacatttt cttaatccta     1140

gtacattttt ttctgtccct tcccaatcag tgtccttttc tgttccaccc ctaccaaaag     1200

caagtagtgg tttggtttct atcatataga ttaattttac ctgctcatat gaagggaatt     1260

gtacatcatg cattcttttc tgtttgcctt ttttaaattc agcatcatgt ttttgtgata     1320

catccacatt gttgcatgca gctgtagttt gtttcttttt attaccaagt actatttcat     1380

tgtatgaata tatcacagtt tatccattct actattaaga caattgagct atttctaatt     1440

ttcggctgct atgaataaag ctgctacaaa tatttttgta caagactttt tgtaaacata     1500

ggagtccctt tattttaaat aaataactag tcatatcatt aggtccagta attgttgaca     1560

ggcaggaacg ggggaccatt gcattgtgcc caagtaataa taaaactatt tcagatgtat     1620

tatatgattg agcaaatgag aaaacatgtt gatgttgatg ggagtcagga tgttcactat     1680

ggaaaaacaa atatacaaat atgaaatgag ggaaggcaag aaagaaccat gtggaaatgg     1740

aatagaattg gtataaattc ataatttcta aaccatgtat atgtacgttt atatgtatta     1800

taattgcata cacatgcctc catgcatata tgtgtgtgat aatacacatg catttatgtg     1860

cgtgtgtgta tacacatgca tatatttact aatcctatct gccaaaatgg cttagacaca     1920

aaaacacctc agcagaaatg aatataccta gcactcagat cttcgtgtct aatatagttt     1980

gccactaaaa ggaaccaagg ctacttggaa aaatggatga ttccaaagca agggcaaggt     2040

aggaacaaga tgagcttgaa atatcttgtt atgccagaaa gtaatgttaa aaaaaaaaat     2100

agaggtatat tgccaaaaca tagagccagc ttgaaggggc tcccactggc caaacttgag     2160

ccaatctgag agcaaaataa ttgagaaaaa taaataacaa gataattgag aaaaaaataa     2220

aataaattcc caattccatt gggaaaaaat agaaatccat gaatccatac tgatataatg     2280

atagataatc gatagatagg tagatgactg acagatgata gatagatata tagatagata     2340

gatagataga tagatagata gatagataga tagagaaatg agaaggtttc tcttttgcaa     2400

tagaacgtca tggaccagtg ttaaatgtga gtggaaggag ttctggaatt ggaaaaccat     2460

catttttcaa ccatcacagt aaatatggct caggcaagaa ttatcaatca atgctaaagc     2520

tagggggaaa tttcgcttag gagcaggata ttagggtatt agtctgggct taaagtatct     2580

cctcacagat tgttgttagt ttctggggaa agaatagtaa ccatgcaatg gaaaaaaatg     2640

gacaacctct tgactaggtt atcaaaatta acctcaccaa taaagggtgg atgttcaaca     2700

tgtgccttca aatgtgaccc actgagaagg aaacaacatc actgtaacaa caacaaccag     2760

aaacgacagg gggttttgac tgaattcttc aaaaatgtca atgtcataga agacaaagaa     2820

aggttgtgga aatgtttcag attaaatgat agtaaaaaca cctgacaact aaacatagta     2880

agtaatacta gactggattc tgtaccagag gtaacataag tgctccaaag gacaatgtta     2940

ggtcaactgg caaattggaa tatagacagt caatcagata agaagtatac tttgattaag     3000

taaaaaaaat ccctattctt ggaaaataca caataaagta ttttgaggta aagggccata     3060

atgtatgcaa tctactctca aaaaattcag aaacatatat ttgtgtgcat ttgcatgtgc     3120

aacagtacac acaaacatac ataaagagag caattgataa ggcaaataag gtaacattta     3180

acaataatct gatacacata aatagagaaa gagcaattga taaagtaaat gaggtaaaat     3240

ttaacaataa tctgagcaaa aggtatatgt gttttctttg agacagtctg attcttgcaa     3300

cttattctgt aagttggaac ttatttccaa acatgattga aaaaaaaccc cgcacttggc     3360

aacttcttct ctttttcagc ctagaaatgt ctgtgttaag tggtttttta tttattgttg     3420

ttgtttgttg ttattgttgt tttgttgcca ggctccaact cacaaaatac gagtttaaaa     3480

actgcgttgt tatttttaga gatttgtgat aatacaactt gttataaaat ttattcctca     3540

ataaatataa tttctctact atgcaaaaaa aaaaaaaaa                            3579


<210>  2474
<211>  4193
<212>  DNA
<213>  homo sapiens

<400>  2474
gttgtcagtc cgatctcgcg agagaggacg gaagcctgtg ggagcccgtg gcctttaaag       60

tgccgttcag ccttttcctc caggggtgct ttgtaaacac ggctgtgctc agggctcgcg      120

ggtgaccgaa aggatcatga actagtgacc tggaaagggt actagatgga aacttgagaa      180

aggactgctt attgataaca gctaaggtat tcctggaagc agagtaaata aagctcatgg      240

cccaccagct agaaagtatt cttgccatga gaaaaagaat gtgataagtt attcaactta      300

tgaaattcaa gttacatgtg aattctgcca ggcaatacaa ggacctgtgg aatatgagtg      360

atgacaaacc ctttctatgt actgcgcctg gatgtggcca gcgttttacc aacgaggatc      420

atttggctgt ccataaacat aaacatgaga tgacactgaa atttggtcca gcacgtaatg      480

acagtgtcat tgtggctgat cagaccccaa caccaacaag attcttgaaa aactgtgaag      540

aagtgggttt gtttaatgag ttggcgagtc catttgagaa tgaattcaag aaagcttcag      600

aagatgacat taaaaaaatg cctctagatt tatcccctct tgcaacacct atcataagaa      660

gcaaaattga ggagccttct gttgtagaaa caactcacca ggatagtcct ttacctcacc      720

cagagtctac taccagtgat gagaaggaag taccattggc acaaactgca cagcccacat      780

cagctattgt tcgtccagca tcattacagg ttcccaatgt gctgcttaca agttctgact      840

caagtgtaat tattcagcag gcagtacctt caccaacctc aagtactgta atcacccagg      900

caccatcctc taacaggcca attgtccctg taccaggccc atttcctctt ctgttacatc      960

ttcctaatgg acaaaccatg cctgttgcta ttcctgcatc aattacaagt tctaatgtgc     1020

atgttccagc tgcagtccca ctcgttcgac cagtcaccat ggtgcctagt gttccaggaa     1080

tcccaggtcc ttcctctccc caaccagtac agtcagaagc aaaaatgaga ttaaaagctg     1140

ctttgaccca gcaacatcct ccagttacca atggtgatac tgtcaaaggt catggtagcg     1200

gattggttag gactcagtca gaggaatctc gaccgcagtc attacaacag ccagccacat     1260

ccactacaga aactccggct tctccagctc acacaactcc acagacccaa agtacaagtg     1320

gtcgtcggag aagagcagct aacgaagatc ctgatgaaaa aaggagaaag tttttagagc     1380

gaaatagagc agcagcttca agatgccgac aaaaaaggaa agtctgggtt cagtctttag     1440

agaagaaagc tgaagacttg agttcattaa atggtcagct gcagagtgaa gtcaccctgc     1500

tgagaaatga agtggcacag ctgaaacagc ttcttctggc tcataaagat tgccctgtaa     1560

ccgccatgca gaagaaatct ggctatcata ctgctgataa agatgatagt tcagaagaca     1620

tttcagtgcc gagtagtcca catacagaag ctatacagca tagttcggtc agcacatcca     1680

atggagtcag ttcaacctcc aaggcagaag ctgtagccac ttcagtcctc acccagatgg     1740

cggaccagag tacagagcct gctctttcac agatcgttat ggctccttcc tcccagtcac     1800

agccctcagg aagttgatta aaaacctgca gtacaacagt tttagatact cattagtgac     1860

ttcaaaggga aatcaaggaa agaccagttt ccatttatgc gaaatctgtg gttgtaaatt     1920

tttttttttt acttgaaatt aaatttggct ctaaagttgg tgtagcagca gttgatcaga     1980

ctgaaaaacg gtttttagtc tctggaaaaa gactgatttt gcttttttta taaatattat     2040

tagatttatt aatttttctg tgctcaatgt gtaaattgta ttataattca ttgtgattta     2100

tttcactttt aatttgctgg tgttttaata aatgggggtg ttactgaatc tttcttccca     2160

cttccatttc ttttgaccac cccttaaccc tcaactgtga cggtagtagt attatcattt     2220

ataccaaagt tttgcatagt ccctgttgac tttgtaatgt taacggagtc ataaaagcac     2280

taggcaagag aaagatagaa atttgctttt aatctttttg ccttttattt tgcacattat     2340

gcaaaaggaa aaacattaaa gaacactttt ttttaagtga gtgaaaacat ggtaaagaca     2400

tacagtgctt ttatgcacat tgttaagcta aatcaaggtc atttataatc attttccttt     2460

tttatttaag attttaagta aacaaatttt agaattttca gcatttcaaa aatgatttta     2520

tttttcaagt cttaaattca atattttaca cctatgtttt gaggctaaaa atatgaaatt     2580

atataatgta tgatacaggg ttatcaaata tctaataatt tttgaaatta gctcttgttt     2640

ttggtttttt tgttgttgtt tttacagatt tcaggttaca aactgcaaag tttatgcata     2700

attaagtatg gtatggttgc cagaaaagcc taaaattact acttagaaaa tttaagactg     2760

tttaccccca ttgtcttgta cttgcgagct aacttgtact attcttgtga aagcactgtc     2820

atcttttagt agcaaatttt gataatgttt ctcgtggaaa aaaaaatcag tatctatctt     2880

tagaacaatg taattataat gtgggaagtg tgcatgaatg agagagagtg tgtgtgtatc     2940

tgtgtgtgtg tgcgcgtgtg tgtgtgtctt ttaatagttt atgccagcaa tctttgcttg     3000

aatgtttaac gatgccttca gtgtgatgct ggccaataga tgattgcagt ttaaaatgtc     3060

attattgtgc aggcttggat aactaacatt ccatgatgta gcttgtttct gatgagatga     3120

ttgtaggtac atttttctca ttatccaatc atctgtggga tacttagttt tctaatgtgc     3180

cattatctat ttttattctg cagttatgtt caaaatacag tacatatttt aaaatagaat     3240

aaattgttaa acataaaatt ttaaaagtag tagatgtgcg taagaaaact ttgtaaaata     3300

gttatgagtc ctacccagta gcaacttctg gcattcaagc aggattccac tatgtaaata     3360

tctgtaatgc atttataata agttgtgtag tttgtcctgc atccatacta cactatttgc     3420

taaagtctca gtgccatctc ctaatgagac tgacatttta aaagtctgta tggaatatcc     3480

ttgataattc aaggaaatat ccctcctgcc taagttccaa actgggaaac attcaaatta     3540

tataaatgac atttcaggac tttaagtatg aagataatgg gaattttatt gttttgcttt     3600

ttaaaatgag agcattttta tttgataatt ttttttaaat ttttaatttt taactaattt     3660

cattatttta aagtaatcag tttttcaaat catgattttg atatcattat tctaaggagt     3720

tatctcaaag gcacaaaata tgaattctgc aagaaggcta ttttttattg tagtttgaat     3780

gggttaggaa aagcctcaat ttttcactct taagtccttc agtacatttt tctttcatct     3840

tattacttat gcaagttaag gttctttggt aacagaattc ttgcaactgt aaaataaaac     3900

tacatagatg taagaagtca tgtaaacggt taacaagctt accaaggtta gcaaaacttt     3960

cattgtaaat cagtctgtac tgagcaaata aaaatcatta ttagttgtat aaacacaaat     4020

tccattttga ctttcaggat gtcatactac ttctgtacct agcattttca gtccttatat     4080

ttgcaatgtt acacaaactg tactattttc ttttatgtgc agtttgcatg agtaaaccat     4140

cagagaataa attctatctt taaattatgt tcataaaaaa aaaaaaaaaa aaa            4193


<210>  2475
<211>  3512
<212>  DNA
<213>  homo sapiens

<400>  2475
agaaaggcgc gcgaaggcgc ggaggaggcg tcggctgcgg cgcccactcc ccctagtccc       60

agcgccctgc cgctcgcctc ccgctgccgg gcgccggcgc gctcggctct ttccgccgcc      120

gccgctgccg cgcggtggcc cgtgcgcctc ggcaccttcg gcaatttccg tcgggcccca      180

gccgccattt tctcgccgct tgtgtggctc gctggctgcg tggctcggtt cttgtgagcg      240

aagctttgtc cggttcggca atggacggaa tcgtcactga ggttgcagtt ggcgtgaaga      300

gaggatctga cgaactactc tcaggcagtg ttctcagtag tccgaactct aatatgagca      360

gcatggtagt tacagccaat ggtaatgata gtaaaaaatt taaaggagaa gataaaatgg      420

atggtgctcc ttctcgtgta cttcatattc gaaaattacc tggggaagta acagaaactg      480

aagttattgc tttaggctta ccttttggta aggtgaccaa catccttatg ctgaaaggaa      540

aaaatcaggc atttttggaa ctagcaaccg aggaagcagc tattactatg gttaattact      600

attctgctgt gacacctcat cttcgtaacc aaccaatata tatccagtac tcgaatcaca      660

aagaactaaa gacagataat acattaaacc aacgtgctca ggcagttctt caagctgtga      720

cagctgtcca gacagcaaat actcctctta gtggcaccac agttagcgag agtgcagtga      780

ctccagccca gagtccagta cttagaataa ttattgacaa catgtactac cctgtaacac      840

ttgatgttct tcaccaaata ttttctaagt ttggtgctgt attgaagata atcacattta      900

caaaaaataa ccagtttcaa gctttgctcc agtatggtga tccagtaaat gctcaacaag      960

caaaactagc cctagatggt cagaatattt ataatgcctg ctgtacccta aggattgatt     1020

tttccaaact tgtgaatttg aatgtaaaat acaacaatga taaaagtagg gattatactc     1080

gacctgatct tccatctggg gatggacaac ctgcattgga cccagctatt gctgcagcat     1140

ttgccaagga gacatccctc ttagctgttc caggagctct gagtcctttg gccattccaa     1200

atgctgctgc agcagctgct gcagctgctg ctggccgagt gggtatgcct ggagtctcag     1260

ctggtggcaa tacagtcctg ttggttagca atttaaatga agagatggtt acgccccaaa     1320

gtctgtttac cctcttcggt gtttatggag atgtgcagcg tgtgaagatt ttatacaata     1380

agaaagacag cgctctaata cagatggctg atggaaacca atcacaactt gccatgaatc     1440

atcttaatgg acagaaaatg tatggaaaaa ttattcgtgt tactctgtct aaacatcaga     1500

ctgtacagct acctcgagag ggacttgatg atcaagggct aacaaaagat tttggtaatt     1560

ccccattgca tcgttttaag aaacctggat ccaaaaattt tcaaaacatt tttcctcctt     1620

ctgccaccct tcacctatct aatatccctc catcagtagc agaagaggat ctacgaacac     1680

tgttcgctaa cactgggggc actgtgaaag catttaagtt ttttcaagat cacaaaatgg     1740

ctcttcttca gatggcaaca gtggaagaag ctattcaggc cttgattgat cttcataatt     1800

ataaccttgg agaaaaccat catctgagag tgtctttctc caagtcaaca atttaaaaat     1860

gggaagatga agattggggg tgaatcacat tgttcaatgt catcacctat ttgactgttc     1920

agaaaagtgg ggaccagagt ttgatttttt ttgtttttgt ttttttgggg tttctttttt     1980

ttttccatgc tgttatcatt ccttggttat aaaatgaaat ggcatatgta aaggcagagt     2040

tgttaactgc tatatttcat ctgttctata gggaagccat tttgtctgtt taaaatttca     2100

gtttaatttt gctttttttt tttttttttt tttcctttca acttagttga catacgtgcc     2160

ttaaaaagga aaactagtgt tgctattgtg catttactag aaaaaaggaa ttggttgttt     2220

agggcacact gttatatggg aattaaaata tgtttaggca ggggtgtgta aaaaggttaa     2280

gtttttgttt ctcctgcttg gaacttattt tgaattactg gcttgtcacc tttttttcta     2340

tttaatcaaa taagatacat gatattgaaa gaataaagca gcatttttag tttttactac     2400

cttaggcttt attgctttga aaacaacatt ggccttttgt atctcacaat tctggtctag     2460

attcagttat gaatgtaggc attagttaaa attaacaaga tgcagagtat taatttctta     2520

agacaacaaa gtgatttctg taagtttgag ccctatgtgg aaagcattgt ggaatcttaa     2580

ccttttcgta cacactcttg tgggacgtat catataaatg tcagcactaa gtaatgtctt     2640

gtttgtggct gaatattttt cgtagatgtt tttgaagttg acatgactta cgtgcattta     2700

aatatatatt gccatcctta gtttgtaatt aagatttgga atatggttgt ggatttctga     2760

gcatgtgcag actggtctag ctagttcagg aactggtgca tgtatttttc aaagataaag     2820

aaagtgtact gcgaaaatat gcaggaagat taattttgtg gcagttttct aaaactgaca     2880

accaggtggg accaaagttt atgtgccttt agtcttaatt taccttgcat tgtaatattc     2940

agttttaata aatcttcaaa atattttgta tttaggaata gatctgactt taataaaaac     3000

atggctcaga atctacaggt caaattaatt tgaacagttc ttgtcaatcc gaattgttga     3060

ttctgtttaa atgaccaata ctttttgaaa ttgatgtact tagtttcaag attcatagat     3120

tctgttatct atgtagacag aatggtcatg tatattttct attagttgag tttttacatc     3180

tttagaaatg taaaattcag tatagtttga aagcggcaca attaaaaatt aattttctaa     3240

caaagttggg aggtttgatg gttgtttaat ttcattttgt gtgtactctg cttacccctg     3300

tagcatgctc aataaacact tctgtagctc tatattcacc ttttctgtct ttctctgctg     3360

ccttttctct ctcctcttct ttgttttcac tccactgtgc ttctgaattc atgtttattc     3420

tctgccaggg tgggaaagga gtaataatat tacaattcta tggctttata ccataaataa     3480

atctagatgc tgtgaaaata aaaaaaaaaa aa                                   3512


<210>  2476
<211>  8235
<212>  DNA
<213>  homo sapiens

<400>  2476
ttttagtggt ggagtcaatt tatttctgaa acgatctcat ttacctgaat gaggagctca       60

tatttatttt caggatttat gaggaatcca agatgaattt ggagcaggag aggccgtttg      120

tctgcagtgc cccaggctgc tcccagcgct tcccaacaga ggaccatctg atgattcata      180

ggcacaaaca tgaaatgact ttgaagtttc cttcaataaa aacagacaat atgttatcag      240

atcaaactcc gaccccaacg agattcctga agaactgcga ggaggtgggc ctcttcagcg      300

agctggactg ctccctggag cacgagttca ggaaggctca ggaagaggag agcagcaagc      360

ggaatatctc gatgcataat gcagttggtg gggccatgac ggggcccgga actcaccagc      420

ttagcagcgc tcggctgccc aaccatgaca ccaacgttgt gattcagcaa gccatgccgt      480

cgcctcagtc cagctctgtc atcactcagg caccttccac caaccgccag atcgggcctg      540

tcccaggctc tctatcttct ctgctacatc tccacaacag acagagacag cccatgccag      600

cctccatgcc tgggaccctg cccaacccta caatgccagg atcttccgcc gtcttgatgc      660

caatggagcg acaaatgtca gtgaactcca gcatcatggg gatgcaaggt ccaaatctca      720

gcaacccctg tgcttctccc caggtccagc caatgcattc agaagccaaa atgaggttga      780

aggctgcatt gactcaccac cctgctgcca tgtcaaatgg gaacatgaac accatgggac      840

acatgatgga gatgatgggc tcccggcagg accagacgcc acaccatcac atgcactcgc      900

acccgcatca gcaccagaca ctgccacccc atcaccctta cccacaccag caccagcacc      960

cagcacacca tcctcaccct caaccccatc accagcagaa ccatccacat caccactccc     1020

attcccacct tcatgcacac ccagcacatc accagacctc gccacatccg cccctgcaca     1080

ccggcaacca agcacaggtt tcaccagcaa cacaacagat gcagccaacc cagacaatac     1140

agccacccca gcccacaggg gggcgccggc gaagggtggt agacgaggat ccggacgaga     1200

ggcggcggaa atttctggaa cggaaccggg cagctgccac ccgctgcaga cagaagagga     1260

aggtctgggt gatgtcattg gaaaagaaag cagaagaact cacccagaca aacatgcagc     1320

ttcagaatga agtgtctatg ttgaaaaatg aggtggccca gctgaaacag ttgttgttaa     1380

cacataaaga ctgcccaata acagccatgc agaaagaatc acaaggatat ctaagtccag     1440

agagtagccc tcctgctagt cctgtcccag cttgctccca gcaacaagtc atccagcata     1500

ataccatcac tacttcctca tcggtcagcg aggtggtagg aagctccacc ctcagccagc     1560

tcaccactca cagaacagac ctgaatccga ttctttaaaa tgcaccatca gacctggcct     1620

ccaagaagag ctgtagcgta ccatgcgtcc tttcttttaa gggcattttt agaattaact     1680

cagacctgga agactcctca gttcttcaaa gactggcttt catttttata gttattatgg     1740

aaatgttgtc ttttatactt agttatataa gaaaaaaggg agttatgcaa ttaatatcta     1800

tcagcttggg aaacgctttg gtgcttttct ccagttttct ggtaccagtt acttgtttat     1860

aaactgaacc ttttctgtat atagccatgg tttcattctt atcagtccaa ccctttgcct     1920

gaaacattga atcttgttaa accacagctt ttagctaaaa tgaggtatac ctagatgtca     1980

agtaagacag atccaaggta actgggtagg aaatcttttg acatcttaac tcatgttgag     2040

tttgtgctgt ggtgtcacca gaattccaga taaacacaca gcctttccca tacctttttt     2100

tttcttacta taaaatatta taagatccat tgatgtccaa ataataccac caagcatctc     2160

ttcacctctc ctcctcttgg tccacttgct aatgcccagt tttcttctcc atttccactt     2220

tttcttaggc tccctattta ctattcattt tgacttcctt ctgttttatt tttttccctt     2280

tagcattgca tgtgaataag aaaataatgt ttaaagaaaa aaaaaaaaaa gcaaacctcc     2340

aaaacgtgga cctaaccatt gcttcactta cacttcaccc acagctggag ttcattcaac     2400

tcttgctttt cacaaaatag taaccaggag atgtttaatg tgcctgattt aatgttttta     2460

ataatcacag caaatgaaag gtggtttagt tataagtgaa gcatggttga ataccagctg     2520

gggagacact agggaaggga gctttgtaag ccttgattgc gaaagtccaa attttgatgt     2580

ggggctataa catgacaccc ttggattgcg actggtttta tacggcctgc ctataacgtt     2640

gaaaatccat gtactacata ataattcaga agggctctat tcactacaca gattacattg     2700

ttcaatcatc agctgctaat agcctaagat ttattttttt ttttttctta agcctatgga     2760

accggctttg ctgttctggg gggtgaaaat agactaacta ctggagaaac aaagagagaa     2820

agaaaaccca gtgtttccat aggggcactt ttagccttcc cacaacagtt aagcactctt     2880

tgactgctga aggaacccca tggatgaggt gcaggctact tcactctttt tttttctttt     2940

ttgagacaga gtctcaccta ttgcccagac tgaagtgcag tggtgcgatc atggatcact     3000

gcagcagcat cctccgagtt caagctatcc ttccacctcc gcctcctgag tagctgggac     3060

cacaggttca cataaccatg cctggctaat ttatttttac ttttatttta aaataaaaga     3120

tgaggtctgt cttatgttgc ccaggctggt ctcaaactat cctacttctt cctcccaaag     3180

tgttgggatt ataggtgtga gccactgcac ccagcctact tcactcttct gaattattct     3240

gatttatttt caacaacttt tgtgaacttg cccgtgatac aaagcagata gtccctgaac     3300

cacagtcgtg cctccttgaa acaagccatt ctactgtgct aatgttttaa tatcacatct     3360

cacaaataac aggggtgaat gtttctctct agcaatctag gcaggtgctg gtgtttcatc     3420

tccatttgaa tgcttgacct cttaatgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgttc     3480

atgggtttta aaagaacagt attttacaaa aggtgtagct tttataagag tgcagaaaag     3540

ggaaggatgt gtttttttct ctcactatag tataagaatc tattttggag aaaaaaagaa     3600

aatatgaggg tctcgaagca tgatttttat ataactagtt tcagttttat ctaataactt     3660

actttttaaa tcaatattta tcaacaatct ttccttgtat gcagtgcttt caaaagatgg     3720

ttttgagtgt ccagtgaaac ttatgacttg gatatatggt tgaagaatca aaacaaaagc     3780

aaaaaaaaaa agcaaaaaaa gaaaagagaa aaaaagaaaa aatgcaaatg gaataatttt     3840

ctattatatt ttagacaaac atatcatttt cgagtatttt aaatactgaa ttcatagttg     3900

ttgtttttta aattccaaca gtaacagctg aatggtttaa tctgactggc ttcctaagaa     3960

atgtttaaga ctcagcttta aaaagaagtt aacattcata tctctgtttt gaaatcaaaa     4020

atcatatttc aaaattcttt cctaggacca tctatgtgtc tcccctcccc tccacaaaaa     4080

ggagaaagag tgcattaaaa tgtttagttg ggttttttaa tttttaattt ttatgttatg     4140

ttttgctttg ttttaagtaa acaaaaattt ttctttcttt actgcatgca tagcacttaa     4200

taaaatggat ttttaaaaaa tccactagta atatcagaat gtccagggag tgactgtcac     4260

tacaatgatg gtttagttta cttctgttcc accttttgat tgaaatattt agttgttagg     4320

ctgaaagcct cggcagttaa gaacttgcct gagttttctt cgttcagcaa cttgacagtt     4380

tgactgatgt gcattatata tagctcaatt atgtctgttt tttatgctaa gtaggaaaac     4440

caaccacaca cattagcaaa ccggcctcaa catataatta gaataaactg tcttcttgtt     4500

ctactcaggg cctttaggtg tgttcattca cggtatggaa atacagtaaa tgaaagattc     4560

caactagttg tcagtgcttc ttgaaattcc aaacagaaag atacattggt caaatccaac     4620

acttggctta tcaatattaa gtcttttacc taaaggccca gccgtcacca gacaacagaa     4680

taatcaatct gcctgaaaat ccctcctcct tgtcctacac tttttgcctg tttgggagaa     4740

tatctttgta ctccattctc ctccctcagc cagttactgg gtcacccatc catgtgttca     4800

tgaatcaatc atcacggcct gcagagcacc tgtcctaagg agggaaaatc ctgtcacact     4860

gcctctcccc attcgtgtgt ggttttcttg atcggtgaga tctgtctctg aagtcactgc     4920

cagcctccct gggaacgtct atagtgcctc ccctgcctta tgtgatggga gttaacaact     4980

cagataagta cacctgagag catttctatc aggtaaactg tcacttaaat ggaggtgtcc     5040

acatcttaat tgtttctcct tgacacattt ctcaatccac gaagccagga gaggtagagt     5100

gaaaatccca gccatggatg aatgtactaa tttgaaagcc aagtgttaag tcggatgttt     5160

tcccgttaca ctactactca gccctctcct gcggccacat caacggatgc aagtcacagt     5220

cttaacacag cctgtgggag acaagcagtt tgtgtgctca cagtatatat tatagtaatt     5280

agggtgactt agagcaaata ctcttcagat cctatgtagt cagtgaaaca aaatggagag     5340

cgtattctga tagaaggacg tcgacggtga atgttctggt ggttgttgcc tgttaagtaa     5400

actttagtgt gtaagttgag tttgtcatta aaatcataaa ccagctgcgg taacagacaa     5460

gcctttggct ggggagtttt aagcctcggt aactgctata aaactagcca tccagttagg     5520

atagaatgtg tttctttctg gttaaaaaaa ggaaaaacca tctaagaaaa tatatatgta     5580

tgtatgtgtg tatacagtgg aattcaaagg accaaagcaa aatttgaaca ggaatctatt     5640

aatttagaat tttataagat atttattaat aaatgttatt tttaaacatt ccatttgaac     5700

agtattctgt aggatctact tgtttttaaa gtgttagtcc ataataaact actatagtta     5760

tgtgtatttt catttttcag ggtttcaaat ggctattctc catcatttgg tggaaatgtt     5820

tgcttagatc tctgtgcata gacatttcaa ggatttttat tgctctgtga gttatttttt     5880

aatcaacatt ctgaacagtt ttttttaaac atttatttct gtgtgttcat ttttaaagta     5940

agctctttca tttaggaagc agagttcagc taaagggaat cagtaactct aactggaaca     6000

gctttcttgt agaagtgtaa aaacagcttc atctctgcct ctctccaccc caccccaatt     6060

tcctagaaag ccttgcacta ttcagctccc ttagtgcttt ttgtcccttc ccgaacaata     6120

tgcagtagct ttaagccatt caagctccat tatgcagtat atctgagaag ggaaaggaaa     6180

caacccattt aaatttgaat aaaaccgtgc ctatgcgaac agtagcaatt tagaatctct     6240

tttctgcttt taaaataatt tatatttaaa aattgcactt tagctttttg atccctttgt     6300

atttctctta ttctctttct aacctcttct ctgtcctcaa acttgccttt gctctccttt     6360

acaatacccc ccacccctcc tccaaggctc tgagcggcat catttaaaat actttacaga     6420

tatttgcacc aggtacattt atgtgcgtcc attggtagca cagctgagac ctgtgtctca     6480

catcagccta ggtgaagcct actacaagaa tgccaaggag aagagccagt acactatatg     6540

gtttatactc tttatccctt tattcatagc atgtttttta aaaatgttat attatgcaac     6600

agatgtgagg cagcagctaa gctatactta agaattttct ctcaccttcc aaaccaaagt     6660

gtcctgaata agccaggaga cttattcttt tgtgcaccct ggtgcacatc tgactgttgt     6720

cctagccata gactctctga ggccactgaa agaacagtgg ccctatcgat ttcattccta     6780

ggtctcaaaa atacaatgtt gccttgtaac ataattaggg acagcacctc tatttcacaa     6840

ttataatcta aggtaggata agacgacaca gcagcaataa acttacaagt aaaattcaat     6900

accaaaacaa acacaaagaa atttaaaaaa caaaaaacct agctcatcat gttgtgaaaa     6960

tgaaaaagtg aatgtccatt caaaatattt tactatttct tgtggagttt ttcagtgatg     7020

taatgcttgt agccaaattg cttaaagagt gtttatatat ttttttcctt ataaattgtc     7080

tattttttaa aaaagctatt taaccacagc tgaagtgggg ggtaaggcca aattgccaac     7140

acttgttaaa agattaatac tcttaagtgg cactctgata cctttccaac ttgtcatcag     7200

aaaggaatca ataattacca actgttgtat ttagaccaac ttacaatatc tagctcatta     7260

gaagccagga tctagaaagc tccttctaag ccatttaaga tattcttaca ttgagcttca     7320

tattatagaa ctttatagga ttggatattt tacaatagaa taatttagcc tcaggactga     7380

gaatgtggaa gctgaataaa ttagctttaa atacatcatt aaaatcttat gcacaataag     7440

ctcattagat tctagttttc tcctttagaa taccaatgcc acagacacta caggagataa     7500

tgaaaggtat cagttgtgtt gagtggaggg agtttaagag aaaggaccct tcccaaccag     7560

cagccagtag aaaatacaac ctactcacct ttttcccttc taagttctgc taaatcacat     7620

ctgcctcata gagaaaggaa tgttgccttt gagaactgtc ttggagaaca gataagcttg     7680

aaatgttctc tctagagagg acatagggtt tgggatcctc tgaaaaggcc cagaaaaata     7740

gctcagttca aatacaatgt tctaggacaa ttggaatata aatattgtcc aaaaatataa     7800

ttaaaagaaa aaagtttagc actgtgtaaa gtaagtgtta actgaggaag tcccaaaaag     7860

gtgctgtcac tttaagttct ggacttgggg ttctttgtat ttgtaaacag caaagcattt     7920

gtgtttgttt gtctatttgt aaagcaacca ccttccttat tggaaggaga aaaaaagggg     7980

tacatacatg taaatacttg ctgcagcatt taatatgttt aattttgtgt taagcttttt     8040

gttgcatcgt gaacacattt attgttacca atggacaatg agttcattaa gactgttcaa     8100

ctaggtcaga tttttacatc tctttctagc aagaagagac aagattttgt gcatttgtac     8160

aaatgttaat atcactgcaa ttccaatata ataaagcact caaatgcaaa taaaaaaaaa     8220

aaaaaaaaaa aaaaa                                                      8235


<210>  2477
<211>  2209
<212>  DNA
<213>  homo sapiens

<400>  2477
gggagggcgg agctggaagg gtgggaagca ccgatccacc ttattgctct ggccgaggcc       60

agagacctcc gggagaggct gggccaccga gccgggcttt actgctccga gggtccgggc      120

gtggggctgg agctggagcc ccgcgcgctg cttttccagc cgcctgcggc cgcgccttca      180

ccgtcggggc gatagcggtg gcaacttggc cgcggctccg cgtggtctcc gggcttcccc      240

gcgccgcctg agccggagct gcccgcttca atcctatttt gtaacggatt atgatccaac      300

cattgaagat tcttacacaa agcagtgtgt gatagatgac agagcagccc ggctagatat      360

tttggataca gcaggacaag aagagtttgg agccatgaga gaacagtata tgaggactgg      420

cgaaggcttc ctgttggtct tttcagtcac agatagaggc agttttgaag aaatctataa      480

gtttcaaaga cagattctca gagtaaagga tcgtgatgag ttcccaatga ttttaattgg      540

taataaagca gatctggatc atcaaagaca ggtaacacag gaagaaggac aacagttagc      600

acggcagctt aaggtaacat acatggaggc atcagcaaag attaggatga atgtagatca      660

agctttccat gaacttgtcc gggttatcag gaaatttcaa gagcaggaat gtcctccttc      720

accagaacca acacggaaag aaaaagacaa gaaaggctgc cattgtgtca ttttctagaa      780

tcccttcagt tttagctacc aacggccagg aaaagccctc atcttctctt tctctcctca      840

gtttacatct tgttggtacc tttctagcct tagacaaatg atcaccatgt tagccttaga      900

cgaagaagct ggctagtcct ttctgtgaag ctaatacaat ggtcatttcc agacaaattt      960

aaaggaaaca ctaaggctgc ttcaaagatt atctgattcc tttaaaatat atgtctatat     1020

acacagacat gctctttttt taagtgctta cattttaata gagatgaatc agttttggaa     1080

tctaagctgt ttgccaagct gaagctacag gttgtgaaat aatttttaac ttttggaatc     1140

atactgccta ctgttactct aaatagaaat atagggtttt ttttaatgtg aatttttgcc     1200

tatctttaaa catttcaatg tcagcctttg ttaaccttaa atacactgaa ttgaatctac     1260

aaaagtgaac catctcagac ctttactgat actacaactt ttgttttctg atggccaaaa     1320

taccaaatgc ctgttgtatt tatggattaa aaactgctta taaaaccctg tgttactact     1380

cctactcttg gagatgataa tattctatgt ggtcaaatat ttggactcat ttaggactta     1440

gatatttcag tgtacttgat tttttaattt aactcttttt cacagccacg ctaagggtaa     1500

aaaggaataa tttccttctg tcttcctttt caagtatttc tgggtaaggg attcaaaaaa     1560

ctaaaactgt ttttgtttgt aatataaaat atggaattga tctttccagg gtcagagatg     1620

attaatgttt ttgctatata cttttataca ttattttctt atcaaactag ttaacaagta     1680

tttttatatg tttgtaagca gatatgcttt catagcatac cttgtgtata tgtaaagata     1740

agtatttaat tctcactgtt cacttttaac tgacaaagaa aaacaagtgg aaactacaga     1800

aactgtggta gaacttttac ttgctggtct ggtcttggtt gtacccatct ttggccagtc     1860

acataactac tcaagaaacc ttcccaatag agtacaacag gatgagactc tgaaatcact     1920

ttcagtattc cctgctagat attgattgtt atttcaagta ttaagtgtaa gcttttaatg     1980

gataattagt ataactgtgg atggcatctg attttgtttt taattctgtg gattgtgttt     2040

aagcaattca atagtatgtt cctgattttg agatgctaag tggtattgca cagttgtcac     2100

tttatcaagt gtgtacaaca gtcccatgaa gtttatagag catacccttg tatagcttca     2160

ggtgctagaa ttaaaattga tctgttatca caagaaaaaa aaaaaaaaa                 2209


<210>  2478
<211>  4322
<212>  DNA
<213>  homo sapiens

<400>  2478
gcgcatgcgc gaactcctgg cgggacctac gcggtagaag tttctactaa gtgaaaagga       60

agagcgaggg attcttttct ctgtggtcta cagcagcagc actattatta aaaatatttg      120

gaaagacaac ctggcaagtt ttgaaaaaga tttttttaaa aacggtaggg ttccgctcac      180

agtgggaggc ggggctcagt ggtccagaaa cgcctcttca gaagagggcg ggctcgccga      240

gaggcggggt ctcgggccca ctcggatgac gtgccgcgta gaagtatcgc gggaagagga      300

agggagcgta actcttagaa gtcactatgg tgacggggag gtaccaggta tttgagagca      360

atcgccaccg ctttcctgga acttgagtaa atacaatcaa gtggcatctt aaatttttgc      420

tggaagtgga gtcatgagac taaagatatc tcttttaaaa gaaccaaagc atcaagaatt      480

agtaagctgt gtgggctgga ctactgctga agagctgtat tcatgtagtg atgatcacca      540

gatagtgaag tggaacttgt taaccagtga aacaactcaa atagtaaagc ttcctgatga      600

tatttaccct attgattttc actggtttcc aaaaagtttg ggtgtaaaga aacaaaccca      660

ggcagaaagc tttgtcctca caagttctga tggtaaattt catctgattt ccaagttagg      720

aagagtggaa aaaagtgtag aagctcactg tggagcagta cttgcaggaa gatggaatta      780

tgaaggaaca gcattagtta cagttggaga agatggacaa ataaaaattt ggtcaaagac      840

tgggatgctt agatcaactt tagctcagca aggaacacca gtgtattcag tagcgtgggg      900

ccctgattca gaaaaggttc tttatacagc aggcaagcag ctaatcatta aacctcttca      960

accaaatgct aaagttttgc agtggaaagc tcatgatggc attattttaa aagtagattg     1020

gaactcggtc aatgatctta ttttatctgc tggtgaagac tgtaaatata aggtatggga     1080

tagttacggc cgcccactgt acaattcaca acctcatgag catcccatta cttcagttgc     1140

ctgggctcca gatggagaat tatttgctgt tggatcgttt catactttac gcttgtgtga     1200

taaaactggg tggtcatatg cattagaaaa acccaacact ggcagcatat ttaatattgc     1260

atggtctatc gatggcactc agattgctgg agcctgtgga aatggacatg tcgtttttgc     1320

acatgtggtg gaacaacatt gggagtggaa aaattttcaa gtaacattaa cgaaaagaag     1380

agccatgcag gttcgtaatg ttcttaatga tgcagtggat ttactggaat tccgtgatag     1440

agtcattaaa gcatctttga actatgcaca cttagttgtt tcaacgtctc ttcaatgtta     1500

cgtgttctcc acgaagaact ggaacacacc aattatattt gatctcaaag aaggaactgt     1560

tagtttgatt ctgcaggcag aaagacattt tcttcttgta gatggtagta gtatctattt     1620

atattcatat gaagggcgct ttatttcatc tccaaaattt cctggaatga gaacagatat     1680

tctgaatgca cagactgtgt ctttgagtaa tgataccata gcaataagag acaaagctga     1740

tgaaaaaata atcttcctct ttgaggcatc aaccggaaag ccgttaggtg atggaaagtt     1800

tctttctcat aagaatgaaa tcttggaaat tgctctggat caaaaaggac ttaccaatga     1860

tagaaaaatt gctttcattg ataaaaatag agatctctgt atcacttctg tgaaacgatt     1920

tgggaaggaa gaacaaatta tcaagcttgg aacaatggtg catactttgg catggaacga     1980

tacatgcaat atcctttgtg gacttcaaga tactcgattt atagtgtggt attaccccaa     2040

tacagtttat gtggacagag acattttgcc taaaacatta tatgaaaggg atgcaagtga     2100

atttagtaaa aatccccata ttgtgagttt tgttggaaat caagtaacta ttagaagagc     2160

tgatggctcc ctggttcaca tcagcataac accatatcct gctattctcc atgaatatgt     2220

aagcagttca aaatgggaag atgctgtgag actttgtcgc tttgttaagg agcaaaccat     2280

gtgggcttgt ctagctgcta tggcagttgc taatcgagat atgactactg cagaaatagc     2340

ctatgcagca attggtgaaa ttgataaggt tcagtacatc aattctataa aaaatcttcc     2400

atctaaagaa tcaaaaatgg cccacatact actgtttagt gggaacatac aggaggctga     2460

aatagtactt cttcaggctg gccttgttta tcaagcaatc cagatcaata ttaatctcta     2520

caactgggaa agggcactgg aattggctgt aaaatacaaa acacatgttg atacagttct     2580

tgcttaccgt caaaagtttt tggagacatt tggtaaacag gaaactaata aacgatactt     2640

gcattatgca gaaggtctcc aaatagattg ggagaaaatc aaagccaaaa ttgagatgga     2700

aattacaaaa gaaagagagc aatcatcaag cagccaatcc agcaagagta taggtttaaa     2760

gccctaaatg ccatgcgtat ctttaagaaa ttttatcttt tgaaacacgt tctgattaac     2820

caagggtaag catgttttgg ttgctaaaga aaaaagcata atctttaacc gagtataagt     2880

acttgctgtg tatttagtgt aaaagtacat gcagaaagat gaaacacaaa gtaattgatg     2940

tatttctatc ttttatattt tttagtccaa taattagcaa aatattacta tgtacttaag     3000

agatacctgt gtagtgtcga ttatatgtca gttttttgcc cattacttca tccctaaatc     3060

ttcagcatga acaaatatta atgtcgataa taaaacattg gactctttga aatgtatgtt     3120

accattaatt tctatttgac ctctaaattg taaaatgcct ccaaaagttt atttatagaa     3180

caaaaataca tgaggatgga tttgtacaaa tgtataaaat gccactattt atacaccaag     3240

ttcatagcag cattactgga atagcaaaag atggaaacag ctcaagtgtc tatcatgaat     3300

ggataaacaa atgtgctata atacatacaa tggaatatta tttagcttta aaaaggaatg     3360

aaattctgat aaatactacc tcaggataaa ccttgaaaac actatgctaa gtgaaataag     3420

ccagacacaa aaggccaaat atgatgccac ttttatgagg taccagcata ggcaagttca     3480

cagaaacaga aaggagaata gtggttgcca gggactgcag ggaggaggaa atggggggtg     3540

gggttattgt ttaacgagta catagtttct gtttgggatg aacaaattct ggaaatggat     3600

agcgatgatg gttgctcaac attttgaatg ttaatgccac taaattgtac ccataaaaat     3660

ggttaaaatg gtaaattttg ttatgtatat tttatcataa tttaaaaaat atatctagaa     3720

tgggcaagaa ggattctcct cattcctctc ttgacttgag aatgatcagt caataggccc     3780

tgaagtctga atttgtgaaa atttccttgg gtgacaaact tgtttgatta ctctatttag     3840

tgtatcccaa agttattacc acataatctt ttaaacaata aaacaaatac cccttagaaa     3900

gtcttctgca aacccatttc tgaaaatggt acattatagg gtgggtatag atgcatagat     3960

atgggattat gtatgatata tatatatata cacacacaca caaagggata gagagattac     4020

ctctcttaac ccccatttta attactatgt ctaggttttt taaataaaaa tcttttcttt     4080

ttaacatgtt tcttttcttt tccggaatat tggaatattc tgttcttgat ccagatgaaa     4140

tctgattgag cagtgtactt acaagttgta ctgtgtatgt gtttcctata ttgttatatt     4200

tcaataagaa gcttaaaatg tttaaaaata aatggttaaa aggttttatg ttatgtatat     4260

tttaccacaa taaatgcaaa aaataaaaag tctgtgttct aaacaaaaaa aaaaaaaaaa     4320

aa                                                                    4322


<210>  2479
<211>  3160
<212>  DNA
<213>  homo sapiens

<400>  2479
gtaactctac ggcctagcaa ccgttgccaa ggagctcgac tctgggagcg gtctagagcc       60

cgggcgcctc ctggggggtg gggaaacggt ttcgtgagga gaatttgagg taacctcgcc      120

aactcgcggt cggaagctcc tctgaacccc gaaataggag agagctcccg tcctctctcg      180

gtcctgatgc agcacctcgc aagtggaagg ggtcgtcgcg gttaagcccc cggatagggg      240

aatcgggccc cttctgggat tcgagcggat ccaggccgct ccctggaggg atgaactgtc      300

gaggggccca gggcagcccc cgctagaggc ccggtcgggt gtggggtccc ctgtcccctg      360

tcccgagccc ggggaggggg acactatttc tggtactccc aggaggctgc gggtcgatgc      420

tcgtgccagc ctgggaccca ggcagcacgg tttctctccc aaattgtgcc agagaacacg      480

cacgtcctgg ttttcattgt tccccgcctc ctgcgactcg tttgtggtta aaattataag      540

acctaattat gagtgatcaa attaaattca ttatggacag tctcaataag gagcccttta      600

ggaagaacta taatttaatc acgtttgatt ccttggagcc aatgcaacta ttacaagttc      660

tcagtgatgt tctggctgag attgacccaa agcaacttgt ggatatcaga gaggagatgc      720

cagagcagac agccaaacga atgttgagcc ttcttggtat tcttaagtac aaaccttcag      780

gaaatgccac agatatgagt acttttcgtc agggtttggt gattggaagt aaacctgtaa      840

tttacccagt gctccactgg cttcttcaga ggactaatga actgaagaaa agagcatatt      900

tagctcgttt tttaataaaa cttgaggtac caagtgagtt tcttcaggat gaaactgtgg      960

ctgacaccaa taaacagtat gaagagttaa tggaagcctt taaaactttg cataaagaat     1020

atgagcagct caagatatct ggattttcta cagcagaaat aagaaaggat atcagtgcaa     1080

tggaagaaga aaaggatcag ctcattaaga gagttgaaca tttgaagaaa agggttgaga     1140

cagctcagaa tcatcaatgg atgcttaaaa tagcaaggca acttcgagtt gaaaaagaga     1200

gagaagaata tcttgcacaa cagaaacagg aacaaaagaa tcagctattt catgcagtgc     1260

aaagattgca aagagtacaa aaccagctga aaagcatgcg ccaagctgca gcagatgcaa     1320

agcctgaaag tttaatgaag aggctagagg aggagataaa atttaattta tatatggtaa     1380

ctgaaaaatt tcctaaagaa ttagaaaata agaaaaagga attacatttt ttacaaaaag     1440

tagtttcaga gccagctatg ggccattctg atcttcttga acttgaatct aaaataaatg     1500

aaataaacac agaaattaac cagttgattg aaaagaaaat gatgagaaat gagcccattg     1560

aaggcaaact ctcactgtat aggcaacagg catctatcat ttcccgtaaa aaagaagcca     1620

aagctgagga acttcaggag gccaaggaga agttagccag cctagagaga gaagcatcag     1680

taaagagaaa tcagacccgt gaatttgatg gtactgaagt tttaaaggga gatgagttca     1740

aacgatatgt caataaactt cgaagcaaga gtacagtttt caaaaagaag catcagataa     1800

tagctgaact taaagctgaa ttcggtcttt tgcagaggac tgaagaactt cttaagcaac     1860

gtcatgaaaa tattcaacaa caactgcaaa ctatggagga gaaaaagggt atatctggat     1920

atagttacac ccaagaagag ctagaaagag tatctgcact gaagagtgaa gttgatgaaa     1980

tgaaaggacg aacattggat gatatgtctg aaatggtgaa aaaactgtat tcattggtat     2040

ctgaaaagaa gtcagctctt gcctcagtta taaaagagct acgacagttg cgtcaaaaat     2100

atcaagaact gacccaggag tgtgatgaaa agaaatccca gtatgatagc tgtgcagcag     2160

gcctcgaaag caatcggtcc aaattagaac aggaagttag aagactccgt gaagaatgtc     2220

ttcaagaaga aagtagatac cattatacaa attgtatgat taagaaccta gaagttcaac     2280

ttcgtcgtgc tactgatgag atgaaggcat atatctcttc tgatcaacaa gaaaaaagaa     2340

aggcaattag ggaacagtat accaaaaata ctgctgaaca agaaaacctt ggaaagaaac     2400

ttcgggaaaa acaaaaagtt atacgagaaa gtcatggtcc aaatatgaaa caagcaaaaa     2460

tgtggcgtga tttggaacaa ttaatggaat gtaagaaaca gtgctttctg aaacaacaaa     2520

gccaaacttc cattggtcag gtaattcagg agggtgggga ggaccggcta atactgtgaa     2580

ttcttgtgtc atcgtttggg gttttacttg ataccactag ctataagcct aatctcataa     2640

tgtatttctt ttttgaaact gatttgtata gcattttgtt ttcagaagag ccattcttta     2700

ttaagttttc atagaaaata atgttaaggt agatttagtt tgaatgtttt ttcatatgaa     2760

aaagaggctt ttattctttt ccatagttta gacatcactg gcgtcttctg agttttatga     2820

gacaggaaac taagtttact atctgtaaat gtaaacatat gtccattaag aaacatgtag     2880

ttttttttta gaatgtaata acccagtggc ttactgtttt tcttaatctc ttttaaaaaa     2940

actttagaag aatcttttag gaactaatat ctcttgttct gaagaaacat ttatctgacg     3000

ttcagcagtt cctacagttt tacttcagtt tatttttctt ctgtaaaatg caagaaaatt     3060

taatattttg actaacatgt cttttctgtt tgtatcattt aaaggcaaat aaacttggta     3120

cgtatttcat atctatttaa aaaatgtaaa aaaaaaaaaa                           3160


<210>  2480
<211>  3555
<212>  DNA
<213>  homo sapiens

<400>  2480
tttcagccaa ccagactgga gcagctgcga gtgctacatc ttggctgtct gaagcgattg       60

gctcctctct ggggagtgga gggtgttcag ttattaatga ccgctgagca ggcagcacca      120

tgtcagtgtg acaactgatc gggtgaacga tgcaccacta accaccatgg aaacaaggaa      180

aaataaagcc agctcacagg atctctcttc actggattga gagcctcagc ctgccgactg      240

agaaaaagag ttccaggaaa aagaaggaat cccggctgca gcctcctgcc ttcctttata      300

ttttaaaata gagagataag attgcgtgca tgtgtgcata tctatagtat atattttgta      360

cactttgtta cacagacaca caaatgcacc tatttatacc gggcaagaac acaaccatgt      420

gattatctca accaaggaac tgaggaatcc agcacgcaag gacatcggag gtgggctagc      480

actgaaactg cttttcaagc atcatgctgc tattcctgca aatactgaag aagcatggga      540

tttaaatatt ttacttctaa ataaatgaat tactcaatct cctatgacca tctatacata      600

ctccaccttc aaaaagtaca tcaatattat atcattaagg aaatagtaac cttctcttct      660

ccaatatgca tgacattttt ggacaatgca attgtggcac tggcacttat ttcagtgaag      720

aaaaactttg tggttctatg gcattcatca tttgacaaat gcaagcatct tccttatcaa      780

tcagctccta ttgaacttac tagcactgac tgtggaatcc ttaagggccc attacatttc      840

tgaagaagaa agctaagatg aaggacatgc cactccgaat tcatgtgcta cttggcctag      900

ctatcactac actagtacaa gctgtagata aaaaagtgga ttgtccacgg ttatgtacgt      960

gtgaaatcag gccttggttt acacccagat ccatttatat ggaagcatct acagtggatt     1020

gtaatgattt aggtctttta actttcccag ccagattgcc agctaacaca cagattcttc     1080

tcctacagac taacaatatt gcaaaaattg aatactccac agactttcca gtaaacctta     1140

ctggcctgga tttatctcaa aacaatttat cttcagtcac caatattaat gtaaaaaaga     1200

tgcctcagct cctttctgtg tacctagagg aaaacaaact tactgaactg cctgaaaaat     1260

gtctgtccga actgagcaac ttacaagaac tctatattaa tcacaacttg ctttctacaa     1320

tttcacctgg agcctttatt ggcctacata atcttcttcg acttcatctc aattcaaata     1380

gattgcagat gatcaacagt aagtggtttg atgctcttcc aaatctagag attctgatga     1440

ttggggaaaa tccaattatc agaatcaaag acatgaactt taagcctctt atcaatcttc     1500

gcagcctggt tatagctggt ataaacctca cagaaatacc agataacgcc ttggttggac     1560

tggaaaactt agaaagcatc tctttttacg ataacaggct tattaaagta ccccatgttg     1620

ctcttcaaaa agttgtaaat ctcaaatttt tggatctaaa taaaaatcct attaatagaa     1680

tacgaagggg tgattttagc aatatgctac acttaaaaga gttggggata aataatatgc     1740

ctgagctgat ttccatcgat agtcttgctg tggataacct gccagattta agaaaaatag     1800

aagctactaa caaccctaga ttgtcttaca ttcaccccaa tgcatttttc agactcccca     1860

agctggaatc actcatgctg aacagcaatg ctctcagtgc cctgtaccat ggtaccattg     1920

agtctctgcc aaacctcaag gaaatcagca tacacagtaa ccccatcagg tgtgactgtg     1980

tcatccgttg gatgaacatg aacaaaacca acattcgatt catggagcca gattcactgt     2040

tttgcgtgga cccacctgaa ttccaaggtc agaatgttcg gcaagtgcat ttcagggaca     2100

tgatggaaat ttgtctccct cttatagctc ctgagagctt tccttctaat ctaaatgtag     2160

aagctgggag ctatgtttcc tttcactgta gagctactgc agaaccacag cctgaaatct     2220

actggataac accttctggt caaaaactct tgcctaatac cctgacagac aagttctatg     2280

tccattctga gggaacacta gatataaatg gcgtaactcc caaagaaggg ggtttatata     2340

cttgtatagc aactaaccta gttggcgctg acttgaagtc tgttatgatc aaagtggatg     2400

gatcttttcc acaagataac aatggctctt tgaatattaa aataagagat attcaggcca     2460

attcagtttt ggtgtcctgg aaagcaagtt ctaaaattct caaatctagt gttaaatgga     2520

cagcctttgt caagactgaa aattctcatg ctgcgcaaag tgctcgaata ccatctgatg     2580

tcaaggtata taatcttact catctgaatc catcaactga gtataaaatt tgtattgata     2640

ttcccaccat ctatcagaaa aacagaaaaa aatgtgtaaa tgtcaccacc aaaggtttgc     2700

accctgatca aaaagagtat gaaaagaata ataccacaac acttatggcc tgtcttggag     2760

gccttctggg gattattggt gtgatatgtc ttatcagctg cctctctcca gaaatgaact     2820

gtgatggtgg acacagctat gtgaggaatt acttacagaa accaaccttt gcattaggtg     2880

agctttatcc tcctctgata aatctctggg aagcaggaaa agaaaaaagt acatcactga     2940

aagtaaaagc aactgttata ggtttaccaa caaatatgtc ctaaaaacca ccaaggaaac     3000

ctactccaaa aatgaacaaa aaaaaaaaaa gcgaaagact gcagttgtgc taaaaacaaa     3060

acaaaacaaa caaacaaaca aaaaagtaaa aaaagattac tttcgagaga gaagtttaag     3120

cttcaccaat gctgctcctg accaatggaa atatgtacaa cttcagcatt ttaagtaact     3180

ggcttcaagg ggtactgtgg caaccaaata aaataactcc attttctaaa actttcatgt     3240

aacttttatg tctggactac agttcaagtg gacaaaaaca tttctgtatt ttttttaagt     3300

aaataagagt agttgaactg agcaatacct cctcctgtgt tgtattacac atattagcca     3360

cgagtttttg cagtgaccag ataaacttga attgacacgt ggtgtaataa aatggacaaa     3420

ttctgtagag tagacacagt gagtatgtgg acctctttta taaggaaaaa tacattttgg     3480

attaaaatca attgcttctg tcttgttttg tttctaaata aagaataatt tctgggaaaa     3540

aaaaaaaaaa aaaaa                                                      3555


<210>  2481
<211>  3637
<212>  DNA
<213>  homo sapiens

<400>  2481
tttcagccaa ccagactgga gcagctgcga gtgctacatc ttggctgtct gaagcgattg       60

gctcctctct ggggagtgga gggtgttcag ttattaatga ccgctgagca ggcagcacca      120

tgtcagtgtg acaactgatc gggtgaacga tgcaccacta accaccatgg aaacaaggaa      180

aaataaagcc agctcacagg atctctcttc actggattga gagcctcagc ctgccgactg      240

agaaaaagag ttccaggaaa aagaaggaat cccggctgca gcctcctgcc ttcctttata      300

ttttaaaata gagagataag attgcgtgca tgtgtgcata tctatagtat atattttgta      360

cactttgtta cacagacaca caaatgcacc tatttatacc gggcaagaac acaaccatgt      420

gattatctca accaaggaac tgaggaatcc agcacgcaag gacatcggag gtgggctagc      480

actgaaactg cttttcaaga cgaggaagag gaggagaaag agaaagaaga ggaagatgtt      540

gggcaacatt tatttaacat gctccacagc ccggaccctg gcatcatgct gctattcctg      600

caaatactga agaagcatgg gatttaaata ttttacttct aaataaatga attactcaat      660

ctcctatgac catctataca tactccacct tcaaaaagta catcaatatt atatcattaa      720

ggaaatagta accttctctt ctccaatatg catgacattt ttggacaatg caattgtggc      780

actggcactt atttcagtga agaaaaactt tgtggttcta tggcattcat catttgacaa      840

atgcaagcat cttccttatc aatcagctcc tattgaactt actagcactg actgtggaat      900

ccttaagggc ccattacatt tctgaagaag aaagctaaga tgaaggacat gccactccga      960

attcatgtgc tacttggcct agctatcact acactagtac aagctgtaga taaaaaagtg     1020

gattgtccac ggttatgtac gtgtgaaatc aggccttggt ttacacccag atccatttat     1080

atggaagcat ctacagtgga ttgtaatgat ttaggtcttt taactttccc agccagattg     1140

ccagctaaca cacagattct tctcctacag actaacaata ttgcaaaaat tgaatactcc     1200

acagactttc cagtaaacct tactggcctg gatttatctc aaaacaattt atcttcagtc     1260

accaatatta atgtaaaaaa gatgcctcag ctcctttctg tgtacctaga ggaaaacaaa     1320

cttactgaac tgcctgaaaa atgtctgtcc gaactgagca acttacaaga actctatatt     1380

aatcacaact tgctttctac aatttcacct ggagccttta ttggcctaca taatcttctt     1440

cgacttcatc tcaattcaaa tagattgcag atgatcaaca gtaagtggtt tgatgctctt     1500

ccaaatctag agattctgat gattggggaa aatccaatta tcagaatcaa agacatgaac     1560

tttaagcctc ttatcaatct tcgcagcctg gttatagctg gtataaacct cacagaaata     1620

ccagataacg ccttggttgg actggaaaac ttagaaagca tctcttttta cgataacagg     1680

cttattaaag taccccatgt tgctcttcaa aaagttgtaa atctcaaatt tttggatcta     1740

aataaaaatc ctattaatag aatacgaagg ggtgatttta gcaatatgct acacttaaaa     1800

gagttgggga taaataatat gcctgagctg atttccatcg atagtcttgc tgtggataac     1860

ctgccagatt taagaaaaat agaagctact aacaacccta gattgtctta cattcacccc     1920

aatgcatttt tcagactccc caagctggaa tcactcatgc tgaacagcaa tgctctcagt     1980

gccctgtacc atggtaccat tgagtctctg ccaaacctca aggaaatcag catacacagt     2040

aaccccatca ggtgtgactg tgtcatccgt tggatgaaca tgaacaaaac caacattcga     2100

ttcatggagc cagattcact gttttgcgtg gacccacctg aattccaagg tcagaatgtt     2160

cggcaagtgc atttcaggga catgatggaa atttgtctcc ctcttatagc tcctgagagc     2220

tttccttcta atctaaatgt agaagctggg agctatgttt cctttcactg tagagctact     2280

gcagaaccac agcctgaaat ctactggata acaccttctg gtcaaaaact cttgcctaat     2340

accctgacag acaagttcta tgtccattct gagggaacac tagatataaa tggcgtaact     2400

cccaaagaag ggggtttata tacttgtata gcaactaacc tagttggcgc tgacttgaag     2460

tctgttatga tcaaagtgga tggatctttt ccacaagata acaatggctc tttgaatatt     2520

aaaataagag atattcaggc caattcagtt ttggtgtcct ggaaagcaag ttctaaaatt     2580

ctcaaatcta gtgttaaatg gacagccttt gtcaagactg aaaattctca tgctgcgcaa     2640

agtgctcgaa taccatctga tgtcaaggta tataatctta ctcatctgaa tccatcaact     2700

gagtataaaa tttgtattga tattcccacc atctatcaga aaaacagaaa aaaatgtgta     2760

aatgtcacca ccaaaggttt gcaccctgat caaaaagagt atgaaaagaa taataccaca     2820

acacttatgg cctgtcttgg aggccttctg gggattattg gtgtgatatg tcttatcagc     2880

tgcctctctc cagaaatgaa ctgtgatggt ggacacagct atgtgaggaa ttacttacag     2940

aaaccaacct ttgcattagg tgagctttat cctcctctga taaatctctg ggaagcagga     3000

aaagaaaaaa gtacatcact gaaagtaaaa gcaactgtta taggtttacc aacaaatatg     3060

tcctaaaaac caccaaggaa acctactcca aaaatgaaca aaaaaaaaaa aagcgaaaga     3120

ctgcagttgt gctaaaaaca aaacaaaaca aacaaacaaa caaaaaagta aaaaaagatt     3180

actttcgaga gagaagttta agcttcacca atgctgctcc tgaccaatgg aaatatgtac     3240

aacttcagca ttttaagtaa ctggcttcaa ggggtactgt ggcaaccaaa taaaataact     3300

ccattttcta aaactttcat gtaactttta tgtctggact acagttcaag tggacaaaaa     3360

catttctgta ttttttttaa gtaaataaga gtagttgaac tgagcaatac ctcctcctgt     3420

gttgtattac acatattagc cacgagtttt tgcagtgacc agataaactt gaattgacac     3480

gtggtgtaat aaaatggaca aattctgtag agtagacaca gtgagtatgt ggacctcttt     3540

tataaggaaa aatacatttt ggattaaaat caattgcttc tgtcttgttt tgtttctaaa     3600

taaagaataa tttctgggaa aaaaaaaaaa aaaaaaa                              3637


<210>  2482
<211>  1657
<212>  DNA
<213>  homo sapiens

<400>  2482
cttttgaagt taacaaaaat tgagtccctg gctgggaggt cccccgagtg ttccgctgtg       60

ggctggaggt ggcgtttctg tcgtgattta tgtggagtgg ttcaaaacag aagttaatca      120

ctcgggaagc ggacgggagg ggcggcgcta ctgcgcatgc ccgggagccg cctggagttt      180

ggaactccac attctttcag acccggcccg ctgcggggcg ttcctggggg gtagcctcaa      240

ggccagcggg gttccttcgg ctgcgtttct gtgggaggcc ctgaaacgcg cggagcttcc      300

ctctgcctcc aggctttccc agcgagagtg aaattaaact tgaaactcgg atcaactggc      360

agtcgttgtt ggtattgttg cagcatctgg cagtgagact gaggatgagg acagcatgga      420

cattcccttg gacctttctt catccgctgg ctcaggcaag agaaggagaa ggggcaacct      480

acccaaggag tctgtgcaga ttcttcggga ttggctgtat gagcaccgtt acaatgccta      540

tccttcagag caagaaaaag cgttgctgtc ccagcaaaca cacctgtcta cgctacaggt      600

ctgtaactgg ttcatcaacg cccgccgcag gctcctccct gacatgctga gaaaggatgg      660

caaagatcca aatcagttca caatttcccg ccgtggggcc aagatttctg aaacgagctc      720

tgtggagtcc gtgatgggca tcaaaaactt catgccagct ctagaggaga ccccatttca      780

ttcctgtaca gctgggccaa acccaaccct agggaggcca ctgtctccta agccgtcatc      840

cccgggatca gttttggctc gtccatcagt gatctgccat accactgtga ctgcattgaa      900

agatgtccct ttctctctct gccagtcggt cggtgtggga caaaacacag atatacagca      960

gatagcggcc aaaaacttca cagacacctc tctcatgtac ccagaggaca cttgtaaatc     1020

tggaccaagt acgaatacac agagtggtct tttcaacact cctcccccta ctccaccgga     1080

cctcaaccag gacttcagtg gatttcagct tctagtggat gttgcactca aacgggctgc     1140

agagatggag cttcaggcaa aacttacagc ttaacccatt ttcaagcaaa acagttctca     1200

gaaatgtcat gattgccggg gtgaaggcaa gagatgaatt gcattatttt atatattttt     1260

tattaatatt tgcacatggg attgctaaaa cagcttcctg ttactgagat gtcttcaatg     1320

gaatacagtc attccaagaa ctataaactt aaagctactg tagaaacaaa gggttttctt     1380

ttttaaatgt ttcttggtag attattcata atgtgagatg gttcccaata tcatgtgatt     1440

ttttttttcc tccccttccc tttttttgtt attttttcag actgtgcaat acttagagaa     1500

cctatagcat cttctcattc ccatgtggaa caggatgccc acatactgtc taattaataa     1560

attttccatt ttttttcaaa caagtatgaa tctagttggt tgatgccttt tttttcatga     1620

cataataaag tattttcttt aaaaaaaaaa aaaaaaa                              1657


<210>  2483
<211>  3786
<212>  DNA
<213>  homo sapiens

<400>  2483
agcttctgta agagacggag aggcgcagag tgagggcggg tccgcgcgtc ctcagagccc       60

gctggaggct cggagctgct acccgcagac ttctcccgca cagggctcgc aaagagcgtg      120

attccgagag cctgagactg acgcccgacc tggaaaccag agaagacttc cttagccttt      180

cggatcgcac ttgaggctgg aggcatgagt cctgtgaggc gttggggcag cccctgcctt      240

ttccccttgc agctcttcag cctctgctgg gtgctctcag tggcccagag caaaacagtc      300

cgatacagca ccttcgagga ggatgccccc ggcacggtca tcgggaccct ggccgaggac      360

ctgcatatga aagtatcggg tgacacaagc ttccgcctga tgaagcaatt caacagctct      420

ctgctccggg tgcgcgaagg cgacgggcag ctgaccgtcg gggacgccgg cctggaccgc      480

gagcggctgt gtggccaggc cccgcagtgc gtgctggcct tcgatgtggt cagcttctcg      540

caggagcagt tccggctggt gcacgtggag gtagaggtga gggacgtcaa cgaccacgcg      600

ccgcgcttcc ccagggccca gatcccggta gaggtgtccg agggtgcggc agtgggcacg      660

cgcatcccct tggaggtgcc ggtggacgag gacgtgggcg ccaacgggct gcagaccgtg      720

cgcctggccg agccgcacag cccctttcgc gtggagctgc agacgcgagc ggacggcgct      780

cagtgcgcag acctggtgct gctgcaggag ctggaccgcg agagccaggc cgcctacagc      840

ctggagctgg tggcccagga cggcggccgc ccgccgcgct ccgccacggc tgccctcagc      900

gtgcgcgtcc tggatgcgaa tgaccacagc ccggccttcc cgcagggcgc cgtggccgaa      960

gtggagctgg cggaagacgc gcccgtgggc tccctgcttc tcgacctgga cgcagccgac     1020

cccgacgagg gacctaacgg cgacgtggtg ttcgcatttg gcgcccgcac cccgccggag     1080

gcgcgccgcc tctttcggct tgacccgcga tcaggccgcc tcaccctggc cgggcccgtg     1140

gactacgagc gtcaggacac ctacgagctg gacgtgcggg cgcaggaccg cggacccggg     1200

ccccgcgctg ccacctgcaa ggtcatcgtg cgcatccgag acgtcaatga caacgcaccc     1260

gacatcgcca tcaccccgct ggccgcccca ggcgcgccgg caacctcacc cttcgccgct     1320

gccgccgccg ccgctgcact cgggggagcg gacgctagct cgccggcggg agccgggacg     1380

ccggaggctg gtgccacttc gctggtgccg gagggggcgg cgcgcgagag cctggtggcc     1440

ctggtcagca cctcggacag ggactcgggc gccaacgggc aagtgcgctg cgccctctat     1500

gggcacgagc acttccggct gcagccggcc tacgcgggca gctacctggt ggtgaccgcg     1560

gcgtcgctgg accgcgaacg catcgccgag tacaacttga cgctggtggc cgaggatcgc     1620

ggcgcgcccc cgctgcgcac agtgcggccc tacacggtgc gtgtgggcga cgagaacgac     1680

aacgcgccgc tcttcacgcg gccggtctat gaggtgtcgg tgcgcgagaa caacccgcca     1740

ggcgcctacc tggccacggt ggccgcccgc gaccgggacc tgggccgcaa cggccaggtc     1800

acctaccggc tgctggaggc cgaggtgggc cgcgccgggg gcgccgtgtc cacttatgtc     1860

tcggtggacc cagctaccgg agccatctac gcgctgcgca gcttcgacta tgagacgctg     1920

cgccaactcg acgttcgcat ccaagctagc gacggcggct cccctcagct ttccagcagc     1980

gccctagtgc aagtgcgcgt gctggaccag aacgaccatg cgccagtcct ggtgcacccg     2040

gcgccagcca atggctccct agaagtggcg gtgcctgggc gcaccgcaaa ggacacggtt     2100

gtggcccgtg tgcaggcccg ggatgcagac gagggagcca acggggagct ggcgttcgag     2160

ctgcagcagc aggagccgcg cgaagccttc gccatcggcc gccgcacggg ggagatactg     2220

ctcaccggcg acctctcgca ggagccaccc ggtcgcgtgt tcagggcgct cctggtcata     2280

tccgacggcg gccgtccccc gctcaccacc accgcaactg tcagcttcgt ggtaacagca     2340

gggggcgggc gtgggccggc tgcgcctgcc agtgcaggaa gcccggagcg ttcccgcccg     2400

cctggctctc ggctcggggt gtccgggtcg gtgctgcaat gggacacgcc gctgatcgtc     2460

atcatcgtgc tggccgggag ctgcacgctg ctgctggccg ccatcatcgc catcgccacc     2520

acctgcaacc gccgcaagaa ggagccctac ggtgcctccc cgggttttgg aaaggagccg     2580

gcgccccctg tggcggtgtg gaaaggacac tccttcaaca ccatttctgg cagagaagca     2640

gagaagttca gcggcaaaga cagcggtaaa ggggacagtg atttcaacga cagcgattcc     2700

gacatcagcg gggacgctct gaaaaaggat ctcatcaacc acatgcagag tggactgtgg     2760

gcgtgcaccg ctgagtgtaa gatcctgggc cactctgacc gctgctggag cccatcctgc     2820

agcgggccca acgcacatcc atcgcctcac ccaccagccc agatgtcaac cttctgtaag     2880

agcacgtcac tgcctcggga tcctctgcgc agggacaatt actaccaggc ccagctgccc     2940

aagacagtgg ggctgcagag cgtctatgag aaagtactgc acagagacta tgacaggaca     3000

gtcactctgc tctcccctcc ccgtccaggg aggctcccag acctgcagga gattggagta     3060

cccctctacc agtcccctcc tggcaggtac ctgtccccga agaagggagc caatgaaaat     3120

gtgtaatccc atgctgcatg tcttcacaca tatacaggtc actccgagaa gcccctaagt     3180

tattgaccgg tttcagtgtt gtatatataa atatgcaaga tgtgccttac aatgaagttg     3240

ttggaagcta tttccaatca cattggtact gtttggtatt tgcaaacaaa aatgtagtta     3300

atgtaatttt tatgaaatgt gtgcagtatt taatttttct tatgctattg actttgattt     3360

caattgcggc ttgccatttt cttagtgttt ttaacctgta cattgtgtaa tgtaatgttt     3420

gtatataatg aaattttgtt atatttttat ataataaaag ctaaagtgga agttattgcc     3480

aaaggaactg tctgtaagac aaaaaacaaa acatgttgga attacttaat tgaaatttat     3540

ctttcacctg aaacaaccta gtgtttgaga aattttgcct tgccaagtat aacttgtata     3600

tcttgactct gtggtagatt tcaagttcaa tgttatttaa ttacatttgg ttttccgtaa     3660

accgtgtcac ttataagcac agtaataaaa gatttgtcat gtgtttgaag aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaa                                                                3786


<210>  2484
<211>  6404
<212>  DNA
<213>  homo sapiens

<400>  2484
gactaatggc cctaactaag tattaacccc tgccaagaaa agagctactt cctcttgaag       60

taaatgaaga tagtgatgct ttctcttaaa ctttacttat aaaaagcatc aaagggggga      120

atgaagcagg aaatataaaa ggaaaaacaa gtaaagggaa aacaagtcct ttcctgacca      180

gtctgactca ctccaaagtc ctgctggagc tatgataatt atctgcaagg ccaggcaggg      240

gctccgaagg agtgggctcc aggagcaggg atgagaaaaa caagttctcc ttatcagttt      300

ccctgtttga aattctctcc ccataacatt attctttgtt ctgctctcac aactattttt      360

gtaactattt ctgcaagtct gtaaagattt tgtaagttct tgtttttctt tctgtagcat      420

ggcaaggtca caagacatgt ttaagtaagg taggctcatg ttgcaaatcc tgttgtaaaa      480

cctgtcacgg tatgattaac tgcctttgtt ctgcttctgt aagactgctt tctcacctcg      540

caggttttgc gccaaaaacc cgacttgccc ctgcctgatg catgtataaa agtcaagccc      600

tgtctttgtt cagggctcag cctttggatg ttaatccgct gggccagtgg ccacctaaat      660

aaaaccttcc tgttgcaccc agtgatctct ccggcctcct gattcccaca acatataagc      720

attccttttt ctctgcaacc tagcccgcat ctgtcattga ctttttaaca ataggcattc      780

tgactggatg agatggtatc tcactgtggt ttttctctgc atttttctaa taattaacaa      840

cgtgaatttt gttttcatat gcttgtcagc cacatgtatg tcttcttttg aaaagtatct      900

gttcatgttt ttgcttactt tttaattagg tttttggttt tctttttgtt gttgttgttg      960

ttttctgaga tggagtcttg ctgtgtcacc aggatggagt gcagtggcat gatctcgact     1020

cactgcaacc tccacctccc aggttcagat gattcttctg cttcagtctc ctgagtagct     1080

gggatcacag ggaccattga catttatgga tgtggccata gaattctctt tggaggagtg     1140

gcaatgcctg gacactgcac agcagaattt atataggcat gtgatgtgag agaactacag     1200

aaacctggtt ttcttgggtg aaggtattgc tgtctctaag ccagacctga ttacctgtct     1260

ggagcaagga aaagagccct ggaatatgaa gagacatgag atggtagcta aacatttagt     1320

tatgttttat tattttgccc aacacctttg gccagagcag aacataagag attctttcca     1380

gaaagtgacc ctaagaagat atagaaaatg tggatatgag aatttacagt taagaaaagg     1440

ctgtaaaagt gtggttgagt gtaaacagca caaaggagat tatagtggac ttaaccaatg     1500

tttgaaaact accttgagca aaatatttca atgtaataaa tatgtagaag ttttccataa     1560

aatttcaaat tcaaatagac acaagatgag acatactgaa aataaacatt ttaaatgtaa     1620

agaatgtcgc aaaacatttt gcatgctttc acacctaact caacataaaa gaatccaaac     1680

tagagtgaat ttctacaaat gtgaagcata tggaagagcc tttaactggt cctcaaccct     1740

taataaacat aagagaattc atactggaga aaaaccttac aaatgtaaag aatgtggcaa     1800

agcctttaac cagacctcac accttattag acataagaga attcatactg aagagaaacc     1860

ctacaaatgt gaagaatgtg gcaaagcctt taaccagtca tcgaccctta ctacacataa     1920

tataattcat actggggaaa ttccctacaa atgtgagaaa tgtgttagag cttttaacca     1980

agcctcaaag cttactgaac ataagttaat tcataccgga gagaaacgtt atgaatgtga     2040

agaatgcggc aaagctttta accgatcctc aaaacttact gaacataagt acattcatac     2100

tggagagaag ctgtacaaat gtgaagaatg tggtaaagcc tttaaccagt cctcaaccct     2160

tactacacat aagagaattc atagtggaga gaagccctac aaatgtgaag aatgtggcaa     2220

agcttttaaa caattttcaa atcttactga ccataaaaaa attcatactg gagagaaacc     2280

ctacaaatgt gaggaatgtg gcaaagcttt taaccaactc tcaaacctta ctagacataa     2340

ggtaattcat actggagaga aaccctacaa atgtggagaa tgtggcaaag cctttaacca     2400

gtcctcagcc cttaatacac ataagataat ccatactgga gagaatcccc acaaatgtag     2460

agaatctggc aaagttttcc acctatcctc aaaacttagt acatgtaaga aaattcatac     2520

tggagagaaa ctctacaaat gtgaagaatg tggcaaagcc tttaaccgat cttcaaccct     2580

tattggacat aagagaattc atactggaga gaaaccctac aaatgtgaag aatgtggcaa     2640

agcttttaac caatcttcaa cacttactac acataagata attcatactg aagagaaaca     2700

gtacaaatgt gatgaatgtg gcaaagcttc tacctgatcc tcaaaactca ttgaacacaa     2760

gaaaattcat actggagaga aaccttacaa gtgtgaagaa tgtggcaaaa cttctaacca     2820

tttctcaacc cttactaaac ataagatgat tcatactgga gagaagttac acaaatgtga     2880

tgaatgtgac aaagctttta accaatcttc aaccctttct acacataaaa gaattcatac     2940

tggagagaaa ccctacaaat gtgaagaatg tggcagagct tttaattgat catcaaacct     3000

tattaaacat aagaaaattc atattggaga gaaaccctac aaatgtgaag aatgtggaaa     3060

agcttttaac cagttctcaa ctcttactac acataaaata attcatactg gagagaaacc     3120

atataaatgt gaagaatgtg gcaaagcttt caacctatac gtaaacctta ctacacataa     3180

gaaaattcat actggagaga aaccctacaa gtgtgaagaa tgtggcaaag cttttagcca     3240

agtgtcaact cttactatac ataaaagaat tcatactgga gagaaaccct acaagtgtga     3300

agaatgtggc aaagctttta accaagtgtc aactcttact atacataaaa gaattcatac     3360

tggagagaaa ccttacaaat gtgaggaatg tggcaaaact ttcagtcgat gctcaaaact     3420

tactacacat aagaaaattc atacaggaga gaaaccttac aaatgtgaaa aatgtgctaa     3480

agcttttagc cagtcttcaa ccctttctac atataagata attcacactg gagagaaatg     3540

ctacaaatgt gaagaatgtg gcaaagtttt taaccgatct tcaaacctta cagaccataa     3600

aaaaattcat acaggagaga aatcctacaa atgtgaagaa tgtgacaagg cctttaacct     3660

gtcctcaacg cttactaaac ataaggtaat tcatactgga gagaaactgt acaaatgtaa     3720

agaatgtggt aaagctttta aacagttctc acaccttgct atacataata taattcatac     3780

tggagagaaa ctctacaaat gtgaagaatg tggcaaagct tttaacttat cctcaaacct     3840

tactgcacat aagaaaaatc gtactggaga gaaaccctac aaatgtgaag aatgtggcaa     3900

agctaaccta tcatcaaccc ttactccaca taagacaatt catatttgag agaaaccctg     3960

caaatgtgaa gaatgtggca atgcttgtaa ctaaatctca aactttacta aacataagaa     4020

aattaatact ggaaacttta caaacctgaa agatgtgaca atgattttga caacaccttc     4080

aaacttttct aaacataaaa taaatcatac tggtgagaaa tcttaaaaat atgaagaatg     4140

gtacaaagcc tttaaatggt tgtcacactt gattgtaggt aagataattt atactggagg     4200

aaactcccag aagtgtgaag aatgtggcaa aacttttaat ttttcacacc ttatagcaca     4260

ggaaagcact tcagaaaaat tgtacaaata taaatgtgga aaagccatta atatctgctt     4320

acatcttact caacattaga gagttagtgc ttaataaaag cattataaaa gcaattagtg     4380

taaaatcaga aaatgaaagt tttttttttt tttttagatg gagtcttgct ctgtcaccca     4440

ggctggagtg cagtggtgtg atcttggctc actgcaacct ctgcctccca ggttcaagca     4500

attctcctgc cttagcctcc agagtagctg agactacagg cacacaccac cacatttggc     4560

taattttttt atttttagta gagactggct atcaccatgt tggccaggct gatcttgaac     4620

tcctgacctc aagtgatcca catgcctctg cctcccaaag tgctgggatt ataggtgtga     4680

gtcactgtgc ctgacaaata taagccttta aagagaagaa ggttttcatt ttgaagacaa     4740

acattaggta cataaagagg gttgtagtgt ctttatttgt atcacagatt ttattgtaca     4800

cattatgtac taaaggaaaa tcctgaagca gtgctcaaac tttgatcaac atcagggagt     4860

ttatattgga gaaaaactgc aaatgtaata tatttggaaa aacatttttc aaaaactact     4920

gcttagaaaa caccagggga tttatactaa aatatatttt tgcagatgca gtaagtataa     4980

aagaaattta atccaaaatt aagtgtgtgt aaatatcaga gaattcacag tagaaatatc     5040

taaggcactg acattttaga cattgaacta atcagtgtgc tgagtacaga aaataatcca     5100

aaattaaagt tggtagataa attatttata tataacttta aaagaggtag aaatattttt     5160

agttataatt acatttaaag tatacttttt tctttgaaaa aattacaaaa tttttaaaaa     5220

gtgaatgatg taattcaact caaattactt catgcttttc attctattgt attcacatgt     5280

gaaagcatgt gatcaattgc tgcttcatca aagatatgag acattctttt ttgttaggtg     5340

ggcaatattt tttacctttt ctatggaaga gtaaagacat tacaatgtag gatgcatgat     5400

aaaaatctaa gtggagaggc tctttgtgtt taatttataa tattgaatga tgtatgaggg     5460

aagtgttcag aggaatattc tgcattctag tgaaaatatc ttttatttta gttaaaatta     5520

aattaaaatt agtagtatat cattttacta actgtacttt tatgtaataa aatgcagcac     5580

atttaaaaaa ttttagatta ttgtgaactt aattttttaa ttaaactttt tttttaacat     5640

gttaagacca attgtgcatt cagtgaagta ttatcatgcc actaacttca acctatccca     5700

ccttactcaa gggtgttggt aaaagatagt aacaatgtac tatttaataa cagagtggac     5760

taacatctct aataatttct cttgccagtg actttaaact aaagaactta attaaagaac     5820

attgttccca taggttaaat ttttattctt tttcttattt aaacatattt ttcttaactt     5880

ttgtgggtac atagtgtgtg tatatattta tgccatatat ggcatatttt gatacaggca     5940

tatgaatagg tattaatcac atcagggcaa atgaaatatc catcaactcc agcatttatc     6000

atttgtatta caaaccgatt ctacactttt agttacttta aaatgtacaa gtaaattgct     6060

attgactata gggtcatttt catgggtata ataaaaatta tatacaagta taaataaaat     6120

cctgagtctt aaaattctga gtcctgctta aacattttaa aaattttgtt atgtattttt     6180

ctttgaacat gtctctctgc ctgcaaacat aacagaattt tagtattggt ttacatagag     6240

ttaactatac ccatatatta ctctaaaaat aaatgttaag tgcaagaaag ttatggactg     6300

tttttgtgtg agtgtgagtt tgtacctatt ttcaaaagaa aagagcaata ttggagcaaa     6360

acaaatattt taataaagta atgtactaga caactgaaaa cttc                      6404


<210>  2485
<211>  2146
<212>  DNA
<213>  homo sapiens

<400>  2485
tgcgtgccgc cgttgatccg gtgctgcagt gaggaggtgg ttcttgcccg tgttgtgtgt       60

gtgtgtgagt gagagagcga gtgagtgagt gagtgagtgt gtgtgtgggg gggactcggc      120

ttgttgttgt cggtgacttc cccctcccct tcaccccttc ccctccccgc cgccgctgca      180

gtggccgctc cctgggccgt aggaaatgag cgataacgat gacatcgagg tggagagcga      240

cgaagagcaa ccgaggtttc aatctgcggc tgacaaacgg gctcatcata atgcactgga      300

acgaaaacgt agggaccaca tcaaagacag ctttcacagt ttgcgggact cagtcccatc      360

actccaagga gagaaggcat cccgggccca aatcctagac aaagccacag aatatatcca      420

gtatatgcga aggaaaaacc acacacacca gcaagatatt gacgacctca agcggcagaa      480

tgctcttctg gagcagcaag gggaaagcga gagctgatca agttctttgt tcctggggaa      540

ttcacttctc ttcctccctc atggaagatg caagtaaaag gaaatgcaag taaccacctg      600

gtccgtgcac tggagaaggc gaggtcaagt gcccaactgc agaccaacta cccctcctca      660

gacaacagcc tctacaccaa cgccaagggc agcaccatct ctgccttcga tgggggctcg      720

gactccagct cggagtctga gcctgaagag ccccaaagca ggaagaagct ccggatggag      780

gccagctaag ccactcgggg caggccagca ataaaaactg tctgtctcca tcgtctcatc      840

ctcctttcag ttcgttggta gagccctcag aaccatttaa gagactcttt atttttctct      900

ttctcccttt tttttttaaa tttttatttt tacgtagaag ctcttggaca acagctctcg      960

ttctccttcc ccatttccac tgtatatttt ttaatgtatt cccttcaggg attccctgtc     1020

cccaacagga atttttaaac caaaacaccc caacttggca gctttttctg tggaggacag     1080

acggccggcc ggacctctga gcacatagtg tcctgcccac cctaccagct cctccagccc     1140

tgccgggcac atgcccgggg gacgcctgcc ctgcccaggt ggcctcctgg cccgccctca     1200

cctctgatag actttgtgaa tctgaactgc tctactttga gaagatgacc ggtttggagt     1260

aatcagaatg aaccctcctc ctttttaagg gttttttttt tttccttttt ctaaaaagct     1320

atgtatcgct cctattgaaa gaccagatcc ttagagaagt ttgtggtata aaaaggaagt     1380

ggggacagat tcgcagcaca gagtcgctgg catgtttcac tcctgcttct ctcagccagc     1440

tgtttaagcc tgcggcgcca gcctcacgga gggccgtgtg acactctcgt ggtatgtatg     1500

ggagatggca gcagtgaagc agcagccacc agggagtggc catttggggt tgggacaggg     1560

agggtgtttt gggtggcata gaggttttgt attgagggcc agtgatgatg ttttgatatt     1620

tatttcctgc tacttaaatt tgaatctgag tgaattgtac ctatttctga tgatgtcggt     1680

cttgcaaagc gacagattca taaagtaatg atgaaatctt tctttcttcc cgtgtgtatt     1740

tctaagaaat agagccaact gattttgtat gtaaatacca agagcaattt acctggtact     1800

aaacccgcac cccagtgcgg acccttccca gccctcatcc cacttccttt cctactgtcc     1860

tggaacctgt ctccattgtg tgatccagcc ctggttctgg ctgtggtcag cagatgccag     1920

tgaagggttt tgtgtgttta ggcctcattt ctttgtcttt ttcctactcc gttcctggca     1980

tttgctgatt tctagtgtat actctgtagt ctcagttcgt gtttgattcc attccatgga     2040

aataaaaagt atgttgtaca tactgccgaa gaattgtctt gcaagttaag gcttccccct     2100

ttactataag actataaata aaaacttatt ttatccttct taaaaa                    2146


<210>  2486
<211>  2331
<212>  DNA
<213>  homo sapiens

<400>  2486
ttccccactc ccccgccctc cccagggccc tgggaagggg ctcagcgtgg gaaaggatgg       60

ttgagtttta accagaggca aagcgtgagc gggatcagtg tgtgcggaac gcaagcagcc      120

gagagcggag aggcgccgct gtagttaact cctccctgcc cgccgcgccg accctcccca      180

ggaaccccca gggagccagc atgaagcgag ctcaccccga gtacagctcc tcggacagcg      240

agctggacga gaccatcgag gtggagaagg agagtgcgga cgagaatgga aacttgagtt      300

cggctctagg ttccatgtcc ccaactacat cttcccagat tttggccaga aaaagacgga      360

gaggaataat tgagaagcgc cgacgagacc ggatcaataa cagtttgtct gagctgagaa      420

ggctggtacc cagtgctttt gagaagcagg taatggagca aggatctgct aagctagaaa      480

aagccgagat cctgcagatg accgtggatc acctgaaaat gctgcatacg gcaggaggga      540

aaggttactt tgacgcgcac gcccttgcta tggactatcg gagtttggga tttcgggaat      600

gcctggcaga agttgcgcgt tatctgagca tcattgaagg actagatgcc tctgacccgc      660

ttcgagttcg actggtttcg catctcaaca actacgcttc ccagcgggaa gccgcgagcg      720

gcgcccacgc gggcctcgga cacattccct gggggaccgt cttcggacat cacccgcaca      780

tcgcgcaccc gctgttgctg ccccagaacg gccacgggaa cgcgggcacc acggcctcac      840

ccacggaacc gcaccaccag ggcaggctgg gctcggcaca tccggaggcg cctgctttgc      900

gagcgccccc tagcggcagc ctcggaccgg tgctccctgt ggtcacctcc gcctccaaac      960

tgtcgccgcc tctgctctcc tcagtggcct ccctgtcggc cttccccttc tctttcggct     1020

ccttccactt actgtctccc aatgcactga gcccttcagc acccacgcag gctgcaaacc     1080

ttggcaagcc ctatagacct tgggggacgg agatcggagc tttttaaaga actgatgtag     1140

aatgagggag gggaaagttt aaaatcccag ctgggctgga ctgttgccaa catcacctta     1200

aagtcgtcag taaaagtaaa aaggaaaaag gtacactttc agataatttt ttttttaaag     1260

actaaaggtt tgttggttta cttttatctt ttttaatgtt tttttcatca tgtcatgtat     1320

tagcagtttt taaaaactag ttgttaaatt ttgttcaaga cattaaattg aaatagtgag     1380

tataagccaa cactttgtga taggtttgta ctgtgcctaa tttactttgt aaaccagaat     1440

gattccgttt ttgcctcaaa atttggggaa tcttaacatt tagtattttt ggtctgtttt     1500

tctccttgta tagttatggt ctgtttttag aattaatttt ccaaaccact atgcttaatg     1560

ttaacatgat tctgtttgtt aatattttga cagattaagg tgttgtataa ataatattct     1620

tttgggggga ggggaactat attgaatttt atatttctga gcaaagcgtt gacaaatcag     1680

atgatcagct ttatccaaga aagaagacta gtaaattgtc tgcctcctat agcagaaagg     1740

tgaatgtaca aactgttggt ggccctgaat ccatctgacc agctgctggt atctgccagg     1800

actggcagtt ctgatttagt taggagagag ccgctgatag gttaggtctc atttggagtg     1860

ttggtggaaa ggaaactgaa ggtaattgaa tagaatacgc ctgcatttac cagccccagc     1920

aacacaaaga atttttaatc acacggatct caaattcaca aatgttaaca tggataagtg     1980

atcatggtgt gcgagtggtc aattgagtag tacagtggaa actgttaaat gcataaccta     2040

attttcctgg gactgccata ttttctttta actggaaatt tttatgtgag ttttcctttt     2100

ggtgcatgga actgtggttg ccaaggtatt taaaagggct ttcctgcctc cttctctttg     2160

atttatttaa tttgatttgg gctataaaat atcatttttc aggtttattc ttttagcagg     2220

tgtagttaaa cgacctccac tgaactgggt ttgacctctg ttgtactgat gtgttgtgac     2280

taaataaaaa agaaagaaca aagtaaaaaa aaaaaaaaaa aaaaaaaaaa a              2331


<210>  2487
<211>  4604
<212>  DNA
<213>  homo sapiens

<400>  2487
gctcttcttc cttccttctc cagtcccttc cactgtgcgt cttctgtccc ccgttcttcc       60

ccagcggacc cctctttcga gactccctag tggggtcccc agctcccggg cgatcctgcc      120

cttgccgagc gcgttttctg gagtcacctg ggggagggga gtcctgggca gggccgggct      180

ggggaagacg cctggggcac tgcccggcgt taacaaaggg agccgatacc gaccggcgtg      240

ggcgcggagc gggcggccgc caccgagcgt gctgagcaac cgcagcctcc gcggccgaga      300

gtgcagcgag caaggggaga gccagttgcg cagagccctg caaccagcag tccagggaga      360

agtggtgaat gtcatggagc ccagctgaaa tggactggcc cccttgagcc tgtcccaagc      420

cctggtgcca ggtgtccatc cccgtgctga gatgagtttt gatcatcctg agaaaaatgg      480

gccttggcct gcagacccaa taaaccttcc ctcccatgga taatagtgct aattcctgag      540

gacctgaagg gcctgccgcc cctgggggat tagccagaag caggcttgtt ttcctgctca      600

gaacaaagtg acttccctga acacatcttc attatgattc acaccaacct gaagaaaaag      660

ttcagctgct gcgtcctggt ctttcttctg tttgcagtca tctgtgtgtg gaaggaaaag      720

aagaaaggga gttactatga ttcctttaaa ttgcaaacca aggaattcca ggtgttaaag      780

agtctgggga aattggccat ggggtctgat tcccagtctg tatcctcaag cagcacccag      840

gacccccaca ggggccgcca gaccctcggc agtctcagag gcctagccaa ggccaaacca      900

gaggcctcct tccaggtgtg gaacaaggac agctcttcca aaaaccttat ccctaggctg      960

caaaagatct ggaagaatta cctaagcatg aacaagtaca aagtgtccta caaggggcca     1020

ggaccaggca tcaagttcag tgcagaggcc ctgcgctgcc acctccggga ccatgtgaat     1080

gtatccatgg tagaggtcac agattttccc ttcaatacct ctgaatggga gggttatctg     1140

cccaaggaga gcattaggac caaggctggg ccttggggca ggtgtgctgt tgtgtcgtca     1200

gcgggatctc tgaagtcctc ccaactaggc agagaaatcg atgatcatga cgcagtcctg     1260

aggtttaatg gggcacccac agccaacttc caacaagatg tgggcacaaa aactaccatt     1320

cgcctgatga actctcagtt ggttaccaca gagaagcgct tcctcaaaga cagtttgtac     1380

aatgaaggaa tcctaattgt atgggaccca tctgtatacc actcagatat cccaaagtgg     1440

taccagaatc cggattataa tttctttaac aactacaaga cttatcgtaa gctgcacccc     1500

aatcagccct tttacatcct caagccccag atgccttggg agctatggga cattcttcaa     1560

gaaatctccc cagaagagat tcagccaaac cccccatcct ctgggatgct tggtatcatc     1620

atcatgatga cgctgtgtga ccaggtggat atttatgagt tcctcccatc caagcgcaag     1680

actgacgtgt gctactacta ccagaagttc ttcgatagtg cctgcacgat gggtgcctac     1740

cacccgctgc tctatgagaa gaatttggtg aagcatctca accagggcac agatgaggac     1800

atctacctgc ttggaaaagc cacactgcct ggcttccgga ccattcactg ctaagcacag     1860

gctcctcact cttctccatc aggcattaaa tgaatggtct cttggccacc ccagcctggg     1920

aagaacattt tcctgaacaa ttccagcctg ctccttttac tctaggggcc tctgtcagca     1980

agaccatggg gacttcaaga gcctgtggtc aggaaatcag gtccagcctt ccctgtagcc     2040

agacagttta tgagcccaga gcctcctgcc acacacatgc acacatatct agcattcttt     2100

ccagacagca tcctccccgc cttccacctt ggtagatgca aggtctatct ctcccatcag     2160

ggctgccaaa gctgggcttt gtttttccca gcagaatgat gccattctca caaaccaatg     2220

ctctatattg cttgaagtct gcatctaaat attgatttca cgttttaaag aaattctctt     2280

aaattacaat tgtgcccaat gcagggtggc tctggggggc aagtaggtgg tacaggggat     2340

tggaaacatg ctccgcgcct ccagagaaaa gttgctcccg aggtccatgc ccctggaacg     2400

tgttcctatc actctggctg gttgggctgg tccttagact gggtgcttat gattaaaggg     2460

tcttggttag cccactttcc ctctccatgt ggagatggaa ggtagagaag gatacagtgt     2520

ctatcctcaa gttgctacgg ttcagtgaga gaggcagaca tctgaacagg caggtaggat     2580

tcagtgtgct cagtgcactg gggatttgga gagagatggg cttgctctct ctgtgcaccc     2640

aggagggcca cgcacttaaa actgtgtttg tggatcagag aaggctttat agcacagggg     2700

gcattcagat gagtcttaga ggaagagaag aaacatggca agcagattac atctgagccg     2760

tttgaattgt gtttttcttt cttcccatgt ttattttcta agatctacct gaacttagag     2820

actcaagata tttttttagg aaacctccta cccatgtctg aggtagcaag tgcagcctca     2880

cgacagatac caggcaatcc agagccacaa aacgtgattc ctccaggctc tgcctggcct     2940

gaccctgtcc tgtcagctgg gtttacatac cagtcccatt cttccttttc aatacctacc     3000

cccaaatctt ctcctaacca ccatctgttt ttttttttta aagcattttt tgctttaaaa     3060

gcatcctgac cccaatttct ttgagctcac gggccttttg ctgaaggtct ctcagggtgt     3120

agtggtgtgg ctctctggac ttaacgtcac tctcagaggt cagaaccttg gagatcagaa     3180

ctgattctca ccaggtgtga gaggtgtggt agcagattgc aatgctctgc acctcttcct     3240

tgcaagtgag caacttcagg ctctctgggc agaggctggc ccactgtagt ttgcagacat     3300

gctctccaga tggttttact aagtcccctc tccctgatag ggaatcctgc tggaccagcg     3360

cagccctggt gtggagaggt taaaagactt gcacaggatc accaagtcat gctgtagagc     3420

caggattcct agacccaggg ctctgcactc tcaaggctgg ccccatgtgc tcaaggggat     3480

ctaatgtttg ggctccaaac taaccatctc ggagctgggc tcctcattta ctgccaaacc     3540

ctcagcttat gtagctagaa agggccctgg agtgagaaag cctggatttt caaattgatg     3600

ctcccctact gactagctgt gccactctgg gcaaatgctc ttccttgagc ctgtttccac     3660

acctgtaaag tggggatgat gatcctatct cactgctttt gtgaggatta caggaaagca     3720

cctgtcctgg ctctgtacct ggcacgtagt aggtgctcag ttcatgctgg tttccttcct     3780

gcctttagta gggacctgct ctgtgctcac acctcggctg catgcaccct gctgtgacgg     3840

aggctagtgt ggaagaggtc ctgtcctcag ggaattaact gtcttattgg gagacaacaa     3900

ctgtcctcct tggaacaccc aagaaaccat gcaaagcagt ggacaacaca gaacacgccc     3960

tcctcctcgc tgcctgcagc tccaatctga ttctgcttgg gaatgggcgg agcacgtggg     4020

ctgcttaact gctgtatagg acaagcccct tacccctctc tgggcccatg aattcctggc     4080

ttggtttatg ttctgatttg acacactgat tttaatcttc gaatcatgac actgagtgca     4140

gaggaggtgg cattccgaca gcaggacata catgttggtg tgaagactgg gacgacactg     4200

ggtagaatct agtttttaat tattattaat ataaaggatc aaattaattt aaatatgatt     4260

ctgaagtcta cagaactttt agttctgtgc tgtctatgtg gacactttgg taaaatgcaa     4320

attatgatat ggacgttatc attggtctgg tgagatgttt catatttgtg acagttaatt     4380

taaaaattat gagttaatgc tgcctgtgtc tatggggttc tgtcttcttt gatagccatc     4440

tattcatctg gatcatggga ccctctctaa tccttccacc aatcaaataa gctattgcta     4500

ttggtttgga gttgagatat cagtctcgga aacttctgaa aaatgctaat aattacccaa     4560

ggattatgtc aaattttaaa ataaatgtgt gtgtgtttct ttaa                      4604


<210>  2488
<211>  2766
<212>  DNA
<213>  homo sapiens

<400>  2488
agaaggcgcg atgttgacgg ggtcctaaga tggctgctgg gcgaccactt cctgacagct       60

ccagttaatg ggactgccag caggctagac atccttcgcc ggaatgtgca gcgcttagtt      120

ctgtgcccgg gaggggcttc tctctctttt gggattggag tgtggcattg ccgccagaaa      180

gcctgcagaa ttccgggttg tgcagccaag caggaacggt gtacctttct agacccatcc      240

tcttgcaatc ttggacccta agaaaagatg tggagtgggc tgctacctcc tggcctaaat      300

gaaagtgacg ctgagtcaaa ctcggaagat gaagctacgt tggagaactc tggacttaac      360

ttacaggaag ataaagagga tgagagcatc agaaaaacag aaatcataga tttctcaaca      420

gatgaaccaa aaactgaaac agagtcaaat gtaaatgcct atgaagagtg tccttctgga      480

attcccatag atatgtggaa taaatttcaa gaattgcata aaaaacattc tgaacagaaa      540

agcacaacct caagattcag agggaaaaga agaaaacgct ccagaaaaga taaattgaag      600

aatgaaaaag aattacatag tgaaccgtcc tcaaatgaaa cccagtggaa agagcttact      660

cagtattttg gagtcaatga tagatttgac ccgcctgtta aaaggaaaaa agttgagaag      720

tcaggccttg aaaagaggat agaccaggct gtggaggagt ggaatattga gaaggctgag      780

gaactcagca accagctagc tactcgagag cttggtgtaa aaattgccaa agcagttgcc      840

tgccacaact ttgtaaaagc caaaaaggag gttgaaaatt cacaggctgc ccgaaaaaag      900

aagaaacttg catgggggtt tgaagcaaag aagagatggg aaaccaaaag caacatggga      960

tacatgtaac ttgccagagt gcttcaagac atttgtagac tcaaatgctc aatttactga     1020

gaatgttttc ctgcctatgt taatatgtca gaaaattgat agcactaaaa caaaaataag     1080

cataaaattt gggattttga ttatcagctc ttttcagtct ttctttaagg actttgtcct     1140

attgaagtga ataaaatgaa gcattctgtt atttgtataa gaaatgtaag aaaaaaaata     1200

tagaaagaag aggataggat tttgtttatt tgtatggatg gacccttggt ataaaatcac     1260

ttttggcgct ttccattcat ttggtttagc acagccagtg agcttctcgt actttctttc     1320

tttttttttt tttttttgag acagagcctc gcttgctctg tcacccaggc tagagtgcag     1380

tagcacgatc ttggctcact gcaaccactg cttcctgggt tcaagtgatt ctcatgcctc     1440

agcctcctga gtagctggga ttatggacaa atgccaccac acccggctaa tttttttttt     1500

ttttttgtat ttttagtaga gacagagttt tgctgtgttg gtcaggctgg tcttgaactc     1560

ctggcctcat atgattcacc tgcctctgcc tcccaaagtt ctgggagtac agacatgagc     1620

taccatgctg cccttgtatt ttcttatctg tacccagtgt aactacacgt ttactggaac     1680

tgtgttttta agactgacag ttgtttataa tggattagtc gtaagtacca aaaagtctca     1740

gttgatatta tctttacaaa tgacttgacc ttaatgttat aaaagtagtt actgtttttt     1800

tttaattgga ggcagacttg atatttcaga gttgcatagt aaaagcaatt tgttaatttt     1860

tgtgtacttt cagataaact attacaataa agaaaggagc agaatgtagt atttggaaga     1920

tgatttaaat tcagcaacgc ctaaaaatgt cttcctaagt atttttctca gccatgtcat     1980

tctttaaatt atgagatggt tcttagaaga gaaaatggtg taattgtatt aaacagacaa     2040

ttataactca agataatata actttgaacc ttctaagaac tgatttgttt ggttttcctc     2100

ccattcccca ttcctcctta aaagattgaa tgaattaatg agcagaaaga gaggattggt     2160

aacatgggaa atcgttttca ttagatgtac atttcctggt tctgacagga aaggggctcc     2220

agaaaatcat aaaacaagca ggtgaacaag accaggtgtg tcggcacctc cctgctcagt     2280

gcccagcgga ggtaaagaac cactcagcat ggtttttgtc agttcacctc ttctgtcgtt     2340

gtcagaggtt tcctacctgt ctgatataaa ctttctctgg gttgataata taaattcaga     2400

aacatgtaaa atgaatcatg attatattac tgttattttt agacttaaaa tagtaacaaa     2460

attttattta tggtggcaca tttaatggct ttttttttct gtgttctgga ataagagaat     2520

acctagctac tatttaagca tccaaaaatc atatcttgct ttcatttagt tgagaaaagc     2580

cagcatagag aaagcaaagt tttagaatat tatgtgtcat actaattcag tatccagacc     2640

aaatgttgga aagtcttatt ttatgattta atatcccttg ttccatttta cagatatgat     2700

catgtaaaac ttacctacaa tattcatttc aaactgctaa attaggtaaa tacagacttt     2760

tagtat                                                                2766


<210>  2489
<211>  2538
<212>  DNA
<213>  homo sapiens

<400>  2489
gtgagcgggc ggccggccgg acagactgac gtgtgagctg catcgcggga ggcgcatggc       60

ggggatggcg ctggcgcggg cctggaagca gatgtcctgg ttctactacc agtacctgct      120

ggtcacggcg ctctacatgc tggagccctg ggagcggacg gtgttcaatt ccatgctggt      180

ttccattgtg gggatggcac tatacacagg atacgtcttc atgccccagc acatcatggc      240

gatattgcac tactttgaaa tcgtacaatg accaagatgc gaccaggatc agaggttcct      300

tggggaagac ccaccctacg aagttggaat gagaccatca gatgtgataa gaaactcttc      360

tagatgtcaa cataaccaac cttataaaga ctaaaattca tgagtagaac aggaaaatca      420

tcctgactca tgtgttgtgt tctttatttt taattttcaa agaggctctt gtatagcagt      480

ttttgtctat tttaacattg tagtcatttg tactttgata tcagtatttt cttaaccttt      540

gtgactgttt caatattacc cccgtgaaag cttttcttaa tgtaactttg agtacatttt      600

aattgccttc tatttttaaa actcaaaatc attagttggg ctttactgtt cttgctattg      660

tatggcatat acatctgcct ggatatattt ctactcttga ccaaagtttt gtaaagaaca      720

atataagatt tcgggtaggg gtatggggag ggaagatatt ttattgagaa ctacttaaca      780

aaagatttat ctgtaagctt gaactcagga gtacagtttt agctatctag actctaacag      840

cttttgcttt aaaattatta aagtgtttct taatgaaaaa gaaaagatct tgctaaagtt      900

aaaataagga acatttcacc ttttaaatat ttaattctta tgtggactta tttccagaaa      960

actttggtga taattcttga gacaaaaggt ggttaagtag cattattatg taatgcttat     1020

ataccataga gtttttaata gaagagaaat ccatttcctc cgagggtcac tattaacaat     1080

gtacttcctt aaatttagtt taatgattgt aatgggtgct gcatttgcac attgcattaa     1140

gttatgatga gacgaattgt tgttaaaaat tatagcaaaa agaaatgtaa acttggttaa     1200

aatcctttca ctctttgtat tgtttttttt aaggttttta ttccttaaat gtaaaatgac     1260

tacctaattt tttgatgtaa atacattaaa ttcaaagaga aaaaaaatca gctgatgtag     1320

cagtatatct tttccttgat ggttaaatat tgatctagta tttatattgc tgaattattt     1380

tctgtggagg accagataag cagtaagtat gtcttatcct atatgttttg caacataaaa     1440

atattgctaa ttgaaaagaa ttaggcaatt atgtgtgttg ctgggttgtt tttttgtttt     1500

tttttttttg agacggagtc ttgccctgtc gcccaggatg gagtgcaaca gcatgatctc     1560

ggttcactgc aacctccatc tcctgggatc aagtgattct cctgcctcag cctcctgaat     1620

agctgggatt acaggcacct gccaccatgc ctggctaatt ttttgtatct gtagtagaga     1680

cggggtttca ctgtgttggc caggatggtc tcaaactcct gacctcctga tccacctgcc     1740

tcggcctccc aaagtgctgg gtttacaggc gtgagccacc gcgcccggcc aaaattgagg     1800

tattttttgc cctacgtttt aaggactaga cttttgaagt attttatagt ctagaggtct     1860

caagtaatat atatgtgttt aatattttta gagccaattg ataccacaat tagataggag     1920

tagtgagaat aatatggaat tacttggttt gaagtagtta aaaattggat atggttatat     1980

ctgagctgta gtcatattat ctcaagaaaa ataatacgag gatttaacat aagatttgtt     2040

ctattaatgc ccaaatttgg ctttcctcta ctatccccca tagagaacca ctaacaagtg     2100

gatgtctaat attcctctgg tgagttgaag gcaggagaag ttgagaatca ttagtttcaa     2160

tgagtatcca ggtgacctat cctggccctc tactcagaaa ccggcaattt gtcttcactc     2220

tgagattcat taaattgctg ttgtataact gatggttatt atgaacactg acctgtgaga     2280

catatggaag ataaagtttg gtcttacagg aaatcttgag gagagtcaaa agagaaatgg     2340

gagatgtctc ttgagaggtg atcagagaag tttatgctca ctgtctgatg caaatgtctg     2400

gtctatttgt tagtaaataa cagggaaatc attttcactt tttgttaaaa ataaggtatt     2460

tacaagcata ccttgtagtt attgtgggtt cagtttcaga ccactgcaat aaagtgaata     2520

tctcaataaa gtgaaaaa                                                   2538


<210>  2490
<211>  4009
<212>  DNA
<213>  homo sapiens

<400>  2490
ggccggcggc cacgtgaccc accgcggcgg ggccggcggc ccagaaatag cagcggcggc       60

ggttccgccc gcgggcggcg cgagcgaggg gcagaggcga gagacgccgg cggggcgcgg      120

gcgcggcggc cccggaggat gctgctgagc cccggcactg cctggctgcg agcacatgat      180

ggcgatacgg gagctcaaag tgtgccttct cggggacact ggggttggga aatcaagcat      240

cgtgtgtcga tttgtccagg atcactttga ccacaacatc agccctacta ttggggcatc      300

ttttatgacc aaaactgtgc cttgtggaaa tgaacttcac aagttcctca tctgggacac      360

tgctggtcag gaacggtttc attcattggc tcccatgtac tatcgaggct cagctgcagc      420

tgttatcgtg tatgatatta ccaagcagga ttcattttat accttgaaga aatgggtcaa      480

ggagctgaaa gaacatggtc cagaaaacat tgtaatggcc atcgctggaa acaagtgcga      540

cctctcagat attagggagg ttcccctgaa ggatgctaag gaatacgctg aatccatagg      600

tgccatcgtg gttgagacaa gtgcaaaaaa tgctattaat atcgaagagc tctttcaagg      660

aatcagccgc cagatcccac ccttggaccc ccatgaaaat ggaaacaatg gaacaatcaa      720

agttgagaag ccaaccatgc aagccagccg ccggtgctgt tgacccaagg gccgtggtcc      780

acggtacttg aagaagccag agcccacatc ctgtgcactg ctgaaggacc ctacgctcgg      840

tggcctggca cctcactttg agaagagtga gcacactggc tttgcatcct ggaagacctg      900

cagggggcgg ggcaggaaat gtacctgaaa aggattttag aaaaccctgg gaaaacccac      960

cacaccacca caaaatggcc tttagtgtat gaaatgcaca tggaggggat gtagttgcat     1020

ttttgctaaa aaaaaaaaaa aacctttaaa aattgttgga tgtgtacaaa agtcttactg     1080

ccttattatg tgtatgggat tctaaagtgg cattccactt ggatttcctg tgctacctat     1140

ccaaattcca gtaactactt cagtgtcatt gcctttgtta cctaaccaac cttcactgaa     1200

aggcaaattt agttcaggag gttagttttt agctagcttt ggaagtaagc ctttatttat     1260

tactttttgg aggaaatcag agaagtgtca atggaccgtc actcagactg agacttgagt     1320

tattacagaa gccaggaaaa gtgtattaga aactgttgtc tacaccactt ttaattggtg     1380

aacaattttt ctaagttatg gtcatatata cccaaacaaa ccaaatcaaa ctaaattact     1440

gcatataatt ttgggattgg gtggcctagt ttgaaagagt gatttaagta atcactatgt     1500

aagtggtgag agatgcagga catacacatt attcaagaga ccacctgaca tgcatctcct     1560

ccgcaggaat acattcgtcc tctcttagag aagtttaacg cacatagtat tattttacta     1620

agagaatatc tcttggtgtc atatctaggg gaagagaatt aactagaatt aaatttaatg     1680

tttgaatcta aatcattggg caaacttcta ataataacaa ttaataatag gttacaggaa     1740

agccagccag aggaagtgtc agcactttaa aattctagac cccaaaaaac tacaaaatca     1800

gaaaaagtat ttttatgttt ctagcttgag gagaagggct ttagggctaa ccagaggtct     1860

gaccctagaa tgccaaggaa ctgagaatgg gctccgatga aaaccttcct tttcagattc     1920

cctgtctgct caattaaaga tgtttgaatc caaaggaagt caaggaagaa aaagcatgga     1980

aaggaagaga actgattcct actgaaaatt caaattctat taccattcta actttcataa     2040

aaagttggga tcaagaagca gctgatttcc tgccagggct tatattaggg ggtgattctt     2100

aaaggacatt aggattggtg ctcagaaatg gttaatcatg ctgtgtgcta gccagggcca     2160

gctggtacct tctttgccat gagcattcaa gggacggcta acctttattg acaatctata     2220

tcgcaaaagt caggaaagag gttgtgagct gattggatta aagacctggc acttcagtaa     2280

ctcagcacgc ttccacttca ctcaacttaa gagagttcat tgacagtgtt aggatgtgaa     2340

ggctgggaaa cacttatttt gcttcaagag ttccacttgg ctctcccaaa taggtacctc     2400

aaaaactgtt agcaagcggc atttggatgt cttgacaggg gctttgcagg gatttttagg     2460

gttttttcca cattgtccac attaatggtt ggcatgattg tgcttgcagg ccaagaaatg     2520

atcatacccc ttgccaaagg taaaaaaaaa aaaaaaaaaa tgagttgaaa attgaagtga     2580

cctctttcca gctgagttgc aggcttattt tgtaaccttt cctcatccag ttttccctga     2640

gaacctgggt ttatctctag atagctgttc aggtttttta gctgaggggt aagtatccta     2700

gctgagagtt ttgcatcttt gggctgggtt tgcagtggtt gtgttttgca taaaatgtct     2760

agtctttgcc acagatagtg agctacccac taatgagccc atggttttat ttcagaagca     2820

catgagggtg tgaaaccact ctgttacctt tctgtattgt cttagctatt caagccagtc     2880

agaggataat atatatattc tcatcagcac tcagagtagt cagtgaagag agtagatcac     2940

acttgggcac accaggattc acataaacat tgtatcttct ctgtggatgc tcaggccttg     3000

tctacaatga ggctttacaa ccttcctttg ttttggctcg ggattacttc ctggctgtct     3060

aataattgaa ccataaccat gtaatattat gtaaaggcct ggaaattact gttgctaaaa     3120

aaagtcatgt agtttcatgt agtgtagcat ccttggcatc gttttccaaa atttgttcct     3180

tctccctttt ttttttcttt cgtgtgtggc atgagtgtgt atctgtgtaa atatgattgt     3240

atatgtgtta ctccgatatg taatccattt cactggctga gtttggcccc tagccatgtg     3300

ttaatataaa gtaggcatgg cttcccaatg gaaatctctg agaatgacag tggagttgtg     3360

caagcatttt acattgccac ataattgact tgccatttta tggttaaaaa cggcacatta     3420

ggcagttgaa tatgacgtta ccttgcagac taaaaggttg aaggcccgaa actaactttt     3480

agctaacaat aagggctgtg ccccaatgga aactgagttc attttctgag aaaggtttgg     3540

atgactgaaa tatttcctct acagtcaagg actttggcat gtggtggctg aaactgagct     3600

tttttgtgtg ggctccagtt ctcactgttc tgcaatgctc atggcaagtt gaatggtgag     3660

ctagcttata aattaaagag ctctgaactg tattcagacc gactgggtat ctagcttact     3720

gttttaacat cattgttgaa accagaccct gtagtccagt ggtgctgccc tgttgtgcaa     3780

actgctcctt tttctcgtgt ttttgtaaag agcttccatc tgggctggac ccagttcttg     3840

cacatacaag acaccgctgc agtcagctag gacctttccg ccatgtattc tattctgtag     3900

taaagcattt ccatcaacaa tgcctaattg tatctgttat ttttggttta acacacactg     3960

attcatacta ataaatattt tcagttttac cgttaaaaaa aaaaaaaaa                 4009


<210>  2491
<211>  4504
<212>  DNA
<213>  homo sapiens

<400>  2491
ggggcggggc ggcgcggcgc ggagccgagc aggacggccg ccatcttgcg cgcagctgga       60

gtcggtgcct gaggttgcag ccgagagtgt gcgccagccc gcggcccagc cgaagctctt      120

tcccgccgcc tctccgcgcc tcgcccaggt tcagctccgc ctgaccctcc gcttggcacg      180

gtcccctgac cctcagtccg gcctggtccg gccttccagc cgccccgggg acgatgaacg      240

gaggataaat ggtgcccaag gcagacagcg gcgccttcct gctgctcttc ctgctcgtgc      300

tcactgtcac cgagccgctg cggccagagc tgcggtgcaa ccctgggcag tttgcgtgtc      360

gcagcggcac catccagtgc atccccctcc cctggcagtg tgacggctgg gcgacttgcg      420

aggatgagag cgacgaagcc aactgtccag aagtgaccgg ggaggtgcgt cctcatcatg      480

ggaaggaggc tgtggatccg cggcaggggc gggccagagg aggcgaccct tcgcacttcc      540

acgcggtgaa cgtggcgcag cccgttcgct tcagcagttt cctagggaag tgcccgacag      600

ggtggcacca ctacgaaggc acggccagct gctaccgggt ctacctgagc ggggagaact      660

actgggatgc cgcgcagacc tgccagcgcc tgaatggctc tctcgccacc ttctccactg      720

accaggagct gcgctttgtc ctggcccagg aatgggacca gcccgagcgg agctttggtt      780

ggaaggacca gcgcaagttg tgggttggct atcagtatgt tatcactggc cggaaccgct      840

ccttggaagg tcgctgggag gtggcattca aaggctcttc agaggtgttc ctgcccccag      900

accccatctt tgcctcggcc atgtctgaga acgacaacgt gttctgtgcc cagcttcagt      960

gcttccattt ccccaccctg cggcaccacg acctccacag ctggcacgcc gagagctgct     1020

acgagaagtc ttcatttctg tgtaaaagaa gtcaaacatg tgttgacatc aaggacaacg     1080

tggtggatga agggttctac ttcaccccta agggggacga cccatgcctg agctgcacct     1140

gccatggagg ggagcctgag atgtgtgtgg ctgctctctg tgagaggccc cagggctgcc     1200

aacagtaccg caaggacccc aaagagtgct gcaagttcat gtgtctggac ccagatggca     1260

acagtctgtt tgactccatg gccagcggga tgcgcctggt cgtcagctgc atctcctcct     1320

tcctcatcct gtcactgctg ctcttcatgg tccaccggct gcgccagcgg cgccgggagc     1380

gcatcgagtc cctgattgga gcaaacttgc accacttcaa cctcggccgc aggatccctg     1440

gctttgatta cggcccagac gggtttggca cgggcctcac gccgctgcat ctttctgacg     1500

acggagaggg tgggactttc catttccacg accctccacc tccctacacg gcatacaagt     1560

acccggacat cggccagccc gacgaccctc cgccgcccta cgaggcctcc atccacccgg     1620

acagtgtgtt ctatgaccct gcagacgatg atgcttttga gcctgtggag gtcagcctgc     1680

cagcccctgg ggatggtggg agtgaaggtg cattactccg gcgcctggag cagcctctgc     1740

ccactgcggg ggcctctctg gcagacctgg aagactctgc cgacagcagc agcgccctgc     1800

tcgtgccccc tgaccctgcc cagagcggga gcaccccagc tgcagaggca ctgccagggg     1860

gtggccgcca cagccgcagc tccctcaata ctgtggtgta gacggcctgg cctgtacccc     1920

aacggtctgg gagcacctgt ctgttgtaga aaacaccggt ccctggggag acttgaaagg     1980

cccctgtccc agcctggacg ccacgcactg ccgcacgtca ctggcgggct cgcgtgtgta     2040

catagagacc acagcccgcc ttctgccaaa agaagtgatg gcctgcaccg agcttccttg     2100

agggcttcag aaacatgcat agctttggat cactgtcttc tcctttataa atggcagaag     2160

agtgacaaaa ttcattcaga ccgcacatgt tagaggcagg gaatgaagaa ggtactgtgg     2220

gccatggcca cacctgatgc gtttttggtg ggcttacttg gtgcagtgtg ctgtccagag     2280

agacctgctg acccagtctg ggacaggcac agtgggagct gccacagtgc cccttgctgg     2340

ccgccctcag gagggggcct ctggaccgtc agtgtggcgt aggcagtggg tctgcttcag     2400

ggaggcagcc tcttgacttt gtcacaacgg ttgcactgaa gatggccccc acaagcccag     2460

ttgtgaatat caaggtgacc ctgcccctgg ctgggagctc ccctggggct ctggaacctg     2520

aagccctgag aaggagagct tggaaggagg ttgagctctt cactgtgtct ttccatctgg     2580

gctctgcagc ccagctctgt ggcaggaggc ctgaccccac cccatcagtc cctctcccag     2640

cattgctgtg catggctccc tcaggaagaa gctctggagt ggggccgagg ccccagatgc     2700

tctgctgggg tctggggact gagctgcctc ctgtctctcc actctggagc cctgggctct     2760

tgcctcctgt tgaattgccc ctgggcctgc ccccggcccc atttgtgcca taaagggttg     2820

cttcattgca ggaggggtgg ctgaaaccac catcctgggc tgcatctatc tccttaaagt     2880

ccactcctta catcaccgcc actactgcag ctcagtgccc agcggccgca tgcacacctc     2940

ccggcccctc ctcagcagcg caggggctgg gggcccttcc tggcaccctt ttgcctgacg     3000

gaccctgttg cctgctcctg ggcagtggtt ttgttgcctg acacagggcc tttaacattt     3060

ctgaggtttg gagattaagc gggttctgtg cgatttttag cacatccata tcttttctac     3120

gttgaatgtc tggatctttc ctttgtatgt ttgtgtctct gtgtgtgtat gtggccaagc     3180

gtctgcaggt gagggtggca catggaactt cacgggtcac tgggggccca ctcttccagg     3240

gtcatcgatg catcctgggc tgtgctgagg cagtgctgtc tcgctcagtc tttccagacc     3300

agcggggcag cacctgggag gcctgtctga agcatgcagt tctgtggtgc tgctcgggga     3360

tggactccat gcacagtcca cttcttgaca cattctcaca ctgtggctgg agacccattt     3420

tttccatccc atgtggaatg agaatcttga gttgcccaca gacagacttg acctttgtgc     3480

cagaactgtc cagagctgtg agttttgtta ctgaattgcc tgtccctgag cttggcctgc     3540

tggagcatga tgctggaggc tgtgtgcggg caggcttgtg ctccccttgg agaagggctg     3600

ctacttaaca aggaagtcct ggccacagga gtcccctact ggctgcagag gacgaagcag     3660

gaagcatgcc gtggatccca catgcactgg ggcagggcag ccaggttcca gagcagcagg     3720

catgtgcatt atgggtgcca ggtggccagt gagggcccga ggaccacgca gcagagtccc     3780

ccacgggcct gagcctgaga gctcagagga ttcctgccag gcctcagaac tgtgtgtgcg     3840

ggacagggtg gctggcacga gatgtgtggg actgggacgc ttcctttggg gaccagagga     3900

acattagggg ccggtcagac acgtaggggg cagtgaggaa acggggtaaa gtggaccatg     3960

caggctgcag agggtgggcc ttgggctggc cggggttgct gggtggcccc ttccccatgg     4020

gcctccacaa gcactcaggc cactggcacg ttgggccagg cagaaggtcc acatggcagg     4080

gctgcctgga acaccgctgc cactgtggct ccaggaggcc cttgggagca tgaggagagc     4140

tggactcgct catctgttct tgcaccacca tccagaatgc cccctttgca aggcctgctg     4200

cagtccccag tctgaccagc aagtcccggg gtcacccttg ctgaaccttg tgctccaggg     4260

gtcctcctcc tctaggacca gcttgccacg gtttctcaga gcccaggtgc cctctgacct     4320

gccatgcgga ggtgggattt gatactgtac attgtcttga tgcctgtttt tttatgtttt     4380

cattaagggt ttttagtttt tggttgggtt gacactaact tttcttaaga tgctgtgaga     4440

atcatttcat ccaaatgcca aataaacttg tgttccggaa gaggaaaaaa aaaaaaaaaa     4500

aaaa                                                                  4504


<210>  2492
<211>  4504
<212>  DNA
<213>  homo sapiens

<400>  2492
ggggcggggc ggcgcggcgc ggagccgagc aggacggccg ccatcttgcg cgcagctgga       60

gtcggtgcct gaggttgcag ccgagagtgt gcgccagccc gcggcccagc cgaagctctt      120

tcccgccgcc tctccgcgcc tcgcccaggt tcagctccgc ctgaccctcc gcttggcacg      180

gtcccctgac cctcagtccg gcctggtccg gccttccagc cgccccgggg acgatgaacg      240

gaggataaat ggtgcccaag gcagacagcg gcgccttcct gctgctcttc ctgctcgtgc      300

tcactgtcac cgagccgctg cggccagagc tgcggtgcaa ccctgggcag tttgcgtgtc      360

gcagcggcac catccagtgc atccccctcc cctggcagtg tgacggctgg gcgacttgcg      420

aggatgagag cgacgaagcc aactgtccag aagtgaccgg ggaggtgcgt cctcatcatg      480

ggaaggaggc tgtggatccg cggcaggggc gggccagagg aggcgaccct tcgcacttcc      540

acgcggtgaa cgtggcgcag cccgttcgct tcagcagttt cctagggaag tgcccgacag      600

ggtggcacca ctacgaaggc acggccagct gctaccgggt ctacctgagc ggggagaact      660

actgggatgc cgcgcagacc tgccagcgcc tgaatggctc tctcgccacc ttctccactg      720

accaggagct gcgctttgtc ctggcccagg aatgggacca gcccgagcgg agctttggtt      780

ggaaggacca gcgcaagttg tgggttggct atcagtatgt tatcactggc cggaaccgct      840

ccttggaagg tcgctgggag gtggcattca aaggctcttc agaggtgttc ctgcccccag      900

accccatctt tgcctcggcc atgtctgaga acgacaacgt gttctgtgcc cagcttcagt      960

gcttccattt ccccaccctg cggcaccacg acctccacag ctggcacgcc gagagctgct     1020

acgagaagtc ttcatttctg tgtaaaagaa gtcaaacatg tgttgacatc aaggacaacg     1080

tggtggatga agggttctac ttcaccccta agggggacga cccatgcctg agctgcacct     1140

gccatggagg ggagcctgag atgtgtgtgg ctgctctctg tgagaggccc cagggctgcc     1200

aacagtaccg caaggacccc aaagagtgct gcaagttcat gtgtctggac ccagatggca     1260

acagtctgtt tgactccatg gccagcggga tgcgcctggt cgtcagctgc atctcctcct     1320

tcctcatcct gtcactgctg ctcttcatgg tccaccggct gcgccagcgg cgccgggagc     1380

gcatcgagtc cctgattgga gcaaacttgc accacttcaa cctcggccgc aggatccctg     1440

gctttgatta cggcccagac gggtttggca cgggcctcac gccgctgcat ctttctgacg     1500

acggagaggg tgggactttc catttccacg accctccacc tccctacacg gcatacaagt     1560

acccggacat cggccagccc gacgaccctc cgccgcccta cgaggcctcc atccacccgg     1620

acagtgtgtt ctatgaccct gcagacgatg atgcttttga gcctgtggag gtcagcctgc     1680

cagcccctgg ggatggtggg agtgaaggtg cattactccg gcgcctggag cagcctctgc     1740

ccactgcggg ggcctctctg gcagacctgg aagactctgc cgacagcagc agcgccctgc     1800

tcgtgccccc tgaccctgcc cagagcggga gcaccccagc tgcagaggca ctgccagggg     1860

gtggccgcca cagccgcagc tccctcaata ctgtggtgta gacggcctgg cctgtacccc     1920

aacggtctgg gagcacctgt ctgttgtaga aaacaccggt ccctggggag acttgaaagg     1980

cccctgtccc agcctggacg ccacgcactg ccgcacgtca ctggcgggct cgcgtgtgta     2040

catagagacc acagcccgcc ttctgccaaa agaagtgatg gcctgcaccg agcttccttg     2100

agggcttcag aaacatgcat agctttggat cactgtcttc tcctttataa atggcagaag     2160

agtgacaaaa ttcattcaga ccgcacatgt tagaggcagg gaatgaagaa ggtactgtgg     2220

gccatggcca cacctgatgc gtttttggtg ggcttacttg gtgcagtgtg ctgtccagag     2280

agacctgctg acccagtctg ggacaggcac agtgggagct gccacagtgc cccttgctgg     2340

ccgccctcag gagggggcct ctggaccgtc agtgtggcgt aggcagtggg tctgcttcag     2400

ggaggcagcc tcttgacttt gtcacaacgg ttgcactgaa gatggccccc acaagcccag     2460

ttgtgaatat caaggtgacc ctgcccctgg ctgggagctc ccctggggct ctggaacctg     2520

aagccctgag aaggagagct tggaaggagg ttgagctctt cactgtgtct ttccatctgg     2580

gctctgcagc ccagctctgt ggcaggaggc ctgaccccac cccatcagtc cctctcccag     2640

cattgctgtg catggctccc tcaggaagaa gctctggagt ggggccgagg ccccagatgc     2700

tctgctgggg tctggggact gagctgcctc ctgtctctcc actctggagc cctgggctct     2760

tgcctcctgt tgaattgccc ctgggcctgc ccccggcccc atttgtgcca taaagggttg     2820

cttcattgca ggaggggtgg ctgaaaccac catcctgggc tgcatctatc tccttaaagt     2880

ccactcctta catcaccgcc actactgcag ctcagtgccc agcggccgca tgcacacctc     2940

ccggcccctc ctcagcagcg caggggctgg gggcccttcc tggcaccctt ttgcctgacg     3000

gaccctgttg cctgctcctg ggcagtggtt ttgttgcctg acacagggcc tttaacattt     3060

ctgaggtttg gagattaagc gggttctgtg cgatttttag cacatccata tcttttctac     3120

gttgaatgtc tggatctttc ctttgtatgt ttgtgtctct gtgtgtgtat gtggccaagc     3180

gtctgcaggt gagggtggca catggaactt cacgggtcac tgggggccca ctcttccagg     3240

gtcatcgatg catcctgggc tgtgctgagg cagtgctgtc tcgctcagtc tttccagacc     3300

agcggggcag cacctgggag gcctgtctga agcatgcagt tctgtggtgc tgctcgggga     3360

tggactccat gcacagtcca cttcttgaca cattctcaca ctgtggctgg agacccattt     3420

tttccatccc atgtggaatg agaatcttga gttgcccaca gacagacttg acctttgtgc     3480

cagaactgtc cagagctgtg agttttgtta ctgaattgcc tgtccctgag cttggcctgc     3540

tggagcatga tgctggaggc tgtgtgcggg caggcttgtg ctccccttgg agaagggctg     3600

ctacttaaca aggaagtcct ggccacagga gtcccctact ggctgcagag gacgaagcag     3660

gaagcatgcc gtggatccca catgcactgg ggcagggcag ccaggttcca gagcagcagg     3720

catgtgcatt atgggtgcca ggtggccagt gagggcccga ggaccacgca gcagagtccc     3780

ccacgggcct gagcctgaga gctcagagga ttcctgccag gcctcagaac tgtgtgtgcg     3840

ggacagggtg gctggcacga gatgtgtggg actgggacgc ttcctttggg gaccagagga     3900

acattagggg ccggtcagac acgtaggggg cagtgaggaa acggggtaaa gtggaccatg     3960

caggctgcag agggtgggcc ttgggctggc cggggttgct gggtggcccc ttccccatgg     4020

gcctccacaa gcactcaggc cactggcacg ttgggccagg cagaaggtcc acatggcagg     4080

gctgcctgga acaccgctgc cactgtggct ccaggaggcc cttgggagca tgaggagagc     4140

tggactcgct catctgttct tgcaccacca tccagaatgc cccctttgca aggcctgctg     4200

cagtccccag tctgaccagc aagtcccggg gtcacccttg ctgaaccttg tgctccaggg     4260

gtcctcctcc tctaggacca gcttgccacg gtttctcaga gcccaggtgc cctctgacct     4320

gccatgcgga ggtgggattt gatactgtac attgtcttga tgcctgtttt tttatgtttt     4380

cattaagggt ttttagtttt tggttgggtt gacactaact tttcttaaga tgctgtgaga     4440

atcatttcat ccaaatgcca aataaacttg tgttccggaa gaggaaaaaa aaaaaaaaaa     4500

aaaa                                                                  4504


<210>  2493
<211>  10796
<212>  DNA
<213>  homo sapiens

<400>  2493
atgtgggggc ttttgatctg gacactgcta gctctgcatc agatccgcgc ggccagagcc       60

caagatgatg tgtccccgta tttcaagaca gagcctgtgc ggacacaggt gcacttggaa      120

ggaaaccgcc tggtgcttac atgcatggcc gagggcagct ggccactgga gttcaagtgg      180

ctccacaaca acagggagct gaccaagttc tccctggaat acagatacat gatcaccagc      240

ctggaccgca cccacgctgg cttttaccgt tgcatcgtgc ggaaccgaat gggggccctg      300

ctgcagcggc aaaccgaggt ccaggtggcc tacatgggga gctttgagga aggtgagaag      360

caccagagcg tctcccacgg agaagcagct gtcatccgtg ccccgcgcat cgccagcttc      420

ccccagccac aggtgacctg gttccgggac ggccgcaaga tcccgcccag cagccgcata      480

gccatcacgc tggagaacac ccttgtcatc ctgtcaacgg tggcccctga cgcaggtcgc      540

tactatgtgc aggctgttaa cgacaaaaac ggggataaca agaccagcca gcccatcacg      600

ctcaccgtgg agaatgtagg ggggcctgca gaccccatcg cacccaccat catcatccca      660

cctaaaaaca ccagcgtggt ggccggcacc tcagaggtta ccttggagtg tgtggccaat      720

gccaggcccc tgatcaagct acatatcatt tggaagaagg acggggtatt gctgtcgggc      780

ggcatcagtg accacaaccg ccggctcacc atccccaacc ccaccggcag tgacgccggc      840

tactacgagt gtgaggctgt cctgcgcagc agcagcgtcc cctctgttgt ccggggcgcc      900

tacctctcag tgctggaacc gcctcagttt gtcaaggagc cagaaagaca catcactgcg      960

gagatggaga aggtggtgga catcccctgt caggccaaag gtgtgccgcc gccctccatc     1020

acctggtaca aggacgcagc cgtggtggag gtggagaagt tgacccgctt ccggcagcgc     1080

aacgacgggg gcctgcagat cagcggcctg gtgcccgatg ataccggcat gttccagtgc     1140

ttcgcccgca atgcagccgg cgaggtgcaa acttccacct acctggctgt caccagcatc     1200

gcccctaaca tcaccagagg ccccctggac agcacggtga tcgatggcat gtcagtggtg     1260

ctagcatgtg agacctcggg ggcgccccga ccagctatca cttggcagaa aggggagcgc     1320

atcttggcca gtggctctgt gcagctgcct cgcttcacac ccctggagtc gggcagcctc     1380

ctcatcagcc ccacacacat ctccgatgcg gggacctaca cctgcctggc caccaactct     1440

cggggggtcg atgaggcctc agcagaccta gtcgtttggg ctcggacccg catcaccaag     1500

cccccccagg atcagagtgt catcaagggc acccaggcct ccatggtgtg cggagtgacc     1560

cacgaccccc gagtaaccat caggtacatc tgggagaagg acggggccac cctgggcacg     1620

gagagccatc ctcgtatccg cctggacaga aacggctccc tgcacatctc acagacgtgg     1680

tcgggagaca tcggcacgta cacctgccgg gtgatctcag caggaggcaa cgactctcgc     1740

agtgcccacc tgcgagtcag gcaactgccc cacgcgcccg agcacccagt ggccactctc     1800

agcaccgtgg aaaggcgagc catcaacctg acgtggacca agccctttga tggcaacagc     1860

cccctgatcc gctacattct ggagatgtcg gagaacaatg ccccctggac tgtactcctg     1920

gccagtgtgg accccaaagc tacctcagtg acagtcaagg gcctggttcc tgcacgctcc     1980

taccagttcc gtctttgtgc cgtcaacgac gtggggaaag gacagttcag caaagacacc     2040

gagagggtct ccctccccga ggagcccccc acggcccctc cacagaacgt catcgccagc     2100

ggtcgaacca accagtccat catgatccag tggcagccgc ctcctgagag ccaccagaat     2160

ggaattctca agggttacat catcaggtac tgcctggccg ggctgcccgt ggggtaccag     2220

tttaagaaca tcacggatgc tgatgtgaac aacctgctgc tggaggatct catcatttgg     2280

accaactacg agatcgaggt ggctgcttac aacagcgctg ggctgggggt ctacagcagt     2340

aaagtcaccg agtggacgct gcagggagtt cccacggtcc ctccgggcaa tgtgcacgcg     2400

gaagccacca attccacgac catccgcttc acctggaacg cccccagccc ccagttcatc     2460

aacggcatca accagggcta caagctgatc gcctgggagc cggaacagga agaggaggtt     2520

accatggtga ccgcccggcc taactttcaa gacagcatcc acgtgggctt cgtgtctggc     2580

ctgaagaagt tcaccgagta cttcacctca gtgctgtgtt tcaccacccc cggggacggg     2640

ccacgcagca ccccgcagct ggtgcgcacc catgaggatg tgcctgggcc cgtgggacac     2700

ctgagcttca gtgagatcct ggacacatcg ctgaaggtca gctggcaaga gccgggagag     2760

aaaaatggca tcctcacagg gtaccggatc tcctgggagg agtacaatcg aaccaacacc     2820

cgtgtgaccc actacctgcc caacgtgacc ctggagtacc gtgtcacggg cctcaccgcg     2880

ctcaccacct acaccatcga ggtggccgcc atgacctcaa agggccaggg ccaagtgtcc     2940

gcctccacca tctcctctgg ggtgccccca gaactcccag ggccccccac caacctgggc     3000

atttccaaca tcggcccccg ctctgtgacc ttgcagttca ggccaggcta cgatgggaaa     3060

acctccatct cccgctggct ggtggaagcc caggtaggcg tggttgggga gggagaggag     3120

tggttgctga tccaccagct ctccaatgag cccgatgccc gctccatgga ggtgcccgac     3180

ctcaacccct tcacctgcta cagcttccgc atgcgccagg tgaacatcgt gggcaccagc     3240

ccccccagtc agccttctag aaagatccag accctgcagg caccccctga catggcccca     3300

gccaatgtgt ctctgcgcac agccagtgag accagcctgt ggctgcgctg gatgcctctc     3360

ccggagatgg aatacaatgg gaaccctgag tccgtgggct ataagatcaa gtacagccgg     3420

tcagacgggc atggcaagac gctgagccac gtggtgcagg accgtgtgga gcgggactac     3480

accatcgagg acctggagga gtggacagag taccgcgtcc aggtccaggc cttcaacgcc     3540

atcgggagcg ggccctggag ccagacggtg gtgggcagga cccgggagtc agttccctct     3600

tccggcccca ccaatgtgtc tgcactggcc accacctcca gcagcatgct ggtgcgctgg     3660

agcgaggtcc ccgaggctga tcgcaacggg ctcgtgctgg gctataaggt gatgtataag     3720

gagaaggact cggacaccca gccccgattc tggctggtgg aaggcaactc gtctcgcagt     3780

gcccagctca ccggcttggg caaatacgtg ctctatgaag tccaggtgct ggccttcaca     3840

cgcatcgggg acggcagccc cagccaccct cccatcctgg agcggacgct ggatgatgtc     3900

ccaggaccac ccatgggcat cctgttccca gaggtgcgga ccacgtctgt gcggctgatc     3960

tggcagcccc ctgccgcccc caatggcatc attcttgctt accagatcac acaccggctc     4020

aacaccacca cggccaacac cgccactgtg gaggtgctgg cacccagcgc ccggcagtac     4080

acagccacgg gcctcaagcc agagtctgtc tacctgttcc gcatcacggc ccagacccgc     4140

aagggctggg gagaagctgc cgaggccttg gtggtgacca ccgagaagag agaccgtccg     4200

cagcccccca gcaggccgat ggtgcagcag gaggatgtga gagcacgcag cgtgctgctg     4260

tcctgggagc cagggagcga cgggctctcc cctgtgcgct actacaccat ccagacccgc     4320

gagctgccca gcggcaggtg ggcactgcac tcggcctccg tgagccacaa tgcctccagc     4380

ttcattgtgg acaggctgaa gcccttcacg tcctacaagt tccgagtgaa ggcgaccaat     4440

gacattggcg acagcgagtt cagcgaggag tcggagtcac tgaccaccct gcaggctgcc     4500

cccgatgaag cacccaccat cctctccgtg acgccccaca ccaccacctc cgtgctaatc     4560

cgatggcagc cgccagcaga ggacaagatc aatggcatcc tcctgggctt ccggatccga     4620

taccgggagc tgctctatga aggactgagg ggcttcacgc ttcgaggcat caacaaccca     4680

ggggccacat gggctgagct tacctccatg tactccatgc ggaacctgag ccggcccagc     4740

ctcacgcagt acgagctgga caacctgaac aagcacaggc ggtacgagat acggatgagc     4800

gtgtacaacg ctgtgggtga ggggccctcc agccccccgc aggaggtctt tgttggggag     4860

gcagtgccca cagcagcacc tcgtaacgtg gtcgtccacg gcgccacggc cacacagctg     4920

gacgtgactt gggagccacc tccgctggac agccagaatg gagacatcca ggggtacaag     4980

atttatttct gggaagccca gcgggggaac ctcacagagc gagtgaagac gcttttcctg     5040

gctgagaaca gcgtgaagct caagaacttg actggctaca cggcctacat ggtcagcgtg     5100

gccgccttca acgccgctgg ggatgggcct cggagcaccc ccacccaagg ccagacccag     5160

caagcagccc ccagcgctcc cagctcggtc aagttcagtg agctgaccac aacctcagtg     5220

aatgtgtcct gggaagcccc gcagttcccc aatggcatcc tggagggcta caggctggtg     5280

tacgagccct gcagccccgt ggatggagtc agcaagatcg tgaccgtgga cgtgaagggg     5340

aacagccccc tgtggctgaa ggtgaaggac ctggcggagg gggtgaccta caggttccgc     5400

atcagagcca agaccttcac ctacgggccg gagatcgaag ccaacgtcac cacgggcccc     5460

ggagaaggtg ccccaggacc gcctggcgtg cccatcatcg tgcggtacag ctctgccatc     5520

gccattcact ggtccagcgg agacccgggc aaagggccca tcacccgcta cgtcatcgag     5580

gccagacctt cagacgaggg actatgggac atcctcatca aagacatccc caaggaggtg     5640

agctcctaca cgttcagcat ggacatcctg aagccgggcg tgagctatga cttccgggtc     5700

atcgcggtca acgactatgg tttcggcacc cccagcagcc cctcccagtc tgtgccagcc     5760

cagaaagcca accccttcta tgaggagtgg tggttcttgg tggtcattgc cctggtcggc     5820

ctcatcttca tcctgcttct ggtcttcgtg ctcatcatcc ggggccagag caagaagtac     5880

gccaagaaga cagactcggg gaacagtgcc aagtctggag ccctaggcca cagcgagatg     5940

atgagcttgg atgaaagcag cttccctgcc ctggaactca acaacaggcg gctctccgtc     6000

aagaactctt tctgccgaaa gaacggcctg tacaccaggt ctccccccag gcccagccca     6060

ggcagcctgc actactcgga tgaggatgtc accaaataca acgacctcat ccctgcagag     6120

agcagcagcc tgacggagaa gccctcagaa atctccgact ctcagggaag tgacagcgag     6180

tacgaggtcg actcaaacca ccagaaggcc cactcctttg tcaaccacta catcagtgac     6240

cccacatact acaactcgtg gcggcgacag cagaagggca tctcgagggc acaggcctac     6300

agctacacgg agagcgactc gggtgagcca gaccacacca ccgtcaccaa cagcaccagc     6360

acccagcagg gcagcctctt tcggcccaag gccagtcgga ctccaacgcc ccagaacccc     6420

cctaaccccc caagtcagca gagcaccctc taccgtcccc ccagcagcct ggccccaggc     6480

tcccgggctc ccatagcagg attttcatca tttgtttgac atcagaagag gaaaaagcag     6540

aaagagaaat ggcaccaaac tcctccttca cccctcctct cactgcctgc cagaaaacaa     6600

aaacaccaag aaaccaagtc aacttttcac ctcctgagtt tatttttcca gagattccag     6660

ggccagcaaa gccggcgttc agaaggaggg agaaaaccgt gagaggatgt gtgtggccag     6720

cagctcttca gctttgagat ggtggggttc actgctccct tgggaattac acggagctgg     6780

ggaagtggct gtgtcactgc tatggacacg gagtggggcg ggcatctgga gagagagagg     6840

gagcggaggc taaggactgg aggccgccag gcaggcgtgg ccgagggaag aaaaagcttc     6900

tggatgtcca gccagctgcc cccttccagc ccctccagga cccctggacc cactgccgct     6960

gctctctgca aaaagaatgg gcatcccgga ggccacgcct atcttctctc tctgctcctc     7020

cttccctcca tgcaccatca ctgtggctgg caggcatcgg acagcctcat ccagaccccc     7080

tgccctgtct tggcaacctc tactgcccat ctcccctgct caacttctcc accaagcatt     7140

tggtttattt agaaaaagga agaaaaacaa aaaacaaaaa actaaagggt gagaatttgc     7200

ttagcgcctt ccttgttcct gcatattttt taaaatattg aatccaagga agagagccca     7260

agggtagggg agaaaccccc cacaactgac ccctgcctcc ctgtgctgga attgactttc     7320

ctgagcatgg acaaggaaag gtgaagtctg gggagcagag gtgtaaataa ggcgactggc     7380

cttggcactg tgggatgatt aggtttaacg cattgtgggc aagataagaa tgacactttg     7440

actgttctct ttcttccaat ccaggttcca tccgtcctct ctttaaaggg gtagtcagct     7500

tcccaaggct ggggagtggg gcacagctga gggatctccc tctgggcaga cacgtcactc     7560

tccactggat agatcctcac cacacacaca cacacacaca catctcccat gcacttacaa     7620

ggaacagggt ctagggatcc tctccagaac aaactcatct gggccctcct agccagacag     7680

cacactcact ttcagatctg tgtccctctc actgccaccc ggcagcctcc taagcacaga     7740

ggcacaggag cccagagggg tggcccaagt ccctggtcca gaggctggaa tacccagagt     7800

ttgctcagtc agcctagcac ccagtttaca ggcaaaaagg caaagacacc ctaaccccca     7860

gtaacagctt ccaggctggg ctccgcctgg ccagggcggg gaggggaagg ggcaggtcag     7920

gaagctcagt ccaaagtgga cccagcattt gaattgcacg cccagcaggg gcaggtcaga     7980

tgggaccaag tgacaagaat agctgatggg agggaatgct tttacacaca cacacacaca     8040

cacacacaca catacacata cacaatctgc tccaaggagt gttctgcaaa aagccacatc     8100

cagtggccag gatcttcccg tccacttggt acttacggat gccagggttt agggagaagc     8160

ctttctatct aactccatac attgtccaag gccctctgtg ccctcagcca gccctgtaag     8220

gccagcccaa cacctgcccc accgctgaga tgggtggcag atggcccaca ggggcctgtc     8280

tgattcagcg tgagcccctt cgtggagcag ggctccctct gtgcactgtg tacaggcgct     8340

gctggccctg cccaagagat gatgctctgt tggggtgggt gagcagagtt caaggaagcc     8400

caagtaggag atttgggaaa catgccaagg taagagagag cctggaccac tctcctacag     8460

ccccaagtca gtcactgtgc taatggtgac cgggaaggga agtcagggtc tggggcccaa     8520

agaacgggca cacccagcca tgagtttttc ctgaagcact tgacccctgg gaaatgtgaa     8580

cggggagatg ctggaagatg gctcagcaga caggccagcc cagctccagt gtccaaaaag     8640

cggtttctcc aataaggagg cctgggaagg gaagcacaat cttccccaaa ggagaaccaa     8700

gggctgaggt tctgcccctc caggaagtaa ggtgctctcg gggcctcctt ggacttgtct     8760

gggggctgca gtggagtcag ctggacacct gctccacccc tgccacctcc gcccccaccc     8820

tctgcagcat ctggcatctc catggcagca catctgcagc tgccggcctg tgatcgtgcc     8880

gcacagcttt cttttctttc ctctcatctt tttttttttt ttttttttaa ataacttcat     8940

ccctttccct ctctgctgag catttaacca tttaaggaag ttcccagttt gcattaggga     9000

attatttaag cccagcccag tgagggatta tttgggagga agcaggagtg agtaaaaaca     9060

ttgtgtctgt gtatatattg cacatgaggt caattttcct ttgcctttaa tgaatcacct     9120

ggtgcactaa gatattccac ccccccactc cccacacgct cattcgcacc catgctgaca     9180

cctacgtgta catgcgggat ggtgcccatg cacgcctgtg cttacacaca tgcacacaca     9240

aatatgcaca gaacacacat ctgtatgtgt gttagcaaag agactcctga actccctctg     9300

atggctgaag ccatctctcc cctgtgaggc acaggtggcc tgggttgctt gcacttgggg     9360

cgtggctggg atctattgtc tgagagggtg aggacaccac gcaaatttag acaagcccat     9420

gagatcaggc tgggcccatg gtgaaagtcc cacacttagt caatacccac tcatctggaa     9480

tattgtctcc acagccccag ccacagctgg aagcccaggc ctgcagctgt ggaactctag     9540

attttttcag gacacgtctc tttgcccttg tttacatatc tactggcaca gccgaggctc     9600

ccaaccgtcc tcccagaaac ctggccacat tagaaagggg tggtgggccc tgccctttgt     9660

agaaagagtg ggaccctttc tggcctgtga ttttccgtgc cagtgatgcc agggcccctg     9720

cctgtgggac tccacccaaa gcaggttcac accaggacac acctggcacc tttggcattg     9780

cctccttgtg ccctaagcaa tctcccagtg ttgcacccag gagcccatgc tgggcacacc     9840

agggctttcc ccttcctggc tgcgcctcca gagttgacgt cagctccaca cccacactgc     9900

caagacaaac caaaaagatg ctctgggctc cagaaccacc atcctcctag ggctccagag     9960

agtttgcaaa cccaggctgc ctccccttct gtccatccct caccccccgg cccccaaaac    10020

tcctaccccc aaacctggca ctgccgtgat ttagaggaaa caaggacaca gcgggggctg    10080

cccccacctg gtgcacgctg cctcaaggcc ttctgttgct gcccacgcct ccctgggcag    10140

tgcttctaaa ggtgccagag cctcaccaca gtgccactct ggctgggcag gggcttccct    10200

cagcttccca gagtgcacat ctgaaggtgc ctaccctggg tgaggggctg gtgggcagga    10260

aggtaaaggg gagaccatct gagcagccgc cacccgctcc ccagtgcctc tgtatggccc    10320

tatccaggga cacccatggg catgcgcaca tggcaatcct gaccaccacc tgagcacagg    10380

tgccccctcg ggaccacccc ccttctcttt gtttccatca gaataaccaa aagcatttaa    10440

acgtgttacc tttctccatc catctagact ccagaaacaa aaatcaacac aaatctttat    10500

tttttgattt aaaagatata acaaaaaatt atggggagag tattcattat ggcaggtgtc    10560

tgtctgtaag aaaaaaatat atatctctat gtcatatagc gtgttagcag gtttattttt    10620

taaatgaaag gtaagaaaga aattgatttg aaatatatac cacaagaagt cccgtgtcct    10680

gtcaaactgt cagtatttta taaataaact tttttttttg gaaaaaaaaa aaaaaaaaaa    10740

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa        10796


<210>  2494
<211>  2293
<212>  DNA
<213>  homo sapiens

<400>  2494
atttgggaga gtgctgtgac tcatgctgga ctctaaccca cgagggtttc tcagagtcag       60

cagctggggg atgaagaagt gaaaagtgac tggcaggaaa ttctgcaagc aaggaaaggg      120

aaagagaaat gaactggtgc aggtctgcgg gaagagaatg aggctggatc ctcaaaatca      180

caggaggaag caggcccaga cctcagaggc agaaagagaa agaaaccaga gcttagagtc      240

aggaggagga aaccagaccc cggagccaca aggagagggc tggatccccg gctcagaggg      300

aagagtgtcg ccgcctctgc ctgcgtagcc ccggccatgg ctctgtagcc tcgacccctt      360

tgtgcccccg gcccgtctcc gcgctcacca cgcctgcgct ctccgctccc accttctttc      420

ttcagccgag gccgccgccg cctctccttg ctgcagccat ggagtcttcc actttcgcct      480

tggtgcctgt cttcgcccac ctgagcatcc tccagagcct cgtgccagct gctggtgcag      540

cctctcctgt tgccatcagt gcccagcacc tgtgctacag ccatgtcact cctggcgacc      600

ctggggctgg agctggacag ggccctgctc ccagctagtg ggctgggatg gctcgtagac      660

tatgggaaac tccccccggc ccctgccccc ctggctccct atgaggtcct tgggggagcc      720

ctggagggcg ggcttccagt ggggggagag cccctggcag gtgatggctt ctctgactgg      780

atgactgagc gagttgattt cacagctctc ctccctctgg agcctccctt accccccggc      840

accctccccc aaccttcccc aaccccacct gacctggaag ctatggcctc cctcctcaag      900

aaggagctgg aacagatgga agacttcttc ctagatgccc cgcccctccc accaccctcc      960

ccgccgccac taccaccacc accactacca ccagccccct ccctccccct gtccctcccc     1020

tcctttgacc tcccccagcc ccctgtcttg gatactctgg acttgctggc catctactgc     1080

cgcaacgagg ccgggcagga ggaagtgggg atgccgcctc tgcccccgcc acagcagccc     1140

cctcctcctt ctccacctca accttctcgc ctggccccct acccacatcc tgccaccacc     1200

cgaggggacc gcaagcaaaa gaagagagac cagaacaagt cggcggctct gaggtaccgc     1260

cagcggaagc gggcagaggg tgaggccctg gagggcgagt gccaggggct ggaggcacgg     1320

aatcgcgagc tgaaggaacg ggcagagtcc gtggagcgcg agatccagta cgtcaaggac     1380

ctgctcatcg aggtttacaa ggcccggagc cagaggaccc gtagctgcta gaagggcagg     1440

ggtgtggctt ctgggggctg gtcttcagct ctggcgcctt catccccctg cctctacctt     1500

cattccaaac ccctctcggc cgggtgcagt ggcttatgct tgtaatccca gcactttggg     1560

aggccaaggc aggaggatcg tttgaggcca ggaggtcaat accagcctgg gcaacatagt     1620

aagaccctgt ctctattaaa aaaaaaaaat caacccttct tccccaccaa accacccaac     1680

tcctctctac tcttatcctt ttatcctctg tctctgctta tcacctctct tgcgtatttc     1740

tggatctcct tccctccttt ctcgtccaaa tcatgaaatg tttggcctta gtcaatgtct     1800

atgcccgtca cataacagcc gaggcaccga ggcccacagg gaagcagctg ggagcttgga     1860

aacctggtct cttgaatttc aaacctggtt tcttacaggt ggttgtctgg ggtgggtgga     1920

gtggcgacag gatagagctg aaggactatg caaatgagga agtaagtcag ggcgggcttt     1980

gagaagggga cccatatcct acaggcaaaa agcaggctag gtgaccttgg gacactacgc     2040

taagggaggg aggctaaagg cggccaggtt tgcagtgcgg gaagatgagc aggccagtgg     2100

gaggaggggc agggcagggc tgtagttggt gactgggtgt tcattttagc tctaagaaaa     2160

aaaatcagtg tttcgtgaag gtgttggaga ggggctgtgt ctgggtgagg gatggcgggg     2220

tactgatttt tttgggaggt tatgagcaaa aataaaacga aacatttcct ctggcaaaaa     2280

aaaaaaaaaa aaa                                                        2293


<210>  2495
<211>  8516
<212>  DNA
<213>  homo sapiens

<400>  2495
gagtagctcc agcggccacg ctgaggcgag ggtgacacac catgctcacg gcccctggag       60

accgtcgtgc tggcgagccg tgctccgtag ctccccggtc cgcctcggca gcggtcagag      120

tcgcctacag gagttgagcc gcccgcgcca gaaggttttg gcgaagctct tggagaggcg      180

tcgagcacag tagggcggcg ggggtgcgtt gagcgctcgg gggtcaggca gtcggccggg      240

atcgccgctg gggagcgttt ccgaggcgag gaggaggagg aggagatgct gctcctcttc      300

tccccctccc caggctcctt ctacagctcc ttcagcccac gcccgcagcc gcttgtggga      360

gaagtggtgg tggctctcgg cgcccgcggc ggctgccggc ggcccgcccc gacgccgcgt      420

ccctgcagcc ctcgcccggc gctccagtag caggacccgg tctcgggacc agccggtaat      480

atgcacgtgt cactagctga ggccctggag gttcggggtg gaccacttca ggaggaagaa      540

atatgggctg tattaaatca aagtgctgaa agtctccaag aattattcag aaaagtaagc      600

ctagctgatc ctgctgccct tggcttcatc atttctccat ggtctctgct gttgctgcca      660

tctggtagtg tgtcatttac agatgaaaat atttccaatc aggatcttcg agcattcact      720

gcaccagagg ttcttcaaaa tcagtcacta acttctctct cagatgttga aaagatccac      780

atttattctc ttggaatgac actgtattgg ggggctgatt atgaagtgcc tcagagccaa      840

cctattaagc ttggagatca tctcaacagc atactgcttg gaatgtgtga ggatgttatt      900

tacgctcgag tttctgttcg gactgtgctg gatgcttgca gtgcccacat taggaatagc      960

aattgtgcac cctcattttc ctacgtgaaa cacttggtaa aactggttct gggaaatctt     1020

tctgggacag atcagctttc ctgtaacagt gaacaaaagc ctgatcgaag ccaggctatt     1080

cgagatcgat tgcgaggaaa aggattacca acaggaagaa gctctacttc tgatgtacta     1140

gacatacaaa agcctccact ctctcatcag acctttctta acaaagggct tagtaaatct     1200

atgggatttc tgtccatcaa agatacacaa gatgagaatt atttcaagga cattttatca     1260

gataattctg gacgtgaaga ttctgaaaat acattctccc cttaccagtt caaaactagt     1320

ggcccagaaa aaaaacccat ccctggcatt gatgtgcttt ctaagaagaa gatctgggct     1380

tcatccatgg acttgctttg tacagctgac agagacttct cttcaggaga gactgccaca     1440

tatcgtcgtt gtcaccctga ggcagtaaca gtgcggactt caactactcc tagaaaaaag     1500

gaggcaagat actcagatgg aagtatagcc ttggatatct ttggccctca gaaaatggat     1560

ccaatatatc acactcgaga attgcccacc tcctcagcaa tatcaagtgc tttggaccga     1620

atccgagaga gacaaaagaa acttcaggtt ctgagggaag ccatgaatgt agaagaacca     1680

gttcgaagat acaaaactta tcatggtgat gtctttagta cctccagtga aagtccatct     1740

attatttcct ctgaatcaga tttcagacaa gtgagaagaa gtgaagcctc aaagaggttt     1800

gaatccagca gtggtctccc aggggtagat gaaaccttaa gtcaaggcca gtcacagaga     1860

ccgagcagac aatatgaaac accctttgaa ggcaacttaa ttaatcaaga gatcatgcta     1920

aaacggcaag aggaagaact gatgcagcta caagccaaaa tggcccttag acagtctcgg     1980

ttgagcctat atccaggaga cacaatcaaa gcgtccatgc ttgacatcac cagggatccg     2040

ttaagagaaa ttgccctaga aacagccatg actcaaagaa aactgaggaa tttctttggc     2100

cctgagtttg tgaaaatgac aattgaacca tttatatctt tggatttgcc acggtctatt     2160

cttactaaga aagggaagaa tgaggataac cgaaggaaag taaacataat gcttctgaac     2220

gggcaaagac tggaactgac ctgtgatacc aaaactatat gtaaagatgt gtttgatatg     2280

gttgtggcac atattggctt agtagagcat catttgtttg ctttagctac cctcaaagat     2340

aatgaatatt tctttgttga tcctgactta aaattaacca aagtggcccc agagggatgg     2400

aaagaagaac caaagaaaaa gaccaaagcc actgttaatt ttactttgtt tttcagaatt     2460

aaatttttta tggatgatgt tagtctaata caacatactc tgacgtgtca tcagtattac     2520

cttcagcttc gaaaagatat tttggaggaa aggatgcact gtgatgatga gacttcctta     2580

ttgctggcat ccttggctct ccaggctgag tatggagatt atcaaccaga ggttcatggt     2640

gtgtcttact ttagaatgga gcactatttg cccgccagag tgatggagaa acttgattta     2700

tcctatatca aagaagagtt acccaaattg cataatacct atgtgggagc ttctgaaaaa     2760

gagacagagt tagaattttt aaaggtctgc caaagactga cagaatatgg agttcatttt     2820

caccgagtgc accctgagaa gaagtcacaa acaggaatat tgcttggagt ctgttctaaa     2880

ggtgtccttg tgtttgaagt tcacaatgga gtgcgcacat tggtccttcg ctttccatgg     2940

agggaaacca agaaaatatc tttttctaaa aagaaaatca cattgcaaaa tacatcagat     3000

ggaataaaac atggcttcca gacagacaac agtaagatat gccagtacct gctgcacctc     3060

tgctcttacc agcataagtt ccagctacag atgagagcaa gacagagcaa ccaagatgcc     3120

caagatattg agagagcttc gtttaggagc ctgaatctcc aagcagagtc tgttagagga     3180

tttaatatgg gacgagcaat cagcactggc agtctggcca gcagcaccct caacaaactt     3240

gctgttcgac ctttatcagt tcaagctgag attctgaaga ggctatcctg ctcagagctg     3300

tcgctttacc agccattgca aaacagttca aaagagaaga atgacaaagc ttcatgggag     3360

gaaaagccta gagagatgag taaatcatac catgatctca gtcaggcctc tctctatcca     3420

catcggaaaa atgtcattgt taacatggaa cccccaccac aaaccgttgc agagttggtg     3480

ggaaaacctt ctcaccagat gtcaagatct gatgcagaat ctttggcagg agtgacaaaa     3540

cttaataatt caaagtctgt tgcgagttta aatagaagtc ctgaaaggag gaaacatgaa     3600

tcagactcct catccattga agaccctggg caagcatatg ttctagatgt gctacacaaa     3660

agatggagca tagtatcttc accagaaagg gagatcacct tagtgaacct gaaaaaagat     3720

gcaaagtatg gcttgggatt tcaaattatt ggtggggaga agatgggaag actggaccta     3780

ggcatattta tcagttcagt tgcccctgga ggaccagctg acttggatgg atgcttgaag     3840

ccaggagacc gtttgatatc tgtgaatagt gtgagtctgg agggagtcag ccaccatgct     3900

gcaattgaaa ttttgcaaaa tgcacctgaa gatgtgacac ttgttatctc tcagccaaaa     3960

gaaaagatat ccaaagtgcc ttctactcct gtgcatctca ccaatgagat gaaaaactac     4020

atgaagaaat cttcctacat gcaagacagt gctatagatt cttcttccaa ggatcaccac     4080

tggtcacgtg gtaccctgag gcacatctcg gagaactcct ttgggccatc tgggggcctg     4140

cgggaaggaa gcctgagttc tcaagattcc aggactgaga gtgccagctt gtctcaaagc     4200

caggtcaatg gtttctttgc cagccattta ggtgaccaaa cctggcagga atcacagcat     4260

ggcagccctt ccccatctgt aatatccaaa gccaccgaga aagagacttt cactgatagt     4320

aaccaaagca aaactaaaaa gccaggcatt tctgatgtaa ctgattactc agaccgtgga     4380

gattcagaca tggatgaagc cacttactcc agcagtcagg atcatcaaac accaaaacag     4440

gaatcttcct cttcagtgaa tacatccaac aagatgaatt ttaaaacttt ttcttcatca     4500

cctcctaagc ctggagatat ctttgaggtt gaactggcta aaaatgataa cagcttgggg     4560

ataagtgtca cgggaggtgt gaatacgagt gtcagacatg gtggcattta tgtgaaagct     4620

gttattcccc agggagcagc agagtctgat ggtagaattc acaaaggtga tcgcgtccta     4680

gctgtcaatg gagttagtct agaaggagcc acccataagc aagctgtgga aacactgaga     4740

aatacaggac aggtggttca tctgttatta gaaaagggac aatctccaac atctaaagaa     4800

catgtcccgg taaccccaca gtgtaccctt tcagatcaga atgcccaagg tcaaggccca     4860

gaaaaagtga agaaaacaac tcaggtcaaa gactacagct ttgtcactga agaaaataca     4920

tttgaggtaa aattatttaa aaatagctca ggtctaggat tcagtttttc tcgagaagat     4980

aatcttatac cggagcaaat taatgccagc atagtaaggg ttaaaaagct ctttcctgga     5040

cagccagcag cagaaagtgg aaaaattgat gtaggagatg ttatcttgaa agtgaatgga     5100

gcctctttga aaggactatc tcagcaggaa gtcatatctg ctctcagggg aactgctcca     5160

gaagtattct tgcttctctg cagacctcca cctggtgtgc taccggaaat tgatactgcg     5220

cttttgaccc cacttcagtc tccagcacaa gtacttccaa acagcagtaa agactcttct     5280

cagccatcat gtgtggagca aagcaccagc tcagatgaaa atgaaatgtc agacaaaagc     5340

aaaaaacagt gcaagtcccc atccagaaga gacagttaca gtgacagcag tgggagtgga     5400

gaagatgact tagtgacagc tccagcaaac atatcaaatt cgacctggag ttcagctttg     5460

catcagactc taagcaacat ggtatcacag gcacagagtc atcatgaagc acccaagagt     5520

caagaagata ccatttgtac catgttttac tatcctcaga aaattcccaa taaaccagag     5580

tttgaggaca gtaatccttc ccctctacca ccggatatgg ctcctgggca gagttatcaa     5640

ccccaatcag aatctgcttc ctctagttcg atggataagt atcatataca tcacatttct     5700

gaaccaacta gacaagaaaa ctggacacct ttgaaaaatg acttggaaaa tcaccttgaa     5760

gactttgaac tggaagtaga actcctcatt accctaatta aatcagaaaa aggaagcctg     5820

ggttttacag taaccaaagg caatcagaga attggttgtt atgttcatga tgtcatacag     5880

gatccagcca aaagtgatgg aaggctaaaa cctggggacc ggctcataaa ggttaatgat     5940

acagatgtta ctaatatgac tcatacagat gcagttaatc tgctccgggc tgcatccaaa     6000

acagtcagat tagttattgg acgagttcta gaattaccca gaataccaat gttgcctcat     6060

ttgctaccgg acataacact aacgtgcaac aaagaggagt tgggtttttc cttatgtgga     6120

ggtcatgaca gcctttatca agtggtatat attagtgata ttaatccaag gtccgtcgca     6180

gccattgagg gtaatctcca gctattagat gtcatccatt atgtgaacgg agtcagcaca     6240

caaggaatga ccttggagga agttaacaga gcattagaca tgtcacttcc ttcattggta     6300

ttgaaagcaa caagaaatga tcttccagtg gtccccagct caaagaggtc tgctgtttca     6360

gctccaaagt caaccaaagg caatggttcc tacagtgtgg ggtcttgcag ccagcctgcc     6420

ctcactccta atgattcatt ctccacggtt gctggggaag aaataaatga aatatcgtac     6480

cccaaaggaa aatgttctac ttatcagata aagggatcac caaacttgac tctgcccaaa     6540

gaatcttata tacaagaaga tgacatttat gatgattccc aagaagctga agttatccag     6600

tctctgctgg atgttgtgga tgaggaagcc cagaatcttt taaacgaaaa taatgcagca     6660

ggatactcct gtggtccagg tacattaaag atgaatggga agttatcaga agagagaaca     6720

gaagatacag actgcgatgg ttcaccttta cctgagtatt ttactgaggc caccaaaatg     6780

aatggctgtg aagaatattg tgaagaaaaa gtaaaaagtg aaagcttaat tcagaagcca     6840

caagaaaaga agactgatga tgatgaaata acatggggaa atgatgagtt gccaatagag     6900

agaacaaacc atgaagattc tgataaagat cattcctttc tgacaaacga tgagctcgct     6960

gtactccctg tcgtcaaagt gcttccctct ggtaaataca cgggtgccaa cttaaaatca     7020

gtcattcgag tcctgcgggg tttgctagat caaggaattc cttctaagga gctggagaat     7080

cttcaagaat taaaaccttt ggatcagtgt ctaattgggc aaactaagga aaacagaagg     7140

aagaacagat ataaaaatat acttccctat gatgctacaa gagtgcctct tggagatgaa     7200

ggtggctata tcaatgccag cttcattaag ataccagttg ggaaagaaga gttcgtttac     7260

attgcctgcc aaggaccact gcctacaact gttggagact tctggcagat gatttgggag     7320

caaaaatcca cagtgatagc catgatgact caagaagtag aaggagaaaa aatcaaatgc     7380

cagcgctatt ggcccaacat cctaggcaaa acaacaatgg tcagcaacag acttcgactg     7440

gctcttgtga gaatgcagca gctgaagggc tttgtggtga gggcaatgac ccttgaagat     7500

attcagacca gagaggtgcg ccatatttct catctgaatt tcactgcctg gccagaccat     7560

gatacacctt ctcaaccaga tgatctgctt acttttatct cctacatgag acacatccac     7620

agatcaggcc caatcattac gcactgcagt gctggcattg gacgttcagg gaccctgatt     7680

tgcatagatg tggttctggg attaatcagt caggatcttg attttgacat ctctgatttg     7740

gtgcgctgca tgagactaca aagacacgga atggttcaga cagaggatca atatattttc     7800

tgctatcaag tcatccttta tgtcctgaca cgtcttcaag cagaagaaga gcaaaaacag     7860

cagcctcagc ttctgaagtg acatgaaaag agcctctgga tgcatttcca tttctctcct     7920

taacctccag cagactcctg ctctctatcc aaaataaaga tcacagagca gcaagttcat     7980

acaacatgca tgttctcctc tatcttagag gggtattctt cttgaaaata aaaaatattg     8040

aaatgctgta tttttacagc tactttaacc tatgataatt atttacaaaa ttttaacact     8100

aaccaaacaa tgcagatctt agggatgatt aaaggcagca tttgatgata gcagacattg     8160

ttacaaggac atggtgagtc tatttttaat gcaccaatct tgtttatagc aaaaatgttt     8220

tccaatattt taataaagta gttattttat aggggatact tgaaaccagt atttaagctt     8280

taaatgacag taatattggc atagaaaaaa gtagcaaatg tttactgtat caatttctaa     8340

tgtttactat atagaatttc ctgtaatata tttatatact ttttcatgaa aatggagtta     8400

tcagttatct gtttgttact gcatcatctg tttgtaatca ttatctcact ttgtaaataa     8460

aaacacacct taaaacatga acaagccaaa actgtgtgca gacaaaaaaa aaaaaa         8516


<210>  2496
<211>  1447
<212>  DNA
<213>  homo sapiens

<400>  2496
gggtccaggc tgcggcgcgt ggggagcggg cggagcgggg gcgggggccg agcgcggggc       60

acccgggggc ctcctgtata ggcgggcacc atgggctcct gctccggccg ctgcgcgctc      120

gtcgtcctct gcgcttttca gctggtcgcc gccctggaga ggcaggtgtt tgacttcctg      180

ggctaccagt gggcgcccat cctggccaac tttgtccaca tcatcatcgt catcctggga      240

ctcttcggca ccatccagta ccggctgcgc tatgtcatgg tgtacacgct gtgggcagcc      300

gtctgggtca cctggaacgt cttcatcatc tgcttctacc tggaagtcgg tggcctctta      360

aaggacagcg agctactgac cttcagcctc tcccggcatc gctcctggtg gcgtgagcgc      420

tggccaggct gtctgcatga ggaggtgcca gcagtgggcc tcggggcccc ccatggccag      480

gccctggtgt caggtgctgg ctgtgccctg gagcccagct atgtggaggc cctacacagt      540

tgcctgcaga tcctgatcgc gcttctgggc tttgtctgtg gctgccaggt ggtcagcgtg      600

tttacggagg aagaggacag ctttgatttc attggtggat ttgatccatt tcctctctac      660

catgtcaatg aaaagccatc cagtctcttg tccaagcagg tgtacttgcc tgcgtaagtg      720

aggaaacagc tgatcctgct cctgtggcct ccagcctcag cgaccgacca gtgacaatga      780

caggagctcc caggccttgg gacgcgcccc cacccagcac cccccaggcg gccggcagca      840

cctgccctgg gttctaagta ctggacacca gccagggcgg cagggcagtg ccacggctgg      900

ctgcagcgtc aagagagttt gtaatttcct ttctcttaaa aaaaaaaaag aaaagaaaac      960

atacaaaaga aaaggcaaaa ccccacatgc ccacctcctc tggcaacatg ggggtcacag     1020

ctctgccccc aggctgtcgt ctcgtcgagg agcccctccc tcaggtgccc acctggggct     1080

gctggaccct cgggctgcaa gcactgctgc tgggatgcag cctccccagg aagtcaatgt     1140

gaggcccgag acccctcaag cggtgagggc ccctgttgaa catggagggt tcctaacccc     1200

aaactcgtgc cagaagaacc cccaccccac ccaggagctg aggctgatgg agccctaggg     1260

tgggggctgg gcttgaccag gaacagcaga gccaggcccc aaggcatagg gcagggcaca     1320

tggtggtgac gagcaggcag tactcttgta aagggggctc ttgggcaaac agtcccaaag     1380

gctcccccag gtatcatcaa gttggtaaat aaacaggaac atggccctca aaaaaaaaaa     1440

aaaaaaa                                                               1447


<210>  2497
<211>  1447
<212>  DNA
<213>  homo sapiens

<400>  2497
gggtccaggc tgcggcgcgt ggggagcggg cggagcgggg gcgggggccg agcgcggggc       60

acccgggggc ctcctgtata ggcgggcacc atgggctcct gctccggccg ctgcgcgctc      120

gtcgtcctct gcgcttttca gctggtcgcc gccctggaga ggcaggtgtt tgacttcctg      180

ggctaccagt gggcgcccat cctggccaac tttgtccaca tcatcatcgt catcctggga      240

ctcttcggca ccatccagta ccggctgcgc tatgtcatgg tgtacacgct gtgggcagcc      300

gtctgggtca cctggaacgt cttcatcatc tgcttctacc tggaagtcgg tggcctctta      360

aaggacagcg agctactgac cttcagcctc tcccggcatc gctcctggtg gcgtgagcgc      420

tggccaggct gtctgcatga ggaggtgcca gcagtgggcc tcggggcccc ccatggccag      480

gccctggtgt caggtgctgg ctgtgccctg gagcccagct atgtggaggc cctacacagt      540

tgcctgcaga tcctgatcgc gcttctgggc tttgtctgtg gctgccaggt ggtcagcgtg      600

tttacggagg aagaggacag ctttgatttc attggtggat ttgatccatt tcctctctac      660

catgtcaatg aaaagccatc cagtctcttg tccaagcagg tgtacttgcc tgcgtaagtg      720

aggaaacagc tgatcctgct cctgtggcct ccagcctcag cgaccgacca gtgacaatga      780

caggagctcc caggccttgg gacgcgcccc cacccagcac cccccaggcg gccggcagca      840

cctgccctgg gttctaagta ctggacacca gccagggcgg cagggcagtg ccacggctgg      900

ctgcagcgtc aagagagttt gtaatttcct ttctcttaaa aaaaaaaaag aaaagaaaac      960

atacaaaaga aaaggcaaaa ccccacatgc ccacctcctc tggcaacatg ggggtcacag     1020

ctctgccccc aggctgtcgt ctcgtcgagg agcccctccc tcaggtgccc acctggggct     1080

gctggaccct cgggctgcaa gcactgctgc tgggatgcag cctccccagg aagtcaatgt     1140

gaggcccgag acccctcaag cggtgagggc ccctgttgaa catggagggt tcctaacccc     1200

aaactcgtgc cagaagaacc cccaccccac ccaggagctg aggctgatgg agccctaggg     1260

tgggggctgg gcttgaccag gaacagcaga gccaggcccc aaggcatagg gcagggcaca     1320

tggtggtgac gagcaggcag tactcttgta aagggggctc ttgggcaaac agtcccaaag     1380

gctcccccag gtatcatcaa gttggtaaat aaacaggaac atggccctca aaaaaaaaaa     1440

aaaaaaa                                                               1447


<210>  2498
<211>  2822
<212>  DNA
<213>  homo sapiens

<400>  2498
ggcgcggtac aggagcagca ctgccggcgg gggcgggtgc cagggacttg gaggtggagg       60

ggacgcggcg gtactctggc gtcttccgac ttcgactcct taccttaaaa gatgctggag      120

tcatatgtaa ctccaatttt aatgagctat gtgaatcgct acatcaagaa cttaaagccg      180

tcggatctac agctttcact atggggtgga gacgtggtac tcagcaagct cgagttaaag      240

ttggatgtgc tggaacagga actgaaatta ccattcactt ttttaagtgg acatattcat      300

gaattgagga ttcatgtacc atggacaaaa ctgggttcag aaccagtggt aattaccatc      360

aatactatgg aatgcatttt gaaacttaag gatgggatac aggatgacca tgaaagctgt      420

ggttctaatt ctaccaaccg tagtactgct gagagcacaa aatcatcaat caaaccgcgg      480

agaatgcagc aggctgctcc tacagatcct gacttaccac caggttatgt gcagagtctg      540

attagacgag ttgtaaataa tgtaaacatt gtgataaata atctcatact aaaatatgtt      600

gaagatgata tcgtcctttc cgtcaatatc acttctgcag aatgttatac agtaggtgaa      660

ttatgggatc gtgcattcat ggatatttct gcaactgatt tggtgctgag aaaggttatc      720

aatttttctg actgtacagt ttgtcttgat aaacggaatg ccagtggtaa aatagaattt      780

taccaggatc ctttattata caaatgttcc ttcagaactc gtcttcattt tacatatgaa      840

aacctaaatt ccaagatgcc atctgttatt aaaattcata ctttagtgga aagtttgaaa      900

ctttctatca cagatcaaca actgcctatg tttattcgta taatgcaact tggaattgct      960

ctttactatg gagaaatagg caattttaaa gaaggcgaaa tagaggacct tacttgtcat     1020

aataaagata tgctaggaaa cattacaggt tctgaagatg aaacaagaat agatatgcaa     1080

tatcctgctc agcataaagg tcaagagtta tattcacagc aagatgagga gcagccacag     1140

ggatgggtgt catgggcctg gtcctttgtg cctgcaattg tgagttatga cgatggcgag     1200

gaagactttg ttgggaacga tcctgcatca accatgcatc aacaaaaagc acagactttg     1260

aaggatccta ttgtttctat aggattttat tgcacaaagg caacggtgac tttcaaactc     1320

acagaaatgc aagttgagag tagttattac agtccacaga aagtaaaatc taaagaagta     1380

ttgtgttggg aacaagaagg aactacagtt gaggccctta tgatgggaga acctttcttt     1440

gattgccaga ttgggtttgt tggttgcaga gccatgtgcc ttaaaggaat tatgggtgtt     1500

aaagattttg aagagaatat gaatagaagt gaaactgaag cctgtttctt catttgtggt     1560

gacaatttga gtacgaaagg tttcacatac cttacaaatt cattgtttga ttaccgaagc     1620

ccagaaaata atggtactcg cgcagaattt atcttggatt caactcatca taaggagaca     1680

tacactgaga tagctggaat gcaacggttt ggggcttttt atatggatta cctgtataca     1740

atggagaaca ctagtggcaa aggttccaca aatcaacaag acttttcttc agggaaaagt     1800

gaagatttgg gaacagttca ggagaagtcc accaaaagcc ttgttatagg tcctcttgat     1860

tttcgtttgg atagcagtgc ggtgcatagg attttgaaaa tgattgtgtg tgccttggaa     1920

catgaatatg aaccatatag caggctaaaa tcagatatta aggatgaaaa tgaaacaata     1980

ctgaatcctg aagaggtggc tcttctggag gaatatattc ctactcgaca tacaagtgtt     2040

actctcctca aatgtacctg cacaatttcc atggctgaat tcaacttgct ggaccattta     2100

ctacctgtca ttatgggaga aaagaactca agtaacttca tgaatactac aaacttccag     2160

tctcttcggc ctttgccatc cattcgaata ttggtggata aaattaatct ggaacattca     2220

gtgccaatgt atgctgaaca gttggtgcat gtggtcagca gccttactca accttctgat     2280

aacctgcttc attattgtta tgtacactgc tatcttaaga tatttggttt ccaggcagga     2340

ctgacgtctt tggattgcag tggatcttac tgcttacctg taccagttat tccctctttc     2400

agcactgctc tttatgggaa acttctgaaa ctccccacat gctggaccaa aagatctcag     2460

attgctataa ctgaaggtat atttgaactt ccaaatctca caattcaagc tacaagagca     2520

cagacacttc tcttgcaagc aatatatcaa agttggtctc atcttggaaa tgtcagctct     2580

tccgcagtga ttgaagcttt gataaatgaa atcttcctaa gtatagagat tgggtcttgc     2640

tatgttgccc aggttgatct tgaactcctg gcctcaaatg atcctcccac ctcaacctcc     2700

tgaagtgccg ggattggagg cccaagccac tgtgcctggc cctttataaa ttatgttata     2760

atttcatgta atacataatt gtatagtcaa aatggctcac atattaaata ttctttatac     2820

aa                                                                    2822


<210>  2499
<211>  2512
<212>  DNA
<213>  homo sapiens

<400>  2499
aattggtacc aggagagccc agaagccaca cacgcatctc tgcctctttg ctctggctct       60

cccaccctct tcccgtcttt ctctgcttcc ttgtcactgt tactccagga gacgttcact      120

tttcaccaac ctttctccaa gcatctccaa gccactgact atatatattt tgctacaaga      180

gacctagaag aggaaaaaag gcacgagact tttcaacaca tcgtttaaaa aaatcatcaa      240

cgaatttctt gcaatgtttg agaacaatta aaaggaaaaa gcgtttttta aaaaatctat      300

caactaagtg aacaatcatt catatcgtct acatcctgag atattattgt ccctcgctgc      360

ggacaccagc gagatgacag ctgctttttc atttttgaat gtaataaata tttgctgctt      420

ttaatatttt ccggaatctc ccctcgctat tccttggaat tttaactcta aagattggag      480

aacagattat caaaaaggct tttgcaagcc tccaaaatga tgctgagtcc ggaccaagca      540

gcagattcgg accatcccag ctcggcgcac tcggatccgg agtccctggg cggcacggac      600

accaaggtgc tcggcagcgt gtcggacctg gagccggtgg aggaggccga gggcgacggc      660

aagggcggca gccgagccgc gctctacccg cacccgcagc agctgagccg cgaggagaag      720

cgccgccgcc ggcgcgccac ggccaagtac cgctcggccc acgccacccg cgagcgcatc      780

cgcgtggaag ccttcaactt ggccttcgcc gagctccgca aattgctgcc cacgctgccc      840

ccggacaaga agctctccaa gatcgagatc ctgcgcctgg ccatctgcta catctcctat      900

ctcaaccacg tcctggacgt gtagggcggg gtgcgccgcg gggggccgcc tgtcccggcg      960

tccgcgaaac gctacggatc cggacgggcg ccgtcgctcg ggtggcggag gctgcggtgg     1020

cccagcgaga cggccgcctc gagagacggc cggggaagaa gctcgctacc tgttctctct     1080

ggtcagcagg gcgacgaggg aaggtttccg acgcaggcag gtggggttgt ctggcgagcc     1140

cgggggctcg caggggggat tttccaggcc aggagaacct cgtggagaca cccgagatga     1200

gccacttctg gggctcccca agggttgtgg ttttaaccca ctggagactt tgagttctcc     1260

tacattcatc cgccacaaat cttaatgtgt tgaaagaatg agggcagaag ttcagagtat     1320

gcaggctcat aactttaggc tatctggaat ttttctaatg gacaaatcac caaacactgg     1380

gaaggaggag agaggaggga tctctcccat agagatggaa ggcacagaaa ggtgcgactg     1440

gaaactttcc tttctgttgt gaaaataaag attatattag aatccaaata aaccctgaat     1500

atttagtaag tttaaaaaga caaattgaga acaagtagac acactgtggg aggatctgag     1560

cttggtgata ttttatcccc aagatatgac accaaggtag acaggaaaat ccatatttaa     1620

atggaaactt taatatctga ttacttttgc aggcgaagtg cccctttata tatccaaaaa     1680

catctatttg tgaccttaaa catgtggacc cataggtgca gttagaaaaa gacaacctat     1740

ttttatttat gttagaagga gtagagtatt tttttcaaga catttatttt tcagagtggt     1800

gatactttta ctttggatac tctgtgccaa tttatttata gtcaagtgtt tacacttttt     1860

cctgtggaat aattatgtct aactttttac gtgtttgttg agattatact gtggtctttc     1920

tttctgctct aattatattg cacttgtata acaaatttcc cacttctccc tgtttctaaa     1980

catattttat atattaagat gtttgttctt gaaaggttct tttgttgtga gatcagcaac     2040

actagcactt cactattata gttttttaaa aagtgtatta ttcttatctg tagttatgtc     2100

tgagaagtcc tttacaagct gtttataagg agagtagctt ctttgtgtgt gtgatgtttg     2160

tgcgtgtgat gaatttagca aattaagtta ttttcctaaa aaaaaaagaa aaaaagaatt     2220

cagaactact ttcctctgtg acaccaaaaa gaaaagtcta taacctgaaa atgtttcatg     2280

ttctctgctg tgaaactctt aaaacaagga gtgtatttta gagacaaggg aaaaaaacca     2340

catctgctat ccaaagattt tagtcttttt cagggttttt ttgtgtctct gttgctttat     2400

ataatgcaat attttgtagt gaaaatagat ataatctggt ttctatctga cgagtttttc     2460

atatctcatg aatggtgcgc tgttttgcat ataaataaag gtatcaaata aa             2512


<210>  2500
<211>  7011
<212>  DNA
<213>  homo sapiens

<400>  2500
agttacatca gcctgggcag atgtctaagg atatgagacc gggggaagaa aaagttagaa       60

tctgtagcag aaggacgaag cttgccacct gcctactggg ctgagctttt aatgtgattt      120

acatttctaa gctctatgta ggtgccctgg aaatggtggt cttcattaat gcaaagatta      180

agtctttaat taaacttttt aagaagaaaa cggtttccaa cctagatgag gaaagccgat      240

ggacagtcca ctacactgcc ccgtggcacc agcaggagaa tgtgttcctt cccaccacaa      300

gacccccctg tgttgaggac ctgcaccgcc aagccaagct caacctcaaa tcagtactga      360

gggaatgcga taagttgcgg catgatggct accgcagttc tcagtactac tctcagggac      420

ccacctttgc ggccaacgcc agcccattct gtgatgatta ccaagatgaa gatgaagaaa      480

cagatcaaaa gtgttctctg tcttcatcag aagaagaaag atttatttcc atcaggagac      540

ctaaaacacc agcctcaagt gacttctccg accttaatac tcagacgaac tggaccaagt      600

cgcttccact gccaacacca gaagagaaga tgcgacagca agcccaaaca gtccaggctg      660

acgtggtgcc tattaacata actggggaga atttcgatcg ccaggccagc cttcggcggt      720

ctctaattta cacagacact ctggtaagac gaccgaagaa agtcaaaagg agaaagacta      780

ttacaggagt ccctgacaac atacagaagg agctagcatc aggcactggc caagatgatg      840

ctgatggcca ctcagtgtac acccctgatc actactctac actaggaagg ttcaatagct      900

gtcggtctgc tgggcagcgc tcagaaacca gggactccag ctgtcagacg gaggatgtga      960

aggtcgtacc accttccatg aggagaatca gggcacagaa ggggcaaggc attgctgccc     1020

agatgggcca cttctcaggt tcctctggca acatgtctgt gctgagcgat tctgcaggga     1080

tcgtattccc ttcccgcctt gacagtgatg ctggcttcca tagtcttccg cgttctggag     1140

caagggcaaa cattcagtcc cttgagccga ggctgggtgc cctcggccct gcaggagaca     1200

tgaatggcac tttcctctac cagagaggtc acccacaagc agatgaaaac ttaggccatt     1260

taggaggtgc ctcagggact ggaacacttt tgagacccaa atcccaggag ttgagacact     1320

tcgagagtga aaatataatg agcccagcgt gtgtggtttc tcctcatgca acctactcca     1380

ccagcatcat cccaaatgcc acactgtctt cctcttccga ggtcatcgct attcccactg     1440

ctcagagtgc gggacagcgg gaaagtaaaa gttctggctc atcacatgca aggataaaat     1500

ccagagacca cctcatctcc aggcatgctg tgaaaggtga tcctcagtct cccggtcgcc     1560

actggaatga gggccatgcc accattcttt cacaggactt agaccctcat tcccctggtg     1620

aacccgcact gttgtccctc tgtgactcag ccgtccctct aaatgctcca gcaaataggg     1680

agaatgggtc ccaagctatg ccgtataatt gtagaaacaa cctggccttc ccagcccacc     1740

cccaagatgt ggatggcaag agtgaatcta gttattcagg gggcggaggg cacagcagct     1800

cggagccctg ggaatacaaa tcctcaggta atggaagggc atcccccctg aagccgcatt     1860

tagcaactcc tggctattcc actcccacaa gtaacatgag cagctgcagt ttggaccaaa     1920

cgtccaacaa agaggatgct gggtcgctgt attctgagga ccacgatggc tactgtgcat     1980

ctgtgcacac tgactctgga catggatctg ggaatctgtg caatagcagt gatggctttg     2040

ggaaccccag gcacagcgtg atcaatgttt ttgttggaag agctcagaaa aaccaagggg     2100

accggtccaa ttaccaggat aaatccctat caagaaacat ctctttgaag aaagcaaaga     2160

agcctcccct gccaccctcc cggacagact ccctccgcag gattcccaag aagagcagcc     2220

agtgcaacgg gcaggtgctc aacgagagcc tgatcgccac actccagcac tcgctgcagc     2280

tgagcctccc aggcaagagt ggcagctcgc cctcccagag cccctgcagt gacttggaag     2340

agccctggct gccccgctcc cggagccaga gcacagttag tgctggcagc agcatgactt     2400

ccgccaccac ccccaatgtc tactccctgt gcggggccac gccatcgcag agtgacacaa     2460

gcagcgtcaa gtcagagtac acggacccct ggggttatta cattgactac acgggcatgc     2520

aggaagatcc ggggaacccg gcagggggct gttcaaccag cagtggggtg cccactggga     2580

acgggccagt ccgccatgtc caagaagggt ccagagccac aatgccccaa gtgcccggtg     2640

gttcagtcaa accaaagatc atgtcaccag agaagtcaca cagagtcatt tctccatcca     2700

gtgggtattc cagccagtcg aatacaccca cagcactcac ccctgtgcct gtgtttttaa     2760

aatcagtgtc accagcaaac gggaagggga agcccaagcc caaggtacca gaaaggaagt     2820

cctctctgat atcttcagta tccatttcct catcgtccac ttctctttct tctagtactt     2880

ctactgaagg aagtggcact atgaagaagc tggatccagc cgtgggctct cccccggctc     2940

ctcctcctcc tcctgttccc tctcctccat tcccttgtcc tgcagacagg tctcctttcc     3000

ttcctccccc acctcctgtc acagattgct cccagggctc tcctctgcct cactctcctg     3060

tgttcccccc tccgccgcca gaagctctca ttcctttctg ctccccacct gattggtgcc     3120

tttctcctcc ccgccctgca ctgagcccca ttcttccaga ttcacctgtg tccttgccat     3180

tgcccccacc tctcttacct tcctcggaac ccccacctgc cccacctctt gaccccaaat     3240

tcatgaaaga caccaggccg cctttcacaa attctggcca gccagaatcc tcccggggat     3300

ccttgaggcc gccttctacc aaggaggaga ccagcaggcc ccccatgccc ctgataacca     3360

cggaagcatt gcagatggtg cagttgaggc ccgtgagaaa gaactcaggc gctgaggcgg     3420

cacagttgtc tgaacgaaca gctcaggaac aacgaactcc agttgctcca cagtaccact     3480

taaagccatc tgctttcctg aaatcccgaa atagcacaaa tgaaatggag agtgaaagcc     3540

agcctgcctc tgtgacaagc tcgcttccga cgcctgccaa gagctcgagt cagggtgacc     3600

atggcagtgc ggctgagcgt ggtggccctg tgagccgcag ccctggagct ccaagcgctg     3660

gggaggcaga ggctcggccc agccccagca ccaccccact cccagactct tcacccagca     3720

ggaagccacc ccccatttcc aagaagccca aactgttcct ggtggtacca cctccgcaga     3780

aagattttgc agtggagccc gcagagaacg tgagcgaagc cctccgagct gtgcccagcc     3840

ccacgacggg agaggagggc tctgtgcaca gcagggaggc aaaagagagt tctgcagccc     3900

aagctggctc tcatgccacg caccctggca cctcggttct tgagggagga gctgcaggat     3960

ccatgtctcc cagcagagtg gaagccaatg tccccatggt tcagcctgat gtctcaccag     4020

cccccaagca ggaggagcca gccgagaaca gtgcggatac tgggggcgat ggggagagct     4080

gcctatctca acaggacgga gcagctgggg tgccggagac caacgcagcc ggttcatcct     4140

cagaggcctg tgacttcctc aaggaagacg ggaatgatga ggtaatgacc cccagtcgac     4200

ccaggaccac agaagacctt tttgcagcta ttcacagatc caaaaggaaa gtcctcggcc     4260

gtagagattc agatgatgac cactcccgaa accattctcc ctccccgccc gtgacaccca     4320

ccggcgctgc cccaagcctg gcctctccaa agcaagtggg gtcgattcag agaagcatcc     4380

gaaagagcag caccagcagt gacaacttca aagctctgct gctgaaaaag ggcagtcgtt     4440

cagacaccag cgcccgcatg tctgcagcag agatgctcaa gaacacagac cctagattcc     4500

agaggtcgag gtcagagcct tccccagatg cccccgagag cccgtcaagc tgctccccaa     4560

gcaagaacag aagggcgcag gaggagtggg ccaagaacga aggcttgatg cctcggagtc     4620

tgtccttttc cggccccagg tacggccgca gccgaacgcc gccttctgcc gccagcagca     4680

ggtacagcat gcggaaccgg atccagagca gccccatgac cgtcatctcg gagggagaag     4740

gggaagccgt ggagcctgtg gacagcatag cccgcggggc tctgggcgct gcggagggat     4800

gttccctgga cggactggcg agggaggaga tggacgaggg cggcctgctc tgtggggagg     4860

ggcctgccgc ctccctgcag ccccaggccc ccggccctgt ggatgggaca gccagtgcag     4920

agggcagaga gccctcccca cagtgtggcg gttctctgag cgaggagagt tagggccaag     4980

aacgtaactc tcccaggtga cacgggggga gacgagcaat gcagcactct aggaagcctg     5040

ctaggcgccc ttccctggct cacccgggga gcccactctg cttctgtgct gtgggccccg     5100

gggttgccag ccctgcagtg tgagtgaacg gttatttagg actcacctgg cacttgccct     5160

gtggcttaag aacaagtaga agcttaaact tctgaaagtg cttcccgggg aagatttttt     5220

tttttttttt ttttttttgc taaatgctgg gtgtgtatgt gtgcattttc cacacttttt     5280

aatttttaaa aaatacacat atacacaaac aacatgtaca gaaatagaag aaagcaagcc     5340

agacttaagc ttggtagagt aacggagtcc tctggtctag gcggtaattg ctttcagaga     5400

attacgttta tagaaatcag cgagttttgt aagaaaggag aagatgttac ttcaagaaag     5460

aggcagtaga gttgctggtt cttaatgcac agaacacaca gatatatgca cacgtgtgct     5520

gctgaggtga ggcaggtctg gtgagcacgg agaggctggg aaggggctaa gtgactaatt     5580

ggttcaggta cttttttctg ggggaggtag actttgcttc ttttttgtaa aaatgacaaa     5640

cgtagaagtg gcaatgctgt aacctggtgc ctgctgctgt gcagccacat acacacaatt     5700

gtagcctgat ttttagaagt gtgggtaatt ttttaatgaa tttcctcctt gagtagcagc     5760

tgaggtcatt gacaactgaa gtgatggtgt ggacatagag agaggggaag ggttggaaag     5820

gagtaagtga tacactgctg gaatttgttt cctgcctatg aaataaaatt atttttcaga     5880

attaaatttg aaaacttgca ctacagaact atgggtggag cttttccttt tacaacagtt     5940

tttttttttt ttttttttta accagagttt aaacttccat taggcaattt cctgtcactt     6000

gaaatgtcaa catttgctaa cttttggata tccttttggt tacaccaaag aaaaagttat     6060

ggctattttt ttttccttga actgcctaca gtatcatgtc ctaattcaga aagatttatc     6120

aaaatctatt atatattatc ttactttgaa gaaaatgctg aatagctctt gttagtcaaa     6180

taaactgata aaaattggta gggcctggct atcaattagc cctgggaaat gaatttttag     6240

attaaaaagg tttttttgca tcatttggtt tgtgcatttt tatatttgtt tataaataat     6300

tgagttgcta attacttcta atcttctcca atcagatttt caacaatttt agacatggga     6360

cacacgtgtg tgaagtcttt attttaatgt aataatctca ttacccccac ccttactccc     6420

ttaacttcca tgtacttaga ctcctttatt tgttaaataa actagagtat tgtcttcttc     6480

attagaagga cctaggatga caatgcggag agtcttggtc tgaatctagt gcgactacca     6540

cctgccagct tttggggggt atggaaatac tatctaaaag ttggactgca tgggtcaaat     6600

cattatgaga cttataaact aaaactttag atacccatat agaaatgtct ttgaggcaaa     6660

aacaaaccta aagaatgaag gctctttccc ttctctgaaa aaaacaaaac actgctcttc     6720

acacaaccgg aagtcaagac cagagatttg gagcaattgt ctactaattt ggcacaaaga     6780

tcgtttcttt agaaaagtgg cattggcttt tgaatatgaa atcttctcat agctgcctaa     6840

aaaagactag aatgtatatg gatatcagaa acctttaata atacataatt tatgcaaaga     6900

taagataaag caacataaca ctaattataa aactattttt aaatccccat ttttaatgaa     6960

aaatatacat ttgtatttaa tttcctttga ataaaacaat tgtaaagtaa a              7011


<210>  2501
<211>  7491
<212>  DNA
<213>  homo sapiens

<400>  2501
acagacggga aggagagcaa gtgggcggtt tatgattctg ccctgtgctg gggcgagtga       60

gctgagctct ttgatttctc ccaagtaacc gtgtgggtga actgtaaact gggtgcctgg      120

cttgaccctg actctttttc tctagggtga ggagttactt caccagggca gctggctttc      180

tgccctggtg gggaaagatg cccaggagag gagtaggatt acaatttggg atgctaggga      240

cacgccaaag agtcggggtg ccttggcttt gtgttttgca aagtcctgac aagtactcct      300

gaaatgaaca cgctgcttca ttttttaaat tatactttta tttgtttatt attttttggc      360

cgtggatatc gcggatctag aaacggagtc cacaatgtgg ctagggtaaa acatttttct      420

tttctttctt aacccctcct tttccctttc tttttaattg ggtgacacag aagccgtctt      480

tttggataat gcggtgcctg actgtcagcg ttgtctaaga gggaaacagc aggctcgtgg      540

agaggacctg ggccaacgca aaaaacccag cgttttgttt gctgggctgt tctttgtctc      600

tagttgattt tgaaaagaag atgaaaaagg aaggctcttc aggttccttc agactccagc      660

cgaatacagg ttctctctca cgtgctgtaa gttggataaa tttctcctcc ttgtccaggc      720

agacaaagag gctgtttcgc agtgatggag agctctcggt ttgtgggcag caggtggaag      780

tggatgacga aaactggata tacagagccc agcccagaaa agcggtttcc aacctagatg      840

aggaaagccg atggacagtc cactacactg ccccgtggca ccagcaggag aatgtgttcc      900

ttcccaccac aagacccccc tgtgttgagg acctgcaccg ccaagccaag ctcaacctca      960

aatcagtact gagggaatgc gataagttgc ggcatgatgg ctaccgcagt tctcagtact     1020

actctcaggg acccaccttt gcggccaacg ccagcccatt ctgtgatgat taccaagatg     1080

aagatgaaga aacagatcaa aagtgttctc tgtcttcatc agaagaagaa agatttattt     1140

ccatcaggag acctaaaaca ccagcctcaa gtgacttctc cgaccttaat actcagacga     1200

actggaccaa gtcgcttcca ctgccaacac cagaagagaa gatgcgacag caagcccaaa     1260

cagtccaggc tgacgtggtg cctattaaca taactgcatc aggcactggc caagatgatg     1320

ctgatggcca ctcagtgtac acccctgatc actactctac actaggaagg ttcaatagct     1380

gtcggtctgc tgggcagcgc tcagaaacca gggactccag ctgtcagacg gaggatgtga     1440

aggtcgtacc accttccatg aggagaatca gggcacagaa ggggcaaggc attgctgccc     1500

agatgggcca cttctcaggt tcctctggca acatgtctgt gctgagcgat tctgcaggga     1560

tcgtattccc ttcccgcctt gacagtgatg ctggcttcca tagtcttccg cgttctggag     1620

caagggcaaa cattcagtcc cttgagccga ggctgggtgc cctcggccct gcaggagaca     1680

tgaatggcac tttcctctac cagagaggtc acccacaagc agatgaaaac ttaggccatt     1740

taggaggtgc ctcagggact ggaacacttt tgagacccaa atcccaggag ttgagacact     1800

tcgagagtga aaatataatg agcccagcgt gtgtggtttc tcctcatgca acctactcca     1860

ccagcatcat cccaaatgcc acactgtctt cctcttccga ggtcatcgct attcccactg     1920

ctcagagtgc gggacagcgg gaaagtaaaa gttctggctc atcacatgca aggataaaat     1980

ccagagacca cctcatctcc aggcatgctg tgaaaggtga tcctcagtct cccggtcgcc     2040

actggaatga gggccatgcc accattcttt cacaggactt agaccctcat tcccctggtg     2100

aacccgcact gttgtccctc tgtgactcag ccgtccctct aaatgctcca gcaaataggg     2160

agaatgggtc ccaagctatg ccgtataatt gtagaaacaa cctggccttc ccagcccacc     2220

cccaagatgt ggatggcaag agtgaatcta gttattcagg gggcggaggg cacagcagct     2280

cggagccctg ggaatacaaa tcctcaggta atggaagggc atcccccctg aagccgcatt     2340

tagcaactcc tggctattcc actcccacaa gtaacatgag cagctgcagt ttggaccaaa     2400

cgtccaacaa agaggatgct gggtcgctgt attctgagga ccacgatggc tactgtgcat     2460

ctgtgcacac tgactctgga catggatctg ggaatctgtg caatagcagt gatggctttg     2520

ggaaccccag gcacagcgtg atcaatgttt ttgttggaag agctcagaaa aaccaagggg     2580

accggtccaa ttaccaggat aaatccctat caagaaacat ctctttgaag aaagcaaaga     2640

agcctcccct gccaccctcc cggacagact ccctccgcag gattcccaag aagagcagcc     2700

agtgcaacgg gcaggtgctc aacgagagcc tgatcgccac actccagcac tcgctgcagc     2760

tgagcctccc aggcaagagt ggcagctcgc cctcccagag cccctgcagt gacttggaag     2820

agccctggct gccccgctcc cggagccaga gcacagttag tgctggcagc agcatgactt     2880

ccgccaccac ccccaatgtc tactccctgt gcggggccac gccatcgcag agtgacacaa     2940

gcagcgtcaa gtcagagtac acggacccct ggggttatta cattgactac acgggcatgc     3000

aggaagatcc ggggaacccg gcagggggct gttcaaccag cagtggggtg cccactggga     3060

acgggccagt ccgccatgtc caagaagggt ccagagccac aatgccccaa gtgcccggtg     3120

gttcagtcaa accaaagatc atgtcaccag agaagtcaca cagagtcatt tctccatcca     3180

gtgggtattc cagccagtcg aatacaccca cagcactcac ccctgtgcct gtgtttttaa     3240

aatcagtgtc accagcaaac gggaagggga agcccaagcc caaggtacca gaaaggaagt     3300

cctctctgat atcttcagta tccatttcct catcgtccac ttctctttct tctagtactt     3360

ctactgaagg aagtggcact atgaagaagc tggatccagc cgtgggctct cccccggctc     3420

ctcctcctcc tcctgttccc tctcctccat tcccttgtcc tgcagacagg tctcctttcc     3480

ttcctccccc acctcctgtc acagattgct cccagggctc tcctctgcct cactctcctg     3540

tgttcccccc tccgccgcca gaagctctca ttcctttctg ctccccacct gattggtgcc     3600

tttctcctcc ccgccctgca ctgagcccca ttcttccaga ttcacctgtg tccttgccat     3660

tgcccccacc tctcttacct tcctcggaac ccccacctgc cccacctctt gaccccaaat     3720

tcatgaaaga caccaggccg cctttcacaa attctggcca gccagaatcc tcccggggat     3780

ccttgaggcc gccttctacc aaggaggaga ccagcaggcc ccccatgccc ctgataacca     3840

cggaagcatt gcagatggtg cagttgaggc ccgtgagaaa gaactcaggc gctgaggcgg     3900

cacagttgtc tgaacgaaca gctcaggaac aacgaactcc agttgctcca cagtaccact     3960

taaagccatc tgctttcctg aaatcccgaa atagcacaaa tgaaatggag agtgaaagcc     4020

agcctgcctc tgtgacaagc tcgcttccga cgcctgccaa gagctcgagt cagggtgacc     4080

atggcagtgc ggctgagcgt ggtggccctg tgagccgcag ccctggagct ccaagcgctg     4140

gggaggcaga ggctcggccc agccccagca ccaccccact cccagactct tcacccagca     4200

ggaagccacc ccccatttcc aagaagccca aactgttcct ggtggtacca cctccgcaga     4260

aagattttgc agtggagccc gcagagaacg tgagcgaagc cctccgagct gtgcccagcc     4320

ccacgacggg agaggagggc tctgtgcaca gcagggaggc aaaagagagt tctgcagccc     4380

aagctggctc tcatgccacg caccctggca cctcggttct tgagggagga gctgcaggat     4440

ccatgtctcc cagcagagtg gaagccaatg tccccatggt tcagcctgat gtctcaccag     4500

cccccaagca ggaggagcca gccgagaaca gtgcggatac tgggggcgat ggggagagct     4560

gcctatctca acaggacgga gcagctgggg tgccggagac caacgcagcc ggttcatcct     4620

cagaggcctg tgacttcctc aaggaagacg ggaatgatga ggtaatgacc cccagtcgac     4680

ccaggaccac agaagacctt tttgcagcta ttcacagatc caaaaggaaa gtcctcggcc     4740

gtagagattc agatgatgac cactcccgaa accattctcc ctccccgccc gtgacaccca     4800

ccggcgctgc cccaagcctg gcctctccaa agcaagtggg gtcgattcag agaagcatcc     4860

gaaagagcag caccagcagt gacaacttca aagctctgct gctgaaaaag ggcagtcgtt     4920

cagacaccag cgcccgcatg tctgcagcag agatgctcaa gaacacagac cctagattcc     4980

agaggtcgag gtcagagcct tccccagatg cccccgagag cccgtcaagc tgctccccaa     5040

gcaagaacag aagggcgcag gaggagtggg ccaagaacga aggcttgatg cctcggagtc     5100

tgtccttttc cggccccagg tacggccgca gccgaacgcc gccttctgcc gccagcagca     5160

ggtacagcat gcggaaccgg atccagagca gccccatgac cgtcatctcg gagggagaag     5220

gggaagccgt ggagcctgtg gacagcatag cccgcggggc tctgggcgct gcggagggat     5280

gttccctgga cggactggcg agggaggaga tggacgaggg cggcctgctc tgtggggagg     5340

ggcctgccgc ctccctgcag ccccaggccc ccggccctgt ggatgggaca gccagtgcag     5400

agggcagaga gccctcccca cagtgtggcg gttctctgag cgaggagagt tagggccaag     5460

aacgtaactc tcccaggtga cacgggggga gacgagcaat gcagcactct aggaagcctg     5520

ctaggcgccc ttccctggct cacccgggga gcccactctg cttctgtgct gtgggccccg     5580

gggttgccag ccctgcagtg tgagtgaacg gttatttagg actcacctgg cacttgccct     5640

gtggcttaag aacaagtaga agcttaaact tctgaaagtg cttcccgggg aagatttttt     5700

tttttttttt ttttttttgc taaatgctgg gtgtgtatgt gtgcattttc cacacttttt     5760

aatttttaaa aaatacacat atacacaaac aacatgtaca gaaatagaag aaagcaagcc     5820

agacttaagc ttggtagagt aacggagtcc tctggtctag gcggtaattg ctttcagaga     5880

attacgttta tagaaatcag cgagttttgt aagaaaggag aagatgttac ttcaagaaag     5940

aggcagtaga gttgctggtt cttaatgcac agaacacaca gatatatgca cacgtgtgct     6000

gctgaggtga ggcaggtctg gtgagcacgg agaggctggg aaggggctaa gtgactaatt     6060

ggttcaggta cttttttctg ggggaggtag actttgcttc ttttttgtaa aaatgacaaa     6120

cgtagaagtg gcaatgctgt aacctggtgc ctgctgctgt gcagccacat acacacaatt     6180

gtagcctgat ttttagaagt gtgggtaatt ttttaatgaa tttcctcctt gagtagcagc     6240

tgaggtcatt gacaactgaa gtgatggtgt ggacatagag agaggggaag ggttggaaag     6300

gagtaagtga tacactgctg gaatttgttt cctgcctatg aaataaaatt atttttcaga     6360

attaaatttg aaaacttgca ctacagaact atgggtggag cttttccttt tacaacagtt     6420

tttttttttt ttttttttta accagagttt aaacttccat taggcaattt cctgtcactt     6480

gaaatgtcaa catttgctaa cttttggata tccttttggt tacaccaaag aaaaagttat     6540

ggctattttt ttttccttga actgcctaca gtatcatgtc ctaattcaga aagatttatc     6600

aaaatctatt atatattatc ttactttgaa gaaaatgctg aatagctctt gttagtcaaa     6660

taaactgata aaaattggta gggcctggct atcaattagc cctgggaaat gaatttttag     6720

attaaaaagg tttttttgca tcatttggtt tgtgcatttt tatatttgtt tataaataat     6780

tgagttgcta attacttcta atcttctcca atcagatttt caacaatttt agacatggga     6840

cacacgtgtg tgaagtcttt attttaatgt aataatctca ttacccccac ccttactccc     6900

ttaacttcca tgtacttaga ctcctttatt tgttaaataa actagagtat tgtcttcttc     6960

attagaagga cctaggatga caatgcggag agtcttggtc tgaatctagt gcgactacca     7020

cctgccagct tttggggggt atggaaatac tatctaaaag ttggactgca tgggtcaaat     7080

cattatgaga cttataaact aaaactttag atacccatat agaaatgtct ttgaggcaaa     7140

aacaaaccta aagaatgaag gctctttccc ttctctgaaa aaaacaaaac actgctcttc     7200

acacaaccgg aagtcaagac cagagatttg gagcaattgt ctactaattt ggcacaaaga     7260

tcgtttcttt agaaaagtgg cattggcttt tgaatatgaa atcttctcat agctgcctaa     7320

aaaagactag aatgtatatg gatatcagaa acctttaata atacataatt tatgcaaaga     7380

taagataaag caacataaca ctaattataa aactattttt aaatccccat ttttaatgaa     7440

aaatatacat ttgtatttaa tttcctttga ataaaacaat tgtaaagtaa a              7491


<210>  2502
<211>  7491
<212>  DNA
<213>  homo sapiens

<400>  2502
acagacggga aggagagcaa gtgggcggtt tatgattctg ccctgtgctg gggcgagtga       60

gctgagctct ttgatttctc ccaagtaacc gtgtgggtga actgtaaact gggtgcctgg      120

cttgaccctg actctttttc tctagggtga ggagttactt caccagggca gctggctttc      180

tgccctggtg gggaaagatg cccaggagag gagtaggatt acaatttggg atgctaggga      240

cacgccaaag agtcggggtg ccttggcttt gtgttttgca aagtcctgac aagtactcct      300

gaaatgaaca cgctgcttca ttttttaaat tatactttta tttgtttatt attttttggc      360

cgtggatatc gcggatctag aaacggagtc cacaatgtgg ctagggtaaa acatttttct      420

tttctttctt aacccctcct tttccctttc tttttaattg ggtgacacag aagccgtctt      480

tttggataat gcggtgcctg actgtcagcg ttgtctaaga gggaaacagc aggctcgtgg      540

agaggacctg ggccaacgca aaaaacccag cgttttgttt gctgggctgt tctttgtctc      600

tagttgattt tgaaaagaag atgaaaaagg aaggctcttc aggttccttc agactccagc      660

cgaatacagg ttctctctca cgtgctgtaa gttggataaa tttctcctcc ttgtccaggc      720

agacaaagag gctgtttcgc agtgatggag agctctcggt ttgtgggcag caggtggaag      780

tggatgacga aaactggata tacagagccc agcccagaaa agcggtttcc aacctagatg      840

aggaaagccg atggacagtc cactacactg ccccgtggca ccagcaggag aatgtgttcc      900

ttcccaccac aagacccccc tgtgttgagg acctgcaccg ccaagccaag ctcaacctca      960

aatcagtact gagggaatgc gataagttgc ggcatgatgg ctaccgcagt tctcagtact     1020

actctcaggg acccaccttt gcggccaacg ccagcccatt ctgtgatgat taccaagatg     1080

aagatgaaga aacagatcaa aagtgttctc tgtcttcatc agaagaagaa agatttattt     1140

ccatcaggag acctaaaaca ccagcctcaa gtgacttctc cgaccttaat actcagacga     1200

actggaccaa gtcgcttcca ctgccaacac cagaagagaa gatgcgacag caagcccaaa     1260

cagtccaggc tgacgtggtg cctattaaca taactgcatc aggcactggc caagatgatg     1320

ctgatggcca ctcagtgtac acccctgatc actactctac actaggaagg ttcaatagct     1380

gtcggtctgc tgggcagcgc tcagaaacca gggactccag ctgtcagacg gaggatgtga     1440

aggtcgtacc accttccatg aggagaatca gggcacagaa ggggcaaggc attgctgccc     1500

agatgggcca cttctcaggt tcctctggca acatgtctgt gctgagcgat tctgcaggga     1560

tcgtattccc ttcccgcctt gacagtgatg ctggcttcca tagtcttccg cgttctggag     1620

caagggcaaa cattcagtcc cttgagccga ggctgggtgc cctcggccct gcaggagaca     1680

tgaatggcac tttcctctac cagagaggtc acccacaagc agatgaaaac ttaggccatt     1740

taggaggtgc ctcagggact ggaacacttt tgagacccaa atcccaggag ttgagacact     1800

tcgagagtga aaatataatg agcccagcgt gtgtggtttc tcctcatgca acctactcca     1860

ccagcatcat cccaaatgcc acactgtctt cctcttccga ggtcatcgct attcccactg     1920

ctcagagtgc gggacagcgg gaaagtaaaa gttctggctc atcacatgca aggataaaat     1980

ccagagacca cctcatctcc aggcatgctg tgaaaggtga tcctcagtct cccggtcgcc     2040

actggaatga gggccatgcc accattcttt cacaggactt agaccctcat tcccctggtg     2100

aacccgcact gttgtccctc tgtgactcag ccgtccctct aaatgctcca gcaaataggg     2160

agaatgggtc ccaagctatg ccgtataatt gtagaaacaa cctggccttc ccagcccacc     2220

cccaagatgt ggatggcaag agtgaatcta gttattcagg gggcggaggg cacagcagct     2280

cggagccctg ggaatacaaa tcctcaggta atggaagggc atcccccctg aagccgcatt     2340

tagcaactcc tggctattcc actcccacaa gtaacatgag cagctgcagt ttggaccaaa     2400

cgtccaacaa agaggatgct gggtcgctgt attctgagga ccacgatggc tactgtgcat     2460

ctgtgcacac tgactctgga catggatctg ggaatctgtg caatagcagt gatggctttg     2520

ggaaccccag gcacagcgtg atcaatgttt ttgttggaag agctcagaaa aaccaagggg     2580

accggtccaa ttaccaggat aaatccctat caagaaacat ctctttgaag aaagcaaaga     2640

agcctcccct gccaccctcc cggacagact ccctccgcag gattcccaag aagagcagcc     2700

agtgcaacgg gcaggtgctc aacgagagcc tgatcgccac actccagcac tcgctgcagc     2760

tgagcctccc aggcaagagt ggcagctcgc cctcccagag cccctgcagt gacttggaag     2820

agccctggct gccccgctcc cggagccaga gcacagttag tgctggcagc agcatgactt     2880

ccgccaccac ccccaatgtc tactccctgt gcggggccac gccatcgcag agtgacacaa     2940

gcagcgtcaa gtcagagtac acggacccct ggggttatta cattgactac acgggcatgc     3000

aggaagatcc ggggaacccg gcagggggct gttcaaccag cagtggggtg cccactggga     3060

acgggccagt ccgccatgtc caagaagggt ccagagccac aatgccccaa gtgcccggtg     3120

gttcagtcaa accaaagatc atgtcaccag agaagtcaca cagagtcatt tctccatcca     3180

gtgggtattc cagccagtcg aatacaccca cagcactcac ccctgtgcct gtgtttttaa     3240

aatcagtgtc accagcaaac gggaagggga agcccaagcc caaggtacca gaaaggaagt     3300

cctctctgat atcttcagta tccatttcct catcgtccac ttctctttct tctagtactt     3360

ctactgaagg aagtggcact atgaagaagc tggatccagc cgtgggctct cccccggctc     3420

ctcctcctcc tcctgttccc tctcctccat tcccttgtcc tgcagacagg tctcctttcc     3480

ttcctccccc acctcctgtc acagattgct cccagggctc tcctctgcct cactctcctg     3540

tgttcccccc tccgccgcca gaagctctca ttcctttctg ctccccacct gattggtgcc     3600

tttctcctcc ccgccctgca ctgagcccca ttcttccaga ttcacctgtg tccttgccat     3660

tgcccccacc tctcttacct tcctcggaac ccccacctgc cccacctctt gaccccaaat     3720

tcatgaaaga caccaggccg cctttcacaa attctggcca gccagaatcc tcccggggat     3780

ccttgaggcc gccttctacc aaggaggaga ccagcaggcc ccccatgccc ctgataacca     3840

cggaagcatt gcagatggtg cagttgaggc ccgtgagaaa gaactcaggc gctgaggcgg     3900

cacagttgtc tgaacgaaca gctcaggaac aacgaactcc agttgctcca cagtaccact     3960

taaagccatc tgctttcctg aaatcccgaa atagcacaaa tgaaatggag agtgaaagcc     4020

agcctgcctc tgtgacaagc tcgcttccga cgcctgccaa gagctcgagt cagggtgacc     4080

atggcagtgc ggctgagcgt ggtggccctg tgagccgcag ccctggagct ccaagcgctg     4140

gggaggcaga ggctcggccc agccccagca ccaccccact cccagactct tcacccagca     4200

ggaagccacc ccccatttcc aagaagccca aactgttcct ggtggtacca cctccgcaga     4260

aagattttgc agtggagccc gcagagaacg tgagcgaagc cctccgagct gtgcccagcc     4320

ccacgacggg agaggagggc tctgtgcaca gcagggaggc aaaagagagt tctgcagccc     4380

aagctggctc tcatgccacg caccctggca cctcggttct tgagggagga gctgcaggat     4440

ccatgtctcc cagcagagtg gaagccaatg tccccatggt tcagcctgat gtctcaccag     4500

cccccaagca ggaggagcca gccgagaaca gtgcggatac tgggggcgat ggggagagct     4560

gcctatctca acaggacgga gcagctgggg tgccggagac caacgcagcc ggttcatcct     4620

cagaggcctg tgacttcctc aaggaagacg ggaatgatga ggtaatgacc cccagtcgac     4680

ccaggaccac agaagacctt tttgcagcta ttcacagatc caaaaggaaa gtcctcggcc     4740

gtagagattc agatgatgac cactcccgaa accattctcc ctccccgccc gtgacaccca     4800

ccggcgctgc cccaagcctg gcctctccaa agcaagtggg gtcgattcag agaagcatcc     4860

gaaagagcag caccagcagt gacaacttca aagctctgct gctgaaaaag ggcagtcgtt     4920

cagacaccag cgcccgcatg tctgcagcag agatgctcaa gaacacagac cctagattcc     4980

agaggtcgag gtcagagcct tccccagatg cccccgagag cccgtcaagc tgctccccaa     5040

gcaagaacag aagggcgcag gaggagtggg ccaagaacga aggcttgatg cctcggagtc     5100

tgtccttttc cggccccagg tacggccgca gccgaacgcc gccttctgcc gccagcagca     5160

ggtacagcat gcggaaccgg atccagagca gccccatgac cgtcatctcg gagggagaag     5220

gggaagccgt ggagcctgtg gacagcatag cccgcggggc tctgggcgct gcggagggat     5280

gttccctgga cggactggcg agggaggaga tggacgaggg cggcctgctc tgtggggagg     5340

ggcctgccgc ctccctgcag ccccaggccc ccggccctgt ggatgggaca gccagtgcag     5400

agggcagaga gccctcccca cagtgtggcg gttctctgag cgaggagagt tagggccaag     5460

aacgtaactc tcccaggtga cacgggggga gacgagcaat gcagcactct aggaagcctg     5520

ctaggcgccc ttccctggct cacccgggga gcccactctg cttctgtgct gtgggccccg     5580

gggttgccag ccctgcagtg tgagtgaacg gttatttagg actcacctgg cacttgccct     5640

gtggcttaag aacaagtaga agcttaaact tctgaaagtg cttcccgggg aagatttttt     5700

tttttttttt ttttttttgc taaatgctgg gtgtgtatgt gtgcattttc cacacttttt     5760

aatttttaaa aaatacacat atacacaaac aacatgtaca gaaatagaag aaagcaagcc     5820

agacttaagc ttggtagagt aacggagtcc tctggtctag gcggtaattg ctttcagaga     5880

attacgttta tagaaatcag cgagttttgt aagaaaggag aagatgttac ttcaagaaag     5940

aggcagtaga gttgctggtt cttaatgcac agaacacaca gatatatgca cacgtgtgct     6000

gctgaggtga ggcaggtctg gtgagcacgg agaggctggg aaggggctaa gtgactaatt     6060

ggttcaggta cttttttctg ggggaggtag actttgcttc ttttttgtaa aaatgacaaa     6120

cgtagaagtg gcaatgctgt aacctggtgc ctgctgctgt gcagccacat acacacaatt     6180

gtagcctgat ttttagaagt gtgggtaatt ttttaatgaa tttcctcctt gagtagcagc     6240

tgaggtcatt gacaactgaa gtgatggtgt ggacatagag agaggggaag ggttggaaag     6300

gagtaagtga tacactgctg gaatttgttt cctgcctatg aaataaaatt atttttcaga     6360

attaaatttg aaaacttgca ctacagaact atgggtggag cttttccttt tacaacagtt     6420

tttttttttt ttttttttta accagagttt aaacttccat taggcaattt cctgtcactt     6480

gaaatgtcaa catttgctaa cttttggata tccttttggt tacaccaaag aaaaagttat     6540

ggctattttt ttttccttga actgcctaca gtatcatgtc ctaattcaga aagatttatc     6600

aaaatctatt atatattatc ttactttgaa gaaaatgctg aatagctctt gttagtcaaa     6660

taaactgata aaaattggta gggcctggct atcaattagc cctgggaaat gaatttttag     6720

attaaaaagg tttttttgca tcatttggtt tgtgcatttt tatatttgtt tataaataat     6780

tgagttgcta attacttcta atcttctcca atcagatttt caacaatttt agacatggga     6840

cacacgtgtg tgaagtcttt attttaatgt aataatctca ttacccccac ccttactccc     6900

ttaacttcca tgtacttaga ctcctttatt tgttaaataa actagagtat tgtcttcttc     6960

attagaagga cctaggatga caatgcggag agtcttggtc tgaatctagt gcgactacca     7020

cctgccagct tttggggggt atggaaatac tatctaaaag ttggactgca tgggtcaaat     7080

cattatgaga cttataaact aaaactttag atacccatat agaaatgtct ttgaggcaaa     7140

aacaaaccta aagaatgaag gctctttccc ttctctgaaa aaaacaaaac actgctcttc     7200

acacaaccgg aagtcaagac cagagatttg gagcaattgt ctactaattt ggcacaaaga     7260

tcgtttcttt agaaaagtgg cattggcttt tgaatatgaa atcttctcat agctgcctaa     7320

aaaagactag aatgtatatg gatatcagaa acctttaata atacataatt tatgcaaaga     7380

taagataaag caacataaca ctaattataa aactattttt aaatccccat ttttaatgaa     7440

aaatatacat ttgtatttaa tttcctttga ataaaacaat tgtaaagtaa a              7491


<210>  2503
<211>  4580
<212>  DNA
<213>  homo sapiens

<400>  2503
gtagttttct ggacccacgg gacgggcagg agctggagct ccgtgccgcc tgtactcccg       60

ccttcatttc ccatcgtgct gaggcgggtg gcatggcgga gaaggatgac accggagttt      120

gacgaagagg tggtttttga gaattctcca ctttaccaat acttacagga tctgggacac      180

acagactttg aaatatgttc ttctttgtca ccaaaaacag aaaaatgcac aacagaggga      240

caacaaaagc ctcctacaag agtcctacca aaacaaggta tcctgttaaa agtggctgaa      300

accatcaaaa gttggatttt tttttctcag tgcaataaga aagatgactt acttcacaag      360

ttggatattg gattccgact cgactcatta cataccatcc tgcaacagga agtcctgtta      420

caagaggatg tggagctgat tgagctactt gatcccagta tcctgtctgc agggcaatct      480

caacaacagg aaaatggaca ccttccaaca ctttgctccc tggcaacccc taatatttgg      540

gatctctcaa tgctatttgc cttcattagc ttgctcgtta tgcttcccac ttggtggatt      600

gtgtcttcct ggctggtatg gggagtgatt ctatttgtgt atctggtcat aagagctttg      660

agattatgga ggacagccaa actacaagtg accctaaaaa aatacagcgt tcatttggaa      720

gatatggcca caaacagccg agcttttact aacctcgtga gaaaagcttt acgtctcatt      780

caagaaaccg aagtgatttc cagaggattt acactggtca gtgctgcttg cccatttaat      840

aaagctggac agcatccaag tcagcatctc atcggtcttc ggaaagctgt ctaccgaact      900

ctaagagcca acttccaagc agcaaggcta gctaccctat atatgctgaa aaactacccc      960

ctgaactctg agagtgacaa tgtaaccaac tacatctgtg tggtgccttt taaagagctg     1020

ggccttggac ttagtgaaga gcagatttca gaagaggaag cacataactt tacagatggc     1080

ttcagcctgc ctgcattgaa ggttttgttc caactctggg tggcacagag ttcagagttc     1140

ttcagacggt tagccctatt actttctaca gccaattcac ctcctgggcc cttacttact     1200

ccagcacttc tgcctcatcg tatcttatct gatgtgactc aaggtctacc tcatgctcat     1260

tctgcctgtt tggaagagct taagcgcagc tatgagttct atcggtactt tgaaactcag     1320

caccagtcag taccgcagtg tttatccaaa actcaacaga agtcaagaga actgaataat     1380

gttcacacag cagtgcgtag cttgcagctc catctgaaag cattactgaa tgaggtaata     1440

attcttgaag atgaacttga aaagcttgtt tgtactaaag aaacacaaga actagtgtca     1500

gaggcttatc ccatcctaga acagaaatta aagttgattc agccccacgt tcaagcaagc     1560

aacaattgct gggaagaggc catttctcag gtcgacaaac tgctacgaag aaatacagat     1620

aaaaaaggca agcctgaaat agcatgtgaa aacccacatt gtacagtagt acctttgaag     1680

cagcctactc tacacattgc agacaaagat ccaatcccag aggagcagga attagaagct     1740

tatgtagatg atatagatat tgatagtgat ttcagaaagg atgattttta ttacttgtct     1800

caagaagaca aagagagaca gaagcgtgag catgaagaat ccaagagggt gctccaagaa     1860

ttaaaatctg tgctgggatt taaagcttca gaggcagaaa ggcagaagtg gaagcaactt     1920

ctatttagtg atcatgccgt gttgaaatcc ttgtctcctg tagacccagt ggaacccata     1980

agtaattcag aaccatcaat gaattcagat atgggaaaag tcagtaaaaa tgatactgaa     2040

gaggaaagta ataaatccgc cacaacagac aatgaaataa gtaggactga gtatttatgt     2100

gaaaactctc tagaaggtaa aaataaagat aattcttcaa atgaagtctt cccccaagga     2160

gcagaagaaa gaatgtgtta ccaatgtgag agtgaagatg aaccacaagc agatggaagt     2220

ggtctgacca ctgcccctcc aactcccagg gactcattac agccctccat taagcagagg     2280

ctggcacggc tacagctgtc accagatttt accttcactg ctggccttgc tgcagaagtg     2340

gctgctagat ctctctcctt taccaccatg caggaacaga cttttggtgg tgaggaggaa     2400

gaacaaataa tagaagaaaa taaaaatgag atagaagaaa agtaagaacc aagattcata     2460

tgaagtgata ttagattgtt ccttttacaa aagtgtttag cttcaagact ggaaagggaa     2520

tatgagtgta agtttactat atataaagct aagatgtgga tttacaggaa gaaccctggt     2580

ttgaataact gatctgaaat tagtagttac ctgtaaatgg cagatctttt aggaaaataa     2640

gagaaaggta agggctcttt tgaataaact gctgttttat ttgtggcaca actgatcaat     2700

cttggaaatt ctttaagtat ttttaataag aaatgaatta tcatttcttg ccagaatttg     2760

ctaccttaag gtgattggga aaattctgtt gcaagaacat taacatttag tatgactcct     2820

ttttactgta ttcttgcagt taataactgc agctattatg ttaataacaa gttgtttgta     2880

ttttattttt gtttatacca gtcttaaaga tccaggttct gaataaaaaa attaattgat     2940

acaattgatg tgtgctgggg tttggaacta aaagtagttt caacagtgcg tgggttatga     3000

catttcttat gtttctttgt tcatgtgtgt atttagtagt taattttaag atgtcctagt     3060

gatctttaaa agaaaaatat tgtaccattt tttagaatta cactttcacc tttctttttg     3120

caattgaaag tgatgatgtc aaagtgggat ttctgtactc caaggcccca cccccaattt     3180

agcaagcaga aaaacgttcc ttgtatcact ttaccttgga taattgggtg ccattaacac     3240

aaacaggtca caatcctgct gttttctagc cctgtccacc ataatgagat tcaggaaaca     3300

tcctgtcagc ctcctggaaa gcatccttgt ctccttagta tttcatttac aaactacctc     3360

ttaacagaga ctgcttttca aattggccaa tcttacctgt tttgtgttgt gattgcattt     3420

tcaaagagta attattttca gcatatacag ttttgaaacc tgtagctcct atgcaataac     3480

atagttctat agacattatt tgggggaaat gtagtaataa ctcaatctat gttgctgtcc     3540

tagaaaggaa attgcatgat gaatctagat tgtctttaga gtaaagaaac acattcaaat     3600

tcctgtaact tatcactttc agtgagtaaa tttacttata ccaaagggga ttttttttct     3660

ttcaggaatc taaggaaatt tactttttaa cctgagaaaa aaacttggtt ctgctttata     3720

taaacagtag agattattgt actataagtg attttgcctt tttgccaaaa tcctggaact     3780

catctataat taacctcttc ggagcaatac cttaggttgg gccttgcttt actacttaga     3840

aatagctaaa tttcaatttt aaaaatcttt gtgtgttata actgttaaat tattcaataa     3900

tacttagggt ttactttctt atttaaatca cttatttagt ttaccgactt catttttctt     3960

tggatttaga agaagcaatt atggaaaaac ttggtaatct ctctcaacct ataaccttac     4020

acaggaagaa ttagagttta ataattttta attcttttat tgtatgttac ttttattaca     4080

ccagtttggg ggaaaatctt cataaaattg tatcagtttt attcagtgtt ctctaaggtg     4140

atacctttta attttgaaag actaaataat tttaatcgag aatttccagt ctttcagtct     4200

gatctattta attcactact tgttacataa tccagtgaaa actctacttg ttgaaattat     4260

gacataaaga tcttgcagct ttatttgagt atttgttctt ttgtgtagtt tccatctttt     4320

aaaatattta aaatattttc aagataaagt attatcttct ctgcaaaaat tcctggagta     4380

attttctctc ataatatttg aagtcagtgg ttctcagttg tattagtggg gtaactacat     4440

caaaataaat aaagtcttat ttttaaaatg caaattttag accatactcc cagtgattct     4500

tagttggtct ttttggaatg agccataggt aatgtttatg tccaataaaa tctaggaacc     4560

tcaaaaaaaa aaaaaaaaaa                                                 4580


<210>  2504
<211>  2822
<212>  DNA
<213>  homo sapiens

<400>  2504
ggcgcggtac aggagcagca ctgccggcgg gggcgggtgc cagggacttg gaggtggagg       60

ggacgcggcg gtactctggc gtcttccgac ttcgactcct taccttaaaa gatgctggag      120

tcatatgtaa ctccaatttt aatgagctat gtgaatcgct acatcaagaa cttaaagccg      180

tcggatctac agctttcact atggggtgga gacgtggtac tcagcaagct cgagttaaag      240

ttggatgtgc tggaacagga actgaaatta ccattcactt ttttaagtgg acatattcat      300

gaattgagga ttcatgtacc atggacaaaa ctgggttcag aaccagtggt aattaccatc      360

aatactatgg aatgcatttt gaaacttaag gatgggatac aggatgacca tgaaagctgt      420

ggttctaatt ctaccaaccg tagtactgct gagagcacaa aatcatcaat caaaccgcgg      480

agaatgcagc aggctgctcc tacagatcct gacttaccac caggttatgt gcagagtctg      540

attagacgag ttgtaaataa tgtaaacatt gtgataaata atctcatact aaaatatgtt      600

gaagatgata tcgtcctttc cgtcaatatc acttctgcag aatgttatac agtaggtgaa      660

ttatgggatc gtgcattcat ggatatttct gcaactgatt tggtgctgag aaaggttatc      720

aatttttctg actgtacagt ttgtcttgat aaacggaatg ccagtggtaa aatagaattt      780

taccaggatc ctttattata caaatgttcc ttcagaactc gtcttcattt tacatatgaa      840

aacctaaatt ccaagatgcc atctgttatt aaaattcata ctttagtgga aagtttgaaa      900

ctttctatca cagatcaaca actgcctatg tttattcgta taatgcaact tggaattgct      960

ctttactatg gagaaatagg caattttaaa gaaggcgaaa tagaggacct tacttgtcat     1020

aataaagata tgctaggaaa cattacaggt tctgaagatg aaacaagaat agatatgcaa     1080

tatcctgctc agcataaagg tcaagagtta tattcacagc aagatgagga gcagccacag     1140

ggatgggtgt catgggcctg gtcctttgtg cctgcaattg tgagttatga cgatggcgag     1200

gaagactttg ttgggaacga tcctgcatca accatgcatc aacaaaaagc acagactttg     1260

aaggatccta ttgtttctat aggattttat tgcacaaagg caacggtgac tttcaaactc     1320

acagaaatgc aagttgagag tagttattac agtccacaga aagtaaaatc taaagaagta     1380

ttgtgttggg aacaagaagg aactacagtt gaggccctta tgatgggaga acctttcttt     1440

gattgccaga ttgggtttgt tggttgcaga gccatgtgcc ttaaaggaat tatgggtgtt     1500

aaagattttg aagagaatat gaatagaagt gaaactgaag cctgtttctt catttgtggt     1560

gacaatttga gtacgaaagg tttcacatac cttacaaatt cattgtttga ttaccgaagc     1620

ccagaaaata atggtactcg cgcagaattt atcttggatt caactcatca taaggagaca     1680

tacactgaga tagctggaat gcaacggttt ggggcttttt atatggatta cctgtataca     1740

atggagaaca ctagtggcaa aggttccaca aatcaacaag acttttcttc agggaaaagt     1800

gaagatttgg gaacagttca ggagaagtcc accaaaagcc ttgttatagg tcctcttgat     1860

tttcgtttgg atagcagtgc ggtgcatagg attttgaaaa tgattgtgtg tgccttggaa     1920

catgaatatg aaccatatag caggctaaaa tcagatatta aggatgaaaa tgaaacaata     1980

ctgaatcctg aagaggtggc tcttctggag gaatatattc ctactcgaca tacaagtgtt     2040

actctcctca aatgtacctg cacaatttcc atggctgaat tcaacttgct ggaccattta     2100

ctacctgtca ttatgggaga aaagaactca agtaacttca tgaatactac aaacttccag     2160

tctcttcggc ctttgccatc cattcgaata ttggtggata aaattaatct ggaacattca     2220

gtgccaatgt atgctgaaca gttggtgcat gtggtcagca gccttactca accttctgat     2280

aacctgcttc attattgtta tgtacactgc tatcttaaga tatttggttt ccaggcagga     2340

ctgacgtctt tggattgcag tggatcttac tgcttacctg taccagttat tccctctttc     2400

agcactgctc tttatgggaa acttctgaaa ctccccacat gctggaccaa aagatctcag     2460

attgctataa ctgaaggtat atttgaactt ccaaatctca caattcaagc tacaagagca     2520

cagacacttc tcttgcaagc aatatatcaa agttggtctc atcttggaaa tgtcagctct     2580

tccgcagtga ttgaagcttt gataaatgaa atcttcctaa gtatagagat tgggtcttgc     2640

tatgttgccc aggttgatct tgaactcctg gcctcaaatg atcctcccac ctcaacctcc     2700

tgaagtgccg ggattggagg cccaagccac tgtgcctggc cctttataaa ttatgttata     2760

atttcatgta atacataatt gtatagtcaa aatggctcac atattaaata ttctttatac     2820

aa                                                                    2822


<210>  2505
<211>  1634
<212>  DNA
<213>  homo sapiens

<400>  2505
ggcgcggtac aggagcagca ctgccggcgg gggcgggtgc cagggacttg gaggtggagg       60

ggacgcggcg gtactctggc gtcttccgac ttcgactcct taccttaaaa gatgctggag      120

tcatatgtaa ctccaatttt aatgagctat gtgaatcgct acatcaagaa cttaaagccg      180

tcggatctac agctttcact atggggtgga gacgtggtac tcagcaagct cgagttaaag      240

ttggatgtgc tggaacagga actgaaatta ccattcactt ttttaagtgg acatattcat      300

gaattgagga ttcatgtacc atggacaaaa ctgggttcag aaccagtggt aattaccatc      360

aatactatgg aatgcatttt gaaacttaag gatgggatac aggatgacca tgaaagctgt      420

ggttctaatt ctaccaaccg tagtactgct gagagcacaa aatcatcaat caaaccgcgg      480

agaatgcagc aggctgctcc tacagatcct gacttaccac caggttatgt gcagagtctg      540

attagacgag ttgtaaataa tgtaaacatt gtgataaata atctcatact aaaatatgtt      600

gaagatgata tcgtcctttc cgtcaatatc acttctgcag aatgttatac agtaggtgaa      660

ttatgggatc gtgcattcat ggatatttct gcaactgatt tggtgctgag aaaggttatc      720

aatttttctg actgtacagt ttgtcttgat aaacggaatg ccagtggtaa aatagaattt      780

taccaggatc ctttattata caaatgttcc ttcagaactc gtcttcattt tacatatgaa      840

aacctaaatt ccaagatgcc atctgttatt aaaattcata ctttagtgga aagtttgaaa      900

ctttctatca cagatcaaca actgcctatg tttattcgta taatgcaact tggaattgct      960

ctttactatg gagaaatagg caattttaaa gaaggcgaaa tagaggacct tacttgtcat     1020

aataaagata tgctaggaaa cattacaggt tctgaagatg aaacaagaat agatatgcaa     1080

tatcctgctc agcataaagg tcaagagtta tattcacagc aagatgagga gcagccacag     1140

ggatgggtgt catgggcctg gtcctttgtg cctgcaattg tgagttatga cgatggcgag     1200

gaagactttg ttgggaacga tcctgcatca accatgcatc aacaaaaagc acagactttg     1260

aaggatccta ttgtttctat aggattttat tgcacaaagg caacggtgac tttcaaagta     1320

ggtcttttct cttgctgttt atatctctat caactttaat gcttaaattt ggattgttag     1380

tacaattcta gctttattca agtttgcttt gcattcagta gatgtgagat agagtctaac     1440

agttcttact tcataaaatt acatggctcc tccacttgaa atctttgaat tctgatccct     1500

tcctgtcttc ttagggcatt ctccacattt cttttttatt agcttcatgg atagtttttt     1560

gccctattga atcattcagt tggtgtacaa acatgcctta atattgtcat taaaaaagaa     1620

aggaacagca aaaa                                                       1634


<210>  2506
<211>  14025
<212>  DNA
<213>  homo sapiens

<400>  2506
ggcgcggtac aggagcagca ctgccggcgg gggcgggtgc cagggacttg gaggtggagg       60

ggacgcggcg gtactctggc gtcttccgac ttcgactcct taccttaaaa gatgctggag      120

tcatatgtaa ctccaatttt aatgagctat gtgaatcgct acatcaagaa cttaaagccg      180

tcggatctac agctttcact atggggtgga gacgtggtac tcagcaagct cgagttaaag      240

ttggatgtgc tggaacagga actgaaatta ccattcactt ttttaagtgg acatattcat      300

gaattgagga ttcatgtacc atggacaaaa ctgggttcag aaccagtggt aattaccatc      360

aatactatgg aatgcatttt gaaacttaag gatgggatac aggatgacca tgaaagctgt      420

ggttctaatt ctaccaaccg tagtactgct gagagcacaa aatcatcaat caaaccgcgg      480

agaatgcagc aggctgctcc tacagatcct gacttaccac caggttatgt gcagagtctg      540

attagacgag ttgtaaataa tgtaaacatt gtgataaata atctcatact aaaatatgtt      600

gaagatgata tcgtcctttc cgtcaatatc acttctgcag aatgttatac agtaggtgaa      660

ttatgggatc gtgcattcat ggatatttct gcaactgatt tggtgctgag aaaggttatc      720

aatttttctg actgtacagt ttgtcttgat aaacggaatg ccagtggtaa aatagaattt      780

taccaggatc ctttattata caaatgttcc ttcagaactc gtcttcattt tacatatgaa      840

aacctaaatt ccaagatgcc atctgttatt aaaattcata ctttagtgga aagtttgaaa      900

ctttctatca cagatcaaca actgcctatg tttattcgta taatgcaact tggaattgct      960

ctttactatg gagaaatagg caattttaaa gaaggcgaaa tagaggacct tacttgtcat     1020

aataaagata tgctaggaaa cattacaggt tctgaagatg aaacaagaat agatatgcaa     1080

tatcctgctc agcataaagg tcaagagtta tattcacagc aagatgagga gcagccacag     1140

ggatgggtgt catgggcctg gtcctttgtg cctgcaattg tgagttatga cgatggcgag     1200

gaagactttg ttgggaacga tcctgcatca accatgcatc aacaaaaagc acagactttg     1260

aaggatccta ttgtttctat aggattttat tgcacaaagg caacggtgac tttcaaactc     1320

acagaaatgc aagttgagag tagttattac agtccacaga aagtaaaatc taaagaagta     1380

ttgtgttggg aacaagaagg aactacagtt gaggccctta tgatgggaga acctttcttt     1440

gattgccaga ttgggtttgt tggttgcaga gccatgtgcc ttaaaggaat tatgggtgtt     1500

aaagattttg aagagaatat gaatagaagt gaaactgaag cctgtttctt catttgtggt     1560

gacaatttga gtacgaaagg tttcacatac cttacaaatt cattgtttga ttaccgaagc     1620

ccagaaaata atggtactcg cgcagaattt atcttggatt caactcatca taaggagaca     1680

tacactgaga tagctggaat gcaacggttt ggggcttttt atatggatta cctgtataca     1740

atggagaaca ctagtggcaa aggttccaca aatcaacaag acttttcttc agggaaaagt     1800

gaagatttgg gaacagttca ggagaagtcc accaaaagcc ttgttatagg tcctcttgat     1860

tttcgtttgg atagcagtgc ggtgcatagg attttgaaaa tgattgtgtg tgccttggaa     1920

catgaatatg aaccatatag caggctaaaa tcagatatta aggatgaaaa tgaaacaata     1980

ctgaatcctg aagaggtggc tcttctggag gaatatattc ctactcgaca tacaagtgtt     2040

actctcctca aatgtacctg cacaatttcc atggctgaat tcaacttgct ggaccattta     2100

ctacctgtca ttatgggaga aaagaactca agtaacttca tgaatactac aaacttccag     2160

tctcttcggc ctttgccatc cattcgaata ttggtggata aaattaatct ggaacattca     2220

gtgccaatgt atgctgaaca gttggtgcat gtggtcagca gccttactca accttctgat     2280

aacctgcttc attattgtta tgtacactgc tatcttaaga tatttggttt ccaggcagga     2340

ctgacgtctt tggattgcag tggatcttac tgcttacctg taccagttat tccctctttc     2400

agcactgctc tttatgggaa acttctgaaa ctccccacat gctggaccaa aagatctcag     2460

attgctataa ctgaaggtat atttgaactt ccaaatctca caattcaagc tacaagagca     2520

cagacacttc tcttgcaagc aatatatcaa agttggtctc atcttggaaa tgtcagctct     2580

tccgcagtga ttgaagcttt gataaatgaa atcttcctaa gtataggtgt gaaatctaag     2640

aatcccctgc caactcttga gggctcaatc cagaatgttg aattgaagta ctgcagcaca     2700

tcattggtca aatgtgcctc tgggaccatg ggatcaataa aaatttgtgc caaagcccca     2760

gttgatagtg gaaaagagaa gttgattccc ttgcttcagg gtccttctga cactaaagac     2820

cttcatagca ccaagtggct caatgagagt agaaagccag agtctctctt agctccagat     2880

ttgatggcct tcacaatcca agttccacaa tatattgact actgccacaa ttccggtgct     2940

gtacttcttt gcagtataca aggactagca gttaatattg acccaatctt atatacgtgg     3000

ctcatctatc agcctcagaa acgaacaagt agacatatgc aacagcagcc tgtggtagct     3060

gttcctcttg ttatgccagt ttgtagaagg aaagaggatg aggtgtctat tggaagtgcc     3120

cccttggcaa agcagcaatc atatcaggcc tctgaatatg ccagcagccc tgtaaaaaca     3180

aaaacggtaa cagaatcccg cccattgtca gttcctgtta aagccatgtt gaatatatct     3240

gaaagctgta gaagtcctga agaaagaatg aaggaattta ttggaattgt ttggaatgca     3300

gtgaagcatc tcacactaca gcttgaagta caatcttgtt gtgtgtttat tccaaatgat     3360

agcctgcctt ccccaagtac aattgtatct ggtgacattc ctggaacagt aagaagttgg     3420

taccatggac aaaccagcat gccgggaaca cttgtcctct gtttgcctca aataaagatt     3480

attagtgctg ggcacaagta tatggaacct ctgcaggaga ttccatttgt tatcccacga     3540

cccatccttg aagaaggtga tgcttttcct tggacgatca gcttgcataa tttcagcata     3600

tatacccttc ttggaaaaca agtgacactt tgcctagtgg aacctatggg ttgcacctcc     3660

actctagctg tcacgtctca aaaactgctt gctacgggac ctgatacacg acattcattt     3720

gttgtctgtc tccatgttga cctagagtca ctagagataa aatgctctaa tccccaggtc     3780

cagctcttct atgaactaac tgatatcatg aataaggtct ggaacaagat tcagaagaga     3840

ggcaatctca acctatctcc aacctctcca gagaccatgg cagggcctgt tcctacttct     3900

ccagttagaa gcagtatagg cacagctcct ccagatacca gcacatgcag cccatctgct     3960

gacattggga ctactactga gggagattct atacaagcag gtgaggaatc accattctca     4020

gattctgtga ccttggaaca aactacaagt aatattggag gaaccagtgg acgtgttagt     4080

ttatggatgc agtgggtgct tcccaaaatt actataaagc tctttgctcc agatcctgaa     4140

aataaaggca cagaggtttg tatggtcagt gaactagaag atctcagtgc ttccatagat     4200

gtccaggatg tatataccaa agtgaaatgt aaaatagaga gtttcaatat tgatcactat     4260

agaagcaggc caggggaagg ttggcagtca ggacattttg aaggagtatt tctacaatgc     4320

aaagaaaaat ctgtgacaac tacaaaactt ctagatggca ctcatcagca gcatggattc     4380

ctctctctga catacacaaa agctgtaaca aaaaatgtcc gccacaagtt aacatcaaga     4440

aatgagcgaa gaagttttca taagttatct gaaggcctaa tggatggttc tcctcatttt     4500

cttcatgaaa ttcttctttc agcacaagct tttgatattg ttctttattt tcctttactt     4560

aatgccattg caagtatatt tcaagcaaaa ctaccaaaga cccaaaaaga gaaaagaaaa     4620

tctcctggtc agcccatgag gacccataca ctgacatccc gcaatttacc tttgatttat     4680

gtcaacacaa gtgtaatcag aatttttatt ccaaaaacag aagaaatgca gccaactgtt     4740

gaagctaatc aggcagcaaa agaagacact gtggttttga agattggctc tgttgccatg     4800

gctccccagg ctgacaatcc ccttggcaga tctgtcctta ggaaagatat ttaccagaga     4860

gccttgaact taggaattct tcgagatcct ggatcagaaa tcgaagacag acaataccaa     4920

atagatctgc agtccatcaa tattggtact gcacagtggc atcaactaaa accagagaag     4980

gaaagtgtct caggaggggt ggtaacagag actgaaagga attctcaaaa tccagccctt     5040

gagtggaata tggccagcag catacggcgg catcaagaaa ggagagcaat tttgaccccc     5100

gttttgacag atttttctgt ccgaataact ggagcacctg ctgtcatttt caccaaagta     5160

gtttctccag aaaatttgca tactgaggag attttagtgt gtggccattc cttagaagtg     5220

aatataacca caaacctgga cttcttccta agtgtggctc aagttcaact cttacatcag     5280

ttaatagtag caaatatgac tggactggaa ccatcaaaca aggctgcaga gatctctaaa     5340

caagaacaga aaaaagtgga tatatttgat ggaggcatgg ctgaaacctc atctcgctac     5400

agtggtgctc aggatagtgg aattggcagt gacagtgtta aaatcagaat agtgcaaata     5460

gagcagcaca gtggtgccag tcagcatcgc attgcccgtc cctcacgcca gtcatcaatt     5520

gtaaaaaatc taaattttat tccctttgac atatttatta ctgcaagtag aatctcacta     5580

atgacctatt cctgtatggc cttatccaaa tcgaaatcac aagaacagaa gaataatgaa     5640

aaaacagaca agagttcatt aaatctccca gaagttgatt cagatgttgc taagcccaac     5700

caggcatgta tttccacggt gacagcagaa gatctcttaa ggagcagcat ttcttttcct     5760

tcagggaaaa aaataggggt cctctctctt gaaagtcttc atgcatccac aaggtcatct     5820

gctagacaag cacttggtat aactattgtt cggcagcctg gtcgaagagg aactggtgac     5880

ttacagctag agccttttct gtactttatt gtgtcccagc cttccttgct tctgagttgt     5940

caccacagaa agcagcgagt ggaagtatcc atttttgatg ctgtgcttaa aggggtggcc     6000

tctgattaca aatgtataga tcctgggaag actctgcctg aagcccttga ttattgcact     6060

gtttggctac agacagtgcc tggagaaata gacagcaaaa gtggtattcc accttccttt     6120

ataacactac agattaaaga ctttctgaat ggaccagcgg atgtcaattt ggatatatca     6180

aagcctttga aagcaaacct gagtttcacc aaactggatc agataaacct ttttttaaag     6240

aagataaaaa atgcacacag tttggcacat agtgaagaga cttcagccat gtccaacacc     6300

atggtgaata aggatgatct tccagtctcc aaatattacc gtggaaagtt gtctaaaccc     6360

aaaattcatg gtgatggagt gcaaaagatt tcagctcaag aaaacatgtg gagagctgtt     6420

tcctgctttc aaaaaatttc tgttcaaact actcagattg tgatctccat ggaaactgta     6480

ccccatacca gcaaaccatg cctgttagca tctctctcaa acctcaatgg aagccttagt     6540

gtcaaggcaa cacaaaaagt acctggcata attcttgggt catcatttct actcagtata     6600

aacgattttc tccttaaaac aagtctcaaa gaaagaagcc gcattctgat aggaccatgt     6660

tgtgctactg ccaatctgga agctaagtgg tgtaaacaca gcgggaatcc aggcccagaa     6720

caatccatac caaaaatatc cattgactta agaggaggtc tactacaggt cttctggggt     6780

caagaacatt tgaattgttt agttcttcta catgaattac tcaatggata ccttaatgag     6840

gagggaaatt ttgaagtaca agtttctgaa ccagtgcctc aaatgtcatc tcctgtggaa     6900

aagaatcaga catttaaaag tgaacaaagt tcagatgacc tacggacagg tctatttcag     6960

tatgtacagg atgctgaatc tttgaaattg cctggggtct atgaagtctt attttataat     7020

gaaactgaag attgcccagg gatgatgtta tggagatatc cagaacctag agtactcacc     7080

cttgtacgaa taactcctgt accttttaac accacagagg atccagatat tagcacagca     7140

gaccttggtg atgtgctaca ggttccttgt agcttggaat actgggatga actccagaag     7200

gtttttgttg catttagaga atttaatctg tctgaaagca aagtttgtga actgcagttg     7260

ccggatatca atctcgtgaa tgaccagaag aaattagtat cttcagatct ttggagaatt     7320

gtcttgaaca gcagtcaaaa tggagctgat gaccaaagct ctgcaagtga gtctggttct     7380

caaagcactt gtgatccact tgtgactcca acagccctgg ctgcctgtac cagagttgac     7440

tcctgcttta ccccatggtt tgtcccatcc ctttgcgttt ctttccagtt tgctcacctg     7500

gaattccatc tttgtcatca ccttgaccaa ctaggcacag ctgcaccaca gtacctacag     7560

ccatttgttt ccgacagaaa tatgccatct gaactagaat acatgattgt ttccttcaga     7620

gaaccacaca tgtatcttcg acagtggaat aatggttctg tctgtcagga gatccagttc     7680

ttagctcaag cagactgtaa acttctagag tgcagaaatg tcactatgca aagtgtggtg     7740

aaacccttca gcatcttcgg gcagatggca gtttccagcg atgtagtgga aaagctgctt     7800

gactgcaccg tgatagttga ttctgtattt gtaaaccttg gacagcatgt agtccattca     7860

ctaaacactg caatacaagc ttggcaacag aacaaatgcc ctgaggtaga ggagttggtc     7920

ttcagccatt ttgtgatctg taatgacaca caggagacac tgcggtttgg ccaggtggat     7980

actgatgaaa atattctgct ggcgagtctc cacagtcacc agtacagctg gcgctctcac     8040

aaatccccac agctgttaca catctgtatt gaaggttggg gcaactggcg ttggtcagag     8100

cctttcagtg tggaccatgc cgggactttt attagaacaa ttcagtacag gggtcgaact     8160

gcttctctca tcatcaaggt tcagcaactc aatggagtac aaaaacagat tatcatctgt     8220

ggaagacaga tcatctgtag ttacttgtct caaagcatag aactaaaagt cgttcagcat     8280

tacattggtc aagatggaca agctgtagtt cgggaacatt ttgactgcct cacagccaaa     8340

cagaaattgc cttcgtacat actagaaaac aatgaactga cggagctgtg tgtgaaggcc     8400

aaaggagatg aagactggtc aagagatgtg tgcctggaat ccaaagcccc tgagtacagc     8460

attgtcattc aggtgccatc ttcaaacagt tccattattt atgtctggtg cacagttttg     8520

actttagaac ccaactctca agtgcaacaa cgaatgattg tgttcagccc tctttttatc     8580

atgaggagtc atcttccaga ccccattatc atacatttgg agaaaaggag tctgggattg     8640

agtgaaacac aaattattcc aggaaaaggg caggaaaaac cactgcaaaa catagaacct     8700

gaccttgtac atcacctgac attccaagca agagaagaat atgatccttc agattgtgca     8760

gttcccatct caacatccct cattaagcaa atagccacta aggtacaccc tggaggcaca     8820

gttaatcaga tccttgacga attctatggg ccagaaaagt cgcttcaacc catatggccc     8880

tataataaga aggattctga caggaatgaa cagctaagtc agtgggatag cccaatgcga     8940

gtgaagctgt caatctggaa gccatatgtt agaactttgt tgatagaact tctgccctgg     9000

gccctgctta tcaatgaatc caaatgggac ctctggctat ttgaaggaga gaaaattgtt     9060

ctacaggttc ctgctggcaa aattattatt cctcctaatt ttcaggaagc ttttcaaatt     9120

ggaatatact gggcaaatac aaacactgtg cacaagtcag tagcaattaa actggtccat     9180

aacctgacat ctccaaagtg gaaagatgga ggtaatggtg aagttgtgac actggatgaa     9240

gaagcgtttg ttgatactga aataagactt ggtgcttttc caggacatca gaagttatgt     9300

cagttctgca tttcctccat ggtacagcaa ggtatacaaa ttattcagat tgaagacaag     9360

actacaataa tcaataatac accatatcaa atattttata aaccacagct atctgtctgc     9420

aatccccatt ctggaaagga gtattttcgt gttccagaca gtgctacttt tagcatttgc     9480

ccaggtggag agcagcctgc tatgaaatcc agctcccttc cttgctggga cttgatgcct     9540

gacatcagtc agtcagtact ggatgcatcc ctgcttcaga aacagatcat gctgggcttt     9600

tctcctgccc caggtgctga cagctcacag tgctggagcc tgccagctat agttagacca     9660

gagtttccca gacagagtgt ggcagtaccc ctcgggaatt tccgggaaaa tggattctgt     9720

accagggcta tagtgctgac atatcaagaa cacctcggag tgacttattt aaccctctca     9780

gaagacccta gtcctcgagt aattatccac aatagatgtc cagtaaaaat gcttataaag     9840

gaaaacatta aagatattcc aaagtttgag gtttattgca aaaaaattcc ctccgagtgc     9900

tcaattcatc atgagctgta tcatcagatt tccagttatc cggactgcaa gaccaaagac     9960

ttacttccaa gcctactttt gagagttgaa cctctagatg aagtaacaac tgagtggagt    10020

gatgccattg acatcaacag tcagggaaca caggttgtgt tcctgactgg ctttggctat    10080

gtgtatgtgg atgttgtaca tcagtgtggc acagtcttca tcactgtggc cccagaagga    10140

aaagcaggac ctattttaac caataccaac agagcgccag agaagattgt tacatttaaa    10200

atgttcatca ctcagttaag cctggcagtg tttgatgacc tcacccacca caaagcatca    10260

gctgagcttc tgagactcac actggacaac atttttctct gtgtggcccc gggagctggt    10320

cccctccctg gggaagagcc tgtggctgcg ttgtttgaac tttactgtgt ggagatctgc    10380

tgtggggacc tgcagctaga caaccagctt tataacaagt ccaatttcca ctttgctgtc    10440

ttagtctgcc agggagaaaa agcagaaccc attcagtgtt ccaaaatgca gagtctcctc    10500

atatccaaca aagagttgga agaatacaag gaaaaatgtt ttatcaaact ttgcatcacc    10560

ttaaatgaag gcaagagcat cctctgtgat attaatgagt tcagctttga attaaaacct    10620

gctcggttat acgtggaaga cacatttgta tactacatca agactttgtt tgacacctac    10680

cttcctaaca gcaggttggc tggtcactcc acacacctct ccgggggtaa acaggtgttg    10740

cccatgcagg tcacacagca cgccagggcc ttggtgaatc ctgtgaagtt acggaaactg    10800

gtgatccagc cagtaaattt gctcgtcagc atccacgctt ccctcaagct gtacatagcc    10860

tcagaccaca ctcctctctc cttctcggtg tttgaaagag gacccatctt caccactgcg    10920

aggcagcttg tgcacgccct ggcaatgcac tatgccgctg gggccctttt tagagcaggc    10980

tgggtagttg ggtctctgga tattcttggc agccctgcaa gcctggtgag aagcatcggg    11040

aacggggtcg ccgacttctt caggcttccg tatgaggggc tgacccgggg ccctggagcc    11100

ttcgtgagtg gcgtctccag agggaccaca tcgtttgtaa agcacatctc caaaggtacc    11160

ctcacatcca tcaccaacct cgccacaagc ctggcccgga acatggaccg gctctcactg    11220

gatgaggagc actacaaccg gcaggaggag tggcggcggc agctccccga gagcctgggc    11280

gaggggcttc gacagggcct gtcccggctg ggcatcagcc tgcttggtgc aattgctggt    11340

atagttgatc agccgatgca gaacttccag aaaacatctg aggcacaggc ttcagcagga    11400

cacaaggcca agggtgtcat ctcgggtgtg gggaaaggaa tcatgggggt gttcacaaag    11460

cccatcggag gagctgctga gctggtgtca cagactggct atggtatttt acatggagct    11520

ggactttctc agcttcccaa acagcgccat cagccaagtg atctacatgc tgaccaggct    11580

ccaaacagcc atgtcaaata tgtctggaaa atgcttcagt ctctgggcag accagaagtc    11640

cacatggccc tggacgtggt tctggtgagg ggctcaggcc aggagcatga agggtgcttg    11700

ctgctgacat cagaagtgct cttcgtggtg agtgtcagtg aggacacaca gcagcaggcc    11760

ttccccgtca cagaaatcga ctgtgcacag gacagcaagc agaacaactt actcacagtg    11820

cagctcaagc agccaagagt ggcctgtgat gtggaggtag atggagtccg agagagactg    11880

tcagagcaac agtacaacag actggtggac tacatcacaa agacatcttg tcacctggcc    11940

cccagctgtt cttccatgca aataccatgc cctgtggtgg ctgcagaacc tcccccctcc    12000

actgttaaaa cataccatta cctggttgat ccacattttg ctcaggtctt ccttagtaaa    12060

tttaccatgg tgaaaaataa agccctgagg aaagggtttc cttgagtccc ctctgaggtg    12120

tttattcctg cttgtgtgat ttagtttttg ggtttctttg agacagggtc tcactgcatt    12180

gcccttgctg acctcaaatt ctggggttca agcaatcctc ccacctcaac ccacaagtag    12240

ctacgactgc aagcacctgc caccataaag ggctgcattt tgccaccata aagggctgca    12300

tttttttaaa aagcctaggc agctctaaca tcatctgata tggacacaag gccaacagtt    12360

tccttattta catccttacc tctaaaagat acttcaaagt gacaaaaacg tgttccttcc    12420

ccacttagag acaatgatta acagggccct atatgttctt accacataca gaggatgcat    12480

ttatttttgc tctatgacac ttgcaaaaat ctctactgta attaatttgg gtctattatt    12540

aactctctgt tccatcatag aatgtggcca ggccttacaa tggagagcca gagttaaaac    12600

ttcaagttgc atctgttttt gggctgagtc accacctttg cctcatgctc ctttgtctgc    12660

aaaggcctag gattctttct ttaaatgaaa tgcttaggac tttgtggctt gttacatttg    12720

tcatttaact gcagtgctat tctttgaaag ctgctatgtg tattttctct gaagtctgca    12780

ttttactaaa atttacaaca gtctgatgat tgattgatta ctgtccaggt acattttaga    12840

aaaagtgttc ttcttccagt ttgttttact aagcaaactt tgagtaaatc ctttgtccta    12900

tattgaatcc agtcccaaag tgttcaggtg agtttctcta gttccataaa caaaacatac    12960

atagtgggaa ctccctggta tgccatagag cacacaagaa ccccaatatt aatgctaaca    13020

attataccag tccattttgt ttattctgtg gaattgactt gacaaagcat gaagatattc    13080

ccagtgtctg tctgataata ttttgcatct aagaatgggt ttgactcaag atcttgggtt    13140

accaagatgt cttaaatgtt cagtaaatat ctttcttaca gtccagtagc ttagagcatg    13200

tttgctgatt gatattacat ttaaacttgg ggctacagct tgttacctag aattttgaga    13260

tactaagaga atgcaatttt aaatgcccac tggttttatt tgttttggag agagggtctc    13320

attctgtcac ccaggctaga gtacagtggg aacagtcatg gctcactgca gcttaagctc    13380

actgcctggg ctcaagtgat cttactccag cctcccaagc agctgggact acaccaccac    13440

aggtatgcac caccatacct ggctgatttt taaaattttt tctagagatg aggtctcact    13500

atgttgccca gctggtctca tactcctcag ttcacgcatt cctcccacct ccacctccca    13560

aactgctggg attacaggtg tgagccacca tgcccaacac ccactgatct ttaactctca    13620

catgttgggc ataagaagtc actatataat tgttactgga aagcaagact taacgaacaa    13680

ttctgactat gaaaaatgtc tctttcagtt tgttctgtaa atatttagaa aagtgacagc    13740

tgtcaacctc agagtaacta tttctaaaaa tgtaaatatg tattaatcct tgtatctttt    13800

atggtaattt tgcatattga tatgaattat ataaaattgt ttaaaataaa aggtgtcctt    13860

gaattactga ccacccatag atgtctactg ttaccaggtt ttacaatgca aattttcact    13920

aatacctggg tttaatacag ctcacatcac tgaatgttac acatgagttt aaatgggtaa    13980

tatacaggtt ttgttataat aaagttactg attaaattag ctttg                    14025


<210>  2507
<211>  1632
<212>  DNA
<213>  homo sapiens

<400>  2507
gctcagcatt tggggacgct ctcagctctc ggcgcacggc ccaggtaagc ggggcgcgcc       60

ctgcccgccc gcgatgggcc gccagctagc ggggtgtgga gacgctggga agaaggcttc      120

cttcaaaatg tctactgttc acgaaatcct gtgcaagctc agcttggagg gtgatcactc      180

tacaccccca agtgcatatg ggtctgtcaa agcctatact aactttgatg ctgagcggga      240

tgctttgaac attgaaacag ccatcaagac caaaggtgtg gatgaggtca ccattgtcaa      300

cattttgacc aaccgcagca atgcacagag acaggatatt gccttcgcct accagagaag      360

gaccaaaaag gaacttgcat cagcactgaa gtcagcctta tctggccacc tggagacggt      420

gattttgggc ctattgaaga cacctgctca gtatgacgct tctgagctaa aagcttccat      480

gaaggggctg ggaaccgacg aggactctct cattgagatc atctgctcca gaaccaacca      540

ggagctgcag gaaattaaca gagtctacaa ggaaatgtac aagactgatc tggagaagga      600

cattatttcg gacacatctg gtgacttccg caagctgatg gttgccctgg caaagggtag      660

aagagcagag gatggctctg tcattgatta tgaactgatt gaccaagatg ctcgggatct      720

ctatgacgct ggagtgaaga ggaaaggaac tgatgttccc aagtggatca gcatcatgac      780

cgagcggagc gtgccccacc tccagaaagt atttgatagg tacaagagtt acagccctta      840

tgacatgttg gaaagcatca ggaaagaggt taaaggagac ctggaaaatg ctttcctgaa      900

cctggttcag tgcattcaga acaagcccct gtattttgct gatcggctgt atgactccat      960

gaagggcaag gggacgcgag ataaggtcct gatcagaatc atggtctccc gcagtgaagt     1020

ggacatgttg aaaattaggt ctgaattcaa gagaaagtac ggcaagtccc tgtactatta     1080

tatccagcaa gacactaagg gcgactacca gaaagcgctg ctgtacctgt gtggtggaga     1140

tgactgaagc ccgacacggc ctgagcgtcc agaaatggtg ctcaccatgc ttccagctaa     1200

caggtctaga aaaccagctt gcgaataaca gtccccgtgg ccatccctgt gagggtgacg     1260

ttagcattac ccccaacctc attttagttg cctaagcatt gcctggcctt cctgtctagt     1320

ctctcctgta agccaaagaa atgaacattc caaggagttg gaagtgaagt ctatgatgtg     1380

aaacactttg cctcctgtgt actgtgtcat aaacagatga ataaactgaa tttgtacttt     1440

agaaacacgt actttgtggc cctgctttca actgaattgt ttgaaaatta aacgtgcttg     1500

gggttcagct ggtgaggctg tccctgtagg aagaaagctc tgggactgag ctgtacagta     1560

tggttgcccc tatccaagtg tcgctattta agttaaattt aaatgaaata aaataaaata     1620

aaatcaaaaa aa                                                         1632


<210>  2508
<211>  2099
<212>  DNA
<213>  homo sapiens

<400>  2508
gcggccgccg ggcgccggag ccgcgtcccc ctgcgccgcc ccgggcctgc cggccggagg       60

agccaccata caccccgggt cgccgagcgc ctggccgccc cgcgcccgcg ccgcgctccg      120

cctgtggctg ggctgcgtct gcttcgcgct ggtgcaggcg gacagtccct cagccccagt      180

gaacgtcacc gtcaggcacc tcaaggccaa ctctgcagtg gtgagctggg atgttctgga      240

ggatgaggtt gtcatcggat ttgccatctc ccagcagaag aaggatgtgc ggatgctgcg      300

cttcatccag gaggtgaaca ccaccacccg ctcatgtgcc ctctgggacc tggaggagga      360

tacggagtac atagtccacg tgcaggccat ctccattcag ggccagagcc cagccagcga      420

gcctgtgctc ttcaagaccc cgcgtgaggc tgagaagatg gcctccaaga acaaagatga      480

ggtaaccatg aaagagatgg ggaggaacca acagctgcgg acaggcgagg tgctgatcat      540

cgtcgtggtc ctgttcatgt gggcaggtgt cattgccctc ttctgccgcc agtatgacat      600

cattgaagcg tgactgcctg tctgcaggga gaaggattcc atttttcttc tcagctggtc      660

cccaggccca cgggcacagg gagagggaca actgcagcag tggggaggag gcacagctag      720

ctgcacagtt ctctcttctc cttgtcctag tcagatgaag gaggctgcac tacaaaccca      780

aattctgcaa aaaaataaaa ataagccaca aaactaaaag gcctggcccc attctggaaa      840

aggcaaagct gcatgagaca cagccttctg cctcctcgcc tctcctggac tggcttcctc      900

tttgagaaaa tgcacaaagc cctgggagat gacaagcaca aggactgact caagctgtgt      960

ctttcagacc aaggaacatc agagaagctg tggggctgcc tgccaggcag gatcatggct     1020

gccatcaagc cttttctgga tccagccatc aaggacatgt ttgtggtgtg atgcacactt     1080

ttgcaagcgt gtaagatgtt acctggtttg tctcttttgg aaaacaaaaa tcagaaggct     1140

gcattctaga gggcagagaa attcccccga agactgagct ggttgcctgc atcctctatc     1200

ttctttgacc cttatgactg aaagatcatc agtttggaag gtactggtcc aatttattta     1260

ggaagtatct cttggagttt cagaaatgct agcttggaca actgaaaagt cacatcacag     1320

ctggcattct gggggctacc aaaacacccc ttctggagta gaagctgctg gaaggcaggc     1380

ctgagccatt caccacggac aggaagagca gctctggcta tcaccactgg cctctggggt     1440

cttcatatct tgccatctca tccagggttc catgaaagtt acccagggtc ctcatgtcct     1500

tccttagagc ctgagtggtg tgaggtgaca ggtctctctc tccactgccc ctttctggtt     1560

taaaaaaatg gtgcttgatg agggaaggta gactcttccc taggactgac gagttacggc     1620

tgccagatgc ctgcatggga agaggtggac atctgcatct tccattggtg gtcaaggatg     1680

ggtgtgggag aaccacacct agtgcaagcc tggtactcag taaatatttg ttgaaatgaa     1740

tgataagagc attggtcccc aagccagaga gccagaagcc atcacccaat gaccgcccct     1800

tccttccggt ctacaagagc tctcaaggct gggtctgcca ccactctgct ttgcccaagt     1860

gtgacagcac tggggaggag agacaggata aagggcagat gtcagcaata ctaagggctt     1920

cctcatggga gggcatgagg ctccactcat tgtcttgtga cttccatccc tgctgaatgg     1980

ggctgcaagg ccaaggctcc ttaggggaga ggtccttacc tctgatccac ttagagcaat     2040

aaccactttt taaatgtaaa ataaaaagac aaatgaaaag gcaaaaaaaa aaaaaaaaa      2099


<210>  2509
<211>  6900
<212>  DNA
<213>  homo sapiens

<400>  2509
agcgcaggtc ccgacagagg tcgccgggtg gtggcgtcag ctgcggcgcc ctccgcgtgg       60

aaattagccg gttgcccggg caaatcaggg aggaagggag ggagctgaac acggaagtgg      120

tggcggcgcc cagggaaccg gcggaggcga tgaccgtgac ggctgggttg ggaccggaac      180

gccgaagcgg ggttgggggt ggcagaaaag catctgcttt gtaagaccta cacgaggtgc      240

aggagtggtt gggcctcccc tctccactta agcaagcgcc cagactgatg gcgatggtga      300

tggcagcagt tactcgcaca accccagtta agctgcgctc cgggagatac atccagaaag      360

tgcccagaag aaacttcctg ctggaaaaaa tgaaaaagca gtatttataa cattagaatc      420

tggataattt gttaacatgg cagaaaataa tgaaaatatt agtaaaaatg tagatgtaag      480

gcccaaaact agtcggagca gaagtgccga cagaaaagac ggttatgtgt ggagtggaaa      540

gaagttatct tggtcaaaaa agagtgagag ttattcagat gctgagacag tgaatggtat      600

agagaaaacc gaagtgtctt taaggaacca agaaaggaag cacagctgtt catccattga      660

gttggactta gatcattcct gtgggcatcg atttttaggc cgatctctta aacagaaact      720

gcaagatgcc gtggggcagt gttttccaat aaagaattgt agtagtcggc actcttcagg      780

gcttccgtct aaaaggaaaa ttcatatcag tgaactcatg ttagataagt gtcctttccc      840

acctcgatca gatttagcct ttaggtggca ttttattaaa cgacacactg ctcctataaa      900

ttccaaatca gatgaatggg taagcacaga cttgtctcag actgaattga gggatggtca      960

gctaaaacga agaaatatgg aagaaaatat aaactgtttc tcacatacca atgttcagcc     1020

ctgtgtcata accaccgaca atgctttgtg tagagaaggt cctatgactg gctctgtgat     1080

gaacctggtt tcaaataaca gtatagaaga tagtgatatg gattccgatg atgaaattct     1140

aacactttgc acaagttcca gaaaaagaaa caaacccaaa tgggatttgg atgatgaaat     1200

cctgcagttg gaaacacctc ctaaatacca cacgcagatt gattatgtcc actgtcttgt     1260

accagacctc cttcagatca ataacaaccc atgttactgg ggagtgatgg ataaatacgc     1320

agccgaagca ctactggaag gaaaaccaga gggtaccttt ttacttcgag actcagcaca     1380

ggaagactat ttattctctg ttagttttag acgctatagt cgttctcttc atgctagaat     1440

tgaacagtgg aatcacaact ttagctttga tgcacatgac ccctgtgtct tccattctcc     1500

tgacattact gggctcctag aacattataa ggacccaagc gcctgtatgt tctttgaacc     1560

acttctatcc actcccttaa ttcggacttt ccctttttcc ctgcagcata tatgcagaac     1620

agttatttgt aactgtacaa cttatgatgg catcgatgcc cttccaattc cttcttctat     1680

gaaattatat ctgaaggaat atcattataa atcaaaagtt agagtactca ggattgatgc     1740

accagaacag caatgctagt aacaggatgg gaacatggga atgataatat atattttttc     1800

ttttaatatt ttatttttct ttttatgcca ctttggattt ttctacaaag gcagtggtgt     1860

ccaaaataaa atctctgccc taaattttac taataaatcc atttttctag tgatacacaa     1920

attgtttaag gttatacact cgagcttaaa tagatatttt taaccaggtg tttggttttt     1980

gtttttaccg tgtaggttgt atacttacat tttttctttc cttaatttat acatgatcct     2040

ttttccttaa tttatacatg atccaggcac atttgaaatt tggtaggcat tgcaaacaca     2100

tttgaatatt gtgtatttca tactattctt taaaagtaat cttatgtcct ttcctacatg     2160

taaaatattt tgttaatcta tgccattagt agtattatat ataaaatata gttccccgtc     2220

ccccttttca ttgagtttga tattcttcag taaagctgaa tgttgtaatt caccattcat     2280

actaatgtta ttgacttttg taacttacta atagggatgt taaaagtaac aaaaccaagt     2340

caaacttggt gtatttttat tttaaatatt aactctaaag caggattact aaatttgatt     2400

aatctggtca atgagaatca aatggaaaca tatcattctg gaggtgcact tactcttcta     2460

caatgtggcc ggatcatttg tcattcctga ataggtcttt ctctcaacct gcaagagcta     2520

aaccatcttc aaaacataaa tcttgttcct ttctcattgg aagctttgaa aataatgata     2580

acactattag tagctagtag ttactaaagt gctaaagtaa ttgtggggtt tttctgtatt     2640

agcttatgaa ctgttgcttc tacttagccc ttttatagaa actctgagct gttactttgg     2700

ggaaattcca caatgtatta gcagccacaa atttccactg gtaaccaaag agtacctaag     2760

tagtttttca ttattttaag ttgaatttga ataaagattc cagaaataaa catggagctc     2820

agtattcagg aagcttaata ctgtttttga tctacaagat ccaaataatt atccctatct     2880

tcagaattaa cttagtctgt aatgtggctt caaaaaaaga aagccttttg acagctacat     2940

gacttacacc atacagaaca gtactggaca aaaggggtga tattttaaat ttactatccc     3000

agaaacaggg caacgttttt agaaacatct ttagcccaaa gtaactagta aaaataaatg     3060

gagtggtatc ctatcttctt tttttaagga atcaatgaat aataaatgta gatagacaat     3120

tttcttctgg tgagctgtct aaccctttgt acacattgac atttttaata tcgtaactga     3180

tttcttgatg ctagtttagc tatattagga aactgcttct acctagattg aaagaaattt     3240

gactcataaa cttccaagtt agaacaaata tttcttcatt attgttgctt ttatgtgagt     3300

agcatttccc tatcttgcag ttctgttaac atgaaaatgg catttttcca taatagcttt     3360

aaaataattt tttagtaatt attacaaaat taaggaaaat ctctattacc gttatctttt     3420

agcatttttt ttttcctcag tgatctcaag attgtcttag tctcaatgag atgtagctac     3480

aaaaatggca cctcttagca gtgatgaggc tcaggatatc ggatatcata acaccaatgt     3540

caggataaat atctcttcta aagacgatat ttacctttta caaggttaga aaagtctcat     3600

actacctcat ctttattgtg gcgcttttgt agatcactga gaagcttatc ttattaacca     3660

atataccact tcctaaatat ccatctttgg tgaaagaaaa tagtgtggta agagtaccca     3720

tgattatagt tttttatcag aatttgataa gattttctgt ttctgtgaaa caattatttt     3780

aaatattttt cttttaaaaa taacttttta tcagtacaga aaaacctaag ggatgactag     3840

cttacaaata ttctgttaag gggtagtttt ataaagaaaa atgatatata gttatgttgt     3900

cttttatagt gttaaaatta gtatttatat gaaagtcaag atctaagtac cttttcatat     3960

aattcaaact gattgcttgt gatatgtttt ctctggcttt tttatttttt caacttcaag     4020

gtattaacag ctgttaacac ttaaaaagta ctgccacata tgtagccttg aagtagttga     4080

tctaataaat gagagcaggg aggagattca ttgactctga aatgattttt atttttcctt     4140

tggtatttgc tacagtgaaa agaagtttgg aaagtagata cataaagact tgagaaggga     4200

attgtttaag ggaaaagaaa agagtaataa ttttttttaa aacattaagg aattggaatt     4260

cagaaaggtt acccccttcc tctgtgtctt tgtaaggata catttggaag aacatacagt     4320

attcagaaac taacctatat aaaatgtaaa caatatattg attgcactat ataaatgagt     4380

aaattttgag aggaacaatg tgggaatgta taaatttgtc taaaatttta taactgttga     4440

acaaagggaa gatttgaaca gtgtaaattc cagagttgag aaagcattta gcatggtgga     4500

aatgtggaga gcttattggt gagagaggat ggagctaaga gaaataagat caaatattaa     4560

aattaggaat ttaggcatta cctcagggaa aagccttgac agtgaaaaga aactacttaa     4620

tcgctaatag ctagtctgga ccagacactt aactgcgctt tgggaatcat cctgggctaa     4680

tcaggaaata aacttgactt ttctattttt ctctgaagct ttacaggaca tactcccact     4740

cccatttttt tctaagccta cagcatcttg attcatagta taattcctga agtatgctga     4800

atggactttt taaggttcct ttagcatttt tgtatagagt tatatgtgat ctttctataa     4860

ccatgccatt cacttaaata attcatgaag ggaatggttt aatttaaagg aagacctaat     4920

aggaagaaga ttaaaggaag cttttagtca gcctgtggct agatttattg atttggtgat     4980

caaacctgtg ctatttcctg aatttcagct aatggccaac tgtggtcaaa gaatggcttt     5040

cagttaaagt tttgacttct tattataaat aatataaaga atgtctcagt aattagaaat     5100

cccttaataa gtagaacaaa tgtggcaagt aggactccta tcggtataca aattccattt     5160

ctttttataa gaaaaacaca taaaccatta tcatttattc atgagccaaa gccattaaga     5220

agataaatcc agttatcagc ttcctgtctc tgaagtttgg atcattttat agatccacgc     5280

aatagagagc ttccttccta tgaaacaaaa accttgagat ctcttttttt ttgagacaga     5340

gtctcgctgt tgtcagccca ggctggagtg caatggcgca atctcggttc actgcaacct     5400

ctgccttcca ggttccagca attctcctac ctcagctccc aagtagctga gatgacaggc     5460

gtgtgccacc acgcccagct aatttttgta tttttagtag cgatggtgtt tcactacatt     5520

ggccaggctg gtctcgaact cctgacctca ggtgaccacc cgcctcagcc tcccaaagtg     5580

ctgggattac aggcatgagc cactgtgccc ggccaagatc taactcacgc ttacttttca     5640

ttaaaatatt tcttgtcgct tttagctatt gtcagaatcc aataaacagc ttacgcattc     5700

attttggtaa agcaaatttc acaggaaaat agacaaaatt ataagagatt cctggagaca     5760

acacaaggaa aacaatgttt aaaagcaaaa tagcctgtgt aatgttaggt aatgtaatgc     5820

ccaagtgaat aaaagatttt tcgtcaagca aactactgtt tctactttgg gggaaaaaag     5880

tcagttttac atttgtaatt taaggaaaga acagaaagca caaaggtttt tcttttcttt     5940

attaatggcc tactagaaat gagcagtgca agagtctacc tgtactattc taatacagta     6000

agatattgga cacaaaatgg aggtaacttt ttaaaataga ttggcttgga agttgaaatg     6060

tagattaatg gatataaccc aatagaaagg gattttcaaa taaaaccaaa gtctattttt     6120

ttatttactt tctaattttg aacagatgac tcagtcctaa atctttgcct ttatttccta     6180

taaaatgtag gtgatacttg taactcgact tcctggagtt aattcttcag caagaggtga     6240

ccctgggagc gtactttaaa ataattgctg tacagccatt gagtactaac atgatgatag     6300

gttttcaaaa tatctttgta gtggatgctg cataattaca ttcacttctc ttagactgta     6360

aaagactttc ttgacttgtt ttaacagtag agatagcagt acaatttgaa tttatggttt     6420

aggctctgca attagaggaa caattgcagt ttcctcctac ccttcatatg gtctgtgtaa     6480

aactgatgtt tgcttaactt attttaaaag ttgattacgt tttcagaaaa taaagataat     6540

cacttttgcc atggttataa tcaaatctaa gctttcagac ttgagagcca tggtgtaaaa     6600

ctcaaggagg tttatttaaa ttatgctgac tttgctagaa ttggataaat tctgtataag     6660

ccaagtatga gttcacatgt actcgaatat acagttttca caaagctatt actctcatca     6720

gtcaggcttg tatgatctat tccttaccac aaaagaagta gacaattgcc acttttattt     6780

ctaatcctta agttgaatgt ttcttcttgg atgtaagttc aaataaattg atctggataa     6840

attttcattt ctacttaatt aaaacttcct atgtaaaatc caaaaaaaaa aaaaaaaaaa     6900


<210>  2510
<211>  5852
<212>  DNA
<213>  homo sapiens

<400>  2510
gagctggctg agagcgagag catgcctgga ttcttctgag gcatcaggaa aagcgttttg       60

catatttttc attgcctttc tttttttttt ttttttttta acttttgcct cagaaagaca      120

gctccctttc agagcaggaa tttcccttca aggtagcagg agatgaacgc gtgctgctcc      180

aggattttac agaactgatt ctgcagcaaa gacaaatgtt gcctgtattt gccagatagt      240

ataaacagga gcaaaagttg cacagctaaa ccaggggctc attcccagga cagacatgca      300

gttatggatt ccgaaagaca agtcaaggac actgatgaca ttgaaagtcc taaacgcagt      360

atccgagaca gtggctacat cgactgctgg gattccgagc gcagcgactc cctctctcct      420

cctcgccacg gcagagatga ttccttcgac agcctggatt cctttggctc tcgctctcgg      480

cagacgcctt caccagatgt agtcctcagg ggaagcagcg atgggagagg aagcgactct      540

gaatccgact tgcctcatcg gaagctgcca gatgtgaaga aggatgacat gtctgcacgg      600

cggacttccc atggtgagcc gaaatcagca gtgcctttta accagtacct cccgaacaaa      660

agcaatcaga cggcctacgt ccccgcgcct ctgagaaaga agaaagcaga gagagaggaa      720

taccgcaaga gctggagtac cgccacctcc ccgctgggtg gggagaggcc cttcaggagc      780

accagcatgt ttgacatgcg gtgtgaggag gaggccgcgg tgcagccgca cagcagggcc      840

cgccaggagc agctgcagct gataaataac cagctgaggg aagaggacga caaatggcaa      900

gatgacctgg ctcgttggaa gagtcgtaga agaagtgttt ctcaggactt aatcaagaaa      960

gaggaagaaa ggaaaaaaat ggagaagtta ctggctggag aagatgggac aagtgaacga     1020

aggaaaagca tcaaaaccta cagagaaatt gttcaagaaa aagagcggag agagagagag     1080

ctgcatgaag catataagaa cgctcggtcc caggaggagg cagaggggat ccttcaacag     1140

tacattgaga ggttcaccat cagtgaggct gttctcgaac gcttggagat gccaaaaatt     1200

ctggaaagaa gccattcaac agagccaaat ttatcctcct tcctgaatga ccccaatccc     1260

atgaaatacc tgcggcaaca gtcactgcct ccacccaaat tcactgccac tgttgaaacc     1320

accattgctc gtgccagtgt tctggatacc agcatgtcag caggcagtgg gtctccaagc     1380

aaaactgtca ctcccaaagc agtgcctatg ctgacaccca agccttactc ccagcccaaa     1440

aattctcaag atgttctgaa gacctttaag gtagacggga aagtcagtgt gaatggagag     1500

acggttcata gagaggagga gaaggaaaga gagtgtccca cggtggcacc tgcccactcc     1560

ttaaccaaat cccagatgtt tgaaggtgtg gccagagtgc acgggtctcc actggagctg     1620

aaacaagaca acggtagcat cgagatcaac ataaagaagc caaactctgt tccccaagag     1680

ctcgcagcaa ccactgagaa aacggaaccg aatagtcaag aggacaagaa tgatggtgga     1740

aaatcaagaa aagggaatat agaacttgcc tcatcagaac cacagcattt tacaacaact     1800

gtgactcgat gcagcccgac cgtggccttt gtggaatttc cctccagccc ccagctgaag     1860

aatgatgtgt cggaagaaaa agaccagaag aaaccagaaa atgaaatgag tggaaaggtg     1920

gagttggtgc tgtcacaaaa ggtggtaaag ccaaaatctc cagaacccga agcaacgctg     1980

acatttccat ttctggacaa aatgcctgaa gccaaccaac tacatttgcc aaatctcaat     2040

tctcaagtgg attctccaag cagtgagaag tcacctgtta tgacaccttt taagttctgg     2100

gcatgggacc cagaagagga gcgcaggcga caggaaaaat ggcaacagga acaggaacgt     2160

ttgctccagg agagatacca gaaggagcag gacaagctga aagaagagtg ggaaaaggcc     2220

caaaaggagg tggaagagga agaacgcaga tactatgagg aggagcgtaa gataattgaa     2280

gacactgtgg ttccatttac tgtttcttca agttccgctg accagctgtc tacctcttcc     2340

tccatgactg aaggcagtgg gacaatgaat aagatagacc tgggaaactg tcaagatgaa     2400

aaacaagaca gaagatggaa gaaatcattc cagggagatg acagtgactt attgctgaag     2460

actagggaaa gtgatcgact ggaggagaag ggcagcctaa ctgaaggggc cttggctcat     2520

tctgggaacc ctgtatcaaa aggagtccat gaagaccatc agctggatac cgaggctggg     2580

gccccacact gtggaacaaa cccacagctt gctcaggatc catcccagaa tcagcagaca     2640

tcaaatccaa cgcacagttc agaagatgtg aagccaaaaa ccctcccgct ggataaaagc     2700

attaaccatc agatcgagtc tcccagtgaa aggcggaagt ctataagtgg aaagaagctg     2760

tgctcttcct gtgggcttcc tttgggtaaa ggagctgcaa tgatcatcga gaccctcaat     2820

ctctattttc acatccagtg tttcaggtgt ggaatttgta aaggccagct tggagatgca     2880

gtgagtggga cggatgttag gattcgaaat ggtctcctga actgtaatga ttgctacatg     2940

cgatccagaa gtgccgggca gcctacaaca ttgtgacacg gctttcaagc ttccggatca     3000

ctcaccattt ctttactgag agtgtcccct ggcaactgct taacaaaatc ccaagctcag     3060

gggcttctca gcatttacct aatttctgaa aggctcttct gaaaggtggt atctgttctt     3120

tcgtagcaca gtgtttatgt ttttcctgtt tattgttttg gttttttttt tttttttgca     3180

tttgcacagt atacacaaaa gaatatgggg ttgtaatgat cctgaatagc tcaaaaaagg     3240

ttttagcatg gtcaaacagg cttatggttt aaaatgtgtt attctcttct ttgggaatta     3300

gctaaatgat gcaataaacc tgttttgttt tagaatgtct aggaattaaa cactttatgt     3360

ttacagaatt gagctgcaga aagtgcaaga catgccaatt tgagacacac ggtcttctaa     3420

gactgaagga taaatttaat gcatttcaga aactaaacat cacagcaagc tctatctctg     3480

agctataatt tgtttttaat gcaaagacac tagtttgata atatatactg taatcctgaa     3540

acatttgtgt tacttacctt tggaggtaga aattatacca ataaattatt gcaccgttag     3600

tattagattc tgtgtacctt ggaagttatg tcattaatat aggctggttc atcaaataaa     3660

gcaaaacctt gcaatatcag ctagatttac actccgggac gttgcccaaa ggtaggaaga     3720

aagcagaggg aaatatttca gtcatcattt ccaaagtcat tatcaaaatc tgtgaggaag     3780

tttaatcttc caaagagtca atgtcagaca tcaggcctct gttgcctgct tctctcgagg     3840

cactagatta ggagtcttca ataagagact taacatgagg tatatggaag atgaggcacc     3900

gagataagtt catcattagg tgtgagcact gctcaccctt gctggcaagt tctccttaag     3960

ggcctgaagc acaggtgtcc aaagaaaagc gttaagtcca tcttaataga atctatgtgg     4020

tatatgatgt ggtcagcccc tggtctgtga tcagcaagaa cctacagcac agattatgcc     4080

ctgcccactt caatgaatac ctactctcct ccattctcca tcactttttt tgctatcaag     4140

aactccggac cttgcccatg gagaagttta gagaggaact cttgtggaga gctggtttat     4200

tttctgccct gtgcgacgag tttcagctgg ccaagaaagg agtcaagtta ttaaaaagca     4260

tcacaatgta gatctccagg ctggtttttt gttttttgtt gttaagactg gggaaagggg     4320

gactatttat tctgccttaa atcaatggca aataagtcaa gatgacattt tgtgaatgta     4380

gactatggat acactcctaa tagattgatg tagtcataaa agggggtcaa gtagatgttt     4440

ttctgttatg taagcaataa tttttccgtg tcttattgag tatggctagc gattatttat     4500

tacatgctag atgggttctt tgcatgtggg ttccatatag gtgcagaaat ttcctcagcc     4560

actggaggga tttcgaccat atttgtcatt tggatgagct gttattagat tgaaatctac     4620

acatcatttc attaaaaatt gtgccttaga aaacgcaaag ctgttgcaca tggcgataaa     4680

ttatggatgc agtacattga agagagatga agtcacttcc aagtttccaa gacttctcat     4740

ggaggtgttt gctgttttac aggaaaaaat aaaaataaaa aaagaaaaaa agaaaaaatt     4800

aaaaagaaaa attgttttga aaatgtacag atcaagtcca atattttgat tatccacctg     4860

catgttttat taaatatttt gataatgtgg atgtttacac tttgcatgat attagcagag     4920

taccactagt aatgcacaaa catgtacaat atggtcattc ataaccgatt tttatagaat     4980

actttttaca tgtgcaactc catccgttat gtaaggatta catgaatatt gcacattccc     5040

ttctggtttc acaaacccat ttatacatat ttcttagtga ggctcattgt acatgtattg     5100

aagctagaat cgagtcaaga aaaataaagc cccattctcc aactgcaaaa tgtgctttcc     5160

cataatgaac actagtcacc agcacagaat aatctccaac attttctaaa ttctaattgc     5220

caactgtttc tatttatatt tgatttatat ttcatttgga gtctgttaca tggcagctta     5280

ggcagactag atcttgtttt ttccaatgca gcataatgag tatgatctat ttcttttcaa     5340

ataatctttg agatcccagg aaaaaaaaaa tgctctgctc cattgagcta taatgtaaat     5400

gtgtttgttt aaaaaacagg tgaggcaagt gagtgattta ttgttcctga ggaagtatat     5460

ctgatttttt ttctcatact ccaaaagcta gtccctactc tttaataaaa ataatgggta     5520

actttttgtt tttcactagc gaacttccat gacatttcct ttctatgtag tgtgattaat     5580

gcaatacata ttatagttat ctatacacag tgtaagattt aacaaactga aatgatccac     5640

ctcatatgtg agtccgtcca aaagatgtta ctgctctggg tgggccagtg ttctatatcg     5700

gttatactaa ctttcattta aagtatttat tctaaaatgc ctctgagaaa cagtaaaaaa     5760

taaaaacaac aagttgtcta aaatgcaaca gcttttatag taaatgtaca tttataaata     5820

aaatactcaa atcaaaaaaa aaaaaaaaaa aa                                   5852


<210>  2511
<211>  6106
<212>  DNA
<213>  homo sapiens

<400>  2511
ggcgacggcg gcggccgtcc tcatcccggc gcttgagagg acgcggggct gcgcaaatgg       60

cttgtcccgc tctcggtctg gaagctcttc agcccctgca gcccgagccg ccccccgagc      120

ccgccttctc cgaggcgcag aagtggattg agcaagtaac tggcagaagt tttggtgata      180

aagattttcg gacaggttta gaaaatggaa tcctcctctg cgagttgctg aatgctataa      240

agccaggact tgttaaaaag atcaatagat tgcctacccc cattgcagga ctggacaata      300

ttatcttatt cttgagaggt tgtaaagagc tcggccttaa agaatctcaa ctttttgacc      360

cgagtgacct ccaggataca tccaacagag taacagtcaa gagccttgat tatagtagga      420

agctgaaaaa tgtattagtt accatttact ggctgggaaa agcagcaaac agctgcacat      480

cctacagcgg aacgacacta aacctgaagg agtttgaagg attgttggct cagatgcgaa      540

aggacactga tgacattgaa agtcctaaac gcagtatccg agacagtggc tacatcgact      600

gctgggattc cgagcgcagc gactccctct ctcctcctcg ccacggcaga gatgattcct      660

tcgacagcct ggattccttt ggctctcgct ctcggcagac gccttcacca gatgtagtcc      720

tcaggggaag cagcgatggg agaggaagcg actctgaatc cgacttgcct catcggaagc      780

tgccagatgt gaagaaggat gacatgtctg cacggcggac ttcccatggt gagccgaaat      840

cagcagtgcc ttttaaccag tacctcccga acaaaagcaa tcagacggcc tacgtccccg      900

cgcctctgag aaagaagaaa gcagagagag aggaataccg caagagctgg agtaccgcca      960

cctccccgct gggtggggag aggcccttca gatacggtcc gagaactcct gtgtctgatg     1020

acgcagagag caccagcatg tttgacatgc ggtgtgagga ggaggccgcg gtgcagccgc     1080

acagcagggc ccgccaggag cagctgcagc tgataaataa ccagctgagg gaagaggacg     1140

acaaatggca agatgacctg gctcgttgga agagtcgtag aagaagtgtt tctcaggact     1200

taatcaagaa agaggaagaa aggaaaaaaa tggagaagtt actggctgga gaagatggga     1260

caagtgaacg aaggaaaagc atcaaaacct acagagaaat tgttcaagaa aaagagcgga     1320

gagagagaga gctgcatgaa gcatataaga acgctcggtc ccaggaggag gcagagggga     1380

tccttcaaca gtacattgag aggttcacca tcagtgaggc tgttctcgaa cgcttggaga     1440

tgccaaaaat tctggaaaga agccattcaa cagagccaaa tttatcctcc ttcctgaatg     1500

accccaatcc catgaaatac ctgcggcaac agtcactgcc tccacccaaa ttcactgcca     1560

ctgttgaaac caccattgct cgtgccagtg ttctggatac cagcatgtca gcaggcagtg     1620

ggtctccaag caaaactgtc actcccaaag cagtgcctat gctgacaccc aagccttact     1680

cccagcccaa aaattctcaa gatgttctga agacctttaa ggtagacggg aaagtcagtg     1740

tgaatggaga gacggttcat agagaggagg agaaggaaag agagtgtccc acggtggcac     1800

ctgcccactc cttaaccaaa tcccagatgt ttgaaggtgt ggccagagtg cacgggtctc     1860

cactggagct gaaacaagac aacggtagca tcgagatcaa cataaagaag ccaaactctg     1920

ttccccaaga gctcgcagca accactgaga aaacggaacc gaatagtcaa gaggacaaga     1980

atgatggtgg aaaatcaaga aaagggaata tagaacttgc ctcatcagaa ccacagcatt     2040

ttacaacaac tgtgactcga tgcagcccga ccgtggcctt tgtggaattt ccctccagcc     2100

cccagctgaa gaatgatgtg tcggaagaaa aagaccagaa gaaaccagaa aatgaaatga     2160

gtggaaaggt ggagttggtg ctgtcacaaa aggtggtaaa gccaaaatct ccagaacccg     2220

aagcaacgct gacatttcca tttctggaca aaatgcctga agccaaccaa ctacatttgc     2280

caaatctcaa ttctcaagtg gattctccaa gcagtgagaa gtcacctgtt atgacacctc     2340

agtttaagtt ctgggcatgg gacccagaag aggagcgcag gcgacaggaa aaatggcaac     2400

aggaacagga acgtttgctc caggagagat accagaagga gcaggacaag ctgaaagaag     2460

agtgggaaaa ggcccaaaag gaggtggaag aggaagaacg cagatactat gaggaggagc     2520

gtaagataat tgaagacact gtggttccat ttactgtttc ttcaagttcc gctgaccagc     2580

tgtctacctc ttcctccatg actgaaggca gtgggacaat gaataagata gacctgggaa     2640

actgtcaaga tgaaaaacaa gacagaagat ggaagaaatc attccaggga gatgacagtg     2700

acttattgct gaagactagg gaaagtgatc gactggagga gaagggcagc ctaactgaag     2760

gggccttggc tcattctggg aaccctgtat caaaaggagt ccatgaagac catcagctgg     2820

ataccgaggc tggggcccca cactgtggaa caaacccaca gcttgctcag gatccatccc     2880

agaatcagca gacatcaaat ccaacgcaca gttcagaaga tgtgaagcca aaaaccctcc     2940

cgctggataa aagcattaac catcagatcg agtctcccag tgaaaggcgg aagtctataa     3000

gtggaaagaa gctgtgctct tcctgtgggc ttcctttggg taaaggagct gcaatgatca     3060

tcgagaccct caatctctat tttcacatcc agtgtttcag gtgtggaatt tgtaaaggcc     3120

agcttggaga tgcagtgagt gggacggatg ttaggattcg aaatggtctc ctgaactgta     3180

atgattgcta catgcgatcc agaagtgccg ggcagcctac aacattgtga cacggctttc     3240

aagcttccgg atcactcacc atttctttac tgagagtgtc ccctggcaac tgcttaacaa     3300

aatcccaagc tcaggggctt ctcagcattt acctaatttc tgaaaggctc ttctgaaagg     3360

tggtatctgt tctttcgtag cacagtgttt atgtttttcc tgtttattgt tttggttttt     3420

tttttttttt tgcatttgca cagtatacac aaaagaatat ggggttgtaa tgatcctgaa     3480

tagctcaaaa aaggttttag catggtcaaa caggcttatg gtttaaaatg tgttattctc     3540

ttctttggga attagctaaa tgatgcaata aacctgtttt gttttagaat gtctaggaat     3600

taaacacttt atgtttacag aattgagctg cagaaagtgc aagacatgcc aatttgagac     3660

acacggtctt ctaagactga aggataaatt taatgcattt cagaaactaa acatcacagc     3720

aagctctatc tctgagctat aatttgtttt taatgcaaag acactagttt gataatatat     3780

actgtaatcc tgaaacattt gtgttactta cctttggagg tagaaattat accaataaat     3840

tattgcaccg ttagtattag attctgtgta ccttggaagt tatgtcatta atataggctg     3900

gttcatcaaa taaagcaaaa ccttgcaata tcagctagat ttacactccg ggacgttgcc     3960

caaaggtagg aagaaagcag agggaaatat ttcagtcatc atttccaaag tcattatcaa     4020

aatctgtgag gaagtttaat cttccaaaga gtcaatgtca gacatcaggc ctctgttgcc     4080

tgcttctctc gaggcactag attaggagtc ttcaataaga gacttaacat gaggtatatg     4140

gaagatgagg caccgagata agttcatcat taggtgtgag cactgctcac ccttgctggc     4200

aagttctcct taagggcctg aagcacaggt gtccaaagaa aagcgttaag tccatcttaa     4260

tagaatctat gtggtatatg atgtggtcag cccctggtct gtgatcagca agaacctaca     4320

gcacagatta tgccctgccc acttcaatga atacctactc tcctccattc tccatcactt     4380

tttttgctat caagaactcc ggaccttgcc catggagaag tttagagagg aactcttgtg     4440

gagagctggt ttattttctg ccctgtgcga cgagtttcag ctggccaaga aaggagtcaa     4500

gttattaaaa agcatcacaa tgtagatctc caggctggtt ttttgttttt tgttgttaag     4560

actggggaaa gggggactat ttattctgcc ttaaatcaat ggcaaataag tcaagatgac     4620

attttgtgaa tgtagactat ggatacactc ctaatagatt gatgtagtca taaaaggggg     4680

tcaagtagat gtttttctgt tatgtaagca ataatttttc cgtgtcttat tgagtatggc     4740

tagcgattat ttattacatg ctagatgggt tctttgcatg tgggttccat ataggtgcag     4800

aaatttcctc agccactgga gggatttcga ccatatttgt catttggatg agctgttatt     4860

agattgaaat ctacacatca tttcattaaa aattgtgcct tagaaaacgc aaagctgttg     4920

cacatggcga taaattatgg atgcagtaca ttgaagagag atgaagtcac ttccaagttt     4980

ccaagacttc tcatggaggt gtttgctgtt ttacaggaaa aaataaaaat aaaaaaagaa     5040

aaaaagaaaa aattaaaaag aaaaattgtt ttgaaaatgt acagatcaag tccaatattt     5100

tgattatcca cctgcatgtt ttattaaata ttttgataat gtggatgttt acactttgca     5160

tgatattagc agagtaccac tagtaatgca caaacatgta caatatggtc attcataacc     5220

gatttttata gaatactttt tacatgtgca actccatccg ttatgtaagg attacatgaa     5280

tattgcacat tcccttctgg tttcacaaac ccatttatac atatttctta gtgaggctca     5340

ttgtacatgt attgaagcta gaatcgagtc aagaaaaata aagccccatt ctccaactgc     5400

aaaatgtgct ttcccataat gaacactagt caccagcaca gaataatctc caacattttc     5460

taaattctaa ttgccaactg tttctattta tatttgattt atatttcatt tggagtctgt     5520

tacatggcag cttaggcaga ctagatcttg ttttttccaa tgcagcataa tgagtatgat     5580

ctatttcttt tcaaataatc tttgagatcc caggaaaaaa aaaatgctct gctccattga     5640

gctataatgt aaatgtgttt gtttaaaaaa caggtgaggc aagtgagtga tttattgttc     5700

ctgaggaagt atatctgatt ttttttctca tactccaaaa gctagtccct actctttaat     5760

aaaaataatg ggtaactttt tgtttttcac tagcgaactt ccatgacatt tcctttctat     5820

gtagtgtgat taatgcaata catattatag ttatctatac acagtgtaag atttaacaaa     5880

ctgaaatgat ccacctcata tgtgagtccg tccaaaagat gttactgctc tgggtgggcc     5940

agtgttctat atcggttata ctaactttca tttaaagtat ttattctaaa atgcctctga     6000

gaaacagtaa aaaataaaaa caacaagttg tctaaaatgc aacagctttt atagtaaatg     6060

tacatttata aataaaatac tcaaatcaaa aaaaaaaaaa aaaaaa                    6106


<210>  2512
<211>  2960
<212>  DNA
<213>  homo sapiens

<400>  2512
gcagtaccca agcgagccat ttaacatggc ggaggatgtt tcctcagcgg ccccgagccc       60

gcggggctgt gcggatggta gggatgccga ccctactgag gagcagatgg cagaaacaga      120

gagaaacgac gaggagcagt tcgaatgcca ggaactgctc gagtgccagg tgcaggtggg      180

ggcccccgag gaggaggagg aggaggagga ggacgcgggc ctggtggccg aggccgaggc      240

cgtggctgcc ggctggatgc tcgatttcct ctgcctctct ctttgccgag ctttccgcga      300

cggccgctcc gaggacttcc gcaggacccg caacagcgca gaggctatta ttcatggact      360

atccagtcta acagcttgcc agttgagaac gatatacata tgtcagtttt tgacaagaat      420

tgcagcagga aaaacccttg atgcacagtt tgaaaatgat gaacgaatta cacccttgga      480

atcagccctg atgatttggg gttcaattga aaaggaacat gacaaacttc atgaagaaat      540

acagaattta attaaaattc aggctatagc tgtttgtatg gaaaatggca actttaaaga      600

agcagaagaa gtctttgaaa gaatatttgg tgatccaaat tctcatatgc ctttcaaaag      660

caaattgctt atgataatct ctcagaaaga tacatttcat tccttttttc aacacttcag      720

ctacaaccac atgatggaga aaattaagag ttatgtgaat tatgtgctaa gtgaaaaatc      780

atcaaccttt ctaatgaagg cagcggcaaa agtagtagaa agcaaaagga caagaacaat      840

aacttctcaa gataaaccta gtggtaatga tgttgaaatg gaaactgaag ctaatttgga      900

tacaagaaaa agtgttagtg acaaacagtc tgcggtaact gaatcctcag agggtacagt      960

atccttattg aggtctcaca agaatctttt cttatctaag ttgcaacatg gaacccagca     1020

acaagacctt aataagaaag aaagaagagt aggaactcct caaagtacaa aaaagaaaaa     1080

agaaagcaga agagccactg aaagcagaat acctgtttca aagagtcagc cggtaactcc     1140

tgaaaaacat cgagctagaa aaagacaggc atggctttgg gaagaagaca agaatttgag     1200

atctggcgtg aggaaatatg gagagggaaa ctggtctaaa atactgttgc attataaatt     1260

caacaaccgg acaagtgtca tgttaaaaga cagatggagg accatgaaga aactaaaact     1320

gatttcctca gacagcgaag actgattgtg tttgtaaaag cttgatgaaa ggacagttaa     1380

gtattttgat cactgcattt tgtttgaaac ttgtgtcatt gatgtaattt aaaacttttg     1440

tttaaagcat tacagtattt ttctgtgacc atcaattaat gagggtttgt gctaccagag     1500

ttaaagcata tgctatcatt gtattcttta agaaccttat tttgataaaa tgtaaatttg     1560

ttgaaccctg ccacatttag tatccccacc cccaaatcct gttccaatga aaaaattaaa     1620

acctgatacg aaaaaaaaaa aattccagtt aacctatttt gtgtctgtag gctgacctca     1680

accctgtaac gtaacccatt aaaatgaatt tctttttttt taagacagag tttctctctg     1740

ttgcccaggc tggagtgcag tggcgcaatt tcagctcact gcaacctctg cctcccaggt     1800

tcaagtgatt ctcctgcctc agcctcctga gtagctggga ttacaggcac acaccaccac     1860

gcccagctaa tttttgtatt tttagtagag gcggggtttc accatgctgg tcaggatgtt     1920

ctccaactcc tgacttcatg atccacccac ctcggcctcc caaagtgctg agattacaga     1980

cgtgagccac tgcgtcctgc ctaaaatgaa ttttctagat gattgaataa cagtagtcct     2040

ttgatagaag ataatgactt ggtttatggc cttaatatac tacttaatta cttaagatgt     2100

ttattaatag aatgataaat gtacagagta acctataagc atgacatact tttgctttca     2160

gtagtttcat gtaaagaaaa aaacttgaaa atagtaatac ctgagtaccc atgggaataa     2220

tagacactgg ggaggtaggg tggggagcgg gagcaagagc tgaaaaactt acctactggg     2280

gactgtgctc actacctggg tgacaggatc atacgtaccc caaacctcaa catcacacag     2340

tatactcagc taacaaacct gcccatgtgt ttcctgaatc taaaataaaa atcgaaataa     2400

tttttttaaa aaagaaaaag acaatagtat tacccatggg acaaaatttg tactattagc     2460

aagaatcatt ttgtgtctca tttagaaaca atttgacttt tgttccagtg tttaaacttt     2520

gacaaaaatg gttttgaata gatctttata acctgatgcc ataaatacaa gattctctga     2580

taccttcatt taatatatca atattgggcc taaaacagta ttctgtaaag cttaaattgg     2640

tattaactat gatcatcttg atgtctatga tagataataa acaaggtcat acatacctta     2700

ctaaacaatt ttggtttttc accaacattt tattctttaa aagatttaga ctaacagaat     2760

tatttagcat ttcgagtcat gtgctttatt tagcaagtga gtaaaaatat tggaatattg     2820

aagtatttgc ataaaaaatc aaatggtggt gttttgtaat ctctattgta tttcctatta     2880

aggtttcata tattactttc ccattgttcc tgaatttgtt atcctatata taaacagaaa     2940

catggatgag taccatatac                                                 2960


<210>  2513
<211>  4622
<212>  DNA
<213>  homo sapiens

<400>  2513
atacctacac cggctttttg tacgactgtt ggccctggag aacgatcctt tggtggcgag       60

ggcggggagg acgaaagcgc ccactgtgga ttggacagtg tcaaaaagag gggcggtccc      120

tactgaaggg gcggttgggc gacgaaggga agagtctttt cagcgctgag gactggcgct      180

gaggaggcgg cggtggctcc cggggcgttt gagcgggctc acccgagccc gcgggccaac      240

gcggatccag gcccgactgg cgggaccgcc ccggattccc cgcgggcctt cctagccgcc      300

atggaggacg gcgtctatga acccccagac ctgactccgg aggagcggat ggagctggag      360

aacatccggc ggcggaagca ggagctgctg gtggagattc agcgcctgcg ggaggagctc      420

agtgaagcca tgagcgaggt ggaggggctg gaggccaatg agggcagtaa gaccttgcaa      480

cggaaccgga agatggcaat gggcaggaag aagttcaaca tggaccccaa gaaggggatc      540

cagttcttgg tggagaatga actgctgcag aacacacccg aggagatcgc ccgcttcctg      600

tacaagggcg aggggctgaa caagacagcc atcggggact acctggggga gagggaagaa      660

ctgaacctgg cagtgctcca tgcttttgtg gatctgcatg agttcaccga cctcaatctg      720

gtgcaggccc tcaggcagtt tctatggagc tttcgcctac ccggagaggc ccagaaaatt      780

gaccggatga tggaggcctt cgcccagcga tactgcctgt gcaaccctgg ggttttccag      840

tccacagaca cgtgctatgt gctgtccttc gccgtcatca tgctcaacac cagtctccac      900

aatcccaatg tccgggacaa gccgggcctg gagcgctttg tggccatgaa ccggggcatc      960

aacgagggcg gggacctgcc tgaggagctg ctcaggaacc tgtacgacag catccgaaat     1020

gagcccttca agattcctga ggatgacggg aatgacctga cccacacctt cttcaacccg     1080

gaccgggagg gctggctcct gaagctgggg ggccgggtga agacgtggaa gcggcgctgg     1140

tttatcctca cagacaactg cctctactac tttgagtaca ccacggacaa ggagccccga     1200

ggaatcatcc ccctggagaa tctgagcatc cgagaggtgg acgacccccg gaaaccgaac     1260

tgctttgaac tttacatccc caacaacaag gggcagctca tcaaagcctg caaaactgag     1320

gcggacggcc gagtggtgga gggaaaccac atggtgtacc ggatctcggc ccccacgcag     1380

gaggagaagg acgagtggat caagtccatc caggcggctg tgagtgtgga ccccttctat     1440

gagatgctgg cagcgagaaa gaagcggatt tcagtcaaga agaagcagga gcagccctga     1500

ccccctgccc ccaactccat tatttattac ggagctgccc cgcctgggtg gccggacccc     1560

tgggccttgg ggctgtggat cctggttccc tgtttggaaa attcaccacc tctagctcct     1620

cactgttctt tgtaattaac acgctgttgg taatcttatt aattatttaa ccacttggcc     1680

tgctgacccc ctcatttctt ggggttgaca gagtcgaggt gctccgtgga gccagcctgt     1740

ttccctggac aggggcctgg acccgcctgt ctctgggtgc tgcctgggct gtcccggtgg     1800

gtctgttctg gtttcacccc gagcccagca ggagtggagt aaagggagaa ggttaatatg     1860

gtgggagtct ggagttggaa ttggccgggg acagagttta gaatgcaggg attcagggtc     1920

aaggtctagc attcattcta gaagttactt gacagccatc agccagttac gctacagcca     1980

tcagctagtt cccatcgttg ctttcatggg gcttgaggtc tttgaggggc aggagatgaa     2040

gctggtgagg ttgtgagctg ggccagggct ttgaggacaa cctggagctg gaagaacatg     2100

cgaccacctc agggagggtc agggaaggat gagtggggag gtggcccatg tcctgcaagg     2160

gccttgctga tgggatgtcc tgaagggctg ggcagcctta gatcgggcta agagggcagg     2220

actgtgggcc agtgccagag ccaggcttgt ctgttctcaa aggatcagcc tcctttggag     2280

gacattttgt gtcaaggata gggctgagga cctgcgttct gaacgtcttt cctgggattc     2340

ttgacagcca aagaaattcg aggatcgcct ctatgaaggt gaagtcttgg catgtggggt     2400

acccctgaat cctgggctaa ggtctgtgac cttttgccct ccagttgggg tatgtgtggt     2460

gtccccaaag aacaagggct cgtggatccc gagcagggtg cgatggcgga ttgggaggtc     2520

ccatgtcact ctcccatgcc cgcctttgaa gctgaggcgc tctttagtta acaaactaca     2580

agtcccagca gggaccggga cgcgggtggg agaggcgcct gtggccccga ggcgtgccgc     2640

gagttgtagt ccctcctgcc cgctgtgttc gcttttgagc tctccgatgg gatgcggcgc     2700

ttcggaattt cgggctttga tccctgtccc gcccttggcc acaggcacct gccggcctga     2760

aggcccccgc ggtgggggta ccctgcgccc ctccgcggga aggtggacta cagttatcgg     2820

caggctgtgc ggcgccaaag ccacggtgac ccagacccga ggtttttccg ggcgtcgcag     2880

tttcccgaga ctccgtggcg gcgtttgtct tctttttctt agtcagatcc cgtacttttg     2940

tggagggtag aggaggcttt gaccgccgcg gccccggggg ctggtgggaa atggagttcc     3000

aaatgagaaa atagaattcc ccacttctct ttcccacagg tgccagggaa acggagtcat     3060

cgacccaaga aggtcgtggg agatgaggtc ccagggtaaa cagcgggtcc cgccactatg     3120

tcaccctttc ctgccgcctc cccggatgaa ctgcatgcag ggcggccggc tccgtggcag     3180

gcagaggcag gaagaggcgc ggagcccgct ggtggcgaag aggggagtgc ggcgggaggg     3240

gagggcagag gcaggcggcc ggtcgcgtgg ggcctgggcc gccccaggag ggcctctggc     3300

tggattctta gcagatggaa gccgtgcaag ggcaggaggc aggggcctga cgtgtttgga     3360

ttgaggttgc aggaggggcc cctggctgct tcagggagaa taatttggag gcgagcgggg     3420

aggtgagagg aagctgtgcg gtgcaggatg gcgtggctgt ggaggtggag aacgttgggc     3480

cacgctagga gtcttgaaag aggagccaaa aggacttgct gagagccgcc gcagctggtg     3540

aatgacggtg ccatgactga ggtggtcgaa agggagtatt taaggggaaa tcaggcattc     3600

cgttttgacc aaattaagct ggagatgcct gtggaacatt ccagccaggc tgcatcacgt     3660

cacactgacc ttcagcattg cccacagtcc atcttccccc aggacctgag gattttgcgt     3720

ccggctccct cctcgcccag gacccccaag ctcccagcac gcttctgatt ttttttgtag     3780

gttttttttt ttgttttttg ttttgttttg ttttgttttt gagagggagt ctcactttgt     3840

gccctagact ggagtgcaat ggcgccatct cggcttactg caacctccac ctcccaggtg     3900

caagcgattc ccctgcctca gcttcccgag tagctgggat tacagatgtg agccaccgta     3960

cccagctaat ttttgtattt ttagtagaga cggggtttca ccatattggc caagctggtc     4020

tcgaactcct gacctcaggc gatccatctg tctcagcctc ccaaagtgct gggattacag     4080

gtgtgagcca ccgcgccagg cctcagccca cttcttttgg gtggcaatgg tttggatatc     4140

gtttgtcctc actaaaattc atgttgagat tcgagcccca gtgtggcagg tgttgggatg     4200

tggggcctca taaggagctg tgtggtcttg gaggtggagt cctcatggat agattaatgc     4260

ctgccttaag gggtgagtga gtgctcaccc ttgggaattt gggaatttgg ttttctctcc     4320

cttgcttcct tcagcaccat gtgatctctg tgcacacagc tgcatccttc tgccctcccc     4380

cagaagcagc agcagcctca gggatgaggg aggtcctcag tgagtgcacc tgcccagtct     4440

tgaaccttcc agccatcaga atctgagcca aatcaacctc ttcctttata aagacccagc     4500

ctcaggtctt ctgtcagagc aacacaaaat ggactcagca cggatcaaat tgtgtctccc     4560

ccacccccac aaaaaacttt atattaaaat cctaaccccc agcaaaaaaa aaaaaaaaaa     4620

aa                                                                    4622


<210>  2514
<211>  3610
<212>  DNA
<213>  homo sapiens

<400>  2514
gagaggctgt gggagaaggg agggaccaga ggagagagcg agagagggaa ccagacccca       60

gttcgccgac taagcagaag aaagatcaaa aaccggaaaa gaggagaaga gcaaacaggc      120

actttgagga acaatcccct ttaactccaa gccgacagcg gtctaggaat tcaagttcag      180

tgcctaccga agacaaaggc gccccgaggg agtggcggtg cgaccccagg gcgtgggccc      240

ggccgcggag cccacactgc ccggctgacc cggtggtctc ggaccatgtc tcccgcccca      300

agaccccccc gttgtctcct gctccccctg ctcacgctcg gcaccgcgct cgcctccctc      360

ggctcggccc aaagcagcag cttcagcccc gaagcctggc tacagcaata tggctacctg      420

cctcccgggg acctacgtac ccacacacag cgctcacccc agtcactctc agcggccatc      480

gctgccatgc agaagtttta cggcttgcaa gtaacaggca aagctgatgc agacaccatg      540

aaggccatga ggcgcccccg atgtggtgtt ccagacaagt ttggggctga gatcaaggcc      600

aatgttcgaa ggaagcgcta cgccatccag ggtctcaaat ggcaacataa tgaaatcact      660

ttctgcatcc agaattacac ccccaaggtg ggcgagtatg ccacatacga ggccattcgc      720

aaggcgttcc gcgtgtggga gagtgccaca ccactgcgct tccgcgaggt gccctatgcc      780

tacatccgtg agggccatga gaagcaggcc gacatcatga tcttctttgc cgagggcttc      840

catggcgaca gcacgccctt cgatggtgag ggcggcttcc tggcccatgc ctacttccca      900

ggccccaaca ttggaggaga cacccacttt gactctgccg agccttggac tgtcaggaat      960

gaggatctga atggaaatga catcttcctg gtggctgtgc acgagctggg ccatgccctg     1020

gggctcgagc attccagtga cccctcggcc atcatggcac ccttttacca gtggatggac     1080

acggagaatt ttgtgctgcc cgatgatgac cgccggggca tccagcaact ttatgggggt     1140

gagtcagggt tccccaccaa gatgccccct caacccagga ctacctcccg gccttctgtt     1200

cctgataaac ccaaaaaccc cacctatggg cccaacatct gtgacgggaa ctttgacacc     1260

gtggccatgc tccgagggga gatgtttgtc ttcaaggagc gctggttctg gcgggtgagg     1320

aataaccaag tgatggatgg atacccaatg cccattggcc agttctggcg gggcctgcct     1380

gcgtccatca acactgccta cgagaggaag gatggcaaat tcgtcttctt caaaggagac     1440

aagcattggg tgtttgatga ggcgtccctg gaacctggct accccaagca cattaaggag     1500

ctgggccgag ggctgcctac cgacaagatt gatgctgctc tcttctggat gcccaatgga     1560

aagacctact tcttccgtgg aaacaagtac taccgtttca acgaagagct cagggcagtg     1620

gatagcgagt accccaagaa catcaaagtc tgggaaggga tccctgagtc tcccagaggg     1680

tcattcatgg gcagcgatga agtcttcact tacttctaca aggggaacaa atactggaaa     1740

ttcaacaacc agaagctgaa ggtagaaccg ggctacccca agtcagccct gagggactgg     1800

atgggctgcc catcgggagg ccggccggat gaggggactg aggaggagac ggaggtgatc     1860

atcattgagg tggacgagga gggcggcggg gcggtgagcg cggctgccgt ggtgctgccc     1920

gtgctgctgc tgctcctggt gctggcggtg ggccttgcag tcttcttctt cagacgccat     1980

gggaccccca ggcgactgct ctactgccag cgttccctgc tggacaaggt ctgacgccca     2040

ccgccggccc gcccactcct accacaagga ctttgcctct gaaggccagt ggcagcaggt     2100

ggtggtgggt gggctgttcc catcgtcccg agccccctcc ccgcagcctc cttgcttctc     2160

tctgtcccct ggctggcctc cttcaccctg accgcctccc tccctcctgc cccggcattg     2220

catcttccct agataggtcc cctgagggct gagtgggagg gcggcccttt ccagcctctg     2280

cccctcaggg gaaccctgta gctttgtgtc tgtccagccc catctgaatg tgttgggggc     2340

tctgcacttg aaggcaggac cctcagacct cgctggtaaa ggtcaaatgg ggtcatctgc     2400

tccttttcca tcccctgaca taccttaacc tctgaactct gacctcagga ggctctgggc     2460

actccagccc tgaaagcccc aggtgtaccc aattggcagc ctctcactac tctttctggc     2520

taaaaggaat ctaatcttgt tgagggtaga gaccctgaga cagtgtgagg gggtggggac     2580

tgccaagcca ccctaagacc ttgggaggaa aactcagaga gggtcttcgt tgctcagtca     2640

gtcaagttcc tcggagatct gcctctgcct cacctacccc agggaacttc caaggaagga     2700

gcctgagcca ctggggacta agtgggcaga agaaaccctt ggcagccctg tgcctctcga     2760

atgttagcct tggatggggc tttcacagtt agaagagctg aaaccagggg tgcagctgtc     2820

aggtagggtg gggccggtgg gagaggcccg ggtcagagcc ctgggggtga gcctgaaggc     2880

cacagagaaa gaaccttgcc caaactcagg cagctggggc tgaggcccaa aggcagaaca     2940

gccagagggg gcaggagggg accaaaaagg aaaatgagga cgtgcagcag cattggaagg     3000

ctggggccgg gcaggccagg ccaagccaag cagggggcca cagggtgggc tgtggagctc     3060

tcaggaaggg ccctgaggaa ggcacacttg ctcctgttgg tccctgtcct tgctgcccag     3120

gcagcgtgga ggggaagggt agggcagcca gagaaaggag cagagaaggc acacaaacga     3180

ggaatgaggg gcttcacgag aggccacagg gcctggctgg ccacgctgtc ccggcctgct     3240

caccatctca gtgaggggca ggagctgggg ctcgcttagg ctgggtccac gcttccctgg     3300

tgccagcacc cctcaagcct gtctcaccag tggcctgccc tctcgctccc ccacccagcc     3360

cacccattga agtctccttg ggccaccaaa ggtggtggcc atggtaccgg ggacttggga     3420

gagtgagacc cagtggaggg agcaagagga gagggatgtc gggggggtgg ggcacggggt     3480

aggggaaatg gggtgaacgg tgctggcagt tcggctagat ttctgtcttg tttgtttttt     3540

tgttttgttt aatgtatatt tttattataa ttattatata tgaattccat tcaaaaaaaa     3600

aaaaaaaaaa                                                            3610


<210>  2515
<211>  5530
<212>  DNA
<213>  homo sapiens

<400>  2515
ttgttgggcg acttttgcaa caactcgccg cgccgcggcc tccgcgcgcc gccgccgcca       60

ccgcagccgc cggctccccg ccgcccgggc ccgggccggc cgcgccgggg gccgccgcgc      120

ccgccgcccg ctgcctgcgc cgccggccgg gcatgagtta gtcgcagaca tggacaccaa      180

acatttcctg ccgctcgatt tctccaccca ggtgaactcc tccctcacct ccccgacggg      240

gcgaggctcc atggctgccc cctcgctgca cccgtccctg gggcctggca tcggctcccc      300

gggacagctg cattctccca tcagcaccct gagctccccc atcaacggca tgggcccgcc      360

tttctcggtc atcagctccc ccatgggccc ccactccatg tcggtgccca ccacacccac      420

cctgggcttc agcactggca gcccccagct cagctcacct atgaaccccg tcagcagcag      480

cgaggacatc aagccccccc tgggcctcaa tggcgtcctc aaggtccccg cccacccctc      540

aggaaacatg gcttccttca ccaagcacat ctgcgccatc tgcggggacc gctcctcagg      600

caagcactat ggagtgtaca gctgcgaggg gtgcaagggc ttcttcaagc ggacggtgcg      660

caaggacctg acctacacct gccgcgacaa caaggactgc ctgattgaca agcggcagcg      720

gaaccggtgc cagtactgcc gctaccagaa gtgcctggcc atgggcatga agcgggaagc      780

cgtgcaggag gagcggcagc gtggcaagga ccggaacgag aatgaggtgg agtcgaccag      840

cagcgccaac gaggacatgc cggtggagag gatcctggag gctgagctgg ccgtggagcc      900

caagaccgag acctacgtgg aggcaaacat ggggctgaac cccagctcgc cgaacgaccc      960

tgtcaccaac atttgccaag cagccgacaa acagcttttc accctggtgg agtgggccaa     1020

gcggatccca cacttctcag agctgcccct ggacgaccag gtcatcctgc tgcgggcagg     1080

ctggaatgag ctgctcatcg cctccttctc ccaccgctcc atcgccgtga aggacgggat     1140

cctcctggcc accgggctgc acgtccaccg gaacagcgcc cacagcgcag gggtgggcgc     1200

catctttgac agggtgctga cggagcttgt gtccaagatg cgggacatgc agatggacaa     1260

gacggagctg ggctgcctgc gcgccatcgt cctctttaac cctgactcca aggggctctc     1320

gaacccggcc gaggtggagg cgctgaggga gaaggtctat gcgtccttgg aggcctactg     1380

caagcacaag tacccagagc agccgggaag gttcgctaag ctcttgctcc gcctgccggc     1440

tctgcgctcc atcgggctca aatgcctgga acatctcttc ttcttcaagc tcatcgggga     1500

cacacccatt gacaccttcc ttatggagat gctggaggcg ccgcaccaaa tgacttaggc     1560

ctgcgggccc atcctttgtg cccacccgtt ctggccaccc tgcctggacg ccagctgttc     1620

ttctcagcct gagccctgtc cctgcccttc tctgcctggc ctgtttggac tttggggcac     1680

agcctgtcac tgctctgcct aagagatgtg ttgtcaccct ccttatttct gttactactt     1740

gtctgtggcc cagggcagtg gctttcctga ggcagcagcc ttcgtggcaa gaactagcgt     1800

gagcccagcc aggcgcctcc ccaccgggct ctcaggacac cctgccacac cccacggggc     1860

ttgggcgact acagggtctt cgggccccag ccctggagct gcaggagttg ggaacggggc     1920

ttttgtttcc gttgctgttt atcgatgctg gttttcagaa ttcctgtgtg gccctcctgt     1980

ctggagtgac atcttcatct gctctgaata ctggtgccca gccagcccgt gacagcttcc     2040

ccctaatcag gaggggacag ctgggggcgc aagctggtgt gtcatcagca aagacctcag     2100

ccgcctcggg gatgagaggg gactcgtggg gcaagcaagc tgccctgtgc tctgagtgag     2160

ggggaaggta gccccttttt ccaaagataa ctcacagttt tgccctcgag ccaatgagaa     2220

catgagctgc cctctgtgca aggtttcggg gccacctcca ggctgcaggg gcgggtcact     2280

cacccccctg ttttctctct gccttggtgt tctggtttca gactcccgac tccccgttca     2340

gaccagagtg ccccggcccc tccccagcct gagtcttctc cttgctctgc ggggtgggct     2400

gaggcttgtc cttgtttcct gcagggctgg ccctggctcg ggcagggtgg ggcatcacca     2460

cctcactggc cttgctggag gcacagggct ctgcggacct gcagccatct gtgaggcccg     2520

cggggatggg aggggaggag ggtggcctgt tggtttccct cagagggggc aggtggcctg     2580

gagagagagg ggctcaggaa ctgggagcct cgtgggtggg gcagatgctc cgcggcctgg     2640

agtggctctg ccggggcatt ggtgggaccc ctgctcaggc cttctctctg gctgccagtt     2700

gtgtctaaaa gactcttgga atctgagaac ccggagtcgc agcgccctcg ggcctgggcc     2760

acacgcaggc cctggtggga ccacccagcc tggtattgtc cacggacagc gttgttcacc     2820

cagagcctta cttgggagcc tcactgaacg cctgctctgg ttgaaggtgg ggtgggggcg     2880

gggcttgggg cctccctggc tcagcccagt gcggcctggc gctcctcccg caggctctgc     2940

ccccgggctc cggtggtgcg gggccctctc aggttgaact cgcctctttt gcactggaag     3000

gccctccctt tggcctgagt acttttcccg ttcacgcctc agtcccgtgg acccagcctt     3060

tgtcagtggc aggtgcctga acagagggtg gatggggggg ataccggagg gggtcttgtc     3120

ttcccagccg cagtctagga atgatgcggg ggggtggacg ccttctccat agtctttccc     3180

cacctggagc aggggcttcc tcagtggtga ggggagctgc ctacaggttg gaccgggagg     3240

cagtggcttg gagaggcagc tttccagcct tggtggggaa gaaagtgtcc attctttgcc     3300

ttcctggagc tcccagccag agctgagctt aggcacccga gtggagcctg cagctgagtc     3360

tgtgcccgag acaggctgtc agagattcca gaagcctctc ctccccgccg ccctccaccc     3420

ctgcctttca gcgttgtgga tccctagagg tggccccctg cccgatccac cgtcctgagg     3480

cagagtgttg agcctcatac ctgtaccagg tccccggcca gctgggcccc tcccaggcac     3540

tgccaggaag ccccagctgc ccctggcggg tgtggtggaa atggcaggag ggtgcaggta     3600

ctcttggggc cccagcggtg ggagtgcaaa agacccaacg ccaacacctg gtgccttctg     3660

cagccagcgc ccacccatcc gtgcccggac ccttgggaat gcccgcggct ccagaggaaa     3720

aagcccaggg acggggcctc cgttgcgggg ggtcggctgc ttcttgggaa ctttgtcgtt     3780

tccggcgctg gctggctggc tggctggctg taaagcactg aagccccccg gccgccaacc     3840

cctgaaagca gaacctggcc tccctggcca cagcagcctt acccaccgct ctacgtgtcc     3900

cgggcacttc ccgcagcctt cccgtccctt tctcatcggc cttgtagttg tacagtgctg     3960

ttggtttgaa aaggtgatgt gtggggagtg cggctcatca ctgagtagag aggtagaatt     4020

tctatttaac cagacctgta gtagtattac caatccagtt caattaaggt gattttttgt     4080

aattattatt attttggtgg gacaatcttt aattttctaa agatagcact aacatcagct     4140

cattagccac ctgtgcctgt ccccgccttg gcccggctgg atgaagcggc ttccccgcag     4200

ggcccccact tcccagtggc tgcttcctgg ggacccaggg caccccggca ccttcaggca     4260

cgctcctcag ctggtcacct cccggctttg ccgttcagat ggggctcctg aggctcagga     4320

gtgaagatgc cacagagccg ggctccccta ggctgcgtcg ggcatgcttg gaagctggcc     4380

tgccaggacc ttccaccctg gggcctgtgt cagccgccgg ccctccgcac cctggaagca     4440

cacggcctct gggaaggaca gccctgacct tcggttttcc gagcacggtg tttcccaaga     4500

attctgggct ggcggcctgg tggcagtgct ggagatgacc ccgagcccct ccccgtgggg     4560

cacccaggag ggccctgccg gaatgtgcag cctgtgggta gtcggctggt gtccctgtcg     4620

tggagctggg gtgcgtgatc tggtgctcgt ccacgcaggt gtgtggtgta aacatgtatg     4680

tgctgtacag agagacgcgt gtggagagag ccgcacacca gcgccaccca ggaaaggcgg     4740

agcggttacc agtgttttgt gtttattttt aatcaagacg tttcccctgt tttcctataa     4800

atttgcttcg tgtaagcaag tacataagga ccctcctttg gtgaaatccg ggttcgaatg     4860

aatatctcaa ggcaggagat gcatctattt taagatgctt tggagcagac agctttagcc     4920

gttcccaatc cttagcaatg ccttagctgg gacgcatagc taatacttta gagaggatga     4980

cagatccata aagagagtaa agataagaga aaatgtctaa agcatctgga aaggtaaaaa     5040

aaaaaaatct atttttgtac aaatgtaatt ttatccctca tgtatacttg gatatggcgg     5100

ggggagggct gggactgttt cgtttctgct tctagagatt gaggtgaaag cttcgtccga     5160

gaaacgccag gacagacgat ggcagaggag agggctcctg tgacggcggc gaggcttggg     5220

aggaaaccgc cgcaatgggg gtgtcttccc tcggggcagg agggtgggcc tgaggctttc     5280

aagggttttc ttccctttcg agtaattttt aaagccttgc tctgttgtgt cctgttgccg     5340

gctctggcct tcctgtgact gactgtgaag tggcttctcc gtacgattgt ctctgaaaca     5400

tcgtggcctc aggtgccagg gtttgatgga cagtagcatt agaattgtgg aaaaggaaca     5460

cgcaaaggga gaagtgtgag aggagaaaca aaatatgagc gtttaaaata catcgccatt     5520

cagttcgttt                                                            5530


<210>  2516
<211>  2881
<212>  DNA
<213>  homo sapiens

<400>  2516
acccggaggc cgaccttccg ccgaggcggt gcaggaagga acgggagagg gagaagtttg       60

gtagggaagg aattggggat taagcggtcc ctcagaggat ccagcgaggg gcgccaacaa      120

gaggcgaaga ggtggcacca gggcggcggc aggaagagga gcgggagcag gagcgcggag      180

cggagcgtcc cgacccgccg tgcgtacttt ctggagggaa ggggcggggg aatcggcccc      240

tgagggaagc gcccggtggc gagggggtta gccaagttcc ggctgcggcg ccactccctc      300

ggttccacga gaggaaagtt ttttttttcc agacgcttcc gccggctcgc gccctccggg      360

cccagcctcc cgagccttcg gagcgggcgc cgtcccagcc cagctccggg gaaacgcgag      420

ccgcgatgcc tggggggtgc tcccggggcc ccgccgccgg ggacgggcgt ctgcggctgg      480

cgcgactagc gctggtactc ctgggctggg tctcctcgtc ttctcccacc tcctcggcat      540

cctccttctc ctcctcggcg ccgttcctgg cttccgccgt gtccgcccag cccccgctgc      600

cggaccagtg ccccgcgctg tgcgagtgct ccgaggcagc gcgcacagtc aagtgcgtta      660

accgcaatct gaccgaggtg cccacggacc tgcccgccta cgtgcgcaac ctcttcctta      720

ccggcaacca gctggccgtg ctccctgccg gcgccttcgc ccgccggccg ccgctggcgg      780

agctggccgc gctcaacctc agcggcagcc gcctggacga ggtgcgcgcg ggcgccttcg      840

agcatctgcc cagcctgcgc cagctcgacc tcagccacaa cccactggcc gacctcagtc      900

ccttcgcttt ctcgggcagc aatgccagcg tctcggcccc cagtcccctt gtggaactga      960

tcctgaacca catcgtgccc cctgaagatg agcggcagaa ccggagcttc gagggcatgg     1020

tggtggcggc cctgctggcg ggccgtgcac tgcaggggct ccgccgcttg gagctggcca     1080

gcaaccactt cctttacctg ccgcgggatg tgctggccca actgcccagc ctcaggcacc     1140

tggacttaag taataattcg ctggtgagcc tgacctacgt gtccttccgc aacctgacac     1200

atctagaaag cctccacctg gaggacaatg ccctcaaggt ccttcacaat ggcaccctgg     1260

ctgagttgca aggtctaccc cacattaggg ttttcctgga caacaatccc tgggtctgcg     1320

actgccacat ggcagacatg gtgacctggc tcaaggaaac agaggtagtg cagggcaaag     1380

accggctcac ctgtgcatat ccggaaaaaa tgaggaatcg ggtcctcttg gaactcaaca     1440

gtgctgacct ggactgtgac ccgattcttc ccccatccct gcaaacctct tatgtcttcc     1500

tgggtattgt tttagccctg ataggcgcta ttttcctcct ggttttgtat ttgaaccgca     1560

aggggataaa aaagtggatg cataacatca gagatgcctg cagggatcac atggaagggt     1620

atcattacag atatgaaatc aatgcggacc ccagattaac gaacctcagt tctaactcgg     1680

atgtctgaga aatattagag gacagaccaa ggacaactct gcatgagatg tagacttaag     1740

ctttatccct actaggcttg ctccactttc atcctccact atagatacaa cggactttga     1800

ctaaaagcag tgaaggggat ttgcttcctt gttatgtaaa gtttctcggt gtgttctgtt     1860

aatgtaagac gatgaacagt tgtgtatagt gttttaccct cttctttttc ttggaactcc     1920

tcaacacgta tggagggatt tttcaggttt cagcatgaac atgggcttct tgctgtctgt     1980

ctctctctca gtacagttca aggtgtagca agtgtaccca cacagatagc attcaacaaa     2040

agctgcctca actttttcga gaaaaatact ttattcataa atatcagttt tattctcatg     2100

tacctaagtt gtggagaaaa taattgcatc ctataaactg cctgcagacg ttagcaggct     2160

cttcaaaata actccatggt gcacaggagc acctgcatcc aagagcatgc ttacatttta     2220

ctgttctgca tattacaaaa aataacttgc aacttcataa cttctttgac aaagtaaatt     2280

acttttttga ttgcagttta tatgaaaatg tactgatttt tttttaataa actgcatcga     2340

gatccaaccg actgaattgt taaaaaaaaa aaaaataaag attcttaaaa gaattacagt     2400

gtgtgcaagt ttgctttgaa aaaaggatga agggcaggag tattcaatgg tcttggttcc     2460

gatgataatt attacttaac atagctgaga atcaaactgt agcaatgtct aatataaata     2520

gacttgggag atcgttttga aatggtggat ccttttagta tttaaatgga gagtttgagt     2580

attcatgtga ctgtatggtc ccaaagttaa tgctatttat gaaacagttt tgtaagaaca     2640

taatgaagtt ggtaaaagct aagcgttctg cacaataaac agttcccagt ttggggcttt     2700

ttcaaggcta atgaagttat tgttggtcta gaaaaatagt atttacttaa taaaactctg     2760

tttgaaattg ttctgtggat ttttagagca gaatttgaaa caaatgtaat gcaaataaat     2820

ataaagataa agtgtcttaa agacaatatt ctgaaataaa agatataaaa tataatttaa     2880

a                                                                     2881


<210>  2517
<211>  3312
<212>  DNA
<213>  homo sapiens

<400>  2517
tttggcatcc aggagaccgt gcgggagacc gacgctgagc gccggcctcg ccctcggcgg       60

cccctccctc ctccttaccc cgcctccccc ggcccgcccc tccctccccg gaggagcagt      120

ctctccgcgc gtctcccgga gctttctcca ttgtctctgc ctttacaaca gagggagacg      180

atggactgag ctgatccgca ccatggagtc tcgggtctta ctgagaacat tctgtttgat      240

cttcggtctc ggagcagttt gggggcttgg tgtggaccct tccctacaga ttgacgtctt      300

aacagagtta gaacttgggg agtccacgac cggagtgcgt caggtcccgg ggctgcataa      360

tgggacgaaa gcctttctct ttcaagatac tcccagaagc ataaaagcat ccactgctac      420

agctgaacag ttttttcaga agctgagaaa taaacatgaa tttactattt tggtgaccct      480

aaaacagacc cacttaaatt caggagttat tctctcaatt caccacttgg atcacaggta      540

cctggaactg gaaagtagtg gccatcggaa tgaagtcaga ctgcattacc gctcaggcag      600

tcaccgccct cacacagaag tgtttcctta cattttggct gatgacaagt ggcacaagct      660

ctccttagcc atcagtgctt cccatttgat tttacacatt gactgcaata aaatttatga      720

aagggtagta gaaaagccct ccacagactt gcctctaggc acaacatttt ggctaggaca      780

gagaaataat gcgcatggat attttaaggg tataatgcaa gatgtccaat tacttgtcat      840

gccccaggga tttattgctc agtgcccaga tcttaatcgc acctgtccaa cttgcaatga      900

cttccatgga cttgtgcaga aaatcatgga gctacaggat attttagcca aaacatcagc      960

caagctgtct cgagctgaac agcgaatgaa tagattggat cagtgctatt gtgaaaggac     1020

ttgcaccatg aagggaacca cctaccgaga atttgagtcc tggatagacg gctgtaagaa     1080

ctgcacatgc ctgaatggaa ccatccagtg tgaaactcta atctgcccaa atcctgactg     1140

cccacttaag tcggctcttg cgtatgtgga tggcaaatgc tgtaaggaat gcaaatcgat     1200

atgccaattt caaggacgaa cctactttga aggagaaaga aatacagtct attcctcttc     1260

tggagtatgt gttctctatg agtgcaagga ccagaccatg aaacttgttg agagttcagg     1320

ctgtccagct ttggattgtc cagagtctca tcagataacc ttgtctcaca gctgttgcaa     1380

agtttgtaaa ggttatgact tttgttctga aaggcataac tgcatggaga attccatctg     1440

cagaaatctg aatgacaggg ctgtttgtag ctgtcgagat ggttttaggg ctcttcgaga     1500

ggataatgcc tactgtgaag acatcgatga gtgtgctgaa gggcgccatt actgtcgtga     1560

aaatacaatg tgtgtcaaca ccccgggttc ttttatgtgc atctgcaaaa ctggatacat     1620

cagaattgat gattattcat gtacagaaca tgatgagtgt atcacaaatc agcacaactg     1680

tgatgaaaat gctttatgct tcaacactgt tggaggacac aactgtgttt gcaagccggg     1740

ctatacaggg aatggaacga catgcaaagc attttgcaaa gatggctgta ggaatggagg     1800

agcctgtatt gccgctaatg tgtgtgcctg cccacaaggc ttcactggac ccagctgtga     1860

aacggacatt gatgaatgct ctgatggttt tgttcaatgt gacagtcgtg ctaattgcat     1920

taacctgcct ggatggtacc actgtgagtg cagagatggc taccatgaca atgggatgtt     1980

ttcaccaagt ggagaatcgt gtgaagatat tgatgagtgt gggaccggga ggcacagctg     2040

tgccaatgat accatttgct tcaatttgga tggcggatat gattgtcgat gtcctcatgg     2100

aaagaattgc acaggggact gcatccatga tggaaaagtt aagcacaatg gtcagatttg     2160

ggtgttggaa aatgacaggt gctctgtgtg ctcatgtcag aatggattcg ttatgtgtcg     2220

acggatggtc tgtgactgtg agaatcccac agttgatctt ttttgctgcc ctgaatgtga     2280

cccaaggctt agtagtcagt gcctccatca aaatggggaa actttgtata acagtggtga     2340

cacctgggtc cagaattgtc aacagtgccg ctgcttgcaa ggggaagttg attgttggcc     2400

cctgccttgc ccagatgtgg agtgtgaatt cagcattctc ccagagaatg agtgctgccc     2460

gcgctgtgtc acagaccctt gccaggctga caccatccgc aatgacatca ccaagacttg     2520

cctggacgaa atgaatgtgg ttcgcttcac cgggtcctct tggatcaaac atggcactga     2580

gtgtactctc tgccagtgca agaatggcca catctgttgc tcagtggatc cacagtgcct     2640

tcaggaactg tgaagttaac tgtctcatgg gagatttctg ttaaaagaat gttctttcat     2700

taaaagacca aaaagaagtt aaaacttaaa ttgggtgatt tgtgggcagc taaatgcagc     2760

tttgttaata gctgagtgaa ctttcaatta tgaaatttgt ggagcttgac aaaatcacaa     2820

aaggaaaatt actggggcaa aattagacct caagtctgcc tctactgtgt ctcacatcac     2880

catgtagaag aatgggcgta cagtatatac cgtgacatcc tgaaccctgg atagaaagcc     2940

tgagcccatt ggatctgtga aagcctctag cttcactggt gcagaaaatt ttcctctaga     3000

tcagaatctt caagaatcag ttaggttcct cactgcaaga aataaaatgt caggcagtga     3060

atgaattata ttttcagaag taaagcaaag aagctataac atgttatgta cagtacactc     3120

tgaaaagaaa tctgaaacaa gttattgtaa tgataaaaat aatgcacagg catggttact     3180

taatattttc taacaggaaa agtcatccct atttccttgt tttactgcac ttaatattat     3240

ttggttgaat ttgttcagta taagctcgtt cttgtgcaaa attaaataaa tatttctctt     3300

accttataac ac                                                         3312


<210>  2518
<211>  3995
<212>  DNA
<213>  homo sapiens

<400>  2518
attttcaaat ccccggatga cggcggtggc ggctgcagtc cgctgacagg cgctttctgc       60

ctggcagagg ctggcgggca tcgtgcccgt ccctgccggt ctcccgggca cccggccacc      120

gccccacccc ctcctccgtg ccatggagcc cgagctggcg gctcagaagc agcctcgacc      180

gcggaggcga agccgccggg cctctgggct cagcacggag ggagcgacgg ggccttcggc      240

cgacacctcc gggtcggagc tggacgggag atgttccctt cggagaggca gctccttcac      300

attcttaaca cctggcccca actgggactt cactttgaaa agaaaacgca gagagaaaga      360

tgatgatgtt gtaagcctta gcagccttga tctgaaggag ccaagcaata aaagagttcg      420

acctctggct cgtgtcacgt ccttggcaaa tttaatctct cctgtaagaa atggagctgt      480

cagacgtttt ggtcaaacaa tacagtcatt tacccttcgt ggtgaccaca gatccccagc      540

ctctgcccag aagttttcta gcaggtcaac agtcccaaca cccgccaaga gaaggagcag      600

tgcactgtgg tcagagatgc tggacatcac catgaaggag tctctcacca ccagggagat      660

cagacggcag gaggcaatat atgaaatgtc ccgaggtgaa caggatttaa ttgaggatct      720

caaacttgca agaaaggcct accatgaccc catgttaaag ttgtccatca tgtcagaaga      780

ggaactcaca catatatttg gtgatctgga ctcttacata cctctgcatg aagatttgtt      840

gacaagaata ggagaagcaa ccaagcctga tggaacagtg gagcagattg gtcacattct      900

cgtgagctgg ttaccgcgct tgaatgccta cagaggttac tgtagtaacc agctggcagc      960

caaagctctt cttgatcaaa agaaacagga tccaagagtc caagacttcc tccagcgatg     1020

tctcgagtct cccttcagtc gaaaactaga tctttggagt ttcctagata tccctcgaag     1080

tcgcctagtc aaataccctt tactgttaaa agaaattctt aaacacactc caaaagagca     1140

ccctgatgtt cagcttctgg aggatgctat attgataata cagggagtcc tctctgatat     1200

caacttgaag aaaggtgaat ccgagtgcca gtattacatc gacaagctgg agtacctgga     1260

tgaaaagcag agggacccca gaatcgaagc gagcaaagtg ctgctgtgcc atggggagct     1320

gcggagcaag agtggacata aactttacat tttcctgttt caagacatct tggttctgac     1380

tcggcccgtc acacggaacg aacggcactc ttaccaggtt taccggcagc caatcccagt     1440

ccaagagcta gtcctagaag acctgcagga tggagatgtg agaatgggag gctcctttcg     1500

aggagctttc agtaactcag agaaagctaa aaatatcttt agaattcgct tccatgaccc     1560

ctctccagcc cagtctcaca ctctgcaagc caatgacgtg ttccacaagc agcagtggtt     1620

caactgtatt cgagcggcca ttgccccctt ccagtcggca ggcagtccac ctgagctgca     1680

gggcctgccg gagctgcacg aagagtgtga ggggaaccac ccctctgcga ggaaactcac     1740

agcccagagg agggcatcca cagtttccag tgttactcag gtagaagttg atgaaaacgc     1800

ttacagatgt ggctctggca tgcagatggc agaggacagc aagagcttaa agacacacca     1860

gacacagccc ggcatccgaa gagcgaggga caaagccctt tctggtggca aacggaaaga     1920

gactttggtg tagagaaggc tctgtgtgtt aactgatggg agagactgtt tgtttataaa     1980

tgtgtacagt tttgttttct cgtaagggga gcatcatagg gttactttat accagttgta     2040

acattttcat tgtttttggt tgttcttttt tcttttttta atggcagcta aagatataca     2100

gattactgtt aaattgcagt cctttttttt ttaaagatat tttcttgaat tatttagaac     2160

atggtaagcc tggtattttt taatcaaaca aaatatttat gaaatgggtt ttctcttaat     2220

tctggattca tcatggcttt ctaataccaa ttgtaatatt tacaatattc accaaaactt     2280

agaattttgc aaatgctgga attctgccag tgtttctttg ctaagccttg catgcaaaat     2340

ttgaaatttt aacattggca cccaaaacct acatggaatg tatgtctgga gtatttcaaa     2400

ctttacattg aaacataatt tccttggaaa acaaaccata agcctgagga ggtttttatc     2460

aactggaatg ctttatatta gtttgttttt cactgtacat tcctcatttt acattcattt     2520

aacctgccga ttatttaatt tttttattgt aaagtagttt ttagcatttg cttttatttt     2580

tttactttga tgccttttca aattggcatg tctttaaagt atttttcttc ctgattaaaa     2640

atgtgtgtgt atgtgtgtgt gtgtgtgtat atatatatat atttttaaat cacattaatt     2700

ttaccaagtg aaaccaagcc atactgtttt tgagccaatt aagaaaattg ccatttttaa     2760

agtgtagcat ttcagggtaa agacccatga aatggcttga tgtattctag actactgaaa     2820

gaaaaccact tcaaagattt tgttgaaagt tttagtgttg tctgaaatgc aagagggaag     2880

gtgattggta gtgagttaaa agaaaaagag aggaaaagag agtagttttg tcttcaagta     2940

aaatgtctgg ttgtgccaga catttcacaa gtgtgaaagg agataggaga agctcaactt     3000

gagggcgtgt agtaagttgt agaaggctcg aggggacgtg gacttatttg ccttggtttg     3060

caatacctgc aaataatgag tttgaaaaga aacaatgaaa tgtgttaaaa atttgaccat     3120

attagataaa ttttggtgga tttagtcata agatggaaaa agactggtga atcttttatt     3180

acaaaatgtt tctgttaaaa tgggatcatc atctttgaaa ggggggagga ggagtaaaag     3240

cccgattata atggtgatca attcaagtca gtgttgacta ttctgtgaaa tatatttggc     3300

cagtggaaat gataatcaga aaagactgta aatagatcca tccaaatgat ttctctgtac     3360

aaatgaatga tactattaaa aaaaaaaaaa gcacacacat aatcaccctg aaggtttctt     3420

gcctggtggc tatgttgggg gcatttggca aaatatgctg gtgtggcaaa ggaggtagtg     3480

gtaagcctca taaaagttag taaaaattgt agttcaacct ttgaaatcat tgatgaatca     3540

gcgaaaggta ggtaagtctt gtgttaggaa atcttttaag aacatggtgt aatcagacac     3600

agcaattgta ttgaaaataa ctgaacacct gttactttct ggataggata gtaagggtag     3660

tagtggcaaa ggatcctgat taatttcaga ttttaatgta agtacctcag gttcttgtct     3720

ttggaaattc acattcataa gtgtatatta caccaatgat tgtgatctgc aacaccagaa     3780

agcaagattt ctaatcattt ccagaggtgt tgtatagaat agttattcca gagttacctt     3840

gatcagcttc tgaagtttaa gaagcaagta atagttcaag tgttgttaat ggaattatgt     3900

tttatttaaa accgtatctt cttttggttc cctcaaaggt aaaaataaga cccagaatct     3960

gagtaaatct attaaatgaa tgttcttcag aaata                                3995


<210>  2519
<211>  864
<212>  DNA
<213>  homo sapiens

<400>  2519
gagccattga ttggtcgacg cccccagagg gttacaattc aaacgcgggc gggcgggccc       60

gcagtcctgc agttgcagtc gtgttctccg agttcctgtc tctctgccaa cgccgcccgg      120

atggcttccc aaaaccgcga cccagccgcc actagcgtcg ccgccgcccg taaaggagct      180

gagccgagcg ggggcgccgc ccggggtccg gtgggcaaaa ggctacagca ggagctgatg      240

accctcatga tgtctggcga taaagggatt tctgccttcc ctgaatcaga caaccttttc      300

aaatgggtag ggaccatcca tggagcagct ggaacagtat atgaagacct gaggtataag      360

ctctcgctag agttccccag tggctaccct tacaatgcgc ccacagtgaa gttcctcacg      420

ccctgctatc accccaacgt ggacacccag ggtaacatat gcctggacat cctgaaggaa      480

aagtggtctg ccctgtatga tgtcaggacc attctgctct ccatccagag ccttctagga      540

gaacccaaca ttgatagtcc cttgaacaca catgctgccg agctctggaa aaaccccaca      600

gcttttaaga agtacctgca agaaacctac tcaaagcagg tcaccagcca ggagccctga      660

cccaggctgc ccagcctgtc cttgtgtcgt ctttttaatt tttccttaga tggtctgtcc      720

tttttgtgat ttctgtatag gactctttat cttgagctgt ggtatttttg ttttgttttt      780

gtcttttaaa ttaagcctcg gttgagccct tgtatattaa ataaatgcat ttttgtcctt      840

ttttagacaa aaaaaaaaaa aaaa                                             864


<210>  2520
<211>  810
<212>  DNA
<213>  homo sapiens

<400>  2520
gagccattga ttggtcgacg cccccagagg gttacaattc aaacgcgggc gggcgggccc       60

gcagtcctgc agttgcagtc gtgttctccg agttcctgtc tctctgccaa cgccgcccgg      120

atggcttccc aaaaccgcga cccagccgcc actagcgtcg ccgccgcccg taaaggagct      180

gagccgagcg ggggcgccgc ccggggtccg gtgggcaaaa ggctacagca ggagctgatg      240

accctcatga tgtctggcga taaagggatt tctgccttcc ctgaatcaga caaccttttc      300

aaatgggtag ggaccatcca tggagcagct ggaacagcag tggggagcat cagaaccagc      360

tcaacagttt gtctactgtc cggtcccaga gaaactcaag attctagcaa gccccttgtg      420

tggggcttgg gttgggacat gaggctgctg ctggagctta ctctgcaact gtttctccaa      480

atgccagaac ccaacattga tagtcccttg aacacacatg ctgccgagct ctggaaaaac      540

cccacagctt ttaagaagta cctgcaagaa acctactcaa agcaggtcac cagccaggag      600

ccctgaccca ggctgcccag cctgtccttg tgtcgtcttt ttaatttttc cttagatggt      660

ctgtcctttt tgtgatttct gtataggact ctttatcttg agctgtggta tttttgtttt      720

gtttttgtct tttaaattaa gcctcggttg agcccttgta tattaaataa atgcattttt      780

gtcctttttt agacaaaaaa aaaaaaaaaa                                       810


<210>  2521
<211>  3673
<212>  DNA
<213>  homo sapiens

<400>  2521
gacggtgctg tccaggggga ggcgggcgga gggaaggcgc tgccgctgct gccgccgcct       60

cgcccgaagc gacacagacg ctgggagcgg ccgaggcgag tgatttcttc tgacttgagc      120

ctgcagtgtg ctgtgagaga tctaccacta gattatctca actttggtct cctgggacca      180

ctcgttgctg acagtcagaa attgcagggc atctgatctc ctggtgttaa aatctgtcgt      240

gataccgagg aaggccccga gatcccaggc actgagtgac tgcatactct gaattcttgc      300

cgccaggatg gggaaacaga acagcaagct gcgcccggag gtcatgcagg acttgctgga      360

aagcacagac tttacagagc atgagatcca ggaatggtat aaaggcttct tgagagactg      420

ccccagtgga catttgtcaa tggaagagtt taagaaaata tatgggaact ttttccctta      480

tggggatgct tccaaatttg cagagcatgt cttccgcacc ttcgatgcaa atggagatgg      540

gacaatagac tttagagaat tcatcatcgc cttgagtgta acttcgaggg ggaagctgga      600

gcagaagctg aaatgggcct tcagcatgta cgacctggac ggaaatggct atatcagcaa      660

ggcagagatg ctagagatcg tgcaggcaat ctataagatg gtttcctctg taatgaaaat      720

gcctgaagat gagtcaaccc cagagaaaag aacagaaaag atcttccgcc agatggacac      780

caatagagac ggaaaactct ccctggaaga gttcatccga ggagccaaaa gcgacccgtc      840

cattgtgcgc ctcctgcagt gcgacccgag cagtgccggc cagttctgag ccctgcgccc      900

accaatcgaa ttgtagagct gcttgtgttc ccttttgatt cttcttttta acaatttttt      960

tttttttttg ccaaacaata tcaatggtga tgccgtcccc tgtgcggtct gatgcgcctt     1020

cctccgtgac gccttcagct tcttttgtcg tggatgcttc gtgggaatgc ccagagcccc     1080

agtgtgcttg tggagagcat ggacagactt cgtggtgttc attgtttgat gatttttaat     1140

cgttactatt attttttttt attctaatgt ctctgttcta aaacgtaaga ctcgggggtt     1200

ggggcaaaag aagggaaacc catccagtcc tgtgattcta ttgcaagctt caaggggctt     1260

ttgtttgaaa gacaaaactc cccacctgaa tctgttgtca cacgtgccgt aggggtgatg     1320

gatggcaccg gatgctggat tccccaagaa caagttaccc tctggggtga ggctattcca     1380

gcgagctggg acatttcccc atgggggccc actcccctct cttccccagc aggctgtagt     1440

ttctaagctg tgaacatttc aagataaatt aacagaggag aggaaaaaga tggctcagct     1500

attttttcac aggtttacac tagttgagct aatatgcgtg tctttggaaa ttaaacacaa     1560

atggtaacat attccaaaac cagacccatc ttgttgccta ttgtgataaa ataaaaagac     1620

ggctgtatat aacatattgg gtaatgcaga ccaaattaag tgttttgcct tgtttaaatg     1680

aaatgcatgt ttagtgagca ctaatacaat cttattccag aagactgttt ttagtagctt     1740

attgtgaagt aagacaacta taatgaatgt ctgtcttgtt tggaagtcat atctgtcttt     1800

gcacaaatgt accaatcgac aagtatattt tatatattcc ataaaaatac aaagtaaccc     1860

tgactagggc ccaactttaa ttttgaatgc atttccagag tggccatgcc tagagggcag     1920

atgcagagca ggtggtagtg ggacaggaca attggagcac aggaatgtta acatgtatga     1980

caggggacca gtagggtggt ttccctctca ggcccagcag cccattgaca gcattagact     2040

ggcggcatgg tgcttttctg agcagatcaa tactctgcag actcgaaaaa acatcacata     2100

cattcttgga acttcccagt ggtttaatct atgtgcatgg ttagggagcc aggtctggaa     2160

tattcagttt ccctgcccct gttaaagaat cagaggttgg gcagtcatca aattcatcat     2220

aaagacatgg gcaagtgtgt ctgtggtttc caaggccccc ctatggagaa tccaaaagta     2280

ttttccattg ccgtgctctt tgaatgcaga cttctatttc cagaagtgac agcacaagtc     2340

tgagttgctg tttggtctgg tgacctcaga cacactaatt tgaattgaaa gctaagagta     2400

aaaatttgct ggttacaggc gagtcatact cttgcaagta gttagcaaag ggaggcccaa     2460

attctcaagg ttgttgatgg ggaacttgcc actaagagaa ggcagagagg tccctagtgg     2520

gtatatttgc tgccaagcca cttgccaaag aagaggaacc acagaaagag agacatcatg     2580

accaggagaa aaatgtgact agacatgcta acctccaggt ttttatatat gacttgagtc     2640

tgctgtaatt ggcagcagaa atccaaattt gtatggtaga ccaaaaagaa ccaaatccat     2700

agggtgaaat tttgagacct agactctgta aaaataatcc tagtcttcct ccaggggtca     2760

gttcctcaca gtggttctgt accaaaactt gccaaattcc tccatggcca agtgttaaaa     2820

tctgtgtttg gaaaatagcg aattaaccta agacacagaa ggcagactgg gtgaggagac     2880

ctagcatgcc ctattggcag tgctcaggag ctgcatccca cttttccctg ctctgaatcg     2940

aagtcctagt tccttccttt gattctcctt tggtaggtgg aatcagttaa tgttttgaga     3000

aacctgcctg ggctctgccc ttagtcatga catctcgctg agccagaccc actctgttcc     3060

ttggaaccta gagctggagt gaggagtaga ggtctccggc tattccagaa agaaaagtga     3120

gccacatgca ggctgatgaa tgccgacact tccagaatgt atagaaatag tccctgtcct     3180

ggcctgccac tgaccctgtc tgtattttct cggaggttgt ttttctcctt ctccttccca     3240

ggaaggtctt tgtatgtcga atccagtgca ctcaagtttg gccaagggac tccacagcac     3300

ccagaagact gcatgcctca aggtttatgt cactcctctg ctgggctgtt cattgtcatt     3360

gctgtgttca gggacctttg gaaataaaac ctgttctgtc ccaaataaaa ccagcctgtg     3420

atgttcaagg gactggaata aagtggctta cgacctgaag gattctacag agtgctcaac     3480

tgttcataca tcattcagag tgggagggag ctgggggtgc tgtcccatcc catctgtatg     3540

cccacggtgg atttaataat atataattta taaatcatag cctatggagt ggcccgtaaa     3600

tcagttgact gtgtagctct tgcctggcat taaagcatgt ttttggttta acatgaaaaa     3660

aaaaaaaaaa aaa                                                        3673


<210>  2522
<211>  3586
<212>  DNA
<213>  homo sapiens

<400>  2522
gacggtgctg tccaggggga ggcgggcgga gggaaggcgc tgccgctgct gccgccgcct       60

cgcccgaagc gacacagacg ctgggagcgg ccgaggcgag tgatttcttc tgacttgagc      120

ctgcagtgtg ctgtgagaga tctaccacta gattatctca actttggtct cctgggacca      180

ctcgttgctg acagtcagaa actgaattct tgccgccagg atggggaaac agaacagcaa      240

gctgcgcccg gaggtcatgc aggacttgct ggaaagcaca gactttacag agcatgagat      300

ccaggaatgg tataaaggct tcttgagaga ctgccccagt ggacatttgt caatggaaga      360

gtttaagaaa atatatggga actttttccc ttatggggat gcttccaaat ttgcagagca      420

tgtcttccgc accttcgatg caaatggaga tgggacaata gactttagag aattcatcat      480

cgccttgagt gtaacttcga gggggaagct ggagcagaag ctgaaatggg ccttcagcat      540

gtacgacctg gacggaaatg gctatatcag caaggcagag atgctagaga tcgtgcaggc      600

aatctataag atggtttcct ctgtaatgaa aatgcctgaa gatgagtcaa ccccagagaa      660

aagaacagaa aagatcttcc gccagatgga caccaataga gacggaaaac tctccctgga      720

agagttcatc cgaggagcca aaagcgaccc gtccattgtg cgcctcctgc agtgcgaccc      780

gagcagtgcc ggccagttct gagccctgcg cccaccaatc gaattgtaga gctgcttgtg      840

ttcccttttg attcttcttt ttaacaattt tttttttttt ttgccaaaca atatcaatgg      900

tgatgccgtc ccctgtgcgg tctgatgcgc cttcctccgt gacgccttca gcttcttttg      960

tcgtggatgc ttcgtgggaa tgcccagagc cccagtgtgc ttgtggagag catggacaga     1020

cttcgtggtg ttcattgttt gatgattttt aatcgttact attatttttt tttattctaa     1080

tgtctctgtt ctaaaacgta agactcgggg gttggggcaa aagaagggaa acccatccag     1140

tcctgtgatt ctattgcaag cttcaagggg cttttgtttg aaagacaaaa ctccccacct     1200

gaatctgttg tcacacgtgc cgtaggggtg atggatggca ccggatgctg gattccccaa     1260

gaacaagtta ccctctgggg tgaggctatt ccagcgagct gggacatttc cccatggggg     1320

cccactcccc tctcttcccc agcaggctgt agtttctaag ctgtgaacat ttcaagataa     1380

attaacagag gagaggaaaa agatggctca gctatttttt cacaggttta cactagttga     1440

gctaatatgc gtgtctttgg aaattaaaca caaatggtaa catattccaa aaccagaccc     1500

atcttgttgc ctattgtgat aaaataaaaa gacggctgta tataacatat tgggtaatgc     1560

agaccaaatt aagtgttttg ccttgtttaa atgaaatgca tgtttagtga gcactaatac     1620

aatcttattc cagaagactg tttttagtag cttattgtga agtaagacaa ctataatgaa     1680

tgtctgtctt gtttggaagt catatctgtc tttgcacaaa tgtaccaatc gacaagtata     1740

ttttatatat tccataaaaa tacaaagtaa ccctgactag ggcccaactt taattttgaa     1800

tgcatttcca gagtggccat gcctagaggg cagatgcaga gcaggtggta gtgggacagg     1860

acaattggag cacaggaatg ttaacatgta tgacagggga ccagtagggt ggtttccctc     1920

tcaggcccag cagcccattg acagcattag actggcggca tggtgctttt ctgagcagat     1980

caatactctg cagactcgaa aaaacatcac atacattctt ggaacttccc agtggtttaa     2040

tctatgtgca tggttaggga gccaggtctg gaatattcag tttccctgcc cctgttaaag     2100

aatcagaggt tgggcagtca tcaaattcat cataaagaca tgggcaagtg tgtctgtggt     2160

ttccaaggcc cccctatgga gaatccaaaa gtattttcca ttgccgtgct ctttgaatgc     2220

agacttctat ttccagaagt gacagcacaa gtctgagttg ctgtttggtc tggtgacctc     2280

agacacacta atttgaattg aaagctaaga gtaaaaattt gctggttaca ggcgagtcat     2340

actcttgcaa gtagttagca aagggaggcc caaattctca aggttgttga tggggaactt     2400

gccactaaga gaaggcagag aggtccctag tgggtatatt tgctgccaag ccacttgcca     2460

aagaagagga accacagaaa gagagacatc atgaccagga gaaaaatgtg actagacatg     2520

ctaacctcca ggtttttata tatgacttga gtctgctgta attggcagca gaaatccaaa     2580

tttgtatggt agaccaaaaa gaaccaaatc catagggtga aattttgaga cctagactct     2640

gtaaaaataa tcctagtctt cctccagggg tcagttcctc acagtggttc tgtaccaaaa     2700

cttgccaaat tcctccatgg ccaagtgtta aaatctgtgt ttggaaaata gcgaattaac     2760

ctaagacaca gaaggcagac tgggtgagga gacctagcat gccctattgg cagtgctcag     2820

gagctgcatc ccacttttcc ctgctctgaa tcgaagtcct agttccttcc tttgattctc     2880

ctttggtagg tggaatcagt taatgttttg agaaacctgc ctgggctctg cccttagtca     2940

tgacatctcg ctgagccaga cccactctgt tccttggaac ctagagctgg agtgaggagt     3000

agaggtctcc ggctattcca gaaagaaaag tgagccacat gcaggctgat gaatgccgac     3060

acttccagaa tgtatagaaa tagtccctgt cctggcctgc cactgaccct gtctgtattt     3120

tctcggaggt tgtttttctc cttctccttc ccaggaaggt ctttgtatgt cgaatccagt     3180

gcactcaagt ttggccaagg gactccacag cacccagaag actgcatgcc tcaaggttta     3240

tgtcactcct ctgctgggct gttcattgtc attgctgtgt tcagggacct ttggaaataa     3300

aacctgttct gtcccaaata aaaccagcct gtgatgttca agggactgga ataaagtggc     3360

ttacgacctg aaggattcta cagagtgctc aactgttcat acatcattca gagtgggagg     3420

gagctggggg tgctgtccca tcccatctgt atgcccacgg tggatttaat aatatataat     3480

ttataaatca tagcctatgg agtggcccgt aaatcagttg actgtgtagc tcttgcctgg     3540

cattaaagca tgtttttggt ttaacatgaa aaaaaaaaaa aaaaaa                    3586


<210>  2523
<211>  3729
<212>  DNA
<213>  homo sapiens

<400>  2523
gacggtgctg tccaggggga ggcgggcgga gggaaggcgc tgccgctgct gccgccgcct       60

cgcccgaagc gacacagacg ctgggagcgg ccgaggcgag atcctatcat tattttaaaa      120

ttcctcctcc tccacgaagt ccttcctgat tccttcaaag aaatatcact cctccgaatt      180

cccagagtga tttcttctga cttgagcctg cagtgtgctg tgagagatct accactagat      240

tatctcaact ttggtctcct gggaccactc gttgctgaca gtcagaaaaa gaaaaagaac      300

tctgaaatga aattgaggat ttgaacttca cacagctgtt tgaactgaat tcttgccgcc      360

aggatgggga aacagaacag caagctgcgc ccggaggtca tgcaggactt gctggaaagc      420

acagacttta cagagcatga gatccaggaa tggtataaag gcttcttgag agactgcccc      480

agtggacatt tgtcaatgga agagtttaag aaaatatatg ggaacttttt cccttatggg      540

gatgcttcca aatttgcaga gcatgtcttc cgcaccttcg atgcaaatgg agatgggaca      600

atagacttta gagaattcat catcgccttg agtgtaactt cgagggggaa gctggagcag      660

aagctgaaat gggccttcag catgtacgac ctggacggaa atggctatat cagcaaggca      720

gagatgctag agatcgtgca ggcaatctat aagatggttt cctctgtaat gaaaatgcct      780

gaagatgagt caaccccaga gaaaagaaca gaaaagatct tccgccagat ggacaccaat      840

agagacggaa aactctccct ggaagagttc atccgaggag ccaaaagcga cccgtccatt      900

gtgcgcctcc tgcagtgcga cccgagcagt gccggccagt tctgagccct gcgcccacca      960

atcgaattgt agagctgctt gtgttccctt ttgattcttc tttttaacaa tttttttttt     1020

tttttgccaa acaatatcaa tggtgatgcc gtcccctgtg cggtctgatg cgccttcctc     1080

cgtgacgcct tcagcttctt ttgtcgtgga tgcttcgtgg gaatgcccag agccccagtg     1140

tgcttgtgga gagcatggac agacttcgtg gtgttcattg tttgatgatt tttaatcgtt     1200

actattattt ttttttattc taatgtctct gttctaaaac gtaagactcg ggggttgggg     1260

caaaagaagg gaaacccatc cagtcctgtg attctattgc aagcttcaag gggcttttgt     1320

ttgaaagaca aaactcccca cctgaatctg ttgtcacacg tgccgtaggg gtgatggatg     1380

gcaccggatg ctggattccc caagaacaag ttaccctctg gggtgaggct attccagcga     1440

gctgggacat ttccccatgg gggcccactc ccctctcttc cccagcaggc tgtagtttct     1500

aagctgtgaa catttcaaga taaattaaca gaggagagga aaaagatggc tcagctattt     1560

tttcacaggt ttacactagt tgagctaata tgcgtgtctt tggaaattaa acacaaatgg     1620

taacatattc caaaaccaga cccatcttgt tgcctattgt gataaaataa aaagacggct     1680

gtatataaca tattgggtaa tgcagaccaa attaagtgtt ttgccttgtt taaatgaaat     1740

gcatgtttag tgagcactaa tacaatctta ttccagaaga ctgtttttag tagcttattg     1800

tgaagtaaga caactataat gaatgtctgt cttgtttgga agtcatatct gtctttgcac     1860

aaatgtacca atcgacaagt atattttata tattccataa aaatacaaag taaccctgac     1920

tagggcccaa ctttaatttt gaatgcattt ccagagtggc catgcctaga gggcagatgc     1980

agagcaggtg gtagtgggac aggacaattg gagcacagga atgttaacat gtatgacagg     2040

ggaccagtag ggtggtttcc ctctcaggcc cagcagccca ttgacagcat tagactggcg     2100

gcatggtgct tttctgagca gatcaatact ctgcagactc gaaaaaacat cacatacatt     2160

cttggaactt cccagtggtt taatctatgt gcatggttag ggagccaggt ctggaatatt     2220

cagtttccct gcccctgtta aagaatcaga ggttgggcag tcatcaaatt catcataaag     2280

acatgggcaa gtgtgtctgt ggtttccaag gcccccctat ggagaatcca aaagtatttt     2340

ccattgccgt gctctttgaa tgcagacttc tatttccaga agtgacagca caagtctgag     2400

ttgctgtttg gtctggtgac ctcagacaca ctaatttgaa ttgaaagcta agagtaaaaa     2460

tttgctggtt acaggcgagt catactcttg caagtagtta gcaaagggag gcccaaattc     2520

tcaaggttgt tgatggggaa cttgccacta agagaaggca gagaggtccc tagtgggtat     2580

atttgctgcc aagccacttg ccaaagaaga ggaaccacag aaagagagac atcatgacca     2640

ggagaaaaat gtgactagac atgctaacct ccaggttttt atatatgact tgagtctgct     2700

gtaattggca gcagaaatcc aaatttgtat ggtagaccaa aaagaaccaa atccataggg     2760

tgaaattttg agacctagac tctgtaaaaa taatcctagt cttcctccag gggtcagttc     2820

ctcacagtgg ttctgtacca aaacttgcca aattcctcca tggccaagtg ttaaaatctg     2880

tgtttggaaa atagcgaatt aacctaagac acagaaggca gactgggtga ggagacctag     2940

catgccctat tggcagtgct caggagctgc atcccacttt tccctgctct gaatcgaagt     3000

cctagttcct tcctttgatt ctcctttggt aggtggaatc agttaatgtt ttgagaaacc     3060

tgcctgggct ctgcccttag tcatgacatc tcgctgagcc agacccactc tgttccttgg     3120

aacctagagc tggagtgagg agtagaggtc tccggctatt ccagaaagaa aagtgagcca     3180

catgcaggct gatgaatgcc gacacttcca gaatgtatag aaatagtccc tgtcctggcc     3240

tgccactgac cctgtctgta ttttctcgga ggttgttttt ctccttctcc ttcccaggaa     3300

ggtctttgta tgtcgaatcc agtgcactca agtttggcca agggactcca cagcacccag     3360

aagactgcat gcctcaaggt ttatgtcact cctctgctgg gctgttcatt gtcattgctg     3420

tgttcaggga cctttggaaa taaaacctgt tctgtcccaa ataaaaccag cctgtgatgt     3480

tcaagggact ggaataaagt ggcttacgac ctgaaggatt ctacagagtg ctcaactgtt     3540

catacatcat tcagagtggg agggagctgg gggtgctgtc ccatcccatc tgtatgccca     3600

cggtggattt aataatatat aatttataaa tcatagccta tggagtggcc cgtaaatcag     3660

ttgactgtgt agctcttgcc tggcattaaa gcatgttttt ggtttaacat gaaaaaaaaa     3720

aaaaaaaaa                                                             3729


<210>  2524
<211>  1268
<212>  DNA
<213>  homo sapiens

<400>  2524
gccctctcac cccgctgcct ctaggttctg ggaagatggc gaaggtctca gagctttacg       60

atgtcacttg ggaagaaatg agagataaaa tgagaaaatg gagagaagaa aactcaagaa      120

atagtgagca aattgtggaa gttggagaag aattaattaa tgaatatgct tctaagctgg      180

gagatgatat ttggatcata tatgaacagg tgatgattgc agcactagac tatggtcggg      240

atgacttggc attgttttgt cttcaagagc tgagaagaca gttccctggc agtcacagag      300

tcaagcgatt aacaggcatg agatttgaag ccatggaaag atatgatgat gctatacagc      360

tatatgatag gattttacaa gaagatccaa ctaacactgc tgcaagaaag cgtaagattg      420

ccattcgaaa agcccagggg aaaaatgtgg aggccattcg ggagctgaat gagtatctgg      480

aacaatttgt tggagaccaa gaagcctggc atgaacttgc agaactttac atcaatgaac      540

atgactatgc aaaagcagcc ttttgtttag aggaactaat gatgactaat ccacacaacc      600

acttatactg tcagcagtat gctgaagtta agtataccca aggtggactt gaaaacctcg      660

aactttcaag aaagtatttt gcacaggcat tgaaactgaa caacagaaat atgagagctt      720

tgtttggact ttatatgtcg gcaagtcata ttgcttctaa tccaaaagca agtgcaaaaa      780

cgaaaaagga caacatgaaa tatgctagtt gggcagctag tcaaataaac agagcttatc      840

agtttgcagg tcgaagtaag aaggaaacca aatattctct taaggctgtc gaagacatgt      900

tggaaacatt gcagatcacc cagtcttaag gtttcaaaaa ctctttgaca ttagatttca      960

caactgcaca attgaactta ttggcctgta acttatttac taaatgctca gtgctattta     1020

tatactacag taattttctg ttaagaaggc agttgtaaag aatgtgttta tataaaccta     1080

aaaatgcctt ttactgctaa gtggggagat gggggaaatc catggaagag agatttaaga     1140

cttattgatt gtacatcagt ctcttcatat cacatataca tgtatatata taaaactcta     1200

atgtagtata accttgttaa ataaaccatg atgatttaca aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaa                                                              1268


<210>  2525
<211>  3010
<212>  DNA
<213>  homo sapiens

<400>  2525
agcattgacc aataggagac cgtagtgata gcgacgggga aattcaaacg tgtttgcgga       60

aaggagtttg ggttccatct tttcatttcc ccagcgcagc tttctgtaga aatggaatcc      120

gaggatttaa gtggcagaga attgacaatt gattccataa tgaacaaagt gagagacatt      180

aaaaataagt ttaaaaatga agaccttact gatgaactaa gcttgaataa aatttctgct      240

gatactacag ataactcggg aactgttaac caaattatga tgatggcaaa caacccagag      300

gactggttga gtttgttgct caaactagag aaaaacagtg ttccgctaag tgatgctctt      360

ttaaataaat tgattggtcg ttacagtcaa gcaattgaag cgcttccccc agataaatat      420

ggccaaaatg agagttttgc tagaattcaa gtgagatttg ctgaattaaa agctattcaa      480

gagccagatg atgcacgtga ctactttcaa atggccagag caaactgcaa gaaatttgct      540

tttgttcata tatcttttgc acaatttgaa ctgtcacaag gtaatgtcaa aaaaagtaaa      600

caacttcttc aaaaagctgt agaacgtgga gcagtaccac tagaaatgct ggaaattgcc      660

ctgcggaatt taaacctcca aaaaaagcag ctgctttcag aggaggaaaa gaagaattta      720

tcagcatcta cggtattaac tgcccaagaa tcattttccg gttcacttgg gcatttacag      780

aataggaaca acagttgtga ttccagagga cagactacta aagccaggtt tttatatgga      840

gagaacatgc caccacaaga tgcagaaata ggttaccgga attcattgag acaaactaac      900

aaaactaaac agtcatgccc atttggaaga gtcccagtta accttctaaa tagcccagat      960

tgtgatgtga agacagatga ttcagttgta ccttgtttta tgaaaagaca aacctctaga     1020

tcagaatgcc gagatttggt tgtgcctgga tctaaaccaa gtggaaatga ttcctgtgaa     1080

ttaagaaatt taaagtctgt tcaaaatagt catttcaagg aacctctggt gtcagatgaa     1140

aagagttctg aacttattat tactgattca ataaccctga agaataaaac ggaatcaagt     1200

cttctagcta aattagaaga aactaaagag tatcaagaac cagaggttcc agagagtaac     1260

cagaaacagt ggcaatctaa gagaaagtca gagtgtatta accagaatcc tgctgcatct     1320

tcaaatcact ggcagattcc ggagttagcc cgaaaagtta atacagagca gaaacatacc     1380

acttttgagc aacctgtctt ttcagtttca aaacagtcac caccaatatc aacatctaaa     1440

tggtttgacc caaaatctat ttgtaagaca ccaagcagca ataccttgga tgattacatg     1500

agctgtttta gaactccagt tgtaaagaat gactttccac ctgcttgtca gttgtcaaca     1560

ccttatggcc aacctgcctg tttccagcag caacagcatc aaatacttgc cactccactt     1620

caaaatttac aggttttagc atcttcttca gcaaatgaat gcatttcggt taaaggaaga     1680

atttattcca tattaaagca gataggaagt ggaggttcaa gcaaggtatt tcaggtgtta     1740

aatgaaaaga aacagatata tgctataaaa tatgtgaact tagaagaagc agataaccaa     1800

actcttgata gttaccggaa cgaaatagct tatttgaata aactacaaca acacagtgat     1860

aagatcatcc gactttatga ttatgaaatc acggaccagt acatctacat ggtaatggag     1920

tgtggaaata ttgatcttaa tagttggctt aaaaagaaaa aatccattga tccatgggaa     1980

cgcaagagtt actggaaaaa tatgttagag gcagttcaca caatccatca acatggcatt     2040

gttcacagtg atcttaaacc agctaacttt ctgatagttg atggaatgct aaagctaatt     2100

gattttggga ttgcaaacca aatgcaacca gatacaacaa gtgttgttaa agattctcag     2160

gttggcacag ttaattatat gccaccagaa gcaatcaaag atatgtcttc ctccagagag     2220

aatgggaaat ctaagtcaaa gataagcccc aaaagtgatg tttggtcctt aggatgtatt     2280

ttgtactata tgacttacgg gaaaacacca tttcagcaga taattaatca gatttctaaa     2340

ttacatgcca taattgatcc taatcatgaa attgaatttc ccgatattcc agagaaagat     2400

cttcaagatg tgttaaagtg ttgtttaaaa agggacccaa aacagaggat atccattcct     2460

gagctcctgg ctcatccata tgttcaaatt caaactcatc cagttaacca aatggccaag     2520

ggaaccactg aagaaatgaa atatgttctg ggccaacttg ttggtctgaa ttctcctaac     2580

tccattttga aagctgctaa aactttatat gaacactata gtggtggtga aagtcataat     2640

tcttcatcct ccaagacttt tgaaaaaaaa aggggaaaaa aatgatttgc agttattcgt     2700

aatgtcagat accacctata aaatatattg gactgttata ctcttgaatc cctgtggaaa     2760

tctacatttg aagacaacat cactctgaag tgttatcagc aaaaaaaatt cagtagatta     2820

tctttaaaag aaaactgtaa aaatagcaac cacttatggc actgtatata ttgtagactt     2880

gttttctctg ttttatgctc ttgtgtaatc tacttgacat cattttactc ttggaatagt     2940

gggtggatag caagtatatt ctaaaaaact ttgtaaataa agttttgtgg ctaaaatgac     3000

actaacattt                                                            3010


<210>  2526
<211>  3019
<212>  DNA
<213>  homo sapiens

<400>  2526
agcattgacc aataggagac cgtagtgata gcgacgggga aattcaaacg tgtttgcgga       60

aaggagtttg ggttccatct tttcatttcc ccagcgcagc tttctgtagt ttttttctta      120

gaaatggaat ccgaggattt aagtggcaga gaattgacaa ttgattccat aatgaacaaa      180

gtgagagaca ttaaaaataa gtttaaaaat gaagacctta ctgatgaact aagcttgaat      240

aaaatttctg ctgatactac agataactcg ggaactgtta accaaattat gatgatggca      300

aacaacccag aggactggtt gagtttgttg ctcaaactag agaaaaacag tgttccgcta      360

agtgatgctc ttttaaataa attgattggt cgttacagtc aagcaattga agcgcttccc      420

ccagataaat atggccaaaa tgagagtttt gctagaattc aagtgagatt tgctgaatta      480

aaagctattc aagagccaga tgatgcacgt gactactttc aaatggccag agcaaactgc      540

aagaaatttg cttttgttca tatatctttt gcacaatttg aactgtcaca aggtaatgtc      600

aaaaaaagta aacaacttct tcaaaaagct gtagaacgtg gagcagtacc actagaaatg      660

ctggaaattg ccctgcggaa tttaaacctc caaaaaaagc agctgctttc agaggaggaa      720

aagaagaatt tatcagcatc tacggtatta actgcccaag aatcattttc cggttcactt      780

gggcatttac agaataggaa caacagttgt gattccagag gacagactac taaagccagg      840

tttttatatg gagagaacat gccaccacaa gatgcagaaa taggttaccg gaattcattg      900

agacaaacta acaaaactaa acagtcatgc ccatttggaa gagtcccagt taaccttcta      960

aatagcccag attgtgatgt gaagacagat gattcagttg taccttgttt tatgaaaaga     1020

caaacctcta gatcagaatg ccgagatttg gttgtgcctg gatctaaacc aagtggaaat     1080

gattcctgtg aattaagaaa tttaaagtct gttcaaaata gtcatttcaa ggaacctctg     1140

gtgtcagatg aaaagagttc tgaacttatt attactgatt caataaccct gaagaataaa     1200

acggaatcaa gtcttctagc taaattagaa gaaactaaag agtatcaaga accagaggtt     1260

ccagagagta accagaaaca gtggcaatct aagagaaagt cagagtgtat taaccagaat     1320

cctgctgcat cttcaaatca ctggcagatt ccggagttag cccgaaaagt taatacagag     1380

aaacatacca cttttgagca acctgtcttt tcagtttcaa aacagtcacc accaatatca     1440

acatctaaat ggtttgaccc aaaatctatt tgtaagacac caagcagcaa taccttggat     1500

gattacatga gctgttttag aactccagtt gtaaagaatg actttccacc tgcttgtcag     1560

ttgtcaacac cttatggcca acctgcctgt ttccagcagc aacagcatca aatacttgcc     1620

actccacttc aaaatttaca ggttttagca tcttcttcag caaatgaatg catttcggtt     1680

aaaggaagaa tttattccat attaaagcag ataggaagtg gaggttcaag caaggtattt     1740

caggtgttaa atgaaaagaa acagatatat gctataaaat atgtgaactt agaagaagca     1800

gataaccaaa ctcttgatag ttaccggaac gaaatagctt atttgaataa actacaacaa     1860

cacagtgata agatcatccg actttatgat tatgaaatca cggaccagta catctacatg     1920

gtaatggagt gtggaaatat tgatcttaat agttggctta aaaagaaaaa atccattgat     1980

ccatgggaac gcaagagtta ctggaaaaat atgttagagg cagttcacac aatccatcaa     2040

catggcattg ttcacagtga tcttaaacca gctaactttc tgatagttga tggaatgcta     2100

aagctaattg attttgggat tgcaaaccaa atgcaaccag atacaacaag tgttgttaaa     2160

gattctcagg ttggcacagt taattatatg ccaccagaag caatcaaaga tatgtcttcc     2220

tccagagaga atgggaaatc taagtcaaag ataagcccca aaagtgatgt ttggtcctta     2280

ggatgtattt tgtactatat gacttacggg aaaacaccat ttcagcagat aattaatcag     2340

atttctaaat tacatgccat aattgatcct aatcatgaaa ttgaatttcc cgatattcca     2400

gagaaagatc ttcaagatgt gttaaagtgt tgtttaaaaa gggacccaaa acagaggata     2460

tccattcctg agctcctggc tcatccatat gttcaaattc aaactcatcc agttaaccaa     2520

atggccaagg gaaccactga agaaatgaaa tatgttctgg gccaacttgt tggtctgaat     2580

tctcctaact ccattttgaa agctgctaaa actttatatg aacactatag tggtggtgaa     2640

agtcataatt cttcatcctc caagactttt gaaaaaaaaa ggggaaaaaa atgatttgca     2700

gttattcgta atgtcagata ccacctataa aatatattgg actgttatac tcttgaatcc     2760

ctgtggaaat ctacatttga agacaacatc actctgaagt gttatcagca aaaaaaattc     2820

agtagattat ctttaaaaga aaactgtaaa aatagcaacc acttatggca ctgtatatat     2880

tgtagacttg ttttctctgt tttatgctct tgtgtaatct acttgacatc attttactct     2940

tggaatagtg ggtggatagc aagtatattc taaaaaactt tgtaaataaa gttttgtggc     3000

taaaatgaca ctaacattt                                                  3019


<210>  2527
<211>  3409
<212>  DNA
<213>  homo sapiens

<400>  2527
taagaaacga cacacagatt aggcagtgct actcttctta aatctctcat ttgtttccta       60

ggttccctgg ttgtgaaaat acatgagata aatcatgaag gccactatca tcctccttct      120

gcttgcacaa gtttcctggg ctggaccgtt tcaacagaga ggcttatttg actttatgct      180

agaagatgag gcttctggga taggcccaga agttcctgat gaccgcgact tcgagccctc      240

cctaggccca gtgtgcccct tccgctgtca atgccatctt cgagtggtcc agtgttctga      300

tttgggtctg gacaaagtgc caaaggatct tccccctgac acaactctgc tagacctgca      360

aaacaacaaa ataaccgaaa tcaaagatgg agactttaag aacctgaaga accttcacgt      420

tgtctacctt cataacaaca atatctctgt agttggatca agtgacttct gcccacctgg      480

acacaacacc aaaaaggctt cttattcggg tgtgagtctt ttcagcaacc cggtccagta      540

ctgggagata cagccatcca ccttcagatg tgtctacgtg cgctctgcca ttcaactcgg      600

aaactataag taattctcaa gaaagccctc atttttataa cctggcaaaa tcttgttaat      660

gtcattgcta aaaaataaat aaaagctaga tactggaaac ctaactgcaa tgtggatgtt      720

ttacccacat gacttattat gcataaagcc aaatttccag tttaagtaat tgcctacaat      780

aaaaagaaat tttgcctgcc attttcagaa tcatcttttg aagctttctg ttgatgttaa      840

ctgagctact agagatattc ttatttcact aaatgtaaaa tttggagtaa atatatatgt      900

caatatttag taaagctttt cttttttaat ttccaggaaa aaataaaaag agtatgagtc      960

ttctgtaatt cattgagcag ttagctcatt tgagataaag tcaaatgcca aacactagct     1020

ctgtattaat ccccatcatt actggtaaag cctcatttga atgtgtgaat tcaatacagg     1080

ctatgtaaaa tttttactaa tgtcattatt ttgaaaaaat aaatttaaaa atacattcaa     1140

aattactatt gtatacaagc ttaattgtta atattcccta aacacaattt tatgaaggga     1200

gaagacattg gtttgttgac aataacagta catcttttca agttctcagc tatttcttct     1260

acctctccct atcttacatt tgagtatggt aacttatgtc atctatgttg aatgtaagct     1320

tataaagcac aaagcataca tttcctgact ggtctagaga actgatgttt caatttaccc     1380

ctctgctaaa taaatattaa aactatcatg tgacttcatg taatcaggct gaacatttct     1440

acaattacta gatgtattag acgtaagtat tttctttagt taaaccaccc atgttagaaa     1500

tgttttctgt agaatttata aacaactatc aatgcagaca atttaataag cctggggatg     1560

atttacttac agtaaacatt tatcaaattg tacatttgtg ctatcaacaa ttaataagca     1620

aatatgtgaa aatagtttct gtcttctatg aagttagata tttgatggtt aaaaccccta     1680

taaatcatag tttcatatgg gaaaaaataa ttgaaataca gtgtaaattt aaataattta     1740

ttaagtatag caaataattg aaatatggtg gactaaattt tgtcatagaa atatgtgcaa     1800

gttatagtag tggctcacat gagaggtaat caattctgct aatagtagca gaatgagtgc     1860

agtggaacat gaaaaacttg aggagataac agttgaggtg ggtttccata gatgcataat     1920

agttcaagag caagatttgg tggggaggca ctattcaaga cagggactaa gttcaaaatc     1980

caagacgtat gctgggacac acctctgaca ggttggcata aaggaggctt aatcaaacta     2040

tttttcttct tctgaaacag aagcaataat tttcatttac atttgacata tcccgaggta     2100

atattaacat tagggaaagt tactcttttc catctttcca cattcttgca ggaccataaa     2160

atctgaattt tccagtattt ttaataagag ggaagaaacc tctctttttc ttctcttttt     2220

catctcccaa gagatcctcc tctcatgact acagttgaat aggtggtttc tattggaaga     2280

cattcaggaa ttcaaggtgc atgtccataa atggactttt tttgttgttg ttcagagctg     2340

gaccttgaat gatgcatcct tctctctgtt gtaaccatga ataatgcacc cttcatgcta     2400

tagcctttaa cgattcaccc ttcttattgt aaccttgaat gattcaccct ttatggtgta     2460

gccttgagtg acgcaccctt catgttgtag ccttcaatga tgcacactcc atgttatagc     2520

cttgaatgat atacccttta tgctgcagcc tttctcttat ggggaaaagc ctgcagatat     2580

cctgctgctt aactgacaag tgtggtgaga aataagtaga aatctaaaga ggggaagacc     2640

attttggaca cttatctgca aggcagatcc aacacacttt tccagtagtc aagctacttc     2700

taattttgtt cagtatcaaa atgagaaaca ggcctgattc tccagcactc ttgtcaacac     2760

aacttccccc catatttata tatatacaca cacatatata tctttatata tatacacaca     2820

tatatatctt tatatatata tatttatata tatatctttt tgcatatata catatatatg     2880

tatctttatt tcctttgaaa taaagataaa tatagctgat ttctttggct tcgacactta     2940

ctatttgcat gactaaggga agctagttaa cctttctgtg actcatttcc ttgtccataa     3000

aatgggaata ttaattgtac atgtcttatg gattggtgtg tgaattcagt tagcgagtgt     3060

agaatataac ttatagatca aagtagagta aatggaaagg gctcaactat ggtgttgcta     3120

ctgccattgt tattacaggc acacagttcg agctataatc atttcaaggg aaattcttat     3180

gtgtcagttc tggatcgagg tctgagattc tgcatttcaa acaaacttcc aggaatgctg     3240

ctgcttcttg gtccacactt ggagaaataa gtcagcagag agtcctctcg tttcctattg     3300

taccatgtct gtcttttgtc tcctgcttat tggcctctgt aaggaactca cagctgctat     3360

aataaagtac caaaaactgg gtggcttaaa acaaaaaaaa aaaaaaaaa                 3409


<210>  2528
<211>  10981
<212>  DNA
<213>  homo sapiens

<400>  2528
atggtggagc cagggcaaga tttactgctt gctgctttga gtgagagtgg aattagtccg       60

aatgacctct ttgatattga tggtggagat gcagggcttg caactccaat gcctaccccg      120

tcagttcagc agtcagtgcc acttagtgca ttagaactag gtttggagac cgaagcagca      180

gttcctgtta aacaagaacc agagactgta cctactccag cactattaaa tgtgaggcag      240

cagcctccat ctactacaac atttgtgctg aatcaaataa atcatcttcc acccttggga      300

tctacaattg taatgactaa aacaccacct gtaacaacca acaggcaaac catcacttta      360

actaagttta tccagactac tgcaagcaca cgcccgtcag tctcagcacc aacagtacga      420

aatgccatga cctctgcacc ttcaaaagac caagttcagc ttaaagatct actgaaaaat      480

aatagtctta atgaactgat gaaactaaag ccacctgcta atattgctca gccagtagca      540

acagcagcta ctgatgtaag caatggtaca gtaaagaaag agtcttctaa taaagaagga      600

gctagaatgt ggataaacga catgaagatg aggagttttt ccccaaccat gaaggttcct      660

gttgtaaaag aagatgatga accagaggaa gaagatgaag aagaaatggg tcatgcagaa      720

acctatgcag aatacatgcc aataaaatta aaaattggcc tacgtcatcc agatgctgta      780

gtggaaacca gctctttatc cagtgttact cctcctgatg tttggtacaa aacatccatt      840

tctgaggaaa ccattgataa tggctggtta tcagcattgc agcttgaggc aattacatat      900

gcagcccagc aacatgaaac tttcctacct aatggagatc gtgctggctt cttaataggt      960

gatggtgccg gtgtaggaaa aggaaggacg atagcaggaa tcatctatga aaattatttg     1020

ttgagtagaa aacgagcatt gtggtttagt gtttcaaatg acttaaagta tgatgctgaa     1080

agagatttaa gggatattgg agcaaaaaac attttggttc attcgttaaa taagtttaaa     1140

tacggaaaaa tttcttccaa acataatggg agtgtgaaaa agggtgttat ttttgctact     1200

tactcttcac ttattggtga aagccagtct ggcggcaagt ataaaactag gttaaaacaa     1260

cttctgcatt ggtgcggtga tgacttcgat ggagtgatag tgtttgatga gtgtcataaa     1320

gccaaaaact tatgtcctgt tggttcttca aagccaacca agacaggctt agcagtttta     1380

gagcttcaga acaaattgcc aaaagccaga gttgtttatg ctagtgcaac tggtgcttct     1440

gaaccacgca acatggccta tatgaaccgt cttggcatat ggggtgaggg tactccattt     1500

agagaattca gtgattttat tcaagcagta gaacggagag gagttggtgc catggaaata     1560

gttgctatgg atatgaagct tagaggaatg tacattgctc gacaactgag ctttactgga     1620

gtgaccttca aaattgagga agttcttctt tctcagagct acgttaaaat gtataacaaa     1680

gctgtcaagc tgtgggtcat cgccagagag cggtttcagc aagctgcaga tctgattgat     1740

gctgagcaac gaatgaagaa gtccatgtgg ggtcagttct ggtctgctca ccagaggttc     1800

ttcaaatact tatgcatagc atccaaagtt aaaagggttg tgcaactagc tcgagaggaa     1860

atcaagaatg gaaaatgtgt tgtaattggt ctgcagtcta caggagaagc tagaacatta     1920

gaagctttgg aagagggcgg gggagaattg aatgattttg tttcaactgc caaaggtgtg     1980

ttgcagtcac tcattgaaaa acattttcct gctccagaca ggaaaaaact ttatagttta     2040

ctaggaatcg atttgacagc tccaagtaac aacagttcgc caagagatag tccttgtaaa     2100

gaaaataaaa taaagaagcg gaaaggtgaa gaaataactc gagaagccaa aaaagcacga     2160

aaagtaggtg gccttactgg tagcagttct gacgacagtg gaagtgaatc tgatgcctct     2220

gataatgaag aaagtgacta tgagagctct aaaaacatga gttctggaga tgatgacgat     2280

ttcaacccat ttttagatga gtctaatgag gatgatgaaa atgatccctg gttaattaga     2340

aaagaccaca agaaaaacaa agagaaaaaa aagaagaaaa gtatagatcc agattctatt     2400

caaagtgcct tattagcatc aggtcttgga tcaaaacgac ctagtttttc atctacacca     2460

gttatctcac ctgctcctaa cagtacacca gctaacagta acaccaacag taacagtagc     2520

cttataacaa gtcaggatgc tgtggaaagg gctcagcaga tgaagaaaga cctgcttgat     2580

aagctagaaa aattagctga agacctcccc cctaataccc tggatgaact tatcgatgaa     2640

cttggtggcc ctgagaacgt tgctgagatg actggccgca agggacgggt tgtgagcaat     2700

gatgatggaa gcatatctta tgagtcaaga tctgaacttg atgtgcctgt ggaaatacta     2760

aacatcacag aaaaacaacg atttatggat ggagataaga atattgctat catctcagaa     2820

gctgccagct cgggtatttc attacaagca gataggagag ctaaaaatca aaggcgaaga     2880

gttcatatga ctttagaatt accttggagc gctgatagag caattcaaca gttcggacgt     2940

actcatagat caaaccaagt tactgctcct gagtatgtct ttctgatatc tgaactggca     3000

ggagaacaaa gatttgcatc tattgttgct aaaagacttg agagtttggg ggcacttaca     3060

catggtgata gaagggcaac agaatctaga gatctgagca ggttcaactt tgataataag     3120

tatggaagaa atgctttaga aattgtcatg aaatccattg taaacttgga ttctcctatg     3180

gtatcaccac ctccagacta tcctggagaa ttttttaaag atgttcgaca aggactgata     3240

ggcgttggcc tgataaatgt agaagatcgc tcgggaattc ttactctcga taaagattat     3300

aacaacatag gaaaattctt aaatagaatt ttaggcatgg aggtgcatca gcagaatgcg     3360

ttatttcagt attttgcgga cacacttact gcagttgttc aaaatgccaa aaaaaatgga     3420

agatatgata tgggaatctt agatcttggt tctggagatg aaaaagtgcg gaaaagtgat     3480

gttaaaaagt ttctgactcc aggatattca acctctggcc acgtagaatt atacacaatt     3540

agtgtagaga ggggaatgtc atgggaggaa gctaccaaga tttgggctga gctgacagga     3600

ccagacgatg gcttttactt gtcattgcaa ataaggaaca acaagaaaac tgccatctta     3660

gttaaagaag tgaatcctaa aaagaaactt ttcttagttt atcgaccaaa tactgggaag     3720

cagctcaaat tagaaattta tgctgatcta aaaaagaaat ataagaaggt cgtctcagat     3780

gatgccctga tgcactggtt agatcagtat aattcatctg cagatacttg tactcatgct     3840

tattggcgcg gcaattgcaa aaaagcaagc ttggggctag tttgtgaaat aggtcttcgt     3900

tgccgtacat attatgtatt atgtggttca gtgctgagtg tctggacaaa agttgagggt     3960

gttctagcat ctgtcagtgg cacaaacgtg aagatgcaga tcgtgcggct aagaacggaa     4020

gatgggcaac ggattgtagg tttgatcatt ccggcaaatt gtgtgtctcc tcttgtaaat     4080

ctcctatcaa cttcagacca gtctcaacag cttgcggtcc aacagaaaca gctatggcaa     4140

cagcatcacc ctcagagcat caccaacttg agcaacgcat gaagaacaga caggtttcaa     4200

catggatgga tctgaaatgc tgttgaagca tatcatttgc ataaaaatca gggacagttt     4260

ccaaagaatt atatattttt ttcagttgtg ctctctagtt agtttttttg ggagtaagga     4320

caaacctgga atagatagca aaactgaaaa tcagcagtgc tgatggtggt acatatgtct     4380

ttcctttagc ttctcccctg ataattccca tctgctttta cttcgggtga gcagaggggg     4440

atgtgtgtgt gcgtgtgtgt cagtctgttt gtgagtgtgt taaaggctac agaccacagt     4500

tggtttaaaa tgcttggaac ttcccaaact ggctttactt tatgtttata cagtgctcag     4560

ggttaacgca gtacatccat gccattgctg tgggaggtat ccccggatgc atgtgttttg     4620

agtctataaa tatagaaaat atatattggt ttctttttcc aacttaatag gtttattaaa     4680

gcatgaaatg aaaggttgca tatcatgcat tcaggttatt ttctaatttt tgttctgaca     4740

gtgcatgtct ttggaagcat gctgaaacaa gattaacaca ggagtcgagt aacagagaga     4800

aacatttgtt agatgtacag cattggttat tgcattttta tagtgtttat acctgggtat     4860

tgcttcaaac cctgcagacc cctccttccc cttctccctg ccctgggttt ctggtcaagg     4920

taatgaatac atacattttt ctgtgataaa actcttaaaa gttaatttta atgtattaat     4980

agtattccta atgtgtgctg cagaaatggc tatgagcctc ttaaatttac atttgcaact     5040

taaaggtagt tttagaagga agtacaaatt ggctttcatc ttgcaaacaa tcgtttttta     5100

cttcattatc ttaatttgct ttgtcactca taaaaaggaa accatacctg agttgtagac     5160

aatgaggaaa cacttgaggc ttctgctgtg tgttcttttg ttattgttgt tattgttgtt     5220

actcagtaac ttgaatattg tttaatgtgt tgtaagacgt agagtttatc tcaagctgtt     5280

aaaaatggta atgtacaaat gtgaatagac acttatctat ataatatggg taagttttgt     5340

ttcgcctata atagatgttt ataaaaacaa gtgaggggac agttggtctt tttatctttt     5400

ctttcttttt ctttcttttc tttttttctt tttttttttt tttttttttt tttttgcttc     5460

cacaggttgc actattgaaa aatcgagatt gtataaacct ggtaaaaagc tgcaagatgc     5520

caaaatcttg tagatgtcaa ataaaaagtt attatactaa caagaagtgg actcttgttt     5580

aggccctcac tggtgacctt cagaagtagt ctgtgacggg gactcagcag aatttgtgtg     5640

ttgtctcagc attccaggta gccttatagt ttggcttaaa acttatccct aaaatgtaag     5700

atggcattga gggaaagggt ataatgatag tacttctgaa tgttttttaa gttgaattgt     5760

ttgtaaactt cttgcagaat tgggtgagat gtgtgttaaa actgacaaac ctggctgaaa     5820

gcttagggcg ttcatcctct tgtgtctcct ttagcctgag tttggttatg tcaagcttac     5880

cgtaagtttt cttaggattt atttattctt ggtgcctaaa agaataaatt gaaagtactt     5940

tctgttcttt ggcacatttt gcccagcgga tgcaacttct atcctcagtc cagttcatat     6000

atctcaggca gtgatccatt ttgtatcagc cagtttccct tgttagggcc gctagacccg     6060

gctggcagcc aagagcagca ctctccccac cttcagcaga acttctcagc tcatgtgtgt     6120

gtttttaaaa gcagtaggca gcttccatca gcaatggaag tgtcccccac tccagtggtg     6180

gaggtgcagt cgctggacct gaggaagtgg ggaagcatta caaaccctcc tgcagtaaga     6240

atggcagagt tgggaaggat cttctctcgc aggctgttgg cccaactcct cttttctgtg     6300

tatgagggca tcttagtttt ttatggcgtt ttcaaagcag catatgagga ttcttagcat     6360

gcagctaagt gacaaccccc atggcctatg atgtaatgtt tgctctggac tagccatctt     6420

gataaatagg agtgtatgta tcttaggttc tttgtagaac agctattttt ttttctcatt     6480

aaaaaggcct ctgaaagccc tctcaaaatg gacctcacaa aggcaaccag tgtgaatgga     6540

tgggagctgg ggtgctgcat gcccaggctg gtcatggtgt gtgcagcacc cagagagttg     6600

cacccacccc ttcttcaggt ggacatccga cctttacact gtggtcttgc aaaaatcagc     6660

gagttagttt ggccgccctg tgaagcttca gcattcaagg tcctcttctg ttaaaaccca     6720

actcgtagcc gggcgtggtg gctcactcct ataatcccag cacttcggga ggccaaggca     6780

ggtgcatcac ttgaggccag gagttcgaga ccagcctggt ccacatggca aaaccccatc     6840

tgtaccaaaa aatacaaaaa atttgccgct gacttctgta aaataggtcc attcattgca     6900

ggatctaaat gccacacctg aattcagagg ccttgtttaa ttaaccccat gtccactttg     6960

cctctgcaat gcctttttct ttttagcaat atggctctga gcacaaagat ttggttggaa     7020

atcatgttcg tgttttcaga gtttacagcg tcaattgtac tgaaaaccac ttccagagtc     7080

taaagcagct cagatgttat ctctggggga attagtgttc ccctcattta gcaacctcca     7140

taccacaagg tctctgtctg tagttactgg gattatccag atacactatc aatgatacaa     7200

attcatagga gtattaatgc atttctttaa acacaacttg attaagaagc aaatatgtta     7260

agcagttttc tttttctgct gctaaattac agttagacac ttcagtatct tctctttaca     7320

tgtgtatata aattagtaag aacctgcatc caaagcaatg tagtgtgtgt atgtatctat     7380

atatatttat tctaactcag cacttcagaa gcctttttga gttacaacaa tattttagtt     7440

tgcctcatct gtagaggtaa aatttctata ttaccaagct ccagaggaat atgatatttt     7500

acaggcacaa ttttctggct gtagtccctg gggcattcat ttgctggcct ccatgggatg     7560

ctgttagaac aattgttagc cggcaagaga agaaaggcta ccaggacagc atttataatt     7620

gtagaatggg agccttcttc cctctcccct ccactttcat tttagcatga gataaaaaaa     7680

tagattggaa atgattgttg catctcactt catggaagta ggggcagaag ttccctctgg     7740

atccttttct tgacaagcag tcaagaggaa ggtccccata cacatgtacc tgtgtgatac     7800

ttggtagttt ctaagaatgg tgctacataa gcgttgctgt taggctggga tcctattaat     7860

gaacgtttga ttagttcagg cctcccaatg gcaaaggcag acaccgtgga gatggacatt     7920

tactgactcc ccttctgtgt ggcttcggtc tccctggcta acaccacacc tgtgcgtact     7980

gcgctcggcc cactttgctg cagaaacgta gcaagcgttt catgtcaggg ctacagctga     8040

gagcaaaaac tgcaaaaaaa aaaaaaaatg tctcattgaa tgccagttgt ctgatacaaa     8100

tgcagtgtct tttaagtgac agaaacacac ctaaatacct gcaactcaag ctcgctagca     8160

tttttttttt gagtacttga gataaaatcc aaaacccacc ctctaatttt gtgctgtatt     8220

tatatatatg tacataaatg tatatataga gaaatgttga gttcttctgg attctgaatg     8280

taaataattc ttgtaaattg ggactctgcc cacctgtttc tcccttttcc ctcttccctt     8340

cagctctatt tattcttttc ttgactttcc catatggggc atcttatgac tttttttttt     8400

tttttttttt aagaaaagta tggaaaactt ttcatttaga aaagtatttg ttcctgtatt     8460

ttagaattca gttttgcatc tttgctgtag aattcctgtt ttgtgttaat gttttttact     8520

atgtcttatt gtgttgtgtg caatgcattg tactgggggg atgcacttga gtgccatttc     8580

tgatactgtc attgtatgac tgctgatgct cgtttatgtt gttctttgga agctatagtg     8640

agcctgatgt tttcacattt taaaaaatgc ttcctgagac ttctttaagc tcctctaact     8700

tcttcagtgc atttgggatc aaacttagct cttagatcag caaacctgac ttgcttctac     8760

ttttgcaatt tttcaggcct taccatattt cttatctctg tcttcccacc tgataggaaa     8820

atcttgcaga tttgaaacag tggtttctgg cctgctgctg cagcaaattc cctatgttta     8880

tttaagaagt cgggcctatg cttttaacct acaaatgatg agtaatttac ttgcaatgaa     8940

cacaggtagc ctgctgctgt ttataacctg ttgaggatat ttatagcagg caggaggcag     9000

gcctagtgtg ttattgacag gtgactttag agaatgtaca ttggccgggt gcggtggctc     9060

acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcatgagg tcaggagatt     9120

gagaccatct cctggctaac acggtgaaac cccgtctcta ctaaaaatac aaaaaaaaaa     9180

aaaacttagc caggcgtggt ggcgggtgcc tgtagtccca gctactcagg aggctgaggc     9240

aggagaatgg catgaacctg ggaggcagag cttgcagtga gcccagatcg cgccactgca     9300

ctccagcctg ggcaacagac cgagactccg tctcgaaaaa aaaaaaagag agagaatgta     9360

cattaaggaa caattgtcct ccaaaagaga gccaagcaac tgctctggag cctcctaggc     9420

tgactctgct ggagggtgag acaagcagat tcccattgca gcactggtcc ctggggtacc     9480

ctgaacggct gtgctctcca cccttgtatc ggtgagtgga tcttgtctac atcagccgta     9540

agcctagaag cagagcggga tcgaggcgtt tttaataatt cgagttggga agacccggat     9600

ggttcatcaa aatgatggtg ttgagcaccc gggaggcaga cattgggtat ttgttcacaa     9660

ttttgcacct gtaagaaaat gttcctttat aactttcaag gattgccgtg agcgtctttg     9720

gggccttttc attcatgtac aagtttcatt cattactatt caacttggta gacttggtga     9780

aaaatgtaaa agcattctgt atttggatca gtcttgggaa ctaaatttgt cgtgaattgg     9840

ggcctgtcac agattgcctc cagtgtgcat cctccacgca gaccctcctt gctcagtctc     9900

cctctggcgc ccatggggaa gccgtgctgt ggttggcagt gcggccatct gggctgccgc     9960

aacgtggcag ggcaccgtcc agcaagactg ccccttagtg cagggctaag caaggaaaag    10020

aagaagccca aaaaggcggg ttctttttga tacttgtaat tcaggcgtcc tccagagtga    10080

aggccactct gcaggcccct ggtgagaacc tgtctggctt ttccactgcg ggcccctaac    10140

cagtaccctg cccttgtggc ccatttgtgc ctgggcagat gtttctggcc agcagacact    10200

gaaggccttt ttgctgtgac agtatttatg gcactgaaga ggataaagaa gcttgagccc    10260

tctttctgac tcccacttta tggggcagag agagcttttt ttctacatag cacattgcag    10320

tctcaccgct atcagaaaaa tatcctgttc atggtttata ctgaatttgc aaactactga    10380

tatgattttt caataaccac ttgtatcttc catcatccat gagaggtggg aagaggtaca    10440

ctgtatctct gcaataaaac tttggccagg ttctacctcc tctgagcaaa ggatactttt    10500

ctatgtaggt gtagatggtt ctcctttact aatctgacat ggtgcatctg gagacaacat    10560

ctgatgggat ccaaagacaa cttgaaacaa aggtggatgt cagctcttgg tgtgttttca    10620

tttggttctc ttttttaaat ctcccttttg ttatcgctcc tgttgtagcg tgtccatcag    10680

tgtgtgaagg gtgcgccctg ttccaatgat actgcattgc tgcatccagc ctttcgtggg    10740

agcacggtac caagcgtccg gaattgatta tcccaatcat ttttgatatg taactgaaaa    10800

atttggtctc atgcaataaa aatgtactgg ctgcatttta gcaaggttta tttactcttg    10860

caagtaaaaa cgatcaaccg tgaagcgtaa caaattctgt atttagtttt tttttctgtt    10920

gtggtggttt ttgttttgtt ttttgttttt gtaagattct aaataaatta aatacgagtc    10980

a                                                                    10981


<210>  2529
<211>  3359
<212>  DNA
<213>  homo sapiens

<400>  2529
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtaatg     1560

ggactcctga ccaaccacgg tggggtacct catcagcccc agactgatta cgcgctctcc     1620

cctctcaccg ggggtctgga acctaccacc acggtgtcgg ccagctgcag tcagagacta     1680

gaccatatga agagcttgga cagtctgcca acatctcagt cctactgtcc acccacctat     1740

agcaccacag gctacagtat ggaccctgtc acaggctacc aatatgggca gtatggacaa     1800

agtgcctttc attatctcaa gccagatatc gcgtaagtga actgtccact tggagctaaa     1860

actggccctg tttctggtct tcgcagccta gatatgaaga atctgctctg aaaacaaaaa     1920

aaaattaccc ttttgttggg gggggtgggg cagtggtccc aataggagac aaaggagagt     1980

gattgatttt cttcctccaa tagttggttt caaatccttt tgaacacgtt cgacaaaagc     2040

agtggagaag aggaagacct ggagcaataa aagacaaatg caacatttta aggcaatggt     2100

ttcacatggt tacatatcaa aacatcccaa ttctttagtg ctgatcatcg aggagctaga     2160

acattccatt tgcttgtgtg cgtgcgtgcg tgtgtgtgtg tgtgtgtgta ttgagattta     2220

cccagactgg tttgggcaag cagactgttc taaaatataa tagaataccc taaagtataa     2280

catgtcgatg ttcgatgctg atacttctac aactttaaaa ctgctcattt catgaagcaa     2340

gaatggagga atccttgact cttacacact ggaaattgaa ataaagataa atgcaaccat     2400

ttttaggaag ctagactagc tgtaaaggac ctcctaaata aattatttgt tactgtatcc     2460

tcatttgtaa tctagttgtc aataaatggc ccggacatgt cttgctaaca ggatatgggc     2520

taccaggaag aaggacttgt ttccctttcc tgtgtgggga gaggtgtgtg acgtttttcc     2580

agttcacatt tatttggtag cccacctggg ttggaggaag ggcacggtgg agagaaagtg     2640

acatgcattc acatatctgc ttatcagtgt gcaatactgt gtacctcatg gatgctttgg     2700

caatgcccaa ggcgatataa gcaaaatcag aagtatattt ttgcaggtgc ttttattttc     2760

acagcccata attcatagtg atagagtgca gtgatgtttg ccatttgctg gacaaccaac     2820

acccgggttg ctcctttgat tagagaccag atcagataat tatgctttta aactgattac     2880

gtttacattc ttctcttttc tatgaaaggc agggcaagaa cagaagtgtt cacatggctc     2940

tcatgtactt ttaaattata caatgatatc caatattaaa agattatagg aactgaggtt     3000

tacatacgtt tgtgtggtga cattttagaa tgtcaataaa tttgcttttt gagatgttga     3060

gaggaacaag aaggtggaag gcagtgttat ttatttcttt ctattcttgg aaccacgaat     3120

gaggtaggca caaatacatt ccttttagag ttaagaacta tgacgtagcg agttagtgag     3180

actagacata gtaccgaatt tagttcatgc attggtctta gagggtgatg gaacaagaga     3240

agtactatct ttgtgttgca gcctcaacca acaacaatgt gttgtaaaaa tgtctttcat     3300

gtaaaaagtg cagtaaatat ttactattta taatgaataa acagttatga aaacttgaa      3359


<210>  2530
<211>  3188
<212>  DNA
<213>  homo sapiens

<400>  2530
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtaatg     1560

ggactcctga ccaaccacgg tggggtacct catcagcccc agactgatta cgcgctctcc     1620

cctctcaccg ggggtctgga acctaccacc acggtgtcgg ccagctgcag tcagagacta     1680

gaccatatga agagcttgga cagtctgcca acatctcagt cctactgtcc acccacctat     1740

agcaccacag gctacagtat ggaccctgtc acaggctacc aatatgggca gtatggacaa     1800

agtgcctttc attatctcaa gccagatatc gcttggtttc aaatcctttt gaacacgttc     1860

gacaaaagca gtggagaaga ggaagacctg gagcaataaa agacaaatgc aacattttaa     1920

ggcaatggtt tcacatggtt acatatcaaa acatcccaat tctttagtgc tgatcatcga     1980

ggagctagaa cattccattt gcttgtgtgc gtgcgtgcgt gtgtgtgtgt gtgtgtgtat     2040

tgagatttac ccagactggt ttgggcaagc agactgttct aaaatataat agaataccct     2100

aaagtataac atgtcgatgt tcgatgctga tacttctaca actttaaaac tgctcatttc     2160

atgaagcaag aatggaggaa tccttgactc ttacacactg gaaattgaaa taaagataaa     2220

tgcaaccatt tttaggaagc tagactagct gtaaaggacc tcctaaataa attatttgtt     2280

actgtatcct catttgtaat ctagttgtca ataaatggcc cggacatgtc ttgctaacag     2340

gatatgggct accaggaaga aggacttgtt tccctttcct gtgtggggag aggtgtgtga     2400

cgtttttcca gttcacattt atttggtagc ccacctgggt tggaggaagg gcacggtgga     2460

gagaaagtga catgcattca catatctgct tatcagtgtg caatactgtg tacctcatgg     2520

atgctttggc aatgcccaag gcgatataag caaaatcaga agtatatttt tgcaggtgct     2580

tttattttca cagcccataa ttcatagtga tagagtgcag tgatgtttgc catttgctgg     2640

acaaccaaca cccgggttgc tcctttgatt agagaccaga tcagataatt atgcttttaa     2700

actgattacg tttacattct tctcttttct atgaaaggca gggcaagaac agaagtgttc     2760

acatggctct catgtacttt taaattatac aatgatatcc aatattaaaa gattatagga     2820

actgaggttt acatacgttt gtgtggtgac attttagaat gtcaataaat ttgctttttg     2880

agatgttgag aggaacaaga aggtggaagg cagtgttatt tatttctttc tattcttgga     2940

accacgaatg aggtaggcac aaatacattc cttttagagt taagaactat gacgtagcga     3000

gttagtgaga ctagacatag taccgaattt agttcatgca ttggtcttag agggtgatgg     3060

aacaagagaa gtactatctt tgtgttgcag cctcaaccaa caacaatgtg ttgtaaaaat     3120

gtctttcatg taaaaagtgc agtaaatatt tactatttat aatgaataaa cagttatgaa     3180

aacttgaa                                                              3188


<210>  2531
<211>  6969
<212>  DNA
<213>  homo sapiens

<400>  2531
aatattttgt gtgagagcga gcggtgcatt tgcatgttgc ggagtgatta gtgggtttga       60

aaagggaacc gtggctcggc ctcatttccc gctctggttc aggcgcagga ggaagtgttt      120

tgctggagga tgatgacaga ggtcaggctt cgctaatggg ccagtgagga gcggtggagg      180

cgaggccggg cgccggcaca cacacattaa cacacttgag ccatcaccaa tcagcatagg      240

aatctgagaa ttgctctcac acaccaaccc agcaacatcc gtggagaaaa ctctcaccag      300

caactccttt aaaacaccgt catttcaaac cattgtggtc ttcaagcaac aacagcagca      360

caaaaaaccc caaccaaaca aaactcttga cagaagctgt gacaaccaga aaggatgcct      420

cataaagggg gaagacttta actaggggcg cgcagatgtg tgaggccttt tattgtgaga      480

gtggacagac atccgagatt tcagagcccc atattcgagc cccgtggaat cccgcggccc      540

ccagccagag ccagcatgca gaacagtcac agcggagtga atcagctcgg tggtgtcttt      600

gtcaacgggc ggccactgcc ggactccacc cggcagaaga ttgtagagct agctcacagc      660

ggggcccggc cgtgcgacat ttcccgaatt ctgcaggtgt ccaacggatg tgtgagtaaa      720

attctgggca ggtattacga gactggctcc atcagaccca gggcaatcgg tggtagtaaa      780

ccgagagtag cgactccaga agttgtaagc aaaatagccc agtataagcg ggagtgcccg      840

tccatctttg cttgggaaat ccgagacaga ttactgtccg agggggtctg taccaacgat      900

aacataccaa gcgtgtcatc aataaacaga gttcttcgca acctggctag cgaaaagcaa      960

cagatgggcg cagacggcat gtatgataaa ctaaggatgt tgaacgggca gaccggaagc     1020

tggggcaccc gccctggttg gtatccgggg acttcggtgc cagggcaacc tacgcaagat     1080

ggctgccagc aacaggaagg agggggagag aataccaact ccatcagttc caacggagaa     1140

gattcagatg aggctcaaat gcgacttcag ctgaagcgga agctgcaaag aaatagaaca     1200

tcctttaccc aagagcaaat tgaggccctg gagaaagagt ttgagagaac ccattatcca     1260

gatgtgtttg cccgagaaag actagcagcc aaaatagatc tacctgaagc aagaatacag     1320

gtatggtttt ctaatcgaag ggccaaatgg agaagagaag aaaaactgag gaatcagaga     1380

agacaggcca gcaacacacc tagtcatatt cctatcagca gtagtttcag caccagtgtc     1440

taccaaccaa ttccacaacc caccacaccg gtttcctcct tcacatctgg ctccatgttg     1500

ggccgaacag acacagccct cacaaacacc tacagcgctc tgccgcctat gcccagcttc     1560

accatggcaa ataacctgcc tatgcaaccc ccagtcccca gccagacctc ctcatactcc     1620

tgcatgctgc ccaccagccc ttcggtgaat gggcggagtt atgataccta caccccccca     1680

catatgcaga cacacatgaa cagtcagcca atgggcacct cgggcaccac ttcaacagga     1740

ctcatttccc ctggtgtgtc agttccagtt caagttcccg gaagtgaacc tgatatgtct     1800

caatactggc caagattaca gtaaaaaaaa aaaaaaaaaa aaaaaggaaa ggaaatattg     1860

tgttaattca gtcagtgact atggggacac aacagttgag ctttcaggaa agaaagaaaa     1920

atggctgtta gagccgcttc agttctacaa ttgtgtcctg tattgtacca ctggggaagg     1980

aatggacttg aaacaaggac ctttgtatac agaaggcacg atatcagttg gaacaaatct     2040

tcattttggt atccaaactt ttattcattt tggtgtatta tttgtaaatg ggcatttgta     2100

tgttataatg aaaaaaagaa caatgtagac tggatggatg tttgatctgt gttggtcatg     2160

aagttgtttt tttttttttt aaaaagaaaa ccatgatcaa caagctttgc cacgaattta     2220

agagttttat caagatatat cgaatacttc tacccatctg ttcatagttt atggactgat     2280

gttccaagtt tgtatcattc ctttgcatat aattaaacct ggaacaacat gcactagatt     2340

tatgtcagaa atatctgttg gttttccaaa ggttgttaac agatgaagtt tatgtgcaaa     2400

aaagggtaag atataaattc aaggaagaaa aaaagttgat agctaaaagg tagagtgtgt     2460

cttcgatata atccaatttg ttttatgtca aaatgtaagt atttgtcttc cctagaaatc     2520

ctcagaatga tttctataat aaagttaatt tcatttatat ttgacaagaa tatagatgtt     2580

ttatacacat tttcatgcaa tcatacgttt cttttttggc cagcaaaagt taattgttct     2640

tagatatagt tgtattactg ttcacggtcc aatcattttg tgcatctaga gttcattcct     2700

aatcaattaa aagtgcttgc aagagtttta aacttaagtg ttttgaagtt gttcacaact     2760

acatatcaaa attaaccatt gttgattgta aaaaaccatg ccaaagcctt tgtatttcct     2820

ttattataca gttttctttt taaccttata gtgtggtgtt acaaatttta tttccatgtt     2880

agatcaacat tctaaaccaa tggttacttt cacacacact ctgttttaca tcctgatgat     2940

ccttaaaaaa taatccttat agataccata aatcaaaaac gtgttagaaa aaaattccac     3000

ttacagcagg gtgtagatct gtgcccattt atacccacaa catatataca aaatggtaac     3060

atttcccagt tagccattta attctaaagc tcaaagtcta gaaataattt aaaaatgcaa     3120

caagcgatta gctaggaatt gttttttgaa ttaggactgg cattttcaat ctgggcagat     3180

ttccattgtc agcctatttc aacaatgatt tcactgaagt atattcaaaa gtagatttct     3240

taaaggagac tttctgaaag ctgttgcctt tttcaaatag gccctctccc ttttctgtct     3300

ccctcccctt tgcacaagag gcatcatttc ccattgaacc actacagctg ttcccatttg     3360

aatcttgctt tctgtgcggt tgtggatggt tggagggtgg aggggggatg ttgcatgtca     3420

aggaataatg agcacagaca catcaacaga caacaacaaa gcagactgtg actggccggt     3480

gggaattaaa ggccttcagt cattggcagc ttaagccaaa cattcccaaa tctatgaagc     3540

agggcccatt gttggtcagt tgttatttgc aatgaagcac agttctgatc atgtttaaag     3600

tggaggcacg cagggcagga gtgcttgagc ccaagcaaag gatggaaaaa aataagcctt     3660

tgttgggtaa aaaaggactg tctgagactt tcatttgttc tgtgcaacat ataagtcaat     3720

acagataagt cttcctctgc aaacttcact aaaaagcctg ggggttctgg cagtctagat     3780

taaaatgctt gcacatgcag aaacctctgg ggacaaagac acacttccac tgaattatac     3840

tctgctttaa aaaaatcccc aaaagcaaat gatcagaaat gtagaaatta atggaaggat     3900

ttaaacatga ccttctcgtt caatatctac tgttttttag ttaaggaatt acttgtgaac     3960

agataattga gattcattgc tccggcatga aatatactaa taattttatt ccaccagagt     4020

tgctgcacat ttggagacac cttcctaagt tgcagttttt gtatgtgtgc atgtagtttt     4080

gttcagtgtc agcctgcact gcacagcagc acatttctgc aggggagtga gcacacatac     4140

gcactgttgg tacaattgcc ggtgcagaca tttctacctc ctgacatttt gcagcctaca     4200

ttccctgagg gctgtgtgct gagggaactg tcagagaagg gctatgtggg agtgcatgcc     4260

acagctgctg gctggcttac ttcttccttc tcgctggctg taatttccac cacggtcagg     4320

cagccagttc cggcccacgg ttctgttgtg tagacagcag agactttgga gacccggatg     4380

tcgcacgcca ggtgcaagag gtgggaatgg gagaaaagga gtgacgtggg agcggagggt     4440

ctgtatgtgt gcacttgggc acgtatatgt gtgctctgaa ggtcaggatt gccagggcaa     4500

agtagcacag tctggtatag tctgaagaag cggctgctca gctgcagaag ccctctggtc     4560

cggcaggatg ggaacggctg ccttgccttc tgcccacacc ctagggacat gagctgtcct     4620

tccaaacaga gctccaggca ctctcttggg gacagcatgg caggctctgt gtggtagcag     4680

tgcctgggag ttggcctttt actcattgtt gaaataattt ttgtttatta tttatttaac     4740

gatacatata tttatatatt tatcaatggg gtatctgcag ggatgttttg acaccatctt     4800

ccaggatgga gattatttgt gaagacttca gtagaatccc aggactaaac gtctaaattt     4860

tttctccaaa cttgactgac ttgggaaaac caggtgaata gaataagagc tgaatgtttt     4920

aagtaataaa cgttcaaact gctctaagta aaaaaatgca ttttactgca atgaatttct     4980

agaatatttt tcccccaaag ctatgcctcc taacccttaa atggtgaaca actggtttct     5040

tgctacagct cactgccatt tcttcttact atcatcacta ggtttcctaa gattcactca     5100

tacagtatta tttgaagatt cagctttgtt ctgtgaatgt catcttagga ttgtgtctat     5160

attcttttgc ttatttcttt ttactctggg cctctcatac tagtaagatt ttaaaaagcc     5220

ttttcttctc tgtatgtttg gctcaccaag gcgaaatata tattcttctc tttttcattt     5280

ctcaagaata aacctcatct gcttttttgt ttttctgtgt tttggcttgg tactgaatga     5340

ctcaactgct cggttttaaa gttcaaagtg taagtactta gggttagtac tgcttatttc     5400

aataatgttg acggtgacta tctttggaaa gcagtaacat gctgtcttag aaatgacatt     5460

aataatgggc ttaaacaaat gaataggggg gtccccccac tctccttttg tatgcctatg     5520

tgtgtctgat ttgttaaaag atggacaggg aattgattgc agagtgtcgc ttccttctaa     5580

agtagtttta ttttgtctac tgttagtatt taaagatcct ggaggtggac ataaggaata     5640

aatggaagag aaaagtagat attgtatggt ggctactaaa aggaaattca aaaagtctta     5700

gaacccgagc acctgagcaa actgcagtag tcaaaatatt tatctcatgt taaagaaagg     5760

caaatctagt gtaagaaatg agtaccatat agggttttga agttcatata ctagaaacac     5820

ttaaaagata tcatttcaga tattacgttt ggcattgttc ttaagtattt atatctttga     5880

gtcaagctga taattaaaaa aaatctgtta atggagtgta tatttcataa tgtatcaaaa     5940

tggtgtctat acctaaggta gcattattga agagagatat gtttatgtag taagttatta     6000

acataatgag taacaaataa tgtttccaga agaaaggaaa acacattttc agagtgcgtt     6060

tttatcagag gaagacaaaa atacacaccc ctctccagta gcttattttt acaaagccgg     6120

cccagtgaat tagaaaaaca aagcacttgg atatgatttt tggaaagccc aggtacactt     6180

attattcaaa atgcactttt actgagtttg aaaagtttct tttatattta aaataagggt     6240

tcaaatatgc atattcaatt tttatagtag ttatctattt gcaaagcata tattaactag     6300

taattggctg ttaattttat agacatggta gccagggaag tatatcaatg acctattaag     6360

tattttgaca agcaatttac atatctgatg acctcgtatc tctttttcag caagtcaaat     6420

gctatgtaat tgttccattg tgtgttgtat aaaatgaatc aacacggtaa gaaaaaggtt     6480

agagttatta aaataataaa ctgactaaaa tactcatttg aatttattca gaatgttcat     6540

aatgctttca aaggacatag cagagctttt gtggagtatc cgcacaacat tatttattat     6600

ctatggacta aatcaatttt ttgaagttgc tttaaaattt aaaagcacct ttgcttaata     6660

taaagccctt taattttaac tgacagatca attctgaaac tttattttga aaagaaaatg     6720

gggaagaatc tgtgtcttta gaattaaaag aaatgaaaaa aataaacccg acattctaaa     6780

aaaatagaat aagaaacctg atttttagta ctaatgaaat agcgggtgac aaaatagttg     6840

tctttttgat tttgatcaca aaaaataaac tggtagtgac aggatatgat ggagagattt     6900

gacatcctgg caaatcactg tcattgattc aattattcta attctgaata aaagctgtat     6960

acagtaaaa                                                             6969


<210>  2532
<211>  2660
<212>  DNA
<213>  homo sapiens

<400>  2532
agtttctcct ttgttttacg tttgggagga ggtggcattg gaaatagcag agtgcttcgc       60

ggtaacaggg gttggagtgc aatggtgtga tctcagctca ctgcaacccc tgcctcccag      120

gctccagcga tcctcccacc tcagcctcct gaatagctga ccaccagcac actaggcaaa      180

cccaccccac tcacggcctc ccttgggaat tcagacctaa ccatcgctga gctgaaacaa      240

atgtactgag gctggagcct gtgtgaacag aacagaagag gccttcactc tagtagtgct      300

cacagtccag caggtgtttg ctgaagacag cttactcaga tcactactgc ctggaggtgg      360

ttgatatatc ctggtgtaaa ccttcaagaa gggcacaggc aggaaaacat gagccagcaa      420

ctgaagaaac gggcaaagac aagacaccag aaaggcctgg gtggaagagc ccccagtggg      480

gctaagccca ggcaaggcaa gtcaagccaa gacctgcagg cggaaataga acctgtcagc      540

gcggtgtggg ccttatgtga tggctatgtg tgctatgagc ctggccctca ggctctcgga      600

ggggatgatt tctcagactg ttacatagaa tgcgtcataa ggggtgagtt ttctcaaccc      660

atcctggaag aggactcact ttttgagtcc ttggaatacc taaagaaagg atcagaacaa      720

cagctttctc aaaaggtttt cgaagcaagc tcccttgaat gttctttgga atacatgaaa      780

aaaggggtaa agaaagagct tccacaaaag atagttggag agaattcgct tgagtattct      840

gagtacatga caggcaagaa gcttccgcct ggaggaatac ctggcattga cctatcagat      900

cctaaacagc tcgcagaatt tgctagaaag aagcccccca taaataaaga atatgacagt      960

ctgagcgcaa tcgcttgtcc tcagagtgga tgcactagga agttgaggaa tagagctgcc     1020

ctgagaaagc atctcctcat tcatggtccc cgagaccacg tctgtgcgga atgtgggaaa     1080

gcgttcgttg agagctcaaa actaaagaga catttcctgg ttcatactgg agagaagccg     1140

tttcggtgca cttttgaagg gtgcggaaag cgcttctctc tggactttaa tttgcgtacg     1200

cacgtgcgca tccacacggg ggagaaacgt ttcgtgtgtc cctttcaagg ctgcaacagg     1260

aggtttattc agtcaaataa cctgaaagcc cacatcctaa cgcatgcaaa tacgaacaag     1320

aatgaacaag agggaaagta gtcctccaac aggatgaagc agattaacag aagagtgatc     1380

agtgacaaac atgcctcatt gattattgtt tctaggaagg aatttctaaa tcaatattgc     1440

aaccccaaaa gcggttataa tttggtgtta ctaagatgct cctacacttt gtgataccgt     1500

tttaaggaca tggtgcattt ttttttcttt tatttgtttt atttagaact ttttttattt     1560

gttttattta gaactttgtg tgttcttaaa gtgtgcttcc aacaggaagg tcagtgataa     1620

attttcaaaa gcataacctt caatatatta tctgttggat tattggatat aagacttatt     1680

ttcatgtact ataaatatga aaataacttt gatttttaat tgtgtagttt ccatttctta     1740

gcttttgcct tttaaattta tacttcagcc aggcatagtg actgatgcct gtaatcccaa     1800

cactttgttg ggaggccaaa gcaggaggat agcttgaggc caggagttcc agaccagcct     1860

gggcaacata gtgagatcct gtctctacaa aaaaatttgt ttttatttgt atttatatat     1920

ttttattttt gtttttgttg gtaggcgtct cgctctgtca cccaggctgg agtctagtgt     1980

cgtgatcttg gctcactgca acctccacct cccgggttca agtgattctc tggcctcagc     2040

ctcccaagta gctgggacta caggtgtgtg tcaccacgcc cggctaattt ttgtattttt     2100

agtagagatg gggtttcacc atgttggcca ggctagtctc aaactcctga cctccagtga     2160

tctgcccacc tcggcctccc aaagtgctgg gattacaggt gtgagccact gtgcctggcc     2220

ccccacaaca tgtttaaact tagctaggcc tggttgcata cgcctgtgtt cccagctact     2280

caggaggctg aagcaggagg atagcttgag cccaggagtt tgaggctaca gtgagctgtg     2340

attgcaccac tgtactccag actggataac agcaagagcc catcttttaa aaaaagtaaa     2400

aattaaaaat atacttcatg gttcatgtca tagccctaga gaatgaaaaa tttgcagtag     2460

atagtcaata aatgaatcag tagttaaata ttccttaaag tcaactgtat ttcattgtga     2520

tttttgtttt ctttttatca ttgtatcaaa ctatatggaa atcatatggt tagatgtgat     2580

tatttgataa tgttagtcca tttgaatcca ttttagatat ttcacaatta aagaatatga     2640

aacttcagaa aaaaaaaaaa                                                 2660


<210>  2533
<211>  6960
<212>  DNA
<213>  homo sapiens

<400>  2533
acacagtact ctcagcttgt tggtggaagc ccctcatctg ccttcattct gaaggcaggg       60

cccggcagag gaaggatcag agggtcgcgg ccggagggtc ccggccggtg gggccaactc      120

agagggagag gaaagggcta gagacacgaa gaacgcaaac catcaaattt agaagaaaaa      180

gccctttgac tttttccccc tctccctccc caatggctgt gtagcaaaca tccctggcga      240

taccttggaa aggacgaagt tggtctgcag tcgcaatttc gtgggttgag ttcacagttg      300

tgagtgcggg gctcggagat ggagccgtgg tcctctaggt ggaaaacgaa acggtggctc      360

tgggatttca ccgtaacaac cctcgcattg accttcctct tccaagctag agaggtcaga      420

ggagctgctc cagttgatgt actaaaagca ctagattttc acaattctcc agagggaata      480

tcaaaaacaa cgggattttg cacaaacaga aagaattcta aaggctcaga tactgcttac      540

agagtttcaa agcaagcaca actcagtgcc ccaacaaaac agttatttcc aggtggaact      600

ttcccagaag acttttcaat actatttaca gtaaaaccaa aaaaaggaat tcagtctttc      660

cttttatcta tatataatga gcatggtatt cagcaaattg gtgttgaggt tgggagatca      720

cctgtttttc tgtttgaaga ccacactgga aaacctgccc cagaagacta tcccctcttc      780

agaactgtta acatcgctga cgggaagtgg catcgggtag caatcagcgt ggagaagaaa      840

actgtgacaa tgattgttga ttgtaagaag aaaaccacga aaccacttga tagaagtgag      900

agagcaattg ttgataccaa tggaatcacg gtttttggaa caaggatttt ggatgaagaa      960

gtttttgagg gggacattca gcagtttttg atcacaggtg atcccaaggc agcatatgac     1020

tactgtgagc attatagtcc agactgtgac tcttcagcac ccaaggctgc tcaagctcag     1080

gaacctcaga tagatgagta tgcaccagag gatataatcg aatatgacta tgagtatggg     1140

gaagcagagt ataaagaggc tgaaagtgta acagagggac ccactgtaac tgaggagaca     1200

atagcacaga cggagataaa tggccatggt gcatatggag agaaaggaca gaaaggagaa     1260

ccagcagtgg ttgagcctgg tatgcttgtc gaaggaccac caggaccagc aggacctgca     1320

ggtattatgg gtcctccagg tctacaaggc cccactggac cccctggtga ccctggcgat     1380

aggggccccc caggacgtcc tggcttacca ggggctgatg gtctacctgg tcctcctggt     1440

actatgttga tgttaccgtt ccgttatggt ggtgatggtt ccaaaggacc aaccatctct     1500

gctcaggaag ctcaggctca agctattctt cagcaggctc ggattgctct gagaggccca     1560

cctggcccaa tgggtctaac tggaagacca ggtcctgtgg gggggcctgg ttcatctggg     1620

gccaaaggtg agagtggtga tccaggtcct cagggccctc gaggcgtcca gggtccccct     1680

ggtccaacgg gaaaacctgg aaaaaggggt cgtccaggtg cagatggagg aagaggaatg     1740

ccaggagaac ctggggcaaa gggagatcga gggtttgatg gacttccggg tctgccaggt     1800

gacaaaggtc acaggggtga acgaggtcct caaggtcctc caggtcctcc tggtgatgat     1860

ggaatgaggg gagaagatgg agaaattgga ccaagaggtc ttccaggtga agctggccca     1920

cgaggtttgc tgggtccaag gggaactcca ggagctccag ggcagcctgg tatggcaggt     1980

gtagatggcc ccccaggacc aaaagggaac atgggtcccc aaggggagcc tgggcctcca     2040

ggtcaacaag ggaatccagg acctcagggt cttcctggtc cacaaggtcc aattggtcct     2100

cctggtgaaa aaggaccaca aggaaaacca ggacttgctg gacttcctgg tgctgatggg     2160

cctcctggtc atcctgggaa agaaggccag tctggagaaa agggggctct gggtccccct     2220

ggtccacaag gtcctattgg atacccgggc ccccggggag taaagggagc agatggtgtc     2280

agaggtctca agggatctaa aggtgaaaag ggtgaagatg gttttccagg attcaaaggt     2340

gacatgggtc taaaaggtga cagaggagaa gttggtcaaa ttggcccaag aggggaagat     2400

ggccctgaag gacccaaagg tcgagcaggc ccaactggag acccaggtcc ttcaggtcaa     2460

gcaggagaaa agggaaaact tggagttcca ggattaccag gatatccagg aagacaaggt     2520

ccaaagggtt ccactggatt ccctgggttt ccaggtgcca atggagagaa aggtgcacgg     2580

ggagtagctg gcaaaccagg ccctcggggt cagcgtggtc caacgggtcc tcgaggttca     2640

agaggtgcaa gaggtcccac tgggaaacct gggccaaagg gcacttcagg tggcgatggc     2700

cctcctggcc ctccaggtga aagaggtcct caaggacctc agggtccagt tggattccct     2760

ggaccaaaag gccctcctgg accacctggg aaggatgggc tgccaggaca ccctgggcaa     2820

cgtggggaga ctggatttca aggcaagacc ggccctcctg ggccaggggg agtggttgga     2880

ccacagggac caaccggtga gactggtcca ataggggaac gtgggcatcc tggccctcct     2940

ggccctcctg gtgagcaagg tcttcctggt gctgcaggaa aagaaggtgc aaagggtgat     3000

ccaggtcctc aaggtatctc agggaaagat ggaccagcag gattacgtgg tttcccaggg     3060

gaaagaggtc ttcctggagc tcagggtgca cctggactga aaggagggga aggtccccag     3120

ggcccaccag gtccagttgg ctcaccagga gaacgtgggt cagcaggtac agctggccca     3180

attggtttac cagggcgccc gggacctcag ggtcctcctg gtccagctgg agagaaaggt     3240

gctcctggag aaaaaggtcc ccaagggcct gcagggagag atggagttca aggtcctgtt     3300

ggtctcccag ggccagctgg tcctgccggc tcccctgggg aagacggaga caagggtgaa     3360

attggtgagc cgggacaaaa aggcagcaag ggtgacaagg gagaaaatgg ccctcccggt     3420

cccccaggtc ttcaaggacc agttggtgcc cctggaattg ctggaggtga tggtgaacca     3480

ggtcctagag gacagcaggg gatgtttggg caaaaaggtg atgagggtgc cagaggcttc     3540

cctggacctc ctggtccaat aggtcttcag ggtctgccag gcccacctgg tgaaaaaggt     3600

gaaaatgggg atgttggtcc catggggcca cctggtcctc caggcccaag aggccctcaa     3660

ggtcccaatg gagctgatgg accacaagga cccccagggt ctgttggttc agttggtggt     3720

gttggagaaa agggtgaacc tggagaagca gggaacccag ggcctcctgg ggaagcaggt     3780

gtaggcggtc ccaaaggaga aagaggagag aaaggggaag ctggtccacc tggagctgct     3840

ggacctccag gtgccaaggg gccaccaggt gatgatggcc ctaagggtaa cccgggtcct     3900

gttggttttc ctggagatcc tggtcctcct ggggaacctg gccctgcagg tcaagatggt     3960

gttggtggtg acaagggtga agatggagat cctggtcaac cgggtcctcc tggcccatct     4020

ggtgaggctg gcccaccagg tcctcctgga aaacgaggtc ctcctggagc tgcaggtgca     4080

gagggaagac aaggtgaaaa aggtgctaag ggggaagcag gtgcagaagg tcctcctgga     4140

aaaaccggcc cagtcggtcc tcagggacct gcaggaaagc ctggtccaga aggtcttcgg     4200

ggcatccctg gtcctgtggg agaacaaggt ctccctggag ctgcaggcca agatggacca     4260

cctggtccta tgggacctcc tggcttacct ggtctcaaag gtgaccctgg ctccaagggt     4320

gaaaagggac atcctggttt aattggcctg attggtcctc caggagaaca aggggaaaaa     4380

ggtgaccgag ggctccctgg aactcaagga tctccaggag caaaagggga tgggggaatt     4440

cctggtcctg ctggtccctt aggtccacct ggtcctccag gtttaccagg tcctcaaggc     4500

ccaaagggta acaaaggctc tactggaccc gctggccaga aaggtgacag tggtcttcca     4560

gggcctcctg ggtctccagg tccacctggt gaagtcattc agcctttacc aatcttgtcc     4620

tccaaaaaaa cgagaagaca tactgaaggc atgcaagcag atgcagatga taatattctt     4680

gattactcgg atggaatgga agaaatattt ggttccctca attccctgaa acaagacatt     4740

gagcatatga aatttccaat gggtactcag accaatccag cccgaacttg taaagacctg     4800

caactcagcc atcctgactt cccagatggt gaatattgga ttgatcctaa ccaaggttgc     4860

tcaggagatt ccttcaaagt ttactgtaat ttcacatctg gtggtgagac ttgcatttat     4920

ccagacaaaa aatctgaggg agtaagaatt tcatcatggc caaaggagaa accaggaagt     4980

tggtttagtg aatttaagag gggaaaactg ctttcatact tagatgttga aggaaattcc     5040

atcaatatgg tgcaaatgac attcctgaaa cttctgactg cctctgctcg gcaaaatttc     5100

acctaccact gtcatcagtc agcagcctgg tatgatgtgt catcaggaag ttatgacaaa     5160

gcacttcgct tcctgggatc aaatgatgag gagatgtcct atgacaataa tccttttatc     5220

aaaacactgt atgatggttg tgcgtccaga aaaggctatg aaaagactgt cattgaaatc     5280

aatacaccaa aaattgatca agtacctatt gttgatgtca tgatcaatga ctttggtgat     5340

cagaatcaga agttcggatt tgaagttggt cctgtttgtt ttcttggcta agattaagac     5400

aaagaacata tcaaatcaac agaaaatata ccttggtgcc accaacccat tttgtgccac     5460

atgcaagttt tgaataagga tggtatagaa aacaacgctg catatacagg taccatttag     5520

gaaataccga tgcctttgtg ggggcagaat cacatggcaa aagctttgaa aatcataaag     5580

atataagttg gtgtggctaa gatggaaaca gggctgattc ttgattccca attctcaact     5640

ctccttttcc tatttgaatt tctttggtgc tgtagaaaac aaaaaaagaa aaatatatat     5700

tcataaaaaa tatggtgctc attctcatcc atccaggatg tactaaaaca gtgtgtttaa     5760

taaattgtaa ttattttgtg tacagttcta tactgttatc tgtgtccatt tccaaaactt     5820

gcacgtgtcc ctgaattcca tctgactcta attttatgag aattgcagaa ctctgatggc     5880

aataaatata tgtattatga aaaaataaag ttgtaatttc tgatgactct aagtcccttt     5940

ctttggttaa taataaaatg cctttgtata tattgatgtt gaagagttca attatttgat     6000

gtcgccaaca aaattctcag agggcaaaaa tctggaagac ttttggaagc acactctgat     6060

caactcttct ctgccgacag tcattttgct gaatttcagc caaaaatatt atgcattttg     6120

atgctttatt caaggctata cctcaaactt tttcttctca gaatccagga tttcacagga     6180

tacttgtata tatggaaaac aagcaagttt atatttttgg acagggaaat gtgtgtaaga     6240

aagtatatta acaaatcaat gcctccgtca agcaaacaat catatgtata ctttttttct     6300

acgttatctc atctccttgt tttcagtgtg cttcaataat gcaggttaat attaaagatg     6360

gaaattaagc aattatttat gaatttgtgc aatgttagat tttcttatca atcaagttct     6420

tgaatttgat tctaagttgc atattataac agtctcgaaa attattttac ttgcccaaca     6480

aatattactt ttttcctttc aagataattt tataaatcat ttgacctacc taattgctaa     6540

atgaataaca tatggtggac tgttattaag agtatttgtt ttaagtcatt caggaaaatc     6600

taaacttttt tttccactaa ggtatttact ttaaggtagc ttgaaatagc aatacaattt     6660

aaaaattaaa aactgaattt tgtatctatt ttaagtaata tatgtaagac ttgaaaataa     6720

atgttttatt tcttatataa agtgttaaat taattgatac cagatttcac tggaacagtt     6780

tcaactgata atttatgaca aaagaacata cctgtaatat tgaaattaaa aagtgaaatt     6840

tgtcataaag aatttctttt atttttgaaa tcgagtttgt aaatgtcctt ttaagaaggg     6900

agatatgaat ccaataaata aactcaagtc ttggctacct ggaaaaaaaa aaaaaaaaaa     6960


<210>  2534
<211>  5910
<212>  DNA
<213>  homo sapiens

<400>  2534
agctccagcc gcactgcccc gatggctccc tacccctgtg gctgccacat cctgctgctg       60

ctcttctgct gcctggcggc tgcccgggcc aacctgctga acctgaactg gctttggttc      120

aataatgagg acaccagcca tgcagctacc acgatccctg agccccaggg gcccctgcct      180

gtgcagccca cagcagatac caccacacac gtgacccccc ggaatggttc cacagagcca      240

gcgacagccc ctggcagccc tgagccaccc tcagagctgc tggaagatgg ccaggacacc      300

cccacttctg ccgagagccc ggacgcgcca gaggagaaca ttgccggtgt cggagccgag      360

atcctgaacg tggccaaagg catccggagc ttcgtccagc tgtggaatga cactgtcccc      420

actgagagct tggccagggc ggaaaccctg gtcctggaga ctcctgtggg cccccttgcc      480

ctcgctgggc cttccagcac cccccaggag aatgggacca ctctctggcc cagccgtggc      540

attcctagct ctccgggcgc ccacacaacc gaggctggca ccttgcctgc acccacccca      600

tcgcctccct ccctgggcag gccctgggca ccactcacgg ggccctcagt gccaccacca      660

tcttcagagc gcatcagcga ggaggtgggg ctgctgcagc tccttgggga ccccccgccc      720

cagcaggtca cccagacgga tgaccccgac gtcgggctgg cctacgtctt tgggccagat      780

gccaacagtg gccaagtggc ccggtaccac ttccccagcc tcttcttccg tgacttctca      840

ctgctgttcc acatccggcc agccacagag ggcccagggg tgctgttcgc catcacggac      900

tcggcgcagg ccatggtctt gctgggcgtg aagctctctg gggtgcagga cgggcaccag      960

gacatctccc tgctctacac agaaccaggt gcaggccaga cccacacagc cgccagcttc     1020

cggctccccg ccttcgtcgg ccagtggaca cacttagccc tcagtgtggc aggtggcttt     1080

gtggccctct acgtggactg tgaggagttc cagagaatgc cgcttgctcg gtcctcacgg     1140

ggcctggagc tggagcctgg cgccgggctc ttcgtggctc aggcgggggg agcggaccct     1200

gacaagttcc agggggtgat cgctgagctg aaggtgcgca gggaccccca ggtgagcccc     1260

atgcactgcc tggacgagga aggcgatgac tcagatgggg catccggaga ctctggcagc     1320

gggctcgggg acgcccggga gcttctcagg gaggagacgg gcgcggccct aaaacccagg     1380

ctccccgcgc caccccccgt caccacgcca cccttggctg gaggcagcag cacggaagat     1440

tccagaagtg aagaagtcga ggagcagacc acggtggctt cgttaggagc tcagacactt     1500

cctggctcag attctgtctc cacgtgggac gggagtgtcc ggacccctgg gggccgcgtg     1560

aaagagggcg gcctgaaggg gcagaaaggg gagccaggtg ttccgggccc acctggccgg     1620

gcaggccccc caggatcccc atgcctacct ggtcccccgg gtctcccgtg cccagtgagt     1680

cccctgggtc ctgcaggccc agcgttgcaa actgtccccg gaccacaagg acccccaggg     1740

cctccgggga gggacggcac ccctggaagg gacggcgagc cgggcgaccc cggtgaagac     1800

ggaaagccgg gcgacaccgg gccacaaggc ttccccggga ctccagggga cgtaggtccc     1860

aagggcgaca agggagaccc tggggttgga gagagagggc ccccaggacc ccaagggcct     1920

ccagggcccc caggaccctc cttcagacac gacaagctga ccttcattga catggaggga     1980

tctggcttcg ggggcgatct ggaggccctg cggggtcctc gaggcttccc tggacctccc     2040

ggaccccccg gtgtcccagg cctgcccggc gagccaggcc gctttggggt gaacagctcc     2100

gacgtcccag gacccgccgg ccttcctggt gtgcctgggc gcgagggtcc ccccgggttt     2160

cctggcctcc cgggaccccc aggccctccg ggaagagagg ggcccccagg aaggactggg     2220

cagaaaggca gcctgggtga agcaggcgcc ccaggacata aggggagcaa gggagccccc     2280

ggtcctgctg gtgctcgtgg ggagagcggc ctggcaggag cccccggacc tgctggacca     2340

ccaggccccc ctgggccccc tgggccccca ggaccaggac tccccgctgg atttgatgac     2400

atggaaggct ccggggggcc cttctggtca acagcccgaa gcgctgatgg gccacaggga     2460

cctcccggcc tgccgggact taagggggat cctggcgtgc ctgggctgcc gggggcgaag     2520

ggagaagttg gagcagatgg agtccccggg ttccccggcc tccctggcag agagggcatt     2580

gctgggcccc aggggccaaa gggagacaga ggcagccggg gagaaaaggg agatccaggg     2640

aaggacggag tcgggcagcc gggcctccct ggcccccccg gacccccggg acctgtggtc     2700

tacgtgtcgg agcaggacgg atccgtcctg agcgtgccgg gacctgaggg ccggccgggt     2760

ttcgcaggct ttcccggacc tgcaggaccc aagggcaacc tgggctctaa gggcgaacga     2820

ggctccccgg gacccaaggg tgagaagggt gaaccgggca gcatcttcag ccccgacggc     2880

ggtgccctgg gccctgccca gaaaggagcc aagggagagc cgggcttccg aggacccccg     2940

ggtccatacg gacggccggg gtacaaggga gagattggct ttcctggacg gccgggtcgc     3000

cccgggatga acggattgaa aggagagaaa ggggagccgg gagatgccag ccttggattt     3060

ggcatgaggg gaatgcccgg ccccccagga cctccagggc ccccaggccc tccagggact     3120

cctgtttacg acagcaatgt gtttgctgag tccagccgcc ccgggcctcc aggattgcca     3180

gggaatcagg gccctccagg acccaagggc gccaaaggag aagtgggccc ccccggacca     3240

ccagggcagt ttccgtttga ctttcttcag ttggaggctg aaatgaaggg ggagaaggga     3300

gaccgaggtg atgcaggaca gaaaggcgaa aggggggagc ccgggggcgg cggtttcttc     3360

ggctccagcc tgcccggccc ccccggcccc ccaggcccac gtggctaccc tgggattcca     3420

ggtcccaagg gagagagcat ccggggccag cccggcccac ctggacctca gggacccccc     3480

ggcatcggct acgaggggcg ccagggccct cccggccccc caggcccccc agggccccct     3540

tcatttcctg gccctcacag gcagactatc agcgttcccg gccctccggg cccccctggg     3600

ccccctgggc cccctggaac catgggcgcc tcctcagggg tgaggctctg ggctacacgc     3660

caggccatgc tgggccaggt gcacgaggtt cccgagggct ggctcatctt cgtggccgag     3720

caggaggagc tctacgtccg cgtgcagaac gggttccgga aggtccagct ggaggcccgg     3780

acaccactcc cacgagggac ggacaatgaa gtggccgcct tgcagccccc cgtggtgcag     3840

ctgcacgaca gcaaccccta cccgcggcgg gagcaccccc accccaccgc gcggccctgg     3900

cgggcagatg acatcctggc cagcccccct cgcctgcccg agccccagcc ctaccccgga     3960

gccccgcacc acagctccta cgtgcacctg cggccggcgc gacccacaag cccacccgcc     4020

cacagccacc gcgacttcca gccggtgctc cacctggttg cgctcaacag ccccctgtca     4080

ggcggcatgc ggggcatccg cggggccgac ttccagtgct tccagcaggc gcgggccgtg     4140

gggctggcgg gcaccttccg cgccttcctg tcctcgcgcc tgcaggacct gtacagcatc     4200

gtgcgccgtg ccgaccgcgc agccgtgccc atcgtcaacc tcaaggacga gctgctgttt     4260

cccagctggg aggctctgtt ctcaggctct gagggtccgc tgaagcccgg ggcacgcatc     4320

ttctcctttg acggcaagga cgtcctgagg caccccacct ggccccagaa gagcgtgtgg     4380

catggctcgg accccaacgg gcgcaggctg accgagagct actgtgagac gtggcggacg     4440

gaggctccct cggccacggg ccaggcctcc tcgctgctgg ggggcaggct cctggggcag     4500

agtgccgcga gctgccatca cgcctacatc gtgctctgca ttgagaacag cttcatgact     4560

gcctccaagt agccaccgcc tggatgcgga tggccggaga ggaccggcgg ctcggaggaa     4620

gcccccaccg tgggcaggga gcggccggcc agcccctggc cccaggacct ggctgccata     4680

ctttcctgta tagttcacgt ttcatgtaat cctcaagaaa taaaaggaag ccaaagagtg     4740

tattttttta aaagtttaaa acagaagcct gatgctgaca ttcacctgcc ccaactctcc     4800

cctgacctgt gagcccagct gggtcaggca gggtgcagta tcatgccctg tgcaacctct     4860

tggcctgatc agaccacggc tcgatttctc caggatttcc tgctttggga agccgtgctc     4920

gccccagcag gtgctgactt catctcccac ctagcagcac cgttctgtgc acaaaaccca     4980

gacctgttag cagacaggcc ccgtgaggca atgggagctg aggccacact cagcacaagg     5040

ccatctgggc tcctccaggg tgtgtgctcg ccctgcggta gatgggaggg aggctcaggt     5100

ccctggggct agggggagcc ccttctgctc agctctgggc cattctccac agcaacccca     5160

ggctgaagca ggttcccaag ctcagaggcg cactgtgacc cccagctccg gcctgtcctc     5220

caacaccaag cacagcagcc tggggctggc ctcccaaatg agccatgaga tgatacatcc     5280

aaagcagaca gctccaccct ggccgagtcc aagctgggag attcaaggga cccatgagtt     5340

ggggtctggc agcctcccat ccagggcccc catctcatgc ccctggctgg gacgtggctc     5400

agccagcact tgtccagctg agcgccagga tggaacacgg ccacatcaaa gaggctgagg     5460

ctggcacagg acatgcggta gccagcacac agggcagtga gggagggctg tcatctgtgc     5520

actgcccatg gacaggctgg ctccagatgc agggcagtca ttggctgtct cctaggaaac     5580

ccatatcctt accctccttg ggactgaagg ggaaccccgg ggtgcccaca ggccgccctg     5640

cgggtgaaca aagcagccac gaggtgcaac aaggtcctct gtcagtcaca gccacccctg     5700

agatccggca acatcaaccc gagtcattcg ttctgtggag ggacaagtgg actcagggca     5760

gcgccaggct gaccacagca cagccaacac gcacctgcct caggactgcg acgaaaccgg     5820

tggggctggt tctgtaattg tgtgtgatgt gaagccaatt cagacaggca aataaaagtg     5880

accttttaca ctgaaaaaaa aaaaaaaaaa                                      5910


<210>  2535
<211>  8689
<212>  DNA
<213>  homo sapiens

<400>  2535
ctcctctctt ttggaaaccg gagaggtgga gggagggcaa caccgctgca aaggagaggc       60

ccgccaagtc tgcccgcctg caaagtgttg ctttgacaca ttcttattat ggaagttaag      120

taaaaatata gacatattaa aaaataactc cggacgtgga gctgctacgg agaaggaaac      180

cgggggaaag aaaaccagta ggcaggccaa tggtttttcg gcagcgcgct ggcaagtttg      240

tggaacactt tctaggaatt aggtcttttc ctcccccttc atcatcttga cttctgaagg      300

aagaacttgg ctttggattg cagtggagcc taaggagaga gggttagaca cactcgaata      360

atccctctgg ctgggctgaa tttgtgggaa tttaggaagc cagagtgctg gaaatacagc      420

agcctttgaa gtaccctctg ttaatttgga tggatctcag tgtgccccgt tcgagacctc      480

tccaccaacc ccttctgatc ttgcgatttg ctcttcttga ctttaattag tatctaggaa      540

agtctaaact ttggacctac ctcttttttt gatactcatt tttgtacttt tgctctctgg      600

gattggtttc ttaaagaatc tggatccttt ttaatatgtc aaaatgagtc tgctgatgtt      660

tacacaacta ctgctctgtg gatttttata tgttcgggtt gatggatcgc gtcttcgcca      720

ggaggacttt cccccgcgga ttgtggagca tccttccgat gtcatcgtct ctaagggcga      780

gcccacgact ctgaactgca aggcggaggg ccggccaacg cccaccattg agtggtacaa      840

agatggggag cgagtggaga ctgacaagga cgatccccgg tcccacagga tgcttctgcc      900

cagcggatcc ttattcttct tgcgcatcgt gcacgggcgc aggagtaaac ctgatgaagg      960

aagctacgtt tgtgttgcga ggaactatct tggtgaagca gtgagtcgaa atgcgtctct     1020

ggaagtggca ttgttacgag atgacttccg acaaaacccc acagatgttg tagtggcagc     1080

tggagagcct gcaatcctgg agtgccagcc tccccgggga cacccagaac ccaccatcta     1140

ctggaaaaaa gacaaagttc gaattgatga caaggaagaa agaataagta tccgtggtgg     1200

aaaactgatg atctccaata ccaggaaaag tgatgcaggg atgtatactt gtgttggtac     1260

caatatggtg ggagaaaggg acagtgaccc agcagagctg actgtctttg aacgacccac     1320

atttctcagg aggccaatta accaggtggt actggaggaa gaagctgtag aatttcgttg     1380

tcaagtccaa ggagatcctc aaccaactgt gaggtggaaa aaggatgatg cagacttgcc     1440

aagaggaagg tatgacatca aagacgatta cacactaaga attaaaaaga ccatgagtac     1500

agatgaaggc acctatatgt gtattgctga gaatcgggtt ggaaaaatgg aagcctctgc     1560

tacactcacc gtccgagctc ccccacagtt tgtggttcgg ccaagagatc agattgttgc     1620

tcaaggtcga acagtgacat ttccctgtga aactaaagga aacccacagc cagctgtttt     1680

ttggcagaaa gaaggcagcc agaacctact tttcccaaac caaccccagc agcccaacag     1740

tagatgctca gtgtcaccaa ctggagacct cacaatcacc aacattcaac gttccgacgc     1800

gggttactac atctgccagg ctttaactgt ggcaggaagc attttagcaa aagctcaact     1860

ggaggttact gatgttttga cagatagacc tccacctata attctacaag gcccagccaa     1920

ccaaacgctg gcagtggatg gtacagcgtt actgaaatgt aaagccactg gtgatcctct     1980

tcctgtaatt agctggttaa aggagggatt tacttttccg ggtagagatc caagagcaac     2040

aattcaagag caaggcacac tgcagattaa gaatttacgg atttctgata ctggcactta     2100

tacttgtgtg gctacaagtt caagtggaga gacttcctgg agtgcagtgc tggatgtgac     2160

agagtctgga gcaacaatca gtaaaaacta tgatttaagt gacctgccag ggccaccatc     2220

caaaccgcag gtcactgatg ttactaagaa cagtgtcacc ttgtcctggc agccaggtac     2280

ccctggaacc cttccagcaa gtgcatatat cattgaggct ttcagccaat cagtgagcaa     2340

cagctggcag accgtggcaa accatgtaaa gaccaccctc tatactgtaa gaggactgcg     2400

gcccaataca atctacttat tcatggtcag agcgatcaac ccccaaggtc tcagtgaccc     2460

aagtcccatg tcagatcctg tgcgcacaca agatatcagc ccaccagcac aaggagtgga     2520

ccacaggcaa gtgcagaaag agctaggaga tgtccttgtc cgtcttcata atccagttgt     2580

gctgactccc accacggttc aggtcacatg gacggttgat cgccaacccc agtttatcca     2640

aggctaccga gtgatgtatc gtcagacttc aggtctgcag gcgacatctt cgtggcagaa     2700

tttagatgcc aaagtcccga ctgaacgaag tgctgtctta gtcaacctga aaaagggggt     2760

gacttatgaa attaaagtac ggccatattt taatgagttc caaggaatgg atagtgaatc     2820

taaaacggtt cgtactactg aagaagcccc aagtgcccca ccacagtctg tcactgtact     2880

gacagttgga agctacaata gcacaagtat tagtgtttcc tgggatcctc ctcctccaga     2940

tcaccagaat ggaattatcc aagaatacaa gatctggtgt ctaggaaatg aaacgcgatt     3000

ccatatcaac aaaactgtgg atgcagccat tcggtccgta ataattggtg gattattccc     3060

aggtattcaa taccgggtag aggttgcagc tagtaccagt gcaggggttg gagtaaagag     3120

tgagccacag ccaataataa tcgggagacg caatgaagtt gtcattactg aaaacaataa     3180

cagcataact gagcaaatca ctgatgtggt gaagcaacca gcctttatag ctggtattgg     3240

tggtgcctgc tgggtaattc tgatgggttt tagcatatgg ttgtattggc gaagaaagaa     3300

gaggaaggga ctcagtaatt atgctgttac gtttcaaaga ggagatggag gactaatgag     3360

caatggaagc cgtccaggtc ttctcaatgc tggtgatccc agctatccat ggcttgctga     3420

ttcttggcca gccacgagct tgccagtaaa taatagcaac agtggcccaa atgagattgg     3480

aaattttggc cgtggagatg tgctgccacc agttccaggc caaggggata aaacagcaac     3540

gatgctctca gatggagcca tttatagtag cattgacttc actaccaaaa ccagttacaa     3600

cagttccagc caaataacac aggctacccc atatgccacg acacagatct tgcattccaa     3660

cagcatacat gaattggctg tcgatctgcc tgatccacaa tggaaaagct caattcagca     3720

aaaaacagat ctgatgggat ttggttattc tctacctgat cagaacaaag gtaacaatgg     3780

tgggaaaggt ggaaaaaaga agaaaaataa aaactcttct aaaccacaga aaaacaatgg     3840

atccacttgg gccaatgtcc ctctacctcc ccccccagtc cagccccttc ctggcacgga     3900

gctggaacac tatgcagtgg aacaacaaga aaatggctat gacagtgata gctggtgccc     3960

accattgcca gtacaaactt acttacacca aggtctggaa gatgaactgg aagaagatga     4020

tgatagggtc ccaacacctc ctgttcgagg cgtggcttct tctcctgcta tctcctttgg     4080

acagcagtcc actgcaactc ttactccatc cccacgggaa gagatgcaac ccatgctgca     4140

ggctcacctg gatgagttga caagagccta tcagtttgat atagcaaaac aaacatggca     4200

cattcaaagc aataatcaac ctccacagcc tccagttcca ccgttaggtt atgtgtctgg     4260

agccttgatt tctgatttgg aaacggatgt tgcagatgat gatgccgacg acgaagagga     4320

agctttagaa atccccaggc ccctgagagc actggaccag actcctggat ccagcatgga     4380

caatctagac agctctgtga caggaaaagc ctttacctcc tctcaaagac ctcgacctac     4440

cagcccattt tctactgaca gtaacaccag tgcagccctg agtcaaagtc agaggcctcg     4500

gcccactaaa aaacacaagg gagggcggat ggaccaacaa ccagcattgc ctcatcgaag     4560

ggaaggaatg acagatgagg aggccttggt gccctatagc aagcccagtt tcccatctcc     4620

aggtggccac agctcatcag gaacagcttc ttctaaggga tccactggac ctaggaaaac     4680

cgaggtgttg agagcaggcc accagcgcaa tgccagcgac cttcttgaca taggatatat     4740

gggctccaac agtcaaggac agtttacagg tgaattatag taaatgagag gagacataca     4800

aagctgctct gaaggaccat caggtccgga ctcatggaag tgatgactct aaacagtgca     4860

atgaacaatt tatttatgta ctattaaaag aactgtaaat gcaatgtaaa gacacacagc     4920

cacacatatc ccacagatat tttcattgtg ttcttctctt aagtacacca cccaccttaa     4980

ctctttcttg tcaggagtat ataaaaaaga aagaaaacaa aactcgccct acaggaagaa     5040

aaggattctc ctctgtatat aatttctttt gtgcattgct atgcaagctc actcttttta     5100

gctctgctca tattattgtc tgttcttatt ggtctgttgt actatatgtg aattaatagg     5160

ctgtggtgcc atatattaac ttttaattgt gtaactttta tgtttaaatt ttgcactgca     5220

attttatttg gtgataagca caaatctcta ctcctcatga catgaagaaa aagactgaat     5280

gtgaagggag tttctgtact gtaagctaga ttggataatg atggctgtaa caaatcatgt     5340

tagatggttt tcagttgggg tgtagaaata ggaagatgca aaggaacaat ggtgttggca     5400

aagtcttctt tgaatatcag ggactgagtc aataaaaaaa atagtagaaa ggtggctttt     5460

actattgaca aaagccgggg tcaaaaaaag tagtttaagt cttaagactg aatatgcatt     5520

aaagtatgca ggtagcaaag atgtaataaa tttgcttaaa aaaagaaatt aaagttttat     5580

ttagaatcaa ttttacctgt cattgtaatt gacccatctg agaattacaa taagcaagag     5640

gaaattaagg tgttttgcaa gagctgtatt tatattacag ttttttaaaa acattttctg     5700

aattatcgta attaagctct ccaactcgtt aagtcagaat ataatatgaa gttccccaag     5760

gaaacgaaca aaatgaactc tagaatatct agcaaatagt taaagaagca atttattatt     5820

agggcatact cgggctgttt ccaaatataa actctattgc aatatcttat ttcatctttc     5880

taatacatgt acagtgcaca ctagaggata gagctgcatc acttaaattc atgacttaaa     5940

aaataataca gtttatatac aacttgtttt ttatttgatt aagaagtgaa gtttacgcca     6000

cccaatgtat agccaaattg tacgtgctta aaaaacagtg ccgagagtat gttcagttcg     6060

cagtaagtag atttattgga ataaatattc tatggtacat tctcagaaat tggcttccaa     6120

ctaaaatacg tttgacccat tttgaataag gaaattgaaa agaaaaattt aaaaggagaa     6180

aaaaatgcat gtttataaac tttttaaata aaaccagacc ttgtaagtgg acattaataa     6240

ttgtcctgcc tcatttgttt tcacgacttt gacaacaaga agttcctgaa cattagtcat     6300

gtatgctcag aataaatgtg actttgaaat atatgttagc tactgtacat gtatagtcag     6360

tcaagtagaa gaggaccttc ctgaaattcc cacttgtgac attttcccat gggtttccta     6420

cacaatctta aattttattt ctgtctatac tttctcaaat ttttcctatg ataagttcag     6480

ttgttggtac tcttctaaaa atattcaacg tgattaggat cagttctaaa atacgggacc     6540

cctttgagtg acaattcgca ctccatgcat tattggctca gtagccaatt tttgtcacgt     6600

cgttataaca aggagatgac ataattaaac atttccatcc tttctattcc ctgagactgc     6660

atcagcacag gcaagtatag aatgtaatgt tcttcatggg ccccaccagc tttttggtgc     6720

catgtaattt atttcttcgc tgaagagaaa aagaattctg agacacagtt attaaaccct     6780

ttatcaactt tctaccatca gtgcctgaat tctaatgcag tgtgatttct ctgggacaaa     6840

gagactgagg aagatgaaaa gtttcttcaa agagtgaata catacttatt cacaactcta     6900

ggatgtgagg actttaaata tctctttatg aagttccctg cctaacctct ttctatttaa     6960

aggcaaacaa atttcgaaga ggttttgtgt tccctcttta tgtttctcta tgacccagtt     7020

tagtctaaaa ccttagttca ttacatatac aacacatagc ctttgatccc tggtaactgg     7080

caggtgttgg tgattaataa accaaggctt caaagtgaag tatgtgtgtg cagatgactt     7140

ttggaataac gtgggcatag catcatacct tcctgattgt cttcagcata taaaaattaa     7200

ctgttgtagt taaaattatg tcagtgcaga gcttgtggtt acttggaatg ttctttcaga     7260

atagtccatg ttgcctatta aacctagttt taaacacatt gggcagtcaa tttatgcacc     7320

caaaatatca ccctcaggta gattgagggc aagataaaat gctgtatgta gctatacaaa     7380

ggaattcaga aacattactg gaaagcaaag cctttgtcag cttgctactg acaaagtagt     7440

aaaaagctac taatcagtgt tgagtcagat gtcaacagaa aaatacaaat acctatgaga     7500

gccacagcag tttctcgttt catagccgat tcaatgaata tgattagaaa ttcactgagc     7560

tcactcttgc aggtttaaat ggaggcctgc ataaggactg caagaggaaa tctgggtggg     7620

agagaatgta atctgatctt gcactcatag gcaatgctgc aatgcaatca tgtccaatac     7680

aagcacagct tcattcataa caggaaacgt cttctttggg aaaatagctc tattggtgcc     7740

caaactcagg tatgccagtg tatgcaggtg gagtcgccct acccctcttc caaacatgtc     7800

ctgtgagatt tttaaaataa gatgggatag tacaggggca tgaaaagaat tgattccttc     7860

acaggatttg aatccagttc aagggagaat gtagaaaatt caaaaccaac atataaggta     7920

tcacacaacc aagaaaagta aaaccattgc aagtttactt gcgttgagta caaaacagat     7980

ttaatggtgt tctatgtcat agtttaatgc tctgggtatt taaatatgtt ttcaacagga     8040

tttgagttga aagtttgtaa tgtgctttga tggaacacct ctcaatttct attcaataaa     8100

cttatgtaat tgtccattga caatataatg ataacagtac cattgaactc taaactgtgg     8160

tttatcttca ctactgggaa gcaactgtgc atcagtatta aagatatgca gaaacataat     8220

attcactaat ttgttcatct gcttctgtat attgtttatg gaattacatg gcaagaactg     8280

ttctaaagca acatgtcttt ccacattatt ttagaggtga aattactttt gttttgcttc     8340

tctataatgt gtacttcaaa tgaaacacca tacttttttc taaaaaaaga tgttcaattt     8400

actaattttt ttaaatctca taatttaaaa agcatttgtt gtgattttaa agtgttgcaa     8460

gaaaagggat tttgtggccg tgggtagact ttttatactt tgttttatag atggattttt     8520

tttaactgta gtttgtttaa gtcaccaagc agcatccaaa atcttaatgt gtttcatttg     8580

atgttgttag atcagagaag aaattggcat aaaatcggtt aatagtattg tcaaagaatt     8640

gtgtattgtg tactcactgg gaaaaaataa aatatattca catttcaaa                 8689


<210>  2536
<211>  1558
<212>  DNA
<213>  homo sapiens

<400>  2536
agcagcagcc cgacgcaaga ggcaggaagc gcagcaactc gtgtctgagc gcccggcgga       60

aaaccgaagt tggaagtgtc tcttagcagc gcgcggagaa gaacggggag ccagcatcat      120

ggcagaacag gatgtggaaa acgatctttt ggattacgat gaagaggaag agccccaggc      180

tcctcaagag agcacaccag ctccccctaa gaaagacatc aagggatcct acgtttccat      240

ccacagctct ggcttccggg actttctgct gaagccggag ctcctgcggg ccatcgtgga      300

ctgtggcttt gagcatcctt ctgaggtcca gcatgagtgc attccccagg ccatcctggg      360

catggacgtc ctgtgccagg ccaagtccgg gatgggcaag acagcggtct tcgtgctggc      420

caccctacag cagattgagc ctgtcaacgg acaggtgacg gtcctggtca tgtgccacac      480

gagggagctg gccttccaga tcagcaagga atatgagcgc ttttccaagt acatgcccag      540

cgtcaaggtg tctgtgttct tcggtggtct ctccatcaag aaggatgaag aagtgttgaa      600

gaagaactgt ccccatgtcg tggtggggac cccgggccgc atcctggcgc tcgtgcggaa      660

taggagcttc agcctaaaga atgtgaagca ctttgtgctg gacgagtgtg acaagatgct      720

ggagcagctg gacatgcggc gggatgtgca ggagatcttc cgcctgacac cacacgagaa      780

gcagtgcatg atgttcagcg ccaccctgag caaggacatc cggcctgtgt gcaggaagtt      840

catgcaggat cccatggagg tgtttgtgga cgacgagacc aagctcacgc tgcacggcct      900

gcagcagtac tacgtcaaac tcaaagacag tgagaagaac cgcaagctct ttgatctctt      960

ggatgtgctg gagtttaacc aggtgataat cttcgtcaag tcagtgcagc gctgcatggc     1020

cctggcccag ctcctcgtgg agcagaactt cccggccatc gccatccacc ggggcatggc     1080

ccaggaggag cgcctgtcac gctatcagca gttcaaggat ttccagcggc ggatcctggt     1140

ggccaccaat ctgtttggcc gggggatgga catcgagcga gtcaacatcg tctttaacta     1200

cgacatgcct gaggactcgg acacctacct gcaccgggtg gcccgggcgg gtcgctttgg     1260

caccaaaggc ctagccatca cttttgtgtc tgacgagaat gatgccaaaa tcctcaatga     1320

cgtccaggac cggtttgaag ttaatgtggc agaacttcca gaggaaatcg acatctccac     1380

atacatcgag cagagccggt aaccaccacg tgccagagcc gcccacccgg agccgcccgc     1440

atgcagcttc acctcccctt tccaggcgcc actgttgaga agctagagat tgtatgagaa     1500

taaacttgtt attatggaag cctggctccc accccatcta aaaaaaaaaa aaaaaaaa       1558


<210>  2537
<211>  1558
<212>  DNA
<213>  homo sapiens

<400>  2537
agcagcagcc cgacgcaaga ggcaggaagc gcagcaactc gtgtctgagc gcccggcgga       60

aaaccgaagt tggaagtgtc tcttagcagc gcgcggagaa gaacggggag ccagcatcat      120

ggcagaacag gatgtggaaa acgatctttt ggattacgat gaagaggaag agccccaggc      180

tcctcaagag agcacaccag ctccccctaa gaaagacatc aagggatcct acgtttccat      240

ccacagctct ggcttccggg actttctgct gaagccggag ctcctgcggg ccatcgtgga      300

ctgtggcttt gagcatcctt ctgaggtcca gcatgagtgc attccccagg ccatcctggg      360

catggacgtc ctgtgccagg ccaagtccgg gatgggcaag acagcggtct tcgtgctggc      420

caccctacag cagattgagc ctgtcaacgg acaggtgacg gtcctggtca tgtgccacac      480

gagggagctg gccttccaga tcagcaagga atatgagcgc ttttccaagt acatgcccag      540

cgtcaaggtg tctgtgttct tcggtggtct ctccatcaag aaggatgaag aagtgttgaa      600

gaagaactgt ccccatgtcg tggtggggac cccgggccgc atcctggcgc tcgtgcggaa      660

taggagcttc agcctaaaga atgtgaagca ctttgtgctg gacgagtgtg acaagatgct      720

ggagcagctg gacatgcggc gggatgtgca ggagatcttc cgcctgacac cacacgagaa      780

gcagtgcatg atgttcagcg ccaccctgag caaggacatc cggcctgtgt gcaggaagtt      840

catgcaggat cccatggagg tgtttgtgga cgacgagacc aagctcacgc tgcacggcct      900

gcagcagtac tacgtcaaac tcaaagacag tgagaagaac cgcaagctct ttgatctctt      960

ggatgtgctg gagtttaacc aggtgataat cttcgtcaag tcagtgcagc gctgcatggc     1020

cctggcccag ctcctcgtgg agcagaactt cccggccatc gccatccacc ggggcatggc     1080

ccaggaggag cgcctgtcac gctatcagca gttcaaggat ttccagcggc ggatcctggt     1140

ggccaccaat ctgtttggcc gggggatgga catcgagcga gtcaacatcg tctttaacta     1200

cgacatgcct gaggactcgg acacctacct gcaccgggtg gcccgggcgg gtcgctttgg     1260

caccaaaggc ctagccatca cttttgtgtc tgacgagaat gatgccaaaa tcctcaatga     1320

cgtccaggac cggtttgaag ttaatgtggc agaacttcca gaggaaatcg acatctccac     1380

atacatcgag cagagccggt aaccaccacg tgccagagcc gcccacccgg agccgcccgc     1440

atgcagcttc acctcccctt tccaggcgcc actgttgaga agctagagat tgtatgagaa     1500

taaacttgtt attatggaag cctggctccc accccatcta aaaaaaaaaa aaaaaaaa       1558


<210>  2538
<211>  5121
<212>  DNA
<213>  homo sapiens

<400>  2538
acaaaggcgc ccgcccgccg cccgccgccc gcgcccgcgc cgccgccatg aagccggggc       60

cgccgcaccg tgccggggcc gcccacgggg ccggcgccgg ggccggggcc gcggccgggc      120

ccggggcccg cgggctgctc ctgccaccgc tgctgctgct gctgctggcg gggcgcgccg      180

cgggggccca gcgctggcgc agtgagaact tcgagagacc cgtggacctg gagggctctg      240

gggatgatga ctcctttccc gatgatgaac tggatgacct ctactcgggg tcgggctcgg      300

gctacttcga gcaggagtcg ggcattgaga cagccatgcg cttcagccca gatgtagccc      360

tggcggtgtc caccacacct gcggtgctgc ccaccacgaa catccagcct gtgggcacac      420

catttgaaga gctcccctct gagcgcccca ccctggagcc agccaccagc cccctggtgg      480

tgacagaagt cccggaagag cccagccaga gagccaccac cgtctccact accatggcta      540

ccactgctgc cacaagcaca ggggacccga ctgtggccac agtgcctgcc acagtggcca      600

ccgccacccc cagcacccct gcagcacccc cttttacggc caccactgct gttataagga      660

ccactggcgt acggaggctt ctgcctctcc cactgaccac agtggctacg gcacgggcca      720

ctacccccga ggcgccctcc ccgcccacca cggcggctgt cttggacacc gaggccccaa      780

cacccaggct ggtcagcaca gctacctccc ggccaagagc ccttcccagg ccggccacca      840

cccaggagcc tgacatccct gagaggagca ccctgcccct ggggaccact gcccctggac      900

ccacagaggt ggctcagacc ccaactccag agaccttcct gaccacaatc cgggatgagc      960

cagaggttcc ggtgagtggg gggcccagtg gagacttcga gctgccagaa gaagagacca     1020

cacaaccaga cacagccaat gaggtggtag ctgtgggagg ggctgcggcc aaggcatcat     1080

ctccacctgg gacactgccc aagggtgccc gcccgggccc tggcctcctg gacaatgcca     1140

tcgactcggg cagctcagct gctcagctgc ctcagaagag tatcctggag cggaaggagg     1200

tgctcgtagc tgtgattgtg ggcggggtgg tgggcgccct ctttgctgcc ttcttggtca     1260

cactgctcat ctatcgtatg aagaaaaagg atgagggcag ctacacgctg gaggaaccca     1320

agcaggcgag cgtcacatac cagaagcctg acaagcagga ggagttctat gcctagtgga     1380

gccacagtgc ctccctgcag cctcaacacc accctgctgt ccagtcccca gcctggcccc     1440

accagcccaa gcctgggact gggcctggaa cctggcccca gttcttctct gccctctctc     1500

ccaaggtctg cccaggctgc cagcctcaca cagatcttcc ccgaggaaga ggggctgctg     1560

ccatctgccc cagactgtgc ccttacgagc tcatctcttg ttcccctcat ccctgccacc     1620

agtctggggc ttcaggacct catgtcagat ggatgggagg aagaaagctc ctgattggct     1680

ggtggtggaa gaaagggtgg ggcttgagat gagcctgagc cctgacttgg cacccacagt     1740

gctcactgag atctcctttt tggggcagag aggcactcag gctggtttcc aggacaaaca     1800

tttggtaaac acagcccttg aaatcatcta gacactgcaa cctcttgctc gtatcccagg     1860

gcctctctct agctgggtga gagggtgtcc cttgtcacca gcctgttttg tcctggtctc     1920

tctggggttg ttgaatctct cctcttgcct gccaagtaca catgtaccca gacttcattt     1980

ctttctgcat cttcccccaa gaaacagctt cctgagggtg ctggggcagc cactggtgag     2040

gaggggctgc tctgatgtcc ctcctatgag gggactctgc acagacacca ttgcccacac     2100

tatcaccata ttttcactca gtcacacaca agacaaaagc atgcaatgac aaaaccatac     2160

gcaatcctga ccgcccagcc aatcaagaca tatcacagaa cacacgcgtc cttccaagaa     2220

tgtttatcct catgcatcac ttacacaccc ccagacacgt actgcaatgc aagtcactag     2280

tcatggtcac atgacagtga cagtgtggcc tcctcctacc ccaaatacac ccacactctg     2340

gcaccacaca cattgtctcc agctttcagg cttactgggg agggtggaat cgagccagaa     2400

caatcagccc atattgggtc cccctaagtt gccccgtcat actcagtccc atgccatggt     2460

gcccacacca accatgcagc cgccaacccc agccagtgtc agacacaatc ccatgtggat     2520

gcacagtctc actccacatg acctgctctc aatgctggag ggaaacaggc aggcccttgc     2580

ctttctcgga aaaagtgtgg ggccacagcc cttttagggc attgcatgca ggtgggcctg     2640

gcttcacccc tacctgcttc ctccccaccg cagctggcag agggggaggt ttggggccag     2700

acccccacta gctgggagcc tgggggctcc tctaaggctg aggaaggaaa tttggcccca     2760

ggttgttggg gggtcttggg tctcccagga cggaaggccc agggcaggga gggggcatgt     2820

ggttgggctc ctttatctcc ctgtgtcccc ttcctgcttt gagctagggg gctgactctg     2880

cctcccagga cacaagtctc caaagtgcct gtgagggcgg gccctccgca ccctctgccc     2940

tctgcctggc aggccaacct cagcccacct gcccagaggc cctccctgtg gacaccccct     3000

cacctatttg gccaaacaat tctggctgca gcttcagggg ccatggctgg aagcagcccc     3060

tgcagatccc tcaggccccg aggtcagggt ttgagggatg agaccaggtg atagtggggg     3120

aggggttact tcctttgtta cctagcaagt agggctattt ccatcggtat tttaaatgtg     3180

gggtcacaga tcttttgggg agggtgtgct tggcaggggg cctcttggag ccaaagggat     3240

gtggtgtgag ttgcgattgg ctggcactca cacccccacc cctcacccac atcccagatt     3300

caagtcagga aggcaggttt tatttcaggg cccttttcaa gatgccctgg cagcagattt     3360

ctgcaggatg aggggtagcg gtgtgtaggc agtgaggggg aggttccagg ggctgtccca     3420

cagcctgtct tttccaggct gggctccatc ttccagtccc aaaaccctcc ttcacagggc     3480

ccagaggctt gtgaggaagc caggtggacc cagccttaga agagtgggca tggggggccc     3540

ctgatatctg gagggggcgg gttggcctca gtcatctttg gagcagaagg gctgggtcct     3600

ggggccacag accacaaggc tcagcctccc taccctgctc cctggggtgc tgctgtcttg     3660

gagagcacag ctctggtgag acggcctggg caggccgagg ctgagaaacc agggaggata     3720

gaggagaaaa gggcttgggc ccccagcccc agaagatgct ggaccccagg tgggagaccc     3780

aacagtgggt gcagtttctc agtagggctg gagccaatgg tgggggtggc cccggcaggc     3840

ctggctcctc acatcccagg ggttggcttc tgatttgggg cttgggctcc aggcactggc     3900

ttctcttctc tgtgtcctta gcatttgaga gaagaggcca ggggccttgt tcatggatcc     3960

ctggacccaa ggcagatgtc caggctttat cctcctgagg atgaggagtc tgaccagccc     4020

aaatctgccc tggccggcct gaccggggca aggcagtcca agagagttca gtgaggacca     4080

gctaggctct cccaggtgca atgtgggtgc agggccctca tgtcccccta cccctgcctg     4140

tgatggagtg ttctgagggg ctttggcatt tgctggaagc acagggagtt ccaaatgaga     4200

gggagcttct gtggcttgag agcctctggg gccttggctg ccagagcacg aggcaggcca     4260

ggacctggag agcccagacc ctgtctccag gaggccagga ggccagatgg gggccttgcc     4320

tgaaagactg gtccccttga tcgctggagg catgtgggtg gcaaccaggg ctgggcaggg     4380

cttagggtgt gtgggccaaa cccccctggg gttggcaaag ccgcctgtca ggcctcctgg     4440

tgggggcccc tggacacagg gagcagaccc tctgcctcat ggggtaggag tggctgcctc     4500

ctgtgttctc tggatttctt ctcccaacaa ctacaaccct ggacttgcct ccccaggcct     4560

cttgcctgta aatagaagcc cgcaaactgt acagatttac agaggcatcg agactgggcc     4620

ctgggagttg ccatctgaga gccgatggcc ccagcatccc ccaggtgcct gcctggcacc     4680

acagtgaccc tggcctcagc gtggcaaatg catgtaaata tttttcgtag gcagcgtggc     4740

tccagagagc cccctgaaga cagtgtccct ccctcctgtg agtcctttct cctgtacaga     4800

acctgcctgg ggtgggtggg ggtctgccat tccctccccc aggccttccc tgccccttct     4860

ctcccctgta acctgtttat taaccatacc tgtcctgagt tcatggccaa aaccttaaat     4920

aagaaaaaca aaagaaaaag acagtggaaa aaagagacca aggcgcctgc cccactgcgg     4980

gtactctcct gttccagcct tgtgaaggaa ctggttttgt ttttgttttt tttttttttt     5040

tttttttttt gtttgtttgt ttttttaaca cttcctgtgc tgtgcccatt tataagagga     5100

aataaaatta agctgaaatg a                                               5121


<210>  2539
<211>  4373
<212>  DNA
<213>  homo sapiens

<400>  2539
agagtgggca ggccgggggt gagggctcgc gctccgggag ctgcacgggg ctgcgtggaa       60

agagcgccga gcggtggcgt cgttgtcgcc ccctcctcgt cgggaagaat cgtttggtct      120

cctgccgtgc ccggttcgta ttccctactc cctgccacga gccgccccgt ccgggatcct      180

ccacccgtcc aaagttgtga gggggcgccg ggcgtgctcg cggatcggcg gccgcgggcg      240

tgcggagggc tggacgagcc ctggagcgcc aggagaatgt gtgtgtgtcc cgggcccaga      300

cgaattggaa tcccagtcag aagttccagc ctgccactgt tctctgatgc catgccagca      360

ccaactcaac tgttttttcc tctcatccgt aactgtgaac tgagcaggat ctatggcact      420

gcatgttact gccaccacaa acatctctgt tgttcctcat cgtacattcc tcagagtcga      480

ctgagataca cacctcatcc agcatatgct accttttgca ggccaaagga gaactggtgg      540

cagtacaccc aaggaaggag atatgcttcc acaccacaga aattttacct cacacctcca      600

caagtcaata gcatccttaa agctaatgaa tacagtttca aagtgccaga atttgacggc      660

aaaaatgtca gttctatcct tggatttgac agcaatcagc tgcctgcaaa tgcacccatt      720

gaggaccgga gaagtgcagc aacctgcttg cagaccagag ggatgctttt gggggttttt      780

gatggccatg caggttgtgc ttgttcccag gcagtcagtg aaagactctt ttattatatt      840

gctgtctctt tgttacccca tgagactttg ctagagattg aaaatgcagt ggagagcggc      900

cgggcactgc tacccattct ccagtggcac aagcacccca atgattactt tagtaaggag      960

gcatccaaat tgtactttaa cagcttgagg acttactggc aagagcttat agacctcaac     1020

actggtgagt cgactgatat tgatgttaag gaggctctaa ttaatgcctt caagaggctt     1080

gataatgaca tctccttgga ggcgcaagtt ggtgatccta attcttttct caactacctg     1140

gtgcttcgag tggcattttc tggagccact gcttgtgtgg cccatgtgga tggtgttgac     1200

cttcatgtgg ccaatactgg cgatagcaga gccatgctgg gtgtgcagga agaggacggc     1260

tcatggtcag cagtcacgct gtctaatgac cacaatgctc aaaatgaaag agaactagaa     1320

cggctgaaat tggaacatcc aaagagtgag gccaagagtg tcgtgaaaca ggatcggctg     1380

cttggcttgc tgatgccatt tagggcattt ggagatgtaa agttcaaatg gagcattgac     1440

cttcaaaaga gagtgataga atctggccca gaccagttga atgacaatga atataccaag     1500

tttattcctc ctaattatca cacacctcct tatctcactg ctgagccaga ggtaacttac     1560

caccgattaa ggccacagga taagtttctg gtgttggcta ctgatgggtt gtgggagact     1620

atgcataggc aggatgtggt taggattgtg ggtgagtacc taactggcat gcatcaccaa     1680

cagccaatag ctgttggtgg ctacaaggtg actctgggac agatgcatgg ccttttaaca     1740

gaaaggagaa ccaaaatgtc ctcggtattt gaggatcaga acgcagcaac ccatctcatt     1800

cgccacgctg tgggcaacaa cgagtttggg actgttgatc atgagcgcct ctctaaaatg     1860

cttagtcttc ctgaagagct tgctcgaatg tacagagatg acattacaat cattgtagtt     1920

cagttcaatt ctcatgttgt aggggcgtat caaaaccaag aatagtgagt ggctctttca     1980

ctggcaattc tcaaatgata tacatttaaa gggcagattt tttaaaaaga tactactata     2040

ataaacattt ccagttggtc attctaagca tttacccttt tgatactcta gctagtcagg     2100

tactccaaat tgactttgca gcagggtggc agggtcagga gagtctggtc ctgcctagct     2160

cagatttcat ggcacctgca cttgaagcaa gtcacttctt tatcacaggt gtcttgaaac     2220

attagcttct tttaccaacc tgagaaaatt aggatgacct ggcaaataag atcttgaata     2280

ggccaaaagc aagtatcttg ctgtgtgtag tctcttggtt aaagtgaaga aacagtactg     2340

ttcacacctt tcttcactga gattccagtg tacatgagaa catatattta ttgcatgatt     2400

ttctagatac acagtctatg cattattcat atacatttat tttagcctaa agtggttttc     2460

aaatccagtt cttcaagcca taaatgacca agatccaagc aatctgaatt tgtttttgtg     2520

attatttgac tggaatgctt cttaagtgga ataactatac tccgttatcc acccgatttc     2580

ctaatgtaat tgaaagattt tctattttgc cacacacttg gagacaataa gggtttttag     2640

ttttatctac tcttctattg aagttaaaga aagaaaaaaa gattttttta tttgtattaa     2700

tgaaaagctt tagtttaaaa taaggagatc cagaataaaa agaagagact gatctcttca     2760

attattgtca tctgtagcca ccagcacatc actcttatgt aatccccaaa ggcttggcat     2820

gccgtaagtg tgtggtgggt agactgctgc cggggaatcg tacttcttat ttagtaatga     2880

taagactttt cattattttt ggaattttaa agatgacata aataagttta aatatcaatt     2940

tggggagtaa ggtttaatat tgccatcggg tattgagaca ggaggaagtt tctgtttttc     3000

tccatttaga cataggtcaa ttaaaatatt tgggtttaaa atgactaaat gctttaaaca     3060

tattgtagct taagatatat gtgttaagat atatacatga gaaactttaa aaggtaacta     3120

ctgtgcatgc ctgatgctta atagaatact tagtggcatc aaatgtttgc agcagtctcc     3180

ataattatat tcagtccctt ctaatactgt atcaatgtaa atgaaataaa tatattcaaa     3240

ttggcttttt gatatgcatc aagtggcatt ttgttcctgt gtttaatagt gatctgtata     3300

cagctgtgca catattgtca tcacttattc tagcatcact gttaaggctg tgattatgtt     3360

tgatattcac ctggatttta atacaagcca atatcagctt cccattgtgt aataacttgg     3420

gtgtttagga gtcttttcac attttttggg gatatgaact agatgttcaa gaactccttc     3480

tggactgtgg atactgaatc agtgtactat tggctgcaga atttgtttca attgaaaata     3540

gactcaggaa gattgctgct cagaatatca tataatgttt attttttgag gtgtttttgt     3600

ttttatttgt gtgttttttt ttttttaagt cagcttggaa cttttttcct gggtagtatt     3660

tgggagaggg aaaggctgta ctatatattt atttctaaat gttttgactg ggcatttttc     3720

ttttaatgaa atatgtggac tgctctagca aaccctattt tcagctacta tttgaatatt     3780

cttgaacacc accactgaag agtttcatat acaccaaata atgtctcatc tctatagtac     3840

agggaatata aaattggttt cctgtggtca tgatcaagat agtagtatta ttacacaaga     3900

aacttggtct gcagtctgga agcttgtctg ctctatagaa atgaaaatgc agcatgaagt     3960

tgacattgtg gaaatgaaag taattgggta ttagaaatct gaaagtactg tcatctaaaa     4020

gcaattgtga ttttattgta attggttgtc actgttgtac ggtgtctaga attaaagaat     4080

acatgtaaac tttcatggta tttagccttt cttaaatttt tttaaaattt aaactttcta     4140

acctatgtat tcaacttctg tatttatatt taatcagtgg ttcatgttat ataatacacc     4200

cttaactagt taaatggaat gttggtatgg tacagagtac catattgcta agaaaactgt     4260

cttataaaag atgtatatgt gtgaagacat gaaagtttaa tgtacagaat ggttggagaa     4320

atgcctatgg tgaattaaag cttcatatct gctttctgaa aaaaaaaaaa aaa            4373


<210>  2540
<211>  2182
<212>  DNA
<213>  homo sapiens

<400>  2540
cggaccctcc cgcggccgac tggaggcccg gagcaggggc ggagtttccg gcggcagcgc       60

cactcgggcg tcgggtgacg ctaggcggac ggaccatcat gtgacacgga agtagctccg      120

aacaggaaga ggacgaaaaa aataaccgtc cgcgacgccg agacaaaccg gacccgcaac      180

caccatgaac agcaaaggtc aatatccaac acagccaacc taccctgtgc agcctcctgg      240

gaatccagta taccctcaga ccttgcatct tcctcaggct ccaccctata ccgatgctcc      300

acctgcctac tcagagctct atcgtccgag ctttgtgcac ccaggggctg ccacagtccc      360

caccatgtca gccgcatttc ctggagcctc tctgtatctt cccatggccc agtctgtggc      420

tgttgggcct ttaggttcca caatccccat ggcttattat ccagtcggtc ccatctatcc      480

acctggctcc acagtgctgg tggaaggagg gtatgatgca ggtgccagat ttggagctgg      540

ggctactgct ggcaacattc ctcctccacc tcctggatgc cctcccaatg ctgctcagct      600

tgcagtcatg cagggagcca acgtcctcgt aactcagcgg aaggggaact tcttcatggg      660

tggttcagat ggtggctaca ccatctggtg aggaaccaag gccacctctg tgccgggaaa      720

gacatcacat accttcagca cttctcacaa tgtaactgct ttagtcatat taacctgaag      780

ttgcagttta gacacatgtt gttggggtgt ctttctggtg cccaaacttt caggcacttt      840

tcaaatttaa taaggaacca tgtaatggta gcagtacctc cctaaagcat tttgaggtag      900

gggaggtatc cattcataaa atgaatgtgg gtgaagccgc cctaaggatt ttcctttaat      960

ttctctggag taatactgta ccatactggt ctttgctttt agtaataaaa catcaaatta     1020

ggtttggagg gaactttgat cttcctaaga attaaagttg ccaaattatt ctgattggtc     1080

tttaatctcc tttaagtctt tgatatatat tacttgttat aaatggaacg cattagttgt     1140

ctgccttttc ctttccatcc cttgccccac ccatcccatc tccaacccta gtcttccatt     1200

tcctcccgcc agtctccatt gaatcaatgg tgcaggacag aaagccagtc agactaattt     1260

ccttctttcc tcgcacttct ccccactcgt catcttttaa ctagtgtttc acaaggatcc     1320

tctgaaaccc tctctgtgcc ccaagtacag atgccattac ttctgctttc gtatctcctc     1380

aggcaaaagt ggagggtgcc ttatgggccc tcctcatagg ttgtctctgc atacacgaac     1440

ctaacccaaa tttgctttgg tgccagaaaa actgagctat gtttgaacaa agatgtcgtg     1500

caaactgtac tgtgaacaac agttggttta aaatatgagg ggcaaggagg aggatgcatt     1560

tcaaaagctt gattgatgtg ttcagagcta aattaagagg agttttcaga tcaaaaactg     1620

gttaccattt tttgtcagag tgtctgatgc ggccactcat tcggctcccc agaattccta     1680

gactgggtta atagggtcat attgtgaatg tctcactaca aaatgacttg agtccagtga     1740

aatctcatta gggtttaaga atatttcagg gatccttaat gttttgattt ttgttttctg     1800

aaattggatt ttattttatt ttatcttata atttcagttc atctaaattg tgtgttctgt     1860

acatgtgatg tttgactgta ccattgactg ttatggaagt tcagcgttgt atgtctctct     1920

ctacactgtg gtgcacttaa cttgtggaat ttttatacta aaaatgtaga ataaagacta     1980

ttttgaagat ttgaataaag tgatgaagtt gcattacacc tcactgcaag gattctttac     2040

ttagcttgtt tttagatttc ttctatatat attttattta tatcccatct agaattcagc     2100

taggtgctgc tgctgctctg tttcctttga tgacgctttg aaataaaggc aggagtacaa     2160

gcctaaaaaa aaaaaaaaaa aa                                              2182


<210>  2541
<211>  5550
<212>  DNA
<213>  homo sapiens

<400>  2541
atgtctcggc gcaagcaggc caagccccag cacctcaagt cggacgagga gctgctgccg       60

cctgacgggg ctcccgagca cgccgccccg ggggaaggtg cggaggacgc agacagcggg      120

cccgagagcc gcagcggggg cgaggagacc agcgtgtgcg agaaatgctg cgccgagttc      180

ttcaagtggg cggacttcct ggagcaccag cggagctgca ccaagctccc gcccgtgctg      240

atcgtgcacg aggacgcgcc cgcgccgccc cccgaggact tccccgagcc ttcgcccgcc      300

agctccccca gcgagcgcgc cgaaagcgag gcggccgagg aggcgggtgc ggagggcgcg      360

gagggcgagg ccaggccggt ggagaaggag gccgagccca tggacgcgga acccgcgggg      420

gacacgcgcg cgccccggcc cccgcctgcg gcccctgcac ccccaacgcc cgcctacggc      480

gcgcccagca ccaacgtgac cctggaggcg ctgctgagca ccaaggtggc ggtggcgcag      540

ttctcgcagg gcgcgcgcgc ggcaggcggc tcgggagcag gtggaggcgt ggcagctgca      600

gccgtgcccc tgatcctgga acagctcatg gccctgcagc agcagcagat ccaccagctg      660

cagctcatcg agcagatccg cagccaggtg gccctcatgc agcgcccgcc gccgcggccc      720

tcactcagcc ccgcggccgc cccgagcgca ccgggcccgg cccccagcca gctgcccggg      780

ctggccgcgc tcccgctgtc ggccggggcc cctgccgccg ccatcgcggg ctcgggcccc      840

gccgccccgg ccgccttcga gggcgcgcag ccgctgtccc ggcccgagtc tggcgccagc      900

acccccggcg gccctgcgga gcccagcgcg cccgccgccc ccagcgccgc ccctgccccc      960

gctgcccccg ccccggcgcc agcgccgcag agcgcagcct cgtcgcagcc gcagagcgca     1020

tccacgccgc ctgccctggc cccggggtcc ctgctgggtg cggcgcccgg cctgccaagt     1080

ccgcttctac ctcagacttc cgccagcggc gtcatcttcc ccaacccgct ggtcagcatc     1140

gcggccacgg ccaacgctct ggacccgctg tccgcgctca tgaagcaccg caagggcaag     1200

ccgcccaatg tgtcggtgtt cgagcccaaa gccagcgccg aggacccgtt cttcaagcac     1260

aaatgccgct tctgcgccaa ggtcttcggc agcgacagcg cgctccagat ccacctgcgc     1320

tcgcacacag gcgagcggcc cttcaagtgc aacatctgcg ggaaccgctt ctccaccaaa     1380

ggcaacctga aggtgcactt ccagaggcac aaggagaagt acccccacat ccagatgaac     1440

ccttacccgg tccccgagta cctggacaac gtgcccacct gctcgggcat cccctacggc     1500

atgtcgctgc cccccgagaa gcccgtgacc acctggctgg acagcaagcc cgtgctgccc     1560

accgtgccca cgtccgtggg gctgcaactg ccgcccactg tccctggcgc gcacggctac     1620

gccgactctc ccagcgccac cccagccagc cgctccccgc agaggccctc gcccgcctcc     1680

agcgagtgcg cctccttgtc cccaggcctc aaccacgtgg agtccggcgt gtcggccacc     1740

gccgagtccc cacagtcgct cctcggcggg ccgcccctca ctaaagccga gcccgtcagc     1800

ctgccctgca ccaacgccag ggccggggac gctcccgtgg gcgcgcaggc tagcgctgca     1860

cccacatcgg tggacggcgc acccacgagc ctcggcagcc ccgggctgcc cgccgtctcc     1920

gagcagttca aggcccagtt tccgttcggg gggctgctag actcgatgca aacgtcggaa     1980

acctcgaagc tgcagcagct ggtggagaac atcgacaaga agatgacgga cccgaaccag     2040

tgcgtcatct gccaccgggt gctgagctgc cagagcgcgc tgaagatgca ctaccggacg     2100

cacacggggg agcggccgtt caagtgcaag atctgcggcc gcgccttcac caccaagggc     2160

aacctcaaga cgcacttcgg cgtgcaccgt gcaaagccgc ccctgcgcgt gcagcactcc     2220

tgccccatct gccagaagaa gttcaccaac gccgtggtcc tgcagcagca catccgcatg     2280

cacatgggcg gccagatccc caacacgccg ctgccggagg gcttccagga tgccatggac     2340

tccgagctgg cctacgacga caagaacgcg gagaccctga gcagctacga tgacgacatg     2400

gacgagaact ccatggagga cgacgctgag ctgaaggacg cggccaccga cccggccaag     2460

ccactcctgt cctacgcggg gtcctgcccg ccctccccgc cctcggtcat ctccagcatt     2520

gccgccctgg agaaccagat gaagatgatc gactcggtca tgagctgcca gcagctgacc     2580

ggcctcaagt ccgtggagaa cgggtccggg gagagtgacc gcctgagcaa cgactcctcg     2640

tcggccgtgg gcgacctgga gagccgcagc gcgggcagcc ccgccctgtc cgagtcctcg     2700

tcctcgcagg ccctgtcgcc ggcccccagc aatggtgaga gcttccgctc caagtccccg     2760

ggcctgggcg ccccggagga gccccaggaa atcccgctca agaccgagag gccggacagc     2820

ccagccgccg ccccgggcag cggaggcgcc cctggccgcg cgggcatcaa ggaggaggcg     2880

cccttcagcc tgctgttcct gagcagggag cggggtaagt gtcccagcac tgtgtgtggt     2940

gtctgtggca agccttttgc ttgcaagagc gcgttggaaa tccactaccg cagccatact     3000

aaggagcggc cattcgtctg cgcgctctgc aggcgagggt gctccactat gggtaattta     3060

aaacagcact tactgacaca cagattgaaa gagctgcctt ctcagttatt tgaccccaac     3120

tttgctctag gtcccagcca aagcactcct agcctgatct ccagcgccgc acccaccatg     3180

atcaaaatgg aagtgaacgg tcacggcaag gccatggcgc tgggcgaggg tcccccgctg     3240

cccgcgggcg tccaggtccc cgccgggcct cagacagtga tgggcccggg cctggcgccc     3300

atgctggccc ccccaccgcg ccggacgccc aagcagcaca actgccagtc gtgcgggaag     3360

accttctcct cggccagcgc cctgcagatc catgagcgca cgcacaccgg cgagaagccg     3420

ttcggctgca ccatctgcgg ccgggccttc accactaagg gcaacctcaa ggtgcacatg     3480

gggacacaca tgtggaataa cgcccccgcg agacgcggcc gccgcctgtc tgtggagaac     3540

cccatggctc tcctaggggg tgatgccctg aagttctctg aaatgttcca gaaggacctg     3600

gcagctcggg caatgaacgt cgaccccagt ttttggaacc agtatgctgc agccatcact     3660

aacgggctcg ccatgaagaa caacgagatc tccgtcatcc agaacggcgg catcccccag     3720

ctccccgtga gtcttggggg cagcgccctc ccccctctgg gcagcatggc cagtgggatg     3780

gacaaagcac gcactggcag tagcccaccc atcgtcagct tggacaaagc gagctcagaa     3840

acagcagcca gccgcccatt cacgcggttt atcgaggata acaaggagat tggtatcaac     3900

tagccagtga ctcgctcatc tgccctgccc aggcccacgt tttgaagttg gagcatcagg     3960

cctccgacct ttcttgcctc ggttctcatt acactttcac ccatagcaga aaacactttg     4020

tgcggctgcc gagaggtggt cttgtaagcg ctgcatggcg ctcccttcaa cagcaagcct     4080

gactgttctc gagaactctg caatctttta aataagcttc cttcaaaaaa aaaagtgctt     4140

ggaaaaccgc cttaggaaca gaaagagctc agaccatgtc cacttccttt ctcctgaaac     4200

ctaataatct ctccgaggga gaaaggggtt ctctgcggta ttccagtgaa actcatttga     4260

tggtttcttt tgaattagtt agacacttga acggtgtttt ttagaactct tcatgttaaa     4320

gacgtggttt agtactccca atgctgtgta tcatgacact atcttcgtct gtagtattta     4380

tgatgttaag ataatgcggg taacagacaa tataatagcc ccgaccttaa acgaagcttt     4440

tgtactgcag aatacatctg gctgtgtgat tttttttttt aagcaagatt tgttttacta     4500

taaataagtg gattatttca atgcaggcaa aattgtgaag ttctgttggg aaagatagca     4560

tgcttttcgt gtgcaagtac ctgtcagtaa taagcctttt tttttttttt ttttaattta     4620

aatgtttgta gctgctatgt ggacagttgt tttctagtgt ggtctgtagc ccaataactg     4680

gggaacgagt tacagacaaa catcaccgta aatgactcac aacattataa acagttgtga     4740

gaaaatattt cacattatca aagctgtaca ataaaaaggt aatgtttgta taatgtggtt     4800

gcaaactctt aatttatact attgcacttt tagtattttg tattagggag gtttgtctat     4860

aatttgaaaa tttaaaaaaa tgtaaagtat tttataaata gtacttcagt ttaaggaaaa     4920

tgggaaaact gttacagttc cttgttttgt cttatggtca aacaatatta gaaatctctg     4980

ccacttgaaa agccaccaag acttgtcagc ttttcagtaa agtagggcct gccgtttctt     5040

aaattaaaat gatttattta acttttccac aaagcccact ttaaaactgt gaccgccccc     5100

taacgaaacc ttggtgaatt catcctagga ctatgacgtc agtacaagcc aggaaggaac     5160

taggataacc ttctgcaggt ctgattttca tgtaagcggg tctgtctctc tctctcaccc     5220

acagacaaga ttgtggctgc ctggtggcac tggtcacatg tacagtaaac ccaagagaaa     5280

tggcaagtat caggcagtac aatcagtcat gactttgaaa ttttccgagt tcctgattta     5340

tttattatct tctcagatga aagcaaagca cagtgtcctc tgatttttca gaacacagcc     5400

tgacgctgat ggctgagctg catccagcca ggagggcccc ggaggctggg gcggccgagg     5460

cagcacaaac acggcgtcgt gaactacctc attttcgtgc gttgcaagtg tgctggcgtc     5520

tgacactatg aacttccaac aacaaaattg                                      5550


<210>  2542
<211>  1350
<212>  DNA
<213>  homo sapiens

<400>  2542
ggggacgctc tcagctctca gtgcctggcc cagcttcctt caaaatgtat actatttacg       60

aaatcctgtg caagctcagc ttggagggtc atcactctac accctcaggt gcatatgggt      120

cagtcaaagc ctacaccaac tttgatgctg agggggatgc tttgaacatt gaaaggacca      180

tcaggacaaa aggtgtgggt aagttcacca ttgtcaacat tttgaccaac agcaggaatg      240

ctcggagaga ggatgttgcc tttgcctagc agagaaggac cacaaaggaa cttacatcag      300

cactgaagtc agccttactg gccacctgga gacagtcatt ttgggcctat tgaagacacc      360

tgctcagtat gatgcttctg agctaaaagc ttccatgaag gggctgggaa ctgaggagga      420

ctccctcgtt gagatcatct gctcaacaac caaccaggag ctccaggaaa ttaacagagt      480

ctacaaagaa atgtacaaaa ctgatctgga gaaggacatt atttcggaca catatggtga      540

cttctgcaag ctgatgtttg ccctggcaaa tgttagaaga ccagaggatg gctctgtcgt      600

tgattatgaa ctgattgacc aagatgcccg ggatttctgt gatgctggag tgaagaggaa      660

aagaactgat gttcccaagt ggatcagcat gatgaccgag tagagcatgt cccacctcca      720

gaaagtattt gataggtaca agagctacag cccatcaaga gagagcatca agaaagaggt      780

taaaggagac ctggaaaatg ctttcctgaa cctggtccag tgcattcaga acaagcccct      840

gtattttgct gattggctgt actactccat gaagggccgg gggctcgaga taaggtcctg      900

atcagaatca tcgtctcccg cagtgaagtg gacatgttga aaattaggtc tgaattcaag      960

agaaagtatg gcatgtcccc gtactattac atccagcaag acactaagaa cgactaccca     1020

aaaagcactg ctgtacctgt gtggtggaga tgactgaagc ccaacatagc ttgagcttcc     1080

agaaacggtg ctccccacgc ttccagctaa caggtctaga aaaccagctt gtggctaaca     1140

gtccctgtgg ccgtccctgt gaagatgaca ttagcattgc ccccaacctc attttagttg     1200

cgtaagcata gcctggcttt cctgtctagt ctctcctgta agccaaagaa atgtacattc     1260

caagcagttg gaagtgaaat ctatgatgtg aaacactttg cctcctgtgt actgtgtcat     1320

aaacagatga ataaactgaa tttgtacttt                                      1350


<210>  2543
<211>  7327
<212>  DNA
<213>  homo sapiens

<400>  2543
acacagtact ctcagcttgt tggtggaagc ccctcatctg ccttcattct gaaggcaggg       60

cccggcagag gaaggatcag agggtcgcgg ccggagggtc ccggccggtg gggccaactc      120

agagggagag gaaagggcta gagacacgaa gaacgcaaac catcaaattt agaagaaaaa      180

gccctttgac tttttccccc tctccctccc caatggctgt gtagcaaaca tccctggcga      240

taccttggaa aggacgaagt tggtctgcag tcgcaatttc gtgggttgag ttcacagttg      300

tgagtgcggg gctcggagat ggagccgtgg tcctctaggt ggaaaacgaa acggtggctc      360

tgggatttca ccgtaacaac cctcgcattg accttcctct tccaagctag agaggtcaga      420

ggagctgctc cagttgatgt actaaaagca ctagattttc acaattctcc agagggaata      480

tcaaaaacaa cgggattttg cacaaacaga aagaattcta aaggctcaga tactgcttac      540

agagtttcaa agcaagcaca actcagtgcc ccaacaaaac agttatttcc aggtggaact      600

ttcccagaag acttttcaat actatttaca gtaaaaccaa aaaaaggaat tcagtctttc      660

cttttatcta tatataatga gcatggtatt cagcaaattg gtgttgaggt tgggagatca      720

cctgtttttc tgtttgaaga ccacactgga aaacctgccc cagaagacta tcccctcttc      780

agaactgtta acatcgctga cgggaagtgg catcgggtag caatcagcgt ggagaagaaa      840

actgtgacaa tgattgttga ttgtaagaag aaaaccacga aaccacttga tagaagtgag      900

agagcaattg ttgataccaa tggaatcacg gtttttggaa caaggatttt ggatgaagaa      960

gtttttgagg gggacattca gcagtttttg atcacaggtg atcccaaggc agcatatgac     1020

tactgtgagc attatagtcc agactgtgac tcttcagcac ccaaggctgc tcaagctcag     1080

gaacctcaga tagatgagaa aaagaaatcc aatttcaaaa agaagatgag gacagtggct     1140

actaaatcaa aggaaaaatc caaaaagttt acacccccca aatctgaaaa attttcatcc     1200

aagaagaaga aaagttatca agcatcagca aaagccaaac taggggtaaa ggcaaacatc     1260

gttgatgatt ttcaagaata caactatgga acaatggaaa gttaccagac agaagctcct     1320

aggcatgttt ctgggacaaa tgagccaaat ccagttgaag aaatatttac tgaagaatat     1380

ctaacgggag aggattatga ttcccagagg aaaaattctg aggatacact atatgaaaac     1440

aaagaaatag acggcaggga ttctgatctt ctggtagatg gagatttagg cgaatatgat     1500

ttttatgaat ataaagaata tgaagataaa ccaacaagcc cccctaatga agaatttggt     1560

ccaggtgtac cagcagaaac tgatattaca gaaacaagca taaatggcca tggtgcatat     1620

ggagagaaag gacagaaagg agaaccagca gtggttgagc ctggtatgct tgtcgaagga     1680

ccaccaggac cagcaggacc tgcaggtatt atgggtcctc caggtctaca aggccccact     1740

ggaccccctg gtgaccctgg cgataggggc cccccaggac gtcctggctt accaggggct     1800

gatggtctac ctggtcctcc tggtactatg ttgatgttac cgttccgtta tggtggtgat     1860

ggttccaaag gaccaaccat ctctgctcag gaagctcagg ctcaagctat tcttcagcag     1920

gctcggattg ctctgagagg cccacctggc ccaatgggtc taactggaag accaggtcct     1980

gtgggggggc ctggttcatc tggggccaaa ggtgagagtg gtgatccagg tcctcagggc     2040

cctcgaggcg tccagggtcc ccctggtcca acgggaaaac ctggaaaaag gggtcgtcca     2100

ggtgcagatg gaggaagagg aatgccagga gaacctgggg caaagggaga tcgagggttt     2160

gatggacttc cgggtctgcc aggtgacaaa ggtcacaggg gtgaacgagg tcctcaaggt     2220

cctccaggtc ctcctggtga tgatggaatg aggggagaag atggagaaat tggaccaaga     2280

ggtcttccag gtgaagctgg cccacgaggt ttgctgggtc caaggggaac tccaggagct     2340

ccagggcagc ctggtatggc aggtgtagat ggccccccag gaccaaaagg gaacatgggt     2400

ccccaagggg agcctgggcc tccaggtcaa caagggaatc caggacctca gggtcttcct     2460

ggtccacaag gtccaattgg tcctcctggt gaaaaaggac cacaaggaaa accaggactt     2520

gctggacttc ctggtgctga tgggcctcct ggtcatcctg ggaaagaagg ccagtctgga     2580

gaaaaggggg ctctgggtcc ccctggtcca caaggtccta ttggataccc gggcccccgg     2640

ggagtaaagg gagcagatgg tgtcagaggt ctcaagggat ctaaaggtga aaagggtgaa     2700

gatggttttc caggattcaa aggtgacatg ggtctaaaag gtgacagagg agaagttggt     2760

caaattggcc caagagggga agatggccct gaaggaccca aaggtcgagc aggcccaact     2820

ggagacccag gtccttcagg tcaagcagga gaaaagggaa aacttggagt tccaggatta     2880

ccaggatatc caggaagaca aggtccaaag ggttccactg gattccctgg gtttccaggt     2940

gccaatggag agaaaggtgc acggggagta gctggcaaac caggccctcg gggtcagcgt     3000

ggtccaacgg gtcctcgagg ttcaagaggt gcaagaggtc ccactgggaa acctgggcca     3060

aagggcactt caggtggcga tggccctcct ggccctccag gtgaaagagg tcctcaagga     3120

cctcagggtc cagttggatt ccctggacca aaaggccctc ctggaccacc tgggaaggat     3180

gggctgccag gacaccctgg gcaacgtggg gagactggat ttcaaggcaa gaccggccct     3240

cctgggccag ggggagtggt tggaccacag ggaccaaccg gtgagactgg tccaataggg     3300

gaacgtgggc atcctggccc tcctggccct cctggtgagc aaggtcttcc tggtgctgca     3360

ggaaaagaag gtgcaaaggg tgatccaggt cctcaaggta tctcagggaa agatggacca     3420

gcaggattac gtggtttccc aggggaaaga ggtcttcctg gagctcaggg tgcacctgga     3480

ctgaaaggag gggaaggtcc ccagggccca ccaggtccag ttggctcacc aggagaacgt     3540

gggtcagcag gtacagctgg cccaattggt ttaccagggc gcccgggacc tcagggtcct     3600

cctggtccag ctggagagaa aggtgctcct ggagaaaaag gtccccaagg gcctgcaggg     3660

agagatggag ttcaaggtcc tgttggtctc ccagggccag ctggtcctgc cggctcccct     3720

ggggaagacg gagacaaggg tgaaattggt gagccgggac aaaaaggcag caagggtgac     3780

aagggagaaa atggccctcc cggtccccca ggtcttcaag gaccagttgg tgcccctgga     3840

attgctggag gtgatggtga accaggtcct agaggacagc aggggatgtt tgggcaaaaa     3900

ggtgatgagg gtgccagagg cttccctgga cctcctggtc caataggtct tcagggtctg     3960

ccaggcccac ctggtgaaaa aggtgaaaat ggggatgttg gtcccatggg gccacctggt     4020

cctccaggcc caagaggccc tcaaggtccc aatggagctg atggaccaca aggaccccca     4080

gggtctgttg gttcagttgg tggtgttgga gaaaagggtg aacctggaga agcagggaac     4140

ccagggcctc ctggggaagc aggtgtaggc ggtcccaaag gagaaagagg agagaaaggg     4200

gaagctggtc cacctggagc tgctggacct ccaggtgcca aggggccacc aggtgatgat     4260

ggccctaagg gtaacccggg tcctgttggt tttcctggag atcctggtcc tcctggggaa     4320

cctggccctg caggtcaaga tggtgttggt ggtgacaagg gtgaagatgg agatcctggt     4380

caaccgggtc ctcctggccc atctggtgag gctggcccac caggtcctcc tggaaaacga     4440

ggtcctcctg gagctgcagg tgcagaggga agacaaggtg aaaaaggtgc taagggggaa     4500

gcaggtgcag aaggtcctcc tggaaaaacc ggcccagtcg gtcctcaggg acctgcagga     4560

aagcctggtc cagaaggtct tcggggcatc cctggtcctg tgggagaaca aggtctccct     4620

ggagctgcag gccaagatgg accacctggt cctatgggac ctcctggctt acctggtctc     4680

aaaggtgacc ctggctccaa gggtgaaaag ggacatcctg gtttaattgg cctgattggt     4740

cctccaggag aacaagggga aaaaggtgac cgagggctcc ctggaactca aggatctcca     4800

ggagcaaaag gggatggggg aattcctggt cctgctggtc ccttaggtcc acctggtcct     4860

ccaggtttac caggtcctca aggcccaaag ggtaacaaag gctctactgg acccgctggc     4920

cagaaaggtg acagtggtct tccagggcct cctgggtctc caggtccacc tggtgaagtc     4980

attcagcctt taccaatctt gtcctccaaa aaaacgagaa gacatactga aggcatgcaa     5040

gcagatgcag atgataatat tcttgattac tcggatggaa tggaagaaat atttggttcc     5100

ctcaattccc tgaaacaaga cattgagcat atgaaatttc caatgggtac tcagaccaat     5160

ccagcccgaa cttgtaaaga cctgcaactc agccatcctg acttcccaga tggtgaatat     5220

tggattgatc ctaaccaagg ttgctcagga gattccttca aagtttactg taatttcaca     5280

tctggtggtg agacttgcat ttatccagac aaaaaatctg agggagtaag aatttcatca     5340

tggccaaagg agaaaccagg aagttggttt agtgaattta agaggggaaa actgctttca     5400

tacttagatg ttgaaggaaa ttccatcaat atggtgcaaa tgacattcct gaaacttctg     5460

actgcctctg ctcggcaaaa tttcacctac cactgtcatc agtcagcagc ctggtatgat     5520

gtgtcatcag gaagttatga caaagcactt cgcttcctgg gatcaaatga tgaggagatg     5580

tcctatgaca ataatccttt tatcaaaaca ctgtatgatg gttgtgcgtc cagaaaaggc     5640

tatgaaaaga ctgtcattga aatcaataca ccaaaaattg atcaagtacc tattgttgat     5700

gtcatgatca atgactttgg tgatcagaat cagaagttcg gatttgaagt tggtcctgtt     5760

tgttttcttg gctaagatta agacaaagaa catatcaaat caacagaaaa tataccttgg     5820

tgccaccaac ccattttgtg ccacatgcaa gttttgaata aggatggtat agaaaacaac     5880

gctgcatata caggtaccat ttaggaaata ccgatgcctt tgtgggggca gaatcacatg     5940

gcaaaagctt tgaaaatcat aaagatataa gttggtgtgg ctaagatgga aacagggctg     6000

attcttgatt cccaattctc aactctcctt ttcctatttg aatttctttg gtgctgtaga     6060

aaacaaaaaa agaaaaatat atattcataa aaaatatggt gctcattctc atccatccag     6120

gatgtactaa aacagtgtgt ttaataaatt gtaattattt tgtgtacagt tctatactgt     6180

tatctgtgtc catttccaaa acttgcacgt gtccctgaat tccatctgac tctaatttta     6240

tgagaattgc agaactctga tggcaataaa tatatgtatt atgaaaaaat aaagttgtaa     6300

tttctgatga ctctaagtcc ctttctttgg ttaataataa aatgcctttg tatatattga     6360

tgttgaagag ttcaattatt tgatgtcgcc aacaaaattc tcagagggca aaaatctgga     6420

agacttttgg aagcacactc tgatcaactc ttctctgccg acagtcattt tgctgaattt     6480

cagccaaaaa tattatgcat tttgatgctt tattcaaggc tatacctcaa actttttctt     6540

ctcagaatcc aggatttcac aggatacttg tatatatgga aaacaagcaa gtttatattt     6600

ttggacaggg aaatgtgtgt aagaaagtat attaacaaat caatgcctcc gtcaagcaaa     6660

caatcatatg tatacttttt ttctacgtta tctcatctcc ttgttttcag tgtgcttcaa     6720

taatgcaggt taatattaaa gatggaaatt aagcaattat ttatgaattt gtgcaatgtt     6780

agattttctt atcaatcaag ttcttgaatt tgattctaag ttgcatatta taacagtctc     6840

gaaaattatt ttacttgccc aacaaatatt acttttttcc tttcaagata attttataaa     6900

tcatttgacc tacctaattg ctaaatgaat aacatatggt ggactgttat taagagtatt     6960

tgttttaagt cattcaggaa aatctaaact tttttttcca ctaaggtatt tactttaagg     7020

tagcttgaaa tagcaataca atttaaaaat taaaaactga attttgtatc tattttaagt     7080

aatatatgta agacttgaaa ataaatgttt tatttcttat ataaagtgtt aaattaattg     7140

ataccagatt tcactggaac agtttcaact gataatttat gacaaaagaa catacctgta     7200

atattgaaat taaaaagtga aatttgtcat aaagaatttc ttttattttt gaaatcgagt     7260

ttgtaaatgt ccttttaaga agggagatat gaatccaata aataaactca agtcttggct     7320

acctgga                                                               7327


<210>  2544
<211>  2379
<212>  DNA
<213>  homo sapiens

<400>  2544
gacccccgag ctgtgctgct cgcggccgcc accgccgggc cccggccgtc cctggctccc       60

ctcctgcctc gagaagggca gggcttctca gaggcttggc gggaaaaaga acggagggag      120

ggatcgcgct gagtataaaa gccggttttc ggggctttat ctaactcgct gtagtaattc      180

cagcgagagg cagagggagc gagcgggcgg ccggctaggg tggaagagcc gggcgagcag      240

agctgcgctg cgggcgtcct gggaagggag atccggagcg aatagggggc ttcgcctctg      300

gcccagccct cccgctgatc ccccagccag cggtccgcaa cccttgccgc atccacgaaa      360

ctttgcccat agcagcgggc gggcactttg cactggaact tacaacaccc gagcaaggac      420

gcgactctcc cgacgcgggg aggctattct gcccatttgg ggacacttcc ccgccgctgc      480

caggacccgc ttctctgaaa ggctctcctt gcagctgctt agacgctgga tttttttcgg      540

gtagtggaaa accagcagcc tcccgcgacg atgcccctca acgttagctt caccaacagg      600

aactatgacc tcgactacga ctcggtgcag ccgtatttct actgcgacga ggaggagaac      660

ttctaccagc agcagcagca gagcgagctg cagcccccgg cgcccagcga ggatatctgg      720

aagaaattcg agctgctgcc caccccgccc ctgtccccta gccgccgctc cgggctctgc      780

tcgccctcct acgttgcggt cacacccttc tcccttcggg gagacaacga cggcggtggc      840

gggagcttct ccacggccga ccagctggag atggtgaccg agctgctggg aggagacatg      900

gtgaaccaga gtttcatctg cgacccggac gacgagacct tcatcaaaaa catcatcatc      960

caggactgta tgtggagcgg cttctcggcc gccgccaagc tcgtctcaga gaagctggcc     1020

tcctaccagg ctgcgcgcaa agacagcggc agcccgaacc ccgcccgcgg ccacagcgtc     1080

tgctccacct ccagcttgta cctgcaggat ctgagcgccg ccgcctcaga gtgcatcgac     1140

ccctcggtgg tcttccccta ccctctcaac gacagcagct cgcccaagtc ctgcgcctcg     1200

caagactcca gcgccttctc tccgtcctcg gattctctgc tctcctcgac ggagtcctcc     1260

ccgcagggca gccccgagcc cctggtgctc catgaggaga caccgcccac caccagcagc     1320

gactctgagg aggaacaaga agatgaggaa gaaatcgatg ttgtttctgt ggaaaagagg     1380

caggctcctg gcaaaaggtc agagtctgga tcaccttctg ctggaggcca cagcaaacct     1440

cctcacagcc cactggtcct caagaggtgc cacgtctcca cacatcagca caactacgca     1500

gcgcctccct ccactcggaa ggactatcct gctgccaaga gggtcaagtt ggacagtgtc     1560

agagtcctga gacagatcag caacaaccga aaatgcacca gccccaggtc ctcggacacc     1620

gaggagaatg tcaagaggcg aacacacaac gtcttggagc gccagaggag gaacgagcta     1680

aaacggagct tttttgccct gcgtgaccag atcccggagt tggaaaacaa tgaaaaggcc     1740

cccaaggtag ttatccttaa aaaagccaca gcatacatcc tgtccgtcca agcagaggag     1800

caaaagctca tttctgaaga ggacttgttg cggaaacgac gagaacagtt gaaacacaaa     1860

cttgaacagc tacggaactc ttgtgcgtaa ggaaaagtaa ggaaaacgat tccttctaac     1920

agaaatgtcc tgagcaatca cctatgaact tgtttcaaat gcatgatcaa atgcaacctc     1980

acaaccttgg ctgagtcttg agactgaaag atttagccat aatgtaaact gcctcaaatt     2040

ggactttggg cataaaagaa cttttttatg cttaccatct tttttttttc tttaacagat     2100

ttgtatttaa gaattgtttt taaaaaattt taagatttac acaatgtttc tctgtaaata     2160

ttgccattaa atgtaaataa ctttaataaa acgtttatag cagttacaca gaatttcaat     2220

cctagtatat agtacctagt attataggta ctataaaccc taattttttt tatttaagta     2280

cattttgctt tttaaagttg atttttttct attgttttta gaaaaaataa aataactggc     2340

aaatatatca ttgagccaaa tcttaaaaaa aaaaaaaaa                            2379


<210>  2545
<211>  1216
<212>  DNA
<213>  homo sapiens

<400>  2545
gcccccgcct ggagtccaga cccgacggcc ggcccagttc cacgcaccca gcgagcccaa       60

gcgccttctc cgcaccaggg aagccccacc caccagaagc caagatgtcc agcaagcggg      120

ccaaagccaa gaccaccaag aagcggccac agcgggccac atccaatgtc ttcgcaatgt      180

ttgaccagtc ccagatccag gagtttaagg aggctttcaa catgattgac cagaaccgtg      240

atggcttcat tgacaaggag gacctgcacg acatgctggc ctcgctgggg aagaacccca      300

cagacgaata cctggagggc atgatgagcg aggccccggg gcccatcaac ttcaccatgt      360

tcctcaccat gtttggggag aagctgaacg gcacggaccc cgaggatgtg attcgcaacg      420

cctttgcctg cttcgacgag gaagcctcag gtttcatcca tgaggaccac ctccgggagc      480

tgctcaccac catgggtgac cgcttcacag atgaggaagt ggacgagatg taccgggagg      540

cacccattga taagaaaggc aacttcaact acgtggagtt cacccgcatc ctcaaacatg      600

gcgccaagga taaagacgac taggccaccc cagccccctg acaccccagc ccccgccagt      660

cacccctccc cgcacacacc cgtccatacc agctccctgc ccatgaccct cgctcaggga      720

tccccctttg aggggttagg gtcccagttc ccagtggaag aaacaggcca ggagaagtgc      780

gtgccgagct gaggcagatg ttcccacagt gaccccagag ccctgggcta tagtctctga      840

cccctccaag gaaagaccac cttctgggga catgggctgg agggcaggac ctagaggcac      900

caagggaagg ccccattccg gggctgttcc ccgaggagga agggaagggg ctctgtgtgc      960

cccccaggag gaagaggccc tgagtcctgg gatcagacac cccttcacgt gtatccccac     1020

acaaatgcaa gctcaccaag gtcccctctc agtccccttc cctacaccct gaccggccac     1080

tgccgcacac ccacccagag cacgccaccc gccatgggag tgtgctcagg agtcgcgggc     1140

agcgtggaca tctgtcccag agggggcaga atctccaata gaggactgag cactgctaaa     1200

aaaaaaaaaa aaaaaa                                                     1216


<210>  2546
<211>  1184
<212>  DNA
<213>  homo sapiens

<400>  2546
gcaggaccgt cattgacgcc atgagcgcgc tgctgcggct gctgcgcacg ggtgccccag       60

ccgctgcgtg cctgcggttg gggaccagtg cagggaccgg gtcgcgccgt gctatggccc      120

tgtaccacac tgaggagcgc ggccagccct gctcgcagaa ttaccgcctc ttctttaata      180

ttgatgatgt taagaagttc aaaccgggtt acctggaagc tactcttaat tggtttagat      240

tatataaggt accagatgga aaaccagaaa accagtttgc ttttaatgga gaattcaaaa      300

acaaggcttt tgctcttgaa gttattaaat ccactcatca atgttggaaa gcattgctta      360

tgaagaagtg taatggagga gctataaatt gcacaaacgt gcagatatct gatagccctt      420

tccgttgcac tcaagaggaa gcaagatcat tagttgaatc ggtatcatct tcaccaaata      480

aagaaagtaa tgaagaagag caagtgtggc acttccttgg caagtgattg aaacatctga      540

aattctgctg tcaagattcc catctctaag gactccaagt gctagagaca agggggtcta      600

tgagcattta ctgacttcct gttaaaactt cattttttca aactttttga gctatgcaat      660

atataaataa acagtaagaa ttttaaatta ctctcctttg gacatttatt gatataaaaa      720

gaagattttg gccaggcacg gtggctcatg cctgtaattt cagcactttg ggaggccgag      780

gtgggcagat cacaaggtca ggagttcaag accagcctgg ccagtatgtt gaaaccccat      840

ctctattaaa aatacaaaaa ttagccaggc gtggtggtgc atgcctgtag acccagctac      900

tcaggaggct gaggcagaag aactgcttga gcccaggagg cagaggttgc agtgagcaga      960

gattgtgcca ctgcactcca gcctaggcga cagagagaga ctccgtctca aaaaaaaaaa     1020

aaagattttg tttcatttca tagcacaaat ttagaggcat tgagttgacc atttctagtt     1080

tctatacctg aaggaaccca ttgattttac cagtttttat ttctgtagat tggatgtaaa     1140

aatcacagat tcaataaatt aataaacttt gtgtaaaaaa aaaa                      1184


<210>  2547
<211>  2003
<212>  DNA
<213>  homo sapiens

<400>  2547
gccggggtct aggcaccacg gtggctggcg gcctgcgggc ggcgctgtgg cccgtcgggc       60

ggctccacag agccgcccta gccttccgcc ttccccaagc caacgtctcc gccgtcggct      120

ccgcggcgcc gccatggccg acgtggaaga cggagaggaa acctgcgccc tggcctctca      180

ctccgggagc tcaggctcca agtcgggagg cgacaagatg ttctccctca agaagtggaa      240

cgcggtggcc atgtggagct gggacgtgga gtgcgatacg tgcgccatct gcagggtcca      300

gatgcctgtc ttagatgtca agctgaaaac aaacaagagg actgtgttgt ggtctgggga      360

gaatgtaatc attccttcca caactgctgc atgtccctgt gggtgaaaca gaacaatcgc      420

tgccctctct gccagcagga ctgggtggtc caaagaatcg gcaaatgaga gtggttagaa      480

ggcttcttag cgcagttgtt cagagccctg gtggatcttg taatccagtg ccctacaaag      540

gctagaacac tacaggggat gaattcttca aataggagcc gatggatctg tggtcctttg      600

ggactcatca aagccttggt ttagcatttt gtcagtttta tcttcagaaa ttctctgcga      660

ttaagaagat aatttattaa aggtggtcct tcctacctct gtggtgtgtg tcgcgcacac      720

agcttagaag tgctataaaa aaggaaagag ctccaaattg aatcaccttt ataatttacc      780

catttctata caacaggcag tggaagcagt ttcagagaac tttttgcatg cttatggttg      840

atcagttaaa aaagaatgtt acagtaacaa ataaagtgca gtttaaaacc caactcttac      900

tcttaatttg ttcctaatac gtatttttgg cagggagagg gaacggtcca tgaaatcttt      960

atgtgatata aggattttaa gtttgggcca gtgaacaggg taaataaaat ttaacttttg     1020

agcatatgga attttgattg cctttaaagt tactattctg tatcattgat tcatcaagaa     1080

aacctagatc tgcactcacc tcactgttca atcattgagt ggtaaaggac agaagtattt     1140

tctagttctg gtcagatgat ataatttttt tttttttttt ttgtgggggt gaagtcttgc     1200

tctgccaccc aggctggagt gcagtggcat gatgtcaact cactgcaacc tccgcctccc     1260

gggttcaagt gattctcctg cctcagcctc ccgagtagct gggattacag gtgtgtgcca     1320

ccacacccgg ctaatttttg tatttttagt agagacggga tttccccatg ttggccaggc     1380

tggtctcaaa ctcctgacct caggtgattc gcccacctca gcctcccaaa gtgctgggat     1440

tacaggtgtg ggccactgca cctggcccag atgatataat ttaactgtgt tttaggtaac     1500

atgttaatga gggaaaatgt ttaccagtgt agcattggat caaaaagttt atcacacagt     1560

gttttaataa atggtttatt ctgcttacct tatttgaatt gtcattataa ttttatatgc     1620

aaccttaatt tgtcaagtaa atactttcat ttaatttgaa agaattcata ttcatttgct     1680

ctttcatttg acaataataa aatttaaggt ttattacctg gaaagagtgc aagaaaatac     1740

taaacaactt tatcaaactg attcacactg aggggaggtt attttgtaac aaataatgga     1800

ccacaagttc attttgtatt cttctgtagt agaggctact gatatgaatt taagaaaaaa     1860

ccttagaatc ttaacttttc acatctgcag atgcagtgtg ccattctgaa tttttcaatc     1920

taagggatgt ggatacatag aatgtttaaa aagataacaa ttagaatgaa aaattaaaat     1980

tatgtatgct tttaaaaaaa aaa                                             2003


<210>  2548
<211>  2554
<212>  DNA
<213>  homo sapiens

<400>  2548
gagccgagat cgcgccaccg ccctccagcc tgggcgacag agcaagactc tgtctcaaaa       60

aaaaaaaaaa aaagagcaaa ttttttttcc aaggtgatag ggagagtccg tggctgatgt      120

ctgcactgac cagacgcccc tagggggcca gcgagggcgg gtcccaggtg cagcggatgc      180

agaggagaga ggcccgggcg cggcgcgggg gatggtgcga tcccgggccc gagggcatca      240

gacggcggct gattagctcc ggtttgcatc acccggaccg ggggattagc tccggtttgc      300

atcacccgga ccgggggatt agctccggtt tgcatcaccc ggaccggggg ccgggcgcgc      360

acgagactcg cagcggaagt ggaggcggct ccgcgcgcgt ccgctgctag gacccgggca      420

gggctggagc tgggctggga tcccgagctc ggcagcagcg cagcgggccg gcccacctgc      480

tggtgccctg gaggctctga gccccggcgg cgcccgggcc cacgcggaac gacggggcga      540

gatgcgagcc acccctctgg ctgctcctgc gggttccctg tccaggaaga agcggttgga      600

gttggatgac aacttagata ccgagcgtcc cgtccagaaa cgagctcgaa gtgggcccca      660

gcccagactg cccccctgcc tgttgcccct gagcccacct actgctccag atcgtgcaac      720

tgctgtggcc actgcctccc gtcttgggcc ctatgtcctc ctggagcccg aggagggcgg      780

gcgggcctac caggccctgc actgccctac aggcactgag tatacctgca aggtgtaccc      840

cgtccaggaa gccctggccg tgctggagcc ctatgcgcgg ctgcccccgc acaagcatgt      900

ggctcggccc actgaggtcc tggctggtac ccagctcctc tacgcctttt tcactcggac      960

ccatggggac atgcacagcc tggtgcgaag ccgccaccgt atccctgagc ctgaggctgc     1020

cgtgctcttc cgccagatgg ccaccgccct ggcgcactgt caccagcacg gtctggtcct     1080

gcgtgatctc aagctgtgtc gctttgtctt cgctgaccgt gagaggaaga agctggtgct     1140

ggagaacctg gaggactcct gcgtgctgac tgggccagat gattccctgt gggacaagca     1200

cgcgtgccca gcctacgtgg gacctgagat actcagctca cgggcctcat actcgggcaa     1260

ggcagccgat gtctggagcc tgggcgtggc gctcttcacc atgctggccg gccactaccc     1320

cttccaggac tcggagcctg tcctgctctt cggcaagatc cgccgcgggg cctacgcctt     1380

gcctgcaggc ctctcggccc ctgcccgctg tctggttcgc tgcctccttc gtcgggagcc     1440

agctgaacgg ctcacagcca caggcatcct cctgcacccc tggctgcgac aggacccgat     1500

gcccttagcc ccaacccgat cccatctctg ggaggctgcc caggtggtcc ctgatggact     1560

ggggctggac gaagccaggg aagaggaggg agacagagaa gtggttctgt atggctagga     1620

ccaccctact acacgctcag ctgccaacag tggattgagt ttgggggtag ctccaagcct     1680

tctcctgcct ctgaactgag ccaaaccttc agtgccttcc agaagggaga aaggcagaag     1740

cctgtgtgga gtgtgctgtg tacacatctg ctttgttcca cacacatgca gttcctgctt     1800

gggtgcttat caggtgccaa gccctgttct cggtgctggg agtacagcag tgagcaaagg     1860

agacaatatt ccctgctcac agagatgaca aactggcatc cttgagctga caacactttt     1920

ccatgaccat aggtcactgt ctacactggg tacactttgt accagtgtcg gcctccactg     1980

atgctggtgc tcaggcacct ctgtccaagg acaatccctt tcacaaacaa accagctgcc     2040

tttgtatctt gtaccttttc agagaaaggg aggtatccct gtgccaaagg ctccaggcct     2100

ctcccctgca actcaggacc caagcccagc tcactctggg aactgtgttc ccagcatctc     2160

tgtcctcttg attaagagat tctccttcca ggcctaagcc tgggatttgg gccagagata     2220

agaatccaaa ctatgaggct agttcttgtc taactcaaga ctgttctgga atgagggtcc     2280

aggcctgtca accatggggc ttctgacctg agcaccaagg ttgagggaca ggattaggca     2340

gggtctgtcc tgtggccacc tggaaagtcc caggtgggac tcttctgggg acacttgggg     2400

tccacaatcc caggtccata ctctaggttt tggataccat gagtatgtat gtttacctgt     2460

gcctaataaa ggagaattat gaaataaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa                                 2554


<210>  2549
<211>  5056
<212>  DNA
<213>  homo sapiens

<400>  2549
actcggctgg gagaatccgc gccagggaat ccagctctcc ggactcagct gcaaacaaaa       60

agcgccgggt cttgctccct cctcccgccc gccgacgcgc acccggagaa acagttttat      120

acagaaatgc aacaagtagt acccggggtc tgcagagcgc cccgcgccgc ctgacttggc      180

cgggcgaagc ccgcctgcag agacccgggc cggcctccgg acaaaggacg gaggaggggc      240

tggacggcgc tgcgaagtcc gaaagaggcc atttagcgac tctggccagg ctaaggggaa      300

tgcagaggag acacagagcc ggcgggccaa gaggacgatc cggccgctgc acgcagggcg      360

ggaggcgatg gaggctgccc gcgccttgcg cctcctgctc gtggtgtgcg gctgcctcgc      420

gctcccgccg ctggccgagc ccgtgtgccc ggagcgctgc gactgccagc atccccagca      480

tctcctgtgc accaacaggg ggctccgcgt agtgcccaag accagctcgc tgccgagccc      540

ccacgacgtg ctcacctaca gcctcggcgg caacttcata accaacatca cggccttcga      600

cttccaccgt ctggggcagc tcagacggct ggacctgcag tacaaccaga tccgctctct      660

gcaccccaag accttcgaga agctctcgcg gctggaagag ctgtacctgg ggaacaacct      720

cttgcaggcg ctcgccccgg gcacgctggc cccgctgcgc aagctgcgca tcctctacgc      780

caacgggaac gagatcagcc gcctaagccg cggctccttc gagggcctgg agagtctagt      840

caagctgcgg ctggacggga acgccctggg ggcgctgccg gacgcggtct tcgctccctt      900

gggcaacctg ctctacctac atctggagtc caaccggatc cgctttctgg gcaagaacgc      960

cttcgcccag ctaggcaagc tgcgcttcct caacctctct gccaacgagc tacagccctc     1020

cctgcgccac gcggccacct tcgcaccgct gcgctccctc tcctccctca tcctctcggc     1080

caacaacctg cagcacctcg ggccgcgcat cttccagcac ctgccacgtc tcggcctgct     1140

ctcgctcagg ggcaaccagc tcacgcacct cgcgcctgag gccttttggg gcttggaggc     1200

cctgcgcgag ctgcgcctgg agggtaatcg gctgagccag ctgccaactg cgctgctgga     1260

gcctctgcac agcctggagg cgctggacct gagcggcaat gagctgtccg ccctgcaccc     1320

ggccaccttc ggccacctgg gccggctgcg cgagctcagc ctgcgcaaca acgcgctcag     1380

cgccctatcc ggggacatct tcgccgccag cccagccctt tatcggctgg atctagacgg     1440

caacggctgg acctgcgact gccggctgcg aggcctgaag cgctggatgg gcgactggca     1500

ctcgcagggc cggctcctca ctgtcttcgt gcagtgtcgc caccccccgg ccctgcgagg     1560

caaatacctg gattacctgg atgaccagca gctgcaaaat ggatcctgcg cggatccctc     1620

gccctcagct tccctgaccg ctgaccgcag gcggcagccc ctacccacgg ccgcagggga     1680

ggagatgacg ccacctgcag gtctcgcgga ggagctgccg ccgcagccgc agctccagca     1740

gcaggggcga tttctagctg gggtggcctg ggatggggcc gccagggagc tggtaggcaa     1800

ccgcagcgcc ctaaggctga gtcggcgggg cccgggcctc cagcagccca gcccctccgt     1860

cgctgccgcc gcgggcccgg ctccacagtc cctagacctg cacaagaagc cccagcgggg     1920

ccgtccgact cgggcagatc ccgccctcgc ggagcccacc ccaacggcct ctcctggctc     1980

tgcgccatcg cccgccggcg acccctggca gcgcgcgacg aagcatcgtc tgggcacgga     2040

gcaccaggag cgtgccgccc agtccgacgg tggggccggg ctgccgccgc tggtgtccga     2100

cccatgcgac ttcaacaagt tcattctgtg caacctgacg gtggaggcgg tgggcgcaga     2160

cagcgcctcg gtgcgctggg ccgtgcgcga gcaccgcagt ccccggccgc tgggcggcgc     2220

gcgcttccgc ctgctctttg accgctttgg ccagcagccc aagttccacc gcttcgtcta     2280

cctgcctgag agcagcgact cggccacgct gcgcgagctg cgcggggaca ccccctacct     2340

ggtgtgcgtg gagggcgtgc ttgggggccg tgtctgccct gtggctcccc gggaccactg     2400

cgcggggctg gtcaccctac cggaggccgg gagccggggc ggcgtcgact accagctgct     2460

gaccttggcc ctgctgacgg tcaacgcgct gctggtgctc ctggccttgg cggcctgggc     2520

gtctcgctgg ctgcgtagga aactgcgggc taggcggaag ggcggggccc cggtccacgt     2580

tcggcacatg tactccaccc gacggcccct gcgctccatg ggcaccggcg tgtccgccga     2640

cttctcggga ttccagtcgc accggccacg caccaccgtg tgcgcgctca gtgaggcgga     2700

cctcatcgaa ttcccctgcg accgcttcat ggacagtgcg ggcggcggcg cgggcggcag     2760

cctgagacgg gaggaccgtc tcctgcagcg atttgccgac taggtccagg gcatatagag     2820

accatctcat tggccctaag gagccgcctc tccgtgaggc ccaccagccc acctcagggg     2880

aagtgccgtt ttgtgcactt gccagagagg ccggtgggga cagagggcca attcgggcac     2940

catcccccaa ttcccaatac tcgagaagta aatggatggt acttggtggt cagagccaga     3000

gtaggggaca aatggatggt gggatgctga ggtcggaggc ttcgcttgga ggctttgaca     3060

cagctatgcg aatggctttt gtagcactgc aatgcagaag ccaggctttg ggggtagaaa     3120

gggggtgctt gtgcccccaa catggccaga aatatttggg tgcatgcttt ttgtttgctc     3180

agtgtcaaac agagaagttt tgtttctatt taaggaagga acttattacc attacaaagg     3240

aggcttggcc agggactcca ctggtttggt gatctctgcc aagaaggggg atgtaaacag     3300

gtggtaaagt ttaacatacc cgccaaggaa ctcgtttatg ttggctgata gagcattcag     3360

gataccttaa agtttaataa gagacgcatt tttttttttc aaaaatgtga aaagctctga     3420

catttaacga actgaccaat agactcaagg actgttttag ttggactggg ccattttatt     3480

atgttccttt taatattaac agtacaagag cgcttgctga cttcgaggat aactaagatt     3540

acatactttc tcaggagaag gctgcatgca agacttctct gtcagggttg ctcctgtggc     3600

ttttttaatt ttattttttt aaacctatat atggaaaagg aaatttcaat gccagatttg     3660

ataaaagaat gtgatgtata tgtagctgat gacccactgg ggaacaccag tgttccagtt     3720

cacttaccac atctgtgaca gtgtgtttag attggaataa atgtgatgca ttacttctta     3780

tgtttttatc agtgacatgg ttgactgtgc cctaattctc ttgagttgca gttaagcaat     3840

gaaggttatt tcctaatagg gaagcaaaag gtgattgtca attgatagtt taatgtttga     3900

ccacattagt gtctttatat gaaatagtag aggggaagaa attatagaaa acaaatgtga     3960

aaaaaataca ccagtgggta tctgttctac taaaaccaga agattgttat gagtacttaa     4020

acctcactgt gaaataatga tatattttgc aattaatccc tccccaactg agtgtcttac     4080

tgtgttatta aatcttatct tttagttaat agttgcagta tttcttttaa atgtttttgt     4140

tttaaactta ggggtaggat cctttatttg ttcagttgtt tccaactatt tgggatactt     4200

tcattccctg ctatttatga agtacatgtt tatcactaag tgtagtggtt tggtttacat     4260

taataatttt atgtgtggtc taaaaatgca gtcactaaga gaatgtacac tgtggttatg     4320

gtcacagtgg ttatggattt attggcagtg gagtaccatg gaggtcactg caatggtgct     4380

aaggctgaca gtggaatctt ctgtttaggg ccttaagccc ctgagggtcc tggtgactca     4440

gggaatccat cacagccccg ggtctttcac cccagttcac tccttttatg tttggcctag     4500

attgacccat gcctgccctc ttctcaacag ctgagtaggg aaccagccat ctgaatgagc     4560

tgatcgttgt ttatgttcaa atgagtaaat gtccagacca cttaaaacta cagctgcttt     4620

tctggcagtc tcgtctgcgg ggccaaaact taataaacca caggaaatag actgtcattc     4680

ttagtttgct gccagggctt attttagatt gagagcatac tggtacatga gagcagtagt     4740

gttgtttgct cttattttca accagggagc tatctggcac cttttgtgct cctggctttt     4800

ttcaatcata gcactattgc atctcctagc tatttctttt gcccagcagg gtaatattga     4860

gtcccattgc aagtatggac aaggcctctg gttctcctca ccacccacct tttcagccat     4920

agaacatcac tgaaaatgcc taatgcctgg atctgtgttc tactttagtt tcactgggaa     4980

gtctttcagt gggagatgaa taaatgttat acattgttat gtccagttat gtcaataaac     5040

ccactaatag agataa                                                     5056


<210>  2550
<211>  5245
<212>  DNA
<213>  homo sapiens

<400>  2550
ggctgcatcg acagcttgca acactcggca tcttttctgg aggcgcctcc ttcagcagcc       60

gcagatggca tccggctgcg ggctcggggc tcgcaattga ttctccccct tgcccacctc      120

gagtccacgg acgcacctct cccttcccct cctcccttcg cgcttctggg tctgagccca      180

gctcgcgacc gccgggcaga ggatcagtcg cggcggccga ggctgagcag cagcgctctc      240

gctccctgac ctggggagaa gcgcccaccc gggagagctg atccccggct gcctccagcg      300

ccccccacct tttgcactcc aagccggggg ctccagagac cccgctcccc aggcgccact      360

atgctggacc cttcgtccag cgaagaagaa tcggatgaga tcgtggagga ggagagcggc      420

aaggaggtgc tcggctcggc cccgtccggc gcgcgcctgt ctcccagccg taccagcgag      480

ggctcggccg gcagcgccgg gctggggggc ggcggcgccg gcgccggagc cggggtgggt      540

gcaggcggcg gcgggggcag cggcgcgagc agcggcggcg gggccggggg gctgcaaccc      600

agcagccgcg ctggcggcgg ccggccctcc agccccagcc cgtcggtggt gagcgagaag      660

gagaaggaag agttggagcg gctgcagaaa gaggaggagg agaggaagaa gaggctgcag      720

ctgtatgtgt tcgtgatgcg ctgcatcgcc taccccttta atgccaagca gcccaccgac      780

atggctcgcc ggcagcagaa gatcagcaaa cagcagctgc agacagtcaa ggaccggttt      840

caggctttcc tcaatgggga aacccagatc atggctgacg aagccttcat gaacgctgtg      900

cagagttact atgaggtgtt cctgaagagc gaccgtgtgg cccgcatggt tcagagtgga      960

ggctgttccg ccaacgactc ccgggaggtc ttcaagaagc acattgagaa gagagtgcgc     1020

agcctgcctg agattgacgg cctcagcaag gagactgtgc tgagctcctg gatggccaaa     1080

tttgatgcca tctaccgtgg agaagaggac ccgcggaagc agcaggcccg gatgacagcc     1140

agcgcagcct ccgagctgat tctgagcaag gagcaactct atgagatgtt ccagaacatt     1200

cttgggatca agaagttcga acatcagctc ctttacaatg cctgccagct ggacaatcca     1260

gatgagcaag cagcccagat cagacgagag ctggatggac gtctacaaat ggcagaccaa     1320

atagccaggg aacgcaaatt tcccaagttt gtatccaaag aaatggaaaa catgtacatt     1380

gaggagctga agtcatctgt caacctgctc atggccaact tggagagcat gccggtatcc     1440

aaaggcgggg agttcaagct ccagaaactc aaacgcagcc acaatgcttc catcatcgac     1500

atgggcgagg agagtgagaa ccagctctcc aagtcagatg tcgtgctgtc tttctcattg     1560

gaggtggtaa ttatggaagt ccaaggcctc aaatctttgg ctccaaatcg catcgtatat     1620

tgcacaatgg aggtggaagg aggagagaaa ctacagactg atcaggccga ggcttctaaa     1680

ccaacctggg gcacccaggg tgacttctcc acaacccatg cactgccagc tgtgaaggtg     1740

aagctgttca cagagagcac aggcgtcctg gcgttggagg acaaggagct tgggcgggtt     1800

attctccatc ccaccccgaa cagccccaaa cagtcagagt ggcacaaaat gacagtctcc     1860

aaaaactgcc ccgaccaaga tctcaaaatc aaacttgctg tccgaatgga taagcctcaa     1920

aacatgaagc attctgggta tttatgggcc atcggtaaga atgtctggaa gagatggaag     1980

aaaaggtttt ttgtattggt gcaggtcagt cagtacacgt ttgccatgtg cagttatcgg     2040

gagaagaaag cggagcctca ggaacttcta caattggatg gctacactgt ggattacacc     2100

gacccccagc caggtttgga gggtggccga gccttcttca atgctgtcaa ggagggagac     2160

accgtgatat ttgccagtga cgatgaacaa gaccgcatcc tgtgggtcca ggccatgtat     2220

cgggccacgg ggcagtcaca caagcctgtg cccccgaccc aagtccagaa actcaacgcc     2280

aagggaggaa atgtacctca gctggatgcc cctatctctc aattttacgc agatagagct     2340

caaaaacatg gcatggatga atttatctct tccaacccct gtaactttga ccacgcttcc     2400

ctctttgaga tgggctggtt cagtcctggc caggtgtttg tactagacga gtattgcgcc     2460

cgaaatggag tccgggggtg tcaccgacat ctctgctacc tcagagactt gcttgaacgg     2520

gcagaaaatg gcgccatgat cgaccccacc cttcttcact acagctttgc cttctgtgca     2580

tcccatgtcc atgggaacag gcctgatgga attggaactg tgactgttga agaaaaggaa     2640

cgttttgaag aaatcaaaga gaggctccga gttctgctag aaaatcagat tacacatttt     2700

aggtattgct ttccatttgg tcgacctgaa ggtgctttga aagctactct ctcactcttg     2760

gaaagggttt tgatgaaaga tattgttacc ccagtgccac aagaggaggt aaaaacagtt     2820

atccgtaaat gtctggaaca ggctgcgtta gtcaactatt ctcggctctc agagtatgcc     2880

aaaatcgaag aaaatgtagg ccggttaatc actcctgcca aaaagcttga agatacaata     2940

cgtcttgctg aactagtcat tgaagttctt cagcaaaatg aggagcacca cgcagaggcc     3000

tttgcgtggt ggtcagattt aatggtggag catgcggaga cgttcctgtc actctttgca     3060

gtagacatgg atgcagcctt agaggtgcaa cctccagaca catgggacag ttttccacta     3120

tttcagctgc tgaatgattt tctccgtact gactataatt tgtgcaatgg aaaatttcac     3180

aaacacctgc aagacctgtt tgccccactt gttgttagat atgtggatct gatggagtcc     3240

tcaattgcac aatccattca caggggcttt gagcgggagt catgggaacc agtcaataat     3300

gggtcaggca cctcagaaga tctgttttgg aaacttgacg cccttcagac cttcattcgg     3360

gacctgcact ggcctgaaga agagtttgga aagcacctgg aacaacggct gaagttgatg     3420

gcaagtgaca tgatcgaatc ttgtgtcaaa agaaccagga ttgcatttga agttaagctg     3480

caaaaaacca gtcgatcaac agattttcga gtcccacagt caatatgcac catgtttaat     3540

gttatggttg atgccaaagc tcaatcaaca aaactttgca gcatggaaat gggccaagag     3600

catcaatacc attcaaaaat agacgaacta attgaagaaa ctgttaaaga aatgataaca     3660

ctcttggttg caaagttcgt tactatcttg gaaggagtgc tggcaaaatt atccagatat     3720

gacgaaggga ctttgttttc ttcttttctg tcatttaccg tgaaggcagc ttccaaatat     3780

gtggatgtac ctaaacccgg gatggacgtg gccgacgcct acgtgacttt cgtccgccat     3840

tctcaggatg tcctgcgtga taaggtcaat gaggagatgt acatagaaag gttatttgat     3900

caatggtaca acagctccat gaacgtgatc tgcacctggt tgacggaccg gatggactta     3960

cagcttcata tttatcagtt gaaaacacta attaggatgg taaagaaaac ctacagagat     4020

ttccgattgc aaggggtcct ggactccacc ttaaacagca agacctatga aacgatccgg     4080

aaccgtctca ctgtggagga agccacagca tcagtgagtg aaggtggggg actgcagggc     4140

atcagcatga aggacagcga tgaggaagac gaagaagacg attagaccat ttggtcctag     4200

agtctgctgg gacagagtcc tgtaatcagt gcatgtcctt agtctgttag ttaaacccat     4260

taggaatttt ctgtcaacta ccatgcccat gagatgttta tcaatacaac tgccatttta     4320

gctatgtggt accaagatta gcaaatgacc ttcatatcca ctgatttcct gatgtccatg     4380

tctatatgtt tacaagcaat atggagcacc attctttaaa tactgttcat ggagaataca     4440

tagtctaacc actaggcgtg tccctgttat cagcaaagat caatgatgct tcattcatgt     4500

actatgtatg cattggtggt aaatggatgt gagggcaagt acatcaagta cattcactct     4560

gtttcacgta tgtggatgcc agttaattaa atgagtacgt aaataaatta attaaaacac     4620

atagatctgc tttgtgtttt tatttttatt ttttgaaaaa caaaaggcaa gtctccaaca     4680

attaactttt gatgctttct gttcccctaa aaccaaaaaa tgaacccctt gtgtcgttgt     4740

taacccatcc tttcatttac tcatataatt agccaaaaaa aaaaggatgg ctacatacca     4800

atggattgat tctcttaatt gccacggcaa gggggcgatc ctatcatgac ttaacatcaa     4860

gcgcgcagtt caaaactact gtcttctgtc aaagttttct cctcttaaat gttattttgc     4920

ttttacgtct caactgtgta tgtaaaaaaa atgaatattt aaattacaac cctagactaa     4980

aaatgtgttt ataataagat gtggatattt ccttcagtag attgtaacca taatttaaat     5040

tattttgttc cacactgttt tttatatctg tcatgtacat tgcattttga tctgtaactg     5100

cacaaccctg gggtttgctg cagagctatt tctttccatg taaagtagtg gatccatctt     5160

gcttttgcct tatataaagc ctacagttat ggaagtgtgg aaaactgtgg cttctcaata     5220

aatattcaga tgtcctaaga atata                                           5245


<210>  2551
<211>  5365
<212>  DNA
<213>  homo sapiens

<400>  2551
ggctgcatcg acagcttgca acactcggca tcttttctgg aggcgcctcc ttcagcagcc       60

gcagatggca tccggctgcg ggctcggggc tcgcaattga ttctccccct tgcccacctc      120

gagtccacgg acgcacctct cccttcccct cctcccttcg cgcttctggg tctgagccca      180

gctcgcgacc gccgggcaga ggatcagtcg cggcggccga ggctgagcag cagcgctctc      240

gctccctgac ctggggagaa gcgcccaccc gggagagctg atccccggct gcctccagcg      300

ccccccacct tttgcactcc aagccggggg ctccagagac cccgctcccc aggcgccact      360

atgctggacc cttcgtccag cgaagaagaa tcggatgaga tcgtggagga ggagagcggc      420

aaggaggtgc tcggctcggc cccgtccggc gcgcgcctgt ctcccagccg taccagcgag      480

ggctcggccg gcagcgccgg gctggggggc ggcggcgccg gcgccggagc cggggtgggt      540

gcaggcggcg gcgggggcag cggcgcgagc agcggcggcg gggccggggg gctgcaaccc      600

agcagccgcg ctggcggcgg ccggccctcc agccccagcc cgtcggtggt gagcgagaag      660

gagaaggaag agttggagcg gctgcagaaa gaggaggagg agaggaagaa gaggctgcag      720

ctgtatgtgt tcgtgatgcg ctgcatcgcc taccccttta atgccaagca gcccaccgac      780

atggctcgcc ggcagcagaa gatcagcaaa cagcagctgc agacagtcaa ggaccggttt      840

caggctttcc tcaatgggga aacccagatc atggctgacg aagccttcat gaacgctgtg      900

cagagttact atgaggtgtt cctgaagagc gaccgtgtgg cccgcatggt tcagagtgga      960

ggctgttccg ccaacgactc ccgggaggtc ttcaagaagc acattgagaa gagagtgcgc     1020

agcctgcctg agattgacgg cctcagcaag gagactgtgc tgagctcctg gatggccaaa     1080

tttgatgcca tctaccgtgg agaagaggac ccgcggaagc agcaggcccg gatgacagcc     1140

agcgcagcct ccgagctgat tctgagcaag gagcaactct atgagatgtt ccagaacatt     1200

cttgggatca agaagttcga acatcagctc ctttacaatg cctgccagct ggacaatcca     1260

gatgagcaag cagcccagat cagacgagag ctggatggac gtctacaaat ggcagaccaa     1320

atagccaggg aacgcaaatt tcccaagttt gtatccaaag aaatggaaaa catgtacatt     1380

gaggagctga agtcatctgt caacctgctc atggccaact tggagagcat gccggtatcc     1440

aaaggcgggg agttcaagct ccagaaactc aaacgcagcc acaatgcttc catcatcgac     1500

atgggcgagg agagtgagaa ccagctctcc aagtcagatg tcgtgctgtc tttctcattg     1560

gaggtggtaa ttatggaagt ccaaggcctc aaatctttgg ctccaaatcg catcgtatat     1620

tgcacaatgg aggtggaagg aggagagaaa ctacagactg atcaggccga ggcttctaaa     1680

ccaacctggg gcacccaggg tgacttctcc acaacccatg cactgccagc tgtgaaggtg     1740

aagctgttca cagagagcac aggcgtcctg gcgttggagg acaaggagct tgggcgggtt     1800

attctccatc ccaccccgaa cagccccaaa cagtcagagt ggcacaaaat gacagtctcc     1860

aaaaactgcc ccgaccaaga tctcaaaatc aaacttgctg tccgaatgga taagcctcaa     1920

aacatgaagc attctgggta tttatgggcc atcggtaaga atgtctggaa gagatggaag     1980

aaaaggtttt ttgtattggt gcaggtcagt cagtacacgt ttgccatgtg cagttatcgg     2040

gagaagaaag cggagcctca ggaacttcta caattggatg gctacactgt ggattacacc     2100

gacccccagc caggtttgga gggtggccga gccttcttca atgctgtcaa ggagggagac     2160

accgtgatat ttgccagtga cgatgaacaa gaccgcatcc tgtgggtcca ggccatgtat     2220

cgggccacgg ggcagtcaca caagcctgtg cccccgaccc aagtccagaa actcaacgcc     2280

aagggaggaa atgtacctca gctggatgcc cctatctctc aattttacgc agatagagct     2340

caaaaacatg gcatggatga atttatctct tccaacccct gtaactttga ccacgcttcc     2400

ctctttgaga tggtacaacg ccttactttg gatcacagac ttaatgattc ctattcttgc     2460

ctgggctggt tcagtcctgg ccaggtgttt gtactagacg agtattgcgc ccgaaatgga     2520

gtccgggggt gtcaccgaca tctctgctac ctcagagact tgcttgaacg ggcagaaaat     2580

ggcgccatga tcgaccccac ccttcttcac tacagctttg ccttctgtgc atcccatgtc     2640

catgggaaca ggcctgatgg aattggaact gtgactgttg aagaaaagga acgttttgaa     2700

gaaatcaaag agaggctccg agttctgcta gaaaatcaga ttacacattt taggtattgc     2760

tttccatttg gtcgacctga aggtgctttg aaagctactc tctcactctt ggaaagggtt     2820

ttgatgaaag atattgttac cccagtgcca caagaggagg taaaaacagt tatccgtaaa     2880

tgtctggaac aggctgcgtt agtcaactat tctcggctct cagagtatgc caaaatcgaa     2940

gggaaaaaga gagaaatgta tgagcatcct gtcttctgct tggcctccca agtgatggat     3000

ttaaccattc aaaatgtagg ccggttaatc actcctgcca aaaagcttga agatacaata     3060

cgtcttgctg aactagtcat tgaagttctt cagcaaaatg aggagcacca cgcagaggcc     3120

tttgcgtggt ggtcagattt aatggtggag catgcggaga cgttcctgtc actctttgca     3180

gtagacatgg atgcagcctt agaggtgcaa cctccagaca catgggacag ttttccacta     3240

tttcagctgc tgaatgattt tctccgtact gactataatt tgtgcaatgg aaaatttcac     3300

aaacacctgc aagacctgtt tgccccactt gttgttagat atgtggatct gatggagtcc     3360

tcaattgcac aatccattca caggggcttt gagcgggagt catgggaacc agtcaataat     3420

gggtcaggca cctcagaaga tctgttttgg aaacttgacg cccttcagac cttcattcgg     3480

gacctgcact ggcctgaaga agagtttgga aagcacctgg aacaacggct gaagttgatg     3540

gcaagtgaca tgatcgaatc ttgtgtcaaa agaaccagga ttgcatttga agttaagctg     3600

caaaaaacca gtcgatcaac agattttcga gtcccacagt caatatgcac catgtttaat     3660

gttatggttg atgccaaagc tcaatcaaca aaactttgca gcatggaaat gggccaagag     3720

catcaatacc attcaaaaat agacgaacta attgaagaaa ctgttaaaga aatgataaca     3780

ctcttggttg caaagttcgt tactatcttg gaaggagtgc tggcaaaatt atccagatat     3840

gacgaaggga ctttgttttc ttcttttctg tcatttaccg tgaaggcagc ttccaaatat     3900

gtggatgtac ctaaacccgg gatggacgtg gccgacgcct acgtgacttt cgtccgccat     3960

tctcaggatg tcctgcgtga taaggtcaat gaggagatgt acatagaaag gttatttgat     4020

caatggtaca acagctccat gaacgtgatc tgcacctggt tgacggaccg gatggactta     4080

cagcttcata tttatcagtt gaaaacacta attaggatgg taaagaaaac ctacagagat     4140

ttccgattgc aaggggtcct ggactccacc ttaaacagca agacctatga aacgatccgg     4200

aaccgtctca ctgtggagga agccacagca tcagtgagtg aaggtggggg actgcagggc     4260

atcagcatga aggacagcga tgaggaagac gaagaagacg attagaccat ttggtcctag     4320

agtctgctgg gacagagtcc tgtaatcagt gcatgtcctt agtctgttag ttaaacccat     4380

taggaatttt ctgtcaacta ccatgcccat gagatgttta tcaatacaac tgccatttta     4440

gctatgtggt accaagatta gcaaatgacc ttcatatcca ctgatttcct gatgtccatg     4500

tctatatgtt tacaagcaat atggagcacc attctttaaa tactgttcat ggagaataca     4560

tagtctaacc actaggcgtg tccctgttat cagcaaagat caatgatgct tcattcatgt     4620

actatgtatg cattggtggt aaatggatgt gagggcaagt acatcaagta cattcactct     4680

gtttcacgta tgtggatgcc agttaattaa atgagtacgt aaataaatta attaaaacac     4740

atagatctgc tttgtgtttt tatttttatt ttttgaaaaa caaaaggcaa gtctccaaca     4800

attaactttt gatgctttct gttcccctaa aaccaaaaaa tgaacccctt gtgtcgttgt     4860

taacccatcc tttcatttac tcatataatt agccaaaaaa aaaaggatgg ctacatacca     4920

atggattgat tctcttaatt gccacggcaa gggggcgatc ctatcatgac ttaacatcaa     4980

gcgcgcagtt caaaactact gtcttctgtc aaagttttct cctcttaaat gttattttgc     5040

ttttacgtct caactgtgta tgtaaaaaaa atgaatattt aaattacaac cctagactaa     5100

aaatgtgttt ataataagat gtggatattt ccttcagtag attgtaacca taatttaaat     5160

tattttgttc cacactgttt tttatatctg tcatgtacat tgcattttga tctgtaactg     5220

cacaaccctg gggtttgctg cagagctatt tctttccatg taaagtagtg gatccatctt     5280

gcttttgcct tatataaagc ctacagttat ggaagtgtgg aaaactgtgg cttctcaata     5340

aatattcaga tgtcctaaga atata                                           5365


<210>  2552
<211>  4402
<212>  DNA
<213>  homo sapiens

<400>  2552
cgtaacccag gcagctgggg agcctgggct gtggccctag gagggggcgc ggcggcgggc       60

tctctccttt tgttgttgtt tcctcagcct ggggagctga aggggagacg cgtctgggtg      120

gggctgctcg gagcccgggc ctggtggccc ctggggctcc cgggcgggca gggtagggca      180

gagtagagcg ggcttcaaca tgatggcggc cgaggccggc agtgaggagg gcggcccggt      240

aacagccgga gctggaggag gcggcgcggc agcgggctcc agtgcctatc ccgcagtgtg      300

tcgggtgaag atacccgcgg ccctgcctgt ggcagccgcc ccctatcctg ggctggtgga      360

gaccggagtg gctggaactc tgggtggcgg agccgctttg gggtcagagt tcctaggagc      420

cgggtctgtg gcaggggcac tggggggagc tggactgaca gggggaggta ctgctgctgg      480

cgtagctggt gctgctgctg gcgtggccgg tgctgctgtt gctggaccta gtggagacat      540

ggctctcacc aaactgccca cttcgttgct tgctgagact ctcgggccag gcggcggttt      600

tccccctctg ccccctcccc cttacctgcc ccctttgggg gcgggcctcg ggacagtgga      660

cgaaggtgac tctctggatg gaccagaata cgaggaggaa gaggtggcca taccgttgac      720

cgctcctcca actaaccagt ggtatcacgg aaaacttgac agaacgatag cagaagaacg      780

cctcaggcag gcagggaagt ctggcagtta tcttataaga gagagtgatc ggaggccagg      840

gtcctttgta ctttcatttc ttagccagat gaatgttgtc aaccatttta ggattattgc      900

tatgtgtgga gattactaca ttggtggaag acgtttttct tcactgtcag acctaatagg      960

ttattacagt catgtttctt gtttgcttaa aggagaaaaa ttactttacc cagttgcacc     1020

accagagcca gtagaagata gaaggcgtgt acgagctatt ctaccttaca caaaagtacc     1080

agacactgat gaaataagtt tcttaaaagg agatatgttc attgttcata atgaattaga     1140

agatggatgg atgtgggtta caaatttaag aacagatgaa caaggcctta ttgttgaaga     1200

cctagtagaa gaggtgggcc gggaagaaga tccacatgaa ggaaaaatat ggttccatgg     1260

gaagatttcc aaacaggaag cttataattt actaatgaca gttggtcaag tctgcagttt     1320

tcttgtgagg ccctcagata atactcctgg cgattattca ctttatttcc ggaccaatga     1380

aaatattcag cgatttaaaa tatgtccaac gccaaacaat cagtttatga tgggaggccg     1440

gtattataac agcattgggg acatcataga tcactatcga aaagaacaga ttgttgaagg     1500

atattatctt aaggaacctg taccaatgca ggatcaagaa caagtactca atgacacagt     1560

ggatggcaag gaaatctata ataccatccg tcgtaaaaca aaggatgcct tttataaaaa     1620

cattgttaag aaaggttatc ttctgaaaaa gggcaaagga aaacgttgga aaaatttata     1680

ttttatctta gagggtagtg atgcccaact tatttatttt gaaagcgaaa aacgagctac     1740

caaaccaaaa ggattaatag atctcagtgt atgttctgtc tatgtcgttc atgatagtct     1800

ctttggcagg ccaaactgtt ttcagatagt agttcagcac tttagtgaag aacattacat     1860

cttttacttt gcaggagaaa ctccagaaca agcagaggat tggatgaaag gtctgcaggc     1920

attttgcaat ttacggaaaa gtagtccagg gacatccaat aaacgccttc gtcaggtcag     1980

cagccttgtt ttacatattg aagaagccca taaactccca gtaaaacatt ttactaatcc     2040

atattgtaac atctacctga atagtgtcca agtagcaaaa actcatgcaa gggaagggca     2100

aaacccagta tggtcagaag agtttgtctt tgatgatctt cctcctgaca tcaatagatt     2160

tgaaataact cttagtaata aaacaaagaa aagcaaagat cctgatatct tatttatgcg     2220

ctgccagttg agccgattac agaaagggca tgccacagat gaatggtttc tgctcagctc     2280

ccatatacca ttaaaaggta ttgaaccagg gtccctgcgt gttcgagcac gatactctat     2340

ggaaaaaatc atgccagaag aagagtacag tgaatttaaa gagcttatac tgcaaaagga     2400

acttcatgta gtctatgctt tatcacatgt atgtggacaa gaccgaacac tactggccag     2460

catcctactg aggatttttc ttcacgaaaa gcttgaatcg ttgttgttat gcacactaaa     2520

tgacagagaa ataagcatgg aagatgaagc cactacccta tttcgagcca caacacttgc     2580

aagcaccttg atggagcagt atatgaaagc cactgctaca cagtttgttc atcatgcttt     2640

gaaagactct attttaaaga taatggaaag caagcagtct tgtgagttaa gtccatcaaa     2700

gttagaaaaa aatgaagatg tgaacactaa tttaacacac ctattgaaca tactttcaga     2760

gcttgtggag aaaatattca tggcttcaga aatacttcca ccgacattga gatatattta     2820

tgggtgttta cagaaatctg ttcagcataa gtggcctaca aataccacca tgagaacaag     2880

agttgttagt ggttttgttt ttcttcgact catctgtcct gccatcctga atccacggat     2940

gttcaatatc atctcagatt ctccatctcc tattgctgca agaacactga tattagtggc     3000

taaatctgtg cagaacttag caaatcttgt ggaatttgga gctaaggagc cctacatgga     3060

aggtgtcaat ccattcatca aaagcaacaa acatcgtatg atcatgtttt tagatgaact     3120

tgggaatgta cctgaacttc cggacactac agagcattct agaacggacc tgtcccgtga     3180

tttagcagca ttgcatgaga tttgcgtggc tcattcagat gaacttcgaa cgctcagtaa     3240

tgagcgtggt gcacagcagc acgtattgaa aaagcttctg gctataacag aactgcttca     3300

acaaaaacaa aaccagtata caaaaaccaa tgatgtcagg tagcagcctt cgccccagtg     3360

ttctgcatgg attcagcatg tccaacatgg taattcactt cagtttaatg tctcctttgc     3420

tcttgccaaa aaatagcaca cttttccaca ttccagtgat gtgtgagcta tgcaaacaaa     3480

atccaagatt ctgctggtga ataactatgc cagcaacctt gtaagctatc tgtgcaggat     3540

atttgcacta tttccacatg gaatcaatct ttaacaacct ctgagccttg gtgtacagac     3600

cacctttcac aaaacgaaat gctatgactg tatcttgata tctcgaactt tcaaaatata     3660

ttttcagtac acccagttgc caaagttttg ctgtctctta gagaaagaac tatgaaatca     3720

actgacaaga aacacattct tattgacaat tgtgtataac tggattgcag actgttctta     3780

ctgtaactac ttcctgatta ggaatatgac catttgactg ttcaatgatt atttgtattt     3840

acagtttcca gagtttgtca ttataatagg aacaatcttt gctgtatact tttaaaaaat     3900

actctgctat ttctcttgct ggaactgttg aaagaaaata tatagaatga tctattgctc     3960

atcagcttta ttttttaaac atacgactta ttttgttgaa attgtcaaag actgtattta     4020

gatctcataa tgctttgtta aatgtttaca agtaaatagt ttgaattcag taaatattat     4080

tggttgttgt attgatcaat gcatgttacc cattcaacca ttttatagac taccaatttc     4140

ttttatgtta actagaatgc ttttgttaaa agttatttgt tcattatttg tgctacccct     4200

ttgattatgc agacaacctc atcagctgcc taacttatcc atctttgaac ttctgactac     4260

ttgttgtatc tgctggatat ttagttcaac tgtatagttt tatttacttc tgtatgtgta     4320

tttttgtgaa gtattcacaa aggttaagtt aaaataaaac caagggatat cttgcataat     4380

tgattaaaaa aaaaaaaaaa aa                                              4402


<210>  2553
<211>  9145
<212>  DNA
<213>  homo sapiens

<400>  2553
gctctcatct caaagcgcgc cctcccttcc aggttgggtc ggacctgaac ccctaaaagc       60

ggaaccgcct cccgccctcg ccatcccgga gctgagtcgc cggcggcggt ggctgctgcc      120

agacccggag tttcctcttt cactggatgg agctgaactt tgggcggcca gagcagcaca      180

gctgtccggg gatcgctgca cgctgagctc cctcggcaag acccagcggc ggctcgggat      240

ttttttgggg gggcggggac cagccccgcg ccggcaccat gttcctggcg accctgtact      300

tcgcgctgcc gctcttggac ttgctcctgt cggccgaagt gagcggcgga gaccgcctgg      360

attgcgtgaa agccagtgat cagtgcctga aggagcagag ctgcagcacc aagtaccgca      420

cgctaaggca gtgcgtggcg ggcaaggaga ccaacttcag cctggcatcc ggcctggagg      480

ccaaggatga gtgccgcagc gccatggagg ccctgaagca gaagtcgctc tacaactgcc      540

gctgcaagcg gggtatgaag aaggagaaga actgcctgcg catttactgg agcatgtacc      600

agagcctgca gggaaatgat ctgctggagg attccccata tgaaccagtt aacagcagat      660

tgtcagatat attccgggtg gtcccattca tatcagtgga gcacattccc aaagggaaca      720

actgcctgga tgcagcgaag gcctgcaacc tcgacgacat ttgcaagaag tacaggtcgg      780

cgtacatcac cccgtgcacc accagcgtgt ccaacgatgt ctgcaaccgc cgcaagtgcc      840

acaaggccct ccggcagttc tttgacaagg tcccggccaa gcacagctac ggaatgctct      900

tctgctcctg ccgggacatc gcctgcacag agcggaggcg acagaccatc gtgcctgtgt      960

gctcctatga agagagggag aagcccaact gtttgaattt gcaggactcc tgcaagacga     1020

attacatctg cagatctcgc cttgcggatt tttttaccaa ctgccagcca gagtcaaggt     1080

ctgtcagcag ctgtctaaag gaaaactacg ctgactgcct cctcgcctac tcggggctta     1140

ttggcacagt catgaccccc aactacatag actccagtag cctcagtgtg gccccatggt     1200

gtgactgcag caacagtggg aacgacctag aagagtgctt gaaatttttg aatttcttca     1260

aggacaatac atgtcttaaa aatgcaattc aagcctttgg caatggctcc gatgtgaccg     1320

tgtggcagcc agccttccca gtacagacca ccactgccac taccaccact gccctccggg     1380

ttaagaacaa gcccctgggg ccagcagggt ctgagaatga aattcccact catgttttgc     1440

caccgtgtgc aaatttacag gcacagaagc tgaaatccaa tgtgtcgggc aatacacacc     1500

tctgtatttc caatggtaat tatgaaaaag aaggtctcgg tgcttccagc cacataacca     1560

caaaatcaat ggctgctcct ccaagctgtg gtctgagccc actgctggtc ctggtggtaa     1620

ccgctctgtc caccctatta tctttaacag aaacatcata gctgcattaa aaaaatacaa     1680

tatggacatg taaaaagaca aaaaccaagt tatctgtttc ctgttctctt gtatagctga     1740

aattccagtt taggagctca gttgagaaac agttccattc aactggaaca tttttttttt     1800

ttccttttaa gaaagcttct tgtgatcctt tggggcttct gtgaaaaacc tgatgcagtg     1860

ctccatccaa actcagaagg ctttgggata tgctgtattt taaagggaca gtttgtaact     1920

tgggctgtaa agcaaactgg ggctgtgttt tcgatgatga tgatgatcat gatgatgatc     1980

atcatgatca tgatgatgat catcatgatc atgatgatga ttttaacagt tttacttctg     2040

gcctttccta gctagagaag gagttaatat ttctaaggta actcccatat ctcctttaat     2100

gacattgatt tctaatgata taaatttcag cctacattga tgccaagctt ttttgccaca     2160

aagaagattc ttaccaagag tgggctttgt ggaaacagct ggtactgatg ttcaccttta     2220

tatatgtact agcattttcc acgctgatgt ttatgtactg taaacagttc tgcactcttg     2280

tacaaaagaa aaaacacctg tcacatccaa atatagtatc tgtcttttcg tcaaaataga     2340

gagtggggaa tgagtgtgcc gattcaatac ctcaatccct gaacgacact ctcctaatcc     2400

taagccttac ctgagtgaga agccctttac ctaacaaaag tccaatatag ctgaaatgtc     2460

gctctaatac tctttacaca tatgaggtta tatgtagaaa aaaattttac tactaaatga     2520

tttcaactat tggctttcta tattttgaaa gtaatgatat tgtctcattt ttttactgat     2580

ggtttaatac aaaatacaca gagcttcttt cccctcataa gtagtgttcg ctctgatatg     2640

aacttcacaa atacagctca tcaaaagcag actctgagaa gcctcgtgct gtagcagaaa     2700

gttctgcatc atgtgactgt ggacaggcag gaggaaacag aacagacaag cattgtcttt     2760

tgtcattgct cgaagtgcaa gcgtgcatac ctgtggaggg aactggtggc tgcttgtaaa     2820

tgttctgcag catctcttga cacacttgtc atgacacaat ccagtacctt ggttttcagg     2880

ttatctgaca aaggcagctt tgattgggac atggaggcat gggcaggttc tcctttcttt     2940

ggaaacacat ccatgctggg atgcacagtt cttttcctaa ggattgtgtt tactcctgac     3000

tgcaacgtct tggccactgt ttggagcagt ttggtctgaa ggtcattaag gatctgcttg     3060

catcttgttt catgtcctcc gtgacagact gcagaccatg ttagaagaga aggaaggttt     3120

gtggatcaag agggttgaca ttaggtttgg tgagatgagt tgcttggcac agatcagcag     3180

aacaggaccc tggtgataag gcatctggct ttgctaacca cttatcatct tccattattc     3240

tctttcttaa ctaagtagac ccgaaagtgc acttttgaag tctggtttag atggcgagat     3300

tccgaatcta caatgatcga gtactggtgg ccacttttct ccaacattaa gtaaagagga     3360

ggagattcca ccttcagaaa gtgctgggaa gcattggctt tcttcccaca ttggtagaag     3420

agatggagga ggaaaccagg gtgcacattt ctacagatcc cctttgcctg ctggtgtttg     3480

ccttgtaaga taagtcactg gggggaaggg gaaatctatg aaatccaaga taaaggcata     3540

gtctttcagc tctattggtg ttaaaagtat atttgtgtcc aaatgttaat caacacaaat     3600

gtacagtact cagtactgac ttttttcact tcaaaatgtt ttcaagggaa attcagcaga     3660

cacccaactg tatttaatta gtgaaaagat ctataaagac tcttactttg aataaacaca     3720

ttaagtaagt gtgtcaaaat atttggaatg ccagttatct atgagcgcat atctcttaca     3780

gagtgtattt tgttttcatt aaggtatctc tgtgtatcta cactggacta atttcatagg     3840

gatctgattc tatgtgatcc actgtagaaa gctactgatt acttctgcag taacagcagc     3900

tctaattagc atcagatgac caaagcggaa atgggagttt cagcgctaac aagggcagcc     3960

ttcattgaag aatgcatggg taggcaatat ataaattaca ttttgaaaag cctcatctgt     4020

caccaacaaa tatctcattt ttcttcagtg ataaaagcat attcaagtta ccagctcctc     4080

aatttgaaaa tcagttgctg attaaataaa tagggggaag catcttgttc agggacaaca     4140

cgttagagag attcttatca aagcaagcca agcaaggttt ccgccattca gtgtgatctt     4200

agtttgacac ggtgacccta aaacaccatc atttgcccca gaactggagc acaataagtt     4260

aaatcattta cctgtctcac ttcttcttgg cgtgcttaaa agcaaaaatg attcgctact     4320

tcctgtcctt cagtccgggc atttggggtg ccactgaaga caggggttat ctgctgaggt     4380

ttgggtgtct tgcaggaagt atctcattgc agttgatttt gatgaaacca aacagtaact     4440

agggtccatg cagaccgtga ctccctgatt acatctagcc atgccctact tatttcagag     4500

agaaagagag ggggaataaa ggcagtattg ccacactgat tagaagcaca ttcattccac     4560

tttgatgttg aatatttttg accgatacat gcttgagtat ctttttaata gagcacatga     4620

aggaagaagc acacaatata gagaaggaat tgagaatgcc aattacatat ttatttttcc     4680

atacctgatt tttttcaagt ctgtaataaa aaaagtataa gttgagatta acataggtta     4740

tttttcatga agtatagcaa acgatctaga atgtgatagg agtgtggttt ccatttcttt     4800

tttttttttt ttaacagact tttgtgctgt agtaagaatg tcttagaagt tgtgtcttcg     4860

agttcctcaa acaccggaca gggctccccc agagctgcct cagcctttga tttggtccat     4920

attcagacac ttcctgtctt gcatacactc tgaggatggg ccgcttctag ctgccgcccg     4980

tctccctctt gccttcttgt ctctaaatca gacactccca agcactccat ctgctatact     5040

aggagagtgg gagagccaaa gcattttgga gtccatgtaa agtgcctggg aaaagagatg     5100

taagagcagt gggagtttat ataattagcg aattcttttc tcagaattca gcggaaatgt     5160

atttctgttg ttattattta caaaattgtg gcctcagagg agctgtcttt tggaaaataa     5220

gttttcattc atgcagttag ttagacatgc acgatgtact tgaatcaata aactgtggac     5280

cagaaaaggg ctgcttaaat gaattcacgt gttctaattc tctttcgagg ctgttgatga     5340

cctcctggat tcataccccc atgatctgtc ttgctcttgc ctctgttctt tgataaagca     5400

catcagacta tgtgacaccc atcttttcaa gaacgaccta aaagcaatga caacaggcag     5460

gagagaatta ccactggcct gggcacagtg acagcagaag gcccacctga gcttggagag     5520

ttggcgagat aaggcaaaat caaggtgcaa cagtgggcca tgttccaagg gtgaatggat     5580

ctgagagtcc gctgatgttc cttactgatc agaacaggga ccttctaacg aaacagccag     5640

agttccttga atcaggcaga agttctttag agacaggaag ccagagctat tgataatatc     5700

cgaacgacag aggaaggaat ttcttattag aaattctaaa ataaaacaag tggggatttg     5760

gttggatacc cttagaagct acatttttct ctcatcccta agatagatat ctcaagtgta     5820

tatctgacac ctcttggctt tgacacggct ctgcttctca agtgaccatt tgttttaagt     5880

ctgttgtcta gaattctttg tgggggctgg acctctgaaa aagattctca ctgcagaggc     5940

tttaaatctg tgtttttttc cactccctcc gtcctgggat gtattcggta ggacatttca     6000

tttatatcag gatattggct gattcagctc tctttcatcg ttattattca ggcctccctc     6060

caccaccttg ttctttattg cctaagtatt gccctcccca attcttcatc gtaatagctc     6120

taaatttagt ttgacccaaa ttaatttttg ttccaacaga tatattttaa gacagagaag     6180

cctctctcag gagccagatg atctgaagat gatgctaatc cccaaatacg aagttcctcc     6240

agctaactct cctctgagct ccctcttctt agctttggga ttggggatgg tctcatcctt     6300

gccaggaatc cctttgttgc tcccagtgtc tctgatgagc ttctcctccc tcccagagac     6360

aatgcagggg tggttttcag cagaatgtgc cacctgcact tctgattgtt ctgagaccca     6420

gcccagaggg gtggagaagg cgcacaaacc ctattccaat aaactgcctg cagagaacca     6480

cagcctgcta atagtcgttg aggtctcagc cccctaaggt ctccaagctc atttgaccag     6540

cgcagctgcg acttcggctg tctgcctctg gcaggtgcca atatcagcat cttgtcccac     6600

tgccatgggg agttaatttt tgctccaggg cagctgccaa gcccagcacc ggcatcaata     6660

gaaggttttc tctgattttc ttctcttcct ctcaggctag gctttcttac caatccccaa     6720

ttttcttctg tagggcgcca ggagactggc cagagatctt tagactctta cttagtttga     6780

acatctcttg ctgctcacac ccaggcttct tcagcagaaa gcatgaccca tagtaggtac     6840

tcagaaactg gttgaatgaa aagccttgac atttaagggc tttattctgt catacggtag     6900

caagaactgg cctattggca tcgtattcct ggcattgagc tgtattgacc ctgaatgtgt     6960

cctcctgagg tttttgaggg tgacctagga gaaagggtct gaaaaagcac tgggatccaa     7020

gtgactttaa atctgcccgt ggcatttcct gctgagaggc gagaaactag catctctccc     7080

aacaggctca catccgccag gaaggacaga gcccaaaacg ggggtagact ttgtgggaaa     7140

ttcgccagtt agtccgctga gattttaatc tgcctcaagc acaggatgct gacaagaaag     7200

gtagaccact cccccgatcc cagacaaacc ccaggggtga caacttctcc atcagtatcc     7260

tgagaagcaa catcaaatgc ttaccaagtc agcacgttta ctgagtgagt actctgacgg     7320

aataaaccag catttggagc tgaacttgag aacacagggc cctctgacag cagcttaggg     7380

aaacacccat cccttccaga ttggcagaat ccttccattt catgtccttc ggagacgctg     7440

tattctcttt acaaatcatt catgaaactg agactcagtc tcccaggggt aagtcctggg     7500

ccacgtgcaa acaatggcaa atccagctct tccatgatag agaaggcaaa cacacccacc     7560

ttcatcctga gcctaaaagg ccacctctga gcacttgggc agccactcct ctgggcctca     7620

gagggccatg agcttggcca ggtaggcaca gcggcgggga agtcacagct gtcaggtacc     7680

ggccatggtg caggtgggaa taggagatgc cagagctgct ttagctgagg aaagcaaaca     7740

gtcagcagtg ctcaaaggag caaaacttcg aatgtgcaca ttgacccctg acacctgcaa     7800

gcataacaca gatcctaaga ctagagtgaa gtaggaagaa gaattagaaa atccagtgga     7860

tgtcctgagt atagggaacc agggccgttg aaaatcagta aaggttgatt acctggggcg     7920

agaccgggtg actgtggcag tgcaggtgaa ggtaccctgg accttctcag ttcgctggca     7980

cataaggctc cgccaataaa gcgtggttct ctctgtcaca cacacacaca cacacacaca     8040

cacacacaca cacacacaca cacacacaat gattggaggg ctatatgatc cagcattagc     8100

ttcctggtgt gccaagcatg cttgatcggg aatttttttt tattattatt attttttagc     8160

tgtagctgaa ggcatttctc ggatgtggag aggagaatgg aaatcgcaga accaaatcag     8220

tttgccctgc catatttggc tgtggtctgt cattgggcat ttctgatgtg cttttctgga     8280

ttcaggaaga gctgattgtc ctccgagggt tgaaaaaaaa aaaacagttt cagaaacctg     8340

aatccagggc cttatagttc tcctcattat ctatcttctt ctcccttccc tcgcccaagg     8400

gagtggggga aacacttttc actgcagagt ttgctttaaa gttttcccat cttgcgtgca     8460

ttatcccttg atattaaaat tattttctca gtttaatcca actcctgctg agaagctgtg     8520

tgagatttag gctgtggggt ttttttcttg tactcttttg gatggtgttg catttttcac     8580

tcttaacccg agggtgtgtt tcagcttatg ttcgttctgt ttcatgcagg tttatagcac     8640

ggtagagtag aaggcggctt ctgattttta gggtattttt agaattcatt cctgagtgag     8700

gggttcagac acccagtctc ctcggaacag gggtgagggg tcgactgagc tttgttgaga     8760

agcctccagt taggcttcgg gcgggtctcc atgttatatt gtgtgtttac tgagcttccc     8820

actggtagaa gatgacacat ttgtccatcg tcctgtgtat ctgctttcca gaggacaccg     8880

gagcattctc ctggggtcac tcccacatgg ctgcctcaca tagctgtttt gcaacagcct     8940

ttattgccaa cacccttgga agaacatctc ctgtagaagt acaagttttg caatatggac     9000

tttggaagtg gttttgtgat gttcgaattt tctgttagcc tattgctcaa gcactacaga     9060

atgtacatag tccctttggc catcctctca ccccagaata tcctaataaa cattgttttc     9120

ttttttaaaa aaaaaaaaaa aaaaa                                           9145


<210>  2554
<211>  8865
<212>  DNA
<213>  homo sapiens

<400>  2554
gtcactttca tgaattcaaa ggcaatttac cagtgatttc tgggtgctgg ggctgatatt       60

ttttgtgcat atttaagaat gtcttccaag caagccacct ctccatttgc ctgtgcagct      120

gatggagagg atgcaatgac ccaggattta acctcaaggg aaaaggaaga gggcagtgat      180

caacatgtgg cctcccatct gcctctgcac cccataatgc acaacaaacc tcactctgag      240

gagctaccaa cacttgtcag taccattcaa caagatgctg actgggacag cgttctgtca      300

tctcagcaaa gaatggaatc agagaataat aagttatgtt ccctatattc cttccgaaat      360

acctctacct caccacataa gcctgacgaa gggagtcggg accgtgagat aatgaccagt      420

gttacttttg gaaccccaga gcgccgcaaa gggagtcttg ccgatgtggt ggacacactg      480

aaacagaaga agcttgagga aatgactcgg actgaacaag aggattcctc ctgcatggaa      540

aaactacttt caaaagattg gaaggaaaaa atggaaagac taaataccag tgaacttctt      600

ggagaaatta aaggtacacc tgagagcctg gcagaaaaag aacggcagct ctccaccatg      660

attacccagc tgatcagttt acgggagcag ctactggcag cgcatgatga acagaaaaaa      720

ctggcagcgt cacaaattga gaaacaacgg cagcaaatgg accttgctcg ccaacagcaa      780

gaacagattg cgagacaaca gcagcaactt ctgcaacagc agcacaaaat taatctcctg      840

cagcaacaga tccaggttca gggtcacatg cctccgctca tgatcccaat ttttccacat      900

gaccagcgga ctctggcagc agctgctgct gcccaacagg gattcctctt cccccctgga      960

ataacataca aaccaggtga taactacccc gtacagttca ttccatcaac aatggcagct     1020

gctgctgctt ctggactcag ccctttacag ctccagaagg gtcatgtctc ccacccacaa     1080

attaaccaaa ggctaaaggg cctaagtgac cgttttggca ggaatttgga cacctttgaa     1140

catggtggtg gccactctta caaccacaaa cagattgagc agctctatgc cgctcagctg     1200

gccagcatgc aggtgtcacc tggagcaaag atgccatcaa ctccacagcc accaaacaca     1260

gcagggacgg tctcacctac tgggataaaa aatgaaaaga gagggaccag ccctgtaact     1320

caagttaagg atgaagcagc agcacagcct ctgaatctct catcccgacc caagacagca     1380

gagcctgtaa agtccccaac gtctcccacc cagaacctct tcccagccag caaaaccagc     1440

cctgtcaatc tgccaaacaa aagcagcatc cctagcccca ttggaggaag cctgggaaga     1500

ggatcctctt tagatatcct atctagtctc aactcccctg ccctttttgg ggatcaggat     1560

acagtgatga aagccattca ggaggcgcgg aagatgcgag agcagatcca gcgggagcaa     1620

cagcagcaac agccacatgg tgttgacggg aaactgtcct ccataaataa tatggggctg     1680

aacagctgca ggaatgaaaa ggaaagaacg cgctttgaga atttggggcc ccagttaacg     1740

ggaaagtcaa atgaagatgg aaaactgggc ccaggtgtca tcgaccttac tcggccagaa     1800

gatgcagagg gaggtgccac tgtggctgaa gcacgagtct acagggacgc ccgcggccgt     1860

gccagcagcg agccacacat taagcgacca atgaatgcat tcatggtttg ggcaaaggat     1920

gagaggagaa aaatccttca ggccttcccc gacatgcata actccaacat tagcaaaatc     1980

ttaggatctc gctggaaatc aatgtccaac caggagaagc aaccttatta tgaagagcag     2040

gcccggctaa gcaagatcca cttagagaag tacccaaact ataaatacaa accccgaccg     2100

aaacgcacct gcattgttga tggcaaaaag cttcggattg gggagtataa gcaactgatg     2160

aggtctcgga gacaggagat gaggcagttc tttactgtgg ggcaacagcc tcagattcca     2220

atcaccacag gaacaggtgt tgtgtatcct ggtgctatca ctatggcaac taccacacca     2280

tcgcctcaga tgacatctga ctgctctagc acctcggcca gcccggagcc cagcctcccg     2340

gtcatccaga gcacttatgg tatgaagaca gatggcggaa gcctagctgg aaatgaaatg     2400

atcaatggag aggatgaaat ggaaatgtat gatgactatg aagatgaccc caaatcagac     2460

tatagcagtg aaaatgaagc cccggaggct gtcagtgcca actgaggagt ttttgtttgc     2520

tgaattaaag tactctgaca tttcaccccc ctccccaaca aagagttatt aaagagcccg     2580

catgcatttg tggctccaca attacatcag cagaatggtc ttaattgttt cgtaaagtgt     2640

gagacagatt aagttttccc tgatttttca tgaacttgag ttttttgttg ttattgttat     2700

tgttgttgtt gttgtttttt taatttaggt gaagacatat taaatatgag acaccaggac     2760

ttgaaactta tctcaacccg tagatgtctt acaagtctta tatttttgtc ttactttttt     2820

tttcttttgg atgttgataa aggtttaagt tactgtttta gatggggtta aacattctca     2880

ctcaggtatg ctgtgccggc ctacaggttg tgaatgtgtt tttattctga attattttag     2940

aaaacaactg aggatttcat attgtgaaac agaacaagtc cacggcgtgt gcagctgcat     3000

gtagagcata ttcaaaaggc ctcggaattc caattttcca tttgtagagt taaactttga     3060

atgtgccaaa ctttttcgta acttttgaat cttaatattt tgaaagtctt aaaggagaca     3120

ctgcaaagtc ttagacaatc tttggcatct taaaataaaa tagcaaacca acattttttt     3180

ttccagaaaa tggtaaggta ctcaggaatc tggagacaag atattgtaag gaatgaacaa     3240

ggttgccaca gtgcatggac ccaattgtgt ttgcctgttg acgtgccatc agtgcgtgat     3300

gtggtatgac atacacacac cagagcaacc gccacaccag atatcgacag agtggtcttc     3360

tctgcctgag accacctctc actacatcca ttatcccttt gcctttaacc ctgacattca     3420

gtcttaacac attttatctt aaataattta ttcattccag aatgtcaagg gtccacttgc     3480

tatttatttt ttttcaattg ttggtggcat taatttaata attcttgttt ttcaccttcc     3540

ttccccgaag aacttttccg tccttttcac ctccttctcc tgtgtacata gtgattttat     3600

gtccccagaa cgcctggaag catttctgaa accaagatat tattaaaaac ctattattgt     3660

ttttaatcat gagtatgtat ctggctgcag ggctgtgtat tgggatatag gtatatagtc     3720

ttacacttaa acaggtatgc ccctgaggtt cactgtgacc tcaagtcttt tgccagaatt     3780

ttcccctaat tcagttcaca agtggtaggg tctgcatcag tggcatttcc ccctgaattc     3840

cattcagcag caaggttcaa cagtggtgac tgccaggcag gagagtcctg cggccaaacc     3900

tgaagcccaa ggctcgtggg ccatgcagga atctcagtga agctgtcatg ggctggcacc     3960

tttacactga gttgccttgt cccagctggc acatctaggg agttcattgc aaaatcccca     4020

ggatgcaaaa agccacatga cagcctcaga gcaaagatgg tggcaaatag tcatgataca     4080

tctagagaat gaaagaaaac tgtaagggag gagaaggagg ggaatacatt ccctatatgg     4140

gatgttccta ctgttaactc tggggaacag atagctccgg gggcagcaga tgagttcctc     4200

tggctgactc tatctgtagc cacatgggga cctgcctacg tgtgaacaaa atgaactgca     4260

cttatcacac aaggatttct ttgaagacat gctactgggg tgggaagcag tgaggtttta     4320

ttccccatct cctaactaca gggagctctg ccatgtcatt ttggccttcc tgaaactagg     4380

acaggttgtc tatcgggggg cttcccccag agaggtttag tgggagaatg tcagtgaatg     4440

ggatagttca cctcatggga caacccagaa tctgatcacc aggacatagg aatggcccca     4500

tcagatttct tgagccattt tgtcacttgg aagaaaatag tgtacctttg tatttattta     4560

agagtgctca aggcctaata gcaataaaca ggtctagcca agaaattaca agctattctg     4620

ttagctggga gtgctctcta taagctgatt aaggtactga taggaactct ttgttattca     4680

tgttggttgg ggattagaaa tttgtttttg tacatttatt tcaaatgagg aggaggtcat     4740

tttttctctc aaaaaatgag tatttattat tgtcttactg atttctttga ttatatacct     4800

ctcctcctca gttcactctt gttttttttc tttctctttg gcttttgctt ttgctctctc     4860

tcacttcttt cttattttgt tgcattggta gagtgttgta tggctagcat tgtattgtat     4920

gtaattaatt ttgcacaaaa gcaaacattt agcatagtag gttaattttg tttgttttta     4980

tgaccatgcc aaaataatat tctgggctgg tggagaacaa aggactgttc tttaggactg     5040

aaacttgatt ttgctcatag taagtaaaaa aaaacaaaaa acacacacac tcacagatgt     5100

tgtttcgtaa gtgttataag cactggatat aaatggtatt ttttatcact tctgactaat     5160

gtgaaactgt tgtacgaaaa ctacatgaac aaaagtcatc tgtttcgact cgtgtgggct     5220

tgcctcacag ttgccggatt tgagtcattt ttatgtcttg ttatttcatt tatttatgca     5280

aaatacatgt gtgtatgaac actttgtttt agctccagct ctgcctcagt actggggttc     5340

atttactttt agccatgttc ttaaaaatga aaggctattc aggaatgatc tgattgtaaa     5400

cgtctttttc attggatcaa acagtaatgc tgtatttgaa tctaaatttt gtgtataagc     5460

agtttattta ttagccaagt ttggctctaa atatccatgg aaattaagaa tgacaatcat     5520

agggatcaat tcattttatt ttcagtgggg cttaaacaaa gtttatatga ctttaccatc     5580

tcattttaga tttttctaat tgtgtaaata taacatagaa atagaattta tttttggttc     5640

atgaatactt agtgagatat aagttatgta tttccttttt gttctctatc catagatgtt     5700

ggtccaaact gaaagttgat gagtcactgt gcctctcggg gtagtgagtt atcagctaca     5760

gtgagagagc agtgtttggc ctgcagctgg gacagcaaaa cgtttcacca gggttctcat     5820

gcagttcaga acccactgtc cacagatcca gacatttccc ttttttctta cagaaagttg     5880

atgattggac atactaaatt tccactacag ttaggagaca gtcagtttgc tttgggagtc     5940

tacataaatc ttctaagata gttctgtgac catttaatag caagaagcat gaatgccact     6000

acaaaggcaa aaatccacct ctgagatcgg ccgttaataa acgtcccgtc atgtcagttt     6060

agattcaaga atgttaagca actttgtttt tgcggtgctc cctatttcat agtatcttca     6120

aatcaaaaat aaaaattatc tccattttgt taaagaactt acagggtcag ggttctcctt     6180

gtcacttaga attgggacac tgccaggcaa tcctctccca aaaaaaaaaa aaaaaaaaaa     6240

tagccatatg gaatggaagg aaaaggagaa aagaaggaag aaaggaaaaa agtaggaagg     6300

gagagagaaa aaaaaggtcg ctttgcggat acgagccgct aggctgacaa cttttctatt     6360

tcattggcag atatgaagca gtgtcttttc cagtaaggta cggaagcttt gttgttttca     6420

tgtgtaccca gctcagcctt ttagaagcac ctcggtttgc ttcattaggt atttgatact     6480

ctccagcctt gtcctcaggc ctgatttgat ttgccagggt cctgacacca aagcccaggc     6540

caagttctaa attcaggtgt gggctcacag tgctattgag cttgtcgaat tctggcctcc     6600

cctgaacatt agccccacgg gagcctgagg gtgtttgaaa agggcgtgat cactctaggg     6660

ctgaaattaa aggctgcttt cttttccttc tgaagccagg ctgcttcttc ggagtacacc     6720

ctcctgagcc aggagcacaa gcactagcag aaagcaggga ttgtttcagg aaagcccatt     6780

taccctcagt aggaaggcag cctggtcact tgaacagcac agctgaggct gcttctctca     6840

atttactcat tttgcaaaga attgacctct accaactcat tagggagagg aaaaagaatc     6900

acttagtaat tttaaatcat atgagaagtc ctgtaccaag tgccaacaac tgcaaagaaa     6960

tgcagctaga ggaatgtatt gaaattacta ctgggtcttc ctttttaatg agaaaatgac     7020

aaaaatggtt gctgtagccc tgcctgattt tgtacacgtt tgtctaagaa ttgagttggc     7080

acttaagctc acttctcaaa gtataataat attgtatgac ctcatttgtc ctttcacaaa     7140

agcacttgca tcatttcctt aagtcatctg ctccctgaca tgttttcttc cctaataaac     7200

aacttctgtc tgttattcct gccaatgatg ttctgtttct gatgccatat cctattgagc     7260

gtgcccctgt actaatatca ttgaaaatat tgatatgcaa acacatttcc ttttcatccc     7320

cattctatct ttccctttgg ggacagattg ctttccaaaa gctcatgaac aaatatttgg     7380

aatgctggta cctttggggc agaggtaagg gtgggcgggg tgggggcaga aaggtaatgc     7440

ttaatgcaga taactcttct aatcagtgtc catggcaata tgaacgcttg aagaaaactc     7500

agtgacatat cttgctcagt agtttcttat tcctgaagaa ccacaagcat aaagtgaggc     7560

ctcagtgctg gtgctcttgg agtatgggga atgtgcaaat atttaactgt tttgtatgct     7620

gcacattgca ggtctgctca tgtgcattct ccctttgtct tcctttgtca tatgtgtttt     7680

tgcttttttg aaagtgcagt ctttattgta ccctcctcca gcttgtagca aattagaatg     7740

cttagcattt atgttcattc attattgtat ttgccatgta aaatttttat taccttagac     7800

aagcttataa gctgttacta cataacttat cttactgtaa ctcttttatt tcccccgacg     7860

ttgtaatttg tttgtgatgt atattgtgaa attgtattct atgttaattt aatcagcaca     7920

attcactgac atgctggact gacatgctgg ctgctgtttc aaagtgtaaa gtttgtgtag     7980

ggctgttggg acaactgcaa ctctgttgtc aaggtactgt gctttggttc ctatagcaac     8040

actgggtgtg gcccttgaat tgctaagggc atttaataca tcctggagca aattttaact     8100

gcagattttc tttgtagaaa ttctatgtat aatgcaggta cctacttggc ccatggctgg     8160

taactatttg ggcaattaga aaaaaagaaa aaaacataaa aactagtgtc tattgctgct     8220

ttgaatatgt ttgaaagtct gaaaatgtaa atagtttatc aaaaaaaaat cttgtacagt     8280

ccagtgtaaa gtttttaaat gaccttaagg gttgccatca catctttctc acactctcct     8340

cttgataata ataataataa aaagtttgct aaggattaaa gaaatgggaa aaataaaaaa     8400

aatctcttca aatttacagg aatgaatcat tgttcttagc tttgttgcat acacaaactt     8460

cttggatttt gttgtgcagt attgacgtga gataaagctc aacattgaat aatctttcag     8520

tggtactttt caaagtcttc ccctcctctg cctcataatt aagggaaaag acaaaattga     8580

aagacacact gtctttatct atcctggtgt atgttggcac cttagctact tttttttttt     8640

cctttttgca caaggtgctt tcctgatatg ttcaacatgc catctttggg tgataatgta     8700

tatgccgtga tggggctcag gccccttagg ggagtgtcta taagaactgc ctatttatgc     8760

tcatttacct caagactgtc ctctctaccc taatctagtt gtcatcactc catcttttgt     8820

actgctgttg acacttacaa attaaagata aattttgttt tatga                     8865


<210>  2555
<211>  4187
<212>  DNA
<213>  homo sapiens

<400>  2555
tagagaacgt ggctcccgcg ggggcgctcg gagccgccgc acaggtagcg agagcgcggc       60

gccttctcct tcctttgtga gccgccgggc agggcaccga cctcgggttc tcccggcgcc      120

tccactgcag ggatctctag cctcgcacct cctcccctcg tcgcctgccc accctctgct      180

cctctcctgg cgccggggac cctgcccctt tgcgcctttt cctggctctg cctcggcttc      240

catttttctc tgcttccgaa aagccagtgg ggaagggcgg gggagacctg ccagtcctcc      300

cagacttctc ccgggttgct ccagctggcc ctcctcgccc cttcccggga gaggcacatg      360

gagagacatg aatcagggga gtggactgga cctgctgaag atctcatatg gaaaaggagc      420

cagaaggaaa aacagattta aaggatctga tggaagcacg tcatctgata ctacctcaaa      480

tagttttgtt cgccagggtt cggcagactc ctacactagc cgtccatccg attccgatgt      540

atctctggag gaggaccggg aggcagtgcg cagagaagcg gagcggcagg cccaggcaca      600

gttggaaaaa gcaaagacaa agcccgttgc atttgcggtt cggacaaatg tcagctacag      660

tgcggcccat gaagatgatg ttccagtgcc tggcatggcc atctcattcg aagcaaaaga      720

ttttctgcat gttaaggaaa aatttaacaa tgactggtgg atagggcgat tggtaaaaga      780

aggctgtgaa atcggattca ttccaagccc agtcaaacta gaaaacatga ggctgcagca      840

tgaacagaga gccaagcaag ggaaattcta ctccagtaaa tcaggaggaa attcatcatc      900

cagtttgggt gacatagtac ctagttccag aaaatcaaca cctccatcat ctgctaagca      960

gaagcagaaa tcgacagagc acactcctcc gtatgatgtg gtaccttcca tgcgaccagt     1020

ggtcctagtg ggcccttctc tgaagggcta cgaggtcaca gatatgatgc aaaaagcgct     1080

gtttgatttt ttaaaacaca gatttgaagg gcggatatcc atcacaaggg tcaccgctga     1140

catctcgctt gccaaacgct cggtattaaa caatcccagt aagcacgcaa taatagaaag     1200

atccaacaca aggtcaagct tagcggaagt tcagagtgaa atcgaaagga tttttgaact     1260

tgcaagaaca ttgcagttgg tggtccttga cgcggataca attaatcatc cagctcaact     1320

cagtaaaacc tccttggccc ctattatagt atatgtaaag atttcttctc ctaaggtttt     1380

acaaaggtta ataaaatctc gagggaaatc tcaagctaaa cacctcaacg tccagatggt     1440

agcagctgat aaactggctc agtgtcctcc agagctgttc gatgtgatct tggatgagaa     1500

ccagcttgag gatgcctgtg agcaccttgc cgactatctg gaggcctact ggaaggccac     1560

ccatcctccc agcagtagcc tccccaaccc tctccttagc cgtacattag ccacttcaag     1620

tctgcctctt agccccaccc tagcctctaa ttcacagggt tctcaaggtg atcagaggac     1680

tgatcgctcc gctcctatcc gttctgcttc ccaagctgaa gaagaaccta gtgtggaacc     1740

agtcaagaaa tcccagcacc gctcttcctc ctcagcccca caccacaacc atcgcagtgg     1800

gacaagtcgc ggcctctcca ggcaagagac atttgactcg gaaacccagg agagtcgaga     1860

ctctgcctac gtagagccaa aggaagatta ttcccatgac cacgtggacc actatgcctc     1920

acaccgtgac cacaaccaca gagacgagac ccacgggagc agtgaccaca gacacaggga     1980

gtcccggcac cgttcccggg acgtggatcg agagcaggac cacaacgagt gcaacaagca     2040

gcgcagccgt cataaatcca aggatcgcta ctgtgaaaag gatggagaag tgatatcaaa     2100

aaaacggaat gaggctgggg agtggaacag ggatgtttac atccgccaat gagttttgcc     2160

cgtttgtgtt tttttttttt tttttttgaa gtcttgtata actaacagca tccccaaaac     2220

aaagtctttg gggtctacac tgcaatcata tgtgatctgt cttgtaatat tttgtattat     2280

tgctgttgct tgaatagcaa tagcatggat agagtattga gatacttttt cttttgtaag     2340

tgctacataa attggcctgg tatggctgca gtcctccggt tgcatactgg actcttcaaa     2400

aactgttttg ggtagctgcc acttgaacaa aatctgttgc cacccaggtg atgttagtgt     2460

tttaagaaat gtagttgatg tatccaacaa gccagaatca gcacagataa aaagtggaat     2520

ttcttgtttc tccagatttt taatacgtta atacgcaggc atctgatttg catattcatt     2580

catggaccac tgtttcttgc ttgtacctct ggctgactaa atttggggac agattcagtc     2640

ttgccttaca caaaggggat cataaagtta gaatctattt tctatgtact agtactgtgt     2700

actgtataga cagtttgtaa atgttatttc tgcaaacaaa caccttctta ttatatatat     2760

aatatatata tatatcagtt tgatcacact attttagagt cttaatgcca agtcagcaga     2820

tttgctttat gaattacagg gactagaaat gcccacattc aggaaatttg taataacatt     2880

gtctagacac ctatcctcat tctagtagaa agtgtgtaca tactgtaaat atgtgtgatt     2940

gcttgacttg aaaaggtttg aattctgaat gttataccat ccttgtaagt aagtttgtaa     3000

tttccaccat aaattatggt aaatataaaa ctccagaggt tgttctactc catacagttc     3060

acactgattg tgacacattc ttagtagcta gtgtctgttc tagtcactgc actggagtct     3120

acgagccgga actcgctata tgcacgtgtg tgtgtccgta tgtaagaaag tgtgcaccga     3180

gtgactgaat ggttgagatg aattggaatg ctgaagacta acgaagaaac tagagactga     3240

tatcgagcat tctgcccacc tcgctctgta tttaattaat tgtgctatat gttgctttaa     3300

caacccattg agcagtcagg gaatgtgagt aagcttgctg ccaaaggtaa ctaggaaagc     3360

attcatctgc tgcctccttg tttttgctcc tagagagtga aaatacaggc aattttactg     3420

tgagtgtttc actggaaatg tacaatcttt gtgtgttaga gtatttgttt tagtaagaaa     3480

tgtttacaca gcttgtggaa ttatttcgtg ggaaaataaa tttttataac ttctcccact     3540

tcaatttcta accttgccta ttgttcctgt tgtttgttta cctcccagtt acctaccatt     3600

cctccccacc accgactcca gcaggttcac tgtctgtcag aacccagaag tgcttcttat     3660

aaccaaagtt tctgttcttc agaagaaatc agggcaaaat ggggtgactt gaagtgaata     3720

aaatgttaag aatattatcc tacataagac atgtacacag aaggggaacc ttgaagacat     3780

tatctccatg cctcaattac actgctgtaa gaagcttaca atgtcatcat gtttaaggct     3840

aagacctttt ccgtgtctca agtgtatatt ttgtccagtt ataactggat ggtaagacag     3900

tattaagagt gcaagtacct ggcacttgaa gtttgtccca ggaaaatgcc tgtgtataat     3960

tacctaactt cagatctgca cattaactta tttaacaaaa taaatcagcc gggcgcagtg     4020

gctcatgcct gtaatcccag caatttggga ggctgaggag ggtggatcac ctgaggtcag     4080

gagttcaaga ccagcctggc caacgtggcg aaaccccgtc tctactaaaa agataaaaaa     4140

ttagccaggt gtggtggtgc acacctgtaa tcccagctac ttgggag                   4187


<210>  2556
<211>  4078
<212>  DNA
<213>  homo sapiens

<400>  2556
gaggaggagg ggacccgccg ccgggggctg gctgcttcgc tccgagccga cttttcgcca       60

atggtccaaa gggacatgtc caagtcgcct cccacagcgg cggcggcggt ggcgcaggag      120

atccagatgg aactgctaga gaacgtggct cccgcggggg cgctcggagc cgccgcacag      180

tcatatggaa aaggagccag aaggaaaaac agatttaaag gatctgatgg aagcacgtca      240

tctgatacta cctcaaatag ttttgttcgc cagggttcgg cagactccta cactagccgt      300

ccatccgatt ccgatgtatc tctggaggag gaccgggagg cagtgcgcag agaagcggag      360

cggcaggccc aggcacagtt ggaaaaagca aagacaaagc ccgttgcatt tgcggttcgg      420

acaaatgtca gctacagtgc ggcccatgaa gatgatgttc cagtgcctgg catggccatc      480

tcattcgaag caaaagattt tctgcatgtt aaggaaaaat ttaacaatga ctggtggata      540

gggcgattgg taaaagaagg ctgtgaaatc ggattcattc caagcccagt caaactagaa      600

aacatgaggc tgcagcatga acagagagcc aagcaaggga aattctactc cagtaaatca      660

ggaggaaatt catcatccag tttgggtgac atagtaccta gttccagaaa atcaacacct      720

ccatcatctg ctatagacat agatgctact ggcttagatg cagaagaaaa tgatattcca      780

gcaaaccacc gctcccctaa acccagtgca aacagtgtaa cgtcacccca ctccaaagag      840

aaaagaatgc ccttctttaa gaagacagag cacactcctc cgtatgatgt ggtaccttcc      900

atgcgaccag tggtcctagt gggcccttct ctgaagggct acgaggtcac agatatgatg      960

caaaaagcgc tgtttgattt tttaaaacac agatttgaag ggcggatatc catcacaagg     1020

gtcaccgctg acatctcgct tgccaaacgc tcggtattaa acaatcccag taagcacgca     1080

ataatagaaa gatccaacac aaggtcaagc ttagcggaag ttcagagtga aatcgaaagg     1140

atttttgaac ttgcaagaac attgcagttg gtggtccttg acgcggatac aattaatcat     1200

ccagctcaac tcagtaaaac ctccttggcc cctattatag tatatgtaaa gatttcttct     1260

cctaaggttt tacaaaggtt aataaaatct cgagggaaat ctcaagctaa acacctcaac     1320

gtccagatgg tagcagctga taaactggct cagtgtcctc cagagctgtt cgatgtgatc     1380

ttggatgaga accagcttga ggatgcctgt gagcaccttg ccgactatct ggaggcctac     1440

tggaaggcca cccatcctcc cagcagtagc ctccccaacc ctctccttag ccgtacatta     1500

gccacttcaa gtctgcctct tagccccacc ctagcctcta attcacaggg ttctcaaggt     1560

gatcagagga ctgatcgctc cgctcctatc cgttctgctt cccaagctga agaagaacct     1620

agtgtggaac cagtcaagaa atcccagcac cgctcttcct cctcagcccc acaccacaac     1680

catcgcagtg ggacaagtcg cggcctctcc aggcaagaga catttgactc ggaaacccag     1740

gagagtcgag actctgccta cgtagagcca aaggaagatt attcccatga ccacgtggac     1800

cactatgcct cacaccgtga ccacaaccac agagacgaga cccacgggag cagtgaccac     1860

agacacaggg agtcccggca ccgttcccgg gacgtggatc gagagcagga ccacaacgag     1920

tgcaacaagc agcgcagccg tcataaatcc aaggatcgct actgtgaaaa ggatggagaa     1980

gtgatatcaa aaaaacggaa tgaggctggg gagtggaaca gggatgttta catccgccaa     2040

tgagttttgc ccgtttgtgt tttttttttt ttttttttga agtcttgtat aactaacagc     2100

atccccaaaa caaagtcttt ggggtctaca ctgcaatcat atgtgatctg tcttgtaata     2160

ttttgtatta ttgctgttgc ttgaatagca atagcatgga tagagtattg agatactttt     2220

tcttttgtaa gtgctacata aattggcctg gtatggctgc agtcctccgg ttgcatactg     2280

gactcttcaa aaactgtttt gggtagctgc cacttgaaca aaatctgttg ccacccaggt     2340

gatgttagtg ttttaagaaa tgtagttgat gtatccaaca agccagaatc agcacagata     2400

aaaagtggaa tttcttgttt ctccagattt ttaatacgtt aatacgcagg catctgattt     2460

gcatattcat tcatggacca ctgtttcttg cttgtacctc tggctgacta aatttgggga     2520

cagattcagt cttgccttac acaaagggga tcataaagtt agaatctatt ttctatgtac     2580

tagtactgtg tactgtatag acagtttgta aatgttattt ctgcaaacaa acaccttctt     2640

attatatata taatatatat atatatcagt ttgatcacac tattttagag tcttaatgcc     2700

aagtcagcag atttgcttta tgaattacag ggactagaaa tgcccacatt caggaaattt     2760

gtaataacat tgtctagaca cctatcctca ttctagtaga aagtgtgtac atactgtaaa     2820

tatgtgtgat tgcttgactt gaaaaggttt gaattctgaa tgttatacca tccttgtaag     2880

taagtttgta atttccacca taaattatgg taaatataaa actccagagg ttgttctact     2940

ccatacagtt cacactgatt gtgacacatt cttagtagct agtgtctgtt ctagtcactg     3000

cactggagtc tacgagccgg aactcgctat atgcacgtgt gtgtgtccgt atgtaagaaa     3060

gtgtgcaccg agtgactgaa tggttgagat gaattggaat gctgaagact aacgaagaaa     3120

ctagagactg atatcgagca ttctgcccac ctcgctctgt atttaattaa ttgtgctata     3180

tgttgcttta acaacccatt gagcagtcag ggaatgtgag taagcttgct gccaaaggta     3240

actaggaaag cattcatctg ctgcctcctt gtttttgctc ctagagagtg aaaatacagg     3300

caattttact gtgagtgttt cactggaaat gtacaatctt tgtgtgttag agtatttgtt     3360

ttagtaagaa atgtttacac agcttgtgga attatttcgt gggaaaataa atttttataa     3420

cttctcccac ttcaatttct aaccttgcct attgttcctg ttgtttgttt acctcccagt     3480

tacctaccat tcctccccac caccgactcc agcaggttca ctgtctgtca gaacccagaa     3540

gtgcttctta taaccaaagt ttctgttctt cagaagaaat cagggcaaaa tggggtgact     3600

tgaagtgaat aaaatgttaa gaatattatc ctacataaga catgtacaca gaaggggaac     3660

cttgaagaca ttatctccat gcctcaatta cactgctgta agaagcttac aatgtcatca     3720

tgtttaaggc taagaccttt tccgtgtctc aagtgtatat tttgtccagt tataactgga     3780

tggtaagaca gtattaagag tgcaagtacc tggcacttga agtttgtccc aggaaaatgc     3840

ctgtgtataa ttacctaact tcagatctgc acattaactt atttaacaaa ataaatcagc     3900

cgggcgcagt ggctcatgcc tgtaatccca gcaatttggg aggctgagga gggtggatca     3960

cctgaggtca ggagttcaag accagcctgg ccaacgtggc gaaaccccgt ctctactaaa     4020

aagataaaaa attagccagg tgtggtggtg cacacctgta atcccagcta cttgggag       4078


<210>  2557
<211>  3964
<212>  DNA
<213>  homo sapiens

<400>  2557
gaggaggagg ggacccgccg ccgggggctg gctgcttcgc tccgagccga cttttcgcca       60

atggtccaaa gggacatgtc caagtcgcct cccacagcgg cggcggcggt ggcgcaggag      120

atccagatgg aactgctaga gaacgtggct cccgcggggg cgctcggagc cgccgcacag      180

tcatatggaa aaggagccag aaggaaaaac agatttaaag gatctgatgg aagcacgtca      240

tctgatacta cctcaaatag ttttgttcgc cagggttcgg cagactccta cactagccgt      300

ccatccgatt ccgatgtatc tctggaggag gaccgggagg cagtgcgcag agaagcggag      360

cggcaggccc aggcacagtt ggaaaaagca aagacaaagc ccgttgcatt tgcggttcgg      420

acaaatgtca gctacagtgc ggcccatgaa gatgatgttc cagtgcctgg catggccatc      480

tcattcgaag caaaagattt tctgcatgtt aaggaaaaat ttaacaatga ctggtggata      540

gggcgattgg taaaagaagg ctgtgaaatc ggattcattc caagcccagt caaactagaa      600

aacatgaggc tgcagcatga acagagagcc aagcaaggga aattctactc cagtaaatca      660

ggaggaaatt catcatccag tttgggtgac atagtaccta gttccagaaa atcaacacct      720

ccatcatctg ctaagcagaa gcagaaatcg acagagcaca ctcctccgta tgatgtggta      780

ccttccatgc gaccagtggt cctagtgggc ccttctctga agggctacga ggtcacagat      840

atgatgcaaa aagcgctgtt tgatttttta aaacacagat ttgaagggcg gatatccatc      900

acaagggtca ccgctgacat ctcgcttgcc aaacgctcgg tattaaacaa tcccagtaag      960

cacgcaataa tagaaagatc caacacaagg tcaagcttag cggaagttca gagtgaaatc     1020

gaaaggattt ttgaacttgc aagaacattg cagttggtgg tccttgacgc ggatacaatt     1080

aatcatccag ctcaactcag taaaacctcc ttggccccta ttatagtata tgtaaagatt     1140

tcttctccta aggttttaca aaggttaata aaatctcgag ggaaatctca agctaaacac     1200

ctcaacgtcc agatggtagc agctgataaa ctggctcagt gtcctccaga gctgttcgat     1260

gtgatcttgg atgagaacca gcttgaggat gcctgtgagc accttgccga ctatctggag     1320

gcctactgga aggccaccca tcctcccagc agtagcctcc ccaaccctct ccttagccgt     1380

acattagcca cttcaagtct gcctcttagc cccaccctag cctctaattc acagggttct     1440

caaggtgatc agaggactga tcgctccgct cctatccgtt ctgcttccca agctgaagaa     1500

gaacctagtg tggaaccagt caagaaatcc cagcaccgct cttcctcctc agccccacac     1560

cacaaccatc gcagtgggac aagtcgcggc ctctccaggc aagagacatt tgactcggaa     1620

acccaggaga gtcgagactc tgcctacgta gagccaaagg aagattattc ccatgaccac     1680

gtggaccact atgcctcaca ccgtgaccac aaccacagag acgagaccca cgggagcagt     1740

gaccacagac acagggagtc ccggcaccgt tcccgggacg tggatcgaga gcaggaccac     1800

aacgagtgca acaagcagcg cagccgtcat aaatccaagg atcgctactg tgaaaaggat     1860

ggagaagtga tatcaaaaaa acggaatgag gctggggagt ggaacaggga tgtttacatc     1920

cgccaatgag ttttgcccgt ttgtgttttt tttttttttt ttttgaagtc ttgtataact     1980

aacagcatcc ccaaaacaaa gtctttgggg tctacactgc aatcatatgt gatctgtctt     2040

gtaatatttt gtattattgc tgttgcttga atagcaatag catggataga gtattgagat     2100

actttttctt ttgtaagtgc tacataaatt ggcctggtat ggctgcagtc ctccggttgc     2160

atactggact cttcaaaaac tgttttgggt agctgccact tgaacaaaat ctgttgccac     2220

ccaggtgatg ttagtgtttt aagaaatgta gttgatgtat ccaacaagcc agaatcagca     2280

cagataaaaa gtggaatttc ttgtttctcc agatttttaa tacgttaata cgcaggcatc     2340

tgatttgcat attcattcat ggaccactgt ttcttgcttg tacctctggc tgactaaatt     2400

tggggacaga ttcagtcttg ccttacacaa aggggatcat aaagttagaa tctattttct     2460

atgtactagt actgtgtact gtatagacag tttgtaaatg ttatttctgc aaacaaacac     2520

cttcttatta tatatataat atatatatat atcagtttga tcacactatt ttagagtctt     2580

aatgccaagt cagcagattt gctttatgaa ttacagggac tagaaatgcc cacattcagg     2640

aaatttgtaa taacattgtc tagacaccta tcctcattct agtagaaagt gtgtacatac     2700

tgtaaatatg tgtgattgct tgacttgaaa aggtttgaat tctgaatgtt ataccatcct     2760

tgtaagtaag tttgtaattt ccaccataaa ttatggtaaa tataaaactc cagaggttgt     2820

tctactccat acagttcaca ctgattgtga cacattctta gtagctagtg tctgttctag     2880

tcactgcact ggagtctacg agccggaact cgctatatgc acgtgtgtgt gtccgtatgt     2940

aagaaagtgt gcaccgagtg actgaatggt tgagatgaat tggaatgctg aagactaacg     3000

aagaaactag agactgatat cgagcattct gcccacctcg ctctgtattt aattaattgt     3060

gctatatgtt gctttaacaa cccattgagc agtcagggaa tgtgagtaag cttgctgcca     3120

aaggtaacta ggaaagcatt catctgctgc ctccttgttt ttgctcctag agagtgaaaa     3180

tacaggcaat tttactgtga gtgtttcact ggaaatgtac aatctttgtg tgttagagta     3240

tttgttttag taagaaatgt ttacacagct tgtggaatta tttcgtggga aaataaattt     3300

ttataacttc tcccacttca atttctaacc ttgcctattg ttcctgttgt ttgtttacct     3360

cccagttacc taccattcct ccccaccacc gactccagca ggttcactgt ctgtcagaac     3420

ccagaagtgc ttcttataac caaagtttct gttcttcaga agaaatcagg gcaaaatggg     3480

gtgacttgaa gtgaataaaa tgttaagaat attatcctac ataagacatg tacacagaag     3540

gggaaccttg aagacattat ctccatgcct caattacact gctgtaagaa gcttacaatg     3600

tcatcatgtt taaggctaag accttttccg tgtctcaagt gtatattttg tccagttata     3660

actggatggt aagacagtat taagagtgca agtacctggc acttgaagtt tgtcccagga     3720

aaatgcctgt gtataattac ctaacttcag atctgcacat taacttattt aacaaaataa     3780

atcagccggg cgcagtggct catgcctgta atcccagcaa tttgggaggc tgaggagggt     3840

ggatcacctg aggtcaggag ttcaagacca gcctggccaa cgtggcgaaa ccccgtctct     3900

actaaaaaga taaaaaatta gccaggtgtg gtggtgcaca cctgtaatcc cagctacttg     3960

ggag                                                                  3964


<210>  2558
<211>  4098
<212>  DNA
<213>  homo sapiens

<400>  2558
gactttgatg agctcctctg ctctgcctaa gtggttctgg aacagagagc tgttgtgatc       60

cgacgaactt tagaaagtca cactaactaa gactacacac cccaagccag caagaaaaag      120

gaaagcagtt gctatgctgt tcagcaaagc aagacttggc tgccttttag ctagtcctga      180

attcttgctc ctgtgaagaa aattcctgct ggagtgctgg gcgcacttgg aattggtcta      240

gcatgcttga cagacgcctt atagctcctc aaactaaata cattattcct gggggttcgg      300

cagactccta cactagccgt ccatccgatt ccgatgtatc tctggaggag gaccgggagg      360

cagtgcgcag agaagcggag cggcaggccc aggcacagtt ggaaaaagca aagacaaagc      420

ccgttgcatt tgcggttcgg acaaatgtca gctacagtgc ggcccatgaa gatgatgttc      480

cagtgcctgg catggccatc tcattcgaag caaaagattt tctgcatgtt aaggaaaaat      540

ttaacaatga ctggtggata gggcgattgg taaaagaagg ctgtgaaatc ggattcattc      600

caagcccagt caaactagaa aacatgaggc tgcagcatga acagagagcc aagcaaggga      660

aattctactc cagtaaatca ggaggaaatt catcatccag tttgggtgac atagtaccta      720

gttccagaaa atcaacacct ccatcatctg ctatagacat agatgctact ggcttagatg      780

cagaagaaaa tgatattcca gcaaaccacc gctcccctaa acccagtgca aacagtgtaa      840

cgtcacccca ctccaaagag aaaagaatgc ccttctttaa gaagacagag cacactcctc      900

cgtatgatgt ggtaccttcc atgcgaccag tggtcctagt gggcccttct ctgaagggct      960

acgaggtcac agatatgatg caaaaagcgc tgtttgattt tttaaaacac agatttgaag     1020

ggcggatatc catcacaagg gtcaccgctg acatctcgct tgccaaacgc tcggtattaa     1080

acaatcccag taagcacgca ataatagaaa gatccaacac aaggtcaagc ttagcggaag     1140

ttcagagtga aatcgaaagg atttttgaac ttgcaagaac attgcagttg gtggtccttg     1200

acgcggatac aattaatcat ccagctcaac tcagtaaaac ctccttggcc cctattatag     1260

tatatgtaaa gatttcttct cctaaggttt tacaaaggtt aataaaatct cgagggaaat     1320

ctcaagctaa acacctcaac gtccagatgg tagcagctga taaactggct cagtgtcctc     1380

cagagctgtt cgatgtgatc ttggatgaga accagcttga ggatgcctgt gagcaccttg     1440

ccgactatct ggaggcctac tggaaggcca cccatcctcc cagcagtagc ctccccaacc     1500

ctctccttag ccgtacatta gccacttcaa gtctgcctct tagccccacc ctagcctcta     1560

attcacaggg ttctcaaggt gatcagagga ctgatcgctc cgctcctatc cgttctgctt     1620

cccaagctga agaagaacct agtgtggaac cagtcaagaa atcccagcac cgctcttcct     1680

cctcagcccc acaccacaac catcgcagtg ggacaagtcg cggcctctcc aggcaagaga     1740

catttgactc ggaaacccag gagagtcgag actctgccta cgtagagcca aaggaagatt     1800

attcccatga ccacgtggac cactatgcct cacaccgtga ccacaaccac agagacgaga     1860

cccacgggag cagtgaccac agacacaggg agtcccggca ccgttcccgg gacgtggatc     1920

gagagcagga ccacaacgag tgcaacaagc agcgcagccg tcataaatcc aaggatcgct     1980

actgtgaaaa ggatggagaa gtgatatcaa aaaaacggaa tgaggctggg gagtggaaca     2040

gggatgttta catccgccaa tgagttttgc ccgtttgtgt tttttttttt ttttttttga     2100

agtcttgtat aactaacagc atccccaaaa caaagtcttt ggggtctaca ctgcaatcat     2160

atgtgatctg tcttgtaata ttttgtatta ttgctgttgc ttgaatagca atagcatgga     2220

tagagtattg agatactttt tcttttgtaa gtgctacata aattggcctg gtatggctgc     2280

agtcctccgg ttgcatactg gactcttcaa aaactgtttt gggtagctgc cacttgaaca     2340

aaatctgttg ccacccaggt gatgttagtg ttttaagaaa tgtagttgat gtatccaaca     2400

agccagaatc agcacagata aaaagtggaa tttcttgttt ctccagattt ttaatacgtt     2460

aatacgcagg catctgattt gcatattcat tcatggacca ctgtttcttg cttgtacctc     2520

tggctgacta aatttgggga cagattcagt cttgccttac acaaagggga tcataaagtt     2580

agaatctatt ttctatgtac tagtactgtg tactgtatag acagtttgta aatgttattt     2640

ctgcaaacaa acaccttctt attatatata taatatatat atatatcagt ttgatcacac     2700

tattttagag tcttaatgcc aagtcagcag atttgcttta tgaattacag ggactagaaa     2760

tgcccacatt caggaaattt gtaataacat tgtctagaca cctatcctca ttctagtaga     2820

aagtgtgtac atactgtaaa tatgtgtgat tgcttgactt gaaaaggttt gaattctgaa     2880

tgttatacca tccttgtaag taagtttgta atttccacca taaattatgg taaatataaa     2940

actccagagg ttgttctact ccatacagtt cacactgatt gtgacacatt cttagtagct     3000

agtgtctgtt ctagtcactg cactggagtc tacgagccgg aactcgctat atgcacgtgt     3060

gtgtgtccgt atgtaagaaa gtgtgcaccg agtgactgaa tggttgagat gaattggaat     3120

gctgaagact aacgaagaaa ctagagactg atatcgagca ttctgcccac ctcgctctgt     3180

atttaattaa ttgtgctata tgttgcttta acaacccatt gagcagtcag ggaatgtgag     3240

taagcttgct gccaaaggta actaggaaag cattcatctg ctgcctcctt gtttttgctc     3300

ctagagagtg aaaatacagg caattttact gtgagtgttt cactggaaat gtacaatctt     3360

tgtgtgttag agtatttgtt ttagtaagaa atgtttacac agcttgtgga attatttcgt     3420

gggaaaataa atttttataa cttctcccac ttcaatttct aaccttgcct attgttcctg     3480

ttgtttgttt acctcccagt tacctaccat tcctccccac caccgactcc agcaggttca     3540

ctgtctgtca gaacccagaa gtgcttctta taaccaaagt ttctgttctt cagaagaaat     3600

cagggcaaaa tggggtgact tgaagtgaat aaaatgttaa gaatattatc ctacataaga     3660

catgtacaca gaaggggaac cttgaagaca ttatctccat gcctcaatta cactgctgta     3720

agaagcttac aatgtcatca tgtttaaggc taagaccttt tccgtgtctc aagtgtatat     3780

tttgtccagt tataactgga tggtaagaca gtattaagag tgcaagtacc tggcacttga     3840

agtttgtccc aggaaaatgc ctgtgtataa ttacctaact tcagatctgc acattaactt     3900

atttaacaaa ataaatcagc cgggcgcagt ggctcatgcc tgtaatccca gcaatttggg     3960

aggctgagga gggtggatca cctgaggtca ggagttcaag accagcctgg ccaacgtggc     4020

gaaaccccgt ctctactaaa aagataaaaa attagccagg tgtggtggtg cacacctgta     4080

atcccagcta cttgggag                                                   4098


<210>  2559
<211>  4468
<212>  DNA
<213>  homo sapiens

<400>  2559
agcaaatcag atatgcccaa aacgttacag aggtaacagt gaatccagga tgctgctgtc       60

agcctgtgca ttgtgaagaa ggcaatcata ggcgagcagc cgcgggagca ggaacagcag      120

cgtgctaaga agcagtcaca taaacagcag caggagtagg cctcctgctt ttcaaaagca      180

gagtactgca gggtcgcgaa atgcaagaca ctcagatgtt tgaaaatctc ccgagttgag      240

aatggctact gtaaaagcgt caccaagaaa ctctgacgat ctggacagtc ctaactctgt      300

gttagcaata cttacttccg gaaaattaat gctacttctt gtagattttt gcaaatagga      360

aacccccttg aagaagatct caaattacgc cccccacccc caaaaaaaga caaacagggg      420

agaacaaagt tttggcatgc ctgcaggaac ggtggctttt ttagaaacta cctaggaggc      480

agaagctaag tgatttgctc atgcctctta cctgggagta gaaggtggga agaaatggac      540

cgaggctgtg acgagaagac aaggcacagt gcagcttggt gaagccacac gctgactgcg      600

ttctgccccc tcttcatgca gtgctgcggg ctggtgcatc gccggcgagt acgggtgtcc      660

tatggttcgg cagactccta cactagccgt ccatccgatt ccgatgtatc tctggaggag      720

gaccgggagg cagtgcgcag agaagcggag cggcaggccc aggcacagtt ggaaaaagca      780

aagacaaagc ccgttgcatt tgcggttcgg acaaatgtca gctacagtgc ggcccatgaa      840

gatgatgttc cagtgcctgg catggccatc tcattcgaag caaaagattt tctgcatgtt      900

aaggaaaaat ttaacaatga ctggtggata gggcgattgg taaaagaagg ctgtgaaatc      960

ggattcattc caagcccagt caaactagaa aacatgaggc tgcagcatga acagagagcc     1020

aagcaaggga aattctactc cagtaaatca ggaggaaatt catcatccag tttgggtgac     1080

atagtaccta gttccagaaa atcaacacct ccatcatctg ctatagacat agatgctact     1140

ggcttagatg cagaagaaaa tgatattcca gcaaaccacc gctcccctaa acccagtgca     1200

aacagtgtaa cgtcacccca ctccaaagag aaaagaatgc ccttctttaa gaagacagag     1260

cacactcctc cgtatgatgt ggtaccttcc atgcgaccag tggtcctagt gggcccttct     1320

ctgaagggct acgaggtcac agatatgatg caaaaagcgc tgtttgattt tttaaaacac     1380

agatttgaag ggcggatatc catcacaagg gtcaccgctg acatctcgct tgccaaacgc     1440

tcggtattaa acaatcccag taagcacgca ataatagaaa gatccaacac aaggtcaagc     1500

ttagcggaag ttcagagtga aatcgaaagg atttttgaac ttgcaagaac attgcagttg     1560

gtggtccttg acgcggatac aattaatcat ccagctcaac tcagtaaaac ctccttggcc     1620

cctattatag tatatgtaaa gatttcttct cctaaggttt tacaaaggtt aataaaatct     1680

cgagggaaat ctcaagctaa acacctcaac gtccagatgg tagcagctga taaactggct     1740

cagtgtcctc cagagctgtt cgatgtgatc ttggatgaga accagcttga ggatgcctgt     1800

gagcaccttg ccgactatct ggaggcctac tggaaggcca cccatcctcc cagcagtagc     1860

ctccccaacc ctctccttag ccgtacatta gccacttcaa gtctgcctct tagccccacc     1920

ctagcctcta attcacaggg ttctcaaggt gatcagagga ctgatcgctc cgctcctatc     1980

cgttctgctt cccaagctga agaagaacct agtgtggaac cagtcaagaa atcccagcac     2040

cgctcttcct cctcagcccc acaccacaac catcgcagtg ggacaagtcg cggcctctcc     2100

aggcaagaga catttgactc ggaaacccag gagagtcgag actctgccta cgtagagcca     2160

aaggaagatt attcccatga ccacgtggac cactatgcct cacaccgtga ccacaaccac     2220

agagacgaga cccacgggag cagtgaccac agacacaggg agtcccggca ccgttcccgg     2280

gacgtggatc gagagcagga ccacaacgag tgcaacaagc agcgcagccg tcataaatcc     2340

aaggatcgct actgtgaaaa ggatggagaa gtgatatcaa aaaaacggaa tgaggctggg     2400

gagtggaaca gggatgttta catccgccaa tgagttttgc ccgtttgtgt tttttttttt     2460

ttttttttga agtcttgtat aactaacagc atccccaaaa caaagtcttt ggggtctaca     2520

ctgcaatcat atgtgatctg tcttgtaata ttttgtatta ttgctgttgc ttgaatagca     2580

atagcatgga tagagtattg agatactttt tcttttgtaa gtgctacata aattggcctg     2640

gtatggctgc agtcctccgg ttgcatactg gactcttcaa aaactgtttt gggtagctgc     2700

cacttgaaca aaatctgttg ccacccaggt gatgttagtg ttttaagaaa tgtagttgat     2760

gtatccaaca agccagaatc agcacagata aaaagtggaa tttcttgttt ctccagattt     2820

ttaatacgtt aatacgcagg catctgattt gcatattcat tcatggacca ctgtttcttg     2880

cttgtacctc tggctgacta aatttgggga cagattcagt cttgccttac acaaagggga     2940

tcataaagtt agaatctatt ttctatgtac tagtactgtg tactgtatag acagtttgta     3000

aatgttattt ctgcaaacaa acaccttctt attatatata taatatatat atatatcagt     3060

ttgatcacac tattttagag tcttaatgcc aagtcagcag atttgcttta tgaattacag     3120

ggactagaaa tgcccacatt caggaaattt gtaataacat tgtctagaca cctatcctca     3180

ttctagtaga aagtgtgtac atactgtaaa tatgtgtgat tgcttgactt gaaaaggttt     3240

gaattctgaa tgttatacca tccttgtaag taagtttgta atttccacca taaattatgg     3300

taaatataaa actccagagg ttgttctact ccatacagtt cacactgatt gtgacacatt     3360

cttagtagct agtgtctgtt ctagtcactg cactggagtc tacgagccgg aactcgctat     3420

atgcacgtgt gtgtgtccgt atgtaagaaa gtgtgcaccg agtgactgaa tggttgagat     3480

gaattggaat gctgaagact aacgaagaaa ctagagactg atatcgagca ttctgcccac     3540

ctcgctctgt atttaattaa ttgtgctata tgttgcttta acaacccatt gagcagtcag     3600

ggaatgtgag taagcttgct gccaaaggta actaggaaag cattcatctg ctgcctcctt     3660

gtttttgctc ctagagagtg aaaatacagg caattttact gtgagtgttt cactggaaat     3720

gtacaatctt tgtgtgttag agtatttgtt ttagtaagaa atgtttacac agcttgtgga     3780

attatttcgt gggaaaataa atttttataa cttctcccac ttcaatttct aaccttgcct     3840

attgttcctg ttgtttgttt acctcccagt tacctaccat tcctccccac caccgactcc     3900

agcaggttca ctgtctgtca gaacccagaa gtgcttctta taaccaaagt ttctgttctt     3960

cagaagaaat cagggcaaaa tggggtgact tgaagtgaat aaaatgttaa gaatattatc     4020

ctacataaga catgtacaca gaaggggaac cttgaagaca ttatctccat gcctcaatta     4080

cactgctgta agaagcttac aatgtcatca tgtttaaggc taagaccttt tccgtgtctc     4140

aagtgtatat tttgtccagt tataactgga tggtaagaca gtattaagag tgcaagtacc     4200

tggcacttga agtttgtccc aggaaaatgc ctgtgtataa ttacctaact tcagatctgc     4260

acattaactt atttaacaaa ataaatcagc cgggcgcagt ggctcatgcc tgtaatccca     4320

gcaatttggg aggctgagga gggtggatca cctgaggtca ggagttcaag accagcctgg     4380

ccaacgtggc gaaaccccgt ctctactaaa aagataaaaa attagccagg tgtggtggtg     4440

cacacctgta atcccagcta cttgggag                                        4468


<210>  2560
<211>  2873
<212>  DNA
<213>  homo sapiens

<400>  2560
ccttgctctc gccgctgctg ccggagccga agcagagaag gcagcgggtc ccgtgaccgt       60

cccgagagcc ccgcgctccc gaccaggggg cgggggcggc cccggggagg gcggggcagg      120

ggcgggggga agaaaggggg ttttgtgctg cgccgggagg gccggcgccc tcttccgaat      180

gtcctgcggc cccagcctct cctcacgctc gcgcagtctc cgccgcagtc tcagctgcag      240

ctgcaggact gagccgtgca cccggaggag acccccggag gaggcgacaa acttcgcagt      300

gccgcgaccc aaccccagcc ctgggtagcc tgcagcatgg cccagctgtt cctgcccctg      360

ctggcagccc tggtcctggc ccaggctcct gcagctttag cagatgttct ggaaggagac      420

agctcagagg accgcgcttt tcgcgtgcgc atcgcgggcg acgcgccact gcagggcgtg      480

ctcggcggcg ccctcaccat cccttgccac gtccactacc tgcggccacc gccgagccgc      540

cgggctgtgc tgggctctcc gcgggtcaag tggactttcc tgtcccgggg ccgggaggca      600

gaggtgctgg tggcgcgggg agtgcgcgtc aaggtgaacg aggcctaccg gttccgcgtg      660

gcactgcctg cgtacccagc gtcgctcacc gacgtctccc tggcgctgag cgagctgcgc      720

cccaacgact caggtatcta tcgctgtgag gtccagcacg gcatcgatga cagcagcgac      780

gctgtggagg tcaaggtcaa aggggtcgtc tttctctacc gagagggctc tgcccgctat      840

gctttctcct tttctggggc ccaggaggcc tgtgcccgca ttggagccca catcgccacc      900

ccggagcagc tctatgccgc ctaccttggg ggctatgagc aatgtgatgc tggctggctg      960

tcggatcaga ccgtgaggta tcccatccag accccacgag aggcctgtta cggagacatg     1020

gatggcttcc ccggggtccg gaactatggt gtggtggacc cggatgacct ctatgatgtg     1080

tactgttatg ctgaagacct aaatggagaa ctgttcctgg gtgaccctcc agagaagctg     1140

acattggagg aagcacgggc gtactgccag gagcggggtg cagagattgc caccacgggc     1200

caactgtatg cagcctggga tggtggcctg gaccactgca gcccagggtg gctagctgat     1260

ggcagtgtgc gctaccccat cgtcacaccc agccagcgct gtggtggggg cttgcctggt     1320

gtcaagactc tcttcctctt ccccaaccag actggcttcc ccaataagca cagccgcttc     1380

aacgtctact gcttccgaga ctcggcccag ccttctgcca tccctgaggc ctccaaccca     1440

gcctccaacc cagcctctga tggactagag gctatcgtca cagtgacaga gaccctggag     1500

gaactgcagc tgcctcagga agccacagag agtgaatccc gtggggccat ctactccatc     1560

cccatcatgg aggacggagg aggtggaagc tccactccag aagacccagc agaggcccct     1620

aggacgctcc tagaatttga aacacaatcc atggtaccgc ccacggggtt ctcagaagag     1680

gaaggtaagg cattggagga agaagagaaa tatgaagatg aagaagagaa agaggaggaa     1740

gaagaagagg aggaggtgga ggatgaggct ctgtgggcat ggcccagcga gctcagcagc     1800

ccgggccctg aggcctctct ccccactgag ccagcagccc aggaggagtc actctcccag     1860

gcgccagcaa gggcagtcct gcagcctggt gcatcaccac ttcctgatgg agagtcagaa     1920

gcttccaggc ctccaagggt ccatggacca cctactgaga ctctgcccac tcccagggag     1980

aggaacctag catccccatc accttccact ctggttgagg caagagaggt gggggaggca     2040

actggtggtc ctgagctatc tggggtccct cgaggagaga gcgaggagac aggaagctcc     2100

gagggtgccc cttccctgct tccagccaca cgggcccctg agggtaccag ggagctggag     2160

gccccctctg aagataattc tggaagaact gccccagcag ggacctcagt gcaggcccag     2220

ccagtgctgc ccactgacag cgccagccga ggtggagtgg ccgtggtccc cgcatcaggt     2280

aattctgccc aaggctcaac tgccctctct atcctactcc ttttcttccc cctgcagctc     2340

tgggtcacct gacctgtagt cctttaaccc accatcatcc caaactctcc tgtcctttgc     2400

cttcattctc ttacccacct ctacctatgg gtctccaatc tcggatatcc accttgtggg     2460

tatctcagct ctccgcgtct ttaccctgtg atcccagccc cgccactgac catctgtgac     2520

ccttccctgc cattgggccc tccacctgtg gctcacatct cgccagcccc acagagcatc     2580

ctcaggcctc tccaagggtc ctcatcacct attgcagcct tcagggctcg gcctattttc     2640

cactactccc ttcatccgcc tgtgtgccgt cccctttagc tgcctcctat tgatctcagg     2700

gaagcctggg agtcccttct cacccctcaa cctccggagt ccaggagaac ccgtaccccc     2760

acagagcctt aagcaactac ttctgtgaag tattttttga ctgtttcatg gaaaacaagc     2820

cttggaaata aatctctatt aaaccgcttt gtaaccaaaa aaaaaaaaaa aaa            2873


<210>  2561
<211>  3470
<212>  DNA
<213>  homo sapiens

<400>  2561
ccttgctctc gccgctgctg ccggagccga agcagagaag gcagcgggtc ccgtgaccgt       60

cccgagagcc ccgcgctccc gaccaggggg cgggggcggc cccggggagg gcggggcagg      120

ggcgggggga agaaaggggg ttttgtgctg cgccgggagg gccggcgccc tcttccgaat      180

gtcctgcggc cccagcctct cctcacgctc gcgcagtctc cgccgcagtc tcagctgcag      240

ctgcaggact gagccgtgca cccggaggag acccccggag gaggcgacaa acttcgcagt      300

gccgcgaccc aaccccagcc ctgggtagcc tgcagcatgg cccagctgtt cctgcccctg      360

ctggcagccc tggtcctggc ccaggctcct gcagctttag cagatgttct ggaaggagac      420

agctcagagg accgcgcttt tcgcgtgcgc atcgcgggcg acgcgccact gcagggcgtg      480

ctcggcggcg ccctcaccat cccttgccac gtccactacc tgcggccacc gccgagccgc      540

cgggctgtgc tgggctctcc gcgggtcaag tggactttcc tgtcccgggg ccgggaggca      600

gaggtgctgg tggcgcgggg agtgcgcgtc aaggtgaacg aggcctaccg gttccgcgtg      660

gcactgcctg cgtacccagc gtcgctcacc gacgtctccc tggcgctgag cgagctgcgc      720

cccaacgact caggtatcta tcgctgtgag gtccagcacg gcatcgatga cagcagcgac      780

gctgtggagg tcaaggtcaa aggggtcgtc tttctctacc gagagggctc tgcccgctat      840

gctttctcct tttctggggc ccaggaggcc tgtgcccgca ttggagccca catcgccacc      900

ccggagcagc tctatgccgc ctaccttggg ggctatgagc aatgtgatgc tggctggctg      960

tcggatcaga ccgtgaggta tcccatccag accccacgag aggcctgtta cggagacatg     1020

gatggcttcc ccggggtccg gaactatggt gtggtggacc cggatgacct ctatgatgtg     1080

tactgttatg ctgaagacct aaatggagaa ctgttcctgg gtgaccctcc agagaagctg     1140

acattggagg aagcacgggc gtactgccag gagcggggtg cagagattgc caccacgggc     1200

caactgtatg cagcctggga tggtggcctg gaccactgca gcccagggtg gctagctgat     1260

ggcagtgtgc gctaccccat cgtcacaccc agccagcgct gtggtggggg cttgcctggt     1320

gtcaagactc tcttcctctt ccccaaccag actggcttcc ccaataagca cagccgcttc     1380

aacgtctact gcttccgaga ctcggcccag ccttctgcca tccctgaggc ctccaaccca     1440

gcctccaacc cagcctctga tggactagag gctatcgtca cagtgacaga gaccctggag     1500

gaactgcagc tgcctcagga agccacagag agtgaatccc gtggggccat ctactccatc     1560

cccatcatgg aggacggagg aggtggaagc tccactccag aagacccagc agaggcccct     1620

aggacgctcc tagaatttga aacacaatcc atggtaccgc ccacggggtt ctcagaagag     1680

gaaggtaagg cattggagga agaagagaaa tatgaagatg aagaagagaa agaggaggaa     1740

gaagaagagg aggaggtgga ggatgaggct ctgtgggcat ggcccagcga gctcagcagc     1800

ccgggccctg aggcctctct ccccactgag ccagcagccc aggaggagtc actctcccag     1860

gcgccagcaa gggcagtcct gcagcctggt gcatcaccac ttcctgatgg agagtcagaa     1920

gcttccaggc ctccaagggt ccatggacca cctactgaga ctctgcccac tcccagggag     1980

aggaacctag catccccatc accttccact ctggttgagg caagagaggt gggggaggca     2040

actggtggtc ctgagctatc tggggtccct cgaggagaga gcgaggagac aggaagctcc     2100

gagggtgccc cttccctgct tccagccaca cgggcccctg agggtaccag ggagctggag     2160

gccccctctg aagataattc tggaagaact gccccagcag ggacctcagt gcaggcccag     2220

ccagtgctgc ccactgacag cgccagccga ggtggagtgg ccgtggtccc cgcatcaggt     2280

gactgtgtcc ccagcccctg ccacaatggt gggacatgct tggaggagga ggaaggggtc     2340

cgctgcctat gtctgcctgg ctatgggggg gacctgtgcg atgttggcct ccgcttctgc     2400

aaccccggct gggacgcctt ccagggcgcc tgctacaagc acttttccac acgaaggagc     2460

tgggaggagg cagagaccca gtgccggatg tacggcgcgc atctggccag catcagcaca     2520

cccgaggaac aggacttcat caacaaccgg taccgggagt accagtggat cggactcaac     2580

gacaggacca tcgaaggcga cttcttgtgg tcggatggcg tccccctgct ctatgagaac     2640

tggaaccctg ggcagcctga cagctacttc ctgtctggag agaactgcgt ggtcatggtg     2700

tggcatgatc agggacaatg gagtgacgtg ccctgcaact accacctgtc ctacacctgc     2760

aagatggggc tggtgtcctg tgggccgcca ccggagctgc ccctggctca agtgttcggc     2820

cgcccacggc tgcgctatga ggtggacact gtgcttcgct accggtgccg ggaaggactg     2880

gcccagcgca atctgccgct gatccgatgc caagagaacg gtcgttggga ggccccccag     2940

atctcctgtg tgcccagaag acctgcccga gctctgcacc cagaggagga cccagaagga     3000

cgtcagggga ggctactggg acgctggaag gcgctgttga tccccccttc cagccccatg     3060

ccaggtccct agggggcaag gccttgaaca ctgccggcca cagcactgcc ctgtcaccca     3120

aattttccct cacaccctgc gctcccgcca ccacaggaag tgacaacatg acgaggggtg     3180

gtactggagt ccaggtgaca gttcctgaag gggcttctgg gaaataccta ggaggctcca     3240

gcccagccca ggccctctcc ccctaccctg ggcaccagat cttccatcag ggccggagta     3300

aatccctaag tgcctcaact gccctctccc tggcagccat cttgtcccct ctattcctct     3360

agggagcact gtgcccactc tttctgggtt ttccaaggga atgggcttgc aggatggagt     3420

gtctgtaaaa tcaacaggaa ataaaactgt gtatgagccc aggcaagttg                3470


<210>  2562
<211>  2873
<212>  DNA
<213>  homo sapiens

<400>  2562
ccttgctctc gccgctgctg ccggagccga agcagagaag gcagcgggtc ccgtgaccgt       60

cccgagagcc ccgcgctccc gaccaggggg cgggggcggc cccggggagg gcggggcagg      120

ggcgggggga agaaaggggg ttttgtgctg cgccgggagg gccggcgccc tcttccgaat      180

gtcctgcggc cccagcctct cctcacgctc gcgcagtctc cgccgcagtc tcagctgcag      240

ctgcaggact gagccgtgca cccggaggag acccccggag gaggcgacaa acttcgcagt      300

gccgcgaccc aaccccagcc ctgggtagcc tgcagcatgg cccagctgtt cctgcccctg      360

ctggcagccc tggtcctggc ccaggctcct gcagctttag cagatgttct ggaaggagac      420

agctcagagg accgcgcttt tcgcgtgcgc atcgcgggcg acgcgccact gcagggcgtg      480

ctcggcggcg ccctcaccat cccttgccac gtccactacc tgcggccacc gccgagccgc      540

cgggctgtgc tgggctctcc gcgggtcaag tggactttcc tgtcccgggg ccgggaggca      600

gaggtgctgg tggcgcgggg agtgcgcgtc aaggtgaacg aggcctaccg gttccgcgtg      660

gcactgcctg cgtacccagc gtcgctcacc gacgtctccc tggcgctgag cgagctgcgc      720

cccaacgact caggtatcta tcgctgtgag gtccagcacg gcatcgatga cagcagcgac      780

gctgtggagg tcaaggtcaa aggggtcgtc tttctctacc gagagggctc tgcccgctat      840

gctttctcct tttctggggc ccaggaggcc tgtgcccgca ttggagccca catcgccacc      900

ccggagcagc tctatgccgc ctaccttggg ggctatgagc aatgtgatgc tggctggctg      960

tcggatcaga ccgtgaggta tcccatccag accccacgag aggcctgtta cggagacatg     1020

gatggcttcc ccggggtccg gaactatggt gtggtggacc cggatgacct ctatgatgtg     1080

tactgttatg ctgaagacct aaatggagaa ctgttcctgg gtgaccctcc agagaagctg     1140

acattggagg aagcacgggc gtactgccag gagcggggtg cagagattgc caccacgggc     1200

caactgtatg cagcctggga tggtggcctg gaccactgca gcccagggtg gctagctgat     1260

ggcagtgtgc gctaccccat cgtcacaccc agccagcgct gtggtggggg cttgcctggt     1320

gtcaagactc tcttcctctt ccccaaccag actggcttcc ccaataagca cagccgcttc     1380

aacgtctact gcttccgaga ctcggcccag ccttctgcca tccctgaggc ctccaaccca     1440

gcctccaacc cagcctctga tggactagag gctatcgtca cagtgacaga gaccctggag     1500

gaactgcagc tgcctcagga agccacagag agtgaatccc gtggggccat ctactccatc     1560

cccatcatgg aggacggagg aggtggaagc tccactccag aagacccagc agaggcccct     1620

aggacgctcc tagaatttga aacacaatcc atggtaccgc ccacggggtt ctcagaagag     1680

gaaggtaagg cattggagga agaagagaaa tatgaagatg aagaagagaa agaggaggaa     1740

gaagaagagg aggaggtgga ggatgaggct ctgtgggcat ggcccagcga gctcagcagc     1800

ccgggccctg aggcctctct ccccactgag ccagcagccc aggaggagtc actctcccag     1860

gcgccagcaa gggcagtcct gcagcctggt gcatcaccac ttcctgatgg agagtcagaa     1920

gcttccaggc ctccaagggt ccatggacca cctactgaga ctctgcccac tcccagggag     1980

aggaacctag catccccatc accttccact ctggttgagg caagagaggt gggggaggca     2040

actggtggtc ctgagctatc tggggtccct cgaggagaga gcgaggagac aggaagctcc     2100

gagggtgccc cttccctgct tccagccaca cgggcccctg agggtaccag ggagctggag     2160

gccccctctg aagataattc tggaagaact gccccagcag ggacctcagt gcaggcccag     2220

ccagtgctgc ccactgacag cgccagccga ggtggagtgg ccgtggtccc cgcatcaggt     2280

aattctgccc aaggctcaac tgccctctct atcctactcc ttttcttccc cctgcagctc     2340

tgggtcacct gacctgtagt cctttaaccc accatcatcc caaactctcc tgtcctttgc     2400

cttcattctc ttacccacct ctacctatgg gtctccaatc tcggatatcc accttgtggg     2460

tatctcagct ctccgcgtct ttaccctgtg atcccagccc cgccactgac catctgtgac     2520

ccttccctgc cattgggccc tccacctgtg gctcacatct cgccagcccc acagagcatc     2580

ctcaggcctc tccaagggtc ctcatcacct attgcagcct tcagggctcg gcctattttc     2640

cactactccc ttcatccgcc tgtgtgccgt cccctttagc tgcctcctat tgatctcagg     2700

gaagcctggg agtcccttct cacccctcaa cctccggagt ccaggagaac ccgtaccccc     2760

acagagcctt aagcaactac ttctgtgaag tattttttga ctgtttcatg gaaaacaagc     2820

cttggaaata aatctctatt aaaccgcttt gtaaccaaaa aaaaaaaaaa aaa            2873


<210>  2563
<211>  3470
<212>  DNA
<213>  homo sapiens

<400>  2563
ccttgctctc gccgctgctg ccggagccga agcagagaag gcagcgggtc ccgtgaccgt       60

cccgagagcc ccgcgctccc gaccaggggg cgggggcggc cccggggagg gcggggcagg      120

ggcgggggga agaaaggggg ttttgtgctg cgccgggagg gccggcgccc tcttccgaat      180

gtcctgcggc cccagcctct cctcacgctc gcgcagtctc cgccgcagtc tcagctgcag      240

ctgcaggact gagccgtgca cccggaggag acccccggag gaggcgacaa acttcgcagt      300

gccgcgaccc aaccccagcc ctgggtagcc tgcagcatgg cccagctgtt cctgcccctg      360

ctggcagccc tggtcctggc ccaggctcct gcagctttag cagatgttct ggaaggagac      420

agctcagagg accgcgcttt tcgcgtgcgc atcgcgggcg acgcgccact gcagggcgtg      480

ctcggcggcg ccctcaccat cccttgccac gtccactacc tgcggccacc gccgagccgc      540

cgggctgtgc tgggctctcc gcgggtcaag tggactttcc tgtcccgggg ccgggaggca      600

gaggtgctgg tggcgcgggg agtgcgcgtc aaggtgaacg aggcctaccg gttccgcgtg      660

gcactgcctg cgtacccagc gtcgctcacc gacgtctccc tggcgctgag cgagctgcgc      720

cccaacgact caggtatcta tcgctgtgag gtccagcacg gcatcgatga cagcagcgac      780

gctgtggagg tcaaggtcaa aggggtcgtc tttctctacc gagagggctc tgcccgctat      840

gctttctcct tttctggggc ccaggaggcc tgtgcccgca ttggagccca catcgccacc      900

ccggagcagc tctatgccgc ctaccttggg ggctatgagc aatgtgatgc tggctggctg      960

tcggatcaga ccgtgaggta tcccatccag accccacgag aggcctgtta cggagacatg     1020

gatggcttcc ccggggtccg gaactatggt gtggtggacc cggatgacct ctatgatgtg     1080

tactgttatg ctgaagacct aaatggagaa ctgttcctgg gtgaccctcc agagaagctg     1140

acattggagg aagcacgggc gtactgccag gagcggggtg cagagattgc caccacgggc     1200

caactgtatg cagcctggga tggtggcctg gaccactgca gcccagggtg gctagctgat     1260

ggcagtgtgc gctaccccat cgtcacaccc agccagcgct gtggtggggg cttgcctggt     1320

gtcaagactc tcttcctctt ccccaaccag actggcttcc ccaataagca cagccgcttc     1380

aacgtctact gcttccgaga ctcggcccag ccttctgcca tccctgaggc ctccaaccca     1440

gcctccaacc cagcctctga tggactagag gctatcgtca cagtgacaga gaccctggag     1500

gaactgcagc tgcctcagga agccacagag agtgaatccc gtggggccat ctactccatc     1560

cccatcatgg aggacggagg aggtggaagc tccactccag aagacccagc agaggcccct     1620

aggacgctcc tagaatttga aacacaatcc atggtaccgc ccacggggtt ctcagaagag     1680

gaaggtaagg cattggagga agaagagaaa tatgaagatg aagaagagaa agaggaggaa     1740

gaagaagagg aggaggtgga ggatgaggct ctgtgggcat ggcccagcga gctcagcagc     1800

ccgggccctg aggcctctct ccccactgag ccagcagccc aggaggagtc actctcccag     1860

gcgccagcaa gggcagtcct gcagcctggt gcatcaccac ttcctgatgg agagtcagaa     1920

gcttccaggc ctccaagggt ccatggacca cctactgaga ctctgcccac tcccagggag     1980

aggaacctag catccccatc accttccact ctggttgagg caagagaggt gggggaggca     2040

actggtggtc ctgagctatc tggggtccct cgaggagaga gcgaggagac aggaagctcc     2100

gagggtgccc cttccctgct tccagccaca cgggcccctg agggtaccag ggagctggag     2160

gccccctctg aagataattc tggaagaact gccccagcag ggacctcagt gcaggcccag     2220

ccagtgctgc ccactgacag cgccagccga ggtggagtgg ccgtggtccc cgcatcaggt     2280

gactgtgtcc ccagcccctg ccacaatggt gggacatgct tggaggagga ggaaggggtc     2340

cgctgcctat gtctgcctgg ctatgggggg gacctgtgcg atgttggcct ccgcttctgc     2400

aaccccggct gggacgcctt ccagggcgcc tgctacaagc acttttccac acgaaggagc     2460

tgggaggagg cagagaccca gtgccggatg tacggcgcgc atctggccag catcagcaca     2520

cccgaggaac aggacttcat caacaaccgg taccgggagt accagtggat cggactcaac     2580

gacaggacca tcgaaggcga cttcttgtgg tcggatggcg tccccctgct ctatgagaac     2640

tggaaccctg ggcagcctga cagctacttc ctgtctggag agaactgcgt ggtcatggtg     2700

tggcatgatc agggacaatg gagtgacgtg ccctgcaact accacctgtc ctacacctgc     2760

aagatggggc tggtgtcctg tgggccgcca ccggagctgc ccctggctca agtgttcggc     2820

cgcccacggc tgcgctatga ggtggacact gtgcttcgct accggtgccg ggaaggactg     2880

gcccagcgca atctgccgct gatccgatgc caagagaacg gtcgttggga ggccccccag     2940

atctcctgtg tgcccagaag acctgcccga gctctgcacc cagaggagga cccagaagga     3000

cgtcagggga ggctactggg acgctggaag gcgctgttga tccccccttc cagccccatg     3060

ccaggtccct agggggcaag gccttgaaca ctgccggcca cagcactgcc ctgtcaccca     3120

aattttccct cacaccctgc gctcccgcca ccacaggaag tgacaacatg acgaggggtg     3180

gtactggagt ccaggtgaca gttcctgaag gggcttctgg gaaataccta ggaggctcca     3240

gcccagccca ggccctctcc ccctaccctg ggcaccagat cttccatcag ggccggagta     3300

aatccctaag tgcctcaact gccctctccc tggcagccat cttgtcccct ctattcctct     3360

agggagcact gtgcccactc tttctgggtt ttccaaggga atgggcttgc aggatggagt     3420

gtctgtaaaa tcaacaggaa ataaaactgt gtatgagccc aggcaagttg                3470


<210>  2564
<211>  8169
<212>  DNA
<213>  homo sapiens

<400>  2564
acagccgggc tggagcgcgc acccggcact gaggcttcgc tgctctcgga gcgctcagac       60

cgcggccgcc gcagccggcg aaagaggcaa agtcccgcac gccggaggac atgcgcctcg      120

gctagcggcc ccgggcccca ccaccgtgcg gctttctcca gattattcct ctctcgctgt      180

ctctgactgt ctctctctgt ctctgtctct gtctctctct ctctcacaca cacacacaca      240

cacacaaaca cacatacgca cgcacgatct cacttcgatc tatacactgg aggattaaaa      300

caaacaaaca aaaaaaacat ttccttcgct ccccctccct ctccactctg agaagcagag      360

gagccgcacg gcgaggggcc gcagaccgtc tggaaatgcg aatcctaaag cgtttcctcg      420

cttgcattca gctcctctgt gtttgccgcc tggattgggc taatggatac tacagacaac      480

agagaaaact tgttgaagag attggctggt cctatacagg agcactgaat caaaaaaatt      540

ggggaaagaa atatccaaca tgtaatagcc caaaacaatc tcctatcaat attgatgaag      600

atcttacaca agtaaatgtg aatcttaaga aacttaaatt tcagggttgg gataaaacat      660

cattggaaaa cacattcatt cataacactg ggaaaacagt ggaaattaat ctcactaatg      720

actaccgtgt cagcggagga gtttcagaaa tggtgtttaa agcaagcaag ataacttttc      780

actggggaaa atgcaatatg tcatctgatg gatcagagca tagtttagaa ggacaaaaat      840

ttccacttga gatgcaaatc tactgctttg atgcggaccg attttcaagt tttgaggaag      900

cagtcaaagg aaaagggaag ttaagagctt tatccatttt gtttgaggtt gggacagaag      960

aaaatttgga tttcaaagcg attattgatg gagtcgaaag tgttagtcgt tttgggaagc     1020

aggctgcttt agatccattc atactgttga accttctgcc aaactcaact gacaagtatt     1080

acatttacaa tggctcattg acatctcctc cctgcacaga cacagttgac tggattgttt     1140

ttaaagatac agttagcatc tctgaaagcc agttggctgt tttttgtgaa gttcttacaa     1200

tgcaacaatc tggttatgtc atgctgatgg actacttaca aaacaatttt cgagagcaac     1260

agtacaagtt ctctagacag gtgttttcct catacactgg aaaggaagag attcatgaag     1320

cagtttgtag ttcagaacca gaaaatgttc aggctgaccc agagaattat accagccttc     1380

ttgttacatg ggaaagacct cgagtcgttt atgataccat gattgagaag tttgcagttt     1440

tgtaccagca gttggatgga gaggaccaaa ccaagcatga atttttgaca gatggctatc     1500

aagacttggg tgctattctc aataatttgc tacccaatat gagttatgtt cttcagatag     1560

tagccatatg cactaatggc ttatatggaa aatacagcga ccaactgatt gtcgacatgc     1620

ctactgataa tcctgaactt gatcttttcc ctgaattaat tggaactgaa gaaataatca     1680

aggaggagga agagggaaaa gacattgaag aaggcgctat tgtgaatcct ggtagagaca     1740

gtgctacaaa ccaaatcagg aaaaaggaac cccagatttc taccacaaca cactacaatc     1800

gcatagggac gaaatacaat gaagccaaga ctaaccgatc cccaacaaga ggaagtgaat     1860

tctctggaaa gggtgatgtt cccaatacat ctttaaattc cacttcccaa ccagtcacta     1920

aattagccac agaaaaagat atttccttga cttctcagac tgtgactgaa ctgccacctc     1980

acactgtgga aggtacttca gcctctttaa atgatggctc taaaactgtt cttagatctc     2040

cacatatgaa cttgtcgggg actgcagaat ccttaaatac agtttctata acagaatatg     2100

aggaggagag tttattgacc agtttcaagc ttgatactgg agctgaagat tcttcaggct     2160

ccagtcccgc aacttctgct atcccattca tctctgagaa catatcccaa gggtatatat     2220

tttcctccga aaacccagag acaataacat atgatgtcct tataccagaa tctgctagaa     2280

atgcttccga agattcaact tcatcaggtt cagaagaatc actaaaggat ccttctatgg     2340

agggaaatgt gtggtttcct agctctacag acataacagc acagcccgat gttggatcag     2400

gcagagagag ctttctccag actaattaca ctgagatacg tgttgatgaa tctgagaaga     2460

caaccaagtc cttttctgca ggcccagtga tgtcacaggg tccctcagtt acagatctgg     2520

aaatgccaca ttattctacc tttgcctact tcccaactga ggtaacacct catgctttta     2580

ccccatcctc cagacaacag gatttggtct ccacggtcaa cgtggtatac tcgcagacaa     2640

cccaaccggt atacaatggt gagacacctc ttcaaccttc ctacagtagt gaagtctttc     2700

ctctagtcac ccctttgttg cttgacaatc agatcctcaa cactacccct gctgcttcaa     2760

gtagtgattc ggccttgcat gctacgcctg tatttcccag tgtcgatgtg tcatttgaat     2820

ccatcctgtc ttcctatgat ggtgcacctt tgcttccatt ttcctctgct tccttcagta     2880

gtgaattgtt tcgccatctg catacagttt ctcaaatcct tccacaagtt acttcagcta     2940

ccgagagtga taaggtgccc ttgcatgctt ctctgccagt ggctgggggt gatttgctat     3000

tagagcccag ccttgctcag tattctgatg tgctgtccac tactcatgct gcttcagaga     3060

cgctggaatt tggtagtgaa tctggtgttc tttataaaac gcttatgttt tctcaagttg     3120

aaccacccag cagtgatgcc atgatgcatg cacgttcttc agggcctgaa ccttcttatg     3180

ccttgtctga taatgagggc tcccaacaca tcttcactgt ttcttacagt tctgcaatac     3240

ctgtgcatga ttctgtgggt gtaacttatc agggttcctt atttagcggc cctagccata     3300

taccaatacc taagtcttcg ttaataaccc caactgcatc attactgcag cctactcatg     3360

ccctctctgg tgatggggaa tggtctggag cctcttctga tagtgaattt cttttacctg     3420

acacagatgg gctgacagcc cttaacattt cttcacctgt ttctgtagct gaatttacat     3480

atacaacatc tgtgtttggt gatgataata aggcgctttc taaaagtgaa ataatatatg     3540

gaaatgagac tgaactgcaa attccttctt tcaatgagat ggtttaccct tctgaaagca     3600

cagtcatgcc caacatgtat gataatgtaa ataagttgaa tgcgtcttta caagaaacct     3660

ctgtttccat ttctagcacc aagggcatgt ttccagggtc ccttgctcat accaccacta     3720

aggtttttga tcatgagatt agtcaagttc cagaaaataa cttttcagtt caacctacac     3780

atactgtctc tcaagcatct ggtgacactt cgcttaaacc tgtgcttagt gcaaactcag     3840

agccagcatc ctctgaccct gcttctagtg aaatgttatc tccttcaact cagctcttat     3900

tttatgagac ctcagcttct tttagtactg aagtattgct acaaccttcc tttcaggctt     3960

ctgatgttga caccttgctt aaaactgttc ttccagctgt gcccagtgat ccaatattgg     4020

ttgaaacccc caaagttgat aaaattagtt ctacaatgtt gcatctcatt gtatcaaatt     4080

ctgcttcaag tgaaaacatg ctgcactcta catctgtacc agtttttgat gtgtcgccta     4140

cttctcatat gcactctgct tcacttcaag gtttgaccat ttcctatgca agtgagaaat     4200

atgaaccagt tttgttaaaa agtgaaagtt cccaccaagt ggtaccttct ttgtacagta     4260

atgatgagtt gttccaaacg gccaatttgg agattaacca ggcccatccc ccaaaaggaa     4320

ggcatgtatt tgctacacct gttttatcaa ttgatgaacc attaaataca ctaataaata     4380

agcttataca ttccgatgaa attttaacct ccaccaaaag ttctgttact ggtaaggtat     4440

ttgctggtat tccaacagtt gcttctgata catttgtatc tactgatcat tctgttccta     4500

taggaaatgg gcatgttgcc attacagctg tttctcccca cagagatggt tctgtaacct     4560

caacaaagtt gctgtttcct tctaaggcaa cttctgagct gagtcatagt gccaaatctg     4620

atgccggttt agtgggtggt ggtgaagatg gtgacactga tgatgatggt gatgatgatg     4680

atgatgacag aggtagtgat ggcttatcca ttcataagtg tatgtcatgc tcatcctata     4740

gagaatcaca ggaaaaggta atgaatgatt cagacaccca cgaaaacagt cttatggatc     4800

agaataatcc aatctcatac tcactatctg agaattctga agaagataat agagtcacaa     4860

gtgtatcctc agacagtcaa actggtatgg acagaagtcc tggtaaatca ccatcagcaa     4920

atgggctatc ccaaaagcac aatgatggaa aagaggaaaa tgacattcag actggtagtg     4980

ctctgcttcc tctcagccct gaatctaaag catgggcagt tctgacaagt gatgaagaaa     5040

gtggatcagg gcaaggtacc tcagatagcc ttaatgagaa tgagacttcc acagatttca     5100

gttttgcaga cactaatgaa aaagatgctg atgggatcct ggcagcaggt gactcagaaa     5160

taactcctgg attcccacag tccccaacat catctgttac tagcgagaac tcagaagtgt     5220

tccacgtttc agaggcagag gccagtaata gtagccatga gtctcgtatt ggtctagctg     5280

aggggttgga atccgagaag aaggcagtta taccccttgt gatcgtgtca gccctgactt     5340

ttatctgtct agtggttctt gtgggtattc tcatctactg gaggaaatgc ttccagactg     5400

cacactttta cttagaggac agtacatccc ctagagttat atccacacct ccaacaccta     5460

tctttccaat ttcagatgat gtcggagcaa ttccaataaa gcactttcca aagcatgttg     5520

cagatttaca tgcaagtagt gggtttactg aagaatttga gacactgaaa gagttttacc     5580

aggaagtgca gagctgtact gttgacttag gtattacagc agacagctcc aaccacccag     5640

acaacaagca caagaatcga tacataaata tcgttgccta tgatcatagc agggttaagc     5700

tagcacagct tgctgaaaag gatggcaaac tgactgatta tatcaatgcc aattatgttg     5760

atggctacaa cagaccaaaa gcttatattg ctgcccaagg cccactgaaa tccacagctg     5820

aagatttctg gagaatgata tgggaacata atgtggaagt tattgtcatg ataacaaacc     5880

tcgtggagaa aggaaggaga aaatgtgatc agtactggcc tgccgatggg agtgaggagt     5940

acgggaactt tctggtcact cagaagagtg tgcaagtgct tgcctattat actgtgagga     6000

attttactct aagaaacaca aaaataaaaa agggctccca gaaaggaaga cccagtggac     6060

gtgtggtcac acagtatcac tacacgcagt ggcctgacat gggagtacca gagtactccc     6120

tgccagtgct gacctttgtg agaaaggcag cctatgccaa gcgccatgca gtggggcctg     6180

ttgtcgtcca ctgcagtgct ggagttggaa gaacaggcac atatattgtg ctagacagta     6240

tgttgcagca gattcaacac gaaggaactg tcaacatatt tggcttctta aaacacatcc     6300

gttcacaaag aaattatttg gtacaaactg aggagcaata tgtcttcatt catgatacac     6360

tggttgaggc catacttagt aaagaaactg aggtgctgga cagtcatatt catgcctatg     6420

ttaatgcact cctcattcct ggaccagcag gcaaaacaaa gctagagaaa caattccagc     6480

tcctgagcca gtcaaatata cagcagagtg actattctgc agccctaaag caatgcaaca     6540

gggaaaagaa tcgaacttct tctatcatcc ctgtggaaag atcaagggtt ggcatttcat     6600

ccctgagtgg agaaggcaca gactacatca atgcctccta tatcatgggc tattaccaga     6660

gcaatgaatt catcattacc cagcaccctc tccttcatac catcaaggat ttctggagga     6720

tgatatggga ccataatgcc caactggtgg ttatgattcc tgatggccaa aacatggcag     6780

aagatgaatt tgtttactgg ccaaataaag atgagcctat aaattgtgag agctttaagg     6840

tcactcttat ggctgaagaa cacaaatgtc tatctaatga ggaaaaactt ataattcagg     6900

actttatctt agaagctaca caggatgatt atgtacttga agtgaggcac tttcagtgtc     6960

ctaaatggcc aaatccagat agccccatta gtaaaacttt tgaacttata agtgttataa     7020

aagaagaagc tgccaatagg gatgggccta tgattgttca tgatgagcat ggaggagtga     7080

cggcaggaac tttctgtgct ctgacaaccc ttatgcacca actagaaaaa gaaaattccg     7140

tggatgttta ccaggtagcc aagatgatca atctgatgag gccaggagtc tttgctgaca     7200

ttgagcagta tcagtttctc tacaaagtga tcctcagcct tgtgagcaca aggcaggaag     7260

agaatccatc cacctctctg gacagtaatg gtgcagcatt gcctgatgga aatatagctg     7320

agagcttaga gtctttagtt taacacagaa aggggtgggg gaactcacat ctgagcattg     7380

ttttcctctt cctaaaatta ggcaggaaaa tcagtctagt tctgttatct gttgatttcc     7440

catcacctga cagtaacttt catgacatag gattctgccg ccaaatttat atcattaaca     7500

atgtgtgcct ttttgcaaga cttgtaattt acttattatg tttgaactaa aatgattgaa     7560

ttttacagta tttctaagaa tggaattgtg gtattttttt ctgtattgat tttaacagaa     7620

aatttcaatt tatagaggtt aggaattcca aactacagaa aatgtttgtt tttagtgtca     7680

aatttttagc tgtatttgta gcaattatca ggtttgctag aaatataact tttaatacag     7740

tagcctgtaa ataaaacact cttccatatg atattcaaca ttttacaact gcagtattca     7800

cctaaagtag aaataatctg ttacttattg taaatactgc cctagtgtct ccatggacca     7860

aatttatatt tataattgta gatttttata ttttactact gagtcaagtt ttctagttct     7920

gtgtaattgt ttagtttaat gacgtagttc attagctggt cttactctac cagttttctg     7980

acattgtatt gtgttaccta agtcattaac tttgtttcag catgtaattt taacttttgt     8040

ggaaaataga aataccttca ttttgaaaga agtttttatg agaataacac cttaccaaac     8100

attgttcaaa tggtttttat ccaaggaatt gcaaaaataa atataaatat tgccattaaa     8160

aaaaaaaaa                                                             8169


<210>  2565
<211>  1699
<212>  DNA
<213>  homo sapiens

<400>  2565
ggccctccct ggaggagaac tgaaacttag ggtggggact gtagaaaggg gcggagagat       60

cagccgccca gccaggagtt aagctgaggt cgtctgagcc ctgcgacagc ctggacagca      120

actcaggatg gcatcaggca gggcacgctg cacccgaaaa ctccggaact gggtggtgga      180

gcaagtggag agtgggcagt ttcccggagt gtgctgggat gatacagcta agaccatgtt      240

ccggattccc tggaaacatg caggcaagca ggacttccgg gaggaccagg atgctgcctt      300

cttcaaggcc tgggcaatat ttaagggaaa gtataaggag ggggacacag gaggtccagc      360

tgtctggaag actcgcctgc gctgtgcact caacaagagt tctgaattta aggaggttcc      420

tgagaggggc cgcatggatg ttgctgagcc ctacaaggtg tatcagttgc tgccaccagg      480

aatcgtctct ggccagccag ggactcagaa agtaccatca aagcgacagc acagttctgt      540

gtcctctgag aggaaggagg aagaggatgc catgcagaac tgcacactca gtccctctgt      600

gctccaggac tccctcaata atgaggagga gggggccagt gggggagcag tccattcaga      660

cattgggagc agcagcagca gcagcagccc tgagccacag gaagttacag acacaactga      720

ggcccccttt caaggggatc agaggtccct ggagtttctg cttcctccag agccagacta      780

ctcactgctg ctcaccttca tctacaacgg gcgcgtggtg ggcgaggccc aggtgcaaag      840

cctggattgc cgccttgtgg ctgagccctc aggctctgag agcagcatgg agcaggtgct      900

gttccccaag cctggcccac tggagcccac gcagcgcctg ctgagccagc ttgagagggg      960

catcctagtg gccagcaacc cccgaggcct cttcgtgcag cgcctttgcc ccatccccat     1020

ctcctggaat gcaccccagg ctccacctgg gccaggcccg catctgctgc ccagcaacga     1080

gtgcgtggag ctcttcagaa ccgcctactt ctgcagagac ttggtcaggt actttcaggg     1140

cctgggcccc ccaccgaagt tccaggtaac actgaatttc tgggaagaga gccatggctc     1200

cagccatact ccacagaatc ttatcacagt gaagatggag caggcctttg cccgatactt     1260

gctggagcag actccagagc agcaggcagc cattctgtcc ctggtgtaga gcctggggga     1320

cccatcttcc acctcacctc tttgttcttc ctgtctcctt tgaagtagac tcattcttca     1380

cacgattgac ctgtcctctt tgtgataatt ctcagtagtt gtccgtgata atcgtgtcct     1440

gaaaatcctc gcacacactg gctggtggag aactcaaggc taatttttta tccttttttt     1500

tttttaattt tgagatatac gccctctttc atctgtaagg gactaggaaa ttccaaatgg     1560

tgtgaaccca gggggccttt ccctcttccc tgacctccca actctaaagc caagcacttt     1620

atattttcct cttagatatt cactaaggac ttaaaataaa attttattga aagaggaaaa     1680

aaaaaaaaaa aaaaaaaaa                                                  1699


<210>  2566
<211>  2441
<212>  DNA
<213>  homo sapiens

<400>  2566
cttcccccgc ccccgcagtc tctctctctc tctctctcct tcccccaacc ctccctccct       60

cctccccccg ctccttcccc caaccctctc tctctctccc tctgtctccc tccctctctc      120

tctcccgccg cgcccgcctc ccgcccgccc tcgctccctc cactcctctc ccctcccctc      180

cccggcactg cagcaccagc cgtctgcagc tccggccgcc acttgcgcct ctccagcctc      240

cgcaggccca accgccgcca gcaccatggc cagcaccatt tccgcctaca aggagaagat      300

gaaggagctg tcggtgctgt cgctcatctg ctcctgcttc tacacacagc cgcaccccaa      360

taccgtctac cagtacgggg acatggaggt gaagcagctg gacaagcggg cctcaggcca      420

gagcttcgag gtcatcctca agtccccttc tgacctgtcc ccagagagcc ctatgctctc      480

ctccccaccc aagaagaagg acacctccct ggaggagctg caaaagcggc tggaggcagc      540

cgaggagcgg aggaagacgc aggaggcgca ggtgctgaag cagctggcgg agcggcgcga      600

gcacgagcgc gaggtgctgc acaaggcgct ggaggagaat aacaacttca gccgccaggc      660

ggaggagaag ctcaactaca agatggagct cagcaaggag atccgcgagg cacacctggc      720

cgcactgcgc gagcggctgc gcgagaagga gctgcacgcg gccgaggtgc gcaggaacaa      780

ggagcagcga gaagagatgt cgggctaagg gcccgggacg ggcggcgccc atcctgcgac      840

agaacacgtt cgggttttgg ttttgtttcg ttcacctctg tctagatgca acttttgttc      900

ctcctccccc acccccgccc ccagcttcat gcttctcttc cgcactcagc cgccctgccc      960

tgtcctcgtg gtgagtcgct gaccacggct tcccctgcag gagccgccgg gcgtgagacg     1020

cggtccctcg gtgcagacac caggccgggc gcggctgggt cccccggggg ccctgtgaga     1080

gaggtggcgg tgaccgtggt aaacccaggg cggtggcgtg ggatcacggg tccttacgct     1140

gggctgtctg gtcagcacgt gcaggtcagg gcaggtcctc tgagccggcg cccctggcca     1200

gcaggcgagg ctacagtacc tgctgtcttt ccagggggaa ggggctcccc atgagggagg     1260

ggcgacgggg gaggggggtg atggtgcctg ggagcctgcg tgtgcagccg gtgcttgttg     1320

aactggcagg cgggtgggtg ggggctgcag ctttccttaa tgtggttgca caggggtcct     1380

ctgagaccac ctggcgtgag gtggacaccc tgggccttcc tggaagcctg cagttggggg     1440

cctgccctga gtctgctggg gagtgggcat tctctgccag ggacccatga gcaggctgca     1500

tggtctagag gttgtgggca gcatggacag tcccccactc agaagtgcaa gagttccaaa     1560

gagcctctgg cccaggcccc tccccaccag ggctttgcag atgtccttga aagacccacc     1620

ctagagccct ttggagtgct ggcccctcct gtgccctctg ccctggtgga agcggcagcc     1680

acaagtcctc ctcagggagc cccaaggggg attttgtggg accgctgccc acagatccag     1740

gtgttggaag ggcagcgggt aaggttccca agccagcccc aacacccttc ccacttggca     1800

cccagagggg gctgtgggtg gaggcctgac tccaggcctc tcctgcccac accctctggg     1860

ctgagttcct tctttccctt ggacgcccag tgctggcctt ggaggacggt cagctggagg     1920

atggcggtgg gggaggctgt ctttgtacca ctgcagcatc ccccacttct ccacggaagc     1980

cccatcccaa agctgctgcc tggccccttg ctgtaaagtg tgaagggggc ggctgagttc     2040

tcttaggacc cagagccagg gccctcaact tccatcctgc gggaggcctt ggccgggcac     2100

tgccagtgtc ttccagagtc acacccaggg accacgggag gatcctgacc cctgcagggc     2160

tcaggggtca gcagggaccc actgccccat ctccctctcc ccaccaagac agccccagaa     2220

ggagcagcca gctgggatgg gaacccaagg ctgtccacat ctggcttttg tgggactcag     2280

aaagggaagc agaactgagg gctgggatat tcctcatggt ggcagcgctc atagcgaaag     2340

cctactgtaa tatgcaccca tctcatccac gtagtaaagt gaacttaaaa attcaatcaa     2400

atgaacaatt aaataaacac ctgtgtgttt aagacatggt t                         2441


<210>  2567
<211>  3786
<212>  DNA
<213>  homo sapiens

<400>  2567
agcttctgta agagacggag aggcgcagag tgagggcggg tccgcgcgtc ctcagagccc       60

gctggaggct cggagctgct acccgcagac ttctcccgca cagggctcgc aaagagcgtg      120

attccgagag cctgagactg acgcccgacc tggaaaccag agaagacttc cttagccttt      180

cggatcgcac ttgaggctgg aggcatgagt cctgtgaggc gttggggcag cccctgcctt      240

ttccccttgc agctcttcag cctctgctgg gtgctctcag tggcccagag caaaacagtc      300

cgatacagca ccttcgagga ggatgccccc ggcacggtca tcgggaccct ggccgaggac      360

ctgcatatga aagtatcggg tgacacaagc ttccgcctga tgaagcaatt caacagctct      420

ctgctccggg tgcgcgaagg cgacgggcag ctgaccgtcg gggacgccgg cctggaccgc      480

gagcggctgt gtggccaggc cccgcagtgc gtgctggcct tcgatgtggt cagcttctcg      540

caggagcagt tccggctggt gcacgtggag gtagaggtga gggacgtcaa cgaccacgcg      600

ccgcgcttcc ccagggccca gatcccggta gaggtgtccg agggtgcggc agtgggcacg      660

cgcatcccct tggaggtgcc ggtggacgag gacgtgggcg ccaacgggct gcagaccgtg      720

cgcctggccg agccgcacag cccctttcgc gtggagctgc agacgcgagc ggacggcgct      780

cagtgcgcag acctggtgct gctgcaggag ctggaccgcg agagccaggc cgcctacagc      840

ctggagctgg tggcccagga cggcggccgc ccgccgcgct ccgccacggc tgccctcagc      900

gtgcgcgtcc tggatgcgaa tgaccacagc ccggccttcc cgcagggcgc cgtggccgaa      960

gtggagctgg cggaagacgc gcccgtgggc tccctgcttc tcgacctgga cgcagccgac     1020

cccgacgagg gacctaacgg cgacgtggtg ttcgcatttg gcgcccgcac cccgccggag     1080

gcgcgccgcc tctttcggct tgacccgcga tcaggccgcc tcaccctggc cgggcccgtg     1140

gactacgagc gtcaggacac ctacgagctg gacgtgcggg cgcaggaccg cggacccggg     1200

ccccgcgctg ccacctgcaa ggtcatcgtg cgcatccgag acgtcaatga caacgcaccc     1260

gacatcgcca tcaccccgct ggccgcccca ggcgcgccgg caacctcacc cttcgccgct     1320

gccgccgccg ccgctgcact cgggggagcg gacgctagct cgccggcggg agccgggacg     1380

ccggaggctg gtgccacttc gctggtgccg gagggggcgg cgcgcgagag cctggtggcc     1440

ctggtcagca cctcggacag ggactcgggc gccaacgggc aagtgcgctg cgccctctat     1500

gggcacgagc acttccggct gcagccggcc tacgcgggca gctacctggt ggtgaccgcg     1560

gcgtcgctgg accgcgaacg catcgccgag tacaacttga cgctggtggc cgaggatcgc     1620

ggcgcgcccc cgctgcgcac agtgcggccc tacacggtgc gtgtgggcga cgagaacgac     1680

aacgcgccgc tcttcacgcg gccggtctat gaggtgtcgg tgcgcgagaa caacccgcca     1740

ggcgcctacc tggccacggt ggccgcccgc gaccgggacc tgggccgcaa cggccaggtc     1800

acctaccggc tgctggaggc cgaggtgggc cgcgccgggg gcgccgtgtc cacttatgtc     1860

tcggtggacc cagctaccgg agccatctac gcgctgcgca gcttcgacta tgagacgctg     1920

cgccaactcg acgttcgcat ccaagctagc gacggcggct cccctcagct ttccagcagc     1980

gccctagtgc aagtgcgcgt gctggaccag aacgaccatg cgccagtcct ggtgcacccg     2040

gcgccagcca atggctccct agaagtggcg gtgcctgggc gcaccgcaaa ggacacggtt     2100

gtggcccgtg tgcaggcccg ggatgcagac gagggagcca acggggagct ggcgttcgag     2160

ctgcagcagc aggagccgcg cgaagccttc gccatcggcc gccgcacggg ggagatactg     2220

ctcaccggcg acctctcgca ggagccaccc ggtcgcgtgt tcagggcgct cctggtcata     2280

tccgacggcg gccgtccccc gctcaccacc accgcaactg tcagcttcgt ggtaacagca     2340

gggggcgggc gtgggccggc tgcgcctgcc agtgcaggaa gcccggagcg ttcccgcccg     2400

cctggctctc ggctcggggt gtccgggtcg gtgctgcaat gggacacgcc gctgatcgtc     2460

atcatcgtgc tggccgggag ctgcacgctg ctgctggccg ccatcatcgc catcgccacc     2520

acctgcaacc gccgcaagaa ggagccctac ggtgcctccc cgggttttgg aaaggagccg     2580

gcgccccctg tggcggtgtg gaaaggacac tccttcaaca ccatttctgg cagagaagca     2640

gagaagttca gcggcaaaga cagcggtaaa ggggacagtg atttcaacga cagcgattcc     2700

gacatcagcg gggacgctct gaaaaaggat ctcatcaacc acatgcagag tggactgtgg     2760

gcgtgcaccg ctgagtgtaa gatcctgggc cactctgacc gctgctggag cccatcctgc     2820

agcgggccca acgcacatcc atcgcctcac ccaccagccc agatgtcaac cttctgtaag     2880

agcacgtcac tgcctcggga tcctctgcgc agggacaatt actaccaggc ccagctgccc     2940

aagacagtgg ggctgcagag cgtctatgag aaagtactgc acagagacta tgacaggaca     3000

gtcactctgc tctcccctcc ccgtccaggg aggctcccag acctgcagga gattggagta     3060

cccctctacc agtcccctcc tggcaggtac ctgtccccga agaagggagc caatgaaaat     3120

gtgtaatccc atgctgcatg tcttcacaca tatacaggtc actccgagaa gcccctaagt     3180

tattgaccgg tttcagtgtt gtatatataa atatgcaaga tgtgccttac aatgaagttg     3240

ttggaagcta tttccaatca cattggtact gtttggtatt tgcaaacaaa aatgtagtta     3300

atgtaatttt tatgaaatgt gtgcagtatt taatttttct tatgctattg actttgattt     3360

caattgcggc ttgccatttt cttagtgttt ttaacctgta cattgtgtaa tgtaatgttt     3420

gtatataatg aaattttgtt atatttttat ataataaaag ctaaagtgga agttattgcc     3480

aaaggaactg tctgtaagac aaaaaacaaa acatgttgga attacttaat tgaaatttat     3540

ctttcacctg aaacaaccta gtgtttgaga aattttgcct tgccaagtat aacttgtata     3600

tcttgactct gtggtagatt tcaagttcaa tgttatttaa ttacatttgg ttttccgtaa     3660

accgtgtcac ttataagcac agtaataaaa gatttgtcat gtgtttgaag aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaa                                                                3786


<210>  2568
<211>  6404
<212>  DNA
<213>  homo sapiens

<400>  2568
gactaatggc cctaactaag tattaacccc tgccaagaaa agagctactt cctcttgaag       60

taaatgaaga tagtgatgct ttctcttaaa ctttacttat aaaaagcatc aaagggggga      120

atgaagcagg aaatataaaa ggaaaaacaa gtaaagggaa aacaagtcct ttcctgacca      180

gtctgactca ctccaaagtc ctgctggagc tatgataatt atctgcaagg ccaggcaggg      240

gctccgaagg agtgggctcc aggagcaggg atgagaaaaa caagttctcc ttatcagttt      300

ccctgtttga aattctctcc ccataacatt attctttgtt ctgctctcac aactattttt      360

gtaactattt ctgcaagtct gtaaagattt tgtaagttct tgtttttctt tctgtagcat      420

ggcaaggtca caagacatgt ttaagtaagg taggctcatg ttgcaaatcc tgttgtaaaa      480

cctgtcacgg tatgattaac tgcctttgtt ctgcttctgt aagactgctt tctcacctcg      540

caggttttgc gccaaaaacc cgacttgccc ctgcctgatg catgtataaa agtcaagccc      600

tgtctttgtt cagggctcag cctttggatg ttaatccgct gggccagtgg ccacctaaat      660

aaaaccttcc tgttgcaccc agtgatctct ccggcctcct gattcccaca acatataagc      720

attccttttt ctctgcaacc tagcccgcat ctgtcattga ctttttaaca ataggcattc      780

tgactggatg agatggtatc tcactgtggt ttttctctgc atttttctaa taattaacaa      840

cgtgaatttt gttttcatat gcttgtcagc cacatgtatg tcttcttttg aaaagtatct      900

gttcatgttt ttgcttactt tttaattagg tttttggttt tctttttgtt gttgttgttg      960

ttttctgaga tggagtcttg ctgtgtcacc aggatggagt gcagtggcat gatctcgact     1020

cactgcaacc tccacctccc aggttcagat gattcttctg cttcagtctc ctgagtagct     1080

gggatcacag ggaccattga catttatgga tgtggccata gaattctctt tggaggagtg     1140

gcaatgcctg gacactgcac agcagaattt atataggcat gtgatgtgag agaactacag     1200

aaacctggtt ttcttgggtg aaggtattgc tgtctctaag ccagacctga ttacctgtct     1260

ggagcaagga aaagagccct ggaatatgaa gagacatgag atggtagcta aacatttagt     1320

tatgttttat tattttgccc aacacctttg gccagagcag aacataagag attctttcca     1380

gaaagtgacc ctaagaagat atagaaaatg tggatatgag aatttacagt taagaaaagg     1440

ctgtaaaagt gtggttgagt gtaaacagca caaaggagat tatagtggac ttaaccaatg     1500

tttgaaaact accttgagca aaatatttca atgtaataaa tatgtagaag ttttccataa     1560

aatttcaaat tcaaatagac acaagatgag acatactgaa aataaacatt ttaaatgtaa     1620

agaatgtcgc aaaacatttt gcatgctttc acacctaact caacataaaa gaatccaaac     1680

tagagtgaat ttctacaaat gtgaagcata tggaagagcc tttaactggt cctcaaccct     1740

taataaacat aagagaattc atactggaga aaaaccttac aaatgtaaag aatgtggcaa     1800

agcctttaac cagacctcac accttattag acataagaga attcatactg aagagaaacc     1860

ctacaaatgt gaagaatgtg gcaaagcctt taaccagtca tcgaccctta ctacacataa     1920

tataattcat actggggaaa ttccctacaa atgtgagaaa tgtgttagag cttttaacca     1980

agcctcaaag cttactgaac ataagttaat tcataccgga gagaaacgtt atgaatgtga     2040

agaatgcggc aaagctttta accgatcctc aaaacttact gaacataagt acattcatac     2100

tggagagaag ctgtacaaat gtgaagaatg tggtaaagcc tttaaccagt cctcaaccct     2160

tactacacat aagagaattc atagtggaga gaagccctac aaatgtgaag aatgtggcaa     2220

agcttttaaa caattttcaa atcttactga ccataaaaaa attcatactg gagagaaacc     2280

ctacaaatgt gaggaatgtg gcaaagcttt taaccaactc tcaaacctta ctagacataa     2340

ggtaattcat actggagaga aaccctacaa atgtggagaa tgtggcaaag cctttaacca     2400

gtcctcagcc cttaatacac ataagataat ccatactgga gagaatcccc acaaatgtag     2460

agaatctggc aaagttttcc acctatcctc aaaacttagt acatgtaaga aaattcatac     2520

tggagagaaa ctctacaaat gtgaagaatg tggcaaagcc tttaaccgat cttcaaccct     2580

tattggacat aagagaattc atactggaga gaaaccctac aaatgtgaag aatgtggcaa     2640

agcttttaac caatcttcaa cacttactac acataagata attcatactg aagagaaaca     2700

gtacaaatgt gatgaatgtg gcaaagcttc tacctgatcc tcaaaactca ttgaacacaa     2760

gaaaattcat actggagaga aaccttacaa gtgtgaagaa tgtggcaaaa cttctaacca     2820

tttctcaacc cttactaaac ataagatgat tcatactgga gagaagttac acaaatgtga     2880

tgaatgtgac aaagctttta accaatcttc aaccctttct acacataaaa gaattcatac     2940

tggagagaaa ccctacaaat gtgaagaatg tggcagagct tttaattgat catcaaacct     3000

tattaaacat aagaaaattc atattggaga gaaaccctac aaatgtgaag aatgtggaaa     3060

agcttttaac cagttctcaa ctcttactac acataaaata attcatactg gagagaaacc     3120

atataaatgt gaagaatgtg gcaaagcttt caacctatac gtaaacctta ctacacataa     3180

gaaaattcat actggagaga aaccctacaa gtgtgaagaa tgtggcaaag cttttagcca     3240

agtgtcaact cttactatac ataaaagaat tcatactgga gagaaaccct acaagtgtga     3300

agaatgtggc aaagctttta accaagtgtc aactcttact atacataaaa gaattcatac     3360

tggagagaaa ccttacaaat gtgaggaatg tggcaaaact ttcagtcgat gctcaaaact     3420

tactacacat aagaaaattc atacaggaga gaaaccttac aaatgtgaaa aatgtgctaa     3480

agcttttagc cagtcttcaa ccctttctac atataagata attcacactg gagagaaatg     3540

ctacaaatgt gaagaatgtg gcaaagtttt taaccgatct tcaaacctta cagaccataa     3600

aaaaattcat acaggagaga aatcctacaa atgtgaagaa tgtgacaagg cctttaacct     3660

gtcctcaacg cttactaaac ataaggtaat tcatactgga gagaaactgt acaaatgtaa     3720

agaatgtggt aaagctttta aacagttctc acaccttgct atacataata taattcatac     3780

tggagagaaa ctctacaaat gtgaagaatg tggcaaagct tttaacttat cctcaaacct     3840

tactgcacat aagaaaaatc gtactggaga gaaaccctac aaatgtgaag aatgtggcaa     3900

agctaaccta tcatcaaccc ttactccaca taagacaatt catatttgag agaaaccctg     3960

caaatgtgaa gaatgtggca atgcttgtaa ctaaatctca aactttacta aacataagaa     4020

aattaatact ggaaacttta caaacctgaa agatgtgaca atgattttga caacaccttc     4080

aaacttttct aaacataaaa taaatcatac tggtgagaaa tcttaaaaat atgaagaatg     4140

gtacaaagcc tttaaatggt tgtcacactt gattgtaggt aagataattt atactggagg     4200

aaactcccag aagtgtgaag aatgtggcaa aacttttaat ttttcacacc ttatagcaca     4260

ggaaagcact tcagaaaaat tgtacaaata taaatgtgga aaagccatta atatctgctt     4320

acatcttact caacattaga gagttagtgc ttaataaaag cattataaaa gcaattagtg     4380

taaaatcaga aaatgaaagt tttttttttt tttttagatg gagtcttgct ctgtcaccca     4440

ggctggagtg cagtggtgtg atcttggctc actgcaacct ctgcctccca ggttcaagca     4500

attctcctgc cttagcctcc agagtagctg agactacagg cacacaccac cacatttggc     4560

taattttttt atttttagta gagactggct atcaccatgt tggccaggct gatcttgaac     4620

tcctgacctc aagtgatcca catgcctctg cctcccaaag tgctgggatt ataggtgtga     4680

gtcactgtgc ctgacaaata taagccttta aagagaagaa ggttttcatt ttgaagacaa     4740

acattaggta cataaagagg gttgtagtgt ctttatttgt atcacagatt ttattgtaca     4800

cattatgtac taaaggaaaa tcctgaagca gtgctcaaac tttgatcaac atcagggagt     4860

ttatattgga gaaaaactgc aaatgtaata tatttggaaa aacatttttc aaaaactact     4920

gcttagaaaa caccagggga tttatactaa aatatatttt tgcagatgca gtaagtataa     4980

aagaaattta atccaaaatt aagtgtgtgt aaatatcaga gaattcacag tagaaatatc     5040

taaggcactg acattttaga cattgaacta atcagtgtgc tgagtacaga aaataatcca     5100

aaattaaagt tggtagataa attatttata tataacttta aaagaggtag aaatattttt     5160

agttataatt acatttaaag tatacttttt tctttgaaaa aattacaaaa tttttaaaaa     5220

gtgaatgatg taattcaact caaattactt catgcttttc attctattgt attcacatgt     5280

gaaagcatgt gatcaattgc tgcttcatca aagatatgag acattctttt ttgttaggtg     5340

ggcaatattt tttacctttt ctatggaaga gtaaagacat tacaatgtag gatgcatgat     5400

aaaaatctaa gtggagaggc tctttgtgtt taatttataa tattgaatga tgtatgaggg     5460

aagtgttcag aggaatattc tgcattctag tgaaaatatc ttttatttta gttaaaatta     5520

aattaaaatt agtagtatat cattttacta actgtacttt tatgtaataa aatgcagcac     5580

atttaaaaaa ttttagatta ttgtgaactt aattttttaa ttaaactttt tttttaacat     5640

gttaagacca attgtgcatt cagtgaagta ttatcatgcc actaacttca acctatccca     5700

ccttactcaa gggtgttggt aaaagatagt aacaatgtac tatttaataa cagagtggac     5760

taacatctct aataatttct cttgccagtg actttaaact aaagaactta attaaagaac     5820

attgttccca taggttaaat ttttattctt tttcttattt aaacatattt ttcttaactt     5880

ttgtgggtac atagtgtgtg tatatattta tgccatatat ggcatatttt gatacaggca     5940

tatgaatagg tattaatcac atcagggcaa atgaaatatc catcaactcc agcatttatc     6000

atttgtatta caaaccgatt ctacactttt agttacttta aaatgtacaa gtaaattgct     6060

attgactata gggtcatttt catgggtata ataaaaatta tatacaagta taaataaaat     6120

cctgagtctt aaaattctga gtcctgctta aacattttaa aaattttgtt atgtattttt     6180

ctttgaacat gtctctctgc ctgcaaacat aacagaattt tagtattggt ttacatagag     6240

ttaactatac ccatatatta ctctaaaaat aaatgttaag tgcaagaaag ttatggactg     6300

tttttgtgtg agtgtgagtt tgtacctatt ttcaaaagaa aagagcaata ttggagcaaa     6360

acaaatattt taataaagta atgtactaga caactgaaaa cttc                      6404


<210>  2569
<211>  6550
<212>  DNA
<213>  homo sapiens

<400>  2569
aataaagaac gaggacactg cggggtgtgc ggcggcccaa gcggtttcaa acggcttaga       60

gcaggccgct tggttctgac ccagctgagg aaatactctt aattctaagg aaaacctgga      120

agcacaatgg gagatgacag tgagtggttg aaactgccag ttgatcagaa atgtgaacac      180

aagctgtgga aagcaaggtt aagtgggtat gaagaggccc tgaagatctt ccagaaaata      240

aaggatgaaa agagcccaga gtggtccaaa tttttaggat tgatcaaaaa atttgtcact      300

gattccaatg cagtggttca attgaaagga ttagaagctg cacttgttta tgttgaaaat      360

gcccatgtag caggaaaaac cacaggagaa gttgtgtcag gtgttgtaag taaggtgttc      420

aatcaaccta aagctaaagc caaggagctg ggcatagaga tctgtcttat gtacatagag      480

attgagaaag gagaggctgt tcaagaagag ctcctgaaag gcttggacaa taagaatccc      540

aagatcatag tggcctgtat agagacactg aggaaagcct taagtgaatt tggttccaaa      600

atcatcttgc ttaagccaat tatcaaagtg ttgccaaaac tctttgagtc tcgagagaag      660

gctgttcgag atgaagccaa actaattgct gtggagattt acagatggat tcgggatgct      720

ctgagacccc cattacaaaa tataaactct gttcagttga aagaactaga agaagaatgg      780

gtcaaactgc caacaagtgc tcctagacct actcgatttc ttcgttccca acaagaacta      840

gaagctaaat tggaacaaca acagtctgct ggtggagatg ctgaaggagg tggtgatgat      900

ggtgatgagg tgccacaaat agatgcttat gagcttttag aagctgtaga aatcctttcc      960

aaacttccca aagactttta tgacaaaatt gaggcaaaaa aatggcaaga gagaaaagag     1020

gccctggagt ctgtagaagt actaataaaa aaccccaaac tggaagctgg cgattatgca     1080

gatttagtaa aagcattaaa gaaggttgtt ggaaaggaca ccaatgtcat gttggtggct     1140

ttggcagcaa aatgtcttac tggcctggct gttgggctaa ggaagaaatt tggacaatat     1200

gcaggacatg ttgtgccaac catcttggag aaattcaaag agaagaaacc tcaagtggta     1260

caagccctgc aggaggcaat tgatgcaatc ttccttacta ccacactaca gaacatcagt     1320

gaggatgttt tagcagtaat ggataataaa aatccaacca tcaagcagca gacatctctt     1380

tttattgcaa gaagtttccg ccactgcact gcttctaccc tgccaaagag cttgctaaag     1440

cccttttgtg ctgcactact taagcacatc aatgattctg ctcctgaagt cagagatgcc     1500

gcatttgaag cattgggtac tgctttgaag gtggttggcg agaaagcagt aaacccattc     1560

ctagctgatg tggacaaact caagcttgat aagatcaaag aatgttcaga aaaggtagaa     1620

ctgatacatg gtaagaaagc tggactagct gctgataaga aggaattcaa acctctgcct     1680

ggaaggactg ctgcttcagg ggctgcagga gataaggaca caaaggacat ttctgcaccc     1740

aaaccaggac ctctaaaaaa ggcacctgct gctaaggctg gtgggccacc aaaaaagggg     1800

aaaccagctg caccaggagg cgcagggaat actggaacca agaacaagaa aggactggag     1860

actaaagaaa tagtggagcc tgagctctcg atagaagtat gtgaagaaaa agcttcagct     1920

gttcttcccc ctacctgtat acagcttctt gacagcagta actggaaaga aaggctggct     1980

tgtatggaag agttccagaa ggctgttgag ctaatggacc gaactgaaat gccatgccag     2040

gcattagtga ggatgctagc caagaaacct ggatggaaag aaactaattt tcaggtgatg     2100

caaatgaagc ttcatatagt tgctttgatt gcccagaagg gaaatttttc caaaacgtca     2160

gctcaggttg tattagatgg ccttgtggac aagattggag atgtgaaatg tgggaacaat     2220

gcaaaagaag ctatgacagc aatagccgaa gcctgtatgt taccatggac tgctgaacag     2280

gttgtgtcaa tggctttctc acaaaagaat cccaaaaatc agtcagaaac tctgaattgg     2340

ctatcaaatg ccataaaaga atttggtttt tctgggttga atgtcaaagc tttcattagc     2400

aatgtgaaga cagctcttgc tgcaacaaac ccagctgtga ggactgctgc cataaccctg     2460

cttggcgtga tgtatctgta tgttggtccc tctttgcgaa tgttctttga ggatgagaag     2520

cctgccctcc tatcccagat agatgcagaa tttgagaaga tgcagggaca aagtccacct     2580

gctccaacca gaggaatttc caagcatagc acaagtggta cagatgaagg agaagatgga     2640

gatgaaccag atgacgggag caatgatgtc gttgatcttt tgccgaggac ggagatcagt     2700

gataaaatca cttcagagtt ggtatctaag attggtgata agaattggaa gattaggaaa     2760

gaaggcctag atgaagtggc aggtattatt aatgacgcaa aatttatcca accgaatata     2820

ggtgaacttc caactgcctt gaagggtcga ctcaatgatt caaataaaat cttggtacag     2880

caaacgctga atatcctgca acaactggca gtagccatgg gcccaaatat taagcaacat     2940

gtaaaaaatt taggcatccc tatcatcaca gtccttggag acagcaagaa caatgttcga     3000

gctgctgccc tagcgactgt gaatgcttgg gcagaacaga ctggcatgaa ggaatggctg     3060

gaaggagaag atctttctga agagctcaaa aaggaaaatc ctttcttgag gcaagagctt     3120

ctgggctggc tggctgagaa actacctact cttcgttcca cccctacaga ccttatcctt     3180

tgtgttcctc atctctactc ctgcctagaa gatcgaaatg gagatgtgcg aaagaaggcc     3240

caagatgcct tgccattctt catgatgcat ttaggatatg aaaaaatggc caaggctact     3300

gggaaactaa agccaacttc taaagatcag gtattggcca tgctagagaa agccaaagtt     3360

aacatgccag ccaagcctgc tccacccact aaagcaactt ctaaaccaat gggagggtcc     3420

gctccagcca aattccagcc tgcatcagca cctgctgaag attgtatttc cagcagtaca     3480

gaacccaaac ctgatccaaa aaaggccaaa gctccaggat tatcctctaa agcaaagagt     3540

gcacaaggga agaagatgcc aagcaaaacc agcttaaagg aggatgaaga caaatccggg     3600

cctattttta ttgttgttcc aaatggaaaa gagcaaagga tgaaagatga aaaaggattg     3660

aaggtgctaa agtggaattt tactacccca cgggatgaat acattgagca actaaagact     3720

caaatgtcta gctgtgtggc taaatggtta caagatgaga tgtttcactc agactttcag     3780

catcataaca aagcccttgc tgttatggtt gatcacttgg agagtgaaaa agaaggagtt     3840

attggttgcc tggatcttat cttaaagtgg cttaccctga ggttttttga caccaataca     3900

agcgtcctga tgaaagcact agaatattta aaattgctct tcaccttgct aagtgaagaa     3960

gaatatcatc ttactgagaa tgaagcatct tccttcatcc cctatcttgt cgtcaaggtt     4020

ggagaaccaa aggatgtcat tcgtaaagat gttcgtgcca tcctgaaccg gatgtgcctt     4080

gtctacccag ctagcaagat gtttcccttt atcatggaag gaaccaaatc caaaaactct     4140

aagcagagag cagagtgcct ggaagagctg ggatgtctgg ttgagtccta tggcatgaat     4200

gtttgccaac caaccccagg aaaagcctta aaggaaatag ctgttcacat aggagaccgt     4260

gacaatgctg tacgcaatgc tgcactcaac accattgtaa cggtgtacaa tgtacatggg     4320

gatcaggtgt tcaaactgat tggaaatctt tctgaaaagg atatgagcat gctcgaggag     4380

aggattaagc ggtcagcaaa gagaccctct gctgcaccaa taaaacaggt ggaagagaaa     4440

cctcagcgtg cacagaacat aagctccaat gccaacatgt tacgcaaggg accagctgag     4500

gacatgtctt ccaaactcaa ccaagcccga agcatgagtg ggcatcctga ggcagcccag     4560

atggtccgcc gagaattcca gctggatcta gatgagattg agaatgacaa tggtacagtc     4620

cgatgtgaaa tgccagaact tgttcagcac aaactggatg acatttttga gccagtcctt     4680

attcctgaac ccaagatccg ggctgtttct ccacacttcg atgacatgca cagtaataca     4740

gcatccacaa tcaatttcat tatctcccaa gtagccagtg gtgacatcaa cacaagtatc     4800

caagctctga cacagctgtt tcagatagag agccttgccc gggaggcctc cactggagta     4860

ctaaaagacc taatgcatgg cctcatcacc ttaatgctgg attctcggat tgaagatctt     4920

gaggaaggac aacaggtcat ccgctctgtg aacctcttgg tggtgaaggt tctggagaag     4980

tcagaccaga ccaacatcct gagtgcccta cttgttttgc tccaagacag cctgctagca     5040

acagccagtt ctcccaaatt ctcagagctt gttatgaagt gtctctggag aatggttcga     5100

ctgttgcctg ataccatcaa tagcattaac ctagacagaa ttcttctgga tatccacatt     5160

ttcatgaagg tcttccccaa agagaaactg aagcaatgca aaagtgaatt tcccataagg     5220

accctaaaga ccctgctaca caccttatgc aaattaaaag ggcccaagat cctggaccac     5280

ctaacgatga tcgacaacaa aaacgagtct gagctggagg cccatctctg ccggatgatg     5340

aagcacagta tggaccagac tgggagcaag tctgataagg aaacagaaaa gggagcatct     5400

cgaatagatg aaaaatcatc aaaggccaaa gtgaatgatt tcttagctga gatttttaag     5460

aagattggct ctaaagaaaa cactaaagag ggactagcag agttatatga atataagaag     5520

aaatactcag atgctgacat tgaaccattt ctgaaaaatt cctcacagtt cttccagagc     5580

tatgtcgaaa gaggccttcg ggtgattgag atggagaggg agggcaaagg tcgtatttcc     5640

acttcaacag gcatctcccc tcagatggaa gtcacatgtg tgcccacgcc cacaagcaca     5700

gtgtcctcca taggtaacac aaatggggaa gaagtggggc catctgtcta cttggaaagg     5760

ctaaagatcc tccgacagcg atgtggtctg gacaacacaa agcaagatga ccgacctcct     5820

ttgacctctt tgctctccaa accagcagtt cctactgtcg cctcttccac agacatgctc     5880

cacagcaaac tctctcagct ccgggagtca cgggagcagc accagcattc agacctggat     5940

tctaaccaga ctcactcttc aggaactgtg acctcctcct cctccacagc taacatagac     6000

gacttgaaaa aaagactgga gagaataaag agcagtcgca aatgaagctg ccccactccc     6060

ccggcaccct gcagctttag tttactaaac tagaagtcct catagtttaa aatggcctca     6120

gcaggcctag tgtatacaaa ctggttgtat gtatcatgcc gtggagctag ggggaggagt     6180

cattgtggca caagtatttg tacatactct gcttctctct gtcagcgtcc tgctgctcta     6240

gaagactgtc cgtggatgag tttagtgtac agacttgtaa acagctgccc cctctctgct     6300

cagtctagtt cccagatcct tttcttttct ttttaattgc tcatttgtaa aattgtccta     6360

atctttccta gctttttaat agttaatatt agaaactctt taatagtttt cctttcagtt     6420

tgtgagctct tctctgtcgc cctgaagggt cactgtattc tgtatgaatg catggcatga     6480

tacaactaat ttaagagtct tttataaata aagtttgcat taactatacc tgacaaaaaa     6540

aaaaaaaaaa                                                            6550


<210>  2570
<211>  834
<212>  DNA
<213>  homo sapiens

<400>  2570
ggcggcgtgt ttgaaagcga ggccaaagtg ggtgggagcg cgtgctgttg ggagttgctt       60

ggaggttggc ggcgcggggc tgaaggctag caaaccgagc gatcatgtcg cacaaacaaa      120

tttactattc ggacaaatac gacgacgagg agtttgagta tcgacatgtc atgctgccca      180

aggacatagc caagctggtc cctaaaaccc atctgatgtc tgaatctgaa tggaggaatc      240

ttggcgttca gcagagtcag ggatgggtcc attatatgat ccatgaacca gaacctcaca      300

tcttgctgtt ccggcgccca ctacccaaga aaccaaagaa atgaagctgg caagctactt      360

ttcagcctca agctttacac agctgtcctt acttcctaac atctttctga taacattatt      420

atgttgcctt cttgtttctc actttgatat ttaaaagatg ttcaatacac tgtttgaatg      480

tgctggtaac tgctttgctt cttgagtaga gccaccacca ccatagccca gccagatgag      540

tgctctgtgg acccacagcc taagctgagt gtgaccccag aagccacgat gtgctctgta      600

tccagaacac acttggcaga tggaggaagc atctgagttt gagaccatgg ctgttacagg      660

gatcatgtaa acttgctgtt tttgtttttt cctgccgggt gttgtatgtg tggtgacttg      720

cggatttatg tttcagtgta ctggaaactt tccattttat tcaagaaatc tgttcatgtt      780

aaaagccttg attaaagagg aagtttttat aatctaaaaa aaaaaaaaaa aaaa            834


<210>  2571
<211>  637
<212>  DNA
<213>  homo sapiens

<400>  2571
actaaacttc cgggcgcgga ggtttgcgcg ccttggtgag ccgttggcgt ggtggtcccg       60

gagtgatcct ggcagccggt ggggaagaca aggagggttt gagcatggca gaaggaaaca      120

ccctgatatc agtggattat gaaatttttg ggaaggtgca aggggtgttt ttccgtaagc      180

atactcaggc tgagggtaaa aagctgggat tggtaggctg ggtccagaac actgaccggg      240

gcacagtgca aggacaattg caaggtccca tctccaaggt gcgtcatatg caggaatggc      300

ttgaaacaag aggaagtcct aaatcacaca tcgacaaagc aaacttcaac aatgaaaaag      360

tcatcttgaa gttggattac tcagacttcc aaattgtaaa ataatggcct gaatttaagt      420

tttctaagat aaactcagtg gtttggtttt tattattaat agagatagaa ctattgtgtg      480

ttaatattag cattagtcaa taagttattt taatgtcaga tttttgaatg ttattatata      540

ttacctgtat gatggaagga ttaccactgt acacaaatct aatcaataaa aacgttagaa      600

ccttctgctt agagtacttt taaaaaaaaa aaaaaaa                               637


<210>  2572
<211>  5836
<212>  DNA
<213>  homo sapiens

<400>  2572
gctttgccca gtagttggaa agtgaactcg actcgtgatg gttctcctgt cactttggtt       60

gatagcagcc gctctggtag aggttaggac ttcagctgat ggacaagctg gtaatgaaga      120

aatggtgcaa atagatttac caataaagag atatagagag tatgagctgg tgactccagt      180

cagcacaaat ctagaaggac gctatctctc ccatactctt tctgcgagtc acaaaaagag      240

gtcagcgagg gacgtgtctt ccaaccctga gcagttgttc tttaacatca cggcatttgg      300

aaaagatttt catctgcgac taaagcccaa cactcaacta gtagctcctg gggctgttgt      360

ggagtggcat gagacatctc tggtgcctgg gaatataacc gatcccatta acaaccatca      420

accaggaagt gctacgtata gaatccggag aacagagcct ttgcagacta actgtgctta      480

tgttggtgac atcgtggaca ttccaggaac ctctgttgcc atcagcaact gtgatggtct      540

ggctggaatg ataaaaagtg ataatgaaga gtatttcatt gaacccttgg aaagaggtaa      600

acagatggag gaagaaaaag gaaggattca tgttgtctac aagagatcag ctgtagaaca      660

ggctcccata gacatgtcca aagacttcca ctacagagag tcggacctgg aaggccttga      720

tgatctaggt actgtttatg gcaacatcca ccagcagctg aatgaaacaa tgagacgccg      780

cagacacgcg ggagaaaacg attacaatat cgaggtactg ctgggagtgg atgactctgt      840

ggtccgtttc catggcaaag agcacgtcca aaactacctc ctgaccctaa tgaacattgt      900

gaatgaaatt taccatgatg agtccctcgg agtgcatata aatgtggtcc tggtgcgcat      960

gataatgctg ggatatgcaa agtccatcag cctcatagaa aggggaaacc catccagaag     1020

cttggagaat gtgtgtcgct gggcgtccca acagcaaaga tctgatctca accactctga     1080

acaccatgac catgcaattt ttttaaccag gcaagacttt ggacctgctg gaatgcaagg     1140

atatgctcca gtcaccggca tgtgtcatcc agtgagaagt tgtaccctga atcatgagga     1200

tggtttttca tctgcttttg tagtagccca tgaaacgggc catgtgttgg gaatggagca     1260

tgatggacaa ggcaacaggt gtggtgatga gactgctatg ggaagtgtca tggctccctt     1320

ggtacaagca gcattccatc gttaccactg gtcccgatgc agtggtcaag aactgaaaag     1380

atatatccat tcctatgact gtctccttga tgaccctttt gatcatgatt ggcctaaact     1440

cccagaactt cctggaatca attattctat ggatgagcaa tgtcgttttg attttggtgt     1500

tggctataaa atgtgcaccg cgttccgaac ctttgaccca tgtaaacagc tgtggtgtag     1560

ccatcctgat aatccctact tttgtaagac taaaaaggga cctccacttg atgggactga     1620

atgtgctgct ggaaaatggt gctataaggg tcattgcatg tggaagaatg ctaatcagca     1680

aaaacaagat ggcaattggg ggtcatggac taaatttggc tcctgttctc ggacatgtgg     1740

aactggtgtt cgtttcagaa cacgccagtg caataatccc atgcccatca atggtggtca     1800

ggattgtcct ggtgttaatt ttgagtacca gctttgtaac acagaagaat gccaaaaaca     1860

ctttgaggac ttcagagcac agcagtgtca gcagcgaaac tcccactttg aataccagaa     1920

taccaaacac cactggttgc catatgaaca tcctgacccc aagaaaagat gccaccttta     1980

ctgtcagtcc aaggagactg gagatgttgc ttacatgaaa caactggtgc atgatggaac     2040

gcactgttct tacaaagatc catatagcat atgtgtgcga ggagagtgtg tgaaagtggg     2100

ctgtgataaa gaaattggtt ctaataaggt tgaggataag tgtggtgtct gtggaggaga     2160

taattcccac tgccgaaccg tgaaggggac atttaccaga actcccagga agcttgggta     2220

ccttaagatg tttgatatac cccctggggc tagacatgtg ttaatccaag aagacgaggc     2280

ttctcctcat attcttgcta ttaagaacca ggctacaggc cattatattt taaatggcaa     2340

aggggaggaa gccaagtcgc ggaccttcat agatcttggt gtggagtggg attataacat     2400

tgaagatgac attgaaagtc ttcacaccga tggaccttta catgatcctg ttattgtttt     2460

gattatacct caagaaaatg atacccgctc tagcctgaca tataagtaca tcatccatga     2520

agactctgta cctacaatca acagcaacaa tgtcatccag gaagaattag atacttttga     2580

gtgggctttg aagagctggt ctcagtgttc caaaccctgt ggtggaggtt tccagtacac     2640

taaatatgga tgccgtagga aaagtgataa taaaatggtc catcgcagct tctgtgaggc     2700

caacaaaaag ccgaaaccta ttagacgaat gtgcaatatt caagagtgta cacatccact     2760

ctgggtagca gaagaatggg aacactgcac caaaacctgt ggaagttctg gctatcagct     2820

tcgcactgta cgctgccttc agccactcct tgatggcacc aaccgctctg tgcacagcaa     2880

atactgcatg ggtgaccgtc ccgagagccg ccggccctgt aacagagtgc cctgccctgc     2940

acagtggaaa acaggaccct ggagtgagtg ttcagtgacc tgcggtgaag gaacggaggt     3000

gaggcaggtc ctctgcaggg ctggggacca ctgtgatggt gaaaagcctg agtcggtcag     3060

agcctgtcaa ctgcctcctt gtaatgatga accatgtttg ggagacaagt ccatattctg     3120

tcaaatggaa gtgttggcac gatactgctc cataccaggt tataacaagt tatgttgtga     3180

gtcctgcagc aagcgcagta gcaccctgcc accaccatac cttctagaag ctgctgaaac     3240

tcatgatgat gtcatctcta accctagtga cctccctaga tctctagtga tgcctacatc     3300

tttggttcct tatcattcag agacccctgc aaagaagatg tctttgagta gcatctcttc     3360

agtgggaggt ccaaatgcat atgctgcttt caggccaaac agtaaacctg atggtgctaa     3420

tttacgccag aggagtgctc agcaagcagg aagtaagact gtgagactgg tcaccgtacc     3480

atcctcccca cccaccaaga gggtccacct cagttcagct tcacaaatgg ctgctgcttc     3540

cttctttgca gccagtgatt caataggtgc ttcttctcag gcaagaacct caaagaaaga     3600

tggaaagatc attgacaaca gacgtccgac aagatcatcc accttagaaa gatgagaaag     3660

tgaaccaaaa aggctagaaa ccagaggaaa acctggacaa cctctctctt cccatggtgc     3720

atatgcttgt ttaaagtgga aatctctata gatcgtcagc tcattttatc tgtaattgga     3780

agaacagaaa gtgctggctc actttctagt tgctttcatc ctccttttgt tctgcattga     3840

ctcatttacc agaattcatt ggaagaaatc accaaagatt attacaaaag aaaaatatgt     3900

tgctaagatt gtgttggtcg ctctctgaag cagaaaaggg actggaacca attgtgcata     3960

tcagctgact ttttgtttgt tttagaaaag ttacagtaaa aattaaaaag agataccaat     4020

ggtttacact ttaacaagaa attttggata tggaacaaag aattcttaga cttgtattcc     4080

tatttatcta tattagaaat attgtatgag caaatttgca gctgttgtgt aaatactgta     4140

tattgcaaaa atcagtatta ttttaagaga tgtgttctca aatgattgtt tactatatta     4200

catttctgga tgttctaggt gcctgtcgtt gagtattgcc ttgtttgaca ttctataggt     4260

taattttcaa agcagagtat tacaaaagag aagttagaat tacagctact gacaatataa     4320

agggttttgt tgaatcaaca atgtgatacg taaattatag aaaaagaaaa gaaacacaaa     4380

agctatagat atacagatat cagcttacct attgccttct atacttataa tttaaaggat     4440

tggtgtctta gtacacttgt ggtcacaggg atcaacgaat agtaaataat gaactcgtgc     4500

aagacaaaac tgaaaccctc tttccaggac ctcagtaggc accgttgagg tgtcctttgt     4560

ttttgtgtgt gtgtgttctt ttttaatttt cgcattgttg acagatacaa acagttatac     4620

tcaatgtact gtaataatcg caaaggaaaa agttttggga taacttattt gtatgttggt     4680

agctgagaaa aatatcatca gtctagaatt gatatttgag tatagtagag ctttggggct     4740

ttgaaggcag gttcaagaaa gcatatgtcg atggttgaga tatttatttt ccatatggtt     4800

catgttcaaa tgttcacaac cacaatgcat ctgactgcaa taatgtgcta ataatttatg     4860

tcagtagtca ccttgctcac agcaaagcca gaaatgctct ctccagggag tagatgtaaa     4920

gtacttgtac atagaattca gaactgaaga tatttattaa aagttgattt tttttcttga     4980

tagtattttt atgtactaaa tatttacact aatatcaatt acatattttg gtaaactaga     5040

gagacataat tagagatgca tgctttgttc tgtgcataga gacctttaag caaactacta     5100

cagccaactc aaaagctaaa actgaacaaa tttgatgtta tgcaaacatc ttgcattttt     5160

agtagttgat attaagttga tgacttgttt cccttcaagg aaacattaaa ttgtatggac     5220

tcagctagct gttcaatgaa attgtgaatt agaaacattt ttaaaagttt ttgaaagaga     5280

taagtgcatc atgaattaca tgtacatgag aggagatagt gatatcagca taatgatttt     5340

gaggtcagta cctgagctgt ctaaaaatat attatacaaa ctaaaatgta gatgaattaa     5400

cctctcaaag cacagaatgt gcaagaactt ttgcatttta atcgttgtaa actaacagct     5460

taaactattg actctatacc tctaaagaat tgctgctact ttgtgcaaga actttgaagg     5520

tcaaattagg caaattccag atagtaaaac aatccctaag ccttaagtct tttttttttc     5580

ctaaaaattc ccatagaata aaattctctc tagtttactt gtgtgtgcat acatctcatc     5640

cacaggggaa gataaagatg gtcacacaaa cagtttccat aaagatgtac atattcatta     5700

tacttctgac ctttgggctt tcttttctac taagctaaaa attccttttt atcaaagtgt     5760

acactactga tgctgtttgt tgtactgaga gcacgtacca ataaaaatgt taacaaaata     5820

taaaaaaaaa aaaaaa                                                     5836


<210>  2573
<211>  1954
<212>  DNA
<213>  homo sapiens

<400>  2573
actggacaaa agcgtggtct ctggcgcggg gatctcagag tttcccgggc actcaccgtg       60

tgtagttggc atctccgcgc gtccggacac ccgatcccag catccctgcc tgcaggactg      120

ttcgtgttca gctcgcgtcc tgcagctgtc cgaggtgctc cagttggagg ctgaggttcc      180

cgggctctgt agctgagtgg gcggcggcac cggcggagat gcctgggaag aaggcgcgca      240

agaacgctca accgagcccc gcgcgggctc cagcagagct ggaagtcgag tgtgctactc      300

aactcaggag atttggagac aaactgaact tccggcagaa acttctgaat ctgatatcca      360

aactcttctg ctcaggaacc tgactgcatc aaaaacttgc atgaggggac tccttcaaaa      420

gagttttctc aggaggtgca cgtttcatca atttgaagaa agactgcatt gtaattgaga      480

ggaatgtgaa ggtgcattca tgggtgccct tggaaacgga agatggaata catcaaagtg      540

aatttctgtt caagttttcc cagattatca ttctttggga tgagagaaca ttataaaacc      600

actttgttta ttttaaagca agaatggaag acccttgaaa ataaagaagt aattattgac      660

acatttcttt tttacttaga gaatcgttct agtgtttttg ccgaagatta ccgctggcct      720

actgtgaagg gagatgacct gtgattagac tgggcggctg gggagaaaca gttcagtgca      780

ttgttgttgt tgctgttttt ggtgttttgc ttttcagtgc caactcagca cattgtatat      840

gattcggttt atacatatta ccttgttata atgaaaaaac tcattctgag aacactgaaa      900

tgttatactc agtgttgatt tcttcggtca ctacacaacg taaaatcatt tgtttctttt      960

gactcaaatt gtattgcttc tgttcagatg atctttcatt caatgtgttc ctgttgggcg     1020

ttactagaaa ctatggaaaa ctggaaaata actttgaaaa aattggataa agtataggag     1080

ggttacttgg ggccagtaaa tcagtagact gaacattcaa tataataaaa gaacatgggg     1140

attttgtata accagggata ataaaaagaa aaaagaagtt aatttttaat tgatgttttt     1200

gaaacttagt agaacaaata ttcagaagta acttgataag atatgaatgt ttctaaagaa     1260

gtttctaaag gttcggaaaa tgctccttgt cacattagtg tgcatcctac aaaaagtgat     1320

ctcttaatgt aaattaagaa tattttcata attggaatat acttttctta aaaaaaagga     1380

acagttagtt ctcatctaga atgaaagttc catatatgca ttggtgaata tatatgtata     1440

cacatactta catacttata tgggtatctg tatagataat ttgtattaga gtattatata     1500

gcttcttagt agggtctcaa gtaagtttca ttttttttat ctgggctata tacagtcctc     1560

aaataaataa tgtcttgatt ttatttcagc aggaataatt ttatttattt tgcctattta     1620

taattaaagt atttttcttt agtttgaaaa tgtgtattaa agttacattt ttgagttaca     1680

agagtcttat aactacttga atttttagtt aaaatgtctt aatgtaggtt gtagtcactt     1740

tagatggaaa attacctcac atctgttttc ttcagtatta cttaagattg tttatttagt     1800

ggtagagagt tttttttttc agcctagagg cagctatttt accatctggt atttatggtc     1860

taatttgtat ttaaacatat gcacacatat aaaagttgat actgtggcag taaactatta     1920

aaagttttca ctgttcaaaa aaaaaaaaaa aaaa                                 1954


<210>  2574
<211>  1954
<212>  DNA
<213>  homo sapiens

<400>  2574
actggacaaa agcgtggtct ctggcgcggg gatctcagag tttcccgggc actcaccgtg       60

tgtagttggc atctccgcgc gtccggacac ccgatcccag catccctgcc tgcaggactg      120

ttcgtgttca gctcgcgtcc tgcagctgtc cgaggtgctc cagttggagg ctgaggttcc      180

cgggctctgt agctgagtgg gcggcggcac cggcggagat gcctgggaag aaggcgcgca      240

agaacgctca accgagcccc gcgcgggctc cagcagagct ggaagtcgag tgtgctactc      300

aactcaggag atttggagac aaactgaact tccggcagaa acttctgaat ctgatatcca      360

aactcttctg ctcaggaacc tgactgcatc aaaaacttgc atgaggggac tccttcaaaa      420

gagttttctc aggaggtgca cgtttcatca atttgaagaa agactgcatt gtaattgaga      480

ggaatgtgaa ggtgcattca tgggtgccct tggaaacgga agatggaata catcaaagtg      540

aatttctgtt caagttttcc cagattatca ttctttggga tgagagaaca ttataaaacc      600

actttgttta ttttaaagca agaatggaag acccttgaaa ataaagaagt aattattgac      660

acatttcttt tttacttaga gaatcgttct agtgtttttg ccgaagatta ccgctggcct      720

actgtgaagg gagatgacct gtgattagac tgggcggctg gggagaaaca gttcagtgca      780

ttgttgttgt tgctgttttt ggtgttttgc ttttcagtgc caactcagca cattgtatat      840

gattcggttt atacatatta ccttgttata atgaaaaaac tcattctgag aacactgaaa      900

tgttatactc agtgttgatt tcttcggtca ctacacaacg taaaatcatt tgtttctttt      960

gactcaaatt gtattgcttc tgttcagatg atctttcatt caatgtgttc ctgttgggcg     1020

ttactagaaa ctatggaaaa ctggaaaata actttgaaaa aattggataa agtataggag     1080

ggttacttgg ggccagtaaa tcagtagact gaacattcaa tataataaaa gaacatgggg     1140

attttgtata accagggata ataaaaagaa aaaagaagtt aatttttaat tgatgttttt     1200

gaaacttagt agaacaaata ttcagaagta acttgataag atatgaatgt ttctaaagaa     1260

gtttctaaag gttcggaaaa tgctccttgt cacattagtg tgcatcctac aaaaagtgat     1320

ctcttaatgt aaattaagaa tattttcata attggaatat acttttctta aaaaaaagga     1380

acagttagtt ctcatctaga atgaaagttc catatatgca ttggtgaata tatatgtata     1440

cacatactta catacttata tgggtatctg tatagataat ttgtattaga gtattatata     1500

gcttcttagt agggtctcaa gtaagtttca ttttttttat ctgggctata tacagtcctc     1560

aaataaataa tgtcttgatt ttatttcagc aggaataatt ttatttattt tgcctattta     1620

taattaaagt atttttcttt agtttgaaaa tgtgtattaa agttacattt ttgagttaca     1680

agagtcttat aactacttga atttttagtt aaaatgtctt aatgtaggtt gtagtcactt     1740

tagatggaaa attacctcac atctgttttc ttcagtatta cttaagattg tttatttagt     1800

ggtagagagt tttttttttc agcctagagg cagctatttt accatctggt atttatggtc     1860

taatttgtat ttaaacatat gcacacatat aaaagttgat actgtggcag taaactatta     1920

aaagttttca ctgttcaaaa aaaaaaaaaa aaaa                                 1954


<210>  2575
<211>  4019
<212>  DNA
<213>  homo sapiens

<400>  2575
agtggcgtcc gttgtaagtg ctatgacaac agggcgaaga tggctcagag ttaggctgga       60

gaggggaggt gtcccttccg ctgcggccgt cgggtttctg ctacatccca ttcaccgcct      120

cctccatcct ttcctcctcg gtgtgagcag caggacttgc atttgttctc gcctgcctag      180

tgtcttccaa gggatagatg ccgtttcctc tgctggtctc tgggggtgac ggggggcgca      240

ggggagcttc ttgggggaat cactccaact ctgtggagct ggtggtgctg cctggtgggg      300

ctctctcttt gcccgggacg tggaacaact ttcagctgga ggacgagagg gaatagtgaa      360

gctaaaggtt gcttttctct gcaccgtccg ttcttgctcc ctctgctcca tcactgggac      420

cttgtcaggc gttcataaag caaaatttgc cgaacgaggg ttcgcagaaa ggtggggcag      480

agctcatctg acgtggcatc agtgtgaaag aaaatgtctt tatttaaagc ccgtgattgg      540

tggtctacta ttctgggaga taaagaagaa tttgatcaag gctgtttgtg tctggctaat      600

gttgacaata gtggaaatgg acaagataaa ataattgtgg gtagctttat gggataccta      660

aggatcttta gcccccatcc tgcaaaaaca ggagatggag ctcaagccga agatttgctt      720

ctagaagtgg atctacgaga tccagtactt caagtggaag taggaaagtt tgtttcaggt      780

accgaaatgc tacatttggc tgtgttacat tctagaaaac tttgtgtcta ctctgtctca      840

ggaaccttgg gtaatgtgga acatgggaac caatgtcaga tgaaattgat gtatgaacat      900

aatcttcaga gaacagcctg caatatgacc tatggatcat ttggtggtgt aaaaggtcga      960

gatttaattt gcatccagtc tatggatggg atgctgatgg tatttgagca ggagagctat     1020

gcttttggaa gatttctccc tggctttctt ctgcctggtc ctcttgccta cagttcccgt     1080

acagattcct tccttactgt ctcttcctgc caacaagtgg aaagttataa gtaccaggta     1140

cttgcttttg caacagatgc agataaaagg caggagactg aacagcaaaa acttggttct     1200

ggaaaaagac tagttgtgga ttggactcta aatattggag agcaagccct tgacatatgt     1260

attgtctctt tcaatcagtc ggcatcctct gtttttgttc ttggtgagag aaactttttt     1320

tgccttaagg ataatggaca aattcgattc atgaagaagc ttgattggag cccaagttgt     1380

tttctgccat attgctcagt ttctgaagga acaataaata ctttgattgg aaatcataat     1440

aacatgctgc atatttatca agatgtgaca ctgaagtggg ccacccaact tccccacatt     1500

cctgtagcag taagagtggg ctgtttgcat gatttaaagg gagtgatagt cactctgagt     1560

gatgatggtc acttgcagtg ttcatacctg gggacagatc cttctctgtt ccaagctcca     1620

aacgttcaat ctcgagaact aaactatgat gaacttgatg tagaaatgaa agaacttcag     1680

aaaatcatca aagatgttaa caaatcacaa ggtgtttggc ccatgactga gagagaagat     1740

gacttgaacg tttctgtcgt ggtttctcct aactttgatt cagtttctca agcgaccgat     1800

gttgaggtgg gaactgacct tgtcccttct gtcacggtga aggtcacact gcagaacaga     1860

gtgatattgc aaaaagccaa attatcagtc tacgtgcaac caccattaga attgacttgt     1920

gatcagttca cctttgaatt tatgacacca gatttgacta gaacagtaag cttttctgtt     1980

tatctgaaaa gaagttatac accatcagaa ttggaaggaa atgctgttgt ttcttattcc     2040

agaccaacag atcgaaatcc tgatggcatt ccgcgagtta tccaatgtaa atttagactt     2100

cccctaaagt taatttgcct accaggtcag ccttcaaaaa ctgcaagcca caaaattact     2160

attgatacca acaaatctcc agtcagtctt cttagtctct tcccaggttt tgccagtcag     2220

tcagatgatg atcaggtgaa tgtaatgggt tttcacttct taggaggtgc tcgaattact     2280

gttcttgctt ccaaaacttc tcaacgatat cgcattcaga gtgaacaatt tgaagatctt     2340

tggctcataa ccaatgagct tattcttcgc cttcaagaat attttgaaaa acagggagtc     2400

aaagattttg catgttcttt ttcgggatct ataccccttc aagaatattt tgagttgatt     2460

gatcatcatt ttgagctacg gataaatggt gaaaaattag aagaactctt atctgagaga     2520

gctgtacaat ttcgggccat tcaacgccgg ctactagcaa gattcaaaga taaaactcct     2580

gcccctcttc aacacctgga caccttgtta gatggaacct acaagcaggt aattgctcta     2640

gcagatgcag tggaggaaaa ccaaggcaat ctgttccagt cattcaccag gctgaagagt     2700

gccacccatt tggtgattct gctgatcgcg ctgtggcaga agcttagtgc tgaccaggtt     2760

gctattctgg aagcggcatt tctgccgcta caagaagaca ctcaagaatt gggctgggaa     2820

gaaacggtgg atgccgccat ttcccacctg ttgaagactt gcctgtcgaa gagttctaag     2880

gagcaggctt tgaacctcaa cagccagctg aacataccca aagacacaag ccaactgaag     2940

aaacatatca ccttgctctg cgatagatta tccaaaggtg gccgtctctg cctaagtacc     3000

gatgcagcag ccccacagac catggtcatg ccaggtggtt gtactacaat cccagagtca     3060

gacctagaag aaagatcagt agaacaagac tctacagaac tgtttaccaa ccacagacat     3120

ctcactgcag agacacccag gcctgaagtt tcacccctcc aaggagtctc ggaataattc     3180

aagtagagtt gtttggttga gaggaacatc cccatctcaa ggccgaacct gtgtgaacct     3240

catgccaagc acagatatag ggctggcgca ggtgcttcct aaagctcacc ttcctggaga     3300

tgacatgcat agaaagaggg gttgggactt tttacttcac taggagaact tgtaacacca     3360

tggggaagtc agctgaaact tgtcttgttt tgccaggaaa ggaagtagtt gcctttggtc     3420

atccatctgc taatagtcac agaatacagt gaaatgacat agttttgggt tagattttat     3480

aatgcaaaga ttcagatcca aaataatttc ataccccatt ttttcacaga attcttatat     3540

agtaaatgta tcaagtttaa taaagcatct cattgtcaaa taatatcttg gattttattt     3600

ataattagag ggatttatga gtgattgctc tacattattt cttcaaagga aaggaaagga     3660

attgaagact ttgctactct ctggtaagac ttgaatgtga ttattttata aataaaagaa     3720

ccactatgaa actttcatgt gatttgttct attaagctaa acgtggaaga agggaagttt     3780

tctagtattg tatgaaaatg tttaaatatt ttcaaggaag ctagtacatt aacatcccct     3840

tttcattacc ccattgggtg gcacctttta aaaatccagg ttattaaagg attcacactt     3900

tattacagtt aaaatttaag gtttttatgt gtaagaagtg aaagaaactt tgctaatttc     3960

aagttcgaat tacagttgtg agattgattt atttaaataa aaatatgcct ttgccagtt      4019


<210>  2576
<211>  4772
<212>  DNA
<213>  homo sapiens

<400>  2576
cggcgtcgcc gcaagagcgc gagaggcgcg gcgggaggag ccggcggcgc gcgcctccct       60

gggcccggac tcggccgcct cccgccgcct cccgcgcggc catggactga gcgccgccgg      120

ccaggccgcg gggatggggc cgccgctccc gctgctgctg ctgctactgc tgctgctgcc      180

gccacgcgtc ctgcctgccg ccccttcgtc cgtcccccgc ggccggcagc tcccggggcg      240

tctgggctgc ctgctcgagg agggcctctg cggagcgtcc gaggcctgtg tgaacgatgg      300

agtgtttgga aggtgccaga aggttccggc aatggacttt taccgctacg aggtgtcgcc      360

cgtggccctg cagcgcctgc gcgtggcgtt gcagaagctt tccggcacag gtttcacgtg      420

gcaggatgac tatactcagt atgtgatgga ccaggaactt gcagacctcc cgaaaaccta      480

cctgaggcgt cctgaagcat ccagcccagc caggccctca aaacacagcg ttggcagcga      540

gaggaggtac agtcgggagg gcggtgctgc cctggccaac gccctccgac gccacctgcc      600

cttcctggag gccctgtccc aggccccagc ctcagacgtg ctcgccagga cccatacggc      660

gcaggacaga ccccccgctg agggtgatga ccgcttctcc gagagcatcc tgacctatgt      720

ggcccacacg tctgcgctga cctaccctcc cgggtcccgg acccagctcc gcgaggacct      780

cctgccgcgg accctcggcc agctccagcc agatgagctc agccctaagg tggacagtgg      840

tgtggacaga caccatctga tggcggccct cagtgcctat gctgcccaga ggcccccagc      900

tccccccggg gagggcagcc tggagccaca gtaccttctg cgtgcaccct caagaatgcc      960

caggcctttg ctggcaccag ccgcccccca gaagtggcct tcacctctgg gagattccga     1020

agacccctcc agcacaggcg atggagcacg gattcatacc ctcctgaagg acctgcagag     1080

gcagccggct gaggtgaggg gcctgagtgg cctggagctg gacggcatgg ctgagctgat     1140

ggctggcctg atgcaaggcg tggaccatgg agtagctcga ggcagccctg ggagagcggc     1200

cctgggagag tctggagaac aggcggatgg ccccaaggcc accctccgtg gagacagctt     1260

tccagatgac ggagtgcagg acgacgatga tagactttac caagaggtcc atcgtctgag     1320

tgccacactc gggggcctcc tgcaggacca cgggtctcga ctcttacctg gagccctccc     1380

ctttgcaagg cccctcgaca tggagaggaa gaagtccgag caccctgagt cttccctgtc     1440

ttcagaagag gagactgccg gagtggagaa cgtcaagagc cagacgtatt ccaaagatct     1500

gctggggcag cagccgcatt cggagcccgg ggccgctgcg tttggggagc tccaaaacca     1560

gatgcctggg ccctcgaagg aggagcagag ccttccagcg ggtgctcagg aggccctcag     1620

cgacggcctg caattggagg tccagccttc cgaggaagag gcgcggggct acatcgtgac     1680

agacagagag gttctcggac cagcagtgac cttcaaagtg agcgccaatg tccaaaacgt     1740

gaccactgag gatgtggaga aggccacagt tgacaacaaa gacaaactgg aggaaacctc     1800

tggactgaaa attcttcaaa ccggagtcgg gtcgaaaagc aaactcaagt tcctgcctcc     1860

tcaggcggag caagaagact ccaccaagtt catcgcgctc accctggtct ccctcgcctg     1920

catcctgggc gtcctcctgg cctctggcct catctactgc ctccgccata gctctcagca     1980

caggctgaag gagaagctct cgggactagg gggcgaccca ggtgcagatg ccactgccgc     2040

ctaccaggag ctgtgccgcc agcgtatggc cacgcggcca ccagaccgac ctgagggccc     2100

gcacacgtca cgcatcagca gcgtctcatc ccagttcagc gacgggccga tccccagccc     2160

ctccgcacgc agcagcgcct catcctggtc cgaggagcct gtgcagtcca acatggacat     2220

ctccaccggc cacatgatcc tgtcctacat ggaggaccac ctgaagaaca agaaccggct     2280

ggagaaggag tgggaagcgc tgtgcgccta ccaggcggag cccaacagct cgttcgtggc     2340

ccagagggag gagaacgtgc ccaagaaccg ctccctggcc gtgctgacct atgaccactc     2400

ccgggtcctg ctgaaggcgg agaacagcca cagccactca gactacatca acgctagccc     2460

catcatggat cacgacccga ggaaccccgc gtacatcgcc acccagggac cgctgcccgc     2520

caccgtggct gacttttggc agatggtgtg ggagagcggc tgcgtggtga tcgtcatgct     2580

gacacccctc gcggagaacg gcgtccggca gtgctaccac tactggccgg atgaaggctc     2640

caatctctac cacatctatg aggtgaacct ggtctccgag cacatctggt gtgaggactt     2700

cctggtgagg agcttctatc tgaagaacct gcagaccaac gagacgcgca ccgtgacgca     2760

gttccacttc ctgagttggt atgaccgagg agtcccttcc tcctcaaggt ccctcctgga     2820

cttccgcaga aaagtaaaca agtgctacag gggccgttct tgtccaataa ttgttcattg     2880

cagtgacggt gcaggccgga gcggcaccta cgtcctgatc gacatggttc tcaacaagat     2940

ggccaaaggt gctaaagaga ttgatatcgc agcgaccctg gagcacttga gggaccagag     3000

acccggcatg gtccagacga aggagcagtt tgagttcgcg ctgacagccg tggctgagga     3060

ggtgaacgcc atcctcaagg cccttcccca gtgagcggca gcctcagggg cctcagggga     3120

gcccccaccc cacggatgtt gtcaggaatc atgatctgac tttaattgtg tgtcttctat     3180

tataactgca tagtaatagg gcccttagct ctcccgtagt cagcgcagtt tagcagttaa     3240

aagtgtattt ttgtttaatc aaacaataat aaagagagat ttgtggaaaa atccagttac     3300

gggtggaggg gaatcggttc atcaattttc acttgcttaa aaaaaatact ttttcttaaa     3360

gcacccgttc accttcttgg ttgaagttgt gttaacaatg cagtagccag cacgttcgag     3420

gcggtttcca ggaagagtgt gcttgtcatc tgccactttc gggagggtgg atccactgtg     3480

caggagtggc cggggaagct ggcagcactc agtgaggccg cccggcacac aaggcacgtt     3540

tggcatttct ctttgagaga gtttatcatt gggagaagcc gcggggacag aactgaacgt     3600

cctgcagctt cggggcaagt gagacaatca cagctcctcg ctgcgtctcc atcaacactg     3660

cgccgggtac catggacggc cccgtcagcc acacctgtca gcccaagcag agtgattcag     3720

gggctccccg ggggcagaca cctgtgcacc ccatgagtag tgcccacttg aggctggcac     3780

tcccctgacc tcacctttgc aaagttacag atgcacccca acattgagat gtgtttttaa     3840

tgttaaaata ttgatttcta cgttatgaaa acagatgccc ccgtgaatgc ttacctgtga     3900

gataaccaca accaggaaga acaaatctgg gcattgagca agctatgagg gtccccggga     3960

gcacacgaac cctgccaggc ccccgctggc tcctccaggc acgtcccgga cctgtggggc     4020

cccagagagg ggacatttcc ctcctgggag agaaggagat cagggcaact cggagagggc     4080

tgcgagcatt tccctcccgg gagaggagat cagggcgacc tgcacgcact gcgtagagcc     4140

tggaagggaa gtgagaaacc agccgaccgg ccctgcccct cttcccggga tcacttaatg     4200

aaccacgtgt tttgacatca tgtaaaccta agcacgtaga gatgattcgg atttgacaaa     4260

ataacatttg agtatccgat tcgccatcac cccctacccc agaaatagga caattcactt     4320

cattgaccaa gatgatcaca tggaaggcgg cacagaggca gctgtgtggg ctgcagattt     4380

cctgtgtggg gttcagcgta gaaaacgcac ctccatcccg cccttcccac agcattcctc     4440

catcttagat agatggtact ctccaaaggc cctaccagag ggaacacggc ctactgagcg     4500

gacagaatga tgccaaaata ttgcttatgt ctctacatgg tattgtaatg aatatctgct     4560

ttaatatagc tatcatttct tttccaaaat tacttctctc tatctggaat ttaattaatc     4620

gaaatgaatt tatctgaata taggaagcat atgcctactt gtaatttcta actccttatg     4680

tttgaagaga aacctccggt gtgagatata caaatatatt taattgtgtc atattaaact     4740

tctgatttca cattcaaaaa aaaaaaaaaa aa                                   4772


<210>  2577
<211>  2620
<212>  DNA
<213>  homo sapiens

<400>  2577
agagcaggcg agtcgggcgg atcgggtggg tagagtggtg ccgtccggtt gtttggtggg       60

aggcacgtaa gaccgctctg ggcacggggg cgctcacctc actggctcgt tcggttctag      120

gagcagatcc ggggtagagg gaaaagagct ccgggccagg ggctgccgtc gccgccgtcg      180

gggagtcagc ccgccagccc gccagctcgt cagcccgcca gccagcgctt cgcgggccct      240

gtcggtcccg gtaagcgggc ctgcgcttac cggaaagagg agcgtaagat gaaagagtat      300

cagaccaaac attgtctggc ttgcactgta aaactagtta gctgaagacg acttctcagg      360

tttcttcagg atgcctgcag cacttgtgga gaatagccag gttatctgtg aagtgtgggc      420

cagtaatcta gaagaagaga tgaggaagat ccgagaaatc gtgctcagtt acagttatat      480

tgccatggac acagaatttc caggtgttgt ggtgcgacca attggtgaat ttcgtagttc      540

catagattac caatatcagc ttctgcggtg caatgttgac cttttaaaaa ttatccagct      600

gggccttaca ttcacaaatg agaagggaga gtatccttct ggaatcaata cttggcagtt      660

caatttcaaa tttaacctta cagaggacat gtactcccag gattccatag atctccttgc      720

taactcagga ctacagtttc agaagcatga agaggaaggg attgacacac tgcactttgc      780

agagctgctt atgacatcag gagtggttct ctgtgacaat gtcaaatggc tttcatttca      840

tagtggctat gattttggct atatggtaaa gttgcttaca gattctcgtt tgccagaaga      900

ggaacatgaa ttctttcata ttctgaacct tttcttccca tccatttatg atgtgaaata      960

cctgatgaag agctgcaaaa atcttaaggg aggtcttcag gaagttgctg atcagttgga     1020

tttgcagagg attggaaggc agcaccaggc aggctcagac tcactgctga caggaatggc     1080

tttctttagg atgaaagagt tgttttttga ggacagcatt gatgatgcca agtactgtgg     1140

gcggctctat ggcttaggca caggagtggc ccagaagcag aatgaggatg tggactctgc     1200

ccaggagaag atgagcatcc tggcgattat caacaacatg cagcagtgat ggcgccaggc     1260

tctgcagggt gggcctgatc ccagagtggt gcttactgtg ctgactgtgt acttatcttc     1320

cccaagagaa aatgcttctt ttgagcacac tgtacctacc atctgcattg agcagaaaga     1380

cttttgtttt actgaagaca aaagatgttt ttattttaga cccagaagag aggagtttgc     1440

tctgaatttg taaataagtc ttccccattc ctcatactcg agcctctcct ctctggttgc     1500

ctcctgccac cagcatccat ggctcatttg acaccttttt aaatatcagg acaagtctga     1560

aacaaagtag taaaatgtat ataactctta cctgttgtca ttctttttct tttaaatttg     1620

ttgctaatct ctgataatga agattcttac tctgattctc agctgagctg tgagggcttc     1680

cagggaaaat ggaacaaaat ggtgttctta ggtaatgggt tgtagatact gagtcttcct     1740

ttccttttct gacccttctc gaggacattt gctttcctca cacttttgta gtctctcttt     1800

acatattact atatggaaat gaattgctct gtgctgaaat ttgaagacca gataatgaaa     1860

ctgaaaagca aacaatttta ctgaatctgt ctacccttca ttcatgagaa ctccagaatg     1920

agtgttgacc actgaagcat cttttaagtc tgtgttccat tgtgccattc aggtttgctg     1980

tcacatatgc atcatctgaa atcatttgaa atttttgtac aataaaatat cctggatttg     2040

atcctgaagg aaactagtaa gatcagattt ttgggtcatg tctgttgtat tttcagtaat     2100

gtgatttcag atggtcatct ggattctccc acttctctac tccattattt ctctactttt     2160

ccttccagca aacctgaaac gtgagggaga tggattaatg tgagtaacag gaatgtgtct     2220

ttaaaaagct agagtggtta catttaatca ggcagtaaga taatttgggt tcttgagttg     2280

ttttggagta atatcccaca actggggtag gaagctcagg acttttttct ttaaagctag     2340

tcatttcaaa agcatattgt atttttttga atgactacag tatggacaat ttcaaaaacc     2400

aaaacccact ttggattggt ggaagtaaaa actggtaact cactcaagtg aatgaatggt     2460

cttgcatttt aaaagcttat gggaaactca atttgaaatg attagaaaat gtcaagtatt     2520

ataagctggt atttaagatg cttgtaaata ctatttatgt ttttaatttt gtaaaataaa     2580

gatttctttt taaccactgg caaaaaaaaa aaaaaaaaaa                           2620


<210>  2578
<211>  7498
<212>  DNA
<213>  homo sapiens

<400>  2578
agaggagccg ggacaccgag ggaagaggcc ggagggagat cgcggagggg agggggcggg       60

aggggggtgg ggtatcctga gtcgtccgtg gtccggagtc tggaaggccc tagagcggcg      120

ccagtcgacc cgcctcgcca caacttgccc agaccagaca cgtttcatcc tgcgccctgc      180

aagaaggagc cggcctgcct ctctccgctt tgctgctcct cggcctccgc gggcccggcc      240

cgcgtcagca gcgaccctgg ggtctgggtc ccctgtgtcg cccccgcccg cctgcagcgc      300

ccggcacccg cccaggagcg cgcagctggg gttctaggga cgtatacttg agcaagagag      360

accacagctc ttgttcccgc tgatcctgca gcccagtgga tggagtccag aatctacaga      420

cctgccagga aagaaaaaaa aattcctgat gtctggtcca agcaggaatt ccccggtgga      480

ttggggaatg tctggctttt cctcagctta ttgatctctg tggtaaccac tggaggcccc      540

cagaagaccc atagaaatga gaggcctgag gtctacaagt cgctgctaga aatattttag      600

cctctccaaa gcccagaatg cagccccgac ccaagtttgt aagggttctg ggtgcacgct      660

gaccctgcgc gggcagacgc gccctttgct ccaggtccgg acctgggcgc tgctatagca      720

acgtcctgga cgcccagacc ttaggccgcc gccgccgcgg aagcgaggaa cccggccttc      780

tcccgctcct gagggctgtg gcggcggcgg cccgggaggc ggcccaggct gggtaaagac      840

cgcccggctc ctcctatgca agctgaggca gcggattggt tttcaagcat gcccttccag      900

aagcatgtct actacccgct cgccagcggc ccagaggggc ccgacgtcgc tgtggccgcc      960

gccgccgcgg gtgcggcctc catggcctgt gcgcccccca gcgcggcttc ggggcccctg     1020

cccttcttcc agttcaggcc gcggctggag agtgtggact ggcggcggct gagcgccatc     1080

gacgtggaca aggtggcggg ggctgtggac gtgctgacgc tgcaggagaa catcatgaac     1140

atcaccttct gcaagctgga agacgagaag tgcccacact gccagtcggg ggtggacccg     1200

gtgctgctga agctcatccg tctggcgcag ttcaccatcg agtacttgct gcactcacaa     1260

gagttcctca cctcgcagct gcacaccctg gaggagcggc tgcgcctgag ccactgcgac     1320

ggcgagcaga gcaagaagct gctcaccaag caggcggggg agatcaagac gctcaaggaa     1380

gagtgcaaac gccggaagaa gatgatctcc acccagcagc tgatgatcga ggccaaagcc     1440

aactattacc agtgccattt ttgtgacaag gcctttatga accaagcttt tctacaaagt     1500

cacattcaac gccgccacac tgaagaaaat tctcattttg agtatcagaa aaatgcacag     1560

attgagaagc tccggagtga gatcgtcgta ttgaaggaag agctgcagct caccaggtct     1620

gagctagagg ctgcacacca tgccagtgca gtcagattct ccaaggaata tgaaatgcag     1680

aaaacaaaag aggaagactt tttgaagtta tttgacaggt ggaaagaaga agaaaaggag     1740

aaactagttg atgaaatgga aaaagtcaag gagatgttta tgaaggaatt taaagaatta     1800

acttcgaaga attcagcatt agaatatcaa ctgtcagaaa tccagaagtc caatatgcag     1860

atcaagtcca acataggcac attaaaagat gcacacgagt ttaaagaaga ccgttctcca     1920

tatccccagg atttccataa tgtcatgcag cttcttgata gtcaggaaag caaatggaca     1980

gctcgagttc aagctattca tcaagaacac aagaaagaga agggtcggct cctgtcacat     2040

atagagaaac ttcgaacctc aatgatagat gatctaaatg caagcaatgt tttctataag     2100

aaaaggatag aagagctagg gcagagactc caggagcaga atgagctgat tataactcag     2160

agacagcaga ttaaagactt tacctgtaat ccattaaaca gtatcagtga acccaaagga     2220

aatcctttag cctggcaggc ttttgaatct cagccagctg ctccagctgt gcctatgaat     2280

gccccagccc tgcacacttt ggaaactaaa tcaagtctgc caatggtgca tgaacaggca     2340

ttctcgtcgc acatactgga accaatagaa gaactttcag aggaagaaaa aggaagggaa     2400

aatgaacaga aattaaataa caacaaaatg catttaagga aagctttgaa gagtaactcc     2460

tccctcacta agggactaag aacaatggtg gagcagaact tgatggagaa actggaaacc     2520

ttggggatta atgcagatat acgtggcatt tcaagtgatc agttgcatag agtactaaaa     2580

agtgtggaat cagaaagaca taagcaagaa agagaaatac ctaactttca tcaaattcga     2640

gaattccttg aacatcaagt cagctgtaaa attgaggaga aagcactact ctcttcagat     2700

cagtgcagtg tttctcaaat ggataccctt tcaactggag aagtacccaa aatgatacaa     2760

cttccttcca aaaacagaca actgattaga caaaaagctg tttctactga taggacatct     2820

gttccaaaaa ttaagaaaaa tgtcatggaa gatccttttc ccagaaagtc ttcaactatt     2880

acgacccctc cttttagttc agaggaggag caggaggacg acgacctcat ccgggcatac     2940

gcatccccag gcccacttcc tgtgccgcca ccacaaaaca agggcagctt cgggaagaac     3000

acagtgaaaa gtgacgcgga cgggaccgag ggaagcgaaa tcgaggacac tgatgattct     3060

cccaagcccg caggagtcgc cgttaaaaca cctactgaaa aagttgaaaa gatgtttcca     3120

catcgcaaaa atgtgaacaa accagtcggt ggaactaatg tccctgagat gtttatcaaa     3180

aaagaagaat tacaagaact aaagtgtgcg gatgtggagg atgaagactg ggacatatca     3240

tccctagagg aagagatatc tttgggaaaa aaatctggga aagaacagaa ggaacctcca     3300

cctgcgaaaa atgaaccaca ttttgctcat gtgctaaatg cctggggcgc atttaatcct     3360

aaggggccaa agggagaagg acttcaagaa aatgaatcaa gcacattaaa aagcagctta     3420

gtaactgtga ctgattggag cgacacttca gatgtctaat tccacatgtc agaagattat     3480

tccagaagcc agcagtattt cagtatcaca gtgtttcagt aatttgcctc catgattcta     3540

gtgcttctgc cttaccgtgt ttcccacagc aacacagaga ctgattcaaa gaacaatggt     3600

ctctttaatg gcacccaata cagtattgaa aatcagatca tcaacagtat ttcgaagcat     3660

gtaaaggtgt ttaagacttc cgctgctgct taaaaataac atgtcattga agtcataaaa     3720

agttttttct tcagaaaggt actctagtgt taagtgtatt tttttcaact aattttttag     3780

tgaatttttt ttaaacttac agcatgtttt ggtttgaatt actaaaactt taaaaaatat     3840

ttttcttatg tatgctgtcg tatcgtaggc gtttatatta taaaattctg ttagtagtct     3900

taaaattgaa ttggtggaac cactaatcct taaaagttag tctggttatt tttcatatag     3960

aagtaagttt aatccgagtg tggtggtgtt cacctttaat cccagctact tgggaggctg     4020

aggtgggagg ataacttgag cacaggagtt caagaccagc gtgggcaata tagcaagact     4080

ccacccctcc acaccccaaa aaagtaagtt taggattaga atatagctag gtccaatgtt     4140

aaatacattt tcctggagta catttgtcac attcagcttt gagccactgt aagcatgtta     4200

ctattaaatg gttggttatt ttatatagca tattctttat cttggatatt ttatgaataa     4260

agtatagtta ttttaagtgc caattaattt atcagactaa atagaaaata tttgagccat     4320

tactgaattc acatatgtat gttttttttt actatttaaa atacccaaca tgtattatga     4380

aatacctcaa aagtaattta gttacattct taaacaatga cattgtcgaa agaaagttct     4440

tataagctgt tttttgcatt tttataactt ggttatacta tattctgttt ccaagtaacc     4500

ttttaactaa aagatttgtt gggttttaga tctcttttca tttgtcaacc ttttcagtaa     4560

agccctctgt tacatcactg tgactgtggc tgtgttatta gagatgaatt ctgagttaaa     4620

tttgtactta ttaggggtct tacagaggga gaatctggcc ttgattgcta tgccatatga     4680

cattctgtcc taatggttag aacaaatctt tatctgtttc cacccaccct gggatccttt     4740

ttacttgtag cccattcctg ccctctaaaa gaatccttcc aacttcctat aggggccatt     4800

tcatgcagat atactcactt tatatgtatg tttctaaaag ctttagtgaa ggctgaatcc     4860

aagtttcatg tagtaggaca gagaacagaa ggccgaatcc aagtttcatg tggtaggaca     4920

gagaacggca atctacaaaa ctacaccaag cctaagatgg cccatgtgcc actttgttca     4980

ttcatttatt tattcagcag atatttattg aaccacttgg tctggtttgg ttttgaacac     5040

gcactaattc atttaattac aacaactttg cgatgtagtt attgttataa tcctcatcct     5100

aaaggtgtga gaaacagagt tattaagtaa gttgccagaa gccatacaag tacaaagtgt     5160

caaggggaga ctttaagcca ggtctctatt ccatgttttg tgtctgccat gttttcattc     5220

ctgagcagaa gagcttgggg aaatgaactt ttgctaagta aacccagtat ttaaattaag     5280

tcactatatc tgtgtctttt aagagcccct cctttagctt acatggttag ttgtatcttt     5340

tttttttttt ttttttgaga cagagtctca ctatgttgcc caggcttgag cgcagtggca     5400

ccatctcggc tcactacaac ctccgcctcc cagattcaag cgattttcct gcctcagcct     5460

cccaagtagc tgggattaca ggtgcccacc accatgcctg gcttaatttt ttgtattttt     5520

agtagagatg aggtttcacc atgttggcca gactggtctc gaactcctga cctcaaatga     5580

tccgctgtct tgtcctccca aagtgctggg attataggcg tgagccatcg cgccctgctg     5640

catttcattt ttttgtataa aatttggttt gttcgttttt gaggggaacc attcctttat     5700

gttgcccctt actgatgccc aactaatgtg tttctggtta ctaacagacc ttcatccccc     5760

accctcccta aattcttcgg tgtaatctaa gcgttatctg caccacttct gaataataaa     5820

tgtgtttgaa atgcacacct acacaaccct gtcccacact ggcctgtagg acctaatcta     5880

ccttcatgtc tttcagttga tttgtatttc tgcaaaagat atttcaagga ttatcaaggt     5940

atggaatttt ttttattttt tatcttttaa caaacttgtt catttccttt tctttccatt     6000

gagcacctct gaacaatgtg attctttttt ttaagtcttt cacacttcag gaaaatacta     6060

cattcaccca cgttgtgatt catatcggac agtttcttac tcaaagataa cacaaatacc     6120

aattcttatt catactttga aactatattt taccctagac tgccttggtt caaaggccta     6180

gtttcgacat tactgtggca aattatttaa gctctctgtt ttcatttctt tttctgtaaa     6240

tgcaggatga aaacaatatg tatctcctag gatggctgtg aggagtgagt gagacaggac     6300

atgaaaggtg tgtatgaact gtgataactg ttgcccttgt gggcatgtta tatagggctg     6360

gctctaggaa gaagcctgtg tcttttttca gaaatccctg gagcaactta aatgtcttta     6420

gaaatgacaa gtctctcagt tatccagtta gccgtaaaca ggttctggaa gacacaccta     6480

gatagaactc ggcccgtcag ttctgagtga ggcacgtacc acttgggctt gggatgtcct     6540

taacccattt atgcctgagg ttgcaatttt ttgaattttt ccaatcacac cttggcgatg     6600

accttgagca gtaggatata aataactccc acatgcttag tgttccaata atggaacact     6660

aggcataaac aggttttaat tggctcctca gtcaaccatg accaatatct ctatctcagc     6720

ttctgctgat gccctagctc agggctctgc attccgtgcc agggacgcct cagcccctta     6780

acatggatgt gccacatgac aggcaataat atattggccc cattagccct tcctggagca     6840

gtcataatga attacagtca tgacaggcac atgtaagaaa ccaaaatttg ctaaatatgt     6900

acatgagtct tcatcacagc atcgtttatg aaaacaacta aatattcact aatggtgcca     6960

gtggaataaa tcagagaaca tcccctgcta cgtaactctc tgcatacatc aaagagaatg     7020

gtgtggcttt gctttttcaa caatctactg agtggccatg ggcatgtgga tatggccatg     7080

aatgagcaag atcctctctg atcctgtaga agttaagttc taccagataa cttgctgctt     7140

caacaaaaag atttaccttt ttaaataaat gttgtagaat acttaaaaaa aacaaactag     7200

aatttgcctg tgtgcagcca gtaacatgtc tatttaacct ggacaccttt tgaggaatat     7260

tctcagattg cccccatgct gtttataaga cattgttcct tatacacctg tttatgaatg     7320

aaaagaaaca taaggagtgg gtacaaagac ttctatctat gaatgattaa aaaggctaga     7380

gtacgaatac ttcttgaacc tttggtacta aatgcttttc atgttctata taaatgtaga     7440

aaacatttta caaatcctgt aaataaactg tttatttttt atagaaagcc aaaaaaaa       7498


<210>  2579
<211>  1131
<212>  DNA
<213>  homo sapiens

<400>  2579
tggagagagc ggctctcgtg gctggggagt tggatgcacc aaacctgtgt gcggctggag       60

agggaggctt ctgccagacc ctctcccggg cctgtcctgc cacccaggcc cctccccagt      120

ctcacactga gctccagatc agggaagggc cgaaaaggac gatcagggca gccgcagaag      180

gggcgccctg cgtgggacgg gtccgttgcg cgcctggtaa ccgaggggga agggaagggg      240

cctctggcgt gcggggcggt gtcgcgcagg tcccaccccg cctgcccgcg ccgcccattg      300

gtcccgagcg cgatgacttg gcgggcggag caggaaggaa accgctcccg agcacggcgg      360

cggcgtcgtc tcccggcagt gcagctgccg ctaccgccgc cctctgcccg ccggcccgtc      420

tgtctacccc cagcatgagc ggcctgcgcg tctacagcac gtcggtcacc ggctcccgcg      480

aaatcaagtc ccagcagagc gaggtgaccc gaatcctgga tgggaagcgc atccaatacc      540

agctagtgga catctcccag gacaacgccc tgagggatga gatgcgagcc ttggcaggca      600

accccaaggc caccccaccc cagattgtca acggggacca gtactgtggg gactatgagc      660

tcttcgtgga ggctgtggaa caaaacacgc tgcaggagtt cctgaagctg gcttgagtca      720

agcctgtcca gagttcccct gctggactcc atcaccacac tccccccagc cttcacctgg      780

ccatgaagga ccttttgacc aactccctgt cattcctaac ctaaccttag agtccctccc      840

ccaatgcagg ccacttctcc tccctcctct ctaaatgtag tcccctctcc tccatctaaa      900

ggcaacattc cttacccatt agtctcagaa attgtcttaa gcaacagccc caaatgctgg      960

ctgcccccag ccaagcattg gggccgccat cctgcctggc actggctgat gggcacctct     1020

gttggttcca tcagccagag ctctgccaaa ggccccgcag tccctctccc aggaggaccc     1080

tagaggcaat taaatgatgt cctgttccat tggcaaaaaa aaaaaaaaaa a              1131


<210>  2580
<211>  6832
<212>  DNA
<213>  homo sapiens

<400>  2580
gggcaagctg gaaaagcgtg tgggtgagac cctcgcacaa ccccttttca ttgtctgtgt       60

gtggcgcctg cgcagtaagg gatcgttgga actgggcagg aggggatagg gtccggctcc      120

tcgccctttc ccgaggcgcc tgcgcactag gcagtcggtc tttgccgtta ccgctatgtg      180

tggggcgtgt gtggaataac gttattgccc agcggagctg agggccccgg agctcgaccg      240

cagcggcagc gacgacaaca gcggcgacga cgacgacgac gaggtggggg gaggacggcg      300

tgcgagagac tcacgggacg cgacgcgccc cgcctccccc gtccggtccc tctctccacg      360

gtaaggggat gacgtagctt tgccaaagac ttagaagcta agcagaaaat gagcttaaca      420

tcctggtttt tggtgagcag tggaggcact cgccacaggc tgccacgaga aatgattttt      480

gttggaagag atgactgtga gctcatgttg cagtctcgta gtgtggataa gcaacacgct      540

gtcatcaact atgatgcgtc tacggatgag catttagtga aggatttggg cagcctcaat      600

gggacttttg tgaatgatgt aaggattccg gaacagactt atatcacctt gaaacttgaa      660

gataagctga gatttggata tgatacaaat cttttcactg tagtacaagg agaaatgagg      720

gtccctgaag aagctcttaa gcatgagaag tttaccattc agcttcagtt gtcccaaaaa      780

tcttcagaat cagaattatc caaatctgca agtgccaaaa gcatagattc aaaggtagca      840

gacgctgcta ctgaagtgca gcacaaaact actgaagcac tgaaatccga ggaaaaagcc      900

atggatattt ctgctatgcc ccgtggtact ccattatatg ggcagccgtc atggtggggg      960

gatgatgagg tggatgaaaa aagagctttc aagacaaatg gcaaacctga agaaaaaaac     1020

catgaagctg gaacatcagg gtgcggcata gatgccaagc aagttgagga acaatctgca     1080

gctgcaaatg aagaagtact ttttcctttc tgtagggaac caagttattt tgaaatccct     1140

acaaaagaat tccagcaacc atcacaaata acagaaagca ctattcatga aatcccaaca     1200

aaagacacgc caagttccca tataacaggt gcagggcatg cttcatttac cattgaattt     1260

gatgacagta ccccagggaa ggtaactatt agagaccatg tgacaaagtt tacttctgat     1320

cagcgccaca agtccaagaa gtcttctcct ggaactcaag acttgctggg gattcaaaca     1380

ggaatgatgg cacccgaaaa caaagttgct gactggctag cacaaaacaa ccctcctcaa     1440

atgctatggg aaagaacaga agaggattct aaaagcatta aaagtgatgt tccagtgtac     1500

ttgaaaaggt tgaaaggaaa taaacatgat gatggtacgc aaagtgattc agagaacgct     1560

ggggctcaca ggcgctgtag caaacgtgca actcttgagg aacacttaag acgccaccat     1620

tcagaacaca aaaagctaca gaaggtccag gctactgaaa agcatcaaga ccaagctgtt     1680

gtgtttggag tagatgacaa tcaggattat aataggcctg ttatcaacga aaaacataaa     1740

gatctaataa aagattgggc tctcagttct gctgcagcag taatggaaga aagaaaacca     1800

ctgactacat ctggatttca ccactcagag gaaggcacat cttcatctgg aagcaaacgt     1860

tgggtttcac agtgggctag tttggctgcc aatcatacaa ggcatgatca agaagaaagg     1920

ataatggaat tttctgcacc tcttccttta gagaatgaga cagagatcag tgagtctggc     1980

atgacagtga gaagtactgg ctctgcaact tccttggcta gccagggaga gagaaggaga     2040

cgaactcttc cccagcttcc aaatgaagaa aagtctcttg agagccacag agcaaaggtt     2100

gtaacacaga ggtcagagat aggagaaaaa caagacacag aacttcagga gaaagaaaca     2160

cctacacagg tataccagaa agataaacaa gatgctgaca gacccttgag taaaatgaac     2220

agggcagtaa atggagagac tctcaaaact ggtggagata ataaaaccct acttcactta     2280

ggcagctctg ctcctggaaa agagaaaagt gaaactgata aggaaacttc tttggtaaag     2340

caaacattag caaaacttca acaacaagaa caaagggagg aggctcagtg gacacctact     2400

aaattgtctt ccaaaaatgt ttcaggtcag acagataaat gtagggagga aacttttaaa     2460

caagaatcac aacctccaga aaaaaattca ggacattcta caagcaaagg agacagagtg     2520

gcacaaagtg agagcaagag aagaaaagct gaggaaattc tgaaaagtca gactccaaag     2580

ggaggagaca agaaggaatc ctccaagtca ttagtgcgac aagggagctt cactatagaa     2640

aaacccagcc caaacatacc catagaactt attccccata taaataaaca gacttcctct     2700

actccttctt ctttagcatt aacatctgca agtagaatac gagaaagaag tgagtctttg     2760

gatcctgatt ctagtatgga cacaaccctt attctaaaag acacagaagc agtaatggct     2820

tttctagaag ctaaactacg tgaagataat aaaactgatg aaggaccaga tactcccagt     2880

tataatagag acaattctat ttcaccagaa tctgatgtag atacagctag tacaatcagt     2940

ctggttactg gagaaactga aagaaagtca acccaaaagc gaaagagttt cactagcctc     3000

tataaagata ggtgttccac aggttctcct tccaaagatg ttacaaaatc atcatcttca     3060

ggtgctaggg aaaaaatgga aaagaaaaca aaaagtcgtt ccacagatgt gggttcaaga     3120

gcagatggtc gtaaatttgt tcagtccagt gggagaataa gacagccctc agtagactta     3180

acagatgatg accaaacctc tagtgtacct cattctgcca tctctgatat tatgtcatct     3240

gatcaagaaa cttactcttg taaacctcat ggacggactc cacttacctc agctgatgag     3300

catgtacatt ccaaactgga aggaagtaaa gtaacgaaat ctaagacttc tccggtggta     3360

tctggttcat ctagtaaatc aaccaccctt ccaaggccac gacctaccag gacttccctc     3420

ttgcgcagag cacgacttgg tgaagcttca gacagtgaac ttgctgatgc tgacaaagca     3480

tctgttgctt ctgaagtatc cacaacaagt tctacatcaa aacctcccac aggaaggcgt     3540

aacatctctc ggattgattt attggctcag cctcgtagaa cacgacttgg ctcactgtca     3600

gctcgtagtg actctgaagc aacaatttct agaagtagtg cctcttcgag gaccgcagaa     3660

gccatcatta gaagtggagc cagactagta ccatcagata aattttctcc tagaattaga     3720

gctaacagta tctctcgact ctcagactcc aaggtcaaaa gtatgacctc agctcatggc     3780

tctgcttcag ccctgaaaac cactcgcttg cagagcgctg gatcagcaat gcctactagt     3840

tcttcattca aacaccggat taaagagcag gaagactaca tccgagattg gactgctcat     3900

cgagaagaga tagccaggat cagccaagat cttgctctca ttgctcggga gatcaacgat     3960

gtagcaggag agatagattc agtgacttca tcaggcactg cccctagtac cacagtaagc     4020

actgctgcca ccacccctgg ctctgccata gacactagag aagaggtagg agatcttcat     4080

ggagaaatgc ataagttggt tgatcgtgtt tttgatgaaa gcctcaactt ccgaaagatt     4140

cctccattag ttcattccaa aacaccagaa ggaaacaacg gtcgatctgg tgatccaaga     4200

cctcaagcag cagagcctcc cgatcactta acaattacaa ggcggagaac ctggagcagg     4260

gatgaagtca tgggagataa tctgctgctg tcatccgtct ttcagttctc taagaagata     4320

agacaatcta tagataagac agctggaaag atcagaatat tatttaaaga caaagatcgg     4380

aattgggatg acatagaaag caaattaaga gccgaaagtg aagtccctat tgtgaaaacc     4440

tcaagcatgg agatttcttc tatcttacag gaactgaaaa gagtagaaaa gcagctgcaa     4500

gcaatcaatg ctatgattga tcctgatgga actttggagg ctctgaacaa catgggattt     4560

cccagtgcta tgttgccatc tccaccgaaa cagaagtcca gccctgtgaa taaccaccac     4620

agcccgggtc agacaccaac acttggccaa ccagaagcta gggctcttca tcctgctgct     4680

gtttcagccg cagctgaatt tgagaatgct gaatctgagg ctgatttcag tatacatttc     4740

aatagattca accccgatgg ggaagaggaa gatgttacag tacaagaatg actttctctt     4800

gattgttgaa aaatcattac ctgtggaatg gctaggaata ttggaagcag catagtgttg     4860

atgtacgcaa aacaagacag cttggtcagc tacaatcttg gaatccctgt cttcttaatt     4920

ttatttattt atttttgacg tataatgtag tatatcaatc ctttcaaact atttagataa     4980

ccacttgatg cacaaatagg aaaaagcaga ttgtggcagt gtcgcctttt gtggttttat     5040

gattttcaaa ttgaatttaa tgattacacc ctttcccttc atagatcttt tttctttttt     5100

ttaagccatg ctgtgaccta caagcaaact aaatagccaa catttctgaa cccctaagtc     5160

tcctgtgcca agctgctccc tgaaatggac ttcttcatct gtacagattt gttaaaccat     5220

tctatttgct tcttaataat aggatttata ttagtactca ttaccattgg acacaatgac     5280

ataagtactc tccacagtaa agcagacctt tcacaacagt cactctgtgt cctaaaattt     5340

tccaacatag atgtgattta tataactttg ttgatacgta aattgtcttg gggtttacgg     5400

aaattaacta ttatgtttgc actaagattt gctgggagtg gtaggtggac atatctatat     5460

atcaataagg actaaccgtc ttttttgtac ataggagatt gataatactg tatttgtttt     5520

aagcccacag tgttttactc cactttcaaa aagatcaatt tggcactttt tttcattttt     5580

tttaatggaa ataagatttg gtctctcatt ttaggttaaa tgataactag aaagattaaa     5640

ctagacagat agtttaggtg gagtatattt ttaaaactca gaacatgtat attggtcctg     5700

tgttaccaag tttatatgtg acagttgaaa aagaaattcc cttgaaatga tcatgaggtt     5760

aaaattttct tcattagggg acttggagaa ccagtagtcg taagattagt tgatagtttc     5820

actcccaagc aatgaattgc ttctgtgtgt ttccctgtag gactcaatag taaatgctgt     5880

ctgtcttaca catttataag gaccctgcaa gacgacgaca aaggcctttg gcctgtgcta     5940

ctaaacaaga agcctatgaa aaatttcttc tttaaacttg ttttttctct ttccagtaag     6000

ttcacatttg gataatttta aaaagaaaag taattacctt tgtgtttcca gaacactata     6060

attggggtgt atcttaattc agttaaatat tattagtaga cctggatttt cccccttgac     6120

cccatcagtc tataaaggtt aaactgcaac ttttatgaaa tggtctttaa tatttccaca     6180

ataatcctgt gctatatttg ttttaagaaa caaagtaact ctatacactt caagacttta     6240

caggattttt taaatcctgt attgttggat caattaataa agatgcaaaa aaactttata     6300

gagatgtaaa aacaaaacta taatggatct cctatttttc tttaaataca aaaaaaaaaa     6360

ggtaaatgaa ctattctcct tgtaaagcta aattccccat tctgtctaat aaaggaagac     6420

tgaaaaaagg ttttaaagaa cataaatgga aagatacaaa tgctttgaag gaataaacga     6480

aatgttaaaa cagggtcaat ccatttgaag aaaaagttgg acaaaataat cagcattgct     6540

ccctctttta tttaatattt gggtactgat tatatccaca tggaagtaga aggtaaggag     6600

tttaggaaaa tactagaatc tactctgctt acattcttgt ttaagtgttt acacagtttg     6660

gttcaattat aaacatttgg ccttttacta tgttattttt attttgtatg aatacattat     6720

cctccttatt tatttttgtt acatttatta cttatgttat tttgttatgc atttacaact     6780

ccatttttaa ataaagtgtt tctggaactt taaaaaaaaa aaaaaaaaaa aa             6832


<210>  2581
<211>  3058
<212>  DNA
<213>  homo sapiens

<400>  2581
gtagctgaga tgcagagagc catcctgccc agacctagac aactcggaag tgggtttttc       60

agcctcctgc accggtgtcg cgtctgagtg cgactgatga gccagggggc gtcggtggaa      120

gcttggggga gaggctagtg gtaacaggcc gagctggatg gatgggtatg gggagagggg      180

caggacgttc agccctggga ttctggccga ccctcgcctt ccttctctgc agcttccccg      240

cagccacctc cccgtgcaag atcctcaagt gcaactctga gttctggagc gccacgtcgg      300

gcagccacgc cccagcctca gacgacaccc ccgagttctg tgcagccttg cgcagctacg      360

ccctgtgcac gcggcggacg gcccgcacct gccggggtga cctggcctac cactcggccg      420

tccatggcat agaggacctc atgagccagc acaactgctc caaggatggc cccacctcgc      480

agccacgcct gcgcacgctc ccaccggccg gagacagcca ggagcgctcg gacagccccg      540

agatctgcca ttacgagaag agctttcaca agcactcggc cacccccaac tacacgcact      600

gtggcctctt cggggaccca cacctcagga ctttcaccga ccgcttccag acctgcaagg      660

tgcagggcgc ctggccgctc atcgacaata attacctgaa cgtgcaggtc accaacacgc      720

ctgtgctgcc cggctcagcg gccactgcca ccagcaagct caccatcatc ttcaagaact      780

tccaggagtg tgtggaccag aaggtgtacc aggctgagat ggacgagctc ccggccgcct      840

tcgtggatgg ctctaagaac ggtggggaca agcacggggc caacagcctg aagatcactg      900

agaaggtgtc aggccagcac gtggagatcc aggccaagta catcggcacc accatcgtgg      960

tgcgccaggt gggccgctac ctgacctttg ccgtccgcat gccagaggaa gtggtcaatg     1020

ctgtggagga ctgggacagc cagggtctct acctctgcct gcggggctgc cccctcaacc     1080

agcagatcga cttccaggcc ttccacacca atgctgaggg caccggtgcc cgcaggctgg     1140

cagccgccag ccctgcaccc acagcccccg agaccttccc atacgagaca gccgtggcca     1200

agtgcaagga gaagctgccg gtggaggacc tgtactacca ggcctgcgtc ttcgacctcc     1260

tcaccacggg cgacgtgaac ttcacactgg ccgcctacta cgcgttggag gatgtcaaga     1320

tgctccactc caacaaagac aaactgcacc tgtatgagag gactcgggac ctgccaggca     1380

gggcggctgc ggggctgccc ctggcccccc ggcccctcct gggcgccctc gtcccgctcc     1440

tggccctgct ccctgtgttc tgctagacgc gtagatgtgg agggaggcgc gggctccgtc     1500

ctctcggctt ccccatgtgt gggctgggac cgcccacggg gtgcagatct cctggcgtgt     1560

ccaccatggc cccgcagaac gccagggacc gcctgctgcc aagggctcag gcacggaccc     1620

ctccccttct agtgcacgtg acaaggttgt ggtgactggt gccatgatgt ttgacagtag     1680

agctgtgtga gagggagagc agctcccctc gccccgcccc tgcagtgtga atgtgtgaaa     1740

catcccctca ggctgaagcc ccccaccccc accagagaca cactgggaac cgtcagagtc     1800

agctccttcc ccctcgcaat gcactgaaag gcccggccga ctgctgctcg ccgatccgtg     1860

gggccccctg tgcccgccac acgcacgcac acactcttac acgagagcac actcgatccc     1920

cctaggccag cggggacacc ccagccacac agggaggcat ccttggggct tggccccagg     1980

cagggcaacc ccggggcgct gcttggcacc ttagcagact gctggaacct tttggccagt     2040

aggtcgtgcc cgcctggtgc cttctggcct gtggcctccc tgcccatgtt cacctggctg     2100

ctgtgggtac cagtgcaggt cccggttttc aggcacctgc tcagctgccc gtctctggcc     2160

tgggcccctg ccccttccac cctgtgctta gaaagtcgaa gtgcttggtt ctaaatgtct     2220

aaacagagaa gagatccttg acttctgttc ctctctctcc tgcagatgca agagctcctg     2280

ggcaggggtg cctgggcccc agggtgtggc aggagaccca gtggatgggg ccagctggcc     2340

tgccctgatc ctctgcttcc tcctcacaac cccaagagcc cccagcccgg tccatccacg     2400

tctggagtct ggggagagga gcagggtctt aggactctca gctctgagca tccctggcag     2460

ggtcttcaac ctctaatctc ttcccttaag ccctgtggcc acacagccag gagagacttg     2520

ccgctggctc ccgcctcatt tcagcccagg gtgctcatcc aggggcccag aacagtccca     2580

cctgtgctgc tgtgcccaca gcacaaagcc aggcttcact cccaaaagtg cagccaggcc     2640

ctggagggtg atcctgccag cagccctaca gctccacacc ctacccaccc atcggcagcc     2700

cctctgctgt tccccaggga cctctcatac actggccagg aggctgcaga acgtgtgtct     2760

ccccctccct ccaagaggtc ctgctccctc tgccagaacc gtgtgtgggc gggtgggagg     2820

gcgctcgggg cccggcccct ccctctccct gctggtttta gttggtccct atgttggaag     2880

taaaaagtga agcactttat tttggttgtg tttgctcacg ttctgcttgg aagtggggac     2940

ccctcactgc gtccacgtgt ctgcgacctg tgtggagtgt caccgcgtgt acatactgta     3000

aattatttat taatggctaa atgcaagtaa agtttggttt ttttgttatt ttctttta       3058


<210>  2582
<211>  3112
<212>  DNA
<213>  homo sapiens

<400>  2582
actcggtgtc accacaggag gagactcagg caggccgcgc tccagcctca ccaggctccc       60

cggctcgccg tggctctctg agcccccttt tcagggaccc cagtcgctgg aacatttgcc      120

cagactcgta ccaaactttt ccgccctggg ctcgggatcc tggactccgg ggcctccccg      180

tcctcccctt tcccgggttc cagctccggc ctctggacta ggaaccgaca gcccccctcc      240

ccgcgtccct ccctctctct ccagccgttt tggggagggg ctctccacgc tccggatagt      300

tcccgagggt catccgcgcc gcactcgcct ttccgtttcg ccttcacctg gatataattt      360

ccgagcgaag ctgcccccag gatgaccacg ctggccggcg ctgtgcccag gatgatgcgg      420

ccgggcccgg ggcagaacta cccgcgtagc gggttcccgc tggaagtgtc cactcccctc      480

ggccagggcc gcgtcaacca gctcggcggt gtttttatca acggcaggcc gctgcccaac      540

cacatccgcc acaagatcgt ggagatggcc caccacggca tccggccctg cgtcatctcg      600

cgccagctgc gcgtgtccca cggctgcgtc tccaagatcc tgtgcaggta ccaggagact      660

ggctccatac gtcctggtgc catcggcggc agcaagccca agcaggtgac aacgcctgac      720

gtggagaaga aaattgagga atacaaaaga gagaacccgg gcatgttcag ctgggaaatc      780

cgagacaaat tactcaagga cgcggtctgt gatcgaaaca ccgtgccgtc agtgagttcc      840

atcagccgca tcctgagaag taaattcggg aaaggtgaag aggaggaggc cgacttggag      900

aggaaggagg cagaggaaag cgagaagaag gccaaacaca gcatcgacgg catcctgagc      960

gagcgagcct cagcacccca atcagatgaa ggctctgata ttgactctga accagattta     1020

ccactaaaga ggaaacagcg cagaagccga accaccttca cagcagaaca gctggaggaa     1080

ctggagcgtg cttttgagag aactcattac cctgacattt atactaggga ggaactggcc     1140

cagagggcga agctcaccga ggcccgagta caggtctggt ttagcaaccg ccgtgcaaga     1200

tggaggaagc aagctggggc caatcaactg atggctttca accatctcat tcccgggggg     1260

ttccctccca ctgccatgcc gaccttgcca acgtaccagc tgtcggagac ctcttaccag     1320

cccacatcta ttccacaagc tgtgtcagat cccagcagca ccgttcacag acctcaaccg     1380

cttcctccaa gcactgtaca ccaaagcacg attccttcca acccagacag cagctctgcc     1440

tactgcctcc ccagcaccag gcatggattt tccagctata cagacagctt tgtgcctccg     1500

tcggggccct ccaaccccat gaaccccacc attggcaatg gcctctcacc tcaggtgcct     1560

ttcattatct caagccagat atcgcgtaag tgaactgtcc acttggagct aaaactggcc     1620

ctgtttctgg tcttcgcagc ctagatatga agaatctgct ctgaaaacaa aaaaaaatta     1680

cccttttgtt ggggggggtg gggcagtggt cccaatagga gacaaaggag agtgattgat     1740

tttcttcctc caatagttgg tttcaaatcc ttttgaacac gttcgacaaa agcagtggag     1800

aagaggaaga cctggagcaa taaaagacaa atgcaacatt ttaaggcaat ggtttcacat     1860

ggttacatat caaaacatcc caattcttta gtgctgatca tcgaggagct agaacattcc     1920

atttgcttgt gtgcgtgcgt gcgtgtgtgt gtgtgtgtgt gtattgagat ttacccagac     1980

tggtttgggc aagcagactg ttctaaaata taatagaata ccctaaagta taacatgtcg     2040

atgttcgatg ctgatacttc tacaacttta aaactgctca tttcatgaag caagaatgga     2100

ggaatccttg actcttacac actggaaatt gaaataaaga taaatgcaac catttttagg     2160

aagctagact agctgtaaag gacctcctaa ataaattatt tgttactgta tcctcatttg     2220

taatctagtt gtcaataaat ggcccggaca tgtcttgcta acaggatatg ggctaccagg     2280

aagaaggact tgtttccctt tcctgtgtgg ggagaggtgt gtgacgtttt tccagttcac     2340

atttatttgg tagcccacct gggttggagg aagggcacgg tggagagaaa gtgacatgca     2400

ttcacatatc tgcttatcag tgtgcaatac tgtgtacctc atggatgctt tggcaatgcc     2460

caaggcgata taagcaaaat cagaagtata tttttgcagg tgcttttatt ttcacagccc     2520

ataattcata gtgatagagt gcagtgatgt ttgccatttg ctggacaacc aacacccggg     2580

ttgctccttt gattagagac cagatcagat aattatgctt ttaaactgat tacgtttaca     2640

ttcttctctt ttctatgaaa ggcagggcaa gaacagaagt gttcacatgg ctctcatgta     2700

cttttaaatt atacaatgat atccaatatt aaaagattat aggaactgag gtttacatac     2760

gtttgtgtgg tgacatttta gaatgtcaat aaatttgctt tttgagatgt tgagaggaac     2820

aagaaggtgg aaggcagtgt tatttatttc tttctattct tggaaccacg aatgaggtag     2880

gcacaaatac attcctttta gagttaagaa ctatgacgta gcgagttagt gagactagac     2940

atagtaccga atttagttca tgcattggtc ttagagggtg atggaacaag agaagtacta     3000

tctttgtgtt gcagcctcaa ccaacaacaa tgtgttgtaa aaatgtcttt catgtaaaaa     3060

gtgcagtaaa tatttactat ttataatgaa taaacagtta tgaaaacttg aa             3112


<210>  2583
<211>  16064
<212>  DNA
<213>  homo sapiens

<400>  2583
ccgcgcgtcc ctgtgcgtcc ccgggtccct gcgggcgggc gggcgcggtc gccgccgagc       60

aacccggcct gcgcccggca cgactgtaga tgtcaggctt tgcccgggga gccgagcggc      120

agcggggctg tgagtttcaa attaaccttc cgctttgttg ctgtgtaatg tggatccccg      180

aaggcccccc gccccgcccg ccccccttcc ccgggcggtg cgcgctgcaa actgcgagtt      240

gggcttcatt tacataaagc gattccgggc gggcggcggc agaggaggag gcggcggcgg      300

cgggcaggcc ggggacccgg acgccagcgc cgcgccccgt gggtgaatcc ccgccgcgtc      360

ccggggacct ccctccgggg acgggccgac cgccagccct gccgccacca tgagctcccc      420

tcccctgtct ccgggccccc tgctcctgac cagagccacc tccgagtcct ggggccagcg      480

ggaggtgggg agcatgccgc ctggggtggg tgagctcggg gctcgggtgc cactggaatt      540

tcccgttgtt gcgcatggcg gcgcggcccc cggacctgca agtgccgcct ccctccggag      600

gtgcgcggag gcttggtgtg ccaggtccga gcctccgtac tgggtgcaat gaaagctcca      660

cgcaggcctt accatggaag gctgtgactc gcccgtcgtc tcggggaagg acaatgggtg      720

cggtatccct cagcaccagc aatggactga actcaacagc acccacctcc ctgacaaacc      780

cagtagcatg gagcagtcca caggcgagag ccacgggccc ttggacagcc tgagggcccc      840

cttcaatgag cgcctcgcgg agagcaccgc gtcggccggg cccccctccg agcccgccag      900

caaggaggtc acctgcaacg aatgttcggc ctcctttgcc agcctccaga cctacatgga      960

gcaccactgc cccagcgcgc gccccccgcc acccctgaga gaggagagcg ccagcgacac     1020

cggtgaggag ggggacgagg agagtgacgt ggagaacctg gccggggaga tcgtctacca     1080

gccggacggc tccgcgtaca ttgtggagag cctgagccag ctgacccagg gcgggggcgc     1140

ctgtgggagt ggcagtggca gtgggcctct cccctcgctt ttcctgaact ctctccctgg     1200

cgcggggggc aagcaagggg acccttcgtg tgctgcaccc gtgtacccgc agatcatcaa     1260

cactttccac atagcctcat ccttcgggaa atggtttgag ggcccagacc aggctttccc     1320

gaatacctca gccctggcgg ggctcagccc cgtcctgcac agcttccgcg tgtttgacgt     1380

gcgacacaaa agcaacaagg attacctgaa cagcgacggt tctgccaaaa gctcctgcgt     1440

atccaaagat gttcccaaca atgtggacct gtccaaattc gatggctttg tgctctatgg     1500

caagaggaag cccatcctga tgtgtttctt gtgcaaactc tcctttgggt acgtccgttc     1560

gtttgtgacc cacgcggtgc atgaccatcg aatgaccctg agcgaagacg agcggaaaat     1620

tcttagcaat aagaacatct ccgctatcat ccaagggatc ggcaaagaca aggaacccct     1680

tgtaagtttt ctggaaccaa aaaacaaaaa ctttcaacac cctttagttt ccacagctaa     1740

cctcataggc cccggacaca gtttttatgg taaatttagt ggcattcgaa tggaagggga     1800

ggaagctctc ccagcgggct ccgccgctgg ccccgagcag ccccaggctg gtctcttgac     1860

ccccagcacc ctgttgaacc ttggcgggct caccagctcg gtactgaaga cccccattac     1920

ctcagtcccc ctggggcctc tggcttccag tcctaccaaa tcctcagagg gcaaggactc     1980

tggggcggca gaaggagaga agcaggaagt gggcgacggg gattgcttct ctgagaaggt     2040

agagccagcc gaagaggagg cggaggagga agaggaggag gaagaggcgg aggaggagga     2100

ggaagaagag gaggaggaag aagaggagga ggaagacgag ggttgcaaag gactctttcc     2160

aagcgagttg gatgaggaac tggaggacag gccccatgag gagcctgggg ccgcagcagg     2220

tagtagcagc aaaaaggacc ttgctctctc aaaccaaagc atttctaact cccccttaat     2280

gcctaacgtg ctccagaccc tgtcgagggg cacagcttct actagttcta attctgcttc     2340

ttcctttgtt gtctttgatg gtgcgaacag gaggaatcgt ttaagcttta acagtgaggg     2400

cgtcagggcc aatgtggcag agggcggcag gaggctggac ttcgctgacg aaagtgccaa     2460

taaagacaat gccacagcac cagaaccaaa tgaaagcaca gagggtgacg atgggggctt     2520

cgttccccat caccagcacg ctggctccct ctgcgagctt ggggttgggg agtgcccctc     2580

ggggagtggc gtggagtgcc ccaaatgcga cacggtcctg ggctcctccc gctcgctggg     2640

cggccacatg accatgatgc attctcgtaa ctcgtgtaag acactcaagt gccccaagtg     2700

caactggcac tataagtacc agcagaccct ggaggcacac atgaaggaga agcacccgga     2760

gccggggggc tcctgtgtct actgcaaaag cgggcagccc cacccccggc tggcacgagg     2820

cgagagctac acgtgtggtt acaagccttt ccgctgcgag gtgtgtaact actccacaac     2880

taccaaaggc aacctcagta ttcatatgca gtctgacaag catctcaaca acatgcagaa     2940

cctgcagaat ggaggggggg agcaggtctt cagccacact gccggggcgg cggcggcggc     3000

ggtggctgcg gcggcggcgg cagccaatat cagtagctcc tgcggggccc cctcgccgac     3060

caaaccaaaa accaaaccca cctggcggtg cgaggtgtgt gattatgaga ccaacgtggc     3120

caggaacctc cgcattcaca tgaccagtga gaagcacatg cataacatga tgttactgca     3180

acagaacatg acccagatcc aacacaaccg ccacctgggc ctcggcagcc tgccctcacc     3240

cgccgaggcc gagctctacc aatactacct ggcccagaac atgaacctgc ccaacctgaa     3300

gatggacagt gctgcctcgg acgcccagtt catgatgagc ggattccagc tggatcccgc     3360

cgggcccatg gccgccatga cgcctgctct agtgggcggt gagatccccc tagacatgcg     3420

gctcgggggc gggcagctgg tgtcagagga gctgatgaac ctgggcgaga gcttcatcca     3480

gaccaacgac ccgtcgctga agctcttcca gtgcgccgtc tgcaacaagt tcacgacgga     3540

caacctggac atgctgggcc tgcacatgaa cgtggagcgc agcctgtcgg aggacgagtg     3600

gaaggcggtg atgggggact cataccagtg caagctctgc cgctacaaca cccagctcaa     3660

ggccaacttc cagctgcact gcaagacaga caagcacgtg cagaagtacc agctggtggc     3720

ccacatcaag gagggcggca aggccaacga gtggaggctc aagtgtgtgg ccatcggcaa     3780

ccccgtgcac ctcaagtgca acgcctgtga ctactacacc aacagcctgg agaagctgcg     3840

gctgcacacg gtcaactcca ggcacgaggc cagcctgaag ttgtacaagc acctgcagca     3900

gcatgagagt ggtgtagaag gtgagagctg ctactaccac tgcgttctgt gcaactactc     3960

caccaaggcc aagctcaacc tcatccagca tgtgcgctcc atgaagcacc agcgaagcga     4020

gagcctgcga aagctgcagc ggctgcagaa gggccttcca gaggaggacg aggacctggg     4080

gcagatcttc accatccgca ggtgcccctc cacggaccca gaagaagcca ttgaagatgt     4140

tgaaggaccc agtgaaacag ctgctgatcc agaggagctt gctaaggacc aagagggcgg     4200

agcatcgtcc agccaagcag agaaggagct gacagattct cctgcaacct ccaaacgcat     4260

ctccttccca ggtagctcag agtctcccct ctcttcgaag cgaccaaaaa cagctgagga     4320

gatcaaaccg gagcagatgt accagtgtcc ctactgcaag tacagtaatg ccgatgtcaa     4380

ccggctccgg gtgcatgcca tgacgcagca ctcggtgcaa cccatgcttc gctgccccct     4440

gtgccaggac atgctcaaca acaagatcca cctccagctg cacctcaccc acctccacag     4500

cgtggcacct gactgcgtgg agaagctcat tatgacggtg accacccctg agatggtgat     4560

gccaagcagc atgttcctcc cagcagctgt tccagatcga gatgggaatt ccaatttgga     4620

agaggcagga aagcagcctg aaacctcaga ggatctggga aagaacatct tgccatccgc     4680

aagcacagag caaagcggag atttgaaacc atcccctgct gacccaggct ctgtgagaga     4740

agactcaggc ttcatctgct ggaagaaggg gtgcaaccag gttttcaaaa cttctgctgc     4800

ccttcagacg cattttaatg aagtgcatgc caagaggcct cagctgccgg tgtcagatcg     4860

ccatgtgtac aagtaccgct gtaatcagtg tagcctggcc ttcaagacca ttgaaaagtt     4920

gcagctccat tctcagtacc atgtgatcag agctgccacc atgtgctgtc tttgtcagcg     4980

cagtttccga actttccagg ctctgaagaa gcaccttgag acaagccacc tggagctgag     5040

tgaggctgac atccaacagc tttatggtgg cctgctggcc aatggggacc tcctggcaat     5100

gggagacccc actctggcag aggaccatac cataattgtt gaggaagaca aggaggaaga     5160

gagtgacttg gaagataaac agagcccaac gggcagtgac tctgggtcag tacaagaaga     5220

ctcgggctca gagccaaaga gagctctgcc tttcagaaaa ggtcccaatt ttactatgga     5280

aaagttccta gacccttctc gcccttacaa gtgtaccgtc tgcaaggaat ctttcactca     5340

aaagaatatc ctgctagtac actacaattc tgtctcccac ctgcataagt taaagagagc     5400

ccttcaagaa tcagcaaccg gtcagccaga acccaccagc agcccagaca acaaaccttt     5460

taagtgtaac acttgtaatg tggcctacag ccagagttcc actctggaga tccatatgag     5520

gtctgtgtta catcaaacca aggcccgggc agccaagctg gaggctgcaa gtggcagcag     5580

caatgggact gggaacagca gcagtatttc cttgagctcc tccacgccaa gtcctgtgag     5640

caccagtggc agtaacacct ttaccacctc caatccaagc agtgctggca ttgctccaag     5700

ctctaactta ctaagccaag tgcccactga gagtgtaggg atgccacccc tggggaatcc     5760

tattggtgcc aacattgctt ccccttcaga gcccaaagag gccaatcgga agaaactggc     5820

agatatgatt gcatccaggc agcagcaaca acagcagcag caacagcaac aacaacaaca     5880

acaacaacaa caacaagcac aaacgctggc ccaggcccag gctcaagttc aagctcacct     5940

gcagcaggag ctgcagcaac aggctgccct gatccagtct cagctgttta accccaccct     6000

ccttcctcac ttccccatga caactgagac cctgctgcaa ctacagcagc agcagcacct     6060

cctcttccct ttctacatcc ccagtgctga gttccagctt aaccccgagg tgagcttgcc     6120

agtgaccagt ggggcactga cactgactgg gacaggccca ggcctgctgg aagatctgaa     6180

ggctcaggtt caggtcccac agcagagcca tcagcagatc ttgccgcagc agcagcagaa     6240

ccaactctct atagcccaga gtcactctgc cctccttcag ccaagccagc accccgaaaa     6300

gaagaacaaa ttggtcatca aagaaaagga aaaagaaagc cagagagaga gggacagcgc     6360

cgagggggga gagggcaaca ccggtccgaa ggaaacactg ccagatgcct tgaaggccaa     6420

agagaagaaa gagttggcac cagggggtgg ttctgagcct tccatgctcc ctccacgcat     6480

tgcttcagat gccagaggga acgccaccaa ggccctgctg gagaactttg gctttgagtt     6540

ggtcatccag tataatgaga acaagcagaa ggtgcagaaa aagaatggga agactgacca     6600

gggagagaac ctggaaaagc tcgagtgtga ctcctgcggc aagttgtttt ccaacatctt     6660

gattttaaag agtcatcaag agcacgttca tcagaattac tttcctttca aacagctcga     6720

gaggtttgcc aaacagtaca gagaccacta cgataaactg tacccactga ggccccagac     6780

cccagagcca ccaccacctc cccctccacc ccctccaccc ccacttccgg cagcgccgcc     6840

tcagccggcg tccacaccag ccatccccgc atcagcccca cccatcacct cacctacaat     6900

tgcaccggcc cagccatcag tgccgctcac ccagctctcc atgccgatgg agctgcccat     6960

cttctcgccg ctgatgatgc agacgatgcc gctgcagacc ttgccggctc agctaccccc     7020

gcagctggga cctgtggagc ctctgcctgc ggacctggcc caactctacc agcatcagct     7080

caatccaacc ctgctccagc agcagaacaa gaggcctcgc accaggatca cagatgatca     7140

gctccgagtc ttgcggcaat attttgacat taacaactcc cccagtgaag agcaaataaa     7200

agagatggca gacaagtccg ggttgcccca gaaagtgatc aagcactggt tcaggaacac     7260

tctcttcaaa gagaggcagc gtaacaagga ctccccttac aacttcagta atcctcctat     7320

caccagcctg gaggagctca agattgactc ccggccccct tcgccggaac ctccaaagca     7380

ggagtactgg ggaagcaaga ggtcttcaag aacaaggttt acggactacc agctgagggt     7440

cttacaggac ttcttcgatg ccaatgctta cccaaaggat gatgaatttg agcaactctc     7500

taatttactg aaccttccaa cccgagtgat agtggtgtgg tttcagaatg cccgacagaa     7560

ggccaggaag aattatgaga atcagggaga gggcaaagat ggagagcggc gtgagcttac     7620

aaatgataga tacattcgaa caagcaactt gaactaccag tgcaaaaaat gtagcctggt     7680

gtttcagcgc atctttgatc tcatcaagca ccagaagaag ctgtgttaca aggatgagga     7740

tgaggagggg caggacgaca gccaaaatga ggattccatg gatgccatgg aaatcctgac     7800

gcctaccagc tcatcctgca gtaccccgat gccctcacag gcttacagcg ccccagcacc     7860

atcagccaat aatacagctt cctccgcttt cttgcagctt acagcggagg ctgaggaact     7920

ggccaccttc aattcaaaaa cagaggcagg cgatgagaaa ccaaagctgg cggaagctcc     7980

cagtgcacag ccaaaccaaa cccaagaaaa gcaaggacaa ccaaagccag agctgcagca     8040

gcaagagcag cccgagcaga agaccaacac tccccagcag aagctccccc agctggtgtc     8100

cctgccttcg ttgccacagc ctcctccaca agcgccccct ccacagtgcc ccttacccca     8160

gtcgagcccc agtccttccc agctctccca cctgcccctc aagcccctcc acacatcaac     8220

tcctcaacag ctcgcaaacc tacctcctca gctaatcccc taccagtgtg accagtgtaa     8280

gttggcattt ccgtcatttg agcactggca ggagcatcag cagctccact tcctgagcgc     8340

gcagaaccag ttcatccacc cccagttttt ggacaggtcc ctggatatgc ctttcatgct     8400

ctttgatccc agtaacccac tcctggccag ccagctgctc tctggggcca tacctcagat     8460

tccagcaagc tcagccactt ctccttcaac tccaacctcc acaatgaaca ctctcaagag     8520

gaagctggag gaaaaggcca gtgcaagccc tggcgaaaac gacagtggga caggaggaga     8580

agagcctcag agagacaagc gtttgagaac aaccatcaca ccggaacaac tagaaattct     8640

ctaccagaag tatctactgg attccaatcc gactcgaaag atgttggatc acattgcaca     8700

cgaggtgggc ttgaagaaac gtgtggtaca agtctggttt cagaacaccc gagctcggga     8760

aaggaaagga cagttccggg ctgtaggccc agcgcaggcc cacaggagat gccctttttg     8820

cagagcgctc ttcaaagcca agactgctct tgaggctcat atccggtccc gtcactggca     8880

tgaagccaag agagctggct acaacctaac tctgtctgcg atgctcttag actgtgatgg     8940

gggactccag atgaaaggag atatttttga cggaactagc ttttcccacc tacccccaag     9000

cagtagtgat ggtcagggtg tccccctctc acctgtgagt aaaaccatgg aattgtcacc     9060

cagaactctt ctaagccctt cctccattaa ggtggaaggg attgaagact ttgaaagccc     9120

ctccatgtcc tcagttaatc taaactttga ccaaactaag ctggacaacg atgactgttc     9180

ctctgtcaac acagcaatca cagataccac aactggagac gagggcaacg cagataacga     9240

cagtgcaacg ggaatagcaa ctgaaaccaa atcctcttct gcacccaacg aagggttgac     9300

caaagcggcc atgatggcaa tgtctgagta tgaagatcgg ttgtcatctg gtctggtcag     9360

cccggccccg agcttttata gcaaggaata tgacaatgaa ggtacagtgg actacagtga     9420

aacctcaagc cttgcagatc cctgctcccc gagtcctggt gcgagtggat ctgcaggcaa     9480

atctggtgac agcggagatc ggcctgggca gaaacgtttt cgcactcaaa tgaccaatct     9540

gcagctgaag gtcctcaagt catgctttaa tgactacagg acacccacta tgctagaatg     9600

tgaggtcctg ggcaatgaca ttggactgcc aaagagagtc gttcaggtct ggttccagaa     9660

tgcccgggca aaagaaaaga agtccaagtt aagcatggcc aagcattttg gtataaacca     9720

aacgagttat gagggaccca aaacagagtg cactttgtgt ggcatcaagt acagcgctcg     9780

gctgtctgta cgtgaccata tcttttccca acagcatatc tccaaagtta aagacaccat     9840

tggaagccag ctggacaagg agaaagaata ctttgaccca gccaccgtac gtcagttgat     9900

ggctcaacaa gagttggacc ggattaaaaa ggccaacgag gtccttggac tggcagctca     9960

gcagcaaggg atgtttgaca acacccctct tcaggccctt aaccttccta cagcatatcc    10020

agcgctccag ggcattcctc ctgtgttgct cccgggcctc aacagcccct ccttgccagg    10080

ctttactcca tccaacacag ctttaacgtc tcctaagccg aacttgatgg gtctgcccag    10140

cacaactgtt ccttcccctg gcctccccac ttctggatta ccaaataaac cgtcctcagc    10200

gtcgctgagc tccccaaccc cagcacaagc cacgatggcg atgggccctc agcaaccccc    10260

ccagcagcag cagcagcagc agcaaccaca ggtgcagcag cctcccccgc cgccagcagc    10320

ccagccgcca cccacaccac agctcccact gcaacagcag cagcaacgca aggacaaaga    10380

cagtgagaaa gtaaaggaga aggaaaaggc acacaaaggg aaaggggaac ccctgcctgt    10440

ccccaagaag gagaaaggag aggcccccac ggcaactgca gccacgatct cagccccgct    10500

gcccaccatg gagtatgcgg tagaccctgc acagctgcag gccctgcagg ccgcgttgac    10560

ttcggacccc acagcattgc tcacaagcca gttccttcct tactttgtac caggcttttc    10620

tccttattat gctccccaga tccctggcgc cctgcagagc gggtacctgc agcctatgta    10680

tggcatggaa ggcctgttcc cctacagccc tgcactgtcg caggccctga tggggctgtc    10740

cccaggctcc ctactgcagc agtaccagca ataccagcag agtctgcagg aggcaattca    10800

gcagcagcag cagcggcaac tacagcagca gcagcagcaa aaagtgcagc agcagcagcc    10860

caaagcaagc caaaccccag tcccccccgg ggctccttcc ccagacaaag accctgccaa    10920

agaatccccc aaaccagaag aacagaaaaa caccccccgt gaggtgtccc ccctcctgcc    10980

gaaactccct gaagagccag aagcagaaag caaaagtgcg gactccctct acgacccctt    11040

cattgttcca aaggtgcagt acaagttggt ctgccgcaag tgccaggcgg gcttcagcga    11100

cgaggaggca gcgaggagcc acctgaagtc cctctgcttc ttcggccagt ctgtggtgaa    11160

cctgcaagag atggtgcttc acgtccccac cggcggcggc ggcggtggca gtggcggcgg    11220

cggcggcggt ggcggcggcg gcggcggcgg cggctcgtac cactgcctgg cgtgcgagag    11280

cgcgctctgt ggggaggaag ctctgagtca acatctcgag tcggccttgc acaaacacag    11340

aacaatcacg agagcagcaa gaaacgccaa agagcaccct agtttattac ctcactctgc    11400

ctgcttcccc gatcctagca ccgcatctac ctcgcagtct gccgctcact caaacgacag    11460

cccccctccc ccgtcggccg ccgccccctc ctccgcttcc ccccacgcct ccaggaagtc    11520

ttggccgcaa gtggtctccc gggcttcggc agcgaagccc ccttcttttc ctcctctctc    11580

ctcatcttca acggttacct caagttcatg cagcacctca ggggttcagc cctcgatgcc    11640

aacagacgac tattcggagg agtctgacac ggatctcagc caaaagtccg acggaccggc    11700

gagcccggtg gagggtccca aagaccccag ctgccccaag gacagtggtc tgaccagtgt    11760

aggaacggac accttcagat tgtaagcttt gaagatgaac aatacaaaca aatgaattta    11820

aatacaaaaa ttaataacaa accaatttca aaaatagact aactgcaatt ccaaagcttc    11880

taaccaaaaa acaaaaaaaa aaaaaaaaag aaaaaaaaga aaaagcgtgg gttgttttcc    11940

catataccta tctatgccgg tgattttaca ttcttgtctt tttcttttct tttaatatta    12000

aaaaaaaaaa aaaagcccta accctgttac attgtgtcct tttgaaggta ctattggtct    12060

gggaaacaga agtccgcagg gcctccctaa tgtctttgga gcttaaaccc cttgtatatt    12120

tgcccctttt caataaacgc cccacgctga tagcacagag gagcccggca tgcactgtat    12180

gggaaagcag tccaccttgt tacagtttta aatttcttgc tatcttagca ttcagatacc    12240

aatggcttgc taaaagaaaa aaagaaatgt aatgtctttt tattctcagg tcaatcgctc    12300

acactttgtt ttcagaatca ttgttttata tattattgtt ttttcagttt tttttttttt    12360

ttttgttcca gaaaagattt tttgttttgt taacttaaaa atgggcagaa agtattcaag    12420

aaaaacaatg tgaactgctt tagctttctg gggattttta aggatagctt ttctgctgaa    12480

gccaatttca aggggaaaag ttaagcactc ccactttcaa aaaaaaaaaa aaataataac    12540

ccacacacac aaagagtgtt gaggacttgt agcttaaaaa aaataagttt taaaaactga    12600

ctttctgtat ttatgataga tatgaccatt tttggtgttg agtagattgt tgcattggaa    12660

atgaactgaa gcagtatggt agatttaaaa ggaaaaaaaa aaaaaaacct tttgtgtaca    12720

tttagctttt tgtatggtcc agctgacagc tcctcatttg atgttgtctt gttcattcct    12780

agcagatgat agattgcaat ccgttgattc gcctaagctt ttctcccctt gtcccttaat    12840

tccactttct ctttcttgtc ccttaattcc actttctctt tccttctccc acctcccgtc    12900

ctataatctc ccacttaagg tagctgcctt catttcttag agggagctgc agaattattt    12960

tataaaacta aagaaagaat ttcaagggat tctaggggtc attaggatcc tcacagatta    13020

tttttggttg gggagttgaa actttttaaa ggcatataat tctagttacc tgtgtctgtt    13080

agctttgtgc atttattttt tatttatcct tcttttggct tttttttctt tgtacccctt    13140

cttttcctcc ttgtttggta ggagcttcaa atattctttt tttttctata ctaaaggatt    13200

tgtttccatt tgtgtaattg gctgtgtact tttcttttct aaaaaaagtt tttggttagg    13260

gatttggttt ttggttttgt gtttgttttt tctttcctct ctcagaaaaa aaaatttcat    13320

gctttaaata aaatccaaag acacaccctt tcactgctga tgcagaaaaa agggaaaggg    13380

ttcttgttac ttgagaattt gtttctgatt taaacaaaca agacttagtt taataaaaga    13440

aagagaaaaa caaaagattc ccaggttgtt atgtgcttct tctgcaagca gagaggcaaa    13500

tgttaatgac aattccatat accaaaagac acatttttta cttcaaagtt ttgtccttgt    13560

gttaggcagt ctgagcagcg agtgatccag agcgcagcca acaaagcagc agatagcagt    13620

gtacagaaag caaaaaagga actgtatgtg aggcacttgt ttctgttaat atccatattc    13680

ctgttaacac acaccctttc tcatgtaaaa agaaaaataa ataaatggtc tgaactttga    13740

aaactttgtg ctgctaaaac atagattttg gagacaaata aatagatgct ttgctgtttc    13800

actttcatag ctaaacatca acagaaacca tctccccttg cccccaaagt gtgaaatcct    13860

tcttcccttc gttttcttcc ttatgtttca aaagggaact ttgaagactg tgaatacagg    13920

ttccattggt cacctttcgg gcttctttcc ccagtgctga agccactcat cgactttgca    13980

aaagactgga gcattccaag atctgaaaat ggattttttt tctttttttc ttttttagcc    14040

gggactattt tatttttatg aatttgtttt tagtttaatg aaatagtaga tcctgaaatg    14100

ttgtacatat ttctaactag gctgatgcac agtgcaaatt ccttttttaa ttgttttttt    14160

taagtagaaa tactaaagaa agaataccat ctaactattc ataccagtat ccagttgtag    14220

cataaggtgt caaaagcaag tacgcaaaac atttactgtt ttaacaagct atttcctttt    14280

aacaagaaat cttgtatttc ttcctgtgtt tgagatgaac atttttaaat tttaaagttg    14340

tacagttttt tgttttccat tattttatct tgtttgtaac tctatgaaat atatatatat    14400

atattttttg ccatttaact gttgtatgtt actctgtgtc tgtaccatat agaaaaaaaa    14460

ttgtttttgt ttttggttct ctatgtgata tcagttaaca atgtaacact agctttacct    14520

gtcaaattct gctaggtctt ctctgaaaac gttgttttta aaaatgatat tgcttggtaa    14580

tagtgcaatt tctatccttt tccctccccc ctcaactttt aagttctttt ctttataatt    14640

ttgctgcccc ctccctgatg gtttgggttt ttgtttttgt ttttgttttt ttttttcatg    14700

gagctactat gccatcctcc ctctgtgagg cagagtgact gtcagtgttt tgttatgcca    14760

tgccttgagc tgtgggtgtt tggcgacaat aaggtggttg aatagattgg ctgagcacac    14820

ttccacccac ctagtgttct cagaggggtt atgtgattgt ttcaacctgg agtgggttgc    14880

acccttaatg ctttcctctg caactaaacc gcccacatat atgttcattg aaaaaagtaa    14940

gaataattct cagcactaac ccagaagtag caaagcagtc agtgatggtg aacattagag    15000

gtcaaacatg agttagatgt ttgtgggctg acagccatcg tggctatgac cagtactatt    15060

tacaaagcat gaattcacta caatgctcaa ctgtttgttt agctttatct cacttgggga    15120

atttattcct gtctgctgca ttgtaggtag ctgggtagga tatatttcca cttgcttttt    15180

aaattagttc ttcacctcca ttgacactcg ttttttggtt ttctccctat agtgtgggtt    15240

ggtgctagac accagtctga cccacagaat gggagttatt tcatccatct ttcctccatc    15300

cttccaaaaa ccacatatct acacaaggaa aaatttaata catctaggaa tttttttttt    15360

aattacaagc tatttaaaga gatgaatgtg gccaaagttt tacacaattg aaaataaagt    15420

aaaacagacg gcatgtgttt aaacctgagt ttatcaggca tggcaggaag ttgcaggaga    15480

gagaggcagt gacccaagcc agtgcacttg atgttcatgg acatatattt tttttaaata    15540

ataaattaaa acattttaaa tagaagcata aattgagttg tttgttggcg ctgagatact    15600

gcccactgtg aaacaaagct ttgactagtt ttttgtttgt ttactttctt caggggggag    15660

gggggcaagt ttgggtagga aagaaagcat aaatgaacgt gaccctgagg tgaagaggta    15720

tatgaacagc ctttgcaatg tacaaaaaga aaaaaaaaca aaaaacaaca aaaaaaatag    15780

agcaagtgaa accaaaaatg atgttcttgg tgtttttcta taatgtagtc ttgttagctt    15840

ttttgttact gtaacaatgc tgatctcgaa ctgtaccaaa atacatggag actaacaaac    15900

agaaccacat ggaactttca aactgaaaaa aaaatttgtc acaaaaactt tgttgtcata    15960

gttaagttga ttgtagatgg taattgaata tactcctttg aaaatatttc atcaagtatg    16020

tttcctgctc attgtgatac attaaaaaaa aaatatgagc aaaa                     16064


<210>  2584
<211>  4133
<212>  DNA
<213>  homo sapiens

<400>  2584
ggcttcttgg atgggctggg cgtgcatggc ataaccgttt gagaacaaca aaccaagccg       60

gccgggctgc cgctctgttt cctgcgagga gggaagttac agatctccgc cctggcgtcc      120

ggggaaggat gggacaggct gctgagccaa ctgggtacat ggaaaactca gtctcctaca      180

gcgcaattga agacgttcag ctgctgtcct gggagaatgc cccgaagtac tgtttacagc      240

tcacgattcc tgggggaact gtcttactgc aggctgccaa tagctacctg cgagaccagt      300

ggttccattc tctgcaatgg aagaaaaaga tttacaaata taagaaagtg ctgagtaacc      360

caagccgctg ggaagttgtc ttgaaagaga tccggaccct ggtggacatg gccctgacat      420

cccccctgca ggatgactcc atcaaccagg ccccactgga aatcgtctcg aaactgctct      480

cagagaacac aaacttgacc acccaggagc atgaaaacat cattgtggca atcgctcctt      540

tgctggaaaa caaccaccca ccaccagatc tctgtgaatt cttttgcaag cactgcagag      600

agcggccccg gtccatggtg gtcatcgagg tgttcacccc cgtggtgcag cgaatcctca      660

agcataacat ggactttggg aagtgcccgc gactgaggct gtttactcag gagtacatcc      720

ttgccttgaa cgagctcaac gcggggatgg aagtggtgaa gaagttcatt cagagcatgc      780

acggccccac agggcactgc ccccaccccc gggtcctgcc caacctggtg gccgtgtgcc      840

tggctgccat ctactcctgc tatgaagagt tcatcaacag ccgcgacaat tccccaagcc      900

tgaaggaaat ccggaacggc tgccagcagc cgtgcgaccg gaagcccact ttacctctgc      960

gccttctgca ccccagcccg gacctggtgt ctcaggaagc cacgctgtct gaggcccggc     1020

tcaagtcggt ggtcgtggcc tccagtgaga tccacgtgga ggtggaacgc accagcactg     1080

ccaagccggc gctgacggcc agcgcaggca acgacagcga gcccaacctc atcgactgcc     1140

tcatggtcag ccccgcctgc agcaccatga gcatcgagct gggcccccag gccgaccgca     1200

cgctcggctg ctacgtggaa atcctcaagc tgctgtcaga ctatgatgac tggagaccgt     1260

ctctggccag tttgcttcaa cccattccat tccccaaaga agctctcgca catgagaagt     1320

tcaccaagga actgaagtac gtgattcaga ggttcgccga agaccccagg caagaggtcc     1380

actcatgcct gctgagcgtg cgggccggca aagatggctg gttccagctc tacagccccg     1440

gaggggtggc ctgcgacgat gacggggagc tgttcgccag catggtgcac atcctcatgg     1500

gctcctgtta caagaccaaa aaattcctgc tctccctggc agaaaacaag ctgggtccct     1560

gcatgctcct ggcactgagg gggaaccaga ccatggtgga gatcctgtgc ttgatgctgg     1620

aatacaacat catcgacaac aacgacaccc aactgcagat catctcaacc ctggagagca     1680

cagacgtggg gaagcgcatg tacgagcagc tgtgtgaccg gcagcgggag ctgaaggagc     1740

tgcaaaggaa aggcgggccc accaggctaa cactgccctc caagtccaca gacgctgact     1800

tggctcgttt gctgagctcc ggctccttcg gaaacctgga gaacctcagt ttggccttca     1860

ccaatgtaac cagtgcctgc gccgagcacc tcatcaaact gccttcgctc aagcagctga     1920

acctgtggtc cactcagttt ggagacgctg gccttcggct cctgtcggaa cacctcacca     1980

tgctccaggt gctgaacctg tgcgagaccc cggtcacaga cgctggcctg ctggccctga     2040

gctccatgaa gagtctctgc agtttaaaca tgaacagcac caagctctca gctgacacct     2100

acgaagatct gaaggccaag cttcccaatt tgaaggaagt ggacgtccgc tacaccgaag     2160

cctggtgaag ctcccagctc aaggcaggaa gacgtttgca accgcgacaa aataactctt     2220

gactaacagc cgcagagcag ccggtcctgg ggtcccaccc tggtgccctg gctgtgagat     2280

agatggggag tctttctggg ggcggagggg ggagggggtg gggagggggc ccacaagcac     2340

gcccagcccc cgccgaattc ttttagcttc gtaattggaa cctttgacct gatctaaagt     2400

ggactttgta gcaacaagag gagcatcagc gggtcgggga ggggtttggg ggtgggctgg     2460

ggggtggggg accctttgtg gattttcttt gcctttgtgt ttgatgccgt cgtgtgggaa     2520

aagtcaactc cgatgccacc attgcgggcc ggacgaagga tgctttcttc ctagaggctc     2580

cgagctgagc tgcgaactcg ccccccgccc ttgggacaag aagacccagt cacatcactg     2640

cacccgtcct gtgtcctcac cattgctatg caaagtgatt cttgttgtac ataagattta     2700

aataatgcac ctatttaaga catgttgaca aattgcgggt ctgggacccg cctcttattt     2760

atgaagtctt tgaccgtccc ccccgcccga ccccaccgcc ctcccgcccc cacctggcgt     2820

gtagtactgt ataaaccagt cagctgtcgg gttagtggta gtattattgt tattttttta     2880

aaggaaacaa acagacaaca aaaagaagaa aaaaaaaaag aacctccttg gaaaaattaa     2940

ttgctttttc gtaatggatt ctctatgcta atgctctctc gtctgtctgt ctgtctgccc     3000

actcccccac ccaccactgt gcgtttctga tttccaaatg tctccaactc cctcacgagg     3060

tggggctcag gctggaggag gagggattaa gatccccttg ctccactaag gcccaagctc     3120

tttctctcgg caccttttag acttgaatgg gaggctgcta acccgccctc tccagtccac     3180

cccggtaaaa gagctgttcc ccacccccag ggagctcctg tccctgtcag cctttgctgt     3240

cccctgtccc caacggagac tctgtcaccc ctgggctccc cctgccatcg tgtgcttcac     3300

gtggccccat gcatgcccgc ctctctgcat ggtctcttgg gaaaagagag atgtgtcgcc     3360

tccgccagtc cgactgccct ccccacccca cccccgccac cccccacatg tgaccactgc     3420

aacgaagaca ctccttctgt ccccacctgc tccgaagaca aaccaacctc cgtttctttt     3480

ataaacagtc ggctttttct taataagccc tcactgtaca gaacagcccg ttgatggttt     3540

atttggggtc cccctctccc cccagccctt ttttctgttg gtttagcaca aatacttccc     3600

tcctccggca cctccaaacc taccccacag tcagtgtact tgttttatat atatttaatc     3660

ttattcaatg gaaaccatgc ttttgtcgtt ttatactttg ctaggtagac tttattaccc     3720

ccccactatg ccctcatttt tttaaaaaag gaaaaaaaaa agaaactggg ttccagtctt     3780

aattcatttt ccgtgccagg ttttatttcg tgtgtgtgtg agtgtgttct gttttgtgtt     3840

ttgttttttg ttgttgtttt tagttgtttg gttttctttt ctttcccccc tccggtccca     3900

tacttcacag cactctggtg cgggaagaag cagaagcaaa aaaaataaaa ataaaaaaat     3960

aaataaaaat aaaaaaaata aaaaaggaaa aaaaaaaaag aagaaacaag acatgccacc     4020

tttcccctcg cactgttgct tttcctgatg gttaatacta ctgtcacgta gctgtgtaca     4080

aagagatgtg aaatactttc aggcaaaaat aaactgtaag tgactcatca aaa            4133


<210>  2585
<211>  7114
<212>  DNA
<213>  homo sapiens

<400>  2585
gcctccagtg actgtctcca ggatttctct cttcctattt caggaggact ctcacaggct       60

cccacagcct gtgttaagct gaggtttccc ctagatctcg tatatcccca acacatacct      120

ccacgcacac acatccccaa gaacctcgag ctcacaccaa cagacacacg cgcgcataca      180

cactcgctct cgcttgtcca tctccctccc gggggagccg gcgcgcgctc ccacctttgc      240

cgcacactcc ggcgagccga gcccgcagcg ctccaggatt ctgcggctcg gaactcggat      300

tgcagctctg aacccccatg gtggtttttt aaacacttct tttccttctc ttcctcgttt      360

tgattgcacc gtttccatct gggggctaga ggagcaaggc agcagccttc ccagccagcc      420

cttgttggct tgccatcgtc catctggctt ataaaagttt gctgagcgca gtccagaggg      480

ctgcgctgct cgtcccctcg gctggcagaa gggggtgacg ctgggcagcg gcgaggagcg      540

cgccgctgcc tctggcgggc tttcggcttg aggggcaagg tgaagagcgc accggccgtg      600

gggtttaccg agctggattt gtatgttgca ccatgccttc ttggatcggg gctgtgattc      660

ttcccctctt ggggctgctg ctctccctcc ccgccggggc ggatgtgaag gctcggagct      720

gcggagaggt ccgccaggcg tacggtgcca agggattcag cctggcggac atcccctacc      780

aggagatcgc aggggaacac ttaagaatct gtcctcagga atatacatgc tgcaccacag      840

aaatggaaga caagttaagc caacaaagca aactcgaatt tgaaaacctt gtggaagaga      900

caagccattt tgtgcgcacc acttttgtgt ccaggcataa gaaatttgac gaatttttcc      960

gagagctcct ggagaatgca gaaaagtcac taaatgatat gtttgtacgg acctatggca     1020

tgctgtacat gcagaattca gaagtcttcc aggacctctt cacagagctg aaaaggtact     1080

acactggggg taatgtgaat ctggaggaaa tgctcaatga cttttgggct cggctcctgg     1140

aacggatgtt tcagctgata aaccctcagt atcacttcag tgaagactac ctggaatgtg     1200

tgagcaaata cactgaccag ctcaagccat ttggagacgt gccccggaaa ctgaagattc     1260

aggttacccg cgccttcatt gctgccagga cctttgtcca ggggctgact gtgggcagag     1320

aagttgcaaa ccgagtttcc aaggtcagcc caaccccagg gtgtatccgt gccctcatga     1380

agatgctgta ctgcccatac tgtcgggggc ttcccactgt gaggccctgc aacaactact     1440

gtctcaacgt catgaagggc tgcttggcaa atcaggctga cctcgacaca gagtggaatc     1500

tgtttataga tgcaatgctc ttggtggcag agcgactgga ggggccattc aacattgagt     1560

cggtcatgga cccgatagat gtcaagattt ctgaagccat tatgaacatg caagaaaaca     1620

gcatgcaggt gtctgcaaag gtctttcagg gatgtggtca gcccaaacct gctccagccc     1680

tcagatctgc ccgctcagct cctgaaaatt ttaatacacg tttcaggccc tacaatcctg     1740

aggaaagacc aacaactgct gcaggcacaa gcttggaccg gctggtcaca gacataaaag     1800

agaaattgaa gctctctaaa aaggtctggt cagcattacc ctacactatc tgcaaggacg     1860

agagcgtgac agcgggcacg tccaacgagg aggaatgctg gaacgggcac agcaaagcca     1920

gatacttgcc tgagatcatg aatgatgggc tcaccaacca gatcaacaat cccgaggtgg     1980

atgtggacat cactcggcct gacactttca tcagacagca gattatggct ctccgtgtga     2040

tgaccaacaa actaaaaaac gcctacaatg gcaatgatgt caatttccag gacacaagtg     2100

atgaatccag tggctcaggg agtggcagtg ggtgcatgga tgacgtgtgt cccacggagt     2160

ttgagtttgt caccacagag gcccccgcag tggatcccga ccggagagag gtggactctt     2220

ctgcagccca gcgtggccac tccctgctct cctggtctct cacctgcatt gtcctggcac     2280

tgcagagact gtgcagataa tcttgggttt ttggtcagat gaaactgcat tttagctatc     2340

tgaatggcca actcacttct tttcttacac tcttggacaa tggaccatgc cacaaaaact     2400

taccgttttc tatgagaaga gagcagtaat gcaatctgcc tccctttttg ttttcccaaa     2460

gagtaccggg tgccagactg aactgcttcc tctttccttc agctatctgt ggggaccttg     2520

tttattctag agagaattct tactcaaatt tttcgtacca ggagattttc ttaccttcat     2580

ttgcttttat gctgcagaag taaaggaatc tcacgttgtg agggtttttt ttttctcatt     2640

taaaataaaa aaggaagaaa gaaaataatt ttccttgtaa aatcgggcca aaccccaaga     2700

cagctacatt ttcaacaaaa aagcaaacag agaaaaataa atgaacttta acactgtaag     2760

ttcagcattg acagccaact tccagtgtaa gcttttttgt gacaaatccg ggtttaaaaa     2820

tgcttatggg gagaaagctt aaagtttgtt ctaaatgtag tgaaaatgca ctgttgtctt     2880

ggaggtatca tcttgcactc taaccaaaca acaccaaatt aatctggagg tactgatact     2940

aaatttggaa tcccgtcttt aatatgagaa cacaaattac tacaactcag tacctctgtc     3000

ttactctgcc caatttcaat ttagtaatgg caccattatt cttaattccc ttaatgtctg     3060

tccgctgtat ccaattggca cagattttcc ccttcatctt caattactag tagctacccc     3120

catcaattca ccttcctcaa gagtctcaat tgaaaataat ctttgatgat acaatctctg     3180

cttttgccac aggtttgaca ttaactagac gtttctgccc ctgtgctcat taccctccca     3240

aaacaatagt ttttttaatg aattgaaaca caattagatc cattcctgag ttttcatttt     3300

taactattta ctttgtgtca gttggtttct gcatcacaag ggcattctct tacaaaacaa     3360

ctcacaacag aaaaaaaaag tcaagacaaa aaatatatat atatagtatt gacatggaga     3420

tttctttcac ttttttagtc ttagtatgat catctatttt tatatctatg tatatataaa     3480

tcacagattt taacttctta attccaagct cagggttgac acacctttgt aagaaaatgt     3540

tttgtcaacc agctcttctt gttttgtgct gctcaaagaa gggattcctc agtgatcggt     3600

gagcaccaag aatcaagaaa gagaactttt tatgtatcta actgtccatt tattaaaaat     3660

ttgccagggc acacccttct gcatgagtgt gcttcagcct gggtgctcca gactacacca     3720

aactcatggg atgagccatt ggtgtgcagg gctttaccgg tgatggaaac tgtatgtgta     3780

aagaatgtta ttcatgaaaa accattgctt tcatgtaaaa caccttcggc ctaggattcc     3840

tgcctggcac ttggatacat tacctaactc aataggccag tttagagcca cagcctaacc     3900

tgttcaccaa gtaggccaaa gccaggcctt tcgctccccc tgacagagag aagcaaaata     3960

aacccaactg ggggctttat gaatacagtt ggctatccat atgtttctta gtttttatga     4020

tgcatctgga gtagggaaaa gtaatgtttc aagacaccat agtaggccag ttacatttta     4080

attaactcat cgacagtatt gacacgtaaa tggtattttt caatctgttc tcatcaaaat     4140

taaaattagt tattgattta gtcatcacat ttaagtagaa cacatgtggc acaatagtat     4200

taagtatatt tgagcacttt tgcaagacag aaagtattta caagcatcta ttgctacttt     4260

atgcctaatg aaatataaaa tgtaggatga tgagagactt tgtggcattc tttcatttaa     4320

acctttatga aattaaccat ctagttcatc attacatact cctagaaaac catccatttc     4380

actgcccaca ttttggcttc ctaccacaaa ttccacataa gacttctcta tgaaggacca     4440

gtcatttaca ttgctcattt cattctgtgt tcagaagtca gtattgtctt tctccaataa     4500

ttaaggtgca atacaaatta aatcaacctt gattttccag actatttgaa taataacttg     4560

cttttatggc tttaaactcc aggtctttcc tttttaaaat atttctgcat tctcttttat     4620

gaactagatc aggatgcctt gtttttcctg tgctttcacc cccaaaaggt tttgtgcatg     4680

tgtatgaata cacataatat tagtgaatgt gaacccatgt tctatacgca ctaaacacac     4740

agttaatata taaacgcctg cttcatttgt ttcaacacct tcattatcaa tatgattcat     4800

attgatgaga tatagtgatg cataatgagc caggcagaga gctgaaatga tatcagttaa     4860

tgatgtcaca gtgttagcac cctgcatgga tgtggtcaaa atatcattca agttgtactt     4920

cctagttttt atcatcatac tactatgtca tatgattttc agactaattt aacatgagaa     4980

atgttttggc cctaaaggat ttcacttaac ctagttaccc tatttcagta agtattttgg     5040

aattcaaccc tcgaattatt ttttctcatt tcagcatagt gataggggat gcaatgaggc     5100

ttcattattt tttatgacct gcccctcatt tgctctgatg ttccctaaat tctgtaatca     5160

tatcataact tttgttatga atagagagga atgggctcac tgaaacctga cactagaaat     5220

tggtgggtga tgctcataac tgcaaacact tagcttattg aagtgcctct atttacatgt     5280

tctttagtta taatatgtat ttttctaaca gaaatacacg tctgtaattg gtatatatta     5340

tactttgtat gtgtcacaac aaaagctaaa cagaggctaa agtctttagc agagaagaat     5400

gaattacaaa tttaccaata agagctctgt ttatggttct gtattgaagg acaaccatga     5460

caaccttctg tcattttcac gaaggccaag ttggtacttt gattatagcc atcgtagaac     5520

attagcacta gaaatctgtc tcccttacaa tgacttacct agctagcatc aagtaacttg     5580

tatcacctgc tttaaatgta agggatagaa aatactattt tgtctacact gaaaaacatt     5640

attattcatt gataagtagt aataattata aaagtaacat tctttaaagc aaacacattg     5700

aaaatattat tacaggcaga accctgattt ttaatttata ttccctgctg cagacattag     5760

ccttctttaa ttcttttgcc attacataca tgtttcggct acagactgaa cacgaactaa     5820

agtccctaag gaggaaaaaa ccttaacata ttcctgagat gtgattcttt tattacttct     5880

ttttgcaaag ctaattatca aatgatttga ttaaacctag acgcattagg aaatgcaagt     5940

tttacctaaa acttgcagaa atttaaacac atttccattt acttactaac gaacagacct     6000

gatttttatt taaaaacaca atttagcttt gccaacagaa gagtaaagga aaccataact     6060

tataaatttg taatgtgttc ctccttgttg gagacattag ccagtgttta gttttagacc     6120

aacttataca aagagagtat tgatttgtac acattctgga gacttgctat atcatggttt     6180

gctatggcac agactcagct tagcatgggg acattttgaa cttcattcaa agttgagtag     6240

ttactggaac ctttgacatt gccttgtaat gaggtacttc caaaaaaaga cccctaacaa     6300

tggcataata gtgaggtctc tctgtgcata tacataatat atatgcagga taaatgtgtg     6360

caccaatcaa atctaaaatt ttatgtgact gtcaaatgaa tattatttgg gttaagattt     6420

ttcatttctg atttggatag aaaattgcta ttaatcttgt attaaaatag tttttaaaaa     6480

tctaccagtg ccctttctgc attttcttaa ttattgtcat agtctaaatt tcagagccat     6540

ggaatttttt gtgtttgaga catttttaga agcttcaata ttaaaaaaca acaacaaacc     6600

tcgtatatta aaacagtgcc actctcctaa gtacactcag catctgaaat caggaactat     6660

ttgaacttta gaacatttag agcttcccaa atgtgtatgg aaaatactgt agcgctgttc     6720

ttttgtactg atttcttctc agaggataaa tttagtgact tgaaaactga tgtcaatact     6780

ttataaatga ggtcagaaaa taagatcaaa tgtgaaaaga ctaataattt cccaatttag     6840

ccaattgcat tgatttttat acttctgaaa tgtttccatc ctctcaggca tgctaaatat     6900

tgtataacct gctaaagatt tatttcacaa atgcttattg aactcttatt ctctataaac     6960

cctgctctag gggatttatc actggctgtg aaaaaccacc agttgaaaat tattcattcc     7020

ttaatgcagc taatcataat tattacagat aaataatgta tttcaagaat gatcttataa     7080

ataaaggaac ccatacaaac aaaaaaaaaa aaaa                                 7114


<210>  2586
<211>  3584
<212>  DNA
<213>  homo sapiens

<400>  2586
gcaagagggc ggaacgcggg acgccaggca ccctagctcc cgacggacgc agttttcagt       60

tgcacgggcg agctccgggc cggctgcgga gcgactcccc gccgccaagt gggcggcgtg      120

gctgtcggga aagaagggct ggggcctgcc gttcttcctc ccgagtatcc cctccagctg      180

gacgacccca cgctgcagca cgggcttccg gcttctctcc tcagtggcca attcgagggc      240

acagcgggct ccggaggcgc ggcggcaagc ctatcccgcc tcccaaccac agcctccagc      300

acccgagaga acggccgccc acagcacacg ttctccggac aggagggcga aggcccaaga      360

cctggagaga tgggcagctc tcaaaaaagg cacaaacaat tgaaggatgg ataccatggc      420

atatgttaaa agcgtgttga aaggaaaata agaaagccag gaatctcagg atgaatcagt      480

ctagatcgag atcagatggt ggcagtgaag aaaccttacc tcaagaccat aatcatcatg      540

aaaatgagag aagatggcag caagagcgtc tccacagaga agaggcctat tatcagttta      600

ttaatgaact caatgatgaa gattatcggc ttatgagaga ccataatctt ttaggcaccc      660

ctggagaaat aacatcagaa gaactgcaac agcggttaga tggcgtcaag gaacaactag      720

catctcagcc tgacttgaga gatggaacga attacagaga ctcagaagtc cctagagaaa      780

gttcacatga agattctctt ctagaatggt tgaacacctt tcggcgcaca ggaaatgcaa      840

ctcgaagtgg acaaaatggg aaccaaactt ggagagctgt gagtcgaaca aacccgaaca      900

atggagagtt tcggtttagt ttggaaatcc acgtaaatca tgaaaataga ggatttgaaa      960

ttcatggaga agattataca gacattccac tttcagatag taacagagat catactgcaa     1020

ataggcaaca aaggtcaact agtcctgtgg ctaggcgaac aagaagccaa acctcagtga     1080

atttcaatgg tagtagttcc aacattccaa ggactaggct tgcttcaagg gggcaaaatc     1140

cagctgaagg atctttctca acattgggaa ggttaagaaa tggaattggg ggagcagctg     1200

gcattcctcg agctaacgct tcacgcacta atttcagtag tcacacaaac caatcaggtg     1260

gtagtgaact caggcaaagg gaggggcaac ggtttggagc agcacatgtt tgggaaaatg     1320

gggctagaag taatgttaca gtgaggaata caaaccaaag attagagcca ataagattac     1380

gatctacttc caatagtcga agccgttcac caattcagag acagagtggc actgtttatc     1440

ataattccca aagggaaagt agaccagtac agcaaaccac tagaagatct gttaggagga     1500

gaggtagaac tcgagtcttt ttagagcaag atagagaacg agaacgcaga ggtactgcat     1560

ataccccatt ctctaattca aggcttgtgt caagaataac agtagaagaa ggagaagaat     1620

ccagcagatc ctcaactgct gtacgacgac atccaacaat cacactggac cttcaagtga     1680

gaaggatccg tcctggagaa aatagagatc gggatagtat tgcaaataga actcgatcca     1740

gagtagggct agcagaaaat acagtcacta ttgaaagcaa tagtgggggc tttcgccgaa     1800

ccatttctcg tttagagcgg tcaggtattc gaacctatgt tagtaccata acagttcctc     1860

ttcgtaggat ttctgagaat gagcttgttg agccatcatc agtggctctt cggtcaattt     1920

taaggcagat catgactggg tttggagaac tgagttctct aatggaggcc gattctgagt     1980

cagaacttca aagaaatggc cagcatttac cagacatgca ctcagaactg agtaacttag     2040

gtacagataa caacaggagc cagcacaggg aaggttcctc tcaagacagg caggcccaag     2100

gagacagcac tgaaatgcat ggtgaaaacg agaccaccca gcctcatact cgaaacagtg     2160

acagtagggg tggcaggcag ttgcgaaatc caaacaattt agttgaaact ggaacactac     2220

ccattcttcg ccttgctcac ttttttttac taaatgaaag tgatgatgat gatcgaatac     2280

gtggtttaac caaagagcag attgacaatc tttccaccag gcactatgag cataacagta     2340

ttgatagtga actaggtaaa atctgtagtg tttgtattag tgactatgta actggaaaca     2400

agctcaggca attaccttgc atgcatgaat ttcacattca ttgtattgac cgatggctct     2460

cagagaattg cacttgtccg atctgtcggc agcctgtttt agggtctaac atagcaaaca     2520

atgggtaagg tgatgggatc tactcaaata ctgtttttta gtagaactga atgttcaagc     2580

attgttttgc tgagttattt gtgattagct aaccaggatg aaaaataaca gattatatat     2640

agtttgaact atttttcgtg tgctttttta aacttgttaa aaagaaattt atataaaatt     2700

taaaatacaa atgttaaatt atccagaaat acagaatagt taatattgct agaaccaaat     2760

aacctctaaa atgtttttat tttggtaatt ttgtcatgct aagcactttt gtatctgcac     2820

aattcagtag gttaagaatc aatcttcttt ttcttaatag tacagcagac tttagcttca     2880

agtttcatag gcttagtact tatatctaga catttgtgtc taaataagct tttcattaac     2940

tttttatttt aaggacagta tcttttcatg aaagagtatt tggctgaatg tttgctatat     3000

atatgttact tgaaatgtta aatttaatat gcagcatacc ataggtgtat atataggtat     3060

ataattttaa ggttaaaata ttcagtctac aagtttggtt cttatttaag cttttgggct     3120

aatactgcat atggcacaat gtttaatatt ggcaagttca tctcagagaa aggggattca     3180

gatataattt taaagtagag ataatttact gaagcgtctc tgacaatcta acttattaga     3240

cagcaagcaa tatataatac tgaaaaagta ttcagaaatg gaaaatttac atcatatagg     3300

ttatttaact tgtgttcagc ctttttgtaa cttttttgaa agtgcaaaca attctttgga     3360

ttattaaata aggtatacag tatgcatggt ttctcaaatt tagttttaaa atctaaaagt     3420

ctataaagaa tcagatgcat aggcaatatg ttaagttcac ttggaggcta aaaatctcca     3480

gtgaaaacaa aacgaaaacc tttaagagaa tgtagagttt atataaacac aaagtatgca     3540

ttgaagatct gtttctacca ataaacatta aaacaaagac tgta                      3584


<210>  2587
<211>  3559
<212>  DNA
<213>  homo sapiens

<400>  2587
ccgccgctgt cccggagcaa gccatgccgc gcttgtctct gctcttgccg ctgctgcttc       60

tgctgctgct gccgctgctg ccgccgctgt ccccgagcct tgggatccgc gacgtgggcg      120

gccggcgccc caagtgtggt ccgtgccggc cagagggctg cccggcgcct gcgccctgcc      180

cggcgcccgg gatctcggcg ctcgacgagt gcggctgctg cgcccgctgc ctgggagccg      240

agggcgcgag ctgcgggggc cgcgccggcg ggcgctgtgg ccccggcctg gtatgcgcga      300

gccaggccgc tggggcagcg cccgagggca ccgggctctg cgtgtgcgcg cagcgcggca      360

ccgtctgcgg ctccgacggt cgctcgtacc ccagcgtctg cgcgctgcgc ctgcgcgctc      420

ggcacacgcc ccgcgcgcac cccggtcacc tgcacaaggc gcgcgacggc ccttgcgagt      480

tcgctcctgt ggtcgtcgtt cctccccgaa gtgttcacaa cgtcaccggg gcgcaggtgg      540

gcctgtcctg tgaagtgagg gctgtgccta ccccagtcat cacgtggaga aaggtcacga      600

agtcccctga gggcacccaa gcactggagg agctgcctgg ggaccatgtc aatatagctg      660

tccaagtgcg agggggccct tctgaccatg aggccacggc ctggattttg atcaaccccc      720

tgcgaaagga ggatgagggt gtgtaccagt gccatgcagc caacatggtg ggagaggctg      780

agtcccacag cacagtgacg gttctagatc tgagtaaata caggagcttc cacttcccag      840

ctcccgatga ccgcatgtga tggagaaatg gtcttagaaa cattgatcat gggatgatgg      900

aaaagtcaaa taacggatct ttgtgcttca tgaagagttg gaaaacctgt gtgtgtagat      960

gacccctttt gtgtgttttt aaaaattaga tgcaaactag atctgtatgc agatgtagtt     1020

tttagcaggg caaacagtga gaaacggatt tgcatgtggc ttttttatac ttttgaaatg     1080

aattgttcca tgagaagtct ttttgtaatt attctcttcc agggagatca cagaacggca     1140

tgtttgcaat ttcgaaaggg ctcgtgtcag ctgtgactct ttacctcatt tgtctatgac     1200

ctattagtgg tgctctgtga cttagtgtgt gttgtagaag gagggatgag ggtcccagct     1260

gtcctctgcc tgactgtaac ttgctgtgtg acctgaacag atcccttccc ctctctgggc     1320

cctggtccct tcatctgtga gtatggcatt ttaactggat gttatcaatg tcccttttag     1380

ccctgccatc ctagattaag atggcctttt gggaaaataa caggaagtgt ggtcttagtg     1440

ttctttctaa aatggtattc cctcagaaac aaattccatt gctttacccc aacgtgtgga     1500

cagctggctg tagctcttct attcctaact ttttcccttt gaaggagatt tagttttagg     1560

tgggatgctt taccagactc aggagcgcct tggctgggtc tttggagacc agagcatcca     1620

tttgttagcc tagcattctc ttttttaaaa ttttattttg agacagggtc tcgctctatc     1680

acccaggctg gagtgcagtg gcgtgatcat ggctcactgc aacctccact ttctgggctc     1740

gagtgatcgt tccacctcag cctcctgagt agctgggacc acaggcatgc cccaccacac     1800

ccagctattt tttttttttt tttttttttt tttgtagaga cagggtctcc ctatgttgcc     1860

gcccaggctg gtctcaaatt cctatgctca aatgatcctc ctgccttggc ctcccaaagt     1920

gctgggatta taggcatcag ccactgtgct tggcctagcc tagcattctc taaacaggtg     1980

gttagaagcg gtggatacca ggcttctgac gatcaaattg taaaaaaagg ggtcaggtgt     2040

tatctccaga ctgtggaatt agattgtagt agaatatatt ttacctacaa acattttgac     2100

ctcacccaag agtaaggctc tctttttttt cttttttaat gaaaaaagaa aggagaatat     2160

ttgctatctt atcttaaaaa aatagatcct taggtgatta caattttaaa ataagaattg     2220

agagccctta ctatgcacag tcctttaagt tcataaagct tgatcccaac tctgggagat     2280

ggggcaggac aggtgttaat gtccctgcct ttagcagatg aagaaaccag gctctgagag     2340

gagaagctac ttgcccaagg cctgaaggcc tctgaaagag gagcagagct cagggcacct     2400

ggccctcctt ggtcccctct ctactccacg gtgctgctac tcagggtcat ctcaaaacta     2460

tgtaaaggca gatgttgcca atccacaggc ttcagggact cttatcaaga ctcatcccaa     2520

cttttaaggc acactttcac accgctcaca ttgtgcatta cattttggag tccttgttgg     2580

aagtgaactt tccgcctgta agcctgccat tccatgtcta atatattggg atggcatcac     2640

cttctgtact atgcagcaga aggagactgg cctgggattc tggaaacatg agatccattt     2700

gcatattaat ccccggctcg ctgtgtgacc ctgagcaagt ctccttcact ttctgtgcct     2760

cagtgtcctt atttgagtaa aaagggaata aaactagatg agtggttttc aaactttaaa     2820

acactggaag ctctctttga aaacaaaaga tgagaattga aatggatggc actggaagct     2880

gttcttgtct actggggttt ggagctgcca ggggacctgc tcacatccac tcctcactca     2940

gcccctcccg cccctccctt ctccacgcac tgtgactgac ttccatgtgt gaaggcctgc     3000

agttaattct cctgtgtctt gaatggttgg gagatgagtt ggtcagaccc ttagtgaaat     3060

gatgtgggaa ggaacaggaa tgctgtggct ctgaagaagg tagtagaaca tcccacacct     3120

gctaataagc acattttgca aactcagttg actcacctca gatttgccta gtgaaaactg     3180

aagggctgga tgtagaccca gagagcaggg tggacagagc ccatgctgga agtactgagc     3240

atcaggactg tatggggctg gctttagcat catcattctg tgcaaagaca aataattaat     3300

gtcacactgt ctgaaatttt caccaaaacc aaaaaggcgc attaacatga ttgttccaac     3360

ctcatggttt ttcaagtgtg agcgcccaga gacctcttca gaggctaaga gagcatgcgc     3420

tgccacagct gttagcattt ggagacgtaa ttacaatgcc cccactcccc gcaccaaacc     3480

tgggtttttc taccgttttt gtagatgtca tgatgtcacg acccctgcac cctgaaaaaa     3540

ataaatgttt ttaaggaca                                                  3559


<210>  2588
<211>  4225
<212>  DNA
<213>  homo sapiens

<400>  2588
actcttgcct cataaatcta ggattcaggg cattgttttc aatggttctc atttttggct       60

ccaaggattc tttttcatgt gactaatatt ttcggtagaa gaggaggtct ggccacgccg      120

cgggtcttgg cgagcaggtg atcacggatc cctggtgttt gctgggcgag acggtgaagc      180

aacctcctcc ccgccccctc ccccgtctag aaaggtgcaa gatccgctaa accgtgcgtt      240

gcacagcggc ggccggagca gacgcgggat ggtcgcgcgt cccctgcaca gcacagaggg      300

gcagccggag agcctgggaa agtttttgga gccgtgaggg atacagcagt ttggtcaata      360

ttgtcttaac atgcttcaaa taaatcagat gttctcagtg cagctgagtc ttggtgagca      420

gacatgggaa tccgaaggca gcagtataaa gaaggctcag caggctgttg ccaataaagc      480

tttgactgaa tctacgcttc ccaaaccagt tcagaagcca cccaaaagta atgttaacaa      540

taacccaggc agtataactc caactgtgga actgaatggg cttgctatga aaaggggaga      600

gcctgccatc tacaggccat tagatccaaa gccattccca aattatagag ctaattacaa      660

ctttcggggc atgtacaatc agaggtatca ttgcccagtg cctaagatct tttatgttca      720

gctcactgta ggaaataatg aattttttgg ggaaggaaag actcgacaag ctgctagaca      780

caatgctgca atgaaagccc tccaagcact gcagaatgaa cctattccag aaagatctcc      840

tcagaatggt gaatcaggaa aggatgtgga tgatgacaaa gatgcaaata agtctgagat      900

cagcttagtg tttgaaattg ctctgaagcg aaatatgcct gtcagttttg aggttattaa      960

agaaagtgga ccaccacata tgaaaagctt tgttactcga gtgtcagtag gagagttctc     1020

tgcagaagga gaaggaaata gcaaaaaact ctccaagaag cgcgctgcga ccaccgtctt     1080

acaggagctt aaaaaacttc cacctcttcc tgtggtggaa aagccaaaac tattttttaa     1140

aaaacgccct aaaacaatag taaaggccgg accagaatat ggccaaggga tgaaccctat     1200

tagccgcctg gcgcaaattc aacaggccaa aaaggaaaag gagccggatt atgttttgct     1260

ttcagaaaga ggaatgcctc gacgtcgaga atttgtgatg caggtgaagg taggcaatga     1320

agttgctaca ggaacaggac ctaataaaaa gatagccaaa aaaaatgctg cagaagcaat     1380

gctgttacaa cttggttata aagcatccac taatcttcag gatcaacttg agaagacagg     1440

ggaaaacaaa ggatggagtg gtccaaagcc tgggtttcct gaaccaacaa ataatactcc     1500

aaaaggaatt cttcatttgt ctcctgatgt ttatcaagag atggaagcca gccgccacaa     1560

agtaatctct ggcactactc taggctattt gtcacccaaa gatatgaacc aaccttcaag     1620

ctctttcttc agtatatctc ccacatcgaa tagttcagct acaattgcca gggaactcct     1680

tatgaatgga acatcttcta cagctgaagc cataggttta aaaggaagtt ctcctactcc     1740

cccttgttct ccagtacaac cttcaaaaca actggaatat ttagcaagga ttcaaggctt     1800

tcaggtatga attaaaagca aaaacaaaaa acaaaacaat tcattagcct cagattcttc     1860

atctgtatac atcacaaggc tcattcttgc ctgctagtat ggcctacatg ccacttacgt     1920

tttaagttat ttaggaacac aaaggacaga caaaaaagcc atatgcacat gcctcatttt     1980

ctcttatttt tgatctatct agtaattctt ttgctgcctg tctcttctcc attttccttc     2040

ttctttttta agcatttttc atattcttca ctgtcttcta tttggtcttg attaggtgca     2100

tctatctctt cgctctgtct tccacaaaca aaaattctgc cttcagacat ttggtgttag     2160

tatttcacac tcagttctcc ctttttttac ataaggattg agtttctttt tatgatgatt     2220

ttacctttat agcaattttg aattttgcat tctattgcta gtattgattc aggtacacca     2280

ttaagataca acattctaga agtctattac cttaggagtt aattaaacat gatatttgaa     2340

gaataatgaa atgctttata gttgtttgag gcataacaat gtgtatttgt tttactggat     2400

catgttttga actgactagg gagggtagca cctgcctcag atagtaccaa caattctgtt     2460

tcactgggta gtctaaaact agcttatagt ttaacttaac ttgttgtgta tgtgaattta     2520

gggatggaaa ctttttttcc cctatttatt ctttgtttcc ttctgggaaa aaaccccaca     2580

aaaatcagca ctcctttatg gatacattgg agcttttgaa agaattgtaa actctaggaa     2640

ggggaaatat ctgtgtcttg atttcttagt tgccttgaaa atcatgtact gaactgtaac     2700

cgctaacttg actggatgaa ctagtttgct tgtgtgtaga gagtgtattg cttcctcaga     2760

tttcactgtt ttcatctcct tttccatctt agtctttatt ccttaagacc aaaaactgta     2820

atatccttta gaaatgctct agaagatctg tattgtgtag aatgatcatg tatttataaa     2880

tattttacaa gtttagatta taaaatgaaa aagaaggtca tgtgttttgg ggggtatttt     2940

gcatgttcgg attttttttt cacttcaccg aacccttctg attctttcaa actattgcca     3000

ggtagttgtt agtgtttcta attggactct taatatgaac ttcaagaagc tgttaccagt     3060

tatcggctct gtcatctgaa attttaacca cttaatttaa agttacaatt ttagaatttg     3120

tttttgttgt tttaccttaa gaaacacaat aaatcactgt ttaaaaaaga tctcaattta     3180

tataaagtac tggaaaaaag ctaagtaatt tttagttcta tctataatct ccgtaggatg     3240

aattagaaat aaattgtgat gaaaagaaat taactgctta tttatgaatc taatcattta     3300

gaaatgtctg agagtaacac tgcattctta tagaaacaaa gcacaaattg cattcaagct     3360

ctgaattgat tttttgcttg gagctgttgt tacagtagct gtaattttgc taccagaatg     3420

tcttaatttt ttaaatttgt ttttatttct aagctcttgg caatgacaat aattataatt     3480

ttaacatatc ttcactgtag tcaacatgta gagtctgctt ccctcattat tgcattgcta     3540

aggccttttt aaaaagctta tgcttacata atatactctt ttttatggac acgttatatg     3600

tttccaaatc tgtgtattgt gatttttaca tactaatgaa tataaacagg tgattttaaa     3660

atattactgt gcttctttgg ttgaatgagc tggtattgat gtaaaatact ctgtcattga     3720

tggaccacta cctgcagcta agcagtgagc agaatctccg ggaaatgact tagtctggcc     3780

acatgcatag cccatcttca taatgtcgca gcagaaggtt ctttgtggtt aaaagtttta     3840

aagcctattt ctttataggt aaccctctca ggtatattta cctggtagaa aaacatgtag     3900

attgtttcta ttacttaaat gttttaattg gactgtagtt tagaaattac aggaccagct     3960

tgttacagat tatacactat tctgttactt ttatttctga aacttaaaaa caataaattc     4020

tttttctgtg tttctaggtt agaacttttt tattttattg cacactgaac agatactgtt     4080

gcttattgaa tattgtgtaa acccttcttt ggctttcctt gcccattgca atttgattta     4140

agcctactag agccattgta tgtgacagct atattgtatt acaaagtaaa aatatatgag     4200

tgtattgaaa acaaaaaaaa aaaaa                                           4225


<210>  2589
<211>  2527
<212>  DNA
<213>  homo sapiens

<400>  2589
gcacgggctg gtctctgccc taatgcggcg gctggcggcg agaggcgctg caggggacgc       60

gggggaagtg gcggcgccgg cagcggacag ctcggacagc gcccagggcc ggagcccgag      120

cccttggagg ttgattgact tatgtgcaat ttgggacgct ggagtttacc ttccctccgc      180

agcctggaac agagcctcct ctggtgttgc aaggaagagg ctgaatgagg cagagaagct      240

gagtgctgtc caggaggccc agttaaagcg gctcgaggtg acaagacccc gagtgctggg      300

gagcagggag cagggccagg tgccgaggat ggccaggcag ccaccgccgc cctgggtcca      360

tgcagccttc ctcctctgcc tcctcagtct tggcggagcc atcgaaattc ctatggatcc      420

aagcattcag aatgagctga cgcagccgcc aaccatcacc aagcagtcag cgaaggatca      480

catcgtggac ccccgtgata acatcctgat tgagtgtgaa gcaaaaggga accctgcccc      540

cagcttccac tggacacgaa acagcagatt cttcaacatc gccaaggacc cccgggtgtc      600

catgaggagg aggtctggga ccctggtgat tgacttccgc agtggcgggc ggccggagga      660

atatgagggg gaatatcagt gcttcgcccg caacaaattt ggcacggccc tgtccaatag      720

gatccgcctg caggtgtcta aatctcctct gtggcccaag gaaaacctag accctgtcgt      780

ggtccaagag ggcgctcctt tgacgctcca gtgcaacccc ccgcctggac ttccatcccc      840

ggtcatcttc tggatgagca gctccatgga gcccatcacc caagacaaac gtgtctctca      900

gggccataac ggagacctat acttctccaa cgtgatgctg caggacatgc agaccgacta      960

cagttgtaac gcccgcttcc acttcaccca caccatccag cagaagaacc ctttcaccct     1020

caaggtcctc accacccgag gagttgcaga aagaacacca agcttcatgt atccccaggg     1080

caccgcgagc agccagatgg tgcttcgtgg catggacctc ctgctggaat gcatcgcctc     1140

cggggtccca acaccagaca tcgcatggta caagaaaggt ggggacctcc catctgataa     1200

ggccaagttt gagaacttta ataaggccct gcgtatcaca aatgtctctg aggaagactc     1260

cggggagtat ttctgcctgg cctccaacaa gatgggcagc atccggcaca cgatctcggt     1320

gagagtaaag gctgctccct actggctgga cgaacccaag aaccttattc tggctcctgg     1380

cgaggatggg agactggtgt gtcgagccaa tggaaacccc aaacccactg tccagtggat     1440

ggtgaatggg gaacctttgc aatcggcacc acctaaccca aaccgtgagg tggccggaga     1500

caccatcatc ttccgggaca cccagatcag cagcagggct gtgtaccagt gcaacacctc     1560

caacgagcat ggctacctgc tggccaacgc ctttgtcagt gtgctggatg tgccgcctcg     1620

gatgctgtcg ccccggaacc agctcattcg agtgattctt tacaaccgga cgcggctgga     1680

ctgccctttc tttgggtctc ccatccccac actgcgatgg tttaagaatg ggcaaggaag     1740

caacctggat ggtggcaact accatgttta tgagaacggc agtctggaaa ttaagatgat     1800

ccgcaaagag gaccagggca tctacacctg tgtcgccacc aacatcctgg gcaaagctga     1860

aaaccaagtc cgcctggagg tcaaagaccc caccaggatc taccggatgc ccgaggacca     1920

ggtggccaga aggggcacca cggtgcagct ggagtgtcgg gtgaagcacg acccctccct     1980

gaaactcacc gtctcctggc tgaaggatga cgagccgctc tatattggaa acaggatgaa     2040

gaaggaagac gactccctga ccatctttgg ggtggcagag cgggaccagg gcagttacac     2100

gtgtgtcgcc agcaccgagc tagaccaaga cctggccaag gcctacctca ccgtgctagg     2160

taactgccca tgctcaccct ggcactgacc agccccaccc cctccccagc agccagagaa     2220

gcagtggccc ggggcagttc cgagggcagt gcctgcagtc aagtggccgg gtcaggcgtg     2280

gtgatctctt cttgcctcgt gatgtcaggg ttagggagct gccagtttca gaacaagctg     2340

tgctggacag gttacctcct gagtggagtc attaacttcc ccacgtctca actgaaaggg     2400

gcctgagtga tatagagaaa gtggagaggg gtttctcgtt gtgatcattt tacctttctt     2460

acagctaact ccaccactaa gtcaattaaa acaatccatc cttaaagcaa aaaaaaaaaa     2520

aaaaaaa                                                               2527


<210>  2590
<211>  2418
<212>  DNA
<213>  homo sapiens

<400>  2590
ggccacacgc gcgcacccac ccgcgcgcac ccagcccccg ggagaggcag gaagggaggc       60

ggcggcgcga ggaggaggga gcggccgtgg agcccaatcg ttcgctcccc ttcccgggtc      120

cgcgcgcggc gccgcctccg ccattgctgc gagcaggagc aggagacgcg gagctcggag      180

cgctgagctg acctgccgga gccgggcgtg ggctgcagcc tcggagctcc cggaacgatg      240

gtgaagttgg ggaacaattt cgcagagaag ggcaccaagc agccgctgct ggaggatggc      300

ttcgacacca ttcccctgat gacgcccctc gatgtcaatc agctgcagtt cccgcccccg      360

gataaggtgg tcgtgaaaac taagaccgag tatgaacctg accgcaagaa agggaaagca      420

cgtcctcccc aaattgctga gttcaccgtc agcatcacgg agggtgtcac cgagaggttt      480

aaggtctccg tgttggtcct cttcgccctg gccttcctca cctgcgtcgt cttcctggtt      540

gtctacaagg tgtacaagta tgaccgcgcc tgccccgatg ggttcgtcct caagaacacc      600

cagtgcatcc cagaaggctt ggagagctac tacgcggagc aagactccag tgcccgggag      660

aaattttaca cagtcataaa ccactacaac ctggccaagc agagcatcac gcgctccgta      720

tcgccctgga tgtcagttct gtcagaagag aagctgtccg agcaggagac tgaagcggct      780

gagaagtcag cttagcggga tgggcaagtt ccttacaatg tgtcacttgc aaataacaaa      840

gggactttga gggacatttc attaaatata attactgata ctttagaggt tactcattta      900

cggtgcaatt gcttctgttt gctaatgctg ctttgcaaat aaaacttgct gccgaccacc      960

cacgggcata aaatcaagtg catttcagca ttgcctaaag agctctgaca ccacttttca     1020

tgttaagatc ttcatttagc tcctttactg ggatttattg gatgctgtaa aaaaataaat     1080

ttacactgga tatgcgaagg gtttggatct cagataaatg cattttgtgg aattgatttt     1140

ctgaaccgac cctgctgtct gcaaaccttc ctccatagcc atatctagag tgatctctcg     1200

ctgtgctaag agcaagccta cttcgcattt cttcctcggc catcagcggg taacagtgct     1260

gactgctgcc aaggtgcact gtagtaagta agtggcatag agaacgagga aaaagacccc     1320

cccacccctc cctgtgctga ctcctgagtc ggggtgggac ggccctgcaa tgtggcaggc     1380

tcggtgtgga ttgactactc cctcccctct gactctggca tcttggtaag gagggagggg     1440

caccacccat ctgggtggag acagctgggg tttgctccag tgtgtgtaga ctggcagagc     1500

atgtgaggga gagggctggg aagagacggc cctgggcccg tgaggtgcag aactctccct     1560

gcaggtagtc tgtctgctct gtgatgtgct gataggaaag agcccccact ggccctctgg     1620

ttcacttcta ttatgaataa atttgcacca atagccccat tagtttttaa agaaatgagc     1680

tgggtgggaa aagtggaaat gtaatttctg gtaagcttga gctactttaa tttttattct     1740

atgaaactga tatcccttga tgtgggaaac aggcaggaaa ggctgtgggg tgggggtggg     1800

ggactggtgt ggcaccgtgc aaacaaaatg acaaatttca actcacaatc tttgtaagaa     1860

aattgttcca gtttgaatct tgatattaaa gtttatgttt acaaaactgc cagttagatg     1920

aactaagtgt gtaaaacaaa tagaaaagac attcgcagac atttcttcta tgttattgaa     1980

tgtgttgttt ctggtgtacg tgtcaaaagt ttcagttttt tagatcagaa ataaacgaca     2040

aatagtgtga gatgtgttgt gaacaggcat ggtgaccgtg gtcagcgcca ctcttgtttc     2100

ctgaaatgtg cttctaagac agaaaatgta ttttctcatc aagggtgtct ggagacacag     2160

accgtgacct tggcgcagcg gtgtgcatca gaggcgtgtg ctgagaaggg tggtgttaag     2220

ctgtggaaaa tgactcaaga gcaataaatc agtgccaaag cttccctgcg catctgaata     2280

gacacaagtg aagcccgtgt gcgcacagtg cagaggccga gcctgtattt ccaggtagac     2340

gtggacttta ttgactgtga attcatttac atgtaacttc tgacatttca ctctgtgcaa     2400

ataaagaaca tgaggata                                                   2418


<210>  2591
<211>  564
<212>  DNA
<213>  homo sapiens

<400>  2591
attcttcccc tctctacaac cctctctcct cagcgcttct tctttcttgg tttggtgctt       60

ctgagatgtg ggcttgcaca cgctgttgct atagtacgtg ttgatcctga ctgctgtcat      120

ggcgtgccct ctggagaagg ccctggatgt gatggtgtcc accttccaca agtactcggg      180

caaagagggt gacaagttca agctcaacaa gtcagaacta aaggagctgc tgacccggga      240

gctgcccagc ttcttgggga aaaggacaga tgaagctgct ttccagaagc tgatgagcaa      300

cttggacagc aacagggaca acgaggtgga cttccaagag tactgtgtct tcctgtcctg      360

catcgccatg atgtgtaacg aattctttga aggcttccca gataagcagc ccaggaagaa      420

atgaaaactc ctctgatgtg gttggggggt ctgccagctg gggccctccc tgtcgccagt      480

gggcactttt ttttttccac cctggctcct tcagacacgt gcttgatgct gagcaagttc      540

aataaagatt cttggaagtt ttga                                             564


<210>  2592
<211>  2498
<212>  DNA
<213>  homo sapiens

<400>  2592
tttttttttt tttttttttt ggaaagcaag gatcacactt ccccctccct gttccttaat       60

cccttttcta aaaagggggg aaaatccgga tggattttag ggattggtct ggtgtcagct      120

gtgttttatt gcacacctaa atcctgatta taggcttttc atttctccgc aaagccttta      180

ttttggcagt taagccaaat gtgttttcca gaaagttagt tattttctcc tctttctttc      240

ctttctttcc tccctttttc ccgtctgacc ccaaacgtta ttgtccaaac atgactggac      300

agcagctttt gtttcttgac cctgtaatat gacagtctgc taatattgac agaaggtgca      360

gtttttgggt tatagtcgtg attttcgcta atcaatcata ttagcaggaa aaaaaatgac      420

ttgtttctgt tgtacttgag tcttaagaaa aagtgcccat agtttagtga caatttccaa      480

aggctttagt accacctgta tttcaaaatg ggggacccaa actcccggaa gaaacaagct      540

ctgaacagac tacgtgctca gcttagaaag aaaaaagaat ctctagctga ccagtttgac      600

ttcaagatgt atattgcctt tgtattcaag gagaagaaga aaaagtcagc actttttgaa      660

gtgtctgagg ttataccagt catgacaaat aattatgaag aaaatatcct gaaaggtgtg      720

cgagattcca gctattcctt ggaaagttcc ctagagcttt tacagaagga tgtggtacag      780

ctccatgctc ctcgatatca gtctatgaga agggatgtaa ttggctgtac tcaggagatg      840

gatttcattc tttggcctcg gaatgatatt gaaaaaatcg tctgtctcct gttttctagg      900

tggaaagaat ctgatgagcc ttttaggcct gttcaggcca aatttgagtt tcatcatggt      960

gactatgaaa aacagtttct gcatgtactg agccgcaagg acaagactgg aatcgttgtc     1020

aacaatccta accagtcagt gtttctcttc attgacagac agcacttgca gactccaaaa     1080

aacaaagcta caatcttcaa gttatgcagc atctgcctct acctgccaca ggaacagctc     1140

acccactggg cagttggcac catagaggat cacctccgtc cttatatgcc agagtagagt     1200

actgaccagc aaaatggaga agatcagaga atgcagcagc agtttttttt cttgttttct     1260

taccacttta ttctttcaga gtttaaagaa aatggactca tgcacagaac actatgcatt     1320

ttgaaacttg ttcatcctgg atttttttaa atcattttta tctcagaact taaacaaaaa     1380

ttagatgtcg tgcacggact gtgtgaaaga agatgctttg catatttgct gcactgcatc     1440

agtatcttac taaaaatgtg aaatgaaagg actattgtac actgaaatgc ttaaatgtat     1500

ctgaaagcac aaggtgatac tcatttttat ggtcttccca tttgtgctgg tttttgcctc     1560

tttgacatct gtcatcagta tttagagggt gagaagtgaa tgtaacaggt ataaataaca     1620

tttttaaaaa caataacttt gctataatca cagttgttcc agagcactgt cagatacatt     1680

ctaatgacca gaactggttt aaaaaaagaa aatacaacca tgggaaagaa atcttaaatg     1740

aaaaacgcat ctcattgtag gcatttttgc ctcatatttt actgggccat gtttgtttcc     1800

tggtactcat gtattttttt tttccagatc tctttcccca agttgctatt gtaagagtat     1860

tctgctgcgt gtggatgcag ttatacacat taaagcagat ctggagtctg aagtagctat     1920

aaagcagcta taaaacagaa atacatgcat agctgcagaa accatgatag gtagaggact     1980

tttcttttgg ttttgttttg ttttgttttg ttttgttttt ggttttacag agaagagatt     2040

tttattacaa agaaaaaaat tccagtgaat tgtgcagaaa tgctggtttt tacaccatcc     2100

taaagaaaaa ctttacaagg gtgttttgga gtagaaaaaa ggttataaag ttggaatctt     2160

aaattgtaaa attaaccatt gagtgtcaaa gttctaaaag cagaactcat tttgtgcaat     2220

gaacataagg aaagactact gtataggttt tttttttttt ctccttttaa atgaagaaaa     2280

gctttgctta agggttgcat acttttattg gagtaaatct gaatgatcct actcctttgg     2340

agtaaaacta gtgcttacca gtttccaatt gtatttagct tctggttgga atttgaaaaa     2400

aaaagaaaaa aagaaaaaga aaacctaaat aaaataggtg aaagttccct gactattcag     2460

gtgaatacac aaaaaaaaaa aaaaaaaaaa aaaaaaaa                             2498


<210>  2593
<211>  2498
<212>  DNA
<213>  homo sapiens

<400>  2593
tttttttttt tttttttttt ggaaagcaag gatcacactt ccccctccct gttccttaat       60

cccttttcta aaaagggggg aaaatccgga tggattttag ggattggtct ggtgtcagct      120

gtgttttatt gcacacctaa atcctgatta taggcttttc atttctccgc aaagccttta      180

ttttggcagt taagccaaat gtgttttcca gaaagttagt tattttctcc tctttctttc      240

ctttctttcc tccctttttc ccgtctgacc ccaaacgtta ttgtccaaac atgactggac      300

agcagctttt gtttcttgac cctgtaatat gacagtctgc taatattgac agaaggtgca      360

gtttttgggt tatagtcgtg attttcgcta atcaatcata ttagcaggaa aaaaaatgac      420

ttgtttctgt tgtacttgag tcttaagaaa aagtgcccat agtttagtga caatttccaa      480

aggctttagt accacctgta tttcaaaatg ggggacccaa actcccggaa gaaacaagct      540

ctgaacagac tacgtgctca gcttagaaag aaaaaagaat ctctagctga ccagtttgac      600

ttcaagatgt atattgcctt tgtattcaag gagaagaaga aaaagtcagc actttttgaa      660

gtgtctgagg ttataccagt catgacaaat aattatgaag aaaatatcct gaaaggtgtg      720

cgagattcca gctattcctt ggaaagttcc ctagagcttt tacagaagga tgtggtacag      780

ctccatgctc ctcgatatca gtctatgaga agggatgtaa ttggctgtac tcaggagatg      840

gatttcattc tttggcctcg gaatgatatt gaaaaaatcg tctgtctcct gttttctagg      900

tggaaagaat ctgatgagcc ttttaggcct gttcaggcca aatttgagtt tcatcatggt      960

gactatgaaa aacagtttct gcatgtactg agccgcaagg acaagactgg aatcgttgtc     1020

aacaatccta accagtcagt gtttctcttc attgacagac agcacttgca gactccaaaa     1080

aacaaagcta caatcttcaa gttatgcagc atctgcctct acctgccaca ggaacagctc     1140

acccactggg cagttggcac catagaggat cacctccgtc cttatatgcc agagtagagt     1200

actgaccagc aaaatggaga agatcagaga atgcagcagc agtttttttt cttgttttct     1260

taccacttta ttctttcaga gtttaaagaa aatggactca tgcacagaac actatgcatt     1320

ttgaaacttg ttcatcctgg atttttttaa atcattttta tctcagaact taaacaaaaa     1380

ttagatgtcg tgcacggact gtgtgaaaga agatgctttg catatttgct gcactgcatc     1440

agtatcttac taaaaatgtg aaatgaaagg actattgtac actgaaatgc ttaaatgtat     1500

ctgaaagcac aaggtgatac tcatttttat ggtcttccca tttgtgctgg tttttgcctc     1560

tttgacatct gtcatcagta tttagagggt gagaagtgaa tgtaacaggt ataaataaca     1620

tttttaaaaa caataacttt gctataatca cagttgttcc agagcactgt cagatacatt     1680

ctaatgacca gaactggttt aaaaaaagaa aatacaacca tgggaaagaa atcttaaatg     1740

aaaaacgcat ctcattgtag gcatttttgc ctcatatttt actgggccat gtttgtttcc     1800

tggtactcat gtattttttt tttccagatc tctttcccca agttgctatt gtaagagtat     1860

tctgctgcgt gtggatgcag ttatacacat taaagcagat ctggagtctg aagtagctat     1920

aaagcagcta taaaacagaa atacatgcat agctgcagaa accatgatag gtagaggact     1980

tttcttttgg ttttgttttg ttttgttttg ttttgttttt ggttttacag agaagagatt     2040

tttattacaa agaaaaaaat tccagtgaat tgtgcagaaa tgctggtttt tacaccatcc     2100

taaagaaaaa ctttacaagg gtgttttgga gtagaaaaaa ggttataaag ttggaatctt     2160

aaattgtaaa attaaccatt gagtgtcaaa gttctaaaag cagaactcat tttgtgcaat     2220

gaacataagg aaagactact gtataggttt tttttttttt ctccttttaa atgaagaaaa     2280

gctttgctta agggttgcat acttttattg gagtaaatct gaatgatcct actcctttgg     2340

agtaaaacta gtgcttacca gtttccaatt gtatttagct tctggttgga atttgaaaaa     2400

aaaagaaaaa aagaaaaaga aaacctaaat aaaataggtg aaagttccct gactattcag     2460

gtgaatacac aaaaaaaaaa aaaaaaaaaa aaaaaaaa                             2498


<210>  2594
<211>  3077
<212>  DNA
<213>  homo sapiens

<400>  2594
gcgcactcag caggttgggc tgcggcggcg gcggctgggg aagccgaagc gccgcgcgtg       60

agagatcccg gatacatctg cggtttgggc tccgccaccc tccgtctctc tcccgcaggt      120

ctctgagccg ggtgcggaag gagggaacgg ccctagcctt gggaagccaa agcacacccc      180

tggctcctgc cgacaccgcc ctccttccct tcccagccgc gggcctcgct ccgtgctcgg      240

ctactctgcc gggaggcggc ggcggctgcc agtctgtggc gagccctgct gccctccagc      300

cgggctcctc cagccgggct cctccaccgg cccttgcagg ggcgcagaga gctcggcgcc      360

cgcccttccg ctcgcctttt tcgtcagccg gctggaggag catcggtccg ggaggtctct      420

gggctgaggc ggcgacagct cctctagttc caccatgtcc gcgggcggag acttcgggaa      480

tccgctgagg aaattcaagc tggtgttcct gggggagcaa agcgttgcaa agacatcttt      540

gatcaccaga ttcaggtatg acagttttga caacacctat caggcaataa ttggcattga      600

ctttttatca aaaactatgt acttggagga tggaacaatc gggcttcggc tgtgggatac      660

ggcgggtcag gaacgtctcc gtagcctcat tcccaggtac atccgtgatt ctgctgcagc      720

tgtagtagtt tacgatatca caaatgttaa ctcattccag caaactacaa agtggattga      780

tgatgtcaga acagaaagag gaagtgatgt tatcatcacg ctagtaggaa atagaacaga      840

tcttgctgac aagaggcaag tgtcagttga ggagggagag aggaaagcca aagggctgaa      900

tgttacgttt attgaaacta gggcaaaagc tggatacaat gtaaagcagc tctttcgacg      960

tgtagcagca gctttgccgg gaatggaaag cacacaggac ggaagcagag aagacatgag     1020

tgacataaaa ctggaaaagc ctcaggagca aacagtcagc gaagggggtt gttcctgcta     1080

ctctcccatg tcatcttcaa cccttcctca gaagccccct tactctttca ttgactgcag     1140

tgtgaatatt ggcttgaacc ttttcccttc attaataacg ttttgcaatt catcattgct     1200

gcctgtctcg tggaggtgat ctattagctt cacaagcaca aaaaaagtca gcgtcttcat     1260

tatttatatt ttacaaaaag ccaaattatt tcagcatatt ccggtgataa ctttaaaaat     1320

tagatacatt ttcttaacat ttttttcttt tttaatgtta tgataatgta cttcaaaatg     1380

atggaaatct caacagtatg agtatggctt ggttaacgag cagtatgttc acagcctgct     1440

ttatctctcc ttgctcttct cacctctccc ttaccccgtt ccctatttcc gtgttcttac     1500

ctagcctccc cccacttcct caaaacaaac aagagatggc aaagcagcag tccgaccaag     1560

cccactggaa ttatccttta attttacaga taccacttgc tgtaggctgt ggaccaagat     1620

gtccagaatt attcttgagc actgatgtaa attacttaga tcttctttga ggtcagaatt     1680

cagcgatcac ggtaggcagt gcttgaatga gaaaagcctc ctggtgcatc ttcaaaatga     1740

gtcctaaaga acatactgag tacttataag tagcagaaca taaaatgtat ttctgactaa     1800

cacaaatggt cctttcacat gtgctttatt agactctggg agagaaaagt aaccaagtgc     1860

ttcagaacag gtttttagta tttacttctt catggtaaga taatgaagtt ctaatgaact     1920

atttctccca aggttttaaa attgtcaaga gttattctgt ttgtttaaaa agtaagaaac     1980

ctctgtaagc aatagatttt gcttgggttt tctttcttaa aaaaataata ctatgcaggc     2040

aagacaccat aaaagtttaa ttccttacag aagaaccagt ggaagaattt aaatttggca     2100

ctacgatcaa aactactgaa ttagcagaaa taacgatatc taaagcttac cagcaaaaga     2160

accctcagca gaatagcaaa aactttgctc aggacatttg aggtcaaatt gaagacggaa     2220

gacggaagac ggaaaccgga aaccgttttc ttgtaagccc ctagaggcag atcaggtaaa     2280

gcatacatag tagagggaaa ggagagaatg gaaataaaac tgaatattat gcagatttat     2340

gccttatttt ttagcatttt ttaaggttgg gtctttcagg ctggttttgg tttgtattag     2400

atctgtatag tttaactagt gatttagttt tatatttaag ctacgattaa tattttttct     2460

ttggcgatat ttctttgctt tttttttttt taacaacttt ccatttttag atgtttcgtt     2520

gaatctattt agagcttcac catggcaata tgtatttccc ttaaaacact gcaaacaaat     2580

atactaggag tgtgcccttt taatctttac tagttattgt gagattgctg tgtaagctaa     2640

taaacacatt tgtaaataca ttgtttgcag gaagaaaact tcgagttaca ggtcaggaaa     2700

agcctgctga atttatgttg taaacgttac ttaacacagt ataaagatga aaagacaaca     2760

aaagtatctt catacttcct catcccctca ttgcaacaaa accttaaact gggagaacct     2820

tagtcccctc tctttcctct tcctcctcca cttcccactt attgtcactt tgtaatattc     2880

agagagcact tggattatgg atctgaatag agaaatgctt acagataatc attagcccac     2940

ataccagtaa cttatactta aagatgggat ggagttataa agtgctttta taatacaata     3000

taattgctaa aggcaagggt tgactctttg ttttattttg acatggcatg tcctgaaata     3060

aatattgatt cactatg                                                    3077


<210>  2595
<211>  3777
<212>  DNA
<213>  homo sapiens

<400>  2595
gtctttacgt agacgtcggg ggcgcagccg cgctgtgcgc ggtgactggc ggctgcactg       60

gcggcagctg gaggtgtaat agtgcgggta gtgggtttgg agaagttccg aggcggcggt      120

ggcgccggtc aggacaagga tagcggaacc gggccctggg cttgtcgctc accatgccga      180

cagtagagga gctttaccgc aattatggca tcctggccga tgccacggag caagtgggcc      240

agcataaaga tgcctatcaa gtgatattgg atggtgtgaa aggtggtact aaggaaaagc      300

gattagcagc tcaatttatt ccgaaattct ttaagcattt tccagaattg gctgattctg      360

ctatcaatgc acagttagac ctctgtgagg atgaagatgt atctattcga cgtcaagcaa      420

ttaaagaact gcctcaattt gccactggag aaaatcttcc tcgagtggca gatatactaa      480

cgcaactttt gcagacagat gactctgcag aatttaacct agtgaacaat gccctattaa      540

gtatatttaa aatggatgca aaagggactt taggtgggtt gttcagccaa atacttcaag      600

gagaggacat tgttagagaa cgagcaatta aattcctttc tacaaaactt aagactttac      660

cagatgaagt cttaacaaag gaagtggaag agcttatact aactgaatcc aaaaaggtcc      720

tagaagatgt gactggtgaa gaatttgttc tatttatgaa gatactgtct gggttaaaaa      780

gcttacagac agtgagtgga agacagcaac ttgtagagtt ggtggctgaa caggccgacc      840

tagaacagac cttcaatccc tcggatcctg actgtgtgga caggctctta cagtgcactc      900

ggcaggcagt acccctcttc tctaaaaatg tccattccac aaggtttgtg acatatttct      960

gtgagcaggt tctccctaac ctcggtacct tgactacccc agtggaaggt cttgatatac     1020

agttggaggt attgaaattg ttggcggaga tgagttcatt ttgtggtgac atggaaaaac     1080

tagaaacaaa tttaaggaaa ctatttgata agttattgga atacatgccc ctccctccag     1140

aagaggcaga aaatggagag aatgctggta atgaagaacc caagctacag ttcagttatg     1200

tggaatgttt gttgtacagt tttcaccagt tgggccgaaa acttccagat ttcttaacag     1260

ccaaactgaa tgcagaaaag ctcaaagatt tcaaaatcag gctgcagtac tttgcacggg     1320

gcctgcaagt ttatatcaga caacttcgct tagctctcca gggtaaaacg ggtgaggcct     1380

taaaaacaga agagaacaag attaaagtcg ttgcattgaa aataacaaac aatatcaatg     1440

ttttaatcaa ggatctcttc cacattcctc cttcttataa gagcacagta acactatcct     1500

ggaaacctgt acaaaaggtt gagattgggc aaaagagagc cagtgaagat acaacttcag     1560

gttcaccacc caagaaatct tcagcaggac caaaaagaga tgccaggcag atttataacc     1620

ctcccagtgg gaaatatagc agcaatttgg gcaactttaa ttatgagagg agccttcagg     1680

ggaagtagag gtggccgagg ttggggcaca cgaggaaatc gtagtcgggg aagactctac     1740

tgaataagac atcagcattc ttcagcattg tcatgagctt aatatactta aattctacta     1800

ctcattggat tgccggggat gtccctttaa acagactgct gccttcagct aaaaacttaa     1860

tgttctttat acctttgtat gtatgaccta cttttgtaac agaccatggt tgtgtccaag     1920

gtaaaaccac agtgatattt ttggatgctt tgtctgcaat cttgacttgt ttttgcagta     1980

tcattattca gacttcaaat tgtgaatctt ttaaacatct tgataatttg ttgttgagag     2040

ctgttcattc taaaatgtaa tgaaattcag tctagttctg ctgataaaga tcatcagttt     2100

tgaaaggtta ctgattttcc tcttccctct tagtttttta cccaatatat ggagaagagt     2160

aatggtcaat cttaacattt tgttttaatt gtttaataaa gctgctgggc agtggtgcag     2220

cattcctacc tagtgtcata aaagcaaaat acttacatag ctttcttaaa atataggaat     2280

gacattacat ttttaggaga aagtaagttg ctttgcaccg cctacttaat tcttttccat     2340

atattgtgat acaaactttt gaatatggaa tcttactatt tgaatagaaa tgtgtatgta     2400

taatatacat acatacataa gcatatatgt gtgtgtgtgt gtgtatatat atatatatgc     2460

atgctgtgaa acttgactac acaacataaa tcacttttta aattccagga acgggtagtc     2520

tgacacggtg attatccttt tgaggctgaa tccgttatta acttgttatt taggttttta     2580

ctcccagtag caagggattc taagttagtt gcacttacat gattattgtt atttaaaact     2640

aagaataaag gctgcatttt caaagataaa ttggaattgc tgttggtgaa ataacaacca     2700

aaatactgaa tctgatgtac atacaggttt ctacaggaag agatggtata atttacaatt     2760

tggagattta ataaccaggg ctacccagaa aaagtgactt gataacatgg taccaataag     2820

taagggatgc tctctcggtt tgcttttgcc actttcaaga ttttaacttc tcaggttatt     2880

aatcaaaatt attgtataag ttagccaata gaatttttag gttaaaacaa cagatggggg     2940

gtttgtggag tgtttaatgt catgggcatt tttagtagca tagacccttt gttctgcatt     3000

tgaatgtttc gtatattttt gtttcacagt taatcttccc tccccaagtt tgctattcaa     3060

atcaactgcc tgaatgacat ttctagtagt ctgatgtatt tttctgagga atagtttgtg     3120

attccaatgc aggtgtcttc attaccatta cctctacact gcagaagaag caaaactcct     3180

ttattagaat tactgcacat gtgtatgggg aaaatagttc tgaaaggcta gaatgataca     3240

agtgagcaaa agttggtcag cttggctatg gagtggtggc aataatctct aaacattcca     3300

aaagaccatg agctgaacct aaactccctt ggaatctgaa caaaggaata taaaattgcc     3360

atttgaaaac tgaccagcta atctggacct cagagataga tcagccagtg gcccaaagcc     3420

atttcaagta cagaaattat agagactaca gctaaataaa tttgaacatt aaatataatt     3480

ttaccacttt ttgtctttat aagcatattt gtaaactcag aactgagcag aagtgacttt     3540

actttctcaa gtttgatact gagttgactg ttcccttatc cctcaccctt ccccttccct     3600

ttcctaaggc aatagtgcac aacttaggtt atttttgctt ccgaatttga atgaaaaact     3660

taatgccatg gatttttttc ttttgcaaga cacctgttta tcatcttgtt taaatgtaaa     3720

tgtcccctta tgcttttgaa ataaatttcc ttttgtaatt ttgaaaaaaa aaaaaaa        3777


<210>  2596
<211>  1987
<212>  DNA
<213>  homo sapiens

<400>  2596
ggaggggaga gaaagagcga gagaagggga aagacaagtc gggagaggcc ggtaggcgtg       60

aggcgggcct gaagcggcag cgggcggcct tcgtccggcg agagctaggc cgaggacccg      120

cgccgcgctc cccggcacct caccgcgtcc ttcaccgact cccgcggcgc gcggccgggc      180

ggggaagggc gggcgggggt ctcctccagg ctgcgcgctc ggagccgcct gctgggcttg      240

ggcggggcgc ggggcccgcg gccgccctac ccggctcagt cctccccctg tgggacctgg      300

cgacggcggc ggagggagag gggagcggcg cccgggccgg ggccgggggc gggtggggag      360

gggggagggc ggcggccggg ctggggctcg ggatccgcat cgggatcggg ccgccatgga      420

cgacaaggcg ttcaccaagg agctggacca gtgggtcgag cagctgaacg agtgtaagca      480

gctgaacgag aaccaagtgc ggacgctgtg cgagaaggca aaggaaattt taacaaaaga      540

atcaaatgtg caagaggttc gttgccctgt tactgtctgt ggagatgtgc atggtcaatt      600

tcatgatctt atggaactct ttagaattgg tggaaaatca ccggatacaa actacttatt      660

catgggtgac tatgtagaca gaggatatta ttcagtggag actgtgactc ttcttgtagc      720

attaaaggtg cgttatccag aacgcattac aatattgaga ggaaatcacg aaagccgaca      780

aattacccaa gtatatggct tttatgatga atgtctgcga aagtatggga atgccaacgt      840

ttggaaatat tttacagatc tctttgatta tcttccactt acagctttag tagatggaca      900

gatattctgc ctccatggtg gcctctctcc atccatagac acactggatc atataagagc      960

cctggatcgt ttacaggaag ttccacatga gggcccaatg tgtgatctgt tatggtcaga     1020

tccagatgat cgtggtggat ggggtatttc accacgtggt gctggctaca catttggaca     1080

agacatttct gaaaccttta accatgccaa tggtctcaca ctggtttctc gtgcccacca     1140

gcttgtaatg gagggataca attggtgtca tgatcggaat gtggttacca ttttcagtgc     1200

acccaattac tgttatcgtt gtgggaacca ggctgctatc atggaattag atgacacttt     1260

aaaatattcc ttccttcaat ttgacccagc gcctcgtcgt ggtgagcctc atgttacacg     1320

gcgcacccca gactacttcc tataaatttc tcctgggaaa cctgcctttg tatgtggaag     1380

tatacctggc tttttaaaat atatgtattt aaaaacaaaa agcaacagta atctatgtgt     1440

ttctgtaaca aattgggatc tgtcttggca ttaaaccaca tcatggacca aatgtgccat     1500

actaatgatg agcatttagc acaatttgag actgaaattt agtacactat gttctaggtc     1560

agtctaacag tttgcctgct gtatttatag taaccatttt cctttggact gttcaagcaa     1620

aaaaggtaac taactgcttc atctcctttt gcgcttattt ggaaatttta gttatagtgt     1680

ttaactggca tggattaata gagttggagt tttattttta agaaaaattc acaagctaac     1740

ttccactaat ccattatcct ttattttatt gaaatgtata attaacttaa ctgaagaaaa     1800

ggttcttctt gggagtatgt tgtcataaca tttaaagaga tttcccttca tttaaactaa     1860

attactgttt tatgttgatc tgcatatttc tgtatatttg tcatgacagt gcttgcatcc     1920

tatttggtgt actcagcaaa taaacttttc attttaaaca aaaacattca aaaaaaaaaa     1980

aaaaaaa                                                               1987


<210>  2597
<211>  9433
<212>  DNA
<213>  homo sapiens

<400>  2597
cttatttctt atgaatgtcg gatagctgca ccagcttggt ggggaaaggg tttgatgaat       60

agcacaaaga cactggctgt tccctggagg ctgtcccttt aaaggagaat cttagtttat      120

tctgggggga ggggatgcac acattagagt aggaaagagg gcttggaata aaatgaaaac      180

actccccctt catagtcatt gtactgaaat gcaaagactg cttcctaagc tggagatgct      240

aaccttgggt agctccttct gttctcttca aggggaattt tgtcaggcta tggattcatt      300

tacaactgtt agtcatgtgg gcatgtgtga ggaaacagat gccagtttta atgtatttag      360

cccgaagttc caatttgata ggagccactg tcagtctctg aggttccacc aaaatatgga      420

acttgatttt ggacactttg acgaaagaga taagacatcc aggaacatgc gaggctcccg      480

gatgaatggg ttgcctagcc ccactcacag cgcccactgt agcttctacc gaaccagaac      540

cttgcaggca ctgagtaatg agaagaaagc caagaaggta cgtttctacc gcaatgggga      600

ccgctacttc aaggggattg tgtacgctgt gtcctctgac cgttttcgca gctttgacgc      660

cttgctggct gacctgacgc gatctctgtc tgacaacatc aacctgcctc agggagtgcg      720

ttacatttac accattgatg gatccaggaa gatcggaagc atggatgaac tggaggaagg      780

ggaaagctat gtctgttcct cagacaactt ctttaaaaag gtggagtaca ccaagaatgt      840

caatcccaac tggtctgtca acgtaaaaac atctgccaat atgaaagccc cccagtcctt      900

ggctagcagc aacagtgcac aggccaggga gaacaaggac tttgtgcgcc ccaagctggt      960

taccatcatc cgcagtgggg tgaagcctcg gaaggctgtg cgtgtgcttc tgaacaagaa     1020

gacagcccac tcttttgagc aagtcctcac tgatatcaca gaagccatca aactggagac     1080

cggggttgtc aaaaaactct acactctgga tggaaaacag gtaacttgtc tccatgattt     1140

ctttggtgat gatgatgtgt ttattgcctg tggtcctgaa aaatttcgct atgctcagga     1200

tgatttttct ctggatgaaa atgaatgccg agtcatgaag ggaaacccat cagccacagc     1260

tggcccaaag gcatccccaa cacctcagaa gacttcagcc aagagccctg gtcctatgcg     1320

ccgaagcaag tctccagctg actcagcaaa cggaacctcc agcagccagc tctctacccc     1380

caagtctaag cagtctccca tctctacgcc caccagtcct ggcagcctcc ggaagcacaa     1440

ggacctgtac ctgcctctgt ccttggatga ctcggactcg cttggtgatt ccatgtaaag     1500

gaggggagag tgctcagagt ccagagtaca aatccaagcc tatcattgta gtagggtact     1560

tctgctcaag tgtccaacag ggctattggt gctttcaagt ttttattttg ttgttgttgt     1620

tattttgaaa aacacattgt aatatgttgg gtttattttc ctgtgatttc tcctctgggc     1680

cactgatcca cagttaccaa ttatgagaga tagattgata accatccttt ggggcagcat     1740

tccagggatg caaaatgtgc tagtccatga cctttcaatg gaaagcttag gtgcctgcgt     1800

tatatttgcc ctgtctaatt ttgcccatac agtcttcctt ctgtagaggg ctgtttacat     1860

atacagcact taaaatgttt gtgtgggaaa aaaaaaactc attggcagat ccaagaatga     1920

caaacacaag tgcccctttt ctctggatct caagaatggt ggaggaccct ggaaggacag     1980

caaggcagct ccccagcctc actcttcact cctgattgag gcccgggttt gttgtccagc     2040

accaattctg gctgtcaatg gggagaaata aaccaacaac ttataattgt gacaccagat     2100

gcttaggatc ctggtgctgg gttagctaag agaatagaca gaattggaaa atactgcaga     2160

catttccgaa gagtttataa agcacagtga attcctggtc aatctctcca ctgaggcaat     2220

ttggaatcaa taagcaattg ataatagttt ggagtaaggg acttcatata cctgattcct     2280

ctagaaggct gtctaacata ccacatgatt acatgaactg tatggtatcc atctatctct     2340

gttctattga atgccttgtt aacagccaac actgaaaaca ctgtgagaat ttgttttcag     2400

gtctgacacc tttcagtctc tttttatagc aagaaatcaa tatccttttt ataaaaattc     2460

atgtctgtat ttcaggagca aactcttcag gctccttttt tataaactgg tgatttttct     2520

tttgtctaaa aaacacatga agaaaattta ccaaaaaaaa aaaaaaaagc agaagaataa     2580

tgtagtttag aaattatgct gtcactgcca aacagtaacc tccaggagaa aacaagatga     2640

atagcagagg ccaattcaat agaatcagtt ttttgatagc tttttaacag ttatgcttgc     2700

attaataatt tcaatgtgga ccagacattc taattatatt ttaaatgaaa tgttacagca     2760

tattttaagc aactcttttt atctataatc ctaatatttc atactgaaga cacagaaatc     2820

tttcacttgt ctttaacatt agaaaggatt tctctttact aaggactgat catttgaaat     2880

agttttcagt cttttgagat acaggtttat aacactgctt ttttttttct gtaatcatag     2940

cccataatgg caaagacaac taaatttaag tgaaggtcat gcatgccaat tctgtgtttg     3000

cttttagcag atatgaagat ttccttattt ctttgtaatt gtgcagatat tttgaaaggc     3060

acagcattcg aagccaagct gctgtttggc tactgaatgg cttgcagttg ttcctccact     3120

ctaaatggaa tgagcttgct gtgtgtgtgt gtggtggtgg tgggaggggg tggtgcatgt     3180

gtgtgtgtgt gtgtgcatct gcagctgctt caaaattagg aaatactaca ggacacccct     3240

gtaatggatt ggtggcaact gggtggcact gctgatgtgc actgtgtagg ggggaaccca     3300

gtggtggtgg ggtagctcag atgcccctag acaagcttca gatgtctgta gctaccagaa     3360

acattttcgg ttcaggaaaa gtgagatgat ggtagtactg gtttctggtg aaattgaaga     3420

accccaaatg atgaggatct ctttttgccc cctctccttt ttttgtagac ccattcaaaa     3480

ccattaataa gcccatttta ctaagcccct atttctttct agaagctcag ggttttctta     3540

gtgcctccca gaacattttg tagttaattg ggaaaaagtg atacttggat tagggggtgt     3600

gggcataaag aatggtggga ggcctgattt taaacttcag gccagaaccc ccaatgactc     3660

cacccatagt ctcactttag gtctcattta gtccatcacc tttattttaa gttgaggaag     3720

tggaggctgg taaagagcag gaccagagga agaatccaga tttccttatg cttgggcctc     3780

acactagctc tctgagtatt tccttgattg cggtatatgt actactagaa aataccaaat     3840

ggatatattt tctttaggat aacctttgaa ccaacaatct tcaataacaa tagtacatct     3900

tccatcttac ttttaatcga gtataaggaa atgtttcttt atggccattt tggagggagc     3960

aggggatgag gcttggcata gtccaaaatt taagtctcca ataattaatt gcattttaaa     4020

ttggcccact ttcaaggcaa ttttttttgt gtgtctgtaa ctgagctcct ccacccctgt     4080

cattcacttc caattttacc caatccaatt ttagcactca agttccattg tgttaatttc     4140

tgcacggtca acaaacatca agtcagcaag catttgccac cactccctat acttctccct     4200

ccttcttaca cacacacaca cacacacaca cacaatccat ctcttgcttg ttcctacctc     4260

ctgatttttc ttccctacag aaatagaaat agggacaaag aaggggaaaa tgtatatatt     4320

ggggctgggc tgaacaacta acttcataag tagtattaac taggggtaaa ttgagagaaa     4380

agctcctttt ctcttcactg ttttggaaag gatagccatt agcatgactg ctttgtgtcc     4440

ttatggactt tagtattagc ctagattgaa ttatagcgtt ttctagctgg aaggaacctt     4500

aagatcacat catctactcc tctactccaa atttctcatt cttcaggcca ggaaaccgag     4560

acacagaggt aaagtaattt ccccaaggtc acacagctgg ctggggcagg attgggttta     4620

caacccacat ctcctggctc ttattccagg gccttttccc actaagtagt attgccttcc     4680

attaggctcc tgagagttat ttctcagggt catgttgcat cttggagcca catgctgctg     4740

ccctgatctc agtgggaaat ccacccagca acctaataca gccccttttc cctgcattca     4800

cctggttccc atccacatgg gttgcagatg tccttgaaga gagtgaggca ttgagggcca     4860

ataggagcaa tggggtccct ggccttgtcc atctgattca ggagatcact gctccatcgt     4920

gaggagccct ctgaatagcc ccccactgaa tgcttgcctt gcccaaatgg aatggaggaa     4980

gattgatttt ctccatcagt tcaccttgtg tcatctcata atggttggtc tttccaggct     5040

gagggaaatg tttcttgttt ccagagtaga aaaagaaaga gtggaacaat agctttgttc     5100

atcctaactt tctgagatgg cttttcaaca ttttaaaaaa actagtgtgg ctaccattca     5160

ctggcaatga tttcttttag aatatgggag taagatgagc tagagaaaat aacctggtct     5220

cactgtggtt gccctcatcc acaatgtccc caaagccatc ctgctctgat gaggacaatt     5280

tccaggtata agcaaggggc tttgtgacaa aaatgtaccc tggctgatgt taaacattgg     5340

ctcctgtgtt tgcaccaaaa tagcaagctg tgtgctctat acactcttcc catcgtcttg     5400

tgtacactgc tcctgtggcc ttccacagca gaaaccaggg caaaagggtc caaacacatg     5460

gttttccttg ctgcaaggct cttcctggga actaaggggg tatttattag ttcagttcta     5520

agagacctcc ttctgggctt accccactcc tcaggtactt ctctctcctt cctccttctc     5580

ctccacagtc acaagtaacc aaggaacctg aaagtggatg tgtagctatt tgaagaaggc     5640

aaggaaccct gagattcttc tttgaatcct ctagtccaag tcttagacca gtgattggtg     5700

cttaccttga acaaaatttt gtctgtgttc ctaatccctt caatactctg ggtacaatgc     5760

tcccaatcac cctgcacatt tgattctaaa tggcttttat tttttaaaaa tccatatccc     5820

taggacaaga gaacaggatg cctatatccc caaaatgagc tccaggacac tgatgggaat     5880

gatcccaaag atcaccccac ctcagaaacg tctgtgccaa gagacttccc cagatagaaa     5940

cactgggaca gtggtttgaa cgacttcttt tatggttgtc cagtttgcta tggaaataaa     6000

aggcattgat tttttaaaaa gatgattgga acctgtcttt ggccacatag ggccacttgg     6060

atccatttcc aggccttact catatattgc cttcactgaa gggctttggc tttaagtccc     6120

agactggtct cccaagtgaa ccataagtgt tttggagctc atctggggtg aggcatgaga     6180

atgttgcccc atctatccct tcaggaaaag gtgccttccc tccctttctc ctaaagcctg     6240

gtccccagaa attgtttttg tctccaaaag tctagtatgg tctttataca cccagactct     6300

tagtgttgcg tcctgccttg tttccttgtt aaggatctat gcagacctcc cgctttggct     6360

tagctagcgt gacattggct atcatttgac aagactaact tttttttttt tttttttttg     6420

actgagtctc cctctgtcac ctaggctgga gtgcagtggc acaatcttgg ctcgctgcaa     6480

ccttcaccct tcacctccca ggtcgaagcg attctcctgc ctcagtctcc cgagtagctg     6540

ggattacagg cgtgcgccac caaatctggc tattttttta ttattattat ttttagtaga     6600

gatggggttt caccatgttg gccagactgg tcttgaactc ttggcctcaa attatctgcc     6660

cacctcggcc tcccaaagtg ctgggattac aggcatgagc caccatgccc agctgacaag     6720

actaattttt tatcccttgg tttattggct tcaacatctt ctggaatcag aggtgatttt     6780

ttcttacctt ggatgcctga gactagggga gtatagaatt ccaattggta attaaggcat     6840

ctttctgctc ctgatcagaa gggcaggtta gttgggagag gtcagatggc acaacagaag     6900

tcaccttgta agtaaggcaa agacttgaag gcattagcgt ttctcattac taggtcaata     6960

acctgaggga atcaatggct ttttgccgct ctacctcttg tgtatctctt tgacttttct     7020

ttctctgtct agtttcctct gttctcagtt tatattctat gttatcagtc tctctttcca     7080

cagtacaaac atccatcctt tctcctgtgc aattctgtct ctccctctta ttatctttat     7140

ttgtactttt tccttcctcc ctgtctaggc attgggcatg tgcctcttct tagcctgtga     7200

ttttgccttg ggactgatga taaattattt ccagattcaa tcagccctgg tcctacccca     7260

gtccaatcag aagtatgttg gtgggaatca acctgatcct ggccctttct tcttctccat     7320

tttcattcgt aatccccctc agcagatctt tacaagcagt ttccttatag ctcatgtatc     7380

tttaggtctt tgccttccaa gcactgtaca gaatactttg tggttccttt ttagtctgac     7440

attttgtgga gcagtgaagc gtgctcagag acataatcag ctgaagagaa aaaatccacc     7500

catggattta tatcagctaa atactaataa ttgattttgt ttgatgtgcc cataattttt     7560

aaagctgcaa tataatataa tgagggacca caggtaattt ctcctgtcat ttgttttggc     7620

tggatggggg tgggggagta attgcttaaa gttttaccat tacacattaa actctctata     7680

ataatcttgt ttggggcttg ctaactgttg agctgtttta actaaactgg taggcaatcg     7740

gagttgattt aaatgaaaag ataatttaac aaatctatac tataaaaaga gacatttgct     7800

taattgacat gtattttttc cttctgagtc acctaaacat ttactcttga caccaactgt     7860

tcatgatact gaatagacag tccatataag agaaattagt ggacctaaag aagccagatt     7920

gtaggtgtta atttattaaa cagagtgcaa agcccttgga aatgtcactg cttggcaata     7980

ccatatggaa tgccaaaatt tacaatgact tttctttata agttatccaa aagggatttg     8040

aacaagtaag aggttatgcc aaaatgtctc caatgtatgg tcctgtaata tattgcagct     8100

tgaagccaat gatcccttat gacttgtata caactaatgc atgttttatt gaattttgca     8160

tttcccacgt gtggtaagtt ctttaaaatg tttttgatca cctttttgtg ccattaaact     8220

tgtacagaaa atgtttttat ggccattttc aaagggagaa agtttaaaat ggaaacagcc     8280

caccctttct gccctatagc tgtagttaga attgagtacc tgtagcaaaa cagctgtaat     8340

tggtggttgt agtgttagag gtgttagctt gctagtgact agctttggag agtaaatgca     8400

tggtattgta catcacattt cttaactcgt tttaacctct gaaaagaata tattcttctt     8460

tgtagtcctt cttcccaccc ccttgccctc tccctctccc tgctcccagt tgtcttacag     8520

ttgtaaatat ctgatttgag gcccaataac tcttgccaag taaagtcagc aaacaacaaa     8580

caaaccaaaa tgtggggaaa aggcatttct caaccatctc tcagcagtta ttgatcattt     8640

cttaaggaac agcattgtga tcaaagactc aactttacgt aaaaatcagt ggtaaattgg     8700

ggttgtattt ggccatttga ttacatttca ggattgaata gttttcagaa tcacatgtaa     8760

tccaaagaca gtaggtagtg atgtccctta tccctgcagc tgttttaaga tagagacctc     8820

agaagactct gcttgaccga tgaccaataa ttatttgaaa aaaaaagaaa aaatgagaga     8880

aataaaacag atatttaaga actttagcca cctatttaga atagttatag ccagaaaaaa     8940

aaacaagggc atgagttcaa atgcattact atcagtgtcc taggcaatac ctaacctact     9000

ctgaaattgt gattcaaaag cagtatttca agaggcattc tccttttttg gtttgctgac     9060

cccacttgga ctggtaggtt tggtgaggcc cccataaacc agctggagca gacccttttc     9120

atctcctgtg cctgtaacac ccctcttccc ccaccccctc cgcaattcaa tgagggcttt     9180

cttgggtcag aggacttcaa ggttgtctag agaagtttgc catgtgtgta aggtgctgtg     9240

aactgtgagt gctgaagatt cgcagcattc aataccaggc agccaaagag ctgctcttgc     9300

aattattttg gctctcaagc tctgttcttc atcgcattct catttctgtg tacatttgca     9360

agatgtgtgt aatgtcattt tccaaaaata aaatttgatt tcaataaaaa aaaaaaaaaa     9420

aaaaaaaaaa aaa                                                        9433


<210>  2598
<211>  907
<212>  DNA
<213>  homo sapiens

<400>  2598
cttttcttaa gggaaaaatc actctgtgtt cttttaaaat ccctcaggtt ttatgtttta       60

ttgctaccag agtctgcctc cctgaggttc ttgtatagac tagttatttc cctctgtaaa      120

gaagctgttc tattcgttct cgcctggttt ggaacaaact gaacacttcc aaaggaggca      180

gtccttgcag ccttgtctcc ttccactccc ctcctcccca cagtcctggc tggagcagcg      240

agtctgtcga tcccaggcca gagacaaggc agacaaaggt tcatttgtaa agaagctcct      300

tccagcacct cctctcttct ccttttgccc aaactcaccc agtgagtgtg agcatttaag      360

aagcatcctc tgccaagacc aaaaggaaag aagaaaaagg gccaaaagcc aaaatgaaac      420

tgatggtact tgttttcacc attgggctaa ctttgctgct aggagttcaa gccatgcctg      480

caaatcgcct ctcttgctac agaaagatac taaaagatca caactgtcac aaccttccgg      540

aaggagtagc tgacctgaca cagattgatg tcaatgtcca ggatcatttc tgggatggga      600

agggatgtga gatgatctgt tactgcaact tcagcgaatt gctctgctgc ccaaaagacg      660

ttttctttgg accaaagatc tctttcgtga ttccttgcaa caatcaatga gaatcttcat      720

gtattctgga gaacaccatt cctgatttcc cacaaactgc actacatcag tataactgca      780

tttctagttt ctatatagtg caatagagca tagattctat aaattcttac ttgtctaaga      840

caagtaaatc tgtgttaaac aagtagtaat aaaagttaat tcaatctaat ttttctctgt      900

ggaaaaa                                                                907


<210>  2599
<211>  2018
<212>  DNA
<213>  homo sapiens

<400>  2599
tgcgtgccgc cgttgatccg gtgctgcagt gaggaggtgg ttcttgcccg tgttgtgtgt       60

gtgtgtgagt gagagagcga gtgagtgagt gagtgagtgt gtgtgtgggg gggactcggc      120

ttgttgttgt cggtgacttc cccctcccct tcaccccttc ccctccccgc cgccgctgca      180

gtggccgctc cctgggccgt aggaaatgag cgataacgat gacatcgagg tggagagcga      240

cgctgacaaa cgggctcatc ataatgcact ggaacgaaaa cgtagggacc acatcaaaga      300

cagctttcac agtttgcggg actcagtccc atcactccaa ggagagaagg catcccgggc      360

ccaaatccta gacaaagcca cagaatatat ccagtatatg cgaaggaaaa accacacaca      420

ccagcaagat attgacgacc tcaagcggca gaatgctctt ctggagcagc aagtccgtgc      480

actggagaag gcgaggtcaa gtgcccaact gcagaccaac tacccctcct cagacaacag      540

cctctacacc aacgccaagg gcagcaccat ctctgccttc gatgggggct cggactccag      600

ctcggagtct gagcctgaag agccccaaag caggaagaag ctccggatgg aggccagcta      660

agccactcgg ggcaggccag caataaaaac tgtctgtctc catcgtctca tcctcctttc      720

agttcgttgg tagagccctc agaaccattt aagagactct ttatttttct ctttctccct      780

ttttttttta aatttttatt tttacgtaga agctcttgga caacagctct cgttctcctt      840

ccccatttcc actgtatatt ttttaatgta ttcccttcag ggattccctg tccccaacag      900

gaatttttaa accaaaacac cccaacttgg cagctttttc tgtggaggac agacggccgg      960

ccggacctct gagcacatag tgtcctgccc accctaccag ctcctccagc cctgccgggc     1020

acatgcccgg gggacgcctg ccctgcccag gtggcctcct ggcccgccct cacctctgat     1080

agactttgtg aatctgaact gctctacttt gagaagatga ccggtttgga gtaatcagaa     1140

tgaaccctcc tcctttttaa gggttttttt tttttccttt ttctaaaaag ctatgtatcg     1200

ctcctattga aagaccagat ccttagagaa gtttgtggta taaaaaggaa gtggggacag     1260

attcgcagca cagagtcgct ggcatgtttc actcctgctt ctctcagcca gctgtttaag     1320

cctgcggcgc cagcctcacg gagggccgtg tgacactctc gtggtatgta tgggagatgg     1380

cagcagtgaa gcagcagcca ccagggagtg gccatttggg gttgggacag ggagggtgtt     1440

ttgggtggca tagaggtttt gtattgaggg ccagtgatga tgttttgata tttatttcct     1500

gctacttaaa tttgaatctg agtgaattgt acctatttct gatgatgtcg gtcttgcaaa     1560

gcgacagatt cataaagtaa tgatgaaatc tttctttctt cccgtgtgta tttctaagaa     1620

atagagccaa ctgattttgt atgtaaatac caagagcaat ttacctggta ctaaacccgc     1680

accccagtgc ggacccttcc cagccctcat cccacttcct ttcctactgt cctggaacct     1740

gtctccattg tgtgatccag ccctggttct ggctgtggtc agcagatgcc agtgaagggt     1800

tttgtgtgtt taggcctcat ttctttgtct ttttcctact ccgttcctgg catttgctga     1860

tttctagtgt atactctgta gtctcagttc gtgtttgatt ccattccatg gaaataaaaa     1920

gtatgttgta catactgccg aagaattgtc ttgcaagtta aggcttcccc ctttactata     1980

agactataaa taaaaactta ttttatcctt cttaaaaa                             2018


<210>  2600
<211>  1366
<212>  DNA
<213>  homo sapiens

<400>  2600
gggaaagtgt gagaggaaga gttggagaaa agtcggggga aagtagggac agggttaagg       60

ggagagagga ggatgagggc ggcgaggaga gattaaaagg ggaagggggg tcgctggaga      120

ggagggcgga ctgtggatcg gaggtattgc gcagcgatgc acggccatca agtaccactt      180

ttctcagccc atccgcttgc gaaacattcc ttttaattta accaagacca tacagcaaga      240

tgagtggcac ctgcttcatt taagaagaat cactgctggc ttcctcggca tggccgtagc      300

cgtccttctc tgcggctgca ttgtggccac agtcagtttc ttctgggagg agagcttgac      360

ccagcacgtg gctggactcc tgttcctcat gacagggata ttttgcacca tttccctctg      420

tacttatgcc gccagtatct cgtatgattt gaaccggctc ccaaagctaa tttatagcct      480

gcctgctgat gtggaacatg gttacagctg gtccatcttt tgcgcctggt gcagtttagg      540

ctttattgtg gcagctggag gtctctgcat cgcttatccg tttattagcc ggaccaagat      600

tgcacagcta aagtctggca gagactccac ggtatgactg tcctcactgg gcctgtccac      660

agtgcgagcg actcctgagg ggaacagcgc ggagttcagg agtccaagca caaagcggtc      720

ttttacattc caacctgttg cctgccagcc ctttctggat tactgataga aaatcatgca      780

aaacctccca acctttctaa ggacaagact actgtggatt caagtgcttt aatgactatt      840

tatgcgttga ctgtgagaat agggagcagt gccatgggac atttctaggt gtagagaaag      900

aagaaactgc aatggaaaaa tttgtatgat ttccatttat ttcagaaagt ttgtatgtaa      960

caattacccg agagtcattt ctacttgcaa aaggattcgt aacaaagcga gtataatttt     1020

cttgtcattg tatcatgctt gttaaatttt aatgcagcat cttcagaact tgtcctgatg     1080

gtgtcttatt gtgtcagcac caaatatttg tgcattattt gtggacgttc cttgtcacag     1140

gaagattctt cttctgttgc cttattgttt tttttttttt aagtctcttc tctgtctttg     1200

tactggaatc gaaatcataa gataaacaga tcaaacgtgc ttaagagcta actcgtgaca     1260

ctatgcagta ttgtttgaag acctgttgtt caacctctgt ctctttatgt taactggatt     1320

tctgcattaa atgactgccc ccttgttaaa aaaaaaaaaa aaaaaa                    1366


<210>  2601
<211>  4060
<212>  DNA
<213>  homo sapiens

<400>  2601
acccaccccg tgagcagccc aaaccgacca ccgtcctccc ccagctccca ccaatcggat       60

cgcagggact cgagccccac actgctgagt ccgctgacac tgcgtccggg gccagacgac      120

gatatcagcg cggggtcccc acaacgccat ggggcagagc caactctcga gcgcgtgatc      180

gaagcccgca gttttttcgc ccccgtcact tccgggtgcg acaatctctt ctgtccggcc      240

agccgctgga gtcgttaggt gccgccttgc ttctgacgag ccacacgttt gcttcttccc      300

tgtgttccca gctggaggga catgagtgtc cctgggccgt cgtctccgga cggggccctg      360

acacggccac cctactgcct ggaggccggg gagccgacgc ctggtttaag tgacacttct      420

ccagatgaag ggttaataga ggacttgact atagaagaca aagcagtgga gcaactggca      480

gaaggattgc tttctcatta tttgccagat ctgcagagat caaaacaagc cctccaggaa      540

ctcacacaga accaagttgt attgttagac acactggaac aagagatttc aaaatttaaa      600

gaatgtcatt ctatgttgga tattaatgct ttgtttgctg aggctaaaca ctatcatgcc      660

aagttggtga atataagaaa agagatgctg atgcttcatg aaaaaacatc aaagttaaaa      720

aaaagagcac ttaaactgca gcagaagagg caaaaagaag agttggaaag ggagcagcaa      780

cgagagaagg agtttgaaag agaaaagcag ttaactgcca gaccagccaa aaggatgtga      840

aaagttgtgt ttgtgtgttt tcttctcctg tcccatattt gggttatgat gactcaagtg      900

tagactgaag ttgaggtagt gccttatgcc attatgtcat atgttgaaat ccttattccg      960

gtattactgt gtctccatgc cttttttcca agtagcagac gtcatgttgc atggtttttg     1020

atatttatat gtaagttttt caaattttgc ttaattttaa aatttattat tttgatcttg     1080

aattatttat aaactggaaa gtggtttgat tattgtgagt caaaactcta agtggttaaa     1140

aattagtatg aattttttag cttcttaatg aatatggatt taaaactctc cagttcttat     1200

tttatgaaat gacttgcctt tctggtaata caatgctgat tttttagtaa ttgccttttc     1260

attactttgt taagaagaaa tgccagctgt ttaatcacac ctacccctgg aaaagaggta     1320

aaccttttga acagttgaat ttcatcagaa gctctatagc tttttggtga gaggaagtga     1380

tactctttat tacaagaaac aaggaattaa caaaaataag gaacttgttg ctacctttct     1440

tttctgttga acattaaaaa taatttggtt tgtggactgg gcatggtggc ttatggaaaa     1500

gaggtgagcc tttgtgaaga acataatgga aaagtgcatg tacgggaaat aacagcactt     1560

taggtgtagt tcaggtgagc aagatgccag atagtttcta ctaaccatat actctttctg     1620

cttcttagcg tcgttgtcac tgcttctgtg gcttttgggt tcaaagtaga ttatatatat     1680

tcctaaagct tggtggaggt agtggagcta tcacacactc aaatgagctt gtatatttat     1740

aatacaatat agtattatag taacagttat catacactga gatatagttt ctgtgcttgt     1800

aaaaaattct tgaagtgagg ccgggtgcgg tggctcatgc ctgtaatccc aacgctttgg     1860

gacgccgagg cgggtggatc atgaggtcaa aagattgaga ccatcctggc caacatggtg     1920

aaaccccgtc tctactagaa atacaaaaat tagctgggtg tgggggcgtg cgcctgtagt     1980

cccagctact tgggaggctg aggcaggaga attgcttgaa cccaggaggc agaggttgca     2040

gtaagccaag atcgtgccac tgcactccag ccttggtgac agagcaagac tccgtctcca     2100

aaaaaaagaa aaaaaaattt cttgaagtgg aatgatgtac accaaatacc cactttatag     2160

ataattacag ggatggtgaa aaattagtaa atagcttcac aaaagaggca gcgtgatacc     2220

tttagtgttt tctagaattt ttttctggat attatatgta agaatttatt gtttgaggga     2280

aatacgaggt ttcattgttt aaaatcaaga gtgtattgtt tactgtttta cagtattatt     2340

taatatccaa ctggtctcca atctccatta catagggact gtacagagcc tgtgaagatg     2400

tatgaatggt atcttttata atccacaata catttctggt aagatggaat cactacctct     2460

gatcacatat caggctaacg atagagaaag cattaggttt aagttgaggg ctaagaactg     2520

gtttgtttaa aggtttaaat tgttggaaaa gagcatttgc cttctttaat gaatgatggt     2580

ctcacaattc agttgacttt gacctaatat ttaagaatat aaatatattt tatttgaaag     2640

gctgagtgtt gccctcaaac acttgctaaa actgcctagg gcaggattca ttagggcttg     2700

cagacaatgt cacctaaatt gctgaatgta ctcattataa tatgatatct gacaaaggta     2760

gtacagcgtt tctgagtcat ttgggaccaa ctgcagtggt tgtttaaaat gctggttcct     2820

gcacacaatt ctctatctac tgaagcacat ctgttttctt tgtttgtttt gctttgcttt     2880

ttgtttttaa agtttccccc agtgattcca gtgcacctga aaagttgaga accacaggct     2940

tagtggtacg ttggggtttc ccacgctagg ctgcatagca ttataacctg ggaacgttaa     3000

aaaaaataca gacattcttg attcttagtg tagttatgat gtggatccta cgtatttttt     3060

aaaaaactct ccagataatt ttgatgtcac gagtcactag tatagactat ctatctagtg     3120

agttgtatta taagcgatga aatactttaa aagctaccca gtaactcttg ggattaattt     3180

tatgaaataa attctgagct gctgcttttg atatagtcag acttaagact gaaccccagt     3240

agacaggcaa tagatataga attctggtta gctaattgaa cttttgtgac ctgtttaaaa     3300

acaaatcaaa tttattgaac aaatgacaag gcacaaatac tttcagaatt gtatttcagt     3360

tttgaagatt taaaaaaaat gtgaaaataa atatatatta gtatccttta ttttaaagtc     3420

aattgtaaac cagaagtact gttattttgg tgattaaaat ccaaaacttt agctgtattt     3480

cagtaacaaa aacatacctt actagactgt gatggctcac acctgtaatc ccagtgcttt     3540

gggaggctga ggtgggaaga ttctttgagc ccaggagttc aaggctgcag tgaattctga     3600

tcgcaccact gaactccagc ccgtatgaca gagtgagacc ctgtttctaa aaacaaaaca     3660

aacaaacaaa caaacaacgt atcttactga ctaaactgga atggaaatct tataattagt     3720

gttgtatttt tctgcaaaat agtgaattgg tacttgggag acttctgttc tttgttgaaa     3780

aaaattgcct ttgttttgaa attatatcac ctgtgttctg aactaaaatg atgggagttc     3840

attttgtatt tactttgcag taagtatcat gtaaatatgc aaatgttgaa tgtaatatag     3900

attgtgtcct cattgagttt ttgggtgata cagtttataa atataacaat tatacaccct     3960

catacattcg tctgattttg agcttgtaag atgagaactg ctttttacac atttaataaa     4020

aaaaggtctc tgaattatct gaaaaaaaaa aaaaaaaaaa                           4060


<210>  2602
<211>  1687
<212>  DNA
<213>  homo sapiens

<400>  2602
gattgtggga aggcagctga actcggcgcc tggaaagatg gaggcagcgg agacagaggc       60

ggaagctgca gccctagagg tcctggctga ggtggcaggc atcttggaac ctgtaggcct      120

gcaggaggag gcagaactgc cagccaagat cctggttgag tttgtggtgg actctcagaa      180

gaaagacaag ctgctctgca gccagcttca ggtagcggat ttcctgcaga acatcctggc      240

tcaggaggac actgctaagg gtctcgaccc cttggcttct gaagacacga gccgacagaa      300

ggcaattgca gctaaggaac aatggaaaga gctgaaggcc acctacaggg agcacgtaga      360

ggccatcaaa attggcctca ccaaggccct gactcagatg gaggaagccc agaggaaacg      420

gacacaactc cgggaagcct ttgagcagct ccaggccaag aaacaaatgg ccatggagaa      480

acgcagagca gtccagaacc agtggcagct acaacaggag aagcatctgc agcatctggc      540

ggaggtttct gcagaggtga gggagcgtaa gacagggact cagcaggagc ttgacagggt      600

gtttcagaaa cttggaaacc tgaagcagca ggcagaacag gagcgggaca agctgcagag      660

gtatcagacc ttcctccagc ttctgtatac cctgcagggt aagctgttgt tccctgaggc      720

tgaggctgag gcagagaatc ttccagatga taaaccccag cagccgactc gaccccagga      780

gcagagtaca ggagacacca tggggagaga ccctggtgtg tccttcaagg ctgttggtct      840

acaacctgct ggagatgtaa atttgccatg acttcctgga ggacagcagc atggagaaag      900

atcctagaaa aggcctctga cttccctcac ctcccaacca tcattacagg aaagactgtg      960

aactcctgag ttcagcttga tttctgacta catcccagca agctctggca tctgtggatt     1020

aaaatccctg gatctctctc agttgtgtat ttgttcatct tcatatgctg gcaggaacaa     1080

ctattaatac agatactcag aagccaataa catgacagga gctgggactg gtttgaacac     1140

agggtgtgca gatggggagg gggtactggc cttgggcctc ctatgatgca gacatggtga     1200

atttaattca aggaggagga gaatgtttta ggcaggtggt tatatgtggg aagataattt     1260

tattcatgga tccaaatgtt tgttgagtcc tttctttgtg ctaaggttct tgcggtgaac     1320

cagaattata acagtgagct catctgactg ttttaggatg tacagcctag tgttaacatt     1380

cttggtatct ttttgtgcct tatctaaaac atttctcgat cactggtttc agatgttcat     1440

ttattatatt cttttcaaag attcagagat tggcttttgt catccactat tgtatgtttt     1500

gtttcattga cctctagtga taccttgatc tttcccactt tctgttttcg gattggagaa     1560

gatgtacctt ttttgtcaac tcttactttt atcagatgat caactcacgt atttggatct     1620

ttatttgttt tctcaaataa atatttaagg ttatacattt aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaa                                                               1687


<210>  2603
<211>  6723
<212>  DNA
<213>  homo sapiens

<400>  2603
atggaactat ctcctgagtg ctgcaagttg taacgggcac cgctgagcct gtttcccttt       60

ggagcacttc ttatctagaa gcagtgttta gtttcttcca aactgggcca cttcgtccac      120

ctactctgtt ctgagtaagg aaacagcctc caagcatcag cagagcccag atgagcacgg      180

gccgcggagc cgcttagcag tctcccggga cccagctccg gaggagccgc aagcatgcac      240

cctgggttgt ggctgctcct ggttacgttg tgcctgaccg aggaactggc agcagcggga      300

gagaagtctt atggaaagcc atgtgggggc caggactgca gtgggagctg tcagtgtttt      360

cctgagaaag gagcgagagg acgacctgga ccaattggaa ttcaaggccc aacaggtcct      420

caaggattca ctggctctac tggtttatcg ggattgaaag gagaaagggg tttcccaggc      480

cttctgggac cttatggacc aaaaggagat aagggtccca tgggagttcc tggctttctt      540

ggcatcaatg ggattccggg ccaccctgga caaccaggcc ccagaggccc acctggtctg      600

gatggctgta atggaactca aggagctgtt ggatttccag gccctgatgg ctatcctggg      660

cttctcggac cacccgggct tcctggtcag aaaggatcaa aaggtgaccc tgtccttgct      720

ccaggtagtt tcaaaggaat gaagggggat cctgggctgc ctggactgga tggaatcact      780

ggcccacaag gagcacccgg atttcctgga gctgtaggac ctgcaggacc accaggatta      840

caaggtcctc cagggcctcc tggtcctctt ggtcctgatg ggaatatggg gctaggtttt      900

caaggagaga aaggagtcaa gggggatgtt ggcctccctg gcccagcagg acctccacca      960

tctactggag agctggaatt catgggattc cccaaaggga agaaaggatc caagggtgaa     1020

ccagggccta agggttttcc aggcataagt ggccctccag gcttcccggg ccttggaact     1080

actggagaaa agggagaaaa gggagaaaag ggaatccctg gtttgccagg acctaggggt     1140

cccatgggtt cagaaggagt ccaaggccct ccagggcaac agggcaagaa agggaccctg     1200

ggatttcctg ggcttaatgg attccaagga attgagggtc aaaagggtga cattggcctg     1260

ccaggcccag atgttttcat cgatatagat ggtgctgtga tctcaggtaa tcctggagat     1320

cctggtgtac ctggcctccc aggccttaaa ggagatgaag gcatccaagg cctacgtggc     1380

ccttctggtg tccctggatt gccagcatta tcaggtgtcc caggagccct agggcctcag     1440

ggatttccag ggctgaaggg ggaccaagga aacccaggcc gtaccacaat tggagcagct     1500

ggcctccctg gcagagatgg tttgccaggc ccaccaggtc caccaggccc acctagtcca     1560

gaatttgaga ctgaaactct acacaacaaa gagtcagggt tccctggtct ccgaggagaa     1620

caaggtccaa aaggaaacct aggcctcaaa ggaataaaag gagactcagg tttctgtgct     1680

tgtgacggtg gtgttcccaa cactggacca cccggggaac caggcccacc tggtccatgg     1740

ggtctcatag gccttccagg ccttaaagga gccagaggag atcgaggctc tgggggtgca     1800

cagggcccag caggggctcc aggcttagtt gggcctctgg gtccttcagg acccaaagga     1860

aagaaggggg aaccaattct cagtacaatc caaggaatgc caggagatcg gggtgattct     1920

ggctcccagg gcttccgtgg tgtaatagga gaaccaggca aggacggagt accaggttta     1980

ccaggtctgc caggccttcc gggtgatggt ggacagggct tcccaggtga aaaggggtta     2040

cctggacttc ctggtgaaaa aggccatcct ggtccacctg gcctcccagg aaatgggtta     2100

ccaggacttc ctggaccccg tgggcttcct ggagataaag gcaaggatgg attaccggga     2160

caacaaggcc ttcccggatc taagggaatc accctgccct gtattattcc tgggtcatac     2220

ggtccatcag gatttccagg cactcccgga ttcccaggcc ctaaagggtc tcgaggcctc     2280

cctgggaccc caggccagcc tgggtcaagt ggaagtaaag gagagccagg gagtccagga     2340

ttggttcatc ttcctgaatt accaggattt cctggacctc gtggggagaa gggcttgcct     2400

gggtttcctg ggctccctgg aaaagatggc ttgcctggga tgattggcag tccaggctta     2460

cctggttcca agggagccac tggtgacatc tttggtgctg aaaatggtgc tccgggggaa     2520

caaggcctac aaggattaac agggcacaaa ggatttcttg gagactctgg ccttccagga     2580

ctcaagggtg tgcacgggaa gcctggctta ctaggcccca aaggtgagcg gggcagccct     2640

gggacaccag gacaggtggg acagccaggc accccaggat ctagtggtcc atatggcatc     2700

aagggcaaat ctgggctccc aggagcacca ggcttcccag gcatctcagg acatcctgga     2760

aagaaaggaa caagaggcaa gaaaggtcct cctggatcaa ttgtaaagaa agggctgcca     2820

gggctaaaag gccttcctgg aaatccaggc ctagtaggac tgaaaggaag cccaggctct     2880

ccaggggtcg ctgggttgcc agccctctct ggacccaagg gagagaaggg gtctgttgga     2940

ttcgtaggtt ttccaggaat accaggtctg cctggtattc ctggaacaag aggattaaaa     3000

ggaattccag gatcaactgg aaaaatggga ccatctggac gtgctggtac tcctggtgaa     3060

aagggagaca gaggcaatcc ggggccagtc ggaataccta gtccaagacg tccaatgtca     3120

aacctttggc tcaaaggaga caaaggctct caaggctcag ccggatccaa tggatttcct     3180

gggccaagag gtgacaaagg agaggctggt cgacctggac caccaggcct acctggagct     3240

cctggcctcc caggcattat caaaggagtt agtggaaagc cagggccccc tggcttcatg     3300

ggaatccggg gcttacctgg cctgaagggg tcctctggga tcacaggttt cccaggaatg     3360

ccaggagaaa gtggttcaca aggtatcaga gggtcgcctg gactcccagg agcatctggt     3420

ctcccaggcc tgaaaggaga caacggccag acagttgaaa tttccggtag cccaggaccc     3480

aagggacagc ctggcgaatc tggttttaaa ggcacaaaag gaagagatgg actaataggc     3540

aatataggct tccctggaaa caaaggtgaa gatggaaaag ttggtgtttc tggagatgtt     3600

ggccttcctg gagctccagg atttccagga gttgccggca tgagaggaga accaggactt     3660

ccaggttctt ctggtcacca aggggcaatt gggcctctag gatcccccgg attaatagga     3720

cccaaaggct tccctggatt tcctggttta catggactga atgggcttcc gggcaccaag     3780

ggtacccatg gcactccagg acctagtatc accggtgtgc ctgggcctgc tggtctccct     3840

ggacccaaag gagaaaaagg atatccagga attggcatcg gagctccagg gaagccgggc     3900

ctgagagggc aaaaaggtga tcgaggtttc ccaggtctcc agggccctgc tggtctcccc     3960

ggtgccccag gcatctcctt gccctcactc atagcaggac agcctggtga ccccgggcga     4020

ccaggcctag atggagaacg aggccgccca ggccccgctg gacccccagg tccccctggg     4080

ccatcctcga atcaaggcga caccggagac cctggcttcc ctggaattcc tggacctaaa     4140

gggcctaagg gagaccaagg aattccaggt ttttctggcc tccctggaga gctaggactg     4200

aaaggcatga gaggtgagcc tggcttcatg gggactccag gcaaggttgg gccacctgga     4260

gacccaggat ttcccggaat gaaggggaag gcagggccaa gaggctcttc tggcctccaa     4320

ggtgatcctg gacaaacacc aactgcagaa gctgtccagg ttcctcctgg acccttgggt     4380

ctaccaggga tcgatggcat ccctggcctc actggggacc ctggggctca aggccctgta     4440

ggcctacaag gctccaaagg tttacctggc atccccggta aagatggccc cagtgggctc     4500

ccaggcccac ctggggctct tggtgatcct ggtctgcctg gactgcaagg ccctccagga     4560

tttgaaggag ctccagggca gcaaggcccc ttcgggatgc ctggaatgcc tggccagagc     4620

atgagagtgg gctacacgtt ggtaaagcac agccagtcgg aacaggtgcc cccgtgtccc     4680

atcgggatga gccagctgtg ggtggggtac agcttactgt ttgtggaggg gcaagagaaa     4740

gcccacaacc aggacctggg ctttgctggc tcctgtctgc cccgcttcag caccatgccc     4800

ttcatctact gcaacatcaa cgaggtgtgc cactatgcca ggcgcaatga taaatcttac     4860

tggctctcca ctaccgcccc tatccccatg atgcccgtca gccagaccca gattccccag     4920

tacatcagcc gctgctctgt gtgtgaggca ccctcgcaag ccattgctgt gcacagccag     4980

gacatcacca tcccgcagtg ccccctgggc tggcgcagcc tctggattgg gtactctttc     5040

ctcatgcaca ctgccgctgg tgccgagggt ggaggccagt ccctggtctc acctggctcc     5100

tgcctagagg actttcgggc cactcctttc atcgaatgca gtggtgcccg aggcacctgc     5160

cactactttg caaacaagta cagtttctgg ttgaccacag tggaggagag gcagcagttt     5220

ggggagttgc ctgtgtctga aacgctgaaa gctgggcagc tccacactcg agtcagtcgc     5280

tgccaggtgt gtatgaaaag cctgtagggt ggcacctgcc actctgcccc ttgccctccc     5340

ctgcccctca caacagtcac ctcacaaacc tgaatggtct gaagaaggaa ggcctgagcc     5400

cctttgcctg tcaagttgta cattggagtc tcatttgggc tagactaccg gacactcgtc     5460

accccagccc tcgggtccat agagatgagc ccaccctgct gagatctgct gtcctgtttc     5520

tgtcaagctg gtgctactgt ttgatttgga tgattgtgtg actattcatg gctacctcag     5580

aaagatttga tgggccacaa ctgtcttaga ctgctagctt tctccttacc gtcttgatcg     5640

gaaagctctt cctaatcgct aatcagtcat ttcttcatgt acagaggtca gcacacatta     5700

tttggcttaa accagaaccc agtgtttcca cacttaaatt ctctaaccga atattcatgg     5760

atggctcaag tctgcacaga gcaagtcctc actcttcaag gaggcccact gtgtctaggc     5820

aggcaagaga attgaaatga ggtgccaccc agtagcccag agtgagcttt agctctctct     5880

agaatgagca agactgggcc ccacatggct tagagaggct tgaaggccag cagctgggtt     5940

gggggtggtg gtcattaatg gcatatggtc ctagacaaac catctcctcc ttgccggctc     6000

cccctccagc cagagacaga ggatgtggcc tggttcaaag taaagcagag gatgcaacaa     6060

atgtggccaa gcctatcaaa ggaaatgaga atgacagcct tttttcctgg gccagaagta     6120

gaggggtggg tgcgtaagga tgtgtgagtt ttgcttttga ctccaggaac aaaaaggtaa     6180

atcccacatc ccagtttctc agaagtccct gtttattcca aatgccatcc agatgtgtgc     6240

aatgtggcaa actgaagctg cacagtgttg gtttccttgt attctgagga tgttaaagac     6300

tttgttaaat ggttatccaa ttgctctttc acaggtagcc tattaaacta ttttaatatg     6360

tttttttaaa cctcataaaa atctagcaca ctcttctctt gagcagttag cagacctaaa     6420

gcaagcctga attggctatg cagtacattg tattctgttt gggggaattt gttttagcca     6480

ttttctttaa ttaccagttt tccagaacac tcttagctat gttgacatga ggcagttcct     6540

tccaggtgat tctgtttcct taagtattat ataaactgtg ccaatacaga caaagcataa     6600

tcaatataat ctgaattatt gttatcttta cctcctgagt aataagcatg gtgtcagttt     6660

tgtacatagc aaataaaata aatgaaatct gaacatgtga aaaaaaaaaa aaaaaaaaaa     6720

aaa                                                                   6723


<210>  2604
<211>  10669
<212>  DNA
<213>  homo sapiens

<400>  2604
tgtggctcgg gcggcggcgg cgcggcggcg gcagaggggg ctccggggtc ggaccatccg       60

ctctccctgc gctctccgca ccgcggctta aatgatgtat tttgtgatcg cagcgatgaa      120

agctcaaatt gaaattattc catgcaagat ctgtggagac aaatcatcag gaatccatta      180

tggtgtcatt acatgtgaag gctgcaaggg ctttttcagg agaagtcagc aaagcaatgc      240

cacctactcc tgtcctcgtc agaagaactg tttgattgat cgaaccagta gaaaccgctg      300

ccaacactgt cgattacaga aatgccttgc cgtagggatg tctcgagatg ctgtaaaatt      360

tggccgaatg tcaaaaaagc agagagacag cttgtatgca gaagtacaga aacaccggat      420

gcagcagcag cagcgcgacc accagcagca gcctggagag gctgagccgc tgacgcccac      480

ctacaacatc tcggccaacg ggctgacgga acttcacgac gacctcagta actacattga      540

cgggcacacc cctgagggga gtaaggcaga ctccgccgtc agcagcttct acctggacat      600

acagccttcc ccagaccagt caggtcttga tatcaatgga atcaaaccag aaccaatatg      660

tgactacaca ccagcatcag gcttctttcc ctactgttcg ttcaccaacg gcgagacttc      720

cccaactgtg tccatggcag aattagaaca ccttgcacag aatatatcta aatcgcatct      780

ggaaacctgc caatacttga gagaagagct ccagcagata acgtggcaga cctttttaca      840

ggaagaaatt gagaactatc aaaacaagca gcgggaggtg atgtggcaat tgtgtgccat      900

caaaattaca gaagctatac agtatgtggt ggagtttgcc aaacgcattg atggatttat      960

ggaactgtgt caaaatgatc aaattgtgct tctaaaagca ggttctctag aggtggtgtt     1020

tatcagaatg tgccgtgcct ttgactctca gaacaacacc gtgtactttg atgggaagta     1080

tgccagcccc gacgtcttca aatccttagg ttgtgaagac tttattagct ttgtgtttga     1140

atttggaaag agtttatgtt ctatgcacct gactgaagat gaaattgcat tattttctgc     1200

atttgtactg atgtcagcag atcgctcatg gctgcaagaa aaggtaaaaa ttgaaaaact     1260

gcaacagaaa attcagctag ctcttcaaca cgtcctacag aagaatcacc gagaagatgg     1320

aatactaaca aagttaatat gcaaggtgtc tacattaaga gccttatgtg gacgacatac     1380

agaaaagcta atggcattta aagcaatata cccagacatt gtgcgacttc attttcctcc     1440

attatacaag gagttgttca cttcagaatt tgagccagca atgcaaattg atgggtaaat     1500

gttatcacct aagcacttct agaatgtctg aagtacaaac atgaaaaaca aacaaaaaaa     1560

ttaaccgaga cactttatat ggccctgcac agacctggag cgccacacac tgcacatctt     1620

ttggtgatcg gggtcaggca aaggagggga aacaatgaaa acaaataaaa gttgaacttg     1680

tttttctcat gcatatgatt tccattatgc ctacagatat ggaccctttt tctgtcttga     1740

cttcttgatc attgacctct gtttacaaca ggaggagggt actaaagtcg gaggatttcc     1800

ttttcttgta gctcactgcc cacagacttt ctacagagtc accaatctgt cagtaacaac     1860

agagagtcca gcaataatcg gtgactggtg tgcatagcgg aggttgcggc attactttgc     1920

acaactagct ctttgtttca tgaaggaagt ttttattttt tcaccgatta ttgccagtcc     1980

gcaggatggc atgaaaaggg tccatagcag tagcaacaat agcattataa tatattacag     2040

ggtaaatggg catgaagact atatatagct aaaagagata ttgtttatat attgttttaa     2100

gtaatataaa atgtagttac tggtgtagct tttcctgttg aattgataag gcactttcat     2160

tttgcacctt tttctttaaa ttaaatgcta gcgtgttcac tgtcgtgtcg catgtgcacc     2220

agaaacacaa gtttaactga gaaggcttgg aaggtacgtt gggaggtatt tatgctgctg     2280

tttacaaaat tatttttaag agactggctg gtcatatcta gaaatcacca cgttggattt     2340

tttttttaac atgtgaattt ggaattagaa acggaactct ccctaaatta tactttgctt     2400

tttggtaagt ttaatgatag atgtgtttat gcttcataca aagttgaatg attgattggc     2460

gtggtggaca tataccatca tgctcatttt ttttttttaa agctttttaa aatgccacct     2520

catggaggcg agggggagga gaagctcatt ttacacaatt cagtagttaa atatggactc     2580

ggtctcaact tggaattctt atgctttgag aacaaatcaa caaccagaat atttattgga     2640

atctagcttt tattataaga aggacccaaa gattatatcc tgagcaaatg cacactcccc     2700

atgtgaggac atgaagtatt tactttgtga atgtttatgt tcttggtata atctaggaac     2760

cctatgagtt tatctcagag tgaactaatt ctagatttgt tgtcaataga tgctataatt     2820

caagaatgtt gctctccata tttgaaaaac gatggatagg agggtgaggg aagcatacaa     2880

tgttgaacca gtttctctta tttaaatatt aaatacttta agcctttaaa gtgaagttga     2940

tgctagctgc aaacatttac tcttgtattt atcttcacta ggaaactgtg gactgtaatt     3000

tattttatta aatatttaga agattatttg gcttgtgtgt tcaggtgaga aatactgagt     3060

tgtttttgtt taatttcatg gttttttttt ttttaatgat ccctagtggg ggaaggggaa     3120

aggaatagtc tgataaacag atgtgcatat tttaaaaaca agtgaccttt tgggaatgta     3180

ggcatttaga cgatgatttt agtcgcacta ggggtgggat tcaaactact ggtcaaagac     3240

cattttgtac agaaaaggga acatctccga tgggtgttaa ggtaggagtt tccatgcagc     3300

cctttatgtc tgagaaatag tctcctctgc cattggggtc cctgcggaat cttctacagg     3360

aattgcagct cttcacgtca tgctaggtta ccagcatggg cttcccagag cacttcactc     3420

tgtttctaac tccactgact tttctgactt gtttcttgag ggacttggaa aaggggaagg     3480

tattattcac acagatgtgt gtatgaagcc taaataacat ccaacttttt ttccaaaaac     3540

atagtaagag tttaaccata aatagaagag taatattcct ttaaatttct tacaggcatg     3600

taaaatttta tgtgtttata gagagatgct aactgtcagc atatagtatt tatattgggg     3660

caagaagggt taaatcaaat ctttaattta agtaagcata gttcctttaa agatcagtag     3720

tatttatact ctgaaaagag taccaagctt agttcagtta tttattcatc catttttttt     3780

ctattgtttc tcctctgggg ggaaatggtg ttttgttttt gtttgagttt tgtgttttag     3840

ttttttggtt ttggttttgt tttgtttttt tgtcattcag attcactaaa tttggggatg     3900

gttttattaa agtatattaa cttcttttta accaaagctt tctgaatatg accagcctca     3960

ggtgctagcg cattaaagag caactaaacc taattccagt gtcgatttgt gaaataataa     4020

aagctaattg aatttctcta agggtgagag agaacataat gatgaactta aaaagaaatt     4080

ccttttccca gaagggattc tgcatgtacc tacaaacaat catgctctaa ccacagtaat     4140

agtcatgcca tggtgacatt gcttttacgg taaaccaaga taggtaatat gatgcttctt     4200

cccaggtgtt tctgaaagaa aagcagcggt ggagcttaag agccaagtcc actgattgac     4260

ataataggat ggaattgtag acagagacat gctccatgaa acaaggaaac aactgactac     4320

tatttggatc taagttggga tctgatgtta aacaataaat tcagtttaaa aaaaatatgg     4380

agctcagaaa aggatgtgaa aaactttgca ttttcctttc ttcattatta caaaaacacc     4440

tatgtgatga cataaaatac ttgggtgata tcagaacaat tatccttaat agtttttata     4500

attaaagttt cctaaacttc agtctccaat agtcttttaa ggattggaac cacatcactg     4560

tcagccccgc tgctacaatg cctttgtaca atttttttac ataaggcaaa taaggctttt     4620

gtacaaagcc tgaatacctt ctgttccaat ggtgtccaaa tggttattat attgtgaaaa     4680

acctggcctt ggtcacaatg caaacaaaag tacagatgaa agtgcttttt ggacagtttg     4740

caaattgtgt taaagctacg gatttttttt aaagtgttca gcatcttaac gtgtattaaa     4800

gctatggatt tttttttaaa gtcttcagca tcctaattca ccctttctaa cttaagaaaa     4860

acatgactta agacactgct tctaagtttg gttgttcttt atagtgtgga tacccagtta     4920

tctgtgagcg tatgggggtg ggctgagggt caggtgagga aggagtgtgt gtgtgtgtgt     4980

gtgtgtgtgt gtgtgtgtgt gtgatttgca tgtgtatgat gtgtgtgcgt cggaccgctt     5040

ctaggctact aagtgtcaat ggaaaagaaa atgtattcaa aatacttaaa tcaaaactag     5100

aagatgggga aaaaaagatt tattctatac aaagccttgt ctggaccact ttagagagac     5160

ttctattttt ttaacccttc tataaatatt tgatggcact tgaaatattc ctgcaataaa     5220

atgtgatttg tgtaaagaaa aaaagatttt gtaatgtgaa acaaagaaag aaagtaatgt     5280

aattttctaa aaaaaaaaat acaaacaaac aaactttgta ttattttctt gatggaattt     5340

gtctatctgt ctttggaaaa ctttttattt cattgaatgt gccatagtag aaatgtgtgt     5400

ttttagtttt agactaagga atagctagtt gttgtgttcc gacattccaa aatgcaaaac     5460

aacctagtag tatctttcat gaaaaggttt aagtagtatg taagcttctc tcattgttgc     5520

ttttttgcac atgttcttca ttcctctcta gtgcaatatg tacatagagc acttgcgggt     5580

gtaccttgat ccctcaggga aaaatacata tttgtacagt tttttggggt ttttttgttt     5640

tttggttttt tttgttttgc cttttgtttt tggctaagga atgtcgatcg aatcacttgt     5700

tattgttgag gggcagccag ataataatcc taaagccact gtttccaaca ttgattgttt     5760

aaatcatatg tccttccaat gctattattt taagataata ataaaaagtt attttctgac     5820

agttctttgt gctgactggt gaaaaacaag ggtaaataag caccttataa ttgacttact     5880

gtgaatgaca atccatcttg gtatcaacga tagaagccct atcattttgg agttggggtt     5940

aagagtcaga aacaatgtgc tcagggatct cctaaaactc ttaaaacagg gtggccagta     6000

ctactgggac aaattgtgtt ttttattatt aataataatg ataataatac tatccctcca     6060

aggcacaagt gaactatata gaactgcgtg tgtgtaaact ctttactctc gtctcatttt     6120

gttgagttta gaacttgatg tgctcgtcag tcttgtgttt caaaacactg aataacttcc     6180

aaagcaaagt tatgccagtg tgttcaaaag ataaattaat aatgtaccag caaagagcat     6240

cattcaaagt atagtccttg catattccag ttaccatttc tctaataatt aaaatattca     6300

tgataaatat atatatagca tcatatgtta aaaactattt caaattctac atattaagga     6360

tgaaaatttt aaaatccagt aataagagga gagacctgcc tatcagtaca gtgatatagg     6420

taaaagatga aatatgtttt taaaatacca gcaattaact attgttttca tgggttctcc     6480

tctagaagca aaccaaaaat tccttcatgg aaaacaattc ttacttctac atgtgtagtt     6540

tatatctgat gcattacaag agctaatgtt taaagacaaa acaaaacctg cctgtatgac     6600

agcagcaact cgagccaaca tttagtgtta catgttatat ttttgaaata ccgttttgtt     6660

atcatattcc acatattact ttccataaag tcagagaagt tcaatgtaat tgttggctct     6720

gattcttcca ccttgggata cacattcaca agaagattta tatattttct tactatgata     6780

gaggaacata atctgggaaa acttcccatg tctgtaagat gaaaaggata cctttaccat     6840

gttgtttttg ataataaaga atatggaaaa tggtagaaat ctctcctctc tatgtgtatt     6900

tgtatatgtg tgtatacaca cacacgttga catttttaca taacatgtga ttgccacttc     6960

ttataaagtt atgatataga accccatgaa aacaacttta tattatagat caaataatgt     7020

gcccagaaac gcaattgcaa cagtaaatct tgatctattg gtaagagtct atgatacagg     7080

tcttcattct atccctaaac ataatgttag taaagaggtt ccatcagatt gtattataga     7140

gaccttccta ttgctattta tttttaagag atgagaagac tgactagcaa tgtctccaca     7200

gtgcaattgg tttcacttct gggtctgtct gtctgtttgt gtaggtgaga tcagtgttgt     7260

caggctctca gaataatttt taaaagaatc cagaagcctg acttcacacc aagtagccat     7320

cctagatggg cgggggggat ctccatgttc aaccaaaccc tcagaactta gagcaataaa     7380

tacattcagt catttattta taaatgaatg acagaatatt caatccaaat agaaacaacc     7440

ttttgtcagt gatgcaacat aacatggagt cttatattga gaaagtgaat atgaatattt     7500

taaatagatg cctaggaaat ctgtgtttgc tgtttacatt taatgtactt tgccacatta     7560

gcagtaccac acttctttta ctttcatcct tctaagaact aatgaaagat agcttgctat     7620

tagctttgac atgttgcaca tgccattatg ttgttctcta agaacaacta aattctctcc     7680

agtgttcatg tgtgattcct ttttcatcat tattacttta atgtggatga atactatttc     7740

taggaacttg attatcactg aacagattgc atatgtaaat gcagataatt cttgagcaat     7800

atagtgaaaa tgatttcaca aaaaaaatcc atatgtactg tatacatctt cctgaatcca     7860

aaattctcct gttatccaca cagtttgaaa tctcatatta aacagtggta aatttttaaa     7920

cattaggaca ttagctggct gcttctataa atgtacctgt attgtctgcc tgctcctttt     7980

gtggagatgt gtttttgtat tggatgtttg ggccaatggg aggcttcaag ctacaacata     8040

ttttcccact ttaaataata tttaacatat gacaaacccc agacaaggct tttaatatgt     8100

ataaagaact gcagtgttag gtggtttatt tgcaaactgt tttcagtgtt gtccattttt     8160

atggcacctt taacaatatt cttgtttcca aagtacaaaa aaaataggtt aaataatcta     8220

gccataactg aatgtcaagc aataaaacaa atgacttttg tgcatagact taaaaaatac     8280

aaattttaga catctgcatg taaatgcaat ctcttgttta ctgctttctt caacttgagc     8340

aatcgattcc ttatttacta ttaacttaag aacttgtaac ggcctgtaaa cattttctct     8400

cttactcttc tttcaaattt acctgtccct gcttttgagt cataatattt aatgttgttc     8460

tgcacatctc tatacagtta actttttggc tttcattctg tatagataag aaaatgttat     8520

attataaaca gcctactcag tgcaaatatt tatctgttta tcaaatccac aatatgctgt     8580

ataataccgg ttttactata taatctattt tagacatagc tgtttagaac tagagtgtgc     8640

tatttttgtg tttttctgat gtgtggtgct agacaagtta cttttgtgaa caacaaaaat     8700

tatccctttt attcctagac aataccacct ttgggtcttg ttaatttcac tgagtataac     8760

tatatatttg tatatatata catatatata tatatctacc tatgcccaac tggcagctgt     8820

atcagagtgc tggatttggg acatgctttt ctctttaaat acataatatc attatataaa     8880

ttattctaga gtgtatttaa ttaggataaa attacttcct tagtatggat atttgacatc     8940

tatagggtga atttgtttat aaatatggct atatggaaac ttattagcat ttactttatg     9000

tttgctactt ggctttacag catatctcct aagctgaaaa ataatttgcc aggccttcaa     9060

gatcctaaag aaacttgttt aatggagtaa tatacttttt tttcttatta aggaattgta     9120

ttactggcac ctaacacagt tgtattctta gctcctatta tagataatgg gcatttacat     9180

aaaatatcct agatggcttg atggcagaat aaacctttcc cctcctacct gagtcatgag     9240

aaggatggag acgtcctctg ccataacatg ggccataaag caaattcgac atgggatgtt     9300

ctgtttcagt atgacctcaa ccagttccat gaactgagtg aaggaccttc attttcaaag     9360

ttatttaata agtagcttaa ttaagccttt ctacccattc tcccaagatc tactggcatt     9420

attgaaaagc aaagtttatc aaatatctaa ctaaggatgt agttaacctt attaaatatt     9480

gattagaatt gttctgtaat attactgaat ttgtaagatc tttagcaaag atttttgagc     9540

aatttataaa tgtagagcaa atgtttctgt ttactgcact ttttgtaact gaaggtgata     9600

aattctcaag ccatgattat tggcttccat gcactgcaat atttatccac aattctagac     9660

attttccatt tttgtggaag agttgctgtt accttaatta taaatgcaat tgtgtggtta     9720

atgagagcta atgctagtag ttaacctttt aaagtggatt ggctacagtt gagggagaaa     9780

tctcttttaa tataaatcac atcattcctt aactgcctct cttggaaaga gattgaaacc     9840

ttttttttaa agcacgattt agcatcctaa gcttcctgag ggtagagatt gtatcttttt     9900

gcgtctgcac aatggctagc acatgtcagc atttgacaat tgttaaatga taacaagtgt     9960

gccccaatta aaacgttttt cctgggttgt tttgttaaat ttacaaagta agccaagcct    10020

tacggttaac attctcctct acaaccaagt attaaagcca catttaaaaa gaccacatga    10080

aatgctgatt ctaattgtgt gtaggtcttg aggattaagc acacaaattt cacaaacttc    10140

tgtttgagta aacaaactca gccttctgta aatatacatg caagtttgga aacagtaata    10200

ctgtacctat aaatatatgc tgtctgtttt gtgtacagta tgtaaaaact ccttttctgc    10260

cacactaaaa atgcaagcca tttatgggaa tcctaaaact agtattgaac taaaactttg    10320

ctaatgatct ttattagagg atcgtccaac ttttcactta ccttgggttt tcttttcaat    10380

tcactcttac actagtctgc ttatttccag ctgtttattt tattgagtcc tgaatttaaa    10440

aaaaaaatat tttgattcat tttgtaaata caagctgtac aaaaaagaga gatttaatgt    10500

tgtcttttaa atactccaat tttcattcta atatgaatgt tgttatattg tacttagaaa    10560

ctgtaccttt aatattacat tacctttatt aaaagtgcat tgaacacatc aattttagat    10620

gtgctttatg tactgttatc ctataataaa acttcagctt ctaatggaa                10669


<210>  2605
<211>  7218
<212>  DNA
<213>  homo sapiens

<400>  2605
agctgagaac aaagttgaaa gtttgcctgg agctccatgc cactccccgc ctgggccact       60

gctttgtttt cttctaatgt ttttcctcta cctgggttgg ctgtttcttc attcatattt      120

gagaagaatc acctcctaat taaatgtagc acttcgctct ctccctacat gaaggctgtc      180

ttggttaccc gactaggcaa cgcgcattgg tatcaaatta ccgaaagtct acaccggagc      240

agtcctcata tttacataca aataactcag gggcttgcat ttatgtcacc attctgtcct      300

gctagaggct tgccagagga gtttttaatc caatcagaag gagctttaaa aggatgtctg      360

cgaagtggtc aaaaggatct taacctcaat taagtggggt tttttaaaaa gatttttttg      420

ggggcctgaa attttgaaaa tcttcgaact ctgagtgggg aaagatgtat aattcctcaa      480

ttgcctacga ggatatcaag atgctgagag gaattcagcg gtggtgaaga gagtggatac      540

aaaccaggga ttggtttcct tgagctgttt tggaggttga ttctaaatca ctgcttaagg      600

aattcctgga aacatcagga aaacatttga tcatccaagc ctagtggaaa tggctttacc      660

gcagagtgaa gatgcaatga ccggggacac agacaaatat cttgggccac aggaccttaa      720

ggaattgggt gatgattccc tgcctgcaga gggttacatg ggctttagtc tcggagcgcg      780

ttctgccagc ctccgctcct tcagttcgga taggtcttac accttgaaca gaagctccta      840

tgcacgggac agcatgatga ttgaagaact ccttgtgcca tccaaagagc agcatctaac      900

attcacaagg gaatttgatt cagattctct tagacattac agctgggctg cagacacctt      960

agacaatgtc aatcttgttt caagccccat tcattctggg tttctggtta gctttatggt     1020

ggacgcgaga gggggctcca tgagaggaag ccgtcatcac gggatgagaa tcatcattcc     1080

tccacgcaag tgtacggccc ccactcgaat cacctgccgt ttggtaaaga gacataaact     1140

ggccaaccca ccccccatgg tggaaggaga gggattagcc agtaggctgg tagaaatggg     1200

tcctgcaggg gcacaatttt taggccctgt catagtggaa atccctcact ttgggtccat     1260

gagaggaaaa gagagagaac tcattgttct tcgaagtgaa aatggtgaaa cttggaagga     1320

gcatcagttt gacagcaaaa atgaagattt aaccgagtta cttaatggca tggatgaaga     1380

acttgatagc ccagaagagt tagggaaaaa gcgtatctgc aggattatca cgaaagattt     1440

cccccagtat tttgcagtgg tttcccggat taagcaggaa agcaaccaga ttggtcctga     1500

aggtggaatt ctgagcagca ccacagtgcc ccttgttcaa gcatctttcc cagagggtgc     1560

cctaactaaa agaattcgag tgggcctcca ggcccagcct gttccagatg aaattgtgaa     1620

aaagatcctt ggaaacaaag caacttttag cccaattgtc actgtggaac caagaagacg     1680

gaaattccat aaaccaatca caatgaccat tccggtgccc ccgccctcag gagaaggtgt     1740

atccaatgga tacaaagggg acactacacc caatctgcgt cttctctgta gcattacagg     1800

gggcacttcg cctgctcagt gggaagacat cacaggaaca actcctttga cgtttataaa     1860

agattgtgtc tcctttacaa ccaatgtttc agccagattt tggcttgcag actgccatca     1920

agttttagaa actgtggggt tagccacgca actgtacaga gaattgatat gtgttccata     1980

tatggccaag tttgttgttt ttgccaaaat gaatgatccc gtagaatctt ccttgcgatg     2040

tttctgcatg acagatgaca aagtggacaa aactttagag caacaagaga attttgagga     2100

agtcgcaaga agcaaagata ttgaggttct ggaaggaaaa cctatttatg ttgattgtta     2160

tggaaatttg gccccactta ccaaaggagg acagcaactt gtttttaact tttattcttt     2220

caaagaaaat agactgccat tttccatcaa gattagagac accagccaag agccctgtgg     2280

tcgtctgtct tttctgaaag aaccaaagac aacaaaagga ctgcctcaaa cagcggtttg     2340

caacttaaat atcactctgc cagcacataa aaagattgag aaaacagata gacgacagag     2400

cttcgcatcc ttagctttac gtaagcgcta cagctacttg actgagcctg gaatgagtcc     2460

acagagtcca tgtgaacgga cagatatcag gatggcaata gtagccgatc acctgggact     2520

tagttggaca gaactggcaa gggaactgaa tttttcagtg gatgaaatca atcaaatacg     2580

tgtggaaaat ccaaattctt taatttctca gagcttcatg ttattaaaaa aatgggttac     2640

cagagacgga aaaaatgcca caactgatgc cttaacttcg gtcttgacaa aaattaatcg     2700

aatagatata gtgacactgc tagaaggacc aatatttgat tatggaaata tttcaggcac     2760

cagaagtttt gcagatgaga acaatgtttt ccatgaccct gttgatggtt atccttccct     2820

tcaagtggaa ctggaaaccc ccacagggtt gcactacaca ccacctaccc ctttccagca     2880

agatgattat tttagtgata tctctagcat agaatctccc cttagaaccc ctagtagact     2940

gagtgatggg ctagtgcctt cccaggggaa catagagcat tccgcagatg gacctccagt     3000

cgtaactgca gaagacgctt ccttagaaga cagcaaactg gaagactcag tgcctttaac     3060

agaaatgcct gaagcagtgg atgtagatga gagccagttg gagaatgtat gtctgagttg     3120

gcagaatgag acatcaagtg gaaacctaga gtcctgcgct caagctcgaa gagtaactgg     3180

tgggttacta gatcgactgg atgacagccc tgaccagtgt agagattcca ttacctcata     3240

tctcaaagga gaagctggca aatttgaagc aaatggaagc catacagaaa tcactccaga     3300

agcaaagaca aaatcttact ttccagaatc ccaaaatgat gtaggaaaac agagtaccaa     3360

ggaaactctg aaaccaaaaa tacatggatc tggtcatgtt gaagaaccag catcaccact     3420

agcagcatat cagaaatctc tagaagaaac cagcaagctt ataatagaag agactaaacc     3480

ctgtgtgcct gtcagtatga aaaagatgag taggacttct ccagcagatg gcaagccaag     3540

gcttagcctc catgaagaag aggggtccag tgggtctgag caaaagcagg gagaaggttt     3600

taaggtgaaa acgaagaaag aaatccggca tgtggaaaag aagagccact cgtaacagcg     3660

aacggtcagt caaggatcat aagtttttac tgccagtatt gagaaattcg tggaagaaat     3720

gtcagcagga agtaaaaatt caccgagaag tgtgtgtgtg ttcgctgctt ccacacatta     3780

atggcatgat tttttttatg caaaaagaaa agaaaagaaa accacccaca ttttaattta     3840

gcatgagcca atttacagag catggaaatc actttcattt ccggattggc gcgtgtgcaa     3900

ttagcaatgc agtgtatata caagaagcca tgctgttaac agtttatctc aagtaatttg     3960

gtgtcattta caaaaggaag aaattcctgc catcagaagg gacagaagga gatggaatga     4020

tcaaatcaca gagaaacact aaaattacta aatctacaac agctcgcctt atttttcttg     4080

gacccaaact gtcagggtat aaacactatt tgtttctttt ttaaaacatc gatagttttg     4140

ctgtaaataa taacactgta taaattctaa cagaaaaata gaataaaatg ttgataaggc     4200

actgcctctt agaacacaaa cagaatattg caaatgcatt taacaaatag gggtctcaag     4260

tgacttcacc ctagaagagg agggagggat tctgggtggg ggtgactctt cactgattct     4320

tgtatattag caattataat gtttgtatat gcaaaactgc tagcttgatt ttaaaaaaaa     4380

acaaatcttt aaaatctgct gcaaatttaa ataattccca aaatgaggaa ttctgtagtt     4440

ctgtgaaaaa tttttttctt cagaatacta atattttgat gcatgtgtat caccttattt     4500

tgattaaatc ttttccaatt ttgcaaacac tacagtatac tgcaacacaa aagattttat     4560

ctgtaaacac aaagcccttc atctaatatt tgttgctatt gccaattttt caatgaaatg     4620

acctaaaaac aacaaaaaaa aataacctat acggtagttg ctttaggggg tggggggatg     4680

ctatctgtta gtgcttaaaa gggggtaaat gcttgccgct ttagaggtgg atggtgctca     4740

taaaaggccc cagtcggggg tatttaaaaa ggactgaaca gaaatcctta gctagtagaa     4800

tggcagcacg ctgtaaaatt attactgtat tgtgtactgg ctataagatg tagacacctt     4860

tcagtaagcc aatcatttgt aaccattcta gcagtgtcat attaggttaa taaggctgct     4920

gtgttttaaa gggcattttt atttgggttt tggtgaaatt ctttaatttg ttgattatat     4980

tcacataaaa tcagcattca ttgacacata gctctaatga catatgtatg aaaaaccata     5040

cactggatga cctagtcgat tatttaagca taaaataaat tgtgttaaac tcttcaccta     5100

tctgtgctct acagtctcct tgtgttttct ggcaaaaggt agttgtctaa tcccttgtca     5160

tatgagtcct ggccaatcca ccccattggt cctctttgtg cctctgtggt cactgaagag     5220

ataatctcta acattcatat gtgccctgca agctcccagc ttataaattc tgtgcatttc     5280

atgggggagc caagaattaa agattaattg acaagtaagc tttgcccaca tctgttcagg     5340

ccttcttgaa aagtgaagaa ttggagatac tatagccagc atgtcaaaaa gttgactggc     5400

acttctagga accatcaaca tgcagttgct tttagcccac agagcttgtt tttgttttgt     5460

tttattaatt tacatttatt gtccattctt acaagttggg acatttcaca taattaagtt     5520

gctaacatct cttaaaaagc aagatttggc aacaatggac ctcattccca gaaggtaaca     5580

acctgctaga gccaagttgt ccctgccctc tccagccagg tgtggggtct acaggtatca     5640

ctgccacagc ctcatttctt atatttgtac aacctgactg tgaatttgca acccatacac     5700

tgcgtgaatc taaattctac tgaggcagag accatggctg ttttaacttt tattctagtt     5760

accagcttag catatggtag tagtgatagt agtaactgtg atcatcatca ctaaaactgg     5820

agtgctcact acatgctatt ctctgttcta agcacattcc atttacttac ttagtcctca     5880

tatctacttt atgaattagg tactgtcttt ctttgatggt aatgatcctt ttataaaatt     5940

aaattagtgc taagagactt tcagcaatgt tatatattgc ctgtccatta aagattgttg     6000

ccaaatggag tgagttgtcc ccagtaagga ttcactatca atgcagaaga aatgcacgga     6060

taatctactt tgcataaaga atggggctag gttgcatctg catggtatcc caaataaata     6120

aaatgtgcca ctacccttgc accaaaatta ttttatgatg ggtaaagtta gacccttgag     6180

aggttttttt tttaaaaaaa aaaaaaaaaa aaaactttcc caaaatgcct ctctgtaaag     6240

ccaggatcag aatataggtg tcctaacttc ctatctaaga gttacgaatt tctgactcag     6300

tctttgagag aaggtgttta tcctgaacca gaaactcaat gatgtatacc tgtttaggta     6360

ttaaatagtt gtgtttatat gcccaaaaat ttgactttag gtatatgtga tatgctttgg     6420

ttccgatcaa gcaggaggtc ataagtttac tcagaagtat ccaaaatatg acattcaaga     6480

tttaacttgc atatgtgtgt atatgcatat atttatacat gtatatgtag attgaatgtg     6540

acattatgta tttctaacat aatatttggc ctgccagctt ataaatatgt atttaagctt     6600

ttcattgatt gacattactg taaaaaatga attatgattg agaagttctg gatatttgct     6660

gtttttttca ttttatattc ttactaaatt attgaatttg ttaaattaaa atgtgctatc     6720

actgtattgc caaattatgg caatacacta tgcagtatta tttcaatact ttaagaggca     6780

tctattactt cattgaacac ataagcagct agcctccttt cctctgtaaa taaggacttt     6840

ttggcatcct gatgttcctc gctgttcatt tggtatcatc ctggagttcc atcaagactg     6900

aggattttct ccatggccaa taaactattg tcagcatcag ctcacgtttg gctgtatgac     6960

agggatatgt gagaagccca gaaataaatc acaaaaataa taaggcatct tctgagtctc     7020

tctgaagaag ccagtgatcc aaaaactaac ttcatatctg agtgagtctt ggtattcttg     7080

atttgcttga agaggctgtg acatattaca aggtgtgtaa tttcccaggc atatcacact     7140

gcttctgttt catgaattga tcaaattgtc cagaagtaaa catttacaag attgagattt     7200

gaaaaaaaaa aaaaaaaa                                                   7218


<210>  2606
<211>  2731
<212>  DNA
<213>  homo sapiens

<400>  2606
gcactgcctc tggcacctgg ggcagccgcg cccgcggagt tttccgcccg gcgctgacgg       60

ctgctgcgcc cgcggctccc cagtgccccg agtgccccgc gggccccgcg agcgggagtg      120

ggacccagcc cctaggcaga acccaggcgc cgcgcccggg acgcccgcgg agagagccac      180

tcccgcccac gtcccatttc gcccctcgcg tccggagtcc ccgtggccag ggattattgg      240

acctgcctgg tttaaactat tgtcttagtt aattttgtgc tgctctaaca aaatatcaca      300

gactgagtaa tttataagca atagtagctt atttggctca cagttctgga ggctgagaag      360

atcgtgaggc tgcatctggc aagggccttc ttgctgcttc ataacatggc agaagacatc      420

atgcgggtgt gtgtctgggg aagagactta cagaagtgga gttgctgagt caaagatcta      480

accatgagct accctggcta tcccccgccc ccaggtggct acccaccagc tgcaccaggt      540

ggtggtccct ggggaggtgc tgcctaccct cctccgccca gcatgccccc catcgggctg      600

gataacgtgg ccacctatgc ggggcagttc aaccaggact atctctcggg aatggcggcc      660

aacatgtctg ggacatttgg aggagccaac atgcccaacc tgtaccctgg ggcccctggg      720

gctggctacc caccagtgcc ccctggcggc tttgggcagc ccccctctgc ccagcagcct      780

gttcctccct atgggatgta tccaccccca ggaggaaacc caccctccag gatgccctca      840

tatccgccat acccaggggc ccctgtgccg ggccagccca tgccaccccc cggacagcag      900

cccccagggg cctaccctgg gcagccacca gtgacctacc ctggtcagcc tccagtgcca      960

ctccctgggc agcagcagcc agtgccgagc tacccaggat acccggggtc tgggactgtc     1020

acccccgctg tgcccccaac ccagtttgga agccgaggca ccatcactga tgctcccggc     1080

tttgaccccc tgcgagatgc cgaggtcctg cggaaggcca tgaaaggctt cgggacggat     1140

gagcaggcca tcattgactg cctggggagt cgctccaaca agcagcggca gcagatccta     1200

ctttccttca agacggctta cggcaaggat ttgatcaaag atctgaaatc tgaactgtca     1260

ggaaactttg agaagacaat cttggctctg atgaagaccc cagtcctctt tgacatttat     1320

gagataaagg aagccatcaa gggggttggc actgatgaag cctgcctgat tgagatcctc     1380

gcttcccgca gcaatgagca catccgagaa ttaaacagag cctacaaagc agaattcaaa     1440

aagaccctgg aagaggccat tcgaagcgac acatcagggc acttccagcg gctcctcatc     1500

tctctctctc agggaaaccg tgatgaaagc acaaacgtgg acatgtcact cgcccagaga     1560

gatgcccagg agctgtatgc ggccggggag aaccgcctgg gaacagacga gtccaagttc     1620

aatgcggttc tgtgctcccg gagccgggcc cacctggtag cagttttcaa tgagtaccag     1680

agaatgacag gccgggacat tgagaagagc atctgccggg agatgtccgg ggacctggag     1740

gagggcatgc tggccgtggt gaaatgtctc aagaataccc cagccttctt tgcggagagg     1800

ctcaacaagg ccatgagggg ggcaggaaca aaggaccgga ccctgattcg catcatggtg     1860

tctcgcagcg agaccgacct cctggacatc agatcagagt ataagcggat gtacggcaag     1920

tcgctgtacc acgacatctc gggagatact tcaggggatt accggaagat tctgctgaag     1980

atctgtggtg gcaatgactg aacagtgact ggtggctcac ttctgcccac ctgccggcaa     2040

caccagtgcc aggaaaaggc caaaagaatg tctgtttcta acaaatccac aaatagcccc     2100

gagattcacc gtcctagagc ttaggcctgt cttccacccc tcctgacccg tatagtgtgc     2160

cacaggacct gggtcggtct agaactctct caggatgcct tttctacccc atccctcaca     2220

gcctcttgct gctaaaatag atgtttcatt tttctgactc atgcaatcat tcccctttgc     2280

ctgtggctaa gacttggctt catttcgtca tgtaattgta tatttttatt tggaggcata     2340

ttttcttttc ttacagtcat tgccagacag aggcatacaa gtctgtttgc tgcatacaca     2400

tttctggtga gggcgactgg gtgggtgaag caccgtgtcc tcgctgagga gagaaaggga     2460

ggcgtgcctg agaaggtagc ctgtgcatct ggtgagtgtg tcacgagctt tgttactgcc     2520

aaactcactc ctttttagaa aaaacaaaaa aaaagggcca gaaagtcatt ccttccatct     2580

tccttgcaga aaccacgaga acaaagccag ttccctgtca gtgacagggc ttcttgtaat     2640

ttgtggtatg tgccttaaac ctgaatgtct gtagccaaaa cttgtttcca cattaagagt     2700

cagccagctc tggaatggtc tggaaatgtc a                                    2731


<210>  2607
<211>  2928
<212>  DNA
<213>  homo sapiens

<400>  2607
cggcggcggc ggcgcggcgc agggcgcggg gcggcatggc caccaccgcg cagtacctgc       60

cgcggggccc cggtggcgga gccgggggca ccgggccgct tatgcacccg gacgccgcgg      120

cggcggcggc ggcggcggcg gccgcggagc gattgcatgc aggggccgcg taccgcgaag      180

tgcagaagct gatgcaccac gagtggctgg gcgcgggcgc gggccacccc gtgggcctag      240

cgcaccccca gtggctaccc acgggaggag gcggcggcgg cgattgggcc ggcggcccgc      300

acctagaaca cggcaaggca ggcggcggcg gcaccggccg agccgacgac ggcggcggcg      360

gcggaggttt ccacgcgcgc ctggtgcacc agggggcggc ccacgcgggc gcggcatggg      420

cgcagggcag cacagcgcac cacttgggcc cggccatgtc gccctcgccc ggggccagcg      480

ggggccacca gccccagccg ctcgggctgt acgcgcaggc ggcctacccg gggggcggcg      540

gcggcggcct ggccgggatg ctggcggcgg gcggtggcgg cgcggggccg ggcctgcacc      600

acgcgctgca cgaggatggc cacgaggcgc agctggagcc gtcgccgccg ccgcatctgg      660

gcgcccacgg acacgcacac ggacatgcac acgcgggcgg cctgcacgcg gcggcggcgc      720

acctgcaccc gggcgcgggc ggcggcggct catcggtggg cgagcactcg gacgaggatg      780

cgcccagctc ggacgacctg gagcagttcg ccaagcagtt caagcagcgg cgcatcaagc      840

tgggctttac gcaggccgac gtggggctgg cgctgggcac gctctacggt aacgtgttct      900

cgcagaccac catctgccgc ttcgaggccc tgcagctgag cttcaagaac atgtgcaagc      960

tcaagccgct gctcaacaag tggctggagg agaccgactc gtccagcggc agccccacca     1020

acctggacaa gatcgcggcg cagggccgca agcgcaagaa gcgcacgtcc atcgaggtgg     1080

gggtcaaagg cgcgctcgag agccactttc tcaagtgccc caagccctcg gcgcacgaga     1140

tcaccggctt ggcagacagc ctgcagctgg agaaggaggt ggtgcgcgtc tggttctgca     1200

accggcggca gaaggagaag cgcatgaccc ctgcggccgg cgcgggccac ccgcccatgg     1260

acgatgtata cgcgcctggg gagctagggc ctggcggggg cggcgcatcg ccaccctccg     1320

cgcccccacc gcccccgccg gcggcgctgc accaccacca ccaccacaca ctgcccggct     1380

cagtgcagtg accccgcggg ccgggccccc gccggcgcgc tgcagggcgc gggcgcgcag     1440

cccgcccgcg cggcctggac tctttttgtt cggttgcttt ggattttaca aaaaaaaaaa     1500

aaagcccaga aactttcgaa caaaaccaaa cacccggacg accctctccg gtgagcggcg     1560

aagacagccc ggtaggctgc gtcgcccgag ccccgggaga gaggagcgaa gatccggaac     1620

tcgccaactc accccgggca tcctgcccgc cgcctgctct ctgcccccat cccctcgacg     1680

acccccgccc ctgccccccc gggctgttcg gggccggatc ccggcagcgg cctccccaaa     1740

gcgacaggta acgcagtgcg gggttaggga ttccccggga gagaggacga agcgaggaga     1800

gttctccatc ccctctcccc gcgtggactc ctgagcctgc gggtccaggg tggggggctg     1860

tcactttatt cgctacacgc ctcttctctc ctataaggat gcgccccacc ccgctttccc     1920

ctttctccgg gcttggtttt ttacggtttt tatttattcg tggagcctct cggctcctgg     1980

ggtccttcta actccgcccg cgcccttaat ttaaatcgca gtatactgta tttatcgggg     2040

ccccggaggg gaggtcgcga gagccgcgtc tgtgtataaa agcaggaaat agccaaagct     2100

ttaatctagc ctaatttatt tttcccctta tatttcccta ccctaccctc cccccaaaaa     2160

aaagcaaaaa aaaaaaaaaa aaactaacaa aaaaaattcg agtgttcatt tttcgtttcg     2220

tttcatccga gccccggctt ggttcccggc cacgccggag gggtctgcgc tcccacacac     2280

ccagacggga aggggcttct gccctgctgc agaccgaccg ccgcatagcg cggcccctgc     2340

tccccgcggg gccctgccct cctggccaca ccaaacgaaa cttggaaaag ttagagagat     2400

tgttttttaa ccagctgtag aaataagccg ttccctgaga accctccgcc tgattccctg     2460

cagcttccct ctgctccctt tccagcccgc cgggatgcgg gatgccaggg gaggccggga     2520

gagaaattcc ccaagtttgg ggtgaggtgg gaaccatgta aatatgtgag atatgtacac     2580

actggcgggg agaagaaaca ttttgtgctt ggtttttatt tttggttttc cgggttaccc     2640

ttccttccta ccctaaagga ttttgtacac tgactaatcc gaaaaagata ttttaatatg     2700

atttccgaat ttctgaccca tctctattta ttttctggat gtgtttggag cttccccctt     2760

ctccgtttct tcttctgttt gttaaggttt gaatttaaat tttgttattt tatttttatt     2820

attttttgaa acaatgtttc ggtgcattct ctttgtatct ttattgaaaa aaaaataatg     2880

tagactggga agttcccttt atatttatgt tatagtaaat attttatt                  2928


<210>  2608
<211>  1682
<212>  DNA
<213>  homo sapiens

<400>  2608
gcaggaccgt cattgacgcc atgagcgcgc tgctgcggct gctgcgcacg ggtgccccag       60

ccgctgcgtg cctgcggttg gggaccagtg cagggaccgg gtcgcgccgt gctatggccc      120

tgtaccacac tgaggagcgc ggccagccct gctcgcagaa ttaccgcctc ttctttaaga      180

atgtaactgg tcactacatt tccccctttc atgatattcc tctgaaggtg aactctaaag      240

aggaaaatgg cattcctatg aagaaagcac gaaatgatga atatgagaat ctgtttaata      300

tgattgtaga aatacctcgg tggacaaatg ctaaaatgga gattgccacc aaggagccaa      360

tgaatcccat taaacaatat gtaaaggatg gaaagctacg ctatgtggcg aatatcttcc      420

cttacaaggg ttatatatgg aattatggta ccctccctca gacttgggaa gatccccatg      480

aaaaagataa gagcacgaac tgctttggag ataatgatcc tattgatgtt tgcgaaatag      540

gctcaaagat tctttcttgt ggagaagtta ttcatgtgaa gatccttgga attttggctc      600

ttattgatga aggtgaaaca gattggaaat taattgctat caatgcgaat gatcctgaag      660

cctcaaagtt tcatgatatt gatgatgtta agaagttcaa accgggttac ctggaagcta      720

ctcttaattg gtttagatta tataaggtac cagatggaaa accagaaaac cagtttgctt      780

ttaatggaga attcaaaaac aaggcttttg ctcttgaagt tattaaatcc actcatcaat      840

gttggaaagc attgcttatg aagaagtgta atggaggagc tataaattgc acaaacgtgc      900

agatatctga tagccctttc cgttgcactc aagaggaagc aagatcatta gttgaatcgg      960

tatcatcttc accaaataaa gaaagtaatg aagaagagca agtgtggcac ttccttggca     1020

agtgattgaa acatctgaaa ttctgctgtc aagattccca tctctaagga ctccaagtgc     1080

tagagacaag ggggtctatg agcatttact gacttcctgt taaaacttca ttttttcaaa     1140

ctttttgagc tatgcaatat ataaataaac agtaagaatt ttaaattact ctcctttgga     1200

catttattga tataaaaaga agattttggc caggcacggt ggctcatgcc tgtaatttca     1260

gcactttggg aggccgaggt gggcagatca caaggtcagg agttcaagac cagcctggcc     1320

agtatgttga aaccccatct ctattaaaaa tacaaaaatt agccaggcgt ggtggtgcat     1380

gcctgtagac ccagctactc aggaggctga ggcagaagaa ctgcttgagc ccaggaggca     1440

gaggttgcag tgagcagaga ttgtgccact gcactccagc ctaggcgaca gagagagact     1500

ccgtctcaaa aaaaaaaaaa agattttgtt tcatttcata gcacaaattt agaggcattg     1560

agttgaccat ttctagtttc tatacctgaa ggaacccatt gattttacca gtttttattt     1620

ctgtagattg gatgtaaaaa tcacagattc aataaattaa taaactttgt gtaaaaaaaa     1680

aa                                                                    1682


<210>  2609
<211>  9149
<212>  DNA
<213>  homo sapiens

<400>  2609
ccctggaggg agagagagcc agagagcggc cgagcgccta ggaggcccgc cgagcctcgc       60

cgagccccgc cagccccggc gcgagagaag ttggagagga gagcagcgca gcgcagcgag      120

tcccgtggtc gcgccccaac agcgcccgac agcccccgat agcccaaacc gcggccctag      180

ccccggccgc acccccagcc cgcgccagca tgatgaacaa cagcggctac tcagacgccg      240

gcctcggcct gggcgatgag acagacgaga tgccgtccac ggagaaggac ctggcggagg      300

acgcgccgtg gaagaagatc cagcagaaca cattcacgcg ctggtgcaat gagcacctca      360

agtgcgtggg caagcgcctg accgacctgc agcgcgacct cagcgacggg ctccggctca      420

tcgcgctgct cgaggtgctc agccagaagc gcatgtaccg caagttccat ccgcgcccca      480

acttccgcca aatgaagctg gagaacgtgt ccgtggccct cgagttcctc gagcgcgagc      540

acatcaagct cgtgtccata gacagcaagg ccatcgtgga tgggaacctg aagctgatcc      600

tgggcctgat ctggacgctg atcctgcact actccatctc catgcccatg tgggaggatg      660

aagatgatga ggatgcccgc aaacagacgc ccaagcagcg gctgcttggc tggatccaga      720

acaaggtgcc ccagctgccc atcaccaact tcaaccgtga ctggcaggac ggcaaagctc      780

tgggcgccct ggtggacaac tgcgcccccg gtctctgccc cgactgggag gcctgggacc      840

ccaaccagcc cgtggagaac gcccgggagg ccatgcagca ggccgacgac tggcttgggg      900

tgccccaggt cattgcccct gaggagattg tggaccccaa cgtggatgag cattctgtta      960

tgacctacct gtcccagttc cccaaggcca agctcaaacc tggtgcccct gttcgatcca     1020

agcagctgaa ccccaagaaa gccatcgcct atgggcctgg catcgagcca cagggcaaca     1080

ccgtgctgca gcctgcccac ttcaccgtgc agacggtgga cgcgggcgtg ggcgaggtgc     1140

tggtctacat cgaggaccct gaaggccaca ccgaggaggc taaggtggtt cccaacaatg     1200

acaaggatcg cacctatgct gtctcctatg tgcccaaggt cgctgggtta cacaaggtga     1260

ccgtgctctt tgctggccag aacattgaac gcagtccctt tgaggtgaac gtgggcatgg     1320

ccctgggaga tgccaacaag gtgtcagccc gtggccctgg cctggaacct gtgggcaatg     1380

tggccaacaa acccacctac tttgacatct acactgcggg ggccggcact ggcgatgttg     1440

ctgtggtgat cgtggaccca cagggccggc gggacacagt ggaggtggcc ctggaggaca     1500

agggtgacag cacgttccgc tgcacataca gacctgccat ggaggggcca cataccgtgc     1560

atgtggcctt tgcgggtgcc cccatcaccc gcagtccctt ccctgtccat gtgtcggaag     1620

cctgtaaccc caacgcctgc cgcgcctctg ggcgaggcct gcagcccaag ggtgttcgcg     1680

tgaaagaggt ggctgacttc aaggtgttta ccaagggtgc cggcagcggg gagctcaagg     1740

tcacggtcaa ggggccaaag ggcacagagg agccagtgaa ggtgcgggag gctggggatg     1800

gtgtgttcga gtgcgagtac tacccggtgg tgcctgggaa gtatgtggtg accatcacgt     1860

ggggcggcta cgccatccct cgcagcccct ttgaggtaca ggtgagccca gaggcaggag     1920

tgcaaaaggt ccgggcctgg ggtcctggtt tggagactgg ccaggtgggc aagtcagccg     1980

attttgtggt ggaagccatt ggcaccgagg tggggacact gggcttctcc atcgaggggc     2040

cctcacaagc caagatcgaa tgtgacgaca agggggatgg ctcctgcgat gtgcggtact     2100

ggcccacgga gcctggggag tacgctgtgc acgtcatctg tgacgatgag gacatccgag     2160

actcaccctt cattgcccac atcctgcccg ccccacctga ctgcttccca gataaggtga     2220

aggcctttgg gcctggcctg gagcctaccg gctgcatcgt ggacaagccc gctgagttca     2280

ccattgatgc tcgtgcagct ggcaagggag acctgaagct ctatgcccag gacgccgacg     2340

gctgtcccat cgacatcaag gtgatcccca acggcgacgg caccttccgc tgctcctacg     2400

tgcccaccaa gcccattaag cacaccatca tcatctcctg gggaggcgta aacgtgccca     2460

agagcccctt ccgggtgaac gtgggcgagg gcagccaccc cgagcgggta aaggtgtacg     2520

gccccggagt ggagaagaca ggcctcaagg ccaatgagcc cacctacttc acggtggact     2580

gcagcgaggc ggggcaaggc gacgtgagca tcggcatcaa gtgcgcccca ggcgtggtgg     2640

gccctgcaga ggctgacatt gacttcgaca tcatcaagaa tgacaacgac accttcaccg     2700

tcaagtacac gccaccaggg gcgggccgct acaccatcat ggtgctgttt gccaaccagg     2760

agatccccgc cagccccttc cacatcaagg tggacccatc ccacgatgcc agcaaagtca     2820

aggccgaggg ccctgggctg aatcgcacag gtgtggaagt cgggaagccc acccacttca     2880

cggtgctgac caagggagcc ggcaaggcca agctggatgt gcagtttgca gggacagcca     2940

agggcgaggt tgtgcgggac tttgagatca tagacaacca tgactactcc tacactgtca     3000

agtacaccgc tgtccagcag ggcaacatgg cagtgacagt gacttatggc ggggaccctg     3060

tccccaagag cccctttgtg gtgaatgtgg cacccccgct ggacctcagc aaaatcaaag     3120

ttcagggcct taatagcaag gtggctgtgg gacaggaaca agcattctct gtgaacacac     3180

gaggggctgg cggtcagggc caactggatg tgcggatgac ttcgccctct cgccggccca     3240

tcccctgcaa gctggagcca ggcggtggag cggaagccca ggctgtgcgc tacatgcccc     3300

cggaggaggg gccctacaag gtggatatca cctacgatgg tcacccggtg cctggcagcc     3360

cgtttgctgt ggagggtgtc ctgccccctg atccctccaa ggtctgtgct tatggcccgg     3420

gtctcaaggg tggactggta ggcacccccg cgccattctc catcgacacc aagggggctg     3480

gcacaggtgg cctggggctg accgtagagg gcccctgcga ggccaagatc gagtgccagg     3540

acaatggtga tggctcatgt gctgtcagct acctgcccac ggagcctggc gagtacacca     3600

tcaacatcct gtttgctgag gcccacatcc ctggctcgcc cttcaaagcc accattcggc     3660

ctgtgtttga cccgagcaag gtgcgggcca gtggaccggg cctggagcgc ggcaaggtcg     3720

gtgaggcagc caccttcact gtggactgct cagaggcagg cgaggcggag ctgaccattg     3780

agatcctgtc ggatgccggg gtcaaggccg aggtgctgat ccacaacaac gcggatggca     3840

cctaccacat cacctacagc cctgccttcc ctggcaccta caccattacc atcaagtatg     3900

gcgggcatcc cgtgcccaaa ttccccaccc gtgtccatgt gcagcctgcg gtcgatacca     3960

gtggcgtcaa ggtctcaggg cctggtgttg agccacacgg tgtcctgcgg gaggtgacca     4020

ctgagttcac tgtggatgca agatccctaa cagccacagg cggcaaccac gtgacggctc     4080

gtgtgctcaa cccctcgggg gccaagacag acacctatgt gacagacaat ggggacggca     4140

cctaccgagt gcagtacacc gcctacgagg agggcgtgca tctggtggag gtcctgtatg     4200

atgaggtcgc tgtgcccaag agccccttcc gagtgggcgt gaccgagggc tgtgatccca     4260

cccgcgtccg agccttcggg ccaggcctgg agggtggctt ggtcaacaag gccaaccgat     4320

tcactgtgga gaccagggga gcgggcaccg ggggccttgg cctagccatc gagggtccct     4380

cggaagccaa gatgtcctgc aaggacaaca aggatggtag ctgcaccgtg gagtacatcc     4440

ccttcactcc tggagactat gacgtcaaca tcaccttcgg ggggcggccc atcccaggga     4500

gcccgttccg cgtgccagtg aaggatgtgg tggaccctgg gaaggtgaag tgctcagggc     4560

cagggctggg ggctggtgtc agggcccggg ttcctcagac cttcacagtg gactgcagtc     4620

aagctggccg ggcgcccctg caggtggctg tgctgggccc cacaggtgtg gccgagcctg     4680

tggaggtgcg ggacaatgga gatggcaccc acactgtcca ctacacccca gccactgacg     4740

ggccctacac ggtagccgtc aagtatgctg accaggaggt gccacgcagc cccttcaaga     4800

tcaaggtcct cccagctcat gatgccagca aggtgcgggc cagcggccca ggcctcaacg     4860

cctctggcat ccctgccagc ctgcctgtgg agttcaccat cgacgcacgg gacgcgggcg     4920

aggggttgct cactgtccag atcttggacc ccgagggtaa gcccaagaag gccaacatcc     4980

gggacaatgg ggatggcacg tacactgtgt cctacctgcc ggacatgagt ggccggtaca     5040

ccatcaccat caagtatggc ggtgatgaga tcccctactc gcccttccgc atccatgctc     5100

tgcccactgg ggatgccagc aagtgcctcg tcacagtgtc cattggaggc catggcctgg     5160

gtgcctgcct gggccctcga atccagattg ggcaggagac ggtgatcacg gtggatgcca     5220

aggcagccgg tgaggggaag gtgacatgca cggtgtccac gccggatggg gcagagctcg     5280

atgtggatgt ggttgagaac catgacggta cctttgacat ctactacaca gcgcccgagc     5340

cgggcaagta cgtcatcacc atccgcttcg ggggtgagca catccccaac agccccttcc     5400

acgtgctggc gtgtgacccc ctgccgcacg aggaggagcc ctctgaagtg ccacagctgc     5460

gccagcccta cgctcctccc cggcccggcg cccgccccac acactgggcc acagaggagc     5520

cagtggtgcc tgtggagcca atggagtcca tgctgaggcc cttcaacctg gtcatcccct     5580

tcgcggtgca gaaaggggag ctcacaggag aggtgcggat gccctcgggg aagacggcac     5640

ggcccaacat caccgacaac aaggacggca ccatcacggt gaggtatgca cccactgaga     5700

aaggcctgca ccagatgggg atcaagtatg acggcaacca catccctggg agccccttac     5760

agttctatgt ggatgccatc aacagccgcc atgtcagtgc ctatgggcca ggcctgagcc     5820

atggcatggt caacaagcca gccaccttca ctattgtcac caaagatgct ggagaagggg     5880

gtctgtcact ggccgtggag ggcccatcca aggcagagat cacctgtaag gacaacaagg     5940

atggcacctg caccgtgtcc tatctgccga ctgcgcctgg agactacagc atcatcgtgc     6000

gcttcgatga caagcacatc ccggggagcc ccttcacagc caagatcaca ggtgatgact     6060

ccatgaggac ctcacagctg aatgtgggca cctccacgga cgtgtcactg aagatcaccg     6120

agagtgatct gagccagctg accgccagca tccgtgcccc ctcgggcaac gaggagccct     6180

gcctgctgaa gcgcctgccc aaccggcaca ttgggatctc cttcaccccc aaggaggtcg     6240

gggagcacgt ggtgagcgtg cgcaagagtg gcaagcatgt caccaacagc cccttcaaga     6300

tcctggtggg gccatctgag atcggggacg ccagcaaggt gcgggtctgg ggcaaggggc     6360

tttccgaggg acacacattc caggtggcag agttcatcgt ggacactcgc aatgcaggtt     6420

atgggggctt ggggctgagt attgaaggcc caagcaaggt ggacatcaac tgtgaggaca     6480

tggaggacgg gacatgcaaa gtcacctact gccccaccga gcccggcacc tacatcatca     6540

acatcaagtt tgctgacaag cacgtgcctg gaagcccctt cactgtgaag gtgaccggcg     6600

agggccgcat gaaggagagc atcacccggc ggagacaggc accttccatc gccaccatcg     6660

gcagcacctg tgacctcaac ctcaagatcc caggaaactg gttccagatg gtgtctgccc     6720

aggagcgcct gacacgcacc ttcacacgca gcagccacac ctacacccgc acggagcgca     6780

cggagatcag caagacgcgg ggcggggaga caaagcgcga ggtgcgggtg gaggagtcca     6840

cccaggtcgg cggggacccc ttccctgctg tgtttgggga cttcctgggc cgggagcgcc     6900

tgggatcctt cggcagcatc acccggcagc aggagggtga ggccagctct caggacatga     6960

ctgcacaggt gaccagccca tcgggcaagg tggaagccgc agagatcgtc gagggcgagg     7020

acagcgccta cagcgtgcgc tttgtgcccc aggaaatggg gccccatacg gtcgctgtca     7080

agtaccgtgg ccagcacgtg cccggcagcc cctttcagtt cactgtgggg ccgctgggtg     7140

aaggtggtgc ccacaaggtg cgggccggag gcacagggct ggagcgaggt gtggccggcg     7200

tgccagccga gttcagcatc tggacccggg aggctggcgc tgggggcctg tccattgctg     7260

tggagggtcc tagcaaagcg gagattgcat ttgaggatcg caaagatggc tcctgcggcg     7320

tctcctatgt cgtccaggaa ccaggtgact atgaggtctc catcaagttc aatgatgagc     7380

acatcccaga cagccccttt gtggtgcctg tggcctccct ctcggatgac gctcgccgtc     7440

tcactgtcac cagcctccag gagacggggc tcaaggtgaa ccagccagcg tcctttgccg     7500

tgcagctgaa cggtgcccgg ggcgtgattg atgcccgggt gcacacaccc tcgggggctg     7560

tggaggagtg ctacgtctct gagctggaca gtgacaagca caccatccgc ttcatccccc     7620

acgagaatgg cgtccactcc atcgatgtca agttcaacgg tgcccacatc cctggaagtc     7680

ccttcaagat ccgcgttggg gagcagagcc aggctgggga cccaggcttg gtgtcagcct     7740

acggtcctgg gctcgaggga ggcactaccg gtgtgtcatc agagttcatc gtgaacaccc     7800

tgaatgccgg ctcgggggcc ttgtctgtca ccattgatgg cccctccaag gtgcagctgg     7860

actgtcggga gtgtcctgag ggccatgtgg tcacttatac tcccatggcc cctggcaact     7920

acctcattgc catcaagtac ggtggccccc agcacatcgt gggcagcccc ttcaaggcca     7980

aggtcactgg tccgaggctg tccggaggcc acagccttca cgaaacatcc acggttctgg     8040

tggagactgt gaccaagtcc tcctcaagcc ggggctccag ctacagctcc atccccaagt     8100

tctcctcaga tgccagcaag gtggtgactc ggggccctgg gctgtcccag gccttcgtgg     8160

gccagaagaa ctccttcacc gtggactgca gcaaagcagg caccaacatg atgatggtgg     8220

gcgtgcacgg ccccaagacc ccctgtgagg aggtgtacgt gaagcacatg gggaaccggg     8280

tgtacaatgt cacctacact gtcaaggaga aaggggacta catcctcatt gtcaagtggg     8340

gtgacgaaag tgtccctgga agccccttca aagtcaaggt cccttgaatc ccaaaagtgc     8400

ctccccagcc tcagccccca cctccagcca cacacacatt acacacacac acacacacac     8460

acaaatgtgc cacacccaga cacgcacaga atcagacact acaaacacct gccttggggg     8520

tgaagtgaag gcccagcctc cccaccccac cgcgccccag gggttggagg accttgtctg     8580

tgtcaggaca gtgtccctcc ctgggaatgt gacatgaggg ccgactgggg ccaggctcag     8640

gggcagaggc tgggacacaa ggggctggcg agggctgcga ggccagggaa gccctgagtt     8700

tctggcgggg ctgagcagtg ggggagcatt gtgttgtggg tgtctgtgtg tgaggtcacc     8760

ctcaaactgc accgccggcc agataccctc ctgaccccga ggacttggtc tggtctctct     8820

ggtggctaca accccagagt tttaaggact tggaaaggaa agcacaatca gagaagaaaa     8880

cagcccccga accagcagga gtggcctggc acatggaccg gcctgagcga tgtgcactcc     8940

acccaagcca ggctcccagg gggcctgatt tctctctcac tgtctctttt tttaaaatgg     9000

ttgcacggct ctgccccatg gggggccttt tttacacact gcgaggccca gctttctagg     9060

ggacttttgc acatgtcatg cagctcagct gggagctgct taggtggaaa actccaaata     9120

aagtgcggct gtcgcagaaa aaaaaaaaa                                       9149


<210>  2610
<211>  3745
<212>  DNA
<213>  homo sapiens

<400>  2610
gcggccgccc aggctgcccc cgcccgcgcg cgcccgttgg ggggcccggg gagcggcgcc       60

cgcggccggg ccgcattgtg acgtagcggg gccgcggcag cgcctccacc gcccgcctac      120

ttcggctgag gctgttctgc tcctgccgct gcggtccgtc ggtcggtcag tcagtccctt      180

cgcgctcctg agccgccggc gcgccgggcg ccccgggaat ttataagtat ttgaccgtac      240

tcaaaatgtg caaggaagaa taatggaagc ccctgaatac cttgatttgg atgaaattga      300

ctttagtgat gacatatctt attcagtcac atcactcaag acgatcccag aactgtgccg      360

aagatgtgat acgcaaaacg aagacagatc agtttctagc tctagctgga attgtggcat      420

ctcaactctt attacaaaca cgcaaaagcc cacaggaatc gctgatgtgt acagtaagtt      480

ccgcccagtg aagcgggttt cgccactgaa acatcagcca gagactctgg agaacaatga      540

aagtgatgac caaaagaacc agaaagtggt tgagtaccag aaagggggtg agtctgacct      600

gggcccccag cctcaggagc ttggccctgg agatggagtg ggcggcccac caggtaagag      660

ctctgagccc agcacatcgc tgggtgaact ggagcactac gacctcgaca tggatgagat      720

tctggatgtg ccttatatta aatccagtca gcagcttgcc tcttttacca aggtgacttc      780

agaaaaaaga attttgggct tatgcacaac catcaatggc ctttctggca aagcctgctc      840

tacaggaagt tctgagagct catcatccaa catggcacca ttttgtgttc tttctcccgt      900

gaaaagccct cacttgagaa aagcatcagc tgtcatccac gaccagcaca agctgtccac      960

tgaagaaacc gagatctcac ctcctctggt taaatgtggc tctgcatatg agcctgaaaa     1020

ccagagtaaa gacttcctaa acaagacatt tagtgatcct catggtcgaa aagttgagaa     1080

gacaacacca gactgccagc tcagggcctt ccacctacaa tcctcagcag cagaatccaa     1140

accagaagag caggtcagtg gcctaaaccg gaccagctcc caaggcccag aagaaaggag     1200

tgagtatctg aaaaaagtga aaagcatctt gaacattgtt aaagaaggac agatctctct     1260

cctgccacac ctagctgcag acaatctaga caaaattcac gacgaaaatg gaaacaatct     1320

attacatatt gcggcgtcac agggacacgc agagtgtcta cagcacctca cttctttgat     1380

gggagaagac tgcctcaatg agcgcaacac tgagaagttg actccagcag gcctggccat     1440

taagaatggt cagttggagt gcgtacgctg gatggtgagc gaaacagaag ccattgcaga     1500

actgagttgt tctaaggatt ttccaagcct tattcattac gcaggttgct atggccagga     1560

aaagattctt ctgtggcttc ttcagtttat gcaagaacag ggcatctcgt tggatgaagt     1620

agaccaggat ggcaacagtg ccgttcacgt agcctcacag catggctacc ttggatgcat     1680

acagaccttg gttgaatatg gagcaaatgt caccatgcag aaccacgctg gggaaaagcc     1740

ctcccagagc gccgagcggc aggggcacac cctgtgctcc aggtacctgg tggtggtgga     1800

gacctgcatg tcgctggcct ctcaagtggt gaagttaacc aagcagctaa aggaacaaac     1860

agtagaacgt gtcacgctgc agaaccaact ccaacaattt ctagaagccc agaaatcaga     1920

gggcaagtca ctcccttctt cacccagttc accatcctca cctgcctcca gaaagtccca     1980

gtggaaatct ccagatgcag atgatgattc tgtagccaaa agcaagccag gagtccaaga     2040

ggggattcag gttcttggaa gcctgtcagc ctccagccgg gctagaccca aagcaaaaga     2100

tgaagattct gataaaatct tacgccagtt attgggaaag gaaatctcag aaaatgtctg     2160

cacccaggaa aaactgtcct tggaattcca ggatgctcag gcttcctcta gaaattctaa     2220

aaagatccca ctggagaaga gggaactgaa gttagccagg ctgagacagc tgatgcagag     2280

gtcactgagt gagtctgaca cagactccaa caactctgag gaccccaaga ctaccccagt     2340

gaggaaggct gaccgaccaa ggccgcagcc cattgtagaa agcgtagaga gtatggacag     2400

cgcagaaagc ctgcacctga tgattaagaa acacaccttg gcatcagggg gacgcaggtt     2460

tcctttcagc atcaaggcct ccaaatccct ggatggccac agcccatctc ccacctcaga     2520

gagcagcgaa ccagacttag aatcccagta tccaggctca gggagtattc ctccaaacca     2580

gccctctggt gaccctcagc agcccagccc tgacagtact gctgcccaga aagttgccac     2640

aagtcccaag agtgccctca agtctccatc ttccaagcgt aggacatctc agaacttaaa     2700

actgagagtt acctttgagg agcctgtggt gcagatggag cagcctagcc ttgaactgaa     2760

tggagaaaaa gacaaagata agggcaggac tctccagcgg acctccacaa gtaacgaatc     2820

gggggatcaa ctgaaaaggc cttttggagc ctttcgatct atcatggaga cactaagtgg     2880

caaccaaaac aataataata actaccaggc agccaaccag ctgaaaacct ctacattgcc     2940

cttgacctca cttgggagga agacagatgc caagggaaac cctgccagct ccgctagcaa     3000

aggaaagaat aaggcagcat aatgacatca atagaaaaat gaagaaatcc tacagcataa     3060

agcacattgc tgagccagag tcaaaagaac tcttcttgta aatcactttt taaattttct     3120

ctcactgatg ccctttggaa attattggaa atttctggac tatcctcttt ggaaagagaa     3180

ccatgaaaac aatgcctcac cagcagaaga acagaatatc aggatgcctt aaatttatag     3240

tagtagactg taaaagattc attttggggt gatatctgta tatataactt gtttttttaa     3300

aagatgccgt ttaaaagcat gattgggaaa atgtatgttt tttaagagta gattgattca     3360

ccctacccac aggacattca ccaagccact gataccattt tatatttcat caattgcatg     3420

agtatttgct aatgttgatt gaacctccct ttccccataa tgtgggcaga tttggctcag     3480

ctccttcatg agatcaggtc agtggtattg tttctgtcaa gagtgttttt tctgtcattt     3540

ctactttttg tataaaggaa ataaaacaat gttaacagcc acctataagc ttggggcacc     3600

tactttctaa caaatctgtg atgttctgat ttctaaggga ctttgcaagt attttgattg     3660

ctgatatttg atttcaggaa caaactgctc agtttagcag ttttcccata ggcgtcaaat     3720

aaaacattct atatttcatt aagta                                           3745


<210>  2611
<211>  3070
<212>  DNA
<213>  homo sapiens

<400>  2611
aaaccccgac cgccggcctg gcgcgcggct gcgcccaccg gctccgcgct gctgccgccg       60

ccaccgccac cccgccgccg ccccggcccg cgggccgccc aggctagtac ccgggccggc      120

ctgcctccgc cggccgtccg ggtgcccgcc gccgcgccgc gccccggccg ggcgtggatg      180

gagggcgccg cgcgccctgc ccgctgctcg gcgtgacgcg ggccccgcgc cccgcgccca      240

ccatgtccta cccgcagggc tacctgtacc aggcgcccgg ctcgctggcg ctctactcgt      300

gcccggccta cggcgcgtcg gctttggcgg ctccgcgcag cgaggagctg gcgcgctcgg      360

cgtcgggctc ggcgttcagc ccctacccgg gctcggcggc cttcacggcg caggcggcca      420

ccggcttcgg gagcccgctg cagtactcgg ccgacgccgc cgccgccgcc gccggcttcc      480

cgtcctacat gggcgcaccc tacgacgcgc acaccaccgg catgaccggc gccatcagct      540

accacccgta cggcagcgcg gcctacccgt accagctcaa cgaccccgcg taccgcaaga      600

acgccacgcg ggacgccacg gccactctca aggcctggct caacgagcac cgcaagaacc      660

cctaccccac caagggcgag aagatcatgc tagccatcat caccaagatg accctcaccc      720

aggtctccac ctggttcgcc aacgcgcgcc ggcgcctcaa gaaggagaac aagatgacct      780

gggccccgag aaacaaaagc gaagatgagg acgaggacga gggcgacgct accagaagca      840

aggacgagag tcccgacaag gcgcaggagg gcacggagac ctcggcagag gacgaaggga      900

tcagcctgca cgtggactcg ctcacggatc actcgtgctc ggccgagtcg gacggggaga      960

agcttccgtg ccgcgccggg gaccccctgt gcgaatcggg ctcggagtgc aaggacaagt     1020

atgacgacct ggaggacgac gaggacgacg acgaggaggg cgagcggggc ctggcgccgc     1080

ccaagcccgt gacctcgtcg ccgcttaccg gcttggaggc gccgctgctg agccccccgc     1140

ccgaggccgc gccccgcggt ggccgcaaga cgccccaggg cagccggacg tctccgggcg     1200

cgccgccccc cgccagcaag cccaagctgt ggtcgctggc cgagatcgcc acgtcggacc     1260

tcaagcagcc gagcctgggc ccgggctgcg ggccaccggg gctgcccgcg gccgccgcgc     1320

cggcctcaac cggggcaccg ccaggaggct cgccctaccc tgcctcgccg ctgctgggcc     1380

gccccctcta ctacacgtcg cccttctacg gcaactacac aaactacggg aacttgaacg     1440

cggcgctgca gggccagggt ctcctgcggt acaactctgc ggccgcggcc cccggcgagg     1500

ccctgcacac cgcgccaaag gcggccagcg acgcgggcaa ggcgggcgcg cacccgctcg     1560

agtcccacta ccggtccccg ggcggcggct acgagcccaa gaaagatgcc agcgagggct     1620

gcaccgtggt tggcgggggc gtccagccct acctatagaa gggccgagca cagcaatgca     1680

agtaagtggg caccctggtg cttcccagac cctgtggagc ctcccagcac caacttgctt     1740

aatgtgtttt tcttgcttct ggtcatgggg ttagaagaca gagcatttca atcttgtcca     1800

gcttttcttt ccttaagggg gaaactatat tttctgtttt atagattccc tctttttggc     1860

acaagttcta tcactccttt acctagggaa ggaaaaaaaa aatatatata tatatgtgtg     1920

tgtgtgtgtg tgtaatatat atatgtatat atatagtaca tgtatatata tagtacatgt     1980

gtatatatat attacacact actgttgttt tcttttgaaa caatagatta ttaaaatctg     2040

ggcatttata tgcaatttag agccattttt actatgctag acacataata gacacatgct     2100

ttgatgagct tgggctacca aaacttggag tagcaaaaac ctttatagat gatgtttgca     2160

aaataagact gaagagacac gaggcgtact agtcttttat cagccctgtc caacctcccc     2220

tccacccatg tccaagtgga caggactctg acattctccc ggggctcaca acagtatctc     2280

aaaaaatatg ttgctttgca acgagtcaga attactaatc atagatcttg aagataagaa     2340

agatttggaa ccacttcaga tcaactcgtt tttataatgg tgttgttgtg gaactgaaag     2400

attggggatg atttggtttt ttccttggtc cacaggtagg tgtcacaatt gctttgaaaa     2460

aaaaaaaaaa aaaaaagtca gcaggccatt ctctcttccc aagctcataa atttacagat     2520

acaacaaaca gatgtctaaa tccagaccac atcttgtgcc actgtaaaag agaaggatcc     2580

acacagcact gtcagcccac agactctaac aattggaaca gactattgtt ggacatatgt     2640

gaatttgttg gcatagtata gtttccccga tgtatgtgtg acttttgaaa acaatctgtt     2700

tttctcagga tatcttgaat tgatcacttc attgccacgg tatatattct ataggtgtga     2760

taggatttac tgtaaagttt atttgtaaaa gatgtacaca gtagaaataa aacgtgatgg     2820

aagaacttga gtacttcaga agtggaaaca aatttgatat ttatttttat aatgatataa     2880

agcttctagt aatttatgca agttgtattg caatggaatc taaacttttt gtaaataaat     2940

tctgcctggt ttttatttga acattgctgg ttatacaatc tttgttggtt gtttaacacg     3000

aattctttac taatttatat cttaaattgt aaataaaaac agactagtct acaataaaaa     3060

aaaaaaaaaa                                                            3070


<210>  2612
<211>  2316
<212>  DNA
<213>  homo sapiens

<400>  2612
aaaccccgac cgccggcctg gcgcgcggct gcgcccaccg gctccgcgct gctgccgccg       60

ccaccgccac cccgccgccg ccccggcccg cgggccgccc aggctagtac ccgggccggc      120

ctgcctccgc cggccgtccg ggtgcccgcc gccgcgccgc gccccggccg ggcgtggatg      180

gagggcgccg cgcgccctgc ccgctgctcg gcgtgacgcg ggccccgcgc cccgcgccca      240

ccatgtccta cccgcagggc tacctgtacc aggcgcccgg ctcgctggcg ctctactcgt      300

gcccggccta cggcgcgtcg gctttggcgg ctccgcgcag cgaggagctg gcgcgctcgg      360

cgtcgggctc ggcgttcagc ccctacccgg gctcggcggc cttcacggcg caggcggcca      420

ccggcttcgg gagcccgctg cagtactcgg ccgacgccgc cgccgccgcc gccggcttcc      480

cgtcctacat gggcgcaccc tacgacgcgc acaccaccgg catgaccggc gccatcagct      540

accacccgta cggcagcgcg gcctacccgt accagctcaa cgaccccgcg taccgcaaga      600

acgccacgcg ggacgccacg gccactctca aggcctggct caacgagcac cgcaagaacc      660

cctaccccac caagggcgag aagatcatgc tagccatcat caccaagatg accctcaccc      720

aggtctccac ctggttcgcc aacgcgcgcc ggcgcctcaa gaaggagaac aagatgacct      780

gggccccgag aaacaaaagc gaagatgagg acgaggacga gggcgacgct accagaagca      840

aggacgagag tcccgacaag gcgcaggagg gcacggagac ctcggcagag gacgaaggga      900

tcagcctgca cgtggactcg ctcacggatc actcgtgctc ggccgagtcg gacggggaga      960

agcttccgtg ccgcgccggg gaccccctgt gcgaatcggg ctcggagtgc aaggacaagt     1020

atgacgacct ggaggacgac gaggacgacg acgaggaggg cgagcggggc ctggcgccgc     1080

ccaagcccgt gacctcgtcg ccgcttaccg gcttggaggc gccgctgctg agccccccgc     1140

ccgaggccgc gccccgcggt ggccgcaaga cgccccaggg cagccggacg tctccgggcg     1200

cgccgccccc cgccagcaag cccaagctgt ggtcgctggc cgagatcgcc acgtcggacc     1260

tcaagcagcc gagcctgggc ccgggctgcg ggccaccggg gctgcccgcg gccgccgcgc     1320

cggcctcaac cggggcaccg ccaggaggct cgccctaccc tgcctcgccg ctgctgggcc     1380

gccccctcta ctacacgtcg cccttctacg gcaactacac aaactacggg aacttgaacg     1440

cggcgctgca gggccagggt ctcctgcggt acaactctgc ggccgcggcc cccggcgagg     1500

ccctgcacac cgcgccaaag gcggccagcg acgcgggcaa ggcgggcgcg cacccgctcg     1560

agtcccacta ccggtccccg ggcggcggct acgagcccaa gaaagatgcc agcgagggct     1620

gcaccgtggt tggcgggggc gtccagccct acctatagaa gggccgagca cagcaatgca     1680

agtaggtgtc acaattgctt tgaaaaaaaa aaaaaaaaaa aagtcagcag gccattctct     1740

cttcccaagc tcataaattt acagatacaa caaacagatg tctaaatcca gaccacatct     1800

tgtgccactg taaaagagaa ggatccacac agcactgtca gcccacagac tctaacaatt     1860

ggaacagact attgttggac atatgtgaat ttgttggcat agtatagttt ccccgatgta     1920

tgtgtgactt ttgaaaacaa tctgtttttc tcaggatatc ttgaattgat cacttcattg     1980

ccacggtata tattctatag gtgtgatagg atttactgta aagtttattt gtaaaagatg     2040

tacacagtag aaataaaacg tgatggaaga acttgagtac ttcagaagtg gaaacaaatt     2100

tgatatttat ttttataatg atataaagct tctagtaatt tatgcaagtt gtattgcaat     2160

ggaatctaaa ctttttgtaa ataaattctg cctggttttt atttgaacat tgctggttat     2220

acaatctttg ttggttgttt aacacgaatt ctttactaat ttatatctta aattgtaaat     2280

aaaaacagac tagtctacaa taaaaaaaaa aaaaaa                               2316


<210>  2613
<211>  2441
<212>  DNA
<213>  homo sapiens

<400>  2613
cttcccccgc ccccgcagtc tctctctctc tctctctcct tcccccaacc ctccctccct       60

cctccccccg ctccttcccc caaccctctc tctctctccc tctgtctccc tccctctctc      120

tctcccgccg cgcccgcctc ccgcccgccc tcgctccctc cactcctctc ccctcccctc      180

cccggcactg cagcaccagc cgtctgcagc tccggccgcc acttgcgcct ctccagcctc      240

cgcaggccca accgccgcca gcaccatggc cagcaccatt tccgcctaca aggagaagat      300

gaaggagctg tcggtgctgt cgctcatctg ctcctgcttc tacacacagc cgcaccccaa      360

taccgtctac cagtacgggg acatggaggt gaagcagctg gacaagcggg cctcaggcca      420

gagcttcgag gtcatcctca agtccccttc tgacctgtcc ccagagagcc ctatgctctc      480

ctccccaccc aagaagaagg acacctccct ggaggagctg caaaagcggc tggaggcagc      540

cgaggagcgg aggaagacgc aggaggcgca ggtgctgaag cagctggcgg agcggcgcga      600

gcacgagcgc gaggtgctgc acaaggcgct ggaggagaat aacaacttca gccgccaggc      660

ggaggagaag ctcaactaca agatggagct cagcaaggag atccgcgagg cacacctggc      720

cgcactgcgc gagcggctgc gcgagaagga gctgcacgcg gccgaggtgc gcaggaacaa      780

ggagcagcga gaagagatgt cgggctaagg gcccgggacg ggcggcgccc atcctgcgac      840

agaacacgtt cgggttttgg ttttgtttcg ttcacctctg tctagatgca acttttgttc      900

ctcctccccc acccccgccc ccagcttcat gcttctcttc cgcactcagc cgccctgccc      960

tgtcctcgtg gtgagtcgct gaccacggct tcccctgcag gagccgccgg gcgtgagacg     1020

cggtccctcg gtgcagacac caggccgggc gcggctgggt cccccggggg ccctgtgaga     1080

gaggtggcgg tgaccgtggt aaacccaggg cggtggcgtg ggatcacggg tccttacgct     1140

gggctgtctg gtcagcacgt gcaggtcagg gcaggtcctc tgagccggcg cccctggcca     1200

gcaggcgagg ctacagtacc tgctgtcttt ccagggggaa ggggctcccc atgagggagg     1260

ggcgacgggg gaggggggtg atggtgcctg ggagcctgcg tgtgcagccg gtgcttgttg     1320

aactggcagg cgggtgggtg ggggctgcag ctttccttaa tgtggttgca caggggtcct     1380

ctgagaccac ctggcgtgag gtggacaccc tgggccttcc tggaagcctg cagttggggg     1440

cctgccctga gtctgctggg gagtgggcat tctctgccag ggacccatga gcaggctgca     1500

tggtctagag gttgtgggca gcatggacag tcccccactc agaagtgcaa gagttccaaa     1560

gagcctctgg cccaggcccc tccccaccag ggctttgcag atgtccttga aagacccacc     1620

ctagagccct ttggagtgct ggcccctcct gtgccctctg ccctggtgga agcggcagcc     1680

acaagtcctc ctcagggagc cccaaggggg attttgtggg accgctgccc acagatccag     1740

gtgttggaag ggcagcgggt aaggttccca agccagcccc aacacccttc ccacttggca     1800

cccagagggg gctgtgggtg gaggcctgac tccaggcctc tcctgcccac accctctggg     1860

ctgagttcct tctttccctt ggacgcccag tgctggcctt ggaggacggt cagctggagg     1920

atggcggtgg gggaggctgt ctttgtacca ctgcagcatc ccccacttct ccacggaagc     1980

cccatcccaa agctgctgcc tggccccttg ctgtaaagtg tgaagggggc ggctgagttc     2040

tcttaggacc cagagccagg gccctcaact tccatcctgc gggaggcctt ggccgggcac     2100

tgccagtgtc ttccagagtc acacccaggg accacgggag gatcctgacc cctgcagggc     2160

tcaggggtca gcagggaccc actgccccat ctccctctcc ccaccaagac agccccagaa     2220

ggagcagcca gctgggatgg gaacccaagg ctgtccacat ctggcttttg tgggactcag     2280

aaagggaagc agaactgagg gctgggatat tcctcatggt ggcagcgctc atagcgaaag     2340

cctactgtaa tatgcaccca tctcatccac gtagtaaagt gaacttaaaa attcaatcaa     2400

atgaacaatt aaataaacac ctgtgtgttt aagacatggt t                         2441


<210>  2614
<211>  3430
<212>  DNA
<213>  homo sapiens

<400>  2614
agcggaccga gccgcagccg cagccgggcg gcgggcgaga ggcggcggcg gcgggcgggc       60

cgcgggcagt cagtcgggcg gcggcggcgg cggcggcggc ggcgatgcgg cggccccgct      120

gagtccgccc gctcctggcg ccgggagcca gccgcgcgag gcggcccggg ccgggcggca      180

gcatgcggag cggcgaggag ctggacggct tcgagggcga ggcctcgagc acctccatga      240

tctcgggcgc cagcagcccg taccagccca ccaccgagcc ggtgagccag cgccgcgggc      300

tggccggcct gcgctgcgac cccgactacc tgcgcggcgc gctcggccgc ctcaaggtcg      360

cccaagtgat cttggccctg attgcattca tctgcataga gaccatcatg gcatgctccc      420

cgtgtgaagg cctctacttt tttgagtttg tgagctgcag tgcgtttgtg gtgactggcg      480

tcttgctgat tatgttcagt ctcaacctgc acatgaggat cccccagatc aactggaatc      540

tgacagattt ggtcaacact ggactcagcg ctttcctttt ctttattgct tcaatcgtac      600

tggctgcttt aaaccataga gccggagcag aaattgctgc cgtgatattt ggcttcttgg      660

cgactgcggc atatgcagtg aacacattcc tggcagtgca gaaatggaga gtcagcgtcc      720

gccagcagag caccaatgac tacatccgag cccgcacgga gtccagggat gtggacagtc      780

gccctgagat ccagcgcctg gacacttttt cctactccac aaacgtaaca gtaaggaaaa      840

aatcacccac aaacctgctg agtttgaatc actggcaact tgcctagaaa agttcagatg      900

atgggtcctt gaactgtgta tctatttcat agggtaagtt tgttgtctat gtttgttttt      960

ttatgctgag gctttaattc aggtgacttg ctatctagac acctggggtg gcgtgttttc     1020

tttgggatgc ataatacaca aaggccaggg agcctttggc ttggaccccc agggagctat     1080

tgaaactttt aaagtttgag tttaggagta agaacatatc tcagaccacc ttagtcagct     1140

ttgctgatgg gatttagggc caggtcagag tttcttttca taactgcctg aaaagagaga     1200

tggtgtgaaa caagattctg ataatggttt gtgtgagatt tgatcatagt ctaaaactat     1260

cacgtctgag ttgccttagg atgacagtgc tgacacccag taggaagtat cccattttta     1320

tcaggaaagt cagtcacgcg tagggatggt gaggagacgc gtagggatgg tgaggagggg     1380

agaggaggga gacctgctgg tgcccttgca ccagggtgag gcctgactca cgctgcttcc     1440

ccccacaggc cctgctttgc ttgcctgctt tttccagaat cgattttgca agcttcaaga     1500

ttctgttccc ctcttcgcag aagtgaggaa ggcaaatact cagggtttga agggagacct     1560

ggccggcctg agggctggca gatgtgaggg caggacacct gggatggact cgtaggctga     1620

cccaggccca aagggggctg cctgttccca actctttcac tctgtaaccc attttaaaat     1680

gagtttttga atcttgcctc aaattgacct acttggataa aatcagtgct tttcctaact     1740

tgattttgtt tgacgtggtt ccctctaaga gaatggtagg aattgaaact atttgtatat     1800

gttgaaattt gtaggggttc aggaacccat ggcagaaaca ctaaactatt tatttacaag     1860

tatgactatt tttttttcaa agtaggcaat tctttgtata ttttaaggca aataatcact     1920

tcacctctgg tgccttccat gcgtcgcata agcactcttg tcaatcatgg aattggaaaa     1980

aaagatgtac atttagttaa acaagataac actatttttg tagcatgatt ttagattgtg     2040

tccttttaat attgttttca acaatggtag ttttgaggtt ttggccattt tctctttaca     2100

cttcgtatgt attttaaaga agaaaaaaaa caaaaaaaat tccctggcta ttcctctttc     2160

ctctctgctg ctgcttctcc tgcatcttgt tcctgcttat ttaaatagtc tgagagtaag     2220

agtatatttc tgtgaaataa ttataagtca gtataattgc atttggcatt ttttaaccac     2280

ttgctcagtt tggagccact gctcacctca aacagtacaa agaaagtggt tccatatttt     2340

acaaacagaa gagtagcatc agagccctga cctcctgtct ttgggtgtaa aatggtgaga     2400

ggccggtgtc cggctccttc ccctgtggtt tgggctggtg aactgagccc aagtgtattc     2460

tctggcctgg gccccttcca gaatcagtgc gagcgtcctg cagaggcatg gccttcctgc     2520

cactgcagag tgggaagctt cctgggggac ctcagccagc tccggggctc tcatcttcca     2580

ctcggatctc agattggttc gttgtggatg ctctggctag gctcggcggc cttttccagg     2640

cttcaggcct gaacaaaaca ggctgtttgc tgtgaggagc tagatgacac caagacacag     2700

acacgtactc ttcaccggct ccttttgctt ctccttcctg caggacgtga gttatgtctg     2760

gtcccaaaac ccttgagtaa actagctgag ccattgcaaa tgaaggtaca gatggattga     2820

aacataaaat tgtagctttt ggtgtccttc tgaagggtca gaatatgtaa ttatttgata     2880

accaaggaag tcaagtcaga tggctaagta gtaactttcc aatatgattt ctccgtggta     2940

cttcacctgg tggcactttt ggggggcaat gttaacaact atcacatttt actcatcaag     3000

tctctttcat ttcggcagtt taaagacaca actgtgggct ttctgaggcg atgcccgttg     3060

ggcaaactta ggtttatgtg tttggttttt cagctgacgt ggaagccctg ggtgggcgtc     3120

ccctggctgg cctggctttt gggttcaagt ctgtatgtat ggagtgggtt ggggccccaa     3180

agctttgctg ctattgattt gtccccgaca gcaggcaaag cctcacattg ccctcaattt     3240

tccccctttc atttgaagga ccagtttttc atggtacttg tcttgatctt tttcatagtg     3300

ttcaaatctg tatttttgta tgtagaggga aataattttc tcaacactaa tcgttaataa     3360

ctattgtatt aaattgtcat gaaggaactt gtttaataaa tggacgtgta aggaaaaaaa     3420

aaaaaaaaaa                                                            3430


<210>  2615
<211>  3571
<212>  DNA
<213>  homo sapiens

<400>  2615
gctggccaat caggcggctc tcgtggaggc agctagcgcg aggctgggga gcgctgagcc       60

gcgcgtcgtg ccctgcgctg cccagactag cgaacaatac agtcaggatg gctaaaggtg      120

accccaagaa accaaagggc aagatgtccg cttatgcctt ctttgtgcag acatgcagag      180

aagaacataa gaagaaaaac ccagaggtcc ctgtcaattt tgcggaattt tccaagaagt      240

gctctgagag gtggaagacg atgtccggga aagagaaatc taaatttgat gaaatggcaa      300

aggcagataa agtgcgctat gatcgggaaa tgaaggatta tggaccagct aagggaggca      360

agaagaagaa ggatcctaat gctcccaaaa ggccaccgtc tggattcttc ctgttctgtt      420

cagaattccg ccccaagatc aaatccacaa accccggcat ctctattgga gacgtggcaa      480

aaaagctggg tgagatgtgg aataatttaa atgacagtga aaagcagcct tacatcacta      540

aggcggcaaa gctgaaggag aagtatgaga aggatgttgc tgactataag tcgaaaggaa      600

agtttgatgg tgcaaagggt cctgctaaag ttgcccggaa aaaggtggaa gaggaagatg      660

aagaagagga ggaggaagaa gaggaggagg aggaggagga ggatgaataa agaaactgtt      720

tatctgtctc cttgtgaata cttagagtag gggagcgccg taattgacac atctcttatt      780

tgagaagtgt ctgttgccct cattaggttt aattacaaaa tttgatcacg atcatattgt      840

agtctctcaa agtgctctag aaattgtcag tggtttacat gaagtggcca tgggtgtctg      900

gagcaccctg aaactgtatc aaagttgtac atatttccaa acatttttaa aatgaaaagg      960

cactctcgtg ttctcctcac tctgtgcact ttgctgttgg tgtgacaagg catttaaaga     1020

tgtttctggc attttctttt tatttgtaag gtggtggtaa ctatggttat tggctagaaa     1080

tcctgagttt tcaactgtat atatctatag tttgtaaaaa gaacaaaaca accgagacaa     1140

acccttgatg ctccttgctc ggcgttgagg ctgtggggaa gatgcctttt gggagaggct     1200

gtagctcagg gcgtgcactg tgaggctgga cctgttgact ctgcaggggg catccattta     1260

gcttcaggtt gtcttgtttc tgtatatagt gacatagcat tctgctgcca tcttagctgt     1320

ggacaaaggg gggtcagctg gcatgagaat attttttttt tttaagtgcg gtagttttta     1380

aactgtttgt ttttaaacaa actatagaac tcttcattgt cagcaaagca aagagtcact     1440

gcatcaatga aagttcaaga acctcctgta cttaaacacg attcgcaacg ttctgttatt     1500

ttttttgtat gtttagaatg ctgaaatgtt tttgaagtta aataaacagt attacatttt     1560

taaaactctt ctctattata acagtcaatt tctgactcac agcagtgaac aaacccccac     1620

tccattgtat ttggagactg gcctccctat aaatgtggta gcttctttta ttactcagtg     1680

gccagctcac ttagggctga gatgaaggag agggctactt gaagctactg tgtgattttg     1740

tttgtgtctg agtggcattc agatgaagtc tggaggagtt aggagaacga cataggcaag     1800

gttcagcagc cttccaaggt ataggaaggt gggtgattag gactgaggct atctaggttt     1860

aacttttgtc ccacctccac cccctatttt gtggggccaa atgcattgct aaacagcaat     1920

ttcagagtgt atggtgtgtc aaaaattaag gccttattgt ttttctcttt cacccctacc     1980

ccccgtgctc ctggcacata tcacattatt tgtggtgccc aacatttggg gtcttgagcc     2040

tgctgctggt ctcctggatg ccagtgaggg tatgtgggat ggggtggtgg ggtaggggac     2100

ggtatccttt ttttgctcct acttggaaac accaaacacc ccaaggaaga tgataggctc     2160

catcttgggc cacctgagct atagggcagg ctaatggaat caaccatttc tgagcactaa     2220

atgtatcatg aaaagttgaa tggcctgctc ataagtttag ctcattcact ggaaatgtag     2280

attgatgttc aatgttaaac tggaaggagc ttggtttgtg tgtcagtggt tatattagtg     2340

ggtagtgtaa cattttatcc aggttggggt gaggggagat ggccacagta gcaagtggtg     2400

acactaaata ccattttgaa ggctgatgtg tatatacatc attactgtcc gtagcaatga     2460

aggatacagt actgtgttgt gggtgagtgt tgctattgcc cagcattaat atttgggtgt     2520

gtatgtttga ggctatgaaa cacgcaggag tgtttttgtg ctattaattt taagagaaag     2580

cagctttttc ttaaaattca ctgttgagaa acttgcatgt ctggaggcgg tgtcctctcc     2640

gccctgtcgg gtcctggatg agtacgagtt atggtcacgg tcacagcctg atctcttatg     2700

tgttcatagc cattcgctct cccatcagaa ctgtttgtcc tgaatgtgtt cctctagttc     2760

tagaaaatga ccactaattt aaaaaactcg gttgtgaggt ttgcccagag gcacttgttc     2820

cagaatttcc cctcctgctt cagccatgtc cttgtcactt ggcattctaa gctaaagctt     2880

tagcttccca attcgtgatg tgctaggcca agattcggga gctgttgcca gcctcgtcaa     2940

atatggaaga gaaacaacct gcggtcaaaa gggagtgatt tgttaagtgg tgcgcgtcta     3000

tctcataact agatgtacca accagggaag ggccaaggat ggaaaggggt aacttttgtg     3060

cttccaaagt agctaagcag aagtggggga gcagtttagc cagatgatct ttgattaggc     3120

aaacattgag ttttaaagag gctgtcaagt tgaggccact tggtccatta gctggggcag     3180

caagatcact actcaacgtt ttcacactgt ggcaagattg ctcttctagt ggaataatgc     3240

cctagtttct ctgagatgat gtaagtggca tgatgttacc taaggcttag gcttagcttg     3300

atttctgggc ccactgtctg tgttcttaag atgccaacct gttgcttttt tttttttttt     3360

cccccattta aaaggatagt acctactccc tctaaccacc tcaccccatt cttgaatgac     3420

attttatcct tcggaaagaa caaggctgtg atgtagtgac tattgtctgt gtctcctgtg     3480

tgtgtctgtt cttgtcacaa atgtatttgg ggacgttgga tgcattcatt ttctgtaata     3540

aagtttctta atcactcttc ccaaaaagta a                                    3571


<210>  2616
<211>  3473
<212>  DNA
<213>  homo sapiens

<400>  2616
tttatttatc gtagtgggga tcgtcccccg gcgcgagctt ccgtcgcaac ggccgggaaa       60

gaaaccagta gcgggacgga gggcgggggt ggcaagaaag tcaaggttta gaagtaagcc      120

ggagacgcct aaccctggta acatccgaat gggaacggga taggaaggaa ggcctttgag      180

agaggaggcg taaacccagg aacagtgaca gtgtaggacg aaaggcctaa gtttgttgcg      240

gaagatgggc agctctcaaa aaaggcacaa acaattgaag gatggatacc atggcatatg      300

ttaaaagcgt gttgaaagga aaataagaaa gccaggaatc tcaggatgaa tcagtctaga      360

tcgagatcag atggtggcag tgaagaaacc ttacctcaag accataatca tcatgaaaat      420

gagagaagat ggcagcaaga gcgtctccac agagaagagg cctattatca gtttattaat      480

gaactcaatg atgaagatta tcggcttatg agagaccata atcttttagg cacccctgga      540

gaaataacat cagaagaact gcaacagcgg ttagatggcg tcaaggaaca actagcatct      600

cagcctgact tgagagatgg aacgaattac agagactcag aagtccctag agaaagttca      660

catgaagatt ctcttctaga atggttgaac acctttcggc gcacaggaaa tgcaactcga      720

agtggacaaa atgggaacca aacttggaga gctgtgagtc gaacaaaccc gaacaatgga      780

gagtttcggt ttagtttgga aatccacgta aatcatgaaa atagaggatt tgaaattcat      840

ggagaagatt atacagacat tccactttca gatagtaaca gagatcatac tgcaaatagg      900

caacaaaggt caactagtcc tgtggctagg cgaacaagaa gccaaacctc agtgaatttc      960

aatggtagta gttccaacat tccaaggact aggcttgctt caagggggca aaatccagct     1020

gaaggatctt tctcaacatt gggaaggtta agaaatggaa ttgggggagc agctggcatt     1080

cctcgagcta acgcttcacg cactaatttc agtagtcaca caaaccaatc aggtggtagt     1140

gaactcaggc aaagggaggg gcaacggttt ggagcagcac atgtttggga aaatggggct     1200

agaagtaatg ttacagtgag gaatacaaac caaagattag agccaataag attacgatct     1260

acttccaata gtcgaagccg ttcaccaatt cagagacaga gtggcactgt ttatcataat     1320

tcccaaaggg aaagtagacc agtacagcaa accactagaa gatctgttag gaggagaggt     1380

agaactcgag tctttttaga gcaagataga gaacgagaac gcagaggtac tgcatatacc     1440

ccattctcta attcaaggct tgtgtcaaga ataacagtag aagaaggaga agaatccagc     1500

agatcctcaa ctgctgtacg acgacatcca acaatcacac tggaccttca agtgagaagg     1560

atccgtcctg gagaaaatag agatcgggat agtattgcaa atagaactcg atccagagta     1620

gggctagcag aaaatacagt cactattgaa agcaatagtg ggggctttcg ccgaaccatt     1680

tctcgtttag agcggtcagg tattcgaacc tatgttagta ccataacagt tcctcttcgt     1740

aggatttctg agaatgagct tgttgagcca tcatcagtgg ctcttcggtc aattttaagg     1800

cagatcatga ctgggtttgg agaactgagt tctctaatgg aggccgattc tgagtcagaa     1860

cttcaaagaa atggccagca tttaccagac atgcactcag aactgagtaa cttaggtaca     1920

gataacaaca ggagccagca cagggaaggt tcctctcaag acaggcaggc ccaaggagac     1980

agcactgaaa tgcatggtga aaacgagacc acccagcctc atactcgaaa cagtgacagt     2040

aggggtggca ggcagttgcg aaatccaaac aatttagttg aaactggaac actacccatt     2100

cttcgccttg ctcacttttt tttactaaat gaaagtgatg atgatgatcg aatacgtggt     2160

ttaaccaaag agcagattga caatctttcc accaggcact atgagcataa cagtattgat     2220

agtgaactag gtaaaatctg tagtgtttgt attagtgact atgtaactgg aaacaagctc     2280

aggcaattac cttgcatgca tgaatttcac attcattgta ttgaccgatg gctctcagag     2340

aattgcactt gtccgatctg tcggcagcct gttttagggt ctaacatagc aaacaatggg     2400

taaggtgatg ggatctactc aaatactgtt ttttagtaga actgaatgtt caagcattgt     2460

tttgctgagt tatttgtgat tagctaacca ggatgaaaaa taacagatta tatatagttt     2520

gaactatttt tcgtgtgctt ttttaaactt gttaaaaaga aatttatata aaatttaaaa     2580

tacaaatgtt aaattatcca gaaatacaga atagttaata ttgctagaac caaataacct     2640

ctaaaatgtt tttattttgg taattttgtc atgctaagca cttttgtatc tgcacaattc     2700

agtaggttaa gaatcaatct tctttttctt aatagtacag cagactttag cttcaagttt     2760

cataggctta gtacttatat ctagacattt gtgtctaaat aagcttttca ttaacttttt     2820

attttaagga cagtatcttt tcatgaaaga gtatttggct gaatgtttgc tatatatatg     2880

ttacttgaaa tgttaaattt aatatgcagc ataccatagg tgtatatata ggtatataat     2940

tttaaggtta aaatattcag tctacaagtt tggttcttat ttaagctttt gggctaatac     3000

tgcatatggc acaatgttta atattggcaa gttcatctca gagaaagggg attcagatat     3060

aattttaaag tagagataat ttactgaagc gtctctgaca atctaactta ttagacagca     3120

agcaatatat aatactgaaa aagtattcag aaatggaaaa tttacatcat ataggttatt     3180

taacttgtgt tcagcctttt tgtaactttt ttgaaagtgc aaacaattct ttggattatt     3240

aaataaggta tacagtatgc atggtttctc aaatttagtt ttaaaatcta aaagtctata     3300

aagaatcaga tgcataggca atatgttaag ttcacttgga ggctaaaaat ctccagtgaa     3360

aacaaaacga aaacctttaa gagaatgtag agtttatata aacacaaagt atgcattgaa     3420

gatctgtttc taccaataaa cattaaaaca aagactgtaa aaaaaaaaaa aaa            3473


<210>  2617
<211>  4244
<212>  DNA
<213>  homo sapiens

<400>  2617
gcgcgcgggc ggcgtagccg gcctgtctgg gccgcctcgt ggggagggag ggggcgcccg       60

gccgcccggc ggcgaccccg gggcctggcc gccaccatgg gcttcgagct ggaccgcttc      120

gacggcgacg tggacccgga cctgaagtgc gcgctgtgcc acaaggtcct ggaggacccg      180

ctgaccacgc cgtgcggcca cgtcttctgc gccggctgcg tgctgccctg ggtggtgcag      240

gagggcagct gcccggcgcg ctgccgcggt cgcctgtcgg ccaaagagct caaccacgtc      300

ctgccgctca agcgccttat cctcaagctg gacatcaagt gcgcgtacgc gacgcgcggc      360

tgcggccggg tggtcaagct gcagcagctg ccggagcacc tcgagcgctg cgacttcgcg      420

cccgcgcgct gtcgccacgc gggttgcggc caggtgctgc tgcggcgcga cgtggaggcg      480

cacatgcgcg acgcctgcga cgcgcggcca gtgggccgct gccaggaggg ctgcgggcta      540

cccttgacgc acggcgagca gcgcgcgggc ggccactgct gcgcgcgagc gctgcgggcg      600

cacaacggcg cgctccaggc ccgcctgggc gcgctgcaca aggcgctcaa gaaggaggcg      660

ctgcgcgctg ggaagcgcga gaagtcgctg gtggcccagc tggccgcggc gcagcttgag      720

ctgcagatga ccgcgctgcg ctaccagaag aaattcaccg aatacagcgc gcgcctcgac      780

tcgctcagcc gctgcgtggc cgcgccgccc ggcggcaagg gcgaagaaac caaaagtctg      840

actcttgtcc tgcatcggga ctccggctcc ctgggattca atattattgg tggccggccg      900

agtgtggata accacgatgg atcatccagt gaaggaatct ttgtatccaa gatagttgac      960

agtgggcctg cagccaagga aggaggcctg caaattcatg acaggattat tgaggtcaac     1020

ggcagagact tatccagagc aactcatgac caggctgtgg aagctttcaa gacagccaag     1080

gagcccatag tggtgcaggt gttgagaaga acaccaagga ccaaaatgtt cacgcctcca     1140

tcagagtctc agctggtgga cacgggaacc caaaccgaca tcacctttga acatatcatg     1200

gccctcacta agatgtcctc tcccagccca cccgtgctgg atccctatct cttgccagag     1260

gagcatccct cagcccatga atactacgat ccaaatgact acattggaga catccatcag     1320

gagatggaca gggaggagct ggagctggag gaagtggacc tctacagaat gaacagccag     1380

gacaagctgg gcctcactgt gtgctaccgg acggacgatg aagacgacat tgggatttat     1440

atcagtgaga ttgaccctaa cagcattgca gccaaggatg ggcgcatccg agaaggagac     1500

cgcattatcc agattaatgg gatagaggtg cagaaccgtg aagaggctgt ggctcttcta     1560

accagtgaag aaaataaaaa cttttcattg ctgattgcaa ggcctgaact ccagctggat     1620

gagggctgga tggatgatga caggaacgac tttctggatg acctgcacat ggacatgctg     1680

gaggagcagc accaccaggc catgcaattc acagctagcg tgctgcagca gaagaagcac     1740

gacgaagacg gtgggaccac agatacagcc accatcttgt ccaaccagca cgagaaggac     1800

agcggtgtgg ggcggaccga cgagagcacc cgtaatgacg agagctcgga gcaagagaac     1860

aatggcgacg acgccaccgc atcctccaac ccgctggcgg ggcagaggaa gctcacctgc     1920

agccaggaca ccttgggcag cggcgacctg cccttcagca acgagtcttt catttcggcc     1980

gactgcacgg acgccgacta cctggggatc ccggtggacg agtgcgagcg cttccgcgag     2040

ctcctggagc tcaagtgcca ggtgaagagc gccacccctt acggcctgta ctaccctagc     2100

ggccccctgg acgccggcaa gagtgaccct gagagcgtgg acaaggagct ggagctgctg     2160

aacgaagagc tgcgcagcat cgagctggag tgcctgagca tcgtgcgcgc ccacaagatg     2220

cagcagctca aggagcagta ccgcgagtcc tggatgctgc acaacagcgg cttccgcaac     2280

tacaacacca gcatcgacgt gcgcagacac gagctctcag atatcaccga gctcccggag     2340

aaatccgaca aggacagctc gagcgcctac aacacaggcg agagctgccg cagcaccccg     2400

ctcaccctgg agatctcccc cgacaactcc ttgaggagag cggcggaggg catcagctgc     2460

ccgagcagcg aaggggctgt ggggaccacg gaagcctacg ggccagcctc caagaatctg     2520

ctctccatca cggaagatcc cgaagtgggc acccctacct atagcccgtc cctgaaggag     2580

ctggacccca accagcccct ggaaagcaaa gagcggagag ccagcgacgg gagccggagc     2640

cccacgccca gccagaagct gggcagcgcc tacctgccct cctatcacca ctccccatac     2700

aagcacgcgc acatcccggc gcacgcccag cactaccaga gctacatgca gctgatccag     2760

cagaagtcgg ccgtggagta cgcgcaaagc cagatgagcc tggtgagcat gtgcaaggac     2820

ctgagctctc ccaccccgtc ggagccgcgc atggagtgga aggtgaagat ccgcagcgac     2880

gggacgcgct acatcaccaa gaggcccgtg cgggaccgcc tgctgcggga gcgcgccctg     2940

aagatccggg aagagcgcag cggcatgacc accgacgacg acgcggtgag cgagatgaag     3000

atggggcgct actggagcaa ggaggagagg aagcagcacc tggtgaaggc caaggagcag     3060

cggcggcggc gcgagttcat gatgcagagc aggttggatt gtctcaagga gcagcaagca     3120

gccgatgaca ggaaggagat gaacattctc gaactgagcc acaaaaagat gatgaagaag     3180

aggaataaga aaatcttcga taactggatg acgatccaag aactcttaac ccacggcaca     3240

aaatccccgg acggcactag agtatacaat tccttcctat cggtgactac tgtataattt     3300

tcacttctgc attatgtaca taaaggagac cactaccact ggggtagaaa ttcctgcctc     3360

gttcaatgcg gcaagttttt gtatataaga taagtacggt cttcatgttt atagtccaaa     3420

tttgcaaacc ctacaactct gggtgtcata ggtctatttt aagggaagag agagaaaaac     3480

acccttacta tcttggaagg caatattaac aaacagagct tttttcaaat agcaattgta     3540

cttttctacc tgtacccttt tacataaagt gtttaaattt cagaaagatc ttttattaag     3600

catactttca cagaataact tgtttaaact atattcatat aaaaaagtta aacacgcttt     3660

ttttcctgcc taaaacacaa atacaactgc cagtatgtat ttttaatgga accctatttt     3720

ataatggtac gttactgaat gtgtttcata tgcgtgaccg ttaagatatt atcatttagg     3780

tgaaggtttc aactcaaaac cacccaaccc ggtggttaac gatttaatac atataaccaa     3840

accggcagcg tttagagttg ggatatacat ttaaacattt tcctggttaa ggttcccaag     3900

agagtgtaaa ggttttagca gaaagcaaaa tatcttgcat ctttatggaa gtttaaagca     3960

tgtttgcaaa tattgcagcc cattgaaaga atttgcatgt acaggaaagt tgtggatgga     4020

gacggtttgt ggaattttaa gtgctcattg tagtaaactt ttgctttgta gatttgaagg     4080

tacagactta tacaggcaag ttcacaaaat catgattagt tacaaacagt aaaatgaagt     4140

taaaataaat tattattttc tatttgatat gttttgatgt gattcctcat tttgcagtgg     4200

tgcctataaa ataaaagcct tttgcagtgt ttaaaaaaaa aaaa                      4244


<210>  2618
<211>  3922
<212>  DNA
<213>  homo sapiens

<400>  2618
attctaacac acagacaggg agttagtgtg tgcggatctg tggtggagaa ggtatctcat       60

tcctctctaa catcatctcc actttgcatc tgtctctctt agtctgcttt ttttccaccg      120

atgtaacaga cctggagcca gcaggactca gaggaaagga cttaatcagg tttatgtgtc      180

ctaaaggtta tgaagacagt atggagtttc cagaccatag tagacatttg ctacagtgtc      240

tgagcgagca gagacaccag ggttttcttt gtgactgcac tgttctggtg ggagatgccc      300

agttccgagc gcaccgagct gtactggctt catgcagcat gtatttccac ctcttttaca      360

aggaccagct ggacaaaaga gacattgttc atctgaacag cgacattgtt acagcccccg      420

ctttcgctct cctgcttgaa ttcatgtatg aagggaaact ccagttcaaa gacttgccca      480

ttgaagacgt gctagcagct gccagttatc tccacatgta tgacattgtc aaagtctgca      540

aaaagaagct gaaagagaaa gccaccacgg aggcagacag caccaaaaag gaagaagatg      600

cttcaagttg ttcggacaaa gtcgagagtc tctccgatgg cagcagccac atagcaggcg      660

atttgcccag tgatgaagat gaaggagaag atgaaaaatt gaacatcctg cccagcaaaa      720

gggacttggc ggccgagcct gggaacatgt ggatgcgatt gccctcagac tcagcaggca      780

tcccccaggc tggcggagag gcagagccac acgccacagc agctggaaaa acagtagcca      840

gcccctgcag ctcaacagag tctttgtccc agaggtctgt cacctccgtg agggattcgg      900

cagatgttga ctgtgtgctg gacctgtctg tcaagtccag cctttcagga gttgaaaatc      960

tgaacagctc ttatttctct tcacaggacg tgctgagaag caacctggtg caggtgaagg     1020

tggagaaaga ggcttcctgt gatgagagtg atgttggcac taatgactat gacatggaac     1080

atagcactgt gaaagaaagt gtgagcacta ataacagggt acagtatgag ccggcccatc     1140

tggctcccct gagggaggac tcggtcttga gggagctgga ccgggaggac aaagccagtg     1200

atgatgagat gatgacccca gagagcgagc gtgtccaggt ggagggaggc atggagagca     1260

gtctgctccc ctacgtctcc aacatcctga gccccgcggg ccagatcttc atgtgccccc     1320

tgtgcaacaa ggtcttcccc agcccccaca tcctgcagat ccacctgagc acgcacttcc     1380

gcgagcagga cggcatccgc agcaagcccg ccgccgatgt caacgtgccc acgtgctcgc     1440

tgtgtgggaa gactttctct tgcatgtaca ccctcaagcg ccacgagagg actcactcgg     1500

gggagaagcc ctacacatgc acccagtgcg gcaagagctt ccagtactcg cacaacctga     1560

gccgccatgc cgtggtgcac acccgcgaga agccgcacgc ctgcaagtgg tgcgagcgca     1620

ggttcacgca gtccggggac ctgtacagac acattcgcaa gttccactgt gagttggtga     1680

actccttgtc ggtcaaaagc gaagcactga gcttgcctac tgtcagagac tggaccttag     1740

aagatagctc tcaagaactt tggaaataat tttatatata tataaataat atatatatat     1800

atacatatat ataaatagat ctctatatag ttgtggtacg gtctaaaagc agtcttgttt     1860

cctggaaata aaaagttggg atattaactt gtttttgcac tttagaatag catgagaatc     1920

tcactaattt agcattctga taaaagaaac tttagagcaa gtcagaatag agaggtgttt     1980

ttcctttgag gggatagggg aagtaagcca ataagaacct tttaaacaaa tcgtcctgtc     2040

acaaaatgct ttcatatggc ttaattttgt caacactgca ttgtcttttg agctcttttt     2100

tcccccccaa caaagttttt ttgttttttg tttttttttt taagtagaaa ttccctccag     2160

ttttattagc ctctttatat gtctcaaatt gcatgaattt tttctggctg ttggaaacct     2220

gaatgctttt agacccaaat ggaaaatttc tgaaatgctg gattatctat ttttaaacaa     2280

gcagttgact taaaactttc tgtggcaact tctggttttc tgacagttcc cagtgagaga     2340

aatgctgaaa gtacactggg atcactggga cactgtctta tgaaggtttg cttgggatga     2400

aaaaggatat tgcagcttca gcagtgttga actgtgtgtt taaaaatgtg aattactgtt     2460

attgtatact gtaattgatt acatgggctg ggggggtgtc aaagaacttg acaggttgtg     2520

ttgatgctct tagttgagtc ttgaaaagta aatattaacg ctacagaaat gcatgagttt     2580

caatatattt tttgtctttg tttgcattgt ataactttaa cgagtgagtt taaaattatt     2640

taatttcctt agaaaaatag caccatttgg aaaaaaaaac tggtgttatg aagaacgtaa     2700

atgcactgtt tttattttta ttttatataa tttaaattga ctttcccact gtctttaagt     2760

tgaaactgtt aagctgaata aaaacttaag ctgcaaattg ataacttcgc tacataacaa     2820

ggaaaatata aatgtttaca aacagcttaa agatttgcat gtgcagtgtg catttataac     2880

aaacttctaa ttgcacaaaa cccatgccag ctcagagttt aggtgtacac atttacccag     2940

ttgagcgttc ttagaataac tactgcacaa gttgacaata ggtcgttctc tctttttttt     3000

tgtttgctcc ctttttcttt ttctcccctt cctccttacc ctccctccct tactctcccc     3060

ccccaccacc accctccacc cccaactcat gaaaagattc tatggactga aaaagcccca     3120

ggctgaaagg actggactgc cttgattgac atggggaagg gggttagtag actatgtgga     3180

ttgcggcagc agaggctgca gcctaacgtg tggttttaat gaccagcacg caaggcaaaa     3240

gcattttgca cagtgtttgt tttcctgtct tgcacttaca aataaggtct atgggagtag     3300

catggaaaac gtttgctgtt tttccctttt ttttttaatt gcttttgttt aaaatttgat     3360

cgccttaact actgtaaaca tagcctattt ttgtgcttaa gatactgaat ggaaaactcc     3420

attgtgtgtt gctggactgt tttggaaata tttggttaaa tgtgtgttaa tttggctgta     3480

atggcattta aagcaaacaa acaaacaaaa aaagctgtga aaatggcctt ggagcattat     3540

ctttagttac ttgaagagtt tctagttttt ttaaaataca gtttatgtta aaataatttt     3600

tattaattta gagaagacaa tcaatgtctg tgagaaaacg gactttcttt tggattttct     3660

ttttgtggtc attgtgagtg attgcttttt ccttttctta gtttcacatt cttcctttgt     3720

tctaaaactt agactgacat ctagctttga caatcatagt atgttttatt ttcctgaggg     3780

ggaataactt ataatgctgt ttagttttgt actattggtg tgttggtgaa tttttaaact     3840

gtgtgctaac tgcaataaat tatatgaact gagaaaaaaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aa                                              3922


<210>  2619
<211>  2093
<212>  DNA
<213>  homo sapiens

<400>  2619
tcgtcaagtt tcacgctccg cccctcttcc ggacgtgacg caagggcggg gttgccggaa       60

gaagtggcga agttactttt gagggtattt gagtagcggc ggtgtgtcag gggctaaaga      120

ggaggacgaa gaaaagcaga gcaagggaac ccagggcaac aggagtagtt cactccgcga      180

gaggccgtcc acgagacccc cgcgcgcagc catgagcccc gccccccgct gttgcttgga      240

gaggggcggg acctggagag aggctgctcc gtgaccccac catgtcctct cctaccacga      300

gttccctgga tacccccctg cctggaaatg gcccccctca gcctggcgcc ccttcttctt      360

cacccactgt aaaggaggag ggtccggagc cgtggcccgg gggtccggac cctgatgtcc      420

caggcactga tgaggccagc tcagcctgca gcacagactg ggtcatccca gatcccgaag      480

aggaaccaga gcgcaagcga aagaagggcc cagccccgaa gatgctgggc cacgagcttt      540

gccgtgtctg tggggacaag gcctccggct tccactacaa cgtgctcagc tgcgaaggct      600

gcaagggctt cttccggcgc agtgtggtcc gtggtggggc caggcgctat gcctgccggg      660

gtggcggaac ctgccagatg gacgctttca tgcggcgcaa gtgccagcag tgccggctgc      720

gcaagtgcaa ggaggcaggg atgagggagc agtgcgtcct ttctgaagaa cagatccgga      780

agaagaagat tcggaaacaa cagcagcagg agtcacagtc acagtcgcag tcacctgtgg      840

ggccgcaggg cagcagcagc tcagcctctg ggcctggggc ttcccctggt ggatctgagg      900

caggcagcca gggctccggg gaaggcgagg gtgtccagct aacagcggct caagaactaa      960

tgatccagca gttggtggcg gcccaactgc agtgcaacaa acgctccttc tccgaccagc     1020

ccaaagtcac gccctggccc ctgggcgcag acccccagtc ccgagatgcc cgccagcaac     1080

gctttgccca cttcacggag ctggccatca tctcagtcca ggagatcgtg gacttcgcta     1140

agcaagtgcc tggtttcctg cagctgggcc gggaggacca gatcgccctc ctgaaggcat     1200

ccactatcga gatcatgctg ctagagacag ccaggcgcta caaccacgag acagagtgta     1260

tcaccttctt gaaggacttc acctacagca aggacgactt ccaccgtgca ggcctgcagg     1320

tggagttcat caaccccatc ttcgagttct cgcgggccat gcggcggctg ggcctggacg     1380

acgctgagta cgccctgctc atcgccatca acatcttctc ggccgaccgg cccaacgtgc     1440

aggagccggg ccgcgtggag gcgttgcagc agccctacgt ggaggcgctg ctgtcctaca     1500

cgcgcatcaa gaggccgcag gaccagctgc gcttcccgcg catgctcatg aagctggtga     1560

gcctgcgcac gctgagctct gtgcactcgg agcaggtctt cgccttgcgg ctccaggaca     1620

agaagctgcc gcctctgctg tcggagatct gggacgtcca cgagtgaggg gctggccacc     1680

cagccccaca gccttgcctg accaccctcc agcagataga cgccggcacc ccttcctctt     1740

cctagggtgg aaggggccct gggccgagcc tgtagaccta tcggctctca tcccttggga     1800

taagccccag tccaggtcca ggaggctccc tccctgccca gcgagtcttc cagaaggggt     1860

gaaagggttg caggtcccga ccactgaccc ttcccggctg ccctccctcc ccagcttaca     1920

cctcaagccc agcacgcagt gcaccttgaa cagagggagg ggaggaccca tggctctccc     1980

ccctagcccg ggagaccagg gccttcctct tcctctgctt ttatttaata aaaactaaaa     2040

acagaaacag gaaaataaaa tatgaataca atccagcccg gagctggagt gca            2093


<210>  2620
<211>  2093
<212>  DNA
<213>  homo sapiens

<400>  2620
tcgtcaagtt tcacgctccg cccctcttcc ggacgtgacg caagggcggg gttgccggaa       60

gaagtggcga agttactttt gagggtattt gagtagcggc ggtgtgtcag gggctaaaga      120

ggaggacgaa gaaaagcaga gcaagggaac ccagggcaac aggagtagtt cactccgcga      180

gaggccgtcc acgagacccc cgcgcgcagc catgagcccc gccccccgct gttgcttgga      240

gaggggcggg acctggagag aggctgctcc gtgaccccac catgtcctct cctaccacga      300

gttccctgga tacccccctg cctggaaatg gcccccctca gcctggcgcc ccttcttctt      360

cacccactgt aaaggaggag ggtccggagc cgtggcccgg gggtccggac cctgatgtcc      420

caggcactga tgaggccagc tcagcctgca gcacagactg ggtcatccca gatcccgaag      480

aggaaccaga gcgcaagcga aagaagggcc cagccccgaa gatgctgggc cacgagcttt      540

gccgtgtctg tggggacaag gcctccggct tccactacaa cgtgctcagc tgcgaaggct      600

gcaagggctt cttccggcgc agtgtggtcc gtggtggggc caggcgctat gcctgccggg      660

gtggcggaac ctgccagatg gacgctttca tgcggcgcaa gtgccagcag tgccggctgc      720

gcaagtgcaa ggaggcaggg atgagggagc agtgcgtcct ttctgaagaa cagatccgga      780

agaagaagat tcggaaacaa cagcagcagg agtcacagtc acagtcgcag tcacctgtgg      840

ggccgcaggg cagcagcagc tcagcctctg ggcctggggc ttcccctggt ggatctgagg      900

caggcagcca gggctccggg gaaggcgagg gtgtccagct aacagcggct caagaactaa      960

tgatccagca gttggtggcg gcccaactgc agtgcaacaa acgctccttc tccgaccagc     1020

ccaaagtcac gccctggccc ctgggcgcag acccccagtc ccgagatgcc cgccagcaac     1080

gctttgccca cttcacggag ctggccatca tctcagtcca ggagatcgtg gacttcgcta     1140

agcaagtgcc tggtttcctg cagctgggcc gggaggacca gatcgccctc ctgaaggcat     1200

ccactatcga gatcatgctg ctagagacag ccaggcgcta caaccacgag acagagtgta     1260

tcaccttctt gaaggacttc acctacagca aggacgactt ccaccgtgca ggcctgcagg     1320

tggagttcat caaccccatc ttcgagttct cgcgggccat gcggcggctg ggcctggacg     1380

acgctgagta cgccctgctc atcgccatca acatcttctc ggccgaccgg cccaacgtgc     1440

aggagccggg ccgcgtggag gcgttgcagc agccctacgt ggaggcgctg ctgtcctaca     1500

cgcgcatcaa gaggccgcag gaccagctgc gcttcccgcg catgctcatg aagctggtga     1560

gcctgcgcac gctgagctct gtgcactcgg agcaggtctt cgccttgcgg ctccaggaca     1620

agaagctgcc gcctctgctg tcggagatct gggacgtcca cgagtgaggg gctggccacc     1680

cagccccaca gccttgcctg accaccctcc agcagataga cgccggcacc ccttcctctt     1740

cctagggtgg aaggggccct gggccgagcc tgtagaccta tcggctctca tcccttggga     1800

taagccccag tccaggtcca ggaggctccc tccctgccca gcgagtcttc cagaaggggt     1860

gaaagggttg caggtcccga ccactgaccc ttcccggctg ccctccctcc ccagcttaca     1920

cctcaagccc agcacgcagt gcaccttgaa cagagggagg ggaggaccca tggctctccc     1980

ccctagcccg ggagaccagg gccttcctct tcctctgctt ttatttaata aaaactaaaa     2040

acagaaacag gaaaataaaa tatgaataca atccagcccg gagctggagt gca            2093


<210>  2621
<211>  3085
<212>  DNA
<213>  homo sapiens

<400>  2621
agcagtgttc tcttcgtccc cctcccccaa actgaggatt gggcaatacc acagaacctc       60

aggaaagggg ggaagagcga gcttcggccc cactaatggg ggagtgggcg gaggctggat      120

ttcccacctc ggctgcacct gggcactgga ggctgaagag gaaagtgaga atctgaagtt      180

ttgagacctc tgactggcca ggaatagctc ctggggcggg gggcaaggat gggaccatag      240

gcggaaagag tctcgcggtc ccccctgctt ctggcgcggg tccctgcgcc cggttgtgga      300

gcgtctcgcg cggggagggg gcggggggaa cggcagctcg cggtgttgtt cactcgcgcg      360

tcgagcacac ggtgggtccg gcggcgggtt ggcgccccag gcggcgttcc ctgtggcctg      420

gcgcctgggc cgctgccctg agcgggttcc gccccagagc ccgaccctcc tgggggctct      480

aggcggagtc ccgcgagccg agggggaccg gcgaccgctg ccgaagcatg aagaaggggt      540

aaggcgtgag cccccaagat ttcacgtgtt ggagaaatca gcatgttaaa acaactgttg      600

atgatagctg ttggagtaaa gttgcagtgg aagctatggc tgcaaaatcg ttaaaatctt      660

caaggtgaac tggcacaaag gttaatctca agatgccgct agtgaaaaga aacatcgatc      720

ctaggcactt gtgccacaca gcactgccta gaggcattaa gaatgaactg gaatgtgtaa      780

ccaatatttc cttggcaaat ataattagac aactaagtag cctaagtaaa tatgctgaag      840

atatatttgg agaattattc aatgaagcac atagtttttc cttcagagtc aactcattgc      900

aagaacgtgt ggaccgttta tctgttagtg ttacacagct tgatccaaag gaagaagaat      960

tgtctttgca agatataaca atgaggaaag ctttccgaag ttctacaatt caagaccagc     1020

agcttttcga tcgcaagact ttgcctattc cattacagga gacgtacgat gtttgtgaac     1080

agcctccacc tctcaatata ctcactcctt atagagatga tggtaaagaa ggtctgaagt     1140

tttataccaa tccttcgtat ttctttgatc tatggaaaga aaaaatgttg caagatacag     1200

aggataagag gaaggaaaag aggaagcaga agcagaaaaa tctagatcgt cctcatgaac     1260

cagaaaaagt gccaagagca cctcatgaca ggcggcgaga atggcagaag ctggcccaag     1320

gtccagagct ggctgaagat gatgctaatc tcttacataa gcatattgaa gttgctaatg     1380

gcccagcctc tcattttgaa acaagacctc agacatacgt ggatcatatg gatggatctt     1440

actcactttc tgccttgcca tttagtcaga tgagtgagct tctgactaga gctgaggaaa     1500

gggtattagt cagaccacat gaaccacctc cacctccacc aatgcatgga gcaggagatg     1560

caaaaccgat acccacctgt atcagttctg ctacaggttt gatagaaaat cgccctcagt     1620

caccagctac aggcagaaca cctgtgtttg tgagccccac tcccccacct cctccaccac     1680

ctcttccatc tgccttgtca acttcctcat taagagcttc aatgacttca actcctcccc     1740

ctccagtacc tcccccacct ccacctccag ccactgcttt gcaagctcca gcagtaccac     1800

cacctccagc tcctcttcag attgcccctg gagttcttca cccagctcct cctccaattg     1860

cacctcctct agtacagccc tctccaccag tagctagagc tgccccagta tgtgagactg     1920

taccagttca tccactccca caaggtgaag ttcaggggct gcctccaccc ccaccaccgc     1980

ctcctctgcc tccacctggc attcgaccat catcacctgt cacagttaca gctcttgctc     2040

atcctccctc tgggctacat ccaactccat ctactgcccc aggtccccat gttccattaa     2100

tgcctccatc tcctccatca caagttatac ctgcttctga gccaaagcgc catccatcaa     2160

ccctacctgt aatcagtgat gccaggagtg tgctactgga agcaatacga aaaggtattc     2220

agctacgcaa agtagaagag cagcgtgaac aggaagctaa gcatgaacgc attgaaaacg     2280

atgttgccac catcctgtct cgccgtattg ctgttgaata tagtgattcg gaagatgatt     2340

cagaatttga tgaagtagat tggttggagt aagaaaaatg cattgataaa tattacaaaa     2400

ctgaatgcaa atgtcctttg tggtgcttgt tccttgaaaa tgtttggtca ttctagtgtt     2460

ttgctttctt ttccttataa taaatgaccc ttttcctcca taacttttga tttctaagga     2520

aaatattagc atacatttca aactaaatgt tttacagtgg cttatctttt ttttccccct     2580

gaaaagacta atttggtcaa ataaaccact aagtattaag catggacagc tgttgttaga     2640

gtagcagatt cagttttttg atatatctta attgtgtact ttgtgaattt taatttaaag     2700

aaagcaactg aaattgaaat cttgagggca gctgtgtcta ctaatgagcc ttattccatt     2760

tcctgatgtt ttaaaagaag aaacactgcc ttgattatac gaatacactc agaaagtaca     2820

tttagcttgt agtgttgaat tctcttaaag gaatgcttga attttttcat tattgtttta     2880

ttgtttttat atacttgcct tatttgaatg tttagcagta tccccttccc acttatatat     2940

tgtgtgatat gattttgctt gcctatagga gttaaaaact tttccatgtg aaatactctg     3000

acttaaacat acatgtaact tacataactg ttaagaataa cagtctgatt taataaatgg     3060

ttcattttaa aagttaaaaa aaaaa                                           3085


<210>  2622
<211>  4322
<212>  DNA
<213>  homo sapiens

<400>  2622
aaagataagg cttgaacttt gcacttgcaa atgtcactgc atacgttttt gcactagttt       60

tttttttttt ttttctgcga ttcttttaca actaatttct tttaacaatt tgagcgcagg      120

gaagagaatg tttagggtta tgagatgcat taagtttaga acgagttgat gctcggcttt      180

tgaatgcact tgtcttcttt atttttaaag caatataaag cactcgagtg tgtgttttca      240

gcccctcctg gaatgggaaa ataagaatct ccctggatgg gagtcctctg gggcagggag      300

tgaaagcccc ggaggcagaa agggacggag aacaggggct tgcccagagc atggatagga      360

aaggagctgg ggttctccgg ggctcagcgc gcactgagaa cctgtgcccg gggctgcagc      420

tgcggacgat aaaggcgctg tctggctcat gaaggccacc tggatcaggc ttctgaaaag      480

agccaaggga ggaaggctga agaattctga tatctgtggt tcggcagact cctacactag      540

ccgtccatcc gattccgatg tatctctgga ggaggaccgg gaggcagtgc gcagagaagc      600

ggagcggcag gcccaggcac agttggaaaa agcaaagaca aagcccgttg catttgcggt      660

tcggacaaat gtcagctaca gtgcggccca tgaagatgat gttccagtgc ctggcatggc      720

catctcattc gaagcaaaag attttctgca tgttaaggaa aaatttaaca atgactggtg      780

gatagggcga ttggtaaaag aaggctgtga aatcggattc attccaagcc cagtcaaact      840

agaaaacatg aggctgcagc atgaacagag agccaagcaa gggaaattct actccagtaa      900

atcaggagga aattcatcat ccagtttggg tgacatagta cctagttcca gaaaatcaac      960

acctccatca tctgctatag acatagatgc tactggctta gatgcagaag aaaatgatat     1020

tccagcaaac caccgctccc ctaaacccag tgcaaacagt gtaacgtcac cccactccaa     1080

agagaaaaga atgcccttct ttaagaagac agagcacact cctccgtatg atgtggtacc     1140

ttccatgcga ccagtggtcc tagtgggccc ttctctgaag ggctacgagg tcacagatat     1200

gatgcaaaaa gcgctgtttg attttttaaa acacagattt gaagggcgga tatccatcac     1260

aagggtcacc gctgacatct cgcttgccaa acgctcggta ttaaacaatc ccagtaagca     1320

cgcaataata gaaagatcca acacaaggtc aagcttagcg gaagttcaga gtgaaatcga     1380

aaggattttt gaacttgcaa gaacattgca gttggtggtc cttgacgcgg atacaattaa     1440

tcatccagct caactcagta aaacctcctt ggcccctatt atagtatatg taaagatttc     1500

ttctcctaag gttttacaaa ggttaataaa atctcgaggg aaatctcaag ctaaacacct     1560

caacgtccag atggtagcag ctgataaact ggctcagtgt cctccagagc tgttcgatgt     1620

gatcttggat gagaaccagc ttgaggatgc ctgtgagcac cttgccgact atctggaggc     1680

ctactggaag gccacccatc ctcccagcag tagcctcccc aaccctctcc ttagccgtac     1740

attagccact tcaagtctgc ctcttagccc caccctagcc tctaattcac agggttctca     1800

aggtgatcag aggactgatc gctccgctcc tatccgttct gcttcccaag ctgaagaaga     1860

acctagtgtg gaaccagtca agaaatccca gcaccgctct tcctcctcag ccccacacca     1920

caaccatcgc agtgggacaa gtcgcggcct ctccaggcaa gagacatttg actcggaaac     1980

ccaggagagt cgagactctg cctacgtaga gccaaaggaa gattattccc atgaccacgt     2040

ggaccactat gcctcacacc gtgaccacaa ccacagagac gagacccacg ggagcagtga     2100

ccacagacac agggagtccc ggcaccgttc ccgggacgtg gatcgagagc aggaccacaa     2160

cgagtgcaac aagcagcgca gccgtcataa atccaaggat cgctactgtg aaaaggatgg     2220

agaagtgata tcaaaaaaac ggaatgaggc tggggagtgg aacagggatg tttacatccg     2280

ccaatgagtt ttgcccgttt gtgttttttt tttttttttt ttgaagtctt gtataactaa     2340

cagcatcccc aaaacaaagt ctttggggtc tacactgcaa tcatatgtga tctgtcttgt     2400

aatattttgt attattgctg ttgcttgaat agcaatagca tggatagagt attgagatac     2460

tttttctttt gtaagtgcta cataaattgg cctggtatgg ctgcagtcct ccggttgcat     2520

actggactct tcaaaaactg ttttgggtag ctgccacttg aacaaaatct gttgccaccc     2580

aggtgatgtt agtgttttaa gaaatgtagt tgatgtatcc aacaagccag aatcagcaca     2640

gataaaaagt ggaatttctt gtttctccag atttttaata cgttaatacg caggcatctg     2700

atttgcatat tcattcatgg accactgttt cttgcttgta cctctggctg actaaatttg     2760

gggacagatt cagtcttgcc ttacacaaag gggatcataa agttagaatc tattttctat     2820

gtactagtac tgtgtactgt atagacagtt tgtaaatgtt atttctgcaa acaaacacct     2880

tcttattata tatataatat atatatatat cagtttgatc acactatttt agagtcttaa     2940

tgccaagtca gcagatttgc tttatgaatt acagggacta gaaatgccca cattcaggaa     3000

atttgtaata acattgtcta gacacctatc ctcattctag tagaaagtgt gtacatactg     3060

taaatatgtg tgattgcttg acttgaaaag gtttgaattc tgaatgttat accatccttg     3120

taagtaagtt tgtaatttcc accataaatt atggtaaata taaaactcca gaggttgttc     3180

tactccatac agttcacact gattgtgaca cattcttagt agctagtgtc tgttctagtc     3240

actgcactgg agtctacgag ccggaactcg ctatatgcac gtgtgtgtgt ccgtatgtaa     3300

gaaagtgtgc accgagtgac tgaatggttg agatgaattg gaatgctgaa gactaacgaa     3360

gaaactagag actgatatcg agcattctgc ccacctcgct ctgtatttaa ttaattgtgc     3420

tatatgttgc tttaacaacc cattgagcag tcagggaatg tgagtaagct tgctgccaaa     3480

ggtaactagg aaagcattca tctgctgcct ccttgttttt gctcctagag agtgaaaata     3540

caggcaattt tactgtgagt gtttcactgg aaatgtacaa tctttgtgtg ttagagtatt     3600

tgttttagta agaaatgttt acacagcttg tggaattatt tcgtgggaaa ataaattttt     3660

ataacttctc ccacttcaat ttctaacctt gcctattgtt cctgttgttt gtttacctcc     3720

cagttaccta ccattcctcc ccaccaccga ctccagcagg ttcactgtct gtcagaaccc     3780

agaagtgctt cttataacca aagtttctgt tcttcagaag aaatcagggc aaaatggggt     3840

gacttgaagt gaataaaatg ttaagaatat tatcctacat aagacatgta cacagaaggg     3900

gaaccttgaa gacattatct ccatgcctca attacactgc tgtaagaagc ttacaatgtc     3960

atcatgttta aggctaagac cttttccgtg tctcaagtgt atattttgtc cagttataac     4020

tggatggtaa gacagtatta agagtgcaag tacctggcac ttgaagtttg tcccaggaaa     4080

atgcctgtgt ataattacct aacttcagat ctgcacatta acttatttaa caaaataaat     4140

cagccgggcg cagtggctca tgcctgtaat cccagcaatt tgggaggctg aggagggtgg     4200

atcacctgag gtcaggagtt caagaccagc ctggccaacg tggcgaaacc ccgtctctac     4260

taaaaagata aaaaattagc caggtgtggt ggtgcacacc tgtaatccca gctacttggg     4320

ag                                                                    4322


<210>  2623
<211>  2656
<212>  DNA
<213>  homo sapiens

<400>  2623
gaggctttaa aatctttttt catcttctag ctgtagctcg ggctgcttgt cggcttggcc       60

tccccctccc ccctttgctc tctgcctcgt ctttccccag gacttcgcta ttttgctttt      120

ttaaaaaaag gcaagaaaga actaaactcc cccctccctc tcctccagtc gggctgcacc      180

tctgccttgc actttgcaca gaggtagaga gcgcgcgagg gagagagagg aaagaaaaaa      240

aataataaag agagccaagc agaagaggag gcgagaagca tgaagtgtta actcccccgt      300

gccaaggccc gcgccgcccg gacagacgcc cgccgcgcct ccagccccga gcggacgccg      360

cgcgcgccct gcctgcagcc cgggccggcg aggcgagccc ttccttatgc aaagcgcgca      420

gcggagcggc gagcggggga cgccgcgcac cgggccgggc tcctccagct tcgccgccgc      480

agccaccacc gccgccaccg cagctcgcgg aggatcttcc cgagcctgaa gccgccggct      540

cggcgcgcaa ggaggcgagc gagcaaggag gggccggggc gagcgaggga gcacattggc      600

gtgagcaggg gggagggagg gcgggcgcgg ggggcgcggg cagggcgggg gggtgtgtgt      660

gtgagcgcgc tcggaggttt cgggccagcc accgccgcgc aagctagaag cgccccagcc      720

cggcaagctg gctcacccgc tggccaccca gcacagcccg ctggcccctc tcctgcagcc      780

catctggcgg agcggcggcg gcggcggcgg cggcggcagg agaatggcat cagaactggc      840

aatgagcaac tccgacctgc ccaccagtcc cctggccatg gaatatgtta atgacttcga      900

tctgatgaag tttgaagtga aaaaggaacc ggtggagacc gaccgcatca tcagccagtg      960

cggccgtctc atcgccgggg gctcgctgtc ctccaccccc atgagcacgc cgtgcagctc     1020

ggtgccccct tcccccagct tctcggcgcc cagcccgggc tcgggcagcg agcagaaggc     1080

gcacctggaa gactactact ggatgaccgg ctacccgcag cagctgaacc ccgaggcgct     1140

gggcttcagc cccgaggacg cggtcgaggc gctcatcagc aacagccacc agctccaggg     1200

cggcttcgat ggctacgcgc gcggggcgca gcagctggcc gcggcggccg gggccggtgc     1260

cggcgcctcc ttgggcggca gcggcgagga gatgggcccc gccgccgccg tggtgtccgc     1320

cgtgatcgcc gcggccgccg cgcagagcgg cgcgggcccg cactaccacc accaccacca     1380

ccacgccgcc ggccaccacc accacccgac ggccggcgcg cccggcgccg cgggcagcgc     1440

ggccgcctcg gccggtggcg ctgggggcgc gggcggcggt ggcccggcca gcgctggggg     1500

cggcggcggc ggcggcggcg gcggaggcgg cgggggcgcg gcgggggcgg ggggcgccct     1560

gcacccgcac cacgccgccg gcggcctgca cttcgacgac cgcttctccg acgagcagct     1620

ggtgaccatg tctgtgcgcg agctgaaccg gcagctgcgc ggggtcagca aggaggaggt     1680

gatccggctg aagcagaaga ggcggaccct gaaaaaccgc ggctatgccc agtcctgccg     1740

cttcaagagg gtgcagcaga gacacgtcct ggagtcggag aagaaccagc tgctgcagca     1800

agtcgaccac ctcaagcagg agatctccag gctggtgcgc gagagggacg cgtacaagga     1860

gaaatacgag aagttggtga gcagcggctt ccgagaaaac ggctcgagca gcgacaaccc     1920

gtcctctccc gagtttttca taactgagcc cactcgcaag ttggagccat cagtgggata     1980

cgccacattt tggaagcccc agcatcgtgt acttaccagt gtgttcacaa aatgaaattt     2040

gtgtgagagc tgtacattaa aaaaaatcat cattattatt attatttgca gtcatggaga     2100

accacctacc cctgacttct gtttagtctc ctttttaaat aaaaattact gtgttagaga     2160

agaaggctat taaatgtagt agttaactat gcctcttgtc tgggggtttc atagagaccg     2220

gtaggaaagc gcactcctgc ttttcgattt atggtgtgtg caagtaaaca ggtgcattgc     2280

tttcaacctg ccatactagt tttaaaaatt cactgaaatt acaaagatac atatatatgc     2340

atatatataa tggaaagttt cccggaatgc aacaattagc attttaaaat catatatagg     2400

catgcacatt ctaaatagta ctttttcatg cttcattgtt tctctggcag ataattttac     2460

taagaagaaa aatagatatt cgactcccct tccctaaaca aatccacggg cagaggctcc     2520

agcggagccg agccccctgg ttttctcgta ggccctagac ggtgttgcat ttatcagtga     2580

tgtcaaacgt gctcatttgt cagacatagc tgtaaatgaa aacaatgtgt ggcaaaatac     2640

aaagttaaaa aaaaaa                                                     2656


<210>  2624
<211>  4447
<212>  DNA
<213>  homo sapiens

<400>  2624
ggagacgctg ggcgcgctgt ggggcggggg cgaggttcgg gctggttgtt ccgttgcgag       60

ctgcagctgc gatctctgtg gtaggcccag aagtgtatgc tgacttgtaa agtgaagaag      120

ccagtggtgc tgcgggtgtt cttttggggt agtgtctggg atccagtacg agttgaatca      180

ttgttcaaat aaggtgtaat tgaaaagtga tcctctcttc agagatgtca aaaacaaaca      240

aatccaagtc tggatctcgc tcttctcgct caagatctgc atcaagatct cgttctcgtt      300

cattttcgaa gtctcggtcc cgaagccgat ctctctctcg ttcaaggaag cgcaggctga      360

gttctaggtc tcgttccaga tcatattctc cagctcataa cagagaaaga aaccacccaa      420

gagtatatca gaatcgggat ttccgaggtc acaacagagg ctatagaagg ccctattatt      480

tccgtgggcg taacagaggc ttttatccat ggggccaata taaccgagga ggctatggaa      540

actaccgctc aaattggcag aattaccggc aagcatacag tcctcgtcga ggccgttcaa      600

gatcccggtc cccaaagaga aggtcccctt caccaaggtc caggagccat tctagaaact      660

ctgataagtc gtcttctgac cggtcaaggc gctcctcatc ctcccgttct tcctccaacc      720

atagccgagt tgaatcttct aagcgcaagt ctgcaaagga gaaaaagtcc tcttctaagg      780

atagccggcc atctcaggct gccggggata accagggaga tgaggccaag gagcagacat      840

tctctggagg cacctctcaa gatacaaaag catctgagag ctcgaagcca tggccagatg      900

ccacctacgg cactggttct gcatcacggg cctcagcagt ttctgagctg agtcctcggg      960

agcgaagccc agctctcaaa agccccctcc agtctgtggt ggtgaggcgg cggtcacccc     1020

gtcctagccc cgtgccaaaa cctagtcctc cactttccag cacatcccag atgggctcaa     1080

ctctgccgag tggtgccggg tatcagtctg ggacacacca aggtcagttc gaccatggtt     1140

ctgggtccct gagtccatcc aaaaagagcc ctgtgggtaa gagtccacca tccactggct     1200

ccacatatgg ctcatctcag aaggaggaga gtgctgcttc aggaggagca gcctatacaa     1260

agaggtatct agaagagcag aagacagaga atggaaaaga taaggaacag aaacaaacaa     1320

ataccgataa agaaaaaata aaagagaaag ggagcttctc tgacacaggc ttgggtgatg     1380

gaaaaatgaa atctgattct tttgctccca aaactgattc tgagaagcct tttcggggca     1440

gtcagtctcc caaaaggtat aagctccgag atgactttga gaagaagatg gctgacttcc     1500

acaaggagga gatggatgat caagataagg acaaagctaa gggaagaaag gaatctgagt     1560

ttgatgatga acccaaattt atgtctaaag tcataggtgc aaacaaaaac caggaggagg     1620

agaagtcagg caaatgggag ggcctggtat atgcacctcc agggaaggaa aagcagagaa     1680

aaacagagga gctggaggag gagtctttcc cagagagatc caaaaaggaa gatcggggca     1740

agagaagcga aggtgggcac aggggctttg tgcctgagaa gaatttccga gtgactgctt     1800

ataaagcagt ccaggagaaa agctcatcac ctcccccaag aaagacctct gagagccgag     1860

acaagctggg agcgaaagga gattttccca caggaaagtc ttccttttcc attactcgag     1920

aggcacaggt caatgtccgg atggactctt ttgatgagga cctcgcacga cccagtggct     1980

tattggctca ggaacgcaag ctttgccgag atctagtcca tagcaacaaa aaggaacagg     2040

agtttcgttc cattttccag cacatacaat cagctcagtc tcagcgtagc ccctcagaac     2100

tgtttgccca acatatagtg accattgttc accatgttaa agagcatcac tttgggtcct     2160

caggaatgac attacatgaa cgctttacta aatacctaaa gagaggaact gagcaggagg     2220

cagccaaaaa caagaaaagc ccagagatac acaggagaat agacatttcc cccagtacat     2280

tcagaaaaca tggtttggct catgatgaaa tgaaaagtcc ccgggaacct ggctacaagg     2340

ctgagggaaa atacaaagat gatcctgttg atctccgcct tgatattgaa cgtcgtaaaa     2400

aacataagga gagagatctt aaacgaggta aatcgagaga atcagtggat tcccgagact     2460

ccagtcactc aagggaaagg tcagctgaaa aaacagagaa aactcataaa ggatcaaaga     2520

aacagaagaa gcatcggaga gcaagagaca ggtccagatc ctcctcctct tcctcccagt     2580

catctcactc ctacaaagca gaagagtaca ctgaagagac agaggaaaga gaggagagca     2640

ccacgggctt tgacaaatca agactgggga ccaaagactt tgtgggtcca agtgaaagag     2700

gaggtggcag agctcgagga acctttcagt ttcgagccag aggaagaggc tggggcagag     2760

gcaactactc tgggaacaat aacaacaaca gcaacaacga ttttcaaaaa agaaaccggg     2820

aagaggagtg ggacccagag tacacaccca aaagcaagaa gtattacttg catgatgacc     2880

gtgaaggcga aggcagtgac aagtgggtga gccggggccg gggccgagga gcctttcctc     2940

ggggtcgggg ccggttcatg ttccggaaat caagtaccag ccccaagtgg gcccatgaca     3000

agttcagtgg ggaggaaggg gagattgaag acgacgagag tgggacagag aaccgagaag     3060

agaaggacaa tatacagccc acaaccgagt aggggccacc cttgacggga ttcctgccca     3120

ggggagagag gcgctgggaa gatggctggt gaggagctta acagaggaac ctcaagaaga     3180

ttctgaaaat cctaccccca ccccccacca gccgcacaga ttgtactacc gcgagaggca     3240

tccctggcgc tgtctcccac tggacagagg aggctggcca tggggcccag gggtcaggcc     3300

cagcttttga gcagaataca acgcattggg ctttagctgt ttttctcatt tgttggtgtg     3360

tggggtgggg gcaggggtag ggcgggagag cgatgcttgg atttttgttt cctattagaa     3420

accaacagtt ttgttctaat ttcatttcat ttggagctaa gatgactaat ttgatgattt     3480

tcgatctctt ttcccctgtc ctgattttaa aagccccctc cttttttttt ttttttttct     3540

ttttttaggc atatgtagta atattagaaa catttaattt gggaaacttt gattcttgaa     3600

agagaaaaca aaagcatgtg aataaacttt gaagtgttca cctcagtttg ggaccaaact     3660

gcttggatct ttgtaaaaac cggttttgta tgtcaaggag gagtttaagg cctttccgac     3720

caccttgtgt tccccttttc tgcgcagcca tgtatcacgt ggagttgctc cttaccacac     3780

ctcacgtgcc cctgagccct atttcctgat ttcttctggg ctggacttcc ccgttctcca     3840

ccagcagctc cagtatccca aactttctag tcctgctgat cctcccagca acggggtgga     3900

aactggaggg cagtgtctgg tctgttttct aagaaactta tgaattctat tatctttaca     3960

aatatgagaa aattttttca atatttttta ttaatctttt tataaaatga aaagaaactc     4020

ctatgatcga ttaaggaagg tggttatggc tgggtggttc aggggttttt ttgggtttct     4080

tttttttttt ctttgtcttt ttaaccttaa gctgtttaag ttgaagcatt ctcagatgtt     4140

tggggggaaa catcctctta aaatgggtcc ttgtgcttgc cttctgggga ggcggtcctg     4200

agcaggtgaa tcataaggca tttatgcata tgttatatgc ggactgcacc cacctctccc     4260

ccccagcctt tgcctcttgc gttgttgtgc tgctttcccc ttactttgct acatttctat     4320

agttaagttg gttttacttg aatgattcat gtttaggggg aaaatgaaaa tctcccttaa     4380

aatttgtttc aactcctcct gcaaataaaa taaatgaagt ggcagatgta aaaaaaaaaa     4440

aaaaaaa                                                               4447


<210>  2625
<211>  7101
<212>  DNA
<213>  homo sapiens

<400>  2625
ccagcgtcag gccagccccg gcatgctctg cggccgcccg cggtccagct ccgacaacag       60

gaattttctc cgagagcggg ccgggctcag ttcagctgct gtccagaccc ggatcggcaa      120

cagtgccgcc tccagacgtt ctcctgccgc tcgcccgccc gtcccagcgc ccccagccct      180

cccgcgaggg cgccccggga cggaaggatc caccagtctg tcggcgcccg ccgttctcgt      240

ggtcgccgtc gccgtcgtcg tggtggtagt ctccgccgtc gcctgggcca tggccaatta      300

catccacgtc cctcccggct ccccggaggt gcccaagctg aacgtcaccg ttcaggatca      360

ggaggagcat cgctgccggg agggggccct gagcctcctg caacacctgc ggcctcactg      420

ggacccccag gaggtgaccc tgcagctctt cacagatgga atcacaaata aacttattgg      480

ctgttacgtg ggaaacacca tggaggatgt agtcctggtg agaatttatg gcaataagac      540

tgagttatta gtcgatcgag atgaggaagt aaagagtttt cgagtgttgc aggctcatgg      600

gtgtgcacca caactctact gtaccttcaa taatggacta tgctatgaat ttatacaagg      660

agaagcactg gatccaaagc atgtctgcaa cccagccatt ttcaggctaa tagctcgtca      720

gcttgctaaa atccatgcta ttcatgcaca caatggctgg atccccaaat ctaatctttg      780

gctaaagatg ggaaagtatt tctctctcat tcccacagga tttgcagatg aagacattaa      840

taaaaggttc ctaagtgata tcccaagctc tcagattctc caggaagaga tgacttggat      900

gaaggagatt ctttccaacc tgggctcacc tgttgtgctt tgccataatg acctattgtg      960

taagaatata atctacaatg agaaacaagg tgatgtacag ttcattgatt atgaatattc     1020

tggatacaac tacctggcat atgatattgg aaatcatttc aatgaatttg caggtgtgag     1080

tgatgtagac tatagtctgt atccagatag agaactacag agtcagtggc tgcgtgctta     1140

ccttgaagcc tacaaagaat ttaagggctt tgggactgaa gttactgaaa aggaggtaga     1200

aatactcttc attcaagtca atcagtttgc attggcttct catttctttt ggggattgtg     1260

ggctttgatt caagccaaat actccactat tgagtttgat ttccttgggt atgcaattgt     1320

tcgttttaac cagtacttta aaatgaagcc tgaggttact gcattaaaag tgcctgagta     1380

aagaagagat ttaattattc tccagtagct gagcaatgct tgtgaatctt ttcttaagaa     1440

atcccaaaaa gccaatatta gttaaaattc tgttgtttaa tttggttatc ttgctttata     1500

aattatgcct ctaaacaatc aaatctattt ttgaaataga ctgaatgatg tcaagaaata     1560

tacctactgc tatccgtatg tggtggatta gaaatgtgtt aaatctgcaa aaggtataaa     1620

gatgtcagtt taatttcttt gataatttaa cctatgttgt atgtgaatta tttattataa     1680

acttagcacg attctgtgac tgtttttctc tgtttcacgt tcgttgagtg taagcaatga     1740

aaatgtccca aataagtttt ttaagtttta ctttaataag attaatttca gtaaacattc     1800

tagttgttca gtgtaacctt tttatcttga tgcattgtaa gtaaaatgaa tcatttactc     1860

ttgaaatgcc agtcattgac tgatgtagat aatttaggat tttcatataa aaatagctgt     1920

ttaggaaggt gaaatacatt cactgtctct gttggtggta catcttgttg aattcaatat     1980

tagaaagtat ttctttttgg ggtaatataa cttagaatta aatccctgtt tctctatgta     2040

gtctggcagt ataaatataa atatttacca tataatcttg gaataagtat tagttaatgt     2100

taccaaaatc tgtattaaat aatgttttca aatgctaaat atggtcgtta ctattttcag     2160

ttttaaaaat tttatagtat caaattgttt ctaaccaaaa atttcctttt acttctagag     2220

atgctttatg tttttgatta ttaaatagtc actagtattg ctaatttttg aaacaaatac     2280

acaaaattta tcatatgtag aaataagaaa atattgttta ggttaattat tttttaccta     2340

tccagagtca ttccttacat ttcagtttca tgtttcattc ctcacatttt agtttcatgt     2400

tttagtttga ttctatgttt ttagactgat agcaaatgat tacttgatac atgtaagttc     2460

agcgttatat gttgaggcag ttatataatt aaataaggaa cacttagggc attgatcttg     2520

tacacttaaa atctgacaaa tgacaaaatg tgaattaagc ataaatagtc atggcaggag     2580

ggcttttgtt tatttctctt gtttttgttt aactgtattt ttaattttgt ctggtggtaa     2640

gagggaggta attattgtat ggaaagaagt tagatctttc agatagataa ataggcttca     2700

ggttttgaag tctgctctgt gtagttgagc agtcatggtt aactttactt agaaaattag     2760

tctgacaagc tttgcacttc ggtcacataa gtgcccatgt acaaagttgg cttactggat     2820

ctgcatattc aaaatatgca actacaaatt tatcctctga gaaatcttct gaggagtcta     2880

atgtattcca aatgacttaa tattctcaga caaatgcttt aaaatacttg gattatctca     2940

agatttttga agctaataaa gtaaatagaa acacaggcca ttttaaatgg taaattctag     3000

ttacataaat ataatcttaa agtatgtttg tatctgtaac agtgttagac cagatttggt     3060

ttctacctcc ccaatgttat aaatgttcac ttttgttttt ataaaccata ttactgtaag     3120

atcaatagaa ctttgcctag ttaagtgaat ggaaccaatt aaacaactag tagcttttta     3180

taatgttagt gtgaacttga aaaattgttt ttggtggaat ttttgtctgt ggttagaaca     3240

ttttcataaa acagataaag aatgtgtaat actcttaatt tttttttttt tttttttttt     3300

ttttttgctt tctgccttct aaagtgcaac agtatatatc ttgtagaact gtgggaggag     3360

agaagataat ttttctacct tactccatat tcttacttca aactattttg aatagaggtt     3420

cactgagcca ttgctgatag actgtgcata gctactagct gtcacactat tgtaggtttt     3480

ttggagagat tcatagggaa gtgaatgtaa ccaggaataa aggctctcac tttagctctg     3540

ggactatgca gtggatcttg ggaacaaaat aagatatcta atctattttc cccattctgg     3600

ctagattttg gttgttgtga tgctcctact tcctgtatag gtttttggga tcatggtgca     3660

ggctagtaat aggattcaga attgcttccc ttttatatcg accatgtaag ggattctaaa     3720

ggagggtaaa tctcaaagtg ctctgaaatc atccctctaa aatctgtcct gtggtgtgct     3780

aagatgtctg ttgccttttt atgttaagct aaggaacttg aatgccttac ctaataactc     3840

aactagtagt aagctcattt tgtaaatatg aaaatggctg taagaagtgg cattcatgta     3900

tattcaatgt tagtcaatag accatagtgg cctggatgct ttaacaagcc aaattccgca     3960

attttttttc cttttttccc cttcatactt gtatgatctc acctgaccag tgatttcttt     4020

tcctcctaac cccatgctac caccattttc tggaaatcaa agagatgtgg tagtaaatca     4080

tacagtacac acgatcatct gagatcaata tgagcacaaa actcatcaag taggtctgcc     4140

tggaatgtat ataaaaaatg taaataaaaa tttgtaaatt agtgtgaact gtatcttgca     4200

tatgagactg tgtattgttt tgcattctct tcccttttgt agaaattttt ctgtaaggaa     4260

atgattcagc ttgttggttt tagagtaaaa atagccaaca gttgtggcta cacagtgaga     4320

tcacaggaac tggaaatagg gtttgtcggc tttggttaat gtcagtactc atttatttag     4380

cctctcagtg cttaataaga cttttcttta ttttttagtt agccgttagg ttttgtgagg     4440

ttagattcct ggaagcagtg aatttataca ctgttatatt aatagagctc cgttctttga     4500

gtcatgattc caagctaaag gaaattaaaa atgtaattta ataatttcct atttttaggg     4560

ttgttaattt ttttctacaa aaaaaccttg aaattttaga tatcccaatg tgaatctaat     4620

ttccatatat acagaaatta gacaaataat aagtctttag ttcaacttaa gcatatctca     4680

aatgacttct ctaaatttaa agttgatcat gataggatca taaaagacag aaaagactta     4740

agtaatcttg taatgacaat tatttccatt tttgctgaac taaaaatatt taacttcata     4800

aatatgttac tacagcttcc agatttaaag aaaaaaagtt tcccccactc tcaattaaaa     4860

gttagaaccc tccactttta aaattataca aatatttctt ttttacatta cacagaagcc     4920

ttctgtacca ttttacgaat ttctgtcttc ataatataag tgaaaatact gtcatttcaa     4980

ttttctgctt taaattgttt ttaataagca ttccaaagtg atacagactt aagcttttaa     5040

tcaatcagtc attcagttga tagacaaagt tagcgatgct ttatgctagg aaacttgttg     5100

acagtaacct gtgcgacttt atgcagaaga caaatgctag taattattat gcacagagga     5160

aaaatcattt taagtatgtg gtaaagcagc ttcatctttc aaaattgatt tgctctggtt     5220

tttctttagt ccattagatt ccagaatgtc cttttactgg gaatttagtt atgtattaag     5280

ataacctgtt ttcagttctt tttgaaaaga agacattatt tatattgaac caccttattt     5340

taaaattttt aacttttata taccacttgt gtgattccag tgtcatgtct tgggtttgat     5400

gtcgttggac agaaaagtgt atcaattatt ttaaatgaat ttttccccat gtttgaggct     5460

tagtctgtaa atgtgttgct gtaacagaaa atacttgggt atgcattact tgaatacttg     5520

aaaactgaaa ttaataagat gtattacata atgaattaga tttctctgaa cagtttttac     5580

actgaaaatc ttcatttctg gattgcagtt tgaaatggaa tgaagacctg aattatttgg     5640

gtagaaaaaa ttatgatagt gcttataaga actgtaaact gttttaaact attttgtgtt     5700

tgacgcatca aacttcaagt tttttgtaag tttctctcct gaaattttct ttctcttcta     5760

tactttatgc acttactata ctactgatgt aataaaagag cagggttaaa aatattgtat     5820

ctgtattcat tgtgaatcct gtagcttttc tagttaacaa aaaatcgctt tctaaaatac     5880

tcttaatccc attgttttgg ttaacatctt acccatttgt tgtatttcaa atgccattaa     5940

tcattttagt acaacaccta tgtttataaa aatttgaaaa cattacatat tgtatttaaa     6000

actaattagt gaagagtaag aaaaaaacta gccaacagaa ttgtaggtga tgcattagtt     6060

aaatttcaaa actcataata aaggaacttt cagagattgg ttgaaaccca gtggtatccc     6120

tgtaaattag ctcctgtgac tggaaaagac cccaaaaagg cagtagagga gattagtgtt     6180

tacttgctgt ggttgtggtg tgctgctact taattatagg tagtgacaca ctgaaattct     6240

tatttgtcca ataatctgaa gtagtttcct atatttatct gtactaaatt gactataaat     6300

tgagtctgca aagaggaaac tttttgactg tactgtattt aggagccttt gtacagcttg     6360

gtcaaatttc catgatatga agtatttgag ttttaaaata tactgttatt aaaaggaaaa     6420

agacatggcc attattccat gtgcttaaat gataatttcc ttattcagtt tcagaagaaa     6480

aagaatgaaa ttgggtaact gtcattgcgt tagctttatg ttgaattggg aaattgtggc     6540

ataaagctta aattcgtgtt tatcaaatgt gaaccatagt agtataatgc tgctttgtat     6600

ataatgtaag tgctacaaat agtctcagca ctgaaaatgt attgatacct cttaaatgaa     6660

tgcaactttt gatgtaggtg ttttgctatg cctcagaaaa tatctgtctg agaatttgtt     6720

aatctgtttg ataatgaaga tacttcctgt tttcttgttt catattttca tgttcaaaat     6780

ttaagtttta catttttact actgttaatt taaataaaat ttgttctgtg gataaaatga     6840

ggttggcagt gaagaaaatt aaaaacagcc tcattcatgt aactggttaa gtaaaaatac     6900

attttcacta tgtgttcata aacttttaat gaagctgttt gtctttcagt tcaaatataa     6960

gtgatgttta ggctttattt ctgttaataa ggctttttac cattgattaa atgaaggaat     7020

gtatcttttt gaagagattt atattctgta aataaaaatt cgttgtaaca ataaagttga     7080

gttctaacta cagtgtattc a                                               7101


<210>  2626
<211>  3020
<212>  DNA
<213>  homo sapiens

<400>  2626
cacgcccctg ggcggtgcgc gcgggcggtg ggtaggccgg gcaggctcac gtgatgcggg       60

ccccgcggcc cgccatataa acccgcgcgc ccgccaggcg ctgcggccgt cccgggccgt      120

gactcctcct ttcccccgcc ccgcctccgt tcggagagcc ggcgggcggg cgcctctcgg      180

ccaggaagcg cctcttggac gcgtgtgacc gatgcccaga ttgcacgacc acttctggag      240

ctgctcctgt gcgcacagcg cgaggcgccg aggccccccg cgagccagcg ccgcggggct      300

ggcggccaag gttggggaga tgatcaacgt ttccgtgtcc gggccctccc tgctggcggc      360

ccacggtgcc ccggacgctg accccgcgcc caggggccgc agtgctgcga tgagcggccc      420

cgagcccggc agcccctacc ccaacacctg gcatcatcgc ctgttgcaga ggagcctcgt      480

gctcttctcg gttggggtgg tcctagccct ggtgctcaac ctgctgcaga tccagaggaa      540

tgtcactctc ttccccgagg aggtgatcgc caccatcttt tcctccgcct ggtgggtccc      600

tccctgctgc gggacagcag ctgctgttgt tggcctactg tacccctgta tcgacagtca      660

cctcggagaa ccccacaaat ttaagagaga atgggccagt gtcatgcgct gcatagcagt      720

ttttgttggc attaaccacg ccagtgctaa attggatttt gccaataatg tccagctgtc      780

cttgacttta gcagccctat ctttgggcct ttggtggaca tttgatcgtt ccagaagtgg      840

ccttgggctg gggatcacca tagcttttct agctacgctg atcacgcagt ttctcgtgta      900

taatggtgtc tatcagtata catccccaga tttcctctat attcgttctt ggctcccttg      960

tatatttttc tcaggaggcg tcacggtggg gaacatagga cgacagttag ctatgggtgt     1020

tcctgaaaag ccccatagtg attgagtctt caaaaccacc gattctgaga gcaaggaaga     1080

ttttggaaga aaatctgact gtggattatg acaaagatta tcttttttct taagtaatct     1140

atttagatcg ggctgactgt acaaatgact cctggaaaaa actcttcacc tagtctagaa     1200

tagggaggtg gagaatgatg acttaccctg aagtcttccc ttgactgccc gcactggcgc     1260

ctgtctgtgc cctggagcat tctgcccagg ctacgtgggt tcaggcaggt ggcagcttcc     1320

caagtattcg atttcattca tgtgattaaa acaagttgcc atatttcaaa gccttgaact     1380

aagactcaat taccaacccg cagttttgtg tcagtgccca aaggaggtag gttgatggtg     1440

cttaacaaac atgaagtatg gtgtaatagg aataatattt atccaaaaga tttttaaaaa     1500

tagggctgtg tttaaaaaaa aaaacaaaac aagaaaagca gcagtgatta tagagaggtc     1560

acactctaag tggggtcgcg gcgtggccac gcttcacggt cacgctcgtc cgtcctgcag     1620

tggcgtgttt acatggtcac acgtgtgtgt atcaccagtg ggtcaactgc ttgtcattcc     1680

tcccgtggca gtttgtgtag acaatcttac tgagcaaaag gcaatgaaaa gtcttggttc     1740

ccacactgcg atatattgga attttcacct cagtttatga agtttatttc gaaatccata     1800

gtcatctaag aatgaatacc tgtctgccat gtatttcaat cttagtgagc caaaattgtt     1860

tgtttgttac tacagaatag agatgactgt tttttgccac agccctatgg aatttgcaat     1920

ctgtgattgc cttgtaaaaa ggagagtgca tatggcactg cattaaacgt gtggtgtttc     1980

tagtcaatga tattggtgag cacaatgtat tcatttaatg gcatagacca taccagacct     2040

aatttgcaag tattgggtct taaacttcaa gtgcaatgta tatgaaaacc aatctgagcc     2100

ttgtatctct taaatattta ttttttttaa cgtgtgagat gttcgagaga aggttctcca     2160

ttcatttcag tgctgcctgg aggaaactcg gcaatgattt ctttcagttg tgaagttcct     2220

ttcgtgttac accctccact gaaccctcaa ccttcgaaat actccagttt tgtgggtttg     2280

gtcattttta cttataaatt tacctttttg tattttgcaa tttacatgtg tttggtttgt     2340

tttaaattct gtgaaagtgg cttgattaaa agactccttt taaatggaag ccaccagtca     2400

gcagaatgga agcttagagg aacttgcctg tgagcgctgg tctttgtgtt tggttttgtg     2460

atgtaacgat ctttgctggg gttttttgct ttgttttgag ggaaatgtct tggagtaaat     2520

tttaagttcc tggagttaat ttgttttaca ggaattttgt tttttaaaaa aataggatca     2580

ttctgaactt tggaatgacc cccttatata ttttctgaaa atgaaaacag ttacatgaaa     2640

aaaatttcca atgaagatgt cagcatttta tgaaaaacca gaagttatta gatgaaagca     2700

gcgagtgaat ctttaaaaca gacttgatca cgcacacaca ataagtcttt ctctccgaaa     2760

ccggaagtaa atctatatct gttagaaata atgtagccaa aagaatgtaa atttgaggat     2820

ttttttgcca atagtttata gaaaatatat gaaccaaagt gatttgagtt tgtaaaaatg     2880

taaaatagta tgaacaaaat ttgcactcta ccagatttga acatctagtg aggttcacat     2940

tcatactaag ttttcaacat tgtgttcttt ttgcattcat tttttacttt tattaaaggt     3000

tcaaaaccaa aaaaaaaaaa                                                 3020


<210>  2627
<211>  2635
<212>  DNA
<213>  homo sapiens

<400>  2627
cacgcccctg ggcggtgcgc gcgggcggtg ggtaggccgg gcaggctcac gtgatgcggg       60

ccccgcggcc cgccatataa acccgcgcgc ccgccaggcg ctgcggccgt cccgggccgt      120

gactcctcct ttcccccgcc ccgcctccgt tcggagagcc ggcgggcggg cgcctctcgg      180

ccaggaagcg cctcttggac gcgtgtgacc gatgcccaga ttgcacgacc acttctggag      240

ctgctcctgt gcgcacagcg cgaggcgccg aggccccccg cgagccagcg ccaaattgga      300

ttttgccaat aatgtccagc tgtccttgac tttagcagcc ctatctttgg gcctttggtg      360

gacatttgat cgttccagaa gtggccttgg gctggggatc accatagctt ttctagctac      420

gctgatcacg cagtttctcg tgtataatgg tgtctatcag tatacatccc cagatttcct      480

ctatattcgt tcttggctcc cttgtatatt tttctcagga ggcgtcacgg tggggaacat      540

aggacgacag ttagctatgc tgataccctt ctgtgaggag ttgaatttga agaccacttg      600

gctgtttcac aaaaccagaa gtaattacag ggtgttcctg aaaagcccca tagtgattga      660

gtcttcaaaa ccaccgattc tgagagcaag gaagattttg gaagaaaatc tgactgtgga      720

ttatgacaaa gattatcttt tttcttaagt aatctattta gatcgggctg actgtacaaa      780

tgactcctgg aaaaaactct tcacctagtc tagaataggg aggtggagaa tgatgactta      840

ccctgaagtc ttcccttgac tgcccgcact ggcgcctgtc tgtgccctgg agcattctgc      900

ccaggctacg tgggttcagg caggtggcag cttcccaagt attcgatttc attcatgtga      960

ttaaaacaag ttgccatatt tcaaagcctt gaactaagac tcaattacca acccgcagtt     1020

ttgtgtcagt gcccaaagga ggtaggttga tggtgcttaa caaacatgaa gtatggtgta     1080

ataggaataa tatttatcca aaagattttt aaaaataggg ctgtgtttaa aaaaaaaaac     1140

aaaacaagaa aagcagcagt gattatagag aggtcacact ctaagtgggg tcgcggcgtg     1200

gccacgcttc acggtcacgc tcgtccgtcc tgcagtggcg tgtttacatg gtcacacgtg     1260

tgtgtatcac cagtgggtca actgcttgtc attcctcccg tggcagtttg tgtagacaat     1320

cttactgagc aaaaggcaat gaaaagtctt ggttcccaca ctgcgatata ttggaatttt     1380

cacctcagtt tatgaagttt atttcgaaat ccatagtcat ctaagaatga atacctgtct     1440

gccatgtatt tcaatcttag tgagccaaaa ttgtttgttt gttactacag aatagagatg     1500

actgtttttt gccacagccc tatggaattt gcaatctgtg attgccttgt aaaaaggaga     1560

gtgcatatgg cactgcatta aacgtgtggt gtttctagtc aatgatattg gtgagcacaa     1620

tgtattcatt taatggcata gaccatacca gacctaattt gcaagtattg ggtcttaaac     1680

ttcaagtgca atgtatatga aaaccaatct gagccttgta tctcttaaat atttattttt     1740

tttaacgtgt gagatgttcg agagaaggtt ctccattcat ttcagtgctg cctggaggaa     1800

actcggcaat gatttctttc agttgtgaag ttcctttcgt gttacaccct ccactgaacc     1860

ctcaaccttc gaaatactcc agttttgtgg gtttggtcat ttttacttat aaatttacct     1920

ttttgtattt tgcaatttac atgtgtttgg tttgttttaa attctgtgaa agtggcttga     1980

ttaaaagact ccttttaaat ggaagccacc agtcagcaga atggaagctt agaggaactt     2040

gcctgtgagc gctggtcttt gtgtttggtt ttgtgatgta acgatctttg ctggggtttt     2100

ttgctttgtt ttgagggaaa tgtcttggag taaattttaa gttcctggag ttaatttgtt     2160

ttacaggaat tttgtttttt aaaaaaatag gatcattctg aactttggaa tgaccccctt     2220

atatattttc tgaaaatgaa aacagttaca tgaaaaaaat ttccaatgaa gatgtcagca     2280

ttttatgaaa aaccagaagt tattagatga aagcagcgag tgaatcttta aaacagactt     2340

gatcacgcac acacaataag tctttctctc cgaaaccgga agtaaatcta tatctgttag     2400

aaataatgta gccaaaagaa tgtaaatttg aggatttttt tgccaatagt ttatagaaaa     2460

tatatgaacc aaagtgattt gagtttgtaa aaatgtaaaa tagtatgaac aaaatttgca     2520

ctctaccaga tttgaacatc tagtgaggtt cacattcata ctaagttttc aacattgtgt     2580

tctttttgca ttcatttttt acttttatta aaggttcaaa accaaaaaaa aaaaa          2635


<210>  2628
<211>  5533
<212>  DNA
<213>  homo sapiens

<400>  2628
gattgccatc tgacaagatc tccaaatcaa agtgataaat cgctccaaac tttttttggc       60

ggcgctgaga tgttggaggg gcgtctagcg cgcatgtgcg aaggtgtcca aactgacaat      120

gctggagaga tagcgagtgt ggattgagag aaagggagag agggagggag agagagtgaa      180

agaagaaaat acagagagtg agtgtgtgga agagagagag aaacaggaga gaaacaggag      240

ggagggagag agagagagag agagagagag agagagagag agagagagag agagagagag      300

acaggagaga gagggaggga gcgagaggga gagcaaaaga aggaaaggat ccaagaaaaa      360

aaagccccaa ccacacacca gcggctgcag gactgggcac agcatgagat ccaaaggcag      420

ggcaaggaaa ctggccacaa ataatgagtg tgtatatggc aactaccctg aaataccttt      480

ggaagaaatg ccagatgcag atggagtagc cagcactccc tccctcaata ttcaagagcc      540

atgctctcct gccacatcca gtgaagcatt cactccaaag gagggttctc cttacaaagc      600

ccccatctac atccctgatg atatccccat tcctgctgag tttgaacttc gagagtcaaa      660

tatgcctggg gcaggactag gaatatggac caaaaggaag atcgaagtag gtgaaaagtt      720

tgggccttat gtgggagagc agaggtcaaa cctgaaagac cccagttatg gatgggagat      780

cttagacgaa ttttacaatg tgaagttctg catagatgcc agtcaaccag atgttggaag      840

ctggctcaag tacattagat tcgctggctg ttatgatcag cacaaccttg ttgcatgcca      900

gataaatgat cagatattct atagagtagt tgcagacatt gcgccgggag aggagcttct      960

gctgttcatg aagagcgaag actatcccca tgaaactatg gcgccggata tccacgaaga     1020

acggcaatat cgctgcgaag actgtgacca gctctttgaa tctaaggctg aactagcaga     1080

tcaccaaaag tttccatgca gtactcctca ctcagcattt tcaatggttg aagaggactt     1140

tcagcaaaaa ctcgaaagcg agaatgatct ccaagagata cacacgatcc aggagtgtaa     1200

ggaatgtgac caagtttttc ctgatttgca aagcctggag aaacacatgc tgtcacatac     1260

tgaagagagg gaatacaagt gtgatcagtg tcccaaggca tttaactgga agtccaattt     1320

aattcgccac cagatgtcac atgacagtgg aaagcactat gaatgtgaaa actgtgccaa     1380

ggttttcacg gaccctagca accttcagcg gcacattcgc tctcagcatg tcggtgcccg     1440

ggcccatgca tgcccggagt gtggcaaaac gtttgccact tcgtcgggcc tcaaacaaca     1500

caagcacatc cacagcagtg tgaagccctt tatctgtgag gtctgccata aatcctatac     1560

tcagttttca aacctttgcc gtcataagcg catgcatgct gattgcagaa cccaaatcaa     1620

gtgcaaagac tgtggacaaa tgttcagcac tacgtcttcc ttaaataaac acaggaggtt     1680

ttgtgagggc aagaaccatt ttgcggcagg tggatttttt ggccaaggca tttcacttcc     1740

tggaacccca gctatggata aaacgtccat ggttaatatg agtcatgcca acccgggcct     1800

tgctgactat tttggcgcca ataggcatcc tgctggtctt acctttccaa cagctcctgg     1860

attttctttt agcttccctg gtctgtttcc ttccggcttg taccacaggc ctcctttgat     1920

acctgctagt tctcctgtta aaggactatc aagtactgaa cagacaaaca aaagtcaaag     1980

tcccctcatg acacatcctc agatactgcc agctacacag gatattttga aggcactatc     2040

taaacaccca tctgtagggg acaataagcc agtggagctc cagcccgaga ggtcctctga     2100

agagaggccc tttgagaaaa tcagtgacca gtcagagagt agtgaccttg atgatgtcag     2160

tacaccaagt ggcagtgacc tggaaacaac ctcgggctct gatctggaaa gtgacattga     2220

aagtgataaa gagaaattta aagaaaatgg taaaatgttc aaagacaaag taagccctct     2280

tcagaatctg gcttcaataa ataataagaa agaatacagc aatcattcca ttttctcacc     2340

atctttagag gagcagactg cggtgtcagg agctgtgaat gattctataa aggctattgc     2400

ttctattgct gaaaaatact ttggttcaac aggactggtg gggctgcaag acaaaaaagt     2460

tggagcttta ccttaccctt ccatgtttcc cctcccattt tttccagcat tctctcaatc     2520

aatgtaccca tttcctgata gagacttgag atcgttacct ttgaaaatgg aaccccaatc     2580

accaggtgaa gtaaagaaac tgcagaaggg cagctctgag tccccctttg atctcaccac     2640

taagcgaaag gatgagaagc ccttgactcc agtcccctcc aagcctccag tgacacctgc     2700

cacaagccaa gaccagcccc tggatctaag tatgggcagt aggagtagag ccagtgggac     2760

aaagctgact gagcctcgaa aaaaccacgt gtttggggga aaaaaaggaa gcaacgtcga     2820

atcaagacct gcttcagatg gttccttgca gcatgcaaga cccactcctt tctttatgga     2880

ccctatttac agagtagaga aaagaaaact aactgaccca cttgaagctt taaaagagaa     2940

atacttgagg ccttctccag gattcttgtt tcacccacaa ttccaactgc ctgatcagag     3000

aacttggatg tcagctattg aaaacatggc agaaaagcta gagagcttca gtgccctgaa     3060

acctgaggcc agtgagctct tacagtcagt gccctctatg ttcaacttca gggcgcctcc     3120

caatgccctg ccagagaacc ttctgcggaa gggaaaggag cgctatacct gcagatactg     3180

tggcaagatt tttccaaggt ctgcaaacct aacacggcac ttgagaaccc acacaggaga     3240

gcagccttac agatgcaaat actgtgacag atcatttagc atatcttcta acttgcaaag     3300

gcatgttcgc aacatccaca ataaagagaa gccatttaag tgtcacttat gtgataggtg     3360

ttttggtcaa caaaccaatt tagacagaca cctaaagaaa catgagaatg ggaacatgtc     3420

cggtacagca acatcgtcgc ctcattctga actggaaagt acaggtgcga ttctggatga     3480

caaagaagat gcttacttca cagaaattcg aaatttcatt gggaacagca accatggcag     3540

ccaatctccc aggaatgtgg aggagagaat gaatggcagt cattttaaag atgaaaaggc     3600

tttggtgacc agtcaaaatt cagacttgct ggatgatgaa gaagttgaag atgaggtgtt     3660

gttagatgag gaggatgaag acaatgatat tactggaaaa acaggaaagg aaccagtgac     3720

aagtaattta catgaaggaa accctgagga tgactatgaa gaaaccagtg ccctggagat     3780

gagttgcaag acatccccag tgaggtataa agaggaagaa tataaaagtg gactttctgc     3840

tctagatcat ataaggcact tcacagatag cctcaaaatg aggaaaatgg aagataatca     3900

atattctgaa gctgagctgt cttcttttag tacttcccat gtgccagagg aacttaagca     3960

gccgttacac agaaagtcca aatcgcaggc atatgctatg atgctgtcac tgtctgacaa     4020

ggagtccctc cattctacat cccacagttc ttccaacgtg tggcacagta tggccagggc     4080

tgcggcggaa tccagtgcta tccagtccat aagccacgta tgacgttatc aaggttgacc     4140

agagtgggac caagtccaac agtagcatgg ctctttcata taggactatt tacaagactg     4200

ctgagcagaa tgccttataa acctgcaggg tcactcatct aaagtctagt gaccttaaac     4260

tgaatgattt aaaaaagaaa agaaagaaaa aagaaactat ttattctcga tattttgttt     4320

tgcacagcaa aggcagctgc tgacttctgg aagatcaatc aatgcgactt aaagtgattc     4380

agtgaaaaca aaaaacttgg tgggctgaag gcatcttcca gtttacccca ccttagggta     4440

tgggtgggtg agaagggcag ttgagatggc agcattgata tgaatgaaca ctccatagaa     4500

actgaattct cttttgtaca agatcacctg acatgattgg gaacagttgc ttttaattac     4560

agatttaatt tttttcttcg ttaaagtttt atgtaattta accctttgaa gacagaagta     4620

gttggatgaa atgcacagtc aattattata gaaactgata acagggagta cttgttcccc     4680

cttttgcctt cttaagtaca ttgtttaaaa ctagggaaaa agggtatgtg tatattgtaa     4740

actatggatg ttaacactca aagaggttaa gtcagtgaag taacctattc atcaccagta     4800

ccgctgtacc actaataaat tgtttgccaa atccttgtaa taacatctta attttagaca     4860

atcatgtcac tgtttttaat gtttattttt ttgtgtgtgt tgcgtgtatc atgtatttat     4920

ttgttggcaa actattgttt gttgattaaa atagcactgt tccagtcagc cactacttta     4980

tgacgtctga ggcacacccc tttccgaatt tcaaggacca aggtgacccg acctgtgtat     5040

gagagtgcca aatggtgttt ggcttttctt aacattcctt tttgtttgtt tgttttgttt     5100

tccttcttaa tgaactaaat acgaatagat gcaacttagt ttttgtaata ctgaaatcga     5160

ttcaattgta taaacgatta taatttcttt catggaagca tgattcttct gattaaaaac     5220

tgtactccat attttatgct ggttgtctgc aagcttgtgc gatgttatgt tcatgttaat     5280

cctatttgta aaatgaagtg ttcccaacct tatgttaaaa gagagaagta aataacagac     5340

tgtattcagt tattttgccc tttattgagg aaccagattt gttttctttt tgtttgtaat     5400

ctcattttga aataatcagc aagttgaggt actttcttca aatgctttgt acaatataaa     5460

ctgttatgcc tttcagtgca ttactatggg aggagcaact aaaaaataaa gacttacaaa     5520

aaggagtatt ttt                                                        5533


<210>  2629
<211>  683
<212>  DNA
<213>  homo sapiens

<400>  2629
agcactgcag ggctctgggc gggaaggcta acctggtgcg gagccagcct gggtctcagc       60

cccgcgtacg gcctttcacg agtcttcaag ccttcaggct ttcttctagt caagatgagt      120

gataaaccag acttgtcgga agtggagaag tttgacaggt caaaactgaa gaaaactaat      180

actgaagaaa aaaatactct tccctcaaag gaaactatcc agcaggagaa agagtgtgtt      240

caaacatcat aaaatgggga tctcctccaa agagcagatt tcagcattgc ctgacagtct      300

tggttttagg cttgtttttt tgtaaacctg tgtgtttgta gagatttcag acatcttctg      360

atttcttctc acctatattc cctggttaag aggtcagggg tagtgaatgt ttccttaagt      420

tcctttttaa acttcccatt ggtatgtaaa ttccaaatgg cagatgctgt caataacctt      480

gccatggatg acctttgtgt aggtagtcct tgcacctcat gcaggataag ccaattttaa      540

ctttctacaa tgggtgcctc aatagtttca taatcttcat gaagttgcat cctttggcag      600

cttcttacag tttattttca cttccaatgt agcaataaaa taataaatat aatcgttgtt      660

gtctgaaaaa aaaaaaaaaa aaa                                              683


<210>  2630
<211>  4494
<212>  DNA
<213>  homo sapiens

<400>  2630
ggcccggccg gactgagttc gctgctgtcc cggttcctct cgagtcggct ccaactgcca       60

gcccgggttg gcgccatgta cgccgtgtac aaacaggcgc atccgcccac cggtctggag      120

ttctccatgt actgcaactt cttcaacaac agcgagcgca acctggtagt ggccgggacc      180

tcgcagctct acgtgtaccg cctcaaccgc gacgccgagg ctctgaccaa gaatgacagg      240

agcacagagg ggaaggccca ccgggagaag ctcgagcttg ctgcctcctt ctccttcttt      300

ggcaacgtca tgtccatggc cagcgtgcag ctggcaggag ccaagcggga tgccctgctc      360

ctaagcttca aggatgccaa gctgtctgtg gtggagtacg acccgggcac ccatgacctg      420

aagaccctgt cactgcacta ctttgaggag cctgagcttc gggacgggtt tgtgcagaat      480

gtacacacgc cgcgagtgcg ggtggacccc gacgggcgct gtgcagccat gcttgtctac      540

ggcacgcggc tggtggtcct gcccttccgc agggagagcc tggctgagga gcacgagggg      600

ctcgtgggtg aggggcagag gtccagcttc ctgcccagct acatcatcga cgtgcgggcc      660

ctagacgaga agctgctcaa catcatcgac ctgcagttcc tgcatggcta ctacgagcct      720

accctcctca tcctgtttga gcccaaccag acctggcctg ggcgcgtggc cgtgcggcag      780

gacacgtgct ccattgtggc catctcactg aacatcacgc agaaggtgca ccccgtcatc      840

tggtccctca ccagcctgcc ctttgactgc acccaggctc tggctgtgcc caagcccata      900

ggtggggtgg tggtgtttgc cgtcaactcg ctgttgtacc tgaaccagag cgtccccccg      960

tatggcgtgg ctctcaacag cctcaccaca ggaaccacgg ctttcccgct tcgcacccag     1020

gagggtgtgc ggatcaccct ggactgcgcc caggccacct tcatctccta cgacaagatg     1080

gtcatctccc tcaagggcgg cgagatctac gtgctgaccc tcatcaccga cggcatgcgc     1140

agtgtccgag cgttccactt tgacaaggcg gccgccagcg tcctcaccac cagcatggtc     1200

accatggagc ccgggtacct gttcctgggt tctcgcctgg gcaattccct cctcctcaag     1260

tacacggaga agctgcagga gcccccggcc agtgctgtcc gtgaggctgc cgacaaggaa     1320

gagcctccct caaagaagaa gcgagtggat gcgacggccg gctggtcagc tgcgggtaag     1380

tcggtgccgc aggatgaggt ggacgagatt gaagtgtacg gcagcgaggc ccagtcggga     1440

acacagctgg ccacctactc ctttgaggtg tgtgacagca tcctgaacat tggaccctgt     1500

gccaatgccg ccgtgggcga gcctgccttc ctctctgaag agtttcagaa cagccccgag     1560

ccggacctgg agattgtggt ttgctccggc cacgggaaga acggggcttt gtcggtgctg     1620

cagaagagca tccggcccca ggtggtgaca acctttgagc ttcccggctg ctatgacatg     1680

tggacagtca tcgccccggt gcgtaaggag gaggaggaca atcccaaggg ggagggcaca     1740

gagcaggaac ccagcaccac ccctgaagca gacgacgacg gccgcagaca cggattcctg     1800

attctgagcc gggaagactc caccatgatc ctgcagacgg ggcaggagat catggagctg     1860

gacaccagtg gcttcgccac tcagggcccc acggtctttg ctgggaacat cggggacaac     1920

cgctacattg tccaagtgtc accactgggc atccgcctgc tggaaggagt gaatcagctg     1980

cacttcatcc ccgtggacct gggcgccccc atcgtgcagt gcgccgtggc cgacccctat     2040

gtggtcatca tgagtgccga gggccacgtc accatgttcc tgctgaagag tgactcctac     2100

ggtggccgcc accaccgcct ggcgctgcac aagcccccgc tgcaccatca gtccaaggtg     2160

attacgctgt gcctgtaccg agacctcagc ggcatgttca ccactgagag ccgcctgggt     2220

ggggcccgtg acgagctcgg gggccgcagt ggcccggagg ccgagggcct gggctcagag     2280

actagcccca cagtggatga cgaggaggag atgctgtatg gggattcggg ctccctcttc     2340

agccccagca aggaggaggc ccgaagaagc agccagcccc ctgctgaccg ggaccctgca     2400

cccttccggg cagagcctac ccactggtgc ctgctggtgc gggagaatgg caccatggag     2460

atctaccagc ttcccgactg gcggctggtg ttcctggtga agaacttccc tgtggggcag     2520

cgggtccttg tggacagctc ctttggacag cccactacac agggcgaggc ccgcagggag     2580

gaggccacgc gccaggggga gctgcccctc gtcaaggagg tgctgctggt ggcgctgggc     2640

agccgccaga gcaggcccta cctgctggtg catgtggacc aagagctgct tatctacgag     2700

gccttccccc acgactctca gctcggccag ggcaatctca aagtccgctt taagaaggtc     2760

cctcacaaca tcaacttccg tgagaagaag ccaaagccat ccaagaagaa agcagaaggt     2820

ggcggcgcag aggagggggc tggggcccgg ggccgcgtgg cgcgtttccg ctacttcgag     2880

gatatttatg gctactcagg ggtcttcatc tgcggcccct cccctcactg gctcttggtg     2940

accggccgag gggctctgcg gctacacccc atggccatcg acggcccggt cgactctttc     3000

gctccattcc acaatgtcaa ctgtccccgc ggcttcctgt acttcaacag acagggcgag     3060

ctgaggatca gtgtcctgcc tgcctacctg tcctatgatg ccccatggcc tgtcaggaag     3120

atcccgctgc gctgcacggc ccactatgtg gcttaccacg tggagtctaa ggtgtatgct     3180

gtggccacca gcaccaacac gccgtgtgcc cgcatcccac gcatgactgg cgaggagaag     3240

gagtttgaga ccatcgagag agatgagcgg tacatccacc cccagcagga ggccttctcc     3300

atccagctca tctccccggt cagctgggag gctattccca atgccaggat cgagctgcag     3360

gagtgggagc atgtgacctg catgaagaca gtgtctctgc gcagtgagga gaccgtgtcg     3420

ggcctcaaag gctacgtggc cgccgggacc tgcctcatgc agggggagga ggtcacgtgc     3480

cgagggcgga tcttgatcat ggatgtgatt gaggtggtgc ccgagcctgg ccagcccttg     3540

accaagaaca agttcaaagt cctttacgag aaggagcaga aggggcccgt gaccgccctg     3600

tgccactgca atggccacct ggtgtcggcc atcggccaga agattttcct gtggagcctg     3660

cgggccagcg agctgacggg catggccttc atcgacacgc agctctacat acaccagatg     3720

atcagcgtca agaacttcat cctggcagcc gacgtcatga agagcatttc gctgctgcgc     3780

taccaggagg aaagcaagac gctgagcctg gtgtcgcggg atgccaagcc cctggaggtg     3840

tacagcgtgg acttcatggt ggacaatgcc cagctgggtt ttctggtgtc tgaccgcgac     3900

cgcaacctca tggtgtacat gtacctgccc gaagccaagg agagtttcgg gggcatgcgc     3960

ctgctgcgtc gggcagactt ccacgtgggt gcccacgtga acacgttctg gaggaccccg     4020

tgccgggggg ccactgaagg gctcagcaaa aagtcggtcg tgtgggagaa taagcacatc     4080

acgtggtttg ccaccctgga cggcggcatc gggctgctgc tgcccatgca ggagaagacc     4140

taccggcggc tgctgatgct gcagaacgcg ctgaccacca tgctgccaca ccacgccggc     4200

ctcaaccccc gcgccttccg gatgctgcac gtggaccgcc gcaccctcca gaatgccgtg     4260

cgcaacgtgc tggatgggga gctgctcaac cgctacctgt acctgagcac catggagcgc     4320

agcgagctag ccaagaagat cggcaccaca ccagacataa tcctggacga cttgctggag     4380

acggaccgcg tcaccgccca cttctagccc cgtggatgcc gtcaccacca gcacacggaa     4440

ctacctccca cccccttttt gtacaaaaca caaggaaaaa cattttttgc ttga           4494


<210>  2631
<211>  10669
<212>  DNA
<213>  homo sapiens

<400>  2631
tgtggctcgg gcggcggcgg cgcggcggcg gcagaggggg ctccggggtc ggaccatccg       60

ctctccctgc gctctccgca ccgcggctta aatgatgtat tttgtgatcg cagcgatgaa      120

agctcaaatt gaaattattc catgcaagat ctgtggagac aaatcatcag gaatccatta      180

tggtgtcatt acatgtgaag gctgcaaggg ctttttcagg agaagtcagc aaagcaatgc      240

cacctactcc tgtcctcgtc agaagaactg tttgattgat cgaaccagta gaaaccgctg      300

ccaacactgt cgattacaga aatgccttgc cgtagggatg tctcgagatg ctgtaaaatt      360

tggccgaatg tcaaaaaagc agagagacag cttgtatgca gaagtacaga aacaccggat      420

gcagcagcag cagcgcgacc accagcagca gcctggagag gctgagccgc tgacgcccac      480

ctacaacatc tcggccaacg ggctgacgga acttcacgac gacctcagta actacattga      540

cgggcacacc cctgagggga gtaaggcaga ctccgccgtc agcagcttct acctggacat      600

acagccttcc ccagaccagt caggtcttga tatcaatgga atcaaaccag aaccaatatg      660

tgactacaca ccagcatcag gcttctttcc ctactgttcg ttcaccaacg gcgagacttc      720

cccaactgtg tccatggcag aattagaaca ccttgcacag aatatatcta aatcgcatct      780

ggaaacctgc caatacttga gagaagagct ccagcagata acgtggcaga cctttttaca      840

ggaagaaatt gagaactatc aaaacaagca gcgggaggtg atgtggcaat tgtgtgccat      900

caaaattaca gaagctatac agtatgtggt ggagtttgcc aaacgcattg atggatttat      960

ggaactgtgt caaaatgatc aaattgtgct tctaaaagca ggttctctag aggtggtgtt     1020

tatcagaatg tgccgtgcct ttgactctca gaacaacacc gtgtactttg atgggaagta     1080

tgccagcccc gacgtcttca aatccttagg ttgtgaagac tttattagct ttgtgtttga     1140

atttggaaag agtttatgtt ctatgcacct gactgaagat gaaattgcat tattttctgc     1200

atttgtactg atgtcagcag atcgctcatg gctgcaagaa aaggtaaaaa ttgaaaaact     1260

gcaacagaaa attcagctag ctcttcaaca cgtcctacag aagaatcacc gagaagatgg     1320

aatactaaca aagttaatat gcaaggtgtc tacattaaga gccttatgtg gacgacatac     1380

agaaaagcta atggcattta aagcaatata cccagacatt gtgcgacttc attttcctcc     1440

attatacaag gagttgttca cttcagaatt tgagccagca atgcaaattg atgggtaaat     1500

gttatcacct aagcacttct agaatgtctg aagtacaaac atgaaaaaca aacaaaaaaa     1560

ttaaccgaga cactttatat ggccctgcac agacctggag cgccacacac tgcacatctt     1620

ttggtgatcg gggtcaggca aaggagggga aacaatgaaa acaaataaaa gttgaacttg     1680

tttttctcat gcatatgatt tccattatgc ctacagatat ggaccctttt tctgtcttga     1740

cttcttgatc attgacctct gtttacaaca ggaggagggt actaaagtcg gaggatttcc     1800

ttttcttgta gctcactgcc cacagacttt ctacagagtc accaatctgt cagtaacaac     1860

agagagtcca gcaataatcg gtgactggtg tgcatagcgg aggttgcggc attactttgc     1920

acaactagct ctttgtttca tgaaggaagt ttttattttt tcaccgatta ttgccagtcc     1980

gcaggatggc atgaaaaggg tccatagcag tagcaacaat agcattataa tatattacag     2040

ggtaaatggg catgaagact atatatagct aaaagagata ttgtttatat attgttttaa     2100

gtaatataaa atgtagttac tggtgtagct tttcctgttg aattgataag gcactttcat     2160

tttgcacctt tttctttaaa ttaaatgcta gcgtgttcac tgtcgtgtcg catgtgcacc     2220

agaaacacaa gtttaactga gaaggcttgg aaggtacgtt gggaggtatt tatgctgctg     2280

tttacaaaat tatttttaag agactggctg gtcatatcta gaaatcacca cgttggattt     2340

tttttttaac atgtgaattt ggaattagaa acggaactct ccctaaatta tactttgctt     2400

tttggtaagt ttaatgatag atgtgtttat gcttcataca aagttgaatg attgattggc     2460

gtggtggaca tataccatca tgctcatttt ttttttttaa agctttttaa aatgccacct     2520

catggaggcg agggggagga gaagctcatt ttacacaatt cagtagttaa atatggactc     2580

ggtctcaact tggaattctt atgctttgag aacaaatcaa caaccagaat atttattgga     2640

atctagcttt tattataaga aggacccaaa gattatatcc tgagcaaatg cacactcccc     2700

atgtgaggac atgaagtatt tactttgtga atgtttatgt tcttggtata atctaggaac     2760

cctatgagtt tatctcagag tgaactaatt ctagatttgt tgtcaataga tgctataatt     2820

caagaatgtt gctctccata tttgaaaaac gatggatagg agggtgaggg aagcatacaa     2880

tgttgaacca gtttctctta tttaaatatt aaatacttta agcctttaaa gtgaagttga     2940

tgctagctgc aaacatttac tcttgtattt atcttcacta ggaaactgtg gactgtaatt     3000

tattttatta aatatttaga agattatttg gcttgtgtgt tcaggtgaga aatactgagt     3060

tgtttttgtt taatttcatg gttttttttt ttttaatgat ccctagtggg ggaaggggaa     3120

aggaatagtc tgataaacag atgtgcatat tttaaaaaca agtgaccttt tgggaatgta     3180

ggcatttaga cgatgatttt agtcgcacta ggggtgggat tcaaactact ggtcaaagac     3240

cattttgtac agaaaaggga acatctccga tgggtgttaa ggtaggagtt tccatgcagc     3300

cctttatgtc tgagaaatag tctcctctgc cattggggtc cctgcggaat cttctacagg     3360

aattgcagct cttcacgtca tgctaggtta ccagcatggg cttcccagag cacttcactc     3420

tgtttctaac tccactgact tttctgactt gtttcttgag ggacttggaa aaggggaagg     3480

tattattcac acagatgtgt gtatgaagcc taaataacat ccaacttttt ttccaaaaac     3540

atagtaagag tttaaccata aatagaagag taatattcct ttaaatttct tacaggcatg     3600

taaaatttta tgtgtttata gagagatgct aactgtcagc atatagtatt tatattgggg     3660

caagaagggt taaatcaaat ctttaattta agtaagcata gttcctttaa agatcagtag     3720

tatttatact ctgaaaagag taccaagctt agttcagtta tttattcatc catttttttt     3780

ctattgtttc tcctctgggg ggaaatggtg ttttgttttt gtttgagttt tgtgttttag     3840

ttttttggtt ttggttttgt tttgtttttt tgtcattcag attcactaaa tttggggatg     3900

gttttattaa agtatattaa cttcttttta accaaagctt tctgaatatg accagcctca     3960

ggtgctagcg cattaaagag caactaaacc taattccagt gtcgatttgt gaaataataa     4020

aagctaattg aatttctcta agggtgagag agaacataat gatgaactta aaaagaaatt     4080

ccttttccca gaagggattc tgcatgtacc tacaaacaat catgctctaa ccacagtaat     4140

agtcatgcca tggtgacatt gcttttacgg taaaccaaga taggtaatat gatgcttctt     4200

cccaggtgtt tctgaaagaa aagcagcggt ggagcttaag agccaagtcc actgattgac     4260

ataataggat ggaattgtag acagagacat gctccatgaa acaaggaaac aactgactac     4320

tatttggatc taagttggga tctgatgtta aacaataaat tcagtttaaa aaaaatatgg     4380

agctcagaaa aggatgtgaa aaactttgca ttttcctttc ttcattatta caaaaacacc     4440

tatgtgatga cataaaatac ttgggtgata tcagaacaat tatccttaat agtttttata     4500

attaaagttt cctaaacttc agtctccaat agtcttttaa ggattggaac cacatcactg     4560

tcagccccgc tgctacaatg cctttgtaca atttttttac ataaggcaaa taaggctttt     4620

gtacaaagcc tgaatacctt ctgttccaat ggtgtccaaa tggttattat attgtgaaaa     4680

acctggcctt ggtcacaatg caaacaaaag tacagatgaa agtgcttttt ggacagtttg     4740

caaattgtgt taaagctacg gatttttttt aaagtgttca gcatcttaac gtgtattaaa     4800

gctatggatt tttttttaaa gtcttcagca tcctaattca ccctttctaa cttaagaaaa     4860

acatgactta agacactgct tctaagtttg gttgttcttt atagtgtgga tacccagtta     4920

tctgtgagcg tatgggggtg ggctgagggt caggtgagga aggagtgtgt gtgtgtgtgt     4980

gtgtgtgtgt gtgtgtgtgt gtgatttgca tgtgtatgat gtgtgtgcgt cggaccgctt     5040

ctaggctact aagtgtcaat ggaaaagaaa atgtattcaa aatacttaaa tcaaaactag     5100

aagatgggga aaaaaagatt tattctatac aaagccttgt ctggaccact ttagagagac     5160

ttctattttt ttaacccttc tataaatatt tgatggcact tgaaatattc ctgcaataaa     5220

atgtgatttg tgtaaagaaa aaaagatttt gtaatgtgaa acaaagaaag aaagtaatgt     5280

aattttctaa aaaaaaaaat acaaacaaac aaactttgta ttattttctt gatggaattt     5340

gtctatctgt ctttggaaaa ctttttattt cattgaatgt gccatagtag aaatgtgtgt     5400

ttttagtttt agactaagga atagctagtt gttgtgttcc gacattccaa aatgcaaaac     5460

aacctagtag tatctttcat gaaaaggttt aagtagtatg taagcttctc tcattgttgc     5520

ttttttgcac atgttcttca ttcctctcta gtgcaatatg tacatagagc acttgcgggt     5580

gtaccttgat ccctcaggga aaaatacata tttgtacagt tttttggggt ttttttgttt     5640

tttggttttt tttgttttgc cttttgtttt tggctaagga atgtcgatcg aatcacttgt     5700

tattgttgag gggcagccag ataataatcc taaagccact gtttccaaca ttgattgttt     5760

aaatcatatg tccttccaat gctattattt taagataata ataaaaagtt attttctgac     5820

agttctttgt gctgactggt gaaaaacaag ggtaaataag caccttataa ttgacttact     5880

gtgaatgaca atccatcttg gtatcaacga tagaagccct atcattttgg agttggggtt     5940

aagagtcaga aacaatgtgc tcagggatct cctaaaactc ttaaaacagg gtggccagta     6000

ctactgggac aaattgtgtt ttttattatt aataataatg ataataatac tatccctcca     6060

aggcacaagt gaactatata gaactgcgtg tgtgtaaact ctttactctc gtctcatttt     6120

gttgagttta gaacttgatg tgctcgtcag tcttgtgttt caaaacactg aataacttcc     6180

aaagcaaagt tatgccagtg tgttcaaaag ataaattaat aatgtaccag caaagagcat     6240

cattcaaagt atagtccttg catattccag ttaccatttc tctaataatt aaaatattca     6300

tgataaatat atatatagca tcatatgtta aaaactattt caaattctac atattaagga     6360

tgaaaatttt aaaatccagt aataagagga gagacctgcc tatcagtaca gtgatatagg     6420

taaaagatga aatatgtttt taaaatacca gcaattaact attgttttca tgggttctcc     6480

tctagaagca aaccaaaaat tccttcatgg aaaacaattc ttacttctac atgtgtagtt     6540

tatatctgat gcattacaag agctaatgtt taaagacaaa acaaaacctg cctgtatgac     6600

agcagcaact cgagccaaca tttagtgtta catgttatat ttttgaaata ccgttttgtt     6660

atcatattcc acatattact ttccataaag tcagagaagt tcaatgtaat tgttggctct     6720

gattcttcca ccttgggata cacattcaca agaagattta tatattttct tactatgata     6780

gaggaacata atctgggaaa acttcccatg tctgtaagat gaaaaggata cctttaccat     6840

gttgtttttg ataataaaga atatggaaaa tggtagaaat ctctcctctc tatgtgtatt     6900

tgtatatgtg tgtatacaca cacacgttga catttttaca taacatgtga ttgccacttc     6960

ttataaagtt atgatataga accccatgaa aacaacttta tattatagat caaataatgt     7020

gcccagaaac gcaattgcaa cagtaaatct tgatctattg gtaagagtct atgatacagg     7080

tcttcattct atccctaaac ataatgttag taaagaggtt ccatcagatt gtattataga     7140

gaccttccta ttgctattta tttttaagag atgagaagac tgactagcaa tgtctccaca     7200

gtgcaattgg tttcacttct gggtctgtct gtctgtttgt gtaggtgaga tcagtgttgt     7260

caggctctca gaataatttt taaaagaatc cagaagcctg acttcacacc aagtagccat     7320

cctagatggg cgggggggat ctccatgttc aaccaaaccc tcagaactta gagcaataaa     7380

tacattcagt catttattta taaatgaatg acagaatatt caatccaaat agaaacaacc     7440

ttttgtcagt gatgcaacat aacatggagt cttatattga gaaagtgaat atgaatattt     7500

taaatagatg cctaggaaat ctgtgtttgc tgtttacatt taatgtactt tgccacatta     7560

gcagtaccac acttctttta ctttcatcct tctaagaact aatgaaagat agcttgctat     7620

tagctttgac atgttgcaca tgccattatg ttgttctcta agaacaacta aattctctcc     7680

agtgttcatg tgtgattcct ttttcatcat tattacttta atgtggatga atactatttc     7740

taggaacttg attatcactg aacagattgc atatgtaaat gcagataatt cttgagcaat     7800

atagtgaaaa tgatttcaca aaaaaaatcc atatgtactg tatacatctt cctgaatcca     7860

aaattctcct gttatccaca cagtttgaaa tctcatatta aacagtggta aatttttaaa     7920

cattaggaca ttagctggct gcttctataa atgtacctgt attgtctgcc tgctcctttt     7980

gtggagatgt gtttttgtat tggatgtttg ggccaatggg aggcttcaag ctacaacata     8040

ttttcccact ttaaataata tttaacatat gacaaacccc agacaaggct tttaatatgt     8100

ataaagaact gcagtgttag gtggtttatt tgcaaactgt tttcagtgtt gtccattttt     8160

atggcacctt taacaatatt cttgtttcca aagtacaaaa aaaataggtt aaataatcta     8220

gccataactg aatgtcaagc aataaaacaa atgacttttg tgcatagact taaaaaatac     8280

aaattttaga catctgcatg taaatgcaat ctcttgttta ctgctttctt caacttgagc     8340

aatcgattcc ttatttacta ttaacttaag aacttgtaac ggcctgtaaa cattttctct     8400

cttactcttc tttcaaattt acctgtccct gcttttgagt cataatattt aatgttgttc     8460

tgcacatctc tatacagtta actttttggc tttcattctg tatagataag aaaatgttat     8520

attataaaca gcctactcag tgcaaatatt tatctgttta tcaaatccac aatatgctgt     8580

ataataccgg ttttactata taatctattt tagacatagc tgtttagaac tagagtgtgc     8640

tatttttgtg tttttctgat gtgtggtgct agacaagtta cttttgtgaa caacaaaaat     8700

tatccctttt attcctagac aataccacct ttgggtcttg ttaatttcac tgagtataac     8760

tatatatttg tatatatata catatatata tatatctacc tatgcccaac tggcagctgt     8820

atcagagtgc tggatttggg acatgctttt ctctttaaat acataatatc attatataaa     8880

ttattctaga gtgtatttaa ttaggataaa attacttcct tagtatggat atttgacatc     8940

tatagggtga atttgtttat aaatatggct atatggaaac ttattagcat ttactttatg     9000

tttgctactt ggctttacag catatctcct aagctgaaaa ataatttgcc aggccttcaa     9060

gatcctaaag aaacttgttt aatggagtaa tatacttttt tttcttatta aggaattgta     9120

ttactggcac ctaacacagt tgtattctta gctcctatta tagataatgg gcatttacat     9180

aaaatatcct agatggcttg atggcagaat aaacctttcc cctcctacct gagtcatgag     9240

aaggatggag acgtcctctg ccataacatg ggccataaag caaattcgac atgggatgtt     9300

ctgtttcagt atgacctcaa ccagttccat gaactgagtg aaggaccttc attttcaaag     9360

ttatttaata agtagcttaa ttaagccttt ctacccattc tcccaagatc tactggcatt     9420

attgaaaagc aaagtttatc aaatatctaa ctaaggatgt agttaacctt attaaatatt     9480

gattagaatt gttctgtaat attactgaat ttgtaagatc tttagcaaag atttttgagc     9540

aatttataaa tgtagagcaa atgtttctgt ttactgcact ttttgtaact gaaggtgata     9600

aattctcaag ccatgattat tggcttccat gcactgcaat atttatccac aattctagac     9660

attttccatt tttgtggaag agttgctgtt accttaatta taaatgcaat tgtgtggtta     9720

atgagagcta atgctagtag ttaacctttt aaagtggatt ggctacagtt gagggagaaa     9780

tctcttttaa tataaatcac atcattcctt aactgcctct cttggaaaga gattgaaacc     9840

ttttttttaa agcacgattt agcatcctaa gcttcctgag ggtagagatt gtatcttttt     9900

gcgtctgcac aatggctagc acatgtcagc atttgacaat tgttaaatga taacaagtgt     9960

gccccaatta aaacgttttt cctgggttgt tttgttaaat ttacaaagta agccaagcct    10020

tacggttaac attctcctct acaaccaagt attaaagcca catttaaaaa gaccacatga    10080

aatgctgatt ctaattgtgt gtaggtcttg aggattaagc acacaaattt cacaaacttc    10140

tgtttgagta aacaaactca gccttctgta aatatacatg caagtttgga aacagtaata    10200

ctgtacctat aaatatatgc tgtctgtttt gtgtacagta tgtaaaaact ccttttctgc    10260

cacactaaaa atgcaagcca tttatgggaa tcctaaaact agtattgaac taaaactttg    10320

ctaatgatct ttattagagg atcgtccaac ttttcactta ccttgggttt tcttttcaat    10380

tcactcttac actagtctgc ttatttccag ctgtttattt tattgagtcc tgaatttaaa    10440

aaaaaaatat tttgattcat tttgtaaata caagctgtac aaaaaagaga gatttaatgt    10500

tgtcttttaa atactccaat tttcattcta atatgaatgt tgttatattg tacttagaaa    10560

ctgtaccttt aatattacat tacctttatt aaaagtgcat tgaacacatc aattttagat    10620

gtgctttatg tactgttatc ctataataaa acttcagctt ctaatggaa                10669


<210>  2632
<211>  2324
<212>  DNA
<213>  homo sapiens

<400>  2632
gtaactctac ggcctagcaa ccgttgccaa ggagctcgac tctgggagcg gtctagagcc       60

cgggcgcctc ctggggggtg gggaaacggt ttcgtgagga gaatttgagg taacctcgcc      120

aactcgcggt cggaagctcc tctgaacccc gaaataggag agagctcccg tcctctctcg      180

gtcctgatgc agcacctcgc aagtggaagg ggtcgtcgcg gttaagcccc cggatagggg      240

aatcgggccc cttctgggat tcgagcggat ccaggccgct ccctggaggg atgaactgtc      300

gaggggccca gggcagcccc cgctagaggc ccggtcgggt gtggggtccc ctgtcccctg      360

tcccgagccc ggggaggggg acactatttc tggtactccc aggaggctgc gggtcgatgc      420

tcgtgccagc ctgggaccca ggcagcacgg tttctctccc aaattgtgcc agagaacacg      480

cacgtcctgg ttttcattgt tccccgcctc ctgcgactcg tttgtggtta aaattataag      540

acctaattat gagtgatcaa attaaattca ttatggacag tctcaataag gagcccttta      600

ggaagaacta taatttaatc acgtttgatt ccttggagcc aatgcaacta ttacaagttc      660

tcagtgatgt tctggctgag attgacccaa agcaacttgt ggatatcaga gaggagatgc      720

cagagcagac agccaaacga atgttgagcc ttcttggtat tcttaagtac aaaccttcag      780

gaaatgccac agatatgagt acttttcgtc agggtttggt gattggaagt aaacctgtaa      840

tttacccagt gctccactgg cttcttcaga ggactaatga actgaagaaa agagcatatt      900

tagctcgttt tttaataaaa cttgaggtac caagtgagtt tcttcaggat gaaactgtgg      960

ctgacaccaa taaacagtat gaagagttaa tggaagcctt taaaactttg cataaagaat     1020

atgagcagct caagatatct ggattttcta cagcagaaat aagaaaggat atcagtgcaa     1080

tggaagaaga aaaggatcag ctcattaaga gagttgaaca tttgaagaaa agggttgaga     1140

cagctcagaa tcatcaatgg atgcttaaaa tagcaaggca acttcgagtt gaaaaagaga     1200

gagaagaata tcttgcacaa cagaaacagg aacaaaagaa tcagctattt catgcagtgc     1260

aaagattgca aagagtacaa aaccagctga aaagcatgcg ccaagctgca gcagatgcaa     1320

agcctgaaag tttaatgaag aggctagagg aggagataaa atttaattta tatatggtaa     1380

ctgaaaaatt tcctaaagaa ttagaaaata agaaaaagga attacatttt ttacaaaaag     1440

tagtttcaga gccagctatg ggccattctg atcttcttga acttgaatct aaaataaatg     1500

aaataaacac agaaattaac cagttgattg aaaagaaaat gatgagaaat gagcccattg     1560

aaggcaaact ctcactgtat aggcaacagg catctatcat ttcccgtaaa aaagaagcca     1620

aagctgagga acttcaggag gccaaggaga agttagccag cctagagaga gaagcatcag     1680

taaagagaaa tcagacccgt gaatttgatg gtactgaagt tttaaaggga gatgagagac     1740

aggatctcac tctgtcaccc aggctggagt gcggtggtgt gatcatggct tactgcagcc     1800

tgaaactcct aggctcaagt gatcctccta cctcagcctc ctgagaagct cggactacag     1860

gcacgagcca ccatgcccag ctaattttct ttttttgttt tgttttgtag agatgtggtc     1920

tcactatgtt tcccaggctg gtcttaaact cccggcctca agcagtcctc ccacttcggc     1980

ctcctgaagt gttaggatta caggcgtgag cctgcgcctg gctgtaatta ctatacccag     2040

tttttacaga taaaggatct gagacatgca gaggttttaa gctgacttgc ctgacacccc     2100

attgctagta agtagtagaa ccaggagttg gatttagcag tctggctgta gagtcatcaa     2160

tagtttgcac atgacagaaa gctggaagaa atagtcaacc tgaaacacat gatggaatta     2220

taattcagaa tcatcttggt agataggggc actgtgctta aacaaaatgc cattaatggg     2280

attataataa atataatgtg gtagaattca aaaaaaaaaa aaaa                      2324


<210>  2633
<211>  2175
<212>  DNA
<213>  homo sapiens

<400>  2633
ggggaggcgc ggcgcgccgg ggacagcggc ggacggcggc ggcggcggca tgcggctcct       60

cgcgctgccc atcgtgggct gaggcggccg cagaaccggc gggaggcgcg gcggccgggc      120

gagccgaggg cgcagccagc cgggcggacc gcggacagcg gtcggggcgc cgcgccatgg      180

ggcgagccgg gggcgggggc ccgggccggg ggccgccgcc actgctgctg tttctggggg      240

ccgcgctggt cctggcctct ggggccgtgc cggcgcgtga ggcgggcagc gcggttgagg      300

ccgaagagct ggtgaagggc agcccggcgt gggagccgcc tgccaacgac acgcgggaag      360

aagccggccc accagcggct ggggaagatg aggcgtcgtg gacggcgccc ggtggcgagc      420

tggccgggcc agaagaggtg ctgcaggagt cggctgcggt gaccggcacc gcctggctgg      480

aagctgacag cccaggcctg ggaggagtga ccgcagaggc gggcagcggc gatgcccagg      540

cccttccagc tacgctccag gctccccacg aggtcctcgg gcagtcaatc atgccccctg      600

ccattcctga ggctacagag gccagcgggc caccctcccc cacccccggc gacaagctga      660

gcccagcttc tgaactcccc aaggagagcc ccttggaggt ttggctgaac ctggggggca      720

gcacacccga ccctcaaggg ccagagctga cttacccatt tcagggcacc ctggagcccc      780

aaccggcatc agatatcatt gacatcgact acttcgaagg actggatggt gagggtcgtg      840

gcgcagatct ggggagcttc ccagggtcac caggaacctc agagaaccac cctgatactg      900

agggagagac cccttcctgg agcctgcttg acttatacga tgatttcacc cccttcgatg      960

aatctgattt ctaccccacc acatcctttt atgatgactt ggatgaagag gaggaggaag     1020

aggaggatga caaagatgca gtaggaggtg gagacctaga agatgaaaat gagcttctag     1080

tgcccactgg gaagcctggt ctggggcccg ggacaggcca gcccaccagt cggtggcatg     1140

ctgtccctcc acagcacact ctggggtcgg tccccggcag cagcatcgcc ctcaggcccc     1200

gcccaggaga gccaggcagg gacttggcct ccagtgaaaa tggcactgag tgccgcagtg     1260

gctttgtgcg gcataacggc tcctgccggt cagtgtgcga cctcttccca agttactgtc     1320

acaatggcgg ccagtgctac ctggtggaga acataggggc cttctgcagg tgcaacacgc     1380

aggactacat ctggcacaag gggatgcgct gcgagtccat catcaccgac ttccaggtga     1440

tgtgcgtggc cgtgggctcg gctgccctcg tcctgctcct gctcttcatg atgacggtgt     1500

tctttgccaa gaagctctac ctgctcaaga cggagaatac caagctgcgt aggaccaaca     1560

aattccggac cccatctgag ctccacaatg ataacttctc cctctccacc attgccgagg     1620

gctctcaccc aaatgatgat cctagtgctc cccacaaaat ccaggaggtt ctcaagtcct     1680

gcctgaaaga ggaggagtca tttaacatcc agaactccat gtcgcccaaa cttgagggtg     1740

gcaaaggtga ccaggctgac ttggatgtga actgtcttca gaataattta acctaaagca     1800

gagcaagaag agaggaagcg ggggtagtgg gtggggggta ggggaagaaa cattatctcc     1860

tcttgtacag agtctatttc ttgtaaccat ttgttaaact cttttctttt tctgatctca     1920

tggcatgctt ttatgtattt tgtacaggag gcaaaaaaat acttaaaata agcaaagaaa     1980

ctgaacagaa ttgcatacat tgggttgttt tttctgtgct gtctgtacat tgcttctgct     2040

gctgtgattt ctaaacctgt gctgttattc aactgacttt tttttgtact ttgacccacg     2100

tttttttgaa ataccagtaa aaaacaaagt tcttgaaata aaacttttta aaaagttaaa     2160

aaaaaaaaaa aaaaa                                                      2175


<210>  2634
<211>  3284
<212>  DNA
<213>  homo sapiens

<400>  2634
cccgtgcacc ctgtcccagc cgtcctgtcc tggctgctcg ctctgcttcg ctgcgcctcc       60

actatgctct ccctccgtgt cccgctcgcg cccatcacgg acccgcagca gctgcagctc      120

tcgccgctga aggggctcag cttggtcgac aaggagaaca cgccgccggc cctgagcggg      180

acccgcgtcc tggccagcaa gaccgcgagg aggatcttcc aggagcccac ggagccgaaa      240

actaaagcag ctgcccccgg cgtggaggat gagccgctgc tgagagaaaa cccccgccgc      300

tttgtcatct tccccatcga gtaccatgat atctggcaga tgtataagaa ggcagaggct      360

tccttttgga ccgccgagga ggtggacctc tccaaggaca ttcagcactg ggaatccctg      420

aaacccgagg agagatattt tatatcccat gttctggctt tctttgcagc aagcgatggc      480

atagtaaatg aaaacttggt ggagcgattt agccaagaag ttcagattac agaagcccgc      540

tgtttctatg gcttccaaat tgccatggaa aacatacatt ctgaaatgta tagtcttctt      600

attgacactt acataaaaga tcccaaagaa agggaatttc tcttcaatgc cattgaaacg      660

atgccttgtg tcaagaagaa ggcagactgg gccttgcgct ggattgggga caaagaggct      720

acctatggtg aacgtgttgt agcctttgct gcagtggaag gcattttctt ttccggttct      780

tttgcgtcga tattctggct caagaaacga ggactgatgc ctggcctcac attttctaat      840

gaacttatta gcagagatga gggtttacac tgtgattttg cttgcctgat gttcaaacac      900

ctggtacaca aaccatcgga ggagagagta agagaaataa ttatcaatgc tgttcggata      960

gaacaggagt tcctcactga ggccttgcct gtgaagctca ttgggatgaa ttgcactcta     1020

atgaagcaat acattgagtt tgtggcagac agacttatgc tggaactggg ttttagcaag     1080

gttttcagag tagagaaccc atttgacttt atggagaata tttcactgga aggaaagact     1140

aacttctttg agaagagagt aggcgagtat cagaggatgg gagtgatgtc aagtccaaca     1200

gagaattctt ttaccttgga tgctgacttc taaatgaact gaagatgtgc ccttacttgg     1260

ctgatttttt ttttccatct cataagaaaa atcagctgaa gtgttaccaa ctagccacac     1320

catgaattgt ccgtaatgtt cattaacagc atctttaaaa ctgtgtagct acctcacaac     1380

cagtcctgtc tgtttatagt gctggtagta tcaccttttg ccagaaggcc tggctggctg     1440

tgacttacca tagcagtgac aatggcagtc ttggctttaa agtgaggggt gaccctttag     1500

tgagcttagc acagcgggat taaacagtcc tttaaccagc acagccagtt aaaagatgca     1560

gcctcactgc ttcaacgcag attttaatgt ttacttaaat ataaacctgg cactttacaa     1620

acaaataaac attgtttgta ctcacaaggc gataatagct tgatttattt ggtttctaca     1680

ccaaatacat tctcctgacc actaatggga gccaattcac aattcactaa gtgactaaag     1740

taagttaaac ttgtgtagac taagcatgta atttttaagt tttattttaa tgaattaaaa     1800

tatttgttaa ccaactttaa agtcagtcct gtgtatacct agatattagt cagttggtgc     1860

cagatagaag acaggttgtg tttttatcct gtggcttgtg tagtgtcctg ggattctctg     1920

ccccctctga gtagagtgtt gtgggataaa ggaatctctc agggcaagga gcttcttaag     1980

ttaaatcact agaaatttag gggtgatctg ggccttcata tgtgtgagaa gccgtttcat     2040

tttatttctc actgtatttt cctcaacgtc tggttgatga gaaaaaattc ttgaagagtt     2100

ttcatatgtg ggagctaagg tagtattgta aaatttcaag tcatccttaa acaaaatgat     2160

ccacctaaga tcttgcccct gttaagtggt gaaatcaact agaggtggtt cctacaagtt     2220

gttcattcta gttttgtttg gtgtaagtag gttgtgtgag ttaattcatt tatatttact     2280

atgtctgtta aatcagaaat tttttattat ctatgttctt ctagatttta cctgtagttc     2340

atacttcagt cacccagtgt cttattctgg cattgtctaa atctgagcat tgtctagggg     2400

gatcttaaac tttagtagga aaccatgagc tgttaataca gtttccattc aaatattaat     2460

ttcagaatga aacataattt tttttttttt ttttgagatg gagtctcgct ctgttgccca     2520

ggctggagtg cagtggcgcg attttggctc actgtaacct ccatctcctg ggttcaagca     2580

attctcctgt ctcagcctcc ctagtagctg ggactgcagg tatgtgctac cacacctggc     2640

taatttttgt atttttagta gagatggagt ttcaccatat tggtcaggct ggtcttgaac     2700

tcctgacctc aggtgatcca cccacctcgg cctcccaaag tgctgggatt gcaggcgtga     2760

taaacaaata ttcttaatag ggctactttg aattaatctg cctttatgtt tgggagaaga     2820

aagctgagac attgcatgaa agatgatgag agataaatgt tgatcttttg gccccatttg     2880

ttaattgtat tcagtatttg aacgtcgtcc tgtttattgt tagttttctt catcatttat     2940

tgtatagaca atttttaaat ctctgtaata tgatacattt tcctatcttt taagttattg     3000

ttacctaaag ttaatccaga ttatatggtc cttatatgtg tacaacatta aaatgaaagg     3060

ctttgtcttg cattgtgagg tacaggcgga agttggaatc aggttttagg attctgtctc     3120

tcattagctg aataatgtga ggattaactt ctgccagctc agaccatttc ctaatcagtt     3180

gaaagggaaa caagtatttc agtctcaaaa ttgaataatg cacaagtctt aagtgattaa     3240

aataaaactg ttcttatgtc agtttcaaaa aaaaaaaaaa aaaa                      3284


<210>  2635
<211>  3782
<212>  DNA
<213>  homo sapiens

<400>  2635
gtctttacgt agacgtcggg ggcgcagccg cgctgtgcgc ggtgactggc ggctgcactg       60

gcggcagctg gaggtgtaat agtgcgggta gtgggtttgg agaagttccg aggcggcggt      120

ggcgccggtc aggacaagga tagcggaacc gggccctggg cttgtcgctc accatgccga      180

cagtagagga gctttaccgc aattatggca tcctggccga tgccacggag caagtgggcc      240

agcataaaga tgcctatcaa gtgatattgg atggtgtgaa aggtggtact aaggaaaagc      300

gattagcagc tcaatttatt ccgaaattct ttaagcattt tccagaattg gctgattctg      360

ctatcaatgc acagttagac ctctgtgagg atgaagatgt atctattcga cgtcaagcaa      420

ttaaagaact gcctcaattt gccactggag aaaatcttcc tcgagtggca gatatactaa      480

cgcaactttt gcagacagat gactctgcag aatttaacct agtgaacaat gccctattaa      540

gtatatttaa aatggatgca aaagggactt taggtgggtt gttcagccaa atacttcaag      600

gagaggacat tgttagagaa cgagcaatta aattcctttc tacaaaactt aagactttac      660

cagatgaagt cttaacaaag gaagtggaag agcttatact aactgaatcc aaaaaggtcc      720

tagaagatgt gactggtgaa gaatttgttc tatttatgaa gatactgtct gggttaaaaa      780

gcttacagac agtgagtgga agacagcaac ttgtagagtt ggtggctgaa caggccgacc      840

tagaacagac cttcaatccc tcggatcctg actgtgtgga caggctctta cagtgcactc      900

ggcaggcagt acccctcttc tctaaaaatg tccattccac aaggtttgtg acatatttct      960

gtgagcaggt tctccctaac ctcggtacct tgactacccc agtggaaggt cttgatatac     1020

agttggaggt attgaaattg ttggcggaga tgagttcatt ttgtggtgac atggaaaaac     1080

tagaaacaaa tttaaggaaa ctatttgata agttattgga atacatgccc ctccctccag     1140

aagaggcaga aaatggagag aatgctggta atgaagaacc caagctacag ttcagttatg     1200

tggaatgttt gttgtacagt tttcaccagt tgggccgaaa acttccagat ttcttaacag     1260

ccaaactgaa tgcagaaaag ctcaaagatt tcaaaatcag gctgcagtac tttgcacggg     1320

gcctgcaagt ttatatcaga caacttcgct tagctctcca gggtaaaacg ggtgaggcct     1380

taaaaacaga agagaacaag attaaagtcg ttgcattgaa aataacaaac aatatcaatg     1440

ttttaatcaa ggatctcttc cacattcctc cttcttataa gagcacagta acactatcct     1500

ggaaacctgt acaaaaggtt gagattgggc aaaagagagc cagtgaagat acaacttcag     1560

gttcaccacc caagaaatct tcagcaggac caaaaagaga tgccaggcag atttataacc     1620

ctcccagtgg gaaatatagc agcaatttgg gcaactttaa ttatgagcag agaggagcct     1680

tcaggggaag tagaggtggc cgaggttggg gcacacgagg aaatcgtagt cggggaagac     1740

tctactgaat aagacatcag cattcttcag cattgtcatg agcttaatat acttaaattc     1800

tactactcat tggattgccg gggatgtccc tttaaacaga ctgctgcctt cagctaaaaa     1860

cttaatgttc tttatacctt tgtatgtatg acctactttt gtaacagacc atggttgtgt     1920

ccaaggtaaa accacagtga tatttttgga tgctttgtct gcaatcttga cttgtttttg     1980

cagtatcatt attcagactt caaattgtga atcttttaaa catcttgata atttgttgtt     2040

gagagctgtt cattctaaaa tgtaatgaaa ttcagtctag ttctgctgat aaagatcatc     2100

agttttgaaa ggttactgat tttcctcttc cctcttagtt ttttacccaa tatatggaga     2160

agagtaatgg tcaatcttaa cattttgttt taattgttta ataaagctgc tgggcagtgg     2220

tgcagcattc ctacctagtg tcataaaagc aaaatactta catagctttc ttaaaatata     2280

ggaatgacat tacattttta ggagaaagta agttgctttg caccgcctac ttaattcttt     2340

tccatatatt gtgatacaaa cttttgaata tggaatctta ctatttgaat agaaatgtgt     2400

atgtataata tacatacata cataagcata tatgtgtgtg tgtgtgtgta tatatatata     2460

tatgcatgct gtgaaacttg actacacaac ataaatcact ttttaaattc caggaacggg     2520

tagtctgaca cggtgattat ccttttgagg ctgaatccgt tattaacttg ttatttaggt     2580

ttttactccc agtagcaagg gattctaagt tagttgcact tacatgatta ttgttattta     2640

aaactaagaa taaaggctgc attttcaaag ataaattgga attgctgttg gtgaaataac     2700

aaccaaaata ctgaatctga tgtacataca ggtttctaca ggaagagatg gtataattta     2760

caatttggag atttaataac cagggctacc cagaaaaagt gacttgataa catggtacca     2820

ataagtaagg gatgctctct cggtttgctt ttgccacttt caagatttta acttctcagg     2880

ttattaatca aaattattgt ataagttagc caatagaatt tttaggttaa aacaacagat     2940

ggggggtttg tggagtgttt aatgtcatgg gcatttttag tagcatagac cctttgttct     3000

gcatttgaat gtttcgtata tttttgtttc acagttaatc ttccctcccc aagtttgcta     3060

ttcaaatcaa ctgcctgaat gacatttcta gtagtctgat gtatttttct gaggaatagt     3120

ttgtgattcc aatgcaggtg tcttcattac cattacctct acactgcaga agaagcaaaa     3180

ctcctttatt agaattactg cacatgtgta tggggaaaat agttctgaaa ggctagaatg     3240

atacaagtga gcaaaagttg gtcagcttgg ctatggagtg gtggcaataa tctctaaaca     3300

ttccaaaaga ccatgagctg aacctaaact cccttggaat ctgaacaaag gaatataaaa     3360

ttgccatttg aaaactgacc agctaatctg gacctcagag atagatcagc cagtggccca     3420

aagccatttc aagtacagaa attatagaga ctacagctaa ataaatttga acattaaata     3480

taattttacc actttttgtc tttataagca tatttgtaaa ctcagaactg agcagaagtg     3540

actttacttt ctcaagtttg atactgagtt gactgttccc ttatccctca cccttcccct     3600

tccctttcct aaggcaatag tgcacaactt aggttatttt tgcttccgaa tttgaatgaa     3660

aaacttaatg ccatggattt ttttcttttg caagacacct gtttatcatc ttgtttaaat     3720

gtaaatgtcc ccttatgctt ttgaaataaa tttccttttg taattttgaa aaaaaaaaaa     3780

aa                                                                    3782


<210>  2636
<211>  3109
<212>  DNA
<213>  homo sapiens

<400>  2636
atcccagtgg gtggcagctg gaggcggggc accctgaggg gcggggaagg actagggtgc       60

ggggaggggg ttgcaaaagg agccgagcgg cttctgctca atggcggaaa agccgccggt      120

gctctgacgg cctcgttccc ctagcagttg cgggggagtt tcctgccggc gcggctggag      180

tctctgattc tcagggttcg gtggttggaa gatgctccag agagacgagg ctgcggcgga      240

ggaggtggcg gcggccgaat cggcaacggc gctagggtgg agagaaggcg gcatcggcgg      300

cggcggcggc gtgaggggcc gggcggtgta aacagccccg gaggcggcgg tcgagacccc      360

gagggggaag cggcggctga gtcagggtcg cgcctccgtt ggaaacttgg gctgagtacc      420

gcggcgggcg cgagcgaggc gccctagaca tcttctccct cccttgcctc agatttattg      480

ctaaacatgg gtgcattttt ggataaaccc aaaactgaaa aacataatgc tcatggtgct      540

gggaatggtt tacgttatgg cctgagcagc atgcaaggat ggagagtgga aatggaagat      600

gcacacacag ctgttgtagg tattcctcac ggcttggaag actggtcatt ttttgcagtt      660

tatgatggtc atgctggatc ccgagtggca aattactgct caacacattt attagaacac      720

atcactacta acgaagactt tagggcagct ggaaaatcag gatctgctct tgagctttca      780

gtggaaaatg ttaagaatgg tatcagaact ggatttttga aaattgatga atacatgcgt      840

aacttttcag acctcagaaa cgggatggac aggagtggtt caactgcagt gggagttatg      900

atttcaccta agcatatcta ctttatcaac tgtggtgatt cacgtgctgt tctgtatagg      960

aatggacaag tctgcttttc tacccaggat cacaaacctt gcaatccaag ggaaaaggag     1020

cgaatccaaa atgcaggagg cagcgtgatg atacaacgtg ttaatggttc attagcagta     1080

tctcgtgctc tgggggacta tgattacaag tgtgttgatg gcaagggccc aacagaacaa     1140

cttgtttctc cagagcctga ggtttatgaa attttaagag cagaagagga tgaatttatc     1200

atcttggctt gtgatgggat ctgggatgtt atgagtaatg aggagctctg tgaatatgtt     1260

aaatctaggc ttgaggtatc tgatgacctg gaaaatgtgt gcaattgggt agtggacact     1320

tgtttacaca agggaagtcg agataacatg agtattgtac tagtttgctt ttcaaatgct     1380

cccaaggtct cagatgaagc ggtgaaaaaa gattcagagt tggataagca cttggaatca     1440

cgggttgaag agattatgga gaagtctggc gaggaaggaa tgcctgatct tgcccatgtc     1500

atgcgcatct tgtctgcaga aaatatccca aatttgcctc ctgggggagg tcttgctggc     1560

aagcgtaatg ttattgaagc tgtttatagt agactgaatc cacatagaga aagtgatggg     1620

cagaaatgat gaagaaactg ttctgatggc ctgcttttct gtccttttcc tactgcttta     1680

aacattgatt ttcttttgta ctaaatcata tagccaaata ttgtttaagt aagtcagttt     1740

taggaaatgc ttgtgttgct gttgaattat aaaagctgag taaatttcag attaaacttt     1800

aaatgactgt gaaataagac ataaactagt taatggtaat ttgcttaaaa tgacttgaga     1860

ttattattgg aagtttttat taattgatac aggtaagaat tgatatttaa taaaatgttc     1920

tcatgcttag actatattac ttttcggtag agaaattagt attttgctgt aatgtgttat     1980

gaaatacatg tgatatccta gtttgtctac tgacactggg gtcttgaatc ttaaaaaaag     2040

gcctccgatg aagcagagga aagtggatca cagggaaaat tggtggaagc tctcaggcaa     2100

atgagaatta atcatagggg aaactaccga caacttctgg aggagatgct gactagttac     2160

aggctagcta aagtagaggg agaagaaagc cctgctgaac cagctgccac agctacttct     2220

tcgaacagtg atgctggaaa cccagtgaca atgcaggaaa gccatactga atcagaaagt     2280

ggtcttgctg aattagacag ctctaatgaa gatgcaggga caaagatgag tggtgaaaaa     2340

atatgacttt cctttttggt aatatttttg tgatctttga tggtttttaa cctaggaagt     2400

gtaatgtatg catttatata actgttttgt tatttgaatc ttggaaaact agttttatta     2460

tattcagata gccttgtttt ttaaaaaggc ctttgcatac acctttatga gatagtgtaa     2520

aattgactat ttatagtact atggatttaa tgaaattata tgtcatttca cattgtatgc     2580

cagaaattag gctaccaatt atgaattaaa gtcagtagtt aaattaatac tagatagaat     2640

tagaaatttt gattagagag attatgctat attatggaaa aacttgttaa tgtagaatta     2700

tactgcttca tattatttta cctattagta cactcatagt tagctttgta ataaatttat     2760

gttttcttta ataattttag ttcttcaaag aatggctgat gctggcctgt aatttttctt     2820

tcaaggatga taatttgtgt gttgtttgat ttgtttatat tttacatctc tgtagtttta     2880

tttttagaag ttgtgagata ttggatgtgt ggctattttt cctttctctg tattctttat     2940

gaaacataac ttttgaaaaa cctatgtatt attcatacag ctttggtttg tatattctgt     3000

atagcctaac tacacacatc aaaatgtatg tcaaccaagt gtttagaatg aaattataag     3060

tgtttaagtc caaataaagc atgtgatgtg gaataatcta taaaaaaaa                 3109


<210>  2637
<211>  6628
<212>  DNA
<213>  homo sapiens

<400>  2637
ctcctcggtg caacctatat aaggctcaca gtctgcgctc ctggtacacg cgcttcaact       60

tcggttggtg tgtgtcgaag aaacctgact gcgccctgag gagaacagcg gagaaggtcc      120

accgagcctg gcgaaaggtc cgctgagcgg gctgtcgtcc ggagccactc cgggctgcgg      180

agcacccagt ggagaccgcg cctggctcag gtgtgggacc ccatccttcc tgtcttcgca      240

gaggagtcct cgcgtgaaat aagcgggttt tgaaaacaaa aaaaagaagg agtggaagag      300

ggggccagga tccaggcctc catccccaca gaagtgaagc tacagctggg aggtctcctc      360

ccaccccaac cgtcaccctg ggtcccgact gcccacctcc tcctcctccc cctcccccca      420

acaacaacaa caacaacaac tccaagcaca ccggccataa gagtgcgtgt gtccccaaca      480

tgaccgaacg aagaagggac gagctctctg aagagatcaa caacttaaga gagaaggtca      540

tgaagcagtc ggaggagaac aacaacctgc agagccaggt gcagaagctc acagaggaga      600

acaccaccct tcgagagcaa gtggaaccca cccctgagga tgaggatgat gacatcgagc      660

tccgcggtgc tgcagcagct gctgccccac cccctccaat agaggaagag tgcccagaag      720

acctcccaga gaagttcgat ggcaacccag acatgctggc tcctttcatg gcccagtgcc      780

agatcttcat ggaaaagagc accagggatt tctcagttga tcgtgtccgt gtctgcttcg      840

tgacaagcat gatgaccggc cgtgctgccc gttgggcctc agcaaagctg gagcgctccc      900

actacctgat gcacaactac ccagctttca tgatggaaat gaagcatgtc tttgaagacc      960

ctcagaggcg agaggttgcc aaacgcaaga tcagacgcct gcgccaaggc atggggtctg     1020

tcatcgacta ctccaatgct ttccagatga ttgcccagga cctggattgg aacgagcctg     1080

cgctgattga ccagtaccac gagggcctca gcgaccacat tcaggaggag ctctcccacc     1140

tcgaggtcgc caagtcgctg tctgctctga ttgggcagtg cattcacatt gagagaaggc     1200

tggccagggc tgctgcagct cgcaagccac gctcgccacc ccgggcgctg gtgttgcctc     1260

acattgcaag ccaccaccag gtagatccaa ccgagccggt gggaggtgcc cgcatgcgcc     1320

tgacgcagga agaaaaagaa agacgcagaa agctgaacct gtgcctctac tgtggaacag     1380

gaggtcacta cgctgacaat tgtcctgcca aggcctcaaa gtcttcgccg gcgggaaact     1440

ccccggcccc gctgtagagg gaccttcagc gaccgggcca gaaataataa ggtccccaca     1500

agatgatgcc tcatctccac acttgcaagt gatgctccag attcatcttc cgggcagaca     1560

caccctgttc gtccgagcca tgatcgattc tggtgcttct ggcaacttca ttgatcacga     1620

atatgttgct caaaatggaa ttcctctaag aatcaaggac tggccaatac ttgtggaagc     1680

aattgatggg cgccccatag catcgggccc agttgtccac gaaactcacg acctgatagt     1740

tgacctggga gatcaccgag aggtgctgtc atttgatgtg actcagtctc cattcttccc     1800

tgtcgtccta ggggttcgct ggctgagcac acatgatccc aatatcacat ggagcactcg     1860

atctatcgtc tttgattctg aatactgccg ctaccactgc cggatgtatt ctccaatacc     1920

accatcgctc ccaccaccag caccacaacc gccactctat tatccagtag atggatacag     1980

agtttaccaa ccagtgaggt attactatgt ccagaatgtg tacactccag tagatgagca     2040

cgtctaccca gatcaccgcc tggttgaccc tcacatagaa atgatacctg gagcacacag     2100

tattcccagt ggacatgtgt attcactgtc cgaacctgaa atggcagctc ttcgagattt     2160

tgtggcaaga aatgtaaaag atgggctaat tactccaacg attgcaccta atggagccca     2220

agttctccag gtgaagaggg ggtggaaact gcaagtttct tatgattgcc gagctccaaa     2280

caattttact atccagaatc agtatcctcg cctatctatt ccaaatttag aagaccaagc     2340

acacctggca acgtacactg aattcgtacc tcaaatacct ggataccaaa cataccccac     2400

atatgccgcg tacccgacct acccagtagg attcgcctgg tacccagtgg gacgagacgg     2460

acaaggaaga tcactatatg tacctgtgat gatcacttgg aatccacact ggtaccgcca     2520

gcctccggta ccacagtacc cgccgccaca gccgccgcct ccaccaccac caccgccgcc     2580

gcctccatct tacagtaccc tgtaaatacc tgtcatgtcc ttcaggatct ctgccctcaa     2640

aatttattcc tgttcagctt ctcaatcagt gactgtgtgc taaattttag gctactgtat     2700

cttcaggcca cctgaggcac atcctctctg aaacggctat ggaaggttag ggccactctg     2760

gactggcaca catcctaaag caccaaaaga ccttcaacat tttctgagag caacagagta     2820

tttgccaata aatgatctct catttttcca ccttgactgc caatctaact aaaataatta     2880

ataagtttac tttccagcca gtcctggaag tctgggtttt acctgccaaa acctccatca     2940

ccatctaaat tataggctgc caaatttgct gtttaacatt tacagagaag ctgatacaaa     3000

cgcaggaaat gctgatttct ttatggaggg ggagacgagg aggaggagga catgactttt     3060

cttgcggttt cggtaccctc tttttaaatc actggaggac tgaggcctta ttaaggaagc     3120

caaaattatc ggtgcagtgt ggaaaggctt ccgtgatcct ctcgctgcac ccttagaaac     3180

ttcaccgtct tcaaactcca tttccatggt tctgttaatt ctcaaggagc agcaactcga     3240

ctggttctcc caggagcagg aaaaaccctt gtgacatgaa acatctcagg cctgaaaaga     3300

aagtgctctc tcagatggac tcttgcatgt taagactatg tcttcacatc atggtgcaaa     3360

tcacatgtac ccaatgactc cggctttgac acaacacctt accatcatca tgccatgatg     3420

gcttccacaa agcattaaac ctggtaacca gagattactg gtggctccag cgttgttaga     3480

tgttcatgaa atgtgaccac ctctcaatca cctttgaggg ctaaagagta gcacatcaaa     3540

aggactccaa aatcccatac ccaactctta agagatttgt cctggtactt cagaaagaat     3600

tttcatgagt gttcttaatt ggctggaaaa gcaccagctg acgttttgga agaatctatc     3660

catgtgtctg cctccatatg catctgggca tttcatcttc agtcccctca ttagactgta     3720

gcattaggat gtgtggagag aggagaaatg atttagcacc cagattcaca ctcctatgcc     3780

tggaaggggg acatctttga agaagaggaa ttagggctgt ggacactgtc ttgaggatgt     3840

ggacttcctt agtgagctcc acattacttg atggtaacca cttcaaaagg atcagaatcc     3900

acgtaatgaa aaaggtccct ctagaggatg gagctgatgt gaagctgcca atggatgaaa     3960

agcctcagaa agcaactcaa aggactcaaa gcaacggaca acacaagagt tgtcttcagc     4020

ccagtgacac ctctgatgtc ccctggaagc tttgtgctaa cctgggactg cctgacttcc     4080

tttagcctgg tcccttgcta ctaccttgaa ctgttttatc taacctctct ttttctgttt     4140

aattctttgc tactgccatt gaccctgctg caggatttgt gtcattttcc tgcctggttg     4200

ctgagactcc attttgctgc cacacacaga gatgtaagag gcaggcttta attgccaaag     4260

cacagtttga gcagtagaaa acaacatggt gtatatctca aattgcctga catgaagagg     4320

agtctaacgg tgaagtttca cttttcatca gcatcatctt tcacatgttc attatcatct     4380

gctcttattc ttgcatgttt aaacacttaa aatttttagt ataattttta gtgtgttttg     4440

aagtggtgac taggctttca aaaacttcca ttgaattaca aagcactatc cagttcttat     4500

tgttaaacta agtaaaaatg ataagtaaca tagtgtaaaa tattccttta ctgtgaactt     4560

cttacaatgc tgtgaatgag aggctcctca gaactggagc atttgtataa taattcatcc     4620

tgttcatctt caattttaac atcatatata atttcaattc tatcaattgg gcctttaaaa     4680

atcatataaa aggatataaa atttgaaaag agaaacctaa ttggctattt aatccaaaac     4740

aacttttttt ttccttcaat ggaatcagaa agcttgtcaa tcactcatgt gttttagagt     4800

aattactttt aaaatggtgc atttgtgctt ctgaactatt ttgaagagtc acttctgttt     4860

acctcaagta tcaattcatc ctccatacat ttgaattcaa gttgtttttt tgtcaaattt     4920

acagttgtca attgatcttc aagctgcagg gtgcctagaa atgggccgtt gtctgtagcc     4980

ctggcatgtg cacacggaca tttgccacca ctgcaagcaa aagtctggag aagttcacca     5040

acgacaagaa cgattaggga aaatatgctg ctgtgggtta acaactcaga aagtccctga     5100

tccacatttg gctgtttact aaagcttgtg attaactttt tggcagtgtg tactatgctc     5160

tattgctata tatgctatct ataaatgtag atgttaagga taagtaattc taaatttatt     5220

attctatagt tttgaagttt ggttaagttt cctttcactc aattgattta ttttgttgtt     5280

aatcaaattt atgttaattg gatcctttaa attttttttg gcattttcca acaaaaatgg     5340

ctttattcat aagaaaggaa aaaaatcaat ggaatttgat atctaaagaa gttagaaagg     5400

gagcaaaata aaaaacataa aggagataga tgaattagta agcaaatcag tagtcgagtt     5460

tttcaaactg gcaaaattaa ttaattgact tttagcccaa atttacattg ttaattaaat     5520

caagaaggaa gaagatctaa gagctcccat tgataggcaa gcctagagag aactagctaa     5580

atttatcatg ctaggatatt gaaacacaga aagtttacat acatttatga agggtcaatt     5640

tagtttggac agtgaggtat ttgtcttagt ggaaaaaagg agaattagtc tgatcaaatc     5700

gtgaagtaat acagtgaact tgcaggtgca caaaataaga gggccacatc tatatggtgc     5760

agtctggaat tctgtttaag tttgtaggta cctcttggac ttctgaattg atccagttgt     5820

catccaccac agacatctca catcagatac agacagttcc aagattgaca acagagaaca     5880

acctgctgga aagacctggg cagaaatgga gagccctgcg ggaaccatgc tacattttca     5940

tctaaagaga gaatgcacat ctgatgagac tgaaagttct ttgttgtttt agattgtaga     6000

atggtattga attggtctgt ggaaaattgc attgctttta tttctttgtg taatcaagtt     6060

taagtaatag gggatatata atcataagca ttttagggtg ggagggacta ttaagtaatt     6120

ttaagtgggt ggggttattt agaatgttag aataatatta tgtattagat atcgctataa     6180

gtggacatgc gtacttactt gtaacccttt accctataat tgctatcctt aaagatttca     6240

aataaactcg gagggaactg cagggagacc aacttattta gagcgaattg gacatggata     6300

aaaaccccag tgggagaaag ttcaaaggtg attagattaa taatttaata gaggatgagt     6360

gacctctgat aaattactgc tagaatgaac ttgtcaatga tggatggtaa attttcatgg     6420

aagttataaa agtgataaat aaaaaccctt gcttttaccc ctgtcagtag ccctcctcct     6480

accactgaac cccattgccc ctacccctcc ttctaacttt attgctgtat tctcttcact     6540

ctatatttct ctctatttgc taatattgca ttgctgttac aataaaaatt caataaagat     6600

ttagtggtta agtgcaaaaa aaaaaaaa                                        6628


<210>  2638
<211>  3320
<212>  DNA
<213>  homo sapiens

<400>  2638
gcacgtccaa accccggggt cctcggccag gccagggggg cgggcgtgcg gcggggccgg       60

gccgggccgg gcgcgcccag cgggctccgg gcacacgccc ctcacctggg cgaggcccgg      120

tgcgcaggcg ctcagcgcgg gggcagcggc cgggcgctta agcccggcgc gggcaagagt      180

tggacagttc aggggccgcg ccgggccgag ctgtcgcccg cgccacctcc accgccgccg      240

ctgctaccgc caccgccacc gcctgggctg cagcagatcg cgggagaacg tctgcgcgaa      300

gccccggtgc agccctggcg ggaccgcagc aaccaccgga gcgtgagcaa cagcttcccg      360

gctggaggag ccactgcccc acgcgcccgc ggcccgcgcg ccgagatgtt ctacatttca      420

actccatcaa atattaaatt gatgtttatg ggctaacctg gaaaccgaaa aacagtttgt      480

ttcactacaa gaataagaaa atatgtccaa attcctgtca gctgacttat aaagggactt      540

ttagaacaca acccaatgca tgaggtactc cttaagccct gacaaccatc ttgaagatgg      600

aatcatgaat atggcaaatt ttctacgggg ctttgaagaa aaggggataa agaacgacag      660

gcctgaggac cagttgagca aagagaaaaa gaaaattctt ttctccttct gtgaggtgtg      720

caacatccag ctgaactctg cagcccaggc tcaggtgcat tccaacggca aatcccaccg      780

caaacgagtg aagcagctga gtgatgggca gcccccacca cccgcccagg ccagccccag      840

cagcaacagc agcacaggca gtacatgcca cactactacc cttcctgctc ttgtgcgcac      900

acctaccctg atgatgcagc cttcactgga tatcaaacca tttatgtctt ttccagtgga      960

cagtagttct gctgttgggc tctttccaaa ttttaacaca atggatcctg tgcaaaaagc     1020

ggttattaac catacatttg gagtatccat tcccccaaag aagaaacaag ttatttcttg     1080

taatgtctgt cagcttcgct ttaactcaga tagccaggcc gaggcccact acaaaggaag     1140

taaacatgcc aagaaggtca aagcactaga cgcaacgaaa aataaaccca aaatggttcc     1200

ttccaaggac agcgcaaagg ctaatcccag ctgctccatc actccaatca caggcaacaa     1260

ctctgacaaa tcagaagata aagggaagtt aaaagccagc agttccagtc agccatcaag     1320

ctctgaaagt ggctcatttc tcctcaaatc tggcacaaca cccctgccac ctggagcagc     1380

cacttctccc tccaagagca caaatggagc tcccggtact gttgttgaat cagaagaaga     1440

aaaagccaaa aaattacttt attgttcact atgcaaagtg gctgtgaact ccctgtcaca     1500

gctagaggca cacaacacag gatctaaaca caagaccatg gttgaagctc gtaatggggc     1560

tggtccaatt aaatcctatc ctagacctgg atcaagatta aagatgcaga atggcagtaa     1620

ggggtcagga ctacagaaca agacatttca ttgtgaaatc tgtgatgttc atgttaattc     1680

agaaattcaa ctcaaacagc acatttctag ccgaaggcat aaagatcgag ttgcagggaa     1740

accactgaag ccaaaataca gcccttacaa caaactccag cggagcccga gtattctagc     1800

agcaaaactt gcattccaga aagatatgat gaagcctttg gccccagcct tcctgtcctc     1860

acctctcgca gcggcggcag ccgtgtcctc agcgctgtca ctcccacccc ggccctctgc     1920

ctcgctcttc caggctccag ccattcctcc agctcttctg aggcctgggc atgggcccat     1980

ccgcgccact cctgcctcca tcctctttgc tccgtactaa cgtctgcaaa ccccaagacg     2040

tttgaggcca gtaggaagtt gagaaagaaa gccacaagga ttcagcaatt taagcagttt     2100

gtgttgcagt accccccatt cacccacaaa atgcagccca ccacccagtc ccccaattcc     2160

agagagaaac acatcactag attgacgagg gcttttagag actgctccta taattgagga     2220

atcagcagca taggctttat ctccctactt cctcccccac cctaccgcgt tcaatttgtg     2280

tatctcagat atttgatttc ttgagcatgt attggtcaga aagaaaaaga aagaaaacca     2340

ttctctattt ttccatgggt atgatctggc ttaaaacaat atggaatatt ttcctgacag     2400

acttgaaaac taggatcttc ctcagatgtc tgtaaataac tctggtatcc aactgggtgt     2460

attctagtgt ggaacaaaaa acagtgaaca caagtgctta cttgtggata ctatcttacc     2520

aacggatcac aaagttctct ttttggtgta ctgttgttga cagggattgt gtactgtttc     2580

gacccaagta ctgctgtatc ctgtgtagta ctagatctgt atctcttgtc tgaattaaac     2640

atttttagtt gctgtgtaaa tgttaggaag caaagtagct ttgaattttc tctgtaagag     2700

aataaaagat aaaataatgt attttcttta tttcacattt tatttggaga tatttaaatg     2760

aaatagaaag ccatataaca tagctataat tactacctgt ttgctatttt tgtttaactt     2820

attttgtagc ttcctcactg gtttgtgttg ctaagcaaac gtatacaaac agaaaaagag     2880

cttcctaaat tgcacatttt tgcacctctt gtgcattctg caagaagaca atgaatccat     2940

gtatttctat ataagtatct tcttcatttt taacctgttt tcatttgtaa tgatgctaca     3000

taattttgtg gctccctaat gcaataatgt acagaagata aaaaaattta taattgaaca     3060

atttgtcttt ctgttcgctg aatatattgc aggtcatgct cccatgcccc cctttctaag     3120

ccgatatcaa caagactgga atgtttgtga tatcaggggc aagagttatc atagaacaac     3180

aaaatagagt ggactctttt agagcatcta tatctgcaac ctgtaaatgg taaaatgtct     3240

gtgtattttt ttaaatgtac cttttcaata aaagtacaaa aaataaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa                                                 3320


<210>  2639
<211>  1665
<212>  DNA
<213>  homo sapiens

<400>  2639
gctcagcatt tggggacgct ctcagctctc ggcgcacggc ccagggtgaa aatgtttgcc       60

attaaactca catgaagtag gaaatattta tatggataca aaaggcacct gcatgggata      120

atgtcaaatt tcatagatac tgctttgtgc ttccttcaaa atgtctactg ttcacgaaat      180

cctgtgcaag ctcagcttgg agggtgatca ctctacaccc ccaagtgcat atgggtctgt      240

caaagcctat actaactttg atgctgagcg ggatgctttg aacattgaaa cagccatcaa      300

gaccaaaggt gtggatgagg tcaccattgt caacattttg accaaccgca gcaatgcaca      360

gagacaggat attgccttcg cctaccagag aaggaccaaa aaggaacttg catcagcact      420

gaagtcagcc ttatctggcc acctggagac ggtgattttg ggcctattga agacacctgc      480

tcagtatgac gcttctgagc taaaagcttc catgaagggg ctgggaaccg acgaggactc      540

tctcattgag atcatctgct ccagaaccaa ccaggagctg caggaaatta acagagtcta      600

caaggaaatg tacaagactg atctggagaa ggacattatt tcggacacat ctggtgactt      660

ccgcaagctg atggttgccc tggcaaaggg tagaagagca gaggatggct ctgtcattga      720

ttatgaactg attgaccaag atgctcggga tctctatgac gctggagtga agaggaaagg      780

aactgatgtt cccaagtgga tcagcatcat gaccgagcgg agcgtgcccc acctccagaa      840

agtatttgat aggtacaaga gttacagccc ttatgacatg ttggaaagca tcaggaaaga      900

ggttaaagga gacctggaaa atgctttcct gaacctggtt cagtgcattc agaacaagcc      960

cctgtatttt gctgatcggc tgtatgactc catgaagggc aaggggacgc gagataaggt     1020

cctgatcaga atcatggtct cccgcagtga agtggacatg ttgaaaatta ggtctgaatt     1080

caagagaaag tacggcaagt ccctgtacta ttatatccag caagacacta agggcgacta     1140

ccagaaagcg ctgctgtacc tgtgtggtgg agatgactga agcccgacac ggcctgagcg     1200

tccagaaatg gtgctcacca tgcttccagc taacaggtct agaaaaccag cttgcgaata     1260

acagtccccg tggccatccc tgtgagggtg acgttagcat tacccccaac ctcattttag     1320

ttgcctaagc attgcctggc cttcctgtct agtctctcct gtaagccaaa gaaatgaaca     1380

ttccaaggag ttggaagtga agtctatgat gtgaaacact ttgcctcctg tgtactgtgt     1440

cataaacaga tgaataaact gaatttgtac tttagaaaca cgtactttgt ggccctgctt     1500

tcaactgaat tgtttgaaaa ttaaacgtgc ttggggttca gctggtgagg ctgtccctgt     1560

aggaagaaag ctctgggact gagctgtaca gtatggttgc ccctatccaa gtgtcgctat     1620

ttaagttaaa tttaaatgaa ataaaataaa ataaaatcaa aaaaa                     1665


<210>  2640
<211>  1682
<212>  DNA
<213>  homo sapiens

<400>  2640
gcaggaccgt cattgacgcc atgagcgcgc tgctgcggct gctgcgcacg ggtgccccag       60

ccgctgcgtg cctgcggttg gggaccagtg cagggaccgg gtcgcgccgt gctatggccc      120

tgtaccacac tgaggagcgc ggccagccct gctcgcagaa ttaccgcctc ttctttaaga      180

atgtaactgg tcactacatt tccccctttc atgatattcc tctgaaggtg aactctaaag      240

aggaaaatgg cattcctatg aagaaagcac gaaatgatga atatgagaat ctgtttaata      300

tgattgtaga aatacctcgg tggacaaatg ctaaaatgga gattgccacc aaggagccaa      360

tgaatcccat taaacaatat gtaaaggatg gaaagctacg ctatgtggcg aatatcttcc      420

cttacaaggg ttatatatgg aattatggta ccctccctca gacttgggaa gatccccatg      480

aaaaagataa gagcacgaac tgctttggag ataatgatcc tattgatgtt tgcgaaatag      540

gctcaaagat tctttcttgt ggagaagtta ttcatgtgaa gatccttgga attttggctc      600

ttattgatga aggtgaaaca gattggaaat taattgctat caatgcgaat gatcctgaag      660

cctcaaagtt tcatgatatt gatgatgtta agaagttcaa accgggttac ctggaagcta      720

ctcttaattg gtttagatta tataaggtac cagatggaaa accagaaaac cagtttgctt      780

ttaatggaga attcaaaaac aaggcttttg ctcttgaagt tattaaatcc actcatcaat      840

gttggaaagc attgcttatg aagaagtgta atggaggagc tataaattgc acaaacgtgc      900

agatatctga tagccctttc cgttgcactc aagaggaagc aagatcatta gttgaatcgg      960

tatcatcttc accaaataaa gaaagtaatg aagaagagca agtgtggcac ttccttggca     1020

agtgattgaa acatctgaaa ttctgctgtc aagattccca tctctaagga ctccaagtgc     1080

tagagacaag ggggtctatg agcatttact gacttcctgt taaaacttca ttttttcaaa     1140

ctttttgagc tatgcaatat ataaataaac agtaagaatt ttaaattact ctcctttgga     1200

catttattga tataaaaaga agattttggc caggcacggt ggctcatgcc tgtaatttca     1260

gcactttggg aggccgaggt gggcagatca caaggtcagg agttcaagac cagcctggcc     1320

agtatgttga aaccccatct ctattaaaaa tacaaaaatt agccaggcgt ggtggtgcat     1380

gcctgtagac ccagctactc aggaggctga ggcagaagaa ctgcttgagc ccaggaggca     1440

gaggttgcag tgagcagaga ttgtgccact gcactccagc ctaggcgaca gagagagact     1500

ccgtctcaaa aaaaaaaaaa agattttgtt tcatttcata gcacaaattt agaggcattg     1560

agttgaccat ttctagtttc tatacctgaa ggaacccatt gattttacca gtttttattt     1620

ctgtagattg gatgtaaaaa tcacagattc aataaattaa taaactttgt gtaaaaaaaa     1680

aa                                                                    1682


<210>  2641
<211>  2304
<212>  DNA
<213>  homo sapiens

<400>  2641
aactgagttc aaggcaatta aagtcaagag ctaaggaggg agggagaggg tttagaaata       60

ccagcataat aagtagtatg actgggtgct ctgtaaatta actcaattag acaaagcctg      120

acttaacggg ggaagatggt gagaagcgct accctcatta aatttggttg ttagaggcgc      180

ttctaaggaa attaagtctg ttagttgttt gaatcacata aaattgtgtg tgcacgttca      240

tgtacacatg tgcacacatg taacctctgt gattcttgtg ggtatttttt taagaagaaa      300

ggaatagaaa gcaaagaaaa ataaaaaata ctgaaaagaa aagactgaaa gagtagaaga      360

taaggagaaa agtacgacag agacaaggaa agtaagagag agagagagct ctcccaatta      420

taaagccatg agcccccttt ggtgggggtt tctgctcagt tgcttgggct gcaaaatcct      480

gccaggagcc cagggtcagt tcccccgagt ctgcatgacg gtggacagcc tagtgaacaa      540

ggagtgctgc ccacgcctgg gtgcagagtc ggccaatgtc tgtggctctc agcaaggccg      600

ggggcagtgc acagaggtgc gagccgacac aaggccctgg agtggtccct acatcctacg      660

aaaccaggat gaccgtgagc tgtggccaag aaaattcttc caccggacct gcaagtgcac      720

aggaaacttt gccggctata attgtggaga ctgcaagttt ggctggaccg gtcccaactg      780

cgagcggaag aaaccaccag tgattcggca gaacatccat tccttgagtc ctcaggaaag      840

agagcagttc ttgggcgcct tagatctcgc gaagaagaga gtacaccccg actacgtgat      900

caccacacaa cactggctgg gcctgcttgg gcccaatgga acccagccgc agtttgccaa      960

ctgcagtgtt tatgattttt ttgtgtggct ccattattat tctgttagag atacattatt     1020

aggaccagga cgcccctaca gggccataga tttctcacat caaggacctg catttgttac     1080

ctggcaccgg taccatttgt tgtgtctgga aagagatctc cagcgactca ttggcaatga     1140

gtcttttgct ttgccctact ggaactttgc cactgggagg aacgagtgtg atgtgtgtac     1200

agaccagctg tttggggcag cgagaccaga cgatccgact ctgattagtc ggaactcaag     1260

attctccagc tgggaaactg tctgtgatag cttggatgac tacaaccacc tggtcacctt     1320

gtgcaatgga acctatgaag gtttgctgag aagaaatcaa atgggaagaa acagcatgaa     1380

attgccaacc ttaaaagaca tacgagattg cctgtctctc cagaagtttg acaatcctcc     1440

cttcttccag aactctacct tcagtttcag gaatgctttg gaagggtttg ataaagcaga     1500

tgggactctg gattctcaag tgatgagcct tcataatttg gttcattcct tcctgaacgg     1560

gacaaacgct ttgccacatt cagccgccaa tgatcccatt tttgtggttc ttcattcctt     1620

tactgatgcc atctttgatg agtggatgaa aagatttaat cctcctgcag atgcctggcc     1680

tcaggagctg gcccctattg gtcacaatcg gatgtacaac atggttcctt tcttccctcc     1740

agtgactaat gaagaactct ttttaacctc agaccaactt ggctacagct atgccatcga     1800

tctgccagtt tcagttgaag aaactccagg ttggcccaca actctcttag tagtcatggg     1860

aacactggtg gctttggttg gtctttttgt gctgttggct tttcttcaat atagaagact     1920

tcgaaaagga tatacacccc taatggagac acatttaagc agcaagagat acacagaaga     1980

agcctagggt gctcatgcct tacctaagag aagaggctgg ccaagccaca gttctgacgc     2040

tgacaataaa ggaactaatc ctcactgttc cttcttgagt tgaagatctt tgacataggt     2100

tcttctatag tgatgatgat ctcattcaga agatgcttag ctgtagtttc cgctttgctt     2160

gcttgtttaa caaacccaac taaagtgctt gaggctacct ctaccttcaa ataaagatag     2220

acctgacaat ttgtgatatc taataataac ccccccccca atattgatta agcctcctcc     2280

ttttctgaaa gcatttaaaa aaaa                                            2304


<210>  2642
<211>  10138
<212>  DNA
<213>  homo sapiens

<400>  2642
gcacgggctg gtctctgccc taatgcggcg gctggcggcg agaggcgctg caggggacgc       60

gggggaagtg gcggcgccgg cagcggacag ctcggacagc gcccagggcc ggagcccgag      120

cccttggagg ttgattgact tatgtgcaat ttgggacgct ggagtttacc ttccctccgc      180

agcctggaac agagcctcct ctggtgttgc aaggaagagg ctgaatgagg cagagaagct      240

gagtgctgtc caggaggccc agttaaagcg gctcgaggtg acaagacccc gagtgctggg      300

gagcagggag cagggccagg tgccgaggat ggccaggcag ccaccgccgc cctgggtcca      360

tgcagccttc ctcctctgcc tcctcagtct tggcggagcc atcgaaattc ctatggatct      420

gacgcagccg ccaaccatca ccaagcagtc agcgaaggat cacatcgtgg acccccgtga      480

taacatcctg attgagtgtg aagcaaaagg gaaccctgcc cccagcttcc actggacacg      540

aaacagcaga ttcttcaaca tcgccaagga cccccgggtg tccatgagga ggaggtctgg      600

gaccctggtg attgacttcc gcagtggcgg gcggccggag gaatatgagg gggaatatca      660

gtgcttcgcc cgcaacaaat ttggcacggc cctgtccaat aggatccgcc tgcaggtgtc      720

taaatctcct ctgtggccca aggaaaacct agaccctgtc gtggtccaag agggcgctcc      780

tttgacgctc cagtgcaacc ccccgcctgg acttccatcc ccggtcatct tctggatgag      840

cagctccatg gagcccatca cccaagacaa acgtgtctct cagggccata acggagacct      900

atacttctcc aacgtgatgc tgcaggacat gcagaccgac tacagttgta acgcccgctt      960

ccacttcacc cacaccatcc agcagaagaa ccctttcacc ctcaaggtcc tcaccaacca     1020

cccttataat gactcgtcct taagaaacca ccctgacatg tacagtgccc gaggagttgc     1080

agaaagaaca ccaagcttca tgtatcccca gggcaccgcg agcagccaga tggtgcttcg     1140

tggcatggac ctcctgctgg aatgcatcgc ctccggggtc ccaacaccag acatcgcatg     1200

gtacaagaaa ggtggggacc tcccatctga taaggccaag tttgagaact ttaataaggc     1260

cctgcgtatc acaaatgtct ctgaggaaga ctccggggag tatttctgcc tggcctccaa     1320

caagatgggc agcatccggc acacgatctc ggtgagagta aaggctgctc cctactggct     1380

ggacgaaccc aagaacctta ttctggctcc tggcgaggat gggagactgg tgtgtcgagc     1440

caatggaaac cccaaaccca ctgtccagtg gatggtgaat ggggaacctt tgcaatcggc     1500

accacctaac ccaaaccgtg aggtggccgg agacaccatc atcttccggg acacccagat     1560

cagcagcagg gctgtgtacc agtgcaacac ctccaacgag catggctacc tgctggccaa     1620

cgcctttgtc agtgtgctgg atgtgccgcc tcggatgctg tcgccccgga accagctcat     1680

tcgagtgatt ctttacaacc ggacgcggct ggactgccct ttctttgggt ctcccatccc     1740

cacactgcga tggtttaaga atgggcaagg aagcaacctg gatggtggca actaccatgt     1800

ttatgagaac ggcagtctgg aaattaagat gatccgcaaa gaggaccagg gcatctacac     1860

ctgtgtcgcc accaacatcc tgggcaaagc tgaaaaccaa gtccgcctgg aggtcaaaga     1920

ccccaccagg atctaccgga tgcccgagga ccaggtggcc agaaggggca ccacggtgca     1980

gctggagtgt cgggtgaagc acgacccctc cctgaaactc accgtctcct ggctgaagga     2040

tgacgagccg ctctatattg gaaacaggat gaagaaggaa gacgactccc tgaccatctt     2100

tggggtggca gagcgggacc agggcagtta cacgtgtgtc gccagcaccg agctagacca     2160

agacctggcc aaggcctacc tcaccgtgct aggacggcca gaccggcccc gggacctgga     2220

gctgaccgac ctggccgaga ggagcgtgcg gctgacctgg atccccgggg atgctaacaa     2280

cagccccatc acagactacg tcgtccagtt tgaagaagac cagttccaac ctggggtctg     2340

gcatgaccat tccaagtacc ccggcagcgt taactcagcc gtcctccggc tgtccccgta     2400

tgtcaactac cagttccgtg tcattgccat caacgaggtt gggagcagcc accccagcct     2460

cccatccgag cgctaccgaa ccagtggagc accccccgag tccaatcctg gtgacgtgaa     2520

gggagagggg accagaaaga acaacatgga gatcacgtgg acgcccatga atgccacctc     2580

ggcctttggc cccaacctgc gctacattgt caagtggagg cggagagaga ctcgagaggc     2640

ctggaacaac gtcacagtgt ggggctctcg ctacgtggtg gggcagaccc cagtctacgt     2700

gccctatgag atccgagtcc aggctgaaaa tgacttcggg aagggccctg agccagagtc     2760

cgtcatcggt tactccggag aagattatcc cagggctgcg cccactgaag ttaaagtccg     2820

agtcatgaac agcacagcca tcagccttca gtggaaccgc gtctactccg acacggtcca     2880

gggccagctc agagagtacc gagcctacta ctggagggag agcagcttgc tgaagaacct     2940

gtgggtgtct cagaagagac agcaagccag cttccctggt gaccgcctcc gtggcgtggt     3000

gtcccgcctc ttcccctaca gtaactacaa gctggagatg gttgtggtca atgggagagg     3060

tgatgggcct cgcagtgaga ccaaggagtt caccaccccg gaaggagtac ccagtgcccc     3120

taggcgtttc cgagtccggc agcccaacct ggagacaatc aacctggaat gggatcatcc     3180

tgagcatcca aatgggatca tgattggata cactctcaaa tatgtggcct ttaacgggac     3240

caaagtagga aagcagatag tggaaaactt ctctcccaat cagaccaagt tcacggtgca     3300

aagaacggac cccgtgtcac gctaccgctt taccctcagc gccaggacgc aggtgggctc     3360

tggggaagcc gtcacagagg agtcaccagc acccccgaat gaagcttaca ccaacaacca     3420

agcggacatc gccacccagg gctggttcat tgggcttatg tgcgccatcg ccctcctggt     3480

gctgatcctg ctcatcgtct gtttcatcaa gaggagtcgc ggcggcaagt acccagtacg     3540

agaaaagaag gatgttcccc ttggccctga agaccccaag gaagaggatg gctcatttga     3600

ctatagtgat gaggacaaca agcccctgca gggcagtcag acatctctgg acggcaccat     3660

caagcagcag gagagtgacg acagcctggt ggactatggc gagggtggcg agggtcagtt     3720

caatgaagac ggctccttca tcggccagta cacggtcaaa aaggacaagg aggaaacaga     3780

gggcaacgaa agctcagagg ccacgtcacc tgtcaatgct atctactctc tggcctaacg     3840

gagcccaccc aggcacagcc accactttgc aagtgggagg aggggagaag gggagacaaa     3900

accactgcag acctaccacg aagccaccac caccttcagt aacaagggta cgatatgggg     3960

gtctgccaag ctgtgaggac cagtagccac caagccaccc acaagccccc tcccaatgac     4020

cccccttcag ccccgggtgc caccagtgtg ggagagctgg agccgtggct gagctcagct     4080

ggagggagcc tggccccttg cccggtctcg cagccacccc gagcgttcca ccacactgtc     4140

cgcccttggc ctcggcacac gctcaccttt tctgttggtt acgggacttc tcattgtctt     4200

aatttcgctt tgtgcatctt cccctccaga cccaatgtct ctgttttctt ttccttttga     4260

aaaagagtcc ctggaaaaga aagaataagt ggattctccc ccaggagaat cctttttgca     4320

aagataggca aaaaggattg aatccatacc agaacacgta gacaggctgt aatattcaaa     4380

ccacctctgg gccaatgcat ttccaaagga tgcctttctc gccatatgcc tcccctggcc     4440

cccagcccct ctgcctcggc cttgtcagtt gctgagctgg gcttggctcc tttctggaaa     4500

atgacagtat ttttggcagg gagaaggtgc gcaggcctcc ttgctgctct ctggtttggt     4560

tgggaggtgt gtttacctct tgctcctcat tcctcccctg cccttttctc tggaatatct     4620

aagatgtgag ctgcattgac tctgaagacg tttgaggaac aggagtgggc actgatagaa     4680

aggacttcaa cgccagtgac tgtgtacctc cagcagaaga aaatcaggtg tctggtcttg     4740

ggggcactgt gctcacttct agagagaaga aaaaggctgg gtttggactt catgcctcct     4800

cactggtgaa acccaggatg tagatagagg gccacaccca ccctgtccag agtagagggc     4860

acctgtccac gtggccaggg cccatgctgc caccctcgag gagatggaac cctgtgatgc     4920

aaaagctttg ctggtgtgtt tggggcataa ggcactgctc cccttccatc tctagcagat     4980

atcatcttct cagccaattc tgtaggacac tgaggctctt gtttgacatg gtgtgtggat     5040

ggggacttgc cccaagactg agcaggtctg ccctttcatt ggggtgtata catatcaggg     5100

gaccctgagg tggcaccgta ctcagtgttg tgatgccccc acctagggag gactcaatgc     5160

tctttgtatg ccttatgcag cgctgatctg tccctggagt tcccaggttc ccagctcccc     5220

ccctgcaagc cttgaagcct ccagcaacgt ctatctccag gagagcaggg cagcctatgc     5280

aagtgttccg gcaggaccag aagtggccac tcaacacacg tcctcaccag tcaccccaaa     5340

tggagacact cgcagacctg cagttctcag accgaaggtg ctgccttcat cctccccacc     5400

taatgcattt ttgaaaccaa aggtacctag cctcagagac agagaaggag agggggagat     5460

cttgagtcta agaggaaccc tttagctgtt tctgcagctg aggtcagttt caggagggtg     5520

aagctgatcc ccaggaatgg atcagctgcc atgggcacag cctccgattt gagcctctcc     5580

ggctgccagc cagggggcct gggccagacc agggctctgt ccttccgtga ctttattaaa     5640

gcaacatttg ccacatgttt aagccgcaaa ggtattagca atgcttgcat cattaataat     5700

cattcagttg aaggtcaagc ccatagacac acactctctg ctggtaagaa accatagccc     5760

agaactgagc caataaggtt gtttgaacct gagagtgtgt aatggtcatt tgggccaagc     5820

ctcagctagg gctgctgcct ggacgcctga ggggcagctt atcacagtgc aaggggacag     5880

ggtaaacagc agggggtggg gtgtgagctt ggagggcccc tcccctggat ttcctccaac     5940

acctgcttgg atactaggcc cactgtccct gaagggaatg tcagggaagt gtgcctgtga     6000

gctgaattaa aggactggcc tttccagaaa acgctttgga tctgagcaga gtagtcagtt     6060

tctcagacac tcattccata ctgcaccgta catgccagcg tacccattgc accgaaagca     6120

ggcccttagg gcaggaaggg acgatgagca agtctgccac accacctggt gactgggaag     6180

ggctgcttct ctcgtaaggg tcttggggag aagtaagccc gcagcctgcc tctgcacctc     6240

gttccagtgt cctgccaggc tctgtactgt cctttgtgta tgaagaaaat gctgttagcc     6300

ctctctcagg ctgctgttct gtgggtgctg agagctgccc cccatcacca cgccatcaca     6360

cccctctgag cagaagcaaa tctgaggctg aagaattaag ttttccccaa gcaaggaagg     6420

caggtggtca gagagatcaa acgctgaggc gtggggattg caggattcag gaggcagccc     6480

ctttggggaa gaggagggtg cattttccat ggagcccatg tcagagtcca ctccagctca     6540

gcaggaaagt ggaattgccc agtactgcct gccagctggg tctcccaagc aactacccca     6600

agacatacca acagtgaagc caggacagca ccatgccatc ggcgctccag tctgtctggc     6660

tgggaggaaa gtgctgggca tcttacagta actctagaag ttcctttgac taggctgcaa     6720

tcccacctat atgctcagcc ctaagagctg tggtttcctg tgctctcatt tgtccattca     6780

ttcattcatt cattcattca gcaaataatc tgaaatccag tctgaactaa ggcctgagct     6840

gtggatacca tggcgcgtga gttagatgtg gtccctgccc tcatggggct gacagtccta     6900

aaatcaagtg ctaggacaca gtggccattg agctgggagc attcttccct ctaccgctta     6960

agccactgat ggctgcgagc ttgaagagag ggattctgag ggagagcttg gtccatctgg     7020

tcaccaaggc tgggcgggac agagcagtca agaaccacgg tgtggcttga gaaacagtcc     7080

tgcttcctga gcctctttgc tctgcctctt ggggcaagct ccttaacctg tctgtatttt     7140

tatgcctctg tctcccattc agttcctcct tgaatacctc tttctacaga gaggcacggg     7200

ctcccctgaa ggattgtcga ggccagggtt cgggaagtac actgccatcg gtcaggggac     7260

agctgcctcc caccttgcct gggtgatggt gaatgggact catcttttcc tgccttgctt     7320

ttgaggagat ggttgaattt aagctaacag gaaagccaaa ccagcaccct cctttgtgct     7380

ctgagaggtt ggagacatct ggtccacccc attgcccctg cccctggcaa gccctgaagt     7440

cgggagaggt gaccacaggt ctgaaaatca gccagtgcca acattgcttg ccctgcaagg     7500

tgcaactgag cccacatagc gcattcatag tttccctgac cacagccttg ggaagacggt     7560

ggaaacccga ggatgtgtgg gtttcccagc taacggacaa gctcccctgc cacacccagt     7620

gcccacgcat gctcacatac atacagcaga ccacaaccct gttgccaagc agtgcttcca     7680

agggatagcg atccagattc caacattgtc ttggagaggg ttagtccaca tccaagttgc     7740

gtgagataag atgcaaaggg ctctgtgtgg atgaggaacg caccttagag gagtgggaaa     7800

ggccaccagg gttgggccct gtttaggtaa ttcctgttgg cagcacctag agagagcatc     7860

tgagctgaag gagtgggaaa ctttgcccaa gcaatggcac gggcagcggg ctctttctgg     7920

cgccctgtgc tggagcaggg ccaagtctta gggcatcaca aacagcccat ttgatggagg     7980

gagcagggac atagcacatt tttgtctgtc tttgtgaggc tgctttgcta actctctgag     8040

gagaggaagc ctctcgggct ttccgtcggc tggggctagt gccagagaat cccttctcag     8100

tggccagcag gttcctggga ggccggcaca aggcaccgct ccccactcat gacaccttgg     8160

tgcagagtga cctcctgccc agtcaccact ccggccagcc ccagccaaac acacaaaagc     8220

ccatggttgc ggttgcatct acaccgttag ttggcaaagg atcctgcttg agctctgcgt     8280

ggtggccaag gagtagcatg gaggagggcc ctgattttaa aaaggaaaaa tagagaggcc     8340

tcaaaacaat gaaacaaaga gcttgatatg tcaagaggag accaaggccc tgggaggcat     8400

aggcaagccg ggcagagtca gaccagtgcc ctcccttgac catctcctag cattccttaa     8460

cctagacagg ggctacccca tgtgagtcca agccagactt tgtggctgtc cccagcctgc     8520

acagcccaag cccagggaag tgtcctttct ttcccttcct tactaataat gggccttcct     8580

gagacacatt cagagaagga tcagagagaa aggagaacca tccaggagag ccacaagcgt     8640

ccaccaaaca gtgtctcagg cctcacctga agctgctgtt cctcctatca gcacactagt     8700

attaaatggg tgttccataa tgaggagaat ggaaataggt acaaggcatc tagcttagga     8760

cagaatcgga tttcggcatg tgaaggaatc ccagagctga tctcattgaa atgatctatc     8820

gtacagacaa ggatatgcaa atccacagaa gtgaagggat ttttgctcaa gatcacatag     8880

ctggtaaact aaggtaaggt tagggcttga acttgggcct tctgactcct tgtccagtca     8940

gtgttctttc atctcaccac agctgcctcc tttgaaacag aggtattaag atctgtcctt     9000

ctggttcacc ctctcatacc tctttactgc gtctcccaca tcccccacat gcctcccaaa     9060

atgaaagaca aacaggattg tttctgagac caagatcagt ctgtctgtga tcagcctgtg     9120

tgtggttcac ccagtcatgc aattaagggc agatctgggc cagtggaata ggatagctga     9180

ttggtgtttg ttactgtgaa ccctagaccg taccccgtag aatggtgtct cttgctttgt     9240

aacacatcgg gccttcagtg tgctgtattc ctcagaagtg agggcatctc ggtccattct     9300

gcccatggcc acagggtgca gagaggcagc agggcccatg caagctgcca ccctgggatt     9360

tgctgggctg gagttcaaca gatgtaaaga cttcagtgaa gcaataaaca caaaactctg     9420

ggagaagata tccagaattt tgtacattac tctgtttctt tttcaaaaat gaggcagatc     9480

agatgcccct gagctgcccc tttttttctg attcccaact gcaatgtcct cagtcagtgt     9540

tgtccctctg cccggctccc cagctctttg ccaacctctt cacactcccc ttgagctgag     9600

catcagtcgc ctgtgacgtg gccaccttct gtcctgctcc cactcccgac ccatgctgga     9660

ccccggagga cctcctgccc cgcccccacc acacacccat atcccccacc attccaattt     9720

gttctttccc gtggggaatt ttttttccca gcgtctccat cccttcctac atatccacac     9780

acacacaaat tggtctgatc ttttttccat tggttaaaca tttaactcca tgccagacct     9840

tgttttaacc cctctcacat catgttcttt ccttttttgc gagttatttt gcattaacca     9900

actttgtcag tgacagatgc gtatctgagg gtgtcacaca cgaccttcag cagggaagac     9960

ttctgggcca tggagggccg tctaatacat ggacttataa actgactgca tgagcaatga    10020

aaaggccaaa ttattctgaa ttttttttga atcactgtaa aaaaactgat ttcttttgta    10080

tagagaacac taaacgtata ataaaagttg ttcaaaatgg aaaaaaaaaa aaaaaaaa      10138


<210>  2643
<211>  9141
<212>  DNA
<213>  homo sapiens

<400>  2643
accatagagt gaatctcaga acaggaagcg gaggcataag cagagaggat tctggaaagg       60

tctctttgtt ttcttatcca cagagaaaga aagaaaaaaa attgtaacta atttgtaaac      120

ctctgtggtc aaaaaaaaaa aaaaaaaaaa aagctgaaca gctgcagagg aagacacgtt      180

ataccctaac catcttggat gctgggcttt gttatgctgt aattcataag gctctgtttt      240

atcagagatt atggagcaag aaaactgaag ccaagccaca tcaaggtttg acagggatga      300

gatacctgtc aaggattcat agtagagtgg cttactggga aaggagcaaa gaatctcttc      360

tagggatatt gtaagaataa atgagataat tcacagaagg gacctggagc ttttccggaa      420

aaaggtgctg tgactatcta aggtaattcg tatgcaagaa gctacacgta attaaatgtg      480

caggatgaaa agatggcaca ggcactgttg gtacccccag gacctgaaag cttccgcctt      540

tttactagag aatctcttgc tgctatcgaa aaacgtgctg cagaagagaa agccaagaag      600

cccaaaaagg aacaagataa tgatgatgag aacaaaccaa agccaaatag tgacttggaa      660

gctggaaaga accttccatt tatttatgga gacattcctc cagagatggt gtcagagccc      720

ctggaggacc tggatcccta ctatatcaat aagaaaactt ttatagtaat gaataaagga      780

aaggcaattt tccgattcag tgccacctct gccttgtata ttttaactcc actaaaccct      840

gttaggaaaa ttgctatcaa gattttggta cattctttat tcagcatgct tatcatgtgc      900

actattttga ccaactgtgt atttatgacc ttgagcaacc ctcctgactg gacaaagaat      960

gtagagtaca cattcactgg aatctatacc tttgagtcac ttataaaaat cttggcaaga     1020

gggttttgct tagaagattt tacgtttctt cgtgatccat ggaactggct ggatttcagt     1080

gtcattgtga tggcatatgt gacagagttt gtggacctgg gcaatgtctc agcgttgaga     1140

acattcagag ttctccgagc actgaaaaca atttcagtca ttccaggttt aaagaccatt     1200

gtgggggccc tgatccagtc ggtaaagaag ctttctgatg tgatgatcct gactgtgttc     1260

tgtctgagcg tgtttgctct cattgggctg cagctgttca tgggcaatct gaggaataaa     1320

tgtttgcagt ggcccccaag cgattctgct tttgaaacca acaccacttc ctactttaat     1380

ggcacaatgg attcaaatgg gacatttgtt aatgtaacaa tgagcacatt taactggaag     1440

gattacattg gagatgacag tcacttttat gttttggatg ggcaaaaaga ccctttactc     1500

tgtggaaatg gctcagatgc aggccagtgt ccagaaggat acatctgtgt gaaggctggt     1560

cgaaacccca actatggcta cacaagcttt gacaccttta gctgggcttt cctgtctcta     1620

tttcgactca tgactcaaga ctactgggaa aatctttacc agttgacatt acgtgctgct     1680

gggaaaacat acatgatatt ttttgtcctg gtcattttct tgggctcatt ttatttggtg     1740

aatttgatcc tggctgtggt ggccatggcc tatgaggagc agaatcaggc caccttggaa     1800

gaagcagaac aaaaagaggc cgaatttcag cagatgctcg aacagcttaa aaagcaacag     1860

gaagaagctc aggcagttgc ggcagcatca gctgcttcaa gagatttcag tggaataggt     1920

gggttaggag agctgttgga aagttcttca gaagcatcaa agttgagttc caaaagtgct     1980

aaagaatgga ggaaccgaag gaagaaaaga agacagagag agcaccttga aggaaacaac     2040

aaaggagaga gagacagctt tcccaaatcc gaatctgaag acagcgtcaa aagaagcagc     2100

ttccttttct ccatggatgg aaacagactg accagtgaca aaaaattctg ctcccctcat     2160

cagtctctct tgagtatccg tggctccctg ttttccccaa gacgcaatag caaaacaagc     2220

attttcagtt tcagaggtcg ggcaaaggat gttggatctg aaaatgactt tgctgatgat     2280

gaacacagca catttgaaga cagcgaaagc aggagagact cactgtttgt gccgcacaga     2340

catggagagc gacgcaacag taacgttagt caggccagta tgtcatccag gatggtgcca     2400

gggcttccag caaatgggaa gatgcacagc actgtggatt gcaatggtgt ggtttccttg     2460

gtgggtggac cttcagctct aacgtcacct actggacaac ttcccccaga gggcaccacc     2520

acagaaacgg aagtcagaaa gagaaggtta agctcttacc agatttcaat ggagatgctg     2580

gaggattcct ctggaaggca aagagccgtg agcatagcca gcattctgac caacacaatg     2640

gaagaacttg aagaatctag acagaaatgt ccgccatgct ggtatagatt tgccaatgtg     2700

ttcttgatct gggactgctg tgatgcatgg ttaaaagtaa aacatcttgt gaatttaatt     2760

gttatggatc catttgttga tcttgccatc actatttgca ttgtcttaaa taccctcttt     2820

atggccatgg agcactaccc catgactgag caattcagta gtgtgttgac tgtaggaaac     2880

ctggtcttta ctgggatttt cacagcagaa atggttctca agatcattgc catggatcct     2940

tattactatt tccaagaagg ctggaatatc tttgatggaa ttattgtcag cctcagttta     3000

atggagcttg gtctgtcaaa tgtggaggga ttgtctgtac tgcgatcatt cagactgctt     3060

agagttttca agttggcaaa atcctggccc acactaaata tgctaattaa gatcattggc     3120

aattctgtgg gggctctagg aaacctcacc ttggtgttgg ccatcatcgt cttcattttt     3180

gctgtggtcg gcatgcagct ctttggtaag agctacaaag aatgtgtctg caagatcaat     3240

gatgactgta cgctcccacg gtggcacatg aacgacttct tccactcctt cctgattgtg     3300

ttccgcgtgc tgtgtggaga gtggatagag accatgtggg actgtatgga ggtcgctggc     3360

caaaccatgt gccttattgt tttcatgttg gtcatggtca ttggaaacct tgtggttctg     3420

aacctctttc tggccttatt gttgagttca tttagctcag acaaccttgc tgctactgat     3480

gatgacaatg aaatgaataa tctgcagatt gcagtaggaa gaatgcaaaa gggaattgat     3540

tatgtgaaaa ataagatgcg ggagtgtttc caaaaagcct tttttagaaa gccaaaagtt     3600

atagaaatcc atgaaggcaa taagatagac agctgcatgt ccaataatac tggaattgaa     3660

ataagcaaag agcttaatta tcttagagat gggaatggaa ccaccagtgg tgtaggtact     3720

ggaagcagtg ttgaaaaata cgtaatcgat gaaaatgatt atatgtcatt cataaacaac     3780

cccagcctca ccgtcacagt gccaattgct gttggagagt ctgactttga aaacttaaat     3840

actgaagagt tcagcagtga gtcagaacta gaagaaagca aagagaaatt aaatgcaacc     3900

agctcatctg aaggaagcac agttgatgtt gttctacccc gagaaggtga acaagctgaa     3960

actgaacccg aagaagacct taaaccggaa gcttgtttta ctgaaggatg tattaaaaag     4020

tttccattct gtcaagtaag tacagaagaa ggcaaaggga agatctggtg gaatcttcga     4080

aaaacctgct acagtattgt tgagcacaac tggtttgaga ctttcattgt gttcatgatc     4140

cttctcagta gtggtgcatt ggcctttgaa gatatataca ttgaacagcg aaagactatc     4200

aaaaccatgc tagaatatgc tgacaaagtc tttacctata tattcattct ggaaatgctt     4260

ctcaaatggg ttgcttatgg atttcaaaca tatttcacta atgcctggtg ctggctagat     4320

ttcttgatcg ttgatgtttc tttggttagc ctggtagcca atgctcttgg ctactcagaa     4380

ctcggtgcca tcaaatcatt acggacatta agagctttaa gacctctaag agccttatcc     4440

cggtttgaag gcatgagggt ggttgtgaat gctcttgttg gagcaattcc ctctatcatg     4500

aatgtgctgt tggtctgtct catcttctgg ttgatcttta gcatcatggg tgtgaatttg     4560

tttgctggca agttctacca ctgtgttaac atgacaacgg gtaacatgtt tgacattagt     4620

gatgttaaca atttgagtga ctgtcaggct cttggcaagc aagctcggtg gaaaaacgtg     4680

aaagtaaact ttgataatgt tggcgctggc tatcttgcac tgcttcaagt ggccacattt     4740

aaaggctgga tggatattat gtatgcagct gttgattcac gagatgttaa acttcagcct     4800

gtatatgaag aaaatctgta catgtattta tactttgtca tctttatcat ctttgggtca     4860

ttcttcactc tgaatctatt cattggtgtc atcatagata acttcaacca gcagaaaaag     4920

aagtttggag gtcaagacat ctttatgaca gaggaacaga aaaaatatta caatgcaatg     4980

aagaaacttg gatccaagaa acctcagaaa cccatacctc gcccagcaaa caaattccaa     5040

ggaatggtct ttgattttgt aaccagacaa gtctttgata tcagcatcat gatcctcatc     5100

tgcctcaaca tggtcaccat gatggtggaa acggatgacc agggcaaata catgacccta     5160

gttttgtccc ggatcaacct agtgttcatt gttctgttca ctggagaatt tgtgctgaag     5220

ctcgtctccc tcagacacta ctacttcact ataggctgga acatctttga ctttgtggtg     5280

gtgattctct ccattgtagg tatgtttctg gctgagatga tagaaaagta ttttgtgtcc     5340

cctaccttgt tccgagtgat ccgtcttgcc aggattggcc gaatcctacg tctgatcaaa     5400

ggagcaaagg ggatccgcac gctgctcttt gctttgatga tgtcccttcc tgcgttgttt     5460

aacatcggcc tcctgctctt cctggtcatg tttatctatg ccatctttgg gatgtccaac     5520

tttgcctatg ttaaaaagga agctggaatt gatgacatgt tcaactttga gacctttggc     5580

aacagcatga tctgcttgtt ccaaattaca acctctgctg gctgggatgg attgctagca     5640

cctattctta atagtgcacc acccgactgt gaccctgaca caattcaccc tggcagctca     5700

gttaagggag actgtgggaa cccatctgtt gggattttct tttttgtcag ttacatcatc     5760

atatccttcc tggttgtggt gaacatgtac atcgcggtca tcctggagaa cttcagtgtt     5820

gctactgaag aaagtgcaga gcccctgagt gaggatgact ttgagatgtt ctatgaggtt     5880

tgggaaaagt ttgatcccga tgcgacccag tttatagagt tctctaaact ctctgatttt     5940

gcagctgccc tggatcctcc tcttctcata gcaaaaccca acaaagtcca gcttattgcc     6000

atggatctgc ccatggtcag tggtgaccgg atccactgtc ttgatatttt atttgccttt     6060

acaaagcgtg ttttgggtga gagtggagag atggatgccc ttcgaataca gatggaagac     6120

aggtttatgg catcaaaccc ctccaaagtc tcttatgagc ctattacaac cactttgaaa     6180

cgtaaacaag aggaggtgtc tgccgctatc attcagcgta atttcagatg ttatctttta     6240

aagcaaaggt taaaaaatat atcaagtaac tataacaaag aggcaattaa agggaggatt     6300

gacttaccta taaaacaaga catgattatt gacaaactaa atgggaactc cactccagaa     6360

aaaacagatg ggagttcctc taccacctct cctccttcct atgatagtgt aacaaaacca     6420

gacaaggaaa agtttgagaa agacaaacca gaaaaagaaa gcaaaggaaa agaggtcaga     6480

gaaaatcaaa agtaaaaaga aacaaagaat tatctttgtg atcaattgtt tacagcctat     6540

gaaggtaaag tatatgtgtc aactggactt caagaggagg tccatgccaa actgactgtt     6600

ttaacaaata ctcatagtca gtgcctatac aagacagtga agtgacctct ctgtcactgc     6660

aactctgtga agcagggtat caacattgac aagaggttgc tgtttttatt accagctgac     6720

actgctgagg agaaacccaa tggctaccta gactataggg atagttgtgc aaagtgaaca     6780

ttgtaactac accaaacacc tttagtacag tccttgcatc cattctattt ttaacttcca     6840

tatctgccat atttttacaa aatttgttct agtgcatttc catggtcccc aattcatagt     6900

ttattcataa tgctatgtca ctatttttgt aaatgaggtt tacgttgaag aaacagtata     6960

caagaaccct gtctctcaaa tgatcagaca aaggtgtttt gccagagaga taaaattttt     7020

gctcaaaacc agaaaaagaa ttgtaatggc tacagtttca gttacttcca ttttctagat     7080

ggctttaatt ttgaaagtat tttagtctgt tatgtttgtt tctatctgaa cagttatgtg     7140

cctgtaaagt ctcctctaat atttaaagga ttatttttat gcaaagtatt ctgtttcagc     7200

aagtgcaaat tttattctaa gtttcagagc tctatattta atttaggtca aatgctttcc     7260

aaaaagtaat ctaataaatc cattctagaa aaatatatct aaagtattgc tttagaatag     7320

ttgttccact ttctgctgca gtattgcttt gccatcttct gctctcagca aagctgatag     7380

tctatgtcaa ttaaataccc tatgttatgt aaatagttat tttatcctgt ggtgcatgtt     7440

tgggcaaata tatatatagc ctgataaaca acttctatta aatcaaatat gtaccacagt     7500

gtatgtgtct tttgcaagct tccaacaggg atgtatcctg tatcattcat taaacatagt     7560

ttaaaggcta tcactaatgc atgttaatat tgcctatgct gctctatttt actcaatcca     7620

ttcttcacaa gtcttggtta aagaatgtca catattggtg atagaatgaa ttcaacctgc     7680

tctgtccatt atgtcaagca gaataatttg aagctattta caaacacctt tacttttgca     7740

cttttaattc aacatgagta tcatatggta tctctctaga tttcaaggaa acacactgga     7800

tactgcctac tgacaaaacc tattcttcat attttgctaa aaatatgtct aaaacttgtt     7860

taaatataaa taatgtaaaa atataatcaa ctttatttgt cagcattttg tacataagaa     7920

aattattttc aggttgatga catcacaatt tattttactt tatgcttttg cttttgattt     7980

ttaatcacaa ttccaaactt ttgaatccat aagatttttc aatggataat ttcctaaaat     8040

aaaagttaga taatgggttt tatggatttc tttgttataa tatattttct accattccaa     8100

taggagatac attggtcaaa cactcaaacc tagatcattt tctaccaact atggttgcct     8160

caatataacc ttttattcat agatgttttt ttttattcaa cttttgtagt atttacgtat     8220

gcagactagt cttatttttt taattcctgc tgcactaaag ctattacaaa tataacatgg     8280

actttgttct ttttagccat gaacaaagtg gcaaagttgt gcaattacct aacatgatat     8340

aaatttttgt tttttgcaca aaccaaaagt ttaatgttaa ttctttttac aaaactattt     8400

actgtagtgt attgaagaac tgcatgcagg gaattgctat tgctaaaaag aatggtgagc     8460

tacgtcatta ttgagccaaa agaataaatt tcatttttta ttgcatttca cttattggcc     8520

tctggggttt tttgtttttg ttttttgctg ttggcagttt aaaatatata taattaataa     8580

aacctgtgct tgatctgaca tttgtataca taaaagttta catgaatttt acaacaaact     8640

agtgcatgat tcaccaagca gtactacaga acaaaggcaa attaaaagca gctttgtgaa     8700

cttttatgtg tgcaaaggat caagttcaca tgttccaact ttcaggtttg ataataatag     8760

tagtaaccac ctacaatagc tttcaatttc aattaactcc cttggctata agcatctaaa     8820

ctcatcttct ttcaatataa ttgatgctat ctcctaatta cttggtggct aataaatgtt     8880

acattctttg ttacttaaat gcattatata aactcctatg tatacataag gtattaatga     8940

tatagttatt gagaatttat attaactttt ttttcaagaa cccttggatt tatgtgaggt     9000

caaaaccaaa ctcttattct cagtggaaaa ctccagttgt aatgcatatt tttaaagaca     9060

atttggatct aaatatgtat ttcataattc tcccataata aattatataa ggtggctaat     9120

tggaaaaaaa aaaaaaaaaa a                                               9141


<210>  2644
<211>  935
<212>  DNA
<213>  homo sapiens

<400>  2644
agtcagaggt cgcgcaggcg ctggtacccc gttggtccgc gcgttgctgc gttgtgaggg       60

gtgtcagctc agtgcatccc aggcagctct tagtgtggag cagtgaactg tgtgtggttc      120

cttctacttg gggatcatgc agagagcttc acgtctgaag agagagctgc acatgttagc      180

cacagagcca cccccaggca tcacatgttg gcaagataaa gaccaaatgg atgacctgcg      240

agctcaaata ttaggtggag ccaacacacc ttatgagaaa ggtgttttta agctagaagt      300

tatcattcct gagaggtacc catttgaacc tcctcagatc cgatttctca ctccaattta      360

tcatccaaac attgattctg ctggaaggat ttgtctggat gttctcaaat tgccaccaaa      420

aggtgcttgg agaccatccc tcaacatcgc aactgtgttg acctctattc agctgctcat      480

gtcagaaccc aaccctgatg acccgctcat ggctgacata tcctcagaat ttaaatataa      540

taagccagcc ttcctcaaga atgccagaca gtggacagag aagcatgcaa gacagaaaca      600

aaaggctgat gaggaagaga tgcttgataa tctaccagag gctggtgact ccagagtaca      660

caactcaaca cagaaaagga aggccagtca gctagtaggc atagaaaaga aatttcatcc      720

tgatgtttag gggacttgtc ctggttcatc ttagttaatg tgttctttgc caaggtgatc      780

taagttgcct accttgaatt tttttttaaa tatatttgat gacataattt ttgtgtagtt      840

tatttatctt gtacatatgt attttgaaat cttttaaacc tgaaaaataa atagtcattt      900

aatgttgaaa aaaaaaaaaa aaaaaaaaaa aaaaa                                 935


<210>  2645
<211>  2775
<212>  DNA
<213>  homo sapiens

<400>  2645
gttgggaaag agcagcctgg gcggcagggg cggtggctgg agctcggtaa agctcgtggg       60

accccattgg gggaatttga tccaaggaag cggtgattgc cgggggagga gaagctccca      120

gatccttgtg tccacttgca gcgggggagg cggagacggc ggagcgggcc ttttggcgtc      180

cactgcgcgg ctgcaccctg ccccatcctg ccgggatcat ggtctgcggc agcccgggag      240

ggatgctgct gctgcgggcc gggctgcttg ccctggctgc tctctgcctg ctccgggtgc      300

ccggggctcg ggctgcagcc tgtgagcccg tccgcatccc cctgtgcaag tccctgccct      360

ggaacatgac taagatgccc aaccacctgc accacagcac tcaggccaac gccatcctgg      420

ccatcgagca gttcgaaggt ctgctgggca cccactgcag ccccgatctg ctcttcttcc      480

tctgtgccat gtacgcgccc atctgcacca ttgacttcca gcacgagccc atcaagccct      540

gtaagtctgt gtgcgagcgg gcccggcagg gctgtgagcc catactcatc aagtaccgcc      600

actcgtggcc ggagaacctg gcctgcgagg agctgccagt gtacgacagg ggcgtgtgca      660

tctctcccga ggccatcgtt actgcggacg gagctgattt tcctatggat tctagtaacg      720

gaaactgtag aggggcaagc agtgaacgct gtaaatgtaa gcctattaga gctacacaga      780

agacctattt ccggaacaat tacaactatg tcattcgggc taaagttaaa gagataaaga      840

ctaagtgcca tgatgtgact gcagtagtgg aggtgaagga gattctaaag tcctctctgg      900

taaacattcc acgggacact gtcaacctct ataccagctc tggctgcctc tgccctccac      960

ttaatgttaa tgaggaatat atcatcatgg gctatgaaga tgaggaacgt tccagattac     1020

tcttggtgga aggctctata gctgagaagt ggaaggatcg actcggtaaa aaagttaagc     1080

gctgggatat gaagcttcgt catcttggac tcagtaaaag tgattctagc aatagtgatt     1140

ccactcagag tcagaagtct ggcaggaact cgaacccccg gcaagcacgc aactaaatcc     1200

cgaaatacaa aaagtaacac agtggacttc ctattaagac ttacttgcat tgctggacta     1260

gcaaaggaaa attgcactat tgcacatcat attctattgt ttactataaa aatcatgtga     1320

taactgatta ttacttctgt ttctcttttg gtttctgctt ctctcttctc tcaacccctt     1380

tgtaatggtt tgggggcaga ctcttaagta tattgtgagt tttctatttc actaatcatg     1440

agaaaaactg ttcttttgca ataataataa attaaacatg ctgttaccag agcctctttg     1500

ctggagtctc cagatgttaa tttactttct gcaccccaat tgggaatgca atattggatg     1560

aaaagagagg tttctggtat tcacagaaag ctagatatgc cttaaaacat actctgccga     1620

tctaattaca gccttatttt tgtatgcctt ttgggcattc tcctcatgct tagaaagttc     1680

caaatgttta taaaggtaaa atggcagttt gaagtcaaat gtcacatagg caaagcaatc     1740

aagcaccagg aagtgtttat gaggaaacaa cacccaagat gaattatttt tgagactgtc     1800

aggaagtaaa ataaatagga gcttaagaaa gaacattttg cctgattgag aagcacaact     1860

gaaaccagta gccgctgggg tgttaatggt agcattcttc ttttggcaat acatttgatt     1920

tgttcatgaa tatattaatc agcattagag aaatgaatta taactagaca tctgctgtta     1980

tcaccatagt tttgtttaat ttgcttcctt ttaaataaac ccattggtga aagtcttttt     2040

ttttctcttc ttttaaaata aatcagaatt gccgtattga ccaggaaaag attatgtatg     2100

cacgtgcacc agggttagtt tttaaaagta catggctcca taaaaatgct gtagattaca     2160

gagtgataaa atatgcaggt ttttttgttt ttgttttttc tgttgtgtgt gtgtctgtat     2220

ttgtgtacat gtgtgtcctt gcactcacac ccaaggtgga ttaaaataca ggcctgcaaa     2280

ctggcctgca ctttatcatt tggatttgtg ctgcttaatg ctcagcgaaa aatgtctagt     2340

aaaatgaatt atggttgtca ggagagaggt tatttcgact tttgaaccaa ttgcacattt     2400

ctcattaccc aagctgtggt gagatcccag gggctgtggt gaacaaatga tgcttttata     2460

gatggtccct agcttacaat gattcaattt acaatgcttc aatttaacaa tttgttgact     2520

tacaatgggt ttatcaggat gtaacccaat gcatttcaac ttacgatatt ttcagtttcg     2580

aatgggttta tccagatgta accccatcgt aaatggcgga gcatctgtac ttccttcctc     2640

tggcagagtt ccttagagcc tgtgccaatt acttgaaagt ttcattctct gccatttaca     2700

tgtgtgctat tagtagaacc aaatttctaa gctgtggcgt gctgaaaata aaatgcttat     2760

gaagcaaaaa aaaaa                                                      2775


<210>  2646
<211>  5880
<212>  DNA
<213>  homo sapiens

<400>  2646
gaagtcagcg ctgagtccca gaaaaacaga gcggggccag ctgcagcgtg tagtgcgagt       60

ggggcggacg cgcgcagccc gcccgcccgg cgaccagcaa ggagttggca tcctttggaa      120

gagttcgtga aagctttctg cccagagctc ctggaccaat gcatcttccc accaccttaa      180

accactgagc agttcagagc cccagttgca gacgacttgt cctgccacca ccatgagttc      240

tgaatgtgat ggtggttcca aagctgtgat gaatggcttg gcacctggca gcaatgggca      300

agacaaagca actgccgacc ctttacgcgc acgctctatt tctgctgtta aaatcattcc      360

tgtgaagaca gtgaaaaacg cctcaggcct agttctccct acagacatgg atcctacaaa      420

aatctgcact gggaagggag cggtgactct ccgggcctcg tcttcctaca gggaaacccc      480

aagcagtagc cctgcgagcc ctcaggaaac ccggcaacac gaaagcaaac caggtctgga      540

gccagagcct tcttcagcag atgagtggag gctttcttcc agtgctgatg ccaatggaaa      600

tgcccagccc tcttcactcg ctgccaaggg ctacagaagt gtgcatccca accttccttc      660

tgacaagtcc caggattcca gtcctctact aaatgaagtt tcttcttccc ttattggaac      720

tgattcccaa gcctttccat cagttagcaa gccttcatcc gcctatccct ccacaacgat      780

tgtcaatcct actattgtgc tcttgcaaca caatcgagaa cagcaaaaac gactcagtag      840

cctttcagat cctgtctcag aaagaagagt gggagagcag gactcagcac caacccagga      900

aaaacccacc tcacctggca aggctattga aaaaagagca aaggatgaca gtaggcgggt      960

ggtgaagagc actcaggact taagcgatgt ttccatggat gaagtgggca tcccactccg     1020

gaacactgag agatcaaaag actggtacaa gactatgttt aaacagatcc acaaactgaa     1080

cagagatgat gattcagatc tgtactctcc cagatactca ttttctgaag acacaaaatc     1140

tcccctttct gtgcctcgct caaaaagtga gatgagctac attgatggtg agaaggtagt     1200

caagaggtcg gccacactac ccctcccagc ccgctcttcc tcactgaagt caagctcaga     1260

aagaaatgac tgggaacccc cagataagaa agtagacaca agaaaatatc gtgcagagcc     1320

caagagcatt tacgaatatc agcctggcaa gtcttccgtt ctgaccaacg aaaagatgag     1380

ctcagccatc agccctactc cggaaatttc ttcagagact cctggatata tatattcttc     1440

caacttccat gcagtgaaga gggaatcaga cggggctcct ggggatctca ctagcttgga     1500

gaatgagaga caaatttata aaagtgtctt ggaaggtggt gacatccctc ttcagggcct     1560

gagtgggctc aagcgaccat ccagctctgc ttccactaaa gattcagaat cgccaagaca     1620

ttttatacca gctgattact tggaatccac ggaagaattt attcgaagac gtcatgatga     1680

taaagagaaa cttttagcgg accagagacg acttaaacgc gagcaagaag aggctgatat     1740

tgcagctcga cgccacacag gcgtcattcc gacgcaccat cagtttatca ctaatgagcg     1800

ctttggggac ctcctcaata tagacgatac tgcaaaaagg aaatctgggt cagagatgag     1860

acctgccaga gccaaatttg actttaaagc tcagacacta aaggagcttc ctctgcagaa     1920

gggagatatt gtttacattt ataagcaaat tgatcagaac tggtatgaag gagaacacca     1980

cggccgggtg ggaatcttcc cacgcaccta catcgagctt cttcctcctg ctgagaaggc     2040

acagcccaaa aagttgacac cagtgcaggt tttggaatat ggagaagcta ttgctaagtt     2100

taactttaat ggtgatacac aagtagaaat gtccttcaga aagggtgaga ggatcacact     2160

gctccggcag gtagatgaga actggtacga agggaggatc ccggggacat cccgacaagg     2220

catcttcccc atcacctacg tggatgtgat caagcgacca ctggtgaaaa accctgtgga     2280

ttacatggac ctgcctttct cctcctcccc aagtcgcagt gccactgcaa gcccacagca     2340

acctcaagcc cagcagcgaa gagtcacccc cgacaggagt caaacctcac aagatttatt     2400

tagctatcaa gcattatata gctatatacc acagaatgat gatgagttgg aactccgcga     2460

tggagatatc gttgatgtca tggaaaaatg tgacgatgga tggtttgttg gtacttcaag     2520

aaggacaaag cagtttggta cttttccagg caactatgta aaacctttgt atctataaga     2580

agactgaaaa ccatggagat tatttttatt ggaggaggaa gcatcattca tgaaccgatc     2640

tttttagttg agtcagtagg aaaattaata cagtggataa agtaagaagc aaaagacagg     2700

gacagagaag tgttgtgttt aaaacccaag cctgtctaag gttactgtgt attagacagg     2760

gccgaactag tgtgctgagc aaaaagaatt gaagcaaatt gtatttactt agccgcttct     2820

gggagccact tcagcctttc ccctcccctc cacttcttgg gtaatctgac ctgaagcata     2880

gtccaggagc agagttagcc agaaatgcct cctgctgccc cagccttaga gagctcccat     2940

ctcaatcatt gagcctgaag gcttcaagcc caagaatgca acaagacccc cagcctacat     3000

ttctcagctc ccctggagcc agctgatcct gtaacgctgc tggaggtcag tctgagctac     3060

caagactgtc cctagacaaa ggtggagtcc cccacactgc ccaagaccaa atccctcact     3120

caacctgctg aggtgtggat ggggaaacag aggcaaaact gaggcacctg atgcattcag     3180

cctgctgtgc agcagtgcca ttgactgccc tgatgttcag agagaaacgc acacaaggtt     3240

tgcccatgag aattggggag cagatggcca agcagatagg ttatgtctgt tttctgagtg     3300

atgaagtcag gaagccctgt ggctctggag gccacttgtg gttcattctt ttcccatatc     3360

cttggctttt agaaatggtt accttcagga cagtgcagct gcatttatca gagcactatt     3420

gctaagtttt cttttctggc ttgtgttttt ctgggacagt ttagaattgg gaggcctatt     3480

ctcatagaac accaaaaatg atgttcagtg attcatttaa catacaccaa tgtactctgg     3540

ctgctggggg gacaaccata agcaagacat gcccagggtt tgccgtggct ccagatctac     3600

tccctgtagg agttcaagga tcacacaaac ggtagtaacc agggttgtga atctgagtac     3660

accctggcaa ggcttctctt cagactgaag cagcaattct gccactacca gcagcaacca     3720

ggacgtctgt tctttgtggg ggccagatca gaagagagag gcccctgtga cgcccgggct     3780

gcttggtcac aactctgtcc aattcaagga tgtttatcgg cctctcttag atcctgagtg     3840

agacaaatac agaaatgacc cattccctgc ccaccagaaa ctcagaggtg attggggaga     3900

ctgacacagg aaaatgaact taatcaagag agactgtgat atgtgctaag aagggtgtga     3960

gggagggaga gatgaatttt ccctggaggg atcctagaaa gcattgtcat attgccatct     4020

ccattagctc acttttaaac aactagggtg ctggaagaac ctttgtctga gggtagttca     4080

tagctggaaa tacttggaat attttccaga gtctctaaac tctcatcttc ccccacagat     4140

acacatccaa gctcacaaat aggagtagca attctaggtg gtagggttgt gtacggaacc     4200

cctggctgtc tgcatatatc tcagaattac cccaggacca ttgtcccaaa gtctagagtc     4260

tttacaggta ggcaaaattt gttttcaatg cctgtgcctc agctgctgtc acaaataccc     4320

atcttaggat cccatcagct tcccatcccc caccagacag ccacagtacc ctcactttct     4380

ccctattgtt ctttcaaatc ctgttctcag gaaagaaact gccactaatt cattcacact     4440

aaggtgtaaa tgattgataa taggaatgag ttacctcttc ccacagacat ttgtttttaa     4500

gtatgacaga gcagggcctt aatcccaagg gaaaaggtta tggaactgga gggggtgagc     4560

tttctgggta gaaggagact tcctgaattt ccttaaaacc cagtaagagt aagacctgtt     4620

gttttggaag gtctgctcca ccatctaaga gcactgtttt tttttttttg ttgttgttgt     4680

tgttttacgg tctctgaggg aatatagtaa aaatgcatat gcacgtgcaa tttgcacggc     4740

agcatttcac cgattgtgga ctgtattggc taatgtgttt cctggtcttt agatgcaaac     4800

cattaataac actatcttat ctcatagttt tttcaggggt gcttcttgat tagtagggaa     4860

ttttgaacac ctctttaaat acagctagaa aataaaacca atttgtaaag ccacatttgc     4920

atatgatgcc agcctcacgc atttgtatat ctccagaaat tcaggtatgc ctcaccaatt     4980

tgcccgtctt taataaaatc ttgtgttaaa atttgcatca cgtcgccttc ctatgtatga     5040

cgaaacaaga aacagagatt tccaattgct cttttgtctt cagacattta gtaatataaa     5100

gtacctattt ttatgctgaa atgtttatac aggtttatta atagcaagtg caactaactg     5160

gcggcatgcc ttgcaacaca ttttgatata ttagccatgc ttccgggtaa aggcaagccc     5220

caaactcctt atcttttgca gtctctctgg gatcagtaaa agaaaaaaaa aataatgtgc     5280

ttaagaagtg ggactgtaaa tatgtatatt taactttgta tagcccatgt acctaccttg     5340

tatagaaaaa taattttaaa aatttgaatg gaagggggta aaggaagtca tgaagttttt     5400

ttgcattttt atttaaatga aggaattcca aataactcac ctacagattt ttagcacaaa     5460

aatagccatt gtaaagtgtt aaaatttacg ataagtattc tattggggag gaaaggtaac     5520

tctgatctca gttacagttt ttttttcctt tttaatttca ttattttggg tttttggttt     5580

ttgcagtcct atttatctgc agtcgtatta agtcctattg ctagaatagg ttactacaaa     5640

aaaggttata ttctgaaaga aaaataactg acattatata taaccaatta atttaaagta     5700

ttgccattta aattacacac tgagagcatg tcctatgcag acatagattt ttctgttcat     5760

ttatttttct tcattgcagt ggattgattt gataaataga tgtgttgaat tactacattt     5820

gctgtacata ttatttaata aactttattc agaattgcgt ggcaaaaaaa aaaaaaaaaa     5880


<210>  2647
<211>  6574
<212>  DNA
<213>  homo sapiens

<400>  2647
aagagcaaaa agcgaaggcg caatctggac actgggagat tcggagcgca gggagtttga       60

gagaaacttt tattttgaag agaccaaggt tgaggggggg cttatttcct gacagctatt      120

tacttagagc aaatgattag ttttagaagg atggactata acattgaatc aattacaaaa      180

cgcggttttt gagcccatta ctgttggagc tacagggaga gaaacagagg aggagactgc      240

aagagatcat tggaggccgt gggcacgctc tttactccat gtgtgggaca ttcattgcgg      300

aataacatcg gaggagaagt ttcccagagc tatggggact tcccatccgg cgttcctggt      360

cttaggctgt cttctcacag ggctgagcct aatcctctgc cagctttcat taccctctat      420

ccttccaaat gaaaatgaaa aggttgtgca gctgaattca tccttttctc tgagatgctt      480

tggggagagt gaagtgagct ggcagtaccc catgtctgaa gaagagagct ccgatgtgga      540

aatcagaaat gaagaaaaca acagcggcct ttttgtgacg gtcttggaag tgagcagtgc      600

ctcggcggcc cacacagggt tgtacacttg ctattacaac cacactcaga cagaagagaa      660

tgagcttgaa ggcaggcaca tttacatcta tgtgccagac ccagatgtag cctttgtacc      720

tctaggaatg acggattatt tagtcatcgt ggaggatgat gattctgcca ttataccttg      780

tcgcacaact gatcccgaga ctcctgtaac cttacacaac agtgaggggg tggtacctgc      840

ctcctacgac agcagacagg gctttaatgg gaccttcact gtagggccct atatctgtga      900

ggccaccgtc aaaggaaaga agttccagac catcccattt aatgtttatg ctttaaaagc      960

aacatcagag ctggatctag aaatggaagc tcttaaaacc gtgtataagt caggggaaac     1020

gattgtggtc acctgtgctg tttttaacaa tgaggtggtt gaccttcaat ggacttaccc     1080

tggagaagtg aaaggcaaag gcatcacaat gctggaagaa atcaaagtcc catccatcaa     1140

attggtgtac actttgacgg tccccgaggc cacggtgaaa gacagtggag attacgaatg     1200

tgctgcccgc caggctacca gggaggtcaa agaaatgaag aaagtcacta tttctgtcca     1260

tgagaaaggt ttcattgaaa tcaaacccac cttcagccag ttggaagctg tcaacctgca     1320

tgaagtcaaa cattttgttg tagaggtgcg ggcctaccca cctcccagga tatcctggct     1380

gaaaaacaat ctgactctga ttgaaaatct cactgagatc accactgatg tggaaaagat     1440

tcaggaaata aggtatcgaa gcaaattaaa gctgatccgt gctaaggaag aagacagtgg     1500

ccattatact attgtagctc aaaatgaaga tgctgtgaag agctatactt ttgaactgtt     1560

aactcaagtt ccttcatcca ttctggactt ggtcgatgat caccatggct caactggggg     1620

acagacggtg aggtgcacag ctgaaggcac gccgcttcct gatattgagt ggatgatatg     1680

caaagatatt aagaaatgta ataatgaaac ttcctggact attttggcca acaatgtctc     1740

aaacatcatc acggagatcc actcccgaga caggagtacc gtggagggcc gtgtgacttt     1800

cgccaaagtg gaggagacca tcgccgtgcg atgcctggct aagaatctcc ttggagctga     1860

gaaccgagag ctgaagctgg tggctcccac cctgcgttct gaactcacgg tggctgctgc     1920

agtcctggtg ctgttggtga ttgtgatcat ctcacttatt gtcctggttg tcatttggaa     1980

acagaaaccg aggtatgaaa ttcgctggag ggtcattgaa tcaatcagcc cagatggaca     2040

tgaatatatt tatgtggacc cgatgcagct gccttatgac tcaagatggg agtttccaag     2100

agatggacta gtgcttggtc gggtcttggg gtctggagcg tttgggaagg tggttgaagg     2160

aacagcctat ggattaagcc ggtcccaacc tgtcatgaaa gttgcagtga agatgctaaa     2220

acccacggcc agatccagtg aaaaacaagc tctcatgtct gaactgaaga taatgactca     2280

cctggggcca catttgaaca ttgtaaactt gctgggagcc tgcaccaagt caggccccat     2340

ttacatcatc acagagtatt gcttctatgg agatttggtc aactatttgc ataagaatag     2400

ggatagcttc ctgagccacc acccagagaa gccaaagaaa gagctggata tctttggatt     2460

gaaccctgct gatgaaagca cacggagcta tgttatttta tcttttgaaa acaatggtga     2520

ctacatggac atgaagcagg ctgatactac acagtatgtc cccatgctag aaaggaaaga     2580

ggtttctaaa tattccgaca tccagagatc actctatgat cgtccagcct catataagaa     2640

gaaatctatg ttagactcag aagtcaaaaa cctcctttca gatgataact cagaaggcct     2700

tactttattg gatttgttga gcttcaccta tcaagttgcc cgaggaatgg agtttttggc     2760

ttcaaaaaat tgtgtccacc gtgatctggc tgctcgcaac gtcctcctgg cacaaggaaa     2820

aattgtgaag atctgtgact ttggcctggc cagagacatc atgcatgatt cgaactatgt     2880

gtcgaaaggc agtacctttc tgcccgtgaa gtggatggct cctgagagca tctttgacaa     2940

cctctacacc acactgagtg atgtctggtc ttatggcatt ctgctctggg agatcttttc     3000

ccttggtggc accccttacc ccggcatgat ggtggattct actttctaca ataagatcaa     3060

gagtgggtac cggatggcca agcctgacca cgctaccagt gaagtctacg agatcatggt     3120

gaaatgctgg aacagtgagc cggagaagag accctccttt taccacctga gtgagattgt     3180

ggagaatctg ctgcctggac aatataaaaa gagttatgaa aaaattcacc tggacttcct     3240

gaagagtgac catcctgctg tggcacgcat gcgtgtggac tcagacaatg catacattgg     3300

tgtcacctac aaaaacgagg aagacaagct gaaggactgg gagggtggtc tggatgagca     3360

gagactgagc gctgacagtg gctacatcat tcctctgcct gacattgacc ctgtccctga     3420

ggaggaggac ctgggcaaga ggaacagaca cagctcgcag acctctgaag agagtgccat     3480

tgagacgggt tccagcagtt ccaccttcat caagagagag gacgagacca ttgaagacat     3540

cgacatgatg gatgacatcg gcatagactc ttcagacctg gtggaagaca gcttcctgta     3600

actggcggat tcgaggggtt ccttccactt ctggggccac ctctggatcc cgttcagaaa     3660

accactttat tgcaatgcag aggttgagag gaggacttgg ttgatgttta aagagaagtt     3720

cccagccaag ggcctcgggg agcgttctaa atatgaatga atgggatatt ttgaaatgaa     3780

ctttgtcagt gttgcctctt gcaatgcctc agtagcatct cagtggtgtg tgaagtttgg     3840

agatagatgg ataagggaat aataggccac agaaggtgaa ctttgtgctt caaggacatt     3900

ggtgagagtc caacagacac aatttatact gcgacagaac ttcagcattg taattatgta     3960

aataactcta accaaggctg tgtttagatt gtattaacta tcttctttgg acttctgaag     4020

agaccactca atccatccat gtacttccct cttgaaacct gatgtcagct gctgttgaac     4080

tttttaaaga agtgcatgaa aaaccatttt tgaaccttaa aaggtactgg tactatagca     4140

ttttgctatc ttttttagtg ttaaagagat aaagaataat aattaaccaa ccttgtttaa     4200

tagatttggg tcatttagaa gcctgacaac tcattttcat attgtaatct atgtttataa     4260

tactactact gttatcagta atgctaaatg tgtaataatg taacatgatt tccctccaga     4320

gaaagcacaa tttaaaacaa tccttactaa gtaggtgatg agtttgacag tttttgacat     4380

ttatattaaa taacatgttt ctctataaag tatggtaata gctttagtga attaaattta     4440

gttgagcata gagaacaaag taaaagtagt gttgtccagg aagtcagaat ttttaactgt     4500

actgaatagg ttccccaatc catcgtatta aaaaacaatt aactgccctc tgaaataatg     4560

ggattagaaa caaacaaaac tcttaagtcc taaaagttct caatgtagag gcataaacct     4620

gtgctgaaca taacttctca tgtatattac ccaatggaaa atataatgat cagcaaaaag     4680

actggatttg cagaagtttt tttttttttt ttcttcatgc ctgatgaaag ctttggcgac     4740

cccaatatat gtattttttg aatctatgaa cctgaaaagg gtcagaagga tgcccagaca     4800

tcagcctcct tctttcaccc cttaccccaa agagaaagag tttgaaactc gagaccataa     4860

agatattctt tagtggaggc tggatgtgca ttagcctgga tcctcagttc tcaaatgtgt     4920

gtggcagcca ggatgactag atcctgggtt tccatccttg agattctgaa gtatgaagtc     4980

tgagggaaac cagagtctgt atttttctaa actccctggc tgttctgatc ggccagtttt     5040

cggaaacact gacttaggtt tcaggaagtt gccatgggaa acaaataatt tgaactttgg     5100

aacagggttg gcattcaacc acgcaggaag cctactattt aaatccttgg cttcaggtta     5160

gtgacattta atgccatcta gctagcaatt gcgaccttaa tttaactttc cagtcttagc     5220

tgaggctgag aaagctaaag tttggttttg acaggttttc caaaagtaaa gatgctactt     5280

cccactgtat gggggagatt gaactttccc cgtctcccgt cttctgcctc ccactccata     5340

ccccgccaag gaaaggcatg tacaaaaatt atgcaattca gtgttccaag tctctgtgta     5400

accagctcag tgttttggtg gaaaaaacat tttaagtttt actgataatt tgaggttaga     5460

tgggaggatg aattgtcaca tctatccaca ctgtcaaaca ggttggtgtg ggttcattgg     5520

cattctttgc aatactgctt aattgctgat accatatgaa tgaaacatgg gctgtgatta     5580

ctgcaatcac tgtgctatcg gcagatgatg ctttggaaga tgcagaagca ataataaagt     5640

acttgactac ctactggtgt aatctcaatg caagccccaa ctttcttatc caactttttc     5700

atagtaagtg cgaagactga gccagattgg ccaattaaaa acgaaaacct gactaggttc     5760

tgtagagcca attagacttg aaatacgttt gtgtttctag aatcacagct caagcattct     5820

gtttatcgct cactctccct tgtacagcct tattttgttg gtgctttgca ttttgatatt     5880

gctgtgagcc ttgcatgaca tcatgaggcc ggatgaaact tctcagtcca gcagtttcca     5940

gtcctaacaa atgctcccac ctgaatttgt atatgactgc atttgtgtgt gtgtgtgtgt     6000

tttcagcaaa ttccagattt gtttcctttt ggcctcctgc aaagtctcca gaagaaaatt     6060

tgccaatctt tcctactttc tatttttatg atgacaatca aagccggcct gagaaacact     6120

atttgtgact ttttaaacga ttagtgatgt ccttaaaatg tggtctgcca atctgtacaa     6180

aatggtccta tttttgtgaa gagggacata agataaaatg atgttataca tcaatatgta     6240

tatatgtatt tctatataga cttggagaat actgccaaaa catttatgac aagctgtatc     6300

actgccttcg tttatatttt tttaactgtg ataatcccca caggcacatt aactgttgca     6360

cttttgaatg tccaaaattt atattttaga aataataaaa agaaagatac ttacatgttc     6420

ccaaaacaat ggtgtggtga atgtgtgaga aaaactaact tgatagggtc taccaataca     6480

aaatgtatta cgaatgcccc tgttcatgtt tttgttttaa aacgtgtaaa tgaagatctt     6540

tatatttcaa taaatgatat ataatttaaa gtta                                 6574


<210>  2648
<211>  3625
<212>  DNA
<213>  homo sapiens

<400>  2648
aagtgggcgc acagtggctt ccgggcccgg acgccatttc cagcggttgc tggttctgac       60

gggttgtagt ctgccaggac aatgagttat gactaccatc agaactgggg ccgtgatggg      120

ggtccccgca gctccggtgg gggctatgga ggggggccag cagggggtca tggaggtaac      180

cgaggctccg gaggaggcgg cggcggcgga gggggtggtc gaggcggcag gggccggcat      240

cccgggcacc tgaaaggccg cgaaatcggc atgtggtacg cgaaaaaaca ggggcagaag      300

aacaaggaag cggagaggca agagagagct gtagtacaca tggatgaacg acgagaagaa      360

caaattgtac agttactgaa ttctgttcaa gcgaagaatg ataaagagtc agaagcacag      420

atatcctggt ttgctcctga ggatcatgga tacggtactg aagtttctac taagaacaca      480

ccatgctcag agaacaaact tgacatccag gaaaagaagt tgataaatca agaaaaaaaa      540

atgtttagaa tcaggaacag atcatatatt gaccgagatt ctgagtatct cttgcaagaa      600

aatgaaccag atggaacttt agaccaaaaa ttattggaag atttacaaaa gaaaaaaaat      660

gaccttcggt atattgaaat gcagcatttc agagaaaagc tgccttcgta tggaatgcaa      720

aaggaattgg taaatttaat tgataaccat caggtaacag taataagtgg tgaaactggt      780

tgtggcaaaa ccactcaagt tactcagttc attttggata actacattga aagaggaaaa      840

ggatctgctt gcagaatagt ttgtactcag ccaagaagaa ttagtgccat ttcagttgcg      900

gaaagagtag ctgcagaaag ggcagaatct tgtggcagtg gtaatagtac tggatatcaa      960

attcgtctcc agagtcggtt gccaaggaaa cagggttcta tcttatactg tacaacagga     1020

atcatccttc agtggctcca gtcagacccg tatttgtcca gtgttagtca tatcgtactt     1080

gatgaaatcc atgaaagaaa tctgcagtca gatgttttaa tgactgttgt taaagacctt     1140

ctcaattttc gatctgactt gaaagtaata ttgatgagtg caacattgaa tgcagaaaag     1200

ttttcagaat attttggtaa ctgtccaatg atacatatac ctggttttac ctttccggtt     1260

gtggaatatc ttttggaaga tgtaattgaa aaaataaggt atgttccaga acaaaaagaa     1320

cacagatccc agtttaagag gggtttcatg caagggcatg taaatagaca agaaaaagaa     1380

gaaaaagaag caatatataa agaacgttgg ccagattatg taagggaact gcgaagaagg     1440

tattctgcaa gtactgtaga tgttatagaa atgatggagg atgataaagt tgatctgaat     1500

ttgattgttg ccctcatccg atacattgtt ttggaagaag aggatggtgc gatactggtc     1560

tttctgccag gctgggacaa tatcagcact ttacatgatc tcttgatgtc acaagtaatg     1620

tttaaatcag ataaattttt aattatacct ttacattcac tgatgcctac agttaaccag     1680

acacaggtgt ttaaaagaac ccctcctggt gttcggaaaa tagtaattgc taccaacatt     1740

gcggagacta gcattaccat agatgatgtc gtttatgtga tagatggagg aaaaataaaa     1800

gagacgcatt ttgatactca gaacaatatc agtacaatgt ccgctgagtg ggttagtaaa     1860

gctaatgcca aacagagaaa aggtcgagct ggaagagttc aacctggtca ttgctatcat     1920

ctgtataatg gtcttagagc aagtcttcta gatgactatc aactgccaga aattttgaga     1980

actcctttgg aagaactttg tttacaaata aagattttaa ggctaggtgg aattgcttat     2040

tttctgagta gattaatgga cccaccatca aatgaggcag tgttactctc cataagacac     2100

ctgatggagc tgaacgcttt ggataaacaa gaagaattga cacctcttgg agtccacttg     2160

gcacgattac ccgttgagcc acatattgga aaaatgattc tttttggagc actgttctgc     2220

tgcttagacc cagtactcac tattgctgct agtctcagtt tcaaagatcc atttgtcatt     2280

ccactgggaa aagaaaagat tgcagatgca agaagaaagg aattggcaaa ggatactaga     2340

agtgatcact taacagttgt gaatgcgttt gagggctggg aagaggctag gcgacgtggt     2400

ttcagatacg aaaaggacta ttgctgggaa tattttctgt cttcaaacac actgcagatg     2460

ctgcataaca tgaaaggaca gtttgctgag catcttcttg gagctggatt tgtaagcagt     2520

agaaatccta aagatccaga atctaatata aattcagata atgagaagat aattaaagct     2580

gtcatctgtg ctggtttata tcccaaagtt gctaaaattc gactaaattt gggtaaaaaa     2640

agaaaaatgg taaaagttta cacaaaaacc gatggcctgg ttgctgttca tcctaaatct     2700

gttaatgtgg agcaaacaga ctttcactac aactggctta tctatcacct aaagatgaga     2760

acaagcagta tatacttgta tgactgcaca gaggtttccc catactgtct cttgtttttt     2820

ggaggtgaca tttccatcca gaaggataac gatcaggaaa ctattgctgt agatgagtgg     2880

attgtatttc agtctccagc aagaattgcc catcttgtta aggaattaag aaaggaacta     2940

gatattcttc tgcaagagaa gattgaaagt cctcatcctg tagactggaa tgacactaaa     3000

tccagagact gtgcagtact gtcagctatt atagacttga tcaaaacaca ggaaaaggca     3060

actcccagga actttccgcc acgattccag gatggatatt acagctgaca gcttttcagg     3120

ggtggtctga aaagccagtt tgacagccat tcttcatcat tgtttaaatt ttggctggat     3180

gccaaaccct gggacatgaa caattttcat gtgtaaggta gaagccttca gtaggtagta     3240

aagacttaat gtgcatgact tgatgttata tgtagagata tatatatata tatatatata     3300

ccataaaagc aatatgttct ctgatcatat actctgctgt ggtcatgccc actctttggg     3360

agtatattcc ctttatatat attgagtatt gtaccacttg agaaattcct ttgttctgtt     3420

atacaaaatt aatctttctg ctcataatga ttgatgatac caccagtaaa aataggatgt     3480

ttaccccaaa acaagtgtca attaagaatt tgaacacaac cacatttttt aaaatgaaac     3540

ttctatcgga agtaaattaa tttgttgtaa taaagtccag tatttaataa aatgtacaat     3600

gttaaatctc aaaaaaaaaa aaaaa                                           3625


<210>  2649
<211>  3366
<212>  DNA
<213>  homo sapiens

<400>  2649
cgtgggattt ccagaccgcg gctttctaat cggctcggga ggaagctctg cagctctctt       60

gggaattaag ctcaatctct ggactctctc tctttctctt tctccccctc cctctcctgc      120

gaagaagctc aagacaaaac caggaagccg gcgaccctca cctcctcggg ggctgggagg      180

aaggaggaaa acgaaagtcg ccgccgccgc gctgtccccc gagagctgcc tttcctcggg      240

catccctggg gctgccgcgg gacctcgcag ggcggatata aagaaccgcg gccttgggaa      300

gaggcggaga ccggctttta aagaaagaag tcctgggtcc tgcggtctgg ggcgaggcaa      360

gggcgctttt ctgcccacgc tccccgtggc ccatcgatcc cccgcgcgtc cgccgctgtt      420

ctaaggagag aagtgggggc cccccaggct cgcgcgtgga gcgaagcagc atgggcagtc      480

ggtgcgcgct ggccctggcg gtgctctcgg ccttgctgtg tcaggtctgg agctctgggg      540

tgttcgaact gaagctgcag gagttcgtca acaagaaggg gctgctgggg aaccgcaact      600

gctgccgcgg gggcgcgggg ccaccgccgt gcgcctgccg gaccttcttc cgcgtgtgcc      660

tcaagcacta ccaggccagc gtgtcccccg agccgccctg cacctacggc agcgccgtca      720

cccccgtgct gggcgtcgac tccttcagtc tgcccgacgg cgggggcgcc gactccgcgt      780

tcagcaaccc catccgcttc cccttcggct tcacctggcc gggcaccttc tctctgatta      840

ttgaagctct ccacacagat tctcctgatg acctcgcaac agaaaaccca gaaagactca      900

tcagccgcct ggccacccag aggcacctga cggtgggcga ggagtggtcc caggacctgc      960

acagcagcgg ccgcacggac ctcaagtact cctaccgctt cgtgtgtgac gaacactact     1020

acggagaggg ctgctccgtt ttctgccgtc cccgggacga tgccttcggc cacttcacct     1080

gtggggagcg tggggagaaa gtgtgcaacc ctggctggaa agggccctac tgcacagagc     1140

cgatctgcct gcctggatgt gatgagcagc atggattttg tgacaaacca ggggaatgca     1200

agtgcagagt gggctggcag ggccggtact gtgacgagtg tatccgctat ccaggctgtc     1260

tccatggcac ctgccagcag ccctggcagt gcaactgcca ggaaggctgg gggggccttt     1320

tctgcaacca ggacctgaac tactgcacac accataagcc ctgcaagaat ggagccacct     1380

gcaccaacac gggccagggg agctacactt gctcttgccg gcctgggtac acaggtgcca     1440

cctgcgagct ggggattgac gagtgtgacc ccagcccttg taagaacgga gggagctgca     1500

cggatctcga gaacagctac tcctgtacct gcccacccgg cttctacggc aaaatctgtg     1560

aattgagtgc catgacctgt gcggacggcc cttgctttaa cgggggtcgg tgctcagaca     1620

gccccgatgg agggtacagc tgccgctgcc ccgtgggcta ctccggcttc aactgtgaga     1680

agaaaattga ctactgcagc tcttcaccct gttctaatgg tgccaagtgt gtggacctcg     1740

gtgatgccta cctgtgccgc tgccaggccg gcttctcggg gaggcactgt gacgacaacg     1800

tggacgactg cgcctcctcc ccgtgcgcca acgggggcac ctgccgggat ggcgtgaacg     1860

acttctcctg cacctgcccg cctggctaca cgggcaggaa ctgcagtgcc cccgtcagca     1920

ggtgcgagca cgcaccctgc cacaatgggg ccacctgcca cgagaggggc caccgctatg     1980

tgtgcgagtg tgcccgaggc tacgggggtc ccaactgcca gttcctgctc cccgagctgc     2040

ccccgggccc agcggtggtg gacctcactg agaagctaga gggccagggc gggccattcc     2100

cctgggtggc cgtgtgcgcc ggggtcatcc ttgtcctcat gctgctgctg ggctgtgccg     2160

ctgtggtggt ctgcgtccgg ctgaggctgc agaagcaccg gcccccagcc gacccctgcc     2220

ggggggagac ggagaccatg aacaacctgg ccaactgcca gcgtgagaag gacatctcag     2280

tcagcatcat cggggccacg cagatcaaga acaccaacaa gaaggcggac ttccacgggg     2340

accacagcgc cgacaagaat ggcttcaagg cccgctaccc agcggtggac tataacctcg     2400

tgcaggacct caagggtgac gacaccgccg tcagggacgc gcacagcaag cgtgacacca     2460

agtgccagcc ccagggctcc tcaggggagg agaaggggac cccgaccaca ctcaggggtg     2520

gagaagcatc tgaaagaaaa aggccggact cgggctgttc aacttcaaaa gacaccaagt     2580

accagtcggt gtacgtcata tccgaggaga aggatgagtg cgtcatagca actgaggtgt     2640

aaaatggaag tgagatggca agactcccgt ttctcttaaa ataagtaaaa ttccaaggat     2700

atatgcccca acgaatgctg ctgaagagga gggaggcctc gtggactgct gctgagaaac     2760

cgagttcaga ccgagcaggt tctcctcctg aggtcctcga cgcctgccga cagcctgtcg     2820

cggcccggcc gcctgcggca ctgccttccg tgacgtcgcc gttgcactat ggacagttgc     2880

tcttaagaga atatatattt aaatgggtga actgaattac gcataagaag catgcactgc     2940

ctgagtgtat attttggatt cttatgagcc agtcttttct tgaattagaa acacaaacac     3000

tgcctttatt gtcctttttg atacgaagat gtgctttttc tagatggaaa agatgtgtgt     3060

tattttttgg atttgtaaaa atatttttca tgatatctgt aaagcttgag tattttgtga     3120

tgttcgtttt ttataattta aattttggta aatatgtaca aaggcacttc gggtctatgt     3180

gactatattt ttttgtatat aaatgtattt atggaatatt gtgcaaatgt tatttgagtt     3240

ttttactgtt ttgttaatga agaaattcct ttttaaaata tttttccaaa ataaatttta     3300

tgaatgacaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaa                                                                3366


<210>  2650
<211>  3366
<212>  DNA
<213>  homo sapiens

<400>  2650
cgtgggattt ccagaccgcg gctttctaat cggctcggga ggaagctctg cagctctctt       60

gggaattaag ctcaatctct ggactctctc tctttctctt tctccccctc cctctcctgc      120

gaagaagctc aagacaaaac caggaagccg gcgaccctca cctcctcggg ggctgggagg      180

aaggaggaaa acgaaagtcg ccgccgccgc gctgtccccc gagagctgcc tttcctcggg      240

catccctggg gctgccgcgg gacctcgcag ggcggatata aagaaccgcg gccttgggaa      300

gaggcggaga ccggctttta aagaaagaag tcctgggtcc tgcggtctgg ggcgaggcaa      360

gggcgctttt ctgcccacgc tccccgtggc ccatcgatcc cccgcgcgtc cgccgctgtt      420

ctaaggagag aagtgggggc cccccaggct cgcgcgtgga gcgaagcagc atgggcagtc      480

ggtgcgcgct ggccctggcg gtgctctcgg ccttgctgtg tcaggtctgg agctctgggg      540

tgttcgaact gaagctgcag gagttcgtca acaagaaggg gctgctgggg aaccgcaact      600

gctgccgcgg gggcgcgggg ccaccgccgt gcgcctgccg gaccttcttc cgcgtgtgcc      660

tcaagcacta ccaggccagc gtgtcccccg agccgccctg cacctacggc agcgccgtca      720

cccccgtgct gggcgtcgac tccttcagtc tgcccgacgg cgggggcgcc gactccgcgt      780

tcagcaaccc catccgcttc cccttcggct tcacctggcc gggcaccttc tctctgatta      840

ttgaagctct ccacacagat tctcctgatg acctcgcaac agaaaaccca gaaagactca      900

tcagccgcct ggccacccag aggcacctga cggtgggcga ggagtggtcc caggacctgc      960

acagcagcgg ccgcacggac ctcaagtact cctaccgctt cgtgtgtgac gaacactact     1020

acggagaggg ctgctccgtt ttctgccgtc cccgggacga tgccttcggc cacttcacct     1080

gtggggagcg tggggagaaa gtgtgcaacc ctggctggaa agggccctac tgcacagagc     1140

cgatctgcct gcctggatgt gatgagcagc atggattttg tgacaaacca ggggaatgca     1200

agtgcagagt gggctggcag ggccggtact gtgacgagtg tatccgctat ccaggctgtc     1260

tccatggcac ctgccagcag ccctggcagt gcaactgcca ggaaggctgg gggggccttt     1320

tctgcaacca ggacctgaac tactgcacac accataagcc ctgcaagaat ggagccacct     1380

gcaccaacac gggccagggg agctacactt gctcttgccg gcctgggtac acaggtgcca     1440

cctgcgagct ggggattgac gagtgtgacc ccagcccttg taagaacgga gggagctgca     1500

cggatctcga gaacagctac tcctgtacct gcccacccgg cttctacggc aaaatctgtg     1560

aattgagtgc catgacctgt gcggacggcc cttgctttaa cgggggtcgg tgctcagaca     1620

gccccgatgg agggtacagc tgccgctgcc ccgtgggcta ctccggcttc aactgtgaga     1680

agaaaattga ctactgcagc tcttcaccct gttctaatgg tgccaagtgt gtggacctcg     1740

gtgatgccta cctgtgccgc tgccaggccg gcttctcggg gaggcactgt gacgacaacg     1800

tggacgactg cgcctcctcc ccgtgcgcca acgggggcac ctgccgggat ggcgtgaacg     1860

acttctcctg cacctgcccg cctggctaca cgggcaggaa ctgcagtgcc cccgtcagca     1920

ggtgcgagca cgcaccctgc cacaatgggg ccacctgcca cgagaggggc caccgctatg     1980

tgtgcgagtg tgcccgaggc tacgggggtc ccaactgcca gttcctgctc cccgagctgc     2040

ccccgggccc agcggtggtg gacctcactg agaagctaga gggccagggc gggccattcc     2100

cctgggtggc cgtgtgcgcc ggggtcatcc ttgtcctcat gctgctgctg ggctgtgccg     2160

ctgtggtggt ctgcgtccgg ctgaggctgc agaagcaccg gcccccagcc gacccctgcc     2220

ggggggagac ggagaccatg aacaacctgg ccaactgcca gcgtgagaag gacatctcag     2280

tcagcatcat cggggccacg cagatcaaga acaccaacaa gaaggcggac ttccacgggg     2340

accacagcgc cgacaagaat ggcttcaagg cccgctaccc agcggtggac tataacctcg     2400

tgcaggacct caagggtgac gacaccgccg tcagggacgc gcacagcaag cgtgacacca     2460

agtgccagcc ccagggctcc tcaggggagg agaaggggac cccgaccaca ctcaggggtg     2520

gagaagcatc tgaaagaaaa aggccggact cgggctgttc aacttcaaaa gacaccaagt     2580

accagtcggt gtacgtcata tccgaggaga aggatgagtg cgtcatagca actgaggtgt     2640

aaaatggaag tgagatggca agactcccgt ttctcttaaa ataagtaaaa ttccaaggat     2700

atatgcccca acgaatgctg ctgaagagga gggaggcctc gtggactgct gctgagaaac     2760

cgagttcaga ccgagcaggt tctcctcctg aggtcctcga cgcctgccga cagcctgtcg     2820

cggcccggcc gcctgcggca ctgccttccg tgacgtcgcc gttgcactat ggacagttgc     2880

tcttaagaga atatatattt aaatgggtga actgaattac gcataagaag catgcactgc     2940

ctgagtgtat attttggatt cttatgagcc agtcttttct tgaattagaa acacaaacac     3000

tgcctttatt gtcctttttg atacgaagat gtgctttttc tagatggaaa agatgtgtgt     3060

tattttttgg atttgtaaaa atatttttca tgatatctgt aaagcttgag tattttgtga     3120

tgttcgtttt ttataattta aattttggta aatatgtaca aaggcacttc gggtctatgt     3180

gactatattt ttttgtatat aaatgtattt atggaatatt gtgcaaatgt tatttgagtt     3240

ttttactgtt ttgttaatga agaaattcct ttttaaaata tttttccaaa ataaatttta     3300

tgaatgacaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaa                                                                3366


<210>  2651
<211>  5189
<212>  DNA
<213>  homo sapiens

<400>  2651
ggactgcgaa aggagcaggg ttgcggagct agggctccag cctgcggccg cgcattcttg       60

cgtctggcca gccgcgagct ctaagggtcg gccccgcccg gtccgccccc gcggctccct      120

gccaggctct cgcgggcgcg ctcggggtgg ggcctcgcgg ctggcggaga tgcggccggg      180

gctgcgcggt ggtgatgcga gcctgctggg cggcgcgccg gggcagccgg agccgcgcgc      240

cgcggcgctg taatcggaca ccaagagcgc tcgcccccgg cctccggcca ctttccattc      300

actccgaggt gcttgattga gcgacgcgga gaagagctcc gggtgccgcg gcactgcagc      360

gctgagattc ctttacaaag aaactcagag gaccgggaag aaagaatttc acctttgcga      420

cgtgctagaa aataaggtcg tctgggaaaa ggactggaga cacaagcgca tccaaccccg      480

gtagcaaact gatgactttt ccgtgctgat ttctttcaac ctcggtattt tcccttggat      540

attaacttgc atatctgaag aaatggcatt ccggacaatt tgcgtgttgg ttggagtatt      600

tatttgttct atctgtgtga aaggatcttc ccagccccaa gcaagagttt atttaacatt      660

tgatgaactt cgagaaacca agacctctga atacttcagc ctttcccacc atcctttaga      720

ctacaggatt ttattaatgg atgaagatca ggaccggata tatgtgggaa gcaaagatca      780

cattctttcc ctgaatatta acaatataag tcaagaagct ttgagtgttt tctggccagc      840

atctacaatc aaagttgaag aatgcaaaat ggctggcaaa gatcccacac acggctgtgg      900

gaactttgtc cgtgtaattc agactttcaa tcgcacacat ttgtatgtct gtgggagtgg      960

cgctttcagt cctgtctgta cttacttgaa cagagggagg agatcagagg accaagtttt     1020

catgattgac tccaagtgtg aatctggaaa aggacgctgc tctttcaacc ccaacgtgaa     1080

cacggtgtct gttatgatca atgaggagct tttctctgga atgtatatag atttcatggg     1140

gacagatgct gctatttttc gaagtttaac caagaggaat gcggtcagaa ctgatcaaca     1200

taattccaaa tggctaagtg aacctatgtt tgtagatgca catgtcatcc cagatggtac     1260

tgatccaaat gatgctaagg tgtacttctt cttcaaagaa aaactgactg acaataacag     1320

gagcacgaaa cagattcatt ccatgattgc tcgaatatgt cctaatgaca ctggtggact     1380

gcgtagcctt gtcaacaagt ggaccacttt cttaaaggcg aggctggtgt gctcggtaac     1440

agatgaagac ggcccagaaa cacactttga tgaattagag gatgtgtttc tgctggaaac     1500

tgataacccg aggacaacac tagtgtatgg catttttaca acatcaagct cagttttcaa     1560

aggatcagcc gtgtgtgtgt atcatttatc tgatatacag actgtgttta atgggccttt     1620

tgcccacaaa gaagggccca atcatcagct gatttcctat cagggcagaa ttccatatcc     1680

tcgccctgga acttgtccag gaggagcatt tacacccaat atgcgaacca ccaaggagtt     1740

cccagatgat gttgtcactt ttattcggaa ccatcctctc atgtacaatt ccatctaccc     1800

aatccacaaa aggcctttga ttgttcgtat tggcactgac tacaagtata caaagatagc     1860

tgtggatcga gtgaacgctg ctgatgggag ataccatgtc ctgtttctcg gaacagatcg     1920

gggtactgtg caaaaagtgg ttgttcttcc tactaacaac tctgtcagtg gcgagctcat     1980

tctggaggag ctggaagtct ttaagaatca tgctcctata acaacaatga aaatttcatc     2040

taaaaagcaa cagttgtatg tgagttccaa tgaaggggtt tcccaggtat ctctgcaccg     2100

ctgccacatc tatggtacag cctgtgctga ctgctgcctg gcgcgggacc cttattgcgc     2160

ctgggatggc cattcctgtt ccagattcta cccaactggg aaacggagga gccgaagaca     2220

agatgtgaga catggaaacc cactgactca atgcagagga tttaatctaa aagcatacag     2280

aaatgcagct gaaattgtcc agtatggagt aaaaaataac accacttttc tggagtgtgc     2340

ccccaagtct ccgcaggcat ctatcaagtg gctgttacag aaagacaaag acaggaggaa     2400

agaggttaag ctgaatgaac gaataatagc cacttcacag ggactcctga tccgctctgt     2460

tcagggttct gaccaaggac tttatcactg cattgctaca gaaaatagtt tcaagcagac     2520

catagccaag atcaacttca aagttttaga ttcagaaatg gtggctgttg tgacggacaa     2580

atggtcccca tggacctggg ccagctctgt gagggcttta cccttccacc cgaaggacat     2640

catgggggca ttcagccact cagaaatgca gatgattaac caatattgca aagacactcg     2700

gcagcaacat cagcagggag atgaatcaca gaaaatgaga ggggactatg gcaagttaaa     2760

ggccctcatc aatagtcgga aaagtagaaa caggaggaat cagttgccag agtcataata     2820

ttttcttatg tgggtcttat gcttccatta acaaatgctc tgtcttcaat gatcaaattt     2880

tgagcaaaga aacttgtgct ttaccaaggg gaattactga aaaaggtgat tactcctgaa     2940

gtgagtttta cacgaactga aatgagcatg cattttcttg tatgatagtg actagcacta     3000

gacatgtcat ggtcctcatg gtgcatataa atatatttaa cttaacccag attttattta     3060

tatctttatt caccttttct tcaaaatcga tatggtggct gcaaaactag aattgttgca     3120

tccctcaatt gaatgagggc catatccctg tggtattcct ttcctgcttt ggggctttag     3180

aattctaatt gtcagtgatt ttgtatatga aaacaagttc caaatccaca gcttttacgt     3240

agtaaaagtc ataaatgcat atgacagaat ggctatcaaa agaaatagaa aaggaagaca     3300

gcatttaaag ttgtataaaa acatgagtta ttcataaaga gaaaatgatg agtttttatg     3360

gttccaatga aatatgttgg ggttttttta agattgtaaa aataatcagt tactggtatc     3420

tgtcactgac ctttgtttcc ttattcagga agataaaaat cagtaaccta ccccatgaag     3480

atatttggtg ggagttatat cagtgaagca gtttggttta tattcttatg ttatcacctt     3540

ccaaacaaaa gcacttactt tttttggaag ttatttattt tagactcaaa gaatataatc     3600

tggcactact cagttattac tgtttgttct cttattccct agtctgtgtg gcaaattaaa     3660

caatataaga aggaaaaatt tgaagtatta gacttctaaa taaggtgtga aatcatcaaa     3720

aagaaaaatc aaagtagaaa ctactaattt tttaagagga atttataaca aatatggcta     3780

gttttcaact tcagtactca aattcaatga ttcttccttt tattaaaacc agtctcagat     3840

atcatactga tttttaagtc aacactatat attttatgat cttttcagtg tgatggcaag     3900

gtgcttgtta tgtctagaaa gtaagaaaac aatatgagga gacattctgt ctttcaaaag     3960

gtaatggtac atacgttcac tggtctctaa gtgtaaaagt agtaaatttt gtgatgaata     4020

aaataattat ctcctaattg tatgttagaa taattttatt agaataattt catactgaaa     4080

ttattttctc caaataaaaa ttagatggaa aaatgtgaaa aaaattattc atgctctcat     4140

atatatttta aaaacactac ttttgctttt ttatttacct tttaagacat tttcatgctt     4200

ccaggtaaaa acagatattg taccatgtac ctaatccaaa tatcatataa acattttatt     4260

tatagttaat aatctatgat gaaggtaatt aaagtagatt atggcctttt taagtattgc     4320

agtctaaaac ttcaaaaact aaaatcattg tcaaaattaa tatgattatt aatcagaata     4380

tcagaatatg attcactatt taaactatga taaattatga taatatatga ggaggcctcg     4440

ctatagcaaa aatagttaaa atgctgacat aacaccaaac ttcatttttt aaaaaatctg     4500

ttgttccaaa tgtgtataat tttaaagtaa tttctaaagc agtttattat aatggtttgc     4560

ctgcttaaaa ggtataatta aacttctttt ctcttctaca ttgacacaca gaaatgtgtc     4620

aatgtaaagc caaaaccatc ttctgtgttt atggccaatc tattctcaaa gttaaaagta     4680

aaattgtttc agagtcacag ttccctttat ttcacataag cccaaactga tagacagtaa     4740

cggtgtttag ttttatacta tatttgtgct atttaattct ttctattttc acaattatta     4800

aattgtgtac actttcatta cttttaaaaa tgtagaaatt cttcatgaac ataactctgc     4860

tgaatgtaaa agaaaatttt ttttcaaaaa tgctgttaat gtatactact ggtggttgat     4920

tggttttatt ttatgtagct tgacaattca gtgacttaat atctattcca tttgtattgt     4980

acataaaatt ttctagaaat acactttttt ccaaagtgta agtttgtgaa tagattttag     5040

catgatgaaa ctgtcataat ggtgaatgtt caatctgtgt aagaaaacaa actaaatgta     5100

gttgtcacac taaaatttaa ttggatattg atgaaatcat tggcctggca aaataaaaca     5160

tgttgaattc cccaaaaaaa aaaaaaaaa                                       5189


<210>  2652
<211>  4800
<212>  DNA
<213>  homo sapiens

<400>  2652
gcggggcgcg gcggcaggaa ctttcccggg gacccctgcg ggaaggcctg gccagtaagc       60

gcgcctcttt ggcccgaatc aacatggaaa cctaaggaaa aacgtctgac ctgcggaggt      120

agtttgggtg gctacttggt gttggacttg gctaaataaa taccagaggc agataaaaca      180

agcgaggggc ctaggtcaag agttccaagt ttgttcctcg ataaaaaacg acaaacgcgg      240

tcgggggcgg tgatgcccgc ctgcagtccc aacactttag gaagctgagg cggggggatc      300

gcaggagttc gagaccagtc tgggcaacat aatgagacca tccccaccac ctcccgtcct      360

taattttttt taataaaaaa aatctttaag tgagaaatgc atctgtaatg tccttattaa      420

ccaaaaacgc ctaagggata aagaagcaca cgctccctag ccaacgctag aggaacacac      480

cccgagagct ggtgctgtag gacccagttt tcccgcgaaa acgctgccgc gcagggggtc      540

agaccatctg gaccaagggg ggccgagcga ggcctacttc tggtttacgc acgggcgctg      600

aaagaagcgg cactgtcccc ccctgccgat gcgcagtggc gcctcccgga ggcggagcca      660

cgtacgagcg ccgctgtgat tggtgaggcc ccgccagggg cggagacgac cttgccgccg      720

gcgggaactc tgggtctcgc ggtttgggag cgctactcgc caggtggact cggagtccgc      780

gagcgtcgtc ggcaagcggc cgcctttcca cggtactccg agcactatgt cgtccccggc      840

gtcgaccccg agccgccgcg gcagccggcg tggaagggcc acccccgccc agacgcctcg      900

gagtgaggat gccaggtcat ctccctctca gagacgtaga ggcgaggatt ccacctccac      960

gggggagttg cagccgatgc caacctcgcc tggagtggac ctgcagagcc ctgctgcgca     1020

ggacgtgctg ttttccagcc ctccccaaat gcattcttca gctatccctc ttgactttga     1080

tgttagttca ccactgacat acggcactcc cagctctcgg gtagagggaa ccccaagaag     1140

tggtgttagg ggcacacctg tgagacagag gcctgacctg ggctctgcac agaagggcct     1200

gcaagtggat ctgcagtctg acggggcagc agcagaagat atagtggcaa gtgagcagtc     1260

tctaggccaa aaacttgtga tctggggaac agatgtaaat gtggcagcat gcaaagaaaa     1320

ctttcagaga tttcttcagc gttttattga ccctctggct aaagaagaag aaaatgttgg     1380

catagatatt actgaacctc tatacatgca acgacttggg gagattaatg ttattggtga     1440

gccattttta aatgtgaact gtgaacacat caaatcattt gacaaaaatt tgtacagaca     1500

actcatctct tacccacagg aagttattcc aacttttgac atggctgtca atgaaatctt     1560

ctttgaccgt taccctgact caatcttaga acatcagatt caagtaagac cattcaacgc     1620

attgaagact aagaatatga gaaacctgaa tccagaagac attgaccagc tcatcaccat     1680

cagcggcatg gtgatcagga catcccagct gattcccgag atgcaggagg ccttcttcca     1740

gtgccaagtg tgtgcccaca cgacccgggt ggagatggac cgcggccgca ttgcagagcc     1800

cagtgtgtgc gggcgctgcc acaccaccca cagcatggca ctcatccaca accgctccct     1860

cttctctgac aagcagatga tcaagcttca ggagtctccg gaagacatgc ctgcagggca     1920

gacaccacac acagttatcc tgtttgctca caatgatctc gttgacaagg tccagcctgg     1980

ggacagagtg aatgttacag gcatctatcg agctgtgcct attcgagtca atccaagagt     2040

gagtaatgtg aagtctgtct acaaaaccca cattgatgtc attcattatc ggaaaacgga     2100

tgcaaaacgt ctgcatggcc ttgatgaaga agcagaacag aaactttttt cagagaaacg     2160

tgtggaattg cttaaggaac tttccaggaa accagacatt tatgagaggc ttgcttcagc     2220

cttggctcca agcatttatg aacatgaaga tataaagaag ggaattttgc ttcagctctt     2280

tggcgggaca aggaaggatt ttagtcacac tggaaggggc aaatttcggg ctgagatcaa     2340

catcttgctg tgtggcgacc ctggtaccag caagtcccag ctgctgcagt acgtgtacaa     2400

cctcgtcccc aggggccagt acacgtctgg gaagggctcc agtgcagttg gcctcactgc     2460

gtacgtaatg aaagaccctg agacaaggca gctggtcctg cagacaggtg ctcttgtcct     2520

gagtgacaac ggcatctgct gtatcgatga gttcgacaag atgaatgaaa gtacaagatc     2580

ggtattgcat gaagtcatgg aacagcagac tctgtccatt gcaaaggctg ggatcatctg     2640

tcagctcaat gcgcgcacct ctgtcctggc agcagcaaat cccattgagt ctcagtggaa     2700

tcctaaaaaa acaaccattg aaaacatcca gctgcctcat actttattat caaggtttga     2760

tttgatcttc ctcttgctgg accctcagga cgaagcctat gacaggcgtc tggctcacca     2820

cctggtcgca ctgtactacc agagcgagga gcaggcagag gaggagctcc tggacatggc     2880

ggtgctaaag gactacattg cctacgcgca cagcaccatc atgccgcggc taagtgagga     2940

agccagccag gctctcatcg aggcttatgt agacatgagg aagattggca gtagccgggg     3000

aatggtttct gcataccctc gacagctaga gtcattaatc cgcttagcag aagcccatgc     3060

taaagtaaga ttgtctaaca aagttgaagc cattgatgtg gaagaggcca aacgcctcca     3120

tcgggaagct ctgaagcagt ctgcaactga tccccggact ggcatcgtgg acatatctat     3180

tcttactacg gggatgagtg ccacctctcg taaacggaaa gaagaattag ctgaagcatt     3240

gaaaaagctt attttatcta agggcaaaac accagctcta aaataccagc aactttttga     3300

agatattcgg ggacaatctg acatagcaat tactaaagat atgtttgaag aagcactgcg     3360

tgccctggca gatgatgatt tcctgacagt gactgggaag accgtgcgct tgctctgaag     3420

ccttgtgagc aaggaaggct ccctgcatgt cctgcttgct gcacgccaca tgggtgtggt     3480

ctgcatctca gttggccgcc atcagtgtaa atagagctta aagtcatggt ttggctgcat     3540

aaaaattttc taacttgggt tcaatatttg tagtgaagta tctgttttca tttttttcac     3600

gttataaata aaaatactat gctggccggg cgcggtggct cacacctgta atcccagcac     3660

tttgggaggc caatgtgggt ggatcatgag gtcaggagtt caagaccagc ctagccaaga     3720

tggtgaaacc ccgtctctag taaagataac aaaaaattag ctgggcttga tggcatgcgc     3780

ctgtaatccc agctactcgg gaggttgagg caggagaatc gcttaaaccc aggcggcaga     3840

ggttgcagtg agccaagatc gcgccactgc actccagcct cagcaataga gtgagactgt     3900

ctcaaaaaaa aaaaaaaaaa aaaaacctgc caattttcaa acataccgta gagattattt     3960

tcaggtgcca ttttatagta tagcagcagg gcttttactc tgtgtatgca cagatgcagt     4020

ctggggcatg gtttgtgtgc tggactttct catggccatc atcagtatgc ttatggattt     4080

gatgacaggc atagcctggg catatcacct cattggtaaa gggctagagc ctttcttttt     4140

tatggcactt ctttttttga gatagggtct tactctgtca ccctggctag agtacactgg     4200

tacaatcacg gctcaatgta ggcttaacct cctgggctca ggtgtatgtc actatgcccg     4260

gctacttttt gtattttttg gtagagacgg cttcgccacg ttgcccaggc tgcaagcgat     4320

atgcctaggc tcaagcgatc tgcccacctc aacttccgga agtgctgaga ttacaggtgt     4380

gagccactgc acccagcctt tgttttattt tttatttttt gagaggtatg attctttcta     4440

gagatttttt ctcatggcta ctattagatc aggaatgggt gattggagat tattagattc     4500

taggttaact tctaccactt taccctaata cataaaactt tttcctaaat aaatgatgga     4560

aggaataata cttggttacc tggcattatt tttcagtaag aaaaaagctt tactaaccac     4620

tacatttatg gaaatttgta ggggtaagta ttttataggt cataaaaaac accataatat     4680

aacgaatctc attttcttta aatgtgaatt aaatcctaac agtcatcttt ataaaatgac     4740

cataggctaa aatcttacgt gtaagtacta ctacaataaa taatttctga aacctttaaa     4800


<210>  2653
<211>  2420
<212>  DNA
<213>  homo sapiens

<400>  2653
ccagccatgc ctcccagcgc gcttcccttc ccccgcctcc tggtcctgca ccctcccctc       60

ccctcccccc gcttcctgcc ttgtgacaca tcccgggccc tcccggaggc ggcagcagca      120

gcagctgcag cggcagcagc ggcagcagag gcagcagcag tagccaccac tccgccgagg      180

ccgcaacccc ggctcggcct ccccaggccc cgccgctgcc gcagtcatgg ctgctgatgg      240

ggtggacgaa cgctcgcctc tgctgtcagc atcccactcc ggaaatgtca ctcccaccgc      300

cccaccgtac ttgcaagaaa gcagccccag agcggagctc ccacctccat atacagccat      360

tgccagtcca gacgccagtg gtattccagt aataaactgc cgtgtgtgcc aatcactaat      420

caatttggat ggcaagcttc accagcatgt ggttaagtgc acagtttgca atgaagctac      480

gccaatcaaa aaccccccaa caggcaagaa atatgttaga tgcccttgta attgtcttct      540

catttgtaag gacacatctc ggcgaatagg atgcccaaga cccaactgta gacggataat      600

taaccttggc ccagtaatgc ttatttctga agaacaacca gctcagcctg cattgccaat      660

ccaaccagaa ggtacaaggg tcgtgtgtgg gcactgtgga aacacattcc tgtggatgga      720

actgaggttc aacactctgg caaaatgccc acactgcaaa aaaatctcct cagtgggtag      780

tgcacttcca cgaagacgct gctgtgcata tattaccatt ggaatgatat gtattttcat      840

tggagttggg ttaactgttg gcaccccaga ttttgcaagg cgatttcgag caacctatgt      900

ttcttgggca attgcttatc tcctaggatt gatctgcctt atccgagctt gttattgggg      960

agccataaga gtcagttatc cagaacacag ttttgcataa gcttgtttat gattcagtaa     1020

tgcaggtgag agtgtctagc agttcttggt aagctactct ggacatcttt aaattattta     1080

tcctaatgga ttccattctg gtttatgtat aatcgtttca agactttggg agtcttttat     1140

gaacaaatgc tcattgcact atattatatg caaattgttt tgctgctagg ttttcaaaat     1200

ttgaataata aagccttttc atgttctttt acatctctta tagatatttt tggatttgtt     1260

accaaacatt acatttactc tcaccctttt attattttta aataagttat ttcattactt     1320

gctgatacat gagtattcct aagtgtttat aaatatttct ataatagttt cacatttata     1380

tttacatttt aattaaacag tatcaaaatt gcttgcttaa aacctaagca atatgcattt     1440

tgcttgaact gcttactgta actttaacct aagattatag tgaccttatt caggaaaaaa     1500

aaaaaaattt agtgtaactt caaagacttg acattcttgt cagaggaaaa aaaatttcta     1560

gatactgttt gcttgttttt tgttgtttgt agaaagataa aatattttgg tagtaattta     1620

aaatacaaga acgaatattt atttgtccac agttggagat gttggataaa tgtcttttct     1680

caaagatcac aggacttttg tctttcattt ttgccttttt atttaccatt tataaaagat     1740

ctggtctgga ttatggaatt taatgtttat cagctctatg tattccttta tagaggcttg     1800

aggaagtatt tcacataaca tgttttataa tacttaacca tttatccaaa gatatattta     1860

cattgggttg tgcccctttc ccttagatca tggtaaattt ttcttattga ggtaattatg     1920

tactacttat atttgaagga agcttatgac attttacagt agctaaaatg ttgagattag     1980

aggtactttt actattcttc tcaaaggtaa ctgatcagat aattacccaa attattcaag     2040

aaaatagatc agaaataaag aacaacataa ttttctaaga attcattgaa atttatggaa     2100

tcagctctcg cactgcccat ctttgcagtt ttgaaaaaga aattgcttaa tcacaaatgt     2160

tctacagtct ttaaatgtag tagaattaga cagtgagatc atctgagtaa attgattggt     2220

gattccagag ataagactaa tattttaaat tatttatgat actgattagt ataaaaacgt     2280

actcatcaca gaatttgaag caaaatacat gtacacttca aagagtaaat gacaaatgta     2340

taaatgctgt agctcaggat tatatgtacc tttaaaaata cactaataaa gattattgtt     2400

caaaaaaaaa aaaaaaaaaa                                                 2420


<210>  2654
<211>  8406
<212>  DNA
<213>  homo sapiens

<400>  2654
gccatttcca gagaggaaca accgtgtaga ctgctttcct gggagtcaag ttaaaacttc       60

tctcctgtga ccttgtcacc cggcagtgga aagttaccct tggctgcagc cacgacttcc      120

gcatactctt cagaacttgc tctgcccttg agttttccag ctttccttta atgcactaaa      180

cctttaatat tgtattctcc taaatgagac gtctcgcatt tgagcaggta acactcggga      240

gagtcccgta ttctcagagt aaaagttgtt tctggaattg atctcgccaa aaaggacatc      300

tttggagcca gcttctgctc cattgctgtt gaactttttt ttggtcgtga catcagaaaa      360

ataaccaagt gtgagtctga taatagcaat gatccgtatg tgaaactttc attgtacgta      420

gcggatgaga atagagaact tgctttggtc cagacaaaaa caattaaaaa gacactgaac      480

ccaaaatgga atgaagaatt ttatttcagg gtaaacccat ctaatcacag actcctattt      540

gaagtatttg acgaaaatag actgacacga gacgacttcc tgggccaggt ggacgtgccc      600

cttagtcacc ttccgacaga agatccaacc atggagcgac cctatacatt taaggacttt      660

ctcctcagac caagaagtca taagtctcga gttaagggat ttttgcgatt gaaaatggcc      720

tatatgccaa aaaatggagg tcaagatgaa gaaaacagtg accagaggga tgacatggag      780

catggatggg aagttgttga ctcaaatgac tcggcttctc agcaccaaga ggaacttcct      840

cctcctcctc tgcctcccgg gtgggaagaa aaagtggaca atttaggccg aacttactat      900

gtcaaccaca acaaccggac cactcagtgg cacagaccaa gcctgatgga cgtgtcctcg      960

gagtcggaca ataacatcag acagatcaac caggaggcag cacaccggcg cttccgctcc     1020

cgcaggcaca tcagcgaaga cttggagccc gagccctcgg agggcgggga tgtccccgag     1080

ccttgggaga ccatttcaga ggaagtgaat atcgctggag actctctcgg tctggctctg     1140

cccccaccac cggcctcccc aggatctcgg accagccctc aggagctgtc agaggaacta     1200

agcagaaggc ttcagatcac tccagactcc aatggggaac agttcagctc tttgattcaa     1260

agagaaccct cctcaaggtt gaggtcatgc agtgtcaccg acgcagttgc agaacagggc     1320

catctaccac cgccatcagt ggcctatgta cataccacgc cgggtctgcc ttcaggctgg     1380

gaagaaagaa aagatgctaa ggggcgcaca tactatgtca atcataacaa tcgaaccaca     1440

acttggactc gacctatcat gcagcttgca gaagatggtg cgtccggatc agccacaaac     1500

agtaacaacc atctaatcga gcctcagatc cgccggcctc gtagcctcag ctcgccaaca     1560

gtaactttat ctgccccgct ggagggtgcc aaggactcac ccgtacgtcg ggctgtgaaa     1620

gacacccttt ccaacccaca gtccccacag ccatcacctt acaactcccc caaaccacaa     1680

cacaaagtca cacagagctt cttgccaccc ggctgggaaa tgaggatagc gccaaacggc     1740

cggcccttct tcattgatca taacacaaag actacaacct gggaagatcc acgtttgaaa     1800

tttccagtac atatgcggtc aaagacatct ttaaacccca atgaccttgg cccccttcct     1860

cctggctggg aagaaagaat tcacttggat ggccgaacgt tttatattga tcataatagc     1920

aaaattactc agtgggaaga cccaagactg cagaacccag ctattactgg tccggctgtc     1980

ccttactcca gagaatttaa gcagaaatat gactacttca ggaagaaatt aaagaaacct     2040

gctgatatcc ccaataggtt tgaaatgaaa cttcacagaa ataacatatt tgaagagtcc     2100

tatcggagaa ttatgtccgt gaaaagacca gatgtcctaa aagctagact gtggattgag     2160

tttgaatcag agaaaggtct tgactatggg ggtgtggcca gagaatggtt cttcttactg     2220

tccaaagaga tgttcaaccc ctactacggc ctctttgagt actctgccac ggacaactac     2280

acccttcaga tcaaccctaa ttcaggcctc tgtaatgagg atcatttgtc ctacttcact     2340

tttattggaa gagttgctgg tctggccgta tttcatggga agctcttaga tggtttcttc     2400

attagaccat tttacaagat gatgttggga aagcagataa ccctgaatga catggaatct     2460

gtggatagtg aatattacaa ctctttgaaa tggatcctgg agaatgaccc tactgagctg     2520

gacctcatgt tctgcataga cgaagaaaac tttggacaga catatcaagt ggatttgaag     2580

cccaatgggt cagaaataat ggtcacaaat gaaaacaaaa gggaatatat cgacttagtc     2640

atccagtgga gatttgtgaa cagggtccag aagcagatga acgccttctt ggagggattc     2700

acagaactac ttcctattga tttgattaaa atttttgatg aaaatgagct ggagttgctc     2760

atgtgcggcc tcggtgatgt ggatgtgaat gactggagac agcattctat ttacaagaac     2820

ggctactgcc caaaccaccc cgtcattcag tggttctgga aggctgtgct actcatggac     2880

gccgaaaagc gtatccggtt actgcagttt gtcacaggga catcgcgagt acctatgaat     2940

ggatttgccg aactttatgg ttccaatggt cctcagctgt ttacaataga gcaatggggc     3000

agtcctgaga aactgcccag agctcacaca tgctttaatc gccttgactt acctccatat     3060

gaaacctttg aagatttacg agagaaactt ctcatggccg tggaaaatgc tcaaggattt     3120

gaaggggtgg attaagcacc ctgtgcctcg ggggtggttg ttcttcaagc aagttctgct     3180

tgcacttttg catttgccta acagactttt gcagaggcga tggcagagag cagctgcagg     3240

catggtccct ggagccgagc cttcaccacg cactcgtcca agttcggatg cgggaacctg     3300

gtcccagctt gagttcctgc ctttcccacc acaaattatc aactggttga tgtgtacact     3360

aattacattt caggaggact taatgctatt tatgttgtgc ctctgcaggc aaagccctta     3420

ataaatattt tacatccttt ctaatgacaa tgaatggaat taatcactca acaggtatag     3480

tattacgact catgtttact ttttaaaatg atttagaccg attttcagat tttatttcgt     3540

tatgattaaa gatgtctcat gtacttggaa aagtgagcat tttttttttt tttgtatttc     3600

actttcatac caggcttaat gtcaatgaca tttttatttt tgaagtactc tgacacctcc     3660

accctctact ttattagaat tggaaggcaa atttttgtcc aaaaacctac agacaagtac     3720

tttgagagaa tttccaatat aatattagac ataatgataa ttttttccat actcagaatg     3780

aaaaactgga tattacgttt ttgttttggg gtttttttgt acaaatttag ctaatagcta     3840

caggctgaga gaattgtaac atagcatgac aaattttgtg ttgacttgaa aggaatcaca     3900

ccattattcc ttagaagtaa ttacatgtgt tctaacacat ttgagacagg gttggactcc     3960

catttctcat ccgagaaatt acttaaccct tcctggcgct gtacagtcat cttttattct     4020

atttcctctt tgctgtttgt agtagagaca ttttgaatga aacttggcac tgcttgattc     4080

aaaactgtgg aaaccagatc tgtttagtct cctgtttgta tgcgtttgct aatggtagct     4140

aaataaccag tttttgttgt aaatgcacca attctgaagg cactttatgt actacatgga     4200

ggtcatatct ggttttgttt ttattttttt atcatgaaca ttaaatgtga tgatgatttc     4260

ttttccctgc acacatcttt ccggtgcaat atctatcaat tgtgaatctg gctgctggtg     4320

tataaaaacc tggatgtaaa gctgagccta cagacctgtc ctcaccaact gttttgtgat     4380

ttctactcaa ctacaaagat ttatttaatg tactcttaat ctaactgagt tttgttacca     4440

atgacctgtt gcatgcttca ataccgtgta ctgcctgagt tgtgcctctt gtgtgctaga     4500

ttaaaagtga gacagagact tgacttgatc ctctgagctc aagctattga gctggtagtg     4560

gcagaggact gagggtacct gcacagtttg attcttttcc acgtgtaagt ctccattgca     4620

gaattgtcgt gctttgagaa aacacctgag gcagtgtggg agttgaacga ccctgctgtc     4680

ctttttaacc tgtgttgtcc tagaccctgt cggggcagtc aggggacact agagatttga     4740

tctcatgcga gtcatcaata ggacaaaaaa gttgtggttt ggggaggtct gtttgttaca     4800

taaaaaggac ctttcggtgt aagaaattgc cgtttttacc ctgccctggc tggcatgtga     4860

gaagccatgg aaggttgtgg ttgtaaatga gttgtctaaa ggggtgcaga ggcctgaggt     4920

ttctaaaaga aggtagattt ctacagagct gagtgttggt tcctttttct tattggttga     4980

aaattacctg gtagtgatca gaaaacttag atgctatgta actaaaaaaa aaaaaaaaaa     5040

aaaaaaaaaa aaaaaaaaaa ttcccgctca tgagttttga ctattggtga gatgttttcc     5100

gctacagtta acatgacaaa tgtctcagtg gcaaaaatcc cctttttgta agcccccata     5160

gtctagaggc agttttcttt ttaagaatca tgccagagcc tgagtcgagc agtatgcttt     5220

cttggttttt gagagtaatt gtgtaattgt agagggagaa atccaattct aacctaagaa     5280

ctgggattct tctgtcatct tgtaaaccgt atattgaaaa aaacagaatg tcactaaatg     5340

catattaagt caagtattgg aaagtataaa agaaaaatca ttctgacaat ttctaagcca     5400

gaagcaaaca agaattactg aaatctaccc catgaatact tggaaggcag taattgtgag     5460

tgacacctca gttcatcaac cccttaataa tatcagctta attttaatga caactaaata     5520

tgctgaagtg aggatttagt attttttaaa aaagcaaaac aaggttcagt agtcctcagc     5580

aattctccaa gtttctctct ttgcctaaaa tggtcataga tcttgatttc tctgaatcgt     5640

gatgaccaca cccagtcatc ttcacagcat aattgcaggt ggcagtaaag agagtgtgct     5700

gggtaaggag cagttgctgg gtcattcctt gggccccgac ctgcccgggg agtagccctg     5760

ggggagagag ggcagtgttg cctatcccag aggtcccagc agtcacactg ctctgcaggc     5820

cgggctctct ttatagccag agaaatcacc ttaatgcagt ctctttagtt gtctgctgaa     5880

gctgtagtta ttatgggcca cttacatgag gctgagaagt acgtgccgga gctcacacac     5940

tgcctgttgc ggttctctta acatcagtta tcacagctgc ctgtgggtcc cgggtatttc     6000

cattcctgcc ccttgttggc ccgaggaagg atgtggaaag agcacctggt gggatgaagg     6060

tccaacagcc tgtgcctctc cactgctggc cctggagccg gcagcagtga ggcattcatt     6120

gtctgtgttg cggtgtattc ccagcttcag tgctcttttc ctttttgcct gaaatgttta     6180

tgcttctctg cagccagtcc tctaacaaat ctcaagaaca aaggtaagac acttggtttt     6240

tgtttccagg acccttcaga aggtgacatc agatattccc taaattcaga caatgaggga     6300

tacagagcga cttggcatgt attatttctc ccatgtaagg acaaagggac agattattat     6360

tgttatttct gagacagagt cttgctctgt agctcaggct ggagtgcagt ggctcaatct     6420

cagctcacca caacctctgc ctcctggctt caagcgattc ttctgcctca gcctccccga     6480

atagttggga ttacaggcac ccaccaccac gcctggctaa tttttgtatt tttagtagag     6540

atggtttcac catgctggcc aggctggtct tgaactcctg acctcaggtg atcctcccgc     6600

ctcagccttc caaagtgctg ggattacaag catgagccac cgcacccggc ctcacagtga     6660

cagattctga gaaacagcat gcaaaacatt tgaaccattt tctacatctc ccattgttgc     6720

atagagagtg tgcaccgctg ctatcttgcc agatccacac tggtcctccc gaaagccagg     6780

ttcatacaca gcaacttttt aattattcta acagttaccc attaacagtc gactcctgta     6840

tttctgagag tcttgtactc acctctgaaa tttaaaaacg tataaagaga gcctgggtta     6900

atcagttctg cagcccctac gtgacactgt gctagttctc cttcttctgt ctcctcctta     6960

ccctggccct gcacccctgt acttaagagg gagaggtggg aggtgctgtc tggtatcatt     7020

tgctgcctcg ccagtagagg gtgccgctgt gcagggtaac tgcccgcctg ctcccttcct     7080

gacctcccct gaccccgaag atcactacct ctgtcattca ggcattgggg tacatcctga     7140

taagtcgtgt cagaactgcc aatttcagga ctgagatgtg tttttaaaaa acaaatcctt     7200

ataaactcca ctttgtactt tagattttaa aactggggaa aaatgtgata ttctttggac     7260

cactttttta atttatataa gccttaatga acagtgtcta tacatttgca tacacacacc     7320

cccaccccag agtgttctca gtatgtcaga gaaagtgcca cagcattagg acgggagctt     7380

ggagaacgtt ttctagaaaa gggttagctt cctgttggca tgaaattttc caagcaaacc     7440

tcattaaaca tctgttgttt gttaaagatg ttccactgaa agcaacgcat gtttcaaagg     7500

cacgtctttc cgttcgttgg ttttctgtgt gtaaggagta gcattgctgt tggcgcctaa     7560

cctcgcgtgc actgcattct caaccccgta ccagtgcatc atcagaagcc ttcctcgtga     7620

ccataactct gtgtctgcag atatgtgttc ccgtgtaagc cagttttccc cttttactca     7680

gactgatttc acctagattg tcacggtttc cttcatgtta actttgcgtg actttgttct     7740

tcctttacta ctctgtatgt aatatatata catatatacg tacatatgct gtccaaatat     7800

atttgtatat atttgtatag catttttaca cctttattga gtaatctggt ttcgaaagga     7860

ggtgagagtt tagtcccttc tgcagttttc tccaagctgt gtcctgtgaa tttcaaccct     7920

tggagcctaa gaaaacccta ggaagatgat gttaatttgc tgtcatttcc taattcagga     7980

tctatcatca aatgaaacat gaaaaaaaca gtgactttta aggtgaaaag agtttcaagc     8040

attccaaata aattatcaat gtttcataac tttttattat aaacccacct cctaatagga     8100

agccaagtac tatttgatac agtggtaaaa accaaactac cttgaatttt tttaaggcaa     8160

cttatgaata atgctcattt tcacagtcag aatagcttta aaatatggtt gaatttgata     8220

cacacaggaa gttttcttga agaacaatcc tttcgctttt cttttttctt gagagatcta     8280

aagagaaact gtagattgtt ttcctgacag caaaagacta atgtgacaaa atgaagtcat     8340

tgtaaagaag cgatgcaact tgtcaaatat ttaataaaga attatggaag ctggaacatt     8400

ttctac                                                                8406


<210>  2655
<211>  1878
<212>  DNA
<213>  homo sapiens

<400>  2655
gtacggcctg tccggcgctc gacgttccac ccccctctct ctgctctcag gttggttcag       60

cccccgtcta cactggggtg gtgcttagcc ggcgccagac cgaccctcga cttcggagag      120

gcagcgcggt tcctctgggt gcttccgcct ccccttctcc tgcttctcca gcctcttcgg      180

cctcctcgcc cgccgcggga acccgagacc ccagtgtatg ccccacccct gaccccgctc      240

gcgacatgtc caccccggct cggcggcgcc tcatgcggga cttcaagagg ttgcaggagg      300

atcctccagc cggagtcagc ggggctccgt ccgagaacaa cataatggtg tggaacgcgg      360

tcattttcgg gcctgaaggg accccgtttg aggatggaac atttaaactt acaatagaat      420

tcactgaaga atatccaaat aaaccaccta cagttagatt tgtctctaag atgttccatc      480

caaatgtcta tgcagatggt agtatatgtc tggacatact tcagaaccgt tggagtccaa      540

cctatgatgt gtcttccatt ctaacatcca tacagtctct gttggatgaa cccaatccca      600

atagtccagc aaacagccag gctgctcagc tgtaccagga gaacaaacgg gaatatgaaa      660

agcgtgtttc tgcaatagta gaacaaagct ggcgtgattg ttgaccccgg gtacagttta      720

aagaagctgg ccataagaaa aatatatatt gatgtgtttg tcacctccct actcctgtca      780

ttacatttac tttattaaaa gcaaaataac tgttgtgctg tttccatctt ccttgccaag      840

ttttcctacc ccttctaccc tctccttaaa catcagaaaa caccctctat gaaatcaaat      900

gtactgtacc tgggttactt gcaaaaatta ctaatgcttc agtttttctg ttgtatttca      960

tttccagttt tcaggcagtt atttttatta ttgtacttta agcttttaag atgaattgtt     1020

atacaagagg tgcttatgct tagcttgatg accaggatgt tatttttaac aaaatgattg     1080

ctgaagtgtt tcatcctggc tggtccttca cttgtgttgg atttagaagt gaatgtgttt     1140

ggaatatggc ctacagagaa tagaaacaaa tccatgtaaa caattttgaa ggaggcatgg     1200

gagctaaaaa tcctgtgata ctaagatctc agtcatatga attacaacgt agtatttact     1260

ggcaagaagg agaaagttga aggactcagc taaaggagta cagcaattgt agtaactgac     1320

acatcctctc tttgcaagct gctgactggg cacactcatg ccaagtttca gaattattgg     1380

tcttctgggt ttttgctttt taaaagaggt gtgggagcag aggaatggaa acaatcgtga     1440

gtttttgagc tagggaaagt tggagctcct ttaatctttt taaaggatca gtgctgccct     1500

aagtgaataa actcaattgt ccatctttat tttagagttt taatgaattc aaggaaggga     1560

gcatagcata tctgtggcaa actattttcc actcaaatcc tgagttattg ctgcatgctt     1620

taatttcttc cctttcagca tctgagaacc ttaaagccaa tgtctgcgat ctttttttgg     1680

atatttatac ttttagatat atagtacctt taagtagcag tatgggacaa ggcttgtaaa     1740

tgttttgtct aatgttctat tgtcaccttt tatgcattta tcacttccaa atctaacttt     1800

gcacaagtaa cccatgtaaa aaaaaatgta catttttcaa aagttgtaaa taaaaataac     1860

cttaaaattt catagtca                                                   1878


<210>  2656
<211>  3739
<212>  DNA
<213>  homo sapiens

<400>  2656
accggccccg gcaactgcag tccaggctcc gcctccctac gcccattggc ttattcaatt       60

cacgcaggaa ccaatgggcg gagacggcag ccgcgccgtc tgacggctta gccgcggtgc      120

agactgcggc ggcggtggtc tgaggaagtt ctatcttggc gctaaagcgg agacgcatcc      180

cccgacccga ggctacgatg agcacaccgg ccgtgcccca ggacctgcag ctgcccccga      240

gtcagagggc gcagtccgca ttcaaagagc aaagaagaca aaaactcaag gaacatctgt      300

tgagaagaaa aacgcttttt gcatacaagc aggaaaatga gatgttatcc agtagtagag      360

atcagagagt tgtgacatct gaggaccaag ttcaagaagg gactaaagtg ctgaaactta      420

aaacaaaaat ggctgataaa gaaaacatga agagacctgc agagagcaaa aataatacag      480

tggtggggaa acattgtatt cctttaaaac cttcaaatga actaaccaat tcaactgtag      540

taattgacac acataaacct aaggatagta atcaaactcc gcatttgtta ctaactgaag      600

atgatcccca aagtcaacat atgacattaa gccaggcatt tcaccttaaa aacaatagta      660

aaaagaaaca aatgactaca gaaaaacaaa agcaagatgc taacatgccc aagaaacctg      720

tgcttggatc ttatcgtggc cagattgttc agtctaagat taattcattt agaaaacctc      780

tacaagtcaa agatgagagt tctgcagcaa caaagaaact ttcagccact atacctaaag      840

ccacaaaacc tcagcctgta aacaccagca gtgtaacagt gaaaagtaat agatcctcca      900

atatgactgc cactactaaa tttgtgagca ctacatctca gaacacacaa cttgtgcgac      960

ctcctattag aagtcatcac agtaataccc gggacactgt gaaacaaggc atcagtagaa     1020

cttctgccaa tgttacaatc cggaaagggc ctcatgaaaa agaactatta caatcaaaaa     1080

cagctttatc tagtgtcaaa accagttctt ctcaaggtat aataagaaat aagactctat     1140

caagatccat agcatctgaa gttatagcca ggcctgcttc attgtctaat gataaactga     1200

tggaaaagtc agagcccgtt gaccagcgaa gacatactgc aggaaaagca attgttgata     1260

gtagatcagc tcagcccaaa gaaacctcgg aagagagaaa agctcgtctg agtgagtgga     1320

aagctggcaa aggaagagtg ctaaaaaggc cccctaattc agtagttact cagcatgagc     1380

ctgcaggaca aaatgaaaaa ccagttgggt ctttttggac taccatggca gaagaagatg     1440

aacaaagatt atttactgaa aaagtaaaca acacattttc tgaatgcctg aacttgatta     1500

atgagggatg tccaaaagaa gatatactgg tcacactgaa tgacctgatt aaaaatattc     1560

cagatgccaa aaagcttgtt aagtattgga tatgtcttgc acttattgaa ccaatcacaa     1620

gtcctattga aaatattatt gcaatctatg agaaagccat tctggcaggg gctcagccta     1680

ttgaagagat gcgacacacg attgtagata ttctaacaat gaagagtcaa gaaaaagcta     1740

atttaggaga aaatatggag aagtcttgtg caagcaagga agaagtcaaa gaagtcagta     1800

ttgaagatac aggtgttgat gtagatccag aaaaactgga aatggagagt aaacttcata     1860

gaaatttgct atttcaagat tgtgaaaaag agcaagacaa caaaacaaaa gatccaaccc     1920

atgatgttaa aacccccaat acagaaacga ggacaagttg cttaattaaa tataatgtgt     1980

ctactacgcc atacttgcaa agtgtgaaaa aaaaggtgca gtttgatgga acaaattccg     2040

catttaaaga gctgaagttt ttaacaccag tgagacgttc tcgacgtctt caagagaaaa     2100

cttctaaatt gccagatatg ttaaaagatc attatccttg tgtgtcttca ttggaacagc     2160

taacggagtt gggaagagaa actgatgctt ttgtatgccg ccctaatgca gcactgtgcc     2220

gggtgtacta tgaggctgat acaacataag agaaataaag ctctgttagg gaatggggtt     2280

tttattattt gtggggtgtt ttgttttgag tagctttata ttgctcttag gtctggagtt     2340

ggccatgtac ctatgtatcc taagcattca cggcagtgag ctcctttact aacattcatg     2400

ttatggcaag agttgtcctc tacattggaa agctaatcct accttgtcag tttcaaccaa     2460

ctgagttttt tctttaagaa aggtaaattt tgtcagctag tttactatgt tccttgaata     2520

taaacaggtt ataatactac cctgttcact ttactaaata taagtacagt aatgatgcat     2580

aattagaaaa tgaggtattc taggtaaaat gtatgtttgc cttgacatgt ttttaaaagt     2640

tatgatgtac ctccctgcct ttaaacagaa tacttttttc ttttttttgg cctttctcag     2700

attagtcaaa aattctatag aatgactcac ttcgaatact aagacacagg aggtttagcc     2760

tgctttctta ccaaattcat gttacccaga cttgtgttct cttgcgtccc ttggactgcc     2820

tgttgattga tggaaagtgt ctgcactgac acttttcgtc agtagtctgt agtttcgtgg     2880

cctcttttga ttataactgg ggtcaccaag aaggtttact taattaaata ccgcatttct     2940

aagagaagat actttgtgta agaaaagatg ccacatttag tggtttaact tttgtaactt     3000

cacttgatag tttttaagca attagaatgg agttagggaa agaacatatc atactgaaca     3060

aatgtcattc tagtttagat agcatttcta agataactga tactaatact tgttttcttc     3120

cctataacat aaaaaacttc actgttaagt catgtccctt gaaacatgat agttacatac     3180

acagttttct ctccacacat aaataacacc actaaagttg ttttgtaagg ttccaaacta     3240

atatggcata tatcaactct acagtttcaa ataaatgact ttttaattgt aaaagattag     3300

ttgaaaaact gtatgaatgt gaagatcaca tgcttagtca tttttatgtt cattccactt     3360

tgtatatctt ttctatttat tgacttctca tgttctagag agtaggactt ttattccgtg     3420

tacctgatat atatacaatt aaaatatctg tgtaattatg ttttaatgaa gtttatttca     3480

acagatattt tatgaaatgc agtttaacca cagtgaatga attttagctt tgcttttgaa     3540

atacattgta agatttgact tgaggttttt gacacttaag tacatgctta atgatatatt     3600

ttcaaaagtc atcagtctac ttacataaac tttacctaat ttttttcact ttaacaaaaa     3660

cataactatg cccttgtttt ttcatacttt gacccaaaat atgccatttt gaaataaaat     3720

ttaagctttg atacactct                                                  3739


<210>  2657
<211>  3736
<212>  DNA
<213>  homo sapiens

<400>  2657
accggccccg gcaactgcag tccaggctcc gcctccctac gcccattggc ttattcaatt       60

cacgcaggaa ccaatgggcg gagacggcag ccgcgccgtc tgacggctta gccgcggtgc      120

agactgcggc ggcggtggtc tgaggaagtt ctatcttggc gctaaagcgg agacgcatcc      180

cccgacccga ggctacgatg agcacaccgg ccgtgcccca ggacctgcag ctgcccccga      240

gtcagagggc gcagtccgca ttcaaagagc aaagaagaca aaaactcaag gaacatctgt      300

tgagaagaaa aacgcttttt gcatacaagc aggaaaatga gatgttatcc agtagagatc      360

agagagttgt gacatctgag gaccaagttc aagaagggac taaagtgctg aaacttaaaa      420

caaaaatggc tgataaagaa aacatgaaga gacctgcaga gagcaaaaat aatacagtgg      480

tggggaaaca ttgtattcct ttaaaacctt caaatgaact aaccaattca actgtagtaa      540

ttgacacaca taaacctaag gatagtaatc aaactccgca tttgttacta actgaagatg      600

atccccaaag tcaacatatg acattaagcc aggcatttca ccttaaaaac aatagtaaaa      660

agaaacaaat gactacagaa aaacaaaagc aagatgctaa catgcccaag aaacctgtgc      720

ttggatctta tcgtggccag attgttcagt ctaagattaa ttcatttaga aaacctctac      780

aagtcaaaga tgagagttct gcagcaacaa agaaactttc agccactata cctaaagcca      840

caaaacctca gcctgtaaac accagcagtg taacagtgaa aagtaataga tcctccaata      900

tgactgccac tactaaattt gtgagcacta catctcagaa cacacaactt gtgcgacctc      960

ctattagaag tcatcacagt aatacccggg acactgtgaa acaaggcatc agtagaactt     1020

ctgccaatgt tacaatccgg aaagggcctc atgaaaaaga actattacaa tcaaaaacag     1080

ctttatctag tgtcaaaacc agttcttctc aaggtataat aagaaataag actctatcaa     1140

gatccatagc atctgaagtt atagccaggc ctgcttcatt gtctaatgat aaactgatgg     1200

aaaagtcaga gcccgttgac cagcgaagac atactgcagg aaaagcaatt gttgatagta     1260

gatcagctca gcccaaagaa acctcggaag agagaaaagc tcgtctgagt gagtggaaag     1320

ctggcaaagg aagagtgcta aaaaggcccc ctaattcagt agttactcag catgagcctg     1380

caggacaaaa tgaaaaacca gttgggtctt tttggactac catggcagaa gaagatgaac     1440

aaagattatt tactgaaaaa gtaaacaaca cattttctga atgcctgaac ttgattaatg     1500

agggatgtcc aaaagaagat atactggtca cactgaatga cctgattaaa aatattccag     1560

atgccaaaaa gcttgttaag tattggatat gtcttgcact tattgaacca atcacaagtc     1620

ctattgaaaa tattattgca atctatgaga aagccattct ggcaggggct cagcctattg     1680

aagagatgcg acacacgatt gtagatattc taacaatgaa gagtcaagaa aaagctaatt     1740

taggagaaaa tatggagaag tcttgtgcaa gcaaggaaga agtcaaagaa gtcagtattg     1800

aagatacagg tgttgatgta gatccagaaa aactggaaat ggagagtaaa cttcatagaa     1860

atttgctatt tcaagattgt gaaaaagagc aagacaacaa aacaaaagat ccaacccatg     1920

atgttaaaac ccccaataca gaaacgagga caagttgctt aattaaatat aatgtgtcta     1980

ctacgccata cttgcaaagt gtgaaaaaaa aggtgcagtt tgatggaaca aattccgcat     2040

ttaaagagct gaagttttta acaccagtga gacgttctcg acgtcttcaa gagaaaactt     2100

ctaaattgcc agatatgtta aaagatcatt atccttgtgt gtcttcattg gaacagctaa     2160

cggagttggg aagagaaact gatgcttttg tatgccgccc taatgcagca ctgtgccggg     2220

tgtactatga ggctgataca acataagaga aataaagctc tgttagggaa tggggttttt     2280

attatttgtg gggtgttttg ttttgagtag ctttatattg ctcttaggtc tggagttggc     2340

catgtaccta tgtatcctaa gcattcacgg cagtgagctc ctttactaac attcatgtta     2400

tggcaagagt tgtcctctac attggaaagc taatcctacc ttgtcagttt caaccaactg     2460

agttttttct ttaagaaagg taaattttgt cagctagttt actatgttcc ttgaatataa     2520

acaggttata atactaccct gttcacttta ctaaatataa gtacagtaat gatgcataat     2580

tagaaaatga ggtattctag gtaaaatgta tgtttgcctt gacatgtttt taaaagttat     2640

gatgtacctc cctgccttta aacagaatac ttttttcttt tttttggcct ttctcagatt     2700

agtcaaaaat tctatagaat gactcacttc gaatactaag acacaggagg tttagcctgc     2760

tttcttacca aattcatgtt acccagactt gtgttctctt gcgtcccttg gactgcctgt     2820

tgattgatgg aaagtgtctg cactgacact tttcgtcagt agtctgtagt ttcgtggcct     2880

cttttgatta taactggggt caccaagaag gtttacttaa ttaaataccg catttctaag     2940

agaagatact ttgtgtaaga aaagatgcca catttagtgg tttaactttt gtaacttcac     3000

ttgatagttt ttaagcaatt agaatggagt tagggaaaga acatatcata ctgaacaaat     3060

gtcattctag tttagatagc atttctaaga taactgatac taatacttgt tttcttccct     3120

ataacataaa aaacttcact gttaagtcat gtcccttgaa acatgatagt tacatacaca     3180

gttttctctc cacacataaa taacaccact aaagttgttt tgtaaggttc caaactaata     3240

tggcatatat caactctaca gtttcaaata aatgactttt taattgtaaa agattagttg     3300

aaaaactgta tgaatgtgaa gatcacatgc ttagtcattt ttatgttcat tccactttgt     3360

atatcttttc tatttattga cttctcatgt tctagagagt aggactttta ttccgtgtac     3420

ctgatatata tacaattaaa atatctgtgt aattatgttt taatgaagtt tatttcaaca     3480

gatattttat gaaatgcagt ttaaccacag tgaatgaatt ttagctttgc ttttgaaata     3540

cattgtaaga tttgacttga ggtttttgac acttaagtac atgcttaatg atatattttc     3600

aaaagtcatc agtctactta cataaacttt acctaatttt tttcacttta acaaaaacat     3660

aactatgccc ttgttttttc atactttgac ccaaaatatg ccattttgaa ataaaattta     3720

agctttgata cactct                                                     3736


<210>  2658
<211>  3505
<212>  DNA
<213>  homo sapiens

<400>  2658
gacgcagggt cggcggctca gcgccgtaga gacaaagccg cccgcccgcc agcccgctag       60

ctcctcgcgc gagctcctcc tccacgggaa cctccctccc ctcccaggcg ccgccgcagc      120

cggagcggct cccgggccct gggccgccgc cggccagact gcctgcaagg gatggtcata      180

ctcctggctg cacttccaga gtcttgaaga agaaagcaga tgtggatacc taaatatagg      240

gaagaaatac ttgtgttggc tgcatttcca gggatgctac cagagctcaa ggctgtcacc      300

tggtcttgcc cagaagagcc gttcttagag gcaggacttg atgaaggctt tcctgctgat      360

ggaataggtt tgctagagct ggccttggaa ttagaaccct tcatgtggcc tttataaata      420

tgcgtttgag acagagttat atgcagaagt tgaaaatgcc tggaagattt ctggtttctt      480

tcactactta tcctgccttt ttgcatcgct gccagatttg gatgatatga tattcagagg      540

ggcaccttaa tcaaagccat tcttcaacaa gacccacctg gcataagatt gcacacataa      600

ttcaagatgg ccagtcaacc tcctgaagac actgcggagt ctcaggcctc tgatgagctg      660

gagtgcaaaa tctgttacaa tcgatacaat ctgaaacaga ggaaacccaa agtgctggag      720

tgttgtcata gggtttgtgc caaatgcctc tacaagatca tagactttgg ggactcccca      780

caaggtgtca ttgtctgtcc tttctgcagg tttgagacgt gcctgccaga tgatgaagtt      840

agtagcctgc ccgatgacaa caacatcctt gtaaacttga cttgtggagg caaagggaag      900

aagtgcctgc cagagaaccc tactgagctg ctgctcaccc ccaagaggct ggcctctctg      960

gtcagtcctt ctcacacgtc ctccaactgc ctggtcataa ccatcatgga ggtgcagaga     1020

gagagctccc cgtccctgag ctccactcct gtggtagaat tttataggcc tgcgagtttc     1080

gactctgtca ccactgtgtc acacaactgg actgtgtgga actgcacgtc cctgctgttt     1140

cagacatcca tccgggtgtt agtgtggttg ctaggtttgc tctacttcag ctccttaccc     1200

ttaggaatct acttactggt gtctaagaaa gtcacccttg gggtcgtctt tgtcagcctg     1260

gtcccttcga gcctcgttat tcttatggtg tatggttttt gccagtgtgt ttgtcatgaa     1320

tttctagact gtatggcacc tccttcttaa ctgatatgca aaataagaaa ttggacacac     1380

attgccctgt ttgagtgtga agttagataa tttataattt attttctttt atgttcttta     1440

tgattagtat ccatgacatt aacaaaaccc ttggccacat gttgacttga ttggttttcc     1500

tgtaggctgg aagtaaaaat gttcatttct acttaggggt tagcaaaatt gtataagctc     1560

acacttcatg gagcactgac agcagtgagt cttcccagag aaaggacagg gtttctctca     1620

gcactgccag acagacggca ggggtgtggt gtgttatact atagggagag catggatccc     1680

tcctttcgta ttcatggatg ttctatgatg gcagttggac acaagaggaa agttgctctg     1740

agacacaaag tgtgtactcc tttcccaccc catacccctg gtattggaac accctagaat     1800

tgtcttcagg tgttttctct cttaagtcac tctctgtggt cggcgatccc attgagatac     1860

ttgtttcctc tgcccattct cccttgccaa gaggaaactc ggttccattc ccttgggtag     1920

tttcaactga ataccagttt tgccacatta ctaaggagaa tgaaaagcac tgaggaattt     1980

gcatcacagt cagcttcatg gcagaatgtg gccatttgtc cttgagacac actctttcct     2040

ccatgtctgt tttcctctct cctcagtctt atctgagaag aatggaggag aaggaacttc     2100

tcatacagcg gttattattg atgaaaacct tcatttgagt ctttccttat aacatcttag     2160

ttttggtttt tttaaaccac attgcccaat cagcctcacc ccttgtcctg aaaaggttcc     2220

atttaaatta gttgctataa attcatcaat actttttttc cctattatat ttttggttct     2280

attaggattt acttaactga atcttataac aattcgaggt gaactgtggc aatgaaaacc     2340

agaaacagtt aatgagatgc ttcagctcac agtttgaagt gctgagaacc taagtatttt     2400

gctgtacggt actgagctgt accaaaatat gatggtttag gtttatgtgc aagactttgt     2460

gttgtagtct agacaaaggg gtgggcaaga gacatgcaaa gctgaagccc tgcttgaaaa     2520

gacccttcaa ggaagtaaaa tggcaggggc agagtgcagc ttaacatgtt gctatccctg     2580

ttgtttttga gttggttttg gaatggattc aagttcttac acaatttatt ttgaatacaa     2640

gcataatcta ggtgatttga gttaatgaac ttcttttcat gatgtaggga aagttgaatg     2700

tatatatttc taagaagaat ttgtttagca gattacaagt tggcaaaata gactgttcac     2760

agaaactagg caaaaattta aaaaaacatt ctagtctcta aaacccatta ctaatgatta     2820

acattaaaat atttgtaact cttagaaagg gggcattact aagacgactt taacttgtta     2880

tgaaatcttt gttgtgtgat gcaggtacag tgcgcccatt ccaactggaa tagcagtttg     2940

attttaattg taaaactaaa cttcgggaat atgtatgccc aaagtaagta ggatgagaat     3000

agtatacatg ggatatggtc caatgaattt aagccccaag atacagctaa atacatttat     3060

gatttcataa aatctagttt agatagcatt gtgatgcaat ttccagaaat ccatttgtgt     3120

ttagagtaaa taccatgttt agaagatgtt ttgtggtttg gatttatata tttgtaaggt     3180

ttttttaaaa aaatgttcgt tttgtttgaa atgtaacatt gagtaaattg gtgagttata     3240

taatgagatt tctagaaagc tctggacatg ggtacgatgt gttttgcttc tctgtataat     3300

gtctacagtg ataaacttgt gtctccgtgt attgtggcag tctttttttc tagttaattt     3360

ggctttagag agcaatcttt gtatgacacc agaaaactct tcatgctatt gaatgataaa     3420

aagataatgc tttaatattt tattcactgt gatactattt tgtttgtcta ttaaattgtt     3480

attatttcca aatttaaaaa aaaaa                                           3505


<210>  2659
<211>  3674
<212>  DNA
<213>  homo sapiens

<400>  2659
gggcctactc tgccgccgcc gccgcccgcc cgctccagcc gccgccgccg ccgccaccgc       60

cctccaggct ccgggacccg gcccgcgcca ccgcccccgt gcgcgccccg ccgccgccgc      120

cttcgccttc gccttttgtt tcctccgctc cggcgccccc gccccggctc gcgctttgca      180

ggggacgcag cgcgcgcccc cagcgggccc gggaaaagcc gcggcgcgcg cgcgcgcctg      240

cgcggcggac ccctccttct cctccccgcg tgcgcgtgcc cttcttggct gcgcgccggc      300

gccgcctggc gggcgggagg ggaggtggca ggcgcgtttg caggaggggc gcacctcttc      360

gctcgcgcac ccccccggaa ggtagaccgg gaaggggagg cgggcgggcg gagaggagag      420

agtggcgcgc agtccagcga gggcgggggt tggctatgtg gggggtggtg caccccgcag      480

tctagacagt ctgatccggg ctgggggcgt gtacactcgg cgcacctgcg agactacaga      540

gcctcgggcc ggcacgtgtg gggagtgtgg acacgtctgc tgcgccccgc ttctcgctgc      600

tgaggggaag ggagggggcg ggcaggtgca gcggccgggc tagtgggagg gggcggcggc      660

catggagcgg gtgaacgacg cttcgtgcgg cccgtctggc tgctacacat accaggtgag      720

cagacacagc acggagatgc tgcacaacct gaaccagcag cgcaaaaacg gcgggcgctt      780

ctgcgacgtg ctcttgcggg taggcgacga gagcttccca gcgcaccgcg ccgtgctggc      840

cgcctgcagc gagtactttg agtcggtgtt cagcgcccag ttgggcgacg gcggagctgc      900

ggacgggggt ccggctgatg tagggggcgc gacggcagca ccaggcggcg gggccggggg      960

cagccgggag ctggagatgc acactatcag ctccaaggta tttggggaca ttctggactt     1020

cgcctacact tcccgcatcg tggtgcgctt ggagagcttt cccgaactca tgacggccgc     1080

caagttcctg ctgatgaggt cggttatcga gatctgccag gaagtcatca aacagtccaa     1140

cgtacagatc ctggtacccc ctgcccgcgc cgatataatg ctctttcgcc cccctgggac     1200

ctcggacttg ggcttccctt tggacatgac caacggggca gccttggcag ccaacagcaa     1260

tggcatcgcc ggcagcatgc agccagagga ggaggcagct cgggcggctg gtgcagccat     1320

tgcaggccaa gcctctttgc ctgtgttacc tggggtggac cgcttgccca tggtggctgg     1380

acccctatcc ccccaactgc tgacttcccc attccccagt gtggcatcca gtgcccctcc     1440

cctgactggc aagcgaggcc ggggccgccc aaggaaggcc aacctgctgg actcaatgtt     1500

tgggtcccca gggggcctga gggaggcagg catccttcca tgcggtctat gtggtaaggt     1560

gttcactgat gccaaccggc tccggcagca cgaggcccag cacggtgtca ccagcctcca     1620

gctgggctac atcgaccttc ctcctccgag gctgggtgag aatgggctac ccatctctga     1680

agaccccgac ggcccccgaa agaggagccg gaccaggaag caggtggctt gtgagatctg     1740

cggcaagatc ttccgtgatg tgtatcatct taaccggcac aagctgtccc actctgggga     1800

gaagccctac tcctgccctg tgtgtgggtt gcggttcaag agaaaagacc gcatgtccta     1860

ccatgtgcgg tcccatgatg ggtccgtggg caagccttac atctgccaga gctgtgggaa     1920

aggcttctcc aggcctgatc acttgaacgg acatatcaag caggtgcaca cttctgagcg     1980

gcctcacaag tgtcagacct gcaatgcttc ttttgccacc cgagaccgtc tgcgctccca     2040

cctggcctgt catgaagaca aggtgccctg ccaggtgtgt gggaagtact tgcgggcagc     2100

atacatggca gaccacctga agaagcacag cgaggggccc agcaacttct gcagtatctg     2160

taaccgagaa ggccagaaat gctcacatca ggatccgatt gagagctctg actcctatgg     2220

tgacctctca gatgccagcg acctgaagac gccagagaag cagagtgcca atggctcttt     2280

ctcctgcgac atggcagtcc ccaaaaacaa aatggagtct gatggggaga agaagtaccc     2340

atgccctgaa tgtgggagct tcttccgctc taagtcctac ttgaacaaac acatccagaa     2400

ggtgcatgtc cgggctctcg ggggccccct gggggacctg ggccctgccc ttggctcacc     2460

tttctctcct cagcagaaca tgtctctcct cgagtccttt gggtttcaga ttgttcagtc     2520

ggcatttgcg tcatctttag tagatcctga ggttgaccag cagcccatgg ggcctgaagg     2580

gaaatgaggc agctgctgtg tccccacgga aacaaccatc tggggactgc tgggaaatgc     2640

tgtgaatgcg gagggaagtg atgtttgggt tctgtagctg agagattttt attcattttt     2700

aactgccccc caaccccact ccaactcctt ctccaccacc cattctccca atggtcttta     2760

gaaatagatt ttcatctgat attctgcaga aatatcaatg agacttggta tgggacaggg     2820

gcagaaaaca ctacataggc ctccaaggca aaaccagtcc cagtttcttt aatgggaaga     2880

agctggaatt cctggtgctc aattcttagt gaccccaatc ctatacccaa atctatgata     2940

ttctgggacc tcagtgattt tggtcccctc ccacttctct agttcgtcat cctcccttcc     3000

catatccttc aaaagaacca cactagggtc tccacctact tatacaatgc ggatgcccaa     3060

ctgtttttaa ggaagccaga agcatcccat ggaccatggg gtgagtgtcc tccaagagcc     3120

ccctgagctc agccctctgc ctggagggct ccagaccttt ctgagccctg cttggaggcg     3180

agcattttca ctgctaggac aagctcagct gttgaggaca cccccacccc aaatttcagt     3240

tcttacgtga ttttaaccat tcaacatgct gttgggtttt aattctctaa ttattattat     3300

tattgttatt attttttagg accagttgta gtgaattgct actgaaagct atcccaggtg     3360

atacagagct ctttgtaaac cgcagtcaca cattagggtt agtattaaac tttgtttaga     3420

tgtaccataa ttaacttggc tagttgattg tttgaagtct atggaagaaa tagttttatg     3480

caaaatttta aaaaatgcca gtctggtcag ggaagtaggg ggtttcaatg ctgttgggaa     3540

ccaggaaggt gggacagccg gcaggtaggg acattgtgta cctcagttgt gtcacatgtg     3600

agcaagccca ggttgacctt gtgatgtgaa ttgatctgat cagactgtat taaaaatgtt     3660

agtacattac tcta                                                       3674


<210>  2660
<211>  3218
<212>  DNA
<213>  homo sapiens

<400>  2660
cttttagttt ctcttctttc taaagaaggc tcgcggagcc cggctggaga acctcaccct       60

cgccgagcct agaaccgaga gggggccacc ccaggcggtc accagcagat ttgcccgcgc      120

gttctctttc tttccaccca gttgcccttg cggccggctg taaacctgcc actaggaccc      180

ggtcggtgag atctagcctc ttgacctgag agccgagagt ggatcgctgg gctgggctaa      240

cggcgacgga gagcgcgccc tcgctgactc cgggcgcgcc cagcagtagc accgcccgcg      300

cccgcccctg gacacttgta agtttcgatt tccgatttcc gcggaaccga gtcccgcgcc      360

gcggcagagc cagcacagcc agcgcgccat ggcggacccg gaggtgtgct gcttcatcac      420

caaaatcctg tgcgcccacg ggggccgcat ggccctggac gcgctgctcc aggagatcgc      480

gctgtctgag ccgcagctct gtgaggtgct gcaggtggcc gggcccgacc gctttgtggt      540

gttggagacc ggcggcgagg ccgggatcac ccgatcggtg gtggccacca ctcgagcccg      600

ggtctgccgt cgcaagtact gccagagacc ctgcgataac ctgcatctct gcaaactcaa      660

cttgctgggc cggtgcaact attcgcagtc cgagcggaat ttatgcaaat attctcatga      720

ggttctctca gaagagaact tcaaagtcct gaaaaatcac gaactctctg gactgaacaa      780

agaggaatta gcagtgctcc tcctccaaag tgatcctttt tttatgcccg agatatgcaa      840

aagttataag ggagagggtc ggcagcagat ttgtaaccag cagccaccgt gttcaagact      900

ccacatctgt gaccacttca cccgagggaa ctgtcgtttt cccaactgcc tccggtccca      960

taacctgatg gacagaaagg tgctggccat catgagggag cacgggctga accccgacgt     1020

ggtccagaac atccaggaca tctgcaacag caagcacatg cagaagaatc ccccagggcc     1080

cagagctcct tcttcacatc gtagaaacat ggcatatagg gctagaagca agagtagaga     1140

tcggttcttt cagggcagcc aagaatttct tgcgtctgct tcagcgtctg ctgagaggtc     1200

ctgcacacct agtccagatc agatcagcca cagggcttcc ctggaggacg cgcctgtgga     1260

cgatctcacc cgcaagttca cgtatctggg gagtcaggat cgcgctcggc ctccctcagg     1320

ctcgtccaag gctactgatc ttggaggaac aagtcaggcc gggacaagcc agaggttttt     1380

agagaacggc agtcaagagg acctcttgca tggaaatcca ggcagcactt accttgcttc     1440

caattcaaca tcagccccca actggaagag cctcacatcc tggacgaatg accaaggcgc     1500

caggagaaag actgtgtttt ctcccacgct acctgccgcc cgctcttctc ttggctctct     1560

gcaaacacct gaagctgtga ccaccagaaa gggcacaggc ttgctttcct cagactacag     1620

gatcatcaat ggcaaaagtg gaactcagga catccagcct ggccctcttt ttaataataa     1680

tgctgatgga gtggccacag atataacttc taccagatcc ttaaattaca aaagcactag     1740

cagcggtcac agagaaatat catcacctag gattcaggat gctggacctg cttcccgaga     1800

tgtccaggcc actggcagaa tcgcagatga tgctgaccca agagtagcac ttgttaacga     1860

ttctttatct gatgtcacaa gtaccacatc ttctagggtg gatgatcatg actcagagga     1920

aatttgtctt gaccatctgt gtaagggttg tccgcttaat ggtagctgca gcaaagtcca     1980

cttccatctg ccttaccggt ggcagatgct tattggtaaa acctggacgg actttgagca     2040

catggagacg atcgagaaag gctactgtaa ccccggaatc cacctctgtt ctgtaggaag     2100

ttatacaatc aattttcggg taatgagttg tgattccttt cccatccgac gcctctccac     2160

tccttcttct gtcaccaagc cagccaattc tgtcttcacc accaaatgga tttggtattg     2220

gaagaatgaa tctggcacat ggattcagta tggagaagag aaagacaaac ggaaaaattc     2280

aaacgtcgac tcttcatacc tggagtctct ctatcaatcc tgtccgaggg gagttgtgcc     2340

atttcaggcg ggctcacgga actatgagct gagtttccaa gggatgattc agacaaacat     2400

agcttccaaa actcaaaagg atgtcatcag aagaccaaca tttgtgcctc agtggtatgt     2460

gcagcagatg aagagagggc cagagtaagt gttctgaagc agctgtttgc tgacagatgc     2520

ttgagatgtt catgccctgg gctcatcaag tcactcgtga atctggagcc tgttttcctg     2580

aaaagttcct gtttgcatta ctctgcagtt tccatttgca ttatcgatga gtaagatgct     2640

tgttaagcag catggtgtga ctgaaaggat actagatcgg aaaatgaatt ttctttctga     2700

aagggaagtc tgagcgagtc tcctaaatac tctgggcttt agcttctcca gctgtgaaga     2760

gctggattga tgcagtacac ctaaggaata atcatatata ctgggttttt gttttgctgt     2820

ggattctttt tttttttttt ttttttagag ggggtctcac tttgttgccc aggctggtct     2880

tgaactcctg agctcaagtg atcctcctac ctcagtctcc caaagtgctg ggattacagg     2940

catgagccac cgtgcctggc tttgctgtgg attcttttgg gtgtcttttg ttttcctaca     3000

cgatttatag aggatgaggg gcggagaaag agatagaaaa aagggatgag ctagctgtta     3060

gagcaagggt tttggtgaga gataatattg attgaaggga ttttaaagga aatgttgctg     3120

tgggggattc attgtaactc tccttgtgaa ctgctcagta aactctacat tgttcatgaa     3180

caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                             3218


<210>  2661
<211>  4621
<212>  DNA
<213>  homo sapiens

<400>  2661
gctcagaaac tgccagccca gaccacaggc tcagaggctg aagcaggagg aaggaaggac       60

tggaaggaaa aagagacagg ttagagggaa agaggcttgg gaagaaaaca gcagaaaaga      120

aactgctcat tacacttaca gagaggcaag taacggtgga gatgaggaca gagggaacca      180

agactctgaa agacaaaaaa tacaaataga gcgaaagagg aaaaaaatgt caagaagaac      240

atccatccgg agaaatgaag agaatgaaag ttttaagctg cagagccgtt ctgtgctttt      300

ccggcacaaa attatatcgc tgattttaag cccttttgca tttgccagcc gttgacatta      360

agaggcatgt ttaacggtgc caacagcatc tccttttcct tctcctcttc ctcttcttct      420

tcttcctcct cctcctcctc tttttcctcc tcctcgttct cctcccatca gcaagaagac      480

aaaccgagga cagtcttgaa atatcgaaat ttcctctttg ggatttgcca gcgccaagac      540

tgtcggaata aaggacgctg actattgtat tattgttatt ttattaatta gtcagtggaa      600

agattacaga tgaggaaagg ggacgcctgt cacccttcct gtgctaagat ttaaaaaaaa      660

atgaggctgg attgcgggaa gctctaaaat gaagcaaaag gagtaagatt tttaaagaca      720

gaaagccaca ggagccccca cgtagcgcac ttttatttgt attttttcag attttttttt      780

gtttcgtggt ggtgggggag gtgattgggt ggctgactgg ctgcgggaag ctacttcctt      840

tccttttgga gatgattgtg ctattattgt ttgccttgct ctggatggtg gaaggagtct      900

tttcccagct tcactacacg gtacaggagg agcaggaaca tggcactttc gtggggaata      960

tcgctgaaga tctgggtctg gacattacaa aactttcggc tcgcgggttt cagacggtgc     1020

ccaactcaag gaccccttac ttagacctca acctggagac aggggtgctg tacgtgaacg     1080

agaaaataga ccgcgaacaa atctgcaaac agagcccctc ctgtgtcctg cacctggagg     1140

tctttctgga gaaccccctg gagctgttcc aggtggagat cgaggtgctg gacattaatg     1200

acaacccccc ctctttcccg gagccagacc tgacggtgga aatctctgag agcgccacgc     1260

caggcactcg cttccccttg gagagcgcat tcgacccaga cgtgggcacc aactccttgc     1320

gcgactacga gatcaccccc aacagctact tctccctgga cgtgcagacc cagggggatg     1380

gcaaccgatt cgctgagctg gtgctggaga agccactgga ccgagagcag caagcggtgc     1440

accgctacgt gctgaccgcg gtggacggag gaggtggggg aggagtagga gaaggagggg     1500

gaggtggcgg gggagcaggc ctgccccccc agcagcagcg caccggcacg gccctactca     1560

ccatccgagt gctggactcc aatgacaatg tgcccgcttt cgaccaaccc gtctacactg     1620

tgtccctacc agagaactct cccccaggca ctctcgtgat ccagctcaac gccaccgacc     1680

cggacgaggg ccagaacggt gaggtcgtgt actccttcag cagccacatt tcgccccggg     1740

cgcgggagct tttcggactc tcgccgcgca ctggcagact ggaggtaagc ggcgagttgg     1800

actatgaaga gagcccagtg taccaagtgt acgtgcaagc caaggacctg ggccccaacg     1860

ccgtgcctgc gcactgcaag gtgctagtgc gagtactgga tgctaatgac aacgcgccag     1920

agatcagctt cagcaccgtg aaggaagcgg tgagtgaggg cgcggcgccc ggcactgtgg     1980

tggccctttt cagcgtgact gaccgcgact cagaggagaa tgggcaggtg cagtgcgagc     2040

tactgggaga cgtgcctttc cgcctcaagt cttcctttaa gaattactac accatcgtta     2100

ccgaagcccc cctggaccga gaggcggggg actcctacac cctgactgta gtggctcggg     2160

accggggcga gcctgcgctc tccaccagta agtcgatcca ggtacaagtg tcggatgtga     2220

acgacaacgc gccgcgtttc agccagccgg tctacgacgt gtatgtgact gaaaacaacg     2280

tgcctggcgc ctacatctac gcggtgagcg ccaccgaccg ggatgagggc gccaacgccc     2340

agcttgccta ctctatcctc gagtgccaga tccagggcat gagcgtcttc acctacgttt     2400

ctatcaactc tgagaacggc tacttgtacg ccctgcgctc cttcgactat gagcagctga     2460

aggacttcag ttttcaggtg gaagcccggg acgctggcag cccccaggcg ctggctggta     2520

acgccactgt caacatcctc atagtggatc aaaatgacaa cgcccctgcc atcgtggcgc     2580

ctctaccagg gcgcaacggg actccagcgc gtgaggtgct gccccgctcg gcggagccgg     2640

gttacctgct cacccgcgtg gccgccgtgg acgcggacga cggcgagaac gcccggctca     2700

cttacagcat cgtgcgtggc aacgaaatga acctctttcg catggactgg cgcaccgggg     2760

agctgcgcac agcacgccga gtcccggcca agcgcgaccc ccagcggcct tatgagctgg     2820

tgatcgaggt gcgcgaccat gggcagccgc ccctttcctc caccgccacc ctggtggttc     2880

agctggtgga tggcgccgtg gagccccagg gcgggggcgg gagcggaggc ggagggtcag     2940

gagagcacca gcgccccagt cgctctggcg gcggggaaac ctcgctagac ctcaccctca     3000

tcctcatcat cgcgttgggc tcggtgtcct tcatcttcct gctggccatg atcgtgctgg     3060

ccgtgcgttg ccaaaaagag aagaagctca acatctatac ttgtctggcc agcgattgct     3120

gcctctgctg ctgctgctgc ggtggcggag gttcgacctg ctgtggccgc caagcccggg     3180

cgcgcaagaa gaaactcagc aagtcagaca tcatgctggt gcagagctcc aatgtaccca     3240

gtaacccggc ccaggtgccg atagaggagt ccgggggctt tggctcccac caccacaacc     3300

agaattactg ctatcaggta tgcctgaccc ctgagtccgc caagaccgac ctgatgtttc     3360

ttaagccctg cagcccttcg cggagtacgg acactgagca caacccctgc ggggccatcg     3420

tcaccggtta caccgaccag cagcctgata tcatctccaa cggaagcatt ttgtccaacg     3480

aggtaaggct gaagcgaaag gaccaccatc tctcatctcc tccatcagaa agcctcctct     3540

agcccggccc ttgtatctct ggtgcactgt atctattttt aggatattag cttatgtgta     3600

tcgttgtggg agcagagatg ggcggtcacc ttctcccact ccttcgtgtg taacctaact     3660

ttcgcgttgt tccacccttt cacatttatt ttcattccgt ccccttggta ctttgccacc     3720

ttggagctcc ctcctttgct cttccatcct gtcagtcctt tcccttctca gtaacctggg     3780

catgaaggga aactgcgtga agggagaggg aaatgtggag gagggactta ctttctagca     3840

ctggcaaagg tcttttttct ttgcgtctgt cccaggcatt aataaagttg gctctatttt     3900

gctttgttta acgatgcttt tagtcgcgtg tacaagtaag ctatagattg tttaacttta     3960

cacagttgtc taacctcgaa ttcatgtttt agtgaacaag ttaccagatc cttctcctct     4020

gaactcgggt tgcaaaaaaa gccttcagtt cggctctgga cagcatttac agacgctctt     4080

gaagccgagc gcccacacag tgtgaatttg aatgaagctg cgttggcaca aacccctgtt     4140

aagagtaaac taacgaaagg cttaaacaat tgttgtctta aatatatctt tttagctaat     4200

aatcaccttc ttgccactgt tttggataaa tcacgctgtt ggctttcttc ataaaagaat     4260

ttggcttgtc aattctgact tctttttaaa aggatggaga agtgacaaag tcggagggtg     4320

ggggttgggg ggagaacaaa gttggtttat gtgaaagaaa gcttggaccg gaaaggtgtg     4380

tgggtggtag aggtggggag gcgaatgcag agggcctttg gaggggaaaa gaatgggggt     4440

ggtggggggc gggcaggatt atgaactcct ttcctggcag gttattttat ttgagtctta     4500

gatattatta attgactttc atgaatattt gtacagctca tttgtatctt aagcacattt     4560

tgaaaataaa caacaacata attccaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     4620

a                                                                     4621


<210>  2662
<211>  4278
<212>  DNA
<213>  homo sapiens

<400>  2662
agagggaaaa taattcttca aaaaagaaaa gtcagtcttc tcctctccag tccgtggaaa       60

atccaacggg gacgttgaca agagggtatt tttaggaaac acatccaaat atacagggta      120

agagtgaatg tgagaaaaaa aaaagttgtg ggttgtagaa gttatcaagt gggatttgcg      180

gcgctctctg caggaaacgc gaacggctcc agttcaaagc cacatgcacc aacgtgacat      240

ataagccatt aaaatatcat cctgacggct catttctgct tcatcataca ttccctaact      300

gcttcctgaa agctggaaaa ggagaagtga aggatgaccg cctcgctgga accacaaaag      360

agaggcttgg aggggtttgt ggtcccctct cagccacccc gaaatgatgt gcagaaatga      420

ggcgatcctg gcaacaggtg gagtggggct caaagtcaga aaatgagata caagacatcc      480

ttggtgatga ggaaacgatt acggctttac cgaaacactc ttaaagagtc aagtagcagc      540

tctggacacc atggccccca gctcaccgcc gcctccagcc cctcggtgtt cccgggcctc      600

cacgaggagc ctccccaggc ctcccccagc cgtcctttga atggactcct gcgtctgggg      660

ctccctggag acatgtacgc gcggccggag cccttcccgc cagggcctgc ggcccgcagc      720

gacgccctgg cagctgccgc agccctgcat ggctacgggg gcatgaacct gacggtgaac      780

ctcgctgcgc cccacggtcc tggcgctttc ttccgctaca tgcgccagcc catcaaacag      840

gagctcatct gcaagtggct ggcggccgac ggcaccgcga ccccgagcct ctgctccaaa      900

actttcagca ccatgcacga gctggtcacg cacgtcaccg tggagcacgt cggcggcccg      960

gaacaggcca accacatttg cttctgggag gagtgtccgc gccagggaaa gcccttcaaa     1020

gccaaataca aacttgtaaa tcacatccgc gtgcacacgg gcgagaagcc cttcccttgt     1080

cctttcccgg ggtgtgggaa ggtctttgct agatcagaaa atctcaaaat acacaaacga     1140

actcacacag gcgagaagcc cttcagatgc gagttcgagg gctgcgagcg gcgcttcgcc     1200

aacagcagcg accgtaagaa gcattcgcac gtgcacacta gcgacaagcc atacacgtgc     1260

aaggtgcggg gctgcgacaa gtgctacacg caccccagct cgctgcgtaa gcacatgaag     1320

gtgcacgggc gctcgccgcc gcccagctct ggctacgatt cggctacacc gtctgccctc     1380

gtgtcgccct cgtcggactg cggccacaag tcccaggtgg cctcctcggc ggcggtggcg     1440

gcgcgtaccg ccgacttgag cgaatgatgt ccaccgcgtt gctcgcaagg taatctcgct     1500

ccgcgcagct gagcgccccg catctcgcgc ctgctacatc aaagggcccg cgcacaaagc     1560

agtgtttctt cgccacggtg catcttcatg gtaagttagg atttctatgg caatgtgcaa     1620

gtcgcactga aatcctgaaa ggccaagcct ggagcccgtc caggcttttc attaaggaca     1680

taatatttac gtctaacaga ccttttttct tgtgtataca agtatatatt tttgtttgac     1740

gcggactaaa tcattttcat ttaatttccg gtaaacaaaa cccacgcgaa tgggcacttg     1800

tacccgatca taataaaaat ggataataat gtgaaggaag aaaagagccg cttgaatcgc     1860

cgctcagccc cctttgtttc tgctttctgc ggtgatcaga gggcgcgttt gggtttgatg     1920

gcgagtttct aaaggcgagg aaatggtttg taagagggga aagaaaagga gaaaggtcta     1980

atcaagctcg ggttgttcaa agagtcgggt tttggggttg aaagtgtgag tttgacggtg     2040

catcagcatg ccgcgttagg ctcgccatgg aaatacgcgc ggggagcggc cgcttcaaag     2100

gcggcacact tcactacaga cactctatta agatacattt gcgctgacct ttgctttcac     2160

gccatttaat actgtcactg cgctctccag tatatacttc ctttctagaa cccgacttgc     2220

ccacgtttag gggttcactc tgcaccctga tgtgggaggc tttggcgcag gggacacttt     2280

caggaaaggg aggagcacaa ggactctgtg catcttgact gcaccccaaa gaggctccag     2340

gatcaggagt gaaagatttt aaagcagcct ccgaagctta acaaatgagc attccaagct     2400

cagttttgtg caaatcgcct ttctgactct tgagtaggat ggaggcttaa atttaatggc     2460

gacttggggg gaagggagcc accctggggg agtctgagga gttcagactg tgcccttggg     2520

aatttccact ctggctttcc gtgccactct tcttcctttc catcccaaaa gtctcttgcg     2580

gcccctgaaa cttgtttctt tctaaggcag ggtgtgtggt acccttaggc ctggactagt     2640

cctagatgca aactcaagag cccaaggcca aggggatgtg gggaagatgg caggaaagtt     2700

agaagtccat gttcccttaa ttgtcttgtt gtttatttta tccaagtacc ccagtgaata     2760

ggggaaaaat aaacacagtg aaaaaaaaaa tcaaacagtg gagtcttctt tagtgccagt     2820

ccttgtggtt gaataaaaag gatggtccgc tttctattga gctgagaaat ctttgaagtg     2880

ggagttatta tctgagacat tcctgcttgt cgtcctaaca acgctgatga aacgtaaaag     2940

gttctttgtc agcgatttgt tctcctctct gtcaaactcc ctctgccccg ttagtttcaa     3000

accgtttcta aagagataaa aatcaaactt cttttaaaac aatatccaca cactgcatca     3060

atacataact ttaggtctaa gtcttgctaa gggataaaca aaagcaatgc ctagacatca     3120

gggtcagggc ctggtctggt gaagtatgca gaagttgggg ggccctcggg acaagctttg     3180

ggacatgagg aaaagaatgc agagagggtg caagcagaat acatacccta agtccataat     3240

tgtgtttctg cttctttctg ctctggtttg cattcaatca gcccaagttg ggtcacatag     3300

atgggtttcc tttgggtacc cctcaggctc ctaatattct tgcccaggat ccttggaact     3360

taagaatgca gccaagcaat tgttaatatc tcctgctcct tcaaagccac ctctgctaaa     3420

aatagaccca ttgtgtgttt cttctcacta gcagcaatca acaagccctt tctgccgtta     3480

ataagaagga gaatagctga aggagagaga tattttatta atttcctgtt tccttcagaa     3540

tcttggcaat tgaagtttag aaggtttggt ctacaacaca gtgatcgaaa atgcatgtaa     3600

atgcccatcc ttcccttcat tcacgtgtga agttgttcat tttatattgt gcccagcaaa     3660

gaaactttca cccagttcag gtttccccaa aactcctgtg gtggttttaa aggtggttta     3720

aataaataag gatgtgctgg tccccctact ctgtgtgtgc tgaataaatg gcttgtaaag     3780

aagtttttcc aagctgtaac ccatgctgtt attatagttg ctgcaaaatg ttcttcctga     3840

tattgatttt atttgttaac tgaaggtctc catatgtttg tttatattgc taatttatga     3900

gaaaatgtaa taattgcaat gaatgtgaat tatacagaca ggcaaacatt ttgtaatcat     3960

aattcacata tacacaaaag cctggctgaa atctttagac tatttgtacc ctctctaccc     4020

acactgtttg tgatttatca tctgtctctt tagtgtcagt taaattatga actaacttga     4080

aaataaaagt tgtttgactg aaagtgattg ttgaatgaac aacaaagttg aaagccatgg     4140

cttgatcttg taaatatata aatgtaaatg atattaaatc tgtgattcct tttccctcca     4200

aaggcttttg tgtacatggc gctgcatttg gctattttct ttggaaataa ataatgtgat     4260

gtttctcttc ctcttttg                                                   4278


<210>  2663
<211>  2961
<212>  DNA
<213>  homo sapiens

<400>  2663
ggtgactctc ggagcgggag gcggaggctg aggcggccgc tcctgctgct gctactgccg       60

ccgccgcagc ggctgctcgg gctgagcacg ccccggaaca ggccgccgcg cgctgcgcgc      120

cggacccgct gcccctgccg gcccggccgg gtcgggcggc ccagggcggc accttcctac      180

ttctgcccag ccacagccct cccctcacag ttgagcacct gtttgcctga agttaatttc      240

cagaagcagg agtccccaga gccaggcagg gggatgaacc gcgagggagc tcccgggaag      300

agtccggagg agatgtacat tcagcagaag gtccgagtgc tgctcatgct gcggaagatg      360

ggatcaaacc tgacagccag cgaggaggag ttcctgcgca cctatgcagg ggtggtcaac      420

agccagctca gccagctgcc tccgcactcc atcgaccagg gtgcagagga cgtggtgatg      480

gcgttttcca ggtcggagac ggaagaccgg aggcagtagc tgcaaagccc ttggaacacc      540

ctggatgctg ttgagggcca agagatctgt gtggctcctg ggccggctga gtggcagcag      600

ccccccttgc cccacctccc ccttccccta cccaaccctg ccctgcccca ccccacctca      660

cagctactca gtggggctgg catcaaggga gacaccagtg gtgcgtttat aattggctta      720

aagggatgga cttgtgattg gctgcaggaa gaaacttttt tattttttaa atcttgacca      780

acagaaacct tttattttta tttctgactc ttatttttta aaaaatttgc gcctcggtat      840

ctggcttccc tggaagctct ccgagctctg gtgctttagt taggtcattt ttttagaaat      900

gtgaagaggt ctgattggct gcttaaactg gaaaggatct gtgattggct ggttaatggg      960

aaacggtttt tttctttggc tgcaggtgtt ctgctgatat caacagcttc cctattttga     1020

atgcagaaaa cagggtctgg gacattagtc gttatatttg acttgaaaag aaagaaacca     1080

agtgcgcttt gcaatattta ttacacaaag aacttgctgc tgccttcaca tttggggttt     1140

gtgtttgatt ggctttcgat gcgtgtgttt ggtttcccat tggttcacct gtgactcctg     1200

ttgccatgga ttcacccccc tctgctgccg gctctgggcc tgagggtcca cctggagagt     1260

acatttgctt taatgagtgc acctgcctcc accagcaagg ggaccccgag aaccctgagc     1320

agggtccaca gctggaaagt tgggcccctg aggagctttg tgtcgtcttg aacgagcagc     1380

ccagggccta gaggtaaccg ttaggcggga tttatgtgca ctgcctgcat gagctggcaa     1440

ccagccagcg tcccttggtg agaaagggat tgctgaggca ccgtccaggc cccaccggcc     1500

aggccgcgcc cagcagaggc gtactaccca gctctgtcct cttggccatc cttctgtgta     1560

ccacttcctg aggcctcatt ttgggggtca tcttggaaag gggaggagct tctcccagtg     1620

tgagacccca aagactctgg aggtcatctg gcggaggtct ctgggagccc agaacccaca     1680

taaaagcccc agcttggctc acaaggccca ggagacctcc agctaaacac caacccctga     1740

cctaccccag ccaggctcct acctgtctgc tgccagcaca gtaggtcccg gccagctctg     1800

gagttctctc atcggaggcc catgccctcc actccactgc ctttggaagg gtctctctcc     1860

aggtcagcct ggaagggaca gtatcgtttg tttatgaaat gccactggga cagctggctg     1920

ggccttcacc aagcaagtcc cttcagactg gcccttaagc caaactcagg cccagaattg     1980

cagttcagaa tggcagtcct ggaggcaggg ggtgaggggc aggtctagtg ttcctgcacc     2040

aaacctaagt ccttccacct gccaccccct tccctgggag ggaggtggtc ctcctatctc     2100

cctggctcac tggcaggtgt gggatctggg gagagcggct ggagaaagat gcagtcctca     2160

ggaagggggc cgccaccctc ccctatgctg gtagatgctg aggcccctag gtgcccaggg     2220

ccagtgggac cctctcagaa ccaaatcttt cccctttctc ggggcttggg gctcgggccg     2280

taggggctcc tgagtgtcat gaagtgcaca ggagccaaat gaccgagccc tggagagccc     2340

catggtgggt aggtggttcg tgctgtgctc tggcaccatc agcctgttcc agaaggagga     2400

ttcgagcatc aggctaagac cctgtgtcct ccaccatgca ctcaccccta gccctggtta     2460

gctgacagtc agctgtgggg aacacagcta caaccctacc ctggcaggga cctgagagca     2520

tctcaggagg ggcagcgcat gtgtgcatgt gctgtgtgag tgagcacacc cgtgtgcaca     2580

ctcatacaca tgtgcacaca cacgcactct ccccgctcag gggcctggag gtctggctga     2640

gcccctgggg aaaggtgagt tctttcatct ccctcctcca ggtcggagtg cctggagtca     2700

ggtgtcgagg ccacattgct ggctgccccc tctttgtagc tcctataaag ggcccacacc     2760

tggtggatac ctggttgagt gtgtggtctc tgccccagcc tgtccttgtc acgatcacag     2820

gccttgcttt tgtaacaatg atgaccccgg cctgtctcat cttctgaaga ggaaaagtca     2880

aagtgttgct gtggctccat atttcaacta aaaatatatc tgttggagaa agaaattaac     2940

aataaagaat tttcataggt t                                               2961


<210>  2664
<211>  2471
<212>  DNA
<213>  homo sapiens

<400>  2664
agtccctgcc ctcccctggg gagggtgagt cacgccaaac tgggcggaga gtccgctggc       60

ctcactccta gctcatctgg gcggcggcgg caagtgggga cagggcgggt ggcgcatcac      120

cggcgcggag gcaggaggag cagtctcatt gttccgggag ccgtcaccac agtaggtccc      180

tcggctcagt cggcccagcc cctctcagtc ctccccaacc cccacaaccg cccgcggctc      240

tgagacgcgg ccccggcggc ggcggcagca gctgcagcat catctccacc ctccagccat      300

ggaagacctg gaccagtctc ctctggtctc gtcctcggac agcccacccc ggccgcagcc      360

cgcgttcaag taccagttcg tgagggagcc cgaggacgag gaggaagaag aggaggagga      420

agaggaggac gaggacgaag acctggagga gctggaggtg ctggagagga agcccgccgc      480

cgggctgtcc gcggccccag tgcccaccgc ccctgccgcc ggcgcgcccc tgatggactt      540

cggaaatgac ttcgtgccgc cggcgccccg gggacccctg ccggccgctc cccccgtcgc      600

cccggagcgg cagccgtctt gggacccgag cccggtgtcg tcgaccgtgc ccgcgccatc      660

cccgctgtct gctgccgcag tctcgccctc caagctccct gaggacgacg agcctccggc      720

ccggcctccc cctcctcccc cggccagcgt gagcccccag gcagagcccg tgtggacccc      780

gccagccccg gctcccgccg cgcccccctc caccccggcc gcgcccaagc gcaggggctc      840

ctcgggctca gtggatgaga ccctttttgc tcttcctgct gcatctgagc ctgtgatacg      900

ctcctctgca gttgttgacc tcctgtactg gagagacatt aagaagactg gagtggtgtt      960

tggtgccagc ctattcctgc tgctttcatt gacagtattc agcattgtga gcgtaacagc     1020

ctacattgcc ttggccctgc tctctgtgac catcagcttt aggatataca agggtgtgat     1080

ccaagctatc cagaaatcag atgaaggcca cccattcagg gcatatctgg aatctgaagt     1140

tgctatatct gaggagttgg ttcagaagta cagtaattct gctcttggtc atgtgaactg     1200

cacgataaag gaactcaggc gcctcttctt agttgatgat ttagttgatt ctctgaagtt     1260

tgcagtgttg atgtgggtat ttacctatgt tggtgccttg tttaatggtc tgacactact     1320

gattttggct ctcatttcac tcttcagtgt tcctgttatt tatgaacggc atcaggcaca     1380

gatagatcat tatctaggac ttgcaaataa gaatgttaaa gatgctatgg ctaaaatcca     1440

agcaaaaatc cctggattga agcgcaaagc tgaatgaaaa cgcccaaaat aattagtagg     1500

agttcatctt taaaggggat attcatttga ttatacgggg gagggtcagg gaagaacgaa     1560

ccttgacgtt gcagtgcagt ttcacagatc gttgttagat ctttattttt agccatgcac     1620

tgttgtgagg aaaaattacc tgtcttgact gccatgtgtt catcatctta agtattgtaa     1680

gctgctatgt atggatttaa accgtaatca tatctttttc ctatctatct gaggcactgg     1740

tggaataaaa aacctgtata ttttactttg ttgcagatag tcttgccgca tcttggcaag     1800

ttgcagagat ggtggagcta gaaaaaaaaa aaaaaaagcc cttttcagtt tgtgcactgt     1860

gtatggtccg tgtagattga tgcagatttt ctgaaatgaa atgtttgttt agacgagatc     1920

ataccggtaa agcaggaatg acaaagcttg cttttctggt atgttctagg tgtattgtga     1980

cttttactgt tatattaatt gccaatataa gtaaatatag attatatatg tatagtgttt     2040

cacaaagctt agacctttac cttccagcca ccccacagtg cttgatattt cagagtcagt     2100

cattggttat acatgtgtag ttccaaagca cataagctag aagaagaaat atttctagga     2160

gcactaccat ctgttttcaa catgaaatgc cacacacata gaactccaac atcaatttca     2220

ttgcacagac tgactgtagt taattttgtc acagaatcta tggactgaat ctaatgcttc     2280

caaaaatgtt gtttgtttgc aaatatcaaa cattgttatg caagaaatta ttaattacaa     2340

aatgaagatt tataccattg tggtttaagc tgtactgaac taaatctgtg gaatgcattg     2400

tgaactgtaa aagcaaagta tcaataaagc ttatagactt aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa a                                                          2471


<210>  2665
<211>  4210
<212>  DNA
<213>  homo sapiens

<400>  2665
ccgcccgccg ccgccgcagc tcccgacgcc gccgcccccg ccgggtgcct aagcaggccc       60

ggcgcggccc caggacttgg gaccctggag gactgacgct gctggcctgg gcgtcccctt      120

ccgctgagcc atggcgactc ccgacgtgag tgtgcacatg gaggaggtgg tggttgtgac      180

aactccggac actgcagtgg acggcagtgg tgtggagggg gtgaagaccg tgttggtgac      240

gaccaacttg gcccctcacg ggggcgacct gacggaagat aacatggaga cagaaaatgc      300

agcggcagca gctgccgcgg ccttcacagc ctcctcccag ctcaaggaag ccgtgttagt      360

gaagatggct gaagaggggg agaacctgga agctgagatt gtgtacccca tcacctgtgg      420

agacagcaga gccaacctca tctggaggaa gtttgtgtgt cccggcatca atgtgaaatg      480

tgttcagtac gacgagcatg taatcagccc aaaggaattt gtgcacctgg ccgggaagtc      540

caccctgaag gactggaaga gagccatccg catgaacggc atcatgctca ggaagatcat      600

ggactccggg gaactggact tctaccagca tgacaaggtc tgctccaaca cctgccgcag      660

cacaaagatt gacctctcag gagcccgtgt gtccctgagc agccccacgt cggccgagta      720

cattcccctc acgcccgccg cagccgacgt gaatgggtct cctgcgacca tcaccataga      780

gacctgtgaa gaccctggcg actggaccgc ggccattgga gatgacacat ttaccttctg      840

gcgggggctg aaggacgccg gcctgctgga cgaggtcatc caggagttcc accaggagct      900

ggtggagacc atgagaggcc tgcagcagcg ggtccaggac cctcccctgc agcttcgaga      960

tgctgtactt ctcaacaaca tcgtgcagaa cttcggcatg ctggacctgg tgaagaaggt     1020

gctggccagc cacaagtgcc agatggaccg ctcgcgggag cagtacgccc gggacctggc     1080

agccctggag cagcagtgtg atgagcatcg tcgccgagcc aaggagctga agcacaagtc     1140

ccagcacctc agcaacgtgc tcatgacgct gacgccggtc tccctgccac cgcctgtgaa     1200

gcggccccgg cttgcacgtg ccacatcagg accggccgcc atggcctcgc aggtgctcac     1260

ccagtctgcc cagctggcgc ttggcccggg cgtgcccgtc ccccagctga ccagcgtgcc     1320

ccttggtaaa gtggtgtcca ccctgccgtc caccgtcctg ggcaagggtt cccttcaggc     1380

gccccccgcc agctccccgg cctccccgct gctcggggga tacacagtct tggcctcttc     1440

cggctccacc taccccagca cagtggagat ccacccggac gcgtccagcc tcacggtcct     1500

gagcacggcc gccgtgcagg acggtagcac ggtgttcaag gtggtcagcc cgctacagct     1560

gctcacgttg cctggcctgg gccccaccct gcagaacgtg gcccaggcct cgcctggctc     1620

cagcacaatt gtgacagtgc ccgcaggggc tgcccccggg cctgaggagc acacggccac     1680

cattgaggtg gctgccatgg cagaggacca cgagcggaag tagccgacag gagggcgagg     1740

cccctgggac ggacagggct ggctgtctct cagccgcggc agcagggagc gggcagaggc     1800

cgcagggctg gctcgggcag gtgggtcacg tggtctgcag aaccaaagag aggaatcgcc     1860

aaaacaaatc acgagaagag agaaggggac agaacagcga gagcaacctg gaaaatcggt     1920

cttcaggtcc cacgtttcct cccccttttt tcttgggaaa tatatttttc catctgttgc     1980

ttattaatac tgtttacaca ttgggccttg atcaggagcc aggtgggcgg gggctagggg     2040

gagcctgggt gcagcagaga cagaggaagc agagccaggt gccgagcgcg accctgcagg     2100

tgctggacgc ggtgcagcag gtcacgaggc ccccatgtct gcacccagcc aggtccctgg     2160

ggacgttact aactcatgac ttgggagcta agcccaagtg tgaaacctct ggatcctatg     2220

gatttggttt cttcccacag ttttctgtag gtttagtgtg gctggcgccc cgttctcctc     2280

cagttgggaa catgcacccg gagcttgggg tgcagatcct gatgggtgcc tgcctccccc     2340

gcccccagcc ggtgctcagg tggcccaggg gccgcacaga cgaggcgtgg tccaggcatt     2400

gttgcacatg tactgagggt gtttttaagt gaattgctta gtaggcttct aggaagagtc     2460

agatttatag cattttcaac caaaataatg gtgagtgcct aggcttcccg agttagctct     2520

ttgggtggcc cctgagcccc tgtgagtgca cttgaccggg tgcggaggtc ctgggcagcc     2580

tgtccctgag ccggcccctc ccaggggtct gagatccatg aggtgtgtcc ctagggcttc     2640

agtcctgggg cagaggcata aacagaacca gtcactatgg aggtcgagga ttcccatgtg     2700

ggcccttcag cttgggctgc ttggccacgg aacagccctt ggctccctgg cccccggccc     2760

ccatgcagcc cctgggctgg cccttggtgg tctctgtcca agggagagcc cctgggtgtt     2820

caggaggctg ccccgggtgg gctgctcagg gcagctgccg aaggtggagc ccagagcctg     2880

tctggaaggg ctgtctgtgg ctgtcctgag acctggcctt ggactcacaa ggaagaccag     2940

gctgaggccc ctccaggcca gggtcctggg gcaggcatct cagggagcag ccagcccagg     3000

cctcctgccg tctccaacag ggcatgtccc gggaggaccc tgagtgccag attcccctgg     3060

acgctcctgc tgattctgtc ggcagttgaa ggcccgtctg aggccccgca atgcgagggt     3120

cctgtgtccc acttcactgc tccgaaggga actggctggc tgtccgtcca gtgagcggcc     3180

cagaccccac ctctgcgcca ttgtcaccag ggccctgtcc tggctgccct cacccatgtc     3240

aagctactga ggctgtgtct tgtttgtttt ctctgttaca tttttgtttg ctgttgtcac     3300

agtcagctgg tttcggcgtg atgttgatct tttgatgtac atactccgtt ttaaactcat     3360

ttccactcta gttgagttct gcagcatgca gcggtatgac cctacggggg tcaggagagc     3420

cctgcggccc ccacccacca gctcagaacc tgtcactaat acagctgcct gtgaccctgg     3480

gacccgcaac cttccagctg cttccctttg tcaaagtcac gagtgcgtct gccttgacag     3540

ccctcgtcaa cagaacttcc agtgggttgt gggttcattt cctttctttt taagaacagg     3600

gttgggacct tttctgcccc tgccccttag ctactgaggc atagggagag gaagttaatt     3660

tcagagccat acaaaaataa gccacaacca gcttcagaat taattcccaa tcccccattc     3720

caccagggct gggagcccat tcccagtgct tcccaaggcc ctcggggaca tctaccgcca     3780

acccagctgc ttctggcagg ggctccaagc cccagcgtgg ggaagggccc tggagaagcc     3840

ctcatcctca tgggaaccac actgcagtgg gtggggaagg ttgttgtcag caccgccccc     3900

ggctcctcca ggtcctgctg gctcctcggg ggcagggttc cctggacctc ccagttctgc     3960

gccttggggc cagccagtac tcagagagga ggaccttctc aaccacgtac agaacacggg     4020

ttttcatggc tgcctttggt ttggttttct gagaagatag gattggattg gattttgcag     4080

agggtgagaa cttctctgtg cctgctcaga ggcgccctag ggaagggcca tgtttgagtt     4140

ttgctttgta tgttgttttg caagtatctg cctggtactt tgatttaaaa taaaaacaat     4200

tttcatagtt                                                            4210


<210>  2666
<211>  4210
<212>  DNA
<213>  homo sapiens

<400>  2666
ccgcccgccg ccgccgcagc tcccgacgcc gccgcccccg ccgggtgcct aagcaggccc       60

ggcgcggccc caggacttgg gaccctggag gactgacgct gctggcctgg gcgtcccctt      120

ccgctgagcc atggcgactc ccgacgtgag tgtgcacatg gaggaggtgg tggttgtgac      180

aactccggac actgcagtgg acggcagtgg tgtggagggg gtgaagaccg tgttggtgac      240

gaccaacttg gcccctcacg ggggcgacct gacggaagat aacatggaga cagaaaatgc      300

agcggcagca gctgccgcgg ccttcacagc ctcctcccag ctcaaggaag ccgtgttagt      360

gaagatggct gaagaggggg agaacctgga agctgagatt gtgtacccca tcacctgtgg      420

agacagcaga gccaacctca tctggaggaa gtttgtgtgt cccggcatca atgtgaaatg      480

tgttcagtac gacgagcatg taatcagccc aaaggaattt gtgcacctgg ccgggaagtc      540

caccctgaag gactggaaga gagccatccg catgaacggc atcatgctca ggaagatcat      600

ggactccggg gaactggact tctaccagca tgacaaggtc tgctccaaca cctgccgcag      660

cacaaagatt gacctctcag gagcccgtgt gtccctgagc agccccacgt cggccgagta      720

cattcccctc acgcccgccg cagccgacgt gaatgggtct cctgcgacca tcaccataga      780

gacctgtgaa gaccctggcg actggaccgc ggccattgga gatgacacat ttaccttctg      840

gcgggggctg aaggacgccg gcctgctgga cgaggtcatc caggagttcc accaggagct      900

ggtggagacc atgagaggcc tgcagcagcg ggtccaggac cctcccctgc agcttcgaga      960

tgctgtactt ctcaacaaca tcgtgcagaa cttcggcatg ctggacctgg tgaagaaggt     1020

gctggccagc cacaagtgcc agatggaccg ctcgcgggag cagtacgccc gggacctggc     1080

agccctggag cagcagtgtg atgagcatcg tcgccgagcc aaggagctga agcacaagtc     1140

ccagcacctc agcaacgtgc tcatgacgct gacgccggtc tccctgccac cgcctgtgaa     1200

gcggccccgg cttgcacgtg ccacatcagg accggccgcc atggcctcgc aggtgctcac     1260

ccagtctgcc cagctggcgc ttggcccggg cgtgcccgtc ccccagctga ccagcgtgcc     1320

ccttggtaaa gtggtgtcca ccctgccgtc caccgtcctg ggcaagggtt cccttcaggc     1380

gccccccgcc agctccccgg cctccccgct gctcggggga tacacagtct tggcctcttc     1440

cggctccacc taccccagca cagtggagat ccacccggac gcgtccagcc tcacggtcct     1500

gagcacggcc gccgtgcagg acggtagcac ggtgttcaag gtggtcagcc cgctacagct     1560

gctcacgttg cctggcctgg gccccaccct gcagaacgtg gcccaggcct cgcctggctc     1620

cagcacaatt gtgacagtgc ccgcaggggc tgcccccggg cctgaggagc acacggccac     1680

cattgaggtg gctgccatgg cagaggacca cgagcggaag tagccgacag gagggcgagg     1740

cccctgggac ggacagggct ggctgtctct cagccgcggc agcagggagc gggcagaggc     1800

cgcagggctg gctcgggcag gtgggtcacg tggtctgcag aaccaaagag aggaatcgcc     1860

aaaacaaatc acgagaagag agaaggggac agaacagcga gagcaacctg gaaaatcggt     1920

cttcaggtcc cacgtttcct cccccttttt tcttgggaaa tatatttttc catctgttgc     1980

ttattaatac tgtttacaca ttgggccttg atcaggagcc aggtgggcgg gggctagggg     2040

gagcctgggt gcagcagaga cagaggaagc agagccaggt gccgagcgcg accctgcagg     2100

tgctggacgc ggtgcagcag gtcacgaggc ccccatgtct gcacccagcc aggtccctgg     2160

ggacgttact aactcatgac ttgggagcta agcccaagtg tgaaacctct ggatcctatg     2220

gatttggttt cttcccacag ttttctgtag gtttagtgtg gctggcgccc cgttctcctc     2280

cagttgggaa catgcacccg gagcttgggg tgcagatcct gatgggtgcc tgcctccccc     2340

gcccccagcc ggtgctcagg tggcccaggg gccgcacaga cgaggcgtgg tccaggcatt     2400

gttgcacatg tactgagggt gtttttaagt gaattgctta gtaggcttct aggaagagtc     2460

agatttatag cattttcaac caaaataatg gtgagtgcct aggcttcccg agttagctct     2520

ttgggtggcc cctgagcccc tgtgagtgca cttgaccggg tgcggaggtc ctgggcagcc     2580

tgtccctgag ccggcccctc ccaggggtct gagatccatg aggtgtgtcc ctagggcttc     2640

agtcctgggg cagaggcata aacagaacca gtcactatgg aggtcgagga ttcccatgtg     2700

ggcccttcag cttgggctgc ttggccacgg aacagccctt ggctccctgg cccccggccc     2760

ccatgcagcc cctgggctgg cccttggtgg tctctgtcca agggagagcc cctgggtgtt     2820

caggaggctg ccccgggtgg gctgctcagg gcagctgccg aaggtggagc ccagagcctg     2880

tctggaaggg ctgtctgtgg ctgtcctgag acctggcctt ggactcacaa ggaagaccag     2940

gctgaggccc ctccaggcca gggtcctggg gcaggcatct cagggagcag ccagcccagg     3000

cctcctgccg tctccaacag ggcatgtccc gggaggaccc tgagtgccag attcccctgg     3060

acgctcctgc tgattctgtc ggcagttgaa ggcccgtctg aggccccgca atgcgagggt     3120

cctgtgtccc acttcactgc tccgaaggga actggctggc tgtccgtcca gtgagcggcc     3180

cagaccccac ctctgcgcca ttgtcaccag ggccctgtcc tggctgccct cacccatgtc     3240

aagctactga ggctgtgtct tgtttgtttt ctctgttaca tttttgtttg ctgttgtcac     3300

agtcagctgg tttcggcgtg atgttgatct tttgatgtac atactccgtt ttaaactcat     3360

ttccactcta gttgagttct gcagcatgca gcggtatgac cctacggggg tcaggagagc     3420

cctgcggccc ccacccacca gctcagaacc tgtcactaat acagctgcct gtgaccctgg     3480

gacccgcaac cttccagctg cttccctttg tcaaagtcac gagtgcgtct gccttgacag     3540

ccctcgtcaa cagaacttcc agtgggttgt gggttcattt cctttctttt taagaacagg     3600

gttgggacct tttctgcccc tgccccttag ctactgaggc atagggagag gaagttaatt     3660

tcagagccat acaaaaataa gccacaacca gcttcagaat taattcccaa tcccccattc     3720

caccagggct gggagcccat tcccagtgct tcccaaggcc ctcggggaca tctaccgcca     3780

acccagctgc ttctggcagg ggctccaagc cccagcgtgg ggaagggccc tggagaagcc     3840

ctcatcctca tgggaaccac actgcagtgg gtggggaagg ttgttgtcag caccgccccc     3900

ggctcctcca ggtcctgctg gctcctcggg ggcagggttc cctggacctc ccagttctgc     3960

gccttggggc cagccagtac tcagagagga ggaccttctc aaccacgtac agaacacggg     4020

ttttcatggc tgcctttggt ttggttttct gagaagatag gattggattg gattttgcag     4080

agggtgagaa cttctctgtg cctgctcaga ggcgccctag ggaagggcca tgtttgagtt     4140

ttgctttgta tgttgttttg caagtatctg cctggtactt tgatttaaaa taaaaacaat     4200

tttcatagtt                                                            4210


<210>  2667
<211>  3655
<212>  DNA
<213>  homo sapiens

<400>  2667
ccgagttcag tcatactgca ccagctgagc aatgcatgga gtggacctgt aggcgacttg       60

catcgtcttc aacatgaaga tagccacagt gtcagtgctt ctgcccttgg ctctttgcct      120

catacaagat gctgccagta agaatgaaga tcaggaaatg tgccatgaat ttcaggcatt      180

tatgaaaaat ggaaaactgt tctgtcccca ggataagaaa ttttttcaaa gtcttgatgg      240

aataatgttc atcaataaat gtgccacgtg caaaatgata ctggaaaaag aagcaaaatc      300

acagaagagg gccaggcatt tagcaagagc tcccaaggct actgccccaa cagagctgaa      360

ttgtgatgat tttaaaaaag gagaaagaga tggggatttt atctgtcctg attattatga      420

agctgtttgt ggcacagatg ggaaaacata tgacaacaga tgtgcactgt gtgctgagaa      480

tgcgaaaacc gggtcccaaa ttggtgtaaa aagtgaaggg gaatgtaaga gcagtaatcc      540

agagcaggat gtatgcagtg cttttcggcc ctttgttaga gatggaagac ttggatgcac      600

aagggaaaat gatcctgttc ttggtcctga tgggaagacg catggcaata agtgtgcaat      660

gtgtgctgag ctgtttttaa aagaagctga aaatgccaag cgagagggtg aaactagaat      720

tcgacgaaat gctgaaaagg atttttgcaa ggaatatgaa aaacaagtga gaaatggaag      780

gcttttttgt acacgggaga gtgatccagt ccgtggccct gacggcagga tgcatggcaa      840

caaatgtgcc ctgtgtgctg aaattttcaa gcagcgtttt tcagaggaaa acagtaaaac      900

agatcaaaat ttgggaaaag ctgaagaaaa aactaaagtt aaaagagaaa ttgtgaaact      960

ctgcagtcaa tatcaaaatc aggcaaagaa tggaatactt ttctgtacca gagaaaatga     1020

ccctattcgt ggtccagatg ggaaaatgca tggcaacttg tgttccatgt gtcaagccta     1080

cttccaagca gaaaatgaag aaaagaaaaa ggctgaagca cgagctagaa acaaaagaga     1140

atctggaaaa gcaacctcat atgcagagct ttgcagtgaa tatcgaaagc ttgtgaggaa     1200

cggaaaactt gcttgcacca gagagaacga tcctatccag ggcccagatg ggaaagtgca     1260

tggcaacacc tgctccatgt gtgaggtctt cttccaagca gaagaagaag aaaagaaaaa     1320

gaaggaaggt aaatcaagaa acaaaagaca atctaagagt acagcttcct ttgaggagtt     1380

gtgtagtgaa taccgcaaat ccaggaaaaa cggacggctt ttttgcacca gagagaatga     1440

ccccatccag ggcccagatg gaaaaatgca tggcaacacc tgctccatgt gtgaggcctt     1500

ctttcaacaa gaagaaagag caagagcaaa ggctaaaaga gaagctgcaa aggaaatctg     1560

cagtgaattt cgggaccaag tgaggaatgg aacacttata tgcaccaggg agcataatcc     1620

tgtccgtggc ccagatggca aaatgcatgg aaacaagtgt gccatgtgtg ccagtgtgtt     1680

caaacttgaa gaagaagaga agaaaaatga taaagaagaa aaagggaaag tcgaggctga     1740

aaaagttaag agagaagcag ttcaggagct gtgcagtgaa tatcgtcatt atgtgaggaa     1800

tggacgactc ccctgtacca gagagaatga tcctattgag ggtctagatg ggaaaatcca     1860

cggcaacacc tgctccatgt gtgaagcctt cttccagcaa gaagcaaaag aaaaagaaag     1920

agctgaaccc agagcaaaag tcaaaagaga agctgaaaag gagacatgcg atgaatttcg     1980

gagacttttg caaaatggaa aacttttctg cacaagagaa aatgatcctg tgcgtggccc     2040

agatggcaag acccatggca acaagtgtgc catgtgtaag gcagtcttcc agaaagaaaa     2100

tgaggaaaga aagaggaaag aagaggaaga tcagagaaat gctgcaggac atggttccag     2160

tggtggtgga ggaggaaaca ctcaggacga atgtgctgag tatcgggaac aaatgaaaaa     2220

tggaagactc agctgtactc gggagagtga tcctgtacgt gatgctgatg gcaaatcgta     2280

caacaatcag tgtaccatgt gtaaagcaaa attggaaaga gaagcagaga gaaaaaatga     2340

gtattctcgc tccagatcaa atgggactgg atcagaatca gggaaggata catgtgatga     2400

gtttagaagc caaatgaaaa atggaaaact catctgcact cgagaaagtg accctgtccg     2460

gggtccagat ggcaagacac atggcaataa gtgtactatg tgtaaggaaa aactggaaag     2520

ggaagcagct gaaaaaaaaa agaaagagga tgaagacagg agcaatacag gagaaaggag     2580

caatacagga gaaaggagca atgacaaaga ggatctgtgt cgtgaatttc gaagcatgca     2640

gagaaatgga aagcttatct gcaccagaga aaataaccct gttcgaggcc catatggcaa     2700

gatgcacatc aataaatgtg ctatgtgtca gagcatcttt gatcgagaag ctaatgaaag     2760

aaaaaagaaa gatgaagaga aatcaagtag caagccctca aataatgcaa aggatgagtg     2820

cagtgaattt cgaaactata taaggaacaa tgaactcatc tgccctagag agaatgaccc     2880

agtgcacggt gctgatggaa agttctatac aaacaagtgc tacatgtgca gagctgtctt     2940

tctaacagaa gctttggaaa gggcaaagct tcaagaaaag ccatcccatg ttagagcttc     3000

tcaagaggaa gacagcccag actctttcag ttctctggat tctgagatgt gcaaagacta     3060

ccgagtattg cccaggatag gttatctttg tccaaaggat ttaaagcctg tctgtggtga     3120

cgatggccaa acctacaaca atccttgcat gctctgtcat gaaaacctga tacgccaaac     3180

aaatacacac atccgcagta cagggaagtg tgaggagagc agcaccccag gaaccaccgc     3240

agccagcatg cccccgtctg acgaatgaca ggaagattgt tgaaagccat gagggaaaaa     3300

ataaacccca gttctgaatc acctaccttc accatctgta tatacaaaga attcttcgga     3360

gcttgtctta tttgctatag aaaacaatac agagcttttg ggaatggact cactgatttt     3420

cagtcttttc catctctttc ctcctagact ctgtgatctg agggtataaa gacatctcca     3480

ccaagtctga gccctcaaaa tgtcctgatt acaatgctgt ctgtccaact gcctgttcaa     3540

taaaagtaaa ctcagcagaa caccctttct gggatttctt tgtcactatc tggataatag     3600

atatttgctt ttaaagaaac tgaataaact ctacccttta aaaaaaaaaa aaaaa          3655


<210>  2668
<211>  4758
<212>  DNA
<213>  homo sapiens

<400>  2668
cccgagccga gcccgccgcg gtcacagcca cccgcgggaa gctcgtggcc gggaccccga       60

ggcgggagcg cgggctgggc cgggctgggc tacgcgcacg ggctcggccg ccgcccctgc      120

cggttgcata ccctgtcctg agggcgcggc acggagtgca tgcgggccgc tgccatgacg      180

accgccatct tggagcgcct gagcaccctg tcggtcagcg ggcagcagct gcgccgcctg      240

cccaagatcc tggaggatgg gcttcccaag atgccttgca ctgtcccaga aacggatgtg      300

ccccagctct tccgggagcc ttacatccgc accggctacc gccccacggg gcacgagtgg      360

cgctactact tcttcagcct ctttcagaaa cacaacgagg tggtcaacgt ctggacccat      420

ttactggcag ccctggccgt cctcttgcga ttctgggcct ttgccgaggc tgaggccttg      480

ccatgggcgt ctacccactc cctgcctctg ctcctcttca tcctgtcgtc aatcacttac      540

ctcacctgca gccttctggc ccacctgctg cagtccaagt cagagctctc ccactacacc      600

ttctactttg tggactatgt tggcgtgagc gtttaccaat atggcagtgc tttggctcat      660

ttcttctaca gctctgacca ggcctggtat gaccggttct ggcttttctt cttgccagca      720

gctgccttct gtggctggtt atcttgtgct ggctgttgct atgccaaata tcgttaccgg      780

aggccttatc cagtcatgag gaagatctgt caagtggtgc cagcaggtct ggcttttatc      840

ctagacatca gccctgtggc acaccgtgtg gcgctctgtc acctggctgg ctgccaggag      900

caagcagcct ggtaccacac cctccagatc ctcttcttcc tggttagcgc ttatttcttc      960

tcctgccccg tgcctgagaa gtacttcccg ggttcctgtg acatcgtggg ccatgggcat     1020

cagatcttcc atgcatttct gtccatctgt acgctctccc agctggaggc catcctcctg     1080

gactaccagg ggcggcagga gatcttcctg cagcgccatg gacccctatc tgtccacatg     1140

gcctgcctct ccttcttctt cctggctgcc tgcagtgctg ccaccgcagc ccttctgagg     1200

cacaaagtca aggccagact gaccaagaaa gattcctgag gctggcaagt ggggcaacgt     1260

gtggaggaag cccctcataa tttggagaaa acttgataca atagaagctg acttttaagg     1320

cattggcttt taaattaata catatatcca aggatatgtt atagctgcag tgtttgaaag     1380

ccaaaggatt taagagtttt gttgttgtta ataaaaggaa tactcctttt ccttttggat     1440

catagcttaa caaggcacag gaagggaagg gatcttgact aagattcatg agacattgaa     1500

ttaaggagaa tcatcttcat gcctgaaaat ttagcaaaat tccgactatg gcctccaggg     1560

gcaattccta aaagctgaat ggataataaa attggactgg aaagtaagta ggtggctggt     1620

cctcaccctg ttggaatggc tatcctacta tgctgttctt tggtaatgga ataaattgac     1680

ccaaggaccg aatttcattt ggatttcaaa ttgtccagag tggaaaagcc ttcaagatga     1740

catgatgaat tactcagttc atctgatttc tggtccctcc tttctcgaca actataatac     1800

taaccctttt ctcaggataa ctgtctacac ctggcagttt tctctgacgt gctgttcact     1860

cacatcccta ccttgcatgg taatataaag gactaggaag cagtcatact tccaggaaat     1920

gcttggattc atgtggacat tcaggaagct tattctcata taatactaat ctaaacagta     1980

ctagaaatta cagtgccaag agccaccagg aggcccagcc aataagcata gatactatat     2040

ggtatcatgg gacccatcta ttttttacca gtggactaca ggattacttg agagttatca     2100

gggctgccta acagaccagg agatctgggg gttgcaccag ggaatcgcca tatttgacca     2160

gcatgtttta aaagctcttg gtaggattag ttggttctaa ggatccctct agggacctca     2220

ttatttcaag aggaacccaa agtccagcct cctacataga tgctgcccca cgaaggaccc     2280

acaaaactaa cctagttcag ggttctcagg caggcagttc tgcttcagct tagagcagaa     2340

cccataaaat actcaagtac tgggataggc aagcatgtgt gtttactgtg gattggtccc     2400

tgaaggctcc tttgggtgag aacatgtgaa ccaggcaccc tggtttgttt ggagcattgc     2460

tgcccagaag cttctatggg ataggtggtg cttgggattg atgtgttgtg gccatgcagc     2520

cctccctgag gattgacttc tgcactaatc cagtgaagga ggctgtgtca aaagaagggc     2580

tcagaagccc tcttttcaga ggcaatgatt cctgtcagta tgaggtccct tagttactaa     2640

aaagggacat gatttaactc cagtttgatg aacctcctcc gagtttactt tattgtcttc     2700

aaatcttttg ttttcttcct ttttgtgaga tttgtgggtt ttgtgcctta taaatggaaa     2760

tgtatgaaca caatatatgc tcatgtagaa ttttctgttc tgggttattg ggataagaaa     2820

aaatatatat tgctcttcaa ctagtgaatg aaagaaactt cagaaagcta gaattgctta     2880

tcaatcaaaa gactttctca atctattttg gccacaaaca aacatattca actgaagctt     2940

tccaataatc tttatatcaa gaaagcatgc gtcttgtcag ctacattgtt ttcttagatg     3000

gatttctcct gttaatcctc aaatatctga acttctgtgt tacccaagtg tcttatacaa     3060

gcttctggtg tctaggacaa atttatggca aataaaatta gcaaaactga actgggttga     3120

actgaacaag aggatggggg aattgtgcaa atacgttgtt agtagaaggt caatttaaaa     3180

tagggactag aaattatttg aagttttctt tattacggat tcaaagactt attttgaaag     3240

ttggaaggag aagggaggga agagagcaga agggaagaag gtgtaagtca agctcttgaa     3300

tataactggt ggtattgtgg gcagagatct ttagttcaaa tccacgtatt ttttaaaaga     3360

gagaaccgga ggtagagcaa tgatcagatg ggtgcacaga ccagtgccaa tctgaacatt     3420

gttaatggcc tgtgacatga tgagcacagg aacaggcatg aagatattgc catacaattt     3480

taatttatac aagtattggc ccctcaagtg gttggaaatt ttttttttaa tctctttttc     3540

tgagacaggg tcttactctg tcgcccaggc tggagtgcag tgatgcaatc acggctcact     3600

gcagcctcga cctccccagc tcaagcaatc ctcccacctc agcctcctaa gtacctggta     3660

ctacaggcgc gtgccaccac acctggctaa tttttgcatt ttttgtagag acagggtttt     3720

gccacgttgc ttaggctggt cttgaactcc tgaactcaag tgatccgccc acctcagcct     3780

cccaaagtgt tgggattaca gacattagcc atcacgcctg ccctagaaac agttttttaa     3840

taggagatat ttgagaggca ttgaggtagg agactctatg acatgccctc agaatatcag     3900

aatcttctta gaaataaact aggaaatgca gatgttttta actactcaga cttttgagga     3960

attaatcctt ttaaaacatt tttgttaaag ttagtgtatc agtaagaaac agacctagtt     4020

taaaaggaat aatcaacaat tttataaagg agatggctta ttcaaccata gcccctccaa     4080

catatctact ggaaattctg ctggttaact ttatctctct ctctcttaat ttagactttc     4140

aacctatgaa aatgtaaata cctttgaaaa aactaaacta tcagtcattt acatcctctc     4200

atgaatgaaa tgcagtgtag ggagaggaga tggcaggaca cagcaaacag gacacatttg     4260

cctgcttctc tcttgcctaa ttcttcctga cctgtattta ctgatgctta ataatacttg     4320

taagactcta ggggttcatt tcccatttca gcggaaagta cttcactcaa caacaatatt     4380

ctcaagagtc ttctactgga agctagaaag aaataggaat ttaagtccat agaatgaagg     4440

tagttattcc tgcctgtgtt gcccacctgt tcacaaaaag tacctttatg cttgaaaaca     4500

ttaggttctt tggttactgc actgtagttt caaatggatc ctccagatgg cattcatgtc     4560

ttactcagaa agggcactgc cattgtcccc aaggcttctg tctactaatt ctattggtct     4620

tgtgttttgc ttgcttggca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa atggagctat     4680

tttctgtcta tataaatcta cttatatgaa taaccattaa agtgattttg tatatgcaaa     4740

aaaaaaaaaa aaaaaaaa                                                   4758


<210>  2669
<211>  6131
<212>  DNA
<213>  homo sapiens

<400>  2669
ctccgactct cggcacctgg cctccagctt tcggaactat ggaggccgcg cccgggaccc       60

ccccgccgcc gccatcagag tcgccgccgc cgccatcgcc gccgccgcca tcaacgcctt      120

cgcctcctcc gtgttccccc gacgcccgcc cggccacccc gcacctcctc caccaccgcc      180

tcccgctccc tgacgacagg gaagatggag agttggaaga aggtgaattg gaagatgatg      240

gggcagagga gacccaggat acctccggag ggcctgagag aagccggaaa gaaaaggggg      300

agaagcatca cagtgattcg gatgaggaga agtcccacag gagactgaag cggaaacgga      360

agaaagagcg ggagaaagag aaaaggaggt cgaagaagag gaggaaatcc aagcacaaac      420

gccatgcttc ttctagcgat gacttctctg acttctcaga tgactcggat ttcagcccca      480

gtgagaaagg tcaccgcaag tacagagagt acagcccccc atatgcgccg tcccaccagc      540

agtacccccc atcgcatgcc acgcccctgc ccaagaaggc atactccaag atggacagca      600

agagttatgg catgtacgag gactacgaga atgagcagta tggggaatat gagggcgacg      660

aggaggagga catgggcaag gaggactatg acgacttcac caaagagctg aaccagtacc      720

ggcgtgccaa ggagggcagc agccgcggcc gaggcagccg aggccggggc cggggctaca      780

ggggccgagg aagccgtgga ggatcgcgag gccgcggcat gggcaggggc agccgaggca      840

ggggcagagg ctctatggga ggagaccacc cggaggatga agaggatttc tacgaggaag      900

agatggacta tggagagagt gaggagccaa tgggagacga cgactatgac gagtactcca      960

aggagctgaa ccagtaccgc cgctccaagg acagccgagg ccgagggcta agtcgaggcc     1020

gtggcagggg ctcccgaggt cgagggaaag gaatgggtcg gggccgaggc cgaggtggca     1080

gccgaggagg gatgaacaag ggcggaatga acgatgacga agacttctat gacgaggaca     1140

tgggcgacgg tggtggtgga agctaccgga gtcgtgacca tgacaagccc caccagcagt     1200

cggacaagaa aggcaaagtc atttgcaagt acttcgtgga agggcgctgc acctggggag     1260

accactgtaa ttttagccat gacatcgaac tcccaaagaa gcgagaactg tgcaagtttt     1320

acatcactgg attttgcgcc agagctgaga actgccctta tatgcacggt gatttcccgt     1380

gtaagctgta ccacaccact gggaactgca tcaatggtga cgactgcatg ttttcccacg     1440

accctctgac cgaagagacg agggagctct tggataagat gttggccgat gatgcagaag     1500

caggtgccga ggatgagaag gaggtggagg aactgaagaa gcagggcatc aaccccctgc     1560

ccaaaccgcc ccctggtgtg ggcctcctgc ccacccctcc tcggccccct ggcccgcagg     1620

ctccaacctc tcccaacggc aggcccatgc agggtggccc cccgcccccg ccccctcccc     1680

ctcccccacc gcccgggccc cctcagatgc ccatgccggt gcatgagcca ctgtccccgc     1740

agcagctgca gcagcaggac atgtacaaca agaagatccc ctccttgttt gagatcgtgg     1800

tgcggcccac gggacagctg gctgagaagc tgggtgtgag gttccctgga cccggtggac     1860

ccccagggcc aatgggccct gggcccaaca tgggaccccc agggccaatg ggcggtccaa     1920

tgcatcctga catgcacccc gacatgcacc cggacatgca ccctgacatg cacgcagaca     1980

tgcacgcaga catgccgatg ggccctggca tgaatcctgg cccacccatg ggccctggcg     2040

gccctccaat gatgccctac ggccctggag actccccaca ttctggaatg atgcccccta     2100

tcccgccagc ccagaacttc tatgaaaact tctaccagca gcaggagggc atggagatgg     2160

agcccggact cctgggggat gcagaggact acgggcacta cgaagagctg ccaggggagc     2220

ctggggagca cctcttccct gagcaccctc tggagcccga cagcttctct gagggagggc     2280

ccccaggccg gccgaagcca ggcgccggtg tccctgactt cctgccctca gcccagaggg     2340

ccctgtacct gaggatccag cagaagcagc aggaggagga ggagagagcg aggaggctgg     2400

ctgagagcag caagcaggac cgggagaatg aggaaggtga caccggaaac tggtactcaa     2460

gtgatgagga tgagggtgga agcagtgtca cctccatcct gaagaccttg aggcagcaga     2520

cgtccagccg acccccggct tcagttgggg agctgagcag cagtgggctg ggggaccccc     2580

gcctccagaa gggacacccc acaggaagcc ggctggctga ccctcgcctc agccgggacc     2640

ccagactcac ccgccatgtg gaggcttctg gcgggtctgg cccaggtgat tcgggaccct     2700

ccgatcctcg gctggctcgc gccctgccca cctccaagcc cgaaggcagc cttcattcca     2760

gccctgtggg ccccagcagt tccaaggggt ctgggccgcc cccaacggag gaggaggaag     2820

gggagcgggc cctgcgggag aaggccgtga acattcccct ggacccactc cccgggcacc     2880

ctctgcggga cccacggtca cagctgcagc agttcagcca catcaagaag gacgtgaccc     2940

tgagcaagcc cagcttcgcc cgcaccgtgc tctggaatcc cgaggacctg atccccctac     3000

ccatccccaa gcaggacgca gtgccccccg tgcccgcggc cctgcaatcc atgcccaccc     3060

tggacccccg gctgcaccgc gctgccacgg cagggccccc caacgcccgg cagcgcccgg     3120

gcgcctccac ggattccagc acacagggcg ccaacctccc cgactttgaa cttctgtctc     3180

gcatcctcaa gacagtcaat gccaccggct cctcggccgc ccccggttcc agcgacaaac     3240

ccagtgaccc ccgggtgcgg aaggccccca ccgaccctcg gctgcagaaa cccacagact     3300

ctacggcctc ctcccgggct gccaagcccg gccctgctga ggcgccctct cccaccgcca     3360

gcccgagtgg ggatgcctcc ccaccagcca ccgctcccta cgacccccgc gtgctggcgg     3420

ccggtggact gggccagggc ggagggggcg ggcagagcag tgtgctgagc ggtatcagcc     3480

tctacgaccc gaggactccc aacgcggggg gcaaagccac agagccggct gctgacacgg     3540

gtgcccagcc caagggtgct gagggcaatg gcaagagctc ggcctccaag gctaaggagc     3600

ccccgttcgt ccgcaagtct gccctggaac agccagagac agggaaggcc ggtgctgatg     3660

ggggcacccc cacggacaga tacaacagct acaaccggcc ccggcccaag gctgctgcag     3720

cccccgctgc caccaccgcc accccacccc ccgagggtgc cccaccccag cccggggtgc     3780

acaacctgcc cgtgcccacc ctcttcggga cggtgaagca gacacccaag acgggctcag     3840

gaagcccatt tgctgggaac agtccggccc gcgagggtga gcaggatgcg gcatccctga     3900

aggatgtttt taaaggcttc gaccccacgg cctccccctt ttgccagtag tgtccagcca     3960

gagctgcggc tccagccacc cttcctaggg tggcattcag ggcagcaccc agggtaggga     4020

acttgggggc aaggggaggc aggctgggtg ttcctttttt cttttctttt tcttttgctt     4080

tccgtctctt ttattttttt ttaaagtagt actttctttg agatttgtaa attgtatata     4140

accatcttaa gttctggtca gtgtggcggg ctcaggggct cctgctgagc aaaccgactc     4200

atgcccgcaa acctgtgaac tttcgccagt gcctggcctc agactctgtg ggctctgcgt     4260

ggccgggcct tgctggaggc ccagtgggtt ttctgggcaa agcatggccc cttttcccca     4320

ggacaaaggg aacagttggt gtctgggaag gtattgaacg ctcctcaccc tgtgcccgaa     4380

gagacccgga accaagacca tggcagggcc tgcgtggaag caggtccagg cgtttctaga     4440

accctagggt gcaccatcac tgtcttttca gtgcaggctg taacaaccca ctcaggagac     4500

agtgagagtg aaaaggtatt aaggaaaaag cccccagcgg cactatgggg gctccctggc     4560

gcatgcctgc tcctgtccct ggattaccac acgtgccctc cctgccaccc tccgtctaga     4620

gcaagcggat gccccccagc ctgcagcaga agcctccaca gtgagaactg gacccaaagg     4680

tagtgggggc cggtgtgggg cagagtcctg aagagccacc tctaggaggc agcccctagg     4740

agcacgcacg ttctgtcagt attaccccac ctgtcctatc aggtgggcca caccctgctt     4800

gcccacacca gggtctgtcc tggtcctcaa gccacgcacc cgctatgcct gcactgcagc     4860

ccagccccgg acagctccag gatccgtgca gtggctgcgc cgccaggccc caacaatggg     4920

gaccctgggg tggctcctgg ccaagtgttc tctgttttcc tcgcacctcc ttacactgtg     4980

tgacctgcag ggcatgaggt attgatgtgt tcgggtttcc tttcccaagc cagcagatgc     5040

aggtgttcca aggtgtgttg ctctgtggga tttgtggaca cttaagaaac ggactgagtg     5100

ggaaccctgc agccagggga tggggagcct ctgctccccc catgctccca ccctggctga     5160

gggccagcct catctgcaga gccctggagg aggcccacct atggacacag cccgagagat     5220

gggcgcaagg ggtgctgggg gaggcctgct atcctgcctc tgggccactt gaggggcctc     5280

aggaagtgtg tgcttgtggc tgcatctgcc cgtctccctg gcccaccatg tggctgcagg     5340

ccaagctctt cattgctgac catgaagaga cctagttacc tgccaaggga ttccccttcc     5400

ctcctcctca gggtggggtg aacaaggctc ctatcccacc ccaccccaaa aagagaaaaa     5460

tgaaaaactc atagtttgga gccaggaggc agggtgtcct acagggctgc acagccctga     5520

ggggtcagtg ctgggatctg gttggttggt ttgtcttttt gtcttttttt tttttttttt     5580

ttttacacaa tcattaatga gatttgtctt cagccaccag tgttggcctt gaagcagagg     5640

gcacagccct tggtgtttgt aaaataagta tgaatacaca gtgtggcagt gttgtggttt     5700

ttgttgttgt ttttcctctc cttttgagaa ttttcttttg taaaagaaaa atatttttta     5760

aaccgaaatc tgtggatgaa atagaagctg gagccctcct cttggaatat tcagcctaag     5820

aacctcatag gactatgaat tcacccgaaa ttctcatttg ccatcaggcc gagcttttaa     5880

agaaaaattg ttctctaacc aggattgtaa caaaagtgta aatactgttt cagagttgag     5940

agttggtggt gcaaatatgt atataatgaa ctgtattttt acaatgatcg ccgcatgact     6000

atttcacacc ctttttatac tccatatctg tcttccagaa acgtcacctg cctttctcct     6060

gtggtctctt aatccagtaa ttgtattact gccattaaag gatgcagtta ttttaaaaaa     6120

aaaaaaaaaa a                                                          6131


<210>  2670
<211>  8554
<212>  DNA
<213>  homo sapiens

<400>  2670
aacatttaca acaaagttga ttctgtgtag ggttggaggc tagacagttc cacaaatttt       60

tagtcacatt ttccatgtca gttaaatcta gggagttcaa gactactgga aaaattagtc      120

tcattactaa aagaaactta gagaacgagg gaggtaccag agtctaggag gtacctctgg      180

gttgcagaag taattgtaaa ataccagacc tgttcttttt actaaaagct agtttcacta      240

tcttctggtc tgaaatactg aggcaaatac tcaagactta ttttcttcct aatcttgctg      300

gtgaaacaga agttactaga aagaaaggaa gaaaaaactt gatttggtga ctgcaggaag      360

caacacgttg ctgcttttat tctacagata atgatttatg aggaatccaa gatgaatttg      420

gagcaggaga ggccgtttgt ctgcagtgcc ccaggctgct cccagcgctt cccaacagag      480

gaccatctga tgattcatag gcacaaacat gaaatgactt tgaagtttcc ttcaataaaa      540

acagacaata tgttatcaga tcaaactccg accccaacga gattcctgaa gaactgcgag      600

gaggtgggcc tcttcagcga gctggactgc tccctggagc acgagttcag gaaggctcag      660

gaagaggaga gcagcaagcg gaatatctcg atgcataatg cagttggtgg ggccatgacg      720

gggcccggaa ctcaccagct tagcagcgct cggctgccca accatgacac caacgttgtg      780

attcagcaag ccatgccgtc gcctcagtcc agctctgtca tcactcaggc accttccacc      840

aaccgccaga tcgggcctgt cccaggctct ctatcttctc tgctacatct ccacaacaga      900

cagagacagc ccatgccagc ctccatgcct gggaccctgc ccaaccctac aatgccagga      960

tcttccgccg tcttgatgcc aatggagcga caaatgtcag tgaactccag catcatgggg     1020

atgcaaggtc caaatctcag caacccctgt gcttctcccc aggtccagcc aatgcattca     1080

gaagccaaaa tgaggttgaa ggctgcattg actcaccacc ctgctgccat gtcaaatggg     1140

aacatgaaca ccatgggaca catgatggag atgatgggct cccggcagga ccagacgcca     1200

caccatcaca tgcactcgca cccgcatcag caccagacac tgccacccca tcacccttac     1260

ccacaccagc accagcaccc agcacaccat cctcaccctc aaccccatca ccagcagaac     1320

catccacatc accactccca ttcccacctt catgcacacc cagcacatca ccagacctcg     1380

ccacatccgc ccctgcacac cggcaaccaa gcacaggttt caccagcaac acaacagatg     1440

cagccaaccc agacaataca gccaccccag cccacagggg ggcgccggcg aagggtggta     1500

gacgaggatc cggacgagag gcggcggaaa tttctggaac ggaaccgggc agctgccacc     1560

cgctgcagac agaagaggaa ggtctgggtg atgtcattgg aaaagaaagc agaagaactc     1620

acccagacaa acatgcagct tcagaatgaa gtgtctatgt tgaaaaatga ggtggcccag     1680

ctgaaacagt tgttgttaac acataaagac tgcccaataa cagccatgca gaaagaatca     1740

caaggatatc taagtccaga gagtagccct cctgctagtc ctgtcccagc ttgctcccag     1800

caacaagtca tccagcataa taccatcact acttcctcat cggtcagcga ggtggtagga     1860

agctccaccc tcagccagct caccactcac agaacagacc tgaatccgat tctttaaaat     1920

gcaccatcag acctggcctc caagaagagc tgtagcgtac catgcgtcct ttcttttaag     1980

ggcattttta gaattaactc agacctggaa gactcctcag ttcttcaaag actggctttc     2040

atttttatag ttattatgga aatgttgtct tttatactta gttatataag aaaaaaggga     2100

gttatgcaat taatatctat cagcttggga aacgctttgg tgcttttctc cagttttctg     2160

gtaccagtta cttgtttata aactgaacct tttctgtata tagccatggt ttcattctta     2220

tcagtccaac cctttgcctg aaacattgaa tcttgttaaa ccacagcttt tagctaaaat     2280

gaggtatacc tagatgtcaa gtaagacaga tccaaggtaa ctgggtagga aatcttttga     2340

catcttaact catgttgagt ttgtgctgtg gtgtcaccag aattccagat aaacacacag     2400

cctttcccat accttttttt ttcttactat aaaatattat aagatccatt gatgtccaaa     2460

taataccacc aagcatctct tcacctctcc tcctcttggt ccacttgcta atgcccagtt     2520

ttcttctcca tttccacttt ttcttaggct ccctatttac tattcatttt gacttccttc     2580

tgttttattt ttttcccttt agcattgcat gtgaataaga aaataatgtt taaagaaaaa     2640

aaaaaaaaag caaacctcca aaacgtggac ctaaccattg cttcacttac acttcaccca     2700

cagctggagt tcattcaact cttgcttttc acaaaatagt aaccaggaga tgtttaatgt     2760

gcctgattta atgtttttaa taatcacagc aaatgaaagg tggtttagtt ataagtgaag     2820

catggttgaa taccagctgg ggagacacta gggaagggag ctttgtaagc cttgattgcg     2880

aaagtccaaa ttttgatgtg gggctataac atgacaccct tggattgcga ctggttttat     2940

acggcctgcc tataacgttg aaaatccatg tactacataa taattcagaa gggctctatt     3000

cactacacag attacattgt tcaatcatca gctgctaata gcctaagatt tatttttttt     3060

tttttcttaa gcctatggaa ccggctttgc tgttctgggg ggtgaaaata gactaactac     3120

tggagaaaca aagagagaaa gaaaacccag tgtttccata ggggcacttt tagccttccc     3180

acaacagtta agcactcttt gactgctgaa ggaaccccat ggatgaggtg caggctactt     3240

cactcttttt ttttcttttt tgagacagag tctcacctat tgcccagact gaagtgcagt     3300

ggtgcgatca tggatcactg cagcagcatc ctccgagttc aagctatcct tccacctccg     3360

cctcctgagt agctgggacc acaggttcac ataaccatgc ctggctaatt tatttttact     3420

tttattttaa aataaaagat gaggtctgtc ttatgttgcc caggctggtc tcaaactatc     3480

ctacttcttc ctcccaaagt gttgggatta taggtgtgag ccactgcacc cagcctactt     3540

cactcttctg aattattctg atttattttc aacaactttt gtgaacttgc ccgtgataca     3600

aagcagatag tccctgaacc acagtcgtgc ctccttgaaa caagccattc tactgtgcta     3660

atgttttaat atcacatctc acaaataaca ggggtgaatg tttctctcta gcaatctagg     3720

caggtgctgg tgtttcatct ccatttgaat gcttgacctc ttaatgtgtg tgtgtgtgtg     3780

tgtgtgtgtg tgtgtgttca tgggttttaa aagaacagta ttttacaaaa ggtgtagctt     3840

ttataagagt gcagaaaagg gaaggatgtg tttttttctc tcactatagt ataagaatct     3900

attttggaga aaaaaagaaa atatgagggt ctcgaagcat gatttttata taactagttt     3960

cagttttatc taataactta ctttttaaat caatatttat caacaatctt tccttgtatg     4020

cagtgctttc aaaagatggt tttgagtgtc cagtgaaact tatgacttgg atatatggtt     4080

gaagaatcaa aacaaaagca aaaaaaaaaa gcaaaaaaag aaaagagaaa aaaagaaaaa     4140

atgcaaatgg aataattttc tattatattt tagacaaaca tatcattttc gagtatttta     4200

aatactgaat tcatagttgt tgttttttaa attccaacag taacagctga atggtttaat     4260

ctgactggct tcctaagaaa tgtttaagac tcagctttaa aaagaagtta acattcatat     4320

ctctgttttg aaatcaaaaa tcatatttca aaattctttc ctaggaccat ctatgtgtct     4380

cccctcccct ccacaaaaag gagaaagagt gcattaaaat gtttagttgg gttttttaat     4440

ttttaatttt tatgttatgt tttgctttgt tttaagtaaa caaaaatttt tctttcttta     4500

ctgcatgcat agcacttaat aaaatggatt tttaaaaaat ccactagtaa tatcagaatg     4560

tccagggagt gactgtcact acaatgatgg tttagtttac ttctgttcca ccttttgatt     4620

gaaatattta gttgttaggc tgaaagcctc ggcagttaag aacttgcctg agttttcttc     4680

gttcagcaac ttgacagttt gactgatgtg cattatatat agctcaatta tgtctgtttt     4740

ttatgctaag taggaaaacc aaccacacac attagcaaac cggcctcaac atataattag     4800

aataaactgt cttcttgttc tactcagggc ctttaggtgt gttcattcac ggtatggaaa     4860

tacagtaaat gaaagattcc aactagttgt cagtgcttct tgaaattcca aacagaaaga     4920

tacattggtc aaatccaaca cttggcttat caatattaag tcttttacct aaaggcccag     4980

ccgtcaccag acaacagaat aatcaatctg cctgaaaatc cctcctcctt gtcctacact     5040

ttttgcctgt ttgggagaat atctttgtac tccattctcc tccctcagcc agttactggg     5100

tcacccatcc atgtgttcat gaatcaatca tcacggcctg cagagcacct gtcctaagga     5160

gggaaaatcc tgtcacactg cctctcccca ttcgtgtgtg gttttcttga tcggtgagat     5220

ctgtctctga agtcactgcc agcctccctg ggaacgtcta tagtgcctcc cctgccttat     5280

gtgatgggag ttaacaactc agataagtac acctgagagc atttctatca ggtaaactgt     5340

cacttaaatg gaggtgtcca catcttaatt gtttctcctt gacacatttc tcaatccacg     5400

aagccaggag aggtagagtg aaaatcccag ccatggatga atgtactaat ttgaaagcca     5460

agtgttaagt cggatgtttt cccgttacac tactactcag ccctctcctg cggccacatc     5520

aacggatgca agtcacagtc ttaacacagc ctgtgggaga caagcagttt gtgtgctcac     5580

agtatatatt atagtaatta gggtgactta gagcaaatac tcttcagatc ctatgtagtc     5640

agtgaaacaa aatggagagc gtattctgat agaaggacgt cgacggtgaa tgttctggtg     5700

gttgttgcct gttaagtaaa ctttagtgtg taagttgagt ttgtcattaa aatcataaac     5760

cagctgcggt aacagacaag cctttggctg gggagtttta agcctcggta actgctataa     5820

aactagccat ccagttagga tagaatgtgt ttctttctgg ttaaaaaaag gaaaaaccat     5880

ctaagaaaat atatatgtat gtatgtgtgt atacagtgga attcaaagga ccaaagcaaa     5940

atttgaacag gaatctatta atttagaatt ttataagata tttattaata aatgttattt     6000

ttaaacattc catttgaaca gtattctgta ggatctactt gtttttaaag tgttagtcca     6060

taataaacta ctatagttat gtgtattttc atttttcagg gtttcaaatg gctattctcc     6120

atcatttggt ggaaatgttt gcttagatct ctgtgcatag acatttcaag gatttttatt     6180

gctctgtgag ttatttttta atcaacattc tgaacagttt tttttaaaca tttatttctg     6240

tgtgttcatt tttaaagtaa gctctttcat ttaggaagca gagttcagct aaagggaatc     6300

agtaactcta actggaacag ctttcttgta gaagtgtaaa aacagcttca tctctgcctc     6360

tctccacccc accccaattt cctagaaagc cttgcactat tcagctccct tagtgctttt     6420

tgtcccttcc cgaacaatat gcagtagctt taagccattc aagctccatt atgcagtata     6480

tctgagaagg gaaaggaaac aacccattta aatttgaata aaaccgtgcc tatgcgaaca     6540

gtagcaattt agaatctctt ttctgctttt aaaataattt atatttaaaa attgcacttt     6600

agctttttga tccctttgta tttctcttat tctctttcta acctcttctc tgtcctcaaa     6660

cttgcctttg ctctccttta caataccccc cacccctcct ccaaggctct gagcggcatc     6720

atttaaaata ctttacagat atttgcacca ggtacattta tgtgcgtcca ttggtagcac     6780

agctgagacc tgtgtctcac atcagcctag gtgaagccta ctacaagaat gccaaggaga     6840

agagccagta cactatatgg tttatactct ttatcccttt attcatagca tgttttttaa     6900

aaatgttata ttatgcaaca gatgtgaggc agcagctaag ctatacttaa gaattttctc     6960

tcaccttcca aaccaaagtg tcctgaataa gccaggagac ttattctttt gtgcaccctg     7020

gtgcacatct gactgttgtc ctagccatag actctctgag gccactgaaa gaacagtggc     7080

cctatcgatt tcattcctag gtctcaaaaa tacaatgttg ccttgtaaca taattaggga     7140

cagcacctct atttcacaat tataatctaa ggtaggataa gacgacacag cagcaataaa     7200

cttacaagta aaattcaata ccaaaacaaa cacaaagaaa tttaaaaaac aaaaaaccta     7260

gctcatcatg ttgtgaaaat gaaaaagtga atgtccattc aaaatatttt actatttctt     7320

gtggagtttt tcagtgatgt aatgcttgta gccaaattgc ttaaagagtg tttatatatt     7380

tttttcctta taaattgtct attttttaaa aaagctattt aaccacagct gaagtggggg     7440

gtaaggccaa attgccaaca cttgttaaaa gattaatact cttaagtggc actctgatac     7500

ctttccaact tgtcatcaga aaggaatcaa taattaccaa ctgttgtatt tagaccaact     7560

tacaatatct agctcattag aagccaggat ctagaaagct ccttctaagc catttaagat     7620

attcttacat tgagcttcat attatagaac tttataggat tggatatttt acaatagaat     7680

aatttagcct caggactgag aatgtggaag ctgaataaat tagctttaaa tacatcatta     7740

aaatcttatg cacaataagc tcattagatt ctagttttct cctttagaat accaatgcca     7800

cagacactac aggagataat gaaaggtatc agttgtgttg agtggaggga gtttaagaga     7860

aaggaccctt cccaaccagc agccagtaga aaatacaacc tactcacctt tttcccttct     7920

aagttctgct aaatcacatc tgcctcatag agaaaggaat gttgcctttg agaactgtct     7980

tggagaacag ataagcttga aatgttctct ctagagagga catagggttt gggatcctct     8040

gaaaaggccc agaaaaatag ctcagttcaa atacaatgtt ctaggacaat tggaatataa     8100

atattgtcca aaaatataat taaaagaaaa aagtttagca ctgtgtaaag taagtgttaa     8160

ctgaggaagt cccaaaaagg tgctgtcact ttaagttctg gacttggggt tctttgtatt     8220

tgtaaacagc aaagcatttg tgtttgtttg tctatttgta aagcaaccac cttccttatt     8280

ggaaggagaa aaaaaggggt acatacatgt aaatacttgc tgcagcattt aatatgttta     8340

attttgtgtt aagctttttg ttgcatcgtg aacacattta ttgttaccaa tggacaatga     8400

gttcattaag actgttcaac taggtcagat ttttacatct ctttctagca agaagagaca     8460

agattttgtg catttgtaca aatgttaata tcactgcaat tccaatataa taaagcactc     8520

aaatgcaaat aaaaaaaaaa aaaaaaaaaa aaaa                                 8554


<210>  2671
<211>  2556
<212>  DNA
<213>  homo sapiens

<400>  2671
gcggccgcct ccccctcccc ctccccctct ttcttctcct ccctcgtcgc cgccgccgcc       60

gccgccgcct cagccttcgc ctcagccgcc gcccgctccc gcccgcgcgc ggcgggatgg      120

acgatcaatc caggatgctg cagactctgg ccggggtgaa cctggctggc cactcggtgc      180

aggggggcat ggccctgccg cctcccccgc acggccacga aggggcggac ggcgacggca      240

ggaagcagga catcggcgac atcctccacc agatcatgac catcaccgac cagagcttgg      300

acgaggcgca agcaaagaaa catgccctga actgtcacag aatgaaacca gcgctcttca      360

gcgtcctgtg tgagatcaaa gagaaaacag gcatgtaatg aatttactac acatgtgatg      420

aaccttctcc gagaacagag tagaacacgt cccatttctc caaaagagat tgaaagaatg      480

gtgggcatca tccatcgaaa atttagttcc attcagatgc agctcaaaca aagcacttgt      540

gaagcagtta tgattttaag atcaaggttc cttgatgcca gacggaaaag gcgtaacttc      600

agtaaacagg ccacagaaat cttgaatgaa tatttttact cacacctcag caacccctac      660

cccagtgaag aagccaaaga ggagctggcc aagaaatgca gcatcacagt gtcacaggta      720

tccaattggt ttggcaacaa acgaatcagg tacaagaaga acattggcaa gtttcaggaa      780

gaagccaacc tctatgctgc aaagacggcc gtgacagctg cacacgcagt agcagcagct      840

gtgcagaaca accagaccaa ttcgcccacc acaccaaatt ccggtggata ccctccgtca      900

tgttatcaat cagacgggag gctacagtga tggccttgga ggaaattcac tgtacagtcc      960

acataattta aatgctaatg gaggctggca ggacgcaaca actccatctt ctgtgacttc     1020

tcctacagaa ggcccaggaa gtgtgcactc ggatacctct aactaatctc tggccacact     1080

tttccctgag ctacatgcct tgataagtgc attcagagca ataggaggaa aaggaaagcg     1140

tttttgtagc ccaccatcta cagctttact gtaaaacctt gtcttattcg agaacttggt     1200

aaatctgttt tttaaggaat cataatcatt tgtatttata cttaaaaaca cacaatgtta     1260

aaaaaaataa agcactttat ccaattaggc caagatttaa cattgttgac agtcctgtag     1320

ctattttatc ataatttatt atcaatattt tacattaatg gtttcacagt tgccaattac     1380

ttggccttaa gggtaaaaag tacaatatac actaaacctc aaccgttaaa gcagatgcaa     1440

aaattcacct cacctaaatt gaacttcttg catatttcca ttactgactt ggattgtctt     1500

tctttcatat cactaatgga gttggaataa agagctgttt gcctatccct gttaatgatg     1560

gttgtgttta agaatcttcc tcgtcacgtt tgtgttcaga tctcttatgt tataattaga     1620

tcagagactg gtagcatcgt ttctctctct gaaagcacca gtgcccagag tctgctcggt     1680

aataaaatta tggatccaga ttgttctgag agacgaagat acttgctgct gatagaggtg     1740

aaaacgagat tgatccgtct ggggttttac ggtgtgcact gggtgctgca cagacttgtc     1800

aaggtttgct acgtcctctg ggcatctgca aaaggccctg ctctctggag tgttgtatat     1860

agtgtagcaa aagagtattt atacatccca ccaatcaaaa cacagcttta ttacctcatg     1920

cgaactcata caaaccaata gaatttcaac atgttctgta gcttagagtg ctcacttact     1980

acctctgaac aatactcacg ctgtagtttg tctctttctt atctttttgc atcttgtaat     2040

taactctttg tttcccttca taaaatgtaa tgtacattgt aatcttttaa aagaaaaatc     2100

agggttgcac ttgcaacttt taaaaaaccg agtgtggaaa cattgggtct taattcaaca     2160

caggatcggt aaaactgttg taaatactga gaaacatttt gaatgttctt catcttatta     2220

ctaatccatg caaaaaaaaa aaaaaaagca gcgactaatt gtgatgcatt cagatttcag     2280

tattcagtac tgtatatttc accctgtgta atggggcccc ctctcctttc tctctttttg     2340

tattgtatgc gattctgaaa ctgattgagt catgaaaata atttgtggcg gtgattctaa     2400

tgtattaaaa acgtttcgtg ttcctttcta actggattac accctggatt gaaaaagtct     2460

tcctcgtggt agttatatgt agtttcaaac atgaataaac tttttgcttt catgattaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                               2556


<210>  2672
<211>  3939
<212>  DNA
<213>  homo sapiens

<400>  2672
gcggcgagta acgagcctgc ctactgcccg ctgcccgcct gcccggccgc tagccggctc       60

cgccacttgg cgcagcccag cccggaggcc ggtacccagg gagcctcctg gccccgcggt      120

tctgtgcact cggggagagg aggggtgccc gggacaggat tggcaaactc cgccctccac      180

ttactatttt gcttattttt ctttgtgcgc gcctgttagt ttgttaaacc agatctagtc      240

cgagtctttt ctcctccctt ctcctccctc ctcctccccc cgccaacacc ccctccctgc      300

tctttcttcc cctcctccct cctatccctc tgcaggagac tcttgcagtg acggaaagtt      360

gcagcccctg gtagcgcctt gggggtctcc ccgcagtgtc caaccgccgc cacccctttc      420

cgactacggc acttcggaga tctcctcctt cgccggtacc ctctctcact tcggccggat      480

cgcctgtgcc cagaacgtcc cacccatgac gatgctcctg gacggaggcc cgcagttccc      540

tgggctggga gtgggcagct tcggcgcgcc gcgccaccac gagatgccca accgtgagcc      600

ggcaggcatg gggctgaatc ccttcgggga ctcaacccac gccgccgccg ccgccgccgc      660

cgccgctgcc ttcaagctga gccctgccgc ggcgcacgat ctatcttcag gccagagctc      720

ggctttcacg ccgcagggtt cgggctacgc caacgccctg ggccaccatc accaccacca      780

tcaccatcat caccacacca gccaggtgcc cagctacggt ggcgctgcct ctgccgcctt      840

caactcaacg cgcgagtttc tgttccgcca gcgcagctcc gggctcagtg aggcggcctc      900

gggtggcggg cagcacgggc tcttcgccgg ctcggcgagc agcctgcatg ctccagctgg      960

catccccgag ccccctagct acttgctgtt tcccgggctg catgagcagg gcgctgggca     1020

cccgtcgccc acagggcacg tggacaacaa ccaggtccac ctggggctgc gtggggagct     1080

gttcggccgt gctgacccat accgcccagt ggccagcccg cgcacggacc cctacgcggc     1140

cggcgctcag tttcctaact acagccccat gaacatgaac atgggagtga acgtggcggc     1200

ccaccacggg cccggcgcct tcttccgtta tatgcggcag cctatcaagc aggagctgtc     1260

gtgcaagtgg atcgacgagg ctcagctgag ccggcccaag aagagctgcg accggacctt     1320

cagcaccatg catgagctgg tgacacatgt caccatggag catgtggggg gcccggagca     1380

gaacaaccac gtctgctact gggaggagtg cccccgggag ggcaagtctt tcaaggcgaa     1440

gtacaaactg gtcaaccaca tccgagtgca cacgggcgag aagcccttcc catgcccctt     1500

cccgggctgc gggaagatct ttgcccgttc tgagaacctc aagatccaca agaggaccca     1560

cacaggtgag aaacctttca aatgtgaatt tgaaggctgt gacagacgct ttgccaacag     1620

cagcgaccgt aagaagcaca tgcatgtgca tacctcggac aagccctata tctgcaaagt     1680

gtgcgacaag tcctacacgc acccgagctc cctgcgcaaa cacatgaagg ttcatgaatc     1740

tcaagggtca gattcctccc ctgctgccag ttcaggctat gaatcttcca ctccacccgc     1800

tatagcttct gcaaacagta aagataccac taaaacccct tctgcagttc aaactagcac     1860

cagccacaac cctggacttc ctcctaattt taacgaatgg tacgtctgag gacaaacaca     1920

aaccctgtta attatagaat ggaccaaata catttttaaa agaaaactga gaccaatcag     1980

atggaaatgg agttttaagg caagaggcca tatatagggc tacatcttgt taattgcaat     2040

tgtccaggaa ggttttgggc aagatccaaa agtagccatg cccttttctc aggatagaaa     2100

atatgttttg gcatttgaag cattttttac aaaatcttta cactactttt tcttcccctt     2160

cctcttgctc tctgcacacc ccattcttaa actcctccaa ttcattttaa cacttgtcct     2220

gtttcttgag aggaagttat agaaggcttg ttggtggtgg tgatgttaaa ctgatggaaa     2280

ttctttttcg ccttagtggt gattgtttaa actctcacag tcttaaaccg tgccaaagtc     2340

ctgttatgtc ttgaactttt cctcaaagca ttacacttgt gaatgtattt ttgtctaata     2400

gggtcgaaac tgttgttcag tattttttca ggctgaggat gtgatgttac tctacacatt     2460

gtgacgttta gtatacagtt gccttttgta ataacttttt ttttgtaaat acatatccat     2520

tgatgccata tttatcgttt gtaatttaat tattgctaca agtgccggga actgaacaat     2580

atttatggat aaatgttttc taacaaattc tgtacagctt ttgattataa ctgctttagc     2640

attaaaaatt gttttgaaag aagaacacaa tttacaattt tggaaccact gactcctttc     2700

tcttgttttg taacagcctt cttctacaaa gaggagatgt gagcaaatta aatcttgttt     2760

gttggtattt ataactcact cagatccctt ttttaattgt taaattattt ttctattaca     2820

gtataaattc cttacagtgt cagtttccat ctgggaagac tctcctttct ttatctctat     2880

ctcagatggt tgtttaactg cgagtttaaa tgtgtttgtc ctggattttc ggcatgcaaa     2940

tcaaatatta ctgatcaatt cagttagtgg ccatgacatc tcaatcttgt acttcaaaga     3000

ctgagaagct ggatttaatc atccctgccc tacatatata aacataaggt aacctactga     3060

attttatgtc ccttagttct ttattacctt acataaaaat gaaaattgcg gcaggatgca     3120

tgtctgtctg ttctatctag agatcaccca tatacctata tatgtttgta tctatgactt     3180

atctaatctg cctatcaatc tatctagtag ctatctatat attttcaaaa gatagcttat     3240

gtctaaaaca gtggtgatga gtaaggccag ttgagcattg cttacttatg gttaaagtgc     3300

ttcttaaaag aaccatagtc catttacaat tttggaaggc aaaggctgat ttgtttgctg     3360

tatatagttc aattcataat tatcgcaatt atccataaca tttatatagc ggtgtaataa     3420

ctgcagcagt tctgaaatga tgctatggga aaaaaattgc aaaatatgta tttttaaagt     3480

tcatgatttg taggcaaaga tgttaagagc attgtttcca ttaaaatcaa taacaatgaa     3540

aaacggttgt ttgctttgtg ataaaatgtt aacaatccat ttaatcttca gtgaagcaac     3600

tcatttggac aaacagttct tttacagtgg ttatatggaa aagaaattga ttgctatttt     3660

ggggggctgg agtgggtaga gtattgagac cttttttatt agggtgctgt ttgttattga     3720

gagcccaatc tctgcatgaa taacagaaag gtggacataa ggaattgtaa agtatttaga     3780

atgtattgaa taggcttaag tacctccttt aaggggcaat gctctaggtt tttggtggca     3840

gtcaatttgg tattatatat gatcattttc aattctagaa ttttgtttat tgttcttttt     3900

gaagaaataa agtcttggca catcttattt atgttataa                            3939


<210>  2673
<211>  6067
<212>  DNA
<213>  homo sapiens

<400>  2673
aaaggggggg aacctagagt cggtgggggg gaagcgatgt ttgcccgtca gtcgagtccg       60

gagtgaggag ctcggtcgcc gaagcggagg gagactcttg agcttcatct tgccgccgcc      120

acggccaccg cctggacctt tgcccggagg gagctgcaga gggtccatcg ccgccgtcct      180

ctggagggca gcgcgattgg gggcccggac ctccagtccg ggggggattt ttcgtcgtcc      240

ccctcccccc aaccagggag cccgagcggc cgccaaacaa aggtaccagt cgccgccgcg      300

ggaggaggag gagccggagc ctctgcctca gcagccgctg gacccgccgc ccttcttccc      360

catctctccc ccgggcctgc tggttttggg ggggagaagg agagagggga ctctggacgt      420

gccagggtca gatctcgcct ccgaggaagg tgcagctgaa cctggtgttt tagaggatac      480

cttggtccca gagtcatcat gaaggccctt gatgagcctc cctatttgac agtgggcact      540

gatgtgagtg ctaaatacag aggagccttt tgtgaagcca agatcaagac agcaaaaaga      600

cttgtcaaag tcaaggtgac atttagacat gattcttcaa cagtggaagt tcaggatgac      660

cacataaagg gcccactaaa ggtaggagct attgtggaag tgaagaatct tgatggtgca      720

tatcaggaag ctgttatcaa taaactaaca gatgcgagtt ggtacactgt agtttttgat      780

gacggagatg agaagacact gagacgatct tcactgtgcc tgaaaggaga gaggcatttt      840

gctgaaagtg aaacattaga ccagctccca ctcaccaacc ctgagcattt tggcactcca      900

gtcataggaa agaaaacaaa tagaggaaga agatctaatc atataccaga ggaagagtct      960

tcatcatcct ccagtgatga agatgaggat gataggaaac agattgatga gctactaggc     1020

aaagttgtat gtgtagatta cattagtttg gataaaaaga aagcactgtg gtttcctgca     1080

ttggtggttt gtcctgattg tagtgatgag attgctgtaa aaaaggacaa tattcttgtt     1140

cgatctttca aagatggaaa atttacttca gttccaagaa aagatgtcca tgaaattact     1200

agtgacactg caccaaagcc tgatgctgtt ttaaagcaag cctttgaaca ggcacttgaa     1260

tttcacaaaa gtagaactat tcctgctaac tggaagactg aattgaaaga agatagctct     1320

agcagtgaag cagaggaaga agaggaggag gaagatgatg aaaaagaaaa ggaggataat     1380

agcagtgaag aagaagaaga aatagaacca tttccagaag aaagggagaa ctttcttcag     1440

caattgtaca aatttatgga agatagaggt acacctatta acaaacgacc tgtacttgga     1500

tatcgaaatt tgaatctctt taagttattc agacttgtac acaaacttgg aggatttgat     1560

aatattgaaa gtggagctgt ttggaaacaa gtctaccaag atcttggaat ccctgtctta     1620

aattcagctg caggatacaa tgttaaatgt gcttataaaa aatacttata tggttttgag     1680

gagtactgta gatcagccaa cattgaattt cagatggcat tgccagagaa agttgttaac     1740

aagcaatgta aggagtgtga aaatgtaaaa gaaataaaag ttaaggagga aaatgaaaca     1800

gagatcaaag aaataaagat ggaggaggag aggaatataa taccaagaga agaaaagcct     1860

attgaggatg aaattgaaag aaaagaaaat attaagccct ctctgggaag taaaaagaat     1920

ttattagaat ctatacctac acattctgat caggaaaaag aagttaacat taaaaaacca     1980

gaagacaatg aaaatctgga tgacaaagat gatgacacaa ctagggtaga tgaatccctc     2040

aacataaagg tagaagctga ggaagaaaaa gcaaaatctg gagatgaaac gaataaagaa     2100

gaagatgaag atgatgaaga agcagaagag gaggaggagg aggaagaaga agaagaggat     2160

gaagatgatg atgacaacaa tgaggaagag gagtttgagt gctatccacc aggcatgaaa     2220

gtccaagtgc ggtatggacg agggaaaaat caaaaaatgt atgaagctag tattaaagat     2280

tctgatgtcg aaggtggaga ggtcctttac ttggtgcatt actgcggatg gaatgtgaga     2340

tacgatgaat ggattaaagc agataaaata gtaagacctg ctgataaaaa tgtgccaaag     2400

ataaaacatc ggaagaaaat aaagaataaa ttagacaaag aaaaagacaa agatgaaaaa     2460

tactctccaa aaaactgtaa acttcggcgc ttgtccaaac caccatttca gacaaatcca     2520

tctcctgaaa tggtatccaa actggatctc actgatgcca aaaactctga tactgctcat     2580

attaagtcca tagaaattac ttcgatcctt aatggacttc aagcttctga aagttctgct     2640

gaagacagtg agcaggaaga tgagagaggt gctcaagaca tggataataa tggcaaagag     2700

gaatctaaga ttgatcattt gaccaacaac agaaatgatc ttatttcaaa ggaggaacag     2760

aacagttcat ctttgctaga agaaaacaaa gttcatgcag atttggtaat atccaaacca     2820

gtgtcaaaat ctccagaaag attaaggaaa gatatagaag tattatccga agatactgat     2880

tatgaagaag atgaagtcac aaaaaagaga aaggatgtca agaaggacac aacagataaa     2940

tcttcaaaac cacaaataaa acgtggtaaa agaaggtatt gcaatacaga agagtgtcta     3000

aaaactggat cacctggcaa aaaggaagag aaggccaaga acaaagaatc actttgcatg     3060

gaaaacagta gcaacagctc ttcagatgaa gatgaagaag aaacaaaagc aaagatgaca     3120

ccaactaaga aatacaatgg tttggaggaa aaaagaaaat ctctacggac aactggtttc     3180

tattcaggat tttcagaagt ggcagaaaaa aggattaaac ttttaaataa ctctgatgaa     3240

agacttcaaa acagcagggc caaagatcga aaagatgtct ggtcaagtat tcagggacag     3300

tggcctaaaa aaacgctgaa agagcttttt tcagactctg atactgaggc tgcagcttcc     3360

ccaccgcatc ctgccccaga ggagggggtg gcagaggagt cactgcagac tgtggctgaa     3420

gaggagagtt gttcacccag tgtagaacta gaaaaaccac ctccagtcaa tgtcgatagt     3480

aaacccattg aagaaaaaac agtagaggtc aatgacagaa aagcagaatt tccaagtagt     3540

ggcagtaatt cagtgctaaa tacccctcct actacacctg aatcgccttc atcagtcact     3600

gtaacagaag gcagccggca gcagtcttct gtaacagtat cagaaccact ggctccaaac     3660

caagaagagg ttcgaagtat caagagtgaa actgatagca caattgaggt ggatagtgtt     3720

gctggggagc tccaagacct ccagtctgaa gggaatagct cgccagcagg ttttgatgcc     3780

agtgtgagct caagcagtag taatcagcca gaaccagaac atcctgaaaa agcctgtaca     3840

ggtcagaaaa gagtgaaaga tgctcaggga ggaggaagtt catcaaaaaa gcagaaaaga     3900

agccataaag caacagtggt aaacaacaaa aagaagggaa aaggcacaaa tagtagtgat     3960

agtgaagaac tttcagctgg tgaaagtata actaagagtc agccagtcaa atcagtttcc     4020

actggaatga agtctcatag taccaaatct cccgcaagga cgcagtctcc aggaaaatgt     4080

ggaaagaatg gtgataagga tcctgatctc aaggaaccca gtaatcgatt acccaaagtt     4140

tacaaatgga gttttcagat gtcggacctg gaaaatatga caagtgccga acgcatcaca     4200

attcttcaag aaaaacttca agaaatcaga aaacattatc tgtcattaaa atctgaagta     4260

gcttccattg atcggaggag aaagcgttta aagaagaaag agagagaaag tgctgctaca     4320

tcctcatcct cctcttcacc ttcatccagt tccataacag ctgctgttat gttaacttta     4380

gctgaaccgt caatgtccag cgcatcacaa aatggaatgt cagttgagtg caggtgacag     4440

caggacttgc taaagcactt tgcacttaat ggctgttgag ggccactttt tttttatact     4500

gcacagtggc acaaaaaaat atcagacaag cactatttta tatttaaaaa ttgtttcttg     4560

acaagctgac ttggcactta agtgcacttt tttatgaaga aaaagtacaa tgaactgctt     4620

ttcctcaagc aataattgtt tccaacttgt ctgggaattg tgtgtctggt aactggaagg     4680

ccttccactg tggcaaatgg aggcttttca ctgcctgtag agacaataca gtaagcatag     4740

ttaaggggtg ggtcagaaca tgttaagata acttactgta tatgtattcc cttgtatttt     4800

gttaaagctg gaacatttga tatttttcca tttatttatg aaaaaatatg aacctatttt     4860

catttgtaca aggtaattgt tttttaaagc aagtcacctt agggtggctt taattgtata     4920

agtcaagcac atgtaataaa ttcaaaacct gcagttaaca ggatattaga catcaatcct     4980

ggtaaccaaa tattaaagat tctctttaaa aaagactgaa catgtttaca ggtttgaatt     5040

aggctaaaag gtcttgcagt ggcttttcat ggcccttcaa attggaatgg aactactgta     5100

ctttgccatt tttctataaa tcagtatttt tttttaattt tgatatacat tgtgtgaaaa     5160

aagaaaatgg ctaataaact gtattaaatc ttaaacaatg tataaagatt gtacttagcc     5220

agttcaaagt gtatatttat tcataatgaa ttataacagt tatatttttg tgttttcttg     5280

taaatgtttc ttttccctta aatacagata attcatttgt attgcttatt ttattatgag     5340

ctacaacaaa aggacttcag gaacaagtaa tgtattagta tggttcaaga ttgttgatag     5400

gaactgtctc aaaaggatgg tggttatttt aaatataaat agctaatggg ggtggtaggc     5460

ctataaaatt aaatgccttg tataaaatcc aaaatgaatg caaaattgtt ttcacttgta     5520

ttgactttat gttgtatgat tccaatctct gttctgtttg gcacttgtat ttaattcttc     5580

acctttgtaa gacatttgta tattgtggat gtgttcattc aagctattta atatctggca     5640

ctgttaatac acagtacttt attgtacaga ctgttttact gttttaattg tagttctgtg     5700

tacttttttt ggatggggct ggcatgtttt ctttgtttcc tggcaatacg acgtgggaat     5760

ttcaatgcgt tttgttgtag atgctaacgt gtcagaatcc tttacattca acttttctaa     5820

gaaaagcatt ttcagtcttg tagtgtgtgc ttacagtaac taattttgtt gaaaatggtt     5880

tcaagttatt caaatttgta caggactgta aagatttgtt gacagcaaaa tgttgaagaa     5940

aaaagcttat agaataaaag ctataaagta tatattagga tctgcaaaca atgaagaatt     6000

atgtaatata ttgtacaaat gtaagcaaag gctctgaaat aaaatgccat agtttgtgaa     6060

tccttga                                                               6067


<210>  2674
<211>  8787
<212>  DNA
<213>  homo sapiens

<400>  2674
ggccgcagct ccccggcgga ggcaagaggt ggttgggggg gaccatggct gacgttttcc       60

cgggcaacga ctccacggcg tctcaggacg tggccaaccg cttcgcccgc aaaggggcgc      120

tgaggcagaa gaacgtgcac gaggtgaagg accacaaatt catcgcgcgc ttcttcaagc      180

agcccacctt ctgcagccac tgcaccgact tcatctgggg gtttgggaaa caaggcttcc      240

agtgccaagt ttgctgtttt gtggtccaca agaggtgcca tgaatttgtt actttttctt      300

gtccgggtgc ggataaggga cccgacactg atgaccccag gagcaagcac aagttcaaaa      360

tccacactta cggaagcccc accttctgcg atcactgtgg gtcactgctc tatggactta      420

tccatcaagg gatgaaatgt gacacctgcg atatgaacgt tcacaagcaa tgcgtcatca      480

atgtccccag cctctgcgga atggatcaca ctgagaagag ggggcggatt tacctaaagg      540

ctgaggttgc tgatgaaaag ctccatgtca cagtacgaga tgcaaaaaat ctaatcccta      600

tggatccaaa cgggctttca gatccttatg tgaagctgaa acttattcct gatcccaaga      660

atgaaagcaa gcaaaaaacc aaaaccatcc gctccacact aaatccgcag tggaatgagt      720

cctttacatt caaattgaaa ccttcagaca aagaccgacg actgtctgta gaaatctggg      780

actgggatcg aacaacaagg aatgacttca tgggatccct ttcctttgga gtttcggagc      840

tgatgaagat gccggccagt ggatggtaca agttgcttaa ccaagaagaa ggtgagtact      900

acaacgtacc cattccggaa ggggacgagg aaggaaacat ggaactcagg cagaaattcg      960

agaaagccaa acttggccct gctggcaaca aagtcatcag tccctctgaa gacaggaaac     1020

aaccttccaa caaccttgac cgagtgaaac tcacggactt caatttcctc atggtgttgg     1080

gaaaggggag ttttggaaag gtgatgcttg ccgacaggaa gggcacagaa gaactgtatg     1140

caatcaaaat cctgaagaag gatgtggtga ttcaggatga tgacgtggag tgcaccatgg     1200

tagaaaagcg agtcttggcc ctgcttgaca aacccccgtt cttgacgcag ctgcactcct     1260

gcttccagac agtggatcgg ctgtacttcg tcatggaata tgtcaacggt ggggacctca     1320

tgtaccacat tcagcaagta ggaaaattta aggaaccaca agcagtattc tatgcggcag     1380

agatttccat cggattgttc tttcttcata aaagaggaat catttatagg gatctgaagt     1440

tagataacgt catgttggat tcagaaggac atatcaaaat tgctgacttt gggatgtgca     1500

aggaacacat gatggatgga gtcacgacca ggaccttctg tgggactcca gattatatcg     1560

ccccagagat aatcgcttat cagccgtatg gaaaatctgt ggactggtgg gcctatggcg     1620

tcctgttgta tgaaatgctt gccgggcagc ctccatttga tggtgaagat gaagacgagc     1680

tatttcagtc tatcatggag cacaacgttt cctatccaaa atccttgtcc aaggaggctg     1740

tttctatctg caaaggactg atgaccaaac acccagccaa gcggctgggc tgtgggcctg     1800

agggggagag ggacgtgaga gagcatgcct tcttccggag gatcgactgg gaaaaactgg     1860

agaacaggga gatccagcca ccattcaagc ccaaagtgtg tggcaaagga gcagagaact     1920

ttgacaagtt cttcacacga ggacagcccg tcttaacacc acctgatcag ctggttattg     1980

ctaacataga ccagtctgat tttgaagggt tctcgtatgt caacccccag tttgtgcacc     2040

ccatcttaca gagtgcagta tgaaactcac cagcgagaac aaacacctcc ccagccccca     2100

gccctccccg cagtgggaag tgaatcctta accctaaaat tttaaggcca cggccttgtg     2160

tctgattcca tatggaggcc tgaaaattgt agggttatta gtccaaatgt gatcaactgt     2220

tcagggtctc tctcttacaa ccaagaacat tatcttagtg gaagatggta cgtcatgctc     2280

agtgtccagt ttaattctgt agaagttacg tctggctcta ggttaaccct tcctagaaag     2340

caagcagact gttgccccat tttgggtaca atttgatata ctttccatac cctccatctg     2400

tggatttttc agcattggaa tcccccaacc agagatgtta aagtgagcct gtcccaggaa     2460

acatctccac ccaagacgtc tttggaatcc aagaacagga agccaagaga gtgagcaggg     2520

agggattggg ggtgggggag gcctcaaaat accgactgcg tccattctct gcctccatgg     2580

aaacagcccc tagaatctga aaggccggga taaacctaat cactgttccc aaacattgac     2640

aaatcctaac ccaaccatgg tccagcagtt accagtttaa acaaaaaaac ctcagatgag     2700

tgttgggtga atctgtcatc tggtaccctc cttggttgat aactgtcttg atacttttca     2760

ttctttgtaa gaggccaaat cgtctaagga cgttgctgaa caagcgtgtg aaatcatttc     2820

agatcaagga taagccagtg tgtacatatg ttcattttaa tctctgggag attatttttc     2880

catccagggt gccatcagta atcatgccac tactcaccag tgttgttcgc caacacccac     2940

ccccacacac accaacattt tgctgcctac cttgttatcc ttctcaagaa gctgaagtgt     3000

acgccctctc cccttttgtg cttatttatt taataggctg cagtgtcgct tatgaaagta     3060

cgatgtacag taacttaatg gaagtgctga ctctagcatc agcctctacc gattgatttt     3120

cctcccttct ctagccctgg atgtccactt agggataaaa agaatatggt tttggttccc     3180

atttctagtt cacgttgaat gacaggcctg gagctgtaga atcaggaaac ccggatgcct     3240

aacagctcaa agatgttttg ttaatagaag gattttaata cgttttgcaa atgcatcatg     3300

caatgaattt tgcatgttta taataaacct taataacaag tgaatctata ttattgatat     3360

aatcgtatca agtataaaga gagtattata ataattttat aagacacaat tgtgctctat     3420

ttgtgcaggt tcttgtttct aatcctcttt tctaattaag ttttagctga atcccttgct     3480

tctgtgcttt ccctccctgc acatgggcac tgtatcagat agattacttt ttaaatgtag     3540

ataaaatttc aaaaatgaat ggctagttta cgtgatagat taggctctta ctacatatgt     3600

gtgtgtatat atatgtattt gattctacct gcaaacaaat ttttattggt gaggactatt     3660

tttgagctga cactccctct tagtttcttc atgtcacctt tcgtcctggt tcctccgcca     3720

ctcttcctct tggggacaac aggaagtgtc tgattccagt ctgcctagta cgttggtaca     3780

cacgtggcat tgccgcagca cctgggctga cctttgtgtg tgcgtgtgtg tgtgtttcct     3840

tcttcccttc agcctgtgac tgttgctgac tccaggggtg ggagggatgg ggagactccc     3900

ctcttgctgt gtgtactgga cacgcaggaa gcatgctgtc ttgctgcctc tgcaacgacc     3960

tgtcgtttgc tccagcatgc acaaacttcg tgagaccaac acagccgtgc cctgcaggca     4020

ccagcacgtg cttttcagag gctgcggact ttcttccagc cattgtggca ttggcctttc     4080

cagtcttggg aggagcgcgc tgctttggtg agacaccccc atgcaaggtc ctcagagtag     4140

ccgggttcta ccacaaacag aaacagaatg aaagtagctg tcagtccttg tagagagccg     4200

ctctgtttcc tcccagaagc atctcccagc taagctcgca ttatttttct cctctggctg     4260

tttgcctgaa gttcacagaa cacacaacca tgaaaggctt tttgaggtga gaggcccagg     4320

tggtcctggc aaccctgagt agaaggagag acggggtagg gaacgggccc ggccagaaaa     4380

gaaccatttc ttctgccatc ttttatgcac catagacatc gagactccag ggggtcctgg     4440

ctcccctgtc cctgcagccc tgcaggtcag tgcatgatct gggttcgtgt cctgaccagg     4500

tgctcctcct ttgatccgag gggaaaggga ctggtttata gaaagagcct aggagacaaa     4560

agggccagtc cccctgccca gaatggagca gcagcaggac agacccccac gaggcccccc     4620

agagaggagg aagatcccac ggaggaacac atgaggttag ggacccttgt tcagcacccc     4680

aaacagcctg cctgtttaaa gcaggcagca ggcttaggcc ttccctgcaa ccccaacacc     4740

cacaagtttg tttctctagg aaacacattc actgtctcag ctggctgtta ctctctcaga     4800

ccatatggca aagttttcca agaaaatgcc ccgacagggg tgcccagcac actgcctgag     4860

ggacaacaga catcagaaca aacccccaga gagaaacagt caaaatcagg gcccggtgca     4920

gtgttgtcat gtggaacctg ctttatccat tgctgagtgt tgaatgtggg taatggttag     4980

ggctttccag atctcagcag ccaaagacag ttattgttgg aagactgtca tgtagataac     5040

catgagcaat ggctcgcctc agaatcagtt cataaaattc tatggtactg gccccttcgt     5100

gggtattgtg tgaaatgaga tggtggcgag gggtgcgctg tggaactgcc gcagccacgc     5160

aggaggtccc tgggggatgc tttgggaagt ccttgcccct gagcactgcc tgattgccag     5220

ggcctgtgga ggtctaggcc gcctggcaga atctagcacc gtccgaatcc ccgcaggacc     5280

catggagcta tgaccacacc aggccattca aatggctctg cattatcttc ccttggaagg     5340

tggccactcc tcggtggcag ggcctttccc tgaggctgca ggccgtgggc tggcagcccg     5400

tctcttggca tttcaattga aggtcaccag gtgctgggtt tgaaaggaag tcactggagt     5460

gctgccaggg gccgccctcc aaggttaatg agaggcccac atccaggcaa gaactaattc     5520

aaaaggcaga tcagaaacca caggagtcaa aattattgct ccggcagtgc ttcccttcct     5580

ttcatccact ggcctcgtgt ggtccatgca gggccactgt ctgccctttc tgatgccacg     5640

tattaggctt tcttactcag aattttgata gaaaaccatg gggccaagag ctctggaagc     5700

ctggccggaa agaccaaggt tcatgcagcc caacaaatga ttgttgagca cctctcggag     5760

ccaaagtcct taggcgagtg tggtgacttc ctggaaggag gatgcagact tccagagagc     5820

ccccccaacg gacgtgctga gaagggagag ggaggcgggg gctgtagtca ggaaggagcc     5880

agagaagaac agggtttggg tgcatccaga aatatgcctg cagtaggagg gagaggaagg     5940

ggtgccaccg tcaacggctt cccatcggag gtggttggtg cagatggaag tttctgtctg     6000

ctggccctca agagagtgtt ttgccaggga cacagtctgt tcctcctcag aaaacacccc     6060

ccaaatgcta acaacatccc caccagctgc tagaagcccc tttcccctcc ccaccttgaa     6120

gtagctcata gttctctggg cagagccaga ccatccagtg taccccagag gccagtaggt     6180

tcctgcccat tttcctctct ggcttcctgc caagaattat ggcagctgag gatgaatgga     6240

gaagtaaaaa caactaacac cgcacaacta acaactaaca ccgcagttcc cacctgggtt     6300

ccacttagca ggagacattt cggagggttt tttttgtttt tgttcctgtt tttttttttt     6360

ttgctggaat ttgttttctc agtactgaaa agagaaaaag tgacaatctt gtatttttaa     6420

aagcctcgga aaggtgatac catctgacag tcattttctc acgttggtct tctaaagtca     6480

cctatttctt gtgtgtgcac atcacaccat ttcctgtttc tttataaccc gacaagggta     6540

ggagtgcctg tttcccctgc tgggcacacc agacaatcgt aatcacaaaa cagacactga     6600

gccaggggcc caaagggtgt gatcatgaga gttaccggga cagcagtagg catgacagtc     6660

accaggaagg acaagggtgc tctgttgtta gtggccacac accaatttga caaggagtgt     6720

tgcgaaattt ttatttattt atttatttat tttgagatgg agtttcactc ttgttgccca     6780

ggctggagtg cggtggtaca atctcggctc actgcaacct ccacctccca ggttcaagcg     6840

attctcctgc ctcagcctcc caagtacctg ggactacagg tgcgtgccac cacacccagc     6900

taaattttgt gtttttagta gagatggggt ttcaccatgt tggccaggat ggtcttgaac     6960

ccctgacctc atgatctgcc tgcctcggcc tcccaaagtg ctgggattac aggcatgagc     7020

caccacgccc agccaaaata tttttttaaa gtcattttcc ttaagctgct tgggctacat     7080

gtgaaataca ctggacggtc aacattcctg tctcctccca tttgggctga tgcagcagat     7140

ccagggaatg ttacctgttt ctgctgctag aagatccagg aaattgggaa ggttacctga     7200

cgcacacatg gatgaaggcc atcatctaga aatggggtca accacaattg tgttaattcc     7260

gtagtgtcag ggattcttcg ggaaggtcaa cagtatgaag gattctgacc cctgtgcctc     7320

ccatttatgt gatcaggtga cagttaataa ccgtggaggt cacactcagc catccaacag     7380

ccttacagtg accctacaca aaagccccca aattccaaag actttttctt aacctaaagg     7440

aagaaattat ttgttaattc cagtagagca actgaatata ctgggctatt tgtacttttt     7500

tatagagaac tttaataata attctttaaa aatgagtttt tagaacaaag caactgacga     7560

tttcctaaga ttccaatgcc ctggagcttg taggaggact tagcctgggt cagctggagc     7620

acccccgacc tgatctccca ctgccagatt ttcccatgct cctagggtat ggagtccacg     7680

tgggaatgac tgcaagttca ggtggaactt ggccgactga tgctctgcga gtttttaata     7740

gacactgggg acaactgctt aaggtttaga aacttccaaa ccacaggaaa gacattttta     7800

gtgtccccca tccagaggca gccctggaat aggattccca ggggtttctg ggaccccttt     7860

ccttgctccg tgaggctctg tggccatctt ttggcaggag gaggatgctt ccttggctct     7920

gtgcccagac ccgcctggtc cccaggtctc tcaccttggg tgaagattca gagatgccct     7980

gtaaggattt tgcccactgg gcaactcaga aatacttcga tctcccaaga tataagaggc     8040

agcagcaaac gtgcctattg acgtctgttt catagttacc acttacgcga gtagacagaa     8100

ctcggctttt cagaaaatag gtgtcaagtc cactttataa gaaccttttt ttctaaaata     8160

agataaaagg tggctttgca ttttctgatt aaacgactgt gtctttgtca cctctgctta     8220

actttaggag tatccattcc tgtgattgta gacttttgtt gatattcttc ctggaagaat     8280

atcattcttt tcttgaaggg ttggtttact agaatattca aaatcaatca tgaaggcagt     8340

tactattttg agtctaaagg ttttctaaaa attaacctca catcccttct gttagggtct     8400

ttcagaatat cttttataaa cagaagcatt tgaagtcatt gcttttgcta catgatttgt     8460

gtgtgtgaag gacataccac gtttaaatca ttaattgaaa aacatcatat aagccccaac     8520

tttgtttgga ggaagagacg gaggttgagg tttttccttc tgtataagca cctactgaca     8580

aaatgtagag gccattcaac cgtcaaacac catttggtta tatcgcagag gagacggatg     8640

tgtaaattac tgcattgctt tttttttcag tttgtataac ctctaatctc cgtttgcatg     8700

atacgctttg ttagaaacat taattgtagt ttggaagcaa gtgtgtatga ataaagataa     8760

tgatcattcc aaaaaaaaaa aaaaaaa                                         8787


<210>  2675
<211>  10390
<212>  DNA
<213>  homo sapiens

<400>  2675
gtgcgaagcg tgaggtggag atgggggcgg agggagctgg agctgtcaca gtccccgggt       60

gcgcctgacc gagccaagtg gggtgtcatg gccgcggggg gcagcggctg cacttcctca      120

gcgggcggcg gtggccgggg agttaatcct cgacgcacgg gtcccgtttc cctctgtgcg      180

gcggccggcg ggaccataag ggcttaactc atatatttaa cccccctcca aaaaggtttg      240

aaagtattct tgaagggctg tttggacctg cattattaaa agatctcagt ttatttaaag      300

actgtgaacc tgaaagcatt tctgattgga cttttgatga aaactgttta ttctgttgct      360

tgagaagaga taaagtaaag ggacacttag tcggtctgga tgaaccagct tcgggagctg      420

ggcaagaagc tctgcttaaa caagagcaag caaaaatcat tcgattcgag agacaagcag      480

aagaattcct caatgcagtc ttttatagaa aagacagtcc ctgggtctcc gaccccaata      540

ttcccctagt ggcccgtgag atcatgcagc gaatgatcca acaatttgct gctgaatata      600

cctcaaaaaa tagctctact caggacccca gccagcccaa tagcacaaag aaccaaagcc      660

tgccgaaagc atctccagtc accacctctc ccacggctgc aactactcag aaccctgtgc      720

tcagcaaact tctcatggct gaccaagact cacctctgga ccttactgtc agaaagtctc      780

agtcagaacc tagcgaacaa gacggtgtac ttgatctgtc cactaagaaa agtccatgtg      840

ctggcagcac ttccctgagc cactctccag gctgctccag tactcaaggg aacgggcgac      900

ctgggagacc cagccagtac cgcccagacg gacttcggag tggtgatggg gtacctccaa      960

gaagcttaca ggatggaacc agggaaggtt ttggacactc cacatcactc aaagttccac     1020

tggctcgatc cctgcagatt agtgaagaac tactgagcag aaaccaattg tccacagctg     1080

ccagccttgg gccatctgga ttacagaatc atggacaaca cttaatatta tccagggaag     1140

cctcttgggc aaaaccacat tacgagttca acctcagccg tatgaagttc aggggaaatg     1200

gtgcactcag caacatcagt gaccttcctt ttcttgcaga aaactctgcc tttccaaaaa     1260

tggcacttca agcaaaacaa gatggaaaaa aggatgtgag ccattcatct cctgtagatt     1320

taaagatacc acaagttcga ggaatggatc tttcttggga gtctcgcact ggtgatcagt     1380

acagctatag ctctttggta atgggttcac aaacggagag cgcgcttagt aaaaaattaa     1440

gggctattct tccaaaacaa agtagaaaaa gcatgttaga tgctggaccc gattcttggg     1500

gctcagatgc tgagcagtct acctctggac agccatatcc cacatcggat caagaaggag     1560

accctggctc caagcagcct cggaagaaaa gagggcgtta cagacagtac aacagtgaga     1620

tactggagga agcaatctca gtggttatga gtggaaaaat gagtgtttcc aaagctcaga     1680

gtatttatgg gattccccac agtacactgg agtacaaagt aaaggagagg ctgggcactt     1740

tgaaaaaccc tccaaagaaa aagatgaaat taatgaggtc ggaggggcca gatgtttctg     1800

taaagattga attagatccc cagggagagg cagcacaaag tgcaaatgaa tcaaaaaacg     1860

agtaggaata ctgtagagtg ccaattactg tacaaactgg gtgagcacta ctgcatcatt     1920

gttcagctat cattgcttgc acgtaatttc atttactgtg acacttgctt ctttgcagat     1980

tttgcattga cttgtgtgta cagagatgaa atgtgcattc tgaatgttgc atattttaaa     2040

tttttcatgt gcagtatggc tcggaatatg tttggccttt tgcatgtttc tctacaaaag     2100

agaattgagt tacctcacag agaacagata catggaagtg gactccttgc ctgtagagcc     2160

tgcatgcttt tttgtttttt tttgttgttg ttgttttttc ttaagttata tttgttttta     2220

ctttttaaaa aagaagagga aacaaagccc ccttttagaa actacgtctg tcatactggg     2280

agctttatca ctgcaaattg gaaagccatc ttatacaaaa ttattcacat ttttcatcta     2340

cgattcaact aatcgaagga ttaaactaaa gaaaaaacta agaagaacaa tgaacctttg     2400

actttgagaa atttggttat tcactgacat aattattggg tcatttatag ttacatttta     2460

taattttctt ctcactatta aatttattta aattagcaag ctattagtgc tcacccagag     2520

gggaaggtgg tggaaaatgt gcacacacta ccttcagaaa tgcttcagtt aattactttg     2580

aacactacct ttgctgtaat ttcatttgag attttctaag ggtagaattt ggtctcacca     2640

acaagtgagg atatagcctt atctcatgga ggacgagctc cgtatttact caggagcagt     2700

cagggtacat tacataaaac aatggaggat gcctcatttt agcaaactag gtttctttgt     2760

attcttcagt ccttttacag aattgatgtg ctaactgaat atcattgcag caactagact     2820

aagatattca agatctcttt attggggatg ggagaaatag ggaaagaaat gtgtataagt     2880

aattatgata ttgcaaaagt gatacttaga ttttacagcc tcagtagtct gcccagtgtc     2940

cacattaatg aaggatccat gtttgtagtg agagaaaaaa accccaaggt aacccgatat     3000

gatttaggat gcatatcagt tctaacaatt caatcagaag tcaagctcat tggaattcct     3060

tttttaactg atccaaatac tagtagaagg gggagggaga ggtgttgggt ttttttttta     3120

agtttttatt taattttgtt ggttagaatt tttttctgtt tttggcatcc tacataatac     3180

cccccttctt gactttttct gataattagc tgatattcat ggttgtttag cacacagttc     3240

aggacctttg agatcatgtt tgtataagca ctccttgaag aatatctaag ctttttctga     3300

gatgggcttt taaaattata ataagggaag tttattttct gcggtttttg caagaataag     3360

caaagcccat ggaatttaat ttttcattgt gatcagatta aaattactat ttgtgcaaaa     3420

caaattccac accacatgta ctgtatattc taatctgctg agaaaggtgg tcaggccctt     3480

ctaaatgctt aaccaaaaac aaacattatt ggagtttcag tgtaaaataa aattaaaatt     3540

ggagggttgg ttagattgat ttcagatgga tactaacagt ttgaggggag gtccagatat     3600

ttccaaggca taaattcttg cctggaaact ttggagcaat taattaaatt aggttaagtt     3660

ttccctcagc aacctgtgtg ttcaaaggtt aggcacacca ttgctgttac taaaatacat     3720

gcactgctca ttcttgacat agcttgggtg tgggttcctc ttgttttggt tattttgtgt     3780

agcagtttaa tcagtggata actgagcctg tttcctctta gctttctaga cttcttaaca     3840

gaaaaaacag tttgggttca atagcatttt atgattctac aatattttgt cacctagctg     3900

gaagttgcaa taaaaattcc ttatgaaata tatggttttc atctgtaatt gaaggaaatc     3960

atagaaagtt tgctgaaagc aaagggctaa gcttatgaag gaatgcctcc tttgttacac     4020

actcaagaat ttgtcagcac acaattaatt gcagccatag tacctttttg cgtaatgttt     4080

gggatattca gtagcccagg attgctacaa aaaggtcctt tgagaaaatt aatttgtgct     4140

tgcttttatc ccctctcaga aagacatcac taaaggccca ttaaaaatct ggccctaaaa     4200

gttcaacttt tgtagagttt attgttcaga gaggtttaat cctatgtggt agtctatata     4260

agtgatgtat gagttgagtt atgtaaattt tgtcattgta gtgtacatgg agtgatcatt     4320

ttactaacat aaatattttc tatgtgtgtt tcagtggatg acaatcgagc agcagaagaa     4380

tggtgtgcct accctttaat gctgcagttt aagagaactt gtattgtgtc atttcagatt     4440

gtaggctgag agttgtaaat agtgaaaatt tgagtacttc tattatttgt tttggttaga     4500

aagtgaattt aaaaaacaaa ccaaactcta aactttctca gattaaaagt cctgagacct     4560

gaagattgta atattcatgt ctgtgaagct tttaaacatt acacttgaga tcagtcatga     4620

cttgatattc aggtaaattt tcttttccaa gaagcttttg aataagcata tttcctccaa     4680

aggtctctct ctttctctct ctttttttga gtgtagatta ttttaaagca ctaattgcat     4740

tacattggta actgcaatat aaaatagcca ttattgtttt gtgaagcatg gttgaaatta     4800

gctagtggtc ccttttgaat ttcatgagcc tctcaaaaaa gaaaaactta aaaaaaaaaa     4860

aaaaaaaaaa caaaaagctg ctggaatatt tcaaaagata tatattttac cttattatag     4920

gttttgtaaa gttagtttgt aatattcagg tgcactttta atgttaaatt ttgtgttcag     4980

agttccatta taccatgtat ttctcggagg tggctcatca cacggctggt ggcagtcttg     5040

gtgccgcagt gattccttaa tatttgattt ctctcttgat ttgccactat tctgtattgg     5100

cactttcagt gtagatattc tagtttgggg atgtcctcac aatgtgtaat agagattggt     5160

ctattagcat gcttaatttc tgctaatcag agttttgcat ggcccaaaca acagttgacc     5220

atttttatgg tatgggaaag tgtagttcac aactgtcttt gtcacgaaag ccgtttttcc     5280

tcacattttc cagtaggcag ataacattac ttaaattatt aatatataac actcttggaa     5340

ctattgatag gaaataatgt atttaaaata attttttgca ttttcagaga ccttgatgtt     5400

atagggtaga taagctatgg cactataaaa tcaaaaacac taattctgtg gaaggatatc     5460

tagttggtat ttttatcttt agctttctca tttctgagac agcatagtca tccagcttga     5520

tggtaatgta gtatattact ttgttcagtg ggcttataag tgactctgaa ttatgtttgt     5580

gatgagctat acactttttt tctgttcccc aaataccatg aaggacaagg tcactctttc     5640

aggaaaaata atttatattt gtgtataata ctttttaata ttaagtttgt tgttctgaag     5700

tttagatgtt gcttgataaa cctttgctgc agcagatcat gaatatgagt aaggctttgt     5760

gtgataatag gggtccttat gtgaagttaa ttactgttca gttctggtga gcaagctcaa     5820

caagtgtgaa gtgtgtatta gctttatttg gtacactttt actttacaat atcgaagtgc     5880

ttttagaact ctggttatct tatataaacc attacctcaa ccaattggca tttcttttcc     5940

ccaacattta ccttagctat aatatgagct atgtgggatc agatggtaaa actataaaag     6000

gcacaatgag aagtttagtt cccaagtttt ggagagaact ctaaattaga ctaaaaacaa     6060

ctacctgtta acaccaatat cataactacc ttctgtcgtt aggcagtaca tagcaacctt     6120

tgagctgcta gtgagctatc tgttctcccc ctacccccaa gtaagcacac agtgccaggc     6180

ctggttctaa gcctttgtga ttctcttaca tctcattgac ccataatagt gaagcatgga     6240

ttcatttatt ttcataagac aaattgagtc agctcgatgt cagaagttga aaatattttg     6300

agtagtttaa cagttatatg agagattggc atcattttct ttaacagctt ttatctttgt     6360

agatttcctt ttgagacatg tatttttgct tttataatcc tttcattaaa tgccagaggt     6420

tgttttcata ttaatcactc ttttctgtat attcaggttg ctgtcattgg tgatagaata     6480

tggcaataga cagaattgtg ctccacttta tgttttttag gagatattga aagttatagg     6540

ttaaattttg gccttcttga agatatcaaa gattgttttc cttgttacct ttaattagaa     6600

tttggtcttc attaatgctt tggtcaggct agcattacta aaaacttgat ggcttcagca     6660

gaacagcccg tttaggagac tattaagcta tctagggatt ttttttcaaa ttaattgctt     6720

tcaaaatctg aaaaggaaaa aagtataatt gtggtacaaa gaagacagat ctccaggctc     6780

tttcttctca gtttattttg gtttaattct gtactggaga cttgaatagg atttgtgaac     6840

atggtgatgg aaagaaaaat agaggacatt atttgtgtac cctcattcct gaataatctt     6900

gcagtcacct tttaaagaag cagacattag ccctgtaaca caacactgta gctataaact     6960

ctaagtgtta ggaaggagat tggggtgggg agggtggagt aggatggaaa aagcatgtag     7020

acttctgaga agaggctaaa aattctgccc tataatacta aaaatgagtc acaagataat     7080

gtggtgaagt taggccatct tgatttgata gaaaaatctt ttacattgtt taaaaatgag     7140

aatcgaggct aattaatgtt gatttgacaa tagaacatga gctaattctg caaccgtttg     7200

gggggtaatt ttatggtttc cagttcattt agagctgtat caagaaaagc taaaaagcaa     7260

gcacttttag ttaatcatag atttattgga tatagcaaat attattataa tatttaatct     7320

ctattatttg aatgtggaaa tgaactcttt taccccatct tgaactgtca ttgaacatgc     7380

tcaagatgat caacactgga aatgacccta cacacatacc aaaaaaatct aaagcagtaa     7440

gacatatttg aagatccata cctcttaaac tttttagatt tgtcttggga aagaatttat     7500

gaacctgtaa ccagtattag tgcagtcttg ggttccttgt tctgcataat tgcacccttt     7560

ctcaggtatg tcctgacaac ataaatttta aaataatctc attagagatt agattctcag     7620

tggatagtgt gtaaggggac taggggtggg gggttggggg tagttggaca caggacactg     7680

acacagtaga gcagggattt ttaacagtca atagccaaat agaatttcaa tctagaatat     7740

ttttaccccc tcagaatgag tgaaacaact tctattattt ggtgtacccg gtgctacact     7800

cctaaaagtc tttttttttt ttcatccagg tgacgttttt tatttttcct gcttggtggt     7860

ggaaggttat atagtaaact tcactgtcat taagaaagcg cttgtccaaa atgtttaaag     7920

tactagaaaa gggataattc agcacttttt ctgttacaac actaaagtct taatttatct     7980

tcagagtctt aggtactgta agtttttgga tgattattta aaaatataaa acatactaca     8040

taatatgggg tcagatcaca tttatataaa taattcttat tttaaaaaag acaataacat     8100

tttgtacctt tctagcaatt ccaagtgatt gcctcatttt ctcttgttaa gcatttcaag     8160

cttaagaatt tggaatttga gagaaggtga gggggaaaat tccctaaaat aaaaatttgt     8220

ttcaaaccat tttagaaaaa taaatcacta ggaaaatagg tagggattct ctcccccttt     8280

aagtcttcag ggaatgagca gtatttagaa tctttggctg aaattcaagc ctttttactt     8340

tgtaaatttt taatattaat tcactgacat gctttttaca ccagaggact gaaaatggat     8400

cttaatgttt ttaagttgtg gaagggtata tttctaaaat gaggggggat gattaactag     8460

gttagtatta ccagcattag taagtttaag gaattttagt atgtaatagc aaagtgtttg     8520

attaaaagtc taatcctata ttactagtca aaattagtta cattctgatc taggaaagat     8580

aatagtcatt ggatattgat atgctgtgct gtcagaaaac cagactaaga tagaaacctt     8640

tatctgactc ccacatgttg cttgttgtga tgggatgtat actttacagc agcttattgc     8700

tgctttgaaa aaaaatgtat aaactataca tttggagtgt ttgcatataa ttctttataa     8760

cctccactta aagctgtcag acattggtat tttatcagtc cacattgttg aataaaacta     8820

atgttcttag gaatccagct tgtacacact gtttaaaaac cctcagggac agtttacaca     8880

ctcttctcac tcaattcagg tactttgatg ctattcttaa acctaacagt gacttgtatt     8940

tttctgtttt gcttttattt caacgtgctg gtagcacatc tgatgaatgt caacttaaaa     9000

aactcagttc aggtatccag gtataactca gccaaacaga ttttaaagct gcatataact     9060

ctccagcaca tggtgcctca cactcttata gtggcattct atatattcag ttattactac     9120

tgagcagata atatgggggt tcctgttaac agtgtatttt ttaaaaaaag cgcataaatg     9180

tatagccagc acactacaca cacacacaca aacatgcaca gttaaactat atatttttaa     9240

atgccactaa tagccagcac aactaaaaca aaagacattc ctaactgctc tgtaagctgt     9300

taacagatgc agttccttct tgatgtggct cttgcttctt cacgataact actactaaat     9360

tcaagcactg gtccttgggt gtctgacctc tacattctag tttatgcaat gtctttagag     9420

aattttgtgc actggccact gtgatggaac cattgggcca ggagtgcttt gagtttatca     9480

gtagtgattc tgccaaagtt ggtgttgtaa catgagtatg taaaatgtca aaaaaattag     9540

cagaggtcta ggtctgcata tcagcagaca gttttgtccg tgtattttgt agccttgaag     9600

ttctcagtga caagtttttt ctgatgcgaa gttctaattc cagtgtttta gtcctttgca     9660

tctttaatgt taagacttgc ctctttaaaa ttgcttttgt tttctgcagt actatctgtg     9720

gttaacaaaa tagattattt ctctgcttta atatttgata tcttacatct aaaataaatt     9780

ctctccacat ataaaaccca tagcctttgg agatatggaa aatggtatct ttcagatttc     9840

tagaagttca agtgtcatac aacaaaacag gaaccccctt tactcttatg gacctcattt     9900

caatatactg tttacagttt gatggaattg tataatttaa tatttctctt gtactgtagt     9960

ttatatttat ttacagattt ttttgtactg tgtgatttga actttttgtt ccttgctatg    10020

atcaatgttt atgtagtaga gcacttatga tcacaaatta agttttttgg tttgattgca    10080

ctacattaaa ttttttaatg cagttctgat ttttgactgg actaaaactg tgtcttaatg    10140

tatgtgatga gtacttaaaa ttttaatcca tgtggtcccc cccctttttt ttttttttgc    10200

attgtatgtc aaaagcgctt gttctttcgt gcatgtgtaa gatttaatgg ttccattgta    10260

ttatttgacc atgacatttt ggagaaacat tcccagctgt aatgttgtgt atggtagttc    10320

tcactggatg ctagagtttt caaaaccact attcttctaa taaattttgt tgtgaaaaac    10380

tgttaaaaaa                                                           10390


<210>  2676
<211>  4194
<212>  DNA
<213>  homo sapiens

<400>  2676
tgacccaccg gccttgagga aagcgcaaac gtaaaaaaag attgaaaccg gagaggcgaa       60

tgcatctgtt tacgctagga ccacgctcga cgtcggagaa aagcccacac actcacagtt      120

tccagacctg gctgcttgcc gaaactcaga ttctcggcac ctccagcagc tggcttcgcc      180

aacggcgttg aacaagggtc gcagctcaat gacgtcatat ctccctacct acctccaggg      240

ttccgcctca cgctctatgt cgcgcgcgcg cactacgtcc tatggcttgc gcgtgcggcg      300

gctgggcacc gccattttgg ccggtggccg tgagaacacg ctgtgtggct gaaaagtgaa      360

ggcaagagct gatttggcct ctgtgctccc ctccgcaagg ggatcgtttt ctccagaaga      420

gctggatatt ctttcgccca gttatggcag acaagttaac gagaattgct attgtcaacc      480

atgacaaatg taaacctaag aaatgtcgac aggaatgcaa aaagagttgt cctgtagttc      540

gaatgggaaa attatgcata gaggttacac cccagagcaa aatagcatgg atttccgaaa      600

ctctttgtat tggttgtggt atctgtatta agaaatgccc ctttggcgcc ttatcaattg      660

tcaatctacc aagcaacttg gaaaaagaaa ccacacatcg atattgtgcc aatgccttca      720

aacttcacag gttgcctatc cctcgtccag gtgaagtttt gggattagtt ggaactaatg      780

gtattggaaa gtcaactgct ttaaaaattt tagcaggaaa acaaaagcca aaccttggaa      840

agtacgatga tcctcctgac tggcaggaga ttttgactta tttccgtgga tctgaattac      900

aaaattactt tacaaagatt ctagaagatg acctaaaagc catcatcaaa cctcaatatg      960

tagaccagat tcctaaggct gcaaagggga cagtgggatc tattttggac cgaaaagatg     1020

aaacaaagac acaggcaatt gtatgtcagc agcttgattt aacccaccta aaagaacgaa     1080

atgttgaaga tctttcagga ggagagttgc agagatttgc ttgtgctgtc gtttgcatac     1140

agaaagctga tattttcatg tttgatgagc cttctagtta cctagatgtc aagcagcgtt     1200

taaaggctgc tattactata cgatctctaa taaatccaga tagatatatc attgtggtgg     1260

aacatgatct aagtgtatta gactatctct ccgacttcat ctgctgttta tatggtgtac     1320

caagcgccta tggagttgtc actatgcctt ttagtgtaag agaaggcata aacatttttt     1380

tggatggcta tgttccaaca gaaaacttga gattcagaga tgcatcactt gtttttaaag     1440

tggctgagac agcaaatgaa gaagaagtta aaaagatgtg tatgtataaa tatccaggaa     1500

tgaagaaaaa aatgggagaa tttgagctag caattgtagc tggagagttt acagattctg     1560

aaattatggt gatgctgggg gaaaatggaa cgggtaaaac gacatttatc agaatgcttg     1620

ctggaagact taaacctgat gaaggaggag aagtaccagt tctaaatgtc agttataagc     1680

cacagaaaat tagtcccaaa tcaactggaa gtgttcgcca gttactacat gaaaagataa     1740

gagatgctta tactcaccca caatttgtga ccgatgtaat gaagcctctg caaattgaaa     1800

acatcattga tcaagaggtg cagacattat ctggtggtga actacagcga gtagctttag     1860

ccctttgctt gggcaaacct gctgatgtct atttaattga tgaaccatct gcatatttgg     1920

attctgagca aagactgatg gcagctcgag ttgtcaaacg tttcatactc catgcaaaaa     1980

agacagcctt tgttgtggaa catgacttca tcatggccac ctatctagcg gatcgcgtca     2040

tcgtttttga tggtgttcca tctaagaaca cagttgcaaa cagtcctcaa acccttttgg     2100

ctggcatgaa taaatttttg tctcagcttg aaattacatt cagaagagat ccaaacaact     2160

ataggccacg aataaacaaa cttaattcaa ttaaggatgt agaacaaaag aagagtggaa     2220

actacttttt cttggatgat tagactgact ctgagaatat tgataagcca tttattaaaa     2280

ggagtattta ctagaatttt ttgtcatata aaacttgaat caggatttta tgccccacat     2340

actctggaac ttgaagtata atatacttaa tataacataa aaagccagtt gggttctaaa     2400

ttgtagttga aacacagaaa atgccacttt tctgttcctg aagaggctct tttgtgcata     2460

atattctaaa atgaagacat ttcaagctat acaaattact tccaagtttt catgatgtat     2520

gggaagattt tcagtaggtg tattatattc acggtaccaa atgctgacca gtgttgctcc     2580

attttttaaa tcttgaaaag ggtttctgta cttacctggt ttgccaagta tgccagtgta     2640

atgaaactgc ccttatttta aaagccagtc aaagattcca ctgattgaca tttgataaat     2700

aaacatcagg attatgttta ttgtttgttt tcagtctttg cactatatta ccagtatatg     2760

gtttccgagg aagattatct actgcaaaac accactgttg gaaaaatagg tatttttaaa     2820

ttgtttttaa tcttttttgg tgcttttaaa catgtttagc aaaaaccaat tcagttccat     2880

tccccgcaaa aaacccctaa ctttactctg aacttttttt gtttttgcat tccatgaggt     2940

tctgtattca gtcattctct aggtaatgtc atttttgtac acatatattt atataatcac     3000

tgattgagat ttaggaaaaa gcatttctaa agaatatttg cttcccttag aactacagac     3060

tcgaaatctt taaagatggt gcctaagcat ctatgtattt tttttaagtt ccacagattt     3120

ttctgttggg cagccaagga ttataaacca cttccctaaa ggcaacatta atgcaaaagt     3180

ccccagatgg caatacaaag tatcccctgg taccacatat attcatttgt gagtttggat     3240

atagagcaca ttatctaaac cattttgtag ttccaaaaac ccatctaaat ttcttgagtt     3300

cctgaatttt gaacaggatt acctggagcc tggagccact ttaagttgta cttctgacta     3360

aactggaatt atgagtgagg aagagtgttt actaaataaa tgactggggc aagcaaaatt     3420

gaggaggaaa ttagaaactg tttgacaaac tttaagagct acttgaaata acagaagtct     3480

tgattaatat gcaaataatg gctagaaagt atggtttaac tggaccctat tatgcctttt     3540

aaaaataatt tcagtaaccc ataaatacat gttgtaaaaa attcaaatat acagaatgga     3600

ataaaaaaat gatctccctt tattaccctc ccaaaggtta ccagcgtttg aatttaataa     3660

tgtatattct ttcatgcttt tttctgtgca cttacctaag tgtgaatatg taaagggttt     3720

gttttgtata caaatgggat tatactaaaa taagtaatgc ctatttttaa ggataggtta     3780

aatttgtgaa tgatcatttc aaatatattg aataaaataa gcaaaagcta ttgttattta     3840

ctgatcctgg attgtcttaa agaaagtact tgtgatataa gagcacagtt ctacttactg     3900

ctaatgacag aatatgtatt aaacgtattt tcatgtaaat gaaatcttta aaatatgtat     3960

cttaaaattt tacatagcaa cagaaaggcc tacaattgct aacacaagaa aaatacttat     4020

aaaatcagta taaaatcaat gcagatgtta gcaaaagaat gagactactt catatgtcct     4080

aattggaaaa agtctcaaat acttaaaaaa acaaaaaact ggaacagttt attatactac     4140

catttttgtg aaaatataca aaatattgaa ataaaggaat actcaagaaa caga           4194


<210>  2677
<211>  2965
<212>  DNA
<213>  homo sapiens

<400>  2677
aaagcaggcc tgtcccttta agggggttgg ctgtcaatca gaaagccctt ttcattgcag       60

gagaagagga caaagatact cagagagaaa aagtaaaaga ccgaagaagg aggctggaga      120

gaccaggatc cttccagctg aacaaagtca gccacaaagc agactagcca gccggctaca      180

attggagtca gagtcccaaa gacatgggct tgttagagtg ctgtgcaaga tgtctggtag      240

gggccccctt tgcttccctg gtggccactg gattgtgttt ctttggggtg gcactgttct      300

gtggctgtgg acatgaagcc ctcactggca cagaaaagct aattgagacc tatttctcca      360

aaaactacca agactatgag tatctcatca atgtgatcca tgccttccag tatgtcatct      420

atggaactgc ctctttcttc ttcctttatg gggccctcct gctggctgag ggcttctaca      480

ccaccggcgc agtcaggcag atctttggcg actacaagac caccatctgc ggcaagggcc      540

tgagcgcaac gtttgtgggc atcacctatg ccctgaccgt tgtgtggctc ctggtgtttg      600

cctgctctgc tgtgcctgtg tacatttact tcaacacctg gaccacctgc cagtctattg      660

ccttccccag caagacctct gccagtatag gcagtctctg tgctgatgcc agaatgtatg      720

gtgttctccc atggaatgct ttccctggca aggtttgtgg ctccaacctt ctgtccatct      780

gcaaaacagc tgagttccaa atgaccttcc acctgtttat tgctgcattt gtgggggctg      840

cagctacact ggtttccctg ctcaccttca tgattgctgc cacttacaac tttgccgtcc      900

ttaaactcat gggccgaggc accaagttct gatcccccgt agaaatcccc ctttctctaa      960

tagcgaggct ctaaccacac agcctacaat gctgcgtctc ccatcttaac tctttgcctt     1020

tgccaccaac tggccctctt cttacttgat gagtgtaaca agaaaggaga gtcttgcagt     1080

gattaaggtc tctctttgga ctctcccctc ttatgtacct cttttagtca ttttgcttca     1140

tagctggttc ctgctagaaa tgggaaatgc ctaagaagat gacttcccaa ctgcaagtca     1200

caaaggaatg gaggctctaa ttgaattttc aagcatctcc tgaggatcag aaagtaattt     1260

cttctcaaag ggtacttcca ctgatggaaa caaagtggaa ggaaagatgc tcaggtacag     1320

agaaggaatg tctttggtcc tcttgccatc tataggggcc aaatatattc tctttggtgt     1380

acaaaatgga attcattctg gtctctctat taccactgaa gatagaagaa aaaagaatgt     1440

cagaaaaaca ataagagcgt ttgcccaaat ctgcctattg cagctgggag aagggggtca     1500

aagcaaggat ctttcaccca cagaaagaga gcactgaccc cgatggcgat ggactactga     1560

agccctaact cagccaacct tacttacagc ataagggagc gtagaatctg tgtagacgaa     1620

gggggcatct ggccttacac ctcgttaggg aagagaaaca gggtgttgtc agcatcttct     1680

cactcccttc tccttgataa cagctaccat gacaaccctg tggtttccaa ggagctgaga     1740

atagaaggaa actagcttac atgagaacag actggcctga ggagcagcag ttgctggtgg     1800

ctaatggtgt aacctgagat ggccctctgg tagacacagg atagataact ctttggatag     1860

catgtctttt tttctgttaa ttagttgtgt actctggcct ctgtcatatc ttcacaatgg     1920

tgctcatttc atggggtatt atccattcag tcatcgtagg tgatttgaag gtcttgattt     1980

gttttagaat gatgcacatt tcatgtattc cagtttgttt attacttatt tggggttgca     2040

tcagaaatgt ctggagaata attctttgat tatgactgtt ttttaaacta ggaaaattgg     2100

acattaagca tcacaaatga tattaaaaat tggctagttg aatctattgg gattttctac     2160

aagtattctg cctttgcaga aacagatttg gtgaatttga atctcaattt gagtaatctg     2220

atcgttcttt ctagctaatg gaaaatgatt ttacttagca atgttatctt ggtgtgttaa     2280

gagttaggtt taacataaag gttattttct cctgatatag atcacataac agaatgcacc     2340

agtcatcagc tattcagttg gtaagcttcc aggaaaaagg acaggcagaa agagtttgag     2400

acctgaatag ctcccagatt tcagtctttt cctgtttttg ttaactttgg gttaaaaaaa     2460

aaaaaagtct gattggtttt aattgaagga aagatttgta ctacagttct tttgttgtaa     2520

agagttgtgt tgttcttttc ccccaaagtg gtttcagcaa tatttaagga gatgtaagag     2580

ctttacaaaa agacacttga tacttgtttt caaaccagta tacaagataa gcttccaggc     2640

tgcatagaag gaggagaggg aaaatgtttt gtaagaaacc aatcaagata aaggacagtg     2700

aagtaatccg taccttgtgt tttgttttga tttaataaca taacaaataa ccaacccttc     2760

cctgaaaacc tcacatgcat acatacacat atatacacac acaaagagag ttaatcaact     2820

gaaagtgttt ccttcatttc tgatatagaa ttgcaatttt aacacacata aaggataaac     2880

ttttagaaac ttatcttaca aagtgtattt tataaaatta aagaaaataa aattaagaat     2940

gttctcaatc aaaaaaaaaa aaaaa                                           2965


<210>  2678
<211>  8934
<212>  DNA
<213>  homo sapiens

<400>  2678
agtctgtcac acagggacat caccctacag cagttcaggc tgtgtggttc gcaggaagca       60

tacactggct ttttgattct tgctagttcc cagctcacag tttgggagga tccaacacca      120

acctttacgt gaagtggagg cccaaggaca gtgaggagct gggtggtccc agcctggagc      180

tgtgccagcc tgacatggaa atggaggcaa acgaccattt taactttact ggccttcccc      240

ctgcacctgc tgcctcagga ctgaaaccct ctccttcctc aggggagggc ctctacacta      300

acgggtctcc catgaacttc ccccagcaag ggaaaagttt gaatggggat gtgaatgtta      360

atggcttatc tactgtatct cacactacta cttcagggat tttgaactct gctccccact      420

cctccagcac ctcacacctc catcacccca gcgtggccta cgactgtctc tggaactact      480

cacagtaccc atctgccaat cctggcagca acctcaagga cccacccctt ctctcccagt      540

tctcgggggg acaataccca ctcaacggca tccttggggg cagccggcaa ccttcatccc      600

caagtcataa cactaacctt cgggctggga gccaagagtt ctgggccaac ggtacccaga      660

gtcccatggg gcttaacttt gattcacaag aactgtatga ttcctttcct gaccagaatt      720

ttgaggtgat gcccaatgga ccccctagtt ttttcacctc cccacagact tctcctatgt      780

tgggatctag cattcaaacc tttgcaccct cccaggaggt aggcagtggt atccatcctg      840

atgaggcagc agaaaaggag atgacttcag ttgtggcaga gaatggcact ggcttggtag      900

gcagcttgga gctggaagaa gagcagccag aactgaagat gtgtggctac aatggctctg      960

tcccttctgt ggaatcgtta caccaagagg tctcagtcct ggtccctgac cccacagtga     1020

gctgtttaga tgatccttca catcttcctg atcaactgga agacactcca atcctcagtg     1080

aagactctct ggagcccttc aactctctgg caccagagcc agtgagtgga ggactatatg     1140

gtattgatga cacggagctg atgggtgcag aggacaagct gcctcttgag gacagccctg     1200

tgatttctgc ccttgattgc ccttccctca ataatgctac tgccttcagt ctcctggcag     1260

atgatagtca aacatcaacc tctatctttg ccagtcccac ctctccacct gtcctagggg     1320

agtctgtcct gcaagataac agctttgacc tgaataatgg tagtgacgct gaacaggaag     1380

aaatggaaac tcaatcttca gacttcccac catccctgac ccagccagct cctgatcagt     1440

catccactat tcagctacat ccagcaacct caccagcagt ctcgccaaca acctccccag     1500

cagtctccct agtggtttct ccagcagcct ccccagaaat ctctccagaa gtttgtcccg     1560

cagcttctac agttgtctct ccagcagtct tctcagtggt ctctccagct tcctcagcag     1620

tcctcccagc agtctcctta gaagtcccgt tgacggcttc agtgacatcc ccaaaagcct     1680

ctcccgtaac ttccccagca gctgcctttc caacagcctc cccagcaaat aaggatgtca     1740

gcagctttct agaaaccact gctgacgtgg aagagatcac tggagaagga ctcactgctt     1800

ctggtagtgg tgatgtcatg aggagacgta ttgctacccc agaagaagtt cgtcttcccc     1860

tccaacatgg gtggcggaga gaggtgcgca tcaagaaggg cagccaccga tggcaggggg     1920

agacctggta ttatggcccc tgtgggaaga ggatgaagca atttccagaa gtgatcaagt     1980

acctgagccg caacgtggta cacagtgtcc gccgagagca cttcagcttc agtccccgta     2040

tgcctgttgg agatttcttt gaagaaagag acacgccaga gggcttgcag tgggtgcagc     2100

tctcagcaga ggagatcccg tcgaggattc aggcaattac tggcaaacgg ggtcgacctc     2160

gaaacactga gaaggctaag actaaggaag tccccaaggt gaaacggggt cgaggtcggc     2220

cacctaaggt caaaatcact gagctattga acaagacaga caaccgcccc ctaaagaaac     2280

tggaggccca agaaacattg aatgaggagg ataaagcaaa gattgctaaa agcaagaaga     2340

agatgaggca gaaggttcaa cggggagagt gtcagactac tatccaaggg caggccagaa     2400

ataagcggaa acaagagacc aagagcttaa agcagaagga agctaagaag aaatccaagg     2460

ctgagaaaga aaaaggaaag acaaagcagg aaaaactgaa ggaaaaagtc aagagggaaa     2520

agaaggagaa ggtaaaaatg aaggaaaagg aggaggtgac caaagccaag ccagcctgta     2580

aagcagataa gaccctggcc acacagaggc gcttggagga acggcagagg cagcagatga     2640

tcttggagga aatgaagaag ccgacagagg atatgtgtct gactgaccac cagcccctgc     2700

ctgacttctc acgagtccct ggtctgacat tgcccagtgg agccttctca gactgcttga     2760

ccattgtgga gttcctgcat agctttggca aggtgctggg ctttgatcct gccaaagatg     2820

tgcctagcct gggggtcctg caggagggac tcctgtgtca aggtgacagc ttgggtgagg     2880

tgcaagacct gctggtcagg ctgctgaagg ctgcactcca tgatcctggc tttccctcct     2940

actgtcagtc cctaaagatc ttgggggaga aggtgtctga gatcccactg acaagagaca     3000

atgtgtcaga gatcctgcgc tgcttcctta tggcatatgg agtagagcca gccctctgtg     3060

accgcctgcg cacccagcct tttcaggccc agccacccca gcagaaggct gctgtcctgg     3120

ccttccttgt gcatgagctc aatggctcca ccctcatcat caatgagatt gacaagactc     3180

tggagagtat gtccagctac aggaaaaaca agtggattgt tgaaggccgg ctccggaggc     3240

tgaaaactgt tctggccaag cgaactgggc ggtctgaagt agagatggaa gggccagagg     3300

aatgcctggg acggaggcgc agttctcgga tcatggagga gaccagtggc atggaagaag     3360

aggaagaaga ggagtctata gcagctgtcc ctggccgcag gggtcgaaga gatggagagg     3420

ttgatgccac agcatctagc atcccagagc tagagcgcca gatagaaaaa ctcagcaagc     3480

gtcagctttt ctttcgcaaa aagctgcttc actcatccca gatgcttcgg gcggtctccc     3540

tgggtcagga ccgctacaga cgtcgctact gggtattgcc gtatttggct ggtatctttg     3600

tagaaggaac agaggggaac ttagttcctg aggaggtgat aaagaaggaa actgactcct     3660

taaaagtggc agcccatgcg tcactcaacc ctgccctctt ctctatgaag atggagttag     3720

ctggctccaa caccactgcc agttctcctg cccgggcccg aggccgacct cgaaaaacta     3780

agcccgggtc tatgcaacct aggcatctta agtcccctgt caggggtcag gattcagaac     3840

agccccaggc ccagcttcag cctgaggctc agcttcatgc tcctgcccag ccccagcctc     3900

agcttcagct tcagcttcag tcccataagg ggttcctgga gcaagaaggc tcccctttgt     3960

cactgggtca gagccagcat gacctcagcc agtcagcctt cctgtcttgg ctgagccaga     4020

ctcagagcca tagctccctg ttgagcagct cagtcctcac acctgatagc agtccgggaa     4080

aactagaccc agctccatca caacccccgg aggagccaga gcctgatgag gcagaatcca     4140

gccctgatcc tcaagcactc tggtttaaca tctcagccca gatgccctgc aatgctgccc     4200

ccacaccgcc ccctgcagtt tctgaggacc aacccactcc ctcccctcag cagcttgcct     4260

cctccaagcc aatgaataga cctagtgctg ccaacccttg ttctccagtg cagttctctt     4320

ccacgccctt ggctgggttg gcccctaaga ggcgagcagg agaccctgga gaaatgccac     4380

agagtcccac agggctggga cagcccaaac ggagagggag acctcccagt aagttcttca     4440

aacagatgga acagcgttac ctaacccagc tgacagccca gcctgtccca cctgagatgt     4500

gctcaggctg gtggtggata cgagatcctg agatgttgga tgccatgctc aaggccctac     4560

acccccgagg tatccgggag aaggcacttc acaaacacct taacaagcac agggacttct     4620

tgcaggaagt ctgcctgcgg ccctcagctg accccatctt tgagcccagg caactacctg     4680

cctttcaaga agggattatg agctggtccc ccaaagagaa gacatacgag acagacctag     4740

cagtgcttca atgggtagag gagctggagc agcgggttat catgtctgat ctgcagattc     4800

ggggctggac atgtcctagc ccagactcta cccgtgaaga cttggcctac tgtgagcacc     4860

tctccgactc ccaggaggat atcacctggc gaggtcgggg cagggaggga ctggcacctc     4920

agcgtaaaac taccaaccct ttggacctgg ctgtgatgcg gctggctgcc ctggaacaga     4980

atgtagaacg gcggtacctg cgggagcccc tctggccaac tcatgaggtt gtgctggaga     5040

aggccctgct tagcacacct aatggtgccc ctgagggcac cactacagag atatcatatg     5100

agatcacccc tcgcattcgt gtctggcgcc agaccctcga gcggtgccgg agcgcagccc     5160

aggtgtgctt gtgcctgggc cagctggaga ggtccattgc ctgggagaag tctgtcaaca     5220

aagtgacatg tctagtctgc cggaagggtg acaatgatga gtttcttctg ctttgtgatg     5280

ggtgtgaccg tggctgccac atttactgcc atcgtcccaa gatggaggct gtcccagaag     5340

gagattggtt ctgtactgtc tgtttggctc agcaggtgga gggagaattc actcagaagc     5400

ctggtttccc aaagcgtggc cagaagcgga aaagtggtta ttcgctgaac ttctcagagg     5460

gtgatggccg ccgacgccgg gtactgttga ggggccgaga aagcccagca gcagggcctc     5520

ggtactcgga agaagggctc tccccctcca agcggcggcg actctctatg cggaaccacc     5580

acagtgatct cacattttgc gagattatcc tgatggagat ggagtcccat gatgcagcct     5640

ggcctttcct agagcctgtg aacccacgtt tggtgagtgg gtaccggcgc atcatcaaaa     5700

atcctatgga tttttccacc atgcgggagc ggctgctcag gggagggtac accagctcag     5760

aggagtttgc ggctgatgcc ctcctggtat ttgacaactg ccagactttc aacgaggatg     5820

actctgaagt aggcaaggct gggcacatca tgcgccgctt cttcgagagc cgctgggagg     5880

agttttatca gggaaaacag gccaatctgt gaggcaaggg aggtggggag tcaccttgtg     5940

gcatctcccc ccaccttcca aacaaaaacc tgccattttc acctgctgat gctgccctgg     6000

gtccagactc aagtcagata caaccctgat ttttgacctt gcccttggca gtgccccaca     6060

tcctcttatt cctacatccc tttctccctt ccctcctctt gctcctcaag taagaggtgc     6120

agagatgagg tccttctgga ctaaaagcca aaaaaagaaa gaaaaaaata atttttcttt     6180

tctgttttat ttgctaatta aaaatgggga gggggaaagt cgtccctact tcctcctccc     6240

tgcttcctct cctcccctgt acgtgcccca gcattctggg gttatttaac aatagcaata     6300

gttctagtga atgtgtgaaa ccaagaaaca ctctgtactg tgtgcggacc cgcagtgacg     6360

gccagtaaag tggacttaac tcccaagtgt gtcgcgccgg acaccgggcc ctggacatgc     6420

tgcttccatg ttcagtccct tccctgcttc tcgctgtctt tcttttccca cctcccaccc     6480

cccagttttc agattttctc tcatccaata atgtaaaact atcgtgtacg ggttcctccc     6540

tccttttctc ttctcccaaa tcttttccct tcaaaggaaa aaaaaatgtt cagaggtccc     6600

tgtcttctgt ccccatcttc ctgccgatag ctatcccctg tatgatgttg gatgctcctc     6660

acatgctgag tttccagcct tttctgaaac tcagtagctg gggagagggc agggaggctt     6720

cctgggcctt ccagcctcct tccccacctc cttcccaaac cctcttggga actcctcagg     6780

gacaactact gctgagtttg ggtgcaccct aagatggagg ccaggtagca atggggccgg     6840

cctcagagag agcgctgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtcggcctca     6900

gagcgcgctg tgtgtgtgtg tgtgtgtgtc agcctcagag cgcgcgctgt gtgtgtgtgt     6960

gtgtgtgcgt gcttgtgacc ctgtattgtt tgataggatc cattcagttt ccccaagtac     7020

ctgttttcat tcccattttt cccattgttt aaaaccatca cttttttgtc tttgggaaac     7080

cacaggaaca atttctctgg agacaaggct gtgtctctct cctggtcatt tttgttccag     7140

cctcttcaga ctgtgcaatc tttcagcagg aactccctct cttctcggta gctttgaatc     7200

ttaagcttct acgggagagt ggtagaactg gatcatttcc taatcccatt tagttgtgct     7260

tttcttcatt tacttcatac cccaggaccc cttccccagc agcagagacc ctggagcaca     7320

ggagagtagg gaggaggggt tctgggtcca tcactgccct acatgtgact atgtccaagt     7380

taagccccca acacgagagg aaagctgctg actcccagct atagccatgg gcacttggcc     7440

ccctgctttt cctgctcagc agagcccctc ccttcagaga ttacgggtac ttgcactggg     7500

gaggtggctg ctggctggcc caagcagaga gctgaggcat ccaagaaatg ttccattggg     7560

gggtgggggt gccaggtgag gtggagcatt ccttgtattc tggcagcact gaagagccac     7620

tgaagggggt aggggcagtg taggtcctgg ggcagcccct ttattccttt atgccccttc     7680

tccctcatag cctatttcta aagtcgcctt ttctgtcaga taaacctcaa aacttttaat     7740

tttatttgag attttttttt gcttttaaga ggtggattga agaatatttg aattgacttt     7800

atattatgca taaatattta tattttatct aaataactgc gctgtaacaa actttgtgtt     7860

agacagttga aactgttaga gttgggggct ctgctttttc cccctggcaa ttttcccctg     7920

gtataagatg tgctagatta atttcattgt gaggtggatg ggggagtgaa attgtgaggt     7980

ggatggggga gtgaaatctc catggttcct gctttgtgtt cctctcccag ctccatctct     8040

ttccctaggg accaggcact catatggcgg ggtggggtcc tagcctcagt ttgaagaagt     8100

gggggctgga gcggggttgg gggtggtagg gatagggcat gatcaaaggg gccatttctt     8160

gcttttcttt cctcatcttc actgccccct tgagctaggt ggattttctc ttcatgacaa     8220

gagtatttgg tagggaaagc aggtttaaaa taaaaagaca acccaccccc tgcccttttg     8280

cttccctccc atcagtctgg ttgacaggaa gaaaccacac catcaacacc aacaagtttc     8340

tgtgttcctt ttacagcaaa agggactttt tatataacca aatgtggtgt tttagtgact     8400

ttttgataat gtacagtttt ttgtgaattt aaatttattt ctttctatat ttttaggacc     8460

aatctcattt ttaataaggt taaaaagaaa aaaaaagtct agcgaaaaaa ctcctgtttt     8520

tgccatgtga tgttccacaa gtgcagctgt agaaaagtgc ttgtcagttg ttgaataaaa     8580

aaaaccacat ttgatagaga ttcaaaagac tctgtgtatt catcttccct tctacacacc     8640

tgagggggag acggcgttgg gataggtatg actggcttaa gagaccacag gcaagggaac     8700

aacaggggct cctgttccat accctctgtg tggatggaaa gggtcattag tgctcctgcc     8760

taaatgtctg gctgagttgc tggagcaaag ggggattcag tgcatccagg tcctgccttg     8820

tgagatgtgg ccccagcttc ctaagctgcc acctctgtgt tcctgtcata gcaaatatgg     8880

gaccatcacc agcttaccac ttcccactca cggataagac accaagacgt agac           8934


<210>  2679
<211>  2814
<212>  DNA
<213>  homo sapiens

<400>  2679
cacagaaggc gccgaggctc caccgcgcag ccgcaaaaag agcggacggg tctgcgccgc       60

cgcaggagga gcaggcggta cctggacggg ttcgtcccgg gctgtttcgc gtccggcctg      120

aggcggctgg ggccgcgcag gtagtgtccc tgcacttctt gcccgggcgc gtgaggccag      180

ctccgctgcg cttgtctcca gcttccagcc ctcctcccct aagccgccgc catcatgctg      240

ctgcctgtgt tcaccctgaa actgcgccac aaaatcagcc cccgaatggt ggccataggg      300

cgctacgacg ggactcaccc gtgcctggcg gccgccaccc aaacgggcaa ggtttttatt      360

cataatcctc atacacggaa ccagcatgtc agtgcatcca gggtcttcca gagccccctg      420

gaatctgatg tttctcttct caacattaac caggcagtca gctgtctgac tgcaggcgta      480

ttgaaccctg agcttggcta tgatgccctt ttagtgggga cacagactaa tcttttggct      540

tatgatgtct acaataattc ggatttgttc tacagagagg tagcagatgg ggcaaatgca      600

attgtgctgg ggacattggg agacatttct tcccctcttg cgattattgg tggcaattgt      660

gctctgcaag gtttcaatca tgaaggaagt gatctctttt ggacggttac tggagacaat      720

gttaattcct tggccttgtg tgactttgat ggtgatggaa agaaagagct tcttgttgga      780

tctgaggatt ttgatatccg agtttttaag gaagatgaga ttgtggcaga aatgacagaa      840

acagagatag tcacctctct ttgtcccatg tatggcagtc gatttggtta tgccctttcc      900

aatggcacag ttggagttta tgacaaaaca tcccgatact ggagaattaa atcgaaaaat      960

catgccatga gcattcatgc ttttgacctt aattctgatg gagtgaatga actgataact     1020

ggttggtcca atgggaaggt tgatgctcga agtgaccgaa ctggggaggt catctttaag     1080

gacaattttt cttctgcaat tgccggtgtg gtagagggag attaccggat ggatggccac     1140

atacagttaa tctgctgctc agtggatggg gaaatccggg gctacctgcc tggcacggct     1200

gagatgaggg gcaacctcat ggacaccagt gcagagcagg acctgatccg agagctgagt     1260

cagaagaagc agaatctgtt gctggaactc cgtaactatg aggaaaatgc caaggctgaa     1320

ttggccagtc cactgaacga ggctgatggg catcggggca taatcccagc caataccagg     1380

ctccacacca cgctctcagt cagcctgggg aatgagaccc aaactgctca tacagaatta     1440

cgcatttcca cttctaatga caccatcatc cgagcagtat tgatttttgc agaaggaatt     1500

tttacaggtg aaagccacgt ggtacatccc agcattcaca acctctccag ttccatctgc     1560

atccctattg tgcctcccaa agatgtccct gtggatctgc acttgaaggc attcgtgggt     1620

tacagaagca gcacccagtt tcatgtattt gaatcgacaa gacagctccc tcgattctcc     1680

atgtatgcgc tgaccagcct ggaccctgcc agtgagccaa tcagttatgt taactttacc     1740

attgcagaac gggcacagag ggttgttgta tggctcggtc agaactttct gttaccagaa     1800

gacactcaca ttcagaatgc tccatttcaa gtgtgtttca catctttacg gaatggcggc     1860

cacctgcata taaaaataaa acttagtgga gagatcacta taaatactga tgatattgat     1920

ttggctggtg atatcatcca gtcaatggca tcattttttg ctattgaaga ccttcaagta     1980

gaagcggatt ttcctgtcta ttttgaggaa ttacgaaagg tgctagttaa ggtggatgaa     2040

tatcattcag tgcatcagaa gctcagtgct gatatggctg atcattctaa tttgatccga     2100

agtttgctgg tcggagctga ggatgctcgt ctgatgaggg acatgaaaac aatgaagagt     2160

cgttatatgg aactctatga ccttaataga gacttgctaa atggatataa aattcgctgt     2220

aacaatcaca cagagctgtt gggaaacctc aaagcagtaa atcaagcaat tcaaagagca     2280

ggtcgtctgc gggttggaaa accaaagaac caggtgatca ctgcttgtcg ggatgcaatt     2340

cgaagcaata acatcaacac actgttcaaa atcatgcgag tggggacagc ttcttcctag     2400

gtgaggaaaa tacaggtcat gaagttcctg gcaaagattt tctgttaaaa acctatgctg     2460

gtttgctttg gatcacaccc tggtgaaccc cgggtgctaa gaatgaaaat aaccttggtg     2520

agttgtacaa attaaagaca aagaactaca tgtgaagata gacttgcttt ctatttttaa     2580

atcagtagta gtactgttgc tgaataatac taggttttta tggaatagga tgaatgcttt     2640

tgaagtatta gggcttcaga gtccaatttt gcttatttat ggtatataaa tacatatttt     2700

tttcttgaaa ttgcaattga gtttgtactt ttcaaataga ttatctactt tttcattaaa     2760

atgtaaagat gttaaacttt gtgttgattg attataaaat caccaccaaa tcag           2814


<210>  2680
<211>  2814
<212>  DNA
<213>  homo sapiens

<400>  2680
cacagaaggc gccgaggctc caccgcgcag ccgcaaaaag agcggacggg tctgcgccgc       60

cgcaggagga gcaggcggta cctggacggg ttcgtcccgg gctgtttcgc gtccggcctg      120

aggcggctgg ggccgcgcag gtagtgtccc tgcacttctt gcccgggcgc gtgaggccag      180

ctccgctgcg cttgtctcca gcttccagcc ctcctcccct aagccgccgc catcatgctg      240

ctgcctgtgt tcaccctgaa actgcgccac aaaatcagcc cccgaatggt ggccataggg      300

cgctacgacg ggactcaccc gtgcctggcg gccgccaccc aaacgggcaa ggtttttatt      360

cataatcctc atacacggaa ccagcatgtc agtgcatcca gggtcttcca gagccccctg      420

gaatctgatg tttctcttct caacattaac caggcagtca gctgtctgac tgcaggcgta      480

ttgaaccctg agcttggcta tgatgccctt ttagtgggga cacagactaa tcttttggct      540

tatgatgtct acaataattc ggatttgttc tacagagagg tagcagatgg ggcaaatgca      600

attgtgctgg ggacattggg agacatttct tcccctcttg cgattattgg tggcaattgt      660

gctctgcaag gtttcaatca tgaaggaagt gatctctttt ggacggttac tggagacaat      720

gttaattcct tggccttgtg tgactttgat ggtgatggaa agaaagagct tcttgttgga      780

tctgaggatt ttgatatccg agtttttaag gaagatgaga ttgtggcaga aatgacagaa      840

acagagatag tcacctctct ttgtcccatg tatggcagtc gatttggtta tgccctttcc      900

aatggcacag ttggagttta tgacaaaaca tcccgatact ggagaattaa atcgaaaaat      960

catgccatga gcattcatgc ttttgacctt aattctgatg gagtgaatga actgataact     1020

ggttggtcca atgggaaggt tgatgctcga agtgaccgaa ctggggaggt catctttaag     1080

gacaattttt cttctgcaat tgccggtgtg gtagagggag attaccggat ggatggccac     1140

atacagttaa tctgctgctc agtggatggg gaaatccggg gctacctgcc tggcacggct     1200

gagatgaggg gcaacctcat ggacaccagt gcagagcagg acctgatccg agagctgagt     1260

cagaagaagc agaatctgtt gctggaactc cgtaactatg aggaaaatgc caaggctgaa     1320

ttggccagtc cactgaacga ggctgatggg catcggggca taatcccagc caataccagg     1380

ctccacacca cgctctcagt cagcctgggg aatgagaccc aaactgctca tacagaatta     1440

cgcatttcca cttctaatga caccatcatc cgagcagtat tgatttttgc agaaggaatt     1500

tttacaggtg aaagccacgt ggtacatccc agcattcaca acctctccag ttccatctgc     1560

atccctattg tgcctcccaa agatgtccct gtggatctgc acttgaaggc attcgtgggt     1620

tacagaagca gcacccagtt tcatgtattt gaatcgacaa gacagctccc tcgattctcc     1680

atgtatgcgc tgaccagcct ggaccctgcc agtgagccaa tcagttatgt taactttacc     1740

attgcagaac gggcacagag ggttgttgta tggctcggtc agaactttct gttaccagaa     1800

gacactcaca ttcagaatgc tccatttcaa gtgtgtttca catctttacg gaatggcggc     1860

cacctgcata taaaaataaa acttagtgga gagatcacta taaatactga tgatattgat     1920

ttggctggtg atatcatcca gtcaatggca tcattttttg ctattgaaga ccttcaagta     1980

gaagcggatt ttcctgtcta ttttgaggaa ttacgaaagg tgctagttaa ggtggatgaa     2040

tatcattcag tgcatcagaa gctcagtgct gatatggctg atcattctaa tttgatccga     2100

agtttgctgg tcggagctga ggatgctcgt ctgatgaggg acatgaaaac aatgaagagt     2160

cgttatatgg aactctatga ccttaataga gacttgctaa atggatataa aattcgctgt     2220

aacaatcaca cagagctgtt gggaaacctc aaagcagtaa atcaagcaat tcaaagagca     2280

ggtcgtctgc gggttggaaa accaaagaac caggtgatca ctgcttgtcg ggatgcaatt     2340

cgaagcaata acatcaacac actgttcaaa atcatgcgag tggggacagc ttcttcctag     2400

gtgaggaaaa tacaggtcat gaagttcctg gcaaagattt tctgttaaaa acctatgctg     2460

gtttgctttg gatcacaccc tggtgaaccc cgggtgctaa gaatgaaaat aaccttggtg     2520

agttgtacaa attaaagaca aagaactaca tgtgaagata gacttgcttt ctatttttaa     2580

atcagtagta gtactgttgc tgaataatac taggttttta tggaatagga tgaatgcttt     2640

tgaagtatta gggcttcaga gtccaatttt gcttatttat ggtatataaa tacatatttt     2700

tttcttgaaa ttgcaattga gtttgtactt ttcaaataga ttatctactt tttcattaaa     2760

atgtaaagat gttaaacttt gtgttgattg attataaaat caccaccaaa tcag           2814


<210>  2681
<211>  4859
<212>  DNA
<213>  homo sapiens

<400>  2681
cggcgtcgcc gcaagagcgc gagaggcgcg gcgggaggag ccggcggcgc gcgcctccct       60

gggcccggac tcggccgcct cccgccgcct cccgcgcggc catggactga gcgccgccgg      120

ccaggccgcg gggatggggc cgccgctccc gctgctgctg ctgctactgc tgctgctgcc      180

gccacgcgtc ctgcctgccg ccccttcgtc cgtcccccgc ggccggcagc tcccggggcg      240

tctgggctgc ctgctcgagg agggcctctg cggagcgtcc gaggcctgtg tgaacgatgg      300

agtgtttgga aggtgccaga aggttccggc aatggacttt taccgctacg aggtgtcgcc      360

cgtggccctg cagcgcctgc gcgtggcgtt gcagaagctt tccggcacag gtttcacgtg      420

gcaggatgac tatactcagt atgtgatgga ccaggaactt gcagacctcc cgaaaaccta      480

cctgaggcgt cctgaagcat ccagcccagc caggccctca aaacacagcg ttggcagcga      540

gaggaggtac agtcgggagg gcggtgctgc cctggccaac gccctccgac gccacctgcc      600

cttcctggag gccctgtccc aggccccagc ctcagacgtg ctcgccagga cccatacggc      660

gcaggacaga ccccccgctg agggtgatga ccgcttctcc gagagcatcc tgacctatgt      720

ggcccacacg tctgcgctga cctaccctcc cgggtcccgg acccagctcc gcgaggacct      780

cctgccgcgg accctcggcc agctccagcc agatgagctc agccctaagg tggacagtgg      840

tgtggacaga caccatctga tggcggccct cagtgcctat gctgcccaga ggcccccagc      900

tccccccggg gagggcagcc tggagccaca gtaccttctg cgtgcaccct caagaatgcc      960

caggcctttg ctggcaccag ccgcccccca gaagtggcct tcacctctgg gagattccga     1020

agacccctcc agcacaggcg atggagcacg gattcatacc ctcctgaagg acctgcagag     1080

gcagccggct gaggtgaggg gcctgagtgg cctggagctg gacggcatgg ctgagctgat     1140

ggctggcctg atgcaaggcg tggaccatgg agtagctcga ggcagccctg ggagagcggc     1200

cctgggagag tctggagaac aggcggatgg ccccaaggcc accctccgtg gagacagctt     1260

tccagatgac ggagtgcagg acgacgatga tagactttac caagaggtcc atcgtctgag     1320

tgccacactc gggggcctcc tgcaggacca cgggtctcga ctcttacctg gagccctccc     1380

ctttgcaagg cccctcgaca tggagaggaa gaagtccgag caccctgagt cttccctgtc     1440

ttcagaagag gagactgccg gagtggagaa cgtcaagagc cagacgtatt ccaaagatct     1500

gctggggcag cagccgcatt cggagcccgg ggccgctgcg tttggggagc tccaaaacca     1560

gatgcctggg ccctcgaagg aggagcagag ccttccagcg ggtgctcagg aggccctcag     1620

cgacggcctg caattggagg tccagccttc cgaggaagag gcgcggggct acatcgtgac     1680

agacagagac cccctgcgcc ccgaggaagg aaggcggctg gtggaggacg tcgcccgcct     1740

cctgcaggtg cccagcagtg cgttcgctga cgtggaggtt ctcggaccag cagtgacctt     1800

caaagtgagc gccaatgtcc aaaacgtgac cactgaggat gtggagaagg ccacagttga     1860

caacaaagac aaactggagg aaacctctgg actgaaaatt cttcaaaccg gagtcgggtc     1920

gaaaagcaaa ctcaagttcc tgcctcctca ggcggagcaa gaagactcca ccaagttcat     1980

cgcgctcacc ctggtctccc tcgcctgcat cctgggcgtc ctcctggcct ctggcctcat     2040

ctactgcctc cgccatagct ctcagcacag gctgaaggag aagctctcgg gactaggggg     2100

cgacccaggt gcagatgcca ctgccgccta ccaggagctg tgccgccagc gtatggccac     2160

gcggccacca gaccgacctg agggcccgca cacgtcacgc atcagcagcg tctcatccca     2220

gttcagcgac gggccgatcc ccagcccctc cgcacgcagc agcgcctcat cctggtccga     2280

ggagcctgtg cagtccaaca tggacatctc caccggccac atgatcctgt cctacatgga     2340

ggaccacctg aagaacaaga accggctgga gaaggagtgg gaagcgctgt gcgcctacca     2400

ggcggagccc aacagctcgt tcgtggccca gagggaggag aacgtgccca agaaccgctc     2460

cctggccgtg ctgacctatg accactcccg ggtcctgctg aaggcggaga acagccacag     2520

ccactcagac tacatcaacg ctagccccat catggatcac gacccgagga accccgcgta     2580

catcgccacc cagggaccgc tgcccgccac cgtggctgac ttttggcaga tggtgtggga     2640

gagcggctgc gtggtgatcg tcatgctgac acccctcgcg gagaacggcg tccggcagtg     2700

ctaccactac tggccggatg aaggctccaa tctctaccac atctatgagg tgaacctggt     2760

ctccgagcac atctggtgtg aggacttcct ggtgaggagc ttctatctga agaacctgca     2820

gaccaacgag acgcgcaccg tgacgcagtt ccacttcctg agttggtatg accgaggagt     2880

cccttcctcc tcaaggtccc tcctggactt ccgcagaaaa gtaaacaagt gctacagggg     2940

ccgttcttgt ccaataattg ttcattgcag tgacggtgca ggccggagcg gcacctacgt     3000

cctgatcgac atggttctca acaagatggc caaaggtgct aaagagattg atatcgcagc     3060

gaccctggag cacttgaggg accagagacc cggcatggtc cagacgaagg agcagtttga     3120

gttcgcgctg acagccgtgg ctgaggaggt gaacgccatc ctcaaggccc ttccccagtg     3180

agcggcagcc tcaggggcct caggggagcc cccaccccac ggatgttgtc aggaatcatg     3240

atctgacttt aattgtgtgt cttctattat aactgcatag taatagggcc cttagctctc     3300

ccgtagtcag cgcagtttag cagttaaaag tgtatttttg tttaatcaaa caataataaa     3360

gagagatttg tggaaaaatc cagttacggg tggaggggaa tcggttcatc aattttcact     3420

tgcttaaaaa aaatactttt tcttaaagca cccgttcacc ttcttggttg aagttgtgtt     3480

aacaatgcag tagccagcac gttcgaggcg gtttccagga agagtgtgct tgtcatctgc     3540

cactttcggg agggtggatc cactgtgcag gagtggccgg ggaagctggc agcactcagt     3600

gaggccgccc ggcacacaag gcacgtttgg catttctctt tgagagagtt tatcattggg     3660

agaagccgcg gggacagaac tgaacgtcct gcagcttcgg ggcaagtgag acaatcacag     3720

ctcctcgctg cgtctccatc aacactgcgc cgggtaccat ggacggcccc gtcagccaca     3780

cctgtcagcc caagcagagt gattcagggg ctccccgggg gcagacacct gtgcacccca     3840

tgagtagtgc ccacttgagg ctggcactcc cctgacctca cctttgcaaa gttacagatg     3900

caccccaaca ttgagatgtg tttttaatgt taaaatattg atttctacgt tatgaaaaca     3960

gatgcccccg tgaatgctta cctgtgagat aaccacaacc aggaagaaca aatctgggca     4020

ttgagcaagc tatgagggtc cccgggagca cacgaaccct gccaggcccc cgctggctcc     4080

tccaggcacg tcccggacct gtggggcccc agagagggga catttccctc ctgggagaga     4140

aggagatcag ggcaactcgg agagggctgc gagcatttcc ctcccgggag aggagatcag     4200

ggcgacctgc acgcactgcg tagagcctgg aagggaagtg agaaaccagc cgaccggccc     4260

tgcccctctt cccgggatca cttaatgaac cacgtgtttt gacatcatgt aaacctaagc     4320

acgtagagat gattcggatt tgacaaaata acatttgagt atccgattcg ccatcacccc     4380

ctaccccaga aataggacaa ttcacttcat tgaccaagat gatcacatgg aaggcggcac     4440

agaggcagct gtgtgggctg cagatttcct gtgtggggtt cagcgtagaa aacgcacctc     4500

catcccgccc ttcccacagc attcctccat cttagataga tggtactctc caaaggccct     4560

accagaggga acacggccta ctgagcggac agaatgatgc caaaatattg cttatgtctc     4620

tacatggtat tgtaatgaat atctgcttta atatagctat catttctttt ccaaaattac     4680

ttctctctat ctggaattta attaatcgaa atgaatttat ctgaatatag gaagcatatg     4740

cctacttgta atttctaact ccttatgttt gaagagaaac ctccggtgtg agatatacaa     4800

atatatttaa ttgtgtcata ttaaacttct gatttcacat tcaaaaaaaa aaaaaaaaa      4859


<210>  2682
<211>  4808
<212>  DNA
<213>  homo sapiens

<400>  2682
cggcgtcgcc gcaagagcgc gagaggcgcg gcgggaggag ccggcggcgc gcgcctccct       60

gggcccggac tcggccgcct cccgccgcct cccgcgcggc catggactga gcgccgccgg      120

ccaggccgcg gggatggggc cgccgctccc gctgctgctg ctgctactgc tgctgctgcc      180

gccacgcgtc ctgcctgccg ccccttcgtc cgtcccccgc ggccggcagc tcccggggcg      240

tctggatgga gtgtttggaa ggtgccagaa ggttccggca atggactttt accgctacga      300

ggtgtcgccc gtggccctgc agcgcctgcg cgtggcgttg cagaagcttt ccggcacagg      360

tttcacgtgg caggatgact atactcagta tgtgatggac caggaacttg cagacctccc      420

gaaaacctac ctgaggcgtc ctgaagcatc cagcccagcc aggccctcaa aacacagcgt      480

tggcagcgag aggaggtaca gtcgggaggg cggtgctgcc ctggccaacg ccctccgacg      540

ccacctgccc ttcctggagg ccctgtccca ggccccagcc tcagacgtgc tcgccaggac      600

ccatacggcg caggacagac cccccgctga gggtgatgac cgcttctccg agagcatcct      660

gacctatgtg gcccacacgt ctgcgctgac ctaccctccc gggtcccgga cccagctccg      720

cgaggacctc ctgccgcgga ccctcggcca gctccagcca gatgagctca gccctaaggt      780

ggacagtggt gtggacagac accatctgat ggcggccctc agtgcctatg ctgcccagag      840

gcccccagct ccccccgggg agggcagcct ggagccacag taccttctgc gtgcaccctc      900

aagaatgccc aggcctttgc tggcaccagc cgccccccag aagtggcctt cacctctggg      960

agattccgaa gacccctcca gcacaggcga tggagcacgg attcataccc tcctgaagga     1020

cctgcagagg cagccggctg aggtgagggg cctgagtggc ctggagctgg acggcatggc     1080

tgagctgatg gctggcctga tgcaaggcgt ggaccatgga gtagctcgag gcagccctgg     1140

gagagcggcc ctgggagagt ctggagaaca ggcggatggc cccaaggcca ccctccgtgg     1200

agacagcttt ccagatgacg gagtgcagga cgacgatgat agactttacc aagaggtcca     1260

tcgtctgagt gccacactcg ggggcctcct gcaggaccac gggtctcgac tcttacctgg     1320

agccctcccc tttgcaaggc ccctcgacat ggagaggaag aagtccgagc accctgagtc     1380

ttccctgtct tcagaagagg agactgccgg agtggagaac gtcaagagcc agacgtattc     1440

caaagatctg ctggggcagc agccgcattc ggagcccggg gccgctgcgt ttggggagct     1500

ccaaaaccag atgcctgggc cctcgaagga ggagcagagc cttccagcgg gtgctcagga     1560

ggccctcagc gacggcctgc aattggaggt ccagccttcc gaggaagagg cgcggggcta     1620

catcgtgaca gacagagacc ccctgcgccc cgaggaagga aggcggctgg tggaggacgt     1680

cgcccgcctc ctgcaggtgc ccagcagtgc gttcgctgac gtggaggttc tcggaccagc     1740

agtgaccttc aaagtgagcg ccaatgtcca aaacgtgacc actgaggatg tggagaaggc     1800

cacagttgac aacaaagaca aactggagga aacctctgga ctgaaaattc ttcaaaccgg     1860

agtcgggtcg aaaagcaaac tcaagttcct gcctcctcag gcggagcaag aagactccac     1920

caagttcatc gcgctcaccc tggtctccct cgcctgcatc ctgggcgtcc tcctggcctc     1980

tggcctcatc tactgcctcc gccatagctc tcagcacagg ctgaaggaga agctctcggg     2040

actagggggc gacccaggtg cagatgccac tgccgcctac caggagctgt gccgccagcg     2100

tatggccacg cggccaccag accgacctga gggcccgcac acgtcacgca tcagcagcgt     2160

ctcatcccag ttcagcgacg ggccgatccc cagcccctcc gcacgcagca gcgcctcatc     2220

ctggtccgag gagcctgtgc agtccaacat ggacatctcc accggccaca tgatcctgtc     2280

ctacatggag gaccacctga agaacaagaa ccggctggag aaggagtggg aagcgctgtg     2340

cgcctaccag gcggagccca acagctcgtt cgtggcccag agggaggaga acgtgcccaa     2400

gaaccgctcc ctggccgtgc tgacctatga ccactcccgg gtcctgctga aggcggagaa     2460

cagccacagc cactcagact acatcaacgc tagccccatc atggatcacg acccgaggaa     2520

ccccgcgtac atcgccaccc agggaccgct gcccgccacc gtggctgact tttggcagat     2580

ggtgtgggag agcggctgcg tggtgatcgt catgctgaca cccctcgcgg agaacggcgt     2640

ccggcagtgc taccactact ggccggatga aggctccaat ctctaccaca tctatgaggt     2700

gaacctggtc tccgagcaca tctggtgtga ggacttcctg gtgaggagct tctatctgaa     2760

gaacctgcag accaacgaga cgcgcaccgt gacgcagttc cacttcctga gttggtatga     2820

ccgaggagtc ccttcctcct caaggtccct cctggacttc cgcagaaaag taaacaagtg     2880

ctacaggggc cgttcttgtc caataattgt tcattgcagt gacggtgcag gccggagcgg     2940

cacctacgtc ctgatcgaca tggttctcaa caagatggcc aaaggtgcta aagagattga     3000

tatcgcagcg accctggagc acttgaggga ccagagaccc ggcatggtcc agacgaagga     3060

gcagtttgag ttcgcgctga cagccgtggc tgaggaggtg aacgccatcc tcaaggccct     3120

tccccagtga gcggcagcct caggggcctc aggggagccc ccaccccacg gatgttgtca     3180

ggaatcatga tctgacttta attgtgtgtc ttctattata actgcatagt aatagggccc     3240

ttagctctcc cgtagtcagc gcagtttagc agttaaaagt gtatttttgt ttaatcaaac     3300

aataataaag agagatttgt ggaaaaatcc agttacgggt ggaggggaat cggttcatca     3360

attttcactt gcttaaaaaa aatacttttt cttaaagcac ccgttcacct tcttggttga     3420

agttgtgtta acaatgcagt agccagcacg ttcgaggcgg tttccaggaa gagtgtgctt     3480

gtcatctgcc actttcggga gggtggatcc actgtgcagg agtggccggg gaagctggca     3540

gcactcagtg aggccgcccg gcacacaagg cacgtttggc atttctcttt gagagagttt     3600

atcattggga gaagccgcgg ggacagaact gaacgtcctg cagcttcggg gcaagtgaga     3660

caatcacagc tcctcgctgc gtctccatca acactgcgcc gggtaccatg gacggccccg     3720

tcagccacac ctgtcagccc aagcagagtg attcaggggc tccccggggg cagacacctg     3780

tgcaccccat gagtagtgcc cacttgaggc tggcactccc ctgacctcac ctttgcaaag     3840

ttacagatgc accccaacat tgagatgtgt ttttaatgtt aaaatattga tttctacgtt     3900

atgaaaacag atgcccccgt gaatgcttac ctgtgagata accacaacca ggaagaacaa     3960

atctgggcat tgagcaagct atgagggtcc ccgggagcac acgaaccctg ccaggccccc     4020

gctggctcct ccaggcacgt cccggacctg tggggcccca gagaggggac atttccctcc     4080

tgggagagaa ggagatcagg gcaactcgga gagggctgcg agcatttccc tcccgggaga     4140

ggagatcagg gcgacctgca cgcactgcgt agagcctgga agggaagtga gaaaccagcc     4200

gaccggccct gcccctcttc ccgggatcac ttaatgaacc acgtgttttg acatcatgta     4260

aacctaagca cgtagagatg attcggattt gacaaaataa catttgagta tccgattcgc     4320

catcaccccc taccccagaa ataggacaat tcacttcatt gaccaagatg atcacatgga     4380

aggcggcaca gaggcagctg tgtgggctgc agatttcctg tgtggggttc agcgtagaaa     4440

acgcacctcc atcccgccct tcccacagca ttcctccatc ttagatagat ggtactctcc     4500

aaaggcccta ccagagggaa cacggcctac tgagcggaca gaatgatgcc aaaatattgc     4560

ttatgtctct acatggtatt gtaatgaata tctgctttaa tatagctatc atttcttttc     4620

caaaattact tctctctatc tggaatttaa ttaatcgaaa tgaatttatc tgaatatagg     4680

aagcatatgc ctacttgtaa tttctaactc cttatgtttg aagagaaacc tccggtgtga     4740

gatatacaaa tatatttaat tgtgtcatat taaacttctg atttcacatt caaaaaaaaa     4800

aaaaaaaa                                                              4808


<210>  2683
<211>  135
<212>  PRT
<213>  homo sapiens

<400>  2683

Met Met Leu Ser Pro Asp Gln Ala Ala Asp Ser Asp His Pro Ser Ser 
1               5                   10                  15      


Ala His Ser Asp Pro Glu Ser Leu Gly Gly Thr Asp Thr Lys Val Leu 
            20                  25                  30          


Gly Ser Val Ser Asp Leu Glu Pro Val Glu Glu Ala Glu Gly Asp Gly 
        35                  40                  45              


Lys Gly Gly Ser Arg Ala Ala Leu Tyr Pro His Pro Gln Gln Leu Ser 
    50                  55                  60                  


Arg Glu Glu Lys Arg Arg Arg Arg Arg Ala Thr Ala Lys Tyr Arg Ser 
65                  70                  75                  80  


Ala His Ala Thr Arg Glu Arg Ile Arg Val Glu Ala Phe Asn Leu Ala 
                85                  90                  95      


Phe Ala Glu Leu Arg Lys Leu Leu Pro Thr Leu Pro Pro Asp Lys Lys 
            100                 105                 110         


Leu Ser Lys Ile Glu Ile Leu Arg Leu Ala Ile Cys Tyr Ile Ser Tyr 
        115                 120                 125             


Leu Asn His Val Leu Asp Val 
    130                 135 


<210>  2684
<211>  801
<212>  PRT
<213>  homo sapiens

<400>  2684

Met Lys Glu Lys Ala Met Ile Lys Thr Ala Lys Met Gln Gly Asn Val 
1               5                   10                  15      


Met Glu Leu Val Gly Ser Asn Pro Pro Gln Arg Asn Trp Lys Gly Ile 
            20                  25                  30          


Ala Ile Ala Leu Leu Val Ile Leu Val Ile Cys Ser Leu Ile Val Thr 
        35                  40                  45              


Ser Val Ile Leu Leu Thr Pro Ala Glu Asp Asn Ser Leu Ser Gln Lys 
    50                  55                  60                  


Lys Lys Val Thr Val Glu Asp Leu Phe Ser Glu Asp Phe Lys Ile His 
65                  70                  75                  80  


Asp Pro Glu Ala Lys Trp Ile Ser Asp Thr Glu Phe Ile Tyr Arg Glu 
                85                  90                  95      


Gln Lys Gly Thr Val Arg Leu Trp Asn Val Glu Thr Asn Thr Ser Thr 
            100                 105                 110         


Val Leu Ile Glu Gly Lys Lys Ile Glu Ser Leu Arg Ala Ile Arg Tyr 
        115                 120                 125             


Glu Ile Ser Pro Asp Arg Glu Tyr Ala Leu Phe Ser Tyr Asn Val Glu 
    130                 135                 140                 


Pro Ile Tyr Gln His Ser Tyr Thr Gly Tyr Tyr Val Leu Ser Lys Ile 
145                 150                 155                 160 


Pro His Gly Asp Pro Gln Ser Leu Asp Pro Pro Glu Val Ser Asn Ala 
                165                 170                 175     


Lys Leu Gln Tyr Ala Gly Trp Gly Pro Lys Gly Gln Gln Leu Ile Phe 
            180                 185                 190         


Ile Phe Glu Asn Asn Ile Tyr Tyr Cys Ala His Val Gly Lys Gln Ala 
        195                 200                 205             


Ile Arg Val Val Ser Thr Gly Lys Glu Gly Val Ile Tyr Asn Gly Leu 
    210                 215                 220                 


Ser Asp Trp Leu Tyr Glu Glu Glu Ile Leu Lys Thr His Ile Ala His 
225                 230                 235                 240 


Trp Trp Ser Pro Asp Gly Thr Arg Leu Ala Tyr Ala Ala Ile Asn Asp 
                245                 250                 255     


Ser Arg Val Pro Ile Met Glu Leu Pro Thr Tyr Thr Gly Ser Ile Tyr 
            260                 265                 270         


Pro Thr Val Lys Pro Tyr His Tyr Pro Lys Ala Gly Ser Glu Asn Pro 
        275                 280                 285             


Ser Ile Ser Leu His Val Ile Gly Leu Asn Gly Pro Thr His Asp Leu 
    290                 295                 300                 


Glu Met Met Pro Pro Asp Asp Pro Arg Met Arg Glu Tyr Tyr Ile Thr 
305                 310                 315                 320 


Met Val Lys Trp Ala Thr Ser Thr Lys Val Ala Val Thr Trp Leu Asn 
                325                 330                 335     


Arg Ala Gln Asn Val Ser Ile Leu Thr Leu Cys Asp Ala Thr Thr Gly 
            340                 345                 350         


Val Cys Thr Lys Lys His Glu Asp Glu Ser Glu Ala Trp Leu His Arg 
        355                 360                 365             


Gln Asn Glu Glu Pro Val Phe Ser Lys Asp Gly Arg Lys Phe Phe Phe 
    370                 375                 380                 


Ile Arg Ala Ile Pro Gln Gly Gly Arg Gly Lys Phe Tyr His Ile Thr 
385                 390                 395                 400 


Val Ser Ser Ser Gln Pro Asn Ser Ser Asn Asp Asn Ile Gln Ser Ile 
                405                 410                 415     


Thr Ser Gly Asp Trp Asp Val Thr Lys Ile Leu Ala Tyr Asp Glu Lys 
            420                 425                 430         


Gly Asn Lys Ile Tyr Phe Leu Ser Thr Glu Asp Leu Pro Arg Arg Arg 
        435                 440                 445             


Gln Leu Tyr Ser Ala Asn Thr Val Gly Asn Phe Asn Arg Gln Cys Leu 
    450                 455                 460                 


Ser Cys Asp Leu Val Glu Asn Cys Thr Tyr Phe Ser Ala Ser Phe Ser 
465                 470                 475                 480 


His Ser Met Asp Phe Phe Leu Leu Lys Cys Glu Gly Pro Gly Val Pro 
                485                 490                 495     


Met Val Thr Val His Asn Thr Thr Asp Lys Lys Lys Met Phe Asp Leu 
            500                 505                 510         


Glu Thr Asn Glu His Val Lys Lys Ala Ile Asn Asp Arg Gln Met Pro 
        515                 520                 525             


Lys Val Glu Tyr Arg Asp Ile Glu Ile Asp Asp Tyr Asn Leu Pro Met 
    530                 535                 540                 


Gln Ile Leu Lys Pro Ala Thr Phe Thr Asp Thr Thr His Tyr Pro Leu 
545                 550                 555                 560 


Leu Leu Val Val Asp Gly Thr Pro Gly Ser Gln Ser Val Ala Glu Lys 
                565                 570                 575     


Phe Glu Val Ser Trp Glu Thr Val Met Val Ser Ser His Gly Ala Val 
            580                 585                 590         


Val Val Lys Cys Asp Gly Arg Gly Ser Gly Phe Gln Gly Thr Lys Leu 
        595                 600                 605             


Leu His Glu Val Arg Arg Arg Leu Gly Leu Leu Glu Glu Lys Asp Gln 
    610                 615                 620                 


Met Glu Ala Val Arg Thr Met Leu Lys Glu Gln Tyr Ile Asp Arg Thr 
625                 630                 635                 640 


Arg Val Ala Val Phe Gly Lys Asp Tyr Gly Gly Tyr Leu Ser Thr Tyr 
                645                 650                 655     


Ile Leu Pro Ala Lys Gly Glu Asn Gln Gly Gln Thr Phe Thr Cys Gly 
            660                 665                 670         


Ser Ala Leu Ser Pro Ile Thr Asp Phe Lys Leu Tyr Ala Ser Ala Phe 
        675                 680                 685             


Ser Glu Arg Tyr Leu Gly Leu His Gly Leu Asp Asn Arg Ala Tyr Glu 
    690                 695                 700                 


Met Thr Lys Val Ala His Arg Val Ser Ala Leu Glu Glu Gln Gln Phe 
705                 710                 715                 720 


Leu Ile Ile His Pro Thr Ala Asp Glu Lys Ile His Phe Gln His Thr 
                725                 730                 735     


Ala Glu Leu Ile Thr Gln Leu Ile Arg Gly Lys Ala Asn Tyr Ser Leu 
            740                 745                 750         


Gln Ile Tyr Pro Asp Glu Ser His Tyr Phe Thr Ser Ser Ser Leu Lys 
        755                 760                 765             


Gln His Leu Tyr Arg Ser Ile Ile Asn Phe Phe Val Glu Cys Phe Arg 
    770                 775                 780                 


Ile Gln Asp Lys Leu Leu Thr Val Thr Ala Lys Glu Asp Glu Glu Glu 
785                 790                 795                 800 


Asp 
    


<210>  2685
<211>  204
<212>  PRT
<213>  homo sapiens

<400>  2685

Met Ala Lys Val Gln Val Asn Asn Val Val Val Leu Asp Asn Pro Ser 
1               5                   10                  15      


Pro Phe Tyr Asn Pro Phe Gln Phe Glu Ile Thr Phe Glu Cys Ile Glu 
            20                  25                  30          


Asp Leu Ser Glu Asp Leu Glu Trp Lys Ile Ile Tyr Val Gly Ser Ala 
        35                  40                  45              


Glu Ser Glu Glu Tyr Asp Gln Val Leu Asp Ser Val Leu Val Gly Pro 
    50                  55                  60                  


Val Pro Ala Gly Arg His Met Phe Val Phe Gln Ala Asp Ala Pro Asn 
65                  70                  75                  80  


Pro Gly Leu Ile Pro Asp Ala Asp Ala Val Gly Val Thr Val Val Leu 
                85                  90                  95      


Ile Thr Cys Thr Tyr Arg Gly Gln Glu Phe Ile Arg Val Gly Tyr Tyr 
            100                 105                 110         


Val Asn Asn Glu Tyr Thr Glu Thr Glu Leu Arg Glu Asn Pro Pro Val 
        115                 120                 125             


Lys Pro Asp Phe Ser Lys Leu Gln Arg Asn Ile Leu Ala Ser Asn Pro 
    130                 135                 140                 


Arg Val Thr Arg Phe His Ile Asn Trp Glu Asp Asn Thr Glu Lys Leu 
145                 150                 155                 160 


Glu Asp Ala Glu Ser Ser Asn Pro Asn Leu Gln Ser Leu Leu Ser Thr 
                165                 170                 175     


Asp Ala Leu Pro Ser Ala Ser Lys Gly Trp Ser Thr Ser Glu Asn Ser 
            180                 185                 190         


Leu Asn Val Met Leu Glu Ser His Met Asp Cys Met 
        195                 200                 


<210>  2686
<211>  211
<212>  PRT
<213>  homo sapiens

<400>  2686

Met Ser Cys Thr Ile Glu Lys Ile Leu Thr Asp Ala Lys Thr Leu Leu 
1               5                   10                  15      


Glu Arg Leu Arg Glu His Asp Ala Ala Ala Glu Ser Leu Val Asp Gln 
            20                  25                  30          


Ser Ala Ala Leu His Arg Arg Val Ala Ala Met Arg Glu Ala Gly Thr 
        35                  40                  45              


Ala Leu Pro Asp Gln Val Arg Gln Arg Tyr Gln Glu Asp Ala Ser Asp 
    50                  55                  60                  


Met Lys Asp Met Ser Lys Tyr Lys Pro His Ile Leu Leu Ser Gln Glu 
65                  70                  75                  80  


Asn Thr Gln Ile Arg Asp Leu Gln Gln Glu Asn Arg Glu Leu Trp Ile 
                85                  90                  95      


Ser Leu Glu Glu His Gln Asp Ala Leu Glu Leu Ile Met Ser Lys Tyr 
            100                 105                 110         


Arg Lys Gln Met Leu Gln Leu Met Val Ala Lys Lys Ala Val Asp Ala 
        115                 120                 125             


Glu Pro Val Leu Lys Ala His Gln Ser His Ser Ala Glu Ile Glu Ser 
    130                 135                 140                 


Gln Ile Asp Arg Ile Cys Glu Met Gly Glu Val Met Arg Lys Ala Val 
145                 150                 155                 160 


Gln Val Asp Asp Asp Gln Phe Cys Lys Ile Gln Glu Lys Leu Ala Gln 
                165                 170                 175     


Leu Glu Leu Glu Asn Lys Glu Leu Arg Glu Leu Leu Ser Ile Ser Ser 
            180                 185                 190         


Glu Ser Leu Gln Ala Arg Lys Glu Asn Ser Met Asp Thr Ala Ser Gln 
        195                 200                 205             


Ala Ile Lys 
    210     


<210>  2687
<211>  187
<212>  PRT
<213>  homo sapiens

<400>  2687

Met Pro Val Asp Leu Ser Lys Trp Ser Gly Pro Leu Ser Leu Gln Glu 
1               5                   10                  15      


Val Asp Glu Gln Pro Gln His Pro Leu His Val Thr Tyr Ala Gly Ala 
            20                  25                  30          


Ala Val Asp Glu Leu Gly Lys Val Leu Thr Pro Thr Gln Val Lys Asn 
        35                  40                  45              


Arg Pro Thr Ser Ile Ser Trp Asp Gly Leu Asp Ser Gly Lys Leu Tyr 
    50                  55                  60                  


Thr Leu Val Leu Thr Asp Pro Asp Ala Pro Ser Arg Lys Asp Pro Lys 
65                  70                  75                  80  


Tyr Arg Glu Trp His His Phe Leu Val Val Asn Met Lys Gly Asn Asp 
                85                  90                  95      


Ile Ser Ser Gly Thr Val Leu Ser Asp Tyr Val Gly Ser Gly Pro Pro 
            100                 105                 110         


Lys Gly Thr Gly Leu His Arg Tyr Val Trp Leu Val Tyr Glu Gln Asp 
        115                 120                 125             


Arg Pro Leu Lys Cys Asp Glu Pro Ile Leu Ser Asn Arg Ser Gly Asp 
    130                 135                 140                 


His Arg Gly Lys Phe Lys Val Ala Ser Phe Arg Lys Lys Tyr Glu Leu 
145                 150                 155                 160 


Arg Ala Pro Val Ala Gly Thr Cys Tyr Gln Ala Glu Trp Asp Asp Tyr 
                165                 170                 175     


Val Pro Lys Leu Tyr Glu Gln Leu Ser Gly Lys 
            180                 185         


<210>  2688
<211>  123
<212>  PRT
<213>  homo sapiens

<400>  2688

Met Ala Glu Lys Arg His Thr Arg Asp Ser Glu Ala Gln Arg Leu Pro 
1               5                   10                  15      


Asp Ser Phe Lys Asp Ser Pro Ser Lys Gly Leu Gly Pro Cys Gly Trp 
            20                  25                  30          


Ile Leu Val Ala Phe Ser Phe Leu Phe Thr Val Ile Thr Phe Pro Ile 
        35                  40                  45              


Ser Ile Trp Met Cys Ile Lys Val Ile Ala Ala Glu Gly Glu Met Asn 
    50                  55                  60                  


Ala Ser Arg Ala Leu Lys Glu Ala Ser Met Val Ile Thr Glu Ser Pro 
65                  70                  75                  80  


Ala Ala Leu Gln Leu Arg Tyr Leu Gln Thr Leu Thr Thr Ile Ala Ala 
                85                  90                  95      


Glu Lys Asn Ser Thr Ile Val Phe Pro Leu Pro Ile Asp Met Leu Gln 
            100                 105                 110         


Gly Ile Ile Gly Ala Lys His Ser His Leu Gly 
        115                 120             


<210>  2689
<211>  365
<212>  PRT
<213>  homo sapiens

<400>  2689

Met Ser Ser Ser Val Glu Gln Lys Lys Gly Pro Thr Arg Gln Arg Lys 
1               5                   10                  15      


Cys Gly Phe Cys Lys Ser Asn Arg Asp Lys Glu Cys Gly Gln Leu Leu 
            20                  25                  30          


Ile Ser Glu Asn Gln Lys Val Ala Ala His His Lys Cys Met Leu Phe 
        35                  40                  45              


Ser Ser Ala Leu Val Ser Ser His Ser Asp Asn Glu Ser Leu Gly Gly 
    50                  55                  60                  


Phe Ser Ile Glu Asp Val Gln Lys Glu Ile Lys Arg Gly Thr Lys Leu 
65                  70                  75                  80  


Met Cys Ser Leu Cys His Cys Pro Gly Ala Thr Ile Gly Cys Asp Val 
                85                  90                  95      


Lys Thr Cys His Arg Thr Tyr His Tyr His Cys Ala Leu His Asp Lys 
            100                 105                 110         


Ala Gln Ile Arg Glu Lys Pro Ser Gln Gly Ile Tyr Met Val Tyr Cys 
        115                 120                 125             


Arg Lys His Lys Lys Thr Ala His Asn Ser Glu Ala Asp Leu Glu Glu 
    130                 135                 140                 


Ser Phe Asn Glu His Glu Leu Glu Pro Ser Ser Pro Lys Ser Lys Lys 
145                 150                 155                 160 


Lys Ser Arg Lys Gly Arg Pro Arg Lys Thr Asn Phe Lys Gly Leu Ser 
                165                 170                 175     


Glu Asp Thr Arg Ser Thr Ser Ser His Gly Thr Asp Glu Met Glu Ser 
            180                 185                 190         


Ser Ser Tyr Arg Asp Arg Ser Pro His Arg Ser Ser Pro Ser Asp Thr 
        195                 200                 205             


Arg Pro Lys Cys Gly Phe Cys His Val Gly Glu Glu Glu Asn Glu Ala 
    210                 215                 220                 


Arg Gly Lys Leu His Ile Phe Asn Ala Lys Lys Ala Ala Ala His Tyr 
225                 230                 235                 240 


Lys Cys Met Leu Phe Ser Ser Gly Thr Val Gln Leu Thr Thr Thr Ser 
                245                 250                 255     


Arg Ala Glu Phe Gly Asp Phe Asp Ile Lys Thr Val Leu Gln Glu Ile 
            260                 265                 270         


Lys Arg Gly Lys Arg Met Lys Cys Thr Leu Cys Ser Gln Pro Gly Ala 
        275                 280                 285             


Thr Ile Gly Cys Glu Ile Lys Ala Cys Val Lys Thr Tyr His Tyr His 
    290                 295                 300                 


Cys Gly Val Gln Asp Lys Ala Lys Tyr Ile Glu Asn Met Ser Arg Gly 
305                 310                 315                 320 


Ile Tyr Lys Leu Tyr Cys Lys Asn His Ser Gly Asn Asp Glu Arg Asp 
                325                 330                 335     


Glu Glu Asp Glu Glu Arg Glu Ser Lys Ser Arg Gly Lys Val Glu Ile 
            340                 345                 350         


Asp Gln Gln Gln Leu Thr Gln Gln Gln Leu Asn Gly Asn 
        355                 360                 365 


<210>  2690
<211>  1071
<212>  PRT
<213>  homo sapiens

<400>  2690

Met Thr Ser Pro Ala Lys Phe Lys Lys Asp Lys Glu Ile Ile Ala Glu 
1               5                   10                  15      


Tyr Asp Thr Gln Val Lys Glu Ile Arg Ala Gln Leu Thr Glu Gln Met 
            20                  25                  30          


Lys Cys Leu Asp Gln Gln Cys Glu Leu Arg Val Gln Leu Leu Gln Asp 
        35                  40                  45              


Leu Gln Asp Phe Phe Arg Lys Lys Ala Glu Ile Glu Met Asp Tyr Ser 
    50                  55                  60                  


Arg Asn Leu Glu Lys Leu Ala Glu Arg Phe Leu Ala Lys Thr Arg Ser 
65                  70                  75                  80  


Thr Lys Asp Gln Gln Phe Lys Lys Asp Gln Asn Val Leu Ser Pro Val 
                85                  90                  95      


Asn Cys Trp Asn Leu Leu Leu Asn Gln Val Lys Arg Glu Ser Arg Asp 
            100                 105                 110         


His Thr Thr Leu Ser Asp Ile Tyr Leu Asn Asn Ile Ile Pro Arg Phe 
        115                 120                 125             


Val Gln Val Ser Glu Asp Ser Gly Arg Leu Phe Lys Lys Ser Lys Glu 
    130                 135                 140                 


Val Gly Gln Gln Leu Gln Asp Asp Leu Met Lys Val Leu Asn Glu Leu 
145                 150                 155                 160 


Tyr Ser Val Met Lys Thr Tyr His Met Tyr Asn Ala Asp Ser Ile Ser 
                165                 170                 175     


Ala Gln Ser Lys Leu Lys Glu Ala Glu Lys Gln Glu Glu Lys Gln Ile 
            180                 185                 190         


Gly Lys Ser Val Lys Gln Glu Asp Arg Gln Thr Pro Arg Ser Pro Asp 
        195                 200                 205             


Ser Thr Ala Asn Val Arg Ile Glu Glu Lys His Val Arg Arg Ser Ser 
    210                 215                 220                 


Val Lys Lys Ile Glu Lys Met Lys Glu Lys Arg Gln Ala Lys Tyr Thr 
225                 230                 235                 240 


Glu Asn Lys Leu Lys Ala Ile Lys Ala Arg Asn Glu Tyr Leu Leu Ala 
                245                 250                 255     


Leu Glu Ala Thr Asn Ala Ser Val Phe Lys Tyr Tyr Ile His Asp Leu 
            260                 265                 270         


Ser Asp Leu Ile Asp Gln Cys Cys Asp Leu Gly Tyr His Ala Ser Leu 
        275                 280                 285             


Asn Arg Ala Leu Arg Thr Phe Leu Ser Ala Glu Leu Asn Leu Glu Gln 
    290                 295                 300                 


Ser Lys His Glu Gly Leu Asp Ala Ile Glu Asn Ala Val Glu Asn Leu 
305                 310                 315                 320 


Asp Ala Thr Ser Asp Lys Gln Arg Leu Met Glu Met Tyr Asn Asn Val 
                325                 330                 335     


Phe Cys Pro Pro Met Lys Phe Glu Phe Gln Pro His Met Gly Asp Met 
            340                 345                 350         


Ala Ser Gln Leu Cys Ala Gln Gln Pro Val Gln Ser Glu Leu Val Gln 
        355                 360                 365             


Arg Cys Gln Gln Leu Gln Ser Arg Leu Ser Thr Leu Lys Ile Glu Asn 
    370                 375                 380                 


Glu Glu Val Lys Lys Thr Met Glu Ala Thr Leu Gln Thr Ile Gln Asp 
385                 390                 395                 400 


Ile Val Thr Val Glu Asp Phe Asp Val Ser Asp Cys Phe Gln Tyr Ser 
                405                 410                 415     


Asn Ser Met Glu Ser Val Lys Ser Thr Val Ser Glu Thr Phe Met Ser 
            420                 425                 430         


Lys Pro Ser Ile Ala Lys Arg Arg Ala Asn Gln Gln Glu Thr Glu Gln 
        435                 440                 445             


Phe Tyr Phe Thr Lys Met Lys Glu Tyr Leu Glu Gly Arg Asn Leu Ile 
    450                 455                 460                 


Thr Lys Leu Gln Ala Lys His Asp Leu Leu Gln Lys Thr Leu Gly Glu 
465                 470                 475                 480 


Ser Gln Arg Thr Asp Cys Ser Leu Ala Arg Arg Ser Ser Thr Val Arg 
                485                 490                 495     


Lys Gln Asp Ser Ser Gln Ala Ile Pro Leu Val Val Glu Ser Cys Ile 
            500                 505                 510         


Arg Phe Ile Ser Arg His Gly Leu Gln His Glu Gly Ile Phe Arg Val 
        515                 520                 525             


Ser Gly Ser Gln Val Glu Val Asn Asp Ile Lys Asn Ala Phe Glu Arg 
    530                 535                 540                 


Gly Glu Asp Pro Leu Ala Gly Asp Gln Asn Asp His Asp Met Asp Ser 
545                 550                 555                 560 


Ile Ala Gly Val Leu Lys Leu Tyr Phe Arg Gly Leu Glu His Pro Leu 
                565                 570                 575     


Phe Pro Lys Asp Ile Phe His Asp Leu Met Ala Cys Val Thr Met Asp 
            580                 585                 590         


Asn Leu Gln Glu Arg Ala Leu His Ile Arg Lys Val Leu Leu Val Leu 
        595                 600                 605             


Pro Lys Thr Thr Leu Ile Ile Met Arg Tyr Leu Phe Ala Phe Leu Asn 
    610                 615                 620                 


His Leu Ser Gln Phe Ser Glu Glu Asn Met Met Asp Pro Tyr Asn Leu 
625                 630                 635                 640 


Ala Ile Cys Phe Gly Pro Ser Leu Met Ser Val Pro Glu Gly His Asp 
                645                 650                 655     


Gln Val Ser Cys Gln Ala His Val Asn Glu Leu Ile Lys Thr Ile Ile 
            660                 665                 670         


Ile Gln His Glu Asn Ile Phe Pro Ser Pro Arg Glu Leu Glu Gly Pro 
        675                 680                 685             


Val Tyr Ser Arg Gly Gly Ser Met Glu Asp Tyr Cys Asp Ser Pro His 
    690                 695                 700                 


Gly Glu Thr Thr Ser Val Glu Asp Ser Thr Gln Asp Val Thr Ala Glu 
705                 710                 715                 720 


His His Thr Ser Asp Asp Glu Cys Glu Pro Ile Glu Ala Ile Ala Lys 
                725                 730                 735     


Phe Asp Tyr Val Gly Arg Thr Ala Arg Glu Leu Ser Phe Lys Lys Gly 
            740                 745                 750         


Ala Ser Leu Leu Leu Tyr Gln Arg Ala Ser Asp Asp Trp Trp Glu Gly 
        755                 760                 765             


Arg His Asn Gly Ile Asp Gly Leu Ile Pro His Gln Tyr Ile Val Val 
    770                 775                 780                 


Gln Asp Thr Glu Asp Gly Val Val Glu Arg Ser Ser Pro Lys Ser Glu 
785                 790                 795                 800 


Ile Glu Val Ile Ser Glu Pro Pro Glu Glu Lys Val Thr Ala Arg Ala 
                805                 810                 815     


Gly Ala Ser Cys Pro Ser Gly Gly His Val Ala Asp Ile Tyr Leu Ala 
            820                 825                 830         


Asn Ile Asn Lys Gln Arg Lys Arg Pro Glu Ser Gly Ser Ile Arg Lys 
        835                 840                 845             


Thr Phe Arg Ser Asp Ser His Gly Leu Ser Ser Ser Leu Thr Asp Ser 
    850                 855                 860                 


Ser Ser Pro Gly Val Gly Ala Ser Cys Arg Pro Ser Ser Gln Pro Ile 
865                 870                 875                 880 


Met Ser Gln Ser Leu Pro Lys Glu Gly Pro Asp Lys Cys Ser Ile Ser 
                885                 890                 895     


Gly His Gly Ser Leu Asn Ser Ile Ser Arg His Ser Ser Leu Lys Asn 
            900                 905                 910         


Arg Leu Asp Ser Pro Gln Ile Arg Lys Thr Ala Thr Ala Gly Arg Ser 
        915                 920                 925             


Lys Ser Phe Asn Asn His Arg Pro Met Asp Pro Glu Val Ile Ala Gln 
    930                 935                 940                 


Asp Ile Glu Ala Thr Met Asn Ser Ala Leu Asn Glu Leu Arg Glu Leu 
945                 950                 955                 960 


Glu Arg Gln Ser Ser Val Lys His Thr Pro Asp Val Val Leu Asp Thr 
                965                 970                 975     


Leu Glu Pro Leu Lys Thr Ser Pro Val Val Ala Pro Thr Ser Glu Pro 
            980                 985                 990         


Ser Ser Pro Leu His Thr Gln Leu  Leu Lys Asp Pro Glu  Pro Ala Phe 
        995                 1000                 1005             


Gln Arg  Ser Ala Ser Thr Ala  Gly Asp Ile Ala Cys  Ala Phe Arg 
    1010                 1015                 1020             


Pro Val  Lys Ser Val Lys Met  Ala Ala Pro Val Lys  Pro Pro Ala 
    1025                 1030                 1035             


Thr Arg  Pro Lys Pro Thr Val  Phe Pro Lys Thr Asn  Ala Thr Ser 
    1040                 1045                 1050             


Pro Gly  Val Asn Ser Ser Thr  Ser Pro Gln Ser Thr  Asp Lys Ser 
    1055                 1060                 1065             


Cys Thr  Val 
    1070     


<210>  2691
<211>  517
<212>  PRT
<213>  homo sapiens

<400>  2691

Met Pro Pro Pro Gly Lys Val Pro Arg Lys Glu Asn Leu Trp Leu Gln 
1               5                   10                  15      


Cys Glu Trp Gly Ser Cys Ser Phe Val Cys Ser Thr Met Glu Lys Phe 
            20                  25                  30          


Phe Glu His Val Thr Gln His Leu Gln Gln His Leu His Gly Ser Gly 
        35                  40                  45              


Glu Glu Glu Glu Glu Glu Glu Glu Asp Asp Pro Leu Glu Glu Glu Phe 
    50                  55                  60                  


Ser Cys Leu Trp Gln Glu Cys Gly Phe Cys Ser Leu Asp Ser Ser Ala 
65                  70                  75                  80  


Asp Leu Ile Arg His Val Tyr Phe His Cys Tyr His Thr Lys Leu Lys 
                85                  90                  95      


Gln Trp Gly Leu Gln Ala Leu Gln Ser Gln Ala Asp Leu Gly Pro Cys 
            100                 105                 110         


Ile Leu Asp Phe Gln Ser Arg Asn Val Ile Pro Asp Ile Pro Asp His 
        115                 120                 125             


Phe Leu Cys Leu Trp Glu His Cys Glu Asn Ser Phe Asp Asn Pro Glu 
    130                 135                 140                 


Trp Phe Tyr Arg His Val Glu Ala His Ser Leu Cys Cys Glu Tyr Glu 
145                 150                 155                 160 


Ala Val Gly Lys Asp Asn Pro Val Val Leu Cys Gly Trp Lys Gly Cys 
                165                 170                 175     


Thr Cys Thr Phe Lys Asp Arg Ser Lys Leu Arg Glu His Leu Arg Ser 
            180                 185                 190         


His Thr Gln Glu Lys Val Val Ala Cys Pro Thr Cys Gly Gly Met Phe 
        195                 200                 205             


Ala Asn Asn Thr Lys Phe Leu Asp His Ile Arg Arg Gln Thr Ser Leu 
    210                 215                 220                 


Asp Gln Gln His Phe Gln Cys Ser His Cys Ser Lys Arg Phe Ala Thr 
225                 230                 235                 240 


Glu Arg Leu Leu Arg Asp His Met Arg Asn His Val Asn His Tyr Lys 
                245                 250                 255     


Cys Pro Leu Cys Asp Met Thr Cys Pro Leu Pro Ser Ser Leu Arg Asn 
            260                 265                 270         


His Met Arg Phe Arg His Ser Glu Asp Arg Pro Phe Lys Cys Asp Cys 
        275                 280                 285             


Cys Asp Tyr Ser Cys Lys Asn Leu Ile Asp Leu Gln Lys His Leu Asp 
    290                 295                 300                 


Thr His Ser Glu Glu Pro Ala Tyr Arg Cys Asp Phe Glu Asn Cys Thr 
305                 310                 315                 320 


Phe Ser Ala Arg Ser Leu Cys Ser Ile Lys Ser His Tyr Arg Lys Val 
                325                 330                 335     


His Glu Gly Asp Ser Glu Pro Arg Tyr Lys Cys His Val Cys Asp Lys 
            340                 345                 350         


Cys Phe Thr Arg Gly Asn Asn Leu Thr Val His Leu Arg Lys Lys His 
        355                 360                 365             


Gln Phe Lys Trp Pro Ser Gly His Pro Arg Phe Arg Tyr Lys Glu His 
    370                 375                 380                 


Glu Asp Gly Tyr Met Arg Leu Gln Leu Val Arg Tyr Glu Ser Val Glu 
385                 390                 395                 400 


Leu Thr Gln Gln Leu Leu Arg Gln Pro Gln Glu Gly Ser Gly Leu Gly 
                405                 410                 415     


Thr Ser Leu Asn Glu Ser Ser Leu Gln Gly Ile Ile Leu Glu Thr Val 
            420                 425                 430         


Pro Gly Glu Pro Gly Arg Lys Glu Glu Glu Glu Glu Gly Lys Gly Ser 
        435                 440                 445             


Glu Gly Thr Ala Leu Ser Ala Ser Gln Asp Asn Pro Ser Ser Val Ile 
    450                 455                 460                 


His Val Val Asn Gln Thr Asn Ala Gln Gly Gln Gln Glu Ile Val Tyr 
465                 470                 475                 480 


Tyr Val Leu Ser Glu Ala Pro Gly Glu Pro Pro Pro Ala Pro Glu Pro 
                485                 490                 495     


Pro Ser Gly Gly Ile Met Glu Lys Leu Gln Gly Ile Ala Glu Glu Pro 
            500                 505                 510         


Glu Ile Gln Met Val 
        515         


<210>  2692
<211>  1474
<212>  PRT
<213>  homo sapiens

<400>  2692

Met Gly Lys Asn Lys Leu Leu His Pro Ser Leu Val Leu Leu Leu Leu 
1               5                   10                  15      


Val Leu Leu Pro Thr Asp Ala Ser Val Ser Gly Lys Pro Gln Tyr Met 
            20                  25                  30          


Val Leu Val Pro Ser Leu Leu His Thr Glu Thr Thr Glu Lys Gly Cys 
        35                  40                  45              


Val Leu Leu Ser Tyr Leu Asn Glu Thr Val Thr Val Ser Ala Ser Leu 
    50                  55                  60                  


Glu Ser Val Arg Gly Asn Arg Ser Leu Phe Thr Asp Leu Glu Ala Glu 
65                  70                  75                  80  


Asn Asp Val Leu His Cys Val Ala Phe Ala Val Pro Lys Ser Ser Ser 
                85                  90                  95      


Asn Glu Glu Val Met Phe Leu Thr Val Gln Val Lys Gly Pro Thr Gln 
            100                 105                 110         


Glu Phe Lys Lys Arg Thr Thr Val Met Val Lys Asn Glu Asp Ser Leu 
        115                 120                 125             


Val Phe Val Gln Thr Asp Lys Ser Ile Tyr Lys Pro Gly Gln Thr Val 
    130                 135                 140                 


Lys Phe Arg Val Val Ser Met Asp Glu Asn Phe His Pro Leu Asn Glu 
145                 150                 155                 160 


Leu Ile Pro Leu Val Tyr Ile Gln Asp Pro Lys Gly Asn Arg Ile Ala 
                165                 170                 175     


Gln Trp Gln Ser Phe Gln Leu Glu Gly Gly Leu Lys Gln Phe Ser Phe 
            180                 185                 190         


Pro Leu Ser Ser Glu Pro Phe Gln Gly Ser Tyr Lys Val Val Val Gln 
        195                 200                 205             


Lys Lys Ser Gly Gly Arg Thr Glu His Pro Phe Thr Val Glu Glu Phe 
    210                 215                 220                 


Val Leu Pro Lys Phe Glu Val Gln Val Thr Val Pro Lys Ile Ile Thr 
225                 230                 235                 240 


Ile Leu Glu Glu Glu Met Asn Val Ser Val Cys Gly Leu Tyr Thr Tyr 
                245                 250                 255     


Gly Lys Pro Val Pro Gly His Val Thr Val Ser Ile Cys Arg Lys Tyr 
            260                 265                 270         


Ser Asp Ala Ser Asp Cys His Gly Glu Asp Ser Gln Ala Phe Cys Glu 
        275                 280                 285             


Lys Phe Ser Gly Gln Leu Asn Ser His Gly Cys Phe Tyr Gln Gln Val 
    290                 295                 300                 


Lys Thr Lys Val Phe Gln Leu Lys Arg Lys Glu Tyr Glu Met Lys Leu 
305                 310                 315                 320 


His Thr Glu Ala Gln Ile Gln Glu Glu Gly Thr Val Val Glu Leu Thr 
                325                 330                 335     


Gly Arg Gln Ser Ser Glu Ile Thr Arg Thr Ile Thr Lys Leu Ser Phe 
            340                 345                 350         


Val Lys Val Asp Ser His Phe Arg Gln Gly Ile Pro Phe Phe Gly Gln 
        355                 360                 365             


Val Arg Leu Val Asp Gly Lys Gly Val Pro Ile Pro Asn Lys Val Ile 
    370                 375                 380                 


Phe Ile Arg Gly Asn Glu Ala Asn Tyr Tyr Ser Asn Ala Thr Thr Asp 
385                 390                 395                 400 


Glu His Gly Leu Val Gln Phe Ser Ile Asn Thr Thr Asn Val Met Gly 
                405                 410                 415     


Thr Ser Leu Thr Val Arg Val Asn Tyr Lys Asp Arg Ser Pro Cys Tyr 
            420                 425                 430         


Gly Tyr Gln Trp Val Ser Glu Glu His Glu Glu Ala His His Thr Ala 
        435                 440                 445             


Tyr Leu Val Phe Ser Pro Ser Lys Ser Phe Val His Leu Glu Pro Met 
    450                 455                 460                 


Ser His Glu Leu Pro Cys Gly His Thr Gln Thr Val Gln Ala His Tyr 
465                 470                 475                 480 


Ile Leu Asn Gly Gly Thr Leu Leu Gly Leu Lys Lys Leu Ser Phe Tyr 
                485                 490                 495     


Tyr Leu Ile Met Ala Lys Gly Gly Ile Val Arg Thr Gly Thr His Gly 
            500                 505                 510         


Leu Leu Val Lys Gln Glu Asp Met Lys Gly His Phe Ser Ile Ser Ile 
        515                 520                 525             


Pro Val Lys Ser Asp Ile Ala Pro Val Ala Arg Leu Leu Ile Tyr Ala 
    530                 535                 540                 


Val Leu Pro Thr Gly Asp Val Ile Gly Asp Ser Ala Lys Tyr Asp Val 
545                 550                 555                 560 


Glu Asn Cys Leu Ala Asn Lys Val Asp Leu Ser Phe Ser Pro Ser Gln 
                565                 570                 575     


Ser Leu Pro Ala Ser His Ala His Leu Arg Val Thr Ala Ala Pro Gln 
            580                 585                 590         


Ser Val Cys Ala Leu Arg Ala Val Asp Gln Ser Val Leu Leu Met Lys 
        595                 600                 605             


Pro Asp Ala Glu Leu Ser Ala Ser Ser Val Tyr Asn Leu Leu Pro Glu 
    610                 615                 620                 


Lys Asp Leu Thr Gly Phe Pro Gly Pro Leu Asn Asp Gln Asp Asp Glu 
625                 630                 635                 640 


Asp Cys Ile Asn Arg His Asn Val Tyr Ile Asn Gly Ile Thr Tyr Thr 
                645                 650                 655     


Pro Val Ser Ser Thr Asn Glu Lys Asp Met Tyr Ser Phe Leu Glu Asp 
            660                 665                 670         


Met Gly Leu Lys Ala Phe Thr Asn Ser Lys Ile Arg Lys Pro Lys Met 
        675                 680                 685             


Cys Pro Gln Leu Gln Gln Tyr Glu Met His Gly Pro Glu Gly Leu Arg 
    690                 695                 700                 


Val Gly Phe Tyr Glu Ser Asp Val Met Gly Arg Gly His Ala Arg Leu 
705                 710                 715                 720 


Val His Val Glu Glu Pro His Thr Glu Thr Val Arg Lys Tyr Phe Pro 
                725                 730                 735     


Glu Thr Trp Ile Trp Asp Leu Val Val Val Asn Ser Ala Gly Val Ala 
            740                 745                 750         


Glu Val Gly Val Thr Val Pro Asp Thr Ile Thr Glu Trp Lys Ala Gly 
        755                 760                 765             


Ala Phe Cys Leu Ser Glu Asp Ala Gly Leu Gly Ile Ser Ser Thr Ala 
    770                 775                 780                 


Ser Leu Arg Ala Phe Gln Pro Phe Phe Val Glu Leu Thr Met Pro Tyr 
785                 790                 795                 800 


Ser Val Ile Arg Gly Glu Ala Phe Thr Leu Lys Ala Thr Val Leu Asn 
                805                 810                 815     


Tyr Leu Pro Lys Cys Ile Arg Val Ser Val Gln Leu Glu Ala Ser Pro 
            820                 825                 830         


Ala Phe Leu Ala Val Pro Val Glu Lys Glu Gln Ala Pro His Cys Ile 
        835                 840                 845             


Cys Ala Asn Gly Arg Gln Thr Val Ser Trp Ala Val Thr Pro Lys Ser 
    850                 855                 860                 


Leu Gly Asn Val Asn Phe Thr Val Ser Ala Glu Ala Leu Glu Ser Gln 
865                 870                 875                 880 


Glu Leu Cys Gly Thr Glu Val Pro Ser Val Pro Glu His Gly Arg Lys 
                885                 890                 895     


Asp Thr Val Ile Lys Pro Leu Leu Val Glu Pro Glu Gly Leu Glu Lys 
            900                 905                 910         


Glu Thr Thr Phe Asn Ser Leu Leu Cys Pro Ser Gly Gly Glu Val Ser 
        915                 920                 925             


Glu Glu Leu Ser Leu Lys Leu Pro Pro Asn Val Val Glu Glu Ser Ala 
    930                 935                 940                 


Arg Ala Ser Val Ser Val Leu Gly Asp Ile Leu Gly Ser Ala Met Gln 
945                 950                 955                 960 


Asn Thr Gln Asn Leu Leu Gln Met Pro Tyr Gly Cys Gly Glu Gln Asn 
                965                 970                 975     


Met Val Leu Phe Ala Pro Asn Ile Tyr Val Leu Asp Tyr Leu Asn Glu 
            980                 985                 990         


Thr Gln Gln Leu Thr Pro Glu Ile  Lys Ser Lys Ala Ile  Gly Tyr Leu 
        995                 1000                 1005             


Asn Thr  Gly Tyr Gln Arg Gln  Leu Asn Tyr Lys His  Tyr Asp Gly 
    1010                 1015                 1020             


Ser Tyr  Ser Thr Phe Gly Glu  Arg Tyr Gly Arg Asn  Gln Gly Asn 
    1025                 1030                 1035             


Thr Trp  Leu Thr Ala Phe Val  Leu Lys Thr Phe Ala  Gln Ala Arg 
    1040                 1045                 1050             


Ala Tyr  Ile Phe Ile Asp Glu  Ala His Ile Thr Gln  Ala Leu Ile 
    1055                 1060                 1065             


Trp Leu  Ser Gln Arg Gln Lys  Asp Asn Gly Cys Phe  Arg Ser Ser 
    1070                 1075                 1080             


Gly Ser  Leu Leu Asn Asn Ala  Ile Lys Gly Gly Val  Glu Asp Glu 
    1085                 1090                 1095             


Val Thr  Leu Ser Ala Tyr Ile  Thr Ile Ala Leu Leu  Glu Ile Pro 
    1100                 1105                 1110             


Leu Thr  Val Thr His Pro Val  Val Arg Asn Ala Leu  Phe Cys Leu 
    1115                 1120                 1125             


Glu Ser  Ala Trp Lys Thr Ala  Gln Glu Gly Asp His  Gly Ser His 
    1130                 1135                 1140             


Val Tyr  Thr Lys Ala Leu Leu  Ala Tyr Ala Phe Ala  Leu Ala Gly 
    1145                 1150                 1155             


Asn Gln  Asp Lys Arg Lys Glu  Val Leu Lys Ser Leu  Asn Glu Glu 
    1160                 1165                 1170             


Ala Val  Lys Lys Asp Asn Ser  Val His Trp Glu Arg  Pro Gln Lys 
    1175                 1180                 1185             


Pro Lys  Ala Pro Val Gly His  Phe Tyr Glu Pro Gln  Ala Pro Ser 
    1190                 1195                 1200             


Ala Glu  Val Glu Met Thr Ser  Tyr Val Leu Leu Ala  Tyr Leu Thr 
    1205                 1210                 1215             


Ala Gln  Pro Ala Pro Thr Ser  Glu Asp Leu Thr Ser  Ala Thr Asn 
    1220                 1225                 1230             


Ile Val  Lys Trp Ile Thr Lys  Gln Gln Asn Ala Gln  Gly Gly Phe 
    1235                 1240                 1245             


Ser Ser  Thr Gln Asp Thr Val  Val Ala Leu His Ala  Leu Ser Lys 
    1250                 1255                 1260             


Tyr Gly  Ala Ala Thr Phe Thr  Arg Thr Gly Lys Ala  Ala Gln Val 
    1265                 1270                 1275             


Thr Ile  Gln Ser Ser Gly Thr  Phe Ser Ser Lys Phe  Gln Val Asp 
    1280                 1285                 1290             


Asn Asn  Asn Arg Leu Leu Leu  Gln Gln Val Ser Leu  Pro Glu Leu 
    1295                 1300                 1305             


Pro Gly  Glu Tyr Ser Met Lys  Val Thr Gly Glu Gly  Cys Val Tyr 
    1310                 1315                 1320             


Leu Gln  Thr Ser Leu Lys Tyr  Asn Ile Leu Pro Glu  Lys Glu Glu 
    1325                 1330                 1335             


Phe Pro  Phe Ala Leu Gly Val  Gln Thr Leu Pro Gln  Thr Cys Asp 
    1340                 1345                 1350             


Glu Pro  Lys Ala His Thr Ser  Phe Gln Ile Ser Leu  Ser Val Ser 
    1355                 1360                 1365             


Tyr Thr  Gly Ser Arg Ser Ala  Ser Asn Met Ala Ile  Val Asp Val 
    1370                 1375                 1380             


Lys Met  Val Ser Gly Phe Ile  Pro Leu Lys Pro Thr  Val Lys Met 
    1385                 1390                 1395             


Leu Glu  Arg Ser Asn His Val  Ser Arg Thr Glu Val  Ser Ser Asn 
    1400                 1405                 1410             


His Val  Leu Ile Tyr Leu Asp  Lys Val Ser Asn Gln  Thr Leu Ser 
    1415                 1420                 1425             


Leu Phe  Phe Thr Val Leu Gln  Asp Val Pro Val Arg  Asp Leu Lys 
    1430                 1435                 1440             


Pro Ala  Ile Val Lys Val Tyr  Asp Tyr Tyr Glu Thr  Asp Glu Phe 
    1445                 1450                 1455             


Ala Ile  Ala Glu Tyr Asn Ala  Pro Cys Ser Lys Asp  Leu Gly Asn 
    1460                 1465                 1470             


Ala 
    


<210>  2693
<211>  722
<212>  PRT
<213>  homo sapiens

<400>  2693

Met Ala Gln Trp Asn Gln Leu Gln Gln Leu Asp Thr Arg Tyr Leu Glu 
1               5                   10                  15      


Gln Leu His Gln Leu Tyr Ser Asp Ser Phe Pro Met Glu Leu Arg Gln 
            20                  25                  30          


Phe Leu Ala Pro Trp Ile Glu Ser Gln Asp Trp Ala Tyr Ala Ala Ser 
        35                  40                  45              


Lys Glu Ser His Ala Thr Leu Val Phe His Asn Leu Leu Gly Glu Ile 
    50                  55                  60                  


Asp Gln Gln Tyr Ser Arg Phe Leu Gln Glu Ser Asn Val Leu Tyr Gln 
65                  70                  75                  80  


His Asn Leu Arg Arg Ile Lys Gln Phe Leu Gln Ser Arg Tyr Leu Glu 
                85                  90                  95      


Lys Pro Met Glu Ile Ala Arg Ile Val Ala Arg Cys Leu Trp Glu Glu 
            100                 105                 110         


Ser Arg Leu Leu Gln Thr Ala Ala Thr Ala Ala Gln Gln Gly Gly Gln 
        115                 120                 125             


Ala Asn His Pro Thr Ala Ala Val Val Thr Glu Lys Gln Gln Met Leu 
    130                 135                 140                 


Glu Gln His Leu Gln Asp Val Arg Lys Arg Val Gln Asp Leu Glu Gln 
145                 150                 155                 160 


Lys Met Lys Val Val Glu Asn Leu Gln Asp Asp Phe Asp Phe Asn Tyr 
                165                 170                 175     


Lys Thr Leu Lys Ser Gln Gly Asp Met Gln Asp Leu Asn Gly Asn Asn 
            180                 185                 190         


Gln Ser Val Thr Arg Gln Lys Met Gln Gln Leu Glu Gln Met Leu Thr 
        195                 200                 205             


Ala Leu Asp Gln Met Arg Arg Ser Ile Val Ser Glu Leu Ala Gly Leu 
    210                 215                 220                 


Leu Ser Ala Met Glu Tyr Val Gln Lys Thr Leu Thr Asp Glu Glu Leu 
225                 230                 235                 240 


Ala Asp Trp Lys Arg Arg Gln Gln Ile Ala Cys Ile Gly Gly Pro Pro 
                245                 250                 255     


Asn Ile Cys Leu Asp Arg Leu Glu Asn Trp Ile Thr Ser Leu Ala Glu 
            260                 265                 270         


Ser Gln Leu Gln Thr Arg Gln Gln Ile Lys Lys Leu Glu Glu Leu Gln 
        275                 280                 285             


Gln Lys Val Ser Tyr Lys Gly Asp Pro Ile Val Gln His Arg Pro Met 
    290                 295                 300                 


Leu Glu Glu Arg Ile Val Glu Leu Phe Arg Asn Leu Met Lys Ser Ala 
305                 310                 315                 320 


Phe Val Val Glu Arg Gln Pro Cys Met Pro Met His Pro Asp Arg Pro 
                325                 330                 335     


Leu Val Ile Lys Thr Gly Val Gln Phe Thr Thr Lys Val Arg Leu Leu 
            340                 345                 350         


Val Lys Phe Pro Glu Leu Asn Tyr Gln Leu Lys Ile Lys Val Cys Ile 
        355                 360                 365             


Asp Lys Asp Ser Gly Asp Val Ala Ala Leu Arg Gly Ser Arg Lys Phe 
    370                 375                 380                 


Asn Ile Leu Gly Thr Asn Thr Lys Val Met Asn Met Glu Glu Ser Asn 
385                 390                 395                 400 


Asn Gly Ser Leu Ser Ala Glu Phe Lys His Leu Thr Leu Arg Glu Gln 
                405                 410                 415     


Arg Cys Gly Asn Gly Gly Arg Ala Asn Cys Asp Ala Ser Leu Ile Val 
            420                 425                 430         


Thr Glu Glu Leu His Leu Ile Thr Phe Glu Thr Glu Val Tyr His Gln 
        435                 440                 445             


Gly Leu Lys Ile Asp Leu Glu Thr His Ser Leu Pro Val Val Val Ile 
    450                 455                 460                 


Ser Asn Ile Cys Gln Met Pro Asn Ala Trp Ala Ser Ile Leu Trp Tyr 
465                 470                 475                 480 


Asn Met Leu Thr Asn Asn Pro Lys Asn Val Asn Phe Phe Thr Lys Pro 
                485                 490                 495     


Pro Ile Gly Thr Trp Asp Gln Val Ala Glu Val Leu Ser Trp Gln Phe 
            500                 505                 510         


Ser Ser Thr Thr Lys Arg Gly Leu Ser Ile Glu Gln Leu Thr Thr Leu 
        515                 520                 525             


Ala Glu Lys Leu Leu Gly Pro Gly Val Asn Tyr Ser Gly Cys Gln Ile 
    530                 535                 540                 


Thr Trp Ala Lys Phe Cys Lys Glu Asn Met Ala Gly Lys Gly Phe Ser 
545                 550                 555                 560 


Phe Trp Val Trp Leu Asp Asn Ile Ile Asp Leu Val Lys Lys Tyr Ile 
                565                 570                 575     


Leu Ala Leu Trp Asn Glu Gly Tyr Ile Met Gly Phe Ile Ser Lys Glu 
            580                 585                 590         


Arg Glu Arg Ala Ile Leu Ser Thr Lys Pro Pro Gly Thr Phe Leu Leu 
        595                 600                 605             


Arg Phe Ser Glu Ser Ser Lys Glu Gly Gly Val Thr Phe Thr Trp Val 
    610                 615                 620                 


Glu Lys Asp Ile Ser Gly Lys Thr Gln Ile Gln Ser Val Glu Pro Tyr 
625                 630                 635                 640 


Thr Lys Gln Gln Leu Asn Asn Met Ser Phe Ala Glu Ile Ile Met Gly 
                645                 650                 655     


Tyr Lys Ile Met Asp Ala Thr Asn Ile Leu Val Ser Pro Leu Val Tyr 
            660                 665                 670         


Leu Tyr Pro Asp Ile Pro Lys Glu Glu Ala Phe Gly Lys Tyr Cys Arg 
        675                 680                 685             


Pro Glu Ser Gln Glu His Pro Glu Ala Asp Pro Gly Ser Ala Ala Pro 
    690                 695                 700                 


Tyr Leu Lys Thr Lys Phe Ile Cys Val Thr Pro Phe Ile Asp Ala Val 
705                 710                 715                 720 


Trp Lys 
        


<210>  2694
<211>  392
<212>  PRT
<213>  homo sapiens

<400>  2694

Met Ala Val Val Ala Ala Ala Ala Gly Trp Leu Leu Arg Leu Arg Ala 
1               5                   10                  15      


Ala Gly Ala Glu Gly His Trp Arg Arg Leu Pro Gly Ala Gly Leu Ala 
            20                  25                  30          


Arg Gly Phe Leu His Pro Ala Ala Thr Val Glu Asp Ala Ala Gln Arg 
        35                  40                  45              


Arg Gln Val Ala His Phe Thr Phe Gln Pro Asp Pro Glu Pro Arg Glu 
    50                  55                  60                  


Tyr Gly Gln Thr Gln Lys Met Asn Leu Phe Gln Ser Val Thr Ser Ala 
65                  70                  75                  80  


Leu Asp Asn Ser Leu Ala Lys Asp Pro Thr Ala Val Ile Phe Gly Glu 
                85                  90                  95      


Asp Val Ala Phe Gly Gly Val Phe Arg Cys Thr Val Gly Leu Arg Asp 
            100                 105                 110         


Lys Tyr Gly Lys Asp Arg Val Phe Asn Thr Pro Leu Cys Glu Gln Gly 
        115                 120                 125             


Ile Val Gly Phe Gly Ile Gly Ile Ala Val Thr Gly Ala Thr Ala Ile 
    130                 135                 140                 


Ala Glu Ile Gln Phe Ala Asp Tyr Ile Phe Pro Ala Phe Asp Gln Ile 
145                 150                 155                 160 


Val Asn Glu Ala Ala Lys Tyr Arg Tyr Arg Ser Gly Asp Leu Phe Asn 
                165                 170                 175     


Cys Gly Ser Leu Thr Ile Arg Ser Pro Trp Gly Cys Val Gly His Gly 
            180                 185                 190         


Ala Leu Tyr His Ser Gln Ser Pro Glu Ala Phe Phe Ala His Cys Pro 
        195                 200                 205             


Gly Ile Lys Val Val Ile Pro Arg Ser Pro Phe Gln Ala Lys Gly Leu 
    210                 215                 220                 


Leu Leu Ser Cys Ile Glu Asp Lys Asn Pro Cys Ile Phe Phe Glu Pro 
225                 230                 235                 240 


Lys Ile Leu Tyr Arg Ala Ala Ala Glu Glu Val Pro Ile Glu Pro Tyr 
                245                 250                 255     


Asn Ile Pro Leu Ser Gln Ala Glu Val Ile Gln Glu Gly Ser Asp Val 
            260                 265                 270         


Thr Leu Val Ala Trp Gly Thr Gln Val His Val Ile Arg Glu Val Ala 
        275                 280                 285             


Ser Met Ala Lys Glu Lys Leu Gly Val Ser Cys Glu Val Ile Asp Leu 
    290                 295                 300                 


Arg Thr Ile Ile Pro Trp Asp Val Asp Thr Ile Cys Lys Ser Val Ile 
305                 310                 315                 320 


Lys Thr Gly Arg Leu Leu Ile Ser His Glu Ala Pro Leu Thr Gly Gly 
                325                 330                 335     


Phe Ala Ser Glu Ile Ser Ser Thr Val Gln Glu Glu Cys Phe Leu Asn 
            340                 345                 350         


Leu Glu Ala Pro Ile Ser Arg Val Cys Gly Tyr Asp Thr Pro Phe Pro 
        355                 360                 365             


His Ile Phe Glu Pro Phe Tyr Ile Pro Asp Lys Trp Lys Cys Tyr Asp 
    370                 375                 380                 


Ala Leu Arg Lys Met Ile Asn Tyr 
385                 390         


<210>  2695
<211>  794
<212>  PRT
<213>  homo sapiens

<400>  2695

Met Asn Ile Asp Asp Lys Leu Glu Gly Leu Phe Leu Lys Cys Gly Gly 
1               5                   10                  15      


Ile Asp Glu Met Gln Ser Ser Arg Thr Met Val Val Met Gly Gly Val 
            20                  25                  30          


Ser Gly Gln Ser Thr Val Ser Gly Glu Leu Gln Asp Ser Val Leu Gln 
        35                  40                  45              


Asp Arg Ser Met Pro His Gln Glu Ile Leu Ala Ala Asp Glu Val Leu 
    50                  55                  60                  


Gln Glu Ser Glu Met Arg Gln Gln Asp Met Ile Ser His Asp Glu Leu 
65                  70                  75                  80  


Met Val His Glu Glu Thr Val Lys Asn Asp Glu Glu Gln Met Glu Thr 
                85                  90                  95      


His Glu Arg Leu Pro Gln Gly Leu Gln Tyr Ala Leu Asn Val Pro Ile 
            100                 105                 110         


Ser Val Lys Gln Glu Ile Thr Phe Thr Asp Val Ser Glu Gln Leu Met 
        115                 120                 125             


Arg Asp Lys Lys Gln Ile Arg Glu Pro Val Asp Leu Gln Lys Lys Lys 
    130                 135                 140                 


Lys Arg Lys Gln Arg Ser Pro Ala Lys Ile Leu Thr Ile Asn Glu Asp 
145                 150                 155                 160 


Gly Ser Leu Gly Leu Lys Thr Pro Lys Ser His Val Cys Glu His Cys 
                165                 170                 175     


Asn Ala Ala Phe Arg Thr Asn Tyr His Leu Gln Arg His Val Phe Ile 
            180                 185                 190         


His Thr Gly Glu Lys Pro Phe Gln Cys Ser Gln Cys Asp Met Arg Phe 
        195                 200                 205             


Ile Gln Lys Tyr Leu Leu Gln Arg His Glu Lys Ile His Thr Gly Glu 
    210                 215                 220                 


Lys Pro Phe Arg Cys Asp Glu Cys Gly Met Arg Phe Ile Gln Lys Tyr 
225                 230                 235                 240 


His Met Glu Arg His Lys Arg Thr His Ser Gly Glu Lys Pro Tyr Gln 
                245                 250                 255     


Cys Glu Tyr Cys Leu Gln Tyr Phe Ser Arg Thr Asp Arg Val Leu Lys 
            260                 265                 270         


His Lys Arg Met Cys His Glu Asn His Asp Lys Lys Leu Asn Arg Cys 
        275                 280                 285             


Ala Ile Lys Gly Gly Leu Leu Thr Ser Glu Glu Asp Ser Gly Phe Ser 
    290                 295                 300                 


Thr Ser Pro Lys Asp Asn Ser Leu Pro Lys Lys Lys Arg Gln Lys Thr 
305                 310                 315                 320 


Glu Lys Lys Ser Ser Gly Met Asp Lys Glu Ser Ala Leu Asp Lys Ser 
                325                 330                 335     


Asp Leu Lys Lys Asp Lys Asn Asp Tyr Leu Pro Leu Tyr Ser Ser Ser 
            340                 345                 350         


Thr Lys Val Lys Asp Glu Tyr Met Val Ala Glu Tyr Ala Val Glu Met 
        355                 360                 365             


Pro His Ser Ser Val Gly Gly Ser His Leu Glu Asp Ala Ser Gly Glu 
    370                 375                 380                 


Ile His Pro Pro Lys Leu Val Leu Lys Lys Ile Asn Ser Lys Arg Ser 
385                 390                 395                 400 


Leu Lys Gln Pro Leu Glu Gln Asn Gln Thr Ile Ser Pro Leu Ser Thr 
                405                 410                 415     


Tyr Glu Glu Ser Lys Val Ser Lys Tyr Ala Phe Glu Leu Val Asp Lys 
            420                 425                 430         


Gln Ala Leu Leu Asp Ser Glu Gly Asn Ala Asp Ile Asp Gln Val Asp 
        435                 440                 445             


Asn Leu Gln Glu Gly Pro Ser Lys Pro Val His Ser Ser Thr Asn Tyr 
    450                 455                 460                 


Asp Asp Ala Met Gln Phe Leu Lys Lys Lys Arg Tyr Leu Gln Ala Ala 
465                 470                 475                 480 


Ser Asn Asn Ser Arg Glu Tyr Ala Leu Asn Val Gly Thr Ile Ala Ser 
                485                 490                 495     


Gln Pro Ser Val Thr Gln Ala Ala Val Ala Ser Val Ile Asp Glu Ser 
            500                 505                 510         


Thr Thr Ala Ser Ile Leu Glu Ser Gln Ala Leu Asn Val Glu Ile Lys 
        515                 520                 525             


Ser Asn His Asp Lys Asn Val Ile Pro Asp Glu Val Leu Gln Thr Leu 
    530                 535                 540                 


Leu Asp His Tyr Ser His Lys Ala Asn Gly Gln His Glu Ile Ser Phe 
545                 550                 555                 560 


Ser Val Ala Asp Thr Glu Val Thr Ser Ser Ile Ser Ile Asn Ser Ser 
                565                 570                 575     


Glu Val Pro Glu Val Thr Pro Ser Glu Asn Val Gly Ser Ser Ser Gln 
            580                 585                 590         


Ala Ser Ser Ser Asp Lys Ala Asn Met Leu Gln Glu Tyr Ser Lys Phe 
        595                 600                 605             


Leu Gln Gln Ala Leu Asp Arg Thr Ser Gln Asn Asp Ala Tyr Leu Asn 
    610                 615                 620                 


Ser Pro Ser Leu Asn Phe Val Thr Asp Asn Gln Thr Leu Pro Asn Gln 
625                 630                 635                 640 


Pro Ala Phe Ser Ser Ile Asp Lys Gln Val Tyr Ala Thr Met Pro Ile 
                645                 650                 655     


Asn Ser Phe Arg Ser Gly Met Asn Ser Pro Leu Arg Thr Thr Pro Asp 
            660                 665                 670         


Lys Ser His Phe Gly Leu Ile Val Gly Asp Ser Gln His Ser Phe Pro 
        675                 680                 685             


Phe Ser Gly Asp Glu Thr Asn His Ala Ser Ala Thr Ser Thr Gln Asp 
    690                 695                 700                 


Phe Leu Asp Gln Val Thr Ser Gln Lys Lys Ala Glu Ala Gln Pro Val 
705                 710                 715                 720 


His Gln Ala Tyr Gln Met Ser Ser Phe Glu Gln Pro Phe Arg Ala Pro 
                725                 730                 735     


Tyr His Gly Ser Arg Ala Gly Ile Ala Thr Gln Phe Ser Thr Ala Asn 
            740                 745                 750         


Gly Gln Val Asn Leu Arg Gly Pro Gly Thr Ser Ala Glu Phe Ser Glu 
        755                 760                 765             


Phe Pro Leu Val Asn Val Asn Asp Asn Arg Ala Gly Met Thr Ser Ser 
    770                 775                 780                 


Pro Asp Ala Thr Thr Gly Gln Thr Phe Gly 
785                 790                 


<210>  2696
<211>  460
<212>  PRT
<213>  homo sapiens

<400>  2696

Met Ala Glu Ser Glu Asn Arg Lys Glu Leu Ser Glu Ser Ser Gln Glu 
1               5                   10                  15      


Glu Ala Gly Asn Gln Ile Met Val Glu Gly Leu Gly Glu His Leu Glu 
            20                  25                  30          


Arg Gly Glu Asp Ala Ala Ala Gly Leu Gly Asp Asp Gly Lys Cys Gly 
        35                  40                  45              


Glu Glu Ala Ala Ala Gly Leu Gly Glu Glu Gly Glu Asn Gly Glu Asp 
    50                  55                  60                  


Thr Ala Ala Gly Ser Gly Glu Asp Gly Lys Lys Gly Gly Asp Thr Asp 
65                  70                  75                  80  


Glu Asp Ser Glu Ala Asp Arg Pro Lys Gly Leu Ile Gly Tyr Val Leu 
                85                  90                  95      


Asp Thr Asp Phe Val Glu Ser Leu Pro Val Lys Val Lys Tyr Arg Val 
            100                 105                 110         


Leu Ala Leu Lys Lys Leu Gln Thr Arg Ala Ala Asn Leu Glu Ser Lys 
        115                 120                 125             


Phe Leu Arg Glu Phe His Asp Ile Glu Arg Lys Phe Ala Glu Met Tyr 
    130                 135                 140                 


Gln Pro Leu Leu Glu Lys Arg Arg Gln Ile Ile Asn Ala Ile Tyr Glu 
145                 150                 155                 160 


Pro Thr Glu Glu Glu Cys Glu Tyr Lys Ser Asp Ser Glu Asp Cys Asp 
                165                 170                 175     


Asp Glu Glu Met Cys His Glu Glu Met Tyr Gly Asn Glu Glu Gly Met 
            180                 185                 190         


Val His Glu Tyr Val Asp Glu Asp Asp Gly Tyr Glu Asp Tyr Tyr Tyr 
        195                 200                 205             


Asp Tyr Ala Val Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp Asp Ile 
    210                 215                 220                 


Glu Ala Thr Gly Glu Glu Asn Lys Glu Glu Glu Asp Pro Lys Gly Ile 
225                 230                 235                 240 


Pro Asp Phe Trp Leu Thr Val Leu Lys Asn Val Asp Thr Leu Thr Pro 
                245                 250                 255     


Leu Ile Lys Lys Tyr Asp Glu Pro Ile Leu Lys Leu Leu Thr Asp Ile 
            260                 265                 270         


Lys Val Lys Leu Ser Asp Pro Gly Glu Pro Leu Ser Phe Thr Leu Glu 
        275                 280                 285             


Phe His Phe Lys Pro Asn Glu Tyr Phe Lys Asn Glu Leu Leu Thr Lys 
    290                 295                 300                 


Thr Tyr Val Leu Lys Ser Lys Leu Ala Tyr Tyr Asp Pro His Pro Tyr 
305                 310                 315                 320 


Arg Gly Thr Ala Ile Glu Tyr Ser Thr Gly Cys Glu Ile Asp Trp Asn 
                325                 330                 335     


Glu Gly Lys Asn Val Thr Leu Lys Thr Ile Lys Lys Lys Gln Lys His 
            340                 345                 350         


Arg Ile Trp Gly Thr Ile Arg Thr Val Thr Glu Asp Phe Pro Lys Asp 
        355                 360                 365             


Ser Phe Phe Asn Phe Phe Ser Pro His Gly Ile Thr Ser Asn Gly Arg 
    370                 375                 380                 


Asp Gly Asn Asp Asp Phe Leu Leu Gly His Asn Leu Arg Thr Tyr Ile 
385                 390                 395                 400 


Ile Pro Arg Ser Val Leu Phe Phe Ser Gly Asp Ala Leu Glu Ser Gln 
                405                 410                 415     


Gln Glu Gly Val Val Arg Glu Val Asn Asp Ala Ile Tyr Asp Lys Ile 
            420                 425                 430         


Ile Tyr Asp Asn Trp Met Ala Ala Ile Glu Glu Val Lys Ala Cys Cys 
        435                 440                 445             


Lys Asn Leu Glu Ala Leu Val Glu Asp Ile Asp Arg 
    450                 455                 460 


<210>  2697
<211>  596
<212>  PRT
<213>  homo sapiens

<400>  2697

Met Glu Pro Glu Leu Ala Ala Gln Lys Gln Pro Arg Pro Arg Arg Arg 
1               5                   10                  15      


Ser Arg Arg Ala Ser Gly Leu Ser Thr Glu Gly Ala Thr Gly Pro Ser 
            20                  25                  30          


Ala Asp Thr Ser Gly Ser Glu Leu Asp Gly Arg Cys Ser Leu Arg Arg 
        35                  40                  45              


Gly Ser Ser Phe Thr Phe Leu Thr Pro Gly Pro Asn Trp Asp Phe Thr 
    50                  55                  60                  


Leu Lys Arg Lys Arg Arg Glu Lys Asp Asp Asp Val Val Ser Leu Ser 
65                  70                  75                  80  


Ser Leu Asp Leu Lys Glu Pro Ser Asn Lys Arg Val Arg Pro Leu Ala 
                85                  90                  95      


Arg Val Thr Ser Leu Ala Asn Leu Ile Ser Pro Val Arg Asn Gly Ala 
            100                 105                 110         


Val Arg Arg Phe Gly Gln Thr Ile Gln Ser Phe Thr Leu Arg Gly Asp 
        115                 120                 125             


His Arg Ser Pro Ala Ser Ala Gln Lys Phe Ser Ser Arg Ser Thr Val 
    130                 135                 140                 


Pro Thr Pro Ala Lys Arg Arg Ser Ser Ala Leu Trp Ser Glu Met Leu 
145                 150                 155                 160 


Asp Ile Thr Met Lys Glu Ser Leu Thr Thr Arg Glu Ile Arg Arg Gln 
                165                 170                 175     


Glu Ala Ile Tyr Glu Met Ser Arg Gly Glu Gln Asp Leu Ile Glu Asp 
            180                 185                 190         


Leu Lys Leu Ala Arg Lys Ala Tyr His Asp Pro Met Leu Lys Leu Ser 
        195                 200                 205             


Ile Met Ser Glu Glu Glu Leu Thr His Ile Phe Gly Asp Leu Asp Ser 
    210                 215                 220                 


Tyr Ile Pro Leu His Glu Asp Leu Leu Thr Arg Ile Gly Glu Ala Thr 
225                 230                 235                 240 


Lys Pro Asp Gly Thr Val Glu Gln Ile Gly His Ile Leu Val Ser Trp 
                245                 250                 255     


Leu Pro Arg Leu Asn Ala Tyr Arg Gly Tyr Cys Ser Asn Gln Leu Ala 
            260                 265                 270         


Ala Lys Ala Leu Leu Asp Gln Lys Lys Gln Asp Pro Arg Val Gln Asp 
        275                 280                 285             


Phe Leu Gln Arg Cys Leu Glu Ser Pro Phe Ser Arg Lys Leu Asp Leu 
    290                 295                 300                 


Trp Ser Phe Leu Asp Ile Pro Arg Ser Arg Leu Val Lys Tyr Pro Leu 
305                 310                 315                 320 


Leu Leu Lys Glu Ile Leu Lys His Thr Pro Lys Glu His Pro Asp Val 
                325                 330                 335     


Gln Leu Leu Glu Asp Ala Ile Leu Ile Ile Gln Gly Val Leu Ser Asp 
            340                 345                 350         


Ile Asn Leu Lys Lys Gly Glu Ser Glu Cys Gln Tyr Tyr Ile Asp Lys 
        355                 360                 365             


Leu Glu Tyr Leu Asp Glu Lys Gln Arg Asp Pro Arg Ile Glu Ala Ser 
    370                 375                 380                 


Lys Val Leu Leu Cys His Gly Glu Leu Arg Ser Lys Ser Gly His Lys 
385                 390                 395                 400 


Leu Tyr Ile Phe Leu Phe Gln Asp Ile Leu Val Leu Thr Arg Pro Val 
                405                 410                 415     


Thr Arg Asn Glu Arg His Ser Tyr Gln Val Tyr Arg Gln Pro Ile Pro 
            420                 425                 430         


Val Gln Glu Leu Val Leu Glu Asp Leu Gln Asp Gly Asp Val Arg Met 
        435                 440                 445             


Gly Gly Ser Phe Arg Gly Ala Phe Ser Asn Ser Glu Lys Ala Lys Asn 
    450                 455                 460                 


Ile Phe Arg Ile Arg Phe His Asp Pro Ser Pro Ala Gln Ser His Thr 
465                 470                 475                 480 


Leu Gln Ala Asn Asp Val Phe His Lys Gln Gln Trp Phe Asn Cys Ile 
                485                 490                 495     


Arg Ala Ala Ile Ala Pro Phe Gln Ser Ala Gly Ser Pro Pro Glu Leu 
            500                 505                 510         


Gln Gly Leu Pro Glu Leu His Glu Glu Cys Glu Gly Asn His Pro Ser 
        515                 520                 525             


Ala Arg Lys Leu Thr Ala Gln Arg Arg Ala Ser Thr Val Ser Ser Val 
    530                 535                 540                 


Thr Gln Val Glu Val Asp Glu Asn Ala Tyr Arg Cys Gly Ser Gly Met 
545                 550                 555                 560 


Gln Met Ala Glu Asp Ser Lys Ser Leu Lys Thr His Gln Thr Gln Pro 
                565                 570                 575     


Gly Ile Arg Arg Ala Arg Asp Lys Ala Leu Ser Gly Gly Lys Arg Lys 
            580                 585                 590         


Glu Thr Leu Val 
        595     


<210>  2698
<211>  2430
<212>  PRT
<213>  homo sapiens

<400>  2698

Met Ala Pro Pro Ala His Lys Ser Ile Leu Glu Arg Ser Glu Asn Val 
1               5                   10                  15      


Leu Met Ser Pro Trp Lys Gly Lys Leu Ile Val Gln Asp Arg Met Leu 
            20                  25                  30          


Cys Asp Ile Ala Leu Trp Ser Thr Tyr Gly Ala Met Ile Pro Thr Gln 
        35                  40                  45              


Leu Pro Gln Glu Leu Asp Phe Lys Tyr Val Met Lys Val Ser Ser Leu 
    50                  55                  60                  


Lys Lys Arg Leu Pro Glu Ala Ala Phe Arg Lys Gln Asn Tyr Leu Glu 
65                  70                  75                  80  


Glu Lys Val Cys Phe Gln Asp Leu Cys Phe Asn Leu Tyr Glu Val Glu 
                85                  90                  95      


Leu Ser Asn Arg Gln Gly Glu Asn Ile Asp Lys Leu Thr Glu Cys Ile 
            100                 105                 110         


Lys Asn Lys Gln Leu Ala Ile Ile Lys Cys Leu Glu Asp Arg Gly Phe 
        115                 120                 125             


Phe Ile Leu Leu Thr Ser Ser Ala Leu Leu Ser Glu Pro Asp Phe Gly 
    130                 135                 140                 


Gly Lys Gln Met Gly Leu His Gly Leu His Leu Phe Arg Ser Pro Leu 
145                 150                 155                 160 


Ser Thr Gly Val Lys Asp Leu Lys Val Glu Asp Asp Ile Ser Met Lys 
                165                 170                 175     


Val Ile Pro Ile Leu Ser Thr Leu Asn Cys Ala Leu Leu Glu Thr Lys 
            180                 185                 190         


Lys Ser Leu Pro Glu Glu Arg Ile His Pro Asn Thr Leu Val Lys Arg 
        195                 200                 205             


His Phe Gln Glu Leu Tyr Lys Ala Asp Arg Ser Pro Ser Leu Ser Val 
    210                 215                 220                 


Ala Pro Gln Asp Arg Met Lys Asp Pro Thr Phe Leu Gly Lys Leu Pro 
225                 230                 235                 240 


Ser Gly Phe Asp Leu Ile Pro Pro Ala Glu Lys Cys Pro Ser Glu Ser 
                245                 250                 255     


Leu Thr Gln Leu Asn Ser Tyr Phe Ser Asp Pro Ser Ala Tyr Ile Leu 
            260                 265                 270         


Glu Val Ser Thr Ala Leu Asp Leu Leu Ala Glu His Pro Gln Ser Pro 
        275                 280                 285             


Cys Val Ser Asp Gly Ile Cys Asp Ala Gly Phe Ser Leu Val Met Thr 
    290                 295                 300                 


Pro Asp Pro Glu Phe Leu Val Ser Glu Ala Glu Val Arg Lys Glu Thr 
305                 310                 315                 320 


Glu Thr Lys Lys Asp Ser Glu Glu Met Leu Lys Ala Lys Lys Arg Val 
                325                 330                 335     


Phe Pro Leu Ser Pro Ala Ser Asn Leu Arg Val Gln Pro Lys Arg Lys 
            340                 345                 350         


Ala Ser Met Pro His Met Val Gln Ser Lys Lys Val Asn Leu Cys Arg 
        355                 360                 365             


Pro Phe Pro Lys Arg Thr Ala Ser Arg Ala Asp Asn Ser Ser Asp Ser 
    370                 375                 380                 


Pro Thr Thr Leu Lys Leu Val Lys Gly Gln Phe Pro Gln Lys Arg Lys 
385                 390                 395                 400 


Arg Gly Ala Glu Val Leu Thr Ala Gln Phe Val Gln Lys Thr Lys Leu 
                405                 410                 415     


Asp Arg Lys Asn Gln Glu Ala Pro Ile Ser Lys Asp Val Pro Val Pro 
            420                 425                 430         


Thr Asn Ala Lys Arg Ala Arg Lys Gln Glu Lys Ser Pro Val Lys Thr 
        435                 440                 445             


Val Pro Arg Ala Lys Pro Pro Val Lys Lys Ser Pro Gln Lys Gln Arg 
    450                 455                 460                 


Val Asn Ile Val Lys Gly Asn Glu Asn Pro Arg Asn Arg Lys Gln Leu 
465                 470                 475                 480 


Gln Pro Val Lys Gly Glu Thr Ala Ser Lys Leu Gln Ser Glu Ile Ser 
                485                 490                 495     


Arg Gly Cys Gln Glu Asp Gly Ile Ser Ile Asn Ser Val Gln Pro Glu 
            500                 505                 510         


Asn Thr Thr Ala Ala His Asn Asp Leu Pro Glu Asn Ser Ile Val Asn 
        515                 520                 525             


Tyr Asp Ser Gln Ala Leu Asn Met Leu Ala Asp Leu Ala Leu Ser Ser 
    530                 535                 540                 


Ala Thr Ser Ser Thr Pro Val Ser Glu Ala Arg Asn Leu His Cys Ser 
545                 550                 555                 560 


Ser Glu Leu Pro Gln Asn Asp Val Leu Leu Ser Lys Glu Asn Ser Leu 
                565                 570                 575     


Arg Gly Thr Ser Asp His Glu Tyr His Arg Gly Val Lys Thr Gln Lys 
            580                 585                 590         


Gly Glu Leu Leu Pro Asn Pro Ser Ser Asp Arg Lys Ser Asn Ser Gly 
        595                 600                 605             


Ser Asp Leu Thr Val Ser Gln Asp Glu Glu Ser Leu Val Pro Cys Ser 
    610                 615                 620                 


Gln Ala Pro Ala Lys Ala Gln Ser Ala Leu Thr Glu Glu Met Leu Glu 
625                 630                 635                 640 


Ser Ser Asp Ala Ser Gln Ser Ser Ser Val Ser Val Glu His Ser Tyr 
                645                 650                 655     


Ala Leu Leu Leu Thr Glu His Ser Lys Lys His Leu Gln Glu Arg Glu 
            660                 665                 670         


Ile Leu Ser Pro Leu Phe Pro Arg Asn Gly Thr Lys Ser Pro Glu Ala 
        675                 680                 685             


Ala Thr Pro Val Gly Lys Val Met Pro Phe Arg His Gln Pro Gly Leu 
    690                 695                 700                 


Leu Leu Gln Gln Lys Pro Pro Asp Asp Pro Val Val Lys Pro Lys Asp 
705                 710                 715                 720 


Arg Pro Pro Ser Ala Arg Val Lys Lys Ser Ser Cys Ser Arg Ile Val 
                725                 730                 735     


Leu Ser Cys Asp Asp Ser Val Lys Ile Thr Phe Lys Cys Glu Thr Glu 
            740                 745                 750         


Tyr Ala Phe Ser Leu Asp Ser Lys Tyr Thr Asn Asn Pro Leu Glu Lys 
        755                 760                 765             


Thr Val Val Arg Ala Leu His Gly Pro Trp Asn Thr Asp Leu Pro Asp 
    770                 775                 780                 


Asn Val Glu Glu Val Lys Leu Leu Leu His Met Trp Val Ala Leu Phe 
785                 790                 795                 800 


Tyr Ser Asn Gln Asn Lys Ile Ile Arg Ser Ser Arg Lys Val Val Glu 
                805                 810                 815     


His Ser Asn Pro Ala Lys Tyr Val Ser Ile Asn Ser Thr Leu Glu Ser 
            820                 825                 830         


Cys Glu Leu Arg Glu Ile Glu Glu Ser Leu Gly Leu Glu Lys Cys Ser 
        835                 840                 845             


Ala Asp Ser Leu Leu Glu Thr Asn Glu Ile Ser Arg Ala His Ala Ala 
    850                 855                 860                 


Glu Val Ser Phe Arg Asp Pro Asn Cys Leu Leu Pro Phe Ile Lys Thr 
865                 870                 875                 880 


Pro Leu Thr Gln Gly Leu Glu Leu Cys Val Gln Asn Glu Gln Lys Lys 
                885                 890                 895     


Thr Phe Ala Arg Glu Cys Asp Pro Asp Thr Gln Glu Asp Gln Asn Phe 
            900                 905                 910         


Ile Cys Ser Tyr Asn Asn Glu Val Thr Gly Glu Glu Ala Lys Gln Glu 
        915                 920                 925             


Ser Leu Glu Thr Ser Asn Leu Val Leu Ser Gly Ile Gly Ser Thr Gln 
    930                 935                 940                 


Thr Asn Gly Pro Ser Val Pro Ser Glu Glu Glu Ile Val Gln Pro Leu 
945                 950                 955                 960 


Asp Ser Thr Arg Val Ala Ser Tyr Ser Gly Thr Val Thr Gln Ala Thr 
                965                 970                 975     


Phe Thr Arg Thr Tyr Asp Gly Pro Gly Ser Gln Pro Val Ile Cys Gln 
            980                 985                 990         


Ser Ser Val Tyr Gly Thr Leu Glu  Asn Lys Val Asp Ile  Leu Asp Ala 
        995                 1000                 1005             


Ala Val  Gln Thr Lys Thr Gly  Thr Leu Gln Asp Leu  Ile Gln His 
    1010                 1015                 1020             


Gly Ser  Pro Ile Asn Asn Glu  Cys His Pro Ser Leu  Glu Arg Lys 
    1025                 1030                 1035             


Asp Asp  Asn Met Gly Cys Ala  Val Ile Asn Pro Glu  Pro Ile Thr 
    1040                 1045                 1050             


Leu Thr  Phe Glu Lys Asn Ala  His Val Pro Ile Gln  Thr Glu Gly 
    1055                 1060                 1065             


Val Asn  Thr Ala Asp Glu Arg  Thr Thr Phe Lys Lys  Glu Leu Ile 
    1070                 1075                 1080             


Lys Gln  Val Ser Pro Ala Ala  Ser Leu Arg His Pro  Val Ser Thr 
    1085                 1090                 1095             


Ser Glu  Asn Ala Arg Thr Gln  Gly Leu Arg Asp Ile  Pro Ser Leu 
    1100                 1105                 1110             


Val Val  Ala Gly Gln Lys Gly  Thr Lys Tyr Leu Cys  Ala Ser Ser 
    1115                 1120                 1125             


Val Gly  Gly Glu Thr Leu Asp  Lys Ala Val Cys Ser  Leu Gln Lys 
    1130                 1135                 1140             


Glu Thr  Pro Leu Pro Val Ser  Leu Pro Ser Asp Lys  Thr Met Val 
    1145                 1150                 1155             


Met Glu  Ala Leu Ser Leu Ala  Lys Ser Ser Ser His  Leu Ser Pro 
    1160                 1165                 1170             


Ser Glu  Glu Val Arg Cys Thr  Gln Asp Phe Leu Ser  Gln Thr Gln 
    1175                 1180                 1185             


Ser Leu  Leu Gly Leu Ser Ser  Glu Gly Leu Leu Glu  Leu Thr Gln 
    1190                 1195                 1200             


Val Glu  Val Asp Ser Ser Ser  Ala Ser Thr Thr Leu  Gly Arg Gln 
    1205                 1210                 1215             


Cys Ser  Leu Asn Cys Ile Ser  Ser Gly Cys His Thr  Ser Gly Asp 
    1220                 1225                 1230             


Ser Leu  Glu Leu Arg Lys Asn  His Lys Asn Gly Pro  Asn Thr Glu 
    1235                 1240                 1245             


Asn Met  Asn Leu Glu Ala Phe  Asp Ser Val Phe Ile  Lys Gln Thr 
    1250                 1255                 1260             


Ser Leu  Ser Val Ser Arg Glu  Val Ser Leu Glu Leu  Ser Glu Glu 
    1265                 1270                 1275             


Asp Ser  Asp Ile Asp Leu Ala  Leu Thr Ile Ser Pro  Pro Thr Ser 
    1280                 1285                 1290             


Pro Arg  Glu Glu Met Pro Ala  Gly Glu Ile Glu Gln  Phe Glu Glu 
    1295                 1300                 1305             


Ala Pro  Phe Ser Asn Leu Glu  Leu Gln Asp Val Ala  Glu Glu Ile 
    1310                 1315                 1320             


Gly Glu  Pro Glu Glu Val Ala  Leu Thr Glu Ser Arg  Glu Val Ser 
    1325                 1330                 1335             


Ser Ala  Asp Asn Val Ser Val  Tyr Pro Ser Val Ser  Glu Glu Pro 
    1340                 1345                 1350             


Val Glu  Asn Lys Glu Arg Lys  Gly Asp Asn Leu Gln  Pro Val Thr 
    1355                 1360                 1365             


Leu Ile  Leu Ser Lys Glu Asn  Cys Thr Leu Glu Ile  Ala Glu Glu 
    1370                 1375                 1380             


Ile Asn  Val Thr Ser Asp Phe  Pro Phe Asp Ser Val  Ile Glu Glu 
    1385                 1390                 1395             


Val Ser  Pro Ala Ser Ser Pro  Glu Pro Pro Val Pro  Val Lys Glu 
    1400                 1405                 1410             


Thr Arg  Pro Tyr Gln Ala Val  Thr Pro Cys Ile Leu  Lys Leu His 
    1415                 1420                 1425             


Gly Thr  Gln Cys Glu Lys Ser  Asn Gln Ile Ser Gln  Cys Glu Ser 
    1430                 1435                 1440             


Glu Asp  Leu Gly Ile Thr Glu  Lys Glu Asn Val Phe  Val Gly Pro 
    1445                 1450                 1455             


Thr His  Pro Val Gly Gln Asp  Asn Phe Thr Gln Val  Gln Gln Met 
    1460                 1465                 1470             


Gln Val  Ser Ala Glu Met Pro  Leu Ile Leu Thr Asp  His Pro Gly 
    1475                 1480                 1485             


Arg Thr  Gly Arg Pro Thr Leu  Pro Gly Lys Val Thr  Glu Glu Ile 
    1490                 1495                 1500             


Val Ser  Ser Glu His Asp Glu  Gly Leu Ser Phe Ser  Gly Lys Val 
    1505                 1510                 1515             


Gln Cys  Tyr Gly Arg Glu Leu  Asn Gln Pro Ala Ser  Ala Ala Lys 
    1520                 1525                 1530             


Cys Thr  Gly Asp Phe Ser Pro  Ser Pro Glu Lys Leu  Val Lys Ser 
    1535                 1540                 1545             


Gly Asn  Pro Leu Gln Pro Val  Ser Ile Glu Asn Arg  Asn Leu Asp 
    1550                 1555                 1560             


Leu Lys  His Leu Val Leu Glu  Ser Ser Glu Pro Pro  Phe Gly Pro 
    1565                 1570                 1575             


Arg Asn  Val Ile Glu Asn Lys  Ser Leu Ser Asp Thr  Leu Val Ser 
    1580                 1585                 1590             


Thr Thr  Ala Pro Ser Gly Ile  Val Asn Val Ser Val  Lys Gln Gln 
    1595                 1600                 1605             


Thr Ser  Pro Lys Ser Ser Gln  Asn His Leu Phe Pro  Gly Asp Leu 
    1610                 1615                 1620             


Lys Thr  Asp Glu Gly Ile Tyr  Leu Gln Val Lys Ser  Leu Thr Ala 
    1625                 1630                 1635             


Ala Ser  Val Asp Gly Ala Tyr  Ser Thr Gln Gly Cys  Met Cys Ser 
    1640                 1645                 1650             


Val Val  Pro Thr Leu Cys Ser  Ser Ser Asp Asn Ala  Thr Leu Thr 
    1655                 1660                 1665             


His Tyr  Val Arg Pro Ile Asn  Ala Glu Pro Ala Phe  Gln Ala Gln 
    1670                 1675                 1680             


Glu Ile  Pro Ala Gly Arg Met  Ala Ser Leu Leu Lys  Asn Gly Glu 
    1685                 1690                 1695             


Pro Glu  Ala Glu Leu His Lys  Glu Thr Thr Gly Pro  Gly Thr Ala 
    1700                 1705                 1710             


Gly Pro  Gln Ser Asn Thr Thr  Ser Ser Leu Lys Gly  Glu Arg Lys 
    1715                 1720                 1725             


Ala Ile  His Thr Leu Gln Asp  Val Ser Thr Cys Glu  Thr Lys Glu 
    1730                 1735                 1740             


Leu Leu  Asn Val Gly Val Ser  Ser Leu Cys Ala Gly  Pro Tyr Gln 
    1745                 1750                 1755             


Asn Thr  Ala Asp Thr Lys Glu  Asn Leu Ser Lys Glu  Pro Leu Ala 
    1760                 1765                 1770             


Ser Phe  Val Ser Glu Ser Phe  Asp Thr Ser Val Cys  Gly Ile Ala 
    1775                 1780                 1785             


Thr Glu  His Val Glu Ile Glu  Asn Ser Gly Glu Gly  Leu Arg Ala 
    1790                 1795                 1800             


Glu Ala  Gly Ser Glu Thr Leu  Gly Arg Asp Gly Glu  Val Gly Val 
    1805                 1810                 1815             


Asn Ser  Asp Met His Tyr Glu  Leu Ser Gly Asp Ser  Asp Leu Asp 
    1820                 1825                 1830             


Leu Leu  Gly Asp Cys Arg Asn  Pro Arg Leu Asp Leu  Glu Asp Ser 
    1835                 1840                 1845             


Tyr Thr  Leu Arg Gly Ser Tyr  Thr Arg Lys Lys Asp  Val Pro Thr 
    1850                 1855                 1860             


Asp Gly  Tyr Glu Ser Ser Leu  Asn Phe His Asn Asn  Asn Gln Glu 
    1865                 1870                 1875             


Asp Trp  Gly Cys Ser Ser Trp  Val Pro Gly Met Glu  Thr Ser Leu 
    1880                 1885                 1890             


Pro Pro  Gly His Trp Thr Ala  Ala Val Lys Lys Glu  Glu Lys Cys 
    1895                 1900                 1905             


Val Pro  Pro Tyr Val Gln Ile  Arg Asp Leu His Gly  Ile Leu Arg 
    1910                 1915                 1920             


Thr Tyr  Ala Asn Phe Ser Ile  Thr Lys Glu Leu Lys  Asp Thr Met 
    1925                 1930                 1935             


Arg Thr  Ser His Gly Leu Arg  Arg His Pro Ser Phe  Ser Ala Asn 
    1940                 1945                 1950             


Cys Gly  Leu Pro Ser Ser Trp  Thr Ser Thr Trp Gln  Val Ala Asp 
    1955                 1960                 1965             


Asp Leu  Thr Gln Asn Thr Leu  Asp Leu Glu Tyr Leu  Arg Phe Ala 
    1970                 1975                 1980             


His Lys  Leu Lys Gln Thr Ile  Lys Asn Gly Asp Ser  Gln His Ser 
    1985                 1990                 1995             


Ala Ser  Ser Ala Asn Val Phe  Pro Lys Glu Ser Pro  Thr Gln Ile 
    2000                 2005                 2010             


Ser Ile  Gly Ala Phe Pro Ser  Thr Lys Ile Ser Glu  Ala Pro Phe 
    2015                 2020                 2025             


Leu His  Pro Ala Pro Arg Ser  Arg Ser Pro Leu Leu  Val Thr Val 
    2030                 2035                 2040             


Val Glu  Ser Asp Pro Arg Pro  Gln Gly Gln Pro Arg  Arg Gly Tyr 
    2045                 2050                 2055             


Thr Ala  Ser Ser Leu Asp Ser  Ser Ser Ser Trp Arg  Glu Arg Cys 
    2060                 2065                 2070             


Ser His  Asn Arg Asp Leu Arg  Asn Ser Gln Arg Asn  His Thr Val 
    2075                 2080                 2085             


Ser Phe  His Leu Asn Lys Leu  Lys Tyr Asn Ser Thr  Val Lys Glu 
    2090                 2095                 2100             


Ser Arg  Asn Asp Ile Ser Leu  Ile Leu Asn Glu Tyr  Ala Glu Phe 
    2105                 2110                 2115             


Asn Lys  Val Met Lys Asn Ser  Asn Gln Phe Ile Phe  Gln Asp Lys 
    2120                 2125                 2130             


Glu Leu  Asn Asp Val Ser Gly  Glu Ala Thr Ala Gln  Glu Met Tyr 
    2135                 2140                 2145             


Leu Pro  Phe Pro Gly Arg Ser  Ala Ser Tyr Glu Asp  Ile Ile Ile 
    2150                 2155                 2160             


Asp Val  Cys Thr Asn Leu His  Val Lys Leu Arg Ser  Val Val Lys 
    2165                 2170                 2175             


Glu Ala  Cys Lys Ser Thr Phe  Leu Phe Tyr Leu Val  Glu Thr Glu 
    2180                 2185                 2190             


Asp Lys  Ser Phe Phe Val Arg  Thr Lys Asn Leu Leu  Arg Lys Gly 
    2195                 2200                 2205             


Gly His  Thr Glu Ile Glu Pro  Gln His Phe Cys Gln  Ala Phe His 
    2210                 2215                 2220             


Arg Glu  Asn Asp Thr Leu Ile  Ile Ile Ile Arg Asn  Glu Asp Ile 
    2225                 2230                 2235             


Ser Ser  His Leu His Gln Ile  Pro Ser Leu Leu Lys  Leu Lys His 
    2240                 2245                 2250             


Phe Pro  Ser Val Ile Phe Ala  Gly Val Asp Ser Pro  Gly Asp Val 
    2255                 2260                 2265             


Leu Asp  His Thr Tyr Gln Glu  Leu Phe Arg Ala Gly  Gly Phe Val 
    2270                 2275                 2280             


Ile Ser  Asp Asp Lys Ile Leu  Glu Ala Val Thr Leu  Val Gln Leu 
    2285                 2290                 2295             


Lys Glu  Ile Ile Lys Ile Leu  Glu Lys Leu Asn Gly  Asn Gly Arg 
    2300                 2305                 2310             


Trp Lys  Trp Leu Leu His Tyr  Arg Glu Asn Lys Lys  Leu Lys Glu 
    2315                 2320                 2325             


Asp Glu  Arg Val Asp Ser Thr  Ala His Lys Lys Asn  Ile Met Leu 
    2330                 2335                 2340             


Lys Ser  Phe Gln Ser Ala Asn  Ile Ile Glu Leu Leu  His Tyr His 
    2345                 2350                 2355             


Gln Cys  Asp Ser Arg Ser Ser  Thr Lys Ala Glu Ile  Leu Lys Cys 
    2360                 2365                 2370             


Leu Leu  Asn Leu Gln Ile Gln  His Ile Asp Ala Arg  Phe Ala Val 
    2375                 2380                 2385             


Leu Leu  Thr Asp Lys Pro Thr  Ile Pro Arg Glu Val  Phe Glu Asn 
    2390                 2395                 2400             


Ser Gly  Ile Leu Val Thr Asp  Val Asn Asn Phe Ile  Glu Asn Ile 
    2405                 2410                 2415             


Glu Lys  Ile Ala Ala Pro Phe  Arg Ser Ser Tyr Trp  
    2420                 2425                 2430 


<210>  2699
<211>  632
<212>  PRT
<213>  homo sapiens

<400>  2699

Met Glu Glu Leu Val Val Glu Val Arg Gly Ser Asn Gly Ala Phe Tyr 
1               5                   10                  15      


Lys Ala Phe Val Lys Asp Val His Glu Asp Ser Ile Thr Val Ala Phe 
            20                  25                  30          


Glu Asn Asn Trp Gln Pro Asp Arg Gln Ile Pro Phe His Asp Val Arg 
        35                  40                  45              


Phe Pro Pro Pro Val Gly Tyr Asn Lys Asp Ile Asn Glu Ser Asp Glu 
    50                  55                  60                  


Val Glu Val Tyr Ser Arg Ala Asn Glu Lys Glu Pro Cys Cys Trp Trp 
65                  70                  75                  80  


Leu Ala Lys Val Arg Met Ile Lys Gly Glu Phe Tyr Val Ile Glu Tyr 
                85                  90                  95      


Ala Ala Cys Asp Ala Thr Tyr Asn Glu Ile Val Thr Ile Glu Arg Leu 
            100                 105                 110         


Arg Ser Val Asn Pro Asn Lys Pro Ala Thr Lys Asp Thr Phe His Lys 
        115                 120                 125             


Ile Lys Leu Asp Val Pro Glu Asp Leu Arg Gln Met Cys Ala Lys Glu 
    130                 135                 140                 


Ala Ala His Lys Asp Phe Lys Lys Ala Val Gly Ala Phe Ser Val Thr 
145                 150                 155                 160 


Tyr Asp Pro Glu Asn Tyr Gln Leu Val Ile Leu Ser Ile Asn Glu Val 
                165                 170                 175     


Thr Ser Lys Arg Ala His Met Leu Ile Asp Met His Phe Arg Ser Leu 
            180                 185                 190         


Arg Thr Lys Leu Ser Leu Ile Met Arg Asn Glu Glu Ala Ser Lys Gln 
        195                 200                 205             


Leu Glu Ser Ser Arg Gln Leu Ala Ser Arg Phe His Glu Gln Phe Ile 
    210                 215                 220                 


Val Arg Glu Asp Leu Met Gly Leu Ala Ile Gly Thr His Gly Ala Asn 
225                 230                 235                 240 


Ile Gln Gln Ala Arg Lys Val Pro Gly Val Thr Ala Ile Asp Leu Asp 
                245                 250                 255     


Glu Asp Thr Cys Thr Phe His Ile Tyr Gly Glu Asp Gln Asp Ala Val 
            260                 265                 270         


Lys Lys Ala Arg Ser Phe Leu Glu Phe Ala Glu Asp Val Ile Gln Val 
        275                 280                 285             


Pro Arg Asn Leu Val Gly Lys Val Ile Gly Lys Asn Gly Lys Leu Ile 
    290                 295                 300                 


Gln Glu Ile Val Asp Lys Ser Gly Val Val Arg Val Arg Ile Glu Ala 
305                 310                 315                 320 


Glu Asn Glu Lys Asn Val Pro Gln Glu Glu Glu Ile Met Pro Pro Asn 
                325                 330                 335     


Ser Leu Pro Ser Asn Asn Ser Arg Val Gly Pro Asn Ala Pro Glu Glu 
            340                 345                 350         


Lys Lys His Leu Asp Ile Lys Glu Asn Ser Thr His Phe Ser Gln Pro 
        355                 360                 365             


Asn Ser Thr Lys Val Gln Arg Val Leu Val Ala Ser Ser Val Val Ala 
    370                 375                 380                 


Gly Glu Ser Gln Lys Pro Glu Leu Lys Ala Trp Gln Gly Met Val Pro 
385                 390                 395                 400 


Phe Val Phe Val Gly Thr Lys Asp Ser Ile Ala Asn Ala Thr Val Leu 
                405                 410                 415     


Leu Asp Tyr His Leu Asn Tyr Leu Lys Glu Val Asp Gln Leu Arg Leu 
            420                 425                 430         


Glu Arg Leu Gln Ile Asp Glu Gln Leu Arg Gln Ile Gly Ala Ser Ser 
        435                 440                 445             


Arg Pro Pro Pro Asn Arg Thr Asp Lys Glu Lys Ser Tyr Val Thr Asp 
    450                 455                 460                 


Asp Gly Gln Gly Met Gly Arg Gly Ser Arg Pro Tyr Arg Asn Arg Gly 
465                 470                 475                 480 


His Gly Arg Arg Gly Pro Gly Tyr Thr Ser Gly Thr Asn Ser Glu Ala 
                485                 490                 495     


Ser Asn Ala Ser Glu Thr Glu Ser Asp His Arg Asp Glu Leu Ser Asp 
            500                 505                 510         


Trp Ser Leu Ala Pro Thr Glu Glu Glu Arg Glu Ser Phe Leu Arg Arg 
        515                 520                 525             


Gly Asp Gly Arg Arg Arg Gly Gly Gly Gly Arg Gly Gln Gly Gly Arg 
    530                 535                 540                 


Gly Arg Gly Gly Gly Phe Lys Gly Asn Asp Asp His Ser Arg Thr Asp 
545                 550                 555                 560 


Asn Arg Pro Arg Asn Pro Arg Glu Ala Lys Gly Arg Thr Thr Asp Gly 
                565                 570                 575     


Ser Leu Gln Ile Arg Val Asp Cys Asn Asn Glu Arg Ser Val His Thr 
            580                 585                 590         


Lys Thr Leu Gln Asn Thr Ser Ser Glu Gly Ser Arg Leu Arg Thr Gly 
        595                 600                 605             


Lys Asp Arg Asn Gln Lys Lys Glu Lys Pro Asp Ser Val Asp Gly Gln 
    610                 615                 620                 


Gln Pro Leu Val Asn Gly Val Pro 
625                 630         


<210>  2700
<211>  483
<212>  PRT
<213>  homo sapiens

<400>  2700

Met Lys Arg His Glu Met Val Ala Lys His Leu Val Met Phe Tyr Tyr 
1               5                   10                  15      


Phe Ala Gln His Leu Trp Pro Glu Gln Asn Ile Arg Asp Ser Phe Gln 
            20                  25                  30          


Lys Val Thr Leu Arg Arg Tyr Arg Lys Cys Gly Tyr Glu Asn Leu Gln 
        35                  40                  45              


Leu Arg Lys Gly Cys Lys Ser Val Val Glu Cys Lys Gln His Lys Gly 
    50                  55                  60                  


Asp Tyr Ser Gly Leu Asn Gln Cys Leu Lys Thr Thr Leu Ser Lys Ile 
65                  70                  75                  80  


Phe Gln Cys Asn Lys Tyr Val Glu Val Phe His Lys Ile Ser Asn Ser 
                85                  90                  95      


Asn Arg His Lys Met Arg His Thr Glu Asn Lys His Phe Lys Cys Lys 
            100                 105                 110         


Glu Cys Arg Lys Thr Phe Cys Met Leu Ser His Leu Thr Gln His Lys 
        115                 120                 125             


Arg Ile Gln Thr Arg Val Asn Phe Tyr Lys Cys Glu Ala Tyr Gly Arg 
    130                 135                 140                 


Ala Phe Asn Trp Ser Ser Thr Leu Asn Lys His Lys Arg Ile His Thr 
145                 150                 155                 160 


Gly Glu Lys Pro Tyr Lys Cys Lys Glu Cys Gly Lys Ala Phe Asn Gln 
                165                 170                 175     


Thr Ser His Leu Ile Arg His Lys Arg Ile His Thr Glu Glu Lys Pro 
            180                 185                 190         


Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Gln Ser Ser Thr Leu 
        195                 200                 205             


Thr Thr His Asn Ile Ile His Thr Gly Glu Ile Pro Tyr Lys Cys Glu 
    210                 215                 220                 


Lys Cys Val Arg Ala Phe Asn Gln Ala Ser Lys Leu Thr Glu His Lys 
225                 230                 235                 240 


Leu Ile His Thr Gly Glu Lys Arg Tyr Glu Cys Glu Glu Cys Gly Lys 
                245                 250                 255     


Ala Phe Asn Arg Ser Ser Lys Leu Thr Glu His Lys Tyr Ile His Thr 
            260                 265                 270         


Gly Glu Lys Leu Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Gln 
        275                 280                 285             


Ser Ser Thr Leu Thr Thr His Lys Arg Ile His Ser Gly Glu Lys Pro 
    290                 295                 300                 


Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Lys Gln Phe Ser Asn Leu 
305                 310                 315                 320 


Thr Asp His Lys Lys Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Glu 
                325                 330                 335     


Glu Cys Gly Lys Ala Phe Asn Gln Leu Ser Asn Leu Thr Arg His Lys 
            340                 345                 350         


Val Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Gly Glu Cys Gly Lys 
        355                 360                 365             


Ala Phe Asn Gln Ser Ser Ala Leu Asn Thr His Lys Ile Ile His Thr 
    370                 375                 380                 


Gly Glu Asn Pro His Lys Cys Arg Glu Ser Gly Lys Val Phe His Leu 
385                 390                 395                 400 


Ser Ser Lys Leu Ser Thr Cys Lys Lys Ile His Thr Gly Glu Lys Leu 
                405                 410                 415     


Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Arg Ser Ser Thr Leu 
            420                 425                 430         


Ile Gly His Lys Arg Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Glu 
        435                 440                 445             


Glu Cys Gly Lys Ala Phe Asn Gln Ser Ser Thr Leu Thr Thr His Lys 
    450                 455                 460                 


Ile Ile His Thr Glu Glu Lys Gln Tyr Lys Cys Asp Glu Cys Gly Lys 
465                 470                 475                 480 


Ala Ser Thr 
            


<210>  2701
<211>  1153
<212>  PRT
<213>  homo sapiens

<400>  2701

Met Ala Cys Pro Trp Lys Phe Leu Phe Lys Thr Lys Phe His Gln Tyr 
1               5                   10                  15      


Ala Met Asn Gly Glu Lys Asp Ile Asn Asn Asn Val Glu Lys Ala Pro 
            20                  25                  30          


Cys Ala Thr Ser Ser Pro Val Thr Gln Asp Asp Leu Gln Tyr His Asn 
        35                  40                  45              


Leu Ser Lys Gln Gln Asn Glu Ser Pro Gln Pro Leu Val Glu Thr Gly 
    50                  55                  60                  


Lys Lys Ser Pro Glu Ser Leu Val Lys Leu Asp Ala Thr Pro Leu Ser 
65                  70                  75                  80  


Ser Pro Arg His Val Arg Ile Lys Asn Trp Gly Ser Gly Met Thr Phe 
                85                  90                  95      


Gln Asp Thr Leu His His Lys Ala Lys Gly Ile Leu Thr Cys Arg Ser 
            100                 105                 110         


Lys Ser Cys Leu Gly Ser Ile Met Thr Pro Lys Ser Leu Thr Arg Gly 
        115                 120                 125             


Pro Arg Asp Lys Pro Thr Pro Pro Asp Glu Leu Leu Pro Gln Ala Ile 
    130                 135                 140                 


Glu Phe Val Asn Gln Tyr Tyr Gly Ser Phe Lys Glu Ala Lys Ile Glu 
145                 150                 155                 160 


Glu His Leu Ala Arg Val Glu Ala Val Thr Lys Glu Ile Glu Thr Thr 
                165                 170                 175     


Gly Thr Tyr Gln Leu Thr Gly Asp Glu Leu Ile Phe Ala Thr Lys Gln 
            180                 185                 190         


Ala Trp Arg Asn Ala Pro Arg Cys Ile Gly Arg Ile Gln Trp Ser Asn 
        195                 200                 205             


Leu Gln Val Phe Asp Ala Arg Ser Cys Ser Thr Ala Arg Glu Met Phe 
    210                 215                 220                 


Glu His Ile Cys Arg His Val Arg Tyr Ser Thr Asn Asn Gly Asn Ile 
225                 230                 235                 240 


Arg Ser Ala Ile Thr Val Phe Pro Gln Arg Ser Asp Gly Lys His Asp 
                245                 250                 255     


Phe Arg Val Trp Asn Ala Gln Leu Ile Arg Tyr Ala Gly Tyr Gln Met 
            260                 265                 270         


Pro Asp Gly Ser Ile Arg Gly Asp Pro Ala Asn Val Glu Phe Thr Gln 
        275                 280                 285             


Leu Cys Ile Asp Leu Gly Trp Lys Pro Lys Tyr Gly Arg Phe Asp Val 
    290                 295                 300                 


Val Pro Leu Val Leu Gln Ala Asn Gly Arg Asp Pro Glu Leu Phe Glu 
305                 310                 315                 320 


Ile Pro Pro Asp Leu Val Leu Glu Val Ala Met Glu His Pro Lys Tyr 
                325                 330                 335     


Glu Trp Phe Arg Glu Leu Glu Leu Lys Trp Tyr Ala Leu Pro Ala Val 
            340                 345                 350         


Ala Asn Met Leu Leu Glu Val Gly Gly Leu Glu Phe Pro Gly Cys Pro 
        355                 360                 365             


Phe Asn Gly Trp Tyr Met Gly Thr Glu Ile Gly Val Arg Asp Phe Cys 
    370                 375                 380                 


Asp Val Gln Arg Tyr Asn Ile Leu Glu Glu Val Gly Arg Arg Met Gly 
385                 390                 395                 400 


Leu Glu Thr His Lys Leu Ala Ser Leu Trp Lys Asp Gln Ala Val Val 
                405                 410                 415     


Glu Ile Asn Ile Ala Val Leu His Ser Phe Gln Lys Gln Asn Val Thr 
            420                 425                 430         


Ile Met Asp His His Ser Ala Ala Glu Ser Phe Met Lys Tyr Met Gln 
        435                 440                 445             


Asn Glu Tyr Arg Ser Arg Gly Gly Cys Pro Ala Asp Trp Ile Trp Leu 
    450                 455                 460                 


Val Pro Pro Met Ser Gly Ser Ile Thr Pro Val Phe His Gln Glu Met 
465                 470                 475                 480 


Leu Asn Tyr Val Leu Ser Pro Phe Tyr Tyr Tyr Gln Val Glu Ala Trp 
                485                 490                 495     


Lys Thr His Val Trp Gln Asp Glu Lys Arg Arg Pro Lys Arg Arg Glu 
            500                 505                 510         


Ile Pro Leu Lys Val Leu Val Lys Ala Val Leu Phe Ala Cys Met Leu 
        515                 520                 525             


Met Arg Lys Thr Met Ala Ser Arg Val Arg Val Thr Ile Leu Phe Ala 
    530                 535                 540                 


Thr Glu Thr Gly Lys Ser Glu Ala Leu Ala Trp Asp Leu Gly Ala Leu 
545                 550                 555                 560 


Phe Ser Cys Ala Phe Asn Pro Lys Val Val Cys Met Asp Lys Tyr Arg 
                565                 570                 575     


Leu Ser Cys Leu Glu Glu Glu Arg Leu Leu Leu Val Val Thr Ser Thr 
            580                 585                 590         


Phe Gly Asn Gly Asp Cys Pro Gly Asn Gly Glu Lys Leu Lys Lys Ser 
        595                 600                 605             


Leu Phe Met Leu Lys Glu Leu Asn Asn Lys Phe Arg Tyr Ala Val Phe 
    610                 615                 620                 


Gly Leu Gly Ser Ser Met Tyr Pro Arg Phe Cys Ala Phe Ala His Asp 
625                 630                 635                 640 


Ile Asp Gln Lys Leu Ser His Leu Gly Ala Ser Gln Leu Thr Pro Met 
                645                 650                 655     


Gly Glu Gly Asp Glu Leu Ser Gly Gln Glu Asp Ala Phe Arg Ser Trp 
            660                 665                 670         


Ala Val Gln Thr Phe Lys Ala Ala Cys Glu Thr Phe Asp Val Arg Gly 
        675                 680                 685             


Lys Gln His Ile Gln Ile Pro Lys Leu Tyr Thr Ser Asn Val Thr Trp 
    690                 695                 700                 


Asp Pro His His Tyr Arg Leu Val Gln Asp Ser Gln Pro Leu Asp Leu 
705                 710                 715                 720 


Ser Lys Ala Leu Ser Ser Met His Ala Lys Asn Val Phe Thr Met Arg 
                725                 730                 735     


Leu Lys Ser Arg Gln Asn Leu Gln Ser Pro Thr Ser Ser Arg Ala Thr 
            740                 745                 750         


Ile Leu Val Glu Leu Ser Cys Glu Asp Gly Gln Gly Leu Asn Tyr Leu 
        755                 760                 765             


Pro Gly Glu His Leu Gly Val Cys Pro Gly Asn Gln Pro Ala Leu Val 
    770                 775                 780                 


Gln Gly Ile Leu Glu Arg Val Val Asp Gly Pro Thr Pro His Gln Thr 
785                 790                 795                 800 


Val Arg Leu Glu Ala Leu Asp Glu Ser Gly Ser Tyr Trp Val Ser Asp 
                805                 810                 815     


Lys Arg Leu Pro Pro Cys Ser Leu Ser Gln Ala Leu Thr Tyr Phe Leu 
            820                 825                 830         


Asp Ile Thr Thr Pro Pro Thr Gln Leu Leu Leu Gln Lys Leu Ala Gln 
        835                 840                 845             


Val Ala Thr Glu Glu Pro Glu Arg Gln Arg Leu Glu Ala Leu Cys Gln 
    850                 855                 860                 


Pro Ser Glu Tyr Ser Lys Trp Lys Phe Thr Asn Ser Pro Thr Phe Leu 
865                 870                 875                 880 


Glu Val Leu Glu Glu Phe Pro Ser Leu Arg Val Ser Ala Gly Phe Leu 
                885                 890                 895     


Leu Ser Gln Leu Pro Ile Leu Lys Pro Arg Phe Tyr Ser Ile Ser Ser 
            900                 905                 910         


Ser Arg Asp His Thr Pro Thr Glu Ile His Leu Thr Val Ala Val Val 
        915                 920                 925             


Thr Tyr His Thr Arg Asp Gly Gln Gly Pro Leu His His Gly Val Cys 
    930                 935                 940                 


Ser Thr Trp Leu Asn Ser Leu Lys Pro Gln Asp Pro Val Pro Cys Phe 
945                 950                 955                 960 


Val Arg Asn Ala Ser Gly Phe His Leu Pro Glu Asp Pro Ser His Pro 
                965                 970                 975     


Cys Ile Leu Ile Gly Pro Gly Thr Gly Ile Ala Pro Phe Arg Ser Phe 
            980                 985                 990         


Trp Gln Gln Arg Leu His Asp Ser  Gln His Lys Gly Val  Arg Gly Gly 
        995                 1000                 1005             


Arg Met  Thr Leu Val Phe Gly  Cys Arg Arg Pro Asp  Glu Asp His 
    1010                 1015                 1020             


Ile Tyr  Gln Glu Glu Met Leu  Glu Met Ala Gln Lys  Gly Val Leu 
    1025                 1030                 1035             


His Ala  Val His Thr Ala Tyr  Ser Arg Leu Pro Gly  Lys Pro Lys 
    1040                 1045                 1050             


Val Tyr  Val Gln Asp Ile Leu  Arg Gln Gln Leu Ala  Ser Glu Val 
    1055                 1060                 1065             


Leu Arg  Val Leu His Lys Glu  Pro Gly His Leu Tyr  Val Cys Gly 
    1070                 1075                 1080             


Asp Val  Arg Met Ala Arg Asp  Val Ala His Thr Leu  Lys Gln Leu 
    1085                 1090                 1095             


Val Ala  Ala Lys Leu Lys Leu  Asn Glu Glu Gln Val  Glu Asp Tyr 
    1100                 1105                 1110             


Phe Phe  Gln Leu Lys Ser Gln  Lys Arg Tyr His Glu  Asp Ile Phe 
    1115                 1120                 1125             


Gly Ala  Val Phe Pro Tyr Glu  Ala Lys Lys Asp Arg  Val Ala Val 
    1130                 1135                 1140             


Gln Pro  Ser Ser Leu Glu Met  Ser Ala Leu 
    1145                 1150             


<210>  2702
<211>  655
<212>  PRT
<213>  homo sapiens

<400>  2702

Met Ser Ala Leu Leu Gln Asp Pro Met Ile Ala Gly Gln Val Ser Lys 
1               5                   10                  15      


Pro Leu Leu Ser Val Arg Ser Glu Met Asn Ala Glu Leu Arg Gly Glu 
            20                  25                  30          


Asp Lys Ala Ala Thr Ser Asp Ser Glu Leu Asn Glu Pro Leu Leu Ala 
        35                  40                  45              


Pro Val Glu Ser Asn Asp Ser Glu Asp Thr Pro Ser Lys Leu Phe Gly 
    50                  55                  60                  


Ala Arg Gly Asn Pro Ala Leu Ser Asp Pro Gly Thr Pro Asp Gln His 
65                  70                  75                  80  


Gln Ala Ser Gln Thr His Pro Pro Phe Pro Val Gly Pro Gln Pro Leu 
                85                  90                  95      


Leu Thr Ala Gln Gln Leu Ala Ser Ala Val Ala Gly Val Met Pro Gly 
            100                 105                 110         


Gly Pro Pro Ala Leu Asn Gln Pro Ile Leu Ile Pro Phe Asn Met Ala 
        115                 120                 125             


Gly Gln Leu Gly Gly Gln Gln Gly Leu Val Leu Thr Leu Pro Thr Ala 
    130                 135                 140                 


Asn Leu Thr Asn Ile Gln Gly Leu Val Ala Ala Ala Ala Ala Gly Gly 
145                 150                 155                 160 


Ile Met Thr Leu Pro Leu Gln Asn Leu Gln Ala Thr Ser Ser Leu Asn 
                165                 170                 175     


Ser Gln Leu Gln Gln Leu Gln Leu Gln Leu Gln Gln Gln Gln Gln Gln 
            180                 185                 190         


Gln Gln Gln Gln Pro Pro Pro Ser Thr Asn Gln His Pro Gln Pro Ala 
        195                 200                 205             


Pro Gln Ala Pro Ser Gln Ser Gln Gln Gln Pro Leu Gln Pro Thr Pro 
    210                 215                 220                 


Pro Gln Gln Pro Pro Pro Ala Ser Gln Gln Pro Pro Ala Pro Thr Ser 
225                 230                 235                 240 


Gln Leu Gln Gln Ala Pro Gln Pro Gln Gln His Gln Pro His Ser His 
                245                 250                 255     


Ser Gln Asn Gln Asn Gln Pro Ser Pro Thr Gln Gln Ser Ser Ser Pro 
            260                 265                 270         


Pro Gln Lys Pro Ser Gln Ser Pro Gly His Gly Leu Pro Ser Pro Leu 
        275                 280                 285             


Thr Pro Pro Asn Pro Leu Gln Leu Val Asn Asn Pro Leu Ala Ser Gln 
    290                 295                 300                 


Ala Ala Ala Ala Ala Ala Ala Met Ser Ser Ile Ala Ser Ser Gln Ala 
305                 310                 315                 320 


Phe Gly Asn Ala Leu Ser Ser Leu Gln Gly Val Thr Gly Gln Leu Val 
                325                 330                 335     


Thr Asn Ala Gln Gly Gln Ile Ile Gly Thr Ile Pro Leu Met Pro Asn 
            340                 345                 350         


Pro Gly Pro Ser Ser Gln Ala Ala Ser Gly Thr Gln Gly Leu Gln Val 
        355                 360                 365             


Gln Pro Ile Thr Pro Gln Leu Leu Thr Asn Ala Gln Gly Gln Ile Ile 
    370                 375                 380                 


Ala Thr Val Ile Gly Asn Gln Ile Leu Pro Val Ile Asn Thr Gln Gly 
385                 390                 395                 400 


Ile Thr Leu Ser Pro Ile Lys Pro Gly Gln Gln Leu His Gln Pro Ser 
                405                 410                 415     


Gln Thr Ser Val Gly Gln Ala Ala Ser Gln Gly Asn Leu Leu His Leu 
            420                 425                 430         


Ala His Ser Gln Ala Ser Met Ser Gln Ser Pro Val Arg Gln Ala Ser 
        435                 440                 445             


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ala Leu Ser Val Gly Gln 
    450                 455                 460                 


Leu Val Ser Asn Pro Gln Thr Ala Ala Gly Glu Val Asp Gly Val Asn 
465                 470                 475                 480 


Leu Glu Glu Ile Arg Glu Phe Ala Lys Ala Phe Lys Ile Arg Arg Leu 
                485                 490                 495     


Ser Leu Gly Leu Thr Gln Thr Gln Val Gly Gln Ala Leu Ser Ala Thr 
            500                 505                 510         


Glu Gly Pro Ala Tyr Ser Gln Ser Ala Ile Cys Arg Phe Glu Lys Leu 
        515                 520                 525             


Asp Ile Thr Pro Lys Ser Ala Gln Lys Ile Lys Pro Val Leu Glu Arg 
    530                 535                 540                 


Trp Met Ala Glu Ala Glu Ala Arg His Arg Ala Gly Met Gln Asn Leu 
545                 550                 555                 560 


Thr Glu Phe Ile Gly Ser Glu Pro Ser Lys Lys Arg Lys Arg Arg Thr 
                565                 570                 575     


Ser Phe Thr Pro Gln Ala Leu Glu Ile Leu Asn Ala His Phe Glu Lys 
            580                 585                 590         


Asn Thr His Pro Ser Gly Gln Glu Met Thr Glu Ile Ala Glu Lys Leu 
        595                 600                 605             


Asn Tyr Asp Arg Glu Val Val Arg Val Trp Phe Cys Asn Lys Arg Gln 
    610                 615                 620                 


Ala Leu Lys Asn Thr Ile Lys Arg Leu Lys Gln His Glu Pro Ala Thr 
625                 630                 635                 640 


Ala Val Pro Leu Glu Pro Leu Thr Asp Ser Leu Glu Glu Asn Ser 
                645                 650                 655 


<210>  2703
<211>  367
<212>  PRT
<213>  homo sapiens

<400>  2703

Met Ala Pro Ser Gly Pro Gly Ser Ser Ala Arg Arg Arg Cys Arg Arg 
1               5                   10                  15      


Val Leu Tyr Trp Ile Pro Val Val Phe Ile Thr Leu Leu Leu Gly Trp 
            20                  25                  30          


Ser Tyr Tyr Ala Tyr Ala Ile Gln Leu Cys Ile Val Ser Met Glu Asn 
        35                  40                  45              


Thr Gly Glu Gln Val Val Cys Leu Met Ala Tyr His Leu Leu Phe Ala 
    50                  55                  60                  


Met Phe Val Trp Ser Tyr Trp Lys Thr Ile Phe Thr Leu Pro Met Asn 
65                  70                  75                  80  


Pro Ser Lys Glu Phe His Leu Ser Tyr Ala Glu Lys Asp Leu Leu Glu 
                85                  90                  95      


Arg Glu Pro Arg Gly Glu Ala His Gln Glu Val Leu Arg Arg Ala Ala 
            100                 105                 110         


Lys Asp Leu Pro Ile Tyr Thr Arg Thr Met Ser Gly Ala Ile Arg Tyr 
        115                 120                 125             


Cys Asp Arg Cys Gln Leu Ile Lys Pro Asp Arg Cys His His Cys Ser 
    130                 135                 140                 


Val Cys Asp Lys Cys Ile Leu Lys Met Asp His His Cys Pro Trp Val 
145                 150                 155                 160 


Asn Asn Cys Val Gly Phe Ser Asn Tyr Lys Phe Phe Leu Leu Phe Leu 
                165                 170                 175     


Ala Tyr Ser Leu Leu Tyr Cys Leu Phe Ile Ala Ala Thr Asp Leu Gln 
            180                 185                 190         


Tyr Phe Ile Lys Phe Trp Thr Asn Gly Leu Pro Asp Thr Gln Ala Lys 
        195                 200                 205             


Phe His Ile Met Phe Leu Phe Phe Ala Ala Ala Met Phe Ser Val Ser 
    210                 215                 220                 


Leu Ser Ser Leu Phe Gly Tyr His Cys Trp Leu Val Ser Lys Asn Lys 
225                 230                 235                 240 


Ser Thr Leu Glu Ala Phe Arg Ser Pro Val Phe Arg His Gly Thr Asp 
                245                 250                 255     


Lys Asn Gly Phe Ser Leu Gly Phe Ser Lys Asn Met Arg Gln Val Phe 
            260                 265                 270         


Gly Asp Glu Lys Lys Tyr Trp Leu Leu Pro Ile Phe Ser Ser Leu Gly 
        275                 280                 285             


Asp Gly Cys Ser Phe Pro Thr Cys Leu Val Asn Gln Asp Pro Glu Gln 
    290                 295                 300                 


Ala Ser Thr Pro Ala Gly Leu Asn Ser Thr Ala Lys Asn Leu Glu Asn 
305                 310                 315                 320 


His Gln Phe Pro Ala Lys Pro Leu Arg Glu Ser Gln Ser His Leu Leu 
                325                 330                 335     


Thr Asp Ser Gln Ser Trp Thr Glu Ser Ser Ile Asn Pro Gly Lys Cys 
            340                 345                 350         


Lys Ala Gly Met Ser Asn Pro Ala Leu Thr Met Glu Asn Glu Thr 
        355                 360                 365         


<210>  2704
<211>  672
<212>  PRT
<213>  homo sapiens

<400>  2704

Met Thr Ala Thr Thr Glu Val Ala Asp Asp Glu Val Thr Glu Gly Thr 
1               5                   10                  15      


Val Thr Gln Ile Gln Ile Leu Gln Asn Glu Gln Leu Asp Glu Ile Ser 
            20                  25                  30          


Pro Leu Gly Asn Glu Glu Val Ser Ala Val Ser Gln Ala Trp Phe Thr 
        35                  40                  45              


Thr Lys Glu Asp Lys Asp Ser Leu Thr Asn Lys Gly His Lys Trp Lys 
    50                  55                  60                  


Gln Gly Met Trp Ser Lys Glu Glu Ile Asp Ile Leu Met Asn Asn Ile 
65                  70                  75                  80  


Glu Arg Tyr Leu Lys Ala Arg Gly Ile Lys Asp Ala Thr Glu Ile Ile 
                85                  90                  95      


Phe Glu Met Ser Lys Asp Glu Arg Lys Asp Phe Tyr Arg Thr Ile Ala 
            100                 105                 110         


Trp Gly Leu Asn Arg Pro Leu Phe Ala Val Tyr Arg Arg Val Leu Arg 
        115                 120                 125             


Met Tyr Asp Asp Arg Asn His Val Gly Lys Tyr Thr Pro Glu Glu Ile 
    130                 135                 140                 


Glu Lys Leu Lys Glu Leu Arg Ile Lys His Gly Asn Asp Trp Ala Thr 
145                 150                 155                 160 


Ile Gly Ala Ala Leu Gly Arg Ser Ala Ser Ser Val Lys Asp Arg Cys 
                165                 170                 175     


Arg Leu Met Lys Asp Thr Cys Asn Thr Gly Lys Trp Thr Glu Glu Glu 
            180                 185                 190         


Glu Lys Arg Leu Ala Glu Val Val His Glu Leu Thr Ser Thr Glu Pro 
        195                 200                 205             


Gly Asp Ile Val Thr Gln Gly Val Ser Trp Ala Ala Val Ala Glu Arg 
    210                 215                 220                 


Val Gly Thr Arg Ser Glu Lys Gln Cys Arg Ser Lys Trp Leu Asn Tyr 
225                 230                 235                 240 


Leu Asn Trp Lys Gln Ser Gly Gly Thr Glu Trp Thr Lys Glu Asp Glu 
                245                 250                 255     


Ile Asn Leu Ile Leu Arg Ile Ala Glu Leu Asp Val Ala Asp Glu Asn 
            260                 265                 270         


Asp Ile Asn Trp Asp Leu Leu Ala Glu Gly Trp Ser Ser Val Arg Ser 
        275                 280                 285             


Pro Gln Trp Leu Arg Ser Lys Trp Trp Thr Ile Lys Arg Gln Ile Ala 
    290                 295                 300                 


Asn His Lys Asp Val Ser Phe Pro Val Leu Ile Lys Gly Leu Lys Gln 
305                 310                 315                 320 


Leu His Glu Asn Gln Lys Asn Asn Pro Thr Leu Leu Glu Asn Lys Ser 
                325                 330                 335     


Gly Ser Gly Val Pro Asn Ser Asn Thr Asn Ser Ser Val Gln His Val 
            340                 345                 350         


Gln Ile Arg Val Ala Arg Leu Glu Asp Asn Thr Ala Ile Ser Ser Ser 
        355                 360                 365             


Pro Met Ala Ala Leu Gln Ile Pro Val Gln Ile Thr His Val Ser Ser 
    370                 375                 380                 


Ala Asp Ser Pro Ala Thr Val Asp Ser Glu Thr Ile Thr Leu Asn Ser 
385                 390                 395                 400 


Gly Thr Leu Gln Thr Phe Glu Ile Leu Pro Ser Phe His Leu Gln Pro 
                405                 410                 415     


Thr Gly Thr Pro Gly Thr Tyr Leu Leu Gln Thr Ser Ser Ser Gln Gly 
            420                 425                 430         


Leu Pro Leu Thr Leu Thr Ala Ser Pro Thr Val Thr Leu Thr Ala Ala 
        435                 440                 445             


Ala Pro Ala Ser Pro Glu Gln Ile Ile Val His Ala Leu Ser Pro Glu 
    450                 455                 460                 


His Leu Leu Asn Thr Ser Asp Asn Val Thr Val Gln Cys His Thr Pro 
465                 470                 475                 480 


Arg Val Ile Ile Gln Thr Val Ala Thr Glu Asp Ile Thr Ser Ser Ile 
                485                 490                 495     


Ser Gln Ala Glu Leu Thr Val Asp Ser Asp Ile Gln Ser Ser Asp Phe 
            500                 505                 510         


Pro Glu Pro Pro Asp Ala Leu Glu Ala Asp Thr Phe Pro Asp Glu Ile 
        515                 520                 525             


His His Pro Lys Met Thr Val Glu Pro Ser Phe Asn Asp Ala His Val 
    530                 535                 540                 


Ser Lys Phe Ser Asp Gln Asn Ser Thr Glu Leu Met Asn Ser Val Met 
545                 550                 555                 560 


Val Arg Thr Glu Glu Glu Ile Ser Asp Thr Asp Leu Lys Gln Glu Glu 
                565                 570                 575     


Ser Pro Ser Asp Leu Ala Ser Ala Tyr Val Thr Glu Gly Leu Glu Ser 
            580                 585                 590         


Pro Thr Ile Glu Glu Gln Val Asp Gln Thr Ile Asp Asp Glu Thr Ile 
        595                 600                 605             


Leu Ile Val Pro Ser Pro His Gly Phe Ile Gln Ala Ser Asp Val Ile 
    610                 615                 620                 


Asp Thr Glu Ser Val Leu Pro Leu Thr Thr Leu Thr Asp Pro Ile Leu 
625                 630                 635                 640 


Gln His His Gln Glu Glu Ser Asn Ile Ile Gly Ser Ser Leu Gly Ser 
                645                 650                 655     


Pro Val Ser Glu Asp Ser Lys Asp Val Glu Asp Leu Val Asn Cys His 
            660                 665                 670         


<210>  2705
<211>  755
<212>  PRT
<213>  homo sapiens

<400>  2705

Met Glu Ala Val Ile Glu Lys Glu Cys Ser Ala Leu Gly Gly Leu Phe 
1               5                   10                  15      


Gln Thr Ile Ile Ser Asp Met Lys Gly Ser Tyr Pro Val Trp Glu Asp 
            20                  25                  30          


Phe Ile Asn Lys Ala Gly Lys Leu Gln Ser Gln Leu Arg Thr Thr Val 
        35                  40                  45              


Val Ala Ala Ala Ala Phe Leu Asp Ala Phe Gln Lys Val Ala Asp Met 
    50                  55                  60                  


Ala Thr Asn Thr Arg Gly Gly Thr Arg Glu Ile Gly Ser Ala Leu Thr 
65                  70                  75                  80  


Arg Met Cys Met Arg His Arg Ser Ile Glu Ala Lys Leu Arg Gln Phe 
                85                  90                  95      


Ser Ser Ala Leu Ile Asp Cys Leu Ile Asn Pro Leu Gln Glu Gln Met 
            100                 105                 110         


Glu Glu Trp Lys Lys Val Ala Asn Gln Leu Asp Lys Asp His Ala Lys 
        115                 120                 125             


Glu Tyr Lys Lys Ala Arg Gln Glu Ile Lys Lys Lys Ser Ser Asp Thr 
    130                 135                 140                 


Leu Lys Leu Gln Lys Lys Ala Lys Lys Gly Arg Gly Asp Ile Gln Pro 
145                 150                 155                 160 


Gln Leu Asp Ser Ala Leu Gln Asp Val Asn Asp Lys Tyr Leu Leu Leu 
                165                 170                 175     


Glu Glu Thr Glu Lys Gln Ala Val Arg Lys Ala Leu Ile Glu Glu Arg 
            180                 185                 190         


Gly Arg Phe Cys Thr Phe Ile Ser Met Leu Arg Pro Val Ile Glu Glu 
        195                 200                 205             


Glu Ile Ser Met Leu Gly Glu Ile Thr His Leu Gln Thr Ile Ser Glu 
    210                 215                 220                 


Asp Leu Lys Ser Leu Thr Met Asp Pro His Lys Leu Pro Ser Ser Ser 
225                 230                 235                 240 


Glu Gln Val Ile Leu Asp Leu Lys Gly Ser Asp Tyr Ser Trp Ser Tyr 
                245                 250                 255     


Gln Thr Pro Pro Ser Ser Pro Ser Thr Thr Met Ser Arg Lys Ser Ser 
            260                 265                 270         


Val Cys Ser Ser Leu Asn Ser Val Asn Ser Ser Asp Ser Arg Ser Ser 
        275                 280                 285             


Gly Ser His Ser His Ser Pro Ser Ser His Tyr Arg Tyr Arg Ser Ser 
    290                 295                 300                 


Asn Leu Ala Gln Gln Ala Pro Val Arg Leu Ser Ser Val Ser Ser His 
305                 310                 315                 320 


Asp Ser Gly Phe Ile Ser Gln Asp Ala Phe Gln Ser Lys Ser Pro Ser 
                325                 330                 335     


Pro Met Pro Pro Glu Ala Pro Asn Gln Leu Ser Asn Gly Phe Ser His 
            340                 345                 350         


Tyr Ser Leu Ser Ser Glu Ser His Val Gly Pro Thr Gly Ala Gly Leu 
        355                 360                 365             


Phe Pro His Cys Leu Pro Ala Ser Arg Leu Leu Pro Arg Val Thr Ser 
    370                 375                 380                 


Val His Leu Pro Asp Tyr Ala His Tyr Tyr Thr Ile Gly Pro Gly Met 
385                 390                 395                 400 


Phe Pro Ser Ser Gln Ile Pro Ser Trp Lys Asp Trp Ala Lys Pro Gly 
                405                 410                 415     


Pro Tyr Asp Gln Pro Leu Val Asn Thr Leu Gln Arg Arg Lys Glu Lys 
            420                 425                 430         


Arg Glu Pro Asp Pro Asn Gly Gly Gly Pro Thr Thr Ala Ser Gly Pro 
        435                 440                 445             


Pro Ala Ala Ala Glu Glu Ala Gln Arg Pro Arg Ser Met Thr Val Ser 
    450                 455                 460                 


Ala Ala Thr Arg Pro Gly Glu Glu Met Glu Ala Cys Glu Glu Leu Ala 
465                 470                 475                 480 


Leu Ala Leu Ser Arg Gly Leu Gln Leu Asp Thr Gln Arg Ser Ser Arg 
                485                 490                 495     


Asp Ser Leu Gln Cys Ser Ser Gly Tyr Ser Thr Gln Thr Thr Thr Pro 
            500                 505                 510         


Cys Cys Ser Glu Asp Thr Ile Pro Ser Gln Val Ser Asp Tyr Asp Tyr 
        515                 520                 525             


Phe Ser Val Ser Gly Asp Gln Glu Ala Asp Gln Gln Glu Phe Asp Lys 
    530                 535                 540                 


Ser Ser Thr Ile Pro Arg Asn Ser Asp Ile Ser Gln Ser Tyr Arg Arg 
545                 550                 555                 560 


Met Phe Gln Ala Lys Arg Pro Ala Ser Thr Ala Gly Leu Pro Thr Thr 
                565                 570                 575     


Leu Gly Pro Ala Met Val Thr Pro Gly Val Ala Thr Ile Arg Arg Thr 
            580                 585                 590         


Pro Ser Thr Lys Pro Ser Val Arg Arg Gly Thr Ile Gly Ala Gly Pro 
        595                 600                 605             


Ile Pro Ile Lys Thr Pro Val Ile Pro Val Lys Thr Pro Thr Val Pro 
    610                 615                 620                 


Asp Leu Pro Gly Val Leu Pro Ala Pro Pro Asp Gly Pro Glu Glu Arg 
625                 630                 635                 640 


Gly Glu His Ser Pro Glu Ser Pro Ser Val Gly Glu Gly Pro Gln Gly 
                645                 650                 655     


Val Thr Ser Met Pro Ser Ser Met Trp Ser Gly Gln Ala Ser Val Asn 
            660                 665                 670         


Pro Pro Leu Pro Gly Pro Lys Pro Ser Ile Pro Glu Glu His Arg Gln 
        675                 680                 685             


Ala Ile Pro Glu Ser Glu Ala Glu Asp Gln Glu Arg Glu Pro Pro Ser 
    690                 695                 700                 


Ala Thr Val Ser Pro Gly Gln Ile Pro Glu Ser Asp Pro Ala Asp Leu 
705                 710                 715                 720 


Ser Pro Arg Asp Thr Pro Gln Gly Glu Asp Met Leu Asn Ala Ile Arg 
                725                 730                 735     


Arg Gly Val Lys Leu Lys Lys Thr Thr Thr Asn Asp Arg Ser Ala Pro 
            740                 745                 750         


Arg Phe Ser 
        755 


<210>  2706
<211>  322
<212>  PRT
<213>  homo sapiens

<400>  2706

Met Pro Val Thr Val Thr Arg Thr Thr Ile Thr Thr Thr Thr Thr Ser 
1               5                   10                  15      


Ser Ser Gly Leu Gly Ser Pro Met Ile Val Gly Ser Pro Arg Ala Leu 
            20                  25                  30          


Thr Gln Pro Leu Gly Leu Leu Arg Leu Leu Gln Leu Val Ser Thr Cys 
        35                  40                  45              


Val Ala Phe Ser Leu Val Ala Ser Val Gly Ala Trp Thr Gly Ser Met 
    50                  55                  60                  


Gly Asn Trp Ser Met Phe Thr Trp Cys Phe Cys Phe Ser Val Thr Leu 
65                  70                  75                  80  


Ile Ile Leu Ile Val Glu Leu Cys Gly Leu Gln Ala Arg Phe Pro Leu 
                85                  90                  95      


Ser Trp Arg Asn Phe Pro Ile Thr Phe Ala Cys Tyr Ala Ala Leu Phe 
            100                 105                 110         


Cys Leu Ser Ala Ser Ile Ile Tyr Pro Thr Thr Tyr Val Gln Phe Leu 
        115                 120                 125             


Ser His Gly Arg Ser Arg Asp His Ala Ile Ala Ala Thr Phe Phe Ser 
    130                 135                 140                 


Cys Ile Ala Cys Val Ala Tyr Ala Thr Glu Val Ala Trp Thr Arg Ala 
145                 150                 155                 160 


Arg Pro Gly Glu Ile Thr Gly Tyr Met Ala Thr Val Pro Gly Leu Leu 
                165                 170                 175     


Lys Val Leu Glu Thr Phe Val Ala Cys Ile Ile Phe Ala Phe Ile Ser 
            180                 185                 190         


Asp Pro Asn Leu Tyr Gln His Gln Pro Ala Leu Glu Trp Cys Val Ala 
        195                 200                 205             


Val Tyr Ala Ile Cys Phe Ile Leu Ala Ala Ile Ala Ile Leu Leu Asn 
    210                 215                 220                 


Leu Gly Glu Cys Thr Asn Val Leu Pro Ile Pro Phe Pro Ser Phe Leu 
225                 230                 235                 240 


Ser Gly Leu Ala Leu Leu Ser Val Leu Leu Tyr Ala Thr Ala Leu Val 
                245                 250                 255     


Leu Trp Pro Leu Tyr Gln Phe Asp Glu Lys Tyr Gly Gly Gln Pro Arg 
            260                 265                 270         


Arg Ser Arg Asp Val Ser Cys Ser Arg Ser His Ala Tyr Tyr Val Cys 
        275                 280                 285             


Ala Trp Asp Arg Arg Leu Ala Val Ala Ile Leu Thr Ala Ile Asn Leu 
    290                 295                 300                 


Leu Ala Tyr Val Ala Asp Leu Val His Ser Ala His Leu Val Phe Val 
305                 310                 315                 320 


Lys Val 
        


<210>  2707
<211>  845
<212>  PRT
<213>  homo sapiens

<400>  2707

Met Leu Ser Gly Val Trp Phe Leu Ser Val Leu Thr Val Ala Gly Ile 
1               5                   10                  15      


Leu Gln Thr Glu Ser Arg Lys Thr Ala Lys Asp Ile Cys Lys Ile Arg 
            20                  25                  30          


Cys Leu Cys Glu Glu Lys Glu Asn Val Leu Asn Ile Asn Cys Glu Asn 
        35                  40                  45              


Lys Gly Phe Thr Thr Val Ser Leu Leu Gln Pro Pro Gln Tyr Arg Ile 
    50                  55                  60                  


Tyr Gln Leu Phe Leu Asn Gly Asn Leu Leu Thr Arg Leu Tyr Pro Asn 
65                  70                  75                  80  


Glu Phe Val Asn Tyr Ser Asn Ala Val Thr Leu His Leu Gly Asn Asn 
                85                  90                  95      


Gly Leu Gln Glu Ile Arg Thr Gly Ala Phe Ser Gly Leu Lys Thr Leu 
            100                 105                 110         


Lys Arg Leu His Leu Asn Asn Asn Lys Leu Glu Ile Leu Arg Glu Asp 
        115                 120                 125             


Thr Phe Leu Gly Leu Glu Ser Leu Glu Tyr Leu Gln Ala Asp Tyr Asn 
    130                 135                 140                 


Tyr Ile Ser Ala Ile Glu Ala Gly Ala Phe Ser Lys Leu Asn Lys Leu 
145                 150                 155                 160 


Lys Val Leu Ile Leu Asn Asp Asn Leu Leu Leu Ser Leu Pro Ser Asn 
                165                 170                 175     


Val Phe Arg Phe Val Leu Leu Thr His Leu Asp Leu Arg Gly Asn Arg 
            180                 185                 190         


Leu Lys Val Met Pro Phe Ala Gly Val Leu Glu His Ile Gly Gly Ile 
        195                 200                 205             


Met Glu Ile Gln Leu Glu Glu Asn Pro Trp Asn Cys Thr Cys Asp Leu 
    210                 215                 220                 


Leu Pro Leu Lys Ala Trp Leu Asp Thr Ile Thr Val Phe Val Gly Glu 
225                 230                 235                 240 


Ile Val Cys Glu Thr Pro Phe Arg Leu His Gly Lys Asp Val Thr Gln 
                245                 250                 255     


Leu Thr Arg Gln Asp Leu Cys Pro Arg Lys Ser Ala Ser Asp Ser Ser 
            260                 265                 270         


Gln Arg Gly Ser His Ala Asp Thr His Val Gln Arg Leu Ser Pro Thr 
        275                 280                 285             


Met Asn Pro Ala Leu Asn Pro Thr Arg Ala Pro Lys Ala Ser Arg Pro 
    290                 295                 300                 


Pro Lys Met Arg Asn Arg Pro Thr Pro Arg Val Thr Val Ser Lys Asp 
305                 310                 315                 320 


Arg Gln Ser Phe Gly Pro Ile Met Val Tyr Gln Thr Lys Ser Pro Val 
                325                 330                 335     


Pro Leu Thr Cys Pro Ser Ser Cys Val Cys Thr Ser Gln Ser Ser Asp 
            340                 345                 350         


Asn Gly Leu Asn Val Asn Cys Gln Glu Arg Lys Phe Thr Asn Ile Ser 
        355                 360                 365             


Asp Leu Gln Pro Lys Pro Thr Ser Pro Lys Lys Leu Tyr Leu Thr Gly 
    370                 375                 380                 


Asn Tyr Leu Gln Thr Val Tyr Lys Asn Asp Leu Leu Glu Tyr Ser Ser 
385                 390                 395                 400 


Leu Asp Leu Leu His Leu Gly Asn Asn Arg Ile Ala Val Ile Gln Glu 
                405                 410                 415     


Gly Ala Phe Thr Asn Leu Thr Ser Leu Arg Arg Leu Tyr Leu Asn Gly 
            420                 425                 430         


Asn Tyr Leu Glu Val Leu Tyr Pro Ser Met Phe Asp Gly Leu Gln Ser 
        435                 440                 445             


Leu Gln Tyr Leu Tyr Leu Glu Tyr Asn Val Ile Lys Glu Ile Lys Pro 
    450                 455                 460                 


Leu Thr Phe Asp Ala Leu Ile Asn Leu Gln Leu Leu Phe Leu Asn Asn 
465                 470                 475                 480 


Asn Leu Leu Arg Ser Leu Pro Asp Asn Ile Phe Gly Gly Thr Ala Leu 
                485                 490                 495     


Thr Arg Leu Asn Leu Arg Asn Asn His Phe Ser His Leu Pro Val Lys 
            500                 505                 510         


Gly Val Leu Asp Gln Leu Pro Ala Phe Ile Gln Ile Asp Leu Gln Glu 
        515                 520                 525             


Asn Pro Trp Asp Cys Thr Cys Asp Ile Met Gly Leu Lys Asp Trp Thr 
    530                 535                 540                 


Glu His Ala Asn Ser Pro Val Ile Ile Asn Glu Val Thr Cys Glu Ser 
545                 550                 555                 560 


Pro Ala Lys His Ala Gly Glu Ile Leu Lys Phe Leu Gly Arg Glu Ala 
                565                 570                 575     


Ile Cys Pro Asp Ser Pro Asn Leu Ser Asp Gly Thr Val Leu Ser Met 
            580                 585                 590         


Asn His Asn Thr Asp Thr Pro Arg Ser Leu Ser Val Ser Pro Ser Ser 
        595                 600                 605             


Tyr Pro Glu Leu His Thr Glu Val Pro Leu Ser Val Leu Ile Leu Gly 
    610                 615                 620                 


Leu Leu Val Val Phe Ile Leu Ser Val Cys Phe Gly Ala Gly Leu Phe 
625                 630                 635                 640 


Val Phe Val Leu Lys Arg Arg Lys Gly Val Pro Ser Val Pro Arg Asn 
                645                 650                 655     


Thr Asn Asn Leu Asp Val Ser Ser Phe Gln Leu Gln Tyr Gly Ser Tyr 
            660                 665                 670         


Asn Thr Glu Thr His Asp Lys Thr Asp Gly His Val Tyr Asn Tyr Ile 
        675                 680                 685             


Pro Pro Pro Val Gly Gln Met Cys Gln Asn Pro Ile Tyr Met Gln Lys 
    690                 695                 700                 


Glu Gly Asp Pro Val Ala Tyr Tyr Arg Asn Leu Gln Glu Phe Ser Tyr 
705                 710                 715                 720 


Ser Asn Leu Glu Glu Lys Lys Glu Glu Pro Ala Thr Pro Ala Tyr Thr 
                725                 730                 735     


Ile Ser Ala Thr Glu Leu Leu Glu Lys Gln Ala Thr Pro Arg Glu Pro 
            740                 745                 750         


Glu Leu Leu Tyr Gln Asn Ile Ala Glu Arg Val Lys Glu Leu Pro Ser 
        755                 760                 765             


Ala Gly Leu Val His Tyr Asn Phe Cys Thr Leu Pro Lys Arg Gln Phe 
    770                 775                 780                 


Ala Pro Ser Tyr Glu Ser Arg Arg Gln Asn Gln Asp Arg Ile Asn Lys 
785                 790                 795                 800 


Thr Val Leu Tyr Gly Thr Pro Arg Lys Cys Phe Val Gly Gln Ser Lys 
                805                 810                 815     


Pro Asn His Pro Leu Leu Gln Ala Lys Pro Gln Ser Glu Pro Asp Tyr 
            820                 825                 830         


Leu Glu Val Leu Glu Lys Gln Thr Ala Ile Ser Gln Leu 
        835                 840                 845 


<210>  2708
<211>  427
<212>  PRT
<213>  homo sapiens

<400>  2708

Met Gly Thr Pro Lys Pro Arg Ile Leu Pro Trp Leu Val Ser Gln Leu 
1               5                   10                  15      


Asp Leu Gly Gln Leu Glu Gly Val Ala Trp Val Asn Lys Ser Arg Thr 
            20                  25                  30          


Arg Phe Arg Ile Pro Trp Lys His Gly Leu Arg Gln Asp Ala Gln Gln 
        35                  40                  45              


Glu Asp Phe Gly Ile Phe Gln Ala Trp Ala Glu Ala Thr Gly Ala Tyr 
    50                  55                  60                  


Val Pro Gly Arg Asp Lys Pro Asp Leu Pro Thr Trp Lys Arg Asn Phe 
65                  70                  75                  80  


Arg Ser Ala Leu Asn Arg Lys Glu Gly Leu Arg Leu Ala Glu Asp Arg 
                85                  90                  95      


Ser Lys Asp Pro His Asp Pro His Lys Ile Tyr Glu Phe Val Asn Ser 
            100                 105                 110         


Gly Val Gly Asp Phe Ser Gln Pro Asp Thr Ser Pro Asp Thr Asn Gly 
        115                 120                 125             


Gly Gly Ser Thr Ser Asp Thr Gln Glu Asp Ile Leu Asp Glu Leu Leu 
    130                 135                 140                 


Gly Asn Met Val Leu Ala Pro Leu Pro Asp Pro Gly Pro Pro Ser Leu 
145                 150                 155                 160 


Ala Val Ala Pro Glu Pro Cys Pro Gln Pro Leu Arg Ser Pro Ser Leu 
                165                 170                 175     


Asp Asn Pro Thr Pro Phe Pro Asn Leu Gly Pro Ser Glu Asn Pro Leu 
            180                 185                 190         


Lys Arg Leu Leu Val Pro Gly Glu Glu Trp Glu Phe Glu Val Thr Ala 
        195                 200                 205             


Phe Tyr Arg Gly Arg Gln Val Phe Gln Gln Thr Ile Ser Cys Pro Glu 
    210                 215                 220                 


Gly Leu Arg Leu Val Gly Ser Glu Val Gly Asp Arg Thr Leu Pro Gly 
225                 230                 235                 240 


Trp Pro Val Thr Leu Pro Asp Pro Gly Met Ser Leu Thr Asp Arg Gly 
                245                 250                 255     


Val Met Ser Tyr Val Arg His Val Leu Ser Cys Leu Gly Gly Gly Leu 
            260                 265                 270         


Ala Leu Trp Arg Ala Gly Gln Trp Leu Trp Ala Gln Arg Leu Gly His 
        275                 280                 285             


Cys His Thr Tyr Trp Ala Val Ser Glu Glu Leu Leu Pro Asn Ser Gly 
    290                 295                 300                 


His Gly Pro Asp Gly Glu Val Pro Lys Asp Lys Glu Gly Gly Val Phe 
305                 310                 315                 320 


Asp Leu Gly Pro Phe Ile Val Asp Leu Ile Thr Phe Thr Glu Gly Ser 
                325                 330                 335     


Gly Arg Ser Pro Arg Tyr Ala Leu Trp Phe Cys Val Gly Glu Ser Trp 
            340                 345                 350         


Pro Gln Asp Gln Pro Trp Thr Lys Arg Leu Val Met Val Lys Val Val 
        355                 360                 365             


Pro Thr Cys Leu Arg Ala Leu Val Glu Met Ala Arg Val Gly Gly Ala 
    370                 375                 380                 


Ser Ser Leu Glu Asn Thr Val Asp Leu His Ile Ser Asn Ser His Pro 
385                 390                 395                 400 


Leu Ser Leu Thr Ser Asp Gln Tyr Lys Ala Tyr Leu Gln Asp Leu Val 
                405                 410                 415     


Glu Gly Met Asp Phe Gln Gly Pro Gly Glu Ser 
            420                 425         


<210>  2709
<211>  503
<212>  PRT
<213>  homo sapiens

<400>  2709

Met Ala Leu Ala Pro Glu Arg Ala Ala Pro Arg Val Leu Phe Gly Glu 
1               5                   10                  15      


Trp Leu Leu Gly Glu Ile Ser Ser Gly Cys Tyr Glu Gly Leu Gln Trp 
            20                  25                  30          


Leu Asp Glu Ala Arg Thr Cys Phe Arg Val Pro Trp Lys His Phe Ala 
        35                  40                  45              


Arg Lys Asp Leu Ser Glu Ala Asp Ala Arg Ile Phe Lys Ala Trp Ala 
    50                  55                  60                  


Val Ala Arg Gly Arg Trp Pro Pro Ser Ser Arg Gly Gly Gly Pro Pro 
65                  70                  75                  80  


Pro Glu Ala Glu Thr Ala Glu Arg Ala Gly Trp Lys Thr Asn Phe Arg 
                85                  90                  95      


Cys Ala Leu Arg Ser Thr Arg Arg Phe Val Met Leu Arg Asp Asn Ser 
            100                 105                 110         


Gly Asp Pro Ala Asp Pro His Lys Val Tyr Ala Leu Ser Arg Glu Leu 
        115                 120                 125             


Cys Trp Arg Glu Gly Pro Gly Thr Asp Gln Thr Glu Ala Glu Ala Pro 
    130                 135                 140                 


Ala Ala Val Pro Pro Pro Gln Gly Gly Pro Pro Gly Pro Phe Leu Ala 
145                 150                 155                 160 


His Thr His Ala Gly Leu Gln Ala Pro Gly Pro Leu Pro Ala Pro Ala 
                165                 170                 175     


Gly Asp Lys Gly Asp Leu Leu Leu Gln Ala Val Gln Gln Ser Cys Leu 
            180                 185                 190         


Ala Asp His Leu Leu Thr Ala Ser Trp Gly Ala Asp Pro Val Pro Thr 
        195                 200                 205             


Lys Ala Pro Gly Glu Gly Gln Glu Gly Leu Pro Leu Thr Gly Ala Cys 
    210                 215                 220                 


Ala Gly Gly Pro Gly Leu Pro Ala Gly Glu Leu Tyr Gly Trp Ala Val 
225                 230                 235                 240 


Glu Thr Thr Pro Ser Pro Gly Pro Gln Pro Ala Ala Leu Thr Thr Gly 
                245                 250                 255     


Glu Ala Ala Ala Pro Glu Ser Pro His Gln Ala Glu Pro Tyr Leu Ser 
            260                 265                 270         


Pro Ser Pro Ser Ala Cys Thr Ala Val Gln Glu Pro Ser Pro Gly Ala 
        275                 280                 285             


Leu Asp Val Thr Ile Met Tyr Lys Gly Arg Thr Val Leu Gln Lys Val 
    290                 295                 300                 


Val Gly His Pro Ser Cys Thr Phe Leu Tyr Gly Pro Pro Asp Pro Ala 
305                 310                 315                 320 


Val Arg Ala Thr Asp Pro Gln Gln Val Ala Phe Pro Ser Pro Ala Glu 
                325                 330                 335     


Leu Pro Asp Gln Lys Gln Leu Arg Tyr Thr Glu Glu Leu Leu Arg His 
            340                 345                 350         


Val Ala Pro Gly Leu His Leu Glu Leu Arg Gly Pro Gln Leu Trp Ala 
        355                 360                 365             


Arg Arg Met Gly Lys Cys Lys Val Tyr Trp Glu Val Gly Gly Pro Pro 
    370                 375                 380                 


Gly Ser Ala Ser Pro Ser Thr Pro Ala Cys Leu Leu Pro Arg Asn Cys 
385                 390                 395                 400 


Asp Thr Pro Ile Phe Asp Phe Arg Val Phe Phe Gln Glu Leu Val Glu 
                405                 410                 415     


Phe Arg Ala Arg Gln Arg Arg Gly Ser Pro Arg Tyr Thr Ile Tyr Leu 
            420                 425                 430         


Gly Phe Gly Gln Asp Leu Ser Ala Gly Arg Pro Lys Glu Lys Ser Leu 
        435                 440                 445             


Val Leu Val Lys Leu Glu Pro Trp Leu Cys Arg Val His Leu Glu Gly 
    450                 455                 460                 


Thr Gln Arg Glu Gly Val Ser Ser Leu Asp Ser Ser Ser Leu Ser Leu 
465                 470                 475                 480 


Cys Leu Ser Ser Ala Asn Ser Leu Tyr Asp Asp Ile Glu Cys Phe Leu 
                485                 490                 495     


Met Glu Leu Glu Gln Pro Ala 
            500             


<210>  2710
<211>  649
<212>  PRT
<213>  homo sapiens

<400>  2710

Met Ala Ser Val Ser Ala Leu Thr Glu Glu Leu Asp Ser Ile Thr Ser 
1               5                   10                  15      


Glu Leu His Ala Val Glu Ile Gln Ile Gln Glu Leu Thr Glu Arg Gln 
            20                  25                  30          


Gln Glu Leu Ile Gln Lys Lys Lys Val Leu Thr Lys Lys Ile Lys Gln 
        35                  40                  45              


Cys Leu Glu Asp Ser Asp Ala Gly Ala Ser Asn Glu Tyr Asp Ser Ser 
    50                  55                  60                  


Pro Ala Ala Trp Asn Lys Glu Asp Phe Pro Trp Ser Gly Lys Val Lys 
65                  70                  75                  80  


Asp Ile Leu Gln Asn Val Phe Lys Leu Glu Lys Phe Arg Pro Leu Gln 
                85                  90                  95      


Leu Glu Thr Ile Asn Val Thr Met Ala Gly Lys Glu Val Phe Leu Val 
            100                 105                 110         


Met Pro Thr Gly Gly Gly Lys Ser Leu Cys Tyr Gln Leu Pro Ala Leu 
        115                 120                 125             


Cys Ser Asp Gly Phe Thr Leu Val Ile Cys Pro Leu Ile Ser Leu Met 
    130                 135                 140                 


Glu Asp Gln Leu Met Val Leu Lys Gln Leu Gly Ile Ser Ala Thr Met 
145                 150                 155                 160 


Leu Asn Ala Ser Ser Ser Lys Glu His Val Lys Trp Val His Ala Glu 
                165                 170                 175     


Met Val Asn Lys Asn Ser Glu Leu Lys Leu Ile Tyr Val Thr Pro Glu 
            180                 185                 190         


Lys Ile Ala Lys Ser Lys Met Phe Met Ser Arg Leu Glu Lys Ala Tyr 
        195                 200                 205             


Glu Ala Arg Arg Phe Thr Arg Ile Ala Val Asp Glu Val His Cys Cys 
    210                 215                 220                 


Ser Gln Trp Gly His Asp Phe Arg Pro Asp Tyr Lys Ala Leu Gly Ile 
225                 230                 235                 240 


Leu Lys Arg Gln Phe Pro Asn Ala Ser Leu Ile Gly Leu Thr Ala Thr 
                245                 250                 255     


Ala Thr Asn His Val Leu Thr Asp Ala Gln Lys Ile Leu Cys Ile Glu 
            260                 265                 270         


Lys Cys Phe Thr Phe Thr Ala Ser Phe Asn Arg Pro Asn Leu Tyr Tyr 
        275                 280                 285             


Glu Val Arg Gln Lys Pro Ser Asn Thr Glu Asp Phe Ile Glu Asp Ile 
    290                 295                 300                 


Val Lys Leu Ile Asn Gly Arg Tyr Lys Gly Gln Ser Gly Ile Ile Tyr 
305                 310                 315                 320 


Cys Phe Ser Gln Lys Asp Ser Glu Gln Val Thr Val Ser Leu Gln Asn 
                325                 330                 335     


Leu Gly Ile His Ala Gly Ala Tyr His Ala Asn Leu Glu Pro Glu Asp 
            340                 345                 350         


Lys Thr Thr Val His Arg Lys Trp Ser Ala Asn Glu Ile Gln Val Val 
        355                 360                 365             


Val Ala Thr Val Ala Phe Gly Met Gly Ile Asp Lys Pro Asp Val Arg 
    370                 375                 380                 


Phe Val Ile His His Ser Met Ser Lys Ser Met Glu Asn Tyr Tyr Gln 
385                 390                 395                 400 


Glu Ser Gly Arg Ala Gly Arg Asp Asp Met Lys Ala Asp Cys Ile Leu 
                405                 410                 415     


Tyr Tyr Gly Phe Gly Asp Ile Phe Arg Ile Ser Ser Met Val Val Met 
            420                 425                 430         


Glu Asn Val Gly Gln Gln Lys Leu Tyr Glu Met Val Ser Tyr Cys Gln 
        435                 440                 445             


Asn Ile Ser Lys Cys Arg Arg Val Leu Met Ala Gln His Phe Asp Glu 
    450                 455                 460                 


Val Trp Asn Ser Glu Ala Cys Asn Lys Met Cys Asp Asn Cys Cys Lys 
465                 470                 475                 480 


Asp Ser Ala Phe Glu Arg Lys Asn Ile Thr Glu Tyr Cys Arg Asp Leu 
                485                 490                 495     


Ile Lys Ile Leu Lys Gln Ala Glu Glu Leu Asn Glu Lys Leu Thr Pro 
            500                 505                 510         


Leu Lys Leu Ile Asp Ser Trp Met Gly Lys Gly Ala Ala Lys Leu Arg 
        515                 520                 525             


Val Ala Gly Val Val Ala Pro Thr Leu Pro Arg Glu Asp Leu Glu Lys 
    530                 535                 540                 


Ile Ile Ala His Phe Leu Ile Gln Gln Tyr Leu Lys Glu Asp Tyr Ser 
545                 550                 555                 560 


Phe Thr Ala Tyr Ala Thr Ile Ser Tyr Leu Lys Ile Gly Pro Lys Ala 
                565                 570                 575     


Asn Leu Leu Asn Asn Glu Ala His Ala Ile Thr Met Gln Val Thr Lys 
            580                 585                 590         


Ser Thr Gln Asn Ser Phe Arg Ala Glu Ser Ser Gln Thr Cys His Ser 
        595                 600                 605             


Glu Gln Gly Asp Lys Lys Met Glu Glu Lys Asn Ser Gly Asn Phe Gln 
    610                 615                 620                 


Lys Lys Ala Ala Asn Met Leu Gln Gln Ser Gly Ser Lys Asn Thr Gly 
625                 630                 635                 640 


Ala Lys Lys Arg Lys Ile Asp Asp Ala 
                645                 


<210>  2711
<211>  406
<212>  PRT
<213>  homo sapiens

<400>  2711

Met Gln Arg Met Ile Gln Gln Phe Ala Ala Glu Tyr Thr Ser Lys Asn 
1               5                   10                  15      


Ser Ser Thr Gln Asp Pro Ser Gln Pro Asn Ser Thr Lys Asn Gln Ser 
            20                  25                  30          


Leu Pro Lys Ala Ser Pro Val Thr Thr Ser Pro Thr Ala Ala Thr Thr 
        35                  40                  45              


Gln Asn Pro Val Leu Ser Lys Leu Leu Met Ala Asp Gln Asp Ser Pro 
    50                  55                  60                  


Leu Asp Leu Thr Val Arg Lys Ser Gln Ser Glu Pro Ser Glu Gln Asp 
65                  70                  75                  80  


Gly Val Leu Asp Leu Ser Thr Lys Lys Ser Pro Cys Ala Gly Ser Thr 
                85                  90                  95      


Ser Leu Ser His Ser Pro Gly Cys Ser Ser Thr Gln Gly Asn Gly Arg 
            100                 105                 110         


Pro Gly Arg Pro Ser Gln Tyr Arg Pro Asp Gly Leu Arg Ser Gly Asp 
        115                 120                 125             


Gly Val Pro Pro Arg Ser Leu Gln Asp Gly Thr Arg Glu Gly Phe Gly 
    130                 135                 140                 


His Ser Thr Ser Leu Lys Val Pro Leu Ala Arg Ser Leu Gln Ile Ser 
145                 150                 155                 160 


Glu Glu Leu Leu Ser Arg Asn Gln Leu Ser Thr Ala Ala Ser Leu Gly 
                165                 170                 175     


Pro Ser Gly Leu Gln Asn His Gly Gln His Leu Ile Leu Ser Arg Glu 
            180                 185                 190         


Ala Ser Trp Ala Lys Pro His Tyr Glu Phe Asn Leu Ser Arg Met Lys 
        195                 200                 205             


Phe Arg Gly Asn Gly Ala Leu Ser Asn Ile Ser Asp Leu Pro Phe Leu 
    210                 215                 220                 


Ala Glu Asn Ser Ala Phe Pro Lys Met Ala Leu Gln Ala Lys Gln Asp 
225                 230                 235                 240 


Gly Lys Lys Asp Val Ser His Ser Ser Pro Val Asp Leu Lys Ile Pro 
                245                 250                 255     


Gln Val Arg Gly Met Asp Leu Ser Trp Glu Ser Arg Thr Gly Asp Gln 
            260                 265                 270         


Tyr Ser Tyr Ser Ser Leu Val Met Gly Ser Gln Thr Glu Ser Ala Leu 
        275                 280                 285             


Ser Lys Lys Leu Arg Ala Ile Leu Pro Lys Gln Ser Arg Lys Ser Met 
    290                 295                 300                 


Leu Asp Ala Gly Pro Asp Ser Trp Gly Ser Asp Ala Glu Gln Ser Thr 
305                 310                 315                 320 


Ser Gly Gln Pro Tyr Pro Thr Ser Asp Gln Glu Gly Asp Pro Gly Ser 
                325                 330                 335     


Lys Gln Pro Arg Lys Lys Arg Gly Arg Tyr Arg Gln Tyr Asn Ser Glu 
            340                 345                 350         


Ile Leu Glu Glu Ala Ile Ser Val Val Met Ser Gly Lys Met Ser Val 
        355                 360                 365             


Ser Lys Ala Gln Ser Ile Tyr Gly Ile Pro His Ser Thr Leu Glu Tyr 
    370                 375                 380                 


Lys Val Lys Glu Arg Leu Gly Thr Leu Lys Asn Pro Pro Lys Lys Lys 
385                 390                 395                 400 


Met Lys Leu Met Ser Gly 
                405     


<210>  2712
<211>  353
<212>  PRT
<213>  homo sapiens

<400>  2712

Met Leu Gln Leu Phe Ile Gly Thr Ala Asp Asp Arg Leu Leu Arg Pro 
1               5                   10                  15      


His Ala Phe Tyr Gln Val His Arg Ile Thr Gly Lys Thr Val Ser Thr 
            20                  25                  30          


Thr Ser His Glu Ala Ile Leu Ser Asn Thr Lys Val Leu Glu Ile Pro 
        35                  40                  45              


Leu Leu Pro Glu Asn Ser Met Arg Ala Val Ile Asp Cys Ala Gly Ile 
    50                  55                  60                  


Leu Lys Leu Arg Asn Ser Asp Ile Glu Leu Arg Lys Gly Glu Thr Asp 
65                  70                  75                  80  


Ile Gly Arg Lys Asn Thr Arg Val Arg Leu Val Phe Arg Val His Val 
                85                  90                  95      


Pro Gln Pro Ser Gly Arg Thr Leu Ser Leu Gln Val Ala Ser Asn Pro 
            100                 105                 110         


Ile Glu Cys Ser Gln Arg Ser Ala Gln Glu Leu Pro Leu Val Glu Lys 
        115                 120                 125             


Gln Ser Thr Asp Ser Tyr Pro Val Val Gly Gly Lys Lys Met Val Leu 
    130                 135                 140                 


Ser Gly His Asn Phe Leu Gln Asp Ser Lys Val Ile Phe Val Glu Lys 
145                 150                 155                 160 


Ala Pro Asp Gly His His Val Trp Glu Met Glu Ala Lys Thr Asp Arg 
                165                 170                 175     


Asp Leu Cys Lys Pro Asn Ser Leu Val Val Glu Ile Pro Pro Phe Arg 
            180                 185                 190         


Asn Gln Arg Ile Thr Ser Pro Val His Val Ser Phe Tyr Val Cys Asn 
        195                 200                 205             


Gly Lys Arg Lys Arg Ser Gln Tyr Gln Arg Phe Thr Tyr Leu Pro Ala 
    210                 215                 220                 


Asn Val Pro Ile Ile Lys Thr Glu Pro Thr Asp Asp Tyr Glu Pro Ala 
225                 230                 235                 240 


Pro Thr Cys Gly Pro Val Ser Gln Gly Leu Ser Pro Leu Pro Arg Pro 
                245                 250                 255     


Tyr Tyr Ser Gln Gln Leu Ala Met Pro Pro Asp Pro Ser Ser Cys Leu 
            260                 265                 270         


Val Ala Gly Phe Pro Pro Cys Pro Gln Arg Ser Thr Leu Met Pro Ala 
        275                 280                 285             


Ala Pro Gly Val Ser Pro Lys Leu His Asp Leu Ser Pro Ala Ala Tyr 
    290                 295                 300                 


Thr Lys Gly Val Ala Ser Pro Gly His Cys His Leu Gly Leu Pro Gln 
305                 310                 315                 320 


Pro Ala Gly Glu Ala Pro Ala Val Gln Asp Val Pro Arg Pro Val Ala 
                325                 330                 335     


Thr His Pro Gly Ser Pro Gly Gln Pro Pro Pro Ala Leu Leu Pro Gln 
            340                 345                 350         


Gln 
    


<210>  2713
<211>  104
<212>  PRT
<213>  homo sapiens

<400>  2713

Met Lys Ser Cys Gln Lys Met Glu Gly Lys Pro Glu Asn Glu Ser Glu 
1               5                   10                  15      


Pro Lys His Glu Glu Glu Pro Lys Pro Glu Glu Lys Pro Glu Glu Glu 
            20                  25                  30          


Glu Lys Leu Glu Glu Glu Ala Lys Ala Lys Gly Thr Phe Arg Glu Arg 
        35                  40                  45              


Leu Ile Gln Ser Leu Gln Glu Phe Lys Glu Asp Ile His Asn Arg His 
    50                  55                  60                  


Leu Ser Asn Glu Asp Met Phe Arg Glu Val Asp Glu Ile Asp Glu Ile 
65                  70                  75                  80  


Arg Arg Val Arg Asn Lys Leu Ile Val Met Arg Trp Lys Val Asn Arg 
                85                  90                  95      


Asn His Pro Tyr Pro Tyr Leu Met 
            100                 


<210>  2714
<211>  199
<212>  PRT
<213>  homo sapiens

<400>  2714

Met Ala Asn Arg Gly Pro Ser Tyr Gly Leu Ser Arg Glu Val Gln Glu 
1               5                   10                  15      


Lys Ile Glu Gln Lys Tyr Asp Ala Asp Leu Glu Asn Lys Leu Val Asp 
            20                  25                  30          


Trp Ile Ile Leu Gln Cys Ala Glu Asp Ile Glu His Pro Pro Pro Gly 
        35                  40                  45              


Arg Ala His Phe Gln Lys Trp Leu Met Asp Gly Thr Val Leu Cys Lys 
    50                  55                  60                  


Leu Ile Asn Ser Leu Tyr Pro Pro Gly Gln Glu Pro Ile Pro Lys Ile 
65                  70                  75                  80  


Ser Glu Ser Lys Met Ala Phe Lys Gln Met Glu Gln Ile Ser Gln Phe 
                85                  90                  95      


Leu Lys Ala Ala Glu Thr Tyr Gly Val Arg Thr Thr Asp Ile Phe Gln 
            100                 105                 110         


Thr Val Asp Leu Trp Glu Gly Lys Asp Met Ala Ala Val Gln Arg Thr 
        115                 120                 125             


Leu Met Ala Leu Gly Ser Val Ala Val Thr Lys Asp Asp Gly Cys Tyr 
    130                 135                 140                 


Arg Gly Glu Pro Ser Trp Phe His Arg Lys Ala Gln Gln Asn Arg Arg 
145                 150                 155                 160 


Gly Phe Ser Glu Glu Gln Leu Arg Gln Gly Gln Asn Val Ile Gly Leu 
                165                 170                 175     


Gln Met Gly Ser Asn Lys Gly Ala Ser Gln Ala Gly Met Thr Gly Tyr 
            180                 185                 190         


Gly Met Pro Arg Gln Ile Met 
        195                 


<210>  2715
<211>  199
<212>  PRT
<213>  homo sapiens

<400>  2715

Met Ala Asn Arg Gly Pro Ser Tyr Gly Leu Ser Arg Glu Val Gln Glu 
1               5                   10                  15      


Lys Ile Glu Gln Lys Tyr Asp Ala Asp Leu Glu Asn Lys Leu Val Asp 
            20                  25                  30          


Trp Ile Ile Leu Gln Cys Ala Glu Asp Ile Glu His Pro Pro Pro Gly 
        35                  40                  45              


Arg Ala His Phe Gln Lys Trp Leu Met Asp Gly Thr Val Leu Cys Lys 
    50                  55                  60                  


Leu Ile Asn Ser Leu Tyr Pro Pro Gly Gln Glu Pro Ile Pro Lys Ile 
65                  70                  75                  80  


Ser Glu Ser Lys Met Ala Phe Lys Gln Met Glu Gln Ile Ser Gln Phe 
                85                  90                  95      


Leu Lys Ala Ala Glu Thr Tyr Gly Val Arg Thr Thr Asp Ile Phe Gln 
            100                 105                 110         


Thr Val Asp Leu Trp Glu Gly Lys Asp Met Ala Ala Val Gln Arg Thr 
        115                 120                 125             


Leu Met Ala Leu Gly Ser Val Ala Val Thr Lys Asp Asp Gly Cys Tyr 
    130                 135                 140                 


Arg Gly Glu Pro Ser Trp Phe His Arg Lys Ala Gln Gln Asn Arg Arg 
145                 150                 155                 160 


Gly Phe Ser Glu Glu Gln Leu Arg Gln Gly Gln Asn Val Ile Gly Leu 
                165                 170                 175     


Gln Met Gly Ser Asn Lys Gly Ala Ser Gln Ala Gly Met Thr Gly Tyr 
            180                 185                 190         


Gly Met Pro Arg Gln Ile Met 
        195                 


<210>  2716
<211>  1266
<212>  PRT
<213>  homo sapiens

<400>  2716

Met Trp Val Asn Pro Glu Glu Val Leu Leu Ala Asn Ala Leu Trp Ile 
1               5                   10                  15      


Thr Glu Arg Ala Asn Pro Tyr Phe Ile Leu Gln Arg Arg Lys Gly His 
            20                  25                  30          


Ala Gly Asp Gly Gly Gly Gly Gly Gly Leu Ala Gly Leu Leu Val Gly 
        35                  40                  45              


Thr Leu Asp Val Val Leu Asp Ser Ser Ala Arg Val Ala Pro Tyr Arg 
    50                  55                  60                  


Ile Leu Tyr Gln Thr Pro Asp Ser Leu Val Tyr Trp Thr Ile Ala Cys 
65                  70                  75                  80  


Gly Gly Ser Arg Lys Glu Ile Thr Glu His Trp Glu Trp Leu Glu Gln 
                85                  90                  95      


Asn Leu Leu Gln Thr Leu Ser Ile Phe Glu Asn Glu Asn Asp Ile Thr 
            100                 105                 110         


Thr Phe Val Arg Gly Lys Ile Gln Gly Ile Ile Ala Glu Tyr Asn Lys 
        115                 120                 125             


Ile Asn Asp Val Lys Glu Asp Asp Asp Thr Glu Lys Phe Lys Glu Ala 
    130                 135                 140                 


Ile Val Lys Phe His Arg Leu Phe Gly Met Pro Glu Glu Glu Lys Leu 
145                 150                 155                 160 


Val Asn Tyr Tyr Ser Cys Ser Tyr Trp Lys Gly Lys Val Pro Arg Gln 
                165                 170                 175     


Gly Trp Met Tyr Leu Ser Ile Asn His Leu Cys Phe Tyr Ser Phe Leu 
            180                 185                 190         


Met Gly Arg Glu Ala Lys Leu Val Ile Arg Trp Val Asp Ile Thr Gln 
        195                 200                 205             


Leu Glu Lys Asn Ala Thr Leu Leu Leu Pro Asp Val Ile Lys Val Ser 
    210                 215                 220                 


Thr Arg Ser Ser Glu His Phe Phe Ser Val Phe Leu Asn Ile Asn Glu 
225                 230                 235                 240 


Thr Phe Lys Leu Met Glu Gln Leu Ala Asn Ile Ala Met Arg Gln Leu 
                245                 250                 255     


Leu Asp Asn Glu Gly Phe Glu Gln Asp Arg Ser Leu Pro Lys Leu Lys 
            260                 265                 270         


Arg Lys Ser Pro Lys Lys Val Ser Ala Leu Lys Arg Asp Leu Asp Ala 
        275                 280                 285             


Arg Ala Lys Ser Glu Arg Tyr Arg Ala Leu Phe Arg Leu Pro Lys Asp 
    290                 295                 300                 


Glu Lys Leu Asp Gly His Thr Asp Cys Thr Leu Trp Thr Pro Phe Asn 
305                 310                 315                 320 


Lys Met His Ile Leu Gly Gln Met Phe Val Ser Thr Asn Tyr Ile Cys 
                325                 330                 335     


Phe Thr Ser Lys Glu Glu Asn Leu Cys Ser Leu Ile Ile Pro Leu Arg 
            340                 345                 350         


Glu Val Thr Ile Val Glu Lys Ala Asp Ser Ser Ser Val Leu Pro Ser 
        355                 360                 365             


Pro Leu Ser Ile Ser Thr Arg Asn Arg Met Thr Phe Leu Phe Ala Asn 
    370                 375                 380                 


Leu Lys Asp Arg Asp Phe Leu Val Gln Arg Ile Ser Asp Phe Leu Gln 
385                 390                 395                 400 


Gln Thr Thr Ser Lys Ile Tyr Ser Asp Lys Glu Phe Ala Gly Ser Tyr 
                405                 410                 415     


Asn Ser Ser Asp Asp Glu Val Tyr Ser Arg Pro Ser Ser Leu Val Ser 
            420                 425                 430         


Ser Ser Pro Gln Arg Ser Thr Ser Ser Asp Ala Asp Gly Glu Arg Gln 
        435                 440                 445             


Phe Asn Leu Asn Gly Asn Ser Val Pro Thr Ala Thr Gln Thr Leu Met 
    450                 455                 460                 


Thr Met Tyr Arg Arg Arg Ser Pro Glu Glu Phe Asn Pro Lys Leu Ala 
465                 470                 475                 480 


Lys Glu Phe Leu Lys Glu Gln Ala Trp Lys Ile His Phe Ala Glu Tyr 
                485                 490                 495     


Gly Gln Gly Ile Cys Met Tyr Arg Thr Glu Lys Thr Arg Glu Leu Val 
            500                 505                 510         


Leu Lys Gly Ile Pro Glu Ser Met Arg Gly Glu Leu Trp Leu Leu Leu 
        515                 520                 525             


Ser Gly Ala Ile Asn Glu Lys Ala Thr His Pro Gly Tyr Tyr Glu Asp 
    530                 535                 540                 


Leu Val Glu Lys Ser Met Gly Lys Tyr Asn Leu Ala Thr Glu Glu Ile 
545                 550                 555                 560 


Glu Arg Asp Leu His Arg Ser Leu Pro Glu His Pro Ala Phe Gln Asn 
                565                 570                 575     


Glu Met Gly Ile Ala Ala Leu Arg Arg Val Leu Thr Ala Tyr Ala Phe 
            580                 585                 590         


Arg Asn Pro Asn Ile Gly Tyr Cys Gln Ala Met Asn Ile Val Thr Ser 
        595                 600                 605             


Val Leu Leu Leu Tyr Ala Lys Glu Glu Glu Ala Phe Trp Leu Leu Val 
    610                 615                 620                 


Ala Leu Cys Glu Arg Met Leu Pro Asp Tyr Tyr Asn Thr Arg Val Val 
625                 630                 635                 640 


Gly Ala Leu Val Asp Gln Gly Val Phe Glu Glu Leu Ala Arg Asp Tyr 
                645                 650                 655     


Val Pro Gln Leu Tyr Asp Cys Met Gln Asp Leu Gly Val Ile Ser Thr 
            660                 665                 670         


Ile Ser Leu Ser Trp Phe Leu Thr Leu Phe Leu Ser Val Met Pro Phe 
        675                 680                 685             


Glu Ser Ala Val Val Val Val Asp Cys Phe Phe Tyr Glu Gly Ile Lys 
    690                 695                 700                 


Val Ile Phe Gln Leu Ala Leu Ala Val Leu Asp Ala Asn Val Asp Lys 
705                 710                 715                 720 


Leu Leu Asn Cys Lys Asp Asp Gly Glu Ala Met Thr Val Leu Gly Arg 
                725                 730                 735     


Tyr Leu Asp Ser Val Thr Asn Lys Asp Ser Thr Leu Pro Pro Ile Pro 
            740                 745                 750         


His Leu His Ser Leu Leu Ser Asp Asp Val Glu Pro Tyr Pro Glu Val 
        755                 760                 765             


Asp Ile Phe Arg Leu Ile Arg Thr Ser Tyr Glu Lys Phe Gly Thr Ile 
    770                 775                 780                 


Arg Ala Asp Leu Ile Glu Gln Met Arg Phe Lys Gln Arg Leu Lys Val 
785                 790                 795                 800 


Ile Gln Thr Leu Glu Asp Thr Thr Lys Arg Asn Val Val Arg Thr Ile 
                805                 810                 815     


Val Thr Glu Thr Ser Phe Thr Ile Asp Glu Leu Glu Glu Leu Tyr Ala 
            820                 825                 830         


Leu Phe Lys Ala Glu His Leu Thr Ser Cys Tyr Trp Gly Gly Ser Ser 
        835                 840                 845             


Asn Ala Leu Asp Arg His Asp Pro Ser Leu Pro Tyr Leu Glu Gln Tyr 
    850                 855                 860                 


Arg Ile Asp Phe Glu Gln Phe Lys Gly Met Phe Ala Leu Leu Phe Pro 
865                 870                 875                 880 


Trp Ala Cys Gly Thr His Ser Asp Val Leu Ala Ser Arg Leu Phe Gln 
                885                 890                 895     


Leu Leu Asp Glu Asn Gly Asp Ser Leu Ile Asn Phe Arg Glu Phe Val 
            900                 905                 910         


Ser Gly Leu Ser Ala Ala Cys His Gly Asp Leu Thr Glu Lys Leu Lys 
        915                 920                 925             


Leu Leu Tyr Lys Met His Val Leu Pro Glu Pro Ser Ser Asp Gln Asp 
    930                 935                 940                 


Glu Pro Asp Ser Ala Phe Glu Ala Thr Gln Tyr Phe Phe Glu Asp Ile 
945                 950                 955                 960 


Thr Pro Glu Cys Thr His Val Val Gly Leu Asp Ser Arg Ser Lys Gln 
                965                 970                 975     


Gly Ala Asp Asp Gly Phe Val Thr Val Ser Leu Lys Pro Asp Lys Gly 
            980                 985                 990         


Lys Arg Ala Asn Ser Gln Glu Asn  Arg Asn Tyr Leu Arg  Leu Trp Thr 
        995                 1000                 1005             


Pro Glu  Asn Lys Ser Lys Ser  Lys Asn Ala Lys Asp  Leu Pro Lys 
    1010                 1015                 1020             


Leu Asn  Gln Gly Gln Phe Ile  Glu Leu Cys Lys Thr  Met Tyr Asn 
    1025                 1030                 1035             


Met Phe  Ser Glu Asp Pro Asn  Glu Gln Glu Leu Tyr  His Ala Thr 
    1040                 1045                 1050             


Ala Ala  Val Thr Ser Leu Leu  Leu Glu Ile Gly Glu  Val Gly Lys 
    1055                 1060                 1065             


Leu Phe  Val Ala Gln Pro Ala  Lys Glu Gly Gly Ser  Gly Gly Ser 
    1070                 1075                 1080             


Gly Pro  Ser Cys His Gln Gly  Ile Pro Gly Val Leu  Phe Pro Lys 
    1085                 1090                 1095             


Lys Gly  Pro Gly Gln Pro Tyr  Val Val Glu Ser Val  Glu Pro Leu 
    1100                 1105                 1110             


Pro Ala  Ser Leu Ala Pro Asp  Ser Glu Glu His Ser  Leu Gly Gly 
    1115                 1120                 1125             


Gln Met  Glu Asp Ile Lys Leu  Glu Asp Ser Ser Pro  Arg Asp Asn 
    1130                 1135                 1140             


Gly Ala  Cys Ser Ser Met Leu  Ile Ser Asp Asp Asp  Thr Lys Asp 
    1145                 1150                 1155             


Asp Ser  Ser Met Ser Ser Tyr  Ser Val Leu Ser Ala  Gly Ser His 
    1160                 1165                 1170             


Glu Glu  Asp Lys Leu His Cys  Glu Asp Ile Gly Glu  Asp Thr Val 
    1175                 1180                 1185             


Leu Val  Arg Ser Gly Gln Gly  Thr Ala Ala Leu Pro  Arg Ser Thr 
    1190                 1195                 1200             


Ser Leu  Asp Arg Asp Trp Ala  Ile Thr Phe Glu Gln  Phe Leu Ala 
    1205                 1210                 1215             


Ser Leu  Leu Thr Glu Pro Ala  Leu Val Lys Tyr Phe  Asp Lys Pro 
    1220                 1225                 1230             


Val Cys  Met Met Ala Arg Ile  Thr Ser Ala Lys Asn  Ile Arg Met 
    1235                 1240                 1245             


Met Gly  Lys Pro Leu Thr Ser  Ala Ser Asp Tyr Glu  Ile Ser Ala 
    1250                 1255                 1260             


Met Ser  Gly 
    1265     


<210>  2717
<211>  926
<212>  PRT
<213>  homo sapiens

<400>  2717

Met Leu Gln Val His Arg Thr Gly Leu Gly Arg Leu Gly Val Ser Leu 
1               5                   10                  15      


Ser Lys Gly Leu His His Lys Ala Val Leu Ala Val Arg Arg Glu Asp 
            20                  25                  30          


Val Asn Ala Trp Glu Arg Arg Ala Pro Leu Ala Pro Lys His Ile Lys 
        35                  40                  45              


Gly Ile Thr Asn Leu Gly Tyr Lys Val Leu Ile Gln Pro Ser Asn Arg 
    50                  55                  60                  


Arg Ala Ile His Asp Lys Asp Tyr Val Lys Ala Gly Gly Ile Leu Gln 
65                  70                  75                  80  


Glu Asp Ile Ser Glu Ala Cys Leu Ile Leu Gly Val Lys Arg Pro Pro 
                85                  90                  95      


Glu Glu Lys Leu Met Ser Arg Lys Thr Tyr Ala Phe Phe Ser His Thr 
            100                 105                 110         


Ile Lys Ala Gln Glu Ala Asn Met Gly Leu Leu Asp Glu Ile Leu Lys 
        115                 120                 125             


Gln Glu Ile Arg Leu Ile Asp Tyr Glu Lys Met Val Asp His Arg Gly 
    130                 135                 140                 


Val Arg Val Val Ala Phe Gly Gln Trp Ala Gly Val Ala Gly Met Ile 
145                 150                 155                 160 


Asn Ile Leu His Gly Met Gly Leu Arg Leu Leu Ala Leu Gly His His 
                165                 170                 175     


Thr Pro Phe Met His Ile Gly Met Ala His Asn Tyr Arg Asn Ser Ser 
            180                 185                 190         


Gln Ala Val Gln Ala Val Arg Asp Ala Gly Tyr Glu Ile Ser Leu Gly 
        195                 200                 205             


Leu Met Pro Lys Ser Ile Gly Pro Leu Thr Phe Val Phe Thr Gly Thr 
    210                 215                 220                 


Gly Asn Val Ser Lys Gly Ala Gln Ala Ile Phe Asn Glu Leu Pro Cys 
225                 230                 235                 240 


Glu Tyr Val Glu Pro His Glu Leu Lys Glu Val Ser Gln Thr Gly Asp 
                245                 250                 255     


Leu Arg Lys Val Tyr Gly Thr Val Leu Ser Arg His His His Leu Val 
            260                 265                 270         


Arg Lys Thr Asp Ala Val Tyr Asp Pro Ala Glu Tyr Asp Lys His Pro 
        275                 280                 285             


Glu Arg Tyr Ile Ser Arg Phe Asn Thr Asp Ile Ala Pro Tyr Thr Thr 
    290                 295                 300                 


Cys Leu Ile Asn Gly Ile Tyr Trp Glu Gln Asn Thr Pro Arg Leu Leu 
305                 310                 315                 320 


Thr Arg Gln Asp Ala Gln Ser Leu Leu Ala Pro Gly Lys Phe Ser Pro 
                325                 330                 335     


Ala Gly Val Glu Gly Cys Pro Ala Leu Pro His Lys Leu Val Ala Ile 
            340                 345                 350         


Cys Asp Ile Ser Ala Asp Thr Gly Gly Ser Ile Glu Phe Met Thr Glu 
        355                 360                 365             


Cys Thr Thr Ile Glu His Pro Phe Cys Met Tyr Asp Ala Asp Gln His 
    370                 375                 380                 


Ile Ile His Asp Ser Val Glu Gly Ser Gly Ile Leu Met Cys Ser Ile 
385                 390                 395                 400 


Asp Asn Leu Pro Ala Gln Leu Pro Ile Glu Ala Thr Glu Cys Phe Gly 
                405                 410                 415     


Asp Met Leu Tyr Pro Tyr Val Glu Glu Met Ile Leu Ser Asp Ala Thr 
            420                 425                 430         


Gln Pro Leu Glu Ser Gln Asn Phe Ser Pro Val Val Arg Asp Ala Val 
        435                 440                 445             


Ile Thr Ser Asn Gly Thr Leu Pro Asp Lys Tyr Lys Tyr Ile Gln Thr 
    450                 455                 460                 


Leu Arg Glu Ser Arg Glu Arg Ala Gln Ser Leu Ser Met Gly Thr Arg 
465                 470                 475                 480 


Arg Lys Val Leu Val Leu Gly Ser Gly Tyr Ile Ser Glu Pro Val Leu 
                485                 490                 495     


Glu Tyr Leu Ser Arg Asp Gly Asn Ile Glu Ile Thr Val Gly Ser Asp 
            500                 505                 510         


Met Lys Asn Gln Ile Glu Gln Leu Gly Lys Lys Tyr Asn Ile Asn Pro 
        515                 520                 525             


Val Ser Met Asp Ile Cys Lys Gln Glu Glu Lys Leu Gly Phe Leu Val 
    530                 535                 540                 


Ala Lys Gln Asp Leu Val Ile Ser Leu Leu Pro Tyr Val Leu His Pro 
545                 550                 555                 560 


Leu Val Ala Lys Ala Cys Ile Thr Asn Lys Val Asn Met Val Thr Ala 
                565                 570                 575     


Ser Tyr Ile Thr Pro Ala Leu Lys Glu Leu Glu Lys Ser Val Glu Asp 
            580                 585                 590         


Ala Gly Ile Thr Ile Ile Gly Glu Leu Gly Leu Asp Pro Gly Leu Asp 
        595                 600                 605             


His Met Leu Ala Met Glu Thr Ile Asp Lys Ala Lys Glu Val Gly Ala 
    610                 615                 620                 


Thr Ile Glu Ser Tyr Ile Ser Tyr Cys Gly Gly Leu Pro Ala Pro Glu 
625                 630                 635                 640 


His Ser Asn Asn Pro Leu Arg Tyr Lys Phe Ser Trp Ser Pro Val Gly 
                645                 650                 655     


Val Leu Met Asn Val Met Gln Ser Ala Thr Tyr Leu Leu Asp Gly Lys 
            660                 665                 670         


Val Val Asn Val Ala Gly Gly Ile Ser Phe Leu Asp Ala Val Thr Ser 
        675                 680                 685             


Met Asp Phe Phe Pro Gly Leu Asn Leu Glu Gly Tyr Pro Asn Arg Asp 
    690                 695                 700                 


Ser Thr Lys Tyr Ala Glu Ile Tyr Gly Ile Ser Ser Ala His Thr Leu 
705                 710                 715                 720 


Leu Arg Gly Thr Leu Arg Tyr Lys Gly Tyr Met Lys Ala Leu Asn Gly 
                725                 730                 735     


Phe Val Lys Leu Gly Leu Ile Asn Arg Glu Ala Leu Pro Ala Phe Arg 
            740                 745                 750         


Pro Glu Ala Asn Pro Leu Thr Trp Lys Gln Leu Leu Cys Asp Leu Val 
        755                 760                 765             


Gly Ile Ser Pro Ser Ser Glu His Asp Val Leu Lys Glu Ala Val Leu 
    770                 775                 780                 


Lys Lys Leu Gly Gly Asp Asn Thr Gln Leu Glu Ala Ala Glu Trp Leu 
785                 790                 795                 800 


Gly Leu Leu Gly Asp Glu Gln Val Pro Gln Ala Glu Ser Ile Leu Asp 
                805                 810                 815     


Ala Leu Ser Lys His Leu Val Met Lys Leu Ser Tyr Gly Pro Glu Glu 
            820                 825                 830         


Lys Asp Met Ile Val Met Arg Asp Ser Phe Gly Ile Arg His Pro Ser 
        835                 840                 845             


Gly His Leu Glu His Lys Thr Ile Asp Leu Val Ala Tyr Gly Asp Ile 
    850                 855                 860                 


Asn Gly Phe Ser Ala Met Ala Lys Thr Val Gly Leu Pro Thr Ala Met 
865                 870                 875                 880 


Ala Ala Lys Met Leu Leu Asp Gly Glu Ile Gly Ala Lys Gly Leu Met 
                885                 890                 895     


Gly Pro Phe Ser Lys Glu Ile Tyr Gly Pro Ile Leu Glu Arg Ile Lys 
            900                 905                 910         


Ala Glu Gly Ile Ile Tyr Thr Thr Gln Ser Thr Ile Lys Pro 
        915                 920                 925     


<210>  2718
<211>  835
<212>  PRT
<213>  homo sapiens

<400>  2718

Met Ser Arg Arg Lys Gln Gly Lys Pro Gln His Leu Ser Lys Arg Glu 
1               5                   10                  15      


Phe Ser Pro Glu Pro Leu Glu Ala Ile Leu Thr Asp Asp Glu Pro Asp 
            20                  25                  30          


His Gly Pro Leu Gly Ala Pro Glu Gly Asp His Asp Leu Leu Thr Cys 
        35                  40                  45              


Gly Gln Cys Gln Met Asn Phe Pro Leu Gly Asp Ile Leu Ile Phe Ile 
    50                  55                  60                  


Glu His Lys Arg Lys Gln Cys Asn Gly Ser Leu Cys Leu Glu Lys Ala 
65                  70                  75                  80  


Val Asp Lys Pro Pro Ser Pro Ser Pro Ile Glu Met Lys Lys Ala Ser 
                85                  90                  95      


Asn Pro Val Glu Val Gly Ile Gln Val Thr Pro Glu Asp Asp Asp Cys 
            100                 105                 110         


Leu Ser Thr Ser Ser Arg Gly Ile Cys Pro Lys Gln Glu His Ile Ala 
        115                 120                 125             


Asp Lys Leu Leu His Trp Arg Gly Leu Ser Ser Pro Arg Ser Ala His 
    130                 135                 140                 


Gly Ala Leu Ile Pro Thr Pro Gly Met Ser Ala Glu Tyr Ala Pro Gln 
145                 150                 155                 160 


Gly Ile Cys Lys Asp Glu Pro Ser Ser Tyr Thr Cys Thr Thr Cys Lys 
                165                 170                 175     


Gln Pro Phe Thr Ser Ala Trp Phe Leu Leu Gln His Ala Gln Asn Thr 
            180                 185                 190         


His Gly Leu Arg Ile Tyr Leu Glu Ser Glu His Gly Ser Pro Leu Thr 
        195                 200                 205             


Pro Arg Val Gly Ile Pro Ser Gly Leu Gly Ala Glu Cys Pro Ser Gln 
    210                 215                 220                 


Pro Pro Leu His Gly Ile His Ile Ala Asp Asn Asn Pro Phe Asn Leu 
225                 230                 235                 240 


Leu Arg Ile Pro Gly Ser Val Ser Arg Glu Ala Ser Gly Leu Ala Glu 
                245                 250                 255     


Gly Arg Phe Pro Pro Thr Pro Pro Leu Phe Ser Pro Pro Pro Arg His 
            260                 265                 270         


His Leu Asp Pro His Arg Ile Glu Arg Leu Gly Ala Glu Glu Met Ala 
        275                 280                 285             


Leu Ala Thr His His Pro Ser Ala Phe Asp Arg Val Leu Arg Leu Asn 
    290                 295                 300                 


Pro Met Ala Met Glu Pro Pro Ala Met Asp Phe Ser Arg Arg Leu Arg 
305                 310                 315                 320 


Glu Leu Ala Gly Asn Thr Ser Ser Pro Pro Leu Ser Pro Gly Arg Pro 
                325                 330                 335     


Ser Pro Met Gln Arg Leu Leu Gln Pro Phe Gln Pro Gly Ser Lys Pro 
            340                 345                 350         


Pro Phe Leu Ala Thr Pro Pro Leu Pro Pro Leu Gln Ser Ala Pro Pro 
        355                 360                 365             


Pro Ser Gln Pro Pro Val Lys Ser Lys Ser Cys Glu Phe Cys Gly Lys 
    370                 375                 380                 


Thr Phe Lys Phe Gln Ser Asn Leu Val Val His Arg Arg Ser His Thr 
385                 390                 395                 400 


Gly Glu Lys Pro Tyr Lys Cys Asn Leu Cys Asp His Ala Cys Thr Gln 
                405                 410                 415     


Ala Ser Lys Leu Lys Arg His Met Lys Thr His Met His Lys Ser Ser 
            420                 425                 430         


Pro Met Thr Val Lys Ser Asp Asp Gly Leu Ser Thr Ala Ser Ser Pro 
        435                 440                 445             


Glu Pro Gly Thr Ser Asp Leu Val Gly Ser Ala Ser Ser Ala Leu Lys 
    450                 455                 460                 


Ser Val Val Ala Lys Phe Lys Ser Glu Asn Asp Pro Asn Leu Ile Pro 
465                 470                 475                 480 


Glu Asn Gly Asp Glu Glu Glu Glu Glu Asp Asp Glu Glu Glu Glu Glu 
                485                 490                 495     


Glu Glu Glu Glu Glu Glu Glu Glu Leu Thr Glu Ser Glu Arg Val Asp 
            500                 505                 510         


Tyr Gly Phe Gly Leu Ser Leu Glu Ala Ala Arg His His Glu Asn Ser 
        515                 520                 525             


Ser Arg Gly Ala Val Val Gly Val Gly Asp Glu Ser Arg Ala Leu Pro 
    530                 535                 540                 


Asp Val Met Gln Gly Met Val Leu Ser Ser Met Gln His Phe Ser Glu 
545                 550                 555                 560 


Ala Phe His Gln Val Leu Gly Glu Lys His Lys Arg Gly His Leu Ala 
                565                 570                 575     


Glu Ala Glu Gly His Arg Asp Thr Cys Asp Glu Asp Ser Val Ala Gly 
            580                 585                 590         


Glu Ser Asp Arg Ile Asp Asp Gly Thr Val Asn Gly Arg Gly Cys Ser 
        595                 600                 605             


Pro Gly Glu Ser Ala Ser Gly Gly Leu Ser Lys Lys Leu Leu Leu Gly 
    610                 615                 620                 


Ser Pro Ser Ser Leu Ser Pro Phe Ser Lys Arg Ile Lys Leu Glu Lys 
625                 630                 635                 640 


Glu Phe Asp Leu Pro Pro Ala Ala Met Pro Asn Thr Glu Asn Val Tyr 
                645                 650                 655     


Ser Gln Trp Leu Ala Gly Tyr Ala Ala Ser Arg Gln Leu Lys Asp Pro 
            660                 665                 670         


Phe Leu Ser Phe Gly Asp Ser Arg Gln Ser Pro Phe Ala Ser Ser Ser 
        675                 680                 685             


Glu His Ser Ser Glu Asn Gly Ser Leu Arg Phe Ser Thr Pro Pro Gly 
    690                 695                 700                 


Glu Leu Asp Gly Gly Ile Ser Gly Arg Ser Gly Thr Gly Ser Gly Gly 
705                 710                 715                 720 


Ser Thr Pro His Ile Ser Gly Pro Gly Pro Gly Arg Pro Ser Ser Lys 
                725                 730                 735     


Glu Gly Arg Arg Ser Asp Thr Cys Glu Tyr Cys Gly Lys Val Phe Lys 
            740                 745                 750         


Asn Cys Ser Asn Leu Thr Val His Arg Arg Ser His Thr Gly Glu Arg 
        755                 760                 765             


Pro Tyr Lys Cys Glu Leu Cys Asn Tyr Ala Cys Ala Gln Ser Ser Lys 
    770                 775                 780                 


Leu Thr Arg His Met Lys Thr His Gly Gln Val Gly Lys Asp Val Tyr 
785                 790                 795                 800 


Lys Cys Glu Ile Cys Lys Met Pro Phe Ser Val Tyr Ser Thr Leu Glu 
                805                 810                 815     


Lys His Met Lys Lys Trp His Ser Asp Arg Val Leu Asn Asn Asp Ile 
            820                 825                 830         


Lys Thr Glu 
        835 


<210>  2719
<211>  117
<212>  PRT
<213>  homo sapiens

<400>  2719

Met Lys Trp Met Phe Lys Glu Asp His Ser Leu Glu His Arg Cys Val 
1               5                   10                  15      


Glu Ser Ala Lys Ile Arg Ala Lys Tyr Pro Asp Arg Val Pro Val Ile 
            20                  25                  30          


Val Glu Lys Val Ser Gly Ser Gln Ile Val Asp Ile Asp Lys Arg Lys 
        35                  40                  45              


Tyr Leu Val Pro Ser Asp Ile Thr Val Ala Gln Phe Met Trp Ile Ile 
    50                  55                  60                  


Arg Lys Arg Ile Gln Leu Pro Ser Glu Lys Ala Ile Phe Leu Phe Val 
65                  70                  75                  80  


Asp Lys Thr Val Pro Gln Ser Ser Leu Thr Met Gly Gln Leu Tyr Glu 
                85                  90                  95      


Lys Glu Lys Asp Glu Asp Gly Phe Leu Tyr Val Ala Tyr Ser Gly Glu 
            100                 105                 110         


Asn Thr Phe Gly Phe 
        115         


<210>  2720
<211>  941
<212>  PRT
<213>  homo sapiens

<400>  2720

Met Ala Ser Pro Arg Ser Ser Gly Gln Pro Gly Pro Pro Pro Pro Pro 
1               5                   10                  15      


Pro Pro Pro Pro Ala Arg Leu Leu Leu Leu Leu Leu Leu Pro Leu Leu 
            20                  25                  30          


Leu Pro Leu Ala Pro Gly Ala Trp Gly Trp Ala Arg Gly Ala Pro Arg 
        35                  40                  45              


Pro Pro Pro Ser Ser Pro Pro Leu Ser Ile Met Gly Leu Met Pro Leu 
    50                  55                  60                  


Thr Lys Glu Val Ala Lys Gly Ser Ile Gly Arg Gly Val Leu Pro Ala 
65                  70                  75                  80  


Val Glu Leu Ala Ile Glu Gln Ile Arg Asn Glu Ser Leu Leu Arg Pro 
                85                  90                  95      


Tyr Phe Leu Asp Leu Arg Leu Tyr Asp Thr Glu Cys Asp Asn Ala Lys 
            100                 105                 110         


Gly Leu Lys Ala Phe Tyr Asp Ala Ile Lys Tyr Gly Pro Asn His Leu 
        115                 120                 125             


Met Val Phe Gly Gly Val Cys Pro Ser Val Thr Ser Ile Ile Ala Glu 
    130                 135                 140                 


Ser Leu Gln Gly Trp Asn Leu Val Gln Leu Ser Phe Ala Ala Thr Thr 
145                 150                 155                 160 


Pro Val Leu Ala Asp Lys Lys Lys Tyr Pro Tyr Phe Phe Arg Thr Val 
                165                 170                 175     


Pro Ser Asp Asn Ala Val Asn Pro Ala Ile Leu Lys Leu Leu Lys His 
            180                 185                 190         


Tyr Gln Trp Lys Arg Val Gly Thr Leu Thr Gln Asp Val Gln Arg Phe 
        195                 200                 205             


Ser Glu Val Arg Asn Asp Leu Thr Gly Val Leu Tyr Gly Glu Asp Ile 
    210                 215                 220                 


Glu Ile Ser Asp Thr Glu Ser Phe Ser Asn Asp Pro Cys Thr Ser Val 
225                 230                 235                 240 


Lys Lys Leu Lys Gly Asn Asp Val Arg Ile Ile Leu Gly Gln Phe Asp 
                245                 250                 255     


Gln Asn Met Ala Ala Lys Val Phe Cys Cys Ala Tyr Glu Glu Asn Met 
            260                 265                 270         


Tyr Gly Ser Lys Tyr Gln Trp Ile Ile Pro Gly Trp Tyr Glu Pro Ser 
        275                 280                 285             


Trp Trp Glu Gln Val His Thr Glu Ala Asn Ser Ser Arg Cys Leu Arg 
    290                 295                 300                 


Lys Asn Leu Leu Ala Ala Met Glu Gly Tyr Ile Gly Val Asp Phe Glu 
305                 310                 315                 320 


Pro Leu Ser Ser Lys Gln Ile Lys Thr Ile Ser Gly Lys Thr Pro Gln 
                325                 330                 335     


Gln Tyr Glu Arg Glu Tyr Asn Asn Lys Arg Ser Gly Val Gly Pro Ser 
            340                 345                 350         


Lys Phe His Gly Tyr Ala Tyr Asp Gly Ile Trp Val Ile Ala Lys Thr 
        355                 360                 365             


Leu Gln Arg Ala Met Glu Thr Leu His Ala Ser Ser Arg His Gln Arg 
    370                 375                 380                 


Ile Gln Asp Phe Asn Tyr Thr Asp His Thr Leu Gly Arg Ile Ile Leu 
385                 390                 395                 400 


Asn Ala Met Asn Glu Thr Asn Phe Phe Gly Val Thr Gly Gln Val Val 
                405                 410                 415     


Phe Arg Asn Gly Glu Arg Met Gly Thr Ile Lys Phe Thr Gln Phe Gln 
            420                 425                 430         


Asp Ser Arg Glu Val Lys Val Gly Glu Tyr Asn Ala Val Ala Asp Thr 
        435                 440                 445             


Leu Glu Ile Ile Asn Asp Thr Ile Arg Phe Gln Gly Ser Glu Pro Pro 
    450                 455                 460                 


Lys Asp Lys Thr Ile Ile Leu Glu Gln Leu Arg Lys Ile Ser Leu Pro 
465                 470                 475                 480 


Leu Tyr Ser Ile Leu Ser Ala Leu Thr Ile Leu Gly Met Ile Met Ala 
                485                 490                 495     


Ser Ala Phe Leu Phe Phe Asn Ile Lys Asn Arg Asn Gln Lys Leu Ile 
            500                 505                 510         


Lys Met Ser Ser Pro Tyr Met Asn Asn Leu Ile Ile Leu Gly Gly Met 
        515                 520                 525             


Leu Ser Tyr Ala Ser Ile Phe Leu Phe Gly Leu Asp Gly Ser Phe Val 
    530                 535                 540                 


Ser Glu Lys Thr Phe Glu Thr Leu Cys Thr Val Arg Thr Trp Ile Leu 
545                 550                 555                 560 


Thr Val Gly Tyr Thr Thr Ala Phe Gly Ala Met Phe Ala Lys Thr Trp 
                565                 570                 575     


Arg Val His Ala Ile Phe Lys Asn Val Lys Met Lys Lys Lys Ile Ile 
            580                 585                 590         


Lys Asp Gln Lys Leu Leu Val Ile Val Gly Gly Met Leu Leu Ile Asp 
        595                 600                 605             


Leu Cys Ile Leu Ile Cys Trp Gln Ala Val Asp Pro Leu Arg Arg Thr 
    610                 615                 620                 


Val Glu Lys Tyr Ser Met Glu Pro Asp Pro Ala Gly Arg Asp Ile Ser 
625                 630                 635                 640 


Ile Arg Pro Leu Leu Glu His Cys Glu Asn Thr His Met Thr Ile Trp 
                645                 650                 655     


Leu Gly Ile Val Tyr Ala Tyr Lys Gly Leu Leu Met Leu Phe Gly Cys 
            660                 665                 670         


Phe Leu Ala Trp Glu Thr Arg Asn Val Ser Ile Pro Ala Leu Asn Asp 
        675                 680                 685             


Ser Lys Tyr Ile Gly Met Ser Val Tyr Asn Val Gly Ile Met Cys Ile 
    690                 695                 700                 


Ile Gly Ala Ala Val Ser Phe Leu Thr Arg Asp Gln Pro Asn Val Gln 
705                 710                 715                 720 


Phe Cys Ile Val Ala Leu Val Ile Ile Phe Cys Ser Thr Ile Thr Leu 
                725                 730                 735     


Cys Leu Val Phe Val Pro Lys Leu Ile Thr Leu Arg Thr Asn Pro Asp 
            740                 745                 750         


Ala Ala Thr Gln Asn Arg Arg Phe Gln Phe Thr Gln Asn Gln Lys Lys 
        755                 760                 765             


Glu Asp Ser Lys Thr Ser Thr Ser Val Thr Ser Val Asn Gln Ala Ser 
    770                 775                 780                 


Thr Ser Arg Leu Glu Gly Leu Gln Ser Glu Asn His Arg Leu Arg Met 
785                 790                 795                 800 


Lys Ile Thr Glu Leu Asp Lys Asp Leu Glu Glu Val Thr Met Gln Leu 
                805                 810                 815     


Gln Asp Thr Pro Glu Lys Thr Thr Tyr Ile Lys Gln Asn His Tyr Gln 
            820                 825                 830         


Glu Leu Asn Asp Ile Leu Asn Leu Gly Asn Phe Thr Glu Ser Thr Asp 
        835                 840                 845             


Gly Gly Lys Ala Ile Leu Lys Asn His Leu Asp Gln Asn Pro Gln Leu 
    850                 855                 860                 


Gln Trp Asn Thr Thr Glu Pro Ser Arg Thr Cys Lys Asp Pro Ile Glu 
865                 870                 875                 880 


Asp Ile Asn Ser Pro Glu His Ile Gln Arg Arg Leu Ser Leu Gln Leu 
                885                 890                 895     


Pro Ile Leu His His Ala Tyr Leu Pro Ser Ile Gly Gly Val Asp Ala 
            900                 905                 910         


Ser Cys Val Ser Pro Cys Val Ser Pro Thr Ala Ser Pro Arg His Arg 
        915                 920                 925             


His Val Pro Pro Ser Phe Arg Val Met Val Ser Gly Leu 
    930                 935                 940     


<210>  2721
<211>  233
<212>  PRT
<213>  homo sapiens

<400>  2721

Met Trp Ser Gly Leu Leu Pro Pro Gly Leu Asn Glu Ser Asp Ala Glu 
1               5                   10                  15      


Ser Asn Ser Glu Asp Glu Ala Thr Leu Glu Asn Ser Gly Leu Asn Leu 
            20                  25                  30          


Gln Glu Asp Lys Glu Asp Glu Ser Ile Arg Lys Thr Glu Ile Ile Asp 
        35                  40                  45              


Phe Ser Thr Asp Glu Pro Lys Thr Glu Thr Glu Ser Asn Val Asn Ala 
    50                  55                  60                  


Tyr Glu Glu Cys Pro Ser Gly Ile Pro Ile Asp Met Trp Asn Lys Phe 
65                  70                  75                  80  


Gln Glu Leu His Lys Lys His Ser Glu Gln Lys Ser Thr Thr Ser Arg 
                85                  90                  95      


Phe Arg Gly Lys Arg Arg Lys Arg Ser Arg Lys Asp Lys Leu Lys Asn 
            100                 105                 110         


Glu Lys Glu Leu His Ser Glu Pro Ser Ser Asn Glu Thr Gln Trp Lys 
        115                 120                 125             


Glu Leu Thr Gln Tyr Phe Gly Val Asn Asp Arg Phe Asp Pro Pro Val 
    130                 135                 140                 


Lys Arg Lys Lys Val Glu Lys Ser Gly Leu Glu Lys Arg Ile Asp Gln 
145                 150                 155                 160 


Ala Val Glu Glu Trp Asn Ile Glu Lys Ala Glu Glu Leu Ser Asn Gln 
                165                 170                 175     


Leu Ala Thr Arg Glu Leu Gly Val Lys Ile Ala Lys Ala Val Ala Cys 
            180                 185                 190         


His Asn Phe Val Lys Ala Lys Lys Glu Val Glu Asn Ser Gln Ala Ala 
        195                 200                 205             


Arg Lys Lys Lys Lys Leu Ala Trp Gly Phe Glu Ala Lys Lys Arg Trp 
    210                 215                 220                 


Glu Thr Lys Ser Asn Met Gly Tyr Met 
225                 230             


<210>  2722
<211>  3256
<212>  PRT
<213>  homo sapiens

<400>  2722

Met Trp Pro Thr Arg Arg Leu Val Thr Ile Lys Arg Ser Gly Val Asp 
1               5                   10                  15      


Gly Pro His Phe Pro Leu Ser Leu Ser Thr Cys Leu Phe Gly Arg Gly 
            20                  25                  30          


Ile Glu Cys Asp Ile Arg Ile Gln Leu Pro Val Val Ser Lys Gln His 
        35                  40                  45              


Cys Lys Ile Glu Ile His Glu Gln Glu Ala Ile Leu His Asn Phe Ser 
    50                  55                  60                  


Ser Thr Asn Pro Thr Gln Val Asn Gly Ser Val Ile Asp Glu Pro Val 
65                  70                  75                  80  


Arg Leu Lys His Gly Asp Val Ile Thr Ile Ile Asp Arg Ser Phe Arg 
                85                  90                  95      


Tyr Glu Asn Glu Ser Leu Gln Asn Gly Arg Lys Ser Thr Glu Phe Pro 
            100                 105                 110         


Arg Lys Ile Arg Glu Gln Glu Pro Ala Arg Arg Val Ser Arg Ser Ser 
        115                 120                 125             


Phe Ser Ser Asp Pro Asp Glu Lys Ala Gln Asp Ser Lys Ala Tyr Ser 
    130                 135                 140                 


Lys Ile Thr Glu Gly Lys Val Ser Gly Asn Pro Gln Val His Ile Lys 
145                 150                 155                 160 


Asn Val Lys Glu Asp Ser Thr Ala Asp Asp Ser Lys Asp Ser Val Ala 
                165                 170                 175     


Gln Gly Thr Thr Asn Val His Ser Ser Glu His Ala Gly Arg Asn Gly 
            180                 185                 190         


Arg Asn Ala Ala Asp Pro Ile Ser Gly Asp Phe Lys Glu Ile Ser Ser 
        195                 200                 205             


Val Lys Leu Val Ser Arg Tyr Gly Glu Leu Lys Ser Val Pro Thr Thr 
    210                 215                 220                 


Gln Cys Leu Asp Asn Ser Lys Lys Asn Glu Ser Pro Phe Trp Lys Leu 
225                 230                 235                 240 


Tyr Glu Ser Val Lys Lys Glu Leu Asp Val Lys Ser Gln Lys Glu Asn 
                245                 250                 255     


Val Leu Gln Tyr Cys Arg Lys Ser Gly Leu Gln Thr Asp Tyr Ala Thr 
            260                 265                 270         


Glu Lys Glu Ser Ala Asp Gly Leu Gln Gly Glu Thr Gln Leu Leu Val 
        275                 280                 285             


Ser Arg Lys Ser Arg Pro Lys Ser Gly Gly Ser Gly His Ala Val Ala 
    290                 295                 300                 


Glu Pro Ala Ser Pro Glu Gln Glu Leu Asp Gln Asn Lys Gly Lys Gly 
305                 310                 315                 320 


Arg Asp Val Glu Ser Val Gln Thr Pro Ser Lys Ala Val Gly Ala Ser 
                325                 330                 335     


Phe Pro Leu Tyr Glu Pro Ala Lys Met Lys Thr Pro Val Gln Tyr Ser 
            340                 345                 350         


Gln Gln Gln Asn Ser Pro Gln Lys His Lys Asn Lys Asp Leu Tyr Thr 
        355                 360                 365             


Thr Gly Arg Arg Glu Ser Val Asn Leu Gly Lys Ser Glu Gly Phe Lys 
    370                 375                 380                 


Ala Gly Asp Lys Thr Leu Thr Pro Arg Lys Leu Ser Thr Arg Asn Arg 
385                 390                 395                 400 


Thr Pro Ala Lys Val Glu Asp Ala Ala Asp Ser Ala Thr Lys Pro Glu 
                405                 410                 415     


Asn Leu Ser Ser Lys Thr Arg Gly Ser Ile Pro Thr Asp Val Glu Val 
            420                 425                 430         


Leu Pro Thr Glu Thr Glu Ile His Asn Glu Pro Phe Leu Thr Leu Trp 
        435                 440                 445             


Leu Thr Gln Val Glu Arg Lys Ile Gln Lys Asp Ser Leu Ser Lys Pro 
    450                 455                 460                 


Glu Lys Leu Gly Thr Thr Ala Gly Gln Met Cys Ser Gly Leu Pro Gly 
465                 470                 475                 480 


Leu Ser Ser Val Asp Ile Asn Asn Phe Gly Asp Ser Ile Asn Glu Ser 
                485                 490                 495     


Glu Gly Ile Pro Leu Lys Arg Arg Arg Val Ser Phe Gly Gly His Leu 
            500                 505                 510         


Arg Pro Glu Leu Phe Asp Glu Asn Leu Pro Pro Asn Thr Pro Leu Lys 
        515                 520                 525             


Arg Gly Glu Ala Pro Thr Lys Arg Lys Ser Leu Val Met His Thr Pro 
    530                 535                 540                 


Pro Val Leu Lys Lys Ile Ile Lys Glu Gln Pro Gln Pro Ser Gly Lys 
545                 550                 555                 560 


Gln Glu Ser Gly Ser Glu Ile His Val Glu Val Lys Ala Gln Ser Leu 
                565                 570                 575     


Val Ile Ser Pro Pro Ala Pro Ser Pro Arg Lys Thr Pro Val Ala Ser 
            580                 585                 590         


Asp Gln Arg Arg Arg Ser Cys Lys Thr Ala Pro Ala Ser Ser Ser Lys 
        595                 600                 605             


Ser Gln Thr Glu Val Pro Lys Arg Gly Gly Arg Lys Ser Gly Asn Leu 
    610                 615                 620                 


Pro Ser Lys Arg Val Ser Ile Ser Arg Ser Gln His Asp Ile Leu Gln 
625                 630                 635                 640 


Met Ile Cys Ser Lys Arg Arg Ser Gly Ala Ser Glu Ala Asn Leu Ile 
                645                 650                 655     


Val Ala Lys Ser Trp Ala Asp Val Val Lys Leu Gly Ala Lys Gln Thr 
            660                 665                 670         


Gln Thr Lys Val Ile Lys His Gly Pro Gln Arg Ser Met Asn Lys Arg 
        675                 680                 685             


Gln Arg Arg Pro Ala Thr Pro Lys Lys Pro Val Gly Glu Val His Ser 
    690                 695                 700                 


Gln Phe Ser Thr Gly His Ala Asn Ser Pro Cys Thr Ile Ile Ile Gly 
705                 710                 715                 720 


Lys Ala His Thr Glu Lys Val His Val Pro Ala Arg Pro Tyr Arg Val 
                725                 730                 735     


Leu Asn Asn Phe Ile Ser Asn Gln Lys Met Asp Phe Lys Glu Asp Leu 
            740                 745                 750         


Ser Gly Ile Ala Glu Met Phe Lys Thr Pro Val Lys Glu Gln Pro Gln 
        755                 760                 765             


Leu Thr Ser Thr Cys His Ile Ala Ile Ser Asn Ser Glu Asn Leu Leu 
    770                 775                 780                 


Gly Lys Gln Phe Gln Gly Thr Asp Ser Gly Glu Glu Pro Leu Leu Pro 
785                 790                 795                 800 


Thr Ser Glu Ser Phe Gly Gly Asn Val Phe Phe Ser Ala Gln Asn Ala 
                805                 810                 815     


Ala Lys Gln Pro Ser Asp Lys Cys Ser Ala Ser Pro Pro Leu Arg Arg 
            820                 825                 830         


Gln Cys Ile Arg Glu Asn Gly Asn Val Ala Lys Thr Pro Arg Asn Thr 
        835                 840                 845             


Tyr Lys Met Thr Ser Leu Glu Thr Lys Thr Ser Asp Thr Glu Thr Glu 
    850                 855                 860                 


Pro Ser Lys Thr Val Ser Thr Ala Asn Arg Ser Gly Arg Ser Thr Glu 
865                 870                 875                 880 


Phe Arg Asn Ile Gln Lys Leu Pro Val Glu Ser Lys Ser Glu Glu Thr 
                885                 890                 895     


Asn Thr Glu Ile Val Glu Cys Ile Leu Lys Arg Gly Gln Lys Ala Thr 
            900                 905                 910         


Leu Leu Gln Gln Arg Arg Glu Gly Glu Met Lys Glu Ile Glu Arg Pro 
        915                 920                 925             


Phe Glu Thr Tyr Lys Glu Asn Ile Glu Leu Lys Glu Asn Asp Glu Lys 
    930                 935                 940                 


Met Lys Ala Met Lys Arg Ser Arg Thr Trp Gly Gln Lys Cys Ala Pro 
945                 950                 955                 960 


Met Ser Asp Leu Thr Asp Leu Lys Ser Leu Pro Asp Thr Glu Leu Met 
                965                 970                 975     


Lys Asp Thr Ala Arg Gly Gln Asn Leu Leu Gln Thr Gln Asp His Ala 
            980                 985                 990         


Lys Ala Pro Lys Ser Glu Lys Gly  Lys Ile Thr Lys Met  Pro Cys Gln 
        995                 1000                 1005             


Ser Leu  Gln Pro Glu Pro Ile  Asn Thr Pro Thr His  Thr Lys Gln 
    1010                 1015                 1020             


Gln Leu  Lys Ala Ser Leu Gly  Lys Val Gly Val Lys  Glu Glu Leu 
    1025                 1030                 1035             


Leu Ala  Val Gly Lys Phe Thr  Arg Thr Ser Gly Glu  Thr Thr His 
    1040                 1045                 1050             


Thr His  Arg Glu Pro Ala Gly  Asp Gly Lys Ser Ile  Arg Thr Phe 
    1055                 1060                 1065             


Lys Glu  Ser Pro Lys Gln Ile  Leu Asp Pro Ala Ala  Arg Val Thr 
    1070                 1075                 1080             


Gly Met  Lys Lys Trp Pro Arg  Thr Pro Lys Glu Glu  Ala Gln Ser 
    1085                 1090                 1095             


Leu Glu  Asp Leu Ala Gly Phe  Lys Glu Leu Phe Gln  Thr Pro Gly 
    1100                 1105                 1110             


Pro Ser  Glu Glu Ser Met Thr  Asp Glu Lys Thr Thr  Lys Ile Ala 
    1115                 1120                 1125             


Cys Lys  Ser Pro Pro Pro Glu  Ser Val Asp Thr Pro  Thr Ser Thr 
    1130                 1135                 1140             


Lys Gln  Trp Pro Lys Arg Ser  Leu Arg Lys Ala Asp  Val Glu Glu 
    1145                 1150                 1155             


Glu Phe  Leu Ala Leu Arg Lys  Leu Thr Pro Ser Ala  Gly Lys Ala 
    1160                 1165                 1170             


Met Leu  Thr Pro Lys Pro Ala  Gly Gly Asp Glu Lys  Asp Ile Lys 
    1175                 1180                 1185             


Ala Phe  Met Gly Thr Pro Val  Gln Lys Leu Asp Leu  Ala Gly Thr 
    1190                 1195                 1200             


Leu Pro  Gly Ser Lys Arg Gln  Leu Gln Thr Pro Lys  Glu Lys Ala 
    1205                 1210                 1215             


Gln Ala  Leu Glu Asp Leu Ala  Gly Phe Lys Glu Leu  Phe Gln Thr 
    1220                 1225                 1230             


Pro Gly  His Thr Glu Glu Leu  Val Ala Ala Gly Lys  Thr Thr Lys 
    1235                 1240                 1245             


Ile Pro  Cys Asp Ser Pro Gln  Ser Asp Pro Val Asp  Thr Pro Thr 
    1250                 1255                 1260             


Ser Thr  Lys Gln Arg Pro Lys  Arg Ser Ile Arg Lys  Ala Asp Val 
    1265                 1270                 1275             


Glu Gly  Glu Leu Leu Ala Cys  Arg Asn Leu Met Pro  Ser Ala Gly 
    1280                 1285                 1290             


Lys Ala  Met His Thr Pro Lys  Pro Ser Val Gly Glu  Glu Lys Asp 
    1295                 1300                 1305             


Ile Ile  Ile Phe Val Gly Thr  Pro Val Gln Lys Leu  Asp Leu Thr 
    1310                 1315                 1320             


Glu Asn  Leu Thr Gly Ser Lys  Arg Arg Pro Gln Thr  Pro Lys Glu 
    1325                 1330                 1335             


Glu Ala  Gln Ala Leu Glu Asp  Leu Thr Gly Phe Lys  Glu Leu Phe 
    1340                 1345                 1350             


Gln Thr  Pro Gly His Thr Glu  Glu Ala Val Ala Ala  Gly Lys Thr 
    1355                 1360                 1365             


Thr Lys  Met Pro Cys Glu Ser  Ser Pro Pro Glu Ser  Ala Asp Thr 
    1370                 1375                 1380             


Pro Thr  Ser Thr Arg Arg Gln  Pro Lys Thr Pro Leu  Glu Lys Arg 
    1385                 1390                 1395             


Asp Val  Gln Lys Glu Leu Ser  Ala Leu Lys Lys Leu  Thr Gln Thr 
    1400                 1405                 1410             


Ser Gly  Glu Thr Thr His Thr  Asp Lys Val Pro Gly  Gly Glu Asp 
    1415                 1420                 1425             


Lys Ser  Ile Asn Ala Phe Arg  Glu Thr Ala Lys Gln  Lys Leu Asp 
    1430                 1435                 1440             


Pro Ala  Ala Ser Val Thr Gly  Ser Lys Arg His Pro  Lys Thr Lys 
    1445                 1450                 1455             


Glu Lys  Ala Gln Pro Leu Glu  Asp Leu Ala Gly Leu  Lys Glu Leu 
    1460                 1465                 1470             


Phe Gln  Thr Pro Val Cys Thr  Asp Lys Pro Thr Thr  His Glu Lys 
    1475                 1480                 1485             


Thr Thr  Lys Ile Ala Cys Arg  Ser Gln Pro Asp Pro  Val Asp Thr 
    1490                 1495                 1500             


Pro Thr  Ser Ser Lys Pro Gln  Ser Lys Arg Ser Leu  Arg Lys Val 
    1505                 1510                 1515             


Asp Val  Glu Glu Glu Phe Phe  Ala Leu Arg Lys Arg  Thr Pro Ser 
    1520                 1525                 1530             


Ala Gly  Lys Ala Met His Thr  Pro Lys Pro Ala Val  Ser Gly Glu 
    1535                 1540                 1545             


Lys Asn  Ile Tyr Ala Phe Met  Gly Thr Pro Val Gln  Lys Leu Asp 
    1550                 1555                 1560             


Leu Thr  Glu Asn Leu Thr Gly  Ser Lys Arg Arg Leu  Gln Thr Pro 
    1565                 1570                 1575             


Lys Glu  Lys Ala Gln Ala Leu  Glu Asp Leu Ala Gly  Phe Lys Glu 
    1580                 1585                 1590             


Leu Phe  Gln Thr Arg Gly His  Thr Glu Glu Ser Met  Thr Asn Asp 
    1595                 1600                 1605             


Lys Thr  Ala Lys Val Ala Cys  Lys Ser Ser Gln Pro  Asp Pro Asp 
    1610                 1615                 1620             


Lys Asn  Pro Ala Ser Ser Lys  Arg Arg Leu Lys Thr  Ser Leu Gly 
    1625                 1630                 1635             


Lys Val  Gly Val Lys Glu Glu  Leu Leu Ala Val Gly  Lys Leu Thr 
    1640                 1645                 1650             


Gln Thr  Ser Gly Glu Thr Thr  His Thr His Thr Glu  Pro Thr Gly 
    1655                 1660                 1665             


Asp Gly  Lys Ser Met Lys Ala  Phe Met Glu Ser Pro  Lys Gln Ile 
    1670                 1675                 1680             


Leu Asp  Ser Ala Ala Ser Leu  Thr Gly Ser Lys Arg  Gln Leu Arg 
    1685                 1690                 1695             


Thr Pro  Lys Gly Lys Ser Glu  Val Pro Glu Asp Leu  Ala Gly Phe 
    1700                 1705                 1710             


Ile Glu  Leu Phe Gln Thr Pro  Ser His Thr Lys Glu  Ser Met Thr 
    1715                 1720                 1725             


Asn Glu  Lys Thr Thr Lys Val  Ser Tyr Arg Ala Ser  Gln Pro Asp 
    1730                 1735                 1740             


Leu Val  Asp Thr Pro Thr Ser  Ser Lys Pro Gln Pro  Lys Arg Ser 
    1745                 1750                 1755             


Leu Arg  Lys Ala Asp Thr Glu  Glu Glu Phe Leu Ala  Phe Arg Lys 
    1760                 1765                 1770             


Gln Thr  Pro Ser Ala Gly Lys  Ala Met His Thr Pro  Lys Pro Ala 
    1775                 1780                 1785             


Val Gly  Glu Glu Lys Asp Ile  Asn Thr Phe Leu Gly  Thr Pro Val 
    1790                 1795                 1800             


Gln Lys  Leu Asp Gln Pro Gly  Asn Leu Pro Gly Ser  Asn Arg Arg 
    1805                 1810                 1815             


Leu Gln  Thr Arg Lys Glu Lys  Ala Gln Ala Leu Glu  Glu Leu Thr 
    1820                 1825                 1830             


Gly Phe  Arg Glu Leu Phe Gln  Thr Pro Cys Thr Asp  Asn Pro Thr 
    1835                 1840                 1845             


Thr Asp  Glu Lys Thr Thr Lys  Lys Ile Leu Cys Lys  Ser Pro Gln 
    1850                 1855                 1860             


Ser Asp  Pro Ala Asp Thr Pro  Thr Asn Thr Lys Gln  Arg Pro Lys 
    1865                 1870                 1875             


Arg Ser  Leu Lys Lys Ala Asp  Val Glu Glu Glu Phe  Leu Ala Phe 
    1880                 1885                 1890             


Arg Lys  Leu Thr Pro Ser Ala  Gly Lys Ala Met His  Thr Pro Lys 
    1895                 1900                 1905             


Ala Ala  Val Gly Glu Glu Lys  Asp Ile Asn Thr Phe  Val Gly Thr 
    1910                 1915                 1920             


Pro Val  Glu Lys Leu Asp Leu  Leu Gly Asn Leu Pro  Gly Ser Lys 
    1925                 1930                 1935             


Arg Arg  Pro Gln Thr Pro Lys  Glu Lys Ala Lys Ala  Leu Glu Asp 
    1940                 1945                 1950             


Leu Ala  Gly Phe Lys Glu Leu  Phe Gln Thr Pro Gly  His Thr Glu 
    1955                 1960                 1965             


Glu Ser  Met Thr Asp Asp Lys  Ile Thr Glu Val Ser  Cys Lys Ser 
    1970                 1975                 1980             


Pro Gln  Pro Asp Pro Val Lys  Thr Pro Thr Ser Ser  Lys Gln Arg 
    1985                 1990                 1995             


Leu Lys  Ile Ser Leu Gly Lys  Val Gly Val Lys Glu  Glu Val Leu 
    2000                 2005                 2010             


Pro Val  Gly Lys Leu Thr Gln  Thr Ser Gly Lys Thr  Thr Gln Thr 
    2015                 2020                 2025             


His Arg  Glu Thr Ala Gly Asp  Gly Lys Ser Ile Lys  Ala Phe Lys 
    2030                 2035                 2040             


Glu Ser  Ala Lys Gln Met Leu  Asp Pro Ala Asn Tyr  Gly Thr Gly 
    2045                 2050                 2055             


Met Glu  Arg Trp Pro Arg Thr  Pro Lys Glu Glu Ala  Gln Ser Leu 
    2060                 2065                 2070             


Glu Asp  Leu Ala Gly Phe Lys  Glu Leu Phe Gln Thr  Pro Asp His 
    2075                 2080                 2085             


Thr Glu  Glu Ser Thr Thr Asp  Asp Lys Thr Thr Lys  Ile Ala Cys 
    2090                 2095                 2100             


Lys Ser  Pro Pro Pro Glu Ser  Met Asp Thr Pro Thr  Ser Thr Arg 
    2105                 2110                 2115             


Arg Arg  Pro Lys Thr Pro Leu  Gly Lys Arg Asp Ile  Val Glu Glu 
    2120                 2125                 2130             


Leu Ser  Ala Leu Lys Gln Leu  Thr Gln Thr Thr His  Thr Asp Lys 
    2135                 2140                 2145             


Val Pro  Gly Asp Glu Asp Lys  Gly Ile Asn Val Phe  Arg Glu Thr 
    2150                 2155                 2160             


Ala Lys  Gln Lys Leu Asp Pro  Ala Ala Ser Val Thr  Gly Ser Lys 
    2165                 2170                 2175             


Arg Gln  Pro Arg Thr Pro Lys  Gly Lys Ala Gln Pro  Leu Glu Asp 
    2180                 2185                 2190             


Leu Ala  Gly Leu Lys Glu Leu  Phe Gln Thr Pro Ile  Cys Thr Asp 
    2195                 2200                 2205             


Lys Pro  Thr Thr His Glu Lys  Thr Thr Lys Ile Ala  Cys Arg Ser 
    2210                 2215                 2220             


Pro Gln  Pro Asp Pro Val Gly  Thr Pro Thr Ile Phe  Lys Pro Gln 
    2225                 2230                 2235             


Ser Lys  Arg Ser Leu Arg Lys  Ala Asp Val Glu Glu  Glu Ser Leu 
    2240                 2245                 2250             


Ala Leu  Arg Lys Arg Thr Pro  Ser Val Gly Lys Ala  Met Asp Thr 
    2255                 2260                 2265             


Pro Lys  Pro Ala Gly Gly Asp  Glu Lys Asp Met Lys  Ala Phe Met 
    2270                 2275                 2280             


Gly Thr  Pro Val Gln Lys Leu  Asp Leu Pro Gly Asn  Leu Pro Gly 
    2285                 2290                 2295             


Ser Lys  Arg Trp Pro Gln Thr  Pro Lys Glu Lys Ala  Gln Ala Leu 
    2300                 2305                 2310             


Glu Asp  Leu Ala Gly Phe Lys  Glu Leu Phe Gln Thr  Pro Gly Thr 
    2315                 2320                 2325             


Asp Lys  Pro Thr Thr Asp Glu  Lys Thr Thr Lys Ile  Ala Cys Lys 
    2330                 2335                 2340             


Ser Pro  Gln Pro Asp Pro Val  Asp Thr Pro Ala Ser  Thr Lys Gln 
    2345                 2350                 2355             


Arg Pro  Lys Arg Asn Leu Arg  Lys Ala Asp Val Glu  Glu Glu Phe 
    2360                 2365                 2370             


Leu Ala  Leu Arg Lys Arg Thr  Pro Ser Ala Gly Lys  Ala Met Asp 
    2375                 2380                 2385             


Thr Pro  Lys Pro Ala Val Ser  Asp Glu Lys Asn Ile  Asn Thr Phe 
    2390                 2395                 2400             


Val Glu  Thr Pro Val Gln Lys  Leu Asp Leu Leu Gly  Asn Leu Pro 
    2405                 2410                 2415             


Gly Ser  Lys Arg Gln Pro Gln  Thr Pro Lys Glu Lys  Ala Glu Ala 
    2420                 2425                 2430             


Leu Glu  Asp Leu Val Gly Phe  Lys Glu Leu Phe Gln  Thr Pro Gly 
    2435                 2440                 2445             


His Thr  Glu Glu Ser Met Thr  Asp Asp Lys Ile Thr  Glu Val Ser 
    2450                 2455                 2460             


Cys Lys  Ser Pro Gln Pro Glu  Ser Phe Lys Thr Ser  Arg Ser Ser 
    2465                 2470                 2475             


Lys Gln  Arg Leu Lys Ile Pro  Leu Val Lys Val Asp  Met Lys Glu 
    2480                 2485                 2490             


Glu Pro  Leu Ala Val Ser Lys  Leu Thr Arg Thr Ser  Gly Glu Thr 
    2495                 2500                 2505             


Thr Gln  Thr His Thr Glu Pro  Thr Gly Asp Ser Lys  Ser Ile Lys 
    2510                 2515                 2520             


Ala Phe  Lys Glu Ser Pro Lys  Gln Ile Leu Asp Pro  Ala Ala Ser 
    2525                 2530                 2535             


Val Thr  Gly Ser Arg Arg Gln  Leu Arg Thr Arg Lys  Glu Lys Ala 
    2540                 2545                 2550             


Arg Ala  Leu Glu Asp Leu Val  Asp Phe Lys Glu Leu  Phe Ser Ala 
    2555                 2560                 2565             


Pro Gly  His Thr Glu Glu Ser  Met Thr Ile Asp Lys  Asn Thr Lys 
    2570                 2575                 2580             


Ile Pro  Cys Lys Ser Pro Pro  Pro Glu Leu Thr Asp  Thr Ala Thr 
    2585                 2590                 2595             


Ser Thr  Lys Arg Cys Pro Lys  Thr Arg Pro Arg Lys  Glu Val Lys 
    2600                 2605                 2610             


Glu Glu  Leu Ser Ala Val Glu  Arg Leu Thr Gln Thr  Ser Gly Gln 
    2615                 2620                 2625             


Ser Thr  His Thr His Lys Glu  Pro Ala Ser Gly Asp  Glu Gly Ile 
    2630                 2635                 2640             


Lys Val  Leu Lys Gln Arg Ala  Lys Lys Lys Pro Asn  Pro Val Glu 
    2645                 2650                 2655             


Glu Glu  Pro Ser Arg Arg Arg  Pro Arg Ala Pro Lys  Glu Lys Ala 
    2660                 2665                 2670             


Gln Pro  Leu Glu Asp Leu Ala  Gly Phe Thr Glu Leu  Ser Glu Thr 
    2675                 2680                 2685             


Ser Gly  His Thr Gln Glu Ser  Leu Thr Ala Gly Lys  Ala Thr Lys 
    2690                 2695                 2700             


Ile Pro  Cys Glu Ser Pro Pro  Leu Glu Val Val Asp  Thr Thr Ala 
    2705                 2710                 2715             


Ser Thr  Lys Arg His Leu Arg  Thr Arg Val Gln Lys  Val Gln Val 
    2720                 2725                 2730             


Lys Glu  Glu Pro Ser Ala Val  Lys Phe Thr Gln Thr  Ser Gly Glu 
    2735                 2740                 2745             


Thr Thr  Asp Ala Asp Lys Glu  Pro Ala Gly Glu Asp  Lys Gly Ile 
    2750                 2755                 2760             


Lys Ala  Leu Lys Glu Ser Ala  Lys Gln Thr Pro Ala  Pro Ala Ala 
    2765                 2770                 2775             


Ser Val  Thr Gly Ser Arg Arg  Arg Pro Arg Ala Pro  Arg Glu Ser 
    2780                 2785                 2790             


Ala Gln  Ala Ile Glu Asp Leu  Ala Gly Phe Lys Asp  Pro Ala Ala 
    2795                 2800                 2805             


Gly His  Thr Glu Glu Ser Met  Thr Asp Asp Lys Thr  Thr Lys Ile 
    2810                 2815                 2820             


Pro Cys  Lys Ser Ser Pro Glu  Leu Glu Asp Thr Ala  Thr Ser Ser 
    2825                 2830                 2835             


Lys Arg  Arg Pro Arg Thr Arg  Ala Gln Lys Val Glu  Val Lys Glu 
    2840                 2845                 2850             


Glu Leu  Leu Ala Val Gly Lys  Leu Thr Gln Thr Ser  Gly Glu Thr 
    2855                 2860                 2865             


Thr His  Thr Asp Lys Glu Pro  Val Gly Glu Gly Lys  Gly Thr Lys 
    2870                 2875                 2880             


Ala Phe  Lys Gln Pro Ala Lys  Arg Lys Leu Asp Ala  Glu Asp Val 
    2885                 2890                 2895             


Ile Gly  Ser Arg Arg Gln Pro  Arg Ala Pro Lys Glu  Lys Ala Gln 
    2900                 2905                 2910             


Pro Leu  Glu Asp Leu Ala Ser  Phe Gln Glu Leu Ser  Gln Thr Pro 
    2915                 2920                 2925             


Gly His  Thr Glu Glu Leu Ala  Asn Gly Ala Ala Asp  Ser Phe Thr 
    2930                 2935                 2940             


Ser Ala  Pro Lys Gln Thr Pro  Asp Ser Gly Lys Pro  Leu Lys Ile 
    2945                 2950                 2955             


Ser Arg  Arg Val Leu Arg Ala  Pro Lys Val Glu Pro  Val Gly Asp 
    2960                 2965                 2970             


Val Val  Ser Thr Arg Asp Pro  Val Lys Ser Gln Ser  Lys Ser Asn 
    2975                 2980                 2985             


Thr Ser  Leu Pro Pro Leu Pro  Phe Lys Arg Gly Gly  Gly Lys Asp 
    2990                 2995                 3000             


Gly Ser  Val Thr Gly Thr Lys  Arg Leu Arg Cys Met  Pro Ala Pro 
    3005                 3010                 3015             


Glu Glu  Ile Val Glu Glu Leu  Pro Ala Ser Lys Lys  Gln Arg Val 
    3020                 3025                 3030             


Ala Pro  Arg Ala Arg Gly Lys  Ser Ser Glu Pro Val  Val Ile Met 
    3035                 3040                 3045             


Lys Arg  Ser Leu Arg Thr Ser  Ala Lys Arg Ile Glu  Pro Ala Glu 
    3050                 3055                 3060             


Glu Leu  Asn Ser Asn Asp Met  Lys Thr Asn Lys Glu  Glu His Lys 
    3065                 3070                 3075             


Leu Gln  Asp Ser Val Pro Glu  Asn Lys Gly Ile Ser  Leu Arg Ser 
    3080                 3085                 3090             


Arg Arg  Gln Asn Lys Thr Glu  Ala Glu Gln Gln Ile  Thr Glu Val 
    3095                 3100                 3105             


Phe Val  Leu Ala Glu Arg Ile  Glu Ile Asn Arg Asn  Glu Lys Lys 
    3110                 3115                 3120             


Pro Met  Lys Thr Ser Pro Glu  Met Asp Ile Gln Asn  Pro Asp Asp 
    3125                 3130                 3135             


Gly Ala  Arg Lys Pro Ile Pro  Arg Asp Lys Val Thr  Glu Asn Lys 
    3140                 3145                 3150             


Arg Cys  Leu Arg Ser Ala Arg  Gln Asn Glu Ser Ser  Gln Pro Lys 
    3155                 3160                 3165             


Val Ala  Glu Glu Ser Gly Gly  Gln Lys Ser Ala Lys  Val Leu Met 
    3170                 3175                 3180             


Gln Asn  Gln Lys Gly Lys Gly  Glu Ala Gly Asn Ser  Asp Ser Met 
    3185                 3190                 3195             


Cys Leu  Arg Ser Arg Lys Thr  Lys Ser Gln Pro Ala  Ala Ser Thr 
    3200                 3205                 3210             


Leu Glu  Ser Lys Ser Val Gln  Arg Val Thr Arg Ser  Val Lys Arg 
    3215                 3220                 3225             


Cys Ala  Glu Asn Pro Lys Lys  Ala Glu Asp Asn Val  Cys Val Lys 
    3230                 3235                 3240             


Lys Ile  Arg Thr Arg Ser His  Arg Asp Ser Glu Asp  Ile 
    3245                 3250                 3255     


<210>  2723
<211>  2896
<212>  PRT
<213>  homo sapiens

<400>  2723

Met Trp Pro Thr Arg Arg Leu Val Thr Ile Lys Arg Ser Gly Val Asp 
1               5                   10                  15      


Gly Pro His Phe Pro Leu Ser Leu Ser Thr Cys Leu Phe Gly Arg Gly 
            20                  25                  30          


Ile Glu Cys Asp Ile Arg Ile Gln Leu Pro Val Val Ser Lys Gln His 
        35                  40                  45              


Cys Lys Ile Glu Ile His Glu Gln Glu Ala Ile Leu His Asn Phe Ser 
    50                  55                  60                  


Ser Thr Asn Pro Thr Gln Val Asn Gly Ser Val Ile Asp Glu Pro Val 
65                  70                  75                  80  


Arg Leu Lys His Gly Asp Val Ile Thr Ile Ile Asp Arg Ser Phe Arg 
                85                  90                  95      


Tyr Glu Asn Glu Ser Leu Gln Asn Gly Arg Lys Ser Thr Glu Phe Pro 
            100                 105                 110         


Arg Lys Ile Arg Glu Gln Glu Pro Ala Arg Arg Val Ser Arg Ser Ser 
        115                 120                 125             


Phe Ser Ser Asp Pro Asp Glu Ser Glu Gly Ile Pro Leu Lys Arg Arg 
    130                 135                 140                 


Arg Val Ser Phe Gly Gly His Leu Arg Pro Glu Leu Phe Asp Glu Asn 
145                 150                 155                 160 


Leu Pro Pro Asn Thr Pro Leu Lys Arg Gly Glu Ala Pro Thr Lys Arg 
                165                 170                 175     


Lys Ser Leu Val Met His Thr Pro Pro Val Leu Lys Lys Ile Ile Lys 
            180                 185                 190         


Glu Gln Pro Gln Pro Ser Gly Lys Gln Glu Ser Gly Ser Glu Ile His 
        195                 200                 205             


Val Glu Val Lys Ala Gln Ser Leu Val Ile Ser Pro Pro Ala Pro Ser 
    210                 215                 220                 


Pro Arg Lys Thr Pro Val Ala Ser Asp Gln Arg Arg Arg Ser Cys Lys 
225                 230                 235                 240 


Thr Ala Pro Ala Ser Ser Ser Lys Ser Gln Thr Glu Val Pro Lys Arg 
                245                 250                 255     


Gly Gly Arg Lys Ser Gly Asn Leu Pro Ser Lys Arg Val Ser Ile Ser 
            260                 265                 270         


Arg Ser Gln His Asp Ile Leu Gln Met Ile Cys Ser Lys Arg Arg Ser 
        275                 280                 285             


Gly Ala Ser Glu Ala Asn Leu Ile Val Ala Lys Ser Trp Ala Asp Val 
    290                 295                 300                 


Val Lys Leu Gly Ala Lys Gln Thr Gln Thr Lys Val Ile Lys His Gly 
305                 310                 315                 320 


Pro Gln Arg Ser Met Asn Lys Arg Gln Arg Arg Pro Ala Thr Pro Lys 
                325                 330                 335     


Lys Pro Val Gly Glu Val His Ser Gln Phe Ser Thr Gly His Ala Asn 
            340                 345                 350         


Ser Pro Cys Thr Ile Ile Ile Gly Lys Ala His Thr Glu Lys Val His 
        355                 360                 365             


Val Pro Ala Arg Pro Tyr Arg Val Leu Asn Asn Phe Ile Ser Asn Gln 
    370                 375                 380                 


Lys Met Asp Phe Lys Glu Asp Leu Ser Gly Ile Ala Glu Met Phe Lys 
385                 390                 395                 400 


Thr Pro Val Lys Glu Gln Pro Gln Leu Thr Ser Thr Cys His Ile Ala 
                405                 410                 415     


Ile Ser Asn Ser Glu Asn Leu Leu Gly Lys Gln Phe Gln Gly Thr Asp 
            420                 425                 430         


Ser Gly Glu Glu Pro Leu Leu Pro Thr Ser Glu Ser Phe Gly Gly Asn 
        435                 440                 445             


Val Phe Phe Ser Ala Gln Asn Ala Ala Lys Gln Pro Ser Asp Lys Cys 
    450                 455                 460                 


Ser Ala Ser Pro Pro Leu Arg Arg Gln Cys Ile Arg Glu Asn Gly Asn 
465                 470                 475                 480 


Val Ala Lys Thr Pro Arg Asn Thr Tyr Lys Met Thr Ser Leu Glu Thr 
                485                 490                 495     


Lys Thr Ser Asp Thr Glu Thr Glu Pro Ser Lys Thr Val Ser Thr Ala 
            500                 505                 510         


Asn Arg Ser Gly Arg Ser Thr Glu Phe Arg Asn Ile Gln Lys Leu Pro 
        515                 520                 525             


Val Glu Ser Lys Ser Glu Glu Thr Asn Thr Glu Ile Val Glu Cys Ile 
    530                 535                 540                 


Leu Lys Arg Gly Gln Lys Ala Thr Leu Leu Gln Gln Arg Arg Glu Gly 
545                 550                 555                 560 


Glu Met Lys Glu Ile Glu Arg Pro Phe Glu Thr Tyr Lys Glu Asn Ile 
                565                 570                 575     


Glu Leu Lys Glu Asn Asp Glu Lys Met Lys Ala Met Lys Arg Ser Arg 
            580                 585                 590         


Thr Trp Gly Gln Lys Cys Ala Pro Met Ser Asp Leu Thr Asp Leu Lys 
        595                 600                 605             


Ser Leu Pro Asp Thr Glu Leu Met Lys Asp Thr Ala Arg Gly Gln Asn 
    610                 615                 620                 


Leu Leu Gln Thr Gln Asp His Ala Lys Ala Pro Lys Ser Glu Lys Gly 
625                 630                 635                 640 


Lys Ile Thr Lys Met Pro Cys Gln Ser Leu Gln Pro Glu Pro Ile Asn 
                645                 650                 655     


Thr Pro Thr His Thr Lys Gln Gln Leu Lys Ala Ser Leu Gly Lys Val 
            660                 665                 670         


Gly Val Lys Glu Glu Leu Leu Ala Val Gly Lys Phe Thr Arg Thr Ser 
        675                 680                 685             


Gly Glu Thr Thr His Thr His Arg Glu Pro Ala Gly Asp Gly Lys Ser 
    690                 695                 700                 


Ile Arg Thr Phe Lys Glu Ser Pro Lys Gln Ile Leu Asp Pro Ala Ala 
705                 710                 715                 720 


Arg Val Thr Gly Met Lys Lys Trp Pro Arg Thr Pro Lys Glu Glu Ala 
                725                 730                 735     


Gln Ser Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln Thr Pro 
            740                 745                 750         


Gly Pro Ser Glu Glu Ser Met Thr Asp Glu Lys Thr Thr Lys Ile Ala 
        755                 760                 765             


Cys Lys Ser Pro Pro Pro Glu Ser Val Asp Thr Pro Thr Ser Thr Lys 
    770                 775                 780                 


Gln Trp Pro Lys Arg Ser Leu Arg Lys Ala Asp Val Glu Glu Glu Phe 
785                 790                 795                 800 


Leu Ala Leu Arg Lys Leu Thr Pro Ser Ala Gly Lys Ala Met Leu Thr 
                805                 810                 815     


Pro Lys Pro Ala Gly Gly Asp Glu Lys Asp Ile Lys Ala Phe Met Gly 
            820                 825                 830         


Thr Pro Val Gln Lys Leu Asp Leu Ala Gly Thr Leu Pro Gly Ser Lys 
        835                 840                 845             


Arg Gln Leu Gln Thr Pro Lys Glu Lys Ala Gln Ala Leu Glu Asp Leu 
    850                 855                 860                 


Ala Gly Phe Lys Glu Leu Phe Gln Thr Pro Gly His Thr Glu Glu Leu 
865                 870                 875                 880 


Val Ala Ala Gly Lys Thr Thr Lys Ile Pro Cys Asp Ser Pro Gln Ser 
                885                 890                 895     


Asp Pro Val Asp Thr Pro Thr Ser Thr Lys Gln Arg Pro Lys Arg Ser 
            900                 905                 910         


Ile Arg Lys Ala Asp Val Glu Gly Glu Leu Leu Ala Cys Arg Asn Leu 
        915                 920                 925             


Met Pro Ser Ala Gly Lys Ala Met His Thr Pro Lys Pro Ser Val Gly 
    930                 935                 940                 


Glu Glu Lys Asp Ile Ile Ile Phe Val Gly Thr Pro Val Gln Lys Leu 
945                 950                 955                 960 


Asp Leu Thr Glu Asn Leu Thr Gly Ser Lys Arg Arg Pro Gln Thr Pro 
                965                 970                 975     


Lys Glu Glu Ala Gln Ala Leu Glu Asp Leu Thr Gly Phe Lys Glu Leu 
            980                 985                 990         


Phe Gln Thr Pro Gly His Thr Glu  Glu Ala Val Ala Ala  Gly Lys Thr 
        995                 1000                 1005             


Thr Lys  Met Pro Cys Glu Ser  Ser Pro Pro Glu Ser  Ala Asp Thr 
    1010                 1015                 1020             


Pro Thr  Ser Thr Arg Arg Gln  Pro Lys Thr Pro Leu  Glu Lys Arg 
    1025                 1030                 1035             


Asp Val  Gln Lys Glu Leu Ser  Ala Leu Lys Lys Leu  Thr Gln Thr 
    1040                 1045                 1050             


Ser Gly  Glu Thr Thr His Thr  Asp Lys Val Pro Gly  Gly Glu Asp 
    1055                 1060                 1065             


Lys Ser  Ile Asn Ala Phe Arg  Glu Thr Ala Lys Gln  Lys Leu Asp 
    1070                 1075                 1080             


Pro Ala  Ala Ser Val Thr Gly  Ser Lys Arg His Pro  Lys Thr Lys 
    1085                 1090                 1095             


Glu Lys  Ala Gln Pro Leu Glu  Asp Leu Ala Gly Leu  Lys Glu Leu 
    1100                 1105                 1110             


Phe Gln  Thr Pro Val Cys Thr  Asp Lys Pro Thr Thr  His Glu Lys 
    1115                 1120                 1125             


Thr Thr  Lys Ile Ala Cys Arg  Ser Gln Pro Asp Pro  Val Asp Thr 
    1130                 1135                 1140             


Pro Thr  Ser Ser Lys Pro Gln  Ser Lys Arg Ser Leu  Arg Lys Val 
    1145                 1150                 1155             


Asp Val  Glu Glu Glu Phe Phe  Ala Leu Arg Lys Arg  Thr Pro Ser 
    1160                 1165                 1170             


Ala Gly  Lys Ala Met His Thr  Pro Lys Pro Ala Val  Ser Gly Glu 
    1175                 1180                 1185             


Lys Asn  Ile Tyr Ala Phe Met  Gly Thr Pro Val Gln  Lys Leu Asp 
    1190                 1195                 1200             


Leu Thr  Glu Asn Leu Thr Gly  Ser Lys Arg Arg Leu  Gln Thr Pro 
    1205                 1210                 1215             


Lys Glu  Lys Ala Gln Ala Leu  Glu Asp Leu Ala Gly  Phe Lys Glu 
    1220                 1225                 1230             


Leu Phe  Gln Thr Arg Gly His  Thr Glu Glu Ser Met  Thr Asn Asp 
    1235                 1240                 1245             


Lys Thr  Ala Lys Val Ala Cys  Lys Ser Ser Gln Pro  Asp Pro Asp 
    1250                 1255                 1260             


Lys Asn  Pro Ala Ser Ser Lys  Arg Arg Leu Lys Thr  Ser Leu Gly 
    1265                 1270                 1275             


Lys Val  Gly Val Lys Glu Glu  Leu Leu Ala Val Gly  Lys Leu Thr 
    1280                 1285                 1290             


Gln Thr  Ser Gly Glu Thr Thr  His Thr His Thr Glu  Pro Thr Gly 
    1295                 1300                 1305             


Asp Gly  Lys Ser Met Lys Ala  Phe Met Glu Ser Pro  Lys Gln Ile 
    1310                 1315                 1320             


Leu Asp  Ser Ala Ala Ser Leu  Thr Gly Ser Lys Arg  Gln Leu Arg 
    1325                 1330                 1335             


Thr Pro  Lys Gly Lys Ser Glu  Val Pro Glu Asp Leu  Ala Gly Phe 
    1340                 1345                 1350             


Ile Glu  Leu Phe Gln Thr Pro  Ser His Thr Lys Glu  Ser Met Thr 
    1355                 1360                 1365             


Asn Glu  Lys Thr Thr Lys Val  Ser Tyr Arg Ala Ser  Gln Pro Asp 
    1370                 1375                 1380             


Leu Val  Asp Thr Pro Thr Ser  Ser Lys Pro Gln Pro  Lys Arg Ser 
    1385                 1390                 1395             


Leu Arg  Lys Ala Asp Thr Glu  Glu Glu Phe Leu Ala  Phe Arg Lys 
    1400                 1405                 1410             


Gln Thr  Pro Ser Ala Gly Lys  Ala Met His Thr Pro  Lys Pro Ala 
    1415                 1420                 1425             


Val Gly  Glu Glu Lys Asp Ile  Asn Thr Phe Leu Gly  Thr Pro Val 
    1430                 1435                 1440             


Gln Lys  Leu Asp Gln Pro Gly  Asn Leu Pro Gly Ser  Asn Arg Arg 
    1445                 1450                 1455             


Leu Gln  Thr Arg Lys Glu Lys  Ala Gln Ala Leu Glu  Glu Leu Thr 
    1460                 1465                 1470             


Gly Phe  Arg Glu Leu Phe Gln  Thr Pro Cys Thr Asp  Asn Pro Thr 
    1475                 1480                 1485             


Thr Asp  Glu Lys Thr Thr Lys  Lys Ile Leu Cys Lys  Ser Pro Gln 
    1490                 1495                 1500             


Ser Asp  Pro Ala Asp Thr Pro  Thr Asn Thr Lys Gln  Arg Pro Lys 
    1505                 1510                 1515             


Arg Ser  Leu Lys Lys Ala Asp  Val Glu Glu Glu Phe  Leu Ala Phe 
    1520                 1525                 1530             


Arg Lys  Leu Thr Pro Ser Ala  Gly Lys Ala Met His  Thr Pro Lys 
    1535                 1540                 1545             


Ala Ala  Val Gly Glu Glu Lys  Asp Ile Asn Thr Phe  Val Gly Thr 
    1550                 1555                 1560             


Pro Val  Glu Lys Leu Asp Leu  Leu Gly Asn Leu Pro  Gly Ser Lys 
    1565                 1570                 1575             


Arg Arg  Pro Gln Thr Pro Lys  Glu Lys Ala Lys Ala  Leu Glu Asp 
    1580                 1585                 1590             


Leu Ala  Gly Phe Lys Glu Leu  Phe Gln Thr Pro Gly  His Thr Glu 
    1595                 1600                 1605             


Glu Ser  Met Thr Asp Asp Lys  Ile Thr Glu Val Ser  Cys Lys Ser 
    1610                 1615                 1620             


Pro Gln  Pro Asp Pro Val Lys  Thr Pro Thr Ser Ser  Lys Gln Arg 
    1625                 1630                 1635             


Leu Lys  Ile Ser Leu Gly Lys  Val Gly Val Lys Glu  Glu Val Leu 
    1640                 1645                 1650             


Pro Val  Gly Lys Leu Thr Gln  Thr Ser Gly Lys Thr  Thr Gln Thr 
    1655                 1660                 1665             


His Arg  Glu Thr Ala Gly Asp  Gly Lys Ser Ile Lys  Ala Phe Lys 
    1670                 1675                 1680             


Glu Ser  Ala Lys Gln Met Leu  Asp Pro Ala Asn Tyr  Gly Thr Gly 
    1685                 1690                 1695             


Met Glu  Arg Trp Pro Arg Thr  Pro Lys Glu Glu Ala  Gln Ser Leu 
    1700                 1705                 1710             


Glu Asp  Leu Ala Gly Phe Lys  Glu Leu Phe Gln Thr  Pro Asp His 
    1715                 1720                 1725             


Thr Glu  Glu Ser Thr Thr Asp  Asp Lys Thr Thr Lys  Ile Ala Cys 
    1730                 1735                 1740             


Lys Ser  Pro Pro Pro Glu Ser  Met Asp Thr Pro Thr  Ser Thr Arg 
    1745                 1750                 1755             


Arg Arg  Pro Lys Thr Pro Leu  Gly Lys Arg Asp Ile  Val Glu Glu 
    1760                 1765                 1770             


Leu Ser  Ala Leu Lys Gln Leu  Thr Gln Thr Thr His  Thr Asp Lys 
    1775                 1780                 1785             


Val Pro  Gly Asp Glu Asp Lys  Gly Ile Asn Val Phe  Arg Glu Thr 
    1790                 1795                 1800             


Ala Lys  Gln Lys Leu Asp Pro  Ala Ala Ser Val Thr  Gly Ser Lys 
    1805                 1810                 1815             


Arg Gln  Pro Arg Thr Pro Lys  Gly Lys Ala Gln Pro  Leu Glu Asp 
    1820                 1825                 1830             


Leu Ala  Gly Leu Lys Glu Leu  Phe Gln Thr Pro Ile  Cys Thr Asp 
    1835                 1840                 1845             


Lys Pro  Thr Thr His Glu Lys  Thr Thr Lys Ile Ala  Cys Arg Ser 
    1850                 1855                 1860             


Pro Gln  Pro Asp Pro Val Gly  Thr Pro Thr Ile Phe  Lys Pro Gln 
    1865                 1870                 1875             


Ser Lys  Arg Ser Leu Arg Lys  Ala Asp Val Glu Glu  Glu Ser Leu 
    1880                 1885                 1890             


Ala Leu  Arg Lys Arg Thr Pro  Ser Val Gly Lys Ala  Met Asp Thr 
    1895                 1900                 1905             


Pro Lys  Pro Ala Gly Gly Asp  Glu Lys Asp Met Lys  Ala Phe Met 
    1910                 1915                 1920             


Gly Thr  Pro Val Gln Lys Leu  Asp Leu Pro Gly Asn  Leu Pro Gly 
    1925                 1930                 1935             


Ser Lys  Arg Trp Pro Gln Thr  Pro Lys Glu Lys Ala  Gln Ala Leu 
    1940                 1945                 1950             


Glu Asp  Leu Ala Gly Phe Lys  Glu Leu Phe Gln Thr  Pro Gly Thr 
    1955                 1960                 1965             


Asp Lys  Pro Thr Thr Asp Glu  Lys Thr Thr Lys Ile  Ala Cys Lys 
    1970                 1975                 1980             


Ser Pro  Gln Pro Asp Pro Val  Asp Thr Pro Ala Ser  Thr Lys Gln 
    1985                 1990                 1995             


Arg Pro  Lys Arg Asn Leu Arg  Lys Ala Asp Val Glu  Glu Glu Phe 
    2000                 2005                 2010             


Leu Ala  Leu Arg Lys Arg Thr  Pro Ser Ala Gly Lys  Ala Met Asp 
    2015                 2020                 2025             


Thr Pro  Lys Pro Ala Val Ser  Asp Glu Lys Asn Ile  Asn Thr Phe 
    2030                 2035                 2040             


Val Glu  Thr Pro Val Gln Lys  Leu Asp Leu Leu Gly  Asn Leu Pro 
    2045                 2050                 2055             


Gly Ser  Lys Arg Gln Pro Gln  Thr Pro Lys Glu Lys  Ala Glu Ala 
    2060                 2065                 2070             


Leu Glu  Asp Leu Val Gly Phe  Lys Glu Leu Phe Gln  Thr Pro Gly 
    2075                 2080                 2085             


His Thr  Glu Glu Ser Met Thr  Asp Asp Lys Ile Thr  Glu Val Ser 
    2090                 2095                 2100             


Cys Lys  Ser Pro Gln Pro Glu  Ser Phe Lys Thr Ser  Arg Ser Ser 
    2105                 2110                 2115             


Lys Gln  Arg Leu Lys Ile Pro  Leu Val Lys Val Asp  Met Lys Glu 
    2120                 2125                 2130             


Glu Pro  Leu Ala Val Ser Lys  Leu Thr Arg Thr Ser  Gly Glu Thr 
    2135                 2140                 2145             


Thr Gln  Thr His Thr Glu Pro  Thr Gly Asp Ser Lys  Ser Ile Lys 
    2150                 2155                 2160             


Ala Phe  Lys Glu Ser Pro Lys  Gln Ile Leu Asp Pro  Ala Ala Ser 
    2165                 2170                 2175             


Val Thr  Gly Ser Arg Arg Gln  Leu Arg Thr Arg Lys  Glu Lys Ala 
    2180                 2185                 2190             


Arg Ala  Leu Glu Asp Leu Val  Asp Phe Lys Glu Leu  Phe Ser Ala 
    2195                 2200                 2205             


Pro Gly  His Thr Glu Glu Ser  Met Thr Ile Asp Lys  Asn Thr Lys 
    2210                 2215                 2220             


Ile Pro  Cys Lys Ser Pro Pro  Pro Glu Leu Thr Asp  Thr Ala Thr 
    2225                 2230                 2235             


Ser Thr  Lys Arg Cys Pro Lys  Thr Arg Pro Arg Lys  Glu Val Lys 
    2240                 2245                 2250             


Glu Glu  Leu Ser Ala Val Glu  Arg Leu Thr Gln Thr  Ser Gly Gln 
    2255                 2260                 2265             


Ser Thr  His Thr His Lys Glu  Pro Ala Ser Gly Asp  Glu Gly Ile 
    2270                 2275                 2280             


Lys Val  Leu Lys Gln Arg Ala  Lys Lys Lys Pro Asn  Pro Val Glu 
    2285                 2290                 2295             


Glu Glu  Pro Ser Arg Arg Arg  Pro Arg Ala Pro Lys  Glu Lys Ala 
    2300                 2305                 2310             


Gln Pro  Leu Glu Asp Leu Ala  Gly Phe Thr Glu Leu  Ser Glu Thr 
    2315                 2320                 2325             


Ser Gly  His Thr Gln Glu Ser  Leu Thr Ala Gly Lys  Ala Thr Lys 
    2330                 2335                 2340             


Ile Pro  Cys Glu Ser Pro Pro  Leu Glu Val Val Asp  Thr Thr Ala 
    2345                 2350                 2355             


Ser Thr  Lys Arg His Leu Arg  Thr Arg Val Gln Lys  Val Gln Val 
    2360                 2365                 2370             


Lys Glu  Glu Pro Ser Ala Val  Lys Phe Thr Gln Thr  Ser Gly Glu 
    2375                 2380                 2385             


Thr Thr  Asp Ala Asp Lys Glu  Pro Ala Gly Glu Asp  Lys Gly Ile 
    2390                 2395                 2400             


Lys Ala  Leu Lys Glu Ser Ala  Lys Gln Thr Pro Ala  Pro Ala Ala 
    2405                 2410                 2415             


Ser Val  Thr Gly Ser Arg Arg  Arg Pro Arg Ala Pro  Arg Glu Ser 
    2420                 2425                 2430             


Ala Gln  Ala Ile Glu Asp Leu  Ala Gly Phe Lys Asp  Pro Ala Ala 
    2435                 2440                 2445             


Gly His  Thr Glu Glu Ser Met  Thr Asp Asp Lys Thr  Thr Lys Ile 
    2450                 2455                 2460             


Pro Cys  Lys Ser Ser Pro Glu  Leu Glu Asp Thr Ala  Thr Ser Ser 
    2465                 2470                 2475             


Lys Arg  Arg Pro Arg Thr Arg  Ala Gln Lys Val Glu  Val Lys Glu 
    2480                 2485                 2490             


Glu Leu  Leu Ala Val Gly Lys  Leu Thr Gln Thr Ser  Gly Glu Thr 
    2495                 2500                 2505             


Thr His  Thr Asp Lys Glu Pro  Val Gly Glu Gly Lys  Gly Thr Lys 
    2510                 2515                 2520             


Ala Phe  Lys Gln Pro Ala Lys  Arg Lys Leu Asp Ala  Glu Asp Val 
    2525                 2530                 2535             


Ile Gly  Ser Arg Arg Gln Pro  Arg Ala Pro Lys Glu  Lys Ala Gln 
    2540                 2545                 2550             


Pro Leu  Glu Asp Leu Ala Ser  Phe Gln Glu Leu Ser  Gln Thr Pro 
    2555                 2560                 2565             


Gly His  Thr Glu Glu Leu Ala  Asn Gly Ala Ala Asp  Ser Phe Thr 
    2570                 2575                 2580             


Ser Ala  Pro Lys Gln Thr Pro  Asp Ser Gly Lys Pro  Leu Lys Ile 
    2585                 2590                 2595             


Ser Arg  Arg Val Leu Arg Ala  Pro Lys Val Glu Pro  Val Gly Asp 
    2600                 2605                 2610             


Val Val  Ser Thr Arg Asp Pro  Val Lys Ser Gln Ser  Lys Ser Asn 
    2615                 2620                 2625             


Thr Ser  Leu Pro Pro Leu Pro  Phe Lys Arg Gly Gly  Gly Lys Asp 
    2630                 2635                 2640             


Gly Ser  Val Thr Gly Thr Lys  Arg Leu Arg Cys Met  Pro Ala Pro 
    2645                 2650                 2655             


Glu Glu  Ile Val Glu Glu Leu  Pro Ala Ser Lys Lys  Gln Arg Val 
    2660                 2665                 2670             


Ala Pro  Arg Ala Arg Gly Lys  Ser Ser Glu Pro Val  Val Ile Met 
    2675                 2680                 2685             


Lys Arg  Ser Leu Arg Thr Ser  Ala Lys Arg Ile Glu  Pro Ala Glu 
    2690                 2695                 2700             


Glu Leu  Asn Ser Asn Asp Met  Lys Thr Asn Lys Glu  Glu His Lys 
    2705                 2710                 2715             


Leu Gln  Asp Ser Val Pro Glu  Asn Lys Gly Ile Ser  Leu Arg Ser 
    2720                 2725                 2730             


Arg Arg  Gln Asn Lys Thr Glu  Ala Glu Gln Gln Ile  Thr Glu Val 
    2735                 2740                 2745             


Phe Val  Leu Ala Glu Arg Ile  Glu Ile Asn Arg Asn  Glu Lys Lys 
    2750                 2755                 2760             


Pro Met  Lys Thr Ser Pro Glu  Met Asp Ile Gln Asn  Pro Asp Asp 
    2765                 2770                 2775             


Gly Ala  Arg Lys Pro Ile Pro  Arg Asp Lys Val Thr  Glu Asn Lys 
    2780                 2785                 2790             


Arg Cys  Leu Arg Ser Ala Arg  Gln Asn Glu Ser Ser  Gln Pro Lys 
    2795                 2800                 2805             


Val Ala  Glu Glu Ser Gly Gly  Gln Lys Ser Ala Lys  Val Leu Met 
    2810                 2815                 2820             


Gln Asn  Gln Lys Gly Lys Gly  Glu Ala Gly Asn Ser  Asp Ser Met 
    2825                 2830                 2835             


Cys Leu  Arg Ser Arg Lys Thr  Lys Ser Gln Pro Ala  Ala Ser Thr 
    2840                 2845                 2850             


Leu Glu  Ser Lys Ser Val Gln  Arg Val Thr Arg Ser  Val Lys Arg 
    2855                 2860                 2865             


Cys Ala  Glu Asn Pro Lys Lys  Ala Glu Asp Asn Val  Cys Val Lys 
    2870                 2875                 2880             


Lys Ile  Arg Thr Arg Ser His  Arg Asp Ser Glu Asp  Ile 
    2885                 2890                 2895     


<210>  2724
<211>  395
<212>  PRT
<213>  homo sapiens

<400>  2724

Met Ala Ser Val Pro Met Pro Ser Glu Tyr Thr Tyr Val Lys Leu Arg 
1               5                   10                  15      


Ser Asp Cys Ser Arg Pro Ser Leu Gln Trp Tyr Thr Arg Ala Gln Ser 
            20                  25                  30          


Lys Met Arg Arg Pro Ser Leu Leu Leu Lys Asp Ile Leu Lys Cys Thr 
        35                  40                  45              


Leu Leu Val Phe Gly Val Trp Ile Leu Tyr Ile Leu Lys Leu Asn Tyr 
    50                  55                  60                  


Thr Thr Glu Glu Cys Asp Met Lys Lys Met His Tyr Val Asp Pro Asp 
65                  70                  75                  80  


His Val Lys Arg Ala Gln Lys Tyr Ala Gln Gln Val Leu Gln Lys Glu 
                85                  90                  95      


Cys Arg Pro Lys Phe Ala Lys Thr Ser Met Ala Leu Leu Phe Glu His 
            100                 105                 110         


Arg Tyr Ser Val Asp Leu Leu Pro Phe Val Gln Lys Ala Pro Lys Asp 
        115                 120                 125             


Ser Glu Ala Glu Ser Lys Tyr Asp Pro Pro Phe Gly Phe Arg Lys Phe 
    130                 135                 140                 


Ser Ser Lys Val Gln Thr Leu Leu Glu Leu Leu Pro Glu His Asp Leu 
145                 150                 155                 160 


Pro Glu His Leu Lys Ala Lys Thr Cys Arg Arg Cys Val Val Ile Gly 
                165                 170                 175     


Ser Gly Gly Ile Leu His Gly Leu Glu Leu Gly His Thr Leu Asn Gln 
            180                 185                 190         


Phe Asp Val Val Ile Arg Leu Asn Ser Ala Pro Val Glu Gly Tyr Ser 
        195                 200                 205             


Glu His Val Gly Asn Lys Thr Thr Ile Arg Met Thr Tyr Pro Glu Gly 
    210                 215                 220                 


Ala Pro Leu Ser Asp Leu Glu Tyr Tyr Ser Asn Asp Leu Phe Val Ala 
225                 230                 235                 240 


Val Leu Phe Lys Ser Val Asp Phe Asn Trp Leu Gln Ala Met Val Lys 
                245                 250                 255     


Lys Glu Thr Leu Pro Phe Trp Val Arg Leu Phe Phe Trp Lys Gln Val 
            260                 265                 270         


Ala Glu Lys Ile Pro Leu Gln Pro Lys His Phe Arg Ile Leu Asn Pro 
        275                 280                 285             


Val Ile Ile Lys Glu Thr Ala Phe Asp Ile Leu Gln Tyr Ser Glu Pro 
    290                 295                 300                 


Gln Ser Arg Phe Trp Gly Arg Asp Lys Asn Val Pro Thr Ile Gly Val 
305                 310                 315                 320 


Ile Ala Val Val Leu Ala Thr His Leu Cys Asp Glu Val Ser Leu Ala 
                325                 330                 335     


Gly Phe Gly Tyr Asp Leu Asn Gln Pro Arg Thr Pro Leu His Tyr Phe 
            340                 345                 350         


Asp Ser Gln Cys Met Ala Ala Met Asn Phe Gln Thr Met His Asn Val 
        355                 360                 365             


Thr Thr Glu Thr Lys Phe Leu Leu Lys Leu Val Lys Glu Gly Val Val 
    370                 375                 380                 


Lys Asp Leu Ser Gly Gly Ile Asp Arg Glu Phe 
385                 390                 395 


<210>  2725
<211>  660
<212>  PRT
<213>  homo sapiens

<400>  2725

Met Val Gln Arg Asp Met Ser Lys Ser Pro Pro Thr Ala Ala Ala Ala 
1               5                   10                  15      


Val Ala Gln Glu Ile Gln Met Glu Leu Leu Glu Asn Val Ala Pro Ala 
            20                  25                  30          


Gly Ala Leu Gly Ala Ala Ala Gln Ser Tyr Gly Lys Gly Ala Arg Arg 
        35                  40                  45              


Lys Asn Arg Phe Lys Gly Ser Asp Gly Ser Thr Ser Ser Asp Thr Thr 
    50                  55                  60                  


Ser Asn Ser Phe Val Arg Gln Gly Ser Ala Asp Ser Tyr Thr Ser Arg 
65                  70                  75                  80  


Pro Ser Asp Ser Asp Val Ser Leu Glu Glu Asp Arg Glu Ala Val Arg 
                85                  90                  95      


Arg Glu Ala Glu Arg Gln Ala Gln Ala Gln Leu Glu Lys Ala Lys Thr 
            100                 105                 110         


Lys Pro Val Ala Phe Ala Val Arg Thr Asn Val Ser Tyr Ser Ala Ala 
        115                 120                 125             


His Glu Asp Asp Val Pro Val Pro Gly Met Ala Ile Ser Phe Glu Ala 
    130                 135                 140                 


Lys Asp Phe Leu His Val Lys Glu Lys Phe Asn Asn Asp Trp Trp Ile 
145                 150                 155                 160 


Gly Arg Leu Val Lys Glu Gly Cys Glu Ile Gly Phe Ile Pro Ser Pro 
                165                 170                 175     


Val Lys Leu Glu Asn Met Arg Leu Gln His Glu Gln Arg Ala Lys Gln 
            180                 185                 190         


Gly Lys Phe Tyr Ser Ser Lys Ser Gly Gly Asn Ser Ser Ser Ser Leu 
        195                 200                 205             


Gly Asp Ile Val Pro Ser Ser Arg Lys Ser Thr Pro Pro Ser Ser Ala 
    210                 215                 220                 


Ile Asp Ile Asp Ala Thr Gly Leu Asp Ala Glu Glu Asn Asp Ile Pro 
225                 230                 235                 240 


Ala Asn His Arg Ser Pro Lys Pro Ser Ala Asn Ser Val Thr Ser Pro 
                245                 250                 255     


His Ser Lys Glu Lys Arg Met Pro Phe Phe Lys Lys Thr Glu His Thr 
            260                 265                 270         


Pro Pro Tyr Asp Val Val Pro Ser Met Arg Pro Val Val Leu Val Gly 
        275                 280                 285             


Pro Ser Leu Lys Gly Tyr Glu Val Thr Asp Met Met Gln Lys Ala Leu 
    290                 295                 300                 


Phe Asp Phe Leu Lys His Arg Phe Glu Gly Arg Ile Ser Ile Thr Arg 
305                 310                 315                 320 


Val Thr Ala Asp Ile Ser Leu Ala Lys Arg Ser Val Leu Asn Asn Pro 
                325                 330                 335     


Ser Lys His Ala Ile Ile Glu Arg Ser Asn Thr Arg Ser Ser Leu Ala 
            340                 345                 350         


Glu Val Gln Ser Glu Ile Glu Arg Ile Phe Glu Leu Ala Arg Thr Leu 
        355                 360                 365             


Gln Leu Val Val Leu Asp Ala Asp Thr Ile Asn His Pro Ala Gln Leu 
    370                 375                 380                 


Ser Lys Thr Ser Leu Ala Pro Ile Ile Val Tyr Val Lys Ile Ser Ser 
385                 390                 395                 400 


Pro Lys Val Leu Gln Arg Leu Ile Lys Ser Arg Gly Lys Ser Gln Ala 
                405                 410                 415     


Lys His Leu Asn Val Gln Met Val Ala Ala Asp Lys Leu Ala Gln Cys 
            420                 425                 430         


Pro Pro Glu Leu Phe Asp Val Ile Leu Asp Glu Asn Gln Leu Glu Asp 
        435                 440                 445             


Ala Cys Glu His Leu Ala Asp Tyr Leu Glu Ala Tyr Trp Lys Ala Thr 
    450                 455                 460                 


His Pro Pro Ser Ser Ser Leu Pro Asn Pro Leu Leu Ser Arg Thr Leu 
465                 470                 475                 480 


Ala Thr Ser Ser Leu Pro Leu Ser Pro Thr Leu Ala Ser Asn Ser Gln 
                485                 490                 495     


Gly Ser Gln Gly Asp Gln Arg Thr Asp Arg Ser Ala Pro Ile Arg Ser 
            500                 505                 510         


Ala Ser Gln Ala Glu Glu Glu Pro Ser Val Glu Pro Val Lys Lys Ser 
        515                 520                 525             


Gln His Arg Ser Ser Ser Ser Ala Pro His His Asn His Arg Ser Gly 
    530                 535                 540                 


Thr Ser Arg Gly Leu Ser Arg Gln Glu Thr Phe Asp Ser Glu Thr Gln 
545                 550                 555                 560 


Glu Ser Arg Asp Ser Ala Tyr Val Glu Pro Lys Glu Asp Tyr Ser His 
                565                 570                 575     


Asp His Val Asp His Tyr Ala Ser His Arg Asp His Asn His Arg Asp 
            580                 585                 590         


Glu Thr His Gly Ser Ser Asp His Arg His Arg Glu Ser Arg His Arg 
        595                 600                 605             


Ser Arg Asp Val Asp Arg Glu Gln Asp His Asn Glu Cys Asn Lys Gln 
    610                 615                 620                 


Arg Ser Arg His Lys Ser Lys Asp Arg Tyr Cys Glu Lys Asp Gly Glu 
625                 630                 635                 640 


Val Ile Ser Lys Lys Arg Asn Glu Ala Gly Glu Trp Asn Arg Asp Val 
                645                 650                 655     


Tyr Ile Arg Gln 
            660 


<210>  2726
<211>  1101
<212>  PRT
<213>  homo sapiens

<400>  2726

Met Ala Thr Pro Ser Lys Lys Thr Ser Thr Pro Ser Pro Gln Pro Ser 
1               5                   10                  15      


Lys Arg Ala Leu Pro Arg Asp Pro Ser Ser Glu Val Pro Ser Lys Arg 
            20                  25                  30          


Lys Asn Ser Ala Pro Gln Leu Pro Leu Leu Gln Ser Ser Gly Pro Phe 
        35                  40                  45              


Val Glu Gly Ser Ile Val Arg Ile Ser Met Glu Asn Phe Leu Thr Tyr 
    50                  55                  60                  


Asp Ile Cys Glu Val Ser Pro Gly Pro His Leu Asn Met Ile Val Gly 
65                  70                  75                  80  


Ala Asn Gly Thr Gly Lys Ser Ser Ile Val Cys Ala Ile Cys Leu Gly 
                85                  90                  95      


Leu Ala Gly Lys Pro Ala Phe Met Gly Arg Ala Asp Lys Val Gly Phe 
            100                 105                 110         


Phe Val Lys Arg Gly Cys Ser Arg Gly Met Val Glu Ile Glu Leu Phe 
        115                 120                 125             


Arg Ala Ser Gly Asn Leu Val Ile Thr Arg Glu Ile Asp Val Ala Lys 
    130                 135                 140                 


Asn Gln Ser Phe Trp Phe Ile Asn Lys Lys Ser Thr Thr Gln Lys Ile 
145                 150                 155                 160 


Val Glu Glu Lys Val Ala Ala Leu Asn Ile Gln Val Gly Asn Leu Cys 
                165                 170                 175     


Gln Phe Leu Pro Gln Asp Lys Val Gly Glu Phe Ala Lys Leu Ser Lys 
            180                 185                 190         


Ile Glu Leu Leu Glu Ala Thr Glu Lys Ser Ile Gly Pro Pro Glu Met 
        195                 200                 205             


His Lys Tyr His Cys Glu Leu Lys Asn Leu Arg Glu Lys Glu Lys Gln 
    210                 215                 220                 


Leu Glu Thr Ser Cys Lys Glu Lys Thr Glu Tyr Leu Gln Lys Met Val 
225                 230                 235                 240 


Gln Arg Asn Glu Arg Tyr Lys Gln Asp Val Glu Arg Phe Tyr Glu Arg 
                245                 250                 255     


Lys Arg His Leu Asp Leu Ile Glu Met Leu Glu Ala Lys Arg Pro Trp 
            260                 265                 270         


Val Glu Tyr Glu Asn Val Arg Gln Glu Tyr Glu Glu Val Lys Leu Val 
        275                 280                 285             


Arg Asp Arg Val Lys Glu Glu Val Arg Lys Leu Lys Glu Gly Gln Ile 
    290                 295                 300                 


Pro Val Thr Cys Arg Ile Glu Glu Met Glu Asn Glu Arg His Asn Leu 
305                 310                 315                 320 


Glu Ala Arg Ile Lys Glu Lys Ala Thr Asp Ile Lys Glu Ala Ser Gln 
                325                 330                 335     


Lys Cys Lys Gln Lys Gln Asp Val Ile Glu Arg Lys Asp Lys His Ile 
            340                 345                 350         


Glu Glu Leu Gln Gln Ala Leu Ile Val Lys Gln Asn Glu Glu Leu Asp 
        355                 360                 365             


Arg Gln Arg Arg Ile Gly Asn Thr Arg Lys Met Ile Glu Asp Leu Gln 
    370                 375                 380                 


Asn Glu Leu Lys Thr Thr Glu Asn Cys Glu Asn Leu Gln Pro Gln Ile 
385                 390                 395                 400 


Asp Ala Ile Thr Asn Asp Leu Arg Arg Ile Gln Asp Glu Lys Ala Leu 
                405                 410                 415     


Cys Glu Gly Glu Ile Ile Asp Lys Arg Arg Glu Arg Glu Thr Leu Glu 
            420                 425                 430         


Lys Glu Lys Lys Ser Val Asp Asp His Ile Val Arg Phe Asp Asn Leu 
        435                 440                 445             


Met Asn Gln Lys Glu Asp Lys Leu Arg Gln Arg Phe Arg Asp Thr Tyr 
    450                 455                 460                 


Asp Ala Val Leu Trp Leu Arg Asn Asn Arg Asp Lys Phe Lys Gln Arg 
465                 470                 475                 480 


Val Cys Glu Pro Ile Met Leu Thr Ile Asn Met Lys Asp Asn Lys Asn 
                485                 490                 495     


Ala Lys Tyr Ile Glu Asn His Ile Pro Ser Asn Asp Leu Arg Ala Phe 
            500                 505                 510         


Val Phe Glu Ser Gln Glu Asp Met Glu Val Phe Leu Lys Glu Val Arg 
        515                 520                 525             


Asp Asn Lys Lys Leu Arg Val Asn Ala Val Ile Ala Pro Lys Ser Ser 
    530                 535                 540                 


Tyr Ala Asp Lys Ala Pro Ser Arg Ser Leu Asn Glu Leu Lys Gln Tyr 
545                 550                 555                 560 


Gly Phe Phe Ser Tyr Leu Arg Glu Leu Phe Asp Ala Pro Asp Pro Val 
                565                 570                 575     


Met Ser Tyr Leu Cys Cys Gln Tyr His Ile His Glu Val Pro Val Gly 
            580                 585                 590         


Thr Glu Lys Thr Arg Glu Arg Ile Glu Arg Val Ile Gln Glu Thr Arg 
        595                 600                 605             


Leu Lys Gln Ile Tyr Thr Ala Glu Glu Lys Tyr Val Val Lys Thr Ser 
    610                 615                 620                 


Phe Tyr Ser Asn Lys Val Ile Ser Ser Asn Thr Ser Leu Lys Val Ala 
625                 630                 635                 640 


Gln Phe Leu Thr Val Thr Val Asp Leu Glu Gln Arg Arg His Leu Glu 
                645                 650                 655     


Glu Gln Leu Lys Glu Ile His Arg Lys Leu Gln Ala Val Asp Ser Gly 
            660                 665                 670         


Leu Ile Ala Leu Arg Glu Thr Ser Lys His Leu Glu His Lys Asp Asn 
        675                 680                 685             


Glu Leu Arg Gln Lys Lys Lys Glu Leu Leu Glu Arg Lys Thr Lys Lys 
    690                 695                 700                 


Arg Gln Leu Glu Gln Lys Ile Ser Ser Lys Leu Gly Ser Leu Lys Leu 
705                 710                 715                 720 


Met Glu Gln Asp Thr Cys Asn Leu Glu Glu Glu Glu Arg Lys Ala Ser 
                725                 730                 735     


Thr Lys Ile Lys Glu Ile Asn Val Gln Lys Ala Lys Leu Val Thr Glu 
            740                 745                 750         


Leu Thr Asn Leu Ile Lys Ile Cys Thr Ser Leu His Ile Gln Lys Val 
        755                 760                 765             


Asp Leu Ile Leu Gln Asn Thr Thr Val Ile Ser Glu Lys Asn Lys Leu 
    770                 775                 780                 


Glu Ser Asp Tyr Met Ala Ala Ser Ser Gln Leu Arg Leu Thr Glu Gln 
785                 790                 795                 800 


His Phe Ile Glu Leu Asp Glu Asn Arg Gln Arg Leu Leu Gln Lys Cys 
                805                 810                 815     


Lys Glu Leu Met Lys Arg Ala Arg Gln Val Cys Asn Leu Gly Ala Glu 
            820                 825                 830         


Gln Thr Leu Pro Gln Glu Tyr Gln Thr Gln Val Pro Thr Ile Pro Asn 
        835                 840                 845             


Gly His Asn Ser Ser Leu Pro Met Val Phe Gln Asp Leu Pro Asn Thr 
    850                 855                 860                 


Leu Asp Glu Ile Asp Ala Leu Leu Thr Glu Glu Arg Ser Arg Ala Ser 
865                 870                 875                 880 


Cys Phe Thr Gly Leu Asn Pro Thr Ile Val Gln Glu Tyr Thr Lys Arg 
                885                 890                 895     


Glu Glu Glu Ile Glu Gln Leu Thr Glu Glu Leu Lys Gly Lys Lys Val 
            900                 905                 910         


Glu Leu Asp Gln Tyr Arg Glu Asn Ile Ser Gln Val Lys Glu Arg Trp 
        915                 920                 925             


Leu Asn Pro Leu Lys Glu Leu Val Glu Lys Ile Asn Glu Lys Phe Ser 
    930                 935                 940                 


Asn Phe Phe Ser Ser Met Gln Cys Ala Gly Glu Val Asp Leu His Thr 
945                 950                 955                 960 


Glu Asn Glu Glu Asp Tyr Asp Lys Tyr Gly Ile Arg Ile Arg Val Lys 
                965                 970                 975     


Phe Arg Ser Ser Thr Gln Leu His Glu Leu Thr Pro His His Gln Ser 
            980                 985                 990         


Gly Gly Glu Arg Ser Val Ser Thr  Met Leu Tyr Leu Met  Ala Leu Gln 
        995                 1000                 1005             


Glu Leu  Asn Arg Cys Pro Phe  Arg Val Val Asp Glu  Ile Asn Gln 
    1010                 1015                 1020             


Gly Met  Asp Pro Ile Asn Glu  Arg Arg Val Phe Glu  Met Val Val 
    1025                 1030                 1035             


Asn Thr  Ala Cys Lys Glu Asn  Thr Ser Gln Tyr Phe  Phe Ile Thr 
    1040                 1045                 1050             


Pro Lys  Leu Leu Gln Asn Leu  Pro Tyr Ser Glu Lys  Met Thr Val 
    1055                 1060                 1065             


Leu Phe  Val Tyr Asn Gly Pro  His Met Leu Glu Pro  Asn Thr Trp 
    1070                 1075                 1080             


Asn Leu  Lys Ala Phe Gln Arg  Arg Arg Arg Arg Ile  Thr Phe Thr 
    1085                 1090                 1095             


Gln Pro  Ser 
    1100     


<210>  2727
<211>  434
<212>  PRT
<213>  homo sapiens

<400>  2727

Met Leu Pro Ala Arg Cys Ala Arg Leu Leu Thr Pro His Leu Leu Leu 
1               5                   10                  15      


Val Leu Val Gln Leu Ser Pro Ala Arg Gly His Arg Thr Thr Gly Pro 
            20                  25                  30          


Arg Phe Leu Ile Ser Asp Arg Asp Pro Gln Cys Asn Leu His Cys Ser 
        35                  40                  45              


Arg Thr Gln Pro Lys Pro Ile Cys Ala Ser Asp Gly Arg Ser Tyr Glu 
    50                  55                  60                  


Ser Met Cys Glu Tyr Gln Arg Ala Lys Cys Arg Asp Pro Thr Leu Gly 
65                  70                  75                  80  


Val Val His Arg Gly Arg Cys Lys Asp Ala Gly Gln Ser Lys Cys Arg 
                85                  90                  95      


Leu Glu Arg Ala Gln Ala Leu Glu Gln Ala Lys Lys Pro Gln Glu Ala 
            100                 105                 110         


Val Phe Val Pro Glu Cys Gly Glu Asp Gly Ser Phe Thr Gln Val Gln 
        115                 120                 125             


Cys His Thr Tyr Thr Gly Tyr Cys Trp Cys Val Thr Pro Asp Gly Lys 
    130                 135                 140                 


Pro Ile Ser Gly Ser Ser Val Gln Asn Lys Thr Pro Val Cys Ser Gly 
145                 150                 155                 160 


Ser Val Thr Asp Lys Pro Leu Ser Gln Gly Asn Ser Gly Arg Lys Asp 
                165                 170                 175     


Asp Gly Ser Lys Pro Thr Pro Thr Met Glu Thr Gln Pro Val Phe Asp 
            180                 185                 190         


Gly Asp Glu Ile Thr Ala Pro Thr Leu Trp Ile Lys His Leu Val Ile 
        195                 200                 205             


Lys Asp Ser Lys Leu Asn Asn Thr Asn Ile Arg Asn Ser Glu Lys Val 
    210                 215                 220                 


Tyr Ser Cys Asp Gln Glu Arg Gln Ser Ala Leu Glu Glu Ala Gln Gln 
225                 230                 235                 240 


Asn Pro Arg Glu Gly Ile Val Ile Pro Glu Cys Ala Pro Gly Gly Leu 
                245                 250                 255     


Tyr Lys Pro Val Gln Cys His Gln Ser Thr Gly Tyr Cys Trp Cys Val 
            260                 265                 270         


Leu Val Asp Thr Gly Arg Pro Leu Pro Gly Thr Ser Thr Arg Tyr Val 
        275                 280                 285             


Met Pro Ser Cys Glu Ser Asp Ala Arg Ala Lys Thr Thr Glu Ala Asp 
    290                 295                 300                 


Asp Pro Phe Lys Asp Arg Glu Leu Pro Gly Cys Pro Glu Gly Lys Lys 
305                 310                 315                 320 


Met Glu Phe Ile Thr Ser Leu Leu Asp Ala Leu Thr Thr Asp Met Val 
                325                 330                 335     


Gln Ala Ile Asn Ser Ala Ala Pro Thr Gly Gly Gly Arg Phe Ser Glu 
            340                 345                 350         


Pro Asp Pro Ser His Thr Leu Glu Glu Arg Val Val His Trp Tyr Phe 
        355                 360                 365             


Ser Gln Leu Asp Ser Asn Ser Ser Asn Asp Ile Asn Lys Arg Glu Met 
    370                 375                 380                 


Lys Pro Phe Lys Arg Tyr Val Lys Lys Lys Ala Lys Pro Lys Lys Cys 
385                 390                 395                 400 


Ala Arg Arg Phe Thr Asp Tyr Cys Asp Leu Asn Lys Asp Lys Val Ile 
                405                 410                 415     


Ser Leu Pro Glu Leu Lys Gly Cys Leu Gly Val Ser Lys Glu Gly Arg 
            420                 425                 430         


Leu Val 
        


<210>  2728
<211>  154
<212>  PRT
<213>  homo sapiens

<400>  2728

Met Ala Met Ile Ser Gly Leu Ser Gly Arg Lys Ser Ser Thr Gly Ser 
1               5                   10                  15      


Pro Thr Ser Pro Leu Asn Ala Glu Lys Leu Glu Ser Glu Glu Asp Val 
            20                  25                  30          


Ser Gln Ala Phe Leu Glu Ala Val Ala Glu Glu Lys Pro His Val Lys 
        35                  40                  45              


Pro Tyr Phe Ser Lys Thr Ile Arg Asp Leu Glu Val Val Glu Gly Ser 
    50                  55                  60                  


Ala Ala Arg Phe Asp Cys Lys Ile Glu Gly Tyr Pro Asp Pro Glu Val 
65                  70                  75                  80  


Val Trp Phe Lys Asp Asp Gln Ser Ile Arg Glu Ser Arg His Phe Gln 
                85                  90                  95      


Ile Asp Tyr Asp Glu Asp Gly Asn Cys Ser Leu Ile Ile Ser Asp Val 
            100                 105                 110         


Cys Gly Asp Asp Asp Ala Lys Tyr Thr Cys Lys Ala Val Asn Ser Leu 
        115                 120                 125             


Gly Glu Ala Thr Cys Thr Ala Glu Leu Ile Val Glu Thr Met Glu Glu 
    130                 135                 140                 


Gly Glu Gly Glu Gly Glu Glu Glu Glu Glu 
145                 150                 


<210>  2729
<211>  845
<212>  PRT
<213>  homo sapiens

<400>  2729

Met Leu Ser Gly Val Trp Phe Leu Ser Val Leu Thr Val Ala Gly Ile 
1               5                   10                  15      


Leu Gln Thr Glu Ser Arg Lys Thr Ala Lys Asp Ile Cys Lys Ile Arg 
            20                  25                  30          


Cys Leu Cys Glu Glu Lys Glu Asn Val Leu Asn Ile Asn Cys Glu Asn 
        35                  40                  45              


Lys Gly Phe Thr Thr Val Ser Leu Leu Gln Pro Pro Gln Tyr Arg Ile 
    50                  55                  60                  


Tyr Gln Leu Phe Leu Asn Gly Asn Leu Leu Thr Arg Leu Tyr Pro Asn 
65                  70                  75                  80  


Glu Phe Val Asn Tyr Ser Asn Ala Val Thr Leu His Leu Gly Asn Asn 
                85                  90                  95      


Gly Leu Gln Glu Ile Arg Thr Gly Ala Phe Ser Gly Leu Lys Thr Leu 
            100                 105                 110         


Lys Arg Leu His Leu Asn Asn Asn Lys Leu Glu Ile Leu Arg Glu Asp 
        115                 120                 125             


Thr Phe Leu Gly Leu Glu Ser Leu Glu Tyr Leu Gln Ala Asp Tyr Asn 
    130                 135                 140                 


Tyr Ile Ser Ala Ile Glu Ala Gly Ala Phe Ser Lys Leu Asn Lys Leu 
145                 150                 155                 160 


Lys Val Leu Ile Leu Asn Asp Asn Leu Leu Leu Ser Leu Pro Ser Asn 
                165                 170                 175     


Val Phe Arg Phe Val Leu Leu Thr His Leu Asp Leu Arg Gly Asn Arg 
            180                 185                 190         


Leu Lys Val Met Pro Phe Ala Gly Val Leu Glu His Ile Gly Gly Ile 
        195                 200                 205             


Met Glu Ile Gln Leu Glu Glu Asn Pro Trp Asn Cys Thr Cys Asp Leu 
    210                 215                 220                 


Leu Pro Leu Lys Ala Trp Leu Asp Thr Ile Thr Val Phe Val Gly Glu 
225                 230                 235                 240 


Ile Val Cys Glu Thr Pro Phe Arg Leu His Gly Lys Asp Val Thr Gln 
                245                 250                 255     


Leu Thr Arg Gln Asp Leu Cys Pro Arg Lys Ser Ala Ser Asp Ser Ser 
            260                 265                 270         


Gln Arg Gly Ser His Ala Asp Thr His Val Gln Arg Leu Ser Pro Thr 
        275                 280                 285             


Met Asn Pro Ala Leu Asn Pro Thr Arg Ala Pro Lys Ala Ser Arg Pro 
    290                 295                 300                 


Pro Lys Met Arg Asn Arg Pro Thr Pro Arg Val Thr Val Ser Lys Asp 
305                 310                 315                 320 


Arg Gln Ser Phe Gly Pro Ile Met Val Tyr Gln Thr Lys Ser Pro Val 
                325                 330                 335     


Pro Leu Thr Cys Pro Ser Ser Cys Val Cys Thr Ser Gln Ser Ser Asp 
            340                 345                 350         


Asn Gly Leu Asn Val Asn Cys Gln Glu Arg Lys Phe Thr Asn Ile Ser 
        355                 360                 365             


Asp Leu Gln Pro Lys Pro Thr Ser Pro Lys Lys Leu Tyr Leu Thr Gly 
    370                 375                 380                 


Asn Tyr Leu Gln Thr Val Tyr Lys Asn Asp Leu Leu Glu Tyr Ser Ser 
385                 390                 395                 400 


Leu Asp Leu Leu His Leu Gly Asn Asn Arg Ile Ala Val Ile Gln Glu 
                405                 410                 415     


Gly Ala Phe Thr Asn Leu Thr Ser Leu Arg Arg Leu Tyr Leu Asn Gly 
            420                 425                 430         


Asn Tyr Leu Glu Val Leu Tyr Pro Ser Met Phe Asp Gly Leu Gln Ser 
        435                 440                 445             


Leu Gln Tyr Leu Tyr Leu Glu Tyr Asn Val Ile Lys Glu Ile Lys Pro 
    450                 455                 460                 


Leu Thr Phe Asp Ala Leu Ile Asn Leu Gln Leu Leu Phe Leu Asn Asn 
465                 470                 475                 480 


Asn Leu Leu Arg Ser Leu Pro Asp Asn Ile Phe Gly Gly Thr Ala Leu 
                485                 490                 495     


Thr Arg Leu Asn Leu Arg Asn Asn His Phe Ser His Leu Pro Val Lys 
            500                 505                 510         


Gly Val Leu Asp Gln Leu Pro Ala Phe Ile Gln Ile Asp Leu Gln Glu 
        515                 520                 525             


Asn Pro Trp Asp Cys Thr Cys Asp Ile Met Gly Leu Lys Asp Trp Thr 
    530                 535                 540                 


Glu His Ala Asn Ser Pro Val Ile Ile Asn Glu Val Thr Cys Glu Ser 
545                 550                 555                 560 


Pro Ala Lys His Ala Gly Glu Ile Leu Lys Phe Leu Gly Arg Glu Ala 
                565                 570                 575     


Ile Cys Pro Asp Ser Pro Asn Leu Ser Asp Gly Thr Val Leu Ser Met 
            580                 585                 590         


Asn His Asn Thr Asp Thr Pro Arg Ser Leu Ser Val Ser Pro Ser Ser 
        595                 600                 605             


Tyr Pro Glu Leu His Thr Glu Val Pro Leu Ser Val Leu Ile Leu Gly 
    610                 615                 620                 


Leu Leu Val Val Phe Ile Leu Ser Val Cys Phe Gly Ala Gly Leu Phe 
625                 630                 635                 640 


Val Phe Val Leu Lys Arg Arg Lys Gly Val Pro Ser Val Pro Arg Asn 
                645                 650                 655     


Thr Asn Asn Leu Asp Val Ser Ser Phe Gln Leu Gln Tyr Gly Ser Tyr 
            660                 665                 670         


Asn Thr Glu Thr His Asp Lys Thr Asp Gly His Val Tyr Asn Tyr Ile 
        675                 680                 685             


Pro Pro Pro Val Gly Gln Met Cys Gln Asn Pro Ile Tyr Met Gln Lys 
    690                 695                 700                 


Glu Gly Asp Pro Val Ala Tyr Tyr Arg Asn Leu Gln Glu Phe Ser Tyr 
705                 710                 715                 720 


Ser Asn Leu Glu Glu Lys Lys Glu Glu Pro Ala Thr Pro Ala Tyr Thr 
                725                 730                 735     


Ile Ser Ala Thr Glu Leu Leu Glu Lys Gln Ala Thr Pro Arg Glu Pro 
            740                 745                 750         


Glu Leu Leu Tyr Gln Asn Ile Ala Glu Arg Val Lys Glu Leu Pro Ser 
        755                 760                 765             


Ala Gly Leu Val His Tyr Asn Phe Cys Thr Leu Pro Lys Arg Gln Phe 
    770                 775                 780                 


Ala Pro Ser Tyr Glu Ser Arg Arg Gln Asn Gln Asp Arg Ile Asn Lys 
785                 790                 795                 800 


Thr Val Leu Tyr Gly Thr Pro Arg Lys Cys Phe Val Gly Gln Ser Lys 
                805                 810                 815     


Pro Asn His Pro Leu Leu Gln Ala Lys Pro Gln Ser Glu Pro Asp Tyr 
            820                 825                 830         


Leu Glu Val Leu Glu Lys Gln Thr Ala Ile Ser Gln Leu 
        835                 840                 845 


<210>  2730
<211>  532
<212>  PRT
<213>  homo sapiens

<400>  2730

Met Leu Leu Asp Ala Gly Pro Gln Phe Pro Ala Ile Gly Val Gly Ser 
1               5                   10                  15      


Phe Ala Arg His His His His Ser Ala Ala Ala Ala Ala Ala Ala Ala 
            20                  25                  30          


Ala Glu Met Gln Asp Arg Glu Leu Ser Leu Ala Ala Ala Gln Asn Gly 
        35                  40                  45              


Phe Val Asp Ser Ala Ala Ala His Met Gly Ala Phe Lys Leu Asn Pro 
    50                  55                  60                  


Gly Ala His Glu Leu Ser Pro Gly Gln Ser Ser Ala Phe Thr Ser Gln 
65                  70                  75                  80  


Gly Pro Gly Ala Tyr Pro Gly Ser Ala Ala Ala Ala Ala Ala Ala Ala 
                85                  90                  95      


Ala Leu Gly Pro His Ala Ala His Val Gly Ser Tyr Ser Gly Pro Pro 
            100                 105                 110         


Phe Asn Ser Thr Arg Asp Phe Leu Phe Arg Ser Arg Gly Phe Gly Asp 
        115                 120                 125             


Ser Ala Pro Gly Gly Gly Gln His Gly Leu Phe Gly Pro Gly Ala Gly 
    130                 135                 140                 


Gly Leu His His Ala His Ser Asp Ala Gln Gly His Leu Leu Phe Pro 
145                 150                 155                 160 


Gly Leu Pro Glu Gln His Gly Pro His Gly Ser Gln Asn Val Leu Asn 
                165                 170                 175     


Gly Gln Met Arg Leu Gly Leu Pro Gly Glu Val Phe Gly Arg Ser Glu 
            180                 185                 190         


Gln Tyr Arg Gln Val Ala Ser Pro Arg Thr Asp Pro Tyr Ser Ala Ala 
        195                 200                 205             


Gln Leu His Asn Gln Tyr Gly Pro Met Asn Met Asn Met Gly Met Asn 
    210                 215                 220                 


Met Ala Ala Ala Ala Ala His His His His His His His His His Pro 
225                 230                 235                 240 


Gly Ala Phe Phe Arg Tyr Met Arg Gln Gln Cys Ile Lys Gln Glu Leu 
                245                 250                 255     


Ile Cys Lys Trp Ile Asp Pro Glu Gln Leu Ser Asn Pro Lys Lys Ser 
            260                 265                 270         


Cys Asn Lys Thr Phe Ser Thr Met His Glu Leu Val Thr His Val Ser 
        275                 280                 285             


Val Glu His Val Gly Gly Pro Glu Gln Ser Asn His Val Cys Phe Trp 
    290                 295                 300                 


Glu Glu Cys Pro Arg Glu Gly Lys Pro Phe Lys Ala Lys Tyr Lys Leu 
305                 310                 315                 320 


Val Asn His Ile Arg Val His Thr Gly Glu Lys Pro Phe Pro Cys Pro 
                325                 330                 335     


Phe Pro Gly Cys Gly Lys Val Phe Ala Arg Ser Glu Asn Leu Lys Ile 
            340                 345                 350         


His Lys Arg Thr His Thr Gly Glu Lys Pro Phe Gln Cys Glu Phe Glu 
        355                 360                 365             


Gly Cys Asp Arg Arg Phe Ala Asn Ser Ser Asp Arg Lys Lys His Met 
    370                 375                 380                 


His Val His Thr Ser Asp Lys Pro Tyr Leu Cys Lys Met Cys Asp Lys 
385                 390                 395                 400 


Ser Tyr Thr His Pro Ser Ser Leu Arg Lys His Met Lys Val His Glu 
                405                 410                 415     


Ser Ser Pro Gln Gly Ser Glu Ser Ser Pro Ala Ala Ser Ser Gly Tyr 
            420                 425                 430         


Glu Ser Ser Thr Pro Pro Gly Leu Val Ser Pro Ser Ala Glu Pro Gln 
        435                 440                 445             


Ser Ser Ser Asn Leu Ser Pro Ala Ala Ala Ala Ala Ala Ala Ala Ala 
    450                 455                 460                 


Ala Ala Ala Ala Ala Ala Val Ser Ala Val His Arg Gly Gly Gly Ser 
465                 470                 475                 480 


Gly Ser Gly Gly Ala Gly Gly Gly Ser Gly Gly Gly Ser Gly Ser Gly 
                485                 490                 495     


Gly Gly Gly Gly Gly Ala Gly Gly Gly Gly Gly Gly Ser Ser Gly Gly 
            500                 505                 510         


Gly Ser Gly Thr Ala Gly Gly His Ser Gly Leu Ser Ser Asn Phe Asn 
        515                 520                 525             


Glu Trp Tyr Val 
    530         


<210>  2731
<211>  464
<212>  PRT
<213>  homo sapiens

<400>  2731

Met Asp Tyr Asp Phe Lys Val Lys Leu Ser Ser Glu Arg Glu Arg Val 
1               5                   10                  15      


Glu Asp Leu Phe Glu Tyr Glu Gly Cys Lys Val Gly Arg Gly Thr Tyr 
            20                  25                  30          


Gly His Val Tyr Lys Ala Lys Arg Lys Asp Gly Lys Asp Asp Lys Asp 
        35                  40                  45              


Tyr Ala Leu Lys Gln Ile Glu Gly Thr Gly Ile Ser Met Ser Ala Cys 
    50                  55                  60                  


Arg Glu Ile Ala Leu Leu Arg Glu Leu Lys His Pro Asn Val Ile Ser 
65                  70                  75                  80  


Leu Gln Lys Val Phe Leu Ser His Ala Asp Arg Lys Val Trp Leu Leu 
                85                  90                  95      


Phe Asp Tyr Ala Glu His Asp Leu Trp His Ile Ile Lys Phe His Arg 
            100                 105                 110         


Ala Ser Lys Ala Asn Lys Lys Pro Val Gln Leu Pro Arg Gly Met Val 
        115                 120                 125             


Lys Ser Leu Leu Tyr Gln Ile Leu Asp Gly Ile His Tyr Leu His Ala 
    130                 135                 140                 


Asn Trp Val Leu His Arg Asp Leu Lys Pro Ala Asn Ile Leu Val Met 
145                 150                 155                 160 


Gly Glu Gly Pro Glu Arg Gly Arg Val Lys Ile Ala Asp Met Gly Phe 
                165                 170                 175     


Ala Arg Leu Phe Asn Ser Pro Leu Lys Pro Leu Ala Asp Leu Asp Pro 
            180                 185                 190         


Val Val Val Thr Phe Trp Tyr Arg Ala Pro Glu Leu Leu Leu Gly Ala 
        195                 200                 205             


Arg His Tyr Thr Lys Ala Ile Asp Ile Trp Ala Ile Gly Cys Ile Phe 
    210                 215                 220                 


Ala Glu Leu Leu Thr Ser Glu Pro Ile Phe His Cys Arg Gln Glu Asp 
225                 230                 235                 240 


Ile Lys Thr Ser Asn Pro Tyr His His Asp Gln Leu Asp Arg Ile Phe 
                245                 250                 255     


Asn Val Met Gly Phe Pro Ala Asp Lys Asp Trp Glu Asp Ile Lys Lys 
            260                 265                 270         


Met Pro Glu His Ser Thr Leu Met Lys Asp Phe Arg Arg Asn Thr Tyr 
        275                 280                 285             


Thr Asn Cys Ser Leu Ile Lys Tyr Met Glu Lys His Lys Val Lys Pro 
    290                 295                 300                 


Asp Ser Lys Ala Phe His Leu Leu Gln Lys Leu Leu Thr Met Asp Pro 
305                 310                 315                 320 


Ile Lys Arg Ile Thr Ser Glu Gln Ala Met Gln Asp Pro Tyr Phe Leu 
                325                 330                 335     


Glu Asp Pro Leu Pro Thr Ser Asp Val Phe Ala Gly Cys Gln Ile Pro 
            340                 345                 350         


Tyr Pro Lys Arg Glu Phe Leu Thr Glu Glu Glu Pro Asp Asp Lys Gly 
        355                 360                 365             


Asp Lys Lys Asn Gln Gln Gln Gln Gln Gly Asn Asn His Thr Asn Gly 
    370                 375                 380                 


Thr Gly His Pro Gly Asn Gln Asp Ser Ser His Thr Gln Gly Pro Pro 
385                 390                 395                 400 


Leu Lys Lys Val Arg Val Val Pro Pro Thr Thr Thr Ser Gly Gly Leu 
                405                 410                 415     


Ile Met Thr Ser Asp Tyr Gln Arg Ser Asn Pro His Ala Ala Tyr Pro 
            420                 425                 430         


Asn Pro Gly Pro Ser Thr Ser Gln Pro Gln Ser Ser Met Gly Tyr Ser 
        435                 440                 445             


Ala Thr Ser Gln Gln Pro Pro Gln Tyr Ser His Gln Thr His Arg Tyr 
    450                 455                 460                 


<210>  2732
<211>  706
<212>  PRT
<213>  homo sapiens

<400>  2732

Met Asn Pro Gln Gln Gln Arg Met Ala Ala Ile Gly Thr Asp Lys Glu 
1               5                   10                  15      


Leu Ser Asp Leu Leu Asp Phe Ser Ala Met Phe Ser Pro Pro Val Asn 
            20                  25                  30          


Ser Gly Lys Thr Arg Pro Thr Thr Leu Gly Ser Ser Gln Phe Ser Gly 
        35                  40                  45              


Ser Gly Ile Asp Glu Arg Gly Gly Thr Thr Ser Trp Gly Thr Ser Gly 
    50                  55                  60                  


Gln Pro Ser Pro Ser Tyr Asp Ser Ser Arg Gly Phe Thr Asp Ser Pro 
65                  70                  75                  80  


His Tyr Ser Asp His Leu Asn Asp Ser Arg Leu Gly Ala His Glu Gly 
                85                  90                  95      


Leu Ser Pro Thr Pro Phe Met Asn Ser Asn Leu Met Gly Lys Thr Ser 
            100                 105                 110         


Glu Arg Gly Ser Phe Ser Leu Tyr Ser Arg Asp Thr Gly Leu Pro Gly 
        115                 120                 125             


Cys Gln Ser Ser Leu Leu Arg Gln Asp Leu Gly Leu Gly Ser Pro Ala 
    130                 135                 140                 


Gln Leu Ser Ser Ser Gly Lys Pro Gly Thr Ala Tyr Tyr Ser Phe Ser 
145                 150                 155                 160 


Ala Thr Ser Ser Arg Arg Arg Pro Leu His Asp Ser Ala Ala Leu Asp 
                165                 170                 175     


Pro Leu Gln Ala Lys Lys Val Arg Lys Val Pro Pro Gly Leu Pro Ser 
            180                 185                 190         


Ser Val Tyr Ala Pro Ser Pro Asn Ser Asp Asp Phe Asn Arg Glu Ser 
        195                 200                 205             


Pro Ser Tyr Pro Ser Pro Lys Pro Pro Thr Ser Met Phe Ala Ser Thr 
    210                 215                 220                 


Phe Phe Met Gln Asp Gly Thr His Asn Ser Ser Asp Leu Trp Ser Ser 
225                 230                 235                 240 


Ser Asn Gly Met Ser Gln Pro Gly Phe Gly Gly Ile Leu Gly Thr Ser 
                245                 250                 255     


Thr Ser His Met Ser Gln Ser Ser Ser Tyr Gly Asn Leu His Ser His 
            260                 265                 270         


Asp Arg Leu Ser Tyr Pro Pro His Ser Val Ser Pro Thr Asp Ile Asn 
        275                 280                 285             


Thr Ser Leu Pro Pro Met Ser Ser Phe His Arg Gly Ser Thr Ser Ser 
    290                 295                 300                 


Ser Pro Tyr Val Ala Ala Ser His Thr Pro Pro Ile Asn Gly Ser Asp 
305                 310                 315                 320 


Ser Ile Leu Gly Thr Arg Gly Asn Ala Ala Gly Ser Ser Gln Thr Gly 
                325                 330                 335     


Asp Ala Leu Gly Lys Ala Leu Ala Ser Ile Tyr Ser Pro Asp His Thr 
            340                 345                 350         


Ser Ser Ser Phe Pro Ser Asn Pro Ser Thr Pro Val Gly Ser Pro Ser 
        355                 360                 365             


Pro Leu Thr Gly Thr Ser Gln Trp Pro Arg Pro Gly Gly Gln Ala Pro 
    370                 375                 380                 


Ser Ser Pro Ser Tyr Glu Asn Ser Leu His Ser Leu Lys Asn Arg Val 
385                 390                 395                 400 


Glu Gln Gln Leu His Glu His Leu Gln Asp Ala Met Ser Phe Leu Lys 
                405                 410                 415     


Asp Val Cys Glu Gln Ser Arg Met Glu Asp Arg Leu Asp Arg Leu Asp 
            420                 425                 430         


Asp Ala Ile His Val Leu Arg Asn His Ala Val Gly Pro Ser Thr Ser 
        435                 440                 445             


Leu Pro Ala Gly His Ser Asp Ile His Ser Leu Leu Gly Pro Ser His 
    450                 455                 460                 


Asn Ala Pro Ile Gly Ser Leu Asn Ser Asn Tyr Gly Gly Ser Ser Leu 
465                 470                 475                 480 


Val Ala Ser Ser Arg Ser Ala Ser Met Val Gly Thr His Arg Glu Asp 
                485                 490                 495     


Ser Val Ser Leu Asn Gly Asn His Ser Val Leu Ser Ser Thr Val Thr 
            500                 505                 510         


Thr Ser Ser Thr Asp Leu Asn His Lys Thr Gln Glu Asn Tyr Arg Gly 
        515                 520                 525             


Gly Leu Gln Ser Gln Ser Gly Thr Val Val Thr Thr Glu Ile Lys Thr 
    530                 535                 540                 


Glu Asn Lys Glu Lys Asp Glu Asn Leu His Glu Pro Pro Ser Ser Asp 
545                 550                 555                 560 


Asp Met Lys Ser Asp Asp Glu Ser Ser Gln Lys Asp Ile Lys Val Ser 
                565                 570                 575     


Ser Arg Gly Arg Thr Ser Ser Thr Asn Glu Asp Glu Asp Leu Asn Pro 
            580                 585                 590         


Glu Gln Lys Ile Glu Arg Glu Lys Glu Arg Arg Met Ala Asn Asn Ala 
        595                 600                 605             


Arg Glu Arg Leu Arg Val Arg Asp Ile Asn Glu Ala Phe Lys Glu Leu 
    610                 615                 620                 


Gly Arg Met Cys Gln Leu His Leu Lys Ser Glu Lys Pro Gln Thr Lys 
625                 630                 635                 640 


Leu Leu Ile Leu His Gln Ala Val Ala Val Ile Leu Ser Leu Glu Gln 
                645                 650                 655     


Gln Val Arg Glu Arg Asn Leu Asn Pro Lys Ala Ala Cys Leu Lys Arg 
            660                 665                 670         


Arg Glu Glu Glu Lys Val Ser Ala Val Ser Ala Glu Pro Pro Thr Thr 
        675                 680                 685             


Leu Pro Gly Thr His Pro Gly Leu Ser Glu Thr Thr Asn Pro Met Gly 
    690                 695                 700                 


His Met 
705     


<210>  2733
<211>  682
<212>  PRT
<213>  homo sapiens

<400>  2733

Met Asn Pro Gln Gln Gln Arg Met Ala Ala Ile Gly Thr Asp Lys Glu 
1               5                   10                  15      


Leu Ser Asp Leu Leu Asp Phe Ser Ala Met Phe Ser Pro Pro Val Asn 
            20                  25                  30          


Ser Gly Lys Thr Arg Pro Thr Thr Leu Gly Ser Ser Gln Phe Ser Gly 
        35                  40                  45              


Ser Gly Ile Asp Glu Arg Gly Gly Thr Thr Ser Trp Gly Thr Ser Gly 
    50                  55                  60                  


Gln Pro Ser Pro Ser Tyr Asp Ser Ser Arg Gly Phe Thr Asp Ser Pro 
65                  70                  75                  80  


His Tyr Ser Asp His Leu Asn Asp Ser Arg Leu Gly Ala His Glu Gly 
                85                  90                  95      


Leu Ser Pro Thr Pro Phe Met Asn Ser Asn Leu Met Gly Lys Thr Ser 
            100                 105                 110         


Glu Arg Gly Ser Phe Ser Leu Tyr Ser Arg Asp Thr Gly Leu Pro Gly 
        115                 120                 125             


Cys Gln Ser Ser Leu Leu Arg Gln Asp Leu Gly Leu Gly Ser Pro Ala 
    130                 135                 140                 


Gln Leu Ser Ser Ser Gly Lys Pro Gly Thr Ala Tyr Tyr Ser Phe Ser 
145                 150                 155                 160 


Ala Thr Ser Ser Arg Arg Arg Pro Leu His Asp Ser Ala Ala Leu Asp 
                165                 170                 175     


Pro Leu Gln Ala Lys Lys Val Arg Lys Val Pro Pro Gly Leu Pro Ser 
            180                 185                 190         


Ser Val Tyr Ala Pro Ser Pro Asn Ser Asp Asp Phe Asn Arg Glu Ser 
        195                 200                 205             


Pro Ser Tyr Pro Ser Pro Lys Pro Pro Thr Ser Met Phe Ala Ser Thr 
    210                 215                 220                 


Phe Phe Met Gln Asp Gly Thr His Asn Ser Ser Asp Leu Trp Ser Ser 
225                 230                 235                 240 


Ser Asn Gly Met Ser Gln Pro Gly Phe Gly Gly Ile Leu Gly Thr Ser 
                245                 250                 255     


Thr Ser His Met Ser Gln Ser Ser Ser Tyr Gly Asn Leu His Ser His 
            260                 265                 270         


Asp Arg Leu Ser Tyr Pro Pro His Ser Val Ser Pro Thr Asp Ile Asn 
        275                 280                 285             


Thr Ser Leu Pro Pro Met Ser Ser Phe His Arg Gly Ser Thr Ser Ser 
    290                 295                 300                 


Ser Pro Tyr Val Ala Ala Ser His Thr Pro Pro Ile Asn Gly Ser Asp 
305                 310                 315                 320 


Ser Ile Leu Gly Thr Arg Gly Asn Ala Ala Gly Ser Ser Gln Thr Gly 
                325                 330                 335     


Asp Ala Leu Gly Lys Ala Leu Ala Ser Ile Tyr Ser Pro Asp His Thr 
            340                 345                 350         


Ser Ser Ser Phe Pro Ser Asn Pro Ser Thr Pro Val Gly Ser Pro Ser 
        355                 360                 365             


Pro Leu Thr Gly Thr Ser Gln Trp Pro Arg Pro Gly Gly Gln Ala Pro 
    370                 375                 380                 


Ser Ser Pro Ser Tyr Glu Asn Ser Leu His Ser Leu Gln Ser Arg Met 
385                 390                 395                 400 


Glu Asp Arg Leu Asp Arg Leu Asp Asp Ala Ile His Val Leu Arg Asn 
                405                 410                 415     


His Ala Val Gly Pro Ser Thr Ser Leu Pro Ala Gly His Ser Asp Ile 
            420                 425                 430         


His Ser Leu Leu Gly Pro Ser His Asn Ala Pro Ile Gly Ser Leu Asn 
        435                 440                 445             


Ser Asn Tyr Gly Gly Ser Ser Leu Val Ala Ser Ser Arg Ser Ala Ser 
    450                 455                 460                 


Met Val Gly Thr His Arg Glu Asp Ser Val Ser Leu Asn Gly Asn His 
465                 470                 475                 480 


Ser Val Leu Ser Ser Thr Val Thr Thr Ser Ser Thr Asp Leu Asn His 
                485                 490                 495     


Lys Thr Gln Glu Asn Tyr Arg Gly Gly Leu Gln Ser Gln Ser Gly Thr 
            500                 505                 510         


Val Val Thr Thr Glu Ile Lys Thr Glu Asn Lys Glu Lys Asp Glu Asn 
        515                 520                 525             


Leu His Glu Pro Pro Ser Ser Asp Asp Met Lys Ser Asp Asp Glu Ser 
    530                 535                 540                 


Ser Gln Lys Asp Ile Lys Val Ser Ser Arg Gly Arg Thr Ser Ser Thr 
545                 550                 555                 560 


Asn Glu Asp Glu Asp Leu Asn Pro Glu Gln Lys Ile Glu Arg Glu Lys 
                565                 570                 575     


Glu Arg Arg Met Ala Asn Asn Ala Arg Glu Arg Leu Arg Val Arg Asp 
            580                 585                 590         


Ile Asn Glu Ala Phe Lys Glu Leu Gly Arg Met Cys Gln Leu His Leu 
        595                 600                 605             


Lys Ser Glu Lys Pro Gln Thr Lys Leu Leu Ile Leu His Gln Ala Val 
    610                 615                 620                 


Ala Val Ile Leu Ser Leu Glu Gln Gln Val Arg Glu Arg Asn Leu Asn 
625                 630                 635                 640 


Pro Lys Ala Ala Cys Leu Lys Arg Arg Glu Glu Glu Lys Val Ser Ala 
                645                 650                 655     


Val Ser Ala Glu Pro Pro Thr Thr Leu Pro Gly Thr His Pro Gly Leu 
            660                 665                 670         


Ser Glu Thr Thr Asn Pro Met Gly His Met 
        675                 680         


<210>  2734
<211>  414
<212>  PRT
<213>  homo sapiens

<400>  2734

Met Ala Ser Val Val Leu Pro Ser Gly Ser Gln Cys Ala Ala Ala Ala 
1               5                   10                  15      


Ala Ala Ala Ala Pro Pro Gly Leu Arg Leu Arg Leu Leu Leu Leu Leu 
            20                  25                  30          


Phe Ser Ala Ala Ala Leu Ile Pro Thr Gly Asp Gly Gln Asn Leu Phe 
        35                  40                  45              


Thr Lys Asp Val Thr Val Ile Glu Gly Glu Val Ala Thr Ile Ser Cys 
    50                  55                  60                  


Gln Val Asn Lys Ser Asp Asp Ser Val Ile Gln Leu Leu Asn Pro Asn 
65                  70                  75                  80  


Arg Gln Thr Ile Tyr Phe Arg Asp Phe Arg Pro Leu Lys Asp Ser Arg 
                85                  90                  95      


Phe Gln Leu Leu Asn Phe Ser Ser Ser Glu Leu Lys Val Ser Leu Thr 
            100                 105                 110         


Asn Val Ser Ile Ser Asp Glu Gly Arg Tyr Phe Cys Gln Leu Tyr Thr 
        115                 120                 125             


Asp Pro Pro Gln Glu Ser Tyr Thr Thr Ile Thr Val Leu Val Pro Pro 
    130                 135                 140                 


Arg Asn Leu Met Ile Asp Ile Gln Lys Asp Thr Ala Val Glu Gly Glu 
145                 150                 155                 160 


Glu Ile Glu Val Asn Cys Thr Ala Met Ala Ser Lys Pro Ala Thr Thr 
                165                 170                 175     


Ile Arg Trp Phe Lys Gly Asn Thr Glu Leu Lys Gly Lys Ser Glu Val 
            180                 185                 190         


Glu Glu Trp Ser Asp Met Tyr Thr Val Thr Ser Gln Leu Met Leu Lys 
        195                 200                 205             


Val His Lys Glu Asp Asp Gly Val Pro Val Ile Cys Gln Val Glu His 
    210                 215                 220                 


Pro Ala Val Thr Gly Asn Leu Gln Thr Gln Arg Tyr Leu Glu Val Gln 
225                 230                 235                 240 


Tyr Lys Pro Gln Val His Ile Gln Met Thr Tyr Pro Leu Gln Gly Leu 
                245                 250                 255     


Thr Arg Glu Gly Asp Ala Leu Glu Leu Thr Cys Glu Ala Ile Gly Lys 
            260                 265                 270         


Pro Gln Pro Val Met Val Thr Trp Val Arg Val Asp Asp Glu Met Pro 
        275                 280                 285             


Gln His Ala Val Leu Ser Gly Pro Asn Leu Phe Ile Asn Asn Leu Asn 
    290                 295                 300                 


Lys Thr Asp Asn Gly Thr Tyr Arg Cys Glu Ala Ser Asn Ile Val Gly 
305                 310                 315                 320 


Lys Ala His Ser Asp Tyr Met Leu Tyr Val Tyr Asp Ser Arg Ala Gly 
                325                 330                 335     


Glu Glu Gly Ser Ile Arg Ala Val Asp His Ala Val Ile Gly Gly Val 
            340                 345                 350         


Val Ala Val Val Val Phe Ala Met Leu Cys Leu Leu Ile Ile Leu Gly 
        355                 360                 365             


Arg Tyr Phe Ala Arg His Lys Gly Thr Tyr Phe Thr His Glu Ala Lys 
    370                 375                 380                 


Gly Ala Asp Asp Ala Ala Asp Ala Asp Thr Ala Ile Ile Asn Ala Glu 
385                 390                 395                 400 


Gly Gly Gln Asn Asn Ser Glu Glu Lys Lys Glu Tyr Phe Ile 
                405                 410                 


<210>  2735
<211>  208
<212>  PRT
<213>  homo sapiens

<400>  2735

Met Gly Ser Cys Ser Gly Arg Cys Ala Leu Val Val Leu Cys Ala Phe 
1               5                   10                  15      


Gln Leu Val Ala Ala Leu Glu Arg Gln Val Phe Asp Phe Leu Gly Tyr 
            20                  25                  30          


Gln Trp Ala Pro Ile Leu Ala Asn Phe Val His Ile Ile Ile Val Ile 
        35                  40                  45              


Leu Gly Leu Phe Gly Thr Ile Gln Tyr Arg Leu Arg Tyr Val Met Val 
    50                  55                  60                  


Tyr Thr Leu Trp Ala Ala Val Trp Val Thr Trp Asn Val Phe Ile Ile 
65                  70                  75                  80  


Cys Phe Tyr Leu Glu Val Gly Gly Leu Leu Lys Asp Ser Glu Leu Leu 
                85                  90                  95      


Thr Phe Ser Leu Ser Arg His Arg Ser Trp Trp Arg Glu Arg Trp Pro 
            100                 105                 110         


Gly Cys Leu His Glu Glu Val Pro Ala Val Gly Leu Gly Ala Pro His 
        115                 120                 125             


Gly Gln Ala Leu Val Ser Gly Ala Gly Cys Ala Leu Glu Pro Ser Tyr 
    130                 135                 140                 


Val Glu Ala Leu His Ser Cys Leu Gln Ile Leu Ile Ala Leu Leu Gly 
145                 150                 155                 160 


Phe Val Cys Gly Cys Gln Val Val Ser Val Phe Thr Glu Glu Glu Asp 
                165                 170                 175     


Ser Phe Asp Phe Ile Gly Gly Phe Asp Pro Phe Pro Leu Tyr His Val 
            180                 185                 190         


Asn Glu Lys Pro Ser Ser Leu Leu Ser Lys Gln Val Tyr Leu Pro Ala 
        195                 200                 205             


<210>  2736
<211>  787
<212>  PRT
<213>  homo sapiens

<400>  2736

Met Ala Val Trp Ile Gln Ala Gln Gln Leu Gln Gly Glu Ala Leu His 
1               5                   10                  15      


Gln Met Gln Ala Leu Tyr Gly Gln His Phe Pro Ile Glu Val Arg His 
            20                  25                  30          


Tyr Leu Ser Gln Trp Ile Glu Ser Gln Ala Trp Asp Ser Val Asp Leu 
        35                  40                  45              


Asp Asn Pro Gln Glu Asn Ile Lys Ala Thr Gln Leu Leu Glu Gly Leu 
    50                  55                  60                  


Val Gln Glu Leu Gln Lys Lys Ala Glu His Gln Val Gly Glu Asp Gly 
65                  70                  75                  80  


Phe Leu Leu Lys Ile Lys Leu Gly His Tyr Ala Thr Gln Leu Gln Asn 
                85                  90                  95      


Thr Tyr Asp Arg Cys Pro Met Glu Leu Val Arg Cys Ile Arg His Ile 
            100                 105                 110         


Leu Tyr Asn Glu Gln Arg Leu Val Arg Glu Ala Asn Asn Gly Ser Ser 
        115                 120                 125             


Pro Ala Gly Ser Leu Ala Asp Ala Met Ser Gln Lys His Leu Gln Ile 
    130                 135                 140                 


Asn Gln Thr Phe Glu Glu Leu Arg Leu Val Thr Gln Asp Thr Glu Asn 
145                 150                 155                 160 


Glu Leu Lys Lys Leu Gln Gln Thr Gln Glu Tyr Phe Ile Ile Gln Tyr 
                165                 170                 175     


Gln Glu Ser Leu Arg Ile Gln Ala Gln Phe Gly Pro Leu Ala Gln Leu 
            180                 185                 190         


Ser Pro Gln Glu Arg Leu Ser Arg Glu Thr Ala Leu Gln Gln Lys Gln 
        195                 200                 205             


Val Ser Leu Glu Ala Trp Leu Gln Arg Glu Ala Gln Thr Leu Gln Gln 
    210                 215                 220                 


Tyr Arg Val Glu Leu Ala Glu Lys His Gln Lys Thr Leu Gln Leu Leu 
225                 230                 235                 240 


Arg Lys Gln Gln Thr Ile Ile Leu Asp Asp Glu Leu Ile Gln Trp Lys 
                245                 250                 255     


Arg Arg Gln Gln Leu Ala Gly Asn Gly Gly Pro Pro Glu Gly Ser Leu 
            260                 265                 270         


Asp Val Leu Gln Ser Trp Cys Glu Lys Leu Ala Glu Ile Ile Trp Gln 
        275                 280                 285             


Asn Arg Gln Gln Ile Arg Arg Ala Glu His Leu Cys Gln Gln Leu Pro 
    290                 295                 300                 


Ile Pro Gly Pro Val Glu Glu Met Leu Ala Glu Val Asn Ala Thr Ile 
305                 310                 315                 320 


Thr Asp Ile Ile Ser Ala Leu Val Thr Ser Thr Phe Ile Ile Glu Lys 
                325                 330                 335     


Gln Pro Pro Gln Val Leu Lys Thr Gln Thr Lys Phe Ala Ala Thr Val 
            340                 345                 350         


Arg Leu Leu Val Gly Gly Lys Leu Asn Val His Met Asn Pro Pro Gln 
        355                 360                 365             


Val Lys Ala Thr Ile Ile Ser Glu Gln Gln Ala Lys Ser Leu Leu Lys 
    370                 375                 380                 


Asn Glu Asn Thr Arg Asn Asp Tyr Ser Gly Glu Ile Leu Asn Asn Cys 
385                 390                 395                 400 


Cys Val Met Glu Tyr His Gln Ala Thr Gly Thr Leu Ser Ala His Phe 
                405                 410                 415     


Arg Asn Met Ser Leu Lys Arg Ile Lys Arg Ser Asp Arg Arg Gly Ala 
            420                 425                 430         


Glu Ser Val Thr Glu Glu Lys Phe Thr Ile Leu Phe Glu Ser Gln Phe 
        435                 440                 445             


Ser Val Gly Gly Asn Glu Leu Val Phe Gln Val Lys Thr Leu Ser Leu 
    450                 455                 460                 


Pro Val Val Val Ile Val His Gly Ser Gln Asp Asn Asn Ala Thr Ala 
465                 470                 475                 480 


Thr Val Leu Trp Asp Asn Ala Phe Ala Glu Pro Gly Arg Val Pro Phe 
                485                 490                 495     


Ala Val Pro Asp Lys Val Leu Trp Pro Gln Leu Cys Glu Ala Leu Asn 
            500                 505                 510         


Met Lys Phe Lys Ala Glu Val Gln Ser Asn Arg Gly Leu Thr Lys Glu 
        515                 520                 525             


Asn Leu Val Phe Leu Ala Gln Lys Leu Phe Asn Asn Ser Ser Ser His 
    530                 535                 540                 


Leu Glu Asp Tyr Ser Gly Leu Ser Val Ser Trp Ser Gln Phe Asn Arg 
545                 550                 555                 560 


Glu Asn Leu Pro Gly Arg Asn Tyr Thr Phe Trp Gln Trp Phe Asp Gly 
                565                 570                 575     


Val Met Glu Val Leu Lys Lys His Leu Lys Pro His Trp Asn Asp Gly 
            580                 585                 590         


Ala Ile Leu Gly Phe Val Asn Lys Gln Gln Ala His Asp Leu Leu Ile 
        595                 600                 605             


Asn Lys Pro Asp Gly Thr Phe Leu Leu Arg Phe Ser Asp Ser Glu Ile 
    610                 615                 620                 


Gly Gly Ile Thr Ile Ala Trp Lys Phe Asp Ser Gln Glu Arg Met Phe 
625                 630                 635                 640 


Trp Asn Leu Met Pro Phe Thr Thr Arg Asp Phe Ser Ile Arg Ser Leu 
                645                 650                 655     


Ala Asp Arg Leu Gly Asp Leu Asn Tyr Leu Ile Tyr Val Phe Pro Asp 
            660                 665                 670         


Arg Pro Lys Asp Glu Val Tyr Ser Lys Tyr Tyr Thr Pro Val Pro Cys 
        675                 680                 685             


Glu Ser Ala Thr Ala Lys Ala Val Asp Gly Tyr Val Lys Pro Gln Ile 
    690                 695                 700                 


Lys Gln Val Val Pro Glu Phe Val Asn Ala Ser Ala Asp Ala Gly Gly 
705                 710                 715                 720 


Gly Ser Ala Thr Tyr Met Asp Gln Ala Pro Ser Pro Ala Val Cys Pro 
                725                 730                 735     


Gln Ala His Tyr Asn Met Tyr Pro Gln Asn Pro Asp Ser Val Leu Asp 
            740                 745                 750         


Thr Asp Gly Asp Phe Asp Leu Glu Asp Thr Met Asp Val Ala Arg Arg 
        755                 760                 765             


Val Glu Glu Leu Leu Gly Arg Pro Met Asp Ser Gln Trp Ile Pro His 
    770                 775                 780                 


Ala Gln Ser 
785         


<210>  2737
<211>  479
<212>  PRT
<213>  homo sapiens

<400>  2737

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15      


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30          


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45              


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60                  


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80  


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95      


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
            100                 105                 110         


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
        115                 120                 125             


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
    130                 135                 140                 


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
145                 150                 155                 160 


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
                165                 170                 175     


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
            180                 185                 190         


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
        195                 200                 205             


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
    210                 215                 220                 


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
225                 230                 235                 240 


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
                245                 250                 255     


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
            260                 265                 270         


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
        275                 280                 285             


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
    290                 295                 300                 


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
305                 310                 315                 320 


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
                325                 330                 335     


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
            340                 345                 350         


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
        355                 360                 365             


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
    370                 375                 380                 


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
385                 390                 395                 400 


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
                405                 410                 415     


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
            420                 425                 430         


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
        435                 440                 445             


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
    450                 455                 460                 


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Val 
465                 470                 475                 


<210>  2738
<211>  879
<212>  PRT
<213>  homo sapiens

<400>  2738

Met Lys Met Leu Thr Arg Leu Gln Val Leu Thr Leu Ala Leu Phe Ser 
1               5                   10                  15      


Lys Gly Phe Leu Leu Ser Leu Gly Asp His Asn Phe Leu Arg Arg Glu 
            20                  25                  30          


Ile Lys Ile Glu Gly Asp Leu Val Leu Gly Gly Leu Phe Pro Ile Asn 
        35                  40                  45              


Glu Lys Gly Thr Gly Thr Glu Glu Cys Gly Arg Ile Asn Glu Asp Arg 
    50                  55                  60                  


Gly Ile Gln Arg Leu Glu Ala Met Leu Phe Ala Ile Asp Glu Ile Asn 
65                  70                  75                  80  


Lys Asp Asp Tyr Leu Leu Pro Gly Val Lys Leu Gly Val His Ile Leu 
                85                  90                  95      


Asp Thr Cys Ser Arg Asp Thr Tyr Ala Leu Glu Gln Ser Leu Glu Phe 
            100                 105                 110         


Val Arg Ala Ser Leu Thr Lys Val Asp Glu Ala Glu Tyr Met Cys Pro 
        115                 120                 125             


Asp Gly Ser Tyr Ala Ile Gln Glu Asn Ile Pro Leu Leu Ile Ala Gly 
    130                 135                 140                 


Val Ile Gly Gly Ser Tyr Ser Ser Val Ser Ile Gln Val Ala Asn Leu 
145                 150                 155                 160 


Leu Arg Leu Phe Gln Ile Pro Gln Ile Ser Tyr Ala Ser Thr Ser Ala 
                165                 170                 175     


Lys Leu Ser Asp Lys Ser Arg Tyr Asp Tyr Phe Ala Arg Thr Val Pro 
            180                 185                 190         


Pro Asp Phe Tyr Gln Ala Lys Ala Met Ala Glu Ile Leu Arg Phe Phe 
        195                 200                 205             


Asn Trp Thr Tyr Val Ser Thr Val Ala Ser Glu Gly Asp Tyr Gly Glu 
    210                 215                 220                 


Thr Gly Ile Glu Ala Phe Glu Gln Glu Ala Arg Leu Arg Asn Ile Cys 
225                 230                 235                 240 


Ile Ala Thr Ala Glu Lys Val Gly Arg Ser Asn Ile Arg Lys Ser Tyr 
                245                 250                 255     


Asp Ser Val Ile Arg Glu Leu Leu Gln Lys Pro Asn Ala Arg Val Val 
            260                 265                 270         


Val Leu Phe Met Arg Ser Asp Asp Ser Arg Glu Leu Ile Ala Ala Ala 
        275                 280                 285             


Ser Arg Ala Asn Ala Ser Phe Thr Trp Val Ala Ser Asp Gly Trp Gly 
    290                 295                 300                 


Ala Gln Glu Ser Ile Ile Lys Gly Ser Glu His Val Ala Tyr Gly Ala 
305                 310                 315                 320 


Ile Thr Leu Glu Leu Ala Ser Gln Pro Val Arg Gln Phe Asp Arg Tyr 
                325                 330                 335     


Phe Gln Ser Leu Asn Pro Tyr Asn Asn His Arg Asn Pro Trp Phe Arg 
            340                 345                 350         


Asp Phe Trp Glu Gln Lys Phe Gln Cys Ser Leu Gln Asn Lys Arg Asn 
        355                 360                 365             


His Arg Arg Val Cys Asp Lys His Leu Ala Ile Asp Ser Ser Asn Tyr 
    370                 375                 380                 


Glu Gln Glu Ser Lys Ile Met Phe Val Val Asn Ala Val Tyr Ala Met 
385                 390                 395                 400 


Ala His Ala Leu His Lys Met Gln Arg Thr Leu Cys Pro Asn Thr Thr 
                405                 410                 415     


Lys Leu Cys Asp Ala Met Lys Ile Leu Asp Gly Lys Lys Leu Tyr Lys 
            420                 425                 430         


Asp Tyr Leu Leu Lys Ile Asn Phe Thr Ala Pro Phe Asn Pro Asn Lys 
        435                 440                 445             


Asp Ala Asp Ser Ile Val Lys Phe Asp Thr Phe Gly Asp Gly Met Gly 
    450                 455                 460                 


Arg Tyr Asn Val Phe Asn Phe Gln Asn Val Gly Gly Lys Tyr Ser Tyr 
465                 470                 475                 480 


Leu Lys Val Gly His Trp Ala Glu Thr Leu Ser Leu Asp Val Asn Ser 
                485                 490                 495     


Ile His Trp Ser Arg Asn Ser Val Pro Thr Ser Gln Cys Ser Asp Pro 
            500                 505                 510         


Cys Ala Pro Asn Glu Met Lys Asn Met Gln Pro Gly Asp Val Cys Cys 
        515                 520                 525             


Trp Ile Cys Ile Pro Cys Glu Pro Tyr Glu Tyr Leu Ala Asp Glu Phe 
    530                 535                 540                 


Thr Cys Met Asp Cys Gly Ser Gly Gln Trp Pro Thr Ala Asp Leu Thr 
545                 550                 555                 560 


Gly Cys Tyr Asp Leu Pro Glu Asp Tyr Ile Arg Trp Glu Asp Ala Trp 
                565                 570                 575     


Ala Ile Gly Pro Val Thr Ile Ala Cys Leu Gly Phe Met Cys Thr Cys 
            580                 585                 590         


Met Val Val Thr Val Phe Ile Lys His Asn Asn Thr Pro Leu Val Lys 
        595                 600                 605             


Ala Ser Gly Arg Glu Leu Cys Tyr Ile Leu Leu Phe Gly Val Gly Leu 
    610                 615                 620                 


Ser Tyr Cys Met Thr Phe Phe Phe Ile Ala Lys Pro Ser Pro Val Ile 
625                 630                 635                 640 


Cys Ala Leu Arg Arg Leu Gly Leu Gly Ser Ser Phe Ala Ile Cys Tyr 
                645                 650                 655     


Ser Ala Leu Leu Thr Lys Thr Asn Cys Ile Ala Arg Ile Phe Asp Gly 
            660                 665                 670         


Val Lys Asn Gly Ala Gln Arg Pro Lys Phe Ile Ser Pro Ser Ser Gln 
        675                 680                 685             


Val Phe Ile Cys Leu Gly Leu Ile Leu Val Gln Ile Val Met Val Ser 
    690                 695                 700                 


Val Trp Leu Ile Leu Glu Ala Pro Gly Thr Arg Arg Tyr Thr Leu Ala 
705                 710                 715                 720 


Glu Lys Arg Glu Thr Val Ile Leu Lys Cys Asn Val Lys Asp Ser Ser 
                725                 730                 735     


Met Leu Ile Ser Leu Thr Tyr Asp Val Ile Leu Val Ile Leu Cys Thr 
            740                 745                 750         


Val Tyr Ala Phe Lys Thr Arg Lys Cys Pro Glu Asn Phe Asn Glu Ala 
        755                 760                 765             


Lys Phe Ile Gly Phe Thr Met Tyr Thr Thr Cys Ile Ile Trp Leu Ala 
    770                 775                 780                 


Phe Leu Pro Ile Phe Tyr Val Thr Ser Ser Asp Tyr Arg Val Gln Thr 
785                 790                 795                 800 


Thr Thr Met Cys Ile Ser Val Ser Leu Ser Gly Phe Val Val Leu Gly 
                805                 810                 815     


Cys Leu Phe Ala Pro Lys Val His Ile Ile Leu Phe Gln Pro Gln Lys 
            820                 825                 830         


Asn Val Val Thr His Arg Leu His Leu Asn Arg Phe Ser Val Ser Gly 
        835                 840                 845             


Thr Gly Thr Thr Tyr Ser Gln Ser Ser Ala Ser Thr Tyr Val Pro Thr 
    850                 855                 860                 


Val Cys Asn Gly Arg Glu Val Leu Asp Ser Thr Thr Ser Ser Leu 
865                 870                 875                 


<210>  2739
<211>  581
<212>  PRT
<213>  homo sapiens

<400>  2739

Met Gln Arg Pro Gly Pro Arg Leu Trp Leu Val Leu Gln Val Met Gly 
1               5                   10                  15      


Ser Cys Ala Ala Ile Ser Ser Met Asp Met Glu Arg Pro Gly Asp Gly 
            20                  25                  30          


Lys Cys Gln Pro Ile Glu Ile Pro Met Cys Lys Asp Ile Gly Tyr Asn 
        35                  40                  45              


Met Thr Arg Met Pro Asn Leu Met Gly His Glu Asn Gln Arg Glu Ala 
    50                  55                  60                  


Ala Ile Gln Leu His Glu Phe Ala Pro Leu Val Glu Tyr Gly Cys His 
65                  70                  75                  80  


Gly His Leu Arg Phe Phe Leu Cys Ser Leu Tyr Ala Pro Met Cys Thr 
                85                  90                  95      


Glu Gln Val Ser Thr Pro Ile Pro Ala Cys Arg Val Met Cys Glu Gln 
            100                 105                 110         


Ala Arg Leu Lys Cys Ser Pro Ile Met Glu Gln Phe Asn Phe Lys Trp 
        115                 120                 125             


Pro Asp Ser Leu Asp Cys Arg Lys Leu Pro Asn Lys Asn Asp Pro Asn 
    130                 135                 140                 


Tyr Leu Cys Met Glu Ala Pro Asn Asn Gly Ser Asp Glu Pro Thr Arg 
145                 150                 155                 160 


Gly Ser Gly Leu Phe Pro Pro Leu Phe Arg Pro Gln Arg Pro His Ser 
                165                 170                 175     


Ala Gln Glu His Pro Leu Lys Asp Gly Gly Pro Gly Arg Gly Gly Cys 
            180                 185                 190         


Asp Asn Pro Gly Lys Phe His His Val Glu Lys Ser Ala Ser Cys Ala 
        195                 200                 205             


Pro Leu Cys Thr Pro Gly Val Asp Val Tyr Trp Ser Arg Glu Asp Lys 
    210                 215                 220                 


Arg Phe Ala Val Val Trp Leu Ala Ile Trp Ala Val Leu Cys Phe Phe 
225                 230                 235                 240 


Ser Ser Ala Phe Thr Val Leu Thr Phe Leu Ile Asp Pro Ala Arg Phe 
                245                 250                 255     


Arg Tyr Pro Glu Arg Pro Ile Ile Phe Leu Ser Met Cys Tyr Cys Val 
            260                 265                 270         


Tyr Ser Val Gly Tyr Leu Ile Arg Leu Phe Ala Gly Ala Glu Ser Ile 
        275                 280                 285             


Ala Cys Asp Arg Asp Ser Gly Gln Leu Tyr Val Ile Gln Glu Gly Leu 
    290                 295                 300                 


Glu Ser Thr Gly Cys Thr Leu Val Phe Leu Val Leu Tyr Tyr Phe Gly 
305                 310                 315                 320 


Met Ala Ser Ser Leu Trp Trp Val Val Leu Thr Leu Thr Trp Phe Leu 
                325                 330                 335     


Ala Ala Gly Lys Lys Trp Gly His Glu Ala Ile Glu Ala Asn Ser Ser 
            340                 345                 350         


Tyr Phe His Leu Ala Ala Trp Ala Ile Pro Ala Val Lys Thr Ile Leu 
        355                 360                 365             


Ile Leu Val Met Arg Arg Val Ala Gly Asp Glu Leu Thr Gly Val Cys 
    370                 375                 380                 


Tyr Val Gly Ser Met Asp Val Asn Ala Leu Thr Gly Phe Val Leu Ile 
385                 390                 395                 400 


Pro Leu Ala Cys Tyr Leu Val Ile Gly Thr Ser Phe Ile Leu Ser Gly 
                405                 410                 415     


Phe Val Ala Leu Phe His Ile Arg Arg Val Met Lys Thr Gly Gly Glu 
            420                 425                 430         


Asn Thr Asp Lys Leu Glu Lys Leu Met Val Arg Ile Gly Leu Phe Ser 
        435                 440                 445             


Val Leu Tyr Thr Val Pro Ala Thr Cys Val Ile Ala Cys Tyr Phe Tyr 
    450                 455                 460                 


Glu Arg Leu Asn Met Asp Tyr Trp Lys Ile Leu Ala Ala Gln His Lys 
465                 470                 475                 480 


Cys Lys Met Asn Asn Gln Thr Lys Thr Leu Asp Cys Leu Met Ala Ala 
                485                 490                 495     


Ser Ile Pro Ala Val Glu Ile Phe Met Val Lys Ile Phe Met Leu Leu 
            500                 505                 510         


Val Val Gly Ile Thr Ser Gly Met Trp Ile Trp Thr Ser Lys Thr Leu 
        515                 520                 525             


Gln Ser Trp Gln Gln Val Cys Ser Arg Arg Leu Lys Lys Lys Ser Arg 
    530                 535                 540                 


Arg Lys Pro Ala Ser Val Ile Thr Ser Gly Gly Ile Tyr Lys Lys Ala 
545                 550                 555                 560 


Gln His Pro Gln Lys Thr His His Gly Lys Tyr Glu Ile Pro Ala Gln 
                565                 570                 575     


Ser Pro Thr Cys Val 
            580     


<210>  2740
<211>  2789
<212>  PRT
<213>  homo sapiens

<400>  2740

Met Arg Leu Gly Gly Gly Gln Leu Val Ser Glu Glu Leu Met Asn Leu 
1               5                   10                  15      


Gly Glu Ser Phe Ile Gln Thr Asn Asp Pro Ser Leu Lys Leu Phe Gln 
            20                  25                  30          


Cys Ala Val Cys Asn Lys Phe Thr Thr Asp Asn Leu Asp Met Leu Gly 
        35                  40                  45              


Leu His Met Asn Val Glu Arg Ser Leu Ser Glu Asp Glu Trp Lys Ala 
    50                  55                  60                  


Val Met Gly Asp Ser Tyr Gln Cys Lys Leu Cys Arg Tyr Asn Thr Gln 
65                  70                  75                  80  


Leu Lys Ala Asn Phe Gln Leu His Cys Lys Thr Asp Lys His Val Gln 
                85                  90                  95      


Lys Tyr Gln Leu Val Ala His Ile Lys Glu Gly Gly Lys Ala Asn Glu 
            100                 105                 110         


Trp Arg Leu Lys Cys Val Ala Ile Gly Asn Pro Val His Leu Lys Cys 
        115                 120                 125             


Asn Ala Cys Asp Tyr Tyr Thr Asn Ser Leu Glu Lys Leu Arg Leu His 
    130                 135                 140                 


Thr Val Asn Ser Arg His Glu Ala Ser Leu Lys Leu Tyr Lys His Leu 
145                 150                 155                 160 


Gln Gln His Glu Ser Gly Val Glu Gly Glu Ser Cys Tyr Tyr His Cys 
                165                 170                 175     


Val Leu Cys Asn Tyr Ser Thr Lys Ala Lys Leu Asn Leu Ile Gln His 
            180                 185                 190         


Val Arg Ser Met Lys His Gln Arg Ser Glu Ser Leu Arg Lys Leu Gln 
        195                 200                 205             


Arg Leu Gln Lys Gly Leu Pro Glu Glu Asp Glu Asp Leu Gly Gln Ile 
    210                 215                 220                 


Phe Thr Ile Arg Arg Cys Pro Ser Thr Asp Pro Glu Glu Ala Ile Glu 
225                 230                 235                 240 


Asp Val Glu Gly Pro Ser Glu Thr Ala Ala Asp Pro Glu Glu Leu Ala 
                245                 250                 255     


Lys Asp Gln Glu Gly Gly Ala Ser Ser Ser Gln Ala Glu Lys Glu Leu 
            260                 265                 270         


Thr Asp Ser Pro Ala Thr Ser Lys Arg Ile Ser Phe Pro Gly Ser Ser 
        275                 280                 285             


Glu Ser Pro Leu Ser Ser Lys Arg Pro Lys Thr Ala Glu Glu Ile Lys 
    290                 295                 300                 


Pro Glu Gln Met Tyr Gln Cys Pro Tyr Cys Lys Tyr Ser Asn Ala Asp 
305                 310                 315                 320 


Val Asn Arg Leu Arg Val His Ala Met Thr Gln His Ser Val Gln Pro 
                325                 330                 335     


Met Leu Arg Cys Pro Leu Cys Gln Asp Met Leu Asn Asn Lys Ile His 
            340                 345                 350         


Leu Gln Leu His Leu Thr His Leu His Ser Val Ala Pro Asp Cys Val 
        355                 360                 365             


Glu Lys Leu Ile Met Thr Val Thr Thr Pro Glu Met Val Met Pro Ser 
    370                 375                 380                 


Ser Met Phe Leu Pro Ala Ala Val Pro Asp Arg Asp Gly Asn Ser Asn 
385                 390                 395                 400 


Leu Glu Glu Ala Gly Lys Gln Pro Glu Thr Ser Glu Asp Leu Gly Lys 
                405                 410                 415     


Asn Ile Leu Pro Ser Ala Ser Thr Glu Gln Ser Gly Asp Leu Lys Pro 
            420                 425                 430         


Ser Pro Ala Asp Pro Gly Ser Val Arg Glu Asp Ser Gly Phe Ile Cys 
        435                 440                 445             


Trp Lys Lys Gly Cys Asn Gln Val Phe Lys Thr Ser Ala Ala Leu Gln 
    450                 455                 460                 


Thr His Phe Asn Glu Val His Ala Lys Arg Pro Gln Leu Pro Val Ser 
465                 470                 475                 480 


Asp Arg His Val Tyr Lys Tyr Arg Cys Asn Gln Cys Ser Leu Ala Phe 
                485                 490                 495     


Lys Thr Ile Glu Lys Leu Gln Leu His Ser Gln Tyr His Val Ile Arg 
            500                 505                 510         


Ala Ala Thr Met Cys Cys Leu Cys Gln Arg Ser Phe Arg Thr Phe Gln 
        515                 520                 525             


Ala Leu Lys Lys His Leu Glu Thr Ser His Leu Glu Leu Ser Glu Ala 
    530                 535                 540                 


Asp Ile Gln Gln Leu Tyr Gly Gly Leu Leu Ala Asn Gly Asp Leu Leu 
545                 550                 555                 560 


Ala Met Gly Asp Pro Thr Leu Ala Glu Asp His Thr Ile Ile Val Glu 
                565                 570                 575     


Glu Asp Lys Glu Glu Glu Ser Asp Leu Glu Asp Lys Gln Ser Pro Thr 
            580                 585                 590         


Gly Ser Asp Ser Gly Ser Val Gln Glu Asp Ser Gly Ser Glu Pro Lys 
        595                 600                 605             


Arg Ala Leu Pro Phe Arg Lys Gly Pro Asn Phe Thr Met Glu Lys Phe 
    610                 615                 620                 


Leu Asp Pro Ser Arg Pro Tyr Lys Cys Thr Val Cys Lys Glu Ser Phe 
625                 630                 635                 640 


Thr Gln Lys Asn Ile Leu Leu Val His Tyr Asn Ser Val Ser His Leu 
                645                 650                 655     


His Lys Leu Lys Arg Ala Leu Gln Glu Ser Ala Thr Gly Gln Pro Glu 
            660                 665                 670         


Pro Thr Ser Ser Pro Asp Asn Lys Pro Phe Lys Cys Asn Thr Cys Asn 
        675                 680                 685             


Val Ala Tyr Ser Gln Ser Ser Thr Leu Glu Ile His Met Arg Ser Val 
    690                 695                 700                 


Leu His Gln Thr Lys Ala Arg Ala Ala Lys Leu Glu Ala Ala Ser Gly 
705                 710                 715                 720 


Ser Ser Asn Gly Thr Gly Asn Ser Ser Ser Ile Ser Leu Ser Ser Ser 
                725                 730                 735     


Thr Pro Ser Pro Val Ser Thr Ser Gly Ser Asn Thr Phe Thr Thr Ser 
            740                 745                 750         


Asn Pro Ser Ser Ala Gly Ile Ala Pro Ser Ser Asn Leu Leu Ser Gln 
        755                 760                 765             


Val Pro Thr Glu Ser Val Gly Met Pro Pro Leu Gly Asn Pro Ile Gly 
    770                 775                 780                 


Ala Asn Ile Ala Ser Pro Ser Glu Pro Lys Glu Ala Asn Arg Lys Lys 
785                 790                 795                 800 


Leu Ala Asp Met Ile Ala Ser Arg Gln Gln Gln Gln Gln Gln Gln Gln 
                805                 810                 815     


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Ala Gln Thr Leu Ala 
            820                 825                 830         


Gln Ala Gln Ala Gln Val Gln Ala His Leu Gln Gln Glu Leu Gln Gln 
        835                 840                 845             


Gln Ala Ala Leu Ile Gln Ser Gln Leu Phe Asn Pro Thr Leu Leu Pro 
    850                 855                 860                 


His Phe Pro Met Thr Thr Glu Thr Leu Leu Gln Leu Gln Gln Gln Gln 
865                 870                 875                 880 


His Leu Leu Phe Pro Phe Tyr Ile Pro Ser Ala Glu Phe Gln Leu Asn 
                885                 890                 895     


Pro Glu Val Ser Leu Pro Val Thr Ser Gly Ala Leu Thr Leu Thr Gly 
            900                 905                 910         


Thr Gly Pro Gly Leu Leu Glu Asp Leu Lys Ala Gln Val Gln Val Pro 
        915                 920                 925             


Gln Gln Ser His Gln Gln Ile Leu Pro Gln Gln Gln Gln Asn Gln Leu 
    930                 935                 940                 


Ser Ile Ala Gln Ser His Ser Ala Leu Leu Gln Pro Ser Gln His Pro 
945                 950                 955                 960 


Glu Lys Lys Asn Lys Leu Val Ile Lys Glu Lys Glu Lys Glu Ser Gln 
                965                 970                 975     


Arg Glu Arg Asp Ser Ala Glu Gly Gly Glu Gly Asn Thr Gly Pro Lys 
            980                 985                 990         


Glu Thr Leu Pro Asp Ala Leu Lys  Ala Lys Glu Lys Lys  Glu Leu Ala 
        995                 1000                 1005             


Pro Gly  Gly Gly Ser Glu Pro  Ser Met Leu Pro Pro  Arg Ile Ala 
    1010                 1015                 1020             


Ser Asp  Ala Arg Gly Asn Ala  Thr Lys Ala Leu Leu  Glu Asn Phe 
    1025                 1030                 1035             


Gly Phe  Glu Leu Val Ile Gln  Tyr Asn Glu Asn Lys  Gln Lys Val 
    1040                 1045                 1050             


Gln Lys  Lys Asn Gly Lys Thr  Asp Gln Gly Glu Asn  Leu Glu Lys 
    1055                 1060                 1065             


Leu Glu  Cys Asp Ser Cys Gly  Lys Leu Phe Ser Asn  Ile Leu Ile 
    1070                 1075                 1080             


Leu Lys  Ser His Gln Glu His  Val His Gln Asn Tyr  Phe Pro Phe 
    1085                 1090                 1095             


Lys Gln  Leu Glu Arg Phe Ala  Lys Gln Tyr Arg Asp  His Tyr Asp 
    1100                 1105                 1110             


Lys Leu  Tyr Pro Leu Arg Pro  Gln Thr Pro Glu Pro  Pro Pro Pro 
    1115                 1120                 1125             


Pro Pro  Pro Pro Pro Pro Pro  Pro Leu Pro Ala Ala  Pro Pro Gln 
    1130                 1135                 1140             


Pro Ala  Ser Thr Pro Ala Ile  Pro Ala Ser Ala Pro  Pro Ile Thr 
    1145                 1150                 1155             


Ser Pro  Thr Ile Ala Pro Ala  Gln Pro Ser Val Pro  Leu Thr Gln 
    1160                 1165                 1170             


Leu Ser  Met Pro Met Glu Leu  Pro Ile Phe Ser Pro  Leu Met Met 
    1175                 1180                 1185             


Gln Thr  Met Pro Leu Gln Thr  Leu Pro Ala Gln Leu  Pro Pro Gln 
    1190                 1195                 1200             


Leu Gly  Pro Val Glu Pro Leu  Pro Ala Asp Leu Ala  Gln Leu Tyr 
    1205                 1210                 1215             


Gln His  Gln Leu Asn Pro Thr  Leu Leu Gln Gln Gln  Asn Lys Arg 
    1220                 1225                 1230             


Pro Arg  Thr Arg Ile Thr Asp  Asp Gln Leu Arg Val  Leu Arg Gln 
    1235                 1240                 1245             


Tyr Phe  Asp Ile Asn Asn Ser  Pro Ser Glu Glu Gln  Ile Lys Glu 
    1250                 1255                 1260             


Met Ala  Asp Lys Ser Gly Leu  Pro Gln Lys Val Ile  Lys His Trp 
    1265                 1270                 1275             


Phe Arg  Asn Thr Leu Phe Lys  Glu Arg Gln Arg Asn  Lys Asp Ser 
    1280                 1285                 1290             


Pro Tyr  Asn Phe Ser Asn Pro  Pro Ile Thr Ser Leu  Glu Glu Leu 
    1295                 1300                 1305             


Lys Ile  Asp Ser Arg Pro Pro  Ser Pro Glu Pro Pro  Lys Gln Glu 
    1310                 1315                 1320             


Tyr Trp  Gly Ser Lys Arg Ser  Ser Arg Thr Arg Phe  Thr Asp Tyr 
    1325                 1330                 1335             


Gln Leu  Arg Val Leu Gln Asp  Phe Phe Asp Ala Asn  Ala Tyr Pro 
    1340                 1345                 1350             


Lys Asp  Asp Glu Phe Glu Gln  Leu Ser Asn Leu Leu  Asn Leu Pro 
    1355                 1360                 1365             


Thr Arg  Val Ile Val Val Trp  Phe Gln Asn Ala Arg  Gln Lys Ala 
    1370                 1375                 1380             


Arg Lys  Asn Tyr Glu Asn Gln  Gly Glu Gly Lys Asp  Gly Glu Arg 
    1385                 1390                 1395             


Arg Glu  Leu Thr Asn Asp Arg  Tyr Ile Arg Thr Ser  Asn Leu Asn 
    1400                 1405                 1410             


Tyr Gln  Cys Lys Lys Cys Ser  Leu Val Phe Gln Arg  Ile Phe Asp 
    1415                 1420                 1425             


Leu Ile  Lys His Gln Lys Lys  Leu Cys Tyr Lys Asp  Glu Asp Glu 
    1430                 1435                 1440             


Glu Gly  Gln Asp Asp Ser Gln  Asn Glu Asp Ser Met  Asp Ala Met 
    1445                 1450                 1455             


Glu Ile  Leu Thr Pro Thr Ser  Ser Ser Cys Ser Thr  Pro Met Pro 
    1460                 1465                 1470             


Ser Gln  Ala Tyr Ser Ala Pro  Ala Pro Ser Ala Asn  Asn Thr Ala 
    1475                 1480                 1485             


Ser Ser  Ala Phe Leu Gln Leu  Thr Ala Glu Ala Glu  Glu Leu Ala 
    1490                 1495                 1500             


Thr Phe  Asn Ser Lys Thr Glu  Ala Gly Asp Glu Lys  Pro Lys Leu 
    1505                 1510                 1515             


Ala Glu  Ala Pro Ser Ala Gln  Pro Asn Gln Thr Gln  Glu Lys Gln 
    1520                 1525                 1530             


Gly Gln  Pro Lys Pro Glu Leu  Gln Gln Gln Glu Gln  Pro Glu Gln 
    1535                 1540                 1545             


Lys Thr  Asn Thr Pro Gln Gln  Lys Leu Pro Gln Leu  Val Ser Leu 
    1550                 1555                 1560             


Pro Ser  Leu Pro Gln Pro Pro  Pro Gln Ala Pro Pro  Pro Gln Cys 
    1565                 1570                 1575             


Pro Leu  Pro Gln Ser Ser Pro  Ser Pro Ser Gln Leu  Ser His Leu 
    1580                 1585                 1590             


Pro Leu  Lys Pro Leu His Thr  Ser Thr Pro Gln Gln  Leu Ala Asn 
    1595                 1600                 1605             


Leu Pro  Pro Gln Leu Ile Pro  Tyr Gln Cys Asp Gln  Cys Lys Leu 
    1610                 1615                 1620             


Ala Phe  Pro Ser Phe Glu His  Trp Gln Glu His Gln  Gln Leu His 
    1625                 1630                 1635             


Phe Leu  Ser Ala Gln Asn Gln  Phe Ile His Pro Gln  Phe Leu Asp 
    1640                 1645                 1650             


Arg Ser  Leu Asp Met Pro Phe  Met Leu Phe Asp Pro  Ser Asn Pro 
    1655                 1660                 1665             


Leu Leu  Ala Ser Gln Leu Leu  Ser Gly Ala Ile Pro  Gln Ile Pro 
    1670                 1675                 1680             


Ala Ser  Ser Ala Thr Ser Pro  Ser Thr Pro Thr Ser  Thr Met Asn 
    1685                 1690                 1695             


Thr Leu  Lys Arg Lys Leu Glu  Glu Lys Ala Ser Ala  Ser Pro Gly 
    1700                 1705                 1710             


Glu Asn  Asp Ser Gly Thr Gly  Gly Glu Glu Pro Gln  Arg Asp Lys 
    1715                 1720                 1725             


Arg Leu  Arg Thr Thr Ile Thr  Pro Glu Gln Leu Glu  Ile Leu Tyr 
    1730                 1735                 1740             


Gln Lys  Tyr Leu Leu Asp Ser  Asn Pro Thr Arg Lys  Met Leu Asp 
    1745                 1750                 1755             


His Ile  Ala His Glu Val Gly  Leu Lys Lys Arg Val  Val Gln Val 
    1760                 1765                 1770             


Trp Phe  Gln Asn Thr Arg Ala  Arg Glu Arg Lys Gly  Gln Phe Arg 
    1775                 1780                 1785             


Ala Val  Gly Pro Ala Gln Ala  His Arg Arg Cys Pro  Phe Cys Arg 
    1790                 1795                 1800             


Ala Leu  Phe Lys Ala Lys Thr  Ala Leu Glu Ala His  Ile Arg Ser 
    1805                 1810                 1815             


Arg His  Trp His Glu Ala Lys  Arg Ala Gly Tyr Asn  Leu Thr Leu 
    1820                 1825                 1830             


Ser Ala  Met Leu Leu Asp Cys  Asp Gly Gly Leu Gln  Met Lys Gly 
    1835                 1840                 1845             


Asp Ile  Phe Asp Gly Thr Ser  Phe Ser His Leu Pro  Pro Ser Ser 
    1850                 1855                 1860             


Ser Asp  Gly Gln Gly Val Pro  Leu Ser Pro Val Ser  Lys Thr Met 
    1865                 1870                 1875             


Glu Leu  Ser Pro Arg Thr Leu  Leu Ser Pro Ser Ser  Ile Lys Val 
    1880                 1885                 1890             


Glu Gly  Ile Glu Asp Phe Glu  Ser Pro Ser Met Ser  Ser Val Asn 
    1895                 1900                 1905             


Leu Asn  Phe Asp Gln Thr Lys  Leu Asp Asn Asp Asp  Cys Ser Ser 
    1910                 1915                 1920             


Val Asn  Thr Ala Ile Thr Asp  Thr Thr Thr Gly Asp  Glu Gly Asn 
    1925                 1930                 1935             


Ala Asp  Asn Asp Ser Ala Thr  Gly Ile Ala Thr Glu  Thr Lys Ser 
    1940                 1945                 1950             


Ser Ser  Ala Pro Asn Glu Gly  Leu Thr Lys Ala Ala  Met Met Ala 
    1955                 1960                 1965             


Met Ser  Glu Tyr Glu Asp Arg  Leu Ser Ser Gly Leu  Val Ser Pro 
    1970                 1975                 1980             


Ala Pro  Ser Phe Tyr Ser Lys  Glu Tyr Asp Asn Glu  Gly Thr Val 
    1985                 1990                 1995             


Asp Tyr  Ser Glu Thr Ser Ser  Leu Ala Asp Pro Cys  Ser Pro Ser 
    2000                 2005                 2010             


Pro Gly  Ala Ser Gly Ser Ala  Gly Lys Ser Gly Asp  Ser Gly Asp 
    2015                 2020                 2025             


Arg Pro  Gly Gln Lys Arg Phe  Arg Thr Gln Met Thr  Asn Leu Gln 
    2030                 2035                 2040             


Leu Lys  Val Leu Lys Ser Cys  Phe Asn Asp Tyr Arg  Thr Pro Thr 
    2045                 2050                 2055             


Met Leu  Glu Cys Glu Val Leu  Gly Asn Asp Ile Gly  Leu Pro Lys 
    2060                 2065                 2070             


Arg Val  Val Gln Val Trp Phe  Gln Asn Ala Arg Ala  Lys Glu Lys 
    2075                 2080                 2085             


Lys Ser  Lys Leu Ser Met Ala  Lys His Phe Gly Ile  Asn Gln Thr 
    2090                 2095                 2100             


Ser Tyr  Glu Gly Pro Lys Thr  Glu Cys Thr Leu Cys  Gly Ile Lys 
    2105                 2110                 2115             


Tyr Ser  Ala Arg Leu Ser Val  Arg Asp His Ile Phe  Ser Gln Gln 
    2120                 2125                 2130             


His Ile  Ser Lys Val Lys Asp  Thr Ile Gly Ser Gln  Leu Asp Lys 
    2135                 2140                 2145             


Glu Lys  Glu Tyr Phe Asp Pro  Ala Thr Val Arg Gln  Leu Met Ala 
    2150                 2155                 2160             


Gln Gln  Glu Leu Asp Arg Ile  Lys Lys Ala Asn Glu  Val Leu Gly 
    2165                 2170                 2175             


Leu Ala  Ala Gln Gln Gln Gly  Met Phe Asp Asn Thr  Pro Leu Gln 
    2180                 2185                 2190             


Ala Leu  Asn Leu Pro Thr Ala  Tyr Pro Ala Leu Gln  Gly Ile Pro 
    2195                 2200                 2205             


Pro Val  Leu Leu Pro Gly Leu  Asn Ser Pro Ser Leu  Pro Gly Phe 
    2210                 2215                 2220             


Thr Pro  Ser Asn Thr Ala Leu  Thr Ser Pro Lys Pro  Asn Leu Met 
    2225                 2230                 2235             


Gly Leu  Pro Ser Thr Thr Val  Pro Ser Pro Gly Leu  Pro Thr Ser 
    2240                 2245                 2250             


Gly Leu  Pro Asn Lys Pro Ser  Ser Ala Ser Leu Ser  Ser Pro Thr 
    2255                 2260                 2265             


Pro Ala  Gln Ala Thr Met Ala  Met Gly Pro Gln Gln  Pro Pro Gln 
    2270                 2275                 2280             


Gln Gln  Gln Gln Gln Gln Gln  Pro Gln Val Gln Gln  Pro Pro Pro 
    2285                 2290                 2295             


Pro Pro  Ala Ala Gln Pro Pro  Pro Thr Pro Gln Leu  Pro Leu Gln 
    2300                 2305                 2310             


Gln Gln  Gln Gln Arg Lys Asp  Lys Asp Ser Glu Lys  Val Lys Glu 
    2315                 2320                 2325             


Lys Glu  Lys Ala His Lys Gly  Lys Gly Glu Pro Leu  Pro Val Pro 
    2330                 2335                 2340             


Lys Lys  Glu Lys Gly Glu Ala  Pro Thr Ala Thr Ala  Ala Thr Ile 
    2345                 2350                 2355             


Ser Ala  Pro Leu Pro Thr Met  Glu Tyr Ala Val Asp  Pro Ala Gln 
    2360                 2365                 2370             


Leu Gln  Ala Leu Gln Ala Ala  Leu Thr Ser Asp Pro  Thr Ala Leu 
    2375                 2380                 2385             


Leu Thr  Ser Gln Phe Leu Pro  Tyr Phe Val Pro Gly  Phe Ser Pro 
    2390                 2395                 2400             


Tyr Tyr  Ala Pro Gln Ile Pro  Gly Ala Leu Gln Ser  Gly Tyr Leu 
    2405                 2410                 2415             


Gln Pro  Met Tyr Gly Met Glu  Gly Leu Phe Pro Tyr  Ser Pro Ala 
    2420                 2425                 2430             


Leu Ser  Gln Ala Leu Met Gly  Leu Ser Pro Gly Ser  Leu Leu Gln 
    2435                 2440                 2445             


Gln Tyr  Gln Gln Tyr Gln Gln  Ser Leu Gln Glu Ala  Ile Gln Gln 
    2450                 2455                 2460             


Gln Gln  Gln Arg Gln Leu Gln  Gln Gln Gln Gln Gln  Lys Val Gln 
    2465                 2470                 2475             


Gln Gln  Gln Pro Lys Ala Ser  Gln Thr Pro Val Pro  Pro Gly Ala 
    2480                 2485                 2490             


Pro Ser  Pro Asp Lys Asp Pro  Ala Lys Glu Ser Pro  Lys Pro Glu 
    2495                 2500                 2505             


Glu Gln  Lys Asn Thr Pro Arg  Glu Val Ser Pro Leu  Leu Pro Lys 
    2510                 2515                 2520             


Leu Pro  Glu Glu Pro Glu Ala  Glu Ser Lys Ser Ala  Asp Ser Leu 
    2525                 2530                 2535             


Tyr Asp  Pro Phe Ile Val Pro  Lys Val Gln Tyr Lys  Leu Val Cys 
    2540                 2545                 2550             


Arg Lys  Cys Gln Ala Gly Phe  Ser Asp Glu Glu Ala  Ala Arg Ser 
    2555                 2560                 2565             


His Leu  Lys Ser Leu Cys Phe  Phe Gly Gln Ser Val  Val Asn Leu 
    2570                 2575                 2580             


Gln Glu  Met Val Leu His Val  Pro Thr Gly Gly Gly  Gly Gly Gly 
    2585                 2590                 2595             


Ser Gly  Gly Gly Gly Gly Gly  Gly Gly Gly Gly Gly  Gly Gly Gly 
    2600                 2605                 2610             


Ser Tyr  His Cys Leu Ala Cys  Glu Ser Ala Leu Cys  Gly Glu Glu 
    2615                 2620                 2625             


Ala Leu  Ser Gln His Leu Glu  Ser Ala Leu His Lys  His Arg Thr 
    2630                 2635                 2640             


Ile Thr  Arg Ala Ala Arg Asn  Ala Lys Glu His Pro  Ser Leu Leu 
    2645                 2650                 2655             


Pro His  Ser Ala Cys Phe Pro  Asp Pro Ser Thr Ala  Ser Thr Ser 
    2660                 2665                 2670             


Gln Ser  Ala Ala His Ser Asn  Asp Ser Pro Pro Pro  Pro Ser Ala 
    2675                 2680                 2685             


Ala Ala  Pro Ser Ser Ala Ser  Pro His Ala Ser Arg  Lys Ser Trp 
    2690                 2695                 2700             


Pro Gln  Val Val Ser Arg Ala  Ser Ala Ala Lys Pro  Pro Ser Phe 
    2705                 2710                 2715             


Pro Pro  Leu Ser Ser Ser Ser  Thr Val Thr Ser Ser  Ser Cys Ser 
    2720                 2725                 2730             


Thr Ser  Gly Val Gln Pro Ser  Met Pro Thr Asp Asp  Tyr Ser Glu 
    2735                 2740                 2745             


Glu Ser  Asp Thr Asp Leu Ser  Gln Lys Ser Asp Gly  Pro Ala Ser 
    2750                 2755                 2760             


Pro Val  Glu Gly Pro Lys Asp  Pro Ser Cys Pro Lys  Asp Ser Gly 
    2765                 2770                 2775             


Leu Thr  Ser Val Gly Thr Asp  Thr Phe Arg Leu 
    2780                 2785                 


<210>  2741
<211>  310
<212>  PRT
<213>  homo sapiens

<400>  2741

Met Ser Gln Gln Leu Lys Lys Arg Ala Lys Thr Arg His Gln Lys Gly 
1               5                   10                  15      


Leu Gly Gly Arg Ala Pro Ser Gly Ala Lys Pro Arg Gln Gly Lys Ser 
            20                  25                  30          


Ser Gln Asp Leu Gln Ala Glu Ile Glu Pro Val Ser Ala Val Trp Ala 
        35                  40                  45              


Leu Cys Asp Gly Tyr Val Cys Tyr Glu Pro Gly Pro Gln Ala Leu Gly 
    50                  55                  60                  


Gly Asp Asp Phe Ser Asp Cys Tyr Ile Glu Cys Val Ile Arg Gly Glu 
65                  70                  75                  80  


Phe Ser Gln Pro Ile Leu Glu Glu Asp Ser Leu Phe Glu Ser Leu Glu 
                85                  90                  95      


Tyr Leu Lys Lys Gly Ser Glu Gln Gln Leu Ser Gln Lys Val Phe Glu 
            100                 105                 110         


Ala Ser Ser Leu Glu Cys Ser Leu Glu Tyr Met Lys Lys Gly Val Lys 
        115                 120                 125             


Lys Glu Leu Pro Gln Lys Ile Val Gly Glu Asn Ser Leu Glu Tyr Ser 
    130                 135                 140                 


Glu Tyr Met Thr Gly Lys Lys Leu Pro Pro Gly Gly Ile Pro Gly Ile 
145                 150                 155                 160 


Asp Leu Ser Asp Pro Lys Gln Leu Ala Glu Phe Ala Arg Lys Lys Pro 
                165                 170                 175     


Pro Ile Asn Lys Glu Tyr Asp Ser Leu Ser Ala Ile Ala Cys Pro Gln 
            180                 185                 190         


Ser Gly Cys Thr Arg Lys Leu Arg Asn Arg Ala Ala Leu Arg Lys His 
        195                 200                 205             


Leu Leu Ile His Gly Pro Arg Asp His Val Cys Ala Glu Cys Gly Lys 
    210                 215                 220                 


Ala Phe Val Glu Ser Ser Lys Leu Lys Arg His Phe Leu Val His Thr 
225                 230                 235                 240 


Gly Glu Lys Pro Phe Arg Cys Thr Phe Glu Gly Cys Gly Lys Arg Phe 
                245                 250                 255     


Ser Leu Asp Phe Asn Leu Arg Thr His Val Arg Ile His Thr Gly Glu 
            260                 265                 270         


Lys Arg Phe Val Cys Pro Phe Gln Gly Cys Asn Arg Arg Phe Ile Gln 
        275                 280                 285             


Ser Asn Asn Leu Lys Ala His Ile Leu Thr His Ala Asn Thr Asn Lys 
    290                 295                 300                 


Asn Glu Gln Glu Gly Lys 
305                 310 


<210>  2742
<211>  482
<212>  PRT
<213>  homo sapiens

<400>  2742

Met Val Met Glu Lys Pro Ser Pro Leu Leu Val Gly Arg Glu Phe Val 
1               5                   10                  15      


Arg Gln Tyr Tyr Thr Leu Leu Asn Lys Ala Pro Glu Tyr Leu His Arg 
            20                  25                  30          


Phe Tyr Gly Arg Asn Ser Ser Tyr Val His Gly Gly Val Asp Ala Ser 
        35                  40                  45              


Gly Lys Pro Gln Glu Ala Val Tyr Gly Gln Asn Asp Ile His His Lys 
    50                  55                  60                  


Val Leu Ser Leu Asn Phe Ser Glu Cys His Thr Lys Ile Arg His Val 
65                  70                  75                  80  


Asp Ala His Ala Thr Leu Ser Asp Gly Val Val Val Gln Val Met Gly 
                85                  90                  95      


Leu Leu Ser Asn Ser Gly Gln Pro Glu Arg Lys Phe Met Gln Thr Phe 
            100                 105                 110         


Val Leu Ala Pro Glu Gly Ser Val Pro Asn Lys Phe Tyr Val His Asn 
        115                 120                 125             


Asp Met Phe Arg Tyr Glu Asp Glu Val Phe Gly Asp Ser Glu Pro Glu 
    130                 135                 140                 


Leu Asp Glu Glu Ser Glu Asp Glu Val Glu Glu Glu Gln Glu Glu Arg 
145                 150                 155                 160 


Gln Pro Ser Pro Glu Pro Val Gln Glu Asn Ala Asn Ser Gly Tyr Tyr 
                165                 170                 175     


Glu Ala His Pro Val Thr Asn Gly Ile Glu Glu Pro Leu Glu Glu Ser 
            180                 185                 190         


Ser His Glu Pro Glu Pro Glu Pro Glu Ser Glu Thr Lys Thr Glu Glu 
        195                 200                 205             


Leu Lys Pro Gln Val Glu Glu Lys Asn Leu Glu Glu Leu Glu Glu Lys 
    210                 215                 220                 


Ser Thr Thr Pro Pro Pro Ala Glu Pro Val Ser Leu Pro Gln Glu Pro 
225                 230                 235                 240 


Pro Lys Ala Phe Ser Trp Ala Ser Val Thr Ser Lys Asn Leu Pro Pro 
                245                 250                 255     


Ser Gly Thr Val Ser Ser Ser Gly Ile Pro Pro His Val Lys Ala Pro 
            260                 265                 270         


Val Ser Gln Pro Arg Val Glu Ala Lys Pro Glu Val Gln Ser Gln Pro 
        275                 280                 285             


Pro Arg Val Arg Glu Gln Arg Pro Arg Glu Arg Pro Gly Phe Pro Pro 
    290                 295                 300                 


Arg Gly Pro Arg Pro Gly Arg Gly Asp Met Glu Gln Asn Asp Ser Asp 
305                 310                 315                 320 


Asn Arg Arg Ile Ile Arg Tyr Pro Asp Ser His Gln Leu Phe Val Gly 
                325                 330                 335     


Asn Leu Pro His Asp Ile Asp Glu Asn Glu Leu Lys Glu Phe Phe Met 
            340                 345                 350         


Ser Phe Gly Asn Val Val Glu Leu Arg Ile Asn Thr Lys Gly Val Gly 
        355                 360                 365             


Gly Lys Leu Pro Asn Phe Gly Phe Val Val Phe Asp Asp Ser Glu Pro 
    370                 375                 380                 


Val Gln Arg Ile Leu Ile Ala Lys Pro Ile Met Phe Arg Gly Glu Val 
385                 390                 395                 400 


Arg Leu Asn Val Glu Glu Lys Lys Thr Arg Ala Ala Arg Glu Arg Glu 
                405                 410                 415     


Thr Arg Gly Gly Gly Asp Asp Arg Arg Asp Ile Arg Arg Asn Asp Arg 
            420                 425                 430         


Gly Pro Gly Gly Pro Arg Gly Ile Val Gly Gly Gly Met Met Arg Asp 
        435                 440                 445             


Arg Asp Gly Arg Gly Pro Pro Pro Arg Gly Gly Met Ala Gln Lys Leu 
    450                 455                 460                 


Gly Ser Gly Arg Gly Thr Gly Gln Met Glu Gly Arg Phe Thr Gly Gln 
465                 470                 475                 480 


Arg Arg 
        


<210>  2743
<211>  449
<212>  PRT
<213>  homo sapiens

<400>  2743

Met Val Met Glu Lys Pro Ser Pro Leu Leu Val Gly Arg Glu Phe Val 
1               5                   10                  15      


Arg Gln Tyr Tyr Thr Leu Leu Asn Lys Ala Pro Glu Tyr Leu His Arg 
            20                  25                  30          


Phe Tyr Gly Arg Asn Ser Ser Tyr Val His Gly Gly Val Asp Ala Ser 
        35                  40                  45              


Gly Lys Pro Gln Glu Ala Val Tyr Gly Gln Asn Asp Ile His His Lys 
    50                  55                  60                  


Val Leu Ser Leu Asn Phe Ser Glu Cys His Thr Lys Ile Arg His Val 
65                  70                  75                  80  


Asp Ala His Ala Thr Leu Ser Asp Gly Val Val Val Gln Val Met Gly 
                85                  90                  95      


Leu Leu Ser Asn Ser Gly Gln Pro Glu Arg Lys Phe Met Gln Thr Phe 
            100                 105                 110         


Val Leu Ala Pro Glu Gly Ser Val Pro Asn Lys Phe Tyr Val His Asn 
        115                 120                 125             


Asp Met Phe Arg Tyr Glu Asp Glu Val Phe Gly Asp Ser Glu Pro Glu 
    130                 135                 140                 


Leu Asp Glu Glu Ser Glu Asp Glu Val Glu Glu Glu Gln Glu Glu Arg 
145                 150                 155                 160 


Gln Pro Ser Pro Glu Pro Val Gln Glu Asn Ala Asn Ser Gly Tyr Tyr 
                165                 170                 175     


Glu Ala His Pro Val Thr Asn Gly Ile Glu Glu Pro Leu Glu Glu Ser 
            180                 185                 190         


Ser His Glu Pro Glu Pro Glu Pro Glu Ser Glu Thr Lys Thr Glu Glu 
        195                 200                 205             


Leu Lys Pro Gln Val Glu Glu Lys Asn Leu Glu Glu Leu Glu Glu Lys 
    210                 215                 220                 


Ser Thr Thr Pro Pro Pro Ala Glu Pro Val Ser Leu Pro Gln Glu Pro 
225                 230                 235                 240 


Pro Lys Pro Arg Val Glu Ala Lys Pro Glu Val Gln Ser Gln Pro Pro 
                245                 250                 255     


Arg Val Arg Glu Gln Arg Pro Arg Glu Arg Pro Gly Phe Pro Pro Arg 
            260                 265                 270         


Gly Pro Arg Pro Gly Arg Gly Asp Met Glu Gln Asn Asp Ser Asp Asn 
        275                 280                 285             


Arg Arg Ile Ile Arg Tyr Pro Asp Ser His Gln Leu Phe Val Gly Asn 
    290                 295                 300                 


Leu Pro His Asp Ile Asp Glu Asn Glu Leu Lys Glu Phe Phe Met Ser 
305                 310                 315                 320 


Phe Gly Asn Val Val Glu Leu Arg Ile Asn Thr Lys Gly Val Gly Gly 
                325                 330                 335     


Lys Leu Pro Asn Phe Gly Phe Val Val Phe Asp Asp Ser Glu Pro Val 
            340                 345                 350         


Gln Arg Ile Leu Ile Ala Lys Pro Ile Met Phe Arg Gly Glu Val Arg 
        355                 360                 365             


Leu Asn Val Glu Glu Lys Lys Thr Arg Ala Ala Arg Glu Arg Glu Thr 
    370                 375                 380                 


Arg Gly Gly Gly Asp Asp Arg Arg Asp Ile Arg Arg Asn Asp Arg Gly 
385                 390                 395                 400 


Pro Gly Gly Pro Arg Gly Ile Val Gly Gly Gly Met Met Arg Asp Arg 
                405                 410                 415     


Asp Gly Arg Gly Pro Pro Pro Arg Gly Gly Met Ala Gln Lys Leu Gly 
            420                 425                 430         


Ser Gly Arg Gly Thr Gly Gln Met Glu Gly Arg Phe Thr Gly Gln Arg 
        435                 440                 445             


Arg 
    


<210>  2744
<211>  209
<212>  PRT
<213>  homo sapiens

<400>  2744

Met Ala Leu Leu Ala Glu His Leu Leu Lys Pro Leu Pro Ala Asp Lys 
1               5                   10                  15      


Gln Ile Glu Thr Gly Pro Phe Leu Glu Ala Val Ser His Leu Pro Pro 
            20                  25                  30          


Phe Phe Asp Cys Leu Gly Ser Pro Val Phe Thr Pro Ile Lys Ala Asp 
        35                  40                  45              


Ile Ser Gly Asn Ile Thr Lys Ile Lys Ala Val Tyr Asp Thr Asn Pro 
    50                  55                  60                  


Ala Lys Phe Arg Thr Leu Gln Asn Ile Leu Glu Val Glu Lys Glu Met 
65                  70                  75                  80  


Tyr Gly Ala Glu Trp Pro Lys Val Gly Ala Thr Leu Ala Leu Met Trp 
                85                  90                  95      


Leu Lys Arg Gly Leu Arg Phe Ile Gln Val Phe Leu Gln Ser Ile Cys 
            100                 105                 110         


Asp Gly Glu Arg Asp Glu Asn His Pro Asn Leu Ile Arg Val Asn Ala 
        115                 120                 125             


Thr Lys Ala Tyr Glu Met Ala Leu Lys Lys Tyr His Gly Trp Ile Val 
    130                 135                 140                 


Gln Lys Ile Phe Gln Ala Ala Leu Tyr Ala Ala Pro Tyr Lys Ser Asp 
145                 150                 155                 160 


Phe Leu Lys Ala Leu Ser Lys Gly Gln Asn Val Thr Glu Glu Glu Cys 
                165                 170                 175     


Leu Glu Lys Ile Arg Leu Phe Leu Val Asn Tyr Thr Ala Thr Ile Asp 
            180                 185                 190         


Val Ile Tyr Glu Met Tyr Thr Gln Met Asn Ala Glu Leu Asn Tyr Lys 
        195                 200                 205             


Val 
    


<210>  2745
<211>  447
<212>  PRT
<213>  homo sapiens

<400>  2745

Met Glu Asn Lys Lys Lys Asp Lys Asp Lys Ser Asp Asp Arg Met Ala 
1               5                   10                  15      


Arg Pro Ser Gly Arg Ser Gly His Asn Thr Arg Gly Thr Gly Ser Ser 
            20                  25                  30          


Ser Ser Gly Val Leu Met Val Gly Pro Asn Phe Arg Val Gly Lys Lys 
        35                  40                  45              


Ile Gly Cys Gly Asn Phe Gly Glu Leu Arg Leu Gly Lys Asn Leu Tyr 
    50                  55                  60                  


Thr Asn Glu Tyr Val Ala Ile Lys Leu Glu Pro Met Lys Ser Arg Ala 
65                  70                  75                  80  


Pro Gln Leu His Leu Glu Tyr Arg Phe Tyr Lys Gln Leu Gly Ser Gly 
                85                  90                  95      


Asp Gly Ile Pro Gln Val Tyr Tyr Phe Gly Pro Cys Gly Lys Tyr Asn 
            100                 105                 110         


Ala Met Val Leu Glu Leu Leu Gly Pro Ser Leu Glu Asp Leu Phe Asp 
        115                 120                 125             


Leu Cys Asp Arg Thr Phe Ser Leu Lys Thr Val Leu Met Ile Ala Ile 
    130                 135                 140                 


Gln Leu Ile Ser Arg Met Glu Tyr Val His Ser Lys Asn Leu Ile Tyr 
145                 150                 155                 160 


Arg Asp Val Lys Pro Glu Asn Phe Leu Ile Gly Arg Pro Gly Asn Lys 
                165                 170                 175     


Thr Gln Gln Val Ile His Ile Ile Asp Phe Gly Leu Ala Lys Glu Tyr 
            180                 185                 190         


Ile Asp Pro Glu Thr Lys Lys His Ile Pro Tyr Arg Glu His Lys Ser 
        195                 200                 205             


Leu Thr Gly Thr Ala Arg Tyr Met Ser Ile Asn Thr His Leu Gly Lys 
    210                 215                 220                 


Glu Gln Ser Arg Arg Asp Asp Leu Glu Ala Leu Gly His Met Phe Met 
225                 230                 235                 240 


Tyr Phe Leu Arg Gly Ser Leu Pro Trp Gln Gly Leu Lys Ala Asp Thr 
                245                 250                 255     


Leu Lys Glu Arg Tyr Gln Lys Ile Gly Asp Thr Lys Arg Ala Thr Pro 
            260                 265                 270         


Ile Glu Val Leu Cys Glu Asn Phe Pro Glu Met Ala Thr Tyr Leu Arg 
        275                 280                 285             


Tyr Val Arg Arg Leu Asp Phe Phe Glu Lys Pro Asp Tyr Asp Tyr Leu 
    290                 295                 300                 


Arg Lys Leu Phe Thr Asp Leu Phe Asp Arg Lys Gly Tyr Met Phe Asp 
305                 310                 315                 320 


Tyr Glu Tyr Asp Trp Ile Gly Lys Gln Leu Pro Thr Pro Val Gly Ala 
                325                 330                 335     


Val Gln Gln Asp Pro Ala Leu Ser Ser Asn Arg Glu Ala His Gln His 
            340                 345                 350         


Arg Asp Lys Met Gln Gln Ser Lys Asn Gln Ser Ala Asp His Arg Ala 
        355                 360                 365             


Ala Trp Asp Ser Gln Gln Ala Asn Pro His His Leu Arg Ala His Leu 
    370                 375                 380                 


Ala Ala Asp Arg His Gly Gly Ser Val Gln Val Val Ser Ser Thr Asn 
385                 390                 395                 400 


Gly Glu Leu Asn Thr Asp Asp Pro Thr Ala Gly Arg Ser Asn Ala Pro 
                405                 410                 415     


Ile Thr Ala Pro Thr Glu Val Glu Val Met Asp Glu Thr Lys Cys Cys 
            420                 425                 430         


Cys Phe Phe Lys Arg Arg Lys Arg Lys Thr Ile Gln Arg His Lys 
        435                 440                 445         


<210>  2746
<211>  1466
<212>  PRT
<213>  homo sapiens

<400>  2746

Met Met Ser Phe Val Gln Lys Gly Ser Trp Leu Leu Leu Ala Leu Leu 
1               5                   10                  15      


His Pro Thr Ile Ile Leu Ala Gln Gln Glu Ala Val Glu Gly Gly Cys 
            20                  25                  30          


Ser His Leu Gly Gln Ser Tyr Ala Asp Arg Asp Val Trp Lys Pro Glu 
        35                  40                  45              


Pro Cys Gln Ile Cys Val Cys Asp Ser Gly Ser Val Leu Cys Asp Asp 
    50                  55                  60                  


Ile Ile Cys Asp Asp Gln Glu Leu Asp Cys Pro Asn Pro Glu Ile Pro 
65                  70                  75                  80  


Phe Gly Glu Cys Cys Ala Val Cys Pro Gln Pro Pro Thr Ala Pro Thr 
                85                  90                  95      


Arg Pro Pro Asn Gly Gln Gly Pro Gln Gly Pro Lys Gly Asp Pro Gly 
            100                 105                 110         


Pro Pro Gly Ile Pro Gly Arg Asn Gly Asp Pro Gly Ile Pro Gly Gln 
        115                 120                 125             


Pro Gly Ser Pro Gly Ser Pro Gly Pro Pro Gly Ile Cys Glu Ser Cys 
    130                 135                 140                 


Pro Thr Gly Pro Gln Asn Tyr Ser Pro Gln Tyr Asp Ser Tyr Asp Val 
145                 150                 155                 160 


Lys Ser Gly Val Ala Val Gly Gly Leu Ala Gly Tyr Pro Gly Pro Ala 
                165                 170                 175     


Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly Thr Ser Gly His Pro Gly 
            180                 185                 190         


Ser Pro Gly Ser Pro Gly Tyr Gln Gly Pro Pro Gly Glu Pro Gly Gln 
        195                 200                 205             


Ala Gly Pro Ser Gly Pro Pro Gly Pro Pro Gly Ala Ile Gly Pro Ser 
    210                 215                 220                 


Gly Pro Ala Gly Lys Asp Gly Glu Ser Gly Arg Pro Gly Arg Pro Gly 
225                 230                 235                 240 


Glu Arg Gly Leu Pro Gly Pro Pro Gly Ile Lys Gly Pro Ala Gly Ile 
                245                 250                 255     


Pro Gly Phe Pro Gly Met Lys Gly His Arg Gly Phe Asp Gly Arg Asn 
            260                 265                 270         


Gly Glu Lys Gly Glu Thr Gly Ala Pro Gly Leu Lys Gly Glu Asn Gly 
        275                 280                 285             


Leu Pro Gly Glu Asn Gly Ala Pro Gly Pro Met Gly Pro Arg Gly Ala 
    290                 295                 300                 


Pro Gly Glu Arg Gly Arg Pro Gly Leu Pro Gly Ala Ala Gly Ala Arg 
305                 310                 315                 320 


Gly Asn Asp Gly Ala Arg Gly Ser Asp Gly Gln Pro Gly Pro Pro Gly 
                325                 330                 335     


Pro Pro Gly Thr Ala Gly Phe Pro Gly Ser Pro Gly Ala Lys Gly Glu 
            340                 345                 350         


Val Gly Pro Ala Gly Ser Pro Gly Ser Asn Gly Ala Pro Gly Gln Arg 
        355                 360                 365             


Gly Glu Pro Gly Pro Gln Gly His Ala Gly Ala Gln Gly Pro Pro Gly 
    370                 375                 380                 


Pro Pro Gly Ile Asn Gly Ser Pro Gly Gly Lys Gly Glu Met Gly Pro 
385                 390                 395                 400 


Ala Gly Ile Pro Gly Ala Pro Gly Leu Met Gly Ala Arg Gly Pro Pro 
                405                 410                 415     


Gly Pro Ala Gly Ala Asn Gly Ala Pro Gly Leu Arg Gly Gly Ala Gly 
            420                 425                 430         


Glu Pro Gly Lys Asn Gly Ala Lys Gly Glu Pro Gly Pro Arg Gly Glu 
        435                 440                 445             


Arg Gly Glu Ala Gly Ile Pro Gly Val Pro Gly Ala Lys Gly Glu Asp 
    450                 455                 460                 


Gly Lys Asp Gly Ser Pro Gly Glu Pro Gly Ala Asn Gly Leu Pro Gly 
465                 470                 475                 480 


Ala Ala Gly Glu Arg Gly Ala Pro Gly Phe Arg Gly Pro Ala Gly Pro 
                485                 490                 495     


Asn Gly Ile Pro Gly Glu Lys Gly Pro Ala Gly Glu Arg Gly Ala Pro 
            500                 505                 510         


Gly Pro Ala Gly Pro Arg Gly Ala Ala Gly Glu Pro Gly Arg Asp Gly 
        515                 520                 525             


Val Pro Gly Gly Pro Gly Met Arg Gly Met Pro Gly Ser Pro Gly Gly 
    530                 535                 540                 


Pro Gly Ser Asp Gly Lys Pro Gly Pro Pro Gly Ser Gln Gly Glu Ser 
545                 550                 555                 560 


Gly Arg Pro Gly Pro Pro Gly Pro Ser Gly Pro Arg Gly Gln Pro Gly 
                565                 570                 575     


Val Met Gly Phe Pro Gly Pro Lys Gly Asn Asp Gly Ala Pro Gly Lys 
            580                 585                 590         


Asn Gly Glu Arg Gly Gly Pro Gly Gly Pro Gly Pro Gln Gly Pro Pro 
        595                 600                 605             


Gly Lys Asn Gly Glu Thr Gly Pro Gln Gly Pro Pro Gly Pro Thr Gly 
    610                 615                 620                 


Pro Gly Gly Asp Lys Gly Asp Thr Gly Pro Pro Gly Pro Gln Gly Leu 
625                 630                 635                 640 


Gln Gly Leu Pro Gly Thr Gly Gly Pro Pro Gly Glu Asn Gly Lys Pro 
                645                 650                 655     


Gly Glu Pro Gly Pro Lys Gly Asp Ala Gly Ala Pro Gly Ala Pro Gly 
            660                 665                 670         


Gly Lys Gly Asp Ala Gly Ala Pro Gly Glu Arg Gly Pro Pro Gly Leu 
        675                 680                 685             


Ala Gly Ala Pro Gly Leu Arg Gly Gly Ala Gly Pro Pro Gly Pro Glu 
    690                 695                 700                 


Gly Gly Lys Gly Ala Ala Gly Pro Pro Gly Pro Pro Gly Ala Ala Gly 
705                 710                 715                 720 


Thr Pro Gly Leu Gln Gly Met Pro Gly Glu Arg Gly Gly Leu Gly Ser 
                725                 730                 735     


Pro Gly Pro Lys Gly Asp Lys Gly Glu Pro Gly Gly Pro Gly Ala Asp 
            740                 745                 750         


Gly Val Pro Gly Lys Asp Gly Pro Arg Gly Pro Thr Gly Pro Ile Gly 
        755                 760                 765             


Pro Pro Gly Pro Ala Gly Gln Pro Gly Asp Lys Gly Glu Gly Gly Ala 
    770                 775                 780                 


Pro Gly Leu Pro Gly Ile Ala Gly Pro Arg Gly Ser Pro Gly Glu Arg 
785                 790                 795                 800 


Gly Glu Thr Gly Pro Pro Gly Pro Ala Gly Phe Pro Gly Ala Pro Gly 
                805                 810                 815     


Gln Asn Gly Glu Pro Gly Gly Lys Gly Glu Arg Gly Ala Pro Gly Glu 
            820                 825                 830         


Lys Gly Glu Gly Gly Pro Pro Gly Val Ala Gly Pro Pro Gly Gly Ser 
        835                 840                 845             


Gly Pro Ala Gly Pro Pro Gly Pro Gln Gly Val Lys Gly Glu Arg Gly 
    850                 855                 860                 


Ser Pro Gly Gly Pro Gly Ala Ala Gly Phe Pro Gly Ala Arg Gly Leu 
865                 870                 875                 880 


Pro Gly Pro Pro Gly Ser Asn Gly Asn Pro Gly Pro Pro Gly Pro Ser 
                885                 890                 895     


Gly Ser Pro Gly Lys Asp Gly Pro Pro Gly Pro Ala Gly Asn Thr Gly 
            900                 905                 910         


Ala Pro Gly Ser Pro Gly Val Ser Gly Pro Lys Gly Asp Ala Gly Gln 
        915                 920                 925             


Pro Gly Glu Lys Gly Ser Pro Gly Ala Gln Gly Pro Pro Gly Ala Pro 
    930                 935                 940                 


Gly Pro Leu Gly Ile Ala Gly Ile Thr Gly Ala Arg Gly Leu Ala Gly 
945                 950                 955                 960 


Pro Pro Gly Met Pro Gly Pro Arg Gly Ser Pro Gly Pro Gln Gly Val 
                965                 970                 975     


Lys Gly Glu Ser Gly Lys Pro Gly Ala Asn Gly Leu Ser Gly Glu Arg 
            980                 985                 990         


Gly Pro Pro Gly Pro Gln Gly Leu  Pro Gly Leu Ala Gly  Thr Ala Gly 
        995                 1000                 1005             


Glu Pro  Gly Arg Asp Gly Asn  Pro Gly Ser Asp Gly  Leu Pro Gly 
    1010                 1015                 1020             


Arg Asp  Gly Ser Pro Gly Gly  Lys Gly Asp Arg Gly  Glu Asn Gly 
    1025                 1030                 1035             


Ser Pro  Gly Ala Pro Gly Ala  Pro Gly His Pro Gly  Pro Pro Gly 
    1040                 1045                 1050             


Pro Val  Gly Pro Ala Gly Lys  Ser Gly Asp Arg Gly  Glu Ser Gly 
    1055                 1060                 1065             


Pro Ala  Gly Pro Ala Gly Ala  Pro Gly Pro Ala Gly  Ser Arg Gly 
    1070                 1075                 1080             


Ala Pro  Gly Pro Gln Gly Pro  Arg Gly Asp Lys Gly  Glu Thr Gly 
    1085                 1090                 1095             


Glu Arg  Gly Ala Ala Gly Ile  Lys Gly His Arg Gly  Phe Pro Gly 
    1100                 1105                 1110             


Asn Pro  Gly Ala Pro Gly Ser  Pro Gly Pro Ala Gly  Gln Gln Gly 
    1115                 1120                 1125             


Ala Ile  Gly Ser Pro Gly Pro  Ala Gly Pro Arg Gly  Pro Val Gly 
    1130                 1135                 1140             


Pro Ser  Gly Pro Pro Gly Lys  Asp Gly Thr Ser Gly  His Pro Gly 
    1145                 1150                 1155             


Pro Ile  Gly Pro Pro Gly Pro  Arg Gly Asn Arg Gly  Glu Arg Gly 
    1160                 1165                 1170             


Ser Glu  Gly Ser Pro Gly His  Pro Gly Gln Pro Gly  Pro Pro Gly 
    1175                 1180                 1185             


Pro Pro  Gly Ala Pro Gly Pro  Cys Cys Gly Gly Val  Gly Ala Ala 
    1190                 1195                 1200             


Ala Ile  Ala Gly Ile Gly Gly  Glu Lys Ala Gly Gly  Phe Ala Pro 
    1205                 1210                 1215             


Tyr Tyr  Gly Asp Glu Pro Met  Asp Phe Lys Ile Asn  Thr Asp Glu 
    1220                 1225                 1230             


Ile Met  Thr Ser Leu Lys Ser  Val Asn Gly Gln Ile  Glu Ser Leu 
    1235                 1240                 1245             


Ile Ser  Pro Asp Gly Ser Arg  Lys Asn Pro Ala Arg  Asn Cys Arg 
    1250                 1255                 1260             


Asp Leu  Lys Phe Cys His Pro  Glu Leu Lys Ser Gly  Glu Tyr Trp 
    1265                 1270                 1275             


Val Asp  Pro Asn Gln Gly Cys  Lys Leu Asp Ala Ile  Lys Val Phe 
    1280                 1285                 1290             


Cys Asn  Met Glu Thr Gly Glu  Thr Cys Ile Ser Ala  Asn Pro Leu 
    1295                 1300                 1305             


Asn Val  Pro Arg Lys His Trp  Trp Thr Asp Ser Ser  Ala Glu Lys 
    1310                 1315                 1320             


Lys His  Val Trp Phe Gly Glu  Ser Met Asp Gly Gly  Phe Gln Phe 
    1325                 1330                 1335             


Ser Tyr  Gly Asn Pro Glu Leu  Pro Glu Asp Val Leu  Asp Val Gln 
    1340                 1345                 1350             


Leu Ala  Phe Leu Arg Leu Leu  Ser Ser Arg Ala Ser  Gln Asn Ile 
    1355                 1360                 1365             


Thr Tyr  His Cys Lys Asn Ser  Ile Ala Tyr Met Asp  Gln Ala Ser 
    1370                 1375                 1380             


Gly Asn  Val Lys Lys Ala Leu  Lys Leu Met Gly Ser  Asn Glu Gly 
    1385                 1390                 1395             


Glu Phe  Lys Ala Glu Gly Asn  Ser Lys Phe Thr Tyr  Thr Val Leu 
    1400                 1405                 1410             


Glu Asp  Gly Cys Thr Lys His  Thr Gly Glu Trp Ser  Lys Thr Val 
    1415                 1420                 1425             


Phe Glu  Tyr Arg Thr Arg Lys  Ala Val Arg Leu Pro  Ile Val Asp 
    1430                 1435                 1440             


Ile Ala  Pro Tyr Asp Ile Gly  Gly Pro Asp Gln Glu  Phe Gly Val 
    1445                 1450                 1455             


Asp Val  Gly Pro Val Cys Phe  Leu 
    1460                 1465     


<210>  2747
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  2747

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  2748
<211>  332
<212>  PRT
<213>  homo sapiens

<400>  2748

Met Gly Ala Gln Phe Ser Lys Thr Ala Ala Lys Gly Glu Ala Ala Ala 
1               5                   10                  15      


Glu Arg Pro Gly Glu Ala Ala Val Ala Ser Ser Pro Ser Lys Ala Asn 
            20                  25                  30          


Gly Gln Glu Asn Gly His Val Lys Val Asn Gly Asp Ala Ser Pro Ala 
        35                  40                  45              


Ala Ala Glu Ser Gly Ala Lys Glu Glu Leu Gln Ala Asn Gly Ser Ala 
    50                  55                  60                  


Pro Ala Ala Asp Lys Glu Glu Pro Ala Ala Ala Gly Ser Gly Ala Ala 
65                  70                  75                  80  


Ser Pro Ser Ala Ala Glu Lys Gly Glu Pro Ala Ala Ala Ala Ala Pro 
                85                  90                  95      


Glu Ala Gly Ala Ser Pro Val Glu Lys Glu Ala Pro Ala Glu Gly Glu 
            100                 105                 110         


Ala Ala Glu Pro Gly Ser Pro Thr Ala Ala Glu Gly Glu Ala Ala Ser 
        115                 120                 125             


Ala Ala Ser Ser Thr Ser Ser Pro Lys Ala Glu Asp Gly Ala Thr Pro 
    130                 135                 140                 


Ser Pro Ser Asn Glu Thr Pro Lys Lys Lys Lys Lys Arg Phe Ser Phe 
145                 150                 155                 160 


Lys Lys Ser Phe Lys Leu Ser Gly Phe Ser Phe Lys Lys Asn Lys Lys 
                165                 170                 175     


Glu Ala Gly Glu Gly Gly Glu Ala Glu Ala Pro Ala Ala Glu Gly Gly 
            180                 185                 190         


Lys Asp Glu Ala Ala Gly Gly Ala Ala Ala Ala Ala Ala Glu Ala Gly 
        195                 200                 205             


Ala Ala Ser Gly Glu Gln Ala Ala Ala Pro Gly Glu Glu Ala Ala Ala 
    210                 215                 220                 


Gly Glu Glu Gly Ala Ala Gly Gly Asp Pro Gln Glu Ala Lys Pro Gln 
225                 230                 235                 240 


Glu Ala Ala Val Ala Pro Glu Lys Pro Pro Ala Ser Asp Glu Thr Lys 
                245                 250                 255     


Ala Ala Glu Glu Pro Ser Lys Val Glu Glu Lys Lys Ala Glu Glu Ala 
            260                 265                 270         


Gly Ala Ser Ala Ala Ala Cys Glu Ala Pro Ser Ala Ala Gly Pro Gly 
        275                 280                 285             


Ala Pro Pro Glu Gln Glu Ala Ala Pro Ala Glu Glu Pro Ala Ala Ala 
    290                 295                 300                 


Ala Ala Ser Ser Ala Cys Ala Ala Pro Ser Gln Glu Ala Gln Pro Glu 
305                 310                 315                 320 


Cys Ser Pro Glu Ala Pro Pro Ala Glu Ala Ala Glu 
                325                 330         


<210>  2749
<211>  423
<212>  PRT
<213>  homo sapiens

<400>  2749

Met Ala Met Val Val Ser Ser Trp Arg Asp Pro Gln Asp Asp Val Ala 
1               5                   10                  15      


Gly Gly Asn Pro Gly Gly Pro Asn Pro Ala Ala Gln Ala Ala Arg Gly 
            20                  25                  30          


Gly Gly Gly Gly Ala Gly Glu Gln Gln Gln Gln Ala Gly Ser Gly Ala 
        35                  40                  45              


Pro His Thr Pro Gln Thr Pro Gly Gln Pro Gly Ala Pro Ala Thr Pro 
    50                  55                  60                  


Gly Thr Ala Gly Asp Lys Gly Gln Gly Pro Pro Gly Ser Gly Gln Ser 
65                  70                  75                  80  


Gln Gln His Ile Glu Cys Val Val Cys Gly Asp Lys Ser Ser Gly Lys 
                85                  90                  95      


His Tyr Gly Gln Phe Thr Cys Glu Gly Cys Lys Ser Phe Phe Lys Arg 
            100                 105                 110         


Ser Val Arg Arg Asn Leu Thr Tyr Thr Cys Arg Ala Asn Arg Asn Cys 
        115                 120                 125             


Pro Ile Asp Gln His His Arg Asn Gln Cys Gln Tyr Cys Arg Leu Lys 
    130                 135                 140                 


Lys Cys Leu Lys Val Gly Met Arg Arg Glu Ala Val Gln Arg Gly Arg 
145                 150                 155                 160 


Met Pro Pro Thr Gln Pro Asn Pro Gly Gln Tyr Ala Leu Thr Asn Gly 
                165                 170                 175     


Asp Pro Leu Asn Gly His Cys Tyr Leu Ser Gly Tyr Ile Ser Leu Leu 
            180                 185                 190         


Leu Arg Ala Glu Pro Tyr Pro Thr Ser Arg Tyr Gly Ser Gln Cys Met 
        195                 200                 205             


Gln Pro Asn Asn Ile Met Gly Ile Glu Asn Ile Cys Glu Leu Ala Ala 
    210                 215                 220                 


Arg Leu Leu Phe Ser Ala Val Glu Trp Ala Arg Asn Ile Pro Phe Phe 
225                 230                 235                 240 


Pro Asp Leu Gln Ile Thr Asp Gln Val Ser Leu Leu Arg Leu Thr Trp 
                245                 250                 255     


Ser Glu Leu Phe Val Leu Asn Ala Ala Gln Cys Ser Met Pro Leu His 
            260                 265                 270         


Val Ala Pro Leu Leu Ala Ala Ala Gly Leu His Ala Ser Pro Met Ser 
        275                 280                 285             


Ala Asp Arg Val Val Ala Phe Met Asp His Ile Arg Ile Phe Gln Glu 
    290                 295                 300                 


Gln Val Glu Lys Leu Lys Ala Leu His Val Asp Ser Ala Glu Tyr Ser 
305                 310                 315                 320 


Cys Leu Lys Ala Ile Val Leu Phe Thr Ser Asp Ala Cys Gly Leu Ser 
                325                 330                 335     


Asp Ala Ala His Ile Glu Ser Leu Gln Glu Lys Ser Gln Cys Ala Leu 
            340                 345                 350         


Glu Glu Tyr Val Arg Ser Gln Tyr Pro Asn Gln Pro Ser Arg Phe Gly 
        355                 360                 365             


Lys Leu Leu Leu Arg Leu Pro Ser Leu Arg Thr Val Ser Ser Ser Val 
    370                 375                 380                 


Ile Glu Gln Leu Phe Phe Val Arg Leu Val Gly Lys Thr Pro Ile Glu 
385                 390                 395                 400 


Thr Leu Ile Arg Asp Met Leu Leu Ser Gly Ser Ser Phe Asn Trp Pro 
                405                 410                 415     


Tyr Met Ser Ile Gln Cys Ser 
            420             


<210>  2750
<211>  404
<212>  PRT
<213>  homo sapiens

<400>  2750

Met Ala Met Val Thr Gly Gly Trp Gly Gly Pro Gly Gly Asp Thr Asn 
1               5                   10                  15      


Gly Val Asp Lys Ala Gly Gly Tyr Pro Arg Ala Ala Glu Asp Asp Ser 
            20                  25                  30          


Ala Ser Pro Pro Gly Ala Ala Ser Asp Ala Glu Pro Gly Asp Glu Glu 
        35                  40                  45              


Arg Pro Gly Leu Gln Val Asp Cys Val Val Cys Gly Asp Lys Ser Ser 
    50                  55                  60                  


Gly Lys His Tyr Gly Val Phe Thr Cys Glu Gly Cys Lys Ser Phe Phe 
65                  70                  75                  80  


Lys Arg Ser Ile Arg Arg Asn Leu Ser Tyr Thr Cys Arg Ser Asn Arg 
                85                  90                  95      


Asp Cys Gln Ile Asp Gln His His Arg Asn Gln Cys Gln Tyr Cys Arg 
            100                 105                 110         


Leu Lys Lys Cys Phe Arg Val Gly Met Arg Lys Glu Ala Val Gln Arg 
        115                 120                 125             


Gly Arg Ile Pro His Ser Leu Pro Gly Ala Val Ala Ala Ser Ser Gly 
    130                 135                 140                 


Ser Pro Pro Gly Ser Ala Leu Ala Ala Val Ala Ser Gly Gly Asp Leu 
145                 150                 155                 160 


Phe Pro Gly Gln Pro Val Ser Glu Leu Ile Ala Gln Leu Leu Arg Ala 
                165                 170                 175     


Glu Pro Tyr Pro Ala Ala Ala Gly Arg Phe Gly Ala Gly Gly Gly Ala 
            180                 185                 190         


Ala Gly Ala Val Leu Gly Ile Asp Asn Val Cys Glu Leu Ala Ala Arg 
        195                 200                 205             


Leu Leu Phe Ser Thr Val Glu Trp Ala Arg His Ala Pro Phe Phe Pro 
    210                 215                 220                 


Glu Leu Pro Val Ala Asp Gln Val Ala Leu Leu Arg Leu Ser Trp Ser 
225                 230                 235                 240 


Glu Leu Phe Val Leu Asn Ala Ala Gln Ala Ala Leu Pro Leu His Thr 
                245                 250                 255     


Ala Pro Leu Leu Ala Ala Ala Gly Leu His Ala Ala Pro Met Ala Ala 
            260                 265                 270         


Glu Arg Ala Val Ala Phe Met Asp Gln Val Arg Ala Phe Gln Glu Gln 
        275                 280                 285             


Val Asp Lys Leu Gly Arg Leu Gln Val Asp Ser Ala Glu Tyr Gly Cys 
    290                 295                 300                 


Leu Lys Ala Ile Ala Leu Phe Thr Pro Asp Ala Cys Gly Leu Ser Asp 
305                 310                 315                 320 


Pro Ala His Val Glu Ser Leu Gln Glu Lys Ala Gln Val Ala Leu Thr 
                325                 330                 335     


Glu Tyr Val Arg Ala Gln Tyr Pro Ser Gln Pro Gln Arg Phe Gly Arg 
            340                 345                 350         


Leu Leu Leu Arg Leu Pro Ala Leu Arg Ala Val Pro Ala Ser Leu Ile 
        355                 360                 365             


Ser Gln Leu Phe Phe Met Arg Leu Val Gly Lys Thr Pro Ile Glu Thr 
    370                 375                 380                 


Leu Ile Arg Asp Met Leu Leu Ser Gly Ser Thr Phe Asn Trp Pro Tyr 
385                 390                 395                 400 


Gly Ser Gly Gln 
                


<210>  2751
<211>  708
<212>  PRT
<213>  homo sapiens

<400>  2751

Met Arg Glu Arg Ile Trp Ala Pro Pro Leu Leu Leu Leu Leu Pro Leu 
1               5                   10                  15      


Leu Leu Pro Pro Pro Leu Trp Gly Gly Pro Pro Asp Ser Pro Arg Arg 
            20                  25                  30          


Glu Leu Glu Leu Glu Pro Gly Pro Leu Gln Pro Phe Asp Leu Leu Tyr 
        35                  40                  45              


Ala Ser Gly Ala Ala Ala Tyr Tyr Ser Gly Asp Tyr Glu Arg Ala Val 
    50                  55                  60                  


Arg Asp Leu Glu Ala Ala Leu Arg Ser His Arg Arg Leu Arg Glu Ile 
65                  70                  75                  80  


Arg Thr Arg Cys Ala Arg His Cys Ala Ala Arg His Pro Leu Pro Pro 
                85                  90                  95      


Pro Pro Pro Gly Glu Gly Pro Gly Ala Glu Leu Pro Leu Phe Arg Ser 
            100                 105                 110         


Leu Leu Gly Arg Ala Arg Cys Tyr Arg Ser Cys Glu Thr Gln Arg Leu 
        115                 120                 125             


Gly Gly Pro Ala Ser Arg His Arg Val Ser Glu Asp Val Arg Ser Asp 
    130                 135                 140                 


Phe Gln Arg Arg Val Pro Tyr Asn Tyr Leu Gln Arg Ala Tyr Ile Lys 
145                 150                 155                 160 


Leu Asn Gln Leu Glu Lys Ala Val Glu Ala Ala His Thr Phe Phe Val 
                165                 170                 175     


Ala Asn Pro Glu His Met Glu Met Gln Gln Asn Ile Glu Asn Tyr Arg 
            180                 185                 190         


Ala Thr Ala Gly Val Glu Ala Leu Gln Leu Val Asp Arg Glu Ala Lys 
        195                 200                 205             


Pro His Met Glu Ser Tyr Asn Ala Gly Val Lys His Tyr Glu Ala Asp 
    210                 215                 220                 


Asp Phe Glu Met Ala Ile Arg His Phe Glu Gln Ala Leu Arg Glu Tyr 
225                 230                 235                 240 


Phe Val Glu Asp Thr Glu Cys Arg Thr Leu Cys Glu Gly Pro Gln Arg 
                245                 250                 255     


Phe Glu Glu Tyr Glu Tyr Leu Gly Tyr Lys Ala Gly Leu Tyr Glu Ala 
            260                 265                 270         


Ile Ala Asp His Tyr Met Gln Val Leu Val Cys Gln His Glu Cys Val 
        275                 280                 285             


Arg Glu Leu Ala Thr Arg Pro Gly Arg Leu Ser Pro Ile Glu Asn Phe 
    290                 295                 300                 


Leu Pro Leu His Tyr Asp Tyr Leu Gln Phe Ala Tyr Tyr Arg Val Gly 
305                 310                 315                 320 


Glu Tyr Val Lys Ala Leu Glu Cys Ala Lys Ala Tyr Leu Leu Cys His 
                325                 330                 335     


Pro Asp Asp Glu Asp Val Leu Asp Asn Val Asp Tyr Tyr Glu Ser Leu 
            340                 345                 350         


Leu Asp Asp Ser Ile Asp Pro Ala Ser Ile Glu Ala Arg Glu Asp Leu 
        355                 360                 365             


Thr Met Phe Val Lys Arg His Lys Leu Glu Ser Glu Leu Ile Lys Ser 
    370                 375                 380                 


Ala Ala Glu Gly Leu Gly Phe Ser Tyr Thr Glu Pro Asn Tyr Trp Ile 
385                 390                 395                 400 


Arg Tyr Gly Gly Arg Gln Asp Glu Asn Arg Val Pro Ser Gly Val Asn 
                405                 410                 415     


Val Glu Gly Ala Glu Val His Gly Phe Ser Met Gly Lys Lys Leu Ser 
            420                 425                 430         


Pro Lys Ile Asp Arg Asp Leu Arg Glu Gly Gly Pro Leu Leu Tyr Glu 
        435                 440                 445             


Asn Ile Thr Phe Val Tyr Asn Ser Glu Gln Leu Asn Gly Thr Gln Arg 
    450                 455                 460                 


Val Leu Leu Asp Asn Val Leu Ser Glu Glu Gln Cys Arg Glu Leu His 
465                 470                 475                 480 


Ser Val Ala Ser Gly Ile Met Leu Val Gly Asp Gly Tyr Arg Gly Lys 
                485                 490                 495     


Thr Ser Pro His Thr Pro Asn Glu Lys Phe Glu Gly Ala Thr Val Leu 
            500                 505                 510         


Lys Ala Leu Lys Ser Gly Tyr Glu Gly Arg Val Pro Leu Lys Ser Ala 
        515                 520                 525             


Arg Leu Phe Tyr Asp Ile Ser Glu Lys Ala Arg Arg Ile Val Glu Ser 
    530                 535                 540                 


Tyr Phe Met Leu Asn Ser Thr Leu Tyr Phe Ser Tyr Thr His Met Val 
545                 550                 555                 560 


Cys Arg Thr Ala Leu Ser Gly Gln Gln Asp Arg Arg Asn Asp Leu Ser 
                565                 570                 575     


His Pro Ile His Ala Asp Asn Cys Leu Leu Asp Pro Glu Ala Asn Glu 
            580                 585                 590         


Cys Trp Lys Glu Pro Pro Ala Tyr Thr Phe Arg Asp Tyr Ser Ala Leu 
        595                 600                 605             


Leu Tyr Met Asn Asp Asp Phe Glu Gly Gly Glu Phe Ile Phe Thr Glu 
    610                 615                 620                 


Met Asp Ala Lys Thr Val Thr Ala Ser Ile Lys Pro Lys Cys Gly Arg 
625                 630                 635                 640 


Met Ile Ser Phe Ser Ser Gly Gly Glu Asn Pro His Gly Val Lys Ala 
                645                 650                 655     


Val Thr Lys Gly Lys Arg Cys Ala Val Ala Leu Trp Phe Thr Leu Asp 
            660                 665                 670         


Pro Leu Tyr Arg Glu Leu Glu Arg Ile Gln Ala Asp Glu Val Ile Ala 
        675                 680                 685             


Ile Leu Asp Gln Glu Gln Gln Gly Lys His Glu Leu Asn Ile Asn Pro 
    690                 695                 700                 


Lys Asp Glu Leu 
705             


<210>  2752
<211>  527
<212>  PRT
<213>  homo sapiens

<400>  2752

Met Glu Met Gln Gln Asn Ile Glu Asn Tyr Arg Ala Thr Ala Gly Val 
1               5                   10                  15      


Glu Ala Leu Gln Leu Val Asp Arg Glu Ala Lys Pro His Met Glu Ser 
            20                  25                  30          


Tyr Asn Ala Gly Val Lys His Tyr Glu Ala Asp Asp Phe Glu Met Ala 
        35                  40                  45              


Ile Arg His Phe Glu Gln Ala Leu Arg Glu Tyr Phe Val Glu Asp Thr 
    50                  55                  60                  


Glu Cys Arg Thr Leu Cys Glu Gly Pro Gln Arg Phe Glu Glu Tyr Glu 
65                  70                  75                  80  


Tyr Leu Gly Tyr Lys Ala Gly Leu Tyr Glu Ala Ile Ala Asp His Tyr 
                85                  90                  95      


Met Gln Val Leu Val Cys Gln His Glu Cys Val Arg Glu Leu Ala Thr 
            100                 105                 110         


Arg Pro Gly Arg Leu Ser Pro Ile Glu Asn Phe Leu Pro Leu His Tyr 
        115                 120                 125             


Asp Tyr Leu Gln Phe Ala Tyr Tyr Arg Val Gly Glu Tyr Val Lys Ala 
    130                 135                 140                 


Leu Glu Cys Ala Lys Ala Tyr Leu Leu Cys His Pro Asp Asp Glu Asp 
145                 150                 155                 160 


Val Leu Asp Asn Val Asp Tyr Tyr Glu Ser Leu Leu Asp Asp Ser Ile 
                165                 170                 175     


Asp Pro Ala Ser Ile Glu Ala Arg Glu Asp Leu Thr Met Phe Val Lys 
            180                 185                 190         


Arg His Lys Leu Glu Ser Glu Leu Ile Lys Ser Ala Ala Glu Gly Leu 
        195                 200                 205             


Gly Phe Ser Tyr Thr Glu Pro Asn Tyr Trp Ile Arg Tyr Gly Gly Arg 
    210                 215                 220                 


Gln Asp Glu Asn Arg Val Pro Ser Gly Val Asn Val Glu Gly Ala Glu 
225                 230                 235                 240 


Val His Gly Phe Ser Met Gly Lys Lys Leu Ser Pro Lys Ile Asp Arg 
                245                 250                 255     


Asp Leu Arg Glu Gly Gly Pro Leu Leu Tyr Glu Asn Ile Thr Phe Val 
            260                 265                 270         


Tyr Asn Ser Glu Gln Leu Asn Gly Thr Gln Arg Val Leu Leu Asp Asn 
        275                 280                 285             


Val Leu Ser Glu Glu Gln Cys Arg Glu Leu His Ser Val Ala Ser Gly 
    290                 295                 300                 


Ile Met Leu Val Gly Asp Gly Tyr Arg Gly Lys Thr Ser Pro His Thr 
305                 310                 315                 320 


Pro Asn Glu Lys Phe Glu Gly Ala Thr Val Leu Lys Ala Leu Lys Ser 
                325                 330                 335     


Gly Tyr Glu Gly Arg Val Pro Leu Lys Ser Ala Arg Leu Phe Tyr Asp 
            340                 345                 350         


Ile Ser Glu Lys Ala Arg Arg Ile Val Glu Ser Tyr Phe Met Leu Asn 
        355                 360                 365             


Ser Thr Leu Tyr Phe Ser Tyr Thr His Met Val Cys Arg Thr Ala Leu 
    370                 375                 380                 


Ser Gly Gln Gln Asp Arg Arg Asn Asp Leu Ser His Pro Ile His Ala 
385                 390                 395                 400 


Asp Asn Cys Leu Leu Asp Pro Glu Ala Asn Glu Cys Trp Lys Glu Pro 
                405                 410                 415     


Pro Ala Tyr Thr Phe Arg Asp Tyr Ser Ala Leu Leu Tyr Met Asn Asp 
            420                 425                 430         


Asp Phe Glu Gly Gly Glu Phe Ile Phe Thr Glu Met Asp Ala Lys Thr 
        435                 440                 445             


Val Thr Ala Ser Ile Lys Pro Lys Cys Gly Arg Met Ile Ser Phe Ser 
    450                 455                 460                 


Ser Gly Gly Glu Asn Pro His Gly Val Lys Ala Val Thr Lys Gly Lys 
465                 470                 475                 480 


Arg Cys Ala Val Ala Leu Trp Phe Thr Leu Asp Pro Leu Tyr Arg Glu 
                485                 490                 495     


Leu Glu Arg Ile Gln Ala Asp Glu Val Ile Ala Ile Leu Asp Gln Glu 
            500                 505                 510         


Gln Gln Gly Lys His Glu Leu Asn Ile Asn Pro Lys Asp Glu Leu 
        515                 520                 525         


<210>  2753
<211>  870
<212>  PRT
<213>  homo sapiens

<400>  2753

Met Asn Ser Asn Leu Pro Ala Glu Asn Leu Thr Ile Ala Val Asn Met 
1               5                   10                  15      


Thr Lys Thr Leu Pro Thr Ala Val Thr His Gly Phe Asn Ser Thr Asn 
            20                  25                  30          


Asp Pro Pro Ser Met Ser Ile Thr Arg Leu Phe Pro Ala Leu Leu Glu 
        35                  40                  45              


Cys Phe Gly Ile Val Leu Cys Gly Tyr Ile Ala Gly Arg Ala Asn Val 
    50                  55                  60                  


Ile Thr Ser Thr Gln Ala Lys Gly Leu Gly Asn Phe Val Ser Arg Phe 
65                  70                  75                  80  


Ala Leu Pro Ala Leu Leu Phe Lys Asn Met Val Val Leu Asn Phe Ser 
                85                  90                  95      


Asn Val Asp Trp Ser Phe Leu Tyr Ser Ile Leu Ile Ala Lys Ala Ser 
            100                 105                 110         


Val Phe Phe Ile Val Cys Val Leu Thr Leu Leu Val Ala Ser Pro Asp 
        115                 120                 125             


Ser Arg Phe Ser Lys Ala Gly Leu Phe Pro Ile Phe Ala Thr Gln Ser 
    130                 135                 140                 


Asn Asp Phe Ala Leu Gly Tyr Pro Ile Val Glu Ala Leu Tyr Gln Thr 
145                 150                 155                 160 


Thr Tyr Pro Glu Tyr Leu Gln Tyr Ile Tyr Leu Val Ala Pro Ile Ser 
                165                 170                 175     


Leu Met Met Leu Asn Pro Ile Gly Phe Ile Phe Cys Glu Ile Gln Lys 
            180                 185                 190         


Trp Lys Asp Thr Gln Asn Ala Ser Gln Asn Lys Ile Lys Ile Val Gly 
        195                 200                 205             


Leu Gly Leu Leu Arg Val Leu Gln Asn Pro Ile Val Phe Met Val Phe 
    210                 215                 220                 


Ile Gly Ile Ala Phe Asn Phe Ile Leu Asp Arg Lys Val Pro Val Tyr 
225                 230                 235                 240 


Val Glu Asn Phe Leu Asp Gly Leu Gly Asn Ser Phe Ser Gly Ser Ala 
                245                 250                 255     


Leu Phe Tyr Leu Gly Leu Thr Met Val Gly Lys Ile Lys Arg Leu Lys 
            260                 265                 270         


Lys Ser Ala Phe Val Val Leu Ile Leu Leu Ile Thr Ala Lys Leu Leu 
        275                 280                 285             


Val Leu Pro Leu Leu Cys Arg Glu Met Val Glu Leu Leu Asp Lys Gly 
    290                 295                 300                 


Asp Ser Val Val Asn His Thr Ser Leu Ser Asn Tyr Ala Phe Leu Tyr 
305                 310                 315                 320 


Gly Val Phe Pro Val Ala Pro Gly Val Ala Ile Phe Ala Thr Gln Phe 
                325                 330                 335     


Asn Met Glu Val Glu Ile Ile Thr Ser Gly Met Val Ile Ser Thr Phe 
            340                 345                 350         


Val Ser Ala Pro Ile Met Tyr Val Ser Ala Trp Leu Leu Thr Phe Pro 
        355                 360                 365             


Thr Met Asp Pro Lys Pro Leu Ala Tyr Ala Ile Gln Asn Val Ser Phe 
    370                 375                 380                 


Asp Ile Ser Ile Val Ser Leu Ile Ser Leu Ile Trp Ser Leu Ala Ile 
385                 390                 395                 400 


Leu Leu Leu Ser Lys Lys Tyr Lys Gln Leu Pro His Met Leu Thr Thr 
                405                 410                 415     


Asn Leu Leu Ile Ala Gln Ser Ile Val Cys Ala Gly Met Met Ile Trp 
            420                 425                 430         


Asn Phe Val Lys Glu Lys Asn Phe Val Gly Gln Ile Leu Val Phe Val 
        435                 440                 445             


Leu Leu Tyr Ser Ser Leu Tyr Ser Thr Tyr Leu Trp Thr Gly Leu Leu 
    450                 455                 460                 


Ala Ile Ser Leu Phe Leu Leu Lys Lys Arg Glu Arg Val Gln Ile Pro 
465                 470                 475                 480 


Val Gly Ile Ile Ile Ile Ser Gly Trp Gly Ile Pro Ala Leu Leu Val 
                485                 490                 495     


Gly Val Leu Leu Ile Thr Gly Lys His Asn Gly Asp Ser Ile Asp Ser 
            500                 505                 510         


Ala Phe Phe Tyr Gly Lys Glu Gln Met Ile Thr Thr Ala Val Thr Leu 
        515                 520                 525             


Phe Cys Ser Ile Leu Ile Ala Gly Ile Ser Leu Met Cys Met Asn Gln 
    530                 535                 540                 


Thr Ala Gln Ala Gly Ser Tyr Glu Gly Phe Asp Gln Ser Gln Ser His 
545                 550                 555                 560 


Lys Val Val Glu Pro Gly Asn Thr Ala Phe Glu Glu Ser Pro Ala Pro 
                565                 570                 575     


Val Asn Glu Pro Glu Leu Phe Thr Ser Ser Ile Pro Glu Thr Ser Cys 
            580                 585                 590         


Cys Ser Cys Ser Met Gly Asn Gly Glu Leu His Cys Pro Ser Ile Glu 
        595                 600                 605             


Pro Ile Ala Asn Thr Ser Thr Ser Glu Pro Val Ile Pro Ser Phe Glu 
    610                 615                 620                 


Lys Asn Asn His Cys Val Ser Arg Cys Asn Ser Gln Ser Cys Ile Leu 
625                 630                 635                 640 


Ala Gln Glu Glu Glu Gln Tyr Leu Gln Ser Gly Asp Gln Gln Leu Thr 
                645                 650                 655     


Arg His Val Leu Leu Cys Leu Leu Leu Ile Ile Gly Leu Phe Ala Asn 
            660                 665                 670         


Leu Ser Ser Cys Leu Trp Trp Leu Phe Asn Gln Glu Pro Gly Arg Leu 
        675                 680                 685             


Tyr Val Glu Leu Gln Phe Phe Cys Ala Val Phe Asn Phe Gly Gln Gly 
    690                 695                 700                 


Phe Ile Ser Phe Gly Ile Phe Gly Leu Asp Lys His Leu Ile Ile Leu 
705                 710                 715                 720 


Pro Phe Lys Arg Arg Leu Glu Phe Leu Trp Asn Asn Lys Asp Thr Ala 
                725                 730                 735     


Glu Asn Arg Asp Ser Pro Val Ser Glu Glu Ile Lys Met Thr Cys Gln 
            740                 745                 750         


Gln Phe Ile His Tyr His Arg Asp Leu Cys Ile Arg Asn Ile Val Lys 
        755                 760                 765             


Glu Arg Arg Cys Gly Ala Lys Thr Ser Ala Gly Thr Phe Cys Gly Cys 
    770                 775                 780                 


Asp Leu Val Ser Trp Leu Ile Glu Val Gly Leu Ala Ser Asp Arg Gly 
785                 790                 795                 800 


Glu Ala Val Ile Tyr Gly Asp Arg Leu Val Gln Gly Gly Val Ile Gln 
                805                 810                 815     


His Ile Thr Asn Glu Tyr Glu Phe Arg Asp Glu Tyr Leu Phe Tyr Arg 
            820                 825                 830         


Phe Leu Gln Lys Ser Pro Glu Gln Ser Pro Pro Ala Ile Asn Ala Asn 
        835                 840                 845             


Thr Leu Gln Gln Glu Arg Tyr Lys Glu Ile Glu His Ser Ser Pro Pro 
    850                 855                 860                 


Ser His Ser Pro Lys Thr 
865                 870 


<210>  2754
<211>  727
<212>  PRT
<213>  homo sapiens

<400>  2754

Met Val Ser Phe Arg Leu Ser Asn Lys Thr Ala Ser Pro Ser Ile Lys 
1               5                   10                  15      


Leu Leu Val Asp Asp Pro Ile Val Val Asn Pro Gly Glu Ala Ile Thr 
            20                  25                  30          


Leu Val Cys Val Thr Thr Gly Gly Glu Pro Ala Pro Ser Leu Thr Trp 
        35                  40                  45              


Val Arg Ser Phe Gly Thr Leu Pro Glu Lys Thr Val Leu Asn Gly Gly 
    50                  55                  60                  


Thr Leu Thr Ile Pro Ala Ile Thr Ser Asp Asp Ala Gly Thr Tyr Ser 
65                  70                  75                  80  


Cys Ile Ala Asn Asn Asn Val Gly Asn Pro Ala Lys Lys Ser Thr Asn 
                85                  90                  95      


Ile Ile Val Arg Ala Leu Lys Lys Gly Arg Phe Trp Ile Thr Pro Asp 
            100                 105                 110         


Pro Tyr His Lys Asp Asp Asn Ile Gln Ile Gly Arg Glu Val Lys Ile 
        115                 120                 125             


Ser Cys Gln Val Glu Ala Val Pro Ser Glu Glu Leu Thr Phe Ser Trp 
    130                 135                 140                 


Phe Lys Asn Gly Arg Pro Leu Arg Ser Ser Glu Arg Met Val Ile Thr 
145                 150                 155                 160 


Gln Thr Asp Pro Asp Val Ser Pro Gly Thr Thr Asn Leu Asp Ile Ile 
                165                 170                 175     


Asp Leu Lys Phe Thr Asp Phe Gly Thr Tyr Thr Cys Val Ala Ser Leu 
            180                 185                 190         


Lys Gly Gly Gly Ile Ser Asp Ile Ser Ile Asp Val Asn Ile Ser Ser 
        195                 200                 205             


Ser Thr Val Pro Pro Asn Leu Thr Val Pro Gln Glu Lys Ser Pro Leu 
    210                 215                 220                 


Val Thr Arg Glu Gly Asp Thr Ile Glu Leu Gln Cys Gln Val Thr Gly 
225                 230                 235                 240 


Lys Pro Lys Pro Ile Ile Leu Trp Ser Arg Ala Asp Lys Glu Val Ala 
                245                 250                 255     


Met Pro Asp Gly Ser Met Gln Met Glu Ser Tyr Asp Gly Thr Leu Arg 
            260                 265                 270         


Ile Val Asn Val Ser Arg Glu Met Ser Gly Met Tyr Arg Cys Gln Thr 
        275                 280                 285             


Ser Gln Tyr Asn Gly Phe Asn Val Lys Pro Arg Glu Ala Leu Val Gln 
    290                 295                 300                 


Leu Ile Val Gln Tyr Pro Pro Ala Val Glu Pro Ala Phe Leu Glu Ile 
305                 310                 315                 320 


Arg Gln Gly Gln Asp Arg Ser Val Thr Met Ser Cys Arg Val Leu Arg 
                325                 330                 335     


Ala Tyr Pro Ile Arg Val Leu Thr Tyr Glu Trp Arg Leu Gly Asn Lys 
            340                 345                 350         


Leu Leu Arg Thr Gly Gln Phe Asp Ser Gln Glu Tyr Thr Glu Tyr Ala 
        355                 360                 365             


Val Lys Ser Leu Ser Asn Glu Asn Tyr Gly Val Tyr Asn Cys Ser Ile 
    370                 375                 380                 


Ile Asn Glu Ala Gly Ala Gly Arg Cys Ser Phe Leu Val Thr Gly Lys 
385                 390                 395                 400 


Ala Tyr Ala Pro Glu Phe Tyr Tyr Asp Thr Tyr Asn Pro Val Trp Gln 
                405                 410                 415     


Asn Arg His Arg Val Tyr Ser Tyr Ser Leu Gln Trp Thr Gln Met Asn 
            420                 425                 430         


Pro Asp Ala Val Asp Arg Ile Val Ala Tyr Arg Leu Gly Ile Arg Gln 
        435                 440                 445             


Ala Gly Gln Gln Arg Trp Trp Glu Gln Glu Ile Lys Ile Asn Gly Asn 
    450                 455                 460                 


Ile Gln Lys Gly Glu Leu Ile Thr Tyr Asn Leu Thr Glu Leu Ile Lys 
465                 470                 475                 480 


Pro Glu Ala Tyr Glu Val Arg Leu Thr Pro Leu Thr Lys Phe Gly Glu 
                485                 490                 495     


Gly Asp Ser Thr Ile Arg Val Ile Lys Tyr Ser Ala Pro Val Asn Pro 
            500                 505                 510         


His Leu Arg Glu Phe His Cys Gly Phe Glu Asp Gly Asn Ile Cys Leu 
        515                 520                 525             


Phe Thr Gln Asp Asp Thr Asp Asn Phe Asp Trp Thr Lys Gln Ser Thr 
    530                 535                 540                 


Ala Thr Arg Asn Thr Lys Tyr Thr Pro Asn Thr Gly Pro Asn Ala Asp 
545                 550                 555                 560 


Arg Ser Gly Ser Lys Glu Gly Phe Tyr Met Tyr Ile Glu Thr Ser Arg 
                565                 570                 575     


Pro Arg Leu Glu Gly Glu Lys Ala Arg Leu Leu Ser Pro Val Phe Ser 
            580                 585                 590         


Ile Ala Pro Lys Asn Pro Tyr Gly Pro Thr Asn Thr Ala Tyr Cys Phe 
        595                 600                 605             


Ser Phe Phe Tyr His Met Tyr Gly Gln His Ile Gly Val Leu Asn Val 
    610                 615                 620                 


Tyr Leu Arg Leu Lys Gly Gln Thr Thr Ile Glu Asn Pro Leu Trp Ser 
625                 630                 635                 640 


Ser Ser Gly Asn Lys Gly Gln Arg Trp Asn Glu Ala His Val Asn Ile 
                645                 650                 655     


Tyr Pro Ile Thr Ser Phe Gln Leu Ile Phe Glu Gly Ile Arg Gly Pro 
            660                 665                 670         


Gly Ile Glu Gly Asp Ile Ala Ile Asp Asp Val Ser Ile Ala Glu Gly 
        675                 680                 685             


Glu Cys Ala Lys Gln Asp Leu Ala Thr Lys Asn Ser Val Asp Gly Ala 
    690                 695                 700                 


Val Gly Ile Leu Val His Ile Trp Leu Phe Pro Ile Ile Val Leu Ile 
705                 710                 715                 720 


Ser Ile Leu Ser Pro Arg Arg 
                725         


<210>  2755
<211>  1806
<212>  PRT
<213>  homo sapiens

<400>  2755

Met Glu Pro Trp Ser Ser Arg Trp Lys Thr Lys Arg Trp Leu Trp Asp 
1               5                   10                  15      


Phe Thr Val Thr Thr Leu Ala Leu Thr Phe Leu Phe Gln Ala Arg Glu 
            20                  25                  30          


Val Arg Gly Ala Ala Pro Val Asp Val Leu Lys Ala Leu Asp Phe His 
        35                  40                  45              


Asn Ser Pro Glu Gly Ile Ser Lys Thr Thr Gly Phe Cys Thr Asn Arg 
    50                  55                  60                  


Lys Asn Ser Lys Gly Ser Asp Thr Ala Tyr Arg Val Ser Lys Gln Ala 
65                  70                  75                  80  


Gln Leu Ser Ala Pro Thr Lys Gln Leu Phe Pro Gly Gly Thr Phe Pro 
                85                  90                  95      


Glu Asp Phe Ser Ile Leu Phe Thr Val Lys Pro Lys Lys Gly Ile Gln 
            100                 105                 110         


Ser Phe Leu Leu Ser Ile Tyr Asn Glu His Gly Ile Gln Gln Ile Gly 
        115                 120                 125             


Val Glu Val Gly Arg Ser Pro Val Phe Leu Phe Glu Asp His Thr Gly 
    130                 135                 140                 


Lys Pro Ala Pro Glu Asp Tyr Pro Leu Phe Arg Thr Val Asn Ile Ala 
145                 150                 155                 160 


Asp Gly Lys Trp His Arg Val Ala Ile Ser Val Glu Lys Lys Thr Val 
                165                 170                 175     


Thr Met Ile Val Asp Cys Lys Lys Lys Thr Thr Lys Pro Leu Asp Arg 
            180                 185                 190         


Ser Glu Arg Ala Ile Val Asp Thr Asn Gly Ile Thr Val Phe Gly Thr 
        195                 200                 205             


Arg Ile Leu Asp Glu Glu Val Phe Glu Gly Asp Ile Gln Gln Phe Leu 
    210                 215                 220                 


Ile Thr Gly Asp Pro Lys Ala Ala Tyr Asp Tyr Cys Glu His Tyr Ser 
225                 230                 235                 240 


Pro Asp Cys Asp Ser Ser Ala Pro Lys Ala Ala Gln Ala Gln Glu Pro 
                245                 250                 255     


Gln Ile Asp Glu Tyr Ala Pro Glu Asp Ile Ile Glu Tyr Asp Tyr Glu 
            260                 265                 270         


Tyr Gly Glu Ala Glu Tyr Lys Glu Ala Glu Ser Val Thr Glu Gly Pro 
        275                 280                 285             


Thr Val Thr Glu Glu Thr Ile Ala Gln Thr Glu Ala Asn Ile Val Asp 
    290                 295                 300                 


Asp Phe Gln Glu Tyr Asn Tyr Gly Thr Met Glu Ser Tyr Gln Thr Glu 
305                 310                 315                 320 


Ala Pro Arg His Val Ser Gly Thr Asn Glu Pro Asn Pro Val Glu Glu 
                325                 330                 335     


Ile Phe Thr Glu Glu Tyr Leu Thr Gly Glu Asp Tyr Asp Ser Gln Arg 
            340                 345                 350         


Lys Asn Ser Glu Asp Thr Leu Tyr Glu Asn Lys Glu Ile Asp Gly Arg 
        355                 360                 365             


Asp Ser Asp Leu Leu Val Asp Gly Asp Leu Gly Glu Tyr Asp Phe Tyr 
    370                 375                 380                 


Glu Tyr Lys Glu Tyr Glu Asp Lys Pro Thr Ser Pro Pro Asn Glu Glu 
385                 390                 395                 400 


Phe Gly Pro Gly Val Pro Ala Glu Thr Asp Ile Thr Glu Thr Ser Ile 
                405                 410                 415     


Asn Gly His Gly Ala Tyr Gly Glu Lys Gly Gln Lys Gly Glu Pro Ala 
            420                 425                 430         


Val Val Glu Pro Gly Met Leu Val Glu Gly Pro Pro Gly Pro Ala Gly 
        435                 440                 445             


Pro Ala Gly Ile Met Gly Pro Pro Gly Leu Gln Gly Pro Thr Gly Pro 
    450                 455                 460                 


Pro Gly Asp Pro Gly Asp Arg Gly Pro Pro Gly Arg Pro Gly Leu Pro 
465                 470                 475                 480 


Gly Ala Asp Gly Leu Pro Gly Pro Pro Gly Thr Met Leu Met Leu Pro 
                485                 490                 495     


Phe Arg Tyr Gly Gly Asp Gly Ser Lys Gly Pro Thr Ile Ser Ala Gln 
            500                 505                 510         


Glu Ala Gln Ala Gln Ala Ile Leu Gln Gln Ala Arg Ile Ala Leu Arg 
        515                 520                 525             


Gly Pro Pro Gly Pro Met Gly Leu Thr Gly Arg Pro Gly Pro Val Gly 
    530                 535                 540                 


Gly Pro Gly Ser Ser Gly Ala Lys Gly Glu Ser Gly Asp Pro Gly Pro 
545                 550                 555                 560 


Gln Gly Pro Arg Gly Val Gln Gly Pro Pro Gly Pro Thr Gly Lys Pro 
                565                 570                 575     


Gly Lys Arg Gly Arg Pro Gly Ala Asp Gly Gly Arg Gly Met Pro Gly 
            580                 585                 590         


Glu Pro Gly Ala Lys Gly Asp Arg Gly Phe Asp Gly Leu Pro Gly Leu 
        595                 600                 605             


Pro Gly Asp Lys Gly His Arg Gly Glu Arg Gly Pro Gln Gly Pro Pro 
    610                 615                 620                 


Gly Pro Pro Gly Asp Asp Gly Met Arg Gly Glu Asp Gly Glu Ile Gly 
625                 630                 635                 640 


Pro Arg Gly Leu Pro Gly Glu Ala Gly Pro Arg Gly Leu Leu Gly Pro 
                645                 650                 655     


Arg Gly Thr Pro Gly Ala Pro Gly Gln Pro Gly Met Ala Gly Val Asp 
            660                 665                 670         


Gly Pro Pro Gly Pro Lys Gly Asn Met Gly Pro Gln Gly Glu Pro Gly 
        675                 680                 685             


Pro Pro Gly Gln Gln Gly Asn Pro Gly Pro Gln Gly Leu Pro Gly Pro 
    690                 695                 700                 


Gln Gly Pro Ile Gly Pro Pro Gly Glu Lys Gly Pro Gln Gly Lys Pro 
705                 710                 715                 720 


Gly Leu Ala Gly Leu Pro Gly Ala Asp Gly Pro Pro Gly His Pro Gly 
                725                 730                 735     


Lys Glu Gly Gln Ser Gly Glu Lys Gly Ala Leu Gly Pro Pro Gly Pro 
            740                 745                 750         


Gln Gly Pro Ile Gly Tyr Pro Gly Pro Arg Gly Val Lys Gly Ala Asp 
        755                 760                 765             


Gly Val Arg Gly Leu Lys Gly Ser Lys Gly Glu Lys Gly Glu Asp Gly 
    770                 775                 780                 


Phe Pro Gly Phe Lys Gly Asp Met Gly Leu Lys Gly Asp Arg Gly Glu 
785                 790                 795                 800 


Val Gly Gln Ile Gly Pro Arg Gly Glu Asp Gly Pro Glu Gly Pro Lys 
                805                 810                 815     


Gly Arg Ala Gly Pro Thr Gly Asp Pro Gly Pro Ser Gly Gln Ala Gly 
            820                 825                 830         


Glu Lys Gly Lys Leu Gly Val Pro Gly Leu Pro Gly Tyr Pro Gly Arg 
        835                 840                 845             


Gln Gly Pro Lys Gly Ser Thr Gly Phe Pro Gly Phe Pro Gly Ala Asn 
    850                 855                 860                 


Gly Glu Lys Gly Ala Arg Gly Val Ala Gly Lys Pro Gly Pro Arg Gly 
865                 870                 875                 880 


Gln Arg Gly Pro Thr Gly Pro Arg Gly Ser Arg Gly Ala Arg Gly Pro 
                885                 890                 895     


Thr Gly Lys Pro Gly Pro Lys Gly Thr Ser Gly Gly Asp Gly Pro Pro 
            900                 905                 910         


Gly Pro Pro Gly Glu Arg Gly Pro Gln Gly Pro Gln Gly Pro Val Gly 
        915                 920                 925             


Phe Pro Gly Pro Lys Gly Pro Pro Gly Pro Pro Gly Lys Asp Gly Leu 
    930                 935                 940                 


Pro Gly His Pro Gly Gln Arg Gly Glu Thr Gly Phe Gln Gly Lys Thr 
945                 950                 955                 960 


Gly Pro Pro Gly Pro Gly Gly Val Val Gly Pro Gln Gly Pro Thr Gly 
                965                 970                 975     


Glu Thr Gly Pro Ile Gly Glu Arg Gly His Pro Gly Pro Pro Gly Pro 
            980                 985                 990         


Pro Gly Glu Gln Gly Leu Pro Gly  Ala Ala Gly Lys Glu  Gly Ala Lys 
        995                 1000                 1005             


Gly Asp  Pro Gly Pro Gln Gly  Ile Ser Gly Lys Asp  Gly Pro Ala 
    1010                 1015                 1020             


Gly Leu  Arg Gly Phe Pro Gly  Glu Arg Gly Leu Pro  Gly Ala Gln 
    1025                 1030                 1035             


Gly Ala  Pro Gly Leu Lys Gly  Gly Glu Gly Pro Gln  Gly Pro Pro 
    1040                 1045                 1050             


Gly Pro  Val Gly Ser Pro Gly  Glu Arg Gly Ser Ala  Gly Thr Ala 
    1055                 1060                 1065             


Gly Pro  Ile Gly Leu Pro Gly  Arg Pro Gly Pro Gln  Gly Pro Pro 
    1070                 1075                 1080             


Gly Pro  Ala Gly Glu Lys Gly  Ala Pro Gly Glu Lys  Gly Pro Gln 
    1085                 1090                 1095             


Gly Pro  Ala Gly Arg Asp Gly  Val Gln Gly Pro Val  Gly Leu Pro 
    1100                 1105                 1110             


Gly Pro  Ala Gly Pro Ala Gly  Ser Pro Gly Glu Asp  Gly Asp Lys 
    1115                 1120                 1125             


Gly Glu  Ile Gly Glu Pro Gly  Gln Lys Gly Ser Lys  Gly Asp Lys 
    1130                 1135                 1140             


Gly Glu  Asn Gly Pro Pro Gly  Pro Pro Gly Leu Gln  Gly Pro Val 
    1145                 1150                 1155             


Gly Ala  Pro Gly Ile Ala Gly  Gly Asp Gly Glu Pro  Gly Pro Arg 
    1160                 1165                 1170             


Gly Gln  Gln Gly Met Phe Gly  Gln Lys Gly Asp Glu  Gly Ala Arg 
    1175                 1180                 1185             


Gly Phe  Pro Gly Pro Pro Gly  Pro Ile Gly Leu Gln  Gly Leu Pro 
    1190                 1195                 1200             


Gly Pro  Pro Gly Glu Lys Gly  Glu Asn Gly Asp Val  Gly Pro Met 
    1205                 1210                 1215             


Gly Pro  Pro Gly Pro Pro Gly  Pro Arg Gly Pro Gln  Gly Pro Asn 
    1220                 1225                 1230             


Gly Ala  Asp Gly Pro Gln Gly  Pro Pro Gly Ser Val  Gly Ser Val 
    1235                 1240                 1245             


Gly Gly  Val Gly Glu Lys Gly  Glu Pro Gly Glu Ala  Gly Asn Pro 
    1250                 1255                 1260             


Gly Pro  Pro Gly Glu Ala Gly  Val Gly Gly Pro Lys  Gly Glu Arg 
    1265                 1270                 1275             


Gly Glu  Lys Gly Glu Ala Gly  Pro Pro Gly Ala Ala  Gly Pro Pro 
    1280                 1285                 1290             


Gly Ala  Lys Gly Pro Pro Gly  Asp Asp Gly Pro Lys  Gly Asn Pro 
    1295                 1300                 1305             


Gly Pro  Val Gly Phe Pro Gly  Asp Pro Gly Pro Pro  Gly Glu Pro 
    1310                 1315                 1320             


Gly Pro  Ala Gly Gln Asp Gly  Val Gly Gly Asp Lys  Gly Glu Asp 
    1325                 1330                 1335             


Gly Asp  Pro Gly Gln Pro Gly  Pro Pro Gly Pro Ser  Gly Glu Ala 
    1340                 1345                 1350             


Gly Pro  Pro Gly Pro Pro Gly  Lys Arg Gly Pro Pro  Gly Ala Ala 
    1355                 1360                 1365             


Gly Ala  Glu Gly Arg Gln Gly  Glu Lys Gly Ala Lys  Gly Glu Ala 
    1370                 1375                 1380             


Gly Ala  Glu Gly Pro Pro Gly  Lys Thr Gly Pro Val  Gly Pro Gln 
    1385                 1390                 1395             


Gly Pro  Ala Gly Lys Pro Gly  Pro Glu Gly Leu Arg  Gly Ile Pro 
    1400                 1405                 1410             


Gly Pro  Val Gly Glu Gln Gly  Leu Pro Gly Ala Ala  Gly Gln Asp 
    1415                 1420                 1425             


Gly Pro  Pro Gly Pro Met Gly  Pro Pro Gly Leu Pro  Gly Leu Lys 
    1430                 1435                 1440             


Gly Asp  Pro Gly Ser Lys Gly  Glu Lys Gly His Pro  Gly Leu Ile 
    1445                 1450                 1455             


Gly Leu  Ile Gly Pro Pro Gly  Glu Gln Gly Glu Lys  Gly Asp Arg 
    1460                 1465                 1470             


Gly Leu  Pro Gly Thr Gln Gly  Ser Pro Gly Ala Lys  Gly Asp Gly 
    1475                 1480                 1485             


Gly Ile  Pro Gly Pro Ala Gly  Pro Leu Gly Pro Pro  Gly Pro Pro 
    1490                 1495                 1500             


Gly Leu  Pro Gly Pro Gln Gly  Pro Lys Gly Asn Lys  Gly Ser Thr 
    1505                 1510                 1515             


Gly Pro  Ala Gly Gln Lys Gly  Asp Ser Gly Leu Pro  Gly Pro Pro 
    1520                 1525                 1530             


Gly Ser  Pro Gly Pro Pro Gly  Glu Val Ile Gln Pro  Leu Pro Ile 
    1535                 1540                 1545             


Leu Ser  Ser Lys Lys Thr Arg  Arg His Thr Glu Gly  Met Gln Ala 
    1550                 1555                 1560             


Asp Ala  Asp Asp Asn Ile Leu  Asp Tyr Ser Asp Gly  Met Glu Glu 
    1565                 1570                 1575             


Ile Phe  Gly Ser Leu Asn Ser  Leu Lys Gln Asp Ile  Glu His Met 
    1580                 1585                 1590             


Lys Phe  Pro Met Gly Thr Gln  Thr Asn Pro Ala Arg  Thr Cys Lys 
    1595                 1600                 1605             


Asp Leu  Gln Leu Ser His Pro  Asp Phe Pro Asp Gly  Glu Tyr Trp 
    1610                 1615                 1620             


Ile Asp  Pro Asn Gln Gly Cys  Ser Gly Asp Ser Phe  Lys Val Tyr 
    1625                 1630                 1635             


Cys Asn  Phe Thr Ser Gly Gly  Glu Thr Cys Ile Tyr  Pro Asp Lys 
    1640                 1645                 1650             


Lys Ser  Glu Gly Val Arg Ile  Ser Ser Trp Pro Lys  Glu Lys Pro 
    1655                 1660                 1665             


Gly Ser  Trp Phe Ser Glu Phe  Lys Arg Gly Lys Leu  Leu Ser Tyr 
    1670                 1675                 1680             


Leu Asp  Val Glu Gly Asn Ser  Ile Asn Met Val Gln  Met Thr Phe 
    1685                 1690                 1695             


Leu Lys  Leu Leu Thr Ala Ser  Ala Arg Gln Asn Phe  Thr Tyr His 
    1700                 1705                 1710             


Cys His  Gln Ser Ala Ala Trp  Tyr Asp Val Ser Ser  Gly Ser Tyr 
    1715                 1720                 1725             


Asp Lys  Ala Leu Arg Phe Leu  Gly Ser Asn Asp Glu  Glu Met Ser 
    1730                 1735                 1740             


Tyr Asp  Asn Asn Pro Phe Ile  Lys Thr Leu Tyr Asp  Gly Cys Ala 
    1745                 1750                 1755             


Ser Arg  Lys Gly Tyr Glu Lys  Thr Val Ile Glu Ile  Asn Thr Pro 
    1760                 1765                 1770             


Lys Ile  Asp Gln Val Pro Ile  Val Asp Val Met Ile  Asn Asp Phe 
    1775                 1780                 1785             


Gly Asp  Gln Asn Gln Lys Phe  Gly Phe Glu Val Gly  Pro Val Cys 
    1790                 1795                 1800             


Phe Leu  Gly 
    1805     


<210>  2756
<211>  986
<212>  PRT
<213>  homo sapiens

<400>  2756

Met Gly Pro Pro Leu Pro Leu Leu Leu Leu Leu Leu Leu Leu Leu Pro 
1               5                   10                  15      


Pro Arg Val Leu Pro Ala Ala Pro Ser Ser Val Pro Arg Gly Arg Gln 
            20                  25                  30          


Leu Pro Gly Arg Leu Gly Cys Leu Leu Glu Glu Gly Leu Cys Gly Ala 
        35                  40                  45              


Ser Glu Ala Cys Val Asn Asp Gly Val Phe Gly Arg Cys Gln Lys Val 
    50                  55                  60                  


Pro Ala Met Asp Phe Tyr Arg Tyr Glu Val Ser Pro Val Ala Leu Gln 
65                  70                  75                  80  


Arg Leu Arg Val Ala Leu Gln Lys Leu Ser Gly Thr Gly Phe Thr Trp 
                85                  90                  95      


Gln Asp Asp Tyr Thr Gln Tyr Val Met Asp Gln Glu Leu Ala Asp Leu 
            100                 105                 110         


Pro Lys Thr Tyr Leu Arg Arg Pro Glu Ala Ser Ser Pro Ala Arg Pro 
        115                 120                 125             


Ser Lys His Ser Val Gly Ser Glu Arg Arg Tyr Ser Arg Glu Gly Gly 
    130                 135                 140                 


Ala Ala Leu Ala Asn Ala Leu Arg Arg His Leu Pro Phe Leu Glu Ala 
145                 150                 155                 160 


Leu Ser Gln Ala Pro Ala Ser Asp Val Leu Ala Arg Thr His Thr Ala 
                165                 170                 175     


Gln Asp Arg Pro Pro Ala Glu Gly Asp Asp Arg Phe Ser Glu Ser Ile 
            180                 185                 190         


Leu Thr Tyr Val Ala His Thr Ser Ala Leu Thr Tyr Pro Pro Gly Ser 
        195                 200                 205             


Arg Thr Gln Leu Arg Glu Asp Leu Leu Pro Arg Thr Leu Gly Gln Leu 
    210                 215                 220                 


Gln Pro Asp Glu Leu Ser Pro Lys Val Asp Ser Gly Val Asp Arg His 
225                 230                 235                 240 


His Leu Met Ala Ala Leu Ser Ala Tyr Ala Ala Gln Arg Pro Pro Ala 
                245                 250                 255     


Pro Pro Gly Glu Gly Ser Leu Glu Pro Gln Tyr Leu Leu Arg Ala Pro 
            260                 265                 270         


Ser Arg Met Pro Arg Pro Leu Leu Ala Pro Ala Ala Pro Gln Lys Trp 
        275                 280                 285             


Pro Ser Pro Leu Gly Asp Ser Glu Asp Pro Ser Ser Thr Gly Asp Gly 
    290                 295                 300                 


Ala Arg Ile His Thr Leu Leu Lys Asp Leu Gln Arg Gln Pro Ala Glu 
305                 310                 315                 320 


Val Arg Gly Leu Ser Gly Leu Glu Leu Asp Gly Met Ala Glu Leu Met 
                325                 330                 335     


Ala Gly Leu Met Gln Gly Val Asp His Gly Val Ala Arg Gly Ser Pro 
            340                 345                 350         


Gly Arg Ala Ala Leu Gly Glu Ser Gly Glu Gln Ala Asp Gly Pro Lys 
        355                 360                 365             


Ala Thr Leu Arg Gly Asp Ser Phe Pro Asp Asp Gly Val Gln Asp Asp 
    370                 375                 380                 


Asp Asp Arg Leu Tyr Gln Glu Val His Arg Leu Ser Ala Thr Leu Gly 
385                 390                 395                 400 


Gly Leu Leu Gln Asp His Gly Ser Arg Leu Leu Pro Gly Ala Leu Pro 
                405                 410                 415     


Phe Ala Arg Pro Leu Asp Met Glu Arg Lys Lys Ser Glu His Pro Glu 
            420                 425                 430         


Ser Ser Leu Ser Ser Glu Glu Glu Thr Ala Gly Val Glu Asn Val Lys 
        435                 440                 445             


Ser Gln Thr Tyr Ser Lys Asp Leu Leu Gly Gln Gln Pro His Ser Glu 
    450                 455                 460                 


Pro Gly Ala Ala Ala Phe Gly Glu Leu Gln Asn Gln Met Pro Gly Pro 
465                 470                 475                 480 


Ser Lys Glu Glu Gln Ser Leu Pro Ala Gly Ala Gln Glu Ala Leu Ser 
                485                 490                 495     


Asp Gly Leu Gln Leu Glu Val Gln Pro Ser Glu Glu Glu Ala Arg Gly 
            500                 505                 510         


Tyr Ile Val Thr Asp Arg Glu Val Leu Gly Pro Ala Val Thr Phe Lys 
        515                 520                 525             


Val Ser Ala Asn Val Gln Asn Val Thr Thr Glu Asp Val Glu Lys Ala 
    530                 535                 540                 


Thr Val Asp Asn Lys Asp Lys Leu Glu Glu Thr Ser Gly Leu Lys Ile 
545                 550                 555                 560 


Leu Gln Thr Gly Val Gly Ser Lys Ser Lys Leu Lys Phe Leu Pro Pro 
                565                 570                 575     


Gln Ala Glu Gln Glu Asp Ser Thr Lys Phe Ile Ala Leu Thr Leu Val 
            580                 585                 590         


Ser Leu Ala Cys Ile Leu Gly Val Leu Leu Ala Ser Gly Leu Ile Tyr 
        595                 600                 605             


Cys Leu Arg His Ser Ser Gln His Arg Leu Lys Glu Lys Leu Ser Gly 
    610                 615                 620                 


Leu Gly Gly Asp Pro Gly Ala Asp Ala Thr Ala Ala Tyr Gln Glu Leu 
625                 630                 635                 640 


Cys Arg Gln Arg Met Ala Thr Arg Pro Pro Asp Arg Pro Glu Gly Pro 
                645                 650                 655     


His Thr Ser Arg Ile Ser Ser Val Ser Ser Gln Phe Ser Asp Gly Pro 
            660                 665                 670         


Ile Pro Ser Pro Ser Ala Arg Ser Ser Ala Ser Ser Trp Ser Glu Glu 
        675                 680                 685             


Pro Val Gln Ser Asn Met Asp Ile Ser Thr Gly His Met Ile Leu Ser 
    690                 695                 700                 


Tyr Met Glu Asp His Leu Lys Asn Lys Asn Arg Leu Glu Lys Glu Trp 
705                 710                 715                 720 


Glu Ala Leu Cys Ala Tyr Gln Ala Glu Pro Asn Ser Ser Phe Val Ala 
                725                 730                 735     


Gln Arg Glu Glu Asn Val Pro Lys Asn Arg Ser Leu Ala Val Leu Thr 
            740                 745                 750         


Tyr Asp His Ser Arg Val Leu Leu Lys Ala Glu Asn Ser His Ser His 
        755                 760                 765             


Ser Asp Tyr Ile Asn Ala Ser Pro Ile Met Asp His Asp Pro Arg Asn 
    770                 775                 780                 


Pro Ala Tyr Ile Ala Thr Gln Gly Pro Leu Pro Ala Thr Val Ala Asp 
785                 790                 795                 800 


Phe Trp Gln Met Val Trp Glu Ser Gly Cys Val Val Ile Val Met Leu 
                805                 810                 815     


Thr Pro Leu Ala Glu Asn Gly Val Arg Gln Cys Tyr His Tyr Trp Pro 
            820                 825                 830         


Asp Glu Gly Ser Asn Leu Tyr His Ile Tyr Glu Val Asn Leu Val Ser 
        835                 840                 845             


Glu His Ile Trp Cys Glu Asp Phe Leu Val Arg Ser Phe Tyr Leu Lys 
    850                 855                 860                 


Asn Leu Gln Thr Asn Glu Thr Arg Thr Val Thr Gln Phe His Phe Leu 
865                 870                 875                 880 


Ser Trp Tyr Asp Arg Gly Val Pro Ser Ser Ser Arg Ser Leu Leu Asp 
                885                 890                 895     


Phe Arg Arg Lys Val Asn Lys Cys Tyr Arg Gly Arg Ser Cys Pro Ile 
            900                 905                 910         


Ile Val His Cys Ser Asp Gly Ala Gly Arg Ser Gly Thr Tyr Val Leu 
        915                 920                 925             


Ile Asp Met Val Leu Asn Lys Met Ala Lys Gly Ala Lys Glu Ile Asp 
    930                 935                 940                 


Ile Ala Ala Thr Leu Glu His Leu Arg Asp Gln Arg Pro Gly Met Val 
945                 950                 955                 960 


Gln Thr Lys Glu Gln Phe Glu Phe Ala Leu Thr Ala Val Ala Glu Glu 
                965                 970                 975     


Val Asn Ala Ile Leu Lys Ala Leu Pro Gln 
            980                 985     


<210>  2757
<211>  870
<212>  PRT
<213>  homo sapiens

<400>  2757

Met Asn Ser Asn Leu Pro Ala Glu Asn Leu Thr Ile Ala Val Asn Met 
1               5                   10                  15      


Thr Lys Thr Leu Pro Thr Ala Val Thr His Gly Phe Asn Ser Thr Asn 
            20                  25                  30          


Asp Pro Pro Ser Met Ser Ile Thr Arg Leu Phe Pro Ala Leu Leu Glu 
        35                  40                  45              


Cys Phe Gly Ile Val Leu Cys Gly Tyr Ile Ala Gly Arg Ala Asn Val 
    50                  55                  60                  


Ile Thr Ser Thr Gln Ala Lys Gly Leu Gly Asn Phe Val Ser Arg Phe 
65                  70                  75                  80  


Ala Leu Pro Ala Leu Leu Phe Lys Asn Met Val Val Leu Asn Phe Ser 
                85                  90                  95      


Asn Val Asp Trp Ser Phe Leu Tyr Ser Ile Leu Ile Ala Lys Ala Ser 
            100                 105                 110         


Val Phe Phe Ile Val Cys Val Leu Thr Leu Leu Val Ala Ser Pro Asp 
        115                 120                 125             


Ser Arg Phe Ser Lys Ala Gly Leu Phe Pro Ile Phe Ala Thr Gln Ser 
    130                 135                 140                 


Asn Asp Phe Ala Leu Gly Tyr Pro Ile Val Glu Ala Leu Tyr Gln Thr 
145                 150                 155                 160 


Thr Tyr Pro Glu Tyr Leu Gln Tyr Ile Tyr Leu Val Ala Pro Ile Ser 
                165                 170                 175     


Leu Met Met Leu Asn Pro Ile Gly Phe Ile Phe Cys Glu Ile Gln Lys 
            180                 185                 190         


Trp Lys Asp Thr Gln Asn Ala Ser Gln Asn Lys Ile Lys Ile Val Gly 
        195                 200                 205             


Leu Gly Leu Leu Arg Val Leu Gln Asn Pro Ile Val Phe Met Val Phe 
    210                 215                 220                 


Ile Gly Ile Ala Phe Asn Phe Ile Leu Asp Arg Lys Val Pro Val Tyr 
225                 230                 235                 240 


Val Glu Asn Phe Leu Asp Gly Leu Gly Asn Ser Phe Ser Gly Ser Ala 
                245                 250                 255     


Leu Phe Tyr Leu Gly Leu Thr Met Val Gly Lys Ile Lys Arg Leu Lys 
            260                 265                 270         


Lys Ser Ala Phe Val Val Leu Ile Leu Leu Ile Thr Ala Lys Leu Leu 
        275                 280                 285             


Val Leu Pro Leu Leu Cys Arg Glu Met Val Glu Leu Leu Asp Lys Gly 
    290                 295                 300                 


Asp Ser Val Val Asn His Thr Ser Leu Ser Asn Tyr Ala Phe Leu Tyr 
305                 310                 315                 320 


Gly Val Phe Pro Val Ala Pro Gly Val Ala Ile Phe Ala Thr Gln Phe 
                325                 330                 335     


Asn Met Glu Val Glu Ile Ile Thr Ser Gly Met Val Ile Ser Thr Phe 
            340                 345                 350         


Val Ser Ala Pro Ile Met Tyr Val Ser Ala Trp Leu Leu Thr Phe Pro 
        355                 360                 365             


Thr Met Asp Pro Lys Pro Leu Ala Tyr Ala Ile Gln Asn Val Ser Phe 
    370                 375                 380                 


Asp Ile Ser Ile Val Ser Leu Ile Ser Leu Ile Trp Ser Leu Ala Ile 
385                 390                 395                 400 


Leu Leu Leu Ser Lys Lys Tyr Lys Gln Leu Pro His Met Leu Thr Thr 
                405                 410                 415     


Asn Leu Leu Ile Ala Gln Ser Ile Val Cys Ala Gly Met Met Ile Trp 
            420                 425                 430         


Asn Phe Val Lys Glu Lys Asn Phe Val Gly Gln Ile Leu Val Phe Val 
        435                 440                 445             


Leu Leu Tyr Ser Ser Leu Tyr Ser Thr Tyr Leu Trp Thr Gly Leu Leu 
    450                 455                 460                 


Ala Ile Ser Leu Phe Leu Leu Lys Lys Arg Glu Arg Val Gln Ile Pro 
465                 470                 475                 480 


Val Gly Ile Ile Ile Ile Ser Gly Trp Gly Ile Pro Ala Leu Leu Val 
                485                 490                 495     


Gly Val Leu Leu Ile Thr Gly Lys His Asn Gly Asp Ser Ile Asp Ser 
            500                 505                 510         


Ala Phe Phe Tyr Gly Lys Glu Gln Met Ile Thr Thr Ala Val Thr Leu 
        515                 520                 525             


Phe Cys Ser Ile Leu Ile Ala Gly Ile Ser Leu Met Cys Met Asn Gln 
    530                 535                 540                 


Thr Ala Gln Ala Gly Ser Tyr Glu Gly Phe Asp Gln Ser Gln Ser His 
545                 550                 555                 560 


Lys Val Val Glu Pro Gly Asn Thr Ala Phe Glu Glu Ser Pro Ala Pro 
                565                 570                 575     


Val Asn Glu Pro Glu Leu Phe Thr Ser Ser Ile Pro Glu Thr Ser Cys 
            580                 585                 590         


Cys Ser Cys Ser Met Gly Asn Gly Glu Leu His Cys Pro Ser Ile Glu 
        595                 600                 605             


Pro Ile Ala Asn Thr Ser Thr Ser Glu Pro Val Ile Pro Ser Phe Glu 
    610                 615                 620                 


Lys Asn Asn His Cys Val Ser Arg Cys Asn Ser Gln Ser Cys Ile Leu 
625                 630                 635                 640 


Ala Gln Glu Glu Glu Gln Tyr Leu Gln Ser Gly Asp Gln Gln Leu Thr 
                645                 650                 655     


Arg His Val Leu Leu Cys Leu Leu Leu Ile Ile Gly Leu Phe Ala Asn 
            660                 665                 670         


Leu Ser Ser Cys Leu Trp Trp Leu Phe Asn Gln Glu Pro Gly Arg Leu 
        675                 680                 685             


Tyr Val Glu Leu Gln Phe Phe Cys Ala Val Phe Asn Phe Gly Gln Gly 
    690                 695                 700                 


Phe Ile Ser Phe Gly Ile Phe Gly Leu Asp Lys His Leu Ile Ile Leu 
705                 710                 715                 720 


Pro Phe Lys Arg Arg Leu Glu Phe Leu Trp Asn Asn Lys Asp Thr Ala 
                725                 730                 735     


Glu Asn Arg Asp Ser Pro Val Ser Glu Glu Ile Lys Met Thr Cys Gln 
            740                 745                 750         


Gln Phe Ile His Tyr His Arg Asp Leu Cys Ile Arg Asn Ile Val Lys 
        755                 760                 765             


Glu Arg Arg Cys Gly Ala Lys Thr Ser Ala Gly Thr Phe Cys Gly Cys 
    770                 775                 780                 


Asp Leu Val Ser Trp Leu Ile Glu Val Gly Leu Ala Ser Asp Arg Gly 
785                 790                 795                 800 


Glu Ala Val Ile Tyr Gly Asp Arg Leu Val Gln Gly Gly Val Ile Gln 
                805                 810                 815     


His Ile Thr Asn Glu Tyr Glu Phe Arg Asp Glu Tyr Leu Phe Tyr Arg 
            820                 825                 830         


Phe Leu Gln Lys Ser Pro Glu Gln Ser Pro Pro Ala Ile Asn Ala Asn 
        835                 840                 845             


Thr Leu Gln Gln Glu Arg Tyr Lys Glu Ile Glu His Ser Ser Pro Pro 
    850                 855                 860                 


Ser His Ser Pro Lys Thr 
865                 870 


<210>  2758
<211>  395
<212>  PRT
<213>  homo sapiens

<400>  2758

Met Ser Leu Val Asp Leu Gly Lys Lys Leu Leu Glu Ala Ala Arg Ala 
1               5                   10                  15      


Gly Gln Asp Asp Glu Val Arg Ile Leu Met Ala Asn Gly Ala Pro Phe 
            20                  25                  30          


Thr Thr Asp Trp Leu Gly Thr Ser Pro Leu His Leu Ala Ala Gln Tyr 
        35                  40                  45              


Gly His Tyr Ser Thr Thr Glu Val Leu Leu Arg Ala Gly Val Ser Arg 
    50                  55                  60                  


Asp Ala Arg Thr Lys Val Asp Arg Thr Pro Leu His Met Ala Ala Ser 
65                  70                  75                  80  


Glu Gly His Ala Ser Ile Val Glu Val Leu Leu Lys His Gly Ala Asp 
                85                  90                  95      


Val Asn Ala Lys Asp Met Leu Lys Met Thr Ala Leu His Trp Ala Thr 
            100                 105                 110         


Glu His Asn His Gln Glu Val Val Glu Leu Leu Ile Lys Tyr Gly Ala 
        115                 120                 125             


Asp Val His Thr Gln Ser Lys Phe Cys Lys Thr Ala Phe Asp Ile Ser 
    130                 135                 140                 


Ile Asp Asn Gly Asn Glu Asp Leu Ala Glu Ile Leu Gln Ile Ala Met 
145                 150                 155                 160 


Gln Asn Gln Ile Asn Thr Asn Pro Glu Ser Pro Asp Thr Val Thr Ile 
                165                 170                 175     


His Ala Ala Thr Pro Gln Phe Ile Ile Gly Pro Gly Gly Val Val Asn 
            180                 185                 190         


Leu Thr Gly Leu Val Ser Ser Glu Asn Ser Ser Lys Ala Thr Asp Glu 
        195                 200                 205             


Thr Gly Val Ser Ala Val Gln Phe Gly Asn Ser Ser Thr Ser Val Leu 
    210                 215                 220                 


Ala Thr Leu Ala Ala Leu Ala Glu Ala Ser Ala Pro Leu Ser Asn Ser 
225                 230                 235                 240 


Ser Glu Thr Pro Val Val Ala Thr Glu Glu Val Val Thr Ala Glu Ser 
                245                 250                 255     


Val Asp Gly Ala Ile Gln Gln Val Val Ser Ser Gly Gly Gln Gln Val 
            260                 265                 270         


Ile Thr Ile Val Thr Asp Gly Ile Gln Leu Gly Asn Leu His Ser Ile 
        275                 280                 285             


Pro Thr Ser Gly Ile Gly Gln Pro Ile Ile Val Thr Met Pro Asp Gly 
    290                 295                 300                 


Gln Gln Val Leu Thr Val Pro Ala Thr Asp Ile Ala Glu Glu Thr Val 
305                 310                 315                 320 


Ile Ser Glu Glu Pro Pro Ala Lys Arg Gln Cys Ile Glu Ile Ile Glu 
                325                 330                 335     


Asn Arg Val Glu Ser Ala Glu Ile Glu Glu Arg Glu Ala Leu Gln Lys 
            340                 345                 350         


Gln Leu Asp Glu Ala Asn Arg Glu Ala Gln Lys Tyr Arg Gln Gln Leu 
        355                 360                 365             


Leu Lys Lys Glu Gln Glu Ala Glu Ala Tyr Arg Gln Lys Leu Glu Ala 
    370                 375                 380                 


Met Thr Arg Leu Gln Thr Asn Lys Glu Ala Val 
385                 390                 395 


<210>  2759
<211>  659
<212>  PRT
<213>  homo sapiens

<400>  2759

Met Ala Ala Phe Ser Lys Tyr Leu Thr Ala Arg Asn Ser Ser Leu Ala 
1               5                   10                  15      


Gly Ala Ala Phe Leu Leu Leu Cys Leu Leu His Lys Arg Arg Arg Ala 
            20                  25                  30          


Leu Gly Leu His Gly Lys Lys Ser Gly Lys Pro Pro Leu Gln Asn Asn 
        35                  40                  45              


Glu Lys Glu Gly Lys Lys Glu Arg Ala Val Val Asp Lys Val Phe Phe 
    50                  55                  60                  


Ser Arg Leu Ile Gln Ile Leu Lys Ile Met Val Pro Arg Thr Phe Cys 
65                  70                  75                  80  


Lys Glu Thr Gly Tyr Leu Val Leu Ile Ala Val Met Leu Val Ser Arg 
                85                  90                  95      


Thr Tyr Cys Asp Val Trp Met Ile Gln Asn Gly Thr Leu Ile Glu Ser 
            100                 105                 110         


Gly Ile Ile Gly Arg Ser Arg Lys Asp Phe Lys Arg Tyr Leu Leu Asn 
        115                 120                 125             


Phe Ile Ala Ala Met Pro Leu Ile Ser Leu Val Asn Asn Phe Leu Lys 
    130                 135                 140                 


Tyr Gly Leu Asn Glu Leu Lys Leu Cys Phe Arg Val Arg Leu Thr Lys 
145                 150                 155                 160 


Tyr Leu Tyr Glu Glu Tyr Leu Gln Ala Phe Thr Tyr Tyr Lys Met Gly 
                165                 170                 175     


Asn Leu Asp Asn Arg Ile Ala Asn Pro Asp Gln Leu Leu Thr Gln Asp 
            180                 185                 190         


Val Glu Lys Phe Cys Asn Ser Val Val Asp Leu Tyr Ser Asn Leu Ser 
        195                 200                 205             


Lys Pro Phe Leu Asp Ile Val Leu Tyr Ile Phe Lys Leu Thr Ser Ala 
    210                 215                 220                 


Ile Gly Ala Gln Gly Pro Ala Ser Met Met Ala Tyr Leu Val Val Ser 
225                 230                 235                 240 


Gly Leu Phe Leu Thr Arg Leu Arg Arg Pro Ile Gly Lys Met Thr Ile 
                245                 250                 255     


Thr Glu Gln Lys Tyr Glu Gly Glu Tyr Arg Tyr Val Asn Ser Arg Leu 
            260                 265                 270         


Ile Thr Asn Ser Glu Glu Ile Ala Phe Tyr Asn Gly Asn Lys Arg Glu 
        275                 280                 285             


Lys Gln Thr Val His Ser Val Phe Arg Lys Leu Val Glu His Leu His 
    290                 295                 300                 


Asn Phe Ile Leu Phe Arg Phe Ser Met Gly Phe Ile Asp Ser Ile Ile 
305                 310                 315                 320 


Ala Lys Tyr Leu Ala Thr Val Val Gly Tyr Leu Val Val Ser Arg Pro 
                325                 330                 335     


Phe Leu Asp Leu Ser His Pro Arg His Leu Lys Ser Thr His Ser Glu 
            340                 345                 350         


Leu Leu Glu Asp Tyr Tyr Gln Ser Gly Arg Met Leu Leu Arg Met Ser 
        355                 360                 365             


Gln Ala Leu Gly Arg Ile Val Leu Ala Gly Arg Glu Met Thr Arg Leu 
    370                 375                 380                 


Ala Gly Phe Thr Ala Arg Ile Thr Glu Leu Met Gln Val Leu Lys Asp 
385                 390                 395                 400 


Leu Asn His Gly Lys Tyr Glu Arg Thr Met Val Ser Gln Gln Glu Lys 
                405                 410                 415     


Gly Ile Glu Gly Val Gln Val Ile Pro Leu Ile Pro Gly Ala Gly Glu 
            420                 425                 430         


Ile Ile Ile Ala Asp Asn Ile Ile Lys Phe Asp His Val Pro Leu Ala 
        435                 440                 445             


Thr Pro Asn Gly Asp Val Leu Ile Arg Asp Leu Asn Phe Glu Val Arg 
    450                 455                 460                 


Ser Gly Ala Asn Val Leu Ile Cys Gly Pro Asn Gly Cys Gly Lys Ser 
465                 470                 475                 480 


Ser Leu Phe Arg Val Leu Gly Glu Leu Trp Pro Leu Phe Gly Gly Arg 
                485                 490                 495     


Leu Thr Lys Pro Glu Arg Gly Lys Leu Phe Tyr Val Pro Gln Arg Pro 
            500                 505                 510         


Tyr Met Thr Leu Gly Thr Leu Arg Asp Gln Val Ile Tyr Pro Asp Gly 
        515                 520                 525             


Arg Glu Asp Gln Lys Arg Lys Gly Ile Ser Asp Leu Val Leu Lys Glu 
    530                 535                 540                 


Tyr Leu Asp Asn Val Gln Leu Gly His Ile Leu Glu Arg Glu Gly Gly 
545                 550                 555                 560 


Trp Asp Ser Val Gln Asp Trp Met Asp Val Leu Ser Gly Gly Glu Lys 
                565                 570                 575     


Gln Arg Met Ala Met Ala Arg Leu Phe Tyr His Lys Pro Gln Phe Ala 
            580                 585                 590         


Ile Leu Asp Glu Cys Thr Ser Ala Val Ser Val Asp Val Glu Gly Tyr 
        595                 600                 605             


Ile Tyr Ser His Cys Arg Lys Val Gly Ile Thr Leu Phe Thr Val Ser 
    610                 615                 620                 


His Arg Lys Ser Leu Trp Lys His His Glu Tyr Tyr Leu His Met Asp 
625                 630                 635                 640 


Gly Arg Gly Asn Tyr Glu Phe Lys Gln Ile Thr Glu Asp Thr Val Glu 
                645                 650                 655     


Phe Gly Ser 
            


<210>  2760
<211>  777
<212>  PRT
<213>  homo sapiens

<400>  2760

Met Asp Ser Lys Glu Ser Leu Thr Pro Gly Arg Glu Glu Asn Pro Ser 
1               5                   10                  15      


Ser Val Leu Ala Gln Glu Arg Gly Asp Val Met Asp Phe Tyr Lys Thr 
            20                  25                  30          


Leu Arg Gly Gly Ala Thr Val Lys Val Ser Ala Ser Ser Pro Ser Leu 
        35                  40                  45              


Ala Val Ala Ser Gln Ser Asp Ser Lys Gln Arg Arg Leu Leu Val Asp 
    50                  55                  60                  


Phe Pro Lys Gly Ser Val Ser Asn Ala Gln Gln Pro Asp Leu Ser Lys 
65                  70                  75                  80  


Ala Val Ser Leu Ser Met Gly Leu Tyr Met Gly Glu Thr Glu Thr Lys 
                85                  90                  95      


Val Met Gly Asn Asp Leu Gly Phe Pro Gln Gln Gly Gln Ile Ser Leu 
            100                 105                 110         


Ser Ser Gly Glu Thr Asp Leu Lys Leu Leu Glu Glu Ser Ile Ala Asn 
        115                 120                 125             


Leu Asn Arg Ser Thr Ser Val Pro Glu Asn Pro Lys Ser Ser Ala Ser 
    130                 135                 140                 


Thr Ala Val Ser Ala Ala Pro Thr Glu Lys Glu Phe Pro Lys Thr His 
145                 150                 155                 160 


Ser Asp Val Ser Ser Glu Gln Gln His Leu Lys Gly Gln Thr Gly Thr 
                165                 170                 175     


Asn Gly Gly Asn Val Lys Leu Tyr Thr Thr Asp Gln Ser Thr Phe Asp 
            180                 185                 190         


Ile Leu Gln Asp Leu Glu Phe Ser Ser Gly Ser Pro Gly Lys Glu Thr 
        195                 200                 205             


Asn Glu Ser Pro Trp Arg Ser Asp Leu Leu Ile Asp Glu Asn Cys Leu 
    210                 215                 220                 


Leu Ser Pro Leu Ala Gly Glu Asp Asp Ser Phe Leu Leu Glu Gly Asn 
225                 230                 235                 240 


Ser Asn Glu Asp Cys Lys Pro Leu Ile Leu Pro Asp Thr Lys Pro Lys 
                245                 250                 255     


Ile Lys Asp Asn Gly Asp Leu Val Leu Ser Ser Pro Ser Asn Val Thr 
            260                 265                 270         


Leu Pro Gln Val Lys Thr Glu Lys Glu Asp Phe Ile Glu Leu Cys Thr 
        275                 280                 285             


Pro Gly Val Ile Lys Gln Glu Lys Leu Gly Thr Val Tyr Cys Gln Ala 
    290                 295                 300                 


Ser Phe Pro Gly Ala Asn Ile Ile Gly Asn Lys Met Ser Ala Ile Ser 
305                 310                 315                 320 


Val His Gly Val Ser Thr Ser Gly Gly Gln Met Tyr His Tyr Asp Met 
                325                 330                 335     


Asn Thr Ala Ser Leu Ser Gln Gln Gln Asp Gln Lys Pro Ile Phe Asn 
            340                 345                 350         


Val Ile Pro Pro Ile Pro Val Gly Ser Glu Asn Trp Asn Arg Cys Gln 
        355                 360                 365             


Gly Ser Gly Asp Asp Asn Leu Thr Ser Leu Gly Thr Leu Asn Phe Pro 
    370                 375                 380                 


Gly Arg Thr Val Phe Ser Asn Gly Tyr Ser Ser Pro Ser Met Arg Pro 
385                 390                 395                 400 


Asp Val Ser Ser Pro Pro Ser Ser Ser Ser Thr Ala Thr Thr Gly Pro 
                405                 410                 415     


Pro Pro Lys Leu Cys Leu Val Cys Ser Asp Glu Ala Ser Gly Cys His 
            420                 425                 430         


Tyr Gly Val Leu Thr Cys Gly Ser Cys Lys Val Phe Phe Lys Arg Ala 
        435                 440                 445             


Val Glu Gly Gln His Asn Tyr Leu Cys Ala Gly Arg Asn Asp Cys Ile 
    450                 455                 460                 


Ile Asp Lys Ile Arg Arg Lys Asn Cys Pro Ala Cys Arg Tyr Arg Lys 
465                 470                 475                 480 


Cys Leu Gln Ala Gly Met Asn Leu Glu Ala Arg Lys Thr Lys Lys Lys 
                485                 490                 495     


Ile Lys Gly Ile Gln Gln Ala Thr Thr Gly Val Ser Gln Glu Thr Ser 
            500                 505                 510         


Glu Asn Pro Gly Asn Lys Thr Ile Val Pro Ala Thr Leu Pro Gln Leu 
        515                 520                 525             


Thr Pro Thr Leu Val Ser Leu Leu Glu Val Ile Glu Pro Glu Val Leu 
    530                 535                 540                 


Tyr Ala Gly Tyr Asp Ser Ser Val Pro Asp Ser Thr Trp Arg Ile Met 
545                 550                 555                 560 


Thr Thr Leu Asn Met Leu Gly Gly Arg Gln Val Ile Ala Ala Val Lys 
                565                 570                 575     


Trp Ala Lys Ala Ile Pro Gly Phe Arg Asn Leu His Leu Asp Asp Gln 
            580                 585                 590         


Met Thr Leu Leu Gln Tyr Ser Trp Met Phe Leu Met Ala Phe Ala Leu 
        595                 600                 605             


Gly Trp Arg Ser Tyr Arg Gln Ser Ser Ala Asn Leu Leu Cys Phe Ala 
    610                 615                 620                 


Pro Asp Leu Ile Ile Asn Glu Gln Arg Met Thr Leu Pro Cys Met Tyr 
625                 630                 635                 640 


Asp Gln Cys Lys His Met Leu Tyr Val Ser Ser Glu Leu His Arg Leu 
                645                 650                 655     


Gln Val Ser Tyr Glu Glu Tyr Leu Cys Met Lys Thr Leu Leu Leu Leu 
            660                 665                 670         


Ser Ser Val Pro Lys Asp Gly Leu Lys Ser Gln Glu Leu Phe Asp Glu 
        675                 680                 685             


Ile Arg Met Thr Tyr Ile Lys Glu Leu Gly Lys Ala Ile Val Lys Arg 
    690                 695                 700                 


Glu Gly Asn Ser Ser Gln Asn Trp Gln Arg Phe Tyr Gln Leu Thr Lys 
705                 710                 715                 720 


Leu Leu Asp Ser Met His Glu Val Val Glu Asn Leu Leu Asn Tyr Cys 
                725                 730                 735     


Phe Gln Thr Phe Leu Asp Lys Thr Met Ser Ile Glu Phe Pro Glu Met 
            740                 745                 750         


Leu Ala Glu Ile Ile Thr Asn Gln Ile Pro Lys Tyr Ser Asn Gly Asn 
        755                 760                 765             


Ile Lys Lys Leu Leu Phe His Gln Lys 
    770                 775         


<210>  2761
<211>  422
<212>  PRT
<213>  homo sapiens

<400>  2761

Met Gln Asn Ser His Ser Gly Val Asn Gln Leu Gly Gly Val Phe Val 
1               5                   10                  15      


Asn Gly Arg Pro Leu Pro Asp Ser Thr Arg Gln Lys Ile Val Glu Leu 
            20                  25                  30          


Ala His Ser Gly Ala Arg Pro Cys Asp Ile Ser Arg Ile Leu Gln Val 
        35                  40                  45              


Ser Asn Gly Cys Val Ser Lys Ile Leu Gly Arg Tyr Tyr Glu Thr Gly 
    50                  55                  60                  


Ser Ile Arg Pro Arg Ala Ile Gly Gly Ser Lys Pro Arg Val Ala Thr 
65                  70                  75                  80  


Pro Glu Val Val Ser Lys Ile Ala Gln Tyr Lys Arg Glu Cys Pro Ser 
                85                  90                  95      


Ile Phe Ala Trp Glu Ile Arg Asp Arg Leu Leu Ser Glu Gly Val Cys 
            100                 105                 110         


Thr Asn Asp Asn Ile Pro Ser Val Ser Ser Ile Asn Arg Val Leu Arg 
        115                 120                 125             


Asn Leu Ala Ser Glu Lys Gln Gln Met Gly Ala Asp Gly Met Tyr Asp 
    130                 135                 140                 


Lys Leu Arg Met Leu Asn Gly Gln Thr Gly Ser Trp Gly Thr Arg Pro 
145                 150                 155                 160 


Gly Trp Tyr Pro Gly Thr Ser Val Pro Gly Gln Pro Thr Gln Asp Gly 
                165                 170                 175     


Cys Gln Gln Gln Glu Gly Gly Gly Glu Asn Thr Asn Ser Ile Ser Ser 
            180                 185                 190         


Asn Gly Glu Asp Ser Asp Glu Ala Gln Met Arg Leu Gln Leu Lys Arg 
        195                 200                 205             


Lys Leu Gln Arg Asn Arg Thr Ser Phe Thr Gln Glu Gln Ile Glu Ala 
    210                 215                 220                 


Leu Glu Lys Glu Phe Glu Arg Thr His Tyr Pro Asp Val Phe Ala Arg 
225                 230                 235                 240 


Glu Arg Leu Ala Ala Lys Ile Asp Leu Pro Glu Ala Arg Ile Gln Val 
                245                 250                 255     


Trp Phe Ser Asn Arg Arg Ala Lys Trp Arg Arg Glu Glu Lys Leu Arg 
            260                 265                 270         


Asn Gln Arg Arg Gln Ala Ser Asn Thr Pro Ser His Ile Pro Ile Ser 
        275                 280                 285             


Ser Ser Phe Ser Thr Ser Val Tyr Gln Pro Ile Pro Gln Pro Thr Thr 
    290                 295                 300                 


Pro Val Ser Ser Phe Thr Ser Gly Ser Met Leu Gly Arg Thr Asp Thr 
305                 310                 315                 320 


Ala Leu Thr Asn Thr Tyr Ser Ala Leu Pro Pro Met Pro Ser Phe Thr 
                325                 330                 335     


Met Ala Asn Asn Leu Pro Met Gln Pro Pro Val Pro Ser Gln Thr Ser 
            340                 345                 350         


Ser Tyr Ser Cys Met Leu Pro Thr Ser Pro Ser Val Asn Gly Arg Ser 
        355                 360                 365             


Tyr Asp Thr Tyr Thr Pro Pro His Met Gln Thr His Met Asn Ser Gln 
    370                 375                 380                 


Pro Met Gly Thr Ser Gly Thr Thr Ser Thr Gly Leu Ile Ser Pro Gly 
385                 390                 395                 400 


Val Ser Val Pro Val Gln Val Pro Gly Ser Glu Pro Asp Met Ser Gln 
                405                 410                 415     


Tyr Trp Pro Arg Leu Gln 
            420         


<210>  2762
<211>  331
<212>  PRT
<213>  homo sapiens

<400>  2762

Met Thr Ala Lys Met Glu Thr Thr Phe Tyr Asp Asp Ala Leu Asn Ala 
1               5                   10                  15      


Ser Phe Leu Pro Ser Glu Ser Gly Pro Tyr Gly Tyr Ser Asn Pro Lys 
            20                  25                  30          


Ile Leu Lys Gln Ser Met Thr Leu Asn Leu Ala Asp Pro Val Gly Ser 
        35                  40                  45              


Leu Lys Pro His Leu Arg Ala Lys Asn Ser Asp Leu Leu Thr Ser Pro 
    50                  55                  60                  


Asp Val Gly Leu Leu Lys Leu Ala Ser Pro Glu Leu Glu Arg Leu Ile 
65                  70                  75                  80  


Ile Gln Ser Ser Asn Gly His Ile Thr Thr Thr Pro Thr Pro Thr Gln 
                85                  90                  95      


Phe Leu Cys Pro Lys Asn Val Thr Asp Glu Gln Glu Gly Phe Ala Glu 
            100                 105                 110         


Gly Phe Val Arg Ala Leu Ala Glu Leu His Ser Gln Asn Thr Leu Pro 
        115                 120                 125             


Ser Val Thr Ser Ala Ala Gln Pro Val Asn Gly Ala Gly Met Val Ala 
    130                 135                 140                 


Pro Ala Val Ala Ser Val Ala Gly Gly Ser Gly Ser Gly Gly Phe Ser 
145                 150                 155                 160 


Ala Ser Leu His Ser Glu Pro Pro Val Tyr Ala Asn Leu Ser Asn Phe 
                165                 170                 175     


Asn Pro Gly Ala Leu Ser Ser Gly Gly Gly Ala Pro Ser Tyr Gly Ala 
            180                 185                 190         


Ala Gly Leu Ala Phe Pro Ala Gln Pro Gln Gln Gln Gln Gln Pro Pro 
        195                 200                 205             


His His Leu Pro Gln Gln Met Pro Val Gln His Pro Arg Leu Gln Ala 
    210                 215                 220                 


Leu Lys Glu Glu Pro Gln Thr Val Pro Glu Met Pro Gly Glu Thr Pro 
225                 230                 235                 240 


Pro Leu Ser Pro Ile Asp Met Glu Ser Gln Glu Arg Ile Lys Ala Glu 
                245                 250                 255     


Arg Lys Arg Met Arg Asn Arg Ile Ala Ala Ser Lys Cys Arg Lys Arg 
            260                 265                 270         


Lys Leu Glu Arg Ile Ala Arg Leu Glu Glu Lys Val Lys Thr Leu Lys 
        275                 280                 285             


Ala Gln Asn Ser Glu Leu Ala Ser Thr Ala Asn Met Leu Arg Glu Gln 
    290                 295                 300                 


Val Ala Gln Leu Lys Gln Lys Val Met Asn His Val Asn Ser Gly Cys 
305                 310                 315                 320 


Gln Leu Met Leu Thr Gln Gln Leu Gln Thr Phe 
                325                 330     


<210>  2763
<211>  680
<212>  PRT
<213>  homo sapiens

<400>  2763

Met Val Pro Gly Val Pro Gly Ala Val Leu Thr Leu Cys Leu Trp Leu 
1               5                   10                  15      


Ala Ala Ser Ser Gly Cys Leu Ala Ala Gly Pro Gly Ala Ala Ala Ala 
            20                  25                  30          


Arg Arg Leu Asp Glu Ser Leu Ser Ala Gly Ser Val Gln Arg Ala Arg 
        35                  40                  45              


Cys Ala Ser Arg Cys Leu Ser Leu Gln Ile Thr Arg Ile Ser Ala Phe 
    50                  55                  60                  


Phe Gln His Phe Gln Asn Asn Gly Ser Leu Val Trp Cys Gln Asn His 
65                  70                  75                  80  


Lys Gln Cys Ser Lys Cys Leu Glu Pro Cys Lys Glu Ser Gly Asp Leu 
                85                  90                  95      


Arg Lys His Gln Cys Gln Ser Phe Cys Glu Pro Leu Phe Pro Lys Lys 
            100                 105                 110         


Ser Tyr Glu Cys Leu Thr Ser Cys Glu Phe Leu Lys Tyr Ile Leu Leu 
        115                 120                 125             


Val Lys Gln Gly Asp Cys Pro Ala Pro Glu Lys Ala Ser Gly Phe Ala 
    130                 135                 140                 


Ala Ala Cys Val Glu Ser Cys Glu Val Asp Asn Glu Cys Ser Gly Val 
145                 150                 155                 160 


Lys Lys Cys Cys Ser Asn Gly Cys Gly His Thr Cys Gln Val Pro Lys 
                165                 170                 175     


Thr Leu Tyr Lys Gly Val Pro Leu Lys Pro Arg Lys Glu Leu Arg Phe 
            180                 185                 190         


Thr Glu Leu Gln Ser Gly Gln Leu Glu Val Lys Trp Ser Ser Lys Phe 
        195                 200                 205             


Asn Ile Ser Ile Glu Pro Val Ile Tyr Val Val Gln Arg Arg Trp Asn 
    210                 215                 220                 


Tyr Gly Ile His Pro Ser Glu Asp Asp Ala Thr His Trp Gln Thr Val 
225                 230                 235                 240 


Ala Gln Thr Thr Asp Glu Arg Val Gln Leu Thr Asp Ile Arg Pro Ser 
                245                 250                 255     


Arg Trp Tyr Gln Phe Arg Val Ala Ala Val Asn Val His Gly Thr Arg 
            260                 265                 270         


Gly Phe Thr Ala Pro Ser Lys His Phe Arg Ser Ser Lys Asp Pro Ser 
        275                 280                 285             


Ala Pro Pro Ala Pro Ala Asn Leu Arg Leu Ala Asn Ser Thr Val Asn 
    290                 295                 300                 


Ser Asp Gly Ser Val Thr Val Thr Ile Val Trp Asp Leu Pro Glu Glu 
305                 310                 315                 320 


Pro Asp Ile Pro Val His His Tyr Lys Val Phe Trp Ser Trp Met Val 
                325                 330                 335     


Ser Ser Lys Ser Leu Val Pro Thr Lys Lys Lys Arg Arg Lys Thr Thr 
            340                 345                 350         


Asp Gly Phe Gln Asn Ser Val Ile Leu Glu Lys Leu Gln Pro Asp Cys 
        355                 360                 365             


Asp Tyr Val Val Glu Leu Gln Ala Ile Thr Tyr Trp Gly Gln Thr Arg 
    370                 375                 380                 


Leu Lys Ser Ala Lys Val Ser Leu His Phe Thr Ser Thr His Ala Thr 
385                 390                 395                 400 


Asn Asn Lys Glu Gln Leu Val Lys Thr Arg Lys Gly Gly Ile Gln Thr 
                405                 410                 415     


Gln Leu Pro Phe Gln Arg Arg Arg Pro Thr Arg Pro Leu Glu Val Gly 
            420                 425                 430         


Ala Pro Phe Tyr Gln Asp Gly Gln Leu Gln Val Lys Val Tyr Trp Lys 
        435                 440                 445             


Lys Thr Glu Asp Pro Thr Val Asn Arg Tyr His Val Arg Trp Phe Pro 
    450                 455                 460                 


Glu Ala Cys Ala His Asn Arg Thr Thr Gly Ser Glu Ala Ser Ser Gly 
465                 470                 475                 480 


Met Thr His Glu Asn Tyr Ile Ile Leu Gln Asp Leu Ser Phe Ser Cys 
                485                 490                 495     


Lys Tyr Lys Val Thr Val Gln Pro Ile Arg Pro Lys Ser His Ser Lys 
            500                 505                 510         


Ala Glu Ala Val Phe Phe Thr Thr Pro Pro Cys Ser Ala Leu Lys Gly 
        515                 520                 525             


Lys Ser His Lys Pro Val Gly Cys Leu Gly Glu Ala Gly His Val Leu 
    530                 535                 540                 


Ser Lys Val Leu Ala Lys Pro Glu Asn Leu Ser Ala Ser Phe Ile Val 
545                 550                 555                 560 


Gln Asp Val Asn Ile Thr Gly His Phe Ser Trp Lys Met Ala Lys Ala 
                565                 570                 575     


Asn Leu Tyr Gln Pro Met Thr Gly Phe Gln Val Thr Trp Ala Glu Val 
            580                 585                 590         


Thr Thr Glu Ser Arg Gln Asn Ser Leu Pro Asn Ser Ile Ile Ser Gln 
        595                 600                 605             


Ser Gln Ile Leu Pro Ser Asp His Tyr Val Leu Thr Val Pro Asn Leu 
    610                 615                 620                 


Arg Pro Ser Thr Leu Tyr Arg Leu Glu Val Gln Val Leu Thr Pro Gly 
625                 630                 635                 640 


Gly Glu Gly Pro Ala Thr Ile Lys Thr Phe Arg Thr Pro Glu Leu Pro 
                645                 650                 655     


Pro Ser Ser Ala His Arg Ser His Leu Lys His Arg His Pro His His 
            660                 665                 670         


Tyr Lys Pro Ser Pro Glu Arg Tyr 
        675                 680 


<210>  2764
<211>  737
<212>  PRT
<213>  homo sapiens

<400>  2764

Met Gln Pro Arg Arg Ala Gln Ala Pro Gly Ala Gln Leu Leu Pro Ala 
1               5                   10                  15      


Leu Ala Leu Leu Leu Leu Leu Leu Gly Ala Gly Pro Arg Gly Ser Ser 
            20                  25                  30          


Leu Ala Asn Pro Val Pro Ala Ala Pro Leu Ser Ala Pro Gly Pro Cys 
        35                  40                  45              


Ala Ala Gln Pro Cys Arg Asn Gly Gly Val Cys Thr Ser Arg Pro Glu 
    50                  55                  60                  


Pro Asp Pro Gln His Pro Ala Pro Ala Gly Glu Pro Gly Tyr Ser Cys 
65                  70                  75                  80  


Thr Cys Pro Ala Gly Ile Ser Gly Ala Asn Cys Gln Leu Val Ala Asp 
                85                  90                  95      


Pro Cys Ala Ser Asn Pro Cys His His Gly Asn Cys Ser Ser Ser Ser 
            100                 105                 110         


Ser Ser Ser Ser Asp Gly Tyr Leu Cys Ile Cys Asn Glu Gly Tyr Glu 
        115                 120                 125             


Gly Pro Asn Cys Glu Gln Ala Leu Pro Ser Leu Pro Ala Thr Gly Trp 
    130                 135                 140                 


Thr Glu Ser Met Ala Pro Arg Gln Leu Gln Pro Val Pro Ala Thr Gln 
145                 150                 155                 160 


Glu Pro Asp Lys Ile Leu Pro Arg Ser Gln Ala Thr Val Thr Leu Pro 
                165                 170                 175     


Thr Trp Gln Pro Lys Thr Gly Gln Lys Val Val Glu Met Lys Trp Asp 
            180                 185                 190         


Gln Val Glu Val Ile Pro Asp Ile Ala Cys Gly Asn Ala Ser Ser Asn 
        195                 200                 205             


Ser Ser Ala Gly Gly Arg Leu Val Ser Phe Glu Val Pro Gln Asn Thr 
    210                 215                 220                 


Ser Val Lys Ile Arg Gln Asp Ala Thr Ala Ser Leu Ile Leu Leu Trp 
225                 230                 235                 240 


Lys Val Thr Ala Thr Gly Phe Gln Gln Cys Ser Leu Ile Asp Gly Arg 
                245                 250                 255     


Ser Val Thr Pro Leu Gln Ala Ser Gly Gly Leu Val Leu Leu Glu Glu 
            260                 265                 270         


Met Leu Ala Leu Gly Asn Asn His Phe Ile Gly Phe Val Asn Asp Ser 
        275                 280                 285             


Val Thr Lys Ser Ile Val Ala Leu Arg Leu Thr Leu Val Val Lys Val 
    290                 295                 300                 


Ser Thr Cys Val Pro Gly Glu Ser His Ala Asn Asp Leu Glu Cys Ser 
305                 310                 315                 320 


Gly Lys Gly Lys Cys Thr Thr Lys Pro Ser Glu Ala Thr Phe Ser Cys 
                325                 330                 335     


Thr Cys Glu Glu Gln Tyr Val Gly Thr Phe Cys Glu Glu Tyr Asp Ala 
            340                 345                 350         


Cys Gln Arg Lys Pro Cys Gln Asn Asn Ala Ser Cys Ile Asp Ala Asn 
        355                 360                 365             


Glu Lys Gln Asp Gly Ser Asn Phe Thr Cys Val Cys Leu Pro Gly Tyr 
    370                 375                 380                 


Thr Gly Glu Leu Cys Gln Ser Lys Ile Asp Tyr Cys Ile Leu Asp Pro 
385                 390                 395                 400 


Cys Arg Asn Gly Ala Thr Cys Ile Ser Ser Leu Ser Gly Phe Thr Cys 
                405                 410                 415     


Gln Cys Pro Glu Gly Tyr Phe Gly Ser Ala Cys Glu Glu Lys Val Asp 
            420                 425                 430         


Pro Cys Ala Ser Ser Pro Cys Gln Asn Asn Gly Thr Cys Tyr Val Asp 
        435                 440                 445             


Gly Val His Phe Thr Cys Asn Cys Ser Pro Gly Phe Thr Gly Pro Thr 
    450                 455                 460                 


Cys Ala Gln Leu Ile Asp Phe Cys Ala Leu Ser Pro Cys Ala His Gly 
465                 470                 475                 480 


Thr Cys Arg Ser Val Gly Thr Ser Tyr Lys Cys Leu Cys Asp Pro Gly 
                485                 490                 495     


Tyr His Gly Leu Tyr Cys Glu Glu Glu Tyr Asn Glu Cys Leu Ser Ala 
            500                 505                 510         


Pro Cys Leu Asn Ala Ala Thr Cys Arg Asp Leu Val Asn Gly Tyr Glu 
        515                 520                 525             


Cys Val Cys Leu Ala Glu Tyr Lys Gly Thr His Cys Glu Leu Tyr Lys 
    530                 535                 540                 


Asp Pro Cys Ala Asn Val Ser Cys Leu Asn Gly Ala Thr Cys Asp Ser 
545                 550                 555                 560 


Asp Gly Leu Asn Gly Thr Cys Ile Cys Ala Pro Gly Phe Thr Gly Glu 
                565                 570                 575     


Glu Cys Asp Ile Asp Ile Asn Glu Cys Asp Ser Asn Pro Cys His His 
            580                 585                 590         


Gly Gly Ser Cys Leu Asp Gln Pro Asn Gly Tyr Asn Cys His Cys Pro 
        595                 600                 605             


His Gly Trp Val Gly Ala Asn Cys Glu Ile His Leu Gln Trp Lys Ser 
    610                 615                 620                 


Gly His Met Ala Glu Ser Leu Thr Asn Met Pro Arg His Ser Leu Tyr 
625                 630                 635                 640 


Ile Ile Ile Gly Ala Leu Cys Val Ala Phe Ile Leu Met Leu Ile Ile 
                645                 650                 655     


Leu Ile Val Gly Ile Cys Arg Ile Ser Arg Ile Glu Tyr Gln Gly Ser 
            660                 665                 670         


Ser Arg Pro Ala Tyr Glu Glu Phe Tyr Asn Cys Arg Ser Ile Asp Ser 
        675                 680                 685             


Glu Phe Ser Asn Ala Ile Ala Ser Ile Arg His Ala Arg Phe Gly Lys 
    690                 695                 700                 


Lys Ser Arg Pro Ala Met Tyr Asp Val Ser Pro Ile Ala Tyr Glu Asp 
705                 710                 715                 720 


Tyr Ser Pro Asp Asp Lys Pro Leu Val Thr Leu Ile Lys Thr Lys Asp 
                725                 730                 735     


Leu 
    


<210>  2765
<211>  371
<212>  PRT
<213>  homo sapiens

<400>  2765

Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Pro Gly Gln Thr Pro Glu Ala Ala Lys Glu Ala Glu Leu Ala Ala Arg 
            20                  25                  30          


Ile Leu Leu Asp Gln Gly Gln Thr His Ser Val Glu Thr Pro Tyr Gly 
        35                  40                  45              


Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg Pro Ala 
    50                  55                  60                  


Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys Phe Gln 
65                  70                  75                  80  


Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn Phe Val 
                85                  90                  95      


Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro Val Phe 
            100                 105                 110         


Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp Met Ile 
        115                 120                 125             


Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly Val Gly 
    130                 135                 140                 


Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn His Pro 
145                 150                 155                 160 


Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn Ala Lys 
                165                 170                 175     


Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr Ser Ser 
            180                 185                 190         


Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu Leu Ser 
        195                 200                 205             


Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr His Ala 
    210                 215                 220                 


Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn Asn Arg 
225                 230                 235                 240 


Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg Cys Pro 
                245                 250                 255     


Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala Val Val 
            260                 265                 270         


Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu Lys Met 
        275                 280                 285             


Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Gln Pro Gly Lys Leu Thr 
    290                 295                 300                 


Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr Met Ala Ser Ser 
305                 310                 315                 320 


Cys Met Thr Arg Leu Ser Arg Ser Arg Thr Ala Ser Leu Thr Ser Ala 
                325                 330                 335     


Ala Ser Val Asp Gly Asn Arg Ser Arg Ser Arg Thr Leu Ser Gln Ser 
            340                 345                 350         


Ser Glu Ser Gly Thr Leu Ser Ser Gly Pro Pro Gly His Thr Met Glu 
        355                 360                 365             


Val Ser Cys 
    370     


<210>  2766
<211>  699
<212>  PRT
<213>  homo sapiens

<400>  2766

Met Ala Asp Pro Glu Val Cys Cys Phe Ile Thr Lys Ile Leu Cys Ala 
1               5                   10                  15      


His Gly Gly Arg Met Ala Leu Asp Ala Leu Leu Gln Glu Ile Ala Leu 
            20                  25                  30          


Ser Glu Pro Gln Leu Cys Glu Val Leu Gln Val Ala Gly Pro Asp Arg 
        35                  40                  45              


Phe Val Val Leu Glu Thr Gly Gly Glu Ala Gly Ile Thr Arg Ser Val 
    50                  55                  60                  


Val Ala Thr Thr Arg Ala Arg Val Cys Arg Arg Lys Tyr Cys Gln Arg 
65                  70                  75                  80  


Pro Cys Asp Asn Leu His Leu Cys Lys Leu Asn Leu Leu Gly Arg Cys 
                85                  90                  95      


Asn Tyr Ser Gln Ser Glu Arg Asn Leu Cys Lys Tyr Ser His Glu Val 
            100                 105                 110         


Leu Ser Glu Glu Asn Phe Lys Val Leu Lys Asn His Glu Leu Ser Gly 
        115                 120                 125             


Leu Asn Lys Glu Glu Leu Ala Val Leu Leu Leu Gln Ser Asp Pro Phe 
    130                 135                 140                 


Phe Met Pro Glu Ile Cys Lys Ser Tyr Lys Gly Glu Gly Arg Gln Gln 
145                 150                 155                 160 


Ile Cys Asn Gln Gln Pro Pro Cys Ser Arg Leu His Ile Cys Asp His 
                165                 170                 175     


Phe Thr Arg Gly Asn Cys Arg Phe Pro Asn Cys Leu Arg Ser His Asn 
            180                 185                 190         


Leu Met Asp Arg Lys Val Leu Ala Ile Met Arg Glu His Gly Leu Asn 
        195                 200                 205             


Pro Asp Val Val Gln Asn Ile Gln Asp Ile Cys Asn Ser Lys His Met 
    210                 215                 220                 


Gln Lys Asn Pro Pro Gly Pro Arg Ala Pro Ser Ser His Arg Arg Asn 
225                 230                 235                 240 


Met Ala Tyr Arg Ala Arg Ser Lys Ser Arg Asp Arg Phe Phe Gln Gly 
                245                 250                 255     


Ser Gln Glu Phe Leu Ala Ser Ala Ser Ala Ser Ala Glu Arg Ser Cys 
            260                 265                 270         


Thr Pro Ser Pro Asp Gln Ile Ser His Arg Ala Ser Leu Glu Asp Ala 
        275                 280                 285             


Pro Val Asp Asp Leu Thr Arg Lys Phe Thr Tyr Leu Gly Ser Gln Asp 
    290                 295                 300                 


Arg Ala Arg Pro Pro Ser Gly Ser Ser Lys Ala Thr Asp Leu Gly Gly 
305                 310                 315                 320 


Thr Ser Gln Ala Gly Thr Ser Gln Arg Phe Leu Glu Asn Gly Ser Gln 
                325                 330                 335     


Glu Asp Leu Leu His Gly Asn Pro Gly Ser Thr Tyr Leu Ala Ser Asn 
            340                 345                 350         


Ser Thr Ser Ala Pro Asn Trp Lys Ser Leu Thr Ser Trp Thr Asn Asp 
        355                 360                 365             


Gln Gly Ala Arg Arg Lys Thr Val Phe Ser Pro Thr Leu Pro Ala Ala 
    370                 375                 380                 


Arg Ser Ser Leu Gly Ser Leu Gln Thr Pro Glu Ala Val Thr Thr Arg 
385                 390                 395                 400 


Lys Gly Thr Gly Leu Leu Ser Ser Asp Tyr Arg Ile Ile Asn Gly Lys 
                405                 410                 415     


Ser Gly Thr Gln Asp Ile Gln Pro Gly Pro Leu Phe Asn Asn Asn Ala 
            420                 425                 430         


Asp Gly Val Ala Thr Asp Ile Thr Ser Thr Arg Ser Leu Asn Tyr Lys 
        435                 440                 445             


Ser Thr Ser Ser Gly His Arg Glu Ile Ser Ser Pro Arg Ile Gln Asp 
    450                 455                 460                 


Ala Gly Pro Ala Ser Arg Asp Val Gln Ala Thr Gly Arg Ile Ala Asp 
465                 470                 475                 480 


Asp Ala Asp Pro Arg Val Ala Leu Val Asn Asp Ser Leu Ser Asp Val 
                485                 490                 495     


Thr Ser Thr Thr Ser Ser Arg Val Asp Asp His Asp Ser Glu Glu Ile 
            500                 505                 510         


Cys Leu Asp His Leu Cys Lys Gly Cys Pro Leu Asn Gly Ser Cys Ser 
        515                 520                 525             


Lys Val His Phe His Leu Pro Tyr Arg Trp Gln Met Leu Ile Gly Lys 
    530                 535                 540                 


Thr Trp Thr Asp Phe Glu His Met Glu Thr Ile Glu Lys Gly Tyr Cys 
545                 550                 555                 560 


Asn Pro Gly Ile His Leu Cys Ser Val Gly Ser Tyr Thr Ile Asn Phe 
                565                 570                 575     


Arg Val Met Ser Cys Asp Ser Phe Pro Ile Arg Arg Leu Ser Thr Pro 
            580                 585                 590         


Ser Ser Val Thr Lys Pro Ala Asn Ser Val Phe Thr Thr Lys Trp Ile 
        595                 600                 605             


Trp Tyr Trp Lys Asn Glu Ser Gly Thr Trp Ile Gln Tyr Gly Glu Glu 
    610                 615                 620                 


Lys Asp Lys Arg Lys Asn Ser Asn Val Asp Ser Ser Tyr Leu Glu Ser 
625                 630                 635                 640 


Leu Tyr Gln Ser Cys Pro Arg Gly Val Val Pro Phe Gln Ala Gly Ser 
                645                 650                 655     


Arg Asn Tyr Glu Leu Ser Phe Gln Gly Met Ile Gln Thr Asn Ile Ala 
            660                 665                 670         


Ser Lys Thr Gln Lys Asp Val Ile Arg Arg Pro Thr Phe Val Pro Gln 
        675                 680                 685             


Trp Tyr Val Gln Gln Met Lys Arg Gly Pro Glu 
    690                 695                 


<210>  2767
<211>  144
<212>  PRT
<213>  homo sapiens

<400>  2767

Met Tyr Ser Glu Ile Gln Arg Glu Arg Ala Asp Ile Gly Gly Leu Met 
1               5                   10                  15      


Ala Arg Pro Glu Tyr Arg Glu Trp Asn Pro Glu Leu Ile Lys Pro Lys 
            20                  25                  30          


Lys Leu Leu Asn Pro Val Lys Ala Ser Arg Ser His Gln Glu Leu His 
        35                  40                  45              


Arg Glu Leu Leu Met Asn His Arg Arg Gly Leu Gly Val Asp Ser Lys 
    50                  55                  60                  


Pro Glu Leu Gln Arg Val Leu Glu His Arg Arg Arg Asn Gln Leu Ile 
65                  70                  75                  80  


Lys Lys Lys Lys Glu Glu Leu Glu Ala Lys Arg Leu Gln Cys Pro Phe 
                85                  90                  95      


Glu Gln Glu Leu Leu Arg Arg Gln Gln Arg Leu Asn Gln Leu Glu Lys 
            100                 105                 110         


Pro Pro Glu Lys Glu Glu Asp His Ala Pro Glu Phe Ile Lys Val Arg 
        115                 120                 125             


Glu Asn Leu Arg Arg Ile Ala Thr Leu Thr Ser Glu Glu Arg Glu Leu 
    130                 135                 140                 


<210>  2768
<211>  394
<212>  PRT
<213>  homo sapiens

<400>  2768

Met Ala Gln Arg Tyr Asp Glu Leu Pro His Tyr Gly Gly Met Asp Gly 
1               5                   10                  15      


Val Gly Val Pro Ala Ser Met Tyr Gly Asp Pro His Ala Pro Arg Pro 
            20                  25                  30          


Ile Pro Pro Val His His Leu Asn His Gly Pro Pro Leu His Ala Thr 
        35                  40                  45              


Gln His Tyr Gly Ala His Ala Pro His Pro Asn Val Met Pro Ala Ser 
    50                  55                  60                  


Met Gly Ser Ala Val Asn Asp Ala Leu Lys Arg Asp Lys Asp Ala Ile 
65                  70                  75                  80  


Tyr Gly His Pro Leu Phe Pro Leu Leu Ala Leu Val Phe Glu Lys Cys 
                85                  90                  95      


Glu Leu Ala Thr Cys Thr Pro Arg Glu Pro Gly Val Ala Gly Gly Asp 
            100                 105                 110         


Val Cys Ser Ser Asp Ser Phe Asn Glu Asp Ile Ala Val Phe Ala Lys 
        115                 120                 125             


Gln Val Arg Ala Glu Lys Pro Leu Phe Ser Ser Asn Pro Glu Leu Asp 
    130                 135                 140                 


Asn Leu Met Ile Gln Ala Ile Gln Val Leu Arg Phe His Leu Leu Glu 
145                 150                 155                 160 


Leu Glu Lys Val His Glu Leu Cys Asp Asn Phe Cys His Arg Tyr Ile 
                165                 170                 175     


Ser Cys Leu Lys Gly Lys Met Pro Ile Asp Leu Val Ile Asp Glu Arg 
            180                 185                 190         


Asp Gly Ser Ser Lys Ser Asp His Glu Glu Leu Ser Gly Ser Ser Thr 
        195                 200                 205             


Asn Leu Ala Asp His Asn Pro Ser Ser Trp Arg Asp His Asp Asp Ala 
    210                 215                 220                 


Thr Ser Thr His Ser Ala Gly Thr Pro Gly Pro Ser Ser Gly Gly His 
225                 230                 235                 240 


Ala Ser Gln Ser Gly Asp Asn Ser Ser Glu Gln Gly Asp Gly Leu Asp 
                245                 250                 255     


Asn Ser Val Ala Ser Pro Gly Thr Gly Asp Asp Asp Asp Pro Asp Lys 
            260                 265                 270         


Asp Lys Lys Arg Gln Lys Lys Arg Gly Ile Phe Pro Lys Val Ala Thr 
        275                 280                 285             


Asn Ile Met Arg Ala Trp Leu Phe Gln His Leu Thr His Pro Tyr Pro 
    290                 295                 300                 


Ser Glu Glu Gln Lys Lys Gln Leu Ala Gln Asp Thr Gly Leu Thr Ile 
305                 310                 315                 320 


Leu Gln Val Asn Asn Trp Phe Ile Asn Ala Arg Arg Arg Ile Val Gln 
                325                 330                 335     


Pro Met Ile Asp Gln Ser Asn Arg Ala Val Ser Gln Gly Ala Ala Tyr 
            340                 345                 350         


Ser Pro Glu Gly Gln Pro Met Gly Ser Phe Val Leu Asp Gly Gln Gln 
        355                 360                 365             


His Met Gly Ile Arg Pro Ala Gly Pro Met Ser Gly Met Gly Met Asn 
    370                 375                 380                 


Met Gly Met Asp Gly Gln Trp His Tyr Met 
385                 390                 


<210>  2769
<211>  470
<212>  PRT
<213>  homo sapiens

<400>  2769

Met Ala Gln Arg Tyr Asp Glu Leu Pro His Tyr Gly Gly Met Asp Gly 
1               5                   10                  15      


Val Gly Val Pro Ala Ser Met Tyr Gly Asp Pro His Ala Pro Arg Pro 
            20                  25                  30          


Ile Pro Pro Val His His Leu Asn His Gly Pro Pro Leu His Ala Thr 
        35                  40                  45              


Gln His Tyr Gly Ala His Ala Pro His Pro Asn Val Met Pro Ala Ser 
    50                  55                  60                  


Met Gly Ser Ala Val Asn Asp Ala Leu Lys Arg Asp Lys Asp Ala Ile 
65                  70                  75                  80  


Tyr Gly His Pro Leu Phe Pro Leu Leu Ala Leu Val Phe Glu Lys Cys 
                85                  90                  95      


Glu Leu Ala Thr Cys Thr Pro Arg Glu Pro Gly Val Ala Gly Gly Asp 
            100                 105                 110         


Val Cys Ser Ser Asp Ser Phe Asn Glu Asp Ile Ala Val Phe Ala Lys 
        115                 120                 125             


Gln Val Arg Ala Glu Lys Pro Leu Phe Ser Ser Asn Pro Glu Leu Asp 
    130                 135                 140                 


Asn Leu Met Ile Gln Ala Ile Gln Val Leu Arg Phe His Leu Leu Glu 
145                 150                 155                 160 


Leu Glu Lys Val His Glu Leu Cys Asp Asn Phe Cys His Arg Tyr Ile 
                165                 170                 175     


Ser Cys Leu Lys Gly Lys Met Pro Ile Asp Leu Val Ile Asp Glu Arg 
            180                 185                 190         


Asp Gly Ser Ser Lys Ser Asp His Glu Glu Leu Ser Gly Ser Ser Thr 
        195                 200                 205             


Asn Leu Ala Asp His Asn Pro Ser Ser Trp Arg Asp His Asp Asp Ala 
    210                 215                 220                 


Thr Ser Thr His Ser Ala Gly Thr Pro Gly Pro Ser Ser Gly Gly His 
225                 230                 235                 240 


Ala Ser Gln Ser Gly Asp Asn Ser Ser Glu Gln Gly Asp Gly Leu Asp 
                245                 250                 255     


Asn Ser Val Ala Ser Pro Gly Thr Gly Asp Asp Asp Asp Pro Asp Lys 
            260                 265                 270         


Asp Lys Lys Arg Gln Lys Lys Arg Gly Ile Phe Pro Lys Val Ala Thr 
        275                 280                 285             


Asn Ile Met Arg Ala Trp Leu Phe Gln His Leu Thr His Pro Tyr Pro 
    290                 295                 300                 


Ser Glu Glu Gln Lys Lys Gln Leu Ala Gln Asp Thr Gly Leu Thr Ile 
305                 310                 315                 320 


Leu Gln Val Asn Asn Trp Phe Ile Asn Ala Arg Arg Arg Ile Val Gln 
                325                 330                 335     


Pro Met Ile Asp Gln Ser Asn Arg Ala Val Ser Gln Gly Ala Ala Tyr 
            340                 345                 350         


Ser Pro Glu Gly Gln Pro Met Gly Ser Phe Val Leu Asp Gly Gln Gln 
        355                 360                 365             


His Met Gly Ile Arg Pro Ala Gly Leu Gln Ser Met Pro Gly Asp Tyr 
    370                 375                 380                 


Val Ser Gln Gly Gly Pro Met Gly Met Ser Met Ala Gln Pro Ser Tyr 
385                 390                 395                 400 


Thr Pro Pro Gln Met Thr Pro His Pro Thr Gln Leu Arg His Gly Pro 
                405                 410                 415     


Pro Met His Ser Tyr Leu Pro Ser His Pro His His Pro Ala Met Met 
            420                 425                 430         


Met His Gly Gly Pro Pro Thr His Pro Gly Met Thr Met Ser Ala Gln 
        435                 440                 445             


Ser Pro Thr Met Leu Asn Ser Val Asp Pro Asn Val Gly Gly Gln Val 
    450                 455                 460                 


Met Asp Ile His Ala Gln 
465                 470 


<210>  2770
<211>  229
<212>  PRT
<213>  homo sapiens

<400>  2770

Met Ala Ala Gln Pro Leu Arg His Arg Ser Arg Cys Ala Thr Pro Pro 
1               5                   10                  15      


Arg Gly Asp Phe Cys Gly Gly Thr Glu Arg Ala Ile Asp Gln Ala Ser 
            20                  25                  30          


Phe Thr Thr Ser Met Glu Trp Asp Thr Gln Val Val Lys Gly Ser Ser 
        35                  40                  45              


Pro Leu Gly Pro Ala Gly Leu Gly Ala Glu Glu Pro Ala Ala Gly Pro 
    50                  55                  60                  


Gln Leu Pro Ser Trp Leu Gln Pro Glu Arg Cys Ala Val Phe Gln Cys 
65                  70                  75                  80  


Ala Gln Cys His Ala Val Leu Ala Asp Ser Val His Leu Ala Trp Asp 
                85                  90                  95      


Leu Ser Arg Ser Leu Gly Ala Val Val Phe Ser Arg Val Thr Asn Asn 
            100                 105                 110         


Val Val Leu Glu Ala Pro Phe Leu Val Gly Ile Glu Gly Ser Leu Lys 
        115                 120                 125             


Gly Ser Thr Tyr Asn Leu Leu Phe Cys Gly Ser Cys Gly Ile Pro Val 
    130                 135                 140                 


Gly Phe His Leu Tyr Ser Thr His Ala Ala Leu Ala Ala Leu Arg Gly 
145                 150                 155                 160 


His Phe Cys Leu Ser Ser Asp Lys Met Val Cys Tyr Leu Leu Lys Thr 
                165                 170                 175     


Lys Ala Ile Val Asn Ala Ser Glu Met Asp Ile Gln Asn Val Pro Leu 
            180                 185                 190         


Ser Glu Lys Ile Ala Glu Leu Lys Glu Lys Ile Val Leu Thr His Asn 
        195                 200                 205             


Arg Leu Lys Ser Leu Met Lys Ile Leu Ser Glu Val Thr Pro Asp Gln 
    210                 215                 220                 


Ser Lys Pro Glu Asn 
225                 


<210>  2771
<211>  440
<212>  PRT
<213>  homo sapiens

<400>  2771

Met Ala Glu Asn Asn Glu Asn Ile Ser Lys Asn Val Asp Val Arg Pro 
1               5                   10                  15      


Lys Thr Ser Arg Ser Arg Ser Ala Asp Arg Lys Asp Gly Tyr Val Trp 
            20                  25                  30          


Ser Gly Lys Lys Leu Ser Trp Ser Lys Lys Ser Glu Ser Tyr Ser Asp 
        35                  40                  45              


Ala Glu Thr Val Asn Gly Ile Glu Lys Thr Glu Val Ser Leu Arg Asn 
    50                  55                  60                  


Gln Glu Arg Lys His Ser Cys Ser Ser Ile Glu Leu Asp Leu Asp His 
65                  70                  75                  80  


Ser Cys Gly His Arg Phe Leu Gly Arg Ser Leu Lys Gln Lys Leu Gln 
                85                  90                  95      


Asp Ala Val Gly Gln Cys Phe Pro Ile Lys Asn Cys Ser Ser Arg His 
            100                 105                 110         


Ser Ser Gly Leu Pro Ser Lys Arg Lys Ile His Ile Ser Glu Leu Met 
        115                 120                 125             


Leu Asp Lys Cys Pro Phe Pro Pro Arg Ser Asp Leu Ala Phe Arg Trp 
    130                 135                 140                 


His Phe Ile Lys Arg His Thr Ala Pro Ile Asn Ser Lys Ser Asp Glu 
145                 150                 155                 160 


Trp Val Ser Thr Asp Leu Ser Gln Thr Glu Leu Arg Asp Gly Gln Leu 
                165                 170                 175     


Lys Arg Arg Asn Met Glu Glu Asn Ile Asn Cys Phe Ser His Thr Asn 
            180                 185                 190         


Val Gln Pro Cys Val Ile Thr Thr Asp Asn Ala Leu Cys Arg Glu Gly 
        195                 200                 205             


Pro Met Thr Gly Ser Val Met Asn Leu Val Ser Asn Asn Ser Ile Glu 
    210                 215                 220                 


Asp Ser Asp Met Asp Ser Asp Asp Glu Ile Leu Thr Leu Cys Thr Ser 
225                 230                 235                 240 


Ser Arg Lys Arg Asn Lys Pro Lys Trp Asp Leu Asp Asp Glu Ile Leu 
                245                 250                 255     


Gln Leu Glu Thr Pro Pro Lys Tyr His Thr Gln Ile Asp Tyr Val His 
            260                 265                 270         


Cys Leu Val Pro Asp Leu Leu Gln Ile Asn Asn Asn Pro Cys Tyr Trp 
        275                 280                 285             


Gly Val Met Asp Lys Tyr Ala Ala Glu Ala Leu Leu Glu Gly Lys Pro 
    290                 295                 300                 


Glu Gly Thr Phe Leu Leu Arg Asp Ser Ala Gln Glu Asp Tyr Leu Phe 
305                 310                 315                 320 


Ser Val Ser Phe Arg Arg Tyr Ser Arg Ser Leu His Ala Arg Ile Glu 
                325                 330                 335     


Gln Trp Asn His Asn Phe Ser Phe Asp Ala His Asp Pro Cys Val Phe 
            340                 345                 350         


His Ser Pro Asp Ile Thr Gly Leu Leu Glu His Tyr Lys Asp Pro Ser 
        355                 360                 365             


Ala Cys Met Phe Phe Glu Pro Leu Leu Ser Thr Pro Leu Ile Arg Thr 
    370                 375                 380                 


Phe Pro Phe Ser Leu Gln His Ile Cys Arg Thr Val Ile Cys Asn Cys 
385                 390                 395                 400 


Thr Thr Tyr Asp Gly Ile Asp Ala Leu Pro Ile Pro Ser Ser Met Lys 
                405                 410                 415     


Leu Tyr Leu Lys Glu Tyr His Tyr Lys Ser Lys Val Arg Val Leu Arg 
            420                 425                 430         


Ile Asp Ala Pro Glu Gln Gln Cys 
        435                 440 


<210>  2772
<211>  848
<212>  PRT
<213>  homo sapiens

<400>  2772

Met Gln Ala Glu Ala Ala Asp Trp Phe Ser Ser Met Pro Phe Gln Lys 
1               5                   10                  15      


His Val Tyr Tyr Pro Leu Ala Ser Gly Pro Glu Gly Pro Asp Val Ala 
            20                  25                  30          


Val Ala Ala Ala Ala Ala Gly Ala Ala Ser Met Ala Cys Ala Pro Pro 
        35                  40                  45              


Ser Ala Ala Ser Gly Pro Leu Pro Phe Phe Gln Phe Arg Pro Arg Leu 
    50                  55                  60                  


Glu Ser Val Asp Trp Arg Arg Leu Ser Ala Ile Asp Val Asp Lys Val 
65                  70                  75                  80  


Ala Gly Ala Val Asp Val Leu Thr Leu Gln Glu Asn Ile Met Asn Ile 
                85                  90                  95      


Thr Phe Cys Lys Leu Glu Asp Glu Lys Cys Pro His Cys Gln Ser Gly 
            100                 105                 110         


Val Asp Pro Val Leu Leu Lys Leu Ile Arg Leu Ala Gln Phe Thr Ile 
        115                 120                 125             


Glu Tyr Leu Leu His Ser Gln Glu Phe Leu Thr Ser Gln Leu His Thr 
    130                 135                 140                 


Leu Glu Glu Arg Leu Arg Leu Ser His Cys Asp Gly Glu Gln Ser Lys 
145                 150                 155                 160 


Lys Leu Leu Thr Lys Gln Ala Gly Glu Ile Lys Thr Leu Lys Glu Glu 
                165                 170                 175     


Cys Lys Arg Arg Lys Lys Met Ile Ser Thr Gln Gln Leu Met Ile Glu 
            180                 185                 190         


Ala Lys Ala Asn Tyr Tyr Gln Cys His Phe Cys Asp Lys Ala Phe Met 
        195                 200                 205             


Asn Gln Ala Phe Leu Gln Ser His Ile Gln Arg Arg His Thr Glu Glu 
    210                 215                 220                 


Asn Ser His Phe Glu Tyr Gln Lys Asn Ala Gln Ile Glu Lys Leu Arg 
225                 230                 235                 240 


Ser Glu Ile Val Val Leu Lys Glu Glu Leu Gln Leu Thr Arg Ser Glu 
                245                 250                 255     


Leu Glu Ala Ala His His Ala Ser Ala Val Arg Phe Ser Lys Glu Tyr 
            260                 265                 270         


Glu Met Gln Lys Thr Lys Glu Glu Asp Phe Leu Lys Leu Phe Asp Arg 
        275                 280                 285             


Trp Lys Glu Glu Glu Lys Glu Lys Leu Val Asp Glu Met Glu Lys Val 
    290                 295                 300                 


Lys Glu Met Phe Met Lys Glu Phe Lys Glu Leu Thr Ser Lys Asn Ser 
305                 310                 315                 320 


Ala Leu Glu Tyr Gln Leu Ser Glu Ile Gln Lys Ser Asn Met Gln Ile 
                325                 330                 335     


Lys Ser Asn Ile Gly Thr Leu Lys Asp Ala His Glu Phe Lys Glu Asp 
            340                 345                 350         


Arg Ser Pro Tyr Pro Gln Asp Phe His Asn Val Met Gln Leu Leu Asp 
        355                 360                 365             


Ser Gln Glu Ser Lys Trp Thr Ala Arg Val Gln Ala Ile His Gln Glu 
    370                 375                 380                 


His Lys Lys Glu Lys Gly Arg Leu Leu Ser His Ile Glu Lys Leu Arg 
385                 390                 395                 400 


Thr Ser Met Ile Asp Asp Leu Asn Ala Ser Asn Val Phe Tyr Lys Lys 
                405                 410                 415     


Arg Ile Glu Glu Leu Gly Gln Arg Leu Gln Glu Gln Asn Glu Leu Ile 
            420                 425                 430         


Ile Thr Gln Arg Gln Gln Ile Lys Asp Phe Thr Cys Asn Pro Leu Asn 
        435                 440                 445             


Ser Ile Ser Glu Pro Lys Val Asn Ala Pro Ala Leu His Thr Leu Glu 
    450                 455                 460                 


Thr Lys Ser Ser Leu Pro Met Val His Glu Gln Ala Phe Ser Ser His 
465                 470                 475                 480 


Ile Leu Glu Pro Ile Glu Glu Leu Ser Glu Glu Glu Lys Gly Arg Glu 
                485                 490                 495     


Asn Glu Gln Lys Leu Asn Asn Asn Lys Met His Leu Arg Lys Ala Leu 
            500                 505                 510         


Lys Ser Asn Ser Ser Leu Thr Lys Gly Leu Arg Thr Met Val Glu Gln 
        515                 520                 525             


Asn Leu Met Glu Lys Leu Glu Thr Leu Gly Ile Asn Ala Asp Ile Arg 
    530                 535                 540                 


Gly Ile Ser Ser Asp Gln Leu His Arg Val Leu Lys Ser Val Glu Ser 
545                 550                 555                 560 


Glu Arg His Lys Gln Glu Arg Glu Ile Pro Asn Phe His Gln Ile Arg 
                565                 570                 575     


Glu Phe Leu Glu His Gln Val Ser Cys Lys Ile Glu Glu Lys Ala Leu 
            580                 585                 590         


Leu Ser Ser Asp Gln Cys Ser Val Ser Gln Met Asp Thr Leu Ser Thr 
        595                 600                 605             


Gly Glu Val Pro Lys Met Ile Gln Leu Pro Ser Lys Asn Arg Gln Leu 
    610                 615                 620                 


Ile Arg Gln Lys Ala Val Ser Thr Asp Arg Thr Ser Val Pro Lys Ile 
625                 630                 635                 640 


Lys Lys Asn Val Met Glu Asp Pro Phe Pro Arg Lys Ser Ser Thr Ile 
                645                 650                 655     


Thr Thr Pro Pro Phe Ser Ser Glu Glu Glu Gln Glu Asp Asp Asp Leu 
            660                 665                 670         


Ile Arg Ala Tyr Ala Ser Pro Gly Pro Leu Pro Val Pro Pro Pro Gln 
        675                 680                 685             


Asn Lys Gly Ser Phe Gly Lys Asn Thr Val Lys Ser Asp Ala Asp Gly 
    690                 695                 700                 


Thr Glu Gly Ser Glu Ile Glu Asp Thr Asp Asp Ser Pro Lys Pro Ala 
705                 710                 715                 720 


Gly Val Ala Val Lys Thr Pro Thr Glu Lys Val Glu Lys Met Phe Pro 
                725                 730                 735     


His Arg Lys Asn Val Asn Lys Pro Val Gly Gly Thr Asn Val Pro Glu 
            740                 745                 750         


Met Phe Ile Lys Lys Glu Glu Leu Gln Glu Leu Lys Cys Ala Asp Val 
        755                 760                 765             


Glu Asp Glu Asp Trp Asp Ile Ser Ser Leu Glu Glu Glu Ile Ser Leu 
    770                 775                 780                 


Gly Lys Lys Ser Gly Lys Glu Gln Lys Glu Pro Pro Pro Ala Lys Asn 
785                 790                 795                 800 


Glu Pro His Phe Ala His Val Leu Asn Ala Trp Gly Ala Phe Asn Pro 
                805                 810                 815     


Lys Gly Pro Lys Gly Glu Gly Leu Gln Glu Asn Glu Ser Ser Thr Leu 
            820                 825                 830         


Lys Ser Ser Leu Val Thr Val Thr Asp Trp Ser Asp Thr Ser Asp Val 
        835                 840                 845             


<210>  2773
<211>  1606
<212>  PRT
<213>  homo sapiens

<400>  2773

Met Val Val Phe Ile Asn Ala Lys Ile Lys Ser Leu Ile Lys Leu Phe 
1               5                   10                  15      


Lys Lys Lys Thr Val Ser Asn Leu Asp Glu Glu Ser Arg Trp Thr Val 
            20                  25                  30          


His Tyr Thr Ala Pro Trp His Gln Gln Glu Asn Val Phe Leu Pro Thr 
        35                  40                  45              


Thr Arg Pro Pro Cys Val Glu Asp Leu His Arg Gln Ala Lys Leu Asn 
    50                  55                  60                  


Leu Lys Ser Val Leu Arg Glu Cys Asp Lys Leu Arg His Asp Gly Tyr 
65                  70                  75                  80  


Arg Ser Ser Gln Tyr Tyr Ser Gln Gly Pro Thr Phe Ala Ala Asn Ala 
                85                  90                  95      


Ser Pro Phe Cys Asp Asp Tyr Gln Asp Glu Asp Glu Glu Thr Asp Gln 
            100                 105                 110         


Lys Cys Ser Leu Ser Ser Ser Glu Glu Glu Arg Phe Ile Ser Ile Arg 
        115                 120                 125             


Arg Pro Lys Thr Pro Ala Ser Ser Asp Phe Ser Asp Leu Asn Thr Gln 
    130                 135                 140                 


Thr Asn Trp Thr Lys Ser Leu Pro Leu Pro Thr Pro Glu Glu Lys Met 
145                 150                 155                 160 


Arg Gln Gln Ala Gln Thr Val Gln Ala Asp Val Val Pro Ile Asn Ile 
                165                 170                 175     


Thr Gly Glu Asn Phe Asp Arg Gln Ala Ser Leu Arg Arg Ser Leu Ile 
            180                 185                 190         


Tyr Thr Asp Thr Leu Val Arg Arg Pro Lys Lys Val Lys Arg Arg Lys 
        195                 200                 205             


Thr Ile Thr Gly Val Pro Asp Asn Ile Gln Lys Glu Leu Ala Ser Gly 
    210                 215                 220                 


Thr Gly Gln Asp Asp Ala Asp Gly His Ser Val Tyr Thr Pro Asp His 
225                 230                 235                 240 


Tyr Ser Thr Leu Gly Arg Phe Asn Ser Cys Arg Ser Ala Gly Gln Arg 
                245                 250                 255     


Ser Glu Thr Arg Asp Ser Ser Cys Gln Thr Glu Asp Val Lys Val Val 
            260                 265                 270         


Pro Pro Ser Met Arg Arg Ile Arg Ala Gln Lys Gly Gln Gly Ile Ala 
        275                 280                 285             


Ala Gln Met Gly His Phe Ser Gly Ser Ser Gly Asn Met Ser Val Leu 
    290                 295                 300                 


Ser Asp Ser Ala Gly Ile Val Phe Pro Ser Arg Leu Asp Ser Asp Ala 
305                 310                 315                 320 


Gly Phe His Ser Leu Pro Arg Ser Gly Ala Arg Ala Asn Ile Gln Ser 
                325                 330                 335     


Leu Glu Pro Arg Leu Gly Ala Leu Gly Pro Ala Gly Asp Met Asn Gly 
            340                 345                 350         


Thr Phe Leu Tyr Gln Arg Gly His Pro Gln Ala Asp Glu Asn Leu Gly 
        355                 360                 365             


His Leu Gly Gly Ala Ser Gly Thr Gly Thr Leu Leu Arg Pro Lys Ser 
    370                 375                 380                 


Gln Glu Leu Arg His Phe Glu Ser Glu Asn Ile Met Ser Pro Ala Cys 
385                 390                 395                 400 


Val Val Ser Pro His Ala Thr Tyr Ser Thr Ser Ile Ile Pro Asn Ala 
                405                 410                 415     


Thr Leu Ser Ser Ser Ser Glu Val Ile Ala Ile Pro Thr Ala Gln Ser 
            420                 425                 430         


Ala Gly Gln Arg Glu Ser Lys Ser Ser Gly Ser Ser His Ala Arg Ile 
        435                 440                 445             


Lys Ser Arg Asp His Leu Ile Ser Arg His Ala Val Lys Gly Asp Pro 
    450                 455                 460                 


Gln Ser Pro Gly Arg His Trp Asn Glu Gly His Ala Thr Ile Leu Ser 
465                 470                 475                 480 


Gln Asp Leu Asp Pro His Ser Pro Gly Glu Pro Ala Leu Leu Ser Leu 
                485                 490                 495     


Cys Asp Ser Ala Val Pro Leu Asn Ala Pro Ala Asn Arg Glu Asn Gly 
            500                 505                 510         


Ser Gln Ala Met Pro Tyr Asn Cys Arg Asn Asn Leu Ala Phe Pro Ala 
        515                 520                 525             


His Pro Gln Asp Val Asp Gly Lys Ser Glu Ser Ser Tyr Ser Gly Gly 
    530                 535                 540                 


Gly Gly His Ser Ser Ser Glu Pro Trp Glu Tyr Lys Ser Ser Gly Asn 
545                 550                 555                 560 


Gly Arg Ala Ser Pro Leu Lys Pro His Leu Ala Thr Pro Gly Tyr Ser 
                565                 570                 575     


Thr Pro Thr Ser Asn Met Ser Ser Cys Ser Leu Asp Gln Thr Ser Asn 
            580                 585                 590         


Lys Glu Asp Ala Gly Ser Leu Tyr Ser Glu Asp His Asp Gly Tyr Cys 
        595                 600                 605             


Ala Ser Val His Thr Asp Ser Gly His Gly Ser Gly Asn Leu Cys Asn 
    610                 615                 620                 


Ser Ser Asp Gly Phe Gly Asn Pro Arg His Ser Val Ile Asn Val Phe 
625                 630                 635                 640 


Val Gly Arg Ala Gln Lys Asn Gln Gly Asp Arg Ser Asn Tyr Gln Asp 
                645                 650                 655     


Lys Ser Leu Ser Arg Asn Ile Ser Leu Lys Lys Ala Lys Lys Pro Pro 
            660                 665                 670         


Leu Pro Pro Ser Arg Thr Asp Ser Leu Arg Arg Ile Pro Lys Lys Ser 
        675                 680                 685             


Ser Gln Cys Asn Gly Gln Val Leu Asn Glu Ser Leu Ile Ala Thr Leu 
    690                 695                 700                 


Gln His Ser Leu Gln Leu Ser Leu Pro Gly Lys Ser Gly Ser Ser Pro 
705                 710                 715                 720 


Ser Gln Ser Pro Cys Ser Asp Leu Glu Glu Pro Trp Leu Pro Arg Ser 
                725                 730                 735     


Arg Ser Gln Ser Thr Val Ser Ala Gly Ser Ser Met Thr Ser Ala Thr 
            740                 745                 750         


Thr Pro Asn Val Tyr Ser Leu Cys Gly Ala Thr Pro Ser Gln Ser Asp 
        755                 760                 765             


Thr Ser Ser Val Lys Ser Glu Tyr Thr Asp Pro Trp Gly Tyr Tyr Ile 
    770                 775                 780                 


Asp Tyr Thr Gly Met Gln Glu Asp Pro Gly Asn Pro Ala Gly Gly Cys 
785                 790                 795                 800 


Ser Thr Ser Ser Gly Val Pro Thr Gly Asn Gly Pro Val Arg His Val 
                805                 810                 815     


Gln Glu Gly Ser Arg Ala Thr Met Pro Gln Val Pro Gly Gly Ser Val 
            820                 825                 830         


Lys Pro Lys Ile Met Ser Pro Glu Lys Ser His Arg Val Ile Ser Pro 
        835                 840                 845             


Ser Ser Gly Tyr Ser Ser Gln Ser Asn Thr Pro Thr Ala Leu Thr Pro 
    850                 855                 860                 


Val Pro Val Phe Leu Lys Ser Val Ser Pro Ala Asn Gly Lys Gly Lys 
865                 870                 875                 880 


Pro Lys Pro Lys Val Pro Glu Arg Lys Ser Ser Leu Ile Ser Ser Val 
                885                 890                 895     


Ser Ile Ser Ser Ser Ser Thr Ser Leu Ser Ser Ser Thr Ser Thr Glu 
            900                 905                 910         


Gly Ser Gly Thr Met Lys Lys Leu Asp Pro Ala Val Gly Ser Pro Pro 
        915                 920                 925             


Ala Pro Pro Pro Pro Pro Val Pro Ser Pro Pro Phe Pro Cys Pro Ala 
    930                 935                 940                 


Asp Arg Ser Pro Phe Leu Pro Pro Pro Pro Pro Val Thr Asp Cys Ser 
945                 950                 955                 960 


Gln Gly Ser Pro Leu Pro His Ser Pro Val Phe Pro Pro Pro Pro Pro 
                965                 970                 975     


Glu Ala Leu Ile Pro Phe Cys Ser Pro Pro Asp Trp Cys Leu Ser Pro 
            980                 985                 990         


Pro Arg Pro Ala Leu Ser Pro Ile  Leu Pro Asp Ser Pro  Val Ser Leu 
        995                 1000                 1005             


Pro Leu  Pro Pro Pro Leu Leu  Pro Ser Ser Glu Pro  Pro Pro Ala 
    1010                 1015                 1020             


Pro Pro  Leu Asp Pro Lys Phe  Met Lys Asp Thr Arg  Pro Pro Phe 
    1025                 1030                 1035             


Thr Asn  Ser Gly Gln Pro Glu  Ser Ser Arg Gly Ser  Leu Arg Pro 
    1040                 1045                 1050             


Pro Ser  Thr Lys Glu Glu Thr  Ser Arg Pro Pro Met  Pro Leu Ile 
    1055                 1060                 1065             


Thr Thr  Glu Ala Leu Gln Met  Val Gln Leu Arg Pro  Val Arg Lys 
    1070                 1075                 1080             


Asn Ser  Gly Ala Glu Ala Ala  Gln Leu Ser Glu Arg  Thr Ala Gln 
    1085                 1090                 1095             


Glu Gln  Arg Thr Pro Val Ala  Pro Gln Tyr His Leu  Lys Pro Ser 
    1100                 1105                 1110             


Ala Phe  Leu Lys Ser Arg Asn  Ser Thr Asn Glu Met  Glu Ser Glu 
    1115                 1120                 1125             


Ser Gln  Pro Ala Ser Val Thr  Ser Ser Leu Pro Thr  Pro Ala Lys 
    1130                 1135                 1140             


Ser Ser  Ser Gln Gly Asp His  Gly Ser Ala Ala Glu  Arg Gly Gly 
    1145                 1150                 1155             


Pro Val  Ser Arg Ser Pro Gly  Ala Pro Ser Ala Gly  Glu Ala Glu 
    1160                 1165                 1170             


Ala Arg  Pro Ser Pro Ser Thr  Thr Pro Leu Pro Asp  Ser Ser Pro 
    1175                 1180                 1185             


Ser Arg  Lys Pro Pro Pro Ile  Ser Lys Lys Pro Lys  Leu Phe Leu 
    1190                 1195                 1200             


Val Val  Pro Pro Pro Gln Lys  Asp Phe Ala Val Glu  Pro Ala Glu 
    1205                 1210                 1215             


Asn Val  Ser Glu Ala Leu Arg  Ala Val Pro Ser Pro  Thr Thr Gly 
    1220                 1225                 1230             


Glu Glu  Gly Ser Val His Ser  Arg Glu Ala Lys Glu  Ser Ser Ala 
    1235                 1240                 1245             


Ala Gln  Ala Gly Ser His Ala  Thr His Pro Gly Thr  Ser Val Leu 
    1250                 1255                 1260             


Glu Gly  Gly Ala Ala Gly Ser  Met Ser Pro Ser Arg  Val Glu Ala 
    1265                 1270                 1275             


Asn Val  Pro Met Val Gln Pro  Asp Val Ser Pro Ala  Pro Lys Gln 
    1280                 1285                 1290             


Glu Glu  Pro Ala Glu Asn Ser  Ala Asp Thr Gly Gly  Asp Gly Glu 
    1295                 1300                 1305             


Ser Cys  Leu Ser Gln Gln Asp  Gly Ala Ala Gly Val  Pro Glu Thr 
    1310                 1315                 1320             


Asn Ala  Ala Gly Ser Ser Ser  Glu Ala Cys Asp Phe  Leu Lys Glu 
    1325                 1330                 1335             


Asp Gly  Asn Asp Glu Val Met  Thr Pro Ser Arg Pro  Arg Thr Thr 
    1340                 1345                 1350             


Glu Asp  Leu Phe Ala Ala Ile  His Arg Ser Lys Arg  Lys Val Leu 
    1355                 1360                 1365             


Gly Arg  Arg Asp Ser Asp Asp  Asp His Ser Arg Asn  His Ser Pro 
    1370                 1375                 1380             


Ser Pro  Pro Val Thr Pro Thr  Gly Ala Ala Pro Ser  Leu Ala Ser 
    1385                 1390                 1395             


Pro Lys  Gln Val Gly Ser Ile  Gln Arg Ser Ile Arg  Lys Ser Ser 
    1400                 1405                 1410             


Thr Ser  Ser Asp Asn Phe Lys  Ala Leu Leu Leu Lys  Lys Gly Ser 
    1415                 1420                 1425             


Arg Ser  Asp Thr Ser Ala Arg  Met Ser Ala Ala Glu  Met Leu Lys 
    1430                 1435                 1440             


Asn Thr  Asp Pro Arg Phe Gln  Arg Ser Arg Ser Glu  Pro Ser Pro 
    1445                 1450                 1455             


Asp Ala  Pro Glu Ser Pro Ser  Ser Cys Ser Pro Ser  Lys Asn Arg 
    1460                 1465                 1470             


Arg Ala  Gln Glu Glu Trp Ala  Lys Asn Glu Gly Leu  Met Pro Arg 
    1475                 1480                 1485             


Ser Leu  Ser Phe Ser Gly Pro  Arg Tyr Gly Arg Ser  Arg Thr Pro 
    1490                 1495                 1500             


Pro Ser  Ala Ala Ser Ser Arg  Tyr Ser Met Arg Asn  Arg Ile Gln 
    1505                 1510                 1515             


Ser Ser  Pro Met Thr Val Ile  Ser Glu Gly Glu Gly  Glu Ala Val 
    1520                 1525                 1530             


Glu Pro  Val Asp Ser Ile Ala  Arg Gly Ala Leu Gly  Ala Ala Glu 
    1535                 1540                 1545             


Gly Cys  Ser Leu Asp Gly Leu  Ala Arg Glu Glu Met  Asp Glu Gly 
    1550                 1555                 1560             


Gly Leu  Leu Cys Gly Glu Gly  Pro Ala Ala Ser Leu  Gln Pro Gln 
    1565                 1570                 1575             


Ala Pro  Gly Pro Val Asp Gly  Thr Ala Ser Ala Glu  Gly Arg Glu 
    1580                 1585                 1590             


Pro Ser  Pro Gln Cys Gly Gly  Ser Leu Ser Glu Glu  Ser 
    1595                 1600                 1605     


<210>  2774
<211>  406
<212>  PRT
<213>  homo sapiens

<400>  2774

Met Val His Cys Ala Gly Cys Lys Arg Pro Ile Leu Asp Arg Phe Leu 
1               5                   10                  15      


Leu Asn Val Leu Asp Arg Ala Trp His Val Lys Cys Val Gln Cys Cys 
            20                  25                  30          


Glu Cys Lys Cys Asn Leu Thr Glu Lys Cys Phe Ser Arg Glu Gly Lys 
        35                  40                  45              


Leu Tyr Cys Lys Asn Asp Phe Phe Arg Cys Phe Gly Thr Lys Cys Ala 
    50                  55                  60                  


Gly Cys Ala Gln Gly Ile Ser Pro Ser Asp Leu Val Arg Arg Ala Arg 
65                  70                  75                  80  


Ser Lys Val Phe His Leu Asn Cys Phe Thr Cys Met Met Cys Asn Lys 
                85                  90                  95      


Gln Leu Ser Thr Gly Glu Glu Leu Tyr Ile Ile Asp Glu Asn Lys Phe 
            100                 105                 110         


Val Cys Lys Glu Asp Tyr Leu Ser Asn Ser Ser Val Ala Lys Glu Asn 
        115                 120                 125             


Ser Leu His Ser Ala Thr Thr Gly Ser Asp Pro Ser Leu Ser Pro Asp 
    130                 135                 140                 


Ser Gln Asp Pro Ser Gln Asp Asp Ala Lys Asp Ser Glu Ser Ala Asn 
145                 150                 155                 160 


Val Ser Asp Lys Glu Ala Gly Ser Asn Glu Asn Asp Asp Gln Asn Leu 
                165                 170                 175     


Gly Ala Lys Arg Arg Gly Pro Arg Thr Thr Ile Lys Ala Lys Gln Leu 
            180                 185                 190         


Glu Thr Leu Lys Ala Ala Phe Ala Ala Thr Pro Lys Pro Thr Arg His 
        195                 200                 205             


Ile Arg Glu Gln Leu Ala Gln Glu Thr Gly Leu Asn Met Arg Val Ile 
    210                 215                 220                 


Gln Val Trp Phe Gln Asn Arg Arg Ser Lys Glu Arg Arg Met Lys Gln 
225                 230                 235                 240 


Leu Ser Ala Leu Gly Ala Arg Arg His Ala Phe Phe Arg Ser Pro Arg 
                245                 250                 255     


Arg Met Arg Pro Leu Val Asp Arg Leu Glu Pro Gly Glu Leu Ile Pro 
            260                 265                 270         


Asn Gly Pro Phe Ser Phe Tyr Gly Asp Tyr Gln Ser Glu Tyr Tyr Gly 
        275                 280                 285             


Pro Gly Gly Asn Tyr Asp Phe Phe Pro Gln Gly Pro Pro Ser Ser Gln 
    290                 295                 300                 


Ala Gln Thr Pro Val Asp Leu Pro Phe Val Pro Ser Ser Gly Pro Ser 
305                 310                 315                 320 


Gly Thr Pro Leu Gly Gly Leu Glu His Pro Leu Pro Gly His His Pro 
                325                 330                 335     


Ser Ser Glu Ala Gln Arg Phe Thr Asp Ile Leu Ala His Pro Pro Gly 
            340                 345                 350         


Asp Ser Pro Ser Pro Glu Pro Ser Leu Pro Gly Pro Leu His Ser Met 
        355                 360                 365             


Ser Ala Glu Val Phe Gly Pro Ser Pro Pro Phe Ser Ser Leu Ser Val 
    370                 375                 380                 


Asn Gly Gly Ala Ser Tyr Gly Asn His Leu Ser His Pro Pro Glu Met 
385                 390                 395                 400 


Asn Glu Ala Ala Val Trp 
                405     


<210>  2775
<211>  336
<212>  PRT
<213>  homo sapiens

<400>  2775

Met Ser Glu Glu Gln Phe Gly Gly Asp Gly Ala Ala Ala Ala Ala Thr 
1               5                   10                  15      


Ala Ala Val Gly Gly Ser Ala Gly Glu Gln Glu Gly Ala Met Val Ala 
            20                  25                  30          


Ala Thr Gln Gly Ala Ala Ala Ala Ala Gly Ser Gly Ala Gly Thr Gly 
        35                  40                  45              


Gly Gly Thr Ala Ser Gly Gly Thr Glu Gly Gly Ser Ala Glu Ser Glu 
    50                  55                  60                  


Gly Ala Lys Ile Asp Ala Ser Lys Asn Glu Glu Asp Glu Gly Lys Met 
65                  70                  75                  80  


Phe Ile Gly Gly Leu Ser Trp Asp Thr Thr Lys Lys Asp Leu Lys Asp 
                85                  90                  95      


Tyr Phe Ser Lys Phe Gly Glu Val Val Asp Cys Thr Leu Lys Leu Asp 
            100                 105                 110         


Pro Ile Thr Gly Arg Ser Arg Gly Phe Gly Phe Val Leu Phe Lys Glu 
        115                 120                 125             


Ser Glu Ser Val Asp Lys Val Met Asp Gln Lys Glu His Lys Leu Asn 
    130                 135                 140                 


Gly Lys Val Ile Asp Pro Lys Arg Ala Lys Ala Met Lys Thr Lys Glu 
145                 150                 155                 160 


Pro Val Lys Lys Ile Phe Val Gly Gly Leu Ser Pro Asp Thr Pro Glu 
                165                 170                 175     


Glu Lys Ile Arg Glu Tyr Phe Gly Gly Phe Gly Glu Val Glu Ser Ile 
            180                 185                 190         


Glu Leu Pro Met Asp Asn Lys Thr Asn Lys Arg Arg Gly Phe Cys Phe 
        195                 200                 205             


Ile Thr Phe Lys Glu Glu Glu Pro Val Lys Lys Ile Met Glu Lys Lys 
    210                 215                 220                 


Tyr His Asn Val Gly Leu Ser Lys Cys Glu Ile Lys Val Ala Met Ser 
225                 230                 235                 240 


Lys Glu Gln Tyr Gln Gln Gln Gln Gln Trp Gly Ser Arg Gly Gly Phe 
                245                 250                 255     


Ala Gly Arg Ala Arg Gly Arg Gly Gly Gly Pro Ser Gln Asn Trp Asn 
            260                 265                 270         


Gln Gly Tyr Ser Asn Tyr Trp Asn Gln Gly Tyr Gly Asn Tyr Gly Tyr 
        275                 280                 285             


Asn Ser Gln Gly Tyr Gly Gly Tyr Gly Gly Tyr Asp Tyr Thr Gly Tyr 
    290                 295                 300                 


Asn Asn Tyr Tyr Gly Tyr Gly Asp Tyr Ser Asn Gln Gln Ser Gly Tyr 
305                 310                 315                 320 


Gly Lys Val Ser Arg Arg Gly Gly His Gln Asn Ser Tyr Lys Pro Tyr 
                325                 330                 335     


<210>  2776
<211>  474
<212>  PRT
<213>  homo sapiens

<400>  2776

Met Ala Leu Ala Pro Glu Arg Ala Ala Pro Arg Val Leu Phe Gly Glu 
1               5                   10                  15      


Trp Leu Leu Gly Glu Ile Ser Ser Gly Cys Tyr Glu Gly Leu Gln Trp 
            20                  25                  30          


Leu Asp Glu Ala Arg Thr Cys Phe Arg Val Pro Trp Lys His Phe Ala 
        35                  40                  45              


Arg Lys Asp Leu Ser Glu Ala Asp Ala Arg Ile Phe Lys Ala Trp Ala 
    50                  55                  60                  


Val Ala Arg Gly Arg Trp Pro Pro Ser Ser Arg Gly Gly Gly Pro Pro 
65                  70                  75                  80  


Pro Glu Ala Glu Thr Ala Glu Arg Ala Gly Trp Lys Thr Asn Phe Arg 
                85                  90                  95      


Cys Ala Leu Arg Ser Thr Arg Arg Phe Val Met Leu Arg Asp Asn Ser 
            100                 105                 110         


Gly Asp Pro Ala Asp Pro His Lys Val Tyr Ala Leu Ser Arg Glu Leu 
        115                 120                 125             


Cys Trp Arg Glu Gly Pro Gly Thr Asp Gln Thr Glu Ala Glu Ala Pro 
    130                 135                 140                 


Ala Ala Val Pro Pro Pro Gln Gly Gly Pro Pro Gly Pro Phe Leu Ala 
145                 150                 155                 160 


His Thr His Ala Gly Leu Gln Ala Pro Gly Pro Leu Pro Ala Pro Ala 
                165                 170                 175     


Gly Asp Lys Gly Asp Leu Leu Leu Gln Ala Val Gln Gln Ser Cys Leu 
            180                 185                 190         


Ala Asp His Leu Leu Thr Ala Ser Trp Gly Ala Asp Pro Val Pro Thr 
        195                 200                 205             


Lys Ala Pro Gly Glu Gly Gln Glu Gly Leu Pro Leu Thr Gly Ala Cys 
    210                 215                 220                 


Ala Gly Gly Glu Ala Ala Ala Pro Glu Ser Pro His Gln Ala Glu Pro 
225                 230                 235                 240 


Tyr Leu Ser Pro Ser Pro Ser Ala Cys Thr Ala Val Gln Glu Pro Ser 
                245                 250                 255     


Pro Gly Ala Leu Asp Val Thr Ile Met Tyr Lys Gly Arg Thr Val Leu 
            260                 265                 270         


Gln Lys Val Val Gly His Pro Ser Cys Thr Phe Leu Tyr Gly Pro Pro 
        275                 280                 285             


Asp Pro Ala Val Arg Ala Thr Asp Pro Gln Gln Val Ala Phe Pro Ser 
    290                 295                 300                 


Pro Ala Glu Leu Pro Asp Gln Lys Gln Leu Arg Tyr Thr Glu Glu Leu 
305                 310                 315                 320 


Leu Arg His Val Ala Pro Gly Leu His Leu Glu Leu Arg Gly Pro Gln 
                325                 330                 335     


Leu Trp Ala Arg Arg Met Gly Lys Cys Lys Val Tyr Trp Glu Val Gly 
            340                 345                 350         


Gly Pro Pro Gly Ser Ala Ser Pro Ser Thr Pro Ala Cys Leu Leu Pro 
        355                 360                 365             


Arg Asn Cys Asp Thr Pro Ile Phe Asp Phe Arg Val Phe Phe Gln Glu 
    370                 375                 380                 


Leu Val Glu Phe Arg Ala Arg Gln Arg Arg Gly Ser Pro Arg Tyr Thr 
385                 390                 395                 400 


Ile Tyr Leu Gly Phe Gly Gln Asp Leu Ser Ala Gly Arg Pro Lys Glu 
                405                 410                 415     


Lys Ser Leu Val Leu Val Lys Leu Glu Pro Trp Leu Cys Arg Val His 
            420                 425                 430         


Leu Glu Gly Thr Gln Arg Glu Gly Val Ser Ser Leu Asp Ser Ser Ser 
        435                 440                 445             


Leu Ser Leu Cys Leu Ser Ser Ala Asn Ser Leu Tyr Asp Asp Ile Glu 
    450                 455                 460                 


Cys Phe Leu Met Glu Leu Glu Gln Pro Ala 
465                 470                 


<210>  2777
<211>  516
<212>  PRT
<213>  homo sapiens

<400>  2777

Met Pro Val Pro Glu Arg Pro Ala Ala Gly Pro Asp Ser Pro Arg Pro 
1               5                   10                  15      


Gly Thr Arg Arg Ala Ala Pro Arg Val Leu Phe Gly Glu Trp Leu Leu 
            20                  25                  30          


Gly Glu Ile Ser Ser Gly Cys Tyr Glu Gly Leu Gln Trp Leu Asp Glu 
        35                  40                  45              


Ala Arg Thr Cys Phe Arg Val Pro Trp Lys His Phe Ala Arg Lys Asp 
    50                  55                  60                  


Leu Ser Glu Ala Asp Ala Arg Ile Phe Lys Ala Trp Ala Val Ala Arg 
65                  70                  75                  80  


Gly Arg Trp Pro Pro Ser Ser Arg Gly Gly Gly Pro Pro Pro Glu Ala 
                85                  90                  95      


Glu Thr Ala Glu Arg Ala Gly Trp Lys Thr Asn Phe Arg Cys Ala Leu 
            100                 105                 110         


Arg Ser Thr Arg Arg Phe Val Met Leu Arg Asp Asn Ser Gly Asp Pro 
        115                 120                 125             


Ala Asp Pro His Lys Val Tyr Ala Leu Ser Arg Glu Leu Cys Trp Arg 
    130                 135                 140                 


Glu Gly Pro Gly Thr Asp Gln Thr Glu Ala Glu Ala Pro Ala Ala Val 
145                 150                 155                 160 


Pro Pro Pro Gln Gly Gly Pro Pro Gly Pro Phe Leu Ala His Thr His 
                165                 170                 175     


Ala Gly Leu Gln Ala Pro Gly Pro Leu Pro Ala Pro Ala Gly Asp Lys 
            180                 185                 190         


Gly Asp Leu Leu Leu Gln Ala Val Gln Gln Ser Cys Leu Ala Asp His 
        195                 200                 205             


Leu Leu Thr Ala Ser Trp Gly Ala Asp Pro Val Pro Thr Lys Ala Pro 
    210                 215                 220                 


Gly Glu Gly Gln Glu Gly Leu Pro Leu Thr Gly Ala Cys Ala Gly Gly 
225                 230                 235                 240 


Pro Gly Leu Pro Ala Gly Glu Leu Tyr Gly Trp Ala Val Glu Thr Thr 
                245                 250                 255     


Pro Ser Pro Gly Pro Gln Pro Ala Ala Leu Thr Thr Gly Glu Ala Ala 
            260                 265                 270         


Ala Pro Glu Ser Pro His Gln Ala Glu Pro Tyr Leu Ser Pro Ser Pro 
        275                 280                 285             


Ser Ala Cys Thr Ala Val Gln Glu Pro Ser Pro Gly Ala Leu Asp Val 
    290                 295                 300                 


Thr Ile Met Tyr Lys Gly Arg Thr Val Leu Gln Lys Val Val Gly His 
305                 310                 315                 320 


Pro Ser Cys Thr Phe Leu Tyr Gly Pro Pro Asp Pro Ala Val Arg Ala 
                325                 330                 335     


Thr Asp Pro Gln Gln Val Ala Phe Pro Ser Pro Ala Glu Leu Pro Asp 
            340                 345                 350         


Gln Lys Gln Leu Arg Tyr Thr Glu Glu Leu Leu Arg His Val Ala Pro 
        355                 360                 365             


Gly Leu His Leu Glu Leu Arg Gly Pro Gln Leu Trp Ala Arg Arg Met 
    370                 375                 380                 


Gly Lys Cys Lys Val Tyr Trp Glu Val Gly Gly Pro Pro Gly Ser Ala 
385                 390                 395                 400 


Ser Pro Ser Thr Pro Ala Cys Leu Leu Pro Arg Asn Cys Asp Thr Pro 
                405                 410                 415     


Ile Phe Asp Phe Arg Val Phe Phe Gln Glu Leu Val Glu Phe Arg Ala 
            420                 425                 430         


Arg Gln Arg Arg Gly Ser Pro Arg Tyr Thr Ile Tyr Leu Gly Phe Gly 
        435                 440                 445             


Gln Asp Leu Ser Ala Gly Arg Pro Lys Glu Lys Ser Leu Val Leu Val 
    450                 455                 460                 


Lys Leu Glu Pro Trp Leu Cys Arg Val His Leu Glu Gly Thr Gln Arg 
465                 470                 475                 480 


Glu Gly Val Ser Ser Leu Asp Ser Ser Ser Leu Ser Leu Cys Leu Ser 
                485                 490                 495     


Ser Ala Asn Ser Leu Tyr Asp Asp Ile Glu Cys Phe Leu Met Glu Leu 
            500                 505                 510         


Glu Gln Pro Ala 
        515     


<210>  2778
<211>  310
<212>  PRT
<213>  homo sapiens

<400>  2778

Met Val Tyr Lys Thr Leu Phe Ala Leu Cys Ile Leu Thr Ala Gly Trp 
1               5                   10                  15      


Arg Val Gln Ser Leu Pro Thr Ser Ala Pro Leu Ser Val Ser Leu Pro 
            20                  25                  30          


Thr Asn Ile Val Pro Pro Thr Thr Ile Trp Thr Ser Ser Pro Gln Asn 
        35                  40                  45              


Thr Asp Ala Asp Thr Ala Ser Pro Ser Asn Gly Thr His Asn Asn Ser 
    50                  55                  60                  


Val Leu Pro Val Thr Ala Ser Ala Pro Thr Ser Leu Leu Pro Lys Asn 
65                  70                  75                  80  


Ile Ser Ile Glu Ser Arg Glu Glu Glu Ile Thr Ser Pro Gly Ser Asn 
                85                  90                  95      


Trp Glu Gly Thr Asn Thr Asp Pro Ser Pro Ser Gly Phe Ser Ser Thr 
            100                 105                 110         


Ser Gly Gly Val His Leu Thr Thr Thr Leu Glu Glu His Ser Ser Gly 
        115                 120                 125             


Thr Pro Glu Ala Gly Val Ala Ala Thr Leu Ser Gln Ser Ala Ala Glu 
    130                 135                 140                 


Pro Pro Thr Leu Ile Ser Pro Gln Ala Pro Ala Ser Ser Pro Ser Ser 
145                 150                 155                 160 


Leu Ser Thr Ser Pro Pro Glu Val Phe Ser Ala Ser Val Thr Thr Asn 
                165                 170                 175     


His Ser Ser Thr Val Thr Ser Thr Gln Pro Thr Gly Ala Pro Thr Ala 
            180                 185                 190         


Pro Glu Ser Pro Thr Glu Glu Ser Ser Ser Asp His Thr Pro Thr Ser 
        195                 200                 205             


His Ala Thr Ala Glu Pro Val Pro Gln Glu Lys Thr Pro Pro Thr Thr 
    210                 215                 220                 


Val Ser Gly Lys Val Met Cys Glu Leu Ile Asp Met Glu Thr Thr Thr 
225                 230                 235                 240 


Thr Phe Pro Arg Val Ile Met Gln Glu Val Glu His Ala Leu Ser Ser 
                245                 250                 255     


Gly Ser Ile Ala Ala Ile Thr Val Thr Val Ile Ala Val Val Leu Leu 
            260                 265                 270         


Val Phe Gly Val Ala Ala Tyr Leu Lys Ile Arg His Ser Ser Tyr Gly 
        275                 280                 285             


Arg Leu Leu Asp Asp His Asp Tyr Gly Ser Trp Gly Asn Tyr Asn Asn 
    290                 295                 300                 


Pro Leu Tyr Asp Asp Ser 
305                 310 


<210>  2779
<211>  654
<212>  PRT
<213>  homo sapiens

<400>  2779

Met Asn Gln Pro Gln Arg Met Ala Pro Val Gly Thr Asp Lys Glu Leu 
1               5                   10                  15      


Ser Asp Leu Leu Asp Phe Ser Met Met Phe Pro Leu Pro Val Thr Asn 
            20                  25                  30          


Gly Lys Gly Arg Pro Ala Ser Leu Ala Gly Ala Gln Phe Gly Gly Ser 
        35                  40                  45              


Gly Leu Glu Asp Arg Pro Ser Ser Gly Ser Trp Gly Ser Gly Asp Gln 
    50                  55                  60                  


Ser Ser Ser Ser Phe Asp Pro Ser Arg Thr Phe Ser Glu Gly Thr His 
65                  70                  75                  80  


Phe Thr Glu Ser His Ser Ser Leu Ser Ser Ser Thr Phe Leu Gly Pro 
                85                  90                  95      


Gly Leu Gly Gly Lys Ser Gly Glu Arg Gly Ala Tyr Ala Ser Phe Gly 
            100                 105                 110         


Arg Asp Ala Gly Val Gly Gly Leu Thr Gln Ala Gly Phe Leu Ser Gly 
        115                 120                 125             


Glu Leu Ala Leu Asn Ser Pro Gly Pro Leu Ser Pro Ser Gly Met Lys 
    130                 135                 140                 


Gly Thr Ser Gln Tyr Tyr Pro Ser Tyr Ser Gly Ser Ser Arg Arg Arg 
145                 150                 155                 160 


Ala Ala Asp Gly Ser Leu Asp Thr Gln Pro Lys Lys Val Arg Lys Val 
                165                 170                 175     


Pro Pro Gly Leu Pro Ser Ser Val Tyr Pro Pro Ser Ser Gly Glu Asp 
            180                 185                 190         


Tyr Gly Arg Asp Ala Thr Ala Tyr Pro Ser Ala Lys Thr Pro Ser Ser 
        195                 200                 205             


Thr Tyr Pro Ala Pro Phe Tyr Val Ala Asp Gly Ser Leu His Pro Ser 
    210                 215                 220                 


Ala Glu Leu Trp Ser Pro Pro Gly Gln Ala Gly Phe Gly Pro Met Leu 
225                 230                 235                 240 


Gly Gly Gly Ser Ser Pro Leu Pro Leu Pro Pro Gly Ser Gly Pro Val 
                245                 250                 255     


Gly Ser Ser Gly Ser Ser Ser Thr Phe Gly Gly Leu His Gln His Glu 
            260                 265                 270         


Arg Met Gly Tyr Gln Leu His Gly Ala Glu Val Asn Gly Gly Leu Pro 
        275                 280                 285             


Ser Ala Ser Ser Phe Ser Ser Ala Pro Gly Ala Thr Tyr Gly Gly Val 
    290                 295                 300                 


Ser Ser His Thr Pro Pro Val Ser Gly Ala Asp Ser Leu Leu Gly Ser 
305                 310                 315                 320 


Arg Gly Thr Thr Ala Gly Ser Ser Gly Asp Ala Leu Gly Lys Ala Leu 
                325                 330                 335     


Ala Ser Ile Tyr Ser Pro Asp His Ser Ser Asn Asn Phe Ser Ser Ser 
            340                 345                 350         


Pro Ser Thr Pro Val Gly Ser Pro Gln Gly Leu Ala Gly Thr Ser Gln 
        355                 360                 365             


Trp Pro Arg Ala Gly Ala Pro Gly Ala Leu Ser Pro Ser Tyr Asp Gly 
    370                 375                 380                 


Gly Leu His Gly Leu Gln Ser Lys Ile Glu Asp His Leu Asp Glu Ala 
385                 390                 395                 400 


Ile His Val Leu Arg Ser His Ala Val Gly Thr Ala Gly Asp Met His 
                405                 410                 415     


Thr Leu Leu Pro Gly His Gly Ala Leu Ala Ser Gly Phe Thr Gly Pro 
            420                 425                 430         


Met Ser Leu Gly Gly Arg His Ala Gly Leu Val Gly Gly Ser His Pro 
        435                 440                 445             


Glu Asp Gly Leu Ala Gly Ser Thr Ser Leu Met His Asn His Ala Ala 
    450                 455                 460                 


Leu Pro Ser Gln Pro Gly Thr Leu Pro Asp Leu Ser Arg Pro Pro Asp 
465                 470                 475                 480 


Ser Tyr Ser Gly Leu Gly Arg Ala Gly Ala Thr Ala Ala Ala Ser Glu 
                485                 490                 495     


Ile Lys Arg Glu Glu Lys Glu Asp Glu Glu Asn Thr Ser Ala Ala Asp 
            500                 505                 510         


His Ser Glu Glu Glu Lys Lys Glu Leu Lys Ala Pro Arg Ala Arg Thr 
        515                 520                 525             


Ser Pro Asp Glu Asp Glu Asp Asp Leu Leu Pro Pro Glu Gln Lys Ala 
    530                 535                 540                 


Glu Arg Glu Lys Glu Arg Arg Val Ala Asn Asn Ala Arg Glu Arg Leu 
545                 550                 555                 560 


Arg Val Arg Asp Ile Asn Glu Ala Phe Lys Glu Leu Gly Arg Met Cys 
                565                 570                 575     


Gln Leu His Leu Asn Ser Glu Lys Pro Gln Thr Lys Leu Leu Ile Leu 
            580                 585                 590         


His Gln Ala Val Ser Val Ile Leu Asn Leu Glu Gln Gln Val Arg Glu 
        595                 600                 605             


Arg Asn Leu Asn Pro Lys Ala Ala Cys Leu Lys Arg Arg Glu Glu Glu 
    610                 615                 620                 


Lys Val Ser Gly Val Val Gly Asp Pro Gln Met Val Leu Ser Ala Pro 
625                 630                 635                 640 


His Pro Gly Leu Ser Glu Ala His Asn Pro Ala Gly His Met 
                645                 650                 


<210>  2780
<211>  250
<212>  PRT
<213>  homo sapiens

<400>  2780

Met Thr Pro Gly Arg Cys Cys Leu Ala Ala Asp Ile Gln Val Glu Thr 
1               5                   10                  15      


Phe Ile Phe Thr Asp Gly Glu Asp Glu Ala Leu Ala Arg His Thr Gly 
            20                  25                  30          


Asn Val Val Ile Thr Asn Cys Ser Ala Ala His Ser Arg Gln Ala Leu 
        35                  40                  45              


Ser Cys Lys Met Ala Val Glu Tyr Asp Arg Phe Ile Glu Ser Gly Arg 
    50                  55                  60                  


Lys Trp Phe Cys His Val Asp Asp Asp Asn Tyr Val Asn Leu Arg Ala 
65                  70                  75                  80  


Leu Leu Arg Leu Leu Ala Ser Tyr Pro His Thr Arg Asp Val Tyr Val 
                85                  90                  95      


Gly Lys Pro Ser Leu Asp Arg Pro Ile Gln Ala Met Glu Arg Val Ser 
            100                 105                 110         


Glu Asn Lys Val Arg Pro Val His Phe Trp Phe Ala Thr Gly Gly Ala 
        115                 120                 125             


Gly Phe Cys Ile Ser Arg Gly Leu Ala Leu Lys Met Ser Pro Trp Ala 
    130                 135                 140                 


Ser Gly Gly His Phe Met Asn Thr Ala Glu Arg Ile Arg Leu Pro Asp 
145                 150                 155                 160 


Asp Cys Thr Ile Gly Tyr Ile Val Glu Ala Leu Leu Gly Val Pro Leu 
                165                 170                 175     


Ile Arg Ser Gly Leu Phe His Ser His Leu Glu Asn Leu Gln Gln Val 
            180                 185                 190         


Pro Thr Ser Glu Leu His Glu Gln Val Thr Leu Ser Tyr Gly Met Phe 
        195                 200                 205             


Glu Asn Lys Arg Asn Ala Val His Val Lys Gly Pro Phe Ser Val Glu 
    210                 215                 220                 


Ala Asp Pro Ser Arg Phe Arg Ser Ile His Cys His Leu Tyr Pro Asp 
225                 230                 235                 240 


Thr Pro Trp Cys Pro Arg Thr Ala Ile Phe 
                245                 250 


<210>  2781
<211>  379
<212>  PRT
<213>  homo sapiens

<400>  2781

Met Leu Lys Arg Cys Gly Arg Arg Leu Leu Leu Ala Leu Ala Gly Ala 
1               5                   10                  15      


Leu Leu Ala Cys Leu Leu Val Leu Thr Ala Asp Pro Pro Pro Pro Pro 
            20                  25                  30          


Leu Pro Ala Glu Arg Gly Arg Arg Ala Leu Arg Ser Leu Ala Gly Pro 
        35                  40                  45              


Ala Gly Ala Ala Pro Ala Pro Gly Leu Gly Ala Ala Ala Ala Ala Pro 
    50                  55                  60                  


Gly Ala Leu Val Arg Asp Val His Ser Leu Ser Glu Tyr Phe Ser Leu 
65                  70                  75                  80  


Leu Thr Arg Ala Arg Arg Asp Ala Gly Pro Pro Pro Gly Ala Ala Pro 
                85                  90                  95      


Arg Pro Ala Asp Gly His Pro Arg Pro Leu Ala Glu Pro Leu Ala Pro 
            100                 105                 110         


Arg Asp Val Phe Ile Ala Val Lys Thr Thr Lys Lys Phe His Arg Ala 
        115                 120                 125             


Arg Leu Asp Leu Leu Leu Glu Thr Trp Ile Ser Arg His Lys Glu Met 
    130                 135                 140                 


Thr Phe Ile Phe Thr Asp Gly Glu Asp Glu Ala Leu Ala Arg His Thr 
145                 150                 155                 160 


Gly Asn Val Val Ile Thr Asn Cys Ser Ala Ala His Ser Arg Gln Ala 
                165                 170                 175     


Leu Ser Cys Lys Met Ala Val Glu Tyr Asp Arg Phe Ile Glu Ser Gly 
            180                 185                 190         


Arg Lys Trp Phe Cys His Val Asp Asp Asp Asn Tyr Val Asn Leu Arg 
        195                 200                 205             


Ala Leu Leu Arg Leu Leu Ala Ser Tyr Pro His Thr Arg Asp Val Tyr 
    210                 215                 220                 


Val Gly Lys Pro Ser Leu Asp Arg Pro Ile Gln Ala Met Glu Arg Val 
225                 230                 235                 240 


Ser Glu Asn Lys Val Arg Pro Val His Phe Trp Phe Ala Thr Gly Gly 
                245                 250                 255     


Ala Gly Phe Cys Ile Ser Arg Gly Leu Ala Leu Lys Met Ser Pro Trp 
            260                 265                 270         


Ala Ser Gly Gly His Phe Met Asn Thr Ala Glu Arg Ile Arg Leu Pro 
        275                 280                 285             


Asp Asp Cys Thr Ile Gly Tyr Ile Val Glu Ala Leu Leu Gly Val Pro 
    290                 295                 300                 


Leu Ile Arg Ser Gly Leu Phe His Ser His Leu Glu Asn Leu Gln Gln 
305                 310                 315                 320 


Val Pro Thr Ser Glu Leu His Glu Gln Val Thr Leu Ser Tyr Gly Met 
                325                 330                 335     


Phe Glu Asn Lys Arg Asn Ala Val His Val Lys Gly Pro Phe Ser Val 
            340                 345                 350         


Glu Ala Asp Pro Ser Arg Phe Arg Ser Ile His Cys His Leu Tyr Pro 
        355                 360                 365             


Asp Thr Pro Trp Cys Pro Arg Thr Ala Ile Phe 
    370                 375                 


<210>  2782
<211>  1183
<212>  PRT
<213>  homo sapiens

<400>  2782

Met Gln Leu Lys Ile Met Pro Lys Lys Lys Arg Leu Ser Ala Gly Arg 
1               5                   10                  15      


Val Pro Leu Ile Leu Phe Leu Cys Gln Met Ile Ser Ala Leu Glu Val 
            20                  25                  30          


Pro Leu Asp Leu Val Gln Pro Pro Thr Ile Thr Gln Gln Ser Pro Lys 
        35                  40                  45              


Asp Tyr Ile Ile Asp Pro Arg Glu Asn Ile Val Ile Gln Cys Glu Ala 
    50                  55                  60                  


Lys Gly Lys Pro Pro Pro Ser Phe Ser Trp Thr Arg Asn Gly Thr His 
65                  70                  75                  80  


Phe Asp Ile Asp Lys Asp Pro Leu Val Thr Met Lys Pro Gly Thr Gly 
                85                  90                  95      


Thr Leu Ile Ile Asn Ile Met Ser Glu Gly Lys Ala Glu Thr Tyr Glu 
            100                 105                 110         


Gly Val Tyr Gln Cys Thr Ala Arg Asn Glu Arg Gly Ala Ala Val Ser 
        115                 120                 125             


Asn Asn Ile Val Val Arg Pro Ser Arg Ser Pro Leu Trp Thr Lys Glu 
    130                 135                 140                 


Lys Leu Glu Pro Ile Thr Leu Gln Ser Gly Gln Ser Leu Val Leu Pro 
145                 150                 155                 160 


Cys Arg Pro Pro Ile Gly Leu Pro Pro Pro Ile Ile Phe Trp Met Asp 
                165                 170                 175     


Asn Ser Phe Gln Arg Leu Pro Gln Ser Glu Arg Val Ser Gln Gly Leu 
            180                 185                 190         


Asn Gly Asp Leu Tyr Phe Ser Asn Val Leu Pro Glu Asp Thr Arg Glu 
        195                 200                 205             


Asp Tyr Ile Cys Tyr Ala Arg Phe Asn His Thr Gln Thr Ile Gln Gln 
    210                 215                 220                 


Lys Gln Pro Ile Ser Val Lys Val Ile Ser Val Asp Glu Leu Asn Asp 
225                 230                 235                 240 


Thr Ile Ala Ala Asn Leu Ser Asp Thr Glu Phe Tyr Gly Ala Lys Ser 
                245                 250                 255     


Ser Arg Glu Arg Pro Pro Thr Phe Leu Thr Pro Glu Gly Asn Ala Ser 
            260                 265                 270         


Asn Lys Glu Glu Leu Arg Gly Asn Val Leu Ser Leu Glu Cys Ile Ala 
        275                 280                 285             


Glu Gly Leu Pro Thr Pro Ile Ile Tyr Trp Ala Lys Glu Asp Gly Met 
    290                 295                 300                 


Leu Pro Lys Asn Arg Thr Val Tyr Lys Asn Phe Glu Lys Thr Leu Gln 
305                 310                 315                 320 


Ile Ile His Val Ser Glu Ala Asp Ser Gly Asn Tyr Gln Cys Ile Ala 
                325                 330                 335     


Lys Asn Ala Leu Gly Ala Ile His His Thr Ile Ser Val Arg Val Lys 
            340                 345                 350         


Ala Ala Pro Tyr Trp Ile Thr Ala Pro Gln Asn Leu Val Leu Ser Pro 
        355                 360                 365             


Gly Glu Asp Gly Thr Leu Ile Cys Arg Ala Asn Gly Asn Pro Lys Pro 
    370                 375                 380                 


Arg Ile Ser Trp Leu Thr Asn Gly Val Pro Ile Glu Ile Ala Pro Asp 
385                 390                 395                 400 


Asp Pro Ser Arg Lys Ile Asp Gly Asp Thr Ile Ile Phe Ser Asn Val 
                405                 410                 415     


Gln Glu Arg Ser Ser Ala Val Tyr Gln Cys Asn Ala Ser Asn Glu Tyr 
            420                 425                 430         


Gly Tyr Leu Leu Ala Asn Ala Phe Val Asn Val Leu Ala Glu Pro Pro 
        435                 440                 445             


Arg Ile Leu Thr Pro Ala Asn Thr Leu Tyr Gln Val Ile Ala Asn Arg 
    450                 455                 460                 


Pro Ala Leu Leu Asp Cys Ala Phe Phe Gly Ser Pro Leu Pro Thr Ile 
465                 470                 475                 480 


Glu Trp Phe Lys Gly Ala Lys Gly Ser Ala Leu His Glu Asp Ile Tyr 
                485                 490                 495     


Val Leu His Glu Asn Gly Thr Leu Glu Ile Pro Val Ala Gln Lys Asp 
            500                 505                 510         


Ser Thr Gly Thr Tyr Thr Cys Val Ala Arg Asn Lys Leu Gly Met Ala 
        515                 520                 525             


Lys Asn Glu Val His Leu Glu Ile Lys Asp Pro Thr Trp Ile Val Lys 
    530                 535                 540                 


Gln Pro Glu Tyr Ala Val Val Gln Arg Gly Ser Met Val Ser Phe Glu 
545                 550                 555                 560 


Cys Lys Val Lys His Asp His Thr Leu Ser Leu Thr Val Leu Trp Leu 
                565                 570                 575     


Lys Asp Asn Arg Glu Leu Pro Ser Asp Glu Arg Phe Thr Val Asp Lys 
            580                 585                 590         


Asp His Leu Val Val Ala Asp Val Ser Asp Asp Asp Ser Gly Thr Tyr 
        595                 600                 605             


Thr Cys Val Ala Asn Thr Thr Leu Asp Ser Val Ser Ala Ser Ala Val 
    610                 615                 620                 


Leu Ser Val Val Asp Val Pro Asn Pro Pro Phe Asp Leu Glu Leu Thr 
625                 630                 635                 640 


Asp Gln Leu Asp Lys Ser Val Gln Leu Ser Trp Thr Pro Gly Asp Asp 
                645                 650                 655     


Asn Asn Ser Pro Ile Thr Lys Phe Ile Ile Glu Tyr Glu Asp Ala Met 
            660                 665                 670         


His Lys Pro Gly Leu Trp His His Gln Thr Glu Val Ser Gly Thr Gln 
        675                 680                 685             


Thr Thr Ala Gln Leu Lys Leu Ser Pro Tyr Val Asn Tyr Ser Phe Arg 
    690                 695                 700                 


Val Met Ala Val Asn Ser Ile Gly Lys Ser Leu Pro Ser Glu Ala Ser 
705                 710                 715                 720 


Glu Gln Tyr Leu Thr Lys Ala Ser Glu Pro Asp Lys Asn Pro Thr Ala 
                725                 730                 735     


Val Glu Gly Leu Gly Ser Glu Pro Asp Asn Leu Val Ile Thr Trp Lys 
            740                 745                 750         


Pro Leu Asn Gly Phe Glu Ser Asn Gly Pro Gly Leu Gln Tyr Lys Val 
        755                 760                 765             


Ser Trp Arg Gln Lys Asp Gly Asp Asp Glu Trp Thr Ser Val Val Val 
    770                 775                 780                 


Ala Asn Val Ser Lys Tyr Ile Val Ser Gly Thr Pro Thr Phe Val Pro 
785                 790                 795                 800 


Tyr Leu Ile Lys Val Gln Ala Leu Asn Asp Met Gly Phe Ala Pro Glu 
                805                 810                 815     


Pro Ala Val Val Met Gly His Ser Gly Glu Asp Leu Pro Met Val Ala 
            820                 825                 830         


Pro Gly Asn Val Arg Val Asn Val Val Asn Ser Thr Leu Ala Glu Val 
        835                 840                 845             


His Trp Asp Pro Val Pro Leu Lys Ser Ile Arg Gly His Leu Gln Gly 
    850                 855                 860                 


Tyr Arg Ile Tyr Tyr Trp Lys Thr Gln Ser Ser Ser Lys Arg Asn Arg 
865                 870                 875                 880 


Arg His Ile Glu Lys Lys Ile Leu Thr Phe Gln Gly Ser Lys Thr His 
                885                 890                 895     


Gly Met Leu Pro Gly Leu Glu Pro Phe Ser His Tyr Thr Leu Asn Val 
            900                 905                 910         


Arg Val Val Asn Gly Lys Gly Glu Gly Pro Ala Ser Pro Asp Arg Val 
        915                 920                 925             


Phe Asn Thr Pro Glu Gly Val Pro Ser Ala Pro Ser Ser Leu Lys Ile 
    930                 935                 940                 


Val Asn Pro Thr Leu Asp Ser Leu Thr Leu Glu Trp Asp Pro Pro Ser 
945                 950                 955                 960 


His Pro Asn Gly Ile Leu Thr Glu Tyr Thr Leu Lys Tyr Gln Pro Ile 
                965                 970                 975     


Asn Ser Thr His Glu Leu Gly Pro Leu Val Asp Leu Lys Ile Pro Ala 
            980                 985                 990         


Asn Lys Thr Arg Trp Thr Leu Lys  Asn Leu Asn Phe Ser  Thr Arg Tyr 
        995                 1000                 1005             


Lys Phe  Tyr Phe Tyr Ala Gln  Thr Ser Ala Gly Ser  Gly Ser Gln 
    1010                 1015                 1020             


Ile Thr  Glu Glu Ala Val Thr  Thr Val Asp Glu Ala  Met Ala Ser 
    1025                 1030                 1035             


Arg Gln  Val Asp Ile Ala Thr  Gln Gly Trp Phe Ile  Gly Leu Met 
    1040                 1045                 1050             


Cys Ala  Val Ala Leu Leu Ile  Leu Ile Leu Leu Ile  Val Cys Phe 
    1055                 1060                 1065             


Ile Arg  Arg Asn Lys Gly Gly  Lys Tyr Pro Val Lys  Glu Lys Glu 
    1070                 1075                 1080             


Asp Ala  His Ala Asp Pro Glu  Ile Gln Pro Met Lys  Glu Asp Asp 
    1085                 1090                 1095             


Gly Thr  Phe Gly Glu Tyr Ser  Asp Ala Glu Asp His  Lys Pro Leu 
    1100                 1105                 1110             


Lys Lys  Gly Ser Arg Thr Pro  Ser Asp Arg Thr Val  Lys Lys Glu 
    1115                 1120                 1125             


Asp Ser  Asp Asp Ser Leu Val  Asp Tyr Gly Glu Gly  Val Asn Gly 
    1130                 1135                 1140             


Gln Phe  Asn Glu Asp Gly Ser  Phe Ile Gly Gln Tyr  Ser Gly Lys 
    1145                 1150                 1155             


Lys Glu  Lys Glu Pro Ala Glu  Gly Asn Glu Ser Ser  Glu Ala Pro 
    1160                 1165                 1170             


Ser Pro  Val Asn Ala Met Asn  Ser Phe Val 
    1175                 1180             


<210>  2783
<211>  1304
<212>  PRT
<213>  homo sapiens

<400>  2783

Met Gln Leu Lys Ile Met Pro Lys Lys Lys Arg Leu Ser Ala Gly Arg 
1               5                   10                  15      


Val Pro Leu Ile Leu Phe Leu Cys Gln Met Ile Ser Ala Leu Glu Val 
            20                  25                  30          


Pro Leu Asp Pro Lys Leu Leu Glu Asp Leu Val Gln Pro Pro Thr Ile 
        35                  40                  45              


Thr Gln Gln Ser Pro Lys Asp Tyr Ile Ile Asp Pro Arg Glu Asn Ile 
    50                  55                  60                  


Val Ile Gln Cys Glu Ala Lys Gly Lys Pro Pro Pro Ser Phe Ser Trp 
65                  70                  75                  80  


Thr Arg Asn Gly Thr His Phe Asp Ile Asp Lys Asp Pro Leu Val Thr 
                85                  90                  95      


Met Lys Pro Gly Thr Gly Thr Leu Ile Ile Asn Ile Met Ser Glu Gly 
            100                 105                 110         


Lys Ala Glu Thr Tyr Glu Gly Val Tyr Gln Cys Thr Ala Arg Asn Glu 
        115                 120                 125             


Arg Gly Ala Ala Val Ser Asn Asn Ile Val Val Arg Pro Ser Arg Ser 
    130                 135                 140                 


Pro Leu Trp Thr Lys Glu Lys Leu Glu Pro Ile Thr Leu Gln Ser Gly 
145                 150                 155                 160 


Gln Ser Leu Val Leu Pro Cys Arg Pro Pro Ile Gly Leu Pro Pro Pro 
                165                 170                 175     


Ile Ile Phe Trp Met Asp Asn Ser Phe Gln Arg Leu Pro Gln Ser Glu 
            180                 185                 190         


Arg Val Ser Gln Gly Leu Asn Gly Asp Leu Tyr Phe Ser Asn Val Leu 
        195                 200                 205             


Pro Glu Asp Thr Arg Glu Asp Tyr Ile Cys Tyr Ala Arg Phe Asn His 
    210                 215                 220                 


Thr Gln Thr Ile Gln Gln Lys Gln Pro Ile Ser Val Lys Val Ile Ser 
225                 230                 235                 240 


Val Asp Glu Leu Asn Asp Thr Ile Ala Ala Asn Leu Ser Asp Thr Glu 
                245                 250                 255     


Phe Tyr Gly Ala Lys Ser Ser Arg Glu Arg Pro Pro Thr Phe Leu Thr 
            260                 265                 270         


Pro Glu Gly Asn Ala Ser Asn Lys Glu Glu Leu Arg Gly Asn Val Leu 
        275                 280                 285             


Ser Leu Glu Cys Ile Ala Glu Gly Leu Pro Thr Pro Ile Ile Tyr Trp 
    290                 295                 300                 


Ala Lys Glu Asp Gly Met Leu Pro Lys Asn Arg Thr Val Tyr Lys Asn 
305                 310                 315                 320 


Phe Glu Lys Thr Leu Gln Ile Ile His Val Ser Glu Ala Asp Ser Gly 
                325                 330                 335     


Asn Tyr Gln Cys Ile Ala Lys Asn Ala Leu Gly Ala Ile His His Thr 
            340                 345                 350         


Ile Ser Val Arg Val Lys Ala Ala Pro Tyr Trp Ile Thr Ala Pro Gln 
        355                 360                 365             


Asn Leu Val Leu Ser Pro Gly Glu Asp Gly Thr Leu Ile Cys Arg Ala 
    370                 375                 380                 


Asn Gly Asn Pro Lys Pro Arg Ile Ser Trp Leu Thr Asn Gly Val Pro 
385                 390                 395                 400 


Ile Glu Ile Ala Pro Asp Asp Pro Ser Arg Lys Ile Asp Gly Asp Thr 
                405                 410                 415     


Ile Ile Phe Ser Asn Val Gln Glu Arg Ser Ser Ala Val Tyr Gln Cys 
            420                 425                 430         


Asn Ala Ser Asn Glu Tyr Gly Tyr Leu Leu Ala Asn Ala Phe Val Asn 
        435                 440                 445             


Val Leu Ala Glu Pro Pro Arg Ile Leu Thr Pro Ala Asn Thr Leu Tyr 
    450                 455                 460                 


Gln Val Ile Ala Asn Arg Pro Ala Leu Leu Asp Cys Ala Phe Phe Gly 
465                 470                 475                 480 


Ser Pro Leu Pro Thr Ile Glu Trp Phe Lys Gly Ala Lys Gly Ser Ala 
                485                 490                 495     


Leu His Glu Asp Ile Tyr Val Leu His Glu Asn Gly Thr Leu Glu Ile 
            500                 505                 510         


Pro Val Ala Gln Lys Asp Ser Thr Gly Thr Tyr Thr Cys Val Ala Arg 
        515                 520                 525             


Asn Lys Leu Gly Met Ala Lys Asn Glu Val His Leu Glu Ile Lys Asp 
    530                 535                 540                 


Pro Thr Trp Ile Val Lys Gln Pro Glu Tyr Ala Val Val Gln Arg Gly 
545                 550                 555                 560 


Ser Met Val Ser Phe Glu Cys Lys Val Lys His Asp His Thr Leu Ser 
                565                 570                 575     


Leu Thr Val Leu Trp Leu Lys Asp Asn Arg Glu Leu Pro Ser Asp Glu 
            580                 585                 590         


Arg Phe Thr Val Asp Lys Asp His Leu Val Val Ala Asp Val Ser Asp 
        595                 600                 605             


Asp Asp Ser Gly Thr Tyr Thr Cys Val Ala Asn Thr Thr Leu Asp Ser 
    610                 615                 620                 


Val Ser Ala Ser Ala Val Leu Ser Val Val Ala Pro Thr Pro Thr Pro 
625                 630                 635                 640 


Ala Pro Val Tyr Asp Val Pro Asn Pro Pro Phe Asp Leu Glu Leu Thr 
                645                 650                 655     


Asp Gln Leu Asp Lys Ser Val Gln Leu Ser Trp Thr Pro Gly Asp Asp 
            660                 665                 670         


Asn Asn Ser Pro Ile Thr Lys Phe Ile Ile Glu Tyr Glu Asp Ala Met 
        675                 680                 685             


His Lys Pro Gly Leu Trp His His Gln Thr Glu Val Ser Gly Thr Gln 
    690                 695                 700                 


Thr Thr Ala Gln Leu Lys Leu Ser Pro Tyr Val Asn Tyr Ser Phe Arg 
705                 710                 715                 720 


Val Met Ala Val Asn Ser Ile Gly Lys Ser Leu Pro Ser Glu Ala Ser 
                725                 730                 735     


Glu Gln Tyr Leu Thr Lys Ala Ser Glu Pro Asp Lys Asn Pro Thr Ala 
            740                 745                 750         


Val Glu Gly Leu Gly Ser Glu Pro Asp Asn Leu Val Ile Thr Trp Lys 
        755                 760                 765             


Pro Leu Asn Gly Phe Glu Ser Asn Gly Pro Gly Leu Gln Tyr Lys Val 
    770                 775                 780                 


Ser Trp Arg Gln Lys Asp Gly Asp Asp Glu Trp Thr Ser Val Val Val 
785                 790                 795                 800 


Ala Asn Val Ser Lys Tyr Ile Val Ser Gly Thr Pro Thr Phe Val Pro 
                805                 810                 815     


Tyr Leu Ile Lys Val Gln Ala Leu Asn Asp Met Gly Phe Ala Pro Glu 
            820                 825                 830         


Pro Ala Val Val Met Gly His Ser Gly Glu Asp Leu Pro Met Val Ala 
        835                 840                 845             


Pro Gly Asn Val Arg Val Asn Val Val Asn Ser Thr Leu Ala Glu Val 
    850                 855                 860                 


His Trp Asp Pro Val Pro Leu Lys Ser Ile Arg Gly His Leu Gln Gly 
865                 870                 875                 880 


Tyr Arg Ile Tyr Tyr Trp Lys Thr Gln Ser Ser Ser Lys Arg Asn Arg 
                885                 890                 895     


Arg His Ile Glu Lys Lys Ile Leu Thr Phe Gln Gly Ser Lys Thr His 
            900                 905                 910         


Gly Met Leu Pro Gly Leu Glu Pro Phe Ser His Tyr Thr Leu Asn Val 
        915                 920                 925             


Arg Val Val Asn Gly Lys Gly Glu Gly Pro Ala Ser Pro Asp Arg Val 
    930                 935                 940                 


Phe Asn Thr Pro Glu Gly Val Pro Ser Ala Pro Ser Ser Leu Lys Ile 
945                 950                 955                 960 


Val Asn Pro Thr Leu Asp Ser Leu Thr Leu Glu Trp Asp Pro Pro Ser 
                965                 970                 975     


His Pro Asn Gly Ile Leu Thr Glu Tyr Thr Leu Lys Tyr Gln Pro Ile 
            980                 985                 990         


Asn Ser Thr His Glu Leu Gly Pro  Leu Val Asp Leu Lys  Ile Pro Ala 
        995                 1000                 1005             


Asn Lys  Thr Arg Trp Thr Leu  Lys Asn Leu Asn Phe  Ser Thr Arg 
    1010                 1015                 1020             


Tyr Lys  Phe Tyr Phe Tyr Ala  Gln Thr Ser Ala Gly  Ser Gly Ser 
    1025                 1030                 1035             


Gln Ile  Thr Glu Glu Ala Val  Thr Thr Val Asp Glu  Ala Gly Ile 
    1040                 1045                 1050             


Leu Pro  Pro Asp Val Gly Ala  Gly Lys Val Gln Ala  Val Asn Pro 
    1055                 1060                 1065             


Arg Ile  Ser Asn Leu Thr Ala  Ala Ala Ala Glu Thr  Tyr Ala Asn 
    1070                 1075                 1080             


Ile Ser  Trp Glu Tyr Glu Gly  Pro Glu His Val Asn  Phe Tyr Val 
    1085                 1090                 1095             


Glu Tyr  Gly Val Ala Gly Ser  Lys Glu Glu Trp Arg  Lys Glu Ile 
    1100                 1105                 1110             


Val Asn  Gly Ser Arg Ser Phe  Phe Gly Leu Lys Gly  Leu Met Pro 
    1115                 1120                 1125             


Gly Thr  Ala Tyr Lys Val Arg  Val Gly Ala Val Gly  Asp Ser Gly 
    1130                 1135                 1140             


Phe Val  Ser Ser Glu Asp Val  Phe Glu Thr Gly Pro  Ala Met Ala 
    1145                 1150                 1155             


Ser Arg  Gln Val Asp Ile Ala  Thr Gln Gly Trp Phe  Ile Gly Leu 
    1160                 1165                 1170             


Met Cys  Ala Val Ala Leu Leu  Ile Leu Ile Leu Leu  Ile Val Cys 
    1175                 1180                 1185             


Phe Ile  Arg Arg Asn Lys Gly  Gly Lys Tyr Pro Val  Lys Glu Lys 
    1190                 1195                 1200             


Glu Asp  Ala His Ala Asp Pro  Glu Ile Gln Pro Met  Lys Glu Asp 
    1205                 1210                 1215             


Asp Gly  Thr Phe Gly Glu Tyr  Ser Asp Ala Glu Asp  His Lys Pro 
    1220                 1225                 1230             


Leu Lys  Lys Gly Ser Arg Thr  Pro Ser Asp Arg Thr  Val Lys Lys 
    1235                 1240                 1245             


Glu Asp  Ser Asp Asp Ser Leu  Val Asp Tyr Gly Glu  Gly Val Asn 
    1250                 1255                 1260             


Gly Gln  Phe Asn Glu Asp Gly  Ser Phe Ile Gly Gln  Tyr Ser Gly 
    1265                 1270                 1275             


Lys Lys  Glu Lys Glu Pro Ala  Glu Gly Asn Glu Ser  Ser Glu Ala 
    1280                 1285                 1290             


Pro Ser  Pro Val Asn Ala Met  Asn Ser Phe Val 
    1295                 1300                 


<210>  2784
<211>  333
<212>  PRT
<213>  homo sapiens

<400>  2784

Met Thr Glu Asn Ser Asp Lys Val Pro Ile Ala Leu Val Gly Pro Asp 
1               5                   10                  15      


Asp Val Glu Phe Cys Ser Pro Pro Ala Tyr Ala Thr Leu Thr Val Lys 
            20                  25                  30          


Pro Ser Ser Pro Ala Arg Leu Leu Lys Val Gly Ala Val Val Leu Ile 
        35                  40                  45              


Ser Gly Ala Val Leu Leu Leu Phe Gly Ala Ile Gly Ala Phe Tyr Phe 
    50                  55                  60                  


Trp Lys Gly Ser Asp Ser His Ile Tyr Asn Val His Tyr Thr Met Ser 
65                  70                  75                  80  


Ile Asn Gly Lys Leu Gln Asp Gly Ser Met Glu Ile Asp Ala Gly Asn 
                85                  90                  95      


Asn Leu Glu Thr Phe Lys Met Gly Ser Gly Ala Glu Glu Ala Ile Ala 
            100                 105                 110         


Val Asn Asp Phe Gln Asn Gly Ile Thr Gly Ile Arg Phe Ala Gly Gly 
        115                 120                 125             


Glu Lys Cys Tyr Ile Lys Ala Gln Val Lys Ala Arg Ile Pro Glu Val 
    130                 135                 140                 


Gly Ala Val Thr Lys Gln Ser Ile Ser Ser Lys Leu Glu Gly Lys Ile 
145                 150                 155                 160 


Met Pro Val Lys Tyr Glu Glu Asn Ser Leu Ile Trp Val Ala Val Asp 
                165                 170                 175     


Gln Pro Val Lys Asp Asn Ser Phe Leu Ser Ser Lys Val Leu Glu Leu 
            180                 185                 190         


Cys Gly Asp Leu Pro Ile Phe Trp Leu Lys Pro Thr Tyr Pro Lys Glu 
        195                 200                 205             


Ile Gln Arg Glu Arg Arg Glu Val Val Arg Lys Ile Val Pro Thr Thr 
    210                 215                 220                 


Thr Lys Arg Pro His Ser Gly Pro Arg Ser Asn Pro Gly Ala Gly Arg 
225                 230                 235                 240 


Leu Asn Asn Glu Thr Arg Pro Ser Val Gln Glu Asp Ser Gln Ala Phe 
                245                 250                 255     


Asn Pro Asp Asn Pro Tyr His Gln Glu Gly Glu Ser Met Thr Phe Asp 
            260                 265                 270         


Pro Arg Leu Asp His Glu Gly Ile Cys Cys Ile Glu Cys Arg Arg Ser 
        275                 280                 285             


Tyr Thr His Cys Gln Lys Ile Cys Glu Pro Leu Gly Gly Tyr Tyr Pro 
    290                 295                 300                 


Trp Pro Tyr Asn Tyr Gln Gly Cys Arg Ser Ala Cys Arg Val Ile Met 
305                 310                 315                 320 


Pro Cys Ser Trp Trp Val Ala Arg Ile Leu Gly Met Val 
                325                 330             


<210>  2785
<211>  399
<212>  PRT
<213>  homo sapiens

<400>  2785

Met Pro Gln Leu Ser Gly Gly Gly Gly Gly Gly Gly Gly Asp Pro Glu 
1               5                   10                  15      


Leu Cys Ala Thr Asp Glu Met Ile Pro Phe Lys Asp Glu Gly Asp Pro 
            20                  25                  30          


Gln Lys Glu Lys Ile Phe Ala Glu Ile Ser His Pro Glu Glu Glu Gly 
        35                  40                  45              


Asp Leu Ala Asp Ile Lys Ser Ser Leu Val Asn Glu Ser Glu Ile Ile 
    50                  55                  60                  


Pro Ala Ser Asn Gly His Glu Val Ala Arg Gln Ala Gln Thr Ser Gln 
65                  70                  75                  80  


Glu Pro Tyr His Asp Lys Ala Arg Glu His Pro Asp Asp Gly Lys His 
                85                  90                  95      


Pro Asp Gly Gly Leu Tyr Asn Lys Gly Pro Ser Tyr Ser Ser Tyr Ser 
            100                 105                 110         


Gly Tyr Ile Met Met Pro Asn Met Asn Asn Asp Pro Tyr Met Ser Asn 
        115                 120                 125             


Gly Ser Leu Ser Pro Pro Ile Pro Arg Thr Ser Asn Lys Val Pro Val 
    130                 135                 140                 


Val Gln Pro Ser His Ala Val His Pro Leu Thr Pro Leu Ile Thr Tyr 
145                 150                 155                 160 


Ser Asp Glu His Phe Ser Pro Gly Ser His Pro Ser His Ile Pro Ser 
                165                 170                 175     


Asp Val Asn Ser Lys Gln Gly Met Ser Arg His Pro Pro Ala Pro Asp 
            180                 185                 190         


Ile Pro Thr Phe Tyr Pro Leu Ser Pro Gly Gly Val Gly Gln Ile Thr 
        195                 200                 205             


Pro Pro Leu Gly Trp Gln Gly Gln Pro Val Tyr Pro Ile Thr Gly Gly 
    210                 215                 220                 


Phe Arg Gln Pro Tyr Pro Ser Ser Leu Ser Val Asp Thr Ser Met Ser 
225                 230                 235                 240 


Arg Phe Ser His His Met Ile Pro Gly Pro Pro Gly Pro His Thr Thr 
                245                 250                 255     


Gly Ile Pro His Pro Ala Ile Val Thr Pro Gln Val Lys Gln Glu His 
            260                 265                 270         


Pro His Thr Asp Ser Asp Leu Met His Val Lys Pro Gln His Glu Gln 
        275                 280                 285             


Arg Lys Glu Gln Glu Pro Lys Arg Pro His Ile Lys Lys Pro Leu Asn 
    290                 295                 300                 


Ala Phe Met Leu Tyr Met Lys Glu Met Arg Ala Asn Val Val Ala Glu 
305                 310                 315                 320 


Cys Thr Leu Lys Glu Ser Ala Ala Ile Asn Gln Ile Leu Gly Arg Arg 
                325                 330                 335     


Trp His Ala Leu Ser Arg Glu Glu Gln Ala Lys Tyr Tyr Glu Leu Ala 
            340                 345                 350         


Arg Lys Glu Arg Gln Leu His Met Gln Leu Tyr Pro Gly Trp Ser Ala 
        355                 360                 365             


Arg Asp Asn Tyr Gly Lys Lys Lys Lys Arg Lys Arg Glu Lys Leu Gln 
    370                 375                 380                 


Glu Ser Ala Ser Gly Thr Gly Pro Arg Met Thr Ala Ala Tyr Ile 
385                 390                 395                 


<210>  2786
<211>  773
<212>  PRT
<213>  homo sapiens

<400>  2786

Met Ser Arg Arg Lys Gln Gly Lys Pro Gln His Leu Ser Lys Arg Glu 
1               5                   10                  15      


Phe Ser Pro Glu Pro Leu Glu Ala Ile Leu Thr Asp Asp Glu Pro Asp 
            20                  25                  30          


His Gly Pro Leu Gly Ala Pro Glu Gly Asp His Asp Leu Leu Thr Cys 
        35                  40                  45              


Gly Gln Cys Gln Met Asn Phe Pro Leu Gly Asp Ile Leu Ile Phe Ile 
    50                  55                  60                  


Glu His Lys Arg Lys Gln Cys Asn Gly Ser Leu Cys Leu Glu Lys Ala 
65                  70                  75                  80  


Val Asp Lys Pro Pro Ser Pro Ser Pro Ile Glu Met Lys Lys Ala Ser 
                85                  90                  95      


Asn Pro Val Glu Val Gly Ile Gln Val Thr Pro Glu Asp Asp Asp Cys 
            100                 105                 110         


Leu Ser Thr Ser Ser Arg Gly Ile Cys Pro Lys Gln Glu His Ile Ala 
        115                 120                 125             


Asp Lys Leu Leu His Trp Arg Gly Leu Ser Ser Pro Arg Ser Ala His 
    130                 135                 140                 


Gly Ala Leu Ile Pro Thr Pro Gly Met Ser Ala Glu Tyr Ala Pro Gln 
145                 150                 155                 160 


Gly Ile Cys Lys Asp Glu Pro Ser Ser Tyr Thr Cys Thr Thr Cys Lys 
                165                 170                 175     


Gln Pro Phe Thr Ser Ala Trp Phe Leu Leu Gln His Ala Gln Asn Thr 
            180                 185                 190         


His Gly Leu Arg Ile Tyr Leu Glu Ser Glu His Gly Ser Pro Leu Thr 
        195                 200                 205             


Pro Arg Val Gly Ile Pro Ser Gly Leu Gly Ala Glu Cys Pro Ser Gln 
    210                 215                 220                 


Pro Pro Leu His Gly Ile His Ile Ala Asp Asn Asn Pro Phe Asn Leu 
225                 230                 235                 240 


Leu Arg Ile Pro Gly Ser Val Ser Arg Glu Ala Ser Gly Leu Ala Glu 
                245                 250                 255     


Gly Arg Phe Pro Pro Thr Pro Pro Leu Phe Ser Pro Pro Pro Arg His 
            260                 265                 270         


His Leu Asp Pro His Arg Ile Glu Arg Leu Gly Ala Glu Glu Met Ala 
        275                 280                 285             


Leu Ala Thr His His Pro Ser Ala Phe Asp Arg Val Leu Arg Leu Asn 
    290                 295                 300                 


Pro Met Ala Met Glu Pro Pro Ala Met Asp Phe Ser Arg Arg Leu Arg 
305                 310                 315                 320 


Glu Leu Ala Gly Asn Thr Ser Ser Pro Pro Leu Ser Pro Gly Arg Pro 
                325                 330                 335     


Ser Pro Met Gln Arg Leu Leu Gln Pro Phe Gln Pro Gly Ser Lys Pro 
            340                 345                 350         


Pro Phe Leu Ala Thr Pro Pro Leu Pro Pro Leu Gln Ser Ala Pro Pro 
        355                 360                 365             


Pro Ser Gln Pro Pro Val Lys Ser Lys Ser Cys Glu Phe Cys Gly Lys 
    370                 375                 380                 


Thr Phe Lys Phe Gln Ser Asn Leu Val Val His Arg Arg Ser His Thr 
385                 390                 395                 400 


Gly Glu Lys Pro Tyr Lys Cys Asn Leu Cys Asp His Ala Cys Thr Gln 
                405                 410                 415     


Ala Ser Lys Leu Lys Arg His Met Lys Thr His Met His Lys Ser Ser 
            420                 425                 430         


Pro Met Thr Val Lys Ser Asp Asp Gly Leu Ser Thr Ala Ser Ser Pro 
        435                 440                 445             


Glu Pro Gly Thr Ser Asp Leu Val Gly Ser Ala Ser Ser Ala Leu Lys 
    450                 455                 460                 


Ser Val Val Ala Lys Phe Lys Ser Glu Asn Asp Pro Asn Leu Ile Pro 
465                 470                 475                 480 


Glu Asn Gly Asp Glu Glu Glu Glu Glu Asp Asp Glu Glu Glu Glu Glu 
                485                 490                 495     


Glu Glu Glu Glu Glu Glu Glu Glu Leu Thr Glu Ser Glu Arg Val Asp 
            500                 505                 510         


Tyr Gly Phe Gly Leu Ser Leu Glu Ala Ala Arg His His Glu Asn Ser 
        515                 520                 525             


Ser Arg Gly Ala Val Val Gly Val Gly Asp Glu Ser Arg Ala Leu Pro 
    530                 535                 540                 


Asp Val Met Gln Gly Met Val Leu Ser Ser Met Gln His Phe Ser Glu 
545                 550                 555                 560 


Ala Phe His Gln Val Leu Gly Glu Lys His Lys Arg Gly His Leu Ala 
                565                 570                 575     


Glu Ala Glu Gly His Arg Asp Thr Cys Asp Glu Asp Ser Val Ala Gly 
            580                 585                 590         


Glu Ser Asp Arg Ile Asp Asp Gly Thr Val Asn Gly Arg Gly Cys Ser 
        595                 600                 605             


Pro Gly Glu Ser Ala Ser Gly Gly Leu Ser Lys Lys Leu Leu Leu Gly 
    610                 615                 620                 


Ser Pro Ser Ser Leu Ser Pro Phe Ser Lys Arg Ile Lys Leu Glu Lys 
625                 630                 635                 640 


Glu Phe Asp Leu Pro Pro Ala Ala Met Pro Asn Thr Glu Asn Val Tyr 
                645                 650                 655     


Ser Gln Trp Leu Ala Gly Tyr Ala Ala Ser Arg Gln Leu Lys Asp Pro 
            660                 665                 670         


Phe Leu Ser Phe Gly Asp Ser Arg Gln Ser Pro Phe Ala Ser Ser Ser 
        675                 680                 685             


Glu His Ser Ser Glu Asn Gly Ser Leu Arg Phe Ser Thr Pro Pro Gly 
    690                 695                 700                 


Glu Leu Asp Gly Gly Ile Ser Gly Arg Ser Gly Thr Gly Ser Gly Gly 
705                 710                 715                 720 


Ser Thr Pro His Ile Ser Gly Pro Gly Pro Gly Arg Pro Ser Ser Lys 
                725                 730                 735     


Glu Gly Arg Arg Ser Asp Thr Cys Ser Ser His Thr Pro Ile Arg Arg 
            740                 745                 750         


Ser Thr Gln Arg Ala Gln Asp Val Trp Gln Phe Ser Asp Gly Ser Ser 
        755                 760                 765             


Arg Ala Leu Lys Phe 
    770             


<210>  2787
<211>  243
<212>  PRT
<213>  homo sapiens

<400>  2787

Met Ser Arg Arg Lys Gln Gly Lys Pro Gln His Leu Ser Lys Arg Glu 
1               5                   10                  15      


Phe Ser Pro Glu Pro Leu Glu Ala Ile Leu Thr Asp Asp Glu Pro Asp 
            20                  25                  30          


His Gly Pro Leu Gly Ala Pro Glu Gly Asp His Asp Leu Leu Thr Cys 
        35                  40                  45              


Gly Gln Cys Gln Met Asn Phe Pro Leu Gly Asp Ile Leu Ile Phe Ile 
    50                  55                  60                  


Glu His Lys Arg Lys Gln Cys Asn Gly Ser Leu Cys Leu Glu Lys Ala 
65                  70                  75                  80  


Val Asp Lys Pro Pro Ser Pro Ser Pro Ile Glu Met Lys Lys Ala Ser 
                85                  90                  95      


Asn Pro Val Glu Val Gly Ile Gln Val Thr Pro Glu Asp Asp Asp Cys 
            100                 105                 110         


Leu Ser Thr Ser Ser Arg Gly Ile Cys Pro Lys Gln Glu His Ile Ala 
        115                 120                 125             


Asp Lys Leu Leu His Trp Arg Gly Leu Ser Ser Pro Arg Ser Ala His 
    130                 135                 140                 


Gly Ala Leu Ile Pro Thr Pro Gly Met Ser Ala Glu Tyr Ala Pro Gln 
145                 150                 155                 160 


Gly Ile Cys Lys Asp Glu Pro Ser Ser Tyr Thr Cys Thr Thr Cys Lys 
                165                 170                 175     


Gln Pro Phe Thr Ser Ala Trp Phe Leu Leu Gln His Ala Gln Asn Thr 
            180                 185                 190         


His Gly Leu Arg Ile Tyr Leu Glu Ser Glu His Gly Ser Pro Leu Thr 
        195                 200                 205             


Pro Arg Val Leu His Thr Pro Pro Phe Gly Val Val Pro Arg Glu Leu 
    210                 215                 220                 


Lys Met Cys Gly Ser Phe Arg Met Glu Ala Arg Glu Pro Leu Ser Ser 
225                 230                 235                 240 


Glu Lys Ile 
            


<210>  2788
<211>  888
<212>  PRT
<213>  homo sapiens

<400>  2788

Met Pro Val Arg Arg Gly His Val Ala Pro Gln Asn Thr Phe Leu Asp 
1               5                   10                  15      


Thr Ile Ile Arg Lys Phe Glu Gly Gln Ser Arg Lys Phe Ile Ile Ala 
            20                  25                  30          


Asn Ala Arg Val Glu Asn Cys Ala Val Ile Tyr Cys Asn Asp Gly Phe 
        35                  40                  45              


Cys Glu Leu Cys Gly Tyr Ser Arg Ala Glu Val Met Gln Arg Pro Cys 
    50                  55                  60                  


Thr Cys Asp Phe Leu His Gly Pro Arg Thr Gln Arg Arg Ala Ala Ala 
65                  70                  75                  80  


Gln Ile Ala Gln Ala Leu Leu Gly Ala Glu Glu Arg Lys Val Glu Ile 
                85                  90                  95      


Ala Phe Tyr Arg Lys Asp Gly Ser Cys Phe Leu Cys Leu Val Asp Val 
            100                 105                 110         


Val Pro Val Lys Asn Glu Asp Gly Ala Val Ile Met Phe Ile Leu Asn 
        115                 120                 125             


Phe Glu Val Val Met Glu Lys Asp Met Val Gly Ser Pro Ala His Asp 
    130                 135                 140                 


Thr Asn His Arg Gly Pro Pro Thr Ser Trp Leu Ala Pro Gly Arg Ala 
145                 150                 155                 160 


Lys Thr Phe Arg Leu Lys Leu Pro Ala Leu Leu Ala Leu Thr Ala Arg 
                165                 170                 175     


Glu Ser Ser Val Arg Ser Gly Gly Ala Gly Gly Ala Gly Ala Pro Gly 
            180                 185                 190         


Ala Val Val Val Asp Val Asp Leu Thr Pro Ala Ala Pro Ser Ser Glu 
        195                 200                 205             


Ser Leu Ala Leu Asp Glu Val Thr Ala Met Asp Asn His Val Ala Gly 
    210                 215                 220                 


Leu Gly Pro Ala Glu Glu Arg Arg Ala Leu Val Gly Pro Gly Ser Pro 
225                 230                 235                 240 


Pro Arg Ser Ala Pro Gly Gln Leu Pro Ser Pro Arg Ala His Ser Leu 
                245                 250                 255     


Asn Pro Asp Ala Ser Gly Ser Ser Cys Ser Leu Ala Arg Thr Arg Ser 
            260                 265                 270         


Arg Glu Ser Cys Ala Ser Val Arg Arg Ala Ser Ser Ala Asp Asp Ile 
        275                 280                 285             


Glu Ala Met Arg Ala Gly Val Leu Pro Pro Pro Pro Arg His Ala Ser 
    290                 295                 300                 


Thr Gly Ala Met His Pro Leu Arg Ser Gly Leu Leu Asn Ser Thr Ser 
305                 310                 315                 320 


Asp Ser Asp Leu Val Arg Tyr Arg Thr Ile Ser Lys Ile Pro Gln Ile 
                325                 330                 335     


Thr Leu Asn Phe Val Asp Leu Lys Gly Asp Pro Phe Leu Ala Ser Pro 
            340                 345                 350         


Thr Ser Asp Arg Glu Ile Ile Ala Pro Lys Ile Lys Glu Arg Thr His 
        355                 360                 365             


Asn Val Thr Glu Lys Val Thr Gln Val Leu Ser Leu Gly Ala Asp Val 
    370                 375                 380                 


Leu Pro Glu Tyr Lys Leu Gln Ala Pro Arg Ile His Arg Trp Thr Ile 
385                 390                 395                 400 


Leu His Tyr Ser Pro Phe Lys Ala Val Trp Asp Trp Leu Ile Leu Leu 
                405                 410                 415     


Leu Val Ile Tyr Thr Ala Val Phe Thr Pro Tyr Ser Ala Ala Phe Leu 
            420                 425                 430         


Leu Lys Glu Thr Glu Glu Gly Pro Pro Ala Thr Glu Cys Gly Tyr Ala 
        435                 440                 445             


Cys Gln Pro Leu Ala Val Val Asp Leu Ile Val Asp Ile Met Phe Ile 
    450                 455                 460                 


Val Asp Ile Leu Ile Asn Phe Arg Thr Thr Tyr Val Asn Ala Asn Glu 
465                 470                 475                 480 


Glu Val Val Ser His Pro Gly Arg Ile Ala Val His Tyr Phe Lys Gly 
                485                 490                 495     


Trp Phe Leu Ile Asp Met Val Ala Ala Ile Pro Phe Asp Leu Leu Ile 
            500                 505                 510         


Phe Gly Ser Gly Ser Glu Glu Leu Ile Gly Leu Leu Lys Thr Ala Arg 
        515                 520                 525             


Leu Leu Arg Leu Val Arg Val Ala Arg Lys Leu Asp Arg Tyr Ser Glu 
    530                 535                 540                 


Tyr Gly Ala Ala Val Leu Phe Leu Leu Met Cys Thr Phe Ala Leu Ile 
545                 550                 555                 560 


Ala His Trp Leu Ala Cys Ile Trp Tyr Ala Ile Gly Asn Met Glu Gln 
                565                 570                 575     


Pro His Met Asp Ser Arg Ile Gly Trp Leu His Asn Leu Gly Asp Gln 
            580                 585                 590         


Ile Gly Lys Pro Tyr Asn Ser Ser Gly Leu Gly Gly Pro Ser Ile Lys 
        595                 600                 605             


Asp Lys Tyr Val Thr Ala Leu Tyr Phe Thr Phe Ser Ser Leu Thr Ser 
    610                 615                 620                 


Val Gly Phe Gly Asn Val Ser Pro Asn Thr Asn Ser Glu Lys Ile Phe 
625                 630                 635                 640 


Ser Ile Cys Val Met Leu Ile Gly Ser Leu Met Tyr Ala Ser Ile Phe 
                645                 650                 655     


Gly Asn Val Ser Ala Ile Ile Gln Arg Leu Tyr Ser Gly Thr Ala Arg 
            660                 665                 670         


Tyr His Thr Gln Met Leu Arg Val Arg Glu Phe Ile Arg Phe His Gln 
        675                 680                 685             


Ile Pro Asn Pro Leu Arg Gln Arg Leu Glu Glu Tyr Phe Gln His Ala 
    690                 695                 700                 


Trp Ser Tyr Thr Asn Gly Ile Asp Met Asn Ala Val Leu Lys Gly Phe 
705                 710                 715                 720 


Pro Glu Cys Leu Gln Ala Asp Ile Cys Leu His Leu Asn Arg Ser Leu 
                725                 730                 735     


Leu Gln His Cys Lys Pro Phe Arg Gly Ala Thr Lys Gly Cys Leu Arg 
            740                 745                 750         


Ala Leu Ala Met Lys Phe Lys Thr Thr His Ala Pro Pro Gly Asp Thr 
        755                 760                 765             


Leu Val His Ala Gly Asp Leu Leu Thr Ala Leu Tyr Phe Ile Ser Arg 
    770                 775                 780                 


Gly Ser Ile Glu Ile Leu Arg Gly Asp Val Val Val Ala Ile Leu Gly 
785                 790                 795                 800 


Met Gly Trp Gly Ala Gly Thr Gly Leu Glu Met Pro Ser Ala Ala Ser 
                805                 810                 815     


Arg Gly Ala Ser Leu Leu Asn Met Gln Ser Leu Gly Leu Trp Thr Trp 
            820                 825                 830         


Asp Cys Leu Gln Gly His Trp Ala Pro Leu Ile His Leu Asn Ser Gly 
        835                 840                 845             


Pro Pro Ser Gly Ala Met Glu Arg Ser Pro Thr Trp Gly Glu Ala Ala 
    850                 855                 860                 


Glu Leu Trp Gly Ser His Ile Leu Leu Pro Phe Arg Ile Arg His Lys 
865                 870                 875                 880 


Gln Thr Leu Phe Ala Ser Leu Lys 
                885             


<210>  2789
<211>  181
<212>  PRT
<213>  homo sapiens

<400>  2789

Met His Pro Gly Ser Pro Ser Ala Trp Pro Pro Arg Ala Arg Ala Ala 
1               5                   10                  15      


Leu Arg Leu Trp Leu Gly Cys Val Cys Phe Ala Leu Val Gln Ala Asp 
            20                  25                  30          


Ser Pro Ser Ala Pro Val Asn Val Thr Val Arg His Leu Lys Ala Asn 
        35                  40                  45              


Ser Ala Val Val Ser Trp Asp Val Leu Glu Asp Glu Val Val Ile Gly 
    50                  55                  60                  


Phe Ala Ile Ser Gln Gln Lys Lys Asp Val Arg Met Leu Arg Phe Ile 
65                  70                  75                  80  


Gln Glu Val Asn Thr Thr Thr Arg Ser Cys Ala Leu Trp Asp Leu Glu 
                85                  90                  95      


Glu Asp Thr Glu Tyr Ile Val His Val Gln Ala Ile Ser Ile Gln Gly 
            100                 105                 110         


Gln Ser Pro Ala Ser Glu Pro Val Leu Phe Lys Thr Pro Arg Glu Ala 
        115                 120                 125             


Glu Lys Met Ala Ser Lys Asn Lys Asp Glu Val Thr Met Lys Glu Met 
    130                 135                 140                 


Gly Arg Asn Gln Gln Leu Arg Thr Gly Glu Val Leu Ile Ile Val Val 
145                 150                 155                 160 


Val Leu Phe Met Trp Ala Gly Val Ile Ala Leu Phe Cys Arg Gln Tyr 
                165                 170                 175     


Asp Ile Ile Glu Ala 
            180     


<210>  2790
<211>  212
<212>  PRT
<213>  homo sapiens

<400>  2790

Met His Pro Gly Ser Pro Ser Ala Trp Pro Pro Arg Ala Arg Ala Ala 
1               5                   10                  15      


Leu Arg Leu Trp Leu Gly Cys Val Cys Phe Ala Leu Val Gln Ala Asp 
            20                  25                  30          


Ser Pro Ser Ala Pro Val Asn Val Thr Val Arg His Leu Lys Ala Asn 
        35                  40                  45              


Ser Ala Val Val Ser Trp Asp Val Leu Glu Asp Glu Val Val Ile Gly 
    50                  55                  60                  


Phe Ala Ile Ser Gln Gln Lys Lys Asp Val Arg Met Leu Arg Phe Ile 
65                  70                  75                  80  


Gln Glu Val Asn Thr Thr Thr Arg Ser Cys Ala Leu Trp Asp Leu Glu 
                85                  90                  95      


Glu Asp Thr Glu Tyr Ile Val His Val Gln Ala Ile Ser Ile Gln Gly 
            100                 105                 110         


Gln Ser Pro Ala Ser Glu Pro Val Leu Phe Lys Thr Pro Arg Glu Ala 
        115                 120                 125             


Glu Lys Met Ala Ser Lys Asn Lys Asp Glu Val Thr Met Lys Glu Met 
    130                 135                 140                 


Gly Arg Asn Gln Gln Leu Arg Thr Gly Glu Val Leu Ile Ile Val Val 
145                 150                 155                 160 


Val Leu Phe Met Trp Ala Gly Val Ile Ala Leu Phe Cys Arg Gln Tyr 
                165                 170                 175     


Asp Ile Ile Lys Asp Asn Glu Pro Asn Asn Asn Lys Glu Lys Thr Lys 
            180                 185                 190         


Ser Ala Ser Glu Thr Ser Thr Pro Glu His Gln Gly Gly Gly Leu Leu 
        195                 200                 205             


Arg Ser Lys Ile 
    210         


<210>  2791
<211>  380
<212>  PRT
<213>  homo sapiens

<400>  2791

Met Met Phe Ser Gly Phe Asn Ala Asp Tyr Glu Ala Ser Ser Ser Arg 
1               5                   10                  15      


Cys Ser Ser Ala Ser Pro Ala Gly Asp Ser Leu Ser Tyr Tyr His Ser 
            20                  25                  30          


Pro Ala Asp Ser Phe Ser Ser Met Gly Ser Pro Val Asn Ala Gln Asp 
        35                  40                  45              


Phe Cys Thr Asp Leu Ala Val Ser Ser Ala Asn Phe Ile Pro Thr Val 
    50                  55                  60                  


Thr Ala Ile Ser Thr Ser Pro Asp Leu Gln Trp Leu Val Gln Pro Ala 
65                  70                  75                  80  


Leu Val Ser Ser Val Ala Pro Ser Gln Thr Arg Ala Pro His Pro Phe 
                85                  90                  95      


Gly Val Pro Ala Pro Ser Ala Gly Ala Tyr Ser Arg Ala Gly Val Val 
            100                 105                 110         


Lys Thr Met Thr Gly Gly Arg Ala Gln Ser Ile Gly Arg Arg Gly Lys 
        115                 120                 125             


Val Glu Gln Leu Ser Pro Glu Glu Glu Glu Lys Arg Arg Ile Arg Arg 
    130                 135                 140                 


Glu Arg Asn Lys Met Ala Ala Ala Lys Cys Arg Asn Arg Arg Arg Glu 
145                 150                 155                 160 


Leu Thr Asp Thr Leu Gln Ala Glu Thr Asp Gln Leu Glu Asp Glu Lys 
                165                 170                 175     


Ser Ala Leu Gln Thr Glu Ile Ala Asn Leu Leu Lys Glu Lys Glu Lys 
            180                 185                 190         


Leu Glu Phe Ile Leu Ala Ala His Arg Pro Ala Cys Lys Ile Pro Asp 
        195                 200                 205             


Asp Leu Gly Phe Pro Glu Glu Met Ser Val Ala Ser Leu Asp Leu Thr 
    210                 215                 220                 


Gly Gly Leu Pro Glu Val Ala Thr Pro Glu Ser Glu Glu Ala Phe Thr 
225                 230                 235                 240 


Leu Pro Leu Leu Asn Asp Pro Glu Pro Lys Pro Ser Val Glu Pro Val 
                245                 250                 255     


Lys Ser Ile Ser Ser Met Glu Leu Lys Thr Glu Pro Phe Asp Asp Phe 
            260                 265                 270         


Leu Phe Pro Ala Ser Ser Arg Pro Ser Gly Ser Glu Thr Ala Arg Ser 
        275                 280                 285             


Val Pro Asp Met Asp Leu Ser Gly Ser Phe Tyr Ala Ala Asp Trp Glu 
    290                 295                 300                 


Pro Leu His Ser Gly Ser Leu Gly Met Gly Pro Met Ala Thr Glu Leu 
305                 310                 315                 320 


Glu Pro Leu Cys Thr Pro Val Val Thr Cys Thr Pro Ser Cys Thr Ala 
                325                 330                 335     


Tyr Thr Ser Ser Phe Val Phe Thr Tyr Pro Glu Ala Asp Ser Phe Pro 
            340                 345                 350         


Ser Cys Ala Ala Ala His Arg Lys Gly Ser Ser Ser Asn Glu Pro Ser 
        355                 360                 365             


Ser Asp Ser Leu Ser Ser Pro Thr Leu Leu Ala Leu 
    370                 375                 380 


<210>  2792
<211>  489
<212>  PRT
<213>  homo sapiens

<400>  2792

Met Leu Asp Met Gly Asp Arg Lys Glu Val Lys Met Ile Pro Lys Ser 
1               5                   10                  15      


Ser Phe Ser Ile Asn Ser Leu Val Pro Glu Ala Val Gln Asn Asp Asn 
            20                  25                  30          


His His Ala Ser His Gly His His Asn Ser His His Pro Gln His His 
        35                  40                  45              


His His His His His His His His His Pro Pro Pro Pro Ala Pro Gln 
    50                  55                  60                  


Pro Pro Pro Pro Pro Gln Gln Gln Gln Pro Pro Pro Pro Pro Pro Pro 
65                  70                  75                  80  


Ala Pro Gln Pro Pro Gln Thr Arg Gly Ala Pro Ala Ala Asp Asp Asp 
                85                  90                  95      


Lys Gly Pro Gln Gln Leu Leu Leu Pro Pro Pro Pro Pro Pro Pro Pro 
            100                 105                 110         


Ala Ala Ala Leu Asp Gly Ala Lys Ala Asp Gly Leu Gly Gly Lys Gly 
        115                 120                 125             


Glu Pro Gly Gly Gly Pro Gly Glu Leu Ala Pro Val Gly Pro Asp Glu 
    130                 135                 140                 


Lys Glu Lys Gly Ala Gly Ala Gly Gly Glu Glu Lys Lys Gly Ala Gly 
145                 150                 155                 160 


Glu Gly Gly Lys Asp Gly Glu Gly Gly Lys Glu Gly Glu Lys Lys Asn 
                165                 170                 175     


Gly Lys Tyr Glu Lys Pro Pro Phe Ser Tyr Asn Ala Leu Ile Met Met 
            180                 185                 190         


Ala Ile Arg Gln Ser Pro Glu Lys Arg Leu Thr Leu Asn Gly Ile Tyr 
        195                 200                 205             


Glu Phe Ile Met Lys Asn Phe Pro Tyr Tyr Arg Glu Asn Lys Gln Gly 
    210                 215                 220                 


Trp Gln Asn Ser Ile Arg His Asn Leu Ser Leu Asn Lys Cys Phe Val 
225                 230                 235                 240 


Lys Val Pro Arg His Tyr Asp Asp Pro Gly Lys Gly Asn Tyr Trp Met 
                245                 250                 255     


Leu Asp Pro Ser Ser Asp Asp Val Phe Ile Gly Gly Thr Thr Gly Lys 
            260                 265                 270         


Leu Arg Arg Arg Ser Thr Thr Ser Arg Ala Lys Leu Ala Phe Lys Arg 
        275                 280                 285             


Gly Ala Arg Leu Thr Ser Thr Gly Leu Thr Phe Met Asp Arg Ala Gly 
    290                 295                 300                 


Ser Leu Tyr Trp Pro Met Ser Pro Phe Leu Ser Leu His His Pro Arg 
305                 310                 315                 320 


Ala Ser Ser Thr Leu Ser Tyr Asn Gly Thr Thr Ser Ala Tyr Pro Ser 
                325                 330                 335     


His Pro Met Pro Tyr Ser Ser Val Leu Thr Gln Asn Ser Leu Gly Asn 
            340                 345                 350         


Asn His Ser Phe Ser Thr Ala Asn Gly Leu Ser Val Asp Arg Leu Val 
        355                 360                 365             


Asn Gly Glu Ile Pro Tyr Ala Thr His His Leu Thr Ala Ala Ala Leu 
    370                 375                 380                 


Ala Ala Ser Val Pro Cys Gly Leu Ser Val Pro Cys Ser Gly Thr Tyr 
385                 390                 395                 400 


Ser Leu Asn Pro Cys Ser Val Asn Leu Leu Ala Gly Gln Thr Ser Tyr 
                405                 410                 415     


Phe Phe Pro His Val Pro His Pro Ser Met Thr Ser Gln Ser Ser Thr 
            420                 425                 430         


Ser Met Ser Ala Arg Ala Ala Ser Ser Ser Thr Ser Pro Gln Ala Pro 
        435                 440                 445             


Ser Thr Leu Pro Cys Glu Ser Leu Arg Pro Ser Leu Pro Ser Phe Thr 
    450                 455                 460                 


Thr Gly Leu Ser Gly Gly Leu Ser Asp Tyr Phe Thr His Gln Asn Gln 
465                 470                 475                 480 


Gly Ser Ser Ser Asn Pro Leu Ile His 
                485                 


<210>  2793
<211>  763
<212>  PRT
<213>  homo sapiens

<400>  2793

Met Leu Thr Asp Pro Asp Leu Pro Gln Glu Phe Glu Arg Met Ser Ser 
1               5                   10                  15      


Lys Arg Pro Ala Ser Pro Tyr Gly Glu Ala Asp Gly Glu Val Ala Met 
            20                  25                  30          


Val Thr Ser Arg Gln Lys Val Glu Glu Glu Glu Ser Asp Gly Leu Pro 
        35                  40                  45              


Ala Phe His Leu Pro Leu His Val Ser Phe Pro Asn Lys Pro His Ser 
    50                  55                  60                  


Glu Glu Phe Gln Pro Val Ser Leu Leu Thr Gln Glu Thr Cys Gly His 
65                  70                  75                  80  


Arg Thr Pro Thr Ser Gln His Asn Thr Met Glu Val Asp Gly Asn Lys 
                85                  90                  95      


Val Met Ser Ser Phe Ala Pro His Asn Ser Ser Thr Ser Pro Gln Lys 
            100                 105                 110         


Ala Glu Glu Gly Gly Arg Gln Ser Gly Glu Ser Leu Ser Ser Thr Ala 
        115                 120                 125             


Leu Gly Thr Pro Glu Arg Arg Lys Gly Ser Leu Ala Asp Val Val Asp 
    130                 135                 140                 


Thr Leu Lys Gln Arg Lys Met Glu Glu Leu Ile Lys Asn Glu Pro Glu 
145                 150                 155                 160 


Glu Thr Pro Ser Ile Glu Lys Leu Leu Ser Lys Asp Trp Lys Asp Lys 
                165                 170                 175     


Leu Leu Ala Met Gly Ser Gly Asn Phe Gly Glu Ile Lys Gly Thr Pro 
            180                 185                 190         


Glu Ser Leu Ala Glu Lys Glu Arg Gln Leu Met Gly Met Ile Asn Gln 
        195                 200                 205             


Leu Thr Ser Leu Arg Glu Gln Leu Leu Ala Ala His Asp Glu Gln Lys 
    210                 215                 220                 


Lys Leu Ala Ala Ser Gln Ile Glu Lys Gln Arg Gln Gln Met Glu Leu 
225                 230                 235                 240 


Ala Lys Gln Gln Gln Glu Gln Ile Ala Arg Gln Gln Gln Gln Leu Leu 
                245                 250                 255     


Gln Gln Gln His Lys Ile Asn Leu Leu Gln Gln Gln Ile Gln Val Gln 
            260                 265                 270         


Gly Gln Leu Pro Pro Leu Met Ile Pro Val Phe Pro Pro Asp Gln Arg 
        275                 280                 285             


Thr Leu Ala Ala Ala Ala Gln Gln Gly Phe Leu Leu Pro Pro Gly Phe 
    290                 295                 300                 


Ser Tyr Lys Ala Gly Cys Ser Asp Pro Tyr Pro Val Gln Leu Ile Pro 
305                 310                 315                 320 


Thr Thr Met Ala Ala Ala Ala Ala Ala Thr Pro Gly Leu Gly Pro Leu 
                325                 330                 335     


Gln Leu Gln Gln Leu Tyr Ala Ala Gln Leu Ala Ala Met Gln Val Ser 
            340                 345                 350         


Pro Gly Gly Lys Leu Pro Gly Ile Pro Gln Gly Asn Leu Gly Ala Ala 
        355                 360                 365             


Val Ser Pro Thr Ser Ile His Thr Asp Lys Ser Thr Asn Ser Pro Pro 
    370                 375                 380                 


Pro Lys Ser Lys Asp Glu Val Ala Gln Pro Leu Asn Leu Ser Ala Lys 
385                 390                 395                 400 


Pro Lys Thr Ser Asp Gly Lys Ser Pro Thr Ser Pro Thr Ser Pro His 
                405                 410                 415     


Met Pro Ala Leu Arg Ile Asn Ser Gly Ala Gly Pro Leu Lys Ala Ser 
            420                 425                 430         


Val Pro Ala Ala Leu Ala Ser Pro Ser Ala Arg Val Ser Thr Ile Gly 
        435                 440                 445             


Tyr Leu Asn Asp His Asp Ala Val Thr Lys Ala Ile Gln Glu Ala Arg 
    450                 455                 460                 


Gln Met Lys Glu Gln Leu Arg Arg Glu Gln Gln Val Leu Asp Gly Lys 
465                 470                 475                 480 


Val Ala Val Val Asn Ser Leu Gly Leu Asn Asn Cys Arg Thr Glu Lys 
                485                 490                 495     


Glu Lys Thr Thr Leu Glu Ser Leu Thr Gln Gln Leu Ala Val Lys Gln 
            500                 505                 510         


Asn Glu Glu Gly Lys Phe Ser His Ala Met Met Asp Phe Asn Leu Ser 
        515                 520                 525             


Gly Asp Ser Asp Gly Ser Ala Gly Val Ser Glu Ser Arg Ile Tyr Arg 
    530                 535                 540                 


Glu Ser Arg Gly Arg Gly Ser Asn Glu Pro His Ile Lys Arg Pro Met 
545                 550                 555                 560 


Asn Ala Phe Met Val Trp Ala Lys Asp Glu Arg Arg Lys Ile Leu Gln 
                565                 570                 575     


Ala Phe Pro Asp Met His Asn Ser Asn Ile Ser Lys Ile Leu Gly Ser 
            580                 585                 590         


Arg Trp Lys Ala Met Thr Asn Leu Glu Lys Gln Pro Tyr Tyr Glu Glu 
        595                 600                 605             


Gln Ala Arg Leu Ser Lys Gln His Leu Glu Lys Tyr Pro Asp Tyr Lys 
    610                 615                 620                 


Tyr Lys Pro Arg Pro Lys Arg Thr Cys Leu Val Asp Gly Lys Lys Leu 
625                 630                 635                 640 


Arg Ile Gly Glu Tyr Lys Ala Ile Met Arg Asn Arg Arg Gln Glu Met 
                645                 650                 655     


Arg Gln Tyr Phe Asn Val Gly Gln Gln Ala Gln Ile Pro Ile Ala Thr 
            660                 665                 670         


Ala Gly Val Val Tyr Pro Gly Ala Ile Ala Met Ala Gly Met Pro Ser 
        675                 680                 685             


Pro His Leu Pro Ser Glu His Ser Ser Val Ser Ser Ser Pro Glu Pro 
    690                 695                 700                 


Gly Met Pro Val Ile Gln Ser Thr Tyr Gly Val Lys Gly Glu Glu Pro 
705                 710                 715                 720 


His Ile Lys Glu Glu Ile Gln Ala Glu Asp Ile Asn Gly Glu Ile Tyr 
                725                 730                 735     


Asp Glu Tyr Asp Glu Glu Glu Asp Asp Pro Asp Val Asp Tyr Gly Ser 
            740                 745                 750         


Asp Ser Glu Asn His Ile Ala Gly Gln Ala Asn 
        755                 760             


<210>  2794
<211>  807
<212>  PRT
<213>  homo sapiens

<400>  2794

Met Arg Leu Ser Pro Ala Pro Leu Lys Leu Ser Arg Thr Pro Ala Leu 
1               5                   10                  15      


Leu Ala Leu Ala Leu Pro Leu Ala Ala Ala Leu Ala Phe Ser Asp Glu 
            20                  25                  30          


Thr Leu Asp Lys Val Pro Lys Ser Glu Gly Tyr Cys Ser Arg Ile Leu 
        35                  40                  45              


Arg Ala Gln Gly Thr Arg Arg Glu Gly Tyr Thr Glu Phe Ser Leu Arg 
    50                  55                  60                  


Val Glu Gly Asp Pro Asp Phe Tyr Lys Pro Gly Thr Ser Tyr Arg Val 
65                  70                  75                  80  


Thr Leu Ser Ala Ala Pro Pro Ser Tyr Phe Arg Gly Phe Thr Leu Ile 
                85                  90                  95      


Ala Leu Arg Glu Asn Arg Glu Gly Asp Lys Glu Glu Asp His Ala Gly 
            100                 105                 110         


Thr Phe Gln Ile Ile Asp Glu Glu Glu Thr Gln Phe Met Ser Asn Cys 
        115                 120                 125             


Pro Val Ala Val Thr Glu Ser Thr Pro Arg Arg Arg Thr Arg Ile Gln 
    130                 135                 140                 


Val Phe Trp Ile Ala Pro Pro Ala Gly Thr Gly Cys Val Ile Leu Lys 
145                 150                 155                 160 


Ala Ser Ile Val Gln Lys Arg Ile Ile Tyr Phe Gln Asp Glu Gly Ser 
                165                 170                 175     


Leu Thr Lys Lys Leu Cys Glu Gln Asp Ser Thr Phe Asp Gly Val Thr 
            180                 185                 190         


Asp Lys Pro Ile Leu Asp Cys Cys Ala Cys Gly Thr Ala Lys Tyr Arg 
        195                 200                 205             


Leu Thr Phe Tyr Gly Asn Trp Ser Glu Lys Thr His Pro Lys Asp Tyr 
    210                 215                 220                 


Pro Arg Arg Ala Asn His Trp Ser Ala Ile Ile Gly Gly Ser His Ser 
225                 230                 235                 240 


Lys Asn Tyr Val Leu Trp Glu Tyr Gly Gly Tyr Ala Ser Glu Gly Val 
                245                 250                 255     


Lys Gln Val Ala Glu Leu Gly Ser Pro Val Lys Met Glu Glu Glu Ile 
            260                 265                 270         


Arg Gln Gln Ser Asp Glu Val Leu Thr Val Ile Lys Ala Lys Ala Gln 
        275                 280                 285             


Trp Pro Ala Trp Gln Pro Leu Asn Val Arg Ala Ala Pro Ser Ala Glu 
    290                 295                 300                 


Phe Ser Val Asp Arg Thr Arg His Leu Met Ser Phe Leu Thr Met Met 
305                 310                 315                 320 


Gly Pro Ser Pro Asp Trp Asn Val Gly Leu Ser Ala Glu Asp Leu Cys 
                325                 330                 335     


Thr Lys Glu Cys Gly Trp Val Gln Lys Val Val Gln Asp Leu Ile Pro 
            340                 345                 350         


Trp Asp Ala Gly Thr Asp Ser Gly Val Thr Tyr Glu Ser Pro Asn Lys 
        355                 360                 365             


Pro Thr Ile Pro Gln Glu Lys Ile Arg Pro Leu Thr Ser Leu Asp His 
    370                 375                 380                 


Pro Gln Ser Pro Phe Tyr Asp Pro Glu Gly Gly Ser Ile Thr Gln Val 
385                 390                 395                 400 


Ala Arg Val Val Ile Glu Arg Ile Ala Arg Lys Gly Glu Gln Cys Asn 
                405                 410                 415     


Ile Val Pro Asp Asn Val Asp Asp Ile Val Ala Asp Leu Ala Pro Glu 
            420                 425                 430         


Glu Lys Asp Glu Asp Asp Thr Pro Glu Thr Cys Ile Tyr Ser Asn Trp 
        435                 440                 445             


Ser Pro Trp Ser Ala Cys Ser Ser Ser Thr Cys Asp Lys Gly Lys Arg 
    450                 455                 460                 


Met Arg Gln Arg Met Leu Lys Ala Gln Leu Asp Leu Ser Val Pro Cys 
465                 470                 475                 480 


Pro Asp Thr Gln Asp Phe Gln Pro Cys Met Gly Pro Gly Cys Ser Asp 
                485                 490                 495     


Glu Asp Gly Ser Thr Cys Thr Met Ser Glu Trp Ile Thr Trp Ser Pro 
            500                 505                 510         


Cys Ser Ile Ser Cys Gly Met Gly Met Arg Ser Arg Glu Arg Tyr Val 
        515                 520                 525             


Lys Gln Phe Pro Glu Asp Gly Ser Val Cys Thr Leu Pro Thr Glu Glu 
    530                 535                 540                 


Thr Glu Lys Cys Thr Val Asn Glu Glu Cys Ser Pro Ser Ser Cys Leu 
545                 550                 555                 560 


Met Thr Glu Trp Gly Glu Trp Asp Glu Cys Ser Ala Thr Cys Gly Met 
                565                 570                 575     


Gly Met Lys Lys Arg His Arg Met Ile Lys Met Asn Pro Ala Asp Gly 
            580                 585                 590         


Ser Met Cys Lys Ala Glu Thr Ser Gln Ala Glu Lys Cys Met Met Pro 
        595                 600                 605             


Glu Cys His Thr Ile Pro Cys Leu Leu Ser Pro Trp Ser Glu Trp Ser 
    610                 615                 620                 


Asp Cys Ser Val Thr Cys Gly Lys Gly Met Arg Thr Arg Gln Arg Met 
625                 630                 635                 640 


Leu Lys Ser Leu Ala Glu Leu Gly Asp Cys Asn Glu Asp Leu Glu Gln 
                645                 650                 655     


Val Glu Lys Cys Met Leu Pro Glu Cys Pro Ile Asp Cys Glu Leu Thr 
            660                 665                 670         


Glu Trp Ser Gln Trp Ser Glu Cys Asn Lys Ser Cys Gly Lys Gly His 
        675                 680                 685             


Val Ile Arg Thr Arg Met Ile Gln Met Glu Pro Gln Phe Gly Gly Ala 
    690                 695                 700                 


Pro Cys Pro Glu Thr Val Gln Arg Lys Lys Cys Arg Ile Arg Lys Cys 
705                 710                 715                 720 


Leu Arg Asn Pro Ser Ile Gln Lys Leu Arg Trp Arg Glu Ala Arg Glu 
                725                 730                 735     


Ser Arg Arg Ser Glu Gln Leu Lys Glu Glu Ser Glu Gly Glu Gln Phe 
            740                 745                 750         


Pro Gly Cys Arg Met Arg Pro Trp Thr Ala Trp Ser Glu Cys Thr Lys 
        755                 760                 765             


Leu Cys Gly Gly Gly Ile Gln Glu Arg Tyr Met Thr Val Lys Lys Arg 
    770                 775                 780                 


Phe Lys Ser Ser Gln Phe Thr Ser Cys Lys Asp Lys Lys Glu Ile Arg 
785                 790                 795                 800 


Ala Cys Asn Val His Pro Cys 
                805         


<210>  2795
<211>  127
<212>  PRT
<213>  homo sapiens

<400>  2795

Met Arg Glu Gln Tyr Met Arg Thr Gly Glu Gly Phe Leu Leu Val Phe 
1               5                   10                  15      


Ser Val Thr Asp Arg Gly Ser Phe Glu Glu Ile Tyr Lys Phe Gln Arg 
            20                  25                  30          


Gln Ile Leu Arg Val Lys Asp Arg Asp Glu Phe Pro Met Ile Leu Ile 
        35                  40                  45              


Gly Asn Lys Ala Asp Leu Asp His Gln Arg Gln Val Thr Gln Glu Glu 
    50                  55                  60                  


Gly Gln Gln Leu Ala Arg Gln Leu Lys Val Thr Tyr Met Glu Ala Ser 
65                  70                  75                  80  


Ala Lys Ile Arg Met Asn Val Asp Gln Ala Phe His Glu Leu Val Arg 
                85                  90                  95      


Val Ile Arg Lys Phe Gln Glu Gln Glu Cys Pro Pro Ser Pro Glu Pro 
            100                 105                 110         


Thr Arg Lys Glu Lys Asp Lys Lys Gly Cys His Cys Val Ile Phe 
        115                 120                 125         


<210>  2796
<211>  1687
<212>  PRT
<213>  homo sapiens

<400>  2796

Met Thr Ser Ser Ser Pro Ala Gly Leu Glu Gly Ser Asp Leu Ser Ser 
1               5                   10                  15      


Ile Asn Thr Met Met Ser Ala Val Met Ser Val Gly Lys Val Thr Glu 
            20                  25                  30          


Asn Gly Gly Ser Pro Gln Gly Ile Lys Ser Pro Ser Lys Pro Pro Gly 
        35                  40                  45              


Pro Asn Arg Ile Gly Arg Arg Asn Gln Glu Thr Lys Glu Glu Lys Ser 
    50                  55                  60                  


Ser Tyr Asn Cys Pro Leu Cys Glu Lys Ile Cys Thr Thr Gln His Gln 
65                  70                  75                  80  


Leu Thr Met His Ile Arg Gln His Asn Thr Asp Thr Gly Gly Ala Asp 
                85                  90                  95      


His Ser Cys Ser Ile Cys Gly Lys Ser Leu Ser Ser Ala Ser Ser Leu 
            100                 105                 110         


Asp Arg His Met Leu Val His Ser Gly Glu Arg Pro Tyr Lys Cys Thr 
        115                 120                 125             


Val Cys Gly Gln Ser Phe Thr Thr Asn Gly Asn Met His Arg His Met 
    130                 135                 140                 


Lys Ile His Glu Lys Asp Pro Asn Ser Ala Thr Ala Thr Ala Pro Pro 
145                 150                 155                 160 


Ser Pro Leu Lys Arg Arg Arg Leu Ser Ser Lys Arg Lys Leu Ser His 
                165                 170                 175     


Asp Ala Glu Ser Glu Arg Glu Asp Pro Ala Pro Ala Lys Lys Met Val 
            180                 185                 190         


Glu Asp Gly Gln Ser Gly Asp Leu Glu Lys Lys Ala Asp Glu Val Phe 
        195                 200                 205             


His Cys Pro Val Cys Phe Lys Glu Phe Val Cys Lys Tyr Gly Leu Glu 
    210                 215                 220                 


Thr His Met Glu Thr His Ser Asp Asn Pro Leu Arg Cys Asp Ile Cys 
225                 230                 235                 240 


Cys Val Thr Phe Arg Thr His Arg Gly Leu Leu Arg His Asn Ala Leu 
                245                 250                 255     


Val His Lys Gln Leu Pro Arg Asp Ala Met Gly Arg Pro Phe Ile Gln 
            260                 265                 270         


Asn Asn Pro Ser Ile Pro Ala Gly Phe His Asp Leu Gly Phe Thr Asp 
        275                 280                 285             


Phe Ser Cys Arg Lys Phe Pro Arg Ile Ser Gln Ala Trp Cys Glu Thr 
    290                 295                 300                 


Asn Leu Arg Arg Cys Ile Ser Glu Gln His Arg Phe Val Cys Asp Thr 
305                 310                 315                 320 


Cys Asp Lys Ala Phe Pro Met Leu Cys Ser Leu Ala Leu His Lys Gln 
                325                 330                 335     


Thr His Val Ala Ala Asp Gln Gly Gln Glu Lys Pro Gln Ala Thr Pro 
            340                 345                 350         


Leu Pro Gly Asp Ala Leu Asp Gln Lys Gly Phe Leu Ala Leu Leu Gly 
        355                 360                 365             


Leu Gln His Thr Lys Asp Val Arg Pro Ala Pro Ala Glu Glu Pro Leu 
    370                 375                 380                 


Pro Asp Asp Asn Gln Ala Ile Gln Leu Gln Thr Leu Lys Cys Gln Leu 
385                 390                 395                 400 


Pro Gln Asp Pro Gly Cys Thr Asn Leu Leu Ser Leu Ser Pro Phe Glu 
                405                 410                 415     


Ala Ala Ser Leu Gly Gly Ser Leu Thr Val Leu Pro Ala Thr Lys Asp 
            420                 425                 430         


Ser Ile Lys His Leu Ser Leu Gln Pro Phe Gln Lys Gly Phe Ile Ile 
        435                 440                 445             


Gln Pro Asp Ser Ser Ile Val Val Lys Pro Ile Ser Gly Glu Ser Ala 
    450                 455                 460                 


Ile Glu Leu Ala Asp Ile Gln Gln Ile Leu Lys Met Ala Ala Ser Ala 
465                 470                 475                 480 


Pro Pro Gln Ile Ser Leu Pro Pro Phe Ser Lys Ala Pro Ala Ala Pro 
                485                 490                 495     


Leu Gln Ala Ile Phe Lys His Met Pro Pro Leu Lys Pro Lys Pro Leu 
            500                 505                 510         


Val Thr Pro Arg Thr Val Val Ala Thr Ser Thr Pro Pro Pro Leu Ile 
        515                 520                 525             


Asn Ala Gln Gln Ala Ser Pro Gly Cys Ile Ser Pro Ser Leu Pro Pro 
    530                 535                 540                 


Pro Pro Leu Lys Leu Leu Lys Gly Ser Val Glu Ala Ala Ser Asn Ala 
545                 550                 555                 560 


His Leu Leu Gln Ser Lys Ser Gly Thr Gln Pro His Ala Ala Thr Arg 
                565                 570                 575     


Leu Ser Leu Gln Gln Pro Arg Ala Glu Leu Pro Gly Gln Pro Glu Met 
            580                 585                 590         


Lys Thr Gln Leu Glu Gln Asp Ser Ile Ile Glu Ala Leu Leu Pro Leu 
        595                 600                 605             


Ser Met Glu Ala Lys Ile Lys Gln Glu Ile Thr Glu Gly Glu Leu Lys 
    610                 615                 620                 


Ala Phe Met Thr Ala Pro Gly Gly Lys Lys Thr Pro Ala Met Arg Lys 
625                 630                 635                 640 


Val Leu Tyr Pro Cys Arg Phe Cys Asn Gln Val Phe Ala Phe Ser Gly 
                645                 650                 655     


Val Leu Arg Ala His Val Arg Ser His Leu Gly Ile Ser Pro Tyr Gln 
            660                 665                 670         


Cys Asn Ile Cys Asp Tyr Ile Ala Ala Asp Lys Ala Ala Leu Ile Arg 
        675                 680                 685             


His Leu Arg Thr His Ser Gly Glu Arg Pro Tyr Ile Cys Lys Ile Cys 
    690                 695                 700                 


His Tyr Pro Phe Thr Val Lys Ala Asn Cys Glu Arg His Leu Arg Lys 
705                 710                 715                 720 


Lys His Leu Lys Ala Thr Arg Lys Asp Ile Glu Lys Asn Ile Glu Tyr 
                725                 730                 735     


Val Ser Ser Ser Ala Ala Glu Leu Val Asp Ala Phe Cys Ala Pro Asp 
            740                 745                 750         


Thr Val Cys Arg Leu Cys Gly Glu Asp Leu Lys His Tyr Arg Ala Leu 
        755                 760                 765             


Arg Ile His Met Arg Thr His Cys Gly Arg Gly Leu Gly Gly Gly His 
    770                 775                 780                 


Lys Gly Arg Lys Pro Phe Glu Cys Lys Glu Cys Ser Ala Ala Phe Ala 
785                 790                 795                 800 


Ala Lys Arg Asn Cys Ile His His Ile Leu Lys Gln His Leu His Val 
                805                 810                 815     


Pro Glu Gln Asp Ile Glu Ser Tyr Val Leu Ala Ala Asp Gly Leu Gly 
            820                 825                 830         


Pro Ala Glu Ala Pro Ala Ala Glu Ala Ser Gly Arg Gly Glu Asp Ser 
        835                 840                 845             


Gly Cys Ala Ala Leu Gly Asp Cys Lys Pro Leu Thr Ala Phe Leu Glu 
    850                 855                 860                 


Pro Gln Asn Gly Phe Leu His Arg Gly Pro Thr Gln Pro Pro Pro Pro 
865                 870                 875                 880 


His Val Ser Ile Lys Leu Glu Pro Ala Ser Ser Phe Ala Val Asp Phe 
                885                 890                 895     


Asn Glu Pro Leu Asp Phe Ser Gln Lys Gly Leu Ala Leu Val Gln Val 
            900                 905                 910         


Lys Gln Glu Asn Ile Ser Phe Leu Ser Pro Ser Ser Leu Val Pro Tyr 
        915                 920                 925             


Asp Cys Ser Met Glu Pro Ile Asp Leu Ser Ile Pro Lys Asn Phe Arg 
    930                 935                 940                 


Lys Gly Asp Lys Asp Leu Ala Thr Pro Ser Glu Ala Lys Lys Pro Glu 
945                 950                 955                 960 


Glu Glu Ala Gly Ser Ser Glu Gln Pro Ser Pro Cys Pro Ala Pro Gly 
                965                 970                 975     


Pro Ser Leu Pro Val Thr Leu Gly Pro Ser Gly Ile Leu Glu Ser Pro 
            980                 985                 990         


Met Ala Pro Ala Pro Ala Ala Thr  Pro Glu Pro Pro Ala  Gln Pro Leu 
        995                 1000                 1005             


Gln Gly  Pro Val Gln Leu Ala  Val Pro Ile Tyr Ser  Ser Ala Leu 
    1010                 1015                 1020             


Val Ser  Ser Pro Pro Leu Val  Gly Ser Ser Ala Leu  Leu Ser Gly 
    1025                 1030                 1035             


Thr Ala  Leu Leu Arg Pro Leu  Arg Pro Lys Pro Pro  Leu Leu Leu 
    1040                 1045                 1050             


Pro Lys  Pro Pro Val Thr Glu  Glu Leu Pro Pro Leu  Ala Ser Ile 
    1055                 1060                 1065             


Ala Gln  Ile Ile Ser Ser Val  Ser Ser Ala Pro Thr  Leu Leu Lys 
    1070                 1075                 1080             


Thr Lys  Val Ala Asp Pro Gly  Pro Ala Ser Thr Gly  Ser Asn Thr 
    1085                 1090                 1095             


Thr Ala  Ser Asp Ser Leu Gly  Gly Ser Val Pro Lys  Ala Ala Thr 
    1100                 1105                 1110             


Thr Ala  Thr Pro Ala Ala Thr  Thr Ser Pro Lys Glu  Ser Ser Glu 
    1115                 1120                 1125             


Pro Pro  Ala Pro Ala Ser Ser  Pro Glu Ala Ala Ser  Pro Thr Glu 
    1130                 1135                 1140             


Gln Gly  Pro Ala Gly Thr Ser  Lys Lys Arg Gly Arg  Lys Arg Gly 
    1145                 1150                 1155             


Met Arg  Ser Arg Pro Arg Ala  Asn Ser Gly Gly Val  Asp Leu Asp 
    1160                 1165                 1170             


Ser Ser  Gly Glu Phe Ala Ser  Ile Glu Lys Met Leu  Ala Thr Thr 
    1175                 1180                 1185             


Asp Thr  Asn Lys Phe Ser Pro  Phe Leu Gln Thr Ala  Glu Asp Asn 
    1190                 1195                 1200             


Thr Gln  Asp Glu Val Ala Gly  Ala Pro Ala Asp His  His Gly Pro 
    1205                 1210                 1215             


Ser Asp  Glu Glu Gln Gly Ser  Pro Pro Glu Asp Lys  Leu Leu Arg 
    1220                 1225                 1230             


Ala Lys  Arg Asn Ser Tyr Thr  Asn Cys Leu Gln Lys  Ile Thr Cys 
    1235                 1240                 1245             


Pro His  Cys Pro Arg Val Phe  Pro Trp Ala Ser Ser  Leu Gln Arg 
    1250                 1255                 1260             


His Met  Leu Thr His Thr Asp  Ser Gln Ser Asp Ala  Glu Thr Ala 
    1265                 1270                 1275             


Ala Ala  Ala Gly Glu Val Leu  Asp Leu Thr Ser Arg  Asp Arg Glu 
    1280                 1285                 1290             


Gln Pro  Ser Glu Gly Ala Thr  Glu Leu Arg Gln Val  Ala Gly Asp 
    1295                 1300                 1305             


Ala Pro  Val Glu Gln Ala Thr  Ala Glu Thr Ala Ser  Pro Val His 
    1310                 1315                 1320             


Arg Glu  Glu His Gly Arg Gly  Glu Ser His Glu Pro  Glu Glu Glu 
    1325                 1330                 1335             


His Gly  Thr Glu Glu Ser Thr  Gly Asp Ala Asp Gly  Ala Glu Glu 
    1340                 1345                 1350             


Asp Ala  Ser Ser Asn Gln Ser  Leu Asp Leu Asp Phe  Ala Thr Lys 
    1355                 1360                 1365             


Leu Met  Asp Phe Lys Leu Ala  Glu Gly Asp Gly Glu  Ala Gly Ala 
    1370                 1375                 1380             


Gly Gly  Ala Ala Ser Gln Glu  Gln Lys Leu Ala Cys  Asp Thr Cys 
    1385                 1390                 1395             


Gly Lys  Ser Phe Lys Phe Leu  Gly Thr Leu Ser Arg  His Arg Lys 
    1400                 1405                 1410             


Ala His  Gly Arg Gln Glu Pro  Lys Asp Glu Lys Gly  Asp Gly Ala 
    1415                 1420                 1425             


Ser Thr  Ala Glu Glu Gly Pro  Gln Pro Ala Pro Glu  Gln Glu Glu 
    1430                 1435                 1440             


Lys Pro  Pro Glu Thr Pro Ala  Glu Val Val Glu Ser  Ala Pro Gly 
    1445                 1450                 1455             


Ala Gly  Glu Ala Pro Ala Glu  Lys Leu Ala Glu Glu  Thr Glu Gly 
    1460                 1465                 1470             


Pro Ser  Asp Gly Glu Ser Ala  Ala Glu Lys Arg Ser  Ser Glu Lys 
    1475                 1480                 1485             


Ser Asp  Asp Asp Lys Lys Pro  Lys Thr Asp Ser Pro  Lys Ser Val 
    1490                 1495                 1500             


Ala Ser  Lys Ala Asp Lys Arg  Lys Lys Val Cys Ser  Val Cys Asn 
    1505                 1510                 1515             


Lys Arg  Phe Trp Ser Leu Gln  Asp Leu Thr Arg His  Met Arg Ser 
    1520                 1525                 1530             


His Thr  Gly Glu Arg Pro Tyr  Lys Cys Gln Thr Cys  Glu Arg Thr 
    1535                 1540                 1545             


Phe Thr  Leu Lys His Ser Leu  Val Arg His Gln Arg  Ile His Gln 
    1550                 1555                 1560             


Lys Ala  Arg His Ala Lys His  His Gly Lys Asp Ser  Asp Lys Glu 
    1565                 1570                 1575             


Glu Arg  Gly Glu Glu Asp Ser  Glu Asn Glu Ser Thr  His Ser Gly 
    1580                 1585                 1590             


Asn Asn  Ala Val Ser Glu Asn  Glu Ala Glu Leu Ala  Pro Asn Ala 
    1595                 1600                 1605             


Ser Asn  His Met Ala Val Thr  Arg Ser Arg Lys Glu  Gly Leu Ala 
    1610                 1615                 1620             


Ser Ala  Thr Lys Asp Cys Ser  His Arg Glu Glu Lys  Val Thr Ala 
    1625                 1630                 1635             


Gly Trp  Pro Ser Glu Pro Gly  Gln Gly Asp Leu Asn  Pro Glu Ser 
    1640                 1645                 1650             


Pro Ala  Ala Leu Gly Gln Asp  Leu Leu Glu Pro Arg  Ser Lys Arg 
    1655                 1660                 1665             


Pro Ala  His Pro Ile Leu Ala  Thr Ala Asp Gly Ala  Ser Gln Leu 
    1670                 1675                 1680             


Val Gly  Met Glu 
    1685         


<210>  2797
<211>  370
<212>  PRT
<213>  homo sapiens

<400>  2797

Met Gly Asp Arg Arg Phe Ile Asp Phe Gln Phe Gln Asp Ser Asn Ser 
1               5                   10                  15      


Ser Leu Arg Pro Arg Leu Gly Asn Ala Thr Ala Asn Asn Thr Cys Ile 
            20                  25                  30          


Val Asp Asp Ser Phe Lys Tyr Asn Leu Asn Gly Ala Val Tyr Ser Val 
        35                  40                  45              


Val Phe Ile Leu Gly Leu Ile Thr Asn Ser Val Ser Leu Phe Val Phe 
    50                  55                  60                  


Cys Phe Arg Met Lys Met Arg Ser Glu Thr Ala Ile Phe Ile Thr Asn 
65                  70                  75                  80  


Leu Ala Val Ser Asp Leu Leu Phe Val Cys Thr Leu Pro Phe Lys Ile 
                85                  90                  95      


Phe Tyr Asn Phe Asn Arg His Trp Pro Phe Gly Asp Thr Leu Cys Lys 
            100                 105                 110         


Ile Ser Gly Thr Ala Phe Leu Thr Asn Ile Tyr Gly Ser Met Leu Phe 
        115                 120                 125             


Leu Thr Cys Ile Ser Val Asp Arg Phe Leu Ala Ile Val Tyr Pro Phe 
    130                 135                 140                 


Arg Ser Arg Thr Ile Arg Thr Arg Arg Asn Ser Ala Ile Val Cys Ala 
145                 150                 155                 160 


Gly Val Trp Ile Leu Val Leu Ser Gly Gly Ile Ser Ala Ser Leu Phe 
                165                 170                 175     


Ser Thr Thr Asn Val Asn Asn Ala Thr Thr Thr Cys Phe Glu Gly Phe 
            180                 185                 190         


Ser Lys Arg Val Trp Lys Thr Tyr Leu Ser Lys Ile Thr Ile Phe Ile 
        195                 200                 205             


Glu Val Val Gly Phe Ile Ile Pro Leu Ile Leu Asn Val Ser Cys Ser 
    210                 215                 220                 


Ser Val Val Leu Arg Thr Leu Arg Lys Pro Ala Thr Leu Ser Gln Ile 
225                 230                 235                 240 


Gly Thr Asn Lys Lys Lys Val Leu Lys Met Ile Thr Val His Met Ala 
                245                 250                 255     


Val Phe Val Val Cys Phe Val Pro Tyr Asn Ser Val Leu Phe Leu Tyr 
            260                 265                 270         


Ala Leu Val Arg Ser Gln Ala Ile Thr Asn Cys Phe Leu Glu Arg Phe 
        275                 280                 285             


Ala Lys Ile Met Tyr Pro Ile Thr Leu Cys Leu Ala Thr Leu Asn Cys 
    290                 295                 300                 


Cys Phe Asp Pro Phe Ile Tyr Tyr Phe Thr Leu Glu Ser Phe Gln Lys 
305                 310                 315                 320 


Ser Phe Tyr Ile Asn Ala His Ile Arg Met Glu Ser Leu Phe Lys Thr 
                325                 330                 335     


Glu Thr Pro Leu Thr Thr Lys Pro Ser Leu Pro Ala Ile Gln Glu Glu 
            340                 345                 350         


Val Ser Asp Gln Thr Thr Asn Asn Gly Gly Glu Leu Met Leu Glu Ser 
        355                 360                 365             


Thr Phe 
    370 


<210>  2798
<211>  983
<212>  PRT
<213>  homo sapiens

<400>  2798

Met Asp Cys Gln Leu Ser Ile Leu Leu Leu Leu Ser Cys Ser Val Leu 
1               5                   10                  15      


Asp Ser Phe Gly Glu Leu Ile Pro Gln Pro Ser Asn Glu Val Asn Leu 
            20                  25                  30          


Leu Asp Ser Lys Thr Ile Gln Gly Glu Leu Gly Trp Ile Ser Tyr Pro 
        35                  40                  45              


Ser His Gly Trp Glu Glu Ile Ser Gly Val Asp Glu His Tyr Thr Pro 
    50                  55                  60                  


Ile Arg Thr Tyr Gln Val Cys Asn Val Met Asp His Ser Gln Asn Asn 
65                  70                  75                  80  


Trp Leu Arg Thr Asn Trp Val Pro Arg Asn Ser Ala Gln Lys Ile Tyr 
                85                  90                  95      


Val Glu Leu Lys Phe Thr Leu Arg Asp Cys Asn Ser Ile Pro Leu Val 
            100                 105                 110         


Leu Gly Thr Cys Lys Glu Thr Phe Asn Leu Tyr Tyr Met Glu Ser Asp 
        115                 120                 125             


Asp Asp His Gly Val Lys Phe Arg Glu His Gln Phe Thr Lys Ile Asp 
    130                 135                 140                 


Thr Ile Ala Ala Asp Glu Ser Phe Thr Gln Met Asp Leu Gly Asp Arg 
145                 150                 155                 160 


Ile Leu Lys Leu Asn Thr Glu Ile Arg Glu Val Gly Pro Val Asn Lys 
                165                 170                 175     


Lys Gly Phe Tyr Leu Ala Phe Gln Asp Val Gly Ala Cys Val Ala Leu 
            180                 185                 190         


Val Ser Val Arg Val Tyr Phe Lys Lys Cys Pro Phe Thr Val Lys Asn 
        195                 200                 205             


Leu Ala Met Phe Pro Asp Thr Val Pro Met Asp Ser Gln Ser Leu Val 
    210                 215                 220                 


Glu Val Arg Gly Ser Cys Val Asn Asn Ser Lys Glu Glu Asp Pro Pro 
225                 230                 235                 240 


Arg Met Tyr Cys Ser Thr Glu Gly Glu Trp Leu Val Pro Ile Gly Lys 
                245                 250                 255     


Cys Ser Cys Asn Ala Gly Tyr Glu Glu Arg Gly Phe Met Cys Gln Ala 
            260                 265                 270         


Cys Arg Pro Gly Phe Tyr Lys Ala Leu Asp Gly Asn Met Lys Cys Ala 
        275                 280                 285             


Lys Cys Pro Pro His Ser Ser Thr Gln Glu Asp Gly Ser Met Asn Cys 
    290                 295                 300                 


Arg Cys Glu Asn Asn Tyr Phe Arg Ala Asp Lys Asp Pro Pro Ser Met 
305                 310                 315                 320 


Ala Cys Thr Arg Pro Pro Ser Ser Pro Arg Asn Val Ile Ser Asn Ile 
                325                 330                 335     


Asn Glu Thr Ser Val Ile Leu Asp Trp Ser Trp Pro Leu Asp Thr Gly 
            340                 345                 350         


Gly Arg Lys Asp Val Thr Phe Asn Ile Ile Cys Lys Lys Cys Gly Trp 
        355                 360                 365             


Asn Ile Lys Gln Cys Glu Pro Cys Ser Pro Asn Val Arg Phe Leu Pro 
    370                 375                 380                 


Arg Gln Phe Gly Leu Thr Asn Thr Thr Val Thr Val Thr Asp Leu Leu 
385                 390                 395                 400 


Ala His Thr Asn Tyr Thr Phe Glu Ile Asp Ala Val Asn Gly Val Ser 
                405                 410                 415     


Glu Leu Ser Ser Pro Pro Arg Gln Phe Ala Ala Val Ser Ile Thr Thr 
            420                 425                 430         


Asn Gln Ala Ala Pro Ser Pro Val Leu Thr Ile Lys Lys Asp Arg Thr 
        435                 440                 445             


Ser Arg Asn Ser Ile Ser Leu Ser Trp Gln Glu Pro Glu His Pro Asn 
    450                 455                 460                 


Gly Ile Ile Leu Asp Tyr Glu Val Lys Tyr Tyr Glu Lys Gln Glu Gln 
465                 470                 475                 480 


Glu Thr Ser Tyr Thr Ile Leu Arg Ala Arg Gly Thr Asn Val Thr Ile 
                485                 490                 495     


Ser Ser Leu Lys Pro Asp Thr Ile Tyr Val Phe Gln Ile Arg Ala Arg 
            500                 505                 510         


Thr Ala Ala Gly Tyr Gly Thr Asn Ser Arg Lys Phe Glu Phe Glu Thr 
        515                 520                 525             


Ser Pro Asp Ser Phe Ser Ile Ser Gly Glu Ser Ser Gln Val Val Met 
    530                 535                 540                 


Ile Ala Ile Ser Ala Ala Val Ala Ile Ile Leu Leu Thr Val Val Ile 
545                 550                 555                 560 


Tyr Val Leu Ile Gly Arg Phe Cys Gly Tyr Lys Ser Lys His Gly Ala 
                565                 570                 575     


Asp Glu Lys Arg Leu His Phe Gly Asn Gly His Leu Lys Leu Pro Gly 
            580                 585                 590         


Leu Arg Thr Tyr Val Asp Pro His Thr Tyr Glu Asp Pro Thr Gln Ala 
        595                 600                 605             


Val His Glu Phe Ala Lys Glu Leu Asp Ala Thr Asn Ile Ser Ile Asp 
    610                 615                 620                 


Lys Val Val Gly Ala Gly Glu Phe Gly Glu Val Cys Ser Gly Arg Leu 
625                 630                 635                 640 


Lys Leu Pro Ser Lys Lys Glu Ile Ser Val Ala Ile Lys Thr Leu Lys 
                645                 650                 655     


Val Gly Tyr Thr Glu Lys Gln Arg Arg Asp Phe Leu Gly Glu Ala Ser 
            660                 665                 670         


Ile Met Gly Gln Phe Asp His Pro Asn Ile Ile Arg Leu Glu Gly Val 
        675                 680                 685             


Val Thr Lys Ser Lys Pro Val Met Ile Val Thr Glu Tyr Met Glu Asn 
    690                 695                 700                 


Gly Ser Leu Asp Ser Phe Leu Arg Lys His Asp Ala Gln Phe Thr Val 
705                 710                 715                 720 


Ile Gln Leu Val Gly Met Leu Arg Gly Ile Ala Ser Gly Met Lys Tyr 
                725                 730                 735     


Leu Ser Asp Met Gly Tyr Val His Arg Asp Leu Ala Ala Arg Asn Ile 
            740                 745                 750         


Leu Ile Asn Ser Asn Leu Val Cys Lys Val Ser Asp Phe Gly Leu Ser 
        755                 760                 765             


Arg Val Leu Glu Asp Asp Pro Glu Ala Ala Tyr Thr Thr Arg Gly Gly 
    770                 775                 780                 


Lys Ile Pro Ile Arg Trp Thr Ser Pro Glu Ala Ile Ala Tyr Arg Lys 
785                 790                 795                 800 


Phe Thr Ser Ala Ser Asp Val Trp Ser Tyr Gly Ile Val Leu Trp Glu 
                805                 810                 815     


Val Met Ser Tyr Gly Glu Arg Pro Tyr Trp Glu Met Ser Asn Gln Asp 
            820                 825                 830         


Val Ile Lys Ala Val Asp Glu Gly Tyr Arg Leu Pro Pro Pro Met Asp 
        835                 840                 845             


Cys Pro Ala Ala Leu Tyr Gln Leu Met Leu Asp Cys Trp Gln Lys Asp 
    850                 855                 860                 


Arg Asn Asn Arg Pro Lys Phe Glu Gln Ile Val Ser Ile Leu Asp Lys 
865                 870                 875                 880 


Leu Ile Arg Asn Pro Gly Ser Leu Lys Ile Ile Thr Ser Ala Ala Ala 
                885                 890                 895     


Arg Pro Ser Asn Leu Leu Leu Asp Gln Ser Asn Val Asp Ile Thr Thr 
            900                 905                 910         


Phe Arg Thr Thr Gly Asp Trp Leu Asn Gly Val Trp Thr Ala His Cys 
        915                 920                 925             


Lys Glu Ile Phe Thr Gly Val Glu Tyr Ser Ser Cys Asp Thr Ile Ala 
    930                 935                 940                 


Lys Ile Ser Thr Asp Asp Met Lys Lys Val Gly Val Thr Val Val Gly 
945                 950                 955                 960 


Pro Gln Lys Lys Ile Ile Ser Ser Ile Lys Ala Leu Glu Thr Gln Ser 
                965                 970                 975     


Lys Asn Gly Pro Val Pro Val 
            980             


<210>  2799
<211>  233
<212>  PRT
<213>  homo sapiens

<400>  2799

Met Trp Ser Gly Leu Leu Pro Pro Gly Leu Asn Glu Ser Asp Ala Glu 
1               5                   10                  15      


Ser Asn Ser Glu Asp Glu Ala Thr Leu Glu Asn Ser Gly Leu Asn Leu 
            20                  25                  30          


Gln Glu Asp Lys Glu Asp Glu Ser Ile Arg Lys Thr Glu Ile Ile Asp 
        35                  40                  45              


Phe Ser Thr Asp Glu Pro Lys Thr Glu Thr Glu Ser Asn Val Asn Ala 
    50                  55                  60                  


Tyr Glu Glu Cys Pro Ser Gly Ile Pro Ile Asp Met Trp Asn Lys Phe 
65                  70                  75                  80  


Gln Glu Leu His Lys Lys His Ser Glu Gln Lys Ser Thr Thr Ser Arg 
                85                  90                  95      


Phe Arg Gly Lys Arg Arg Lys Arg Ser Arg Lys Asp Lys Leu Lys Asn 
            100                 105                 110         


Glu Lys Glu Leu His Ser Glu Pro Ser Ser Asn Glu Thr Gln Trp Lys 
        115                 120                 125             


Glu Leu Thr Gln Tyr Phe Gly Val Asn Asp Arg Phe Asp Pro Pro Val 
    130                 135                 140                 


Lys Arg Lys Lys Val Glu Lys Ser Gly Leu Glu Lys Arg Ile Asp Gln 
145                 150                 155                 160 


Ala Val Glu Glu Trp Asn Ile Glu Lys Ala Glu Glu Leu Ser Asn Gln 
                165                 170                 175     


Leu Ala Thr Arg Glu Leu Gly Val Lys Ile Ala Lys Ala Val Ala Cys 
            180                 185                 190         


His Asn Phe Val Lys Ala Lys Lys Glu Val Glu Asn Ser Gln Ala Ala 
        195                 200                 205             


Arg Lys Lys Lys Lys Leu Ala Trp Gly Phe Glu Ala Lys Lys Arg Trp 
    210                 215                 220                 


Glu Thr Lys Ser Asn Met Gly Tyr Met 
225                 230             


<210>  2800
<211>  731
<212>  PRT
<213>  homo sapiens

<400>  2800

Met Val Val Glu His Pro Glu Phe Leu Lys Ala Gly Lys Glu Pro Gly 
1               5                   10                  15      


Leu Gln Ile Trp Arg Val Glu Lys Phe Asp Leu Val Pro Val Pro Thr 
            20                  25                  30          


Asn Leu Tyr Gly Asp Phe Phe Thr Gly Asp Ala Tyr Val Ile Leu Lys 
        35                  40                  45              


Thr Val Gln Leu Arg Asn Gly Asn Leu Gln Tyr Asp Leu His Tyr Trp 
    50                  55                  60                  


Leu Gly Asn Glu Cys Ser Gln Asp Glu Ser Gly Ala Ala Ala Ile Phe 
65                  70                  75                  80  


Thr Val Gln Leu Asp Asp Tyr Leu Asn Gly Arg Ala Val Gln His Arg 
                85                  90                  95      


Glu Val Gln Gly Phe Glu Ser Ala Thr Phe Leu Gly Tyr Phe Lys Ser 
            100                 105                 110         


Gly Leu Lys Tyr Lys Lys Gly Gly Val Ala Ser Gly Phe Lys His Val 
        115                 120                 125             


Val Pro Asn Glu Val Val Val Gln Arg Leu Phe Gln Val Lys Gly Arg 
    130                 135                 140                 


Arg Val Val Arg Ala Thr Glu Val Pro Val Ser Trp Glu Ser Phe Asn 
145                 150                 155                 160 


Asn Gly Asp Cys Phe Ile Leu Asp Leu Gly Asn Asn Ile His Gln Trp 
                165                 170                 175     


Cys Gly Ser Asn Ser Asn Arg Tyr Glu Arg Leu Lys Ala Thr Gln Val 
            180                 185                 190         


Ser Lys Gly Ile Arg Asp Asn Glu Arg Ser Gly Arg Ala Arg Val His 
        195                 200                 205             


Val Ser Glu Glu Gly Thr Glu Pro Glu Ala Met Leu Gln Val Leu Gly 
    210                 215                 220                 


Pro Lys Pro Ala Leu Pro Ala Gly Thr Glu Asp Thr Ala Lys Glu Asp 
225                 230                 235                 240 


Ala Ala Asn Arg Lys Leu Ala Lys Leu Tyr Lys Val Ser Asn Gly Ala 
                245                 250                 255     


Gly Thr Met Ser Val Ser Leu Val Ala Asp Glu Asn Pro Phe Ala Gln 
            260                 265                 270         


Gly Ala Leu Lys Ser Glu Asp Cys Phe Ile Leu Asp His Gly Lys Asp 
        275                 280                 285             


Gly Lys Ile Phe Val Trp Lys Gly Lys Gln Ala Asn Thr Glu Glu Arg 
    290                 295                 300                 


Lys Ala Ala Leu Lys Thr Ala Ser Asp Phe Ile Thr Lys Met Asp Tyr 
305                 310                 315                 320 


Pro Lys Gln Thr Gln Val Ser Val Leu Pro Glu Gly Gly Glu Thr Pro 
                325                 330                 335     


Leu Phe Lys Gln Phe Phe Lys Asn Trp Arg Asp Pro Asp Gln Thr Asp 
            340                 345                 350         


Gly Leu Gly Leu Ser Tyr Leu Ser Ser His Ile Ala Asn Val Glu Arg 
        355                 360                 365             


Val Pro Phe Asp Ala Ala Thr Leu His Thr Ser Thr Ala Met Ala Ala 
    370                 375                 380                 


Gln His Gly Met Asp Asp Asp Gly Thr Gly Gln Lys Gln Ile Trp Arg 
385                 390                 395                 400 


Ile Glu Gly Ser Asn Lys Val Pro Val Asp Pro Ala Thr Tyr Gly Gln 
                405                 410                 415     


Phe Tyr Gly Gly Asp Ser Tyr Ile Ile Leu Tyr Asn Tyr Arg His Gly 
            420                 425                 430         


Gly Arg Gln Gly Gln Ile Ile Tyr Asn Trp Gln Gly Ala Gln Ser Thr 
        435                 440                 445             


Gln Asp Glu Val Ala Ala Ser Ala Ile Leu Thr Ala Gln Leu Asp Glu 
    450                 455                 460                 


Glu Leu Gly Gly Thr Pro Val Gln Ser Arg Val Val Gln Gly Lys Glu 
465                 470                 475                 480 


Pro Ala His Leu Met Ser Leu Phe Gly Gly Lys Pro Met Ile Ile Tyr 
                485                 490                 495     


Lys Gly Gly Thr Ser Arg Glu Gly Gly Gln Thr Ala Pro Ala Ser Thr 
            500                 505                 510         


Arg Leu Phe Gln Val Arg Ala Asn Ser Ala Gly Ala Thr Arg Ala Val 
        515                 520                 525             


Glu Val Leu Pro Lys Ala Gly Ala Leu Asn Ser Asn Asp Ala Phe Val 
    530                 535                 540                 


Leu Lys Thr Pro Ser Ala Ala Tyr Leu Trp Val Gly Thr Gly Ala Ser 
545                 550                 555                 560 


Glu Ala Glu Lys Thr Gly Ala Gln Glu Leu Leu Arg Val Leu Arg Ala 
                565                 570                 575     


Gln Pro Val Gln Val Ala Glu Gly Ser Glu Pro Asp Gly Phe Trp Glu 
            580                 585                 590         


Ala Leu Gly Gly Lys Ala Ala Tyr Arg Thr Ser Pro Arg Leu Lys Asp 
        595                 600                 605             


Lys Lys Met Asp Ala His Pro Pro Arg Leu Phe Ala Cys Ser Asn Lys 
    610                 615                 620                 


Ile Gly Arg Phe Val Ile Glu Glu Val Pro Gly Glu Leu Met Gln Glu 
625                 630                 635                 640 


Asp Leu Ala Thr Asp Asp Val Met Leu Leu Asp Thr Trp Asp Gln Val 
                645                 650                 655     


Phe Val Trp Val Gly Lys Asp Ser Gln Glu Glu Glu Lys Thr Glu Ala 
            660                 665                 670         


Leu Thr Ser Ala Lys Arg Tyr Ile Glu Thr Asp Pro Ala Asn Arg Asp 
        675                 680                 685             


Arg Arg Thr Pro Ile Thr Val Val Lys Gln Gly Phe Glu Pro Pro Ser 
    690                 695                 700                 


Phe Val Gly Trp Phe Leu Gly Trp Asp Asp Asp Tyr Trp Ser Val Asp 
705                 710                 715                 720 


Pro Leu Asp Arg Ala Met Ala Glu Leu Ala Ala 
                725                 730     


<210>  2801
<211>  1190
<212>  PRT
<213>  homo sapiens

<400>  2801

Met Lys Gln Pro Ile Met Ala Asp Gly Pro Arg Cys Lys Arg Arg Lys 
1               5                   10                  15      


Gln Ala Asn Pro Arg Arg Lys Asn Val Val Asn Tyr Asp Asn Val Val 
            20                  25                  30          


Asp Thr Gly Ser Glu Thr Asp Glu Glu Asp Lys Leu His Ile Ala Glu 
        35                  40                  45              


Asp Asp Gly Ile Ala Asn Pro Leu Asp Gln Glu Thr Ser Pro Ala Ser 
    50                  55                  60                  


Val Pro Asn His Glu Ser Ser Pro His Val Ser Gln Ala Leu Leu Pro 
65                  70                  75                  80  


Arg Glu Glu Glu Glu Asp Glu Ile Arg Glu Gly Gly Val Glu His Pro 
                85                  90                  95      


Trp His Asn Asn Glu Ile Leu Gln Ala Ser Val Asp Gly Pro Val Lys 
            100                 105                 110         


Asn Ala Asn Cys Thr Ser Asp Phe Glu Glu Tyr Phe Ala Lys Arg Lys 
        115                 120                 125             


Leu Glu Glu Arg Asp Gly His Ala Val Ser Ile Glu Glu Tyr Leu Gln 
    130                 135                 140                 


Arg Ser Asp Thr Ala Ile Ile Tyr Pro Glu Ala Pro Glu Glu Leu Ser 
145                 150                 155                 160 


Arg Leu Gly Thr Pro Glu Ala Asn Gly Gln Glu Glu Asn Asp Leu Pro 
                165                 170                 175     


Pro Gly Thr Pro Asp Ala Phe Ala Gln Leu Leu Thr Cys Pro Tyr Cys 
            180                 185                 190         


Asp Arg Gly Tyr Lys Arg Leu Thr Ser Leu Lys Glu His Ile Lys Tyr 
        195                 200                 205             


Arg His Glu Lys Asn Glu Glu Asn Phe Ser Cys Pro Leu Cys Ser Tyr 
    210                 215                 220                 


Thr Phe Ala Tyr Arg Thr Gln Leu Glu Arg His Met Val Thr His Lys 
225                 230                 235                 240 


Pro Gly Thr Asp Gln His Gln Met Leu Thr Gln Gly Ala Gly Asn Arg 
                245                 250                 255     


Lys Phe Lys Cys Thr Glu Cys Gly Lys Ala Phe Lys Tyr Lys His His 
            260                 265                 270         


Leu Lys Glu His Leu Arg Ile His Ser Gly Glu Lys Pro Tyr Glu Cys 
        275                 280                 285             


Pro Asn Cys Lys Lys Arg Phe Ser His Ser Gly Ser Tyr Ser Ser His 
    290                 295                 300                 


Ile Ser Ser Lys Lys Cys Ile Gly Leu Ile Ser Val Asn Gly Arg Met 
305                 310                 315                 320 


Arg Asn Asn Ile Lys Thr Gly Ser Ser Pro Asn Ser Val Ser Ser Ser 
                325                 330                 335     


Pro Thr Asn Ser Ala Ile Thr Gln Leu Arg Asn Lys Leu Glu Asn Gly 
            340                 345                 350         


Lys Pro Leu Ser Met Ser Glu Gln Thr Gly Leu Leu Lys Ile Lys Thr 
        355                 360                 365             


Glu Pro Leu Asp Phe Asn Asp Tyr Lys Val Leu Met Ala Thr His Gly 
    370                 375                 380                 


Phe Ser Gly Thr Ser Pro Phe Met Asn Gly Gly Leu Gly Ala Thr Ser 
385                 390                 395                 400 


Pro Leu Gly Val His Pro Ser Ala Gln Ser Pro Met Gln His Leu Gly 
                405                 410                 415     


Val Gly Met Glu Ala Pro Leu Leu Gly Phe Pro Thr Met Asn Ser Asn 
            420                 425                 430         


Leu Ser Glu Val Gln Lys Val Leu Gln Ile Val Asp Asn Thr Val Ser 
        435                 440                 445             


Arg Gln Lys Met Asp Cys Lys Ala Glu Glu Ile Ser Lys Leu Lys Gly 
    450                 455                 460                 


Tyr His Met Lys Asp Pro Cys Ser Gln Pro Glu Glu Gln Gly Val Thr 
465                 470                 475                 480 


Ser Pro Asn Ile Pro Pro Val Gly Leu Pro Val Val Ser His Asn Gly 
                485                 490                 495     


Ala Thr Lys Ser Ile Ile Asp Tyr Thr Leu Glu Lys Val Asn Glu Ala 
            500                 505                 510         


Lys Ala Cys Leu Gln Ser Leu Thr Thr Asp Ser Arg Arg Gln Ile Ser 
        515                 520                 525             


Asn Ile Lys Lys Glu Lys Leu Arg Thr Leu Ile Asp Leu Val Thr Asp 
    530                 535                 540                 


Asp Lys Met Ile Glu Asn His Asn Ile Ser Thr Pro Phe Ser Cys Gln 
545                 550                 555                 560 


Phe Cys Lys Glu Ser Phe Pro Gly Pro Ile Pro Leu His Gln His Glu 
                565                 570                 575     


Arg Tyr Leu Cys Lys Met Asn Glu Glu Ile Lys Ala Val Leu Gln Pro 
            580                 585                 590         


His Glu Asn Ile Val Pro Asn Lys Ala Gly Val Phe Val Asp Asn Lys 
        595                 600                 605             


Ala Leu Leu Leu Ser Ser Val Leu Ser Glu Lys Gly Met Thr Ser Pro 
    610                 615                 620                 


Ile Asn Pro Tyr Lys Asp His Met Ser Val Leu Lys Ala Tyr Tyr Ala 
625                 630                 635                 640 


Met Asn Met Glu Pro Asn Ser Asp Glu Leu Leu Lys Ile Ser Ile Ala 
                645                 650                 655     


Val Gly Leu Pro Gln Glu Phe Val Lys Glu Trp Phe Glu Gln Arg Lys 
            660                 665                 670         


Val Tyr Gln Tyr Ser Asn Ser Arg Ser Pro Ser Leu Glu Arg Ser Ser 
        675                 680                 685             


Lys Pro Leu Ala Pro Asn Ser Asn Pro Pro Thr Lys Asp Ser Leu Leu 
    690                 695                 700                 


Pro Arg Ser Pro Val Lys Pro Met Asp Ser Ile Thr Ser Pro Ser Ile 
705                 710                 715                 720 


Ala Glu Leu His Asn Ser Val Thr Asn Cys Asp Pro Pro Leu Arg Leu 
                725                 730                 735     


Thr Lys Pro Ser His Phe Thr Asn Ile Lys Pro Val Glu Lys Leu Asp 
            740                 745                 750         


His Ser Arg Ser Asn Thr Pro Ser Pro Leu Asn Leu Ser Ser Thr Ser 
        755                 760                 765             


Ser Lys Asn Ser His Ser Ser Ser Tyr Thr Pro Asn Ser Phe Ser Ser 
    770                 775                 780                 


Glu Glu Leu Gln Ala Glu Pro Leu Asp Leu Ser Leu Pro Lys Gln Met 
785                 790                 795                 800 


Lys Glu Pro Lys Ser Ile Ile Ala Thr Lys Asn Lys Thr Lys Ala Ser 
                805                 810                 815     


Ser Ile Ser Leu Asp His Asn Ser Val Ser Ser Ser Ser Glu Asn Ser 
            820                 825                 830         


Asp Glu Pro Leu Asn Leu Thr Phe Ile Lys Lys Glu Phe Ser Asn Ser 
        835                 840                 845             


Asn Asn Leu Asp Asn Lys Ser Thr Asn Pro Val Phe Ser Met Asn Pro 
    850                 855                 860                 


Phe Ser Ala Lys Pro Leu Tyr Thr Ala Leu Pro Pro Gln Ser Ala Phe 
865                 870                 875                 880 


Pro Pro Ala Thr Phe Met Pro Pro Val Gln Thr Ser Ile Pro Gly Leu 
                885                 890                 895     


Arg Pro Tyr Pro Gly Leu Asp Gln Met Ser Phe Leu Pro His Met Ala 
            900                 905                 910         


Tyr Thr Tyr Pro Thr Gly Ala Ala Thr Phe Ala Asp Met Gln Gln Arg 
        915                 920                 925             


Arg Lys Tyr Gln Arg Lys Gln Gly Phe Gln Gly Glu Leu Leu Asp Gly 
    930                 935                 940                 


Ala Gln Asp Tyr Met Ser Gly Leu Asp Asp Met Thr Asp Ser Asp Ser 
945                 950                 955                 960 


Cys Leu Ser Arg Lys Lys Ile Lys Lys Thr Glu Ser Gly Met Tyr Ala 
                965                 970                 975     


Cys Asp Leu Cys Asp Lys Thr Phe Gln Lys Ser Ser Ser Leu Leu Arg 
            980                 985                 990         


His Lys Tyr Glu His Thr Gly Lys  Arg Pro His Gln Cys  Gln Ile Cys 
        995                 1000                 1005             


Lys Lys  Ala Phe Lys His Lys  His His Leu Ile Glu  His Ser Arg 
    1010                 1015                 1020             


Leu His  Ser Gly Glu Lys Pro  Tyr Gln Cys Asp Lys  Cys Gly Lys 
    1025                 1030                 1035             


Arg Phe  Ser His Ser Gly Ser  Tyr Ser Gln His Met  Asn His Arg 
    1040                 1045                 1050             


Tyr Ser  Tyr Cys Lys Arg Glu  Ala Glu Glu Arg Glu  Ala Ala Glu 
    1055                 1060                 1065             


Arg Glu  Ala Arg Glu Lys Gly  His Leu Glu Pro Thr  Glu Leu Leu 
    1070                 1075                 1080             


Met Asn  Arg Ala Tyr Leu Gln  Ser Ile Thr Pro Gln  Gly Tyr Ser 
    1085                 1090                 1095             


Asp Ser  Glu Glu Arg Glu Ser  Met Pro Arg Asp Gly  Glu Ser Glu 
    1100                 1105                 1110             


Lys Glu  His Glu Lys Glu Gly  Glu Asp Gly Tyr Gly  Lys Leu Gly 
    1115                 1120                 1125             


Arg Gln  Asp Gly Asp Glu Glu  Phe Glu Glu Glu Glu  Glu Glu Ser 
    1130                 1135                 1140             


Glu Asn  Lys Ser Met Asp Thr  Asp Pro Glu Thr Ile  Arg Asp Glu 
    1145                 1150                 1155             


Glu Glu  Thr Gly Asp His Ser  Met Asp Asp Ser Ser  Glu Asp Gly 
    1160                 1165                 1170             


Lys Met  Glu Thr Lys Ser Asp  His Glu Glu Asp Asn  Met Glu Asp 
    1175                 1180                 1185             


Gly Met  
    1190 


<210>  2802
<211>  994
<212>  PRT
<213>  homo sapiens

<400>  2802

Met Ser Tyr Asp Tyr His Gln Asn Trp Gly Arg Asp Gly Gly Pro Arg 
1               5                   10                  15      


Ser Ser Gly Gly Gly Tyr Gly Gly Gly Pro Ala Gly Gly His Gly Gly 
            20                  25                  30          


Asn Arg Gly Ser Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Arg Gly 
        35                  40                  45              


Gly Arg Gly Arg His Pro Gly His Leu Lys Gly Arg Glu Ile Gly Met 
    50                  55                  60                  


Trp Tyr Ala Lys Lys Gln Gly Gln Lys Asn Lys Glu Ala Glu Arg Gln 
65                  70                  75                  80  


Glu Arg Ala Val Val His Met Asp Glu Arg Arg Glu Glu Gln Ile Val 
                85                  90                  95      


Gln Leu Leu Asn Ser Val Gln Ala Lys Asn Asp Lys Glu Ser Glu Ala 
            100                 105                 110         


Gln Ile Ser Trp Phe Ala Pro Glu Asp His Gly Tyr Gly Thr Glu Val 
        115                 120                 125             


Ser Thr Lys Asn Thr Pro Cys Ser Glu Asn Lys Leu Asp Ile Gln Glu 
    130                 135                 140                 


Lys Lys Leu Ile Asn Gln Glu Lys Lys Met Phe Arg Ile Arg Asn Arg 
145                 150                 155                 160 


Ser Tyr Ile Asp Arg Asp Ser Glu Tyr Leu Leu Gln Glu Asn Glu Pro 
                165                 170                 175     


Asp Gly Thr Leu Asp Gln Lys Leu Leu Glu Asp Leu Gln Lys Lys Lys 
            180                 185                 190         


Asn Asp Leu Arg Tyr Ile Glu Met Gln His Phe Arg Glu Lys Leu Pro 
        195                 200                 205             


Ser Tyr Gly Met Gln Lys Glu Leu Val Asn Leu Ile Asp Asn His Gln 
    210                 215                 220                 


Val Thr Val Ile Ser Gly Glu Thr Gly Cys Gly Lys Thr Thr Gln Val 
225                 230                 235                 240 


Thr Gln Phe Ile Leu Asp Asn Tyr Ile Glu Arg Gly Lys Gly Ser Ala 
                245                 250                 255     


Cys Arg Ile Val Cys Thr Gln Pro Arg Arg Ile Ser Ala Ile Ser Val 
            260                 265                 270         


Ala Glu Arg Val Ala Ala Glu Arg Ala Glu Ser Cys Gly Ser Gly Asn 
        275                 280                 285             


Ser Thr Gly Tyr Gln Ile Arg Leu Gln Ser Arg Leu Pro Arg Lys Gln 
    290                 295                 300                 


Gly Ser Ile Leu Tyr Cys Thr Thr Gly Ile Ile Leu Gln Trp Leu Gln 
305                 310                 315                 320 


Ser Asp Pro Tyr Leu Ser Ser Val Ser His Ile Val Leu Asp Glu Ile 
                325                 330                 335     


His Glu Arg Asn Leu Gln Ser Asp Val Leu Met Thr Val Val Lys Asp 
            340                 345                 350         


Leu Leu Asn Phe Arg Ser Asp Leu Lys Val Ile Leu Met Ser Ala Thr 
        355                 360                 365             


Leu Asn Ala Glu Lys Phe Ser Glu Tyr Phe Gly Asn Cys Pro Met Ile 
    370                 375                 380                 


His Ile Pro Gly Phe Thr Phe Pro Val Val Glu Tyr Leu Leu Glu Asp 
385                 390                 395                 400 


Val Ile Glu Lys Ile Arg Tyr Val Pro Glu Gln Lys Glu His Arg Ser 
                405                 410                 415     


Gln Phe Lys Arg Gly Phe Met Gln Gly His Val Asn Arg Gln Glu Lys 
            420                 425                 430         


Glu Glu Lys Glu Ala Ile Tyr Lys Glu Arg Trp Pro Asp Tyr Val Arg 
        435                 440                 445             


Glu Leu Arg Arg Arg Tyr Ser Ala Ser Thr Val Asp Val Ile Glu Met 
    450                 455                 460                 


Met Glu Asp Asp Lys Val Asp Leu Asn Leu Ile Val Ala Leu Ile Arg 
465                 470                 475                 480 


Tyr Ile Val Leu Glu Glu Glu Asp Gly Ala Ile Leu Val Phe Leu Pro 
                485                 490                 495     


Gly Trp Asp Asn Ile Ser Thr Leu His Asp Leu Leu Met Ser Gln Val 
            500                 505                 510         


Met Phe Lys Ser Val Asn Gln Thr Gln Val Phe Lys Arg Thr Pro Pro 
        515                 520                 525             


Gly Val Arg Lys Ile Val Ile Ala Thr Asn Ile Ala Glu Thr Ser Ile 
    530                 535                 540                 


Thr Ile Asp Asp Val Val Tyr Val Ile Asp Gly Gly Lys Ile Lys Glu 
545                 550                 555                 560 


Thr His Phe Asp Thr Gln Asn Asn Ile Ser Thr Met Ser Ala Glu Trp 
                565                 570                 575     


Val Ser Lys Ala Asn Ala Lys Gln Arg Lys Gly Arg Ala Gly Arg Val 
            580                 585                 590         


Gln Pro Gly His Cys Tyr His Leu Tyr Asn Gly Leu Arg Ala Ser Leu 
        595                 600                 605             


Leu Asp Asp Tyr Gln Leu Pro Glu Ile Leu Arg Thr Pro Leu Glu Glu 
    610                 615                 620                 


Leu Cys Leu Gln Ile Lys Ile Leu Arg Leu Gly Gly Ile Ala Tyr Phe 
625                 630                 635                 640 


Leu Ser Arg Leu Met Asp Pro Pro Ser Asn Glu Ala Val Leu Leu Ser 
                645                 650                 655     


Ile Arg His Leu Met Glu Leu Asn Ala Leu Asp Lys Gln Glu Glu Leu 
            660                 665                 670         


Thr Pro Leu Gly Val His Leu Ala Arg Leu Pro Val Glu Pro His Ile 
        675                 680                 685             


Gly Lys Met Ile Leu Phe Gly Ala Leu Phe Cys Cys Leu Asp Pro Val 
    690                 695                 700                 


Leu Thr Ile Ala Ala Ser Leu Ser Phe Lys Asp Pro Phe Val Ile Pro 
705                 710                 715                 720 


Leu Gly Lys Glu Lys Ile Ala Asp Ala Arg Arg Lys Glu Leu Ala Lys 
                725                 730                 735     


Asp Thr Arg Ser Asp His Leu Thr Val Val Asn Ala Phe Glu Gly Trp 
            740                 745                 750         


Glu Glu Ala Arg Arg Arg Gly Phe Arg Tyr Glu Lys Asp Tyr Cys Trp 
        755                 760                 765             


Glu Tyr Phe Leu Ser Ser Asn Thr Leu Gln Met Leu His Asn Met Lys 
    770                 775                 780                 


Gly Gln Phe Ala Glu His Leu Leu Gly Ala Gly Phe Val Ser Ser Arg 
785                 790                 795                 800 


Asn Pro Lys Asp Pro Glu Ser Asn Ile Asn Ser Asp Asn Glu Lys Ile 
                805                 810                 815     


Ile Lys Ala Val Ile Cys Ala Gly Leu Tyr Pro Lys Val Ala Lys Ile 
            820                 825                 830         


Arg Leu Asn Leu Gly Lys Lys Arg Lys Met Val Lys Val Tyr Thr Lys 
        835                 840                 845             


Thr Asp Gly Leu Val Ala Val His Pro Lys Ser Val Asn Val Glu Gln 
    850                 855                 860                 


Thr Asp Phe His Tyr Asn Trp Leu Ile Tyr His Leu Lys Met Arg Thr 
865                 870                 875                 880 


Ser Ser Ile Tyr Leu Tyr Asp Cys Thr Glu Val Ser Pro Tyr Cys Leu 
                885                 890                 895     


Leu Phe Phe Gly Gly Asp Ile Ser Ile Gln Lys Asp Asn Asp Gln Glu 
            900                 905                 910         


Thr Ile Ala Val Asp Glu Trp Ile Val Phe Gln Ser Pro Ala Arg Ile 
        915                 920                 925             


Ala His Leu Val Lys Glu Leu Arg Lys Glu Leu Asp Ile Leu Leu Gln 
    930                 935                 940                 


Glu Lys Ile Glu Ser Pro His Pro Val Asp Trp Asn Asp Thr Lys Ser 
945                 950                 955                 960 


Arg Asp Cys Ala Val Leu Ser Ala Ile Ile Asp Leu Ile Lys Thr Gln 
                965                 970                 975     


Glu Lys Ala Thr Pro Arg Asn Phe Pro Pro Arg Phe Gln Asp Gly Tyr 
            980                 985                 990         


Tyr Ser 
        


<210>  2803
<211>  1147
<212>  PRT
<213>  homo sapiens

<400>  2803

Met Asp Glu Pro Pro Phe Ser Glu Ala Ala Leu Glu Gln Ala Leu Gly 
1               5                   10                  15      


Glu Pro Cys Asp Leu Asp Ala Ala Leu Leu Thr Asp Ile Glu Asp Met 
            20                  25                  30          


Leu Gln Leu Ile Asn Asn Gln Asp Ser Asp Phe Pro Gly Leu Phe Asp 
        35                  40                  45              


Pro Pro Tyr Ala Gly Ser Gly Ala Gly Gly Thr Asp Pro Ala Ser Pro 
    50                  55                  60                  


Asp Thr Ser Ser Pro Gly Ser Leu Ser Pro Pro Pro Ala Thr Leu Ser 
65                  70                  75                  80  


Ser Ser Leu Glu Ala Phe Leu Ser Gly Pro Gln Ala Ala Pro Ser Pro 
                85                  90                  95      


Leu Ser Pro Pro Gln Pro Ala Pro Thr Pro Leu Lys Met Tyr Pro Ser 
            100                 105                 110         


Met Pro Ala Phe Ser Pro Gly Pro Gly Ile Lys Glu Glu Ser Val Pro 
        115                 120                 125             


Leu Ser Ile Leu Gln Thr Pro Thr Pro Gln Pro Leu Pro Gly Ala Leu 
    130                 135                 140                 


Leu Pro Gln Ser Phe Pro Ala Pro Ala Pro Pro Gln Phe Ser Ser Thr 
145                 150                 155                 160 


Pro Val Leu Gly Tyr Pro Ser Pro Pro Gly Gly Phe Ser Thr Gly Ser 
                165                 170                 175     


Pro Pro Gly Asn Thr Gln Gln Pro Leu Pro Gly Leu Pro Leu Ala Ser 
            180                 185                 190         


Pro Pro Gly Val Pro Pro Val Ser Leu His Thr Gln Val Gln Ser Val 
        195                 200                 205             


Val Pro Gln Gln Leu Leu Thr Val Thr Ala Ala Pro Thr Ala Ala Pro 
    210                 215                 220                 


Val Thr Thr Thr Val Thr Ser Gln Ile Gln Gln Val Pro Val Leu Leu 
225                 230                 235                 240 


Gln Pro His Phe Ile Lys Ala Asp Ser Leu Leu Leu Thr Ala Met Lys 
                245                 250                 255     


Thr Asp Gly Ala Thr Val Lys Ala Ala Gly Leu Ser Pro Leu Val Ser 
            260                 265                 270         


Gly Thr Thr Val Gln Thr Gly Pro Leu Pro Thr Leu Val Ser Gly Gly 
        275                 280                 285             


Thr Ile Leu Ala Thr Val Pro Leu Val Val Asp Ala Glu Lys Leu Pro 
    290                 295                 300                 


Ile Asn Arg Leu Ala Ala Gly Ser Lys Ala Pro Ala Ser Ala Gln Ser 
305                 310                 315                 320 


Arg Gly Glu Lys Arg Thr Ala His Asn Ala Ile Glu Lys Arg Tyr Arg 
                325                 330                 335     


Ser Ser Ile Asn Asp Lys Ile Ile Glu Leu Lys Asp Leu Val Val Gly 
            340                 345                 350         


Thr Glu Ala Lys Leu Asn Lys Ser Ala Val Leu Arg Lys Ala Ile Asp 
        355                 360                 365             


Tyr Ile Arg Phe Leu Gln His Ser Asn Gln Lys Leu Lys Gln Glu Asn 
    370                 375                 380                 


Leu Ser Leu Arg Thr Ala Val His Lys Ser Lys Ser Leu Lys Asp Leu 
385                 390                 395                 400 


Val Ser Ala Cys Gly Ser Gly Gly Asn Thr Asp Val Leu Met Glu Gly 
                405                 410                 415     


Val Lys Thr Glu Val Glu Asp Thr Leu Thr Pro Pro Pro Ser Asp Ala 
            420                 425                 430         


Gly Ser Pro Phe Gln Ser Ser Pro Leu Ser Leu Gly Ser Arg Gly Ser 
        435                 440                 445             


Gly Ser Gly Gly Ser Gly Ser Asp Ser Glu Pro Asp Ser Pro Val Phe 
    450                 455                 460                 


Glu Asp Ser Lys Ala Lys Pro Glu Gln Arg Pro Ser Leu His Ser Arg 
465                 470                 475                 480 


Gly Met Leu Asp Arg Ser Arg Leu Ala Leu Cys Thr Leu Val Phe Leu 
                485                 490                 495     


Cys Leu Ser Cys Asn Pro Leu Ala Ser Leu Leu Gly Ala Arg Gly Leu 
            500                 505                 510         


Pro Ser Pro Ser Asp Thr Thr Ser Val Tyr His Ser Pro Gly Arg Asn 
        515                 520                 525             


Val Leu Gly Thr Glu Ser Arg Asp Gly Pro Gly Trp Ala Gln Trp Leu 
    530                 535                 540                 


Leu Pro Pro Val Val Trp Leu Leu Asn Gly Leu Leu Val Leu Val Ser 
545                 550                 555                 560 


Leu Val Leu Leu Phe Val Tyr Gly Glu Pro Val Thr Arg Pro His Ser 
                565                 570                 575     


Gly Pro Ala Val Tyr Phe Trp Arg His Arg Lys Gln Ala Asp Leu Asp 
            580                 585                 590         


Leu Ala Arg Gly Asp Phe Ala Gln Ala Ala Gln Gln Leu Trp Leu Ala 
        595                 600                 605             


Leu Arg Ala Leu Gly Arg Pro Leu Pro Thr Ser His Leu Asp Leu Ala 
    610                 615                 620                 


Cys Ser Leu Leu Trp Asn Leu Ile Arg His Leu Leu Gln Arg Leu Trp 
625                 630                 635                 640 


Val Gly Arg Trp Leu Ala Gly Arg Ala Gly Gly Leu Gln Gln Asp Cys 
                645                 650                 655     


Ala Leu Arg Val Asp Ala Ser Ala Ser Ala Arg Asp Ala Ala Leu Val 
            660                 665                 670         


Tyr His Lys Leu His Gln Leu His Thr Met Gly Lys His Thr Gly Gly 
        675                 680                 685             


His Leu Thr Ala Thr Asn Leu Ala Leu Ser Ala Leu Asn Leu Ala Glu 
    690                 695                 700                 


Cys Ala Gly Asp Ala Val Ser Val Ala Thr Leu Ala Glu Ile Tyr Val 
705                 710                 715                 720 


Ala Ala Ala Leu Arg Val Lys Thr Ser Leu Pro Arg Ala Leu His Phe 
                725                 730                 735     


Leu Thr Arg Phe Phe Leu Ser Ser Ala Arg Gln Ala Cys Leu Ala Gln 
            740                 745                 750         


Ser Gly Ser Val Pro Pro Ala Met Gln Trp Leu Cys His Pro Val Gly 
        755                 760                 765             


His Arg Phe Phe Val Asp Gly Asp Trp Ser Val Leu Ser Thr Pro Trp 
    770                 775                 780                 


Glu Ser Leu Tyr Ser Leu Ala Gly Asn Pro Val Asp Pro Leu Ala Gln 
785                 790                 795                 800 


Val Thr Gln Leu Phe Arg Glu His Leu Leu Glu Arg Ala Leu Asn Cys 
                805                 810                 815     


Val Thr Gln Pro Asn Pro Ser Pro Gly Ser Ala Asp Gly Asp Lys Glu 
            820                 825                 830         


Phe Ser Asp Ala Leu Gly Tyr Leu Gln Leu Leu Asn Ser Cys Ser Asp 
        835                 840                 845             


Ala Ala Gly Ala Pro Ala Tyr Ser Phe Ser Ile Ser Ser Ser Met Ala 
    850                 855                 860                 


Thr Thr Thr Gly Val Asp Pro Val Ala Lys Trp Trp Ala Ser Leu Thr 
865                 870                 875                 880 


Ala Val Val Ile His Trp Leu Arg Arg Asp Glu Glu Ala Ala Glu Arg 
                885                 890                 895     


Leu Cys Pro Leu Val Glu His Leu Pro Arg Val Leu Gln Glu Ser Glu 
            900                 905                 910         


Arg Pro Leu Pro Arg Ala Ala Leu His Ser Phe Lys Ala Ala Arg Ala 
        915                 920                 925             


Leu Leu Gly Cys Ala Lys Ala Glu Ser Gly Pro Ala Ser Leu Thr Ile 
    930                 935                 940                 


Cys Glu Lys Ala Ser Gly Tyr Leu Gln Asp Ser Leu Ala Thr Thr Pro 
945                 950                 955                 960 


Ala Ser Ser Ser Ile Asp Lys Ala Val Gln Leu Phe Leu Cys Asp Leu 
                965                 970                 975     


Leu Leu Val Val Arg Thr Ser Leu Trp Arg Gln Gln Gln Pro Pro Ala 
            980                 985                 990         


Pro Ala Pro Ala Ala Gln Gly Thr  Ser Ser Arg Pro Gln  Ala Ser Ala 
        995                 1000                 1005             


Leu Glu  Leu Arg Gly Phe Gln  Arg Asp Leu Ser Ser  Leu Arg Arg 
    1010                 1015                 1020             


Leu Ala  Gln Ser Phe Arg Pro  Ala Met Arg Arg Val  Phe Leu His 
    1025                 1030                 1035             


Glu Ala  Thr Ala Arg Leu Met  Ala Gly Ala Ser Pro  Thr Arg Thr 
    1040                 1045                 1050             


His Gln  Leu Leu Asp Arg Ser  Leu Arg Arg Arg Ala  Gly Pro Gly 
    1055                 1060                 1065             


Gly Lys  Gly Gly Ala Val Ala  Glu Leu Glu Pro Arg  Pro Thr Arg 
    1070                 1075                 1080             


Arg Glu  His Ala Glu Ala Leu  Leu Leu Ala Ser Cys  Tyr Leu Pro 
    1085                 1090                 1095             


Pro Gly  Phe Leu Ser Ala Pro  Gly Gln Arg Val Gly  Met Leu Ala 
    1100                 1105                 1110             


Glu Ala  Ala Arg Thr Leu Glu  Lys Leu Gly Asp Arg  Arg Leu Leu 
    1115                 1120                 1125             


His Asp  Cys Gln Gln Met Leu  Met Arg Leu Gly Gly  Gly Thr Thr 
    1130                 1135                 1140             


Val Thr  Ser Ser 
    1145         


<210>  2804
<211>  353
<212>  PRT
<213>  homo sapiens

<400>  2804

Met Ala Met Thr Leu Leu Glu Asp Trp Cys Arg Gly Met Asp Val Asn 
1               5                   10                  15      


Ser Gln Arg Ala Leu Leu Val Trp Gly Ile Pro Val Asn Cys Asp Glu 
            20                  25                  30          


Ala Glu Ile Glu Glu Thr Leu Gln Ala Ala Met Pro Gln Val Ser Tyr 
        35                  40                  45              


Arg Met Leu Gly Arg Met Phe Trp Arg Glu Glu Asn Ala Lys Ala Ala 
    50                  55                  60                  


Leu Leu Glu Leu Thr Gly Ala Val Asp Tyr Ala Ala Ile Pro Arg Glu 
65                  70                  75                  80  


Met Pro Gly Lys Gly Gly Val Trp Lys Val Leu Phe Lys Pro Pro Thr 
                85                  90                  95      


Ser Asp Ala Glu Phe Leu Glu Arg Leu His Leu Phe Leu Ala Arg Glu 
            100                 105                 110         


Gly Trp Thr Val Gln Asp Val Ala Arg Val Leu Gly Phe Gln Asn Pro 
        115                 120                 125             


Thr Pro Thr Pro Gly Pro Glu Met Pro Ala Glu Met Leu Asn Tyr Ile 
    130                 135                 140                 


Leu Asp Asn Val Ile Gln Pro Leu Val Glu Ser Ile Trp Tyr Lys Arg 
145                 150                 155                 160 


Leu Thr Leu Phe Ser Gly Arg Asp Ile Pro Gly Pro Gly Glu Glu Thr 
                165                 170                 175     


Phe Asp Pro Trp Leu Glu His Thr Asn Glu Val Leu Glu Glu Trp Gln 
            180                 185                 190         


Val Ser Asp Val Glu Lys Arg Arg Arg Leu Met Glu Ser Leu Arg Gly 
        195                 200                 205             


Pro Ala Ala Asp Val Ile Arg Ile Leu Lys Ser Asn Asn Pro Ala Ile 
    210                 215                 220                 


Thr Thr Ala Glu Cys Leu Lys Ala Leu Glu Gln Val Phe Gly Ser Val 
225                 230                 235                 240 


Glu Ser Ser Arg Asp Ala Gln Ile Lys Phe Leu Asn Thr Tyr Gln Asn 
                245                 250                 255     


Pro Gly Glu Lys Leu Ser Ala Tyr Val Ile Arg Leu Glu Pro Leu Leu 
            260                 265                 270         


Gln Lys Val Val Glu Lys Gly Ala Ile Asp Lys Asp Asn Val Asn Gln 
        275                 280                 285             


Ala Arg Leu Glu Gln Val Ile Ala Gly Ala Asn His Ser Gly Ala Ile 
    290                 295                 300                 


Arg Arg Gln Leu Trp Leu Thr Gly Ala Gly Glu Gly Pro Ala Pro Asn 
305                 310                 315                 320 


Leu Phe Gln Leu Leu Val Gln Ile Arg Glu Glu Glu Ala Lys Glu Glu 
                325                 330                 335     


Glu Glu Glu Ala Glu Ala Thr Leu Leu Gln Leu Gly Leu Glu Gly His 
            340                 345                 350         


Phe 
    


<210>  2805
<211>  847
<212>  PRT
<213>  homo sapiens

<400>  2805

Met Glu Ala Ala Arg Pro Ser Gly Ser Trp Asn Gly Ala Leu Cys Arg 
1               5                   10                  15      


Leu Leu Leu Leu Thr Leu Ala Ile Leu Ile Phe Ala Ser Asp Ala Cys 
            20                  25                  30          


Lys Asn Val Thr Leu His Val Pro Ser Lys Leu Asp Ala Glu Lys Leu 
        35                  40                  45              


Val Gly Arg Val Asn Leu Lys Glu Cys Phe Thr Ala Ala Asn Leu Ile 
    50                  55                  60                  


His Ser Ser Asp Pro Asp Phe Gln Ile Leu Glu Asp Gly Ser Val Tyr 
65                  70                  75                  80  


Thr Thr Asn Thr Ile Leu Leu Ser Ser Glu Lys Arg Ser Phe Thr Ile 
                85                  90                  95      


Leu Leu Ser Asn Thr Glu Asn Gln Glu Lys Lys Lys Ile Phe Val Phe 
            100                 105                 110         


Leu Glu His Gln Thr Lys Val Leu Lys Lys Arg His Thr Lys Glu Lys 
        115                 120                 125             


Val Leu Arg Arg Ala Lys Arg Arg Trp Ala Pro Ile Pro Cys Ser Met 
    130                 135                 140                 


Leu Glu Asn Ser Leu Gly Pro Phe Pro Leu Phe Leu Gln Gln Val Gln 
145                 150                 155                 160 


Ser Asp Thr Ala Gln Asn Tyr Thr Ile Tyr Tyr Ser Ile Arg Gly Pro 
                165                 170                 175     


Gly Val Asp Gln Glu Pro Arg Asn Leu Phe Tyr Val Glu Arg Asp Thr 
            180                 185                 190         


Gly Asn Leu Tyr Cys Thr Arg Pro Val Asp Arg Glu Gln Tyr Glu Ser 
        195                 200                 205             


Phe Glu Ile Ile Ala Phe Ala Thr Thr Pro Asp Gly Tyr Thr Pro Glu 
    210                 215                 220                 


Leu Pro Leu Pro Leu Ile Ile Lys Ile Glu Asp Glu Asn Asp Asn Tyr 
225                 230                 235                 240 


Pro Ile Phe Thr Glu Glu Thr Tyr Thr Phe Thr Ile Phe Glu Asn Cys 
                245                 250                 255     


Arg Val Gly Thr Thr Val Gly Gln Val Cys Ala Thr Asp Lys Asp Glu 
            260                 265                 270         


Pro Asp Thr Met His Thr Arg Leu Lys Tyr Ser Ile Ile Gly Gln Val 
        275                 280                 285             


Pro Pro Ser Pro Thr Leu Phe Ser Met His Pro Thr Thr Gly Val Ile 
    290                 295                 300                 


Thr Thr Thr Ser Ser Gln Leu Asp Arg Glu Leu Ile Asp Lys Tyr Gln 
305                 310                 315                 320 


Leu Lys Ile Lys Val Gln Asp Met Asp Gly Gln Tyr Phe Gly Leu Gln 
                325                 330                 335     


Thr Thr Ser Thr Cys Ile Ile Asn Ile Asp Asp Val Asn Asp His Leu 
            340                 345                 350         


Pro Thr Phe Thr Arg Thr Ser Tyr Val Thr Ser Val Glu Glu Asn Thr 
        355                 360                 365             


Val Asp Val Glu Ile Leu Arg Val Thr Val Glu Asp Lys Asp Leu Val 
    370                 375                 380                 


Asn Thr Ala Asn Trp Arg Ala Asn Tyr Thr Ile Leu Lys Gly Asn Glu 
385                 390                 395                 400 


Asn Gly Asn Phe Lys Ile Val Thr Asp Ala Lys Thr Asn Glu Gly Val 
                405                 410                 415     


Leu Cys Val Val Lys Pro Leu Asn Tyr Glu Glu Lys Gln Gln Met Ile 
            420                 425                 430         


Leu Gln Ile Gly Val Val Asn Glu Ala Pro Phe Ser Arg Glu Ala Ser 
        435                 440                 445             


Pro Arg Ser Ala Met Ser Thr Ala Thr Val Thr Val Asn Val Glu Asp 
    450                 455                 460                 


Gln Asp Glu Gly Pro Glu Cys Asn Pro Pro Ile Gln Thr Val Arg Met 
465                 470                 475                 480 


Lys Glu Asn Ala Glu Val Gly Thr Thr Ser Asn Gly Tyr Lys Ala Tyr 
                485                 490                 495     


Asp Pro Glu Thr Arg Ser Ser Ser Gly Ile Arg Tyr Lys Lys Leu Thr 
            500                 505                 510         


Asp Pro Thr Gly Trp Val Thr Ile Asp Glu Asn Thr Gly Ser Ile Lys 
        515                 520                 525             


Val Phe Arg Ser Leu Asp Arg Glu Ala Glu Thr Ile Lys Asn Gly Ile 
    530                 535                 540                 


Tyr Asn Ile Thr Val Leu Ala Ser Asp Gln Gly Gly Arg Thr Cys Thr 
545                 550                 555                 560 


Gly Thr Leu Gly Ile Ile Leu Gln Asp Val Asn Asp Asn Ser Pro Phe 
                565                 570                 575     


Ile Pro Lys Lys Thr Val Ile Ile Cys Lys Pro Thr Met Ser Ser Ala 
            580                 585                 590         


Glu Ile Val Ala Val Asp Pro Asp Glu Pro Ile His Gly Pro Pro Phe 
        595                 600                 605             


Asp Phe Ser Leu Glu Ser Ser Thr Ser Glu Val Gln Arg Met Trp Arg 
    610                 615                 620                 


Leu Lys Ala Ile Asn Asp Thr Ala Ala Arg Leu Ser Tyr Gln Asn Asp 
625                 630                 635                 640 


Pro Pro Phe Gly Ser Tyr Val Val Pro Ile Thr Val Arg Asp Arg Leu 
                645                 650                 655     


Gly Met Ser Ser Val Thr Ser Leu Asp Val Thr Leu Cys Asp Cys Ile 
            660                 665                 670         


Thr Glu Asn Asp Cys Thr His Arg Val Asp Pro Arg Ile Gly Gly Gly 
        675                 680                 685             


Gly Val Gln Leu Gly Lys Trp Ala Ile Leu Ala Ile Leu Leu Gly Ile 
    690                 695                 700                 


Ala Leu Leu Phe Cys Ile Leu Phe Thr Leu Val Cys Gly Ala Ser Gly 
705                 710                 715                 720 


Thr Ser Lys Gln Pro Lys Val Ile Pro Asp Asp Leu Ala Gln Gln Asn 
                725                 730                 735     


Leu Ile Val Ser Asn Thr Glu Ala Pro Gly Asp Asp Lys Val Tyr Ser 
            740                 745                 750         


Ala Asn Gly Phe Thr Thr Gln Thr Val Gly Ala Ser Ala Gln Gly Val 
        755                 760                 765             


Cys Gly Thr Val Gly Ser Gly Ile Lys Asn Gly Gly Gln Glu Thr Ile 
    770                 775                 780                 


Glu Met Val Lys Gly Gly His Gln Thr Ser Glu Ser Cys Arg Gly Ala 
785                 790                 795                 800 


Gly His His His Thr Leu Asp Ser Cys Arg Gly Gly His Thr Glu Val 
                805                 810                 815     


Asp Asn Cys Arg Tyr Thr Tyr Ser Glu Trp His Ser Phe Thr Gln Pro 
            820                 825                 830         


Arg Leu Gly Glu Glu Ser Ile Arg Gly His Thr Leu Ile Lys Asn 
        835                 840                 845         


<210>  2806
<211>  343
<212>  PRT
<213>  homo sapiens

<400>  2806

Met Ala Ala Ala Thr Glu Leu Asn Arg Pro Ser Ser Gly Asp Arg Asn 
1               5                   10                  15      


Leu Glu Arg Arg Cys Arg Pro Asn Leu Ser Arg Glu Val Leu Tyr Glu 
            20                  25                  30          


Ile Phe Arg Ser Leu His Thr Leu Val Gly Gln Leu Asp Leu Arg Asp 
        35                  40                  45              


Asp Val Val Lys Ile Thr Ile Asp Trp Asn Lys Leu Gln Ser Leu Ser 
    50                  55                  60                  


Ala Phe Gln Pro Ala Leu Leu Phe Ser Ala Leu Glu Gln His Ile Leu 
65                  70                  75                  80  


Tyr Leu Gln Pro Phe Leu Ala Lys Leu Gln Ser Pro Ile Lys Glu Glu 
                85                  90                  95      


Asn Thr Thr Ala Val Glu Glu Ile Gly Arg Thr Glu Met Gly Asn Lys 
            100                 105                 110         


Asn Glu Val Asn Asp Lys Phe Ser Ile Gly Asp Leu Gln Glu Glu Glu 
        115                 120                 125             


Lys His Lys Glu Ser Asp Leu Arg Asp Val Lys Lys Thr Gln Ile His 
    130                 135                 140                 


Phe Asp Pro Glu Val Val Gln Ile Lys Ala Gly Lys Ala Glu Ile Asp 
145                 150                 155                 160 


Arg Arg Ile Ser Ala Phe Ile Glu Arg Lys Gln Ala Glu Ile Asn Glu 
                165                 170                 175     


Asn Asn Val Arg Glu Phe Cys Asn Val Ile Asp Cys Asn Gln Glu Asn 
            180                 185                 190         


Ser Cys Ala Arg Thr Asp Ala Ile Phe Thr Pro Tyr Pro Gly Phe Lys 
        195                 200                 205             


Ser His Val Lys Val Ser Arg Val Val Asn Thr Tyr Gly Pro Gln Thr 
    210                 215                 220                 


Arg Pro Glu Gly Ile Pro Gly Ser Gly His Lys Pro Asn Ser Met Leu 
225                 230                 235                 240 


Arg Asp Cys Gly Asn Gln Ala Val Glu Glu Arg Leu Gln Asn Ile Glu 
                245                 250                 255     


Ala His Leu Arg Leu Gln Thr Gly Gly Pro Val Pro Arg Asp Ile Tyr 
            260                 265                 270         


Gln Arg Ile Lys Lys Leu Glu Asp Lys Ile Leu Glu Leu Glu Gly Ile 
        275                 280                 285             


Ser Pro Glu Tyr Phe Gln Ser Val Ser Phe Ser Gly Lys Arg Arg Lys 
    290                 295                 300                 


Val Gln Pro Pro Gln Asn Tyr Ser Leu Ala Glu Leu Asp Glu Lys Ile 
305                 310                 315                 320 


Ser Ala Leu Lys Gln Ala Leu Leu Arg Lys Ser Arg Glu Ala Glu Ser 
                325                 330                 335     


Met Ala Thr His His Leu Pro 
            340             


<210>  2807
<211>  553
<212>  PRT
<213>  homo sapiens

<400>  2807

Met Ser Asn Asn Gly Leu Asp Ile Gln Asp Lys Pro Pro Ala Pro Pro 
1               5                   10                  15      


Met Arg Asn Thr Ser Thr Met Ile Gly Ala Gly Ser Lys Asp Ala Gly 
            20                  25                  30          


Thr Leu Asn His Gly Ser Lys Pro Leu Pro Pro Asn Pro Glu Glu Lys 
        35                  40                  45              


Lys Lys Lys Asp Arg Phe Tyr Arg Ser Ile Leu Pro Gly Asp Lys Thr 
    50                  55                  60                  


Asn Lys Lys Lys Glu Lys Glu Arg Pro Glu Ile Ser Leu Pro Ser Asp 
65                  70                  75                  80  


Phe Glu His Thr Ile His Val Gly Phe Asp Ala Val Thr Gly Glu Phe 
                85                  90                  95      


Thr Gly Met Pro Glu Gln Trp Ala Arg Leu Leu Gln Thr Ser Asn Ile 
            100                 105                 110         


Thr Lys Ser Glu Gln Lys Lys Asn Pro Gln Ala Val Leu Asp Val Leu 
        115                 120                 125             


Glu Phe Tyr Asn Ser Lys Lys Thr Ser Asn Ser Gln Lys Tyr Met Ser 
    130                 135                 140                 


Phe Thr Asp Lys Ser Ala Glu Asp Tyr Asn Ser Ser Asn Ala Leu Asn 
145                 150                 155                 160 


Val Lys Ala Val Ser Glu Thr Pro Ala Val Pro Pro Val Ser Glu Asp 
                165                 170                 175     


Glu Asp Asp Asp Asp Asp Asp Ala Thr Pro Pro Pro Val Ile Ala Pro 
            180                 185                 190         


Arg Pro Glu His Thr Lys Ser Val Tyr Thr Arg Ser Val Ile Glu Pro 
        195                 200                 205             


Leu Pro Val Thr Pro Thr Arg Asp Val Ala Thr Ser Pro Ile Ser Pro 
    210                 215                 220                 


Thr Glu Asn Asn Thr Thr Pro Pro Asp Ala Leu Thr Arg Asn Thr Glu 
225                 230                 235                 240 


Lys Gln Lys Lys Lys Pro Lys Met Ser Asp Glu Glu Ile Leu Glu Lys 
                245                 250                 255     


Leu Arg Ser Ile Val Ser Val Gly Asp Pro Lys Lys Lys Tyr Thr Arg 
            260                 265                 270         


Phe Glu Lys Ile Gly Gln Gly Ala Ser Gly Thr Val Tyr Thr Ala Met 
        275                 280                 285             


Asp Val Ala Thr Gly Gln Glu Val Ala Ile Lys Gln Met Asn Leu Gln 
    290                 295                 300                 


Gln Gln Pro Lys Lys Glu Leu Ile Ile Asn Glu Ile Leu Val Met Arg 
305                 310                 315                 320 


Glu Asn Lys Asn Pro Asn Ile Val Asn Tyr Leu Asp Ser Tyr Leu Val 
                325                 330                 335     


Gly Asp Glu Leu Trp Val Val Met Glu Tyr Leu Ala Gly Gly Ser Leu 
            340                 345                 350         


Thr Asp Val Val Thr Glu Thr Cys Met Asp Glu Gly Gln Ile Ala Ala 
        355                 360                 365             


Val Cys Arg Glu Cys Leu Gln Ala Leu Glu Phe Leu His Ser Asn Gln 
    370                 375                 380                 


Val Ile His Arg Asp Ile Lys Ser Asp Asn Ile Leu Leu Gly Met Asp 
385                 390                 395                 400 


Gly Ser Val Lys Leu Thr Asp Phe Gly Phe Cys Ala Gln Ile Thr Pro 
                405                 410                 415     


Glu Gln Ser Lys Arg Ser Thr Met Val Gly Thr Pro Tyr Trp Met Ala 
            420                 425                 430         


Pro Glu Val Val Thr Arg Lys Ala Tyr Gly Pro Lys Val Asp Ile Trp 
        435                 440                 445             


Ser Leu Gly Ile Met Ala Ile Glu Met Ile Glu Gly Glu Pro Pro Tyr 
    450                 455                 460                 


Leu Asn Glu Asn Pro Leu Arg Ala Leu Tyr Leu Ile Ala Thr Asn Gly 
465                 470                 475                 480 


Thr Pro Glu Leu Gln Asn Pro Glu Lys Leu Ser Ala Ile Phe Arg Asp 
                485                 490                 495     


Phe Leu Asn Arg Cys Leu Glu Met Asp Val Glu Lys Arg Gly Ser Ala 
            500                 505                 510         


Lys Glu Leu Leu Gln Val Arg Lys Leu Arg Phe Gln Val Phe Ser Asn 
        515                 520                 525             


Phe Ser Met Ile Ala Ala Ser Ile Pro Glu Asp Cys Gln Ala Pro Leu 
    530                 535                 540                 


Gln Pro His Ser Thr Asp Cys Cys Ser 
545                 550             


<210>  2808
<211>  866
<212>  PRT
<213>  homo sapiens

<400>  2808

Met Gly Phe Pro Pro Leu Leu Lys Gly Gln Ala Ser Ala Thr Arg Ser 
1               5                   10                  15      


Ser Leu Ala Ser Cys Ser Trp Val Val Phe Phe Leu Ser Cys Leu Ser 
            20                  25                  30          


Arg His Ala Pro Glu Ile Glu Gly Gly Arg Arg Trp Thr Glu Leu Ile 
        35                  40                  45              


Arg Thr Met Glu Ser Arg Val Leu Leu Arg Thr Phe Cys Leu Ile Phe 
    50                  55                  60                  


Gly Leu Gly Ala Val Trp Gly Leu Gly Val Asp Pro Ser Leu Gln Ile 
65                  70                  75                  80  


Asp Val Leu Thr Glu Leu Glu Leu Gly Glu Ser Thr Thr Gly Val Arg 
                85                  90                  95      


Gln Val Pro Gly Leu His Asn Gly Thr Lys Ala Phe Leu Phe Gln Asp 
            100                 105                 110         


Thr Pro Arg Ser Ile Lys Ala Ser Thr Ala Thr Ala Glu Gln Phe Phe 
        115                 120                 125             


Gln Lys Leu Arg Asn Lys His Glu Phe Thr Ile Leu Val Thr Leu Lys 
    130                 135                 140                 


Gln Thr His Leu Asn Ser Gly Val Ile Leu Ser Ile His His Leu Asp 
145                 150                 155                 160 


His Arg Tyr Leu Glu Leu Glu Ser Ser Gly His Arg Asn Glu Val Arg 
                165                 170                 175     


Leu His Tyr Arg Ser Gly Ser His Arg Pro His Thr Glu Val Phe Pro 
            180                 185                 190         


Tyr Ile Leu Ala Asp Asp Lys Trp His Lys Leu Ser Leu Ala Ile Ser 
        195                 200                 205             


Ala Ser His Leu Ile Leu His Ile Asp Cys Asn Lys Ile Tyr Glu Arg 
    210                 215                 220                 


Val Val Glu Lys Pro Ser Thr Asp Leu Pro Leu Gly Thr Thr Phe Trp 
225                 230                 235                 240 


Leu Gly Gln Arg Asn Asn Ala His Gly Tyr Phe Lys Gly Ile Met Gln 
                245                 250                 255     


Asp Val Gln Leu Leu Val Met Pro Gln Gly Phe Ile Ala Gln Cys Pro 
            260                 265                 270         


Asp Leu Asn Arg Thr Cys Pro Thr Cys Asn Asp Phe His Gly Leu Val 
        275                 280                 285             


Gln Lys Ile Met Glu Leu Gln Asp Ile Leu Ala Lys Thr Ser Ala Lys 
    290                 295                 300                 


Leu Ser Arg Ala Glu Gln Arg Met Asn Arg Leu Asp Gln Cys Tyr Cys 
305                 310                 315                 320 


Glu Arg Thr Cys Thr Met Lys Gly Thr Thr Tyr Arg Glu Phe Glu Ser 
                325                 330                 335     


Trp Ile Asp Gly Cys Lys Asn Cys Thr Cys Leu Asn Gly Thr Ile Gln 
            340                 345                 350         


Cys Glu Thr Leu Ile Cys Pro Asn Pro Asp Cys Pro Leu Lys Ser Ala 
        355                 360                 365             


Leu Ala Tyr Val Asp Gly Lys Cys Cys Lys Glu Cys Lys Ser Ile Cys 
    370                 375                 380                 


Gln Phe Gln Gly Arg Thr Tyr Phe Glu Gly Glu Arg Asn Thr Val Tyr 
385                 390                 395                 400 


Ser Ser Ser Gly Val Cys Val Leu Tyr Glu Cys Lys Asp Gln Thr Met 
                405                 410                 415     


Lys Leu Val Glu Ser Ser Gly Cys Pro Ala Leu Asp Cys Pro Glu Ser 
            420                 425                 430         


His Gln Ile Thr Leu Ser His Ser Cys Cys Lys Val Cys Lys Gly Tyr 
        435                 440                 445             


Asp Phe Cys Ser Glu Arg His Asn Cys Met Glu Asn Ser Ile Cys Arg 
    450                 455                 460                 


Asn Leu Asn Asp Arg Ala Val Cys Ser Cys Arg Asp Gly Phe Arg Ala 
465                 470                 475                 480 


Leu Arg Glu Asp Asn Ala Tyr Cys Glu Asp Ile Asp Glu Cys Ala Glu 
                485                 490                 495     


Gly Arg His Tyr Cys Arg Glu Asn Thr Met Cys Val Asn Thr Pro Gly 
            500                 505                 510         


Ser Phe Met Cys Ile Cys Lys Thr Gly Tyr Ile Arg Ile Asp Asp Tyr 
        515                 520                 525             


Ser Cys Thr Glu His Asp Glu Cys Ile Thr Asn Gln His Asn Cys Asp 
    530                 535                 540                 


Glu Asn Ala Leu Cys Phe Asn Thr Val Gly Gly His Asn Cys Val Cys 
545                 550                 555                 560 


Lys Pro Gly Tyr Thr Gly Asn Gly Thr Thr Cys Lys Ala Phe Cys Lys 
                565                 570                 575     


Asp Gly Cys Arg Asn Gly Gly Ala Cys Ile Ala Ala Asn Val Cys Ala 
            580                 585                 590         


Cys Pro Gln Gly Phe Thr Gly Pro Ser Cys Glu Thr Asp Ile Asp Glu 
        595                 600                 605             


Cys Ser Asp Gly Phe Val Gln Cys Asp Ser Arg Ala Asn Cys Ile Asn 
    610                 615                 620                 


Leu Pro Gly Trp Tyr His Cys Glu Cys Arg Asp Gly Tyr His Asp Asn 
625                 630                 635                 640 


Gly Met Phe Ser Pro Ser Gly Glu Ser Cys Glu Asp Ile Asp Glu Cys 
                645                 650                 655     


Gly Thr Gly Arg His Ser Cys Ala Asn Asp Thr Ile Cys Phe Asn Leu 
            660                 665                 670         


Asp Gly Gly Tyr Asp Cys Arg Cys Pro His Gly Lys Asn Cys Thr Gly 
        675                 680                 685             


Asp Cys Ile His Asp Gly Lys Val Lys His Asn Gly Gln Ile Trp Val 
    690                 695                 700                 


Leu Glu Asn Asp Arg Cys Ser Val Cys Ser Cys Gln Asn Gly Phe Val 
705                 710                 715                 720 


Met Cys Arg Arg Met Val Cys Asp Cys Glu Asn Pro Thr Val Asp Leu 
                725                 730                 735     


Phe Cys Cys Pro Glu Cys Asp Pro Arg Leu Ser Ser Gln Cys Leu His 
            740                 745                 750         


Gln Asn Gly Glu Thr Leu Tyr Asn Ser Gly Asp Thr Trp Val Gln Asn 
        755                 760                 765             


Cys Gln Gln Cys Arg Cys Leu Gln Gly Glu Val Asp Cys Trp Pro Leu 
    770                 775                 780                 


Pro Cys Pro Asp Val Glu Cys Glu Phe Ser Ile Leu Pro Glu Asn Glu 
785                 790                 795                 800 


Cys Cys Pro Arg Cys Val Thr Asp Pro Cys Gln Ala Asp Thr Ile Arg 
                805                 810                 815     


Asn Asp Ile Thr Lys Thr Cys Leu Asp Glu Met Asn Val Val Arg Phe 
            820                 825                 830         


Thr Gly Ser Ser Trp Ile Lys His Gly Thr Glu Cys Thr Leu Cys Gln 
        835                 840                 845             


Cys Lys Asn Gly His Ile Cys Cys Ser Val Asp Pro Gln Cys Leu Gln 
    850                 855                 860                 


Glu Leu 
865     


<210>  2809
<211>  371
<212>  PRT
<213>  homo sapiens

<400>  2809

Met Glu Leu Glu Gly Gln Trp Trp Arg Gly Gln Leu Ala Ala Asp Ile 
1               5                   10                  15      


His Gln Ala Leu Arg Tyr Lys Glu Leu Lys Leu Pro Ser Tyr Lys Gly 
            20                  25                  30          


Gln Ser Pro Gln Leu Ser Leu Arg Arg Tyr Phe Ala Asp Leu Ile Ala 
        35                  40                  45              


Ile Val Ser Asn Arg Phe Thr Leu Cys Pro Ser Ala Arg His Leu Ala 
    50                  55                  60                  


Val Tyr Leu Leu Asp Leu Phe Met Asp Arg Tyr Asp Ile Ser Ile Gln 
65                  70                  75                  80  


Gln Leu His Leu Val Ala Leu Ser Cys Leu Leu Leu Ala Ser Lys Phe 
                85                  90                  95      


Glu Glu Lys Glu Asp Ser Val Pro Lys Leu Glu Gln Leu Asn Ser Leu 
            100                 105                 110         


Gly Cys Met Thr Asn Met Asn Leu Val Leu Thr Lys Gln Asn Leu Leu 
        115                 120                 125             


His Met Glu Leu Leu Leu Leu Glu Thr Phe Gln Trp Asn Leu Cys Leu 
    130                 135                 140                 


Pro Thr Ala Ala His Phe Ile Glu Tyr Tyr Leu Ser Glu Ala Val His 
145                 150                 155                 160 


Glu Thr Asp Leu His Asp Gly Trp Pro Met Ile Cys Leu Glu Lys Thr 
                165                 170                 175     


Lys Leu Tyr Met Ala Lys Tyr Ala Asp Tyr Phe Leu Glu Val Ser Leu 
            180                 185                 190         


Gln Ala Ala Ala Cys Val Ala Ser Ser Arg Ile Ile Leu Arg Leu Ser 
        195                 200                 205             


Pro Thr Trp Pro Thr Arg Leu His Arg Leu Thr Ala Tyr Ser Trp Asp 
    210                 215                 220                 


Phe Leu Val Gln Cys Ile Glu Arg Leu Leu Ile Ala His Asp Asn Asp 
225                 230                 235                 240 


Val Lys Glu Ala Asn Lys Gln Arg Gly Gln Ala Gly Pro Gln Ser Ala 
                245                 250                 255     


Gln Leu Ser Val Phe Gln Thr Ala Ser Gln Pro Ser Arg Pro Val His 
            260                 265                 270         


Phe Gln Gln Pro Gln Tyr Leu His Gln Thr His Gln Thr Ser Leu Gln 
        275                 280                 285             


Tyr Arg His Pro Thr Ser Glu Gln Pro Ser Cys Gln Gln Ile Val Ser 
    290                 295                 300                 


Thr Thr His Thr Ser Ser Tyr Thr Leu Gln Thr Cys Pro Ala Gly Phe 
305                 310                 315                 320 


Gln Thr Ser Val Gln Gly Leu Gly His Met Gln Thr Gly Val Gly Met 
                325                 330                 335     


Ser Leu Ala Ile Pro Val Glu Val Lys Pro Cys Leu Ser Val Ser Tyr 
            340                 345                 350         


Asn Arg Ser Tyr Gln Ile Asn Glu His Tyr Pro Cys Ile Thr Pro Cys 
        355                 360                 365             


Phe Glu Arg 
    370     


<210>  2810
<211>  635
<212>  PRT
<213>  homo sapiens

<400>  2810

Met Ala Lys Lys Ser Ala Glu Asn Gly Ile Tyr Ser Val Ser Gly Asp 
1               5                   10                  15      


Glu Lys Lys Gly Pro Leu Ile Ala Pro Gly Pro Asp Gly Ala Pro Ala 
            20                  25                  30          


Lys Gly Asp Gly Pro Val Gly Leu Gly Thr Pro Gly Gly Arg Leu Ala 
        35                  40                  45              


Val Pro Pro Arg Glu Thr Trp Thr Arg Gln Met Asp Phe Ile Met Ser 
    50                  55                  60                  


Cys Val Gly Phe Ala Val Gly Leu Gly Asn Val Trp Arg Phe Pro Tyr 
65                  70                  75                  80  


Leu Cys Tyr Lys Asn Gly Gly Gly Val Phe Leu Ile Pro Tyr Val Leu 
                85                  90                  95      


Ile Ala Leu Val Gly Gly Ile Pro Ile Phe Phe Leu Glu Ile Ser Leu 
            100                 105                 110         


Gly Gln Phe Met Lys Ala Gly Ser Ile Asn Val Trp Asn Ile Cys Pro 
        115                 120                 125             


Leu Phe Lys Gly Leu Gly Tyr Ala Ser Met Val Ile Val Phe Tyr Cys 
    130                 135                 140                 


Asn Thr Tyr Tyr Ile Met Val Leu Ala Trp Gly Phe Tyr Tyr Leu Val 
145                 150                 155                 160 


Lys Ser Phe Thr Thr Thr Leu Pro Trp Ala Thr Cys Gly His Thr Trp 
                165                 170                 175     


Asn Thr Pro Asp Cys Val Glu Ile Phe Arg His Glu Asp Cys Ala Asn 
            180                 185                 190         


Ala Ser Leu Ala Asn Leu Thr Cys Asp Gln Leu Ala Asp Arg Arg Ser 
        195                 200                 205             


Pro Val Ile Glu Phe Trp Glu Asn Lys Val Leu Arg Leu Ser Gly Gly 
    210                 215                 220                 


Leu Glu Val Pro Gly Ala Leu Asn Trp Glu Val Thr Leu Cys Leu Leu 
225                 230                 235                 240 


Ala Cys Trp Val Leu Val Tyr Phe Cys Val Trp Lys Gly Val Lys Ser 
                245                 250                 255     


Thr Gly Lys Ile Val Tyr Phe Thr Ala Thr Phe Pro Tyr Val Val Leu 
            260                 265                 270         


Val Val Leu Leu Val Arg Gly Val Leu Leu Pro Gly Ala Leu Asp Gly 
        275                 280                 285             


Ile Ile Tyr Tyr Leu Lys Pro Asp Trp Ser Lys Leu Gly Ser Pro Gln 
    290                 295                 300                 


Val Trp Ile Asp Ala Gly Thr Gln Ile Phe Phe Ser Tyr Ala Ile Gly 
305                 310                 315                 320 


Leu Gly Ala Leu Thr Ala Leu Gly Ser Tyr Asn Arg Phe Asn Asn Asn 
                325                 330                 335     


Cys Tyr Lys Asp Ala Ile Ile Leu Ala Leu Ile Asn Ser Gly Thr Ser 
            340                 345                 350         


Phe Phe Ala Gly Phe Val Val Phe Ser Ile Leu Gly Phe Met Ala Ala 
        355                 360                 365             


Glu Gln Gly Val His Ile Ser Lys Val Ala Glu Ser Gly Pro Gly Leu 
    370                 375                 380                 


Ala Phe Ile Ala Tyr Pro Arg Ala Val Thr Leu Met Pro Val Ala Pro 
385                 390                 395                 400 


Leu Trp Ala Ala Leu Phe Phe Phe Met Leu Leu Leu Leu Gly Leu Asp 
                405                 410                 415     


Ser Gln Phe Val Gly Val Glu Gly Phe Ile Thr Gly Leu Leu Asp Leu 
            420                 425                 430         


Leu Pro Ala Ser Tyr Tyr Phe Arg Phe Gln Arg Glu Ile Ser Val Ala 
        435                 440                 445             


Leu Cys Cys Ala Leu Cys Phe Val Ile Asp Leu Ser Met Val Thr Asp 
    450                 455                 460                 


Gly Gly Met Tyr Val Phe Gln Leu Phe Asp Tyr Tyr Ser Ala Ser Gly 
465                 470                 475                 480 


Thr Thr Leu Leu Trp Gln Ala Phe Trp Glu Cys Val Val Val Ala Trp 
                485                 490                 495     


Val Tyr Gly Ala Asp Arg Phe Met Asp Asp Ile Ala Cys Met Ile Gly 
            500                 505                 510         


Tyr Arg Pro Cys Pro Trp Met Lys Trp Cys Trp Ser Phe Phe Thr Pro 
        515                 520                 525             


Leu Val Cys Met Gly Ile Phe Ile Phe Asn Val Val Tyr Tyr Glu Pro 
    530                 535                 540                 


Leu Val Tyr Asn Asn Thr Tyr Val Tyr Pro Trp Trp Gly Glu Ala Met 
545                 550                 555                 560 


Gly Trp Ala Phe Ala Leu Ser Ser Met Leu Cys Val Pro Leu His Leu 
                565                 570                 575     


Leu Gly Cys Leu Leu Arg Ala Lys Gly Thr Met Ala Glu Arg Trp Gln 
            580                 585                 590         


His Leu Thr Gln Pro Ile Trp Gly Leu His His Leu Glu Tyr Arg Ala 
        595                 600                 605             


Gln Asp Ala Asp Val Arg Gly Leu Thr Thr Leu Thr Pro Val Ser Glu 
    610                 615                 620                 


Ser Ser Lys Val Val Val Val Glu Ser Val Met 
625                 630                 635 


<210>  2811
<211>  198
<212>  PRT
<213>  homo sapiens

<400>  2811

Met Ser Asn Val Arg Val Ser Asn Gly Ser Pro Ser Leu Glu Arg Met 
1               5                   10                  15      


Asp Ala Arg Gln Ala Glu His Pro Lys Pro Ser Ala Cys Arg Asn Leu 
            20                  25                  30          


Phe Gly Pro Val Asp His Glu Glu Leu Thr Arg Asp Leu Glu Lys His 
        35                  40                  45              


Cys Arg Asp Met Glu Glu Ala Ser Gln Arg Lys Trp Asn Phe Asp Phe 
    50                  55                  60                  


Gln Asn His Lys Pro Leu Glu Gly Lys Tyr Glu Trp Gln Glu Val Glu 
65                  70                  75                  80  


Lys Gly Ser Leu Pro Glu Phe Tyr Tyr Arg Pro Pro Arg Pro Pro Lys 
                85                  90                  95      


Gly Ala Cys Lys Val Pro Ala Gln Glu Ser Gln Asp Val Ser Gly Ser 
            100                 105                 110         


Arg Pro Ala Ala Pro Leu Ile Gly Ala Pro Ala Asn Ser Glu Asp Thr 
        115                 120                 125             


His Leu Val Asp Pro Lys Thr Asp Pro Ser Asp Ser Gln Thr Gly Leu 
    130                 135                 140                 


Ala Glu Gln Cys Ala Gly Ile Arg Lys Arg Pro Ala Thr Asp Asp Ser 
145                 150                 155                 160 


Ser Thr Gln Asn Lys Arg Ala Asn Arg Thr Glu Glu Asn Val Ser Asp 
                165                 170                 175     


Gly Ser Pro Asn Ala Gly Ser Val Glu Gln Thr Pro Lys Lys Pro Gly 
            180                 185                 190         


Leu Arg Arg Arg Gln Thr 
        195             


<210>  2812
<211>  509
<212>  PRT
<213>  homo sapiens

<400>  2812

Met Ala Ala Ala Ala Gly Met Leu Leu Leu Gly Leu Leu Gln Ala Gly 
1               5                   10                  15      


Gly Ser Val Leu Gly Gln Ala Met Glu Lys Val Thr Gly Gly Asn Leu 
            20                  25                  30          


Leu Ser Met Leu Leu Ile Ala Cys Ala Phe Thr Leu Ser Leu Val Tyr 
        35                  40                  45              


Leu Ile Arg Leu Ala Ala Gly His Leu Val Gln Leu Pro Ala Gly Val 
    50                  55                  60                  


Lys Ser Pro Pro Tyr Ile Phe Ser Pro Ile Pro Phe Leu Gly His Ala 
65                  70                  75                  80  


Ile Ala Phe Gly Lys Ser Pro Ile Glu Phe Leu Glu Asn Ala Tyr Glu 
                85                  90                  95      


Lys Tyr Gly Pro Val Phe Ser Phe Thr Met Val Gly Lys Thr Phe Thr 
            100                 105                 110         


Tyr Leu Leu Gly Ser Asp Ala Ala Ala Leu Leu Phe Asn Ser Lys Asn 
        115                 120                 125             


Glu Asp Leu Asn Ala Glu Asp Val Tyr Ser Arg Leu Thr Thr Pro Val 
    130                 135                 140                 


Phe Gly Lys Gly Val Ala Tyr Asp Val Pro Asn Pro Val Phe Leu Glu 
145                 150                 155                 160 


Gln Lys Lys Met Leu Lys Ser Gly Leu Asn Ile Ala His Phe Lys Gln 
                165                 170                 175     


His Val Ser Ile Ile Glu Lys Glu Thr Lys Glu Tyr Phe Glu Ser Trp 
            180                 185                 190         


Gly Glu Ser Gly Glu Lys Asn Val Phe Glu Ala Leu Ser Glu Leu Ile 
        195                 200                 205             


Ile Leu Thr Ala Ser His Cys Leu His Gly Lys Glu Ile Arg Ser Gln 
    210                 215                 220                 


Leu Asn Glu Lys Val Ala Gln Leu Tyr Ala Asp Leu Asp Gly Gly Phe 
225                 230                 235                 240 


Ser His Ala Ala Trp Leu Leu Pro Gly Trp Leu Pro Leu Pro Ser Phe 
                245                 250                 255     


Arg Arg Arg Asp Arg Ala His Arg Glu Ile Lys Asp Ile Phe Tyr Lys 
            260                 265                 270         


Ala Ile Gln Lys Arg Arg Gln Ser Gln Glu Lys Ile Asp Asp Ile Leu 
        275                 280                 285             


Gln Thr Leu Leu Asp Ala Thr Tyr Lys Asp Gly Arg Pro Leu Thr Asp 
    290                 295                 300                 


Asp Glu Val Ala Gly Met Leu Ile Gly Leu Leu Leu Ala Gly Gln His 
305                 310                 315                 320 


Thr Ser Ser Thr Thr Ser Ala Trp Met Gly Phe Phe Leu Ala Arg Asp 
                325                 330                 335     


Lys Thr Leu Gln Lys Lys Cys Tyr Leu Glu Gln Lys Thr Val Cys Gly 
            340                 345                 350         


Glu Asn Leu Pro Pro Leu Thr Tyr Asp Gln Leu Lys Asp Leu Asn Leu 
        355                 360                 365             


Leu Asp Arg Cys Ile Lys Glu Thr Leu Arg Leu Arg Pro Pro Ile Met 
    370                 375                 380                 


Ile Met Met Arg Met Ala Arg Thr Pro Gln Thr Val Ala Gly Tyr Thr 
385                 390                 395                 400 


Ile Pro Pro Gly His Gln Val Cys Val Ser Pro Thr Val Asn Gln Arg 
                405                 410                 415     


Leu Lys Asp Ser Trp Val Glu Arg Leu Asp Phe Asn Pro Asp Arg Tyr 
            420                 425                 430         


Leu Gln Asp Asn Pro Ala Ser Gly Glu Lys Phe Ala Tyr Val Pro Phe 
        435                 440                 445             


Gly Ala Gly Arg His Arg Cys Ile Gly Glu Asn Phe Ala Tyr Val Gln 
    450                 455                 460                 


Ile Lys Thr Ile Trp Ser Thr Met Leu Arg Leu Tyr Glu Phe Asp Leu 
465                 470                 475                 480 


Ile Asp Gly Tyr Phe Pro Thr Val Asn Tyr Thr Thr Met Ile His Thr 
                485                 490                 495     


Pro Glu Asn Pro Val Ile Arg Tyr Lys Arg Arg Ser Lys 
            500                 505                 


<210>  2813
<211>  189
<212>  PRT
<213>  homo sapiens

<400>  2813

Met Val Gly Gly Gly Gln Pro Cys Gly Pro Asn Met Ser Glu Val Ser 
1               5                   10                  15      


Cys Lys Lys Arg Asp Asp Tyr Leu Glu Trp Pro Glu Tyr Phe Met Ala 
            20                  25                  30          


Val Ala Phe Leu Ser Ala Gln Arg Ser Lys Asp Pro Asn Ser Gln Val 
        35                  40                  45              


Gly Ala Cys Ile Val Asn Ser Glu Asn Lys Ile Val Gly Ile Gly Tyr 
    50                  55                  60                  


Asn Gly Met Pro Asn Gly Cys Ser Asp Asp Val Leu Pro Trp Arg Arg 
65                  70                  75                  80  


Thr Ala Glu Asn Lys Leu Asp Thr Lys Tyr Pro Tyr Val Cys His Ala 
                85                  90                  95      


Glu Leu Asn Ala Ile Met Asn Lys Asn Ser Thr Asp Val Lys Gly Cys 
            100                 105                 110         


Ser Met Tyr Val Ala Leu Phe Pro Cys Asn Glu Cys Ala Lys Leu Ile 
        115                 120                 125             


Ile Gln Ala Gly Ile Lys Glu Val Ile Phe Met Ser Asp Lys Tyr His 
    130                 135                 140                 


Asp Ser Asp Glu Ala Thr Ala Ala Arg Leu Leu Phe Asn Met Ala Gly 
145                 150                 155                 160 


Val Thr Phe Arg Lys Phe Ile Pro Lys Cys Ser Lys Ile Val Ile Asp 
                165                 170                 175     


Phe Asp Ser Ile Asn Ser Arg Pro Ser Gln Lys Leu Gln 
            180                 185                 


<210>  2814
<211>  763
<212>  PRT
<213>  homo sapiens

<400>  2814

Met Asp His Leu Asn Glu Ala Thr Gln Gly Lys Glu His Ser Glu Met 
1               5                   10                  15      


Ser Asn Asn Val Ser Asp Pro Lys Gly Pro Pro Ala Lys Ile Ala Arg 
            20                  25                  30          


Leu Glu Gln Asn Gly Ser Pro Leu Gly Arg Gly Arg Leu Gly Ser Thr 
        35                  40                  45              


Gly Ala Lys Met Gln Gly Val Pro Leu Lys His Ser Gly His Leu Met 
    50                  55                  60                  


Lys Thr Asn Leu Arg Lys Gly Thr Met Leu Pro Val Phe Cys Val Val 
65                  70                  75                  80  


Glu His Tyr Glu Asn Ala Ile Glu Tyr Asp Cys Lys Glu Glu His Ala 
                85                  90                  95      


Glu Phe Val Leu Val Arg Lys Asp Met Leu Phe Asn Gln Leu Ile Glu 
            100                 105                 110         


Met Ala Leu Leu Ser Leu Gly Tyr Ser His Ser Ser Ala Ala Gln Ala 
        115                 120                 125             


Lys Gly Leu Ile Gln Val Gly Lys Trp Asn Pro Val Pro Leu Ser Tyr 
    130                 135                 140                 


Val Thr Asp Ala Pro Asp Ala Thr Val Ala Asp Met Leu Gln Asp Val 
145                 150                 155                 160 


Tyr His Val Val Thr Leu Lys Ile Gln Leu His Ser Cys Pro Lys Leu 
                165                 170                 175     


Glu Asp Leu Pro Pro Glu Gln Trp Ser His Thr Thr Val Arg Asn Ala 
            180                 185                 190         


Leu Lys Asp Leu Leu Lys Asp Met Asn Gln Ser Ser Leu Ala Lys Glu 
        195                 200                 205             


Cys Pro Leu Ser Gln Ser Met Ile Ser Ser Ile Val Asn Ser Thr Tyr 
    210                 215                 220                 


Tyr Ala Asn Val Ser Ala Ala Lys Cys Gln Glu Phe Gly Arg Trp Tyr 
225                 230                 235                 240 


Lys His Phe Lys Lys Thr Lys Asp Met Met Val Glu Met Asp Ser Leu 
                245                 250                 255     


Ser Glu Leu Ser Gln Gln Gly Ala Asn His Val Asn Phe Gly Gln Gln 
            260                 265                 270         


Pro Val Pro Gly Asn Thr Ala Glu Gln Pro Pro Ser Pro Ala Gln Leu 
        275                 280                 285             


Ser His Gly Ser Gln Pro Ser Val Arg Thr Pro Leu Pro Asn Leu His 
    290                 295                 300                 


Pro Gly Leu Val Ser Thr Pro Ile Ser Pro Gln Leu Val Asn Gln Gln 
305                 310                 315                 320 


Leu Val Met Ala Gln Leu Leu Asn Gln Gln Tyr Ala Val Asn Arg Leu 
                325                 330                 335     


Leu Ala Gln Gln Ser Leu Asn Gln Gln Tyr Leu Asn His Pro Pro Pro 
            340                 345                 350         


Val Ser Arg Ser Met Asn Lys Pro Leu Glu Gln Gln Val Ser Thr Asn 
        355                 360                 365             


Thr Glu Val Ser Ser Glu Ile Tyr Gln Trp Val Arg Asp Glu Leu Lys 
    370                 375                 380                 


Arg Ala Gly Ile Ser Gln Ala Val Phe Ala Arg Val Ala Phe Asn Arg 
385                 390                 395                 400 


Thr Gln Gly Leu Leu Ser Glu Ile Leu Arg Lys Glu Glu Asp Pro Lys 
                405                 410                 415     


Thr Ala Ser Gln Ser Leu Leu Val Asn Leu Arg Ala Met Gln Asn Phe 
            420                 425                 430         


Leu Gln Leu Pro Glu Ala Glu Arg Asp Arg Ile Tyr Gln Asp Glu Arg 
        435                 440                 445             


Glu Arg Ser Leu Asn Ala Ala Ser Ala Met Gly Pro Ala Pro Leu Ile 
    450                 455                 460                 


Ser Thr Pro Pro Ser Arg Pro Pro Gln Val Lys Thr Ala Thr Ile Ala 
465                 470                 475                 480 


Thr Glu Arg Asn Gly Lys Pro Glu Asn Asn Thr Met Asn Ile Asn Ala 
                485                 490                 495     


Ser Ile Tyr Asp Glu Ile Gln Gln Glu Met Lys Arg Ala Lys Val Ser 
            500                 505                 510         


Gln Ala Leu Phe Ala Lys Val Ala Ala Thr Lys Ser Gln Gly Trp Leu 
        515                 520                 525             


Cys Glu Leu Leu Arg Trp Lys Glu Asp Pro Ser Pro Glu Asn Arg Thr 
    530                 535                 540                 


Leu Trp Glu Asn Leu Ser Met Ile Arg Arg Phe Leu Ser Leu Pro Gln 
545                 550                 555                 560 


Pro Glu Arg Asp Ala Ile Tyr Glu Gln Glu Ser Asn Ala Val His His 
                565                 570                 575     


His Gly Asp Arg Pro Pro His Ile Ile His Val Pro Ala Glu Gln Ile 
            580                 585                 590         


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Ala 
        595                 600                 605             


Pro Pro Pro Pro Gln Pro Gln Gln Gln Pro Gln Thr Gly Pro Arg Leu 
    610                 615                 620                 


Pro Pro Arg Gln Pro Thr Val Ala Ser Pro Ala Glu Ser Asp Glu Glu 
625                 630                 635                 640 


Asn Arg Gln Lys Thr Arg Pro Arg Thr Lys Ile Ser Val Glu Ala Leu 
                645                 650                 655     


Gly Ile Leu Gln Ser Phe Ile Gln Asp Val Gly Leu Tyr Pro Asp Glu 
            660                 665                 670         


Glu Ala Ile Gln Thr Leu Ser Ala Gln Leu Asp Leu Pro Lys Tyr Thr 
        675                 680                 685             


Ile Ile Lys Phe Phe Gln Asn Gln Arg Tyr Tyr Leu Lys His His Gly 
    690                 695                 700                 


Lys Leu Lys Asp Asn Ser Gly Leu Glu Val Asp Val Ala Glu Tyr Lys 
705                 710                 715                 720 


Glu Glu Glu Leu Leu Lys Asp Leu Glu Glu Ser Val Gln Asp Lys Asn 
                725                 730                 735     


Thr Asn Thr Leu Phe Ser Val Lys Leu Glu Glu Glu Leu Ser Val Glu 
            740                 745                 750         


Gly Asn Thr Asp Ile Asn Thr Asp Leu Lys Asp 
        755                 760             


<210>  2815
<211>  763
<212>  PRT
<213>  homo sapiens

<400>  2815

Met Asp His Leu Asn Glu Ala Thr Gln Gly Lys Glu His Ser Glu Met 
1               5                   10                  15      


Ser Asn Asn Val Ser Asp Pro Lys Gly Pro Pro Ala Lys Ile Ala Arg 
            20                  25                  30          


Leu Glu Gln Asn Gly Ser Pro Leu Gly Arg Gly Arg Leu Gly Ser Thr 
        35                  40                  45              


Gly Ala Lys Met Gln Gly Val Pro Leu Lys His Ser Gly His Leu Met 
    50                  55                  60                  


Lys Thr Asn Leu Arg Lys Gly Thr Met Leu Pro Val Phe Cys Val Val 
65                  70                  75                  80  


Glu His Tyr Glu Asn Ala Ile Glu Tyr Asp Cys Lys Glu Glu His Ala 
                85                  90                  95      


Glu Phe Val Leu Val Arg Lys Asp Met Leu Phe Asn Gln Leu Ile Glu 
            100                 105                 110         


Met Ala Leu Leu Ser Leu Gly Tyr Ser His Ser Ser Ala Ala Gln Ala 
        115                 120                 125             


Lys Gly Leu Ile Gln Val Gly Lys Trp Asn Pro Val Pro Leu Ser Tyr 
    130                 135                 140                 


Val Thr Asp Ala Pro Asp Ala Thr Val Ala Asp Met Leu Gln Asp Val 
145                 150                 155                 160 


Tyr His Val Val Thr Leu Lys Ile Gln Leu His Ser Cys Pro Lys Leu 
                165                 170                 175     


Glu Asp Leu Pro Pro Glu Gln Trp Ser His Thr Thr Val Arg Asn Ala 
            180                 185                 190         


Leu Lys Asp Leu Leu Lys Asp Met Asn Gln Ser Ser Leu Ala Lys Glu 
        195                 200                 205             


Cys Pro Leu Ser Gln Ser Met Ile Ser Ser Ile Val Asn Ser Thr Tyr 
    210                 215                 220                 


Tyr Ala Asn Val Ser Ala Ala Lys Cys Gln Glu Phe Gly Arg Trp Tyr 
225                 230                 235                 240 


Lys His Phe Lys Lys Thr Lys Asp Met Met Val Glu Met Asp Ser Leu 
                245                 250                 255     


Ser Glu Leu Ser Gln Gln Gly Ala Asn His Val Asn Phe Gly Gln Gln 
            260                 265                 270         


Pro Val Pro Gly Asn Thr Ala Glu Gln Pro Pro Ser Pro Ala Gln Leu 
        275                 280                 285             


Ser His Gly Ser Gln Pro Ser Val Arg Thr Pro Leu Pro Asn Leu His 
    290                 295                 300                 


Pro Gly Leu Val Ser Thr Pro Ile Ser Pro Gln Leu Val Asn Gln Gln 
305                 310                 315                 320 


Leu Val Met Ala Gln Leu Leu Asn Gln Gln Tyr Ala Val Asn Arg Leu 
                325                 330                 335     


Leu Ala Gln Gln Ser Leu Asn Gln Gln Tyr Leu Asn His Pro Pro Pro 
            340                 345                 350         


Val Ser Arg Ser Met Asn Lys Pro Leu Glu Gln Gln Val Ser Thr Asn 
        355                 360                 365             


Thr Glu Val Ser Ser Glu Ile Tyr Gln Trp Val Arg Asp Glu Leu Lys 
    370                 375                 380                 


Arg Ala Gly Ile Ser Gln Ala Val Phe Ala Arg Val Ala Phe Asn Arg 
385                 390                 395                 400 


Thr Gln Gly Leu Leu Ser Glu Ile Leu Arg Lys Glu Glu Asp Pro Lys 
                405                 410                 415     


Thr Ala Ser Gln Ser Leu Leu Val Asn Leu Arg Ala Met Gln Asn Phe 
            420                 425                 430         


Leu Gln Leu Pro Glu Ala Glu Arg Asp Arg Ile Tyr Gln Asp Glu Arg 
        435                 440                 445             


Glu Arg Ser Leu Asn Ala Ala Ser Ala Met Gly Pro Ala Pro Leu Ile 
    450                 455                 460                 


Ser Thr Pro Pro Ser Arg Pro Pro Gln Val Lys Thr Ala Thr Ile Ala 
465                 470                 475                 480 


Thr Glu Arg Asn Gly Lys Pro Glu Asn Asn Thr Met Asn Ile Asn Ala 
                485                 490                 495     


Ser Ile Tyr Asp Glu Ile Gln Gln Glu Met Lys Arg Ala Lys Val Ser 
            500                 505                 510         


Gln Ala Leu Phe Ala Lys Val Ala Ala Thr Lys Ser Gln Gly Trp Leu 
        515                 520                 525             


Cys Glu Leu Leu Arg Trp Lys Glu Asp Pro Ser Pro Glu Asn Arg Thr 
    530                 535                 540                 


Leu Trp Glu Asn Leu Ser Met Ile Arg Arg Phe Leu Ser Leu Pro Gln 
545                 550                 555                 560 


Pro Glu Arg Asp Ala Ile Tyr Glu Gln Glu Ser Asn Ala Val His His 
                565                 570                 575     


His Gly Asp Arg Pro Pro His Ile Ile His Val Pro Ala Glu Gln Ile 
            580                 585                 590         


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Ala 
        595                 600                 605             


Pro Pro Pro Pro Gln Pro Gln Gln Gln Pro Gln Thr Gly Pro Arg Leu 
    610                 615                 620                 


Pro Pro Arg Gln Pro Thr Val Ala Ser Pro Ala Glu Ser Asp Glu Glu 
625                 630                 635                 640 


Asn Arg Gln Lys Thr Arg Pro Arg Thr Lys Ile Ser Val Glu Ala Leu 
                645                 650                 655     


Gly Ile Leu Gln Ser Phe Ile Gln Asp Val Gly Leu Tyr Pro Asp Glu 
            660                 665                 670         


Glu Ala Ile Gln Thr Leu Ser Ala Gln Leu Asp Leu Pro Lys Tyr Thr 
        675                 680                 685             


Ile Ile Lys Phe Phe Gln Asn Gln Arg Tyr Tyr Leu Lys His His Gly 
    690                 695                 700                 


Lys Leu Lys Asp Asn Ser Gly Leu Glu Val Asp Val Ala Glu Tyr Lys 
705                 710                 715                 720 


Glu Glu Glu Leu Leu Lys Asp Leu Glu Glu Ser Val Gln Asp Lys Asn 
                725                 730                 735     


Thr Asn Thr Leu Phe Ser Val Lys Leu Glu Glu Glu Leu Ser Val Glu 
            740                 745                 750         


Gly Asn Thr Asp Ile Asn Thr Asp Leu Lys Asp 
        755                 760             


<210>  2816
<211>  1382
<212>  PRT
<213>  homo sapiens

<400>  2816

Met Pro Ala Tyr Phe Gln Arg Pro Glu Asn Ala Leu Lys Arg Ala Asn 
1               5                   10                  15      


Glu Phe Leu Glu Val Gly Lys Lys Gln Pro Ala Leu Asp Val Leu Tyr 
            20                  25                  30          


Asp Val Met Lys Ser Lys Lys His Arg Thr Trp Gln Lys Ile His Glu 
        35                  40                  45              


Pro Ile Met Leu Lys Tyr Leu Glu Leu Cys Val Asp Leu Arg Lys Ser 
    50                  55                  60                  


His Leu Ala Lys Glu Gly Leu Tyr Gln Tyr Lys Asn Ile Cys Gln Gln 
65                  70                  75                  80  


Val Asn Ile Lys Ser Leu Glu Asp Val Val Arg Ala Tyr Leu Lys Met 
                85                  90                  95      


Ala Glu Glu Lys Thr Glu Ala Ala Lys Glu Glu Ser Gln Gln Met Val 
            100                 105                 110         


Leu Asp Ile Glu Asp Leu Asp Asn Ile Gln Thr Pro Glu Ser Val Leu 
        115                 120                 125             


Leu Ser Ala Val Ser Gly Glu Asp Thr Gln Asp Arg Thr Asp Arg Leu 
    130                 135                 140                 


Leu Leu Thr Pro Trp Val Lys Phe Leu Trp Glu Ser Tyr Arg Gln Cys 
145                 150                 155                 160 


Leu Asp Leu Leu Arg Asn Asn Ser Arg Val Glu Arg Leu Tyr His Asp 
                165                 170                 175     


Ile Ala Gln Gln Ala Phe Lys Phe Cys Leu Gln Tyr Thr Arg Lys Ala 
            180                 185                 190         


Glu Phe Arg Lys Leu Cys Asp Asn Leu Arg Met His Leu Ser Gln Ile 
        195                 200                 205             


Gln Arg His His Asn Gln Ser Thr Ala Ile Asn Leu Asn Asn Pro Glu 
    210                 215                 220                 


Ser Gln Ser Met His Leu Glu Thr Arg Leu Val Gln Leu Asp Ser Ala 
225                 230                 235                 240 


Ile Ser Met Glu Leu Trp Gln Glu Ala Phe Lys Ala Val Glu Asp Ile 
                245                 250                 255     


His Gly Leu Phe Ser Leu Ser Lys Lys Pro Pro Lys Pro Gln Leu Met 
            260                 265                 270         


Ala Asn Tyr Tyr Asn Lys Val Ser Thr Val Phe Trp Lys Ser Gly Asn 
        275                 280                 285             


Ala Leu Phe His Ala Ser Thr Leu His Arg Leu Tyr His Leu Ser Arg 
    290                 295                 300                 


Glu Met Arg Lys Asn Leu Thr Gln Asp Glu Met Gln Arg Met Ser Thr 
305                 310                 315                 320 


Arg Val Leu Leu Ala Thr Leu Ser Ile Pro Ile Thr Pro Glu Arg Thr 
                325                 330                 335     


Asp Ile Ala Arg Leu Leu Asp Met Asp Gly Ile Ile Val Glu Lys Gln 
            340                 345                 350         


Arg Arg Leu Ala Thr Leu Leu Gly Leu Gln Ala Pro Pro Thr Arg Ile 
        355                 360                 365             


Gly Leu Ile Asn Asp Met Val Arg Phe Asn Val Leu Gln Tyr Val Val 
    370                 375                 380                 


Pro Glu Val Lys Asp Leu Tyr Asn Trp Leu Glu Val Glu Phe Asn Pro 
385                 390                 395                 400 


Leu Lys Leu Cys Glu Arg Val Thr Lys Val Leu Asn Trp Val Arg Glu 
                405                 410                 415     


Gln Pro Glu Lys Glu Pro Glu Leu Gln Gln Tyr Val Pro Gln Leu Gln 
            420                 425                 430         


Asn Asn Thr Ile Leu Arg Leu Leu Gln Gln Val Ser Gln Ile Tyr Gln 
        435                 440                 445             


Ser Ile Glu Phe Ser Arg Leu Thr Ser Leu Val Pro Phe Val Asp Ala 
    450                 455                 460                 


Phe Gln Leu Glu Arg Ala Ile Val Asp Ala Ala Arg His Cys Asp Leu 
465                 470                 475                 480 


Gln Val Arg Ile Asp His Thr Ser Arg Thr Leu Ser Phe Gly Ser Asp 
                485                 490                 495     


Leu Asn Tyr Ala Thr Arg Glu Asp Ala Pro Ile Gly Pro His Leu Gln 
            500                 505                 510         


Ser Met Pro Ser Glu Gln Ile Arg Asn Gln Leu Thr Ala Met Ser Ser 
        515                 520                 525             


Val Leu Ala Lys Ala Leu Glu Val Ile Lys Pro Ala His Ile Leu Gln 
    530                 535                 540                 


Glu Lys Glu Glu Gln His Gln Leu Ala Val Thr Ala Tyr Leu Lys Asn 
545                 550                 555                 560 


Ser Arg Lys Glu His Gln Arg Ile Leu Ala Arg Arg Gln Thr Ile Glu 
                565                 570                 575     


Glu Arg Lys Glu Arg Leu Glu Ser Leu Asn Ile Gln Arg Glu Lys Glu 
            580                 585                 590         


Glu Leu Glu Gln Arg Glu Ala Glu Leu Gln Lys Val Arg Lys Ala Glu 
        595                 600                 605             


Glu Glu Arg Leu Arg Gln Glu Ala Lys Glu Arg Glu Lys Glu Arg Ile 
    610                 615                 620                 


Leu Gln Glu His Glu Gln Ile Lys Lys Lys Thr Val Arg Glu Arg Leu 
625                 630                 635                 640 


Glu Gln Ile Lys Lys Thr Glu Leu Gly Ala Lys Ala Phe Lys Asp Ile 
                645                 650                 655     


Asp Ile Glu Asp Leu Glu Glu Leu Asp Pro Asp Phe Ile Met Ala Lys 
            660                 665                 670         


Gln Val Glu Gln Leu Glu Lys Glu Lys Lys Glu Leu Gln Glu Arg Leu 
        675                 680                 685             


Lys Asn Gln Glu Lys Lys Ile Asp Tyr Phe Glu Arg Ala Lys Arg Leu 
    690                 695                 700                 


Glu Glu Ile Pro Leu Ile Lys Ser Ala Tyr Glu Glu Gln Arg Ile Lys 
705                 710                 715                 720 


Asp Met Asp Leu Trp Glu Gln Gln Glu Glu Glu Arg Ile Thr Thr Met 
                725                 730                 735     


Gln Leu Glu Arg Glu Lys Ala Leu Glu His Lys Asn Arg Met Ser Arg 
            740                 745                 750         


Met Leu Glu Asp Arg Asp Leu Phe Val Met Arg Leu Lys Ala Ala Arg 
        755                 760                 765             


Gln Ser Val Tyr Glu Glu Lys Leu Lys Gln Phe Glu Glu Arg Leu Ala 
    770                 775                 780                 


Glu Glu Arg His Asn Arg Leu Glu Glu Arg Lys Arg Gln Arg Lys Glu 
785                 790                 795                 800 


Glu Arg Arg Ile Thr Tyr Tyr Arg Glu Lys Glu Glu Glu Glu Gln Arg 
                805                 810                 815     


Arg Ala Glu Glu Gln Met Leu Lys Glu Arg Glu Glu Arg Glu Arg Ala 
            820                 825                 830         


Glu Arg Ala Lys Arg Glu Glu Glu Leu Arg Glu Tyr Gln Glu Arg Val 
        835                 840                 845             


Lys Lys Leu Glu Glu Val Glu Arg Lys Lys Arg Gln Arg Glu Leu Glu 
    850                 855                 860                 


Ile Glu Glu Arg Glu Arg Arg Arg Glu Glu Glu Arg Arg Leu Gly Asp 
865                 870                 875                 880 


Ser Ser Leu Ser Arg Lys Asp Ser Arg Trp Gly Asp Arg Asp Ser Glu 
                885                 890                 895     


Gly Thr Trp Arg Lys Gly Pro Glu Ala Asp Ser Glu Trp Arg Arg Gly 
            900                 905                 910         


Pro Pro Glu Lys Glu Trp Arg Arg Gly Glu Gly Arg Asp Glu Asp Arg 
        915                 920                 925             


Ser His Arg Arg Asp Glu Glu Arg Pro Arg Arg Leu Gly Asp Asp Glu 
    930                 935                 940                 


Asp Arg Glu Pro Ser Leu Arg Pro Asp Asp Asp Arg Val Pro Arg Arg 
945                 950                 955                 960 


Gly Met Asp Asp Asp Arg Gly Pro Arg Arg Gly Pro Glu Glu Asp Arg 
                965                 970                 975     


Phe Ser Arg Arg Gly Ala Asp Asp Asp Arg Pro Ser Trp Arg Asn Thr 
            980                 985                 990         


Asp Asp Asp Arg Pro Pro Arg Arg  Ile Ala Asp Glu Asp  Arg Gly Asn 
        995                 1000                 1005             


Trp Arg  His Ala Asp Asp Asp  Arg Pro Pro Arg Arg  Gly Leu Asp 
    1010                 1015                 1020             


Glu Asp  Arg Gly Ser Trp Arg  Thr Ala Asp Glu Asp  Arg Gly Pro 
    1025                 1030                 1035             


Arg Arg  Gly Met Asp Asp Asp  Arg Gly Pro Arg Arg  Gly Gly Ala 
    1040                 1045                 1050             


Asp Asp  Glu Arg Ser Ser Trp  Arg Asn Ala Asp Asp  Asp Arg Gly 
    1055                 1060                 1065             


Pro Arg  Arg Gly Leu Asp Asp  Asp Arg Gly Pro Arg  Arg Gly Met 
    1070                 1075                 1080             


Asp Asp  Asp Arg Gly Pro Arg  Arg Gly Met Asp Asp  Asp Arg Gly 
    1085                 1090                 1095             


Pro Arg  Arg Gly Met Asp Asp  Asp Arg Gly Pro Arg  Arg Gly Leu 
    1100                 1105                 1110             


Asp Asp  Asp Arg Gly Pro Trp  Arg Asn Ala Asp Asp  Asp Arg Ile 
    1115                 1120                 1125             


Pro Arg  Arg Gly Ala Glu Asp  Asp Arg Gly Pro Trp  Arg Asn Met 
    1130                 1135                 1140             


Asp Asp  Asp Arg Leu Ser Arg  Arg Ala Asp Asp Asp  Arg Phe Pro 
    1145                 1150                 1155             


Arg Arg  Gly Asp Asp Ser Arg  Pro Gly Pro Trp Arg  Pro Leu Val 
    1160                 1165                 1170             


Lys Pro  Gly Gly Trp Arg Glu  Lys Glu Lys Ala Arg  Glu Glu Ser 
    1175                 1180                 1185             


Trp Gly  Pro Pro Arg Glu Ser  Arg Pro Ser Glu Glu  Arg Glu Trp 
    1190                 1195                 1200             


Asp Arg  Glu Lys Glu Arg Asp  Arg Asp Asn Gln Asp  Arg Glu Glu 
    1205                 1210                 1215             


Asn Asp  Lys Asp Pro Glu Arg  Glu Arg Asp Arg Glu  Arg Asp Val 
    1220                 1225                 1230             


Asp Arg  Glu Asp Arg Phe Arg  Arg Pro Arg Asp Glu  Gly Gly Trp 
    1235                 1240                 1245             


Arg Arg  Gly Pro Ala Glu Glu  Ser Ser Ser Trp Arg  Asp Ser Ser 
    1250                 1255                 1260             


Arg Arg  Asp Asp Arg Asp Arg  Asp Asp Arg Arg Arg  Glu Arg Asp 
    1265                 1270                 1275             


Asp Arg  Arg Asp Leu Arg Glu  Arg Arg Asp Leu Arg  Asp Asp Arg 
    1280                 1285                 1290             


Asp Arg  Arg Gly Pro Pro Leu  Arg Ser Glu Arg Glu  Glu Val Ser 
    1295                 1300                 1305             


Ser Trp  Arg Arg Ala Asp Asp  Arg Lys Asp Asp Arg  Val Glu Glu 
    1310                 1315                 1320             


Arg Asp  Pro Pro Arg Arg Val  Pro Pro Pro Ala Leu  Ser Arg Asp 
    1325                 1330                 1335             


Arg Glu  Arg Asp Arg Asp Arg  Glu Arg Glu Gly Glu  Lys Glu Lys 
    1340                 1345                 1350             


Ala Ser  Trp Arg Ala Glu Lys  Asp Arg Glu Ser Leu  Arg Arg Thr 
    1355                 1360                 1365             


Lys Asn  Glu Thr Asp Glu Asp  Gly Trp Thr Thr Val  Arg Arg 
    1370                 1375                 1380         


<210>  2817
<211>  1240
<212>  PRT
<213>  homo sapiens

<400>  2817

Met Ala Arg Gln Pro Pro Pro Pro Trp Val His Ala Ala Phe Leu Leu 
1               5                   10                  15      


Cys Leu Leu Ser Leu Gly Gly Ala Ile Glu Ile Pro Met Asp Pro Ser 
            20                  25                  30          


Ile Gln Asn Glu Leu Thr Gln Pro Pro Thr Ile Thr Lys Gln Ser Ala 
        35                  40                  45              


Lys Asp His Ile Val Asp Pro Arg Asp Asn Ile Leu Ile Glu Cys Glu 
    50                  55                  60                  


Ala Lys Gly Asn Pro Ala Pro Ser Phe His Trp Thr Arg Asn Ser Arg 
65                  70                  75                  80  


Phe Phe Asn Ile Ala Lys Asp Pro Arg Val Ser Met Arg Arg Arg Ser 
                85                  90                  95      


Gly Thr Leu Val Ile Asp Phe Arg Ser Gly Gly Arg Pro Glu Glu Tyr 
            100                 105                 110         


Glu Gly Glu Tyr Gln Cys Phe Ala Arg Asn Lys Phe Gly Thr Ala Leu 
        115                 120                 125             


Ser Asn Arg Ile Arg Leu Gln Val Ser Lys Ser Pro Leu Trp Pro Lys 
    130                 135                 140                 


Glu Asn Leu Asp Pro Val Val Val Gln Glu Gly Ala Pro Leu Thr Leu 
145                 150                 155                 160 


Gln Cys Asn Pro Pro Pro Gly Leu Pro Ser Pro Val Ile Phe Trp Met 
                165                 170                 175     


Ser Ser Ser Met Glu Pro Ile Thr Gln Asp Lys Arg Val Ser Gln Gly 
            180                 185                 190         


His Asn Gly Asp Leu Tyr Phe Ser Asn Val Met Leu Gln Asp Met Gln 
        195                 200                 205             


Thr Asp Tyr Ser Cys Asn Ala Arg Phe His Phe Thr His Thr Ile Gln 
    210                 215                 220                 


Gln Lys Asn Pro Phe Thr Leu Lys Val Leu Thr Thr Arg Gly Val Ala 
225                 230                 235                 240 


Glu Arg Thr Pro Ser Phe Met Tyr Pro Gln Gly Thr Ala Ser Ser Gln 
                245                 250                 255     


Met Val Leu Arg Gly Met Asp Leu Leu Leu Glu Cys Ile Ala Ser Gly 
            260                 265                 270         


Val Pro Thr Pro Asp Ile Ala Trp Tyr Lys Lys Gly Gly Asp Leu Pro 
        275                 280                 285             


Ser Asp Lys Ala Lys Phe Glu Asn Phe Asn Lys Ala Leu Arg Ile Thr 
    290                 295                 300                 


Asn Val Ser Glu Glu Asp Ser Gly Glu Tyr Phe Cys Leu Ala Ser Asn 
305                 310                 315                 320 


Lys Met Gly Ser Ile Arg His Thr Ile Ser Val Arg Val Lys Ala Ala 
                325                 330                 335     


Pro Tyr Trp Leu Asp Glu Pro Lys Asn Leu Ile Leu Ala Pro Gly Glu 
            340                 345                 350         


Asp Gly Arg Leu Val Cys Arg Ala Asn Gly Asn Pro Lys Pro Thr Val 
        355                 360                 365             


Gln Trp Met Val Asn Gly Glu Pro Leu Gln Ser Ala Pro Pro Asn Pro 
    370                 375                 380                 


Asn Arg Glu Val Ala Gly Asp Thr Ile Ile Phe Arg Asp Thr Gln Ile 
385                 390                 395                 400 


Ser Ser Arg Ala Val Tyr Gln Cys Asn Thr Ser Asn Glu His Gly Tyr 
                405                 410                 415     


Leu Leu Ala Asn Ala Phe Val Ser Val Leu Asp Val Pro Pro Arg Met 
            420                 425                 430         


Leu Ser Pro Arg Asn Gln Leu Ile Arg Val Ile Leu Tyr Asn Arg Thr 
        435                 440                 445             


Arg Leu Asp Cys Pro Phe Phe Gly Ser Pro Ile Pro Thr Leu Arg Trp 
    450                 455                 460                 


Phe Lys Asn Gly Gln Gly Ser Asn Leu Asp Gly Gly Asn Tyr His Val 
465                 470                 475                 480 


Tyr Glu Asn Gly Ser Leu Glu Ile Lys Met Ile Arg Lys Glu Asp Gln 
                485                 490                 495     


Gly Ile Tyr Thr Cys Val Ala Thr Asn Ile Leu Gly Lys Ala Glu Asn 
            500                 505                 510         


Gln Val Arg Leu Glu Val Lys Asp Pro Thr Arg Ile Tyr Arg Met Pro 
        515                 520                 525             


Glu Asp Gln Val Ala Arg Arg Gly Thr Thr Val Gln Leu Glu Cys Arg 
    530                 535                 540                 


Val Lys His Asp Pro Ser Leu Lys Leu Thr Val Ser Trp Leu Lys Asp 
545                 550                 555                 560 


Asp Glu Pro Leu Tyr Ile Gly Asn Arg Met Lys Lys Glu Asp Asp Ser 
                565                 570                 575     


Leu Thr Ile Phe Gly Val Ala Glu Arg Asp Gln Gly Ser Tyr Thr Cys 
            580                 585                 590         


Val Ala Ser Thr Glu Leu Asp Gln Asp Leu Ala Lys Ala Tyr Leu Thr 
        595                 600                 605             


Val Leu Ala Asp Gln Ala Thr Pro Thr Asn Arg Leu Ala Ala Leu Pro 
    610                 615                 620                 


Lys Gly Arg Pro Asp Arg Pro Arg Asp Leu Glu Leu Thr Asp Leu Ala 
625                 630                 635                 640 


Glu Arg Ser Val Arg Leu Thr Trp Ile Pro Gly Asp Ala Asn Asn Ser 
                645                 650                 655     


Pro Ile Thr Asp Tyr Val Val Gln Phe Glu Glu Asp Gln Phe Gln Pro 
            660                 665                 670         


Gly Val Trp His Asp His Ser Lys Tyr Pro Gly Ser Val Asn Ser Ala 
        675                 680                 685             


Val Leu Arg Leu Ser Pro Tyr Val Asn Tyr Gln Phe Arg Val Ile Ala 
    690                 695                 700                 


Ile Asn Glu Val Gly Ser Ser His Pro Ser Leu Pro Ser Glu Arg Tyr 
705                 710                 715                 720 


Arg Thr Ser Gly Ala Pro Pro Glu Ser Asn Pro Gly Asp Val Lys Gly 
                725                 730                 735     


Glu Gly Thr Arg Lys Asn Asn Met Glu Ile Thr Trp Thr Pro Met Asn 
            740                 745                 750         


Ala Thr Ser Ala Phe Gly Pro Asn Leu Arg Tyr Ile Val Lys Trp Arg 
        755                 760                 765             


Arg Arg Glu Thr Arg Glu Ala Trp Asn Asn Val Thr Val Trp Gly Ser 
    770                 775                 780                 


Arg Tyr Val Val Gly Gln Thr Pro Val Tyr Val Pro Tyr Glu Ile Arg 
785                 790                 795                 800 


Val Gln Ala Glu Asn Asp Phe Gly Lys Gly Pro Glu Pro Glu Ser Val 
                805                 810                 815     


Ile Gly Tyr Ser Gly Glu Asp Leu Pro Ser Ala Pro Arg Arg Phe Arg 
            820                 825                 830         


Val Arg Gln Pro Asn Leu Glu Thr Ile Asn Leu Glu Trp Asp His Pro 
        835                 840                 845             


Glu His Pro Asn Gly Ile Met Ile Gly Tyr Thr Leu Lys Tyr Val Ala 
    850                 855                 860                 


Phe Asn Gly Thr Lys Val Gly Lys Gln Ile Val Glu Asn Phe Ser Pro 
865                 870                 875                 880 


Asn Gln Thr Lys Phe Thr Val Gln Arg Thr Asp Pro Val Ser Arg Tyr 
                885                 890                 895     


Arg Phe Thr Leu Ser Ala Arg Thr Gln Val Gly Ser Gly Glu Ala Val 
            900                 905                 910         


Thr Glu Glu Ser Pro Ala Pro Pro Asn Glu Ala Thr Pro Thr Ala Ala 
        915                 920                 925             


Pro Pro Thr Leu Pro Pro Thr Thr Val Gly Ala Thr Gly Ala Val Ser 
    930                 935                 940                 


Ser Thr Asp Ala Thr Ala Ile Ala Ala Thr Thr Glu Ala Thr Thr Val 
945                 950                 955                 960 


Pro Ile Ile Pro Thr Val Ala Pro Thr Thr Ile Ala Thr Thr Thr Thr 
                965                 970                 975     


Val Ala Thr Thr Thr Thr Thr Thr Ala Ala Ala Thr Thr Thr Thr Glu 
            980                 985                 990         


Ser Pro Pro Thr Thr Thr Ser Gly  Thr Lys Ile His Glu  Ser Ala Pro 
        995                 1000                 1005             


Asp Glu  Gln Ser Ile Trp Asn  Val Thr Val Leu Pro  Asn Ser Lys 
    1010                 1015                 1020             


Trp Ala  Asn Ile Thr Trp Lys  His Asn Phe Gly Pro  Gly Thr Asp 
    1025                 1030                 1035             


Phe Val  Val Glu Tyr Ile Asp  Ser Asn His Thr Lys  Lys Thr Val 
    1040                 1045                 1050             


Pro Val  Lys Ala Gln Ala Gln  Pro Ile Gln Leu Thr  Asp Leu Tyr 
    1055                 1060                 1065             


Pro Gly  Met Thr Tyr Thr Leu  Arg Val Tyr Ser Arg  Asp Asn Glu 
    1070                 1075                 1080             


Gly Ile  Ser Ser Thr Val Ile  Thr Phe Met Thr Ser  Thr Ala Tyr 
    1085                 1090                 1095             


Thr Asn  Asn Gln Ala Asp Ile  Ala Thr Gln Gly Trp  Phe Ile Gly 
    1100                 1105                 1110             


Leu Met  Cys Ala Ile Ala Leu  Leu Val Leu Ile Leu  Leu Ile Val 
    1115                 1120                 1125             


Cys Phe  Ile Lys Arg Ser Arg  Gly Gly Lys Tyr Pro  Val Arg Glu 
    1130                 1135                 1140             


Lys Lys  Asp Val Pro Leu Gly  Pro Glu Asp Pro Lys  Glu Glu Asp 
    1145                 1150                 1155             


Gly Ser  Phe Asp Tyr Ser Asp  Glu Asp Asn Lys Pro  Leu Gln Gly 
    1160                 1165                 1170             


Ser Gln  Thr Ser Leu Asp Gly  Thr Ile Lys Gln Gln  Glu Ser Asp 
    1175                 1180                 1185             


Asp Ser  Leu Val Asp Tyr Gly  Glu Gly Gly Glu Gly  Gln Phe Asn 
    1190                 1195                 1200             


Glu Asp  Gly Ser Phe Ile Gly  Gln Tyr Thr Val Lys  Lys Asp Lys 
    1205                 1210                 1215             


Glu Glu  Thr Glu Gly Asn Glu  Ser Ser Glu Ala Thr  Ser Pro Val 
    1220                 1225                 1230             


Asn Ala  Ile Tyr Ser Leu Ala  
    1235                 1240 


<210>  2818
<211>  619
<212>  PRT
<213>  homo sapiens

<400>  2818

Met Leu Leu Ala Ser Ala Val Val Val Trp Glu Trp Leu Asn Glu His 
1               5                   10                  15      


Gly Arg Trp Arg Pro Tyr Ser Pro Ala Val Ser His His Ile Glu Ala 
            20                  25                  30          


Val Val Arg Ala Gly Pro Arg Ala Gly Gly Ser Val Val Leu Gly Gln 
        35                  40                  45              


Val Asp Ser Arg Leu Ala Pro Tyr Ile Ile Asp Leu Gln Ser Met Asn 
    50                  55                  60                  


Gln Phe Arg Gln Asp Thr Gly Thr Leu Arg Pro Val Arg Arg Asn Tyr 
65                  70                  75                  80  


Tyr Asp Pro Ser Ser Ala Pro Gly Lys Gly Val Val Trp Glu Trp Glu 
                85                  90                  95      


Asn Asp Asn Gly Ser Trp Thr Pro Tyr Asp Met Glu Val Gly Ile Thr 
            100                 105                 110         


Ile Gln His Ala Tyr Glu Lys Gln His Pro Trp Ile Asp Leu Thr Ser 
        115                 120                 125             


Ile Gly Phe Ser Tyr Val Ile Asp Phe Asn Thr Met Gly Gln Ile Asn 
    130                 135                 140                 


Arg Gln Thr Gln Arg Gln Arg Arg Val Arg Arg Arg Leu Asp Leu Ile 
145                 150                 155                 160 


Tyr Pro Met Val Thr Gly Thr Leu Pro Lys Ala Gln Ser Trp Pro Val 
                165                 170                 175     


Ser Pro Gly Pro Ala Thr Ser Pro Pro Met Ser Pro Cys Ser Cys Pro 
            180                 185                 190         


Gln Cys Val Leu Val Met Ser Val Lys Ala Ala Val Val Asn Gly Ser 
        195                 200                 205             


Thr Gly Pro Leu Gln Leu Pro Val Thr Arg Lys Asn Met Pro Pro Pro 
    210                 215                 220                 


Gly Val Val Lys Leu Pro Pro Leu Pro Gly Ser Gly Ala Lys Pro Leu 
225                 230                 235                 240 


Asp Ser Thr Gly Thr Ile Arg Gly Pro Leu Lys Thr Ala Pro Ser Gln 
                245                 250                 255     


Val Ile Arg Arg Gln Ala Ser Ser Met Pro Thr Gly Thr Thr Met Gly 
            260                 265                 270         


Ser Pro Ala Ser Pro Pro Gly Pro Asn Ser Lys Thr Gly Arg Val Ala 
        275                 280                 285             


Leu Ala Thr Leu Asn Arg Thr Asn Leu Gln Arg Leu Ala Ile Ala Gln 
    290                 295                 300                 


Ser Arg Val Leu Ile Ala Ser Gly Val Pro Thr Val Pro Val Lys Asn 
305                 310                 315                 320 


Leu Asn Gly Ser Ser Pro Val Asn Pro Ala Leu Ala Gly Ile Thr Gly 
                325                 330                 335     


Ile Leu Met Ser Ala Ala Gly Leu Pro Val Cys Leu Thr Arg Pro Pro 
            340                 345                 350         


Lys Leu Val Leu His Pro Pro Pro Val Ser Lys Ser Glu Ile Lys Ser 
        355                 360                 365             


Ile Pro Gly Val Ser Asn Thr Ser Arg Lys Thr Thr Lys Lys Gln Ala 
    370                 375                 380                 


Lys Lys Gly Lys Thr Pro Glu Glu Val Leu Lys Lys Tyr Leu Gln Lys 
385                 390                 395                 400 


Val Arg His Pro Pro Asp Glu Asp Cys Thr Ile Cys Met Glu Arg Leu 
                405                 410                 415     


Thr Ala Pro Ser Gly Tyr Lys Gly Pro Gln Pro Thr Val Lys Pro Asp 
            420                 425                 430         


Leu Val Gly Lys Leu Ser Arg Cys Gly His Val Tyr His Ile Tyr Cys 
        435                 440                 445             


Leu Val Ala Met Tyr Asn Asn Gly Asn Lys Asp Gly Ser Leu Gln Cys 
    450                 455                 460                 


Pro Thr Cys Lys Thr Ile Tyr Gly Val Lys Thr Gly Thr Gln Pro Pro 
465                 470                 475                 480 


Gly Lys Met Glu Tyr His Leu Ile Pro His Ser Leu Pro Gly His Pro 
                485                 490                 495     


Asp Cys Lys Thr Ile Arg Ile Ile Tyr Ser Ile Pro Pro Gly Ile Gln 
            500                 505                 510         


Gly Pro Glu His Pro Asn Pro Gly Lys Ser Phe Ser Ala Arg Gly Phe 
        515                 520                 525             


Pro Arg His Cys Tyr Leu Pro Asp Ser Glu Lys Gly Arg Lys Val Leu 
    530                 535                 540                 


Lys Leu Leu Leu Val Ala Trp Asp Arg Arg Leu Ile Phe Ala Ile Gly 
545                 550                 555                 560 


Thr Ser Ser Thr Thr Gly Glu Ser Asp Thr Val Ile Trp Asn Glu Val 
                565                 570                 575     


His His Lys Thr Glu Phe Gly Ser Asn Leu Thr Gly His Gly Tyr Pro 
            580                 585                 590         


Asp Ala Asn Tyr Leu Asp Asn Val Leu Ala Glu Leu Ala Ala Gln Gly 
        595                 600                 605             


Ile Ser Glu Asp Ser Thr Ala Gln Glu Lys Asp 
    610                 615                 


<210>  2819
<211>  434
<212>  PRT
<213>  homo sapiens

<400>  2819

Met Ala Ala Ala Ala Gly Ser Cys Ala Arg Val Ala Ala Trp Gly Gly 
1               5                   10                  15      


Lys Leu Arg Arg Gly Leu Ala Val Ser Arg Gln Ala Val Arg Ser Pro 
            20                  25                  30          


Gly Pro Leu Ala Ala Ala Val Ala Gly Ala Ala Leu Ala Gly Ala Gly 
        35                  40                  45              


Ala Ala Trp His His Ser Arg Val Ser Val Ala Ala Arg Asp Gly Ser 
    50                  55                  60                  


Phe Thr Val Ser Ala Gln Lys Asn Val Glu His Gly Ile Ile Tyr Ile 
65                  70                  75                  80  


Gly Lys Pro Ser Leu Arg Lys Gln Arg Phe Met Gln Phe Ser Ser Leu 
                85                  90                  95      


Glu His Glu Gly Glu Tyr Tyr Met Thr Pro Arg Asp Phe Leu Phe Ser 
            100                 105                 110         


Val Met Phe Glu Gln Met Glu Arg Lys Thr Ser Val Lys Lys Leu Thr 
        115                 120                 125             


Lys Lys Asp Ile Glu Asp Thr Leu Ser Gly Ile Gln Thr Ala Gly Cys 
    130                 135                 140                 


Gly Ser Thr Phe Phe Arg Asp Leu Gly Asp Lys Gly Leu Ile Ser Tyr 
145                 150                 155                 160 


Thr Glu Tyr Leu Phe Leu Leu Thr Ile Leu Thr Lys Pro His Ser Gly 
                165                 170                 175     


Phe His Val Ala Phe Lys Met Leu Asp Thr Asp Gly Asn Glu Met Ile 
            180                 185                 190         


Glu Lys Arg Glu Phe Phe Lys Leu Gln Lys Ile Ile Ser Lys Gln Asp 
        195                 200                 205             


Asp Leu Met Thr Val Lys Thr Asn Glu Thr Gly Tyr Gln Glu Ala Ile 
    210                 215                 220                 


Val Lys Glu Pro Glu Ile Asn Thr Thr Leu Gln Met Arg Phe Phe Gly 
225                 230                 235                 240 


Lys Arg Gly Gln Arg Lys Leu His Tyr Lys Glu Phe Arg Arg Phe Met 
                245                 250                 255     


Glu Asn Leu Gln Thr Glu Ile Gln Glu Met Glu Phe Leu Gln Phe Ser 
            260                 265                 270         


Lys Gly Leu Ser Phe Met Arg Lys Glu Asp Phe Ala Glu Trp Leu Leu 
        275                 280                 285             


Phe Phe Thr Asn Thr Glu Asn Lys Asp Ile Tyr Trp Lys Asn Val Arg 
    290                 295                 300                 


Glu Lys Leu Ser Ala Gly Glu Ser Ile Ser Leu Asp Glu Phe Lys Ser 
305                 310                 315                 320 


Phe Cys His Phe Thr Thr His Leu Glu Asp Phe Ala Ile Ala Met Gln 
                325                 330                 335     


Met Phe Ser Leu Ala His Arg Pro Val Arg Leu Ala Glu Phe Lys Arg 
            340                 345                 350         


Ala Val Lys Val Ala Thr Gly Gln Glu Leu Ser Asn Asn Ile Leu Asp 
        355                 360                 365             


Thr Val Phe Lys Ile Phe Asp Leu Asp Gly Asp Glu Cys Leu Ser His 
    370                 375                 380                 


Glu Glu Phe Leu Gly Val Leu Lys Asn Arg Met His Arg Gly Leu Trp 
385                 390                 395                 400 


Val Pro Gln His Gln Ser Ile Gln Glu Tyr Trp Lys Cys Val Lys Lys 
                405                 410                 415     


Glu Ser Ile Lys Gly Val Lys Glu Val Trp Lys Gln Ala Gly Lys Gly 
            420                 425                 430         


Leu Phe 
        


<210>  2820
<211>  2692
<212>  PRT
<213>  homo sapiens

<400>  2820

Met Met Asn Asn Ser Gly Tyr Ser Asp Ala Gly Leu Gly Leu Gly Asp 
1               5                   10                  15      


Glu Thr Asp Glu Met Pro Ser Thr Glu Lys Asp Leu Ala Glu Asp Ala 
            20                  25                  30          


Pro Trp Lys Lys Ile Gln Gln Asn Thr Phe Thr Arg Trp Cys Asn Glu 
        35                  40                  45              


His Leu Lys Cys Val Gly Lys Arg Leu Thr Asp Leu Gln Arg Asp Leu 
    50                  55                  60                  


Ser Asp Gly Leu Arg Leu Ile Ala Leu Leu Glu Val Leu Ser Gln Lys 
65                  70                  75                  80  


Arg Met Tyr Arg Lys Phe His Pro Arg Pro Asn Phe Arg Gln Met Lys 
                85                  90                  95      


Leu Glu Asn Val Ser Val Ala Leu Glu Phe Leu Glu Arg Glu His Ile 
            100                 105                 110         


Lys Leu Val Ser Ile Asp Ser Lys Ala Ile Val Asp Gly Asn Leu Lys 
        115                 120                 125             


Leu Ile Leu Gly Leu Ile Trp Thr Leu Ile Leu His Tyr Ser Ile Ser 
    130                 135                 140                 


Met Pro Met Trp Glu Asp Glu Asp Asp Glu Asp Ala Arg Lys Gln Thr 
145                 150                 155                 160 


Pro Lys Gln Arg Leu Leu Gly Trp Ile Gln Asn Lys Val Pro Gln Leu 
                165                 170                 175     


Pro Ile Thr Asn Phe Asn Arg Asp Trp Gln Asp Gly Lys Ala Leu Gly 
            180                 185                 190         


Ala Leu Val Asp Asn Cys Ala Pro Gly Leu Cys Pro Asp Trp Glu Ala 
        195                 200                 205             


Trp Asp Pro Asn Gln Pro Val Glu Asn Ala Arg Glu Ala Met Gln Gln 
    210                 215                 220                 


Ala Asp Asp Trp Leu Gly Val Pro Gln Val Ile Ala Pro Glu Glu Ile 
225                 230                 235                 240 


Val Asp Pro Asn Val Asp Glu His Ser Val Met Thr Tyr Leu Ser Gln 
                245                 250                 255     


Phe Pro Lys Ala Lys Leu Lys Pro Gly Ala Pro Val Arg Ser Lys Gln 
            260                 265                 270         


Leu Asn Pro Lys Lys Ala Ile Ala Tyr Gly Pro Gly Ile Glu Pro Gln 
        275                 280                 285             


Gly Asn Thr Val Leu Gln Pro Ala His Phe Thr Val Gln Thr Val Asp 
    290                 295                 300                 


Ala Gly Val Gly Glu Val Leu Val Tyr Ile Glu Asp Pro Glu Gly His 
305                 310                 315                 320 


Thr Glu Glu Ala Lys Val Val Pro Asn Asn Asp Lys Asp Arg Thr Tyr 
                325                 330                 335     


Ala Val Ser Tyr Val Pro Lys Val Ala Gly Leu His Lys Val Thr Val 
            340                 345                 350         


Leu Phe Ala Gly Gln Asn Ile Glu Arg Ser Pro Phe Glu Val Asn Val 
        355                 360                 365             


Gly Met Ala Leu Gly Asp Ala Asn Lys Val Ser Ala Arg Gly Pro Gly 
    370                 375                 380                 


Leu Glu Pro Val Gly Asn Val Ala Asn Lys Pro Thr Tyr Phe Asp Ile 
385                 390                 395                 400 


Tyr Thr Ala Gly Ala Gly Thr Gly Asp Val Ala Val Val Ile Val Asp 
                405                 410                 415     


Pro Gln Gly Arg Arg Asp Thr Val Glu Val Ala Leu Glu Asp Lys Gly 
            420                 425                 430         


Asp Ser Thr Phe Arg Cys Thr Tyr Arg Pro Ala Met Glu Gly Pro His 
        435                 440                 445             


Thr Val His Val Ala Phe Ala Gly Ala Pro Ile Thr Arg Ser Pro Phe 
    450                 455                 460                 


Pro Val His Val Ser Glu Ala Cys Asn Pro Asn Ala Cys Arg Ala Ser 
465                 470                 475                 480 


Gly Arg Gly Leu Gln Pro Lys Gly Val Arg Val Lys Glu Val Ala Asp 
                485                 490                 495     


Phe Lys Val Phe Thr Lys Gly Ala Gly Ser Gly Glu Leu Lys Val Thr 
            500                 505                 510         


Val Lys Gly Pro Lys Gly Thr Glu Glu Pro Val Lys Val Arg Glu Ala 
        515                 520                 525             


Gly Asp Gly Val Phe Glu Cys Glu Tyr Tyr Pro Val Val Pro Gly Lys 
    530                 535                 540                 


Tyr Val Val Thr Ile Thr Trp Gly Gly Tyr Ala Ile Pro Arg Ser Pro 
545                 550                 555                 560 


Phe Glu Val Gln Val Ser Pro Glu Ala Gly Val Gln Lys Val Arg Ala 
                565                 570                 575     


Trp Gly Pro Gly Leu Glu Thr Gly Gln Val Gly Lys Ser Ala Asp Phe 
            580                 585                 590         


Val Val Glu Ala Ile Gly Thr Glu Val Gly Thr Leu Gly Phe Ser Ile 
        595                 600                 605             


Glu Gly Pro Ser Gln Ala Lys Ile Glu Cys Asp Asp Lys Gly Asp Gly 
    610                 615                 620                 


Ser Cys Asp Val Arg Tyr Trp Pro Thr Glu Pro Gly Glu Tyr Ala Val 
625                 630                 635                 640 


His Val Ile Cys Asp Asp Glu Asp Ile Arg Asp Ser Pro Phe Ile Ala 
                645                 650                 655     


His Ile Leu Pro Ala Pro Pro Asp Cys Phe Pro Asp Lys Val Lys Ala 
            660                 665                 670         


Phe Gly Pro Gly Leu Glu Pro Thr Gly Cys Ile Val Asp Lys Pro Ala 
        675                 680                 685             


Glu Phe Thr Ile Asp Ala Arg Ala Ala Gly Lys Gly Asp Leu Lys Leu 
    690                 695                 700                 


Tyr Ala Gln Asp Ala Asp Gly Cys Pro Ile Asp Ile Lys Val Ile Pro 
705                 710                 715                 720 


Asn Gly Asp Gly Thr Phe Arg Cys Ser Tyr Val Pro Thr Lys Pro Ile 
                725                 730                 735     


Lys His Thr Ile Ile Ile Ser Trp Gly Gly Val Asn Val Pro Lys Ser 
            740                 745                 750         


Pro Phe Arg Val Asn Val Gly Glu Gly Ser His Pro Glu Arg Val Lys 
        755                 760                 765             


Val Tyr Gly Pro Gly Val Glu Lys Thr Gly Leu Lys Ala Asn Glu Pro 
    770                 775                 780                 


Thr Tyr Phe Thr Val Asp Cys Ser Glu Ala Gly Gln Gly Asp Val Ser 
785                 790                 795                 800 


Ile Gly Ile Lys Cys Ala Pro Gly Val Val Gly Pro Ala Glu Ala Asp 
                805                 810                 815     


Ile Asp Phe Asp Ile Ile Lys Asn Asp Asn Asp Thr Phe Thr Val Lys 
            820                 825                 830         


Tyr Thr Pro Pro Gly Ala Gly Arg Tyr Thr Ile Met Val Leu Phe Ala 
        835                 840                 845             


Asn Gln Glu Ile Pro Ala Ser Pro Phe His Ile Lys Val Asp Pro Ser 
    850                 855                 860                 


His Asp Ala Ser Lys Val Lys Ala Glu Gly Pro Gly Leu Asn Arg Thr 
865                 870                 875                 880 


Gly Val Glu Val Gly Lys Pro Thr His Phe Thr Val Leu Thr Lys Gly 
                885                 890                 895     


Ala Gly Lys Ala Lys Leu Asp Val Gln Phe Ala Gly Thr Ala Lys Gly 
            900                 905                 910         


Glu Val Val Arg Asp Phe Glu Ile Ile Asp Asn His Asp Tyr Ser Tyr 
        915                 920                 925             


Thr Val Lys Tyr Thr Ala Val Gln Gln Gly Asn Met Ala Val Thr Val 
    930                 935                 940                 


Thr Tyr Gly Gly Asp Pro Val Pro Lys Ser Pro Phe Val Val Asn Val 
945                 950                 955                 960 


Ala Pro Pro Leu Asp Leu Ser Lys Ile Lys Val Gln Gly Leu Asn Ser 
                965                 970                 975     


Lys Val Ala Val Gly Gln Glu Gln Ala Phe Ser Val Asn Thr Arg Gly 
            980                 985                 990         


Ala Gly Gly Gln Gly Gln Leu Asp  Val Arg Met Thr Ser  Pro Ser Arg 
        995                 1000                 1005             


Arg Pro  Ile Pro Cys Lys Leu  Glu Pro Gly Gly Gly  Ala Glu Ala 
    1010                 1015                 1020             


Gln Ala  Val Arg Tyr Met Pro  Pro Glu Glu Gly Pro  Tyr Lys Val 
    1025                 1030                 1035             


Asp Ile  Thr Tyr Asp Gly His  Pro Val Pro Gly Ser  Pro Phe Ala 
    1040                 1045                 1050             


Val Glu  Gly Val Leu Pro Pro  Asp Pro Ser Lys Val  Cys Ala Tyr 
    1055                 1060                 1065             


Gly Pro  Gly Leu Lys Gly Gly  Leu Val Gly Thr Pro  Ala Pro Phe 
    1070                 1075                 1080             


Ser Ile  Asp Thr Lys Gly Ala  Gly Thr Gly Gly Leu  Gly Leu Thr 
    1085                 1090                 1095             


Val Glu  Gly Pro Cys Glu Ala  Lys Ile Glu Cys Gln  Asp Asn Gly 
    1100                 1105                 1110             


Asp Gly  Ser Cys Ala Val Ser  Tyr Leu Pro Thr Glu  Pro Gly Glu 
    1115                 1120                 1125             


Tyr Thr  Ile Asn Ile Leu Phe  Ala Glu Ala His Ile  Pro Gly Ser 
    1130                 1135                 1140             


Pro Phe  Lys Ala Thr Ile Arg  Pro Val Phe Asp Pro  Ser Lys Val 
    1145                 1150                 1155             


Arg Ala  Ser Gly Pro Gly Leu  Glu Arg Gly Lys Val  Gly Glu Ala 
    1160                 1165                 1170             


Ala Thr  Phe Thr Val Asp Cys  Ser Glu Ala Gly Glu  Ala Glu Leu 
    1175                 1180                 1185             


Thr Ile  Glu Ile Leu Ser Asp  Ala Gly Val Lys Ala  Glu Val Leu 
    1190                 1195                 1200             


Ile His  Asn Asn Ala Asp Gly  Thr Tyr His Ile Thr  Tyr Ser Pro 
    1205                 1210                 1215             


Ala Phe  Pro Gly Thr Tyr Thr  Ile Thr Ile Lys Tyr  Gly Gly His 
    1220                 1225                 1230             


Pro Val  Pro Lys Phe Pro Thr  Arg Val His Val Gln  Pro Ala Val 
    1235                 1240                 1245             


Asp Thr  Ser Gly Val Lys Val  Ser Gly Pro Gly Val  Glu Pro His 
    1250                 1255                 1260             


Gly Val  Leu Arg Glu Val Thr  Thr Glu Phe Thr Val  Asp Ala Arg 
    1265                 1270                 1275             


Ser Leu  Thr Ala Thr Gly Gly  Asn His Val Thr Ala  Arg Val Leu 
    1280                 1285                 1290             


Asn Pro  Ser Gly Ala Lys Thr  Asp Thr Tyr Val Thr  Asp Asn Gly 
    1295                 1300                 1305             


Asp Gly  Thr Tyr Arg Val Gln  Tyr Thr Ala Tyr Glu  Glu Gly Val 
    1310                 1315                 1320             


His Leu  Val Glu Val Leu Tyr  Asp Glu Val Ala Val  Pro Lys Ser 
    1325                 1330                 1335             


Pro Phe  Arg Val Gly Val Thr  Glu Gly Cys Asp Pro  Thr Arg Val 
    1340                 1345                 1350             


Arg Ala  Phe Gly Pro Gly Leu  Glu Gly Gly Leu Val  Asn Lys Ala 
    1355                 1360                 1365             


Asn Arg  Phe Thr Val Glu Thr  Arg Gly Ala Gly Thr  Gly Gly Leu 
    1370                 1375                 1380             


Gly Leu  Ala Ile Glu Gly Pro  Ser Glu Ala Lys Met  Ser Cys Lys 
    1385                 1390                 1395             


Asp Asn  Lys Asp Gly Ser Cys  Thr Val Glu Tyr Ile  Pro Phe Thr 
    1400                 1405                 1410             


Pro Gly  Asp Tyr Asp Val Asn  Ile Thr Phe Gly Gly  Arg Pro Ile 
    1415                 1420                 1425             


Pro Gly  Ser Pro Phe Arg Val  Pro Val Lys Asp Val  Val Asp Pro 
    1430                 1435                 1440             


Gly Lys  Val Lys Cys Ser Gly  Pro Gly Leu Gly Ala  Gly Val Arg 
    1445                 1450                 1455             


Ala Arg  Val Pro Gln Thr Phe  Thr Val Asp Cys Ser  Gln Ala Gly 
    1460                 1465                 1470             


Arg Ala  Pro Leu Gln Val Ala  Val Leu Gly Pro Thr  Gly Val Ala 
    1475                 1480                 1485             


Glu Pro  Val Glu Val Arg Asp  Asn Gly Asp Gly Thr  His Thr Val 
    1490                 1495                 1500             


His Tyr  Thr Pro Ala Thr Asp  Gly Pro Tyr Thr Val  Ala Val Lys 
    1505                 1510                 1515             


Tyr Ala  Asp Gln Glu Val Pro  Arg Ser Pro Phe Lys  Ile Lys Val 
    1520                 1525                 1530             


Leu Pro  Ala His Asp Ala Ser  Lys Val Arg Ala Ser  Gly Pro Gly 
    1535                 1540                 1545             


Leu Asn  Ala Ser Gly Ile Pro  Ala Ser Leu Pro Val  Glu Phe Thr 
    1550                 1555                 1560             


Ile Asp  Ala Arg Asp Ala Gly  Glu Gly Leu Leu Thr  Val Gln Ile 
    1565                 1570                 1575             


Leu Asp  Pro Glu Gly Lys Pro  Lys Lys Ala Asn Ile  Arg Asp Asn 
    1580                 1585                 1590             


Gly Asp  Gly Thr Tyr Thr Val  Ser Tyr Leu Pro Asp  Met Ser Gly 
    1595                 1600                 1605             


Arg Tyr  Thr Ile Thr Ile Lys  Tyr Gly Gly Asp Glu  Ile Pro Tyr 
    1610                 1615                 1620             


Ser Pro  Phe Arg Ile His Ala  Leu Pro Thr Gly Asp  Ala Ser Lys 
    1625                 1630                 1635             


Cys Leu  Val Thr Val Ser Ile  Gly Gly His Gly Leu  Gly Ala Cys 
    1640                 1645                 1650             


Leu Gly  Pro Arg Ile Gln Ile  Gly Gln Glu Thr Val  Ile Thr Val 
    1655                 1660                 1665             


Asp Ala  Lys Ala Ala Gly Glu  Gly Lys Val Thr Cys  Thr Val Ser 
    1670                 1675                 1680             


Thr Pro  Asp Gly Ala Glu Leu  Asp Val Asp Val Val  Glu Asn His 
    1685                 1690                 1695             


Asp Gly  Thr Phe Asp Ile Tyr  Tyr Thr Ala Pro Glu  Pro Gly Lys 
    1700                 1705                 1710             


Tyr Val  Ile Thr Ile Arg Phe  Gly Gly Glu His Ile  Pro Asn Ser 
    1715                 1720                 1725             


Pro Phe  His Val Leu Ala Thr  Glu Glu Pro Val Val  Pro Val Glu 
    1730                 1735                 1740             


Pro Met  Glu Ser Met Leu Arg  Pro Phe Asn Leu Val  Ile Pro Phe 
    1745                 1750                 1755             


Ala Val  Gln Lys Gly Glu Leu  Thr Gly Glu Val Arg  Met Pro Ser 
    1760                 1765                 1770             


Gly Lys  Thr Ala Arg Pro Asn  Ile Thr Asp Asn Lys  Asp Gly Thr 
    1775                 1780                 1785             


Ile Thr  Val Arg Tyr Ala Pro  Thr Glu Lys Gly Leu  His Gln Met 
    1790                 1795                 1800             


Gly Ile  Lys Tyr Asp Gly Asn  His Ile Pro Gly Ser  Pro Leu Gln 
    1805                 1810                 1815             


Phe Tyr  Val Asp Ala Ile Asn  Ser Arg His Val Ser  Ala Tyr Gly 
    1820                 1825                 1830             


Pro Gly  Leu Ser His Gly Met  Val Asn Lys Pro Ala  Thr Phe Thr 
    1835                 1840                 1845             


Ile Val  Thr Lys Asp Ala Gly  Glu Gly Gly Leu Ser  Leu Ala Val 
    1850                 1855                 1860             


Glu Gly  Pro Ser Lys Ala Glu  Ile Thr Cys Lys Asp  Asn Lys Asp 
    1865                 1870                 1875             


Gly Thr  Cys Thr Val Ser Tyr  Leu Pro Thr Ala Pro  Gly Asp Tyr 
    1880                 1885                 1890             


Ser Ile  Ile Val Arg Phe Asp  Asp Lys His Ile Pro  Gly Ser Pro 
    1895                 1900                 1905             


Phe Thr  Ala Lys Ile Thr Gly  Asp Asp Ser Met Arg  Thr Ser Gln 
    1910                 1915                 1920             


Leu Asn  Val Gly Thr Ser Thr  Asp Val Ser Leu Lys  Ile Thr Glu 
    1925                 1930                 1935             


Ser Asp  Leu Ser Gln Leu Thr  Ala Ser Ile Arg Ala  Pro Ser Gly 
    1940                 1945                 1950             


Asn Glu  Glu Pro Cys Leu Leu  Lys Arg Leu Pro Asn  Arg His Ile 
    1955                 1960                 1965             


Gly Ile  Ser Phe Thr Pro Lys  Glu Val Gly Glu His  Val Val Ser 
    1970                 1975                 1980             


Val Arg  Lys Ser Gly Lys His  Val Thr Asn Ser Pro  Phe Lys Ile 
    1985                 1990                 1995             


Leu Val  Gly Pro Ser Glu Ile  Gly Asp Ala Ser Lys  Val Arg Val 
    2000                 2005                 2010             


Trp Gly  Lys Gly Leu Ser Glu  Gly His Thr Phe Gln  Val Ala Glu 
    2015                 2020                 2025             


Phe Ile  Val Asp Thr Arg Asn  Ala Gly Tyr Gly Gly  Leu Gly Leu 
    2030                 2035                 2040             


Ser Ile  Glu Gly Pro Ser Lys  Val Asp Ile Asn Cys  Glu Asp Met 
    2045                 2050                 2055             


Glu Asp  Gly Thr Cys Lys Val  Thr Tyr Cys Pro Thr  Glu Pro Gly 
    2060                 2065                 2070             


Thr Tyr  Ile Ile Asn Ile Lys  Phe Ala Asp Lys His  Val Pro Gly 
    2075                 2080                 2085             


Ser Pro  Phe Thr Val Lys Val  Thr Gly Glu Gly Arg  Met Lys Glu 
    2090                 2095                 2100             


Ser Ile  Thr Arg Arg Arg Gln  Ala Pro Ser Ile Ala  Thr Ile Gly 
    2105                 2110                 2115             


Ser Thr  Cys Asp Leu Asn Leu  Lys Ile Pro Gly Asn  Trp Phe Gln 
    2120                 2125                 2130             


Met Val  Ser Ala Gln Glu Arg  Leu Thr Arg Thr Phe  Thr Arg Ser 
    2135                 2140                 2145             


Ser His  Thr Tyr Thr Arg Thr  Glu Arg Thr Glu Ile  Ser Lys Thr 
    2150                 2155                 2160             


Arg Gly  Gly Glu Thr Lys Arg  Glu Val Arg Val Glu  Glu Ser Thr 
    2165                 2170                 2175             


Gln Val  Gly Gly Asp Pro Phe  Pro Ala Val Phe Gly  Asp Phe Leu 
    2180                 2185                 2190             


Gly Arg  Glu Arg Leu Gly Ser  Phe Gly Ser Ile Thr  Arg Gln Gln 
    2195                 2200                 2205             


Glu Gly  Glu Ala Ser Ser Gln  Asp Met Thr Ala Gln  Val Thr Ser 
    2210                 2215                 2220             


Pro Ser  Gly Lys Val Glu Ala  Ala Glu Ile Val Glu  Gly Glu Asp 
    2225                 2230                 2235             


Ser Ala  Tyr Ser Val Arg Phe  Val Pro Gln Glu Met  Gly Pro His 
    2240                 2245                 2250             


Thr Val  Ala Val Lys Tyr Arg  Gly Gln His Val Pro  Gly Ser Pro 
    2255                 2260                 2265             


Phe Gln  Phe Thr Val Gly Pro  Leu Gly Glu Gly Gly  Ala His Lys 
    2270                 2275                 2280             


Val Arg  Ala Gly Gly Thr Gly  Leu Glu Arg Gly Val  Ala Gly Val 
    2285                 2290                 2295             


Pro Ala  Glu Phe Ser Ile Trp  Thr Arg Glu Ala Gly  Ala Gly Gly 
    2300                 2305                 2310             


Leu Ser  Ile Ala Val Glu Gly  Pro Ser Lys Ala Glu  Ile Ala Phe 
    2315                 2320                 2325             


Glu Asp  Arg Lys Asp Gly Ser  Cys Gly Val Ser Tyr  Val Val Gln 
    2330                 2335                 2340             


Glu Pro  Gly Asp Tyr Glu Val  Ser Ile Lys Phe Asn  Asp Glu His 
    2345                 2350                 2355             


Ile Pro  Asp Ser Pro Phe Val  Val Pro Val Ala Ser  Leu Ser Asp 
    2360                 2365                 2370             


Asp Ala  Arg Arg Leu Thr Val  Thr Ser Leu Gln Glu  Thr Gly Leu 
    2375                 2380                 2385             


Lys Val  Asn Gln Pro Ala Ser  Phe Ala Val Gln Leu  Asn Gly Ala 
    2390                 2395                 2400             


Arg Gly  Val Ile Asp Ala Arg  Val His Thr Pro Ser  Gly Ala Val 
    2405                 2410                 2415             


Glu Glu  Cys Tyr Val Ser Glu  Leu Asp Ser Asp Lys  His Thr Ile 
    2420                 2425                 2430             


Arg Phe  Ile Pro His Glu Asn  Gly Val His Ser Ile  Asp Val Lys 
    2435                 2440                 2445             


Phe Asn  Gly Ala His Ile Pro  Gly Ser Pro Phe Lys  Ile Arg Val 
    2450                 2455                 2460             


Gly Glu  Gln Ser Gln Ala Gly  Asp Pro Gly Leu Val  Ser Ala Tyr 
    2465                 2470                 2475             


Gly Pro  Gly Leu Glu Gly Gly  Thr Thr Gly Val Ser  Ser Glu Phe 
    2480                 2485                 2490             


Ile Val  Asn Thr Leu Asn Ala  Gly Ser Gly Ala Leu  Ser Val Thr 
    2495                 2500                 2505             


Ile Asp  Gly Pro Ser Lys Val  Gln Leu Asp Cys Arg  Glu Cys Pro 
    2510                 2515                 2520             


Glu Gly  His Val Val Thr Tyr  Thr Pro Met Ala Pro  Gly Asn Tyr 
    2525                 2530                 2535             


Leu Ile  Ala Ile Lys Tyr Gly  Gly Pro Gln His Ile  Val Gly Ser 
    2540                 2545                 2550             


Pro Phe  Lys Ala Lys Val Thr  Gly Pro Arg Leu Ser  Gly Gly His 
    2555                 2560                 2565             


Ser Leu  His Glu Thr Ser Thr  Val Leu Val Glu Thr  Val Thr Lys 
    2570                 2575                 2580             


Ser Ser  Ser Ser Arg Gly Ser  Ser Tyr Ser Ser Ile  Pro Lys Phe 
    2585                 2590                 2595             


Ser Ser  Asp Ala Ser Lys Val  Val Thr Arg Gly Pro  Gly Leu Ser 
    2600                 2605                 2610             


Gln Ala  Phe Val Gly Gln Lys  Asn Ser Phe Thr Val  Asp Cys Ser 
    2615                 2620                 2625             


Lys Ala  Gly Thr Asn Met Met  Met Val Gly Val His  Gly Pro Lys 
    2630                 2635                 2640             


Thr Pro  Cys Glu Glu Val Tyr  Val Lys His Met Gly  Asn Arg Val 
    2645                 2650                 2655             


Tyr Asn  Val Thr Tyr Thr Val  Lys Glu Lys Gly Asp  Tyr Ile Leu 
    2660                 2665                 2670             


Ile Val  Lys Trp Gly Asp Glu  Ser Val Pro Gly Ser  Pro Phe Lys 
    2675                 2680                 2685             


Val Lys  Val Pro 
    2690         


<210>  2821
<211>  558
<212>  PRT
<213>  homo sapiens

<400>  2821

Met Ala Val Pro Ala Ala Leu Ile Pro Pro Thr Gln Leu Val Pro Pro 
1               5                   10                  15      


Gln Pro Pro Ile Ser Thr Ser Ala Ser Ser Ser Gly Thr Thr Thr Ser 
            20                  25                  30          


Thr Ser Ser Ala Thr Ser Ser Pro Ala Pro Ser Ile Gly Pro Pro Ala 
        35                  40                  45              


Ser Ser Gly Pro Thr Leu Phe Arg Pro Glu Pro Ile Ala Ser Ala Ala 
    50                  55                  60                  


Ala Ala Ala Ala Thr Val Thr Ser Thr Gly Gly Gly Gly Gly Gly Gly 
65                  70                  75                  80  


Gly Ser Gly Gly Gly Gly Gly Ser Ser Gly Asn Gly Gly Gly Gly Gly 
                85                  90                  95      


Gly Gly Gly Gly Gly Ser Asn Cys Asn Pro Asn Leu Ala Ala Ala Ser 
            100                 105                 110         


Asn Gly Ser Gly Gly Gly Gly Gly Gly Ile Ser Ala Gly Gly Gly Val 
        115                 120                 125             


Ala Ser Ser Thr Pro Ile Asn Ala Ser Thr Gly Ser Ser Ser Ser Ser 
    130                 135                 140                 


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser 
145                 150                 155                 160 


Ser Ser Ser Cys Gly Pro Leu Pro Gly Lys Pro Val Tyr Ser Thr Pro 
                165                 170                 175     


Ser Pro Val Glu Asn Thr Pro Gln Asn Asn Glu Cys Lys Met Val Asp 
            180                 185                 190         


Leu Arg Gly Ala Lys Val Ala Ser Phe Thr Val Glu Gly Cys Glu Leu 
        195                 200                 205             


Ile Cys Leu Pro Gln Ala Phe Asp Leu Phe Leu Lys His Leu Val Gly 
    210                 215                 220                 


Gly Leu His Thr Val Tyr Thr Lys Leu Lys Arg Leu Glu Ile Thr Pro 
225                 230                 235                 240 


Val Val Cys Asn Val Glu Gln Val Arg Ile Leu Arg Gly Leu Gly Ala 
                245                 250                 255     


Ile Gln Pro Gly Val Asn Arg Cys Lys Leu Ile Ser Arg Lys Asp Phe 
            260                 265                 270         


Glu Thr Leu Tyr Asn Asp Cys Thr Asn Ala Ser Ser Arg Pro Gly Arg 
        275                 280                 285             


Pro Pro Lys Arg Thr Gln Ser Val Thr Ser Pro Glu Asn Ser His Ile 
    290                 295                 300                 


Met Pro His Ser Val Pro Gly Leu Met Ser Pro Gly Ile Ile Pro Pro 
305                 310                 315                 320 


Thr Gly Leu Thr Ala Ala Ala Ala Ala Ala Ala Ala Ala Thr Asn Ala 
                325                 330                 335     


Ala Ile Ala Glu Ala Met Lys Val Lys Lys Ile Lys Leu Glu Ala Met 
            340                 345                 350         


Ser Asn Tyr His Ala Ser Asn Asn Gln His Gly Ala Asp Ser Glu Asn 
        355                 360                 365             


Gly Asp Met Asn Ser Ser Val Asp Glu Thr Pro Leu Ser Thr Pro Thr 
    370                 375                 380                 


Ala Arg Asp Ser Leu Asp Lys Leu Ser Leu Thr Gly His Gly Gln Pro 
385                 390                 395                 400 


Leu Pro Pro Gly Phe Pro Ser Pro Phe Leu Phe Pro Asp Gly Leu Ser 
                405                 410                 415     


Ser Ile Glu Thr Leu Leu Thr Asn Ile Gln Gly Leu Leu Lys Val Ala 
            420                 425                 430         


Ile Asp Asn Ala Arg Ala Gln Glu Lys Gln Val Gln Leu Glu Lys Thr 
        435                 440                 445             


Glu Leu Lys Met Asp Phe Leu Arg Glu Arg Glu Leu Arg Glu Thr Leu 
    450                 455                 460                 


Glu Lys Gln Leu Ala Met Glu Gln Lys Asn Arg Ala Ile Val Gln Lys 
465                 470                 475                 480 


Arg Leu Lys Lys Glu Lys Lys Ala Lys Arg Lys Leu Gln Glu Ala Leu 
                485                 490                 495     


Glu Phe Glu Thr Lys Arg Arg Glu Gln Ala Glu Gln Thr Leu Lys Gln 
            500                 505                 510         


Ala Ala Ser Thr Asp Ser Leu Arg Val Leu Asn Asp Ser Leu Thr Pro 
        515                 520                 525             


Glu Ile Glu Ala Asp Arg Ser Gly Gly Arg Thr Asp Ala Glu Arg Thr 
    530                 535                 540                 


Ile Gln Asp Gly Arg Leu Tyr Leu Lys Thr Thr Val Met Tyr 
545                 550                 555             


<210>  2822
<211>  236
<212>  PRT
<213>  homo sapiens

<400>  2822

Met Ala Ala Phe Ser Lys Tyr Leu Thr Ala Arg Asn Ser Ser Leu Ala 
1               5                   10                  15      


Gly Ala Ala Phe Leu Leu Leu Cys Leu Leu His Lys Arg Arg Arg Ala 
            20                  25                  30          


Leu Gly Leu His Gly Lys Lys Ser Gly Lys Pro Pro Leu Gln Asn Asn 
        35                  40                  45              


Glu Lys Glu Gly Lys Lys Glu Arg Ala Val Val Asp Lys Val Phe Phe 
    50                  55                  60                  


Ser Arg Leu Ile Gln Ile Leu Lys Ile Met Val Pro Arg Thr Phe Cys 
65                  70                  75                  80  


Lys Glu Thr Gly Tyr Leu Val Leu Ile Ala Val Met Leu Val Ser Arg 
                85                  90                  95      


Thr Tyr Cys Asp Val Trp Met Ile Gln Asn Gly Thr Leu Ile Glu Ser 
            100                 105                 110         


Gly Ile Ile Gly Arg Ser Arg Lys Asp Phe Lys Arg Tyr Leu Leu Asn 
        115                 120                 125             


Phe Ile Ala Ala Met Pro Leu Ile Ser Leu Val Asn Asn Phe Leu Lys 
    130                 135                 140                 


Tyr Gly Leu Asn Glu Leu Lys Leu Cys Phe Arg Val Arg Leu Thr Lys 
145                 150                 155                 160 


Tyr Leu Tyr Glu Glu Tyr Leu Gln Ala Phe Thr Tyr Tyr Lys Met Gly 
                165                 170                 175     


Asn Leu Asp Asn Arg Ile Ala Asn Pro Asp Gln Leu Leu Thr Gln Asp 
            180                 185                 190         


Val Glu Lys Phe Cys Asn Ser Val Val Asp Leu Tyr Ser Asn Leu Ser 
        195                 200                 205             


Lys Pro Phe Leu Asp Ile Val Leu Tyr Ile Phe Lys Leu Thr Ser Ala 
    210                 215                 220                 


Ile Gly Ala Gln Val Leu Gly Lys Ile Leu Trp His 
225                 230                 235     


<210>  2823
<211>  821
<212>  PRT
<213>  homo sapiens

<400>  2823

Met Asp Leu Ala Ala Ala Ala Glu Pro Gly Ala Gly Ser Gln His Leu 
1               5                   10                  15      


Glu Val Arg Asp Glu Val Ala Glu Lys Cys Gln Lys Leu Phe Leu Asp 
            20                  25                  30          


Phe Leu Glu Glu Phe Gln Ser Ser Asp Gly Glu Ile Lys Tyr Leu Gln 
        35                  40                  45              


Leu Ala Glu Glu Leu Ile Arg Pro Glu Arg Asn Thr Leu Val Val Ser 
    50                  55                  60                  


Phe Val Asp Leu Glu Gln Phe Asn Gln Gln Leu Ser Thr Thr Ile Gln 
65                  70                  75                  80  


Glu Glu Phe Tyr Arg Val Tyr Pro Tyr Leu Cys Arg Ala Leu Lys Thr 
                85                  90                  95      


Phe Val Lys Asp Arg Lys Glu Ile Pro Leu Ala Lys Asp Phe Tyr Val 
            100                 105                 110         


Ala Phe Gln Asp Leu Pro Thr Arg His Lys Ile Arg Glu Leu Thr Ser 
        115                 120                 125             


Ser Arg Ile Gly Leu Leu Thr Arg Ile Ser Gly Gln Val Val Arg Thr 
    130                 135                 140                 


His Pro Val His Pro Glu Leu Val Ser Gly Thr Phe Leu Cys Leu Asp 
145                 150                 155                 160 


Cys Gln Thr Val Ile Arg Asp Val Glu Gln Gln Phe Lys Tyr Thr Gln 
                165                 170                 175     


Pro Asn Ile Cys Arg Asn Pro Val Cys Ala Asn Arg Arg Arg Phe Leu 
            180                 185                 190         


Leu Asp Thr Asn Lys Ser Arg Phe Val Asp Phe Gln Lys Val Arg Ile 
        195                 200                 205             


Gln Glu Thr Gln Ala Glu Leu Pro Arg Gly Ser Ile Pro Arg Ser Leu 
    210                 215                 220                 


Glu Val Ile Leu Arg Ala Glu Ala Val Glu Ser Ala Gln Ala Gly Asp 
225                 230                 235                 240 


Lys Cys Asp Phe Thr Gly Thr Leu Ile Val Val Pro Asp Val Ser Lys 
                245                 250                 255     


Leu Ser Thr Pro Gly Ala Arg Ala Glu Thr Asn Ser Arg Val Ser Gly 
            260                 265                 270         


Val Asp Gly Tyr Glu Thr Glu Gly Ile Arg Gly Leu Arg Ala Leu Gly 
        275                 280                 285             


Val Arg Asp Leu Ser Tyr Arg Leu Val Phe Leu Ala Cys Cys Val Ala 
    290                 295                 300                 


Pro Thr Asn Pro Arg Phe Gly Gly Lys Glu Leu Arg Asp Glu Glu Gln 
305                 310                 315                 320 


Thr Ala Glu Ser Ile Lys Asn Gln Met Thr Val Lys Glu Trp Glu Lys 
                325                 330                 335     


Val Phe Glu Met Ser Gln Asp Lys Asn Leu Tyr His Asn Leu Cys Thr 
            340                 345                 350         


Ser Leu Phe Pro Thr Ile His Gly Asn Asp Glu Val Lys Arg Gly Val 
        355                 360                 365             


Leu Leu Met Leu Phe Gly Gly Val Pro Lys Thr Thr Gly Glu Gly Thr 
    370                 375                 380                 


Ser Leu Arg Gly Asp Ile Asn Val Cys Ile Val Gly Asp Pro Ser Thr 
385                 390                 395                 400 


Ala Lys Ser Gln Phe Leu Lys His Val Glu Glu Phe Ser Pro Arg Ala 
                405                 410                 415     


Val Tyr Thr Ser Gly Lys Ala Ser Ser Ala Ala Gly Leu Thr Ala Ala 
            420                 425                 430         


Val Val Arg Asp Glu Glu Ser His Glu Phe Val Ile Glu Ala Gly Ala 
        435                 440                 445             


Leu Met Leu Ala Asp Asn Gly Val Cys Cys Ile Asp Glu Phe Asp Lys 
    450                 455                 460                 


Met Asp Val Arg Asp Gln Val Ala Ile His Glu Ala Met Glu Gln Gln 
465                 470                 475                 480 


Thr Ile Ser Ile Thr Lys Ala Gly Val Lys Ala Thr Leu Asn Ala Arg 
                485                 490                 495     


Thr Ser Ile Leu Ala Ala Ala Asn Pro Ile Ser Gly His Tyr Asp Arg 
            500                 505                 510         


Ser Lys Ser Leu Lys Gln Asn Ile Asn Leu Ser Ala Pro Ile Met Ser 
        515                 520                 525             


Arg Phe Asp Leu Phe Phe Ile Leu Val Asp Glu Cys Asn Glu Val Thr 
    530                 535                 540                 


Asp Tyr Ala Ile Ala Arg Arg Ile Val Asp Leu His Ser Arg Ile Glu 
545                 550                 555                 560 


Glu Ser Ile Asp Arg Val Tyr Ser Leu Asp Asp Ile Arg Arg Tyr Leu 
                565                 570                 575     


Leu Phe Ala Arg Gln Phe Lys Pro Lys Ile Ser Lys Glu Ser Glu Asp 
            580                 585                 590         


Phe Ile Val Glu Gln Tyr Lys His Leu Arg Gln Arg Asp Gly Ser Gly 
        595                 600                 605             


Val Thr Lys Ser Ser Trp Arg Ile Thr Val Arg Gln Leu Glu Ser Met 
    610                 615                 620                 


Ile Arg Leu Ser Glu Ala Met Ala Arg Met His Cys Cys Asp Glu Val 
625                 630                 635                 640 


Gln Pro Lys His Val Lys Glu Ala Phe Arg Leu Leu Asn Lys Ser Ile 
                645                 650                 655     


Ile Arg Val Glu Thr Pro Asp Val Asn Leu Asp Gln Glu Glu Glu Ile 
            660                 665                 670         


Gln Met Glu Val Asp Glu Gly Ala Gly Gly Ile Asn Gly His Ala Asp 
        675                 680                 685             


Ser Pro Ala Pro Val Asn Gly Ile Asn Gly Tyr Asn Glu Asp Ile Asn 
    690                 695                 700                 


Gln Glu Ser Ala Pro Lys Ala Ser Leu Arg Leu Gly Phe Ser Glu Tyr 
705                 710                 715                 720 


Cys Arg Ile Ser Asn Leu Ile Val Leu His Leu Arg Lys Val Glu Glu 
                725                 730                 735     


Glu Glu Asp Glu Ser Ala Leu Lys Arg Ser Glu Leu Val Asn Trp Tyr 
            740                 745                 750         


Leu Lys Glu Ile Glu Ser Glu Ile Asp Ser Glu Glu Glu Leu Ile Asn 
        755                 760                 765             


Lys Lys Arg Ile Ile Glu Lys Val Ile His Arg Leu Thr His Tyr Asp 
    770                 775                 780                 


His Val Leu Ile Glu Leu Thr Gln Ala Gly Leu Lys Gly Ser Thr Glu 
785                 790                 795                 800 


Gly Ser Glu Ser Tyr Glu Glu Asp Pro Tyr Leu Val Val Asn Pro Asn 
                805                 810                 815     


Tyr Leu Leu Glu Asp 
            820     


<210>  2824
<211>  1237
<212>  PRT
<213>  homo sapiens

<400>  2824

Met Glu Glu Glu Asp Thr Lys Arg Glu Val Pro Lys Glu Asp Gly Val 
1               5                   10                  15      


Gly Asp Val Gln His Phe Asp Ser Ser Lys Ile Met Glu Glu His Ser 
            20                  25                  30          


Tyr Ile Gln Lys Glu Leu Asp Leu Gln Asn Gly Ser Leu Glu Glu Asp 
        35                  40                  45              


Ser Val Val His Ser Val Glu Asn Asp Ser Gln Asn Met Met Glu Ser 
    50                  55                  60                  


Leu Ser Pro Lys Lys Tyr Ser Ser Ser Leu Arg Phe Lys Ala Asn Gly 
65                  70                  75                  80  


Asp Tyr Ser Gly Ser Tyr Leu Thr Leu Ser Gln Pro Val Pro Ala Lys 
                85                  90                  95      


Arg Ser Pro Ser Pro Leu Gly Thr Ser Val Arg Ser Ser Pro Ser Leu 
            100                 105                 110         


Ala Lys Ile Gln Gly Ser Lys Gln Phe Ser Tyr Asp Gly Thr Asp Lys 
        115                 120                 125             


Asn Ile Pro Met Lys Pro Pro Thr Pro Leu Leu Asn Thr Thr Ser Ser 
    130                 135                 140                 


Leu Ser Gly Tyr Pro Leu Gly Arg Ala Asp Phe Asp His Tyr Thr Gly 
145                 150                 155                 160 


Arg Asp Ser Glu Arg Ala Leu Arg Leu Ser Glu Lys Pro Pro Tyr Ser 
                165                 170                 175     


Lys Tyr Ser Ser Arg His Lys Ser His Asp Asn Val Tyr Ser Leu Gly 
            180                 185                 190         


Gly Leu Glu Gly Arg Lys Ala Ser Gly Ser Leu Leu Ala Met Trp Asn 
        195                 200                 205             


Gly Ser Ser Leu Ser Asp Ala Gly Pro Pro Pro Ile Ser Arg Ser Gly 
    210                 215                 220                 


Ala Ala Ser Met Pro Ser Ser Pro Lys Gln Ala Arg Lys Met Ser Ile 
225                 230                 235                 240 


Gln Asp Ser Leu Ala Leu Gln Pro Lys Leu Thr Arg His Lys Glu Leu 
                245                 250                 255     


Ala Ser Glu Asn Ile Asn Leu Arg Thr Arg Lys Tyr Ser Ser Ser Ser 
            260                 265                 270         


Leu Ser His Met Gly Ala Tyr Ser Arg Ser Leu Pro Arg Leu Tyr Arg 
        275                 280                 285             


Ala Thr Glu Asn Gln Leu Thr Pro Leu Ser Leu Pro Pro Arg Asn Ser 
    290                 295                 300                 


Leu Gly Asn Ser Lys Arg Thr Lys Leu Gly Glu Lys Asp Leu Pro His 
305                 310                 315                 320 


Ser Val Ile Asp Asn Asp Asn Tyr Leu Asn Phe Ser Ser Leu Ser Ser 
                325                 330                 335     


Gly Ala Leu Pro Tyr Lys Thr Ser Ala Ser Glu Gly Asn Pro Tyr Val 
            340                 345                 350         


Ser Ser Thr Leu Ser Val Pro Ala Ser Pro Arg Val Ala Arg Lys Met 
        355                 360                 365             


Leu Leu Ala Ser Thr Ser Ser Cys Ala Ser Asp Asp Phe Asp Gln Ala 
    370                 375                 380                 


Ser Tyr Val Gly Thr Asn Pro Ser His Ser Leu Leu Ala Gly Glu Ser 
385                 390                 395                 400 


Asp Arg Val Phe Ala Thr Arg Arg Asn Phe Ser Cys Gly Ser Val Glu 
                405                 410                 415     


Phe Asp Glu Ala Asp Leu Glu Ser Leu Arg Gln Ala Ser Gly Thr Pro 
            420                 425                 430         


Gln Pro Ala Leu Arg Glu Arg Lys Ser Ser Ile Ser Ser Ile Ser Gly 
        435                 440                 445             


Arg Asp Asp Leu Met Asp Tyr His Arg Arg Gln Arg Glu Glu Arg Leu 
    450                 455                 460                 


Arg Glu Gln Glu Met Glu Arg Leu Glu Arg Gln Arg Leu Glu Thr Ile 
465                 470                 475                 480 


Leu Ser Leu Cys Ala Glu Tyr Thr Lys Pro Asp Ser Arg Leu Ser Thr 
                485                 490                 495     


Gly Thr Thr Val Glu Asp Val Gln Lys Ile Asn Lys Glu Leu Glu Lys 
            500                 505                 510         


Leu Gln Leu Ser Asp Glu Glu Ser Val Phe Glu Glu Ala Leu Met Ser 
        515                 520                 525             


Pro Asp Thr Arg Tyr Arg Cys His Arg Lys Asp Ser Leu Pro Asp Ala 
    530                 535                 540                 


Asp Leu Ala Ser Cys Gly Ser Leu Ser Gln Ser Ser Ala Ser Phe Phe 
545                 550                 555                 560 


Thr Pro Arg Ser Thr Arg Asn Asp Glu Leu Leu Ser Asp Leu Thr Arg 
                565                 570                 575     


Thr Pro Pro Pro Pro Ser Ser Thr Phe Pro Lys Ala Ser Ser Glu Ser 
            580                 585                 590         


Ser Tyr Leu Ser Ile Leu Pro Lys Thr Pro Glu Gly Ile Ser Glu Glu 
        595                 600                 605             


Gln Arg Ser Gln Glu Leu Ala Ala Met Glu Glu Thr Arg Ile Val Ile 
    610                 615                 620                 


Leu Asn Asn Leu Glu Glu Leu Lys Gln Lys Ile Lys Asp Ile Asn Asp 
625                 630                 635                 640 


Gln Met Asp Glu Ser Phe Arg Glu Leu Asp Met Glu Cys Ala Leu Leu 
                645                 650                 655     


Asp Gly Glu Gln Lys Ser Glu Thr Thr Glu Leu Met Lys Glu Lys Glu 
            660                 665                 670         


Ile Leu Asp His Leu Asn Arg Lys Ile Ala Glu Leu Glu Lys Asn Ile 
        675                 680                 685             


Val Gly Glu Lys Thr Lys Asp Ala Asp Leu Leu Asp Val Glu Ser Lys 
    690                 695                 700                 


His Phe Glu Asp Leu Glu Phe Gln Gln Leu Glu His Glu Ser Arg Leu 
705                 710                 715                 720 


Asp Glu Glu Lys Glu Asn Leu Thr Gln Gln Leu Leu Arg Glu Val Ala 
                725                 730                 735     


Glu Tyr Gln Arg Asn Ile Val Ser Arg Lys Glu Lys Ile Ser Ala Leu 
            740                 745                 750         


Lys Lys Gln Ala Asn His Ile Val Gln Gln Ala Gln Arg Glu Gln Asp 
        755                 760                 765             


His Phe Val Lys Glu Lys Asn Asn Leu Ile Met Met Leu Gln Arg Glu 
    770                 775                 780                 


Lys Glu Asn Leu Cys Asn Leu Glu Lys Lys Tyr Ser Ser Leu Ser Gly 
785                 790                 795                 800 


Gly Lys Gly Phe Pro Val Asn Pro Asn Thr Leu Lys Glu Gly Tyr Ile 
                805                 810                 815     


Ser Val Asn Glu Ile Asn Glu Pro Cys Gly Asn Ser Thr Asn Leu Ser 
            820                 825                 830         


Pro Ser Thr Gln Phe Pro Ala Asp Ala Asp Ala Val Ala Thr Glu Pro 
        835                 840                 845             


Ala Thr Ala Val Leu Ala Ser Gln Pro Gln Ser Lys Glu His Phe Arg 
    850                 855                 860                 


Ser Leu Glu Glu Arg Lys Lys Gln His Lys Glu Gly Leu Tyr Leu Ser 
865                 870                 875                 880 


Asp Thr Leu Pro Arg Lys Lys Thr Thr Ser Ser Ile Ser Pro His Phe 
                885                 890                 895     


Ser Ser Ala Thr Met Gly Arg Ser Ile Thr Pro Lys Ala His Leu Pro 
            900                 905                 910         


Leu Gly Gln Ser Asn Ser Cys Gly Ser Val Leu Pro Pro Ser Leu Ala 
        915                 920                 925             


Ala Met Ala Lys Asp Ser Glu Ser Arg Arg Met Leu Arg Gly Tyr Asn 
    930                 935                 940                 


His Gln Gln Met Ser Glu Gly His Arg Gln Lys Ser Glu Phe Tyr Asn 
945                 950                 955                 960 


Arg Thr Ala Ser Glu Ser Asn Val Tyr Leu Asn Ser Phe His Tyr Pro 
                965                 970                 975     


Asp His Ser Tyr Lys Asp Gln Ala Phe Asp Thr Leu Ser Leu Asp Ser 
            980                 985                 990         


Ser Asp Ser Met Glu Thr Ser Ile  Ser Ala Cys Ser Pro  Asp Asn Ile 
        995                 1000                 1005             


Ser Ser  Ala Ser Thr Ser Asn  Ile Ala Arg Ile Glu  Glu Met Glu 
    1010                 1015                 1020             


Arg Leu  Leu Lys Gln Ala His  Ala Glu Lys Thr Arg  Leu Leu Glu 
    1025                 1030                 1035             


Ser Arg  Glu Arg Glu Met Glu  Ala Lys Lys Arg Ala  Leu Glu Glu 
    1040                 1045                 1050             


Glu Lys  Arg Arg Arg Glu Ile  Leu Glu Lys Arg Leu  Gln Glu Glu 
    1055                 1060                 1065             


Thr Ser  Gln Arg Gln Lys Leu  Ile Glu Lys Glu Val  Lys Ile Arg 
    1070                 1075                 1080             


Glu Arg  Gln Arg Ala Gln Ala  Arg Pro Leu Thr Arg  Tyr Leu Pro 
    1085                 1090                 1095             


Val Arg  Lys Glu Asp Phe Asp  Leu Arg Ser His Val  Glu Thr Ala 
    1100                 1105                 1110             


Gly His  Asn Ile Asp Thr Cys  Tyr His Val Ser Ile  Thr Glu Lys 
    1115                 1120                 1125             


Thr Cys  Arg Gly Phe Leu Ile  Lys Met Gly Gly Lys  Ile Lys Thr 
    1130                 1135                 1140             


Trp Lys  Lys Arg Trp Phe Val  Phe Asp Arg Asn Lys  Arg Thr Phe 
    1145                 1150                 1155             


Ser Tyr  Tyr Ala Asp Lys His  Glu Thr Lys Leu Lys  Gly Val Ile 
    1160                 1165                 1170             


Tyr Phe  Gln Ala Ile Glu Glu  Val Tyr Tyr Asp His  Leu Lys Asn 
    1175                 1180                 1185             


Ala Asn  Lys Ser Pro Asn Pro  Leu Leu Thr Phe Ser  Val Lys Thr 
    1190                 1195                 1200             


His Asp  Arg Ile Tyr Tyr Met  Val Ala Pro Ser Pro  Glu Ala Met 
    1205                 1210                 1215             


Arg Ile  Trp Met Asp Val Ile  Val Thr Gly Ala Glu  Gly Tyr Thr 
    1220                 1225                 1230             


His Phe  Leu Leu 
    1235         


<210>  2825
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  2825

Met Ser Asp Asn Asp Asp Ile Glu Val Glu Ser Asp Glu Glu Gln Pro 
1               5                   10                  15      


Arg Phe Gln Ser Ala Ala Asp Lys Arg Ala His His Asn Ala Leu Glu 
            20                  25                  30          


Arg Lys Arg Arg Asp His Ile Lys Asp Ser Phe His Ser Leu Arg Asp 
        35                  40                  45              


Ser Val Pro Ser Leu Gln Gly Glu Lys Ala Ser Arg Ala Gln Ile Leu 
    50                  55                  60                  


Asp Lys Ala Thr Glu Tyr Ile Gln Tyr Met Arg Arg Lys Asn His Thr 
65                  70                  75                  80  


His Gln Gln Asp Ile Asp Asp Leu Lys Arg Gln Asn Ala Leu Leu Glu 
                85                  90                  95      


Gln Gln Gly Glu Ser Glu Ser 
            100             


<210>  2826
<211>  96
<212>  PRT
<213>  homo sapiens

<400>  2826

Met Ser Asp Asn Asp Asp Ile Glu Val Glu Ser Asp Glu Glu Gln Pro 
1               5                   10                  15      


Arg Phe Gln Ser Ala Ala Asp Lys Arg Ala His His Asn Ala Leu Glu 
            20                  25                  30          


Arg Lys Arg Arg Asp His Ile Lys Asp Ser Phe His Ser Leu Arg Asp 
        35                  40                  45              


Ser Val Pro Ser Leu Gln Gly Glu Lys Leu Tyr Phe Leu Phe Trp Lys 
    50                  55                  60                  


Leu Cys Thr Pro Val Leu His Arg Gln Ser Leu Met Gln Lys Cys His 
65                  70                  75                  80  


Thr Phe Ile Ser Ser Tyr Gln Val His Lys Lys Lys Glu Cys Lys Ile 
                85                  90                  95      


<210>  2827
<211>  462
<212>  PRT
<213>  homo sapiens

<400>  2827

Met Ala Ser Asn Ser Ser Ser Cys Pro Thr Pro Gly Gly Gly His Leu 
1               5                   10                  15      


Asn Gly Tyr Pro Val Pro Pro Tyr Ala Phe Phe Phe Pro Pro Met Leu 
            20                  25                  30          


Gly Gly Leu Ser Pro Pro Gly Ala Leu Thr Thr Leu Gln His Gln Leu 
        35                  40                  45              


Pro Val Ser Gly Tyr Ser Thr Pro Ser Pro Ala Thr Ile Glu Thr Gln 
    50                  55                  60                  


Ser Ser Ser Ser Glu Glu Ile Val Pro Ser Pro Pro Ser Pro Pro Pro 
65                  70                  75                  80  


Leu Pro Arg Ile Tyr Lys Pro Cys Phe Val Cys Gln Asp Lys Ser Ser 
                85                  90                  95      


Gly Tyr His Tyr Gly Val Ser Ala Cys Glu Gly Cys Lys Gly Phe Phe 
            100                 105                 110         


Arg Arg Ser Ile Gln Lys Asn Met Val Tyr Thr Cys His Arg Asp Lys 
        115                 120                 125             


Asn Cys Ile Ile Asn Lys Val Thr Arg Asn Arg Cys Gln Tyr Cys Arg 
    130                 135                 140                 


Leu Gln Lys Cys Phe Glu Val Gly Met Ser Lys Glu Ser Val Arg Asn 
145                 150                 155                 160 


Asp Arg Asn Lys Lys Lys Lys Glu Val Pro Lys Pro Glu Cys Ser Glu 
                165                 170                 175     


Ser Tyr Thr Leu Thr Pro Glu Val Gly Glu Leu Ile Glu Lys Val Arg 
            180                 185                 190         


Lys Ala His Gln Glu Thr Phe Pro Ala Leu Cys Gln Leu Gly Lys Tyr 
        195                 200                 205             


Thr Thr Asn Asn Ser Ser Glu Gln Arg Val Ser Leu Asp Ile Asp Leu 
    210                 215                 220                 


Trp Asp Lys Phe Ser Glu Leu Ser Thr Lys Cys Ile Ile Lys Thr Val 
225                 230                 235                 240 


Glu Phe Ala Lys Gln Leu Pro Gly Phe Thr Thr Leu Thr Ile Ala Asp 
                245                 250                 255     


Gln Ile Thr Leu Leu Lys Ala Ala Cys Leu Asp Ile Leu Ile Leu Arg 
            260                 265                 270         


Ile Cys Thr Arg Tyr Thr Pro Glu Gln Asp Thr Met Thr Phe Ser Asp 
        275                 280                 285             


Gly Leu Thr Leu Asn Arg Thr Gln Met His Asn Ala Gly Phe Gly Pro 
    290                 295                 300                 


Leu Thr Asp Leu Val Phe Ala Phe Ala Asn Gln Leu Leu Pro Leu Glu 
305                 310                 315                 320 


Met Asp Asp Ala Glu Thr Gly Leu Leu Ser Ala Ile Cys Leu Ile Cys 
                325                 330                 335     


Gly Asp Arg Gln Asp Leu Glu Gln Pro Asp Arg Val Asp Met Leu Gln 
            340                 345                 350         


Glu Pro Leu Leu Glu Ala Leu Lys Val Tyr Val Arg Lys Arg Arg Pro 
        355                 360                 365             


Ser Arg Pro His Met Phe Pro Lys Met Leu Met Lys Ile Thr Asp Leu 
    370                 375                 380                 


Arg Ser Ile Ser Ala Lys Gly Ala Glu Arg Val Ile Thr Leu Lys Met 
385                 390                 395                 400 


Glu Ile Pro Gly Ser Met Pro Pro Leu Ile Gln Glu Met Leu Glu Asn 
                405                 410                 415     


Ser Glu Gly Leu Asp Thr Leu Ser Gly Gln Pro Gly Gly Gly Gly Arg 
            420                 425                 430         


Asp Gly Gly Gly Leu Ala Pro Pro Pro Gly Ser Cys Ser Pro Ser Leu 
        435                 440                 445             


Ser Pro Ser Ser Asn Arg Ser Ser Pro Ala Thr His Ser Pro 
    450                 455                 460         


<210>  2828
<211>  365
<212>  PRT
<213>  homo sapiens

<400>  2828

Met Ala Ser Asn Ser Ser Ser Cys Pro Thr Pro Gly Gly Gly His Leu 
1               5                   10                  15      


Asn Gly Tyr Pro Val Pro Pro Tyr Ala Phe Phe Phe Pro Pro Met Leu 
            20                  25                  30          


Gly Gly Leu Ser Pro Pro Gly Ala Leu Thr Thr Leu Gln His Gln Leu 
        35                  40                  45              


Pro Val Ser Gly Tyr Ser Thr Pro Ser Pro Ala Thr Val Arg Asn Asp 
    50                  55                  60                  


Arg Asn Lys Lys Lys Lys Glu Val Pro Lys Pro Glu Cys Ser Glu Ser 
65                  70                  75                  80  


Tyr Thr Leu Thr Pro Glu Val Gly Glu Leu Ile Glu Lys Val Arg Lys 
                85                  90                  95      


Ala His Gln Glu Thr Phe Pro Ala Leu Cys Gln Leu Gly Lys Tyr Thr 
            100                 105                 110         


Thr Asn Asn Ser Ser Glu Gln Arg Val Ser Leu Asp Ile Asp Leu Trp 
        115                 120                 125             


Asp Lys Phe Ser Glu Leu Ser Thr Lys Cys Ile Ile Lys Thr Val Glu 
    130                 135                 140                 


Phe Ala Lys Gln Leu Pro Gly Phe Thr Thr Leu Thr Ile Ala Asp Gln 
145                 150                 155                 160 


Ile Thr Leu Leu Lys Ala Ala Cys Leu Asp Ile Leu Ile Leu Arg Ile 
                165                 170                 175     


Cys Thr Arg Tyr Thr Pro Glu Gln Asp Thr Met Thr Phe Ser Asp Gly 
            180                 185                 190         


Leu Thr Leu Asn Arg Thr Gln Met His Asn Ala Gly Phe Gly Pro Leu 
        195                 200                 205             


Thr Asp Leu Val Phe Ala Phe Ala Asn Gln Leu Leu Pro Leu Glu Met 
    210                 215                 220                 


Asp Asp Ala Glu Thr Gly Leu Leu Ser Ala Ile Cys Leu Ile Cys Gly 
225                 230                 235                 240 


Asp Arg Gln Asp Leu Glu Gln Pro Asp Arg Val Asp Met Leu Gln Glu 
                245                 250                 255     


Pro Leu Leu Glu Ala Leu Lys Val Tyr Val Arg Lys Arg Arg Pro Ser 
            260                 265                 270         


Arg Pro His Met Phe Pro Lys Met Leu Met Lys Ile Thr Asp Leu Arg 
        275                 280                 285             


Ser Ile Ser Ala Lys Gly Ala Glu Arg Val Ile Thr Leu Lys Met Glu 
    290                 295                 300                 


Ile Pro Gly Ser Met Pro Pro Leu Ile Gln Glu Met Leu Glu Asn Ser 
305                 310                 315                 320 


Glu Gly Leu Asp Thr Leu Ser Gly Gln Pro Gly Gly Gly Gly Arg Asp 
                325                 330                 335     


Gly Gly Gly Leu Ala Pro Pro Pro Gly Ser Cys Ser Pro Ser Leu Ser 
            340                 345                 350         


Pro Ser Ser Asn Arg Ser Ser Pro Ala Thr His Ser Pro 
        355                 360                 365 


<210>  2829
<211>  1047
<212>  PRT
<213>  homo sapiens

<400>  2829

Met Met Ala Ala Glu Ala Gly Ser Glu Glu Gly Gly Pro Val Thr Ala 
1               5                   10                  15      


Gly Ala Gly Gly Gly Gly Ala Ala Ala Gly Ser Ser Ala Tyr Pro Ala 
            20                  25                  30          


Val Cys Arg Val Lys Ile Pro Ala Ala Leu Pro Val Ala Ala Ala Pro 
        35                  40                  45              


Tyr Pro Gly Leu Val Glu Thr Gly Val Ala Gly Thr Leu Gly Gly Gly 
    50                  55                  60                  


Ala Ala Leu Gly Ser Glu Phe Leu Gly Ala Gly Ser Val Ala Gly Ala 
65                  70                  75                  80  


Leu Gly Gly Ala Gly Leu Thr Gly Gly Gly Thr Ala Ala Gly Val Ala 
                85                  90                  95      


Gly Ala Ala Ala Gly Val Ala Gly Ala Ala Val Ala Gly Pro Ser Gly 
            100                 105                 110         


Asp Met Ala Leu Thr Lys Leu Pro Thr Ser Leu Leu Ala Glu Thr Leu 
        115                 120                 125             


Gly Pro Gly Gly Gly Phe Pro Pro Leu Pro Pro Pro Pro Tyr Leu Pro 
    130                 135                 140                 


Pro Leu Gly Ala Gly Leu Gly Thr Val Asp Glu Gly Asp Ser Leu Asp 
145                 150                 155                 160 


Gly Pro Glu Tyr Glu Glu Glu Glu Val Ala Ile Pro Leu Thr Ala Pro 
                165                 170                 175     


Pro Thr Asn Gln Trp Tyr His Gly Lys Leu Asp Arg Thr Ile Ala Glu 
            180                 185                 190         


Glu Arg Leu Arg Gln Ala Gly Lys Ser Gly Ser Tyr Leu Ile Arg Glu 
        195                 200                 205             


Ser Asp Arg Arg Pro Gly Ser Phe Val Leu Ser Phe Leu Ser Gln Met 
    210                 215                 220                 


Asn Val Val Asn His Phe Arg Ile Ile Ala Met Cys Gly Asp Tyr Tyr 
225                 230                 235                 240 


Ile Gly Gly Arg Arg Phe Ser Ser Leu Ser Asp Leu Ile Gly Tyr Tyr 
                245                 250                 255     


Ser His Val Ser Cys Leu Leu Lys Gly Glu Lys Leu Leu Tyr Pro Val 
            260                 265                 270         


Ala Pro Pro Glu Pro Val Glu Asp Arg Arg Arg Val Arg Ala Ile Leu 
        275                 280                 285             


Pro Tyr Thr Lys Val Pro Asp Thr Asp Glu Ile Ser Phe Leu Lys Gly 
    290                 295                 300                 


Asp Met Phe Ile Val His Asn Glu Leu Glu Asp Gly Trp Met Trp Val 
305                 310                 315                 320 


Thr Asn Leu Arg Thr Asp Glu Gln Gly Leu Ile Val Glu Asp Leu Val 
                325                 330                 335     


Glu Glu Val Gly Arg Glu Glu Asp Pro His Glu Gly Lys Ile Trp Phe 
            340                 345                 350         


His Gly Lys Ile Ser Lys Gln Glu Ala Tyr Asn Leu Leu Met Thr Val 
        355                 360                 365             


Gly Gln Val Cys Ser Phe Leu Val Arg Pro Ser Asp Asn Thr Pro Gly 
    370                 375                 380                 


Asp Tyr Ser Leu Tyr Phe Arg Thr Asn Glu Asn Ile Gln Arg Phe Lys 
385                 390                 395                 400 


Ile Cys Pro Thr Pro Asn Asn Gln Phe Met Met Gly Gly Arg Tyr Tyr 
                405                 410                 415     


Asn Ser Ile Gly Asp Ile Ile Asp His Tyr Arg Lys Glu Gln Ile Val 
            420                 425                 430         


Glu Gly Tyr Tyr Leu Lys Glu Pro Val Pro Met Gln Asp Gln Glu Gln 
        435                 440                 445             


Val Leu Asn Asp Thr Val Asp Gly Lys Glu Ile Tyr Asn Thr Ile Arg 
    450                 455                 460                 


Arg Lys Thr Lys Asp Ala Phe Tyr Lys Asn Ile Val Lys Lys Gly Tyr 
465                 470                 475                 480 


Leu Leu Lys Lys Gly Lys Gly Lys Arg Trp Lys Asn Leu Tyr Phe Ile 
                485                 490                 495     


Leu Glu Gly Ser Asp Ala Gln Leu Ile Tyr Phe Glu Ser Glu Lys Arg 
            500                 505                 510         


Ala Thr Lys Pro Lys Gly Leu Ile Asp Leu Ser Val Cys Ser Val Tyr 
        515                 520                 525             


Val Val His Asp Ser Leu Phe Gly Arg Pro Asn Cys Phe Gln Ile Val 
    530                 535                 540                 


Val Gln His Phe Ser Glu Glu His Tyr Ile Phe Tyr Phe Ala Gly Glu 
545                 550                 555                 560 


Thr Pro Glu Gln Ala Glu Asp Trp Met Lys Gly Leu Gln Ala Phe Cys 
                565                 570                 575     


Asn Leu Arg Lys Ser Ser Pro Gly Thr Ser Asn Lys Arg Leu Arg Gln 
            580                 585                 590         


Val Ser Ser Leu Val Leu His Ile Glu Glu Ala His Lys Leu Pro Val 
        595                 600                 605             


Lys His Phe Thr Asn Pro Tyr Cys Asn Ile Tyr Leu Asn Ser Val Gln 
    610                 615                 620                 


Val Ala Lys Thr His Ala Arg Glu Gly Gln Asn Pro Val Trp Ser Glu 
625                 630                 635                 640 


Glu Phe Val Phe Asp Asp Leu Pro Pro Asp Ile Asn Arg Phe Glu Ile 
                645                 650                 655     


Thr Leu Ser Asn Lys Thr Lys Lys Ser Lys Asp Pro Asp Ile Leu Phe 
            660                 665                 670         


Met Arg Cys Gln Leu Ser Arg Leu Gln Lys Gly His Ala Thr Asp Glu 
        675                 680                 685             


Trp Phe Leu Leu Ser Ser His Ile Pro Leu Lys Gly Ile Glu Pro Gly 
    690                 695                 700                 


Ser Leu Arg Val Arg Ala Arg Tyr Ser Met Glu Lys Ile Met Pro Glu 
705                 710                 715                 720 


Glu Glu Tyr Ser Glu Phe Lys Glu Leu Ile Leu Gln Lys Glu Leu His 
                725                 730                 735     


Val Val Tyr Ala Leu Ser His Val Cys Gly Gln Asp Arg Thr Leu Leu 
            740                 745                 750         


Ala Ser Ile Leu Leu Arg Ile Phe Leu His Glu Lys Leu Glu Ser Leu 
        755                 760                 765             


Leu Leu Cys Thr Leu Asn Asp Arg Glu Ile Ser Met Glu Asp Glu Ala 
    770                 775                 780                 


Thr Thr Leu Phe Arg Ala Thr Thr Leu Ala Ser Thr Leu Met Glu Gln 
785                 790                 795                 800 


Tyr Met Lys Ala Thr Ala Thr Gln Phe Val His His Ala Leu Lys Asp 
                805                 810                 815     


Ser Ile Leu Lys Ile Met Glu Ser Lys Gln Ser Cys Glu Leu Ser Pro 
            820                 825                 830         


Ser Lys Leu Glu Lys Asn Glu Asp Val Asn Thr Asn Leu Thr His Leu 
        835                 840                 845             


Leu Asn Ile Leu Ser Glu Leu Val Glu Lys Ile Phe Met Ala Ser Glu 
    850                 855                 860                 


Ile Leu Pro Pro Thr Leu Arg Tyr Ile Tyr Gly Cys Leu Gln Lys Ser 
865                 870                 875                 880 


Val Gln His Lys Trp Pro Thr Asn Thr Thr Met Arg Thr Arg Val Val 
                885                 890                 895     


Ser Gly Phe Val Phe Leu Arg Leu Ile Cys Pro Ala Ile Leu Asn Pro 
            900                 905                 910         


Arg Met Phe Asn Ile Ile Ser Asp Ser Pro Ser Pro Ile Ala Ala Arg 
        915                 920                 925             


Thr Leu Ile Leu Val Ala Lys Ser Val Gln Asn Leu Ala Asn Leu Val 
    930                 935                 940                 


Glu Phe Gly Ala Lys Glu Pro Tyr Met Glu Gly Val Asn Pro Phe Ile 
945                 950                 955                 960 


Lys Ser Asn Lys His Arg Met Ile Met Phe Leu Asp Glu Leu Gly Asn 
                965                 970                 975     


Val Pro Glu Leu Pro Asp Thr Thr Glu His Ser Arg Thr Asp Leu Ser 
            980                 985                 990         


Arg Asp Leu Ala Ala Leu His Glu  Ile Cys Val Ala His  Ser Asp Glu 
        995                 1000                 1005             


Leu Arg  Thr Leu Ser Asn Glu  Arg Gly Ala Gln Gln  His Val Leu 
    1010                 1015                 1020             


Lys Lys  Leu Leu Ala Ile Thr  Glu Leu Leu Gln Gln  Lys Gln Asn 
    1025                 1030                 1035             


Gln Tyr  Thr Lys Thr Asn Asp  Val Arg 
    1040                 1045         


<210>  2830
<211>  870
<212>  PRT
<213>  homo sapiens

<400>  2830

Met Lys Gly Trp Tyr His Gly Lys Leu Asp Arg Thr Ile Ala Glu Glu 
1               5                   10                  15      


Arg Leu Arg Gln Ala Gly Lys Ser Gly Ser Tyr Leu Ile Arg Glu Ser 
            20                  25                  30          


Asp Arg Arg Pro Gly Ser Phe Val Leu Ser Phe Leu Ser Gln Met Asn 
        35                  40                  45              


Val Val Asn His Phe Arg Ile Ile Ala Met Cys Gly Asp Tyr Tyr Ile 
    50                  55                  60                  


Gly Gly Arg Arg Phe Ser Ser Leu Ser Asp Leu Ile Gly Tyr Tyr Ser 
65                  70                  75                  80  


His Val Ser Cys Leu Leu Lys Gly Glu Lys Leu Leu Tyr Pro Val Ala 
                85                  90                  95      


Pro Pro Glu Pro Val Glu Asp Arg Arg Arg Val Arg Ala Ile Leu Pro 
            100                 105                 110         


Tyr Thr Lys Val Pro Asp Thr Asp Glu Ile Ser Phe Leu Lys Gly Asp 
        115                 120                 125             


Met Phe Ile Val His Asn Glu Leu Glu Asp Gly Trp Met Trp Val Thr 
    130                 135                 140                 


Asn Leu Arg Thr Asp Glu Gln Gly Leu Ile Val Glu Asp Leu Val Glu 
145                 150                 155                 160 


Glu Val Gly Arg Glu Glu Asp Pro His Glu Gly Lys Ile Trp Phe His 
                165                 170                 175     


Gly Lys Ile Ser Lys Gln Glu Ala Tyr Asn Leu Leu Met Thr Val Gly 
            180                 185                 190         


Gln Val Cys Ser Phe Leu Val Arg Pro Ser Asp Asn Thr Pro Gly Asp 
        195                 200                 205             


Tyr Ser Leu Tyr Phe Arg Thr Asn Glu Asn Ile Gln Arg Phe Lys Ile 
    210                 215                 220                 


Cys Pro Thr Pro Asn Asn Gln Phe Met Met Gly Gly Arg Tyr Tyr Asn 
225                 230                 235                 240 


Ser Ile Gly Asp Ile Ile Asp His Tyr Arg Lys Glu Gln Ile Val Glu 
                245                 250                 255     


Gly Tyr Tyr Leu Lys Glu Pro Val Pro Met Gln Asp Gln Glu Gln Val 
            260                 265                 270         


Leu Asn Asp Thr Val Asp Gly Lys Glu Ile Tyr Asn Thr Ile Arg Arg 
        275                 280                 285             


Lys Thr Lys Asp Ala Phe Tyr Lys Asn Ile Val Lys Lys Gly Tyr Leu 
    290                 295                 300                 


Leu Lys Lys Gly Lys Gly Lys Arg Trp Lys Asn Leu Tyr Phe Ile Leu 
305                 310                 315                 320 


Glu Gly Ser Asp Ala Gln Leu Ile Tyr Phe Glu Ser Glu Lys Arg Ala 
                325                 330                 335     


Thr Lys Pro Lys Gly Leu Ile Asp Leu Ser Val Cys Ser Val Tyr Val 
            340                 345                 350         


Val His Asp Ser Leu Phe Gly Arg Pro Asn Cys Phe Gln Ile Val Val 
        355                 360                 365             


Gln His Phe Ser Glu Glu His Tyr Ile Phe Tyr Phe Ala Gly Glu Thr 
    370                 375                 380                 


Pro Glu Gln Ala Glu Asp Trp Met Lys Gly Leu Gln Ala Phe Cys Asn 
385                 390                 395                 400 


Leu Arg Lys Ser Ser Pro Gly Thr Ser Asn Lys Arg Leu Arg Gln Val 
                405                 410                 415     


Ser Ser Leu Val Leu His Ile Glu Glu Ala His Lys Leu Pro Val Lys 
            420                 425                 430         


His Phe Thr Asn Pro Tyr Cys Asn Ile Tyr Leu Asn Ser Val Gln Val 
        435                 440                 445             


Ala Lys Thr His Ala Arg Glu Gly Gln Asn Pro Val Trp Ser Glu Glu 
    450                 455                 460                 


Phe Val Phe Asp Asp Leu Pro Pro Asp Ile Asn Arg Phe Glu Ile Thr 
465                 470                 475                 480 


Leu Ser Asn Lys Thr Lys Lys Ser Lys Asp Pro Asp Ile Leu Phe Met 
                485                 490                 495     


Arg Cys Gln Leu Ser Arg Leu Gln Lys Gly His Ala Thr Asp Glu Trp 
            500                 505                 510         


Phe Leu Leu Ser Ser His Ile Pro Leu Lys Gly Ile Glu Pro Gly Ser 
        515                 520                 525             


Leu Arg Val Arg Ala Arg Tyr Ser Met Glu Lys Ile Met Pro Glu Glu 
    530                 535                 540                 


Glu Tyr Ser Glu Phe Lys Glu Leu Ile Leu Gln Lys Glu Leu His Val 
545                 550                 555                 560 


Val Tyr Ala Leu Ser His Val Cys Gly Gln Asp Arg Thr Leu Leu Ala 
                565                 570                 575     


Ser Ile Leu Leu Arg Ile Phe Leu His Glu Lys Leu Glu Ser Leu Leu 
            580                 585                 590         


Leu Cys Thr Leu Asn Asp Arg Glu Ile Ser Met Glu Asp Glu Ala Thr 
        595                 600                 605             


Thr Leu Phe Arg Ala Thr Thr Leu Ala Ser Thr Leu Met Glu Gln Tyr 
    610                 615                 620                 


Met Lys Ala Thr Ala Thr Gln Phe Val His His Ala Leu Lys Asp Ser 
625                 630                 635                 640 


Ile Leu Lys Ile Met Glu Ser Lys Gln Ser Cys Glu Leu Ser Pro Ser 
                645                 650                 655     


Lys Leu Glu Lys Asn Glu Asp Val Asn Thr Asn Leu Thr His Leu Leu 
            660                 665                 670         


Asn Ile Leu Ser Glu Leu Val Glu Lys Ile Phe Met Ala Ser Glu Ile 
        675                 680                 685             


Leu Pro Pro Thr Leu Arg Tyr Ile Tyr Gly Cys Leu Gln Lys Ser Val 
    690                 695                 700                 


Gln His Lys Trp Pro Thr Asn Thr Thr Met Arg Thr Arg Val Val Ser 
705                 710                 715                 720 


Gly Phe Val Phe Leu Arg Leu Ile Cys Pro Ala Ile Leu Asn Pro Arg 
                725                 730                 735     


Met Phe Asn Ile Ile Ser Asp Ser Pro Ser Pro Ile Ala Ala Arg Thr 
            740                 745                 750         


Leu Ile Leu Val Ala Lys Ser Val Gln Asn Leu Ala Asn Leu Val Glu 
        755                 760                 765             


Phe Gly Ala Lys Glu Pro Tyr Met Glu Gly Val Asn Pro Phe Ile Lys 
    770                 775                 780                 


Ser Asn Lys His Arg Met Ile Met Phe Leu Asp Glu Leu Gly Asn Val 
785                 790                 795                 800 


Pro Glu Leu Pro Asp Thr Thr Glu His Ser Arg Thr Asp Leu Ser Arg 
                805                 810                 815     


Asp Leu Ala Ala Leu His Glu Ile Cys Val Ala His Ser Asp Glu Leu 
            820                 825                 830         


Arg Thr Leu Ser Asn Glu Arg Gly Ala Gln Gln His Val Leu Lys Lys 
        835                 840                 845             


Leu Leu Ala Ile Thr Glu Leu Leu Gln Gln Lys Gln Asn Gln Tyr Thr 
    850                 855                 860                 


Lys Thr Asn Asp Val Arg 
865                 870 


<210>  2831
<211>  1139
<212>  PRT
<213>  homo sapiens

<400>  2831

Met Pro Ser Gly Gly Asp Gln Ser Pro Pro Pro Pro Pro Pro Pro Pro 
1               5                   10                  15      


Ala Ala Ala Ala Ser Asp Glu Glu Glu Glu Asp Asp Gly Glu Ala Glu 
            20                  25                  30          


Asp Ala Ala Pro Pro Ala Glu Ser Pro Thr Pro Gln Ile Gln Gln Arg 
        35                  40                  45              


Phe Asp Glu Leu Cys Ser Arg Leu Asn Met Asp Glu Ala Ala Arg Ala 
    50                  55                  60                  


Glu Ala Trp Asp Ser Tyr Arg Ser Met Ser Glu Ser Tyr Thr Leu Glu 
65                  70                  75                  80  


Gly Asn Asp Leu His Trp Leu Ala Cys Ala Leu Tyr Val Ala Cys Arg 
                85                  90                  95      


Lys Ser Val Pro Thr Val Ser Lys Gly Thr Val Glu Gly Asn Tyr Val 
            100                 105                 110         


Ser Leu Thr Arg Ile Leu Lys Cys Ser Glu Gln Ser Leu Ile Glu Phe 
        115                 120                 125             


Phe Asn Lys Met Lys Lys Trp Glu Asp Met Ala Asn Leu Pro Pro His 
    130                 135                 140                 


Phe Arg Glu Arg Thr Glu Arg Leu Glu Arg Asn Phe Thr Val Ser Ala 
145                 150                 155                 160 


Val Ile Phe Lys Lys Tyr Glu Pro Ile Phe Gln Asp Ile Phe Lys Tyr 
                165                 170                 175     


Pro Gln Glu Glu Gln Pro Arg Gln Gln Arg Gly Arg Lys Gln Arg Arg 
            180                 185                 190         


Gln Pro Cys Thr Val Ser Glu Ile Phe His Phe Cys Trp Val Leu Phe 
        195                 200                 205             


Ile Tyr Ala Lys Gly Asn Phe Pro Met Ile Ser Asp Asp Leu Val Asn 
    210                 215                 220                 


Ser Tyr His Leu Leu Leu Cys Ala Leu Asp Leu Val Tyr Gly Asn Ala 
225                 230                 235                 240 


Leu Gln Cys Ser Asn Arg Lys Glu Leu Val Asn Pro Asn Phe Lys Gly 
                245                 250                 255     


Leu Ser Glu Asp Phe His Ala Lys Asp Ser Lys Pro Ser Ser Asp Pro 
            260                 265                 270         


Pro Cys Ile Ile Glu Lys Leu Cys Ser Leu His Asp Gly Leu Val Leu 
        275                 280                 285             


Glu Ala Lys Gly Ile Lys Glu His Phe Trp Lys Pro Tyr Ile Arg Lys 
    290                 295                 300                 


Leu Tyr Glu Lys Lys Leu Leu Lys Gly Lys Glu Glu Asn Leu Thr Gly 
305                 310                 315                 320 


Phe Leu Glu Pro Gly Asn Phe Gly Glu Ser Phe Lys Ala Ile Asn Lys 
                325                 330                 335     


Ala Tyr Glu Glu Tyr Val Leu Ser Val Gly Asn Leu Asp Glu Arg Ile 
            340                 345                 350         


Phe Leu Gly Glu Asp Ala Glu Glu Glu Ile Gly Thr Leu Ser Arg Cys 
        355                 360                 365             


Leu Asn Ala Gly Ser Gly Thr Glu Thr Ala Glu Arg Val Gln Met Lys 
    370                 375                 380                 


Asn Ile Leu Gln Gln His Phe Asp Lys Ser Lys Ala Leu Arg Ile Ser 
385                 390                 395                 400 


Thr Pro Leu Thr Gly Val Arg Tyr Ile Lys Glu Asn Ser Pro Cys Val 
                405                 410                 415     


Thr Pro Val Ser Thr Ala Thr His Ser Leu Ser Arg Leu His Thr Met 
            420                 425                 430         


Leu Thr Gly Leu Arg Asn Ala Pro Ser Glu Lys Leu Glu Gln Ile Leu 
        435                 440                 445             


Arg Thr Cys Ser Arg Asp Pro Thr Gln Ala Ile Ala Asn Arg Leu Lys 
    450                 455                 460                 


Glu Met Phe Glu Ile Tyr Ser Gln His Phe Gln Pro Asp Glu Asp Phe 
465                 470                 475                 480 


Ser Asn Cys Ala Lys Glu Ile Ala Ser Lys His Phe Arg Phe Ala Glu 
                485                 490                 495     


Met Leu Tyr Tyr Lys Val Leu Glu Ser Val Ile Glu Gln Glu Gln Lys 
            500                 505                 510         


Arg Leu Gly Asp Met Asp Leu Ser Gly Ile Leu Glu Gln Asp Ala Phe 
        515                 520                 525             


His Arg Ser Leu Leu Ala Cys Cys Leu Glu Val Val Thr Phe Ser Tyr 
    530                 535                 540                 


Lys Pro Pro Gly Asn Phe Pro Phe Ile Thr Glu Ile Phe Asp Val Pro 
545                 550                 555                 560 


Leu Tyr His Phe Tyr Lys Val Ile Glu Val Phe Ile Arg Ala Glu Asp 
                565                 570                 575     


Gly Leu Cys Arg Glu Val Val Lys His Leu Asn Gln Ile Glu Glu Gln 
            580                 585                 590         


Ile Leu Asp His Leu Ala Trp Lys Pro Glu Ser Pro Leu Trp Glu Lys 
        595                 600                 605             


Ile Arg Asp Asn Glu Asn Arg Val Pro Thr Cys Glu Glu Val Met Pro 
    610                 615                 620                 


Pro Gln Asn Leu Glu Arg Ala Asp Glu Ile Cys Ile Ala Gly Ser Pro 
625                 630                 635                 640 


Leu Thr Pro Arg Arg Val Thr Glu Val Arg Ala Asp Thr Gly Gly Leu 
                645                 650                 655     


Gly Arg Ser Ile Thr Ser Pro Thr Thr Leu Tyr Asp Arg Tyr Ser Ser 
            660                 665                 670         


Pro Pro Ala Ser Thr Thr Arg Arg Arg Leu Phe Val Glu Asn Asp Ser 
        675                 680                 685             


Pro Ser Asp Gly Gly Thr Pro Gly Arg Met Pro Pro Gln Pro Leu Val 
    690                 695                 700                 


Asn Ala Val Pro Val Gln Asn Val Ser Gly Glu Thr Val Ser Val Thr 
705                 710                 715                 720 


Pro Val Pro Gly Gln Thr Leu Val Thr Met Ala Thr Ala Thr Val Thr 
                725                 730                 735     


Ala Asn Asn Gly Gln Thr Val Thr Ile Pro Val Gln Gly Ile Ala Asn 
            740                 745                 750         


Glu Asn Gly Gly Ile Thr Phe Phe Pro Val Gln Val Asn Val Gly Gly 
        755                 760                 765             


Gln Ala Gln Ala Val Thr Gly Ser Ile Gln Pro Leu Ser Ala Gln Ala 
    770                 775                 780                 


Leu Ala Gly Ser Leu Ser Ser Gln Gln Val Thr Gly Thr Thr Leu Gln 
785                 790                 795                 800 


Val Pro Gly Gln Val Ala Ile Gln Gln Ile Ser Pro Gly Gly Gln Gln 
                805                 810                 815     


Gln Lys Gln Gly Gln Ser Val Thr Ser Ser Ser Asn Arg Pro Arg Lys 
            820                 825                 830         


Thr Ser Ser Leu Ser Leu Phe Phe Arg Lys Val Tyr His Leu Ala Ala 
        835                 840                 845             


Val Arg Leu Arg Asp Leu Cys Ala Lys Leu Asp Ile Ser Asp Glu Leu 
    850                 855                 860                 


Arg Lys Lys Ile Trp Thr Cys Phe Glu Phe Ser Ile Ile Gln Cys Pro 
865                 870                 875                 880 


Glu Leu Met Met Asp Arg His Leu Asp Gln Leu Leu Met Cys Ala Ile 
                885                 890                 895     


Tyr Val Met Ala Lys Val Thr Lys Glu Asp Lys Ser Phe Gln Asn Ile 
            900                 905                 910         


Met Arg Cys Tyr Arg Thr Gln Pro Gln Ala Arg Ser Gln Val Tyr Arg 
        915                 920                 925             


Ser Val Leu Ile Lys Gly Lys Arg Lys Arg Arg Asn Ser Gly Ser Ser 
    930                 935                 940                 


Asp Ser Arg Ser His Gln Asn Ser Pro Thr Glu Leu Asn Lys Asp Arg 
945                 950                 955                 960 


Thr Ser Arg Asp Ser Ser Pro Val Met Arg Ser Ser Ser Thr Leu Pro 
                965                 970                 975     


Val Pro Gln Pro Ser Ser Ala Pro Pro Thr Pro Thr Arg Leu Thr Gly 
            980                 985                 990         


Ala Asn Ser Asp Met Glu Glu Glu  Glu Arg Gly Asp Leu  Ile Gln Phe 
        995                 1000                 1005             


Tyr Asn  Asn Ile Tyr Ile Lys  Gln Ile Lys Thr Phe  Ala Met Lys 
    1010                 1015                 1020             


Tyr Ser  Gln Ala Asn Met Asp  Ala Pro Pro Leu Ser  Pro Tyr Pro 
    1025                 1030                 1035             


Phe Val  Arg Thr Gly Ser Pro  Arg Arg Ile Gln Leu  Ser Gln Asn 
    1040                 1045                 1050             


His Pro  Val Tyr Ile Ser Pro  His Lys Asn Glu Thr  Met Leu Ser 
    1055                 1060                 1065             


Pro Arg  Glu Lys Ile Phe Tyr  Tyr Phe Ser Asn Ser  Pro Ser Lys 
    1070                 1075                 1080             


Arg Leu  Arg Glu Ile Asn Ser  Met Ile Arg Thr Gly  Glu Thr Pro 
    1085                 1090                 1095             


Thr Lys  Lys Arg Gly Ile Leu  Leu Glu Asp Gly Ser  Glu Ser Pro 
    1100                 1105                 1110             


Ala Lys  Arg Ile Cys Pro Glu  Asn His Ser Ala Leu  Leu Arg Arg 
    1115                 1120                 1125             


Leu Gln  Asp Val Ala Asn Asp  Arg Gly Ser His 
    1130                 1135                 


<210>  2832
<211>  593
<212>  PRT
<213>  homo sapiens

<400>  2832

Met Thr Ala Glu Asp Ser Thr Ala Ala Met Ser Ser Asp Ser Ala Ala 
1               5                   10                  15      


Gly Ser Ser Ala Lys Val Pro Glu Gly Val Ala Gly Ala Pro Asn Glu 
            20                  25                  30          


Ala Ala Leu Leu Ala Leu Met Glu Arg Thr Gly Tyr Ser Met Val Gln 
        35                  40                  45              


Glu Asn Gly Gln Arg Lys Tyr Gly Gly Pro Pro Pro Gly Trp Glu Gly 
    50                  55                  60                  


Pro His Pro Gln Arg Gly Cys Glu Val Phe Val Gly Lys Ile Pro Arg 
65                  70                  75                  80  


Asp Val Tyr Glu Asp Glu Leu Val Pro Val Phe Glu Ala Val Gly Arg 
                85                  90                  95      


Ile Tyr Glu Leu Arg Leu Met Met Asp Phe Asp Gly Lys Asn Arg Gly 
            100                 105                 110         


Tyr Ala Phe Val Met Tyr Cys His Lys His Glu Ala Lys Arg Ala Val 
        115                 120                 125             


Arg Glu Leu Asn Asn Tyr Glu Ile Arg Pro Gly Arg Leu Leu Gly Val 
    130                 135                 140                 


Cys Cys Ser Val Asp Asn Cys Arg Leu Phe Ile Gly Gly Ile Pro Lys 
145                 150                 155                 160 


Met Lys Lys Arg Glu Glu Ile Leu Glu Glu Ile Ala Lys Val Thr Glu 
                165                 170                 175     


Gly Val Leu Asp Val Ile Val Tyr Ala Ser Ala Ala Asp Lys Met Lys 
            180                 185                 190         


Asn Arg Gly Phe Ala Phe Val Glu Tyr Glu Ser His Arg Ala Ala Ala 
        195                 200                 205             


Met Ala Arg Arg Lys Leu Met Pro Gly Arg Ile Gln Leu Trp Gly His 
    210                 215                 220                 


Gln Ile Ala Val Asp Trp Ala Glu Pro Glu Ile Asp Val Asp Glu Asp 
225                 230                 235                 240 


Val Met Glu Thr Val Lys Ile Leu Tyr Val Arg Asn Leu Met Ile Glu 
                245                 250                 255     


Thr Thr Glu Asp Thr Ile Lys Lys Ser Phe Gly Gln Phe Asn Pro Gly 
            260                 265                 270         


Cys Val Glu Arg Val Lys Lys Ile Arg Asp Tyr Ala Phe Val His Phe 
        275                 280                 285             


Thr Ser Arg Glu Asp Ala Val His Ala Met Asn Asn Leu Asn Gly Thr 
    290                 295                 300                 


Glu Leu Glu Gly Ser Cys Leu Glu Val Thr Leu Ala Lys Pro Val Asp 
305                 310                 315                 320 


Lys Glu Gln Tyr Ser Arg Tyr Gln Lys Ala Ala Arg Gly Gly Gly Ala 
                325                 330                 335     


Ala Glu Ala Ala Gln Gln Pro Ser Tyr Val Tyr Ser Cys Asp Pro Tyr 
            340                 345                 350         


Thr Leu Ala Tyr Tyr Gly Tyr Pro Tyr Asn Ala Leu Ile Gly Pro Asn 
        355                 360                 365             


Arg Asp Tyr Phe Val Lys Ala Gly Ser Ile Arg Gly Arg Gly Arg Gly 
    370                 375                 380                 


Ala Ala Gly Asn Arg Ala Pro Gly Pro Arg Gly Ser Tyr Leu Gly Gly 
385                 390                 395                 400 


Tyr Ser Ala Gly Arg Gly Ile Tyr Ser Arg Tyr His Glu Gly Lys Gly 
                405                 410                 415     


Lys Gln Gln Glu Lys Gly Tyr Glu Leu Val Pro Asn Leu Glu Ile Pro 
            420                 425                 430         


Thr Val Asn Pro Val Ala Ile Lys Pro Gly Thr Val Ala Ile Pro Ala 
        435                 440                 445             


Ile Gly Ala Gln Tyr Ser Met Phe Pro Ala Ala Pro Ala Pro Lys Met 
    450                 455                 460                 


Ile Glu Asp Gly Lys Ile His Thr Val Glu His Met Ile Ser Pro Ile 
465                 470                 475                 480 


Ala Val Gln Pro Asp Pro Ala Ser Ala Ala Ala Ala Ala Ala Ala Ala 
                485                 490                 495     


Ala Ala Ala Ala Ala Ala Val Ile Pro Thr Val Ser Thr Pro Pro Pro 
            500                 505                 510         


Phe Gln Gly Arg Pro Ile Thr Pro Val Tyr Thr Val Ala Pro Asn Val 
        515                 520                 525             


Gln Arg Ile Pro Thr Ala Gly Ile Tyr Gly Ala Ser Tyr Val Pro Phe 
    530                 535                 540                 


Ala Ala Pro Ala Thr Ala Thr Ile Ala Thr Leu Gln Lys Asn Ala Ala 
545                 550                 555                 560 


Ala Ala Ala Ala Met Tyr Gly Gly Tyr Ala Gly Tyr Ile Pro Gln Ala 
                565                 570                 575     


Phe Pro Ala Ala Ala Ile Gln Val Pro Ile Pro Asp Val Tyr Gln Thr 
            580                 585                 590         


Tyr 
    


<210>  2833
<211>  104
<212>  PRT
<213>  homo sapiens

<400>  2833

Met Lys Ser Cys Gln Lys Met Glu Gly Lys Pro Glu Asn Glu Ser Glu 
1               5                   10                  15      


Pro Lys His Glu Glu Glu Pro Lys Pro Glu Glu Lys Pro Glu Glu Glu 
            20                  25                  30          


Glu Lys Leu Glu Glu Glu Ala Lys Ala Lys Gly Thr Phe Arg Glu Arg 
        35                  40                  45              


Leu Ile Gln Ser Leu Gln Glu Phe Lys Glu Asp Ile His Asn Arg His 
    50                  55                  60                  


Leu Ser Asn Glu Asp Met Phe Arg Glu Val Asp Glu Ile Asp Glu Ile 
65                  70                  75                  80  


Arg Arg Val Arg Asn Lys Leu Ile Val Met Arg Trp Lys Val Asn Arg 
                85                  90                  95      


Asn His Pro Tyr Pro Tyr Leu Met 
            100                 


<210>  2834
<211>  209
<212>  PRT
<213>  homo sapiens

<400>  2834

Met Ser Asn Leu Lys Pro Asp Gly Glu His Gly Gly Ser Thr Gly Thr 
1               5                   10                  15      


Gly Ser Gly Ala Gly Ser Gly Gly Ala Leu Glu Glu Glu Val Arg Thr 
            20                  25                  30          


Leu Phe Val Ser Gly Leu Pro Val Asp Ile Lys Pro Arg Glu Leu Tyr 
        35                  40                  45              


Leu Leu Phe Arg Pro Phe Lys Gly Tyr Glu Gly Ser Leu Ile Lys Leu 
    50                  55                  60                  


Thr Ala Arg Gln Pro Val Gly Phe Val Ile Phe Asp Ser Arg Ala Gly 
65                  70                  75                  80  


Ala Glu Ala Ala Lys Asn Ala Leu Asn Gly Ile Arg Phe Asp Pro Glu 
                85                  90                  95      


Asn Pro Gln Thr Leu Arg Leu Glu Phe Ala Lys Ala Asn Thr Lys Met 
            100                 105                 110         


Ala Lys Ser Lys Leu Met Ala Thr Pro Asn Pro Ser Asn Val His Pro 
        115                 120                 125             


Ala Leu Gly Ala His Phe Ile Ala Arg Asp Pro Tyr Asp Leu Met Gly 
    130                 135                 140                 


Ala Ala Leu Ile Pro Ala Ser Pro Glu Ala Trp Ala Pro Tyr Pro Leu 
145                 150                 155                 160 


Tyr Thr Thr Glu Leu Thr Pro Ala Ile Ser His Ala Ala Phe Thr Tyr 
                165                 170                 175     


Pro Thr Ala Thr Ala Ala Ala Ala Ala Leu His Ala Gln Val Arg Trp 
            180                 185                 190         


Tyr Pro Ser Ser Asp Thr Thr Gln Gln Gly Trp Lys Tyr Arg Gln Phe 
        195                 200                 205             


Cys 
    


<210>  2835
<211>  547
<212>  PRT
<213>  homo sapiens

<400>  2835

Met Phe Tyr Tyr Pro Asn Val Leu Gln Arg His Thr Gly Cys Phe Ala 
1               5                   10                  15      


Thr Ile Trp Leu Ala Ala Thr Arg Gly Ser Arg Leu Val Lys Arg Glu 
            20                  25                  30          


Tyr Leu Arg Val Asn Val Val Lys Thr Cys Glu Glu Ile Leu Asn Tyr 
        35                  40                  45              


Val Leu Val Arg Val Gln Pro Pro Gln Pro Gly Leu Pro Arg Pro Arg 
    50                  55                  60                  


Phe Ser Leu Tyr Leu Ser Ala Gln Leu Gln Ile Gly Val Ile Arg Val 
65                  70                  75                  80  


Tyr Ser Gln Gln Cys Gln Tyr Leu Val Glu Asp Ile Gln His Ile Leu 
                85                  90                  95      


Glu Arg Leu His Arg Ala Gln Leu Gln Ile Arg Ile Asp Met Glu Thr 
            100                 105                 110         


Glu Leu Pro Ser Leu Leu Leu Pro Asn His Leu Ala Met Met Glu Thr 
        115                 120                 125             


Leu Glu Asp Ala Pro Asp Pro Phe Phe Gly Met Met Ser Val Asp Pro 
    130                 135                 140                 


Arg Leu Pro Ser Pro Phe Asp Ile Pro Gln Ile Arg His Leu Leu Glu 
145                 150                 155                 160 


Ala Ala Ile Pro Glu Arg Val Glu Glu Ile Pro Pro Glu Val Pro Thr 
                165                 170                 175     


Glu Pro Arg Glu Pro Glu Arg Ile Pro Val Thr Val Leu Pro Pro Glu 
            180                 185                 190         


Ala Ile Thr Ile Leu Glu Ala Glu Pro Ile Arg Met Leu Glu Ile Glu 
        195                 200                 205             


Gly Glu Arg Glu Leu Pro Glu Val Ser Arg Arg Glu Leu Asp Leu Leu 
    210                 215                 220                 


Ile Ala Glu Glu Glu Glu Ala Ile Leu Leu Glu Ile Pro Arg Leu Pro 
225                 230                 235                 240 


Pro Pro Ala Pro Ala Glu Val Glu Gly Ile Gly Glu Ala Leu Gly Pro 
                245                 250                 255     


Glu Glu Leu Arg Leu Thr Gly Trp Glu Pro Gly Ala Leu Leu Met Glu 
            260                 265                 270         


Val Thr Pro Pro Glu Glu Leu Arg Leu Pro Ala Pro Pro Ser Pro Glu 
        275                 280                 285             


Arg Arg Pro Pro Val Pro Pro Pro Pro Arg Arg Arg Arg Arg Arg Arg 
    290                 295                 300                 


Leu Leu Phe Trp Asp Lys Glu Thr Gln Ile Ser Pro Glu Lys Phe Gln 
305                 310                 315                 320 


Glu Gln Leu Gln Thr Arg Ala His Cys Trp Glu Cys Pro Met Val Gln 
                325                 330                 335     


Pro Pro Glu Arg Thr Ile Arg Gly Pro Ala Glu Leu Phe Arg Thr Pro 
            340                 345                 350         


Thr Leu Ser Gly Trp Leu Pro Pro Glu Leu Leu Gly Leu Trp Thr His 
        355                 360                 365             


Cys Ala Gln Pro Pro Pro Lys Ala Leu Arg Arg Glu Leu Pro Glu Glu 
    370                 375                 380                 


Ala Ala Ala Glu Glu Glu Arg Arg Lys Ile Glu Val Pro Ser Glu Ile 
385                 390                 395                 400 


Glu Val Pro Arg Glu Ala Leu Glu Pro Ser Val Pro Leu Met Val Ser 
                405                 410                 415     


Leu Glu Ile Ser Leu Glu Ala Ala Glu Glu Glu Lys Ser Arg Ile Ser 
            420                 425                 430         


Leu Ile Pro Pro Glu Glu Arg Trp Ala Trp Pro Glu Val Glu Ala Pro 
        435                 440                 445             


Glu Ala Pro Ala Leu Pro Val Val Pro Glu Leu Pro Glu Val Pro Met 
    450                 455                 460                 


Glu Met Pro Leu Val Leu Pro Pro Glu Leu Glu Leu Leu Ser Leu Glu 
465                 470                 475                 480 


Ala Val His Arg Ala Val Ala Leu Glu Leu Gln Ala Asn Arg Glu Pro 
                485                 490                 495     


Asp Phe Ser Ser Leu Val Ser Pro Leu Ser Pro Arg Arg Met Ala Ala 
            500                 505                 510         


Arg Val Phe Tyr Leu Leu Leu Val Leu Ser Ala Gln Gln Ile Leu His 
        515                 520                 525             


Val Lys Gln Glu Lys Pro Tyr Gly Arg Leu Leu Ile Gln Pro Gly Pro 
    530                 535                 540                 


Arg Phe His 
545         


<210>  2836
<211>  1855
<212>  PRT
<213>  homo sapiens

<400>  2836

Met Ala Ala Ser Glu Leu Tyr Thr Lys Phe Ala Arg Val Trp Ile Pro 
1               5                   10                  15      


Asp Pro Glu Glu Val Trp Lys Ser Ala Glu Leu Leu Lys Asp Tyr Lys 
            20                  25                  30          


Pro Gly Asp Lys Val Leu Leu Leu His Leu Glu Glu Gly Lys Asp Leu 
        35                  40                  45              


Glu Tyr His Leu Asp Pro Lys Thr Lys Glu Leu Pro His Leu Arg Asn 
    50                  55                  60                  


Pro Asp Ile Leu Val Gly Glu Asn Asp Leu Thr Ala Leu Ser Tyr Leu 
65                  70                  75                  80  


His Glu Pro Ala Val Leu His Asn Leu Arg Val Arg Phe Ile Asp Ser 
                85                  90                  95      


Lys Leu Ile Tyr Thr Tyr Cys Gly Ile Val Leu Val Ala Ile Asn Pro 
            100                 105                 110         


Tyr Glu Gln Leu Pro Ile Tyr Gly Glu Asp Ile Ile Asn Ala Tyr Ser 
        115                 120                 125             


Gly Gln Asn Met Gly Asp Met Asp Pro His Ile Phe Ala Val Ala Glu 
    130                 135                 140                 


Glu Ala Tyr Lys Gln Met Ala Arg Asp Glu Arg Asn Gln Ser Ile Ile 
145                 150                 155                 160 


Val Ser Gly Glu Ser Gly Ala Gly Lys Thr Val Ser Ala Lys Tyr Ala 
                165                 170                 175     


Met Arg Tyr Phe Ala Thr Val Ser Gly Ser Ala Ser Glu Ala Asn Val 
            180                 185                 190         


Glu Glu Lys Val Leu Ala Ser Asn Pro Ile Met Glu Ser Ile Gly Asn 
        195                 200                 205             


Ala Lys Thr Thr Arg Asn Asp Asn Ser Ser Arg Phe Gly Lys Tyr Ile 
    210                 215                 220                 


Glu Ile Gly Phe Asp Lys Arg Tyr Arg Ile Ile Gly Ala Asn Met Arg 
225                 230                 235                 240 


Thr Tyr Leu Leu Glu Lys Ser Arg Val Val Phe Gln Ala Glu Glu Glu 
                245                 250                 255     


Arg Asn Tyr His Ile Phe Tyr Gln Leu Cys Ala Ser Ala Lys Leu Pro 
            260                 265                 270         


Glu Phe Lys Met Leu Arg Leu Gly Asn Ala Asp Asn Phe Asn Tyr Thr 
        275                 280                 285             


Lys Gln Gly Gly Ser Pro Val Ile Glu Gly Val Asp Asp Ala Lys Glu 
    290                 295                 300                 


Met Ala His Thr Arg Gln Ala Cys Thr Leu Leu Gly Ile Ser Glu Ser 
305                 310                 315                 320 


His Gln Met Gly Ile Phe Arg Ile Leu Ala Gly Ile Leu His Leu Gly 
                325                 330                 335     


Asn Val Gly Phe Thr Ser Arg Asp Ala Asp Ser Cys Thr Ile Pro Pro 
            340                 345                 350         


Lys His Glu Pro Leu Cys Ile Phe Cys Asp Leu Met Gly Val Asp Tyr 
        355                 360                 365             


Glu Glu Met Cys His Trp Leu Cys His Arg Lys Leu Ala Thr Ala Thr 
    370                 375                 380                 


Glu Thr Tyr Ile Lys Pro Ile Ser Lys Leu Gln Ala Thr Asn Ala Arg 
385                 390                 395                 400 


Asp Ala Leu Ala Lys His Ile Tyr Ala Lys Leu Phe Asn Trp Ile Val 
                405                 410                 415     


Asp Asn Val Asn Gln Ala Leu His Ser Ala Val Lys Gln His Ser Phe 
            420                 425                 430         


Ile Gly Val Leu Asp Ile Tyr Gly Phe Glu Thr Phe Glu Ile Asn Ser 
        435                 440                 445             


Phe Glu Gln Phe Cys Ile Asn Tyr Ala Asn Glu Lys Leu Gln Gln Gln 
    450                 455                 460                 


Phe Asn Met His Val Phe Lys Leu Glu Gln Glu Glu Tyr Met Lys Glu 
465                 470                 475                 480 


Gln Ile Pro Trp Thr Leu Ile Asp Phe Tyr Asp Asn Gln Pro Cys Ile 
                485                 490                 495     


Asn Leu Ile Glu Ser Lys Leu Gly Ile Leu Asp Leu Leu Asp Glu Glu 
            500                 505                 510         


Cys Lys Met Pro Lys Gly Thr Asp Asp Thr Trp Ala Gln Lys Leu Tyr 
        515                 520                 525             


Asn Thr His Leu Asn Lys Cys Ala Leu Phe Glu Lys Pro Arg Leu Ser 
    530                 535                 540                 


Asn Lys Ala Phe Ile Ile Gln His Phe Ala Asp Lys Val Glu Tyr Gln 
545                 550                 555                 560 


Cys Glu Gly Phe Leu Glu Lys Asn Lys Asp Thr Val Phe Glu Glu Gln 
                565                 570                 575     


Ile Lys Val Leu Lys Ser Ser Lys Phe Lys Met Leu Pro Glu Leu Phe 
            580                 585                 590         


Gln Asp Asp Glu Lys Ala Ile Ser Pro Thr Ser Ala Thr Ser Ser Gly 
        595                 600                 605             


Arg Thr Pro Leu Thr Arg Thr Pro Ala Lys Pro Thr Lys Gly Arg Pro 
    610                 615                 620                 


Gly Gln Met Ala Lys Glu His Lys Lys Thr Val Gly His Gln Phe Arg 
625                 630                 635                 640 


Asn Ser Leu His Leu Leu Met Glu Thr Leu Asn Ala Thr Thr Pro His 
                645                 650                 655     


Tyr Val Arg Cys Ile Lys Pro Asn Asp Phe Lys Phe Pro Phe Thr Phe 
            660                 665                 670         


Asp Glu Lys Arg Ala Val Gln Gln Leu Arg Ala Cys Gly Val Leu Glu 
        675                 680                 685             


Thr Ile Arg Ile Ser Ala Ala Gly Phe Pro Ser Arg Trp Thr Tyr Gln 
    690                 695                 700                 


Glu Phe Phe Ser Arg Tyr Arg Val Leu Met Lys Gln Lys Asp Val Leu 
705                 710                 715                 720 


Ser Asp Arg Lys Gln Thr Cys Lys Asn Val Leu Glu Lys Leu Ile Leu 
                725                 730                 735     


Asp Lys Asp Lys Tyr Gln Phe Gly Lys Thr Lys Ile Phe Phe Arg Ala 
            740                 745                 750         


Gly Gln Val Ala Tyr Leu Glu Lys Leu Arg Ala Asp Lys Leu Arg Ala 
        755                 760                 765             


Ala Cys Ile Arg Ile Gln Lys Thr Ile Arg Gly Trp Leu Leu Arg Lys 
    770                 775                 780                 


Lys Tyr Leu Arg Met Arg Lys Ala Ala Ile Thr Met Gln Arg Tyr Val 
785                 790                 795                 800 


Arg Gly Tyr Gln Ala Arg Cys Tyr Ala Lys Phe Leu Arg Arg Thr Lys 
                805                 810                 815     


Ala Ala Thr Ile Ile Gln Lys Tyr Trp Arg Met Tyr Val Val Arg Arg 
            820                 825                 830         


Arg Tyr Lys Ile Arg Arg Ala Ala Thr Ile Val Leu Gln Ser Tyr Leu 
        835                 840                 845             


Arg Gly Phe Leu Ala Arg Asn Arg Tyr Arg Lys Ile Leu Arg Glu His 
    850                 855                 860                 


Lys Ala Val Ile Ile Gln Lys Arg Val Arg Gly Trp Leu Ala Arg Thr 
865                 870                 875                 880 


His Tyr Lys Arg Ser Met His Ala Ile Ile Tyr Leu Gln Cys Cys Phe 
                885                 890                 895     


Arg Arg Met Met Ala Lys Arg Glu Leu Lys Lys Leu Lys Ile Glu Ala 
            900                 905                 910         


Arg Ser Val Glu Arg Tyr Lys Lys Leu His Ile Gly Met Glu Asn Lys 
        915                 920                 925             


Ile Met Gln Leu Gln Arg Lys Val Asp Glu Gln Asn Lys Asp Tyr Lys 
    930                 935                 940                 


Cys Leu Val Glu Lys Leu Thr Asn Leu Glu Gly Ile Tyr Asn Ser Glu 
945                 950                 955                 960 


Thr Glu Lys Leu Arg Ser Asp Leu Glu Arg Leu Gln Leu Ser Glu Glu 
                965                 970                 975     


Glu Ala Lys Val Ala Thr Gly Arg Val Leu Ser Leu Gln Glu Glu Ile 
            980                 985                 990         


Ala Lys Leu Arg Lys Asp Leu Glu  Gln Thr Arg Ser Glu  Lys Lys Cys 
        995                 1000                 1005             


Ile Glu  Glu His Ala Asp Arg  Tyr Lys Gln Glu Thr  Glu Gln Leu 
    1010                 1015                 1020             


Val Ser  Asn Leu Lys Glu Glu  Asn Thr Leu Leu Lys  Gln Glu Lys 
    1025                 1030                 1035             


Glu Ala  Leu Asn His Arg Ile  Val Gln Gln Ala Lys  Glu Met Thr 
    1040                 1045                 1050             


Glu Thr  Met Glu Lys Lys Leu  Val Glu Glu Thr Lys  Gln Leu Glu 
    1055                 1060                 1065             


Leu Asp  Leu Asn Asp Glu Arg  Leu Arg Tyr Gln Asn  Leu Leu Asn 
    1070                 1075                 1080             


Glu Phe  Ser Arg Leu Glu Glu  Arg Tyr Asp Asp Leu  Lys Glu Glu 
    1085                 1090                 1095             


Met Thr  Leu Met Val His Val  Pro Lys Pro Gly His  Lys Arg Thr 
    1100                 1105                 1110             


Asp Ser  Thr His Ser Ser Asn  Glu Ser Glu Tyr Ile  Phe Ser Ser 
    1115                 1120                 1125             


Glu Ile  Ala Glu Met Glu Asp  Ile Pro Ser Arg Thr  Glu Glu Pro 
    1130                 1135                 1140             


Ser Glu  Lys Lys Val Pro Leu  Asp Met Ser Leu Phe  Leu Lys Leu 
    1145                 1150                 1155             


Gln Lys  Arg Val Thr Glu Leu  Glu Gln Glu Lys Gln  Val Met Gln 
    1160                 1165                 1170             


Asp Glu  Leu Asp Arg Lys Glu  Glu Gln Val Leu Arg  Ser Lys Ala 
    1175                 1180                 1185             


Lys Glu  Glu Glu Arg Pro Gln  Ile Arg Gly Ala Glu  Leu Glu Tyr 
    1190                 1195                 1200             


Glu Ser  Leu Lys Arg Gln Glu  Leu Glu Ser Glu Asn  Lys Lys Leu 
    1205                 1210                 1215             


Lys Asn  Glu Leu Asn Glu Leu  Arg Lys Ala Leu Ser  Glu Lys Ser 
    1220                 1225                 1230             


Ala Pro  Glu Val Thr Ala Pro  Gly Ala Pro Ala Tyr  Arg Val Leu 
    1235                 1240                 1245             


Met Glu  Gln Leu Thr Ser Val  Ser Glu Glu Leu Asp  Val Arg Lys 
    1250                 1255                 1260             


Glu Glu  Val Leu Ile Leu Arg  Ser Gln Leu Val Ser  Gln Lys Glu 
    1265                 1270                 1275             


Ala Ile  Gln Pro Lys Asp Asp  Lys Asn Thr Met Thr  Asp Ser Thr 
    1280                 1285                 1290             


Ile Leu  Leu Glu Asp Val Gln  Lys Met Lys Asp Lys  Gly Glu Ile 
    1295                 1300                 1305             


Ala Gln  Ala Tyr Ile Gly Leu  Lys Glu Thr Asn Arg  Ser Ser Ala 
    1310                 1315                 1320             


Leu Asp  Tyr His Glu Leu Asn  Glu Asp Gly Glu Leu  Trp Leu Val 
    1325                 1330                 1335             


Tyr Glu  Gly Leu Lys Gln Ala  Asn Arg Leu Leu Glu  Ser Gln Leu 
    1340                 1345                 1350             


Gln Ser  Gln Lys Arg Ser His  Glu Asn Glu Ala Glu  Ala Leu Arg 
    1355                 1360                 1365             


Gly Glu  Ile Gln Ser Leu Lys  Glu Glu Asn Asn Arg  Gln Gln Gln 
    1370                 1375                 1380             


Leu Leu  Ala Gln Asn Leu Gln  Leu Pro Pro Glu Ala  Arg Ile Glu 
    1385                 1390                 1395             


Ala Ser  Leu Gln His Glu Ile  Thr Arg Leu Thr Asn  Glu Asn Leu 
    1400                 1405                 1410             


Asp Leu  Met Glu Gln Leu Glu  Lys Gln Asp Lys Thr  Val Arg Lys 
    1415                 1420                 1425             


Leu Lys  Lys Gln Leu Lys Val  Phe Ala Lys Lys Ile  Gly Glu Leu 
    1430                 1435                 1440             


Glu Val  Gly Gln Met Glu Asn  Ile Ser Pro Gly Gln  Ile Ile Asp 
    1445                 1450                 1455             


Glu Pro  Ile Arg Pro Val Asn  Ile Pro Arg Lys Glu  Lys Asp Phe 
    1460                 1465                 1470             


Gln Gly  Met Leu Glu Tyr Lys  Lys Glu Asp Glu Gln  Lys Leu Val 
    1475                 1480                 1485             


Lys Asn  Leu Ile Leu Glu Leu  Lys Pro Arg Gly Val  Ala Val Asn 
    1490                 1495                 1500             


Leu Ile  Pro Gly Leu Pro Ala  Tyr Ile Leu Phe Met  Cys Val Arg 
    1505                 1510                 1515             


His Ala  Asp Tyr Leu Asn Asp  Asp Gln Lys Val Arg  Ser Leu Leu 
    1520                 1525                 1530             


Thr Ser  Thr Ile Asn Ser Ile  Lys Lys Val Leu Lys  Lys Arg Gly 
    1535                 1540                 1545             


Asp Asp  Phe Glu Thr Val Ser  Phe Trp Leu Ser Asn  Thr Cys Arg 
    1550                 1555                 1560             


Phe Leu  His Cys Leu Lys Gln  Tyr Ser Gly Glu Glu  Gly Phe Met 
    1565                 1570                 1575             


Lys His  Asn Thr Ser Arg Gln  Asn Glu His Cys Leu  Thr Asn Phe 
    1580                 1585                 1590             


Asp Leu  Ala Glu Tyr Arg Gln  Val Leu Ser Asp Leu  Ala Ile Gln 
    1595                 1600                 1605             


Ile Tyr  Gln Gln Leu Val Arg  Val Leu Glu Asn Ile  Leu Gln Pro 
    1610                 1615                 1620             


Met Ile  Val Ser Gly Met Leu  Glu His Glu Thr Ile  Gln Gly Val 
    1625                 1630                 1635             


Ser Gly  Val Lys Pro Thr Gly  Leu Arg Lys Arg Thr  Ser Ser Ile 
    1640                 1645                 1650             


Ala Asp  Glu Gly Thr Tyr Thr  Leu Asp Ser Ile Leu  Arg Gln Leu 
    1655                 1660                 1665             


Asn Ser  Phe His Ser Val Met  Cys Gln His Gly Met  Asp Pro Glu 
    1670                 1675                 1680             


Leu Ile  Lys Gln Val Val Lys  Gln Met Phe Tyr Ile  Ile Gly Ala 
    1685                 1690                 1695             


Ile Thr  Leu Asn Asn Leu Leu  Leu Arg Lys Asp Met  Cys Ser Trp 
    1700                 1705                 1710             


Ser Lys  Gly Met Gln Ile Arg  Tyr Asn Val Ser Gln  Leu Glu Glu 
    1715                 1720                 1725             


Trp Leu  Arg Asp Lys Asn Leu  Met Asn Ser Gly Ala  Lys Glu Thr 
    1730                 1735                 1740             


Leu Glu  Pro Leu Ile Gln Ala  Ala Gln Leu Leu Gln  Val Lys Lys 
    1745                 1750                 1755             


Lys Thr  Asp Asp Asp Ala Glu  Ala Ile Cys Ser Met  Cys Asn Ala 
    1760                 1765                 1770             


Leu Thr  Thr Ala Gln Ile Val  Lys Val Leu Asn Leu  Tyr Thr Pro 
    1775                 1780                 1785             


Val Asn  Glu Phe Glu Glu Arg  Val Ser Val Ser Phe  Ile Arg Thr 
    1790                 1795                 1800             


Ile Gln  Met Arg Leu Arg Asp  Arg Lys Asp Ser Pro  Gln Leu Leu 
    1805                 1810                 1815             


Met Asp  Ala Lys His Ile Phe  Pro Val Thr Phe Pro  Phe Asn Pro 
    1820                 1825                 1830             


Ser Ser  Leu Ala Leu Glu Thr  Ile Gln Ile Pro Ala  Ser Leu Gly 
    1835                 1840                 1845             


Leu Gly  Phe Ile Ser Arg Val  
    1850                 1855 


<210>  2837
<211>  104
<212>  PRT
<213>  homo sapiens

<400>  2837

Met Lys Ser Cys Gln Lys Met Glu Gly Lys Pro Glu Asn Glu Ser Glu 
1               5                   10                  15      


Pro Lys His Glu Glu Glu Pro Lys Pro Glu Glu Lys Pro Glu Glu Glu 
            20                  25                  30          


Glu Lys Leu Glu Glu Glu Ala Lys Ala Lys Gly Thr Phe Arg Glu Arg 
        35                  40                  45              


Leu Ile Gln Ser Leu Gln Glu Phe Lys Glu Asp Ile His Asn Arg His 
    50                  55                  60                  


Leu Ser Asn Glu Asp Met Phe Arg Glu Val Asp Glu Ile Asp Glu Ile 
65                  70                  75                  80  


Arg Arg Val Arg Asn Lys Leu Ile Val Met Arg Trp Lys Val Asn Arg 
                85                  90                  95      


Asn His Pro Tyr Pro Tyr Leu Met 
            100                 


<210>  2838
<211>  104
<212>  PRT
<213>  homo sapiens

<400>  2838

Met Lys Ser Cys Gln Lys Met Glu Gly Lys Pro Glu Asn Glu Ser Glu 
1               5                   10                  15      


Pro Lys His Glu Glu Glu Pro Lys Pro Glu Glu Lys Pro Glu Glu Glu 
            20                  25                  30          


Glu Lys Leu Glu Glu Glu Ala Lys Ala Lys Gly Thr Phe Arg Glu Arg 
        35                  40                  45              


Leu Ile Gln Ser Leu Gln Glu Phe Lys Glu Asp Ile His Asn Arg His 
    50                  55                  60                  


Leu Ser Asn Glu Asp Met Phe Arg Glu Val Asp Glu Ile Asp Glu Ile 
65                  70                  75                  80  


Arg Arg Val Arg Asn Lys Leu Ile Val Met Arg Trp Lys Val Asn Arg 
                85                  90                  95      


Asn His Pro Tyr Pro Tyr Leu Met 
            100                 


<210>  2839
<211>  1742
<212>  PRT
<213>  homo sapiens

<400>  2839

Met Trp Pro Ala Gly Ala Gly Thr Lys Leu Pro Cys Pro Arg Asp Ser 
1               5                   10                  15      


Ala Leu Arg Arg Ala Ala Phe Ser Gly Asn Leu Thr Ala Leu Pro Ser 
            20                  25                  30          


His Leu Val Pro Ala Gly Arg Ser Val Arg Val Phe Ile Ser Ala Asn 
        35                  40                  45              


Pro Glu Asp Thr Gly Ala Glu Arg Gln Ala Leu Arg Glu Asn Val Tyr 
    50                  55                  60                  


Pro Lys Leu Arg Glu Phe Cys Arg Glu Asn Tyr Gly Leu Glu Phe Gln 
65                  70                  75                  80  


Val Ile Asp Leu Tyr Trp Gly Val Glu Glu Asp Glu Trp Asp Ser Pro 
                85                  90                  95      


Glu Leu Gln Lys Thr Arg Met Lys Leu Leu Glu Asn Cys Leu Lys Thr 
            100                 105                 110         


Ser Ala Gly Pro Cys Phe Val Gly Leu Leu Gly Glu Lys Tyr Gly Asn 
        115                 120                 125             


Ile Arg Ile Pro Gly Glu Val Glu Ala Ser Glu Phe Glu Met Ile Leu 
    130                 135                 140                 


Asp Ala Ala Ile Glu Ala Lys Leu Glu Thr Lys Leu Leu Glu Glu Trp 
145                 150                 155                 160 


Tyr Cys Arg Asp Glu Asn Ser Val Pro Ala Ala Tyr Tyr Leu Arg Pro 
                165                 170                 175     


Lys Ser Glu Met Leu Arg Ser Asn Arg Asn Ala Met Gln Pro Ser Thr 
            180                 185                 190         


Asn Ala Glu Asn Glu Lys Thr Trp Gln Glu Ile Ser Asp Glu Ile Lys 
        195                 200                 205             


Lys Ile Phe Lys Ala Ala Val Lys Leu Leu His Glu Lys Gly Lys Met 
    210                 215                 220                 


Lys His Ser Gln Ala Lys Arg Tyr Leu Phe Ser Ala Ile Glu Asp Glu 
225                 230                 235                 240 


Phe Asp Phe Ala Leu Gly Lys Gln Thr Pro Ala Phe Leu Lys Lys Cys 
                245                 250                 255     


Val Cys Tyr Ile Arg Lys Ile Ala Asn Ile Glu Arg Phe Val Lys Ile 
            260                 265                 270         


Pro Glu Met Gly Lys Tyr Met Asp Ile Thr Gly Thr Glu Pro Arg Ile 
        275                 280                 285             


Ile Arg Asp Pro Glu Ala Gln Glu Lys Leu Ile Lys Leu Arg Asp Glu 
    290                 295                 300                 


Phe Ile Pro Thr Ile Val Ala Ser Ser Asn Leu Arg Val Tyr Thr Ser 
305                 310                 315                 320 


Val Thr His Cys Asp Met Lys Leu Gly Tyr Ser Gln Glu Ile Glu Asn 
                325                 330                 335     


His Tyr Ile Glu Gly Leu Gly Lys Gln Phe Tyr Glu Asp Met Ile Asp 
            340                 345                 350         


Ile Ile Gln Ala Thr Ile Gln Gln Asn Phe Asp Thr Glu Thr Asp Thr 
        355                 360                 365             


Leu Tyr Asp Glu Ile Leu Gln His Ser Ser Leu Cys Lys Thr Tyr Ala 
    370                 375                 380                 


Ser Phe Tyr Glu Tyr Lys Cys Glu Ser Leu Asn Ile Val His Asn Tyr 
385                 390                 395                 400 


Ile Leu Pro Ser Lys Ala Gly His Ile Asn Pro Leu Ile Ile Tyr Gly 
                405                 410                 415     


Gly Pro Cys Thr Gly Lys Thr Leu Leu Leu Ala Glu Val Ala Lys Lys 
            420                 425                 430         


Ala Tyr Gly Trp Leu His Glu Asp Thr Gly Pro Glu Ser Asp Pro Val 
        435                 440                 445             


Val Ile Val Arg Phe Leu Gly Thr Thr Asp Met Ser Ser Asp Leu Arg 
    450                 455                 460                 


Thr Leu Leu Leu Ser Val Cys Glu Gln Leu Ala Val Asn Tyr Arg Cys 
465                 470                 475                 480 


Leu Val Gln Ser Tyr Pro Lys Lys Ile His Asp Leu Cys Asp Leu Phe 
                485                 490                 495     


Ile Asn Leu Leu Asn Glu Ser Ser Leu Gln Arg Pro Leu Val Ile Ile 
            500                 505                 510         


Phe Asp Ala Leu Glu Gln Leu Ser Glu Asn Asp Asp Ala Arg Lys Leu 
        515                 520                 525             


Trp Trp Leu Pro Ala His Leu Pro Arg Phe Val Arg Ile Val Leu Ser 
    530                 535                 540                 


Thr Leu Pro Asn Lys His Gly Ile Leu Gln Lys Leu Arg Cys Leu Ile 
545                 550                 555                 560 


His Glu Glu Asp Asn Tyr Ile Glu Leu Ile Pro Arg Asp Arg Lys Met 
                565                 570                 575     


Cys Ser Gln Val Leu Lys His Gln Leu Leu Arg Val Lys Arg Lys Val 
            580                 585                 590         


Thr Ser Gly Gln Gln Ile Tyr Val Asn Asn Ala Leu Ser Lys Cys Thr 
        595                 600                 605             


Leu Pro Met Phe Val Asn Leu Thr Phe Arg Glu Val Arg His Trp Arg 
    610                 615                 620                 


Ser His Lys Asp Val Asp Glu Ser Ser Leu Ser Val Thr Val His Glu 
625                 630                 635                 640 


Ser Ile Glu Gln Leu Phe Trp Ser Leu Glu Lys Lys Cys Gly Gln Lys 
                645                 650                 655     


Leu Val Ser Arg Ala Leu Gly Tyr Ile Thr Met Ala Lys Met Gly Leu 
            660                 665                 670         


Ser Glu Met Glu Leu Glu Asp Val Leu Ala Leu Asp Asn Ser Val Met 
        675                 680                 685             


Ser Glu Leu Lys Glu Asn Thr Arg Pro Ser Asn Pro Leu Arg Val Pro 
    690                 695                 700                 


Tyr Leu Tyr Ile Ala Arg Leu Lys Glu Gly Leu Ser Gly Tyr Leu Ile 
705                 710                 715                 720 


Glu Arg His Val Lys Asn Val Thr Leu Leu Val Trp Ala Asn Arg His 
                725                 730                 735     


Leu Gln Leu Ile Ala Gln Lys Leu Tyr Leu Gln Asp Asp Asn Asp Leu 
            740                 745                 750         


Arg Glu Met His Thr Ile Leu Ala Asp Tyr Phe Leu Gly Val Trp Ser 
        755                 760                 765             


Gly Gly Arg Arg Lys Ala Phe Cys Leu Glu Asp Pro Tyr Leu Asn Gly 
    770                 775                 780                 


Cys Leu Asp Leu Glu Asn Arg Ser Leu Leu Glu Glu Glu Lys His Phe 
785                 790                 795                 800 


Met Glu Gln Ala Ser Phe Asp Arg Gln Ala Pro Asp Gln Pro Trp Val 
                805                 810                 815     


Phe Gln Cys Asn Pro Leu Glu Pro Asp Ile Phe Phe Val Asn His Arg 
            820                 825                 830         


Lys Met Ser Glu Leu Leu Tyr His Leu Thr Arg Cys Gly Lys Thr Asp 
        835                 840                 845             


Asp Leu Leu Tyr Gly Ile Ile Met Asn Phe Ser Trp Leu Tyr Thr Met 
    850                 855                 860                 


Ile Lys Ile Gly Gln Phe Asp Lys Val Leu Ser Asp Ile Glu Leu Ala 
865                 870                 875                 880 


Tyr Asn Tyr Ser Gln Glu Lys Glu Leu Lys Phe Leu Ala Asn Thr Leu 
                885                 890                 895     


Arg Ser Ile Lys Asn Lys Val Thr Ala Phe Pro Gly Ser Leu Ser Ala 
            900                 905                 910         


Glu Leu Gln Gln Arg Leu Leu Pro Val Val Ser Ser Leu Pro Lys Leu 
        915                 920                 925             


Arg His Leu Leu Leu Glu Cys Asp Lys Asp Gly Pro Lys Tyr Cys Ser 
    930                 935                 940                 


Ile Val Pro Leu His Ser Ser Met Asp Val Thr Tyr Ser Pro Glu Arg 
945                 950                 955                 960 


Leu Pro Leu Ser Ser Ser His Leu His Val Thr Glu Ile Leu Pro Thr 
                965                 970                 975     


Cys Asn Pro Ser Thr Val Leu Thr Ala Leu Glu Asn Gly Ser Ile Ser 
            980                 985                 990         


Thr Trp Asp Val Glu Thr Arg Gln  Leu Leu Arg Gln Ile  Thr Thr Ala 
        995                 1000                 1005             


Gln Ser  Val Ile Leu Gly Met  Lys Leu Thr Ser Asp  Glu Lys Tyr 
    1010                 1015                 1020             


Leu Val  Val Ala Thr Thr Asn  Asn Thr Leu Leu Ile  Tyr Asp Asn 
    1025                 1030                 1035             


Val Asn  Ser Cys Leu Leu Ser  Glu Val Glu Ile Lys  Gly Thr Lys 
    1040                 1045                 1050             


His Gly  Ser Ser Ala Thr Tyr  Ile Asn Gly Phe Thr  Leu Ser Ala 
    1055                 1060                 1065             


Asn His  Ala Leu Ala Trp Leu  Glu Ala Ser Lys Asp  Val Thr Val 
    1070                 1075                 1080             


Ile Asp  Leu Leu Tyr Gly Trp  Pro Leu Tyr Gln Phe  His Cys Trp 
    1085                 1090                 1095             


Tyr Glu  Val Thr Cys Val Gln  Cys Ser Leu Asp Gly  Leu Tyr Ala 
    1100                 1105                 1110             


Phe Cys  Gly Gln Tyr Leu Asn  Thr Thr Thr Ile Phe  His Leu Gly 
    1115                 1120                 1125             


Ser Gly  Glu Lys Leu Cys Thr  Val Thr Ser Glu Phe  Ser Gly Gly 
    1130                 1135                 1140             


Phe Val  Lys Phe Leu Leu Ile  Leu Asp Thr Ala Gln  Glu Met Val 
    1145                 1150                 1155             


Met Val  Asp Ser Glu Gly Ser  Leu Ser Val Trp Asn  Thr Glu Asp 
    1160                 1165                 1170             


Ile Ser  Ser Pro Gln Leu Thr  Asp Asp Phe Asp Cys  Arg Arg Glu 
    1175                 1180                 1185             


Asp Ser  Glu Val Val Ser Ile  Glu Leu Ser Glu Asp  Gln Ser Ala 
    1190                 1195                 1200             


Val Leu  Ile Cys Lys Ala Leu  Ser Ile Glu Leu Leu  Asp Thr Gly 
    1205                 1210                 1215             


Leu Trp  Lys Val Ala Glu Lys  Phe Arg Ala Lys His  Asn Glu Arg 
    1220                 1225                 1230             


Phe Ile  Ser Ala Val Leu Ser  Lys Asn Gly Asp Cys  Ile Ile Ala 
    1235                 1240                 1245             


Thr Met  Glu Asn Thr Ser Ala  Val Phe Phe Trp Arg  Arg Asp Thr 
    1250                 1255                 1260             


Gly Gln  Cys Met Ala Ser Leu  Gln Glu Ile Ser Gly  Ser Ile Val 
    1265                 1270                 1275             


Lys Leu  Val Lys Ser Ser His  His Asn Met Leu Leu  Ser Leu Ser 
    1280                 1285                 1290             


Thr Ser  Gly Val Leu Ser Ile  Trp Asp Ile Asp Ile  Ile Thr Ala 
    1295                 1300                 1305             


Met Ser  Asn Ile Asp Lys Thr  Gly Lys Pro Ile Gln  Ser Leu Leu 
    1310                 1315                 1320             


Leu Pro  Ala Arg Gly Glu Ile  Ile Tyr Ser Leu Asp  Gly Ser Asp 
    1325                 1330                 1335             


Cys Val  His Lys Trp Asn Phe  Ser Ser Gly Phe Ile  Glu Ala Val 
    1340                 1345                 1350             


Phe Lys  His Glu Gly Ile Val  Glu His Cys Val Leu  Thr Ser Thr 
    1355                 1360                 1365             


Gly Asp  Ile Met Val Thr Ser  Asp Asp Lys Ser Ser  Gln Tyr Val 
    1370                 1375                 1380             


Trp His  Thr Ser Ser Gly Glu  Asn Leu Phe Arg Ile  Asn Gly Gln 
    1385                 1390                 1395             


Arg Ile  Ser Gln Leu Leu Ile  Thr His Asn Asp Gln  Phe Val Val 
    1400                 1405                 1410             


Ser Leu  Cys Glu Glu Asn Ala  Ser Arg Val Trp Arg  Leu Ala Thr 
    1415                 1420                 1425             


Gly His  Arg Val Cys Asn Ile  Leu Thr Thr Leu Gln  Asn Ala Phe 
    1430                 1435                 1440             


Ile Thr  Ser Ala Asn Thr Phe  Val Val Gly Met Thr  Lys Ser Lys 
    1445                 1450                 1455             


Val Leu  Ala Val Ser Leu Trp  Thr Gly Ser Ile Thr  Lys Lys Phe 
    1460                 1465                 1470             


Cys Cys  Glu Asp Gly Thr Thr  Ile Val Asn Phe Lys  Leu Ile Pro 
    1475                 1480                 1485             


Asp Cys  Pro Asp Ile Ile Val  Phe Ile Thr Ser Ala  Glu Thr Val 
    1490                 1495                 1500             


Asn Ile  Trp Ser Leu Thr Asp  Glu Val Ile Cys Arg  Arg Val Gln 
    1505                 1510                 1515             


Leu Pro  Asn Asn Phe Leu Lys  Asn Leu Glu Asp Phe  Glu Ile Ser 
    1520                 1525                 1530             


Pro Asn  Gly Lys Leu Gly Ile  Ile Ala Arg Gly Asp  Glu Asn Ile 
    1535                 1540                 1545             


Asn Val  Leu Asp Leu Tyr Ser  Gly Lys Leu Arg Val  Val His Ala 
    1550                 1555                 1560             


Ser Gly  Ile Ile Trp Arg Gln  Arg Leu Ser Arg Asp  Gly Arg Tyr 
    1565                 1570                 1575             


Leu Val  Tyr Ile Cys Phe Arg  Asn Gly Glu Glu Glu  Asp Glu Asn 
    1580                 1585                 1590             


Gly Ala  Ile Phe Ser Leu Ile  Val Met Arg Leu Ala  Asp Gly Lys 
    1595                 1600                 1605             


Asn Ile  Gly Ala Cys Ser Leu  Tyr Lys Thr Pro Thr  Phe Leu Ala 
    1610                 1615                 1620             


Leu Ser  Gln Arg His Leu Asn  Ile Ile Val Gly Phe  Asp Asp Gly 
    1625                 1630                 1635             


Ser Ile  Gly Ile Tyr Thr Val  Val Asp Arg Val Asp  Ala Ala Leu 
    1640                 1645                 1650             


Lys Ile  Lys Ile Ala Thr Ser  Asn Ser Arg Gln Ile  Phe Asn Asn 
    1655                 1660                 1665             


Ala Thr  His Thr Ser Arg Pro  Lys Cys Asn Ser Tyr  Cys Phe Lys 
    1670                 1675                 1680             


Ile Ser  Val Asp Cys Leu Trp  Arg Glu Ser Thr Glu  Val Phe Ala 
    1685                 1690                 1695             


Arg Asp  Ser Pro Ile Thr Val  Ser Asp Ser Thr Glu  Ser Asn Glu 
    1700                 1705                 1710             


Ala Thr  Pro Ser Lys Lys His  Asn Ser Cys Tyr Glu  Arg Val Cys 
    1715                 1720                 1725             


Ser Ala  Leu Glu Ala Arg Gly  His Ser Tyr Ala Pro  Asp Asn 
    1730                 1735                 1740         


<210>  2840
<211>  621
<212>  PRT
<213>  homo sapiens

<400>  2840

Met Ala Asn Val Pro Trp Ala Glu Val Cys Glu Lys Phe Gln Ala Ala 
1               5                   10                  15      


Leu Ala Leu Ser Arg Val Glu Leu His Lys Asn Pro Glu Lys Glu Pro 
            20                  25                  30          


Tyr Lys Ser Lys Tyr Ser Ala Arg Ala Leu Leu Glu Glu Val Lys Ala 
        35                  40                  45              


Leu Leu Gly Pro Ala Pro Glu Asp Glu Asp Glu Arg Pro Glu Ala Glu 
    50                  55                  60                  


Asp Gly Pro Gly Ala Gly Asp His Ala Leu Gly Leu Pro Ala Glu Val 
65                  70                  75                  80  


Val Glu Pro Glu Gly Pro Val Ala Gln Arg Ala Val Arg Leu Ala Val 
                85                  90                  95      


Ile Glu Phe His Leu Gly Val Asn His Ile Asp Thr Glu Glu Leu Ser 
            100                 105                 110         


Ala Gly Glu Glu His Leu Val Lys Cys Leu Arg Leu Leu Arg Arg Tyr 
        115                 120                 125             


Arg Leu Ser His Asp Cys Ile Ser Leu Cys Ile Gln Ala Gln Asn Asn 
    130                 135                 140                 


Leu Gly Ile Leu Trp Ser Glu Arg Glu Glu Ile Glu Thr Ala Gln Ala 
145                 150                 155                 160 


Tyr Leu Glu Ser Ser Glu Ala Leu Tyr Asn Gln Tyr Met Lys Glu Val 
                165                 170                 175     


Gly Ser Pro Pro Leu Asp Pro Thr Glu Arg Phe Leu Pro Glu Glu Glu 
            180                 185                 190         


Lys Leu Thr Glu Gln Glu Arg Ser Lys Arg Phe Glu Lys Val Tyr Thr 
        195                 200                 205             


His Asn Leu Tyr Tyr Leu Ala Gln Val Tyr Gln His Leu Glu Met Phe 
    210                 215                 220                 


Glu Lys Ala Ala His Tyr Cys His Ser Thr Leu Lys Arg Gln Leu Glu 
225                 230                 235                 240 


His Asn Ala Tyr His Pro Ile Glu Trp Ala Ile Asn Ala Ala Thr Leu 
                245                 250                 255     


Ser Gln Phe Tyr Ile Asn Lys Leu Cys Phe Met Glu Ala Arg His Cys 
            260                 265                 270         


Leu Ser Ala Ala Asn Val Ile Phe Gly Gln Thr Gly Lys Ile Ser Ala 
        275                 280                 285             


Thr Glu Asp Thr Pro Glu Ala Glu Gly Glu Val Pro Glu Leu Tyr His 
    290                 295                 300                 


Gln Arg Lys Gly Glu Ile Ala Arg Cys Trp Ile Lys Tyr Cys Leu Thr 
305                 310                 315                 320 


Leu Met Gln Asn Ala Gln Leu Ser Met Gln Asp Asn Ile Gly Glu Leu 
                325                 330                 335     


Asp Leu Asp Lys Gln Ser Glu Leu Arg Ala Leu Arg Lys Lys Glu Leu 
            340                 345                 350         


Asp Glu Glu Glu Ser Ile Arg Lys Lys Ala Val Gln Phe Gly Thr Gly 
        355                 360                 365             


Glu Leu Cys Asp Ala Ile Ser Ala Val Glu Glu Lys Val Ser Tyr Leu 
    370                 375                 380                 


Arg Pro Leu Asp Phe Glu Glu Ala Arg Glu Leu Phe Leu Leu Gly Gln 
385                 390                 395                 400 


His Tyr Val Phe Glu Ala Lys Glu Phe Phe Gln Ile Asp Gly Tyr Val 
                405                 410                 415     


Thr Asp His Ile Glu Val Val Gln Asp His Ser Ala Leu Phe Lys Val 
            420                 425                 430         


Leu Ala Phe Phe Glu Thr Asp Met Glu Arg Arg Cys Lys Met His Lys 
        435                 440                 445             


Arg Arg Ile Ala Met Leu Glu Pro Leu Thr Val Asp Leu Asn Pro Gln 
    450                 455                 460                 


Tyr Tyr Leu Leu Val Asn Arg Gln Ile Gln Phe Glu Ile Ala His Ala 
465                 470                 475                 480 


Tyr Tyr Asp Met Met Asp Leu Lys Val Ala Ile Ala Asp Arg Leu Arg 
                485                 490                 495     


Asp Pro Asp Ser His Ile Val Lys Lys Ile Asn Asn Leu Asn Lys Ser 
            500                 505                 510         


Ala Leu Lys Tyr Tyr Gln Leu Phe Leu Asp Ser Leu Arg Asp Pro Asn 
        515                 520                 525             


Lys Val Phe Pro Glu His Ile Gly Glu Asp Val Leu Arg Pro Ala Met 
    530                 535                 540                 


Leu Ala Lys Phe Arg Val Ala Arg Leu Tyr Gly Lys Ile Ile Thr Ala 
545                 550                 555                 560 


Asp Pro Lys Lys Glu Leu Glu Asn Leu Ala Thr Ser Leu Glu His Tyr 
                565                 570                 575     


Lys Phe Ile Val Asp Tyr Cys Glu Lys His Pro Glu Ala Ala Gln Glu 
            580                 585                 590         


Ile Glu Val Glu Leu Glu Leu Ser Lys Glu Met Val Ser Leu Leu Pro 
        595                 600                 605             


Thr Lys Met Glu Arg Phe Arg Thr Lys Met Ala Leu Thr 
    610                 615                 620     


<210>  2841
<211>  428
<212>  PRT
<213>  homo sapiens

<400>  2841

Met Gly Gly Leu Phe Ser Arg Trp Arg Thr Lys Pro Ser Thr Val Glu 
1               5                   10                  15      


Val Leu Glu Ser Ile Asp Lys Glu Ile Gln Ala Leu Glu Glu Phe Arg 
            20                  25                  30          


Glu Lys Asn Gln Arg Leu Gln Lys Leu Trp Val Gly Arg Leu Ile Leu 
        35                  40                  45              


Tyr Ser Ser Val Leu Tyr Leu Phe Thr Cys Leu Ile Val Tyr Leu Trp 
    50                  55                  60                  


Tyr Leu Pro Asp Glu Phe Thr Ala Arg Leu Ala Met Thr Leu Pro Phe 
65                  70                  75                  80  


Phe Ala Phe Pro Leu Ile Ile Trp Ser Ile Arg Thr Val Ile Ile Phe 
                85                  90                  95      


Phe Phe Ser Lys Arg Thr Glu Arg Asn Asn Glu Ala Leu Asp Asp Leu 
            100                 105                 110         


Lys Ser Gln Arg Lys Lys Ile Leu Glu Glu Val Met Glu Lys Glu Thr 
        115                 120                 125             


Tyr Lys Thr Ala Lys Leu Ile Leu Glu Arg Phe Asp Pro Asp Ser Lys 
    130                 135                 140                 


Lys Ala Lys Glu Cys Glu Pro Pro Ser Ala Gly Ala Ala Val Thr Ala 
145                 150                 155                 160 


Arg Pro Gly Gln Glu Ile Arg Gln Arg Thr Ala Ala Gln Arg Asn Leu 
                165                 170                 175     


Ser Pro Thr Pro Ala Ser Pro Asn Gln Gly Pro Pro Pro Gln Val Pro 
            180                 185                 190         


Val Ser Pro Gly Pro Pro Lys Asp Ser Ser Ala Pro Gly Gly Pro Pro 
        195                 200                 205             


Glu Arg Thr Val Thr Pro Ala Leu Ser Ser Asn Val Leu Pro Arg His 
    210                 215                 220                 


Leu Gly Ser Pro Ala Thr Ser Val Pro Gly Met Gly Leu His Pro Pro 
225                 230                 235                 240 


Gly Pro Pro Leu Ala Arg Pro Ile Leu Pro Arg Glu Arg Gly Ala Leu 
                245                 250                 255     


Asp Arg Ile Val Glu Tyr Leu Val Gly Asp Gly Pro Gln Asn Arg Tyr 
            260                 265                 270         


Ala Leu Ile Cys Gln Gln Cys Phe Ser His Asn Gly Met Ala Leu Lys 
        275                 280                 285             


Glu Glu Phe Glu Tyr Ile Ala Phe Arg Cys Ala Tyr Cys Phe Phe Leu 
    290                 295                 300                 


Asn Pro Ala Arg Lys Thr Arg Pro Gln Ala Pro Arg Leu Pro Glu Phe 
305                 310                 315                 320 


Ser Phe Glu Lys Arg Gln Val Val Glu Gly Ser Ser Ser Val Gly Pro 
                325                 330                 335     


Leu Pro Ser Gly Ser Val Leu Ser Ser Asp Asn Gln Phe Asn Glu Glu 
            340                 345                 350         


Ser Leu Glu His Asp Val Leu Asp Asp Asn Thr Glu Gln Thr Asp Asp 
        355                 360                 365             


Lys Ile Pro Ala Thr Glu Gln Thr Asn Gln Val Ile Glu Lys Ala Ser 
    370                 375                 380                 


Asp Ser Glu Glu Pro Glu Glu Lys Gln Glu Thr Glu Asn Glu Glu Ala 
385                 390                 395                 400 


Ser Val Ile Glu Thr Asn Ser Thr Val Pro Gly Ala Asp Ser Ile Pro 
                405                 410                 415     


Asp Pro Glu Leu Ser Gly Glu Ser Leu Thr Ala Glu 
            420                 425             


<210>  2842
<211>  622
<212>  PRT
<213>  homo sapiens

<400>  2842

Met Val Gln Arg Asp Met Ser Lys Ser Pro Pro Thr Ala Ala Ala Ala 
1               5                   10                  15      


Val Ala Gln Glu Ile Gln Met Glu Leu Leu Glu Asn Val Ala Pro Ala 
            20                  25                  30          


Gly Ala Leu Gly Ala Ala Ala Gln Ser Tyr Gly Lys Gly Ala Arg Arg 
        35                  40                  45              


Lys Asn Arg Phe Lys Gly Ser Asp Gly Ser Thr Ser Ser Asp Thr Thr 
    50                  55                  60                  


Ser Asn Ser Phe Val Arg Gln Gly Ser Ala Asp Ser Tyr Thr Ser Arg 
65                  70                  75                  80  


Pro Ser Asp Ser Asp Val Ser Leu Glu Glu Asp Arg Glu Ala Val Arg 
                85                  90                  95      


Arg Glu Ala Glu Arg Gln Ala Gln Ala Gln Leu Glu Lys Ala Lys Thr 
            100                 105                 110         


Lys Pro Val Ala Phe Ala Val Arg Thr Asn Val Ser Tyr Ser Ala Ala 
        115                 120                 125             


His Glu Asp Asp Val Pro Val Pro Gly Met Ala Ile Ser Phe Glu Ala 
    130                 135                 140                 


Lys Asp Phe Leu His Val Lys Glu Lys Phe Asn Asn Asp Trp Trp Ile 
145                 150                 155                 160 


Gly Arg Leu Val Lys Glu Gly Cys Glu Ile Gly Phe Ile Pro Ser Pro 
                165                 170                 175     


Val Lys Leu Glu Asn Met Arg Leu Gln His Glu Gln Arg Ala Lys Gln 
            180                 185                 190         


Gly Lys Phe Tyr Ser Ser Lys Ser Gly Gly Asn Ser Ser Ser Ser Leu 
        195                 200                 205             


Gly Asp Ile Val Pro Ser Ser Arg Lys Ser Thr Pro Pro Ser Ser Ala 
    210                 215                 220                 


Lys Gln Lys Gln Lys Ser Thr Glu His Thr Pro Pro Tyr Asp Val Val 
225                 230                 235                 240 


Pro Ser Met Arg Pro Val Val Leu Val Gly Pro Ser Leu Lys Gly Tyr 
                245                 250                 255     


Glu Val Thr Asp Met Met Gln Lys Ala Leu Phe Asp Phe Leu Lys His 
            260                 265                 270         


Arg Phe Glu Gly Arg Ile Ser Ile Thr Arg Val Thr Ala Asp Ile Ser 
        275                 280                 285             


Leu Ala Lys Arg Ser Val Leu Asn Asn Pro Ser Lys His Ala Ile Ile 
    290                 295                 300                 


Glu Arg Ser Asn Thr Arg Ser Ser Leu Ala Glu Val Gln Ser Glu Ile 
305                 310                 315                 320 


Glu Arg Ile Phe Glu Leu Ala Arg Thr Leu Gln Leu Val Val Leu Asp 
                325                 330                 335     


Ala Asp Thr Ile Asn His Pro Ala Gln Leu Ser Lys Thr Ser Leu Ala 
            340                 345                 350         


Pro Ile Ile Val Tyr Val Lys Ile Ser Ser Pro Lys Val Leu Gln Arg 
        355                 360                 365             


Leu Ile Lys Ser Arg Gly Lys Ser Gln Ala Lys His Leu Asn Val Gln 
    370                 375                 380                 


Met Val Ala Ala Asp Lys Leu Ala Gln Cys Pro Pro Glu Leu Phe Asp 
385                 390                 395                 400 


Val Ile Leu Asp Glu Asn Gln Leu Glu Asp Ala Cys Glu His Leu Ala 
                405                 410                 415     


Asp Tyr Leu Glu Ala Tyr Trp Lys Ala Thr His Pro Pro Ser Ser Ser 
            420                 425                 430         


Leu Pro Asn Pro Leu Leu Ser Arg Thr Leu Ala Thr Ser Ser Leu Pro 
        435                 440                 445             


Leu Ser Pro Thr Leu Ala Ser Asn Ser Gln Gly Ser Gln Gly Asp Gln 
    450                 455                 460                 


Arg Thr Asp Arg Ser Ala Pro Ile Arg Ser Ala Ser Gln Ala Glu Glu 
465                 470                 475                 480 


Glu Pro Ser Val Glu Pro Val Lys Lys Ser Gln His Arg Ser Ser Ser 
                485                 490                 495     


Ser Ala Pro His His Asn His Arg Ser Gly Thr Ser Arg Gly Leu Ser 
            500                 505                 510         


Arg Gln Glu Thr Phe Asp Ser Glu Thr Gln Glu Ser Arg Asp Ser Ala 
        515                 520                 525             


Tyr Val Glu Pro Lys Glu Asp Tyr Ser His Asp His Val Asp His Tyr 
    530                 535                 540                 


Ala Ser His Arg Asp His Asn His Arg Asp Glu Thr His Gly Ser Ser 
545                 550                 555                 560 


Asp His Arg His Arg Glu Ser Arg His Arg Ser Arg Asp Val Asp Arg 
                565                 570                 575     


Glu Gln Asp His Asn Glu Cys Asn Lys Gln Arg Ser Arg His Lys Ser 
            580                 585                 590         


Lys Asp Arg Tyr Cys Glu Lys Asp Gly Glu Val Ile Ser Lys Lys Arg 
        595                 600                 605             


Asn Glu Ala Gly Glu Trp Asn Arg Asp Val Tyr Ile Arg Gln 
    610                 615                 620         


<210>  2843
<211>  136
<212>  PRT
<213>  homo sapiens

<400>  2843

Met Asn Ser Lys Gly Gln Tyr Pro Thr Gln Pro Thr Tyr Pro Val Gln 
1               5                   10                  15      


Pro Pro Gly Asn Pro Val Tyr Pro Gln Thr Leu His Leu Pro Gln Ala 
            20                  25                  30          


Pro Pro Tyr Thr Asp Ala Pro Pro Ala Tyr Ser Glu Ser Val Ala Val 
        35                  40                  45              


Gly Pro Leu Gly Ser Thr Ile Pro Met Ala Tyr Tyr Pro Val Gly Pro 
    50                  55                  60                  


Ile Tyr Pro Pro Gly Ser Thr Val Leu Val Glu Gly Gly Tyr Asp Ala 
65                  70                  75                  80  


Gly Ala Arg Phe Gly Ala Gly Ala Thr Ala Gly Asn Ile Pro Pro Pro 
                85                  90                  95      


Pro Pro Gly Cys Pro Pro Asn Ala Ala Gln Leu Ala Val Met Gln Gly 
            100                 105                 110         


Ala Asn Val Leu Val Thr Gln Arg Lys Gly Asn Phe Phe Met Gly Gly 
        115                 120                 125             


Ser Asp Gly Gly Tyr Thr Ile Trp 
    130                 135     


<210>  2844
<211>  1580
<212>  PRT
<213>  homo sapiens

<400>  2844

Met Glu Ala Gln Ser His Ser Ser Thr Thr Thr Glu Lys Lys Lys Val 
1               5                   10                  15      


Glu Asn Ser Ile Val Lys Cys Ser Thr Arg Thr Asp Val Ser Glu Lys 
            20                  25                  30          


Ala Val Ala Ser Ser Thr Thr Ser Asn Glu Asp Glu Ser Pro Gly Gln 
        35                  40                  45              


Thr Tyr His Arg Glu Arg Arg Asn Ala Ile Thr Met Gln Pro Gln Asn 
    50                  55                  60                  


Val Gln Gly Leu Ser Lys Val Ser Glu Glu Pro Ser Thr Ser Ser Asp 
65                  70                  75                  80  


Glu Arg Ala Ser Leu Ile Lys Lys Glu Ile His Gly Ser Leu Pro His 
                85                  90                  95      


Val Ala Glu Pro Ser Val Pro Tyr Arg Gly Thr Val Phe Ala Met Asp 
            100                 105                 110         


Pro Arg Asn Gly Tyr Met Glu Pro His Tyr His Pro Pro His Leu Phe 
        115                 120                 125             


Pro Ala Phe His Pro Pro Val Pro Ile Asp Ala Arg His His Glu Gly 
    130                 135                 140                 


Arg Tyr His Tyr Asp Pro Ser Pro Ile Pro Pro Leu His Met Thr Ser 
145                 150                 155                 160 


Ala Leu Ser Ser Ser Pro Thr Tyr Pro Asp Leu Pro Phe Ile Arg Ile 
                165                 170                 175     


Ser Pro His Arg Asn Pro Thr Ala Ala Ser Glu Ser Pro Phe Ser Pro 
            180                 185                 190         


Pro His Pro Tyr Ile Asn Pro Tyr Met Asp Tyr Ile Arg Ser Leu His 
        195                 200                 205             


Ser Ser Pro Ser Leu Ser Met Ile Ser Ala Thr Arg Gly Leu Ser Pro 
    210                 215                 220                 


Thr Asp Ala Pro His Ala Gly Val Ser Pro Ala Glu Tyr Tyr His Gln 
225                 230                 235                 240 


Met Ala Leu Leu Thr Gly Gln Arg Ser Pro Tyr Ala Asp Ile Ile Pro 
                245                 250                 255     


Ser Ala Ala Thr Ala Gly Thr Gly Ala Ile His Met Glu Tyr Leu His 
            260                 265                 270         


Ala Met Asp Ser Thr Arg Phe Ser Ser Pro Arg Leu Ser Ala Arg Pro 
        275                 280                 285             


Ser Arg Lys Arg Thr Leu Ser Ile Ser Pro Leu Ser Asp His Ser Phe 
    290                 295                 300                 


Asp Leu Gln Thr Met Ile Arg Thr Ser Pro Asn Ser Leu Val Thr Ile 
305                 310                 315                 320 


Leu Asn Asn Ser Arg Ser Ser Ser Ser Ala Ser Gly Ser Tyr Gly His 
                325                 330                 335     


Leu Ser Ala Ser Ala Ile Ser Pro Ala Leu Ser Phe Thr Tyr Ser Ser 
            340                 345                 350         


Ala Pro Val Ser Leu His Met His Gln Gln Ile Leu Ser Arg Gln Gln 
        355                 360                 365             


Ser Leu Gly Ser Ala Phe Gly His Ser Pro Pro Leu Ile His Pro Ala 
    370                 375                 380                 


Pro Thr Phe Pro Thr Gln Arg Pro Ile Pro Gly Ile Pro Thr Val Leu 
385                 390                 395                 400 


Asn Pro Val Gln Val Ser Ser Gly Pro Ser Glu Ser Ser Gln Asn Lys 
                405                 410                 415     


Pro Thr Ser Glu Ser Ala Val Ser Ser Thr Gly Asp Pro Met His Asn 
            420                 425                 430         


Lys Arg Ser Lys Ile Lys Pro Asp Glu Asp Leu Pro Ser Pro Gly Ala 
        435                 440                 445             


Arg Gly Gln Gln Glu Gln Pro Glu Gly Thr Thr Leu Val Lys Glu Glu 
    450                 455                 460                 


Gly Asp Lys Asp Glu Ser Lys Gln Glu Pro Glu Val Ile Tyr Glu Thr 
465                 470                 475                 480 


Asn Cys His Trp Glu Gly Cys Ala Arg Glu Phe Asp Thr Gln Glu Gln 
                485                 490                 495     


Leu Val His His Ile Asn Asn Asp His Ile His Gly Glu Lys Lys Glu 
            500                 505                 510         


Phe Val Cys Arg Trp Leu Asp Cys Ser Arg Glu Gln Lys Pro Phe Lys 
        515                 520                 525             


Ala Gln Tyr Met Leu Val Val His Met Arg Arg His Thr Gly Glu Lys 
    530                 535                 540                 


Pro His Lys Cys Thr Phe Glu Gly Cys Thr Lys Ala Tyr Ser Arg Leu 
545                 550                 555                 560 


Glu Asn Leu Lys Thr His Leu Arg Ser His Thr Gly Glu Lys Pro Tyr 
                565                 570                 575     


Val Cys Glu His Glu Gly Cys Asn Lys Ala Phe Ser Asn Ala Ser Asp 
            580                 585                 590         


Arg Ala Lys His Gln Asn Arg Thr His Ser Asn Glu Lys Pro Tyr Val 
        595                 600                 605             


Cys Lys Ile Pro Gly Cys Thr Lys Arg Tyr Thr Asp Pro Ser Ser Leu 
    610                 615                 620                 


Arg Lys His Val Lys Thr Val His Gly Pro Glu Ala His Val Thr Lys 
625                 630                 635                 640 


Lys Gln Arg Gly Asp Ile His Pro Arg Pro Pro Pro Pro Arg Asp Ser 
                645                 650                 655     


Gly Ser His Ser Gln Ser Arg Ser Pro Gly Arg Pro Thr Gln Gly Ala 
            660                 665                 670         


Leu Gly Glu Gln Gln Asp Leu Ser Asn Thr Thr Ser Lys Arg Glu Glu 
        675                 680                 685             


Cys Leu Gln Val Lys Thr Val Lys Ala Glu Lys Pro Met Thr Ser Gln 
    690                 695                 700                 


Pro Ser Pro Gly Gly Gln Ser Ser Cys Ser Ser Gln Gln Ser Pro Ile 
705                 710                 715                 720 


Ser Asn Tyr Ser Asn Ser Gly Leu Glu Leu Pro Leu Thr Asp Gly Gly 
                725                 730                 735     


Ser Ile Gly Asp Leu Ser Ala Ile Asp Glu Thr Pro Ile Met Asp Ser 
            740                 745                 750         


Thr Ile Ser Thr Ala Thr Thr Ala Leu Ala Leu Gln Ala Arg Arg Asn 
        755                 760                 765             


Pro Ala Gly Thr Lys Trp Met Glu His Val Lys Leu Glu Arg Leu Lys 
    770                 775                 780                 


Gln Val Asn Gly Met Phe Pro Arg Leu Asn Pro Ile Leu Pro Pro Lys 
785                 790                 795                 800 


Ala Pro Ala Val Ser Pro Leu Ile Gly Asn Gly Thr Gln Ser Asn Asn 
                805                 810                 815     


Thr Cys Ser Leu Gly Gly Pro Met Thr Leu Leu Pro Gly Arg Ser Asp 
            820                 825                 830         


Leu Ser Gly Val Asp Val Thr Met Leu Asn Met Leu Asn Arg Arg Asp 
        835                 840                 845             


Ser Ser Ala Ser Thr Ile Ser Ser Ala Tyr Leu Ser Ser Arg Arg Ser 
    850                 855                 860                 


Ser Gly Ile Ser Pro Cys Phe Ser Ser Arg Arg Ser Ser Glu Ala Ser 
865                 870                 875                 880 


Gln Ala Glu Gly Arg Pro Gln Asn Val Ser Val Ala Asp Ser Tyr Asp 
                885                 890                 895     


Pro Ile Ser Thr Asp Ala Ser Arg Arg Ser Ser Glu Ala Ser Gln Ser 
            900                 905                 910         


Asp Gly Leu Pro Ser Leu Leu Ser Leu Thr Pro Ala Gln Gln Tyr Arg 
        915                 920                 925             


Leu Lys Ala Lys Tyr Ala Ala Ala Thr Gly Gly Pro Pro Pro Thr Pro 
    930                 935                 940                 


Leu Pro Asn Met Glu Arg Met Ser Leu Lys Thr Arg Leu Ala Leu Leu 
945                 950                 955                 960 


Gly Asp Ala Leu Glu Pro Gly Val Ala Leu Pro Pro Val His Ala Pro 
                965                 970                 975     


Arg Arg Cys Ser Asp Gly Gly Ala His Gly Tyr Gly Arg Arg His Leu 
            980                 985                 990         


Gln Pro His Asp Ala Pro Gly His  Gly Val Arg Arg Ala  Ser Asp Pro 
        995                 1000                 1005             


Val Arg  Thr Gly Ser Glu Gly  Leu Ala Leu Pro Arg  Val Pro Arg 
    1010                 1015                 1020             


Phe Ser  Ser Leu Ser Ser Cys  Asn Pro Pro Ala Met  Ala Thr Ser 
    1025                 1030                 1035             


Ala Glu  Lys Arg Ser Leu Val  Leu Gln Asn Tyr Thr  Arg Pro Glu 
    1040                 1045                 1050             


Gly Gly  Gln Ser Arg Asn Phe  His Ser Ser Pro Cys  Pro Pro Ser 
    1055                 1060                 1065             


Ile Thr  Glu Asn Val Thr Leu  Glu Ser Leu Thr Met  Asp Ala Asp 
    1070                 1075                 1080             


Ala Asn  Leu Asn Asp Glu Asp  Phe Leu Pro Asp Asp  Val Val Gln 
    1085                 1090                 1095             


Tyr Leu  Asn Ser Gln Asn Gln  Ala Gly Tyr Glu Gln  His Phe Pro 
    1100                 1105                 1110             


Ser Ala  Leu Pro Asp Asp Ser  Lys Val Pro His Gly  Pro Gly Asp 
    1115                 1120                 1125             


Phe Asp  Ala Pro Gly Leu Pro  Asp Ser His Ala Gly  Gln Gln Phe 
    1130                 1135                 1140             


His Ala  Leu Glu Gln Pro Cys  Pro Glu Gly Ser Lys  Thr Asp Leu 
    1145                 1150                 1155             


Pro Ile  Gln Trp Asn Glu Val  Ser Ser Gly Ser Ala  Asp Leu Ser 
    1160                 1165                 1170             


Ser Ser  Lys Leu Lys Cys Gly  Pro Arg Pro Ala Val  Pro Gln Thr 
    1175                 1180                 1185             


Arg Ala  Phe Gly Phe Cys Asn  Gly Met Val Val His  Pro Gln Asn 
    1190                 1195                 1200             


Pro Leu  Arg Ser Gly Pro Ala  Gly Gly Tyr Gln Thr  Leu Gly Glu 
    1205                 1210                 1215             


Asn Ser  Asn Pro Tyr Gly Gly  Pro Glu His Leu Met  Leu His Asn 
    1220                 1225                 1230             


Ser Pro  Gly Ser Gly Thr Ser  Gly Asn Ala Phe His  Glu Gln Pro 
    1235                 1240                 1245             


Cys Lys  Ala Pro Gln Tyr Gly  Asn Cys Leu Asn Arg  Gln Pro Val 
    1250                 1255                 1260             


Ala Pro  Gly Ala Leu Asp Gly  Ala Cys Gly Ala Gly  Ile Gln Ala 
    1265                 1270                 1275             


Ser Lys  Leu Lys Ser Thr Pro  Met Gln Gly Ser Gly  Gly Gln Leu 
    1280                 1285                 1290             


Asn Phe  Gly Leu Pro Val Ala  Pro Asn Glu Ser Ala  Gly Ser Met 
    1295                 1300                 1305             


Val Asn  Gly Met Gln Asn Gln  Asp Pro Val Gly Gln  Gly Tyr Leu 
    1310                 1315                 1320             


Ala His  Gln Leu Leu Gly Asp  Ser Met Gln His Pro  Gly Ala Gly 
    1325                 1330                 1335             


Arg Pro  Gly Gln Gln Met Leu  Gly Gln Ile Ser Ala  Thr Ser His 
    1340                 1345                 1350             


Ile Asn  Ile Tyr Gln Gly Pro  Glu Ser Cys Leu Pro  Gly Ala His 
    1355                 1360                 1365             


Gly Met  Gly Ser Gln Pro Ser  Ser Leu Ala Val Val  Arg Gly Tyr 
    1370                 1375                 1380             


Gln Pro  Cys Ala Ser Phe Gly  Gly Ser Arg Arg Gln  Ala Met Pro 
    1385                 1390                 1395             


Arg Asp  Ser Leu Ala Leu Gln  Ser Gly Gln Leu Ser  Asp Thr Ser 
    1400                 1405                 1410             


Gln Thr  Cys Arg Val Asn Gly  Ile Lys Met Glu Met  Lys Gly Gln 
    1415                 1420                 1425             


Pro His  Pro Leu Cys Ser Asn  Leu Gln Asn Tyr Ser  Gly Gln Phe 
    1430                 1435                 1440             


Tyr Asp  Gln Thr Val Gly Phe  Ser Gln Gln Asp Thr  Lys Ala Gly 
    1445                 1450                 1455             


Ser Phe  Ser Ile Ser Asp Ala  Ser Cys Leu Leu Gln  Gly Thr Ser 
    1460                 1465                 1470             


Ala Lys  Asn Ser Glu Leu Leu  Ser Pro Gly Ala Asn  Gln Val Thr 
    1475                 1480                 1485             


Ser Thr  Val Asp Ser Leu Asp  Ser His Asp Leu Glu  Gly Val Gln 
    1490                 1495                 1500             


Ile Asp  Phe Asp Ala Ile Ile  Asp Asp Gly Asp His  Ser Ser Leu 
    1505                 1510                 1515             


Met Ser  Gly Ala Leu Ser Pro  Ser Ile Ile Gln Asn  Leu Ser His 
    1520                 1525                 1530             


Ser Ser  Ser Arg Leu Thr Thr  Pro Arg Ala Ser Leu  Pro Phe Pro 
    1535                 1540                 1545             


Ala Leu  Ser Met Ser Thr Thr  Asn Met Ala Ile Gly  Asp Met Ser 
    1550                 1555                 1560             


Ser Leu  Leu Thr Ser Leu Ala  Glu Glu Ser Lys Phe  Leu Ala Val 
    1565                 1570                 1575             


Met Gln  
    1580 


<210>  2845
<211>  142
<212>  PRT
<213>  homo sapiens

<400>  2845

Met Ile Ala Pro Thr Asp Ser His Glu Glu Val Arg Ser Gly Thr Ser 
1               5                   10                  15      


Tyr Ile Leu Pro Phe Ala Ser Arg Phe Leu Ser Phe Arg Ala Asp Ser 
            20                  25                  30          


Ala His Ala Ser Met Val Asn Val Pro Lys Thr Arg Arg Thr Phe Cys 
        35                  40                  45              


Lys Lys Cys Gly Lys His Gln Pro His Lys Val Thr Gln Tyr Lys Lys 
    50                  55                  60                  


Gly Lys Asp Ser Leu Tyr Ala Gln Gly Lys Arg Arg Tyr Asp Arg Lys 
65                  70                  75                  80  


Gln Ser Gly Tyr Gly Gly Gln Thr Lys Pro Ile Phe Arg Lys Lys Ala 
                85                  90                  95      


Lys Thr Thr Lys Lys Ile Val Leu Arg Leu Glu Cys Val Glu Pro Asn 
            100                 105                 110         


Cys Arg Ser Lys Arg Met Leu Ala Ile Lys Arg Cys Lys His Phe Glu 
        115                 120                 125             


Leu Gly Gly Asp Lys Lys Arg Lys Gly Gln Val Ile Gln Phe 
    130                 135                 140         


<210>  2846
<211>  383
<212>  PRT
<213>  homo sapiens

<400>  2846

Met Glu Leu Glu Gly Gln Trp Trp Arg Gly Gln Leu Ala Ala Asp Ile 
1               5                   10                  15      


His Gln Ala Leu Arg Tyr Lys Glu Leu Lys Leu Pro Ser Tyr Lys Gly 
            20                  25                  30          


Gln Ser Pro Gln Leu Ser Leu Arg Arg Tyr Phe Ala Asp Leu Ile Ala 
        35                  40                  45              


Ile Val Ser Asn Arg Phe Thr Leu Cys Pro Ser Ala Arg His Leu Ala 
    50                  55                  60                  


Val Tyr Leu Leu Asp Leu Phe Met Asp Arg Tyr Asp Ile Ser Ile Gln 
65                  70                  75                  80  


Gln Leu His Leu Val Ala Leu Ser Cys Leu Leu Leu Ala Ser Lys Phe 
                85                  90                  95      


Glu Glu Lys Glu Asp Ser Val Pro Lys Leu Glu Gln Leu Asn Ser Leu 
            100                 105                 110         


Gly Cys Met Thr Asn Met Asn Leu Val Leu Thr Lys Gln Asn Leu Leu 
        115                 120                 125             


His Met Glu Leu Leu Leu Leu Glu Thr Phe Gln Trp Asn Leu Cys Leu 
    130                 135                 140                 


Pro Thr Ala Ala His Phe Ile Glu Tyr Tyr Leu Ser Glu Ala Val His 
145                 150                 155                 160 


Glu Thr Asp Leu His Asp Gly Trp Pro Met Ile Cys Leu Glu Lys Thr 
                165                 170                 175     


Lys Leu Tyr Met Ala Lys Tyr Ala Asp Tyr Phe Leu Glu Val Ser Leu 
            180                 185                 190         


Gln Asp Tyr Ala Phe Leu Asn Tyr Ala Pro Ser Leu Val Ala Ala Ala 
        195                 200                 205             


Cys Val Ala Ser Ser Arg Ile Ile Leu Arg Leu Ser Pro Thr Trp Pro 
    210                 215                 220                 


Thr Arg Leu His Arg Leu Thr Ala Tyr Ser Trp Asp Phe Leu Val Gln 
225                 230                 235                 240 


Cys Ile Glu Arg Leu Leu Ile Ala His Asp Asn Asp Val Lys Glu Ala 
                245                 250                 255     


Asn Lys Gln Arg Gly Gln Ala Gly Pro Gln Ser Ala Gln Leu Ser Val 
            260                 265                 270         


Phe Gln Thr Ala Ser Gln Pro Ser Arg Pro Val His Phe Gln Gln Pro 
        275                 280                 285             


Gln Tyr Leu His Gln Thr His Gln Thr Ser Leu Gln Tyr Arg His Pro 
    290                 295                 300                 


Thr Ser Glu Gln Pro Ser Cys Gln Gln Ile Val Ser Thr Thr His Thr 
305                 310                 315                 320 


Ser Ser Tyr Thr Leu Gln Thr Cys Pro Ala Gly Phe Gln Thr Ser Val 
                325                 330                 335     


Gln Gly Leu Gly His Met Gln Thr Gly Val Gly Met Ser Leu Ala Ile 
            340                 345                 350         


Pro Val Glu Val Lys Pro Cys Leu Ser Val Ser Tyr Asn Arg Ser Tyr 
        355                 360                 365             


Gln Ile Asn Glu His Tyr Pro Cys Ile Thr Pro Cys Phe Glu Arg 
    370                 375                 380             


<210>  2847
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  2847

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  2848
<211>  109
<212>  PRT
<213>  homo sapiens

<400>  2848

Met Ser Ala Arg Gly Glu Gly Ala Gly Gln Pro Ser Thr Ser Ala Gln 
1               5                   10                  15      


Gly Gln Pro Ala Ala Pro Ala Pro Gln Lys Arg Gly Arg Gly Arg Pro 
            20                  25                  30          


Arg Lys Gln Gln Gln Glu Pro Thr Gly Glu Pro Ser Pro Lys Arg Pro 
        35                  40                  45              


Arg Gly Arg Pro Lys Gly Ser Lys Asn Lys Ser Pro Ser Lys Ala Ala 
    50                  55                  60                  


Gln Lys Lys Ala Glu Ala Thr Gly Glu Lys Arg Pro Arg Gly Arg Pro 
65                  70                  75                  80  


Arg Lys Trp Pro Gln Gln Val Val Gln Lys Lys Pro Ala Gln Glu Glu 
                85                  90                  95      


Thr Glu Glu Thr Ser Ser Gln Glu Ser Ala Glu Glu Asp 
            100                 105                 


<210>  2849
<211>  240
<212>  PRT
<213>  homo sapiens

<400>  2849

Met Ser Arg Ser Asn Arg Gln Lys Glu Tyr Lys Cys Gly Asp Leu Val 
1               5                   10                  15      


Phe Ala Lys Met Lys Gly Tyr Pro His Trp Pro Ala Arg Ile Asp Glu 
            20                  25                  30          


Met Pro Glu Ala Ala Val Lys Ser Thr Ala Asn Lys Tyr Gln Val Phe 
        35                  40                  45              


Phe Phe Gly Thr His Glu Thr Ala Phe Leu Gly Pro Lys Asp Leu Phe 
    50                  55                  60                  


Pro Tyr Glu Glu Ser Lys Glu Lys Phe Gly Lys Pro Asn Lys Arg Lys 
65                  70                  75                  80  


Gly Phe Ser Glu Gly Leu Trp Glu Ile Glu Asn Asn Pro Thr Val Lys 
                85                  90                  95      


Ala Ser Gly Tyr Gln Ser Ser Gln Lys Lys Ser Cys Val Glu Glu Pro 
            100                 105                 110         


Glu Pro Glu Pro Glu Ala Ala Glu Gly Asp Gly Asp Lys Lys Gly Asn 
        115                 120                 125             


Ala Glu Gly Ser Ser Asp Glu Glu Gly Lys Leu Val Ile Asp Glu Pro 
    130                 135                 140                 


Ala Lys Glu Lys Asn Glu Lys Gly Ala Leu Lys Arg Arg Ala Gly Asp 
145                 150                 155                 160 


Leu Leu Glu Asp Ser Pro Lys Arg Pro Lys Glu Ala Glu Asn Pro Glu 
                165                 170                 175     


Gly Glu Glu Lys Glu Ala Ala Thr Leu Glu Val Glu Arg Pro Leu Pro 
            180                 185                 190         


Met Glu Val Glu Lys Asn Ser Thr Pro Ser Glu Pro Gly Ser Gly Arg 
        195                 200                 205             


Gly Pro Pro Gln Glu Glu Glu Glu Glu Glu Asp Glu Glu Glu Glu Ala 
    210                 215                 220                 


Thr Lys Glu Asp Ala Glu Ala Pro Gly Ile Arg Asp His Glu Ser Leu 
225                 230                 235                 240 


<210>  2850
<211>  634
<212>  PRT
<213>  homo sapiens

<400>  2850

Met Asp Asn Ala Val Asp Gly Leu Asp Lys Ala Ser Ile Ala Asn Ser 
1               5                   10                  15      


Asp Gly Pro Thr Ala Gly Ser Gln Thr Pro Pro Phe Lys Arg Lys Gly 
            20                  25                  30          


Lys Leu Ser Thr Ile Gly Lys Ile Phe Lys Pro Trp Lys Trp Arg Lys 
        35                  40                  45              


Lys Lys Thr Ser Asp Lys Phe Arg Glu Thr Ser Ala Val Leu Glu Arg 
    50                  55                  60                  


Lys Ile Ser Thr Arg Gln Ser Arg Glu Glu Leu Ile Arg Arg Gly Val 
65                  70                  75                  80  


Leu Lys Glu Leu Pro Asp Gln Asp Gly Asp Val Thr Val Asn Phe Glu 
                85                  90                  95      


Asn Ser Asn Gly His Met Ile Pro Ile Gly Glu Glu Ser Thr Arg Glu 
            100                 105                 110         


Glu Asn Val Val Lys Ser Glu Glu Gly Asn Gly Ser Val Ser Glu Lys 
        115                 120                 125             


Thr Pro Pro Leu Glu Glu Gln Ala Glu Asp Lys Lys Glu Asn Thr Glu 
    130                 135                 140                 


Asn His Ser Glu Thr Pro Ala Ala Pro Ala Leu Pro Pro Ser Ala Pro 
145                 150                 155                 160 


Pro Lys Pro Arg Pro Lys Pro Lys Pro Lys Lys Ser Pro Val Pro Pro 
                165                 170                 175     


Lys Gly Ala Thr Ala Gly Ala Ser His Lys Gly Asp Glu Val Pro Pro 
            180                 185                 190         


Ile Lys Lys Asn Thr Lys Ala Pro Gly Lys Gln Ala Pro Val Pro Pro 
        195                 200                 205             


Pro Lys Pro Ala Ser Arg Asn Thr Thr Arg Glu Ala Ala Gly Ser Ser 
    210                 215                 220                 


His Ser Lys Lys Thr Thr Gly Ser Lys Ala Ser Ala Ser Pro Ser Thr 
225                 230                 235                 240 


Ser Ser Thr Ser Ser Arg Pro Lys Ala Ser Lys Glu Thr Val Ser Ser 
                245                 250                 255     


Lys Ala Gly Thr Val Gly Thr Thr Lys Gly Lys Arg Lys Thr Asp Lys 
            260                 265                 270         


Gln Pro Ile Thr Ser His Leu Ser Ser Asp Thr Thr Thr Ser Gly Thr 
        275                 280                 285             


Ser Asp Leu Lys Gly Glu Pro Ala Glu Thr Arg Val Glu Ser Phe Lys 
    290                 295                 300                 


Leu Glu Gln Thr Val Pro Gly Ala Glu Glu Gln Asn Thr Gly Lys Phe 
305                 310                 315                 320 


Lys Ser Met Val Pro Pro Pro Pro Val Ala Pro Ala Pro Ser Pro Leu 
                325                 330                 335     


Ala Pro Pro Leu Pro Leu Glu Asp Gln Cys Ile Thr Ala Ser Asp Thr 
            340                 345                 350         


Pro Val Val Leu Val Ser Val Gly Ala Asp Leu Pro Val Ser Ala Leu 
        355                 360                 365             


Asp Pro Ser Gln Leu Leu Trp Ala Glu Glu Pro Thr Asn Arg Thr Thr 
    370                 375                 380                 


Leu Tyr Ser Gly Thr Gly Leu Ser Val Asn Arg Glu Asn Ala Lys Cys 
385                 390                 395                 400 


Phe Thr Thr Lys Glu Glu Leu Gly Lys Thr Val Pro Gln Leu Leu Thr 
                405                 410                 415     


Pro Gly Leu Met Gly Glu Ser Ser Glu Ser Phe Ser Ala Ser Glu Asp 
            420                 425                 430         


Glu Gly His Arg Glu Tyr Gln Ala Asn Asp Ser Asp Ser Asp Gly Pro 
        435                 440                 445             


Ile Leu Tyr Thr Asp Asp Glu Asp Glu Asp Glu Asp Glu Asp Gly Ser 
    450                 455                 460                 


Gly Glu Ser Ala Leu Ala Ser Lys Ile Arg Arg Arg Asp Thr Leu Ala 
465                 470                 475                 480 


Ile Lys Leu Gly Asn Arg Pro Ser Lys Lys Glu Leu Glu Asp Lys Asn 
                485                 490                 495     


Ile Leu Gln Arg Thr Ser Glu Glu Glu Arg Gln Glu Ile Arg Gln Gln 
            500                 505                 510         


Ile Gly Thr Lys Leu Val Arg Arg Leu Ser Gln Arg Pro Thr Thr Glu 
        515                 520                 525             


Glu Leu Glu Gln Arg Asn Ile Leu Lys Gln Lys Asn Glu Glu Glu Glu 
    530                 535                 540                 


Gln Glu Ala Lys Met Glu Leu Lys Arg Arg Leu Ser Arg Lys Leu Ser 
545                 550                 555                 560 


Leu Arg Pro Thr Val Ala Glu Leu Gln Ala Arg Arg Ile Leu Arg Phe 
                565                 570                 575     


Asn Glu Tyr Val Glu Val Thr Asp Ser Pro Asp Tyr Asp Arg Arg Ala 
            580                 585                 590         


Asp Lys Pro Trp Ala Arg Leu Thr Pro Ala Asp Lys Ala Ala Ile Arg 
        595                 600                 605             


Lys Glu Leu Asn Glu Phe Lys Ser Thr Glu Met Glu Val His Glu Glu 
    610                 615                 620                 


Ser Arg Gln Phe Thr Arg Phe His Arg Pro 
625                 630                 


<210>  2851
<211>  322
<212>  PRT
<213>  homo sapiens

<400>  2851

Met Pro Val Thr Val Thr Arg Thr Thr Ile Thr Thr Thr Thr Thr Ser 
1               5                   10                  15      


Ser Ser Gly Leu Gly Ser Pro Met Ile Val Gly Ser Pro Arg Ala Leu 
            20                  25                  30          


Thr Gln Pro Leu Gly Leu Leu Arg Leu Leu Gln Leu Val Ser Thr Cys 
        35                  40                  45              


Val Ala Phe Ser Leu Val Ala Ser Val Gly Ala Trp Thr Gly Ser Met 
    50                  55                  60                  


Gly Asn Trp Ser Met Phe Thr Trp Cys Phe Cys Phe Ser Val Thr Leu 
65                  70                  75                  80  


Ile Ile Leu Ile Val Glu Leu Cys Gly Leu Gln Ala Arg Phe Pro Leu 
                85                  90                  95      


Ser Trp Arg Asn Phe Pro Ile Thr Phe Ala Cys Tyr Ala Ala Leu Phe 
            100                 105                 110         


Cys Leu Ser Ala Ser Ile Ile Tyr Pro Thr Thr Tyr Val Gln Phe Leu 
        115                 120                 125             


Ser His Gly Arg Ser Arg Asp His Ala Ile Ala Ala Thr Phe Phe Ser 
    130                 135                 140                 


Cys Ile Ala Cys Val Ala Tyr Ala Thr Glu Val Ala Trp Thr Arg Ala 
145                 150                 155                 160 


Arg Pro Gly Glu Ile Thr Gly Tyr Met Ala Thr Val Pro Gly Leu Leu 
                165                 170                 175     


Lys Val Leu Glu Thr Phe Val Ala Cys Ile Ile Phe Ala Phe Ile Ser 
            180                 185                 190         


Asp Pro Asn Leu Tyr Gln His Gln Pro Ala Leu Glu Trp Cys Val Ala 
        195                 200                 205             


Val Tyr Ala Ile Cys Phe Ile Leu Ala Ala Ile Ala Ile Leu Leu Asn 
    210                 215                 220                 


Leu Gly Glu Cys Thr Asn Val Leu Pro Ile Pro Phe Pro Ser Phe Leu 
225                 230                 235                 240 


Ser Gly Leu Ala Leu Leu Ser Val Leu Leu Tyr Ala Thr Ala Leu Val 
                245                 250                 255     


Leu Trp Pro Leu Tyr Gln Phe Asp Glu Lys Tyr Gly Gly Gln Pro Arg 
            260                 265                 270         


Arg Ser Arg Asp Val Ser Cys Ser Arg Ser His Ala Tyr Tyr Val Cys 
        275                 280                 285             


Ala Trp Asp Arg Arg Leu Ala Val Ala Ile Leu Thr Ala Ile Asn Leu 
    290                 295                 300                 


Leu Ala Tyr Val Ala Asp Leu Val His Ser Ala His Leu Val Phe Val 
305                 310                 315                 320 


Lys Val 
        


<210>  2852
<211>  1914
<212>  PRT
<213>  homo sapiens

<400>  2852

Met Gly Asp Val Lys Leu Val Ala Ser Ser His Ile Ser Lys Thr Ser 
1               5                   10                  15      


Leu Ser Val Asp Pro Ser Arg Val Asp Ser Met Pro Leu Thr Glu Ala 
            20                  25                  30          


Pro Ala Phe Ile Leu Pro Pro Arg Asn Leu Cys Ile Lys Glu Gly Ala 
        35                  40                  45              


Thr Ala Lys Phe Glu Gly Arg Val Arg Gly Tyr Pro Glu Pro Gln Val 
    50                  55                  60                  


Thr Trp His Arg Asn Gly Gln Pro Ile Thr Ser Gly Gly Arg Phe Leu 
65                  70                  75                  80  


Leu Asp Cys Gly Ile Arg Gly Thr Phe Ser Leu Val Ile His Ala Val 
                85                  90                  95      


His Glu Glu Asp Arg Gly Lys Tyr Thr Cys Glu Ala Thr Asn Gly Ser 
            100                 105                 110         


Gly Ala Arg Gln Val Thr Val Glu Leu Thr Val Glu Gly Ser Phe Ala 
        115                 120                 125             


Lys Gln Leu Gly Gln Pro Val Val Ser Lys Thr Leu Gly Asp Arg Phe 
    130                 135                 140                 


Ser Ala Pro Ala Val Glu Thr Arg Pro Ser Ile Trp Gly Glu Cys Pro 
145                 150                 155                 160 


Pro Lys Phe Ala Thr Lys Leu Gly Arg Val Val Val Lys Glu Gly Gln 
                165                 170                 175     


Met Gly Arg Phe Ser Cys Lys Ile Thr Gly Arg Pro Gln Pro Gln Val 
            180                 185                 190         


Thr Trp Leu Lys Gly Asn Val Pro Leu Gln Pro Ser Ala Arg Val Ser 
        195                 200                 205             


Val Ser Glu Lys Asn Gly Met Gln Val Leu Glu Ile His Gly Val Asn 
    210                 215                 220                 


Gln Asp Asp Val Gly Val Tyr Thr Cys Leu Val Val Asn Gly Ser Gly 
225                 230                 235                 240 


Lys Ala Ser Met Ser Ala Glu Leu Ser Ile Gln Gly Leu Asp Ser Ala 
                245                 250                 255     


Asn Arg Ser Phe Val Arg Glu Thr Lys Ala Thr Asn Ser Asp Val Arg 
            260                 265                 270         


Lys Glu Val Thr Asn Val Ile Ser Lys Glu Ser Lys Leu Asp Ser Leu 
        275                 280                 285             


Glu Ala Ala Ala Lys Ser Lys Asn Cys Ser Ser Pro Gln Arg Gly Gly 
    290                 295                 300                 


Ser Pro Pro Trp Ala Ala Asn Ser Gln Pro Gln Pro Pro Arg Glu Ser 
305                 310                 315                 320 


Lys Leu Glu Ser Cys Lys Asp Ser Pro Arg Thr Ala Pro Gln Thr Pro 
                325                 330                 335     


Val Leu Gln Lys Thr Ser Ser Ser Ile Thr Leu Gln Ala Ala Arg Val 
            340                 345                 350         


Gln Pro Glu Pro Arg Ala Pro Gly Leu Gly Val Leu Ser Pro Ser Gly 
        355                 360                 365             


Glu Glu Arg Lys Arg Pro Ala Pro Pro Arg Pro Ala Thr Phe Pro Thr 
    370                 375                 380                 


Arg Gln Pro Gly Leu Gly Ser Gln Asp Val Val Ser Lys Ala Ala Asn 
385                 390                 395                 400 


Arg Arg Ile Pro Met Glu Gly Gln Arg Asp Ser Ala Phe Pro Lys Phe 
                405                 410                 415     


Glu Ser Lys Pro Gln Ser Gln Glu Val Lys Glu Asn Gln Thr Val Lys 
            420                 425                 430         


Phe Arg Cys Glu Val Ser Gly Ile Pro Lys Pro Glu Val Ala Trp Phe 
        435                 440                 445             


Leu Glu Gly Thr Pro Val Arg Arg Gln Glu Gly Ser Ile Glu Val Tyr 
    450                 455                 460                 


Glu Asp Ala Gly Ser His Tyr Leu Cys Leu Leu Lys Ala Arg Thr Arg 
465                 470                 475                 480 


Asp Ser Gly Thr Tyr Ser Cys Thr Ala Ser Asn Ala Gln Gly Gln Leu 
                485                 490                 495     


Ser Cys Ser Trp Thr Leu Gln Val Glu Arg Leu Ala Val Met Glu Val 
            500                 505                 510         


Ala Pro Ser Phe Ser Ser Val Leu Lys Asp Cys Ala Val Ile Glu Gly 
        515                 520                 525             


Gln Asp Phe Val Leu Gln Cys Ser Val Arg Gly Thr Pro Val Pro Arg 
    530                 535                 540                 


Ile Thr Trp Leu Leu Asn Gly Gln Pro Ile Gln Tyr Ala Arg Ser Thr 
545                 550                 555                 560 


Cys Glu Ala Gly Val Ala Glu Leu His Ile Gln Asp Ala Leu Pro Glu 
                565                 570                 575     


Asp His Gly Thr Tyr Thr Cys Leu Ala Glu Asn Ala Leu Gly Gln Val 
            580                 585                 590         


Ser Cys Ser Ala Trp Val Thr Val His Glu Lys Lys Ser Ser Arg Lys 
        595                 600                 605             


Ser Glu Tyr Leu Leu Pro Val Ala Pro Ser Lys Pro Thr Ala Pro Ile 
    610                 615                 620                 


Phe Leu Gln Gly Leu Ser Asp Leu Lys Val Met Asp Gly Ser Gln Val 
625                 630                 635                 640 


Thr Met Thr Val Gln Val Ser Gly Asn Pro Pro Pro Glu Val Ile Trp 
                645                 650                 655     


Leu His Asn Gly Asn Glu Ile Gln Glu Ser Glu Asp Phe His Phe Glu 
            660                 665                 670         


Gln Arg Gly Thr Gln His Ser Leu Cys Ile Gln Glu Val Phe Pro Glu 
        675                 680                 685             


Asp Thr Gly Thr Tyr Thr Cys Glu Ala Trp Asn Ser Ala Gly Glu Val 
    690                 695                 700                 


Arg Thr Gln Ala Val Leu Thr Val Gln Glu Pro His Asp Gly Thr Gln 
705                 710                 715                 720 


Pro Trp Phe Ile Ser Lys Pro Arg Ser Val Thr Ala Ser Leu Gly Gln 
                725                 730                 735     


Ser Val Leu Ile Ser Cys Ala Ile Ala Gly Asp Pro Phe Pro Thr Val 
            740                 745                 750         


His Trp Leu Arg Asp Gly Lys Ala Leu Cys Lys Asp Thr Gly His Phe 
        755                 760                 765             


Glu Val Leu Gln Asn Glu Asp Val Phe Thr Leu Val Leu Lys Lys Val 
    770                 775                 780                 


Gln Pro Trp His Ala Gly Gln Tyr Glu Ile Leu Leu Lys Asn Arg Val 
785                 790                 795                 800 


Gly Glu Cys Ser Cys Gln Val Ser Leu Met Leu Gln Asn Ser Ser Ala 
                805                 810                 815     


Arg Ala Leu Pro Arg Gly Arg Glu Pro Ala Ser Cys Glu Asp Leu Cys 
            820                 825                 830         


Gly Gly Gly Val Gly Ala Asp Gly Gly Gly Ser Asp Arg Tyr Gly Ser 
        835                 840                 845             


Leu Arg Pro Gly Trp Pro Ala Arg Gly Gln Gly Trp Leu Glu Glu Glu 
    850                 855                 860                 


Asp Gly Glu Asp Val Arg Gly Val Leu Lys Arg Arg Val Glu Thr Arg 
865                 870                 875                 880 


Gln His Thr Glu Glu Ala Ile Arg Gln Gln Glu Val Glu Gln Leu Asp 
                885                 890                 895     


Phe Arg Asp Leu Leu Gly Lys Lys Val Ser Thr Lys Thr Leu Ser Glu 
            900                 905                 910         


Asp Asp Leu Lys Glu Ile Pro Ala Glu Gln Met Asp Phe Arg Ala Asn 
        915                 920                 925             


Leu Gln Arg Gln Val Lys Pro Lys Thr Val Ser Glu Glu Glu Arg Lys 
    930                 935                 940                 


Val His Ser Pro Gln Gln Val Asp Phe Arg Ser Val Leu Ala Lys Lys 
945                 950                 955                 960 


Gly Thr Ser Lys Thr Pro Val Pro Glu Lys Val Pro Pro Pro Lys Pro 
                965                 970                 975     


Ala Thr Pro Asp Phe Arg Ser Val Leu Gly Gly Lys Lys Lys Leu Pro 
            980                 985                 990         


Ala Glu Asn Gly Ser Ser Ser Ala  Glu Thr Leu Asn Ala  Lys Ala Val 
        995                 1000                 1005             


Glu Ser  Ser Lys Pro Leu Ser  Asn Ala Gln Pro Ser  Gly Pro Leu 
    1010                 1015                 1020             


Lys Pro  Val Gly Asn Ala Lys  Pro Ala Glu Thr Leu  Lys Pro Met 
    1025                 1030                 1035             


Gly Asn  Ala Lys Pro Ala Glu  Thr Leu Lys Pro Met  Gly Asn Ala 
    1040                 1045                 1050             


Lys Pro  Asp Glu Asn Leu Lys  Ser Ala Ser Lys Glu  Glu Leu Lys 
    1055                 1060                 1065             


Lys Asp  Val Lys Asn Asp Val  Asn Cys Lys Arg Gly  His Ala Gly 
    1070                 1075                 1080             


Thr Thr  Asp Asn Glu Lys Arg  Ser Glu Ser Gln Gly  Thr Ala Pro 
    1085                 1090                 1095             


Ala Phe  Lys Gln Lys Leu Gln  Asp Val His Val Ala  Glu Gly Lys 
    1100                 1105                 1110             


Lys Leu  Leu Leu Gln Cys Gln  Val Ser Ser Asp Pro  Pro Ala Thr 
    1115                 1120                 1125             


Ile Ile  Trp Thr Leu Asn Gly  Lys Thr Leu Lys Thr  Thr Lys Phe 
    1130                 1135                 1140             


Ile Ile  Leu Ser Gln Glu Gly  Ser Leu Cys Ser Val  Ser Ile Glu 
    1145                 1150                 1155             


Lys Ala  Leu Pro Glu Asp Arg  Gly Leu Tyr Lys Cys  Val Ala Lys 
    1160                 1165                 1170             


Asn Asp  Ala Gly Gln Ala Glu  Cys Ser Cys Gln Val  Thr Val Asp 
    1175                 1180                 1185             


Asp Ala  Pro Ala Ser Glu Asn  Thr Lys Ala Pro Glu  Met Lys Ser 
    1190                 1195                 1200             


Arg Arg  Pro Lys Ser Ser Leu  Pro Pro Val Leu Gly  Thr Glu Ser 
    1205                 1210                 1215             


Asp Ala  Thr Val Lys Lys Lys  Pro Ala Pro Lys Thr  Pro Pro Lys 
    1220                 1225                 1230             


Ala Ala  Met Pro Pro Gln Ile  Ile Gln Phe Pro Glu  Asp Gln Lys 
    1235                 1240                 1245             


Val Arg  Ala Gly Glu Ser Val  Glu Leu Phe Gly Lys  Val Thr Gly 
    1250                 1255                 1260             


Thr Gln  Pro Ile Thr Cys Thr  Trp Met Lys Phe Arg  Lys Gln Ile 
    1265                 1270                 1275             


Gln Glu  Ser Glu His Met Lys  Val Glu Asn Ser Glu  Asn Gly Ser 
    1280                 1285                 1290             


Lys Leu  Thr Ile Leu Ala Ala  Arg Gln Glu His Cys  Gly Cys Tyr 
    1295                 1300                 1305             


Thr Leu  Leu Val Glu Asn Lys  Leu Gly Ser Arg Gln  Ala Gln Val 
    1310                 1315                 1320             


Asn Leu  Thr Val Val Asp Lys  Pro Asp Pro Pro Ala  Gly Thr Pro 
    1325                 1330                 1335             


Cys Ala  Ser Asp Ile Arg Ser  Ser Ser Leu Thr Leu  Ser Trp Tyr 
    1340                 1345                 1350             


Gly Ser  Ser Tyr Asp Gly Gly  Ser Ala Val Gln Ser  Tyr Ser Ile 
    1355                 1360                 1365             


Glu Ile  Trp Asp Ser Ala Asn  Lys Thr Trp Lys Glu  Leu Ala Thr 
    1370                 1375                 1380             


Cys Arg  Ser Thr Ser Phe Asn  Val Gln Asp Leu Leu  Pro Asp His 
    1385                 1390                 1395             


Glu Tyr  Lys Phe Arg Val Arg  Ala Ile Asn Val Tyr  Gly Thr Ser 
    1400                 1405                 1410             


Glu Pro  Ser Gln Glu Ser Glu  Leu Thr Thr Val Gly  Glu Lys Pro 
    1415                 1420                 1425             


Glu Glu  Pro Lys Asp Glu Val  Glu Val Ser Asp Asp  Asp Glu Lys 
    1430                 1435                 1440             


Glu Pro  Glu Val Asp Tyr Arg  Thr Val Thr Ile Asn  Thr Glu Gln 
    1445                 1450                 1455             


Lys Val  Ser Asp Phe Tyr Asp  Ile Glu Glu Arg Leu  Gly Ser Gly 
    1460                 1465                 1470             


Lys Phe  Gly Gln Val Phe Arg  Leu Val Glu Lys Lys  Thr Arg Lys 
    1475                 1480                 1485             


Val Trp  Ala Gly Lys Phe Phe  Lys Ala Tyr Ser Ala  Lys Glu Lys 
    1490                 1495                 1500             


Glu Asn  Ile Arg Gln Glu Ile  Ser Ile Met Asn Cys  Leu His His 
    1505                 1510                 1515             


Pro Lys  Leu Val Gln Cys Val  Asp Ala Phe Glu Glu  Lys Ala Asn 
    1520                 1525                 1530             


Ile Val  Met Val Leu Glu Ile  Val Ser Gly Gly Glu  Leu Phe Glu 
    1535                 1540                 1545             


Arg Ile  Ile Asp Glu Asp Phe  Glu Leu Thr Glu Arg  Glu Cys Ile 
    1550                 1555                 1560             


Lys Tyr  Met Arg Gln Ile Ser  Glu Gly Val Glu Tyr  Ile His Lys 
    1565                 1570                 1575             


Gln Gly  Ile Val His Leu Asp  Leu Lys Pro Glu Asn  Ile Met Cys 
    1580                 1585                 1590             


Val Asn  Lys Thr Gly Thr Arg  Ile Lys Leu Ile Asp  Phe Gly Leu 
    1595                 1600                 1605             


Ala Arg  Arg Leu Glu Asn Ala  Gly Ser Leu Lys Val  Leu Phe Gly 
    1610                 1615                 1620             


Thr Pro  Glu Phe Val Ala Pro  Glu Val Ile Asn Tyr  Glu Pro Ile 
    1625                 1630                 1635             


Gly Tyr  Ala Thr Asp Met Trp  Ser Ile Gly Val Ile  Cys Tyr Ile 
    1640                 1645                 1650             


Leu Val  Ser Gly Leu Ser Pro  Phe Met Gly Asp Asn  Asp Asn Glu 
    1655                 1660                 1665             


Thr Leu  Ala Asn Val Thr Ser  Ala Thr Trp Asp Phe  Asp Asp Glu 
    1670                 1675                 1680             


Ala Phe  Asp Glu Ile Ser Asp  Asp Ala Lys Asp Phe  Ile Ser Asn 
    1685                 1690                 1695             


Leu Leu  Lys Lys Asp Met Lys  Asn Arg Leu Asp Cys  Thr Gln Cys 
    1700                 1705                 1710             


Leu Gln  His Pro Trp Leu Met  Lys Asp Thr Lys Asn  Met Glu Ala 
    1715                 1720                 1725             


Lys Lys  Leu Ser Lys Asp Arg  Met Lys Lys Tyr Met  Ala Arg Arg 
    1730                 1735                 1740             


Lys Trp  Gln Lys Thr Gly Asn  Ala Val Arg Ala Ile  Gly Arg Leu 
    1745                 1750                 1755             


Ser Ser  Met Ala Met Ile Ser  Gly Leu Ser Gly Arg  Lys Ser Ser 
    1760                 1765                 1770             


Thr Gly  Ser Pro Thr Ser Pro  Leu Asn Ala Glu Lys  Leu Glu Ser 
    1775                 1780                 1785             


Glu Glu  Asp Val Ser Gln Ala  Phe Leu Glu Ala Val  Ala Glu Glu 
    1790                 1795                 1800             


Lys Pro  His Val Lys Pro Tyr  Phe Ser Lys Thr Ile  Arg Asp Leu 
    1805                 1810                 1815             


Glu Val  Val Glu Gly Ser Ala  Ala Arg Phe Asp Cys  Lys Ile Glu 
    1820                 1825                 1830             


Gly Tyr  Pro Asp Pro Glu Val  Val Trp Phe Lys Asp  Asp Gln Ser 
    1835                 1840                 1845             


Ile Arg  Glu Ser Arg His Phe  Gln Ile Asp Tyr Asp  Glu Asp Gly 
    1850                 1855                 1860             


Asn Cys  Ser Leu Ile Ile Ser  Asp Val Cys Gly Asp  Asp Asp Ala 
    1865                 1870                 1875             


Lys Tyr  Thr Cys Lys Ala Val  Asn Ser Leu Gly Glu  Ala Thr Cys 
    1880                 1885                 1890             


Thr Ala  Glu Leu Ile Val Glu  Thr Met Glu Glu Gly  Glu Gly Glu 
    1895                 1900                 1905             


Gly Glu  Glu Glu Glu Glu 
    1910                 


<210>  2853
<211>  599
<212>  PRT
<213>  homo sapiens

<400>  2853

Met Ala Asp Lys Leu Thr Arg Ile Ala Ile Val Asn His Asp Lys Cys 
1               5                   10                  15      


Lys Pro Lys Lys Cys Arg Gln Glu Cys Lys Lys Ser Cys Pro Val Val 
            20                  25                  30          


Arg Met Gly Lys Leu Cys Ile Glu Val Thr Pro Gln Ser Lys Ile Ala 
        35                  40                  45              


Trp Ile Ser Glu Thr Leu Cys Ile Gly Cys Gly Ile Cys Ile Lys Lys 
    50                  55                  60                  


Cys Pro Phe Gly Ala Leu Ser Ile Val Asn Leu Pro Ser Asn Leu Glu 
65                  70                  75                  80  


Lys Glu Thr Thr His Arg Tyr Cys Ala Asn Ala Phe Lys Leu His Arg 
                85                  90                  95      


Leu Pro Ile Pro Arg Pro Gly Glu Val Leu Gly Leu Val Gly Thr Asn 
            100                 105                 110         


Gly Ile Gly Lys Ser Thr Ala Leu Lys Ile Leu Ala Gly Lys Gln Lys 
        115                 120                 125             


Pro Asn Leu Gly Lys Tyr Asp Asp Pro Pro Asp Trp Gln Glu Ile Leu 
    130                 135                 140                 


Thr Tyr Phe Arg Gly Ser Glu Leu Gln Asn Tyr Phe Thr Lys Ile Leu 
145                 150                 155                 160 


Glu Asp Asp Leu Lys Ala Ile Ile Lys Pro Gln Tyr Val Asp Gln Ile 
                165                 170                 175     


Pro Lys Ala Ala Lys Gly Thr Val Gly Ser Ile Leu Asp Arg Lys Asp 
            180                 185                 190         


Glu Thr Lys Thr Gln Ala Ile Val Cys Gln Gln Leu Asp Leu Thr His 
        195                 200                 205             


Leu Lys Glu Arg Asn Val Glu Asp Leu Ser Gly Gly Glu Leu Gln Arg 
    210                 215                 220                 


Phe Ala Cys Ala Val Val Cys Ile Gln Lys Ala Asp Ile Phe Met Phe 
225                 230                 235                 240 


Asp Glu Pro Ser Ser Tyr Leu Asp Val Lys Gln Arg Leu Lys Ala Ala 
                245                 250                 255     


Ile Thr Ile Arg Ser Leu Ile Asn Pro Asp Arg Tyr Ile Ile Val Val 
            260                 265                 270         


Glu His Asp Leu Ser Val Leu Asp Tyr Leu Ser Asp Phe Ile Cys Cys 
        275                 280                 285             


Leu Tyr Gly Val Pro Ser Ala Tyr Gly Val Val Thr Met Pro Phe Ser 
    290                 295                 300                 


Val Arg Glu Gly Ile Asn Ile Phe Leu Asp Gly Tyr Val Pro Thr Glu 
305                 310                 315                 320 


Asn Leu Arg Phe Arg Asp Ala Ser Leu Val Phe Lys Val Ala Glu Thr 
                325                 330                 335     


Ala Asn Glu Glu Glu Val Lys Lys Met Cys Met Tyr Lys Tyr Pro Gly 
            340                 345                 350         


Met Lys Lys Lys Met Gly Glu Phe Glu Leu Ala Ile Val Ala Gly Glu 
        355                 360                 365             


Phe Thr Asp Ser Glu Ile Met Val Met Leu Gly Glu Asn Gly Thr Gly 
    370                 375                 380                 


Lys Thr Thr Phe Ile Arg Met Leu Ala Gly Arg Leu Lys Pro Asp Glu 
385                 390                 395                 400 


Gly Gly Glu Val Pro Val Leu Asn Val Ser Tyr Lys Pro Gln Lys Ile 
                405                 410                 415     


Ser Pro Lys Ser Thr Gly Ser Val Arg Gln Leu Leu His Glu Lys Ile 
            420                 425                 430         


Arg Asp Ala Tyr Thr His Pro Gln Phe Val Thr Asp Val Met Lys Pro 
        435                 440                 445             


Leu Gln Ile Glu Asn Ile Ile Asp Gln Glu Val Gln Thr Leu Ser Gly 
    450                 455                 460                 


Gly Glu Leu Gln Arg Val Ala Leu Ala Leu Cys Leu Gly Lys Pro Ala 
465                 470                 475                 480 


Asp Val Tyr Leu Ile Asp Glu Pro Ser Ala Tyr Leu Asp Ser Glu Gln 
                485                 490                 495     


Arg Leu Met Ala Ala Arg Val Val Lys Arg Phe Ile Leu His Ala Lys 
            500                 505                 510         


Lys Thr Ala Phe Val Val Glu His Asp Phe Ile Met Ala Thr Tyr Leu 
        515                 520                 525             


Ala Asp Arg Val Ile Val Phe Asp Gly Val Pro Ser Lys Asn Thr Val 
    530                 535                 540                 


Ala Asn Ser Pro Gln Thr Leu Leu Ala Gly Met Asn Lys Phe Leu Ser 
545                 550                 555                 560 


Gln Leu Glu Ile Thr Phe Arg Arg Asp Pro Asn Asn Tyr Arg Pro Arg 
                565                 570                 575     


Ile Asn Lys Leu Asn Ser Ile Lys Asp Val Glu Gln Lys Lys Ser Gly 
            580                 585                 590         


Asn Tyr Phe Phe Leu Asp Asp 
        595                 


<210>  2854
<211>  533
<212>  PRT
<213>  homo sapiens

<400>  2854

Met Ala Thr Ser Leu His Glu Gly Pro Thr Asn Gln Leu Asp Leu Leu 
1               5                   10                  15      


Ile Arg Ala Val Glu Ala Ser Val His Ser Ser Asn Ala His Cys Thr 
            20                  25                  30          


Asp Lys Thr Ile Glu Ala Ala Glu Ala Leu Leu His Met Glu Ser Pro 
        35                  40                  45              


Thr Cys Leu Arg Asp Ser Arg Ser Pro Val Glu Val Phe Val Pro Pro 
    50                  55                  60                  


Cys Val Ser Thr Pro Glu Phe Ile His Ala Ala Met Arg Pro Asp Val 
65                  70                  75                  80  


Ile Thr Glu Thr Val Val Glu Val Ser Thr Glu Glu Ser Glu Pro Met 
                85                  90                  95      


Asp Thr Ser Pro Ile Pro Thr Ser Pro Asp Ser His Glu Pro Met Lys 
            100                 105                 110         


Lys Lys Lys Val Gly Arg Lys Pro Lys Thr Gln Gln Ser Pro Ile Ser 
        115                 120                 125             


Asn Gly Ser Pro Glu Leu Gly Ile Lys Lys Lys Pro Arg Glu Gly Lys 
    130                 135                 140                 


Gly Asn Thr Thr Tyr Leu Trp Glu Phe Leu Leu Asp Leu Leu Gln Asp 
145                 150                 155                 160 


Lys Asn Thr Cys Pro Arg Tyr Ile Lys Trp Thr Gln Arg Glu Lys Gly 
                165                 170                 175     


Ile Phe Lys Leu Val Asp Ser Lys Ala Val Ser Lys Leu Trp Gly Lys 
            180                 185                 190         


His Lys Asn Lys Pro Asp Met Asn Tyr Glu Thr Met Gly Arg Ala Leu 
        195                 200                 205             


Arg Tyr Tyr Tyr Gln Arg Gly Ile Leu Ala Lys Val Glu Gly Gln Arg 
    210                 215                 220                 


Leu Val Tyr Gln Phe Lys Asp Met Pro Lys Asn Ile Val Val Ile Asp 
225                 230                 235                 240 


Asp Asp Lys Ser Glu Thr Cys Asn Glu Asp Leu Ala Gly Thr Thr Asp 
                245                 250                 255     


Glu Lys Ser Leu Glu Arg Val Ser Leu Ser Ala Glu Ser Leu Leu Lys 
            260                 265                 270         


Ala Ala Ser Ser Val Arg Ser Gly Lys Asn Ser Ser Pro Ile Asn Cys 
        275                 280                 285             


Ser Arg Ala Glu Lys Gly Val Ala Arg Val Val Asn Ile Thr Ser Pro 
    290                 295                 300                 


Gly His Asp Ala Ser Ser Arg Ser Pro Thr Thr Thr Ala Ser Val Ser 
305                 310                 315                 320 


Ala Thr Ala Ala Pro Arg Thr Val Arg Val Ala Met Gln Val Pro Val 
                325                 330                 335     


Val Met Thr Ser Leu Gly Gln Lys Ile Ser Thr Val Ala Val Gln Ser 
            340                 345                 350         


Val Asn Ala Gly Ala Pro Leu Ile Thr Ser Thr Ser Pro Thr Thr Ala 
        355                 360                 365             


Thr Ser Pro Lys Val Val Ile Gln Thr Ile Pro Thr Val Met Pro Ala 
    370                 375                 380                 


Ser Thr Glu Asn Gly Asp Lys Ile Thr Met Gln Pro Ala Lys Ile Ile 
385                 390                 395                 400 


Thr Ile Pro Ala Thr Gln Leu Ala Gln Cys Gln Leu Gln Thr Lys Ser 
                405                 410                 415     


Asn Leu Thr Gly Ser Gly Ser Ile Asn Ile Val Gly Thr Pro Leu Ala 
            420                 425                 430         


Val Arg Ala Leu Thr Pro Val Ser Ile Ala His Gly Thr Pro Val Met 
        435                 440                 445             


Arg Leu Ser Met Pro Thr Gln Gln Ala Ser Gly Gln Thr Pro Pro Arg 
    450                 455                 460                 


Val Ile Ser Ala Val Ile Lys Gly Pro Glu Val Lys Ser Glu Ala Val 
465                 470                 475                 480 


Ala Lys Lys Gln Glu His Asp Val Lys Thr Leu Gln Leu Val Glu Glu 
                485                 490                 495     


Lys Pro Ala Asp Gly Asn Lys Thr Val Thr His Val Val Val Val Ser 
            500                 505                 510         


Ala Pro Ser Ala Ile Ala Leu Pro Val Thr Met Lys Thr Glu Gly Leu 
        515                 520                 525             


Val Thr Cys Glu Lys 
    530             


<210>  2855
<211>  356
<212>  PRT
<213>  homo sapiens

<400>  2855

Met Thr Lys Ser Tyr Ser Glu Ser Gly Leu Met Gly Glu Pro Gln Pro 
1               5                   10                  15      


Gln Gly Pro Pro Ser Trp Thr Asp Glu Cys Leu Ser Ser Gln Asp Glu 
            20                  25                  30          


Glu His Glu Ala Asp Lys Lys Glu Asp Asp Leu Glu Ala Met Asn Ala 
        35                  40                  45              


Glu Glu Asp Ser Leu Arg Asn Gly Gly Glu Glu Glu Asp Glu Asp Glu 
    50                  55                  60                  


Asp Leu Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp Asp Asp Gln Lys 
65                  70                  75                  80  


Pro Lys Arg Arg Gly Pro Lys Lys Lys Lys Met Thr Lys Ala Arg Leu 
                85                  90                  95      


Glu Arg Phe Lys Leu Arg Arg Met Lys Ala Asn Ala Arg Glu Arg Asn 
            100                 105                 110         


Arg Met His Gly Leu Asn Ala Ala Leu Asp Asn Leu Arg Lys Val Val 
        115                 120                 125             


Pro Cys Tyr Ser Lys Thr Gln Lys Leu Ser Lys Ile Glu Thr Leu Arg 
    130                 135                 140                 


Leu Ala Lys Asn Tyr Ile Trp Ala Leu Ser Glu Ile Leu Arg Ser Gly 
145                 150                 155                 160 


Lys Ser Pro Asp Leu Val Ser Phe Val Gln Thr Leu Cys Lys Gly Leu 
                165                 170                 175     


Ser Gln Pro Thr Thr Asn Leu Val Ala Gly Cys Leu Gln Leu Asn Pro 
            180                 185                 190         


Arg Thr Phe Leu Pro Glu Gln Asn Gln Asp Met Pro Pro His Leu Pro 
        195                 200                 205             


Thr Ala Ser Ala Ser Phe Pro Val His Pro Tyr Ser Tyr Gln Ser Pro 
    210                 215                 220                 


Gly Leu Pro Ser Pro Pro Tyr Gly Thr Met Asp Ser Ser His Val Phe 
225                 230                 235                 240 


His Val Lys Pro Pro Pro His Ala Tyr Ser Ala Ala Leu Glu Pro Phe 
                245                 250                 255     


Phe Glu Ser Pro Leu Thr Asp Cys Thr Ser Pro Ser Phe Asp Gly Pro 
            260                 265                 270         


Leu Ser Pro Pro Leu Ser Ile Asn Gly Asn Phe Ser Phe Lys His Glu 
        275                 280                 285             


Pro Ser Ala Glu Phe Glu Lys Asn Tyr Ala Phe Thr Met His Tyr Pro 
    290                 295                 300                 


Ala Ala Thr Leu Ala Gly Ala Gln Ser His Gly Ser Ile Phe Ser Gly 
305                 310                 315                 320 


Thr Ala Ala Pro Arg Cys Glu Ile Pro Ile Asp Asn Ile Met Ser Phe 
                325                 330                 335     


Asp Ser His Ser His His Glu Arg Val Met Ser Ala Gln Leu Asn Ala 
            340                 345                 350         


Ile Phe His Asp 
        355     


<210>  2856
<211>  499
<212>  PRT
<213>  homo sapiens

<400>  2856

Met Gly Arg Lys Lys Ile Gln Ile Thr Arg Ile Met Asp Glu Arg Asn 
1               5                   10                  15      


Arg Gln Val Thr Phe Thr Lys Arg Lys Phe Gly Leu Met Lys Lys Ala 
            20                  25                  30          


Tyr Glu Leu Ser Val Leu Cys Asp Cys Glu Ile Ala Leu Ile Ile Phe 
        35                  40                  45              


Asn Ser Ser Asn Lys Leu Phe Gln Tyr Ala Ser Thr Asp Met Asp Lys 
    50                  55                  60                  


Val Leu Leu Lys Tyr Thr Glu Tyr Asn Glu Pro His Glu Ser Arg Thr 
65                  70                  75                  80  


Asn Ser Asp Ile Val Glu Ala Leu Asn Lys Lys Glu His Arg Gly Cys 
                85                  90                  95      


Asp Ser Pro Asp Pro Asp Thr Ser Tyr Val Leu Thr Pro His Thr Glu 
            100                 105                 110         


Glu Lys Tyr Lys Lys Ile Asn Glu Glu Phe Asp Asn Met Met Arg Asn 
        115                 120                 125             


His Lys Ile Ala Pro Gly Leu Pro Pro Gln Asn Phe Ser Met Ser Val 
    130                 135                 140                 


Thr Val Pro Val Thr Ser Pro Asn Ala Leu Ser Tyr Thr Asn Pro Gly 
145                 150                 155                 160 


Ser Ser Leu Val Ser Pro Ser Leu Ala Ala Ser Ser Thr Leu Thr Asp 
                165                 170                 175     


Ser Ser Met Leu Ser Pro Pro Gln Thr Thr Leu His Arg Asn Val Ser 
            180                 185                 190         


Pro Gly Ala Pro Gln Arg Pro Pro Ser Thr Gly Asn Ala Gly Gly Met 
        195                 200                 205             


Leu Ser Thr Thr Asp Leu Thr Val Pro Asn Gly Ala Gly Ser Ser Pro 
    210                 215                 220                 


Val Gly Asn Gly Phe Val Asn Ser Arg Ala Ser Pro Asn Leu Ile Gly 
225                 230                 235                 240 


Ala Thr Gly Ala Asn Ser Leu Gly Lys Val Met Pro Thr Lys Ser Pro 
                245                 250                 255     


Pro Pro Pro Gly Gly Gly Asn Leu Gly Met Asn Ser Arg Lys Pro Asp 
            260                 265                 270         


Leu Arg Val Val Ile Pro Pro Ser Ser Lys Gly Met Met Pro Pro Leu 
        275                 280                 285             


Asn Thr Gln Arg Ile Ser Ser Ser Gln Ala Thr Gln Pro Leu Ala Thr 
    290                 295                 300                 


Pro Val Val Ser Val Thr Thr Pro Ser Leu Pro Pro Gln Gly Leu Val 
305                 310                 315                 320 


Tyr Ser Ala Met Pro Thr Ala Tyr Asn Thr Asp Tyr Ser Leu Thr Ser 
                325                 330                 335     


Ala Asp Leu Ser Ala Leu Gln Gly Phe Asn Ser Pro Gly Met Leu Ser 
            340                 345                 350         


Leu Gly Gln Val Ser Ala Trp Gln Gln His His Leu Gly Gln Ala Ala 
        355                 360                 365             


Leu Ser Ser Leu Val Ala Gly Gly Gln Leu Ser Gln Gly Ser Asn Leu 
    370                 375                 380                 


Ser Ile Asn Thr Asn Gln Asn Ile Ser Ile Lys Ser Glu Pro Ile Ser 
385                 390                 395                 400 


Pro Pro Arg Asp Arg Met Thr Pro Ser Gly Phe Gln Gln Gln Gln Gln 
                405                 410                 415     


Gln Gln Gln Gln Gln Gln Pro Pro Pro Pro Pro Gln Pro Gln Pro Gln 
            420                 425                 430         


Pro Pro Gln Pro Gln Pro Arg Gln Glu Met Gly Arg Ser Pro Val Asp 
        435                 440                 445             


Ser Leu Ser Ser Ser Ser Ser Ser Tyr Asp Gly Ser Asp Arg Glu Asp 
    450                 455                 460                 


Pro Arg Gly Asp Phe His Ser Pro Ile Val Leu Gly Arg Pro Pro Asn 
465                 470                 475                 480 


Thr Glu Asp Arg Glu Ser Pro Ser Val Lys Arg Met Arg Met Asp Ala 
                485                 490                 495     


Trp Val Thr 
            


<210>  2857
<211>  350
<212>  PRT
<213>  homo sapiens

<400>  2857

Met Gly Cys Phe Phe Ser Lys Arg Arg Lys Ala Asp Lys Glu Ser Arg 
1               5                   10                  15      


Pro Glu Asn Glu Glu Glu Arg Pro Lys Gln Tyr Ser Trp Asp Gln Arg 
            20                  25                  30          


Glu Lys Val Asp Pro Lys Asp Tyr Met Phe Ser Gly Leu Lys Asp Glu 
        35                  40                  45              


Thr Val Gly Arg Leu Pro Gly Thr Val Ala Gly Gln Gln Phe Leu Ile 
    50                  55                  60                  


Gln Asp Cys Glu Asn Cys Asn Ile Tyr Ile Phe Asp His Ser Ala Thr 
65                  70                  75                  80  


Val Thr Ile Asp Asp Cys Thr Asn Cys Ile Ile Phe Leu Gly Pro Val 
                85                  90                  95      


Lys Gly Ser Val Phe Phe Arg Asn Cys Arg Asp Cys Lys Cys Thr Leu 
            100                 105                 110         


Ala Cys Gln Gln Phe Arg Val Arg Asp Cys Arg Lys Leu Glu Val Phe 
        115                 120                 125             


Leu Cys Cys Ala Thr Gln Pro Ile Ile Glu Ser Ser Ser Asn Ile Lys 
    130                 135                 140                 


Phe Gly Cys Phe Gln Trp Tyr Tyr Pro Glu Leu Ala Phe Gln Phe Lys 
145                 150                 155                 160 


Asp Ala Gly Leu Ser Ile Phe Asn Asn Thr Trp Ser Asn Ile His Asp 
                165                 170                 175     


Phe Thr Pro Val Ser Gly Glu Leu Asn Trp Ser Leu Leu Pro Glu Asp 
            180                 185                 190         


Ala Val Val Gln Asp Tyr Val Pro Ile Pro Thr Thr Glu Glu Leu Lys 
        195                 200                 205             


Ala Val Arg Val Ser Thr Glu Ala Asn Arg Ser Ile Val Pro Ile Ser 
    210                 215                 220                 


Arg Gly Gln Arg Gln Lys Ser Ser Asp Glu Ser Cys Leu Val Val Leu 
225                 230                 235                 240 


Phe Ala Gly Asp Tyr Thr Ile Ala Asn Ala Arg Lys Leu Ile Asp Glu 
                245                 250                 255     


Met Val Gly Lys Gly Phe Phe Leu Val Gln Thr Lys Glu Val Ser Met 
            260                 265                 270         


Lys Ala Glu Asp Ala Gln Arg Val Phe Arg Glu Lys Ala Pro Asp Phe 
        275                 280                 285             


Leu Pro Leu Leu Asn Lys Gly Pro Val Ile Ala Leu Glu Phe Asn Gly 
    290                 295                 300                 


Asp Gly Ala Val Glu Val Cys Gln Leu Ile Val Asn Glu Ile Phe Asn 
305                 310                 315                 320 


Gly Thr Lys Met Phe Val Ser Glu Ser Lys Glu Thr Ala Ser Gly Asp 
                325                 330                 335     


Val Asp Ser Phe Tyr Asn Phe Ala Asp Ile Gln Met Gly Ile 
            340                 345                 350 


<210>  2858
<211>  2725
<212>  PRT
<213>  homo sapiens

<400>  2858

Met Met Asn Asn Ser Gly Tyr Ser Asp Ala Gly Leu Gly Leu Gly Asp 
1               5                   10                  15      


Glu Thr Asp Glu Met Pro Ser Thr Glu Lys Asp Leu Ala Glu Asp Ala 
            20                  25                  30          


Pro Trp Lys Lys Ile Gln Gln Asn Thr Phe Thr Arg Trp Cys Asn Glu 
        35                  40                  45              


His Leu Lys Cys Val Gly Lys Arg Leu Thr Asp Leu Gln Arg Asp Leu 
    50                  55                  60                  


Ser Asp Gly Leu Arg Leu Ile Ala Leu Leu Glu Val Leu Ser Gln Lys 
65                  70                  75                  80  


Arg Met Tyr Arg Lys Phe His Pro Arg Pro Asn Phe Arg Gln Met Lys 
                85                  90                  95      


Leu Glu Asn Val Ser Val Ala Leu Glu Phe Leu Glu Arg Glu His Ile 
            100                 105                 110         


Lys Leu Val Ser Ile Asp Ser Lys Ala Ile Val Asp Gly Asn Leu Lys 
        115                 120                 125             


Leu Ile Leu Gly Leu Ile Trp Thr Leu Ile Leu His Tyr Ser Ile Ser 
    130                 135                 140                 


Met Pro Met Trp Glu Asp Glu Asp Asp Glu Asp Ala Arg Lys Gln Thr 
145                 150                 155                 160 


Pro Lys Gln Arg Leu Leu Gly Trp Ile Gln Asn Lys Val Pro Gln Leu 
                165                 170                 175     


Pro Ile Thr Asn Phe Asn Arg Asp Trp Gln Asp Gly Lys Ala Leu Gly 
            180                 185                 190         


Ala Leu Val Asp Asn Cys Ala Pro Gly Leu Cys Pro Asp Trp Glu Ala 
        195                 200                 205             


Trp Asp Pro Asn Gln Pro Val Glu Asn Ala Arg Glu Ala Met Gln Gln 
    210                 215                 220                 


Ala Asp Asp Trp Leu Gly Val Pro Gln Val Ile Ala Pro Glu Glu Ile 
225                 230                 235                 240 


Val Asp Pro Asn Val Asp Glu His Ser Val Met Thr Tyr Leu Ser Gln 
                245                 250                 255     


Phe Pro Lys Ala Lys Leu Lys Pro Gly Ala Pro Val Arg Ser Lys Gln 
            260                 265                 270         


Leu Asn Pro Lys Lys Ala Ile Ala Tyr Gly Pro Gly Ile Glu Pro Gln 
        275                 280                 285             


Gly Asn Thr Val Leu Gln Pro Ala His Phe Thr Val Gln Thr Val Asp 
    290                 295                 300                 


Ala Gly Val Gly Glu Val Leu Val Tyr Ile Glu Asp Pro Glu Gly His 
305                 310                 315                 320 


Thr Glu Glu Ala Lys Val Val Pro Asn Asn Asp Lys Asp Arg Thr Tyr 
                325                 330                 335     


Ala Val Ser Tyr Val Pro Lys Val Ala Gly Leu His Lys Val Thr Val 
            340                 345                 350         


Leu Phe Ala Gly Gln Asn Ile Glu Arg Ser Pro Phe Glu Val Asn Val 
        355                 360                 365             


Gly Met Ala Leu Gly Asp Ala Asn Lys Val Ser Ala Arg Gly Pro Gly 
    370                 375                 380                 


Leu Glu Pro Val Gly Asn Val Ala Asn Lys Pro Thr Tyr Phe Asp Ile 
385                 390                 395                 400 


Tyr Thr Ala Gly Ala Gly Thr Gly Asp Val Ala Val Val Ile Val Asp 
                405                 410                 415     


Pro Gln Gly Arg Arg Asp Thr Val Glu Val Ala Leu Glu Asp Lys Gly 
            420                 425                 430         


Asp Ser Thr Phe Arg Cys Thr Tyr Arg Pro Ala Met Glu Gly Pro His 
        435                 440                 445             


Thr Val His Val Ala Phe Ala Gly Ala Pro Ile Thr Arg Ser Pro Phe 
    450                 455                 460                 


Pro Val His Val Ser Glu Ala Cys Asn Pro Asn Ala Cys Arg Ala Ser 
465                 470                 475                 480 


Gly Arg Gly Leu Gln Pro Lys Gly Val Arg Val Lys Glu Val Ala Asp 
                485                 490                 495     


Phe Lys Val Phe Thr Lys Gly Ala Gly Ser Gly Glu Leu Lys Val Thr 
            500                 505                 510         


Val Lys Gly Pro Lys Gly Thr Glu Glu Pro Val Lys Val Arg Glu Ala 
        515                 520                 525             


Gly Asp Gly Val Phe Glu Cys Glu Tyr Tyr Pro Val Val Pro Gly Lys 
    530                 535                 540                 


Tyr Val Val Thr Ile Thr Trp Gly Gly Tyr Ala Ile Pro Arg Ser Pro 
545                 550                 555                 560 


Phe Glu Val Gln Val Ser Pro Glu Ala Gly Val Gln Lys Val Arg Ala 
                565                 570                 575     


Trp Gly Pro Gly Leu Glu Thr Gly Gln Val Gly Lys Ser Ala Asp Phe 
            580                 585                 590         


Val Val Glu Ala Ile Gly Thr Glu Val Gly Thr Leu Gly Phe Ser Ile 
        595                 600                 605             


Glu Gly Pro Ser Gln Ala Lys Ile Glu Cys Asp Asp Lys Gly Asp Gly 
    610                 615                 620                 


Ser Cys Asp Val Arg Tyr Trp Pro Thr Glu Pro Gly Glu Tyr Ala Val 
625                 630                 635                 640 


His Val Ile Cys Asp Asp Glu Asp Ile Arg Asp Ser Pro Phe Ile Ala 
                645                 650                 655     


His Ile Leu Pro Ala Pro Pro Asp Cys Phe Pro Asp Lys Val Lys Ala 
            660                 665                 670         


Phe Gly Pro Gly Leu Glu Pro Thr Gly Cys Ile Val Asp Lys Pro Ala 
        675                 680                 685             


Glu Phe Thr Ile Asp Ala Arg Ala Ala Gly Lys Gly Asp Leu Lys Leu 
    690                 695                 700                 


Tyr Ala Gln Asp Ala Asp Gly Cys Pro Ile Asp Ile Lys Val Ile Pro 
705                 710                 715                 720 


Asn Gly Asp Gly Thr Phe Arg Cys Ser Tyr Val Pro Thr Lys Pro Ile 
                725                 730                 735     


Lys His Thr Ile Ile Ile Ser Trp Gly Gly Val Asn Val Pro Lys Ser 
            740                 745                 750         


Pro Phe Arg Val Asn Val Gly Glu Gly Ser His Pro Glu Arg Val Lys 
        755                 760                 765             


Val Tyr Gly Pro Gly Val Glu Lys Thr Gly Leu Lys Ala Asn Glu Pro 
    770                 775                 780                 


Thr Tyr Phe Thr Val Asp Cys Ser Glu Ala Gly Gln Gly Asp Val Ser 
785                 790                 795                 800 


Ile Gly Ile Lys Cys Ala Pro Gly Val Val Gly Pro Ala Glu Ala Asp 
                805                 810                 815     


Ile Asp Phe Asp Ile Ile Lys Asn Asp Asn Asp Thr Phe Thr Val Lys 
            820                 825                 830         


Tyr Thr Pro Pro Gly Ala Gly Arg Tyr Thr Ile Met Val Leu Phe Ala 
        835                 840                 845             


Asn Gln Glu Ile Pro Ala Ser Pro Phe His Ile Lys Val Asp Pro Ser 
    850                 855                 860                 


His Asp Ala Ser Lys Val Lys Ala Glu Gly Pro Gly Leu Asn Arg Thr 
865                 870                 875                 880 


Gly Val Glu Val Gly Lys Pro Thr His Phe Thr Val Leu Thr Lys Gly 
                885                 890                 895     


Ala Gly Lys Ala Lys Leu Asp Val Gln Phe Ala Gly Thr Ala Lys Gly 
            900                 905                 910         


Glu Val Val Arg Asp Phe Glu Ile Ile Asp Asn His Asp Tyr Ser Tyr 
        915                 920                 925             


Thr Val Lys Tyr Thr Ala Val Gln Gln Gly Asn Met Ala Val Thr Val 
    930                 935                 940                 


Thr Tyr Gly Gly Asp Pro Val Pro Lys Ser Pro Phe Val Val Asn Val 
945                 950                 955                 960 


Ala Pro Pro Leu Asp Leu Ser Lys Ile Lys Val Gln Gly Leu Asn Ser 
                965                 970                 975     


Lys Val Ala Val Gly Gln Glu Gln Ala Phe Ser Val Asn Thr Arg Gly 
            980                 985                 990         


Ala Gly Gly Gln Gly Gln Leu Asp  Val Arg Met Thr Ser  Pro Ser Arg 
        995                 1000                 1005             


Arg Pro  Ile Pro Cys Lys Leu  Glu Pro Gly Gly Gly  Ala Glu Ala 
    1010                 1015                 1020             


Gln Ala  Val Arg Tyr Met Pro  Pro Glu Glu Gly Pro  Tyr Lys Val 
    1025                 1030                 1035             


Asp Ile  Thr Tyr Asp Gly His  Pro Val Pro Gly Ser  Pro Phe Ala 
    1040                 1045                 1050             


Val Glu  Gly Val Leu Pro Pro  Asp Pro Ser Lys Val  Cys Ala Tyr 
    1055                 1060                 1065             


Gly Pro  Gly Leu Lys Gly Gly  Leu Val Gly Thr Pro  Ala Pro Phe 
    1070                 1075                 1080             


Ser Ile  Asp Thr Lys Gly Ala  Gly Thr Gly Gly Leu  Gly Leu Thr 
    1085                 1090                 1095             


Val Glu  Gly Pro Cys Glu Ala  Lys Ile Glu Cys Gln  Asp Asn Gly 
    1100                 1105                 1110             


Asp Gly  Ser Cys Ala Val Ser  Tyr Leu Pro Thr Glu  Pro Gly Glu 
    1115                 1120                 1125             


Tyr Thr  Ile Asn Ile Leu Phe  Ala Glu Ala His Ile  Pro Gly Ser 
    1130                 1135                 1140             


Pro Phe  Lys Ala Thr Ile Arg  Pro Val Phe Asp Pro  Ser Lys Val 
    1145                 1150                 1155             


Arg Ala  Ser Gly Pro Gly Leu  Glu Arg Gly Lys Val  Gly Glu Ala 
    1160                 1165                 1170             


Ala Thr  Phe Thr Val Asp Cys  Ser Glu Ala Gly Glu  Ala Glu Leu 
    1175                 1180                 1185             


Thr Ile  Glu Ile Leu Ser Asp  Ala Gly Val Lys Ala  Glu Val Leu 
    1190                 1195                 1200             


Ile His  Asn Asn Ala Asp Gly  Thr Tyr His Ile Thr  Tyr Ser Pro 
    1205                 1210                 1215             


Ala Phe  Pro Gly Thr Tyr Thr  Ile Thr Ile Lys Tyr  Gly Gly His 
    1220                 1225                 1230             


Pro Val  Pro Lys Phe Pro Thr  Arg Val His Val Gln  Pro Ala Val 
    1235                 1240                 1245             


Asp Thr  Ser Gly Val Lys Val  Ser Gly Pro Gly Val  Glu Pro His 
    1250                 1255                 1260             


Gly Val  Leu Arg Glu Val Thr  Thr Glu Phe Thr Val  Asp Ala Arg 
    1265                 1270                 1275             


Ser Leu  Thr Ala Thr Gly Gly  Asn His Val Thr Ala  Arg Val Leu 
    1280                 1285                 1290             


Asn Pro  Ser Gly Ala Lys Thr  Asp Thr Tyr Val Thr  Asp Asn Gly 
    1295                 1300                 1305             


Asp Gly  Thr Tyr Arg Val Gln  Tyr Thr Ala Tyr Glu  Glu Gly Val 
    1310                 1315                 1320             


His Leu  Val Glu Val Leu Tyr  Asp Glu Val Ala Val  Pro Lys Ser 
    1325                 1330                 1335             


Pro Phe  Arg Val Gly Val Thr  Glu Gly Cys Asp Pro  Thr Arg Val 
    1340                 1345                 1350             


Arg Ala  Phe Gly Pro Gly Leu  Glu Gly Gly Leu Val  Asn Lys Ala 
    1355                 1360                 1365             


Asn Arg  Phe Thr Val Glu Thr  Arg Gly Ala Gly Thr  Gly Gly Leu 
    1370                 1375                 1380             


Gly Leu  Ala Ile Glu Gly Pro  Ser Glu Ala Lys Met  Ser Cys Lys 
    1385                 1390                 1395             


Asp Asn  Lys Asp Gly Ser Cys  Thr Val Glu Tyr Ile  Pro Phe Thr 
    1400                 1405                 1410             


Pro Gly  Asp Tyr Asp Val Asn  Ile Thr Phe Gly Gly  Arg Pro Ile 
    1415                 1420                 1425             


Pro Gly  Ser Pro Phe Arg Val  Pro Val Lys Asp Val  Val Asp Pro 
    1430                 1435                 1440             


Gly Lys  Val Lys Cys Ser Gly  Pro Gly Leu Gly Ala  Gly Val Arg 
    1445                 1450                 1455             


Ala Arg  Val Pro Gln Thr Phe  Thr Val Asp Cys Ser  Gln Ala Gly 
    1460                 1465                 1470             


Arg Ala  Pro Leu Gln Val Ala  Val Leu Gly Pro Thr  Gly Val Ala 
    1475                 1480                 1485             


Glu Pro  Val Glu Val Arg Asp  Asn Gly Asp Gly Thr  His Thr Val 
    1490                 1495                 1500             


His Tyr  Thr Pro Ala Thr Asp  Gly Pro Tyr Thr Val  Ala Val Lys 
    1505                 1510                 1515             


Tyr Ala  Asp Gln Glu Val Pro  Arg Ser Pro Phe Lys  Ile Lys Val 
    1520                 1525                 1530             


Leu Pro  Ala His Asp Ala Ser  Lys Val Arg Ala Ser  Gly Pro Gly 
    1535                 1540                 1545             


Leu Asn  Ala Ser Gly Ile Pro  Ala Ser Leu Pro Val  Glu Phe Thr 
    1550                 1555                 1560             


Ile Asp  Ala Arg Asp Ala Gly  Glu Gly Leu Leu Thr  Val Gln Ile 
    1565                 1570                 1575             


Leu Asp  Pro Glu Gly Lys Pro  Lys Lys Ala Asn Ile  Arg Asp Asn 
    1580                 1585                 1590             


Gly Asp  Gly Thr Tyr Thr Val  Ser Tyr Leu Pro Asp  Met Ser Gly 
    1595                 1600                 1605             


Arg Tyr  Thr Ile Thr Ile Lys  Tyr Gly Gly Asp Glu  Ile Pro Tyr 
    1610                 1615                 1620             


Ser Pro  Phe Arg Ile His Ala  Leu Pro Thr Gly Asp  Ala Ser Lys 
    1625                 1630                 1635             


Cys Leu  Val Thr Val Ser Ile  Gly Gly His Gly Leu  Gly Ala Cys 
    1640                 1645                 1650             


Leu Gly  Pro Arg Ile Gln Ile  Gly Gln Glu Thr Val  Ile Thr Val 
    1655                 1660                 1665             


Asp Ala  Lys Ala Ala Gly Glu  Gly Lys Val Thr Cys  Thr Val Ser 
    1670                 1675                 1680             


Thr Pro  Asp Gly Ala Glu Leu  Asp Val Asp Val Val  Glu Asn His 
    1685                 1690                 1695             


Asp Gly  Thr Phe Asp Ile Tyr  Tyr Thr Ala Pro Glu  Pro Gly Lys 
    1700                 1705                 1710             


Tyr Val  Ile Thr Ile Arg Phe  Gly Gly Glu His Ile  Pro Asn Ser 
    1715                 1720                 1725             


Pro Phe  His Val Leu Ala Cys  Asp Pro Leu Pro His  Glu Glu Glu 
    1730                 1735                 1740             


Pro Ser  Glu Val Pro Gln Leu  Arg Gln Pro Tyr Ala  Pro Pro Arg 
    1745                 1750                 1755             


Pro Gly  Ala Arg Pro Thr His  Trp Ala Thr Glu Glu  Pro Val Val 
    1760                 1765                 1770             


Pro Val  Glu Pro Met Glu Ser  Met Leu Arg Pro Phe  Asn Leu Val 
    1775                 1780                 1785             


Ile Pro  Phe Ala Val Gln Lys  Gly Glu Leu Thr Gly  Glu Val Arg 
    1790                 1795                 1800             


Met Pro  Ser Gly Lys Thr Ala  Arg Pro Asn Ile Thr  Asp Asn Lys 
    1805                 1810                 1815             


Asp Gly  Thr Ile Thr Val Arg  Tyr Ala Pro Thr Glu  Lys Gly Leu 
    1820                 1825                 1830             


His Gln  Met Gly Ile Lys Tyr  Asp Gly Asn His Ile  Pro Gly Ser 
    1835                 1840                 1845             


Pro Leu  Gln Phe Tyr Val Asp  Ala Ile Asn Ser Arg  His Val Ser 
    1850                 1855                 1860             


Ala Tyr  Gly Pro Gly Leu Ser  His Gly Met Val Asn  Lys Pro Ala 
    1865                 1870                 1875             


Thr Phe  Thr Ile Val Thr Lys  Asp Ala Gly Glu Gly  Gly Leu Ser 
    1880                 1885                 1890             


Leu Ala  Val Glu Gly Pro Ser  Lys Ala Glu Ile Thr  Cys Lys Asp 
    1895                 1900                 1905             


Asn Lys  Asp Gly Thr Cys Thr  Val Ser Tyr Leu Pro  Thr Ala Pro 
    1910                 1915                 1920             


Gly Asp  Tyr Ser Ile Ile Val  Arg Phe Asp Asp Lys  His Ile Pro 
    1925                 1930                 1935             


Gly Ser  Pro Phe Thr Ala Lys  Ile Thr Gly Asp Asp  Ser Met Arg 
    1940                 1945                 1950             


Thr Ser  Gln Leu Asn Val Gly  Thr Ser Thr Asp Val  Ser Leu Lys 
    1955                 1960                 1965             


Ile Thr  Glu Ser Asp Leu Ser  Gln Leu Thr Ala Ser  Ile Arg Ala 
    1970                 1975                 1980             


Pro Ser  Gly Asn Glu Glu Pro  Cys Leu Leu Lys Arg  Leu Pro Asn 
    1985                 1990                 1995             


Arg His  Ile Gly Ile Ser Phe  Thr Pro Lys Glu Val  Gly Glu His 
    2000                 2005                 2010             


Val Val  Ser Val Arg Lys Ser  Gly Lys His Val Thr  Asn Ser Pro 
    2015                 2020                 2025             


Phe Lys  Ile Leu Val Gly Pro  Ser Glu Ile Gly Asp  Ala Ser Lys 
    2030                 2035                 2040             


Val Arg  Val Trp Gly Lys Gly  Leu Ser Glu Gly His  Thr Phe Gln 
    2045                 2050                 2055             


Val Ala  Glu Phe Ile Val Asp  Thr Arg Asn Ala Gly  Tyr Gly Gly 
    2060                 2065                 2070             


Leu Gly  Leu Ser Ile Glu Gly  Pro Ser Lys Val Asp  Ile Asn Cys 
    2075                 2080                 2085             


Glu Asp  Met Glu Asp Gly Thr  Cys Lys Val Thr Tyr  Cys Pro Thr 
    2090                 2095                 2100             


Glu Pro  Gly Thr Tyr Ile Ile  Asn Ile Lys Phe Ala  Asp Lys His 
    2105                 2110                 2115             


Val Pro  Gly Ser Pro Phe Thr  Val Lys Val Thr Gly  Glu Gly Arg 
    2120                 2125                 2130             


Met Lys  Glu Ser Ile Thr Arg  Arg Arg Gln Ala Pro  Ser Ile Ala 
    2135                 2140                 2145             


Thr Ile  Gly Ser Thr Cys Asp  Leu Asn Leu Lys Ile  Pro Gly Asn 
    2150                 2155                 2160             


Trp Phe  Gln Met Val Ser Ala  Gln Glu Arg Leu Thr  Arg Thr Phe 
    2165                 2170                 2175             


Thr Arg  Ser Ser His Thr Tyr  Thr Arg Thr Glu Arg  Thr Glu Ile 
    2180                 2185                 2190             


Ser Lys  Thr Arg Gly Gly Glu  Thr Lys Arg Glu Val  Arg Val Glu 
    2195                 2200                 2205             


Glu Ser  Thr Gln Val Gly Gly  Asp Pro Phe Pro Ala  Val Phe Gly 
    2210                 2215                 2220             


Asp Phe  Leu Gly Arg Glu Arg  Leu Gly Ser Phe Gly  Ser Ile Thr 
    2225                 2230                 2235             


Arg Gln  Gln Glu Gly Glu Ala  Ser Ser Gln Asp Met  Thr Ala Gln 
    2240                 2245                 2250             


Val Thr  Ser Pro Ser Gly Lys  Val Glu Ala Ala Glu  Ile Val Glu 
    2255                 2260                 2265             


Gly Glu  Asp Ser Ala Tyr Ser  Val Arg Phe Val Pro  Gln Glu Met 
    2270                 2275                 2280             


Gly Pro  His Thr Val Ala Val  Lys Tyr Arg Gly Gln  His Val Pro 
    2285                 2290                 2295             


Gly Ser  Pro Phe Gln Phe Thr  Val Gly Pro Leu Gly  Glu Gly Gly 
    2300                 2305                 2310             


Ala His  Lys Val Arg Ala Gly  Gly Thr Gly Leu Glu  Arg Gly Val 
    2315                 2320                 2325             


Ala Gly  Val Pro Ala Glu Phe  Ser Ile Trp Thr Arg  Glu Ala Gly 
    2330                 2335                 2340             


Ala Gly  Gly Leu Ser Ile Ala  Val Glu Gly Pro Ser  Lys Ala Glu 
    2345                 2350                 2355             


Ile Ala  Phe Glu Asp Arg Lys  Asp Gly Ser Cys Gly  Val Ser Tyr 
    2360                 2365                 2370             


Val Val  Gln Glu Pro Gly Asp  Tyr Glu Val Ser Ile  Lys Phe Asn 
    2375                 2380                 2385             


Asp Glu  His Ile Pro Asp Ser  Pro Phe Val Val Pro  Val Ala Ser 
    2390                 2395                 2400             


Leu Ser  Asp Asp Ala Arg Arg  Leu Thr Val Thr Ser  Leu Gln Glu 
    2405                 2410                 2415             


Thr Gly  Leu Lys Val Asn Gln  Pro Ala Ser Phe Ala  Val Gln Leu 
    2420                 2425                 2430             


Asn Gly  Ala Arg Gly Val Ile  Asp Ala Arg Val His  Thr Pro Ser 
    2435                 2440                 2445             


Gly Ala  Val Glu Glu Cys Tyr  Val Ser Glu Leu Asp  Ser Asp Lys 
    2450                 2455                 2460             


His Thr  Ile Arg Phe Ile Pro  His Glu Asn Gly Val  His Ser Ile 
    2465                 2470                 2475             


Asp Val  Lys Phe Asn Gly Ala  His Ile Pro Gly Ser  Pro Phe Lys 
    2480                 2485                 2490             


Ile Arg  Val Gly Glu Gln Ser  Gln Ala Gly Asp Pro  Gly Leu Val 
    2495                 2500                 2505             


Ser Ala  Tyr Gly Pro Gly Leu  Glu Gly Gly Thr Thr  Gly Val Ser 
    2510                 2515                 2520             


Ser Glu  Phe Ile Val Asn Thr  Leu Asn Ala Gly Ser  Gly Ala Leu 
    2525                 2530                 2535             


Ser Val  Thr Ile Asp Gly Pro  Ser Lys Val Gln Leu  Asp Cys Arg 
    2540                 2545                 2550             


Glu Cys  Pro Glu Gly His Val  Val Thr Tyr Thr Pro  Met Ala Pro 
    2555                 2560                 2565             


Gly Asn  Tyr Leu Ile Ala Ile  Lys Tyr Gly Gly Pro  Gln His Ile 
    2570                 2575                 2580             


Val Gly  Ser Pro Phe Lys Ala  Lys Val Thr Gly Pro  Arg Leu Ser 
    2585                 2590                 2595             


Gly Gly  His Ser Leu His Glu  Thr Ser Thr Val Leu  Val Glu Thr 
    2600                 2605                 2610             


Val Thr  Lys Ser Ser Ser Ser  Arg Gly Ser Ser Tyr  Ser Ser Ile 
    2615                 2620                 2625             


Pro Lys  Phe Ser Ser Asp Ala  Ser Lys Val Val Thr  Arg Gly Pro 
    2630                 2635                 2640             


Gly Leu  Ser Gln Ala Phe Val  Gly Gln Lys Asn Ser  Phe Thr Val 
    2645                 2650                 2655             


Asp Cys  Ser Lys Ala Gly Thr  Asn Met Met Met Val  Gly Val His 
    2660                 2665                 2670             


Gly Pro  Lys Thr Pro Cys Glu  Glu Val Tyr Val Lys  His Met Gly 
    2675                 2680                 2685             


Asn Arg  Val Tyr Asn Val Thr  Tyr Thr Val Lys Glu  Lys Gly Asp 
    2690                 2695                 2700             


Tyr Ile  Leu Ile Val Lys Trp  Gly Asp Glu Ser Val  Pro Gly Ser 
    2705                 2710                 2715             


Pro Phe  Lys Val Lys Val Pro  
    2720                 2725 


<210>  2859
<211>  599
<212>  PRT
<213>  homo sapiens

<400>  2859

Met Ala Asp Lys Leu Thr Arg Ile Ala Ile Val Asn His Asp Lys Cys 
1               5                   10                  15      


Lys Pro Lys Lys Cys Arg Gln Glu Cys Lys Lys Ser Cys Pro Val Val 
            20                  25                  30          


Arg Met Gly Lys Leu Cys Ile Glu Val Thr Pro Gln Ser Lys Ile Ala 
        35                  40                  45              


Trp Ile Ser Glu Thr Leu Cys Ile Gly Cys Gly Ile Cys Ile Lys Lys 
    50                  55                  60                  


Cys Pro Phe Gly Ala Leu Ser Ile Val Asn Leu Pro Ser Asn Leu Glu 
65                  70                  75                  80  


Lys Glu Thr Thr His Arg Tyr Cys Ala Asn Ala Phe Lys Leu His Arg 
                85                  90                  95      


Leu Pro Ile Pro Arg Pro Gly Glu Val Leu Gly Leu Val Gly Thr Asn 
            100                 105                 110         


Gly Ile Gly Lys Ser Thr Ala Leu Lys Ile Leu Ala Gly Lys Gln Lys 
        115                 120                 125             


Pro Asn Leu Gly Lys Tyr Asp Asp Pro Pro Asp Trp Gln Glu Ile Leu 
    130                 135                 140                 


Thr Tyr Phe Arg Gly Ser Glu Leu Gln Asn Tyr Phe Thr Lys Ile Leu 
145                 150                 155                 160 


Glu Asp Asp Leu Lys Ala Ile Ile Lys Pro Gln Tyr Val Asp Gln Ile 
                165                 170                 175     


Pro Lys Ala Ala Lys Gly Thr Val Gly Ser Ile Leu Asp Arg Lys Asp 
            180                 185                 190         


Glu Thr Lys Thr Gln Ala Ile Val Cys Gln Gln Leu Asp Leu Thr His 
        195                 200                 205             


Leu Lys Glu Arg Asn Val Glu Asp Leu Ser Gly Gly Glu Leu Gln Arg 
    210                 215                 220                 


Phe Ala Cys Ala Val Val Cys Ile Gln Lys Ala Asp Ile Phe Met Phe 
225                 230                 235                 240 


Asp Glu Pro Ser Ser Tyr Leu Asp Val Lys Gln Arg Leu Lys Ala Ala 
                245                 250                 255     


Ile Thr Ile Arg Ser Leu Ile Asn Pro Asp Arg Tyr Ile Ile Val Val 
            260                 265                 270         


Glu His Asp Leu Ser Val Leu Asp Tyr Leu Ser Asp Phe Ile Cys Cys 
        275                 280                 285             


Leu Tyr Gly Val Pro Ser Ala Tyr Gly Val Val Thr Met Pro Phe Ser 
    290                 295                 300                 


Val Arg Glu Gly Ile Asn Ile Phe Leu Asp Gly Tyr Val Pro Thr Glu 
305                 310                 315                 320 


Asn Leu Arg Phe Arg Asp Ala Ser Leu Val Phe Lys Val Ala Glu Thr 
                325                 330                 335     


Ala Asn Glu Glu Glu Val Lys Lys Met Cys Met Tyr Lys Tyr Pro Gly 
            340                 345                 350         


Met Lys Lys Lys Met Gly Glu Phe Glu Leu Ala Ile Val Ala Gly Glu 
        355                 360                 365             


Phe Thr Asp Ser Glu Ile Met Val Met Leu Gly Glu Asn Gly Thr Gly 
    370                 375                 380                 


Lys Thr Thr Phe Ile Arg Met Leu Ala Gly Arg Leu Lys Pro Asp Glu 
385                 390                 395                 400 


Gly Gly Glu Val Pro Val Leu Asn Val Ser Tyr Lys Pro Gln Lys Ile 
                405                 410                 415     


Ser Pro Lys Ser Thr Gly Ser Val Arg Gln Leu Leu His Glu Lys Ile 
            420                 425                 430         


Arg Asp Ala Tyr Thr His Pro Gln Phe Val Thr Asp Val Met Lys Pro 
        435                 440                 445             


Leu Gln Ile Glu Asn Ile Ile Asp Gln Glu Val Gln Thr Leu Ser Gly 
    450                 455                 460                 


Gly Glu Leu Gln Arg Val Ala Leu Ala Leu Cys Leu Gly Lys Pro Ala 
465                 470                 475                 480 


Asp Val Tyr Leu Ile Asp Glu Pro Ser Ala Tyr Leu Asp Ser Glu Gln 
                485                 490                 495     


Arg Leu Met Ala Ala Arg Val Val Lys Arg Phe Ile Leu His Ala Lys 
            500                 505                 510         


Lys Thr Ala Phe Val Val Glu His Asp Phe Ile Met Ala Thr Tyr Leu 
        515                 520                 525             


Ala Asp Arg Val Ile Val Phe Asp Gly Val Pro Ser Lys Asn Thr Val 
    530                 535                 540                 


Ala Asn Ser Pro Gln Thr Leu Leu Ala Gly Met Asn Lys Phe Leu Ser 
545                 550                 555                 560 


Gln Leu Glu Ile Thr Phe Arg Arg Asp Pro Asn Asn Tyr Arg Pro Arg 
                565                 570                 575     


Ile Asn Lys Leu Asn Ser Ile Lys Asp Val Glu Gln Lys Lys Ser Gly 
            580                 585                 590         


Asn Tyr Phe Phe Leu Asp Asp 
        595                 


<210>  2860
<211>  428
<212>  PRT
<213>  homo sapiens

<400>  2860

Met Asp Pro Ser Val Thr Leu Trp Gln Phe Leu Leu Gln Leu Leu Arg 
1               5                   10                  15      


Glu Gln Gly Asn Gly His Ile Ile Ser Trp Thr Ser Arg Asp Gly Gly 
            20                  25                  30          


Glu Phe Lys Leu Val Asp Ala Glu Glu Val Ala Arg Leu Trp Gly Leu 
        35                  40                  45              


Arg Lys Asn Lys Thr Asn Met Asn Tyr Asp Lys Leu Ser Arg Ala Leu 
    50                  55                  60                  


Arg Tyr Tyr Tyr Asp Lys Asn Ile Ile Arg Lys Val Ser Gly Gln Lys 
65                  70                  75                  80  


Phe Val Tyr Lys Phe Val Ser Tyr Pro Glu Val Ala Gly Cys Ser Thr 
                85                  90                  95      


Glu Asp Cys Pro Pro Gln Pro Glu Val Ser Val Thr Ser Thr Met Pro 
            100                 105                 110         


Asn Val Ala Pro Ala Ala Ile His Ala Ala Pro Gly Asp Thr Val Ser 
        115                 120                 125             


Gly Lys Pro Gly Thr Pro Lys Gly Ala Gly Met Ala Gly Pro Gly Gly 
    130                 135                 140                 


Leu Ala Arg Ser Ser Arg Asn Glu Tyr Met Arg Ser Gly Leu Tyr Ser 
145                 150                 155                 160 


Thr Phe Thr Ile Gln Ser Leu Gln Pro Gln Pro Pro Pro His Pro Arg 
                165                 170                 175     


Pro Ala Val Val Leu Pro Ser Ala Ala Pro Ala Gly Ala Ala Ala Pro 
            180                 185                 190         


Pro Ser Gly Ser Arg Ser Thr Ser Pro Ser Pro Leu Glu Ala Cys Leu 
        195                 200                 205             


Glu Ala Glu Glu Ala Gly Leu Pro Leu Gln Val Ile Leu Thr Pro Pro 
    210                 215                 220                 


Glu Ala Pro Asn Leu Lys Ser Glu Glu Leu Asn Val Glu Pro Gly Leu 
225                 230                 235                 240 


Gly Arg Ala Leu Pro Pro Glu Val Lys Val Glu Gly Pro Lys Glu Glu 
                245                 250                 255     


Leu Glu Val Ala Gly Glu Arg Gly Phe Val Pro Glu Thr Thr Lys Ala 
            260                 265                 270         


Glu Pro Glu Val Pro Pro Gln Glu Gly Val Pro Ala Arg Leu Pro Ala 
        275                 280                 285             


Val Val Met Asp Thr Ala Gly Gln Ala Gly Gly His Ala Ala Ser Ser 
    290                 295                 300                 


Pro Glu Ile Ser Gln Pro Gln Lys Gly Arg Lys Pro Arg Asp Leu Glu 
305                 310                 315                 320 


Leu Pro Leu Ser Pro Ser Leu Leu Gly Gly Pro Gly Pro Glu Arg Thr 
                325                 330                 335     


Pro Gly Ser Gly Ser Gly Ser Gly Leu Gln Ala Pro Gly Pro Ala Leu 
            340                 345                 350         


Thr Pro Ser Leu Leu Pro Thr His Thr Leu Thr Pro Val Leu Leu Thr 
        355                 360                 365             


Pro Ser Ser Leu Pro Pro Ser Ile His Phe Trp Ser Thr Leu Ser Pro 
    370                 375                 380                 


Ile Ala Pro Arg Ser Pro Ala Lys Leu Ser Phe Gln Phe Pro Ser Ser 
385                 390                 395                 400 


Gly Ser Ala Gln Val His Ile Pro Ser Ile Ser Val Asp Gly Leu Ser 
                405                 410                 415     


Thr Pro Val Val Leu Ser Pro Gly Pro Gln Lys Pro 
            420                 425             


<210>  2861
<211>  816
<212>  PRT
<213>  homo sapiens

<400>  2861

Met Glu Ser Arg Val Leu Leu Arg Thr Phe Cys Leu Ile Phe Gly Leu 
1               5                   10                  15      


Gly Ala Val Trp Gly Leu Gly Val Asp Pro Ser Leu Gln Ile Asp Val 
            20                  25                  30          


Leu Thr Glu Leu Glu Leu Gly Glu Ser Thr Thr Gly Val Arg Gln Val 
        35                  40                  45              


Pro Gly Leu His Asn Gly Thr Lys Ala Phe Leu Phe Gln Asp Thr Pro 
    50                  55                  60                  


Arg Ser Ile Lys Ala Ser Thr Ala Thr Ala Glu Gln Phe Phe Gln Lys 
65                  70                  75                  80  


Leu Arg Asn Lys His Glu Phe Thr Ile Leu Val Thr Leu Lys Gln Thr 
                85                  90                  95      


His Leu Asn Ser Gly Val Ile Leu Ser Ile His His Leu Asp His Arg 
            100                 105                 110         


Tyr Leu Glu Leu Glu Ser Ser Gly His Arg Asn Glu Val Arg Leu His 
        115                 120                 125             


Tyr Arg Ser Gly Ser His Arg Pro His Thr Glu Val Phe Pro Tyr Ile 
    130                 135                 140                 


Leu Ala Asp Asp Lys Trp His Lys Leu Ser Leu Ala Ile Ser Ala Ser 
145                 150                 155                 160 


His Leu Ile Leu His Ile Asp Cys Asn Lys Ile Tyr Glu Arg Val Val 
                165                 170                 175     


Glu Lys Pro Ser Thr Asp Leu Pro Leu Gly Thr Thr Phe Trp Leu Gly 
            180                 185                 190         


Gln Arg Asn Asn Ala His Gly Tyr Phe Lys Gly Ile Met Gln Asp Val 
        195                 200                 205             


Gln Leu Leu Val Met Pro Gln Gly Phe Ile Ala Gln Cys Pro Asp Leu 
    210                 215                 220                 


Asn Arg Thr Cys Pro Thr Cys Asn Asp Phe His Gly Leu Val Gln Lys 
225                 230                 235                 240 


Ile Met Glu Leu Gln Asp Ile Leu Ala Lys Thr Ser Ala Lys Leu Ser 
                245                 250                 255     


Arg Ala Glu Gln Arg Met Asn Arg Leu Asp Gln Cys Tyr Cys Glu Arg 
            260                 265                 270         


Thr Cys Thr Met Lys Gly Thr Thr Tyr Arg Glu Phe Glu Ser Trp Ile 
        275                 280                 285             


Asp Gly Cys Lys Asn Cys Thr Cys Leu Asn Gly Thr Ile Gln Cys Glu 
    290                 295                 300                 


Thr Leu Ile Cys Pro Asn Pro Asp Cys Pro Leu Lys Ser Ala Leu Ala 
305                 310                 315                 320 


Tyr Val Asp Gly Lys Cys Cys Lys Glu Cys Lys Ser Ile Cys Gln Phe 
                325                 330                 335     


Gln Gly Arg Thr Tyr Phe Glu Gly Glu Arg Asn Thr Val Tyr Ser Ser 
            340                 345                 350         


Ser Gly Val Cys Val Leu Tyr Glu Cys Lys Asp Gln Thr Met Lys Leu 
        355                 360                 365             


Val Glu Ser Ser Gly Cys Pro Ala Leu Asp Cys Pro Glu Ser His Gln 
    370                 375                 380                 


Ile Thr Leu Ser His Ser Cys Cys Lys Val Cys Lys Gly Tyr Asp Phe 
385                 390                 395                 400 


Cys Ser Glu Arg His Asn Cys Met Glu Asn Ser Ile Cys Arg Asn Leu 
                405                 410                 415     


Asn Asp Arg Ala Val Cys Ser Cys Arg Asp Gly Phe Arg Ala Leu Arg 
            420                 425                 430         


Glu Asp Asn Ala Tyr Cys Glu Asp Ile Asp Glu Cys Ala Glu Gly Arg 
        435                 440                 445             


His Tyr Cys Arg Glu Asn Thr Met Cys Val Asn Thr Pro Gly Ser Phe 
    450                 455                 460                 


Met Cys Ile Cys Lys Thr Gly Tyr Ile Arg Ile Asp Asp Tyr Ser Cys 
465                 470                 475                 480 


Thr Glu His Asp Glu Cys Ile Thr Asn Gln His Asn Cys Asp Glu Asn 
                485                 490                 495     


Ala Leu Cys Phe Asn Thr Val Gly Gly His Asn Cys Val Cys Lys Pro 
            500                 505                 510         


Gly Tyr Thr Gly Asn Gly Thr Thr Cys Lys Ala Phe Cys Lys Asp Gly 
        515                 520                 525             


Cys Arg Asn Gly Gly Ala Cys Ile Ala Ala Asn Val Cys Ala Cys Pro 
    530                 535                 540                 


Gln Gly Phe Thr Gly Pro Ser Cys Glu Thr Asp Ile Asp Glu Cys Ser 
545                 550                 555                 560 


Asp Gly Phe Val Gln Cys Asp Ser Arg Ala Asn Cys Ile Asn Leu Pro 
                565                 570                 575     


Gly Trp Tyr His Cys Glu Cys Arg Asp Gly Tyr His Asp Asn Gly Met 
            580                 585                 590         


Phe Ser Pro Ser Gly Glu Ser Cys Glu Asp Ile Asp Glu Cys Gly Thr 
        595                 600                 605             


Gly Arg His Ser Cys Ala Asn Asp Thr Ile Cys Phe Asn Leu Asp Gly 
    610                 615                 620                 


Gly Tyr Asp Cys Arg Cys Pro His Gly Lys Asn Cys Thr Gly Asp Cys 
625                 630                 635                 640 


Ile His Asp Gly Lys Val Lys His Asn Gly Gln Ile Trp Val Leu Glu 
                645                 650                 655     


Asn Asp Arg Cys Ser Val Cys Ser Cys Gln Asn Gly Phe Val Met Cys 
            660                 665                 670         


Arg Arg Met Val Cys Asp Cys Glu Asn Pro Thr Val Asp Leu Phe Cys 
        675                 680                 685             


Cys Pro Glu Cys Asp Pro Arg Leu Ser Ser Gln Cys Leu His Gln Asn 
    690                 695                 700                 


Gly Glu Thr Leu Tyr Asn Ser Gly Asp Thr Trp Val Gln Asn Cys Gln 
705                 710                 715                 720 


Gln Cys Arg Cys Leu Gln Gly Glu Val Asp Cys Trp Pro Leu Pro Cys 
                725                 730                 735     


Pro Asp Val Glu Cys Glu Phe Ser Ile Leu Pro Glu Asn Glu Cys Cys 
            740                 745                 750         


Pro Arg Cys Val Thr Asp Pro Cys Gln Ala Asp Thr Ile Arg Asn Asp 
        755                 760                 765             


Ile Thr Lys Thr Cys Leu Asp Glu Met Asn Val Val Arg Phe Thr Gly 
    770                 775                 780                 


Ser Ser Trp Ile Lys His Gly Thr Glu Cys Thr Leu Cys Gln Cys Lys 
785                 790                 795                 800 


Asn Gly His Ile Cys Cys Ser Val Asp Pro Gln Cys Leu Gln Glu Leu 
                805                 810                 815     


<210>  2862
<211>  815
<212>  PRT
<213>  homo sapiens

<400>  2862

Met Glu Thr Gly Leu Gly Ala Pro Leu Phe Lys Ala Trp Leu Leu Ile 
1               5                   10                  15      


Ser Val Trp Gly Leu Gly Val Asp Pro Ser Leu Gln Ile Asp Val Leu 
            20                  25                  30          


Thr Glu Leu Glu Leu Gly Glu Ser Thr Thr Gly Val Arg Gln Val Pro 
        35                  40                  45              


Gly Leu His Asn Gly Thr Lys Ala Phe Leu Phe Gln Asp Thr Pro Arg 
    50                  55                  60                  


Ser Ile Lys Ala Ser Thr Ala Thr Ala Glu Gln Phe Phe Gln Lys Leu 
65                  70                  75                  80  


Arg Asn Lys His Glu Phe Thr Ile Leu Val Thr Leu Lys Gln Thr His 
                85                  90                  95      


Leu Asn Ser Gly Val Ile Leu Ser Ile His His Leu Asp His Arg Tyr 
            100                 105                 110         


Leu Glu Leu Glu Ser Ser Gly His Arg Asn Glu Val Arg Leu His Tyr 
        115                 120                 125             


Arg Ser Gly Ser His Arg Pro His Thr Glu Val Phe Pro Tyr Ile Leu 
    130                 135                 140                 


Ala Asp Asp Lys Trp His Lys Leu Ser Leu Ala Ile Ser Ala Ser His 
145                 150                 155                 160 


Leu Ile Leu His Ile Asp Cys Asn Lys Ile Tyr Glu Arg Val Val Glu 
                165                 170                 175     


Lys Pro Ser Thr Asp Leu Pro Leu Gly Thr Thr Phe Trp Leu Gly Gln 
            180                 185                 190         


Arg Asn Asn Ala His Gly Tyr Phe Lys Gly Ile Met Gln Asp Val Gln 
        195                 200                 205             


Leu Leu Val Met Pro Gln Gly Phe Ile Ala Gln Cys Pro Asp Leu Asn 
    210                 215                 220                 


Arg Thr Cys Pro Thr Cys Asn Asp Phe His Gly Leu Val Gln Lys Ile 
225                 230                 235                 240 


Met Glu Leu Gln Asp Ile Leu Ala Lys Thr Ser Ala Lys Leu Ser Arg 
                245                 250                 255     


Ala Glu Gln Arg Met Asn Arg Leu Asp Gln Cys Tyr Cys Glu Arg Thr 
            260                 265                 270         


Cys Thr Met Lys Gly Thr Thr Tyr Arg Glu Phe Glu Ser Trp Ile Asp 
        275                 280                 285             


Gly Cys Lys Asn Cys Thr Cys Leu Asn Gly Thr Ile Gln Cys Glu Thr 
    290                 295                 300                 


Leu Ile Cys Pro Asn Pro Asp Cys Pro Leu Lys Ser Ala Leu Ala Tyr 
305                 310                 315                 320 


Val Asp Gly Lys Cys Cys Lys Glu Cys Lys Ser Ile Cys Gln Phe Gln 
                325                 330                 335     


Gly Arg Thr Tyr Phe Glu Gly Glu Arg Asn Thr Val Tyr Ser Ser Ser 
            340                 345                 350         


Gly Val Cys Val Leu Tyr Glu Cys Lys Asp Gln Thr Met Lys Leu Val 
        355                 360                 365             


Glu Ser Ser Gly Cys Pro Ala Leu Asp Cys Pro Glu Ser His Gln Ile 
    370                 375                 380                 


Thr Leu Ser His Ser Cys Cys Lys Val Cys Lys Gly Tyr Asp Phe Cys 
385                 390                 395                 400 


Ser Glu Arg His Asn Cys Met Glu Asn Ser Ile Cys Arg Asn Leu Asn 
                405                 410                 415     


Asp Arg Ala Val Cys Ser Cys Arg Asp Gly Phe Arg Ala Leu Arg Glu 
            420                 425                 430         


Asp Asn Ala Tyr Cys Glu Asp Ile Asp Glu Cys Ala Glu Gly Arg His 
        435                 440                 445             


Tyr Cys Arg Glu Asn Thr Met Cys Val Asn Thr Pro Gly Ser Phe Met 
    450                 455                 460                 


Cys Ile Cys Lys Thr Gly Tyr Ile Arg Ile Asp Asp Tyr Ser Cys Thr 
465                 470                 475                 480 


Glu His Asp Glu Cys Ile Thr Asn Gln His Asn Cys Asp Glu Asn Ala 
                485                 490                 495     


Leu Cys Phe Asn Thr Val Gly Gly His Asn Cys Val Cys Lys Pro Gly 
            500                 505                 510         


Tyr Thr Gly Asn Gly Thr Thr Cys Lys Ala Phe Cys Lys Asp Gly Cys 
        515                 520                 525             


Arg Asn Gly Gly Ala Cys Ile Ala Ala Asn Val Cys Ala Cys Pro Gln 
    530                 535                 540                 


Gly Phe Thr Gly Pro Ser Cys Glu Thr Asp Ile Asp Glu Cys Ser Asp 
545                 550                 555                 560 


Gly Phe Val Gln Cys Asp Ser Arg Ala Asn Cys Ile Asn Leu Pro Gly 
                565                 570                 575     


Trp Tyr His Cys Glu Cys Arg Asp Gly Tyr His Asp Asn Gly Met Phe 
            580                 585                 590         


Ser Pro Ser Gly Glu Ser Cys Glu Asp Ile Asp Glu Cys Gly Thr Gly 
        595                 600                 605             


Arg His Ser Cys Ala Asn Asp Thr Ile Cys Phe Asn Leu Asp Gly Gly 
    610                 615                 620                 


Tyr Asp Cys Arg Cys Pro His Gly Lys Asn Cys Thr Gly Asp Cys Ile 
625                 630                 635                 640 


His Asp Gly Lys Val Lys His Asn Gly Gln Ile Trp Val Leu Glu Asn 
                645                 650                 655     


Asp Arg Cys Ser Val Cys Ser Cys Gln Asn Gly Phe Val Met Cys Arg 
            660                 665                 670         


Arg Met Val Cys Asp Cys Glu Asn Pro Thr Val Asp Leu Phe Cys Cys 
        675                 680                 685             


Pro Glu Cys Asp Pro Arg Leu Ser Ser Gln Cys Leu His Gln Asn Gly 
    690                 695                 700                 


Glu Thr Leu Tyr Asn Ser Gly Asp Thr Trp Val Gln Asn Cys Gln Gln 
705                 710                 715                 720 


Cys Arg Cys Leu Gln Gly Glu Val Asp Cys Trp Pro Leu Pro Cys Pro 
                725                 730                 735     


Asp Val Glu Cys Glu Phe Ser Ile Leu Pro Glu Asn Glu Cys Cys Pro 
            740                 745                 750         


Arg Cys Val Thr Asp Pro Cys Gln Ala Asp Thr Ile Arg Asn Asp Ile 
        755                 760                 765             


Thr Lys Thr Cys Leu Asp Glu Met Asn Val Val Arg Phe Thr Gly Ser 
    770                 775                 780                 


Ser Trp Ile Lys His Gly Thr Glu Cys Thr Leu Cys Gln Cys Lys Asn 
785                 790                 795                 800 


Gly His Ile Cys Cys Ser Val Asp Pro Gln Cys Leu Gln Glu Leu 
                805                 810                 815 


<210>  2863
<211>  71
<212>  PRT
<213>  homo sapiens

<400>  2863

Met Ala Gly Met Ala Leu Ala Arg Ala Trp Lys Gln Met Ser Trp Phe 
1               5                   10                  15      


Tyr Tyr Gln Tyr Leu Leu Val Thr Ala Leu Tyr Met Leu Glu Pro Trp 
            20                  25                  30          


Glu Arg Thr Val Phe Asn Ser Met Leu Val Ser Ile Val Gly Met Ala 
        35                  40                  45              


Leu Tyr Thr Gly Tyr Val Phe Met Pro Gln His Ile Met Ala Ile Leu 
    50                  55                  60                  


His Tyr Phe Glu Ile Val Gln 
65                  70      


<210>  2864
<211>  227
<212>  PRT
<213>  homo sapiens

<400>  2864

Met Glu Gly Ser Ala Val Thr Val Leu Glu Arg Gly Gly Ala Ser Ser 
1               5                   10                  15      


Pro Ala Glu Arg Arg Ser Lys Arg Arg Arg Arg Ser Gly Gly Asp Gly 
            20                  25                  30          


Gly Gly Gly Gly Gly Ala Arg Ala Pro Glu Gly Val Arg Ala Pro Ala 
        35                  40                  45              


Ala Gly Gln Pro Arg Ala Thr Lys Gly Ala Pro Pro Pro Pro Gly Thr 
    50                  55                  60                  


Pro Pro Pro Ser Pro Met Ser Ser Ala Ile Glu Arg Lys Ser Leu Asp 
65                  70                  75                  80  


Pro Ser Glu Glu Pro Val Asp Glu Val Leu Gln Ile Pro Pro Ser Leu 
                85                  90                  95      


Leu Thr Cys Gly Gly Cys Gln Gln Asn Ile Gly Asp Arg Tyr Phe Leu 
            100                 105                 110         


Lys Ala Ile Asp Gln Tyr Trp His Glu Asp Cys Leu Ser Cys Asp Leu 
        115                 120                 125             


Cys Gly Cys Arg Leu Gly Glu Val Gly Arg Arg Leu Tyr Tyr Lys Leu 
    130                 135                 140                 


Gly Arg Lys Leu Cys Arg Arg Asp Tyr Leu Arg Leu Phe Gly Gln Asp 
145                 150                 155                 160 


Gly Leu Cys Ala Ser Cys Asp Lys Arg Ile Arg Ala Tyr Glu Met Thr 
                165                 170                 175     


Met Arg Val Lys Asp Lys Val Tyr His Leu Glu Cys Phe Lys Cys Ala 
            180                 185                 190         


Ala Cys Gln Lys His Phe Cys Val Gly Asp Arg Tyr Leu Leu Ile Asn 
        195                 200                 205             


Ser Asp Ile Val Cys Glu Gln Asp Ile Tyr Glu Trp Thr Lys Ile Asn 
    210                 215                 220                 


Gly Met Ile 
225         


<210>  2865
<211>  176
<212>  PRT
<213>  homo sapiens

<400>  2865

Met Ala Ala Arg Gly Arg Arg Ala Glu Pro Gln Gly Arg Glu Ala Pro 
1               5                   10                  15      


Gly Pro Ala Gly Gly Gly Gly Gly Gly Ser Arg Trp Ala Glu Ser Gly 
            20                  25                  30          


Ser Gly Thr Ser Pro Glu Ser Gly Asp Glu Glu Val Ser Gly Ala Gly 
        35                  40                  45              


Ser Ser Pro Val Ser Gly Gly Val Asn Leu Phe Ala Asn Asp Gly Ser 
    50                  55                  60                  


Phe Leu Glu Leu Phe Lys Arg Lys Met Glu Glu Glu Gln Arg Gln Arg 
65                  70                  75                  80  


Gln Glu Glu Pro Pro Pro Gly Pro Gln Arg Pro Asp Gln Ser Ala Ala 
                85                  90                  95      


Ala Ala Gly Pro Gly Asp Pro Lys Arg Lys Gly Gly Pro Gly Ser Thr 
            100                 105                 110         


Leu Ser Phe Val Gly Lys Arg Arg Gly Gly Asn Lys Leu Ala Leu Lys 
        115                 120                 125             


Thr Gly Ile Val Ala Lys Lys Gln Lys Thr Glu Asp Glu Val Leu Thr 
    130                 135                 140                 


Ser Lys Gly Asp Ala Trp Ala Lys Tyr Met Ala Glu Val Lys Lys Tyr 
145                 150                 155                 160 


Lys Ala His Gln Cys Gly Asp Asp Asp Lys Thr Arg Pro Leu Val Lys 
                165                 170                 175     


<210>  2866
<211>  902
<212>  PRT
<213>  homo sapiens

<400>  2866

Met Asp Ser Glu Arg Gln Val Lys Asp Thr Asp Asp Ile Glu Ser Pro 
1               5                   10                  15      


Lys Arg Ser Ile Arg Asp Ser Gly Tyr Ile Asp Cys Trp Asp Ser Glu 
            20                  25                  30          


Arg Ser Asp Ser Leu Ser Pro Pro Arg His Gly Arg Asp Asp Ser Phe 
        35                  40                  45              


Asp Ser Leu Asp Ser Phe Gly Ser Arg Ser Arg Gln Thr Pro Ser Pro 
    50                  55                  60                  


Asp Val Val Leu Arg Gly Ser Ser Asp Gly Arg Gly Ser Asp Ser Glu 
65                  70                  75                  80  


Ser Asp Leu Pro His Arg Lys Leu Pro Asp Val Lys Lys Asp Asp Met 
                85                  90                  95      


Ser Ala Arg Arg Thr Ser His Gly Glu Pro Lys Ser Ala Val Pro Phe 
            100                 105                 110         


Asn Gln Tyr Leu Pro Asn Lys Ser Asn Gln Thr Ala Tyr Val Pro Ala 
        115                 120                 125             


Pro Leu Arg Lys Lys Lys Ala Glu Arg Glu Glu Tyr Arg Lys Ser Trp 
    130                 135                 140                 


Ser Thr Ala Thr Ser Pro Leu Gly Gly Glu Arg Pro Phe Arg Tyr Gly 
145                 150                 155                 160 


Pro Arg Thr Pro Val Ser Asp Asp Ala Glu Ser Thr Ser Met Phe Asp 
                165                 170                 175     


Met Arg Cys Glu Glu Glu Ala Ala Val Gln Pro His Ser Arg Ala Arg 
            180                 185                 190         


Gln Glu Gln Leu Gln Leu Ile Asn Asn Gln Leu Arg Glu Glu Asp Asp 
        195                 200                 205             


Lys Trp Gln Asp Asp Leu Ala Arg Trp Lys Ser Arg Arg Arg Ser Val 
    210                 215                 220                 


Ser Gln Asp Leu Ile Lys Lys Glu Glu Glu Arg Lys Lys Met Glu Lys 
225                 230                 235                 240 


Leu Leu Ala Gly Glu Asp Gly Thr Ser Glu Arg Arg Lys Ser Ile Lys 
                245                 250                 255     


Thr Tyr Arg Glu Ile Val Gln Glu Lys Glu Arg Arg Glu Arg Glu Leu 
            260                 265                 270         


His Glu Ala Tyr Lys Asn Ala Arg Ser Gln Glu Glu Ala Glu Gly Ile 
        275                 280                 285             


Leu Gln Gln Tyr Ile Glu Arg Phe Thr Ile Ser Glu Ala Val Leu Glu 
    290                 295                 300                 


Arg Leu Glu Met Pro Lys Ile Leu Glu Arg Ser His Ser Thr Glu Pro 
305                 310                 315                 320 


Asn Leu Ser Ser Phe Leu Asn Asp Pro Asn Pro Met Lys Tyr Leu Arg 
                325                 330                 335     


Gln Gln Ser Leu Pro Pro Pro Lys Phe Thr Ala Thr Val Glu Thr Thr 
            340                 345                 350         


Ile Ala Arg Ala Ser Val Leu Asp Thr Ser Met Ser Ala Gly Ser Gly 
        355                 360                 365             


Ser Pro Ser Lys Thr Val Thr Pro Lys Ala Val Pro Met Leu Thr Pro 
    370                 375                 380                 


Lys Pro Tyr Ser Gln Pro Lys Asn Ser Gln Asp Val Leu Lys Thr Phe 
385                 390                 395                 400 


Lys Val Asp Gly Lys Val Ser Val Asn Gly Glu Thr Val His Arg Glu 
                405                 410                 415     


Glu Glu Lys Glu Arg Glu Cys Pro Thr Val Ala Pro Ala His Ser Leu 
            420                 425                 430         


Thr Lys Ser Gln Met Phe Glu Gly Val Ala Arg Val His Gly Ser Pro 
        435                 440                 445             


Leu Glu Leu Lys Gln Asp Asn Gly Ser Ile Glu Ile Asn Ile Lys Lys 
    450                 455                 460                 


Pro Asn Ser Val Pro Gln Glu Leu Ala Ala Thr Thr Glu Lys Thr Glu 
465                 470                 475                 480 


Pro Asn Ser Gln Glu Asp Lys Asn Asp Gly Gly Lys Ser Arg Lys Gly 
                485                 490                 495     


Asn Ile Glu Leu Ala Ser Ser Glu Pro Gln His Phe Thr Thr Thr Val 
            500                 505                 510         


Thr Arg Cys Ser Pro Thr Val Ala Phe Val Glu Phe Pro Ser Ser Pro 
        515                 520                 525             


Gln Leu Lys Asn Asp Val Ser Glu Glu Lys Asp Gln Lys Lys Pro Glu 
    530                 535                 540                 


Asn Glu Met Ser Gly Lys Val Glu Leu Val Leu Ser Gln Lys Val Val 
545                 550                 555                 560 


Lys Pro Lys Ser Pro Glu Pro Glu Ala Thr Leu Thr Phe Pro Phe Leu 
                565                 570                 575     


Asp Lys Met Pro Glu Ala Asn Gln Leu His Leu Pro Asn Leu Asn Ser 
            580                 585                 590         


Gln Val Asp Ser Pro Ser Ser Glu Lys Ser Pro Val Met Thr Pro Phe 
        595                 600                 605             


Lys Phe Trp Ala Trp Asp Pro Glu Glu Glu Arg Arg Arg Gln Glu Lys 
    610                 615                 620                 


Trp Gln Gln Glu Gln Glu Arg Leu Leu Gln Glu Arg Tyr Gln Lys Glu 
625                 630                 635                 640 


Gln Asp Lys Leu Lys Glu Glu Trp Glu Lys Ala Gln Lys Glu Val Glu 
                645                 650                 655     


Glu Glu Glu Arg Arg Tyr Tyr Glu Glu Glu Arg Lys Ile Ile Glu Asp 
            660                 665                 670         


Thr Val Val Pro Phe Thr Val Ser Ser Ser Ser Ala Asp Gln Leu Ser 
        675                 680                 685             


Thr Ser Ser Ser Met Thr Glu Gly Ser Gly Thr Met Asn Lys Ile Asp 
    690                 695                 700                 


Leu Gly Asn Cys Gln Asp Glu Lys Gln Asp Arg Arg Trp Lys Lys Ser 
705                 710                 715                 720 


Phe Gln Gly Asp Asp Ser Asp Leu Leu Leu Lys Thr Arg Glu Ser Asp 
                725                 730                 735     


Arg Leu Glu Glu Lys Gly Ser Leu Thr Glu Gly Ala Leu Ala His Ser 
            740                 745                 750         


Gly Asn Pro Val Ser Lys Gly Val His Glu Asp His Gln Leu Asp Thr 
        755                 760                 765             


Glu Ala Gly Ala Pro His Cys Gly Thr Asn Pro Gln Leu Ala Gln Asp 
    770                 775                 780                 


Pro Ser Gln Asn Gln Gln Thr Ser Asn Pro Thr His Ser Ser Glu Asp 
785                 790                 795                 800 


Val Lys Pro Lys Thr Leu Pro Leu Asp Lys Ser Ile Asn His Gln Ile 
                805                 810                 815     


Glu Ser Pro Ser Glu Arg Arg Lys Ser Ile Ser Gly Lys Lys Leu Cys 
            820                 825                 830         


Ser Ser Cys Gly Leu Pro Leu Gly Lys Gly Ala Ala Met Ile Ile Glu 
        835                 840                 845             


Thr Leu Asn Leu Tyr Phe His Ile Gln Cys Phe Arg Cys Gly Ile Cys 
    850                 855                 860                 


Lys Gly Gln Leu Gly Asp Ala Val Ser Gly Thr Asp Val Arg Ile Arg 
865                 870                 875                 880 


Asn Gly Leu Leu Asn Cys Asn Asp Cys Tyr Met Arg Ser Arg Ser Ala 
                885                 890                 895     


Gly Gln Pro Thr Thr Leu 
            900         


<210>  2867
<211>  666
<212>  PRT
<213>  homo sapiens

<400>  2867

Met Glu Gln Glu Pro Gln Asn Gly Glu Pro Ala Glu Ile Lys Ile Ile 
1               5                   10                  15      


Arg Glu Ala Tyr Lys Lys Ala Phe Leu Phe Val Asn Lys Gly Leu Asn 
            20                  25                  30          


Thr Asp Glu Leu Gly Gln Lys Glu Glu Ala Lys Asn Tyr Tyr Lys Gln 
        35                  40                  45              


Gly Ile Gly His Leu Leu Arg Gly Ile Ser Ile Ser Ser Lys Glu Ser 
    50                  55                  60                  


Glu His Thr Gly Pro Gly Trp Glu Ser Ala Arg Gln Met Gln Gln Lys 
65                  70                  75                  80  


Met Lys Glu Thr Leu Gln Asn Val Arg Thr Arg Leu Glu Ile Leu Glu 
                85                  90                  95      


Lys Gly Leu Ala Thr Ser Leu Gln Asn Asp Leu Gln Glu Val Pro Lys 
            100                 105                 110         


Leu Tyr Pro Glu Phe Pro Pro Lys Asp Met Cys Glu Lys Leu Pro Glu 
        115                 120                 125             


Pro Gln Ser Phe Ser Ser Ala Pro Gln His Ala Glu Val Asn Gly Asn 
    130                 135                 140                 


Thr Ser Thr Pro Ser Ala Gly Ala Val Ala Ala Pro Ala Ser Leu Ser 
145                 150                 155                 160 


Leu Pro Ser Gln Ser Cys Pro Ala Glu Ala Pro Pro Ala Tyr Thr Pro 
                165                 170                 175     


Gln Ala Ala Glu Gly His Tyr Thr Val Ser Tyr Gly Thr Asp Ser Gly 
            180                 185                 190         


Glu Phe Ser Ser Val Gly Glu Glu Phe Tyr Arg Asn His Ser Gln Pro 
        195                 200                 205             


Pro Pro Leu Glu Thr Leu Gly Leu Asp Ala Asp Glu Leu Ile Leu Ile 
    210                 215                 220                 


Pro Asn Gly Val Gln Ile Phe Phe Val Asn Pro Ala Gly Glu Val Ser 
225                 230                 235                 240 


Ala Pro Ser Tyr Pro Gly Tyr Leu Arg Ile Val Arg Phe Leu Asp Asn 
                245                 250                 255     


Ser Leu Asp Thr Val Leu Asn Arg Pro Pro Gly Phe Leu Gln Val Cys 
            260                 265                 270         


Asp Trp Leu Tyr Pro Leu Val Pro Asp Arg Ser Pro Val Leu Lys Cys 
        275                 280                 285             


Thr Ala Gly Ala Tyr Met Phe Pro Asp Thr Met Leu Gln Ala Ala Gly 
    290                 295                 300                 


Cys Phe Val Gly Val Val Leu Ser Ser Glu Leu Pro Glu Asp Asp Arg 
305                 310                 315                 320 


Glu Leu Phe Glu Asp Leu Leu Arg Gln Met Ser Asp Leu Arg Leu Gln 
                325                 330                 335     


Ala Asn Trp Asn Arg Ala Glu Glu Glu Asn Glu Phe Gln Ile Pro Gly 
            340                 345                 350         


Arg Thr Arg Pro Ser Ser Asp Gln Leu Lys Glu Ala Ser Gly Thr Asp 
        355                 360                 365             


Val Lys Gln Leu Asp Gln Gly Asn Lys Asp Val Arg His Lys Gly Lys 
    370                 375                 380                 


Arg Gly Lys Arg Ala Lys Asp Thr Ser Ser Glu Glu Val Asn Leu Ser 
385                 390                 395                 400 


His Ile Val Pro Cys Glu Pro Val Pro Glu Glu Lys Pro Lys Glu Leu 
                405                 410                 415     


Pro Glu Trp Ser Glu Lys Val Ala His Asn Ile Leu Ser Gly Ala Ser 
            420                 425                 430         


Trp Val Ser Trp Gly Leu Val Lys Gly Ala Glu Ile Thr Gly Lys Ala 
        435                 440                 445             


Ile Gln Lys Gly Ala Ser Lys Leu Arg Glu Arg Ile Gln Pro Glu Glu 
    450                 455                 460                 


Lys Pro Val Glu Val Ser Pro Ala Val Thr Lys Gly Leu Tyr Ile Ala 
465                 470                 475                 480 


Lys Gln Ala Thr Gly Gly Ala Ala Lys Val Ser Gln Phe Leu Val Asp 
                485                 490                 495     


Gly Val Cys Thr Val Ala Asn Cys Val Gly Lys Glu Leu Ala Pro His 
            500                 505                 510         


Val Lys Lys His Gly Ser Lys Leu Val Pro Glu Ser Leu Lys Lys Asp 
        515                 520                 525             


Lys Asp Gly Lys Ser Pro Leu Asp Gly Ala Met Val Val Ala Ala Ser 
    530                 535                 540                 


Ser Val Gln Gly Phe Ser Thr Val Trp Gln Gly Leu Glu Cys Ala Ala 
545                 550                 555                 560 


Lys Cys Ile Val Asn Asn Val Ser Ala Glu Thr Val Gln Thr Val Arg 
                565                 570                 575     


Tyr Lys Tyr Gly Tyr Asn Ala Gly Glu Ala Thr His His Ala Val Asp 
            580                 585                 590         


Ser Ala Val Asn Val Gly Val Thr Ala Tyr Asn Ile Asn Asn Ile Gly 
        595                 600                 605             


Ile Lys Ala Met Val Lys Lys Thr Ala Thr Gln Thr Gly His Thr Leu 
    610                 615                 620                 


Leu Glu Asp Tyr Gln Ile Val Asp Asn Ser Gln Arg Glu Asn Gln Glu 
625                 630                 635                 640 


Gly Ala Ala Asn Val Asn Val Arg Gly Glu Lys Asp Glu Gln Thr Lys 
                645                 650                 655     


Glu Val Lys Glu Ala Lys Lys Lys Asp Lys 
            660                 665     


<210>  2868
<211>  666
<212>  PRT
<213>  homo sapiens

<400>  2868

Met Glu Gln Glu Pro Gln Asn Gly Glu Pro Ala Glu Ile Lys Ile Ile 
1               5                   10                  15      


Arg Glu Ala Tyr Lys Lys Ala Phe Leu Phe Val Asn Lys Gly Leu Asn 
            20                  25                  30          


Thr Asp Glu Leu Gly Gln Lys Glu Glu Ala Lys Asn Tyr Tyr Lys Gln 
        35                  40                  45              


Gly Ile Gly His Leu Leu Arg Gly Ile Ser Ile Ser Ser Lys Glu Ser 
    50                  55                  60                  


Glu His Thr Gly Pro Gly Trp Glu Ser Ala Arg Gln Met Gln Gln Lys 
65                  70                  75                  80  


Met Lys Glu Thr Leu Gln Asn Val Arg Thr Arg Leu Glu Ile Leu Glu 
                85                  90                  95      


Lys Gly Leu Ala Thr Ser Leu Gln Asn Asp Leu Gln Glu Val Pro Lys 
            100                 105                 110         


Leu Tyr Pro Glu Phe Pro Pro Lys Asp Met Cys Glu Lys Leu Pro Glu 
        115                 120                 125             


Pro Gln Ser Phe Ser Ser Ala Pro Gln His Ala Glu Val Asn Gly Asn 
    130                 135                 140                 


Thr Ser Thr Pro Ser Ala Gly Ala Val Ala Ala Pro Ala Ser Leu Ser 
145                 150                 155                 160 


Leu Pro Ser Gln Ser Cys Pro Ala Glu Ala Pro Pro Ala Tyr Thr Pro 
                165                 170                 175     


Gln Ala Ala Glu Gly His Tyr Thr Val Ser Tyr Gly Thr Asp Ser Gly 
            180                 185                 190         


Glu Phe Ser Ser Val Gly Glu Glu Phe Tyr Arg Asn His Ser Gln Pro 
        195                 200                 205             


Pro Pro Leu Glu Thr Leu Gly Leu Asp Ala Asp Glu Leu Ile Leu Ile 
    210                 215                 220                 


Pro Asn Gly Val Gln Ile Phe Phe Val Asn Pro Ala Gly Glu Val Ser 
225                 230                 235                 240 


Ala Pro Ser Tyr Pro Gly Tyr Leu Arg Ile Val Arg Phe Leu Asp Asn 
                245                 250                 255     


Ser Leu Asp Thr Val Leu Asn Arg Pro Pro Gly Phe Leu Gln Val Cys 
            260                 265                 270         


Asp Trp Leu Tyr Pro Leu Val Pro Asp Arg Ser Pro Val Leu Lys Cys 
        275                 280                 285             


Thr Ala Gly Ala Tyr Met Phe Pro Asp Thr Met Leu Gln Ala Ala Gly 
    290                 295                 300                 


Cys Phe Val Gly Val Val Leu Ser Ser Glu Leu Pro Glu Asp Asp Arg 
305                 310                 315                 320 


Glu Leu Phe Glu Asp Leu Leu Arg Gln Met Ser Asp Leu Arg Leu Gln 
                325                 330                 335     


Ala Asn Trp Asn Arg Ala Glu Glu Glu Asn Glu Phe Gln Ile Pro Gly 
            340                 345                 350         


Arg Thr Arg Pro Ser Ser Asp Gln Leu Lys Glu Ala Ser Gly Thr Asp 
        355                 360                 365             


Val Lys Gln Leu Asp Gln Gly Asn Lys Asp Val Arg His Lys Gly Lys 
    370                 375                 380                 


Arg Gly Lys Arg Ala Lys Asp Thr Ser Ser Glu Glu Val Asn Leu Ser 
385                 390                 395                 400 


His Ile Val Pro Cys Glu Pro Val Pro Glu Glu Lys Pro Lys Glu Leu 
                405                 410                 415     


Pro Glu Trp Ser Glu Lys Val Ala His Asn Ile Leu Ser Gly Ala Ser 
            420                 425                 430         


Trp Val Ser Trp Gly Leu Val Lys Gly Ala Glu Ile Thr Gly Lys Ala 
        435                 440                 445             


Ile Gln Lys Gly Ala Ser Lys Leu Arg Glu Arg Ile Gln Pro Glu Glu 
    450                 455                 460                 


Lys Pro Val Glu Val Ser Pro Ala Val Thr Lys Gly Leu Tyr Ile Ala 
465                 470                 475                 480 


Lys Gln Ala Thr Gly Gly Ala Ala Lys Val Ser Gln Phe Leu Val Asp 
                485                 490                 495     


Gly Val Cys Thr Val Ala Asn Cys Val Gly Lys Glu Leu Ala Pro His 
            500                 505                 510         


Val Lys Lys His Gly Ser Lys Leu Val Pro Glu Ser Leu Lys Lys Asp 
        515                 520                 525             


Lys Asp Gly Lys Ser Pro Leu Asp Gly Ala Met Val Val Ala Ala Ser 
    530                 535                 540                 


Ser Val Gln Gly Phe Ser Thr Val Trp Gln Gly Leu Glu Cys Ala Ala 
545                 550                 555                 560 


Lys Cys Ile Val Asn Asn Val Ser Ala Glu Thr Val Gln Thr Val Arg 
                565                 570                 575     


Tyr Lys Tyr Gly Tyr Asn Ala Gly Glu Ala Thr His His Ala Val Asp 
            580                 585                 590         


Ser Ala Val Asn Val Gly Val Thr Ala Tyr Asn Ile Asn Asn Ile Gly 
        595                 600                 605             


Ile Lys Ala Met Val Lys Lys Thr Ala Thr Gln Thr Gly His Thr Leu 
    610                 615                 620                 


Leu Glu Asp Tyr Gln Ile Val Asp Asn Ser Gln Arg Glu Asn Gln Glu 
625                 630                 635                 640 


Gly Ala Ala Asn Val Asn Val Arg Gly Glu Lys Asp Glu Gln Thr Lys 
                645                 650                 655     


Glu Val Lys Glu Ala Lys Lys Lys Asp Lys 
            660                 665     


<210>  2869
<211>  1627
<212>  PRT
<213>  homo sapiens

<400>  2869

Met Arg Leu Trp Ser Trp Val Leu His Leu Gly Leu Leu Ser Ala Ala 
1               5                   10                  15      


Leu Gly Cys Gly Leu Ala Glu Arg Pro Arg Arg Ala Arg Arg Asp Pro 
            20                  25                  30          


Arg Ala Gly Arg Pro Pro Arg Pro Ala Ala Gly Pro Ala Thr Cys Ala 
        35                  40                  45              


Thr Arg Ala Ala Arg Gly Arg Arg Ala Ser Pro Pro Pro Pro Pro Pro 
    50                  55                  60                  


Pro Gly Gly Ala Trp Glu Ala Val Arg Val Pro Arg Arg Arg Gln Gln 
65                  70                  75                  80  


Arg Glu Ala Arg Gly Ala Thr Glu Glu Pro Ser Pro Pro Ser Arg Ala 
                85                  90                  95      


Leu Tyr Phe Ser Gly Arg Gly Glu Gln Leu Arg Leu Arg Ala Asp Leu 
            100                 105                 110         


Glu Leu Pro Arg Asp Ala Phe Thr Leu Gln Val Trp Leu Arg Ala Glu 
        115                 120                 125             


Gly Gly Gln Arg Ser Pro Ala Val Ile Thr Gly Leu Tyr Asp Lys Cys 
    130                 135                 140                 


Ser Tyr Ile Ser Arg Asp Arg Gly Trp Val Val Gly Ile His Thr Ile 
145                 150                 155                 160 


Ser Asp Gln Asp Asn Lys Asp Pro Arg Tyr Phe Phe Ser Leu Lys Thr 
                165                 170                 175     


Asp Arg Ala Arg Gln Val Thr Thr Ile Asn Ala His Arg Ser Tyr Leu 
            180                 185                 190         


Pro Gly Gln Trp Val Tyr Leu Ala Ala Thr Tyr Asp Gly Gln Phe Met 
        195                 200                 205             


Lys Leu Tyr Val Asn Gly Ala Gln Val Ala Thr Ser Gly Glu Gln Val 
    210                 215                 220                 


Gly Gly Ile Phe Ser Pro Leu Thr Gln Lys Cys Lys Val Leu Met Leu 
225                 230                 235                 240 


Gly Gly Ser Ala Leu Asn His Asn Tyr Arg Gly Tyr Ile Glu His Phe 
                245                 250                 255     


Ser Leu Trp Lys Val Ala Arg Thr Gln Arg Glu Ile Leu Ser Asp Met 
            260                 265                 270         


Glu Thr His Gly Ala His Thr Ala Leu Pro Gln Leu Leu Leu Gln Glu 
        275                 280                 285             


Asn Trp Asp Asn Val Lys His Ala Trp Ser Pro Met Lys Asp Gly Ser 
    290                 295                 300                 


Ser Pro Lys Val Glu Phe Ser Asn Ala His Gly Phe Leu Leu Asp Thr 
305                 310                 315                 320 


Ser Leu Glu Pro Pro Leu Cys Gly Gln Thr Leu Cys Asp Asn Thr Glu 
                325                 330                 335     


Val Ile Ala Ser Tyr Asn Gln Leu Ser Ser Phe Arg Gln Pro Lys Val 
            340                 345                 350         


Val Arg Tyr Arg Val Val Asn Leu Tyr Glu Asp Asp His Lys Asn Pro 
        355                 360                 365             


Thr Val Thr Arg Glu Gln Val Asp Phe Gln His His Gln Leu Ala Glu 
    370                 375                 380                 


Ala Phe Lys Gln Tyr Asn Ile Ser Trp Glu Leu Asp Val Leu Glu Val 
385                 390                 395                 400 


Ser Asn Ser Ser Leu Arg Arg Arg Leu Ile Leu Ala Asn Cys Asp Ile 
                405                 410                 415     


Ser Lys Ile Gly Asp Glu Asn Cys Asp Pro Glu Cys Asn His Thr Leu 
            420                 425                 430         


Thr Gly His Asp Gly Gly Asp Cys Arg His Leu Arg His Pro Ala Phe 
        435                 440                 445             


Val Lys Lys Gln His Asn Gly Val Cys Asp Met Asp Cys Asn Tyr Glu 
    450                 455                 460                 


Arg Phe Asn Phe Asp Gly Gly Glu Cys Cys Asp Pro Glu Ile Thr Asn 
465                 470                 475                 480 


Val Thr Gln Thr Cys Phe Asp Pro Asp Ser Pro His Arg Ala Tyr Leu 
                485                 490                 495     


Asp Val Asn Glu Leu Lys Asn Ile Leu Lys Leu Asp Gly Ser Thr His 
            500                 505                 510         


Leu Asn Ile Phe Phe Ala Lys Ser Ser Glu Glu Glu Leu Ala Gly Val 
        515                 520                 525             


Ala Thr Trp Pro Trp Asp Lys Glu Ala Leu Met His Leu Gly Gly Ile 
    530                 535                 540                 


Val Leu Asn Pro Ser Phe Tyr Gly Met Pro Gly His Thr His Thr Met 
545                 550                 555                 560 


Ile His Glu Ile Gly His Ser Leu Gly Leu Tyr His Val Phe Arg Gly 
                565                 570                 575     


Ile Ser Glu Ile Gln Ser Cys Ser Asp Pro Cys Met Glu Thr Glu Pro 
            580                 585                 590         


Ser Phe Glu Thr Gly Asp Leu Cys Asn Asp Thr Asn Pro Ala Pro Lys 
        595                 600                 605             


His Lys Ser Cys Gly Asp Pro Gly Pro Gly Asn Asp Thr Cys Gly Phe 
    610                 615                 620                 


His Ser Phe Phe Asn Thr Pro Tyr Asn Asn Phe Met Ser Tyr Ala Asp 
625                 630                 635                 640 


Asp Asp Cys Thr Asp Ser Phe Thr Pro Asn Gln Val Ala Arg Met His 
                645                 650                 655     


Cys Tyr Leu Asp Leu Val Tyr Gln Gly Trp Gln Pro Ser Arg Lys Pro 
            660                 665                 670         


Ala Pro Val Ala Leu Ala Pro Gln Val Leu Gly His Thr Thr Asp Ser 
        675                 680                 685             


Val Thr Leu Glu Trp Phe Pro Pro Ile Asp Gly His Phe Phe Glu Arg 
    690                 695                 700                 


Glu Leu Gly Ser Ala Cys His Leu Cys Leu Glu Gly Arg Ile Leu Val 
705                 710                 715                 720 


Gln Tyr Ala Ser Asn Ala Ser Ser Pro Met Pro Cys Ser Pro Ser Gly 
                725                 730                 735     


His Trp Ser Pro Arg Glu Ala Glu Gly His Pro Asp Val Glu Gln Pro 
            740                 745                 750         


Cys Lys Ser Ser Val Arg Thr Trp Ser Pro Asn Ser Ala Val Asn Pro 
        755                 760                 765             


His Thr Val Pro Pro Ala Cys Pro Glu Pro Gln Gly Cys Tyr Leu Glu 
    770                 775                 780                 


Leu Glu Phe Leu Tyr Pro Leu Val Pro Glu Ser Leu Thr Ile Trp Val 
785                 790                 795                 800 


Thr Phe Val Ser Thr Asp Trp Asp Ser Ser Gly Ala Val Asn Asp Ile 
                805                 810                 815     


Lys Leu Leu Ala Val Ser Gly Lys Asn Ile Ser Leu Gly Pro Gln Asn 
            820                 825                 830         


Val Phe Cys Asp Val Pro Leu Thr Ile Arg Leu Trp Asp Val Gly Glu 
        835                 840                 845             


Glu Val Tyr Gly Ile Gln Ile Tyr Thr Leu Asp Glu His Leu Glu Ile 
    850                 855                 860                 


Asp Ala Ala Met Leu Thr Ser Thr Ala Asp Thr Pro Leu Cys Leu Gln 
865                 870                 875                 880 


Cys Lys Pro Leu Lys Tyr Lys Val Val Arg Asp Pro Pro Leu Gln Met 
                885                 890                 895     


Asp Val Ala Ser Ile Leu His Leu Asn Arg Lys Phe Val Asp Met Asp 
            900                 905                 910         


Leu Asn Leu Gly Ser Val Tyr Gln Tyr Trp Val Ile Thr Ile Ser Gly 
        915                 920                 925             


Thr Glu Glu Ser Glu Pro Ser Pro Ala Val Thr Tyr Ile His Gly Ser 
    930                 935                 940                 


Gly Tyr Cys Gly Asp Gly Ile Ile Gln Lys Asp Gln Gly Glu Gln Cys 
945                 950                 955                 960 


Asp Asp Met Asn Lys Ile Asn Gly Asp Gly Cys Ser Leu Phe Cys Arg 
                965                 970                 975     


Gln Glu Val Ser Phe Asn Cys Ile Asp Glu Pro Ser Arg Cys Tyr Phe 
            980                 985                 990         


His Asp Gly Asp Gly Val Cys Glu  Glu Phe Glu Gln Lys  Thr Ser Ile 
        995                 1000                 1005             


Lys Asp  Cys Gly Val Tyr Thr  Pro Gln Gly Phe Leu  Asp Gln Trp 
    1010                 1015                 1020             


Ala Ser  Asn Ala Ser Val Ser  His Gln Asp Gln Gln  Cys Pro Gly 
    1025                 1030                 1035             


Trp Val  Ile Ile Gly Gln Pro  Ala Ala Ser Gln Val  Cys Arg Thr 
    1040                 1045                 1050             


Lys Val  Ile Asp Leu Ser Glu  Gly Ile Ser Gln His  Ala Trp Tyr 
    1055                 1060                 1065             


Pro Cys  Thr Ile Ser Tyr Pro  Tyr Ser Gln Leu Ala  Gln Thr Thr 
    1070                 1075                 1080             


Phe Trp  Leu Arg Ala Tyr Phe  Ser Gln Pro Met Val  Ala Ala Ala 
    1085                 1090                 1095             


Val Ile  Val His Leu Val Thr  Asp Gly Thr Tyr Tyr  Gly Asp Gln 
    1100                 1105                 1110             


Lys Gln  Glu Thr Ile Ser Val  Gln Leu Leu Asp Thr  Lys Asp Gln 
    1115                 1120                 1125             


Ser His  Asp Leu Gly Leu His  Val Leu Ser Cys Arg  Asn Asn Pro 
    1130                 1135                 1140             


Leu Ile  Ile Pro Val Val His  Asp Leu Ser Gln Pro  Phe Tyr His 
    1145                 1150                 1155             


Ser Gln  Ala Val Arg Val Ser  Phe Ser Ser Pro Leu  Val Ala Ile 
    1160                 1165                 1170             


Ser Gly  Val Ala Leu Arg Ser  Phe Asp Asn Phe Asp  Pro Val Thr 
    1175                 1180                 1185             


Leu Ser  Ser Cys Gln Arg Gly  Glu Thr Tyr Ser Pro  Ala Glu Gln 
    1190                 1195                 1200             


Ser Cys  Val His Phe Ala Cys  Glu Lys Thr Asp Cys  Pro Glu Leu 
    1205                 1210                 1215             


Ala Val  Glu Asn Ala Ser Leu  Asn Cys Ser Ser Ser  Asp Arg Tyr 
    1220                 1225                 1230             


His Gly  Ala Gln Cys Thr Val  Ser Cys Arg Thr Gly  Tyr Val Leu 
    1235                 1240                 1245             


Gln Ile  Arg Arg Asp Asp Glu  Leu Ile Lys Ser Gln  Thr Gly Pro 
    1250                 1255                 1260             


Ser Val  Thr Val Thr Cys Thr  Glu Gly Lys Trp Asn  Lys Gln Val 
    1265                 1270                 1275             


Ala Cys  Glu Pro Val Asp Cys  Ser Ile Pro Asp His  His Gln Val 
    1280                 1285                 1290             


Tyr Ala  Ala Ser Phe Ser Cys  Pro Glu Gly Thr Thr  Phe Gly Ser 
    1295                 1300                 1305             


Gln Cys  Ser Phe Gln Cys Arg  His Pro Ala Gln Leu  Lys Gly Asn 
    1310                 1315                 1320             


Asn Ser  Leu Leu Thr Cys Met  Glu Asp Gly Leu Trp  Ser Phe Pro 
    1325                 1330                 1335             


Glu Ala  Leu Cys Glu Leu Met  Cys Leu Ala Pro Pro  Pro Val Pro 
    1340                 1345                 1350             


Asn Ala  Asp Leu Gln Thr Ala  Arg Cys Arg Glu Asn  Lys His Lys 
    1355                 1360                 1365             


Val Gly  Ser Phe Cys Lys Tyr  Lys Cys Lys Pro Gly  Tyr His Val 
    1370                 1375                 1380             


Pro Gly  Ser Ser Arg Lys Ser  Lys Lys Arg Ala Phe  Lys Thr Gln 
    1385                 1390                 1395             


Cys Thr  Gln Asp Gly Ser Trp  Gln Glu Gly Ala Cys  Val Pro Val 
    1400                 1405                 1410             


Thr Cys  Asp Pro Pro Pro Pro  Lys Phe His Gly Leu  Tyr Gln Cys 
    1415                 1420                 1425             


Thr Asn  Gly Phe Gln Phe Asn  Ser Glu Cys Arg Ile  Lys Cys Glu 
    1430                 1435                 1440             


Asp Ser  Asp Ala Ser Gln Gly  Leu Gly Ser Asn Val  Ile His Cys 
    1445                 1450                 1455             


Arg Lys  Asp Gly Thr Trp Asn  Gly Ser Phe His Val  Cys Gln Glu 
    1460                 1465                 1470             


Met Gln  Gly Gln Cys Ser Val  Pro Asn Glu Leu Asn  Ser Asn Leu 
    1475                 1480                 1485             


Lys Leu  Gln Cys Pro Asp Gly  Tyr Ala Ile Gly Ser  Glu Cys Ala 
    1490                 1495                 1500             


Thr Ser  Cys Leu Asp His Asn  Ser Glu Ser Ile Ile  Leu Pro Met 
    1505                 1510                 1515             


Asn Val  Thr Val Arg Asp Ile  Pro His Trp Leu Asn  Pro Thr Arg 
    1520                 1525                 1530             


Val Glu  Arg Val Val Cys Thr  Ala Gly Leu Lys Trp  Tyr Pro His 
    1535                 1540                 1545             


Pro Ala  Leu Ile His Cys Val  Lys Gly Cys Glu Pro  Phe Met Gly 
    1550                 1555                 1560             


Asp Asn  Tyr Cys Asp Ala Ile  Asn Asn Arg Ala Phe  Cys Asn Tyr 
    1565                 1570                 1575             


Asp Gly  Gly Asp Cys Cys Thr  Ser Thr Val Lys Thr  Lys Lys Val 
    1580                 1585                 1590             


Thr Pro  Phe Pro Met Ser Cys  Asp Leu Gln Gly Asp  Cys Ala Cys 
    1595                 1600                 1605             


Arg Asp  Pro Gln Ala Gln Glu  His Ser Arg Lys Asp  Leu Arg Gly 
    1610                 1615                 1620             


Tyr Ser  His Gly 
    1625         


<210>  2870
<211>  311
<212>  PRT
<213>  homo sapiens

<400>  2870

Met His Gln Lys Leu Leu Lys Ser Ala His Tyr Ile Glu Leu Gly Ser 
1               5                   10                  15      


Tyr Gln Tyr Trp Pro Val Leu Val Pro Arg Gly Ile Arg Leu Tyr Thr 
            20                  25                  30          


Tyr Glu Gln Ile Pro Gly Ser Leu Lys Asp Asn Pro Tyr Ile Thr Asp 
        35                  40                  45              


Gly Tyr Arg Ala Tyr Leu Pro Ser Arg Leu Cys Ile Lys Ser Leu Phe 
    50                  55                  60                  


Ile Leu Ser Asn Glu Thr Val Asn Ile Trp Ser His Leu Leu Gly Phe 
65                  70                  75                  80  


Phe Leu Phe Phe Thr Leu Gly Ile Tyr Asp Met Thr Ser Val Leu Pro 
                85                  90                  95      


Ser Ala Ser Ala Ser Arg Glu Asp Phe Val Ile Cys Ser Ile Cys Leu 
            100                 105                 110         


Phe Cys Phe Gln Val Cys Met Leu Cys Ser Val Gly Tyr His Leu Phe 
        115                 120                 125             


Ser Cys His Arg Ser Glu Lys Thr Cys Arg Arg Trp Met Ala Leu Asp 
    130                 135                 140                 


Tyr Ala Gly Ile Ser Ile Gly Ile Leu Gly Cys Tyr Val Ser Gly Val 
145                 150                 155                 160 


Phe Tyr Ala Phe Tyr Cys Asn Asn Tyr Trp Arg Gln Val Tyr Leu Ile 
                165                 170                 175     


Thr Val Leu Ala Met Ile Leu Ala Val Phe Phe Ala Gln Ile His Pro 
            180                 185                 190         


Asn Tyr Leu Thr Gln Gln Trp Gln Arg Leu Arg Ser Ile Ile Phe Cys 
        195                 200                 205             


Ser Val Ser Gly Tyr Gly Val Ile Pro Thr Leu His Trp Val Trp Leu 
    210                 215                 220                 


Asn Gly Gly Ile Gly Ala Pro Ile Val Gln Asp Phe Ala Pro Arg Val 
225                 230                 235                 240 


Ile Val Met Tyr Met Ile Ala Leu Leu Ala Phe Leu Phe Tyr Ile Ser 
                245                 250                 255     


Lys Val Pro Glu Arg Tyr Phe Pro Gly Gln Leu Asn Tyr Leu Gly Ser 
            260                 265                 270         


Ser His Gln Ile Trp His Ile Leu Ala Val Val Met Leu Tyr Trp Trp 
        275                 280                 285             


His Gln Ser Thr Val Tyr Val Met Gln Tyr Arg His Ser Lys Pro Cys 
    290                 295                 300                 


Pro Asp Tyr Val Ser His Leu 
305                 310     


<210>  2871
<211>  465
<212>  PRT
<213>  homo sapiens

<400>  2871

Met Arg Lys Gly Ile Gln Pro Ala Leu Glu Gln Tyr Leu Val Thr Ala 
1               5                   10                  15      


Gly Gly Gly Glu Gly Ala Ala Val Val Ala Ala Ala Ala Ala Ala Ser 
            20                  25                  30          


Met Asp Lys Arg Ala Leu Leu Ala Ser Pro Gly Phe Ala Ala Ala Ala 
        35                  40                  45              


Ala Ala Ala Ala Ala Pro Gly Ala Tyr Ile Gln Ile Leu Thr Thr Asn 
    50                  55                  60                  


Thr Ser Thr Thr Ser Cys Ser Ser Ser Leu Gln Ser Gly Ala Val Ala 
65                  70                  75                  80  


Ala Gly Pro Leu Leu Pro Ser Ala Pro Gly Ala Glu Gln Thr Ala Gly 
                85                  90                  95      


Ser Leu Leu Tyr Thr Thr Pro His Gly Pro Ser Ser Arg Ala Gly Leu 
            100                 105                 110         


Leu Gln Gln Pro Pro Ala Leu Gly Arg Gly Gly Ser Gly Gly Gly Gly 
        115                 120                 125             


Gly Pro Pro Ala Lys Arg Arg Leu Glu Leu Gly Glu Ser Gly His Gln 
    130                 135                 140                 


Tyr Leu Ser Asp Gly Leu Lys Thr Pro Lys Gly Lys Gly Arg Ala Ala 
145                 150                 155                 160 


Leu Arg Ser Pro Asp Ser Pro Lys Thr Pro Lys Ser Pro Ser Glu Lys 
                165                 170                 175     


Thr Arg Tyr Asp Thr Ser Leu Gly Leu Leu Thr Lys Lys Phe Ile Gln 
            180                 185                 190         


Leu Leu Ser Gln Ser Pro Asp Gly Val Leu Asp Leu Asn Lys Ala Ala 
        195                 200                 205             


Glu Val Leu Lys Val Gln Lys Arg Arg Ile Tyr Asp Ile Thr Asn Val 
    210                 215                 220                 


Leu Glu Gly Ile His Leu Ile Lys Lys Lys Ser Lys Asn Asn Val Gln 
225                 230                 235                 240 


Trp Met Gly Cys Ser Leu Ser Glu Asp Gly Gly Met Leu Ala Gln Cys 
                245                 250                 255     


Gln Gly Leu Ser Lys Glu Val Thr Glu Leu Ser Gln Glu Glu Lys Lys 
            260                 265                 270         


Leu Asp Glu Leu Ile Gln Ser Cys Thr Leu Asp Leu Lys Leu Leu Thr 
        275                 280                 285             


Glu Asp Ser Glu Asn Gln Arg Leu Ala Tyr Val Thr Tyr Gln Asp Ile 
    290                 295                 300                 


Arg Lys Ile Ser Gly Leu Lys Asp Gln Thr Val Ile Val Val Lys Ala 
305                 310                 315                 320 


Pro Pro Glu Thr Arg Leu Glu Val Pro Asp Ser Ile Glu Ser Leu Gln 
                325                 330                 335     


Ile His Leu Ala Ser Thr Gln Gly Pro Ile Glu Val Tyr Leu Cys Pro 
            340                 345                 350         


Glu Glu Thr Glu Thr His Ser Pro Met Lys Thr Asn Asn Gln Asp His 
        355                 360                 365             


Asn Gly Asn Ile Pro Lys Pro Ala Ser Lys Asp Leu Ala Ser Thr Asn 
    370                 375                 380                 


Ser Gly His Ser Asp Cys Ser Val Ser Met Gly Asn Leu Ser Pro Leu 
385                 390                 395                 400 


Ala Ser Pro Ala Asn Leu Leu Gln Gln Thr Glu Asp Gln Ile Pro Ser 
                405                 410                 415     


Asn Leu Glu Gly Pro Phe Val Asn Leu Leu Pro Pro Leu Leu Gln Glu 
            420                 425                 430         


Asp Tyr Leu Leu Ser Leu Gly Glu Glu Glu Gly Ile Ser Asp Leu Phe 
        435                 440                 445             


Asp Ala Tyr Asp Leu Glu Lys Leu Pro Leu Val Glu Asp Phe Met Cys 
    450                 455                 460                 


Ser 
465 


<210>  2872
<211>  1610
<212>  PRT
<213>  homo sapiens

<400>  2872

Met Lys Lys Glu Gly Ser Ser Gly Ser Phe Arg Leu Gln Pro Asn Thr 
1               5                   10                  15      


Gly Ser Leu Ser Arg Ala Val Ser Trp Ile Asn Phe Ser Ser Leu Ser 
            20                  25                  30          


Arg Gln Thr Lys Arg Leu Phe Arg Ser Asp Gly Glu Leu Ser Val Cys 
        35                  40                  45              


Gly Gln Gln Val Glu Val Asp Asp Glu Asn Trp Ile Tyr Arg Ala Gln 
    50                  55                  60                  


Pro Arg Lys Ala Val Ser Asn Leu Asp Glu Glu Ser Arg Trp Thr Val 
65                  70                  75                  80  


His Tyr Thr Ala Pro Trp His Gln Gln Glu Asn Val Phe Leu Pro Thr 
                85                  90                  95      


Thr Arg Pro Pro Cys Val Glu Asp Leu His Arg Gln Ala Lys Leu Asn 
            100                 105                 110         


Leu Lys Ser Val Leu Arg Glu Cys Asp Lys Leu Arg His Asp Gly Tyr 
        115                 120                 125             


Arg Ser Ser Gln Tyr Tyr Ser Gln Gly Pro Thr Phe Ala Ala Asn Ala 
    130                 135                 140                 


Ser Pro Phe Cys Asp Asp Tyr Gln Asp Glu Asp Glu Glu Thr Asp Gln 
145                 150                 155                 160 


Lys Cys Ser Leu Ser Ser Ser Glu Glu Glu Arg Phe Ile Ser Ile Arg 
                165                 170                 175     


Arg Pro Lys Thr Pro Ala Ser Ser Asp Phe Ser Asp Leu Asn Thr Gln 
            180                 185                 190         


Thr Asn Trp Thr Lys Ser Leu Pro Leu Pro Thr Pro Glu Glu Lys Met 
        195                 200                 205             


Arg Gln Gln Ala Gln Thr Val Gln Ala Asp Val Val Pro Ile Asn Ile 
    210                 215                 220                 


Thr Ala Ser Gly Thr Gly Gln Asp Asp Ala Asp Gly His Ser Val Tyr 
225                 230                 235                 240 


Thr Pro Asp His Tyr Ser Thr Leu Gly Arg Phe Asn Ser Cys Arg Ser 
                245                 250                 255     


Ala Gly Gln Arg Ser Glu Thr Arg Asp Ser Ser Cys Gln Thr Glu Asp 
            260                 265                 270         


Val Lys Val Val Pro Pro Ser Met Arg Arg Ile Arg Ala Gln Lys Gly 
        275                 280                 285             


Gln Gly Ile Ala Ala Gln Met Gly His Phe Ser Gly Ser Ser Gly Asn 
    290                 295                 300                 


Met Ser Val Leu Ser Asp Ser Ala Gly Ile Val Phe Pro Ser Arg Leu 
305                 310                 315                 320 


Asp Ser Asp Ala Gly Phe His Ser Leu Pro Arg Ser Gly Ala Arg Ala 
                325                 330                 335     


Asn Ile Gln Ser Leu Glu Pro Arg Leu Gly Ala Leu Gly Pro Ala Gly 
            340                 345                 350         


Asp Met Asn Gly Thr Phe Leu Tyr Gln Arg Gly His Pro Gln Ala Asp 
        355                 360                 365             


Glu Asn Leu Gly His Leu Gly Gly Ala Ser Gly Thr Gly Thr Leu Leu 
    370                 375                 380                 


Arg Pro Lys Ser Gln Glu Leu Arg His Phe Glu Ser Glu Asn Ile Met 
385                 390                 395                 400 


Ser Pro Ala Cys Val Val Ser Pro His Ala Thr Tyr Ser Thr Ser Ile 
                405                 410                 415     


Ile Pro Asn Ala Thr Leu Ser Ser Ser Ser Glu Val Ile Ala Ile Pro 
            420                 425                 430         


Thr Ala Gln Ser Ala Gly Gln Arg Glu Ser Lys Ser Ser Gly Ser Ser 
        435                 440                 445             


His Ala Arg Ile Lys Ser Arg Asp His Leu Ile Ser Arg His Ala Val 
    450                 455                 460                 


Lys Gly Asp Pro Gln Ser Pro Gly Arg His Trp Asn Glu Gly His Ala 
465                 470                 475                 480 


Thr Ile Leu Ser Gln Asp Leu Asp Pro His Ser Pro Gly Glu Pro Ala 
                485                 490                 495     


Leu Leu Ser Leu Cys Asp Ser Ala Val Pro Leu Asn Ala Pro Ala Asn 
            500                 505                 510         


Arg Glu Asn Gly Ser Gln Ala Met Pro Tyr Asn Cys Arg Asn Asn Leu 
        515                 520                 525             


Ala Phe Pro Ala His Pro Gln Asp Val Asp Gly Lys Ser Glu Ser Ser 
    530                 535                 540                 


Tyr Ser Gly Gly Gly Gly His Ser Ser Ser Glu Pro Trp Glu Tyr Lys 
545                 550                 555                 560 


Ser Ser Gly Asn Gly Arg Ala Ser Pro Leu Lys Pro His Leu Ala Thr 
                565                 570                 575     


Pro Gly Tyr Ser Thr Pro Thr Ser Asn Met Ser Ser Cys Ser Leu Asp 
            580                 585                 590         


Gln Thr Ser Asn Lys Glu Asp Ala Gly Ser Leu Tyr Ser Glu Asp His 
        595                 600                 605             


Asp Gly Tyr Cys Ala Ser Val His Thr Asp Ser Gly His Gly Ser Gly 
    610                 615                 620                 


Asn Leu Cys Asn Ser Ser Asp Gly Phe Gly Asn Pro Arg His Ser Val 
625                 630                 635                 640 


Ile Asn Val Phe Val Gly Arg Ala Gln Lys Asn Gln Gly Asp Arg Ser 
                645                 650                 655     


Asn Tyr Gln Asp Lys Ser Leu Ser Arg Asn Ile Ser Leu Lys Lys Ala 
            660                 665                 670         


Lys Lys Pro Pro Leu Pro Pro Ser Arg Thr Asp Ser Leu Arg Arg Ile 
        675                 680                 685             


Pro Lys Lys Ser Ser Gln Cys Asn Gly Gln Val Leu Asn Glu Ser Leu 
    690                 695                 700                 


Ile Ala Thr Leu Gln His Ser Leu Gln Leu Ser Leu Pro Gly Lys Ser 
705                 710                 715                 720 


Gly Ser Ser Pro Ser Gln Ser Pro Cys Ser Asp Leu Glu Glu Pro Trp 
                725                 730                 735     


Leu Pro Arg Ser Arg Ser Gln Ser Thr Val Ser Ala Gly Ser Ser Met 
            740                 745                 750         


Thr Ser Ala Thr Thr Pro Asn Val Tyr Ser Leu Cys Gly Ala Thr Pro 
        755                 760                 765             


Ser Gln Ser Asp Thr Ser Ser Val Lys Ser Glu Tyr Thr Asp Pro Trp 
    770                 775                 780                 


Gly Tyr Tyr Ile Asp Tyr Thr Gly Met Gln Glu Asp Pro Gly Asn Pro 
785                 790                 795                 800 


Ala Gly Gly Cys Ser Thr Ser Ser Gly Val Pro Thr Gly Asn Gly Pro 
                805                 810                 815     


Val Arg His Val Gln Glu Gly Ser Arg Ala Thr Met Pro Gln Val Pro 
            820                 825                 830         


Gly Gly Ser Val Lys Pro Lys Ile Met Ser Pro Glu Lys Ser His Arg 
        835                 840                 845             


Val Ile Ser Pro Ser Ser Gly Tyr Ser Ser Gln Ser Asn Thr Pro Thr 
    850                 855                 860                 


Ala Leu Thr Pro Val Pro Val Phe Leu Lys Ser Val Ser Pro Ala Asn 
865                 870                 875                 880 


Gly Lys Gly Lys Pro Lys Pro Lys Val Pro Glu Arg Lys Ser Ser Leu 
                885                 890                 895     


Ile Ser Ser Val Ser Ile Ser Ser Ser Ser Thr Ser Leu Ser Ser Ser 
            900                 905                 910         


Thr Ser Thr Glu Gly Ser Gly Thr Met Lys Lys Leu Asp Pro Ala Val 
        915                 920                 925             


Gly Ser Pro Pro Ala Pro Pro Pro Pro Pro Val Pro Ser Pro Pro Phe 
    930                 935                 940                 


Pro Cys Pro Ala Asp Arg Ser Pro Phe Leu Pro Pro Pro Pro Pro Val 
945                 950                 955                 960 


Thr Asp Cys Ser Gln Gly Ser Pro Leu Pro His Ser Pro Val Phe Pro 
                965                 970                 975     


Pro Pro Pro Pro Glu Ala Leu Ile Pro Phe Cys Ser Pro Pro Asp Trp 
            980                 985                 990         


Cys Leu Ser Pro Pro Arg Pro Ala  Leu Ser Pro Ile Leu  Pro Asp Ser 
        995                 1000                 1005             


Pro Val  Ser Leu Pro Leu Pro  Pro Pro Leu Leu Pro  Ser Ser Glu 
    1010                 1015                 1020             


Pro Pro  Pro Ala Pro Pro Leu  Asp Pro Lys Phe Met  Lys Asp Thr 
    1025                 1030                 1035             


Arg Pro  Pro Phe Thr Asn Ser  Gly Gln Pro Glu Ser  Ser Arg Gly 
    1040                 1045                 1050             


Ser Leu  Arg Pro Pro Ser Thr  Lys Glu Glu Thr Ser  Arg Pro Pro 
    1055                 1060                 1065             


Met Pro  Leu Ile Thr Thr Glu  Ala Leu Gln Met Val  Gln Leu Arg 
    1070                 1075                 1080             


Pro Val  Arg Lys Asn Ser Gly  Ala Glu Ala Ala Gln  Leu Ser Glu 
    1085                 1090                 1095             


Arg Thr  Ala Gln Glu Gln Arg  Thr Pro Val Ala Pro  Gln Tyr His 
    1100                 1105                 1110             


Leu Lys  Pro Ser Ala Phe Leu  Lys Ser Arg Asn Ser  Thr Asn Glu 
    1115                 1120                 1125             


Met Glu  Ser Glu Ser Gln Pro  Ala Ser Val Thr Ser  Ser Leu Pro 
    1130                 1135                 1140             


Thr Pro  Ala Lys Ser Ser Ser  Gln Gly Asp His Gly  Ser Ala Ala 
    1145                 1150                 1155             


Glu Arg  Gly Gly Pro Val Ser  Arg Ser Pro Gly Ala  Pro Ser Ala 
    1160                 1165                 1170             


Gly Glu  Ala Glu Ala Arg Pro  Ser Pro Ser Thr Thr  Pro Leu Pro 
    1175                 1180                 1185             


Asp Ser  Ser Pro Ser Arg Lys  Pro Pro Pro Ile Ser  Lys Lys Pro 
    1190                 1195                 1200             


Lys Leu  Phe Leu Val Val Pro  Pro Pro Gln Lys Asp  Phe Ala Val 
    1205                 1210                 1215             


Glu Pro  Ala Glu Asn Val Ser  Glu Ala Leu Arg Ala  Val Pro Ser 
    1220                 1225                 1230             


Pro Thr  Thr Gly Glu Glu Gly  Ser Val His Ser Arg  Glu Ala Lys 
    1235                 1240                 1245             


Glu Ser  Ser Ala Ala Gln Ala  Gly Ser His Ala Thr  His Pro Gly 
    1250                 1255                 1260             


Thr Ser  Val Leu Glu Gly Gly  Ala Ala Gly Ser Met  Ser Pro Ser 
    1265                 1270                 1275             


Arg Val  Glu Ala Asn Val Pro  Met Val Gln Pro Asp  Val Ser Pro 
    1280                 1285                 1290             


Ala Pro  Lys Gln Glu Glu Pro  Ala Glu Asn Ser Ala  Asp Thr Gly 
    1295                 1300                 1305             


Gly Asp  Gly Glu Ser Cys Leu  Ser Gln Gln Asp Gly  Ala Ala Gly 
    1310                 1315                 1320             


Val Pro  Glu Thr Asn Ala Ala  Gly Ser Ser Ser Glu  Ala Cys Asp 
    1325                 1330                 1335             


Phe Leu  Lys Glu Asp Gly Asn  Asp Glu Val Met Thr  Pro Ser Arg 
    1340                 1345                 1350             


Pro Arg  Thr Thr Glu Asp Leu  Phe Ala Ala Ile His  Arg Ser Lys 
    1355                 1360                 1365             


Arg Lys  Val Leu Gly Arg Arg  Asp Ser Asp Asp Asp  His Ser Arg 
    1370                 1375                 1380             


Asn His  Ser Pro Ser Pro Pro  Val Thr Pro Thr Gly  Ala Ala Pro 
    1385                 1390                 1395             


Ser Leu  Ala Ser Pro Lys Gln  Val Gly Ser Ile Gln  Arg Ser Ile 
    1400                 1405                 1410             


Arg Lys  Ser Ser Thr Ser Ser  Asp Asn Phe Lys Ala  Leu Leu Leu 
    1415                 1420                 1425             


Lys Lys  Gly Ser Arg Ser Asp  Thr Ser Ala Arg Met  Ser Ala Ala 
    1430                 1435                 1440             


Glu Met  Leu Lys Asn Thr Asp  Pro Arg Phe Gln Arg  Ser Arg Ser 
    1445                 1450                 1455             


Glu Pro  Ser Pro Asp Ala Pro  Glu Ser Pro Ser Ser  Cys Ser Pro 
    1460                 1465                 1470             


Ser Lys  Asn Arg Arg Ala Gln  Glu Glu Trp Ala Lys  Asn Glu Gly 
    1475                 1480                 1485             


Leu Met  Pro Arg Ser Leu Ser  Phe Ser Gly Pro Arg  Tyr Gly Arg 
    1490                 1495                 1500             


Ser Arg  Thr Pro Pro Ser Ala  Ala Ser Ser Arg Tyr  Ser Met Arg 
    1505                 1510                 1515             


Asn Arg  Ile Gln Ser Ser Pro  Met Thr Val Ile Ser  Glu Gly Glu 
    1520                 1525                 1530             


Gly Glu  Ala Val Glu Pro Val  Asp Ser Ile Ala Arg  Gly Ala Leu 
    1535                 1540                 1545             


Gly Ala  Ala Glu Gly Cys Ser  Leu Asp Gly Leu Ala  Arg Glu Glu 
    1550                 1555                 1560             


Met Asp  Glu Gly Gly Leu Leu  Cys Gly Glu Gly Pro  Ala Ala Ser 
    1565                 1570                 1575             


Leu Gln  Pro Gln Ala Pro Gly  Pro Val Asp Gly Thr  Ala Ser Ala 
    1580                 1585                 1590             


Glu Gly  Arg Glu Pro Ser Pro  Gln Cys Gly Gly Ser  Leu Ser Glu 
    1595                 1600                 1605             


Glu Ser  
    1610 


<210>  2873
<211>  650
<212>  PRT
<213>  homo sapiens

<400>  2873

Met Gly Pro Ala Ser Pro Ala Ala Arg Gly Leu Ser Arg Arg Pro Gly 
1               5                   10                  15      


Gln Pro Pro Leu Pro Leu Leu Leu Pro Leu Leu Leu Leu Leu Leu Arg 
            20                  25                  30          


Ala Gln Pro Ala Ile Gly Ser Leu Ala Gly Gly Ser Pro Gly Ala Ala 
        35                  40                  45              


Glu Ala Pro Gly Ser Ala Gln Val Ala Gly Leu Cys Gly Arg Leu Thr 
    50                  55                  60                  


Leu His Arg Asp Leu Arg Thr Gly Arg Trp Glu Pro Asp Pro Gln Arg 
65                  70                  75                  80  


Ser Arg Arg Cys Leu Arg Asp Pro Gln Arg Val Leu Glu Tyr Cys Arg 
                85                  90                  95      


Gln Met Tyr Pro Glu Leu Gln Ile Ala Arg Val Glu Gln Ala Thr Gln 
            100                 105                 110         


Ala Ile Pro Met Glu Arg Trp Cys Gly Gly Ser Arg Ser Gly Ser Cys 
        115                 120                 125             


Ala His Pro His His Gln Val Val Pro Phe Arg Cys Leu Pro Gly Glu 
    130                 135                 140                 


Phe Val Ser Glu Ala Leu Leu Val Pro Glu Gly Cys Arg Phe Leu His 
145                 150                 155                 160 


Gln Glu Arg Met Asp Gln Cys Glu Ser Ser Thr Arg Arg His Gln Glu 
                165                 170                 175     


Ala Gln Glu Ala Cys Ser Ser Gln Gly Leu Ile Leu His Gly Ser Gly 
            180                 185                 190         


Met Leu Leu Pro Cys Gly Ser Asp Arg Phe Arg Gly Val Glu Tyr Val 
        195                 200                 205             


Cys Cys Pro Pro Pro Gly Thr Pro Asp Pro Ser Gly Thr Ala Val Gly 
    210                 215                 220                 


Asp Pro Ser Thr Arg Ser Trp Pro Pro Gly Ser Arg Val Glu Gly Ala 
225                 230                 235                 240 


Glu Asp Glu Glu Glu Glu Glu Ser Phe Pro Gln Pro Val Asp Asp Tyr 
                245                 250                 255     


Phe Val Glu Pro Pro Gln Ala Glu Glu Glu Glu Glu Thr Val Pro Pro 
            260                 265                 270         


Pro Ser Ser His Thr Leu Ala Val Val Gly Lys Val Thr Pro Thr Pro 
        275                 280                 285             


Arg Pro Thr Asp Gly Val Asp Ile Tyr Phe Gly Met Pro Gly Glu Ile 
    290                 295                 300                 


Ser Glu His Glu Gly Phe Leu Arg Ala Lys Met Asp Leu Glu Glu Arg 
305                 310                 315                 320 


Arg Met Arg Gln Ile Asn Glu Val Met Arg Glu Trp Ala Met Ala Asp 
                325                 330                 335     


Asn Gln Ser Lys Asn Leu Pro Lys Ala Asp Arg Gln Ala Leu Asn Glu 
            340                 345                 350         


His Phe Gln Ser Ile Leu Gln Thr Leu Glu Glu Gln Val Ser Gly Glu 
        355                 360                 365             


Arg Gln Arg Leu Val Glu Thr His Ala Thr Arg Val Ile Ala Leu Ile 
    370                 375                 380                 


Asn Asp Gln Arg Arg Ala Ala Leu Glu Gly Phe Leu Ala Ala Leu Gln 
385                 390                 395                 400 


Ala Asp Pro Pro Gln Ala Glu Arg Val Leu Leu Ala Leu Arg Arg Tyr 
                405                 410                 415     


Leu Arg Ala Glu Gln Lys Glu Gln Arg His Thr Leu Arg His Tyr Gln 
            420                 425                 430         


His Val Ala Ala Val Asp Pro Glu Lys Ala Gln Gln Met Arg Phe Gln 
        435                 440                 445             


Val His Thr His Leu Gln Val Ile Glu Glu Arg Val Asn Gln Ser Leu 
    450                 455                 460                 


Gly Leu Leu Asp Gln Asn Pro His Leu Ala Gln Glu Leu Arg Pro Gln 
465                 470                 475                 480 


Ile Gln Glu Leu Leu His Ser Glu His Leu Gly Pro Ser Glu Leu Glu 
                485                 490                 495     


Ala Pro Ala Pro Gly Gly Ser Ser Glu Asp Lys Gly Gly Leu Gln Pro 
            500                 505                 510         


Pro Asp Ser Lys Asp Asp Thr Pro Met Thr Leu Pro Lys Gly Ser Thr 
        515                 520                 525             


Glu Gln Asp Ala Ala Ser Pro Glu Lys Glu Lys Met Asn Pro Leu Glu 
    530                 535                 540                 


Gln Tyr Glu Arg Lys Val Asn Ala Ser Val Pro Arg Gly Phe Pro Phe 
545                 550                 555                 560 


His Ser Ser Glu Ile Gln Arg Asp Glu Leu Ala Pro Ala Gly Thr Gly 
                565                 570                 575     


Val Ser Arg Glu Ala Val Ser Gly Leu Leu Ile Met Gly Ala Gly Gly 
            580                 585                 590         


Gly Ser Leu Ile Val Leu Ser Met Leu Leu Leu Arg Arg Lys Lys Pro 
        595                 600                 605             


Tyr Gly Ala Ile Ser His Gly Val Val Glu Val Asp Pro Met Leu Thr 
    610                 615                 620                 


Leu Glu Glu Gln Gln Leu Arg Glu Leu Gln Arg His Gly Tyr Glu Asn 
625                 630                 635                 640 


Pro Thr Tyr Arg Phe Leu Glu Glu Arg Pro 
                645                 650 


<210>  2874
<211>  828
<212>  PRT
<213>  homo sapiens

<400>  2874

Met Trp Leu Arg Leu Gly Pro Pro Ser Leu Ser Leu Ser Pro Lys Pro 
1               5                   10                  15      


Thr Val Gly Arg Ser Leu Cys Leu Thr Leu Trp Phe Leu Ser Leu Ala 
            20                  25                  30          


Leu Arg Ala Ser Thr Gln Ala Pro Ala Pro Thr Val Asn Thr His Phe 
        35                  40                  45              


Gly Lys Leu Arg Gly Ala Arg Val Pro Leu Pro Ser Glu Ile Leu Gly 
    50                  55                  60                  


Pro Val Asp Gln Tyr Leu Gly Val Pro Tyr Ala Ala Pro Pro Ile Gly 
65                  70                  75                  80  


Glu Lys Arg Phe Leu Pro Pro Glu Pro Pro Pro Ser Trp Ser Gly Ile 
                85                  90                  95      


Arg Asn Ala Thr His Phe Pro Pro Val Cys Pro Gln Asn Ile His Thr 
            100                 105                 110         


Ala Val Pro Glu Val Met Leu Pro Val Trp Phe Thr Ala Asn Leu Asp 
        115                 120                 125             


Ile Val Ala Thr Tyr Ile Gln Glu Pro Asn Glu Asp Cys Leu Tyr Leu 
    130                 135                 140                 


Asn Val Tyr Val Pro Thr Glu Asp Gly Ser Gly Ala Lys Lys Gln Gly 
145                 150                 155                 160 


Glu Asp Leu Ala Asp Asn Asp Gly Asp Glu Asp Glu Asp Ile Arg Asp 
                165                 170                 175     


Ser Gly Ala Lys Pro Val Met Val Tyr Ile His Gly Gly Ser Tyr Met 
            180                 185                 190         


Glu Gly Thr Gly Asn Met Ile Asp Gly Ser Ile Leu Ala Ser Tyr Gly 
        195                 200                 205             


Asn Val Ile Val Ile Thr Leu Asn Tyr Arg Val Gly Val Leu Gly Phe 
    210                 215                 220                 


Leu Ser Thr Gly Asp Gln Ala Ala Lys Gly Asn Tyr Gly Leu Leu Asp 
225                 230                 235                 240 


Gln Ile Gln Ala Leu Arg Trp Val Ser Glu Asn Ile Ala Phe Phe Gly 
                245                 250                 255     


Gly Asp Pro Arg Arg Ile Thr Val Phe Gly Ser Gly Ile Gly Ala Ser 
            260                 265                 270         


Cys Val Ser Leu Leu Thr Leu Ser His His Ser Glu Gly Leu Phe Gln 
        275                 280                 285             


Arg Ala Ile Ile Gln Ser Gly Ser Ala Leu Ser Ser Trp Ala Val Asn 
    290                 295                 300                 


Tyr Gln Pro Val Lys Tyr Thr Ser Leu Leu Ala Asp Lys Val Gly Cys 
305                 310                 315                 320 


Asn Val Leu Asp Thr Val Asp Met Val Asp Cys Leu Arg Gln Lys Ser 
                325                 330                 335     


Ala Lys Glu Leu Val Glu Gln Asp Ile Gln Pro Ala Arg Tyr His Val 
            340                 345                 350         


Ala Phe Gly Pro Val Ile Asp Gly Asp Val Ile Pro Asp Asp Pro Glu 
        355                 360                 365             


Ile Leu Met Glu Gln Gly Glu Phe Leu Asn Tyr Asp Ile Met Leu Gly 
    370                 375                 380                 


Val Asn Gln Gly Glu Gly Leu Lys Phe Val Glu Gly Val Val Asp Pro 
385                 390                 395                 400 


Glu Asp Gly Val Ser Gly Thr Asp Phe Asp Tyr Ser Val Ser Asn Phe 
                405                 410                 415     


Val Asp Asn Leu Tyr Gly Tyr Pro Glu Gly Lys Asp Thr Leu Arg Glu 
            420                 425                 430         


Thr Ile Lys Phe Met Tyr Thr Asp Trp Ala Asp Arg Asp Asn Pro Glu 
        435                 440                 445             


Thr Arg Arg Lys Thr Leu Val Ala Leu Phe Thr Asp His Gln Trp Val 
    450                 455                 460                 


Glu Pro Ser Val Val Thr Ala Asp Leu His Ala Arg Tyr Gly Ser Pro 
465                 470                 475                 480 


Thr Tyr Phe Tyr Ala Phe Tyr His His Cys Gln Ser Leu Met Lys Pro 
                485                 490                 495     


Ala Trp Ser Asp Ala Ala His Gly Asp Glu Val Pro Tyr Val Phe Gly 
            500                 505                 510         


Val Pro Met Val Gly Pro Thr Asp Leu Phe Pro Cys Asn Phe Ser Lys 
        515                 520                 525             


Asn Asp Val Met Leu Ser Ala Val Val Met Thr Tyr Trp Thr Asn Phe 
    530                 535                 540                 


Ala Lys Thr Gly Asp Pro Asn Lys Pro Val Pro Gln Asp Thr Lys Phe 
545                 550                 555                 560 


Ile His Thr Lys Ala Asn Arg Phe Glu Glu Val Ala Trp Ser Lys Tyr 
                565                 570                 575     


Asn Pro Arg Asp Gln Leu Tyr Leu His Ile Gly Leu Lys Pro Arg Val 
            580                 585                 590         


Arg Asp His Tyr Arg Ala Thr Lys Val Ala Phe Trp Lys His Leu Val 
        595                 600                 605             


Pro His Leu Tyr Asn Leu His Asp Met Phe His Tyr Thr Ser Thr Thr 
    610                 615                 620                 


Thr Lys Val Pro Pro Pro Asp Thr Thr His Ser Ser His Ile Thr Arg 
625                 630                 635                 640 


Arg Pro Asn Gly Lys Thr Trp Ser Thr Lys Arg Pro Ala Ile Ser Pro 
                645                 650                 655     


Ala Tyr Ser Asn Glu Asn Ala Gln Gly Ser Trp Asn Gly Asp Gln Asp 
            660                 665                 670         


Ala Gly Pro Leu Leu Val Glu Asn Pro Arg Asp Tyr Ser Thr Glu Leu 
        675                 680                 685             


Ser Val Thr Ile Ala Val Gly Ala Ser Leu Leu Phe Leu Asn Val Leu 
    690                 695                 700                 


Ala Phe Ala Ala Leu Tyr Tyr Arg Lys Asp Lys Arg Arg Gln Glu Pro 
705                 710                 715                 720 


Leu Arg Gln Pro Ser Pro Gln Arg Gly Ala Gly Ala Pro Glu Leu Gly 
                725                 730                 735     


Ala Ala Pro Glu Glu Glu Leu Ala Ala Leu Gln Leu Gly Pro Thr His 
            740                 745                 750         


His Glu Cys Glu Ala Gly Pro Pro His Asp Thr Leu Arg Leu Thr Ala 
        755                 760                 765             


Leu Pro Asp Tyr Thr Leu Thr Leu Arg Arg Ser Pro Asp Asp Ile Pro 
    770                 775                 780                 


Leu Met Thr Pro Asn Thr Ile Thr Met Ile Pro Asn Ser Leu Val Gly 
785                 790                 795                 800 


Leu Gln Thr Leu His Pro Tyr Asn Thr Phe Ala Ala Gly Phe Asn Ser 
                805                 810                 815     


Thr Gly Leu Pro His Ser His Ser Thr Thr Arg Val 
            820                 825             


<210>  2875
<211>  490
<212>  PRT
<213>  homo sapiens

<400>  2875

Met Ala Asp Thr Arg Ser Val His Glu Thr Arg Phe Glu Ala Ala Val 
1               5                   10                  15      


Lys Val Ile Gln Ser Leu Pro Lys Asn Gly Ser Phe Gln Pro Thr Asn 
            20                  25                  30          


Glu Met Met Leu Lys Phe Tyr Ser Phe Tyr Lys Gln Ala Thr Glu Gly 
        35                  40                  45              


Pro Cys Lys Leu Ser Arg Pro Gly Phe Trp Asp Pro Ile Gly Arg Tyr 
    50                  55                  60                  


Lys Trp Asp Ala Trp Ser Ser Leu Gly Asp Met Thr Lys Glu Glu Ala 
65                  70                  75                  80  


Met Ile Ala Tyr Val Glu Glu Met Lys Lys Ile Ile Glu Thr Met Pro 
                85                  90                  95      


Met Thr Glu Lys Val Glu Glu Leu Leu Arg Val Ile Gly Pro Phe Tyr 
            100                 105                 110         


Glu Ile Val Glu Asp Lys Lys Ser Gly Arg Ser Ser Asp Ile Thr Ser 
        115                 120                 125             


Asp Leu Gly Asn Val Leu Thr Ser Thr Pro Asn Ala Lys Thr Val Asn 
    130                 135                 140                 


Gly Lys Ala Glu Ser Ser Asp Ser Gly Ala Glu Ser Glu Glu Glu Glu 
145                 150                 155                 160 


Ala Gln Glu Glu Val Lys Gly Ala Glu Gln Ser Asp Asn Asp Lys Lys 
                165                 170                 175     


Met Met Lys Lys Ser Ala Asp His Lys Asn Leu Glu Val Ile Val Thr 
            180                 185                 190         


Asn Gly Tyr Asp Lys Asp Gly Phe Val Gln Asp Ile Gln Asn Asp Ile 
        195                 200                 205             


His Ala Ser Ser Ser Leu Asn Gly Arg Ser Thr Glu Glu Val Lys Pro 
    210                 215                 220                 


Ile Asp Glu Asn Leu Gly Gln Thr Gly Lys Ser Ala Val Cys Ile His 
225                 230                 235                 240 


Gln Asp Ile Asn Asp Asp His Val Glu Asp Val Thr Gly Ile Gln His 
                245                 250                 255     


Leu Thr Ser Asp Ser Asp Ser Glu Val Tyr Cys Asp Ser Met Glu Gln 
            260                 265                 270         


Phe Gly Gln Glu Glu Ser Leu Asp Ser Phe Thr Ser Asn Asn Gly Pro 
        275                 280                 285             


Phe Gln Tyr Tyr Leu Gly Gly His Ser Ser Gln Pro Met Glu Asn Ser 
    290                 295                 300                 


Gly Phe Arg Glu Asp Ile Gln Val Pro Pro Gly Asn Gly Asn Ile Gly 
305                 310                 315                 320 


Asn Met Gln Val Val Ala Val Glu Gly Lys Gly Glu Val Lys His Gly 
                325                 330                 335     


Gly Glu Asp Gly Arg Asn Asn Ser Gly Ala Pro His Arg Glu Lys Arg 
            340                 345                 350         


Gly Gly Glu Thr Asp Glu Phe Ser Asn Val Arg Arg Gly Arg Gly His 
        355                 360                 365             


Arg Met Gln His Leu Ser Glu Gly Thr Lys Gly Arg Gln Val Gly Ser 
    370                 375                 380                 


Gly Gly Asp Gly Glu Arg Trp Gly Ser Asp Arg Gly Ser Arg Gly Ser 
385                 390                 395                 400 


Leu Asn Glu Gln Ile Ala Leu Val Leu Met Arg Leu Gln Glu Asp Met 
                405                 410                 415     


Gln Asn Val Leu Gln Arg Leu Gln Lys Leu Glu Thr Leu Thr Ala Leu 
            420                 425                 430         


Gln Ala Lys Ser Ser Thr Ser Thr Leu Gln Thr Ala Pro Gln Pro Thr 
        435                 440                 445             


Ser Gln Arg Pro Ser Trp Trp Pro Phe Glu Met Ser Pro Gly Val Leu 
    450                 455                 460                 


Thr Phe Ala Ile Ile Trp Pro Phe Ile Ala Gln Trp Leu Val Tyr Leu 
465                 470                 475                 480 


Tyr Tyr Gln Arg Arg Arg Arg Lys Leu Asn 
                485                 490 


<210>  2876
<211>  360
<212>  PRT
<213>  homo sapiens

<400>  2876

Met Glu Leu Asp Phe Gly His Phe Asp Glu Arg Asp Lys Thr Ser Arg 
1               5                   10                  15      


Asn Met Arg Gly Ser Arg Met Asn Gly Leu Pro Ser Pro Thr His Ser 
            20                  25                  30          


Ala His Cys Ser Phe Tyr Arg Thr Arg Thr Leu Gln Ala Leu Ser Asn 
        35                  40                  45              


Glu Lys Lys Ala Lys Lys Val Arg Phe Tyr Arg Asn Gly Asp Arg Tyr 
    50                  55                  60                  


Phe Lys Gly Ile Val Tyr Ala Val Ser Ser Asp Arg Phe Arg Ser Phe 
65                  70                  75                  80  


Asp Ala Leu Leu Ala Asp Leu Thr Arg Ser Leu Ser Asp Asn Ile Asn 
                85                  90                  95      


Leu Pro Gln Gly Val Arg Tyr Ile Tyr Thr Ile Asp Gly Ser Arg Lys 
            100                 105                 110         


Ile Gly Ser Met Asp Glu Leu Glu Glu Gly Glu Ser Tyr Val Cys Ser 
        115                 120                 125             


Ser Asp Asn Phe Phe Lys Lys Val Glu Tyr Thr Lys Asn Val Asn Pro 
    130                 135                 140                 


Asn Trp Ser Val Asn Val Lys Thr Ser Ala Asn Met Lys Ala Pro Gln 
145                 150                 155                 160 


Ser Leu Ala Ser Ser Asn Ser Ala Gln Ala Arg Glu Asn Lys Asp Phe 
                165                 170                 175     


Val Arg Pro Lys Leu Val Thr Ile Ile Arg Ser Gly Val Lys Pro Arg 
            180                 185                 190         


Lys Ala Val Arg Val Leu Leu Asn Lys Lys Thr Ala His Ser Phe Glu 
        195                 200                 205             


Gln Val Leu Thr Asp Ile Thr Glu Ala Ile Lys Leu Glu Thr Gly Val 
    210                 215                 220                 


Val Lys Lys Leu Tyr Thr Leu Asp Gly Lys Gln Val Thr Cys Leu His 
225                 230                 235                 240 


Asp Phe Phe Gly Asp Asp Asp Val Phe Ile Ala Cys Gly Pro Glu Lys 
                245                 250                 255     


Phe Arg Tyr Ala Gln Asp Asp Phe Ser Leu Asp Glu Asn Glu Cys Arg 
            260                 265                 270         


Val Met Lys Gly Asn Pro Ser Ala Thr Ala Gly Pro Lys Ala Ser Pro 
        275                 280                 285             


Thr Pro Gln Lys Thr Ser Ala Lys Ser Pro Gly Pro Met Arg Arg Ser 
    290                 295                 300                 


Lys Ser Pro Ala Asp Ser Ala Asn Gly Thr Ser Ser Ser Gln Leu Ser 
305                 310                 315                 320 


Thr Pro Lys Ser Lys Gln Ser Pro Ile Ser Thr Pro Thr Ser Pro Gly 
                325                 330                 335     


Ser Leu Arg Lys His Lys Asp Leu Tyr Leu Pro Leu Ser Leu Asp Asp 
            340                 345                 350         


Ser Asp Ser Leu Gly Asp Ser Met 
        355                 360 


<210>  2877
<211>  525
<212>  PRT
<213>  homo sapiens

<400>  2877

Met Leu Phe Leu Ser Phe His Ala Gly Ser Trp Glu Ser Trp Cys Cys 
1               5                   10                  15      


Cys Cys Leu Ile Pro Ala Asp Arg Pro Trp Asp Arg Gly Gln His Trp 
            20                  25                  30          


Gln Leu Glu Met Ala Asp Thr Arg Ser Val His Glu Thr Arg Phe Glu 
        35                  40                  45              


Ala Ala Val Lys Val Ile Gln Ser Leu Pro Lys Asn Gly Ser Phe Gln 
    50                  55                  60                  


Pro Thr Asn Glu Met Met Leu Lys Phe Tyr Ser Phe Tyr Lys Gln Ala 
65                  70                  75                  80  


Thr Glu Gly Pro Cys Lys Leu Ser Arg Pro Gly Phe Trp Asp Pro Ile 
                85                  90                  95      


Gly Arg Tyr Lys Trp Asp Ala Trp Ser Ser Leu Gly Asp Met Thr Lys 
            100                 105                 110         


Glu Glu Ala Met Ile Ala Tyr Val Glu Glu Met Lys Lys Ile Ile Glu 
        115                 120                 125             


Thr Met Pro Met Thr Glu Lys Val Glu Glu Leu Leu Arg Val Ile Gly 
    130                 135                 140                 


Pro Phe Tyr Glu Ile Val Glu Asp Lys Lys Ser Gly Arg Ser Ser Asp 
145                 150                 155                 160 


Ile Thr Ser Asp Leu Gly Asn Val Leu Thr Ser Thr Pro Asn Ala Lys 
                165                 170                 175     


Thr Val Asn Gly Lys Ala Glu Ser Ser Asp Ser Gly Ala Glu Ser Glu 
            180                 185                 190         


Glu Glu Glu Ala Gln Glu Glu Val Lys Gly Ala Glu Gln Ser Asp Asn 
        195                 200                 205             


Asp Lys Lys Met Met Lys Lys Ser Ala Asp His Lys Asn Leu Glu Val 
    210                 215                 220                 


Ile Val Thr Asn Gly Tyr Asp Lys Asp Gly Phe Val Gln Asp Ile Gln 
225                 230                 235                 240 


Asn Asp Ile His Ala Ser Ser Ser Leu Asn Gly Arg Ser Thr Glu Glu 
                245                 250                 255     


Val Lys Pro Ile Asp Glu Asn Leu Gly Gln Thr Gly Lys Ser Ala Val 
            260                 265                 270         


Cys Ile His Gln Asp Ile Asn Asp Asp His Val Glu Asp Val Thr Gly 
        275                 280                 285             


Ile Gln His Leu Thr Ser Asp Ser Asp Ser Glu Val Tyr Cys Asp Ser 
    290                 295                 300                 


Met Glu Gln Phe Gly Gln Glu Glu Ser Leu Asp Ser Phe Thr Ser Asn 
305                 310                 315                 320 


Asn Gly Pro Phe Gln Tyr Tyr Leu Gly Gly His Ser Ser Gln Pro Met 
                325                 330                 335     


Glu Asn Ser Gly Phe Arg Glu Asp Ile Gln Val Pro Pro Gly Asn Gly 
            340                 345                 350         


Asn Ile Gly Asn Met Gln Val Val Ala Val Glu Gly Lys Gly Glu Val 
        355                 360                 365             


Lys His Gly Gly Glu Asp Gly Arg Asn Asn Ser Gly Ala Pro His Arg 
    370                 375                 380                 


Glu Lys Arg Gly Gly Glu Thr Asp Glu Phe Ser Asn Val Arg Arg Gly 
385                 390                 395                 400 


Arg Gly His Arg Met Gln His Leu Ser Glu Gly Thr Lys Gly Arg Gln 
                405                 410                 415     


Val Gly Ser Gly Gly Asp Gly Glu Arg Trp Gly Ser Asp Arg Gly Ser 
            420                 425                 430         


Arg Gly Ser Leu Asn Glu Gln Ile Ala Leu Val Leu Met Arg Leu Gln 
        435                 440                 445             


Glu Asp Met Gln Asn Val Leu Gln Arg Leu Gln Lys Leu Glu Thr Leu 
    450                 455                 460                 


Thr Ala Leu Gln Ala Lys Ser Ser Thr Ser Thr Leu Gln Thr Ala Pro 
465                 470                 475                 480 


Gln Pro Thr Ser Gln Arg Pro Ser Trp Trp Pro Phe Glu Met Ser Pro 
                485                 490                 495     


Gly Val Leu Thr Phe Ala Ile Ile Trp Pro Phe Ile Ala Gln Trp Leu 
            500                 505                 510         


Val Tyr Leu Tyr Tyr Gln Arg Arg Arg Arg Lys Leu Asn 
        515                 520                 525 


<210>  2878
<211>  656
<212>  PRT
<213>  homo sapiens

<400>  2878

Met Ala Ser Thr Asp Tyr Ser Thr Tyr Ser Gln Ala Ala Ala Gln Gln 
1               5                   10                  15      


Gly Tyr Ser Ala Tyr Thr Ala Gln Pro Thr Gln Gly Tyr Ala Gln Thr 
            20                  25                  30          


Thr Gln Ala Tyr Gly Gln Gln Ser Tyr Gly Thr Tyr Gly Gln Pro Thr 
        35                  40                  45              


Asp Val Ser Tyr Thr Gln Ala Gln Thr Thr Ala Thr Tyr Gly Gln Thr 
    50                  55                  60                  


Ala Tyr Ala Thr Ser Tyr Gly Gln Pro Pro Thr Gly Tyr Thr Thr Pro 
65                  70                  75                  80  


Thr Ala Pro Gln Ala Tyr Ser Gln Pro Val Gln Gly Tyr Gly Thr Gly 
                85                  90                  95      


Ala Tyr Asp Thr Thr Thr Ala Thr Val Thr Thr Thr Gln Ala Ser Tyr 
            100                 105                 110         


Ala Ala Gln Ser Ala Tyr Gly Thr Gln Pro Ala Tyr Pro Ala Tyr Gly 
        115                 120                 125             


Gln Gln Pro Ala Ala Thr Ala Pro Thr Arg Pro Gln Asp Gly Asn Lys 
    130                 135                 140                 


Pro Thr Glu Thr Ser Gln Pro Gln Ser Ser Thr Gly Gly Tyr Asn Gln 
145                 150                 155                 160 


Pro Ser Leu Gly Tyr Gly Gln Ser Asn Tyr Ser Tyr Pro Gln Val Pro 
                165                 170                 175     


Gly Ser Tyr Pro Met Gln Pro Val Thr Ala Pro Pro Ser Tyr Pro Pro 
            180                 185                 190         


Thr Ser Tyr Ser Ser Thr Gln Pro Thr Ser Tyr Asp Gln Ser Ser Tyr 
        195                 200                 205             


Ser Gln Gln Asn Thr Tyr Gly Gln Pro Ser Ser Tyr Gly Gln Gln Ser 
    210                 215                 220                 


Ser Tyr Gly Gln Gln Ser Ser Tyr Gly Gln Gln Pro Pro Thr Ser Tyr 
225                 230                 235                 240 


Pro Pro Gln Thr Gly Ser Tyr Ser Gln Ala Pro Ser Gln Tyr Ser Gln 
                245                 250                 255     


Gln Ser Ser Ser Tyr Gly Gln Gln Ser Ser Phe Arg Gln Asp His Pro 
            260                 265                 270         


Ser Ser Met Gly Val Tyr Gly Gln Glu Ser Gly Gly Phe Ser Gly Pro 
        275                 280                 285             


Gly Glu Asn Arg Ser Met Ser Gly Pro Asp Asn Arg Gly Arg Gly Arg 
    290                 295                 300                 


Gly Gly Phe Asp Arg Gly Gly Met Ser Arg Gly Gly Arg Gly Gly Gly 
305                 310                 315                 320 


Arg Gly Gly Met Gly Ser Ala Gly Glu Arg Gly Gly Phe Asn Lys Pro 
                325                 330                 335     


Gly Gly Pro Met Asp Glu Gly Pro Asp Leu Asp Leu Gly Pro Pro Val 
            340                 345                 350         


Asp Pro Asp Glu Asp Ser Asp Asn Ser Ala Ile Tyr Val Gln Gly Leu 
        355                 360                 365             


Asn Asp Ser Val Thr Leu Asp Asp Leu Ala Asp Phe Phe Lys Gln Cys 
    370                 375                 380                 


Gly Val Val Lys Met Asn Lys Arg Thr Gly Gln Pro Met Ile His Ile 
385                 390                 395                 400 


Tyr Leu Asp Lys Glu Thr Gly Lys Pro Lys Gly Asp Ala Thr Val Ser 
                405                 410                 415     


Tyr Glu Asp Pro Pro Thr Ala Lys Ala Ala Val Glu Trp Phe Asp Gly 
            420                 425                 430         


Lys Asp Phe Gln Gly Ser Lys Leu Lys Val Ser Leu Ala Arg Lys Lys 
        435                 440                 445             


Pro Pro Met Asn Ser Met Arg Gly Gly Leu Pro Pro Arg Glu Gly Arg 
    450                 455                 460                 


Gly Met Pro Pro Pro Leu Arg Gly Gly Pro Gly Gly Pro Gly Gly Pro 
465                 470                 475                 480 


Gly Gly Pro Met Gly Arg Met Gly Gly Arg Gly Gly Asp Arg Gly Gly 
                485                 490                 495     


Phe Pro Pro Arg Gly Pro Arg Gly Ser Arg Gly Asn Pro Ser Gly Gly 
            500                 505                 510         


Gly Asn Val Gln His Arg Ala Gly Asp Trp Gln Cys Pro Asn Pro Gly 
        515                 520                 525             


Cys Gly Asn Gln Asn Phe Ala Trp Arg Thr Glu Cys Asn Gln Cys Lys 
    530                 535                 540                 


Ala Pro Lys Pro Glu Gly Phe Leu Pro Pro Pro Phe Pro Pro Pro Gly 
545                 550                 555                 560 


Gly Asp Arg Gly Arg Gly Gly Pro Gly Gly Met Arg Gly Gly Arg Gly 
                565                 570                 575     


Gly Leu Met Asp Arg Gly Gly Pro Gly Gly Met Phe Arg Gly Gly Arg 
            580                 585                 590         


Gly Gly Asp Arg Gly Gly Phe Arg Gly Gly Arg Gly Met Asp Arg Gly 
        595                 600                 605             


Gly Phe Gly Gly Gly Arg Arg Gly Gly Pro Gly Gly Pro Pro Gly Pro 
    610                 615                 620                 


Leu Met Glu Gln Met Gly Gly Arg Arg Gly Gly Arg Gly Gly Pro Gly 
625                 630                 635                 640 


Lys Met Asp Lys Gly Glu His Arg Gln Glu Arg Arg Asp Arg Pro Tyr 
                645                 650                 655     


<210>  2879
<211>  689
<212>  PRT
<213>  homo sapiens

<400>  2879

Met Ala Ala Arg Thr Leu Gly Arg Gly Val Gly Arg Leu Leu Gly Ser 
1               5                   10                  15      


Leu Arg Gly Leu Ser Gly Gln Pro Ala Arg Pro Pro Cys Gly Val Ser 
            20                  25                  30          


Ala Pro Arg Arg Ala Ala Ser Gly Pro Ser Gly Ser Ala Pro Ala Val 
        35                  40                  45              


Ala Ala Ala Ala Ala Gln Pro Gly Ser Tyr Pro Ala Leu Ser Ala Gln 
    50                  55                  60                  


Ala Ala Arg Glu Pro Ala Ala Phe Trp Gly Pro Leu Ala Arg Asp Thr 
65                  70                  75                  80  


Leu Val Trp Asp Thr Pro Tyr His Thr Val Trp Asp Cys Asp Phe Ser 
                85                  90                  95      


Thr Gly Lys Ile Gly Trp Phe Leu Gly Gly Gln Leu Asn Val Ser Val 
            100                 105                 110         


Asn Cys Leu Asp Gln His Val Arg Lys Ser Pro Glu Ser Val Ala Leu 
        115                 120                 125             


Ile Trp Glu Arg Asp Glu Pro Gly Thr Glu Val Arg Ile Thr Tyr Arg 
    130                 135                 140                 


Glu Leu Leu Glu Thr Thr Cys Arg Leu Ala Asn Thr Leu Lys Arg His 
145                 150                 155                 160 


Gly Val His Arg Gly Asp Arg Val Ala Ile Tyr Met Pro Val Ser Pro 
                165                 170                 175     


Leu Ala Val Ala Ala Met Leu Ala Cys Ala Arg Ile Gly Ala Val His 
            180                 185                 190         


Thr Val Ile Phe Ala Gly Phe Ser Ala Glu Ser Leu Ala Gly Arg Ile 
        195                 200                 205             


Asn Asp Ala Lys Cys Lys Val Val Ile Thr Phe Asn Gln Gly Leu Arg 
    210                 215                 220                 


Gly Gly Arg Val Val Glu Leu Lys Lys Ile Val Asp Glu Ala Val Lys 
225                 230                 235                 240 


His Cys Pro Thr Val Gln His Val Leu Val Ala His Arg Thr Asp Asn 
                245                 250                 255     


Lys Val His Met Gly Asp Leu Asp Val Pro Leu Glu Gln Glu Met Ala 
            260                 265                 270         


Lys Glu Asp Pro Val Cys Ala Pro Glu Ser Met Gly Ser Glu Asp Met 
        275                 280                 285             


Leu Phe Met Leu Tyr Thr Ser Gly Ser Thr Gly Met Pro Lys Gly Ile 
    290                 295                 300                 


Val His Thr Gln Ala Gly Tyr Leu Leu Tyr Ala Ala Leu Thr His Lys 
305                 310                 315                 320 


Leu Val Phe Asp His Gln Pro Gly Asp Ile Phe Gly Cys Val Ala Asp 
                325                 330                 335     


Ile Gly Trp Ile Thr Gly His Ser Tyr Val Val Tyr Gly Pro Leu Cys 
            340                 345                 350         


Asn Gly Ala Thr Ser Val Leu Phe Glu Ser Thr Pro Val Tyr Pro Asn 
        355                 360                 365             


Ala Gly Arg Tyr Trp Glu Thr Val Glu Arg Leu Lys Ile Asn Gln Phe 
    370                 375                 380                 


Tyr Gly Ala Pro Thr Ala Val Arg Leu Leu Leu Lys Tyr Gly Asp Ala 
385                 390                 395                 400 


Trp Val Lys Lys Tyr Asp Arg Ser Ser Leu Arg Thr Leu Gly Ser Val 
                405                 410                 415     


Gly Glu Pro Ile Asn Cys Glu Ala Trp Glu Trp Leu His Arg Val Val 
            420                 425                 430         


Gly Asp Ser Arg Cys Thr Leu Val Asp Thr Trp Trp Gln Thr Glu Thr 
        435                 440                 445             


Gly Gly Ile Cys Ile Ala Pro Arg Pro Ser Glu Glu Gly Ala Glu Ile 
    450                 455                 460                 


Leu Pro Ala Met Ala Met Arg Pro Phe Phe Gly Ile Val Pro Val Leu 
465                 470                 475                 480 


Met Asp Glu Lys Gly Ser Val Val Glu Gly Ser Asn Val Ser Gly Ala 
                485                 490                 495     


Leu Cys Ile Ser Gln Ala Trp Pro Gly Met Ala Arg Thr Ile Tyr Gly 
            500                 505                 510         


Asp His Gln Arg Phe Val Asp Ala Tyr Phe Lys Ala Tyr Pro Gly Tyr 
        515                 520                 525             


Tyr Phe Thr Gly Asp Gly Ala Tyr Arg Thr Glu Gly Gly Tyr Tyr Gln 
    530                 535                 540                 


Ile Thr Gly Arg Met Asp Asp Val Ile Asn Ile Ser Gly His Arg Leu 
545                 550                 555                 560 


Gly Thr Ala Glu Ile Glu Asp Ala Ile Ala Asp His Pro Ala Val Pro 
                565                 570                 575     


Glu Ser Ala Val Ile Gly Tyr Pro His Asp Ile Lys Gly Glu Ala Ala 
            580                 585                 590         


Phe Ala Phe Ile Val Val Lys Asp Ser Ala Gly Asp Ser Asp Val Val 
        595                 600                 605             


Val Gln Glu Leu Lys Ser Met Val Ala Thr Lys Ile Ala Lys Tyr Ala 
    610                 615                 620                 


Val Pro Asp Glu Ile Leu Val Val Lys Arg Leu Pro Lys Thr Arg Ser 
625                 630                 635                 640 


Gly Lys Val Met Arg Arg Leu Leu Arg Lys Ile Ile Thr Ser Glu Ala 
                645                 650                 655     


Gln Glu Leu Gly Asp Thr Thr Thr Leu Glu Asp Pro Ser Ile Ile Ala 
            660                 665                 670         


Glu Ile Leu Ser Val Tyr Gln Lys Cys Lys Asp Lys Gln Ala Ala Ala 
        675                 680                 685             


Lys 
    


<210>  2880
<211>  539
<212>  PRT
<213>  homo sapiens

<400>  2880

Met Asp Cys Gln Leu Ser Ile Leu Leu Leu Leu Ser Cys Ser Val Leu 
1               5                   10                  15      


Asp Ser Phe Gly Glu Leu Ile Pro Gln Pro Ser Asn Glu Val Asn Leu 
            20                  25                  30          


Leu Asp Ser Lys Thr Ile Gln Gly Glu Leu Gly Trp Ile Ser Tyr Pro 
        35                  40                  45              


Ser His Gly Trp Glu Glu Ile Ser Gly Val Asp Glu His Tyr Thr Pro 
    50                  55                  60                  


Ile Arg Thr Tyr Gln Val Cys Asn Val Met Asp His Ser Gln Asn Asn 
65                  70                  75                  80  


Trp Leu Arg Thr Asn Trp Val Pro Arg Asn Ser Ala Gln Lys Ile Tyr 
                85                  90                  95      


Val Glu Leu Lys Phe Thr Leu Arg Asp Cys Asn Ser Ile Pro Leu Val 
            100                 105                 110         


Leu Gly Thr Cys Lys Glu Thr Phe Asn Leu Tyr Tyr Met Glu Ser Asp 
        115                 120                 125             


Asp Asp His Gly Val Lys Phe Arg Glu His Gln Phe Thr Lys Ile Asp 
    130                 135                 140                 


Thr Ile Ala Ala Asp Glu Ser Phe Thr Gln Met Asp Leu Gly Asp Arg 
145                 150                 155                 160 


Ile Leu Lys Leu Asn Thr Glu Ile Arg Glu Val Gly Pro Val Asn Lys 
                165                 170                 175     


Lys Gly Phe Tyr Leu Ala Phe Gln Asp Val Gly Ala Cys Val Ala Leu 
            180                 185                 190         


Val Ser Val Arg Val Tyr Phe Lys Lys Cys Pro Phe Thr Val Lys Asn 
        195                 200                 205             


Leu Ala Met Phe Pro Asp Thr Val Pro Met Asp Ser Gln Ser Leu Val 
    210                 215                 220                 


Glu Val Arg Gly Ser Cys Val Asn Asn Ser Lys Glu Glu Asp Pro Pro 
225                 230                 235                 240 


Arg Met Tyr Cys Ser Thr Glu Gly Glu Trp Leu Val Pro Ile Gly Lys 
                245                 250                 255     


Cys Ser Cys Asn Ala Gly Tyr Glu Glu Arg Gly Phe Met Cys Gln Ala 
            260                 265                 270         


Cys Arg Pro Gly Phe Tyr Lys Ala Leu Asp Gly Asn Met Lys Cys Ala 
        275                 280                 285             


Lys Cys Pro Pro His Ser Ser Thr Gln Glu Asp Gly Ser Met Asn Cys 
    290                 295                 300                 


Arg Cys Glu Asn Asn Tyr Phe Arg Ala Asp Lys Asp Pro Pro Ser Met 
305                 310                 315                 320 


Ala Cys Thr Arg Pro Pro Ser Ser Pro Arg Asn Val Ile Ser Asn Ile 
                325                 330                 335     


Asn Glu Thr Ser Val Ile Leu Asp Trp Ser Trp Pro Leu Asp Thr Gly 
            340                 345                 350         


Gly Arg Lys Asp Val Thr Phe Asn Ile Ile Cys Lys Lys Cys Gly Trp 
        355                 360                 365             


Asn Ile Lys Gln Cys Glu Pro Cys Ser Pro Asn Val Arg Phe Leu Pro 
    370                 375                 380                 


Arg Gln Phe Gly Leu Thr Asn Thr Thr Val Thr Val Thr Asp Leu Leu 
385                 390                 395                 400 


Ala His Thr Asn Tyr Thr Phe Glu Ile Asp Ala Val Asn Gly Val Ser 
                405                 410                 415     


Glu Leu Ser Ser Pro Pro Arg Gln Phe Ala Ala Val Ser Ile Thr Thr 
            420                 425                 430         


Asn Gln Ala Ala Pro Ser Pro Val Leu Thr Ile Lys Lys Asp Arg Thr 
        435                 440                 445             


Ser Arg Asn Ser Ile Ser Leu Ser Trp Gln Glu Pro Glu His Pro Asn 
    450                 455                 460                 


Gly Ile Ile Leu Asp Tyr Glu Val Lys Tyr Tyr Glu Lys Gln Glu Gln 
465                 470                 475                 480 


Glu Thr Ser Tyr Thr Ile Leu Arg Ala Arg Gly Thr Asn Val Thr Ile 
                485                 490                 495     


Ser Ser Leu Lys Pro Asp Thr Ile Tyr Val Phe Gln Ile Arg Ala Arg 
            500                 505                 510         


Thr Ala Ala Gly Tyr Gly Thr Asn Ser Arg Lys Phe Glu Phe Glu Thr 
        515                 520                 525             


Ser Pro Asp Cys Met Tyr Tyr Phe Asn Ala Val 
    530                 535                 


<210>  2881
<211>  227
<212>  PRT
<213>  homo sapiens

<400>  2881

Met Phe Lys Arg Met Ala Glu Phe Gly Pro Asp Ser Gly Gly Arg Val 
1               5                   10                  15      


Lys Gly Val Thr Ile Val Lys Pro Ile Val Tyr Gly Asn Val Ala Arg 
            20                  25                  30          


Tyr Phe Gly Lys Lys Arg Glu Glu Asp Gly His Thr His Gln Trp Thr 
        35                  40                  45              


Val Tyr Val Lys Pro Tyr Arg Asn Glu Asp Met Ser Ala Tyr Val Lys 
    50                  55                  60                  


Lys Ile Gln Phe Lys Leu His Glu Ser Tyr Gly Asn Pro Leu Arg Val 
65                  70                  75                  80  


Val Thr Lys Pro Pro Tyr Glu Ile Thr Glu Thr Gly Trp Gly Glu Phe 
                85                  90                  95      


Glu Ile Ile Ile Lys Ile Phe Phe Ile Asp Pro Asn Glu Arg Pro Val 
            100                 105                 110         


Thr Leu Tyr His Leu Leu Lys Leu Phe Gln Ser Asp Thr Asn Ala Met 
        115                 120                 125             


Leu Gly Lys Lys Thr Val Val Ser Glu Phe Tyr Asp Glu Met Ile Phe 
    130                 135                 140                 


Gln Asp Pro Thr Ala Met Met Gln Gln Leu Leu Thr Thr Ser Arg Gln 
145                 150                 155                 160 


Leu Thr Leu Gly Ala Tyr Lys His Glu Thr Glu Phe Ala Glu Leu Glu 
                165                 170                 175     


Val Lys Thr Arg Glu Lys Leu Glu Ala Ala Lys Lys Lys Thr Ser Phe 
            180                 185                 190         


Glu Ile Ala Glu Leu Lys Glu Arg Leu Lys Ala Ser Arg Glu Thr Ile 
        195                 200                 205             


Asn Cys Leu Lys Asn Glu Ile Arg Lys Leu Glu Glu Asp Asp Gln Ala 
    210                 215                 220                 


Lys Asp Ile 
225         


<210>  2882
<211>  157
<212>  PRT
<213>  homo sapiens

<400>  2882

Met Cys Val Ala Gln Val Leu Thr Ala His Leu Leu Pro Pro Arg Gln 
1               5                   10                  15      


Ala Leu Gly Ser Leu Cys Ser Pro Trp Ala Ala Pro Arg Val Gly Pro 
            20                  25                  30          


Leu Pro Pro Ala Pro Ala Met Val Arg Ile Ser Lys Pro Lys Thr Phe 
        35                  40                  45              


Gln Ala Tyr Leu Asp Asp Cys His Arg Arg Tyr Ser Cys Ala His Cys 
    50                  55                  60                  


Arg Ala His Leu Ala Asn His Asp Asp Leu Ile Ser Lys Ser Phe Gln 
65                  70                  75                  80  


Gly Ser Gln Gly Arg Ala Tyr Leu Phe Asn Ser Val Val Asn Val Gly 
                85                  90                  95      


Cys Gly Pro Ala Glu Glu Arg Val Leu Leu Thr Gly Leu His Ala Val 
            100                 105                 110         


Ala Asp Ile His Cys Glu Asn Cys Lys Thr Thr Leu Gly Trp Lys Tyr 
        115                 120                 125             


Glu Gln Ala Phe Glu Ser Ser Gln Lys Tyr Lys Glu Gly Lys Tyr Ile 
    130                 135                 140                 


Ile Glu Leu Asn His Met Ile Lys Asp Asn Gly Trp Asp 
145                 150                 155         


<210>  2883
<211>  377
<212>  PRT
<213>  homo sapiens

<400>  2883

Met Cys Glu Glu Glu Asp Ser Thr Ala Leu Val Cys Asp Asn Gly Ser 
1               5                   10                  15      


Gly Leu Cys Lys Ala Gly Phe Ala Gly Asp Asp Ala Pro Arg Ala Val 
            20                  25                  30          


Phe Pro Ser Ile Val Gly Arg Pro Arg His Gln Gly Val Met Val Gly 
        35                  40                  45              


Met Gly Gln Lys Asp Ser Tyr Val Gly Asp Glu Ala Gln Ser Lys Arg 
    50                  55                  60                  


Gly Ile Leu Thr Leu Lys Tyr Pro Ile Glu His Gly Ile Ile Thr Asn 
65                  70                  75                  80  


Trp Asp Asp Met Glu Lys Ile Trp His His Ser Phe Tyr Asn Glu Leu 
                85                  90                  95      


Arg Val Ala Pro Glu Glu His Pro Thr Leu Leu Thr Glu Ala Pro Leu 
            100                 105                 110         


Asn Pro Lys Ala Asn Arg Glu Lys Met Thr Gln Ile Met Phe Glu Thr 
        115                 120                 125             


Phe Asn Val Pro Ala Met Tyr Val Ala Ile Gln Ala Val Leu Ser Leu 
    130                 135                 140                 


Tyr Ala Ser Gly Arg Thr Thr Gly Ile Val Leu Asp Ser Gly Asp Gly 
145                 150                 155                 160 


Val Thr His Asn Val Pro Ile Tyr Glu Gly Tyr Ala Leu Pro His Ala 
                165                 170                 175     


Ile Met Arg Leu Asp Leu Ala Gly Arg Asp Leu Thr Asp Tyr Leu Met 
            180                 185                 190         


Lys Ile Leu Thr Glu Arg Gly Tyr Ser Phe Val Thr Thr Ala Glu Arg 
        195                 200                 205             


Glu Ile Val Arg Asp Ile Lys Glu Lys Leu Cys Tyr Val Ala Leu Asp 
    210                 215                 220                 


Phe Glu Asn Glu Met Ala Thr Ala Ala Ser Ser Ser Ser Leu Glu Lys 
225                 230                 235                 240 


Ser Tyr Glu Leu Pro Asp Gly Gln Val Ile Thr Ile Gly Asn Glu Arg 
                245                 250                 255     


Phe Arg Cys Pro Glu Thr Leu Phe Gln Pro Ser Phe Ile Gly Met Glu 
            260                 265                 270         


Ser Ala Gly Ile His Glu Thr Thr Tyr Asn Ser Ile Met Lys Cys Asp 
        275                 280                 285             


Ile Asp Ile Arg Lys Asp Leu Tyr Ala Asn Asn Val Leu Ser Gly Gly 
    290                 295                 300                 


Thr Thr Met Tyr Pro Gly Ile Ala Asp Arg Met Gln Lys Glu Ile Thr 
305                 310                 315                 320 


Ala Leu Ala Pro Ser Thr Met Lys Ile Lys Ile Ile Ala Pro Pro Glu 
                325                 330                 335     


Arg Lys Tyr Ser Val Trp Ile Gly Gly Ser Ile Leu Ala Ser Leu Ser 
            340                 345                 350         


Thr Phe Gln Gln Met Trp Ile Ser Lys Gln Glu Tyr Asp Glu Ala Gly 
        355                 360                 365             


Pro Ser Ile Val His Arg Lys Cys Phe 
    370                 375         


<210>  2884
<211>  262
<212>  PRT
<213>  homo sapiens

<400>  2884

Met Ala Ala Ala Ser Ala Gly Ala Thr Arg Leu Leu Leu Leu Leu Leu 
1               5                   10                  15      


Met Ala Val Ala Ala Pro Ser Arg Ala Arg Gly Ser Gly Cys Arg Ala 
            20                  25                  30          


Gly Thr Gly Ala Arg Gly Ala Gly Ala Glu Gly Arg Glu Gly Glu Ala 
        35                  40                  45              


Cys Gly Thr Val Gly Leu Leu Leu Glu His Ser Phe Glu Ile Asp Asp 
    50                  55                  60                  


Ser Ala Asn Phe Arg Lys Arg Gly Ser Leu Leu Trp Asn Gln Gln Asp 
65                  70                  75                  80  


Gly Thr Leu Ser Leu Ser Gln Arg Gln Leu Ser Glu Glu Glu Arg Gly 
                85                  90                  95      


Arg Leu Arg Asp Val Ala Ala Leu Asn Gly Leu Tyr Arg Val Arg Ile 
            100                 105                 110         


Pro Arg Arg Pro Gly Ala Leu Asp Gly Leu Glu Ala Gly Gly Tyr Val 
        115                 120                 125             


Ser Ser Phe Val Pro Ala Cys Ser Leu Val Glu Ser His Leu Ser Asp 
    130                 135                 140                 


Gln Leu Thr Leu His Val Asp Val Ala Gly Asn Val Val Gly Val Ser 
145                 150                 155                 160 


Val Val Thr His Pro Gly Gly Cys Arg Gly His Glu Val Glu Asp Val 
                165                 170                 175     


Asp Leu Glu Leu Phe Asn Thr Ser Val Gln Leu Gln Pro Pro Thr Thr 
            180                 185                 190         


Ala Pro Gly Pro Glu Thr Ala Ala Phe Ile Glu Arg Leu Glu Met Glu 
        195                 200                 205             


Gln Ala Gln Lys Ala Lys Asn Pro Gln Glu Gln Lys Ser Phe Phe Ala 
    210                 215                 220                 


Lys Tyr Trp Met Tyr Ile Ile Pro Val Val Leu Phe Leu Met Met Ser 
225                 230                 235                 240 


Gly Ala Pro Asp Thr Gly Gly Gln Gly Gly Gly Gly Gly Gly Gly Gly 
                245                 250                 255     


Gly Gly Gly Ser Gly Arg 
            260         


<210>  2885
<211>  706
<212>  PRT
<213>  homo sapiens

<400>  2885

Met Ala Ser Pro Ala Asp Ser Cys Ile Gln Phe Thr Arg His Ala Ser 
1               5                   10                  15      


Asp Val Leu Leu Asn Leu Asn Arg Leu Arg Ser Arg Asp Ile Leu Thr 
            20                  25                  30          


Asp Val Val Ile Val Val Ser Arg Glu Gln Phe Arg Ala His Lys Thr 
        35                  40                  45              


Val Leu Met Ala Cys Ser Gly Leu Phe Tyr Ser Ile Phe Thr Asp Gln 
    50                  55                  60                  


Leu Lys Cys Asn Leu Ser Val Ile Asn Leu Asp Pro Glu Ile Asn Pro 
65                  70                  75                  80  


Glu Gly Phe Cys Ile Leu Leu Asp Phe Met Tyr Thr Ser Arg Leu Asn 
                85                  90                  95      


Leu Arg Glu Gly Asn Ile Met Ala Val Met Ala Thr Ala Met Tyr Leu 
            100                 105                 110         


Gln Met Glu His Val Val Asp Thr Cys Arg Lys Phe Ile Lys Ala Ser 
        115                 120                 125             


Glu Ala Glu Met Val Ser Ala Ile Lys Pro Pro Arg Glu Glu Phe Leu 
    130                 135                 140                 


Asn Ser Arg Met Leu Met Pro Gln Asp Ile Met Ala Tyr Arg Gly Arg 
145                 150                 155                 160 


Glu Val Val Glu Asn Asn Leu Pro Leu Arg Ser Ala Pro Gly Cys Glu 
                165                 170                 175     


Ser Arg Ala Phe Ala Pro Ser Leu Tyr Ser Gly Leu Ser Thr Pro Pro 
            180                 185                 190         


Ala Ser Tyr Ser Met Tyr Ser His Leu Pro Val Ser Ser Leu Leu Phe 
        195                 200                 205             


Ser Asp Glu Glu Phe Arg Asp Val Arg Met Pro Val Ala Asn Pro Phe 
    210                 215                 220                 


Pro Lys Glu Arg Ala Leu Pro Cys Asp Ser Ala Arg Pro Val Pro Gly 
225                 230                 235                 240 


Glu Tyr Ser Arg Pro Thr Leu Glu Val Ser Pro Asn Val Cys His Ser 
                245                 250                 255     


Asn Ile Tyr Ser Pro Lys Glu Thr Ile Pro Glu Glu Ala Arg Ser Asp 
            260                 265                 270         


Met His Tyr Ser Val Ala Glu Gly Leu Lys Pro Ala Ala Pro Ser Ala 
        275                 280                 285             


Arg Asn Ala Pro Tyr Phe Pro Cys Asp Lys Ala Ser Lys Glu Glu Glu 
    290                 295                 300                 


Arg Pro Ser Ser Glu Asp Glu Ile Ala Leu His Phe Glu Pro Pro Asn 
305                 310                 315                 320 


Ala Pro Leu Asn Arg Lys Gly Leu Val Ser Pro Gln Ser Pro Gln Lys 
                325                 330                 335     


Ser Asp Cys Gln Pro Asn Ser Pro Thr Glu Ser Cys Ser Ser Lys Asn 
            340                 345                 350         


Ala Cys Ile Leu Gln Ala Ser Gly Ser Pro Pro Ala Lys Ser Pro Thr 
        355                 360                 365             


Asp Pro Lys Ala Cys Asn Trp Lys Lys Tyr Lys Phe Ile Val Leu Asn 
    370                 375                 380                 


Ser Leu Asn Gln Asn Ala Lys Pro Glu Gly Pro Glu Gln Ala Glu Leu 
385                 390                 395                 400 


Gly Arg Leu Ser Pro Arg Ala Tyr Thr Ala Pro Pro Ala Cys Gln Pro 
                405                 410                 415     


Pro Met Glu Pro Glu Asn Leu Asp Leu Gln Ser Pro Thr Lys Leu Ser 
            420                 425                 430         


Ala Ser Gly Glu Asp Ser Thr Ile Pro Gln Ala Ser Arg Leu Asn Asn 
        435                 440                 445             


Ile Val Asn Arg Ser Met Thr Gly Ser Pro Arg Ser Ser Ser Glu Ser 
    450                 455                 460                 


His Ser Pro Leu Tyr Met His Pro Pro Lys Cys Thr Ser Cys Gly Ser 
465                 470                 475                 480 


Gln Ser Pro Gln His Ala Glu Met Cys Leu His Thr Ala Gly Pro Thr 
                485                 490                 495     


Phe Pro Glu Glu Met Gly Glu Thr Gln Ser Glu Tyr Ser Asp Ser Ser 
            500                 505                 510         


Cys Glu Asn Gly Ala Phe Phe Cys Asn Glu Cys Asp Cys Arg Phe Ser 
        515                 520                 525             


Glu Glu Ala Ser Leu Lys Arg His Thr Leu Gln Thr His Ser Asp Lys 
    530                 535                 540                 


Pro Tyr Lys Cys Asp Arg Cys Gln Ala Ser Phe Arg Tyr Lys Gly Asn 
545                 550                 555                 560 


Leu Ala Ser His Lys Thr Val His Thr Gly Glu Lys Pro Tyr Arg Cys 
                565                 570                 575     


Asn Ile Cys Gly Ala Gln Phe Asn Arg Pro Ala Asn Leu Lys Thr His 
            580                 585                 590         


Thr Arg Ile His Ser Gly Glu Lys Pro Tyr Lys Cys Glu Thr Cys Gly 
        595                 600                 605             


Ala Arg Phe Val Gln Val Ala His Leu Arg Ala His Val Leu Ile His 
    610                 615                 620                 


Thr Gly Glu Lys Pro Tyr Pro Cys Glu Ile Cys Gly Thr Arg Phe Arg 
625                 630                 635                 640 


His Leu Gln Thr Leu Lys Ser His Leu Arg Ile His Thr Gly Glu Lys 
                645                 650                 655     


Pro Tyr His Cys Glu Lys Cys Asn Leu His Phe Arg His Lys Ser Gln 
            660                 665                 670         


Leu Arg Leu His Leu Arg Gln Lys His Gly Ala Ile Thr Asn Thr Lys 
        675                 680                 685             


Val Gln Tyr Arg Val Ser Ala Thr Asp Leu Pro Pro Glu Leu Pro Lys 
    690                 695                 700                 


Ala Cys 
705     


<210>  2886
<211>  295
<212>  PRT
<213>  homo sapiens

<400>  2886

Met Trp Gly Ala Arg Arg Ser Ser Val Ser Ser Ser Trp Asn Ala Ala 
1               5                   10                  15      


Ser Leu Leu Gln Leu Leu Leu Ala Ala Leu Leu Ala Ala Gly Ala Arg 
            20                  25                  30          


Ala Ser Gly Glu Tyr Cys His Gly Trp Leu Asp Ala Gln Gly Val Trp 
        35                  40                  45              


Arg Ile Gly Phe Gln Cys Pro Glu Arg Phe Asp Gly Gly Asp Ala Thr 
    50                  55                  60                  


Ile Cys Cys Gly Ser Cys Ala Leu Arg Tyr Cys Cys Ser Ser Ala Glu 
65                  70                  75                  80  


Ala Arg Leu Asp Gln Gly Gly Cys Asp Asn Asp Arg Gln Gln Gly Ala 
                85                  90                  95      


Gly Glu Pro Gly Arg Ala Asp Lys Asp Gly Pro Asp Gly Ser Ala Val 
            100                 105                 110         


Pro Ile Tyr Val Pro Phe Leu Ile Val Gly Ser Val Phe Val Ala Phe 
        115                 120                 125             


Ile Ile Leu Gly Ser Leu Val Ala Ala Cys Cys Cys Arg Cys Leu Arg 
    130                 135                 140                 


Pro Lys Gln Asp Pro Gln Gln Ser Arg Ala Pro Gly Gly Asn Arg Leu 
145                 150                 155                 160 


Met Glu Thr Ile Pro Met Ile Pro Ser Ala Ser Thr Ser Arg Gly Ser 
                165                 170                 175     


Ser Ser Arg Gln Ser Ser Thr Ala Ala Ser Ser Ser Ser Ser Ala Asn 
            180                 185                 190         


Ser Gly Ala Arg Ala Pro Pro Thr Arg Ser Gln Thr Asn Cys Cys Leu 
        195                 200                 205             


Pro Glu Gly Thr Met Asn Asn Val Tyr Val Asn Met Pro Thr Asn Phe 
    210                 215                 220                 


Ser Val Leu Asn Cys Gln Gln Ala Thr Gln Ile Val Pro His Gln Gly 
225                 230                 235                 240 


Gln Tyr Leu His Pro Pro Tyr Val Gly Tyr Thr Val Gln His Asp Ser 
                245                 250                 255     


Val Pro Met Thr Ala Val Pro Pro Phe Met Asp Gly Leu Gln Pro Gly 
            260                 265                 270         


Tyr Arg Gln Ile Gln Ser Pro Phe Pro His Thr Asn Ser Glu Gln Lys 
        275                 280                 285             


Met Tyr Pro Ala Val Thr Val 
    290                 295 


<210>  2887
<211>  207
<212>  PRT
<213>  homo sapiens

<400>  2887

Met Ser Cys Thr Ile Glu Lys Ile Leu Thr Asp Ala Lys Thr Leu Leu 
1               5                   10                  15      


Glu Arg Leu Arg Glu His Asp Ala Ala Ala Glu Ser Leu Val Asp Gln 
            20                  25                  30          


Ser Ala Ala Leu His Arg Arg Val Ala Ala Met Arg Glu Ala Gly Thr 
        35                  40                  45              


Ala Leu Pro Asp Gln Tyr Gln Glu Asp Ala Ser Asp Met Lys Asp Met 
    50                  55                  60                  


Ser Lys Tyr Lys Pro His Ile Leu Leu Ser Gln Glu Asn Thr Gln Ile 
65                  70                  75                  80  


Arg Asp Leu Gln Gln Glu Asn Arg Glu Leu Trp Ile Ser Leu Glu Glu 
                85                  90                  95      


His Gln Asp Ala Leu Glu Leu Ile Met Ser Lys Tyr Arg Lys Gln Met 
            100                 105                 110         


Leu Gln Leu Met Val Ala Lys Lys Ala Val Asp Ala Glu Pro Val Leu 
        115                 120                 125             


Lys Ala His Gln Ser His Ser Ala Glu Ile Glu Ser Gln Ile Asp Arg 
    130                 135                 140                 


Ile Cys Glu Met Gly Glu Val Met Arg Lys Ala Val Gln Val Asp Asp 
145                 150                 155                 160 


Asp Gln Phe Cys Lys Ile Gln Glu Lys Leu Ala Gln Leu Glu Leu Glu 
                165                 170                 175     


Asn Lys Glu Leu Arg Glu Leu Leu Ser Ile Ser Ser Glu Ser Leu Gln 
            180                 185                 190         


Ala Arg Lys Glu Asn Ser Met Asp Thr Ala Ser Gln Ala Ile Lys 
        195                 200                 205         


<210>  2888
<211>  377
<212>  PRT
<213>  homo sapiens

<400>  2888

Met Cys Glu Glu Glu Asp Ser Thr Ala Leu Val Cys Asp Asn Gly Ser 
1               5                   10                  15      


Gly Leu Cys Lys Ala Gly Phe Ala Gly Asp Asp Ala Pro Arg Ala Val 
            20                  25                  30          


Phe Pro Ser Ile Val Gly Arg Pro Arg His Gln Gly Val Met Val Gly 
        35                  40                  45              


Met Gly Gln Lys Asp Ser Tyr Val Gly Asp Glu Ala Gln Ser Lys Arg 
    50                  55                  60                  


Gly Ile Leu Thr Leu Lys Tyr Pro Ile Glu His Gly Ile Ile Thr Asn 
65                  70                  75                  80  


Trp Asp Asp Met Glu Lys Ile Trp His His Ser Phe Tyr Asn Glu Leu 
                85                  90                  95      


Arg Val Ala Pro Glu Glu His Pro Thr Leu Leu Thr Glu Ala Pro Leu 
            100                 105                 110         


Asn Pro Lys Ala Asn Arg Glu Lys Met Thr Gln Ile Met Phe Glu Thr 
        115                 120                 125             


Phe Asn Val Pro Ala Met Tyr Val Ala Ile Gln Ala Val Leu Ser Leu 
    130                 135                 140                 


Tyr Ala Ser Gly Arg Thr Thr Gly Ile Val Leu Asp Ser Gly Asp Gly 
145                 150                 155                 160 


Val Thr His Asn Val Pro Ile Tyr Glu Gly Tyr Ala Leu Pro His Ala 
                165                 170                 175     


Ile Met Arg Leu Asp Leu Ala Gly Arg Asp Leu Thr Asp Tyr Leu Met 
            180                 185                 190         


Lys Ile Leu Thr Glu Arg Gly Tyr Ser Phe Val Thr Thr Ala Glu Arg 
        195                 200                 205             


Glu Ile Val Arg Asp Ile Lys Glu Lys Leu Cys Tyr Val Ala Leu Asp 
    210                 215                 220                 


Phe Glu Asn Glu Met Ala Thr Ala Ala Ser Ser Ser Ser Leu Glu Lys 
225                 230                 235                 240 


Ser Tyr Glu Leu Pro Asp Gly Gln Val Ile Thr Ile Gly Asn Glu Arg 
                245                 250                 255     


Phe Arg Cys Pro Glu Thr Leu Phe Gln Pro Ser Phe Ile Gly Met Glu 
            260                 265                 270         


Ser Ala Gly Ile His Glu Thr Thr Tyr Asn Ser Ile Met Lys Cys Asp 
        275                 280                 285             


Ile Asp Ile Arg Lys Asp Leu Tyr Ala Asn Asn Val Leu Ser Gly Gly 
    290                 295                 300                 


Thr Thr Met Tyr Pro Gly Ile Ala Asp Arg Met Gln Lys Glu Ile Thr 
305                 310                 315                 320 


Ala Leu Ala Pro Ser Thr Met Lys Ile Lys Ile Ile Ala Pro Pro Glu 
                325                 330                 335     


Arg Lys Tyr Ser Val Trp Ile Gly Gly Ser Ile Leu Ala Ser Leu Ser 
            340                 345                 350         


Thr Phe Gln Gln Met Trp Ile Ser Lys Gln Glu Tyr Asp Glu Ala Gly 
        355                 360                 365             


Pro Ser Ile Val His Arg Lys Cys Phe 
    370                 375         


<210>  2889
<211>  484
<212>  PRT
<213>  homo sapiens

<400>  2889

Met Glu Arg Arg Met Lys Ala Gly Tyr Leu Asp Gln Gln Val Pro Tyr 
1               5                   10                  15      


Thr Phe Ser Ser Lys Ser Pro Gly Asn Gly Ser Leu Arg Glu Ala Leu 
            20                  25                  30          


Ile Gly Pro Leu Gly Lys Leu Met Asp Pro Gly Ser Leu Pro Pro Leu 
        35                  40                  45              


Asp Ser Glu Asp Leu Phe Gln Asp Leu Ser His Phe Gln Glu Thr Trp 
    50                  55                  60                  


Leu Ala Glu Ala Gln Val Pro Asp Ser Asp Glu Gln Phe Val Pro Asp 
65                  70                  75                  80  


Phe His Ser Glu Asn Leu Ala Phe His Ser Pro Thr Thr Arg Ile Lys 
                85                  90                  95      


Lys Glu Pro Gln Ser Pro Arg Thr Asp Pro Ala Leu Ser Cys Ser Arg 
            100                 105                 110         


Lys Pro Pro Leu Pro Tyr His His Gly Glu Gln Cys Leu Tyr Ser Ser 
        115                 120                 125             


Ala Tyr Asp Pro Pro Arg Gln Ile Ala Ile Lys Ser Pro Ala Pro Gly 
    130                 135                 140                 


Ala Leu Gly Gln Ser Pro Leu Gln Pro Phe Pro Arg Ala Glu Gln Arg 
145                 150                 155                 160 


Asn Phe Leu Arg Ser Ser Gly Thr Ser Gln Pro His Pro Gly His Gly 
                165                 170                 175     


Tyr Leu Gly Glu His Ser Ser Val Phe Gln Gln Pro Leu Asp Ile Cys 
            180                 185                 190         


His Ser Phe Thr Ser Gln Gly Gly Gly Arg Glu Pro Leu Pro Ala Pro 
        195                 200                 205             


Tyr Gln His Gln Leu Ser Glu Pro Cys Pro Pro Tyr Pro Gln Gln Ser 
    210                 215                 220                 


Phe Lys Gln Glu Tyr His Asp Pro Leu Tyr Glu Gln Ala Gly Gln Pro 
225                 230                 235                 240 


Ala Val Asp Gln Gly Gly Val Asn Gly His Arg Tyr Pro Gly Ala Gly 
                245                 250                 255     


Val Val Ile Lys Gln Glu Gln Thr Asp Phe Ala Tyr Asp Ser Asp Val 
            260                 265                 270         


Thr Gly Cys Ala Ser Met Tyr Leu His Thr Glu Gly Phe Ser Gly Pro 
        275                 280                 285             


Ser Pro Gly Asp Gly Ala Met Gly Tyr Gly Tyr Glu Lys Pro Leu Arg 
    290                 295                 300                 


Pro Phe Pro Asp Asp Val Cys Val Val Pro Glu Lys Phe Glu Gly Asp 
305                 310                 315                 320 


Ile Lys Gln Glu Gly Val Gly Ala Phe Arg Glu Gly Pro Pro Tyr Gln 
                325                 330                 335     


Arg Arg Gly Ala Leu Gln Leu Trp Gln Phe Leu Val Ala Leu Leu Asp 
            340                 345                 350         


Asp Pro Thr Asn Ala His Phe Ile Ala Trp Thr Gly Arg Gly Met Glu 
        355                 360                 365             


Phe Lys Leu Ile Glu Pro Glu Glu Val Ala Arg Leu Trp Gly Ile Gln 
    370                 375                 380                 


Lys Asn Arg Pro Ala Met Asn Tyr Asp Lys Leu Ser Arg Ser Leu Arg 
385                 390                 395                 400 


Tyr Tyr Tyr Glu Lys Gly Ile Met Gln Lys Val Ala Gly Glu Arg Tyr 
                405                 410                 415     


Val Tyr Lys Phe Val Cys Glu Pro Glu Ala Leu Phe Ser Leu Ala Phe 
            420                 425                 430         


Pro Asp Asn Gln Arg Pro Ala Leu Lys Ala Glu Phe Asp Arg Pro Val 
        435                 440                 445             


Ser Glu Glu Asp Thr Val Pro Leu Ser His Leu Asp Glu Ser Pro Ala 
    450                 455                 460                 


Tyr Leu Pro Glu Leu Ala Gly Pro Ala Gln Pro Phe Gly Pro Lys Gly 
465                 470                 475                 480 


Gly Tyr Ser Tyr 
                


<210>  2890
<211>  208
<212>  PRT
<213>  homo sapiens

<400>  2890

Met Ser Ala Gly Gly Asp Phe Gly Asn Pro Leu Arg Lys Phe Lys Leu 
1               5                   10                  15      


Val Phe Leu Gly Glu Gln Ser Val Gly Lys Thr Ser Leu Ile Thr Arg 
            20                  25                  30          


Phe Met Tyr Asp Ser Phe Asp Asn Thr Tyr Gln Ala Thr Ile Gly Ile 
        35                  40                  45              


Asp Phe Leu Ser Lys Thr Met Tyr Leu Glu Asp Arg Thr Val Arg Leu 
    50                  55                  60                  


Gln Leu Trp Asp Thr Ala Gly Gln Glu Arg Phe Arg Ser Leu Ile Pro 
65                  70                  75                  80  


Ser Tyr Ile Arg Asp Ser Thr Val Ala Val Val Val Tyr Asp Ile Thr 
                85                  90                  95      


Asn Leu Asn Ser Phe Gln Gln Thr Ser Lys Trp Ile Asp Asp Val Arg 
            100                 105                 110         


Thr Glu Arg Gly Ser Asp Val Ile Ile Met Leu Val Gly Asn Lys Thr 
        115                 120                 125             


Asp Leu Ala Asp Lys Arg Gln Ile Thr Ile Glu Glu Gly Glu Gln Arg 
    130                 135                 140                 


Ala Lys Glu Leu Ser Val Met Phe Ile Glu Thr Ser Ala Lys Thr Gly 
145                 150                 155                 160 


Tyr Asn Val Lys Gln Leu Phe Arg Arg Val Ala Ser Ala Leu Pro Gly 
                165                 170                 175     


Met Glu Asn Val Gln Glu Lys Ser Lys Glu Gly Met Ile Asp Ile Lys 
            180                 185                 190         


Leu Asp Lys Pro Gln Glu Pro Pro Ala Ser Glu Gly Gly Cys Ser Cys 
        195                 200                 205             


<210>  2891
<211>  99
<212>  PRT
<213>  homo sapiens

<400>  2891

Met Ala Glu Gly Asn Thr Leu Ile Ser Val Asp Tyr Glu Ile Phe Gly 
1               5                   10                  15      


Lys Val Gln Gly Val Phe Phe Arg Lys His Thr Gln Ala Glu Gly Lys 
            20                  25                  30          


Lys Leu Gly Leu Val Gly Trp Val Gln Asn Thr Asp Arg Gly Thr Val 
        35                  40                  45              


Gln Gly Gln Leu Gln Gly Pro Ile Ser Lys Val Arg His Met Gln Glu 
    50                  55                  60                  


Trp Leu Glu Thr Arg Gly Ser Pro Lys Ser His Ile Asp Lys Ala Asn 
65                  70                  75                  80  


Phe Asn Asn Glu Lys Val Ile Leu Lys Leu Asp Tyr Ser Asp Phe Gln 
                85                  90                  95      


Ile Val Lys 
            


<210>  2892
<211>  578
<212>  PRT
<213>  homo sapiens

<400>  2892

Met Ala Val Ser Trp Arg Ser Trp Leu Ala Asn Glu Gly Val Lys His 
1               5                   10                  15      


Leu Cys Leu Phe Ile Trp Leu Ser Met Asn Val Leu Leu Phe Trp Lys 
            20                  25                  30          


Thr Phe Leu Leu Tyr Asn Gln Gly Pro Glu Tyr His Tyr Leu His Gln 
        35                  40                  45              


Met Leu Gly Leu Gly Leu Cys Leu Ser Arg Ala Ser Ala Ser Val Leu 
    50                  55                  60                  


Asn Leu Asn Cys Ser Leu Ile Leu Leu Pro Met Cys Arg Thr Leu Leu 
65                  70                  75                  80  


Ala Tyr Leu Arg Gly Ser Gln Lys Val Pro Ser Arg Arg Thr Arg Arg 
                85                  90                  95      


Leu Leu Asp Lys Ser Arg Thr Phe His Ile Thr Cys Gly Val Thr Ile 
            100                 105                 110         


Cys Ile Phe Ser Gly Val His Val Ala Ala His Leu Val Asn Ala Leu 
        115                 120                 125             


Asn Phe Ser Val Asn Tyr Ser Glu Asp Phe Val Glu Leu Asn Ala Ala 
    130                 135                 140                 


Arg Tyr Arg Asp Glu Asp Pro Arg Lys Leu Leu Phe Thr Thr Val Pro 
145                 150                 155                 160 


Gly Leu Thr Gly Val Cys Met Val Val Val Leu Phe Leu Met Ile Thr 
                165                 170                 175     


Ala Ser Thr Tyr Ala Ile Arg Val Ser Asn Tyr Asp Ile Phe Trp Tyr 
            180                 185                 190         


Thr His Asn Leu Phe Phe Val Phe Tyr Met Leu Leu Thr Leu His Val 
        195                 200                 205             


Ser Gly Gly Leu Leu Lys Tyr Gln Thr Asn Leu Asp Thr His Pro Pro 
    210                 215                 220                 


Gly Cys Ile Ser Leu Asn Arg Thr Ser Ser Gln Asn Ile Ser Leu Pro 
225                 230                 235                 240 


Glu Tyr Phe Ser Glu His Phe His Glu Pro Phe Pro Glu Gly Phe Ser 
                245                 250                 255     


Lys Pro Ala Glu Phe Thr Gln His Lys Phe Val Lys Ile Cys Met Glu 
            260                 265                 270         


Glu Pro Arg Phe Gln Ala Asn Phe Pro Gln Thr Trp Leu Trp Ile Ser 
        275                 280                 285             


Gly Pro Leu Cys Leu Tyr Cys Ala Glu Arg Leu Tyr Arg Tyr Ile Arg 
    290                 295                 300                 


Ser Asn Lys Pro Val Thr Ile Ile Ser Val Ile Ser His Pro Ser Asp 
305                 310                 315                 320 


Val Met Glu Ile Arg Met Val Lys Glu Asn Phe Lys Ala Arg Pro Gly 
                325                 330                 335     


Gln Tyr Ile Thr Leu His Cys Pro Ser Val Ser Ala Leu Glu Asn His 
            340                 345                 350         


Pro Phe Thr Leu Thr Met Cys Pro Thr Glu Thr Lys Ala Thr Phe Gly 
        355                 360                 365             


Val His Leu Lys Ile Val Gly Asp Trp Thr Glu Arg Phe Arg Asp Leu 
    370                 375                 380                 


Leu Leu Pro Pro Ser Ser Gln Asp Ser Glu Ile Leu Pro Phe Ile Gln 
385                 390                 395                 400 


Ser Arg Asn Tyr Pro Lys Leu Tyr Ile Asp Gly Pro Phe Gly Ser Pro 
                405                 410                 415     


Phe Glu Glu Ser Leu Asn Tyr Glu Val Ser Leu Cys Val Ala Gly Gly 
            420                 425                 430         


Ile Gly Val Thr Pro Phe Ala Ser Ile Leu Asn Thr Leu Leu Asp Asp 
        435                 440                 445             


Trp Lys Pro Tyr Lys Leu Arg Arg Leu Tyr Phe Ile Trp Val Cys Arg 
    450                 455                 460                 


Asp Ile Gln Ser Phe Arg Trp Phe Ala Asp Leu Leu Cys Met Leu His 
465                 470                 475                 480 


Asn Lys Phe Trp Gln Glu Asn Arg Pro Asp Tyr Val Asn Ile Gln Leu 
                485                 490                 495     


Tyr Leu Ser Gln Thr Asp Gly Ile Gln Lys Ile Ile Gly Glu Lys Tyr 
            500                 505                 510         


His Ala Leu Asn Ser Arg Leu Phe Ile Gly Arg Pro Arg Trp Lys Leu 
        515                 520                 525             


Leu Phe Asp Glu Ile Ala Lys Tyr Asn Arg Gly Lys Thr Val Gly Val 
    530                 535                 540                 


Phe Cys Cys Gly Pro Asn Ser Leu Ser Lys Thr Leu His Lys Leu Ser 
545                 550                 555                 560 


Asn Gln Asn Asn Ser Tyr Gly Thr Arg Phe Glu Tyr Asn Lys Glu Ser 
                565                 570                 575     


Phe Ser 
        


<210>  2893
<211>  538
<212>  PRT
<213>  homo sapiens

<400>  2893

Met Ala Val Ser Trp Arg Ser Trp Leu Ala Asn Glu Gly Val Lys His 
1               5                   10                  15      


Leu Cys Leu Phe Ile Trp Leu Ser Met Asn Val Leu Leu Phe Trp Lys 
            20                  25                  30          


Thr Phe Leu Leu Tyr Asn Gln Gly Pro Glu Tyr His Tyr Leu His Gln 
        35                  40                  45              


Met Leu Gly Leu Gly Leu Cys Leu Ser Arg Ala Ser Ala Ser Val Leu 
    50                  55                  60                  


Asn Leu Asn Cys Ser Leu Ile Leu Leu Pro Met Cys Arg Thr Leu Leu 
65                  70                  75                  80  


Ala Tyr Leu Arg Gly Ser Gln Lys Val Pro Ser Arg Arg Thr Arg Arg 
                85                  90                  95      


Leu Leu Asp Lys Ser Arg Thr Phe His Ile Thr Cys Gly Val Thr Ile 
            100                 105                 110         


Cys Ile Phe Ser Gly Val His Val Ala Ala His Leu Val Asn Ala Leu 
        115                 120                 125             


Asn Phe Ser Val Asn Tyr Ser Glu Asp Phe Val Glu Leu Asn Ala Ala 
    130                 135                 140                 


Arg Tyr Arg Asp Glu Asp Pro Arg Lys Leu Leu Phe Thr Thr Val Pro 
145                 150                 155                 160 


Gly Leu Thr Gly Val Cys Met Val Val Val Leu Phe Leu Met Ile Thr 
                165                 170                 175     


Ala Ser Thr Tyr Ala Ile Arg Val Ser Asn Tyr Asp Ile Phe Trp Tyr 
            180                 185                 190         


Thr His Asn Leu Phe Phe Val Phe Tyr Met Leu Leu Thr Leu His Val 
        195                 200                 205             


Ser Gly Gly Leu Leu Lys Tyr Gln Thr Asn Leu Asp Thr His Pro Pro 
    210                 215                 220                 


Gly Cys Ile Ser Leu Asn Arg Thr Ser Ser Gln Asn Ile Ser Leu Pro 
225                 230                 235                 240 


Glu Tyr Phe Ser Glu His Phe His Glu Pro Phe Pro Glu Gly Phe Ser 
                245                 250                 255     


Lys Pro Ala Glu Phe Thr Gln His Lys Phe Val Lys Ile Cys Met Glu 
            260                 265                 270         


Glu Pro Arg Phe Gln Ala Asn Phe Pro Gln Thr Trp Leu Trp Ile Ser 
        275                 280                 285             


Gly Pro Leu Cys Leu Tyr Cys Ala Glu Arg Leu Tyr Arg Tyr Ile Arg 
    290                 295                 300                 


Ser Asn Lys Pro Val Thr Ile Ile Ser Val Ile Ser His Pro Ser Asp 
305                 310                 315                 320 


Val Met Glu Ile Arg Met Val Lys Glu Asn Phe Lys Ala Arg Pro Gly 
                325                 330                 335     


Gln Tyr Ile Thr Leu His Cys Pro Ser Val Ser Ala Leu Glu Asn His 
            340                 345                 350         


Pro Phe Thr Leu Thr Met Cys Pro Thr Glu Thr Lys Ala Thr Phe Gly 
        355                 360                 365             


Val His Leu Lys Ile Val Gly Asp Trp Thr Glu Arg Phe Arg Asp Leu 
    370                 375                 380                 


Leu Leu Pro Pro Ser Ser Gln Asp Ser Glu Ile Leu Pro Phe Ile Gln 
385                 390                 395                 400 


Ser Arg Asn Tyr Pro Lys Asp Asp Trp Lys Pro Tyr Lys Leu Arg Arg 
                405                 410                 415     


Leu Tyr Phe Ile Trp Val Cys Arg Asp Ile Gln Ser Phe Arg Trp Phe 
            420                 425                 430         


Ala Asp Leu Leu Cys Met Leu His Asn Lys Phe Trp Gln Glu Asn Arg 
        435                 440                 445             


Pro Asp Tyr Val Asn Ile Gln Leu Tyr Leu Ser Gln Thr Asp Gly Ile 
    450                 455                 460                 


Gln Lys Ile Ile Gly Glu Lys Tyr His Ala Leu Asn Ser Arg Leu Phe 
465                 470                 475                 480 


Ile Gly Arg Pro Arg Trp Lys Leu Leu Phe Asp Glu Ile Ala Lys Tyr 
                485                 490                 495     


Asn Arg Gly Lys Thr Val Gly Val Phe Cys Cys Gly Pro Asn Ser Leu 
            500                 505                 510         


Ser Lys Thr Leu His Lys Leu Ser Asn Gln Asn Asn Ser Tyr Gly Thr 
        515                 520                 525             


Arg Phe Glu Tyr Asn Lys Glu Ser Phe Ser 
    530                 535             


<210>  2894
<211>  847
<212>  PRT
<213>  homo sapiens

<400>  2894

Met Ala Lys Pro Leu Thr Asp Gln Glu Lys Arg Arg Gln Ile Ser Ile 
1               5                   10                  15      


Arg Gly Ile Val Gly Val Glu Asn Val Ala Glu Leu Lys Lys Ser Phe 
            20                  25                  30          


Asn Arg His Leu His Phe Thr Leu Val Lys Asp Arg Asn Val Ala Thr 
        35                  40                  45              


Thr Arg Asp Tyr Tyr Phe Ala Leu Ala His Thr Val Arg Asp His Leu 
    50                  55                  60                  


Val Gly Arg Trp Ile Arg Thr Gln Gln His Tyr Tyr Asp Lys Cys Pro 
65                  70                  75                  80  


Lys Arg Val Tyr Tyr Leu Ser Leu Glu Phe Tyr Met Gly Arg Thr Leu 
                85                  90                  95      


Gln Asn Thr Met Ile Asn Leu Gly Leu Gln Asn Ala Cys Asp Glu Ala 
            100                 105                 110         


Ile Tyr Gln Leu Gly Leu Asp Ile Glu Glu Leu Glu Glu Ile Glu Glu 
        115                 120                 125             


Asp Ala Gly Leu Gly Asn Gly Gly Leu Gly Arg Leu Ala Ala Cys Phe 
    130                 135                 140                 


Leu Asp Ser Met Ala Thr Leu Gly Leu Ala Ala Tyr Gly Tyr Gly Ile 
145                 150                 155                 160 


Arg Tyr Glu Tyr Gly Ile Phe Asn Gln Lys Ile Arg Asp Gly Trp Gln 
                165                 170                 175     


Val Glu Glu Ala Asp Asp Trp Leu Arg Tyr Gly Asn Pro Trp Glu Lys 
            180                 185                 190         


Ser Arg Pro Glu Phe Met Leu Pro Val His Phe Tyr Gly Lys Val Glu 
        195                 200                 205             


His Thr Asn Thr Gly Thr Lys Trp Ile Asp Thr Gln Val Val Leu Ala 
    210                 215                 220                 


Leu Pro Tyr Asp Thr Pro Val Pro Gly Tyr Met Asn Asn Thr Val Asn 
225                 230                 235                 240 


Thr Met Arg Leu Trp Ser Ala Arg Ala Pro Asn Asp Phe Asn Leu Arg 
                245                 250                 255     


Asp Phe Asn Val Gly Asp Tyr Ile Gln Ala Val Leu Asp Arg Asn Leu 
            260                 265                 270         


Ala Glu Asn Ile Ser Arg Val Leu Tyr Pro Asn Asp Asn Phe Phe Glu 
        275                 280                 285             


Gly Lys Glu Leu Arg Leu Lys Gln Glu Tyr Phe Val Val Ala Ala Thr 
    290                 295                 300                 


Leu Gln Asp Ile Ile Arg Arg Phe Lys Ala Ser Lys Phe Gly Ser Thr 
305                 310                 315                 320 


Arg Gly Ala Gly Thr Val Phe Asp Ala Phe Pro Asp Gln Val Ala Ile 
                325                 330                 335     


Gln Leu Asn Asp Thr His Pro Ala Leu Ala Ile Pro Glu Leu Met Arg 
            340                 345                 350         


Ile Phe Val Asp Ile Glu Lys Leu Pro Trp Ser Lys Ala Trp Glu Leu 
        355                 360                 365             


Thr Gln Lys Thr Phe Ala Tyr Thr Asn His Thr Val Leu Pro Glu Ala 
    370                 375                 380                 


Leu Glu Arg Trp Pro Val Asp Leu Val Glu Lys Leu Leu Pro Arg His 
385                 390                 395                 400 


Leu Glu Ile Ile Tyr Glu Ile Asn Gln Lys His Leu Asp Arg Ile Val 
                405                 410                 415     


Ala Leu Phe Pro Lys Asp Val Asp Arg Leu Arg Arg Met Ser Leu Ile 
            420                 425                 430         


Glu Glu Glu Gly Ser Lys Arg Ile Asn Met Ala His Leu Cys Ile Val 
        435                 440                 445             


Gly Ser His Ala Val Asn Gly Val Ala Lys Ile His Ser Asp Ile Val 
    450                 455                 460                 


Lys Thr Lys Val Phe Lys Asp Phe Ser Glu Leu Glu Pro Asp Lys Phe 
465                 470                 475                 480 


Gln Asn Lys Thr Asn Gly Ile Thr Pro Arg Arg Trp Leu Leu Leu Cys 
                485                 490                 495     


Asn Pro Gly Leu Ala Glu Leu Ile Ala Glu Lys Ile Gly Glu Asp Tyr 
            500                 505                 510         


Val Lys Asp Leu Ser Gln Leu Thr Lys Leu His Ser Phe Leu Gly Asp 
        515                 520                 525             


Asp Val Phe Leu Arg Glu Leu Ala Lys Val Lys Gln Glu Asn Lys Leu 
    530                 535                 540                 


Lys Phe Ser Gln Phe Leu Glu Thr Glu Tyr Lys Val Lys Ile Asn Pro 
545                 550                 555                 560 


Ser Ser Met Phe Asp Val Gln Val Lys Arg Ile His Glu Tyr Lys Arg 
                565                 570                 575     


Gln Leu Leu Asn Cys Leu His Val Ile Thr Met Tyr Asn Arg Ile Lys 
            580                 585                 590         


Lys Asp Pro Lys Lys Leu Phe Val Pro Arg Thr Val Ile Ile Gly Gly 
        595                 600                 605             


Lys Ala Ala Pro Gly Tyr His Met Ala Lys Met Ile Ile Lys Leu Ile 
    610                 615                 620                 


Thr Ser Val Ala Asp Val Val Asn Asn Asp Pro Met Val Gly Ser Lys 
625                 630                 635                 640 


Leu Lys Val Ile Phe Leu Glu Asn Tyr Arg Val Ser Leu Ala Glu Lys 
                645                 650                 655     


Val Ile Pro Ala Thr Asp Leu Ser Glu Gln Ile Ser Thr Ala Gly Thr 
            660                 665                 670         


Glu Ala Ser Gly Thr Gly Asn Met Lys Phe Met Leu Asn Gly Ala Leu 
        675                 680                 685             


Thr Ile Gly Thr Met Asp Gly Ala Asn Val Glu Met Ala Glu Glu Ala 
    690                 695                 700                 


Gly Glu Glu Asn Leu Phe Ile Phe Gly Met Arg Ile Asp Asp Val Ala 
705                 710                 715                 720 


Ala Leu Asp Lys Lys Gly Tyr Glu Ala Lys Glu Tyr Tyr Glu Ala Leu 
                725                 730                 735     


Pro Glu Leu Lys Leu Val Ile Asp Gln Ile Asp Asn Gly Phe Phe Ser 
            740                 745                 750         


Pro Lys Gln Pro Asp Leu Phe Lys Asp Ile Ile Asn Met Leu Phe Tyr 
        755                 760                 765             


His Asp Arg Phe Lys Val Phe Ala Asp Tyr Glu Ala Tyr Val Lys Cys 
    770                 775                 780                 


Gln Asp Lys Val Ser Gln Leu Tyr Met Asn Pro Lys Ala Trp Asn Thr 
785                 790                 795                 800 


Met Val Leu Lys Asn Ile Ala Ala Ser Gly Lys Phe Ser Ser Asp Arg 
                805                 810                 815     


Thr Ile Lys Glu Tyr Ala Gln Asn Ile Trp Asn Val Glu Pro Ser Asp 
            820                 825                 830         


Leu Lys Ile Ser Leu Ser Asn Glu Ser Asn Lys Val Asn Gly Asn 
        835                 840                 845         


<210>  2895
<211>  813
<212>  PRT
<213>  homo sapiens

<400>  2895

Met Ala Lys Pro Leu Thr Asp Gln Glu Lys Arg Arg Gln Ile Ser Ile 
1               5                   10                  15      


Arg Gly Ile Val Gly Val Glu Asn Val Ala Glu Leu Lys Lys Ser Phe 
            20                  25                  30          


Asn Arg His Leu His Phe Thr Leu Val Lys Asp Arg Asn Val Ala Thr 
        35                  40                  45              


Thr Arg Asp Tyr Tyr Phe Ala Leu Ala His Thr Val Arg Asp His Leu 
    50                  55                  60                  


Val Gly Arg Trp Ile Arg Thr Gln Gln His Tyr Tyr Asp Lys Cys Pro 
65                  70                  75                  80  


Lys Leu Gly Leu Asp Ile Glu Glu Leu Glu Glu Ile Glu Glu Asp Ala 
                85                  90                  95      


Gly Leu Gly Asn Gly Gly Leu Gly Arg Leu Ala Ala Cys Phe Leu Asp 
            100                 105                 110         


Ser Met Ala Thr Leu Gly Leu Ala Ala Tyr Gly Tyr Gly Ile Arg Tyr 
        115                 120                 125             


Glu Tyr Gly Ile Phe Asn Gln Lys Ile Arg Asp Gly Trp Gln Val Glu 
    130                 135                 140                 


Glu Ala Asp Asp Trp Leu Arg Tyr Gly Asn Pro Trp Glu Lys Ser Arg 
145                 150                 155                 160 


Pro Glu Phe Met Leu Pro Val His Phe Tyr Gly Lys Val Glu His Thr 
                165                 170                 175     


Asn Thr Gly Thr Lys Trp Ile Asp Thr Gln Val Val Leu Ala Leu Pro 
            180                 185                 190         


Tyr Asp Thr Pro Val Pro Gly Tyr Met Asn Asn Thr Val Asn Thr Met 
        195                 200                 205             


Arg Leu Trp Ser Ala Arg Ala Pro Asn Asp Phe Asn Leu Arg Asp Phe 
    210                 215                 220                 


Asn Val Gly Asp Tyr Ile Gln Ala Val Leu Asp Arg Asn Leu Ala Glu 
225                 230                 235                 240 


Asn Ile Ser Arg Val Leu Tyr Pro Asn Asp Asn Phe Phe Glu Gly Lys 
                245                 250                 255     


Glu Leu Arg Leu Lys Gln Glu Tyr Phe Val Val Ala Ala Thr Leu Gln 
            260                 265                 270         


Asp Ile Ile Arg Arg Phe Lys Ala Ser Lys Phe Gly Ser Thr Arg Gly 
        275                 280                 285             


Ala Gly Thr Val Phe Asp Ala Phe Pro Asp Gln Val Ala Ile Gln Leu 
    290                 295                 300                 


Asn Asp Thr His Pro Ala Leu Ala Ile Pro Glu Leu Met Arg Ile Phe 
305                 310                 315                 320 


Val Asp Ile Glu Lys Leu Pro Trp Ser Lys Ala Trp Glu Leu Thr Gln 
                325                 330                 335     


Lys Thr Phe Ala Tyr Thr Asn His Thr Val Leu Pro Glu Ala Leu Glu 
            340                 345                 350         


Arg Trp Pro Val Asp Leu Val Glu Lys Leu Leu Pro Arg His Leu Glu 
        355                 360                 365             


Ile Ile Tyr Glu Ile Asn Gln Lys His Leu Asp Arg Ile Val Ala Leu 
    370                 375                 380                 


Phe Pro Lys Asp Val Asp Arg Leu Arg Arg Met Ser Leu Ile Glu Glu 
385                 390                 395                 400 


Glu Gly Ser Lys Arg Ile Asn Met Ala His Leu Cys Ile Val Gly Ser 
                405                 410                 415     


His Ala Val Asn Gly Val Ala Lys Ile His Ser Asp Ile Val Lys Thr 
            420                 425                 430         


Lys Val Phe Lys Asp Phe Ser Glu Leu Glu Pro Asp Lys Phe Gln Asn 
        435                 440                 445             


Lys Thr Asn Gly Ile Thr Pro Arg Arg Trp Leu Leu Leu Cys Asn Pro 
    450                 455                 460                 


Gly Leu Ala Glu Leu Ile Ala Glu Lys Ile Gly Glu Asp Tyr Val Lys 
465                 470                 475                 480 


Asp Leu Ser Gln Leu Thr Lys Leu His Ser Phe Leu Gly Asp Asp Val 
                485                 490                 495     


Phe Leu Arg Glu Leu Ala Lys Val Lys Gln Glu Asn Lys Leu Lys Phe 
            500                 505                 510         


Ser Gln Phe Leu Glu Thr Glu Tyr Lys Val Lys Ile Asn Pro Ser Ser 
        515                 520                 525             


Met Phe Asp Val Gln Val Lys Arg Ile His Glu Tyr Lys Arg Gln Leu 
    530                 535                 540                 


Leu Asn Cys Leu His Val Ile Thr Met Tyr Asn Arg Ile Lys Lys Asp 
545                 550                 555                 560 


Pro Lys Lys Leu Phe Val Pro Arg Thr Val Ile Ile Gly Gly Lys Ala 
                565                 570                 575     


Ala Pro Gly Tyr His Met Ala Lys Met Ile Ile Lys Leu Ile Thr Ser 
            580                 585                 590         


Val Ala Asp Val Val Asn Asn Asp Pro Met Val Gly Ser Lys Leu Lys 
        595                 600                 605             


Val Ile Phe Leu Glu Asn Tyr Arg Val Ser Leu Ala Glu Lys Val Ile 
    610                 615                 620                 


Pro Ala Thr Asp Leu Ser Glu Gln Ile Ser Thr Ala Gly Thr Glu Ala 
625                 630                 635                 640 


Ser Gly Thr Gly Asn Met Lys Phe Met Leu Asn Gly Ala Leu Thr Ile 
                645                 650                 655     


Gly Thr Met Asp Gly Ala Asn Val Glu Met Ala Glu Glu Ala Gly Glu 
            660                 665                 670         


Glu Asn Leu Phe Ile Phe Gly Met Arg Ile Asp Asp Val Ala Ala Leu 
        675                 680                 685             


Asp Lys Lys Gly Tyr Glu Ala Lys Glu Tyr Tyr Glu Ala Leu Pro Glu 
    690                 695                 700                 


Leu Lys Leu Val Ile Asp Gln Ile Asp Asn Gly Phe Phe Ser Pro Lys 
705                 710                 715                 720 


Gln Pro Asp Leu Phe Lys Asp Ile Ile Asn Met Leu Phe Tyr His Asp 
                725                 730                 735     


Arg Phe Lys Val Phe Ala Asp Tyr Glu Ala Tyr Val Lys Cys Gln Asp 
            740                 745                 750         


Lys Val Ser Gln Leu Tyr Met Asn Pro Lys Ala Trp Asn Thr Met Val 
        755                 760                 765             


Leu Lys Asn Ile Ala Ala Ser Gly Lys Phe Ser Ser Asp Arg Thr Ile 
    770                 775                 780                 


Lys Glu Tyr Ala Gln Asn Ile Trp Asn Val Glu Pro Ser Asp Leu Lys 
785                 790                 795                 800 


Ile Ser Leu Ser Asn Glu Ser Asn Lys Val Asn Gly Asn 
                805                 810             


<210>  2896
<211>  1205
<212>  PRT
<213>  homo sapiens

<400>  2896

Met Val Leu Leu Ser Leu Trp Leu Ile Ala Ala Ala Leu Val Glu Val 
1               5                   10                  15      


Arg Thr Ser Ala Asp Gly Gln Ala Gly Asn Glu Glu Met Val Gln Ile 
            20                  25                  30          


Asp Leu Pro Ile Lys Arg Tyr Arg Glu Tyr Glu Leu Val Thr Pro Val 
        35                  40                  45              


Ser Thr Asn Leu Glu Gly Arg Tyr Leu Ser His Thr Leu Ser Ala Ser 
    50                  55                  60                  


His Lys Lys Arg Ser Ala Arg Asp Val Ser Ser Asn Pro Glu Gln Leu 
65                  70                  75                  80  


Phe Phe Asn Ile Thr Ala Phe Gly Lys Asp Phe His Leu Arg Leu Lys 
                85                  90                  95      


Pro Asn Thr Gln Leu Val Ala Pro Gly Ala Val Val Glu Trp His Glu 
            100                 105                 110         


Thr Ser Leu Val Pro Gly Asn Ile Thr Asp Pro Ile Asn Asn His Gln 
        115                 120                 125             


Pro Gly Ser Ala Thr Tyr Arg Ile Arg Arg Thr Glu Pro Leu Gln Thr 
    130                 135                 140                 


Asn Cys Ala Tyr Val Gly Asp Ile Val Asp Ile Pro Gly Thr Ser Val 
145                 150                 155                 160 


Ala Ile Ser Asn Cys Asp Gly Leu Ala Gly Met Ile Lys Ser Asp Asn 
                165                 170                 175     


Glu Glu Tyr Phe Ile Glu Pro Leu Glu Arg Gly Lys Gln Met Glu Glu 
            180                 185                 190         


Glu Lys Gly Arg Ile His Val Val Tyr Lys Arg Ser Ala Val Glu Gln 
        195                 200                 205             


Ala Pro Ile Asp Met Ser Lys Asp Phe His Tyr Arg Glu Ser Asp Leu 
    210                 215                 220                 


Glu Gly Leu Asp Asp Leu Gly Thr Val Tyr Gly Asn Ile His Gln Gln 
225                 230                 235                 240 


Leu Asn Glu Thr Met Arg Arg Arg Arg His Ala Gly Glu Asn Asp Tyr 
                245                 250                 255     


Asn Ile Glu Val Leu Leu Gly Val Asp Asp Ser Val Val Arg Phe His 
            260                 265                 270         


Gly Lys Glu His Val Gln Asn Tyr Leu Leu Thr Leu Met Asn Ile Val 
        275                 280                 285             


Asn Glu Ile Tyr His Asp Glu Ser Leu Gly Val His Ile Asn Val Val 
    290                 295                 300                 


Leu Val Arg Met Ile Met Leu Gly Tyr Ala Lys Ser Ile Ser Leu Ile 
305                 310                 315                 320 


Glu Arg Gly Asn Pro Ser Arg Ser Leu Glu Asn Val Cys Arg Trp Ala 
                325                 330                 335     


Ser Gln Gln Gln Arg Ser Asp Leu Asn His Ser Glu His His Asp His 
            340                 345                 350         


Ala Ile Phe Leu Thr Arg Gln Asp Phe Gly Pro Ala Gly Met Gln Gly 
        355                 360                 365             


Tyr Ala Pro Val Thr Gly Met Cys His Pro Val Arg Ser Cys Thr Leu 
    370                 375                 380                 


Asn His Glu Asp Gly Phe Ser Ser Ala Phe Val Val Ala His Glu Thr 
385                 390                 395                 400 


Gly His Val Leu Gly Met Glu His Asp Gly Gln Gly Asn Arg Cys Gly 
                405                 410                 415     


Asp Glu Thr Ala Met Gly Ser Val Met Ala Pro Leu Val Gln Ala Ala 
            420                 425                 430         


Phe His Arg Tyr His Trp Ser Arg Cys Ser Gly Gln Glu Leu Lys Arg 
        435                 440                 445             


Tyr Ile His Ser Tyr Asp Cys Leu Leu Asp Asp Pro Phe Asp His Asp 
    450                 455                 460                 


Trp Pro Lys Leu Pro Glu Leu Pro Gly Ile Asn Tyr Ser Met Asp Glu 
465                 470                 475                 480 


Gln Cys Arg Phe Asp Phe Gly Val Gly Tyr Lys Met Cys Thr Ala Phe 
                485                 490                 495     


Arg Thr Phe Asp Pro Cys Lys Gln Leu Trp Cys Ser His Pro Asp Asn 
            500                 505                 510         


Pro Tyr Phe Cys Lys Thr Lys Lys Gly Pro Pro Leu Asp Gly Thr Glu 
        515                 520                 525             


Cys Ala Ala Gly Lys Trp Cys Tyr Lys Gly His Cys Met Trp Lys Asn 
    530                 535                 540                 


Ala Asn Gln Gln Lys Gln Asp Gly Asn Trp Gly Ser Trp Thr Lys Phe 
545                 550                 555                 560 


Gly Ser Cys Ser Arg Thr Cys Gly Thr Gly Val Arg Phe Arg Thr Arg 
                565                 570                 575     


Gln Cys Asn Asn Pro Met Pro Ile Asn Gly Gly Gln Asp Cys Pro Gly 
            580                 585                 590         


Val Asn Phe Glu Tyr Gln Leu Cys Asn Thr Glu Glu Cys Gln Lys His 
        595                 600                 605             


Phe Glu Asp Phe Arg Ala Gln Gln Cys Gln Gln Arg Asn Ser His Phe 
    610                 615                 620                 


Glu Tyr Gln Asn Thr Lys His His Trp Leu Pro Tyr Glu His Pro Asp 
625                 630                 635                 640 


Pro Lys Lys Arg Cys His Leu Tyr Cys Gln Ser Lys Glu Thr Gly Asp 
                645                 650                 655     


Val Ala Tyr Met Lys Gln Leu Val His Asp Gly Thr His Cys Ser Tyr 
            660                 665                 670         


Lys Asp Pro Tyr Ser Ile Cys Val Arg Gly Glu Cys Val Lys Val Gly 
        675                 680                 685             


Cys Asp Lys Glu Ile Gly Ser Asn Lys Val Glu Asp Lys Cys Gly Val 
    690                 695                 700                 


Cys Gly Gly Asp Asn Ser His Cys Arg Thr Val Lys Gly Thr Phe Thr 
705                 710                 715                 720 


Arg Thr Pro Arg Lys Leu Gly Tyr Leu Lys Met Phe Asp Ile Pro Pro 
                725                 730                 735     


Gly Ala Arg His Val Leu Ile Gln Glu Asp Glu Ala Ser Pro His Ile 
            740                 745                 750         


Leu Ala Ile Lys Asn Gln Ala Thr Gly His Tyr Ile Leu Asn Gly Lys 
        755                 760                 765             


Gly Glu Glu Ala Lys Ser Arg Thr Phe Ile Asp Leu Gly Val Glu Trp 
    770                 775                 780                 


Asp Tyr Asn Ile Glu Asp Asp Ile Glu Ser Leu His Thr Asp Gly Pro 
785                 790                 795                 800 


Leu His Asp Pro Val Ile Val Leu Ile Ile Pro Gln Glu Asn Asp Thr 
                805                 810                 815     


Arg Ser Ser Leu Thr Tyr Lys Tyr Ile Ile His Glu Asp Ser Val Pro 
            820                 825                 830         


Thr Ile Asn Ser Asn Asn Val Ile Gln Glu Glu Leu Asp Thr Phe Glu 
        835                 840                 845             


Trp Ala Leu Lys Ser Trp Ser Gln Cys Ser Lys Pro Cys Gly Gly Gly 
    850                 855                 860                 


Phe Gln Tyr Thr Lys Tyr Gly Cys Arg Arg Lys Ser Asp Asn Lys Met 
865                 870                 875                 880 


Val His Arg Ser Phe Cys Glu Ala Asn Lys Lys Pro Lys Pro Ile Arg 
                885                 890                 895     


Arg Met Cys Asn Ile Gln Glu Cys Thr His Pro Leu Trp Val Ala Glu 
            900                 905                 910         


Glu Trp Glu His Cys Thr Lys Thr Cys Gly Ser Ser Gly Tyr Gln Leu 
        915                 920                 925             


Arg Thr Val Arg Cys Leu Gln Pro Leu Leu Asp Gly Thr Asn Arg Ser 
    930                 935                 940                 


Val His Ser Lys Tyr Cys Met Gly Asp Arg Pro Glu Ser Arg Arg Pro 
945                 950                 955                 960 


Cys Asn Arg Val Pro Cys Pro Ala Gln Trp Lys Thr Gly Pro Trp Ser 
                965                 970                 975     


Glu Cys Ser Val Thr Cys Gly Glu Gly Thr Glu Val Arg Gln Val Leu 
            980                 985                 990         


Cys Arg Ala Gly Asp His Cys Asp  Gly Glu Lys Pro Glu  Ser Val Arg 
        995                 1000                 1005             


Ala Cys  Gln Leu Pro Pro Cys  Asn Asp Glu Pro Cys  Leu Gly Asp 
    1010                 1015                 1020             


Lys Ser  Ile Phe Cys Gln Met  Glu Val Leu Ala Arg  Tyr Cys Ser 
    1025                 1030                 1035             


Ile Pro  Gly Tyr Asn Lys Leu  Cys Cys Glu Ser Cys  Ser Lys Arg 
    1040                 1045                 1050             


Ser Ser  Thr Leu Pro Pro Pro  Tyr Leu Leu Glu Ala  Ala Glu Thr 
    1055                 1060                 1065             


His Asp  Asp Val Ile Ser Asn  Pro Ser Asp Leu Pro  Arg Ser Leu 
    1070                 1075                 1080             


Val Met  Pro Thr Ser Leu Val  Pro Tyr His Ser Glu  Thr Pro Ala 
    1085                 1090                 1095             


Lys Lys  Met Ser Leu Ser Ser  Ile Ser Ser Val Gly  Gly Pro Asn 
    1100                 1105                 1110             


Ala Tyr  Ala Ala Phe Arg Pro  Asn Ser Lys Pro Asp  Gly Ala Asn 
    1115                 1120                 1125             


Leu Arg  Gln Arg Ser Ala Gln  Gln Ala Gly Ser Lys  Thr Val Arg 
    1130                 1135                 1140             


Leu Val  Thr Val Pro Ser Ser  Pro Pro Thr Lys Arg  Val His Leu 
    1145                 1150                 1155             


Ser Ser  Ala Ser Gln Met Ala  Ala Ala Ser Phe Phe  Ala Ala Ser 
    1160                 1165                 1170             


Asp Ser  Ile Gly Ala Ser Ser  Gln Ala Arg Thr Ser  Lys Lys Asp 
    1175                 1180                 1185             


Gly Lys  Ile Ile Asp Asn Arg  Arg Pro Thr Arg Ser  Ser Thr Leu 
    1190                 1195                 1200             


Glu Arg  
    1205 


<210>  2897
<211>  858
<212>  PRT
<213>  homo sapiens

<400>  2897

Met Glu Asn Glu Leu Pro Val Pro His Thr Ser Ser Ser Ala Cys Ala 
1               5                   10                  15      


Thr Ser Ser Thr Ser Gly Ala Ser Ser Ser Ser Gly Cys Asn Asn Ser 
            20                  25                  30          


Ser Ser Gly Gly Ser Gly Arg Pro Thr Gly Pro Gln Ile Ser Val Tyr 
        35                  40                  45              


Ser Gly Ile Pro Asp Arg Gln Thr Val Gln Val Ile Gln Gln Ala Leu 
    50                  55                  60                  


His Arg Gln Pro Ser Thr Ala Ala Gln Tyr Leu Gln Gln Met Tyr Ala 
65                  70                  75                  80  


Ala Gln Gln Gln His Leu Met Leu Gln Thr Ala Ala Leu Gln Gln Gln 
                85                  90                  95      


His Leu Ser Ser Ala Gln Leu Gln Ser Leu Ala Ala Val Gln Gln Ala 
            100                 105                 110         


Ser Leu Val Ser Asn Arg Gln Gly Ser Thr Ser Gly Ser Asn Val Ser 
        115                 120                 125             


Ala Gln Ala Pro Ala Gln Ser Ser Ser Ile Asn Leu Ala Ala Ser Pro 
    130                 135                 140                 


Ala Ala Ala Gln Leu Leu Asn Arg Ala Gln Ser Val Asn Ser Ala Ala 
145                 150                 155                 160 


Ala Ser Gly Ile Ala Gln Gln Ala Val Leu Leu Gly Asn Thr Ser Ser 
                165                 170                 175     


Pro Ala Leu Thr Ala Ser Gln Ala Gln Met Tyr Leu Arg Ala Gln Met 
            180                 185                 190         


Leu Ile Phe Thr Pro Thr Ala Thr Val Ala Thr Val Gln Pro Glu Leu 
        195                 200                 205             


Gly Thr Gly Ser Pro Ala Arg Pro Pro Thr Pro Ala Gln Val Gln Asn 
    210                 215                 220                 


Leu Thr Leu Arg Thr Gln Gln Thr Pro Ala Ala Ala Ala Ser Gly Pro 
225                 230                 235                 240 


Thr Pro Thr Gln Pro Val Leu Pro Ser Leu Ala Leu Lys Pro Thr Pro 
                245                 250                 255     


Gly Gly Ser Gln Pro Leu Pro Thr Pro Ala Gln Ser Arg Asn Thr Ala 
            260                 265                 270         


Gln Ala Ser Pro Ala Gly Ala Lys Pro Gly Ile Ala Asp Ser Val Met 
        275                 280                 285             


Glu Pro His Lys Lys Gly Asp Gly Asn Ser Ser Val Pro Gly Ser Met 
    290                 295                 300                 


Glu Gly Arg Ala Gly Leu Ser Arg Thr Val Pro Ala Val Ala Ala His 
305                 310                 315                 320 


Pro Leu Ile Ala Pro Ala Tyr Ala Gln Leu Gln Pro His Gln Leu Leu 
                325                 330                 335     


Pro Gln Pro Ser Ser Lys His Leu Gln Pro Gln Phe Val Ile Gln Gln 
            340                 345                 350         


Gln Pro Gln Pro Gln Gln Gln Gln Pro Pro Pro Gln Gln Ser Arg Pro 
        355                 360                 365             


Val Leu Gln Ala Glu Pro His Pro Gln Leu Ala Ser Val Ser Pro Ser 
    370                 375                 380                 


Val Ala Leu Gln Pro Ser Ser Glu Ala His Ala Met Pro Leu Gly Pro 
385                 390                 395                 400 


Val Thr Pro Ala Leu Pro Leu Gln Cys Pro Thr Ala Asn Leu His Lys 
                405                 410                 415     


Pro Gly Gly Ser Gln Gln Cys His Pro Pro Thr Pro Asp Thr Gly Pro 
            420                 425                 430         


Gln Asn Gly His Pro Glu Gly Val Pro His Thr Pro Gln Arg Arg Phe 
        435                 440                 445             


Gln His Thr Ser Ala Val Ile Leu Gln Leu Gln Pro Ala Ser Pro Pro 
    450                 455                 460                 


Gln Gln Cys Val Pro Asp Asp Trp Lys Glu Val Ala Pro Gly Glu Lys 
465                 470                 475                 480 


Ser Val Pro Glu Thr Arg Ser Gly Pro Ser Pro His Gln Gln Ala Ile 
                485                 490                 495     


Val Thr Ala Met Pro Gly Gly Leu Pro Val Pro Thr Ser Pro Asn Ile 
            500                 505                 510         


Gln Pro Ser Pro Ala His Glu Thr Gly Gln Gly Ile Val His Ala Leu 
        515                 520                 525             


Thr Asp Leu Ser Ser Pro Gly Met Thr Ser Gly Asn Gly Asn Ser Ala 
    530                 535                 540                 


Ser Ser Ile Ala Gly Thr Ala Pro Gln Asn Gly Glu Asn Lys Pro Pro 
545                 550                 555                 560 


Gln Ala Ile Val Lys Pro Gln Ile Leu Thr His Val Ile Glu Gly Phe 
                565                 570                 575     


Val Ile Gln Glu Gly Ala Glu Pro Phe Pro Val Gly Arg Ser Ser Leu 
            580                 585                 590         


Leu Val Gly Asn Leu Lys Lys Lys Tyr Ala Gln Gly Phe Leu Pro Glu 
        595                 600                 605             


Lys Leu Pro Gln Gln Asp His Thr Thr Thr Thr Asp Ser Glu Met Glu 
    610                 615                 620                 


Glu Pro Tyr Leu Gln Glu Ser Lys Glu Glu Gly Ala Pro Leu Lys Leu 
625                 630                 635                 640 


Lys Cys Glu Leu Cys Gly Arg Val Asp Phe Ala Tyr Lys Phe Lys Arg 
                645                 650                 655     


Ser Lys Arg Phe Cys Ser Met Ala Cys Ala Lys Arg Tyr Asn Val Gly 
            660                 665                 670         


Cys Thr Lys Arg Val Gly Leu Phe His Ser Asp Arg Ser Lys Leu Gln 
        675                 680                 685             


Lys Ala Gly Ala Ala Thr His Asn Arg Arg Arg Ala Ser Lys Ala Ser 
    690                 695                 700                 


Leu Pro Pro Leu Thr Lys Asp Thr Lys Lys Gln Pro Thr Gly Thr Val 
705                 710                 715                 720 


Pro Leu Ser Val Thr Ala Ala Leu Gln Leu Thr His Ser Gln Glu Asp 
                725                 730                 735     


Ser Ser Arg Cys Ser Asp Asn Ser Ser Tyr Glu Glu Pro Leu Ser Pro 
            740                 745                 750         


Ile Ser Ala Ser Ser Ser Thr Ser Arg Arg Arg Gln Gly Gln Arg Asp 
        755                 760                 765             


Leu Glu Leu Pro Asp Met His Met Arg Asp Leu Val Gly Met Gly His 
    770                 775                 780                 


His Phe Leu Pro Ser Glu Pro Thr Lys Trp Asn Val Glu Asp Val Tyr 
785                 790                 795                 800 


Glu Phe Ile Arg Ser Leu Pro Gly Cys Gln Glu Ile Ala Glu Glu Phe 
                805                 810                 815     


Arg Ala Gln Glu Ile Asp Gly Gln Ala Leu Leu Leu Leu Lys Glu Asp 
            820                 825                 830         


His Leu Met Ser Ala Met Asn Ile Lys Leu Gly Pro Ala Leu Lys Ile 
        835                 840                 845             


Tyr Ala Arg Ile Ser Met Leu Lys Asp Ser 
    850                 855             


<210>  2898
<211>  95
<212>  PRT
<213>  homo sapiens

<400>  2898

Met Glu Leu Val Leu Val Phe Leu Cys Ser Leu Leu Ala Pro Met Val 
1               5                   10                  15      


Leu Ala Ser Ala Ala Glu Lys Glu Lys Glu Met Asp Pro Phe His Tyr 
            20                  25                  30          


Asp Tyr Gln Thr Leu Arg Ile Gly Gly Leu Val Phe Ala Val Val Leu 
        35                  40                  45              


Phe Ser Val Gly Ile Leu Leu Ile Leu Ser Arg Arg Cys Lys Cys Ser 
    50                  55                  60                  


Phe Asn Gln Lys Pro Arg Ala Pro Gly Asp Glu Glu Ala Gln Val Glu 
65                  70                  75                  80  


Asn Leu Ile Thr Ala Asn Ala Thr Glu Pro Gln Lys Ala Glu Asn 
                85                  90                  95  


<210>  2899
<211>  2186
<212>  PRT
<213>  homo sapiens

<400>  2899

Met Ala Gly Glu Arg Thr Arg Arg Phe Thr Arg Ser Leu Leu Arg Pro 
1               5                   10                  15      


Gly Gln Ala Ala Glu Leu Arg His Ser Ala Ala Ser Ala Ala Ala Val 
            20                  25                  30          


Ala Val Ser Ser Arg Gln Gln Gln Arg Gln Glu Lys Pro Arg Leu Leu 
        35                  40                  45              


Glu Pro Leu Asp Tyr Glu Thr Val Ile Glu Glu Leu Glu Lys Thr Tyr 
    50                  55                  60                  


Arg Asn Asp Pro Leu Gln Asp Leu Leu Phe Phe Pro Ser Asp Asp Phe 
65                  70                  75                  80  


Ser Ala Ala Thr Val Ser Trp Asp Ile Arg Thr Leu Tyr Ser Thr Val 
                85                  90                  95      


Pro Glu Asp Ala Glu His Lys Ala Glu Asn Leu Leu Val Lys Glu Ala 
            100                 105                 110         


Cys Lys Phe Tyr Ser Ser Gln Trp His Val Val Asn Tyr Lys Tyr Glu 
        115                 120                 125             


Gln Tyr Ser Gly Asp Ile Arg Gln Leu Pro Arg Ala Glu Tyr Lys Pro 
    130                 135                 140                 


Glu Lys Leu Pro Ser His Ser Phe Glu Ile Asp His Glu Asp Ala Asp 
145                 150                 155                 160 


Lys Asp Glu Asp Thr Thr Ser His Ser Ser Ser Lys Gly Gly Gly Gly 
                165                 170                 175     


Ala Gly Gly Thr Gly Val Phe Lys Ser Gly Trp Leu Tyr Lys Gly Asn 
            180                 185                 190         


Phe Asn Ser Thr Val Asn Asn Thr Val Thr Val Arg Ser Phe Lys Lys 
        195                 200                 205             


Arg Tyr Phe Gln Leu Thr Gln Leu Pro Asp Asn Ser Tyr Ile Met Asn 
    210                 215                 220                 


Phe Tyr Lys Asp Glu Lys Ile Ser Lys Glu Pro Lys Gly Cys Ile Phe 
225                 230                 235                 240 


Leu Asp Ser Cys Thr Gly Val Val Gln Asn Asn Arg Leu Arg Lys Tyr 
                245                 250                 255     


Ala Phe Glu Leu Lys Met Asn Asp Leu Thr Tyr Phe Val Leu Ala Ala 
            260                 265                 270         


Glu Thr Glu Ser Asp Met Asp Glu Trp Ile His Thr Leu Asn Arg Ile 
        275                 280                 285             


Leu Gln Ile Ser Pro Glu Gly Pro Leu Gln Gly Arg Arg Ser Thr Glu 
    290                 295                 300                 


Leu Thr Asp Leu Gly Leu Asp Ser Leu Asp Asn Ser Val Thr Cys Glu 
305                 310                 315                 320 


Cys Thr Pro Glu Glu Thr Asp Ser Ser Glu Asn Asn Leu His Ala Asp 
                325                 330                 335     


Phe Ala Lys Tyr Leu Thr Glu Thr Glu Asp Thr Val Lys Thr Thr Arg 
            340                 345                 350         


Asn Met Glu Arg Leu Asn Leu Phe Ser Leu Asp Pro Asp Ile Asp Thr 
        355                 360                 365             


Leu Lys Leu Gln Lys Lys Asp Leu Leu Glu Pro Glu Ser Val Ile Lys 
    370                 375                 380                 


Pro Phe Glu Glu Lys Ala Ala Lys Arg Ile Met Ile Ile Cys Lys Ala 
385                 390                 395                 400 


Leu Asn Ser Asn Leu Gln Gly Cys Val Thr Glu Asn Glu Asn Asp Pro 
                405                 410                 415     


Ile Thr Asn Ile Glu Pro Phe Phe Val Ser Val Ala Leu Tyr Asp Leu 
            420                 425                 430         


Arg Asp Ser Arg Lys Ile Ser Ala Asp Phe His Val Asp Leu Asn His 
        435                 440                 445             


Ala Ala Val Arg Gln Met Leu Leu Gly Ala Ser Val Ala Leu Glu Asn 
    450                 455                 460                 


Gly Asn Ile Asp Thr Ile Thr Pro Arg Gln Ser Glu Glu Pro His Ile 
465                 470                 475                 480 


Lys Gly Leu Pro Glu Glu Trp Leu Lys Phe Pro Lys Gln Ala Val Phe 
                485                 490                 495     


Ser Val Ser Asn Pro His Ser Glu Ile Val Leu Val Ala Lys Ile Glu 
            500                 505                 510         


Lys Val Leu Met Gly Asn Ile Ala Ser Gly Ala Glu Pro Tyr Ile Lys 
        515                 520                 525             


Asn Pro Asp Ser Asn Lys Tyr Ala Gln Lys Ile Leu Lys Ser Asn Arg 
    530                 535                 540                 


Gln Phe Cys Ser Lys Leu Gly Lys Tyr Arg Met Pro Phe Ala Trp Ala 
545                 550                 555                 560 


Val Arg Ser Val Phe Lys Asp Asn Gln Gly Asn Val Asp Arg Asp Ser 
                565                 570                 575     


Arg Phe Ser Pro Leu Phe Arg Gln Glu Ser Ser Lys Ile Ser Thr Glu 
            580                 585                 590         


Asp Leu Val Lys Leu Val Ser Asp Tyr Arg Arg Ala Asp Arg Ile Ser 
        595                 600                 605             


Lys Met Gln Thr Ile Pro Gly Ser Leu Asp Ile Ala Val Asp Asn Val 
    610                 615                 620                 


Pro Leu Glu His Pro Asn Cys Val Thr Ser Ser Phe Ile Pro Val Lys 
625                 630                 635                 640 


Pro Phe Asn Met Met Ala Gln Thr Glu Pro Thr Val Glu Val Glu Glu 
                645                 650                 655     


Phe Val Tyr Asp Ser Thr Lys Tyr Cys Arg Pro Tyr Arg Val Tyr Lys 
            660                 665                 670         


Asn Gln Ile Tyr Ile Tyr Pro Lys His Leu Lys Tyr Asp Ser Gln Lys 
        675                 680                 685             


Cys Phe Asn Lys Ala Arg Asn Ile Thr Val Cys Ile Glu Phe Lys Asn 
    690                 695                 700                 


Ser Asp Glu Glu Ser Ala Lys Pro Leu Lys Cys Ile Tyr Gly Lys Pro 
705                 710                 715                 720 


Gly Gly Pro Leu Phe Thr Ser Ala Ala Tyr Thr Ala Val Leu His His 
                725                 730                 735     


Ser Gln Asn Pro Asp Phe Ser Asp Glu Val Lys Ile Glu Leu Pro Thr 
            740                 745                 750         


Gln Leu His Glu Lys His His Ile Leu Phe Ser Phe Tyr His Val Thr 
        755                 760                 765             


Cys Asp Ile Asn Ala Lys Ala Asn Ala Lys Lys Lys Glu Ala Leu Glu 
    770                 775                 780                 


Thr Ser Val Gly Tyr Ala Trp Leu Pro Leu Met Lys His Asp Gln Ile 
785                 790                 795                 800 


Ala Ser Gln Glu Tyr Asn Ile Pro Ile Ala Thr Ser Leu Pro Pro Asn 
                805                 810                 815     


Tyr Leu Ser Phe Gln Asp Ser Ala Ser Gly Lys His Gly Gly Ser Asp 
            820                 825                 830         


Ile Lys Trp Val Asp Gly Gly Lys Pro Leu Phe Lys Val Ser Thr Phe 
        835                 840                 845             


Val Val Ser Thr Val Asn Thr Gln Asp Pro His Val Asn Ala Phe Phe 
    850                 855                 860                 


Gln Glu Cys Gln Lys Arg Glu Lys Asp Met Ser Gln Ser Pro Thr Ser 
865                 870                 875                 880 


Asn Phe Ile Arg Ser Cys Lys Asn Leu Leu Asn Val Glu Lys Ile His 
                885                 890                 895     


Ala Ile Met Ser Phe Leu Pro Ile Ile Leu Asn Gln Leu Phe Lys Val 
            900                 905                 910         


Leu Val Gln Asn Glu Glu Asp Glu Ile Thr Thr Thr Val Thr Arg Val 
        915                 920                 925             


Leu Thr Asp Ile Val Ala Lys Cys His Glu Glu Gln Leu Asp His Ser 
    930                 935                 940                 


Val Gln Ser Tyr Ile Lys Phe Val Phe Lys Thr Arg Ala Cys Lys Glu 
945                 950                 955                 960 


Arg Thr Val His Glu Glu Leu Ala Lys Asn Val Thr Gly Leu Leu Lys 
                965                 970                 975     


Ser Asn Asp Ser Thr Thr Val Lys His Val Leu Lys His Ser Trp Phe 
            980                 985                 990         


Phe Phe Ala Ile Ile Leu Lys Ser  Met Ala Gln His Leu  Ile Asp Thr 
        995                 1000                 1005             


Asn Lys  Ile Gln Leu Pro Arg  Pro Gln Arg Phe Pro  Glu Ser Tyr 
    1010                 1015                 1020             


Gln Asn  Glu Leu Asp Asn Leu  Val Met Val Leu Ser  Asp His Val 
    1025                 1030                 1035             


Ile Trp  Lys Tyr Lys Asp Ala  Leu Glu Glu Thr Arg  Arg Ala Asn 
    1040                 1045                 1050             


His Ser  Val Ala Arg Phe Leu  Lys Arg Cys Phe Thr  Phe Met Asp 
    1055                 1060                 1065             


Arg Gly  Tyr Val Phe Lys Met  Val Asn Asn Tyr Ile  Ser Met Phe 
    1070                 1075                 1080             


Ser Ser  Gly Asp Leu Lys Thr  Leu Cys Gln Tyr Lys  Phe Asp Phe 
    1085                 1090                 1095             


Leu Gln  Glu Val Cys Gln His  Glu His Phe Ile Pro  Leu Cys Leu 
    1100                 1105                 1110             


Pro Ile  Arg Ser Ala Asn Ile  Pro Asp Pro Leu Thr  Pro Ser Glu 
    1115                 1120                 1125             


Ser Thr  Gln Glu Leu His Ala  Ser Asp Met Pro Glu  Tyr Ser Val 
    1130                 1135                 1140             


Thr Asn  Glu Phe Cys Arg Lys  His Phe Leu Ile Gly  Ile Leu Leu 
    1145                 1150                 1155             


Arg Glu  Val Gly Phe Ala Leu  Gln Glu Asp Gln Asp  Val Arg His 
    1160                 1165                 1170             


Leu Ala  Leu Ala Val Leu Lys  Asn Leu Met Ala Lys  His Ser Phe 
    1175                 1180                 1185             


Asp Asp  Arg Tyr Arg Glu Pro  Arg Lys Gln Ala Gln  Ile Ala Ser 
    1190                 1195                 1200             


Leu Tyr  Met Pro Leu Tyr Gly  Met Leu Leu Asp Asn  Met Pro Arg 
    1205                 1210                 1215             


Ile Tyr  Leu Lys Asp Leu Tyr  Pro Phe Thr Val Asn  Thr Ser Asn 
    1220                 1225                 1230             


Gln Gly  Ser Arg Asp Asp Leu  Ser Thr Asn Gly Gly  Phe Gln Ser 
    1235                 1240                 1245             


Gln Thr  Ala Ile Lys His Ala  Asn Ser Val Asp Thr  Ser Phe Ser 
    1250                 1255                 1260             


Lys Asp  Val Leu Asn Ser Ile  Ala Ala Phe Ser Ser  Ile Ala Ile 
    1265                 1270                 1275             


Ser Thr  Val Asn His Ala Asp  Ser Arg Ala Ser Leu  Ala Ser Leu 
    1280                 1285                 1290             


Asp Ser  Asn Pro Ser Thr Asn  Glu Lys Ser Ser Glu  Lys Thr Asp 
    1295                 1300                 1305             


Asn Cys  Glu Lys Ile Pro Arg  Pro Leu Ser Leu Ile  Gly Ser Thr 
    1310                 1315                 1320             


Leu Arg  Phe Asp Lys Leu Asp  Gln Ala Glu Thr Arg  Ser Leu Leu 
    1325                 1330                 1335             


Met Cys  Phe Leu His Ile Met  Lys Thr Ile Ser Tyr  Glu Thr Leu 
    1340                 1345                 1350             


Ile Ala  Tyr Trp Gln Arg Ala  Pro Ser Pro Glu Val  Ser Asp Phe 
    1355                 1360                 1365             


Phe Ser  Ile Leu Asp Val Cys  Leu Gln Asn Phe Arg  Tyr Leu Gly 
    1370                 1375                 1380             


Lys Arg  Asn Ile Ile Arg Lys  Ile Ala Ala Ala Phe  Lys Phe Val 
    1385                 1390                 1395             


Gln Ser  Thr Gln Asn Asn Gly  Thr Leu Lys Gly Ser  Asn Pro Ser 
    1400                 1405                 1410             


Cys Gln  Thr Ser Gly Leu Leu  Ser Gln Trp Met His  Ser Thr Ser 
    1415                 1420                 1425             


Ser His  Glu Gly His Lys Gln  His Arg Ser Gln Thr  Leu Pro Ile 
    1430                 1435                 1440             


Ile Arg  Gly Lys Asn Ala Leu  Ser Asn Pro Lys Leu  Leu Gln Met 
    1445                 1450                 1455             


Leu Asp  Asn Thr Met Thr Ser  Asn Ser Asn Glu Ile  Asp Ile Val 
    1460                 1465                 1470             


His His  Val Asp Thr Glu Ala  Asn Ile Ala Thr Glu  Val Cys Leu 
    1475                 1480                 1485             


Thr Ile  Leu Asp Leu Leu Ser  Leu Phe Thr Gln Thr  His Gln Arg 
    1490                 1495                 1500             


Gln Leu  Gln Gln Cys Asp Cys  Gln Asn Ser Leu Met  Lys Arg Val 
    1505                 1510                 1515             


Phe Asp  Thr Tyr Met Leu Phe  Phe Gln Val Asn Gln  Ser Ala Thr 
    1520                 1525                 1530             


Ala Leu  Lys His Val Phe Ala  Ser Leu Arg Leu Phe  Val Cys Lys 
    1535                 1540                 1545             


Phe Pro  Ser Ala Phe Phe Gln  Gly Pro Ala Asp Leu  Cys Gly Ser 
    1550                 1555                 1560             


Phe Cys  Tyr Glu Val Leu Lys  Cys Cys Asn His Arg  Ser Arg Ser 
    1565                 1570                 1575             


Thr Gln  Thr Glu Ala Ser Ala  Leu Leu Tyr Phe Phe  Met Arg Lys 
    1580                 1585                 1590             


Asn Phe  Glu Phe Asn Lys Gln  Lys Ser Ile Val Arg  Ser His Leu 
    1595                 1600                 1605             


Gln Leu  Ile Lys Ala Val Ser  Gln Leu Ile Ala Asp  Ala Gly Ile 
    1610                 1615                 1620             


Gly Gly  Ser Arg Phe Gln His  Ser Leu Ala Ile Thr  Asn Asn Phe 
    1625                 1630                 1635             


Ala Asn  Gly Asp Lys Gln Met  Lys Asn Ser Asn Phe  Pro Ala Glu 
    1640                 1645                 1650             


Val Lys  Asp Leu Thr Lys Arg  Ile Arg Thr Val Leu  Met Ala Thr 
    1655                 1660                 1665             


Ala Gln  Met Lys Glu His Glu  Lys Asp Pro Glu Met  Leu Val Asp 
    1670                 1675                 1680             


Leu Gln  Tyr Ser Leu Ala Asn  Ser Tyr Ala Ser Thr  Pro Glu Leu 
    1685                 1690                 1695             


Arg Arg  Thr Trp Leu Glu Ser  Met Ala Lys Ile His  Ala Arg Asn 
    1700                 1705                 1710             


Gly Asp  Leu Ser Glu Ala Ala  Met Cys Tyr Ile His  Ile Ala Ala 
    1715                 1720                 1725             


Leu Ile  Ala Glu Tyr Leu Lys  Arg Lys Gly Tyr Trp  Lys Val Glu 
    1730                 1735                 1740             


Lys Ile  Cys Thr Ala Ser Leu  Leu Ser Glu Asp Thr  His Pro Cys 
    1745                 1750                 1755             


Asp Ser  Asn Ser Leu Leu Thr  Thr Pro Ser Gly Gly  Ser Met Phe 
    1760                 1765                 1770             


Ser Met  Gly Trp Pro Ala Phe  Leu Ser Ile Thr Pro  Asn Ile Lys 
    1775                 1780                 1785             


Glu Glu  Gly Ala Met Lys Glu  Asp Ser Gly Met Gln  Asp Thr Pro 
    1790                 1795                 1800             


Tyr Asn  Glu Asn Ile Leu Val  Glu Gln Leu Tyr Met  Cys Val Glu 
    1805                 1810                 1815             


Phe Leu  Trp Lys Ser Glu Arg  Tyr Glu Leu Ile Ala  Asp Val Asn 
    1820                 1825                 1830             


Lys Pro  Ile Ile Ala Val Phe  Glu Lys Gln Arg Asp  Phe Lys Lys 
    1835                 1840                 1845             


Leu Ser  Asp Leu Tyr Tyr Asp  Ile His Arg Ser Tyr  Leu Lys Val 
    1850                 1855                 1860             


Ala Glu  Val Val Asn Ser Glu  Lys Arg Leu Phe Gly  Arg Tyr Tyr 
    1865                 1870                 1875             


Arg Val  Ala Phe Tyr Gly Gln  Gly Phe Phe Glu Glu  Glu Glu Gly 
    1880                 1885                 1890             


Lys Glu  Tyr Ile Tyr Lys Glu  Pro Lys Leu Thr Gly  Leu Ser Glu 
    1895                 1900                 1905             


Ile Ser  Gln Arg Leu Leu Lys  Leu Tyr Ala Asp Lys  Phe Gly Ala 
    1910                 1915                 1920             


Asp Asn  Val Lys Ile Ile Gln  Asp Ser Asn Lys Val  Asn Pro Lys 
    1925                 1930                 1935             


Asp Leu  Asp Pro Lys Tyr Ala  Tyr Ile Gln Val Thr  Tyr Val Thr 
    1940                 1945                 1950             


Pro Phe  Phe Glu Glu Lys Glu  Ile Glu Asp Arg Lys  Thr Asp Phe 
    1955                 1960                 1965             


Glu Met  His His Asn Ile Asn  Arg Phe Val Phe Glu  Thr Pro Phe 
    1970                 1975                 1980             


Thr Leu  Ser Gly Lys Lys His  Gly Gly Val Ala Glu  Gln Cys Lys 
    1985                 1990                 1995             


Arg Arg  Thr Ile Leu Thr Thr  Ser His Leu Phe Pro  Tyr Val Lys 
    2000                 2005                 2010             


Lys Arg  Ile Gln Val Ile Ser  Gln Ser Ser Thr Glu  Leu Asn Pro 
    2015                 2020                 2025             


Ile Glu  Val Ala Ile Asp Glu  Met Ser Lys Lys Val  Ser Glu Leu 
    2030                 2035                 2040             


Asn Gln  Leu Cys Thr Met Glu  Glu Val Asp Met Ile  Arg Leu Gln 
    2045                 2050                 2055             


Leu Lys  Leu Gln Gly Ser Val  Ser Val Lys Val Asn  Ala Gly Pro 
    2060                 2065                 2070             


Met Ala  Tyr Ala Arg Ala Phe  Leu Glu Glu Thr Asn  Ala Lys Lys 
    2075                 2080                 2085             


Tyr Pro  Asp Asn Gln Val Lys  Leu Leu Lys Glu Ile  Phe Arg Gln 
    2090                 2095                 2100             


Phe Ala  Asp Ala Cys Gly Gln  Ala Leu Asp Val Asn  Glu Arg Leu 
    2105                 2110                 2115             


Ile Lys  Glu Asp Gln Leu Glu  Tyr Gln Glu Glu Leu  Arg Ser His 
    2120                 2125                 2130             


Tyr Lys  Asp Met Leu Ser Glu  Leu Ser Thr Val Met  Asn Glu Gln 
    2135                 2140                 2145             


Ile Thr  Gly Arg Asp Asp Leu  Ser Lys Arg Gly Val  Asp Gln Thr 
    2150                 2155                 2160             


Cys Thr  Arg Val Ile Ser Lys  Ala Thr Pro Ala Leu  Pro Thr Val 
    2165                 2170                 2175             


Ser Ile  Ser Ser Ser Ala Glu  Val 
    2180                 2185     


<210>  2900
<211>  369
<212>  PRT
<213>  homo sapiens

<400>  2900

Met Met Gln Pro Ser Leu Asp Ile Lys Pro Phe Met Ser Phe Pro Val 
1               5                   10                  15      


Asp Ser Ser Ser Ala Val Gly Leu Phe Pro Asn Phe Asn Thr Met Asp 
            20                  25                  30          


Pro Val Gln Lys Ala Val Ile Asn His Thr Phe Gly Val Ser Ile Pro 
        35                  40                  45              


Pro Lys Lys Lys Gln Val Ile Ser Cys Asn Val Cys Gln Leu Arg Phe 
    50                  55                  60                  


Asn Ser Asp Ser Gln Ala Glu Ala His Tyr Lys Gly Ser Lys His Ala 
65                  70                  75                  80  


Lys Lys Val Lys Ala Leu Asp Ala Thr Lys Asn Lys Pro Lys Met Val 
                85                  90                  95      


Pro Ser Lys Asp Ser Ala Lys Ala Asn Pro Ser Cys Ser Ile Thr Pro 
            100                 105                 110         


Ile Thr Gly Asn Asn Ser Asp Lys Ser Glu Asp Lys Gly Lys Leu Lys 
        115                 120                 125             


Ala Ser Ser Ser Ser Gln Pro Ser Ser Ser Glu Ser Gly Ser Phe Leu 
    130                 135                 140                 


Leu Lys Ser Gly Thr Thr Pro Leu Pro Pro Gly Ala Ala Thr Ser Pro 
145                 150                 155                 160 


Ser Lys Ser Thr Asn Gly Ala Pro Gly Thr Val Val Glu Ser Glu Glu 
                165                 170                 175     


Glu Lys Ala Lys Lys Leu Leu Tyr Cys Ser Leu Cys Lys Val Ala Val 
            180                 185                 190         


Asn Ser Leu Ser Gln Leu Glu Ala His Asn Thr Gly Ser Lys His Lys 
        195                 200                 205             


Thr Met Val Glu Ala Arg Asn Gly Ala Gly Pro Ile Lys Ser Tyr Pro 
    210                 215                 220                 


Arg Pro Gly Ser Arg Leu Lys Met Gln Asn Gly Ser Lys Gly Ser Gly 
225                 230                 235                 240 


Leu Gln Asn Lys Thr Phe His Cys Glu Ile Cys Asp Val His Val Asn 
                245                 250                 255     


Ser Glu Ile Gln Leu Lys Gln His Ile Ser Ser Arg Arg His Lys Asp 
            260                 265                 270         


Arg Val Ala Gly Lys Pro Leu Lys Pro Lys Tyr Ser Pro Tyr Asn Lys 
        275                 280                 285             


Leu Gln Arg Ser Pro Ser Ile Leu Ala Ala Lys Leu Ala Phe Gln Lys 
    290                 295                 300                 


Asp Met Met Lys Pro Leu Ala Pro Ala Phe Leu Ser Ser Pro Leu Ala 
305                 310                 315                 320 


Ala Ala Ala Ala Val Ser Ser Ala Leu Ser Leu Pro Pro Arg Pro Ser 
                325                 330                 335     


Ala Ser Leu Phe Gln Ala Pro Ala Ile Pro Pro Ala Leu Leu Arg Pro 
            340                 345                 350         


Gly His Gly Pro Ile Arg Ala Thr Pro Ala Ser Ile Leu Phe Ala Pro 
        355                 360                 365             


Tyr 
    


<210>  2901
<211>  478
<212>  PRT
<213>  homo sapiens

<400>  2901

Met Leu Ser Asp Glu Leu Glu Ser Lys Pro Glu Leu Leu Val Gln Phe 
1               5                   10                  15      


Val Gln Asn Thr Ser Ile Pro Leu Gly Gln Gly Leu Val Glu Ser Glu 
            20                  25                  30          


Ala Lys Asp Ile Thr Cys Leu Ser Leu Leu Pro Val Thr Glu Ala Ser 
        35                  40                  45              


Glu Cys Ser Arg Leu Met Leu Pro Asp Asp Thr Thr Asn His Ser Asn 
    50                  55                  60                  


Ser Ser Lys Glu Val Pro Ser Ser Ala Val Leu Arg Ser Leu Arg Val 
65                  70                  75                  80  


Asn Val Gly Pro Asp Gly Glu Glu Thr Arg Ala Gln Thr Val Gln Lys 
                85                  90                  95      


Ser Pro Glu Phe Leu Ser Thr Ser Glu Ser Ser Ser Leu Leu Gln Asp 
            100                 105                 110         


Leu Gln Pro Ser Asp Ser Thr Ser Phe Ile Leu Leu Asn Leu Thr Arg 
        115                 120                 125             


Ala Gly Leu Gly Ser Ser Ala Glu His Leu Val Phe Val Gln Asp Glu 
    130                 135                 140                 


Ala Glu Asp Ser Gly Asn Asp Phe Leu Ser Ser Glu Ser Thr Asp Ser 
145                 150                 155                 160 


Ser Ile Pro Trp Phe Leu Arg Val Gln Glu Leu Ala His Asp Ser Leu 
                165                 170                 175     


Ile Ala Ala Thr Arg Ala Gln Leu Ala Lys Asn Ala Lys Thr Ser Ser 
            180                 185                 190         


Asn Gly Glu Asn Val His Leu Gly Ser Gly Asp Gly Gln Ser Lys Asp 
        195                 200                 205             


Ser Gly Pro Leu Pro Gln Val Glu Lys Lys Leu Lys Cys Thr Val Glu 
    210                 215                 220                 


Gly Cys Asp Arg Thr Phe Val Trp Pro Ala His Phe Lys Tyr His Leu 
225                 230                 235                 240 


Lys Thr His Arg Asn Asp Arg Ser Phe Ile Cys Pro Ala Glu Gly Cys 
                245                 250                 255     


Gly Lys Ser Phe Tyr Val Leu Gln Arg Leu Lys Val His Met Arg Thr 
            260                 265                 270         


His Asn Gly Glu Lys Pro Phe Met Cys His Glu Ser Gly Cys Gly Lys 
        275                 280                 285             


Gln Phe Thr Thr Ala Gly Asn Leu Lys Asn His Arg Arg Ile His Thr 
    290                 295                 300                 


Gly Glu Lys Pro Phe Leu Cys Glu Ala Gln Gly Cys Gly Arg Ser Phe 
305                 310                 315                 320 


Ala Glu Tyr Ser Ser Leu Arg Lys His Leu Val Val His Ser Gly Glu 
                325                 330                 335     


Lys Pro His Gln Cys Gln Val Cys Gly Lys Thr Phe Ser Gln Ser Gly 
            340                 345                 350         


Ser Arg Asn Val His Met Arg Lys His His Leu Gln Leu Gly Ala Ala 
        355                 360                 365             


Gly Ser Gln Glu Gln Glu Gln Thr Ala Glu Pro Leu Met Gly Ser Ser 
    370                 375                 380                 


Leu Leu Glu Glu Ala Ser Val Pro Ser Lys Asn Leu Val Ser Met Asn 
385                 390                 395                 400 


Ser Gln Pro Ser Leu Gly Gly Glu Ser Leu Asn Leu Pro Asn Thr Asn 
                405                 410                 415     


Ser Ile Leu Gly Val Asp Asp Glu Val Leu Ala Glu Gly Ser Pro Arg 
            420                 425                 430         


Ser Leu Ser Ser Val Pro Asp Val Thr His His Leu Val Thr Met Gln 
        435                 440                 445             


Ser Gly Arg Gln Ser Tyr Glu Val Ser Val Leu Thr Ala Val Asn Pro 
    450                 455                 460                 


Gln Glu Leu Leu Asn Gln Gly Asp Leu Thr Glu Arg Arg Thr 
465                 470                 475             


<210>  2902
<211>  1284
<212>  PRT
<213>  homo sapiens

<400>  2902

Met His Lys Lys Arg Val Glu Glu Gly Glu Ala Ser Asp Phe Ser Leu 
1               5                   10                  15      


Ala Trp Asp Ser Ser Val Thr Ala Ala Gly Gly Leu Glu Gly Glu Pro 
            20                  25                  30          


Glu Cys Asp Gln Lys Thr Ser Arg Ala Leu Glu Asp Arg Asn Ser Val 
        35                  40                  45              


Thr Ser Gln Glu Glu Arg Asn Glu Asp Asp Glu Asp Met Glu Asp Glu 
    50                  55                  60                  


Ser Ile Tyr Thr Cys Asp His Cys Gln Gln Asp Phe Glu Ser Leu Ala 
65                  70                  75                  80  


Asp Leu Thr Asp His Arg Ala His Arg Cys Pro Gly Asp Gly Asp Asp 
                85                  90                  95      


Asp Pro Gln Leu Ser Trp Val Ala Ser Ser Pro Ser Ser Lys Asp Val 
            100                 105                 110         


Ala Ser Pro Thr Gln Met Ile Gly Asp Gly Cys Asp Leu Gly Leu Gly 
        115                 120                 125             


Glu Glu Glu Gly Gly Thr Gly Leu Pro Tyr Pro Cys Gln Phe Cys Asp 
    130                 135                 140                 


Lys Ser Phe Ile Arg Leu Ser Tyr Leu Lys Arg His Glu Gln Ile His 
145                 150                 155                 160 


Ser Asp Lys Leu Pro Phe Lys Cys Thr Tyr Cys Ser Arg Leu Phe Lys 
                165                 170                 175     


His Lys Arg Ser Arg Asp Arg His Ile Lys Leu His Thr Gly Asp Lys 
            180                 185                 190         


Lys Tyr His Cys His Glu Cys Glu Ala Ala Phe Ser Arg Ser Asp His 
        195                 200                 205             


Leu Lys Ile His Leu Lys Thr His Ser Ser Ser Lys Pro Phe Lys Cys 
    210                 215                 220                 


Thr Val Cys Lys Arg Gly Phe Ser Ser Thr Ser Ser Leu Gln Ser His 
225                 230                 235                 240 


Met Gln Ala His Lys Lys Asn Lys Glu His Leu Ala Lys Ser Glu Lys 
                245                 250                 255     


Glu Ala Lys Lys Asp Asp Phe Met Cys Asp Tyr Cys Glu Asp Thr Phe 
            260                 265                 270         


Ser Gln Thr Glu Glu Leu Glu Lys His Val Leu Thr Arg His Pro Gln 
        275                 280                 285             


Leu Ser Glu Lys Ala Asp Leu Gln Cys Ile His Cys Pro Glu Val Phe 
    290                 295                 300                 


Val Asp Glu Asn Thr Leu Leu Ala His Ile His Gln Ala His Ala Asn 
305                 310                 315                 320 


Gln Lys His Lys Cys Pro Met Cys Pro Glu Gln Phe Ser Ser Val Glu 
                325                 330                 335     


Gly Val Tyr Cys His Leu Asp Ser His Arg Gln Pro Asp Ser Ser Asn 
            340                 345                 350         


His Ser Val Ser Pro Asp Pro Val Leu Gly Ser Val Ala Ser Met Ser 
        355                 360                 365             


Ser Ala Thr Pro Asp Ser Ser Ala Ser Val Glu Arg Gly Ser Thr Pro 
    370                 375                 380                 


Asp Ser Thr Leu Lys Pro Leu Arg Gly Gln Lys Lys Met Arg Asp Asp 
385                 390                 395                 400 


Gly Gln Gly Trp Thr Lys Val Val Tyr Ser Cys Pro Tyr Cys Ser Lys 
                405                 410                 415     


Arg Asp Phe Asn Ser Leu Ala Val Leu Glu Ile His Leu Lys Thr Ile 
            420                 425                 430         


His Ala Asp Lys Pro Gln Gln Ser His Thr Cys Gln Ile Cys Leu Asp 
        435                 440                 445             


Ser Met Pro Thr Leu Tyr Asn Leu Asn Glu His Val Arg Lys Leu His 
    450                 455                 460                 


Lys Asn His Ala Tyr Pro Val Met Gln Phe Gly Asn Ile Ser Ala Phe 
465                 470                 475                 480 


His Cys Asn Tyr Cys Pro Glu Met Phe Ala Asp Ile Asn Ser Leu Gln 
                485                 490                 495     


Glu His Ile Arg Val Ser His Cys Gly Pro Asn Ala Asn Pro Ser Asp 
            500                 505                 510         


Gly Asn Asn Ala Phe Phe Cys Asn Gln Cys Ser Met Gly Phe Leu Thr 
        515                 520                 525             


Glu Ser Ser Leu Thr Glu His Ile Gln Gln Ala His Cys Ser Val Gly 
    530                 535                 540                 


Ser Ala Lys Leu Glu Ser Pro Val Val Gln Pro Thr Gln Ser Phe Met 
545                 550                 555                 560 


Glu Val Tyr Ser Cys Pro Tyr Cys Thr Asn Ser Pro Ile Phe Gly Ser 
                565                 570                 575     


Ile Leu Lys Leu Thr Lys His Ile Lys Glu Asn His Lys Asn Ile Pro 
            580                 585                 590         


Leu Ala His Ser Lys Lys Ser Lys Ala Glu Gln Ser Pro Val Ser Ser 
        595                 600                 605             


Asp Val Glu Val Ser Ser Pro Lys Arg Gln Arg Leu Ser Ala Ser Ala 
    610                 615                 620                 


Asn Ser Ile Ser Asn Gly Glu Tyr Pro Cys Asn Gln Cys Asp Leu Lys 
625                 630                 635                 640 


Phe Ser Asn Phe Glu Ser Phe Gln Thr His Leu Lys Leu His Leu Glu 
                645                 650                 655     


Leu Leu Leu Arg Lys Gln Ala Cys Pro Gln Cys Lys Glu Asp Phe Asp 
            660                 665                 670         


Ser Gln Glu Ser Leu Leu Gln His Leu Thr Val His Tyr Met Thr Thr 
        675                 680                 685             


Ser Thr His Tyr Val Cys Glu Ser Cys Asp Lys Gln Phe Ser Ser Val 
    690                 695                 700                 


Asp Asp Leu Gln Lys His Leu Leu Asp Met His Thr Phe Val Leu Tyr 
705                 710                 715                 720 


His Cys Thr Leu Cys Gln Glu Val Phe Asp Ser Lys Val Ser Ile Gln 
                725                 730                 735     


Val His Leu Ala Val Lys His Ser Asn Glu Lys Lys Met Tyr Arg Cys 
            740                 745                 750         


Thr Ala Cys Asn Trp Asp Phe Arg Lys Glu Ala Asp Leu Gln Val His 
        755                 760                 765             


Val Lys His Ser His Leu Gly Asn Pro Ala Lys Ala His Lys Cys Ile 
    770                 775                 780                 


Phe Cys Gly Glu Thr Phe Ser Thr Glu Val Glu Leu Gln Cys His Ile 
785                 790                 795                 800 


Thr Thr His Ser Lys Lys Tyr Asn Cys Lys Phe Cys Ser Lys Ala Phe 
                805                 810                 815     


His Ala Ile Ile Leu Leu Glu Lys His Leu Arg Glu Lys His Cys Val 
            820                 825                 830         


Phe Asp Ala Ala Thr Glu Asn Gly Thr Ala Asn Gly Val Pro Pro Met 
        835                 840                 845             


Ala Thr Lys Lys Ala Glu Pro Ala Asp Leu Gln Gly Met Leu Leu Lys 
    850                 855                 860                 


Asn Pro Glu Ala Pro Asn Ser His Glu Ala Ser Glu Asp Asp Val Asp 
865                 870                 875                 880 


Ala Ser Glu Pro Met Tyr Gly Cys Asp Ile Cys Gly Ala Ala Tyr Thr 
                885                 890                 895     


Met Glu Val Leu Leu Gln Asn His Arg Leu Arg Asp His Asn Ile Arg 
            900                 905                 910         


Pro Gly Glu Asp Asp Gly Ser Arg Lys Lys Ala Glu Phe Ile Lys Gly 
        915                 920                 925             


Ser His Lys Cys Asn Val Cys Ser Arg Thr Phe Phe Ser Glu Asn Gly 
    930                 935                 940                 


Leu Arg Glu His Leu Gln Thr His Arg Gly Pro Ala Lys His Tyr Met 
945                 950                 955                 960 


Cys Pro Ile Cys Gly Glu Arg Phe Pro Ser Leu Leu Thr Leu Thr Glu 
                965                 970                 975     


His Lys Val Thr His Ser Lys Ser Leu Asp Thr Gly Thr Cys Arg Ile 
            980                 985                 990         


Cys Lys Met Pro Leu Gln Ser Glu  Glu Glu Phe Ile Glu  His Cys Gln 
        995                 1000                 1005             


Met His  Pro Asp Leu Arg Asn  Ser Leu Thr Gly Phe  Arg Cys Val 
    1010                 1015                 1020             


Val Cys  Met Gln Thr Val Thr  Ser Thr Leu Glu Leu  Lys Ile His 
    1025                 1030                 1035             


Gly Thr  Phe His Met Gln Lys  Leu Ala Gly Ser Ser  Ala Ala Ser 
    1040                 1045                 1050             


Ser Pro  Asn Gly Gln Gly Leu  Gln Lys Leu Tyr Lys  Cys Ala Leu 
    1055                 1060                 1065             


Cys Leu  Lys Glu Phe Arg Ser  Lys Gln Asp Leu Val  Lys Leu Asp 
    1070                 1075                 1080             


Val Asn  Gly Leu Pro Tyr Gly  Leu Cys Ala Gly Cys  Met Ala Arg 
    1085                 1090                 1095             


Ser Ala  Asn Gly Gln Val Gly  Gly Leu Ala Pro Pro  Glu Pro Ala 
    1100                 1105                 1110             


Asp Arg  Pro Cys Ala Gly Leu  Arg Cys Pro Glu Cys  Ser Val Lys 
    1115                 1120                 1125             


Phe Glu  Ser Ala Glu Asp Leu  Glu Ser His Met Gln  Val Asp His 
    1130                 1135                 1140             


Arg Asp  Leu Thr Pro Glu Thr  Ser Gly Pro Arg Lys  Gly Thr Gln 
    1145                 1150                 1155             


Thr Ser  Pro Val Pro Arg Lys  Lys Thr Tyr Gln Cys  Ile Lys Cys 
    1160                 1165                 1170             


Gln Met  Thr Phe Glu Asn Glu  Arg Glu Ile Gln Ile  His Val Ala 
    1175                 1180                 1185             


Asn His  Met Ile Glu Glu Gly  Ile Asn His Glu Cys  Lys Leu Cys 
    1190                 1195                 1200             


Asn Gln  Met Phe Asp Ser Pro  Ala Lys Leu Leu Cys  His Leu Ile 
    1205                 1210                 1215             


Glu His  Ser Phe Glu Gly Met  Gly Gly Thr Phe Lys  Cys Pro Val 
    1220                 1225                 1230             


Cys Phe  Thr Val Phe Val Gln  Ala Asn Lys Leu Gln  Gln His Ile 
    1235                 1240                 1245             


Phe Ala  Val His Gly Gln Glu  Asp Lys Ile Tyr Asp  Cys Ser Gln 
    1250                 1255                 1260             


Cys Pro  Gln Lys Phe Phe Phe  Gln Thr Glu Leu Gln  Asn His Thr 
    1265                 1270                 1275             


Met Ser  Gln His Ala Gln 
    1280                 


<210>  2903
<211>  708
<212>  PRT
<213>  homo sapiens

<400>  2903

Met Thr Glu Arg Arg Arg Asp Glu Leu Ser Glu Glu Ile Asn Asn Leu 
1               5                   10                  15      


Arg Glu Lys Val Met Lys Gln Ser Glu Glu Asn Asn Asn Leu Gln Ser 
            20                  25                  30          


Gln Val Gln Lys Leu Thr Glu Glu Asn Thr Thr Leu Arg Glu Gln Val 
        35                  40                  45              


Glu Pro Thr Pro Glu Asp Glu Asp Asp Asp Ile Glu Leu Arg Gly Ala 
    50                  55                  60                  


Ala Ala Ala Ala Ala Pro Pro Pro Pro Ile Glu Glu Glu Cys Pro Glu 
65                  70                  75                  80  


Asp Leu Pro Glu Lys Phe Asp Gly Asn Pro Asp Met Leu Ala Pro Phe 
                85                  90                  95      


Met Ala Gln Cys Gln Ile Phe Met Glu Lys Ser Thr Arg Asp Phe Ser 
            100                 105                 110         


Val Asp Arg Val Arg Val Cys Phe Val Thr Ser Met Met Thr Gly Arg 
        115                 120                 125             


Ala Ala Arg Trp Ala Ser Ala Lys Leu Glu Arg Ser His Tyr Leu Met 
    130                 135                 140                 


His Asn Tyr Pro Ala Phe Met Met Glu Met Lys His Val Phe Glu Asp 
145                 150                 155                 160 


Pro Gln Arg Arg Glu Val Ala Lys Arg Lys Ile Arg Arg Leu Arg Gln 
                165                 170                 175     


Gly Met Gly Ser Val Ile Asp Tyr Ser Asn Ala Phe Gln Met Ile Ala 
            180                 185                 190         


Gln Asp Leu Asp Trp Asn Glu Pro Ala Leu Ile Asp Gln Tyr His Glu 
        195                 200                 205             


Gly Leu Ser Asp His Ile Gln Glu Glu Leu Ser His Leu Glu Val Ala 
    210                 215                 220                 


Lys Ser Leu Ser Ala Leu Ile Gly Gln Cys Ile His Ile Glu Arg Arg 
225                 230                 235                 240 


Leu Ala Arg Ala Ala Ala Ala Arg Lys Pro Arg Ser Pro Pro Arg Ala 
                245                 250                 255     


Leu Val Leu Pro His Ile Ala Ser His His Gln Val Asp Pro Thr Glu 
            260                 265                 270         


Pro Val Gly Gly Ala Arg Met Arg Leu Thr Gln Glu Glu Lys Glu Arg 
        275                 280                 285             


Arg Arg Lys Leu Asn Leu Cys Leu Tyr Cys Gly Thr Gly Gly His Tyr 
    290                 295                 300                 


Ala Asp Asn Cys Pro Ala Lys Ala Ser Lys Ser Ser Pro Ala Gly Lys 
305                 310                 315                 320 


Leu Pro Gly Pro Ala Val Glu Gly Pro Ser Ala Thr Gly Pro Glu Ile 
                325                 330                 335     


Ile Arg Ser Pro Gln Asp Asp Ala Ser Ser Pro His Leu Gln Val Met 
            340                 345                 350         


Leu Gln Ile His Leu Pro Gly Arg His Thr Leu Phe Val Arg Ala Met 
        355                 360                 365             


Ile Asp Ser Gly Ala Ser Gly Asn Phe Ile Asp His Glu Tyr Val Ala 
    370                 375                 380                 


Gln Asn Gly Ile Pro Leu Arg Ile Lys Asp Trp Pro Ile Leu Val Glu 
385                 390                 395                 400 


Ala Ile Asp Gly Arg Pro Ile Ala Ser Gly Pro Val Val His Glu Thr 
                405                 410                 415     


His Asp Leu Ile Val Asp Leu Gly Asp His Arg Glu Val Leu Ser Phe 
            420                 425                 430         


Asp Val Thr Gln Ser Pro Phe Phe Pro Val Val Leu Gly Val Arg Trp 
        435                 440                 445             


Leu Ser Thr His Asp Pro Asn Ile Thr Trp Ser Thr Arg Ser Ile Val 
    450                 455                 460                 


Phe Asp Ser Glu Tyr Cys Arg Tyr His Cys Arg Met Tyr Ser Pro Ile 
465                 470                 475                 480 


Pro Pro Ser Leu Pro Pro Pro Ala Pro Gln Pro Pro Leu Tyr Tyr Pro 
                485                 490                 495     


Val Asp Gly Tyr Arg Val Tyr Gln Pro Val Arg Tyr Tyr Tyr Val Gln 
            500                 505                 510         


Asn Val Tyr Thr Pro Val Asp Glu His Val Tyr Pro Asp His Arg Leu 
        515                 520                 525             


Val Asp Pro His Ile Glu Met Ile Pro Gly Ala His Ser Ile Pro Ser 
    530                 535                 540                 


Gly His Val Tyr Ser Leu Ser Glu Pro Glu Met Ala Ala Leu Arg Asp 
545                 550                 555                 560 


Phe Val Ala Arg Asn Val Lys Asp Gly Leu Ile Thr Pro Thr Ile Ala 
                565                 570                 575     


Pro Asn Gly Ala Gln Val Leu Gln Val Lys Arg Gly Trp Lys Leu Gln 
            580                 585                 590         


Val Ser Tyr Asp Cys Arg Ala Pro Asn Asn Phe Thr Ile Gln Asn Gln 
        595                 600                 605             


Tyr Pro Arg Leu Ser Ile Pro Asn Leu Glu Asp Gln Ala His Leu Ala 
    610                 615                 620                 


Thr Tyr Thr Glu Phe Val Pro Gln Ile Pro Gly Tyr Gln Thr Tyr Pro 
625                 630                 635                 640 


Thr Tyr Ala Ala Tyr Pro Thr Tyr Pro Val Gly Phe Ala Trp Tyr Pro 
                645                 650                 655     


Val Gly Arg Asp Gly Gln Gly Arg Ser Leu Tyr Val Pro Val Met Ile 
            660                 665                 670         


Thr Trp Asn Pro His Trp Tyr Arg Gln Pro Pro Val Pro Gln Tyr Pro 
        675                 680                 685             


Pro Pro Gln Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro Ser 
    690                 695                 700                 


Tyr Ser Thr Leu 
705             


<210>  2904
<211>  134
<212>  PRT
<213>  homo sapiens

<400>  2904

Met Ala Ala Thr Met Lys Lys Ala Ala Ala Glu Asp Val Asn Val Thr 
1               5                   10                  15      


Phe Glu Asp Gln Gln Lys Ile Asn Lys Phe Ala Arg Asn Thr Ser Arg 
            20                  25                  30          


Ile Thr Glu Leu Lys Glu Glu Ile Glu Val Lys Lys Lys Gln Leu Gln 
        35                  40                  45              


Asn Leu Glu Asp Ala Cys Asp Asp Ile Met Leu Ala Asp Asp Asp Cys 
    50                  55                  60                  


Leu Met Ile Pro Tyr Gln Ile Gly Asp Val Phe Ile Ser His Ser Gln 
65                  70                  75                  80  


Glu Glu Thr Gln Glu Met Leu Glu Glu Ala Lys Lys Asn Leu Gln Glu 
                85                  90                  95      


Glu Ile Asp Ala Leu Glu Ser Arg Val Glu Ser Ile Gln Arg Val Leu 
            100                 105                 110         


Ala Asp Leu Lys Val Gln Leu Tyr Ala Lys Phe Gly Ser Asn Ile Asn 
        115                 120                 125             


Leu Glu Ala Asp Glu Ser 
    130                 


<210>  2905
<211>  922
<212>  PRT
<213>  homo sapiens

<400>  2905

Met Phe Leu His Ser Val Asn Leu Trp Asn Leu Ala Phe Tyr Val Phe 
1               5                   10                  15      


Met Val Phe Leu Ala Thr Leu Gly Leu Trp Asp Val Phe Phe Gly Phe 
            20                  25                  30          


Glu Glu Asn Lys Cys Ser Met Ser Tyr Met Phe Glu Tyr Pro Glu Tyr 
        35                  40                  45              


Gln Lys Ile Glu Leu Pro Lys Lys Leu Ala Lys Arg Tyr Pro Ala Tyr 
    50                  55                  60                  


Glu Leu Tyr Leu Tyr Gly Glu Gly Ser Tyr Ala Glu Glu His Lys Ile 
65                  70                  75                  80  


Leu Pro Leu Thr Gly Ile Pro Val Leu Phe Leu Pro Gly Asn Ala Gly 
                85                  90                  95      


Ser Tyr Lys Gln Val Arg Ser Ile Gly Ser Ile Ala Leu Arg Lys Ala 
            100                 105                 110         


Glu Asp Ile Asp Phe Lys Tyr His Phe Asp Phe Phe Ser Val Asn Phe 
        115                 120                 125             


Asn Glu Glu Leu Val Ala Leu Tyr Gly Gly Ser Leu Gln Lys Gln Thr 
    130                 135                 140                 


Lys Phe Val His Glu Cys Ile Lys Thr Ile Leu Lys Leu Tyr Lys Gly 
145                 150                 155                 160 


Gln Glu Phe Ala Pro Lys Ser Val Ala Ile Ile Gly His Ser Met Gly 
                165                 170                 175     


Gly Leu Val Ala Arg Ala Leu Leu Thr Leu Lys Asn Phe Lys His Asp 
            180                 185                 190         


Leu Ile Asn Leu Leu Ile Thr Gln Ala Thr Pro His Val Ala Pro Val 
        195                 200                 205             


Met Pro Leu Asp Arg Phe Ile Thr Asp Phe Tyr Thr Thr Val Asn Asn 
    210                 215                 220                 


Tyr Trp Ile Leu Asn Ala Arg His Ile Asn Leu Thr Thr Leu Ser Val 
225                 230                 235                 240 


Ala Gly Gly Phe Arg Asp Tyr Gln Val Arg Ser Gly Leu Thr Phe Leu 
                245                 250                 255     


Pro Lys Leu Ser His His Thr Ser Ala Leu Ser Val Val Ser Ser Ala 
            260                 265                 270         


Val Pro Lys Thr Trp Val Ser Thr Asp His Leu Ser Ile Val Trp Cys 
        275                 280                 285             


Lys Gln Leu Gln Leu Thr Thr Val Arg Ala Phe Phe Asp Leu Ile Asp 
    290                 295                 300                 


Ala Asp Thr Lys Gln Ile Thr Gln Asn Ser Lys Lys Lys Leu Ser Val 
305                 310                 315                 320 


Leu Tyr His His Phe Ile Arg His Pro Ser Lys His Phe Glu Glu Asn 
                325                 330                 335     


Pro Ala Ile Ile Ser Asp Leu Thr Gly Thr Ser Met Trp Val Leu Val 
            340                 345                 350         


Lys Val Ser Lys Trp Thr Tyr Val Ala Tyr Asn Glu Ser Glu Lys Ile 
        355                 360                 365             


Tyr Phe Thr Phe Pro Leu Glu Asn His Arg Lys Ile Tyr Thr His Val 
    370                 375                 380                 


Tyr Cys Gln Ser Thr Met Leu Asp Thr Asn Ser Trp Ile Phe Ala Cys 
385                 390                 395                 400 


Ile Asn Ser Thr Ser Met Cys Leu Gln Gly Val Asp Leu Ser Trp Lys 
                405                 410                 415     


Ala Glu Leu Leu Pro Thr Ile Lys Tyr Leu Thr Leu Arg Leu Gln Asp 
            420                 425                 430         


Tyr Pro Ser Leu Ser His Leu Val Val Tyr Val Pro Ser Val Arg Gly 
        435                 440                 445             


Ser Lys Phe Val Val Asp Cys Glu Phe Phe Lys Lys Glu Lys Arg Tyr 
    450                 455                 460                 


Ile Gln Leu Pro Val Thr His Leu Phe Ser Phe Gly Leu Ser Ser Arg 
465                 470                 475                 480 


Lys Val Val Leu Asn Thr Asn Gly Leu Tyr Tyr Asn Leu Glu Leu Leu 
                485                 490                 495     


Asn Phe Gly Gln Ile Tyr Gln Ala Phe Lys Ile Asn Val Val Ser Lys 
            500                 505                 510         


Cys Ser Ala Val Lys Glu Glu Ile Thr Ser Ile Tyr Arg Leu His Ile 
        515                 520                 525             


Pro Trp Ser Tyr Glu Asp Ser Leu Thr Ile Ala Gln Ala Pro Ser Ser 
    530                 535                 540                 


Thr Glu Ile Ser Leu Lys Leu His Ile Ala Gln Pro Glu Asn Asn Thr 
545                 550                 555                 560 


His Val Ala Leu Phe Lys Met Tyr Thr Ser Ser Asp Cys Arg Tyr Glu 
                565                 570                 575     


Val Thr Val Lys Thr Ser Phe Ser Gln Ile Leu Gly Gln Val Val Arg 
            580                 585                 590         


Phe His Gly Gly Ala Leu Pro Ala Tyr Val Val Ser Asn Ile Leu Leu 
        595                 600                 605             


Ala Tyr Arg Gly Gln Leu Tyr Ser Leu Phe Ser Thr Gly Cys Cys Leu 
    610                 615                 620                 


Glu Tyr Ala Thr Met Leu Asp Lys Glu Ala Lys Pro Tyr Lys Val Asp 
625                 630                 635                 640 


Pro Phe Val Ile Ile Ile Lys Phe Leu Leu Gly Tyr Lys Trp Phe Lys 
                645                 650                 655     


Glu Leu Trp Asp Val Leu Leu Leu Pro Glu Leu Asp Ala Val Ile Leu 
            660                 665                 670         


Thr Cys Gln Ser Met Cys Phe Pro Leu Ile Ser Leu Ile Leu Phe Leu 
        675                 680                 685             


Phe Gly Thr Cys Thr Ala Tyr Trp Ser Gly Leu Leu Ser Ser Ala Ser 
    690                 695                 700                 


Val Arg Leu Leu Ser Ser Leu Trp Leu Ala Leu Lys Arg Pro Ser Glu 
705                 710                 715                 720 


Leu Pro Lys Asp Ile Lys Met Ile Ser Pro Asp Leu Pro Phe Leu Thr 
                725                 730                 735     


Ile Val Leu Ile Ile Val Ser Trp Thr Thr Cys Gly Ala Leu Ala Ile 
            740                 745                 750         


Leu Leu Ser Tyr Leu Tyr Tyr Val Phe Lys Val Val His Leu Gln Ala 
        755                 760                 765             


Ser Leu Thr Thr Phe Lys Asn Ser Gln Pro Val Asn Pro Lys His Ser 
    770                 775                 780                 


Arg Arg Ser Glu Lys Lys Ser Asn His His Lys Asp Ser Ser Ile His 
785                 790                 795                 800 


His Leu Arg Leu Ser Ala Asn Asp Ala Glu Asp Ser Leu Arg Met His 
                805                 810                 815     


Ser Thr Val Ile Asn Leu Leu Thr Trp Ile Val Leu Leu Ser Met Pro 
            820                 825                 830         


Ser Leu Ile Tyr Trp Leu Lys Asn Leu Arg Tyr Tyr Phe Lys Leu Asn 
        835                 840                 845             


Pro Asp Pro Cys Lys Pro Leu Ala Phe Ile Leu Ile Pro Thr Met Ala 
    850                 855                 860                 


Ile Leu Gly Asn Thr Tyr Thr Val Ser Ile Lys Ser Ser Lys Leu Leu 
865                 870                 875                 880 


Lys Thr Thr Ser Gln Phe Pro Leu Pro Leu Ala Val Gly Val Ile Ala 
                885                 890                 895     


Phe Gly Ser Ala His Leu Tyr Arg Leu Pro Cys Phe Val Phe Ile Pro 
            900                 905                 910         


Leu Leu Leu His Ala Leu Cys Asn Phe Met 
        915                 920         


<210>  2906
<211>  1042
<212>  PRT
<213>  homo sapiens

<400>  2906

Met Lys Ser Glu Asp Tyr Pro His Glu Thr Met Ala Pro Asp Ile His 
1               5                   10                  15      


Glu Glu Arg Gln Tyr Arg Cys Glu Asp Cys Asp Gln Leu Phe Glu Ser 
            20                  25                  30          


Lys Ala Glu Leu Ala Asp His Gln Lys Phe Pro Cys Ser Thr Pro His 
        35                  40                  45              


Ser Ala Phe Ser Met Val Glu Glu Asp Phe Gln Gln Lys Leu Glu Ser 
    50                  55                  60                  


Glu Asn Asp Leu Gln Glu Ile His Thr Ile Gln Glu Cys Lys Glu Cys 
65                  70                  75                  80  


Asp Gln Val Phe Pro Asp Leu Gln Ser Leu Glu Lys His Met Leu Ser 
                85                  90                  95      


His Thr Glu Glu Arg Glu Tyr Lys Cys Asp Gln Cys Pro Lys Ala Phe 
            100                 105                 110         


Asn Trp Lys Ser Asn Leu Ile Arg His Gln Met Ser His Asp Ser Gly 
        115                 120                 125             


Lys His Tyr Glu Cys Glu Asn Cys Ala Lys Val Phe Thr Asp Pro Ser 
    130                 135                 140                 


Asn Leu Gln Arg His Ile Arg Ser Gln His Val Gly Ala Arg Ala His 
145                 150                 155                 160 


Ala Cys Pro Glu Cys Gly Lys Thr Phe Ala Thr Ser Ser Gly Leu Lys 
                165                 170                 175     


Gln His Lys His Ile His Ser Ser Val Lys Pro Phe Ile Cys Glu Val 
            180                 185                 190         


Cys His Lys Ser Tyr Thr Gln Phe Ser Asn Leu Cys Arg His Lys Arg 
        195                 200                 205             


Met His Ala Asp Cys Arg Thr Gln Ile Lys Cys Lys Asp Cys Gly Gln 
    210                 215                 220                 


Met Phe Ser Thr Thr Ser Ser Leu Asn Lys His Arg Arg Phe Cys Glu 
225                 230                 235                 240 


Gly Lys Asn His Phe Ala Ala Gly Gly Phe Phe Gly Gln Gly Ile Ser 
                245                 250                 255     


Leu Pro Gly Thr Pro Ala Met Asp Lys Thr Ser Met Val Asn Met Ser 
            260                 265                 270         


His Ala Asn Pro Gly Leu Ala Asp Tyr Phe Gly Ala Asn Arg His Pro 
        275                 280                 285             


Ala Gly Leu Thr Phe Pro Thr Ala Pro Gly Phe Ser Phe Ser Phe Pro 
    290                 295                 300                 


Gly Leu Phe Pro Ser Gly Leu Tyr His Arg Pro Pro Leu Ile Pro Ala 
305                 310                 315                 320 


Ser Ser Pro Val Lys Gly Leu Ser Ser Thr Glu Gln Thr Asn Lys Ser 
                325                 330                 335     


Gln Ser Pro Leu Met Thr His Pro Gln Ile Leu Pro Ala Thr Gln Asp 
            340                 345                 350         


Ile Leu Lys Ala Leu Ser Lys His Pro Ser Val Gly Asp Asn Lys Pro 
        355                 360                 365             


Val Glu Leu Gln Pro Glu Arg Ser Ser Glu Glu Arg Pro Phe Glu Lys 
    370                 375                 380                 


Ile Ser Asp Gln Ser Glu Ser Ser Asp Leu Asp Asp Val Ser Thr Pro 
385                 390                 395                 400 


Ser Gly Ser Asp Leu Glu Thr Thr Ser Gly Ser Asp Leu Glu Ser Asp 
                405                 410                 415     


Ile Glu Ser Asp Lys Glu Lys Phe Lys Glu Asn Gly Lys Met Phe Lys 
            420                 425                 430         


Asp Lys Val Ser Pro Leu Gln Asn Leu Ala Ser Ile Asn Asn Lys Lys 
        435                 440                 445             


Glu Tyr Ser Asn His Ser Ile Phe Ser Pro Ser Leu Glu Glu Gln Thr 
    450                 455                 460                 


Ala Val Ser Gly Ala Val Asn Asp Ser Ile Lys Ala Ile Ala Ser Ile 
465                 470                 475                 480 


Ala Glu Lys Tyr Phe Gly Ser Thr Gly Leu Val Gly Leu Gln Asp Lys 
                485                 490                 495     


Lys Val Gly Ala Leu Pro Tyr Pro Ser Met Phe Pro Leu Pro Phe Phe 
            500                 505                 510         


Pro Ala Phe Ser Gln Ser Met Tyr Pro Phe Pro Asp Arg Asp Leu Arg 
        515                 520                 525             


Ser Leu Pro Leu Lys Met Glu Pro Gln Ser Pro Gly Glu Val Lys Lys 
    530                 535                 540                 


Leu Gln Lys Gly Ser Ser Glu Ser Pro Phe Asp Leu Thr Thr Lys Arg 
545                 550                 555                 560 


Lys Asp Glu Lys Pro Leu Thr Pro Val Pro Ser Lys Pro Pro Val Thr 
                565                 570                 575     


Pro Ala Thr Ser Gln Asp Gln Pro Leu Asp Leu Ser Met Gly Ser Arg 
            580                 585                 590         


Ser Arg Ala Ser Gly Thr Lys Leu Thr Glu Pro Arg Lys Asn His Val 
        595                 600                 605             


Phe Gly Gly Lys Lys Gly Ser Asn Val Glu Ser Arg Pro Ala Ser Asp 
    610                 615                 620                 


Gly Ser Leu Gln His Ala Arg Pro Thr Pro Phe Phe Met Asp Pro Ile 
625                 630                 635                 640 


Tyr Arg Val Glu Lys Arg Lys Leu Thr Asp Pro Leu Glu Ala Leu Lys 
                645                 650                 655     


Glu Lys Tyr Leu Arg Pro Ser Pro Gly Phe Leu Phe His Pro Gln Met 
            660                 665                 670         


Ser Ala Ile Glu Asn Met Ala Glu Lys Leu Glu Ser Phe Ser Ala Leu 
        675                 680                 685             


Lys Pro Glu Ala Ser Glu Leu Leu Gln Ser Val Pro Ser Met Phe Asn 
    690                 695                 700                 


Phe Arg Ala Pro Pro Asn Ala Leu Pro Glu Asn Leu Leu Arg Lys Gly 
705                 710                 715                 720 


Lys Glu Arg Tyr Thr Cys Arg Tyr Cys Gly Lys Ile Phe Pro Arg Ser 
                725                 730                 735     


Ala Asn Leu Thr Arg His Leu Arg Thr His Thr Gly Glu Gln Pro Tyr 
            740                 745                 750         


Arg Cys Lys Tyr Cys Asp Arg Ser Phe Ser Ile Ser Ser Asn Leu Gln 
        755                 760                 765             


Arg His Val Arg Asn Ile His Asn Lys Glu Lys Pro Phe Lys Cys His 
    770                 775                 780                 


Leu Cys Asp Arg Cys Phe Gly Gln Gln Thr Asn Leu Asp Arg His Leu 
785                 790                 795                 800 


Lys Lys His Glu Asn Gly Asn Met Ser Gly Thr Ala Thr Ser Ser Pro 
                805                 810                 815     


His Ser Glu Leu Glu Ser Thr Gly Ala Ile Leu Asp Asp Lys Glu Asp 
            820                 825                 830         


Ala Tyr Phe Thr Glu Ile Arg Asn Phe Ile Gly Asn Ser Asn His Gly 
        835                 840                 845             


Ser Gln Ser Pro Arg Asn Val Glu Glu Arg Met Asn Gly Ser His Phe 
    850                 855                 860                 


Lys Asp Glu Lys Ala Leu Val Thr Ser Gln Asn Ser Asp Leu Leu Asp 
865                 870                 875                 880 


Asp Glu Glu Val Glu Asp Glu Val Leu Leu Asp Glu Glu Asp Glu Asp 
                885                 890                 895     


Asn Asp Ile Thr Gly Lys Thr Gly Lys Glu Pro Val Thr Ser Asn Leu 
            900                 905                 910         


His Glu Gly Asn Pro Glu Asp Asp Tyr Glu Glu Thr Ser Ala Leu Glu 
        915                 920                 925             


Met Ser Cys Lys Thr Ser Pro Val Arg Tyr Lys Glu Glu Glu Tyr Lys 
    930                 935                 940                 


Ser Gly Leu Ser Ala Leu Asp His Ile Arg His Phe Thr Asp Ser Leu 
945                 950                 955                 960 


Lys Met Arg Lys Met Glu Asp Asn Gln Tyr Ser Glu Ala Glu Leu Ser 
                965                 970                 975     


Ser Phe Ser Thr Ser His Val Pro Glu Glu Leu Lys Gln Pro Leu His 
            980                 985                 990         


Arg Lys Ser Lys Ser Gln Ala Tyr  Ala Met Met Leu Ser  Leu Ser Asp 
        995                 1000                 1005             


Lys Glu  Ser Leu His Ser Thr  Ser His Ser Ser Ser  Asn Val Trp 
    1010                 1015                 1020             


His Ser  Met Ala Arg Ala Ala  Ala Glu Ser Ser Ala  Ile Gln Ser 
    1025                 1030                 1035             


Ile Ser  His Val 
    1040         


<210>  2907
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  2907

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  2908
<211>  207
<212>  PRT
<213>  homo sapiens

<400>  2908

Met Ser Glu Ala Val Arg Val Pro Ser Pro Ala Thr Pro Leu Val Val 
1               5                   10                  15      


Ala Ala Ala Ala Pro Glu Glu Arg Lys Gly Lys Glu Ser Glu Arg Glu 
            20                  25                  30          


Lys Leu Pro Pro Ile Val Ser Ala Gly Ala Gly Ala Thr Ala Gly Leu 
        35                  40                  45              


Asp Arg Gly Ala Lys Gly Gln Ile Ser Thr Phe Ser Ser Phe Ile Ser 
    50                  55                  60                  


Ala Val Ser Pro Lys Lys Glu Ala Ala Glu Asn Arg Ser Ser Pro Ala 
65                  70                  75                  80  


His Leu Val Phe Pro Asn Ile Lys Asn Val Arg Glu Pro Pro Pro Ile 
                85                  90                  95      


Cys Leu Asp Val Arg Gln Lys Gln Arg Thr Ser Met Asp Ala Ser Ser 
            100                 105                 110         


Ser Glu Met Lys Ala Pro Val Leu Pro Glu Pro Ile Leu Pro Ile Gln 
        115                 120                 125             


Pro Lys Thr Val Lys Asp Phe Gln Glu Asp Val Glu Lys Val Lys Ser 
    130                 135                 140                 


Ser Gly Asp Trp Lys Ala Val His Asp Phe Tyr Leu Thr Thr Phe Asp 
145                 150                 155                 160 


Ser Phe Pro Glu Leu Asn Ala Ala Phe Lys Lys Asp Ala Thr Ala Ser 
                165                 170                 175     


Phe Asn Thr Ile Glu Asp Ser Gly Ile Asn Ala Lys Phe Val Asn Ala 
            180                 185                 190         


Val Tyr Asp Thr Leu Leu Asn Thr Val Ser Ile Met Thr Cys Lys 
        195                 200                 205         


<210>  2909
<211>  254
<212>  PRT
<213>  homo sapiens

<400>  2909

Met Ala Ala Ala Ser Ala Gly Ala Thr Arg Leu Leu Leu Leu Leu Leu 
1               5                   10                  15      


Met Ala Val Ala Ala Pro Ser Arg Ala Arg Gly Ser Gly Cys Arg Ala 
            20                  25                  30          


Gly Thr Gly Ala Arg Gly Ala Gly Ala Glu Gly Arg Glu Gly Glu Ala 
        35                  40                  45              


Cys Gly Thr Val Gly Leu Leu Leu Glu His Ser Phe Glu Ile Asp Asp 
    50                  55                  60                  


Ser Ala Asn Phe Arg Lys Arg Gly Ser Leu Leu Trp Asn Gln Gln Asp 
65                  70                  75                  80  


Gly Thr Leu Ser Leu Ser Gln Arg Gln Leu Ser Glu Glu Glu Arg Gly 
                85                  90                  95      


Arg Leu Arg Asp Val Ala Ala Leu Asn Gly Leu Tyr Arg Val Arg Ile 
            100                 105                 110         


Pro Arg Arg Pro Gly Ala Leu Asp Gly Leu Glu Ala Gly Gly Tyr Val 
        115                 120                 125             


Ser Ser Phe Val Pro Ala Cys Ser Leu Val Glu Ser His Leu Ser Asp 
    130                 135                 140                 


Gln Leu Thr Leu His Val Asp Val Ala Gly Asn Val Val Gly Val Ser 
145                 150                 155                 160 


Val Val Thr His Pro Gly Gly Cys Arg Gly His Glu Val Glu Asp Val 
                165                 170                 175     


Asp Leu Glu Leu Phe Asn Thr Ser Val Gln Leu Gln Pro Pro Thr Thr 
            180                 185                 190         


Ala Pro Gly Pro Glu Thr Ala Ala Phe Ile Glu Arg Leu Glu Met Glu 
        195                 200                 205             


Gln Ala Gln Lys Ala Lys Asn Pro Gln Glu Gln Lys Ser Phe Phe Ala 
    210                 215                 220                 


Lys Tyr Trp His Ile Ile Leu Gly Gly Ala Val Leu Leu Thr Ala Leu 
225                 230                 235                 240 


Arg Pro Ala Ala Pro Gly Pro Ala Pro Pro Pro Gln Glu Ala 
                245                 250                 


<210>  2910
<211>  354
<212>  PRT
<213>  homo sapiens

<400>  2910

Met Thr Thr Ala Ile Leu Glu Arg Leu Ser Thr Leu Ser Val Ser Gly 
1               5                   10                  15      


Gln Gln Leu Arg Arg Leu Pro Lys Ile Leu Glu Asp Gly Leu Pro Lys 
            20                  25                  30          


Met Pro Cys Thr Val Pro Glu Thr Asp Val Pro Gln Leu Phe Arg Glu 
        35                  40                  45              


Pro Tyr Ile Arg Thr Gly Tyr Arg Pro Thr Gly His Glu Trp Arg Tyr 
    50                  55                  60                  


Tyr Phe Phe Ser Leu Phe Gln Lys His Asn Glu Val Val Asn Val Trp 
65                  70                  75                  80  


Thr His Leu Leu Ala Ala Leu Ala Val Leu Leu Arg Phe Trp Ala Phe 
                85                  90                  95      


Ala Glu Ala Glu Ala Leu Pro Trp Ala Ser Thr His Ser Leu Pro Leu 
            100                 105                 110         


Leu Leu Phe Ile Leu Ser Ser Ile Thr Tyr Leu Thr Cys Ser Leu Leu 
        115                 120                 125             


Ala His Leu Leu Gln Ser Lys Ser Glu Leu Ser His Tyr Thr Phe Tyr 
    130                 135                 140                 


Phe Val Asp Tyr Val Gly Val Ser Val Tyr Gln Tyr Gly Ser Ala Leu 
145                 150                 155                 160 


Ala His Phe Phe Tyr Ser Ser Asp Gln Ala Trp Tyr Asp Arg Phe Trp 
                165                 170                 175     


Leu Phe Phe Leu Pro Ala Ala Ala Phe Cys Gly Trp Leu Ser Cys Ala 
            180                 185                 190         


Gly Cys Cys Tyr Ala Lys Tyr Arg Tyr Arg Arg Pro Tyr Pro Val Met 
        195                 200                 205             


Arg Lys Ile Cys Gln Val Val Pro Ala Gly Leu Ala Phe Ile Leu Asp 
    210                 215                 220                 


Ile Ser Pro Val Ala His Arg Val Ala Leu Cys His Leu Ala Gly Cys 
225                 230                 235                 240 


Gln Glu Gln Ala Ala Trp Tyr His Thr Leu Gln Ile Leu Phe Phe Leu 
                245                 250                 255     


Val Ser Ala Tyr Phe Phe Ser Cys Pro Val Pro Glu Lys Tyr Phe Pro 
            260                 265                 270         


Gly Ser Cys Asp Ile Val Gly His Gly His Gln Ile Phe His Ala Phe 
        275                 280                 285             


Leu Ser Ile Cys Thr Leu Ser Gln Leu Glu Ala Ile Leu Leu Asp Tyr 
    290                 295                 300                 


Gln Gly Arg Gln Glu Ile Phe Leu Gln Arg His Gly Pro Leu Ser Val 
305                 310                 315                 320 


His Met Ala Cys Leu Ser Phe Phe Phe Leu Ala Ala Cys Ser Ala Ala 
                325                 330                 335     


Thr Ala Ala Leu Leu Arg His Lys Val Lys Ala Arg Leu Thr Lys Lys 
            340                 345                 350         


Asp Ser 
        


<210>  2911
<211>  1225
<212>  PRT
<213>  homo sapiens

<400>  2911

Met Phe Ala Arg Lys Pro Pro Gly Ala Ala Pro Leu Gly Ala Met Pro 
1               5                   10                  15      


Val Pro Asp Gln Pro Ser Ser Ala Ser Glu Lys Thr Ser Ser Leu Ser 
            20                  25                  30          


Pro Gly Leu Asn Thr Ser Asn Gly Asp Gly Ser Glu Thr Glu Thr Thr 
        35                  40                  45              


Ser Ala Ile Leu Ala Ser Val Lys Glu Gln Glu Leu Gln Phe Glu Arg 
    50                  55                  60                  


Leu Thr Arg Glu Leu Glu Ala Glu Arg Gln Ile Val Ala Ser Gln Leu 
65                  70                  75                  80  


Glu Arg Cys Lys Leu Gly Ser Glu Thr Gly Ser Met Ser Ser Met Ser 
                85                  90                  95      


Ser Ala Glu Glu Gln Phe Gln Trp Gln Ser Gln Asp Gly Gln Lys Asp 
            100                 105                 110         


Ile Glu Asp Glu Leu Thr Thr Gly Leu Glu Leu Val Asp Ser Cys Ile 
        115                 120                 125             


Arg Ser Leu Gln Glu Ser Gly Ile Leu Asp Pro Gln Asp Tyr Ser Thr 
    130                 135                 140                 


Gly Glu Arg Pro Ser Leu Leu Ser Gln Ser Ala Leu Gln Leu Asn Ser 
145                 150                 155                 160 


Lys Pro Glu Gly Ser Phe Gln Tyr Pro Ala Ser Tyr His Ser Asn Gln 
                165                 170                 175     


Thr Leu Ala Leu Gly Glu Thr Thr Pro Ser Gln Leu Pro Ala Arg Gly 
            180                 185                 190         


Thr Gln Ala Arg Ala Thr Gly Gln Ser Phe Ser Gln Gly Thr Thr Ser 
        195                 200                 205             


Arg Ala Gly His Leu Ala Gly Pro Glu Pro Ala Pro Pro Pro Pro Pro 
    210                 215                 220                 


Pro Pro Arg Glu Pro Phe Ala Pro Ser Leu Gly Ser Ala Phe His Leu 
225                 230                 235                 240 


Pro Asp Ala Pro Pro Ala Ala Ala Ala Ala Ala Leu Tyr Tyr Ser Ser 
                245                 250                 255     


Ser Thr Leu Pro Ala Pro Pro Arg Gly Gly Ser Pro Leu Ala Ala Pro 
            260                 265                 270         


Gln Gly Gly Ser Pro Thr Lys Leu Gln Arg Gly Gly Ser Ala Pro Glu 
        275                 280                 285             


Gly Ala Thr Tyr Ala Ala Pro Arg Gly Ser Ser Pro Lys Gln Ser Pro 
    290                 295                 300                 


Ser Arg Leu Ala Lys Ser Tyr Ser Thr Ser Ser Pro Ile Asn Ile Val 
305                 310                 315                 320 


Val Ser Ser Ala Gly Leu Ser Pro Ile Arg Val Thr Ser Pro Pro Thr 
                325                 330                 335     


Val Gln Ser Thr Ile Ser Ser Ser Pro Ile His Gln Leu Ser Ser Thr 
            340                 345                 350         


Ile Gly Thr Tyr Ala Thr Leu Ser Pro Thr Lys Arg Leu Val His Ala 
        355                 360                 365             


Ser Glu Gln Tyr Ser Lys His Ser Gln Glu Leu Tyr Ala Thr Ala Thr 
    370                 375                 380                 


Leu Gln Arg Pro Gly Ser Leu Ala Ala Gly Ser Arg Ala Ser Tyr Ser 
385                 390                 395                 400 


Ser Gln His Gly His Leu Gly Pro Glu Leu Arg Ala Leu Gln Ser Pro 
                405                 410                 415     


Glu His His Ile Asp Pro Ile Tyr Glu Asp Arg Val Tyr Gln Lys Pro 
            420                 425                 430         


Pro Met Arg Ser Leu Ser Gln Ser Gln Gly Asp Pro Leu Pro Pro Ala 
        435                 440                 445             


His Thr Gly Thr Tyr Arg Thr Ser Thr Ala Pro Ser Ser Pro Gly Val 
    450                 455                 460                 


Asp Ser Val Pro Leu Gln Arg Thr Gly Ser Gln His Gly Pro Gln Asn 
465                 470                 475                 480 


Ala Ala Ala Ala Thr Phe Gln Arg Ala Ser Tyr Ala Ala Gly Pro Ala 
                485                 490                 495     


Ser Asn Tyr Ala Asp Pro Tyr Arg Gln Leu Gln Tyr Cys Pro Ser Val 
            500                 505                 510         


Glu Ser Pro Tyr Ser Lys Ser Gly Pro Ala Leu Pro Pro Glu Gly Thr 
        515                 520                 525             


Leu Ala Arg Ser Pro Ser Ile Asp Ser Ile Gln Lys Asp Pro Arg Glu 
    530                 535                 540                 


Phe Gly Trp Arg Asp Pro Glu Leu Pro Glu Val Ile Gln Met Leu Gln 
545                 550                 555                 560 


His Gln Phe Pro Ser Val Gln Ser Asn Ala Ala Ala Tyr Leu Gln His 
                565                 570                 575     


Leu Cys Phe Gly Asp Asn Lys Ile Lys Ala Glu Ile Arg Arg Gln Gly 
            580                 585                 590         


Gly Ile Gln Leu Leu Val Asp Leu Leu Asp His Arg Met Thr Glu Val 
        595                 600                 605             


His Arg Ser Ala Cys Gly Ala Leu Arg Asn Leu Val Tyr Gly Lys Ala 
    610                 615                 620                 


Asn Asp Asp Asn Lys Ile Ala Leu Lys Asn Cys Gly Gly Ile Pro Ala 
625                 630                 635                 640 


Leu Val Arg Leu Leu Arg Lys Thr Thr Asp Leu Glu Ile Arg Glu Leu 
                645                 650                 655     


Val Thr Gly Val Leu Trp Asn Leu Ser Ser Cys Asp Ala Leu Lys Met 
            660                 665                 670         


Pro Ile Ile Gln Asp Ala Leu Ala Val Leu Thr Asn Ala Val Ile Ile 
        675                 680                 685             


Pro His Ser Gly Trp Glu Asn Ser Pro Leu Gln Asp Asp Arg Lys Ile 
    690                 695                 700                 


Gln Leu His Ser Ser Gln Val Leu Arg Asn Ala Thr Gly Cys Leu Arg 
705                 710                 715                 720 


Asn Val Ser Ser Ala Gly Glu Glu Ala Arg Arg Arg Met Arg Glu Cys 
                725                 730                 735     


Asp Gly Leu Thr Asp Ala Leu Leu Tyr Val Ile Gln Ser Ala Leu Gly 
            740                 745                 750         


Ser Ser Glu Ile Asp Ser Lys Thr Val Glu Asn Cys Val Cys Ile Leu 
        755                 760                 765             


Arg Asn Leu Ser Tyr Arg Leu Ala Ala Glu Thr Ser Gln Gly Gln His 
    770                 775                 780                 


Met Gly Thr Asp Glu Leu Asp Gly Leu Leu Cys Gly Glu Ala Asn Gly 
785                 790                 795                 800 


Lys Asp Ala Glu Ser Ser Gly Cys Trp Gly Lys Lys Lys Lys Lys Lys 
                805                 810                 815     


Lys Ser Gln Asp Gln Trp Asp Gly Val Gly Pro Leu Pro Asp Cys Ala 
            820                 825                 830         


Glu Pro Pro Lys Gly Ile Gln Met Leu Trp His Pro Ser Ile Val Lys 
        835                 840                 845             


Pro Tyr Leu Thr Leu Leu Ser Glu Cys Ser Asn Pro Asp Thr Leu Glu 
    850                 855                 860                 


Gly Ala Ala Gly Ala Leu Gln Asn Leu Ala Ala Gly Ser Trp Lys Trp 
865                 870                 875                 880 


Ser Val Tyr Ile Arg Ala Ala Val Arg Lys Glu Lys Gly Leu Pro Ile 
                885                 890                 895     


Leu Val Glu Leu Leu Arg Ile Asp Asn Asp Arg Val Val Cys Ala Val 
            900                 905                 910         


Ala Thr Ala Leu Arg Asn Met Ala Leu Asp Val Arg Asn Lys Glu Leu 
        915                 920                 925             


Ile Gly Lys Tyr Ala Met Arg Asp Leu Val His Arg Leu Pro Gly Gly 
    930                 935                 940                 


Asn Asn Ser Asn Asn Thr Ala Ser Lys Ala Met Ser Asp Asp Thr Val 
945                 950                 955                 960 


Thr Ala Val Cys Cys Thr Leu His Glu Val Ile Thr Lys Asn Met Glu 
                965                 970                 975     


Asn Ala Lys Ala Leu Arg Asp Ala Gly Gly Ile Glu Lys Leu Val Gly 
            980                 985                 990         


Ile Ser Lys Ser Lys Gly Asp Lys  His Ser Pro Lys Val  Val Lys Ala 
        995                 1000                 1005             


Ala Ser  Gln Val Leu Asn Ser  Met Trp Gln Tyr Arg  Asp Leu Arg 
    1010                 1015                 1020             


Ser Leu  Tyr Lys Lys Asp Gly  Trp Ser Gln Tyr His  Phe Val Ala 
    1025                 1030                 1035             


Ser Ser  Ser Thr Ile Glu Arg  Asp Arg Gln Arg Pro  Tyr Ser Ser 
    1040                 1045                 1050             


Ser Arg  Thr Pro Ser Ile Ser  Pro Val Arg Val Ser  Pro Asn Asn 
    1055                 1060                 1065             


Arg Ser  Ala Ser Ala Pro Ala  Ser Pro Arg Glu Met  Ile Ser Leu 
    1070                 1075                 1080             


Lys Glu  Arg Lys Thr Asp Tyr  Glu Cys Thr Gly Ser  Asn Ala Thr 
    1085                 1090                 1095             


Tyr His  Gly Ala Lys Gly Glu  His Thr Ser Arg Lys  Asp Ala Met 
    1100                 1105                 1110             


Thr Ala  Gln Asn Thr Gly Ile  Ser Thr Leu Tyr Arg  Asn Ser Tyr 
    1115                 1120                 1125             


Gly Ala  Pro Ala Glu Asp Ile  Lys His Asn Gln Val  Ser Ala Gln 
    1130                 1135                 1140             


Pro Val  Pro Gln Glu Pro Ser  Arg Lys Asp Tyr Glu  Thr Tyr Gln 
    1145                 1150                 1155             


Pro Phe  Gln Asn Ser Thr Arg  Asn Tyr Asp Glu Ser  Phe Phe Glu 
    1160                 1165                 1170             


Asp Gln  Val His His Arg Pro  Pro Ala Ser Glu Tyr  Thr Met His 
    1175                 1180                 1185             


Leu Gly  Leu Lys Ser Thr Gly  Asn Tyr Val Asp Phe  Tyr Ser Ala 
    1190                 1195                 1200             


Ala Arg  Pro Tyr Ser Glu Leu  Asn Tyr Glu Thr Ser  His Tyr Pro 
    1205                 1210                 1215             


Ala Ser  Pro Asp Ser Trp Val  
    1220                 1225 


<210>  2912
<211>  2912
<212>  PRT
<213>  homo sapiens

<400>  2912

Met Gly Arg Arg Arg Arg Leu Cys Leu Gln Leu Tyr Phe Leu Trp Leu 
1               5                   10                  15      


Gly Cys Val Val Leu Trp Ala Gln Gly Thr Ala Gly Gln Pro Gln Pro 
            20                  25                  30          


Pro Pro Pro Lys Pro Pro Arg Pro Gln Pro Pro Pro Gln Gln Val Arg 
        35                  40                  45              


Ser Ala Thr Ala Gly Ser Glu Gly Gly Phe Leu Ala Pro Glu Tyr Arg 
    50                  55                  60                  


Glu Glu Gly Ala Ala Val Ala Ser Arg Val Arg Arg Arg Gly Gln Gln 
65                  70                  75                  80  


Asp Val Leu Arg Gly Pro Asn Val Cys Gly Ser Arg Phe His Ser Tyr 
                85                  90                  95      


Cys Cys Pro Gly Trp Lys Thr Leu Pro Gly Gly Asn Gln Cys Ile Val 
            100                 105                 110         


Pro Ile Cys Arg Asn Ser Cys Gly Asp Gly Phe Cys Ser Arg Pro Asn 
        115                 120                 125             


Met Cys Thr Cys Ser Ser Gly Gln Ile Ser Ser Thr Cys Gly Ser Lys 
    130                 135                 140                 


Ser Ile Gln Gln Cys Ser Val Arg Cys Met Asn Gly Gly Thr Cys Ala 
145                 150                 155                 160 


Asp Asp His Cys Gln Cys Gln Lys Gly Tyr Ile Gly Thr Tyr Cys Gly 
                165                 170                 175     


Gln Pro Val Cys Glu Asn Gly Cys Gln Asn Gly Gly Arg Cys Ile Gly 
            180                 185                 190         


Pro Asn Arg Cys Ala Cys Val Tyr Gly Phe Thr Gly Pro Gln Cys Glu 
        195                 200                 205             


Arg Asp Tyr Arg Thr Gly Pro Cys Phe Thr Gln Val Asn Asn Gln Met 
    210                 215                 220                 


Cys Gln Gly Gln Leu Thr Gly Ile Val Cys Thr Lys Thr Leu Cys Cys 
225                 230                 235                 240 


Ala Thr Ile Gly Arg Ala Trp Gly His Pro Cys Glu Met Cys Pro Ala 
                245                 250                 255     


Gln Pro Gln Pro Cys Arg Arg Gly Phe Ile Pro Asn Ile Arg Thr Gly 
            260                 265                 270         


Ala Cys Gln Asp Val Asp Glu Cys Gln Ala Ile Pro Gly Ile Cys Gln 
        275                 280                 285             


Gly Gly Asn Cys Ile Asn Thr Val Gly Ser Phe Glu Cys Arg Cys Pro 
    290                 295                 300                 


Ala Gly His Lys Gln Ser Glu Thr Thr Gln Lys Cys Glu Asp Ile Asp 
305                 310                 315                 320 


Glu Cys Ser Ile Ile Pro Gly Ile Cys Glu Thr Gly Glu Cys Ser Asn 
                325                 330                 335     


Thr Val Gly Ser Tyr Phe Cys Val Cys Pro Arg Gly Tyr Val Thr Ser 
            340                 345                 350         


Thr Asp Gly Ser Arg Cys Ile Asp Gln Arg Thr Gly Met Cys Phe Ser 
        355                 360                 365             


Gly Leu Val Asn Gly Arg Cys Ala Gln Glu Leu Pro Gly Arg Met Thr 
    370                 375                 380                 


Lys Met Gln Cys Cys Cys Glu Pro Gly Arg Cys Trp Gly Ile Gly Thr 
385                 390                 395                 400 


Ile Pro Glu Ala Cys Pro Val Arg Gly Ser Glu Glu Tyr Arg Arg Leu 
                405                 410                 415     


Cys Met Asp Gly Leu Pro Met Gly Gly Ile Pro Gly Ser Ala Gly Ser 
            420                 425                 430         


Arg Pro Gly Gly Thr Gly Gly Asn Gly Phe Ala Pro Ser Gly Asn Gly 
        435                 440                 445             


Asn Gly Tyr Gly Pro Gly Gly Thr Gly Phe Ile Pro Ile Pro Gly Gly 
    450                 455                 460                 


Asn Gly Phe Ser Pro Gly Val Gly Gly Ala Gly Val Gly Ala Gly Gly 
465                 470                 475                 480 


Gln Gly Pro Ile Ile Thr Gly Leu Thr Ile Leu Asn Gln Thr Ile Asp 
                485                 490                 495     


Ile Cys Lys His His Ala Asn Leu Cys Leu Asn Gly Arg Cys Ile Pro 
            500                 505                 510         


Thr Val Ser Ser Tyr Arg Cys Glu Cys Asn Met Gly Tyr Lys Gln Asp 
        515                 520                 525             


Ala Asn Gly Asp Cys Ile Asp Val Asp Glu Cys Thr Ser Asn Pro Cys 
    530                 535                 540                 


Thr Asn Gly Asp Cys Val Asn Thr Pro Gly Ser Tyr Tyr Cys Lys Cys 
545                 550                 555                 560 


His Ala Gly Phe Gln Arg Thr Pro Thr Lys Gln Ala Cys Ile Asp Ile 
                565                 570                 575     


Asp Glu Cys Ile Gln Asn Gly Val Leu Cys Lys Asn Gly Arg Cys Val 
            580                 585                 590         


Asn Thr Asp Gly Ser Phe Gln Cys Ile Cys Asn Ala Gly Phe Glu Leu 
        595                 600                 605             


Thr Thr Asp Gly Lys Asn Cys Val Asp His Asp Glu Cys Thr Thr Thr 
    610                 615                 620                 


Asn Met Cys Leu Asn Gly Met Cys Ile Asn Glu Asp Gly Ser Phe Lys 
625                 630                 635                 640 


Cys Ile Cys Lys Pro Gly Phe Val Leu Ala Pro Asn Gly Arg Tyr Cys 
                645                 650                 655     


Thr Asp Val Asp Glu Cys Gln Thr Pro Gly Ile Cys Met Asn Gly His 
            660                 665                 670         


Cys Ile Asn Ser Glu Gly Ser Phe Arg Cys Asp Cys Pro Pro Gly Leu 
        675                 680                 685             


Ala Val Gly Met Asp Gly Arg Val Cys Val Asp Thr His Met Arg Ser 
    690                 695                 700                 


Thr Cys Tyr Gly Gly Ile Lys Lys Gly Val Cys Val Arg Pro Phe Pro 
705                 710                 715                 720 


Gly Ala Val Thr Lys Ser Glu Cys Cys Cys Ala Asn Pro Asp Tyr Gly 
                725                 730                 735     


Phe Gly Glu Pro Cys Gln Pro Cys Pro Ala Lys Asn Ser Ala Glu Phe 
            740                 745                 750         


His Gly Leu Cys Ser Ser Gly Val Gly Ile Thr Val Asp Gly Arg Asp 
        755                 760                 765             


Ile Asn Glu Cys Ala Leu Asp Pro Asp Ile Cys Ala Asn Gly Ile Cys 
    770                 775                 780                 


Glu Asn Leu Arg Gly Ser Tyr Arg Cys Asn Cys Asn Ser Gly Tyr Glu 
785                 790                 795                 800 


Pro Asp Ala Ser Gly Arg Asn Cys Ile Asp Ile Asp Glu Cys Leu Val 
                805                 810                 815     


Asn Arg Leu Leu Cys Asp Asn Gly Leu Cys Arg Asn Thr Pro Gly Ser 
            820                 825                 830         


Tyr Ser Cys Thr Cys Pro Pro Gly Tyr Val Phe Arg Thr Glu Thr Glu 
        835                 840                 845             


Thr Cys Glu Asp Ile Asn Glu Cys Glu Ser Asn Pro Cys Val Asn Gly 
    850                 855                 860                 


Ala Cys Arg Asn Asn Leu Gly Ser Phe Asn Cys Glu Cys Ser Pro Gly 
865                 870                 875                 880 


Ser Lys Leu Ser Ser Thr Gly Leu Ile Cys Ile Asp Ser Leu Lys Gly 
                885                 890                 895     


Thr Cys Trp Leu Asn Ile Gln Asp Ser Arg Cys Glu Val Asn Ile Asn 
            900                 905                 910         


Gly Ala Thr Leu Lys Ser Glu Cys Cys Ala Thr Leu Gly Ala Ala Trp 
        915                 920                 925             


Gly Ser Pro Cys Glu Arg Cys Glu Leu Asp Thr Ala Cys Pro Arg Gly 
    930                 935                 940                 


Leu Ala Arg Ile Lys Gly Val Thr Cys Glu Asp Val Asn Glu Cys Glu 
945                 950                 955                 960 


Val Phe Pro Gly Val Cys Pro Asn Gly Arg Cys Val Asn Ser Lys Gly 
                965                 970                 975     


Ser Phe His Cys Glu Cys Pro Glu Gly Leu Thr Leu Asp Gly Thr Gly 
            980                 985                 990         


Arg Val Cys Leu Asp Ile Arg Met  Glu Gln Cys Tyr Leu  Lys Trp Asp 
        995                 1000                 1005             


Glu Asp  Glu Cys Ile His Pro  Val Pro Gly Lys Phe  Arg Met Asp 
    1010                 1015                 1020             


Ala Cys  Cys Cys Ala Val Gly  Ala Ala Trp Gly Thr  Glu Cys Glu 
    1025                 1030                 1035             


Glu Cys  Pro Lys Pro Gly Thr  Lys Glu Tyr Glu Thr  Leu Cys Pro 
    1040                 1045                 1050             


Arg Gly  Ala Gly Phe Ala Asn  Arg Gly Asp Val Leu  Thr Gly Arg 
    1055                 1060                 1065             


Pro Phe  Tyr Lys Asp Ile Asn  Glu Cys Lys Ala Phe  Pro Gly Met 
    1070                 1075                 1080             


Cys Thr  Tyr Gly Lys Cys Arg  Asn Thr Ile Gly Ser  Phe Lys Cys 
    1085                 1090                 1095             


Arg Cys  Asn Ser Gly Phe Ala  Leu Asp Met Glu Glu  Arg Asn Cys 
    1100                 1105                 1110             


Thr Asp  Ile Asp Glu Cys Arg  Ile Ser Pro Asp Leu  Cys Gly Ser 
    1115                 1120                 1125             


Gly Ile  Cys Val Asn Thr Pro  Gly Ser Phe Glu Cys  Glu Cys Phe 
    1130                 1135                 1140             


Glu Gly  Tyr Glu Ser Gly Phe  Met Met Met Lys Asn  Cys Met Asp 
    1145                 1150                 1155             


Ile Asp  Glu Cys Glu Arg Asn  Pro Leu Leu Cys Arg  Gly Gly Thr 
    1160                 1165                 1170             


Cys Val  Asn Thr Glu Gly Ser  Phe Gln Cys Asp Cys  Pro Leu Gly 
    1175                 1180                 1185             


His Glu  Leu Ser Pro Ser Arg  Glu Asp Cys Val Asp  Ile Asn Glu 
    1190                 1195                 1200             


Cys Ser  Leu Ser Asp Asn Leu  Cys Arg Asn Gly Lys  Cys Val Asn 
    1205                 1210                 1215             


Met Ile  Gly Thr Tyr Gln Cys  Ser Cys Asn Pro Gly  Tyr Gln Ala 
    1220                 1225                 1230             


Thr Pro  Asp Arg Gln Gly Cys  Thr Asp Ile Asp Glu  Cys Met Ile 
    1235                 1240                 1245             


Met Asn  Gly Gly Cys Asp Thr  Gln Cys Thr Asn Ser  Glu Gly Ser 
    1250                 1255                 1260             


Tyr Glu  Cys Ser Cys Ser Glu  Gly Tyr Ala Leu Met  Pro Asp Gly 
    1265                 1270                 1275             


Arg Ser  Cys Ala Asp Ile Asp  Glu Cys Glu Asn Asn  Pro Asp Ile 
    1280                 1285                 1290             


Cys Asp  Gly Gly Gln Cys Thr  Asn Ile Pro Gly Glu  Tyr Arg Cys 
    1295                 1300                 1305             


Leu Cys  Tyr Asp Gly Phe Met  Ala Ser Met Asp Met  Lys Thr Cys 
    1310                 1315                 1320             


Ile Asp  Val Asn Glu Cys Asp  Leu Asn Ser Asn Ile  Cys Met Phe 
    1325                 1330                 1335             


Gly Glu  Cys Glu Asn Thr Lys  Gly Ser Phe Ile Cys  His Cys Gln 
    1340                 1345                 1350             


Leu Gly  Tyr Ser Val Lys Lys  Gly Thr Thr Gly Cys  Thr Asp Val 
    1355                 1360                 1365             


Asp Glu  Cys Glu Ile Gly Ala  His Asn Cys Asp Met  His Ala Ser 
    1370                 1375                 1380             


Cys Leu  Asn Ile Pro Gly Ser  Phe Lys Cys Ser Cys  Arg Glu Gly 
    1385                 1390                 1395             


Trp Ile  Gly Asn Gly Ile Lys  Cys Ile Asp Leu Asp  Glu Cys Ser 
    1400                 1405                 1410             


Asn Gly  Thr His Gln Cys Ser  Ile Asn Ala Gln Cys  Val Asn Thr 
    1415                 1420                 1425             


Pro Gly  Ser Tyr Arg Cys Ala  Cys Ser Glu Gly Phe  Thr Gly Asp 
    1430                 1435                 1440             


Gly Phe  Thr Cys Ser Asp Val  Asp Glu Cys Ala Glu  Asn Ile Asn 
    1445                 1450                 1455             


Leu Cys  Glu Asn Gly Gln Cys  Leu Asn Val Pro Gly  Ala Tyr Arg 
    1460                 1465                 1470             


Cys Glu  Cys Glu Met Gly Phe  Thr Pro Ala Ser Asp  Ser Arg Ser 
    1475                 1480                 1485             


Cys Gln  Asp Ile Asp Glu Cys  Ser Phe Gln Asn Ile  Cys Val Phe 
    1490                 1495                 1500             


Gly Thr  Cys Asn Asn Leu Pro  Gly Met Phe His Cys  Ile Cys Asp 
    1505                 1510                 1515             


Asp Gly  Tyr Glu Leu Asp Arg  Thr Gly Gly Asn Cys  Thr Asp Ile 
    1520                 1525                 1530             


Asp Glu  Cys Ala Asp Pro Ile  Asn Cys Val Asn Gly  Leu Cys Val 
    1535                 1540                 1545             


Asn Thr  Pro Gly Arg Tyr Glu  Cys Asn Cys Pro Pro  Asp Phe Gln 
    1550                 1555                 1560             


Leu Asn  Pro Thr Gly Val Gly  Cys Val Asp Asn Arg  Val Gly Asn 
    1565                 1570                 1575             


Cys Tyr  Leu Lys Phe Gly Pro  Arg Gly Asp Gly Ser  Leu Ser Cys 
    1580                 1585                 1590             


Asn Thr  Glu Ile Gly Val Gly  Val Ser Arg Ser Ser  Cys Cys Cys 
    1595                 1600                 1605             


Ser Leu  Gly Lys Ala Trp Gly  Asn Pro Cys Glu Thr  Cys Pro Pro 
    1610                 1615                 1620             


Val Asn  Ser Thr Glu Tyr Tyr  Thr Leu Cys Pro Gly  Gly Glu Gly 
    1625                 1630                 1635             


Phe Arg  Pro Asn Pro Ile Thr  Ile Ile Leu Glu Asp  Ile Asp Glu 
    1640                 1645                 1650             


Cys Gln  Glu Leu Pro Gly Leu  Cys Gln Gly Gly Asn  Cys Ile Asn 
    1655                 1660                 1665             


Thr Phe  Gly Ser Phe Gln Cys  Glu Cys Pro Gln Gly  Tyr Tyr Leu 
    1670                 1675                 1680             


Ser Glu  Asp Thr Arg Ile Cys  Glu Asp Ile Asp Glu  Cys Phe Ala 
    1685                 1690                 1695             


His Pro  Gly Val Cys Gly Pro  Gly Thr Cys Tyr Asn  Thr Leu Gly 
    1700                 1705                 1710             


Asn Tyr  Thr Cys Ile Cys Pro  Pro Glu Tyr Met Gln  Val Asn Gly 
    1715                 1720                 1725             


Gly His  Asn Cys Met Asp Met  Arg Lys Ser Phe Cys  Tyr Arg Ser 
    1730                 1735                 1740             


Tyr Asn  Gly Thr Thr Cys Glu  Asn Glu Leu Pro Phe  Asn Val Thr 
    1745                 1750                 1755             


Lys Arg  Met Cys Cys Cys Thr  Tyr Asn Val Gly Lys  Ala Trp Asn 
    1760                 1765                 1770             


Lys Pro  Cys Glu Pro Cys Pro  Thr Pro Gly Thr Ala  Asp Phe Lys 
    1775                 1780                 1785             


Thr Ile  Cys Gly Asn Ile Pro  Gly Phe Thr Phe Asp  Ile His Thr 
    1790                 1795                 1800             


Gly Lys  Ala Val Asp Ile Asp  Glu Cys Lys Glu Ile  Pro Gly Ile 
    1805                 1810                 1815             


Cys Ala  Asn Gly Val Cys Ile  Asn Gln Ile Gly Ser  Phe Arg Cys 
    1820                 1825                 1830             


Glu Cys  Pro Thr Gly Phe Ser  Tyr Asn Asp Leu Leu  Leu Val Cys 
    1835                 1840                 1845             


Glu Asp  Ile Asp Glu Cys Ser  Asn Gly Asp Asn Leu  Cys Gln Arg 
    1850                 1855                 1860             


Asn Ala  Asp Cys Ile Asn Ser  Pro Gly Ser Tyr Arg  Cys Glu Cys 
    1865                 1870                 1875             


Ala Ala  Gly Phe Lys Leu Ser  Pro Asn Gly Ala Cys  Val Asp Arg 
    1880                 1885                 1890             


Asn Glu  Cys Leu Glu Ile Pro  Asn Val Cys Ser His  Gly Leu Cys 
    1895                 1900                 1905             


Val Asp  Leu Gln Gly Ser Tyr  Gln Cys Ile Cys His  Asn Gly Phe 
    1910                 1915                 1920             


Lys Ala  Ser Gln Asp Gln Thr  Met Cys Met Asp Val  Asp Glu Cys 
    1925                 1930                 1935             


Glu Arg  His Pro Cys Gly Asn  Gly Thr Cys Lys Asn  Thr Val Gly 
    1940                 1945                 1950             


Ser Tyr  Asn Cys Leu Cys Tyr  Pro Gly Phe Glu Leu  Thr His Asn 
    1955                 1960                 1965             


Asn Asp  Cys Leu Asp Ile Asp  Glu Cys Ser Ser Phe  Phe Gly Gln 
    1970                 1975                 1980             


Val Cys  Arg Asn Gly Arg Cys  Phe Asn Glu Ile Gly  Ser Phe Lys 
    1985                 1990                 1995             


Cys Leu  Cys Asn Glu Gly Tyr  Glu Leu Thr Pro Asp  Gly Lys Asn 
    2000                 2005                 2010             


Cys Ile  Asp Thr Asn Glu Cys  Val Ala Leu Pro Gly  Ser Cys Ser 
    2015                 2020                 2025             


Pro Gly  Thr Cys Gln Asn Leu  Glu Gly Ser Phe Arg  Cys Ile Cys 
    2030                 2035                 2040             


Pro Pro  Gly Tyr Glu Val Lys  Ser Glu Asn Cys Ile  Asp Ile Asn 
    2045                 2050                 2055             


Glu Cys  Asp Glu Asp Pro Asn  Ile Cys Leu Phe Gly  Ser Cys Thr 
    2060                 2065                 2070             


Asn Thr  Pro Gly Gly Phe Gln  Cys Leu Cys Pro Pro  Gly Phe Val 
    2075                 2080                 2085             


Leu Ser  Asp Asn Gly Arg Arg  Cys Phe Asp Thr Arg  Gln Ser Phe 
    2090                 2095                 2100             


Cys Phe  Thr Asn Phe Glu Asn  Gly Lys Cys Ser Val  Pro Lys Ala 
    2105                 2110                 2115             


Phe Asn  Thr Thr Lys Ala Lys  Cys Cys Cys Ser Lys  Met Pro Gly 
    2120                 2125                 2130             


Glu Gly  Trp Gly Asp Pro Cys  Glu Leu Cys Pro Lys  Asp Asp Glu 
    2135                 2140                 2145             


Val Ala  Phe Gln Asp Leu Cys  Pro Tyr Gly His Gly  Thr Val Pro 
    2150                 2155                 2160             


Ser Leu  His Asp Thr Arg Glu  Asp Val Asn Glu Cys  Leu Glu Ser 
    2165                 2170                 2175             


Pro Gly  Ile Cys Ser Asn Gly  Gln Cys Ile Asn Thr  Asp Gly Ser 
    2180                 2185                 2190             


Phe Arg  Cys Glu Cys Pro Met  Gly Tyr Asn Leu Asp  Tyr Thr Gly 
    2195                 2200                 2205             


Val Arg  Cys Val Asp Thr Asp  Glu Cys Ser Ile Gly  Asn Pro Cys 
    2210                 2215                 2220             


Gly Asn  Gly Thr Cys Thr Asn  Val Ile Gly Ser Phe  Glu Cys Asn 
    2225                 2230                 2235             


Cys Asn  Glu Gly Phe Glu Pro  Gly Pro Met Met Asn  Cys Glu Asp 
    2240                 2245                 2250             


Ile Asn  Glu Cys Ala Gln Asn  Pro Leu Leu Cys Ala  Phe Arg Cys 
    2255                 2260                 2265             


Met Asn  Thr Phe Gly Ser Tyr  Glu Cys Thr Cys Pro  Ile Gly Tyr 
    2270                 2275                 2280             


Ala Leu  Arg Glu Asp Gln Lys  Met Cys Lys Asp Leu  Asp Glu Cys 
    2285                 2290                 2295             


Ala Glu  Gly Leu His Asp Cys  Glu Ser Arg Gly Met  Met Cys Lys 
    2300                 2305                 2310             


Asn Leu  Ile Gly Thr Phe Met  Cys Ile Cys Pro Pro  Gly Met Ala 
    2315                 2320                 2325             


Arg Arg  Pro Asp Gly Glu Gly  Cys Val Asp Glu Asn  Glu Cys Arg 
    2330                 2335                 2340             


Thr Lys  Pro Gly Ile Cys Glu  Asn Gly Arg Cys Val  Asn Ile Ile 
    2345                 2350                 2355             


Gly Ser  Tyr Arg Cys Glu Cys  Asn Glu Gly Phe Gln  Ser Ser Ser 
    2360                 2365                 2370             


Ser Gly  Thr Glu Cys Leu Asp  Asn Arg Gln Gly Leu  Cys Phe Ala 
    2375                 2380                 2385             


Glu Val  Leu Gln Thr Ile Cys  Gln Met Ala Ser Ser  Ser Arg Asn 
    2390                 2395                 2400             


Leu Val  Thr Lys Ser Glu Cys  Cys Cys Asp Gly Gly  Arg Gly Trp 
    2405                 2410                 2415             


Gly His  Gln Cys Glu Leu Cys  Pro Leu Pro Gly Thr  Ala Gln Tyr 
    2420                 2425                 2430             


Lys Lys  Ile Cys Pro His Gly  Pro Gly Tyr Thr Thr  Asp Gly Arg 
    2435                 2440                 2445             


Asp Ile  Asp Glu Cys Lys Val  Met Pro Asn Leu Cys  Thr Asn Gly 
    2450                 2455                 2460             


Gln Cys  Ile Asn Thr Met Gly  Ser Phe Arg Cys Phe  Cys Lys Val 
    2465                 2470                 2475             


Gly Tyr  Thr Thr Asp Ile Ser  Gly Thr Ser Cys Ile  Asp Leu Asp 
    2480                 2485                 2490             


Glu Cys  Ser Gln Ser Pro Lys  Pro Cys Asn Tyr Ile  Cys Lys Asn 
    2495                 2500                 2505             


Thr Glu  Gly Ser Tyr Gln Cys  Ser Cys Pro Arg Gly  Tyr Val Leu 
    2510                 2515                 2520             


Gln Glu  Asp Gly Lys Thr Cys  Lys Asp Leu Asp Glu  Cys Gln Thr 
    2525                 2530                 2535             


Lys Gln  His Asn Cys Gln Phe  Leu Cys Val Asn Thr  Leu Gly Gly 
    2540                 2545                 2550             


Phe Thr  Cys Lys Cys Pro Pro  Gly Phe Thr Gln His  His Thr Ala 
    2555                 2560                 2565             


Cys Ile  Asp Asn Asn Glu Cys  Gly Ser Gln Pro Ser  Leu Cys Gly 
    2570                 2575                 2580             


Ala Lys  Gly Ile Cys Gln Asn  Thr Pro Gly Ser Phe  Ser Cys Glu 
    2585                 2590                 2595             


Cys Gln  Arg Gly Phe Ser Leu  Asp Ala Thr Gly Leu  Asn Cys Glu 
    2600                 2605                 2610             


Asp Val  Asp Glu Cys Asp Gly  Asn His Arg Cys Gln  His Gly Cys 
    2615                 2620                 2625             


Gln Asn  Ile Leu Gly Gly Tyr  Arg Cys Gly Cys Pro  Gln Gly Tyr 
    2630                 2635                 2640             


Ile Gln  His Tyr Gln Trp Asn  Gln Cys Val Asp Glu  Asn Glu Cys 
    2645                 2650                 2655             


Ser Asn  Pro Asn Ala Cys Gly  Ser Ala Ser Cys Tyr  Asn Thr Leu 
    2660                 2665                 2670             


Gly Ser  Tyr Lys Cys Ala Cys  Pro Ser Gly Phe Ser  Phe Asp Gln 
    2675                 2680                 2685             


Phe Ser  Ser Ala Cys His Asp  Val Asn Glu Cys Ser  Ser Ser Lys 
    2690                 2695                 2700             


Asn Pro  Cys Asn Tyr Gly Cys  Ser Asn Thr Glu Gly  Gly Tyr Leu 
    2705                 2710                 2715             


Cys Gly  Cys Pro Pro Gly Tyr  Tyr Arg Val Gly Gln  Gly His Cys 
    2720                 2725                 2730             


Val Ser  Gly Met Gly Phe Asn  Lys Gly Gln Tyr Leu  Ser Leu Asp 
    2735                 2740                 2745             


Thr Glu  Val Asp Glu Glu Asn  Ala Leu Ser Pro Glu  Ala Cys Tyr 
    2750                 2755                 2760             


Glu Cys  Lys Ile Asn Gly Tyr  Ser Lys Lys Asp Ser  Arg Gln Lys 
    2765                 2770                 2775             


Arg Ser  Ile His Glu Pro Asp  Pro Thr Ala Val Glu  Gln Ile Ser 
    2780                 2785                 2790             


Leu Glu  Ser Val Asp Met Asp  Ser Pro Val Asn Met  Lys Phe Asn 
    2795                 2800                 2805             


Leu Ser  His Leu Gly Ser Lys  Glu His Ile Leu Glu  Leu Arg Pro 
    2810                 2815                 2820             


Ala Ile  Gln Pro Leu Asn Asn  His Ile Arg Tyr Val  Ile Ser Gln 
    2825                 2830                 2835             


Gly Asn  Asp Asp Ser Val Phe  Arg Ile His Gln Arg  Asn Gly Leu 
    2840                 2845                 2850             


Ser Tyr  Leu His Thr Ala Lys  Lys Lys Leu Met Pro  Gly Thr Tyr 
    2855                 2860                 2865             


Thr Leu  Glu Ile Thr Ser Ile  Pro Leu Tyr Lys Lys  Lys Glu Leu 
    2870                 2875                 2880             


Lys Lys  Leu Glu Glu Ser Asn  Glu Asp Asp Tyr Leu  Leu Gly Glu 
    2885                 2890                 2895             


Leu Gly  Glu Ala Leu Arg Met  Arg Leu Gln Ile Gln  Leu Tyr 
    2900                 2905                 2910         


<210>  2913
<211>  465
<212>  PRT
<213>  homo sapiens

<400>  2913

Met Phe Leu Ala Thr Leu Tyr Phe Ala Leu Pro Leu Leu Asp Leu Leu 
1               5                   10                  15      


Leu Ser Ala Glu Val Ser Gly Gly Asp Arg Leu Asp Cys Val Lys Ala 
            20                  25                  30          


Ser Asp Gln Cys Leu Lys Glu Gln Ser Cys Ser Thr Lys Tyr Arg Thr 
        35                  40                  45              


Leu Arg Gln Cys Val Ala Gly Lys Glu Thr Asn Phe Ser Leu Ala Ser 
    50                  55                  60                  


Gly Leu Glu Ala Lys Asp Glu Cys Arg Ser Ala Met Glu Ala Leu Lys 
65                  70                  75                  80  


Gln Lys Ser Leu Tyr Asn Cys Arg Cys Lys Arg Gly Met Lys Lys Glu 
                85                  90                  95      


Lys Asn Cys Leu Arg Ile Tyr Trp Ser Met Tyr Gln Ser Leu Gln Gly 
            100                 105                 110         


Asn Asp Leu Leu Glu Asp Ser Pro Tyr Glu Pro Val Asn Ser Arg Leu 
        115                 120                 125             


Ser Asp Ile Phe Arg Val Val Pro Phe Ile Ser Asp Val Phe Gln Gln 
    130                 135                 140                 


Val Glu His Ile Pro Lys Gly Asn Asn Cys Leu Asp Ala Ala Lys Ala 
145                 150                 155                 160 


Cys Asn Leu Asp Asp Ile Cys Lys Lys Tyr Arg Ser Ala Tyr Ile Thr 
                165                 170                 175     


Pro Cys Thr Thr Ser Val Ser Asn Asp Val Cys Asn Arg Arg Lys Cys 
            180                 185                 190         


His Lys Ala Leu Arg Gln Phe Phe Asp Lys Val Pro Ala Lys His Ser 
        195                 200                 205             


Tyr Gly Met Leu Phe Cys Ser Cys Arg Asp Ile Ala Cys Thr Glu Arg 
    210                 215                 220                 


Arg Arg Gln Thr Ile Val Pro Val Cys Ser Tyr Glu Glu Arg Glu Lys 
225                 230                 235                 240 


Pro Asn Cys Leu Asn Leu Gln Asp Ser Cys Lys Thr Asn Tyr Ile Cys 
                245                 250                 255     


Arg Ser Arg Leu Ala Asp Phe Phe Thr Asn Cys Gln Pro Glu Ser Arg 
            260                 265                 270         


Ser Val Ser Ser Cys Leu Lys Glu Asn Tyr Ala Asp Cys Leu Leu Ala 
        275                 280                 285             


Tyr Ser Gly Leu Ile Gly Thr Val Met Thr Pro Asn Tyr Ile Asp Ser 
    290                 295                 300                 


Ser Ser Leu Ser Val Ala Pro Trp Cys Asp Cys Ser Asn Ser Gly Asn 
305                 310                 315                 320 


Asp Leu Glu Glu Cys Leu Lys Phe Leu Asn Phe Phe Lys Asp Asn Thr 
                325                 330                 335     


Cys Leu Lys Asn Ala Ile Gln Ala Phe Gly Asn Gly Ser Asp Val Thr 
            340                 345                 350         


Val Trp Gln Pro Ala Phe Pro Val Gln Thr Thr Thr Ala Thr Thr Thr 
        355                 360                 365             


Thr Ala Leu Arg Val Lys Asn Lys Pro Leu Gly Pro Ala Gly Ser Glu 
    370                 375                 380                 


Asn Glu Ile Pro Thr His Val Leu Pro Pro Cys Ala Asn Leu Gln Ala 
385                 390                 395                 400 


Gln Lys Leu Lys Ser Asn Val Ser Gly Asn Thr His Leu Cys Ile Ser 
                405                 410                 415     


Asn Gly Asn Tyr Glu Lys Glu Gly Leu Gly Ala Ser Ser His Ile Thr 
            420                 425                 430         


Thr Lys Ser Met Ala Ala Pro Pro Ser Cys Gly Leu Ser Pro Leu Leu 
        435                 440                 445             


Val Leu Val Val Thr Ala Leu Ser Thr Leu Leu Ser Leu Thr Glu Thr 
    450                 455                 460                 


Ser 
465 


<210>  2914
<211>  1505
<212>  PRT
<213>  homo sapiens

<400>  2914

Met Leu Cys Val Ala Gly Ala Arg Leu Lys Arg Glu Leu Asp Ala Thr 
1               5                   10                  15      


Ala Thr Val Leu Ala Asn Arg Gln Asp Glu Ser Glu Gln Ser Arg Lys 
            20                  25                  30          


Arg Leu Ile Glu Gln Ser Arg Glu Phe Lys Lys Asn Thr Pro Glu Asp 
        35                  40                  45              


Leu Arg Lys Gln Val Ala Pro Leu Leu Lys Ser Phe Gln Gly Glu Ile 
    50                  55                  60                  


Asp Ala Leu Ser Lys Arg Ser Lys Glu Ala Glu Ala Ala Phe Leu Asn 
65                  70                  75                  80  


Val Tyr Lys Arg Leu Ile Asp Val Pro Asp Pro Val Pro Ala Leu Asp 
                85                  90                  95      


Leu Gly Gln Gln Leu Gln Leu Lys Val Gln Arg Leu His Asp Ile Glu 
            100                 105                 110         


Thr Glu Asn Gln Lys Leu Arg Glu Thr Leu Glu Glu Tyr Asn Lys Glu 
        115                 120                 125             


Phe Ala Glu Val Lys Asn Gln Glu Val Thr Ile Lys Ala Leu Lys Glu 
    130                 135                 140                 


Lys Ile Arg Glu Tyr Glu Gln Thr Leu Lys Asn Gln Ala Glu Thr Ile 
145                 150                 155                 160 


Ala Leu Glu Lys Glu Gln Lys Leu Gln Asn Asp Phe Ala Glu Lys Glu 
                165                 170                 175     


Arg Lys Leu Gln Glu Thr Gln Met Ser Thr Thr Ser Lys Leu Glu Glu 
            180                 185                 190         


Ala Glu His Lys Val Gln Ser Leu Gln Thr Ala Leu Glu Lys Thr Arg 
        195                 200                 205             


Thr Glu Leu Phe Asp Leu Lys Thr Lys Tyr Asp Glu Glu Thr Thr Ala 
    210                 215                 220                 


Lys Ala Asp Glu Ile Glu Met Ile Met Thr Asp Leu Glu Arg Ala Asn 
225                 230                 235                 240 


Gln Arg Ala Glu Val Ala Gln Arg Glu Ala Glu Thr Leu Arg Glu Gln 
                245                 250                 255     


Leu Ser Ser Ala Asn His Ser Leu Gln Leu Ala Ser Gln Ile Gln Lys 
            260                 265                 270         


Ala Pro Asp Val Glu Gln Ala Ile Glu Val Leu Thr Arg Ser Ser Leu 
        275                 280                 285             


Glu Val Glu Leu Ala Ala Lys Glu Arg Glu Ile Ala Gln Leu Val Glu 
    290                 295                 300                 


Asp Val Gln Arg Leu Gln Ala Ser Leu Thr Lys Leu Arg Glu Asn Ser 
305                 310                 315                 320 


Ala Ser Gln Ile Ser Gln Leu Glu Gln Gln Leu Ser Ala Lys Asn Ser 
                325                 330                 335     


Thr Leu Lys Gln Leu Glu Glu Lys Leu Lys Gly Gln Ala Asp Tyr Glu 
            340                 345                 350         


Glu Val Lys Lys Glu Leu Asn Ile Leu Lys Ser Met Glu Phe Ala Pro 
        355                 360                 365             


Ser Glu Gly Ala Gly Thr Gln Asp Ala Ala Lys Pro Leu Glu Val Leu 
    370                 375                 380                 


Leu Leu Glu Lys Asn Arg Ser Leu Gln Ser Glu Asn Ala Ala Leu Arg 
385                 390                 395                 400 


Ile Ser Asn Ser Asp Leu Ser Gly Ser Ala Arg Arg Lys Gly Lys Asp 
                405                 410                 415     


Gln Pro Glu Ser Arg Arg Pro Gly Ser Leu Pro Ala Pro Pro Pro Ser 
            420                 425                 430         


Gln Leu Pro Arg Asn Pro Gly Glu Gln Ala Ser Asn Thr Asn Gly Thr 
        435                 440                 445             


His Gln Phe Ser Pro Ala Gly Leu Ser Gln Asp Phe Phe Ser Ser Ser 
    450                 455                 460                 


Leu Ala Ser Pro Ser Leu Pro Leu Ala Ser Thr Gly Lys Phe Ala Leu 
465                 470                 475                 480 


Asn Ser Leu Leu Gln Arg Gln Leu Met Gln Ser Phe Tyr Ser Lys Ala 
                485                 490                 495     


Met Gln Glu Ala Gly Ser Thr Ser Met Ile Phe Ser Thr Gly Pro Tyr 
            500                 505                 510         


Ser Thr Asn Ser Ile Ser Ser Gln Ser Pro Leu Gln Gln Ser Pro Asp 
        515                 520                 525             


Val Asn Gly Met Ala Pro Ser Pro Ser Gln Ser Glu Ser Ala Gly Ser 
    530                 535                 540                 


Val Ser Glu Gly Glu Glu Met Asp Thr Ala Glu Ile Ala Arg Gln Val 
545                 550                 555                 560 


Lys Glu Gln Leu Ile Lys His Asn Ile Gly Gln Arg Ile Phe Gly His 
                565                 570                 575     


Tyr Val Leu Gly Leu Ser Gln Gly Ser Val Ser Glu Ile Leu Ala Arg 
            580                 585                 590         


Pro Lys Pro Trp Asn Lys Leu Thr Val Arg Gly Lys Glu Pro Phe His 
        595                 600                 605             


Lys Met Lys Gln Phe Leu Ser Asp Glu Gln Asn Ile Leu Ala Leu Arg 
    610                 615                 620                 


Ser Ile Gln Gly Arg Gln Arg Glu Asn Pro Gly Gln Ser Leu Asn Arg 
625                 630                 635                 640 


Leu Phe Gln Glu Val Pro Lys Arg Arg Asn Gly Ser Glu Gly Asn Ile 
                645                 650                 655     


Thr Thr Arg Ile Arg Ala Ser Glu Thr Gly Ser Asp Glu Ala Ile Lys 
            660                 665                 670         


Ser Ile Leu Glu Gln Ala Lys Arg Glu Leu Gln Val Gln Lys Thr Ala 
        675                 680                 685             


Glu Pro Ala Gln Pro Ser Ser Ala Ser Gly Ser Gly Asn Ser Asp Asp 
    690                 695                 700                 


Ala Ile Arg Ser Ile Leu Gln Gln Ala Arg Arg Glu Met Glu Ala Gln 
705                 710                 715                 720 


Gln Ala Ala Leu Asp Pro Ala Leu Lys Gln Ala Pro Leu Ser Gln Ser 
                725                 730                 735     


Asp Ile Thr Ile Leu Thr Pro Lys Leu Leu Ser Thr Ser Pro Met Pro 
            740                 745                 750         


Thr Val Ser Ser Tyr Pro Pro Leu Ala Ile Ser Leu Lys Lys Pro Ser 
        755                 760                 765             


Ala Ala Pro Glu Ala Gly Ala Ser Ala Leu Pro Asn Pro Pro Ala Leu 
    770                 775                 780                 


Lys Lys Glu Ala Gln Asp Ala Pro Gly Leu Asp Pro Gln Gly Ala Ala 
785                 790                 795                 800 


Asp Cys Ala Gln Gly Val Leu Arg Gln Val Lys Asn Glu Val Gly Arg 
                805                 810                 815     


Ser Gly Ala Trp Lys Asp His Trp Trp Ser Ala Val Gln Pro Glu Arg 
            820                 825                 830         


Arg Asn Ala Ala Ser Ser Glu Glu Ala Lys Ala Glu Glu Thr Gly Gly 
        835                 840                 845             


Gly Lys Glu Lys Gly Ser Gly Gly Ser Gly Gly Gly Ser Gln Pro Arg 
    850                 855                 860                 


Ala Glu Arg Ser Gln Leu Gln Gly Pro Ser Ser Ser Glu Tyr Trp Lys 
865                 870                 875                 880 


Glu Trp Pro Ser Ala Glu Ser Pro Tyr Ser Gln Ser Ser Glu Leu Ser 
                885                 890                 895     


Leu Thr Gly Ala Ser Arg Ser Glu Thr Pro Gln Asn Ser Pro Leu Pro 
            900                 905                 910         


Ser Ser Pro Ile Val Pro Met Ser Lys Pro Thr Lys Pro Ser Val Pro 
        915                 920                 925             


Pro Leu Thr Pro Glu Gln Tyr Glu Val Tyr Met Tyr Gln Glu Val Asp 
    930                 935                 940                 


Thr Ile Glu Leu Thr Arg Gln Val Lys Glu Lys Leu Ala Lys Asn Gly 
945                 950                 955                 960 


Ile Cys Gln Arg Ile Phe Gly Glu Lys Val Leu Gly Leu Ser Gln Gly 
                965                 970                 975     


Ser Val Ser Asp Met Leu Ser Arg Pro Lys Pro Trp Ser Lys Leu Thr 
            980                 985                 990         


Gln Lys Gly Arg Glu Pro Phe Ile  Arg Met Gln Leu Trp  Leu Asn Gly 
        995                 1000                 1005             


Glu Leu  Gly Gln Gly Val Leu  Pro Val Gln Gly Gln  Gln Gln Gly 
    1010                 1015                 1020             


Pro Val  Leu His Ser Val Thr  Ser Leu Gln Asp Pro  Leu Gln Gln 
    1025                 1030                 1035             


Gly Cys  Val Ser Ser Glu Ser  Thr Pro Lys Thr Ser  Ala Ser Cys 
    1040                 1045                 1050             


Ser Pro  Ala Pro Glu Ser Pro  Met Ser Ser Ser Glu  Ser Val Lys 
    1055                 1060                 1065             


Ser Leu  Thr Glu Leu Val Gln  Gln Pro Cys Pro Pro  Ile Glu Ala 
    1070                 1075                 1080             


Ser Lys  Asp Ser Lys Pro Pro  Glu Pro Ser Asp Pro  Pro Ala Ser 
    1085                 1090                 1095             


Asp Ser  Gln Pro Thr Thr Pro  Leu Pro Leu Ser Gly  His Ser Ala 
    1100                 1105                 1110             


Leu Ser  Ile Gln Glu Leu Val  Ala Met Ser Pro Glu  Leu Asp Thr 
    1115                 1120                 1125             


Tyr Gly  Ile Thr Lys Arg Val  Lys Glu Val Leu Thr  Asp Asn Asn 
    1130                 1135                 1140             


Leu Gly  Gln Arg Leu Phe Gly  Glu Thr Ile Leu Gly  Leu Thr Gln 
    1145                 1150                 1155             


Gly Ser  Val Ser Asp Leu Leu  Ala Arg Pro Lys Pro  Trp His Lys 
    1160                 1165                 1170             


Leu Ser  Leu Lys Gly Arg Glu  Pro Phe Val Arg Met  Gln Leu Trp 
    1175                 1180                 1185             


Leu Asn  Asp Pro Asn Asn Val  Glu Lys Leu Met Asp  Met Lys Arg 
    1190                 1195                 1200             


Met Glu  Lys Lys Ala Tyr Met  Lys Arg Arg His Ser  Ser Val Ser 
    1205                 1210                 1215             


Asp Ser  Gln Pro Cys Glu Pro  Pro Ser Val Gly Thr  Glu Tyr Ser 
    1220                 1225                 1230             


Gln Gly  Ala Ser Pro Gln Pro  Gln His Gln Leu Lys  Lys Pro Arg 
    1235                 1240                 1245             


Val Val  Leu Ala Pro Glu Glu  Lys Glu Ala Leu Lys  Arg Ala Tyr 
    1250                 1255                 1260             


Gln Gln  Lys Pro Tyr Pro Ser  Pro Lys Thr Ile Glu  Asp Leu Ala 
    1265                 1270                 1275             


Thr Gln  Leu Asn Leu Lys Thr  Ser Thr Val Ile Asn  Trp Phe His 
    1280                 1285                 1290             


Asn Tyr  Arg Ser Arg Ile Arg  Arg Glu Leu Phe Ile  Glu Glu Ile 
    1295                 1300                 1305             


Gln Ala  Gly Ser Gln Gly Gln  Ala Gly Ala Ser Asp  Ser Pro Ser 
    1310                 1315                 1320             


Ala Arg  Ser Gly Arg Ala Ala  Pro Ser Ser Glu Gly  Asp Ser Cys 
    1325                 1330                 1335             


Asp Gly  Val Glu Ala Thr Glu  Gly Pro Gly Ser Ala  Asp Thr Glu 
    1340                 1345                 1350             


Glu Pro  Lys Ser Gln Gly Glu  Ala Glu Arg Glu Glu  Val Pro Arg 
    1355                 1360                 1365             


Pro Ala  Glu Gln Thr Glu Pro  Pro Pro Ser Gly Thr  Pro Gly Pro 
    1370                 1375                 1380             


Asp Asp  Ala Arg Asp Asp Asp  His Glu Gly Gly Pro  Val Glu Gly 
    1385                 1390                 1395             


Pro Gly  Pro Leu Pro Ser Pro  Ala Ser Ala Thr Ala  Thr Ala Ala 
    1400                 1405                 1410             


Pro Ala  Ala Pro Glu Asp Ala  Ala Thr Ser Ala Ala  Ala Ala Pro 
    1415                 1420                 1425             


Gly Glu  Gly Pro Ala Ala Pro  Ser Ser Ala Pro Pro  Pro Ser Asn 
    1430                 1435                 1440             


Ser Ser  Ser Ser Ser Ala Pro  Arg Arg Pro Ser Ser  Leu Gln Ser 
    1445                 1450                 1455             


Leu Phe  Gly Leu Pro Glu Ala  Ala Gly Ala Arg Asp  Ser Arg Asp 
    1460                 1465                 1470             


Asn Pro  Leu Arg Lys Lys Lys  Ala Ala Asn Leu Asn  Ser Ile Ile 
    1475                 1480                 1485             


His Arg  Leu Glu Lys Ala Ala  Ser Arg Glu Glu Pro  Ile Glu Trp 
    1490                 1495                 1500             


Glu Phe  
    1505 


<210>  2915
<211>  547
<212>  PRT
<213>  homo sapiens

<400>  2915

Met Phe Tyr Tyr Pro Asn Val Leu Gln Arg His Thr Gly Cys Phe Ala 
1               5                   10                  15      


Thr Ile Trp Leu Ala Ala Thr Arg Gly Ser Arg Leu Val Lys Arg Glu 
            20                  25                  30          


Tyr Leu Arg Val Asn Val Val Lys Thr Cys Glu Glu Ile Leu Asn Tyr 
        35                  40                  45              


Val Leu Val Arg Val Gln Pro Pro Gln Pro Gly Leu Pro Arg Pro Arg 
    50                  55                  60                  


Phe Ser Leu Tyr Leu Ser Ala Gln Leu Gln Ile Gly Val Ile Arg Val 
65                  70                  75                  80  


Tyr Ser Gln Gln Cys Gln Tyr Leu Val Glu Asp Ile Gln His Ile Leu 
                85                  90                  95      


Glu Arg Leu His Arg Ala Gln Leu Gln Ile Arg Ile Asp Met Glu Thr 
            100                 105                 110         


Glu Leu Pro Ser Leu Leu Leu Pro Asn His Leu Ala Met Met Glu Thr 
        115                 120                 125             


Leu Glu Asp Ala Pro Asp Pro Phe Phe Gly Met Met Ser Val Asp Pro 
    130                 135                 140                 


Arg Leu Pro Ser Pro Phe Asp Ile Pro Gln Ile Arg His Leu Leu Glu 
145                 150                 155                 160 


Ala Ala Ile Pro Glu Arg Val Glu Glu Ile Pro Pro Glu Val Pro Thr 
                165                 170                 175     


Glu Pro Arg Glu Pro Glu Arg Ile Pro Val Thr Val Leu Pro Pro Glu 
            180                 185                 190         


Ala Ile Thr Ile Leu Glu Ala Glu Pro Ile Arg Met Leu Glu Ile Glu 
        195                 200                 205             


Gly Glu Arg Glu Leu Pro Glu Val Ser Arg Arg Glu Leu Asp Leu Leu 
    210                 215                 220                 


Ile Ala Glu Glu Glu Glu Ala Ile Leu Leu Glu Ile Pro Arg Leu Pro 
225                 230                 235                 240 


Pro Pro Ala Pro Ala Glu Val Glu Gly Ile Gly Glu Ala Leu Gly Pro 
                245                 250                 255     


Glu Glu Leu Arg Leu Thr Gly Trp Glu Pro Gly Ala Leu Leu Met Glu 
            260                 265                 270         


Val Thr Pro Pro Glu Glu Leu Arg Leu Pro Ala Pro Pro Ser Pro Glu 
        275                 280                 285             


Arg Arg Pro Pro Val Pro Pro Pro Pro Arg Arg Arg Arg Arg Arg Arg 
    290                 295                 300                 


Leu Leu Phe Trp Asp Lys Glu Thr Gln Ile Ser Pro Glu Lys Phe Gln 
305                 310                 315                 320 


Glu Gln Leu Gln Thr Arg Ala His Cys Trp Glu Cys Pro Met Val Gln 
                325                 330                 335     


Pro Pro Glu Arg Thr Ile Arg Gly Pro Ala Glu Leu Phe Arg Thr Pro 
            340                 345                 350         


Thr Leu Ser Gly Trp Leu Pro Pro Glu Leu Leu Gly Leu Trp Thr His 
        355                 360                 365             


Cys Ala Gln Pro Pro Pro Lys Ala Leu Arg Arg Glu Leu Pro Glu Glu 
    370                 375                 380                 


Ala Ala Ala Glu Glu Glu Arg Arg Lys Ile Glu Val Pro Ser Glu Ile 
385                 390                 395                 400 


Glu Val Pro Arg Glu Ala Leu Glu Pro Ser Val Pro Leu Met Val Ser 
                405                 410                 415     


Leu Glu Ile Ser Leu Glu Ala Ala Glu Glu Glu Lys Ser Arg Ile Ser 
            420                 425                 430         


Leu Ile Pro Pro Glu Glu Arg Trp Ala Trp Pro Glu Val Glu Ala Pro 
        435                 440                 445             


Glu Ala Pro Ala Leu Pro Val Val Pro Glu Leu Pro Glu Val Pro Met 
    450                 455                 460                 


Glu Met Pro Leu Val Leu Pro Pro Glu Leu Glu Leu Leu Ser Leu Glu 
465                 470                 475                 480 


Ala Val His Arg Ala Val Ala Leu Glu Leu Gln Ala Asn Arg Glu Pro 
                485                 490                 495     


Asp Phe Ser Ser Leu Val Ser Pro Leu Ser Pro Arg Arg Met Ala Ala 
            500                 505                 510         


Arg Val Phe Tyr Leu Leu Leu Val Leu Ser Ala Gln Gln Ile Leu His 
        515                 520                 525             


Val Lys Gln Glu Lys Pro Tyr Gly Arg Leu Leu Ile Gln Pro Gly Pro 
    530                 535                 540                 


Arg Phe His 
545         


<210>  2916
<211>  649
<212>  PRT
<213>  homo sapiens

<400>  2916

Met Ala Ser Val Ser Ala Leu Thr Glu Glu Leu Asp Ser Ile Thr Ser 
1               5                   10                  15      


Glu Leu His Ala Val Glu Ile Gln Ile Gln Glu Leu Thr Glu Arg Gln 
            20                  25                  30          


Gln Glu Leu Ile Gln Lys Lys Lys Val Leu Thr Lys Lys Ile Lys Gln 
        35                  40                  45              


Cys Leu Glu Asp Ser Asp Ala Gly Ala Ser Asn Glu Tyr Asp Ser Ser 
    50                  55                  60                  


Pro Ala Ala Trp Asn Lys Glu Asp Phe Pro Trp Ser Gly Lys Val Lys 
65                  70                  75                  80  


Asp Ile Leu Gln Asn Val Phe Lys Leu Glu Lys Phe Arg Pro Leu Gln 
                85                  90                  95      


Leu Glu Thr Ile Asn Val Thr Met Ala Gly Lys Glu Val Phe Leu Val 
            100                 105                 110         


Met Pro Thr Gly Gly Gly Lys Ser Leu Cys Tyr Gln Leu Pro Ala Leu 
        115                 120                 125             


Cys Ser Asp Gly Phe Thr Leu Val Ile Cys Pro Leu Ile Ser Leu Met 
    130                 135                 140                 


Glu Asp Gln Leu Met Val Leu Lys Gln Leu Gly Ile Ser Ala Thr Met 
145                 150                 155                 160 


Leu Asn Ala Ser Ser Ser Lys Glu His Val Lys Trp Val His Ala Glu 
                165                 170                 175     


Met Val Asn Lys Asn Ser Glu Leu Lys Leu Ile Tyr Val Thr Pro Glu 
            180                 185                 190         


Lys Ile Ala Lys Ser Lys Met Phe Met Ser Arg Leu Glu Lys Ala Tyr 
        195                 200                 205             


Glu Ala Arg Arg Phe Thr Arg Ile Ala Val Asp Glu Val His Cys Cys 
    210                 215                 220                 


Ser Gln Trp Gly His Asp Phe Arg Pro Asp Tyr Lys Ala Leu Gly Ile 
225                 230                 235                 240 


Leu Lys Arg Gln Phe Pro Asn Ala Ser Leu Ile Gly Leu Thr Ala Thr 
                245                 250                 255     


Ala Thr Asn His Val Leu Thr Asp Ala Gln Lys Ile Leu Cys Ile Glu 
            260                 265                 270         


Lys Cys Phe Thr Phe Thr Ala Ser Phe Asn Arg Pro Asn Leu Tyr Tyr 
        275                 280                 285             


Glu Val Arg Gln Lys Pro Ser Asn Thr Glu Asp Phe Ile Glu Asp Ile 
    290                 295                 300                 


Val Lys Leu Ile Asn Gly Arg Tyr Lys Gly Gln Ser Gly Ile Ile Tyr 
305                 310                 315                 320 


Cys Phe Ser Gln Lys Asp Ser Glu Gln Val Thr Val Ser Leu Gln Asn 
                325                 330                 335     


Leu Gly Ile His Ala Gly Ala Tyr His Ala Asn Leu Glu Pro Glu Asp 
            340                 345                 350         


Lys Thr Thr Val His Arg Lys Trp Ser Ala Asn Glu Ile Gln Val Val 
        355                 360                 365             


Val Ala Thr Val Ala Phe Gly Met Gly Ile Asp Lys Pro Asp Val Arg 
    370                 375                 380                 


Phe Val Ile His His Ser Met Ser Lys Ser Met Glu Asn Tyr Tyr Gln 
385                 390                 395                 400 


Glu Ser Gly Arg Ala Gly Arg Asp Asp Met Lys Ala Asp Cys Ile Leu 
                405                 410                 415     


Tyr Tyr Gly Phe Gly Asp Ile Phe Arg Ile Ser Ser Met Val Val Met 
            420                 425                 430         


Glu Asn Val Gly Gln Gln Lys Leu Tyr Glu Met Val Ser Tyr Cys Gln 
        435                 440                 445             


Asn Ile Ser Lys Cys Arg Arg Val Leu Met Ala Gln His Phe Asp Glu 
    450                 455                 460                 


Val Trp Asn Ser Glu Ala Cys Asn Lys Met Cys Asp Asn Cys Cys Lys 
465                 470                 475                 480 


Asp Ser Ala Phe Glu Arg Lys Asn Ile Thr Glu Tyr Cys Arg Asp Leu 
                485                 490                 495     


Ile Lys Ile Leu Lys Gln Ala Glu Glu Leu Asn Glu Lys Leu Thr Pro 
            500                 505                 510         


Leu Lys Leu Ile Asp Ser Trp Met Gly Lys Gly Ala Ala Lys Leu Arg 
        515                 520                 525             


Val Ala Gly Val Val Ala Pro Thr Leu Pro Arg Glu Asp Leu Glu Lys 
    530                 535                 540                 


Ile Ile Ala His Phe Leu Ile Gln Gln Tyr Leu Lys Glu Asp Tyr Ser 
545                 550                 555                 560 


Phe Thr Ala Tyr Ala Thr Ile Ser Tyr Leu Lys Ile Gly Pro Lys Ala 
                565                 570                 575     


Asn Leu Leu Asn Asn Glu Ala His Ala Ile Thr Met Gln Val Thr Lys 
            580                 585                 590         


Ser Thr Gln Asn Ser Phe Arg Ala Glu Ser Ser Gln Thr Cys His Ser 
        595                 600                 605             


Glu Gln Gly Asp Lys Lys Met Glu Glu Lys Asn Ser Gly Asn Phe Gln 
    610                 615                 620                 


Lys Lys Ala Ala Asn Met Leu Gln Gln Ser Gly Ser Lys Asn Thr Gly 
625                 630                 635                 640 


Ala Lys Lys Arg Lys Ile Asp Asp Ala 
                645                 


<210>  2917
<211>  357
<212>  PRT
<213>  homo sapiens

<400>  2917

Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Pro Gly Gln Thr Pro Glu Ala Ala Lys Thr His Ser Val Glu Thr Pro 
            20                  25                  30          


Tyr Gly Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg 
        35                  40                  45              


Pro Ala Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys 
    50                  55                  60                  


Phe Gln Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn 
65                  70                  75                  80  


Phe Val Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro 
                85                  90                  95      


Val Phe Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp 
            100                 105                 110         


Met Ile Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly 
        115                 120                 125             


Val Gly Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn 
    130                 135                 140                 


His Pro Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn 
145                 150                 155                 160 


Ala Lys Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr 
                165                 170                 175     


Ser Ser Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu 
            180                 185                 190         


Leu Ser Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr 
        195                 200                 205             


His Ala Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn 
    210                 215                 220                 


Asn Arg Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg 
225                 230                 235                 240 


Cys Pro Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala 
                245                 250                 255     


Val Val Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu 
            260                 265                 270         


Lys Met Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Gln Pro Gly Lys 
        275                 280                 285             


Leu Thr Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr Met Ala 
    290                 295                 300                 


Ser Ser Cys Met Thr Arg Leu Ser Arg Ser Arg Thr Ala Ser Leu Thr 
305                 310                 315                 320 


Ser Ala Ala Ser Val Asp Gly Asn Arg Ser Arg Ser Arg Thr Leu Ser 
                325                 330                 335     


Gln Ser Ser Glu Ser Gly Thr Leu Ser Ser Gly Pro Pro Gly His Thr 
            340                 345                 350         


Met Glu Val Ser Cys 
        355         


<210>  2918
<211>  1014
<212>  PRT
<213>  homo sapiens

<400>  2918

Met Arg Val Pro Val Phe Glu Asp Ile Lys Asp Glu Thr Glu Glu Glu 
1               5                   10                  15      


Lys Ile Gly Glu Glu Glu Asn Glu Glu Asp Gln Val Phe Tyr Lys Pro 
            20                  25                  30          


Val Ile Glu Asp Leu Ser Met Glu Leu Ala Arg Lys Cys Thr Glu Leu 
        35                  40                  45              


Ile Ser Asp Ile Arg Tyr Lys Glu Glu Phe Lys Lys Ser Lys Asp Lys 
    50                  55                  60                  


Cys Thr Phe Val Thr Asp Ser Pro Met Leu Asn His Val Lys Asn Ile 
65                  70                  75                  80  


Gly Ala Phe Ile Ser Glu Ala Lys Tyr Lys Gly Thr Ile Lys Ala Asp 
                85                  90                  95      


Leu Ser Asn Ser Leu Tyr Lys Arg Met Pro Ala Thr Ile Asp Ser Val 
            100                 105                 110         


Phe Ala Gly Glu Val Thr Gln Leu Gln Ser Glu Val Ala Tyr Lys Gln 
        115                 120                 125             


Lys His Asp Ala Ala Lys Gly Phe Ser Asp Tyr Ala His Met Lys Glu 
    130                 135                 140                 


Pro Pro Glu Val Lys His Ala Met Glu Val Asn Lys His Gln Ser Asn 
145                 150                 155                 160 


Ile Ser Tyr Arg Lys Asp Val Gln Asp Thr His Thr Tyr Ser Ala Glu 
                165                 170                 175     


Leu Asp Arg Pro Asp Ile Lys Met Ala Thr Gln Ile Ser Lys Ile Ile 
            180                 185                 190         


Ser Asn Ala Glu Tyr Lys Lys Gly Gln Gly Ile Met Asn Lys Glu Pro 
        195                 200                 205             


Ala Val Ile Gly Arg Pro Asp Phe Glu His Ala Val Glu Ala Ser Lys 
    210                 215                 220                 


Leu Ser Ser Gln Ile Lys Tyr Lys Glu Lys Phe Asp Asn Glu Met Lys 
225                 230                 235                 240 


Asp Lys Lys His His Tyr Asn Pro Leu Glu Ser Ala Ser Phe Arg Gln 
                245                 250                 255     


Asn Gln Leu Ala Ala Thr Leu Ala Ser Asn Val Lys Tyr Lys Lys Asp 
            260                 265                 270         


Ile Gln Asn Met His Asp Pro Val Ser Asp Leu Pro Asn Leu Leu Phe 
        275                 280                 285             


Leu Asp His Val Leu Lys Ala Ser Lys Met Leu Ser Gly Arg Glu Tyr 
    290                 295                 300                 


Lys Lys Leu Phe Glu Glu Asn Lys Gly Met Tyr His Phe Asp Ala Asp 
305                 310                 315                 320 


Ala Val Glu His Leu His His Lys Gly Asn Ala Val Leu Gln Ser Gln 
                325                 330                 335     


Val Lys Tyr Lys Glu Glu Tyr Glu Lys Asn Lys Gly Lys Pro Met Leu 
            340                 345                 350         


Glu Phe Val Glu Thr Pro Ser Tyr Gln Ala Ser Lys Glu Ala Gln Lys 
        355                 360                 365             


Met Gln Ser Glu Lys Val Tyr Lys Glu Asp Phe Glu Lys Glu Ile Lys 
    370                 375                 380                 


Gly Arg Ser Ser Leu Asp Leu Asp Lys Thr Pro Glu Phe Leu His Val 
385                 390                 395                 400 


Lys Tyr Ile Thr Asn Leu Leu Arg Glu Lys Glu Tyr Lys Lys Asp Leu 
                405                 410                 415     


Glu Asn Glu Ile Lys Gly Lys Gly Met Glu Leu Asn Ser Glu Val Leu 
            420                 425                 430         


Asp Ile Gln Arg Ala Lys Arg Ala Ser Glu Met Ala Ser Glu Lys Glu 
        435                 440                 445             


Tyr Lys Lys Asp Leu Glu Ser Ile Ile Lys Gly Lys Gly Met Gln Ala 
    450                 455                 460                 


Gly Thr Asp Thr Leu Glu Met Gln His Ala Lys Lys Ala Ala Glu Ile 
465                 470                 475                 480 


Ala Ser Glu Lys Asp Tyr Lys Arg Asp Leu Glu Thr Glu Ile Lys Gly 
                485                 490                 495     


Lys Gly Met Gln Val Ser Thr Asp Thr Leu Asp Val Gln Arg Ala Lys 
            500                 505                 510         


Lys Ala Ser Glu Met Ala Ser Gln Lys Gln Tyr Lys Lys Asp Leu Glu 
        515                 520                 525             


Asn Glu Ile Lys Gly Lys Gly Met Gln Val Ser Met Asp Ile Pro Asp 
    530                 535                 540                 


Ile Leu Arg Ala Lys Arg Thr Ser Glu Ile Tyr Ser Gln Arg Lys Tyr 
545                 550                 555                 560 


Lys Asp Glu Ala Glu Lys Met Leu Ser Asn Tyr Ser Thr Ile Ala Asp 
                565                 570                 575     


Thr Pro Glu Ile Gln Arg Ile Lys Thr Thr Gln Gln Asn Ile Ser Ala 
            580                 585                 590         


Val Phe Tyr Lys Lys Glu Val Gly Ala Gly Thr Ala Val Lys Asp Ser 
        595                 600                 605             


Pro Glu Ile Glu Arg Val Lys Lys Asn Gln Gln Asn Ile Ser Ser Val 
    610                 615                 620                 


Lys Tyr Lys Glu Glu Ile Lys His Ala Thr Ala Ile Ser Asp Pro Pro 
625                 630                 635                 640 


Glu Leu Lys Arg Val Lys Glu Asn Gln Lys Asn Ile Ser Asn Leu Gln 
                645                 650                 655     


Tyr Lys Glu Gln Asn Tyr Lys Ala Thr Pro Val Ser Met Thr Pro Glu 
            660                 665                 670         


Ile Glu Arg Val Arg Arg Asn Gln Glu Gln Leu Ser Ala Val Lys Tyr 
        675                 680                 685             


Lys Gly Glu Leu Gln Arg Gly Thr Ala Ile Ser Asp Pro Pro Glu Leu 
    690                 695                 700                 


Lys Arg Ala Lys Glu Asn Gln Lys Asn Ile Ser Asn Val Tyr Tyr Arg 
705                 710                 715                 720 


Gly Gln Leu Gly Arg Ala Thr Thr Leu Ser Val Thr Pro Glu Met Glu 
                725                 730                 735     


Arg Val Lys Lys Asn Gln Glu Asn Ile Ser Ser Val Lys Tyr Thr Gln 
            740                 745                 750         


Asp His Lys Gln Met Lys Gly Arg Pro Ser Leu Ile Leu Asp Thr Pro 
        755                 760                 765             


Ala Met Arg His Val Lys Glu Ala Gln Asn His Ile Ser Met Val Lys 
    770                 775                 780                 


Tyr His Glu Asp Phe Glu Lys Thr Lys Gly Arg Gly Phe Thr Pro Val 
785                 790                 795                 800 


Val Asp Asp Pro Val Thr Glu Arg Val Arg Lys Asn Thr Gln Val Val 
                805                 810                 815     


Ser Asp Ala Ala Tyr Lys Gly Val His Pro His Ile Val Glu Met Asp 
            820                 825                 830         


Arg Arg Pro Gly Ile Ile Val Asp Leu Lys Val Trp Arg Thr Asp Pro 
        835                 840                 845             


Gly Ser Ile Phe Asp Leu Asp Pro Leu Glu Asp Asn Ile Gln Ser Arg 
    850                 855                 860                 


Ser Leu His Met Leu Ser Glu Lys Ala Ser His Tyr Arg Arg His Trp 
865                 870                 875                 880 


Ser Arg Ser His Ser Ser Ser Thr Phe Gly Thr Gly Leu Gly Asp Asp 
                885                 890                 895     


Arg Ser Glu Ile Ser Glu Ile Tyr Pro Ser Phe Ser Cys Cys Ser Glu 
            900                 905                 910         


Val Thr Arg Pro Ser Asp Glu Gly Ala Pro Val Leu Pro Gly Ala Tyr 
        915                 920                 925             


Gln Gln Ser His Ser Gln Gly Tyr Gly Tyr Met His Gln Thr Ser Val 
    930                 935                 940                 


Ser Ser Met Arg Ser Met Gln His Ser Pro Asn Leu Arg Thr Tyr Arg 
945                 950                 955                 960 


Ala Met Tyr Asp Tyr Ser Ala Gln Asp Glu Asp Glu Val Ser Phe Arg 
                965                 970                 975     


Asp Gly Asp Tyr Ile Val Asn Val Gln Pro Ile Asp Asp Gly Trp Met 
            980                 985                 990         


Tyr Gly Thr Val Gln Arg Thr Gly  Arg Thr Gly Met Leu  Pro Ala Asn 
        995                 1000                 1005             


Tyr Ile  Glu Phe Val Asn 
    1010                 


<210>  2919
<211>  149
<212>  PRT
<213>  homo sapiens

<400>  2919

Met Glu Lys Glu Glu Thr Thr Arg Glu Leu Leu Leu Pro Asn Trp Gln 
1               5                   10                  15      


Gly Ser Gly Ser His Gly Leu Thr Ile Ala Gln Arg Asp Asp Gly Val 
            20                  25                  30          


Phe Val Gln Glu Val Thr Gln Asn Ser Pro Ala Ala Arg Thr Gly Val 
        35                  40                  45              


Val Lys Glu Gly Asp Gln Ile Val Gly Ala Thr Ile Tyr Phe Asp Asn 
    50                  55                  60                  


Leu Gln Ser Gly Glu Val Thr Gln Leu Leu Asn Thr Met Gly His His 
65                  70                  75                  80  


Thr Val Gly Leu Lys Leu His Arg Lys Gly Asp Arg Ser Pro Glu Pro 
                85                  90                  95      


Gly Gln Thr Trp Thr Arg Glu Val Phe Ser Ser Cys Ser Ser Glu Val 
            100                 105                 110         


Val Leu Asn Thr Pro Gln Pro Ser Ala Leu Glu Cys Lys Asp Gln Asn 
        115                 120                 125             


Lys Gln Lys Glu Ala Ser Ser Gln Ala Gly Ala Val Ser Val Ser Thr 
    130                 135                 140                 


Pro Asn Ala Gly Leu 
145                 


<210>  2920
<211>  1048
<212>  PRT
<213>  homo sapiens

<400>  2920

Met Gln Ser Lys Val Thr Gly Asn Met Pro Thr Gln Ser Leu Leu Met 
1               5                   10                  15      


Tyr Met Asp Gly Pro Glu Val Ile Gly Ser Ser Leu Gly Ser Pro Met 
            20                  25                  30          


Glu Met Glu Asp Ala Leu Ser Met Lys Gly Thr Ala Val Val Pro Phe 
        35                  40                  45              


Arg Ala Thr Gln Glu Lys Asn Val Ile Gln Ile Glu Gly Tyr Met Pro 
    50                  55                  60                  


Leu Asp Cys Met Phe Cys Ser Gln Thr Phe Thr His Ser Glu Asp Leu 
65                  70                  75                  80  


Asn Lys His Val Leu Met Gln His Arg Pro Thr Leu Cys Glu Pro Ala 
                85                  90                  95      


Val Leu Arg Val Glu Ala Glu Tyr Leu Ser Pro Leu Asp Lys Ser Gln 
            100                 105                 110         


Val Arg Thr Glu Pro Pro Lys Glu Lys Asn Cys Lys Glu Asn Glu Phe 
        115                 120                 125             


Ser Cys Glu Val Cys Gly Gln Thr Phe Arg Val Ala Phe Asp Val Glu 
    130                 135                 140                 


Ile His Met Arg Thr His Lys Asp Ser Phe Thr Tyr Gly Cys Asn Met 
145                 150                 155                 160 


Cys Gly Arg Arg Phe Lys Glu Pro Trp Phe Leu Lys Asn His Met Arg 
                165                 170                 175     


Thr His Asn Gly Lys Ser Gly Ala Arg Ser Lys Leu Gln Gln Gly Leu 
            180                 185                 190         


Glu Ser Ser Pro Ala Thr Ile Asn Glu Val Val Gln Val His Ala Ala 
        195                 200                 205             


Glu Ser Ile Ser Ser Pro Tyr Lys Ile Cys Met Val Cys Gly Phe Leu 
    210                 215                 220                 


Phe Pro Asn Lys Glu Ser Leu Ile Glu His Arg Lys Val His Thr Lys 
225                 230                 235                 240 


Lys Thr Ala Phe Gly Thr Ser Ser Ala Gln Thr Asp Ser Pro Gln Gly 
                245                 250                 255     


Gly Met Pro Ser Ser Arg Glu Asp Phe Leu Gln Leu Phe Asn Leu Arg 
            260                 265                 270         


Pro Lys Ser His Pro Glu Thr Gly Lys Lys Pro Val Arg Cys Ile Pro 
        275                 280                 285             


Gln Leu Asp Pro Phe Thr Thr Phe Gln Ala Trp Gln Leu Ala Thr Lys 
    290                 295                 300                 


Gly Lys Val Ala Ile Cys Gln Glu Val Lys Glu Ser Gly Gln Glu Gly 
305                 310                 315                 320 


Ser Thr Asp Asn Asp Asp Ser Ser Ser Glu Lys Glu Leu Gly Glu Thr 
                325                 330                 335     


Asn Lys Gly Ser Cys Ala Gly Leu Ser Gln Glu Lys Glu Lys Cys Lys 
            340                 345                 350         


His Ser His Gly Glu Ala Pro Ser Val Asp Ala Asp Pro Lys Leu Pro 
        355                 360                 365             


Ser Ser Lys Glu Lys Pro Thr His Cys Ser Glu Cys Gly Lys Ala Phe 
    370                 375                 380                 


Arg Thr Tyr His Gln Leu Val Leu His Ser Arg Val His Lys Lys Asp 
385                 390                 395                 400 


Arg Arg Ala Gly Ala Glu Ser Pro Thr Met Ser Val Asp Gly Arg Gln 
                405                 410                 415     


Pro Gly Thr Cys Ser Pro Asp Leu Ala Ala Pro Leu Asp Glu Asn Gly 
            420                 425                 430         


Ala Val Asp Arg Gly Glu Gly Gly Ser Glu Asp Gly Ser Glu Asp Gly 
        435                 440                 445             


Leu Pro Glu Gly Ile His Leu Asp Lys Asn Asp Asp Gly Gly Lys Ile 
    450                 455                 460                 


Lys His Leu Thr Ser Ser Arg Glu Cys Ser Tyr Cys Gly Lys Phe Phe 
465                 470                 475                 480 


Arg Ser Asn Tyr Tyr Leu Asn Ile His Leu Arg Thr His Thr Gly Glu 
                485                 490                 495     


Lys Pro Tyr Lys Cys Glu Phe Cys Glu Tyr Ala Ala Ala Gln Lys Thr 
            500                 505                 510         


Ser Leu Arg Tyr His Leu Glu Arg His His Lys Glu Lys Gln Thr Asp 
        515                 520                 525             


Val Ala Ala Glu Val Lys Asn Asp Gly Lys Asn Gln Asp Thr Glu Asp 
    530                 535                 540                 


Ala Leu Leu Thr Ala Asp Ser Ala Gln Thr Lys Asn Leu Lys Arg Phe 
545                 550                 555                 560 


Phe Asp Gly Ala Lys Asp Val Thr Gly Ser Pro Pro Ala Lys Gln Leu 
                565                 570                 575     


Lys Glu Met Pro Ser Val Phe Gln Asn Val Leu Gly Ser Ala Val Leu 
            580                 585                 590         


Ser Pro Ala His Lys Asp Thr Gln Asp Phe His Lys Asn Ala Ala Asp 
        595                 600                 605             


Asp Ser Ala Asp Lys Val Asn Lys Asn Pro Thr Pro Ala Tyr Leu Asp 
    610                 615                 620                 


Leu Leu Lys Lys Arg Ser Ala Val Glu Thr Gln Ala Asn Asn Leu Ile 
625                 630                 635                 640 


Cys Arg Thr Lys Ala Asp Val Thr Pro Pro Pro Asp Gly Ser Thr Thr 
                645                 650                 655     


His Asn Leu Glu Val Ser Pro Lys Glu Lys Gln Thr Glu Thr Ala Ala 
            660                 665                 670         


Asp Cys Arg Tyr Arg Pro Ser Val Asp Cys His Glu Lys Pro Leu Asn 
        675                 680                 685             


Leu Ser Val Gly Ala Leu His Asn Cys Pro Ala Ile Ser Leu Ser Lys 
    690                 695                 700                 


Ser Leu Ile Pro Ser Ile Thr Cys Pro Phe Cys Thr Phe Lys Thr Phe 
705                 710                 715                 720 


Tyr Pro Glu Val Leu Met Met His Gln Arg Leu Glu His Lys Tyr Asn 
                725                 730                 735     


Pro Asp Val His Lys Asn Cys Arg Asn Lys Ser Leu Leu Arg Ser Arg 
            740                 745                 750         


Arg Thr Gly Cys Pro Pro Ala Leu Leu Gly Lys Asp Val Pro Pro Leu 
        755                 760                 765             


Ser Ser Phe Cys Lys Pro Lys Pro Lys Ser Ala Phe Pro Ala Gln Ser 
    770                 775                 780                 


Lys Ser Leu Pro Ser Ala Lys Gly Lys Gln Ser Pro Pro Gly Pro Gly 
785                 790                 795                 800 


Lys Ala Pro Leu Thr Ser Gly Ile Asp Ser Ser Thr Leu Ala Pro Ser 
                805                 810                 815     


Asn Leu Lys Ser His Arg Pro Gln Gln Asn Val Gly Val Gln Gly Ala 
            820                 825                 830         


Ala Thr Arg Gln Gln Gln Ser Glu Met Phe Pro Lys Thr Ser Val Ser 
        835                 840                 845             


Pro Ala Pro Asp Lys Thr Lys Arg Pro Glu Thr Lys Leu Lys Pro Leu 
    850                 855                 860                 


Pro Val Ala Pro Ser Gln Pro Thr Leu Gly Ser Ser Asn Ile Asn Gly 
865                 870                 875                 880 


Ser Ile Asp Tyr Pro Ala Lys Asn Asp Ser Pro Trp Ala Pro Pro Gly 
                885                 890                 895     


Arg Asp Tyr Phe Cys Asn Arg Ser Ala Ser Asn Thr Ala Ala Glu Phe 
            900                 905                 910         


Gly Glu Pro Leu Pro Lys Arg Leu Lys Ser Ser Val Val Ala Leu Asp 
        915                 920                 925             


Val Asp Gln Pro Gly Ala Asn Tyr Arg Arg Gly Tyr Asp Leu Pro Lys 
    930                 935                 940                 


Tyr His Met Val Arg Gly Ile Thr Ser Leu Leu Pro Gln Asp Cys Val 
945                 950                 955                 960 


Tyr Pro Ser Gln Ala Leu Pro Pro Lys Pro Arg Phe Leu Ser Ser Ser 
                965                 970                 975     


Glu Val Asp Ser Pro Asn Val Leu Thr Val Gln Lys Pro Tyr Gly Gly 
            980                 985                 990         


Ser Gly Pro Leu Tyr Thr Cys Val  Pro Ala Gly Ser Pro  Ala Ser Ser 
        995                 1000                 1005             


Ser Thr  Leu Glu Gly Lys Arg  Pro Val Ser Tyr Gln  His Leu Ser 
    1010                 1015                 1020             


Asn Ser  Met Ala Gln Lys Arg  Asn Tyr Glu Asn Phe  Ile Gly Asn 
    1025                 1030                 1035             


Ala His  Tyr Arg Pro Asn Asp  Lys Lys Thr 
    1040                 1045             


<210>  2921
<211>  1626
<212>  PRT
<213>  homo sapiens

<400>  2921

Met Ala Gly Leu Arg Gly Asn Ala Val Ala Gly Leu Leu Trp Met Leu 
1               5                   10                  15      


Leu Leu Trp Ser Gly Gly Gly Gly Cys Gln Ala Gln Arg Ala Gly Cys 
            20                  25                  30          


Lys Ser Val His Tyr Asp Leu Val Phe Leu Leu Asp Thr Ser Ser Ser 
        35                  40                  45              


Val Gly Lys Glu Asp Phe Glu Lys Val Arg Gln Trp Val Ala Asn Leu 
    50                  55                  60                  


Val Asp Thr Phe Glu Val Gly Pro Asp Arg Thr Arg Val Gly Val Val 
65                  70                  75                  80  


Arg Tyr Ser Asp Arg Pro Thr Thr Ala Phe Glu Leu Gly Leu Phe Gly 
                85                  90                  95      


Ser Gln Glu Glu Val Lys Ala Ala Ala Arg Arg Leu Ala Tyr His Gly 
            100                 105                 110         


Gly Asn Thr Asn Thr Gly Asp Ala Leu Arg Tyr Ile Thr Ala Arg Ser 
        115                 120                 125             


Phe Ser Pro His Ala Gly Gly Arg Pro Arg Asp Arg Ala Tyr Lys Gln 
    130                 135                 140                 


Val Ala Ile Leu Leu Thr Asp Gly Arg Ser Gln Asp Leu Val Leu Asp 
145                 150                 155                 160 


Ala Ala Ala Ala Ala His Arg Ala Gly Ile Arg Ile Phe Ala Val Gly 
                165                 170                 175     


Val Gly Glu Ala Leu Lys Glu Glu Leu Glu Glu Ile Ala Ser Glu Pro 
            180                 185                 190         


Lys Ser Ala His Val Phe His Val Ser Asp Phe Asn Ala Ile Asp Lys 
        195                 200                 205             


Ile Arg Gly Lys Leu Arg Arg Arg Leu Cys Glu Asn Val Leu Cys Pro 
    210                 215                 220                 


Ser Val Arg Val Glu Gly Asp Arg Phe Lys His Thr Asn Gly Gly Thr 
225                 230                 235                 240 


Lys Glu Ile Thr Gly Phe Asp Leu Met Asp Leu Phe Ser Val Lys Glu 
                245                 250                 255     


Ile Leu Gly Lys Arg Glu Asn Gly Ala Gln Ser Ser Tyr Val Arg Met 
            260                 265                 270         


Gly Ser Phe Pro Val Val Gln Ser Thr Glu Asp Val Phe Pro Gln Gly 
        275                 280                 285             


Leu Pro Asp Glu Tyr Ala Phe Val Thr Thr Phe Arg Phe Arg Lys Thr 
    290                 295                 300                 


Ser Arg Lys Glu Asp Trp Tyr Ile Trp Gln Val Ile Asp Gln Tyr Ser 
305                 310                 315                 320 


Ile Pro Gln Val Ser Ile Arg Leu Asp Gly Glu Asn Lys Ala Val Glu 
                325                 330                 335     


Tyr Asn Ala Val Gly Ala Met Lys Asp Ala Val Arg Val Val Phe Arg 
            340                 345                 350         


Gly Ser Arg Val Asn Asp Leu Phe Asp Arg Asp Trp His Lys Met Ala 
        355                 360                 365             


Leu Ser Ile Gln Ala Gln Asn Val Ser Leu His Ile Asp Cys Ala Leu 
    370                 375                 380                 


Val Gln Thr Leu Pro Ile Glu Glu Arg Glu Asn Ile Asp Ile Gln Gly 
385                 390                 395                 400 


Lys Thr Val Ile Gly Lys Arg Leu Tyr Asp Ser Val Pro Ile Asp Phe 
                405                 410                 415     


Asp Leu Gln Arg Ile Val Ile Tyr Cys Asp Ser Arg His Ala Glu Leu 
            420                 425                 430         


Glu Thr Cys Cys Asp Ile Pro Ser Gly Pro Cys Gln Val Thr Val Val 
        435                 440                 445             


Thr Glu Pro Pro Pro Pro Pro Pro Pro Gln Arg Pro Pro Thr Pro Gly 
    450                 455                 460                 


Ser Glu Gln Ile Gly Phe Leu Lys Thr Ile Asn Cys Ser Cys Pro Ala 
465                 470                 475                 480 


Gly Glu Lys Gly Glu Met Gly Val Ala Gly Pro Met Gly Leu Pro Gly 
                485                 490                 495     


Pro Lys Gly Asp Ile Gly Ala Ile Gly Pro Val Gly Ala Pro Gly Pro 
            500                 505                 510         


Lys Gly Glu Lys Gly Asp Val Gly Ile Gly Pro Phe Gly Gln Gly Glu 
        515                 520                 525             


Lys Gly Glu Lys Gly Ser Leu Gly Leu Pro Gly Pro Pro Gly Arg Asp 
    530                 535                 540                 


Gly Ser Lys Gly Met Arg Gly Glu Pro Gly Glu Leu Gly Glu Pro Gly 
545                 550                 555                 560 


Leu Pro Gly Glu Val Gly Met Arg Gly Pro Gln Gly Pro Pro Gly Leu 
                565                 570                 575     


Pro Gly Pro Pro Gly Arg Val Gly Ala Pro Gly Leu Gln Gly Glu Arg 
            580                 585                 590         


Gly Glu Lys Gly Thr Arg Gly Glu Lys Gly Glu Arg Gly Leu Asp Gly 
        595                 600                 605             


Phe Pro Gly Lys Pro Gly Asp Thr Gly Gln Gln Gly Arg Pro Gly Pro 
    610                 615                 620                 


Ser Gly Val Ala Gly Pro Gln Gly Glu Lys Gly Asp Val Gly Pro Ala 
625                 630                 635                 640 


Gly Pro Pro Gly Val Pro Gly Ser Val Val Gln Gln Glu Gly Leu Lys 
                645                 650                 655     


Gly Glu Gln Gly Ala Pro Gly Pro Arg Gly His Gln Gly Ala Pro Gly 
            660                 665                 670         


Pro Pro Gly Ala Arg Gly Pro Ile Gly Pro Glu Gly Arg Asp Gly Pro 
        675                 680                 685             


Pro Gly Leu Gln Gly Leu Arg Gly Lys Lys Gly Asp Met Gly Pro Pro 
    690                 695                 700                 


Gly Ile Pro Gly Leu Leu Gly Leu Gln Gly Pro Pro Gly Pro Pro Gly 
705                 710                 715                 720 


Val Pro Gly Pro Pro Gly Pro Gly Gly Ser Pro Gly Leu Pro Gly Glu 
                725                 730                 735     


Ile Gly Phe Pro Gly Lys Pro Gly Pro Pro Gly Pro Thr Gly Pro Pro 
            740                 745                 750         


Gly Lys Asp Gly Pro Asn Gly Pro Pro Gly Pro Pro Gly Thr Lys Gly 
        755                 760                 765             


Glu Pro Gly Glu Arg Gly Glu Asp Gly Leu Pro Gly Lys Pro Gly Leu 
    770                 775                 780                 


Arg Gly Glu Ile Gly Glu Gln Gly Leu Ala Gly Arg Pro Gly Glu Lys 
785                 790                 795                 800 


Gly Glu Ala Gly Leu Pro Gly Ala Pro Gly Phe Pro Gly Val Arg Gly 
                805                 810                 815     


Glu Lys Gly Asp Gln Gly Glu Lys Gly Glu Leu Gly Leu Pro Gly Leu 
            820                 825                 830         


Lys Gly Asp Arg Gly Glu Lys Gly Glu Ala Gly Pro Ala Gly Pro Pro 
        835                 840                 845             


Gly Leu Pro Gly Thr Thr Ser Leu Phe Thr Pro His Pro Arg Met Pro 
    850                 855                 860                 


Gly Glu Gln Gly Pro Lys Gly Glu Lys Gly Asp Pro Gly Leu Pro Gly 
865                 870                 875                 880 


Glu Pro Gly Leu Gln Gly Arg Pro Gly Glu Leu Gly Pro Gln Gly Pro 
                885                 890                 895     


Thr Gly Pro Pro Gly Ala Lys Gly Gln Glu Gly Ala His Gly Ala Pro 
            900                 905                 910         


Gly Ala Ala Gly Asn Pro Gly Ala Pro Gly His Val Gly Ala Pro Gly 
        915                 920                 925             


Pro Ser Gly Pro Pro Gly Ser Val Gly Ala Pro Gly Leu Arg Gly Thr 
    930                 935                 940                 


Pro Gly Lys Asp Gly Glu Arg Gly Glu Lys Gly Ala Ala Gly Glu Glu 
945                 950                 955                 960 


Gly Ser Pro Gly Pro Val Gly Pro Arg Gly Asp Pro Gly Ala Pro Gly 
                965                 970                 975     


Leu Pro Gly Pro Pro Gly Lys Gly Lys Asp Gly Glu Pro Gly Leu Arg 
            980                 985                 990         


Gly Ser Pro Gly Leu Pro Gly Pro  Leu Gly Thr Lys Ala  Ala Cys Gly 
        995                 1000                 1005             


Lys Val  Arg Gly Ser Glu Asn  Cys Ala Leu Gly Gly  Gln Cys Val 
    1010                 1015                 1020             


Lys Gly  Asp Arg Gly Ala Pro  Gly Ile Pro Gly Ser  Pro Gly Ser 
    1025                 1030                 1035             


Arg Gly  Asp Pro Gly Ile Gly  Val Ala Gly Pro Pro  Gly Pro Ser 
    1040                 1045                 1050             


Gly Pro  Pro Gly Asp Lys Gly  Ser Pro Gly Ser Arg  Gly Leu Pro 
    1055                 1060                 1065             


Gly Phe  Pro Gly Pro Gln Gly  Pro Ala Gly Arg Asp  Gly Ala Pro 
    1070                 1075                 1080             


Gly Asn  Pro Gly Glu Arg Gly  Pro Pro Gly Lys Pro  Gly Leu Ser 
    1085                 1090                 1095             


Ser Leu  Leu Ser Pro Gly Asp  Ile Asn Leu Leu Ala  Lys Asp Val 
    1100                 1105                 1110             


Cys Asn  Asp Cys Pro Pro Gly  Pro Pro Gly Leu Pro  Gly Leu Pro 
    1115                 1120                 1125             


Gly Phe  Lys Gly Asp Lys Gly  Val Pro Gly Lys Pro  Gly Arg Glu 
    1130                 1135                 1140             


Gly Thr  Glu Gly Lys Lys Gly  Glu Ala Gly Pro Pro  Gly Leu Pro 
    1145                 1150                 1155             


Gly Pro  Pro Gly Ile Ala Gly  Pro Gln Gly Ser Gln  Gly Glu Arg 
    1160                 1165                 1170             


Gly Ala  Asp Gly Glu Val Gly  Gln Lys Gly Asp Gln  Gly His Pro 
    1175                 1180                 1185             


Gly Val  Pro Gly Phe Met Gly  Pro Pro Gly Asn Pro  Gly Pro Pro 
    1190                 1195                 1200             


Gly Ala  Asp Gly Ile Ala Gly  Ala Ala Gly Pro Pro  Gly Ile Gln 
    1205                 1210                 1215             


Gly Ser  Pro Gly Lys Glu Gly  Pro Pro Gly Pro Gln  Gly Pro Ser 
    1220                 1225                 1230             


Gly Leu  Pro Gly Ile Pro Gly  Glu Glu Gly Lys Glu  Gly Arg Asp 
    1235                 1240                 1245             


Gly Lys  Pro Gly Pro Pro Gly  Glu Pro Gly Lys Ala  Gly Glu Pro 
    1250                 1255                 1260             


Gly Leu  Pro Gly Pro Glu Gly  Ala Arg Gly Pro Pro  Gly Phe Lys 
    1265                 1270                 1275             


Gly His  Thr Gly Asp Ser Gly  Ala Pro Gly Pro Arg  Gly Glu Ser 
    1280                 1285                 1290             


Gly Ala  Met Gly Leu Pro Gly  Gln Glu Gly Leu Pro  Gly Lys Asp 
    1295                 1300                 1305             


Gly Asp  Thr Gly Pro Thr Gly  Pro Gln Gly Pro Gln  Gly Pro Arg 
    1310                 1315                 1320             


Gly Pro  Pro Gly Lys Asn Gly  Ser Pro Gly Ser Pro  Gly Glu Pro 
    1325                 1330                 1335             


Gly Pro  Ser Gly Thr Pro Gly  Gln Lys Gly Ser Lys  Gly Glu Asn 
    1340                 1345                 1350             


Gly Ser  Pro Gly Leu Pro Gly  Phe Leu Gly Pro Arg  Gly Pro Pro 
    1355                 1360                 1365             


Gly Glu  Pro Gly Glu Lys Gly  Val Pro Gly Lys Glu  Gly Val Pro 
    1370                 1375                 1380             


Gly Lys  Pro Gly Glu Pro Gly  Phe Lys Gly Glu Arg  Gly Asp Pro 
    1385                 1390                 1395             


Gly Ile  Lys Gly Asp Lys Gly  Pro Pro Gly Gly Lys  Gly Gln Pro 
    1400                 1405                 1410             


Gly Asp  Pro Gly Ile Pro Gly  His Lys Gly His Thr  Gly Leu Met 
    1415                 1420                 1425             


Gly Pro  Gln Gly Leu Pro Gly  Glu Asn Gly Pro Val  Gly Pro Pro 
    1430                 1435                 1440             


Gly Pro  Pro Gly Gln Pro Gly  Phe Pro Gly Leu Arg  Gly Glu Ser 
    1445                 1450                 1455             


Pro Ser  Met Glu Thr Leu Arg  Arg Leu Ile Gln Glu  Glu Leu Gly 
    1460                 1465                 1470             


Lys Gln  Leu Glu Thr Arg Leu  Ala Tyr Leu Leu Ala  Gln Met Pro 
    1475                 1480                 1485             


Pro Ala  Tyr Met Lys Ser Ser  Gln Gly Arg Pro Gly  Pro Pro Gly 
    1490                 1495                 1500             


Pro Pro  Gly Lys Asp Gly Leu  Pro Gly Arg Ala Gly  Pro Met Gly 
    1505                 1510                 1515             


Glu Pro  Gly Arg Pro Gly Gln  Gly Gly Leu Glu Gly  Pro Ser Gly 
    1520                 1525                 1530             


Pro Ile  Gly Pro Lys Gly Glu  Arg Gly Ala Lys Gly  Asp Pro Gly 
    1535                 1540                 1545             


Ala Pro  Gly Val Gly Leu Arg  Gly Glu Met Gly Pro  Pro Gly Ile 
    1550                 1555                 1560             


Pro Gly  Gln Pro Gly Glu Pro  Gly Tyr Ala Lys Asp  Gly Leu Pro 
    1565                 1570                 1575             


Gly Ile  Pro Gly Pro Gln Gly  Glu Thr Gly Pro Ala  Gly His Pro 
    1580                 1585                 1590             


Gly Leu  Pro Gly Pro Pro Gly  Pro Pro Gly Gln Cys  Asp Pro Ser 
    1595                 1600                 1605             


Gln Cys  Ala Tyr Phe Ala Ser  Leu Ala Ala Arg Pro  Gly Asn Val 
    1610                 1615                 1620             


Lys Gly  Pro 
    1625     


<210>  2922
<211>  125
<212>  PRT
<213>  homo sapiens

<400>  2922

Met Gly Pro Gly Gly Pro Leu Leu Ser Pro Ser Arg Gly Phe Leu Leu 
1               5                   10                  15      


Cys Lys Thr Gly Trp His Ser Asn Arg Leu Leu Gly Asp Cys Gly Pro 
            20                  25                  30          


His Thr Pro Val Ser Thr Ala Leu Ser Phe Ile Ala Val Gly Met Ala 
        35                  40                  45              


Ala Pro Ser Met Lys Glu Arg Gln Val Cys Trp Gly Ala Arg Asp Glu 
    50                  55                  60                  


Tyr Trp Lys Cys Leu Asp Glu Asn Leu Glu Asp Ala Ser Gln Cys Lys 
65                  70                  75                  80  


Lys Leu Arg Ser Ser Phe Glu Ser Ser Cys Pro Gln Gln Trp Ile Lys 
                85                  90                  95      


Tyr Phe Asp Lys Arg Arg Asp Tyr Leu Lys Phe Lys Glu Lys Phe Glu 
            100                 105                 110         


Ala Gly Gln Phe Glu Pro Ser Glu Thr Thr Ala Lys Ser 
        115                 120                 125 


<210>  2923
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  2923

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  2924
<211>  1100
<212>  PRT
<213>  homo sapiens

<400>  2924

Met Ser Tyr Tyr Gln Arg Pro Phe Ser Pro Ser Ala Tyr Ser Leu Pro 
1               5                   10                  15      


Ala Ser Leu Asn Ser Ser Ile Val Met Gln His Gly Thr Ser Leu Asp 
            20                  25                  30          


Ser Thr Asp Thr Tyr Pro Gln His Ala Gln Ser Leu Asp Gly Thr Thr 
        35                  40                  45              


Ser Ser Ser Ile Pro Leu Tyr Arg Ser Ser Glu Glu Glu Lys Arg Val 
    50                  55                  60                  


Thr Val Ile Lys Ala Pro His Tyr Pro Gly Ile Gly Pro Val Asp Glu 
65                  70                  75                  80  


Ser Gly Ile Pro Thr Ala Ile Arg Thr Thr Val Asp Arg Pro Lys Asp 
                85                  90                  95      


Trp Tyr Lys Thr Met Phe Lys Gln Ile His Met Val His Lys Pro Asp 
            100                 105                 110         


Asp Asp Thr Asp Met Tyr Asn Thr Pro Tyr Thr Tyr Asn Ala Gly Leu 
        115                 120                 125             


Tyr Asn Pro Pro Tyr Ser Ala Gln Ser His Pro Ala Ala Lys Thr Gln 
    130                 135                 140                 


Thr Tyr Arg Pro Leu Ser Lys Ser His Ser Asp Asn Ser Pro Asn Ala 
145                 150                 155                 160 


Phe Lys Asp Ala Ser Ser Pro Val Pro Pro Pro His Val Pro Pro Pro 
                165                 170                 175     


Val Pro Pro Leu Arg Pro Arg Asp Arg Ser Ser Thr Glu Lys His Asp 
            180                 185                 190         


Trp Asp Pro Pro Asp Arg Lys Val Asp Thr Arg Lys Phe Arg Ser Glu 
        195                 200                 205             


Pro Arg Ser Ile Phe Glu Tyr Glu Pro Gly Lys Ser Ser Ile Leu Gln 
    210                 215                 220                 


His Glu Arg Pro Ala Ser Leu Tyr Gln Ser Ser Ile Asp Arg Ser Leu 
225                 230                 235                 240 


Glu Arg Pro Met Ser Ser Ala Ser Met Ala Ser Asp Phe Arg Lys Arg 
                245                 250                 255     


Arg Lys Ser Glu Pro Ala Val Gly Pro Pro Arg Gly Leu Gly Asp Gln 
            260                 265                 270         


Ser Ala Ser Arg Thr Ser Pro Gly Arg Val Asp Leu Pro Gly Ser Ser 
        275                 280                 285             


Thr Thr Leu Thr Lys Ser Phe Thr Ser Ser Ser Pro Ser Ser Pro Ser 
    290                 295                 300                 


Arg Ala Lys Gly Gly Asp Asp Ser Lys Ile Cys Pro Ser Leu Cys Ser 
305                 310                 315                 320 


Tyr Ser Gly Leu Asn Gly Asn Pro Ser Ser Glu Leu Asp Tyr Cys Ser 
                325                 330                 335     


Thr Tyr Arg Gln His Leu Asp Val Pro Arg Asp Ser Pro Arg Ala Ile 
            340                 345                 350         


Ser Phe Lys Asn Gly Trp Gln Met Ala Arg Gln Asn Ala Glu Ile Trp 
        355                 360                 365             


Ser Ser Thr Glu Glu Thr Val Ser Pro Lys Ile Lys Ser Arg Ser Cys 
    370                 375                 380                 


Asp Asp Leu Leu Asn Asp Asp Cys Asp Ser Phe Pro Asp Pro Lys Val 
385                 390                 395                 400 


Lys Ser Glu Ser Met Gly Ser Leu Leu Cys Glu Glu Asp Ser Lys Glu 
                405                 410                 415     


Ser Cys Pro Met Ala Trp Gly Ser Pro Tyr Val Pro Glu Val Arg Ser 
            420                 425                 430         


Asn Gly Arg Ser Arg Ile Arg His Arg Ser Ala Arg Asn Ala Pro Gly 
        435                 440                 445             


Phe Leu Lys Met Tyr Lys Lys Met His Arg Ile Asn Arg Lys Asp Leu 
    450                 455                 460                 


Met Asn Ser Glu Val Ile Cys Ser Val Lys Ser Arg Ile Leu Gln Tyr 
465                 470                 475                 480 


Glu Ser Glu Gln Gln His Lys Asp Leu Leu Arg Ala Trp Ser Gln Cys 
                485                 490                 495     


Ser Thr Glu Glu Val Pro Arg Asp Met Val Pro Thr Arg Ile Ser Glu 
            500                 505                 510         


Phe Glu Lys Leu Ile Gln Lys Ser Lys Ser Met Pro Asn Leu Gly Asp 
        515                 520                 525             


Asp Met Leu Ser Pro Val Thr Leu Glu Pro Pro Gln Asn Gly Leu Cys 
    530                 535                 540                 


Pro Lys Arg Arg Phe Ser Ile Glu Tyr Leu Leu Glu Glu Glu Asn Gln 
545                 550                 555                 560 


Ser Gly Pro Pro Ala Arg Gly Arg Arg Gly Cys Gln Ser Asn Ala Leu 
                565                 570                 575     


Val Pro Ile His Ile Glu Val Thr Ser Asp Glu Gln Pro Arg Ala His 
            580                 585                 590         


Val Glu Phe Ser Asp Ser Asp Gln Asp Gly Val Val Ser Asp His Ser 
        595                 600                 605             


Asp Tyr Ile His Leu Glu Gly Ser Ser Phe Cys Ser Glu Ser Asp Phe 
    610                 615                 620                 


Asp His Phe Ser Phe Thr Ser Ser Glu Ser Phe Tyr Gly Ser Ser His 
625                 630                 635                 640 


His His His His His His His His His His Arg His Leu Ile Ser Ser 
                645                 650                 655     


Cys Lys Gly Arg Cys Pro Ala Ser Tyr Thr Arg Phe Thr Thr Met Leu 
            660                 665                 670         


Lys His Glu Arg Ala Arg His Glu Asn Thr Glu Glu Pro Arg Arg Gln 
        675                 680                 685             


Glu Met Asp Pro Gly Leu Ser Lys Leu Ala Phe Leu Val Ser Pro Val 
    690                 695                 700                 


Pro Phe Arg Arg Lys Lys Asn Ser Ala Pro Lys Lys Gln Thr Glu Lys 
705                 710                 715                 720 


Ala Lys Cys Lys Ala Ser Val Phe Glu Ala Leu Asp Ser Ala Leu Lys 
                725                 730                 735     


Asp Ile Cys Asp Gln Ile Lys Ala Glu Lys Lys Arg Gly Ser Leu Pro 
            740                 745                 750         


Asp Asn Ser Ile Leu His Arg Leu Ile Ser Glu Leu Leu Pro Asp Val 
        755                 760                 765             


Pro Glu Arg Asn Ser Ser Leu Arg Ala Leu Arg Arg Ser Pro Leu His 
    770                 775                 780                 


Gln Pro Leu His Pro Leu Pro Pro Asp Gly Ala Ile His Cys Pro Pro 
785                 790                 795                 800 


Tyr Gln Asn Asp Cys Gly Arg Met Pro Arg Ser Ala Ser Phe Gln Asp 
                805                 810                 815     


Val Asp Thr Ala Asn Ser Ser Cys His His Gln Asp Arg Gly Gly Ala 
            820                 825                 830         


Leu Gln Asp Arg Glu Ser Pro Arg Ser Tyr Ser Ser Thr Leu Thr Asp 
        835                 840                 845             


Met Gly Arg Ser Ala Pro Arg Glu Arg Arg Gly Thr Pro Glu Lys Glu 
    850                 855                 860                 


Lys Leu Pro Ala Lys Ala Val Tyr Asp Phe Lys Ala Gln Thr Ser Lys 
865                 870                 875                 880 


Glu Leu Ser Phe Lys Lys Gly Asp Thr Val Tyr Ile Leu Arg Lys Ile 
                885                 890                 895     


Asp Gln Asn Trp Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe 
            900                 905                 910         


Pro Ile Ser Tyr Val Glu Lys Leu Thr Pro Pro Glu Lys Ala Gln Pro 
        915                 920                 925             


Ala Arg Pro Pro Pro Pro Ala Gln Pro Gly Glu Ile Gly Glu Ala Ile 
    930                 935                 940                 


Ala Lys Tyr Asn Phe Asn Ala Asp Thr Asn Val Glu Leu Ser Leu Arg 
945                 950                 955                 960 


Lys Gly Asp Arg Val Ile Leu Leu Lys Arg Val Asp Gln Asn Trp Tyr 
                965                 970                 975     


Glu Gly Lys Ile Pro Gly Thr Asn Arg Gln Gly Ile Phe Pro Val Ser 
            980                 985                 990         


Tyr Val Glu Val Val Lys Lys Asn  Thr Lys Gly Ala Glu  Asp Tyr Pro 
        995                 1000                 1005             


Asp Pro  Pro Ile Pro His Ser  Tyr Ser Ser Asp Arg  Ile His Ser 
    1010                 1015                 1020             


Leu Ser  Ser Asn Lys Pro Gln  Arg Pro Val Phe Thr  His Glu Asn 
    1025                 1030                 1035             


Ile Gln  Gly Gly Gly Glu Pro  Phe Gln Ala Leu Tyr  Asn Tyr Thr 
    1040                 1045                 1050             


Pro Arg  Asn Glu Asp Glu Leu  Glu Leu Arg Glu Ser  Asp Val Ile 
    1055                 1060                 1065             


Asp Val  Met Glu Lys Cys Asp  Asp Gly Trp Phe Val  Gly Thr Ser 
    1070                 1075                 1080             


Arg Arg  Thr Lys Phe Phe Gly  Thr Phe Pro Gly Asn  Tyr Val Lys 
    1085                 1090                 1095             


Arg Leu  
    1100 


<210>  2925
<211>  353
<212>  PRT
<213>  homo sapiens

<400>  2925

Met Glu Lys Thr Leu Glu Thr Val Pro Leu Glu Arg Lys Lys Arg Glu 
1               5                   10                  15      


Lys Glu Gln Phe Arg Lys Leu Phe Ile Gly Gly Leu Ser Phe Glu Thr 
            20                  25                  30          


Thr Glu Glu Ser Leu Arg Asn Tyr Tyr Glu Gln Trp Gly Lys Leu Thr 
        35                  40                  45              


Asp Cys Val Val Met Arg Asp Pro Ala Ser Lys Arg Ser Arg Gly Phe 
    50                  55                  60                  


Gly Phe Val Thr Phe Ser Ser Met Ala Glu Val Asp Ala Ala Met Ala 
65                  70                  75                  80  


Ala Arg Pro His Ser Ile Asp Gly Arg Val Val Glu Pro Lys Arg Ala 
                85                  90                  95      


Val Ala Arg Glu Glu Ser Gly Lys Pro Gly Ala His Val Thr Val Lys 
            100                 105                 110         


Lys Leu Phe Val Gly Gly Ile Lys Glu Asp Thr Glu Glu His His Leu 
        115                 120                 125             


Arg Asp Tyr Phe Glu Glu Tyr Gly Lys Ile Asp Thr Ile Glu Ile Ile 
    130                 135                 140                 


Thr Asp Arg Gln Ser Gly Lys Lys Arg Gly Phe Gly Phe Val Thr Phe 
145                 150                 155                 160 


Asp Asp His Asp Pro Val Asp Lys Ile Val Leu Gln Lys Tyr His Thr 
                165                 170                 175     


Ile Asn Gly His Asn Ala Glu Val Arg Lys Ala Leu Ser Arg Gln Glu 
            180                 185                 190         


Met Gln Glu Val Gln Ser Ser Arg Ser Gly Arg Gly Gly Asn Phe Gly 
        195                 200                 205             


Phe Gly Asp Ser Arg Gly Gly Gly Gly Asn Phe Gly Pro Gly Pro Gly 
    210                 215                 220                 


Ser Asn Phe Arg Gly Gly Ser Asp Gly Tyr Gly Ser Gly Arg Gly Phe 
225                 230                 235                 240 


Gly Asp Gly Tyr Asn Gly Tyr Gly Gly Gly Pro Gly Gly Gly Asn Phe 
                245                 250                 255     


Gly Gly Ser Pro Gly Tyr Gly Gly Gly Arg Gly Gly Tyr Gly Gly Gly 
            260                 265                 270         


Gly Pro Gly Tyr Gly Asn Gln Gly Gly Gly Tyr Gly Gly Gly Tyr Asp 
        275                 280                 285             


Asn Tyr Gly Gly Gly Asn Tyr Gly Ser Gly Asn Tyr Asn Asp Phe Gly 
    290                 295                 300                 


Asn Tyr Asn Gln Gln Pro Ser Asn Tyr Gly Pro Met Lys Ser Gly Asn 
305                 310                 315                 320 


Phe Gly Gly Ser Arg Asn Met Gly Gly Pro Tyr Gly Gly Gly Asn Tyr 
                325                 330                 335     


Gly Pro Gly Gly Ser Gly Gly Ser Gly Gly Tyr Gly Gly Arg Ser Arg 
            340                 345                 350         


Tyr 
    


<210>  2926
<211>  777
<212>  PRT
<213>  homo sapiens

<400>  2926

Met Arg Leu Lys Ile Ser Leu Leu Lys Glu Pro Lys His Gln Glu Leu 
1               5                   10                  15      


Val Ser Cys Val Gly Trp Thr Thr Ala Glu Glu Leu Tyr Ser Cys Ser 
            20                  25                  30          


Asp Asp His Gln Ile Val Lys Trp Asn Leu Leu Thr Ser Glu Thr Thr 
        35                  40                  45              


Gln Ile Val Lys Leu Pro Asp Asp Ile Tyr Pro Ile Asp Phe His Trp 
    50                  55                  60                  


Phe Pro Lys Ser Leu Gly Val Lys Lys Gln Thr Gln Ala Glu Ser Phe 
65                  70                  75                  80  


Val Leu Thr Ser Ser Asp Gly Lys Phe His Leu Ile Ser Lys Leu Gly 
                85                  90                  95      


Arg Val Glu Lys Ser Val Glu Ala His Cys Gly Ala Val Leu Ala Gly 
            100                 105                 110         


Arg Trp Asn Tyr Glu Gly Thr Ala Leu Val Thr Val Gly Glu Asp Gly 
        115                 120                 125             


Gln Ile Lys Ile Trp Ser Lys Thr Gly Met Leu Arg Ser Thr Leu Ala 
    130                 135                 140                 


Gln Gln Gly Thr Pro Val Tyr Ser Val Ala Trp Gly Pro Asp Ser Glu 
145                 150                 155                 160 


Lys Val Leu Tyr Thr Ala Gly Lys Gln Leu Ile Ile Lys Pro Leu Gln 
                165                 170                 175     


Pro Asn Ala Lys Val Leu Gln Trp Lys Ala His Asp Gly Ile Ile Leu 
            180                 185                 190         


Lys Val Asp Trp Asn Ser Val Asn Asp Leu Ile Leu Ser Ala Gly Glu 
        195                 200                 205             


Asp Cys Lys Tyr Lys Val Trp Asp Ser Tyr Gly Arg Pro Leu Tyr Asn 
    210                 215                 220                 


Ser Gln Pro His Glu His Pro Ile Thr Ser Val Ala Trp Ala Pro Asp 
225                 230                 235                 240 


Gly Glu Leu Phe Ala Val Gly Ser Phe His Thr Leu Arg Leu Cys Asp 
                245                 250                 255     


Lys Thr Gly Trp Ser Tyr Ala Leu Glu Lys Pro Asn Thr Gly Ser Ile 
            260                 265                 270         


Phe Asn Ile Ala Trp Ser Ile Asp Gly Thr Gln Ile Ala Gly Ala Cys 
        275                 280                 285             


Gly Asn Gly His Val Val Phe Ala His Val Val Glu Gln His Trp Glu 
    290                 295                 300                 


Trp Lys Asn Phe Gln Val Thr Leu Thr Lys Arg Arg Ala Met Gln Val 
305                 310                 315                 320 


Arg Asn Val Leu Asn Asp Ala Val Asp Leu Leu Glu Phe Arg Asp Arg 
                325                 330                 335     


Val Ile Lys Ala Ser Leu Asn Tyr Ala His Leu Val Val Ser Thr Ser 
            340                 345                 350         


Leu Gln Cys Tyr Val Phe Ser Thr Lys Asn Trp Asn Thr Pro Ile Ile 
        355                 360                 365             


Phe Asp Leu Lys Glu Gly Thr Val Ser Leu Ile Leu Gln Ala Glu Arg 
    370                 375                 380                 


His Phe Leu Leu Val Asp Gly Ser Ser Ile Tyr Leu Tyr Ser Tyr Glu 
385                 390                 395                 400 


Gly Arg Phe Ile Ser Ser Pro Lys Phe Pro Gly Met Arg Thr Asp Ile 
                405                 410                 415     


Leu Asn Ala Gln Thr Val Ser Leu Ser Asn Asp Thr Ile Ala Ile Arg 
            420                 425                 430         


Asp Lys Ala Asp Glu Lys Ile Ile Phe Leu Phe Glu Ala Ser Thr Gly 
        435                 440                 445             


Lys Pro Leu Gly Asp Gly Lys Phe Leu Ser His Lys Asn Glu Ile Leu 
    450                 455                 460                 


Glu Ile Ala Leu Asp Gln Lys Gly Leu Thr Asn Asp Arg Lys Ile Ala 
465                 470                 475                 480 


Phe Ile Asp Lys Asn Arg Asp Leu Cys Ile Thr Ser Val Lys Arg Phe 
                485                 490                 495     


Gly Lys Glu Glu Gln Ile Ile Lys Leu Gly Thr Met Val His Thr Leu 
            500                 505                 510         


Ala Trp Asn Asp Thr Cys Asn Ile Leu Cys Gly Leu Gln Asp Thr Arg 
        515                 520                 525             


Phe Ile Val Trp Tyr Tyr Pro Asn Thr Val Tyr Val Asp Arg Asp Ile 
    530                 535                 540                 


Leu Pro Lys Thr Leu Tyr Glu Arg Asp Ala Ser Glu Phe Ser Lys Asn 
545                 550                 555                 560 


Pro His Ile Val Ser Phe Val Gly Asn Gln Val Thr Ile Arg Arg Ala 
                565                 570                 575     


Asp Gly Ser Leu Val His Ile Ser Ile Thr Pro Tyr Pro Ala Ile Leu 
            580                 585                 590         


His Glu Tyr Val Ser Ser Ser Lys Trp Glu Asp Ala Val Arg Leu Cys 
        595                 600                 605             


Arg Phe Val Lys Glu Gln Thr Met Trp Ala Cys Leu Ala Ala Met Ala 
    610                 615                 620                 


Val Ala Asn Arg Asp Met Thr Thr Ala Glu Ile Ala Tyr Ala Ala Ile 
625                 630                 635                 640 


Gly Glu Ile Asp Lys Val Gln Tyr Ile Asn Ser Ile Lys Asn Leu Pro 
                645                 650                 655     


Ser Lys Glu Ser Lys Met Ala His Ile Leu Leu Phe Ser Gly Asn Ile 
            660                 665                 670         


Gln Glu Ala Glu Ile Val Leu Leu Gln Ala Gly Leu Val Tyr Gln Ala 
        675                 680                 685             


Ile Gln Ile Asn Ile Asn Leu Tyr Asn Trp Glu Arg Ala Leu Glu Leu 
    690                 695                 700                 


Ala Val Lys Tyr Lys Thr His Val Asp Thr Val Leu Ala Tyr Arg Gln 
705                 710                 715                 720 


Lys Phe Leu Glu Thr Phe Gly Lys Gln Glu Thr Asn Lys Arg Tyr Leu 
                725                 730                 735     


His Tyr Ala Glu Gly Leu Gln Ile Asp Trp Glu Lys Ile Lys Ala Lys 
            740                 745                 750         


Ile Glu Met Glu Ile Thr Lys Glu Arg Glu Gln Ser Ser Ser Ser Gln 
        755                 760                 765             


Ser Ser Lys Ser Ile Gly Leu Lys Pro 
    770                 775         


<210>  2927
<211>  753
<212>  PRT
<213>  homo sapiens

<400>  2927

Met Ala Asp Lys Arg Lys Leu Gln Gly Glu Ile Asp Arg Cys Leu Lys 
1               5                   10                  15      


Lys Val Ser Glu Gly Val Glu Gln Phe Glu Asp Ile Trp Gln Lys Leu 
            20                  25                  30          


His Asn Ala Ala Asn Ala Asn Gln Lys Glu Lys Tyr Glu Ala Asp Leu 
        35                  40                  45              


Lys Lys Glu Ile Lys Lys Leu Gln Arg Leu Arg Asp Gln Ile Lys Thr 
    50                  55                  60                  


Trp Val Ala Ser Asn Glu Ile Lys Asp Lys Arg Gln Leu Ile Asp Asn 
65                  70                  75                  80  


Arg Lys Leu Ile Glu Thr Gln Met Glu Arg Phe Lys Val Val Glu Arg 
                85                  90                  95      


Glu Thr Lys Thr Lys Ala Tyr Ser Lys Glu Gly Leu Gly Leu Ala Gln 
            100                 105                 110         


Lys Val Asp Pro Ala Gln Lys Glu Lys Glu Glu Val Gly Gln Trp Leu 
        115                 120                 125             


Thr Asn Thr Ile Asp Thr Leu Asn Met Gln Val Asp Gln Phe Glu Ser 
    130                 135                 140                 


Glu Val Glu Ser Leu Ser Val Gln Thr Arg Lys Lys Lys Gly Asp Lys 
145                 150                 155                 160 


Asp Lys Gln Asp Arg Ile Glu Gly Leu Lys Arg His Ile Glu Lys His 
                165                 170                 175     


Arg Tyr His Val Arg Met Leu Glu Thr Ile Leu Arg Met Leu Asp Asn 
            180                 185                 190         


Asp Ser Ile Leu Val Asp Ala Ile Arg Lys Ile Lys Asp Asp Val Glu 
        195                 200                 205             


Tyr Tyr Val Asp Ser Ser Gln Asp Pro Asp Phe Glu Glu Asn Glu Phe 
    210                 215                 220                 


Leu Tyr Asp Asp Leu Asp Leu Glu Asp Ile Pro Gln Ala Leu Val Ala 
225                 230                 235                 240 


Thr Ser Pro Pro Ser His Ser His Met Glu Asp Glu Ile Phe Asn Gln 
                245                 250                 255     


Ser Ser Ser Thr Pro Thr Ser Thr Thr Ser Ser Ser Pro Ile Pro Pro 
            260                 265                 270         


Ser Pro Ala Asn Cys Thr Thr Glu Asn Ser Glu Asp Asp Lys Lys Arg 
        275                 280                 285             


Gly Arg Ser Thr Asp Ser Glu Val Ser Gln Ser Pro Ala Lys Asn Gly 
    290                 295                 300                 


Ser Lys Pro Val His Ser Asn Gln His Pro Gln Ser Pro Ala Val Pro 
305                 310                 315                 320 


Pro Thr Tyr Pro Ser Gly Pro Pro Pro Ala Ala Ser Ala Leu Ser Thr 
                325                 330                 335     


Thr Pro Gly Asn Asn Gly Val Pro Ala Pro Ala Ala Pro Pro Ser Ala 
            340                 345                 350         


Leu Gly Pro Lys Ala Ser Pro Ala Pro Ser His Asn Ser Gly Thr Pro 
        355                 360                 365             


Ala Pro Tyr Ala Gln Ala Val Ala Pro Pro Ala Pro Ser Gly Pro Ser 
    370                 375                 380                 


Thr Thr Gln Pro Arg Pro Pro Ser Val Gln Pro Ser Gly Gly Gly Gly 
385                 390                 395                 400 


Gly Gly Ser Gly Gly Gly Gly Ser Ser Ser Ser Ser Asn Ser Ser Ala 
                405                 410                 415     


Gly Gly Gly Ala Gly Lys Gln Asn Gly Ala Thr Ser Tyr Ser Ser Val 
            420                 425                 430         


Val Ala Asp Ser Pro Ala Glu Val Ala Leu Ser Ser Ser Gly Gly Asn 
        435                 440                 445             


Asn Ala Ser Ser Gln Ala Leu Gly Pro Pro Ser Gly Pro His Asn Pro 
    450                 455                 460                 


Pro Pro Ser Thr Ser Lys Glu Pro Ser Ala Ala Ala Pro Thr Gly Ala 
465                 470                 475                 480 


Gly Gly Val Ala Pro Gly Ser Gly Asn Asn Ser Gly Gly Pro Ser Leu 
                485                 490                 495     


Leu Val Pro Leu Pro Val Asn Pro Pro Ser Ser Pro Thr Pro Ser Phe 
            500                 505                 510         


Ser Asp Ala Lys Ala Ala Gly Ala Leu Leu Asn Gly Pro Pro Gln Phe 
        515                 520                 525             


Ser Thr Ala Pro Glu Ile Lys Ala Pro Glu Pro Leu Ser Ser Leu Lys 
    530                 535                 540                 


Ser Met Ala Glu Arg Ala Ala Ile Ser Ser Gly Ile Glu Asp Pro Val 
545                 550                 555                 560 


Pro Thr Leu His Leu Thr Glu Arg Asp Ile Ile Leu Ser Ser Thr Ser 
                565                 570                 575     


Ala Pro Pro Ala Ser Ala Gln Pro Pro Leu Gln Leu Ser Glu Val Asn 
            580                 585                 590         


Ile Pro Leu Ser Leu Gly Val Cys Pro Leu Gly Pro Val Pro Leu Thr 
        595                 600                 605             


Lys Glu Gln Leu Tyr Gln Gln Ala Met Glu Glu Ala Ala Trp His His 
    610                 615                 620                 


Met Pro His Pro Ser Asp Ser Glu Arg Ile Arg Gln Tyr Leu Pro Arg 
625                 630                 635                 640 


Asn Pro Cys Pro Thr Pro Pro Tyr His His Gln Met Pro Pro Pro His 
                645                 650                 655     


Ser Asp Thr Val Glu Phe Tyr Gln Arg Leu Ser Thr Glu Thr Leu Phe 
            660                 665                 670         


Phe Ile Phe Tyr Tyr Leu Glu Gly Thr Lys Ala Gln Tyr Leu Ala Ala 
        675                 680                 685             


Lys Ala Leu Lys Lys Gln Ser Trp Arg Phe His Thr Lys Tyr Met Met 
    690                 695                 700                 


Trp Phe Gln Arg His Glu Glu Pro Lys Thr Ile Thr Asp Glu Phe Glu 
705                 710                 715                 720 


Gln Gly Thr Tyr Ile Tyr Phe Asp Tyr Glu Lys Trp Gly Gln Arg Lys 
                725                 730                 735     


Lys Glu Gly Phe Thr Phe Glu Tyr Arg Tyr Leu Glu Asp Arg Asp Leu 
            740                 745                 750         


Gln 
    


<210>  2928
<211>  1004
<212>  PRT
<213>  homo sapiens

<400>  2928

Met Val Gln Leu Tyr Asn Leu His Pro Phe Gly Ser Gln Gln Val Val 
1               5                   10                  15      


Pro Cys Lys Leu Glu Pro Asp Arg Phe Cys Gly Gly Gly Arg Asp Ala 
            20                  25                  30          


Leu Phe Val Ala Ala Gly Cys Lys Val Glu Ala Phe Ala Val Ala Gly 
        35                  40                  45              


Gln Glu Leu Cys Gln Pro Arg Cys Ala Phe Ser Thr Leu Gly Arg Val 
    50                  55                  60                  


Leu Arg Leu Ala Tyr Ser Glu Ala Gly Asp Tyr Leu Val Ala Ile Glu 
65                  70                  75                  80  


Glu Lys Asn Lys Ala Thr Phe Leu Arg Ala Tyr Val Asn Trp Arg Asn 
                85                  90                  95      


Lys Arg Thr Glu Asn Ser Arg Val Cys Ile Arg Met Ile Gly His Asn 
            100                 105                 110         


Val Glu Gly Pro Phe Ser Lys Ala Phe Arg Asp Gln Met Tyr Ile Ile 
        115                 120                 125             


Glu Met Pro Leu Ser Glu Ala Pro Leu Cys Ile Ser Cys Cys Pro Val 
    130                 135                 140                 


Lys Gly Asp Leu Leu Val Gly Cys Thr Asn Lys Leu Val Leu Phe Ser 
145                 150                 155                 160 


Leu Lys Tyr Gln Ile Ile Asn Glu Glu Phe Ser Leu Leu Asp Phe Glu 
                165                 170                 175     


Arg Ser Leu Ile Ile His Ile Asp Asn Ile Thr Pro Val Glu Val Ser 
            180                 185                 190         


Phe Cys Val Gly Tyr Val Ala Val Met Ser Asp Leu Glu Val Leu Ile 
        195                 200                 205             


Val Lys Leu Glu Ser Gly Pro Lys Asn Gly Glu Arg Val His His His 
    210                 215                 220                 


Pro His Lys Thr Asn Asn Arg Ile Arg Arg Thr Glu Glu Gly Ile Ser 
225                 230                 235                 240 


Asn Glu Ile Ser Gln Leu Glu Ser Asp Asp Phe Val Ile Cys Gln Lys 
                245                 250                 255     


Pro Leu Glu Leu Leu Gly Glu Lys Ser Glu Gln Ser Gly Leu Ser Val 
            260                 265                 270         


Thr Leu Glu Ser Thr Gly Leu Ala Asp Glu Lys Arg Lys Tyr Ser His 
        275                 280                 285             


Phe Gln His Leu Leu Tyr Arg Arg Phe Ala Pro Asp Ile Ser Ser Tyr 
    290                 295                 300                 


Val Leu Ser Asp Asp Ile Lys Leu His Ser Leu Gln Leu Leu Pro Ile 
305                 310                 315                 320 


Tyr Gln Thr Gly Ser Leu Thr Ser Asp Gly Lys Asn Leu Ser Gln Glu 
                325                 330                 335     


Lys Glu Leu Leu Ser Leu Phe Cys Phe Phe Ser Leu Pro His Val Gly 
            340                 345                 350         


Tyr Leu Tyr Met Val Val Lys Ser Val Glu Leu Met Ser Val Tyr Gln 
        355                 360                 365             


Tyr Pro Glu Lys Ser Gln Gln Ala Val Leu Thr Pro Gln Phe Leu His 
    370                 375                 380                 


Val Ile Thr Ser Asn Asn Leu Gln Cys Phe Thr Val Arg Cys Ser Ala 
385                 390                 395                 400 


Ala Ala Ala Arg Glu Glu Asp Pro Tyr Met Asp Thr Thr Leu Lys Ala 
                405                 410                 415     


Cys Pro Pro Val Ser Met Asp Val Cys Ala Leu Arg Ile Gln Leu Phe 
            420                 425                 430         


Ile Gly Leu Lys Ala Ile Cys His Phe Lys Asn His Ile Ile Leu Leu 
        435                 440                 445             


Thr Lys Ala Glu Pro Glu Ala Ile Pro Glu Arg Arg Gln Ser Pro Lys 
    450                 455                 460                 


Arg Leu Leu Ser Arg Lys Asp Thr Ser Val Lys Ile Lys Ile Pro Pro 
465                 470                 475                 480 


Val Ala Glu Ala Gly Trp Asn Leu Tyr Ile Val Asn Thr Ile Ser Pro 
                485                 490                 495     


Val Gln Leu Tyr Lys Glu Met Val Asp Tyr Ser Asn Thr Tyr Lys Thr 
            500                 505                 510         


Val Lys Thr Gln Ser Cys Ile His Leu Leu Ser Glu Ala His Leu Leu 
        515                 520                 525             


Val Arg Ala Ala Leu Met Asp Ala Ser Gln Leu Glu Pro Gly Glu Lys 
    530                 535                 540                 


Ala Glu Leu Leu Glu Ala Phe Lys Glu Ser Cys Gly His Leu Gly Asp 
545                 550                 555                 560 


Cys Tyr Ser Arg Leu Asp Ser Gln His Ser His Leu Thr Leu Pro Tyr 
                565                 570                 575     


Tyr Lys Met Ser Gly Leu Ser Met Ala Glu Val Leu Ala Arg Thr Asp 
            580                 585                 590         


Trp Thr Val Glu Asp Gly Leu Gln Lys Tyr Glu Arg Gly Leu Ile Phe 
        595                 600                 605             


Tyr Ile Asn His Ser Leu Tyr Glu Asn Leu Asp Glu Glu Leu Asn Glu 
    610                 615                 620                 


Glu Leu Ala Ala Lys Val Val Gln Met Phe Tyr Val Ala Glu Pro Lys 
625                 630                 635                 640 


Gln Val Pro His Ile Leu Cys Ser Pro Ser Met Lys Asn Ile Asn Pro 
                645                 650                 655     


Leu Thr Ala Met Ser Tyr Leu Arg Lys Leu Asp Thr Ser Gly Phe Ser 
            660                 665                 670         


Ser Ile Leu Val Thr Leu Thr Lys Ala Ala Val Ala Leu Lys Met Gly 
        675                 680                 685             


Asp Leu Asp Met His Arg Asn Glu Met Lys Ser His Ser Glu Met Lys 
    690                 695                 700                 


Leu Val Cys Gly Phe Ile Leu Glu Pro Arg Leu Leu Ile Gln Gln Arg 
705                 710                 715                 720 


Lys Gly Gln Ile Val Pro Thr Glu Leu Ala Leu His Leu Lys Glu Thr 
                725                 730                 735     


Gln Pro Gly Leu Leu Val Ala Ser Val Leu Gly Leu Gln Lys Asn Asn 
            740                 745                 750         


Lys Ile Gly Ile Glu Glu Ala Asp Ser Phe Phe Lys Val Leu Cys Ala 
        755                 760                 765             


Lys Asp Glu Asp Thr Ile Pro Gln Leu Leu Val Asp Phe Trp Glu Ala 
    770                 775                 780                 


Gln Leu Val Ala Cys Leu Pro Asp Val Val Leu Gln Glu Leu Phe Phe 
785                 790                 795                 800 


Lys Leu Thr Ser Gln Tyr Ile Trp Arg Leu Ser Lys Arg Gln Pro Pro 
                805                 810                 815     


Asp Thr Thr Pro Leu Arg Thr Ser Glu Asp Leu Ile Asn Ala Cys Ser 
            820                 825                 830         


His Tyr Gly Leu Ile Tyr Pro Trp Val His Val Val Ile Ser Ser Asp 
        835                 840                 845             


Ser Leu Ala Asp Lys Asn Tyr Thr Glu Asp Leu Ser Lys Leu Gln Ser 
    850                 855                 860                 


Leu Ile Cys Gly Pro Ser Phe Asp Ile Ala Ser Ile Ile Pro Phe Leu 
865                 870                 875                 880 


Glu Pro Leu Ser Glu Asp Thr Ile Ala Gly Leu Ser Val His Val Leu 
                885                 890                 895     


Cys Arg Thr Arg Leu Lys Glu Tyr Glu Gln Cys Ile Asp Ile Leu Leu 
            900                 905                 910         


Glu Arg Cys Pro Glu Ala Val Ile Pro Tyr Ala Asn His Glu Leu Lys 
        915                 920                 925             


Glu Glu Asn Arg Thr Leu Trp Trp Lys Lys Leu Leu Pro Glu Leu Cys 
    930                 935                 940                 


Gln Arg Ile Lys Cys Gly Gly Glu Lys Tyr Gln Leu Tyr Leu Ser Ser 
945                 950                 955                 960 


Leu Lys Glu Thr Leu Ser Ile Val Ala Val Glu Leu Glu Leu Lys Asp 
                965                 970                 975     


Phe Met Asn Val Leu Pro Glu Asp Gly Thr Ala Thr Phe Phe Leu Pro 
            980                 985                 990         


Tyr Leu Leu Tyr Cys Ser Arg Lys  Lys Pro Leu Thr 
        995                 1000                 


<210>  2929
<211>  442
<212>  PRT
<213>  homo sapiens

<400>  2929

Met Ala Ser Val Val Leu Pro Ser Gly Ser Gln Cys Ala Ala Ala Ala 
1               5                   10                  15      


Ala Ala Ala Ala Pro Pro Gly Leu Arg Leu Arg Leu Leu Leu Leu Leu 
            20                  25                  30          


Phe Ser Ala Ala Ala Leu Ile Pro Thr Gly Asp Gly Gln Asn Leu Phe 
        35                  40                  45              


Thr Lys Asp Val Thr Val Ile Glu Gly Glu Val Ala Thr Ile Ser Cys 
    50                  55                  60                  


Gln Val Asn Lys Ser Asp Asp Ser Val Ile Gln Leu Leu Asn Pro Asn 
65                  70                  75                  80  


Arg Gln Thr Ile Tyr Phe Arg Asp Phe Arg Pro Leu Lys Asp Ser Arg 
                85                  90                  95      


Phe Gln Leu Leu Asn Phe Ser Ser Ser Glu Leu Lys Val Ser Leu Thr 
            100                 105                 110         


Asn Val Ser Ile Ser Asp Glu Gly Arg Tyr Phe Cys Gln Leu Tyr Thr 
        115                 120                 125             


Asp Pro Pro Gln Glu Ser Tyr Thr Thr Ile Thr Val Leu Val Pro Pro 
    130                 135                 140                 


Arg Asn Leu Met Ile Asp Ile Gln Lys Asp Thr Ala Val Glu Gly Glu 
145                 150                 155                 160 


Glu Ile Glu Val Asn Cys Thr Ala Met Ala Ser Lys Pro Ala Thr Thr 
                165                 170                 175     


Ile Arg Trp Phe Lys Gly Asn Thr Glu Leu Lys Gly Lys Ser Glu Val 
            180                 185                 190         


Glu Glu Trp Ser Asp Met Tyr Thr Val Thr Ser Gln Leu Met Leu Lys 
        195                 200                 205             


Val His Lys Glu Asp Asp Gly Val Pro Val Ile Cys Gln Val Glu His 
    210                 215                 220                 


Pro Ala Val Thr Gly Asn Leu Gln Thr Gln Arg Tyr Leu Glu Val Gln 
225                 230                 235                 240 


Tyr Lys Pro Gln Val His Ile Gln Met Thr Tyr Pro Leu Gln Gly Leu 
                245                 250                 255     


Thr Arg Glu Gly Asp Ala Leu Glu Leu Thr Cys Glu Ala Ile Gly Lys 
            260                 265                 270         


Pro Gln Pro Val Met Val Thr Trp Val Arg Val Asp Asp Glu Met Pro 
        275                 280                 285             


Gln His Ala Val Leu Ser Gly Pro Asn Leu Phe Ile Asn Asn Leu Asn 
    290                 295                 300                 


Lys Thr Asp Asn Gly Thr Tyr Arg Cys Glu Ala Ser Asn Ile Val Gly 
305                 310                 315                 320 


Lys Ala His Ser Asp Tyr Met Leu Tyr Val Tyr Asp Pro Pro Thr Thr 
                325                 330                 335     


Ile Pro Pro Pro Thr Thr Thr Thr Thr Thr Thr Thr Thr Thr Thr Thr 
            340                 345                 350         


Thr Ile Leu Thr Ile Ile Thr Asp Ser Arg Ala Gly Glu Glu Gly Ser 
        355                 360                 365             


Ile Arg Ala Val Asp His Ala Val Ile Gly Gly Val Val Ala Val Val 
    370                 375                 380                 


Val Phe Ala Met Leu Cys Leu Leu Ile Ile Leu Gly Arg Tyr Phe Ala 
385                 390                 395                 400 


Arg His Lys Gly Thr Tyr Phe Thr His Glu Ala Lys Gly Ala Asp Asp 
                405                 410                 415     


Ala Ala Asp Ala Asp Thr Ala Ile Ile Asn Ala Glu Gly Gly Gln Asn 
            420                 425                 430         


Asn Ser Glu Glu Lys Lys Glu Tyr Phe Ile 
        435                 440         


<210>  2930
<211>  1691
<212>  PRT
<213>  homo sapiens

<400>  2930

Met Leu Ile Asn Lys Leu Trp Leu Leu Leu Val Thr Leu Cys Leu Thr 
1               5                   10                  15      


Glu Glu Leu Ala Ala Ala Gly Glu Lys Ser Tyr Gly Lys Pro Cys Gly 
            20                  25                  30          


Gly Gln Asp Cys Ser Gly Ser Cys Gln Cys Phe Pro Glu Lys Gly Ala 
        35                  40                  45              


Arg Gly Arg Pro Gly Pro Ile Gly Ile Gln Gly Pro Thr Gly Pro Gln 
    50                  55                  60                  


Gly Phe Thr Gly Ser Thr Gly Leu Ser Gly Leu Lys Gly Glu Arg Gly 
65                  70                  75                  80  


Phe Pro Gly Leu Leu Gly Pro Tyr Gly Pro Lys Gly Asp Lys Gly Pro 
                85                  90                  95      


Met Gly Val Pro Gly Phe Leu Gly Ile Asn Gly Ile Pro Gly His Pro 
            100                 105                 110         


Gly Gln Pro Gly Pro Arg Gly Pro Pro Gly Leu Asp Gly Cys Asn Gly 
        115                 120                 125             


Thr Gln Gly Ala Val Gly Phe Pro Gly Pro Asp Gly Tyr Pro Gly Leu 
    130                 135                 140                 


Leu Gly Pro Pro Gly Leu Pro Gly Gln Lys Gly Ser Lys Gly Asp Pro 
145                 150                 155                 160 


Val Leu Ala Pro Gly Ser Phe Lys Gly Met Lys Gly Asp Pro Gly Leu 
                165                 170                 175     


Pro Gly Leu Asp Gly Ile Thr Gly Pro Gln Gly Ala Pro Gly Phe Pro 
            180                 185                 190         


Gly Ala Val Gly Pro Ala Gly Pro Pro Gly Leu Gln Gly Pro Pro Gly 
        195                 200                 205             


Pro Pro Gly Pro Leu Gly Pro Asp Gly Asn Met Gly Leu Gly Phe Gln 
    210                 215                 220                 


Gly Glu Lys Gly Val Lys Gly Asp Val Gly Leu Pro Gly Pro Ala Gly 
225                 230                 235                 240 


Pro Pro Pro Ser Thr Gly Glu Leu Glu Phe Met Gly Phe Pro Lys Gly 
                245                 250                 255     


Lys Lys Gly Ser Lys Gly Glu Pro Gly Pro Lys Gly Phe Pro Gly Ile 
            260                 265                 270         


Ser Gly Pro Pro Gly Phe Pro Gly Leu Gly Thr Thr Gly Glu Lys Gly 
        275                 280                 285             


Glu Lys Gly Glu Lys Gly Ile Pro Gly Leu Pro Gly Pro Arg Gly Pro 
    290                 295                 300                 


Met Gly Ser Glu Gly Val Gln Gly Pro Pro Gly Gln Gln Gly Lys Lys 
305                 310                 315                 320 


Gly Thr Leu Gly Phe Pro Gly Leu Asn Gly Phe Gln Gly Ile Glu Gly 
                325                 330                 335     


Gln Lys Gly Asp Ile Gly Leu Pro Gly Pro Asp Val Phe Ile Asp Ile 
            340                 345                 350         


Asp Gly Ala Val Ile Ser Gly Asn Pro Gly Asp Pro Gly Val Pro Gly 
        355                 360                 365             


Leu Pro Gly Leu Lys Gly Asp Glu Gly Ile Gln Gly Leu Arg Gly Pro 
    370                 375                 380                 


Ser Gly Val Pro Gly Leu Pro Ala Leu Ser Gly Val Pro Gly Ala Leu 
385                 390                 395                 400 


Gly Pro Gln Gly Phe Pro Gly Leu Lys Gly Asp Gln Gly Asn Pro Gly 
                405                 410                 415     


Arg Thr Thr Ile Gly Ala Ala Gly Leu Pro Gly Arg Asp Gly Leu Pro 
            420                 425                 430         


Gly Pro Pro Gly Pro Pro Gly Pro Pro Ser Pro Glu Phe Glu Thr Glu 
        435                 440                 445             


Thr Leu His Asn Lys Glu Ser Gly Phe Pro Gly Leu Arg Gly Glu Gln 
    450                 455                 460                 


Gly Pro Lys Gly Asn Leu Gly Leu Lys Gly Ile Lys Gly Asp Ser Gly 
465                 470                 475                 480 


Phe Cys Ala Cys Asp Gly Gly Val Pro Asn Thr Gly Pro Pro Gly Glu 
                485                 490                 495     


Pro Gly Pro Pro Gly Pro Trp Gly Leu Ile Gly Leu Pro Gly Leu Lys 
            500                 505                 510         


Gly Ala Arg Gly Asp Arg Gly Ser Gly Gly Ala Gln Gly Pro Ala Gly 
        515                 520                 525             


Ala Pro Gly Leu Val Gly Pro Leu Gly Pro Ser Gly Pro Lys Gly Lys 
    530                 535                 540                 


Lys Gly Glu Pro Ile Leu Ser Thr Ile Gln Gly Met Pro Gly Asp Arg 
545                 550                 555                 560 


Gly Asp Ser Gly Ser Gln Gly Phe Arg Gly Val Ile Gly Glu Pro Gly 
                565                 570                 575     


Lys Asp Gly Val Pro Gly Leu Pro Gly Leu Pro Gly Leu Pro Gly Asp 
            580                 585                 590         


Gly Gly Gln Gly Phe Pro Gly Glu Lys Gly Leu Pro Gly Leu Pro Gly 
        595                 600                 605             


Glu Lys Gly His Pro Gly Pro Pro Gly Leu Pro Gly Asn Gly Leu Pro 
    610                 615                 620                 


Gly Leu Pro Gly Pro Arg Gly Leu Pro Gly Asp Lys Gly Lys Asp Gly 
625                 630                 635                 640 


Leu Pro Gly Gln Gln Gly Leu Pro Gly Ser Lys Gly Ile Thr Leu Pro 
                645                 650                 655     


Cys Ile Ile Pro Gly Ser Tyr Gly Pro Ser Gly Phe Pro Gly Thr Pro 
            660                 665                 670         


Gly Phe Pro Gly Pro Lys Gly Ser Arg Gly Leu Pro Gly Thr Pro Gly 
        675                 680                 685             


Gln Pro Gly Ser Ser Gly Ser Lys Gly Glu Pro Gly Ser Pro Gly Leu 
    690                 695                 700                 


Val His Leu Pro Glu Leu Pro Gly Phe Pro Gly Pro Arg Gly Glu Lys 
705                 710                 715                 720 


Gly Leu Pro Gly Phe Pro Gly Leu Pro Gly Lys Asp Gly Leu Pro Gly 
                725                 730                 735     


Met Ile Gly Ser Pro Gly Leu Pro Gly Ser Lys Gly Ala Thr Gly Asp 
            740                 745                 750         


Ile Phe Gly Ala Glu Asn Gly Ala Pro Gly Glu Gln Gly Leu Gln Gly 
        755                 760                 765             


Leu Thr Gly His Lys Gly Phe Leu Gly Asp Ser Gly Leu Pro Gly Leu 
    770                 775                 780                 


Lys Gly Val His Gly Lys Pro Gly Leu Leu Gly Pro Lys Gly Glu Arg 
785                 790                 795                 800 


Gly Ser Pro Gly Thr Pro Gly Gln Val Gly Gln Pro Gly Thr Pro Gly 
                805                 810                 815     


Ser Ser Gly Pro Tyr Gly Ile Lys Gly Lys Ser Gly Leu Pro Gly Ala 
            820                 825                 830         


Pro Gly Phe Pro Gly Ile Ser Gly His Pro Gly Lys Lys Gly Thr Arg 
        835                 840                 845             


Gly Lys Lys Gly Pro Pro Gly Ser Ile Val Lys Lys Gly Leu Pro Gly 
    850                 855                 860                 


Leu Lys Gly Leu Pro Gly Asn Pro Gly Leu Val Gly Leu Lys Gly Ser 
865                 870                 875                 880 


Pro Gly Ser Pro Gly Val Ala Gly Leu Pro Ala Leu Ser Gly Pro Lys 
                885                 890                 895     


Gly Glu Lys Gly Ser Val Gly Phe Val Gly Phe Pro Gly Ile Pro Gly 
            900                 905                 910         


Leu Pro Gly Ile Pro Gly Thr Arg Gly Leu Lys Gly Ile Pro Gly Ser 
        915                 920                 925             


Thr Gly Lys Met Gly Pro Ser Gly Arg Ala Gly Thr Pro Gly Glu Lys 
    930                 935                 940                 


Gly Asp Arg Gly Asn Pro Gly Pro Val Gly Ile Pro Ser Pro Arg Arg 
945                 950                 955                 960 


Pro Met Ser Asn Leu Trp Leu Lys Gly Asp Lys Gly Ser Gln Gly Ser 
                965                 970                 975     


Ala Gly Ser Asn Gly Phe Pro Gly Pro Arg Gly Asp Lys Gly Glu Ala 
            980                 985                 990         


Gly Arg Pro Gly Pro Pro Gly Leu  Pro Gly Ala Pro Gly  Leu Pro Gly 
        995                 1000                 1005             


Ile Ile  Lys Gly Val Ser Gly  Lys Pro Gly Pro Pro  Gly Phe Met 
    1010                 1015                 1020             


Gly Ile  Arg Gly Leu Pro Gly  Leu Lys Gly Ser Ser  Gly Ile Thr 
    1025                 1030                 1035             


Gly Phe  Pro Gly Met Pro Gly  Glu Ser Gly Ser Gln  Gly Ile Arg 
    1040                 1045                 1050             


Gly Ser  Pro Gly Leu Pro Gly  Ala Ser Gly Leu Pro  Gly Leu Lys 
    1055                 1060                 1065             


Gly Asp  Asn Gly Gln Thr Val  Glu Ile Ser Gly Ser  Pro Gly Pro 
    1070                 1075                 1080             


Lys Gly  Gln Pro Gly Glu Ser  Gly Phe Lys Gly Thr  Lys Gly Arg 
    1085                 1090                 1095             


Asp Gly  Leu Ile Gly Asn Ile  Gly Phe Pro Gly Asn  Lys Gly Glu 
    1100                 1105                 1110             


Asp Gly  Lys Val Gly Val Ser  Gly Asp Val Gly Leu  Pro Gly Ala 
    1115                 1120                 1125             


Pro Gly  Phe Pro Gly Val Ala  Gly Met Arg Gly Glu  Pro Gly Leu 
    1130                 1135                 1140             


Pro Gly  Ser Ser Gly His Gln  Gly Ala Ile Gly Pro  Leu Gly Ser 
    1145                 1150                 1155             


Pro Gly  Leu Ile Gly Pro Lys  Gly Phe Pro Gly Phe  Pro Gly Leu 
    1160                 1165                 1170             


His Gly  Leu Asn Gly Leu Pro  Gly Thr Lys Gly Thr  His Gly Thr 
    1175                 1180                 1185             


Pro Gly  Pro Ser Ile Thr Gly  Val Pro Gly Pro Ala  Gly Leu Pro 
    1190                 1195                 1200             


Gly Pro  Lys Gly Glu Lys Gly  Tyr Pro Gly Ile Gly  Ile Gly Ala 
    1205                 1210                 1215             


Pro Gly  Lys Pro Gly Leu Arg  Gly Gln Lys Gly Asp  Arg Gly Phe 
    1220                 1225                 1230             


Pro Gly  Leu Gln Gly Pro Ala  Gly Leu Pro Gly Ala  Pro Gly Ile 
    1235                 1240                 1245             


Ser Leu  Pro Ser Leu Ile Ala  Gly Gln Pro Gly Asp  Pro Gly Arg 
    1250                 1255                 1260             


Pro Gly  Leu Asp Gly Glu Arg  Gly Arg Pro Gly Pro  Ala Gly Pro 
    1265                 1270                 1275             


Pro Gly  Pro Pro Gly Pro Ser  Ser Asn Gln Gly Asp  Thr Gly Asp 
    1280                 1285                 1290             


Pro Gly  Phe Pro Gly Ile Pro  Gly Pro Lys Gly Pro  Lys Gly Asp 
    1295                 1300                 1305             


Gln Gly  Ile Pro Gly Phe Ser  Gly Leu Pro Gly Glu  Leu Gly Leu 
    1310                 1315                 1320             


Lys Gly  Met Arg Gly Glu Pro  Gly Phe Met Gly Thr  Pro Gly Lys 
    1325                 1330                 1335             


Val Gly  Pro Pro Gly Asp Pro  Gly Phe Pro Gly Met  Lys Gly Lys 
    1340                 1345                 1350             


Ala Gly  Pro Arg Gly Ser Ser  Gly Leu Gln Gly Asp  Pro Gly Gln 
    1355                 1360                 1365             


Thr Pro  Thr Ala Glu Ala Val  Gln Val Pro Pro Gly  Pro Leu Gly 
    1370                 1375                 1380             


Leu Pro  Gly Ile Asp Gly Ile  Pro Gly Leu Thr Gly  Asp Pro Gly 
    1385                 1390                 1395             


Ala Gln  Gly Pro Val Gly Leu  Gln Gly Ser Lys Gly  Leu Pro Gly 
    1400                 1405                 1410             


Ile Pro  Gly Lys Asp Gly Pro  Ser Gly Leu Pro Gly  Pro Pro Gly 
    1415                 1420                 1425             


Ala Leu  Gly Asp Pro Gly Leu  Pro Gly Leu Gln Gly  Pro Pro Gly 
    1430                 1435                 1440             


Phe Glu  Gly Ala Pro Gly Gln  Gln Gly Pro Phe Gly  Met Pro Gly 
    1445                 1450                 1455             


Met Pro  Gly Gln Ser Met Arg  Val Gly Tyr Thr Leu  Val Lys His 
    1460                 1465                 1470             


Ser Gln  Ser Glu Gln Val Pro  Pro Cys Pro Ile Gly  Met Ser Gln 
    1475                 1480                 1485             


Leu Trp  Val Gly Tyr Ser Leu  Leu Phe Val Glu Gly  Gln Glu Lys 
    1490                 1495                 1500             


Ala His  Asn Gln Asp Leu Gly  Phe Ala Gly Ser Cys  Leu Pro Arg 
    1505                 1510                 1515             


Phe Ser  Thr Met Pro Phe Ile  Tyr Cys Asn Ile Asn  Glu Val Cys 
    1520                 1525                 1530             


His Tyr  Ala Arg Arg Asn Asp  Lys Ser Tyr Trp Leu  Ser Thr Thr 
    1535                 1540                 1545             


Ala Pro  Ile Pro Met Met Pro  Val Ser Gln Thr Gln  Ile Pro Gln 
    1550                 1555                 1560             


Tyr Ile  Ser Arg Cys Ser Val  Cys Glu Ala Pro Ser  Gln Ala Ile 
    1565                 1570                 1575             


Ala Val  His Ser Gln Asp Ile  Thr Ile Pro Gln Cys  Pro Leu Gly 
    1580                 1585                 1590             


Trp Arg  Ser Leu Trp Ile Gly  Tyr Ser Phe Leu Met  His Thr Ala 
    1595                 1600                 1605             


Ala Gly  Ala Glu Gly Gly Gly  Gln Ser Leu Val Ser  Pro Gly Ser 
    1610                 1615                 1620             


Cys Leu  Glu Asp Phe Arg Ala  Thr Pro Phe Ile Glu  Cys Ser Gly 
    1625                 1630                 1635             


Ala Arg  Gly Thr Cys His Tyr  Phe Ala Asn Lys Tyr  Ser Phe Trp 
    1640                 1645                 1650             


Leu Thr  Thr Val Glu Glu Arg  Gln Gln Phe Gly Glu  Leu Pro Val 
    1655                 1660                 1665             


Ser Glu  Thr Leu Lys Ala Gly  Gln Leu His Thr Arg  Val Ser Arg 
    1670                 1675                 1680             


Cys Gln  Val Cys Met Lys Ser  Leu 
    1685                 1690     


<210>  2931
<211>  787
<212>  PRT
<213>  homo sapiens

<400>  2931

Met Glu Pro Ala Gly Glu Arg Phe Pro Glu Gln Arg Gln Val Leu Ile 
1               5                   10                  15      


Leu Leu Leu Leu Leu Glu Val Thr Leu Ala Gly Trp Glu Pro Arg Arg 
            20                  25                  30          


Tyr Ser Val Met Glu Glu Thr Glu Arg Gly Ser Phe Val Ala Asn Leu 
        35                  40                  45              


Ala Asn Asp Leu Gly Leu Gly Val Gly Glu Leu Ala Glu Arg Gly Ala 
    50                  55                  60                  


Arg Val Val Ser Glu Asp Asn Glu Gln Gly Leu Gln Leu Asp Leu Gln 
65                  70                  75                  80  


Thr Gly Gln Leu Ile Leu Asn Glu Lys Leu Asp Arg Glu Lys Leu Cys 
                85                  90                  95      


Gly Pro Thr Glu Pro Cys Ile Met His Phe Gln Val Leu Leu Lys Lys 
            100                 105                 110         


Pro Leu Glu Val Phe Arg Ala Glu Leu Leu Val Thr Asp Ile Asn Asp 
        115                 120                 125             


His Ser Pro Glu Phe Pro Glu Arg Glu Met Thr Leu Lys Ile Pro Glu 
    130                 135                 140                 


Thr Ser Ser Leu Gly Thr Val Phe Pro Leu Lys Lys Ala Arg Asp Leu 
145                 150                 155                 160 


Asp Val Gly Ser Asn Asn Val Gln Asn Tyr Asn Ile Ser Pro Asn Ser 
                165                 170                 175     


His Phe His Val Ser Thr Arg Thr Arg Gly Asp Gly Arg Lys Tyr Pro 
            180                 185                 190         


Glu Leu Val Leu Asp Thr Glu Leu Asp Arg Glu Glu Gln Ala Glu Leu 
        195                 200                 205             


Arg Leu Thr Leu Thr Ala Val Asp Gly Gly Ser Pro Pro Arg Ser Gly 
    210                 215                 220                 


Thr Val Gln Ile Leu Ile Leu Val Leu Asp Ala Asn Asp Asn Ala Pro 
225                 230                 235                 240 


Glu Phe Val Gln Ala Leu Tyr Glu Val Gln Val Pro Glu Asn Ser Pro 
                245                 250                 255     


Val Gly Ser Leu Val Val Lys Val Ser Ala Arg Asp Leu Asp Thr Gly 
            260                 265                 270         


Thr Asn Gly Glu Ile Ser Tyr Ser Leu Tyr Tyr Ser Ser Gln Glu Ile 
        275                 280                 285             


Asp Lys Pro Phe Glu Leu Ser Ser Leu Ser Gly Glu Ile Arg Leu Ile 
    290                 295                 300                 


Lys Lys Leu Asp Phe Glu Thr Met Ser Ser Tyr Asp Leu Asp Ile Glu 
305                 310                 315                 320 


Ala Ser Asp Gly Gly Gly Leu Ser Gly Lys Cys Ser Val Ser Val Lys 
                325                 330                 335     


Val Leu Asp Val Asn Asp Asn Phe Pro Glu Leu Ser Ile Ser Ser Leu 
            340                 345                 350         


Thr Ser Pro Ile Pro Glu Asn Ser Pro Glu Thr Glu Val Ala Leu Phe 
        355                 360                 365             


Arg Ile Arg Asp Arg Asp Ser Gly Glu Asn Gly Lys Met Ile Cys Ser 
    370                 375                 380                 


Ile Gln Asp Asp Val Pro Phe Lys Leu Lys Pro Ser Val Glu Asn Phe 
385                 390                 395                 400 


Tyr Arg Leu Val Thr Glu Gly Ala Leu Asp Arg Glu Thr Arg Ala Glu 
                405                 410                 415     


Tyr Asn Ile Thr Ile Thr Ile Thr Asp Leu Gly Thr Pro Arg Leu Lys 
            420                 425                 430         


Thr Glu Gln Ser Ile Thr Val Leu Val Ser Asp Val Asn Asp Asn Ala 
        435                 440                 445             


Pro Ala Phe Thr Gln Thr Ser Tyr Thr Leu Phe Val Arg Glu Asn Asn 
    450                 455                 460                 


Ser Pro Ala Leu His Ile Gly Ser Val Ser Ala Thr Asp Arg Asp Ser 
465                 470                 475                 480 


Gly Thr Asn Ala Gln Val Thr Tyr Ser Leu Leu Pro Pro Arg Asp Pro 
                485                 490                 495     


His Leu Pro Leu Thr Ser Leu Val Ser Ile Asn Thr Asp Asn Gly His 
            500                 505                 510         


Leu Phe Ala Leu Gln Ser Leu Asp Tyr Glu Ala Leu Gln Ala Phe Glu 
        515                 520                 525             


Phe Arg Val Gly Ala Thr Asp Arg Gly Phe Pro Ala Leu Ser Ser Glu 
    530                 535                 540                 


Ala Leu Val Arg Val Leu Val Leu Asp Ala Asn Asp Asn Ser Pro Phe 
545                 550                 555                 560 


Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala Pro Cys Thr Glu Leu Val 
                565                 570                 575     


Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val Thr Lys Val Val Ala Val 
            580                 585                 590         


Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu Ser Tyr Gln Leu Leu Lys 
        595                 600                 605             


Ala Thr Glu Pro Gly Leu Phe Gly Val Trp Ala His Asn Gly Glu Val 
    610                 615                 620                 


Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp Val Ala Lys His Arg Leu 
625                 630                 635                 640 


Val Val Leu Val Lys Asp Asn Gly Glu Pro Pro Arg Ser Ala Thr Ala 
                645                 650                 655     


Thr Leu Gln Val Leu Leu Val Asp Gly Phe Ser Gln Pro Tyr Leu Pro 
            660                 665                 670         


Leu Pro Glu Ala Ala Pro Ala Gln Ala Gln Ala Asp Ser Leu Thr Val 
        675                 680                 685             


Tyr Leu Val Val Ala Leu Ala Ser Val Ser Ser Leu Phe Leu Phe Ser 
    690                 695                 700                 


Val Phe Leu Phe Val Ala Val Arg Leu Cys Arg Arg Ser Arg Ala Ala 
705                 710                 715                 720 


Ser Val Gly Arg Cys Ser Val Pro Glu Gly Pro Phe Pro Gly His Leu 
                725                 730                 735     


Val Asp Val Ser Gly Thr Gly Thr Leu Ser Gln Ser Tyr Gln Tyr Glu 
            740                 745                 750         


Val Cys Leu Thr Gly Gly Ser Glu Ser Asn Asp Phe Lys Phe Leu Lys 
        755                 760                 765             


Pro Ile Phe Pro Asn Ile Val Ser Gln Asp Ser Arg Arg Lys Ser Glu 
    770                 775                 780                 


Phe Leu Glu 
785         


<210>  2932
<211>  795
<212>  PRT
<213>  homo sapiens

<400>  2932

Met Glu Thr Ala Leu Ala Lys Thr Pro Gln Lys Arg Gln Val Met Phe 
1               5                   10                  15      


Leu Ala Ile Leu Leu Leu Leu Trp Glu Ala Gly Ser Glu Ala Val Arg 
            20                  25                  30          


Tyr Ser Ile Pro Glu Glu Thr Glu Ser Gly Tyr Ser Val Ala Asn Leu 
        35                  40                  45              


Ala Lys Asp Leu Gly Leu Gly Val Gly Glu Leu Ala Thr Arg Gly Ala 
    50                  55                  60                  


Arg Met His Tyr Lys Gly Asn Lys Glu Leu Leu Gln Leu Asp Ile Lys 
65                  70                  75                  80  


Thr Gly Asn Leu Leu Leu Tyr Glu Lys Leu Asp Arg Glu Val Met Cys 
                85                  90                  95      


Gly Ala Thr Glu Pro Cys Ile Leu His Phe Gln Leu Leu Leu Glu Asn 
            100                 105                 110         


Pro Val Gln Phe Phe Gln Thr Asp Leu Gln Leu Thr Asp Ile Asn Asp 
        115                 120                 125             


His Ala Pro Glu Phe Pro Glu Lys Glu Met Leu Leu Lys Ile Pro Glu 
    130                 135                 140                 


Ser Thr Gln Pro Gly Thr Val Phe Pro Leu Lys Ile Ala Gln Asp Phe 
145                 150                 155                 160 


Asp Ile Gly Ser Asn Thr Val Gln Asn Tyr Thr Ile Ser Pro Asn Ser 
                165                 170                 175     


His Phe His Val Ala Thr His Asn Arg Gly Asp Gly Arg Lys Tyr Pro 
            180                 185                 190         


Glu Leu Val Leu Asp Lys Ala Leu Asp Arg Glu Glu Arg Pro Glu Leu 
        195                 200                 205             


Ser Leu Thr Leu Thr Ala Leu Asp Gly Gly Ala Pro Pro Arg Ser Gly 
    210                 215                 220                 


Thr Thr Thr Ile Arg Ile Val Val Leu Asp Asn Asn Asp Asn Ala Pro 
225                 230                 235                 240 


Glu Phe Leu Gln Ser Phe Tyr Glu Val Gln Val Pro Glu Asn Ser Pro 
                245                 250                 255     


Leu Asn Ser Leu Val Val Val Val Ser Ala Arg Asp Leu Asp Ala Gly 
            260                 265                 270         


Ala Tyr Gly Ser Val Ala Tyr Ala Leu Phe Gln Gly Asp Glu Val Thr 
        275                 280                 285             


Gln Pro Phe Val Ile Asp Glu Lys Thr Ala Glu Ile Arg Leu Lys Arg 
    290                 295                 300                 


Ala Leu Asp Phe Glu Ala Thr Pro Tyr Tyr Asn Val Glu Ile Val Ala 
305                 310                 315                 320 


Thr Asp Gly Gly Gly Leu Ser Gly Lys Cys Thr Val Ala Ile Glu Val 
                325                 330                 335     


Val Asp Val Asn Asp Asn Ala Pro Glu Leu Thr Met Ser Thr Leu Ser 
            340                 345                 350         


Ser Pro Thr Pro Glu Asn Ala Pro Glu Thr Val Val Ala Val Phe Ser 
        355                 360                 365             


Val Ser Asp Pro Asp Ser Gly Asp Asn Gly Arg Met Ile Cys Ser Ile 
    370                 375                 380                 


Gln Asn Asp Leu Pro Phe Leu Leu Lys Pro Thr Leu Lys Asn Phe Tyr 
385                 390                 395                 400 


Thr Leu Val Thr Gln Arg Thr Leu Asp Arg Glu Ser Gln Ala Glu Tyr 
                405                 410                 415     


Asn Ile Thr Ile Thr Val Thr Asp Met Gly Thr Pro Arg Leu Lys Thr 
            420                 425                 430         


Glu His Asn Ile Thr Val Leu Val Ser Asp Val Asn Asp Asn Ala Pro 
        435                 440                 445             


Ala Phe Thr Gln Thr Ser Tyr Thr Leu Phe Val Arg Glu Asn Asn Ser 
    450                 455                 460                 


Pro Ala Leu His Ile Gly Ser Val Ser Ala Thr Asp Arg Asp Ser Gly 
465                 470                 475                 480 


Thr Asn Ala Gln Val Thr Tyr Ser Leu Leu Pro Pro Gln Asn Pro His 
                485                 490                 495     


Leu Arg Leu Ala Ser Leu Val Ser Ile Asn Ala Asp Asn Gly His Leu 
            500                 505                 510         


Phe Ala Leu Arg Ser Leu Asp Tyr Glu Ala Leu Gln Ala Phe Glu Phe 
        515                 520                 525             


Arg Val Gly Ala Thr Asp Arg Gly Ser Pro Ala Leu Ser Ser Glu Ala 
    530                 535                 540                 


Leu Val Arg Val Leu Val Leu Asp Ala Asn Asp Asn Ser Pro Phe Val 
545                 550                 555                 560 


Leu Tyr Pro Leu Gln Asn Gly Ser Ala Pro Cys Thr Glu Leu Val Pro 
                565                 570                 575     


Arg Ala Ala Glu Pro Gly Tyr Leu Val Thr Lys Val Val Ala Val Asp 
            580                 585                 590         


Gly Asp Ser Gly Gln Asn Ala Trp Leu Ser Tyr Gln Leu Leu Lys Ala 
        595                 600                 605             


Thr Glu Pro Gly Leu Phe Ser Met Trp Ala His Asn Gly Glu Val Arg 
    610                 615                 620                 


Thr Ala Arg Leu Leu Ser Glu Arg Asp Ala Ala Lys His Arg Leu Val 
625                 630                 635                 640 


Val Leu Val Lys Asp Asn Gly Glu Pro Pro Arg Ser Ala Thr Ala Thr 
                645                 650                 655     


Leu His Val Leu Leu Val Asp Gly Phe Ser Gln Pro Tyr Leu Pro Leu 
            660                 665                 670         


Pro Glu Ala Ala Pro Ala Gln Ala Gln Ala Asp Ser Leu Thr Val Tyr 
        675                 680                 685             


Leu Val Val Ala Leu Ala Ser Val Ser Ser Leu Phe Leu Phe Ser Val 
    690                 695                 700                 


Leu Leu Phe Val Ala Val Arg Leu Cys Arg Arg Ser Arg Ala Ala Pro 
705                 710                 715                 720 


Val Gly Arg Cys Ser Val Pro Glu Gly Pro Phe Pro Gly His Leu Val 
                725                 730                 735     


Asp Val Ser Gly Thr Gly Thr Leu Ser Gln Ser Tyr His Tyr Glu Val 
            740                 745                 750         


Cys Leu Thr Gly Asp Ser Gly Ala Gly Glu Phe Lys Phe Leu Lys Pro 
        755                 760                 765             


Ile Ile Pro Asn Leu Leu Pro Gln Gly Ala Gly Glu Glu Ile Gly Lys 
    770                 775                 780                 


Thr Ala Ala Phe Arg Asn Ser Phe Gly Leu Asn 
785                 790                 795 


<210>  2933
<211>  1539
<212>  PRT
<213>  homo sapiens

<400>  2933

Met Asp Ser Tyr Phe Lys Ala Ala Val Ser Asp Leu Asp Lys Leu Leu 
1               5                   10                  15      


Asp Asp Phe Glu Gln Asn Pro Asp Glu Gln Asp Tyr Leu Gln Asp Val 
            20                  25                  30          


Gln Asn Ala Tyr Asp Ser Asn His Cys Ser Val Ser Ser Glu Leu Ala 
        35                  40                  45              


Ser Ser Gln Arg Thr Ser Leu Leu Pro Lys Asp Gln Glu Cys Val Asn 
    50                  55                  60                  


Ser Cys Ala Ser Ser Glu Thr Ser Tyr Gly Thr Asn Glu Ser Ser Leu 
65                  70                  75                  80  


Asn Glu Lys Thr Leu Lys Gly Leu Thr Ser Ile Gln Asn Glu Lys Asn 
                85                  90                  95      


Val Thr Gly Leu Asp Leu Leu Ser Ser Val Asp Gly Gly Thr Ser Asp 
            100                 105                 110         


Glu Ile Gln Pro Leu Tyr Met Gly Arg Cys Ser Lys Pro Ile Cys Asp 
        115                 120                 125             


Leu Ile Ser Asp Met Gly Asn Leu Val His Ala Thr Asn Ser Glu Glu 
    130                 135                 140                 


Asp Ile Lys Lys Leu Leu Pro Asp Asp Phe Lys Ser Asn Ala Asp Ser 
145                 150                 155                 160 


Leu Ile Gly Leu Asp Leu Ser Ser Val Ser Asp Thr Pro Cys Val Ser 
                165                 170                 175     


Ser Thr Asp His Asp Ser Asp Thr Val Arg Glu Gln Gln Asn Asp Ile 
            180                 185                 190         


Ser Ser Glu Leu Gln Asn Arg Glu Ile Gly Gly Ile Lys Glu Leu Gly 
        195                 200                 205             


Ile Lys Val Asp Thr Thr Leu Ser Asp Ser Tyr Asn Tyr Ser Gly Thr 
    210                 215                 220                 


Glu Asn Leu Lys Asp Lys Lys Ile Phe Asn Gln Leu Glu Ser Ile Val 
225                 230                 235                 240 


Asp Phe Asn Met Ser Ser Ala Leu Thr Arg Gln Ser Ser Lys Met Phe 
                245                 250                 255     


His Ala Lys Asp Lys Leu Gln His Lys Ser Gln Pro Cys Gly Leu Leu 
            260                 265                 270         


Lys Asp Val Gly Leu Val Lys Glu Glu Val Asp Val Ala Val Ile Thr 
        275                 280                 285             


Ala Ala Glu Cys Leu Lys Glu Glu Gly Lys Thr Ser Ala Leu Thr Cys 
    290                 295                 300                 


Ser Leu Pro Lys Asn Glu Asp Leu Cys Leu Asn Asp Ser Asn Ser Arg 
305                 310                 315                 320 


Asp Glu Asn Phe Lys Leu Pro Asp Phe Ser Phe Gln Glu Asp Lys Thr 
                325                 330                 335     


Val Ile Lys Gln Ser Ala Gln Glu Asp Ser Lys Ser Leu Asp Leu Lys 
            340                 345                 350         


Asp Asn Asp Val Ile Gln Asp Ser Ser Ser Ala Leu His Val Ser Ser 
        355                 360                 365             


Lys Asp Val Pro Ser Ser Leu Ser Cys Leu Pro Ala Ser Gly Ser Met 
    370                 375                 380                 


Cys Gly Ser Leu Ile Glu Ser Lys Ala Arg Gly Asp Phe Leu Pro Gln 
385                 390                 395                 400 


His Glu His Lys Asp Asn Ile Gln Asp Ala Val Thr Ile His Glu Glu 
                405                 410                 415     


Ile Gln Asn Ser Val Val Leu Gly Gly Glu Pro Phe Lys Glu Asn Asp 
            420                 425                 430         


Leu Leu Lys Gln Glu Lys Cys Lys Ser Ile Leu Leu Gln Ser Leu Ile 
        435                 440                 445             


Glu Gly Met Glu Asp Arg Lys Ile Asp Pro Asp Gln Thr Val Ile Arg 
    450                 455                 460                 


Ala Glu Ser Leu Asp Gly Gly Asp Thr Ser Ser Thr Val Val Glu Ser 
465                 470                 475                 480 


Gln Glu Gly Leu Ser Gly Thr His Val Pro Glu Ser Ser Asp Cys Cys 
                485                 490                 495     


Glu Gly Phe Ile Asn Thr Phe Ser Ser Asn Asp Met Asp Gly Gln Asp 
            500                 505                 510         


Leu Asp Tyr Phe Asn Ile Asp Glu Gly Ala Lys Ser Gly Pro Leu Ile 
        515                 520                 525             


Ser Asp Ala Glu Leu Asp Ala Phe Leu Thr Glu Gln Tyr Leu Gln Thr 
    530                 535                 540                 


Thr Asn Ile Lys Ser Phe Glu Glu Asn Val Asn Asp Ser Lys Ser Gln 
545                 550                 555                 560 


Met Asn Gln Ile Asp Met Lys Gly Leu Asp Asp Gly Asn Ile Asn Asn 
                565                 570                 575     


Ile Tyr Phe Asn Ala Glu Ala Gly Ala Ile Gly Glu Ser His Gly Ile 
            580                 585                 590         


Asn Ile Ile Cys Glu Thr Val Asp Lys Gln Asn Thr Ile Glu Asn Gly 
        595                 600                 605             


Leu Ser Leu Gly Glu Lys Ser Thr Ile Pro Val Gln Gln Gly Leu Pro 
    610                 615                 620                 


Thr Ser Lys Ser Glu Ile Thr Asn Gln Leu Ser Val Ser Asp Ile Asn 
625                 630                 635                 640 


Ser Gln Ser Val Gly Gly Ala Arg Pro Lys Gln Leu Phe Ser Leu Pro 
                645                 650                 655     


Ser Arg Thr Arg Ser Ser Lys Asp Leu Asn Lys Pro Asp Val Pro Asp 
            660                 665                 670         


Thr Ile Glu Ser Glu Pro Ser Thr Ala Asp Thr Val Val Pro Ile Thr 
        675                 680                 685             


Cys Ala Ile Asp Ser Thr Ala Asp Pro Gln Val Ser Phe Asn Ser Asn 
    690                 695                 700                 


Tyr Ile Asp Ile Glu Ser Asn Ser Glu Gly Gly Ser Ser Phe Val Thr 
705                 710                 715                 720 


Ala Asn Glu Asp Ser Val Pro Glu Asn Thr Cys Lys Glu Gly Leu Val 
                725                 730                 735     


Leu Gly Gln Lys Gln Pro Thr Trp Val Pro Asp Ser Glu Ala Pro Asn 
            740                 745                 750         


Cys Met Asn Cys Gln Val Lys Phe Thr Phe Thr Lys Arg Arg His His 
        755                 760                 765             


Cys Arg Ala Cys Gly Lys Val Phe Cys Gly Val Cys Cys Asn Arg Lys 
    770                 775                 780                 


Cys Lys Leu Gln Tyr Leu Glu Lys Glu Ala Arg Val Cys Val Val Cys 
785                 790                 795                 800 


Tyr Glu Thr Ile Ser Lys Ala Gln Ala Phe Glu Arg Met Met Ser Pro 
                805                 810                 815     


Thr Gly Ser Asn Leu Lys Ser Asn His Ser Asp Glu Cys Thr Thr Val 
            820                 825                 830         


Gln Pro Pro Gln Glu Asn Gln Thr Ser Ser Ile Pro Ser Pro Ala Thr 
        835                 840                 845             


Leu Pro Val Ser Ala Leu Lys Gln Pro Gly Val Glu Gly Leu Cys Ser 
    850                 855                 860                 


Lys Glu Gln Lys Arg Val Trp Phe Ala Asp Gly Ile Leu Pro Asn Gly 
865                 870                 875                 880 


Glu Val Ala Asp Thr Thr Lys Leu Ser Ser Gly Ser Lys Arg Cys Ser 
                885                 890                 895     


Glu Asp Phe Ser Pro Leu Ser Pro Asp Val Pro Met Thr Val Asn Thr 
            900                 905                 910         


Val Asp His Ser His Ser Thr Thr Val Glu Lys Pro Asn Asn Glu Thr 
        915                 920                 925             


Gly Asp Ile Thr Arg Asn Glu Ile Ile Gln Ser Pro Ile Ser Gln Val 
    930                 935                 940                 


Pro Ser Val Glu Lys Leu Ser Met Asn Thr Gly Asn Glu Gly Leu Pro 
945                 950                 955                 960 


Thr Ser Gly Ser Phe Thr Leu Asp Asp Asp Val Phe Ala Glu Thr Glu 
                965                 970                 975     


Glu Pro Ser Ser Pro Thr Gly Val Leu Val Asn Ser Asn Leu Pro Ile 
            980                 985                 990         


Ala Ser Ile Ser Asp Tyr Arg Leu  Leu Cys Asp Ile Asn  Lys Tyr Val 
        995                 1000                 1005             


Cys Asn  Lys Ile Ser Leu Leu  Pro Asn Asp Glu Asp  Ser Leu Pro 
    1010                 1015                 1020             


Pro Leu  Leu Val Ala Ser Gly  Glu Lys Gly Ser Val  Pro Val Val 
    1025                 1030                 1035             


Glu Glu  His Pro Ser His Glu  Gln Ile Ile Leu Leu  Leu Glu Gly 
    1040                 1045                 1050             


Glu Gly  Phe His Pro Val Thr  Phe Val Leu Asn Ala  Asn Leu Leu 
    1055                 1060                 1065             


Val Asn  Val Lys Phe Ile Phe  Tyr Ser Ser Asp Lys  Tyr Trp Tyr 
    1070                 1075                 1080             


Phe Ser  Thr Asn Gly Leu His  Gly Leu Gly Gln Ala  Glu Ile Ile 
    1085                 1090                 1095             


Ile Leu  Leu Leu Cys Leu Pro  Asn Glu Asp Thr Ile  Pro Lys Asp 
    1100                 1105                 1110             


Ile Phe  Arg Leu Phe Ile Thr  Ile Tyr Lys Asp Ala  Leu Lys Gly 
    1115                 1120                 1125             


Lys Tyr  Ile Glu Asn Leu Asp  Asn Ile Thr Phe Thr  Glu Ser Phe 
    1130                 1135                 1140             


Leu Ser  Ser Lys Asp His Gly  Gly Phe Leu Phe Ile  Thr Pro Thr 
    1145                 1150                 1155             


Phe Gln  Lys Leu Asp Asp Leu  Ser Leu Pro Ser Asn  Pro Phe Leu 
    1160                 1165                 1170             


Cys Gly  Ile Leu Ile Gln Lys  Leu Glu Ile Pro Trp  Ala Lys Val 
    1175                 1180                 1185             


Phe Pro  Met Arg Leu Met Leu  Arg Leu Gly Ala Glu  Tyr Lys Ala 
    1190                 1195                 1200             


Tyr Pro  Ala Pro Leu Thr Ser  Ile Arg Gly Arg Lys  Pro Leu Phe 
    1205                 1210                 1215             


Gly Glu  Ile Gly His Thr Ile  Met Asn Leu Leu Val  Asp Leu Arg 
    1220                 1225                 1230             


Asn Tyr  Gln Tyr Thr Leu His  Asn Ile Asp Gln Leu  Leu Ile His 
    1235                 1240                 1245             


Met Glu  Met Gly Lys Ser Cys  Ile Lys Ile Pro Arg  Lys Lys Tyr 
    1250                 1255                 1260             


Ser Asp  Val Met Lys Val Leu  Asn Ser Ser Asn Glu  His Val Ile 
    1265                 1270                 1275             


Ser Ile  Gly Ala Ser Phe Ser  Thr Glu Ala Asp Ser  His Leu Val 
    1280                 1285                 1290             


Cys Ile  Gln Asn Asp Gly Ile  Tyr Glu Thr Gln Ala  Asn Ser Ala 
    1295                 1300                 1305             


Thr Gly  His Pro Arg Lys Val  Thr Gly Ala Ser Phe  Val Val Phe 
    1310                 1315                 1320             


Asn Gly  Ala Leu Lys Thr Ser  Ser Gly Phe Leu Ala  Lys Ser Ser 
    1325                 1330                 1335             


Ile Val  Glu Asp Gly Leu Met  Val Gln Ile Thr Pro  Glu Thr Met 
    1340                 1345                 1350             


Asn Gly  Leu Arg Leu Ala Leu  Arg Glu Gln Lys Asp  Phe Lys Ile 
    1355                 1360                 1365             


Thr Cys  Gly Lys Val Asp Ala  Val Asp Leu Arg Glu  Tyr Val Asp 
    1370                 1375                 1380             


Ile Cys  Trp Val Asp Ala Glu  Glu Lys Gly Asn Lys  Gly Val Ile 
    1385                 1390                 1395             


Ser Ser  Val Asp Gly Ile Ser  Leu Gln Gly Phe Pro  Ser Glu Lys 
    1400                 1405                 1410             


Ile Lys  Leu Glu Ala Asp Phe  Glu Thr Asp Glu Lys  Ile Val Lys 
    1415                 1420                 1425             


Cys Thr  Glu Val Phe Tyr Phe  Leu Lys Asp Gln Asp  Leu Ser Ile 
    1430                 1435                 1440             


Leu Ser  Thr Ser Tyr Gln Phe  Ala Lys Glu Ile Ala  Met Ala Cys 
    1445                 1450                 1455             


Ser Ala  Ala Leu Cys Pro His  Leu Lys Thr Leu Lys  Ser Asn Gly 
    1460                 1465                 1470             


Met Asn  Lys Ile Gly Leu Arg  Val Ser Ile Asp Thr  Asp Met Val 
    1475                 1480                 1485             


Glu Phe  Gln Ala Gly Ser Glu  Gly Gln Leu Leu Pro  Gln His Tyr 
    1490                 1495                 1500             


Leu Asn  Asp Leu Asp Ser Ala  Leu Ile Pro Val Ile  His Gly Gly 
    1505                 1510                 1515             


Thr Ser  Asn Ser Ser Leu Pro  Leu Glu Ile Glu Leu  Val Phe Phe 
    1520                 1525                 1530             


Ile Ile  Glu His Leu Phe 
    1535                 


<210>  2934
<211>  1253
<212>  PRT
<213>  homo sapiens

<400>  2934

Met Glu Glu His Ser Tyr Ile Gln Lys Glu Leu Asp Leu Gln Asn Gly 
1               5                   10                  15      


Ser Leu Glu Glu Asp Ser Val Val His Ser Val Glu Asn Asp Ser Gln 
            20                  25                  30          


Asn Met Met Glu Ser Leu Ser Pro Lys Lys Tyr Ser Ser Ser Leu Arg 
        35                  40                  45              


Phe Lys Ala Asn Gly Asp Tyr Ser Gly Ser Tyr Leu Thr Leu Ser Gln 
    50                  55                  60                  


Pro Val Pro Ala Lys Arg Ser Pro Ser Pro Leu Gly Thr Ser Val Arg 
65                  70                  75                  80  


Ser Ser Pro Ser Leu Ala Lys Ile Gln Gly Ser Lys Gln Phe Ser Tyr 
                85                  90                  95      


Asp Gly Thr Asp Lys Asn Ile Pro Met Lys Pro Pro Thr Pro Leu Leu 
            100                 105                 110         


Asn Thr Thr Ser Ser Leu Ser Gly Tyr Pro Leu Gly Arg Ala Asp Phe 
        115                 120                 125             


Asp His Tyr Thr Gly Arg Asp Ser Glu Arg Ala Leu Arg Leu Ser Glu 
    130                 135                 140                 


Lys Pro Pro Tyr Ser Lys Tyr Ser Ser Arg His Lys Ser His Asp Asn 
145                 150                 155                 160 


Val Tyr Ser Leu Gly Gly Leu Glu Gly Arg Lys Ala Ser Gly Ser Leu 
                165                 170                 175     


Leu Ala Met Trp Asn Gly Ser Ser Leu Ser Asp Ala Gly Pro Pro Pro 
            180                 185                 190         


Ile Ser Arg Ser Gly Ala Ala Ser Met Pro Ser Ser Pro Lys Gln Ala 
        195                 200                 205             


Arg Lys Met Ser Ile Gln Asp Ser Leu Ala Leu Gln Pro Lys Leu Thr 
    210                 215                 220                 


Arg His Lys Glu Leu Ala Ser Glu Asn Ile Asn Leu Arg Thr Arg Lys 
225                 230                 235                 240 


Tyr Ser Ser Ser Ser Leu Ser His Met Gly Ala Tyr Ser Arg Ser Leu 
                245                 250                 255     


Pro Arg Leu Tyr Arg Ala Thr Glu Asn Gln Leu Thr Pro Leu Ser Leu 
            260                 265                 270         


Pro Pro Arg Asn Ser Leu Gly Asn Ser Lys Arg Thr Lys Leu Gly Glu 
        275                 280                 285             


Lys Asp Leu Pro His Ser Val Ile Asp Asn Asp Asn Tyr Leu Asn Phe 
    290                 295                 300                 


Ser Ser Leu Ser Ser Gly Ala Leu Pro Tyr Lys Thr Ser Ala Ser Glu 
305                 310                 315                 320 


Gly Asn Pro Tyr Val Ser Ser Thr Leu Ser Val Pro Ala Ser Pro Arg 
                325                 330                 335     


Val Ala Arg Lys Met Leu Leu Ala Ser Thr Ser Ser Cys Ala Ser Asp 
            340                 345                 350         


Asp Phe Asp Gln Ala Ser Tyr Val Gly Thr Asn Pro Ser His Ser Leu 
        355                 360                 365             


Leu Ala Gly Glu Ser Asp Arg Val Phe Ala Thr Arg Arg Asn Phe Ser 
    370                 375                 380                 


Cys Gly Ser Val Glu Phe Asp Glu Ala Asp Leu Glu Ser Leu Arg Gln 
385                 390                 395                 400 


Ala Ser Gly Thr Pro Gln Pro Ala Leu Arg Glu Arg Lys Ser Ser Ile 
                405                 410                 415     


Ser Ser Ile Ser Gly Arg Asp Asp Leu Met Asp Tyr His Arg Arg Gln 
            420                 425                 430         


Arg Glu Glu Arg Leu Arg Glu Gln Glu Met Glu Arg Leu Glu Arg Gln 
        435                 440                 445             


Arg Leu Glu Thr Ile Leu Ser Leu Cys Ala Glu Tyr Thr Lys Pro Asp 
    450                 455                 460                 


Ser Arg Leu Ser Thr Gly Thr Thr Val Glu Asp Val Gln Lys Ile Asn 
465                 470                 475                 480 


Lys Glu Leu Glu Lys Leu Gln Leu Ser Asp Glu Glu Ser Val Phe Glu 
                485                 490                 495     


Glu Ala Leu Met Ser Pro Asp Thr Arg Tyr Arg Cys His Arg Lys Asp 
            500                 505                 510         


Ser Leu Pro Asp Ala Asp Leu Ala Ser Cys Gly Ser Leu Ser Gln Ser 
        515                 520                 525             


Ser Ala Ser Phe Phe Thr Pro Arg Ser Thr Arg Asn Asp Glu Leu Leu 
    530                 535                 540                 


Ser Asp Leu Thr Arg Thr Pro Pro Pro Pro Ser Ser Thr Phe Pro Lys 
545                 550                 555                 560 


Ala Ser Ser Glu Ser Ser Tyr Leu Ser Ile Leu Pro Lys Thr Pro Glu 
                565                 570                 575     


Gly Ile Ser Glu Glu Gln Arg Ser Gln Glu Leu Ala Ala Met Glu Glu 
            580                 585                 590         


Thr Arg Ile Val Ile Leu Asn Asn Leu Glu Glu Leu Lys Gln Lys Ile 
        595                 600                 605             


Lys Asp Ile Asn Asp Gln Met Asp Glu Ser Phe Arg Glu Leu Asp Met 
    610                 615                 620                 


Glu Cys Ala Leu Leu Asp Gly Glu Gln Lys Ser Glu Thr Thr Glu Leu 
625                 630                 635                 640 


Met Lys Glu Lys Glu Ile Leu Asp His Leu Asn Arg Lys Ile Ala Glu 
                645                 650                 655     


Leu Glu Lys Asn Ile Val Gly Glu Lys Thr Lys Glu Lys Val Lys Leu 
            660                 665                 670         


Asp Ala Glu Arg Glu Lys Leu Glu Arg Leu Gln Glu Leu Tyr Ser Glu 
        675                 680                 685             


Gln Lys Thr Gln Leu Asp Asn Cys Pro Glu Ser Met Arg Glu Gln Leu 
    690                 695                 700                 


Gln Gln Gln Leu Lys Arg Asp Ala Asp Leu Leu Asp Val Glu Ser Lys 
705                 710                 715                 720 


His Phe Glu Asp Leu Glu Phe Gln Gln Leu Glu His Glu Ser Arg Leu 
                725                 730                 735     


Asp Glu Glu Lys Glu Asn Leu Thr Gln Gln Leu Leu Arg Glu Val Ala 
            740                 745                 750         


Glu Tyr Gln Arg Asn Ile Val Ser Arg Lys Glu Lys Ile Ser Ala Leu 
        755                 760                 765             


Lys Lys Gln Ala Asn His Ile Val Gln Gln Ala Gln Arg Glu Gln Asp 
    770                 775                 780                 


His Phe Val Lys Glu Lys Asn Asn Leu Ile Met Met Leu Gln Arg Glu 
785                 790                 795                 800 


Lys Glu Asn Leu Cys Asn Leu Glu Lys Lys Tyr Ser Ser Leu Ser Gly 
                805                 810                 815     


Gly Lys Gly Phe Pro Val Asn Pro Asn Thr Leu Lys Glu Gly Tyr Ile 
            820                 825                 830         


Ser Val Asn Glu Ile Asn Glu Pro Cys Gly Asn Ser Thr Asn Leu Ser 
        835                 840                 845             


Pro Ser Thr Gln Phe Pro Ala Asp Ala Asp Ala Val Ala Thr Glu Pro 
    850                 855                 860                 


Ala Thr Ala Val Leu Ala Ser Gln Pro Gln Ser Lys Glu His Phe Arg 
865                 870                 875                 880 


Ser Leu Glu Glu Arg Lys Lys Gln His Lys Glu Gly Leu Tyr Leu Ser 
                885                 890                 895     


Asp Thr Leu Pro Arg Lys Lys Thr Thr Ser Ser Ile Ser Pro His Phe 
            900                 905                 910         


Ser Ser Ala Thr Met Gly Arg Ser Ile Thr Pro Lys Ala His Leu Pro 
        915                 920                 925             


Leu Gly Gln Ser Asn Ser Cys Gly Ser Val Leu Pro Pro Ser Leu Ala 
    930                 935                 940                 


Ala Met Ala Lys Asp Ser Glu Ser Arg Arg Met Leu Arg Gly Tyr Asn 
945                 950                 955                 960 


His Gln Gln Met Ser Glu Gly His Arg Gln Lys Ser Glu Phe Tyr Asn 
                965                 970                 975     


Arg Thr Ala Ser Glu Ser Asn Val Tyr Leu Asn Ser Phe His Tyr Pro 
            980                 985                 990         


Asp His Ser Tyr Lys Asp Gln Ala  Phe Asp Thr Leu Ser  Leu Asp Ser 
        995                 1000                 1005             


Ser Asp  Ser Met Glu Thr Ser  Ile Ser Ala Cys Ser  Pro Asp Asn 
    1010                 1015                 1020             


Ile Ser  Ser Ala Ser Thr Ser  Asn Ile Ala Arg Ile  Glu Glu Met 
    1025                 1030                 1035             


Glu Arg  Leu Leu Lys Gln Ala  His Ala Glu Lys Thr  Arg Leu Leu 
    1040                 1045                 1050             


Glu Ser  Arg Glu Arg Glu Met  Glu Ala Lys Lys Arg  Ala Leu Glu 
    1055                 1060                 1065             


Glu Glu  Lys Arg Arg Arg Glu  Ile Leu Glu Lys Arg  Leu Gln Glu 
    1070                 1075                 1080             


Glu Thr  Ser Gln Arg Gln Lys  Leu Ile Glu Lys Glu  Val Lys Ile 
    1085                 1090                 1095             


Arg Glu  Arg Gln Arg Ala Gln  Ala Arg Pro Leu Thr  Arg Tyr Leu 
    1100                 1105                 1110             


Pro Val  Arg Lys Glu Asp Phe  Asp Leu Arg Ser His  Val Glu Thr 
    1115                 1120                 1125             


Ala Gly  His Asn Ile Asp Thr  Cys Tyr His Val Ser  Ile Thr Glu 
    1130                 1135                 1140             


Lys Thr  Cys Arg Gly Phe Leu  Ile Lys Met Gly Gly  Lys Ile Lys 
    1145                 1150                 1155             


Thr Trp  Lys Lys Arg Trp Phe  Val Phe Asp Arg Asn  Lys Arg Thr 
    1160                 1165                 1170             


Phe Ser  Tyr Tyr Ala Asp Lys  His Glu Thr Lys Leu  Lys Gly Val 
    1175                 1180                 1185             


Ile Tyr  Phe Gln Ala Ile Glu  Glu Val Tyr Tyr Asp  His Leu Lys 
    1190                 1195                 1200             


Asn Ala  Asn Lys Ser Pro Asn  Pro Leu Leu Thr Phe  Ser Val Lys 
    1205                 1210                 1215             


Thr His  Asp Arg Ile Tyr Tyr  Met Val Ala Pro Ser  Pro Glu Ala 
    1220                 1225                 1230             


Met Arg  Ile Trp Met Asp Val  Ile Val Thr Gly Ala  Glu Gly Tyr 
    1235                 1240                 1245             


Thr His  Phe Leu Leu 
    1250             


<210>  2935
<211>  1253
<212>  PRT
<213>  homo sapiens

<400>  2935

Met Glu Glu His Ser Tyr Ile Gln Lys Glu Leu Asp Leu Gln Asn Gly 
1               5                   10                  15      


Ser Leu Glu Glu Asp Ser Val Val His Ser Val Glu Asn Asp Ser Gln 
            20                  25                  30          


Asn Met Met Glu Ser Leu Ser Pro Lys Lys Tyr Ser Ser Ser Leu Arg 
        35                  40                  45              


Phe Lys Ala Asn Gly Asp Tyr Ser Gly Ser Tyr Leu Thr Leu Ser Gln 
    50                  55                  60                  


Pro Val Pro Ala Lys Arg Ser Pro Ser Pro Leu Gly Thr Ser Val Arg 
65                  70                  75                  80  


Ser Ser Pro Ser Leu Ala Lys Ile Gln Gly Ser Lys Gln Phe Ser Tyr 
                85                  90                  95      


Asp Gly Thr Asp Lys Asn Ile Pro Met Lys Pro Pro Thr Pro Leu Leu 
            100                 105                 110         


Asn Thr Thr Ser Ser Leu Ser Gly Tyr Pro Leu Gly Arg Ala Asp Phe 
        115                 120                 125             


Asp His Tyr Thr Gly Arg Asp Ser Glu Arg Ala Leu Arg Leu Ser Glu 
    130                 135                 140                 


Lys Pro Pro Tyr Ser Lys Tyr Ser Ser Arg His Lys Ser His Asp Asn 
145                 150                 155                 160 


Val Tyr Ser Leu Gly Gly Leu Glu Gly Arg Lys Ala Ser Gly Ser Leu 
                165                 170                 175     


Leu Ala Met Trp Asn Gly Ser Ser Leu Ser Asp Ala Gly Pro Pro Pro 
            180                 185                 190         


Ile Ser Arg Ser Gly Ala Ala Ser Met Pro Ser Ser Pro Lys Gln Ala 
        195                 200                 205             


Arg Lys Met Ser Ile Gln Asp Ser Leu Ala Leu Gln Pro Lys Leu Thr 
    210                 215                 220                 


Arg His Lys Glu Leu Ala Ser Glu Asn Ile Asn Leu Arg Thr Arg Lys 
225                 230                 235                 240 


Tyr Ser Ser Ser Ser Leu Ser His Met Gly Ala Tyr Ser Arg Ser Leu 
                245                 250                 255     


Pro Arg Leu Tyr Arg Ala Thr Glu Asn Gln Leu Thr Pro Leu Ser Leu 
            260                 265                 270         


Pro Pro Arg Asn Ser Leu Gly Asn Ser Lys Arg Thr Lys Leu Gly Glu 
        275                 280                 285             


Lys Asp Leu Pro His Ser Val Ile Asp Asn Asp Asn Tyr Leu Asn Phe 
    290                 295                 300                 


Ser Ser Leu Ser Ser Gly Ala Leu Pro Tyr Lys Thr Ser Ala Ser Glu 
305                 310                 315                 320 


Gly Asn Pro Tyr Val Ser Ser Thr Leu Ser Val Pro Ala Ser Pro Arg 
                325                 330                 335     


Val Ala Arg Lys Met Leu Leu Ala Ser Thr Ser Ser Cys Ala Ser Asp 
            340                 345                 350         


Asp Phe Asp Gln Ala Ser Tyr Val Gly Thr Asn Pro Ser His Ser Leu 
        355                 360                 365             


Leu Ala Gly Glu Ser Asp Arg Val Phe Ala Thr Arg Arg Asn Phe Ser 
    370                 375                 380                 


Cys Gly Ser Val Glu Phe Asp Glu Ala Asp Leu Glu Ser Leu Arg Gln 
385                 390                 395                 400 


Ala Ser Gly Thr Pro Gln Pro Ala Leu Arg Glu Arg Lys Ser Ser Ile 
                405                 410                 415     


Ser Ser Ile Ser Gly Arg Asp Asp Leu Met Asp Tyr His Arg Arg Gln 
            420                 425                 430         


Arg Glu Glu Arg Leu Arg Glu Gln Glu Met Glu Arg Leu Glu Arg Gln 
        435                 440                 445             


Arg Leu Glu Thr Ile Leu Ser Leu Cys Ala Glu Tyr Thr Lys Pro Asp 
    450                 455                 460                 


Ser Arg Leu Ser Thr Gly Thr Thr Val Glu Asp Val Gln Lys Ile Asn 
465                 470                 475                 480 


Lys Glu Leu Glu Lys Leu Gln Leu Ser Asp Glu Glu Ser Val Phe Glu 
                485                 490                 495     


Glu Ala Leu Met Ser Pro Asp Thr Arg Tyr Arg Cys His Arg Lys Asp 
            500                 505                 510         


Ser Leu Pro Asp Ala Asp Leu Ala Ser Cys Gly Ser Leu Ser Gln Ser 
        515                 520                 525             


Ser Ala Ser Phe Phe Thr Pro Arg Ser Thr Arg Asn Asp Glu Leu Leu 
    530                 535                 540                 


Ser Asp Leu Thr Arg Thr Pro Pro Pro Pro Ser Ser Thr Phe Pro Lys 
545                 550                 555                 560 


Ala Ser Ser Glu Ser Ser Tyr Leu Ser Ile Leu Pro Lys Thr Pro Glu 
                565                 570                 575     


Gly Ile Ser Glu Glu Gln Arg Ser Gln Glu Leu Ala Ala Met Glu Glu 
            580                 585                 590         


Thr Arg Ile Val Ile Leu Asn Asn Leu Glu Glu Leu Lys Gln Lys Ile 
        595                 600                 605             


Lys Asp Ile Asn Asp Gln Met Asp Glu Ser Phe Arg Glu Leu Asp Met 
    610                 615                 620                 


Glu Cys Ala Leu Leu Asp Gly Glu Gln Lys Ser Glu Thr Thr Glu Leu 
625                 630                 635                 640 


Met Lys Glu Lys Glu Ile Leu Asp His Leu Asn Arg Lys Ile Ala Glu 
                645                 650                 655     


Leu Glu Lys Asn Ile Val Gly Glu Lys Thr Lys Glu Lys Val Lys Leu 
            660                 665                 670         


Asp Ala Glu Arg Glu Lys Leu Glu Arg Leu Gln Glu Leu Tyr Ser Glu 
        675                 680                 685             


Gln Lys Thr Gln Leu Asp Asn Cys Pro Glu Ser Met Arg Glu Gln Leu 
    690                 695                 700                 


Gln Gln Gln Leu Lys Arg Asp Ala Asp Leu Leu Asp Val Glu Ser Lys 
705                 710                 715                 720 


His Phe Glu Asp Leu Glu Phe Gln Gln Leu Glu His Glu Ser Arg Leu 
                725                 730                 735     


Asp Glu Glu Lys Glu Asn Leu Thr Gln Gln Leu Leu Arg Glu Val Ala 
            740                 745                 750         


Glu Tyr Gln Arg Asn Ile Val Ser Arg Lys Glu Lys Ile Ser Ala Leu 
        755                 760                 765             


Lys Lys Gln Ala Asn His Ile Val Gln Gln Ala Gln Arg Glu Gln Asp 
    770                 775                 780                 


His Phe Val Lys Glu Lys Asn Asn Leu Ile Met Met Leu Gln Arg Glu 
785                 790                 795                 800 


Lys Glu Asn Leu Cys Asn Leu Glu Lys Lys Tyr Ser Ser Leu Ser Gly 
                805                 810                 815     


Gly Lys Gly Phe Pro Val Asn Pro Asn Thr Leu Lys Glu Gly Tyr Ile 
            820                 825                 830         


Ser Val Asn Glu Ile Asn Glu Pro Cys Gly Asn Ser Thr Asn Leu Ser 
        835                 840                 845             


Pro Ser Thr Gln Phe Pro Ala Asp Ala Asp Ala Val Ala Thr Glu Pro 
    850                 855                 860                 


Ala Thr Ala Val Leu Ala Ser Gln Pro Gln Ser Lys Glu His Phe Arg 
865                 870                 875                 880 


Ser Leu Glu Glu Arg Lys Lys Gln His Lys Glu Gly Leu Tyr Leu Ser 
                885                 890                 895     


Asp Thr Leu Pro Arg Lys Lys Thr Thr Ser Ser Ile Ser Pro His Phe 
            900                 905                 910         


Ser Ser Ala Thr Met Gly Arg Ser Ile Thr Pro Lys Ala His Leu Pro 
        915                 920                 925             


Leu Gly Gln Ser Asn Ser Cys Gly Ser Val Leu Pro Pro Ser Leu Ala 
    930                 935                 940                 


Ala Met Ala Lys Asp Ser Glu Ser Arg Arg Met Leu Arg Gly Tyr Asn 
945                 950                 955                 960 


His Gln Gln Met Ser Glu Gly His Arg Gln Lys Ser Glu Phe Tyr Asn 
                965                 970                 975     


Arg Thr Ala Ser Glu Ser Asn Val Tyr Leu Asn Ser Phe His Tyr Pro 
            980                 985                 990         


Asp His Ser Tyr Lys Asp Gln Ala  Phe Asp Thr Leu Ser  Leu Asp Ser 
        995                 1000                 1005             


Ser Asp  Ser Met Glu Thr Ser  Ile Ser Ala Cys Ser  Pro Asp Asn 
    1010                 1015                 1020             


Ile Ser  Ser Ala Ser Thr Ser  Asn Ile Ala Arg Ile  Glu Glu Met 
    1025                 1030                 1035             


Glu Arg  Leu Leu Lys Gln Ala  His Ala Glu Lys Thr  Arg Leu Leu 
    1040                 1045                 1050             


Glu Ser  Arg Glu Arg Glu Met  Glu Ala Lys Lys Arg  Ala Leu Glu 
    1055                 1060                 1065             


Glu Glu  Lys Arg Arg Arg Glu  Ile Leu Glu Lys Arg  Leu Gln Glu 
    1070                 1075                 1080             


Glu Thr  Ser Gln Arg Gln Lys  Leu Ile Glu Lys Glu  Val Lys Ile 
    1085                 1090                 1095             


Arg Glu  Arg Gln Arg Ala Gln  Ala Arg Pro Leu Thr  Arg Tyr Leu 
    1100                 1105                 1110             


Pro Val  Arg Lys Glu Asp Phe  Asp Leu Arg Ser His  Val Glu Thr 
    1115                 1120                 1125             


Ala Gly  His Asn Ile Asp Thr  Cys Tyr His Val Ser  Ile Thr Glu 
    1130                 1135                 1140             


Lys Thr  Cys Arg Gly Phe Leu  Ile Lys Met Gly Gly  Lys Ile Lys 
    1145                 1150                 1155             


Thr Trp  Lys Lys Arg Trp Phe  Val Phe Asp Arg Asn  Lys Arg Thr 
    1160                 1165                 1170             


Phe Ser  Tyr Tyr Ala Asp Lys  His Glu Thr Lys Leu  Lys Gly Val 
    1175                 1180                 1185             


Ile Tyr  Phe Gln Ala Ile Glu  Glu Val Tyr Tyr Asp  His Leu Lys 
    1190                 1195                 1200             


Asn Ala  Asn Lys Ser Pro Asn  Pro Leu Leu Thr Phe  Ser Val Lys 
    1205                 1210                 1215             


Thr His  Asp Arg Ile Tyr Tyr  Met Val Ala Pro Ser  Pro Glu Ala 
    1220                 1225                 1230             


Met Arg  Ile Trp Met Asp Val  Ile Val Thr Gly Ala  Glu Gly Tyr 
    1235                 1240                 1245             


Thr His  Phe Leu Leu 
    1250             


<210>  2936
<211>  286
<212>  PRT
<213>  homo sapiens

<400>  2936

Met Arg Leu Leu Pro Arg Leu Leu Leu Leu Leu Leu Leu Val Phe Pro 
1               5                   10                  15      


Ala Thr Val Leu Phe Arg Gly Gly Pro Arg Gly Leu Leu Ala Val Ala 
            20                  25                  30          


Gln Asp Leu Thr Glu Asp Glu Glu Thr Val Glu Asp Ser Ile Ile Glu 
        35                  40                  45              


Asp Glu Asp Asp Glu Ala Glu Val Glu Glu Asp Glu Pro Thr Asp Leu 
    50                  55                  60                  


Val Glu Asp Lys Glu Glu Glu Asp Val Ser Gly Glu Pro Glu Ala Ser 
65                  70                  75                  80  


Pro Ser Ala Asp Thr Thr Ile Leu Phe Val Lys Gly Glu Asp Phe Pro 
                85                  90                  95      


Ala Asn Asn Ile Val Lys Phe Leu Val Gly Phe Thr Asn Lys Gly Thr 
            100                 105                 110         


Glu Asp Phe Ile Val Glu Ser Leu Asp Ala Ser Phe Arg Tyr Pro Gln 
        115                 120                 125             


Asp Tyr Gln Phe Tyr Ile Gln Asn Phe Thr Ala Leu Pro Leu Asn Thr 
    130                 135                 140                 


Val Val Pro Pro Gln Arg Gln Ala Thr Phe Glu Tyr Ser Phe Ile Pro 
145                 150                 155                 160 


Ala Glu Pro Met Gly Gly Arg Pro Phe Gly Leu Val Ile Asn Leu Asn 
                165                 170                 175     


Tyr Lys Asp Leu Asn Gly Asn Val Phe Gln Asp Ala Val Phe Asn Gln 
            180                 185                 190         


Thr Val Thr Val Ile Glu Arg Glu Asp Gly Leu Asp Gly Glu Thr Ile 
        195                 200                 205             


Phe Met Tyr Met Phe Leu Ala Gly Leu Gly Leu Leu Val Ile Val Gly 
    210                 215                 220                 


Leu His Gln Leu Leu Glu Ser Arg Lys Arg Lys Arg Pro Ile Gln Lys 
225                 230                 235                 240 


Val Glu Met Gly Thr Ser Ser Gln Asn Asp Val Asp Met Ser Trp Ile 
                245                 250                 255     


Pro Gln Glu Thr Leu Asn Gln Ile Asn Lys Ala Ser Pro Arg Arg Leu 
            260                 265                 270         


Pro Arg Lys Arg Ala Gln Lys Arg Ser Val Gly Ser Asp Glu 
        275                 280                 285     


<210>  2937
<211>  182
<212>  PRT
<213>  homo sapiens

<400>  2937

Met Arg Ala Ala Tyr Leu Phe Leu Leu Phe Leu Pro Gly Leu Leu Ala 
1               5                   10                  15      


Gln Gly Gln Tyr Asp Leu Asp Pro Leu Pro Pro Phe Pro Asp His Val 
            20                  25                  30          


Gln Tyr Thr His Tyr Ser Asp Gln Ile Asp Asn Pro Asp Tyr Tyr Asp 
        35                  40                  45              


Tyr Gln Glu Val Thr Pro Arg Pro Ser Glu Glu Gln Phe Gln Phe Gln 
    50                  55                  60                  


Ser Gln Gln Gln Val Gln Gln Glu Val Ile Pro Ala Pro Thr Pro Glu 
65                  70                  75                  80  


Pro Gly Asn Ala Glu Leu Glu Pro Thr Glu Pro Gly Pro Leu Asp Cys 
                85                  90                  95      


Arg Glu Glu Gln Tyr Pro Cys Thr Arg Leu Tyr Ser Ile His Arg Pro 
            100                 105                 110         


Cys Lys Gln Cys Leu Asn Glu Val Cys Phe Tyr Ser Leu Arg Arg Val 
        115                 120                 125             


Tyr Val Ile Asn Lys Glu Ile Cys Val Arg Thr Val Cys Ala His Glu 
    130                 135                 140                 


Glu Leu Leu Arg Ala Asp Leu Cys Arg Asp Lys Phe Ser Lys Cys Gly 
145                 150                 155                 160 


Val Met Ala Ser Ser Gly Leu Cys Gln Ser Val Ala Ala Ser Cys Ala 
                165                 170                 175     


Arg Ser Cys Gly Ser Cys 
            180         


<210>  2938
<211>  282
<212>  PRT
<213>  homo sapiens

<400>  2938

Met Asp Arg Thr Leu Glu Ser Leu Arg His Ile Ile Ala Gln Val Leu 
1               5                   10                  15      


Pro His Arg Asp Pro Ala Leu Val Phe Lys Asp Leu Asn Val Val Ser 
            20                  25                  30          


Met Leu Gln Glu Phe Trp Glu Ser Lys Gln Gln Gln Lys Ala Ala Phe 
        35                  40                  45              


Pro Ser Glu Gly Val Val Val Tyr Glu Ser Leu Pro Ala Pro Gly Pro 
    50                  55                  60                  


Pro Phe Val Ser Tyr Val Thr Leu Pro Gly Gly Ser Cys Phe Gly Asn 
65                  70                  75                  80  


Phe Gln Cys Cys Leu Ser Arg Ala Glu Ala Arg Arg Asp Ala Ala Lys 
                85                  90                  95      


Val Ala Leu Ile Asn Ser Leu Phe Asn Glu Leu Pro Ser Arg Arg Ile 
            100                 105                 110         


Thr Lys Glu Phe Ile Met Glu Ser Val Gln Glu Ala Val Ala Ser Thr 
        115                 120                 125             


Ser Gly Thr Leu Asp Asp Ala Asp Asp Pro Ser Thr Ser Val Gly Ala 
    130                 135                 140                 


Tyr His Tyr Met Leu Glu Ser Asn Met Gly Lys Thr Met Leu Glu Phe 
145                 150                 155                 160 


Gln Glu Leu Met Thr Ile Phe Gln Leu Leu His Trp Asn Gly Ser Leu 
                165                 170                 175     


Lys Ala Leu Arg Glu Thr Lys Cys Ser Arg Gln Glu Val Ile Ser Tyr 
            180                 185                 190         


Tyr Ser Gln Tyr Ser Leu Asp Glu Lys Met Arg Ser His Met Ala Leu 
        195                 200                 205             


Asp Trp Ile Met Lys Glu Arg Asp Ser Pro Gly Ile Val Ser Gln Glu 
    210                 215                 220                 


Leu Arg Met Ala Leu Arg Gln Leu Glu Glu Ala Arg Lys Ala Gly Gln 
225                 230                 235                 240 


Glu Leu Arg Phe Tyr Lys Glu Lys Lys Glu Ile Leu Ser Leu Ala Leu 
                245                 250                 255     


Thr Gln Ile Cys Ser Asp Pro Asp Thr Ser Ser Pro Ser Asp Asp Gln 
            260                 265                 270         


Leu Ser Leu Thr Ala Leu Cys Gly Tyr His 
        275                 280         


<210>  2939
<211>  5890
<212>  PRT
<213>  homo sapiens

<400>  2939

Met Glu Lys Glu Glu Thr Thr Arg Glu Leu Leu Leu Pro Asn Trp Gln 
1               5                   10                  15      


Gly Ser Gly Ser His Gly Leu Thr Ile Ala Gln Arg Asp Asp Gly Val 
            20                  25                  30          


Phe Val Gln Glu Val Thr Gln Asn Ser Pro Ala Ala Arg Thr Gly Val 
        35                  40                  45              


Val Lys Glu Gly Asp Gln Ile Val Gly Ala Thr Ile Tyr Phe Asp Asn 
    50                  55                  60                  


Leu Gln Ser Gly Glu Val Thr Gln Leu Leu Asn Thr Met Gly His His 
65                  70                  75                  80  


Thr Val Gly Leu Lys Leu His Arg Lys Gly Asp Arg Ser Pro Glu Pro 
                85                  90                  95      


Gly Gln Thr Trp Thr Arg Glu Val Phe Ser Ser Cys Ser Ser Glu Val 
            100                 105                 110         


Val Leu Ser Gly Asp Asp Glu Glu Tyr Gln Arg Ile Tyr Thr Thr Lys 
        115                 120                 125             


Ile Lys Pro Arg Leu Lys Ser Glu Asp Gly Val Glu Gly Asp Leu Gly 
    130                 135                 140                 


Glu Thr Gln Ser Arg Thr Ile Thr Val Thr Arg Arg Val Thr Ala Tyr 
145                 150                 155                 160 


Thr Val Asp Val Thr Gly Arg Glu Gly Ala Lys Asp Ile Asp Ile Ser 
                165                 170                 175     


Ser Pro Glu Phe Lys Ile Lys Ile Pro Arg His Glu Leu Thr Glu Ile 
            180                 185                 190         


Ser Asn Val Asp Val Glu Thr Gln Ser Gly Lys Thr Val Ile Arg Leu 
        195                 200                 205             


Pro Ser Gly Ser Gly Ala Ala Ser Pro Thr Gly Ser Ala Val Asp Ile 
    210                 215                 220                 


Arg Ala Gly Ala Ile Ser Ala Ser Gly Pro Glu Leu Gln Gly Ala Gly 
225                 230                 235                 240 


His Ser Lys Leu Gln Val Thr Met Pro Gly Ile Lys Val Gly Gly Ser 
                245                 250                 255     


Gly Val Asn Val Asn Ala Lys Gly Leu Asp Leu Gly Gly Arg Gly Gly 
            260                 265                 270         


Val Gln Val Pro Ala Val Asp Ile Ser Ser Ser Leu Gly Gly Arg Ala 
        275                 280                 285             


Val Glu Val Gln Gly Pro Ser Leu Glu Ser Gly Asp His Gly Lys Ile 
    290                 295                 300                 


Lys Phe Pro Thr Met Lys Val Pro Lys Phe Gly Val Ser Thr Gly Arg 
305                 310                 315                 320 


Glu Gly Gln Thr Pro Lys Ala Gly Leu Arg Val Ser Ala Pro Glu Val 
                325                 330                 335     


Ser Val Gly His Lys Gly Gly Lys Pro Gly Leu Thr Ile Gln Ala Pro 
            340                 345                 350         


Gln Leu Glu Val Ser Val Pro Ser Ala Asn Ile Glu Gly Leu Glu Gly 
        355                 360                 365             


Lys Leu Lys Gly Pro Gln Ile Thr Gly Pro Ser Leu Glu Gly Asp Leu 
    370                 375                 380                 


Gly Leu Lys Gly Ala Lys Pro Gln Gly His Ile Gly Val Asp Ala Ser 
385                 390                 395                 400 


Ala Pro Gln Ile Gly Gly Ser Ile Thr Gly Pro Ser Val Glu Val Gln 
                405                 410                 415     


Ala Pro Asp Ile Asp Val Gln Gly Pro Gly Ser Lys Leu Asn Val Pro 
            420                 425                 430         


Lys Met Lys Val Pro Lys Phe Ser Val Ser Gly Ala Lys Gly Glu Glu 
        435                 440                 445             


Thr Gly Ile Asp Val Thr Leu Pro Thr Gly Glu Val Thr Val Pro Gly 
    450                 455                 460                 


Val Ser Gly Asp Val Ser Leu Pro Glu Ile Ala Thr Gly Gly Leu Glu 
465                 470                 475                 480 


Gly Lys Met Lys Gly Thr Lys Val Lys Thr Pro Glu Met Ile Ile Gln 
                485                 490                 495     


Lys Pro Lys Ile Ser Met Gln Asp Val Asp Leu Ser Leu Gly Ser Pro 
            500                 505                 510         


Lys Leu Lys Gly Asp Ile Lys Val Ser Ala Pro Gly Val Gln Gly Asp 
        515                 520                 525             


Val Lys Gly Pro Gln Val Ala Leu Lys Gly Ser Arg Val Asp Ile Glu 
    530                 535                 540                 


Thr Pro Asn Leu Glu Gly Thr Leu Thr Gly Pro Arg Leu Gly Ser Pro 
545                 550                 555                 560 


Ser Gly Lys Thr Gly Thr Cys Arg Ile Ser Met Ser Glu Val Asp Leu 
                565                 570                 575     


Asn Val Ala Ala Pro Lys Val Lys Gly Gly Val Asp Val Thr Leu Pro 
            580                 585                 590         


Arg Val Glu Gly Lys Val Lys Val Pro Glu Val Asp Val Arg Gly Pro 
        595                 600                 605             


Lys Val Asp Val Ser Ala Pro Asp Val Glu Ala His Gly Pro Glu Trp 
    610                 615                 620                 


Asn Leu Lys Met Pro Lys Met Lys Met Pro Thr Phe Ser Thr Pro Gly 
625                 630                 635                 640 


Ala Lys Gly Glu Gly Pro Asp Val His Met Thr Leu Pro Lys Gly Asp 
                645                 650                 655     


Ile Ser Ile Ser Gly Pro Lys Val Asn Val Glu Ala Pro Asp Val Asn 
            660                 665                 670         


Leu Glu Gly Leu Gly Gly Lys Leu Lys Gly Pro Asp Val Lys Leu Pro 
        675                 680                 685             


Asp Met Ser Val Lys Thr Pro Lys Ile Ser Met Pro Asp Val Asp Leu 
    690                 695                 700                 


His Val Lys Gly Thr Lys Val Lys Gly Glu Tyr Asp Val Thr Val Pro 
705                 710                 715                 720 


Lys Leu Glu Gly Glu Leu Lys Gly Pro Lys Val Asp Ile Asp Ala Pro 
                725                 730                 735     


Asp Val Asp Val His Gly Pro Asp Trp His Leu Lys Met Pro Lys Met 
            740                 745                 750         


Lys Met Pro Lys Phe Ser Val Pro Gly Phe Lys Ala Glu Gly Pro Glu 
        755                 760                 765             


Val Asp Val Asn Leu Pro Lys Ala Asp Val Asp Ile Ser Gly Pro Lys 
    770                 775                 780                 


Ile Asp Val Thr Ala Pro Asp Val Ser Ile Glu Glu Pro Glu Gly Lys 
785                 790                 795                 800 


Leu Lys Gly Pro Lys Phe Lys Met Pro Glu Met Asn Ile Lys Val Pro 
                805                 810                 815     


Lys Ile Ser Met Pro Asp Val Asp Leu His Leu Lys Gly Pro Asn Val 
            820                 825                 830         


Lys Gly Glu Tyr Asp Val Thr Met Pro Lys Val Glu Ser Glu Ile Lys 
        835                 840                 845             


Val Pro Asp Val Glu Leu Lys Ser Ala Lys Met Asp Ile Asp Val Pro 
    850                 855                 860                 


Asp Val Glu Val Gln Gly Pro Asp Trp His Leu Lys Met Pro Lys Met 
865                 870                 875                 880 


Lys Met Pro Lys Phe Ser Met Pro Gly Phe Lys Ala Glu Gly Pro Glu 
                885                 890                 895     


Val Asp Val Asn Leu Pro Lys Ala Asp Val Asp Ile Ser Gly Pro Lys 
            900                 905                 910         


Val Gly Val Glu Val Pro Asp Val Asn Ile Glu Gly Pro Glu Gly Lys 
        915                 920                 925             


Leu Lys Gly Pro Lys Phe Lys Met Pro Glu Met Asn Ile Lys Ala Pro 
    930                 935                 940                 


Lys Ile Ser Met Pro Asp Val Asp Leu His Met Lys Gly Pro Lys Val 
945                 950                 955                 960 


Lys Gly Glu Tyr Asp Met Thr Val Pro Lys Leu Glu Gly Asp Leu Lys 
                965                 970                 975     


Gly Pro Lys Val Asp Val Ser Ala Pro Asp Val Glu Met Gln Gly Pro 
            980                 985                 990         


Asp Trp Asn Leu Lys Met Pro Lys  Ile Lys Met Pro Lys  Phe Ser Met 
        995                 1000                 1005             


Pro Ser  Leu Lys Gly Glu Gly  Pro Glu Phe Asp Val  Asn Leu Ser 
    1010                 1015                 1020             


Lys Ala  Asn Val Asp Ile Ser  Ala Pro Lys Val Asp  Thr Asn Ala 
    1025                 1030                 1035             


Pro Asp  Leu Ser Leu Glu Gly  Pro Glu Gly Lys Leu  Lys Gly Pro 
    1040                 1045                 1050             


Lys Phe  Lys Met Pro Glu Met  His Phe Arg Ala Pro  Lys Met Ser 
    1055                 1060                 1065             


Leu Pro  Asp Val Asp Leu Asp  Leu Lys Gly Pro Lys  Met Lys Gly 
    1070                 1075                 1080             


Asn Val  Asp Ile Ser Ala Pro  Lys Ile Glu Gly Glu  Met Gln Val 
    1085                 1090                 1095             


Pro Asp  Val Asp Ile Arg Gly  Pro Lys Val Asp Ile  Lys Ala Pro 
    1100                 1105                 1110             


Asp Val  Glu Gly Gln Gly Leu  Asp Trp Ser Leu Lys  Ile Pro Lys 
    1115                 1120                 1125             


Met Lys  Met Pro Lys Phe Ser  Met Pro Ser Leu Lys  Gly Glu Gly 
    1130                 1135                 1140             


Pro Glu  Val Asp Val Asn Leu  Pro Lys Ala Asp Val  Val Val Ser 
    1145                 1150                 1155             


Gly Pro  Lys Val Asp Ile Glu  Ala Pro Asp Val Ser  Leu Glu Gly 
    1160                 1165                 1170             


Pro Glu  Gly Lys Leu Lys Gly  Pro Lys Phe Lys Met  Pro Glu Met 
    1175                 1180                 1185             


His Phe  Lys Thr Pro Lys Ile  Ser Met Pro Asp Val  Asp Leu His 
    1190                 1195                 1200             


Leu Lys  Gly Pro Lys Val Lys  Gly Asp Val Asp Val  Ser Val Pro 
    1205                 1210                 1215             


Lys Val  Glu Gly Glu Met Lys  Val Pro Asp Val Glu  Ile Lys Gly 
    1220                 1225                 1230             


Pro Lys  Met Asp Ile Asp Ala  Pro Asp Val Glu Val  Gln Gly Pro 
    1235                 1240                 1245             


Asp Trp  His Leu Lys Met Pro  Lys Met Lys Met Pro  Lys Phe Ser 
    1250                 1255                 1260             


Met Pro  Gly Phe Lys Gly Glu  Gly Arg Glu Val Asp  Val Asn Leu 
    1265                 1270                 1275             


Pro Lys  Ala Asp Ile Asp Val  Ser Gly Pro Lys Val  Asp Val Glu 
    1280                 1285                 1290             


Val Pro  Asp Val Ser Leu Glu  Gly Pro Glu Gly Lys  Leu Lys Gly 
    1295                 1300                 1305             


Pro Lys  Phe Lys Met Pro Glu  Met His Phe Lys Ala  Pro Lys Ile 
    1310                 1315                 1320             


Ser Met  Pro Asp Val Asp Leu  Asn Leu Lys Gly Pro  Lys Leu Lys 
    1325                 1330                 1335             


Gly Asp  Val Asp Val Ser Leu  Pro Glu Val Glu Gly  Glu Met Lys 
    1340                 1345                 1350             


Val Pro  Asp Val Asp Ile Lys  Gly Pro Lys Val Asp  Ile Ser Ala 
    1355                 1360                 1365             


Pro Asp  Val Asp Val His Gly  Pro Asp Trp His Leu  Lys Met Pro 
    1370                 1375                 1380             


Lys Val  Lys Met Pro Lys Phe  Ser Met Pro Gly Phe  Lys Gly Glu 
    1385                 1390                 1395             


Gly Pro  Glu Val Asp Val Lys  Leu Pro Lys Ala Asp  Val Asp Val 
    1400                 1405                 1410             


Ser Gly  Pro Lys Met Asp Ala  Glu Val Pro Asp Val  Asn Ile Glu 
    1415                 1420                 1425             


Gly Pro  Asp Ala Lys Leu Lys  Gly Pro Lys Phe Lys  Met Pro Glu 
    1430                 1435                 1440             


Met Ser  Ile Lys Pro Gln Lys  Ile Ser Ile Pro Asp  Val Gly Leu 
    1445                 1450                 1455             


His Leu  Lys Gly Pro Lys Met  Lys Gly Asp Tyr Asp  Val Thr Val 
    1460                 1465                 1470             


Pro Lys  Val Glu Gly Glu Ile  Lys Ala Pro Asp Val  Asp Ile Lys 
    1475                 1480                 1485             


Gly Pro  Lys Val Asp Ile Asn  Ala Pro Asp Val Glu  Val His Gly 
    1490                 1495                 1500             


Pro Asp  Trp His Leu Lys Met  Pro Lys Val Lys Met  Pro Lys Phe 
    1505                 1510                 1515             


Ser Met  Pro Gly Phe Lys Gly  Glu Gly Pro Glu Val  Asp Met Asn 
    1520                 1525                 1530             


Leu Pro  Lys Ala Asp Leu Gly  Val Ser Gly Pro Lys  Val Asp Ile 
    1535                 1540                 1545             


Asp Val  Pro Asp Val Asn Leu  Glu Ala Pro Glu Gly  Lys Leu Lys 
    1550                 1555                 1560             


Gly Pro  Lys Phe Lys Met Pro  Ser Met Asn Ile Gln  Thr His Lys 
    1565                 1570                 1575             


Ile Ser  Met Pro Asp Val Gly  Leu Asn Leu Lys Ala  Pro Lys Leu 
    1580                 1585                 1590             


Lys Thr  Asp Val Asp Val Ser  Leu Pro Lys Val Glu  Gly Asp Leu 
    1595                 1600                 1605             


Lys Gly  Pro Glu Ile Asp Val  Lys Ala Pro Lys Met  Asp Val Asn 
    1610                 1615                 1620             


Val Gly  Asp Ile Asp Ile Glu  Gly Pro Glu Gly Lys  Leu Lys Gly 
    1625                 1630                 1635             


Pro Lys  Phe Lys Met Pro Glu  Met His Phe Lys Ala  Pro Lys Ile 
    1640                 1645                 1650             


Ser Met  Pro Asp Val Asp Leu  His Leu Lys Gly Pro  Lys Val Lys 
    1655                 1660                 1665             


Gly Asp  Met Asp Val Ser Val  Pro Lys Val Glu Gly  Glu Met Lys 
    1670                 1675                 1680             


Val Pro  Asp Val Asp Ile Lys  Gly Pro Lys Val Asp  Ile Asp Ala 
    1685                 1690                 1695             


Pro Asp  Val Glu Val His Asp  Pro Asp Trp His Leu  Lys Met Pro 
    1700                 1705                 1710             


Lys Met  Lys Met Pro Lys Phe  Ser Met Pro Gly Phe  Lys Ala Glu 
    1715                 1720                 1725             


Gly Pro  Glu Val Asp Val Asn  Leu Pro Lys Ala Asp  Ile Asp Val 
    1730                 1735                 1740             


Ser Gly  Pro Ser Val Asp Thr  Asp Ala Pro Asp Leu  Asp Ile Glu 
    1745                 1750                 1755             


Gly Pro  Glu Gly Lys Leu Lys  Gly Ser Lys Phe Lys  Met Pro Lys 
    1760                 1765                 1770             


Leu Asn  Ile Lys Ala Pro Lys  Val Ser Met Pro Asp  Val Asp Leu 
    1775                 1780                 1785             


Asn Leu  Lys Gly Pro Lys Leu  Lys Gly Glu Ile Asp  Ala Ser Val 
    1790                 1795                 1800             


Pro Glu  Leu Glu Gly Asp Leu  Arg Gly Pro Gln Val  Asp Val Lys 
    1805                 1810                 1815             


Gly Pro  Phe Val Glu Ala Glu  Val Pro Asp Val Asp  Leu Glu Cys 
    1820                 1825                 1830             


Pro Asp  Ala Lys Leu Lys Gly  Pro Lys Phe Lys Met  Pro Glu Met 
    1835                 1840                 1845             


His Phe  Lys Ala Pro Lys Ile  Ser Met Pro Asp Val  Asp Leu His 
    1850                 1855                 1860             


Leu Lys  Gly Pro Lys Val Lys  Gly Asp Ala Asp Val  Ser Val Pro 
    1865                 1870                 1875             


Lys Leu  Glu Gly Asp Leu Thr  Gly Pro Ser Val Gly  Val Glu Val 
    1880                 1885                 1890             


Pro Asp  Val Glu Leu Glu Cys  Pro Asp Ala Lys Leu  Lys Gly Pro 
    1895                 1900                 1905             


Lys Phe  Lys Met Pro Asp Met  His Phe Lys Ala Pro  Lys Ile Ser 
    1910                 1915                 1920             


Met Pro  Asp Val Asp Leu His  Leu Lys Gly Pro Lys  Val Lys Gly 
    1925                 1930                 1935             


Asp Val  Asp Val Ser Val Pro  Lys Leu Glu Gly Asp  Leu Thr Gly 
    1940                 1945                 1950             


Pro Ser  Val Gly Val Glu Val  Pro Asp Val Glu Leu  Glu Cys Pro 
    1955                 1960                 1965             


Asp Ala  Lys Leu Lys Gly Pro  Lys Phe Lys Met Pro  Glu Met His 
    1970                 1975                 1980             


Phe Lys  Thr Pro Lys Ile Ser  Met Pro Asp Val Asp  Leu His Leu 
    1985                 1990                 1995             


Lys Gly  Pro Lys Val Lys Gly  Asp Met Asp Val Ser  Val Pro Lys 
    2000                 2005                 2010             


Val Glu  Gly Glu Met Lys Val  Pro Asp Val Asp Ile  Lys Gly Pro 
    2015                 2020                 2025             


Lys Met  Asp Ile Asp Ala Pro  Asp Val Asp Val His  Gly Pro Asp 
    2030                 2035                 2040             


Trp His  Leu Lys Met Pro Lys  Met Lys Met Pro Lys  Phe Ser Met 
    2045                 2050                 2055             


Pro Gly  Phe Lys Ala Glu Gly  Pro Glu Val Asp Val  Asn Leu Pro 
    2060                 2065                 2070             


Lys Ala  Asp Val Val Val Ser  Gly Pro Lys Val Asp  Val Glu Val 
    2075                 2080                 2085             


Pro Asp  Val Ser Leu Glu Gly  Pro Glu Gly Lys Leu  Lys Gly Pro 
    2090                 2095                 2100             


Lys Leu  Lys Met Pro Glu Met  His Phe Lys Ala Pro  Lys Ile Ser 
    2105                 2110                 2115             


Met Pro  Asp Val Asp Leu His  Leu Lys Gly Pro Lys  Val Lys Gly 
    2120                 2125                 2130             


Asp Val  Asp Val Ser Leu Pro  Lys Leu Glu Gly Asp  Leu Thr Gly 
    2135                 2140                 2145             


Pro Ser  Val Asp Val Glu Val  Pro Asp Val Glu Leu  Glu Cys Pro 
    2150                 2155                 2160             


Asp Ala  Lys Leu Lys Gly Pro  Lys Phe Lys Met Pro  Glu Met His 
    2165                 2170                 2175             


Phe Lys  Thr Pro Lys Ile Ser  Met Pro Asp Val Asn  Leu Asn Leu 
    2180                 2185                 2190             


Lys Gly  Pro Lys Val Lys Gly  Asp Met Asp Val Ser  Val Pro Lys 
    2195                 2200                 2205             


Val Glu  Gly Glu Met Lys Val  Pro Asp Val Asp Ile  Arg Gly Pro 
    2210                 2215                 2220             


Lys Val  Asp Ile Asp Ala Pro  Asp Val Asp Val His  Gly Pro Asp 
    2225                 2230                 2235             


Trp His  Leu Lys Met Pro Lys  Met Lys Met Pro Lys  Phe Ser Met 
    2240                 2245                 2250             


Pro Gly  Phe Lys Gly Glu Gly  Pro Glu Val Asp Val  Asn Leu Pro 
    2255                 2260                 2265             


Lys Ala  Asp Val Asp Val Ser  Gly Pro Lys Val Asp  Val Glu Val 
    2270                 2275                 2280             


Pro Asp  Val Ser Leu Glu Gly  Pro Glu Gly Lys Leu  Lys Gly Pro 
    2285                 2290                 2295             


Lys Phe  Lys Met Pro Glu Met  His Phe Lys Thr Pro  Lys Ile Ser 
    2300                 2305                 2310             


Met Pro  Asp Val Asp Phe Asn  Leu Lys Gly Pro Lys  Ile Lys Gly 
    2315                 2320                 2325             


Asp Val  Asp Val Ser Ala Pro  Lys Leu Glu Gly Glu  Leu Lys Gly 
    2330                 2335                 2340             


Pro Glu  Leu Asp Val Lys Gly  Pro Lys Leu Asp Ala  Asp Met Pro 
    2345                 2350                 2355             


Glu Val  Ala Val Glu Gly Pro  Asn Gly Lys Trp Lys  Thr Pro Lys 
    2360                 2365                 2370             


Phe Lys  Met Pro Asp Met His  Phe Lys Ala Pro Lys  Ile Ser Met 
    2375                 2380                 2385             


Pro Asp  Leu Asp Leu His Leu  Lys Ser Pro Lys Ala  Lys Gly Glu 
    2390                 2395                 2400             


Val Asp  Val Asp Val Pro Lys  Leu Glu Gly Asp Leu  Lys Gly Pro 
    2405                 2410                 2415             


His Val  Asp Val Ser Gly Pro  Asp Ile Asp Ile Glu  Gly Pro Glu 
    2420                 2425                 2430             


Gly Lys  Leu Lys Gly Pro Lys  Phe Lys Met Pro Asp  Met His Phe 
    2435                 2440                 2445             


Lys Ala  Pro Asn Ile Ser Met  Pro Asp Val Asp Leu  Asn Leu Lys 
    2450                 2455                 2460             


Gly Pro  Lys Ile Lys Gly Asp  Val Asp Val Ser Val  Pro Glu Val 
    2465                 2470                 2475             


Glu Gly  Lys Leu Glu Val Pro  Asp Met Asn Ile Arg  Gly Pro Lys 
    2480                 2485                 2490             


Val Asp  Val Asn Ala Pro Asp  Val Gln Ala Pro Asp  Trp His Leu 
    2495                 2500                 2505             


Lys Met  Pro Lys Met Lys Met  Pro Lys Phe Ser Met  Pro Gly Phe 
    2510                 2515                 2520             


Lys Ala  Glu Gly Pro Glu Val  Asp Val Asn Leu Pro  Lys Ala Asp 
    2525                 2530                 2535             


Val Asp  Ile Ser Gly Pro Lys  Val Asp Ile Glu Gly  Pro Asp Val 
    2540                 2545                 2550             


Asn Ile  Glu Gly Pro Glu Gly  Lys Leu Lys Gly Pro  Lys Leu Lys 
    2555                 2560                 2565             


Met Pro  Glu Met Asn Ile Lys  Ala Pro Lys Ile Ser  Met Pro Asp 
    2570                 2575                 2580             


Phe Asp  Leu His Leu Lys Gly  Pro Lys Val Lys Gly  Asp Val Asp 
    2585                 2590                 2595             


Val Ser  Leu Pro Lys Val Glu  Gly Asp Leu Lys Gly  Pro Glu Val 
    2600                 2605                 2610             


Asp Ile  Lys Gly Pro Lys Val  Asp Ile Asn Ala Pro  Asp Val Gly 
    2615                 2620                 2625             


Val Gln  Gly Pro Asp Trp His  Leu Lys Met Pro Lys  Val Lys Met 
    2630                 2635                 2640             


Pro Lys  Phe Ser Met Pro Gly  Phe Lys Gly Glu Gly  Pro Asp Gly 
    2645                 2650                 2655             


Asp Val  Lys Leu Pro Lys Ala  Asp Ile Asp Val Ser  Gly Pro Lys 
    2660                 2665                 2670             


Val Asp  Ile Glu Gly Pro Asp  Val Asn Ile Glu Gly  Pro Glu Gly 
    2675                 2680                 2685             


Lys Leu  Lys Gly Pro Lys Phe  Lys Met Pro Glu Met  Asn Ile Lys 
    2690                 2695                 2700             


Ala Pro  Lys Ile Ser Met Pro  Asp Ile Asp Leu Asn  Leu Lys Gly 
    2705                 2710                 2715             


Pro Lys  Val Lys Gly Asp Val  Asp Val Ser Leu Pro  Lys Val Glu 
    2720                 2725                 2730             


Gly Asp  Leu Lys Gly Pro Glu  Val Asp Ile Lys Gly  Pro Lys Val 
    2735                 2740                 2745             


Asp Ile  Asp Ala Pro Asp Val  Asp Val His Gly Pro  Asp Trp His 
    2750                 2755                 2760             


Leu Lys  Met Pro Lys Ile Lys  Met Pro Lys Ile Ser  Met Pro Gly 
    2765                 2770                 2775             


Phe Lys  Gly Glu Gly Pro Asp  Val Asp Val Asn Leu  Pro Lys Ala 
    2780                 2785                 2790             


Asp Ile  Asp Val Ser Gly Pro  Lys Val Asp Val Glu  Cys Pro Asp 
    2795                 2800                 2805             


Val Asn  Ile Glu Gly Pro Glu  Gly Lys Trp Lys Ser  Pro Lys Phe 
    2810                 2815                 2820             


Lys Met  Pro Glu Met His Phe  Lys Thr Pro Lys Ile  Ser Met Pro 
    2825                 2830                 2835             


Asp Ile  Asp Leu Asn Leu Thr  Gly Pro Lys Ile Lys  Gly Asp Val 
    2840                 2845                 2850             


Asp Val  Thr Gly Pro Lys Val  Glu Gly Asp Leu Lys  Gly Pro Glu 
    2855                 2860                 2865             


Val Asp  Leu Lys Gly Pro Lys  Val Asp Ile Asp Val  Pro Asp Val 
    2870                 2875                 2880             


Asn Val  Gln Gly Pro Asp Trp  His Leu Lys Met Pro  Lys Met Lys 
    2885                 2890                 2895             


Met Pro  Lys Phe Ser Met Pro  Gly Phe Lys Ala Glu  Gly Pro Glu 
    2900                 2905                 2910             


Val Asp  Val Asn Leu Pro Lys  Ala Asp Val Asp Val  Ser Gly Pro 
    2915                 2920                 2925             


Lys Val  Asp Val Glu Gly Pro  Asp Val Asn Ile Glu  Gly Pro Glu 
    2930                 2935                 2940             


Gly Lys  Leu Lys Gly Pro Lys  Phe Lys Met Pro Glu  Met Asn Ile 
    2945                 2950                 2955             


Lys Ala  Pro Lys Ile Pro Met  Pro Asp Phe Asp Leu  His Leu Lys 
    2960                 2965                 2970             


Gly Pro  Lys Val Lys Gly Asp  Val Asp Ile Ser Leu  Pro Lys Val 
    2975                 2980                 2985             


Glu Gly  Asp Leu Lys Gly Pro  Glu Val Asp Ile Arg  Gly Pro Gln 
    2990                 2995                 3000             


Val Asp  Ile Asp Val Pro Asp  Val Gly Val Gln Gly  Pro Asp Trp 
    3005                 3010                 3015             


His Leu  Lys Met Pro Lys Val  Lys Met Pro Lys Phe  Ser Met Pro 
    3020                 3025                 3030             


Gly Phe  Lys Gly Glu Gly Pro  Asp Val Asp Val Asn  Leu Pro Lys 
    3035                 3040                 3045             


Ala Asp  Leu Asp Val Ser Gly  Pro Lys Val Asp Ile  Asp Val Pro 
    3050                 3055                 3060             


Asp Val  Asn Ile Glu Gly Pro  Glu Gly Lys Leu Lys  Gly Pro Lys 
    3065                 3070                 3075             


Phe Lys  Met Pro Glu Met Asn  Ile Lys Ala Pro Lys  Ile Ser Met 
    3080                 3085                 3090             


Pro Asp  Ile Asp Leu Asn Leu  Lys Gly Pro Lys Val  Lys Gly Asp 
    3095                 3100                 3105             


Met Asp  Val Ser Leu Pro Lys  Val Glu Gly Asp Met  Lys Val Pro 
    3110                 3115                 3120             


Asp Val  Asp Ile Lys Gly Pro  Lys Val Asp Ile Asn  Ala Pro Asp 
    3125                 3130                 3135             


Val Asp  Val Gln Gly Pro Asp  Trp His Leu Lys Met  Pro Lys Ile 
    3140                 3145                 3150             


Lys Met  Pro Lys Ile Ser Met  Pro Gly Phe Lys Gly  Glu Gly Pro 
    3155                 3160                 3165             


Glu Val  Asp Val Asn Leu Pro  Lys Ala Asp Leu Asp  Val Ser Gly 
    3170                 3175                 3180             


Pro Lys  Val Asp Val Asp Val  Pro Asp Val Asn Ile  Glu Gly Pro 
    3185                 3190                 3195             


Asp Ala  Lys Leu Lys Gly Pro  Lys Phe Lys Met Pro  Glu Met Asn 
    3200                 3205                 3210             


Ile Lys  Ala Pro Lys Ile Ser  Met Pro Asp Leu Asp  Leu Asn Leu 
    3215                 3220                 3225             


Lys Gly  Pro Lys Met Lys Gly  Glu Val Asp Val Ser  Leu Ala Asn 
    3230                 3235                 3240             


Val Glu  Gly Asp Leu Lys Gly  Pro Ala Leu Asp Ile  Lys Gly Pro 
    3245                 3250                 3255             


Lys Ile  Asp Val Asp Ala Pro  Asp Ile Asp Ile His  Gly Pro Asp 
    3260                 3265                 3270             


Ala Lys  Leu Lys Gly Pro Lys  Leu Lys Met Pro Asp  Met His Val 
    3275                 3280                 3285             


Asn Met  Pro Lys Ile Ser Met  Pro Glu Ile Asp Leu  Asn Leu Lys 
    3290                 3295                 3300             


Gly Ser  Lys Leu Lys Gly Asp  Val Asp Val Ser Gly  Pro Lys Leu 
    3305                 3310                 3315             


Glu Gly  Asp Ile Lys Ala Pro  Ser Leu Asp Ile Lys  Gly Pro Glu 
    3320                 3325                 3330             


Val Asp  Val Ser Gly Pro Lys  Leu Asn Ile Glu Gly  Lys Ser Lys 
    3335                 3340                 3345             


Lys Ser  Arg Phe Lys Leu Pro  Lys Phe Asn Phe Ser  Gly Ser Lys 
    3350                 3355                 3360             


Val Gln  Thr Pro Glu Val Asp  Val Lys Gly Lys Lys  Pro Asp Ile 
    3365                 3370                 3375             


Asp Ile  Thr Gly Pro Lys Val  Asp Ile Asn Ala Pro  Asp Val Glu 
    3380                 3385                 3390             


Val Gln  Gly Lys Val Lys Gly  Ser Lys Phe Lys Met  Pro Phe Leu 
    3395                 3400                 3405             


Ser Ile  Ser Ser Pro Lys Val  Ser Met Pro Asp Val  Glu Leu Asn 
    3410                 3415                 3420             


Leu Lys  Ser Pro Lys Val Lys  Gly Asp Leu Asp Ile  Ala Gly Pro 
    3425                 3430                 3435             


Asn Leu  Glu Gly Asp Phe Lys  Gly Pro Lys Val Asp  Ile Lys Ala 
    3440                 3445                 3450             


Pro Glu  Val Asn Leu Asn Ala  Pro Asp Val Asp Val  His Gly Pro 
    3455                 3460                 3465             


Asp Trp  Asn Leu Lys Met Pro  Lys Met Lys Met Pro  Lys Phe Ser 
    3470                 3475                 3480             


Val Ser  Gly Leu Lys Ala Glu  Gly Pro Asp Val Ala  Val Asp Leu 
    3485                 3490                 3495             


Pro Lys  Gly Asp Ile Asn Ile  Glu Gly Pro Ser Met  Asn Ile Glu 
    3500                 3505                 3510             


Gly Pro  Asp Leu Asn Val Glu  Gly Pro Glu Gly Gly  Leu Lys Gly 
    3515                 3520                 3525             


Pro Lys  Phe Lys Met Pro Asp  Met Asn Ile Lys Ala  Pro Lys Ile 
    3530                 3535                 3540             


Ser Met  Pro Asp Ile Asp Leu  Asn Leu Lys Gly Pro  Lys Val Lys 
    3545                 3550                 3555             


Gly Asp  Val Asp Ile Ser Leu  Pro Lys Leu Glu Gly  Asp Leu Lys 
    3560                 3565                 3570             


Gly Pro  Glu Val Asp Ile Lys  Gly Pro Lys Val Asp  Ile Asn Ala 
    3575                 3580                 3585             


Pro Asp  Val Asp Val His Gly  Pro Asp Trp His Leu  Lys Met Pro 
    3590                 3595                 3600             


Lys Val  Lys Met Pro Lys Phe  Ser Met Pro Gly Phe  Lys Gly Glu 
    3605                 3610                 3615             


Gly Pro  Glu Val Asp Val Thr  Leu Pro Lys Ala Asp  Ile Asp Ile 
    3620                 3625                 3630             


Ser Gly  Pro Asn Val Asp Val  Asp Val Pro Asp Val  Asn Ile Glu 
    3635                 3640                 3645             


Gly Pro  Asp Ala Lys Leu Lys  Gly Pro Lys Phe Lys  Met Pro Glu 
    3650                 3655                 3660             


Met Asn  Ile Lys Ala Pro Lys  Ile Ser Met Pro Asp  Phe Asp Leu 
    3665                 3670                 3675             


Asn Leu  Lys Gly Pro Lys Met  Lys Gly Asp Val Val  Val Ser Leu 
    3680                 3685                 3690             


Pro Lys  Val Glu Gly Asp Leu  Lys Gly Pro Glu Val  Asp Ile Lys 
    3695                 3700                 3705             


Gly Pro  Lys Val Asp Ile Asp  Thr Pro Asp Ile Asn  Ile Glu Gly 
    3710                 3715                 3720             


Ser Glu  Gly Lys Phe Lys Gly  Pro Lys Phe Lys Ile  Pro Glu Met 
    3725                 3730                 3735             


His Leu  Lys Ala Pro Lys Ile  Ser Met Pro Asp Ile  Asp Leu Asn 
    3740                 3745                 3750             


Leu Lys  Gly Pro Lys Val Lys  Gly Asp Val Asp Val  Ser Leu Pro 
    3755                 3760                 3765             


Lys Met  Glu Gly Asp Leu Lys  Gly Pro Glu Val Asp  Ile Lys Gly 
    3770                 3775                 3780             


Pro Lys  Val Asp Ile Asn Ala  Pro Asp Val Asp Val  Gln Gly Pro 
    3785                 3790                 3795             


Asp Trp  His Leu Lys Met Pro  Lys Val Lys Met Pro  Lys Phe Ser 
    3800                 3805                 3810             


Met Pro  Gly Phe Lys Gly Glu  Gly Pro Asp Val Asp  Val Asn Leu 
    3815                 3820                 3825             


Pro Lys  Ala Asp Leu Asp Val  Ser Gly Pro Lys Val  Asp Ile Asp 
    3830                 3835                 3840             


Val Pro  Asp Val Asn Ile Glu  Gly Pro Glu Gly Lys  Leu Lys Gly 
    3845                 3850                 3855             


Pro Lys  Phe Lys Met Pro Glu  Met Asn Ile Lys Ala  Pro Lys Ile 
    3860                 3865                 3870             


Ser Met  Pro Asp Ile Asp Leu  Asn Leu Lys Gly Pro  Lys Val Lys 
    3875                 3880                 3885             


Gly Asp  Met Asp Val Ser Leu  Pro Lys Val Glu Gly  Asp Met Gln 
    3890                 3895                 3900             


Val Pro  Asp Leu Asp Ile Lys  Gly Pro Lys Val Asp  Ile Asn Ala 
    3905                 3910                 3915             


Pro Asp  Val Asp Val Arg Gly  Pro Asp Trp His Leu  Lys Met Pro 
    3920                 3925                 3930             


Lys Ile  Lys Met Pro Lys Ile  Ser Met Pro Gly Phe  Lys Gly Glu 
    3935                 3940                 3945             


Gly Pro  Glu Val Asp Val Asn  Leu Pro Lys Ala Asp  Leu Asp Val 
    3950                 3955                 3960             


Ser Gly  Pro Lys Val Asp Val  Asp Val Pro Asp Val  Asn Ile Glu 
    3965                 3970                 3975             


Gly Pro  Asp Ala Lys Leu Lys  Gly Pro Lys Phe Lys  Met Pro Glu 
    3980                 3985                 3990             


Met Asn  Ile Lys Ala Pro Lys  Ile Ser Met Pro Asp  Phe Asp Leu 
    3995                 4000                 4005             


His Leu  Lys Gly Pro Lys Val  Lys Gly Asp Val Asp  Val Ser Leu 
    4010                 4015                 4020             


Pro Lys  Met Glu Gly Asp Leu  Lys Ala Pro Glu Val  Asp Ile Lys 
    4025                 4030                 4035             


Gly Pro  Lys Val Asp Ile Asp  Ala Pro Asp Val Asp  Val His Gly 
    4040                 4045                 4050             


Pro Asp  Trp His Leu Lys Met  Pro Lys Val Lys Met  Pro Lys Phe 
    4055                 4060                 4065             


Ser Met  Pro Gly Phe Lys Gly  Glu Gly Pro Glu Val  Asp Val Asn 
    4070                 4075                 4080             


Leu Pro  Lys Ala Asp Ile Asp  Val Ser Gly Pro Lys  Val Asp Ile 
    4085                 4090                 4095             


Asp Thr  Pro Asp Ile Asp Ile  His Gly Pro Glu Gly  Lys Leu Lys 
    4100                 4105                 4110             


Gly Pro  Lys Phe Lys Met Pro  Asp Leu His Leu Lys  Ala Pro Lys 
    4115                 4120                 4125             


Ile Ser  Met Pro Glu Val Asp  Leu Asn Leu Lys Gly  Pro Lys Met 
    4130                 4135                 4140             


Lys Gly  Asp Val Asp Val Ser  Leu Pro Lys Val Glu  Gly Asp Leu 
    4145                 4150                 4155             


Lys Gly  Pro Glu Val Asp Ile  Lys Gly Pro Lys Val  Asp Ile Asp 
    4160                 4165                 4170             


Val Pro  Asp Val Asp Val Gln  Gly Pro Asp Trp His  Leu Lys Met 
    4175                 4180                 4185             


Pro Lys  Val Lys Met Pro Lys  Phe Ser Met Pro Gly  Phe Lys Gly 
    4190                 4195                 4200             


Glu Gly  Pro Asp Val Asp Val  Asn Leu Pro Lys Ala  Asp Leu Asp 
    4205                 4210                 4215             


Val Ser  Gly Pro Lys Val Asp  Ile Asp Val Pro Asp  Val Asn Ile 
    4220                 4225                 4230             


Glu Gly  Pro Asp Ala Lys Leu  Lys Gly Pro Lys Phe  Lys Met Pro 
    4235                 4240                 4245             


Glu Met  Asn Ile Lys Ala Pro  Lys Ile Ser Met Pro  Asp Phe Asp 
    4250                 4255                 4260             


Leu His  Leu Lys Gly Pro Lys  Val Lys Gly Asp Val  Asp Val Ser 
    4265                 4270                 4275             


Leu Pro  Lys Val Glu Gly Asp  Leu Lys Gly Pro Glu  Val Asp Ile 
    4280                 4285                 4290             


Lys Gly  Pro Lys Val Asp Ile  Asp Ala Pro Asp Val  Asp Val His 
    4295                 4300                 4305             


Gly Pro  Asp Trp His Leu Lys  Met Pro Lys Val Lys  Met Pro Lys 
    4310                 4315                 4320             


Phe Ser  Met Pro Gly Phe Lys  Gly Glu Gly Pro Asp  Val Asp Val 
    4325                 4330                 4335             


Thr Leu  Pro Lys Ala Asp Ile  Glu Ile Ser Gly Pro  Lys Val Asp 
    4340                 4345                 4350             


Ile Asp  Ala Pro Asp Val Ser  Ile Glu Gly Pro Asp  Ala Lys Leu 
    4355                 4360                 4365             


Lys Gly  Pro Lys Phe Lys Met  Pro Glu Met Asn Ile  Lys Ala Pro 
    4370                 4375                 4380             


Lys Ile  Ser Met Pro Asp Ile  Asp Phe Asn Leu Lys  Gly Pro Lys 
    4385                 4390                 4395             


Val Lys  Gly Asp Val Asp Val  Ser Leu Pro Lys Val  Glu Gly Asp 
    4400                 4405                 4410             


Leu Lys  Gly Pro Glu Ile Asp  Ile Lys Gly Pro Ser  Leu Asp Ile 
    4415                 4420                 4425             


Asp Thr  Pro Asp Val Asn Ile  Glu Gly Pro Glu Gly  Lys Leu Lys 
    4430                 4435                 4440             


Gly Pro  Lys Phe Lys Met Pro  Glu Met Asn Ile Lys  Ala Pro Lys 
    4445                 4450                 4455             


Ile Ser  Met Pro Asp Phe Asp  Leu His Leu Lys Gly  Pro Lys Val 
    4460                 4465                 4470             


Lys Gly  Asp Val Asp Val Ser  Leu Pro Lys Val Glu  Ser Asp Leu 
    4475                 4480                 4485             


Lys Gly  Pro Glu Val Asp Ile  Glu Gly Pro Glu Gly  Lys Leu Lys 
    4490                 4495                 4500             


Gly Pro  Lys Phe Lys Met Pro  Asp Val His Phe Lys  Ser Pro Gln 
    4505                 4510                 4515             


Ile Ser  Met Ser Asp Ile Asp  Leu Asn Leu Lys Gly  Pro Lys Ile 
    4520                 4525                 4530             


Lys Gly  Asp Met Asp Ile Ser  Val Pro Lys Leu Glu  Gly Asp Leu 
    4535                 4540                 4545             


Lys Gly  Pro Lys Val Asp Val  Lys Gly Pro Lys Val  Gly Ile Asp 
    4550                 4555                 4560             


Thr Pro  Asp Ile Asp Ile His  Gly Pro Glu Gly Lys  Leu Lys Gly 
    4565                 4570                 4575             


Pro Lys  Phe Lys Met Pro Asp  Leu His Leu Lys Ala  Pro Lys Ile 
    4580                 4585                 4590             


Ser Met  Pro Glu Val Asp Leu  Asn Leu Lys Gly Pro  Lys Val Lys 
    4595                 4600                 4605             


Gly Asp  Met Asp Ile Ser Leu  Pro Lys Val Glu Gly  Asp Leu Lys 
    4610                 4615                 4620             


Gly Pro  Glu Val Asp Ile Arg  Asp Pro Lys Val Asp  Ile Asp Val 
    4625                 4630                 4635             


Pro Asp  Val Asp Val Gln Gly  Pro Asp Trp His Leu  Lys Met Pro 
    4640                 4645                 4650             


Lys Val  Lys Met Pro Lys Phe  Ser Met Pro Gly Phe  Lys Gly Glu 
    4655                 4660                 4665             


Gly Pro  Asp Val Asp Val Asn  Leu Pro Lys Ala Asp  Ile Asp Val 
    4670                 4675                 4680             


Ser Gly  Pro Lys Val Asp Val  Asp Val Pro Asp Val  Asn Ile Glu 
    4685                 4690                 4695             


Gly Pro  Asp Ala Lys Leu Lys  Gly Pro Lys Phe Lys  Met Pro Glu 
    4700                 4705                 4710             


Met Ser  Ile Lys Ala Pro Lys  Ile Ser Met Pro Asp  Ile Asp Leu 
    4715                 4720                 4725             


Asn Leu  Lys Gly Pro Lys Val  Lys Gly Asp Val Asp  Val Thr Leu 
    4730                 4735                 4740             


Pro Lys  Val Glu Gly Asp Leu  Lys Gly Pro Glu Ala  Asp Ile Lys 
    4745                 4750                 4755             


Gly Pro  Lys Val Asp Ile Asn  Thr Pro Asp Val Asp  Val His Gly 
    4760                 4765                 4770             


Pro Asp  Trp His Leu Lys Met  Pro Lys Val Lys Met  Pro Lys Phe 
    4775                 4780                 4785             


Ser Met  Pro Gly Phe Lys Gly  Glu Gly Pro Asp Val  Asp Val Ser 
    4790                 4795                 4800             


Leu Pro  Lys Ala Asp Ile Asp  Val Ser Gly Pro Lys  Val Asp Val 
    4805                 4810                 4815             


Asp Ile  Pro Asp Val Asn Ile  Glu Gly Pro Asp Ala  Lys Leu Lys 
    4820                 4825                 4830             


Gly Pro  Lys Phe Lys Met Pro  Glu Ile Asn Ile Lys  Ala Pro Lys 
    4835                 4840                 4845             


Ile Ser  Ile Pro Asp Val Asp  Leu Asp Leu Lys Gly  Pro Lys Val 
    4850                 4855                 4860             


Lys Gly  Asp Phe Asp Val Ser  Val Pro Lys Val Glu  Gly Thr Leu 
    4865                 4870                 4875             


Lys Gly  Pro Glu Val Asp Leu  Lys Gly Pro Arg Leu  Asp Phe Glu 
    4880                 4885                 4890             


Gly Pro  Asp Ala Lys Leu Ser  Gly Pro Ser Leu Lys  Met Pro Ser 
    4895                 4900                 4905             


Leu Glu  Ile Ser Ala Pro Lys  Val Thr Ala Pro Asp  Val Asp Leu 
    4910                 4915                 4920             


His Leu  Lys Ala Pro Lys Ile  Gly Phe Ser Gly Pro  Lys Leu Glu 
    4925                 4930                 4935             


Gly Gly  Glu Val Asp Leu Lys  Gly Pro Lys Val Glu  Ala Pro Ser 
    4940                 4945                 4950             


Leu Asp  Val His Met Asp Ser  Pro Asp Ile Asn Ile  Glu Gly Pro 
    4955                 4960                 4965             


Asp Val  Lys Ile Pro Lys Phe  Lys Lys Pro Lys Phe  Gly Phe Gly 
    4970                 4975                 4980             


Ala Lys  Ser Pro Lys Ala Asp  Ile Lys Ser Pro Ser  Leu Asp Val 
    4985                 4990                 4995             


Thr Val  Pro Glu Ala Glu Leu  Asn Leu Glu Thr Pro  Glu Ile Ser 
    5000                 5005                 5010             


Val Gly  Gly Lys Gly Lys Lys  Ser Lys Phe Lys Met  Pro Lys Ile 
    5015                 5020                 5025             


His Met  Ser Gly Pro Lys Ile  Lys Ala Lys Lys Gln  Gly Phe Asp 
    5030                 5035                 5040             


Leu Asn  Val Pro Gly Gly Glu  Ile Asp Ala Ser Leu  Lys Ala Pro 
    5045                 5050                 5055             


Asp Val  Asp Val Asn Ile Ala  Gly Pro Asp Ala Ala  Leu Lys Val 
    5060                 5065                 5070             


Asp Val  Lys Ser Pro Lys Thr  Lys Lys Thr Met Phe  Gly Lys Met 
    5075                 5080                 5085             


Tyr Phe  Pro Asp Val Glu Phe  Asp Ile Lys Ser Pro  Lys Phe Lys 
    5090                 5095                 5100             


Ala Glu  Ala Pro Leu Pro Ser  Pro Lys Leu Glu Gly  Glu Leu Gln 
    5105                 5110                 5115             


Ala Pro  Asp Leu Glu Leu Ser  Leu Pro Ala Ile His  Val Glu Gly 
    5120                 5125                 5130             


Leu Asp  Ile Lys Ala Lys Ala  Pro Lys Val Lys Met  Pro Asp Val 
    5135                 5140                 5145             


Asp Ile  Ser Val Pro Lys Ile  Glu Gly Asp Leu Lys  Gly Pro Lys 
    5150                 5155                 5160             


Val Gln  Ala Asn Leu Gly Ala  Pro Asp Ile Asn Ile  Glu Gly Leu 
    5165                 5170                 5175             


Asp Ala  Lys Val Lys Thr Pro  Ser Phe Gly Ile Ser  Ala Pro Gln 
    5180                 5185                 5190             


Val Ser  Ile Pro Asp Val Asn  Val Asn Leu Lys Gly  Pro Lys Ile 
    5195                 5200                 5205             


Lys Gly  Asp Val Pro Ser Val  Gly Leu Glu Gly Pro  Asp Val Asp 
    5210                 5215                 5220             


Leu Gln  Gly Pro Glu Ala Lys  Ile Lys Phe Pro Lys  Phe Ser Met 
    5225                 5230                 5235             


Pro Lys  Ile Gly Ile Pro Gly  Val Lys Met Glu Gly  Gly Gly Ala 
    5240                 5245                 5250             


Glu Val  His Ala Gln Leu Pro  Ser Leu Glu Gly Asp  Leu Arg Gly 
    5255                 5260                 5265             


Pro Asp  Val Lys Leu Glu Gly  Pro Asp Val Ser Leu  Lys Gly Pro 
    5270                 5275                 5280             


Gly Val  Asp Leu Pro Ser Val  Asn Leu Ser Met Pro  Lys Val Ser 
    5285                 5290                 5295             


Gly Pro  Asp Leu Asp Leu Asn  Leu Lys Gly Pro Ser  Leu Lys Gly 
    5300                 5305                 5310             


Asp Leu  Asp Ala Ser Val Pro  Ser Met Lys Val His  Ala Pro Gly 
    5315                 5320                 5325             


Leu Asn  Leu Ser Gly Val Gly  Gly Lys Met Gln Val  Gly Gly Asp 
    5330                 5335                 5340             


Gly Val  Lys Val Pro Gly Ile  Asp Ala Thr Thr Lys  Leu Asn Val 
    5345                 5350                 5355             


Gly Ala  Pro Asp Val Thr Leu  Arg Gly Pro Ser Leu  Gln Gly Asp 
    5360                 5365                 5370             


Leu Ala  Val Ser Gly Asp Ile  Lys Cys Pro Lys Val  Ser Val Gly 
    5375                 5380                 5385             


Ala Pro  Asp Leu Ser Leu Glu  Ala Ser Glu Gly Ser  Ile Lys Leu 
    5390                 5395                 5400             


Pro Lys  Met Lys Leu Pro Gln  Phe Gly Ile Ser Thr  Pro Gly Ser 
    5405                 5410                 5415             


Asp Leu  His Val Asn Ala Lys  Gly Pro Gln Val Ser  Gly Glu Leu 
    5420                 5425                 5430             


Lys Gly  Pro Gly Val Asp Val  Asn Leu Lys Gly Pro  Arg Ile Ser 
    5435                 5440                 5445             


Ala Pro  Asn Val Asp Phe Asn  Leu Glu Gly Pro Lys  Val Lys Gly 
    5450                 5455                 5460             


Ser Leu  Gly Ala Thr Gly Glu  Ile Lys Gly Pro Thr  Val Gly Gly 
    5465                 5470                 5475             


Gly Leu  Pro Gly Ile Gly Val  Gln Gly Leu Glu Gly  Asn Leu Gln 
    5480                 5485                 5490             


Met Pro  Gly Ile Lys Ser Ser  Gly Cys Asp Val Asn  Leu Pro Gly 
    5495                 5500                 5505             


Val Asn  Val Lys Leu Pro Thr  Gly Gln Ile Ser Gly  Pro Glu Ile 
    5510                 5515                 5520             


Lys Gly  Gly Leu Lys Gly Ser  Glu Val Gly Phe His  Gly Ala Ala 
    5525                 5530                 5535             


Pro Asp  Ile Ser Val Lys Gly  Pro Ala Phe Asn Met  Ala Ser Pro 
    5540                 5545                 5550             


Glu Ser  Asp Phe Gly Ile Asn  Leu Lys Gly Pro Lys  Ile Lys Gly 
    5555                 5560                 5565             


Gly Ala  Asp Val Ser Gly Gly  Val Ser Ala Pro Asp  Ile Ser Leu 
    5570                 5575                 5580             


Gly Glu  Gly His Leu Ser Val  Lys Gly Ser Gly Gly  Glu Trp Lys 
    5585                 5590                 5595             


Gly Pro  Gln Val Ser Ser Ala  Leu Asn Leu Asp Thr  Ser Lys Phe 
    5600                 5605                 5610             


Ala Gly  Gly Leu His Phe Ser  Gly Pro Lys Val Glu  Gly Gly Val 
    5615                 5620                 5625             


Lys Gly  Gly Gln Ile Gly Leu  Gln Ala Pro Gly Leu  Ser Val Ser 
    5630                 5635                 5640             


Gly Pro  Gln Gly His Leu Glu  Ser Gly Ser Gly Lys  Val Thr Phe 
    5645                 5650                 5655             


Pro Lys  Met Lys Ile Pro Lys  Phe Thr Phe Ser Gly  Arg Glu Leu 
    5660                 5665                 5670             


Val Gly  Arg Glu Met Gly Val  Asp Val His Phe Pro  Lys Ala Glu 
    5675                 5680                 5685             


Ala Ser  Ile Gln Ala Gly Ala  Gly Asp Gly Glu Trp  Glu Glu Ser 
    5690                 5695                 5700             


Glu Val  Lys Leu Lys Lys Ser  Lys Ile Lys Met Pro  Lys Phe Asn 
    5705                 5710                 5715             


Phe Ser  Lys Pro Lys Gly Lys  Gly Gly Val Thr Gly  Ser Pro Glu 
    5720                 5725                 5730             


Ala Ser  Ile Ser Gly Ser Lys  Gly Asp Leu Lys Ser  Ser Lys Ala 
    5735                 5740                 5745             


Ser Leu  Gly Ser Leu Glu Gly  Glu Ala Glu Ala Glu  Ala Ser Ser 
    5750                 5755                 5760             


Pro Lys  Gly Lys Phe Ser Leu  Phe Lys Ser Lys Lys  Pro Arg His 
    5765                 5770                 5775             


Arg Ser  Asn Ser Phe Ser Asp  Glu Arg Glu Phe Ser  Gly Pro Ser 
    5780                 5785                 5790             


Thr Pro  Thr Gly Thr Leu Glu  Phe Glu Gly Gly Glu  Val Ser Leu 
    5795                 5800                 5805             


Glu Gly  Gly Lys Val Lys Gly  Lys His Gly Lys Leu  Lys Phe Gly 
    5810                 5815                 5820             


Thr Phe  Gly Gly Leu Gly Ser  Lys Ser Lys Gly His  Tyr Glu Val 
    5825                 5830                 5835             


Thr Gly  Ser Asp Asp Glu Thr  Gly Lys Leu Gln Gly  Ser Gly Val 
    5840                 5845                 5850             


Ser Leu  Ala Ser Lys Lys Ser  Arg Leu Ser Ser Ser  Ser Ser Asn 
    5855                 5860                 5865             


Asp Ser  Gly Asn Lys Val Gly  Ile Gln Leu Pro Glu  Val Glu Leu 
    5870                 5875                 5880             


Ser Val  Ser Thr Lys Lys Glu  
    5885                 5890 


<210>  2940
<211>  230
<212>  PRT
<213>  homo sapiens

<400>  2940

Met Glu Ala Ala Glu Thr Glu Ala Glu Ala Ala Ala Leu Glu Val Leu 
1               5                   10                  15      


Ala Glu Val Ala Gly Ile Leu Glu Pro Val Gly Leu Gln Glu Glu Ala 
            20                  25                  30          


Glu Leu Pro Ala Lys Ile Leu Val Glu Phe Val Val Asp Ser Gln Lys 
        35                  40                  45              


Lys Asp Lys Leu Leu Cys Ser Gln Leu Gln Val Ala Asp Phe Leu Gln 
    50                  55                  60                  


Asn Ile Leu Ala Gln Glu Asp Thr Ala Lys Gly Leu Asp Pro Leu Ala 
65                  70                  75                  80  


Ser Glu Asp Thr Ser Arg Gln Lys Ala Ile Ala Ala Lys Glu Gln Trp 
                85                  90                  95      


Lys Glu Leu Lys Ala Thr Tyr Arg Glu His Val Glu Ala Ile Lys Ile 
            100                 105                 110         


Gly Leu Thr Lys Ala Leu Thr Gln Met Glu Glu Ala Gln Arg Lys Arg 
        115                 120                 125             


Thr Gln Leu Arg Glu Ala Phe Glu Gln Leu Gln Ala Lys Lys Gln Met 
    130                 135                 140                 


Ala Met Glu Lys Arg Arg Ala Val Gln Asn Gln Trp Gln Leu Gln Gln 
145                 150                 155                 160 


Glu Lys His Leu Gln His Leu Ala Glu Val Ser Ala Glu Gly Lys Leu 
                165                 170                 175     


Leu Phe Pro Glu Ala Glu Ala Glu Ala Glu Asn Leu Pro Asp Asp Lys 
            180                 185                 190         


Pro Gln Gln Pro Thr Arg Pro Gln Glu Gln Ser Thr Gly Asp Thr Met 
        195                 200                 205             


Gly Arg Asp Pro Gly Val Ser Phe Lys Ala Val Gly Leu Gln Pro Ala 
    210                 215                 220                 


Gly Asp Val Asn Leu Pro 
225                 230 


<210>  2941
<211>  998
<212>  PRT
<213>  homo sapiens

<400>  2941

Met Val Phe Gln Thr Arg Tyr Pro Ser Trp Ile Ile Leu Cys Tyr Ile 
1               5                   10                  15      


Trp Leu Leu Arg Phe Ala His Thr Gly Glu Ala Gln Ala Ala Lys Glu 
            20                  25                  30          


Val Leu Leu Leu Asp Ser Lys Ala Gln Gln Thr Glu Leu Glu Trp Ile 
        35                  40                  45              


Ser Ser Pro Pro Asn Gly Trp Glu Glu Ile Ser Gly Leu Asp Glu Asn 
    50                  55                  60                  


Tyr Thr Pro Ile Arg Thr Tyr Gln Val Cys Gln Val Met Glu Pro Asn 
65                  70                  75                  80  


Gln Asn Asn Trp Leu Arg Thr Asn Trp Ile Ser Lys Gly Asn Ala Gln 
                85                  90                  95      


Arg Ile Phe Val Glu Leu Lys Phe Thr Leu Arg Asp Cys Asn Ser Leu 
            100                 105                 110         


Pro Gly Val Leu Gly Thr Cys Lys Glu Thr Phe Asn Leu Tyr Tyr Tyr 
        115                 120                 125             


Glu Thr Asp Tyr Asp Thr Gly Arg Asn Ile Arg Glu Asn Leu Tyr Val 
    130                 135                 140                 


Lys Ile Asp Thr Ile Ala Ala Asp Glu Ser Phe Thr Gln Gly Asp Leu 
145                 150                 155                 160 


Gly Glu Arg Lys Met Lys Leu Asn Thr Glu Val Arg Glu Ile Gly Pro 
                165                 170                 175     


Leu Ser Lys Lys Gly Phe Tyr Leu Ala Phe Gln Asp Val Gly Ala Cys 
            180                 185                 190         


Ile Ala Leu Val Ser Val Lys Val Tyr Tyr Lys Lys Cys Trp Ser Ile 
        195                 200                 205             


Ile Glu Asn Leu Ala Ile Phe Pro Asp Thr Val Thr Gly Ser Glu Phe 
    210                 215                 220                 


Ser Ser Leu Val Glu Val Arg Gly Thr Cys Val Ser Ser Ala Glu Glu 
225                 230                 235                 240 


Glu Ala Glu Asn Ala Pro Arg Met His Cys Ser Ala Glu Gly Glu Trp 
                245                 250                 255     


Leu Val Pro Ile Gly Lys Cys Ile Cys Lys Ala Gly Tyr Gln Gln Lys 
            260                 265                 270         


Gly Asp Thr Cys Glu Pro Cys Gly Arg Gly Phe Tyr Lys Ser Ser Ser 
        275                 280                 285             


Gln Asp Leu Gln Cys Ser Arg Cys Pro Thr His Ser Phe Ser Asp Lys 
    290                 295                 300                 


Glu Gly Ser Ser Arg Cys Glu Cys Glu Asp Gly Tyr Tyr Arg Ala Pro 
305                 310                 315                 320 


Ser Asp Pro Pro Tyr Val Ala Cys Thr Arg Pro Pro Ser Ala Pro Gln 
                325                 330                 335     


Asn Leu Ile Phe Asn Ile Asn Gln Thr Thr Val Ser Leu Glu Trp Ser 
            340                 345                 350         


Pro Pro Ala Asp Asn Gly Gly Arg Asn Asp Val Thr Tyr Arg Ile Leu 
        355                 360                 365             


Cys Lys Arg Cys Ser Trp Glu Gln Gly Glu Cys Val Pro Cys Gly Ser 
    370                 375                 380                 


Asn Ile Gly Tyr Met Pro Gln Gln Thr Gly Leu Glu Asp Asn Tyr Val 
385                 390                 395                 400 


Thr Val Met Asp Leu Leu Ala His Ala Asn Tyr Thr Phe Glu Val Glu 
                405                 410                 415     


Ala Val Asn Gly Val Ser Asp Leu Ser Arg Ser Gln Arg Leu Phe Ala 
            420                 425                 430         


Ala Val Ser Ile Thr Thr Gly Gln Ala Ala Pro Ser Gln Val Ser Gly 
        435                 440                 445             


Val Met Lys Glu Arg Val Leu Gln Arg Ser Val Glu Leu Ser Trp Gln 
    450                 455                 460                 


Glu Pro Glu His Pro Asn Gly Val Ile Thr Glu Tyr Glu Ile Lys Tyr 
465                 470                 475                 480 


Tyr Glu Lys Asp Gln Arg Glu Arg Thr Tyr Ser Thr Val Lys Thr Lys 
                485                 490                 495     


Ser Thr Ser Ala Ser Ile Asn Asn Leu Lys Pro Gly Thr Val Tyr Val 
            500                 505                 510         


Phe Gln Ile Arg Ala Phe Thr Ala Ala Gly Tyr Gly Asn Tyr Ser Pro 
        515                 520                 525             


Arg Leu Asp Val Ala Thr Leu Glu Glu Ala Thr Gly Lys Met Phe Glu 
    530                 535                 540                 


Ala Thr Ala Val Ser Ser Glu Gln Asn Pro Val Ile Ile Ile Ala Val 
545                 550                 555                 560 


Val Ala Val Ala Gly Thr Ile Ile Leu Val Phe Met Val Phe Gly Phe 
                565                 570                 575     


Ile Ile Gly Arg Arg His Cys Gly Tyr Ser Lys Ala Asp Gln Glu Gly 
            580                 585                 590         


Asp Glu Glu Leu Tyr Phe His Phe Lys Phe Pro Gly Thr Lys Thr Tyr 
        595                 600                 605             


Ile Asp Pro Glu Thr Tyr Glu Asp Pro Asn Arg Ala Val His Gln Phe 
    610                 615                 620                 


Ala Lys Glu Leu Asp Ala Ser Cys Ile Lys Ile Glu Arg Val Ile Gly 
625                 630                 635                 640 


Ala Gly Glu Phe Gly Glu Val Cys Ser Gly Arg Leu Lys Leu Pro Gly 
                645                 650                 655     


Lys Arg Asp Val Ala Val Ala Ile Lys Thr Leu Lys Val Gly Tyr Thr 
            660                 665                 670         


Glu Lys Gln Arg Arg Asp Phe Leu Cys Glu Ala Ser Ile Met Gly Gln 
        675                 680                 685             


Phe Asp His Pro Asn Val Val His Leu Glu Gly Val Val Thr Arg Gly 
    690                 695                 700                 


Lys Pro Val Met Ile Val Ile Glu Phe Met Glu Asn Gly Ala Leu Asp 
705                 710                 715                 720 


Ala Phe Leu Arg Lys His Asp Gly Gln Phe Thr Val Ile Gln Leu Val 
                725                 730                 735     


Gly Met Leu Arg Gly Ile Ala Ala Gly Met Arg Tyr Leu Ala Asp Met 
            740                 745                 750         


Gly Tyr Val His Arg Asp Leu Ala Ala Arg Asn Ile Leu Val Asn Ser 
        755                 760                 765             


Asn Leu Val Cys Lys Val Ser Asp Phe Gly Leu Ser Arg Val Ile Glu 
    770                 775                 780                 


Asp Asp Pro Glu Ala Val Tyr Thr Thr Thr Gly Gly Lys Ile Pro Val 
785                 790                 795                 800 


Arg Trp Thr Ala Pro Glu Ala Ile Gln Tyr Arg Lys Phe Thr Ser Ala 
                805                 810                 815     


Ser Asp Val Trp Ser Tyr Gly Ile Val Met Trp Glu Val Met Ser Tyr 
            820                 825                 830         


Gly Glu Arg Pro Tyr Trp Asp Met Ser Asn Gln Asp Val Ile Lys Ala 
        835                 840                 845             


Ile Glu Glu Gly Tyr Arg Leu Pro Ala Pro Met Asp Cys Pro Ala Gly 
    850                 855                 860                 


Leu His Gln Leu Met Leu Asp Cys Trp Gln Lys Glu Arg Ala Glu Arg 
865                 870                 875                 880 


Pro Lys Phe Glu Gln Ile Val Gly Ile Leu Asp Lys Met Ile Arg Asn 
                885                 890                 895     


Pro Asn Ser Leu Lys Thr Pro Leu Gly Thr Cys Ser Arg Pro Ile Ser 
            900                 905                 910         


Pro Leu Leu Asp Gln Asn Thr Pro Asp Phe Thr Thr Phe Cys Ser Val 
        915                 920                 925             


Gly Glu Trp Leu Gln Ala Ile Lys Met Glu Arg Tyr Lys Asp Asn Phe 
    930                 935                 940                 


Thr Ala Ala Gly Tyr Asn Ser Leu Glu Ser Val Ala Arg Met Thr Ile 
945                 950                 955                 960 


Glu Asp Val Met Ser Leu Gly Ile Thr Leu Val Gly His Gln Lys Lys 
                965                 970                 975     


Ile Met Ser Ser Ile Gln Thr Met Arg Ala Gln Met Leu His Leu His 
            980                 985                 990         


Gly Thr Gly Ile Gln Val 
        995             


<210>  2942
<211>  487
<212>  PRT
<213>  homo sapiens

<400>  2942

Met Ala Pro Val Val Thr Gly Lys Phe Gly Glu Arg Pro Pro Pro Lys 
1               5                   10                  15      


Arg Leu Thr Arg Glu Ala Met Arg Asn Tyr Leu Lys Glu Arg Gly Asp 
            20                  25                  30          


Gln Thr Val Leu Ile Leu His Ala Lys Val Ala Gln Lys Ser Tyr Gly 
        35                  40                  45              


Asn Glu Lys Arg Phe Phe Cys Pro Pro Pro Cys Val Tyr Leu Met Gly 
    50                  55                  60                  


Ser Gly Trp Lys Lys Lys Lys Glu Gln Met Glu Arg Asp Gly Cys Ser 
65                  70                  75                  80  


Glu Gln Glu Ser Gln Pro Cys Ala Phe Ile Gly Ile Gly Asn Ser Asp 
                85                  90                  95      


Gln Glu Met Gln Gln Leu Asn Leu Glu Gly Lys Asn Tyr Cys Thr Ala 
            100                 105                 110         


Lys Thr Leu Tyr Ile Ser Asp Ser Asp Lys Arg Lys His Phe Met Leu 
        115                 120                 125             


Ser Val Lys Met Phe Tyr Gly Asn Ser Asp Asp Ile Gly Val Phe Leu 
    130                 135                 140                 


Ser Lys Arg Ile Lys Val Ile Ser Lys Pro Ser Lys Lys Lys Gln Ser 
145                 150                 155                 160 


Leu Lys Asn Ala Asp Leu Cys Ile Ala Ser Gly Thr Lys Val Ala Leu 
                165                 170                 175     


Phe Asn Arg Leu Arg Ser Gln Thr Val Ser Thr Arg Tyr Leu His Val 
            180                 185                 190         


Glu Gly Gly Asn Phe His Ala Ser Ser Gln Gln Trp Gly Ala Phe Phe 
        195                 200                 205             


Ile His Leu Leu Asp Asp Asp Glu Ser Glu Gly Glu Glu Phe Thr Val 
    210                 215                 220                 


Arg Asp Gly Tyr Ile His Tyr Gly Gln Thr Val Lys Leu Val Cys Ser 
225                 230                 235                 240 


Val Thr Gly Met Ala Leu Pro Arg Leu Ile Ile Arg Lys Val Asp Lys 
                245                 250                 255     


Gln Thr Ala Leu Leu Asp Ala Asp Asp Pro Val Ser Gln Leu His Lys 
            260                 265                 270         


Cys Ala Phe Tyr Leu Lys Asp Thr Glu Arg Met Tyr Leu Cys Leu Ser 
        275                 280                 285             


Gln Glu Arg Ile Ile Gln Phe Gln Ala Thr Pro Cys Pro Lys Glu Pro 
    290                 295                 300                 


Asn Lys Glu Met Ile Asn Asp Gly Ala Ser Trp Thr Ile Ile Ser Thr 
305                 310                 315                 320 


Asp Lys Ala Glu Tyr Thr Phe Tyr Glu Gly Met Gly Pro Val Leu Ala 
                325                 330                 335     


Pro Val Thr Pro Val Pro Val Val Glu Ser Leu Gln Leu Asn Gly Gly 
            340                 345                 350         


Gly Asp Val Ala Met Leu Glu Leu Thr Gly Gln Asn Phe Thr Pro Asn 
        355                 360                 365             


Leu Arg Val Trp Phe Gly Asp Val Glu Ala Glu Thr Met Tyr Arg Cys 
    370                 375                 380                 


Gly Glu Ser Met Leu Cys Val Val Pro Asp Ile Ser Ala Phe Arg Glu 
385                 390                 395                 400 


Gly Trp Arg Trp Val Arg Gln Pro Val Gln Val Pro Val Thr Leu Val 
                405                 410                 415     


Arg Asn Asp Gly Ile Ile Tyr Ser Thr Ser Leu Thr Phe Thr Tyr Thr 
            420                 425                 430         


Pro Glu Pro Gly Pro Arg Pro His Cys Ser Ala Ala Gly Ala Ile Leu 
        435                 440                 445             


Arg Ala Asn Ser Ser Gln Val Pro Pro Asn Glu Ser Asn Thr Asn Ser 
    450                 455                 460                 


Glu Gly Ser Tyr Thr Asn Ala Ser Thr Asn Ser Thr Ser Val Thr Ser 
465                 470                 475                 480 


Ser Thr Ala Thr Val Val Ser 
                485         


<210>  2943
<211>  371
<212>  PRT
<213>  homo sapiens

<400>  2943

Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Pro Gly Gln Thr Pro Glu Ala Ala Lys Glu Ala Glu Leu Ala Ala Arg 
            20                  25                  30          


Ile Leu Leu Asp Gln Gly Gln Thr His Ser Val Glu Thr Pro Tyr Gly 
        35                  40                  45              


Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg Pro Ala 
    50                  55                  60                  


Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys Phe Gln 
65                  70                  75                  80  


Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn Phe Val 
                85                  90                  95      


Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro Val Phe 
            100                 105                 110         


Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp Met Ile 
        115                 120                 125             


Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly Val Gly 
    130                 135                 140                 


Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn His Pro 
145                 150                 155                 160 


Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn Ala Lys 
                165                 170                 175     


Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr Ser Ser 
            180                 185                 190         


Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu Leu Ser 
        195                 200                 205             


Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr His Ala 
    210                 215                 220                 


Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn Asn Arg 
225                 230                 235                 240 


Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg Cys Pro 
                245                 250                 255     


Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala Val Val 
            260                 265                 270         


Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu Lys Met 
        275                 280                 285             


Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Gln Pro Gly Lys Leu Thr 
    290                 295                 300                 


Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr Met Ala Ser Ser 
305                 310                 315                 320 


Cys Met Thr Arg Leu Ser Arg Ser Arg Thr Ala Ser Leu Thr Ser Ala 
                325                 330                 335     


Ala Ser Val Asp Gly Asn Arg Ser Arg Ser Arg Thr Leu Ser Gln Ser 
            340                 345                 350         


Ser Glu Ser Gly Thr Leu Ser Ser Gly Pro Pro Gly His Thr Met Glu 
        355                 360                 365             


Val Ser Cys 
    370     


<210>  2944
<211>  101
<212>  PRT
<213>  homo sapiens

<400>  2944

Met Ala Cys Pro Leu Glu Lys Ala Leu Asp Val Met Val Ser Thr Phe 
1               5                   10                  15      


His Lys Tyr Ser Gly Lys Glu Gly Asp Lys Phe Lys Leu Asn Lys Ser 
            20                  25                  30          


Glu Leu Lys Glu Leu Leu Thr Arg Glu Leu Pro Ser Phe Leu Gly Lys 
        35                  40                  45              


Arg Thr Asp Glu Ala Ala Phe Gln Lys Leu Met Ser Asn Leu Asp Ser 
    50                  55                  60                  


Asn Arg Asp Asn Glu Val Asp Phe Gln Glu Tyr Cys Val Phe Leu Ser 
65                  70                  75                  80  


Cys Ile Ala Met Met Cys Asn Glu Phe Phe Glu Gly Phe Pro Asp Lys 
                85                  90                  95      


Gln Pro Arg Lys Lys 
            100     


<210>  2945
<211>  156
<212>  PRT
<213>  homo sapiens

<400>  2945

Met Phe Leu Thr Glu Asp Leu Ile Thr Phe Asn Leu Arg Asn Phe Leu 
1               5                   10                  15      


Leu Phe Gln Leu Trp Glu Ser Ser Phe Ser Pro Gly Ala Gly Gly Phe 
            20                  25                  30          


Cys Thr Thr Leu Pro Pro Ser Phe Leu Arg Val Asp Asp Arg Ala Thr 
        35                  40                  45              


Ser Ser Thr Thr Asp Ser Ser Arg Ala Pro Ser Ser Pro Arg Pro Pro 
    50                  55                  60                  


Gly Ser Thr Ser His Cys Gly Ile Ser Thr Arg Cys Thr Glu Arg Cys 
65                  70                  75                  80  


Leu Cys Val Leu Pro Leu Arg Thr Ser Gln Val Pro Asp Val Met Ala 
                85                  90                  95      


Pro Gln His Asp Gln Glu Lys Phe His Asp Leu Ala Tyr Ser Cys Leu 
            100                 105                 110         


Gly Lys Ser Phe Ser Met Ser Asn Gln Asp Leu Tyr Gly Tyr Ser Thr 
        115                 120                 125             


Ser Ser Leu Ala Leu Gly Leu Ala Trp Leu Ser Trp Glu Thr Lys Lys 
    130                 135                 140                 


Lys Asn Val Leu His Leu Val Gly Leu Asp Ser Leu 
145                 150                 155     


<210>  2946
<211>  270
<212>  PRT
<213>  homo sapiens

<400>  2946

Met Ser Pro Gly Ser Gly Val Lys Ser Glu Tyr Met Lys Arg Tyr Gln 
1               5                   10                  15      


Glu Pro Arg Trp Glu Glu Tyr Gly Pro Cys Tyr Arg Glu Leu Leu His 
            20                  25                  30          


Tyr Arg Leu Gly Arg Arg Leu Leu Glu Gln Ala His Ala Pro Trp Leu 
        35                  40                  45              


Trp Asp Asp Trp Gly Pro Ala Gly Ser Ser Glu Asp Ser Ala Ser Ser 
    50                  55                  60                  


Glu Ser Ser Gly Ala Gly Gly Pro Ala Pro Arg Cys Ala Pro Pro Ser 
65                  70                  75                  80  


Pro Pro Pro Pro Val Glu Pro Ala Thr Gln Glu Glu Ala Glu Arg Arg 
                85                  90                  95      


Ala Arg Gly Ala Pro Glu Glu Gln Asp Ala Glu Ala Gly Asp Ala Glu 
            100                 105                 110         


Ala Glu Asp Ala Glu Asp Ala Ala Leu Pro Ala Leu Pro Val Lys Asp 
        115                 120                 125             


Val Glu Asp Lys Pro Glu Gln Gln Thr Arg Thr Arg Glu Thr Asp Lys 
    130                 135                 140                 


Ser Pro Thr Ser Thr Glu Pro Arg Gln Gln Pro Ser Ala Leu Phe Ala 
145                 150                 155                 160 


Arg Gly Asn Arg Lys Ala Val Lys Ser Pro Gln Arg Ser Ser Ser Lys 
                165                 170                 175     


Ile Lys Glu Asn Lys His Pro Phe Ala Leu Tyr Gly Trp Gly Glu Lys 
            180                 185                 190         


Gln Thr Asp Thr Gly Ser Gln Lys Thr His Asn Val Cys Ala Ser Ala 
        195                 200                 205             


Pro Val His Glu Ile His Glu Ser Ala Leu Arg Ala Lys Asn Arg Arg 
    210                 215                 220                 


Gln Val Glu Lys Arg Lys Leu Val Ala Gln Arg Gln Arg Ala His Ser 
225                 230                 235                 240 


Val Asp Val Glu Lys Asn Arg Lys Met Lys Ala Ser Ser Ser Glu Asn 
                245                 250                 255     


Pro Trp Met Thr Glu Tyr Met Arg Cys Tyr Ser Ala Arg Ala 
            260                 265                 270 


<210>  2947
<211>  102
<212>  PRT
<213>  homo sapiens

<400>  2947

Met Gln Arg Val Ser Gly Leu Leu Ser Trp Thr Leu Ser Arg Val Leu 
1               5                   10                  15      


Trp Leu Ser Gly Leu Ser Glu Pro Gly Ala Ala Arg Gln Pro Arg Ile 
            20                  25                  30          


Met Glu Glu Lys Ala Leu Glu Val Tyr Asp Leu Ile Arg Thr Ile Arg 
        35                  40                  45              


Asp Pro Glu Lys Pro Asn Thr Leu Glu Glu Leu Glu Val Val Ser Glu 
    50                  55                  60                  


Ser Cys Val Glu Val Gln Glu Ile Asn Glu Glu Glu Tyr Leu Val Ile 
65                  70                  75                  80  


Ile Arg Phe Thr Pro Thr Val Pro His Cys Ser Leu Ala Thr Leu Ile 
                85                  90                  95      


Val Gly Asn Leu His Phe 
            100         


<210>  2948
<211>  454
<212>  PRT
<213>  homo sapiens

<400>  2948

Met Thr Lys Arg Glu Ala Glu Glu Leu Ile Glu Ile Glu Ile Asp Gly 
1               5                   10                  15      


Thr Glu Lys Ala Glu Cys Thr Glu Glu Ser Ile Val Glu Gln Thr Tyr 
            20                  25                  30          


Ala Pro Ala Glu Cys Val Ser Gln Ala Ile Asp Ile Asn Glu Pro Ile 
        35                  40                  45              


Gly Asn Leu Lys Lys Leu Leu Glu Pro Arg Leu Gln Cys Ser Leu Asp 
    50                  55                  60                  


Ala His Glu Ile Cys Leu Gln Asp Ile Gln Leu Asp Pro Glu Arg Ser 
65                  70                  75                  80  


Leu Phe Asp Gln Gly Val Lys Thr Asp Gly Thr Val Gln Leu Ser Val 
                85                  90                  95      


Gln Val Ile Ser Tyr Gln Gly Ile Glu Pro Lys Leu Asn Ile Leu Glu 
            100                 105                 110         


Ile Val Lys Pro Ala Asp Thr Val Glu Val Val Ile Asp Pro Asp Ala 
        115                 120                 125             


His His Ala Glu Ser Glu Ala His Leu Val Glu Glu Ala Gln Val Ile 
    130                 135                 140                 


Thr Leu Asp Gly Thr Lys His Ile Thr Thr Ile Ser Asp Glu Thr Ser 
145                 150                 155                 160 


Glu Gln Val Thr Arg Trp Ala Ala Ala Leu Glu Gly Tyr Arg Lys Glu 
                165                 170                 175     


Gln Glu Arg Leu Gly Ile Pro Tyr Asp Pro Ile Gln Trp Ser Thr Asp 
            180                 185                 190         


Gln Val Leu His Trp Val Val Trp Val Met Lys Glu Phe Ser Met Thr 
        195                 200                 205             


Asp Ile Asp Leu Thr Thr Leu Asn Ile Ser Gly Arg Glu Leu Cys Ser 
    210                 215                 220                 


Leu Asn Gln Glu Asp Phe Phe Gln Arg Val Pro Arg Gly Glu Ile Leu 
225                 230                 235                 240 


Trp Ser His Leu Glu Leu Leu Arg Lys Tyr Val Leu Ala Ser Gln Glu 
                245                 250                 255     


Gln Gln Met Asn Glu Ile Val Thr Ile Asp Gln Pro Val Gln Ile Ile 
            260                 265                 270         


Pro Ala Ser Val Gln Ser Ala Thr Pro Thr Thr Ile Lys Val Ile Asn 
        275                 280                 285             


Ser Ser Ala Lys Ala Ala Lys Val Gln Arg Ala Pro Arg Ile Ser Gly 
    290                 295                 300                 


Glu Asp Arg Ser Ser Pro Gly Asn Arg Thr Gly Asn Asn Gly Gln Ile 
305                 310                 315                 320 


Gln Leu Trp Gln Phe Leu Leu Glu Leu Leu Thr Asp Lys Asp Ala Arg 
                325                 330                 335     


Asp Cys Ile Ser Trp Val Gly Asp Glu Gly Glu Phe Lys Leu Asn Gln 
            340                 345                 350         


Pro Glu Leu Val Ala Gln Lys Trp Gly Gln Arg Lys Asn Lys Pro Thr 
        355                 360                 365             


Met Asn Tyr Glu Lys Leu Ser Arg Ala Leu Arg Tyr Tyr Tyr Asp Gly 
    370                 375                 380                 


Asp Met Ile Cys Lys Val Gln Gly Lys Arg Phe Val Tyr Lys Phe Val 
385                 390                 395                 400 


Cys Asp Leu Lys Thr Leu Ile Gly Tyr Ser Ala Ala Glu Leu Asn Arg 
                405                 410                 415     


Leu Val Thr Glu Cys Glu Gln Lys Lys Leu Ala Lys Met Gln Leu His 
            420                 425                 430         


Gly Ile Ala Gln Pro Val Thr Ala Val Ala Leu Ala Thr Ala Ser Leu 
        435                 440                 445             


Gln Thr Glu Lys Asp Asn 
    450                 


<210>  2949
<211>  423
<212>  PRT
<213>  homo sapiens

<400>  2949

Met Ser Ser Gln Val Val Gly Ile Glu Pro Leu Tyr Ile Lys Ala Glu 
1               5                   10                  15      


Pro Ala Ser Pro Asp Ser Pro Lys Gly Ser Ser Glu Thr Glu Thr Glu 
            20                  25                  30          


Pro Pro Val Ala Leu Ala Pro Gly Pro Ala Pro Thr Arg Cys Leu Pro 
        35                  40                  45              


Gly His Lys Glu Glu Glu Asp Gly Glu Gly Ala Gly Pro Gly Glu Gln 
    50                  55                  60                  


Gly Gly Gly Lys Leu Val Leu Ser Ser Leu Pro Lys Arg Leu Cys Leu 
65                  70                  75                  80  


Val Cys Gly Asp Val Ala Ser Gly Tyr His Tyr Gly Val Ala Ser Cys 
                85                  90                  95      


Glu Ala Cys Lys Ala Phe Phe Lys Arg Thr Ile Gln Gly Ser Ile Glu 
            100                 105                 110         


Tyr Ser Cys Pro Ala Ser Asn Glu Cys Glu Ile Thr Lys Arg Arg Arg 
        115                 120                 125             


Lys Ala Cys Gln Ala Cys Arg Phe Thr Lys Cys Leu Arg Val Gly Met 
    130                 135                 140                 


Leu Lys Glu Gly Val Arg Leu Asp Arg Val Arg Gly Gly Arg Gln Lys 
145                 150                 155                 160 


Tyr Lys Arg Arg Pro Glu Val Asp Pro Leu Pro Phe Pro Gly Pro Phe 
                165                 170                 175     


Pro Ala Gly Pro Leu Ala Val Ala Gly Gly Pro Arg Lys Thr Ala Ala 
            180                 185                 190         


Pro Val Asn Ala Leu Val Ser His Leu Leu Val Val Glu Pro Glu Lys 
        195                 200                 205             


Leu Tyr Ala Met Pro Asp Pro Ala Gly Pro Asp Gly His Leu Pro Ala 
    210                 215                 220                 


Val Ala Thr Leu Cys Asp Leu Phe Asp Arg Glu Ile Val Val Thr Ile 
225                 230                 235                 240 


Ser Trp Ala Lys Ser Ile Pro Gly Phe Ser Ser Leu Ser Leu Ser Asp 
                245                 250                 255     


Gln Met Ser Val Leu Gln Ser Val Trp Met Glu Val Leu Val Leu Gly 
            260                 265                 270         


Val Ala Gln Arg Ser Leu Pro Leu Gln Asp Glu Leu Ala Phe Ala Glu 
        275                 280                 285             


Asp Leu Val Leu Asp Glu Glu Gly Ala Arg Ala Ala Gly Leu Gly Glu 
    290                 295                 300                 


Leu Gly Ala Ala Leu Leu Gln Leu Val Arg Arg Leu Gln Ala Leu Arg 
305                 310                 315                 320 


Leu Glu Arg Glu Glu Tyr Val Leu Leu Lys Ala Leu Ala Leu Ala Asn 
                325                 330                 335     


Ser Asp Ser Val His Ile Glu Asp Ala Glu Ala Val Glu Gln Leu Arg 
            340                 345                 350         


Glu Ala Leu His Glu Ala Leu Leu Glu Tyr Glu Ala Gly Arg Ala Gly 
        355                 360                 365             


Pro Gly Gly Gly Ala Glu Arg Arg Arg Ala Gly Arg Leu Leu Leu Thr 
    370                 375                 380                 


Leu Pro Leu Leu Arg Gln Thr Ala Gly Lys Val Leu Ala His Phe Tyr 
385                 390                 395                 400 


Gly Val Lys Leu Glu Gly Lys Val Pro Met His Lys Leu Phe Leu Glu 
                405                 410                 415     


Met Leu Glu Ala Met Met Asp 
            420             


<210>  2950
<211>  834
<212>  PRT
<213>  homo sapiens

<400>  2950

Met Glu Arg Pro Tyr Thr Phe Lys Asp Phe Leu Leu Arg Pro Arg Ser 
1               5                   10                  15      


His Lys Ser Arg Val Lys Gly Phe Leu Arg Leu Lys Met Ala Tyr Met 
            20                  25                  30          


Pro Lys Asn Gly Gly Gln Asp Glu Glu Asn Ser Asp Gln Arg Asp Asp 
        35                  40                  45              


Met Glu His Gly Trp Glu Val Val Asp Ser Asn Asp Ser Ala Ser Gln 
    50                  55                  60                  


His Gln Glu Glu Leu Pro Pro Pro Pro Leu Pro Pro Gly Trp Glu Glu 
65                  70                  75                  80  


Lys Val Asp Asn Leu Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg 
                85                  90                  95      


Thr Thr Gln Trp His Arg Pro Ser Leu Met Asp Val Ser Ser Glu Ser 
            100                 105                 110         


Asp Asn Asn Ile Arg Gln Ile Asn Gln Glu Ala Ala His Arg Arg Phe 
        115                 120                 125             


Arg Ser Arg Arg His Ile Ser Glu Asp Leu Glu Pro Glu Pro Ser Glu 
    130                 135                 140                 


Gly Gly Asp Val Pro Glu Pro Trp Glu Thr Ile Ser Glu Glu Val Asn 
145                 150                 155                 160 


Ile Ala Gly Asp Ser Leu Gly Leu Ala Leu Pro Pro Pro Pro Ala Ser 
                165                 170                 175     


Pro Gly Ser Arg Thr Ser Pro Gln Glu Leu Ser Glu Glu Leu Ser Arg 
            180                 185                 190         


Arg Leu Gln Ile Thr Pro Asp Ser Asn Gly Glu Gln Phe Ser Ser Leu 
        195                 200                 205             


Ile Gln Arg Glu Pro Ser Ser Arg Leu Arg Ser Cys Ser Val Thr Asp 
    210                 215                 220                 


Ala Val Ala Glu Gln Gly His Leu Pro Pro Pro Ser Val Ala Tyr Val 
225                 230                 235                 240 


His Thr Thr Pro Gly Leu Pro Ser Gly Trp Glu Glu Arg Lys Asp Ala 
                245                 250                 255     


Lys Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg Thr Thr Thr Trp 
            260                 265                 270         


Thr Arg Pro Ile Met Gln Leu Ala Glu Asp Gly Ala Ser Gly Ser Ala 
        275                 280                 285             


Thr Asn Ser Asn Asn His Leu Ile Glu Pro Gln Ile Arg Arg Pro Arg 
    290                 295                 300                 


Ser Leu Ser Ser Pro Thr Val Thr Leu Ser Ala Pro Leu Glu Gly Ala 
305                 310                 315                 320 


Lys Asp Ser Pro Val Arg Arg Ala Val Lys Asp Thr Leu Ser Asn Pro 
                325                 330                 335     


Gln Ser Pro Gln Pro Ser Pro Tyr Asn Ser Pro Lys Pro Gln His Lys 
            340                 345                 350         


Val Thr Gln Ser Phe Leu Pro Pro Gly Trp Glu Met Arg Ile Ala Pro 
        355                 360                 365             


Asn Gly Arg Pro Phe Phe Ile Asp His Asn Thr Lys Thr Thr Thr Trp 
    370                 375                 380                 


Glu Asp Pro Arg Leu Lys Phe Pro Val His Met Arg Ser Lys Thr Ser 
385                 390                 395                 400 


Leu Asn Pro Asn Asp Leu Gly Pro Leu Pro Pro Gly Trp Glu Glu Arg 
                405                 410                 415     


Ile His Leu Asp Gly Arg Thr Phe Tyr Ile Asp His Asn Ser Lys Ile 
            420                 425                 430         


Thr Gln Trp Glu Asp Pro Arg Leu Gln Asn Pro Ala Ile Thr Gly Pro 
        435                 440                 445             


Ala Val Pro Tyr Ser Arg Glu Phe Lys Gln Lys Tyr Asp Tyr Phe Arg 
    450                 455                 460                 


Lys Lys Leu Lys Lys Pro Ala Asp Ile Pro Asn Arg Phe Glu Met Lys 
465                 470                 475                 480 


Leu His Arg Asn Asn Ile Phe Glu Glu Ser Tyr Arg Arg Ile Met Ser 
                485                 490                 495     


Val Lys Arg Pro Asp Val Leu Lys Ala Arg Leu Trp Ile Glu Phe Glu 
            500                 505                 510         


Ser Glu Lys Gly Leu Asp Tyr Gly Gly Val Ala Arg Glu Trp Phe Phe 
        515                 520                 525             


Leu Leu Ser Lys Glu Met Phe Asn Pro Tyr Tyr Gly Leu Phe Glu Tyr 
    530                 535                 540                 


Ser Ala Thr Asp Asn Tyr Thr Leu Gln Ile Asn Pro Asn Ser Gly Leu 
545                 550                 555                 560 


Cys Asn Glu Asp His Leu Ser Tyr Phe Thr Phe Ile Gly Arg Val Ala 
                565                 570                 575     


Gly Leu Ala Val Phe His Gly Lys Leu Leu Asp Gly Phe Phe Ile Arg 
            580                 585                 590         


Pro Phe Tyr Lys Met Met Leu Gly Lys Gln Ile Thr Leu Asn Asp Met 
        595                 600                 605             


Glu Ser Val Asp Ser Glu Tyr Tyr Asn Ser Leu Lys Trp Ile Leu Glu 
    610                 615                 620                 


Asn Asp Pro Thr Glu Leu Asp Leu Met Phe Cys Ile Asp Glu Glu Asn 
625                 630                 635                 640 


Phe Gly Gln Thr Tyr Gln Val Asp Leu Lys Pro Asn Gly Ser Glu Ile 
                645                 650                 655     


Met Val Thr Asn Glu Asn Lys Arg Glu Tyr Ile Asp Leu Val Ile Gln 
            660                 665                 670         


Trp Arg Phe Val Asn Arg Val Gln Lys Gln Met Asn Ala Phe Leu Glu 
        675                 680                 685             


Gly Phe Thr Glu Leu Leu Pro Ile Asp Leu Ile Lys Ile Phe Asp Glu 
    690                 695                 700                 


Asn Glu Leu Glu Leu Leu Met Cys Gly Leu Gly Asp Val Asp Val Asn 
705                 710                 715                 720 


Asp Trp Arg Gln His Ser Ile Tyr Lys Asn Gly Tyr Cys Pro Asn His 
                725                 730                 735     


Pro Val Ile Gln Trp Phe Trp Lys Ala Val Leu Leu Met Asp Ala Glu 
            740                 745                 750         


Lys Arg Ile Arg Leu Leu Gln Phe Val Thr Gly Thr Ser Arg Val Pro 
        755                 760                 765             


Met Asn Gly Phe Ala Glu Leu Tyr Gly Ser Asn Gly Pro Gln Leu Phe 
    770                 775                 780                 


Thr Ile Glu Gln Trp Gly Ser Pro Glu Lys Leu Pro Arg Ala His Thr 
785                 790                 795                 800 


Cys Phe Asn Arg Leu Asp Leu Pro Pro Tyr Glu Thr Phe Glu Asp Leu 
                805                 810                 815     


Arg Glu Lys Leu Leu Met Ala Val Glu Asn Ala Gln Gly Phe Glu Gly 
            820                 825                 830         


Val Asp 
        


<210>  2951
<211>  854
<212>  PRT
<213>  homo sapiens

<400>  2951

Met Glu Arg Pro Tyr Thr Phe Lys Asp Phe Leu Leu Arg Pro Arg Ser 
1               5                   10                  15      


His Lys Ser Arg Val Lys Gly Phe Leu Arg Leu Lys Met Ala Tyr Met 
            20                  25                  30          


Pro Lys Asn Gly Gly Gln Asp Glu Glu Asn Ser Asp Gln Arg Asp Asp 
        35                  40                  45              


Met Glu His Gly Trp Glu Val Val Asp Ser Asn Asp Ser Ala Ser Gln 
    50                  55                  60                  


His Gln Glu Glu Leu Pro Pro Pro Pro Leu Pro Pro Gly Trp Glu Glu 
65                  70                  75                  80  


Lys Val Asp Asn Leu Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg 
                85                  90                  95      


Thr Thr Gln Trp His Arg Pro Ser Leu Met Asp Val Ser Ser Glu Ser 
            100                 105                 110         


Asp Asn Asn Ile Arg Gln Ile Asn Gln Glu Ala Ala His Arg Arg Phe 
        115                 120                 125             


Arg Ser Arg Arg His Ile Ser Glu Asp Leu Glu Pro Glu Pro Ser Glu 
    130                 135                 140                 


Gly Gly Asp Val Pro Glu Pro Trp Glu Thr Ile Ser Glu Glu Val Asn 
145                 150                 155                 160 


Ile Ala Gly Asp Ser Leu Gly Leu Ala Leu Pro Pro Pro Pro Ala Ser 
                165                 170                 175     


Pro Gly Ser Arg Thr Ser Pro Gln Glu Leu Ser Glu Glu Leu Ser Arg 
            180                 185                 190         


Arg Leu Gln Ile Thr Pro Asp Ser Asn Gly Glu Gln Phe Ser Ser Leu 
        195                 200                 205             


Ile Gln Arg Glu Pro Ser Ser Arg Leu Arg Ser Cys Ser Val Thr Asp 
    210                 215                 220                 


Ala Val Ala Glu Gln Gly His Leu Pro Pro Pro Ser Ala Pro Ala Gly 
225                 230                 235                 240 


Arg Ala Arg Ser Ser Thr Val Thr Gly Gly Glu Glu Pro Thr Pro Ser 
                245                 250                 255     


Val Ala Tyr Val His Thr Thr Pro Gly Leu Pro Ser Gly Trp Glu Glu 
            260                 265                 270         


Arg Lys Asp Ala Lys Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg 
        275                 280                 285             


Thr Thr Thr Trp Thr Arg Pro Ile Met Gln Leu Ala Glu Asp Gly Ala 
    290                 295                 300                 


Ser Gly Ser Ala Thr Asn Ser Asn Asn His Leu Ile Glu Pro Gln Ile 
305                 310                 315                 320 


Arg Arg Pro Arg Ser Leu Ser Ser Pro Thr Val Thr Leu Ser Ala Pro 
                325                 330                 335     


Leu Glu Gly Ala Lys Asp Ser Pro Val Arg Arg Ala Val Lys Asp Thr 
            340                 345                 350         


Leu Ser Asn Pro Gln Ser Pro Gln Pro Ser Pro Tyr Asn Ser Pro Lys 
        355                 360                 365             


Pro Gln His Lys Val Thr Gln Ser Phe Leu Pro Pro Gly Trp Glu Met 
    370                 375                 380                 


Arg Ile Ala Pro Asn Gly Arg Pro Phe Phe Ile Asp His Asn Thr Lys 
385                 390                 395                 400 


Thr Thr Thr Trp Glu Asp Pro Arg Leu Lys Phe Pro Val His Met Arg 
                405                 410                 415     


Ser Lys Thr Ser Leu Asn Pro Asn Asp Leu Gly Pro Leu Pro Pro Gly 
            420                 425                 430         


Trp Glu Glu Arg Ile His Leu Asp Gly Arg Thr Phe Tyr Ile Asp His 
        435                 440                 445             


Asn Ser Lys Ile Thr Gln Trp Glu Asp Pro Arg Leu Gln Asn Pro Ala 
    450                 455                 460                 


Ile Thr Gly Pro Ala Val Pro Tyr Ser Arg Glu Phe Lys Gln Lys Tyr 
465                 470                 475                 480 


Asp Tyr Phe Arg Lys Lys Leu Lys Lys Pro Ala Asp Ile Pro Asn Arg 
                485                 490                 495     


Phe Glu Met Lys Leu His Arg Asn Asn Ile Phe Glu Glu Ser Tyr Arg 
            500                 505                 510         


Arg Ile Met Ser Val Lys Arg Pro Asp Val Leu Lys Ala Arg Leu Trp 
        515                 520                 525             


Ile Glu Phe Glu Ser Glu Lys Gly Leu Asp Tyr Gly Gly Val Ala Arg 
    530                 535                 540                 


Glu Trp Phe Phe Leu Leu Ser Lys Glu Met Phe Asn Pro Tyr Tyr Gly 
545                 550                 555                 560 


Leu Phe Glu Tyr Ser Ala Thr Asp Asn Tyr Thr Leu Gln Ile Asn Pro 
                565                 570                 575     


Asn Ser Gly Leu Cys Asn Glu Asp His Leu Ser Tyr Phe Thr Phe Ile 
            580                 585                 590         


Gly Arg Val Ala Gly Leu Ala Val Phe His Gly Lys Leu Leu Asp Gly 
        595                 600                 605             


Phe Phe Ile Arg Pro Phe Tyr Lys Met Met Leu Gly Lys Gln Ile Thr 
    610                 615                 620                 


Leu Asn Asp Met Glu Ser Val Asp Ser Glu Tyr Tyr Asn Ser Leu Lys 
625                 630                 635                 640 


Trp Ile Leu Glu Asn Asp Pro Thr Glu Leu Asp Leu Met Phe Cys Ile 
                645                 650                 655     


Asp Glu Glu Asn Phe Gly Gln Thr Tyr Gln Val Asp Leu Lys Pro Asn 
            660                 665                 670         


Gly Ser Glu Ile Met Val Thr Asn Glu Asn Lys Arg Glu Tyr Ile Asp 
        675                 680                 685             


Leu Val Ile Gln Trp Arg Phe Val Asn Arg Val Gln Lys Gln Met Asn 
    690                 695                 700                 


Ala Phe Leu Glu Gly Phe Thr Glu Leu Leu Pro Ile Asp Leu Ile Lys 
705                 710                 715                 720 


Ile Phe Asp Glu Asn Glu Leu Glu Leu Leu Met Cys Gly Leu Gly Asp 
                725                 730                 735     


Val Asp Val Asn Asp Trp Arg Gln His Ser Ile Tyr Lys Asn Gly Tyr 
            740                 745                 750         


Cys Pro Asn His Pro Val Ile Gln Trp Phe Trp Lys Ala Val Leu Leu 
        755                 760                 765             


Met Asp Ala Glu Lys Arg Ile Arg Leu Leu Gln Phe Val Thr Gly Thr 
    770                 775                 780                 


Ser Arg Val Pro Met Asn Gly Phe Ala Glu Leu Tyr Gly Ser Asn Gly 
785                 790                 795                 800 


Pro Gln Leu Phe Thr Ile Glu Gln Trp Gly Ser Pro Glu Lys Leu Pro 
                805                 810                 815     


Arg Ala His Thr Cys Phe Asn Arg Leu Asp Leu Pro Pro Tyr Glu Thr 
            820                 825                 830         


Phe Glu Asp Leu Arg Glu Lys Leu Leu Met Ala Val Glu Asn Ala Gln 
        835                 840                 845             


Gly Phe Glu Gly Val Asp 
    850                 


<210>  2952
<211>  543
<212>  PRT
<213>  homo sapiens

<400>  2952

Met Ser Ser Phe Ser Tyr Glu Pro Tyr Tyr Ser Thr Ser Tyr Lys Arg 
1               5                   10                  15      


Arg Tyr Val Glu Thr Pro Arg Val His Ile Ser Ser Val Arg Ser Gly 
            20                  25                  30          


Tyr Ser Thr Ala Arg Ser Ala Tyr Ser Ser Tyr Ser Ala Pro Val Ser 
        35                  40                  45              


Ser Ser Leu Ser Val Arg Arg Ser Tyr Ser Ser Ser Ser Gly Ser Leu 
    50                  55                  60                  


Met Pro Ser Leu Glu Asn Leu Asp Leu Ser Gln Val Ala Ala Ile Ser 
65                  70                  75                  80  


Asn Asp Leu Lys Ser Ile Arg Thr Gln Glu Lys Ala Gln Leu Gln Asp 
                85                  90                  95      


Leu Asn Asp Arg Phe Ala Ser Phe Ile Glu Arg Val His Glu Leu Glu 
            100                 105                 110         


Gln Gln Asn Lys Val Leu Glu Ala Glu Leu Leu Val Leu Arg Gln Lys 
        115                 120                 125             


His Ser Glu Pro Ser Arg Phe Arg Ala Leu Tyr Glu Gln Glu Ile Arg 
    130                 135                 140                 


Asp Leu Arg Leu Ala Ala Glu Asp Ala Thr Asn Glu Lys Gln Ala Leu 
145                 150                 155                 160 


Gln Gly Glu Arg Glu Gly Leu Glu Glu Thr Leu Arg Asn Leu Gln Ala 
                165                 170                 175     


Arg Tyr Glu Glu Glu Val Leu Ser Arg Glu Asp Ala Glu Gly Arg Leu 
            180                 185                 190         


Met Glu Ala Arg Lys Gly Ala Asp Glu Ala Ala Leu Ala Arg Ala Glu 
        195                 200                 205             


Leu Glu Lys Arg Ile Asp Ser Leu Met Asp Glu Ile Ser Phe Leu Lys 
    210                 215                 220                 


Lys Val His Glu Glu Glu Ile Ala Glu Leu Gln Ala Gln Ile Gln Tyr 
225                 230                 235                 240 


Ala Gln Ile Ser Val Glu Met Asp Val Thr Lys Pro Asp Leu Ser Ala 
                245                 250                 255     


Ala Leu Lys Asp Ile Arg Ala Gln Tyr Glu Lys Leu Ala Ala Lys Asn 
            260                 265                 270         


Met Gln Asn Ala Glu Glu Trp Phe Lys Ser Arg Phe Thr Val Leu Thr 
        275                 280                 285             


Glu Ser Ala Ala Lys Asn Thr Asp Ala Val Arg Ala Ala Lys Asp Glu 
    290                 295                 300                 


Val Ser Glu Ser Arg Arg Leu Leu Lys Ala Lys Thr Leu Glu Ile Glu 
305                 310                 315                 320 


Ala Cys Arg Gly Met Asn Glu Ala Leu Glu Lys Gln Leu Gln Glu Leu 
                325                 330                 335     


Glu Asp Lys Gln Asn Ala Asp Ile Ser Ala Met Gln Asp Thr Ile Asn 
            340                 345                 350         


Lys Leu Glu Asn Glu Leu Arg Thr Thr Lys Ser Glu Met Ala Arg Tyr 
        355                 360                 365             


Leu Lys Glu Tyr Gln Asp Leu Leu Asn Val Lys Met Ala Leu Asp Ile 
    370                 375                 380                 


Glu Ile Ala Ala Tyr Arg Lys Leu Leu Glu Gly Glu Glu Thr Arg Leu 
385                 390                 395                 400 


Ser Phe Thr Ser Val Gly Ser Ile Thr Ser Gly Tyr Ser Gln Ser Ser 
                405                 410                 415     


Gln Val Phe Gly Arg Ser Ala Tyr Gly Gly Leu Gln Thr Ser Ser Tyr 
            420                 425                 430         


Leu Met Ser Thr Arg Ser Phe Pro Ser Tyr Tyr Thr Ser His Val Gln 
        435                 440                 445             


Glu Glu Gln Ile Glu Val Glu Glu Thr Ile Glu Ala Ala Lys Ala Glu 
    450                 455                 460                 


Glu Ala Lys Asp Glu Pro Pro Ser Glu Gly Glu Ala Glu Glu Glu Glu 
465                 470                 475                 480 


Lys Asp Lys Glu Glu Ala Glu Glu Glu Glu Ala Ala Glu Glu Glu Glu 
                485                 490                 495     


Ala Ala Lys Glu Glu Ser Glu Glu Ala Lys Glu Glu Glu Glu Gly Gly 
            500                 505                 510         


Glu Gly Glu Glu Gly Glu Glu Thr Lys Glu Ala Glu Glu Glu Glu Lys 
        515                 520                 525             


Lys Val Glu Gly Ala Gly Glu Glu Gln Ala Ala Lys Lys Lys Asp 
    530                 535                 540             


<210>  2953
<211>  540
<212>  PRT
<213>  homo sapiens

<400>  2953

Met Ala Arg His Leu Arg Glu Tyr Gln Asp Leu Leu Asn Val Lys Met 
1               5                   10                  15      


Ala Leu Asp Ile Glu Ile Ala Ala Tyr Arg Lys Leu Leu Glu Gly Glu 
            20                  25                  30          


Glu Thr Arg Phe Ser Thr Phe Ala Gly Ser Ile Thr Gly Pro Leu Tyr 
        35                  40                  45              


Thr His Arg Pro Pro Ile Thr Ile Ser Ser Lys Ile Gln Lys Pro Lys 
    50                  55                  60                  


Val Glu Ala Pro Lys Leu Lys Val Gln His Lys Phe Val Glu Glu Ile 
65                  70                  75                  80  


Ile Glu Glu Thr Lys Val Glu Asp Glu Lys Ser Glu Met Glu Glu Ala 
                85                  90                  95      


Leu Thr Ala Ile Thr Glu Glu Leu Ala Val Ser Met Lys Glu Glu Lys 
            100                 105                 110         


Lys Glu Ala Ala Glu Glu Lys Glu Glu Glu Pro Glu Ala Glu Glu Glu 
        115                 120                 125             


Glu Val Ala Ala Lys Lys Ser Pro Val Lys Ala Thr Ala Pro Glu Val 
    130                 135                 140                 


Lys Glu Glu Glu Gly Glu Lys Glu Glu Glu Glu Gly Gln Glu Glu Glu 
145                 150                 155                 160 


Glu Glu Glu Asp Glu Gly Ala Lys Ser Asp Gln Ala Glu Glu Gly Gly 
                165                 170                 175     


Ser Glu Lys Glu Gly Ser Ser Glu Lys Glu Glu Gly Glu Gln Glu Glu 
            180                 185                 190         


Gly Glu Thr Glu Ala Glu Ala Glu Gly Glu Glu Ala Glu Ala Lys Glu 
        195                 200                 205             


Glu Lys Lys Val Glu Glu Lys Ser Glu Glu Val Ala Thr Lys Glu Glu 
    210                 215                 220                 


Leu Val Ala Asp Ala Lys Val Glu Lys Pro Glu Lys Ala Lys Ser Pro 
225                 230                 235                 240 


Val Pro Lys Ser Pro Val Glu Glu Lys Gly Lys Ser Pro Val Pro Lys 
                245                 250                 255     


Ser Pro Val Glu Glu Lys Gly Lys Ser Pro Val Pro Lys Ser Pro Val 
            260                 265                 270         


Glu Glu Lys Gly Lys Ser Pro Val Pro Lys Ser Pro Val Glu Glu Lys 
        275                 280                 285             


Gly Lys Ser Pro Val Ser Lys Ser Pro Val Glu Glu Lys Ala Lys Ser 
    290                 295                 300                 


Pro Val Pro Lys Ser Pro Val Glu Glu Ala Lys Ser Lys Ala Glu Val 
305                 310                 315                 320 


Gly Lys Gly Glu Gln Lys Glu Glu Glu Glu Lys Glu Val Lys Glu Ala 
                325                 330                 335     


Pro Lys Glu Glu Lys Val Glu Lys Lys Glu Glu Lys Pro Lys Asp Val 
            340                 345                 350         


Pro Glu Lys Lys Lys Ala Glu Ser Pro Val Lys Glu Glu Ala Val Ala 
        355                 360                 365             


Glu Val Val Thr Ile Thr Lys Ser Val Lys Val His Leu Glu Lys Glu 
    370                 375                 380                 


Thr Lys Glu Glu Gly Lys Pro Leu Gln Gln Glu Lys Glu Lys Glu Lys 
385                 390                 395                 400 


Ala Gly Gly Glu Gly Gly Ser Glu Glu Glu Gly Ser Asp Lys Gly Ala 
                405                 410                 415     


Lys Gly Ser Arg Lys Glu Asp Ile Ala Val Asn Gly Glu Val Glu Gly 
            420                 425                 430         


Lys Glu Glu Val Glu Gln Glu Thr Lys Glu Lys Gly Ser Gly Arg Glu 
        435                 440                 445             


Glu Glu Lys Gly Val Val Thr Asn Gly Leu Asp Leu Ser Pro Ala Asp 
    450                 455                 460                 


Glu Lys Lys Gly Gly Asp Lys Ser Glu Glu Lys Val Val Val Thr Lys 
465                 470                 475                 480 


Thr Val Glu Lys Ile Thr Ser Glu Gly Gly Asp Gly Ala Thr Lys Tyr 
                485                 490                 495     


Ile Thr Lys Ser Val Thr Val Thr Gln Lys Val Glu Glu His Glu Glu 
            500                 505                 510         


Thr Phe Glu Glu Lys Leu Val Ser Thr Lys Lys Val Glu Lys Val Thr 
        515                 520                 525             


Ser His Ala Ile Val Lys Glu Val Thr Gln Ser Asp 
    530                 535                 540 


<210>  2954
<211>  777
<212>  PRT
<213>  homo sapiens

<400>  2954

Met Asp Ser Lys Glu Ser Leu Thr Pro Gly Arg Glu Glu Asn Pro Ser 
1               5                   10                  15      


Ser Val Leu Ala Gln Glu Arg Gly Asp Val Met Asp Phe Tyr Lys Thr 
            20                  25                  30          


Leu Arg Gly Gly Ala Thr Val Lys Val Ser Ala Ser Ser Pro Ser Leu 
        35                  40                  45              


Ala Val Ala Ser Gln Ser Asp Ser Lys Gln Arg Arg Leu Leu Val Asp 
    50                  55                  60                  


Phe Pro Lys Gly Ser Val Ser Asn Ala Gln Gln Pro Asp Leu Ser Lys 
65                  70                  75                  80  


Ala Val Ser Leu Ser Met Gly Leu Tyr Met Gly Glu Thr Glu Thr Lys 
                85                  90                  95      


Val Met Gly Asn Asp Leu Gly Phe Pro Gln Gln Gly Gln Ile Ser Leu 
            100                 105                 110         


Ser Ser Gly Glu Thr Asp Leu Lys Leu Leu Glu Glu Ser Ile Ala Asn 
        115                 120                 125             


Leu Asn Arg Ser Thr Ser Val Pro Glu Asn Pro Lys Ser Ser Ala Ser 
    130                 135                 140                 


Thr Ala Val Ser Ala Ala Pro Thr Glu Lys Glu Phe Pro Lys Thr His 
145                 150                 155                 160 


Ser Asp Val Ser Ser Glu Gln Gln His Leu Lys Gly Gln Thr Gly Thr 
                165                 170                 175     


Asn Gly Gly Asn Val Lys Leu Tyr Thr Thr Asp Gln Ser Thr Phe Asp 
            180                 185                 190         


Ile Leu Gln Asp Leu Glu Phe Ser Ser Gly Ser Pro Gly Lys Glu Thr 
        195                 200                 205             


Asn Glu Ser Pro Trp Arg Ser Asp Leu Leu Ile Asp Glu Asn Cys Leu 
    210                 215                 220                 


Leu Ser Pro Leu Ala Gly Glu Asp Asp Ser Phe Leu Leu Glu Gly Asn 
225                 230                 235                 240 


Ser Asn Glu Asp Cys Lys Pro Leu Ile Leu Pro Asp Thr Lys Pro Lys 
                245                 250                 255     


Ile Lys Asp Asn Gly Asp Leu Val Leu Ser Ser Pro Ser Asn Val Thr 
            260                 265                 270         


Leu Pro Gln Val Lys Thr Glu Lys Glu Asp Phe Ile Glu Leu Cys Thr 
        275                 280                 285             


Pro Gly Val Ile Lys Gln Glu Lys Leu Gly Thr Val Tyr Cys Gln Ala 
    290                 295                 300                 


Ser Phe Pro Gly Ala Asn Ile Ile Gly Asn Lys Met Ser Ala Ile Ser 
305                 310                 315                 320 


Val His Gly Val Ser Thr Ser Gly Gly Gln Met Tyr His Tyr Asp Met 
                325                 330                 335     


Asn Thr Ala Ser Leu Ser Gln Gln Gln Asp Gln Lys Pro Ile Phe Asn 
            340                 345                 350         


Val Ile Pro Pro Ile Pro Val Gly Ser Glu Asn Trp Asn Arg Cys Gln 
        355                 360                 365             


Gly Ser Gly Asp Asp Asn Leu Thr Ser Leu Gly Thr Leu Asn Phe Pro 
    370                 375                 380                 


Gly Arg Thr Val Phe Ser Asn Gly Tyr Ser Ser Pro Ser Met Arg Pro 
385                 390                 395                 400 


Asp Val Ser Ser Pro Pro Ser Ser Ser Ser Thr Ala Thr Thr Gly Pro 
                405                 410                 415     


Pro Pro Lys Leu Cys Leu Val Cys Ser Asp Glu Ala Ser Gly Cys His 
            420                 425                 430         


Tyr Gly Val Leu Thr Cys Gly Ser Cys Lys Val Phe Phe Lys Arg Ala 
        435                 440                 445             


Val Glu Gly Gln His Asn Tyr Leu Cys Ala Gly Arg Asn Asp Cys Ile 
    450                 455                 460                 


Ile Asp Lys Ile Arg Arg Lys Asn Cys Pro Ala Cys Arg Tyr Arg Lys 
465                 470                 475                 480 


Cys Leu Gln Ala Gly Met Asn Leu Glu Ala Arg Lys Thr Lys Lys Lys 
                485                 490                 495     


Ile Lys Gly Ile Gln Gln Ala Thr Thr Gly Val Ser Gln Glu Thr Ser 
            500                 505                 510         


Glu Asn Pro Gly Asn Lys Thr Ile Val Pro Ala Thr Leu Pro Gln Leu 
        515                 520                 525             


Thr Pro Thr Leu Val Ser Leu Leu Glu Val Ile Glu Pro Glu Val Leu 
    530                 535                 540                 


Tyr Ala Gly Tyr Asp Ser Ser Val Pro Asp Ser Thr Trp Arg Ile Met 
545                 550                 555                 560 


Thr Thr Leu Asn Met Leu Gly Gly Arg Gln Val Ile Ala Ala Val Lys 
                565                 570                 575     


Trp Ala Lys Ala Ile Pro Gly Phe Arg Asn Leu His Leu Asp Asp Gln 
            580                 585                 590         


Met Thr Leu Leu Gln Tyr Ser Trp Met Phe Leu Met Ala Phe Ala Leu 
        595                 600                 605             


Gly Trp Arg Ser Tyr Arg Gln Ser Ser Ala Asn Leu Leu Cys Phe Ala 
    610                 615                 620                 


Pro Asp Leu Ile Ile Asn Glu Gln Arg Met Thr Leu Pro Cys Met Tyr 
625                 630                 635                 640 


Asp Gln Cys Lys His Met Leu Tyr Val Ser Ser Glu Leu His Arg Leu 
                645                 650                 655     


Gln Val Ser Tyr Glu Glu Tyr Leu Cys Met Lys Thr Leu Leu Leu Leu 
            660                 665                 670         


Ser Ser Val Pro Lys Asp Gly Leu Lys Ser Gln Glu Leu Phe Asp Glu 
        675                 680                 685             


Ile Arg Met Thr Tyr Ile Lys Glu Leu Gly Lys Ala Ile Val Lys Arg 
    690                 695                 700                 


Glu Gly Asn Ser Ser Gln Asn Trp Gln Arg Phe Tyr Gln Leu Thr Lys 
705                 710                 715                 720 


Leu Leu Asp Ser Met His Glu Val Val Glu Asn Leu Leu Asn Tyr Cys 
                725                 730                 735     


Phe Gln Thr Phe Leu Asp Lys Thr Met Ser Ile Glu Phe Pro Glu Met 
            740                 745                 750         


Leu Ala Glu Ile Ile Thr Asn Gln Ile Pro Lys Tyr Ser Asn Gly Asn 
        755                 760                 765             


Ile Lys Lys Leu Leu Phe His Gln Lys 
    770                 775         


<210>  2955
<211>  777
<212>  PRT
<213>  homo sapiens

<400>  2955

Met Asp Ser Lys Glu Ser Leu Thr Pro Gly Arg Glu Glu Asn Pro Ser 
1               5                   10                  15      


Ser Val Leu Ala Gln Glu Arg Gly Asp Val Met Asp Phe Tyr Lys Thr 
            20                  25                  30          


Leu Arg Gly Gly Ala Thr Val Lys Val Ser Ala Ser Ser Pro Ser Leu 
        35                  40                  45              


Ala Val Ala Ser Gln Ser Asp Ser Lys Gln Arg Arg Leu Leu Val Asp 
    50                  55                  60                  


Phe Pro Lys Gly Ser Val Ser Asn Ala Gln Gln Pro Asp Leu Ser Lys 
65                  70                  75                  80  


Ala Val Ser Leu Ser Met Gly Leu Tyr Met Gly Glu Thr Glu Thr Lys 
                85                  90                  95      


Val Met Gly Asn Asp Leu Gly Phe Pro Gln Gln Gly Gln Ile Ser Leu 
            100                 105                 110         


Ser Ser Gly Glu Thr Asp Leu Lys Leu Leu Glu Glu Ser Ile Ala Asn 
        115                 120                 125             


Leu Asn Arg Ser Thr Ser Val Pro Glu Asn Pro Lys Ser Ser Ala Ser 
    130                 135                 140                 


Thr Ala Val Ser Ala Ala Pro Thr Glu Lys Glu Phe Pro Lys Thr His 
145                 150                 155                 160 


Ser Asp Val Ser Ser Glu Gln Gln His Leu Lys Gly Gln Thr Gly Thr 
                165                 170                 175     


Asn Gly Gly Asn Val Lys Leu Tyr Thr Thr Asp Gln Ser Thr Phe Asp 
            180                 185                 190         


Ile Leu Gln Asp Leu Glu Phe Ser Ser Gly Ser Pro Gly Lys Glu Thr 
        195                 200                 205             


Asn Glu Ser Pro Trp Arg Ser Asp Leu Leu Ile Asp Glu Asn Cys Leu 
    210                 215                 220                 


Leu Ser Pro Leu Ala Gly Glu Asp Asp Ser Phe Leu Leu Glu Gly Asn 
225                 230                 235                 240 


Ser Asn Glu Asp Cys Lys Pro Leu Ile Leu Pro Asp Thr Lys Pro Lys 
                245                 250                 255     


Ile Lys Asp Asn Gly Asp Leu Val Leu Ser Ser Pro Ser Asn Val Thr 
            260                 265                 270         


Leu Pro Gln Val Lys Thr Glu Lys Glu Asp Phe Ile Glu Leu Cys Thr 
        275                 280                 285             


Pro Gly Val Ile Lys Gln Glu Lys Leu Gly Thr Val Tyr Cys Gln Ala 
    290                 295                 300                 


Ser Phe Pro Gly Ala Asn Ile Ile Gly Asn Lys Met Ser Ala Ile Ser 
305                 310                 315                 320 


Val His Gly Val Ser Thr Ser Gly Gly Gln Met Tyr His Tyr Asp Met 
                325                 330                 335     


Asn Thr Ala Ser Leu Ser Gln Gln Gln Asp Gln Lys Pro Ile Phe Asn 
            340                 345                 350         


Val Ile Pro Pro Ile Pro Val Gly Ser Glu Asn Trp Asn Arg Cys Gln 
        355                 360                 365             


Gly Ser Gly Asp Asp Asn Leu Thr Ser Leu Gly Thr Leu Asn Phe Pro 
    370                 375                 380                 


Gly Arg Thr Val Phe Ser Asn Gly Tyr Ser Ser Pro Ser Met Arg Pro 
385                 390                 395                 400 


Asp Val Ser Ser Pro Pro Ser Ser Ser Ser Thr Ala Thr Thr Gly Pro 
                405                 410                 415     


Pro Pro Lys Leu Cys Leu Val Cys Ser Asp Glu Ala Ser Gly Cys His 
            420                 425                 430         


Tyr Gly Val Leu Thr Cys Gly Ser Cys Lys Val Phe Phe Lys Arg Ala 
        435                 440                 445             


Val Glu Gly Gln His Asn Tyr Leu Cys Ala Gly Arg Asn Asp Cys Ile 
    450                 455                 460                 


Ile Asp Lys Ile Arg Arg Lys Asn Cys Pro Ala Cys Arg Tyr Arg Lys 
465                 470                 475                 480 


Cys Leu Gln Ala Gly Met Asn Leu Glu Ala Arg Lys Thr Lys Lys Lys 
                485                 490                 495     


Ile Lys Gly Ile Gln Gln Ala Thr Thr Gly Val Ser Gln Glu Thr Ser 
            500                 505                 510         


Glu Asn Pro Gly Asn Lys Thr Ile Val Pro Ala Thr Leu Pro Gln Leu 
        515                 520                 525             


Thr Pro Thr Leu Val Ser Leu Leu Glu Val Ile Glu Pro Glu Val Leu 
    530                 535                 540                 


Tyr Ala Gly Tyr Asp Ser Ser Val Pro Asp Ser Thr Trp Arg Ile Met 
545                 550                 555                 560 


Thr Thr Leu Asn Met Leu Gly Gly Arg Gln Val Ile Ala Ala Val Lys 
                565                 570                 575     


Trp Ala Lys Ala Ile Pro Gly Phe Arg Asn Leu His Leu Asp Asp Gln 
            580                 585                 590         


Met Thr Leu Leu Gln Tyr Ser Trp Met Phe Leu Met Ala Phe Ala Leu 
        595                 600                 605             


Gly Trp Arg Ser Tyr Arg Gln Ser Ser Ala Asn Leu Leu Cys Phe Ala 
    610                 615                 620                 


Pro Asp Leu Ile Ile Asn Glu Gln Arg Met Thr Leu Pro Cys Met Tyr 
625                 630                 635                 640 


Asp Gln Cys Lys His Met Leu Tyr Val Ser Ser Glu Leu His Arg Leu 
                645                 650                 655     


Gln Val Ser Tyr Glu Glu Tyr Leu Cys Met Lys Thr Leu Leu Leu Leu 
            660                 665                 670         


Ser Ser Val Pro Lys Asp Gly Leu Lys Ser Gln Glu Leu Phe Asp Glu 
        675                 680                 685             


Ile Arg Met Thr Tyr Ile Lys Glu Leu Gly Lys Ala Ile Val Lys Arg 
    690                 695                 700                 


Glu Gly Asn Ser Ser Gln Asn Trp Gln Arg Phe Tyr Gln Leu Thr Lys 
705                 710                 715                 720 


Leu Leu Asp Ser Met His Glu Val Val Glu Asn Leu Leu Asn Tyr Cys 
                725                 730                 735     


Phe Gln Thr Phe Leu Asp Lys Thr Met Ser Ile Glu Phe Pro Glu Met 
            740                 745                 750         


Leu Ala Glu Ile Ile Thr Asn Gln Ile Pro Lys Tyr Ser Asn Gly Asn 
        755                 760                 765             


Ile Lys Lys Leu Leu Phe His Gln Lys 
    770                 775         


<210>  2956
<211>  242
<212>  PRT
<213>  homo sapiens

<400>  2956

Met Gly Leu Leu Glu Cys Cys Ala Arg Cys Leu Val Gly Ala Pro Phe 
1               5                   10                  15      


Ala Ser Leu Val Ala Thr Gly Leu Cys Phe Phe Gly Val Ala Leu Phe 
            20                  25                  30          


Cys Gly Cys Gly His Glu Ala Leu Thr Gly Thr Glu Lys Leu Ile Glu 
        35                  40                  45              


Thr Tyr Phe Ser Lys Asn Tyr Gln Asp Tyr Glu Tyr Leu Ile Asn Val 
    50                  55                  60                  


Ile His Ala Phe Gln Tyr Val Ile Tyr Gly Thr Ala Ser Phe Phe Phe 
65                  70                  75                  80  


Leu Tyr Gly Ala Leu Leu Leu Ala Glu Gly Phe Tyr Thr Thr Gly Ala 
                85                  90                  95      


Val Arg Gln Ile Phe Gly Asp Tyr Lys Thr Thr Ile Cys Gly Lys Gly 
            100                 105                 110         


Leu Ser Ala Thr Phe Val Gly Ile Thr Tyr Ala Leu Thr Val Val Trp 
        115                 120                 125             


Leu Leu Val Phe Ala Cys Ser Ala Val Pro Val Tyr Ile Tyr Phe Asn 
    130                 135                 140                 


Thr Trp Thr Thr Cys Gln Ser Ile Ala Phe Pro Ser Lys Thr Ser Ala 
145                 150                 155                 160 


Ser Ile Gly Ser Leu Cys Ala Asp Ala Arg Met Tyr Gly Val Leu Pro 
                165                 170                 175     


Trp Asn Ala Phe Pro Gly Lys Val Cys Gly Ser Asn Leu Leu Ser Ile 
            180                 185                 190         


Cys Lys Thr Ala Glu Phe Gln Met Thr Phe His Leu Phe Ile Ala Ala 
        195                 200                 205             


Phe Val Gly Ala Ala Ala Thr Leu Val Ser Leu Leu Thr Phe Met Ile 
    210                 215                 220                 


Ala Ala Thr Tyr Asn Phe Ala Val Leu Lys Leu Met Gly Arg Gly Thr 
225                 230                 235                 240 


Lys Phe 
        


<210>  2957
<211>  195
<212>  PRT
<213>  homo sapiens

<400>  2957

Met Met Ala Ile Arg Glu Leu Lys Val Cys Leu Leu Gly Asp Thr Gly 
1               5                   10                  15      


Val Gly Lys Ser Ser Ile Val Cys Arg Phe Val Gln Asp His Phe Asp 
            20                  25                  30          


His Asn Ile Ser Pro Thr Ile Gly Ala Ser Phe Met Thr Lys Thr Val 
        35                  40                  45              


Pro Cys Gly Asn Glu Leu His Lys Phe Leu Ile Trp Asp Thr Ala Gly 
    50                  55                  60                  


Gln Glu Arg Phe His Ser Leu Ala Pro Met Tyr Tyr Arg Gly Ser Ala 
65                  70                  75                  80  


Ala Ala Val Ile Val Tyr Asp Ile Thr Lys Gln Asp Ser Phe Tyr Thr 
                85                  90                  95      


Leu Lys Lys Trp Val Lys Glu Leu Lys Glu His Gly Pro Glu Asn Ile 
            100                 105                 110         


Val Met Ala Ile Ala Gly Asn Lys Cys Asp Leu Ser Asp Ile Arg Glu 
        115                 120                 125             


Val Pro Leu Lys Asp Ala Lys Glu Tyr Ala Glu Ser Ile Gly Ala Ile 
    130                 135                 140                 


Val Val Glu Thr Ser Ala Lys Asn Ala Ile Asn Ile Glu Glu Leu Phe 
145                 150                 155                 160 


Gln Gly Ile Ser Arg Gln Ile Pro Pro Leu Asp Pro His Glu Asn Gly 
                165                 170                 175     


Asn Asn Gly Thr Ile Lys Val Glu Lys Pro Thr Met Gln Ala Ser Arg 
            180                 185                 190         


Arg Cys Cys 
        195 


<210>  2958
<211>  706
<212>  PRT
<213>  homo sapiens

<400>  2958

Met Ala Ser Pro Ala Asp Ser Cys Ile Gln Phe Thr Arg His Ala Ser 
1               5                   10                  15      


Asp Val Leu Leu Asn Leu Asn Arg Leu Arg Ser Arg Asp Ile Leu Thr 
            20                  25                  30          


Asp Val Val Ile Val Val Ser Arg Glu Gln Phe Arg Ala His Lys Thr 
        35                  40                  45              


Val Leu Met Ala Cys Ser Gly Leu Phe Tyr Ser Ile Phe Thr Asp Gln 
    50                  55                  60                  


Leu Lys Cys Asn Leu Ser Val Ile Asn Leu Asp Pro Glu Ile Asn Pro 
65                  70                  75                  80  


Glu Gly Phe Cys Ile Leu Leu Asp Phe Met Tyr Thr Ser Arg Leu Asn 
                85                  90                  95      


Leu Arg Glu Gly Asn Ile Met Ala Val Met Ala Thr Ala Met Tyr Leu 
            100                 105                 110         


Gln Met Glu His Val Val Asp Thr Cys Arg Lys Phe Ile Lys Ala Ser 
        115                 120                 125             


Glu Ala Glu Met Val Ser Ala Ile Lys Pro Pro Arg Glu Glu Phe Leu 
    130                 135                 140                 


Asn Ser Arg Met Leu Met Pro Gln Asp Ile Met Ala Tyr Arg Gly Arg 
145                 150                 155                 160 


Glu Val Val Glu Asn Asn Leu Pro Leu Arg Ser Ala Pro Gly Cys Glu 
                165                 170                 175     


Ser Arg Ala Phe Ala Pro Ser Leu Tyr Ser Gly Leu Ser Thr Pro Pro 
            180                 185                 190         


Ala Ser Tyr Ser Met Tyr Ser His Leu Pro Val Ser Ser Leu Leu Phe 
        195                 200                 205             


Ser Asp Glu Glu Phe Arg Asp Val Arg Met Pro Val Ala Asn Pro Phe 
    210                 215                 220                 


Pro Lys Glu Arg Ala Leu Pro Cys Asp Ser Ala Arg Pro Val Pro Gly 
225                 230                 235                 240 


Glu Tyr Ser Arg Pro Thr Leu Glu Val Ser Pro Asn Val Cys His Ser 
                245                 250                 255     


Asn Ile Tyr Ser Pro Lys Glu Thr Ile Pro Glu Glu Ala Arg Ser Asp 
            260                 265                 270         


Met His Tyr Ser Val Ala Glu Gly Leu Lys Pro Ala Ala Pro Ser Ala 
        275                 280                 285             


Arg Asn Ala Pro Tyr Phe Pro Cys Asp Lys Ala Ser Lys Glu Glu Glu 
    290                 295                 300                 


Arg Pro Ser Ser Glu Asp Glu Ile Ala Leu His Phe Glu Pro Pro Asn 
305                 310                 315                 320 


Ala Pro Leu Asn Arg Lys Gly Leu Val Ser Pro Gln Ser Pro Gln Lys 
                325                 330                 335     


Ser Asp Cys Gln Pro Asn Ser Pro Thr Glu Ser Cys Ser Ser Lys Asn 
            340                 345                 350         


Ala Cys Ile Leu Gln Ala Ser Gly Ser Pro Pro Ala Lys Ser Pro Thr 
        355                 360                 365             


Asp Pro Lys Ala Cys Asn Trp Lys Lys Tyr Lys Phe Ile Val Leu Asn 
    370                 375                 380                 


Ser Leu Asn Gln Asn Ala Lys Pro Glu Gly Pro Glu Gln Ala Glu Leu 
385                 390                 395                 400 


Gly Arg Leu Ser Pro Arg Ala Tyr Thr Ala Pro Pro Ala Cys Gln Pro 
                405                 410                 415     


Pro Met Glu Pro Glu Asn Leu Asp Leu Gln Ser Pro Thr Lys Leu Ser 
            420                 425                 430         


Ala Ser Gly Glu Asp Ser Thr Ile Pro Gln Ala Ser Arg Leu Asn Asn 
        435                 440                 445             


Ile Val Asn Arg Ser Met Thr Gly Ser Pro Arg Ser Ser Ser Glu Ser 
    450                 455                 460                 


His Ser Pro Leu Tyr Met His Pro Pro Lys Cys Thr Ser Cys Gly Ser 
465                 470                 475                 480 


Gln Ser Pro Gln His Ala Glu Met Cys Leu His Thr Ala Gly Pro Thr 
                485                 490                 495     


Phe Pro Glu Glu Met Gly Glu Thr Gln Ser Glu Tyr Ser Asp Ser Ser 
            500                 505                 510         


Cys Glu Asn Gly Ala Phe Phe Cys Asn Glu Cys Asp Cys Arg Phe Ser 
        515                 520                 525             


Glu Glu Ala Ser Leu Lys Arg His Thr Leu Gln Thr His Ser Asp Lys 
    530                 535                 540                 


Pro Tyr Lys Cys Asp Arg Cys Gln Ala Ser Phe Arg Tyr Lys Gly Asn 
545                 550                 555                 560 


Leu Ala Ser His Lys Thr Val His Thr Gly Glu Lys Pro Tyr Arg Cys 
                565                 570                 575     


Asn Ile Cys Gly Ala Gln Phe Asn Arg Pro Ala Asn Leu Lys Thr His 
            580                 585                 590         


Thr Arg Ile His Ser Gly Glu Lys Pro Tyr Lys Cys Glu Thr Cys Gly 
        595                 600                 605             


Ala Arg Phe Val Gln Val Ala His Leu Arg Ala His Val Leu Ile His 
    610                 615                 620                 


Thr Gly Glu Lys Pro Tyr Pro Cys Glu Ile Cys Gly Thr Arg Phe Arg 
625                 630                 635                 640 


His Leu Gln Thr Leu Lys Ser His Leu Arg Ile His Thr Gly Glu Lys 
                645                 650                 655     


Pro Tyr His Cys Glu Lys Cys Asn Leu His Phe Arg His Lys Ser Gln 
            660                 665                 670         


Leu Arg Leu His Leu Arg Gln Lys His Gly Ala Ile Thr Asn Thr Lys 
        675                 680                 685             


Val Gln Tyr Arg Val Ser Ala Thr Asp Leu Pro Pro Glu Leu Pro Lys 
    690                 695                 700                 


Ala Cys 
705     


<210>  2959
<211>  272
<212>  PRT
<213>  homo sapiens

<400>  2959

Met Phe Val Lys Ser Glu Thr Leu Glu Leu Lys Glu Glu Glu Asp Val 
1               5                   10                  15      


Leu Val Leu Leu Gly Ser Ala Ser Pro Ala Leu Ala Ala Leu Thr Pro 
            20                  25                  30          


Leu Ser Ser Ser Ala Asp Glu Glu Glu Glu Glu Glu Pro Gly Ala Ser 
        35                  40                  45              


Gly Gly Ala Arg Arg Gln Arg Gly Ala Glu Ala Gly Gln Gly Ala Arg 
    50                  55                  60                  


Gly Gly Val Ala Ala Gly Ala Glu Gly Cys Arg Pro Ala Arg Leu Leu 
65                  70                  75                  80  


Gly Leu Val His Asp Cys Lys Arg Arg Pro Ser Arg Ala Arg Ala Val 
                85                  90                  95      


Ser Arg Gly Ala Lys Thr Ala Glu Thr Val Gln Arg Ile Lys Lys Thr 
            100                 105                 110         


Arg Arg Leu Lys Ala Asn Asn Arg Glu Arg Asn Arg Met His Asn Leu 
        115                 120                 125             


Asn Ala Ala Leu Asp Ala Leu Arg Glu Val Leu Pro Thr Phe Pro Glu 
    130                 135                 140                 


Asp Ala Lys Leu Thr Lys Ile Glu Thr Leu Arg Phe Ala His Asn Tyr 
145                 150                 155                 160 


Ile Trp Ala Leu Thr Glu Thr Leu Arg Leu Ala Asp His Cys Gly Gly 
                165                 170                 175     


Gly Gly Gly Gly Leu Pro Gly Ala Leu Phe Ser Glu Ala Val Leu Leu 
            180                 185                 190         


Ser Pro Gly Gly Ala Ser Ala Ala Leu Ser Ser Ser Gly Asp Ser Pro 
        195                 200                 205             


Ser Pro Ala Ser Thr Trp Ser Cys Thr Asn Ser Pro Ala Pro Ser Ser 
    210                 215                 220                 


Ser Val Ser Ser Asn Ser Thr Ser Pro Tyr Ser Cys Thr Leu Ser Pro 
225                 230                 235                 240 


Ala Ser Pro Ala Gly Ser Asp Met Asp Tyr Trp Gln Pro Pro Pro Pro 
                245                 250                 255     


Asp Lys His Arg Tyr Ala Pro His Leu Pro Ile Ala Arg Asp Cys Ile 
            260                 265                 270         


<210>  2960
<211>  1321
<212>  PRT
<213>  homo sapiens

<400>  2960

Met Gly Ala Pro Phe Val Trp Ala Leu Gly Leu Leu Met Leu Gln Met 
1               5                   10                  15      


Leu Leu Phe Val Ala Gly Glu Gln Gly Thr Gln Asp Ile Thr Asp Ala 
            20                  25                  30          


Ser Glu Arg Gly Leu His Met Gln Lys Leu Gly Ser Gly Ser Val Gln 
        35                  40                  45              


Ala Ala Leu Ala Glu Leu Val Ala Leu Pro Cys Leu Phe Thr Leu Gln 
    50                  55                  60                  


Pro Arg Pro Ser Ala Ala Arg Asp Ala Pro Arg Ile Lys Trp Thr Lys 
65                  70                  75                  80  


Val Arg Thr Ala Ser Gly Gln Arg Gln Asp Leu Pro Ile Leu Val Ala 
                85                  90                  95      


Lys Asp Asn Val Val Arg Val Ala Lys Ser Trp Gln Gly Arg Val Ser 
            100                 105                 110         


Leu Pro Ser Tyr Pro Arg Arg Arg Ala Asn Ala Thr Leu Leu Leu Gly 
        115                 120                 125             


Pro Leu Arg Ala Ser Asp Ser Gly Leu Tyr Arg Cys Gln Val Val Arg 
    130                 135                 140                 


Gly Ile Glu Asp Glu Gln Asp Leu Val Pro Leu Glu Val Thr Gly Val 
145                 150                 155                 160 


Val Phe His Tyr Arg Ser Ala Arg Asp Arg Tyr Ala Leu Thr Phe Ala 
                165                 170                 175     


Glu Ala Gln Glu Ala Cys Arg Leu Ser Ser Ala Ile Ile Ala Ala Pro 
            180                 185                 190         


Arg His Leu Gln Ala Ala Phe Glu Asp Gly Phe Asp Asn Cys Asp Ala 
        195                 200                 205             


Gly Trp Leu Ser Asp Arg Thr Val Arg Tyr Pro Ile Thr Gln Ser Arg 
    210                 215                 220                 


Pro Gly Cys Tyr Gly Asp Arg Ser Ser Leu Pro Gly Val Arg Ser Tyr 
225                 230                 235                 240 


Gly Arg Arg Asn Pro Gln Glu Leu Tyr Asp Val Tyr Cys Phe Ala Arg 
                245                 250                 255     


Glu Leu Gly Gly Glu Val Phe Tyr Val Gly Pro Ala Arg Arg Leu Thr 
            260                 265                 270         


Leu Ala Gly Ala Arg Ala Gln Cys Arg Arg Gln Gly Ala Ala Leu Ala 
        275                 280                 285             


Ser Val Gly Gln Leu His Leu Ala Trp His Glu Gly Leu Asp Gln Cys 
    290                 295                 300                 


Asp Pro Gly Trp Leu Ala Asp Gly Ser Val Arg Tyr Pro Ile Gln Thr 
305                 310                 315                 320 


Pro Arg Arg Arg Cys Gly Gly Pro Ala Pro Gly Val Arg Thr Val Tyr 
                325                 330                 335     


Arg Phe Ala Asn Arg Thr Gly Phe Pro Ser Pro Ala Glu Arg Phe Asp 
            340                 345                 350         


Ala Tyr Cys Phe Arg Ala His His Pro Thr Ser Gln His Gly Asp Leu 
        355                 360                 365             


Glu Thr Pro Ser Ser Gly Asp Glu Gly Glu Ile Leu Ser Ala Glu Gly 
    370                 375                 380                 


Pro Pro Val Arg Glu Leu Glu Pro Thr Leu Glu Glu Glu Glu Val Val 
385                 390                 395                 400 


Thr Pro Asp Phe Gln Glu Pro Leu Val Ser Ser Gly Glu Glu Glu Thr 
                405                 410                 415     


Leu Ile Leu Glu Glu Lys Gln Glu Ser Gln Gln Thr Leu Ser Pro Thr 
            420                 425                 430         


Pro Gly Asp Pro Met Leu Ala Ser Trp Pro Thr Gly Glu Val Trp Leu 
        435                 440                 445             


Ser Thr Val Ala Pro Ser Pro Ser Asp Met Gly Ala Gly Thr Ala Ala 
    450                 455                 460                 


Ser Ser His Thr Glu Val Ala Pro Thr Asp Pro Met Pro Arg Arg Arg 
465                 470                 475                 480 


Gly Arg Phe Lys Gly Leu Asn Gly Arg Tyr Phe Gln Gln Gln Glu Pro 
                485                 490                 495     


Glu Pro Gly Leu Gln Gly Gly Met Glu Ala Ser Ala Gln Pro Pro Thr 
            500                 505                 510         


Ser Glu Ala Ala Val Asn Gln Met Glu Pro Pro Leu Ala Met Ala Val 
        515                 520                 525             


Thr Glu Met Leu Gly Ser Gly Gln Ser Arg Ser Pro Trp Ala Asp Leu 
    530                 535                 540                 


Thr Asn Glu Val Asp Met Pro Gly Ala Gly Ser Ala Gly Gly Lys Ser 
545                 550                 555                 560 


Ser Pro Glu Pro Trp Leu Trp Pro Pro Thr Met Val Pro Pro Ser Ile 
                565                 570                 575     


Ser Gly His Ser Arg Ala Pro Val Leu Glu Leu Glu Lys Ala Glu Gly 
            580                 585                 590         


Pro Ser Ala Arg Pro Ala Thr Pro Asp Leu Phe Trp Ser Pro Leu Glu 
        595                 600                 605             


Ala Thr Val Ser Ala Pro Ser Pro Ala Pro Trp Glu Ala Phe Pro Val 
    610                 615                 620                 


Ala Thr Ser Pro Asp Leu Pro Met Met Ala Met Leu Arg Gly Pro Lys 
625                 630                 635                 640 


Glu Trp Met Leu Pro His Pro Thr Pro Ile Ser Thr Glu Ala Asn Arg 
                645                 650                 655     


Val Glu Ala His Gly Glu Ala Thr Ala Thr Ala Pro Pro Ser Pro Ala 
            660                 665                 670         


Ala Glu Thr Lys Val Tyr Ser Leu Pro Leu Ser Leu Thr Pro Thr Gly 
        675                 680                 685             


Gln Gly Gly Glu Ala Met Pro Thr Thr Pro Glu Ser Pro Arg Ala Asp 
    690                 695                 700                 


Phe Arg Glu Thr Gly Glu Thr Ser Pro Ala Gln Val Asn Lys Ala Glu 
705                 710                 715                 720 


His Ser Ser Ser Ser Pro Trp Pro Ser Val Asn Arg Asn Val Ala Val 
                725                 730                 735     


Gly Phe Val Pro Thr Glu Thr Ala Thr Glu Pro Thr Gly Leu Arg Gly 
            740                 745                 750         


Ile Pro Gly Ser Glu Ser Gly Val Phe Asp Thr Ala Glu Ser Pro Thr 
        755                 760                 765             


Ser Gly Leu Gln Ala Thr Val Asp Glu Val Gln Asp Pro Trp Pro Ser 
    770                 775                 780                 


Val Tyr Ser Lys Gly Leu Asp Ala Ser Ser Pro Ser Ala Pro Leu Gly 
785                 790                 795                 800 


Ser Pro Gly Val Phe Leu Val Pro Lys Val Thr Pro Asn Leu Glu Pro 
                805                 810                 815     


Trp Val Ala Thr Asp Glu Gly Pro Thr Val Asn Pro Met Asp Ser Thr 
            820                 825                 830         


Val Thr Pro Ala Pro Ser Asp Ala Ser Gly Ile Trp Glu Pro Gly Ser 
        835                 840                 845             


Gln Val Phe Glu Glu Ala Glu Ser Thr Thr Leu Ser Pro Gln Val Ala 
    850                 855                 860                 


Leu Asp Thr Ser Ile Val Thr Pro Leu Thr Thr Leu Glu Gln Gly Asp 
865                 870                 875                 880 


Lys Val Gly Val Pro Ala Met Ser Thr Leu Gly Ser Ser Ser Ser Gln 
                885                 890                 895     


Pro His Pro Glu Pro Glu Asp Gln Val Glu Thr Gln Gly Thr Ser Gly 
            900                 905                 910         


Ala Ser Val Pro Pro His Gln Ser Ser Pro Leu Gly Lys Pro Ala Val 
        915                 920                 925             


Pro Pro Gly Thr Pro Thr Ala Ala Ser Val Gly Glu Ser Ala Ser Val 
    930                 935                 940                 


Ser Ser Gly Glu Pro Thr Val Pro Trp Asp Pro Ser Ser Thr Leu Leu 
945                 950                 955                 960 


Pro Val Thr Leu Gly Ile Glu Asp Phe Glu Leu Glu Val Leu Ala Gly 
                965                 970                 975     


Ser Pro Gly Val Glu Ser Phe Trp Glu Glu Val Ala Ser Gly Glu Glu 
            980                 985                 990         


Pro Ala Leu Pro Gly Thr Pro Met  Asn Ala Gly Ala Glu  Glu Val His 
        995                 1000                 1005             


Ser Asp  Pro Cys Glu Asn Asn  Pro Cys Leu His Gly  Gly Thr Cys 
    1010                 1015                 1020             


Asn Ala  Asn Gly Thr Met Tyr  Gly Cys Ser Cys Asp  Gln Gly Phe 
    1025                 1030                 1035             


Ala Gly  Glu Asn Cys Glu Ile  Asp Ile Asp Asp Cys  Leu Cys Ser 
    1040                 1045                 1050             


Pro Cys  Glu Asn Gly Gly Thr  Cys Ile Asp Glu Val  Asn Gly Phe 
    1055                 1060                 1065             


Val Cys  Leu Cys Leu Pro Ser  Tyr Gly Gly Ser Phe  Cys Glu Lys 
    1070                 1075                 1080             


Asp Thr  Glu Gly Cys Asp Arg  Gly Trp His Lys Phe  Gln Gly His 
    1085                 1090                 1095             


Cys Tyr  Arg Tyr Phe Ala His  Arg Arg Ala Trp Glu  Asp Ala Glu 
    1100                 1105                 1110             


Lys Asp  Cys Arg Arg Arg Ser  Gly His Leu Thr Ser  Val His Ser 
    1115                 1120                 1125             


Pro Glu  Glu His Ser Phe Ile  Asn Ser Phe Gly His  Glu Asn Thr 
    1130                 1135                 1140             


Trp Ile  Gly Leu Asn Asp Arg  Ile Val Glu Arg Asp  Phe Gln Trp 
    1145                 1150                 1155             


Thr Asp  Asn Thr Gly Leu Gln  Phe Glu Asn Trp Arg  Glu Asn Gln 
    1160                 1165                 1170             


Pro Asp  Asn Phe Phe Ala Gly  Gly Glu Asp Cys Val  Val Met Val 
    1175                 1180                 1185             


Ala His  Glu Ser Gly Arg Trp  Asn Asp Val Pro Cys  Asn Tyr Asn 
    1190                 1195                 1200             


Leu Pro  Tyr Val Cys Lys Lys  Gly Thr Val Leu Cys  Gly Pro Pro 
    1205                 1210                 1215             


Pro Ala  Val Glu Asn Ala Ser  Leu Ile Gly Ala Arg  Lys Ala Lys 
    1220                 1225                 1230             


Tyr Asn  Val His Ala Thr Val  Arg Tyr Gln Cys Asn  Glu Gly Phe 
    1235                 1240                 1245             


Ala Gln  His His Val Ala Thr  Ile Arg Cys Arg Ser  Asn Gly Lys 
    1250                 1255                 1260             


Trp Asp  Arg Pro Gln Ile Val  Cys Thr Lys Pro Arg  Arg Ser His 
    1265                 1270                 1275             


Arg Met  Arg Arg His His His  His His Gln His His  His Gln His 
    1280                 1285                 1290             


His His  His Lys Ser Arg Lys  Glu Arg Arg Lys His  Lys Lys His 
    1295                 1300                 1305             


Pro Thr  Glu Asp Trp Glu Lys  Asp Glu Gly Asn Phe  Cys 
    1310                 1315                 1320     


<210>  2961
<211>  357
<212>  PRT
<213>  homo sapiens

<400>  2961

Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Pro Gly Gln Thr Pro Glu Ala Ala Lys Thr His Ser Val Glu Thr Pro 
            20                  25                  30          


Tyr Gly Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg 
        35                  40                  45              


Pro Ala Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys 
    50                  55                  60                  


Phe Gln Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn 
65                  70                  75                  80  


Phe Val Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro 
                85                  90                  95      


Val Phe Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp 
            100                 105                 110         


Met Ile Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly 
        115                 120                 125             


Val Gly Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn 
    130                 135                 140                 


His Pro Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn 
145                 150                 155                 160 


Ala Lys Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr 
                165                 170                 175     


Ser Ser Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu 
            180                 185                 190         


Leu Ser Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr 
        195                 200                 205             


His Ala Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn 
    210                 215                 220                 


Asn Arg Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg 
225                 230                 235                 240 


Cys Pro Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala 
                245                 250                 255     


Val Val Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu 
            260                 265                 270         


Lys Met Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Gln Pro Gly Lys 
        275                 280                 285             


Leu Thr Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr Met Ala 
    290                 295                 300                 


Ser Ser Cys Met Thr Arg Leu Ser Arg Ser Arg Thr Ala Ser Leu Thr 
305                 310                 315                 320 


Ser Ala Ala Ser Val Asp Gly Asn Arg Ser Arg Ser Arg Thr Leu Ser 
                325                 330                 335     


Gln Ser Ser Glu Ser Gly Thr Leu Ser Ser Gly Pro Pro Gly His Thr 
            340                 345                 350         


Met Glu Val Ser Cys 
        355         


<210>  2962
<211>  81
<212>  PRT
<213>  homo sapiens

<400>  2962

Met Gly Gln Leu Cys Cys Phe Pro Phe Ser Arg Asp Glu Gly Lys Ile 
1               5                   10                  15      


Ser Glu Lys Asn Gly Gly Glu Pro Asp Asp Ala Glu Leu Val Arg Leu 
            20                  25                  30          


Ser Lys Arg Leu Val Glu Asn Ala Val Leu Lys Ala Val Gln Gln Tyr 
        35                  40                  45              


Leu Glu Glu Thr Gln Asn Lys Asn Lys Pro Gly Glu Gly Ser Ser Val 
    50                  55                  60                  


Lys Thr Glu Ala Ala Asp Gln Asn Gly Asn Asp Asn Glu Asn Asn Arg 
65                  70                  75                  80  


Lys 
    


<210>  2963
<211>  328
<212>  PRT
<213>  homo sapiens

<400>  2963

Met Ser Ala Ala Gly Leu Leu Ala Pro Ala Pro Ala Gln Ala Gly Ala 
1               5                   10                  15      


Pro Pro Ala Pro Glu Tyr Tyr Pro Glu Glu Asp Glu Glu Leu Glu Ser 
            20                  25                  30          


Ala Glu Asp Asp Glu Arg Ser Cys Arg Gly Arg Glu Ser Asp Glu Asp 
        35                  40                  45              


Thr Glu Asp Ala Ser Glu Thr Asp Leu Ala Lys His Asp Glu Glu Asp 
    50                  55                  60                  


Tyr Val Glu Met Lys Glu Gln Met Tyr Gln Asp Lys Leu Ala Ser Leu 
65                  70                  75                  80  


Lys Arg Gln Leu Gln Gln Leu Gln Glu Gly Thr Leu Gln Glu Tyr Gln 
                85                  90                  95      


Lys Arg Met Lys Lys Leu Asp Gln Gln Tyr Lys Glu Arg Ile Arg Asn 
            100                 105                 110         


Ala Glu Leu Phe Leu Gln Leu Glu Thr Glu Gln Val Glu Arg Asn Tyr 
        115                 120                 125             


Ile Lys Glu Lys Lys Ala Ala Val Lys Glu Phe Glu Asp Lys Lys Val 
    130                 135                 140                 


Glu Leu Lys Glu Asn Leu Ile Ala Glu Leu Glu Glu Lys Lys Lys Met 
145                 150                 155                 160 


Ile Glu Asn Glu Lys Leu Thr Met Glu Leu Thr Gly Asp Ser Met Glu 
                165                 170                 175     


Val Lys Pro Ile Met Thr Arg Lys Leu Arg Arg Arg Pro Asn Asp Pro 
            180                 185                 190         


Val Pro Ile Pro Asp Lys Arg Arg Lys Pro Ala Pro Ala Gln Leu Asn 
        195                 200                 205             


Tyr Leu Leu Thr Asp Glu Gln Ile Met Glu Asp Leu Arg Thr Leu Asn 
    210                 215                 220                 


Lys Leu Lys Ser Pro Lys Arg Pro Ala Ser Pro Ser Ser Pro Glu His 
225                 230                 235                 240 


Leu Pro Ala Thr Pro Ala Glu Ser Pro Ala Gln Arg Phe Glu Ala Arg 
                245                 250                 255     


Ile Glu Asp Gly Lys Leu Tyr Tyr Asp Lys Arg Trp Tyr His Lys Ser 
            260                 265                 270         


Gln Ala Ile Tyr Leu Glu Ser Lys Asp Asn Gln Lys Leu Ser Cys Val 
        275                 280                 285             


Ile Ser Ser Val Gly Ala Asn Glu Ile Trp Val Arg Lys Thr Ser Asp 
    290                 295                 300                 


Ser Thr Lys Met Arg Ile Tyr Leu Gly Gln Leu Gln Arg Gly Leu Phe 
305                 310                 315                 320 


Val Ile Arg Arg Arg Ser Ala Ala 
                325             


<210>  2964
<211>  104
<212>  PRT
<213>  homo sapiens

<400>  2964

Met Gly Gln Leu Cys Cys Phe Pro Phe Ser Arg Asp Glu Gly Lys Ile 
1               5                   10                  15      


Ser Glu Leu Glu Ser Ser Ser Ser Ala Val Leu Gln Arg Tyr Ser Lys 
            20                  25                  30          


Asp Ile Pro Ser Trp Ser Ser Gly Glu Lys Asn Gly Gly Glu Pro Asp 
        35                  40                  45              


Asp Ala Glu Leu Val Arg Leu Ser Lys Arg Leu Val Glu Asn Ala Val 
    50                  55                  60                  


Leu Lys Ala Val Gln Gln Tyr Leu Glu Glu Thr Gln Asn Lys Asn Lys 
65                  70                  75                  80  


Pro Gly Glu Gly Ser Ser Val Lys Thr Glu Ala Ala Asp Gln Asn Gly 
                85                  90                  95      


Asn Asp Asn Glu Asn Asn Arg Lys 
            100                 


<210>  2965
<211>  524
<212>  PRT
<213>  homo sapiens

<400>  2965

Met Thr Ala Glu Asp Ser Thr Ala Ala Met Ser Ser Asp Ser Ala Ala 
1               5                   10                  15      


Gly Ser Ser Ala Lys Val Pro Glu Gly Val Ala Gly Ala Pro Asn Glu 
            20                  25                  30          


Ala Ala Leu Leu Ala Leu Met Glu Arg Thr Gly Tyr Ser Met Val Gln 
        35                  40                  45              


Glu Asn Gly Gln Arg Lys Tyr Gly Gly Pro Pro Pro Gly Trp Glu Gly 
    50                  55                  60                  


Pro His Pro Gln Arg Gly Cys Glu Val Phe Val Gly Lys Ile Pro Arg 
65                  70                  75                  80  


Asp Val Tyr Glu Asp Glu Leu Val Pro Val Phe Glu Ala Val Gly Arg 
                85                  90                  95      


Ile Tyr Glu Leu Arg Leu Met Met Asp Phe Asp Gly Lys Asn Arg Gly 
            100                 105                 110         


Tyr Ala Phe Val Met Tyr Cys His Lys His Glu Ala Lys Arg Ala Val 
        115                 120                 125             


Arg Glu Leu Asn Asn Tyr Glu Ile Arg Pro Gly Arg Leu Leu Gly Val 
    130                 135                 140                 


Cys Cys Ser Val Asp Asn Cys Arg Leu Phe Ile Gly Gly Ile Pro Lys 
145                 150                 155                 160 


Met Lys Lys Arg Glu Glu Ile Leu Glu Glu Ile Ala Lys Val Thr Glu 
                165                 170                 175     


Gly Val Leu Asp Val Ile Val Tyr Ala Ser Ala Ala Asp Lys Met Lys 
            180                 185                 190         


Asn Arg Gly Phe Ala Phe Val Glu Tyr Glu Ser His Arg Ala Ala Ala 
        195                 200                 205             


Met Ala Arg Arg Lys Leu Met Pro Gly Arg Ile Gln Leu Trp Gly His 
    210                 215                 220                 


Gln Ile Ala Val Asp Trp Ala Glu Pro Glu Ile Asp Val Asp Glu Asp 
225                 230                 235                 240 


Val Met Glu Thr Val Lys Ile Leu Tyr Val Arg Asn Leu Met Ile Glu 
                245                 250                 255     


Thr Thr Glu Asp Thr Ile Lys Lys Ser Phe Gly Gln Phe Asn Pro Gly 
            260                 265                 270         


Cys Val Glu Arg Val Lys Lys Ile Arg Asp Tyr Ala Phe Val His Phe 
        275                 280                 285             


Thr Ser Arg Glu Asp Ala Val His Ala Met Asn Asn Leu Asn Gly Thr 
    290                 295                 300                 


Glu Leu Glu Gly Ser Cys Leu Glu Val Thr Leu Ala Lys Pro Val Asp 
305                 310                 315                 320 


Lys Glu Gln Tyr Ser Arg Tyr Gln Lys Ala Ala Arg Gly Gly Gly Ala 
                325                 330                 335     


Ala Glu Ala Ala Gln Gln Pro Ser Tyr Val Tyr Ser Cys Asp Pro Tyr 
            340                 345                 350         


Thr Leu Ala Tyr Tyr Gly Tyr Pro Tyr Asn Ala Leu Ile Gly Pro Asn 
        355                 360                 365             


Arg Asp Tyr Phe Val Lys Val Ala Ile Pro Ala Ile Gly Ala Gln Tyr 
    370                 375                 380                 


Ser Met Phe Pro Ala Ala Pro Ala Pro Lys Met Ile Glu Asp Gly Lys 
385                 390                 395                 400 


Ile His Thr Val Glu His Met Ile Ser Pro Ile Ala Val Gln Pro Asp 
                405                 410                 415     


Pro Ala Ser Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala 
            420                 425                 430         


Ala Val Ile Pro Thr Val Ser Thr Pro Pro Pro Phe Gln Gly Arg Pro 
        435                 440                 445             


Ile Thr Pro Val Tyr Thr Val Ala Pro Asn Val Gln Arg Ile Pro Thr 
    450                 455                 460                 


Ala Gly Ile Tyr Gly Ala Ser Tyr Val Pro Phe Ala Ala Pro Ala Thr 
465                 470                 475                 480 


Ala Thr Ile Ala Thr Leu Gln Lys Asn Ala Ala Ala Ala Ala Ala Met 
                485                 490                 495     


Tyr Gly Gly Tyr Ala Gly Tyr Ile Pro Gln Ala Phe Pro Ala Ala Ala 
            500                 505                 510         


Ile Gln Val Pro Ile Pro Asp Val Tyr Gln Thr Tyr 
        515                 520                 


<210>  2966
<211>  403
<212>  PRT
<213>  homo sapiens

<400>  2966

Met Gly Lys Val Trp Lys Gln Gln Met Tyr Pro Gln Tyr Ala Thr Tyr 
1               5                   10                  15      


Tyr Tyr Pro Gln Tyr Leu Gln Ala Lys Gln Ser Leu Val Pro Ala His 
            20                  25                  30          


Pro Met Ala Pro Pro Ser Pro Ser Thr Thr Ser Ser Asn Asn Asn Ser 
        35                  40                  45              


Ser Ser Ser Ser Asn Ser Gly Trp Asp Gln Leu Ser Lys Thr Asn Leu 
    50                  55                  60                  


Tyr Ile Arg Gly Leu Pro Pro His Thr Thr Asp Gln Asp Leu Val Lys 
65                  70                  75                  80  


Leu Cys Gln Pro Tyr Gly Lys Ile Val Ser Thr Lys Ala Ile Leu Asp 
                85                  90                  95      


Lys Thr Thr Asn Lys Cys Lys Gly Tyr Gly Phe Val Asp Phe Asp Ser 
            100                 105                 110         


Pro Ala Ala Ala Gln Lys Ala Val Ser Ala Leu Lys Ala Ser Gly Val 
        115                 120                 125             


Gln Ala Gln Met Ala Lys Gln Gln Glu Gln Asp Pro Thr Asn Leu Tyr 
    130                 135                 140                 


Ile Ser Asn Leu Pro Leu Ser Met Asp Glu Gln Glu Leu Glu Asn Met 
145                 150                 155                 160 


Leu Lys Pro Phe Gly Gln Val Ile Ser Thr Arg Ile Leu Arg Asp Ser 
                165                 170                 175     


Ser Gly Thr Ser Arg Gly Val Gly Phe Ala Arg Met Glu Ser Thr Glu 
            180                 185                 190         


Lys Cys Glu Ala Val Ile Gly His Phe Asn Gly Lys Phe Ile Lys Thr 
        195                 200                 205             


Pro Pro Gly Val Ser Ala Pro Thr Glu Pro Leu Leu Cys Lys Phe Ala 
    210                 215                 220                 


Asp Gly Gly Gln Lys Lys Arg Gln Asn Pro Asn Lys Tyr Ile Pro Asn 
225                 230                 235                 240 


Gly Arg Pro Trp His Arg Glu Gly Glu Ala Gly Met Thr Leu Thr Tyr 
                245                 250                 255     


Asp Pro Thr Thr Ala Ala Ile Gln Asn Gly Phe Tyr Pro Ser Pro Tyr 
            260                 265                 270         


Ser Ile Ala Thr Asn Arg Met Ile Thr Gln Thr Ser Ile Thr Pro Tyr 
        275                 280                 285             


Ile Ala Ser Pro Val Ser Ala Tyr Gln Val Gln Ser Pro Ser Trp Met 
    290                 295                 300                 


Gln Pro Gln Pro Tyr Ile Leu Gln His Pro Gly Ala Val Leu Thr Pro 
305                 310                 315                 320 


Ser Met Glu His Thr Met Ser Leu Gln Pro Ala Ser Met Ile Ser Pro 
                325                 330                 335     


Leu Ala Gln Gln Met Ser His Leu Ser Leu Gly Ser Thr Gly Thr Tyr 
            340                 345                 350         


Met Pro Ala Thr Ser Ala Met Gln Gly Ala Tyr Leu Pro Gln Tyr Ala 
        355                 360                 365             


His Met Gln Thr Thr Ala Val Pro Val Glu Glu Ala Ser Gly Gln Gln 
    370                 375                 380                 


Gln Val Ala Val Glu Thr Ser Asn Asp His Ser Pro Tyr Thr Phe Gln 
385                 390                 395                 400 


Pro Asn Lys 
            


<210>  2967
<211>  706
<212>  PRT
<213>  homo sapiens

<400>  2967

Met Ala Val Pro Ala Ala Leu Ile Pro Pro Thr Gln Leu Val Pro Pro 
1               5                   10                  15      


Gln Pro Pro Ile Ser Thr Ser Ala Ser Ser Ser Gly Thr Thr Thr Ser 
            20                  25                  30          


Thr Ser Ser Ala Thr Ser Ser Pro Ala Pro Ser Ile Gly Pro Pro Ala 
        35                  40                  45              


Ser Ser Gly Pro Thr Leu Phe Arg Pro Glu Pro Ile Ala Ser Ala Ala 
    50                  55                  60                  


Ala Ala Ala Ala Thr Val Thr Ser Thr Gly Gly Gly Gly Gly Gly Gly 
65                  70                  75                  80  


Gly Ser Gly Gly Gly Gly Gly Ser Ser Gly Asn Gly Gly Gly Gly Gly 
                85                  90                  95      


Gly Gly Gly Gly Gly Ser Asn Cys Asn Pro Asn Leu Ala Ala Ala Ser 
            100                 105                 110         


Asn Gly Ser Gly Gly Gly Gly Gly Gly Ile Ser Ala Gly Gly Gly Val 
        115                 120                 125             


Ala Ser Ser Thr Pro Ile Asn Ala Ser Thr Gly Ser Ser Ser Ser Ser 
    130                 135                 140                 


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser 
145                 150                 155                 160 


Ser Ser Ser Cys Gly Pro Leu Pro Gly Lys Pro Val Tyr Ser Thr Pro 
                165                 170                 175     


Ser Pro Val Glu Asn Thr Pro Gln Asn Asn Glu Cys Lys Met Val Asp 
            180                 185                 190         


Leu Arg Gly Ala Lys Val Ala Ser Phe Thr Val Glu Gly Cys Glu Leu 
        195                 200                 205             


Ile Cys Leu Pro Gln Ala Phe Asp Leu Phe Leu Lys His Leu Val Gly 
    210                 215                 220                 


Gly Leu His Thr Val Tyr Thr Lys Leu Lys Arg Leu Glu Ile Thr Pro 
225                 230                 235                 240 


Val Val Cys Asn Val Glu Gln Val Arg Ile Leu Arg Gly Leu Gly Ala 
                245                 250                 255     


Ile Gln Pro Gly Val Asn Arg Cys Lys Leu Ile Ser Arg Lys Asp Phe 
            260                 265                 270         


Glu Thr Leu Tyr Asn Asp Cys Thr Asn Ala Ser Ser Arg Pro Gly Arg 
        275                 280                 285             


Pro Pro Lys Arg Thr Gln Ser Val Thr Ser Pro Glu Asn Ser His Ile 
    290                 295                 300                 


Met Pro His Ser Val Pro Gly Leu Met Ser Pro Gly Ile Ile Pro Pro 
305                 310                 315                 320 


Thr Gly Leu Thr Ala Ala Ala Ala Ala Ala Ala Ala Ala Thr Asn Ala 
                325                 330                 335     


Ala Ile Ala Glu Ala Met Lys Val Lys Lys Ile Lys Leu Glu Ala Met 
            340                 345                 350         


Ser Asn Tyr His Ala Ser Asn Asn Gln His Gly Ala Asp Ser Glu Asn 
        355                 360                 365             


Gly Asp Met Asn Ser Ser Val Gly Leu Glu Leu Pro Phe Met Met Met 
    370                 375                 380                 


Pro His Pro Leu Ile Pro Val Ser Leu Pro Pro Ala Ser Val Thr Met 
385                 390                 395                 400 


Ala Met Ser Gln Met Asn His Leu Ser Thr Ile Ala Asn Met Ala Ala 
                405                 410                 415     


Ala Ala Gln Val Gln Ser Pro Pro Ser Arg Val Glu Thr Ser Val Ile 
            420                 425                 430         


Lys Glu Arg Val Pro Asp Ser Pro Ser Pro Ala Pro Ser Leu Glu Glu 
        435                 440                 445             


Gly Arg Arg Pro Gly Ser His Pro Ser Ser His Arg Ser Ser Ser Val 
    450                 455                 460                 


Ser Ser Ser Pro Ala Arg Thr Glu Ser Ser Ser Asp Arg Ile Pro Val 
465                 470                 475                 480 


His Gln Asn Gly Leu Ser Met Asn Gln Met Leu Met Gly Leu Ser Pro 
                485                 490                 495     


Asn Val Leu Pro Gly Pro Lys Glu Gly Asp Leu Ala Gly His Asp Met 
            500                 505                 510         


Gly His Glu Ser Lys Arg Met His Ile Glu Lys Asp Glu Thr Pro Leu 
        515                 520                 525             


Ser Thr Pro Thr Ala Arg Asp Ser Leu Asp Lys Leu Ser Leu Thr Gly 
    530                 535                 540                 


His Gly Gln Pro Leu Pro Pro Gly Phe Pro Ser Pro Phe Leu Phe Pro 
545                 550                 555                 560 


Asp Gly Leu Ser Ser Ile Glu Thr Leu Leu Thr Asn Ile Gln Gly Leu 
                565                 570                 575     


Leu Lys Val Ala Ile Asp Asn Ala Arg Ala Gln Glu Lys Gln Val Gln 
            580                 585                 590         


Leu Glu Lys Thr Glu Leu Lys Met Asp Phe Leu Arg Glu Arg Glu Leu 
        595                 600                 605             


Arg Glu Thr Leu Glu Lys Gln Leu Ala Met Glu Gln Lys Asn Arg Ala 
    610                 615                 620                 


Ile Val Gln Lys Arg Leu Lys Lys Glu Lys Lys Ala Lys Arg Lys Leu 
625                 630                 635                 640 


Gln Glu Ala Leu Glu Phe Glu Thr Lys Arg Arg Glu Gln Ala Glu Gln 
                645                 650                 655     


Thr Leu Lys Gln Ala Ala Ser Thr Asp Ser Leu Arg Val Leu Asn Asp 
            660                 665                 670         


Ser Leu Thr Pro Glu Ile Glu Ala Asp Arg Ser Gly Gly Arg Thr Asp 
        675                 680                 685             


Ala Glu Arg Thr Ile Gln Asp Gly Arg Leu Tyr Leu Lys Thr Thr Val 
    690                 695                 700                 


Met Tyr 
705     


<210>  2968
<211>  834
<212>  PRT
<213>  homo sapiens

<400>  2968

Met Glu Arg Pro Tyr Thr Phe Lys Asp Phe Leu Leu Arg Pro Arg Ser 
1               5                   10                  15      


His Lys Ser Arg Val Lys Gly Phe Leu Arg Leu Lys Met Ala Tyr Met 
            20                  25                  30          


Pro Lys Asn Gly Gly Gln Asp Glu Glu Asn Ser Asp Gln Arg Asp Asp 
        35                  40                  45              


Met Glu His Gly Trp Glu Val Val Asp Ser Asn Asp Ser Ala Ser Gln 
    50                  55                  60                  


His Gln Glu Glu Leu Pro Pro Pro Pro Leu Pro Pro Gly Trp Glu Glu 
65                  70                  75                  80  


Lys Val Asp Asn Leu Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg 
                85                  90                  95      


Thr Thr Gln Trp His Arg Pro Ser Leu Met Asp Val Ser Ser Glu Ser 
            100                 105                 110         


Asp Asn Asn Ile Arg Gln Ile Asn Gln Glu Ala Ala His Arg Arg Phe 
        115                 120                 125             


Arg Ser Arg Arg His Ile Ser Glu Asp Leu Glu Pro Glu Pro Ser Glu 
    130                 135                 140                 


Gly Gly Asp Val Pro Glu Pro Trp Glu Thr Ile Ser Glu Glu Val Asn 
145                 150                 155                 160 


Ile Ala Gly Asp Ser Leu Gly Leu Ala Leu Pro Pro Pro Pro Ala Ser 
                165                 170                 175     


Pro Gly Ser Arg Thr Ser Pro Gln Glu Leu Ser Glu Glu Leu Ser Arg 
            180                 185                 190         


Arg Leu Gln Ile Thr Pro Asp Ser Asn Gly Glu Gln Phe Ser Ser Leu 
        195                 200                 205             


Ile Gln Arg Glu Pro Ser Ser Arg Leu Arg Ser Cys Ser Val Thr Asp 
    210                 215                 220                 


Ala Val Ala Glu Gln Gly His Leu Pro Pro Pro Ser Val Ala Tyr Val 
225                 230                 235                 240 


His Thr Thr Pro Gly Leu Pro Ser Gly Trp Glu Glu Arg Lys Asp Ala 
                245                 250                 255     


Lys Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg Thr Thr Thr Trp 
            260                 265                 270         


Thr Arg Pro Ile Met Gln Leu Ala Glu Asp Gly Ala Ser Gly Ser Ala 
        275                 280                 285             


Thr Asn Ser Asn Asn His Leu Ile Glu Pro Gln Ile Arg Arg Pro Arg 
    290                 295                 300                 


Ser Leu Ser Ser Pro Thr Val Thr Leu Ser Ala Pro Leu Glu Gly Ala 
305                 310                 315                 320 


Lys Asp Ser Pro Val Arg Arg Ala Val Lys Asp Thr Leu Ser Asn Pro 
                325                 330                 335     


Gln Ser Pro Gln Pro Ser Pro Tyr Asn Ser Pro Lys Pro Gln His Lys 
            340                 345                 350         


Val Thr Gln Ser Phe Leu Pro Pro Gly Trp Glu Met Arg Ile Ala Pro 
        355                 360                 365             


Asn Gly Arg Pro Phe Phe Ile Asp His Asn Thr Lys Thr Thr Thr Trp 
    370                 375                 380                 


Glu Asp Pro Arg Leu Lys Phe Pro Val His Met Arg Ser Lys Thr Ser 
385                 390                 395                 400 


Leu Asn Pro Asn Asp Leu Gly Pro Leu Pro Pro Gly Trp Glu Glu Arg 
                405                 410                 415     


Ile His Leu Asp Gly Arg Thr Phe Tyr Ile Asp His Asn Ser Lys Ile 
            420                 425                 430         


Thr Gln Trp Glu Asp Pro Arg Leu Gln Asn Pro Ala Ile Thr Gly Pro 
        435                 440                 445             


Ala Val Pro Tyr Ser Arg Glu Phe Lys Gln Lys Tyr Asp Tyr Phe Arg 
    450                 455                 460                 


Lys Lys Leu Lys Lys Pro Ala Asp Ile Pro Asn Arg Phe Glu Met Lys 
465                 470                 475                 480 


Leu His Arg Asn Asn Ile Phe Glu Glu Ser Tyr Arg Arg Ile Met Ser 
                485                 490                 495     


Val Lys Arg Pro Asp Val Leu Lys Ala Arg Leu Trp Ile Glu Phe Glu 
            500                 505                 510         


Ser Glu Lys Gly Leu Asp Tyr Gly Gly Val Ala Arg Glu Trp Phe Phe 
        515                 520                 525             


Leu Leu Ser Lys Glu Met Phe Asn Pro Tyr Tyr Gly Leu Phe Glu Tyr 
    530                 535                 540                 


Ser Ala Thr Asp Asn Tyr Thr Leu Gln Ile Asn Pro Asn Ser Gly Leu 
545                 550                 555                 560 


Cys Asn Glu Asp His Leu Ser Tyr Phe Thr Phe Ile Gly Arg Val Ala 
                565                 570                 575     


Gly Leu Ala Val Phe His Gly Lys Leu Leu Asp Gly Phe Phe Ile Arg 
            580                 585                 590         


Pro Phe Tyr Lys Met Met Leu Gly Lys Gln Ile Thr Leu Asn Asp Met 
        595                 600                 605             


Glu Ser Val Asp Ser Glu Tyr Tyr Asn Ser Leu Lys Trp Ile Leu Glu 
    610                 615                 620                 


Asn Asp Pro Thr Glu Leu Asp Leu Met Phe Cys Ile Asp Glu Glu Asn 
625                 630                 635                 640 


Phe Gly Gln Thr Tyr Gln Val Asp Leu Lys Pro Asn Gly Ser Glu Ile 
                645                 650                 655     


Met Val Thr Asn Glu Asn Lys Arg Glu Tyr Ile Asp Leu Val Ile Gln 
            660                 665                 670         


Trp Arg Phe Val Asn Arg Val Gln Lys Gln Met Asn Ala Phe Leu Glu 
        675                 680                 685             


Gly Phe Thr Glu Leu Leu Pro Ile Asp Leu Ile Lys Ile Phe Asp Glu 
    690                 695                 700                 


Asn Glu Leu Glu Leu Leu Met Cys Gly Leu Gly Asp Val Asp Val Asn 
705                 710                 715                 720 


Asp Trp Arg Gln His Ser Ile Tyr Lys Asn Gly Tyr Cys Pro Asn His 
                725                 730                 735     


Pro Val Ile Gln Trp Phe Trp Lys Ala Val Leu Leu Met Asp Ala Glu 
            740                 745                 750         


Lys Arg Ile Arg Leu Leu Gln Phe Val Thr Gly Thr Ser Arg Val Pro 
        755                 760                 765             


Met Asn Gly Phe Ala Glu Leu Tyr Gly Ser Asn Gly Pro Gln Leu Phe 
    770                 775                 780                 


Thr Ile Glu Gln Trp Gly Ser Pro Glu Lys Leu Pro Arg Ala His Thr 
785                 790                 795                 800 


Cys Phe Asn Arg Leu Asp Leu Pro Pro Tyr Glu Thr Phe Glu Asp Leu 
                805                 810                 815     


Arg Glu Lys Leu Leu Met Ala Val Glu Asn Ala Gln Gly Phe Glu Gly 
            820                 825                 830         


Val Asp 
        


<210>  2969
<211>  178
<212>  PRT
<213>  homo sapiens

<400>  2969

Met Ser Glu Val Ser Cys Lys Lys Arg Asp Asp Tyr Leu Glu Trp Pro 
1               5                   10                  15      


Glu Tyr Phe Met Ala Val Ala Phe Leu Ser Ala Gln Arg Ser Lys Asp 
            20                  25                  30          


Pro Asn Ser Gln Val Gly Ala Cys Ile Val Asn Ser Glu Asn Lys Ile 
        35                  40                  45              


Val Gly Ile Gly Tyr Asn Gly Met Pro Asn Gly Cys Ser Asp Asp Val 
    50                  55                  60                  


Leu Pro Trp Arg Arg Thr Ala Glu Asn Lys Leu Asp Thr Lys Tyr Pro 
65                  70                  75                  80  


Tyr Val Cys His Ala Glu Leu Asn Ala Ile Met Asn Lys Asn Ser Thr 
                85                  90                  95      


Asp Val Lys Gly Cys Ser Met Tyr Val Ala Leu Phe Pro Cys Asn Glu 
            100                 105                 110         


Cys Ala Lys Leu Ile Ile Gln Ala Gly Ile Lys Glu Val Ile Phe Met 
        115                 120                 125             


Ser Asp Lys Tyr His Asp Ser Asp Glu Ala Thr Ala Ala Arg Leu Leu 
    130                 135                 140                 


Phe Asn Met Ala Gly Val Thr Phe Arg Lys Phe Ile Pro Lys Cys Ser 
145                 150                 155                 160 


Lys Ile Val Ile Asp Phe Asp Ser Ile Asn Ser Arg Pro Ser Gln Lys 
                165                 170                 175     


Leu Gln 
        


<210>  2970
<211>  284
<212>  PRT
<213>  homo sapiens

<400>  2970

Met Trp Arg Gly Leu Ala Leu Ala Arg Ala Ile Gly Cys Ala Ala Arg 
1               5                   10                  15      


Gly Arg Gly Gln Trp Ala Val Arg Ala Ala Asp Cys Ala Gln Ser Gly 
            20                  25                  30          


Arg His Pro Gly Pro Ala Val Val Cys Gly Arg Arg Leu Ile Ser Val 
        35                  40                  45              


Leu Glu Gln Ile Arg His Phe Val Met Met Pro Glu Ile Asn Thr Asn 
    50                  55                  60                  


His Leu Asp Lys Gln Gln Val Gln Leu Leu Ala Glu Met Cys Ile Leu 
65                  70                  75                  80  


Ile Asp Glu Asn Asp Asn Lys Ile Gly Ala Glu Thr Lys Lys Asn Cys 
                85                  90                  95      


His Leu Asn Glu Asn Ile Glu Lys Gly Leu Leu His Arg Ala Phe Ser 
            100                 105                 110         


Val Phe Leu Phe Asn Thr Glu Asn Lys Leu Leu Leu Gln Gln Arg Ser 
        115                 120                 125             


Asp Ala Lys Ile Thr Phe Pro Gly Cys Phe Thr Asn Thr Cys Cys Ser 
    130                 135                 140                 


His Pro Leu Ser Asn Pro Ala Glu Leu Glu Glu Ser Asp Ala Leu Gly 
145                 150                 155                 160 


Val Arg Arg Ala Ala Gln Arg Arg Leu Lys Ala Glu Leu Gly Ile Pro 
                165                 170                 175     


Leu Glu Glu Val Pro Pro Glu Glu Ile Asn Tyr Leu Thr Arg Ile His 
            180                 185                 190         


Tyr Lys Ala Gln Ser Asp Gly Ile Trp Gly Glu His Glu Ile Asp Tyr 
        195                 200                 205             


Ile Leu Leu Val Arg Lys Asn Val Thr Leu Asn Pro Asp Pro Asn Glu 
    210                 215                 220                 


Ile Lys Ser Tyr Cys Tyr Val Ser Lys Glu Glu Leu Lys Glu Leu Leu 
225                 230                 235                 240 


Lys Lys Ala Ala Ser Gly Glu Ile Lys Ile Thr Pro Trp Phe Lys Ile 
                245                 250                 255     


Ile Ala Ala Thr Phe Leu Phe Lys Trp Trp Asp Asn Leu Asn His Leu 
            260                 265                 270         


Asn Gln Phe Val Asp His Glu Lys Ile Tyr Arg Met 
        275                 280                 


<210>  2971
<211>  223
<212>  PRT
<213>  homo sapiens

<400>  2971

Met Glu Val Gln Lys Glu Ala Gln Arg Ile Met Thr Leu Ser Val Trp 
1               5                   10                  15      


Lys Met Tyr His Ser Arg Met Gln Arg Gly Gly Leu Arg Leu His Arg 
            20                  25                  30          


Ser Leu Gln Leu Ser Leu Val Met Arg Ser Ala Arg Glu Leu Tyr Leu 
        35                  40                  45              


Ser Ala Lys Val Glu Ala Leu Glu Pro Glu Val Ser Leu Pro Ala Ala 
    50                  55                  60                  


Leu Pro Ser Asp Pro Arg Leu His Pro Pro Arg Glu Ala Glu Ser Thr 
65                  70                  75                  80  


Ala Glu Thr Ala Thr Pro Asp Gly Glu His Pro Phe Pro Glu Pro Met 
                85                  90                  95      


Asp Thr Gln Glu Ala Pro Thr Ala Glu Glu Thr Ser Ala Cys Cys Ala 
            100                 105                 110         


Pro Arg Pro Ala Lys Val Ser Arg Lys Arg Arg Ser Ser Ser Leu Ser 
        115                 120                 125             


Asp Gly Gly Asp Ala Gly Leu Val Pro Ser Lys Lys Ala Arg Leu Glu 
    130                 135                 140                 


Glu Lys Glu Glu Glu Glu Gly Ala Ser Ser Glu Val Ala Asp Arg Leu 
145                 150                 155                 160 


Gln Pro Pro Pro Ala Gln Ala Glu Gly Ala Phe Pro Asn Leu Ala Arg 
                165                 170                 175     


Val Leu Gln Arg Arg Phe Ser Gly Leu Leu Asn Cys Ser Pro Ala Ala 
            180                 185                 190         


Pro Pro Thr Ala Pro Pro Ala Cys Glu Ala Lys Pro Ala Cys Arg Pro 
        195                 200                 205             


Ala Asp Ser Met Leu Asn Val Leu Val Arg Ala Val Val Ala Phe 
    210                 215                 220             


<210>  2972
<211>  486
<212>  PRT
<213>  homo sapiens

<400>  2972

Met Ala Trp Ile Lys Arg Lys Phe Gly Glu Arg Pro Pro Pro Lys Arg 
1               5                   10                  15      


Leu Thr Arg Glu Ala Met Arg Asn Tyr Leu Lys Glu Arg Gly Asp Gln 
            20                  25                  30          


Thr Val Leu Ile Leu His Ala Lys Val Ala Gln Lys Ser Tyr Gly Asn 
        35                  40                  45              


Glu Lys Arg Phe Phe Cys Pro Pro Pro Cys Val Tyr Leu Met Gly Ser 
    50                  55                  60                  


Gly Trp Lys Lys Lys Lys Glu Gln Met Glu Arg Asp Gly Cys Ser Glu 
65                  70                  75                  80  


Gln Glu Ser Gln Pro Cys Ala Phe Ile Gly Ile Gly Asn Ser Asp Gln 
                85                  90                  95      


Glu Met Gln Gln Leu Asn Leu Glu Gly Lys Asn Tyr Cys Thr Ala Lys 
            100                 105                 110         


Thr Leu Tyr Ile Ser Asp Ser Asp Lys Arg Lys His Phe Met Leu Ser 
        115                 120                 125             


Val Lys Met Phe Tyr Gly Asn Ser Asp Asp Ile Gly Val Phe Leu Ser 
    130                 135                 140                 


Lys Arg Ile Lys Val Ile Ser Lys Pro Ser Lys Lys Lys Gln Ser Leu 
145                 150                 155                 160 


Lys Asn Ala Asp Leu Cys Ile Ala Ser Gly Thr Lys Val Ala Leu Phe 
                165                 170                 175     


Asn Arg Leu Arg Ser Gln Thr Val Ser Thr Arg Tyr Leu His Val Glu 
            180                 185                 190         


Gly Gly Asn Phe His Ala Ser Ser Gln Gln Trp Gly Ala Phe Phe Ile 
        195                 200                 205             


His Leu Leu Asp Asp Asp Glu Ser Glu Gly Glu Glu Phe Thr Val Arg 
    210                 215                 220                 


Asp Gly Tyr Ile His Tyr Gly Gln Thr Val Lys Leu Val Cys Ser Val 
225                 230                 235                 240 


Thr Gly Met Ala Leu Pro Arg Leu Ile Ile Arg Lys Val Asp Lys Gln 
                245                 250                 255     


Thr Ala Leu Leu Asp Ala Asp Asp Pro Val Ser Gln Leu His Lys Cys 
            260                 265                 270         


Ala Phe Tyr Leu Lys Asp Thr Glu Arg Met Tyr Leu Cys Leu Ser Gln 
        275                 280                 285             


Glu Arg Ile Ile Gln Phe Gln Ala Thr Pro Cys Pro Lys Glu Pro Asn 
    290                 295                 300                 


Lys Glu Met Ile Asn Asp Gly Ala Ser Trp Thr Ile Ile Ser Thr Asp 
305                 310                 315                 320 


Lys Ala Glu Tyr Thr Phe Tyr Glu Gly Met Gly Pro Val Leu Ala Pro 
                325                 330                 335     


Val Thr Pro Val Pro Val Val Glu Ser Leu Gln Leu Asn Gly Gly Gly 
            340                 345                 350         


Asp Val Ala Met Leu Glu Leu Thr Gly Gln Asn Phe Thr Pro Asn Leu 
        355                 360                 365             


Arg Val Trp Phe Gly Asp Val Glu Ala Glu Thr Met Tyr Arg Cys Gly 
    370                 375                 380                 


Glu Ser Met Leu Cys Val Val Pro Asp Ile Ser Ala Phe Arg Glu Gly 
385                 390                 395                 400 


Trp Arg Trp Val Arg Gln Pro Val Gln Val Pro Val Thr Leu Val Arg 
                405                 410                 415     


Asn Asp Gly Ile Ile Tyr Ser Thr Ser Leu Thr Phe Thr Tyr Thr Pro 
            420                 425                 430         


Glu Pro Gly Pro Arg Pro His Cys Ser Ala Ala Gly Ala Ile Leu Arg 
        435                 440                 445             


Ala Asn Ser Ser Gln Val Pro Pro Asn Glu Ser Asn Thr Asn Ser Glu 
    450                 455                 460                 


Gly Ser Tyr Thr Asn Ala Ser Thr Asn Ser Thr Ser Val Thr Ser Ser 
465                 470                 475                 480 


Thr Ala Thr Val Val Ser 
                485     


<210>  2973
<211>  449
<212>  PRT
<213>  homo sapiens

<400>  2973

Met Met Leu Ser Thr Glu Gly Arg Glu Gly Phe Val Val Lys Val Arg 
1               5                   10                  15      


Gly Leu Pro Trp Ser Cys Ser Ala Asp Glu Val Met Arg Phe Phe Ser 
            20                  25                  30          


Asp Cys Lys Ile Gln Asn Gly Thr Ser Gly Ile Arg Phe Ile Tyr Thr 
        35                  40                  45              


Arg Glu Gly Arg Pro Ser Gly Glu Ala Phe Val Glu Leu Glu Ser Glu 
    50                  55                  60                  


Glu Glu Val Lys Leu Ala Leu Lys Lys Asp Arg Glu Thr Met Gly His 
65                  70                  75                  80  


Arg Tyr Val Glu Val Phe Lys Ser Asn Ser Val Glu Met Asp Trp Val 
                85                  90                  95      


Leu Lys His Thr Gly Pro Asn Ser Pro Asp Thr Ala Asn Asp Gly Phe 
            100                 105                 110         


Val Arg Leu Arg Gly Leu Pro Phe Gly Cys Ser Lys Glu Glu Ile Val 
        115                 120                 125             


Gln Phe Phe Ser Gly Leu Glu Ile Val Pro Asn Gly Met Thr Leu Pro 
    130                 135                 140                 


Val Asp Phe Gln Gly Arg Ser Thr Gly Glu Ala Phe Val Gln Phe Ala 
145                 150                 155                 160 


Ser Gln Glu Ile Ala Glu Lys Ala Leu Lys Lys His Lys Glu Arg Ile 
                165                 170                 175     


Gly His Arg Tyr Ile Glu Ile Phe Lys Ser Ser Arg Ala Glu Val Arg 
            180                 185                 190         


Thr His Tyr Asp Pro Pro Arg Lys Leu Met Ala Met Gln Arg Pro Gly 
        195                 200                 205             


Pro Tyr Asp Arg Pro Gly Ala Gly Arg Gly Tyr Asn Ser Ile Gly Arg 
    210                 215                 220                 


Gly Ala Gly Phe Glu Arg Met Arg Arg Gly Ala Tyr Gly Gly Gly Tyr 
225                 230                 235                 240 


Gly Gly Tyr Asp Asp Tyr Gly Gly Tyr Asn Asp Gly Tyr Gly Phe Gly 
                245                 250                 255     


Ser Asp Arg Phe Gly Arg Asp Leu Asn Tyr Cys Phe Ser Gly Met Ser 
            260                 265                 270         


Asp His Arg Tyr Gly Asp Gly Gly Ser Ser Phe Gln Ser Thr Thr Gly 
        275                 280                 285             


His Cys Val His Met Arg Gly Leu Pro Tyr Arg Ala Thr Glu Asn Asp 
    290                 295                 300                 


Ile Tyr Asn Phe Phe Ser Pro Leu Asn Pro Met Arg Val His Ile Glu 
305                 310                 315                 320 


Ile Gly Pro Asp Gly Arg Val Thr Gly Glu Ala Asp Val Glu Phe Ala 
                325                 330                 335     


Thr His Glu Asp Ala Val Ala Ala Met Ala Lys Asp Lys Ala Asn Met 
            340                 345                 350         


Gln His Arg Tyr Val Glu Leu Phe Leu Asn Ser Thr Ala Gly Thr Ser 
        355                 360                 365             


Gly Gly Ala Tyr Asp His Ser Tyr Val Glu Leu Phe Leu Asn Ser Thr 
    370                 375                 380                 


Ala Gly Ala Ser Gly Gly Ala Tyr Gly Ser Gln Met Met Gly Gly Met 
385                 390                 395                 400 


Gly Leu Ser Asn Gln Ser Ser Tyr Gly Gly Pro Ala Ser Gln Gln Leu 
                405                 410                 415     


Ser Gly Gly Tyr Gly Gly Gly Tyr Gly Gly Gln Ser Ser Met Ser Gly 
            420                 425                 430         


Tyr Asp Gln Val Leu Gln Glu Asn Ser Ser Asp Tyr Gln Ser Asn Leu 
        435                 440                 445             


Ala 
    


<210>  2974
<211>  348
<212>  PRT
<213>  homo sapiens

<400>  2974

Met Glu Arg Pro Glu Ala Gly Gly Ile Asn Ser Asn Glu Cys Glu Asn 
1               5                   10                  15      


Val Ser Arg Lys Lys Lys Met Ser Glu Glu Phe Glu Ala Asn Thr Met 
            20                  25                  30          


Asp Ser Leu Val Asp Met Pro Phe Ala Thr Val Asp Ile Gln Asp Asp 
        35                  40                  45              


Cys Gly Ile Thr Asp Glu Pro Gln Ile Asn Leu Lys Arg Ser Gln Glu 
    50                  55                  60                  


Asn Glu Trp Val Lys Ser Asp Gln Val Lys Lys Arg Lys Lys Lys Arg 
65                  70                  75                  80  


Lys Asp Tyr Gln Pro Asn Tyr Phe Leu Ser Ile Pro Ile Thr Asn Lys 
                85                  90                  95      


Glu Ile Ile Lys Gly Ile Lys Ile Leu Gln Asn Ala Ile Ile Gln Gln 
            100                 105                 110         


Asp Glu Arg Leu Ala Lys Ala Met Val Ser Asp Gly Ser Phe His Ile 
        115                 120                 125             


Thr Leu Leu Val Met Gln Leu Leu Asn Glu Asp Glu Val Asn Ile Gly 
    130                 135                 140                 


Ile Asp Ala Leu Leu Glu Leu Lys Pro Phe Ile Glu Glu Leu Leu Gln 
145                 150                 155                 160 


Gly Lys His Leu Thr Leu Pro Phe Gln Gly Ile Gly Thr Phe Gly Asn 
                165                 170                 175     


Gln Val Gly Phe Val Lys Leu Ala Glu Gly Asp His Val Asn Ser Leu 
            180                 185                 190         


Leu Glu Ile Ala Glu Thr Ala Asn Arg Thr Phe Gln Glu Lys Gly Ile 
        195                 200                 205             


Leu Val Gly Glu Ser Arg Ser Phe Lys Pro His Leu Thr Phe Met Lys 
    210                 215                 220                 


Leu Ser Lys Ser Pro Trp Leu Arg Lys Asn Gly Val Lys Lys Ile Asp 
225                 230                 235                 240 


Pro Asp Leu Tyr Glu Lys Phe Ile Ser His Arg Phe Gly Glu Glu Ile 
                245                 250                 255     


Leu Tyr Arg Ile Asp Leu Cys Ser Met Leu Lys Lys Lys Gln Ser Asn 
            260                 265                 270         


Gly Tyr Tyr His Cys Glu Ser Ser Ile Val Ile Gly Glu Lys Asn Gly 
        275                 280                 285             


Gly Glu Pro Asp Asp Ala Glu Leu Val Arg Leu Ser Lys Arg Leu Val 
    290                 295                 300                 


Glu Asn Ala Val Leu Lys Ala Val Gln Gln Tyr Leu Glu Glu Thr Gln 
305                 310                 315                 320 


Asn Lys Asn Lys Pro Gly Glu Gly Ser Ser Val Lys Thr Glu Ala Ala 
                325                 330                 335     


Asp Gln Asn Gly Asn Asp Asn Glu Asn Asn Arg Lys 
            340                 345             


<210>  2975
<211>  45
<212>  PRT
<213>  homo sapiens

<400>  2975

Met Ser Asp Lys Pro Asp Leu Ser Glu Val Glu Lys Phe Asp Arg Ser 
1               5                   10                  15      


Lys Leu Lys Lys Thr Asn Thr Glu Glu Lys Asn Thr Leu Pro Ser Lys 
            20                  25                  30          


Glu Thr Ile Gln Gln Glu Lys Glu Cys Val Gln Thr Ser 
        35                  40                  45  


<210>  2976
<211>  81
<212>  PRT
<213>  homo sapiens

<400>  2976

Met Asn Arg Glu Gly Ala Pro Gly Lys Ser Pro Glu Glu Met Tyr Ile 
1               5                   10                  15      


Gln Gln Lys Val Arg Val Leu Leu Met Leu Arg Lys Met Gly Ser Asn 
            20                  25                  30          


Leu Thr Ala Ser Glu Glu Glu Phe Leu Arg Thr Tyr Ala Gly Val Val 
        35                  40                  45              


Asn Ser Gln Leu Ser Gln Leu Pro Pro His Ser Ile Asp Gln Gly Ala 
    50                  55                  60                  


Glu Asp Val Val Met Ala Phe Ser Arg Ser Glu Thr Glu Asp Arg Arg 
65                  70                  75                  80  


Gln 
    


<210>  2977
<211>  841
<212>  PRT
<213>  homo sapiens

<400>  2977

Met Lys Gly His Gly Glu Leu Gln Gly His Glu Arg Arg Met Ser Ser 
1               5                   10                  15      


Lys Gln Ala Thr Ser Pro Phe Ala Cys Ala Ala Asp Gly Glu Asp Ala 
            20                  25                  30          


Met Thr Gln Asp Leu Thr Ser Arg Glu Lys Glu Glu Gly Ser Asp Gln 
        35                  40                  45              


His Val Ala Ser His Leu Pro Leu His Pro Ile Met His Asn Lys Pro 
    50                  55                  60                  


His Ser Glu Glu Leu Pro Thr Leu Val Ser Thr Ile Gln Gln Asp Ala 
65                  70                  75                  80  


Asp Trp Asp Ser Val Leu Ser Ser Gln Gln Arg Met Glu Ser Glu Asn 
                85                  90                  95      


Asn Lys Leu Cys Ser Leu Tyr Ser Phe Arg Asn Thr Ser Thr Ser Pro 
            100                 105                 110         


His Lys Pro Asp Glu Gly Ser Arg Asp Arg Glu Ile Met Thr Ser Val 
        115                 120                 125             


Thr Phe Gly Thr Pro Glu Arg Arg Lys Gly Ser Leu Ala Asp Val Val 
    130                 135                 140                 


Asp Thr Leu Lys Gln Lys Lys Leu Glu Glu Met Thr Arg Thr Glu Gln 
145                 150                 155                 160 


Glu Asp Ser Ser Cys Met Glu Lys Leu Leu Ser Lys Asp Trp Lys Glu 
                165                 170                 175     


Lys Met Glu Arg Leu Asn Thr Ser Glu Leu Leu Gly Glu Ile Lys Gly 
            180                 185                 190         


Thr Pro Glu Ser Leu Ala Glu Lys Glu Arg Gln Leu Ser Thr Met Ile 
        195                 200                 205             


Thr Gln Leu Ile Ser Leu Arg Glu Gln Leu Leu Ala Ala His Asp Glu 
    210                 215                 220                 


Gln Lys Lys Leu Ala Ala Ser Gln Ile Glu Lys Gln Arg Gln Gln Met 
225                 230                 235                 240 


Asp Leu Ala Arg Gln Gln Gln Glu Gln Ile Ala Arg Gln Gln Gln Gln 
                245                 250                 255     


Leu Leu Gln Gln Gln His Lys Ile Asn Leu Leu Gln Gln Gln Ile Gln 
            260                 265                 270         


Val Gln Gly His Met Pro Pro Leu Met Ile Pro Ile Phe Pro His Asp 
        275                 280                 285             


Gln Arg Thr Leu Ala Ala Ala Ala Ala Ala Gln Gln Gly Phe Leu Phe 
    290                 295                 300                 


Pro Pro Gly Ile Thr Tyr Lys Pro Gly Asp Asn Tyr Pro Val Gln Phe 
305                 310                 315                 320 


Ile Pro Ser Thr Met Ala Ala Ala Ala Ala Ser Gly Leu Ser Pro Leu 
                325                 330                 335     


Gln Leu Gln Lys Gly His Val Ser His Pro Gln Ile Asn Gln Arg Leu 
            340                 345                 350         


Lys Gly Leu Ser Asp Arg Phe Gly Arg Asn Leu Asp Thr Phe Glu His 
        355                 360                 365             


Gly Gly Gly His Ser Tyr Asn His Lys Gln Ile Glu Gln Leu Tyr Ala 
    370                 375                 380                 


Ala Gln Leu Ala Ser Met Gln Val Ser Pro Gly Ala Lys Met Pro Ser 
385                 390                 395                 400 


Thr Pro Gln Pro Pro Asn Thr Ala Gly Thr Val Ser Pro Thr Gly Ile 
                405                 410                 415     


Lys Asn Glu Lys Arg Gly Thr Ser Pro Val Thr Gln Val Lys Asp Glu 
            420                 425                 430         


Ala Ala Ala Gln Pro Leu Asn Leu Ser Ser Arg Pro Lys Thr Ala Glu 
        435                 440                 445             


Pro Val Lys Ser Pro Thr Ser Pro Thr Gln Asn Leu Phe Pro Ala Ser 
    450                 455                 460                 


Lys Thr Ser Pro Val Asn Leu Pro Asn Lys Ser Ser Ile Pro Ser Pro 
465                 470                 475                 480 


Ile Gly Gly Ser Leu Gly Arg Gly Ser Ser Leu Asp Ile Leu Ser Ser 
                485                 490                 495     


Leu Asn Ser Pro Ala Leu Phe Gly Asp Gln Asp Thr Val Met Lys Ala 
            500                 505                 510         


Ile Gln Glu Ala Arg Lys Met Arg Glu Gln Ile Gln Arg Glu Gln Gln 
        515                 520                 525             


Gln Gln Gln Pro His Gly Val Asp Gly Lys Leu Ser Ser Ile Asn Asn 
    530                 535                 540                 


Met Gly Leu Asn Ser Cys Arg Asn Glu Lys Glu Arg Thr Arg Phe Glu 
545                 550                 555                 560 


Asn Leu Gly Pro Gln Leu Thr Gly Lys Ser Asn Glu Asp Gly Lys Leu 
                565                 570                 575     


Gly Pro Gly Val Ile Asp Leu Thr Arg Pro Glu Asp Ala Glu Gly Ser 
            580                 585                 590         


Lys Ala Met Asn Gly Ser Ala Ala Lys Leu Gln Gln Tyr Tyr Cys Trp 
        595                 600                 605             


Pro Thr Gly Gly Ala Thr Val Ala Glu Ala Arg Val Tyr Arg Asp Ala 
    610                 615                 620                 


Arg Gly Arg Ala Ser Ser Glu Pro His Ile Lys Arg Pro Met Asn Ala 
625                 630                 635                 640 


Phe Met Val Trp Ala Lys Asp Glu Arg Arg Lys Ile Leu Gln Ala Phe 
                645                 650                 655     


Pro Asp Met His Asn Ser Asn Ile Ser Lys Ile Leu Gly Ser Arg Trp 
            660                 665                 670         


Lys Ser Met Ser Asn Gln Glu Lys Gln Pro Tyr Tyr Glu Glu Gln Ala 
        675                 680                 685             


Arg Leu Ser Lys Ile His Leu Glu Lys Tyr Pro Asn Tyr Lys Tyr Lys 
    690                 695                 700                 


Pro Arg Pro Lys Arg Thr Cys Ile Val Asp Gly Lys Lys Leu Arg Ile 
705                 710                 715                 720 


Gly Glu Tyr Lys Gln Leu Met Arg Ser Arg Arg Gln Glu Met Arg Gln 
                725                 730                 735     


Phe Phe Thr Val Gly Gln Gln Pro Gln Ile Pro Ile Thr Thr Gly Thr 
            740                 745                 750         


Gly Val Val Tyr Pro Gly Ala Ile Thr Met Ala Thr Thr Thr Pro Ser 
        755                 760                 765             


Pro Gln Met Thr Ser Asp Cys Ser Ser Thr Ser Ala Ser Pro Glu Pro 
    770                 775                 780                 


Ser Leu Pro Val Ile Gln Ser Thr Tyr Gly Met Lys Thr Asp Gly Gly 
785                 790                 795                 800 


Ser Leu Ala Gly Asn Glu Met Ile Asn Gly Glu Asp Glu Met Glu Met 
                805                 810                 815     


Tyr Asp Asp Tyr Glu Asp Asp Pro Lys Ser Asp Tyr Ser Ser Glu Asn 
            820                 825                 830         


Glu Ala Pro Glu Ala Val Ser Ala Asn 
        835                 840     


<210>  2978
<211>  234
<212>  PRT
<213>  homo sapiens

<400>  2978

Met Arg Ser Gly Glu Glu Leu Asp Gly Phe Glu Gly Glu Ala Ser Ser 
1               5                   10                  15      


Thr Ser Met Ile Ser Gly Ala Ser Ser Pro Tyr Gln Pro Thr Thr Glu 
            20                  25                  30          


Pro Val Ser Gln Arg Arg Gly Leu Ala Gly Leu Arg Cys Asp Pro Asp 
        35                  40                  45              


Tyr Leu Arg Gly Ala Leu Gly Arg Leu Lys Val Ala Gln Val Ile Leu 
    50                  55                  60                  


Ala Leu Ile Ala Phe Ile Cys Ile Glu Thr Ile Met Ala Cys Ser Pro 
65                  70                  75                  80  


Cys Glu Gly Leu Tyr Phe Phe Glu Phe Val Ser Cys Ser Ala Phe Val 
                85                  90                  95      


Val Thr Gly Val Leu Leu Ile Met Phe Ser Leu Asn Leu His Met Arg 
            100                 105                 110         


Ile Pro Gln Ile Asn Trp Asn Leu Thr Asp Leu Val Asn Thr Gly Leu 
        115                 120                 125             


Ser Ala Phe Leu Phe Phe Ile Ala Ser Ile Val Leu Ala Ala Leu Asn 
    130                 135                 140                 


His Arg Ala Gly Ala Glu Ile Ala Ala Val Ile Phe Gly Phe Leu Ala 
145                 150                 155                 160 


Thr Ala Ala Tyr Ala Val Asn Thr Phe Leu Ala Val Gln Lys Trp Arg 
                165                 170                 175     


Val Ser Val Arg Gln Gln Ser Thr Asn Asp Tyr Ile Arg Ala Arg Thr 
            180                 185                 190         


Glu Ser Arg Asp Val Asp Ser Arg Pro Glu Ile Gln Arg Leu Asp Thr 
        195                 200                 205             


Phe Ser Tyr Ser Thr Asn Val Thr Val Arg Lys Lys Ser Pro Thr Asn 
    210                 215                 220                 


Leu Leu Ser Leu Asn His Trp Gln Leu Ala 
225                 230                 


<210>  2979
<211>  537
<212>  PRT
<213>  homo sapiens

<400>  2979

Met Glu Arg Val Asn Asp Ala Ser Cys Gly Pro Ser Gly Cys Tyr Thr 
1               5                   10                  15      


Tyr Gln Val Ser Arg His Ser Thr Glu Met Leu His Asn Leu Asn Gln 
            20                  25                  30          


Gln Arg Lys Asn Gly Gly Arg Phe Cys Asp Val Leu Leu Arg Val Gly 
        35                  40                  45              


Asp Glu Ser Phe Pro Ala His Arg Ala Val Leu Ala Ala Cys Ser Glu 
    50                  55                  60                  


Tyr Phe Glu Ser Val Phe Ser Ala Gln Leu Gly Asp Gly Gly Ala Ala 
65                  70                  75                  80  


Asp Gly Gly Pro Ala Asp Val Gly Gly Ala Thr Ala Ala Pro Gly Gly 
                85                  90                  95      


Gly Ala Gly Gly Ser Arg Glu Leu Glu Met His Thr Ile Ser Ser Lys 
            100                 105                 110         


Val Phe Gly Asp Ile Leu Asp Phe Ala Tyr Thr Ser Arg Ile Val Val 
        115                 120                 125             


Arg Leu Glu Ser Phe Pro Glu Leu Met Thr Ala Ala Lys Phe Leu Leu 
    130                 135                 140                 


Met Arg Ser Val Ile Glu Ile Cys Gln Glu Val Ile Lys Gln Ser Asn 
145                 150                 155                 160 


Val Gln Ile Leu Val Pro Pro Ala Arg Ala Asp Ile Met Leu Phe Arg 
                165                 170                 175     


Pro Pro Gly Thr Ser Asp Leu Gly Phe Pro Leu Asp Met Thr Asn Gly 
            180                 185                 190         


Ala Ala Leu Ala Ala Asn Ser Asn Gly Ile Ala Gly Ser Met Gln Pro 
        195                 200                 205             


Glu Glu Glu Ala Ala Arg Ala Ala Gly Ala Ala Ile Ala Gly Gln Ala 
    210                 215                 220                 


Ser Leu Pro Val Leu Pro Gly Val Asp Arg Leu Pro Met Val Ala Gly 
225                 230                 235                 240 


Pro Leu Ser Pro Gln Leu Leu Thr Ser Pro Phe Pro Ser Val Ala Ser 
                245                 250                 255     


Ser Ala Pro Pro Leu Thr Gly Lys Arg Gly Arg Gly Arg Pro Arg Lys 
            260                 265                 270         


Ala Asn Leu Leu Asp Ser Met Phe Gly Ser Pro Gly Gly Leu Arg Glu 
        275                 280                 285             


Ala Gly Ile Leu Pro Cys Gly Leu Cys Gly Lys Val Phe Thr Asp Ala 
    290                 295                 300                 


Asn Arg Leu Arg Gln His Glu Ala Gln His Gly Val Thr Ser Leu Gln 
305                 310                 315                 320 


Leu Gly Tyr Ile Asp Leu Pro Pro Pro Arg Leu Gly Glu Asn Gly Leu 
                325                 330                 335     


Pro Ile Ser Glu Asp Pro Asp Gly Pro Arg Lys Arg Ser Arg Thr Arg 
            340                 345                 350         


Lys Gln Val Ala Cys Glu Ile Cys Gly Lys Ile Phe Arg Asp Val Tyr 
        355                 360                 365             


His Leu Asn Arg His Lys Leu Ser His Ser Gly Glu Lys Pro Tyr Ser 
    370                 375                 380                 


Cys Pro Val Cys Gly Leu Arg Phe Lys Arg Lys Asp Arg Met Ser Tyr 
385                 390                 395                 400 


His Val Arg Ser His Asp Gly Ser Val Gly Lys Pro Tyr Ile Cys Gln 
                405                 410                 415     


Ser Cys Gly Lys Gly Phe Ser Arg Pro Asp His Leu Asn Gly His Ile 
            420                 425                 430         


Lys Gln Val His Thr Ser Glu Arg Pro His Lys Cys Gln Val Trp Val 
        435                 440                 445             


Gly Ser Ser Ser Gly Leu Pro Pro Leu Glu Pro Leu Pro Ser Asp Leu 
    450                 455                 460                 


Pro Ser Trp Asp Phe Ala Gln Pro Ala Leu Trp Arg Ser Ser His Ser 
465                 470                 475                 480 


Val Pro Asp Thr Ala Phe Ser Leu Ser Leu Lys Lys Ser Phe Pro Ala 
                485                 490                 495     


Leu Glu Asn Leu Gly Pro Ala His Ser Ser Asn Thr Leu Phe Cys Pro 
            500                 505                 510         


Ala Pro Pro Gly Tyr Leu Arg Gln Gly Trp Thr Thr Pro Glu Gly Ser 
        515                 520                 525             


Arg Ala Phe Thr Gln Trp Pro Val Gly 
    530                 535         


<210>  2980
<211>  349
<212>  PRT
<213>  homo sapiens

<400>  2980

Met Gly Asp Met Gly Asp Pro Pro Lys Lys Lys Arg Leu Ile Ser Leu 
1               5                   10                  15      


Cys Val Gly Cys Gly Asn Gln Ile His Asp Gln Tyr Ile Leu Arg Val 
            20                  25                  30          


Ser Pro Asp Leu Glu Trp His Ala Ala Cys Leu Lys Cys Ala Glu Cys 
        35                  40                  45              


Asn Gln Tyr Leu Asp Glu Ser Cys Thr Cys Phe Val Arg Asp Gly Lys 
    50                  55                  60                  


Thr Tyr Cys Lys Arg Asp Tyr Ile Arg Leu Tyr Gly Ile Lys Cys Ala 
65                  70                  75                  80  


Lys Cys Ser Ile Gly Phe Ser Lys Asn Asp Phe Val Met Arg Ala Arg 
                85                  90                  95      


Ser Lys Val Tyr His Ile Glu Cys Phe Arg Cys Val Ala Cys Ser Arg 
            100                 105                 110         


Gln Leu Ile Pro Gly Asp Glu Phe Ala Leu Arg Glu Asp Gly Leu Phe 
        115                 120                 125             


Cys Arg Ala Asp His Asp Val Val Glu Arg Ala Ser Leu Gly Ala Gly 
    130                 135                 140                 


Asp Pro Leu Ser Pro Leu His Pro Ala Arg Pro Leu Gln Met Ala Ala 
145                 150                 155                 160 


Glu Pro Ile Ser Ala Arg Gln Pro Ala Leu Arg Pro His Val His Lys 
                165                 170                 175     


Gln Pro Glu Lys Thr Thr Arg Val Arg Thr Val Leu Asn Glu Lys Gln 
            180                 185                 190         


Leu His Thr Leu Arg Thr Cys Tyr Ala Ala Asn Pro Arg Pro Asp Ala 
        195                 200                 205             


Leu Met Lys Glu Gln Leu Val Glu Met Thr Gly Leu Ser Pro Arg Val 
    210                 215                 220                 


Ile Arg Val Trp Phe Gln Asn Lys Arg Cys Lys Asp Lys Lys Arg Ser 
225                 230                 235                 240 


Ile Met Met Lys Gln Leu Gln Gln Gln Gln Pro Asn Asp Lys Thr Asn 
                245                 250                 255     


Ile Gln Gly Met Thr Gly Thr Pro Met Val Ala Ala Ser Pro Glu Arg 
            260                 265                 270         


His Asp Gly Gly Leu Gln Ala Asn Pro Val Glu Val Gln Ser Tyr Gln 
        275                 280                 285             


Pro Pro Trp Lys Val Leu Ser Asp Phe Ala Leu Gln Ser Asp Ile Asp 
    290                 295                 300                 


Gln Pro Ala Phe Gln Gln Leu Val Asn Phe Ser Glu Gly Gly Pro Gly 
305                 310                 315                 320 


Ser Asn Ser Thr Gly Ser Glu Val Ala Ser Met Ser Ser Gln Leu Pro 
                325                 330                 335     


Asp Thr Pro Asn Ser Met Val Ala Ser Pro Ile Glu Ala 
            340                 345                 


<210>  2981
<211>  323
<212>  PRT
<213>  homo sapiens

<400>  2981

Met Ala Ala Ala Arg Pro Glu Ala Gln Ser Arg Ser Ser Pro Thr Pro 
1               5                   10                  15      


Glu Ser Arg Ser Gln Glu Pro Leu Asp Leu Val Leu Val Pro Asp Asp 
            20                  25                  30          


Cys Arg Pro Gly Thr Pro Pro Ser Asp Leu Ile Glu Ile Gln Val Val 
        35                  40                  45              


Lys Val Thr Asp Thr Thr Leu Val Pro Glu Pro Pro Glu Pro Gly Ser 
    50                  55                  60                  


Phe His Cys Ala Leu Cys Pro Ala Ala Phe Arg Leu Val Ser Glu Leu 
65                  70                  75                  80  


Leu Phe His Glu His Gly His Leu Ala Gly Ala Glu Gly Gly Gly Gln 
                85                  90                  95      


Gly Gly Asp Pro Ser Arg Cys His Val Cys Gly His Ser Cys Pro Gly 
            100                 105                 110         


Pro Ala Ser Leu Arg Ala His Tyr Ser Leu His Thr Gly Glu Arg Pro 
        115                 120                 125             


Tyr Arg Cys Ala Leu Cys Pro Arg Ala Phe Lys Ala Leu Ala Pro Leu 
    130                 135                 140                 


Leu Arg His Gln His Arg His Gly Val Glu Pro Gly Thr Ser Arg Arg 
145                 150                 155                 160 


Pro Pro Asp Thr Ala Ala Val Ala Glu Gln Arg Pro Gly Val Ala Pro 
                165                 170                 175     


Glu Arg Ala Glu Val Val Met Ala Ala Ala Ala Ala Gly Ala Ala Val 
            180                 185                 190         


Gly Lys Pro Phe Ala Cys Arg Phe Cys Ala Lys Pro Phe Arg Arg Ser 
        195                 200                 205             


Ser Asp Met Arg Asp His Glu Arg Val His Thr Gly Glu Arg Pro Tyr 
    210                 215                 220                 


His Cys Gly Ile Cys Gly Lys Gly Phe Thr Gln Ser Ser Val Leu Ser 
225                 230                 235                 240 


Gly His Ala Arg Ile His Thr Gly Glu Arg Pro Phe Arg Cys Thr Leu 
                245                 250                 255     


Cys Asp Arg Thr Phe Asn Asn Ser Ser Asn Phe Arg Lys His Gln Arg 
            260                 265                 270         


Thr His Phe His Gly Pro Gly Pro Gly Leu Gly Asp Ser Gly Gly Gln 
        275                 280                 285             


Leu Gly Ser Ser Ala Ala Glu Gly Ser Gly Ser Gly Cys Gly Val Gly 
    290                 295                 300                 


Asp Pro Ala Glu Glu Gly Arg Gly Glu Thr Ala Lys Val Lys Val Glu 
305                 310                 315                 320 


Ala Asp Gln 
            


<210>  2982
<211>  595
<212>  PRT
<213>  homo sapiens

<400>  2982

Met Gly Pro Leu Thr Phe Arg Asp Val Ala Ile Glu Phe Ser Leu Lys 
1               5                   10                  15      


Glu Trp Gln Cys Leu Asp Thr Ala Gln Arg Asn Leu Tyr Arg Asn Val 
            20                  25                  30          


Met Leu Glu Asn Tyr Arg Asn Leu Val Phe Leu Gly Ile Thr Val Ser 
        35                  40                  45              


Lys Pro Asp Leu Ile Thr Cys Leu Glu Gln Gly Lys Glu Ala Trp Ser 
    50                  55                  60                  


Met Lys Arg His Glu Ile Met Val Ala Lys Pro Thr Val Met Cys Ser 
65                  70                  75                  80  


His Phe Ala Gln Asp Leu Trp Pro Glu Gln Asn Ile Lys Asp Ser Phe 
                85                  90                  95      


Gln Lys Val Thr Leu Lys Arg Tyr Gly Lys Cys Arg His Glu Asn Leu 
            100                 105                 110         


Pro Leu Arg Lys Gly Cys Glu Ser Met Asp Glu Cys Lys Met His Lys 
        115                 120                 125             


Gly Gly Cys Asn Gly Leu Asn Gln Cys Leu Thr Ala Thr Gln Ser Lys 
    130                 135                 140                 


Ile Phe Gln Cys Asp Lys Tyr Val Lys Val Ala His Lys Phe Ser Asn 
145                 150                 155                 160 


Ser Asn Arg His Glu Ile Arg His Thr Lys Lys Lys Pro Phe Lys Cys 
                165                 170                 175     


Thr Lys Cys Gly Lys Ser Phe Gly Met Ile Ser Cys Leu Thr Glu His 
            180                 185                 190         


Ser Arg Ile His Thr Arg Val Asn Phe Tyr Lys Cys Glu Glu Cys Gly 
        195                 200                 205             


Lys Ala Phe Asn Trp Ser Ser Thr Leu Thr Lys His Lys Arg Ile His 
    210                 215                 220                 


Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn 
225                 230                 235                 240 


Gln Ser Ser Asn Leu Ile Lys His Lys Lys Ile His Thr Gly Glu Lys 
                245                 250                 255     


Pro Tyr Lys Cys Glu Glu Cys Gly Lys Thr Phe Asn Arg Phe Ser Thr 
            260                 265                 270         


Leu Thr Thr His Lys Ile Ile His Thr Gly Glu Lys Pro Tyr Lys Cys 
        275                 280                 285             


Lys Glu Cys Gly Lys Ala Phe Asn Arg Ser Ser Thr Leu Thr Thr His 
    290                 295                 300                 


Arg Lys Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu Cys Gly 
305                 310                 315                 320 


Lys Ala Phe Lys Gln Ser Ser Asn Leu Thr Thr His Lys Ile Ile His 
                325                 330                 335     


Thr Gly Glu Lys Pro Tyr Lys Cys Lys Lys Cys Gly Lys Ala Phe Asn 
            340                 345                 350         


Gln Ser Ala His Leu Thr Thr His Glu Val Ile His Thr Gly Glu Lys 
        355                 360                 365             


Pro Tyr Lys Cys Glu Lys Cys Gly Lys Ala Phe Asn His Phe Ser His 
    370                 375                 380                 


Leu Thr Thr His Lys Ile Ile His Thr Gly Glu Lys Pro Tyr Lys Cys 
385                 390                 395                 400 


Lys Glu Cys Gly Lys Ala Phe Lys His Ser Ser Thr Leu Thr Lys His 
                405                 410                 415     


Lys Ile Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Lys Glu Cys Glu 
            420                 425                 430         


Lys Ala Phe Asn Gln Ser Ser Lys Leu Thr Glu His Lys Lys Ile His 
        435                 440                 445             


Thr Gly Glu Lys Pro Tyr Glu Cys Glu Lys Cys Gly Lys Ala Phe Asn 
    450                 455                 460                 


Gln Ser Ser Asn Leu Thr Arg His Lys Lys Ser His Thr Glu Glu Lys 
465                 470                 475                 480 


Pro Tyr Lys Cys Glu Glu Cys Gly Lys Gly Phe Lys Trp Pro Ser Thr 
                485                 490                 495     


Leu Thr Ile His Lys Ile Ile His Thr Gly Glu Lys Pro Tyr Lys Cys 
            500                 505                 510         


Glu Glu Cys Gly Lys Ala Phe Asn Gln Ser Ser Lys Leu Thr Lys His 
        515                 520                 525             


Lys Lys Ile His Thr Gly Glu Lys Pro Tyr Thr Cys Glu Glu Cys Gly 
    530                 535                 540                 


Lys Ala Phe Asn Gln Ser Ser Asn Leu Thr Lys His Lys Arg Ile His 
545                 550                 555                 560 


Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu Cys Asp Lys Ala Phe Lys 
                565                 570                 575     


Trp Ser Ser Val Leu Thr Lys His Lys Ile Ile His Thr Gly Glu Lys 
            580                 585                 590         


Leu Gln Ile 
        595 


<210>  2983
<211>  348
<212>  PRT
<213>  homo sapiens

<400>  2983

Met Thr Thr Ala Leu Glu Pro Glu Asp Gln Lys Gly Leu Leu Ile Ile 
1               5                   10                  15      


Lys Ala Glu Asp His Tyr Trp Gly Gln Asp Ser Ser Ser Gln Lys Cys 
            20                  25                  30          


Ser Pro His Arg Arg Glu Leu Tyr Arg Gln His Phe Arg Lys Leu Cys 
        35                  40                  45              


Tyr Gln Asp Ala Pro Gly Pro Arg Glu Ala Leu Thr Gln Leu Trp Glu 
    50                  55                  60                  


Leu Cys Arg Gln Trp Leu Arg Pro Glu Cys His Thr Lys Glu Gln Ile 
65                  70                  75                  80  


Leu Asp Leu Leu Val Leu Glu Gln Phe Leu Ser Ile Leu Pro Lys Asp 
                85                  90                  95      


Leu Gln Ala Trp Val Arg Ala His His Pro Glu Thr Gly Glu Glu Ala 
            100                 105                 110         


Val Thr Val Leu Glu Asp Leu Glu Arg Glu Leu Asp Glu Pro Gly Lys 
        115                 120                 125             


Gln Val Pro Gly Asn Ser Glu Arg Arg Asp Ile Leu Met Asp Lys Leu 
    130                 135                 140                 


Ala Pro Leu Gly Arg Pro Tyr Glu Ser Leu Thr Val Gln Leu His Pro 
145                 150                 155                 160 


Lys Lys Thr Gln Leu Glu Gln Glu Ala Gly Lys Pro Gln Arg Asn Gly 
                165                 170                 175     


Asp Lys Thr Arg Thr Lys Asn Glu Glu Leu Phe Gln Lys Glu Asp Met 
            180                 185                 190         


Pro Lys Asp Lys Glu Phe Leu Gly Glu Ile Asn Asp Arg Leu Asn Lys 
        195                 200                 205             


Asp Thr Pro Gln His Pro Lys Ser Lys Asp Ile Ile Glu Asn Glu Gly 
    210                 215                 220                 


Arg Ser Glu Trp Gln Gln Arg Glu Arg Arg Arg Tyr Lys Cys Asp Glu 
225                 230                 235                 240 


Cys Gly Lys Ser Phe Ser His Ser Ser Asp Leu Ser Lys His Arg Arg 
                245                 250                 255     


Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Asp Glu Cys Gly Lys Ala 
            260                 265                 270         


Phe Ile Gln Arg Ser His Leu Ile Gly His His Arg Val His Thr Gly 
        275                 280                 285             


Val Lys Pro Tyr Lys Cys Lys Glu Cys Gly Lys Asp Phe Ser Gly Arg 
    290                 295                 300                 


Thr Gly Leu Ile Gln His Gln Arg Ile His Thr Gly Glu Lys Pro Tyr 
305                 310                 315                 320 


Glu Cys Asp Glu Cys Gly Arg Pro Phe Arg Val Ser Ser Ala Leu Ile 
                325                 330                 335     


Arg His Gln Arg Ile His Thr Ala Asn Lys Leu Tyr 
            340                 345             


<210>  2984
<211>  1516
<212>  PRT
<213>  homo sapiens

<400>  2984

Met Ala Pro Tyr Pro Cys Gly Cys His Ile Leu Leu Leu Leu Phe Cys 
1               5                   10                  15      


Cys Leu Ala Ala Ala Arg Ala Asn Leu Leu Asn Leu Asn Trp Leu Trp 
            20                  25                  30          


Phe Asn Asn Glu Asp Thr Ser His Ala Ala Thr Thr Ile Pro Glu Pro 
        35                  40                  45              


Gln Gly Pro Leu Pro Val Gln Pro Thr Ala Asp Thr Thr Thr His Val 
    50                  55                  60                  


Thr Pro Arg Asn Gly Ser Thr Glu Pro Ala Thr Ala Pro Gly Ser Pro 
65                  70                  75                  80  


Glu Pro Pro Ser Glu Leu Leu Glu Asp Gly Gln Asp Thr Pro Thr Ser 
                85                  90                  95      


Ala Glu Ser Pro Asp Ala Pro Glu Glu Asn Ile Ala Gly Val Gly Ala 
            100                 105                 110         


Glu Ile Leu Asn Val Ala Lys Gly Ile Arg Ser Phe Val Gln Leu Trp 
        115                 120                 125             


Asn Asp Thr Val Pro Thr Glu Ser Leu Ala Arg Ala Glu Thr Leu Val 
    130                 135                 140                 


Leu Glu Thr Pro Val Gly Pro Leu Ala Leu Ala Gly Pro Ser Ser Thr 
145                 150                 155                 160 


Pro Gln Glu Asn Gly Thr Thr Leu Trp Pro Ser Arg Gly Ile Pro Ser 
                165                 170                 175     


Ser Pro Gly Ala His Thr Thr Glu Ala Gly Thr Leu Pro Ala Pro Thr 
            180                 185                 190         


Pro Ser Pro Pro Ser Leu Gly Arg Pro Trp Ala Pro Leu Thr Gly Pro 
        195                 200                 205             


Ser Val Pro Pro Pro Ser Ser Glu Arg Ile Ser Glu Glu Val Gly Leu 
    210                 215                 220                 


Leu Gln Leu Leu Gly Asp Pro Pro Pro Gln Gln Val Thr Gln Thr Asp 
225                 230                 235                 240 


Asp Pro Asp Val Gly Leu Ala Tyr Val Phe Gly Pro Asp Ala Asn Ser 
                245                 250                 255     


Gly Gln Val Ala Arg Tyr His Phe Pro Ser Leu Phe Phe Arg Asp Phe 
            260                 265                 270         


Ser Leu Leu Phe His Ile Arg Pro Ala Thr Glu Gly Pro Gly Val Leu 
        275                 280                 285             


Phe Ala Ile Thr Asp Ser Ala Gln Ala Met Val Leu Leu Gly Val Lys 
    290                 295                 300                 


Leu Ser Gly Val Gln Asp Gly His Gln Asp Ile Ser Leu Leu Tyr Thr 
305                 310                 315                 320 


Glu Pro Gly Ala Gly Gln Thr His Thr Ala Ala Ser Phe Arg Leu Pro 
                325                 330                 335     


Ala Phe Val Gly Gln Trp Thr His Leu Ala Leu Ser Val Ala Gly Gly 
            340                 345                 350         


Phe Val Ala Leu Tyr Val Asp Cys Glu Glu Phe Gln Arg Met Pro Leu 
        355                 360                 365             


Ala Arg Ser Ser Arg Gly Leu Glu Leu Glu Pro Gly Ala Gly Leu Phe 
    370                 375                 380                 


Val Ala Gln Ala Gly Gly Ala Asp Pro Asp Lys Phe Gln Gly Val Ile 
385                 390                 395                 400 


Ala Glu Leu Lys Val Arg Arg Asp Pro Gln Val Ser Pro Met His Cys 
                405                 410                 415     


Leu Asp Glu Glu Gly Asp Asp Ser Asp Gly Ala Ser Gly Asp Ser Gly 
            420                 425                 430         


Ser Gly Leu Gly Asp Ala Arg Glu Leu Leu Arg Glu Glu Thr Gly Ala 
        435                 440                 445             


Ala Leu Lys Pro Arg Leu Pro Ala Pro Pro Pro Val Thr Thr Pro Pro 
    450                 455                 460                 


Leu Ala Gly Gly Ser Ser Thr Glu Asp Ser Arg Ser Glu Glu Val Glu 
465                 470                 475                 480 


Glu Gln Thr Thr Val Ala Ser Leu Gly Ala Gln Thr Leu Pro Gly Ser 
                485                 490                 495     


Asp Ser Val Ser Thr Trp Asp Gly Ser Val Arg Thr Pro Gly Gly Arg 
            500                 505                 510         


Val Lys Glu Gly Gly Leu Lys Gly Gln Lys Gly Glu Pro Gly Val Pro 
        515                 520                 525             


Gly Pro Pro Gly Arg Ala Gly Pro Pro Gly Ser Pro Cys Leu Pro Gly 
    530                 535                 540                 


Pro Pro Gly Leu Pro Cys Pro Val Ser Pro Leu Gly Pro Ala Gly Pro 
545                 550                 555                 560 


Ala Leu Gln Thr Val Pro Gly Pro Gln Gly Pro Pro Gly Pro Pro Gly 
                565                 570                 575     


Arg Asp Gly Thr Pro Gly Arg Asp Gly Glu Pro Gly Asp Pro Gly Glu 
            580                 585                 590         


Asp Gly Lys Pro Gly Asp Thr Gly Pro Gln Gly Phe Pro Gly Thr Pro 
        595                 600                 605             


Gly Asp Val Gly Pro Lys Gly Asp Lys Gly Asp Pro Gly Val Gly Glu 
    610                 615                 620                 


Arg Gly Pro Pro Gly Pro Gln Gly Pro Pro Gly Pro Pro Gly Pro Ser 
625                 630                 635                 640 


Phe Arg His Asp Lys Leu Thr Phe Ile Asp Met Glu Gly Ser Gly Phe 
                645                 650                 655     


Gly Gly Asp Leu Glu Ala Leu Arg Gly Pro Arg Gly Phe Pro Gly Pro 
            660                 665                 670         


Pro Gly Pro Pro Gly Val Pro Gly Leu Pro Gly Glu Pro Gly Arg Phe 
        675                 680                 685             


Gly Val Asn Ser Ser Asp Val Pro Gly Pro Ala Gly Leu Pro Gly Val 
    690                 695                 700                 


Pro Gly Arg Glu Gly Pro Pro Gly Phe Pro Gly Leu Pro Gly Pro Pro 
705                 710                 715                 720 


Gly Pro Pro Gly Arg Glu Gly Pro Pro Gly Arg Thr Gly Gln Lys Gly 
                725                 730                 735     


Ser Leu Gly Glu Ala Gly Ala Pro Gly His Lys Gly Ser Lys Gly Ala 
            740                 745                 750         


Pro Gly Pro Ala Gly Ala Arg Gly Glu Ser Gly Leu Ala Gly Ala Pro 
        755                 760                 765             


Gly Pro Ala Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly 
    770                 775                 780                 


Pro Gly Leu Pro Ala Gly Phe Asp Asp Met Glu Gly Ser Gly Gly Pro 
785                 790                 795                 800 


Phe Trp Ser Thr Ala Arg Ser Ala Asp Gly Pro Gln Gly Pro Pro Gly 
                805                 810                 815     


Leu Pro Gly Leu Lys Gly Asp Pro Gly Val Pro Gly Leu Pro Gly Ala 
            820                 825                 830         


Lys Gly Glu Val Gly Ala Asp Gly Val Pro Gly Phe Pro Gly Leu Pro 
        835                 840                 845             


Gly Arg Glu Gly Ile Ala Gly Pro Gln Gly Pro Lys Gly Asp Arg Gly 
    850                 855                 860                 


Ser Arg Gly Glu Lys Gly Asp Pro Gly Lys Asp Gly Val Gly Gln Pro 
865                 870                 875                 880 


Gly Leu Pro Gly Pro Pro Gly Pro Pro Gly Pro Val Val Tyr Val Ser 
                885                 890                 895     


Glu Gln Asp Gly Ser Val Leu Ser Val Pro Gly Pro Glu Gly Arg Pro 
            900                 905                 910         


Gly Phe Ala Gly Phe Pro Gly Pro Ala Gly Pro Lys Gly Asn Leu Gly 
        915                 920                 925             


Ser Lys Gly Glu Arg Gly Ser Pro Gly Pro Lys Gly Glu Lys Gly Glu 
    930                 935                 940                 


Pro Gly Ser Ile Phe Ser Pro Asp Gly Gly Ala Leu Gly Pro Ala Gln 
945                 950                 955                 960 


Lys Gly Ala Lys Gly Glu Pro Gly Phe Arg Gly Pro Pro Gly Pro Tyr 
                965                 970                 975     


Gly Arg Pro Gly Tyr Lys Gly Glu Ile Gly Phe Pro Gly Arg Pro Gly 
            980                 985                 990         


Arg Pro Gly Met Asn Gly Leu Lys  Gly Glu Lys Gly Glu  Pro Gly Asp 
        995                 1000                 1005             


Ala Ser  Leu Gly Phe Gly Met  Arg Gly Met Pro Gly  Pro Pro Gly 
    1010                 1015                 1020             


Pro Pro  Gly Pro Pro Gly Pro  Pro Gly Thr Pro Val  Tyr Asp Ser 
    1025                 1030                 1035             


Asn Val  Phe Ala Glu Ser Ser  Arg Pro Gly Pro Pro  Gly Leu Pro 
    1040                 1045                 1050             


Gly Asn  Gln Gly Pro Pro Gly  Pro Lys Gly Ala Lys  Gly Glu Val 
    1055                 1060                 1065             


Gly Pro  Pro Gly Pro Pro Gly  Gln Phe Pro Phe Asp  Phe Leu Gln 
    1070                 1075                 1080             


Leu Glu  Ala Glu Met Lys Gly  Glu Lys Gly Asp Arg  Gly Asp Ala 
    1085                 1090                 1095             


Gly Gln  Lys Gly Glu Arg Gly  Glu Pro Gly Gly Gly  Gly Phe Phe 
    1100                 1105                 1110             


Gly Ser  Ser Leu Pro Gly Pro  Pro Gly Pro Pro Gly  Pro Arg Gly 
    1115                 1120                 1125             


Tyr Pro  Gly Ile Pro Gly Pro  Lys Gly Glu Ser Ile  Arg Gly Gln 
    1130                 1135                 1140             


Pro Gly  Pro Pro Gly Pro Gln  Gly Pro Pro Gly Ile  Gly Tyr Glu 
    1145                 1150                 1155             


Gly Arg  Gln Gly Pro Pro Gly  Pro Pro Gly Pro Pro  Gly Pro Pro 
    1160                 1165                 1170             


Ser Phe  Pro Gly Pro His Arg  Gln Thr Ile Ser Val  Pro Gly Pro 
    1175                 1180                 1185             


Pro Gly  Pro Pro Gly Pro Pro  Gly Pro Pro Gly Thr  Met Gly Ala 
    1190                 1195                 1200             


Ser Ser  Gly Val Arg Leu Trp  Ala Thr Arg Gln Ala  Met Leu Gly 
    1205                 1210                 1215             


Gln Val  His Glu Val Pro Glu  Gly Trp Leu Ile Phe  Val Ala Glu 
    1220                 1225                 1230             


Gln Glu  Glu Leu Tyr Val Arg  Val Gln Asn Gly Phe  Arg Lys Val 
    1235                 1240                 1245             


Gln Leu  Glu Ala Arg Thr Pro  Leu Pro Arg Gly Thr  Asp Asn Glu 
    1250                 1255                 1260             


Val Ala  Ala Leu Gln Pro Pro  Val Val Gln Leu His  Asp Ser Asn 
    1265                 1270                 1275             


Pro Tyr  Pro Arg Arg Glu His  Pro His Pro Thr Ala  Arg Pro Trp 
    1280                 1285                 1290             


Arg Ala  Asp Asp Ile Leu Ala  Ser Pro Pro Arg Leu  Pro Glu Pro 
    1295                 1300                 1305             


Gln Pro  Tyr Pro Gly Ala Pro  His His Ser Ser Tyr  Val His Leu 
    1310                 1315                 1320             


Arg Pro  Ala Arg Pro Thr Ser  Pro Pro Ala His Ser  His Arg Asp 
    1325                 1330                 1335             


Phe Gln  Pro Val Leu His Leu  Val Ala Leu Asn Ser  Pro Leu Ser 
    1340                 1345                 1350             


Gly Gly  Met Arg Gly Ile Arg  Gly Ala Asp Phe Gln  Cys Phe Gln 
    1355                 1360                 1365             


Gln Ala  Arg Ala Val Gly Leu  Ala Gly Thr Phe Arg  Ala Phe Leu 
    1370                 1375                 1380             


Ser Ser  Arg Leu Gln Asp Leu  Tyr Ser Ile Val Arg  Arg Ala Asp 
    1385                 1390                 1395             


Arg Ala  Ala Val Pro Ile Val  Asn Leu Lys Asp Glu  Leu Leu Phe 
    1400                 1405                 1410             


Pro Ser  Trp Glu Ala Leu Phe  Ser Gly Ser Glu Gly  Pro Leu Lys 
    1415                 1420                 1425             


Pro Gly  Ala Arg Ile Phe Ser  Phe Asp Gly Lys Asp  Val Leu Arg 
    1430                 1435                 1440             


His Pro  Thr Trp Pro Gln Lys  Ser Val Trp His Gly  Ser Asp Pro 
    1445                 1450                 1455             


Asn Gly  Arg Arg Leu Thr Glu  Ser Tyr Cys Glu Thr  Trp Arg Thr 
    1460                 1465                 1470             


Glu Ala  Pro Ser Ala Thr Gly  Gln Ala Ser Ser Leu  Leu Gly Gly 
    1475                 1480                 1485             


Arg Leu  Leu Gly Gln Ser Ala  Ala Ser Cys His His  Ala Tyr Ile 
    1490                 1495                 1500             


Val Leu  Cys Ile Glu Asn Ser  Phe Met Thr Ala Ser  Lys 
    1505                 1510                 1515     


<210>  2985
<211>  427
<212>  PRT
<213>  homo sapiens

<400>  2985

Met Ser Lys Leu Pro Arg Glu Leu Thr Arg Asp Leu Glu Arg Ser Leu 
1               5                   10                  15      


Pro Ala Val Ala Ser Leu Gly Ser Ser Leu Ser His Ser Gln Ser Leu 
            20                  25                  30          


Ser Ser His Leu Leu Pro Pro Pro Glu Lys Arg Arg Ala Ile Ser Asp 
        35                  40                  45              


Val Arg Arg Thr Phe Cys Leu Phe Val Thr Phe Asp Leu Leu Phe Ile 
    50                  55                  60                  


Ser Leu Leu Trp Ile Ile Glu Leu Asn Thr Asn Thr Gly Ile Arg Lys 
65                  70                  75                  80  


Asn Leu Glu Gln Glu Ile Ile Gln Tyr Asn Phe Lys Thr Ser Phe Phe 
                85                  90                  95      


Asp Ile Phe Val Leu Ala Phe Phe Arg Phe Ser Gly Leu Leu Leu Gly 
            100                 105                 110         


Tyr Ala Val Leu Arg Leu Arg His Trp Trp Val Ile Ala Leu Leu Ser 
        115                 120                 125             


Lys Gly Ala Phe Gly Tyr Leu Leu Pro Ile Val Ser Phe Val Leu Ala 
    130                 135                 140                 


Trp Leu Glu Thr Trp Phe Leu Asp Phe Lys Val Leu Pro Gln Glu Ala 
145                 150                 155                 160 


Glu Glu Glu Arg Trp Tyr Leu Ala Ala Gln Val Ala Val Ala Arg Gly 
                165                 170                 175     


Pro Leu Leu Phe Ser Gly Ala Leu Ser Glu Gly Gln Phe Tyr Ser Pro 
            180                 185                 190         


Pro Glu Ser Phe Ala Gly Ser Asp Asn Glu Ser Asp Glu Glu Val Ala 
        195                 200                 205             


Gly Lys Lys Ser Phe Ser Ala Gln Glu Arg Glu Tyr Ile Arg Gln Gly 
    210                 215                 220                 


Lys Glu Ala Thr Ala Val Val Asp Gln Ile Leu Ala Gln Glu Glu Asn 
225                 230                 235                 240 


Trp Lys Phe Glu Lys Asn Asn Glu Tyr Gly Asp Thr Val Tyr Thr Ile 
                245                 250                 255     


Glu Val Pro Phe His Gly Lys Thr Phe Ile Leu Lys Thr Phe Leu Pro 
            260                 265                 270         


Cys Pro Ala Glu Leu Val Tyr Gln Glu Val Ile Leu Gln Pro Glu Arg 
        275                 280                 285             


Met Val Leu Trp Asn Lys Thr Val Thr Ala Cys Gln Ile Leu Gln Arg 
    290                 295                 300                 


Val Glu Asp Asn Thr Leu Ile Ser Tyr Asp Val Ser Ala Gly Ala Ala 
305                 310                 315                 320 


Gly Gly Val Val Ser Pro Arg Asp Phe Val Asn Val Arg Arg Ile Glu 
                325                 330                 335     


Arg Arg Arg Asp Arg Tyr Leu Ser Ser Gly Ile Ala Thr Ser His Ser 
            340                 345                 350         


Ala Lys Pro Pro Thr His Lys Tyr Val Arg Gly Glu Asn Gly Pro Gly 
        355                 360                 365             


Gly Phe Ile Val Leu Lys Ser Ala Ser Asn Pro Arg Val Cys Thr Phe 
    370                 375                 380                 


Val Trp Ile Leu Asn Thr Asp Leu Lys Gly Arg Leu Pro Arg Tyr Leu 
385                 390                 395                 400 


Ile His Gln Ser Leu Ala Ala Thr Met Phe Glu Phe Ala Phe His Leu 
                405                 410                 415     


Arg Gln Arg Ile Ser Glu Leu Gly Ala Arg Ala 
            420                 425         


<210>  2986
<211>  750
<212>  PRT
<213>  homo sapiens

<400>  2986

Met Ser Gln Trp Tyr Glu Leu Gln Gln Leu Asp Ser Lys Phe Leu Glu 
1               5                   10                  15      


Gln Val His Gln Leu Tyr Asp Asp Ser Phe Pro Met Glu Ile Arg Gln 
            20                  25                  30          


Tyr Leu Ala Gln Trp Leu Glu Lys Gln Asp Trp Glu His Ala Ala Asn 
        35                  40                  45              


Asp Val Ser Phe Ala Thr Ile Arg Phe His Asp Leu Leu Ser Gln Leu 
    50                  55                  60                  


Asp Asp Gln Tyr Ser Arg Phe Ser Leu Glu Asn Asn Phe Leu Leu Gln 
65                  70                  75                  80  


His Asn Ile Arg Lys Ser Lys Arg Asn Leu Gln Asp Asn Phe Gln Glu 
                85                  90                  95      


Asp Pro Ile Gln Met Ser Met Ile Ile Tyr Ser Cys Leu Lys Glu Glu 
            100                 105                 110         


Arg Lys Ile Leu Glu Asn Ala Gln Arg Phe Asn Gln Ala Gln Ser Gly 
        115                 120                 125             


Asn Ile Gln Ser Thr Val Met Leu Asp Lys Gln Lys Glu Leu Asp Ser 
    130                 135                 140                 


Lys Val Arg Asn Val Lys Asp Lys Val Met Cys Ile Glu His Glu Ile 
145                 150                 155                 160 


Lys Ser Leu Glu Asp Leu Gln Asp Glu Tyr Asp Phe Lys Cys Lys Thr 
                165                 170                 175     


Leu Gln Asn Arg Glu His Glu Thr Asn Gly Val Ala Lys Ser Asp Gln 
            180                 185                 190         


Lys Gln Glu Gln Leu Leu Leu Lys Lys Met Tyr Leu Met Leu Asp Asn 
        195                 200                 205             


Lys Arg Lys Glu Val Val His Lys Ile Ile Glu Leu Leu Asn Val Thr 
    210                 215                 220                 


Glu Leu Thr Gln Asn Ala Leu Ile Asn Asp Glu Leu Val Glu Trp Lys 
225                 230                 235                 240 


Arg Arg Gln Gln Ser Ala Cys Ile Gly Gly Pro Pro Asn Ala Cys Leu 
                245                 250                 255     


Asp Gln Leu Gln Asn Trp Phe Thr Ile Val Ala Glu Ser Leu Gln Gln 
            260                 265                 270         


Val Arg Gln Gln Leu Lys Lys Leu Glu Glu Leu Glu Gln Lys Tyr Thr 
        275                 280                 285             


Tyr Glu His Asp Pro Ile Thr Lys Asn Lys Gln Val Leu Trp Asp Arg 
    290                 295                 300                 


Thr Phe Ser Leu Phe Gln Gln Leu Ile Gln Ser Ser Phe Val Val Glu 
305                 310                 315                 320 


Arg Gln Pro Cys Met Pro Thr His Pro Gln Arg Pro Leu Val Leu Lys 
                325                 330                 335     


Thr Gly Val Gln Phe Thr Val Lys Leu Arg Leu Leu Val Lys Leu Gln 
            340                 345                 350         


Glu Leu Asn Tyr Asn Leu Lys Val Lys Val Leu Phe Asp Lys Asp Val 
        355                 360                 365             


Asn Glu Arg Asn Thr Val Lys Gly Phe Arg Lys Phe Asn Ile Leu Gly 
    370                 375                 380                 


Thr His Thr Lys Val Met Asn Met Glu Glu Ser Thr Asn Gly Ser Leu 
385                 390                 395                 400 


Ala Ala Glu Phe Arg His Leu Gln Leu Lys Glu Gln Lys Asn Ala Gly 
                405                 410                 415     


Thr Arg Thr Asn Glu Gly Pro Leu Ile Val Thr Glu Glu Leu His Ser 
            420                 425                 430         


Leu Ser Phe Glu Thr Gln Leu Cys Gln Pro Gly Leu Val Ile Asp Leu 
        435                 440                 445             


Glu Thr Thr Ser Leu Pro Val Val Val Ile Ser Asn Val Ser Gln Leu 
    450                 455                 460                 


Pro Ser Gly Trp Ala Ser Ile Leu Trp Tyr Asn Met Leu Val Ala Glu 
465                 470                 475                 480 


Pro Arg Asn Leu Ser Phe Phe Leu Thr Pro Pro Cys Ala Arg Trp Ala 
                485                 490                 495     


Gln Leu Ser Glu Val Leu Ser Trp Gln Phe Ser Ser Val Thr Lys Arg 
            500                 505                 510         


Gly Leu Asn Val Asp Gln Leu Asn Met Leu Gly Glu Lys Leu Leu Gly 
        515                 520                 525             


Pro Asn Ala Ser Pro Asp Gly Leu Ile Pro Trp Thr Arg Phe Cys Lys 
    530                 535                 540                 


Glu Asn Ile Asn Asp Lys Asn Phe Pro Phe Trp Leu Trp Ile Glu Ser 
545                 550                 555                 560 


Ile Leu Glu Leu Ile Lys Lys His Leu Leu Pro Leu Trp Asn Asp Gly 
                565                 570                 575     


Cys Ile Met Gly Phe Ile Ser Lys Glu Arg Glu Arg Ala Leu Leu Lys 
            580                 585                 590         


Asp Gln Gln Pro Gly Thr Phe Leu Leu Arg Phe Ser Glu Ser Ser Arg 
        595                 600                 605             


Glu Gly Ala Ile Thr Phe Thr Trp Val Glu Arg Ser Gln Asn Gly Gly 
    610                 615                 620                 


Glu Pro Asp Phe His Ala Val Glu Pro Tyr Thr Lys Lys Glu Leu Ser 
625                 630                 635                 640 


Ala Val Thr Phe Pro Asp Ile Ile Arg Asn Tyr Lys Val Met Ala Ala 
                645                 650                 655     


Glu Asn Ile Pro Glu Asn Pro Leu Lys Tyr Leu Tyr Pro Asn Ile Asp 
            660                 665                 670         


Lys Asp His Ala Phe Gly Lys Tyr Tyr Ser Arg Pro Lys Glu Ala Pro 
        675                 680                 685             


Glu Pro Met Glu Leu Asp Gly Pro Lys Gly Thr Gly Tyr Ile Lys Thr 
    690                 695                 700                 


Glu Leu Ile Ser Val Ser Glu Val His Pro Ser Arg Leu Gln Thr Thr 
705                 710                 715                 720 


Asp Asn Leu Leu Pro Met Ser Pro Glu Glu Phe Asp Glu Val Ser Arg 
                725                 730                 735     


Ile Val Gly Ser Val Glu Phe Asp Ser Met Met Asn Thr Val 
            740                 745                 750 


<210>  2987
<211>  712
<212>  PRT
<213>  homo sapiens

<400>  2987

Met Ser Gln Trp Tyr Glu Leu Gln Gln Leu Asp Ser Lys Phe Leu Glu 
1               5                   10                  15      


Gln Val His Gln Leu Tyr Asp Asp Ser Phe Pro Met Glu Ile Arg Gln 
            20                  25                  30          


Tyr Leu Ala Gln Trp Leu Glu Lys Gln Asp Trp Glu His Ala Ala Asn 
        35                  40                  45              


Asp Val Ser Phe Ala Thr Ile Arg Phe His Asp Leu Leu Ser Gln Leu 
    50                  55                  60                  


Asp Asp Gln Tyr Ser Arg Phe Ser Leu Glu Asn Asn Phe Leu Leu Gln 
65                  70                  75                  80  


His Asn Ile Arg Lys Ser Lys Arg Asn Leu Gln Asp Asn Phe Gln Glu 
                85                  90                  95      


Asp Pro Ile Gln Met Ser Met Ile Ile Tyr Ser Cys Leu Lys Glu Glu 
            100                 105                 110         


Arg Lys Ile Leu Glu Asn Ala Gln Arg Phe Asn Gln Ala Gln Ser Gly 
        115                 120                 125             


Asn Ile Gln Ser Thr Val Met Leu Asp Lys Gln Lys Glu Leu Asp Ser 
    130                 135                 140                 


Lys Val Arg Asn Val Lys Asp Lys Val Met Cys Ile Glu His Glu Ile 
145                 150                 155                 160 


Lys Ser Leu Glu Asp Leu Gln Asp Glu Tyr Asp Phe Lys Cys Lys Thr 
                165                 170                 175     


Leu Gln Asn Arg Glu His Glu Thr Asn Gly Val Ala Lys Ser Asp Gln 
            180                 185                 190         


Lys Gln Glu Gln Leu Leu Leu Lys Lys Met Tyr Leu Met Leu Asp Asn 
        195                 200                 205             


Lys Arg Lys Glu Val Val His Lys Ile Ile Glu Leu Leu Asn Val Thr 
    210                 215                 220                 


Glu Leu Thr Gln Asn Ala Leu Ile Asn Asp Glu Leu Val Glu Trp Lys 
225                 230                 235                 240 


Arg Arg Gln Gln Ser Ala Cys Ile Gly Gly Pro Pro Asn Ala Cys Leu 
                245                 250                 255     


Asp Gln Leu Gln Asn Trp Phe Thr Ile Val Ala Glu Ser Leu Gln Gln 
            260                 265                 270         


Val Arg Gln Gln Leu Lys Lys Leu Glu Glu Leu Glu Gln Lys Tyr Thr 
        275                 280                 285             


Tyr Glu His Asp Pro Ile Thr Lys Asn Lys Gln Val Leu Trp Asp Arg 
    290                 295                 300                 


Thr Phe Ser Leu Phe Gln Gln Leu Ile Gln Ser Ser Phe Val Val Glu 
305                 310                 315                 320 


Arg Gln Pro Cys Met Pro Thr His Pro Gln Arg Pro Leu Val Leu Lys 
                325                 330                 335     


Thr Gly Val Gln Phe Thr Val Lys Leu Arg Leu Leu Val Lys Leu Gln 
            340                 345                 350         


Glu Leu Asn Tyr Asn Leu Lys Val Lys Val Leu Phe Asp Lys Asp Val 
        355                 360                 365             


Asn Glu Arg Asn Thr Val Lys Gly Phe Arg Lys Phe Asn Ile Leu Gly 
    370                 375                 380                 


Thr His Thr Lys Val Met Asn Met Glu Glu Ser Thr Asn Gly Ser Leu 
385                 390                 395                 400 


Ala Ala Glu Phe Arg His Leu Gln Leu Lys Glu Gln Lys Asn Ala Gly 
                405                 410                 415     


Thr Arg Thr Asn Glu Gly Pro Leu Ile Val Thr Glu Glu Leu His Ser 
            420                 425                 430         


Leu Ser Phe Glu Thr Gln Leu Cys Gln Pro Gly Leu Val Ile Asp Leu 
        435                 440                 445             


Glu Thr Thr Ser Leu Pro Val Val Val Ile Ser Asn Val Ser Gln Leu 
    450                 455                 460                 


Pro Ser Gly Trp Ala Ser Ile Leu Trp Tyr Asn Met Leu Val Ala Glu 
465                 470                 475                 480 


Pro Arg Asn Leu Ser Phe Phe Leu Thr Pro Pro Cys Ala Arg Trp Ala 
                485                 490                 495     


Gln Leu Ser Glu Val Leu Ser Trp Gln Phe Ser Ser Val Thr Lys Arg 
            500                 505                 510         


Gly Leu Asn Val Asp Gln Leu Asn Met Leu Gly Glu Lys Leu Leu Gly 
        515                 520                 525             


Pro Asn Ala Ser Pro Asp Gly Leu Ile Pro Trp Thr Arg Phe Cys Lys 
    530                 535                 540                 


Glu Asn Ile Asn Asp Lys Asn Phe Pro Phe Trp Leu Trp Ile Glu Ser 
545                 550                 555                 560 


Ile Leu Glu Leu Ile Lys Lys His Leu Leu Pro Leu Trp Asn Asp Gly 
                565                 570                 575     


Cys Ile Met Gly Phe Ile Ser Lys Glu Arg Glu Arg Ala Leu Leu Lys 
            580                 585                 590         


Asp Gln Gln Pro Gly Thr Phe Leu Leu Arg Phe Ser Glu Ser Ser Arg 
        595                 600                 605             


Glu Gly Ala Ile Thr Phe Thr Trp Val Glu Arg Ser Gln Asn Gly Gly 
    610                 615                 620                 


Glu Pro Asp Phe His Ala Val Glu Pro Tyr Thr Lys Lys Glu Leu Ser 
625                 630                 635                 640 


Ala Val Thr Phe Pro Asp Ile Ile Arg Asn Tyr Lys Val Met Ala Ala 
                645                 650                 655     


Glu Asn Ile Pro Glu Asn Pro Leu Lys Tyr Leu Tyr Pro Asn Ile Asp 
            660                 665                 670         


Lys Asp His Ala Phe Gly Lys Tyr Tyr Ser Arg Pro Lys Glu Ala Pro 
        675                 680                 685             


Glu Pro Met Glu Leu Asp Gly Pro Lys Gly Thr Gly Tyr Ile Lys Thr 
    690                 695                 700                 


Glu Leu Ile Ser Val Ser Glu Val 
705                 710         


<210>  2988
<211>  769
<212>  PRT
<213>  homo sapiens

<400>  2988

Met Ala Gln Trp Asn Gln Leu Gln Gln Leu Asp Thr Arg Tyr Leu Glu 
1               5                   10                  15      


Gln Leu His Gln Leu Tyr Ser Asp Ser Phe Pro Met Glu Leu Arg Gln 
            20                  25                  30          


Phe Leu Ala Pro Trp Ile Glu Ser Gln Asp Trp Ala Tyr Ala Ala Ser 
        35                  40                  45              


Lys Glu Ser His Ala Thr Leu Val Phe His Asn Leu Leu Gly Glu Ile 
    50                  55                  60                  


Asp Gln Gln Tyr Ser Arg Phe Leu Gln Glu Ser Asn Val Leu Tyr Gln 
65                  70                  75                  80  


His Asn Leu Arg Arg Ile Lys Gln Phe Leu Gln Ser Arg Tyr Leu Glu 
                85                  90                  95      


Lys Pro Met Glu Ile Ala Arg Ile Val Ala Arg Cys Leu Trp Glu Glu 
            100                 105                 110         


Ser Arg Leu Leu Gln Thr Ala Ala Thr Ala Ala Gln Gln Gly Gly Gln 
        115                 120                 125             


Ala Asn His Pro Thr Ala Ala Val Val Thr Glu Lys Gln Gln Met Leu 
    130                 135                 140                 


Glu Gln His Leu Gln Asp Val Arg Lys Arg Val Gln Asp Leu Glu Gln 
145                 150                 155                 160 


Lys Met Lys Val Val Glu Asn Leu Gln Asp Asp Phe Asp Phe Asn Tyr 
                165                 170                 175     


Lys Thr Leu Lys Ser Gln Gly Asp Met Gln Asp Leu Asn Gly Asn Asn 
            180                 185                 190         


Gln Ser Val Thr Arg Gln Lys Met Gln Gln Leu Glu Gln Met Leu Thr 
        195                 200                 205             


Ala Leu Asp Gln Met Arg Arg Ser Ile Val Ser Glu Leu Ala Gly Leu 
    210                 215                 220                 


Leu Ser Ala Met Glu Tyr Val Gln Lys Thr Leu Thr Asp Glu Glu Leu 
225                 230                 235                 240 


Ala Asp Trp Lys Arg Arg Gln Gln Ile Ala Cys Ile Gly Gly Pro Pro 
                245                 250                 255     


Asn Ile Cys Leu Asp Arg Leu Glu Asn Trp Ile Thr Ser Leu Ala Glu 
            260                 265                 270         


Ser Gln Leu Gln Thr Arg Gln Gln Ile Lys Lys Leu Glu Glu Leu Gln 
        275                 280                 285             


Gln Lys Val Ser Tyr Lys Gly Asp Pro Ile Val Gln His Arg Pro Met 
    290                 295                 300                 


Leu Glu Glu Arg Ile Val Glu Leu Phe Arg Asn Leu Met Lys Ser Ala 
305                 310                 315                 320 


Phe Val Val Glu Arg Gln Pro Cys Met Pro Met His Pro Asp Arg Pro 
                325                 330                 335     


Leu Val Ile Lys Thr Gly Val Gln Phe Thr Thr Lys Val Arg Leu Leu 
            340                 345                 350         


Val Lys Phe Pro Glu Leu Asn Tyr Gln Leu Lys Ile Lys Val Cys Ile 
        355                 360                 365             


Asp Lys Asp Ser Gly Asp Val Ala Ala Leu Arg Gly Ser Arg Lys Phe 
    370                 375                 380                 


Asn Ile Leu Gly Thr Asn Thr Lys Val Met Asn Met Glu Glu Ser Asn 
385                 390                 395                 400 


Asn Gly Ser Leu Ser Ala Glu Phe Lys His Leu Thr Leu Arg Glu Gln 
                405                 410                 415     


Arg Cys Gly Asn Gly Gly Arg Ala Asn Cys Asp Ala Ser Leu Ile Val 
            420                 425                 430         


Thr Glu Glu Leu His Leu Ile Thr Phe Glu Thr Glu Val Tyr His Gln 
        435                 440                 445             


Gly Leu Lys Ile Asp Leu Glu Thr His Ser Leu Pro Val Val Val Ile 
    450                 455                 460                 


Ser Asn Ile Cys Gln Met Pro Asn Ala Trp Ala Ser Ile Leu Trp Tyr 
465                 470                 475                 480 


Asn Met Leu Thr Asn Asn Pro Lys Asn Val Asn Phe Phe Thr Lys Pro 
                485                 490                 495     


Pro Ile Gly Thr Trp Asp Gln Val Ala Glu Val Leu Ser Trp Gln Phe 
            500                 505                 510         


Ser Ser Thr Thr Lys Arg Gly Leu Ser Ile Glu Gln Leu Thr Thr Leu 
        515                 520                 525             


Ala Glu Lys Leu Leu Gly Pro Gly Val Asn Tyr Ser Gly Cys Gln Ile 
    530                 535                 540                 


Thr Trp Ala Lys Phe Cys Lys Glu Asn Met Ala Gly Lys Gly Phe Ser 
545                 550                 555                 560 


Phe Trp Val Trp Leu Asp Asn Ile Ile Asp Leu Val Lys Lys Tyr Ile 
                565                 570                 575     


Leu Ala Leu Trp Asn Glu Gly Tyr Ile Met Gly Phe Ile Ser Lys Glu 
            580                 585                 590         


Arg Glu Arg Ala Ile Leu Ser Thr Lys Pro Pro Gly Thr Phe Leu Leu 
        595                 600                 605             


Arg Phe Ser Glu Ser Ser Lys Glu Gly Gly Val Thr Phe Thr Trp Val 
    610                 615                 620                 


Glu Lys Asp Ile Ser Gly Lys Thr Gln Ile Gln Ser Val Glu Pro Tyr 
625                 630                 635                 640 


Thr Lys Gln Gln Leu Asn Asn Met Ser Phe Ala Glu Ile Ile Met Gly 
                645                 650                 655     


Tyr Lys Ile Met Asp Ala Thr Asn Ile Leu Val Ser Pro Leu Val Tyr 
            660                 665                 670         


Leu Tyr Pro Asp Ile Pro Lys Glu Glu Ala Phe Gly Lys Tyr Cys Arg 
        675                 680                 685             


Pro Glu Ser Gln Glu His Pro Glu Ala Asp Pro Gly Ala Ala Pro Tyr 
    690                 695                 700                 


Leu Lys Thr Lys Phe Ile Cys Val Thr Pro Thr Thr Cys Ser Asn Thr 
705                 710                 715                 720 


Ile Asp Leu Pro Met Ser Pro Arg Thr Leu Asp Ser Leu Met Gln Phe 
                725                 730                 735     


Gly Asn Asn Gly Glu Gly Ala Glu Pro Ser Ala Gly Gly Gln Phe Glu 
            740                 745                 750         


Ser Leu Thr Phe Asp Met Glu Leu Thr Ser Glu Cys Ala Thr Ser Pro 
        755                 760                 765             


Met 
    


<210>  2989
<211>  770
<212>  PRT
<213>  homo sapiens

<400>  2989

Met Ala Gln Trp Asn Gln Leu Gln Gln Leu Asp Thr Arg Tyr Leu Glu 
1               5                   10                  15      


Gln Leu His Gln Leu Tyr Ser Asp Ser Phe Pro Met Glu Leu Arg Gln 
            20                  25                  30          


Phe Leu Ala Pro Trp Ile Glu Ser Gln Asp Trp Ala Tyr Ala Ala Ser 
        35                  40                  45              


Lys Glu Ser His Ala Thr Leu Val Phe His Asn Leu Leu Gly Glu Ile 
    50                  55                  60                  


Asp Gln Gln Tyr Ser Arg Phe Leu Gln Glu Ser Asn Val Leu Tyr Gln 
65                  70                  75                  80  


His Asn Leu Arg Arg Ile Lys Gln Phe Leu Gln Ser Arg Tyr Leu Glu 
                85                  90                  95      


Lys Pro Met Glu Ile Ala Arg Ile Val Ala Arg Cys Leu Trp Glu Glu 
            100                 105                 110         


Ser Arg Leu Leu Gln Thr Ala Ala Thr Ala Ala Gln Gln Gly Gly Gln 
        115                 120                 125             


Ala Asn His Pro Thr Ala Ala Val Val Thr Glu Lys Gln Gln Met Leu 
    130                 135                 140                 


Glu Gln His Leu Gln Asp Val Arg Lys Arg Val Gln Asp Leu Glu Gln 
145                 150                 155                 160 


Lys Met Lys Val Val Glu Asn Leu Gln Asp Asp Phe Asp Phe Asn Tyr 
                165                 170                 175     


Lys Thr Leu Lys Ser Gln Gly Asp Met Gln Asp Leu Asn Gly Asn Asn 
            180                 185                 190         


Gln Ser Val Thr Arg Gln Lys Met Gln Gln Leu Glu Gln Met Leu Thr 
        195                 200                 205             


Ala Leu Asp Gln Met Arg Arg Ser Ile Val Ser Glu Leu Ala Gly Leu 
    210                 215                 220                 


Leu Ser Ala Met Glu Tyr Val Gln Lys Thr Leu Thr Asp Glu Glu Leu 
225                 230                 235                 240 


Ala Asp Trp Lys Arg Arg Gln Gln Ile Ala Cys Ile Gly Gly Pro Pro 
                245                 250                 255     


Asn Ile Cys Leu Asp Arg Leu Glu Asn Trp Ile Thr Ser Leu Ala Glu 
            260                 265                 270         


Ser Gln Leu Gln Thr Arg Gln Gln Ile Lys Lys Leu Glu Glu Leu Gln 
        275                 280                 285             


Gln Lys Val Ser Tyr Lys Gly Asp Pro Ile Val Gln His Arg Pro Met 
    290                 295                 300                 


Leu Glu Glu Arg Ile Val Glu Leu Phe Arg Asn Leu Met Lys Ser Ala 
305                 310                 315                 320 


Phe Val Val Glu Arg Gln Pro Cys Met Pro Met His Pro Asp Arg Pro 
                325                 330                 335     


Leu Val Ile Lys Thr Gly Val Gln Phe Thr Thr Lys Val Arg Leu Leu 
            340                 345                 350         


Val Lys Phe Pro Glu Leu Asn Tyr Gln Leu Lys Ile Lys Val Cys Ile 
        355                 360                 365             


Asp Lys Asp Ser Gly Asp Val Ala Ala Leu Arg Gly Ser Arg Lys Phe 
    370                 375                 380                 


Asn Ile Leu Gly Thr Asn Thr Lys Val Met Asn Met Glu Glu Ser Asn 
385                 390                 395                 400 


Asn Gly Ser Leu Ser Ala Glu Phe Lys His Leu Thr Leu Arg Glu Gln 
                405                 410                 415     


Arg Cys Gly Asn Gly Gly Arg Ala Asn Cys Asp Ala Ser Leu Ile Val 
            420                 425                 430         


Thr Glu Glu Leu His Leu Ile Thr Phe Glu Thr Glu Val Tyr His Gln 
        435                 440                 445             


Gly Leu Lys Ile Asp Leu Glu Thr His Ser Leu Pro Val Val Val Ile 
    450                 455                 460                 


Ser Asn Ile Cys Gln Met Pro Asn Ala Trp Ala Ser Ile Leu Trp Tyr 
465                 470                 475                 480 


Asn Met Leu Thr Asn Asn Pro Lys Asn Val Asn Phe Phe Thr Lys Pro 
                485                 490                 495     


Pro Ile Gly Thr Trp Asp Gln Val Ala Glu Val Leu Ser Trp Gln Phe 
            500                 505                 510         


Ser Ser Thr Thr Lys Arg Gly Leu Ser Ile Glu Gln Leu Thr Thr Leu 
        515                 520                 525             


Ala Glu Lys Leu Leu Gly Pro Gly Val Asn Tyr Ser Gly Cys Gln Ile 
    530                 535                 540                 


Thr Trp Ala Lys Phe Cys Lys Glu Asn Met Ala Gly Lys Gly Phe Ser 
545                 550                 555                 560 


Phe Trp Val Trp Leu Asp Asn Ile Ile Asp Leu Val Lys Lys Tyr Ile 
                565                 570                 575     


Leu Ala Leu Trp Asn Glu Gly Tyr Ile Met Gly Phe Ile Ser Lys Glu 
            580                 585                 590         


Arg Glu Arg Ala Ile Leu Ser Thr Lys Pro Pro Gly Thr Phe Leu Leu 
        595                 600                 605             


Arg Phe Ser Glu Ser Ser Lys Glu Gly Gly Val Thr Phe Thr Trp Val 
    610                 615                 620                 


Glu Lys Asp Ile Ser Gly Lys Thr Gln Ile Gln Ser Val Glu Pro Tyr 
625                 630                 635                 640 


Thr Lys Gln Gln Leu Asn Asn Met Ser Phe Ala Glu Ile Ile Met Gly 
                645                 650                 655     


Tyr Lys Ile Met Asp Ala Thr Asn Ile Leu Val Ser Pro Leu Val Tyr 
            660                 665                 670         


Leu Tyr Pro Asp Ile Pro Lys Glu Glu Ala Phe Gly Lys Tyr Cys Arg 
        675                 680                 685             


Pro Glu Ser Gln Glu His Pro Glu Ala Asp Pro Gly Ser Ala Ala Pro 
    690                 695                 700                 


Tyr Leu Lys Thr Lys Phe Ile Cys Val Thr Pro Thr Thr Cys Ser Asn 
705                 710                 715                 720 


Thr Ile Asp Leu Pro Met Ser Pro Arg Thr Leu Asp Ser Leu Met Gln 
                725                 730                 735     


Phe Gly Asn Asn Gly Glu Gly Ala Glu Pro Ser Ala Gly Gly Gln Phe 
            740                 745                 750         


Glu Ser Leu Thr Phe Asp Met Glu Leu Thr Ser Glu Cys Ala Thr Ser 
        755                 760                 765             


Pro Met 
    770 


<210>  2990
<211>  356
<212>  PRT
<213>  homo sapiens

<400>  2990

Met Gly Leu Leu Arg Ile Met Met Pro Pro Lys Leu Gln Leu Leu Ala 
1               5                   10                  15      


Val Val Ala Phe Ala Val Ala Met Leu Phe Leu Glu Asn Gln Ile Gln 
            20                  25                  30          


Lys Leu Glu Glu Ser Arg Ser Lys Leu Glu Arg Ala Ile Ala Arg His 
        35                  40                  45              


Glu Val Arg Glu Ile Glu Gln Arg His Thr Met Asp Gly Pro Arg Gln 
    50                  55                  60                  


Asp Ala Thr Leu Asp Glu Glu Glu Asp Met Val Ile Ile Tyr Asn Arg 
65                  70                  75                  80  


Val Pro Lys Thr Ala Ser Thr Ser Phe Thr Asn Ile Ala Tyr Asp Leu 
                85                  90                  95      


Cys Ala Lys Asn Lys Tyr His Val Leu His Ile Asn Thr Thr Lys Asn 
            100                 105                 110         


Asn Pro Val Met Ser Leu Gln Asp Gln Val Arg Phe Val Lys Asn Ile 
        115                 120                 125             


Thr Ser Trp Lys Glu Met Lys Pro Gly Phe Tyr His Gly His Val Ser 
    130                 135                 140                 


Tyr Leu Asp Phe Ala Lys Phe Gly Val Lys Lys Lys Pro Ile Tyr Ile 
145                 150                 155                 160 


Asn Val Ile Arg Asp Pro Ile Glu Arg Leu Val Ser Tyr Tyr Tyr Phe 
                165                 170                 175     


Leu Arg Phe Gly Asp Asp Tyr Arg Pro Gly Leu Arg Arg Arg Lys Gln 
            180                 185                 190         


Gly Asp Lys Lys Thr Phe Asp Glu Cys Val Ala Glu Gly Gly Ser Asp 
        195                 200                 205             


Cys Ala Pro Glu Lys Leu Trp Leu Gln Ile Pro Phe Phe Cys Gly His 
    210                 215                 220                 


Ser Ser Glu Cys Trp Asn Val Gly Ser Arg Trp Ala Met Asp Gln Ala 
225                 230                 235                 240 


Lys Tyr Asn Leu Ile Asn Glu Tyr Phe Leu Val Gly Val Thr Glu Glu 
                245                 250                 255     


Leu Glu Asp Phe Ile Met Leu Leu Glu Ala Ala Leu Pro Arg Phe Phe 
            260                 265                 270         


Arg Gly Ala Thr Glu Leu Tyr Arg Thr Gly Lys Lys Ser His Leu Arg 
        275                 280                 285             


Lys Thr Thr Glu Lys Lys Leu Pro Thr Lys Gln Thr Ile Ala Lys Leu 
    290                 295                 300                 


Gln Gln Ser Asp Ile Trp Lys Met Glu Asn Glu Phe Tyr Glu Phe Ala 
305                 310                 315                 320 


Leu Glu Gln Phe Gln Phe Ile Arg Ala His Ala Val Arg Glu Lys Asp 
                325                 330                 335     


Gly Asp Leu Tyr Ile Leu Ala Gln Asn Phe Phe Tyr Glu Lys Ile Tyr 
            340                 345                 350         


Pro Lys Ser Asn 
        355     


<210>  2991
<211>  430
<212>  PRT
<213>  homo sapiens

<400>  2991

Met Asp Glu Gln Pro Arg Leu Met His Ser His Ala Gly Val Gly Met 
1               5                   10                  15      


Ala Gly His Pro Gly Leu Ser Gln His Leu Gln Asp Gly Ala Gly Gly 
            20                  25                  30          


Thr Glu Gly Glu Gly Gly Arg Lys Gln Asp Ile Gly Asp Ile Leu Gln 
        35                  40                  45              


Gln Ile Met Thr Ile Thr Asp Gln Ser Leu Asp Glu Ala Gln Ala Arg 
    50                  55                  60                  


Lys His Ala Leu Asn Cys His Arg Met Lys Pro Ala Leu Phe Asn Val 
65                  70                  75                  80  


Leu Cys Glu Ile Lys Glu Lys Thr Val Leu Ser Ile Arg Gly Ala Gln 
                85                  90                  95      


Glu Glu Glu Pro Thr Asp Pro Gln Leu Met Arg Leu Asp Asn Met Leu 
            100                 105                 110         


Leu Ala Glu Gly Val Ala Gly Pro Glu Lys Gly Gly Gly Ser Ala Ala 
        115                 120                 125             


Ala Ala Ala Ala Ala Ala Ala Ser Gly Gly Ala Gly Ser Asp Asn Ser 
    130                 135                 140                 


Val Glu His Ser Asp Tyr Arg Ala Lys Leu Ser Gln Ile Arg Gln Ile 
145                 150                 155                 160 


Tyr His Thr Glu Leu Glu Lys Tyr Glu Gln Ala Cys Asn Glu Phe Thr 
                165                 170                 175     


Thr His Val Met Asn Leu Leu Arg Glu Gln Ser Arg Thr Arg Pro Ile 
            180                 185                 190         


Ser Pro Lys Glu Ile Glu Arg Met Val Ser Ile Ile His Arg Lys Phe 
        195                 200                 205             


Ser Ser Ile Gln Met Gln Leu Lys Gln Ser Thr Cys Glu Ala Val Met 
    210                 215                 220                 


Ile Leu Arg Ser Arg Phe Leu Asp Ala Arg Arg Lys Arg Arg Asn Phe 
225                 230                 235                 240 


Asn Lys Gln Ala Thr Glu Ile Leu Asn Glu Tyr Phe Tyr Ser His Leu 
                245                 250                 255     


Ser Asn Pro Tyr Pro Ser Glu Glu Ala Lys Glu Glu Leu Ala Lys Lys 
            260                 265                 270         


Cys Gly Ile Thr Val Ser Gln Val Ser Asn Trp Phe Gly Asn Lys Arg 
        275                 280                 285             


Ile Arg Tyr Lys Lys Asn Ile Gly Lys Phe Gln Glu Glu Ala Asn Ile 
    290                 295                 300                 


Tyr Ala Ala Lys Thr Ala Val Thr Ala Thr Asn Val Ser Ala His Gly 
305                 310                 315                 320 


Ser Gln Ala Asn Ser Pro Ser Thr Pro Asn Ser Ala Gly Ser Ser Ser 
                325                 330                 335     


Ser Phe Asn Met Ser Asn Ser Gly Asp Leu Phe Met Ser Val Gln Ser 
            340                 345                 350         


Leu Asn Gly Asp Ser Tyr Gln Gly Ala Gln Val Gly Ala Asn Val Gln 
        355                 360                 365             


Ser Gln Val Asp Thr Leu Arg His Val Ile Ser Gln Thr Gly Gly Tyr 
    370                 375                 380                 


Ser Asp Gly Leu Ala Ala Ser Gln Met Tyr Ser Pro Gln Gly Ile Ser 
385                 390                 395                 400 


Ala Asn Gly Gly Trp Gln Asp Ala Thr Thr Pro Ser Ser Val Thr Ser 
                405                 410                 415     


Pro Thr Glu Gly Pro Gly Ser Val His Ser Asp Thr Ser Asn 
            420                 425                 430 


<210>  2992
<211>  258
<212>  PRT
<213>  homo sapiens

<400>  2992

Met Leu Leu Val Leu Val Val Leu Ile Pro Val Leu Val Ser Ser Gly 
1               5                   10                  15      


Gly Pro Glu Gly His Tyr Glu Met Leu Gly Thr Cys Arg Met Val Cys 
            20                  25                  30          


Asp Pro Tyr Pro Ala Arg Gly Pro Gly Ala Gly Ala Arg Thr Asp Gly 
        35                  40                  45              


Gly Asp Ala Leu Ser Glu Gln Ser Gly Ala Pro Pro Pro Ser Thr Leu 
    50                  55                  60                  


Val Gln Gly Pro Gln Gly Lys Pro Gly Arg Thr Gly Lys Pro Gly Pro 
65                  70                  75                  80  


Pro Gly Pro Pro Gly Asp Pro Gly Pro Pro Gly Pro Val Gly Pro Pro 
                85                  90                  95      


Gly Glu Lys Gly Glu Pro Gly Lys Pro Gly Pro Pro Gly Leu Pro Gly 
            100                 105                 110         


Ala Gly Gly Ser Gly Ala Ile Ser Thr Ala Thr Tyr Thr Thr Val Pro 
        115                 120                 125             


Arg Val Ala Phe Tyr Ala Gly Leu Lys Asn Pro His Glu Gly Tyr Glu 
    130                 135                 140                 


Val Leu Lys Phe Asp Asp Val Val Thr Asn Leu Gly Asn Asn Tyr Asp 
145                 150                 155                 160 


Ala Ala Ser Gly Lys Phe Thr Cys Asn Ile Pro Gly Thr Tyr Phe Phe 
                165                 170                 175     


Thr Tyr His Val Leu Met Arg Gly Gly Asp Gly Thr Ser Met Trp Ala 
            180                 185                 190         


Asp Leu Cys Lys Asn Gly Gln Val Arg Ala Ser Ala Ile Ala Gln Asp 
        195                 200                 205             


Ala Asp Gln Asn Tyr Asp Tyr Ala Ser Asn Ser Val Ile Leu His Leu 
    210                 215                 220                 


Asp Ala Gly Asp Glu Val Phe Ile Lys Leu Asp Gly Gly Lys Ala His 
225                 230                 235                 240 


Gly Gly Asn Ser Asn Lys Tyr Ser Thr Phe Ser Gly Phe Ile Ile Tyr 
                245                 250                 255     


Ser Asp 
        


<210>  2993
<211>  583
<212>  PRT
<213>  homo sapiens

<400>  2993

Met Glu Ser Lys Gly Ala Ser Ser Cys Arg Leu Leu Phe Cys Leu Leu 
1               5                   10                  15      


Ile Ser Ala Thr Val Phe Arg Pro Gly Leu Gly Trp Tyr Thr Val Asn 
            20                  25                  30          


Ser Ala Tyr Gly Asp Thr Ile Ile Ile Pro Cys Arg Leu Asp Val Pro 
        35                  40                  45              


Gln Asn Leu Met Phe Gly Lys Trp Lys Tyr Glu Lys Pro Asp Gly Ser 
    50                  55                  60                  


Pro Val Phe Ile Ala Phe Arg Ser Ser Thr Lys Lys Ser Val Gln Tyr 
65                  70                  75                  80  


Asp Asp Val Pro Glu Tyr Lys Asp Arg Leu Asn Leu Ser Glu Asn Tyr 
                85                  90                  95      


Thr Leu Ser Ile Ser Asn Ala Arg Ile Ser Asp Glu Lys Arg Phe Val 
            100                 105                 110         


Cys Met Leu Val Thr Glu Asp Asn Val Phe Glu Ala Pro Thr Ile Val 
        115                 120                 125             


Lys Val Phe Lys Gln Pro Ser Lys Pro Glu Ile Val Ser Lys Ala Leu 
    130                 135                 140                 


Phe Leu Glu Thr Glu Gln Leu Lys Lys Leu Gly Asp Cys Ile Ser Glu 
145                 150                 155                 160 


Asp Ser Tyr Pro Asp Gly Asn Ile Thr Trp Tyr Arg Asn Gly Lys Val 
                165                 170                 175     


Leu His Pro Leu Glu Gly Ala Val Val Ile Ile Phe Lys Lys Glu Met 
            180                 185                 190         


Asp Pro Val Thr Gln Leu Tyr Thr Met Thr Ser Thr Leu Glu Tyr Lys 
        195                 200                 205             


Thr Thr Lys Ala Asp Ile Gln Met Pro Phe Thr Cys Ser Val Thr Tyr 
    210                 215                 220                 


Tyr Gly Pro Ser Gly Gln Lys Thr Ile His Ser Glu Gln Ala Val Phe 
225                 230                 235                 240 


Asp Ile Tyr Tyr Pro Thr Glu Gln Val Thr Ile Gln Val Leu Pro Pro 
                245                 250                 255     


Lys Asn Ala Ile Lys Glu Gly Asp Asn Ile Thr Leu Lys Cys Leu Gly 
            260                 265                 270         


Asn Gly Asn Pro Pro Pro Glu Glu Phe Leu Phe Tyr Leu Pro Gly Gln 
        275                 280                 285             


Pro Glu Gly Ile Arg Ser Ser Asn Thr Tyr Thr Leu Thr Asp Val Arg 
    290                 295                 300                 


Arg Asn Ala Thr Gly Asp Tyr Lys Cys Ser Leu Ile Asp Lys Lys Ser 
305                 310                 315                 320 


Met Ile Ala Ser Thr Ala Ile Thr Val His Tyr Leu Asp Leu Ser Leu 
                325                 330                 335     


Asn Pro Ser Gly Glu Val Thr Arg Gln Ile Gly Asp Ala Leu Pro Val 
            340                 345                 350         


Ser Cys Thr Ile Ser Ala Ser Arg Asn Ala Thr Val Val Trp Met Lys 
        355                 360                 365             


Asp Asn Ile Arg Leu Arg Ser Ser Pro Ser Phe Ser Ser Leu His Tyr 
    370                 375                 380                 


Gln Asp Ala Gly Asn Tyr Val Cys Glu Thr Ala Leu Gln Glu Val Glu 
385                 390                 395                 400 


Gly Leu Lys Lys Arg Glu Ser Leu Thr Leu Ile Val Glu Gly Lys Pro 
                405                 410                 415     


Gln Ile Lys Met Thr Lys Lys Thr Asp Pro Ser Gly Leu Ser Lys Thr 
            420                 425                 430         


Ile Ile Cys His Val Glu Gly Phe Pro Lys Pro Ala Ile Gln Trp Thr 
        435                 440                 445             


Ile Thr Gly Ser Gly Ser Val Ile Asn Gln Thr Glu Glu Ser Pro Tyr 
    450                 455                 460                 


Ile Asn Gly Arg Tyr Tyr Ser Lys Ile Ile Ile Ser Pro Glu Glu Asn 
465                 470                 475                 480 


Val Thr Leu Thr Cys Thr Ala Glu Asn Gln Leu Glu Arg Thr Val Asn 
                485                 490                 495     


Ser Leu Asn Val Ser Ala Ile Ser Ile Pro Glu His Asp Glu Ala Asp 
            500                 505                 510         


Glu Ile Ser Asp Glu Asn Arg Glu Lys Val Asn Asp Gln Ala Lys Leu 
        515                 520                 525             


Ile Val Gly Ile Val Val Gly Leu Leu Leu Ala Ala Leu Val Ala Gly 
    530                 535                 540                 


Val Val Tyr Trp Leu Tyr Met Lys Lys Ser Lys Thr Ala Ser Lys His 
545                 550                 555                 560 


Val Asn Lys Asp Leu Gly Asn Met Glu Glu Asn Lys Lys Leu Glu Glu 
                565                 570                 575     


Asn Asn His Lys Thr Glu Ala 
            580             


<210>  2994
<211>  671
<212>  PRT
<213>  homo sapiens

<400>  2994

Met Glu Thr Ser Arg Ser Arg Gly Gly Gly Gly Ala Val Ser Glu Arg 
1               5                   10                  15      


Gly Gly Ala Gly Ala Ser Val Gly Val Cys Arg Arg Lys Ala Glu Ala 
            20                  25                  30          


Gly Ala Gly Thr Gly Thr Leu Ala Ala Asp Met Asp Leu His Cys Asp 
        35                  40                  45              


Cys Ala Ala Glu Thr Pro Ala Ala Glu Pro Pro Ser Gly Lys Ile Asn 
    50                  55                  60                  


Lys Ala Ala Phe Lys Leu Phe Lys Lys Arg Lys Ser Gly Gly Thr Met 
65                  70                  75                  80  


Pro Ser Ile Phe Gly Val Lys Asn Lys Gly Asp Gly Lys Ser Ser Gly 
                85                  90                  95      


Pro Thr Gly Leu Val Arg Ser Arg Thr His Asp Gly Leu Ala Glu Val 
            100                 105                 110         


Leu Val Leu Glu Ser Gly Arg Lys Glu Glu Pro Arg Gly Gly Gly Asp 
        115                 120                 125             


Ser Gly Gly Gly Gly Gly Gly Arg Pro Asn Pro Gly Pro Pro Arg Ala 
    130                 135                 140                 


Ala Gly Pro Gly Gly Gly Ser Leu Ala Ser Ser Ser Val Ala Lys Ser 
145                 150                 155                 160 


His Ser Phe Phe Ser Leu Leu Lys Lys Asn Gly Arg Ser Glu Asn Gly 
                165                 170                 175     


Lys Gly Glu Pro Val Asp Ala Ser Lys Ala Gly Gly Lys Gln Lys Arg 
            180                 185                 190         


Gly Leu Arg Gly Leu Phe Ser Gly Met Arg Trp His Arg Lys Asp Lys 
        195                 200                 205             


Arg Ala Lys Ala Glu Ala Ala Glu Gly Arg Ala Pro Gly Gly Gly Leu 
    210                 215                 220                 


Ile Leu Pro Gly Ser Leu Thr Ala Ser Leu Glu Cys Val Lys Glu Glu 
225                 230                 235                 240 


Thr Pro Arg Ala Ala Arg Glu Pro Glu Glu Pro Ser Gln Asp Ala Pro 
                245                 250                 255     


Arg Asp Pro Ala Gly Glu Pro Ala Gly Gly Glu Glu Val Pro Ala Pro 
            260                 265                 270         


Ala Asp Arg Ala Pro Ala Arg Ser Cys Arg Glu Ala Glu Gly Leu Ala 
        275                 280                 285             


His Pro Gly Asp Thr Gly Ala Arg Gly Glu Asp Ala Ala Gly His Arg 
    290                 295                 300                 


Arg Ala Glu Pro Gly Pro Gly Glu Val Arg Thr Ala Glu Asp Ala Ser 
305                 310                 315                 320 


Arg Thr Gly Ala Val Pro Val Lys Thr Val Pro Leu Val Asp Ser Glu 
                325                 330                 335     


Gly Gly Ser Gly Arg Ala Pro Ala Ala Pro Asp Pro Ala Ser Val Asp 
            340                 345                 350         


Pro Pro Ser Asp Pro Ser Ala Asp Arg Ile Cys Leu Met Phe Ser Asp 
        355                 360                 365             


Val Thr Ser Leu Lys Ser Phe Asp Ser Leu Thr Gly Cys Gly Asp Ile 
    370                 375                 380                 


Ile Ala Asp Gln Glu Glu Glu Ala Gly Pro Ser Cys Asp Lys His Val 
385                 390                 395                 400 


Pro Gly Pro Gly Lys Pro Ala Leu Ser Lys Lys Asn Pro Gly Val Val 
                405                 410                 415     


Ala Tyr Gln Gly Gly Gly Glu Glu Met Ala Ser Pro Asp Glu Val Asp 
            420                 425                 430         


Asp Thr Tyr Leu Gln Glu Phe Trp Asp Met Leu Ser Gln Thr Glu Glu 
        435                 440                 445             


Gln Gly Pro Glu Pro Gln Glu Gly Ala Ala Lys Val Ala Ala Ala Leu 
    450                 455                 460                 


Glu Thr Lys Val Val Pro Glu Thr Pro Lys Asp Thr Arg Cys Val Glu 
465                 470                 475                 480 


Ala Ala Lys Asp Ala Ser Ser Val Lys Arg Arg Arg Leu Asn Arg Ile 
                485                 490                 495     


Pro Ile Glu Pro His Pro Lys Glu Glu Pro Lys His Pro Glu Lys Glu 
            500                 505                 510         


Gln Gln Glu Gly Val Pro Asn Ser Asp Glu Gly Tyr Trp Asp Ser Thr 
        515                 520                 525             


Thr Pro Gly Pro Glu Glu Asp Ser Ser Ser Ser Gly Lys Lys Ala Gly 
    530                 535                 540                 


Ile Pro Arg Asp Ser Tyr Ser Gly Asp Ala Leu Tyr Asp Leu Tyr Ala 
545                 550                 555                 560 


Asp Pro Asp Gly Ser Pro Ala Thr Leu Pro Gly Gly Lys Asp Asn Glu 
                565                 570                 575     


Glu Thr Ser Ser Leu Ser Arg Leu Lys Pro Val Ser Pro Gly Thr Ile 
            580                 585                 590         


Thr Cys Pro Leu Arg Thr Pro Gly Ser Leu Leu Lys Asp Ser Lys Ile 
        595                 600                 605             


Pro Ile Ser Ile Lys His Leu Thr Asn Leu Pro Ser Ser His Pro Val 
    610                 615                 620                 


Val His Gln Gln Pro Ser Arg Ser Glu Met Pro Arg Thr Lys Ile Pro 
625                 630                 635                 640 


Val Ser Lys Val Leu Val Arg Arg Val Ser Asn Arg Gly Leu Ala Gly 
                645                 650                 655     


Thr Thr Ile Arg Ala Thr Ala Cys His Asp Ser Ala Lys Lys Leu 
            660                 665                 670     


<210>  2995
<211>  325
<212>  PRT
<213>  homo sapiens

<400>  2995

Met Glu Gly Leu Glu Glu Asn Gly Gly Val Val Gln Val Gly Glu Leu 
1               5                   10                  15      


Leu Pro Cys Lys Ile Cys Gly Arg Thr Phe Phe Pro Val Ala Leu Lys 
            20                  25                  30          


Lys His Gly Pro Ile Cys Gln Lys Thr Ala Thr Lys Lys Arg Lys Thr 
        35                  40                  45              


Phe Asp Ser Ser Arg Gln Arg Ala Glu Gly Thr Asp Ile Pro Thr Val 
    50                  55                  60                  


Lys Pro Leu Lys Pro Arg Pro Glu Pro Pro Lys Lys Pro Ser Asn Trp 
65                  70                  75                  80  


Arg Arg Lys His Glu Glu Phe Ile Ala Thr Ile Arg Ala Ala Lys Gly 
                85                  90                  95      


Leu Asp Gln Ala Leu Lys Glu Gly Gly Lys Leu Pro Pro Pro Pro Pro 
            100                 105                 110         


Pro Ser Tyr Asp Pro Asp Tyr Ile Gln Cys Pro Tyr Cys Gln Arg Arg 
        115                 120                 125             


Phe Asn Glu Asn Ala Ala Asp Arg His Ile Asn Phe Cys Lys Glu Gln 
    130                 135                 140                 


Ala Ala Arg Ile Ser Asn Lys Gly Lys Phe Ser Thr Asp Thr Lys Gly 
145                 150                 155                 160 


Lys Pro Thr Ser Arg Thr Gln Val Tyr Lys Pro Pro Ala Leu Lys Lys 
                165                 170                 175     


Ser Asn Ser Pro Gly Thr Ala Ser Ser Gly Ser Ser Arg Leu Pro Gln 
            180                 185                 190         


Pro Ser Gly Ala Gly Lys Thr Val Val Gly Val Pro Ser Gly Lys Val 
        195                 200                 205             


Ser Ser Ser Ser Ser Ser Leu Gly Asn Lys Leu Gln Thr Leu Ser Pro 
    210                 215                 220                 


Ser His Lys Gly Ile Ala Ala Pro His Ala Gly Ala Asn Val Lys Pro 
225                 230                 235                 240 


Arg Asn Ser Thr Pro Pro Ser Leu Ala Arg Asn Pro Ala Pro Gly Val 
                245                 250                 255     


Leu Thr Asn Lys Arg Lys Thr Tyr Thr Glu Ser Tyr Ile Ala Arg Pro 
            260                 265                 270         


Asp Gly Asp Cys Ala Ser Ser Leu Asn Gly Gly Asn Ile Lys Gly Ile 
        275                 280                 285             


Glu Gly His Ser Pro Gly Asn Leu Pro Lys Phe Cys His Glu Cys Gly 
    290                 295                 300                 


Thr Lys Tyr Pro Val Glu Trp Ala Lys Phe Cys Cys Glu Cys Gly Ile 
305                 310                 315                 320 


Arg Arg Met Ile Leu 
                325 


<210>  2996
<211>  826
<212>  PRT
<213>  homo sapiens

<400>  2996

Met Ala Arg Leu Cys Arg Arg Val Pro Cys Thr Leu Leu Leu Gly Leu 
1               5                   10                  15      


Ala Val Val Leu Leu Lys Ala Arg Leu Val Pro Ala Ala Ala Arg Ala 
            20                  25                  30          


Glu Leu Ser Arg Ser Asp Leu Ser Leu Ile Gln Gln Gln Gln Gln Gln 
        35                  40                  45              


Gln Gln Gln Gln Gln Gln Gln Gln Lys Gln Leu Glu Glu Ala Glu Glu 
    50                  55                  60                  


Glu Arg Thr Glu Val Pro Gly Ala Thr Ser Thr Leu Thr Val Pro Val 
65                  70                  75                  80  


Ser Val Phe Met Leu Lys Val Gln Val Asn Asp Ile Ile Ser Arg Gln 
                85                  90                  95      


Tyr Leu Ser Gln Ala Val Val Glu Val Phe Val Asn Tyr Thr Lys Thr 
            100                 105                 110         


Asn Ser Thr Val Thr Lys Ser Asn Gly Ala Val Leu Ile Lys Val Pro 
        115                 120                 125             


Tyr Lys Leu Gly Leu Ser Leu Thr Ile Ile Ala Tyr Lys Asp Gly Tyr 
    130                 135                 140                 


Val Leu Thr Pro Leu Pro Trp Lys Thr Arg Arg Met Pro Ile Tyr Ser 
145                 150                 155                 160 


Ser Val Thr Leu Ser Leu Phe Pro Gln Ser Gln Ala Asn Ile Trp Leu 
                165                 170                 175     


Phe Glu Asp Thr Val Leu Ile Thr Gly Lys Leu Ala Asp Ala Lys Ser 
            180                 185                 190         


Gln Pro Ser Val Gln Phe Ser Lys Ala Leu Ile Lys Leu Pro Asp Asn 
        195                 200                 205             


His His Ile Ser Asn Val Thr Gly Tyr Leu Thr Val Leu Gln Gln Phe 
    210                 215                 220                 


Leu Lys Val Asp Asn Phe Leu His Thr Thr Gly Ile Thr Leu Asn Lys 
225                 230                 235                 240 


Pro Gly Phe Glu Asn Ile Glu Leu Thr Pro Leu Ala Ala Ile Cys Val 
                245                 250                 255     


Lys Ile Tyr Ser Gly Gly Lys Glu Leu Lys Val Asn Gly Ser Ile Gln 
            260                 265                 270         


Val Ser Leu Pro Leu Leu Arg Leu Asn Asp Ile Ser Ala Gly Asp Arg 
        275                 280                 285             


Ile Pro Ala Trp Thr Phe Asp Met Asn Thr Gly Ala Trp Val Asn His 
    290                 295                 300                 


Gly Arg Gly Met Val Lys Glu His Asn Asn His Leu Ile Trp Thr Tyr 
305                 310                 315                 320 


Asp Ala Pro His Leu Gly Tyr Trp Ile Ala Ala Pro Leu Pro Gly Thr 
                325                 330                 335     


Arg Gly Ser Gly Ile Asn Glu Asp Ser Lys Asp Ile Thr Ala Tyr His 
            340                 345                 350         


Thr Val Phe Leu Thr Ala Ile Leu Gly Gly Thr Ile Val Ile Val Ile 
        355                 360                 365             


Gly Phe Phe Ala Val Leu Leu Cys Tyr Cys Arg Asp Lys Cys Gly Thr 
    370                 375                 380                 


Pro Gln Lys Arg Glu Arg Asn Ile Thr Lys Leu Glu Val Leu Lys Arg 
385                 390                 395                 400 


Asp Gln Thr Thr Ser Thr Thr His Ile Asn His Ile Ser Thr Val Lys 
                405                 410                 415     


Val Ala Leu Lys Ala Glu Asp Lys Ser Gln Leu Phe Asn Ala Lys Asn 
            420                 425                 430         


Ser Ser Tyr Ser Pro Gln Lys Lys Glu Pro Ser Lys Ala Glu Thr Glu 
        435                 440                 445             


Glu Arg Val Ser Met Val Lys Thr Arg Asp Asp Phe Lys Ile Tyr Asn 
    450                 455                 460                 


Glu Asp Val Ser Phe Leu Ser Val Asn Gln Asn Asn Tyr Ser Arg Asn 
465                 470                 475                 480 


Pro Thr Gln Ser Leu Glu Pro Asn Val Gly Ser Lys Gln Pro Lys His 
                485                 490                 495     


Ile Asn Asn Asn Leu Ser Ser Ser Leu Gly Asp Ala Gln Asp Glu Lys 
            500                 505                 510         


Arg Tyr Leu Thr Gly Asn Glu Glu Ala Tyr Gly Arg Ser His Ile Pro 
        515                 520                 525             


Glu Gln Leu Met His Ile Tyr Ser Gln Pro Ile Ala Ile Leu Gln Thr 
    530                 535                 540                 


Ser Asp Leu Phe Ser Thr Pro Glu Gln Leu His Thr Ala Lys Ser Ala 
545                 550                 555                 560 


Thr Leu Pro Arg Lys Gly Gln Leu Val Tyr Gly Gln Leu Met Glu Pro 
                565                 570                 575     


Val Asn Arg Glu Asn Phe Thr Gln Thr Leu Pro Lys Met Pro Ile His 
            580                 585                 590         


Ser His Ala Gln Pro Pro Asp Ala Arg Glu Glu Asp Ile Ile Leu Glu 
        595                 600                 605             


Gly Gln Gln Ser Leu Pro Ser Gln Ala Ser Asp Trp Ser Arg Tyr Ser 
    610                 615                 620                 


Ser Ser Leu Leu Glu Ser Val Ser Val Pro Gly Thr Leu Asn Glu Ala 
625                 630                 635                 640 


Val Val Met Thr Pro Phe Ser Ser Glu Leu Gln Gly Ile Ser Glu Gln 
                645                 650                 655     


Thr Leu Leu Glu Leu Ser Lys Gly Lys Pro Ser Pro His Pro Arg Ala 
            660                 665                 670         


Trp Phe Val Ser Leu Asp Gly Lys Pro Val Ala Gln Val Arg His Ser 
        675                 680                 685             


Phe Ile Asp Leu Lys Lys Gly Lys Arg Thr Gln Ser Asn Asp Thr Ser 
    690                 695                 700                 


Leu Asp Ser Gly Val Asp Met Asn Glu Leu His Ser Ser Arg Lys Leu 
705                 710                 715                 720 


Glu Arg Glu Lys Thr Phe Ile Lys Ser Met His Gln Pro Lys Ile Leu 
                725                 730                 735     


Tyr Leu Glu Asp Leu Asp Leu Ser Ser Ser Glu Ser Gly Thr Thr Val 
            740                 745                 750         


Cys Ser Pro Glu Asp Pro Ala Leu Arg His Ile Leu Asp Gly Gly Ser 
        755                 760                 765             


Gly Val Ile Met Glu His Pro Gly Glu Glu Ser Pro Gly Arg Lys Ser 
    770                 775                 780                 


Thr Val Glu Asp Phe Glu Ala Asn Thr Ser Pro Thr Lys Arg Arg Gly 
785                 790                 795                 800 


Arg Pro Pro Leu Ala Lys Arg Asp Ser Lys Thr Asn Ile Trp Lys Lys 
                805                 810                 815     


Arg Glu Glu Arg Pro Leu Ile Pro Ile Asn 
            820                 825     


<210>  2997
<211>  2521
<212>  PRT
<213>  homo sapiens

<400>  2997

Met Glu Pro His Val Leu Gly Ala Val Leu Tyr Trp Leu Leu Leu Pro 
1               5                   10                  15      


Cys Ala Leu Leu Ala Ala Cys Leu Leu Arg Phe Ser Gly Leu Ser Leu 
            20                  25                  30          


Val Tyr Leu Leu Phe Leu Leu Leu Leu Pro Trp Phe Pro Gly Pro Thr 
        35                  40                  45              


Arg Cys Gly Leu Gln Gly His Thr Gly Arg Leu Leu Arg Ala Leu Leu 
    50                  55                  60                  


Gly Leu Ser Leu Leu Phe Leu Val Ala His Leu Ala Leu Gln Ile Cys 
65                  70                  75                  80  


Leu His Ile Val Pro Arg Leu Asp Gln Leu Leu Gly Pro Ser Cys Ser 
                85                  90                  95      


Arg Trp Glu Thr Leu Ser Arg His Ile Gly Val Thr Arg Leu Asp Leu 
            100                 105                 110         


Lys Asp Ile Pro Asn Ala Ile Arg Leu Val Ala Pro Asp Leu Gly Ile 
        115                 120                 125             


Leu Val Val Ser Ser Val Cys Leu Gly Ile Cys Gly Arg Leu Ala Arg 
    130                 135                 140                 


Asn Thr Arg Gln Ser Pro His Pro Arg Glu Leu Asp Asp Asp Glu Arg 
145                 150                 155                 160 


Asp Val Asp Ala Ser Pro Thr Ala Gly Leu Gln Glu Ala Ala Thr Leu 
                165                 170                 175     


Ala Pro Thr Arg Arg Ser Arg Leu Ala Ala Arg Phe Arg Val Thr Ala 
            180                 185                 190         


His Trp Leu Leu Val Ala Ala Gly Arg Val Leu Ala Val Thr Leu Leu 
        195                 200                 205             


Ala Leu Ala Gly Ile Ala His Pro Ser Ala Leu Ser Ser Val Tyr Leu 
    210                 215                 220                 


Leu Leu Phe Leu Ala Leu Cys Thr Trp Trp Ala Cys His Phe Pro Ile 
225                 230                 235                 240 


Ser Thr Arg Gly Phe Ser Arg Leu Cys Val Ala Val Gly Cys Phe Gly 
                245                 250                 255     


Ala Gly His Leu Ile Cys Leu Tyr Cys Tyr Gln Met Pro Leu Ala Gln 
            260                 265                 270         


Ala Leu Leu Pro Pro Ala Gly Ile Trp Ala Arg Val Leu Gly Leu Lys 
        275                 280                 285             


Asp Phe Val Gly Pro Thr Asn Cys Ser Ser Pro His Ala Leu Val Leu 
    290                 295                 300                 


Asn Thr Gly Leu Asp Trp Pro Val Tyr Ala Ser Pro Gly Val Leu Leu 
305                 310                 315                 320 


Leu Leu Cys Tyr Ala Thr Ala Ser Leu Arg Lys Leu Arg Ala Tyr Arg 
                325                 330                 335     


Pro Ser Gly Gln Arg Lys Glu Ala Ala Lys Gly Tyr Glu Ala Arg Glu 
            340                 345                 350         


Leu Glu Leu Ala Glu Leu Asp Gln Trp Pro Gln Glu Arg Glu Ser Asp 
        355                 360                 365             


Gln His Val Val Pro Thr Ala Pro Asp Thr Glu Ala Asp Asn Cys Ile 
    370                 375                 380                 


Val His Glu Leu Thr Gly Gln Ser Ser Val Leu Arg Arg Pro Val Arg 
385                 390                 395                 400 


Pro Lys Arg Ala Glu Pro Arg Glu Ala Ser Pro Leu His Ser Leu Gly 
                405                 410                 415     


His Leu Ile Met Asp Gln Ser Tyr Val Cys Ala Leu Ile Ala Met Met 
            420                 425                 430         


Val Trp Ser Ile Thr Tyr His Ser Trp Leu Thr Phe Val Leu Leu Leu 
        435                 440                 445             


Trp Ala Cys Leu Ile Trp Thr Val Arg Ser Arg His Gln Leu Ala Met 
    450                 455                 460                 


Leu Cys Ser Pro Cys Ile Leu Leu Tyr Gly Met Thr Leu Cys Cys Leu 
465                 470                 475                 480 


Arg Tyr Val Trp Ala Met Asp Leu Arg Pro Glu Leu Pro Thr Thr Leu 
                485                 490                 495     


Gly Pro Val Ser Leu Arg Gln Leu Gly Leu Glu His Thr Arg Tyr Pro 
            500                 505                 510         


Cys Leu Asp Leu Gly Ala Met Leu Leu Tyr Thr Leu Thr Phe Trp Leu 
        515                 520                 525             


Leu Leu Arg Gln Phe Val Lys Glu Lys Leu Leu Lys Trp Ala Glu Ser 
    530                 535                 540                 


Pro Ala Ala Leu Thr Glu Val Thr Val Ala Asp Thr Glu Pro Thr Arg 
545                 550                 555                 560 


Thr Gln Thr Leu Leu Gln Ser Leu Gly Glu Leu Val Lys Gly Val Tyr 
                565                 570                 575     


Ala Lys Tyr Trp Ile Tyr Val Cys Ala Gly Met Phe Ile Val Val Ser 
            580                 585                 590         


Phe Ala Gly Arg Leu Val Val Tyr Lys Ile Val Tyr Met Phe Leu Phe 
        595                 600                 605             


Leu Leu Cys Leu Thr Leu Phe Gln Val Tyr Tyr Ser Leu Trp Arg Lys 
    610                 615                 620                 


Leu Leu Lys Ala Phe Trp Trp Leu Val Val Ala Tyr Thr Met Leu Val 
625                 630                 635                 640 


Leu Ile Ala Val Tyr Thr Phe Gln Phe Gln Asp Phe Pro Ala Tyr Trp 
                645                 650                 655     


Arg Asn Leu Thr Gly Phe Thr Asp Glu Gln Leu Gly Asp Leu Gly Leu 
            660                 665                 670         


Glu Gln Phe Ser Val Ser Glu Leu Phe Ser Ser Ile Leu Val Pro Gly 
        675                 680                 685             


Phe Phe Leu Leu Ala Cys Ile Leu Gln Leu His Tyr Phe His Arg Pro 
    690                 695                 700                 


Phe Met Gln Leu Thr Asp Met Glu His Val Ser Leu Pro Gly Thr Arg 
705                 710                 715                 720 


Leu Pro Arg Trp Ala His Arg Gln Asp Ala Val Ser Gly Thr Pro Leu 
                725                 730                 735     


Leu Arg Glu Glu Gln Gln Glu His Gln Gln Gln Gln Gln Glu Glu Glu 
            740                 745                 750         


Glu Glu Glu Glu Asp Ser Arg Asp Glu Gly Leu Gly Val Ala Thr Pro 
        755                 760                 765             


His Gln Ala Thr Gln Val Pro Glu Gly Ala Ala Lys Trp Gly Leu Val 
    770                 775                 780                 


Ala Glu Arg Leu Leu Glu Leu Ala Ala Gly Phe Ser Asp Val Leu Ser 
785                 790                 795                 800 


Arg Val Gln Val Phe Leu Arg Arg Leu Leu Glu Leu His Val Phe Lys 
                805                 810                 815     


Leu Val Ala Leu Tyr Thr Val Trp Val Ala Leu Lys Glu Val Ser Val 
            820                 825                 830         


Met Asn Leu Leu Leu Val Val Leu Trp Ala Phe Ala Leu Pro Tyr Pro 
        835                 840                 845             


Arg Phe Arg Pro Met Ala Ser Cys Leu Ser Thr Val Trp Thr Cys Val 
    850                 855                 860                 


Ile Ile Val Cys Lys Met Leu Tyr Gln Leu Lys Val Val Asn Pro Gln 
865                 870                 875                 880 


Glu Tyr Ser Ser Asn Cys Thr Glu Pro Phe Pro Asn Ser Thr Asn Leu 
                885                 890                 895     


Leu Pro Thr Glu Ile Ser Gln Ser Leu Leu Tyr Arg Gly Pro Val Asp 
            900                 905                 910         


Pro Ala Asn Trp Phe Gly Val Arg Lys Gly Phe Pro Asn Leu Gly Tyr 
        915                 920                 925             


Ile Gln Asn His Leu Gln Val Leu Leu Leu Leu Val Phe Glu Ala Ile 
    930                 935                 940                 


Val Tyr Arg Arg Gln Glu His Tyr Arg Arg Gln His Gln Leu Ala Pro 
945                 950                 955                 960 


Leu Pro Ala Gln Ala Val Phe Ala Ser Gly Thr Arg Gln Gln Leu Asp 
                965                 970                 975     


Gln Asp Leu Leu Gly Cys Leu Lys Tyr Phe Ile Asn Phe Phe Phe Tyr 
            980                 985                 990         


Lys Phe Gly Leu Glu Ile Cys Phe  Leu Met Ala Val Asn  Val Ile Gly 
        995                 1000                 1005             


Gln Arg  Met Asn Phe Leu Val  Thr Leu His Gly Cys  Trp Leu Val 
    1010                 1015                 1020             


Ala Ile  Leu Thr Arg Arg His  Arg Gln Ala Ile Ala  Arg Leu Trp 
    1025                 1030                 1035             


Pro Asn  Tyr Cys Leu Phe Leu  Ala Leu Phe Leu Leu  Tyr Gln Tyr 
    1040                 1045                 1050             


Leu Leu  Cys Leu Gly Met Pro  Pro Ala Leu Cys Ile  Asp Tyr Pro 
    1055                 1060                 1065             


Trp Arg  Trp Ser Arg Ala Val  Pro Met Asn Ser Ala  Leu Ile Lys 
    1070                 1075                 1080             


Trp Leu  Tyr Leu Pro Asp Phe  Phe Arg Ala Pro Asn  Ser Thr Asn 
    1085                 1090                 1095             


Leu Ile  Ser Asp Phe Leu Leu  Leu Leu Cys Ala Ser  Gln Gln Trp 
    1100                 1105                 1110             


Gln Val  Phe Ser Ala Glu Arg  Thr Glu Glu Trp Gln  Arg Met Ala 
    1115                 1120                 1125             


Gly Val  Asn Thr Asp Arg Leu  Glu Pro Leu Arg Gly  Glu Pro Asn 
    1130                 1135                 1140             


Pro Val  Pro Asn Phe Ile His  Cys Arg Ser Tyr Leu  Asp Met Leu 
    1145                 1150                 1155             


Lys Val  Ala Val Phe Arg Tyr  Leu Phe Trp Leu Val  Leu Val Val 
    1160                 1165                 1170             


Val Phe  Val Thr Gly Ala Thr  Arg Ile Ser Ile Phe  Gly Leu Gly 
    1175                 1180                 1185             


Tyr Leu  Leu Ala Cys Phe Tyr  Leu Leu Leu Phe Gly  Thr Ala Leu 
    1190                 1195                 1200             


Leu Gln  Arg Asp Thr Arg Ala  Arg Leu Val Leu Trp  Asp Cys Leu 
    1205                 1210                 1215             


Ile Leu  Tyr Asn Val Thr Val  Ile Ile Ser Lys Asn  Met Leu Ser 
    1220                 1225                 1230             


Leu Leu  Ala Cys Val Phe Val  Glu Gln Met Gln Thr  Gly Phe Cys 
    1235                 1240                 1245             


Trp Val  Ile Gln Leu Phe Ser  Leu Val Cys Thr Val  Lys Gly Tyr 
    1250                 1255                 1260             


Tyr Asp  Pro Lys Glu Met Met  Asp Arg Asp Gln Asp  Cys Leu Leu 
    1265                 1270                 1275             


Pro Val  Glu Glu Ala Gly Ile  Ile Trp Asp Ser Val  Cys Phe Phe 
    1280                 1285                 1290             


Phe Leu  Leu Leu Gln Arg Arg  Val Phe Leu Ser His  Tyr Tyr Leu 
    1295                 1300                 1305             


His Val  Arg Ala Asp Leu Gln  Ala Thr Ala Leu Leu  Ala Ser Arg 
    1310                 1315                 1320             


Gly Phe  Ala Leu Tyr Asn Ala  Ala Asn Leu Lys Ser  Ile Asp Phe 
    1325                 1330                 1335             


His Arg  Arg Ile Glu Glu Lys  Ser Leu Ala Gln Leu  Lys Arg Gln 
    1340                 1345                 1350             


Met Glu  Arg Ile Arg Ala Lys  Gln Glu Lys His Arg  Gln Gly Arg 
    1355                 1360                 1365             


Val Asp  Arg Ser Arg Pro Gln  Asp Thr Leu Gly Pro  Lys Asp Pro 
    1370                 1375                 1380             


Gly Leu  Glu Pro Gly Pro Asp  Ser Pro Gly Gly Ser  Ser Pro Pro 
    1385                 1390                 1395             


Arg Arg  Gln Trp Trp Arg Pro  Trp Leu Asp His Ala  Thr Val Ile 
    1400                 1405                 1410             


His Ser  Gly Asp Tyr Phe Leu  Phe Glu Ser Asp Ser  Glu Glu Glu 
    1415                 1420                 1425             


Glu Glu  Ala Val Pro Glu Asp  Pro Arg Pro Ser Ala  Gln Ser Ala 
    1430                 1435                 1440             


Phe Gln  Leu Ala Tyr Gln Ala  Trp Val Thr Asn Ala  Gln Ala Val 
    1445                 1450                 1455             


Leu Arg  Arg Arg Gln Gln Glu  Gln Glu Gln Ala Arg  Gln Glu Gln 
    1460                 1465                 1470             


Ala Gly  Gln Leu Pro Thr Gly  Gly Gly Pro Ser Gln  Glu Val Glu 
    1475                 1480                 1485             


Pro Ala  Glu Gly Pro Glu Glu  Ala Ala Ala Gly Arg  Ser His Val 
    1490                 1495                 1500             


Val Gln  Arg Val Leu Ser Thr  Ala Gln Phe Leu Trp  Met Leu Gly 
    1505                 1510                 1515             


Gln Ala  Leu Val Asp Glu Leu  Thr Arg Trp Leu Gln  Glu Phe Thr 
    1520                 1525                 1530             


Arg His  His Gly Thr Met Ser  Asp Val Leu Arg Ala  Glu Arg Tyr 
    1535                 1540                 1545             


Leu Leu  Thr Gln Glu Leu Leu  Gln Gly Gly Glu Val  His Arg Gly 
    1550                 1555                 1560             


Val Leu  Asp Gln Leu Tyr Thr  Ser Gln Ala Glu Ala  Thr Leu Pro 
    1565                 1570                 1575             


Gly Pro  Thr Glu Ala Pro Asn  Ala Pro Ser Thr Val  Ser Ser Gly 
    1580                 1585                 1590             


Leu Gly  Ala Glu Glu Pro Leu  Ser Ser Met Thr Asp  Asp Met Gly 
    1595                 1600                 1605             


Ser Pro  Leu Ser Thr Gly Tyr  His Thr Arg Ser Gly  Ser Glu Glu 
    1610                 1615                 1620             


Ala Val  Thr Asp Pro Gly Glu  Arg Glu Ala Gly Ala  Ser Leu Tyr 
    1625                 1630                 1635             


Gln Gly  Leu Met Arg Thr Ala  Ser Glu Leu Leu Leu  Asp Arg Arg 
    1640                 1645                 1650             


Leu Arg  Ile Pro Glu Leu Glu  Glu Ala Glu Leu Phe  Ala Glu Gly 
    1655                 1660                 1665             


Gln Gly  Arg Ala Leu Arg Leu  Leu Arg Ala Val Tyr  Gln Cys Val 
    1670                 1675                 1680             


Ala Ala  His Ser Glu Leu Leu  Cys Tyr Phe Ile Ile  Ile Leu Asn 
    1685                 1690                 1695             


His Met  Val Thr Ala Ser Ala  Gly Ser Leu Val Leu  Pro Val Leu 
    1700                 1705                 1710             


Val Phe  Leu Trp Ala Met Leu  Ser Ile Pro Arg Pro  Ser Lys Arg 
    1715                 1720                 1725             


Phe Trp  Met Thr Ala Ile Val  Phe Thr Glu Ile Ala  Val Val Val 
    1730                 1735                 1740             


Lys Tyr  Leu Phe Gln Phe Gly  Phe Phe Pro Trp Asn  Ser His Val 
    1745                 1750                 1755             


Val Leu  Arg Arg Tyr Glu Asn  Lys Pro Tyr Phe Pro  Pro Arg Ile 
    1760                 1765                 1770             


Leu Gly  Leu Glu Lys Thr Asp  Gly Tyr Ile Lys Tyr  Asp Leu Val 
    1775                 1780                 1785             


Gln Leu  Met Ala Leu Phe Phe  His Arg Ser Gln Leu  Leu Cys Tyr 
    1790                 1795                 1800             


Gly Leu  Trp Asp His Glu Glu  Asp Ser Pro Ser Lys  Glu His Asp 
    1805                 1810                 1815             


Lys Ser  Gly Glu Glu Glu Gln  Gly Ala Glu Glu Gly  Pro Gly Val 
    1820                 1825                 1830             


Pro Ala  Ala Thr Thr Glu Asp  His Ile Gln Val Glu  Ala Arg Val 
    1835                 1840                 1845             


Gly Pro  Thr Asp Gly Thr Pro  Glu Pro Gln Val Glu  Leu Arg Pro 
    1850                 1855                 1860             


Arg Asp  Thr Arg Arg Ile Ser  Leu Arg Phe Arg Arg  Arg Lys Lys 
    1865                 1870                 1875             


Glu Gly  Pro Ala Arg Lys Gly  Ala Ala Ala Ile Glu  Ala Glu Asp 
    1880                 1885                 1890             


Arg Glu  Glu Glu Glu Gly Glu  Glu Glu Lys Glu Ala  Pro Thr Gly 
    1895                 1900                 1905             


Arg Glu  Lys Arg Pro Ser Arg  Ser Gly Gly Arg Val  Arg Ala Ala 
    1910                 1915                 1920             


Gly Arg  Arg Leu Gln Gly Phe  Cys Leu Ser Leu Ala  Gln Gly Thr 
    1925                 1930                 1935             


Tyr Arg  Pro Leu Arg Arg Phe  Phe His Asp Ile Leu  His Thr Lys 
    1940                 1945                 1950             


Tyr Arg  Ala Ala Thr Asp Val  Tyr Ala Leu Met Phe  Leu Ala Asp 
    1955                 1960                 1965             


Val Val  Asp Phe Ile Ile Ile  Ile Phe Gly Phe Trp  Ala Phe Gly 
    1970                 1975                 1980             


Lys His  Ser Ala Ala Thr Asp  Ile Thr Ser Ser Leu  Ser Asp Asp 
    1985                 1990                 1995             


Gln Val  Pro Glu Ala Phe Leu  Val Met Leu Leu Ile  Gln Phe Ser 
    2000                 2005                 2010             


Thr Met  Val Val Asp Arg Ala  Leu Tyr Leu Arg Lys  Thr Val Leu 
    2015                 2020                 2025             


Gly Lys  Leu Ala Phe Gln Val  Ala Leu Val Leu Ala  Ile His Leu 
    2030                 2035                 2040             


Trp Met  Phe Phe Ile Leu Pro  Ala Val Thr Glu Arg  Met Phe Asn 
    2045                 2050                 2055             


Gln Asn  Val Val Ala Gln Leu  Trp Tyr Phe Val Lys  Cys Ile Tyr 
    2060                 2065                 2070             


Phe Ala  Leu Ser Ala Tyr Gln  Ile Arg Cys Gly Tyr  Pro Thr Arg 
    2075                 2080                 2085             


Ile Leu  Gly Asn Phe Leu Thr  Lys Lys Tyr Asn His  Leu Asn Leu 
    2090                 2095                 2100             


Phe Leu  Phe Gln Gly Phe Arg  Leu Val Pro Phe Leu  Val Glu Leu 
    2105                 2110                 2115             


Arg Ala  Val Met Asp Trp Val  Trp Thr Asp Thr Thr  Leu Ser Leu 
    2120                 2125                 2130             


Ser Ser  Trp Met Cys Val Glu  Asp Ile Tyr Ala Asn  Ile Phe Ile 
    2135                 2140                 2145             


Ile Lys  Cys Ser Arg Glu Thr  Glu Lys Lys Tyr Pro  Gln Pro Lys 
    2150                 2155                 2160             


Gly Gln  Lys Lys Lys Lys Ile  Val Lys Tyr Gly Met  Gly Gly Leu 
    2165                 2170                 2175             


Ile Ile  Leu Phe Leu Ile Ala  Ile Ile Trp Phe Pro  Leu Leu Phe 
    2180                 2185                 2190             


Met Ser  Leu Val Arg Ser Val  Val Gly Val Val Asn  Gln Pro Ile 
    2195                 2200                 2205             


Asp Val  Thr Val Thr Leu Lys  Leu Gly Gly Tyr Glu  Pro Leu Phe 
    2210                 2215                 2220             


Thr Met  Ser Ala Gln Gln Pro  Ser Ile Ile Pro Phe  Thr Ala Gln 
    2225                 2230                 2235             


Ala Tyr  Glu Glu Leu Ser Arg  Gln Phe Asp Pro Gln  Pro Leu Ala 
    2240                 2245                 2250             


Met Gln  Phe Ile Ser Gln Tyr  Ser Pro Glu Asp Ile  Val Thr Ala 
    2255                 2260                 2265             


Gln Ile  Glu Gly Ser Ser Gly  Ala Leu Trp Arg Ile  Ser Pro Pro 
    2270                 2275                 2280             


Ser Arg  Ala Gln Met Lys Arg  Glu Leu Tyr Asn Gly  Thr Ala Asp 
    2285                 2290                 2295             


Ile Thr  Leu Arg Phe Thr Trp  Asn Phe Gln Arg Asp  Leu Ala Lys 
    2300                 2305                 2310             


Gly Gly  Thr Val Glu Tyr Ala  Asn Glu Lys His Met  Leu Ala Leu 
    2315                 2320                 2325             


Ala Pro  Asn Ser Thr Ala Arg  Arg Gln Leu Ala Ser  Leu Leu Glu 
    2330                 2335                 2340             


Gly Thr  Ser Asp Gln Ser Val  Val Ile Pro Asn Leu  Phe Pro Lys 
    2345                 2350                 2355             


Tyr Ile  Arg Ala Pro Asn Gly  Pro Glu Ala Asn Pro  Val Lys Gln 
    2360                 2365                 2370             


Leu Gln  Pro Asn Glu Glu Ala  Asp Tyr Leu Gly Val  Arg Ile Gln 
    2375                 2380                 2385             


Leu Arg  Arg Glu Gln Gly Ala  Gly Ala Thr Gly Phe  Leu Glu Trp 
    2390                 2395                 2400             


Trp Val  Ile Glu Leu Gln Glu  Cys Arg Thr Asp Cys  Asn Leu Leu 
    2405                 2410                 2415             


Pro Met  Val Ile Phe Ser Asp  Lys Val Ser Pro Pro  Ser Leu Gly 
    2420                 2425                 2430             


Phe Leu  Ala Gly Tyr Gly Ile  Met Gly Leu Tyr Val  Ser Ile Val 
    2435                 2440                 2445             


Leu Val  Ile Gly Lys Phe Val  Arg Gly Phe Phe Ser  Glu Ile Ser 
    2450                 2455                 2460             


His Ser  Ile Met Phe Glu Glu  Leu Pro Cys Val Asp  Arg Ile Leu 
    2465                 2470                 2475             


Lys Leu  Cys Gln Asp Ile Phe  Leu Val Arg Glu Thr  Arg Glu Leu 
    2480                 2485                 2490             


Glu Leu  Glu Glu Glu Leu Tyr  Ala Lys Leu Ile Phe  Leu Tyr Arg 
    2495                 2500                 2505             


Ser Pro  Glu Thr Met Ile Lys  Trp Thr Arg Glu Lys  Glu 
    2510                 2515                 2520     


<210>  2998
<211>  238
<212>  PRT
<213>  homo sapiens

<400>  2998

Met Ala Ser Arg Trp Gln Asn Met Gly Thr Ser Val Arg Arg Arg Ser 
1               5                   10                  15      


Leu Gln His Gln Glu Gln Leu Glu Asp Ser Lys Glu Leu Gln Pro Val 
            20                  25                  30          


Val Ser His Gln Glu Thr Ser Val Gly Ala Leu Gly Ser Leu Cys Arg 
        35                  40                  45              


Gln Phe Gln Arg Arg Leu Pro Leu Arg Ala Val Asn Leu Asn Leu Arg 
    50                  55                  60                  


Ala Gly Pro Ser Trp Lys Arg Leu Glu Thr Pro Glu Pro Gly Gln Gln 
65                  70                  75                  80  


Gly Leu Gln Ala Ala Ala Arg Ser Ala Lys Ser Ala Leu Gly Ala Val 
                85                  90                  95      


Ser Gln Arg Ile Gln Glu Ser Cys Gln Ser Gly Thr Lys Trp Leu Val 
            100                 105                 110         


Glu Thr Gln Val Lys Ala Arg Arg Arg Lys Arg Gly Ala Gln Lys Gly 
        115                 120                 125             


Ser Gly Ser Pro Thr His Ser Leu Ser Gln Lys Ser Thr Arg Leu Ser 
    130                 135                 140                 


Gly Ala Ala Pro Ala His Ser Ala Ala Asp Pro Trp Glu Lys Glu His 
145                 150                 155                 160 


His Arg Leu Ser Val Arg Met Gly Ser His Ala His Pro Leu Arg Arg 
                165                 170                 175     


Ser Arg Arg Glu Ala Ala Phe Arg Ser Pro Tyr Ser Ser Thr Glu Pro 
            180                 185                 190         


Leu Cys Ser Pro Ser Glu Ser Asp Ser Asp Leu Glu Pro Val Gly Ala 
        195                 200                 205             


Gly Ile Gln His Leu Gln Lys Leu Ser Gln Glu Leu Asp Glu Ala Ile 
    210                 215                 220                 


Met Ala Glu Glu Ser Gly Asp Ile Val Ser Leu Ile His Asp 
225                 230                 235             


<210>  2999
<211>  1460
<212>  PRT
<213>  homo sapiens

<400>  2999

Met Ser Leu Thr Ser Trp Phe Leu Val Ser Ser Gly Gly Thr Arg His 
1               5                   10                  15      


Arg Leu Pro Arg Glu Met Ile Phe Val Gly Arg Asp Asp Cys Glu Leu 
            20                  25                  30          


Met Leu Gln Ser Arg Ser Val Asp Lys Gln His Ala Val Ile Asn Tyr 
        35                  40                  45              


Asp Ala Ser Thr Asp Glu His Leu Val Lys Asp Leu Gly Ser Leu Asn 
    50                  55                  60                  


Gly Thr Phe Val Asn Asp Val Arg Ile Pro Glu Gln Thr Tyr Ile Thr 
65                  70                  75                  80  


Leu Lys Leu Glu Asp Lys Leu Arg Phe Gly Tyr Asp Thr Asn Leu Phe 
                85                  90                  95      


Thr Val Val Gln Gly Glu Met Arg Val Pro Glu Glu Ala Leu Lys His 
            100                 105                 110         


Glu Lys Phe Thr Ile Gln Leu Gln Leu Ser Gln Lys Ser Ser Glu Ser 
        115                 120                 125             


Glu Leu Ser Lys Ser Ala Ser Ala Lys Ser Ile Asp Ser Lys Val Ala 
    130                 135                 140                 


Asp Ala Ala Thr Glu Val Gln His Lys Thr Thr Glu Ala Leu Lys Ser 
145                 150                 155                 160 


Glu Glu Lys Ala Met Asp Ile Ser Ala Met Pro Arg Gly Thr Pro Leu 
                165                 170                 175     


Tyr Gly Gln Pro Ser Trp Trp Gly Asp Asp Glu Val Asp Glu Lys Arg 
            180                 185                 190         


Ala Phe Lys Thr Asn Gly Lys Pro Glu Glu Lys Asn His Glu Ala Gly 
        195                 200                 205             


Thr Ser Gly Cys Gly Ile Asp Ala Lys Gln Val Glu Glu Gln Ser Ala 
    210                 215                 220                 


Ala Ala Asn Glu Glu Val Leu Phe Pro Phe Cys Arg Glu Pro Ser Tyr 
225                 230                 235                 240 


Phe Glu Ile Pro Thr Lys Glu Phe Gln Gln Pro Ser Gln Ile Thr Glu 
                245                 250                 255     


Ser Thr Ile His Glu Ile Pro Thr Lys Asp Thr Pro Ser Ser His Ile 
            260                 265                 270         


Thr Gly Ala Gly His Ala Ser Phe Thr Ile Glu Phe Asp Asp Ser Thr 
        275                 280                 285             


Pro Gly Lys Val Thr Ile Arg Asp His Val Thr Lys Phe Thr Ser Asp 
    290                 295                 300                 


Gln Arg His Lys Ser Lys Lys Ser Ser Pro Gly Thr Gln Asp Leu Leu 
305                 310                 315                 320 


Gly Ile Gln Thr Gly Met Met Ala Pro Glu Asn Lys Val Ala Asp Trp 
                325                 330                 335     


Leu Ala Gln Asn Asn Pro Pro Gln Met Leu Trp Glu Arg Thr Glu Glu 
            340                 345                 350         


Asp Ser Lys Ser Ile Lys Ser Asp Val Pro Val Tyr Leu Lys Arg Leu 
        355                 360                 365             


Lys Gly Asn Lys His Asp Asp Gly Thr Gln Ser Asp Ser Glu Asn Ala 
    370                 375                 380                 


Gly Ala His Arg Arg Cys Ser Lys Arg Ala Thr Leu Glu Glu His Leu 
385                 390                 395                 400 


Arg Arg His His Ser Glu His Lys Lys Leu Gln Lys Val Gln Ala Thr 
                405                 410                 415     


Glu Lys His Gln Asp Gln Ala Val Val Phe Gly Val Asp Asp Asn Gln 
            420                 425                 430         


Asp Tyr Asn Arg Pro Val Ile Asn Glu Lys His Lys Asp Leu Ile Lys 
        435                 440                 445             


Asp Trp Ala Leu Ser Ser Ala Ala Ala Val Met Glu Glu Arg Lys Pro 
    450                 455                 460                 


Leu Thr Thr Ser Gly Phe His His Ser Glu Glu Gly Thr Ser Ser Ser 
465                 470                 475                 480 


Gly Ser Lys Arg Trp Val Ser Gln Trp Ala Ser Leu Ala Ala Asn His 
                485                 490                 495     


Thr Arg His Asp Gln Glu Glu Arg Ile Met Glu Phe Ser Ala Pro Leu 
            500                 505                 510         


Pro Leu Glu Asn Glu Thr Glu Ile Ser Glu Ser Gly Met Thr Val Arg 
        515                 520                 525             


Ser Thr Gly Ser Ala Thr Ser Leu Ala Ser Gln Gly Glu Arg Arg Arg 
    530                 535                 540                 


Arg Thr Leu Pro Gln Leu Pro Asn Glu Glu Lys Ser Leu Glu Ser His 
545                 550                 555                 560 


Arg Ala Lys Val Val Thr Gln Arg Ser Glu Ile Gly Glu Lys Gln Asp 
                565                 570                 575     


Thr Glu Leu Gln Glu Lys Glu Thr Pro Thr Gln Val Tyr Gln Lys Asp 
            580                 585                 590         


Lys Gln Asp Ala Asp Arg Pro Leu Ser Lys Met Asn Arg Ala Val Asn 
        595                 600                 605             


Gly Glu Thr Leu Lys Thr Gly Gly Asp Asn Lys Thr Leu Leu His Leu 
    610                 615                 620                 


Gly Ser Ser Ala Pro Gly Lys Glu Lys Ser Glu Thr Asp Lys Glu Thr 
625                 630                 635                 640 


Ser Leu Val Lys Gln Thr Leu Ala Lys Leu Gln Gln Gln Glu Gln Arg 
                645                 650                 655     


Glu Glu Ala Gln Trp Thr Pro Thr Lys Leu Ser Ser Lys Asn Val Ser 
            660                 665                 670         


Gly Gln Thr Asp Lys Cys Arg Glu Glu Thr Phe Lys Gln Glu Ser Gln 
        675                 680                 685             


Pro Pro Glu Lys Asn Ser Gly His Ser Thr Ser Lys Gly Asp Arg Val 
    690                 695                 700                 


Ala Gln Ser Glu Ser Lys Arg Arg Lys Ala Glu Glu Ile Leu Lys Ser 
705                 710                 715                 720 


Gln Thr Pro Lys Gly Gly Asp Lys Lys Glu Ser Ser Lys Ser Leu Val 
                725                 730                 735     


Arg Gln Gly Ser Phe Thr Ile Glu Lys Pro Ser Pro Asn Ile Pro Ile 
            740                 745                 750         


Glu Leu Ile Pro His Ile Asn Lys Gln Thr Ser Ser Thr Pro Ser Ser 
        755                 760                 765             


Leu Ala Leu Thr Ser Ala Ser Arg Ile Arg Glu Arg Ser Glu Ser Leu 
    770                 775                 780                 


Asp Pro Asp Ser Ser Met Asp Thr Thr Leu Ile Leu Lys Asp Thr Glu 
785                 790                 795                 800 


Ala Val Met Ala Phe Leu Glu Ala Lys Leu Arg Glu Asp Asn Lys Thr 
                805                 810                 815     


Asp Glu Gly Pro Asp Thr Pro Ser Tyr Asn Arg Asp Asn Ser Ile Ser 
            820                 825                 830         


Pro Glu Ser Asp Val Asp Thr Ala Ser Thr Ile Ser Leu Val Thr Gly 
        835                 840                 845             


Glu Thr Glu Arg Lys Ser Thr Gln Lys Arg Lys Ser Phe Thr Ser Leu 
    850                 855                 860                 


Tyr Lys Asp Arg Cys Ser Thr Gly Ser Pro Ser Lys Asp Val Thr Lys 
865                 870                 875                 880 


Ser Ser Ser Ser Gly Ala Arg Glu Lys Met Glu Lys Lys Thr Lys Ser 
                885                 890                 895     


Arg Ser Thr Asp Val Gly Ser Arg Ala Asp Gly Arg Lys Phe Val Gln 
            900                 905                 910         


Ser Ser Gly Arg Ile Arg Gln Pro Ser Val Asp Leu Thr Asp Asp Asp 
        915                 920                 925             


Gln Thr Ser Ser Val Pro His Ser Ala Ile Ser Asp Ile Met Ser Ser 
    930                 935                 940                 


Asp Gln Glu Thr Tyr Ser Cys Lys Pro His Gly Arg Thr Pro Leu Thr 
945                 950                 955                 960 


Ser Ala Asp Glu His Val His Ser Lys Leu Glu Gly Ser Lys Val Thr 
                965                 970                 975     


Lys Ser Lys Thr Ser Pro Val Val Ser Gly Ser Ser Ser Lys Ser Thr 
            980                 985                 990         


Thr Leu Pro Arg Pro Arg Pro Thr  Arg Thr Ser Leu Leu  Arg Arg Ala 
        995                 1000                 1005             


Arg Leu  Gly Glu Ala Ser Asp  Ser Glu Leu Ala Asp  Ala Asp Lys 
    1010                 1015                 1020             


Ala Ser  Val Ala Ser Glu Val  Ser Thr Thr Ser Ser  Thr Ser Lys 
    1025                 1030                 1035             


Pro Pro  Thr Gly Arg Arg Asn  Ile Ser Arg Ile Asp  Leu Leu Ala 
    1040                 1045                 1050             


Gln Pro  Arg Arg Thr Arg Leu  Gly Ser Leu Ser Ala  Arg Ser Asp 
    1055                 1060                 1065             


Ser Glu  Ala Thr Ile Ser Arg  Ser Ser Ala Ser Ser  Arg Thr Ala 
    1070                 1075                 1080             


Glu Ala  Ile Ile Arg Ser Gly  Ala Arg Leu Val Pro  Ser Asp Lys 
    1085                 1090                 1095             


Phe Ser  Pro Arg Ile Arg Ala  Asn Ser Ile Ser Arg  Leu Ser Asp 
    1100                 1105                 1110             


Ser Lys  Val Lys Ser Met Thr  Ser Ala His Gly Ser  Ala Ser Ala 
    1115                 1120                 1125             


Leu Lys  Thr Thr Arg Leu Gln  Ser Ala Gly Ser Ala  Met Pro Thr 
    1130                 1135                 1140             


Ser Ser  Ser Phe Lys His Arg  Ile Lys Glu Gln Glu  Asp Tyr Ile 
    1145                 1150                 1155             


Arg Asp  Trp Thr Ala His Arg  Glu Glu Ile Ala Arg  Ile Ser Gln 
    1160                 1165                 1170             


Asp Leu  Ala Leu Ile Ala Arg  Glu Ile Asn Asp Val  Ala Gly Glu 
    1175                 1180                 1185             


Ile Asp  Ser Val Thr Ser Ser  Gly Thr Ala Pro Ser  Thr Thr Val 
    1190                 1195                 1200             


Ser Thr  Ala Ala Thr Thr Pro  Gly Ser Ala Ile Asp  Thr Arg Glu 
    1205                 1210                 1215             


Glu Val  Gly Asp Leu His Gly  Glu Met His Lys Leu  Val Asp Arg 
    1220                 1225                 1230             


Val Phe  Asp Glu Ser Leu Asn  Phe Arg Lys Ile Pro  Pro Leu Val 
    1235                 1240                 1245             


His Ser  Lys Thr Pro Glu Gly  Asn Asn Gly Arg Ser  Gly Asp Pro 
    1250                 1255                 1260             


Arg Pro  Gln Ala Ala Glu Pro  Pro Asp His Leu Thr  Ile Thr Arg 
    1265                 1270                 1275             


Arg Arg  Thr Trp Ser Arg Asp  Glu Val Met Gly Asp  Asn Leu Leu 
    1280                 1285                 1290             


Leu Ser  Ser Val Phe Gln Phe  Ser Lys Lys Ile Arg  Gln Ser Ile 
    1295                 1300                 1305             


Asp Lys  Thr Ala Gly Lys Ile  Arg Ile Leu Phe Lys  Asp Lys Asp 
    1310                 1315                 1320             


Arg Asn  Trp Asp Asp Ile Glu  Ser Lys Leu Arg Ala  Glu Ser Glu 
    1325                 1330                 1335             


Val Pro  Ile Val Lys Thr Ser  Ser Met Glu Ile Ser  Ser Ile Leu 
    1340                 1345                 1350             


Gln Glu  Leu Lys Arg Val Glu  Lys Gln Leu Gln Ala  Ile Asn Ala 
    1355                 1360                 1365             


Met Ile  Asp Pro Asp Gly Thr  Leu Glu Ala Leu Asn  Asn Met Gly 
    1370                 1375                 1380             


Phe Pro  Ser Ala Met Leu Pro  Ser Pro Pro Lys Gln  Lys Ser Ser 
    1385                 1390                 1395             


Pro Val  Asn Asn His His Ser  Pro Gly Gln Thr Pro  Thr Leu Gly 
    1400                 1405                 1410             


Gln Pro  Glu Ala Arg Ala Leu  His Pro Ala Ala Val  Ser Ala Ala 
    1415                 1420                 1425             


Ala Glu  Phe Glu Asn Ala Glu  Ser Glu Ala Asp Phe  Ser Ile His 
    1430                 1435                 1440             


Phe Asn  Arg Phe Asn Pro Asp  Gly Glu Glu Glu Asp  Val Thr Val 
    1445                 1450                 1455             


Gln Glu  
    1460 


<210>  3000
<211>  1151
<212>  PRT
<213>  homo sapiens

<400>  3000

Met Ser Ser Glu Cys Asp Gly Gly Ser Lys Ala Val Met Asn Gly Leu 
1               5                   10                  15      


Ala Pro Gly Ser Asn Gly Gln Asp Lys Ala Thr Ala Asp Pro Leu Arg 
            20                  25                  30          


Ala Arg Ser Ile Ser Ala Val Lys Ile Ile Pro Val Lys Thr Val Lys 
        35                  40                  45              


Asn Ala Ser Gly Leu Val Leu Pro Thr Asp Met Asp Pro Thr Lys Ile 
    50                  55                  60                  


Cys Thr Gly Lys Gly Ala Val Thr Leu Arg Ala Ser Ser Ser Tyr Arg 
65                  70                  75                  80  


Glu Thr Pro Ser Ser Ser Pro Ala Ser Pro Gln Glu Thr Arg Gln His 
                85                  90                  95      


Glu Ser Lys Pro Gly Leu Glu Pro Glu Pro Ser Ser Ala Asp Glu Trp 
            100                 105                 110         


Arg Leu Ser Ser Ser Ala Asp Ala Asn Gly Asn Ala Gln Pro Ser Ser 
        115                 120                 125             


Leu Ala Ala Lys Gly Tyr Arg Ser Val His Pro Asn Leu Pro Ser Asp 
    130                 135                 140                 


Lys Ser Gln Asp Ala Thr Ser Ser Ser Ala Ala Gln Pro Glu Val Ile 
145                 150                 155                 160 


Val Val Pro Leu Tyr Leu Val Asn Thr Asp Arg Gly Gln Glu Gly Thr 
                165                 170                 175     


Ala Arg Pro Pro Thr Pro Leu Gly Pro Leu Gly Cys Val Pro Thr Ile 
            180                 185                 190         


Pro Ala Thr Ala Ser Ala Ala Ser Pro Leu Thr Phe Pro Thr Leu Asp 
        195                 200                 205             


Asp Phe Ile Pro Pro His Leu Gln Arg Trp Pro His His Ser Gln Pro 
    210                 215                 220                 


Ala Arg Ala Ser Gly Ser Phe Ala Pro Ile Ser Gln Thr Pro Pro Ser 
225                 230                 235                 240 


Phe Ser Pro Pro Pro Pro Leu Val Pro Pro Ala Pro Glu Asp Leu Arg 
                245                 250                 255     


Arg Val Ser Glu Pro Asp Leu Thr Gly Ala Val Ser Ser Thr Asp Ser 
            260                 265                 270         


Ser Pro Leu Leu Asn Glu Val Ser Ser Ser Leu Ile Gly Thr Asp Ser 
        275                 280                 285             


Gln Ala Phe Pro Ser Val Ser Lys Pro Ser Ser Ala Tyr Pro Ser Thr 
    290                 295                 300                 


Thr Ile Val Asn Pro Thr Ile Val Leu Leu Gln His Asn Arg Glu Gln 
305                 310                 315                 320 


Gln Lys Arg Leu Ser Ser Leu Ser Asp Pro Val Ser Glu Arg Arg Val 
                325                 330                 335     


Gly Glu Gln Asp Ser Ala Pro Thr Gln Glu Lys Pro Thr Ser Pro Gly 
            340                 345                 350         


Lys Ala Ile Glu Lys Arg Ala Lys Asp Asp Ser Arg Arg Val Val Lys 
        355                 360                 365             


Ser Thr Gln Asp Leu Ser Asp Val Ser Met Asp Glu Val Gly Ile Pro 
    370                 375                 380                 


Leu Arg Asn Thr Glu Arg Ser Lys Asp Trp Tyr Lys Thr Met Phe Lys 
385                 390                 395                 400 


Gln Ile His Lys Leu Asn Arg Asp Thr Pro Glu Glu Asn Pro Tyr Phe 
                405                 410                 415     


Pro Thr Tyr Lys Phe Pro Glu Leu Pro Glu Ile Gln Gln Thr Ser Glu 
            420                 425                 430         


Glu Thr Lys Ser Cys Ser Val Met Ser Pro Arg Leu Glu Cys Ser Gly 
        435                 440                 445             


Thr Val Ile Ala His Cys Ser Leu Lys Leu Leu Asp Ser Ser Asn Pro 
    450                 455                 460                 


Pro Thr Ser Ala Ser Gln Val Ala Gly Thr Ala Asp Asp Asp Ser Asp 
465                 470                 475                 480 


Leu Tyr Ser Pro Arg Tyr Ser Phe Ser Glu Asp Thr Lys Ser Pro Leu 
                485                 490                 495     


Ser Val Pro Arg Ser Lys Ser Glu Met Ser Tyr Ile Asp Gly Glu Lys 
            500                 505                 510         


Val Val Lys Arg Ser Ala Thr Leu Pro Leu Pro Ala Arg Ser Ser Ser 
        515                 520                 525             


Leu Lys Ser Ser Ser Glu Arg Asn Asp Trp Glu Pro Pro Asp Lys Lys 
    530                 535                 540                 


Val Asp Thr Arg Lys Tyr Arg Ala Glu Pro Lys Ser Ile Tyr Glu Tyr 
545                 550                 555                 560 


Gln Pro Gly Lys Ser Ser Val Leu Thr Asn Glu Lys Met Ser Arg Asp 
                565                 570                 575     


Ile Ser Pro Glu Glu Ile Asp Leu Lys Asn Glu Pro Trp Tyr Lys Phe 
            580                 585                 590         


Phe Ser Glu Leu Glu Phe Gly Lys Pro Pro Pro Lys Lys Ile Trp Asp 
        595                 600                 605             


Tyr Thr Pro Gly Asp Cys Ser Ile Leu Pro Arg Glu Asp Arg Lys Thr 
    610                 615                 620                 


Asn Leu Asp Lys Asp Leu Ser Leu Cys Gln Thr Glu Leu Glu Ala Asp 
625                 630                 635                 640 


Leu Glu Lys Met Glu Thr Leu Asn Lys Ala Pro Ser Ala Asn Val Pro 
                645                 650                 655     


Gln Ser Ser Ala Ile Ser Pro Thr Pro Glu Ile Ser Ser Glu Thr Pro 
            660                 665                 670         


Gly Tyr Ile Tyr Ser Ser Asn Phe His Ala Val Lys Arg Glu Ser Asp 
        675                 680                 685             


Gly Ala Pro Gly Asp Leu Thr Ser Leu Glu Asn Glu Arg Gln Ile Tyr 
    690                 695                 700                 


Lys Ser Val Leu Glu Gly Gly Asp Ile Pro Leu Gln Gly Leu Ser Gly 
705                 710                 715                 720 


Leu Lys Arg Pro Ser Ser Ser Ala Ser Thr Lys Asp Ser Glu Ser Pro 
                725                 730                 735     


Arg His Phe Ile Pro Ala Asp Tyr Leu Glu Ser Thr Glu Glu Phe Ile 
            740                 745                 750         


Arg Arg Arg His Asp Asp Lys Glu Lys Leu Leu Ala Asp Gln Arg Arg 
        755                 760                 765             


Leu Lys Arg Glu Gln Glu Glu Ala Asp Ile Ala Ala Arg Arg His Thr 
    770                 775                 780                 


Gly Val Ile Pro Thr His His Gln Phe Ile Thr Asn Glu Arg Phe Gly 
785                 790                 795                 800 


Asp Leu Leu Asn Ile Asp Asp Thr Ala Lys Arg Lys Ser Gly Ser Glu 
                805                 810                 815     


Met Arg Pro Ala Arg Ala Lys Phe Asp Phe Lys Ala Gln Thr Leu Lys 
            820                 825                 830         


Glu Leu Pro Leu Gln Lys Gly Asp Ile Val Tyr Ile Tyr Lys Gln Ile 
        835                 840                 845             


Asp Gln Asn Trp Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe 
    850                 855                 860                 


Pro Arg Thr Tyr Ile Glu Leu Leu Pro Pro Ala Glu Lys Ala Gln Pro 
865                 870                 875                 880 


Lys Lys Leu Thr Pro Val Gln Val Leu Glu Tyr Gly Glu Ala Ile Ala 
                885                 890                 895     


Lys Phe Asn Phe Asn Gly Asp Thr Gln Val Glu Met Ser Phe Arg Lys 
            900                 905                 910         


Gly Glu Arg Ile Thr Leu Leu Arg Gln Val Asp Glu Asn Trp Tyr Glu 
        915                 920                 925             


Gly Arg Ile Pro Gly Thr Ser Arg Gln Gly Ile Phe Pro Ile Thr Tyr 
    930                 935                 940                 


Val Asp Val Ile Lys Arg Pro Leu Val Lys Asn Pro Val Asp Tyr Met 
945                 950                 955                 960 


Asp Leu Pro Phe Ser Ser Ser Pro Ser Arg Ser Ala Thr Ala Ser Pro 
                965                 970                 975     


Gln Pro Trp Arg Glu Glu Ser Gly Gln Tyr Glu Arg Lys Ala Glu Arg 
            980                 985                 990         


Gly Ala Gly Glu Arg Gly Pro Gly  Gly Pro Lys Ile Ser  Lys Lys Ser 
        995                 1000                 1005             


Cys Leu  Lys Pro Ser Asp Val  Val Arg Cys Leu Ser  Thr Glu Gln 
    1010                 1015                 1020             


Arg Leu  Ser Asp Leu Asn Thr  Pro Glu Glu Ser Arg  Pro Gly Lys 
    1025                 1030                 1035             


Pro Leu  Gly Ser Ala Phe Pro  Gly Ser Glu Ala Glu  Gln Thr Glu 
    1040                 1045                 1050             


Arg His  Arg Gly Gly Glu Gln  Ala Gly Arg Lys Ala  Ala Arg Arg 
    1055                 1060                 1065             


Gly Gly  Ser Gln Gln Pro Gln  Ala Gln Gln Arg Arg  Val Thr Pro 
    1070                 1075                 1080             


Asp Arg  Ser Gln Thr Ser Gln  Asp Leu Phe Ser Tyr  Gln Ala Leu 
    1085                 1090                 1095             


Tyr Ser  Tyr Ile Pro Gln Asn  Asp Asp Glu Leu Glu  Leu Arg Asp 
    1100                 1105                 1110             


Gly Asp  Ile Val Asp Val Met  Glu Lys Cys Asp Asp  Gly Trp Phe 
    1115                 1120                 1125             


Val Gly  Thr Ser Arg Arg Thr  Lys Gln Phe Gly Thr  Phe Pro Gly 
    1130                 1135                 1140             


Asn Tyr  Val Lys Pro Leu Tyr  Leu 
    1145                 1150     


<210>  3001
<211>  839
<212>  PRT
<213>  homo sapiens

<400>  3001

Met Ser Ile Arg Arg Leu Leu Ile Leu Ile Leu Lys Ile Gly Arg Arg 
1               5                   10                  15      


Trp Thr Glu Leu Ile Arg Thr Met Glu Ser Arg Val Leu Leu Arg Thr 
            20                  25                  30          


Phe Cys Leu Ile Phe Gly Leu Gly Ala Val Trp Gly Leu Gly Val Asp 
        35                  40                  45              


Pro Ser Leu Gln Ile Asp Val Leu Thr Glu Leu Glu Leu Gly Glu Ser 
    50                  55                  60                  


Thr Thr Gly Val Arg Gln Val Pro Gly Leu His Asn Gly Thr Lys Ala 
65                  70                  75                  80  


Phe Leu Phe Gln Asp Thr Pro Arg Ser Ile Lys Ala Ser Thr Ala Thr 
                85                  90                  95      


Ala Glu Gln Phe Phe Gln Lys Leu Arg Asn Lys His Glu Phe Thr Ile 
            100                 105                 110         


Leu Val Thr Leu Lys Gln Thr His Leu Asn Ser Gly Val Ile Leu Ser 
        115                 120                 125             


Ile His His Leu Asp His Arg Tyr Leu Glu Leu Glu Ser Ser Gly His 
    130                 135                 140                 


Arg Asn Glu Val Arg Leu His Tyr Arg Ser Gly Ser His Arg Pro His 
145                 150                 155                 160 


Thr Glu Val Phe Pro Tyr Ile Leu Ala Asp Asp Lys Trp His Lys Leu 
                165                 170                 175     


Ser Leu Ala Ile Ser Ala Ser His Leu Ile Leu His Ile Asp Cys Asn 
            180                 185                 190         


Lys Ile Tyr Glu Arg Val Val Glu Lys Pro Ser Thr Asp Leu Pro Leu 
        195                 200                 205             


Gly Thr Thr Phe Trp Leu Gly Gln Arg Asn Asn Ala His Gly Tyr Phe 
    210                 215                 220                 


Lys Gly Ile Met Gln Asp Val Gln Leu Leu Val Met Pro Gln Gly Phe 
225                 230                 235                 240 


Ile Ala Gln Cys Pro Asp Leu Asn Arg Thr Cys Pro Thr Cys Asn Asp 
                245                 250                 255     


Phe His Gly Leu Val Gln Lys Ile Met Glu Leu Gln Asp Ile Leu Ala 
            260                 265                 270         


Lys Thr Ser Ala Lys Leu Ser Arg Ala Glu Gln Arg Met Asn Arg Leu 
        275                 280                 285             


Asp Gln Cys Tyr Cys Glu Arg Thr Cys Thr Met Lys Gly Thr Thr Tyr 
    290                 295                 300                 


Arg Glu Phe Glu Ser Trp Ile Asp Gly Cys Lys Asn Cys Thr Cys Leu 
305                 310                 315                 320 


Asn Gly Thr Ile Gln Cys Glu Thr Leu Ile Cys Pro Asn Pro Asp Cys 
                325                 330                 335     


Pro Leu Lys Ser Ala Leu Ala Tyr Val Asp Gly Lys Cys Cys Lys Glu 
            340                 345                 350         


Cys Lys Ser Ile Cys Gln Phe Gln Gly Arg Thr Tyr Phe Glu Gly Glu 
        355                 360                 365             


Arg Asn Thr Val Tyr Ser Ser Ser Gly Val Cys Val Leu Tyr Glu Cys 
    370                 375                 380                 


Lys Asp Gln Thr Met Lys Leu Val Glu Ser Ser Gly Cys Pro Ala Leu 
385                 390                 395                 400 


Asp Cys Pro Glu Ser His Gln Ile Thr Leu Ser His Ser Cys Cys Lys 
                405                 410                 415     


Val Cys Lys Gly Tyr Asp Phe Cys Ser Glu Arg His Asn Cys Met Glu 
            420                 425                 430         


Asn Ser Ile Cys Arg Asn Leu Asn Asp Arg Ala Val Cys Ser Cys Arg 
        435                 440                 445             


Asp Gly Phe Arg Ala Leu Arg Glu Asp Asn Ala Tyr Cys Glu Asp Ile 
    450                 455                 460                 


Asp Glu Cys Ala Glu Gly Arg His Tyr Cys Arg Glu Asn Thr Met Cys 
465                 470                 475                 480 


Val Asn Thr Pro Gly Ser Phe Met Cys Ile Cys Lys Thr Gly Tyr Ile 
                485                 490                 495     


Arg Ile Asp Asp Tyr Ser Cys Thr Glu His Asp Glu Cys Ile Thr Asn 
            500                 505                 510         


Gln His Asn Cys Asp Glu Asn Ala Leu Cys Phe Asn Thr Val Gly Gly 
        515                 520                 525             


His Asn Cys Val Cys Lys Pro Gly Tyr Thr Gly Asn Gly Thr Thr Cys 
    530                 535                 540                 


Lys Ala Phe Cys Lys Asp Gly Cys Arg Asn Gly Gly Ala Cys Ile Ala 
545                 550                 555                 560 


Ala Asn Val Cys Ala Cys Pro Gln Gly Phe Thr Gly Pro Ser Cys Glu 
                565                 570                 575     


Thr Asp Ile Asp Glu Cys Ser Asp Gly Phe Val Gln Cys Asp Ser Arg 
            580                 585                 590         


Ala Asn Cys Ile Asn Leu Pro Gly Trp Tyr His Cys Glu Cys Arg Asp 
        595                 600                 605             


Gly Tyr His Asp Asn Gly Met Phe Ser Pro Ser Gly Glu Ser Cys Glu 
    610                 615                 620                 


Asp Ile Asp Glu Cys Gly Thr Gly Arg His Ser Cys Ala Asn Asp Thr 
625                 630                 635                 640 


Ile Cys Phe Asn Leu Asp Gly Gly Tyr Asp Cys Arg Cys Pro His Gly 
                645                 650                 655     


Lys Asn Cys Thr Gly Asp Cys Ile His Asp Gly Lys Val Lys His Asn 
            660                 665                 670         


Gly Gln Ile Trp Val Leu Glu Asn Asp Arg Cys Ser Val Cys Ser Cys 
        675                 680                 685             


Gln Asn Gly Phe Val Met Cys Arg Arg Met Val Cys Asp Cys Glu Asn 
    690                 695                 700                 


Pro Thr Val Asp Leu Phe Cys Cys Pro Glu Cys Asp Pro Arg Leu Ser 
705                 710                 715                 720 


Ser Gln Cys Leu His Gln Asn Gly Glu Thr Leu Tyr Asn Ser Gly Asp 
                725                 730                 735     


Thr Trp Val Gln Asn Cys Gln Gln Cys Arg Cys Leu Gln Gly Glu Val 
            740                 745                 750         


Asp Cys Trp Pro Leu Pro Cys Pro Asp Val Glu Cys Glu Phe Ser Ile 
        755                 760                 765             


Leu Pro Glu Asn Glu Cys Cys Pro Arg Cys Val Thr Asp Pro Cys Gln 
    770                 775                 780                 


Ala Asp Thr Ile Arg Asn Asp Ile Thr Lys Thr Cys Leu Asp Glu Met 
785                 790                 795                 800 


Asn Val Val Arg Phe Thr Gly Ser Ser Trp Ile Lys His Gly Thr Glu 
                805                 810                 815     


Cys Thr Leu Cys Gln Cys Lys Asn Gly His Ile Cys Cys Ser Val Asp 
            820                 825                 830         


Pro Gln Cys Leu Gln Glu Leu 
        835                 


<210>  3002
<211>  542
<212>  PRT
<213>  homo sapiens

<400>  3002

Met Val Ala His Asp Glu Thr Gly Gly Leu Leu Pro Ile Lys Arg Thr 
1               5                   10                  15      


Ile Arg Val Leu Asp Val Asn Asn Gln Ser Phe Arg Glu Gln Glu Glu 
            20                  25                  30          


Pro Ser Asn Lys Arg Val Arg Pro Leu Ala Arg Val Thr Ser Leu Ala 
        35                  40                  45              


Asn Leu Ile Ser Pro Val Arg Asn Gly Ala Val Arg Arg Phe Gly Gln 
    50                  55                  60                  


Thr Ile Gln Ser Phe Thr Leu Arg Gly Asp His Arg Ser Pro Ala Ser 
65                  70                  75                  80  


Ala Gln Lys Phe Ser Ser Arg Ser Thr Val Pro Thr Pro Ala Lys Arg 
                85                  90                  95      


Arg Ser Ser Ala Leu Trp Ser Glu Met Leu Asp Ile Thr Met Lys Glu 
            100                 105                 110         


Ser Leu Thr Thr Arg Glu Ile Arg Arg Gln Glu Ala Ile Tyr Glu Met 
        115                 120                 125             


Ser Arg Gly Glu Gln Asp Leu Ile Glu Asp Leu Lys Leu Ala Arg Lys 
    130                 135                 140                 


Ala Tyr His Asp Pro Met Leu Lys Leu Ser Ile Met Ser Glu Glu Glu 
145                 150                 155                 160 


Leu Thr His Ile Phe Gly Asp Leu Asp Ser Tyr Ile Pro Leu His Glu 
                165                 170                 175     


Asp Leu Leu Thr Arg Ile Gly Glu Ala Thr Lys Pro Asp Gly Thr Val 
            180                 185                 190         


Glu Gln Ile Gly His Ile Leu Val Ser Trp Leu Pro Arg Leu Asn Ala 
        195                 200                 205             


Tyr Arg Gly Tyr Cys Ser Asn Gln Leu Ala Ala Lys Ala Leu Leu Asp 
    210                 215                 220                 


Gln Lys Lys Gln Asp Pro Arg Val Gln Asp Phe Leu Gln Arg Cys Leu 
225                 230                 235                 240 


Glu Ser Pro Phe Ser Arg Lys Leu Asp Leu Trp Ser Phe Leu Asp Ile 
                245                 250                 255     


Pro Arg Ser Arg Leu Val Lys Tyr Pro Leu Leu Leu Lys Glu Ile Leu 
            260                 265                 270         


Lys His Thr Pro Lys Glu His Pro Asp Val Gln Leu Leu Glu Asp Ala 
        275                 280                 285             


Ile Leu Ile Ile Gln Gly Val Leu Ser Asp Ile Asn Leu Lys Lys Gly 
    290                 295                 300                 


Glu Ser Glu Cys Gln Tyr Tyr Ile Asp Lys Leu Glu Tyr Leu Asp Glu 
305                 310                 315                 320 


Lys Gln Arg Asp Pro Arg Ile Glu Ala Ser Lys Val Leu Leu Cys His 
                325                 330                 335     


Gly Glu Leu Arg Ser Lys Ser Gly His Lys Leu Tyr Ile Phe Leu Phe 
            340                 345                 350         


Gln Asp Ile Leu Val Leu Thr Arg Pro Val Thr Arg Asn Glu Arg His 
        355                 360                 365             


Ser Tyr Gln Val Tyr Arg Gln Pro Ile Pro Val Gln Glu Leu Val Leu 
    370                 375                 380                 


Glu Asp Leu Gln Asp Gly Asp Val Arg Met Gly Gly Ser Phe Arg Gly 
385                 390                 395                 400 


Ala Phe Ser Asn Ser Glu Lys Ala Lys Asn Ile Phe Arg Ile Arg Phe 
                405                 410                 415     


His Asp Pro Ser Pro Ala Gln Ser His Thr Leu Gln Ala Asn Asp Val 
            420                 425                 430         


Phe His Lys Gln Gln Trp Phe Asn Cys Ile Arg Ala Ala Ile Ala Pro 
        435                 440                 445             


Phe Gln Ser Ala Gly Ser Pro Pro Glu Leu Gln Gly Leu Pro Glu Leu 
    450                 455                 460                 


His Glu Glu Cys Glu Gly Asn His Pro Ser Ala Arg Lys Leu Thr Ala 
465                 470                 475                 480 


Gln Arg Arg Ala Ser Thr Val Ser Ser Val Thr Gln Val Glu Val Asp 
                485                 490                 495     


Glu Asn Ala Tyr Arg Cys Gly Ser Gly Met Gln Met Ala Glu Asp Ser 
            500                 505                 510         


Lys Ser Leu Lys Thr His Gln Thr Gln Pro Gly Ile Arg Arg Ala Arg 
        515                 520                 525             


Asp Lys Ala Leu Ser Gly Gly Lys Arg Lys Glu Thr Leu Val 
    530                 535                 540         


<210>  3003
<211>  520
<212>  PRT
<213>  homo sapiens

<400>  3003

Met Pro Gly Ser Leu Pro Leu Asn Ala Glu Ala Cys Trp Pro Lys Asp 
1               5                   10                  15      


Val Gly Ile Val Ala Leu Glu Ile Tyr Phe Pro Ser Gln Tyr Val Asp 
            20                  25                  30          


Gln Ala Glu Leu Glu Lys Tyr Asp Gly Val Asp Ala Gly Lys Tyr Thr 
        35                  40                  45              


Ile Gly Leu Gly Gln Ala Lys Met Gly Phe Cys Thr Asp Arg Glu Asp 
    50                  55                  60                  


Ile Asn Ser Leu Cys Met Thr Val Val Gln Asn Leu Met Glu Arg Asn 
65                  70                  75                  80  


Asn Leu Ser Tyr Asp Cys Ile Gly Arg Leu Glu Val Gly Thr Glu Thr 
                85                  90                  95      


Ile Ile Asp Lys Ser Lys Ser Val Lys Thr Asn Leu Met Gln Leu Phe 
            100                 105                 110         


Glu Glu Ser Gly Asn Thr Asp Ile Glu Gly Ile Asp Thr Thr Asn Ala 
        115                 120                 125             


Cys Tyr Gly Gly Thr Ala Ala Val Phe Asn Ala Val Asn Trp Ile Glu 
    130                 135                 140                 


Ser Ser Ser Trp Asp Gly Arg Tyr Ala Leu Val Val Ala Gly Asp Ile 
145                 150                 155                 160 


Ala Val Tyr Ala Thr Gly Asn Ala Arg Pro Thr Gly Gly Val Gly Ala 
                165                 170                 175     


Val Ala Leu Leu Ile Gly Pro Asn Ala Pro Leu Ile Phe Glu Arg Gly 
            180                 185                 190         


Leu Arg Gly Thr His Met Gln His Ala Tyr Asp Phe Tyr Lys Pro Asp 
        195                 200                 205             


Met Leu Ser Glu Tyr Pro Ile Val Asp Gly Lys Leu Ser Ile Gln Cys 
    210                 215                 220                 


Tyr Leu Ser Ala Leu Asp Arg Cys Tyr Ser Val Tyr Cys Lys Lys Ile 
225                 230                 235                 240 


His Ala Gln Trp Gln Lys Glu Gly Asn Asp Lys Asp Phe Thr Leu Asn 
                245                 250                 255     


Asp Phe Gly Phe Met Ile Phe His Ser Pro Tyr Cys Lys Leu Val Gln 
            260                 265                 270         


Lys Ser Leu Ala Arg Met Leu Leu Asn Asp Phe Leu Asn Asp Gln Asn 
        275                 280                 285             


Arg Asp Lys Asn Ser Ile Tyr Ser Gly Leu Glu Ala Phe Gly Asp Val 
    290                 295                 300                 


Lys Leu Glu Asp Thr Tyr Phe Asp Arg Asp Val Glu Lys Ala Phe Met 
305                 310                 315                 320 


Lys Ala Ser Ser Glu Leu Phe Ser Gln Lys Thr Lys Ala Ser Leu Leu 
                325                 330                 335     


Val Ser Asn Gln Asn Gly Asn Met Tyr Thr Ser Ser Val Tyr Gly Ser 
            340                 345                 350         


Leu Ala Ser Val Leu Ala Gln Tyr Ser Pro Gln Gln Leu Ala Gly Lys 
        355                 360                 365             


Arg Ile Gly Val Phe Ser Tyr Gly Ser Gly Leu Ala Ala Thr Leu Tyr 
    370                 375                 380                 


Ser Leu Lys Val Thr Gln Asp Ala Thr Pro Gly Ser Ala Leu Asp Lys 
385                 390                 395                 400 


Ile Thr Ala Ser Leu Cys Asp Leu Lys Ser Arg Leu Asp Ser Arg Thr 
                405                 410                 415     


Gly Val Ala Pro Asp Val Phe Ala Glu Asn Met Lys Leu Arg Glu Asp 
            420                 425                 430         


Thr His His Leu Val Asn Tyr Ile Pro Gln Gly Ser Ile Asp Ser Leu 
        435                 440                 445             


Phe Glu Gly Thr Trp Tyr Leu Val Arg Val Asp Glu Lys His Arg Arg 
    450                 455                 460                 


Thr Tyr Ala Arg Arg Pro Thr Pro Asn Asp Asp Thr Leu Asp Glu Gly 
465                 470                 475                 480 


Val Gly Leu Val His Ser Asn Ile Ala Thr Glu His Ile Pro Ser Pro 
                485                 490                 495     


Ala Lys Lys Val Pro Arg Leu Pro Ala Thr Ala Ala Glu Pro Glu Ala 
            500                 505                 510         


Ala Val Ile Ser Asn Gly Glu His 
        515                 520 


<210>  3004
<211>  725
<212>  PRT
<213>  homo sapiens

<400>  3004

Met Ser Phe Pro Lys Ala Pro Leu Lys Arg Phe Asn Asp Pro Ser Gly 
1               5                   10                  15      


Cys Ala Pro Ser Pro Gly Ala Tyr Asp Val Lys Thr Leu Glu Val Leu 
            20                  25                  30          


Lys Gly Pro Val Ser Phe Gln Lys Ser Gln Arg Phe Lys Gln Gln Lys 
        35                  40                  45              


Glu Ser Lys Gln Asn Leu Asn Val Asp Lys Asp Thr Thr Leu Pro Ala 
    50                  55                  60                  


Ser Ala Arg Lys Val Lys Ser Ser Glu Ser Lys Lys Glu Ser Gln Lys 
65                  70                  75                  80  


Asn Asp Lys Asp Leu Lys Ile Leu Glu Lys Glu Ile Arg Val Leu Leu 
                85                  90                  95      


Gln Glu Arg Gly Ala Gln Asp Arg Arg Ile Gln Asp Leu Glu Thr Glu 
            100                 105                 110         


Leu Glu Lys Met Glu Ala Arg Leu Asn Ala Ala Leu Arg Glu Lys Thr 
        115                 120                 125             


Ser Leu Ser Ala Asn Asn Ala Thr Leu Glu Lys Gln Leu Ile Glu Leu 
    130                 135                 140                 


Thr Arg Thr Asn Glu Leu Leu Lys Ser Lys Phe Ser Glu Asn Gly Asn 
145                 150                 155                 160 


Gln Lys Asn Leu Arg Ile Leu Ser Leu Glu Leu Met Lys Leu Arg Asn 
                165                 170                 175     


Lys Arg Glu Thr Lys Met Arg Gly Met Met Ala Lys Gln Glu Gly Met 
            180                 185                 190         


Glu Met Lys Leu Gln Val Thr Gln Arg Ser Leu Glu Glu Ser Gln Gly 
        195                 200                 205             


Lys Ile Ala Gln Leu Glu Gly Lys Leu Val Ser Ile Glu Lys Glu Lys 
    210                 215                 220                 


Ile Asp Glu Lys Ser Glu Thr Glu Lys Leu Leu Glu Tyr Ile Glu Glu 
225                 230                 235                 240 


Ile Ser Cys Ala Ser Asp Gln Val Glu Lys Tyr Lys Leu Asp Ile Ala 
                245                 250                 255     


Gln Leu Glu Glu Asn Leu Lys Glu Lys Asn Asp Glu Ile Leu Ser Leu 
            260                 265                 270         


Lys Gln Ser Leu Glu Glu Asn Ile Val Ile Leu Ser Lys Gln Val Glu 
        275                 280                 285             


Asp Leu Asn Val Lys Cys Gln Leu Leu Glu Lys Glu Lys Glu Asp His 
    290                 295                 300                 


Val Asn Arg Asn Arg Glu His Asn Glu Asn Leu Asn Ala Glu Met Gln 
305                 310                 315                 320 


Asn Leu Lys Gln Lys Phe Ile Leu Glu Gln Gln Glu Arg Glu Lys Leu 
                325                 330                 335     


Gln Gln Lys Glu Leu Gln Ile Asp Ser Leu Leu Gln Gln Glu Lys Glu 
            340                 345                 350         


Leu Ser Ser Ser Leu His Gln Lys Leu Cys Ser Phe Gln Glu Glu Met 
        355                 360                 365             


Val Lys Glu Lys Asn Leu Phe Glu Glu Glu Leu Lys Gln Thr Leu Asp 
    370                 375                 380                 


Glu Leu Asp Lys Leu Gln Gln Lys Glu Glu Gln Ala Glu Arg Leu Val 
385                 390                 395                 400 


Lys Gln Leu Glu Glu Glu Ala Lys Ser Arg Ala Glu Glu Leu Lys Leu 
                405                 410                 415     


Leu Glu Glu Lys Leu Lys Gly Lys Glu Ala Glu Leu Glu Lys Ser Ser 
            420                 425                 430         


Ala Ala His Thr Gln Ala Thr Leu Leu Leu Gln Glu Lys Tyr Asp Ser 
        435                 440                 445             


Met Val Gln Ser Leu Glu Asp Val Thr Ala Gln Phe Glu Ser Tyr Lys 
    450                 455                 460                 


Ala Leu Thr Ala Ser Glu Ile Glu Asp Leu Lys Leu Glu Asn Ser Ser 
465                 470                 475                 480 


Leu Gln Glu Lys Ala Ala Lys Ala Gly Lys Asn Ala Glu Asp Val Gln 
                485                 490                 495     


His Gln Ile Leu Ala Thr Glu Ser Ser Asn Gln Glu Tyr Val Arg Met 
            500                 505                 510         


Leu Leu Asp Leu Gln Thr Lys Ser Ala Leu Lys Glu Thr Glu Ile Lys 
        515                 520                 525             


Glu Ile Thr Val Ser Phe Leu Gln Lys Ile Thr Asp Leu Gln Asn Gln 
    530                 535                 540                 


Leu Lys Gln Gln Glu Glu Asp Phe Arg Lys Gln Leu Glu Asp Glu Glu 
545                 550                 555                 560 


Gly Arg Lys Ala Glu Lys Glu Asn Thr Thr Ala Glu Leu Thr Glu Glu 
                565                 570                 575     


Ile Asn Lys Trp Arg Leu Leu Tyr Glu Glu Leu Tyr Asn Lys Thr Lys 
            580                 585                 590         


Pro Phe Gln Leu Gln Leu Asp Ala Phe Glu Val Glu Lys Gln Ala Leu 
        595                 600                 605             


Leu Asn Glu His Gly Ala Ala Gln Glu Gln Leu Asn Lys Ile Arg Asp 
    610                 615                 620                 


Ser Tyr Ala Lys Leu Leu Gly His Gln Asn Leu Lys Gln Lys Ile Lys 
625                 630                 635                 640 


His Val Val Lys Leu Lys Asp Glu Asn Ser Gln Leu Lys Ser Glu Val 
                645                 650                 655     


Ser Lys Leu Arg Cys Gln Leu Ala Lys Lys Lys Gln Ser Glu Thr Lys 
            660                 665                 670         


Leu Gln Glu Glu Leu Asn Lys Val Leu Gly Ile Lys His Phe Asp Pro 
        675                 680                 685             


Ser Lys Ala Phe His His Glu Ser Lys Glu Asn Phe Ala Leu Lys Thr 
    690                 695                 700                 


Pro Leu Lys Glu Gly Asn Thr Asn Cys Tyr Arg Ala Pro Met Glu Cys 
705                 710                 715                 720 


Gln Glu Ser Trp Lys 
                725 


<210>  3005
<211>  638
<212>  PRT
<213>  homo sapiens

<400>  3005

Met Thr Leu Leu Ile Arg Val Leu Leu Gln Glu Arg Gly Ala Gln Asp 
1               5                   10                  15      


Arg Arg Ile Gln Asp Leu Glu Thr Glu Leu Glu Lys Met Glu Ala Arg 
            20                  25                  30          


Leu Asn Ala Ala Leu Arg Glu Lys Thr Ser Leu Ser Ala Asn Asn Ala 
        35                  40                  45              


Thr Leu Glu Lys Gln Leu Ile Glu Leu Thr Arg Thr Asn Glu Leu Leu 
    50                  55                  60                  


Lys Ser Lys Phe Ser Glu Asn Gly Asn Gln Lys Asn Leu Arg Ile Leu 
65                  70                  75                  80  


Ser Leu Glu Leu Met Lys Leu Arg Asn Lys Arg Glu Thr Lys Met Arg 
                85                  90                  95      


Gly Met Met Ala Lys Gln Glu Gly Met Glu Met Lys Leu Gln Val Thr 
            100                 105                 110         


Gln Arg Ser Leu Glu Glu Ser Gln Gly Lys Ile Ala Gln Leu Glu Gly 
        115                 120                 125             


Lys Leu Val Ser Ile Glu Lys Glu Lys Ile Asp Glu Lys Ser Glu Thr 
    130                 135                 140                 


Glu Lys Leu Leu Glu Tyr Ile Glu Glu Ile Ser Cys Ala Ser Asp Gln 
145                 150                 155                 160 


Val Glu Lys Tyr Lys Leu Asp Ile Ala Gln Leu Glu Glu Asn Leu Lys 
                165                 170                 175     


Glu Lys Asn Asp Glu Ile Leu Ser Leu Lys Gln Ser Leu Glu Glu Asn 
            180                 185                 190         


Ile Val Ile Leu Ser Lys Gln Val Glu Asp Leu Asn Val Lys Cys Gln 
        195                 200                 205             


Leu Leu Glu Lys Glu Lys Glu Asp His Val Asn Arg Asn Arg Glu His 
    210                 215                 220                 


Asn Glu Asn Leu Asn Ala Glu Met Gln Asn Leu Lys Gln Lys Phe Ile 
225                 230                 235                 240 


Leu Glu Gln Gln Glu Arg Glu Lys Leu Gln Gln Lys Glu Leu Gln Ile 
                245                 250                 255     


Asp Ser Leu Leu Gln Gln Glu Lys Glu Leu Ser Ser Ser Leu His Gln 
            260                 265                 270         


Lys Leu Cys Ser Phe Gln Glu Glu Met Val Lys Glu Lys Asn Leu Phe 
        275                 280                 285             


Glu Glu Glu Leu Lys Gln Thr Leu Asp Glu Leu Asp Lys Leu Gln Gln 
    290                 295                 300                 


Lys Glu Glu Gln Ala Glu Arg Leu Val Lys Gln Leu Glu Glu Glu Ala 
305                 310                 315                 320 


Lys Ser Arg Ala Glu Glu Leu Lys Leu Leu Glu Glu Lys Leu Lys Gly 
                325                 330                 335     


Lys Glu Ala Glu Leu Glu Lys Ser Ser Ala Ala His Thr Gln Ala Thr 
            340                 345                 350         


Leu Leu Leu Gln Glu Lys Tyr Asp Ser Met Val Gln Ser Leu Glu Asp 
        355                 360                 365             


Val Thr Ala Gln Phe Glu Ser Tyr Lys Ala Leu Thr Ala Ser Glu Ile 
    370                 375                 380                 


Glu Asp Leu Lys Leu Glu Asn Ser Ser Leu Gln Glu Lys Ala Ala Lys 
385                 390                 395                 400 


Ala Gly Lys Asn Ala Glu Asp Val Gln His Gln Ile Leu Ala Thr Glu 
                405                 410                 415     


Ser Ser Asn Gln Glu Tyr Val Arg Met Leu Leu Asp Leu Gln Thr Lys 
            420                 425                 430         


Ser Ala Leu Lys Glu Thr Glu Ile Lys Glu Ile Thr Val Ser Phe Leu 
        435                 440                 445             


Gln Lys Ile Thr Asp Leu Gln Asn Gln Leu Lys Gln Gln Glu Glu Asp 
    450                 455                 460                 


Phe Arg Lys Gln Leu Glu Asp Glu Glu Gly Arg Lys Ala Glu Lys Glu 
465                 470                 475                 480 


Asn Thr Thr Ala Glu Leu Thr Glu Glu Ile Asn Lys Trp Arg Leu Leu 
                485                 490                 495     


Tyr Glu Glu Leu Tyr Asn Lys Thr Lys Pro Phe Gln Leu Gln Leu Asp 
            500                 505                 510         


Ala Phe Glu Val Glu Lys Gln Ala Leu Leu Asn Glu His Gly Ala Ala 
        515                 520                 525             


Gln Glu Gln Leu Asn Lys Ile Arg Asp Ser Tyr Ala Lys Leu Leu Gly 
    530                 535                 540                 


His Gln Asn Leu Lys Gln Lys Ile Lys His Val Val Lys Leu Lys Asp 
545                 550                 555                 560 


Glu Asn Ser Gln Leu Lys Ser Glu Val Ser Lys Leu Arg Cys Gln Leu 
                565                 570                 575     


Ala Lys Lys Lys Gln Ser Glu Thr Lys Leu Gln Glu Glu Leu Asn Lys 
            580                 585                 590         


Val Leu Gly Ile Lys His Phe Asp Pro Ser Lys Ala Phe His His Glu 
        595                 600                 605             


Ser Lys Glu Asn Phe Ala Leu Lys Thr Pro Leu Lys Glu Gly Asn Thr 
    610                 615                 620                 


Asn Cys Tyr Arg Ala Pro Met Glu Cys Gln Glu Ser Trp Lys 
625                 630                 635             


<210>  3006
<211>  724
<212>  PRT
<213>  homo sapiens

<400>  3006

Met Ser Phe Pro Lys Ala Pro Leu Lys Arg Phe Asn Asp Pro Ser Gly 
1               5                   10                  15      


Cys Ala Pro Ser Pro Gly Ala Tyr Asp Val Lys Thr Leu Glu Val Leu 
            20                  25                  30          


Lys Gly Pro Val Ser Phe Gln Lys Ser Gln Arg Phe Lys Gln Gln Lys 
        35                  40                  45              


Glu Ser Lys Gln Asn Leu Asn Val Asp Lys Asp Thr Thr Leu Pro Ala 
    50                  55                  60                  


Ser Ala Arg Lys Val Lys Ser Ser Glu Ser Lys Glu Ser Gln Lys Asn 
65                  70                  75                  80  


Asp Lys Asp Leu Lys Ile Leu Glu Lys Glu Ile Arg Val Leu Leu Gln 
                85                  90                  95      


Glu Arg Gly Ala Gln Asp Arg Arg Ile Gln Asp Leu Glu Thr Glu Leu 
            100                 105                 110         


Glu Lys Met Glu Ala Arg Leu Asn Ala Ala Leu Arg Glu Lys Thr Ser 
        115                 120                 125             


Leu Ser Ala Asn Asn Ala Thr Leu Glu Lys Gln Leu Ile Glu Leu Thr 
    130                 135                 140                 


Arg Thr Asn Glu Leu Leu Lys Ser Lys Phe Ser Glu Asn Gly Asn Gln 
145                 150                 155                 160 


Lys Asn Leu Arg Ile Leu Ser Leu Glu Leu Met Lys Leu Arg Asn Lys 
                165                 170                 175     


Arg Glu Thr Lys Met Arg Gly Met Met Ala Lys Gln Glu Gly Met Glu 
            180                 185                 190         


Met Lys Leu Gln Val Thr Gln Arg Ser Leu Glu Glu Ser Gln Gly Lys 
        195                 200                 205             


Ile Ala Gln Leu Glu Gly Lys Leu Val Ser Ile Glu Lys Glu Lys Ile 
    210                 215                 220                 


Asp Glu Lys Ser Glu Thr Glu Lys Leu Leu Glu Tyr Ile Glu Glu Ile 
225                 230                 235                 240 


Ser Cys Ala Ser Asp Gln Val Glu Lys Tyr Lys Leu Asp Ile Ala Gln 
                245                 250                 255     


Leu Glu Glu Asn Leu Lys Glu Lys Asn Asp Glu Ile Leu Ser Leu Lys 
            260                 265                 270         


Gln Ser Leu Glu Glu Asn Ile Val Ile Leu Ser Lys Gln Val Glu Asp 
        275                 280                 285             


Leu Asn Val Lys Cys Gln Leu Leu Glu Lys Glu Lys Glu Asp His Val 
    290                 295                 300                 


Asn Arg Asn Arg Glu His Asn Glu Asn Leu Asn Ala Glu Met Gln Asn 
305                 310                 315                 320 


Leu Lys Gln Lys Phe Ile Leu Glu Gln Gln Glu Arg Glu Lys Leu Gln 
                325                 330                 335     


Gln Lys Glu Leu Gln Ile Asp Ser Leu Leu Gln Gln Glu Lys Glu Leu 
            340                 345                 350         


Ser Ser Ser Leu His Gln Lys Leu Cys Ser Phe Gln Glu Glu Met Val 
        355                 360                 365             


Lys Glu Lys Asn Leu Phe Glu Glu Glu Leu Lys Gln Thr Leu Asp Glu 
    370                 375                 380                 


Leu Asp Lys Leu Gln Gln Lys Glu Glu Gln Ala Glu Arg Leu Val Lys 
385                 390                 395                 400 


Gln Leu Glu Glu Glu Ala Lys Ser Arg Ala Glu Glu Leu Lys Leu Leu 
                405                 410                 415     


Glu Glu Lys Leu Lys Gly Lys Glu Ala Glu Leu Glu Lys Ser Ser Ala 
            420                 425                 430         


Ala His Thr Gln Ala Thr Leu Leu Leu Gln Glu Lys Tyr Asp Ser Met 
        435                 440                 445             


Val Gln Ser Leu Glu Asp Val Thr Ala Gln Phe Glu Ser Tyr Lys Ala 
    450                 455                 460                 


Leu Thr Ala Ser Glu Ile Glu Asp Leu Lys Leu Glu Asn Ser Ser Leu 
465                 470                 475                 480 


Gln Glu Lys Ala Ala Lys Ala Gly Lys Asn Ala Glu Asp Val Gln His 
                485                 490                 495     


Gln Ile Leu Ala Thr Glu Ser Ser Asn Gln Glu Tyr Val Arg Met Leu 
            500                 505                 510         


Leu Asp Leu Gln Thr Lys Ser Ala Leu Lys Glu Thr Glu Ile Lys Glu 
        515                 520                 525             


Ile Thr Val Ser Phe Leu Gln Lys Ile Thr Asp Leu Gln Asn Gln Leu 
    530                 535                 540                 


Lys Gln Gln Glu Glu Asp Phe Arg Lys Gln Leu Glu Asp Glu Glu Gly 
545                 550                 555                 560 


Arg Lys Ala Glu Lys Glu Asn Thr Thr Ala Glu Leu Thr Glu Glu Ile 
                565                 570                 575     


Asn Lys Trp Arg Leu Leu Tyr Glu Glu Leu Tyr Asn Lys Thr Lys Pro 
            580                 585                 590         


Phe Gln Leu Gln Leu Asp Ala Phe Glu Val Glu Lys Gln Ala Leu Leu 
        595                 600                 605             


Asn Glu His Gly Ala Ala Gln Glu Gln Leu Asn Lys Ile Arg Asp Ser 
    610                 615                 620                 


Tyr Ala Lys Leu Leu Gly His Gln Asn Leu Lys Gln Lys Ile Lys His 
625                 630                 635                 640 


Val Val Lys Leu Lys Asp Glu Asn Ser Gln Leu Lys Ser Glu Val Ser 
                645                 650                 655     


Lys Leu Arg Cys Gln Leu Ala Lys Lys Lys Gln Ser Glu Thr Lys Leu 
            660                 665                 670         


Gln Glu Glu Leu Asn Lys Val Leu Gly Ile Lys His Phe Asp Pro Ser 
        675                 680                 685             


Lys Ala Phe His His Glu Ser Lys Glu Asn Phe Ala Leu Lys Thr Pro 
    690                 695                 700                 


Leu Lys Glu Gly Asn Thr Asn Cys Tyr Arg Ala Pro Met Glu Cys Gln 
705                 710                 715                 720 


Glu Ser Trp Lys 
                


<210>  3007
<211>  650
<212>  PRT
<213>  homo sapiens

<400>  3007

Met Ala Ser Pro Ala Asp Ser Cys Ile Gln Phe Thr Arg His Ala Ser 
1               5                   10                  15      


Asp Val Leu Leu Asn Leu Asn Arg Leu Arg Ser Arg Asp Ile Leu Thr 
            20                  25                  30          


Asp Val Val Ile Val Val Ser Arg Glu Gln Phe Arg Ala His Lys Thr 
        35                  40                  45              


Val Leu Met Ala Cys Ser Gly Leu Phe Tyr Ser Ile Phe Thr Asp Gln 
    50                  55                  60                  


Leu Lys Cys Asn Leu Ser Val Ile Asn Leu Asp Pro Glu Ile Asn Pro 
65                  70                  75                  80  


Glu Gly Phe Cys Ile Leu Leu Asp Phe Met Tyr Thr Ser Arg Leu Asn 
                85                  90                  95      


Leu Arg Glu Gly Asn Ile Met Ala Val Met Ala Thr Ala Met Tyr Leu 
            100                 105                 110         


Gln Met Glu His Val Val Asp Thr Cys Arg Lys Phe Ile Lys Ala Ser 
        115                 120                 125             


Glu Ala Glu Met Val Ser Ala Ile Lys Pro Pro Arg Glu Glu Phe Leu 
    130                 135                 140                 


Asn Ser Arg Met Leu Met Pro Gln Asp Ile Met Ala Tyr Arg Gly Arg 
145                 150                 155                 160 


Glu Val Val Glu Asn Asn Leu Pro Leu Arg Ser Ala Pro Gly Cys Glu 
                165                 170                 175     


Ser Arg Ala Phe Ala Pro Ser Leu Tyr Ser Gly Leu Ser Thr Pro Pro 
            180                 185                 190         


Ala Ser Tyr Ser Met Tyr Ser His Leu Pro Val Ser Ser Leu Leu Phe 
        195                 200                 205             


Ser Asp Glu Glu Phe Arg Asp Val Arg Met Pro Val Ala Asn Pro Phe 
    210                 215                 220                 


Pro Lys Glu Arg Ala Leu Pro Cys Asp Ser Ala Arg Pro Val Pro Gly 
225                 230                 235                 240 


Glu Tyr Ser Arg Pro Thr Leu Glu Val Ser Pro Asn Val Cys His Ser 
                245                 250                 255     


Asn Ile Tyr Ser Pro Lys Glu Thr Ile Pro Glu Glu Ala Arg Ser Asp 
            260                 265                 270         


Met His Tyr Ser Val Ala Glu Gly Leu Lys Pro Ala Ala Pro Ser Ala 
        275                 280                 285             


Arg Asn Ala Pro Tyr Phe Pro Cys Asp Lys Ala Ser Lys Glu Glu Glu 
    290                 295                 300                 


Arg Pro Ser Ser Glu Asp Glu Ile Ala Leu His Phe Glu Pro Pro Asn 
305                 310                 315                 320 


Ala Pro Leu Asn Arg Lys Gly Leu Val Ser Pro Gln Ser Pro Gln Lys 
                325                 330                 335     


Ser Asp Cys Gln Pro Asn Ser Pro Thr Glu Ser Cys Ser Ser Lys Asn 
            340                 345                 350         


Ala Cys Ile Leu Gln Ala Ser Gly Ser Pro Pro Ala Lys Ser Pro Thr 
        355                 360                 365             


Asp Pro Lys Ala Cys Asn Trp Lys Lys Tyr Lys Phe Ile Val Leu Asn 
    370                 375                 380                 


Ser Leu Asn Gln Asn Ala Lys Pro Glu Gly Pro Glu Gln Ala Glu Leu 
385                 390                 395                 400 


Gly Arg Leu Ser Pro Arg Ala Tyr Thr Ala Pro Pro Ala Cys Gln Pro 
                405                 410                 415     


Pro Met Glu Pro Glu Asn Leu Asp Leu Gln Ser Pro Thr Lys Leu Ser 
            420                 425                 430         


Ala Ser Gly Glu Asp Ser Thr Ile Pro Gln Ala Ser Arg Leu Asn Asn 
        435                 440                 445             


Ile Val Asn Arg Ser Met Thr Gly Ser Pro Arg Ser Ser Ser Glu Ser 
    450                 455                 460                 


His Ser Pro Leu Tyr Met His Pro Pro Lys Cys Thr Ser Cys Gly Ser 
465                 470                 475                 480 


Gln Ser Pro Gln His Ala Glu Met Cys Leu His Thr Ala Gly Pro Thr 
                485                 490                 495     


Phe Pro Glu Glu Met Gly Glu Thr Gln Ser Glu Tyr Ser Asp Ser Ser 
            500                 505                 510         


Cys Gly Glu Lys Pro Tyr Arg Cys Asn Ile Cys Gly Ala Gln Phe Asn 
        515                 520                 525             


Arg Pro Ala Asn Leu Lys Thr His Thr Arg Ile His Ser Gly Glu Lys 
    530                 535                 540                 


Pro Tyr Lys Cys Glu Thr Cys Gly Ala Arg Phe Val Gln Val Ala His 
545                 550                 555                 560 


Leu Arg Ala His Val Leu Ile His Thr Gly Glu Lys Pro Tyr Pro Cys 
                565                 570                 575     


Glu Ile Cys Gly Thr Arg Phe Arg His Leu Gln Thr Leu Lys Ser His 
            580                 585                 590         


Leu Arg Ile His Thr Gly Glu Lys Pro Tyr His Cys Glu Lys Cys Asn 
        595                 600                 605             


Leu His Phe Arg His Lys Ser Gln Leu Arg Leu His Leu Arg Gln Lys 
    610                 615                 620                 


His Gly Ala Ile Thr Asn Thr Lys Val Gln Tyr Arg Val Ser Ala Thr 
625                 630                 635                 640 


Asp Leu Pro Pro Glu Leu Pro Lys Ala Cys 
                645                 650 


<210>  3008
<211>  404
<212>  PRT
<213>  homo sapiens

<400>  3008

Met Val Gly Lys Thr Phe Thr Tyr Leu Leu Gly Ser Asp Ala Ala Ala 
1               5                   10                  15      


Leu Leu Phe Asn Ser Lys Asn Glu Asp Leu Asn Ala Glu Asp Val Tyr 
            20                  25                  30          


Ser Arg Leu Thr Thr Pro Val Phe Gly Lys Gly Val Ala Tyr Asp Val 
        35                  40                  45              


Pro Asn Pro Val Phe Leu Glu Gln Lys Lys Met Leu Lys Ser Gly Leu 
    50                  55                  60                  


Asn Ile Ala His Phe Lys Gln His Val Ser Ile Ile Glu Lys Glu Thr 
65                  70                  75                  80  


Lys Glu Tyr Phe Glu Ser Trp Gly Glu Ser Gly Glu Lys Asn Val Phe 
                85                  90                  95      


Glu Ala Leu Ser Glu Leu Ile Ile Leu Thr Ala Ser His Cys Leu His 
            100                 105                 110         


Gly Lys Glu Ile Arg Ser Gln Leu Asn Glu Lys Val Ala Gln Leu Tyr 
        115                 120                 125             


Ala Asp Leu Asp Gly Gly Phe Ser His Ala Ala Trp Leu Leu Pro Gly 
    130                 135                 140                 


Trp Leu Pro Leu Pro Ser Phe Arg Arg Arg Asp Arg Ala His Arg Glu 
145                 150                 155                 160 


Ile Lys Asp Ile Phe Tyr Lys Ala Ile Gln Lys Arg Arg Gln Ser Gln 
                165                 170                 175     


Glu Lys Ile Asp Asp Ile Leu Gln Thr Leu Leu Asp Ala Thr Tyr Lys 
            180                 185                 190         


Asp Gly Arg Pro Leu Thr Asp Asp Glu Val Ala Gly Met Leu Ile Gly 
        195                 200                 205             


Leu Leu Leu Ala Gly Gln His Thr Ser Ser Thr Thr Ser Ala Trp Met 
    210                 215                 220                 


Gly Phe Phe Leu Ala Arg Asp Lys Thr Leu Gln Lys Lys Cys Tyr Leu 
225                 230                 235                 240 


Glu Gln Lys Thr Val Cys Gly Glu Asn Leu Pro Pro Leu Thr Tyr Asp 
                245                 250                 255     


Gln Leu Lys Asp Leu Asn Leu Leu Asp Arg Cys Ile Lys Glu Thr Leu 
            260                 265                 270         


Arg Leu Arg Pro Pro Ile Met Ile Met Met Arg Met Ala Arg Thr Pro 
        275                 280                 285             


Gln Thr Val Ala Gly Tyr Thr Ile Pro Pro Gly His Gln Val Cys Val 
    290                 295                 300                 


Ser Pro Thr Val Asn Gln Arg Leu Lys Asp Ser Trp Val Glu Arg Leu 
305                 310                 315                 320 


Asp Phe Asn Pro Asp Arg Tyr Leu Gln Asp Asn Pro Ala Ser Gly Glu 
                325                 330                 335     


Lys Phe Ala Tyr Val Pro Phe Gly Ala Gly Arg His Arg Cys Ile Gly 
            340                 345                 350         


Glu Asn Phe Ala Tyr Val Gln Ile Lys Thr Ile Trp Ser Thr Met Leu 
        355                 360                 365             


Arg Leu Tyr Glu Phe Asp Leu Ile Asp Gly Tyr Phe Pro Thr Val Asn 
    370                 375                 380                 


Tyr Thr Thr Met Ile His Thr Pro Glu Asn Pro Val Ile Arg Tyr Lys 
385                 390                 395                 400 


Arg Arg Ser Lys 
                


<210>  3009
<211>  574
<212>  PRT
<213>  homo sapiens

<400>  3009

Met Ala Ser Asp Leu Glu Ser Ser Leu Thr Ser Ile Asp Trp Leu Pro 
1               5                   10                  15      


Gln Leu Thr Leu Arg Ala Thr Ile Glu Lys Leu Gly Ser Ala Ser Gln 
            20                  25                  30          


Ala Gly Pro Pro Gly Ser Ser Arg Lys Cys Ser Pro Gly Ser Pro Thr 
        35                  40                  45              


Asp Pro Asn Ala Thr Leu Ser Lys Asp Glu Ala Ala Val His Gln Asp 
    50                  55                  60                  


Gly Lys Pro Arg Tyr Ser Tyr Ala Thr Leu Ile Thr Tyr Ala Ile Asn 
65                  70                  75                  80  


Ser Ser Pro Ala Lys Lys Met Thr Leu Ser Glu Ile Tyr Arg Trp Ile 
                85                  90                  95      


Cys Asp Asn Phe Pro Tyr Tyr Lys Asn Ala Gly Ile Gly Trp Lys Asn 
            100                 105                 110         


Ser Ile Arg His Asn Leu Ser Leu Asn Lys Cys Phe Arg Lys Val Pro 
        115                 120                 125             


Arg Pro Arg Asp Asp Pro Gly Lys Gly Ser Tyr Trp Thr Ile Asp Thr 
    130                 135                 140                 


Cys Pro Asp Ile Ser Arg Lys Arg Arg His Pro Pro Asp Asp Asp Leu 
145                 150                 155                 160 


Ser Gln Asp Ser Pro Glu Gln Glu Ala Ser Lys Ser Pro Arg Gly Gly 
                165                 170                 175     


Val Ala Gly Ser Gly Glu Ala Ser Leu Pro Pro Glu Gly Asn Pro Gln 
            180                 185                 190         


Met Ser Leu Gln Ser Pro Thr Ser Ile Ala Ser Tyr Ser Gln Gly Thr 
        195                 200                 205             


Gly Ser Val Asp Gly Gly Ala Val Ala Ala Gly Ala Ser Gly Arg Glu 
    210                 215                 220                 


Ser Ala Glu Gly Pro Pro Pro Leu Tyr Asn Thr Asn His Asp Phe Lys 
225                 230                 235                 240 


Phe Ser Tyr Ser Glu Ile Asn Phe Gln Asp Leu Ser Trp Ser Phe Arg 
                245                 250                 255     


Asn Leu Tyr Lys Ser Met Leu Glu Lys Ser Ser Ser Ser Ser Gln His 
            260                 265                 270         


Gly Phe Ser Ser Leu Leu Gly Asp Ile Pro Pro Ser Asn Asn Tyr Tyr 
        275                 280                 285             


Met Tyr Gln Gln Gln Gln Pro Pro Pro Pro Gln Gln Gln Gln Gln Gln 
    290                 295                 300                 


Gln Gln Pro Pro Gln Pro Pro Pro Gln Gln Ser Gln Pro Gln Gln Gln 
305                 310                 315                 320 


Gln Ala Pro Ala Gln Gly Pro Ser Ala Val Gly Gly Ala Pro Pro Leu 
                325                 330                 335     


His Thr Pro Ser Thr Asp Gly Cys Thr Pro Pro Gly Gly Lys Gln Ala 
            340                 345                 350         


Gly Ala Glu Gly Tyr Gly Pro Pro Pro Val Met Ala Met His Pro Pro 
        355                 360                 365             


Pro Leu Gln His Gly Gly Tyr His Pro His Gln His His Pro His Ser 
    370                 375                 380                 


His Pro Ala Gln Gln Pro Pro Pro Pro Gln Pro Gln Ala Gln Gly Gln 
385                 390                 395                 400 


Ala Pro Ile Asn Asn Thr Gly Phe Ala Phe Pro Ser Asp Trp Cys Ser 
                405                 410                 415     


Asn Ile Asp Ser Leu Lys Glu Ser Phe Lys Met Val Asn Arg Leu Asn 
            420                 425                 430         


Trp Ser Ser Ile Glu Gln Ser Gln Phe Ser Glu Leu Met Glu Ser Leu 
        435                 440                 445             


Arg Gln Ala Glu Gln Lys Asn Trp Thr Leu Asp Gln His His Ile Ala 
    450                 455                 460                 


Asn Leu Cys Asp Ser Leu Asn His Phe Leu Thr Gln Thr Gly His Val 
465                 470                 475                 480 


Pro Pro Gln Gly Gly Thr His Arg Pro Pro Ala Pro Ala Arg Ile Ala 
                485                 490                 495     


Asp Ser Cys Ala Leu Thr Ser Gly Lys Gln Glu Ser Ala Met Ser Gln 
            500                 505                 510         


Val Asn Ser Tyr Gly His Pro Gln Ala Pro His Leu Tyr Pro Gly Pro 
        515                 520                 525             


Ser Pro Met Tyr Pro Ile Pro Thr Gln Asp Ser Ala Gly Tyr Asn Arg 
    530                 535                 540                 


Pro Ala His His Met Val Pro Arg Pro Ser Val Pro Pro Pro Gly Ala 
545                 550                 555                 560 


Asn Glu Glu Ile Pro Asp Asp Phe Asp Trp Asp Leu Ile Thr 
                565                 570                 


<210>  3010
<211>  483
<212>  PRT
<213>  homo sapiens

<400>  3010

Met Ser Ile Arg Val Thr Gln Lys Ser Tyr Lys Val Ser Thr Ser Gly 
1               5                   10                  15      


Pro Arg Ala Phe Ser Ser Arg Ser Tyr Thr Ser Gly Pro Gly Ser Arg 
            20                  25                  30          


Ile Ser Ser Ser Ser Phe Ser Arg Val Gly Ser Ser Asn Phe Arg Gly 
        35                  40                  45              


Gly Leu Gly Gly Gly Tyr Gly Gly Ala Ser Gly Met Gly Gly Ile Thr 
    50                  55                  60                  


Ala Val Thr Val Asn Gln Ser Leu Leu Ser Pro Leu Val Leu Glu Val 
65                  70                  75                  80  


Asp Pro Asn Ile Gln Ala Val Arg Thr Gln Glu Lys Glu Gln Ile Lys 
                85                  90                  95      


Thr Leu Asn Asn Lys Phe Ala Ser Phe Ile Asp Lys Val Arg Phe Leu 
            100                 105                 110         


Glu Gln Gln Asn Lys Met Leu Glu Thr Lys Trp Ser Leu Leu Gln Gln 
        115                 120                 125             


Gln Lys Thr Ala Arg Ser Asn Met Asp Asn Met Phe Glu Ser Tyr Ile 
    130                 135                 140                 


Asn Asn Leu Arg Arg Gln Leu Glu Thr Leu Gly Gln Glu Lys Leu Lys 
145                 150                 155                 160 


Leu Glu Ala Glu Leu Gly Asn Met Gln Gly Leu Val Glu Asp Phe Lys 
                165                 170                 175     


Asn Lys Tyr Glu Asp Glu Ile Asn Lys Arg Thr Glu Met Glu Asn Glu 
            180                 185                 190         


Phe Val Leu Ile Lys Lys Asp Val Asp Glu Ala Tyr Met Asn Lys Val 
        195                 200                 205             


Glu Leu Glu Ser Arg Leu Glu Gly Leu Thr Asp Glu Ile Asn Phe Leu 
    210                 215                 220                 


Arg Gln Leu Tyr Glu Glu Glu Ile Arg Glu Leu Gln Ser Gln Ile Ser 
225                 230                 235                 240 


Asp Thr Ser Val Val Leu Ser Met Asp Asn Ser Arg Ser Leu Asp Met 
                245                 250                 255     


Asp Ser Ile Ile Ala Glu Val Lys Ala Gln Tyr Glu Asp Ile Ala Asn 
            260                 265                 270         


Arg Ser Arg Ala Glu Ala Glu Ser Met Tyr Gln Ile Lys Tyr Glu Glu 
        275                 280                 285             


Leu Gln Ser Leu Ala Gly Lys His Gly Asp Asp Leu Arg Arg Thr Lys 
    290                 295                 300                 


Thr Glu Ile Ser Glu Met Asn Arg Asn Ile Ser Arg Leu Gln Ala Glu 
305                 310                 315                 320 


Ile Glu Gly Leu Lys Gly Gln Arg Ala Ser Leu Glu Ala Ala Ile Ala 
                325                 330                 335     


Asp Ala Glu Gln Arg Gly Glu Leu Ala Ile Lys Asp Ala Asn Ala Lys 
            340                 345                 350         


Leu Ser Glu Leu Glu Ala Ala Leu Gln Arg Ala Lys Gln Asp Met Ala 
        355                 360                 365             


Arg Gln Leu Arg Glu Tyr Gln Glu Leu Met Asn Val Lys Leu Ala Leu 
    370                 375                 380                 


Asp Ile Glu Ile Ala Thr Tyr Arg Lys Leu Leu Glu Gly Glu Glu Ser 
385                 390                 395                 400 


Arg Leu Glu Ser Gly Met Gln Asn Met Ser Ile His Thr Lys Thr Thr 
                405                 410                 415     


Ser Gly Tyr Ala Gly Gly Leu Ser Ser Ala Tyr Gly Gly Leu Thr Ser 
            420                 425                 430         


Pro Gly Leu Ser Tyr Ser Leu Gly Ser Ser Phe Gly Ser Gly Ala Gly 
        435                 440                 445             


Ser Ser Ser Phe Ser Arg Thr Ser Ser Ser Arg Ala Val Val Val Lys 
    450                 455                 460                 


Lys Ile Glu Thr Arg Asp Gly Lys Leu Val Ser Glu Ser Ser Asp Val 
465                 470                 475                 480 


Leu Pro Lys 
            


<210>  3011
<211>  608
<212>  PRT
<213>  homo sapiens

<400>  3011

Met Asn Gln Gly Ser Gly Leu Asp Leu Leu Lys Ile Ser Tyr Gly Lys 
1               5                   10                  15      


Gly Ala Arg Arg Lys Asn Arg Phe Lys Gly Ser Asp Gly Ser Thr Ser 
            20                  25                  30          


Ser Asp Thr Thr Ser Asn Ser Phe Val Arg Gln Gly Ser Ala Asp Ser 
        35                  40                  45              


Tyr Thr Ser Arg Pro Ser Asp Ser Asp Val Ser Leu Glu Glu Asp Arg 
    50                  55                  60                  


Glu Ala Val Arg Arg Glu Ala Glu Arg Gln Ala Gln Ala Gln Leu Glu 
65                  70                  75                  80  


Lys Ala Lys Thr Lys Pro Val Ala Phe Ala Val Arg Thr Asn Val Ser 
                85                  90                  95      


Tyr Ser Ala Ala His Glu Asp Asp Val Pro Val Pro Gly Met Ala Ile 
            100                 105                 110         


Ser Phe Glu Ala Lys Asp Phe Leu His Val Lys Glu Lys Phe Asn Asn 
        115                 120                 125             


Asp Trp Trp Ile Gly Arg Leu Val Lys Glu Gly Cys Glu Ile Gly Phe 
    130                 135                 140                 


Ile Pro Ser Pro Val Lys Leu Glu Asn Met Arg Leu Gln His Glu Gln 
145                 150                 155                 160 


Arg Ala Lys Gln Gly Lys Phe Tyr Ser Ser Lys Ser Gly Gly Asn Ser 
                165                 170                 175     


Ser Ser Ser Leu Gly Asp Ile Val Pro Ser Ser Arg Lys Ser Thr Pro 
            180                 185                 190         


Pro Ser Ser Gly Ala Lys Ser Ala Asp Glu Gln Asp Gln Trp Lys Thr 
        195                 200                 205             


Ala Gly Leu Phe Trp Arg Phe Thr Thr Glu His Thr Pro Pro Tyr Asp 
    210                 215                 220                 


Val Val Pro Ser Met Arg Pro Val Val Leu Val Gly Pro Ser Leu Lys 
225                 230                 235                 240 


Gly Tyr Glu Val Thr Asp Met Met Gln Lys Ala Leu Phe Asp Phe Leu 
                245                 250                 255     


Lys His Arg Phe Glu Gly Arg Ile Ser Ile Thr Arg Val Thr Ala Asp 
            260                 265                 270         


Ile Ser Leu Ala Lys Arg Ser Val Leu Asn Asn Pro Ser Lys His Ala 
        275                 280                 285             


Ile Ile Glu Arg Ser Asn Thr Arg Ser Ser Leu Ala Glu Val Gln Ser 
    290                 295                 300                 


Glu Ile Glu Arg Ile Phe Glu Leu Ala Arg Thr Leu Gln Leu Val Val 
305                 310                 315                 320 


Leu Asp Ala Asp Thr Ile Asn His Pro Ala Gln Leu Ser Lys Thr Ser 
                325                 330                 335     


Leu Ala Pro Ile Ile Val Tyr Val Lys Ile Ser Ser Pro Lys Val Leu 
            340                 345                 350         


Gln Arg Leu Ile Lys Ser Arg Gly Lys Ser Gln Ala Lys His Leu Asn 
        355                 360                 365             


Val Gln Met Val Ala Ala Asp Lys Leu Ala Gln Cys Pro Pro Glu Leu 
    370                 375                 380                 


Phe Asp Val Ile Leu Asp Glu Asn Gln Leu Glu Asp Ala Cys Glu His 
385                 390                 395                 400 


Leu Ala Asp Tyr Leu Glu Ala Tyr Trp Lys Ala Thr His Pro Pro Ser 
                405                 410                 415     


Ser Ser Leu Pro Asn Pro Leu Leu Ser Arg Thr Leu Ala Thr Ser Ser 
            420                 425                 430         


Leu Pro Leu Ser Pro Thr Leu Ala Ser Asn Ser Gln Gly Ser Gln Gly 
        435                 440                 445             


Asp Gln Arg Thr Asp Arg Ser Ala Pro Ile Arg Ser Ala Ser Gln Ala 
    450                 455                 460                 


Glu Glu Glu Pro Ser Val Glu Pro Val Lys Lys Ser Gln His Arg Ser 
465                 470                 475                 480 


Ser Ser Ser Ala Pro His His Asn His Arg Ser Gly Thr Ser Arg Gly 
                485                 490                 495     


Leu Ser Arg Gln Glu Thr Phe Asp Ser Glu Thr Gln Glu Ser Arg Asp 
            500                 505                 510         


Ser Ala Tyr Val Glu Pro Lys Glu Asp Tyr Ser His Asp His Val Asp 
        515                 520                 525             


His Tyr Ala Ser His Arg Asp His Asn His Arg Asp Glu Thr His Gly 
    530                 535                 540                 


Ser Ser Asp His Arg His Arg Glu Ser Arg His Arg Ser Arg Asp Val 
545                 550                 555                 560 


Asp Arg Glu Gln Asp His Asn Glu Cys Asn Lys Gln Arg Ser Arg His 
                565                 570                 575     


Lys Ser Lys Asp Arg Tyr Cys Glu Lys Asp Gly Glu Val Ile Ser Lys 
            580                 585                 590         


Lys Arg Asn Glu Ala Gly Glu Trp Asn Arg Asp Val Tyr Ile Arg Gln 
        595                 600                 605             


<210>  3012
<211>  524
<212>  PRT
<213>  homo sapiens

<400>  3012

Met Ile Ser Pro Phe Leu Val Leu Ala Ile Gly Thr Cys Leu Thr Asn 
1               5                   10                  15      


Ser Leu Val Pro Glu Lys Glu Lys Asp Pro Lys Tyr Trp Arg Asp Gln 
            20                  25                  30          


Ala Gln Glu Thr Leu Lys Tyr Ala Leu Glu Leu Gln Lys Leu Asn Thr 
        35                  40                  45              


Asn Val Ala Lys Asn Val Ile Met Phe Leu Gly Asp Gly Met Gly Val 
    50                  55                  60                  


Ser Thr Val Thr Ala Ala Arg Ile Leu Lys Gly Gln Leu His His Asn 
65                  70                  75                  80  


Pro Gly Glu Glu Thr Arg Leu Glu Met Asp Lys Phe Pro Phe Val Ala 
                85                  90                  95      


Leu Ser Lys Thr Tyr Asn Thr Asn Ala Gln Val Pro Asp Ser Ala Gly 
            100                 105                 110         


Thr Ala Thr Ala Tyr Leu Cys Gly Val Lys Ala Asn Glu Gly Thr Val 
        115                 120                 125             


Gly Val Ser Ala Ala Thr Glu Arg Ser Arg Cys Asn Thr Thr Gln Gly 
    130                 135                 140                 


Asn Glu Val Thr Ser Ile Leu Arg Trp Ala Lys Asp Ala Gly Lys Ser 
145                 150                 155                 160 


Val Gly Ile Val Thr Thr Thr Arg Val Asn His Ala Thr Pro Ser Ala 
                165                 170                 175     


Ala Tyr Ala His Ser Ala Asp Arg Asp Trp Tyr Ser Asp Asn Glu Met 
            180                 185                 190         


Pro Pro Glu Ala Leu Ser Gln Gly Cys Lys Asp Ile Ala Tyr Gln Leu 
        195                 200                 205             


Met His Asn Ile Arg Asp Ile Asp Val Ile Met Gly Gly Gly Arg Lys 
    210                 215                 220                 


Tyr Met Tyr Pro Lys Asn Lys Thr Asp Val Glu Tyr Glu Ser Asp Glu 
225                 230                 235                 240 


Lys Ala Arg Gly Thr Arg Leu Asp Gly Leu Asp Leu Val Asp Thr Trp 
                245                 250                 255     


Lys Ser Phe Lys Pro Arg Tyr Lys His Ser His Phe Ile Trp Asn Arg 
            260                 265                 270         


Thr Glu Leu Leu Thr Leu Asp Pro His Asn Val Asp Tyr Leu Leu Gly 
        275                 280                 285             


Leu Phe Glu Pro Gly Asp Met Gln Tyr Glu Leu Asn Arg Asn Asn Val 
    290                 295                 300                 


Thr Asp Pro Ser Leu Ser Glu Met Val Val Val Ala Ile Gln Ile Leu 
305                 310                 315                 320 


Arg Lys Asn Pro Lys Gly Phe Phe Leu Leu Val Glu Gly Gly Arg Ile 
                325                 330                 335     


Asp His Gly His His Glu Gly Lys Ala Lys Gln Ala Leu His Glu Ala 
            340                 345                 350         


Val Glu Met Asp Arg Ala Ile Gly Gln Ala Gly Ser Leu Thr Ser Ser 
        355                 360                 365             


Glu Asp Thr Leu Thr Val Val Thr Ala Asp His Ser His Val Phe Thr 
    370                 375                 380                 


Phe Gly Gly Tyr Thr Pro Arg Gly Asn Ser Ile Phe Gly Leu Ala Pro 
385                 390                 395                 400 


Met Leu Ser Asp Thr Asp Lys Lys Pro Phe Thr Ala Ile Leu Tyr Gly 
                405                 410                 415     


Asn Gly Pro Gly Tyr Lys Val Val Gly Gly Glu Arg Glu Asn Val Ser 
            420                 425                 430         


Met Val Asp Tyr Ala His Asn Asn Tyr Gln Ala Gln Ser Ala Val Pro 
        435                 440                 445             


Leu Arg His Glu Thr His Gly Gly Glu Asp Val Ala Val Phe Ser Lys 
    450                 455                 460                 


Gly Pro Met Ala His Leu Leu His Gly Val His Glu Gln Asn Tyr Val 
465                 470                 475                 480 


Pro His Val Met Ala Tyr Ala Ala Cys Ile Gly Ala Asn Leu Gly His 
                485                 490                 495     


Cys Ala Pro Ala Ser Ser Ala Gly Ser Leu Ala Ala Gly Pro Leu Leu 
            500                 505                 510         


Leu Ala Leu Ala Leu Tyr Pro Leu Ser Val Leu Phe 
        515                 520                 


<210>  3013
<211>  135
<212>  PRT
<213>  homo sapiens

<400>  3013

Met Ala Cys Gly Leu Val Ala Ser Asn Leu Asn Leu Lys Pro Gly Glu 
1               5                   10                  15      


Cys Leu Arg Val Arg Gly Glu Val Ala Pro Asp Ala Lys Ser Phe Val 
            20                  25                  30          


Leu Asn Leu Gly Lys Asp Ser Asn Asn Leu Cys Leu His Phe Asn Pro 
        35                  40                  45              


Arg Phe Asn Ala His Gly Asp Ala Asn Thr Ile Val Cys Asn Ser Lys 
    50                  55                  60                  


Asp Gly Gly Ala Trp Gly Thr Glu Gln Arg Glu Ala Val Phe Pro Phe 
65                  70                  75                  80  


Gln Pro Gly Ser Val Ala Glu Val Cys Ile Thr Phe Asp Gln Ala Asn 
                85                  90                  95      


Leu Thr Val Lys Leu Pro Asp Gly Tyr Glu Phe Lys Phe Pro Asn Arg 
            100                 105                 110         


Leu Asn Leu Glu Ala Ile Asn Tyr Met Ala Ala Asp Gly Asp Phe Lys 
        115                 120                 125             


Ile Lys Cys Val Ala Phe Asp 
    130                 135 


<210>  3014
<211>  153
<212>  PRT
<213>  homo sapiens

<400>  3014

Met Leu Arg Phe Ile Gln Glu Val Asn Thr Thr Thr Arg Ser Cys Ala 
1               5                   10                  15      


Leu Trp Asp Leu Glu Glu Asp Thr Glu Tyr Ile Val His Val Gln Ala 
            20                  25                  30          


Ile Ser Ile Gln Gly Gln Ser Pro Ala Ser Glu Pro Val Leu Phe Lys 
        35                  40                  45              


Thr Pro Arg Glu Ala Glu Lys Met Ala Ser Lys Asn Lys Asp Glu Val 
    50                  55                  60                  


Thr Met Lys Glu Met Gly Arg Asn Gln Gln Leu Arg Thr Gly Glu Val 
65                  70                  75                  80  


Leu Ile Ile Val Val Val Leu Phe Met Trp Ala Gly Val Ile Ala Leu 
                85                  90                  95      


Phe Cys Arg Gln Tyr Asp Ile Ile Lys Asp Asn Glu Pro Asn Asn Asn 
            100                 105                 110         


Lys Glu Lys Thr Lys Ser Ala Ser Glu Thr Ser Thr Pro Glu His Gln 
        115                 120                 125             


Gly Gly Gly Leu Leu Arg Ser Lys Val Arg Ala Arg Pro Gly Pro Gly 
    130                 135                 140                 


Trp Ala Thr Leu Cys Leu Met Leu Trp 
145                 150             


<210>  3015
<211>  639
<212>  PRT
<213>  homo sapiens

<400>  3015

Met Ala Thr Gly Ala Asn Ala Thr Pro Leu Asp Phe Pro Ser Lys Lys 
1               5                   10                  15      


Arg Lys Arg Ser Arg Trp Asn Gln Asp Thr Met Glu Gln Lys Thr Val 
            20                  25                  30          


Ile Pro Gly Met Pro Thr Val Ile Pro Pro Gly Leu Thr Arg Glu Gln 
        35                  40                  45              


Glu Arg Ala Tyr Ile Val Gln Leu Gln Ile Glu Asp Leu Thr Arg Lys 
    50                  55                  60                  


Leu Arg Thr Gly Asp Leu Gly Ile Pro Pro Asn Pro Glu Asp Arg Ser 
65                  70                  75                  80  


Pro Ser Pro Glu Pro Ile Tyr Asn Ser Glu Gly Lys Arg Leu Asn Thr 
                85                  90                  95      


Arg Glu Phe Arg Thr Arg Lys Lys Leu Glu Glu Glu Arg His Asn Leu 
            100                 105                 110         


Ile Thr Glu Met Val Ala Leu Asn Pro Asp Phe Lys Pro Pro Ala Asp 
        115                 120                 125             


Tyr Lys Pro Pro Ala Thr Arg Val Ser Asp Lys Val Met Ile Pro Gln 
    130                 135                 140                 


Asp Glu Tyr Pro Glu Ile Asn Phe Val Gly Leu Leu Ile Gly Pro Arg 
145                 150                 155                 160 


Gly Asn Thr Leu Lys Asn Ile Glu Lys Glu Cys Asn Ala Lys Ile Met 
                165                 170                 175     


Ile Arg Gly Lys Gly Ser Val Lys Glu Gly Lys Val Gly Arg Lys Asp 
            180                 185                 190         


Gly Gln Met Leu Pro Gly Glu Asp Glu Pro Leu His Ala Leu Val Thr 
        195                 200                 205             


Ala Asn Thr Met Glu Asn Val Lys Lys Ala Val Glu Gln Ile Arg Asn 
    210                 215                 220                 


Ile Leu Lys Gln Gly Ile Glu Thr Pro Glu Asp Gln Asn Asp Leu Arg 
225                 230                 235                 240 


Lys Met Gln Leu Arg Glu Leu Ala Arg Leu Asn Gly Thr Leu Arg Glu 
                245                 250                 255     


Asp Asp Asn Arg Ile Leu Arg Pro Trp Gln Ser Ser Glu Thr Arg Ser 
            260                 265                 270         


Ile Thr Asn Thr Thr Val Cys Thr Lys Cys Gly Gly Ala Gly His Ile 
        275                 280                 285             


Ala Ser Asp Cys Lys Phe Gln Arg Pro Gly Asp Pro Gln Ser Ala Gln 
    290                 295                 300                 


Asp Lys Ala Arg Met Asp Lys Glu Tyr Leu Ser Leu Met Ala Glu Leu 
305                 310                 315                 320 


Gly Glu Ala Pro Val Pro Ala Ser Val Gly Ser Thr Ser Gly Pro Ala 
                325                 330                 335     


Thr Thr Pro Leu Ala Ser Ala Pro Arg Pro Ala Ala Pro Ala Asn Asn 
            340                 345                 350         


Pro Pro Pro Pro Ser Leu Met Ser Thr Thr Gln Ser Arg Pro Pro Trp 
        355                 360                 365             


Met Asn Ser Gly Pro Ser Glu Ser Arg Pro Tyr His Gly Met His Gly 
    370                 375                 380                 


Gly Gly Pro Gly Gly Pro Gly Gly Gly Pro His Ser Phe Pro His Pro 
385                 390                 395                 400 


Leu Pro Ser Leu Thr Gly Gly His Gly Gly His Pro Met Gln His Asn 
                405                 410                 415     


Pro Asn Gly Pro Pro Pro Pro Trp Met Gln Pro Pro Pro Pro Pro Met 
            420                 425                 430         


Asn Gln Gly Pro His Pro Pro Gly His His Gly Pro Pro Pro Met Asp 
        435                 440                 445             


Gln Tyr Leu Gly Ser Thr Pro Val Gly Ser Gly Val Tyr Arg Leu His 
    450                 455                 460                 


Gln Gly Lys Gly Met Met Pro Pro Pro Pro Met Gly Met Met Pro Pro 
465                 470                 475                 480 


Pro Pro Pro Pro Pro Ser Gly Gln Pro Pro Pro Pro Pro Ser Gly Pro 
                485                 490                 495     


Leu Pro Pro Trp Gln Gln Gln Gln Gln Gln Pro Pro Pro Pro Pro Pro 
            500                 505                 510         


Pro Ser Ser Ser Met Ala Ser Ser Thr Pro Leu Pro Trp Gln Gln Asn 
        515                 520                 525             


Thr Thr Thr Thr Thr Thr Ser Ala Gly Thr Gly Ser Ile Pro Pro Trp 
    530                 535                 540                 


Gln Gln Gln Gln Ala Ala Ala Ala Ala Ser Pro Gly Ala Pro Gln Met 
545                 550                 555                 560 


Gln Gly Asn Pro Thr Met Val Pro Leu Pro Pro Gly Val Gln Pro Pro 
                565                 570                 575     


Leu Pro Pro Gly Ala Pro Pro Pro Pro Pro Pro Pro Pro Pro Gly Ser 
            580                 585                 590         


Ala Gly Met Met Tyr Ala Pro Pro Pro Pro Pro Pro Pro Pro Met Asp 
        595                 600                 605             


Pro Ser Asn Phe Val Thr Met Met Gly Met Gly Val Ala Gly Met Pro 
    610                 615                 620                 


Pro Phe Gly Met Pro Pro Ala Pro Pro Pro Pro Pro Pro Gln Asn 
625                 630                 635                 


<210>  3016
<211>  571
<212>  PRT
<213>  homo sapiens

<400>  3016

Met Ala Thr Gly Ala Asn Ala Thr Pro Leu Asp Phe Pro Ser Lys Lys 
1               5                   10                  15      


Arg Lys Arg Ser Arg Trp Asn Gln Asp Thr Met Glu Gln Lys Thr Val 
            20                  25                  30          


Ile Pro Gly Met Pro Thr Val Ile Pro Pro Gly Leu Thr Arg Glu Gln 
        35                  40                  45              


Glu Arg Ala Tyr Ile Val Gln Leu Gln Ile Glu Asp Leu Thr Arg Lys 
    50                  55                  60                  


Leu Arg Thr Gly Asp Leu Gly Ile Pro Pro Asn Pro Glu Asp Arg Ser 
65                  70                  75                  80  


Pro Ser Pro Glu Pro Ile Tyr Asn Ser Glu Gly Lys Arg Leu Asn Thr 
                85                  90                  95      


Arg Glu Phe Arg Thr Arg Lys Lys Leu Glu Glu Glu Arg His Asn Leu 
            100                 105                 110         


Ile Thr Glu Met Val Ala Leu Asn Pro Asp Phe Lys Pro Pro Ala Asp 
        115                 120                 125             


Tyr Lys Pro Pro Ala Thr Arg Val Ser Asp Lys Val Met Ile Pro Gln 
    130                 135                 140                 


Asp Glu Tyr Pro Glu Ile Asn Phe Val Gly Leu Leu Ile Gly Pro Arg 
145                 150                 155                 160 


Gly Asn Thr Leu Lys Asn Ile Glu Lys Glu Cys Asn Ala Lys Ile Met 
                165                 170                 175     


Ile Arg Gly Lys Gly Ser Val Lys Glu Gly Lys Val Gly Arg Lys Asp 
            180                 185                 190         


Gly Gln Met Leu Pro Gly Glu Asp Glu Pro Leu His Ala Leu Val Thr 
        195                 200                 205             


Ala Asn Thr Met Glu Asn Val Lys Lys Ala Val Glu Gln Ile Arg Asn 
    210                 215                 220                 


Ile Leu Lys Gln Gly Ile Glu Thr Pro Glu Asp Gln Asn Asp Leu Arg 
225                 230                 235                 240 


Lys Met Gln Leu Arg Glu Leu Ala Arg Leu Asn Gly Thr Leu Arg Glu 
                245                 250                 255     


Asp Asp Asn Arg Ile Leu Arg Pro Trp Gln Ser Ser Glu Thr Arg Ser 
            260                 265                 270         


Ile Thr Asn Thr Thr Val Cys Thr Lys Cys Gly Gly Ala Gly His Ile 
        275                 280                 285             


Ala Ser Asp Cys Lys Phe Gln Arg Pro Gly Asp Pro Gln Ser Ala Gln 
    290                 295                 300                 


Asp Lys Ala Arg Met Asp Lys Glu Tyr Leu Ser Leu Met Ala Glu Leu 
305                 310                 315                 320 


Gly Glu Ala Pro Val Pro Ala Ser Val Gly Ser Thr Ser Gly Pro Ala 
                325                 330                 335     


Thr Thr Pro Leu Ala Ser Ala Pro Arg Pro Ala Ala Pro Ala Asn Asn 
            340                 345                 350         


Pro Pro Pro Pro Ser Leu Met Ser Thr Thr Gln Ser Arg Pro Pro Trp 
        355                 360                 365             


Met Asn Ser Gly Pro Ser Glu Ser Arg Pro Tyr His Gly Met His Gly 
    370                 375                 380                 


Gly Gly Pro Gly Gly Pro Gly Gly Gly Pro His Ser Phe Pro His Pro 
385                 390                 395                 400 


Leu Pro Ser Leu Thr Gly Gly His Gly Gly His Pro Met Gln His Asn 
                405                 410                 415     


Pro Asn Gly Pro Pro Pro Pro Trp Met Gln Pro Pro Pro Pro Pro Met 
            420                 425                 430         


Asn Gln Gly Pro His Pro Pro Gly His His Gly Pro Pro Pro Met Gly 
        435                 440                 445             


Lys Ser Val Pro Gly Lys Tyr Ala Cys Gly Leu Trp Gly Leu Ser Pro 
    450                 455                 460                 


Ala Ser Arg Lys Arg Tyr Asp Ala Ala Thr Thr Tyr Gly His Asp Ala 
465                 470                 475                 480 


Ala Ala Ala Ala Ala Ser Gln Trp Ala Ala Pro Thr Pro Ser Leu Trp 
                485                 490                 495     


Ser Ser Ser Pro Met Ala Thr Thr Ala Ala Ala Ala Ser Ala Thr Pro 
            500                 505                 510         


Ser Ala Gln Gln Gln Tyr Gly Phe Gln Tyr Pro Leu Ala Met Ala Ala 
        515                 520                 525             


Lys Ile Pro Pro Arg Gly Gly Asp Gly Pro Ser His Glu Ser Glu Asp 
    530                 535                 540                 


Phe Pro Arg Pro Leu Val Thr Leu Pro Gly Arg Gln Pro Gln Gln Arg 
545                 550                 555                 560 


Pro Trp Trp Thr Gly Trp Phe Gly Lys Ala Ala 
                565                 570     


<210>  3017
<211>  332
<212>  PRT
<213>  homo sapiens

<400>  3017

Met Leu Leu Lys Glu Tyr Arg Ile Cys Met Pro Leu Thr Val Asp Glu 
1               5                   10                  15      


Tyr Lys Ile Gly Gln Leu Tyr Met Ile Ser Lys His Ser His Glu Gln 
            20                  25                  30          


Ser Asp Arg Gly Glu Gly Val Glu Val Val Gln Asn Glu Pro Phe Glu 
        35                  40                  45              


Asp Pro His His Gly Asn Gly Gln Phe Thr Glu Lys Arg Val Tyr Leu 
    50                  55                  60                  


Asn Ser Lys Leu Pro Ser Trp Ala Arg Ala Val Val Pro Lys Ile Phe 
65                  70                  75                  80  


Tyr Val Thr Glu Lys Ala Trp Asn Tyr Tyr Pro Tyr Thr Ile Thr Glu 
                85                  90                  95      


Tyr Thr Cys Ser Phe Leu Pro Lys Phe Ser Ile His Ile Glu Thr Lys 
            100                 105                 110         


Tyr Glu Asp Asn Lys Gly Ser Asn Asp Thr Ile Phe Asp Asn Glu Ala 
        115                 120                 125             


Lys Asp Val Glu Arg Glu Val Cys Phe Ile Asp Ile Ala Cys Asp Glu 
    130                 135                 140                 


Ile Pro Glu Arg Tyr Tyr Lys Glu Ser Glu Asp Pro Lys His Phe Lys 
145                 150                 155                 160 


Ser Glu Lys Thr Gly Arg Gly Gln Leu Arg Glu Gly Trp Arg Asp Ser 
                165                 170                 175     


His Gln Pro Ile Met Cys Ser Tyr Lys Leu Val Thr Val Lys Phe Glu 
            180                 185                 190         


Val Trp Gly Leu Gln Thr Arg Val Glu Gln Phe Val His Lys Val Val 
        195                 200                 205             


Arg Asp Ile Leu Leu Ile Gly His Arg Gln Ala Phe Ala Trp Val Asp 
    210                 215                 220                 


Glu Trp Tyr Asp Met Thr Met Asp Glu Val Arg Glu Phe Glu Arg Ala 
225                 230                 235                 240 


Thr Gln Glu Ala Thr Asn Lys Lys Ile Gly Ile Phe Pro Pro Ala Ile 
                245                 250                 255     


Ser Ile Ser Ser Ile Pro Leu Leu Pro Ser Ser Val Arg Ser Ala Pro 
            260                 265                 270         


Ser Ser Ala Pro Ser Thr Pro Leu Ser Thr Asp Ala Pro Glu Phe Leu 
        275                 280                 285             


Ser Val Pro Lys Asp Arg Pro Arg Lys Lys Ser Ala Pro Glu Thr Leu 
    290                 295                 300                 


Thr Leu Pro Asp Pro Glu Lys Lys Ala Thr Leu Asn Leu Pro Gly Met 
305                 310                 315                 320 


His Ser Ser Asp Lys Pro Cys Arg Pro Lys Ser Glu 
                325                 330         


<210>  3018
<211>  509
<212>  PRT
<213>  homo sapiens

<400>  3018

Met Tyr Ser Pro Leu Cys Leu Thr Gln Asp Glu Phe His Pro Phe Ile 
1               5                   10                  15      


Glu Ala Leu Leu Pro His Val Arg Ala Phe Ala Tyr Thr Trp Phe Asn 
            20                  25                  30          


Leu Gln Ala Arg Lys Arg Lys Tyr Phe Lys Lys His Glu Lys Arg Met 
        35                  40                  45              


Ser Lys Glu Glu Glu Arg Ala Val Lys Asp Glu Leu Leu Ser Glu Lys 
    50                  55                  60                  


Pro Glu Val Lys Gln Lys Trp Ala Ser Arg Leu Leu Ala Lys Leu Arg 
65                  70                  75                  80  


Lys Asp Ile Arg Pro Glu Tyr Arg Glu Asp Phe Val Leu Thr Val Thr 
                85                  90                  95      


Gly Lys Lys Pro Pro Cys Cys Val Leu Ser Asn Pro Asp Gln Lys Gly 
            100                 105                 110         


Lys Met Arg Arg Ile Asp Cys Leu Arg Gln Ala Asp Lys Val Trp Arg 
        115                 120                 125             


Leu Asp Leu Val Met Val Ile Leu Phe Lys Gly Ile Pro Leu Glu Ser 
    130                 135                 140                 


Thr Asp Gly Glu Arg Leu Val Lys Ser Pro Gln Cys Ser Asn Pro Gly 
145                 150                 155                 160 


Leu Cys Val Gln Pro His His Ile Gly Val Ser Val Lys Glu Leu Asp 
                165                 170                 175     


Leu Tyr Leu Ala Tyr Phe Val His Ala Ala Asp Ser Ser Gln Ser Glu 
            180                 185                 190         


Ser Pro Ser Gln Pro Ser Asp Ala Asp Ile Lys Asp Gln Pro Glu Asn 
        195                 200                 205             


Gly His Leu Gly Phe Gln Asp Ser Phe Val Thr Ser Gly Val Phe Ser 
    210                 215                 220                 


Val Thr Glu Leu Val Arg Val Ser Gln Thr Pro Ile Ala Ala Gly Thr 
225                 230                 235                 240 


Gly Pro Asn Phe Ser Leu Ser Asp Leu Glu Ser Ser Ser Tyr Tyr Ser 
                245                 250                 255     


Met Ser Pro Gly Ala Met Arg Arg Ser Leu Pro Ser Thr Ser Ser Thr 
            260                 265                 270         


Ser Ser Thr Lys Arg Leu Lys Ser Val Glu Asp Glu Met Asp Ser Pro 
        275                 280                 285             


Gly Glu Glu Pro Phe Tyr Thr Gly Gln Gly Arg Ser Pro Gly Ser Gly 
    290                 295                 300                 


Ser Gln Ser Ser Gly Trp His Glu Val Glu Pro Gly Met Pro Ser Pro 
305                 310                 315                 320 


Thr Thr Leu Lys Lys Ser Glu Lys Ser Gly Phe Ser Ser Pro Ser Pro 
                325                 330                 335     


Ser Gln Thr Ser Ser Leu Gly Thr Ala Phe Thr Gln His His Arg Pro 
            340                 345                 350         


Val Ile Thr Gly Pro Arg Ala Ser Pro His Ala Thr Pro Ser Thr Leu 
        355                 360                 365             


His Phe Pro Thr Ser Pro Ile Ile Gln Gln Pro Gly Pro Tyr Phe Ser 
    370                 375                 380                 


His Pro Ala Ile Arg Tyr His Pro Gln Glu Thr Leu Lys Glu Phe Val 
385                 390                 395                 400 


Gln Leu Val Cys Pro Asp Ala Gly Gln Gln Ala Gly Gln Val Gly Phe 
                405                 410                 415     


Leu Asn Pro Asn Gly Ser Ser Gln Gly Lys Val His Asn Pro Phe Leu 
            420                 425                 430         


Pro Thr Pro Met Leu Pro Pro Pro Pro Pro Pro Pro Met Ala Arg Pro 
        435                 440                 445             


Val Pro Leu Pro Val Pro Asp Thr Lys Pro Pro Thr Thr Ser Thr Glu 
    450                 455                 460                 


Gly Gly Ala Ala Ser Pro Thr Ser Pro Thr Tyr Ser Thr Pro Ser Thr 
465                 470                 475                 480 


Ser Pro Ala Asn Arg Phe Val Ser Val Gly Pro Arg Asp Pro Ser Phe 
                485                 490                 495     


Val Asn Ile Pro Gln Gln Thr Gln Ser Trp Tyr Leu Gly 
            500                 505                 


<210>  3019
<211>  467
<212>  PRT
<213>  homo sapiens

<400>  3019

Met Pro Gly Arg Trp Arg Trp Gln Arg Asp Met His Pro Ala Arg Lys 
1               5                   10                  15      


Leu Leu Ser Leu Leu Phe Leu Ile Leu Met Gly Thr Glu Leu Thr Gln 
            20                  25                  30          


Val Leu Pro Thr Asn Pro Glu Glu Ser Trp Gln Val Tyr Ser Ser Ala 
        35                  40                  45              


Gln Asp Ser Glu Gly Arg Cys Ile Cys Thr Val Val Ala Pro Gln Gln 
    50                  55                  60                  


Thr Met Cys Ser Arg Asp Ala Arg Thr Lys Gln Leu Arg Gln Leu Leu 
65                  70                  75                  80  


Glu Lys Val Gln Asn Met Ser Gln Ser Ile Glu Val Leu Asp Arg Arg 
                85                  90                  95      


Thr Gln Arg Asp Leu Gln Tyr Val Glu Lys Met Glu Asn Gln Met Lys 
            100                 105                 110         


Gly Leu Glu Ser Lys Phe Lys Gln Val Glu Glu Ser His Lys Gln His 
        115                 120                 125             


Leu Ala Arg Gln Phe Lys Ala Ile Lys Ala Lys Met Asp Glu Leu Arg 
    130                 135                 140                 


Pro Leu Ile Pro Val Leu Glu Glu Tyr Lys Ala Asp Ala Lys Leu Val 
145                 150                 155                 160 


Leu Gln Phe Lys Glu Glu Val Gln Asn Leu Thr Ser Val Leu Asn Glu 
                165                 170                 175     


Leu Gln Glu Glu Ile Gly Ala Tyr Asp Tyr Asp Glu Leu Gln Ser Arg 
            180                 185                 190         


Val Ser Asn Leu Glu Glu Arg Leu Arg Ala Cys Met Gln Lys Leu Ala 
        195                 200                 205             


Cys Gly Lys Leu Thr Gly Ile Ser Asp Pro Val Thr Val Lys Thr Ser 
    210                 215                 220                 


Gly Ser Arg Phe Gly Ser Trp Met Thr Asp Pro Leu Ala Pro Glu Gly 
225                 230                 235                 240 


Asp Asn Arg Val Trp Tyr Met Asp Gly Tyr His Asn Asn Arg Phe Val 
                245                 250                 255     


Arg Glu Tyr Lys Ser Met Val Asp Phe Met Asn Thr Asp Asn Phe Thr 
            260                 265                 270         


Ser His Arg Leu Pro His Pro Trp Ser Gly Thr Gly Gln Val Val Tyr 
        275                 280                 285             


Asn Gly Ser Ile Tyr Phe Asn Lys Phe Gln Ser His Ile Ile Ile Arg 
    290                 295                 300                 


Phe Asp Leu Lys Thr Glu Thr Ile Leu Lys Thr Arg Ser Leu Asp Tyr 
305                 310                 315                 320 


Ala Gly Tyr Asn Asn Met Tyr His Tyr Ala Trp Gly Gly His Ser Asp 
                325                 330                 335     


Ile Asp Leu Met Val Asp Glu Ser Gly Leu Trp Ala Val Tyr Ala Thr 
            340                 345                 350         


Asn Gln Asn Ala Gly Asn Ile Val Val Ser Arg Leu Asp Pro Val Ser 
        355                 360                 365             


Leu Gln Thr Leu Gln Thr Trp Asn Thr Ser Tyr Pro Lys Arg Ser Ala 
    370                 375                 380                 


Gly Glu Ala Phe Ile Ile Cys Gly Thr Leu Tyr Val Thr Asn Gly Tyr 
385                 390                 395                 400 


Ser Gly Gly Thr Lys Val His Tyr Ala Tyr Gln Thr Asn Ala Ser Thr 
                405                 410                 415     


Tyr Glu Tyr Ile Asp Ile Pro Phe Gln Asn Lys Tyr Ser His Ile Ser 
            420                 425                 430         


Met Leu Asp Tyr Asn Pro Lys Asp Arg Ala Leu Tyr Ala Trp Asn Asn 
        435                 440                 445             


Gly His Gln Ile Leu Tyr Asn Val Thr Leu Phe His Val Ile Arg Ser 
    450                 455                 460                 


Asp Glu Leu 
465         


<210>  3020
<211>  360
<212>  PRT
<213>  homo sapiens

<400>  3020

Met Glu Leu Asp Phe Gly His Phe Asp Glu Arg Asp Lys Thr Ser Arg 
1               5                   10                  15      


Asn Met Arg Gly Ser Arg Met Asn Gly Leu Pro Ser Pro Thr His Ser 
            20                  25                  30          


Ala His Cys Ser Phe Tyr Arg Thr Arg Thr Leu Gln Ala Leu Ser Asn 
        35                  40                  45              


Glu Lys Lys Ala Lys Lys Val Arg Phe Tyr Arg Asn Gly Asp Arg Tyr 
    50                  55                  60                  


Phe Lys Gly Ile Val Tyr Ala Val Ser Ser Asp Arg Phe Arg Ser Phe 
65                  70                  75                  80  


Asp Ala Leu Leu Ala Asp Leu Thr Arg Ser Leu Ser Asp Asn Ile Asn 
                85                  90                  95      


Leu Pro Gln Gly Val Arg Tyr Ile Tyr Thr Ile Asp Gly Ser Arg Lys 
            100                 105                 110         


Ile Gly Ser Met Asp Glu Leu Glu Glu Gly Glu Ser Tyr Val Cys Ser 
        115                 120                 125             


Ser Asp Asn Phe Phe Lys Lys Val Glu Tyr Thr Lys Asn Val Asn Pro 
    130                 135                 140                 


Asn Trp Ser Val Asn Val Lys Thr Ser Ala Asn Met Lys Ala Pro Gln 
145                 150                 155                 160 


Ser Leu Ala Ser Ser Asn Ser Ala Gln Ala Arg Glu Asn Lys Asp Phe 
                165                 170                 175     


Val Arg Pro Lys Leu Val Thr Ile Ile Arg Ser Gly Val Lys Pro Arg 
            180                 185                 190         


Lys Ala Val Arg Val Leu Leu Asn Lys Lys Thr Ala His Ser Phe Glu 
        195                 200                 205             


Gln Val Leu Thr Asp Ile Thr Glu Ala Ile Lys Leu Glu Thr Gly Val 
    210                 215                 220                 


Val Lys Lys Leu Tyr Thr Leu Asp Gly Lys Gln Val Thr Cys Leu His 
225                 230                 235                 240 


Asp Phe Phe Gly Asp Asp Asp Val Phe Ile Ala Cys Gly Pro Glu Lys 
                245                 250                 255     


Phe Arg Tyr Ala Gln Asp Asp Phe Ser Leu Asp Glu Asn Glu Cys Arg 
            260                 265                 270         


Val Met Lys Gly Asn Pro Ser Ala Thr Ala Gly Pro Lys Ala Ser Pro 
        275                 280                 285             


Thr Pro Gln Lys Thr Ser Ala Lys Ser Pro Gly Pro Met Arg Arg Ser 
    290                 295                 300                 


Lys Ser Pro Ala Asp Ser Ala Asn Gly Thr Ser Ser Ser Gln Leu Ser 
305                 310                 315                 320 


Thr Pro Lys Ser Lys Gln Ser Pro Ile Ser Thr Pro Thr Ser Pro Gly 
                325                 330                 335     


Ser Leu Arg Lys His Lys Asp Leu Tyr Leu Pro Leu Ser Leu Asp Asp 
            340                 345                 350         


Ser Asp Ser Leu Gly Asp Ser Met 
        355                 360 


<210>  3021
<211>  465
<212>  PRT
<213>  homo sapiens

<400>  3021

Met Ala Met Thr Gly Ser Thr Pro Cys Ser Ser Met Ser Asn His Thr 
1               5                   10                  15      


Lys Glu Arg Val Thr Met Thr Lys Val Thr Leu Glu Asn Phe Tyr Ser 
            20                  25                  30          


Asn Leu Ile Ala Gln His Glu Glu Arg Glu Met Arg Gln Lys Lys Leu 
        35                  40                  45              


Glu Lys Val Met Glu Glu Glu Gly Leu Lys Asp Glu Glu Lys Arg Leu 
    50                  55                  60                  


Arg Arg Ser Ala His Ala Arg Lys Glu Thr Glu Phe Leu Arg Leu Lys 
65                  70                  75                  80  


Arg Thr Arg Leu Gly Leu Glu Asp Phe Glu Ser Leu Lys Val Ile Gly 
                85                  90                  95      


Arg Gly Ala Phe Gly Glu Val Arg Leu Val Gln Lys Lys Asp Thr Gly 
            100                 105                 110         


His Val Tyr Ala Met Lys Ile Leu Arg Lys Ala Asp Met Leu Glu Lys 
        115                 120                 125             


Glu Gln Val Gly His Ile Arg Ala Glu Arg Asp Ile Leu Val Glu Ala 
    130                 135                 140                 


Asp Ser Leu Trp Val Val Lys Met Phe Tyr Ser Phe Gln Asp Lys Leu 
145                 150                 155                 160 


Asn Leu Tyr Leu Ile Met Glu Phe Leu Pro Gly Gly Asp Met Met Thr 
                165                 170                 175     


Leu Leu Met Lys Lys Asp Thr Leu Thr Glu Glu Glu Thr Gln Phe Tyr 
            180                 185                 190         


Ile Ala Glu Thr Val Leu Ala Ile Asp Ser Ile His Gln Leu Gly Phe 
        195                 200                 205             


Ile His Arg Asp Ile Lys Pro Asp Asn Leu Leu Leu Asp Ser Lys Gly 
    210                 215                 220                 


His Val Lys Leu Ser Asp Phe Gly Leu Cys Thr Gly Leu Lys Lys Ala 
225                 230                 235                 240 


His Arg Thr Glu Phe Tyr Arg Asn Leu Asn His Ser Leu Pro Ser Asp 
                245                 250                 255     


Phe Thr Phe Gln Asn Met Asn Ser Lys Arg Lys Ala Glu Thr Trp Lys 
            260                 265                 270         


Arg Asn Arg Arg Gln Leu Ala Phe Ser Thr Val Gly Thr Pro Asp Tyr 
        275                 280                 285             


Ile Ala Pro Glu Val Phe Met Gln Thr Gly Tyr Asn Lys Leu Cys Asp 
    290                 295                 300                 


Trp Trp Ser Leu Gly Val Ile Met Tyr Glu Met Leu Ile Gly Tyr Pro 
305                 310                 315                 320 


Pro Phe Cys Ser Glu Thr Pro Gln Glu Thr Tyr Lys Lys Val Met Asn 
                325                 330                 335     


Trp Lys Glu Thr Leu Thr Phe Pro Pro Glu Val Pro Ile Ser Glu Lys 
            340                 345                 350         


Ala Lys Asp Leu Ile Leu Arg Phe Cys Cys Glu Trp Glu His Arg Ile 
        355                 360                 365             


Gly Ala Pro Gly Val Glu Glu Ile Lys Ser Asn Ser Phe Phe Glu Gly 
    370                 375                 380                 


Val Asp Trp Glu His Ile Arg Glu Arg Pro Ala Ala Ile Ser Ile Glu 
385                 390                 395                 400 


Ile Lys Ser Ile Asp Asp Thr Ser Asn Phe Asp Glu Phe Pro Glu Ser 
                405                 410                 415     


Asp Ile Leu Lys Pro Thr Val Ala Thr Ser Asn His Pro Glu Thr Asp 
            420                 425                 430         


Tyr Lys Asn Lys Asp Trp Val Phe Ile Asn Tyr Thr Tyr Lys Arg Phe 
        435                 440                 445             


Glu Gly Leu Thr Ala Arg Gly Ala Ile Pro Ser Tyr Met Lys Ala Ala 
    450                 455                 460                 


Lys 
465 


<210>  3022
<211>  545
<212>  PRT
<213>  homo sapiens

<400>  3022

Met Ala Glu Pro Ser Gly Ser Pro Val His Val Gln Leu Pro Gln Gln 
1               5                   10                  15      


Ala Ala Pro Val Thr Ala Ala Ala Ala Ala Ala Pro Ala Ala Ala Thr 
            20                  25                  30          


Ala Ala Pro Ala Pro Ala Ala Pro Ala Ala Pro Ala Pro Ala Pro Ala 
        35                  40                  45              


Pro Ala Ala Gln Ala Val Gly Trp Pro Ile Cys Arg Asp Ala Tyr Glu 
    50                  55                  60                  


Leu Gln Glu Val Ile Gly Ser Gly Ala Thr Ala Val Val Gln Ala Ala 
65                  70                  75                  80  


Leu Cys Lys Pro Arg Gln Glu Arg Val Ala Ile Lys Arg Ile Asn Leu 
                85                  90                  95      


Glu Lys Cys Gln Thr Ser Met Asp Glu Leu Leu Lys Glu Ile Gln Ala 
            100                 105                 110         


Met Ser Gln Cys Ser His Pro Asn Val Val Thr Tyr Tyr Thr Ser Phe 
        115                 120                 125             


Val Val Lys Asp Glu Leu Trp Leu Val Met Lys Leu Leu Ser Gly Gly 
    130                 135                 140                 


Ser Met Leu Asp Ile Ile Lys Tyr Ile Val Asn Arg Gly Glu His Lys 
145                 150                 155                 160 


Asn Gly Val Leu Glu Glu Ala Ile Ile Ala Thr Ile Leu Lys Glu Val 
                165                 170                 175     


Leu Glu Gly Leu Asp Tyr Leu His Arg Asn Gly Gln Ile His Arg Asp 
            180                 185                 190         


Leu Lys Ala Gly Asn Ile Leu Leu Gly Glu Asp Gly Ser Val Gln Ile 
        195                 200                 205             


Ala Asp Phe Gly Val Ser Ala Phe Leu Ala Thr Gly Gly Asp Val Thr 
    210                 215                 220                 


Arg Asn Lys Val Arg Lys Thr Phe Val Gly Thr Pro Cys Trp Met Ala 
225                 230                 235                 240 


Pro Glu Val Met Glu Gln Val Arg Gly Tyr Asp Phe Lys Ala Asp Met 
                245                 250                 255     


Trp Ser Phe Gly Ile Thr Ala Ile Glu Leu Ala Thr Gly Ala Ala Pro 
            260                 265                 270         


Tyr His Lys Tyr Pro Pro Met Lys Val Leu Met Leu Thr Leu Gln Asn 
        275                 280                 285             


Asp Pro Pro Thr Leu Glu Thr Gly Val Glu Asp Lys Glu Met Met Lys 
    290                 295                 300                 


Lys Tyr Gly Lys Ser Phe Arg Lys Leu Leu Ser Leu Cys Leu Gln Lys 
305                 310                 315                 320 


Asp Pro Ser Lys Arg Pro Thr Ala Ala Glu Leu Leu Lys Cys Lys Phe 
                325                 330                 335     


Phe Gln Lys Ala Lys Asn Arg Glu Tyr Leu Ile Glu Lys Leu Leu Thr 
            340                 345                 350         


Arg Thr Pro Asp Ile Ala Gln Arg Ala Lys Lys Val Arg Arg Val Pro 
        355                 360                 365             


Gly Ser Ser Gly His Leu His Lys Thr Glu Asp Gly Asp Trp Glu Trp 
    370                 375                 380                 


Ser Asp Asp Glu Met Asp Glu Lys Ser Glu Glu Gly Lys Ala Ala Phe 
385                 390                 395                 400 


Ser Gln Glu Lys Ser Arg Arg Val Lys Glu Glu Asn Pro Glu Ile Ala 
                405                 410                 415     


Val Ser Ala Ser Thr Ile Pro Glu Gln Ile Gln Ser Leu Ser Val His 
            420                 425                 430         


Asp Ser Gln Gly Pro Pro Asn Ala Asn Glu Asp Tyr Arg Glu Ala Ser 
        435                 440                 445             


Ser Cys Ala Val Asn Leu Val Leu Arg Leu Arg Asn Ser Arg Lys Glu 
    450                 455                 460                 


Leu Asn Asp Ile Arg Phe Glu Phe Thr Pro Gly Arg Asp Thr Ala Asp 
465                 470                 475                 480 


Gly Val Ser Gln Glu Leu Phe Ser Ala Gly Leu Val Asp Gly His Asp 
                485                 490                 495     


Val Val Ile Val Ala Ala Asn Leu Gln Lys Ile Val Asp Asp Pro Lys 
            500                 505                 510         


Ala Leu Lys Thr Leu Thr Phe Lys Leu Ala Ser Gly Cys Asp Gly Ser 
        515                 520                 525             


Glu Ile Pro Asp Glu Val Lys Leu Ile Gly Phe Ala Gln Leu Ser Val 
    530                 535                 540                 


Ser 
545 


<210>  3023
<211>  180
<212>  PRT
<213>  homo sapiens

<400>  3023

Met Ala Ser Thr Ile Ser Ala Tyr Lys Glu Lys Met Lys Glu Leu Ser 
1               5                   10                  15      


Val Leu Ser Leu Ile Cys Ser Cys Phe Tyr Thr Gln Pro His Pro Asn 
            20                  25                  30          


Thr Val Tyr Gln Tyr Gly Asp Met Glu Val Lys Gln Leu Asp Lys Arg 
        35                  40                  45              


Ala Ser Gly Gln Ser Phe Glu Val Ile Leu Lys Ser Pro Ser Asp Leu 
    50                  55                  60                  


Ser Pro Glu Ser Pro Met Leu Ser Ser Pro Pro Lys Lys Lys Asp Thr 
65                  70                  75                  80  


Ser Leu Glu Glu Leu Gln Lys Arg Leu Glu Ala Ala Glu Glu Arg Arg 
                85                  90                  95      


Lys Thr Gln Glu Ala Gln Val Leu Lys Gln Leu Ala Glu Arg Arg Glu 
            100                 105                 110         


His Glu Arg Glu Val Leu His Lys Ala Leu Glu Glu Asn Asn Asn Phe 
        115                 120                 125             


Ser Arg Gln Ala Glu Glu Lys Leu Asn Tyr Lys Met Glu Leu Ser Lys 
    130                 135                 140                 


Glu Ile Arg Glu Ala His Leu Ala Ala Leu Arg Glu Arg Leu Arg Glu 
145                 150                 155                 160 


Lys Glu Leu His Ala Ala Glu Val Arg Arg Asn Lys Glu Gln Arg Glu 
                165                 170                 175     


Glu Met Ser Gly 
            180 


<210>  3024
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  3024

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Met Gln Asp Leu 
1               5                   10                  15      


Leu Glu Ser Thr Asp Phe Thr Glu His Glu Ile Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Arg Asp Cys Pro Ser Gly His Leu Ser Met Glu Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Gly Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Ala Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Lys Ala Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Glu Lys Ile Phe Arg Gln Met Asp Thr Asn Arg 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Gly Gln 
            180                 185                 190         


Phe 
    


<210>  3025
<211>  508
<212>  PRT
<213>  homo sapiens

<400>  3025

Met Leu Pro Thr Gln Ala Gly Ala Ala Ala Ala Leu Gly Arg Gly Ser 
1               5                   10                  15      


Ala Leu Gly Gly Ser Leu Asn Arg Thr Pro Thr Gly Arg Pro Gly Gly 
            20                  25                  30          


Gly Gly Gly Thr Arg Gly Ala Asn Gly Gly Arg Val Pro Gly Asn Gly 
        35                  40                  45              


Ala Gly Leu Gly Pro Gly Arg Leu Glu Arg Glu Ala Ala Ala Ala Ala 
    50                  55                  60                  


Ala Thr Thr Pro Ala Pro Thr Ala Gly Ala Leu Tyr Ser Gly Ser Glu 
65                  70                  75                  80  


Gly Asp Ser Glu Ser Gly Glu Glu Glu Glu Leu Gly Ala Glu Arg Arg 
                85                  90                  95      


Gly Leu Lys Arg Ser Leu Ser Glu Met Glu Ile Gly Met Val Val Gly 
            100                 105                 110         


Gly Pro Glu Ala Ser Ala Ala Ala Thr Gly Gly Tyr Gly Pro Val Ser 
        115                 120                 125             


Gly Ala Val Ser Gly Ala Lys Pro Gly Lys Lys Thr Arg Gly Arg Val 
    130                 135                 140                 


Lys Ile Lys Met Glu Phe Ile Asp Asn Lys Leu Arg Arg Tyr Thr Thr 
145                 150                 155                 160 


Phe Ser Lys Arg Lys Thr Gly Ile Met Lys Lys Ala Tyr Glu Leu Ser 
                165                 170                 175     


Thr Leu Thr Gly Thr Gln Val Leu Leu Leu Val Ala Ser Glu Thr Gly 
            180                 185                 190         


His Val Tyr Thr Phe Ala Thr Arg Lys Leu Gln Pro Met Ile Thr Ser 
        195                 200                 205             


Glu Thr Gly Lys Ala Leu Ile Gln Thr Cys Leu Asn Ser Pro Asp Ser 
    210                 215                 220                 


Pro Pro Arg Ser Asp Pro Thr Thr Asp Gln Arg Met Ser Ala Thr Gly 
225                 230                 235                 240 


Phe Glu Glu Thr Asp Leu Thr Tyr Gln Val Ser Glu Ser Asp Ser Ser 
                245                 250                 255     


Gly Glu Thr Lys Asp Thr Leu Lys Pro Ala Phe Thr Val Thr Asn Leu 
            260                 265                 270         


Pro Gly Thr Thr Ser Thr Ile Gln Thr Ala Pro Ser Thr Ser Thr Thr 
        275                 280                 285             


Met Gln Val Ser Ser Gly Pro Ser Phe Pro Ile Thr Asn Tyr Leu Ala 
    290                 295                 300                 


Pro Val Ser Ala Ser Val Ser Pro Ser Ala Val Ser Ser Ala Asn Gly 
305                 310                 315                 320 


Thr Val Leu Lys Ser Thr Gly Ser Gly Pro Val Ser Ser Gly Gly Leu 
                325                 330                 335     


Met Gln Leu Pro Thr Ser Phe Thr Leu Met Pro Gly Gly Ala Val Ala 
            340                 345                 350         


Gln Gln Val Pro Val Gln Ala Ile Gln Val His Gln Ala Pro Gln Gln 
        355                 360                 365             


Ala Ser Pro Ser Arg Asp Ser Ser Thr Asp Leu Thr Gln Thr Ser Ser 
    370                 375                 380                 


Ser Gly Thr Val Thr Leu Pro Ala Thr Ile Met Thr Ser Ser Val Pro 
385                 390                 395                 400 


Thr Thr Val Gly Gly His Met Met Tyr Pro Ser Pro His Ala Val Met 
                405                 410                 415     


Tyr Ala Pro Thr Ser Gly Leu Gly Asp Gly Ser Leu Thr Val Leu Asn 
            420                 425                 430         


Ala Phe Ser Gln Ala Pro Ser Thr Met Gln Val Ser His Ser Gln Val 
        435                 440                 445             


Gln Glu Pro Gly Gly Val Pro Gln Val Phe Leu Thr Ala Ser Ser Gly 
    450                 455                 460                 


Thr Val Gln Ile Pro Val Ser Ala Val Gln Leu His Gln Met Ala Val 
465                 470                 475                 480 


Ile Gly Gln Gln Ala Gly Ser Ser Ser Asn Leu Thr Glu Leu Gln Val 
                485                 490                 495     


Val Asn Leu Asp Thr Ala His Ser Thr Lys Ser Glu 
            500                 505             


<210>  3026
<211>  372
<212>  PRT
<213>  homo sapiens

<400>  3026

Met Asn Gly Pro Cys Gln Ser Leu Arg Lys Ala Glu Gly Leu Leu Glu 
1               5                   10                  15      


Gly Cys Thr Ser Ala Val Thr Val Phe Arg Lys Leu Pro Leu Asp Ser 
            20                  25                  30          


Lys Ala Gln Ser Gln Lys Met Arg Tyr Lys Thr Ser Leu Val Met Arg 
        35                  40                  45              


Lys Arg Leu Arg Leu Tyr Arg Asn Thr Leu Lys Glu Ser Ser Ser Ser 
    50                  55                  60                  


Ser Gly His His Gly Pro Gln Leu Thr Ala Ala Ser Ser Pro Ser Val 
65                  70                  75                  80  


Phe Pro Gly Leu His Glu Glu Pro Pro Gln Ala Ser Pro Ser Arg Pro 
                85                  90                  95      


Leu Asn Gly Leu Leu Arg Leu Gly Leu Pro Gly Asp Met Tyr Ala Arg 
            100                 105                 110         


Pro Glu Pro Phe Pro Pro Gly Pro Ala Ala Arg Ser Asp Ala Leu Ala 
        115                 120                 125             


Ala Ala Ala Ala Leu His Gly Tyr Gly Gly Met Asn Leu Thr Val Asn 
    130                 135                 140                 


Leu Ala Ala Pro His Gly Pro Gly Ala Phe Phe Arg Tyr Met Arg Gln 
145                 150                 155                 160 


Pro Ile Lys Gln Glu Leu Ile Cys Lys Trp Leu Ala Ala Asp Gly Thr 
                165                 170                 175     


Ala Thr Pro Ser Leu Cys Ser Lys Thr Phe Ser Thr Met His Glu Leu 
            180                 185                 190         


Val Thr His Val Thr Val Glu His Val Gly Gly Pro Glu Gln Ala Asn 
        195                 200                 205             


His Ile Cys Phe Trp Glu Glu Cys Pro Arg Gln Gly Lys Pro Phe Lys 
    210                 215                 220                 


Ala Lys Tyr Lys Leu Val Asn His Ile Arg Val His Thr Gly Glu Lys 
225                 230                 235                 240 


Pro Phe Pro Cys Pro Phe Pro Gly Cys Gly Lys Val Phe Ala Arg Ser 
                245                 250                 255     


Glu Asn Leu Lys Ile His Lys Arg Thr His Thr Gly Glu Lys Pro Phe 
            260                 265                 270         


Arg Cys Glu Phe Glu Gly Cys Glu Arg Arg Phe Ala Asn Ser Ser Asp 
        275                 280                 285             


Arg Lys Lys His Ser His Val His Thr Ser Asp Lys Pro Tyr Thr Cys 
    290                 295                 300                 


Lys Val Arg Gly Cys Asp Lys Cys Tyr Thr His Pro Ser Ser Leu Arg 
305                 310                 315                 320 


Lys His Met Lys Val His Gly Arg Ser Pro Pro Pro Ser Ser Gly Tyr 
                325                 330                 335     


Asp Ser Ala Thr Pro Ser Ala Leu Val Ser Pro Ser Ser Asp Cys Gly 
            340                 345                 350         


His Lys Ser Gln Val Ala Ser Ser Ala Ala Val Ala Ala Arg Thr Ala 
        355                 360                 365             


Asp Leu Ser Glu 
    370         


<210>  3027
<211>  199
<212>  PRT
<213>  homo sapiens

<400>  3027

Met Asp Gly Gln Lys Lys Asn Trp Lys Asp Lys Val Val Asp Leu Leu 
1               5                   10                  15      


Tyr Trp Arg Asp Ile Lys Lys Thr Gly Val Val Phe Gly Ala Ser Leu 
            20                  25                  30          


Phe Leu Leu Leu Ser Leu Thr Val Phe Ser Ile Val Ser Val Thr Ala 
        35                  40                  45              


Tyr Ile Ala Leu Ala Leu Leu Ser Val Thr Ile Ser Phe Arg Ile Tyr 
    50                  55                  60                  


Lys Gly Val Ile Gln Ala Ile Gln Lys Ser Asp Glu Gly His Pro Phe 
65                  70                  75                  80  


Arg Ala Tyr Leu Glu Ser Glu Val Ala Ile Ser Glu Glu Leu Val Gln 
                85                  90                  95      


Lys Tyr Ser Asn Ser Ala Leu Gly His Val Asn Cys Thr Ile Lys Glu 
            100                 105                 110         


Leu Arg Arg Leu Phe Leu Val Asp Asp Leu Val Asp Ser Leu Lys Phe 
        115                 120                 125             


Ala Val Leu Met Trp Val Phe Thr Tyr Val Gly Ala Leu Phe Asn Gly 
    130                 135                 140                 


Leu Thr Leu Leu Ile Leu Ala Leu Ile Ser Leu Phe Ser Val Pro Val 
145                 150                 155                 160 


Ile Tyr Glu Arg His Gln Ala Gln Ile Asp His Tyr Leu Gly Leu Ala 
                165                 170                 175     


Asn Lys Asn Val Lys Asp Ala Met Ala Lys Ile Gln Ala Lys Ile Pro 
            180                 185                 190         


Gly Leu Lys Arg Lys Ala Glu 
        195                 


<210>  3028
<211>  301
<212>  PRT
<213>  homo sapiens

<400>  3028

Met Pro Gly Ile Ser Ser Gln Ile Leu Thr Asn Ala Gln Gly Gln Val 
1               5                   10                  15      


Ile Gly Thr Leu Pro Trp Val Val Asn Ser Ala Ser Val Ala Ala Pro 
            20                  25                  30          


Ala Pro Ala Gln Ser Leu Gln Val Gln Ala Val Thr Pro Gln Leu Leu 
        35                  40                  45              


Leu Asn Ala Gln Gly Gln Val Ile Ala Thr Leu Ala Ser Ser Pro Leu 
    50                  55                  60                  


Pro Pro Pro Val Ala Val Arg Lys Pro Ser Thr Pro Glu Ser Pro Ala 
65                  70                  75                  80  


Lys Ser Glu Val Gln Pro Ile Gln Pro Thr Pro Thr Val Pro Gln Pro 
                85                  90                  95      


Ala Val Val Ile Ala Ser Pro Ala Pro Ala Ala Lys Pro Ser Ala Ser 
            100                 105                 110         


Ala Pro Ile Pro Ile Thr Cys Ser Glu Thr Pro Thr Val Ser Gln Leu 
        115                 120                 125             


Val Ser Lys Pro His Thr Pro Ser Leu Asp Glu Asp Gly Ile Asn Leu 
    130                 135                 140                 


Glu Glu Ile Arg Glu Phe Ala Lys Asn Phe Lys Ile Arg Arg Leu Ser 
145                 150                 155                 160 


Leu Gly Leu Thr Gln Thr Gln Val Gly Gln Ala Leu Thr Ala Thr Glu 
                165                 170                 175     


Gly Pro Ala Tyr Ser Gln Ser Ala Ile Cys Arg Phe Glu Lys Leu Asp 
            180                 185                 190         


Ile Thr Pro Lys Ser Ala Gln Lys Leu Lys Pro Val Leu Glu Lys Trp 
        195                 200                 205             


Leu Asn Glu Ala Glu Leu Arg Asn Gln Glu Gly Gln Gln Asn Leu Met 
    210                 215                 220                 


Glu Phe Val Gly Gly Glu Pro Ser Lys Lys Arg Lys Arg Arg Thr Ser 
225                 230                 235                 240 


Phe Thr Pro Gln Ala Ile Glu Ala Leu Asn Ala Tyr Phe Glu Lys Asn 
                245                 250                 255     


Pro Leu Pro Thr Gly Gln Glu Ile Thr Glu Ile Ala Lys Glu Leu Asn 
            260                 265                 270         


Tyr Asp Arg Glu Val Val Arg Val Trp Phe Cys Asn Arg Arg Gln Thr 
        275                 280                 285             


Leu Lys Asn Thr Ser Lys Leu Asn Val Phe Gln Ile Pro 
    290                 295                 300     


<210>  3029
<211>  469
<212>  PRT
<213>  homo sapiens

<400>  3029

Met Phe Leu Gly Asp Gly Met Gly Val Ser Thr Val Thr Ala Ala Arg 
1               5                   10                  15      


Ile Leu Lys Gly Gln Leu His His Asn Pro Gly Glu Glu Thr Arg Leu 
            20                  25                  30          


Glu Met Asp Lys Phe Pro Phe Val Ala Leu Ser Lys Thr Tyr Asn Thr 
        35                  40                  45              


Asn Ala Gln Val Pro Asp Ser Ala Gly Thr Ala Thr Ala Tyr Leu Cys 
    50                  55                  60                  


Gly Val Lys Ala Asn Glu Gly Thr Val Gly Val Ser Ala Ala Thr Glu 
65                  70                  75                  80  


Arg Ser Arg Cys Asn Thr Thr Gln Gly Asn Glu Val Thr Ser Ile Leu 
                85                  90                  95      


Arg Trp Ala Lys Asp Ala Gly Lys Ser Val Gly Ile Val Thr Thr Thr 
            100                 105                 110         


Arg Val Asn His Ala Thr Pro Ser Ala Ala Tyr Ala His Ser Ala Asp 
        115                 120                 125             


Arg Asp Trp Tyr Ser Asp Asn Glu Met Pro Pro Glu Ala Leu Ser Gln 
    130                 135                 140                 


Gly Cys Lys Asp Ile Ala Tyr Gln Leu Met His Asn Ile Arg Asp Ile 
145                 150                 155                 160 


Asp Val Ile Met Gly Gly Gly Arg Lys Tyr Met Tyr Pro Lys Asn Lys 
                165                 170                 175     


Thr Asp Val Glu Tyr Glu Ser Asp Glu Lys Ala Arg Gly Thr Arg Leu 
            180                 185                 190         


Asp Gly Leu Asp Leu Val Asp Thr Trp Lys Ser Phe Lys Pro Arg Tyr 
        195                 200                 205             


Lys His Ser His Phe Ile Trp Asn Arg Thr Glu Leu Leu Thr Leu Asp 
    210                 215                 220                 


Pro His Asn Val Asp Tyr Leu Leu Gly Leu Phe Glu Pro Gly Asp Met 
225                 230                 235                 240 


Gln Tyr Glu Leu Asn Arg Asn Asn Val Thr Asp Pro Ser Leu Ser Glu 
                245                 250                 255     


Met Val Val Val Ala Ile Gln Ile Leu Arg Lys Asn Pro Lys Gly Phe 
            260                 265                 270         


Phe Leu Leu Val Glu Gly Gly Arg Ile Asp His Gly His His Glu Gly 
        275                 280                 285             


Lys Ala Lys Gln Ala Leu His Glu Ala Val Glu Met Asp Arg Ala Ile 
    290                 295                 300                 


Gly Gln Ala Gly Ser Leu Thr Ser Ser Glu Asp Thr Leu Thr Val Val 
305                 310                 315                 320 


Thr Ala Asp His Ser His Val Phe Thr Phe Gly Gly Tyr Thr Pro Arg 
                325                 330                 335     


Gly Asn Ser Ile Phe Gly Leu Ala Pro Met Leu Ser Asp Thr Asp Lys 
            340                 345                 350         


Lys Pro Phe Thr Ala Ile Leu Tyr Gly Asn Gly Pro Gly Tyr Lys Val 
        355                 360                 365             


Val Gly Gly Glu Arg Glu Asn Val Ser Met Val Asp Tyr Ala His Asn 
    370                 375                 380                 


Asn Tyr Gln Ala Gln Ser Ala Val Pro Leu Arg His Glu Thr His Gly 
385                 390                 395                 400 


Gly Glu Asp Val Ala Val Phe Ser Lys Gly Pro Met Ala His Leu Leu 
                405                 410                 415     


His Gly Val His Glu Gln Asn Tyr Val Pro His Val Met Ala Tyr Ala 
            420                 425                 430         


Ala Cys Ile Gly Ala Asn Leu Gly His Cys Ala Pro Ala Ser Ser Ala 
        435                 440                 445             


Gly Ser Leu Ala Ala Gly Pro Leu Leu Leu Ala Leu Ala Leu Tyr Pro 
    450                 455                 460                 


Leu Ser Val Leu Phe 
465                 


<210>  3030
<211>  406
<212>  PRT
<213>  homo sapiens

<400>  3030

Met Thr Thr Pro Ala Asn Ala Gln Asn Ala Ser Lys Thr Trp Glu Leu 
1               5                   10                  15      


Ser Leu Tyr Glu Leu His Arg Thr Pro Gln Glu Ala Ile Met Asp Gly 
            20                  25                  30          


Thr Glu Ile Ala Val Ser Pro Arg Ser Leu His Ser Glu Leu Met Cys 
        35                  40                  45              


Pro Ile Cys Leu Asp Met Leu Lys Asn Thr Met Thr Thr Lys Glu Cys 
    50                  55                  60                  


Leu His Arg Phe Cys Ser Asp Cys Ile Val Thr Ala Leu Arg Ser Gly 
65                  70                  75                  80  


Asn Lys Glu Cys Pro Thr Cys Arg Lys Lys Leu Val Ser Lys Arg Ser 
                85                  90                  95      


Leu Arg Pro Asp Pro Asn Phe Asp Ala Leu Ile Ser Lys Ile Tyr Pro 
            100                 105                 110         


Ser Arg Glu Glu Tyr Glu Ala His Gln Asp Arg Val Leu Ile Arg Leu 
        115                 120                 125             


Ser Arg Leu His Asn Gln Gln Ala Leu Ser Ser Ser Ile Glu Glu Gly 
    130                 135                 140                 


Leu Arg Met Gln Ala Met His Arg Ala Gln Arg Val Arg Arg Pro Ile 
145                 150                 155                 160 


Pro Gly Ser Asp Gln Thr Thr Thr Met Ser Gly Gly Glu Gly Glu Pro 
                165                 170                 175     


Gly Glu Gly Glu Gly Asp Gly Glu Asp Val Ser Ser Asp Ser Ala Pro 
            180                 185                 190         


Asp Ser Ala Pro Gly Pro Ala Pro Lys Arg Pro Arg Gly Gly Gly Ala 
        195                 200                 205             


Gly Gly Ser Ser Val Gly Thr Gly Gly Gly Gly Thr Gly Gly Val Gly 
    210                 215                 220                 


Gly Gly Ala Gly Ser Glu Asp Ser Gly Asp Arg Gly Gly Thr Leu Gly 
225                 230                 235                 240 


Gly Gly Thr Leu Gly Pro Pro Ser Pro Pro Gly Ala Pro Ser Pro Pro 
                245                 250                 255     


Glu Pro Gly Gly Glu Ile Glu Leu Val Phe Arg Pro His Pro Leu Leu 
            260                 265                 270         


Val Glu Lys Gly Glu Tyr Cys Gln Thr Arg Tyr Val Lys Thr Thr Gly 
        275                 280                 285             


Asn Ala Thr Val Asp His Leu Ser Lys Tyr Leu Ala Leu Arg Ile Ala 
    290                 295                 300                 


Leu Glu Arg Arg Gln Gln Gln Glu Ala Gly Glu Pro Gly Gly Pro Gly 
305                 310                 315                 320 


Gly Gly Ala Ser Asp Thr Gly Gly Pro Asp Gly Cys Gly Gly Glu Gly 
                325                 330                 335     


Gly Gly Ala Gly Gly Gly Asp Gly Pro Glu Glu Pro Ala Leu Pro Ser 
            340                 345                 350         


Leu Glu Gly Val Ser Glu Lys Gln Tyr Thr Ile Tyr Ile Ala Pro Gly 
        355                 360                 365             


Gly Gly Ala Phe Thr Thr Leu Asn Gly Ser Leu Thr Leu Glu Leu Val 
    370                 375                 380                 


Asn Glu Lys Phe Trp Lys Val Ser Arg Pro Leu Glu Leu Cys Tyr Ala 
385                 390                 395                 400 


Pro Thr Lys Asp Pro Lys 
                405     


<210>  3031
<211>  457
<212>  PRT
<213>  homo sapiens

<400>  3031

Met Tyr Glu Ser Val Glu Val Gly Gly Pro Thr Pro Asn Pro Phe Leu 
1               5                   10                  15      


Val Val Asp Phe Tyr Asn Gln Asn Arg Ala Cys Leu Leu Pro Glu Lys 
            20                  25                  30          


Gly Leu Pro Ala Pro Gly Pro Tyr Ser Thr Pro Leu Arg Thr Pro Leu 
        35                  40                  45              


Trp Asn Gly Ser Asn His Ser Ile Glu Thr Gln Ser Ser Ser Ser Glu 
    50                  55                  60                  


Glu Ile Val Pro Ser Pro Pro Ser Pro Pro Pro Leu Pro Arg Ile Tyr 
65                  70                  75                  80  


Lys Pro Cys Phe Val Cys Gln Asp Lys Ser Ser Gly Tyr His Tyr Gly 
                85                  90                  95      


Val Ser Ala Cys Glu Gly Cys Lys Gly Phe Phe Arg Arg Ser Ile Gln 
            100                 105                 110         


Lys Asn Met Val Tyr Thr Cys His Arg Asp Lys Asn Cys Ile Ile Asn 
        115                 120                 125             


Lys Val Thr Arg Asn Arg Cys Gln Tyr Cys Arg Leu Gln Lys Cys Phe 
    130                 135                 140                 


Glu Val Gly Met Ser Lys Glu Ser Val Arg Asn Asp Arg Asn Lys Lys 
145                 150                 155                 160 


Lys Lys Glu Val Pro Lys Pro Glu Cys Ser Glu Ser Tyr Thr Leu Thr 
                165                 170                 175     


Pro Glu Val Gly Glu Leu Ile Glu Lys Val Arg Lys Ala His Gln Glu 
            180                 185                 190         


Thr Phe Pro Ala Leu Cys Gln Leu Gly Lys Tyr Thr Thr Asn Asn Ser 
        195                 200                 205             


Ser Glu Gln Arg Val Ser Leu Asp Ile Asp Leu Trp Asp Lys Phe Ser 
    210                 215                 220                 


Glu Leu Ser Thr Lys Cys Ile Ile Lys Thr Val Glu Phe Ala Lys Gln 
225                 230                 235                 240 


Leu Pro Gly Phe Thr Thr Leu Thr Ile Ala Asp Gln Ile Thr Leu Leu 
                245                 250                 255     


Lys Ala Ala Cys Leu Asp Ile Leu Ile Leu Arg Ile Cys Thr Arg Tyr 
            260                 265                 270         


Thr Pro Glu Gln Asp Thr Met Thr Phe Ser Asp Gly Leu Thr Leu Asn 
        275                 280                 285             


Arg Thr Gln Met His Asn Ala Gly Phe Gly Pro Leu Thr Asp Leu Val 
    290                 295                 300                 


Phe Ala Phe Ala Asn Gln Leu Leu Pro Leu Glu Met Asp Asp Ala Glu 
305                 310                 315                 320 


Thr Gly Leu Leu Ser Ala Ile Cys Leu Ile Cys Gly Asp Arg Gln Asp 
                325                 330                 335     


Leu Glu Gln Pro Asp Arg Val Asp Met Leu Gln Glu Pro Leu Leu Glu 
            340                 345                 350         


Ala Leu Lys Val Tyr Val Arg Lys Arg Arg Pro Ser Arg Pro His Met 
        355                 360                 365             


Phe Pro Lys Met Leu Met Lys Ile Thr Asp Leu Arg Ser Ile Ser Ala 
    370                 375                 380                 


Lys Gly Ala Glu Arg Val Ile Thr Leu Lys Met Glu Ile Pro Gly Ser 
385                 390                 395                 400 


Met Pro Pro Leu Ile Gln Glu Met Leu Glu Asn Ser Glu Gly Leu Asp 
                405                 410                 415     


Thr Leu Ser Gly Gln Pro Gly Gly Gly Gly Arg Asp Gly Gly Gly Leu 
            420                 425                 430         


Ala Pro Pro Pro Gly Ser Cys Ser Pro Ser Leu Ser Pro Ser Ser Asn 
        435                 440                 445             


Arg Ser Ser Pro Ala Thr His Ser Pro 
    450                 455         


<210>  3032
<211>  345
<212>  PRT
<213>  homo sapiens

<400>  3032

Met Gly Val Cys Gly Tyr Leu Phe Leu Pro Trp Lys Cys Leu Val Val 
1               5                   10                  15      


Val Ser Leu Arg Leu Leu Phe Leu Val Pro Thr Gly Val Pro Val Arg 
            20                  25                  30          


Ser Gly Asp Ala Thr Phe Pro Lys Ala Met Asp Asn Val Thr Val Arg 
        35                  40                  45              


Gln Gly Glu Ser Ala Thr Leu Arg Cys Thr Ile Asp Asp Arg Val Thr 
    50                  55                  60                  


Arg Val Ala Trp Leu Asn Arg Ser Thr Ile Leu Tyr Ala Gly Asn Asp 
65                  70                  75                  80  


Lys Trp Ser Ile Asp Pro Arg Val Ile Ile Leu Val Asn Thr Pro Thr 
                85                  90                  95      


Gln Tyr Ser Ile Met Ile Gln Asn Val Asp Val Tyr Asp Glu Gly Pro 
            100                 105                 110         


Tyr Thr Cys Ser Val Gln Thr Asp Asn His Pro Lys Thr Ser Arg Val 
        115                 120                 125             


His Leu Ile Val Gln Val Pro Pro Gln Ile Met Asn Ile Ser Ser Asp 
    130                 135                 140                 


Ile Thr Val Asn Glu Gly Ser Ser Val Thr Leu Leu Cys Leu Ala Ile 
145                 150                 155                 160 


Gly Arg Pro Glu Pro Thr Val Thr Trp Arg His Leu Ser Val Lys Glu 
                165                 170                 175     


Gly Gln Gly Phe Val Ser Glu Asp Glu Tyr Leu Glu Ile Ser Asp Ile 
            180                 185                 190         


Lys Arg Asp Gln Ser Gly Glu Tyr Glu Cys Ser Ala Leu Asn Asp Val 
        195                 200                 205             


Ala Ala Pro Asp Val Arg Lys Val Lys Ile Thr Val Asn Tyr Pro Pro 
    210                 215                 220                 


Tyr Ile Ser Lys Ala Lys Asn Thr Gly Val Ser Val Gly Gln Lys Gly 
225                 230                 235                 240 


Ile Leu Ser Cys Glu Ala Ser Ala Val Pro Met Ala Glu Phe Gln Trp 
                245                 250                 255     


Phe Lys Glu Glu Thr Arg Leu Ala Thr Gly Leu Asp Gly Met Arg Ile 
            260                 265                 270         


Glu Asn Lys Gly Arg Met Ser Thr Leu Thr Phe Phe Asn Val Ser Glu 
        275                 280                 285             


Lys Asp Tyr Gly Asn Tyr Thr Cys Val Ala Thr Asn Lys Leu Gly Asn 
    290                 295                 300                 


Thr Asn Ala Ser Ile Thr Leu Tyr Gly Pro Gly Ala Val Ile Asp Gly 
305                 310                 315                 320 


Val Asn Ser Ala Ser Arg Ala Leu Ala Cys Leu Trp Leu Ser Gly Thr 
                325                 330                 335     


Leu Leu Ala His Phe Phe Ile Lys Phe 
            340                 345 


<210>  3033
<211>  338
<212>  PRT
<213>  homo sapiens

<400>  3033

Met Tyr His Pro Ala Tyr Trp Val Val Phe Ser Ala Thr Thr Ala Leu 
1               5                   10                  15      


Leu Phe Ile Pro Gly Val Pro Val Arg Ser Gly Asp Ala Thr Phe Pro 
            20                  25                  30          


Lys Ala Met Asp Asn Val Thr Val Arg Gln Gly Glu Ser Ala Thr Leu 
        35                  40                  45              


Arg Cys Thr Ile Asp Asp Arg Val Thr Arg Val Ala Trp Leu Asn Arg 
    50                  55                  60                  


Ser Thr Ile Leu Tyr Ala Gly Asn Asp Lys Trp Ser Ile Asp Pro Arg 
65                  70                  75                  80  


Val Ile Ile Leu Val Asn Thr Pro Thr Gln Tyr Ser Ile Met Ile Gln 
                85                  90                  95      


Asn Val Asp Val Tyr Asp Glu Gly Pro Tyr Thr Cys Ser Val Gln Thr 
            100                 105                 110         


Asp Asn His Pro Lys Thr Ser Arg Val His Leu Ile Val Gln Val Pro 
        115                 120                 125             


Pro Gln Ile Met Asn Ile Ser Ser Asp Ile Thr Val Asn Glu Gly Ser 
    130                 135                 140                 


Ser Val Thr Leu Leu Cys Leu Ala Ile Gly Arg Pro Glu Pro Thr Val 
145                 150                 155                 160 


Thr Trp Arg His Leu Ser Val Lys Glu Gly Gln Gly Phe Val Ser Glu 
                165                 170                 175     


Asp Glu Tyr Leu Glu Ile Ser Asp Ile Lys Arg Asp Gln Ser Gly Glu 
            180                 185                 190         


Tyr Glu Cys Ser Ala Leu Asn Asp Val Ala Ala Pro Asp Val Arg Lys 
        195                 200                 205             


Val Lys Ile Thr Val Asn Tyr Pro Pro Tyr Ile Ser Lys Ala Lys Asn 
    210                 215                 220                 


Thr Gly Val Ser Val Gly Gln Lys Gly Ile Leu Ser Cys Glu Ala Ser 
225                 230                 235                 240 


Ala Val Pro Met Ala Glu Phe Gln Trp Phe Lys Glu Glu Thr Arg Leu 
                245                 250                 255     


Ala Thr Gly Leu Asp Gly Met Arg Ile Glu Asn Lys Gly Arg Met Ser 
            260                 265                 270         


Thr Leu Thr Phe Phe Asn Val Ser Glu Lys Asp Tyr Gly Asn Tyr Thr 
        275                 280                 285             


Cys Val Ala Thr Asn Lys Leu Gly Asn Thr Asn Ala Ser Ile Thr Leu 
    290                 295                 300                 


Tyr Gly Pro Gly Ala Val Ile Asp Gly Val Asn Ser Ala Ser Arg Ala 
305                 310                 315                 320 


Leu Ala Cys Leu Trp Leu Ser Gly Thr Leu Leu Ala His Phe Phe Ile 
                325                 330                 335     


Lys Phe 
        


<210>  3034
<211>  889
<212>  PRT
<213>  homo sapiens

<400>  3034

Met Glu Gly Gly Leu Ala Asp Gly Glu Pro Asp Arg Thr Ser Leu Leu 
1               5                   10                  15      


Gly Asp Ser Lys Asp Val Leu Gly Pro Ser Thr Val Val Ala Asn Ser 
            20                  25                  30          


Asp Glu Ser Gln Leu Leu Thr Pro Gly Lys Met Ser Gln Arg Gln Gly 
        35                  40                  45              


Lys Glu Ala Tyr Pro Thr Pro Thr Lys Asp Leu His Gln Pro Ser Leu 
    50                  55                  60                  


Ser Pro Ala Ser Pro His Ser Gln Gly Phe Glu Arg Gly Lys Glu Asp 
65                  70                  75                  80  


Ile Ser Gln Asn Lys Asp Glu Ser Ser Leu Ser Met Ser Lys Ser Lys 
                85                  90                  95      


Ser Glu Ser Lys Leu Tyr Asn Gly Ser Glu Lys Asp Ser Ser Thr Ser 
            100                 105                 110         


Ser Lys Leu Thr Lys Lys Glu Ser Leu Lys Val Gln Lys Lys Asn Tyr 
        115                 120                 125             


Arg Glu Glu Lys Lys Arg Ala Thr Lys Glu Leu Leu Ser Thr Ile Thr 
    130                 135                 140                 


Asp Pro Ser Val Ile Val Met Ala Asp Trp Leu Lys Ile Arg Gly Thr 
145                 150                 155                 160 


Leu Lys Ser Trp Thr Lys Leu Trp Cys Val Leu Lys Pro Gly Val Leu 
                165                 170                 175     


Leu Ile Tyr Lys Thr Gln Lys Asn Gly Gln Trp Val Gly Thr Val Leu 
            180                 185                 190         


Leu Asn Ala Cys Glu Ile Ile Glu Arg Pro Ser Lys Lys Asp Gly Phe 
        195                 200                 205             


Cys Phe Lys Leu Phe His Pro Leu Glu Gln Ser Ile Trp Ala Val Lys 
    210                 215                 220                 


Gly Pro Lys Gly Glu Ala Val Gly Ser Ile Thr Gln Pro Leu Pro Ser 
225                 230                 235                 240 


Ser Tyr Leu Ile Ile Arg Ala Thr Ser Glu Ser Asp Gly Arg Cys Trp 
                245                 250                 255     


Met Asp Ala Leu Glu Leu Ala Leu Lys Cys Ser Ser Leu Leu Lys Arg 
            260                 265                 270         


Thr Met Ile Arg Glu Gly Lys Glu His Asp Leu Ser Val Ser Ser Asp 
        275                 280                 285             


Ser Thr His Val Thr Phe Tyr Gly Leu Leu Arg Ala Asn Asn Leu His 
    290                 295                 300                 


Ser Gly Asp Asn Phe Gln Leu Asn Asp Ser Glu Ile Glu Arg Gln His 
305                 310                 315                 320 


Phe Lys Asp Gln Asp Met Tyr Ser Asp Lys Ser Asp Lys Glu Asn Asp 
                325                 330                 335     


Gln Glu His Asp Glu Ser Asp Asn Glu Val Met Gly Lys Ser Glu Glu 
            340                 345                 350         


Ser Asp Thr Asp Thr Ser Glu Arg Gln Asp Asp Ser Tyr Ile Glu Pro 
        355                 360                 365             


Glu Pro Val Glu Pro Leu Lys Glu Thr Thr Tyr Thr Glu Gln Ser His 
    370                 375                 380                 


Glu Glu Leu Gly Glu Ala Gly Glu Ala Ser Gln Thr Glu Thr Val Ser 
385                 390                 395                 400 


Glu Glu Asn Lys Ser Leu Ile Trp Thr Leu Leu Lys Gln Val Arg Pro 
                405                 410                 415     


Gly Met Asp Leu Ser Lys Val Val Leu Pro Thr Phe Ile Leu Glu Pro 
            420                 425                 430         


Arg Ser Phe Leu Asp Lys Leu Ser Asp Tyr Tyr Tyr His Ala Asp Phe 
        435                 440                 445             


Leu Ser Glu Ala Ala Leu Glu Glu Asn Pro Tyr Phe Arg Leu Lys Lys 
    450                 455                 460                 


Val Val Lys Trp Tyr Leu Ser Gly Phe Tyr Lys Lys Pro Lys Gly Leu 
465                 470                 475                 480 


Lys Lys Pro Tyr Asn Pro Ile Leu Gly Glu Thr Phe Arg Cys Leu Trp 
                485                 490                 495     


Ile His Pro Arg Thr Asn Ser Lys Thr Phe Tyr Ile Ala Glu Gln Val 
            500                 505                 510         


Ser His His Pro Pro Ile Ser Ala Phe Tyr Val Ser Asn Arg Lys Asp 
        515                 520                 525             


Gly Phe Cys Leu Ser Gly Ser Ile Leu Ala Lys Ser Lys Phe Tyr Gly 
    530                 535                 540                 


Asn Ser Leu Ser Ala Ile Leu Glu Gly Glu Ala Arg Leu Thr Phe Leu 
545                 550                 555                 560 


Asn Arg Gly Glu Asp Tyr Val Met Thr Met Pro Tyr Ala His Cys Lys 
                565                 570                 575     


Gly Ile Leu Tyr Gly Thr Met Thr Leu Glu Leu Gly Gly Thr Val Asn 
            580                 585                 590         


Ile Thr Cys Gln Lys Thr Gly Tyr Ser Ala Ile Leu Glu Phe Lys Leu 
        595                 600                 605             


Lys Pro Phe Leu Gly Ser Ser Asp Cys Val Asn Gln Ile Ser Gly Lys 
    610                 615                 620                 


Leu Lys Leu Gly Lys Glu Val Leu Ala Thr Leu Glu Gly His Trp Asp 
625                 630                 635                 640 


Ser Glu Val Phe Ile Thr Asp Lys Lys Thr Asp Asn Ser Glu Val Phe 
                645                 650                 655     


Trp Asn Pro Thr Pro Asp Ile Lys Gln Trp Arg Leu Ile Arg His Thr 
            660                 665                 670         


Val Lys Phe Glu Glu Gln Gly Asp Phe Glu Ser Glu Lys Leu Trp Gln 
        675                 680                 685             


Arg Val Thr Arg Ala Ile Asn Ala Lys Asp Gln Thr Glu Ala Thr Gln 
    690                 695                 700                 


Glu Lys Tyr Val Leu Glu Glu Ala Gln Arg Gln Ala Ala Arg Asp Arg 
705                 710                 715                 720 


Lys Thr Lys Asn Glu Glu Trp Ser Cys Lys Leu Phe Glu Leu Asp Pro 
                725                 730                 735     


Leu Thr Gly Glu Trp His Tyr Lys Phe Ala Asp Thr Arg Pro Trp Asp 
            740                 745                 750         


Pro Leu Asn Asp Met Ile Gln Phe Glu Lys Asp Gly Val Ile Gln Thr 
        755                 760                 765             


Lys Val Lys His Arg Thr Pro Met Val Ser Val Pro Lys Met Lys His 
    770                 775                 780                 


Lys Pro Thr Arg Gln Gln Lys Lys Val Ala Lys Gly Tyr Ser Ser Pro 
785                 790                 795                 800 


Glu Pro Asp Ile Gln Asp Ser Ser Gly Ser Glu Ala Gln Ser Val Lys 
                805                 810                 815     


Pro Ser Thr Arg Arg Lys Lys Gly Ile Glu Leu Gly Asp Ile Gln Ser 
            820                 825                 830         


Ser Ile Glu Ser Ile Lys Gln Thr Gln Glu Glu Ile Lys Arg Asn Ile 
        835                 840                 845             


Met Ala Leu Arg Asn His Leu Val Ser Ser Thr Pro Ala Thr Asp Tyr 
    850                 855                 860                 


Phe Leu Gln Gln Lys Asp Tyr Phe Ile Ile Phe Leu Leu Ile Leu Leu 
865                 870                 875                 880 


Gln Val Ile Ile Asn Phe Met Phe Lys 
                885                 


<210>  3035
<211>  911
<212>  PRT
<213>  homo sapiens

<400>  3035

Met Glu Val Asn Cys Leu Thr Leu Lys Asp Leu Ile Ser Pro Arg Gln 
1               5                   10                  15      


Pro Arg Leu Asp Phe Ala Val Glu Asp Gly Glu Asn Ala Gln Lys Glu 
            20                  25                  30          


Asn Ile Phe Val Asp Arg Ser Arg Met Ala Pro Lys Thr Pro Ile Lys 
        35                  40                  45              


Asn Glu Pro Ile Asp Leu Ser Lys Gln Lys Lys Phe Thr Pro Glu Arg 
    50                  55                  60                  


Asn Pro Ile Thr Pro Val Lys Phe Val Asp Arg Gln Gln Ala Glu Pro 
65                  70                  75                  80  


Trp Thr Pro Thr Ala Asn Leu Lys Met Leu Ile Ser Ala Ala Ser Pro 
                85                  90                  95      


Asp Ile Arg Asp Arg Glu Lys Lys Lys Gly Leu Phe Arg Pro Ile Glu 
            100                 105                 110         


Asn Lys Asp Asp Ala Phe Thr Asp Ser Leu Gln Leu Asp Val Val Gly 
        115                 120                 125             


Asp Ser Ala Val Asp Glu Phe Glu Lys Gln Arg Pro Ser Arg Lys Gln 
    130                 135                 140                 


Lys Ser Leu Gly Leu Leu Cys Gln Lys Phe Leu Ala Arg Tyr Pro Ser 
145                 150                 155                 160 


Tyr Pro Leu Ser Thr Glu Lys Thr Thr Ile Ser Leu Asp Glu Val Ala 
                165                 170                 175     


Val Ser Leu Gly Val Glu Arg Arg Arg Ile Tyr Asp Ile Val Asn Val 
            180                 185                 190         


Leu Glu Ser Leu His Leu Val Ser Arg Val Ala Lys Asn Gln Tyr Gly 
        195                 200                 205             


Trp His Gly Arg His Ser Leu Pro Lys Thr Leu Arg Asn Leu Gln Arg 
    210                 215                 220                 


Leu Gly Glu Glu Gln Lys Tyr Glu Glu Gln Met Ala Tyr Leu Gln Gln 
225                 230                 235                 240 


Lys Glu Leu Asp Leu Ile Asp Tyr Lys Phe Gly Glu Arg Lys Lys Asp 
                245                 250                 255     


Gly Asp Pro Asp Ser Gln Glu Gln Gln Leu Leu Asp Phe Ser Glu Pro 
            260                 265                 270         


Asp Cys Pro Ser Ser Ser Ala Asn Ser Arg Lys Asp Lys Ser Leu Arg 
        275                 280                 285             


Ile Met Ser Gln Lys Phe Val Met Leu Phe Leu Val Ser Lys Thr Lys 
    290                 295                 300                 


Ile Val Thr Leu Asp Val Ala Ala Lys Ile Leu Ile Glu Glu Ser Gln 
305                 310                 315                 320 


Asp Ala Pro Asp His Ser Lys Phe Lys Thr Lys Val Arg Arg Leu Tyr 
                325                 330                 335     


Asp Ile Ala Asn Val Leu Thr Ser Leu Ala Leu Ile Lys Lys Val His 
            340                 345                 350         


Val Thr Glu Glu Arg Gly Arg Lys Pro Ala Phe Lys Trp Ile Gly Pro 
        355                 360                 365             


Val Asp Phe Ser Ser Ser Asp Glu Glu Leu Val Asp Val Ser Ala Ser 
    370                 375                 380                 


Val Leu Pro Glu Leu Lys Arg Glu Thr Tyr Gly Gln Ile Gln Val Cys 
385                 390                 395                 400 


Ala Lys Gln Lys Leu Ala Arg His Gly Ser Phe Asn Thr Val Gln Ala 
                405                 410                 415     


Ser Glu Arg Ile Gln Arg Lys Val Asn Ser Glu Pro Ser Ser Pro Tyr 
            420                 425                 430         


Arg Glu Glu Gln Gly Ser Gly Gly Tyr Ser Leu Glu Ile Gly Ser Leu 
        435                 440                 445             


Ala Ala Val Tyr Arg Gln Lys Ile Glu Asp Asn Ser Gln Gly Lys Ala 
    450                 455                 460                 


Phe Ala Ser Lys Arg Val Val Pro Pro Ser Ser Ser Leu Asp Pro Val 
465                 470                 475                 480 


Ala Pro Phe Pro Val Leu Ser Val Asp Pro Glu Tyr Cys Val Asn Pro 
                485                 490                 495     


Leu Ala His Pro Val Phe Ser Val Ala Gln Thr Asp Leu Gln Ala Phe 
            500                 505                 510         


Ser Met Gln Asn Gly Leu Asn Gly Gln Val Asp Val Ser Leu Ala Ser 
        515                 520                 525             


Ala Ala Ser Ala Val Glu Ser Leu Lys Pro Ala Leu Leu Ala Gly Gln 
    530                 535                 540                 


Pro Leu Val Tyr Val Pro Ser Ala Ser Leu Phe Met Leu Tyr Gly Ser 
545                 550                 555                 560 


Leu Gln Glu Gly Pro Ala Ser Gly Ser Gly Ser Glu Arg Asp Asp Arg 
                565                 570                 575     


Ser Ser Glu Ala Pro Ala Thr Val Glu Leu Ser Ser Ala Pro Ser Ala 
            580                 585                 590         


Gln Lys Arg Leu Cys Glu Glu Arg Lys Pro Gln Glu Glu Asp Glu Pro 
        595                 600                 605             


Ala Thr Lys Arg Gln Ser Arg Glu Tyr Glu Asp Gly Pro Leu Ser Leu 
    610                 615                 620                 


Val Met Pro Lys Lys Pro Ser Asp Ser Thr Asp Leu Ala Ser Pro Lys 
625                 630                 635                 640 


Thr Met Gly Asn Arg Ala Ser Ile Pro Leu Lys Asp Ile His Val Asn 
                645                 650                 655     


Gly Gln Leu Pro Ala Ala Glu Glu Ile Ser Gly Lys Ala Thr Ala Asn 
            660                 665                 670         


Ser Leu Val Ser Ser Glu Trp Gly Asn Pro Ser Arg Asn Thr Asp Val 
        675                 680                 685             


Glu Lys Pro Ser Lys Glu Asn Glu Ser Thr Lys Glu Pro Ser Leu Leu 
    690                 695                 700                 


Gln Tyr Leu Cys Val Gln Ser Pro Ala Gly Leu Asn Gly Phe Asn Val 
705                 710                 715                 720 


Leu Leu Ser Gly Ser Gln Thr Pro Pro Thr Val Gly Pro Ser Ser Gly 
                725                 730                 735     


Gln Leu Pro Ser Phe Ser Val Pro Cys Met Val Leu Pro Ser Pro Pro 
            740                 745                 750         


Leu Gly Pro Phe Pro Val Leu Tyr Ser Pro Ala Met Pro Gly Pro Val 
        755                 760                 765             


Ser Ser Thr Leu Gly Ala Leu Pro Asn Thr Gly Pro Val Asn Phe Ser 
    770                 775                 780                 


Leu Pro Gly Leu Gly Ser Ile Ala Gln Leu Leu Val Gly Pro Thr Ala 
785                 790                 795                 800 


Val Val Asn Pro Lys Ser Ser Thr Leu Pro Ser Ala Asp Pro Gln Leu 
                805                 810                 815     


Gln Ser Gln Pro Ser Leu Asn Leu Ser Pro Val Met Ser Arg Ser His 
            820                 825                 830         


Ser Val Val Gln Gln Pro Glu Ser Pro Val Tyr Val Gly His Pro Val 
        835                 840                 845             


Ser Val Val Lys Leu His Gln Ser Pro Val Pro Val Thr Pro Lys Ser 
    850                 855                 860                 


Ile Gln Arg Thr His Arg Glu Thr Phe Phe Lys Thr Pro Gly Ser Leu 
865                 870                 875                 880 


Gly Asp Pro Val Leu Lys Arg Arg Glu Arg Asn Gln Ser Arg Asn Thr 
                885                 890                 895     


Ser Ser Ala Gln Arg Arg Leu Glu Ile Pro Ser Gly Gly Ala Asp 
            900                 905                 910     


<210>  3036
<211>  784
<212>  PRT
<213>  homo sapiens

<400>  3036

Met Glu Gly Ala Met Ala Val Arg Val Thr Ala Ala His Thr Ala Glu 
1               5                   10                  15      


Ala Gln Ala Glu Ala Gly Arg Glu Ala Gly Glu Gly Ala Val Ala Ala 
            20                  25                  30          


Val Ala Ala Ala Leu Ala Pro Ser Gly Phe Leu Gly Leu Pro Ala Pro 
        35                  40                  45              


Phe Ser Glu Glu Asp Glu Asp Asp Val His Arg Cys Gly Arg Cys Gln 
    50                  55                  60                  


Ala Glu Phe Thr Ala Leu Glu Asp Phe Val Gln His Lys Ile Gln Lys 
65                  70                  75                  80  


Ala Cys Gln Arg Ala Pro Pro Glu Ala Leu Pro Ala Thr Pro Ala Thr 
                85                  90                  95      


Thr Ala Leu Leu Gly Gln Glu Val Val Pro Ala Ala Pro Gly Pro Glu 
            100                 105                 110         


Glu Pro Ile Thr Val Ala His Ile Val Val Glu Ala Ala Ser Leu Ala 
        115                 120                 125             


Ala Asp Ile Ser His Ala Ser Asp Leu Val Gly Gly Gly His Ile Lys 
    130                 135                 140                 


Glu Val Ile Val Ala Ala Glu Ala Glu Leu Gly Asp Gly Glu Met Ala 
145                 150                 155                 160 


Glu Ala Pro Gly Ser Pro His Gln Gln Gly Leu Gly Leu Ala Gly Glu 
                165                 170                 175     


Gly Glu Gln Ala Gln Val Lys Leu Leu Val Asn Lys Asp Gly Arg Tyr 
            180                 185                 190         


Val Cys Ala Leu Cys His Lys Thr Phe Lys Thr Gly Ser Ile Leu Lys 
        195                 200                 205             


Ala His Met Val Thr His Ser Ser Arg Lys Asp His Glu Cys Lys Leu 
    210                 215                 220                 


Cys Gly Ala Ser Phe Arg Thr Lys Gly Ser Leu Ile Arg His His Arg 
225                 230                 235                 240 


Arg His Thr Asp Glu Arg Pro Tyr Lys Cys Ser Lys Cys Gly Lys Ser 
                245                 250                 255     


Phe Arg Glu Ser Gly Ala Leu Thr Arg His Leu Lys Ser Leu Thr Pro 
            260                 265                 270         


Cys Thr Glu Lys Ile Arg Phe Ser Val Ser Lys Asp Val Val Val Ser 
        275                 280                 285             


Lys Glu Asp Ala Arg Ala Gly Ser Gly Ala Gly Ala Ala Gly Leu Gly 
    290                 295                 300                 


Thr Ala Thr Ser Ser Val Thr Gly Glu Pro Ile Glu Thr Ser Pro Val 
305                 310                 315                 320 


Ile His Leu Val Thr Asp Ala Lys Gly Thr Val Ile His Glu Val His 
                325                 330                 335     


Val Gln Met Gln Glu Leu Ser Leu Gly Met Lys Ala Leu Ala Pro Glu 
            340                 345                 350         


Pro Pro Val Ser Gln Glu Leu Pro Cys Ser Ser Glu Gly Ser Arg Glu 
        355                 360                 365             


Asn Leu Leu His Gln Ala Met Gln Asn Ser Gly Ile Val Leu Glu Arg 
    370                 375                 380                 


Ala Ala Gly Glu Glu Gly Ala Leu Glu Pro Ala Pro Ala Ala Gly Ser 
385                 390                 395                 400 


Ser Pro Gln Pro Leu Ala Val Ala Ala Pro Gln Leu Pro Val Leu Glu 
                405                 410                 415     


Val Gln Pro Leu Glu Thr Gln Val Ala Ser Glu Ala Ser Ala Val Pro 
            420                 425                 430         


Arg Thr His Pro Cys Pro Gln Cys Ser Glu Thr Phe Pro Thr Ala Ala 
        435                 440                 445             


Thr Leu Glu Ala His Lys Arg Gly His Thr Gly Pro Arg Pro Phe Ala 
    450                 455                 460                 


Cys Ala Gln Cys Gly Lys Ala Phe Pro Lys Ala Tyr Leu Leu Lys Lys 
465                 470                 475                 480 


His Gln Glu Val His Val Arg Glu Arg Arg Phe Arg Cys Gly Asp Cys 
                485                 490                 495     


Gly Lys Leu Tyr Lys Thr Ile Ala His Val Arg Gly His Arg Arg Val 
            500                 505                 510         


His Ser Asp Glu Arg Pro Tyr Pro Cys Pro Lys Cys Gly Lys Arg Tyr 
        515                 520                 525             


Lys Thr Lys Asn Ala Gln Gln Val His Phe Arg Thr His Leu Glu Glu 
    530                 535                 540                 


Lys Pro His Val Cys Gln Phe Cys Ser Arg Gly Phe Arg Glu Lys Gly 
545                 550                 555                 560 


Ser Leu Val Arg His Val Arg His His Thr Gly Glu Lys Pro Phe Lys 
                565                 570                 575     


Cys Tyr Lys Cys Gly Arg Gly Phe Ala Glu His Gly Thr Leu Asn Arg 
            580                 585                 590         


His Leu Arg Thr Lys Gly Gly Cys Leu Leu Glu Val Glu Glu Leu Leu 
        595                 600                 605             


Val Ser Glu Asp Ser Pro Ala Ala Ala Thr Thr Val Leu Thr Glu Asp 
    610                 615                 620                 


Pro His Thr Val Leu Val Glu Phe Ser Ser Val Val Ala Asp Thr Gln 
625                 630                 635                 640 


Glu Tyr Ile Ile Glu Ala Thr Ala Asp Asp Ala Glu Thr Ser Glu Ala 
                645                 650                 655     


Thr Glu Ile Ile Glu Gly Thr Gln Thr Glu Val Asp Ser His Ile Met 
            660                 665                 670         


Lys Val Val Gln Gln Ile Val His Gln Ala Ser Ala Gly His Gln Ile 
        675                 680                 685             


Ile Val Gln Asn Val Thr Met Asp Glu Glu Thr Ala Leu Gly Pro Glu 
    690                 695                 700                 


Ala Ala Ala Ala Asp Thr Ile Thr Ile Ala Thr Pro Glu Ser Leu Thr 
705                 710                 715                 720 


Glu Gln Val Ala Met Thr Leu Ala Ser Ala Ile Ser Glu Gly Thr Val 
                725                 730                 735     


Leu Ala Ala Arg Ala Gly Thr Ser Gly Thr Glu Gln Ala Thr Val Thr 
            740                 745                 750         


Met Val Ser Ser Glu Asp Ile Glu Ile Leu Glu His Ala Gly Glu Leu 
        755                 760                 765             


Val Ile Ala Ser Pro Glu Gly Gln Leu Glu Val Gln Thr Val Ile Val 
    770                 775                 780                 


<210>  3037
<211>  606
<212>  PRT
<213>  homo sapiens

<400>  3037

Met Ser His Thr Ala Ser Ser Cys Gln Glu Leu Val Glu Asn Cys Ala 
1               5                   10                  15      


Val His Val Ala Gly Met Ala Gln Glu Asp Ser Arg Arg Gly Gln Val 
            20                  25                  30          


Pro Ser Ser Phe Tyr His Gly Ala Asn Gln Glu Leu Asp Leu Ser Thr 
        35                  40                  45              


Lys Val Tyr Lys Arg Glu Ser Gly Ser Pro Tyr Ser Val Leu Val Asp 
    50                  55                  60                  


Thr Lys Met Ser Lys Pro His Leu His Glu Thr Glu Glu Gln Pro Tyr 
65                  70                  75                  80  


Phe Arg Glu Thr Arg Ala Val Ser Asp Val His Ala Val Lys Glu Asp 
                85                  90                  95      


Arg Glu Asn Ser Asp Asp Thr Glu Glu Glu Glu Glu Glu Val Ser Tyr 
            100                 105                 110         


Lys Arg Glu Gln Ile Ile Val Glu Val Asn Leu Asn Asn Gln Thr Leu 
        115                 120                 125             


Asn Val Ser Lys Gly Glu Lys Gly Val Ser Ser Gln Ser Lys Glu Thr 
    130                 135                 140                 


Pro Val Leu Lys Thr Ser Ser Glu Glu Glu Glu Glu Glu Ser Glu Glu 
145                 150                 155                 160 


Glu Ala Thr Asp Asp Ser Asn Asp Tyr Gly Glu Asn Glu Lys Gln Lys 
                165                 170                 175     


Lys Lys Glu Lys Ile Val Glu Lys Val Ser Val Thr Gln Arg Arg Thr 
            180                 185                 190         


Arg Arg Ala Ala Ser Val Ala Ala Ala Thr Thr Ser Pro Thr Pro Arg 
        195                 200                 205             


Thr Thr Arg Gly Arg Arg Lys Ser Val Glu Pro Pro Lys Arg Lys Lys 
    210                 215                 220                 


Arg Ala Thr Lys Glu Pro Lys Ala Pro Val Gln Lys Ala Lys Cys Glu 
225                 230                 235                 240 


Glu Lys Glu Thr Leu Thr Cys Glu Lys Cys Pro Arg Val Phe Asn Thr 
                245                 250                 255     


Arg Trp Tyr Leu Glu Lys His Met Asn Val Thr His Arg Arg Met Gln 
            260                 265                 270         


Ile Cys Asp Lys Cys Gly Lys Lys Phe Val Leu Glu Ser Glu Leu Ser 
        275                 280                 285             


Leu His Gln Gln Thr Asp Cys Glu Lys Asn Ile Gln Cys Val Ser Cys 
    290                 295                 300                 


Asn Lys Ser Phe Lys Lys Leu Trp Ser Leu His Glu His Ile Lys Ile 
305                 310                 315                 320 


Val His Gly Tyr Ala Glu Lys Lys Phe Ser Cys Glu Ile Cys Glu Lys 
                325                 330                 335     


Lys Phe Tyr Thr Met Ala His Val Arg Lys His Met Val Ala His Thr 
            340                 345                 350         


Lys Asp Met Pro Phe Thr Cys Glu Thr Cys Gly Lys Ser Phe Lys Arg 
        355                 360                 365             


Ser Met Ser Leu Lys Val His Ser Leu Gln His Ser Gly Glu Lys Pro 
    370                 375                 380                 


Phe Arg Cys Glu Asn Cys Asp Glu Arg Phe Gln Tyr Lys Tyr Gln Leu 
385                 390                 395                 400 


Arg Ser His Met Ser Ile His Ile Gly His Lys Gln Phe Met Cys Gln 
                405                 410                 415     


Trp Cys Gly Lys Asp Phe Asn Met Lys Gln Tyr Phe Asp Glu His Met 
            420                 425                 430         


Lys Thr His Thr Gly Glu Lys Pro Phe Ile Cys Glu Ile Cys Gly Lys 
        435                 440                 445             


Ser Phe Thr Ser Arg Pro Asn Met Lys Arg His Arg Arg Thr His Thr 
    450                 455                 460                 


Gly Glu Lys Pro Tyr Pro Cys Asp Val Cys Gly Gln Arg Phe Arg Phe 
465                 470                 475                 480 


Ser Asn Met Leu Lys Ala His Lys Glu Lys Cys Phe Arg Val Thr Ser 
                485                 490                 495     


Pro Val Asn Val Pro Pro Ala Val Gln Ile Pro Leu Thr Thr Ser Pro 
            500                 505                 510         


Ala Thr Pro Val Pro Ser Val Val Asn Thr Ala Thr Thr Pro Thr Pro 
        515                 520                 525             


Pro Ile Asn Met Asn Pro Val Ser Thr Leu Pro Pro Arg Pro Ile Pro 
    530                 535                 540                 


His Pro Phe Ser His Leu His Ile His Pro His Pro His His Pro His 
545                 550                 555                 560 


His Leu Pro Ile Pro Pro Val Pro His Leu Pro Pro Pro Pro Ala Leu 
                565                 570                 575     


Phe Lys Ser Glu Pro Leu Asn His Arg Gly Gln Ser Glu Asp Asn Phe 
            580                 585                 590         


Leu Arg His Leu Ala Glu Lys Asn Ser Ser Ala Gln His His 
        595                 600                 605     


<210>  3038
<211>  406
<212>  PRT
<213>  homo sapiens

<400>  3038

Met Gly Lys Val Trp Lys Gln Gln Met Tyr Pro Gln Tyr Ala Thr Tyr 
1               5                   10                  15      


Tyr Tyr Pro Gln Tyr Leu Gln Ala Lys Gln Ser Leu Val Pro Ala His 
            20                  25                  30          


Pro Met Ala Pro Pro Ser Pro Ser Thr Thr Ser Ser Asn Asn Asn Ser 
        35                  40                  45              


Ser Ser Ser Ser Asn Ser Gly Trp Asp Gln Leu Ser Lys Thr Asn Leu 
    50                  55                  60                  


Tyr Ile Arg Gly Leu Pro Pro His Thr Thr Asp Gln Asp Leu Val Lys 
65                  70                  75                  80  


Leu Cys Gln Pro Tyr Gly Lys Ile Val Ser Thr Lys Ala Ile Leu Asp 
                85                  90                  95      


Lys Thr Thr Asn Lys Cys Lys Gly Tyr Gly Phe Val Asp Phe Asp Ser 
            100                 105                 110         


Pro Ala Ala Ala Gln Lys Ala Val Ser Ala Leu Lys Ala Ser Gly Val 
        115                 120                 125             


Gln Ala Gln Met Ala Lys Gln Gln Glu Gln Asp Pro Thr Asn Leu Tyr 
    130                 135                 140                 


Ile Ser Asn Leu Pro Leu Ser Met Asp Glu Gln Glu Leu Glu Asn Met 
145                 150                 155                 160 


Leu Lys Pro Phe Gly Gln Val Ile Ser Thr Arg Ile Leu Arg Asp Ser 
                165                 170                 175     


Ser Gly Thr Ser Arg Gly Val Gly Phe Ala Arg Met Glu Ser Thr Glu 
            180                 185                 190         


Lys Cys Glu Ala Val Ile Gly His Phe Asn Gly Lys Phe Ile Lys Thr 
        195                 200                 205             


Pro Pro Gly Val Ser Ala Pro Thr Glu Pro Leu Leu Cys Lys Phe Ala 
    210                 215                 220                 


Asp Gly Gly Gln Lys Lys Arg Gln Asn Pro Asn Lys Tyr Ile Pro Asn 
225                 230                 235                 240 


Gly Arg Pro Trp His Arg Glu Gly Glu Val Arg Leu Ala Gly Met Thr 
                245                 250                 255     


Leu Thr Tyr Asp Pro Thr Thr Ala Ala Ile Gln Asn Gly Phe Tyr Pro 
            260                 265                 270         


Ser Pro Tyr Ser Ile Ala Thr Asn Arg Met Ile Thr Gln Thr Ser Ile 
        275                 280                 285             


Thr Pro Tyr Ile Ala Ser Pro Val Ser Ala Tyr Gln Val Gln Ser Pro 
    290                 295                 300                 


Ser Trp Met Gln Pro Gln Pro Tyr Ile Leu Gln His Pro Gly Ala Val 
305                 310                 315                 320 


Leu Thr Pro Ser Met Glu His Thr Met Ser Leu Gln Pro Ala Ser Met 
                325                 330                 335     


Ile Ser Pro Leu Ala Gln Gln Met Ser His Leu Ser Leu Gly Ser Thr 
            340                 345                 350         


Gly Thr Tyr Met Pro Ala Thr Ser Ala Met Gln Gly Ala Tyr Leu Pro 
        355                 360                 365             


Gln Tyr Ala His Met Gln Thr Thr Ala Val Pro Val Glu Glu Ala Ser 
    370                 375                 380                 


Gly Gln Gln Gln Val Ala Val Glu Thr Ser Asn Asp His Ser Pro Tyr 
385                 390                 395                 400 


Thr Phe Gln Pro Asn Lys 
                405     


<210>  3039
<211>  930
<212>  PRT
<213>  homo sapiens

<400>  3039

Met Asn Gly Arg Ser Cys Ser Met Ser Leu His Arg Thr Ser Gly Thr 
1               5                   10                  15      


Pro Gln Gly Pro Arg Met Val Ser Gly His His Ile Pro Ala Ile Arg 
            20                  25                  30          


Ala His Ser Gly Thr Pro Gly Pro Ser Pro Cys Gly Ser Thr Ser Ser 
        35                  40                  45              


Pro Thr Met Ala Ser Leu Ala Asn Asn Leu His Leu Lys Met Pro Ser 
    50                  55                  60                  


Gly Gly Gly Met Ala Pro Gln Asn Asn Val Ala Glu Ser Arg Ile His 
65                  70                  75                  80  


Leu Pro Ala Leu Ser Pro Arg Arg Gln Met Leu Thr Asn Gly Lys Pro 
                85                  90                  95      


Arg Phe Gln Val Thr Gln Ala Gly Gly Met Ser Gly Ser His Thr Leu 
            100                 105                 110         


Lys Pro Lys Gln Gln Glu Phe Gly Ser Pro Phe Pro Pro Asn Pro Gly 
        115                 120                 125             


Lys Gly Ala Leu Gly Phe Gly Pro Gln Cys Lys Ser Ile Gly Lys Gly 
    130                 135                 140                 


Ser Cys Asn Asn Leu Val Val Thr Ser Ser Pro Met Met Val Gln Arg 
145                 150                 155                 160 


Leu Gly Leu Ile Ser Pro Pro Ala Ser Gln Val Ser Thr Ala Cys Asn 
                165                 170                 175     


Gln Ile Ser Pro Ser Leu Gln Arg Ala Met Asn Ala Ala Asn Leu Asn 
            180                 185                 190         


Ile Pro Pro Ser Asp Thr Arg Ser Leu Ile Ser Arg Glu Ser Leu Ala 
        195                 200                 205             


Ser Thr Thr Leu Ser Leu Thr Glu Ser Gln Ser Ala Ser Ser Met Lys 
    210                 215                 220                 


Gln Glu Trp Ser Gln Gly Tyr Arg Ala Leu Pro Ser Leu Ser Asn His 
225                 230                 235                 240 


Gly Ser Gln Asn Gly Leu Asp Leu Gly Asp Leu Leu Ser Leu Pro Pro 
                245                 250                 255     


Gly Thr Ser Met Ser Ser Asn Ser Val Ser Asn Ser Leu Pro Ser Tyr 
            260                 265                 270         


Leu Phe Gly Thr Glu Ser Ser His Ser Pro Tyr Pro Ser Pro Arg His 
        275                 280                 285             


Ser Ser Thr Arg Ser His Ser Ala Arg Ser Lys Lys Arg Ala Leu Ser 
    290                 295                 300                 


Leu Ser Pro Leu Ser Asp Gly Ile Gly Ile Asp Phe Asn Thr Ile Ile 
305                 310                 315                 320 


Arg Thr Ser Pro Thr Ser Leu Val Ala Tyr Ile Asn Gly Ser Arg Ala 
                325                 330                 335     


Ser Pro Ala Asn Leu Ser Pro Gln Pro Glu Val Tyr Gly His Phe Leu 
            340                 345                 350         


Gly Val Arg Gly Ser Cys Ile Pro Gln Pro Arg Pro Val Pro Gly Ser 
        355                 360                 365             


Gln Lys Gly Val Leu Val Ala Pro Gly Gly Leu Ala Leu Pro Ala Tyr 
    370                 375                 380                 


Gly Glu Asp Gly Ala Leu Glu His Glu Arg Met Gln Gln Leu Glu His 
385                 390                 395                 400 


Gly Gly Leu Gln Pro Gly Leu Val Asn His Met Val Val Gln His Gly 
                405                 410                 415     


Leu Pro Gly Pro Asp Ser Gln Ser Ala Gly Leu Phe Lys Thr Glu Arg 
            420                 425                 430         


Leu Glu Glu Phe Pro Gly Ser Thr Val Asp Leu Pro Pro Ala Pro Pro 
        435                 440                 445             


Leu Pro Pro Leu Pro Pro Pro Pro Gly Pro Pro Pro Pro Tyr His Ala 
    450                 455                 460                 


His Ala His Leu His His Pro Glu Leu Gly Pro His Ala Gln Gln Leu 
465                 470                 475                 480 


Ala Leu Pro Gln Ala Thr Leu Asp Asp Asp Gly Glu Met Asp Gly Ile 
                485                 490                 495     


Gly Gly Lys His Cys Cys Arg Trp Ile Asp Cys Ser Ala Leu Tyr Asp 
            500                 505                 510         


Gln Gln Glu Glu Leu Val Arg His Ile Glu Lys Val His Ile Asp Gln 
        515                 520                 525             


Arg Lys Gly Glu Asp Phe Thr Cys Phe Trp Ala Gly Cys Pro Arg Arg 
    530                 535                 540                 


Tyr Lys Pro Phe Asn Ala Arg Tyr Lys Leu Leu Ile His Met Arg Val 
545                 550                 555                 560 


His Ser Gly Glu Lys Pro Asn Lys Cys Thr Phe Glu Gly Cys Glu Lys 
                565                 570                 575     


Ala Phe Ser Arg Leu Glu Asn Leu Lys Ile His Leu Arg Ser His Thr 
            580                 585                 590         


Gly Glu Lys Pro Tyr Leu Cys Gln His Pro Gly Cys Gln Lys Ala Phe 
        595                 600                 605             


Ser Asn Ser Ser Asp Arg Ala Lys His Gln Arg Thr His Leu Asp Thr 
    610                 615                 620                 


Lys Pro Tyr Ala Cys Gln Ile Pro Gly Cys Thr Lys Arg Tyr Thr Asp 
625                 630                 635                 640 


Pro Ser Ser Leu Arg Lys His Val Lys Ala His Ser Ser Lys Glu Gln 
                645                 650                 655     


Gln Ala Arg Lys Lys Leu Arg Ser Ser Thr Glu Leu His Pro Asp Leu 
            660                 665                 670         


Leu Thr Asp Cys Leu Thr Val Gln Ser Leu Gln Pro Ala Thr Ser Pro 
        675                 680                 685             


Arg Asp Ala Ala Ala Glu Gly Thr Val Gly Arg Ser Pro Gly Pro Gly 
    690                 695                 700                 


Pro Asp Leu Tyr Ser Ala Pro Ile Phe Ser Ser Asn Tyr Ser Ser Arg 
705                 710                 715                 720 


Ser Gly Thr Ala Ala Gly Ala Val Pro Pro Pro His Pro Val Ser His 
                725                 730                 735     


Pro Ser Pro Gly His Asn Val Gln Gly Ser Pro His Asn Pro Ser Ser 
            740                 745                 750         


Gln Leu Pro Pro Leu Thr Ala Val Asp Ala Gly Ala Glu Arg Phe Ala 
        755                 760                 765             


Pro Ser Ala Pro Ser Pro His His Ile Ser Pro Arg Arg Val Pro Ala 
    770                 775                 780                 


Pro Ser Ser Ile Leu Gln Arg Thr Gln Pro Pro Tyr Thr Gln Gln Pro 
785                 790                 795                 800 


Ser Gly Ser His Leu Lys Ser Tyr Gln Pro Glu Thr Asn Ser Ser Phe 
                805                 810                 815     


Gln Pro Asn Gly Ile His Val His Gly Phe Tyr Gly Gln Leu Gln Lys 
            820                 825                 830         


Phe Cys Pro Pro His Tyr Pro Asp Ser Gln Arg Ile Val Pro Pro Val 
        835                 840                 845             


Ser Ser Cys Ser Val Val Pro Ser Phe Glu Asp Cys Leu Val Pro Thr 
    850                 855                 860                 


Ser Met Gly Gln Ala Ser Phe Asp Val Phe His Arg Ala Phe Ser Thr 
865                 870                 875                 880 


His Ser Gly Ile Thr Val Tyr Asp Leu Pro Ser Ser Ser Ser Ser Leu 
                885                 890                 895     


Phe Gly Glu Ser Leu Arg Ser Gly Ala Glu Asp Ala Thr Phe Leu Gln 
            900                 905                 910         


Ile Ser Thr Val Asp Arg Cys Pro Ser Gln Leu Ser Ser Val Tyr Thr 
        915                 920                 925             


Glu Gly 
    930 


<210>  3040
<211>  551
<212>  PRT
<213>  homo sapiens

<400>  3040

Met Ala Asp Gly Val Asp His Ile Asp Ile Tyr Ala Asp Val Gly Glu 
1               5                   10                  15      


Glu Phe Asn Gln Glu Ala Glu Tyr Gly Gly His Asp Gln Ile Asp Leu 
            20                  25                  30          


Tyr Asp Asp Val Ile Ser Pro Ser Ala Asn Asn Gly Asp Ala Pro Glu 
        35                  40                  45              


Asp Arg Asp Tyr Met Asp Thr Leu Pro Pro Thr Val Gly Asp Asp Val 
    50                  55                  60                  


Gly Lys Gly Ala Ala Pro Asn Val Val Tyr Thr Tyr Thr Gly Lys Arg 
65                  70                  75                  80  


Ile Ala Leu Tyr Ile Gly Asn Leu Thr Trp Trp Thr Thr Asp Glu Asp 
                85                  90                  95      


Leu Thr Glu Ala Val His Ser Leu Gly Val Asn Asp Ile Leu Glu Ile 
            100                 105                 110         


Lys Phe Phe Glu Asn Arg Ala Asn Gly Gln Ser Lys Gly Phe Ala Leu 
        115                 120                 125             


Val Gly Val Gly Ser Glu Ala Ser Ser Lys Lys Leu Met Asp Leu Leu 
    130                 135                 140                 


Pro Lys Arg Glu Leu His Gly Gln Asn Pro Val Val Thr Pro Cys Asn 
145                 150                 155                 160 


Lys Gln Phe Leu Ser Gln Phe Glu Met Gln Ser Arg Lys Thr Thr Gln 
                165                 170                 175     


Ser Gly Gln Met Ser Gly Glu Gly Lys Ala Gly Pro Pro Gly Gly Ser 
            180                 185                 190         


Ser Arg Ala Ala Phe Pro Gln Gly Gly Arg Gly Arg Gly Arg Phe Pro 
        195                 200                 205             


Gly Ala Val Pro Gly Gly Asp Arg Phe Pro Gly Pro Ala Gly Pro Gly 
    210                 215                 220                 


Gly Pro Pro Pro Pro Phe Pro Ala Gly Gln Thr Pro Pro Arg Pro Pro 
225                 230                 235                 240 


Leu Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly Pro Pro Pro Pro Gly 
                245                 250                 255     


Gln Val Leu Pro Pro Pro Leu Ala Gly Pro Pro Asn Arg Gly Asp Arg 
            260                 265                 270         


Pro Pro Pro Pro Val Leu Phe Pro Gly Gln Pro Phe Gly Gln Pro Pro 
        275                 280                 285             


Leu Gly Pro Leu Pro Pro Gly Pro Pro Pro Pro Val Pro Gly Tyr Gly 
    290                 295                 300                 


Pro Pro Pro Gly Pro Pro Pro Pro Gln Gln Gly Pro Pro Pro Pro Pro 
305                 310                 315                 320 


Gly Pro Phe Pro Pro Arg Pro Pro Gly Pro Leu Gly Pro Pro Leu Thr 
                325                 330                 335     


Leu Ala Pro Pro Pro His Leu Pro Gly Pro Pro Pro Gly Ala Pro Pro 
            340                 345                 350         


Pro Ala Pro His Val Asn Pro Ala Phe Phe Pro Pro Pro Thr Asn Ser 
        355                 360                 365             


Gly Met Pro Thr Ser Asp Ser Arg Gly Pro Pro Pro Thr Asp Pro Tyr 
    370                 375                 380                 


Gly Arg Pro Pro Pro Tyr Asp Arg Gly Asp Tyr Gly Pro Pro Gly Arg 
385                 390                 395                 400 


Glu Met Asp Thr Ala Arg Thr Pro Leu Ser Glu Ala Glu Phe Glu Glu 
                405                 410                 415     


Ile Met Asn Arg Asn Arg Ala Ile Ser Ser Ser Ala Ile Ser Arg Ala 
            420                 425                 430         


Val Ser Asp Ala Ser Ala Gly Asp Tyr Gly Ser Ala Ile Glu Thr Leu 
        435                 440                 445             


Val Thr Ala Ile Ser Leu Ile Lys Gln Ser Lys Val Ser Ala Asp Asp 
    450                 455                 460                 


Arg Cys Lys Val Leu Ile Ser Ser Leu Gln Asp Cys Leu His Gly Ile 
465                 470                 475                 480 


Glu Ser Lys Ser Tyr Gly Ser Gly Ser Arg Arg Glu Arg Ser Arg Glu 
                485                 490                 495     


Arg Asp His Ser Arg Ser Arg Glu Lys Ser Arg Arg His Lys Ser Arg 
            500                 505                 510         


Ser Arg Asp Arg His Asp Asp Tyr Tyr Arg Glu Arg Ser Arg Glu Arg 
        515                 520                 525             


Glu Arg His Arg Asp Arg Asp Arg Asp Arg Asp Arg Glu Arg Asp Arg 
    530                 535                 540                 


Glu Arg Glu Tyr Arg His Arg 
545                 550     


<210>  3041
<211>  200
<212>  PRT
<213>  homo sapiens

<400>  3041

Met Ala Ser Ser Leu Thr Cys Thr Gly Val Ile Trp Ala Leu Leu Ser 
1               5                   10                  15      


Phe Leu Cys Ala Ala Thr Ser Cys Val Gly Phe Phe Met Pro Tyr Trp 
            20                  25                  30          


Leu Trp Gly Ser Gln Leu Gly Lys Pro Val Ser Phe Gly Thr Phe Arg 
        35                  40                  45              


Arg Cys Ser Tyr Pro Val His Asp Glu Ser Arg Gln Met Met Val Met 
    50                  55                  60                  


Val Glu Glu Cys Gly Arg Tyr Ala Ser Phe Gln Gly Ile Pro Ser Ala 
65                  70                  75                  80  


Glu Trp Arg Ile Cys Thr Ile Val Thr Gly Leu Gly Cys Gly Leu Leu 
                85                  90                  95      


Leu Leu Val Ala Leu Thr Ala Leu Met Gly Cys Cys Val Ser Asp Leu 
            100                 105                 110         


Ile Ser Arg Thr Val Gly Arg Val Ala Gly Gly Ile Gln Phe Leu Gly 
        115                 120                 125             


Gly Leu Leu Ile Gly Ala Gly Cys Ala Leu Tyr Pro Leu Gly Trp Asp 
    130                 135                 140                 


Ser Glu Glu Val Arg Gln Thr Cys Gly Tyr Thr Ser Gly Gln Phe Asp 
145                 150                 155                 160 


Leu Gly Lys Cys Glu Ile Gly Trp Ala Tyr Tyr Cys Thr Gly Ala Gly 
                165                 170                 175     


Ala Thr Ala Ala Met Leu Leu Cys Thr Trp Leu Ala Cys Phe Ser Gly 
            180                 185                 190         


Lys Lys Gln Lys His Tyr Pro Tyr 
        195                 200 


<210>  3042
<211>  2073
<212>  PRT
<213>  homo sapiens

<400>  3042

Met Ala Glu Val Arg Lys Phe Thr Lys Arg Leu Ser Lys Pro Gly Thr 
1               5                   10                  15      


Ala Ala Glu Leu Arg Gln Ser Val Ser Glu Ala Val Arg Gly Ser Val 
            20                  25                  30          


Val Leu Glu Lys Ala Lys Val Val Glu Pro Leu Asp Tyr Glu Asn Val 
        35                  40                  45              


Ile Ala Gln Arg Lys Thr Gln Ile Tyr Ser Asp Pro Leu Arg Asp Leu 
    50                  55                  60                  


Leu Met Phe Pro Met Glu Asp Ile Ser Ile Ser Val Ile Gly Arg Gln 
65                  70                  75                  80  


Arg Arg Thr Val Gln Ser Thr Val Pro Glu Asp Ala Glu Lys Arg Ala 
                85                  90                  95      


Gln Ser Leu Phe Val Lys Glu Cys Ile Lys Thr Tyr Ser Thr Asp Trp 
            100                 105                 110         


His Val Val Asn Tyr Lys Tyr Glu Asp Phe Ser Gly Asp Phe Arg Met 
        115                 120                 125             


Leu Pro Cys Lys Ser Leu Arg Pro Glu Lys Ile Pro Asn His Val Phe 
    130                 135                 140                 


Glu Ile Asp Glu Asp Cys Glu Lys Asp Glu Asp Ser Ser Ser Leu Cys 
145                 150                 155                 160 


Ser Gln Lys Gly Gly Val Ile Lys Gln Gly Trp Leu His Lys Ala Asn 
                165                 170                 175     


Val Asn Ser Thr Ile Thr Val Thr Met Lys Val Phe Lys Arg Arg Tyr 
            180                 185                 190         


Phe Tyr Leu Thr Gln Leu Pro Asp Gly Ser Tyr Ile Leu Asn Ser Tyr 
        195                 200                 205             


Lys Asp Glu Lys Asn Ser Lys Glu Ser Lys Gly Cys Ile Tyr Leu Asp 
    210                 215                 220                 


Ala Cys Ile Asp Val Val Gln Cys Pro Lys Met Arg Arg His Ala Phe 
225                 230                 235                 240 


Glu Leu Lys Met Leu Asp Lys Tyr Ser His Tyr Leu Ala Ala Glu Thr 
                245                 250                 255     


Glu Gln Glu Met Glu Glu Trp Leu Ile Thr Leu Lys Lys Ile Ile Gln 
            260                 265                 270         


Ile Asn Thr Asp Ser Leu Val Gln Glu Lys Lys Glu Thr Val Glu Thr 
        275                 280                 285             


Ala Gln Asp Asp Glu Thr Ser Ser Gln Gly Lys Ala Glu Asn Ile Met 
    290                 295                 300                 


Ala Ser Leu Glu Arg Ser Met His Pro Glu Leu Met Lys Tyr Gly Arg 
305                 310                 315                 320 


Glu Thr Glu Gln Leu Asn Lys Leu Ser Arg Gly Asp Gly Arg Gln Asn 
                325                 330                 335     


Leu Phe Ser Phe Asp Ser Glu Val Gln Arg Leu Asp Phe Ser Gly Ile 
            340                 345                 350         


Glu Pro Asp Ile Lys Pro Phe Glu Glu Lys Cys Asn Lys Arg Phe Leu 
        355                 360                 365             


Val Asn Cys His Asp Leu Thr Phe Asn Ile Leu Gly Gln Ile Gly Asp 
    370                 375                 380                 


Asn Ala Lys Gly Pro Pro Thr Asn Val Glu Pro Phe Phe Ile Asn Leu 
385                 390                 395                 400 


Ala Leu Phe Asp Val Lys Asn Asn Cys Lys Ile Ser Ala Asp Phe His 
                405                 410                 415     


Val Asp Leu Asn Pro Pro Ser Val Arg Glu Met Leu Trp Gly Ser Ser 
            420                 425                 430         


Thr Gln Leu Ala Ser Asp Gly Ser Pro Lys Gly Ser Ser Pro Glu Ser 
        435                 440                 445             


Tyr Ile His Gly Ile Ala Glu Ser Gln Leu Arg Tyr Ile Gln Gln Gly 
    450                 455                 460                 


Ile Phe Ser Val Thr Asn Pro His Pro Glu Ile Phe Leu Val Ala Arg 
465                 470                 475                 480 


Ile Glu Lys Val Leu Gln Gly Asn Ile Thr His Cys Ala Glu Pro Tyr 
                485                 490                 495     


Ile Lys Asn Ser Asp Pro Val Lys Thr Ala Gln Lys Val His Arg Thr 
            500                 505                 510         


Ala Lys Gln Val Cys Ser Arg Leu Gly Gln Tyr Arg Met Pro Phe Ala 
        515                 520                 525             


Trp Ala Ala Arg Pro Ile Phe Lys Asp Thr Gln Gly Ser Leu Asp Leu 
    530                 535                 540                 


Asp Gly Arg Phe Ser Pro Leu Tyr Lys Gln Asp Ser Ser Lys Leu Ser 
545                 550                 555                 560 


Ser Glu Asp Ile Leu Lys Leu Leu Ser Glu Tyr Lys Lys Pro Glu Lys 
                565                 570                 575     


Thr Lys Leu Gln Ile Ile Pro Gly Gln Leu Asn Ile Thr Val Glu Cys 
            580                 585                 590         


Val Pro Val Asp Leu Ser Asn Cys Ile Thr Ser Ser Tyr Val Pro Leu 
        595                 600                 605             


Lys Pro Phe Glu Lys Asn Cys Gln Asn Ile Thr Val Glu Val Glu Glu 
    610                 615                 620                 


Phe Val Pro Glu Met Thr Lys Tyr Cys Tyr Pro Phe Thr Ile Tyr Lys 
625                 630                 635                 640 


Asn His Leu Tyr Val Tyr Pro Leu Gln Leu Lys Tyr Asp Ser Gln Lys 
                645                 650                 655     


Thr Phe Ala Lys Ala Arg Asn Ile Ala Val Cys Val Glu Phe Arg Asp 
            660                 665                 670         


Ser Asp Glu Ser Asp Ala Ser Ala Leu Lys Cys Ile Tyr Gly Lys Pro 
        675                 680                 685             


Ala Gly Ser Val Phe Thr Thr Asn Ala Tyr Ala Val Val Ser His His 
    690                 695                 700                 


Asn Gln Asn Pro Glu Phe Tyr Asp Glu Ile Lys Ile Glu Leu Pro Ile 
705                 710                 715                 720 


His Leu His Gln Lys His His Leu Leu Phe Thr Phe Tyr His Val Ser 
                725                 730                 735     


Cys Glu Ile Asn Thr Lys Gly Thr Thr Lys Lys Gln Asp Thr Val Glu 
            740                 745                 750         


Thr Pro Val Gly Phe Ala Trp Val Pro Leu Leu Lys Asp Gly Arg Ile 
        755                 760                 765             


Ile Thr Phe Glu Gln Gln Leu Pro Val Ser Ala Asn Leu Pro Pro Gly 
    770                 775                 780                 


Tyr Leu Asn Leu Asn Asp Ala Glu Ser Arg Arg Gln Cys Asn Val Asp 
785                 790                 795                 800 


Ile Lys Trp Val Asp Gly Ala Lys Pro Leu Leu Lys Ile Lys Ser His 
                805                 810                 815     


Leu Glu Ser Thr Ile Tyr Thr Gln Asp Leu His Val His Lys Phe Phe 
            820                 825                 830         


His His Cys Gln Leu Ile Gln Ser Gly Ser Lys Glu Val Pro Gly Glu 
        835                 840                 845             


Leu Ile Lys Tyr Leu Lys Cys Leu His Ala Met Glu Ile Gln Val Met 
    850                 855                 860                 


Ile Gln Phe Leu Pro Val Ile Leu Met Gln Leu Phe Arg Val Leu Thr 
865                 870                 875                 880 


Asn Met Thr His Glu Asp Asp Val Pro Ile Asn Cys Thr Met Val Leu 
                885                 890                 895     


Leu His Ile Val Ser Lys Cys His Glu Glu Gly Leu Asp Ser Tyr Leu 
            900                 905                 910         


Arg Ser Phe Ile Lys Tyr Ser Phe Arg Pro Glu Lys Pro Ser Ala Pro 
        915                 920                 925             


Gln Ala Gln Leu Ile His Glu Thr Leu Ala Thr Thr Met Ile Ala Ile 
    930                 935                 940                 


Leu Lys Gln Ser Ala Asp Phe Leu Ser Ile Asn Lys Leu Leu Lys Tyr 
945                 950                 955                 960 


Ser Trp Phe Phe Phe Glu Ile Ile Ala Lys Ser Met Ala Thr Tyr Leu 
                965                 970                 975     


Leu Glu Glu Asn Lys Ile Lys Leu Pro Arg Gly Gln Arg Phe Pro Glu 
            980                 985                 990         


Thr Tyr His His Val Leu His Ser  Leu Leu Leu Ala Ile  Ile Pro His 
        995                 1000                 1005             


Val Thr  Ile Arg Tyr Ala Glu  Ile Pro Asp Glu Ser  Arg Asn Val 
    1010                 1015                 1020             


Asn Tyr  Ser Leu Ala Ser Phe  Leu Lys Arg Cys Leu  Thr Leu Met 
    1025                 1030                 1035             


Asp Arg  Gly Phe Ile Phe Asn  Leu Ile Asn Asp Tyr  Ile Ser Gly 
    1040                 1045                 1050             


Phe Ser  Pro Lys Asp Pro Lys  Val Leu Ala Glu Tyr  Lys Phe Glu 
    1055                 1060                 1065             


Phe Leu  Gln Thr Ile Cys Asn  His Glu His Tyr Ile  Pro Leu Asn 
    1070                 1075                 1080             


Leu Pro  Met Ala Phe Ala Lys  Pro Lys Leu Gln Arg  Val Gln Asp 
    1085                 1090                 1095             


Ser Asn  Leu Glu Tyr Ser Leu  Ser Asp Glu Tyr Cys  Lys His His 
    1100                 1105                 1110             


Phe Leu  Val Gly Leu Leu Leu  Arg Glu Thr Ser Ile  Ala Leu Gln 
    1115                 1120                 1125             


Asp Asn  Tyr Glu Ile Arg Tyr  Thr Ala Ile Ser Val  Ile Lys Asn 
    1130                 1135                 1140             


Leu Leu  Ile Lys His Ala Phe  Asp Thr Arg Tyr Gln  His Lys Asn 
    1145                 1150                 1155             


Gln Gln  Ala Lys Ile Ala Gln  Leu Tyr Leu Pro Phe  Val Gly Leu 
    1160                 1165                 1170             


Leu Leu  Glu Asn Ile Gln Arg  Leu Ala Gly Arg Asp  Thr Leu Tyr 
    1175                 1180                 1185             


Ser Cys  Ala Ala Met Pro Asn  Ser Ala Ser Arg Asp  Glu Phe Pro 
    1190                 1195                 1200             


Cys Gly  Phe Thr Ser Pro Ala  Asn Arg Gly Ser Leu  Ser Thr Asp 
    1205                 1210                 1215             


Lys Asp  Thr Ala Tyr Gly Ser  Phe Gln Asn Gly His  Gly Ile Lys 
    1220                 1225                 1230             


Arg Glu  Asp Ser Arg Gly Ser  Leu Ile Pro Glu Gly  Ala Thr Gly 
    1235                 1240                 1245             


Phe Pro  Asp Gln Gly Asn Thr  Gly Glu Asn Thr Arg  Gln Ser Ser 
    1250                 1255                 1260             


Thr Arg  Ser Ser Val Ser Gln  Tyr Asn Arg Leu Asp  Gln Tyr Glu 
    1265                 1270                 1275             


Ile Arg  Ser Leu Leu Met Cys  Tyr Leu Tyr Ile Val  Lys Met Ile 
    1280                 1285                 1290             


Ser Glu  Asp Thr Leu Leu Thr  Tyr Trp Asn Lys Val  Ser Pro Gln 
    1295                 1300                 1305             


Glu Leu  Ile Asn Ile Leu Ile  Leu Leu Glu Val Cys  Leu Phe His 
    1310                 1315                 1320             


Phe Arg  Tyr Met Gly Lys Arg  Asn Ile Ala Arg Val  His Asp Ala 
    1325                 1330                 1335             


Trp Leu  Ser Lys His Phe Gly  Ile Asp Arg Lys Ser  Gln Thr Met 
    1340                 1345                 1350             


Pro Ala  Leu Arg Asn Arg Ser  Gly Val Met Gln Ala  Arg Leu Gln 
    1355                 1360                 1365             


His Leu  Ser Ser Leu Glu Ser  Ser Phe Thr Leu Asn  His Ser Ser 
    1370                 1375                 1380             


Thr Thr  Thr Glu Ala Asp Ile  Phe His Gln Ala Leu  Leu Glu Gly 
    1385                 1390                 1395             


Asn Thr  Ala Thr Glu Val Ser  Leu Thr Val Leu Asp  Thr Ile Ser 
    1400                 1405                 1410             


Phe Phe  Thr Gln Cys Phe Lys  Thr Gln Leu Leu Asn  Asn Asp Gly 
    1415                 1420                 1425             


His Asn  Pro Leu Met Lys Lys  Val Phe Asp Ile His  Leu Ala Phe 
    1430                 1435                 1440             


Leu Lys  Asn Gly Gln Ser Glu  Val Ser Leu Lys His  Val Phe Ala 
    1445                 1450                 1455             


Ser Leu  Arg Ala Phe Ile Ser  Lys Phe Pro Ser Ala  Phe Phe Lys 
    1460                 1465                 1470             


Gly Arg  Val Asn Met Cys Ala  Ala Phe Cys Tyr Glu  Val Leu Lys 
    1475                 1480                 1485             


Cys Cys  Thr Ser Lys Ile Ser  Ser Thr Arg Asn Glu  Ala Ser Ala 
    1490                 1495                 1500             


Leu Leu  Tyr Leu Leu Met Arg  Asn Asn Phe Glu Tyr  Thr Lys Arg 
    1505                 1510                 1515             


Lys Thr  Phe Leu Arg Thr His  Leu Gln Ile Ile Ile  Ala Val Ser 
    1520                 1525                 1530             


Gln Leu  Ile Ala Asp Val Ala  Leu Ser Gly Gly Ser  Arg Phe Gln 
    1535                 1540                 1545             


Glu Ser  Leu Phe Ile Ile Asn  Asn Phe Ala Asn Ser  Asp Arg Pro 
    1550                 1555                 1560             


Met Lys  Ala Thr Ala Phe Pro  Ala Glu Val Lys Asp  Leu Thr Lys 
    1565                 1570                 1575             


Arg Ile  Arg Thr Val Leu Met  Ala Thr Ala Gln Met  Lys Glu His 
    1580                 1585                 1590             


Glu Lys  Asp Pro Glu Met Leu  Ile Asp Leu Gln Tyr  Ser Leu Ala 
    1595                 1600                 1605             


Lys Ser  Tyr Ala Ser Thr Pro  Glu Leu Arg Lys Thr  Trp Leu Asp 
    1610                 1615                 1620             


Ser Met  Ala Lys Ile His Val  Lys Asn Gly Asp Phe  Ser Glu Ala 
    1625                 1630                 1635             


Ala Met  Cys Tyr Val His Val  Ala Ala Leu Val Ala  Glu Phe Leu 
    1640                 1645                 1650             


His Arg  Lys Lys Leu Phe Pro  Asn Gly Cys Ser Ala  Phe Lys Lys 
    1655                 1660                 1665             


Ile Thr  Pro Asn Ile Asp Glu  Glu Gly Ala Met Lys  Glu Asp Ala 
    1670                 1675                 1680             


Gly Met  Met Asp Val His Tyr  Ser Glu Glu Val Leu  Leu Glu Leu 
    1685                 1690                 1695             


Leu Glu  Gln Cys Val Asp Gly  Leu Trp Lys Ala Glu  Arg Tyr Glu 
    1700                 1705                 1710             


Ile Ile  Ser Glu Ile Ser Lys  Leu Ile Val Pro Ile  Tyr Glu Lys 
    1715                 1720                 1725             


Arg Arg  Glu Phe Glu Lys Leu  Thr Gln Val Tyr Arg  Thr Leu His 
    1730                 1735                 1740             


Gly Ala  Tyr Thr Lys Ile Leu  Glu Val Met His Thr  Lys Lys Arg 
    1745                 1750                 1755             


Leu Leu  Gly Thr Phe Phe Arg  Val Ala Phe Tyr Gly  Gln Ser Phe 
    1760                 1765                 1770             


Phe Glu  Glu Glu Asp Gly Lys  Glu Tyr Ile Tyr Lys  Glu Pro Lys 
    1775                 1780                 1785             


Leu Thr  Gly Leu Ser Glu Ile  Ser Leu Arg Leu Val  Lys Leu Tyr 
    1790                 1795                 1800             


Gly Glu  Lys Phe Gly Thr Glu  Asn Val Lys Ile Ile  Gln Asp Ser 
    1805                 1810                 1815             


Asp Lys  Val Asn Ala Lys Glu  Leu Asp Pro Lys Tyr  Ala His Ile 
    1820                 1825                 1830             


Gln Val  Thr Tyr Val Lys Pro  Tyr Phe Asp Asp Lys  Glu Leu Thr 
    1835                 1840                 1845             


Glu Arg  Lys Thr Glu Phe Glu  Arg Asn His Asn Ile  Ser Arg Phe 
    1850                 1855                 1860             


Val Phe  Glu Ala Pro Tyr Thr  Leu Ser Gly Lys Lys  Gln Gly Cys 
    1865                 1870                 1875             


Ile Glu  Glu Gln Cys Lys Arg  Arg Thr Ile Leu Thr  Thr Ser Asn 
    1880                 1885                 1890             


Ser Phe  Pro Tyr Val Lys Lys  Arg Ile Pro Ile Asn  Cys Glu Gln 
    1895                 1900                 1905             


Gln Ile  Asn Leu Lys Pro Ile  Asp Val Ala Thr Asp  Glu Ile Lys 
    1910                 1915                 1920             


Asp Lys  Thr Ala Glu Leu Gln  Lys Leu Cys Ser Ser  Thr Asp Val 
    1925                 1930                 1935             


Asp Met  Ile Gln Leu Gln Leu  Lys Leu Gln Gly Cys  Val Ser Val 
    1940                 1945                 1950             


Gln Val  Asn Ala Gly Pro Leu  Ala Tyr Ala Arg Ala  Phe Leu Asn 
    1955                 1960                 1965             


Asp Ser  Gln Ala Ser Lys Tyr  Pro Pro Lys Lys Val  Ser Glu Leu 
    1970                 1975                 1980             


Lys Asp  Met Phe Arg Lys Phe  Ile Gln Ala Cys Ser  Ile Ala Leu 
    1985                 1990                 1995             


Glu Leu  Asn Glu Arg Leu Ile  Lys Glu Asp Gln Val  Glu Tyr His 
    2000                 2005                 2010             


Glu Gly  Leu Lys Ser Asn Phe  Arg Asp Met Val Lys  Glu Leu Ser 
    2015                 2020                 2025             


Asp Ile  Ile His Glu Gln Ile  Leu Gln Glu Asp Thr  Met His Ser 
    2030                 2035                 2040             


Pro Trp  Met Ser Asn Thr Leu  His Val Phe Cys Ala  Ile Ser Gly 
    2045                 2050                 2055             


Thr Ser  Ser Asp Arg Gly Tyr  Gly Ser Pro Arg Tyr  Ala Glu Val 
    2060                 2065                 2070             


<210>  3043
<211>  1944
<212>  PRT
<213>  homo sapiens

<400>  3043

Met Ser Asn Phe Tyr Glu Glu Arg Thr Thr Met Ile Ala Ala Arg Asp 
1               5                   10                  15      


Leu Gln Glu Phe Val Pro Phe Gly Arg Asp His Cys Lys His His Pro 
            20                  25                  30          


Asn Ala Leu Asn Leu Gln Leu Arg Gln Leu Gln Pro Ala Ser Glu Leu 
        35                  40                  45              


Trp Ser Ser Asp Gly Ala Ala Gly Leu Val Gly Ser Leu Gln Glu Val 
    50                  55                  60                  


Thr Ile His Glu Lys Gln Lys Glu Ser Trp Gln Leu Arg Lys Gly Val 
65                  70                  75                  80  


Ser Glu Ile Gly Glu Asp Val Asp Tyr Asp Glu Glu Leu Tyr Val Ala 
                85                  90                  95      


Gly Asn Met Val Ile Trp Ser Lys Gly Ser Lys Ser Gln Ala Leu Ala 
            100                 105                 110         


Val Tyr Lys Ala Phe Thr Val Asp Ser Pro Val Gln Gln Ala Leu Trp 
        115                 120                 125             


Cys Asp Phe Ile Ile Ser Gln Asp Lys Ser Glu Lys Ala Tyr Ser Ser 
    130                 135                 140                 


Asn Glu Val Glu Lys Cys Ile Cys Ile Leu Gln Ser Ser Cys Ile Asn 
145                 150                 155                 160 


Met His Ser Ile Glu Gly Lys Asp Tyr Ile Ala Ser Leu Pro Phe Gln 
                165                 170                 175     


Val Ala Asn Val Trp Pro Thr Lys Tyr Gly Leu Leu Phe Glu Arg Ser 
            180                 185                 190         


Ala Ser Ser His Glu Val Pro Pro Gly Ser Pro Arg Glu Pro Leu Pro 
        195                 200                 205             


Thr Met Phe Ser Met Leu His Pro Leu Asp Glu Ile Thr Pro Leu Val 
    210                 215                 220                 


Cys Lys Ser Gly Ser Leu Phe Gly Ser Ser Arg Val Gln Tyr Val Val 
225                 230                 235                 240 


Asp His Ala Met Lys Ile Val Phe Leu Asn Thr Asp Pro Ser Ile Val 
                245                 250                 255     


Met Thr Tyr Asp Ala Val Gln Asn Val His Ser Val Trp Thr Leu Arg 
            260                 265                 270         


Arg Val Lys Ser Glu Glu Glu Asn Val Val Leu Lys Phe Ser Glu Gln 
        275                 280                 285             


Gly Gly Thr Pro Gln Asn Val Ala Thr Ser Ser Ser Leu Thr Ala His 
    290                 295                 300                 


Leu Arg Ser Leu Ser Lys Gly Asp Ser Pro Val Thr Ser Pro Phe Gln 
305                 310                 315                 320 


Asn Tyr Ser Ser Ile His Ser Gln Ser Arg Ser Thr Ser Ser Pro Ser 
                325                 330                 335     


Leu His Ser Arg Ser Pro Ser Ile Ser Asn Met Ala Ala Leu Ser Arg 
            340                 345                 350         


Ala His Ser Pro Ala Leu Gly Val His Ser Phe Ser Gly Val Gln Arg 
        355                 360                 365             


Phe Asn Ile Ser Ser His Asn Gln Ser Pro Lys Arg His Ser Ile Ser 
    370                 375                 380                 


His Ser Pro Asn Ser Asn Ser Asn Gly Ser Phe Leu Ala Pro Glu Thr 
385                 390                 395                 400 


Glu Pro Ile Val Pro Glu Leu Cys Ile Asp His Leu Trp Thr Glu Thr 
                405                 410                 415     


Ile Thr Asn Ile Arg Glu Lys Asn Ser Gln Ala Ser Lys Val Phe Ile 
            420                 425                 430         


Thr Ser Asp Leu Cys Gly Gln Lys Phe Leu Cys Phe Leu Val Glu Ser 
        435                 440                 445             


Gln Leu Gln Leu Arg Cys Val Lys Phe Gln Glu Ser Asn Asp Lys Thr 
    450                 455                 460                 


Gln Leu Ile Phe Gly Ser Val Thr Asn Ile Pro Ala Lys Asp Ala Ala 
465                 470                 475                 480 


Pro Val Glu Lys Ile Asp Thr Met Leu Val Leu Glu Gly Ser Gly Asn 
                485                 490                 495     


Leu Val Leu Tyr Thr Gly Val Val Arg Val Gly Lys Val Phe Ile Pro 
            500                 505                 510         


Gly Leu Pro Ala Pro Ser Leu Thr Met Ser Asn Thr Met Pro Arg Pro 
        515                 520                 525             


Ser Thr Pro Leu Asp Gly Val Ser Thr Pro Lys Pro Leu Ser Lys Leu 
    530                 535                 540                 


Leu Gly Ser Leu Asp Glu Val Val Leu Leu Ser Pro Val Pro Glu Leu 
545                 550                 555                 560 


Arg Asp Ser Ser Lys Leu His Asp Ser Leu Tyr Asn Glu Asp Cys Thr 
                565                 570                 575     


Phe Gln Gln Leu Gly Thr Tyr Ile His Ser Ile Arg Asp Pro Val His 
            580                 585                 590         


Asn Arg Val Thr Leu Glu Leu Ser Asn Gly Ser Met Val Arg Ile Thr 
        595                 600                 605             


Ile Pro Glu Ile Ala Thr Ser Glu Leu Val Gln Thr Cys Leu Gln Ala 
    610                 615                 620                 


Ile Lys Phe Ile Leu Pro Lys Glu Ile Ala Val Gln Met Leu Val Lys 
625                 630                 635                 640 


Trp Tyr Asn Val His Ser Ala Pro Gly Gly Pro Ser Tyr His Ser Glu 
                645                 650                 655     


Trp Asn Leu Phe Val Thr Cys Leu Met Asn Met Met Gly Tyr Asn Thr 
            660                 665                 670         


Asp Arg Leu Ala Trp Thr Arg Asn Phe Asp Phe Glu Gly Ser Leu Ser 
        675                 680                 685             


Pro Val Ile Ala Pro Lys Lys Ala Arg Pro Ser Glu Thr Gly Ser Asp 
    690                 695                 700                 


Asp Asp Trp Glu Tyr Leu Leu Asn Ser Asp Tyr His Gln Asn Val Glu 
705                 710                 715                 720 


Ser His Leu Leu Asn Arg Ser Leu Cys Leu Ser Pro Ser Glu Ala Ser 
                725                 730                 735     


Gln Met Lys Asp Glu Asp Phe Ser Gln Asn Leu Ser Leu Asp Ser Ser 
            740                 745                 750         


Thr Leu Leu Phe Thr His Ile Pro Ala Ile Phe Phe Val Leu His Leu 
        755                 760                 765             


Val Tyr Glu Glu Leu Lys Leu Asn Thr Leu Met Gly Glu Gly Ile Cys 
    770                 775                 780                 


Ser Leu Val Glu Leu Leu Val Gln Leu Ala Arg Asp Leu Lys Leu Gly 
785                 790                 795                 800 


Pro Tyr Val Asp His Tyr Tyr Arg Asp Tyr Pro Thr Leu Val Arg Thr 
                805                 810                 815     


Thr Gly Gln Val Cys Thr Ile Asp Pro Gly Gln Thr Gly Phe Met His 
            820                 825                 830         


His Pro Ser Phe Phe Thr Ser Glu Pro Pro Ser Ile Tyr Gln Trp Val 
        835                 840                 845             


Ser Ser Cys Leu Lys Gly Glu Gly Met Pro Pro Tyr Pro Tyr Leu Pro 
    850                 855                 860                 


Gly Ile Cys Glu Arg Ser Arg Leu Val Val Leu Ser Ile Ala Leu Tyr 
865                 870                 875                 880 


Ile Leu Gly Asp Glu Ser Leu Val Ser Asp Glu Ser Ser Gln Tyr Leu 
                885                 890                 895     


Thr Arg Ile Thr Ile Ala Pro Gln Lys Leu Gln Val Glu Gln Glu Glu 
            900                 905                 910         


Asn Arg Phe Ser Phe Arg His Ser Thr Ser Val Ser Ser Leu Ala Glu 
        915                 920                 925             


Arg Leu Val Val Trp Met Thr Asn Val Gly Phe Thr Leu Arg Asp Leu 
    930                 935                 940                 


Glu Thr Leu Pro Phe Gly Ile Ala Leu Pro Ile Arg Asp Ala Ile Tyr 
945                 950                 955                 960 


His Cys Arg Glu Gln Pro Ala Ser Asp Trp Pro Glu Ala Val Cys Leu 
                965                 970                 975     


Leu Ile Gly Arg Gln Asp Leu Ser Lys Gln Ala Cys Glu Gly Asn Leu 
            980                 985                 990         


Pro Lys Gly Lys Ser Val Leu Ser  Ser Asp Val Pro Ser  Gly Thr Glu 
        995                 1000                 1005             


Thr Glu  Glu Glu Asp Asp Gly  Met Asn Asp Met Asn  His Glu Val 
    1010                 1015                 1020             


Met Ser  Leu Ile Trp Ser Glu  Asp Leu Arg Val Gln  Asp Val Arg 
    1025                 1030                 1035             


Arg Leu  Leu Gln Ser Ala His  Pro Val Arg Val Asn  Val Val Gln 
    1040                 1045                 1050             


Tyr Pro  Glu Leu Ser Asp His  Glu Phe Ile Glu Glu  Lys Glu Asn 
    1055                 1060                 1065             


Arg Leu  Leu Gln Leu Cys Gln  Arg Thr Met Ala Leu  Pro Val Gly 
    1070                 1075                 1080             


Arg Gly  Met Phe Thr Leu Phe  Ser Tyr His Pro Val  Pro Thr Glu 
    1085                 1090                 1095             


Pro Leu  Pro Ile Pro Lys Leu  Asn Leu Thr Gly Arg  Ala Pro Pro 
    1100                 1105                 1110             


Arg Asn  Thr Thr Val Asp Leu  Asn Ser Gly Asn Ile  Asp Val Pro 
    1115                 1120                 1125             


Pro Asn  Met Thr Ser Trp Ala  Ser Phe His Asn Gly  Val Ala Ala 
    1130                 1135                 1140             


Gly Leu  Lys Ile Ala Pro Ala  Ser Gln Ile Asp Ser  Ala Trp Ile 
    1145                 1150                 1155             


Val Tyr  Asn Lys Pro Lys His  Ala Glu Leu Ala Asn  Glu Tyr Ala 
    1160                 1165                 1170             


Gly Phe  Leu Met Ala Leu Gly  Leu Asn Gly His Leu  Thr Lys Leu 
    1175                 1180                 1185             


Ala Thr  Leu Asn Ile His Asp  Tyr Leu Thr Lys Gly  His Glu Met 
    1190                 1195                 1200             


Thr Ser  Ile Gly Leu Leu Leu  Gly Val Ser Ala Ala  Lys Leu Gly 
    1205                 1210                 1215             


Thr Met  Asp Met Ser Ile Thr  Arg Leu Leu Ser Ile  His Ile Pro 
    1220                 1225                 1230             


Ala Leu  Leu Pro Pro Thr Ser  Thr Glu Leu Asp Val  Pro His Asn 
    1235                 1240                 1245             


Val Gln  Val Ala Ala Val Val  Gly Ile Gly Leu Val  Tyr Gln Gly 
    1250                 1255                 1260             


Thr Ala  His Arg His Thr Ala  Glu Val Leu Leu Ala  Glu Ile Gly 
    1265                 1270                 1275             


Arg Pro  Pro Gly Pro Glu Met  Glu Tyr Cys Thr Asp  Arg Glu Ser 
    1280                 1285                 1290             


Tyr Ser  Leu Ala Ala Gly Leu  Ala Leu Gly Met Val  Cys Leu Gly 
    1295                 1300                 1305             


His Gly  Ser Asn Leu Ile Gly  Met Ser Asp Leu Asn  Val Pro Glu 
    1310                 1315                 1320             


Gln Leu  Tyr Gln Tyr Met Val  Gly Gly His Arg Arg  Phe Gln Thr 
    1325                 1330                 1335             


Gly Met  His Arg Glu Lys His  Lys Ser Pro Ser Tyr  Gln Ile Lys 
    1340                 1345                 1350             


Glu Gly  Asp Thr Ile Asn Val  Asp Val Thr Cys Pro  Gly Ala Thr 
    1355                 1360                 1365             


Leu Ala  Leu Ala Met Ile Tyr  Leu Lys Thr Asn Asn  Arg Ser Ile 
    1370                 1375                 1380             


Ala Asp  Trp Leu Arg Ala Pro  Asp Thr Met Tyr Leu  Leu Asp Phe 
    1385                 1390                 1395             


Val Lys  Pro Glu Phe Leu Leu  Leu Arg Thr Leu Ala  Arg Cys Leu 
    1400                 1405                 1410             


Ile Leu  Trp Asp Asp Ile Leu  Pro Asn Ser Lys Trp  Val Asp Ser 
    1415                 1420                 1425             


Asn Val  Pro Gln Ile Ile Arg  Glu Asn Ser Ile Ser  Leu Ser Glu 
    1430                 1435                 1440             


Ile Glu  Leu Pro Cys Ser Glu  Asp Leu Asn Leu Glu  Thr Leu Ser 
    1445                 1450                 1455             


Gln Ala  His Val Tyr Ile Ile  Ala Gly Ala Cys Leu  Ser Leu Gly 
    1460                 1465                 1470             


Phe Arg  Phe Ala Gly Ser Glu  Asn Leu Ser Ala Phe  Asn Cys Leu 
    1475                 1480                 1485             


His Lys  Phe Ala Lys Asp Phe  Met Thr Tyr Leu Ser  Ala Pro Asn 
    1490                 1495                 1500             


Ala Ser  Val Thr Gly Pro His  Asn Leu Glu Thr Cys  Leu Ser Val 
    1505                 1510                 1515             


Val Leu  Leu Ser Leu Ala Met  Val Met Ala Gly Ser  Gly Asn Leu 
    1520                 1525                 1530             


Lys Val  Leu Gln Leu Cys Arg  Phe Leu His Met Lys  Thr Gly Gly 
    1535                 1540                 1545             


Glu Met  Asn Tyr Gly Phe His  Leu Ala His His Met  Ala Leu Gly 
    1550                 1555                 1560             


Leu Leu  Phe Leu Gly Gly Gly  Arg Tyr Ser Leu Ser  Thr Ser Asn 
    1565                 1570                 1575             


Ser Ser  Ile Ala Ala Leu Leu  Cys Ala Leu Tyr Pro  His Phe Pro 
    1580                 1585                 1590             


Ala His  Ser Thr Asp Asn Arg  Tyr His Leu Gln Ala  Leu Arg His 
    1595                 1600                 1605             


Leu Tyr  Val Leu Ala Ala Glu  Pro Arg Leu Leu Val  Pro Val Asp 
    1610                 1615                 1620             


Val Asp  Thr Asn Thr Pro Cys  Tyr Ala Leu Leu Glu  Val Thr Tyr 
    1625                 1630                 1635             


Lys Gly  Thr Gln Trp Tyr Glu  Gln Thr Lys Glu Glu  Leu Met Ala 
    1640                 1645                 1650             


Pro Thr  Leu Leu Pro Glu Leu  His Leu Leu Lys Gln  Ile Lys Val 
    1655                 1660                 1665             


Lys Gly  Pro Arg Tyr Trp Glu  Leu Leu Ile Asp Leu  Ser Lys Gly 
    1670                 1675                 1680             


Thr Gln  His Leu Lys Ser Ile  Leu Ser Lys Asp Gly  Val Leu Tyr 
    1685                 1690                 1695             


Val Lys  Leu Arg Ala Gly Gln  Leu Ser Tyr Lys Glu  Asp Pro Met 
    1700                 1705                 1710             


Gly Trp  Gln Ser Leu Leu Ala  Gln Thr Val Ala Asn  Arg Asn Ser 
    1715                 1720                 1725             


Glu Ala  Arg Ala Phe Lys Pro  Glu Thr Ile Ser Ala  Phe Thr Ser 
    1730                 1735                 1740             


Asp Pro  Ala Leu Leu Ser Phe  Ala Glu Tyr Phe Cys  Lys Pro Thr 
    1745                 1750                 1755             


Val Asn  Met Gly Gln Lys Gln  Glu Ile Leu Asp Leu  Phe Ser Ser 
    1760                 1765                 1770             


Val Leu  Tyr Glu Cys Val Thr  Gln Glu Thr Pro Glu  Met Leu Pro 
    1775                 1780                 1785             


Ala Tyr  Ile Ala Met Asp Gln  Ala Ile Arg Arg Leu  Gly Arg Arg 
    1790                 1795                 1800             


Glu Met  Ser Glu Thr Ser Glu  Leu Trp Gln Ile Lys  Leu Val Leu 
    1805                 1810                 1815             


Glu Phe  Phe Ser Ser Arg Ser  His Gln Glu Arg Leu  Gln Asn His 
    1820                 1825                 1830             


Pro Lys  Arg Gly Leu Phe Met  Asn Ser Glu Phe Leu  Pro Val Val 
    1835                 1840                 1845             


Lys Cys  Thr Ile Asp Asn Thr  Leu Asp Gln Trp Leu  Gln Val Gly 
    1850                 1855                 1860             


Gly Asp  Met Cys Val His Ala  Tyr Leu Ser Gly Gln  Pro Leu Glu 
    1865                 1870                 1875             


Glu Ser  Gln Leu Ser Met Leu  Ala Cys Phe Leu Val  Tyr His Ser 
    1880                 1885                 1890             


Val Pro  Ala Pro Gln His Leu  Pro Pro Ile Gly Leu  Glu Gly Ser 
    1895                 1900                 1905             


Thr Ser  Phe Ala Glu Leu Leu  Phe Lys Phe Lys Gln  Leu Lys Met 
    1910                 1915                 1920             


Pro Val  Arg Ala Leu Leu Arg  Leu Ala Pro Leu Leu  Leu Gly Asn 
    1925                 1930                 1935             


Pro Gln  Pro Met Val Met 
    1940                 


<210>  3044
<211>  865
<212>  PRT
<213>  homo sapiens

<400>  3044

Met Ala Ser Leu Tyr Gln Arg Phe Thr Gly Lys Ile Asn Thr Ser Arg 
1               5                   10                  15      


Ser Phe Pro Ala Pro Pro Glu Ala Ser His Leu Leu Gly Gly Gln Gly 
            20                  25                  30          


Pro Glu Glu Asp Gly Gly Ala Gly Ala Lys Pro Leu Gly Pro Arg Ala 
        35                  40                  45              


Gln Ala Ala Ala Pro Arg Glu Arg Gly Gly Gly Gly Gly Gly Ala Gly 
    50                  55                  60                  


Gly Arg Pro Arg Phe Gln Tyr Gln Ala Arg Ser Asp Gly Asp Glu Glu 
65                  70                  75                  80  


Asp Glu Leu Val Gly Ser Asn Pro Pro Gln Arg Asn Trp Lys Gly Ile 
                85                  90                  95      


Ala Ile Ala Leu Leu Val Ile Leu Val Ile Cys Ser Leu Ile Val Thr 
            100                 105                 110         


Ser Val Ile Leu Leu Thr Pro Ala Glu Asp Asn Ser Leu Ser Gln Lys 
        115                 120                 125             


Lys Lys Val Thr Val Glu Asp Leu Phe Ser Glu Asp Phe Lys Ile His 
    130                 135                 140                 


Asp Pro Glu Ala Lys Trp Ile Ser Asp Thr Glu Phe Ile Tyr Arg Glu 
145                 150                 155                 160 


Gln Lys Gly Thr Val Arg Leu Trp Asn Val Glu Thr Asn Thr Ser Thr 
                165                 170                 175     


Val Leu Ile Glu Gly Lys Lys Ile Glu Ser Leu Arg Ala Ile Arg Tyr 
            180                 185                 190         


Glu Ile Ser Pro Asp Arg Glu Tyr Ala Leu Phe Ser Tyr Asn Val Glu 
        195                 200                 205             


Pro Ile Tyr Gln His Ser Tyr Thr Gly Tyr Tyr Val Leu Ser Lys Ile 
    210                 215                 220                 


Pro His Gly Asp Pro Gln Ser Leu Asp Pro Pro Glu Val Ser Asn Ala 
225                 230                 235                 240 


Lys Leu Gln Tyr Ala Gly Trp Gly Pro Lys Gly Gln Gln Leu Ile Phe 
                245                 250                 255     


Ile Phe Glu Asn Asn Ile Tyr Tyr Cys Ala His Val Gly Lys Gln Ala 
            260                 265                 270         


Ile Arg Val Val Ser Thr Gly Lys Glu Gly Val Ile Tyr Asn Gly Leu 
        275                 280                 285             


Ser Asp Trp Leu Tyr Glu Glu Glu Ile Leu Lys Thr His Ile Ala His 
    290                 295                 300                 


Trp Trp Ser Pro Asp Gly Thr Arg Leu Ala Tyr Ala Ala Ile Asn Asp 
305                 310                 315                 320 


Ser Arg Val Pro Ile Met Glu Leu Pro Thr Tyr Thr Gly Ser Ile Tyr 
                325                 330                 335     


Pro Thr Val Lys Pro Tyr His Tyr Pro Lys Ala Gly Ser Glu Asn Pro 
            340                 345                 350         


Ser Ile Ser Leu His Val Ile Gly Leu Asn Gly Pro Thr His Asp Leu 
        355                 360                 365             


Glu Met Met Pro Pro Asp Asp Pro Arg Met Arg Glu Tyr Tyr Ile Thr 
    370                 375                 380                 


Met Val Lys Trp Ala Thr Ser Thr Lys Val Ala Val Thr Trp Leu Asn 
385                 390                 395                 400 


Arg Ala Gln Asn Val Ser Ile Leu Thr Leu Cys Asp Ala Thr Thr Gly 
                405                 410                 415     


Val Cys Thr Lys Lys His Glu Asp Glu Ser Glu Ala Trp Leu His Arg 
            420                 425                 430         


Gln Asn Glu Glu Pro Val Phe Ser Lys Asp Gly Arg Lys Phe Phe Phe 
        435                 440                 445             


Ile Arg Ala Ile Pro Gln Gly Gly Arg Gly Lys Phe Tyr His Ile Thr 
    450                 455                 460                 


Val Ser Ser Ser Gln Pro Asn Ser Ser Asn Asp Asn Ile Gln Ser Ile 
465                 470                 475                 480 


Thr Ser Gly Asp Trp Asp Val Thr Lys Ile Leu Ala Tyr Asp Glu Lys 
                485                 490                 495     


Gly Asn Lys Ile Tyr Phe Leu Ser Thr Glu Asp Leu Pro Arg Arg Arg 
            500                 505                 510         


Gln Leu Tyr Ser Ala Asn Thr Val Gly Asn Phe Asn Arg Gln Cys Leu 
        515                 520                 525             


Ser Cys Asp Leu Val Glu Asn Cys Thr Tyr Phe Ser Ala Ser Phe Ser 
    530                 535                 540                 


His Ser Met Asp Phe Phe Leu Leu Lys Cys Glu Gly Pro Gly Val Pro 
545                 550                 555                 560 


Met Val Thr Val His Asn Thr Thr Asp Lys Lys Lys Met Phe Asp Leu 
                565                 570                 575     


Glu Thr Asn Glu His Val Lys Lys Ala Ile Asn Asp Arg Gln Met Pro 
            580                 585                 590         


Lys Val Glu Tyr Arg Asp Ile Glu Ile Asp Asp Tyr Asn Leu Pro Met 
        595                 600                 605             


Gln Ile Leu Lys Pro Ala Thr Phe Thr Asp Thr Thr His Tyr Pro Leu 
    610                 615                 620                 


Leu Leu Val Val Asp Gly Thr Pro Gly Ser Gln Ser Val Ala Glu Lys 
625                 630                 635                 640 


Phe Glu Val Ser Trp Glu Thr Val Met Val Ser Ser His Gly Ala Val 
                645                 650                 655     


Val Val Lys Cys Asp Gly Arg Gly Ser Gly Phe Gln Gly Thr Lys Leu 
            660                 665                 670         


Leu His Glu Val Arg Arg Arg Leu Gly Leu Leu Glu Glu Lys Asp Gln 
        675                 680                 685             


Met Glu Ala Val Arg Thr Met Leu Lys Glu Gln Tyr Ile Asp Arg Thr 
    690                 695                 700                 


Arg Val Ala Val Phe Gly Lys Asp Tyr Gly Gly Tyr Leu Ser Thr Tyr 
705                 710                 715                 720 


Ile Leu Pro Ala Lys Gly Glu Asn Gln Gly Gln Thr Phe Thr Cys Gly 
                725                 730                 735     


Ser Ala Leu Ser Pro Ile Thr Asp Phe Lys Leu Tyr Ala Ser Ala Phe 
            740                 745                 750         


Ser Glu Arg Tyr Leu Gly Leu His Gly Leu Asp Asn Arg Ala Tyr Glu 
        755                 760                 765             


Met Thr Lys Val Ala His Arg Val Ser Ala Leu Glu Glu Gln Gln Phe 
    770                 775                 780                 


Leu Ile Ile His Pro Thr Ala Asp Glu Lys Ile His Phe Gln His Thr 
785                 790                 795                 800 


Ala Glu Leu Ile Thr Gln Leu Ile Arg Gly Lys Ala Asn Tyr Ser Leu 
                805                 810                 815     


Gln Ile Tyr Pro Asp Glu Ser His Tyr Phe Thr Ser Ser Ser Leu Lys 
            820                 825                 830         


Gln His Leu Tyr Arg Ser Ile Ile Asn Phe Phe Val Glu Cys Phe Arg 
        835                 840                 845             


Ile Gln Asp Lys Leu Leu Thr Val Thr Ala Lys Glu Asp Glu Glu Glu 
    850                 855                 860                 


Asp 
865 


<210>  3045
<211>  462
<212>  PRT
<213>  homo sapiens

<400>  3045

Met Ala Ser Asn Ser Ser Ser Cys Pro Thr Pro Gly Gly Gly His Leu 
1               5                   10                  15      


Asn Gly Tyr Pro Val Pro Pro Tyr Ala Phe Phe Phe Pro Pro Met Leu 
            20                  25                  30          


Gly Gly Leu Ser Pro Pro Gly Ala Leu Thr Thr Leu Gln His Gln Leu 
        35                  40                  45              


Pro Val Ser Gly Tyr Ser Thr Pro Ser Pro Ala Thr Ile Glu Thr Gln 
    50                  55                  60                  


Ser Ser Ser Ser Glu Glu Ile Val Pro Ser Pro Pro Ser Pro Pro Pro 
65                  70                  75                  80  


Leu Pro Arg Ile Tyr Lys Pro Cys Phe Val Cys Gln Asp Lys Ser Ser 
                85                  90                  95      


Gly Tyr His Tyr Gly Val Ser Ala Cys Glu Gly Cys Lys Gly Phe Phe 
            100                 105                 110         


Arg Arg Ser Ile Gln Lys Asn Met Val Tyr Thr Cys His Arg Asp Lys 
        115                 120                 125             


Asn Cys Ile Ile Asn Lys Val Thr Arg Asn Arg Cys Gln Tyr Cys Arg 
    130                 135                 140                 


Leu Gln Lys Cys Phe Glu Val Gly Met Ser Lys Glu Ser Val Arg Asn 
145                 150                 155                 160 


Asp Arg Asn Lys Lys Lys Lys Glu Val Pro Lys Pro Glu Cys Ser Glu 
                165                 170                 175     


Ser Tyr Thr Leu Thr Pro Glu Val Gly Glu Leu Ile Glu Lys Val Arg 
            180                 185                 190         


Lys Ala His Gln Glu Thr Phe Pro Ala Leu Cys Gln Leu Gly Lys Tyr 
        195                 200                 205             


Thr Thr Asn Asn Ser Ser Glu Gln Arg Val Ser Leu Asp Ile Asp Leu 
    210                 215                 220                 


Trp Asp Lys Phe Ser Glu Leu Ser Thr Lys Cys Ile Ile Lys Thr Val 
225                 230                 235                 240 


Glu Phe Ala Lys Gln Leu Pro Gly Phe Thr Thr Leu Thr Ile Ala Asp 
                245                 250                 255     


Gln Ile Thr Leu Leu Lys Ala Ala Cys Leu Asp Ile Leu Ile Leu Arg 
            260                 265                 270         


Ile Cys Thr Arg Tyr Thr Pro Glu Gln Asp Thr Met Thr Phe Ser Asp 
        275                 280                 285             


Gly Leu Thr Leu Asn Arg Thr Gln Met His Asn Ala Gly Phe Gly Pro 
    290                 295                 300                 


Leu Thr Asp Leu Val Phe Ala Phe Ala Asn Gln Leu Leu Pro Leu Glu 
305                 310                 315                 320 


Met Asp Asp Ala Glu Thr Gly Leu Leu Ser Ala Ile Cys Leu Ile Cys 
                325                 330                 335     


Gly Asp Arg Gln Asp Leu Glu Gln Pro Asp Arg Val Asp Met Leu Gln 
            340                 345                 350         


Glu Pro Leu Leu Glu Ala Leu Lys Val Tyr Val Arg Lys Arg Arg Pro 
        355                 360                 365             


Ser Arg Pro His Met Phe Pro Lys Met Leu Met Lys Ile Thr Asp Leu 
    370                 375                 380                 


Arg Ser Ile Ser Ala Lys Gly Ala Glu Arg Val Ile Thr Leu Lys Met 
385                 390                 395                 400 


Glu Ile Pro Gly Ser Met Pro Pro Leu Ile Gln Glu Met Leu Glu Asn 
                405                 410                 415     


Ser Glu Gly Leu Asp Thr Leu Ser Gly Gln Pro Gly Gly Gly Gly Arg 
            420                 425                 430         


Asp Gly Gly Gly Leu Ala Pro Pro Pro Gly Ser Cys Ser Pro Ser Leu 
        435                 440                 445             


Ser Pro Ser Ser Asn Arg Ser Ser Pro Ala Thr His Ser Pro 
    450                 455                 460         


<210>  3046
<211>  664
<212>  PRT
<213>  homo sapiens

<400>  3046

Met Glu Gly Phe Met Asp Ser Gly Thr Gln Thr Asp Ala Val Val Val 
1               5                   10                  15      


Leu Ser Leu Ala Gln Ala Ala Val Leu Gly Leu Val Ser Glu Asn Glu 
            20                  25                  30          


Leu Phe Gly Ala Thr Ile Ser Ala Glu Ala Phe Tyr Pro Asp Leu Gly 
        35                  40                  45              


Pro Glu Leu Ser Gly Ala Ala Met Gly Glu Pro Glu Pro Pro Gly Pro 
    50                  55                  60                  


Asp Val Tyr Gln Leu Ala Cys Asn Gly Arg Ala Leu Glu Glu Pro Ala 
65                  70                  75                  80  


Glu Glu Glu Val Leu Glu Val Glu Ala Ala Cys Glu Lys His Thr Arg 
                85                  90                  95      


Arg Lys Thr Arg Pro Pro Val Arg Leu Val Pro Lys Val Lys Phe Glu 
            100                 105                 110         


Lys Val Glu Glu Glu Glu Gln Glu Val Tyr Glu Val Ser Val Pro Gly 
        115                 120                 125             


Asp Asp Lys Asp Ala Gly Pro Ala Glu Ala Pro Ala Glu Ala Ala Ser 
    130                 135                 140                 


Gly Gly Cys Asp Ala Leu Val Gln Ser Ser Ala Val Lys Met Ile Asp 
145                 150                 155                 160 


Leu Ser Ala Phe Ser Arg Lys Pro Arg Thr Leu Arg His Leu Pro Arg 
                165                 170                 175     


Thr Pro Arg Pro Glu Leu Asn Val Ala Pro Tyr Asp Pro His Phe Pro 
            180                 185                 190         


Ala Pro Ala Arg Asp Gly Phe Pro Glu Pro Ser Met Ala Leu Pro Gly 
        195                 200                 205             


Pro Glu Ala Leu Pro Thr Glu Cys Gly Phe Glu Pro Pro His Leu Ala 
    210                 215                 220                 


Pro Leu Ser Asp Pro Glu Ala Pro Ser Met Glu Ser Pro Glu Pro Val 
225                 230                 235                 240 


Lys Pro Glu Gln Gly Phe Val Trp Gln Glu Ala Ser Glu Phe Glu Ala 
                245                 250                 255     


Asp Thr Ala Gly Ser Thr Val Glu Arg His Lys Lys Ala Gln Leu Asp 
            260                 265                 270         


Arg Leu Asp Ile Asn Val Gln Ile Asp Asp Ser Tyr Leu Val Glu Ala 
        275                 280                 285             


Gly Asp Arg Gln Lys Arg Trp Gln Cys Arg Met Cys Glu Lys Ser Tyr 
    290                 295                 300                 


Thr Ser Lys Tyr Asn Leu Val Thr His Ile Leu Gly His Asn Gly Ile 
305                 310                 315                 320 


Lys Pro His Ser Cys Pro His Cys Ser Lys Leu Phe Lys Gln Pro Ser 
                325                 330                 335     


His Leu Gln Thr His Leu Leu Thr His Gln Gly Thr Arg Pro His Lys 
            340                 345                 350         


Cys Gln Val Cys His Lys Ala Phe Thr Gln Thr Ser His Leu Lys Arg 
        355                 360                 365             


His Met Leu Leu His Ser Glu Val Lys Pro Tyr Ser Cys His Phe Cys 
    370                 375                 380                 


Gly Arg Gly Phe Ala Tyr Pro Ser Glu Leu Lys Ala His Glu Val Lys 
385                 390                 395                 400 


His Glu Ser Gly Arg Cys His Val Cys Val Glu Cys Gly Leu Asp Phe 
                405                 410                 415     


Ser Thr Leu Thr Gln Leu Lys Arg His Leu Ala Ser His Gln Gly Pro 
            420                 425                 430         


Thr Leu Tyr Gln Cys Leu Glu Cys Asp Lys Ser Phe His Tyr Arg Ser 
        435                 440                 445             


Gln Leu Gln Asn His Met Leu Lys His Gln Asn Val Arg Pro Phe Val 
    450                 455                 460                 


Cys Thr Glu Cys Gly Met Glu Phe Ser Gln Ile His His Leu Lys Gln 
465                 470                 475                 480 


His Ser Leu Thr His Lys Gly Val Lys Glu Phe Lys Cys Glu Val Cys 
                485                 490                 495     


Gly Arg Glu Phe Thr Leu Gln Ala Asn Met Lys Arg His Met Leu Ile 
            500                 505                 510         


His Thr Ser Val Arg Pro Tyr Gln Cys His Ile Cys Phe Lys Thr Phe 
        515                 520                 525             


Val Gln Lys Gln Thr Leu Lys Thr His Met Ile Val His Ser Pro Val 
    530                 535                 540                 


Lys Pro Phe Lys Cys Lys Val Cys Gly Lys Ser Phe Asn Arg Met Tyr 
545                 550                 555                 560 


Asn Leu Leu Gly His Met His Leu His Ala Gly Ser Lys Pro Phe Lys 
                565                 570                 575     


Cys Pro Tyr Cys Ser Ser Lys Phe Asn Leu Lys Gly Asn Leu Ser Arg 
            580                 585                 590         


His Met Lys Val Lys His Gly Val Met Asp Ile Gly Leu Asp Ser Gln 
        595                 600                 605             


Asp Pro Met Met Glu Leu Thr Gly Thr Asp Pro Ser Glu Leu Asp Gly 
    610                 615                 620                 


Gln Gln Glu Met Glu Asp Phe Glu Glu Asn Ala Tyr Ser Tyr Ala Ser 
625                 630                 635                 640 


Val Asp Ser Ser Ala Glu Ala Ser Val Leu Thr Glu Gln Ala Met Lys 
                645                 650                 655     


Glu Met Ala Tyr Tyr Asn Val Leu 
            660                 


<210>  3047
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  3047

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Leu Gln Asp Leu 
1               5                   10                  15      


Arg Glu Asn Thr Glu Phe Thr Asp His Glu Leu Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Lys Asp Cys Pro Thr Gly His Leu Thr Val Asp Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Ala Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Thr Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Arg Ser Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Asp Lys Ile Phe Arg Gln Met Asp Thr Asn Asn 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Ser Gln 
            180                 185                 190         


Phe 
    


<210>  3048
<211>  1845
<212>  PRT
<213>  homo sapiens

<400>  3048

Met Gly Asp Val Lys Leu Val Ala Ser Ser His Ile Ser Lys Thr Ser 
1               5                   10                  15      


Leu Ser Val Asp Pro Ser Arg Val Asp Ser Met Pro Leu Thr Glu Ala 
            20                  25                  30          


Pro Ala Phe Ile Leu Pro Pro Arg Asn Leu Cys Ile Lys Glu Gly Ala 
        35                  40                  45              


Thr Ala Lys Phe Glu Gly Arg Val Arg Gly Tyr Pro Glu Pro Gln Val 
    50                  55                  60                  


Thr Trp His Arg Asn Gly Gln Pro Ile Thr Ser Gly Gly Arg Phe Leu 
65                  70                  75                  80  


Leu Asp Cys Gly Ile Arg Gly Thr Phe Ser Leu Val Ile His Ala Val 
                85                  90                  95      


His Glu Glu Asp Arg Gly Lys Tyr Thr Cys Glu Ala Thr Asn Gly Ser 
            100                 105                 110         


Gly Ala Arg Gln Val Thr Val Glu Leu Thr Val Glu Gly Ser Phe Ala 
        115                 120                 125             


Lys Gln Leu Gly Gln Pro Val Val Ser Lys Thr Leu Gly Asp Arg Phe 
    130                 135                 140                 


Ser Ala Pro Ala Val Glu Thr Arg Pro Ser Ile Trp Gly Glu Cys Pro 
145                 150                 155                 160 


Pro Lys Phe Ala Thr Lys Leu Gly Arg Val Val Val Lys Glu Gly Gln 
                165                 170                 175     


Met Gly Arg Phe Ser Cys Lys Ile Thr Gly Arg Pro Gln Pro Gln Val 
            180                 185                 190         


Thr Trp Leu Lys Gly Asn Val Pro Leu Gln Pro Ser Ala Arg Val Ser 
        195                 200                 205             


Val Ser Glu Lys Asn Gly Met Gln Val Leu Glu Ile His Gly Val Asn 
    210                 215                 220                 


Gln Asp Asp Val Gly Val Tyr Thr Cys Leu Val Val Asn Gly Ser Gly 
225                 230                 235                 240 


Lys Ala Ser Met Ser Ala Glu Leu Ser Ile Gln Gly Leu Asp Ser Ala 
                245                 250                 255     


Asn Arg Ser Phe Val Arg Glu Thr Lys Ala Thr Asn Ser Asp Val Arg 
            260                 265                 270         


Lys Glu Val Thr Asn Val Ile Ser Lys Glu Ser Lys Leu Asp Ser Leu 
        275                 280                 285             


Glu Ala Ala Ala Lys Ser Lys Asn Cys Ser Ser Pro Gln Arg Gly Gly 
    290                 295                 300                 


Ser Pro Pro Trp Ala Ala Asn Ser Gln Pro Gln Pro Pro Arg Glu Ser 
305                 310                 315                 320 


Lys Leu Glu Ser Cys Lys Asp Ser Pro Arg Thr Ala Pro Gln Thr Pro 
                325                 330                 335     


Val Leu Gln Lys Thr Ser Ser Ser Ile Thr Leu Gln Ala Ala Arg Val 
            340                 345                 350         


Gln Pro Glu Pro Arg Ala Pro Gly Leu Gly Val Leu Ser Pro Ser Gly 
        355                 360                 365             


Glu Glu Arg Lys Arg Pro Ala Pro Pro Arg Pro Ala Thr Phe Pro Thr 
    370                 375                 380                 


Arg Gln Pro Gly Leu Gly Ser Gln Asp Val Val Ser Lys Ala Ala Asn 
385                 390                 395                 400 


Arg Arg Ile Pro Met Glu Gly Gln Arg Asp Ser Ala Phe Pro Lys Phe 
                405                 410                 415     


Glu Ser Lys Pro Gln Ser Gln Glu Val Lys Glu Asn Gln Thr Val Lys 
            420                 425                 430         


Phe Arg Cys Glu Gly Leu Ala Val Met Glu Val Ala Pro Ser Phe Ser 
        435                 440                 445             


Ser Val Leu Lys Asp Cys Ala Val Ile Glu Gly Gln Asp Phe Val Leu 
    450                 455                 460                 


Gln Cys Ser Val Arg Gly Thr Pro Val Pro Arg Ile Thr Trp Leu Leu 
465                 470                 475                 480 


Asn Gly Gln Pro Ile Gln Tyr Ala Arg Ser Thr Cys Glu Ala Gly Val 
                485                 490                 495     


Ala Glu Leu His Ile Gln Asp Ala Leu Pro Glu Asp His Gly Thr Tyr 
            500                 505                 510         


Thr Cys Leu Ala Glu Asn Ala Leu Gly Gln Val Ser Cys Ser Ala Trp 
        515                 520                 525             


Val Thr Val His Glu Lys Lys Ser Ser Arg Lys Ser Glu Tyr Leu Leu 
    530                 535                 540                 


Pro Val Ala Pro Ser Lys Pro Thr Ala Pro Ile Phe Leu Gln Gly Leu 
545                 550                 555                 560 


Ser Asp Leu Lys Val Met Asp Gly Ser Gln Val Thr Met Thr Val Gln 
                565                 570                 575     


Val Ser Gly Asn Pro Pro Pro Glu Val Ile Trp Leu His Asn Gly Asn 
            580                 585                 590         


Glu Ile Gln Glu Ser Glu Asp Phe His Phe Glu Gln Arg Gly Thr Gln 
        595                 600                 605             


His Ser Leu Cys Ile Gln Glu Val Phe Pro Glu Asp Thr Gly Thr Tyr 
    610                 615                 620                 


Thr Cys Glu Ala Trp Asn Ser Ala Gly Glu Val Arg Thr Gln Ala Val 
625                 630                 635                 640 


Leu Thr Val Gln Glu Pro His Asp Gly Thr Gln Pro Trp Phe Ile Ser 
                645                 650                 655     


Lys Pro Arg Ser Val Thr Ala Ser Leu Gly Gln Ser Val Leu Ile Ser 
            660                 665                 670         


Cys Ala Ile Ala Gly Asp Pro Phe Pro Thr Val His Trp Leu Arg Asp 
        675                 680                 685             


Gly Lys Ala Leu Cys Lys Asp Thr Gly His Phe Glu Val Leu Gln Asn 
    690                 695                 700                 


Glu Asp Val Phe Thr Leu Val Leu Lys Lys Val Gln Pro Trp His Ala 
705                 710                 715                 720 


Gly Gln Tyr Glu Ile Leu Leu Lys Asn Arg Val Gly Glu Cys Ser Cys 
                725                 730                 735     


Gln Val Ser Leu Met Leu Gln Asn Ser Ser Ala Arg Ala Leu Pro Arg 
            740                 745                 750         


Gly Arg Glu Pro Ala Ser Cys Glu Asp Leu Cys Gly Gly Gly Val Gly 
        755                 760                 765             


Ala Asp Gly Gly Gly Ser Asp Arg Tyr Gly Ser Leu Arg Pro Gly Trp 
    770                 775                 780                 


Pro Ala Arg Gly Gln Gly Trp Leu Glu Glu Glu Asp Gly Glu Asp Val 
785                 790                 795                 800 


Arg Gly Val Leu Lys Arg Arg Val Glu Thr Arg Gln His Thr Glu Glu 
                805                 810                 815     


Ala Ile Arg Gln Gln Glu Val Glu Gln Leu Asp Phe Arg Asp Leu Leu 
            820                 825                 830         


Gly Lys Lys Val Ser Thr Lys Thr Leu Ser Glu Asp Asp Leu Lys Glu 
        835                 840                 845             


Ile Pro Ala Glu Gln Met Asp Phe Arg Ala Asn Leu Gln Arg Gln Val 
    850                 855                 860                 


Lys Pro Lys Thr Val Ser Glu Glu Glu Arg Lys Val His Ser Pro Gln 
865                 870                 875                 880 


Gln Val Asp Phe Arg Ser Val Leu Ala Lys Lys Gly Thr Ser Lys Thr 
                885                 890                 895     


Pro Val Pro Glu Lys Val Pro Pro Pro Lys Pro Ala Thr Pro Asp Phe 
            900                 905                 910         


Arg Ser Val Leu Gly Gly Lys Lys Lys Leu Pro Ala Glu Asn Gly Ser 
        915                 920                 925             


Ser Ser Ala Glu Thr Leu Asn Ala Lys Ala Val Glu Ser Ser Lys Pro 
    930                 935                 940                 


Leu Ser Asn Ala Gln Pro Ser Gly Pro Leu Lys Pro Val Gly Asn Ala 
945                 950                 955                 960 


Lys Pro Ala Glu Thr Leu Lys Pro Met Gly Asn Ala Lys Pro Ala Glu 
                965                 970                 975     


Thr Leu Lys Pro Met Gly Asn Ala Lys Pro Asp Glu Asn Leu Lys Ser 
            980                 985                 990         


Ala Ser Lys Glu Glu Leu Lys Lys  Asp Val Lys Asn Asp  Val Asn Cys 
        995                 1000                 1005             


Lys Arg  Gly His Ala Gly Thr  Thr Asp Asn Glu Lys  Arg Ser Glu 
    1010                 1015                 1020             


Ser Gln  Gly Thr Ala Pro Ala  Phe Lys Gln Lys Leu  Gln Asp Val 
    1025                 1030                 1035             


His Val  Ala Glu Gly Lys Lys  Leu Leu Leu Gln Cys  Gln Val Ser 
    1040                 1045                 1050             


Ser Asp  Pro Pro Ala Thr Ile  Ile Trp Thr Leu Asn  Gly Lys Thr 
    1055                 1060                 1065             


Leu Lys  Thr Thr Lys Phe Ile  Ile Leu Ser Gln Glu  Gly Ser Leu 
    1070                 1075                 1080             


Cys Ser  Val Ser Ile Glu Lys  Ala Leu Pro Glu Asp  Arg Gly Leu 
    1085                 1090                 1095             


Tyr Lys  Cys Val Ala Lys Asn  Asp Ala Gly Gln Ala  Glu Cys Ser 
    1100                 1105                 1110             


Cys Gln  Val Thr Val Asp Asp  Ala Pro Ala Ser Glu  Asn Thr Lys 
    1115                 1120                 1125             


Ala Pro  Glu Met Lys Ser Arg  Arg Pro Lys Ser Ser  Leu Pro Pro 
    1130                 1135                 1140             


Val Leu  Gly Thr Glu Ser Asp  Ala Thr Val Lys Lys  Lys Pro Ala 
    1145                 1150                 1155             


Pro Lys  Thr Pro Pro Lys Ala  Ala Met Pro Pro Gln  Ile Ile Gln 
    1160                 1165                 1170             


Phe Pro  Glu Asp Gln Lys Val  Arg Ala Gly Glu Ser  Val Glu Leu 
    1175                 1180                 1185             


Phe Gly  Lys Val Thr Gly Thr  Gln Pro Ile Thr Cys  Thr Trp Met 
    1190                 1195                 1200             


Lys Phe  Arg Lys Gln Ile Gln  Glu Ser Glu His Met  Lys Val Glu 
    1205                 1210                 1215             


Asn Ser  Glu Asn Gly Ser Lys  Leu Thr Ile Leu Ala  Ala Arg Gln 
    1220                 1225                 1230             


Glu His  Cys Gly Cys Tyr Thr  Leu Leu Val Glu Asn  Lys Leu Gly 
    1235                 1240                 1245             


Ser Arg  Gln Ala Gln Val Asn  Leu Thr Val Val Asp  Lys Pro Asp 
    1250                 1255                 1260             


Pro Pro  Ala Gly Thr Pro Cys  Ala Ser Asp Ile Arg  Ser Ser Ser 
    1265                 1270                 1275             


Leu Thr  Leu Ser Trp Tyr Gly  Ser Ser Tyr Asp Gly  Gly Ser Ala 
    1280                 1285                 1290             


Val Gln  Ser Tyr Ser Ile Glu  Ile Trp Asp Ser Ala  Asn Lys Thr 
    1295                 1300                 1305             


Trp Lys  Glu Leu Ala Thr Cys  Arg Ser Thr Ser Phe  Asn Val Gln 
    1310                 1315                 1320             


Asp Leu  Leu Pro Asp His Glu  Tyr Lys Phe Arg Val  Arg Ala Ile 
    1325                 1330                 1335             


Asn Val  Tyr Gly Thr Ser Glu  Pro Ser Gln Glu Ser  Glu Leu Thr 
    1340                 1345                 1350             


Thr Val  Gly Glu Lys Pro Glu  Glu Pro Lys Asp Glu  Val Glu Val 
    1355                 1360                 1365             


Ser Asp  Asp Asp Glu Lys Glu  Pro Glu Val Asp Tyr  Arg Thr Val 
    1370                 1375                 1380             


Thr Ile  Asn Thr Glu Gln Lys  Val Ser Asp Phe Tyr  Asp Ile Glu 
    1385                 1390                 1395             


Glu Arg  Leu Gly Ser Gly Lys  Phe Gly Gln Val Phe  Arg Leu Val 
    1400                 1405                 1410             


Glu Lys  Lys Thr Arg Lys Val  Trp Ala Gly Lys Phe  Phe Lys Ala 
    1415                 1420                 1425             


Tyr Ser  Ala Lys Glu Lys Glu  Asn Ile Arg Gln Glu  Ile Ser Ile 
    1430                 1435                 1440             


Met Asn  Cys Leu His His Pro  Lys Leu Val Gln Cys  Val Asp Ala 
    1445                 1450                 1455             


Phe Glu  Glu Lys Ala Asn Ile  Val Met Val Leu Glu  Ile Val Ser 
    1460                 1465                 1470             


Gly Gly  Glu Leu Phe Glu Arg  Ile Ile Asp Glu Asp  Phe Glu Leu 
    1475                 1480                 1485             


Thr Glu  Arg Glu Cys Ile Lys  Tyr Met Arg Gln Ile  Ser Glu Gly 
    1490                 1495                 1500             


Val Glu  Tyr Ile His Lys Gln  Gly Ile Val His Leu  Asp Leu Lys 
    1505                 1510                 1515             


Pro Glu  Asn Ile Met Cys Val  Asn Lys Thr Gly Thr  Arg Ile Lys 
    1520                 1525                 1530             


Leu Ile  Asp Phe Gly Leu Ala  Arg Arg Leu Glu Asn  Ala Gly Ser 
    1535                 1540                 1545             


Leu Lys  Val Leu Phe Gly Thr  Pro Glu Phe Val Ala  Pro Glu Val 
    1550                 1555                 1560             


Ile Asn  Tyr Glu Pro Ile Gly  Tyr Ala Thr Asp Met  Trp Ser Ile 
    1565                 1570                 1575             


Gly Val  Ile Cys Tyr Ile Leu  Val Ser Gly Leu Ser  Pro Phe Met 
    1580                 1585                 1590             


Gly Asp  Asn Asp Asn Glu Thr  Leu Ala Asn Val Thr  Ser Ala Thr 
    1595                 1600                 1605             


Trp Asp  Phe Asp Asp Glu Ala  Phe Asp Glu Ile Ser  Asp Asp Ala 
    1610                 1615                 1620             


Lys Asp  Phe Ile Ser Asn Leu  Leu Lys Lys Asp Met  Lys Asn Arg 
    1625                 1630                 1635             


Leu Asp  Cys Thr Gln Cys Leu  Gln His Pro Trp Leu  Met Lys Asp 
    1640                 1645                 1650             


Thr Lys  Asn Met Glu Ala Lys  Lys Leu Ser Lys Asp  Arg Met Lys 
    1655                 1660                 1665             


Lys Tyr  Met Ala Arg Arg Lys  Trp Gln Lys Thr Gly  Asn Ala Val 
    1670                 1675                 1680             


Arg Ala  Ile Gly Arg Leu Ser  Ser Met Ala Met Ile  Ser Gly Leu 
    1685                 1690                 1695             


Ser Gly  Arg Lys Ser Ser Thr  Gly Ser Pro Thr Ser  Pro Leu Asn 
    1700                 1705                 1710             


Ala Glu  Lys Leu Glu Ser Glu  Glu Asp Val Ser Gln  Ala Phe Leu 
    1715                 1720                 1725             


Glu Ala  Val Ala Glu Glu Lys  Pro His Val Lys Pro  Tyr Phe Ser 
    1730                 1735                 1740             


Lys Thr  Ile Arg Asp Leu Glu  Val Val Glu Gly Ser  Ala Ala Arg 
    1745                 1750                 1755             


Phe Asp  Cys Lys Ile Glu Gly  Tyr Pro Asp Pro Glu  Val Val Trp 
    1760                 1765                 1770             


Phe Lys  Asp Asp Gln Ser Ile  Arg Glu Ser Arg His  Phe Gln Ile 
    1775                 1780                 1785             


Asp Tyr  Asp Glu Asp Gly Asn  Cys Ser Leu Ile Ile  Ser Asp Val 
    1790                 1795                 1800             


Cys Gly  Asp Asp Asp Ala Lys  Tyr Thr Cys Lys Ala  Val Asn Ser 
    1805                 1810                 1815             


Leu Gly  Glu Ala Thr Cys Thr  Ala Glu Leu Ile Val  Glu Thr Met 
    1820                 1825                 1830             


Glu Glu  Gly Glu Gly Glu Gly  Glu Glu Glu Glu Glu  
    1835                 1840                 1845 


<210>  3049
<211>  274
<212>  PRT
<213>  homo sapiens

<400>  3049

Met Thr Lys Ser Cys Ser Glu Leu Cys His Pro Ala Leu His Phe Leu 
1               5                   10                  15      


Pro Cys Leu Gly Gly Leu Arg Lys Asn Leu Gln Arg Ala Val Arg Pro 
            20                  25                  30          


Ser Pro Tyr Ser Leu Gly Phe Leu Thr Phe Trp Ile Ser Arg Val Glu 
        35                  40                  45              


Lys Asn Asp Asp Asp Gln Lys Ile Glu Gln Asp Gly Ile Lys Pro Glu 
    50                  55                  60                  


Asp Lys Ala His Lys Ala Ala Thr Lys Ile Gln Ala Ser Phe Arg Gly 
65                  70                  75                  80  


His Ile Thr Arg Lys Lys Leu Lys Gly Glu Lys Lys Asp Asp Val Gln 
                85                  90                  95      


Ala Ala Glu Ala Glu Ala Asn Lys Lys Asp Glu Ala Pro Val Ala Asp 
            100                 105                 110         


Gly Val Glu Lys Lys Gly Glu Gly Thr Thr Thr Ala Glu Ala Ala Pro 
        115                 120                 125             


Ala Thr Gly Ser Lys Pro Asp Glu Pro Gly Lys Ala Gly Glu Thr Pro 
    130                 135                 140                 


Ser Glu Glu Lys Lys Gly Glu Gly Asp Ala Ala Thr Glu Gln Ala Ala 
145                 150                 155                 160 


Pro Gln Ala Pro Ala Ser Ser Glu Glu Lys Ala Gly Ser Ala Glu Thr 
                165                 170                 175     


Glu Ser Ala Thr Lys Ala Ser Thr Asp Asn Ser Pro Ser Ser Lys Ala 
            180                 185                 190         


Glu Asp Ala Pro Ala Lys Glu Glu Pro Lys Gln Ala Asp Val Pro Ala 
        195                 200                 205             


Ala Val Thr Ala Ala Ala Ala Thr Thr Pro Ala Ala Glu Asp Ala Ala 
    210                 215                 220                 


Ala Lys Ala Thr Ala Gln Pro Pro Thr Glu Thr Gly Glu Ser Ser Gln 
225                 230                 235                 240 


Ala Glu Glu Asn Ile Glu Ala Val Asp Glu Thr Lys Pro Lys Glu Ser 
                245                 250                 255     


Ala Arg Gln Asp Glu Gly Lys Glu Glu Glu Pro Glu Ala Asp Gln Glu 
            260                 265                 270         


His Ala 
        


<210>  3050
<211>  268
<212>  PRT
<213>  homo sapiens

<400>  3050

Met Thr Thr Asp Glu Gly Ala Lys Asn Asn Glu Glu Ser Pro Thr Ala 
1               5                   10                  15      


Thr Val Ala Glu Gln Gly Glu Asp Ile Thr Ser Lys Lys Asp Arg Gly 
            20                  25                  30          


Val Leu Lys Ile Val Lys Arg Val Gly Asn Gly Glu Glu Thr Pro Met 
        35                  40                  45              


Ile Gly Asp Lys Val Tyr Val His Tyr Lys Gly Lys Leu Ser Asn Gly 
    50                  55                  60                  


Lys Lys Phe Asp Ser Ser His Asp Arg Asn Glu Pro Phe Val Phe Ser 
65                  70                  75                  80  


Leu Gly Lys Gly Gln Val Ile Lys Ala Trp Asp Ile Gly Val Ala Thr 
                85                  90                  95      


Met Lys Lys Gly Glu Ile Cys His Leu Leu Cys Lys Pro Glu Tyr Ala 
            100                 105                 110         


Tyr Gly Ser Ala Gly Ser Leu Pro Lys Ile Pro Ser Asn Ala Thr Leu 
        115                 120                 125             


Phe Phe Glu Ile Glu Leu Leu Asp Phe Lys Gly Glu Asp Leu Phe Glu 
    130                 135                 140                 


Asp Gly Gly Ile Ile Arg Arg Thr Lys Arg Lys Gly Glu Gly Tyr Ser 
145                 150                 155                 160 


Asn Pro Asn Glu Gly Ala Thr Val Glu Ile His Leu Glu Gly Arg Cys 
                165                 170                 175     


Gly Gly Arg Met Phe Asp Cys Arg Asp Val Ala Phe Thr Val Gly Glu 
            180                 185                 190         


Gly Glu Asp His Asp Ile Pro Ile Gly Ile Asp Lys Ala Leu Glu Lys 
        195                 200                 205             


Met Gln Arg Glu Glu Gln Cys Ile Leu Tyr Leu Gly Pro Arg Pro Lys 
    210                 215                 220                 


Asn Pro Gly Arg Trp Ile Pro Lys Lys Asn Trp Ser Arg Leu Pro Leu 
225                 230                 235                 240 


Ser Lys Arg Arg Glu Pro Tyr Thr Ser Arg Cys Val Ser Pro Tyr Ala 
                245                 250                 255     


Ile Leu Ser Ile Ser Lys Asn Leu Phe Lys Cys Trp 
            260                 265             


<210>  3051
<211>  233
<212>  PRT
<213>  homo sapiens

<400>  3051

Met Ala Gly Val Arg Ser Leu Arg Cys Ser Arg Gly Cys Ala Gly Gly 
1               5                   10                  15      


Cys Glu Cys Gly Asp Lys Gly Lys Cys Ser Asp Ser Ser Leu Leu Gly 
            20                  25                  30          


Lys Arg Leu Ser Glu Asp Ser Ser Arg His Gln Leu Leu Gln Lys Trp 
        35                  40                  45              


Ala Ser Met Trp Ser Ser Met Ser Glu Asp Ala Ser Val Ala Asp Met 
    50                  55                  60                  


Glu Arg Ala Gln Leu Glu Glu Glu Ala Ala Ala Ala Glu Glu Arg Pro 
65                  70                  75                  80  


Leu Val Phe Leu Cys Ser Gly Cys Arg Arg Pro Leu Gly Asp Ser Leu 
                85                  90                  95      


Ser Trp Val Ala Ser Gln Glu Asp Thr Asn Cys Ile Leu Leu Arg Cys 
            100                 105                 110         


Val Ser Cys Asn Val Ser Val Asp Lys Glu Gln Lys Leu Ser Lys Arg 
        115                 120                 125             


Glu Lys Glu Asn Gly Cys Val Leu Glu Thr Leu Cys Cys Ala Gly Cys 
    130                 135                 140                 


Ser Leu Asn Leu Gly Tyr Val Tyr Arg Cys Thr Pro Lys Asn Leu Asp 
145                 150                 155                 160 


Tyr Lys Arg Asp Leu Phe Cys Leu Ser Val Glu Ala Ile Glu Ser Tyr 
                165                 170                 175     


Val Leu Gly Ser Ser Glu Lys Gln Ile Val Ser Glu Asp Lys Glu Leu 
            180                 185                 190         


Phe Asn Leu Glu Ser Arg Val Glu Ile Glu Lys Ser Leu Thr Gln Met 
        195                 200                 205             


Glu Asp Val Leu Lys Ala Leu Gln Met Lys Leu Trp Glu Ala Glu Ser 
    210                 215                 220                 


Lys Leu Ser Phe Ala Thr Cys Lys Ser 
225                 230             


<210>  3052
<211>  2000
<212>  PRT
<213>  homo sapiens

<400>  3052

Met Ala Gln Ala Leu Leu Val Pro Pro Gly Pro Glu Ser Phe Arg Leu 
1               5                   10                  15      


Phe Thr Arg Glu Ser Leu Ala Ala Ile Glu Lys Arg Ala Ala Glu Glu 
            20                  25                  30          


Lys Ala Lys Lys Pro Lys Lys Glu Gln Asp Asn Asp Asp Glu Asn Lys 
        35                  40                  45              


Pro Lys Pro Asn Ser Asp Leu Glu Ala Gly Lys Asn Leu Pro Phe Ile 
    50                  55                  60                  


Tyr Gly Asp Ile Pro Pro Glu Met Val Ser Glu Pro Leu Glu Asp Leu 
65                  70                  75                  80  


Asp Pro Tyr Tyr Ile Asn Lys Lys Thr Phe Ile Val Met Asn Lys Gly 
                85                  90                  95      


Lys Ala Ile Phe Arg Phe Ser Ala Thr Ser Ala Leu Tyr Ile Leu Thr 
            100                 105                 110         


Pro Leu Asn Pro Val Arg Lys Ile Ala Ile Lys Ile Leu Val His Ser 
        115                 120                 125             


Leu Phe Ser Met Leu Ile Met Cys Thr Ile Leu Thr Asn Cys Val Phe 
    130                 135                 140                 


Met Thr Leu Ser Asn Pro Pro Asp Trp Thr Lys Asn Val Glu Tyr Thr 
145                 150                 155                 160 


Phe Thr Gly Ile Tyr Thr Phe Glu Ser Leu Ile Lys Ile Leu Ala Arg 
                165                 170                 175     


Gly Phe Cys Leu Glu Asp Phe Thr Phe Leu Arg Asp Pro Trp Asn Trp 
            180                 185                 190         


Leu Asp Phe Ser Val Ile Val Met Ala Tyr Val Thr Glu Phe Val Asp 
        195                 200                 205             


Leu Gly Asn Val Ser Ala Leu Arg Thr Phe Arg Val Leu Arg Ala Leu 
    210                 215                 220                 


Lys Thr Ile Ser Val Ile Pro Gly Leu Lys Thr Ile Val Gly Ala Leu 
225                 230                 235                 240 


Ile Gln Ser Val Lys Lys Leu Ser Asp Val Met Ile Leu Thr Val Phe 
                245                 250                 255     


Cys Leu Ser Val Phe Ala Leu Ile Gly Leu Gln Leu Phe Met Gly Asn 
            260                 265                 270         


Leu Arg Asn Lys Cys Leu Gln Trp Pro Pro Ser Asp Ser Ala Phe Glu 
        275                 280                 285             


Thr Asn Thr Thr Ser Tyr Phe Asn Gly Thr Met Asp Ser Asn Gly Thr 
    290                 295                 300                 


Phe Val Asn Val Thr Met Ser Thr Phe Asn Trp Lys Asp Tyr Ile Gly 
305                 310                 315                 320 


Asp Asp Ser His Phe Tyr Val Leu Asp Gly Gln Lys Asp Pro Leu Leu 
                325                 330                 335     


Cys Gly Asn Gly Ser Asp Ala Gly Gln Cys Pro Glu Gly Tyr Ile Cys 
            340                 345                 350         


Val Lys Ala Gly Arg Asn Pro Asn Tyr Gly Tyr Thr Ser Phe Asp Thr 
        355                 360                 365             


Phe Ser Trp Ala Phe Leu Ser Leu Phe Arg Leu Met Thr Gln Asp Tyr 
    370                 375                 380                 


Trp Glu Asn Leu Tyr Gln Leu Thr Leu Arg Ala Ala Gly Lys Thr Tyr 
385                 390                 395                 400 


Met Ile Phe Phe Val Leu Val Ile Phe Leu Gly Ser Phe Tyr Leu Val 
                405                 410                 415     


Asn Leu Ile Leu Ala Val Val Ala Met Ala Tyr Glu Glu Gln Asn Gln 
            420                 425                 430         


Ala Thr Leu Glu Glu Ala Glu Gln Lys Glu Ala Glu Phe Gln Gln Met 
        435                 440                 445             


Leu Glu Gln Leu Lys Lys Gln Gln Glu Glu Ala Gln Ala Val Ala Ala 
    450                 455                 460                 


Ala Ser Ala Ala Ser Arg Asp Phe Ser Gly Ile Gly Gly Leu Gly Glu 
465                 470                 475                 480 


Leu Leu Glu Ser Ser Ser Glu Ala Ser Lys Leu Ser Ser Lys Ser Ala 
                485                 490                 495     


Lys Glu Trp Arg Asn Arg Arg Lys Lys Arg Arg Gln Arg Glu His Leu 
            500                 505                 510         


Glu Gly Asn Asn Lys Gly Glu Arg Asp Ser Phe Pro Lys Ser Glu Ser 
        515                 520                 525             


Glu Asp Ser Val Lys Arg Ser Ser Phe Leu Phe Ser Met Asp Gly Asn 
    530                 535                 540                 


Arg Leu Thr Ser Asp Lys Lys Phe Cys Ser Pro His Gln Ser Leu Leu 
545                 550                 555                 560 


Ser Ile Arg Gly Ser Leu Phe Ser Pro Arg Arg Asn Ser Lys Thr Ser 
                565                 570                 575     


Ile Phe Ser Phe Arg Gly Arg Ala Lys Asp Val Gly Ser Glu Asn Asp 
            580                 585                 590         


Phe Ala Asp Asp Glu His Ser Thr Phe Glu Asp Ser Glu Ser Arg Arg 
        595                 600                 605             


Asp Ser Leu Phe Val Pro His Arg His Gly Glu Arg Arg Asn Ser Asn 
    610                 615                 620                 


Val Ser Gln Ala Ser Met Ser Ser Arg Met Val Pro Gly Leu Pro Ala 
625                 630                 635                 640 


Asn Gly Lys Met His Ser Thr Val Asp Cys Asn Gly Val Val Ser Leu 
                645                 650                 655     


Val Gly Gly Pro Ser Ala Leu Thr Ser Pro Thr Gly Gln Leu Pro Pro 
            660                 665                 670         


Glu Gly Thr Thr Thr Glu Thr Glu Val Arg Lys Arg Arg Leu Ser Ser 
        675                 680                 685             


Tyr Gln Ile Ser Met Glu Met Leu Glu Asp Ser Ser Gly Arg Gln Arg 
    690                 695                 700                 


Ala Val Ser Ile Ala Ser Ile Leu Thr Asn Thr Met Glu Glu Leu Glu 
705                 710                 715                 720 


Glu Ser Arg Gln Lys Cys Pro Pro Cys Trp Tyr Arg Phe Ala Asn Val 
                725                 730                 735     


Phe Leu Ile Trp Asp Cys Cys Asp Ala Trp Leu Lys Val Lys His Leu 
            740                 745                 750         


Val Asn Leu Ile Val Met Asp Pro Phe Val Asp Leu Ala Ile Thr Ile 
        755                 760                 765             


Cys Ile Val Leu Asn Thr Leu Phe Met Ala Met Glu His Tyr Pro Met 
    770                 775                 780                 


Thr Glu Gln Phe Ser Ser Val Leu Thr Val Gly Asn Leu Val Phe Thr 
785                 790                 795                 800 


Gly Ile Phe Thr Ala Glu Met Val Leu Lys Ile Ile Ala Met Asp Pro 
                805                 810                 815     


Tyr Tyr Tyr Phe Gln Glu Gly Trp Asn Ile Phe Asp Gly Ile Ile Val 
            820                 825                 830         


Ser Leu Ser Leu Met Glu Leu Gly Leu Ser Asn Val Glu Gly Leu Ser 
        835                 840                 845             


Val Leu Arg Ser Phe Arg Leu Leu Arg Val Phe Lys Leu Ala Lys Ser 
    850                 855                 860                 


Trp Pro Thr Leu Asn Met Leu Ile Lys Ile Ile Gly Asn Ser Val Gly 
865                 870                 875                 880 


Ala Leu Gly Asn Leu Thr Leu Val Leu Ala Ile Ile Val Phe Ile Phe 
                885                 890                 895     


Ala Val Val Gly Met Gln Leu Phe Gly Lys Ser Tyr Lys Glu Cys Val 
            900                 905                 910         


Cys Lys Ile Asn Asp Asp Cys Thr Leu Pro Arg Trp His Met Asn Asp 
        915                 920                 925             


Phe Phe His Ser Phe Leu Ile Val Phe Arg Val Leu Cys Gly Glu Trp 
    930                 935                 940                 


Ile Glu Thr Met Trp Asp Cys Met Glu Val Ala Gly Gln Thr Met Cys 
945                 950                 955                 960 


Leu Ile Val Phe Met Leu Val Met Val Ile Gly Asn Leu Val Val Leu 
                965                 970                 975     


Asn Leu Phe Leu Ala Leu Leu Leu Ser Ser Phe Ser Ser Asp Asn Leu 
            980                 985                 990         


Ala Ala Thr Asp Asp Asp Asn Glu  Met Asn Asn Leu Gln  Ile Ala Val 
        995                 1000                 1005             


Gly Arg  Met Gln Lys Gly Ile  Asp Tyr Val Lys Asn  Lys Met Arg 
    1010                 1015                 1020             


Glu Cys  Phe Gln Lys Ala Phe  Phe Arg Lys Pro Lys  Val Ile Glu 
    1025                 1030                 1035             


Ile His  Glu Gly Asn Lys Ile  Asp Ser Cys Met Ser  Asn Asn Thr 
    1040                 1045                 1050             


Gly Ile  Glu Ile Ser Lys Glu  Leu Asn Tyr Leu Arg  Asp Gly Asn 
    1055                 1060                 1065             


Gly Thr  Thr Ser Gly Val Gly  Thr Gly Ser Ser Val  Glu Lys Tyr 
    1070                 1075                 1080             


Val Ile  Asp Glu Asn Asp Tyr  Met Ser Phe Ile Asn  Asn Pro Ser 
    1085                 1090                 1095             


Leu Thr  Val Thr Val Pro Ile  Ala Val Gly Glu Ser  Asp Phe Glu 
    1100                 1105                 1110             


Asn Leu  Asn Thr Glu Glu Phe  Ser Ser Glu Ser Glu  Leu Glu Glu 
    1115                 1120                 1125             


Ser Lys  Glu Lys Leu Asn Ala  Thr Ser Ser Ser Glu  Gly Ser Thr 
    1130                 1135                 1140             


Val Asp  Val Val Leu Pro Arg  Glu Gly Glu Gln Ala  Glu Thr Glu 
    1145                 1150                 1155             


Pro Glu  Glu Asp Leu Lys Pro  Glu Ala Cys Phe Thr  Glu Gly Cys 
    1160                 1165                 1170             


Ile Lys  Lys Phe Pro Phe Cys  Gln Val Ser Thr Glu  Glu Gly Lys 
    1175                 1180                 1185             


Gly Lys  Ile Trp Trp Asn Leu  Arg Lys Thr Cys Tyr  Ser Ile Val 
    1190                 1195                 1200             


Glu His  Asn Trp Phe Glu Thr  Phe Ile Val Phe Met  Ile Leu Leu 
    1205                 1210                 1215             


Ser Ser  Gly Ala Leu Ala Phe  Glu Asp Ile Tyr Ile  Glu Gln Arg 
    1220                 1225                 1230             


Lys Thr  Ile Lys Thr Met Leu  Glu Tyr Ala Asp Lys  Val Phe Thr 
    1235                 1240                 1245             


Tyr Ile  Phe Ile Leu Glu Met  Leu Leu Lys Trp Val  Ala Tyr Gly 
    1250                 1255                 1260             


Phe Gln  Thr Tyr Phe Thr Asn  Ala Trp Cys Trp Leu  Asp Phe Leu 
    1265                 1270                 1275             


Ile Val  Asp Val Ser Leu Val  Ser Leu Val Ala Asn  Ala Leu Gly 
    1280                 1285                 1290             


Tyr Ser  Glu Leu Gly Ala Ile  Lys Ser Leu Arg Thr  Leu Arg Ala 
    1295                 1300                 1305             


Leu Arg  Pro Leu Arg Ala Leu  Ser Arg Phe Glu Gly  Met Arg Val 
    1310                 1315                 1320             


Val Val  Asn Ala Leu Val Gly  Ala Ile Pro Ser Ile  Met Asn Val 
    1325                 1330                 1335             


Leu Leu  Val Cys Leu Ile Phe  Trp Leu Ile Phe Ser  Ile Met Gly 
    1340                 1345                 1350             


Val Asn  Leu Phe Ala Gly Lys  Phe Tyr His Cys Val  Asn Met Thr 
    1355                 1360                 1365             


Thr Gly  Asn Met Phe Asp Ile  Ser Asp Val Asn Asn  Leu Ser Asp 
    1370                 1375                 1380             


Cys Gln  Ala Leu Gly Lys Gln  Ala Arg Trp Lys Asn  Val Lys Val 
    1385                 1390                 1395             


Asn Phe  Asp Asn Val Gly Ala  Gly Tyr Leu Ala Leu  Leu Gln Val 
    1400                 1405                 1410             


Ala Thr  Phe Lys Gly Trp Met  Asp Ile Met Tyr Ala  Ala Val Asp 
    1415                 1420                 1425             


Ser Arg  Asp Val Lys Leu Gln  Pro Val Tyr Glu Glu  Asn Leu Tyr 
    1430                 1435                 1440             


Met Tyr  Leu Tyr Phe Val Ile  Phe Ile Ile Phe Gly  Ser Phe Phe 
    1445                 1450                 1455             


Thr Leu  Asn Leu Phe Ile Gly  Val Ile Ile Asp Asn  Phe Asn Gln 
    1460                 1465                 1470             


Gln Lys  Lys Lys Phe Gly Gly  Gln Asp Ile Phe Met  Thr Glu Glu 
    1475                 1480                 1485             


Gln Lys  Lys Tyr Tyr Asn Ala  Met Lys Lys Leu Gly  Ser Lys Lys 
    1490                 1495                 1500             


Pro Gln  Lys Pro Ile Pro Arg  Pro Ala Asn Lys Phe  Gln Gly Met 
    1505                 1510                 1515             


Val Phe  Asp Phe Val Thr Arg  Gln Val Phe Asp Ile  Ser Ile Met 
    1520                 1525                 1530             


Ile Leu  Ile Cys Leu Asn Met  Val Thr Met Met Val  Glu Thr Asp 
    1535                 1540                 1545             


Asp Gln  Gly Lys Tyr Met Thr  Leu Val Leu Ser Arg  Ile Asn Leu 
    1550                 1555                 1560             


Val Phe  Ile Val Leu Phe Thr  Gly Glu Phe Val Leu  Lys Leu Val 
    1565                 1570                 1575             


Ser Leu  Arg His Tyr Tyr Phe  Thr Ile Gly Trp Asn  Ile Phe Asp 
    1580                 1585                 1590             


Phe Val  Val Val Ile Leu Ser  Ile Val Gly Met Phe  Leu Ala Glu 
    1595                 1600                 1605             


Met Ile  Glu Lys Tyr Phe Val  Ser Pro Thr Leu Phe  Arg Val Ile 
    1610                 1615                 1620             


Arg Leu  Ala Arg Ile Gly Arg  Ile Leu Arg Leu Ile  Lys Gly Ala 
    1625                 1630                 1635             


Lys Gly  Ile Arg Thr Leu Leu  Phe Ala Leu Met Met  Ser Leu Pro 
    1640                 1645                 1650             


Ala Leu  Phe Asn Ile Gly Leu  Leu Leu Phe Leu Val  Met Phe Ile 
    1655                 1660                 1665             


Tyr Ala  Ile Phe Gly Met Ser  Asn Phe Ala Tyr Val  Lys Lys Glu 
    1670                 1675                 1680             


Ala Gly  Ile Asp Asp Met Phe  Asn Phe Glu Thr Phe  Gly Asn Ser 
    1685                 1690                 1695             


Met Ile  Cys Leu Phe Gln Ile  Thr Thr Ser Ala Gly  Trp Asp Gly 
    1700                 1705                 1710             


Leu Leu  Ala Pro Ile Leu Asn  Ser Ala Pro Pro Asp  Cys Asp Pro 
    1715                 1720                 1725             


Asp Thr  Ile His Pro Gly Ser  Ser Val Lys Gly Asp  Cys Gly Asn 
    1730                 1735                 1740             


Pro Ser  Val Gly Ile Phe Phe  Phe Val Ser Tyr Ile  Ile Ile Ser 
    1745                 1750                 1755             


Phe Leu  Val Val Val Asn Met  Tyr Ile Ala Val Ile  Leu Glu Asn 
    1760                 1765                 1770             


Phe Ser  Val Ala Thr Glu Glu  Ser Ala Glu Pro Leu  Ser Glu Asp 
    1775                 1780                 1785             


Asp Phe  Glu Met Phe Tyr Glu  Val Trp Glu Lys Phe  Asp Pro Asp 
    1790                 1795                 1800             


Ala Thr  Gln Phe Ile Glu Phe  Ser Lys Leu Ser Asp  Phe Ala Ala 
    1805                 1810                 1815             


Ala Leu  Asp Pro Pro Leu Leu  Ile Ala Lys Pro Asn  Lys Val Gln 
    1820                 1825                 1830             


Leu Ile  Ala Met Asp Leu Pro  Met Val Ser Gly Asp  Arg Ile His 
    1835                 1840                 1845             


Cys Leu  Asp Ile Leu Phe Ala  Phe Thr Lys Arg Val  Leu Gly Glu 
    1850                 1855                 1860             


Ser Gly  Glu Met Asp Ala Leu  Arg Ile Gln Met Glu  Asp Arg Phe 
    1865                 1870                 1875             


Met Ala  Ser Asn Pro Ser Lys  Val Ser Tyr Glu Pro  Ile Thr Thr 
    1880                 1885                 1890             


Thr Leu  Lys Arg Lys Gln Glu  Glu Val Ser Ala Ala  Ile Ile Gln 
    1895                 1900                 1905             


Arg Asn  Phe Arg Cys Tyr Leu  Leu Lys Gln Arg Leu  Lys Asn Ile 
    1910                 1915                 1920             


Ser Ser  Asn Tyr Asn Lys Glu  Ala Ile Lys Gly Arg  Ile Asp Leu 
    1925                 1930                 1935             


Pro Ile  Lys Gln Asp Met Ile  Ile Asp Lys Leu Asn  Gly Asn Ser 
    1940                 1945                 1950             


Thr Pro  Glu Lys Thr Asp Gly  Ser Ser Ser Thr Thr  Ser Pro Pro 
    1955                 1960                 1965             


Ser Tyr  Asp Ser Val Thr Lys  Pro Asp Lys Glu Lys  Phe Glu Lys 
    1970                 1975                 1980             


Asp Lys  Pro Glu Lys Glu Ser  Lys Gly Lys Glu Val  Arg Glu Asn 
    1985                 1990                 1995             


Gln Lys  
    2000 


<210>  3053
<211>  3957
<212>  PRT
<213>  homo sapiens

<400>  3053

Met Met Asn Glu Asp Ala Ala Gln Lys Ser Asp Ser Gly Glu Lys Phe 
1               5                   10                  15      


Asn Gly Ser Ser Gln Arg Arg Lys Arg Pro Lys Lys Ser Asp Ser Asn 
            20                  25                  30          


Ala Ser Phe Leu Arg Ala Ala Arg Ala Gly Asn Leu Asp Lys Val Val 
        35                  40                  45              


Glu Tyr Leu Lys Gly Gly Ile Asp Ile Asn Thr Cys Asn Gln Asn Gly 
    50                  55                  60                  


Leu Asn Ala Leu His Leu Ala Ala Lys Glu Gly His Val Gly Leu Val 
65                  70                  75                  80  


Gln Glu Leu Leu Gly Arg Gly Ser Ser Val Asp Ser Ala Thr Lys Lys 
                85                  90                  95      


Gly Asn Thr Ala Leu His Ile Ala Ser Leu Ala Gly Gln Ala Glu Val 
            100                 105                 110         


Val Lys Val Leu Val Lys Glu Gly Ala Asn Ile Asn Ala Gln Ser Gln 
        115                 120                 125             


Asn Gly Phe Thr Pro Leu Tyr Met Ala Ala Gln Glu Asn His Ile Asp 
    130                 135                 140                 


Val Val Lys Tyr Leu Leu Glu Asn Gly Ala Asn Gln Ser Thr Ala Thr 
145                 150                 155                 160 


Glu Asp Gly Phe Thr Pro Leu Ala Val Ala Leu Gln Gln Gly His Asn 
                165                 170                 175     


Gln Ala Val Ala Ile Leu Leu Glu Asn Asp Thr Lys Gly Lys Val Arg 
            180                 185                 190         


Leu Pro Ala Leu His Ile Ala Ala Arg Lys Asp Asp Thr Lys Ser Ala 
        195                 200                 205             


Ala Leu Leu Leu Gln Asn Asp His Asn Ala Asp Val Gln Ser Lys Met 
    210                 215                 220                 


Met Val Asn Arg Thr Thr Glu Ser Gly Phe Thr Pro Leu His Ile Ala 
225                 230                 235                 240 


Ala His Tyr Gly Asn Val Asn Val Ala Thr Leu Leu Leu Asn Arg Gly 
                245                 250                 255     


Ala Ala Val Asp Phe Thr Ala Arg Asn Gly Ile Thr Pro Leu His Val 
            260                 265                 270         


Ala Ser Lys Arg Gly Asn Thr Asn Met Val Lys Leu Leu Leu Asp Arg 
        275                 280                 285             


Gly Gly Gln Ile Asp Ala Lys Thr Arg Asp Gly Leu Thr Pro Leu His 
    290                 295                 300                 


Cys Ala Ala Arg Ser Gly His Asp Gln Val Val Glu Leu Leu Leu Glu 
305                 310                 315                 320 


Arg Gly Ala Pro Leu Leu Ala Arg Thr Lys Asn Gly Leu Ser Pro Leu 
                325                 330                 335     


His Met Ala Ala Gln Gly Asp His Val Glu Cys Val Lys His Leu Leu 
            340                 345                 350         


Gln His Lys Ala Pro Val Asp Asp Val Thr Leu Asp Tyr Leu Thr Ala 
        355                 360                 365             


Leu His Val Ala Ala His Cys Gly His Tyr Arg Val Thr Lys Leu Leu 
    370                 375                 380                 


Leu Asp Lys Arg Ala Asn Pro Asn Ala Arg Ala Leu Asn Gly Phe Thr 
385                 390                 395                 400 


Pro Leu His Ile Ala Cys Lys Lys Asn Arg Ile Lys Val Met Glu Leu 
                405                 410                 415     


Leu Val Lys Tyr Gly Ala Ser Ile Gln Ala Ile Thr Glu Ser Gly Leu 
            420                 425                 430         


Thr Pro Ile His Val Ala Ala Phe Met Gly His Leu Asn Ile Val Leu 
        435                 440                 445             


Leu Leu Leu Gln Asn Gly Ala Ser Pro Asp Val Thr Asn Ile Arg Gly 
    450                 455                 460                 


Glu Thr Ala Leu His Met Ala Ala Arg Ala Gly Gln Val Glu Val Val 
465                 470                 475                 480 


Arg Cys Leu Leu Arg Asn Gly Ala Leu Val Asp Ala Arg Ala Arg Glu 
                485                 490                 495     


Glu Gln Thr Pro Leu His Ile Ala Ser Arg Leu Gly Lys Thr Glu Ile 
            500                 505                 510         


Val Gln Leu Leu Leu Gln His Met Ala His Pro Asp Ala Ala Thr Thr 
        515                 520                 525             


Asn Gly Tyr Thr Pro Leu His Ile Ser Ala Arg Glu Gly Gln Val Asp 
    530                 535                 540                 


Val Ala Ser Val Leu Leu Glu Ala Gly Ala Ala His Ser Leu Ala Thr 
545                 550                 555                 560 


Lys Lys Gly Phe Thr Pro Leu His Val Ala Ala Lys Tyr Gly Ser Leu 
                565                 570                 575     


Asp Val Ala Lys Leu Leu Leu Gln Arg Arg Ala Ala Ala Asp Ser Ala 
            580                 585                 590         


Gly Lys Asn Gly Leu Thr Pro Leu His Val Ala Ala His Tyr Asp Asn 
        595                 600                 605             


Gln Lys Val Ala Leu Leu Leu Leu Glu Lys Gly Ala Ser Pro His Ala 
    610                 615                 620                 


Thr Ala Lys Asn Gly Tyr Thr Pro Leu His Ile Ala Ala Lys Lys Asn 
625                 630                 635                 640 


Gln Met Gln Ile Ala Ser Thr Leu Leu Asn Tyr Gly Ala Glu Thr Asn 
                645                 650                 655     


Ile Val Thr Lys Gln Gly Val Thr Pro Leu His Leu Ala Ser Gln Glu 
            660                 665                 670         


Gly His Thr Asp Met Val Thr Leu Leu Leu Asp Lys Gly Ala Asn Ile 
        675                 680                 685             


His Met Ser Thr Lys Ser Gly Leu Thr Ser Leu His Leu Ala Ala Gln 
    690                 695                 700                 


Glu Asp Lys Val Asn Val Ala Asp Ile Leu Thr Lys His Gly Ala Asp 
705                 710                 715                 720 


Gln Asp Ala His Thr Lys Leu Gly Tyr Thr Pro Leu Ile Val Ala Cys 
                725                 730                 735     


His Tyr Gly Asn Val Lys Met Val Asn Phe Leu Leu Lys Gln Gly Ala 
            740                 745                 750         


Asn Val Asn Ala Lys Thr Lys Asn Gly Tyr Thr Pro Leu His Gln Ala 
        755                 760                 765             


Ala Gln Gln Gly His Thr His Ile Ile Asn Val Leu Leu Gln His Gly 
    770                 775                 780                 


Ala Lys Pro Asn Ala Thr Thr Ala Asn Gly Asn Thr Ala Leu Ala Ile 
785                 790                 795                 800 


Ala Lys Arg Leu Gly Tyr Ile Ser Val Val Asp Thr Leu Lys Val Val 
                805                 810                 815     


Thr Glu Glu Val Thr Thr Thr Thr Thr Thr Ile Thr Glu Lys His Lys 
            820                 825                 830         


Leu Asn Val Pro Glu Thr Met Thr Glu Val Leu Asp Val Ser Asp Glu 
        835                 840                 845             


Glu Gly Asp Asp Thr Met Thr Gly Asp Gly Gly Glu Tyr Leu Arg Pro 
    850                 855                 860                 


Glu Asp Leu Lys Glu Leu Gly Asp Asp Ser Leu Pro Ser Ser Gln Phe 
865                 870                 875                 880 


Leu Asp Gly Met Asn Tyr Leu Arg Tyr Ser Leu Glu Gly Gly Arg Ser 
                885                 890                 895     


Asp Ser Leu Arg Ser Phe Ser Ser Asp Arg Ser His Thr Leu Ser His 
            900                 905                 910         


Ala Ser Tyr Leu Arg Asp Ser Ala Val Met Asp Asp Ser Val Val Ile 
        915                 920                 925             


Pro Ser His Gln Val Ser Thr Leu Ala Lys Glu Ala Glu Arg Asn Ser 
    930                 935                 940                 


Tyr Arg Leu Ser Trp Gly Thr Glu Asn Leu Asp Asn Val Ala Leu Ser 
945                 950                 955                 960 


Ser Ser Pro Ile His Ser Gly Phe Leu Val Ser Phe Met Val Asp Ala 
                965                 970                 975     


Arg Gly Gly Ala Met Arg Gly Cys Arg His Asn Gly Leu Arg Ile Ile 
            980                 985                 990         


Ile Pro Pro Arg Lys Cys Thr Ala  Pro Thr Arg Val Thr  Cys Arg Leu 
        995                 1000                 1005             


Val Lys  Arg His Arg Leu Ala  Thr Met Pro Pro Met  Val Glu Gly 
    1010                 1015                 1020             


Glu Gly  Leu Ala Ser Arg Leu  Ile Glu Val Gly Pro  Ser Gly Ala 
    1025                 1030                 1035             


Gln Phe  Leu Gly Lys Leu His  Leu Pro Thr Ala Pro  Pro Pro Leu 
    1040                 1045                 1050             


Asn Glu  Gly Glu Ser Leu Val  Ser Arg Ile Leu Gln  Leu Gly Pro 
    1055                 1060                 1065             


Pro Gly  Thr Lys Phe Leu Gly  Pro Val Ile Val Glu  Ile Pro His 
    1070                 1075                 1080             


Phe Ala  Ala Leu Arg Gly Lys  Glu Arg Glu Leu Val  Val Leu Arg 
    1085                 1090                 1095             


Ser Glu  Asn Gly Asp Ser Trp  Lys Glu His Phe Cys  Asp Tyr Thr 
    1100                 1105                 1110             


Glu Asp  Glu Leu Asn Glu Ile  Leu Asn Gly Met Asp  Glu Val Leu 
    1115                 1120                 1125             


Asp Ser  Pro Glu Asp Leu Glu  Lys Lys Arg Ile Cys  Arg Ile Ile 
    1130                 1135                 1140             


Thr Arg  Asp Phe Pro Gln Tyr  Phe Ala Val Val Ser  Arg Ile Lys 
    1145                 1150                 1155             


Gln Asp  Ser Asn Leu Ile Gly  Pro Glu Gly Gly Val  Leu Ser Ser 
    1160                 1165                 1170             


Thr Val  Val Pro Gln Val Gln  Ala Val Phe Pro Glu  Gly Ala Leu 
    1175                 1180                 1185             


Thr Lys  Arg Ile Arg Val Gly  Leu Gln Ala Gln Pro  Met His Ser 
    1190                 1195                 1200             


Glu Leu  Val Lys Lys Ile Leu  Gly Asn Lys Ala Thr  Phe Ser Pro 
    1205                 1210                 1215             


Ile Val  Thr Leu Glu Pro Arg  Arg Arg Lys Phe His  Lys Pro Ile 
    1220                 1225                 1230             


Thr Met  Thr Ile Pro Val Pro  Lys Ala Ser Ser Asp  Val Met Leu 
    1235                 1240                 1245             


Asn Gly  Phe Gly Gly Asp Ala  Pro Thr Leu Arg Leu  Leu Cys Ser 
    1250                 1255                 1260             


Ile Thr  Gly Gly Thr Thr Pro  Ala Gln Trp Glu Asp  Ile Thr Gly 
    1265                 1270                 1275             


Thr Thr  Pro Leu Thr Phe Val  Asn Glu Cys Val Ser  Phe Thr Thr 
    1280                 1285                 1290             


Asn Val  Ser Ala Arg Phe Trp  Leu Ile Asp Cys Arg  Gln Ile Gln 
    1295                 1300                 1305             


Glu Ser  Val Thr Phe Ala Ser  Gln Val Tyr Arg Glu  Ile Ile Cys 
    1310                 1315                 1320             


Val Pro  Tyr Met Ala Lys Phe  Val Val Phe Ala Lys  Ser His Asp 
    1325                 1330                 1335             


Pro Ile  Glu Ala Arg Leu Arg  Cys Phe Cys Met Thr  Asp Asp Lys 
    1340                 1345                 1350             


Val Asp  Lys Thr Leu Glu Gln  Gln Glu Asn Phe Ala  Glu Val Ala 
    1355                 1360                 1365             


Arg Ser  Arg Asp Val Glu Val  Leu Glu Gly Lys Pro  Ile Tyr Val 
    1370                 1375                 1380             


Asp Cys  Phe Gly Asn Leu Val  Pro Leu Thr Lys Ser  Gly Gln His 
    1385                 1390                 1395             


His Ile  Phe Ser Phe Phe Ala  Phe Lys Glu Asn Arg  Leu Pro Leu 
    1400                 1405                 1410             


Phe Val  Lys Val Arg Asp Thr  Thr Gln Glu Pro Cys  Gly Arg Leu 
    1415                 1420                 1425             


Ser Phe  Met Lys Glu Pro Lys  Ser Thr Arg Gly Leu  Val His Gln 
    1430                 1435                 1440             


Ala Ile  Cys Asn Leu Asn Ile  Thr Leu Pro Ile Tyr  Thr Lys Glu 
    1445                 1450                 1455             


Ser Glu  Ser Asp Gln Glu Gln  Glu Glu Glu Ile Asp  Met Thr Ser 
    1460                 1465                 1470             


Glu Lys  Asn Asp Glu Thr Glu  Ser Thr Glu Thr Ser  Val Leu Lys 
    1475                 1480                 1485             


Ser His  Leu Val Asn Glu Val  Pro Val Leu Ala Ser  Pro Asp Leu 
    1490                 1495                 1500             


Leu Ser  Glu Val Ser Glu Met  Lys Gln Asp Leu Ile  Lys Met Thr 
    1505                 1510                 1515             


Ala Ile  Leu Thr Thr Asp Val  Ser Asp Lys Ala Gly  Ser Ile Lys 
    1520                 1525                 1530             


Val Lys  Glu Leu Val Lys Ala  Ala Glu Glu Glu Pro  Gly Glu Pro 
    1535                 1540                 1545             


Phe Glu  Ile Val Glu Arg Val  Lys Glu Asp Leu Glu  Lys Val Asn 
    1550                 1555                 1560             


Glu Ile  Leu Arg Ser Gly Thr  Cys Thr Arg Asp Glu  Ser Ser Val 
    1565                 1570                 1575             


Gln Ser  Ser Arg Ser Glu Arg  Gly Leu Val Glu Glu  Glu Trp Val 
    1580                 1585                 1590             


Ile Val  Ser Asp Glu Glu Ile  Glu Glu Ala Arg Gln  Lys Ala Pro 
    1595                 1600                 1605             


Leu Glu  Ile Thr Glu Tyr Pro  Cys Val Glu Val Arg  Ile Asp Lys 
    1610                 1615                 1620             


Glu Ile  Lys Gly Lys Val Glu  Lys Asp Ser Thr Gly  Leu Val Asn 
    1625                 1630                 1635             


Tyr Leu  Thr Asp Asp Leu Asn  Thr Cys Val Pro Leu  Pro Lys Glu 
    1640                 1645                 1650             


Gln Leu  Gln Thr Val Gln Asp  Lys Ala Gly Lys Lys  Cys Glu Ala 
    1655                 1660                 1665             


Leu Ala  Val Gly Arg Ser Ser  Glu Lys Glu Gly Lys  Asp Ile Pro 
    1670                 1675                 1680             


Pro Asp  Glu Thr Gln Ser Thr  Gln Lys Gln His Lys  Pro Ser Leu 
    1685                 1690                 1695             


Gly Ile  Lys Lys Pro Val Arg  Arg Lys Leu Lys Glu  Lys Gln Lys 
    1700                 1705                 1710             


Gln Lys  Glu Glu Gly Leu Gln  Ala Ser Ala Glu Lys  Ala Glu Leu 
    1715                 1720                 1725             


Lys Lys  Gly Ser Ser Glu Glu  Ser Leu Gly Glu Asp  Pro Gly Leu 
    1730                 1735                 1740             


Ala Pro  Glu Pro Leu Pro Thr  Val Lys Ala Thr Ser  Pro Leu Ile 
    1745                 1750                 1755             


Glu Glu  Thr Pro Ile Gly Ser  Ile Lys Asp Lys Val  Lys Ala Leu 
    1760                 1765                 1770             


Gln Lys  Arg Val Glu Asp Glu  Gln Lys Gly Arg Ser  Lys Leu Pro 
    1775                 1780                 1785             


Ile Arg  Val Lys Gly Lys Glu  Asp Val Pro Lys Lys  Thr Thr His 
    1790                 1795                 1800             


Arg Pro  His Pro Ala Ala Ser  Pro Ser Leu Lys Ser  Glu Arg His 
    1805                 1810                 1815             


Ala Pro  Gly Ser Pro Ser Pro  Lys Thr Glu Arg His  Ser Thr Leu 
    1820                 1825                 1830             


Ser Ser  Ser Ala Lys Thr Glu  Arg His Pro Pro Val  Ser Pro Ser 
    1835                 1840                 1845             


Ser Lys  Thr Glu Lys His Ser  Pro Val Ser Pro Ser  Ala Lys Thr 
    1850                 1855                 1860             


Glu Arg  His Ser Pro Ala Ser  Ser Ser Ser Lys Thr  Glu Lys His 
    1865                 1870                 1875             


Ser Pro  Val Ser Pro Ser Thr  Lys Thr Glu Arg His  Ser Pro Val 
    1880                 1885                 1890             


Ser Ser  Thr Lys Thr Glu Arg  His Pro Pro Val Ser  Pro Ser Gly 
    1895                 1900                 1905             


Lys Thr  Asp Lys Arg Pro Pro  Val Ser Pro Ser Gly  Arg Thr Glu 
    1910                 1915                 1920             


Lys His  Pro Pro Val Ser Pro  Gly Arg Thr Glu Lys  Arg Leu Pro 
    1925                 1930                 1935             


Val Ser  Pro Ser Gly Arg Thr  Asp Lys His Gln Pro  Val Ser Thr 
    1940                 1945                 1950             


Ala Gly  Lys Thr Glu Lys His  Leu Pro Val Ser Pro  Ser Gly Lys 
    1955                 1960                 1965             


Thr Glu  Lys Gln Pro Pro Val  Ser Pro Thr Ser Lys  Thr Glu Arg 
    1970                 1975                 1980             


Ile Glu  Glu Thr Met Ser Val  Arg Glu Leu Met Lys  Ala Phe Gln 
    1985                 1990                 1995             


Ser Gly  Gln Asp Pro Ser Lys  His Lys Thr Gly Leu  Phe Glu His 
    2000                 2005                 2010             


Lys Ser  Ala Lys Gln Lys Gln  Pro Gln Glu Lys Gly  Lys Val Arg 
    2015                 2020                 2025             


Val Glu  Lys Glu Lys Gly Pro  Ile Leu Thr Gln Arg  Glu Ala Gln 
    2030                 2035                 2040             


Lys Thr  Glu Asn Gln Thr Ile  Lys Arg Gly Gln Arg  Leu Pro Val 
    2045                 2050                 2055             


Thr Gly  Thr Ala Glu Ser Lys  Arg Gly Val Arg Val  Ser Ser Ile 
    2060                 2065                 2070             


Gly Val  Lys Lys Glu Asp Ala  Ala Gly Gly Lys Glu  Lys Val Leu 
    2075                 2080                 2085             


Ser His  Lys Ile Pro Glu Pro  Val Gln Ser Val Pro  Glu Glu Glu 
    2090                 2095                 2100             


Ser His  Arg Glu Ser Glu Val  Pro Lys Glu Lys Met  Ala Asp Glu 
    2105                 2110                 2115             


Gln Gly  Asp Met Asp Leu Gln  Ile Ser Pro Asp Arg  Lys Thr Ser 
    2120                 2125                 2130             


Thr Asp  Phe Ser Glu Val Ile  Lys Gln Glu Leu Glu  Asp Asn Asp 
    2135                 2140                 2145             


Lys Tyr  Gln Gln Phe Arg Leu  Ser Glu Glu Thr Glu  Lys Ala Gln 
    2150                 2155                 2160             


Leu His  Leu Asp Gln Val Leu  Thr Ser Pro Phe Asn  Thr Thr Phe 
    2165                 2170                 2175             


Pro Leu  Asp Tyr Met Lys Asp  Glu Phe Leu Pro Ala  Leu Ser Leu 
    2180                 2185                 2190             


Gln Ser  Gly Ala Leu Asp Gly  Ser Ser Glu Ser Leu  Lys Asn Glu 
    2195                 2200                 2205             


Gly Val  Ala Gly Ser Pro Cys  Gly Ser Leu Met Glu  Gly Thr Pro 
    2210                 2215                 2220             


Gln Ile  Ser Ser Glu Glu Ser  Tyr Lys His Glu Gly  Leu Ala Glu 
    2225                 2230                 2235             


Thr Pro  Glu Thr Ser Pro Glu  Ser Leu Ser Phe Ser  Pro Lys Lys 
    2240                 2245                 2250             


Ser Glu  Glu Gln Thr Gly Glu  Thr Lys Glu Ser Thr  Lys Thr Glu 
    2255                 2260                 2265             


Thr Thr  Thr Glu Ile Arg Ser  Glu Lys Glu His Pro  Thr Thr Lys 
    2270                 2275                 2280             


Asp Ile  Thr Gly Gly Ser Glu  Glu Arg Gly Ala Thr  Val Thr Glu 
    2285                 2290                 2295             


Asp Ser  Glu Thr Ser Thr Glu  Ser Phe Gln Lys Glu  Ala Thr Leu 
    2300                 2305                 2310             


Gly Ser  Pro Lys Asp Thr Ser  Pro Lys Arg Gln Asp  Asp Cys Thr 
    2315                 2320                 2325             


Gly Ser  Cys Ser Val Ala Leu  Ala Lys Glu Thr Pro  Thr Gly Leu 
    2330                 2335                 2340             


Thr Glu  Glu Ala Ala Cys Asp  Glu Gly Gln Arg Thr  Phe Gly Ser 
    2345                 2350                 2355             


Ser Ala  His Lys Thr Gln Thr  Asp Ser Glu Val Gln  Glu Ser Thr 
    2360                 2365                 2370             


Ala Thr  Ser Asp Glu Thr Lys  Ala Leu Pro Leu Pro  Glu Ala Ser 
    2375                 2380                 2385             


Val Lys  Thr Asp Thr Gly Thr  Glu Ser Lys Pro Gln  Gly Val Ile 
    2390                 2395                 2400             


Arg Ser  Pro Gln Gly Leu Glu  Leu Ala Leu Pro Ser  Arg Asp Ser 
    2405                 2410                 2415             


Glu Val  Leu Ser Ala Val Ala  Asp Asp Ser Leu Ala  Val Ser His 
    2420                 2425                 2430             


Lys Asp  Ser Leu Glu Ala Ser  Pro Val Leu Glu Asp  Asn Ser Ser 
    2435                 2440                 2445             


His Lys  Thr Pro Asp Ser Leu  Glu Pro Ser Pro Leu  Lys Glu Ser 
    2450                 2455                 2460             


Pro Cys  Arg Asp Ser Leu Glu  Ser Ser Pro Val Glu  Pro Lys Met 
    2465                 2470                 2475             


Lys Ala  Gly Ile Phe Pro Ser  His Phe Pro Leu Pro  Ala Ala Val 
    2480                 2485                 2490             


Ala Lys  Thr Glu Leu Leu Thr  Glu Val Ala Ser Val  Arg Ser Arg 
    2495                 2500                 2505             


Leu Leu  Arg Asp Pro Asp Gly  Ser Ala Glu Asp Asp  Ser Leu Glu 
    2510                 2515                 2520             


Gln Thr  Ser Leu Met Glu Ser  Ser Gly Lys Ser Pro  Leu Ser Pro 
    2525                 2530                 2535             


Asp Thr  Pro Ser Ser Glu Glu  Val Ser Tyr Glu Val  Thr Pro Lys 
    2540                 2545                 2550             


Thr Thr  Asp Val Ser Thr Pro  Lys Pro Ala Val Ile  His Glu Cys 
    2555                 2560                 2565             


Ala Glu  Glu Asp Asp Ser Glu  Asn Gly Glu Lys Lys  Arg Phe Thr 
    2570                 2575                 2580             


Pro Glu  Glu Glu Met Phe Lys  Met Val Thr Lys Ile  Lys Met Phe 
    2585                 2590                 2595             


Asp Glu  Leu Glu Gln Glu Ala  Lys Gln Lys Arg Asp  Tyr Lys Lys 
    2600                 2605                 2610             


Glu Pro  Lys Gln Glu Glu Ser  Ser Ser Ser Ser Asp  Pro Asp Ala 
    2615                 2620                 2625             


Asp Cys  Ser Val Asp Val Asp  Glu Pro Lys His Thr  Gly Ser Gly 
    2630                 2635                 2640             


Glu Asp  Glu Ser Gly Val Pro  Val Leu Val Thr Ser  Glu Ser Arg 
    2645                 2650                 2655             


Lys Val  Ser Ser Ser Ser Glu  Ser Glu Pro Glu Leu  Ala Gln Leu 
    2660                 2665                 2670             


Lys Lys  Gly Ala Asp Ser Gly  Leu Leu Pro Glu Pro  Val Ile Arg 
    2675                 2680                 2685             


Val Gln  Pro Pro Ser Pro Leu  Pro Ser Ser Met Asp  Ser Asn Ser 
    2690                 2695                 2700             


Ser Pro  Glu Glu Val Gln Phe  Gln Pro Val Val Ser  Lys Gln Tyr 
    2705                 2710                 2715             


Thr Phe  Lys Met Asn Glu Asp  Thr Gln Glu Glu Pro  Gly Lys Ser 
    2720                 2725                 2730             


Glu Glu  Glu Lys Asp Ser Glu  Ser His Leu Ala Glu  Asp Arg His 
    2735                 2740                 2745             


Ala Val  Ser Thr Glu Ala Glu  Asp Arg Ser Tyr Asp  Lys Leu Asn 
    2750                 2755                 2760             


Arg Asp  Thr Asp Gln Pro Lys  Ile Cys Asp Gly His  Gly Cys Glu 
    2765                 2770                 2775             


Ala Met  Ser Pro Ser Ser Ser  Ala Ala Pro Val Ser  Ser Gly Leu 
    2780                 2785                 2790             


Gln Ser  Pro Thr Gly Asp Asp  Val Asp Glu Gln Pro  Val Ile Tyr 
    2795                 2800                 2805             


Lys Glu  Ser Leu Ala Leu Gln  Gly Thr His Glu Lys  Asp Thr Glu 
    2810                 2815                 2820             


Gly Glu  Glu Leu Asp Val Ser  Arg Ala Glu Ser Pro  Gln Ala Asp 
    2825                 2830                 2835             


Cys Pro  Ser Glu Ser Phe Ser  Ser Ser Ser Ser Leu  Pro His Cys 
    2840                 2845                 2850             


Leu Val  Ser Glu Gly Lys Glu  Leu Asp Glu Asp Ile  Ser Ala Thr 
    2855                 2860                 2865             


Ser Ser  Ile Gln Lys Thr Glu  Val Thr Lys Thr Asp  Glu Thr Phe 
    2870                 2875                 2880             


Glu Asn  Leu Pro Lys Asp Cys  Pro Ser Gln Asp Ser  Ser Ile Thr 
    2885                 2890                 2895             


Thr Gln  Thr Asp Arg Phe Ser  Met Asp Val Pro Val  Ser Asp Leu 
    2900                 2905                 2910             


Ala Glu  Asn Asp Glu Ile Tyr  Asp Pro Gln Ile Thr  Ser Pro Tyr 
    2915                 2920                 2925             


Glu Asn  Val Pro Ser Gln Ser  Phe Phe Ser Ser Glu  Glu Ser Lys 
    2930                 2935                 2940             


Thr Gln  Thr Asp Ala Asn His  Thr Thr Ser Phe His  Ser Ser Glu 
    2945                 2950                 2955             


Val Tyr  Ser Val Thr Ile Thr  Ser Pro Val Glu Asp  Val Val Val 
    2960                 2965                 2970             


Ala Ser  Ser Ser Ser Gly Thr  Val Leu Ser Lys Glu  Ser Asn Phe 
    2975                 2980                 2985             


Glu Gly  Gln Asp Ile Lys Met  Glu Ser Gln Gln Glu  Ser Thr Leu 
    2990                 2995                 3000             


Trp Glu  Met Gln Ser Asp Ser  Val Ser Ser Ser Phe  Glu Pro Thr 
    3005                 3010                 3015             


Met Ser  Ala Thr Thr Thr Val  Val Gly Glu Gln Ile  Ser Lys Val 
    3020                 3025                 3030             


Ile Ile  Thr Lys Thr Asp Val  Asp Ser Asp Ser Trp  Ser Glu Ile 
    3035                 3040                 3045             


Arg Glu  Asp Asp Glu Ala Phe  Glu Ala Arg Val Lys  Glu Glu Glu 
    3050                 3055                 3060             


Gln Lys  Ile Phe Gly Leu Met  Val Asp Arg Gln Ser  Gln Gly Thr 
    3065                 3070                 3075             


Thr Pro  Asp Thr Thr Pro Ala  Arg Thr Pro Thr Glu  Glu Gly Thr 
    3080                 3085                 3090             


Pro Thr  Ser Glu Gln Asn Pro  Phe Leu Phe Gln Glu  Gly Lys Leu 
    3095                 3100                 3105             


Phe Glu  Met Thr Arg Ser Gly  Ala Ile Asp Met Thr  Lys Arg Ser 
    3110                 3115                 3120             


Tyr Ala  Asp Glu Ser Phe His  Phe Phe Gln Ile Gly  Gln Glu Ser 
    3125                 3130                 3135             


Arg Glu  Glu Thr Leu Ser Glu  Asp Val Lys Glu Gly  Ala Thr Gly 
    3140                 3145                 3150             


Ala Asp  Pro Leu Pro Leu Glu  Thr Ser Ala Glu Ser  Leu Ala Leu 
    3155                 3160                 3165             


Ser Glu  Ser Lys Glu Thr Val  Asp Asp Glu Ala Asp  Leu Leu Pro 
    3170                 3175                 3180             


Asp Asp  Val Ser Glu Glu Val  Glu Glu Ile Pro Ala  Ser Asp Ala 
    3185                 3190                 3195             


Gln Leu  Asn Ser Gln Met Gly  Ile Ser Ala Ser Thr  Glu Thr Pro 
    3200                 3205                 3210             


Thr Lys  Glu Ala Val Ser Val  Gly Thr Lys Asp Leu  Pro Thr Val 
    3215                 3220                 3225             


Gln Thr  Gly Asp Ile Pro Pro  Leu Ser Gly Val Lys  Gln Ile Ser 
    3230                 3235                 3240             


Cys Pro  Asp Ser Ser Glu Pro  Ala Val Gln Val Gln  Leu Asp Phe 
    3245                 3250                 3255             


Ser Thr  Leu Thr Arg Ser Val  Tyr Ser Asp Arg Gly  Asp Asp Ser 
    3260                 3265                 3270             


Pro Asp  Ser Ser Pro Glu Glu  Gln Lys Ser Val Ile  Glu Ile Pro 
    3275                 3280                 3285             


Thr Ala  Pro Met Glu Asn Val  Pro Phe Thr Glu Ser  Lys Ser Lys 
    3290                 3295                 3300             


Ile Pro  Val Arg Thr Met Pro  Thr Ser Thr Pro Ala  Pro Pro Ser 
    3305                 3310                 3315             


Ala Glu  Tyr Glu Ser Ser Val  Ser Glu Asp Phe Leu  Ser Ser Val 
    3320                 3325                 3330             


Asp Glu  Glu Asn Lys Ala Asp  Glu Ala Lys Pro Lys  Ser Lys Leu 
    3335                 3340                 3345             


Pro Val  Lys Val Pro Leu Gln  Arg Val Glu Gln Gln  Leu Ser Asp 
    3350                 3355                 3360             


Leu Asp  Thr Ser Val Gln Lys  Thr Val Ala Pro Gln  Gly Gln Asp 
    3365                 3370                 3375             


Met Ala  Ser Ile Ala Pro Asp  Asn Arg Ser Lys Ser  Glu Ser Asp 
    3380                 3385                 3390             


Ala Ser  Ser Leu Asp Ser Lys  Thr Lys Cys Pro Val  Lys Thr Arg 
    3395                 3400                 3405             


Ser Tyr  Thr Glu Thr Glu Thr  Glu Ser Arg Glu Arg  Ala Glu Glu 
    3410                 3415                 3420             


Leu Glu  Leu Glu Ser Glu Glu  Gly Ala Thr Arg Pro  Lys Ile Leu 
    3425                 3430                 3435             


Thr Ser  Arg Leu Pro Val Lys  Ser Arg Ser Thr Thr  Ser Ser Cys 
    3440                 3445                 3450             


Arg Gly  Gly Thr Ser Pro Thr  Lys Glu Ser Lys Glu  His Phe Phe 
    3455                 3460                 3465             


Asp Leu  Tyr Arg Asn Ser Ile  Glu Phe Phe Glu Glu  Ile Ser Asp 
    3470                 3475                 3480             


Glu Ala  Ser Lys Leu Val Asp  Arg Leu Thr Gln Ser  Glu Arg Glu 
    3485                 3490                 3495             


Gln Glu  Ile Val Ser Asp Asp  Glu Ser Ser Ser Ala  Leu Glu Val 
    3500                 3505                 3510             


Ser Val  Ile Glu Asn Leu Pro  Pro Val Glu Thr Glu  His Ser Val 
    3515                 3520                 3525             


Pro Glu  Asp Ile Phe Asp Thr  Arg Pro Ile Trp Asp  Glu Ser Ile 
    3530                 3535                 3540             


Glu Thr  Leu Ile Glu Arg Ile  Pro Asp Glu Asn Gly  His Asp His 
    3545                 3550                 3555             


Ala Glu  Asp Pro Gln Asp Glu  Gln Glu Arg Ile Glu  Glu Arg Leu 
    3560                 3565                 3570             


Ala Tyr  Ile Ala Asp His Leu  Gly Phe Ser Trp Thr  Glu Leu Ala 
    3575                 3580                 3585             


Arg Glu  Leu Asp Phe Thr Glu  Glu Gln Ile His Gln  Ile Arg Ile 
    3590                 3595                 3600             


Glu Asn  Pro Asn Ser Leu Gln  Asp Gln Ser His Ala  Leu Leu Lys 
    3605                 3610                 3615             


Tyr Trp  Leu Glu Arg Asp Gly  Lys His Ala Thr Asp  Thr Asn Leu 
    3620                 3625                 3630             


Val Glu  Cys Leu Thr Lys Ile  Asn Arg Met Asp Ile  Val His Leu 
    3635                 3640                 3645             


Met Glu  Thr Asn Thr Glu Pro  Leu Gln Glu Arg Ile  Ser His Ser 
    3650                 3655                 3660             


Tyr Ala  Glu Ile Glu Gln Thr  Ile Thr Leu Asp His  Ser Glu Gly 
    3665                 3670                 3675             


Phe Ser  Val Leu Gln Glu Glu  Leu Cys Thr Ala Gln  His Lys Gln 
    3680                 3685                 3690             


Lys Glu  Glu Gln Ala Val Ser  Lys Glu Ser Glu Thr  Cys Asp His 
    3695                 3700                 3705             


Pro Pro  Ile Val Ser Glu Glu  Asp Ile Ser Val Gly  Tyr Ser Thr 
    3710                 3715                 3720             


Phe Gln  Asp Gly Val Pro Lys  Thr Glu Gly Asp Ser  Ser Ala Thr 
    3725                 3730                 3735             


Ala Leu  Phe Pro Gln Thr His  Lys Glu Gln Val Gln  Gln Asp Phe 
    3740                 3745                 3750             


Ser Gly  Lys Met Gln Asp Leu  Pro Glu Glu Ser Ser  Leu Glu Tyr 
    3755                 3760                 3765             


Gln Gln  Glu Tyr Phe Val Thr  Thr Pro Gly Thr Glu  Thr Ser Glu 
    3770                 3775                 3780             


Thr Gln  Lys Ala Met Ile Val  Pro Ser Ser Pro Ser  Lys Thr Pro 
    3785                 3790                 3795             


Glu Glu  Val Ser Thr Pro Ala  Glu Glu Glu Lys Leu  Tyr Leu Gln 
    3800                 3805                 3810             


Thr Pro  Thr Ser Ser Glu Arg  Gly Gly Ser Pro Ile  Ile Gln Glu 
    3815                 3820                 3825             


Pro Glu  Glu Pro Ser Glu His  Arg Glu Glu Ser Ser  Pro Arg Lys 
    3830                 3835                 3840             


Thr Ser  Leu Val Ile Val Glu  Ser Ala Asp Asn Gln  Pro Glu Thr 
    3845                 3850                 3855             


Cys Glu  Arg Leu Asp Glu Asp  Ala Ala Phe Glu Lys  Gly Asp Asp 
    3860                 3865                 3870             


Met Pro  Glu Ile Pro Pro Glu  Thr Val Thr Glu Glu  Glu Tyr Ile 
    3875                 3880                 3885             


Asp Glu  His Gly His Thr Val  Val Lys Lys Val Thr  Arg Lys Ile 
    3890                 3895                 3900             


Ile Arg  Arg Tyr Val Ser Ser  Glu Gly Thr Glu Lys  Glu Glu Ile 
    3905                 3910                 3915             


Met Val  Gln Gly Met Pro Gln  Glu Pro Val Asn Ile  Glu Glu Gly 
    3920                 3925                 3930             


Asp Gly  Tyr Ser Lys Val Ile  Lys Arg Val Val Leu  Lys Ser Asp 
    3935                 3940                 3945             


Thr Glu  Gln Ser Glu Asp Asn  Asn Glu 
    3950                 3955         


<210>  3054
<211>  504
<212>  PRT
<213>  homo sapiens

<400>  3054

Met Ala Val Pro Ala Ala Leu Ile Pro Pro Thr Gln Leu Val Pro Pro 
1               5                   10                  15      


Gln Pro Pro Ile Ser Thr Ser Ala Ser Ser Ser Gly Thr Thr Thr Ser 
            20                  25                  30          


Thr Ser Ser Ala Thr Ser Ser Pro Ala Pro Ser Ile Gly Pro Pro Ala 
        35                  40                  45              


Ser Ser Gly Pro Thr Leu Phe Arg Pro Glu Pro Ile Ala Ser Ala Ala 
    50                  55                  60                  


Ala Ala Ala Ala Thr Val Thr Ser Thr Gly Gly Gly Gly Gly Gly Gly 
65                  70                  75                  80  


Gly Ser Gly Gly Gly Gly Gly Ser Ser Gly Asn Gly Gly Gly Gly Gly 
                85                  90                  95      


Gly Gly Gly Gly Gly Ser Asn Cys Asn Pro Asn Leu Ala Ala Ala Ser 
            100                 105                 110         


Asn Gly Ser Gly Gly Gly Gly Gly Gly Ile Ser Ala Gly Gly Gly Val 
        115                 120                 125             


Ala Ser Ser Thr Pro Ile Asn Ala Ser Thr Gly Ser Ser Ser Ser Ser 
    130                 135                 140                 


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser 
145                 150                 155                 160 


Ser Ser Ser Cys Gly Pro Leu Pro Gly Lys Pro Val Tyr Ser Thr Pro 
                165                 170                 175     


Ser Pro Val Glu Asn Thr Pro Gln Asn Asn Glu Cys Lys Met Val Asp 
            180                 185                 190         


Leu Arg Gly Ala Lys Val Ala Ser Phe Thr Val Glu Gly Cys Glu Leu 
        195                 200                 205             


Ile Cys Leu Pro Gln Ala Phe Asp Leu Phe Leu Lys His Leu Val Gly 
    210                 215                 220                 


Gly Leu His Thr Val Tyr Thr Lys Leu Lys Arg Leu Glu Ile Thr Pro 
225                 230                 235                 240 


Val Val Cys Asn Val Glu Gln Val Arg Ile Leu Arg Gly Leu Gly Ala 
                245                 250                 255     


Ile Gln Pro Gly Val Asn Arg Cys Lys Leu Ile Ser Arg Lys Asp Phe 
            260                 265                 270         


Glu Thr Leu Tyr Asn Asp Cys Thr Asn Ala Ser Ser Arg Pro Gly Arg 
        275                 280                 285             


Pro Pro Lys Arg Thr Gln Ser Val Thr Ser Pro Glu Asn Ser His Ile 
    290                 295                 300                 


Met Pro His Ser Val Pro Gly Leu Met Ser Pro Gly Ile Ile Pro Pro 
305                 310                 315                 320 


Thr Asp Glu Thr Pro Leu Ser Thr Pro Thr Ala Arg Asp Ser Leu Asp 
                325                 330                 335     


Lys Leu Ser Leu Thr Gly His Gly Gln Pro Leu Pro Pro Gly Phe Pro 
            340                 345                 350         


Ser Pro Phe Leu Phe Pro Asp Gly Leu Ser Ser Ile Glu Thr Leu Leu 
        355                 360                 365             


Thr Asn Ile Gln Gly Leu Leu Lys Val Ala Ile Asp Asn Ala Arg Ala 
    370                 375                 380                 


Gln Glu Lys Gln Val Gln Leu Glu Lys Thr Glu Leu Lys Met Asp Phe 
385                 390                 395                 400 


Leu Arg Glu Arg Glu Leu Arg Glu Thr Leu Glu Lys Gln Leu Ala Met 
                405                 410                 415     


Glu Gln Lys Asn Arg Ala Ile Val Gln Lys Arg Leu Lys Lys Glu Lys 
            420                 425                 430         


Lys Ala Lys Arg Lys Leu Gln Glu Ala Leu Glu Phe Glu Thr Lys Arg 
        435                 440                 445             


Arg Glu Gln Ala Glu Gln Thr Leu Lys Gln Ala Ala Ser Thr Asp Ser 
    450                 455                 460                 


Leu Arg Val Leu Asn Asp Ser Leu Thr Pro Glu Ile Glu Ala Asp Arg 
465                 470                 475                 480 


Ser Gly Gly Arg Thr Asp Ala Glu Arg Thr Ile Gln Asp Gly Arg Leu 
                485                 490                 495     


Tyr Leu Lys Thr Thr Val Met Tyr 
            500                 


<210>  3055
<211>  406
<212>  PRT
<213>  homo sapiens

<400>  3055

Met Ile His Thr Asn Leu Lys Lys Lys Phe Ser Cys Cys Val Leu Val 
1               5                   10                  15      


Phe Leu Leu Phe Ala Val Ile Cys Val Trp Lys Glu Lys Lys Lys Gly 
            20                  25                  30          


Ser Tyr Tyr Asp Ser Phe Lys Leu Gln Thr Lys Glu Phe Gln Val Leu 
        35                  40                  45              


Lys Ser Leu Gly Lys Leu Ala Met Gly Ser Asp Ser Gln Ser Val Ser 
    50                  55                  60                  


Ser Ser Ser Thr Gln Asp Pro His Arg Gly Arg Gln Thr Leu Gly Ser 
65                  70                  75                  80  


Leu Arg Gly Leu Ala Lys Ala Lys Pro Glu Ala Ser Phe Gln Val Trp 
                85                  90                  95      


Asn Lys Asp Ser Ser Ser Lys Asn Leu Ile Pro Arg Leu Gln Lys Ile 
            100                 105                 110         


Trp Lys Asn Tyr Leu Ser Met Asn Lys Tyr Lys Val Ser Tyr Lys Gly 
        115                 120                 125             


Pro Gly Pro Gly Ile Lys Phe Ser Ala Glu Ala Leu Arg Cys His Leu 
    130                 135                 140                 


Arg Asp His Val Asn Val Ser Met Val Glu Val Thr Asp Phe Pro Phe 
145                 150                 155                 160 


Asn Thr Ser Glu Trp Glu Gly Tyr Leu Pro Lys Glu Ser Ile Arg Thr 
                165                 170                 175     


Lys Ala Gly Pro Trp Gly Arg Cys Ala Val Val Ser Ser Ala Gly Ser 
            180                 185                 190         


Leu Lys Ser Ser Gln Leu Gly Arg Glu Ile Asp Asp His Asp Ala Val 
        195                 200                 205             


Leu Arg Phe Asn Gly Ala Pro Thr Ala Asn Phe Gln Gln Asp Val Gly 
    210                 215                 220                 


Thr Lys Thr Thr Ile Arg Leu Met Asn Ser Gln Leu Val Thr Thr Glu 
225                 230                 235                 240 


Lys Arg Phe Leu Lys Asp Ser Leu Tyr Asn Glu Gly Ile Leu Ile Val 
                245                 250                 255     


Trp Asp Pro Ser Val Tyr His Ser Asp Ile Pro Lys Trp Tyr Gln Asn 
            260                 265                 270         


Pro Asp Tyr Asn Phe Phe Asn Asn Tyr Lys Thr Tyr Arg Lys Leu His 
        275                 280                 285             


Pro Asn Gln Pro Phe Tyr Ile Leu Lys Pro Gln Met Pro Trp Glu Leu 
    290                 295                 300                 


Trp Asp Ile Leu Gln Glu Ile Ser Pro Glu Glu Ile Gln Pro Asn Pro 
305                 310                 315                 320 


Pro Ser Ser Gly Met Leu Gly Ile Ile Ile Met Met Thr Leu Cys Asp 
                325                 330                 335     


Gln Val Asp Ile Tyr Glu Phe Leu Pro Ser Lys Arg Lys Thr Asp Val 
            340                 345                 350         


Cys Tyr Tyr Tyr Gln Lys Phe Phe Asp Ser Ala Cys Thr Met Gly Ala 
        355                 360                 365             


Tyr His Pro Leu Leu Tyr Glu Lys Asn Leu Val Lys His Leu Asn Gln 
    370                 375                 380                 


Gly Thr Asp Glu Asp Ile Tyr Leu Leu Gly Lys Ala Thr Leu Pro Gly 
385                 390                 395                 400 


Phe Arg Thr Ile His Cys 
                405     


<210>  3056
<211>  175
<212>  PRT
<213>  homo sapiens

<400>  3056

Met Asn Ser Gln Leu Val Thr Thr Glu Lys Arg Phe Leu Lys Asp Ser 
1               5                   10                  15      


Leu Tyr Asn Glu Gly Ile Leu Ile Val Trp Asp Pro Ser Val Tyr His 
            20                  25                  30          


Ser Asp Ile Pro Lys Trp Tyr Gln Asn Pro Asp Tyr Asn Phe Phe Asn 
        35                  40                  45              


Asn Tyr Lys Thr Tyr Arg Lys Leu His Pro Asn Gln Pro Phe Tyr Ile 
    50                  55                  60                  


Leu Lys Pro Gln Met Pro Trp Glu Leu Trp Asp Ile Leu Gln Glu Ile 
65                  70                  75                  80  


Ser Pro Glu Glu Ile Gln Pro Asn Pro Pro Ser Ser Gly Met Leu Gly 
                85                  90                  95      


Ile Ile Ile Met Met Thr Leu Cys Asp Gln Val Asp Ile Tyr Glu Phe 
            100                 105                 110         


Leu Pro Ser Lys Arg Lys Thr Asp Val Cys Tyr Tyr Tyr Gln Lys Phe 
        115                 120                 125             


Phe Asp Ser Ala Cys Thr Met Gly Ala Tyr His Pro Leu Leu Tyr Glu 
    130                 135                 140                 


Lys Asn Leu Val Lys His Leu Asn Gln Gly Thr Asp Glu Asp Ile Tyr 
145                 150                 155                 160 


Leu Leu Gly Lys Ala Thr Leu Pro Gly Phe Arg Thr Ile His Cys 
                165                 170                 175 


<210>  3057
<211>  359
<212>  PRT
<213>  homo sapiens

<400>  3057

Met Arg Ser Ile Arg Lys Arg Trp Thr Ile Cys Thr Ile Ser Leu Leu 
1               5                   10                  15      


Leu Ile Phe Tyr Lys Thr Lys Glu Ile Ala Arg Thr Glu Glu His Gln 
            20                  25                  30          


Glu Thr Gln Leu Ile Gly Asp Gly Glu Leu Ser Leu Ser Arg Ser Leu 
        35                  40                  45              


Val Asn Ser Ser Asp Lys Ile Ile Arg Lys Ala Gly Ser Ser Ile Phe 
    50                  55                  60                  


Gln His Asn Val Glu Gly Trp Lys Ile Asn Ser Ser Leu Val Leu Glu 
65                  70                  75                  80  


Ile Arg Lys Asn Ile Leu Arg Phe Leu Asp Ala Glu Arg Asp Val Ser 
                85                  90                  95      


Val Val Lys Ser Ser Phe Lys Pro Gly Asp Val Ile His Tyr Val Leu 
            100                 105                 110         


Asp Arg Arg Arg Thr Leu Asn Ile Ser His Asp Leu His Ser Leu Leu 
        115                 120                 125             


Pro Glu Val Ser Pro Met Lys Asn Arg Arg Phe Lys Thr Cys Ala Val 
    130                 135                 140                 


Val Gly Asn Ser Gly Ile Leu Leu Asp Ser Glu Cys Gly Lys Glu Ile 
145                 150                 155                 160 


Asp Ser His Asn Phe Val Ile Arg Cys Asn Leu Ala Pro Val Val Glu 
                165                 170                 175     


Phe Ala Ala Asp Val Gly Thr Lys Ser Asp Phe Ile Thr Met Asn Pro 
            180                 185                 190         


Ser Val Val Gln Arg Ala Phe Gly Gly Phe Arg Asn Glu Ser Asp Arg 
        195                 200                 205             


Glu Lys Phe Val His Arg Leu Ser Met Leu Asn Asp Ser Val Leu Trp 
    210                 215                 220                 


Ile Pro Ala Phe Met Val Lys Gly Gly Glu Lys His Val Glu Trp Val 
225                 230                 235                 240 


Asn Ala Leu Ile Leu Lys Asn Lys Leu Lys Val Arg Thr Ala Tyr Pro 
                245                 250                 255     


Ser Leu Arg Leu Ile His Ala Val Arg Gly Tyr Trp Leu Thr Asn Lys 
            260                 265                 270         


Val Pro Ile Lys Arg Pro Ser Thr Gly Leu Leu Met Tyr Thr Leu Ala 
        275                 280                 285             


Thr Arg Phe Cys Asp Glu Ile His Leu Tyr Gly Phe Trp Pro Phe Pro 
    290                 295                 300                 


Lys Asp Leu Asn Gly Lys Ala Val Lys Tyr His Tyr Tyr Asp Asp Leu 
305                 310                 315                 320 


Lys Tyr Arg Tyr Phe Ser Asn Ala Ser Pro His Arg Met Pro Leu Glu 
                325                 330                 335     


Phe Lys Thr Leu Asn Val Leu His Asn Arg Gly Ala Leu Lys Leu Thr 
            340                 345                 350         


Thr Gly Lys Cys Val Lys Gln 
        355                 


<210>  3058
<211>  449
<212>  PRT
<213>  homo sapiens

<400>  3058

Met Met Leu Ser Thr Glu Gly Arg Glu Gly Phe Val Val Lys Val Arg 
1               5                   10                  15      


Gly Leu Pro Trp Ser Cys Ser Ala Asp Glu Val Met Arg Phe Phe Ser 
            20                  25                  30          


Asp Cys Lys Ile Gln Asn Gly Thr Ser Gly Ile Arg Phe Ile Tyr Thr 
        35                  40                  45              


Arg Glu Gly Arg Pro Ser Gly Glu Ala Phe Val Glu Leu Glu Ser Glu 
    50                  55                  60                  


Glu Glu Val Lys Leu Ala Leu Lys Lys Asp Arg Glu Thr Met Gly His 
65                  70                  75                  80  


Arg Tyr Val Glu Val Phe Lys Ser Asn Ser Val Glu Met Asp Trp Val 
                85                  90                  95      


Leu Lys His Thr Gly Pro Asn Ser Pro Asp Thr Ala Asn Asp Gly Phe 
            100                 105                 110         


Val Arg Leu Arg Gly Leu Pro Phe Gly Cys Ser Lys Glu Glu Ile Val 
        115                 120                 125             


Gln Phe Phe Ser Gly Leu Glu Ile Val Pro Asn Gly Met Thr Leu Pro 
    130                 135                 140                 


Val Asp Phe Gln Gly Arg Ser Thr Gly Glu Ala Phe Val Gln Phe Ala 
145                 150                 155                 160 


Ser Gln Glu Ile Ala Glu Lys Ala Leu Lys Lys His Lys Glu Arg Ile 
                165                 170                 175     


Gly His Arg Tyr Ile Glu Ile Phe Lys Ser Ser Arg Ala Glu Val Arg 
            180                 185                 190         


Thr His Tyr Asp Pro Pro Arg Lys Leu Met Ala Met Gln Arg Pro Gly 
        195                 200                 205             


Pro Tyr Asp Arg Pro Gly Ala Gly Arg Gly Tyr Asn Ser Ile Gly Arg 
    210                 215                 220                 


Gly Ala Gly Phe Glu Arg Met Arg Arg Gly Ala Tyr Gly Gly Gly Tyr 
225                 230                 235                 240 


Gly Gly Tyr Asp Asp Tyr Gly Gly Tyr Asn Asp Gly Tyr Gly Phe Gly 
                245                 250                 255     


Ser Asp Arg Phe Gly Arg Asp Leu Asn Tyr Cys Phe Ser Gly Met Ser 
            260                 265                 270         


Asp His Arg Tyr Gly Asp Gly Gly Ser Ser Phe Gln Ser Thr Thr Gly 
        275                 280                 285             


His Cys Val His Met Arg Gly Leu Pro Tyr Arg Ala Thr Glu Asn Asp 
    290                 295                 300                 


Ile Tyr Asn Phe Phe Ser Pro Leu Asn Pro Met Arg Val His Ile Glu 
305                 310                 315                 320 


Ile Gly Pro Asp Gly Arg Val Thr Gly Glu Ala Asp Val Glu Phe Ala 
                325                 330                 335     


Thr His Glu Asp Ala Val Ala Ala Met Ala Lys Asp Lys Ala Asn Met 
            340                 345                 350         


Gln His Arg Tyr Val Glu Leu Phe Leu Asn Ser Thr Ala Gly Thr Ser 
        355                 360                 365             


Gly Gly Ala Tyr Asp His Ser Tyr Val Glu Leu Phe Leu Asn Ser Thr 
    370                 375                 380                 


Ala Gly Ala Ser Gly Gly Ala Tyr Gly Ser Gln Met Met Gly Gly Met 
385                 390                 395                 400 


Gly Leu Ser Asn Gln Ser Ser Tyr Gly Gly Pro Ala Ser Gln Gln Leu 
                405                 410                 415     


Ser Gly Gly Tyr Gly Gly Gly Tyr Gly Gly Gln Ser Ser Met Ser Gly 
            420                 425                 430         


Tyr Asp Gln Val Leu Gln Glu Asn Ser Ser Asp Tyr Gln Ser Asn Leu 
        435                 440                 445             


Ala 
    


<210>  3059
<211>  773
<212>  PRT
<213>  homo sapiens

<400>  3059

Met Asp Val Thr Ser Ser Ser Gly Gly Gly Gly Asp Pro Arg Gln Ile 
1               5                   10                  15      


Glu Glu Thr Lys Pro Leu Leu Gly Gly Asp Val Ser Ala Pro Glu Gly 
            20                  25                  30          


Thr Lys Met Gly Ala Val Pro Cys Arg Arg Ala Leu Leu Leu Cys Asn 
        35                  40                  45              


Gly Met Arg Tyr Lys Leu Leu Gln Glu Gly Asp Ile Gln Val Cys Val 
    50                  55                  60                  


Ile Arg His Pro Arg Thr Phe Leu Ser Lys Ile Leu Thr Ser Lys Phe 
65                  70                  75                  80  


Leu Arg Arg Trp Glu Pro His His Leu Thr Leu Ala Asp Asn Ser Leu 
                85                  90                  95      


Ala Ser Ala Thr Pro Thr Gly Tyr Met Glu Asn Ser Val Ser Tyr Ser 
            100                 105                 110         


Ala Ile Glu Asp Val Gln Leu Leu Ser Trp Glu Asn Ala Pro Lys Tyr 
        115                 120                 125             


Cys Leu Gln Leu Thr Ile Pro Gly Gly Thr Val Leu Leu Gln Ala Ala 
    130                 135                 140                 


Asn Ser Tyr Leu Arg Asp Gln Trp Phe His Ser Leu Gln Trp Lys Lys 
145                 150                 155                 160 


Lys Ile Tyr Lys Tyr Lys Lys Val Leu Ser Asn Pro Ser Arg Trp Glu 
                165                 170                 175     


Val Val Leu Lys Glu Ile Arg Thr Leu Val Asp Met Ala Leu Thr Ser 
            180                 185                 190         


Pro Leu Gln Asp Asp Ser Ile Asn Gln Ala Pro Leu Glu Ile Val Ser 
        195                 200                 205             


Lys Leu Leu Ser Glu Asn Thr Asn Leu Thr Thr Gln Glu His Glu Asn 
    210                 215                 220                 


Ile Ile Val Ala Ile Ala Pro Leu Leu Glu Asn Asn His Pro Pro Pro 
225                 230                 235                 240 


Asp Leu Cys Glu Phe Phe Cys Lys His Cys Arg Glu Arg Pro Arg Ser 
                245                 250                 255     


Met Val Val Ile Glu Val Phe Thr Pro Val Val Gln Arg Ile Leu Lys 
            260                 265                 270         


His Asn Met Asp Phe Gly Lys Cys Pro Arg Leu Arg Leu Phe Thr Gln 
        275                 280                 285             


Glu Tyr Ile Leu Ala Leu Asn Glu Leu Asn Ala Gly Met Glu Val Val 
    290                 295                 300                 


Lys Lys Phe Ile Gln Ser Met His Gly Pro Thr Gly His Cys Pro His 
305                 310                 315                 320 


Pro Arg Val Leu Pro Asn Leu Val Ala Val Cys Leu Ala Ala Ile Tyr 
                325                 330                 335     


Ser Cys Tyr Glu Glu Phe Ile Asn Ser Arg Asp Asn Ser Pro Ser Leu 
            340                 345                 350         


Lys Glu Ile Arg Asn Gly Cys Gln Gln Pro Cys Asp Arg Lys Pro Thr 
        355                 360                 365             


Leu Pro Leu Arg Leu Leu His Pro Ser Pro Asp Leu Val Ser Gln Glu 
    370                 375                 380                 


Ala Thr Leu Ser Glu Ala Arg Leu Lys Ser Val Val Val Ala Ser Ser 
385                 390                 395                 400 


Glu Ile His Val Glu Val Glu Arg Thr Ser Thr Ala Lys Pro Ala Leu 
                405                 410                 415     


Thr Ala Ser Ala Gly Asn Asp Ser Glu Pro Asn Leu Ile Asp Cys Leu 
            420                 425                 430         


Met Val Ser Pro Ala Cys Ser Thr Met Ser Ile Glu Leu Gly Pro Gln 
        435                 440                 445             


Ala Asp Arg Thr Leu Gly Cys Tyr Val Glu Ile Leu Lys Leu Leu Ser 
    450                 455                 460                 


Asp Tyr Asp Asp Trp Arg Pro Ser Leu Ala Ser Leu Leu Gln Pro Ile 
465                 470                 475                 480 


Pro Phe Pro Lys Glu Ala Leu Ala His Glu Lys Phe Thr Lys Glu Leu 
                485                 490                 495     


Lys Tyr Val Ile Gln Arg Phe Ala Glu Asp Pro Arg Gln Glu Val His 
            500                 505                 510         


Ser Cys Leu Leu Ser Val Arg Ala Gly Lys Asp Gly Trp Phe Gln Leu 
        515                 520                 525             


Tyr Ser Pro Gly Gly Val Ala Cys Asp Asp Asp Gly Glu Leu Phe Ala 
    530                 535                 540                 


Ser Met Val His Ile Leu Met Gly Ser Cys Tyr Lys Thr Lys Lys Phe 
545                 550                 555                 560 


Leu Leu Ser Leu Ala Glu Asn Lys Leu Gly Pro Cys Met Leu Leu Ala 
                565                 570                 575     


Leu Arg Gly Asn Gln Thr Met Val Glu Ile Leu Cys Leu Met Leu Glu 
            580                 585                 590         


Tyr Asn Ile Ile Asp Asn Asn Asp Thr Gln Leu Gln Ile Ile Ser Thr 
        595                 600                 605             


Leu Glu Ser Thr Asp Val Gly Lys Arg Met Tyr Glu Gln Leu Cys Asp 
    610                 615                 620                 


Arg Gln Arg Glu Leu Lys Glu Leu Gln Arg Lys Gly Gly Pro Thr Arg 
625                 630                 635                 640 


Leu Thr Leu Pro Ser Lys Ser Thr Asp Ala Asp Leu Ala Arg Leu Leu 
                645                 650                 655     


Ser Ser Gly Ser Phe Gly Asn Leu Glu Asn Leu Ser Leu Ala Phe Thr 
            660                 665                 670         


Asn Val Thr Ser Ala Cys Ala Glu His Leu Ile Lys Leu Pro Ser Leu 
        675                 680                 685             


Lys Gln Leu Asn Leu Trp Ser Thr Gln Phe Gly Asp Ala Gly Leu Arg 
    690                 695                 700                 


Leu Leu Ser Glu His Leu Thr Met Leu Gln Val Leu Asn Leu Cys Glu 
705                 710                 715                 720 


Thr Pro Val Thr Asp Ala Gly Leu Leu Ala Leu Ser Ser Met Lys Ser 
                725                 730                 735     


Leu Cys Ser Leu Asn Met Asn Ser Thr Lys Leu Ser Ala Asp Thr Tyr 
            740                 745                 750         


Glu Asp Leu Lys Ala Lys Leu Pro Asn Leu Lys Glu Val Asp Val Arg 
        755                 760                 765             


Tyr Thr Glu Ala Trp 
    770             


<210>  3060
<211>  1872
<212>  PRT
<213>  homo sapiens

<400>  3060

Met Met Asn Glu Asp Ala Ala Gln Lys Ser Asp Ser Gly Glu Lys Phe 
1               5                   10                  15      


Asn Gly Ser Ser Gln Arg Arg Lys Arg Pro Lys Lys Ser Asp Ser Asn 
            20                  25                  30          


Ala Ser Phe Leu Arg Ala Ala Arg Ala Gly Asn Leu Asp Lys Val Val 
        35                  40                  45              


Glu Tyr Leu Lys Gly Gly Ile Asp Ile Asn Thr Cys Asn Gln Asn Gly 
    50                  55                  60                  


Leu Asn Ala Leu His Leu Ala Ala Lys Glu Gly His Val Gly Leu Val 
65                  70                  75                  80  


Gln Glu Leu Leu Gly Arg Gly Ser Ser Val Asp Ser Ala Thr Lys Lys 
                85                  90                  95      


Gly Asn Thr Ala Leu His Ile Ala Ser Leu Ala Gly Gln Ala Glu Val 
            100                 105                 110         


Val Lys Val Leu Val Lys Glu Gly Ala Asn Ile Asn Ala Gln Ser Gln 
        115                 120                 125             


Asn Gly Phe Thr Pro Leu Tyr Met Ala Ala Gln Glu Asn His Ile Asp 
    130                 135                 140                 


Val Val Lys Tyr Leu Leu Glu Asn Gly Ala Asn Gln Ser Thr Ala Thr 
145                 150                 155                 160 


Glu Asp Gly Phe Thr Pro Leu Ala Val Ala Leu Gln Gln Gly His Asn 
                165                 170                 175     


Gln Ala Val Ala Ile Leu Leu Glu Asn Asp Thr Lys Gly Lys Val Arg 
            180                 185                 190         


Leu Pro Ala Leu His Ile Ala Ala Arg Lys Asp Asp Thr Lys Ser Ala 
        195                 200                 205             


Ala Leu Leu Leu Gln Asn Asp His Asn Ala Asp Val Gln Ser Lys Met 
    210                 215                 220                 


Met Val Asn Arg Thr Thr Glu Ser Gly Phe Thr Pro Leu His Ile Ala 
225                 230                 235                 240 


Ala His Tyr Gly Asn Val Asn Val Ala Thr Leu Leu Leu Asn Arg Gly 
                245                 250                 255     


Ala Ala Val Asp Phe Thr Ala Arg Asn Gly Ile Thr Pro Leu His Val 
            260                 265                 270         


Ala Ser Lys Arg Gly Asn Thr Asn Met Val Lys Leu Leu Leu Asp Arg 
        275                 280                 285             


Gly Gly Gln Ile Asp Ala Lys Thr Arg Asp Gly Leu Thr Pro Leu His 
    290                 295                 300                 


Cys Ala Ala Arg Ser Gly His Asp Gln Val Val Glu Leu Leu Leu Glu 
305                 310                 315                 320 


Arg Gly Ala Pro Leu Leu Ala Arg Thr Lys Asn Gly Leu Ser Pro Leu 
                325                 330                 335     


His Met Ala Ala Gln Gly Asp His Val Glu Cys Val Lys His Leu Leu 
            340                 345                 350         


Gln His Lys Ala Pro Val Asp Asp Val Thr Leu Asp Tyr Leu Thr Ala 
        355                 360                 365             


Leu His Val Ala Ala His Cys Gly His Tyr Arg Val Thr Lys Leu Leu 
    370                 375                 380                 


Leu Asp Lys Arg Ala Asn Pro Asn Ala Arg Ala Leu Asn Gly Phe Thr 
385                 390                 395                 400 


Pro Leu His Ile Ala Cys Lys Lys Asn Arg Ile Lys Val Met Glu Leu 
                405                 410                 415     


Leu Val Lys Tyr Gly Ala Ser Ile Gln Ala Ile Thr Glu Ser Gly Leu 
            420                 425                 430         


Thr Pro Ile His Val Ala Ala Phe Met Gly His Leu Asn Ile Val Leu 
        435                 440                 445             


Leu Leu Leu Gln Asn Gly Ala Ser Pro Asp Val Thr Asn Ile Arg Gly 
    450                 455                 460                 


Glu Thr Ala Leu His Met Ala Ala Arg Ala Gly Gln Val Glu Val Val 
465                 470                 475                 480 


Arg Cys Leu Leu Arg Asn Gly Ala Leu Val Asp Ala Arg Ala Arg Glu 
                485                 490                 495     


Glu Gln Thr Pro Leu His Ile Ala Ser Arg Leu Gly Lys Thr Glu Ile 
            500                 505                 510         


Val Gln Leu Leu Leu Gln His Met Ala His Pro Asp Ala Ala Thr Thr 
        515                 520                 525             


Asn Gly Tyr Thr Pro Leu His Ile Ser Ala Arg Glu Gly Gln Val Asp 
    530                 535                 540                 


Val Ala Ser Val Leu Leu Glu Ala Gly Ala Ala His Ser Leu Ala Thr 
545                 550                 555                 560 


Lys Lys Gly Phe Thr Pro Leu His Val Ala Ala Lys Tyr Gly Ser Leu 
                565                 570                 575     


Asp Val Ala Lys Leu Leu Leu Gln Arg Arg Ala Ala Ala Asp Ser Ala 
            580                 585                 590         


Gly Lys Asn Gly Leu Thr Pro Leu His Val Ala Ala His Tyr Asp Asn 
        595                 600                 605             


Gln Lys Val Ala Leu Leu Leu Leu Glu Lys Gly Ala Ser Pro His Ala 
    610                 615                 620                 


Thr Ala Lys Asn Gly Tyr Thr Pro Leu His Ile Ala Ala Lys Lys Asn 
625                 630                 635                 640 


Gln Met Gln Ile Ala Ser Thr Leu Leu Asn Tyr Gly Ala Glu Thr Asn 
                645                 650                 655     


Ile Val Thr Lys Gln Gly Val Thr Pro Leu His Leu Ala Ser Gln Glu 
            660                 665                 670         


Gly His Thr Asp Met Val Thr Leu Leu Leu Asp Lys Gly Ala Asn Ile 
        675                 680                 685             


His Met Ser Thr Lys Ser Gly Leu Thr Ser Leu His Leu Ala Ala Gln 
    690                 695                 700                 


Glu Asp Lys Val Asn Val Ala Asp Ile Leu Thr Lys His Gly Ala Asp 
705                 710                 715                 720 


Gln Asp Ala His Thr Lys Leu Gly Tyr Thr Pro Leu Ile Val Ala Cys 
                725                 730                 735     


His Tyr Gly Asn Val Lys Met Val Asn Phe Leu Leu Lys Gln Gly Ala 
            740                 745                 750         


Asn Val Asn Ala Lys Thr Lys Asn Gly Tyr Thr Pro Leu His Gln Ala 
        755                 760                 765             


Ala Gln Gln Gly His Thr His Ile Ile Asn Val Leu Leu Gln His Gly 
    770                 775                 780                 


Ala Lys Pro Asn Ala Thr Thr Ala Asn Gly Asn Thr Ala Leu Ala Ile 
785                 790                 795                 800 


Ala Lys Arg Leu Gly Tyr Ile Ser Val Val Asp Thr Leu Lys Val Val 
                805                 810                 815     


Thr Glu Glu Val Thr Thr Thr Thr Thr Thr Ile Thr Glu Lys His Lys 
            820                 825                 830         


Leu Asn Val Pro Glu Thr Met Thr Glu Val Leu Asp Val Ser Asp Glu 
        835                 840                 845             


Glu Gly Asp Asp Thr Met Thr Gly Asp Gly Gly Glu Tyr Leu Arg Pro 
    850                 855                 860                 


Glu Asp Leu Lys Glu Leu Gly Asp Asp Ser Leu Pro Ser Ser Gln Phe 
865                 870                 875                 880 


Leu Asp Gly Met Asn Tyr Leu Arg Tyr Ser Leu Glu Gly Gly Arg Ser 
                885                 890                 895     


Asp Ser Leu Arg Ser Phe Ser Ser Asp Arg Ser His Thr Leu Ser His 
            900                 905                 910         


Ala Ser Tyr Leu Arg Asp Ser Ala Val Met Asp Asp Ser Val Val Ile 
        915                 920                 925             


Pro Ser His Gln Val Ser Thr Leu Ala Lys Glu Ala Glu Arg Asn Ser 
    930                 935                 940                 


Tyr Arg Leu Ser Trp Gly Thr Glu Asn Leu Asp Asn Val Ala Leu Ser 
945                 950                 955                 960 


Ser Ser Pro Ile His Ser Gly Phe Leu Val Ser Phe Met Val Asp Ala 
                965                 970                 975     


Arg Gly Gly Ala Met Arg Gly Cys Arg His Asn Gly Leu Arg Ile Ile 
            980                 985                 990         


Ile Pro Pro Arg Lys Cys Thr Ala  Pro Thr Arg Val Thr  Cys Arg Leu 
        995                 1000                 1005             


Val Lys  Arg His Arg Leu Ala  Thr Met Pro Pro Met  Val Glu Gly 
    1010                 1015                 1020             


Glu Gly  Leu Ala Ser Arg Leu  Ile Glu Val Gly Pro  Ser Gly Ala 
    1025                 1030                 1035             


Gln Phe  Leu Gly Lys Leu His  Leu Pro Thr Ala Pro  Pro Pro Leu 
    1040                 1045                 1050             


Asn Glu  Gly Glu Ser Leu Val  Ser Arg Ile Leu Gln  Leu Gly Pro 
    1055                 1060                 1065             


Pro Gly  Thr Lys Phe Leu Gly  Pro Val Ile Val Glu  Ile Pro His 
    1070                 1075                 1080             


Phe Ala  Ala Leu Arg Gly Lys  Glu Arg Glu Leu Val  Val Leu Arg 
    1085                 1090                 1095             


Ser Glu  Asn Gly Asp Ser Trp  Lys Glu His Phe Cys  Asp Tyr Thr 
    1100                 1105                 1110             


Glu Asp  Glu Leu Asn Glu Ile  Leu Asn Gly Met Asp  Glu Val Leu 
    1115                 1120                 1125             


Asp Ser  Pro Glu Asp Leu Glu  Lys Lys Arg Ile Cys  Arg Ile Ile 
    1130                 1135                 1140             


Thr Arg  Asp Phe Pro Gln Tyr  Phe Ala Val Val Ser  Arg Ile Lys 
    1145                 1150                 1155             


Gln Asp  Ser Asn Leu Ile Gly  Pro Glu Gly Gly Val  Leu Ser Ser 
    1160                 1165                 1170             


Thr Val  Val Pro Gln Val Gln  Ala Val Phe Pro Glu  Gly Ala Leu 
    1175                 1180                 1185             


Thr Lys  Arg Ile Arg Val Gly  Leu Gln Ala Gln Pro  Met His Ser 
    1190                 1195                 1200             


Glu Leu  Val Lys Lys Ile Leu  Gly Asn Lys Ala Thr  Phe Ser Pro 
    1205                 1210                 1215             


Ile Val  Thr Leu Glu Pro Arg  Arg Arg Lys Phe His  Lys Pro Ile 
    1220                 1225                 1230             


Thr Met  Thr Ile Pro Val Pro  Lys Ala Ser Ser Asp  Val Met Leu 
    1235                 1240                 1245             


Asn Gly  Phe Gly Gly Asp Ala  Pro Thr Leu Arg Leu  Leu Cys Ser 
    1250                 1255                 1260             


Ile Thr  Gly Gly Thr Thr Pro  Ala Gln Trp Glu Asp  Ile Thr Gly 
    1265                 1270                 1275             


Thr Thr  Pro Leu Thr Phe Val  Asn Glu Cys Val Ser  Phe Thr Thr 
    1280                 1285                 1290             


Asn Val  Ser Ala Arg Phe Trp  Leu Ile Asp Cys Arg  Gln Ile Gln 
    1295                 1300                 1305             


Glu Ser  Val Thr Phe Ala Ser  Gln Val Tyr Arg Glu  Ile Ile Cys 
    1310                 1315                 1320             


Val Pro  Tyr Met Ala Lys Phe  Val Val Phe Ala Lys  Ser His Asp 
    1325                 1330                 1335             


Pro Ile  Glu Ala Arg Leu Arg  Cys Phe Cys Met Thr  Asp Asp Lys 
    1340                 1345                 1350             


Val Asp  Lys Thr Leu Glu Gln  Gln Glu Asn Phe Ala  Glu Val Ala 
    1355                 1360                 1365             


Arg Ser  Arg Asp Val Glu Val  Leu Glu Gly Lys Pro  Ile Tyr Val 
    1370                 1375                 1380             


Asp Cys  Phe Gly Asn Leu Val  Pro Leu Thr Lys Ser  Gly Gln His 
    1385                 1390                 1395             


His Ile  Phe Ser Phe Phe Ala  Phe Lys Glu Asn Arg  Leu Pro Leu 
    1400                 1405                 1410             


Phe Val  Lys Val Arg Asp Thr  Thr Gln Glu Pro Cys  Gly Arg Leu 
    1415                 1420                 1425             


Ser Phe  Met Lys Glu Pro Lys  Ser Thr Arg Gly Leu  Val His Gln 
    1430                 1435                 1440             


Ala Ile  Cys Asn Leu Asn Ile  Thr Leu Pro Ile Tyr  Thr Lys Glu 
    1445                 1450                 1455             


Ser Glu  Ser Asp Gln Glu Gln  Glu Glu Glu Ile Asp  Met Thr Ser 
    1460                 1465                 1470             


Glu Lys  Asn Pro Gln Asp Glu  Gln Glu Arg Ile Glu  Glu Arg Leu 
    1475                 1480                 1485             


Ala Tyr  Ile Ala Asp His Leu  Gly Phe Ser Trp Thr  Glu Leu Ala 
    1490                 1495                 1500             


Arg Glu  Leu Asp Phe Thr Glu  Glu Gln Ile His Gln  Ile Arg Ile 
    1505                 1510                 1515             


Glu Asn  Pro Asn Ser Leu Gln  Asp Gln Ser His Ala  Leu Leu Lys 
    1520                 1525                 1530             


Tyr Trp  Leu Glu Arg Asp Gly  Lys His Ala Thr Asp  Thr Asn Leu 
    1535                 1540                 1545             


Val Glu  Cys Leu Thr Lys Ile  Asn Arg Met Asp Ile  Val His Leu 
    1550                 1555                 1560             


Met Glu  Thr Asn Thr Glu Pro  Leu Gln Glu Arg Ile  Ser His Ser 
    1565                 1570                 1575             


Tyr Ala  Glu Ile Glu Gln Thr  Ile Thr Leu Asp His  Ser Glu Gly 
    1580                 1585                 1590             


Phe Ser  Val Leu Gln Glu Glu  Leu Cys Thr Ala Gln  His Lys Gln 
    1595                 1600                 1605             


Lys Glu  Glu Gln Ala Val Ser  Lys Glu Ser Glu Thr  Cys Asp His 
    1610                 1615                 1620             


Pro Pro  Ile Val Ser Glu Glu  Asp Ile Ser Val Gly  Tyr Ser Thr 
    1625                 1630                 1635             


Phe Gln  Asp Gly Val Pro Lys  Thr Glu Gly Asp Ser  Ser Ala Thr 
    1640                 1645                 1650             


Ala Leu  Phe Pro Gln Thr His  Lys Glu Gln Val Gln  Gln Asp Phe 
    1655                 1660                 1665             


Ser Gly  Lys Met Gln Asp Leu  Pro Glu Glu Ser Ser  Leu Glu Tyr 
    1670                 1675                 1680             


Gln Gln  Glu Tyr Phe Val Thr  Thr Pro Gly Thr Glu  Thr Ser Glu 
    1685                 1690                 1695             


Thr Gln  Lys Ala Met Ile Val  Pro Ser Ser Pro Ser  Lys Thr Pro 
    1700                 1705                 1710             


Glu Glu  Val Ser Thr Pro Ala  Glu Glu Glu Lys Leu  Tyr Leu Gln 
    1715                 1720                 1725             


Thr Pro  Thr Ser Ser Glu Arg  Gly Gly Ser Pro Ile  Ile Gln Glu 
    1730                 1735                 1740             


Pro Glu  Glu Pro Ser Glu His  Arg Glu Glu Ser Ser  Pro Arg Lys 
    1745                 1750                 1755             


Thr Ser  Leu Val Ile Val Glu  Ser Ala Asp Asn Gln  Pro Glu Thr 
    1760                 1765                 1770             


Cys Glu  Arg Leu Asp Glu Asp  Ala Ala Phe Glu Lys  Gly Asp Asp 
    1775                 1780                 1785             


Met Pro  Glu Ile Pro Pro Glu  Thr Val Thr Glu Glu  Glu Tyr Ile 
    1790                 1795                 1800             


Asp Glu  His Gly His Thr Val  Val Lys Lys Val Thr  Arg Lys Ile 
    1805                 1810                 1815             


Ile Arg  Arg Tyr Val Ser Ser  Glu Gly Thr Glu Lys  Glu Glu Ile 
    1820                 1825                 1830             


Met Val  Gln Gly Met Pro Gln  Glu Pro Val Asn Ile  Glu Glu Gly 
    1835                 1840                 1845             


Asp Gly  Tyr Ser Lys Val Ile  Lys Arg Val Val Leu  Lys Ser Asp 
    1850                 1855                 1860             


Thr Glu  Gln Ser Glu Asp Asn  Asn Glu 
    1865                 1870         


<210>  3061
<211>  554
<212>  PRT
<213>  homo sapiens

<400>  3061

Met Gln Met Cys Arg Pro Ala Ser Ser Ser Val Leu Tyr Val Pro Thr 
1               5                   10                  15      


Arg Trp Pro Gly Gly Cys Gly Ala Thr Trp Gln Ser Cys Pro Ser Pro 
            20                  25                  30          


Pro Pro Arg Arg Thr Arg Ile Pro Gln Arg Pro Ala Val Met Tyr Ser 
        35                  40                  45              


Pro Leu Cys Leu Thr Gln Asp Glu Phe His Pro Phe Ile Glu Ala Leu 
    50                  55                  60                  


Leu Pro His Val Arg Ala Phe Ala Tyr Thr Trp Phe Asn Leu Gln Ala 
65                  70                  75                  80  


Arg Lys Arg Lys Tyr Phe Lys Lys His Glu Lys Arg Met Ser Lys Glu 
                85                  90                  95      


Glu Glu Arg Ala Val Lys Asp Glu Leu Leu Ser Glu Lys Pro Glu Val 
            100                 105                 110         


Lys Gln Lys Trp Ala Ser Arg Leu Leu Ala Lys Leu Arg Lys Asp Ile 
        115                 120                 125             


Arg Pro Glu Tyr Arg Glu Asp Phe Val Leu Thr Val Thr Gly Lys Lys 
    130                 135                 140                 


Pro Pro Cys Cys Val Leu Ser Asn Pro Asp Gln Lys Gly Lys Met Arg 
145                 150                 155                 160 


Arg Ile Asp Cys Leu Arg Gln Ala Asp Lys Val Trp Arg Leu Asp Leu 
                165                 170                 175     


Val Met Val Ile Leu Phe Lys Gly Ile Pro Leu Glu Ser Thr Asp Gly 
            180                 185                 190         


Glu Arg Leu Val Lys Ser Pro Gln Cys Ser Asn Pro Gly Leu Cys Val 
        195                 200                 205             


Gln Pro His His Ile Gly Val Ser Val Lys Glu Leu Asp Leu Tyr Leu 
    210                 215                 220                 


Ala Tyr Phe Val His Ala Ala Asp Ser Ser Gln Ser Glu Ser Pro Ser 
225                 230                 235                 240 


Gln Pro Ser Asp Ala Asp Ile Lys Asp Gln Pro Glu Asn Gly His Leu 
                245                 250                 255     


Gly Phe Gln Asp Ser Phe Val Thr Ser Gly Val Phe Ser Val Thr Glu 
            260                 265                 270         


Leu Val Arg Val Ser Gln Thr Pro Ile Ala Ala Gly Thr Gly Pro Asn 
        275                 280                 285             


Phe Ser Leu Ser Asp Leu Glu Ser Ser Ser Tyr Tyr Ser Met Ser Pro 
    290                 295                 300                 


Gly Ala Met Arg Arg Ser Leu Pro Ser Thr Ser Ser Thr Ser Ser Thr 
305                 310                 315                 320 


Lys Arg Leu Lys Ser Val Glu Asp Glu Met Asp Ser Pro Gly Glu Glu 
                325                 330                 335     


Pro Phe Tyr Thr Gly Gln Gly Arg Ser Pro Gly Ser Gly Ser Gln Ser 
            340                 345                 350         


Ser Gly Trp His Glu Val Glu Pro Gly Met Pro Ser Pro Thr Thr Leu 
        355                 360                 365             


Lys Lys Ser Glu Lys Ser Gly Phe Ser Ser Pro Ser Pro Ser Gln Thr 
    370                 375                 380                 


Ser Ser Leu Gly Thr Ala Phe Thr Gln His His Arg Pro Val Ile Thr 
385                 390                 395                 400 


Gly Pro Arg Ala Ser Pro His Ala Thr Pro Ser Thr Leu His Phe Pro 
                405                 410                 415     


Thr Ser Pro Ile Ile Gln Gln Pro Gly Pro Tyr Phe Ser His Pro Ala 
            420                 425                 430         


Ile Arg Tyr His Pro Gln Glu Thr Leu Lys Glu Phe Val Gln Leu Val 
        435                 440                 445             


Cys Pro Asp Ala Gly Gln Gln Ala Gly Gln Val Gly Phe Leu Asn Pro 
    450                 455                 460                 


Asn Gly Ser Ser Gln Gly Lys Val His Asn Pro Phe Leu Pro Thr Pro 
465                 470                 475                 480 


Met Leu Pro Pro Pro Pro Pro Pro Pro Met Ala Arg Pro Val Pro Leu 
                485                 490                 495     


Pro Val Pro Asp Thr Lys Pro Pro Thr Thr Ser Thr Glu Gly Gly Ala 
            500                 505                 510         


Ala Ser Pro Thr Ser Pro Thr Tyr Ser Thr Pro Ser Thr Ser Pro Ala 
        515                 520                 525             


Asn Arg Phe Val Ser Val Gly Pro Arg Asp Pro Ser Phe Val Asn Ile 
    530                 535                 540                 


Pro Gln Gln Thr Gln Ser Trp Tyr Leu Gly 
545                 550                 


<210>  3062
<211>  1863
<212>  PRT
<213>  homo sapiens

<400>  3062

Met Thr Thr Met Leu Gln Lys Ser Asp Ser Asn Ala Ser Phe Leu Arg 
1               5                   10                  15      


Ala Ala Arg Ala Gly Asn Leu Asp Lys Val Val Glu Tyr Leu Lys Gly 
            20                  25                  30          


Gly Ile Asp Ile Asn Thr Cys Asn Gln Asn Gly Leu Asn Ala Leu His 
        35                  40                  45              


Leu Ala Ala Lys Glu Gly His Val Gly Leu Val Gln Glu Leu Leu Gly 
    50                  55                  60                  


Arg Gly Ser Ser Val Asp Ser Ala Thr Lys Lys Gly Asn Thr Ala Leu 
65                  70                  75                  80  


His Ile Ala Ser Leu Ala Gly Gln Ala Glu Val Val Lys Val Leu Val 
                85                  90                  95      


Lys Glu Gly Ala Asn Ile Asn Ala Gln Ser Gln Asn Gly Phe Thr Pro 
            100                 105                 110         


Leu Tyr Met Ala Ala Gln Glu Asn His Ile Asp Val Val Lys Tyr Leu 
        115                 120                 125             


Leu Glu Asn Gly Ala Asn Gln Ser Thr Ala Thr Glu Asp Gly Phe Thr 
    130                 135                 140                 


Pro Leu Ala Val Ala Leu Gln Gln Gly His Asn Gln Ala Val Ala Ile 
145                 150                 155                 160 


Leu Leu Glu Asn Asp Thr Lys Gly Lys Val Arg Leu Pro Ala Leu His 
                165                 170                 175     


Ile Ala Ala Arg Lys Asp Asp Thr Lys Ser Ala Ala Leu Leu Leu Gln 
            180                 185                 190         


Asn Asp His Asn Ala Asp Val Gln Ser Lys Met Met Val Asn Arg Thr 
        195                 200                 205             


Thr Glu Ser Gly Phe Thr Pro Leu His Ile Ala Ala His Tyr Gly Asn 
    210                 215                 220                 


Val Asn Val Ala Thr Leu Leu Leu Asn Arg Gly Ala Ala Val Asp Phe 
225                 230                 235                 240 


Thr Ala Arg Asn Gly Ile Thr Pro Leu His Val Ala Ser Lys Arg Gly 
                245                 250                 255     


Asn Thr Asn Met Val Lys Leu Leu Leu Asp Arg Gly Gly Gln Ile Asp 
            260                 265                 270         


Ala Lys Thr Arg Asp Gly Leu Thr Pro Leu His Cys Ala Ala Arg Ser 
        275                 280                 285             


Gly His Asp Gln Val Val Glu Leu Leu Leu Glu Arg Gly Ala Pro Leu 
    290                 295                 300                 


Leu Ala Arg Thr Lys Asn Gly Leu Ser Pro Leu His Met Ala Ala Gln 
305                 310                 315                 320 


Gly Asp His Val Glu Cys Val Lys His Leu Leu Gln His Lys Ala Pro 
                325                 330                 335     


Val Asp Asp Val Thr Leu Asp Tyr Leu Thr Ala Leu His Val Ala Ala 
            340                 345                 350         


His Cys Gly His Tyr Arg Val Thr Lys Leu Leu Leu Asp Lys Arg Ala 
        355                 360                 365             


Asn Pro Asn Ala Arg Ala Leu Asn Gly Phe Thr Pro Leu His Ile Ala 
    370                 375                 380                 


Cys Lys Lys Asn Arg Ile Lys Val Met Glu Leu Leu Val Lys Tyr Gly 
385                 390                 395                 400 


Ala Ser Ile Gln Ala Ile Thr Glu Ser Gly Leu Thr Pro Ile His Val 
                405                 410                 415     


Ala Ala Phe Met Gly His Leu Asn Ile Val Leu Leu Leu Leu Gln Asn 
            420                 425                 430         


Gly Ala Ser Pro Asp Val Thr Asn Ile Arg Gly Glu Thr Ala Leu His 
        435                 440                 445             


Met Ala Ala Arg Ala Gly Gln Val Glu Val Val Arg Cys Leu Leu Arg 
    450                 455                 460                 


Asn Gly Ala Leu Val Asp Ala Arg Ala Arg Glu Glu Gln Thr Pro Leu 
465                 470                 475                 480 


His Ile Ala Ser Arg Leu Gly Lys Thr Glu Ile Val Gln Leu Leu Leu 
                485                 490                 495     


Gln His Met Ala His Pro Asp Ala Ala Thr Thr Asn Gly Tyr Thr Pro 
            500                 505                 510         


Leu His Ile Ser Ala Arg Glu Gly Gln Val Asp Val Ala Ser Val Leu 
        515                 520                 525             


Leu Glu Ala Gly Ala Ala His Ser Leu Ala Thr Lys Lys Gly Phe Thr 
    530                 535                 540                 


Pro Leu His Val Ala Ala Lys Tyr Gly Ser Leu Asp Val Ala Lys Leu 
545                 550                 555                 560 


Leu Leu Gln Arg Arg Ala Ala Ala Asp Ser Ala Gly Lys Asn Gly Leu 
                565                 570                 575     


Thr Pro Leu His Val Ala Ala His Tyr Asp Asn Gln Lys Val Ala Leu 
            580                 585                 590         


Leu Leu Leu Glu Lys Gly Ala Ser Pro His Ala Thr Ala Lys Asn Gly 
        595                 600                 605             


Tyr Thr Pro Leu His Ile Ala Ala Lys Lys Asn Gln Met Gln Ile Ala 
    610                 615                 620                 


Ser Thr Leu Leu Asn Tyr Gly Ala Glu Thr Asn Ile Val Thr Lys Gln 
625                 630                 635                 640 


Gly Val Thr Pro Leu His Leu Ala Ser Gln Glu Gly His Thr Asp Met 
                645                 650                 655     


Val Thr Leu Leu Leu Asp Lys Gly Ala Asn Ile His Met Ser Thr Lys 
            660                 665                 670         


Ser Gly Leu Thr Ser Leu His Leu Ala Ala Gln Glu Asp Lys Val Asn 
        675                 680                 685             


Val Ala Asp Ile Leu Thr Lys His Gly Ala Asp Gln Asp Ala His Thr 
    690                 695                 700                 


Lys Leu Gly Tyr Thr Pro Leu Ile Val Ala Cys His Tyr Gly Asn Val 
705                 710                 715                 720 


Lys Met Val Asn Phe Leu Leu Lys Gln Gly Ala Asn Val Asn Ala Lys 
                725                 730                 735     


Thr Lys Asn Gly Tyr Thr Pro Leu His Gln Ala Ala Gln Gln Gly His 
            740                 745                 750         


Thr His Ile Ile Asn Val Leu Leu Gln His Gly Ala Lys Pro Asn Ala 
        755                 760                 765             


Thr Thr Ala Asn Gly Asn Thr Ala Leu Ala Ile Ala Lys Arg Leu Gly 
    770                 775                 780                 


Tyr Ile Ser Val Val Asp Thr Leu Lys Val Val Thr Glu Glu Val Thr 
785                 790                 795                 800 


Thr Thr Thr Thr Thr Ile Thr Glu Lys His Lys Leu Asn Val Pro Glu 
                805                 810                 815     


Thr Met Thr Glu Val Leu Asp Val Ser Asp Glu Glu Gly Asp Asp Thr 
            820                 825                 830         


Met Thr Gly Asp Gly Gly Glu Tyr Leu Arg Pro Glu Asp Leu Lys Glu 
        835                 840                 845             


Leu Gly Asp Asp Ser Leu Pro Ser Ser Gln Phe Leu Asp Gly Met Asn 
    850                 855                 860                 


Tyr Leu Arg Tyr Ser Leu Glu Gly Gly Arg Ser Asp Ser Leu Arg Ser 
865                 870                 875                 880 


Phe Ser Ser Asp Arg Ser His Thr Leu Ser His Ala Ser Tyr Leu Arg 
                885                 890                 895     


Asp Ser Ala Val Met Asp Asp Ser Val Val Ile Pro Ser His Gln Val 
            900                 905                 910         


Ser Thr Leu Ala Lys Glu Ala Glu Arg Asn Ser Tyr Arg Leu Ser Trp 
        915                 920                 925             


Gly Thr Glu Asn Leu Asp Asn Val Ala Leu Ser Ser Ser Pro Ile His 
    930                 935                 940                 


Ser Gly Arg Ala Ser Pro Cys Leu Glu Arg Asp Asn Ser Ser Phe Leu 
945                 950                 955                 960 


Val Ser Phe Met Val Asp Ala Arg Gly Gly Ala Met Arg Gly Cys Arg 
                965                 970                 975     


His Asn Gly Leu Arg Ile Ile Ile Pro Pro Arg Lys Cys Thr Ala Pro 
            980                 985                 990         


Thr Arg Val Thr Cys Arg Leu Val  Lys Arg His Arg Leu  Ala Thr Met 
        995                 1000                 1005             


Pro Pro  Met Val Glu Gly Glu  Gly Leu Ala Ser Arg  Leu Ile Glu 
    1010                 1015                 1020             


Val Gly  Pro Ser Gly Ala Gln  Phe Leu Gly Lys Leu  His Leu Pro 
    1025                 1030                 1035             


Thr Ala  Pro Pro Pro Leu Asn  Glu Gly Glu Ser Leu  Val Ser Arg 
    1040                 1045                 1050             


Ile Leu  Gln Leu Gly Pro Pro  Gly Thr Lys Phe Leu  Gly Pro Val 
    1055                 1060                 1065             


Ile Val  Glu Ile Pro His Phe  Ala Ala Leu Arg Gly  Lys Glu Arg 
    1070                 1075                 1080             


Glu Leu  Val Val Leu Arg Ser  Glu Asn Gly Asp Ser  Trp Lys Glu 
    1085                 1090                 1095             


His Phe  Cys Asp Tyr Thr Glu  Asp Glu Leu Asn Glu  Ile Leu Asn 
    1100                 1105                 1110             


Gly Met  Asp Glu Val Leu Asp  Ser Pro Glu Asp Leu  Glu Lys Lys 
    1115                 1120                 1125             


Arg Ile  Cys Arg Ile Ile Thr  Arg Asp Phe Pro Gln  Tyr Phe Ala 
    1130                 1135                 1140             


Val Val  Ser Arg Ile Lys Gln  Asp Ser Asn Leu Ile  Gly Pro Glu 
    1145                 1150                 1155             


Gly Gly  Val Leu Ser Ser Thr  Val Val Pro Gln Val  Gln Ala Val 
    1160                 1165                 1170             


Phe Pro  Glu Gly Ala Leu Thr  Lys Arg Ile Arg Val  Gly Leu Gln 
    1175                 1180                 1185             


Ala Gln  Pro Met His Ser Glu  Leu Val Lys Lys Ile  Leu Gly Asn 
    1190                 1195                 1200             


Lys Ala  Thr Phe Ser Pro Ile  Val Thr Leu Glu Pro  Arg Arg Arg 
    1205                 1210                 1215             


Lys Phe  His Lys Pro Ile Thr  Met Thr Ile Pro Val  Pro Lys Ala 
    1220                 1225                 1230             


Ser Ser  Asp Val Met Leu Asn  Gly Phe Gly Gly Asp  Ala Pro Thr 
    1235                 1240                 1245             


Leu Arg  Leu Leu Cys Ser Ile  Thr Gly Gly Thr Thr  Pro Ala Gln 
    1250                 1255                 1260             


Trp Glu  Asp Ile Thr Gly Thr  Thr Pro Leu Thr Phe  Val Asn Glu 
    1265                 1270                 1275             


Cys Val  Ser Phe Thr Thr Asn  Val Ser Ala Arg Phe  Trp Leu Ile 
    1280                 1285                 1290             


Asp Cys  Arg Gln Ile Gln Glu  Ser Val Thr Phe Ala  Ser Gln Val 
    1295                 1300                 1305             


Tyr Arg  Glu Ile Ile Cys Val  Pro Tyr Met Ala Lys  Phe Val Val 
    1310                 1315                 1320             


Phe Ala  Lys Ser His Asp Pro  Ile Glu Ala Arg Leu  Arg Cys Phe 
    1325                 1330                 1335             


Cys Met  Thr Asp Asp Lys Val  Asp Lys Thr Leu Glu  Gln Gln Glu 
    1340                 1345                 1350             


Asn Phe  Ala Glu Val Ala Arg  Ser Arg Asp Val Glu  Val Leu Glu 
    1355                 1360                 1365             


Gly Lys  Pro Ile Tyr Val Asp  Cys Phe Gly Asn Leu  Val Pro Leu 
    1370                 1375                 1380             


Thr Lys  Ser Gly Gln His His  Ile Phe Ser Phe Phe  Ala Phe Lys 
    1385                 1390                 1395             


Glu Asn  Arg Leu Pro Leu Phe  Val Lys Val Arg Asp  Thr Thr Gln 
    1400                 1405                 1410             


Glu Pro  Cys Gly Arg Leu Ser  Phe Met Lys Glu Pro  Lys Ser Thr 
    1415                 1420                 1425             


Arg Gly  Leu Val His Gln Ala  Ile Cys Asn Leu Asn  Ile Thr Leu 
    1430                 1435                 1440             


Pro Ile  Tyr Thr Lys Glu Ser  Glu Ser Asp Gln Glu  Gln Glu Glu 
    1445                 1450                 1455             


Glu Ile  Asp Met Thr Ser Glu  Lys Asn Pro Gln Asp  Glu Gln Glu 
    1460                 1465                 1470             


Arg Ile  Glu Glu Arg Leu Ala  Tyr Ile Ala Asp His  Leu Gly Phe 
    1475                 1480                 1485             


Ser Trp  Thr Glu Leu Ala Arg  Glu Leu Asp Phe Thr  Glu Glu Gln 
    1490                 1495                 1500             


Ile His  Gln Ile Arg Ile Glu  Asn Pro Asn Ser Leu  Gln Asp Gln 
    1505                 1510                 1515             


Ser His  Ala Leu Leu Lys Tyr  Trp Leu Glu Arg Asp  Gly Lys His 
    1520                 1525                 1530             


Ala Thr  Asp Thr Asn Leu Val  Glu Cys Leu Thr Lys  Ile Asn Arg 
    1535                 1540                 1545             


Met Asp  Ile Val His Leu Met  Glu Thr Asn Thr Glu  Pro Leu Gln 
    1550                 1555                 1560             


Glu Arg  Ile Ser His Ser Tyr  Ala Glu Ile Glu Gln  Thr Ile Thr 
    1565                 1570                 1575             


Leu Asp  His Ser Glu Gly Phe  Ser Val Leu Gln Glu  Glu Leu Cys 
    1580                 1585                 1590             


Thr Ala  Gln His Lys Gln Lys  Glu Glu Gln Ala Val  Ser Lys Glu 
    1595                 1600                 1605             


Ser Glu  Thr Cys Asp His Pro  Pro Ile Val Ser Glu  Glu Asp Ile 
    1610                 1615                 1620             


Ser Val  Gly Tyr Ser Thr Phe  Gln Asp Gly Val Pro  Lys Thr Glu 
    1625                 1630                 1635             


Gly Asp  Ser Ser Ala Thr Ala  Leu Phe Pro Gln Thr  His Lys Glu 
    1640                 1645                 1650             


Gln Val  Gln Gln Asp Phe Ser  Gly Lys Met Gln Asp  Leu Pro Glu 
    1655                 1660                 1665             


Glu Ser  Ser Leu Glu Tyr Gln  Gln Glu Tyr Phe Val  Thr Thr Pro 
    1670                 1675                 1680             


Gly Thr  Glu Thr Ser Glu Thr  Gln Lys Ala Met Ile  Val Pro Ser 
    1685                 1690                 1695             


Ser Pro  Ser Lys Thr Pro Glu  Glu Val Ser Thr Pro  Ala Glu Glu 
    1700                 1705                 1710             


Glu Lys  Leu Tyr Leu Gln Thr  Pro Thr Ser Ser Glu  Arg Gly Gly 
    1715                 1720                 1725             


Ser Pro  Ile Ile Gln Glu Pro  Glu Glu Pro Ser Glu  His Arg Glu 
    1730                 1735                 1740             


Glu Ser  Ser Pro Arg Lys Thr  Ser Leu Val Ile Val  Glu Ser Ala 
    1745                 1750                 1755             


Asp Asn  Gln Pro Glu Thr Cys  Glu Arg Leu Asp Glu  Asp Ala Ala 
    1760                 1765                 1770             


Phe Glu  Lys Gly Asp Asp Met  Pro Glu Ile Pro Pro  Glu Thr Val 
    1775                 1780                 1785             


Thr Glu  Glu Glu Tyr Ile Asp  Glu His Gly His Thr  Val Val Lys 
    1790                 1795                 1800             


Lys Val  Thr Arg Lys Ile Ile  Arg Arg Tyr Val Ser  Ser Glu Gly 
    1805                 1810                 1815             


Thr Glu  Lys Glu Glu Ile Met  Val Gln Gly Met Pro  Gln Glu Pro 
    1820                 1825                 1830             


Val Asn  Ile Glu Glu Gly Asp  Gly Tyr Ser Lys Val  Ile Lys Arg 
    1835                 1840                 1845             


Val Val  Leu Lys Ser Asp Thr  Glu Gln Ser Glu Asp  Asn Asn Glu 
    1850                 1855                 1860             


<210>  3063
<211>  271
<212>  PRT
<213>  homo sapiens

<400>  3063

Met Tyr Tyr Ala Val Ser Gln Ala Arg Val Asn Ala Val Pro Gly Thr 
1               5                   10                  15      


Met Leu Arg Pro Gln Arg Pro Gly Asp Leu Gln Leu Gly Ala Ser Leu 
            20                  25                  30          


Tyr Glu Leu Val Gly Tyr Arg Gln Pro Pro Ser Ser Ser Ser Ser Ser 
        35                  40                  45              


Thr Ser Ser Thr Ser Ser Thr Ser Ser Ser Ser Thr Thr Ala Pro Leu 
    50                  55                  60                  


Leu Pro Lys Ala Ala Arg Glu Lys Pro Glu Ala Pro Ala Glu Pro Pro 
65                  70                  75                  80  


Gly Pro Gly Pro Gly Ser Gly Ala His Pro Gly Gly Ser Ala Arg Pro 
                85                  90                  95      


Asp Ala Lys Glu Glu Gln Gln Gln Gln Leu Arg Arg Lys Ile Asn Ser 
            100                 105                 110         


Arg Glu Arg Lys Arg Met Gln Asp Leu Asn Leu Ala Met Asp Ala Leu 
        115                 120                 125             


Arg Glu Val Ile Leu Pro Tyr Ser Ala Ala His Cys Gln Gly Ala Pro 
    130                 135                 140                 


Gly Arg Lys Leu Ser Lys Ile Ala Thr Leu Leu Leu Ala Arg Asn Tyr 
145                 150                 155                 160 


Ile Leu Leu Leu Gly Ser Ser Leu Gln Glu Leu Arg Arg Ala Leu Gly 
                165                 170                 175     


Glu Gly Ala Gly Pro Ala Ala Pro Arg Leu Leu Leu Ala Gly Leu Pro 
            180                 185                 190         


Leu Leu Ala Ala Ala Pro Gly Ser Val Leu Leu Ala Pro Gly Ala Val 
        195                 200                 205             


Gly Pro Pro Asp Ala Leu Arg Pro Ala Lys Tyr Leu Ser Leu Ala Leu 
    210                 215                 220                 


Asp Glu Pro Pro Cys Gly Gln Phe Ala Leu Pro Gly Gly Gly Ala Gly 
225                 230                 235                 240 


Gly Pro Gly Leu Cys Thr Cys Ala Val Cys Lys Phe Pro His Leu Val 
                245                 250                 255     


Pro Ala Ser Leu Gly Leu Ala Ala Val Gln Ala Gln Phe Ser Lys 
            260                 265                 270     


<210>  3064
<211>  731
<212>  PRT
<213>  homo sapiens

<400>  3064

Met Val Val Glu His Pro Glu Phe Leu Lys Ala Gly Lys Glu Pro Gly 
1               5                   10                  15      


Leu Gln Ile Trp Arg Val Glu Lys Phe Asp Leu Val Pro Val Pro Thr 
            20                  25                  30          


Asn Leu Tyr Gly Asp Phe Phe Thr Gly Asp Ala Tyr Val Ile Leu Lys 
        35                  40                  45              


Thr Val Gln Leu Arg Asn Gly Asn Leu Gln Tyr Asp Leu His Tyr Trp 
    50                  55                  60                  


Leu Gly Asn Glu Cys Ser Gln Asp Glu Ser Gly Ala Ala Ala Ile Phe 
65                  70                  75                  80  


Thr Val Gln Leu Asp Asp Tyr Leu Asn Gly Arg Ala Val Gln His Arg 
                85                  90                  95      


Glu Val Gln Gly Phe Glu Ser Ala Thr Phe Leu Gly Tyr Phe Lys Ser 
            100                 105                 110         


Gly Leu Lys Tyr Lys Lys Gly Gly Val Ala Ser Gly Phe Lys His Val 
        115                 120                 125             


Val Pro Asn Glu Val Val Val Gln Arg Leu Phe Gln Val Lys Gly Arg 
    130                 135                 140                 


Arg Val Val Arg Ala Thr Glu Val Pro Val Ser Trp Glu Ser Phe Asn 
145                 150                 155                 160 


Asn Gly Asp Cys Phe Ile Leu Asp Leu Gly Asn Asn Ile His Gln Trp 
                165                 170                 175     


Cys Gly Ser Asn Ser Asn Arg Tyr Glu Arg Leu Lys Ala Thr Gln Val 
            180                 185                 190         


Ser Lys Gly Ile Arg Asp Asn Glu Arg Ser Gly Arg Ala Arg Val His 
        195                 200                 205             


Val Ser Glu Glu Gly Thr Glu Pro Glu Ala Met Leu Gln Val Leu Gly 
    210                 215                 220                 


Pro Lys Pro Ala Leu Pro Ala Gly Thr Glu Asp Thr Ala Lys Glu Asp 
225                 230                 235                 240 


Ala Ala Asn Arg Lys Leu Ala Lys Leu Tyr Lys Val Ser Asn Gly Ala 
                245                 250                 255     


Gly Thr Met Ser Val Ser Leu Val Ala Asp Glu Asn Pro Phe Ala Gln 
            260                 265                 270         


Gly Ala Leu Lys Ser Glu Asp Cys Phe Ile Leu Asp His Gly Lys Asp 
        275                 280                 285             


Gly Lys Ile Phe Val Trp Lys Gly Lys Gln Ala Asn Thr Glu Glu Arg 
    290                 295                 300                 


Lys Ala Ala Leu Lys Thr Ala Ser Asp Phe Ile Thr Lys Met Asp Tyr 
305                 310                 315                 320 


Pro Lys Gln Thr Gln Val Ser Val Leu Pro Glu Gly Gly Glu Thr Pro 
                325                 330                 335     


Leu Phe Lys Gln Phe Phe Lys Asn Trp Arg Asp Pro Asp Gln Thr Asp 
            340                 345                 350         


Gly Leu Gly Leu Ser Tyr Leu Ser Ser His Ile Ala Asn Val Glu Arg 
        355                 360                 365             


Val Pro Phe Asp Ala Ala Thr Leu His Thr Ser Thr Ala Met Ala Ala 
    370                 375                 380                 


Gln His Gly Met Asp Asp Asp Gly Thr Gly Gln Lys Gln Ile Trp Arg 
385                 390                 395                 400 


Ile Glu Gly Ser Asn Lys Val Pro Val Asp Pro Ala Thr Tyr Gly Gln 
                405                 410                 415     


Phe Tyr Gly Gly Asp Ser Tyr Ile Ile Leu Tyr Asn Tyr Arg His Gly 
            420                 425                 430         


Gly Arg Gln Gly Gln Ile Ile Tyr Asn Trp Gln Gly Ala Gln Ser Thr 
        435                 440                 445             


Gln Asp Glu Val Ala Ala Ser Ala Ile Leu Thr Ala Gln Leu Asp Glu 
    450                 455                 460                 


Glu Leu Gly Gly Thr Pro Val Gln Ser Arg Val Val Gln Gly Lys Glu 
465                 470                 475                 480 


Pro Ala His Leu Met Ser Leu Phe Gly Gly Lys Pro Met Ile Ile Tyr 
                485                 490                 495     


Lys Gly Gly Thr Ser Arg Glu Gly Gly Gln Thr Ala Pro Ala Ser Thr 
            500                 505                 510         


Arg Leu Phe Gln Val Arg Ala Asn Ser Ala Gly Ala Thr Arg Ala Val 
        515                 520                 525             


Glu Val Leu Pro Lys Ala Gly Ala Leu Asn Ser Asn Asp Ala Phe Val 
    530                 535                 540                 


Leu Lys Thr Pro Ser Ala Ala Tyr Leu Trp Val Gly Thr Gly Ala Ser 
545                 550                 555                 560 


Glu Ala Glu Lys Thr Gly Ala Gln Glu Leu Leu Arg Val Leu Arg Ala 
                565                 570                 575     


Gln Pro Val Gln Val Ala Glu Gly Ser Glu Pro Asp Gly Phe Trp Glu 
            580                 585                 590         


Ala Leu Gly Gly Lys Ala Ala Tyr Arg Thr Ser Pro Arg Leu Lys Asp 
        595                 600                 605             


Lys Lys Met Asp Ala His Pro Pro Arg Leu Phe Ala Cys Ser Asn Lys 
    610                 615                 620                 


Ile Gly Arg Phe Val Ile Glu Glu Val Pro Gly Glu Leu Met Gln Glu 
625                 630                 635                 640 


Asp Leu Ala Thr Asp Asp Val Met Leu Leu Asp Thr Trp Asp Gln Val 
                645                 650                 655     


Phe Val Trp Val Gly Lys Asp Ser Gln Glu Glu Glu Lys Thr Glu Ala 
            660                 665                 670         


Leu Thr Ser Ala Lys Arg Tyr Ile Glu Thr Asp Pro Ala Asn Arg Asp 
        675                 680                 685             


Arg Arg Thr Pro Ile Thr Val Val Lys Gln Gly Phe Glu Pro Pro Ser 
    690                 695                 700                 


Phe Val Gly Trp Phe Leu Gly Trp Asp Asp Asp Tyr Trp Ser Val Asp 
705                 710                 715                 720 


Pro Leu Asp Arg Ala Met Ala Glu Leu Ala Ala 
                725                 730     


<210>  3065
<211>  1883
<212>  PRT
<213>  homo sapiens

<400>  3065

Met Gly Lys Arg Ala Gly Gly Gly Ala Thr Gly Ala Thr Thr Ala Ala 
1               5                   10                  15      


Val Ser Thr Ser Ala Gly Ala Gly Leu Glu Pro Ala Ala Ala Arg Ser 
            20                  25                  30          


Gly Gly Pro Arg Ser Ala Ala Ala Gly Leu Leu Gly Ala Leu His Leu 
        35                  40                  45              


Val Met Thr Leu Val Val Ala Ala Ala Arg Ala Glu Lys Glu Ala Phe 
    50                  55                  60                  


Val Gln Ser Glu Ser Ile Ile Glu Val Leu Arg Phe Asp Asp Gly Gly 
65                  70                  75                  80  


Leu Leu Gln Thr Glu Thr Thr Leu Gly Leu Ser Ser Tyr Gln Gln Lys 
                85                  90                  95      


Ser Ile Ser Leu Tyr Arg Gly Asn Cys Arg Pro Ile Arg Phe Glu Pro 
            100                 105                 110         


Pro Met Leu Asp Phe His Glu Gln Pro Val Gly Met Pro Lys Met Glu 
        115                 120                 125             


Lys Val Tyr Leu His Asn Pro Ser Ser Glu Glu Thr Ile Thr Leu Val 
    130                 135                 140                 


Ser Ile Ser Ala Thr Thr Ser His Phe His Ala Ser Phe Phe Gln Asn 
145                 150                 155                 160 


Arg Lys Ile Leu Pro Gly Gly Asn Thr Ser Phe Asp Val Val Phe Leu 
                165                 170                 175     


Ala Arg Val Val Gly Asn Val Glu Asn Thr Leu Phe Ile Asn Thr Ser 
            180                 185                 190         


Asn His Gly Val Phe Thr Tyr Gln Val Phe Gly Val Gly Val Pro Asn 
        195                 200                 205             


Pro Tyr Arg Leu Arg Pro Phe Leu Gly Ala Arg Val Pro Val Asn Ser 
    210                 215                 220                 


Ser Phe Ser Pro Ile Ile Asn Ile His Asn Pro His Ser Glu Pro Leu 
225                 230                 235                 240 


Gln Val Val Glu Met Tyr Ser Ser Gly Gly Asp Leu His Leu Glu Leu 
                245                 250                 255     


Pro Thr Gly Gln Gln Gly Gly Thr Arg Lys Leu Trp Glu Ile Pro Pro 
            260                 265                 270         


Tyr Glu Thr Lys Gly Val Met Arg Ala Ser Phe Ser Ser Arg Glu Ala 
        275                 280                 285             


Asp Asn His Thr Ala Phe Ile Arg Ile Lys Thr Asn Ala Ser Asp Ser 
    290                 295                 300                 


Thr Glu Phe Ile Ile Leu Pro Val Glu Val Glu Val Thr Thr Ala Pro 
305                 310                 315                 320 


Gly Ile Tyr Ser Ser Thr Glu Met Leu Asp Phe Gly Thr Leu Arg Thr 
                325                 330                 335     


Gln Asp Leu Pro Lys Val Leu Asn Leu His Leu Leu Asn Ser Gly Thr 
            340                 345                 350         


Lys Asp Val Pro Ile Thr Ser Val Arg Pro Thr Pro Gln Asn Asp Ala 
        355                 360                 365             


Ile Thr Val His Phe Lys Pro Ile Thr Leu Lys Ala Ser Glu Ser Lys 
    370                 375                 380                 


Tyr Thr Lys Val Ala Ser Ile Ser Phe Asp Ala Ser Lys Ala Lys Lys 
385                 390                 395                 400 


Pro Ser Gln Phe Ser Gly Lys Ile Thr Val Lys Ala Lys Glu Lys Ser 
                405                 410                 415     


Tyr Ser Lys Leu Glu Ile Pro Tyr Gln Ala Glu Val Leu Asp Gly Tyr 
            420                 425                 430         


Leu Gly Phe Asp His Ala Ala Thr Leu Phe His Ile Arg Asp Ser Pro 
        435                 440                 445             


Ala Asp Pro Val Glu Arg Pro Ile Tyr Leu Thr Asn Thr Phe Ser Phe 
    450                 455                 460                 


Ala Ile Leu Ile His Asp Val Leu Leu Pro Glu Glu Ala Lys Thr Met 
465                 470                 475                 480 


Phe Lys Val His Asn Phe Ser Lys Pro Val Leu Ile Leu Pro Asn Glu 
                485                 490                 495     


Ser Gly Tyr Ile Phe Thr Leu Leu Phe Met Pro Ser Thr Ser Ser Met 
            500                 505                 510         


His Ile Asp Asn Asn Ile Leu Leu Ile Thr Asn Ala Ser Lys Phe His 
        515                 520                 525             


Leu Pro Val Arg Val Tyr Thr Gly Phe Leu Asp Tyr Phe Val Leu Pro 
    530                 535                 540                 


Pro Lys Ile Glu Glu Arg Phe Ile Asp Phe Gly Val Leu Ser Ala Thr 
545                 550                 555                 560 


Glu Ala Ser Asn Ile Leu Phe Ala Ile Ile Asn Ser Asn Pro Ile Glu 
                565                 570                 575     


Leu Ala Ile Lys Ser Trp His Ile Ile Gly Asp Gly Leu Ser Ile Glu 
            580                 585                 590         


Leu Val Ala Val Glu Arg Gly Asn Arg Thr Thr Ile Ile Ser Ser Leu 
        595                 600                 605             


Pro Glu Phe Glu Lys Ser Ser Leu Ser Asp Gln Ser Ser Val Thr Leu 
    610                 615                 620                 


Ala Ser Gly Tyr Phe Ala Val Phe Arg Val Lys Leu Thr Ala Lys Lys 
625                 630                 635                 640 


Leu Glu Gly Ile His Asp Gly Ala Ile Gln Ile Thr Thr Asp Tyr Glu 
                645                 650                 655     


Ile Leu Thr Ile Pro Val Lys Ala Val Ile Ala Val Gly Ser Leu Thr 
            660                 665                 670         


Cys Phe Pro Lys His Val Val Leu Pro Pro Ser Phe Pro Gly Lys Ile 
        675                 680                 685             


Val His Gln Ser Leu Asn Ile Met Asn Ser Phe Ser Gln Lys Val Lys 
    690                 695                 700                 


Ile Gln Gln Ile Arg Ser Leu Ser Glu Asp Val Arg Phe Tyr Tyr Lys 
705                 710                 715                 720 


Arg Leu Arg Gly Asn Lys Glu Asp Leu Glu Pro Gly Lys Lys Ser Lys 
                725                 730                 735     


Ile Ala Asn Ile Tyr Phe Asp Pro Gly Leu Gln Cys Gly Asp His Cys 
            740                 745                 750         


Tyr Val Gly Leu Pro Phe Leu Ser Lys Ser Glu Pro Lys Val Gln Pro 
        755                 760                 765             


Gly Val Ala Met Gln Glu Asp Met Trp Asp Ala Asp Trp Asp Leu His 
    770                 775                 780                 


Gln Ser Leu Phe Lys Gly Trp Thr Gly Ile Lys Glu Asn Ser Gly His 
785                 790                 795                 800 


Arg Leu Ser Ala Ile Phe Glu Val Asn Thr Asp Leu Gln Lys Asn Ile 
                805                 810                 815     


Ile Ser Lys Ile Thr Ala Glu Leu Ser Trp Pro Ser Ile Leu Ser Ser 
            820                 825                 830         


Pro Arg His Leu Lys Phe Pro Leu Thr Asn Thr Asn Cys Ser Ser Glu 
        835                 840                 845             


Glu Glu Ile Thr Leu Glu Asn Pro Ala Asp Val Pro Val Tyr Val Gln 
    850                 855                 860                 


Phe Ile Pro Leu Ala Leu Tyr Ser Asn Pro Ser Val Phe Val Asp Lys 
865                 870                 875                 880 


Leu Val Ser Arg Phe Asn Leu Ser Lys Val Ala Lys Ile Asp Leu Arg 
                885                 890                 895     


Thr Leu Glu Phe Gln Val Phe Arg Asn Ser Ala His Pro Leu Gln Ser 
            900                 905                 910         


Ser Thr Gly Phe Met Glu Gly Leu Ser Arg His Leu Ile Leu Asn Leu 
        915                 920                 925             


Ile Leu Lys Pro Gly Glu Lys Lys Ser Val Lys Val Lys Phe Thr Pro 
    930                 935                 940                 


Val His Asn Arg Thr Val Ser Ser Leu Ile Ile Val Arg Asn Asn Leu 
945                 950                 955                 960 


Thr Val Met Asp Ala Val Met Val Gln Gly Gln Gly Thr Thr Glu Asn 
                965                 970                 975     


Leu Arg Val Ala Gly Lys Leu Pro Gly Pro Gly Ser Ser Leu Arg Phe 
            980                 985                 990         


Lys Ile Thr Glu Ala Leu Leu Lys  Asp Cys Thr Asp Ser  Leu Lys Leu 
        995                 1000                 1005             


Arg Glu  Pro Asn Phe Thr Leu  Lys Arg Thr Phe Lys  Val Glu Asn 
    1010                 1015                 1020             


Thr Gly  Gln Leu Gln Ile His  Ile Glu Thr Ile Glu  Ile Ser Gly 
    1025                 1030                 1035             


Tyr Ser  Cys Glu Gly Tyr Gly  Phe Lys Val Val Asn  Cys Gln Glu 
    1040                 1045                 1050             


Phe Thr  Leu Ser Ala Asn Ala  Ser Arg Asp Ile Ile  Ile Leu Phe 
    1055                 1060                 1065             


Thr Pro  Asp Phe Thr Ala Ser  Arg Val Ile Arg Glu  Leu Lys Phe 
    1070                 1075                 1080             


Ile Thr  Thr Ser Gly Ser Glu  Phe Val Phe Ile Leu  Asn Ala Ser 
    1085                 1090                 1095             


Leu Pro  Tyr His Met Leu Ala  Thr Cys Ala Glu Ala  Leu Pro Arg 
    1100                 1105                 1110             


Pro Asn  Trp Glu Leu Ala Leu  Tyr Ile Ile Ile Ser  Gly Ile Met 
    1115                 1120                 1125             


Ser Ala  Leu Phe Leu Leu Val  Ile Gly Thr Ala Tyr  Leu Glu Ala 
    1130                 1135                 1140             


Gln Gly  Ile Trp Glu Pro Phe  Arg Arg Arg Leu Ser  Phe Glu Ala 
    1145                 1150                 1155             


Ser Asn  Pro Pro Phe Asp Val  Gly Arg Pro Phe Asp  Leu Arg Arg 
    1160                 1165                 1170             


Ile Val  Gly Ile Ser Ser Glu  Gly Asn Leu Asn Thr  Leu Ser Cys 
    1175                 1180                 1185             


Asp Pro  Gly His Ser Arg Gly  Phe Cys Gly Ala Gly  Gly Ser Ser 
    1190                 1195                 1200             


Ser Arg  Pro Ser Ala Gly Ser  His Lys Gln Cys Gly  Pro Ser Val 
    1205                 1210                 1215             


His Pro  His Ser Ser His Ser  Asn Arg Asn Ser Ala  Asp Val Glu 
    1220                 1225                 1230             


Asn Val  Arg Ala Lys Asn Ser  Ser Ser Thr Ser Ser  Arg Thr Ser 
    1235                 1240                 1245             


Ala Gln  Ala Ala Ser Ser Gln  Ser Ala Asn Lys Thr  Ser Pro Leu 
    1250                 1255                 1260             


Val Leu  Asp Ser Asn Thr Val  Thr Gln Gly His Thr  Ala Gly Arg 
    1265                 1270                 1275             


Lys Ser  Lys Gly Ala Lys Gln  Ser Gln His Gly Ser  Gln His His 
    1280                 1285                 1290             


Ala His  Ser Pro Leu Glu Gln  His Pro Gln Pro Pro  Leu Pro Pro 
    1295                 1300                 1305             


Pro Val  Pro Gln Pro Gln Glu  Pro Gln Pro Glu Arg  Leu Ser Pro 
    1310                 1315                 1320             


Ala Pro  Leu Ala His Pro Ser  His Pro Glu Arg Ala  Ser Ser Ala 
    1325                 1330                 1335             


Arg His  Ser Ser Glu Asp Ser  Asp Ile Thr Ser Leu  Ile Glu Ala 
    1340                 1345                 1350             


Met Asp  Lys Asp Phe Asp His  His Asp Ser Pro Ala  Leu Glu Val 
    1355                 1360                 1365             


Phe Thr  Glu Gln Pro Pro Ser  Pro Leu Pro Lys Ser  Lys Gly Lys 
    1370                 1375                 1380             


Gly Lys  Pro Leu Gln Arg Lys  Val Lys Pro Pro Lys  Lys Gln Glu 
    1385                 1390                 1395             


Glu Lys  Glu Lys Lys Gly Lys  Gly Lys Pro Gln Glu  Asp Glu Leu 
    1400                 1405                 1410             


Lys Asp  Ser Leu Ala Asp Asp  Asp Ser Ser Ser Thr  Thr Thr Glu 
    1415                 1420                 1425             


Thr Ser  Asn Pro Asp Thr Glu  Pro Leu Leu Lys Glu  Asp Thr Glu 
    1430                 1435                 1440             


Lys Gln  Lys Gly Lys Gln Ala  Met Pro Glu Lys His  Glu Ser Glu 
    1445                 1450                 1455             


Met Ser  Gln Val Lys Gln Lys  Ser Lys Lys Leu Leu  Asn Ile Lys 
    1460                 1465                 1470             


Lys Glu  Ile Pro Thr Asp Val  Lys Pro Ser Ser Leu  Glu Leu Pro 
    1475                 1480                 1485             


Tyr Thr  Pro Pro Leu Glu Ser  Lys Gln Arg Arg Asn  Leu Pro Ser 
    1490                 1495                 1500             


Lys Ile  Pro Leu Pro Thr Ala  Met Thr Ser Gly Ser  Lys Ser Arg 
    1505                 1510                 1515             


Asn Ala  Gln Lys Thr Lys Gly  Thr Ser Lys Leu Val  Asp Asn Arg 
    1520                 1525                 1530             


Pro Pro  Ala Leu Ala Lys Phe  Leu Pro Asn Ser Gln  Glu Leu Gly 
    1535                 1540                 1545             


Asn Thr  Ser Ser Ser Glu Gly  Glu Lys Asp Ser Pro  Pro Pro Glu 
    1550                 1555                 1560             


Trp Asp  Ser Val Pro Val His  Lys Pro Gly Ser Ser  Thr Asp Ser 
    1565                 1570                 1575             


Leu Tyr  Lys Leu Ser Leu Gln  Thr Leu Asn Ala Asp  Ile Phe Leu 
    1580                 1585                 1590             


Lys Gln  Arg Gln Thr Ser Pro  Thr Pro Ala Ser Pro  Ser Pro Pro 
    1595                 1600                 1605             


Ala Ala  Pro Cys Pro Phe Val  Ala Arg Gly Ser Tyr  Ser Ser Ile 
    1610                 1615                 1620             


Val Asn  Ser Ser Ser Ser Ser  Asp Pro Lys Ile Lys  Gln Pro Asn 
    1625                 1630                 1635             


Gly Ser  Lys His Lys Leu Thr  Lys Ala Ala Ser Leu  Pro Gly Lys 
    1640                 1645                 1650             


Asn Gly  Asn Pro Thr Phe Ala  Ala Val Thr Ala Gly  Tyr Asp Lys 
    1655                 1660                 1665             


Ser Pro  Gly Gly Asn Gly Phe  Ala Lys Val Ser Ser  Asn Lys Thr 
    1670                 1675                 1680             


Gly Phe  Ser Ser Ser Leu Gly  Ile Ser His Ala Pro  Val Asp Ser 
    1685                 1690                 1695             


Asp Gly  Ser Asp Ser Ser Gly  Leu Trp Ser Pro Val  Ser Asn Pro 
    1700                 1705                 1710             


Ser Ser  Pro Asp Phe Thr Pro  Leu Asn Ser Phe Ser  Ala Phe Gly 
    1715                 1720                 1725             


Asn Ser  Phe Asn Leu Thr Gly  Glu Val Phe Ser Lys  Leu Gly Leu 
    1730                 1735                 1740             


Ser Arg  Ser Cys Asn Gln Ala  Ser Gln Arg Ser Trp  Asn Glu Phe 
    1745                 1750                 1755             


Asn Ser  Gly Pro Ser Tyr Leu  Trp Glu Ser Pro Ala  Thr Asp Pro 
    1760                 1765                 1770             


Ser Pro  Ser Trp Pro Ala Ser  Ser Gly Ser Pro Thr  His Thr Ala 
    1775                 1780                 1785             


Thr Ser  Val Leu Gly Asn Thr  Ser Gly Leu Trp Ser  Thr Thr Pro 
    1790                 1795                 1800             


Phe Ser  Ser Ser Ile Trp Ser  Ser Asn Leu Ser Ser  Ala Leu Pro 
    1805                 1810                 1815             


Phe Thr  Thr Pro Ala Asn Thr  Leu Ala Ser Ile Gly  Leu Met Gly 
    1820                 1825                 1830             


Thr Glu  Asn Ser Pro Ala Pro  His Ala Pro Ser Thr  Ser Ser Pro 
    1835                 1840                 1845             


Ala Asp  Asp Leu Gly Gln Thr  Tyr Asn Pro Trp Arg  Ile Trp Ser 
    1850                 1855                 1860             


Pro Thr  Ile Gly Arg Arg Ser  Ser Asp Pro Trp Ser  Asn Ser His 
    1865                 1870                 1875             


Phe Pro  His Glu Asn 
    1880             


<210>  3066
<211>  479
<212>  PRT
<213>  homo sapiens

<400>  3066

Met Glu Lys Gly Leu Thr Leu Pro Gln Asp Cys Arg Asp Phe Val His 
1               5                   10                  15      


Ser Leu Lys Met Arg Ser Lys Tyr Ala Leu Phe Leu Val Phe Val Val 
            20                  25                  30          


Ile Val Phe Val Phe Ile Glu Lys Glu Asn Lys Ile Ile Ser Arg Val 
        35                  40                  45              


Ser Asp Lys Leu Lys Gln Ile Pro Gln Ala Leu Ala Asp Ala Asn Ser 
    50                  55                  60                  


Thr Asp Pro Ala Leu Ile Leu Ala Glu Asn Ala Ser Leu Leu Ser Leu 
65                  70                  75                  80  


Ser Glu Leu Asp Ser Ala Phe Ser Gln Leu Gln Ser Arg Leu Arg Asn 
                85                  90                  95      


Leu Ser Leu Gln Leu Gly Val Glu Pro Ala Met Glu Ala Ala Gly Glu 
            100                 105                 110         


Glu Glu Glu Glu Gln Arg Lys Glu Glu Glu Pro Pro Arg Pro Ala Val 
        115                 120                 125             


Ala Gly Pro Arg Arg His Val Leu Leu Met Ala Thr Thr Arg Thr Gly 
    130                 135                 140                 


Ser Ser Phe Val Gly Glu Phe Phe Asn Gln Gln Gly Asn Ile Phe Tyr 
145                 150                 155                 160 


Leu Phe Glu Pro Leu Trp His Ile Glu Arg Thr Val Ser Phe Glu Pro 
                165                 170                 175     


Gly Gly Ala Asn Ala Ala Gly Ser Ala Leu Val Tyr Arg Asp Val Leu 
            180                 185                 190         


Lys Gln Leu Phe Leu Cys Asp Leu Tyr Val Leu Glu His Phe Ile Thr 
        195                 200                 205             


Pro Leu Pro Glu Asp His Leu Thr Gln Phe Met Phe Arg Arg Gly Ser 
    210                 215                 220                 


Ser Arg Ser Leu Cys Glu Asp Pro Val Cys Thr Pro Phe Val Lys Lys 
225                 230                 235                 240 


Val Phe Glu Lys Tyr His Cys Lys Asn Arg Arg Cys Gly Pro Leu Asn 
                245                 250                 255     


Val Thr Leu Ala Ala Glu Ala Cys Arg Arg Lys Glu His Met Ala Leu 
            260                 265                 270         


Lys Ala Val Arg Ile Arg Gln Leu Glu Phe Leu Gln Pro Leu Ala Glu 
        275                 280                 285             


Asp Pro Arg Leu Asp Leu Arg Val Ile Gln Leu Val Arg Asp Pro Arg 
    290                 295                 300                 


Ala Val Leu Ala Ser Arg Met Val Ala Phe Ala Gly Lys Tyr Lys Thr 
305                 310                 315                 320 


Trp Lys Lys Trp Leu Asp Asp Glu Gly Gln Asp Gly Leu Arg Glu Glu 
                325                 330                 335     


Glu Val Gln Arg Leu Arg Gly Asn Cys Glu Ser Ile Arg Leu Ser Ala 
            340                 345                 350         


Glu Leu Gly Leu Arg Gln Pro Ala Trp Leu Arg Gly Arg Tyr Met Leu 
        355                 360                 365             


Val Arg Tyr Glu Asp Val Ala Arg Gly Pro Leu Gln Lys Ala Arg Glu 
    370                 375                 380                 


Met Tyr Arg Phe Ala Gly Ile Pro Leu Thr Pro Gln Val Glu Asp Trp 
385                 390                 395                 400 


Ile Gln Lys Asn Thr Gln Ala Ala His Asp Gly Ser Gly Ile Tyr Ser 
                405                 410                 415     


Thr Gln Lys Asn Ser Ser Glu Gln Phe Glu Lys Trp Arg Phe Ser Met 
            420                 425                 430         


Pro Phe Lys Leu Ala Gln Val Val Gln Ala Ala Cys Gly Pro Ala Met 
        435                 440                 445             


Arg Leu Phe Gly Tyr Lys Leu Ala Arg Asp Ala Ala Ala Leu Thr Asn 
    450                 455                 460                 


Arg Ser Val Ser Leu Leu Glu Glu Arg Gly Thr Phe Trp Val Thr 
465                 470                 475                 


<210>  3067
<211>  164
<212>  PRT
<213>  homo sapiens

<400>  3067

Met Ser Val Asp Pro Leu Ser Ser Lys Ala Leu Lys Ile Lys Arg Glu 
1               5                   10                  15      


Leu Ser Glu Asn Thr Pro His Leu Ser Asp Glu Ala Leu Met Gly Leu 
            20                  25                  30          


Ser Val Arg Glu Leu Asn Arg His Leu Arg Gly Leu Ser Ala Glu Glu 
        35                  40                  45              


Val Thr Arg Leu Lys Gln Arg Arg Arg Thr Leu Lys Asn Arg Gly Tyr 
    50                  55                  60                  


Ala Ala Ser Cys Arg Val Lys Arg Val Cys Gln Lys Glu Glu Leu Gln 
65                  70                  75                  80  


Lys Gln Lys Ser Glu Leu Glu Arg Glu Val Asp Lys Leu Ala Arg Glu 
                85                  90                  95      


Asn Ala Ala Met Arg Leu Glu Leu Asp Ala Leu Arg Gly Lys Cys Glu 
            100                 105                 110         


Ala Leu Gln Gly Phe Ala Arg Ser Val Ala Ala Ala Arg Gly Pro Ala 
        115                 120                 125             


Thr Leu Val Ala Pro Ala Ser Val Ile Thr Ile Val Lys Ser Thr Pro 
    130                 135                 140                 


Gly Ser Gly Ser Gly Pro Ala His Gly Pro Asp Pro Ala His Gly Pro 
145                 150                 155                 160 


Ala Ser Cys Ser 
                


<210>  3068
<211>  993
<212>  PRT
<213>  homo sapiens

<400>  3068

Met Gly Ser Gly Arg Val Pro Gly Leu Cys Leu Leu Val Leu Leu Val 
1               5                   10                  15      


His Ala Arg Ala Ala Gln Tyr Ser Lys Ala Ala Gln Asp Val Asp Glu 
            20                  25                  30          


Cys Val Glu Gly Thr Asp Asn Cys His Ile Asp Ala Ile Cys Gln Asn 
        35                  40                  45              


Thr Pro Arg Ser Tyr Lys Cys Ile Cys Lys Ser Gly Tyr Thr Gly Asp 
    50                  55                  60                  


Gly Lys His Cys Lys Asp Val Asp Glu Cys Glu Arg Glu Asp Asn Ala 
65                  70                  75                  80  


Gly Cys Val His Asp Cys Val Asn Ile Pro Gly Asn Tyr Arg Cys Thr 
                85                  90                  95      


Cys Tyr Asp Gly Phe His Leu Ala His Asp Gly His Asn Cys Leu Asp 
            100                 105                 110         


Val Asp Glu Cys Ala Glu Gly Asn Gly Gly Cys Gln Gln Ser Cys Val 
        115                 120                 125             


Asn Met Met Gly Ser Tyr Glu Cys His Cys Arg Glu Gly Phe Phe Leu 
    130                 135                 140                 


Ser Asp Asn Gln His Thr Cys Ile Gln Arg Pro Glu Glu Gly Met Asn 
145                 150                 155                 160 


Cys Met Asn Lys Asn His Gly Cys Ala His Ile Cys Arg Glu Thr Pro 
                165                 170                 175     


Lys Gly Gly Ile Ala Cys Glu Cys Arg Pro Gly Phe Glu Leu Thr Lys 
            180                 185                 190         


Asn Gln Arg Asp Cys Lys Leu Thr Cys Asn Tyr Gly Asn Gly Gly Cys 
        195                 200                 205             


Gln His Thr Cys Asp Asp Thr Glu Gln Gly Pro Arg Cys Gly Cys His 
    210                 215                 220                 


Ile Lys Phe Val Leu His Thr Asp Gly Lys Thr Cys Ile Glu Thr Cys 
225                 230                 235                 240 


Ala Val Asn Asn Gly Gly Cys Asp Ser Lys Cys His Asp Ala Ala Thr 
                245                 250                 255     


Gly Val His Cys Thr Cys Pro Val Gly Phe Met Leu Gln Pro Asp Arg 
            260                 265                 270         


Lys Thr Cys Lys Asp Ile Asp Glu Cys Arg Leu Asn Asn Gly Gly Cys 
        275                 280                 285             


Asp His Ile Cys Arg Asn Thr Val Gly Ser Phe Glu Cys Ser Cys Lys 
    290                 295                 300                 


Lys Gly Tyr Lys Leu Leu Ile Asn Glu Arg Asn Cys Gln Asp Ile Asp 
305                 310                 315                 320 


Glu Cys Ser Phe Asp Arg Thr Cys Asp His Ile Cys Val Asn Thr Pro 
                325                 330                 335     


Gly Ser Phe Gln Cys Leu Cys His Arg Gly Tyr Leu Leu Tyr Gly Ile 
            340                 345                 350         


Thr His Cys Gly Asp Val Asp Glu Cys Ser Ile Asn Arg Gly Gly Cys 
        355                 360                 365             


Arg Phe Gly Cys Ile Asn Thr Pro Gly Ser Tyr Gln Cys Thr Cys Pro 
    370                 375                 380                 


Ala Gly Gln Gly Arg Leu His Trp Asn Gly Lys Asp Cys Thr Glu Pro 
385                 390                 395                 400 


Leu Lys Cys Gln Gly Ser Pro Gly Ala Ser Lys Ala Met Leu Ser Cys 
                405                 410                 415     


Asn Arg Ser Gly Lys Lys Asp Thr Cys Ala Leu Thr Cys Pro Ser Arg 
            420                 425                 430         


Ala Arg Phe Leu Pro Glu Ser Glu Asn Gly Phe Thr Val Ser Cys Gly 
        435                 440                 445             


Thr Pro Ser Pro Arg Ala Ala Pro Ala Arg Ala Gly His Asn Gly Asn 
    450                 455                 460                 


Ser Thr Asn Ser Asn His Cys His Glu Ala Ala Val Leu Ser Ile Lys 
465                 470                 475                 480 


Gln Arg Ala Ser Phe Lys Ile Lys Asp Ala Lys Cys Arg Leu His Leu 
                485                 490                 495     


Arg Asn Lys Gly Lys Thr Glu Glu Ala Gly Arg Ile Thr Gly Pro Gly 
            500                 505                 510         


Gly Ala Pro Cys Ser Glu Cys Gln Val Thr Phe Ile His Leu Lys Cys 
        515                 520                 525             


Asp Ser Ser Arg Lys Gly Lys Gly Arg Arg Ala Arg Thr Pro Pro Gly 
    530                 535                 540                 


Lys Glu Val Thr Arg Leu Thr Leu Glu Leu Glu Ala Glu Val Arg Ala 
545                 550                 555                 560 


Glu Glu Thr Thr Ala Ser Cys Gly Leu Pro Cys Leu Arg Gln Arg Met 
                565                 570                 575     


Glu Arg Arg Leu Lys Gly Ser Leu Lys Met Leu Arg Lys Ser Ile Asn 
            580                 585                 590         


Gln Asp Arg Phe Leu Leu Arg Leu Ala Gly Leu Asp Tyr Glu Leu Ala 
        595                 600                 605             


His Lys Pro Gly Leu Val Ala Gly Glu Arg Ala Glu Pro Met Glu Ser 
    610                 615                 620                 


Cys Arg Pro Gly Gln His Arg Ala Gly Thr Lys Cys Val Ser Cys Pro 
625                 630                 635                 640 


Gln Gly Thr Tyr Tyr His Gly Gln Thr Glu Gln Cys Val Pro Cys Pro 
                645                 650                 655     


Ala Gly Thr Phe Gln Glu Arg Glu Gly Gln Leu Ser Cys Asp Leu Cys 
            660                 665                 670         


Pro Gly Ser Asp Ala His Gly Pro Leu Gly Ala Thr Asn Val Thr Thr 
        675                 680                 685             


Cys Ala Gly Gln Cys Pro Pro Gly Gln His Ser Val Asp Gly Phe Lys 
    690                 695                 700                 


Pro Cys Gln Pro Cys Pro Arg Gly Thr Tyr Gln Pro Glu Ala Gly Arg 
705                 710                 715                 720 


Thr Leu Cys Phe Pro Cys Gly Gly Gly Leu Thr Thr Lys His Glu Gly 
                725                 730                 735     


Ala Ile Ser Phe Gln Asp Cys Asp Thr Lys Val Gln Cys Ser Pro Gly 
            740                 745                 750         


His Tyr Tyr Asn Thr Ser Ile His Arg Cys Ile Arg Cys Ala Met Gly 
        755                 760                 765             


Ser Tyr Gln Pro Asp Phe Arg Gln Asn Phe Cys Ser Arg Cys Pro Gly 
    770                 775                 780                 


Asn Thr Ser Thr Asp Phe Asp Gly Ser Thr Ser Val Ala Gln Cys Lys 
785                 790                 795                 800 


Asn Arg Gln Cys Gly Gly Glu Leu Gly Glu Phe Thr Gly Tyr Ile Glu 
                805                 810                 815     


Ser Pro Asn Tyr Pro Gly Asn Tyr Pro Ala Gly Val Glu Cys Ile Trp 
            820                 825                 830         


Asn Ile Asn Pro Pro Pro Lys Arg Lys Ile Leu Ile Val Val Pro Glu 
        835                 840                 845             


Ile Phe Leu Pro Ser Glu Asp Glu Cys Gly Asp Val Leu Val Met Arg 
    850                 855                 860                 


Lys Asn Ser Ser Pro Ser Ser Ile Thr Thr Tyr Glu Thr Cys Gln Thr 
865                 870                 875                 880 


Tyr Glu Arg Pro Ile Ala Phe Thr Ala Arg Ser Arg Lys Leu Trp Ile 
                885                 890                 895     


Asn Phe Lys Thr Ser Glu Ala Asn Ser Ala Arg Gly Phe Gln Ile Pro 
            900                 905                 910         


Tyr Val Thr Tyr Asp Glu Asp Tyr Glu Gln Leu Val Glu Asp Ile Val 
        915                 920                 925             


Arg Asp Gly Arg Leu Tyr Ala Ser Glu Asn His Gln Glu Ile Leu Lys 
    930                 935                 940                 


Asp Lys Lys Leu Ile Lys Ala Phe Phe Glu Val Leu Ala His Pro Gln 
945                 950                 955                 960 


Asn Tyr Phe Lys Tyr Thr Glu Lys His Lys Glu Met Leu Pro Lys Ser 
                965                 970                 975     


Phe Ile Lys Leu Leu Arg Ser Lys Val Ser Ser Phe Leu Arg Pro Tyr 
            980                 985                 990         


Lys 
    


<210>  3069
<211>  1233
<212>  PRT
<213>  homo sapiens

<400>  3069

Met Ser Ala Pro Ala Gly Ser Ser His Pro Ala Ala Ser Ala Arg Ile 
1               5                   10                  15      


Pro Pro Lys Phe Gly Gly Ala Ala Val Ser Gly Ala Ala Ala Pro Ala 
            20                  25                  30          


Gly Pro Gly Ala Gly Pro Ala Pro His Gln Gln Asn Gly Pro Ala Gln 
        35                  40                  45              


Asn Gln Met Gln Val Pro Ser Gly Tyr Gly Leu His His Gln Asn Tyr 
    50                  55                  60                  


Ile Ala Pro Ser Gly His Tyr Ser Gln Gly Pro Gly Lys Met Thr Ser 
65                  70                  75                  80  


Leu Pro Leu Asp Thr Gln Cys Gly Asp Tyr Tyr Ser Ala Leu Tyr Thr 
                85                  90                  95      


Val Pro Thr Gln Asn Val Thr Pro Asn Thr Val Asn Gln Gln Pro Gly 
            100                 105                 110         


Ala Gln Gln Leu Tyr Ser Arg Gly Pro Pro Ala Pro His Ile Val Gly 
        115                 120                 125             


Ser Thr Leu Gly Ser Phe Gln Gly Ala Ala Ser Ser Ala Ser His Leu 
    130                 135                 140                 


His Thr Ser Ala Ser Gln Pro Tyr Ser Ser Phe Val Asn His Tyr Asn 
145                 150                 155                 160 


Ser Pro Ala Met Tyr Ser Ala Ser Ser Ser Val Ala Ser Gln Gly Phe 
                165                 170                 175     


Pro Ser Thr Cys Gly His Tyr Ala Met Ser Thr Val Ser Asn Ala Ala 
            180                 185                 190         


Tyr Pro Ser Val Ser Tyr Pro Ser Leu Pro Ala Gly Asp Thr Tyr Gly 
        195                 200                 205             


Gln Met Phe Thr Ser Gln Asn Ala Pro Thr Val Arg Pro Val Lys Asp 
    210                 215                 220                 


Asn Ser Phe Ser Gly Gln Asn Thr Ala Ile Ser His Pro Ser Pro Leu 
225                 230                 235                 240 


Pro Pro Leu Pro Ser Gln Gln His His Gln Gln Gln Ser Leu Ser Gly 
                245                 250                 255     


Tyr Ser Thr Leu Thr Trp Ser Ser Pro Gly Leu Pro Ser Thr Gln Asp 
            260                 265                 270         


Asn Leu Ile Arg Asn His Thr Gly Ser Leu Ala Val Ala Asn Asn Asn 
        275                 280                 285             


Pro Thr Ile Thr Val Ala Asp Ser Leu Ser Cys Pro Val Met Gln Asn 
    290                 295                 300                 


Val Gln Pro Pro Lys Ser Ser Pro Val Val Ser Thr Val Leu Ser Gly 
305                 310                 315                 320 


Ser Ser Gly Ser Ser Ser Thr Arg Thr Pro Pro Thr Ala Asn His Pro 
                325                 330                 335     


Val Glu Pro Val Thr Ser Val Thr Gln Pro Ser Glu Leu Leu Gln Gln 
            340                 345                 350         


Lys Gly Val Asp Ser Ser Ser Thr Thr Ser Ser Ala Ser Pro Met Pro 
        355                 360                 365             


Asn Ser Tyr Asp Ala Leu Glu Gly Gly Ser Tyr Pro Asp Met Leu Ser 
    370                 375                 380                 


Ser Ser Ala Ser Ser Pro Ala Pro Asp Pro Ala Pro Glu Pro Asp Pro 
385                 390                 395                 400 


Ala Ser Ala Pro Ala Pro Ala Ser Ala Pro Ala Pro Val Val Pro Gln 
                405                 410                 415     


Pro Ser Lys Met Ala Lys Pro Phe Gly Tyr Gly Tyr Pro Thr Leu Gln 
            420                 425                 430         


Pro Gly Tyr Gln Asn Ala Thr Ala Pro Leu Ile Ser Gly Val Gln Pro 
        435                 440                 445             


Ser Asn Pro Val Tyr Ser Gly Phe Gln Gln Tyr Pro Gln Gln Tyr Pro 
    450                 455                 460                 


Gly Val Asn Gln Leu Ser Ser Ser Ile Gly Gly Leu Ser Leu Gln Ser 
465                 470                 475                 480 


Ser Pro Gln Pro Glu Ser Leu Arg Pro Val Asn Leu Thr Gln Glu Arg 
                485                 490                 495     


Asn Ile Leu Pro Met Thr Pro Val Trp Ala Pro Val Pro Asn Leu Asn 
            500                 505                 510         


Ala Asp Leu Lys Lys Leu Asn Cys Ser Pro Asp Ser Phe Arg Cys Thr 
        515                 520                 525             


Leu Thr Asn Ile Pro Gln Thr Gln Ala Leu Leu Asn Lys Ala Lys Leu 
    530                 535                 540                 


Pro Leu Gly Leu Leu Leu His Pro Phe Arg Asp Leu Thr Gln Leu Pro 
545                 550                 555                 560 


Val Ile Thr Ser Asn Thr Ile Val Arg Cys Arg Ser Cys Arg Thr Tyr 
                565                 570                 575     


Ile Asn Pro Phe Val Ser Phe Ile Asp Gln Arg Arg Trp Lys Cys Asn 
            580                 585                 590         


Leu Cys Tyr Arg Val Asn Asp Val Pro Glu Glu Phe Met Tyr Asn Pro 
        595                 600                 605             


Leu Thr Arg Ser Tyr Gly Glu Pro His Lys Arg Pro Glu Val Gln Asn 
    610                 615                 620                 


Ser Thr Val Glu Phe Ile Ala Ser Ser Asp Tyr Met Leu Arg Pro Pro 
625                 630                 635                 640 


Gln Pro Ala Val Tyr Leu Phe Val Leu Asp Val Ser His Asn Ala Val 
                645                 650                 655     


Glu Ala Gly Tyr Leu Thr Ile Leu Cys Gln Ser Leu Leu Glu Asn Leu 
            660                 665                 670         


Asp Lys Leu Pro Gly Asp Ser Arg Thr Arg Ile Gly Phe Met Thr Phe 
        675                 680                 685             


Asp Ser Thr Ile His Phe Tyr Asn Leu Gln Glu Gly Leu Ser Gln Pro 
    690                 695                 700                 


Gln Met Leu Ile Val Ser Asp Ile Asp Asp Val Phe Leu Pro Thr Pro 
705                 710                 715                 720 


Asp Ser Leu Leu Val Asn Leu Tyr Glu Ser Lys Glu Leu Ile Lys Asp 
                725                 730                 735     


Leu Leu Asn Ala Leu Pro Asn Met Phe Thr Asn Thr Arg Glu Thr His 
            740                 745                 750         


Ser Ala Leu Gly Pro Ala Leu Gln Ala Ala Phe Lys Leu Met Ser Pro 
        755                 760                 765             


Thr Gly Gly Arg Val Ser Val Phe Gln Thr Gln Leu Pro Ser Leu Gly 
    770                 775                 780                 


Ala Gly Leu Leu Gln Ser Arg Glu Asp Pro Asn Gln Arg Ser Ser Thr 
785                 790                 795                 800 


Lys Val Val Gln His Leu Gly Pro Ala Thr Asp Phe Tyr Lys Lys Leu 
                805                 810                 815     


Ala Leu Asp Cys Ser Gly Gln Gln Thr Ala Val Asp Leu Phe Leu Leu 
            820                 825                 830         


Ser Ser Gln Tyr Ser Asp Leu Ala Ser Leu Ala Cys Met Ser Lys Tyr 
        835                 840                 845             


Ser Ala Gly Cys Ile Tyr Tyr Tyr Pro Ser Phe His Tyr Thr His Asn 
    850                 855                 860                 


Pro Ser Gln Ala Glu Lys Leu Gln Lys Asp Leu Lys Arg Tyr Leu Thr 
865                 870                 875                 880 


Arg Lys Ile Gly Phe Glu Ala Val Met Arg Ile Arg Cys Thr Lys Gly 
                885                 890                 895     


Leu Ser Met His Thr Phe His Gly Asn Phe Phe Val Arg Ser Thr Asp 
            900                 905                 910         


Leu Leu Ser Leu Ala Asn Ile Asn Pro Asp Ala Gly Phe Ala Val Gln 
        915                 920                 925             


Leu Ser Ile Glu Glu Ser Leu Thr Asp Thr Ser Leu Val Cys Phe Gln 
    930                 935                 940                 


Thr Ala Leu Leu Tyr Thr Ser Ser Lys Gly Glu Arg Arg Ile Arg Val 
945                 950                 955                 960 


His Thr Leu Cys Leu Pro Val Val Ser Ser Leu Ala Asp Val Tyr Ala 
                965                 970                 975     


Gly Val Asp Val Gln Ala Ala Ile Cys Leu Leu Ala Asn Met Ala Val 
            980                 985                 990         


Asp Arg Ser Val Ser Ser Ser Leu  Ser Asp Ala Arg Asp  Ala Leu Val 
        995                 1000                 1005             


Asn Ala  Val Val Asp Ser Leu  Ser Ala Tyr Gly Ser  Thr Val Ser 
    1010                 1015                 1020             


Asn Leu  Gln His Ser Ala Leu  Met Ala Pro Ser Ser  Leu Lys Leu 
    1025                 1030                 1035             


Phe Pro  Leu Tyr Val Leu Ala  Leu Leu Lys Gln Lys  Ala Phe Arg 
    1040                 1045                 1050             


Thr Gly  Thr Ser Thr Arg Leu  Asp Asp Arg Val Tyr  Ala Met Cys 
    1055                 1060                 1065             


Gln Ile  Lys Ser Gln Pro Leu  Val His Leu Met Lys  Met Ile His 
    1070                 1075                 1080             


Pro Asn  Leu Tyr Arg Ile Asp  Arg Leu Thr Asp Glu  Gly Ala Val 
    1085                 1090                 1095             


His Val  Asn Asp Arg Ile Val  Pro Gln Pro Pro Leu  Gln Lys Leu 
    1100                 1105                 1110             


Ser Ala  Glu Lys Leu Thr Arg  Glu Gly Ala Phe Leu  Met Asp Cys 
    1115                 1120                 1125             


Gly Ser  Val Phe Tyr Ile Trp  Val Gly Lys Gly Cys  Asp Asn Asn 
    1130                 1135                 1140             


Phe Ile  Glu Asp Val Leu Gly  Tyr Thr Asn Phe Ala  Ser Ile Pro 
    1145                 1150                 1155             


Gln Lys  Met Thr His Leu Pro  Glu Leu Asp Thr Leu  Ser Ser Glu 
    1160                 1165                 1170             


Arg Ala  Arg Ser Phe Ile Thr  Trp Leu Arg Asp Ser  Arg Pro Leu 
    1175                 1180                 1185             


Ser Pro  Ile Leu His Ile Val  Lys Asp Glu Ser Pro  Ala Lys Ala 
    1190                 1195                 1200             


Glu Phe  Phe Gln His Leu Ile  Glu Asp Arg Thr Glu  Ala Ala Phe 
    1205                 1210                 1215             


Ser Tyr  Tyr Glu Phe Leu Leu  His Val Gln Gln Gln  Ile Cys Lys 
    1220                 1225                 1230             


<210>  3070
<211>  1951
<212>  PRT
<213>  homo sapiens

<400>  3070

Met Ala Gln Ala Leu Leu Val Pro Pro Gly Pro Glu Ser Phe Arg Leu 
1               5                   10                  15      


Phe Thr Arg Glu Ser Leu Ala Ala Ile Glu Lys Arg Ala Ala Glu Glu 
            20                  25                  30          


Lys Ala Lys Lys Pro Lys Lys Glu Gln Asp Asn Asp Asp Glu Asn Lys 
        35                  40                  45              


Pro Lys Pro Asn Ser Asp Leu Glu Ala Gly Lys Asn Leu Pro Phe Ile 
    50                  55                  60                  


Tyr Gly Asp Ile Pro Pro Glu Met Val Ser Glu Pro Leu Glu Asp Leu 
65                  70                  75                  80  


Asp Pro Tyr Tyr Ile Asn Lys Lys Thr Phe Ile Val Met Asn Lys Gly 
                85                  90                  95      


Lys Ala Ile Phe Arg Phe Ser Ala Thr Ser Ala Leu Tyr Ile Leu Thr 
            100                 105                 110         


Pro Leu Asn Pro Val Arg Lys Ile Ala Ile Lys Ile Leu Val His Ser 
        115                 120                 125             


Leu Phe Ser Met Leu Ile Met Cys Thr Ile Leu Thr Asn Cys Val Phe 
    130                 135                 140                 


Met Thr Leu Ser Asn Pro Pro Asp Trp Thr Lys Asn Val Glu Tyr Thr 
145                 150                 155                 160 


Phe Thr Gly Ile Tyr Thr Phe Glu Ser Leu Ile Lys Ile Leu Ala Arg 
                165                 170                 175     


Gly Phe Cys Leu Glu Asp Phe Thr Phe Leu Arg Asp Pro Trp Asn Trp 
            180                 185                 190         


Leu Asp Phe Ser Val Ile Val Met Ala Tyr Val Thr Glu Phe Val Ser 
        195                 200                 205             


Leu Gly Asn Val Ser Ala Leu Arg Thr Phe Arg Val Leu Arg Ala Leu 
    210                 215                 220                 


Lys Thr Ile Ser Val Ile Pro Gly Leu Lys Thr Ile Val Gly Ala Leu 
225                 230                 235                 240 


Ile Gln Ser Val Lys Lys Leu Ser Asp Val Met Ile Leu Thr Val Phe 
                245                 250                 255     


Cys Leu Ser Val Phe Ala Leu Ile Gly Leu Gln Leu Phe Met Gly Asn 
            260                 265                 270         


Leu Arg Asn Lys Cys Leu Gln Trp Pro Pro Ser Asp Ser Ala Phe Glu 
        275                 280                 285             


Thr Asn Thr Thr Ser Tyr Phe Asn Gly Thr Met Asp Ser Asn Gly Thr 
    290                 295                 300                 


Phe Val Asn Val Thr Met Ser Thr Phe Asn Trp Lys Asp Tyr Ile Gly 
305                 310                 315                 320 


Asp Asp Ser His Phe Tyr Val Leu Asp Gly Gln Lys Asp Pro Leu Leu 
                325                 330                 335     


Cys Gly Asn Gly Ser Asp Ala Gly Gln Cys Pro Glu Gly Tyr Ile Cys 
            340                 345                 350         


Val Lys Ala Gly Arg Asn Pro Asn Tyr Gly Tyr Thr Ser Phe Asp Thr 
        355                 360                 365             


Phe Ser Trp Ala Phe Leu Ser Leu Phe Arg Leu Met Thr Gln Asp Tyr 
    370                 375                 380                 


Trp Glu Asn Leu Tyr Gln Leu Thr Leu Arg Ala Ala Gly Lys Thr Tyr 
385                 390                 395                 400 


Met Ile Phe Phe Val Leu Val Ile Phe Leu Gly Ser Phe Tyr Leu Val 
                405                 410                 415     


Asn Leu Ile Leu Ala Val Val Ala Met Ala Tyr Glu Glu Gln Asn Gln 
            420                 425                 430         


Ala Thr Leu Glu Glu Ala Glu Gln Lys Glu Ala Glu Phe Gln Gln Met 
        435                 440                 445             


Leu Glu Gln Leu Lys Lys Gln Gln Glu Glu Ala Gln Ala Val Ala Ala 
    450                 455                 460                 


Ala Ser Ala Ala Ser Arg Asp Phe Ser Gly Ile Gly Gly Leu Gly Glu 
465                 470                 475                 480 


Leu Leu Glu Ser Ser Ser Glu Ala Ser Lys Leu Ser Ser Lys Ser Ala 
                485                 490                 495     


Lys Glu Trp Arg Asn Arg Arg Lys Lys Arg Arg Gln Arg Glu His Leu 
            500                 505                 510         


Glu Gly Asn Asn Lys Gly Glu Arg Asp Ser Phe Pro Lys Ser Glu Ser 
        515                 520                 525             


Glu Asp Ser Val Lys Arg Ser Ser Phe Leu Phe Ser Met Asp Gly Asn 
    530                 535                 540                 


Arg Leu Thr Ser Asp Lys Lys Phe Cys Ser Pro His Gln Ser Leu Leu 
545                 550                 555                 560 


Ser Ile Arg Gly Ser Leu Phe Ser Pro Arg Arg Asn Ser Lys Thr Ser 
                565                 570                 575     


Ile Phe Ser Phe Arg Gly Arg Ala Lys Asp Val Gly Ser Glu Asn Asp 
            580                 585                 590         


Phe Ala Asp Asp Glu His Ser Thr Phe Glu Asp Ser Glu Ser Arg Arg 
        595                 600                 605             


Asp Ser Leu Phe Val Pro His Arg His Gly Glu Arg Arg Asn Ser Asn 
    610                 615                 620                 


Gly Thr Thr Thr Glu Thr Glu Val Arg Lys Arg Arg Leu Ser Ser Tyr 
625                 630                 635                 640 


Gln Ile Ser Met Glu Met Leu Glu Asp Ser Ser Gly Arg Gln Arg Ala 
                645                 650                 655     


Val Ser Ile Ala Ser Ile Leu Thr Asn Thr Met Glu Glu Leu Glu Glu 
            660                 665                 670         


Ser Arg Gln Lys Cys Pro Pro Cys Trp Tyr Arg Phe Ala Asn Val Phe 
        675                 680                 685             


Leu Ile Trp Asp Cys Cys Asp Ala Trp Leu Lys Val Lys His Leu Val 
    690                 695                 700                 


Asn Leu Ile Val Met Asp Pro Phe Val Asp Leu Ala Ile Thr Ile Cys 
705                 710                 715                 720 


Ile Val Leu Asn Thr Leu Phe Met Ala Met Glu His Tyr Pro Met Thr 
                725                 730                 735     


Glu Gln Phe Ser Ser Val Leu Thr Val Gly Asn Leu Val Phe Thr Gly 
            740                 745                 750         


Ile Phe Thr Ala Glu Met Val Leu Lys Ile Ile Ala Met Asp Pro Tyr 
        755                 760                 765             


Tyr Tyr Phe Gln Glu Gly Trp Asn Ile Phe Asp Gly Ile Ile Val Ser 
    770                 775                 780                 


Leu Ser Leu Met Glu Leu Gly Leu Ser Asn Val Glu Gly Leu Ser Val 
785                 790                 795                 800 


Leu Arg Ser Phe Arg Leu Leu Arg Val Phe Lys Leu Ala Lys Ser Trp 
                805                 810                 815     


Pro Thr Leu Asn Met Leu Ile Lys Ile Ile Gly Asn Ser Val Gly Ala 
            820                 825                 830         


Leu Gly Asn Leu Thr Leu Val Leu Ala Ile Ile Val Phe Ile Phe Ala 
        835                 840                 845             


Val Val Gly Met Gln Leu Phe Gly Lys Ser Tyr Lys Glu Cys Val Cys 
    850                 855                 860                 


Lys Ile Asn Asp Asp Cys Thr Leu Pro Arg Trp His Met Asn Asp Phe 
865                 870                 875                 880 


Phe His Ser Phe Leu Ile Val Phe Arg Val Leu Cys Gly Glu Trp Ile 
                885                 890                 895     


Glu Thr Met Trp Asp Cys Met Glu Val Ala Gly Gln Thr Met Cys Leu 
            900                 905                 910         


Ile Val Phe Met Leu Val Met Val Ile Gly Asn Leu Val Val Leu Asn 
        915                 920                 925             


Leu Phe Leu Ala Leu Leu Leu Ser Ser Phe Ser Ser Asp Asn Leu Ala 
    930                 935                 940                 


Ala Thr Asp Asp Asp Asn Glu Met Asn Asn Leu Gln Ile Ala Val Gly 
945                 950                 955                 960 


Arg Met Gln Lys Gly Ile Asp Tyr Val Lys Asn Lys Met Arg Glu Cys 
                965                 970                 975     


Phe Gln Lys Ala Phe Phe Arg Lys Pro Lys Val Ile Glu Ile His Glu 
            980                 985                 990         


Gly Asn Lys Ile Asp Ser Cys Met  Ser Asn Asn Thr Gly  Ile Glu Ile 
        995                 1000                 1005             


Ser Lys  Glu Leu Asn Tyr Leu  Arg Asp Gly Asn Gly  Thr Thr Ser 
    1010                 1015                 1020             


Gly Val  Gly Thr Gly Ser Ser  Val Glu Lys Tyr Val  Ile Asp Glu 
    1025                 1030                 1035             


Asn Asp  Tyr Met Ser Phe Ile  Asn Asn Pro Ser Leu  Thr Val Thr 
    1040                 1045                 1050             


Val Pro  Ile Ala Val Gly Glu  Ser Asp Phe Glu Asn  Leu Asn Thr 
    1055                 1060                 1065             


Glu Glu  Phe Ser Ser Glu Ser  Glu Leu Glu Glu Ser  Lys Glu Lys 
    1070                 1075                 1080             


Leu Asn  Ala Thr Ser Ser Ser  Glu Gly Ser Thr Val  Asp Val Val 
    1085                 1090                 1095             


Leu Pro  Arg Glu Gly Glu Gln  Ala Glu Thr Glu Pro  Glu Glu Asp 
    1100                 1105                 1110             


Leu Lys  Pro Glu Ala Cys Phe  Thr Glu Gly Cys Ile  Lys Lys Phe 
    1115                 1120                 1125             


Pro Phe  Cys Gln Val Ser Thr  Glu Glu Gly Lys Gly  Lys Ile Trp 
    1130                 1135                 1140             


Trp Asn  Leu Arg Lys Thr Cys  Tyr Ser Ile Val Glu  His Asn Trp 
    1145                 1150                 1155             


Phe Glu  Thr Phe Ile Val Phe  Met Ile Leu Leu Ser  Ser Gly Ala 
    1160                 1165                 1170             


Leu Ala  Phe Glu Asp Ile Tyr  Ile Glu Gln Arg Lys  Thr Ile Lys 
    1175                 1180                 1185             


Thr Met  Leu Glu Tyr Ala Asp  Lys Val Phe Thr Tyr  Ile Phe Ile 
    1190                 1195                 1200             


Leu Glu  Met Leu Leu Lys Trp  Val Ala Tyr Gly Phe  Gln Thr Tyr 
    1205                 1210                 1215             


Phe Thr  Asn Ala Trp Cys Trp  Leu Asp Phe Leu Ile  Val Asp Val 
    1220                 1225                 1230             


Ser Leu  Val Ser Leu Val Ala  Asn Ala Leu Gly Tyr  Ser Glu Leu 
    1235                 1240                 1245             


Gly Ala  Ile Lys Ser Leu Arg  Thr Leu Arg Ala Leu  Arg Pro Leu 
    1250                 1255                 1260             


Arg Ala  Leu Ser Arg Phe Glu  Gly Met Arg Val Val  Val Asn Ala 
    1265                 1270                 1275             


Leu Val  Gly Ala Ile Pro Ser  Ile Met Asn Val Leu  Leu Val Cys 
    1280                 1285                 1290             


Leu Ile  Phe Trp Leu Ile Phe  Ser Ile Met Gly Val  Asn Leu Phe 
    1295                 1300                 1305             


Ala Gly  Lys Phe Tyr His Cys  Val Asn Met Thr Thr  Gly Asn Met 
    1310                 1315                 1320             


Phe Asp  Ile Ser Asp Val Asn  Asn Leu Ser Asp Cys  Gln Ala Leu 
    1325                 1330                 1335             


Gly Lys  Gln Ala Arg Trp Lys  Asn Val Lys Val Asn  Phe Asp Asn 
    1340                 1345                 1350             


Val Gly  Ala Gly Tyr Leu Ala  Leu Leu Gln Val Ala  Thr Phe Lys 
    1355                 1360                 1365             


Gly Trp  Met Asp Ile Met Tyr  Ala Ala Val Asp Ser  Arg Asp Val 
    1370                 1375                 1380             


Lys Leu  Gln Pro Val Tyr Glu  Glu Asn Leu Tyr Met  Tyr Leu Tyr 
    1385                 1390                 1395             


Phe Val  Ile Phe Ile Ile Phe  Gly Ser Phe Phe Thr  Leu Asn Leu 
    1400                 1405                 1410             


Phe Ile  Gly Val Ile Ile Asp  Asn Phe Asn Gln Gln  Lys Lys Lys 
    1415                 1420                 1425             


Phe Gly  Gly Gln Asp Ile Phe  Met Thr Glu Glu Gln  Lys Lys Tyr 
    1430                 1435                 1440             


Tyr Asn  Ala Met Lys Lys Leu  Gly Ser Lys Lys Pro  Gln Lys Pro 
    1445                 1450                 1455             


Ile Pro  Arg Pro Ala Asn Lys  Phe Gln Gly Met Val  Phe Asp Phe 
    1460                 1465                 1470             


Val Thr  Arg Gln Val Phe Asp  Ile Ser Ile Met Ile  Leu Ile Cys 
    1475                 1480                 1485             


Leu Asn  Met Val Thr Met Met  Val Glu Thr Asp Asp  Gln Gly Lys 
    1490                 1495                 1500             


Tyr Met  Thr Leu Val Leu Ser  Arg Ile Asn Leu Val  Phe Ile Val 
    1505                 1510                 1515             


Leu Phe  Thr Gly Glu Phe Val  Leu Lys Leu Val Ser  Leu Arg His 
    1520                 1525                 1530             


Tyr Tyr  Phe Thr Ile Gly Trp  Asn Ile Phe Asp Phe  Val Val Val 
    1535                 1540                 1545             


Ile Leu  Ser Ile Val Gly Met  Phe Leu Ala Glu Met  Ile Glu Lys 
    1550                 1555                 1560             


Tyr Phe  Val Ser Pro Thr Leu  Phe Arg Val Ile Arg  Leu Ala Arg 
    1565                 1570                 1575             


Ile Gly  Arg Ile Leu Arg Leu  Ile Lys Gly Ala Lys  Gly Ile Arg 
    1580                 1585                 1590             


Thr Leu  Leu Phe Ala Leu Met  Met Ser Leu Pro Ala  Leu Phe Asn 
    1595                 1600                 1605             


Ile Gly  Leu Leu Leu Phe Leu  Val Met Phe Ile Tyr  Ala Ile Phe 
    1610                 1615                 1620             


Gly Met  Ser Asn Phe Ala Tyr  Val Lys Lys Glu Ala  Gly Ile Asp 
    1625                 1630                 1635             


Asp Met  Phe Asn Phe Glu Thr  Phe Gly Asn Ser Met  Ile Cys Leu 
    1640                 1645                 1650             


Phe Gln  Ile Thr Thr Ser Ala  Gly Trp Asp Gly Leu  Leu Ala Pro 
    1655                 1660                 1665             


Ile Leu  Asn Ser Ala Pro Pro  Asp Cys Asp Pro Asp  Thr Ile His 
    1670                 1675                 1680             


Pro Gly  Ser Ser Val Lys Gly  Asp Cys Gly Asn Pro  Ser Val Gly 
    1685                 1690                 1695             


Ile Phe  Phe Phe Val Ser Tyr  Ile Ile Ile Ser Phe  Leu Val Val 
    1700                 1705                 1710             


Val Asn  Met Tyr Ile Ala Val  Ile Leu Glu Asn Phe  Ser Val Ala 
    1715                 1720                 1725             


Thr Glu  Glu Ser Ala Glu Pro  Leu Ser Glu Asp Asp  Phe Glu Met 
    1730                 1735                 1740             


Phe Tyr  Glu Val Trp Glu Lys  Phe Asp Pro Asp Ala  Thr Gln Phe 
    1745                 1750                 1755             


Ile Glu  Phe Ser Lys Leu Ser  Asp Phe Ala Ala Ala  Leu Asp Pro 
    1760                 1765                 1770             


Pro Leu  Leu Ile Ala Lys Pro  Asn Lys Val Gln Leu  Ile Ala Met 
    1775                 1780                 1785             


Asp Leu  Pro Met Val Ser Gly  Asp Arg Ile His Cys  Leu Asp Ile 
    1790                 1795                 1800             


Leu Phe  Ala Phe Thr Lys Arg  Val Leu Gly Glu Ser  Gly Glu Met 
    1805                 1810                 1815             


Asp Ala  Leu Arg Ile Gln Met  Glu Asp Arg Phe Met  Ala Ser Asn 
    1820                 1825                 1830             


Pro Ser  Lys Val Ser Tyr Glu  Pro Ile Thr Thr Thr  Leu Lys Arg 
    1835                 1840                 1845             


Lys Gln  Glu Glu Val Ser Ala  Ala Ile Ile Gln Arg  Asn Phe Arg 
    1850                 1855                 1860             


Cys Tyr  Leu Leu Lys Gln Arg  Leu Lys Asn Ile Ser  Ser Asn Tyr 
    1865                 1870                 1875             


Asn Lys  Glu Ala Ile Lys Gly  Arg Ile Asp Leu Pro  Ile Lys Gln 
    1880                 1885                 1890             


Asp Met  Ile Ile Asp Lys Leu  Asn Gly Asn Ser Thr  Pro Glu Lys 
    1895                 1900                 1905             


Thr Asp  Gly Ser Ser Ser Thr  Thr Ser Pro Pro Ser  Tyr Asp Ser 
    1910                 1915                 1920             


Val Thr  Lys Pro Asp Lys Glu  Lys Phe Glu Lys Asp  Lys Pro Glu 
    1925                 1930                 1935             


Lys Glu  Ser Lys Gly Lys Glu  Val Arg Glu Asn Gln  Lys 
    1940                 1945                 1950     


<210>  3071
<211>  98
<212>  PRT
<213>  homo sapiens

<400>  3071

Met Lys Leu Met Val Leu Val Phe Thr Ile Gly Leu Thr Leu Leu Leu 
1               5                   10                  15      


Gly Val Gln Ala Met Pro Ala Asn Arg Leu Ser Cys Tyr Arg Lys Ile 
            20                  25                  30          


Leu Lys Asp His Asn Cys His Asn Leu Pro Glu Gly Val Ala Asp Leu 
        35                  40                  45              


Thr Gln Ile Asp Val Asn Val Gln Asp His Phe Trp Asp Gly Lys Gly 
    50                  55                  60                  


Cys Glu Met Ile Cys Tyr Cys Asn Phe Ser Glu Leu Leu Cys Cys Pro 
65                  70                  75                  80  


Lys Asp Val Phe Phe Gly Pro Lys Ile Ser Phe Val Ile Pro Cys Asn 
                85                  90                  95      


Asn Gln 
        


<210>  3072
<211>  389
<212>  PRT
<213>  homo sapiens

<400>  3072

Met Leu Ser Leu Arg Val Pro Leu Ala Pro Ile Thr Asp Pro Gln Gln 
1               5                   10                  15      


Leu Gln Leu Ser Pro Leu Lys Gly Leu Ser Leu Val Asp Lys Glu Asn 
            20                  25                  30          


Thr Pro Pro Ala Leu Ser Gly Thr Arg Val Leu Ala Ser Lys Thr Ala 
        35                  40                  45              


Arg Arg Ile Phe Gln Glu Pro Thr Glu Pro Lys Thr Lys Ala Ala Ala 
    50                  55                  60                  


Pro Gly Val Glu Asp Glu Pro Leu Leu Arg Glu Asn Pro Arg Arg Phe 
65                  70                  75                  80  


Val Ile Phe Pro Ile Glu Tyr His Asp Ile Trp Gln Met Tyr Lys Lys 
                85                  90                  95      


Ala Glu Ala Ser Phe Trp Thr Ala Glu Glu Val Asp Leu Ser Lys Asp 
            100                 105                 110         


Ile Gln His Trp Glu Ser Leu Lys Pro Glu Glu Arg Tyr Phe Ile Ser 
        115                 120                 125             


His Val Leu Ala Phe Phe Ala Ala Ser Asp Gly Ile Val Asn Glu Asn 
    130                 135                 140                 


Leu Val Glu Arg Phe Ser Gln Glu Val Gln Ile Thr Glu Ala Arg Cys 
145                 150                 155                 160 


Phe Tyr Gly Phe Gln Ile Ala Met Glu Asn Ile His Ser Glu Met Tyr 
                165                 170                 175     


Ser Leu Leu Ile Asp Thr Tyr Ile Lys Asp Pro Lys Glu Arg Glu Phe 
            180                 185                 190         


Leu Phe Asn Ala Ile Glu Thr Met Pro Cys Val Lys Lys Lys Ala Asp 
        195                 200                 205             


Trp Ala Leu Arg Trp Ile Gly Asp Lys Glu Ala Thr Tyr Gly Glu Arg 
    210                 215                 220                 


Val Val Ala Phe Ala Ala Val Glu Gly Ile Phe Phe Ser Gly Ser Phe 
225                 230                 235                 240 


Ala Ser Ile Phe Trp Leu Lys Lys Arg Gly Leu Met Pro Gly Leu Thr 
                245                 250                 255     


Phe Ser Asn Glu Leu Ile Ser Arg Asp Glu Gly Leu His Cys Asp Phe 
            260                 265                 270         


Ala Cys Leu Met Phe Lys His Leu Val His Lys Pro Ser Glu Glu Arg 
        275                 280                 285             


Val Arg Glu Ile Ile Ile Asn Ala Val Arg Ile Glu Gln Glu Phe Leu 
    290                 295                 300                 


Thr Glu Ala Leu Pro Val Lys Leu Ile Gly Met Asn Cys Thr Leu Met 
305                 310                 315                 320 


Lys Gln Tyr Ile Glu Phe Val Ala Asp Arg Leu Met Leu Glu Leu Gly 
                325                 330                 335     


Phe Ser Lys Val Phe Arg Val Glu Asn Pro Phe Asp Phe Met Glu Asn 
            340                 345                 350         


Ile Ser Leu Glu Gly Lys Thr Asn Phe Phe Glu Lys Arg Val Gly Glu 
        355                 360                 365             


Tyr Gln Arg Met Gly Val Met Ser Ser Pro Thr Glu Asn Ser Phe Thr 
    370                 375                 380                 


Leu Asp Ala Asp Phe 
385                 


<210>  3073
<211>  387
<212>  PRT
<213>  homo sapiens

<400>  3073

Met Thr Gly Lys Leu Ala Glu Lys Leu Pro Val Thr Met Ser Ser Leu 
1               5                   10                  15      


Leu Asn Gln Leu Pro Asp Asn Leu Tyr Pro Glu Glu Ile Pro Ser Ala 
            20                  25                  30          


Leu Asn Leu Phe Ser Gly Ser Ser Asp Ser Val Val His Tyr Asn Gln 
        35                  40                  45              


Met Ala Thr Glu Asn Val Met Asp Ile Gly Leu Thr Asn Glu Lys Pro 
    50                  55                  60                  


Asn Pro Glu Leu Ser Tyr Ser Gly Ser Phe Gln Pro Ala Pro Gly Asn 
65                  70                  75                  80  


Lys Thr Val Thr Tyr Leu Gly Lys Phe Ala Phe Asp Ser Pro Ser Asn 
                85                  90                  95      


Trp Cys Gln Asp Asn Ile Ile Ser Leu Met Ser Ala Gly Ile Leu Gly 
            100                 105                 110         


Val Pro Pro Ala Ser Gly Ala Leu Ser Thr Gln Thr Ser Thr Ala Ser 
        115                 120                 125             


Met Val Gln Pro Pro Gln Gly Asp Val Glu Ala Met Tyr Pro Ala Leu 
    130                 135                 140                 


Pro Pro Tyr Ser Asn Cys Gly Asp Leu Tyr Ser Glu Pro Val Ser Phe 
145                 150                 155                 160 


His Asp Pro Gln Gly Asn Pro Gly Leu Ala Tyr Ser Pro Gln Asp Tyr 
                165                 170                 175     


Gln Ser Ala Lys Pro Ala Leu Asp Ser Asn Leu Phe Pro Met Ile Pro 
            180                 185                 190         


Asp Tyr Asn Leu Tyr His His Pro Asn Asp Met Gly Ser Ile Pro Glu 
        195                 200                 205             


His Lys Pro Phe Gln Gly Met Asp Pro Ile Arg Val Asn Pro Pro Pro 
    210                 215                 220                 


Ile Thr Pro Leu Glu Thr Ile Lys Ala Phe Lys Asp Lys Gln Ile His 
225                 230                 235                 240 


Pro Gly Phe Gly Ser Leu Pro Gln Pro Pro Leu Thr Leu Lys Pro Ile 
                245                 250                 255     


Arg Pro Arg Lys Tyr Pro Asn Arg Pro Ser Lys Thr Pro Leu His Glu 
            260                 265                 270         


Arg Pro His Ala Cys Pro Ala Glu Gly Cys Asp Arg Arg Phe Ser Arg 
        275                 280                 285             


Ser Asp Glu Leu Thr Arg His Leu Arg Ile His Thr Gly His Lys Pro 
    290                 295                 300                 


Phe Gln Cys Arg Ile Cys Met Arg Ser Phe Ser Arg Ser Asp His Leu 
305                 310                 315                 320 


Thr Thr His Ile Arg Thr His Thr Gly Glu Lys Pro Phe Ala Cys Glu 
                325                 330                 335     


Phe Cys Gly Arg Lys Phe Ala Arg Ser Asp Glu Arg Lys Arg His Ala 
            340                 345                 350         


Lys Ile His Leu Lys Gln Lys Glu Lys Lys Ala Glu Lys Gly Gly Ala 
        355                 360                 365             


Pro Ser Ala Ser Ser Ala Pro Pro Val Ser Leu Ala Pro Val Val Thr 
    370                 375                 380                 


Thr Cys Ala 
385         


<210>  3074
<211>  251
<212>  PRT
<213>  homo sapiens

<400>  3074

Met Tyr Arg Val Ile Gln Val Ser Glu Gly Gln Leu Asp Gly Gln Thr 
1               5                   10                  15      


Glu Gly Thr Gly Ala Ile Ser Gly Tyr Pro Ala Thr Gln Ser Met Thr 
            20                  25                  30          


Gln Ala Val Ile Gln Gly Ala Phe Thr Ser Asp Asp Ala Val Asp Thr 
        35                  40                  45              


Glu Gly Thr Ala Ala Glu Thr His Tyr Thr Tyr Phe Pro Ser Thr Ala 
    50                  55                  60                  


Val Gly Asp Gly Ala Gly Gly Thr Thr Ser Gly Ser Thr Ala Ala Val 
65                  70                  75                  80  


Val Thr Thr Gln Gly Ser Glu Ala Leu Leu Gly Gln Ala Thr Pro Pro 
                85                  90                  95      


Gly Thr Gly Gln Phe Phe Val Met Met Ser Pro Gln Glu Val Leu Gln 
            100                 105                 110         


Gly Gly Ser Gln Arg Ser Ile Ala Pro Arg Thr His Pro Tyr Ser Pro 
        115                 120                 125             


Lys Ser Glu Ala Pro Arg Thr Thr Arg Asp Glu Lys Arg Arg Ala Gln 
    130                 135                 140                 


His Asn Glu Val Glu Arg Arg Arg Arg Asp Lys Ile Asn Asn Trp Ile 
145                 150                 155                 160 


Val Gln Leu Ser Lys Ile Ile Pro Asp Cys Ser Met Glu Ser Thr Lys 
                165                 170                 175     


Ser Gly Gln Ser Lys Gly Gly Ile Leu Ser Lys Ala Cys Asp Tyr Ile 
            180                 185                 190         


Gln Glu Leu Arg Gln Ser Asn His Arg Leu Ser Glu Glu Leu Gln Gly 
        195                 200                 205             


Leu Asp Gln Leu Gln Leu Asp Asn Asp Val Leu Arg Gln Gln Val Glu 
    210                 215                 220                 


Asp Leu Lys Asn Lys Asn Leu Leu Leu Arg Ala Gln Leu Arg His His 
225                 230                 235                 240 


Gly Leu Glu Val Val Ile Lys Asn Asp Ser Asn 
                245                 250     


<210>  3075
<211>  429
<212>  PRT
<213>  homo sapiens

<400>  3075

Met Ser Gly Val Arg Pro Pro Ile Met Asn Gly Pro Leu His Pro Arg 
1               5                   10                  15      


Pro Leu Val Ala Leu Leu Asp Gly Arg Asp Cys Thr Val Glu Met Pro 
            20                  25                  30          


Ile Leu Lys Asp Val Ala Thr Val Ala Phe Cys Asp Ala Gln Ser Thr 
        35                  40                  45              


Gln Glu Ile His Glu Lys Val Leu Asn Glu Ala Val Gly Ala Leu Met 
    50                  55                  60                  


Tyr His Thr Ile Thr Leu Thr Arg Glu Asp Leu Glu Lys Phe Lys Ala 
65                  70                  75                  80  


Leu Arg Ile Ile Val Arg Ile Gly Ser Gly Phe Asp Asn Ile Asp Ile 
                85                  90                  95      


Lys Ser Ala Gly Asp Leu Gly Ile Ala Val Cys Asn Val Pro Ala Ala 
            100                 105                 110         


Ser Val Glu Glu Thr Ala Asp Ser Thr Leu Cys His Ile Leu Asn Leu 
        115                 120                 125             


Tyr Arg Arg Ala Thr Trp Leu His Gln Ala Leu Arg Glu Gly Thr Arg 
    130                 135                 140                 


Val Gln Ser Val Glu Gln Ile Arg Glu Val Ala Ser Gly Ala Ala Arg 
145                 150                 155                 160 


Ile Arg Gly Glu Thr Leu Gly Ile Ile Gly Leu Gly Arg Val Gly Gln 
                165                 170                 175     


Ala Val Ala Leu Arg Ala Lys Ala Phe Gly Phe Asn Val Leu Phe Tyr 
            180                 185                 190         


Asp Pro Tyr Leu Ser Asp Gly Val Glu Arg Ala Leu Gly Leu Gln Arg 
        195                 200                 205             


Val Ser Thr Leu Gln Asp Leu Leu Phe His Ser Asp Cys Val Thr Leu 
    210                 215                 220                 


His Cys Gly Leu Asn Glu His Asn His His Leu Ile Asn Asp Phe Thr 
225                 230                 235                 240 


Val Lys Gln Met Arg Gln Gly Ala Phe Leu Val Asn Thr Ala Arg Gly 
                245                 250                 255     


Gly Leu Val Asp Glu Lys Ala Leu Ala Gln Ala Leu Lys Glu Gly Arg 
            260                 265                 270         


Ile Arg Gly Ala Ala Leu Asp Val His Glu Ser Glu Pro Phe Ser Phe 
        275                 280                 285             


Ser Gln Gly Pro Leu Lys Asp Ala Pro Asn Leu Ile Cys Thr Pro His 
    290                 295                 300                 


Ala Ala Trp Tyr Ser Glu Gln Ala Ser Ile Glu Met Arg Glu Glu Ala 
305                 310                 315                 320 


Ala Arg Glu Ile Arg Arg Ala Ile Thr Gly Arg Ile Pro Asp Ser Leu 
                325                 330                 335     


Lys Asn Cys Val Asn Lys Asp His Leu Thr Ala Ala Thr His Trp Ala 
            340                 345                 350         


Ser Met Asp Pro Ala Val Val His Pro Glu Leu Asn Gly Ala Ala Tyr 
        355                 360                 365             


Arg Tyr Pro Pro Gly Val Val Gly Val Ala Pro Thr Gly Ile Pro Ala 
    370                 375                 380                 


Ala Val Glu Gly Ile Val Pro Ser Ala Met Ser Leu Ser His Gly Leu 
385                 390                 395                 400 


Pro Pro Val Ala His Pro Pro His Ala Pro Ser Pro Gly Gln Thr Val 
                405                 410                 415     


Lys Pro Glu Ala Asp Arg Asp His Ala Ser Asp Gln Leu 
            420                 425                 


<210>  3076
<211>  687
<212>  PRT
<213>  homo sapiens

<400>  3076

Met Glu Arg Val Asn Asp Ala Ser Cys Gly Pro Ser Gly Cys Tyr Thr 
1               5                   10                  15      


Tyr Gln Val Ser Arg His Ser Thr Glu Met Leu His Asn Leu Asn Gln 
            20                  25                  30          


Gln Arg Lys Asn Gly Gly Arg Phe Cys Asp Val Leu Leu Arg Val Gly 
        35                  40                  45              


Asp Glu Ser Phe Pro Ala His Arg Ala Val Leu Ala Ala Cys Ser Glu 
    50                  55                  60                  


Tyr Phe Glu Ser Val Phe Ser Ala Gln Leu Gly Asp Gly Gly Ala Ala 
65                  70                  75                  80  


Asp Gly Gly Pro Ala Asp Val Gly Gly Ala Thr Ala Ala Pro Gly Gly 
                85                  90                  95      


Gly Ala Gly Gly Ser Arg Glu Leu Glu Met His Thr Ile Ser Ser Lys 
            100                 105                 110         


Val Phe Gly Asp Ile Leu Asp Phe Ala Tyr Thr Ser Arg Ile Val Val 
        115                 120                 125             


Arg Leu Glu Ser Phe Pro Glu Leu Met Thr Ala Ala Lys Phe Leu Leu 
    130                 135                 140                 


Met Arg Ser Val Ile Glu Ile Cys Gln Glu Val Ile Lys Gln Ser Asn 
145                 150                 155                 160 


Val Gln Ile Leu Val Pro Pro Ala Arg Ala Asp Ile Met Leu Phe Arg 
                165                 170                 175     


Pro Pro Gly Thr Ser Asp Leu Gly Phe Pro Leu Asp Met Thr Asn Gly 
            180                 185                 190         


Ala Ala Leu Ala Ala Asn Ser Asn Gly Ile Ala Gly Ser Met Gln Pro 
        195                 200                 205             


Glu Glu Glu Ala Ala Arg Ala Ala Gly Ala Ala Ile Ala Gly Gln Ala 
    210                 215                 220                 


Ser Leu Pro Val Leu Pro Gly Val Asp Arg Leu Pro Met Val Ala Gly 
225                 230                 235                 240 


Pro Leu Ser Pro Gln Leu Leu Thr Ser Pro Phe Pro Ser Val Ala Ser 
                245                 250                 255     


Ser Ala Pro Pro Leu Thr Gly Lys Arg Gly Arg Gly Arg Pro Arg Lys 
            260                 265                 270         


Ala Asn Leu Leu Asp Ser Met Phe Gly Ser Pro Gly Gly Leu Arg Glu 
        275                 280                 285             


Ala Gly Ile Leu Pro Cys Gly Leu Cys Gly Lys Val Phe Thr Asp Ala 
    290                 295                 300                 


Asn Arg Leu Arg Gln His Glu Ala Gln His Gly Val Thr Ser Leu Gln 
305                 310                 315                 320 


Leu Gly Tyr Ile Asp Leu Pro Pro Pro Arg Leu Gly Glu Asn Gly Leu 
                325                 330                 335     


Pro Ile Ser Glu Asp Pro Asp Gly Pro Arg Lys Arg Ser Arg Thr Arg 
            340                 345                 350         


Lys Gln Val Ala Cys Glu Ile Cys Gly Lys Ile Phe Arg Asp Val Tyr 
        355                 360                 365             


His Leu Asn Arg His Lys Leu Ser His Ser Gly Glu Lys Pro Tyr Ser 
    370                 375                 380                 


Cys Pro Val Cys Gly Leu Arg Phe Lys Arg Lys Asp Arg Met Ser Tyr 
385                 390                 395                 400 


His Val Arg Ser His Asp Gly Ser Val Gly Lys Pro Tyr Ile Cys Gln 
                405                 410                 415     


Ser Cys Gly Lys Gly Phe Ser Arg Pro Asp His Leu Asn Gly His Ile 
            420                 425                 430         


Lys Gln Val His Thr Ser Glu Arg Pro His Lys Cys Gln Thr Cys Asn 
        435                 440                 445             


Ala Ser Phe Ala Thr Arg Asp Arg Leu Arg Ser His Leu Ala Cys His 
    450                 455                 460                 


Glu Asp Lys Val Pro Cys Gln Val Cys Gly Lys Tyr Leu Arg Ala Ala 
465                 470                 475                 480 


Tyr Met Ala Asp His Leu Lys Lys His Ser Glu Gly Pro Ser Asn Phe 
                485                 490                 495     


Cys Ser Ile Cys Asn Arg Gly Phe Ser Ser Ala Ser Tyr Leu Lys Val 
            500                 505                 510         


His Val Lys Thr His His Gly Val Pro Leu Pro Gln Val Ser Arg His 
        515                 520                 525             


Gln Glu Pro Ile Leu Asn Gly Gly Ala Ala Phe His Cys Ala Arg Thr 
    530                 535                 540                 


Tyr Gly Asn Lys Glu Gly Gln Lys Cys Ser His Gln Asp Pro Ile Glu 
545                 550                 555                 560 


Ser Ser Asp Ser Tyr Gly Asp Leu Ser Asp Ala Ser Asp Leu Lys Thr 
                565                 570                 575     


Pro Glu Lys Gln Ser Ala Asn Gly Ser Phe Ser Cys Asp Met Ala Val 
            580                 585                 590         


Pro Lys Asn Lys Met Glu Ser Asp Gly Glu Lys Lys Tyr Pro Cys Pro 
        595                 600                 605             


Glu Cys Gly Ser Phe Phe Arg Ser Lys Ser Tyr Leu Asn Lys His Ile 
    610                 615                 620                 


Gln Lys Val His Val Arg Ala Leu Gly Gly Pro Leu Gly Asp Leu Gly 
625                 630                 635                 640 


Pro Ala Leu Gly Ser Pro Phe Ser Pro Gln Gln Asn Met Ser Leu Leu 
                645                 650                 655     


Glu Ser Phe Gly Phe Gln Ile Val Gln Ser Ala Phe Ala Ser Ser Leu 
            660                 665                 670         


Val Asp Pro Glu Val Asp Gln Gln Pro Met Gly Pro Glu Gly Lys 
        675                 680                 685         


<210>  3077
<211>  641
<212>  PRT
<213>  homo sapiens

<400>  3077

Met Glu Arg Val Asn Asp Ala Ser Cys Gly Pro Ser Gly Cys Tyr Thr 
1               5                   10                  15      


Tyr Gln Val Ser Arg His Ser Thr Glu Met Leu His Asn Leu Asn Gln 
            20                  25                  30          


Gln Arg Lys Asn Gly Gly Arg Phe Cys Asp Val Leu Leu Arg Val Gly 
        35                  40                  45              


Asp Glu Ser Phe Pro Ala His Arg Ala Val Leu Ala Ala Cys Ser Glu 
    50                  55                  60                  


Tyr Phe Glu Ser Val Phe Ser Ala Gln Leu Gly Asp Gly Gly Ala Ala 
65                  70                  75                  80  


Asp Gly Gly Pro Ala Asp Val Gly Gly Ala Thr Ala Ala Pro Gly Gly 
                85                  90                  95      


Gly Ala Gly Gly Ser Arg Glu Leu Glu Met His Thr Ile Ser Ser Lys 
            100                 105                 110         


Val Phe Gly Asp Ile Leu Asp Phe Ala Tyr Thr Ser Arg Ile Val Val 
        115                 120                 125             


Arg Leu Glu Ser Phe Pro Glu Leu Met Thr Ala Ala Lys Phe Leu Leu 
    130                 135                 140                 


Met Arg Ser Val Ile Glu Ile Cys Gln Glu Val Ile Lys Gln Ser Asn 
145                 150                 155                 160 


Val Gln Ile Leu Val Pro Pro Ala Arg Ala Asp Ile Met Leu Phe Arg 
                165                 170                 175     


Pro Pro Gly Thr Ser Asp Leu Gly Phe Pro Leu Asp Met Thr Asn Gly 
            180                 185                 190         


Ala Ala Leu Ala Ala Asn Ser Asn Gly Ile Ala Gly Ser Met Gln Pro 
        195                 200                 205             


Glu Glu Glu Ala Ala Arg Ala Ala Gly Ala Ala Ile Ala Gly Gln Ala 
    210                 215                 220                 


Ser Leu Pro Val Leu Pro Gly Val Asp Arg Leu Pro Met Val Ala Gly 
225                 230                 235                 240 


Pro Leu Ser Pro Gln Leu Leu Thr Ser Pro Phe Pro Ser Val Ala Ser 
                245                 250                 255     


Ser Ala Pro Pro Leu Thr Gly Lys Arg Gly Arg Gly Arg Pro Arg Lys 
            260                 265                 270         


Ala Asn Leu Leu Asp Ser Met Phe Gly Ser Pro Gly Gly Leu Arg Glu 
        275                 280                 285             


Ala Gly Ile Leu Pro Cys Gly Leu Cys Gly Lys Val Phe Thr Asp Ala 
    290                 295                 300                 


Asn Arg Leu Arg Gln His Glu Ala Gln His Gly Val Thr Ser Leu Gln 
305                 310                 315                 320 


Leu Gly Tyr Ile Asp Leu Pro Pro Pro Arg Leu Gly Glu Asn Gly Leu 
                325                 330                 335     


Pro Ile Ser Glu Asp Pro Asp Gly Pro Arg Lys Arg Ser Arg Thr Arg 
            340                 345                 350         


Lys Gln Val Ala Cys Glu Ile Cys Gly Lys Ile Phe Arg Asp Val Tyr 
        355                 360                 365             


His Leu Asn Arg His Lys Leu Ser His Ser Gly Glu Lys Pro Tyr Ser 
    370                 375                 380                 


Cys Pro Val Cys Gly Leu Arg Phe Lys Arg Lys Asp Arg Met Ser Tyr 
385                 390                 395                 400 


His Val Arg Ser His Asp Gly Ser Val Gly Lys Pro Tyr Ile Cys Gln 
                405                 410                 415     


Ser Cys Gly Lys Gly Phe Ser Arg Pro Asp His Leu Asn Gly His Ile 
            420                 425                 430         


Lys Gln Val His Thr Ser Glu Arg Pro His Lys Cys Gln Thr Cys Asn 
        435                 440                 445             


Ala Ser Phe Ala Thr Arg Asp Arg Leu Arg Ser His Leu Ala Cys His 
    450                 455                 460                 


Glu Asp Lys Val Pro Cys Gln Val Cys Gly Lys Tyr Leu Arg Ala Ala 
465                 470                 475                 480 


Tyr Met Ala Asp His Leu Lys Lys His Ser Glu Gly Pro Ser Asn Phe 
                485                 490                 495     


Cys Ser Ile Cys Asn Arg Glu Gly Gln Lys Cys Ser His Gln Asp Pro 
            500                 505                 510         


Ile Glu Ser Ser Asp Ser Tyr Gly Asp Leu Ser Asp Ala Ser Asp Leu 
        515                 520                 525             


Lys Thr Pro Glu Lys Gln Ser Ala Asn Gly Ser Phe Ser Cys Asp Met 
    530                 535                 540                 


Ala Val Pro Lys Asn Lys Met Glu Ser Asp Gly Glu Lys Lys Tyr Pro 
545                 550                 555                 560 


Cys Pro Glu Cys Gly Ser Phe Phe Arg Ser Lys Ser Tyr Leu Asn Lys 
                565                 570                 575     


His Ile Gln Lys Val His Val Arg Ala Leu Gly Gly Pro Leu Gly Asp 
            580                 585                 590         


Leu Gly Pro Ala Leu Gly Ser Pro Phe Ser Pro Gln Gln Asn Met Ser 
        595                 600                 605             


Leu Leu Glu Ser Phe Gly Phe Gln Ile Val Gln Ser Ala Phe Ala Ser 
    610                 615                 620                 


Ser Leu Val Asp Pro Glu Val Asp Gln Gln Pro Met Gly Pro Glu Gly 
625                 630                 635                 640 


Lys 
    


<210>  3078
<211>  750
<212>  PRT
<213>  homo sapiens

<400>  3078

Met Ser Ser Lys Arg Pro Ala Ser Pro Tyr Gly Glu Ala Asp Gly Glu 
1               5                   10                  15      


Val Ala Met Val Thr Ser Arg Gln Lys Val Glu Glu Glu Glu Ser Asp 
            20                  25                  30          


Gly Leu Pro Ala Phe His Leu Pro Leu His Val Ser Phe Pro Asn Lys 
        35                  40                  45              


Pro His Ser Glu Glu Phe Gln Pro Val Ser Leu Leu Thr Gln Glu Thr 
    50                  55                  60                  


Cys Gly His Arg Thr Pro Thr Ser Gln His Asn Thr Met Glu Val Asp 
65                  70                  75                  80  


Gly Asn Lys Val Met Ser Ser Phe Ala Pro His Asn Ser Ser Thr Ser 
                85                  90                  95      


Pro Gln Lys Ala Glu Glu Gly Gly Arg Gln Ser Gly Glu Ser Leu Ser 
            100                 105                 110         


Ser Thr Ala Leu Gly Thr Pro Glu Arg Arg Lys Gly Ser Leu Ala Asp 
        115                 120                 125             


Val Val Asp Thr Leu Lys Gln Arg Lys Met Glu Glu Leu Ile Lys Asn 
    130                 135                 140                 


Glu Pro Glu Glu Thr Pro Ser Ile Glu Lys Leu Leu Ser Lys Asp Trp 
145                 150                 155                 160 


Lys Asp Lys Leu Leu Ala Met Gly Ser Gly Asn Phe Gly Glu Ile Lys 
                165                 170                 175     


Gly Thr Pro Glu Ser Leu Ala Glu Lys Glu Arg Gln Leu Met Gly Met 
            180                 185                 190         


Ile Asn Gln Leu Thr Ser Leu Arg Glu Gln Leu Leu Ala Ala His Asp 
        195                 200                 205             


Glu Gln Lys Lys Leu Ala Ala Ser Gln Ile Glu Lys Gln Arg Gln Gln 
    210                 215                 220                 


Met Glu Leu Ala Lys Gln Gln Gln Glu Gln Ile Ala Arg Gln Gln Gln 
225                 230                 235                 240 


Gln Leu Leu Gln Gln Gln His Lys Ile Asn Leu Leu Gln Gln Gln Ile 
                245                 250                 255     


Gln Val Gln Gly Gln Leu Pro Pro Leu Met Ile Pro Val Phe Pro Pro 
            260                 265                 270         


Asp Gln Arg Thr Leu Ala Ala Ala Ala Gln Gln Gly Phe Leu Leu Pro 
        275                 280                 285             


Pro Gly Phe Ser Tyr Lys Ala Gly Cys Ser Asp Pro Tyr Pro Val Gln 
    290                 295                 300                 


Leu Ile Pro Thr Thr Met Ala Ala Ala Ala Ala Ala Thr Pro Gly Leu 
305                 310                 315                 320 


Gly Pro Leu Gln Leu Gln Gln Leu Tyr Ala Ala Gln Leu Ala Ala Met 
                325                 330                 335     


Gln Val Ser Pro Gly Gly Lys Leu Pro Gly Ile Pro Gln Gly Asn Leu 
            340                 345                 350         


Gly Ala Ala Val Ser Pro Thr Ser Ile His Thr Asp Lys Ser Thr Asn 
        355                 360                 365             


Ser Pro Pro Pro Lys Ser Lys Asp Glu Val Ala Gln Pro Leu Asn Leu 
    370                 375                 380                 


Ser Ala Lys Pro Lys Thr Ser Asp Gly Lys Ser Pro Thr Ser Pro Thr 
385                 390                 395                 400 


Ser Pro His Met Pro Ala Leu Arg Ile Asn Ser Gly Ala Gly Pro Leu 
                405                 410                 415     


Lys Ala Ser Val Pro Ala Ala Leu Ala Ser Pro Ser Ala Arg Val Ser 
            420                 425                 430         


Thr Ile Gly Tyr Leu Asn Asp His Asp Ala Val Thr Lys Ala Ile Gln 
        435                 440                 445             


Glu Ala Arg Gln Met Lys Glu Gln Leu Arg Arg Glu Gln Gln Val Leu 
    450                 455                 460                 


Asp Gly Lys Val Ala Val Val Asn Ser Leu Gly Leu Asn Asn Cys Arg 
465                 470                 475                 480 


Thr Glu Lys Glu Lys Thr Thr Leu Glu Ser Leu Thr Gln Gln Leu Ala 
                485                 490                 495     


Val Lys Gln Asn Glu Glu Gly Lys Phe Ser His Ala Met Met Asp Phe 
            500                 505                 510         


Asn Leu Ser Gly Asp Ser Asp Gly Ser Ala Gly Val Ser Glu Ser Arg 
        515                 520                 525             


Ile Tyr Arg Glu Ser Arg Gly Arg Gly Ser Asn Glu Pro His Ile Lys 
    530                 535                 540                 


Arg Pro Met Asn Ala Phe Met Val Trp Ala Lys Asp Glu Arg Arg Lys 
545                 550                 555                 560 


Ile Leu Gln Ala Phe Pro Asp Met His Asn Ser Asn Ile Ser Lys Ile 
                565                 570                 575     


Leu Gly Ser Arg Trp Lys Ala Met Thr Asn Leu Glu Lys Gln Pro Tyr 
            580                 585                 590         


Tyr Glu Glu Gln Ala Arg Leu Ser Lys Gln His Leu Glu Lys Tyr Pro 
        595                 600                 605             


Asp Tyr Lys Tyr Lys Pro Arg Pro Lys Arg Thr Cys Leu Val Asp Gly 
    610                 615                 620                 


Lys Lys Leu Arg Ile Gly Glu Tyr Lys Ala Ile Met Arg Asn Arg Arg 
625                 630                 635                 640 


Gln Glu Met Arg Gln Tyr Phe Asn Val Gly Gln Gln Ala Gln Ile Pro 
                645                 650                 655     


Ile Ala Thr Ala Gly Val Val Tyr Pro Gly Ala Ile Ala Met Ala Gly 
            660                 665                 670         


Met Pro Ser Pro His Leu Pro Ser Glu His Ser Ser Val Ser Ser Ser 
        675                 680                 685             


Pro Glu Pro Gly Met Pro Val Ile Gln Ser Thr Tyr Gly Val Lys Gly 
    690                 695                 700                 


Glu Glu Pro His Ile Lys Glu Glu Ile Gln Ala Glu Asp Ile Asn Gly 
705                 710                 715                 720 


Glu Ile Tyr Asp Glu Tyr Asp Glu Glu Glu Asp Asp Pro Asp Val Asp 
                725                 730                 735     


Tyr Gly Ser Asp Ser Glu Asn His Ile Ala Gly Gln Ala Asn 
            740                 745                 750 


<210>  3079
<211>  383
<212>  PRT
<213>  homo sapiens

<400>  3079

Met Ser Leu Val Asp Leu Gly Lys Lys Leu Leu Glu Ala Ala Arg Ala 
1               5                   10                  15      


Gly Gln Asp Asp Glu Val Arg Ile Leu Met Ala Asn Gly Ala Pro Phe 
            20                  25                  30          


Thr Thr Asp Trp Leu Gly Thr Ser Pro Leu His Leu Ala Ala Gln Tyr 
        35                  40                  45              


Gly His Tyr Ser Thr Thr Glu Val Leu Leu Arg Ala Gly Val Ser Arg 
    50                  55                  60                  


Asp Ala Arg Thr Lys Val Asp Arg Thr Pro Leu His Met Ala Ala Ser 
65                  70                  75                  80  


Glu Gly His Ala Ser Ile Val Glu Val Leu Leu Lys His Gly Ala Asp 
                85                  90                  95      


Val Asn Ala Lys Asp Met Leu Lys Met Thr Ala Leu His Trp Ala Thr 
            100                 105                 110         


Glu His Asn His Gln Glu Val Val Glu Leu Leu Ile Lys Tyr Gly Ala 
        115                 120                 125             


Asp Val His Thr Gln Ser Lys Phe Cys Lys Thr Ala Phe Asp Ile Ser 
    130                 135                 140                 


Ile Asp Asn Gly Asn Glu Asp Leu Ala Glu Ile Leu Gln Ile Ala Met 
145                 150                 155                 160 


Gln Asn Gln Ile Asn Thr Asn Pro Glu Ser Pro Asp Thr Val Thr Ile 
                165                 170                 175     


His Ala Ala Thr Pro Gln Phe Ile Ile Gly Pro Gly Gly Val Val Asn 
            180                 185                 190         


Leu Thr Asp Glu Thr Gly Val Ser Ala Val Gln Phe Gly Asn Ser Ser 
        195                 200                 205             


Thr Ser Val Leu Ala Thr Leu Ala Ala Leu Ala Glu Ala Ser Ala Pro 
    210                 215                 220                 


Leu Ser Asn Ser Ser Glu Thr Pro Val Val Ala Thr Glu Glu Val Val 
225                 230                 235                 240 


Thr Ala Glu Ser Val Asp Gly Ala Ile Gln Gln Val Val Ser Ser Gly 
                245                 250                 255     


Gly Gln Gln Val Ile Thr Ile Val Thr Asp Gly Ile Gln Leu Gly Asn 
            260                 265                 270         


Leu His Ser Ile Pro Thr Ser Gly Ile Gly Gln Pro Ile Ile Val Thr 
        275                 280                 285             


Met Pro Asp Gly Gln Gln Val Leu Thr Val Pro Ala Thr Asp Ile Ala 
    290                 295                 300                 


Glu Glu Thr Val Ile Ser Glu Glu Pro Pro Ala Lys Arg Gln Cys Ile 
305                 310                 315                 320 


Glu Ile Ile Glu Asn Arg Val Glu Ser Ala Glu Ile Glu Glu Arg Glu 
                325                 330                 335     


Ala Leu Gln Lys Gln Leu Asp Glu Ala Asn Arg Glu Ala Gln Lys Tyr 
            340                 345                 350         


Arg Gln Gln Leu Leu Lys Lys Glu Gln Glu Ala Glu Ala Tyr Arg Gln 
        355                 360                 365             


Lys Leu Glu Ala Met Thr Arg Leu Gln Thr Asn Lys Glu Ala Val 
    370                 375                 380             


<210>  3080
<211>  3065
<212>  PRT
<213>  homo sapiens

<400>  3080

Met Glu Glu Lys Gln Gln Ile Ile Leu Ala Asn Gln Asp Gly Gly Thr 
1               5                   10                  15      


Val Ala Gly Ala Ala Pro Thr Phe Phe Val Ile Leu Lys Gln Pro Gly 
            20                  25                  30          


Asn Gly Lys Thr Asp Gln Gly Ile Leu Val Thr Asn Gln Asp Ala Cys 
        35                  40                  45              


Ala Leu Ala Ser Ser Val Ser Ser Pro Val Lys Ser Lys Gly Lys Ile 
    50                  55                  60                  


Cys Leu Pro Ala Asp Cys Thr Val Gly Gly Ile Thr Val Thr Leu Asp 
65                  70                  75                  80  


Asn Asn Ser Met Trp Asn Glu Phe Tyr His Arg Ser Thr Glu Met Ile 
                85                  90                  95      


Leu Thr Lys Gln Gly Arg Arg Met Phe Pro Tyr Cys Arg Tyr Trp Ile 
            100                 105                 110         


Thr Gly Leu Asp Ser Asn Leu Lys Tyr Ile Leu Val Met Asp Ile Ser 
        115                 120                 125             


Pro Val Asp Asn His Arg Tyr Lys Trp Asn Gly Arg Trp Trp Glu Pro 
    130                 135                 140                 


Ser Gly Lys Ala Glu Pro His Val Leu Gly Arg Val Phe Ile His Pro 
145                 150                 155                 160 


Glu Ser Pro Ser Thr Gly His Tyr Trp Met His Gln Pro Val Ser Phe 
                165                 170                 175     


Tyr Lys Leu Lys Leu Thr Asn Asn Thr Leu Asp Gln Glu Gly His Ile 
            180                 185                 190         


Ile Leu His Ser Met His Arg Tyr Leu Pro Arg Leu His Leu Val Pro 
        195                 200                 205             


Ala Glu Lys Ala Val Glu Val Ile Gln Leu Asn Gly Pro Gly Val His 
    210                 215                 220                 


Thr Phe Thr Phe Pro Gln Thr Glu Phe Phe Ala Val Thr Ala Tyr Gln 
225                 230                 235                 240 


Asn Ile Gln Ile Thr Gln Leu Lys Ile Asp Tyr Asn Pro Phe Ala Lys 
                245                 250                 255     


Gly Phe Arg Asp Asp Gly Leu Asn Asn Lys Pro Gln Arg Asp Gly Lys 
            260                 265                 270         


Gln Lys Asn Ser Ser Asp Gln Glu Gly Asn Asn Ile Ser Ser Ser Ser 
        275                 280                 285             


Gly His Arg Val Arg Leu Thr Glu Gly Gln Gly Ser Glu Ile Gln Pro 
    290                 295                 300                 


Gly Asp Leu Asp Pro Leu Ser Arg Gly His Glu Thr Ser Gly Lys Gly 
305                 310                 315                 320 


Leu Glu Lys Thr Ser Leu Asn Ile Lys Arg Asp Phe Leu Gly Phe Met 
                325                 330                 335     


Asp Thr Asp Ser Ala Leu Ser Glu Val Pro Gln Leu Lys Gln Glu Ile 
            340                 345                 350         


Ser Glu Cys Leu Ile Ala Ser Ser Phe Glu Asp Asp Ser Arg Val Ala 
        355                 360                 365             


Ser Pro Leu Asp Gln Asn Gly Ser Phe Asn Val Val Ile Lys Glu Glu 
    370                 375                 380                 


Pro Leu Asp Asp Tyr Asp Tyr Glu Leu Gly Glu Cys Pro Glu Gly Val 
385                 390                 395                 400 


Thr Val Lys Gln Glu Glu Thr Asp Glu Glu Thr Asp Val Tyr Ser Asn 
                405                 410                 415     


Ser Asp Asp Asp Pro Ile Leu Glu Lys Gln Leu Lys Arg His Asn Lys 
            420                 425                 430         


Val Asp Asn Pro Glu Ala Asp His Leu Ser Ser Lys Trp Leu Pro Ser 
        435                 440                 445             


Ser Pro Ser Gly Val Ala Lys Ala Lys Met Phe Lys Leu Asp Thr Gly 
    450                 455                 460                 


Lys Met Pro Val Val Tyr Leu Glu Pro Cys Ala Val Thr Arg Ser Thr 
465                 470                 475                 480 


Val Lys Ile Ser Glu Leu Pro Asp Asn Met Leu Ser Thr Ser Arg Lys 
                485                 490                 495     


Asp Lys Ser Ser Met Leu Ala Glu Leu Glu Tyr Leu Pro Thr Tyr Ile 
            500                 505                 510         


Glu Asn Ser Asn Glu Thr Ala Phe Cys Leu Gly Lys Glu Ser Glu Asn 
        515                 520                 525             


Gly Leu Arg Lys His Ser Pro Asp Leu Arg Val Val Gln Lys Tyr Pro 
    530                 535                 540                 


Leu Leu Lys Glu Pro Gln Trp Lys Tyr Pro Asp Ile Ser Asp Ser Ile 
545                 550                 555                 560 


Ser Thr Glu Arg Ile Leu Asp Asp Ser Lys Asp Ser Val Gly Asp Ser 
                565                 570                 575     


Leu Ser Gly Lys Glu Asp Leu Gly Arg Lys Arg Thr Thr Met Leu Lys 
            580                 585                 590         


Ile Ala Thr Ala Ala Lys Val Val Asn Ala Asn Gln Asn Ala Ser Pro 
        595                 600                 605             


Asn Val Pro Gly Lys Arg Gly Arg Pro Arg Lys Leu Lys Leu Cys Lys 
    610                 615                 620                 


Ala Gly Arg Pro Pro Lys Asn Thr Gly Lys Ser Leu Ile Ser Thr Lys 
625                 630                 635                 640 


Asn Thr Pro Val Ser Pro Gly Ser Thr Phe Pro Asp Val Lys Pro Asp 
                645                 650                 655     


Leu Glu Asp Val Asp Gly Val Leu Phe Val Ser Phe Glu Ser Lys Glu 
            660                 665                 670         


Ala Leu Asp Ile His Ala Val Asp Gly Thr Thr Glu Glu Ser Ser Ser 
        675                 680                 685             


Leu Gln Ala Ser Thr Thr Asn Asp Ser Gly Tyr Arg Ala Arg Ile Ser 
    690                 695                 700                 


Gln Leu Glu Lys Glu Leu Ile Glu Asp Leu Lys Thr Leu Arg His Lys 
705                 710                 715                 720 


Gln Val Ile His Pro Gly Leu Gln Glu Val Gly Leu Lys Leu Asn Ser 
                725                 730                 735     


Val Asp Pro Thr Met Ser Ile Asp Leu Lys Tyr Leu Gly Val Gln Leu 
            740                 745                 750         


Pro Leu Ala Pro Ala Thr Ser Phe Pro Phe Trp Asn Leu Thr Gly Thr 
        755                 760                 765             


Asn Pro Ala Ser Pro Asp Ala Gly Phe Pro Phe Val Ser Arg Thr Gly 
    770                 775                 780                 


Lys Thr Asn Asp Phe Thr Lys Ile Lys Gly Trp Arg Gly Lys Phe His 
785                 790                 795                 800 


Ser Ala Ser Ala Ser Arg Asn Glu Gly Gly Asn Ser Glu Ser Ser Leu 
                805                 810                 815     


Lys Asn Arg Ser Ala Phe Cys Ser Asp Lys Leu Asp Glu Tyr Leu Glu 
            820                 825                 830         


Asn Glu Gly Lys Leu Met Glu Thr Ser Met Gly Phe Ser Ser Asn Ala 
        835                 840                 845             


Pro Thr Ser Pro Val Val Tyr Gln Leu Pro Thr Lys Ser Thr Ser Tyr 
    850                 855                 860                 


Val Arg Thr Leu Asp Ser Val Leu Lys Lys Gln Ser Thr Ile Ser Pro 
865                 870                 875                 880 


Ser Thr Ser Tyr Ser Leu Lys Pro His Ser Val Pro Pro Val Ser Arg 
                885                 890                 895     


Lys Ala Lys Ser Gln Asn Arg Gln Ala Thr Phe Ser Gly Arg Thr Lys 
            900                 905                 910         


Ser Ser Tyr Lys Ser Ile Leu Pro Tyr Pro Val Ser Pro Lys Gln Lys 
        915                 920                 925             


Tyr Ser His Val Ile Leu Gly Asp Lys Val Thr Lys Asn Ser Ser Gly 
    930                 935                 940                 


Ile Ile Ser Glu Asn Gln Ala Asn Asn Phe Val Val Pro Thr Leu Asp 
945                 950                 955                 960 


Glu Asn Ile Phe Pro Lys Gln Ile Ser Leu Arg Gln Ala Gln Gln Gln 
                965                 970                 975     


Gln Gln Gln Gln Gln Gly Ser Arg Pro Pro Gly Leu Ser Lys Ser Gln 
            980                 985                 990         


Val Lys Leu Met Asp Leu Glu Asp  Cys Ala Leu Trp Glu  Gly Lys Pro 
        995                 1000                 1005             


Arg Thr  Tyr Ile Thr Glu Glu  Arg Ala Asp Val Ser  Leu Thr Thr 
    1010                 1015                 1020             


Leu Leu  Thr Ala Gln Ala Ser  Leu Lys Thr Lys Pro  Ile His Thr 
    1025                 1030                 1035             


Ile Ile  Arg Lys Arg Ala Pro  Pro Cys Asn Asn Asp  Phe Cys Arg 
    1040                 1045                 1050             


Leu Gly  Cys Val Cys Ser Ser  Leu Ala Leu Glu Lys  Arg Gln Pro 
    1055                 1060                 1065             


Ala His  Cys Arg Arg Pro Asp  Cys Met Phe Gly Cys  Thr Cys Leu 
    1070                 1075                 1080             


Lys Arg  Lys Val Val Leu Val  Lys Gly Gly Ser Lys  Thr Lys His 
    1085                 1090                 1095             


Phe Gln  Arg Lys Ala Ala His  Arg Asp Pro Val Phe  Tyr Asp Thr 
    1100                 1105                 1110             


Leu Gly  Glu Glu Ala Arg Glu  Glu Glu Glu Gly Ile  Arg Glu Glu 
    1115                 1120                 1125             


Glu Glu  Gln Leu Lys Glu Lys  Lys Lys Arg Lys Lys  Leu Glu Tyr 
    1130                 1135                 1140             


Thr Ile  Cys Glu Thr Glu Pro  Glu Gln Pro Val Arg  His Tyr Pro 
    1145                 1150                 1155             


Leu Trp  Val Lys Val Glu Gly  Glu Val Asp Pro Glu  Pro Val Tyr 
    1160                 1165                 1170             


Ile Pro  Thr Pro Ser Val Ile  Glu Pro Met Lys Pro  Leu Leu Leu 
    1175                 1180                 1185             


Pro Gln  Pro Glu Val Leu Ser  Pro Thr Val Lys Gly  Lys Leu Leu 
    1190                 1195                 1200             


Thr Gly  Ile Lys Ser Pro Arg  Ser Tyr Thr Pro Lys  Pro Asn Pro 
    1205                 1210                 1215             


Val Ile  Arg Glu Glu Asp Lys  Asp Pro Val Tyr Leu  Tyr Phe Glu 
    1220                 1225                 1230             


Ser Met  Met Thr Cys Ala Arg  Val Arg Val Tyr Glu  Arg Lys Lys 
    1235                 1240                 1245             


Glu Asp  Gln Arg Gln Pro Ser  Ser Ser Ser Ser Pro  Ser Pro Ser 
    1250                 1255                 1260             


Phe Gln  Gln Gln Thr Ser Cys  His Ser Ser Pro Glu  Asn His Asn 
    1265                 1270                 1275             


Asn Ala  Lys Glu Pro Asp Ser  Glu Gln Gln Pro Leu  Lys Gln Leu 
    1280                 1285                 1290             


Thr Cys  Asp Leu Glu Asp Asp  Ser Asp Lys Leu Gln  Glu Lys Ser 
    1295                 1300                 1305             


Trp Lys  Ser Ser Cys Asn Glu  Gly Glu Ser Ser Ser  Thr Ser Tyr 
    1310                 1315                 1320             


Met His  Gln Arg Ser Pro Gly  Gly Pro Thr Lys Leu  Ile Glu Ile 
    1325                 1330                 1335             


Ile Ser  Asp Cys Asn Trp Glu  Glu Asp Arg Asn Lys  Ile Leu Ser 
    1340                 1345                 1350             


Ile Leu  Ser Gln His Ile Asn  Ser Asn Met Pro Gln  Ser Leu Lys 
    1355                 1360                 1365             


Val Gly  Ser Phe Ile Ile Glu  Leu Ala Ser Gln Arg  Lys Ser Arg 
    1370                 1375                 1380             


Gly Glu  Lys Asn Pro Pro Val  Tyr Ser Ser Arg Val  Lys Ile Ser 
    1385                 1390                 1395             


Met Pro  Ser Cys Gln Asp Gln  Asp Asp Met Ala Glu  Lys Ser Gly 
    1400                 1405                 1410             


Ser Glu  Thr Pro Asp Gly Pro  Leu Ser Pro Gly Lys  Met Glu Asp 
    1415                 1420                 1425             


Ile Ser  Pro Val Gln Thr Asp  Ala Leu Asp Ser Val  Arg Glu Arg 
    1430                 1435                 1440             


Leu His  Gly Gly Lys Gly Leu  Pro Phe Tyr Ala Gly  Leu Ser Pro 
    1445                 1450                 1455             


Ala Gly  Lys Leu Val Ala Tyr  Lys Arg Lys Pro Ser  Ser Ser Thr 
    1460                 1465                 1470             


Ser Gly  Leu Ile Gln Val Ala  Ser Asn Ala Lys Val  Ala Ala Ser 
    1475                 1480                 1485             


Arg Lys  Pro Arg Thr Leu Leu  Pro Ser Thr Ser Asn  Ser Lys Met 
    1490                 1495                 1500             


Ala Ser  Ser Ser Gly Thr Ala  Thr Asn Arg Pro Gly  Lys Asn Leu 
    1505                 1510                 1515             


Lys Ala  Phe Val Pro Ala Lys  Arg Pro Ile Ala Ala  Arg Pro Ser 
    1520                 1525                 1530             


Pro Gly  Gly Val Phe Thr Gln  Phe Val Met Ser Lys  Val Gly Ala 
    1535                 1540                 1545             


Leu Gln  Gln Lys Ile Pro Gly  Val Ser Thr Pro Gln  Thr Leu Ala 
    1550                 1555                 1560             


Gly Thr  Gln Lys Phe Ser Ile  Arg Pro Ser Pro Val  Met Val Val 
    1565                 1570                 1575             


Thr Pro  Val Val Ser Ser Glu  Pro Val Gln Val Cys  Ser Pro Val 
    1580                 1585                 1590             


Thr Ala  Ala Val Thr Thr Thr  Thr Pro Gln Val Phe  Leu Glu Asn 
    1595                 1600                 1605             


Thr Thr  Ala Val Thr Pro Met  Thr Ala Ile Ser Asp  Val Glu Thr 
    1610                 1615                 1620             


Lys Glu  Thr Thr Tyr Ser Ser  Gly Ala Thr Thr Thr  Gly Val Val 
    1625                 1630                 1635             


Glu Val  Ser Glu Thr Asn Thr  Ser Thr Ser Val Thr  Ser Thr Gln 
    1640                 1645                 1650             


Ser Thr  Ala Thr Val Asn Leu  Thr Lys Thr Thr Gly  Ile Thr Thr 
    1655                 1660                 1665             


Pro Val  Ala Ser Val Ala Phe  Pro Lys Ser Leu Val  Ala Ser Pro 
    1670                 1675                 1680             


Ser Thr  Ile Thr Leu Pro Val  Ala Ser Thr Ala Ser  Thr Ser Leu 
    1685                 1690                 1695             


Val Val  Val Thr Ala Ala Ala  Ser Ser Ser Met Val  Thr Thr Pro 
    1700                 1705                 1710             


Thr Ser  Ser Leu Gly Ser Val  Pro Ile Ile Leu Ser  Gly Ile Asn 
    1715                 1720                 1725             


Gly Ser  Pro Pro Val Ser Gln  Arg Pro Glu Asn Ala  Ala Gln Ile 
    1730                 1735                 1740             


Pro Val  Ala Thr Pro Gln Val  Ser Pro Asn Thr Val  Lys Arg Ala 
    1745                 1750                 1755             


Gly Pro  Arg Leu Leu Leu Ile  Pro Val Gln Gln Gly  Ser Pro Thr 
    1760                 1765                 1770             


Leu Arg  Pro Val Ser Asn Thr  Gln Leu Gln Gly His  Arg Met Val 
    1775                 1780                 1785             


Leu Gln  Pro Val Arg Ser Pro  Ser Gly Met Asn Leu  Phe Arg His 
    1790                 1795                 1800             


Pro Asn  Gly Gln Ile Val Gln  Leu Leu Pro Leu His  Gln Leu Arg 
    1805                 1810                 1815             


Gly Ser  Asn Thr Gln Pro Asn  Leu Gln Pro Val Met  Phe Arg Asn 
    1820                 1825                 1830             


Pro Gly  Ser Val Met Gly Ile  Arg Leu Pro Ala Pro  Ser Lys Pro 
    1835                 1840                 1845             


Ser Glu  Thr Pro Pro Ser Ser  Thr Ser Ser Ser Ala  Phe Ser Val 
    1850                 1855                 1860             


Met Asn  Pro Val Ile Gln Ala  Val Gly Ser Ser Ser  Ala Val Asn 
    1865                 1870                 1875             


Val Ile  Thr Gln Ala Pro Ser  Leu Leu Ser Ser Gly  Ala Ser Phe 
    1880                 1885                 1890             


Val Ser  Gln Ala Gly Thr Leu  Thr Leu Arg Ile Ser  Pro Pro Glu 
    1895                 1900                 1905             


Pro Gln  Ser Phe Ala Ser Lys  Thr Gly Ser Glu Thr  Lys Ile Thr 
    1910                 1915                 1920             


Tyr Ser  Ser Gly Gly Gln Pro  Val Gly Thr Ala Ser  Leu Ile Pro 
    1925                 1930                 1935             


Leu Gln  Ser Gly Ser Phe Ala  Leu Leu Gln Leu Pro  Gly Gln Lys 
    1940                 1945                 1950             


Pro Val  Pro Ser Ser Ile Leu  Gln His Val Ala Ser  Leu Gln Met 
    1955                 1960                 1965             


Lys Arg  Glu Ser Gln Asn Pro  Asp Gln Lys Asp Glu  Thr Asn Ser 
    1970                 1975                 1980             


Ile Lys  Arg Glu Gln Glu Thr  Lys Lys Val Leu Gln  Ser Glu Gly 
    1985                 1990                 1995             


Glu Ala  Val Asp Pro Glu Ala  Asn Val Ile Lys Gln  Asn Ser Gly 
    2000                 2005                 2010             


Ala Ala  Thr Ser Glu Glu Thr  Leu Asn Asp Ser Leu  Glu Asp Arg 
    2015                 2020                 2025             


Gly Asp  His Leu Asp Glu Glu  Cys Leu Pro Glu Glu  Gly Cys Ala 
    2030                 2035                 2040             


Thr Val  Lys Pro Ser Glu His  Ser Cys Ile Thr Gly  Ser His Thr 
    2045                 2050                 2055             


Asp Gln  Asp Tyr Lys Asp Val  Asn Glu Glu Tyr Gly  Ala Arg Asn 
    2060                 2065                 2070             


Arg Lys  Ser Ser Lys Glu Lys  Val Ala Val Leu Glu  Val Arg Thr 
    2075                 2080                 2085             


Ile Ser  Glu Lys Ala Ser Asn  Lys Thr Val Gln Asn  Leu Ser Lys 
    2090                 2095                 2100             


Val Gln  His Gln Lys Leu Gly  Asp Val Lys Val Glu  Gln Gln Lys 
    2105                 2110                 2115             


Gly Phe  Asp Asn Pro Glu Glu  Asn Ser Ser Glu Phe  Pro Val Thr 
    2120                 2125                 2130             


Phe Lys  Glu Glu Ser Lys Phe  Glu Leu Ser Gly Ser  Lys Val Met 
    2135                 2140                 2145             


Glu Gln  Gln Ser Asn Leu Gln  Pro Glu Ala Lys Glu  Lys Glu Cys 
    2150                 2155                 2160             


Gly Asp  Ser Leu Glu Lys Asp  Arg Glu Arg Trp Arg  Lys His Leu 
    2165                 2170                 2175             


Lys Gly  Pro Leu Thr Arg Lys  Cys Val Gly Ala Ser  Gln Glu Cys 
    2180                 2185                 2190             


Lys Lys  Glu Ala Asp Glu Gln  Leu Ile Lys Glu Thr  Lys Thr Cys 
    2195                 2200                 2205             


Gln Glu  Asn Ser Asp Val Phe  Gln Gln Glu Gln Gly  Ile Ser Asp 
    2210                 2215                 2220             


Leu Leu  Gly Lys Ser Gly Ile  Thr Glu Asp Ala Arg  Val Leu Lys 
    2225                 2230                 2235             


Thr Glu  Cys Asp Ser Trp Ser  Arg Ile Ser Asn Pro  Ser Ala Phe 
    2240                 2245                 2250             


Ser Ile  Val Pro Arg Arg Ala  Ala Lys Ser Ser Arg  Gly Asn Gly 
    2255                 2260                 2265             


His Phe  Gln Gly His Leu Leu  Leu Pro Gly Glu Gln  Ile Gln Pro 
    2270                 2275                 2280             


Lys Gln  Glu Lys Lys Gly Gly  Arg Ser Ser Ala Asp  Phe Thr Val 
    2285                 2290                 2295             


Leu Asp  Leu Glu Glu Asp Asp  Glu Asp Asp Asn Glu  Lys Thr Asp 
    2300                 2305                 2310             


Asp Ser  Ile Asp Glu Ile Val  Asp Val Val Ser Asp  Tyr Gln Ser 
    2315                 2320                 2325             


Glu Glu  Val Asp Asp Val Glu  Lys Asn Asn Cys Val  Glu Tyr Ile 
    2330                 2335                 2340             


Glu Asp  Asp Glu Glu His Val  Asp Ile Glu Thr Val  Glu Glu Leu 
    2345                 2350                 2355             


Ser Glu  Glu Ile Asn Val Ala  His Leu Lys Thr Thr  Ala Ala His 
    2360                 2365                 2370             


Thr Gln  Ser Phe Lys Gln Pro  Ser Cys Thr His Ile  Ser Ala Asp 
    2375                 2380                 2385             


Glu Lys  Ala Ala Glu Arg Ser  Arg Lys Ala Pro Pro  Ile Pro Leu 
    2390                 2395                 2400             


Lys Leu  Lys Pro Asp Tyr Trp  Ser Asp Lys Leu Gln  Lys Glu Ala 
    2405                 2410                 2415             


Glu Ala  Phe Ala Tyr Tyr Arg  Arg Thr His Thr Ala  Asn Glu Arg 
    2420                 2425                 2430             


Arg Arg  Arg Gly Glu Met Arg  Asp Leu Phe Glu Lys  Leu Lys Ile 
    2435                 2440                 2445             


Thr Leu  Gly Leu Leu His Ser  Ser Lys Val Ser Lys  Ser Leu Ile 
    2450                 2455                 2460             


Leu Thr  Arg Ala Phe Ser Glu  Ile Gln Gly Leu Thr  Asp Gln Ala 
    2465                 2470                 2475             


Asp Lys  Leu Ile Gly Gln Lys  Asn Leu Leu Thr Arg  Lys Arg Asn 
    2480                 2485                 2490             


Ile Leu  Ile Arg Lys Val Ser  Ser Leu Ser Gly Lys  Thr Glu Glu 
    2495                 2500                 2505             


Val Val  Leu Lys Lys Leu Glu  Tyr Ile Tyr Ala Lys  Gln Gln Ala 
    2510                 2515                 2520             


Leu Glu  Ala Gln Lys Arg Lys  Lys Lys Met Gly Ser  Asp Glu Phe 
    2525                 2530                 2535             


Asp Ile  Ser Pro Arg Ile Ser  Lys Gln Gln Glu Gly  Ser Ser Ala 
    2540                 2545                 2550             


Ser Ser  Val Asp Leu Gly Gln  Met Phe Ile Asn Asn  Arg Arg Gly 
    2555                 2560                 2565             


Lys Pro  Leu Ile Leu Ser Arg  Lys Lys Asp Gln Ala  Thr Glu Asn 
    2570                 2575                 2580             


Thr Ser  Pro Leu Asn Thr Pro  His Thr Ser Ala Asn  Leu Val Met 
    2585                 2590                 2595             


Thr Pro  Gln Gly Gln Leu Leu  Thr Leu Lys Gly Pro  Leu Phe Ser 
    2600                 2605                 2610             


Gly Pro  Val Val Ala Val Ser  Pro Asp Leu Leu Glu  Ser Asp Leu 
    2615                 2620                 2625             


Lys Pro  Gln Val Ala Gly Ser  Ala Val Ala Leu Pro  Glu Asn Asp 
    2630                 2635                 2640             


Asp Leu  Phe Met Met Pro Arg  Ile Val Asn Val Thr  Ser Leu Ala 
    2645                 2650                 2655             


Thr Glu  Gly Gly Leu Val Asp  Met Gly Gly Ser Lys  Tyr Pro His 
    2660                 2665                 2670             


Glu Val  Pro Asp Ser Lys Pro  Ser Asp His Leu Lys  Asp Thr Val 
    2675                 2680                 2685             


Arg Asn  Glu Asp Asn Ser Leu  Glu Asp Lys Gly Arg  Ile Ser Ser 
    2690                 2695                 2700             


Arg Gly  Asn Arg Asp Gly Arg  Val Thr Leu Gly Pro  Thr Gln Val 
    2705                 2710                 2715             


Phe Leu  Ala Asn Lys Asp Ser  Gly Tyr Pro Gln Ile  Val Asp Val 
    2720                 2725                 2730             


Ser Asn  Met Gln Lys Ala Gln  Glu Phe Leu Pro Lys  Lys Ile Ser 
    2735                 2740                 2745             


Gly Asp  Met Arg Gly Ile Gln  Tyr Lys Trp Lys Glu  Ser Glu Ser 
    2750                 2755                 2760             


Arg Gly  Glu Arg Val Lys Ser  Lys Asp Ser Ser Phe  His Lys Leu 
    2765                 2770                 2775             


Lys Met  Lys Asp Leu Lys Asp  Ser Ser Ile Glu Met  Glu Leu Arg 
    2780                 2785                 2790             


Lys Val  Thr Ser Ala Ile Glu  Glu Ala Ala Leu Asp  Ser Ser Glu 
    2795                 2800                 2805             


Leu Leu  Thr Asn Met Glu Asp  Glu Asp Asp Thr Asp  Glu Thr Leu 
    2810                 2815                 2820             


Thr Ser  Leu Leu Asn Glu Ile  Ala Phe Leu Asn Gln  Gln Leu Asn 
    2825                 2830                 2835             


Asp Asp  Ser Val Gly Leu Ala  Glu Leu Pro Ser Ser  Met Asp Thr 
    2840                 2845                 2850             


Glu Phe  Pro Gly Asp Ala Arg  Arg Ala Phe Ile Ser  Lys Val Pro 
    2855                 2860                 2865             


Pro Gly  Ser Arg Ala Thr Phe  Gln Val Glu His Leu  Gly Thr Gly 
    2870                 2875                 2880             


Leu Lys  Glu Leu Pro Asp Val  Gln Gly Glu Ser Asp  Ser Ile Ser 
    2885                 2890                 2895             


Pro Leu  Leu Leu His Leu Glu  Asp Asp Asp Phe Ser  Glu Asn Glu 
    2900                 2905                 2910             


Lys Gln  Leu Ala Glu Pro Ala  Ser Glu Pro Asp Val  Leu Lys Ile 
    2915                 2920                 2925             


Val Ile  Asp Ser Glu Ile Lys  Asp Ser Leu Leu Ser  Asn Lys Lys 
    2930                 2935                 2940             


Ala Ile  Asp Gly Gly Lys Asn  Thr Ser Gly Leu Pro  Ala Glu Pro 
    2945                 2950                 2955             


Glu Ser  Val Ser Ser Pro Pro  Thr Leu His Met Lys  Thr Gly Leu 
    2960                 2965                 2970             


Glu Asn  Ser Asn Ser Thr Asp  Thr Leu Trp Arg Pro  Met Pro Lys 
    2975                 2980                 2985             


Leu Ala  Pro Leu Gly Leu Lys  Val Ala Asn Pro Ser  Ser Asp Ala 
    2990                 2995                 3000             


Asp Gly  Gln Ser Leu Lys Val  Met Pro Cys Leu Ala  Pro Ile Ala 
    3005                 3010                 3015             


Ala Lys  Val Gly Ser Val Gly  His Lys Met Asn Leu  Thr Gly Asn 
    3020                 3025                 3030             


Asp Gln  Glu Gly Arg Glu Ser  Lys Val Met Pro Thr  Leu Ala Pro 
    3035                 3040                 3045             


Val Val  Ala Lys Leu Gly Asn  Ser Gly Ala Ser Pro  Ser Ser Ala 
    3050                 3055                 3060             


Gly Lys  
    3065 


<210>  3081
<211>  290
<212>  PRT
<213>  homo sapiens

<400>  3081

Met Val Leu Leu His Val Lys Arg Gly Asp Glu Ser Gln Phe Leu Leu 
1               5                   10                  15      


Gln Ala Pro Gly Ser Thr Glu Leu Glu Glu Leu Thr Val Gln Val Ala 
            20                  25                  30          


Arg Val Tyr Asn Gly Arg Leu Lys Val Gln Arg Leu Cys Ser Glu Met 
        35                  40                  45              


Glu Glu Leu Ala Glu His Gly Ile Phe Leu Pro Pro Asn Met Gln Gly 
    50                  55                  60                  


Leu Thr Asp Asp Gln Ile Glu Glu Leu Lys Leu Lys Asp Glu Trp Gly 
65                  70                  75                  80  


Glu Lys Cys Val Pro Ser Gly Gly Ala Val Phe Lys Lys Asp Asp Ile 
                85                  90                  95      


Gly Arg Arg Asn Gly Gln Ala Pro Asn Glu Lys Met Lys Gln Val Leu 
            100                 105                 110         


Lys Lys Thr Ile Glu Glu Ala Lys Ala Ile Ile Ser Lys Lys Gln Val 
        115                 120                 125             


Glu Ala Gly Val Cys Val Thr Met Glu Met Val Lys Asp Ala Leu Asp 
    130                 135                 140                 


Gln Leu Arg Gly Ala Val Met Ile Val Tyr Pro Met Gly Leu Pro Pro 
145                 150                 155                 160 


Tyr Asp Pro Ile Arg Met Glu Phe Glu Asn Lys Glu Asp Leu Ser Gly 
                165                 170                 175     


Thr Gln Ala Gly Leu Asn Val Ile Lys Glu Ala Glu Ala Gln Leu Trp 
            180                 185                 190         


Trp Ala Ala Lys Glu Leu Arg Arg Thr Lys Lys Leu Ser Asp Tyr Val 
        195                 200                 205             


Gly Lys Asn Glu Lys Thr Lys Ile Ile Ala Lys Ile Gln Gln Arg Gly 
    210                 215                 220                 


Gln Gly Ala Pro Ala Arg Glu Pro Ile Ile Ser Ser Glu Glu Gln Lys 
225                 230                 235                 240 


Gln Leu Met Leu Tyr Tyr His Arg Arg Gln Glu Glu Leu Lys Arg Leu 
                245                 250                 255     


Glu Glu Asn Asp Asp Asp Ala Tyr Leu Asn Ser Pro Trp Ala Asp Asn 
            260                 265                 270         


Thr Ala Leu Lys Arg His Phe His Gly Val Lys Asp Ile Lys Trp Arg 
        275                 280                 285             


Pro Arg 
    290 


<210>  3082
<211>  439
<212>  PRT
<213>  homo sapiens

<400>  3082

Met Ala Trp Pro Cys Ile Thr Arg Ala Cys Cys Ile Ala Arg Phe Trp 
1               5                   10                  15      


Asn Gln Leu Asp Lys Ala Asp Ile Ala Val Pro Leu Val Phe Thr Lys 
            20                  25                  30          


Tyr Ser Glu Ala Thr Glu His Pro Gly Ala Pro Pro Gln Pro Pro Pro 
        35                  40                  45              


Pro Gln Gln Gln Ala Gln Pro Ala Leu Ala Pro Pro Ser Ala Arg Ala 
    50                  55                  60                  


Val Ala Ile Glu Thr Gln Pro Ala Gln Gly Glu Leu Asp Ala Val Ala 
65                  70                  75                  80  


Arg Ala Thr Gly Pro Ala Pro Gly Pro Thr Gly Glu Arg Glu Pro Ala 
                85                  90                  95      


Ala Gly Pro Gly Arg Ser Gly Pro Gly Pro Gly Leu Gly Ser Gly Ser 
            100                 105                 110         


Thr Ser Gly Pro Ala Asp Ser Val Met Arg Gln Asp Tyr Arg Ala Trp 
        115                 120                 125             


Lys Val Gln Arg Pro Glu Pro Ser Cys Arg Pro Arg Ser Glu Tyr Gln 
    130                 135                 140                 


Pro Ser Asp Ala Pro Phe Glu Arg Glu Thr Gln Tyr Gln Lys Asp Phe 
145                 150                 155                 160 


Arg Ala Trp Pro Leu Pro Arg Arg Gly Asp His Pro Trp Ile Pro Lys 
                165                 170                 175     


Pro Val Gln Ile Ser Ala Ala Ser Gln Ala Ser Ala Pro Ile Leu Gly 
            180                 185                 190         


Ala Pro Lys Arg Arg Pro Gln Ser Gln Glu Arg Trp Pro Val Gln Ala 
        195                 200                 205             


Ala Ala Glu Ala Arg Glu Gln Glu Ala Ala Pro Gly Gly Ala Gly Gly 
    210                 215                 220                 


Leu Ala Ala Gly Lys Ala Ser Gly Ala Asp Glu Arg Asp Thr Arg Arg 
225                 230                 235                 240 


Lys Ala Gly Pro Ala Trp Ile Val Arg Arg Ala Glu Gly Leu Gly His 
                245                 250                 255     


Glu Gln Thr Pro Leu Pro Ala Ala Gln Ala Gln Val Gln Ala Thr Gly 
            260                 265                 270         


Pro Glu Ala Gly Arg Gly Arg Ala Ala Ala Asp Ala Leu Asn Arg Gln 
        275                 280                 285             


Ile Arg Glu Glu Val Ala Ser Ala Val Ser Ser Ser Tyr Arg Asn Glu 
    290                 295                 300                 


Phe Arg Ala Trp Thr Asp Ile Lys Pro Val Lys Pro Ile Lys Ala Lys 
305                 310                 315                 320 


Pro Gln Tyr Lys Pro Pro Asp Asp Lys Met Val His Glu Thr Ser Tyr 
                325                 330                 335     


Ser Ala Gln Phe Lys Gly Glu Ala Ser Lys Pro Thr Thr Ala Asp Asn 
            340                 345                 350         


Lys Val Ile Asp Arg Arg Arg Ile Arg Ser Leu Tyr Ser Glu Pro Phe 
        355                 360                 365             


Lys Glu Pro Pro Lys Val Glu Lys Pro Ser Val Gln Ser Ser Lys Pro 
    370                 375                 380                 


Lys Lys Thr Ser Ala Ser His Lys Pro Thr Arg Lys Ala Lys Asp Lys 
385                 390                 395                 400 


Gln Ala Val Ser Gly Gln Ala Ala Lys Lys Lys Ser Ala Glu Gly Pro 
                405                 410                 415     


Ser Thr Thr Lys Pro Asp Asp Lys Glu Gln Ser Lys Glu Met Asn Asn 
            420                 425                 430         


Lys Leu Ala Glu Ala Lys Glu 
        435                 


<210>  3083
<211>  813
<212>  PRT
<213>  homo sapiens

<400>  3083

Met Ala Trp Pro Cys Ile Thr Arg Ala Cys Cys Ile Ala Arg Phe Trp 
1               5                   10                  15      


Asn Gln Leu Asp Lys Ala Asp Ile Ala Val Pro Leu Val Phe Thr Lys 
            20                  25                  30          


Tyr Ser Glu Ala Thr Glu His Pro Gly Ala Pro Pro Gln Pro Pro Pro 
        35                  40                  45              


Pro Gln Gln Gln Ala Gln Pro Ala Leu Ala Pro Pro Ser Ala Arg Ala 
    50                  55                  60                  


Val Ala Ile Glu Thr Gln Pro Ala Gln Gly Glu Leu Asp Ala Val Ala 
65                  70                  75                  80  


Arg Ala Thr Gly Pro Ala Pro Gly Pro Thr Gly Glu Arg Glu Pro Ala 
                85                  90                  95      


Ala Gly Pro Gly Arg Ser Gly Pro Gly Pro Gly Leu Gly Ser Gly Ser 
            100                 105                 110         


Thr Ser Gly Pro Ala Asp Ser Val Met Arg Gln Asp Tyr Arg Ala Trp 
        115                 120                 125             


Lys Val Gln Arg Pro Glu Pro Ser Cys Arg Pro Arg Ser Glu Tyr Gln 
    130                 135                 140                 


Pro Ser Asp Ala Pro Phe Glu Arg Glu Thr Gln Tyr Gln Lys Asp Phe 
145                 150                 155                 160 


Arg Ala Trp Pro Leu Pro Arg Arg Gly Asp His Pro Trp Ile Pro Lys 
                165                 170                 175     


Pro Val Gln Ile Ser Ala Ala Ser Gln Ala Ser Ala Pro Ile Leu Gly 
            180                 185                 190         


Ala Pro Lys Arg Arg Pro Gln Ser Gln Glu Arg Trp Pro Val Gln Ala 
        195                 200                 205             


Ala Ala Glu Ala Arg Glu Gln Glu Ala Ala Pro Gly Gly Ala Gly Gly 
    210                 215                 220                 


Leu Ala Ala Gly Lys Ala Ser Gly Ala Asp Glu Arg Asp Thr Arg Arg 
225                 230                 235                 240 


Lys Ala Gly Pro Ala Trp Ile Val Arg Arg Ala Glu Gly Leu Gly His 
                245                 250                 255     


Glu Gln Thr Pro Leu Pro Ala Ala Gln Ala Gln Val Gln Ala Thr Gly 
            260                 265                 270         


Pro Glu Ala Gly Arg Gly Arg Ala Ala Ala Asp Ala Leu Asn Arg Gln 
        275                 280                 285             


Ile Arg Glu Glu Val Ala Ser Ala Val Ser Ser Ser Tyr Arg Asn Glu 
    290                 295                 300                 


Phe Arg Ala Trp Thr Asp Ile Lys Pro Val Lys Pro Ile Lys Ala Lys 
305                 310                 315                 320 


Pro Gln Tyr Lys Pro Pro Asp Asp Lys Met Val His Glu Thr Ser Tyr 
                325                 330                 335     


Ser Ala Gln Phe Lys Gly Glu Ala Ser Lys Pro Thr Thr Ala Asp Asn 
            340                 345                 350         


Lys Val Ile Asp Arg Arg Arg Ile Arg Ser Leu Tyr Ser Glu Pro Phe 
        355                 360                 365             


Lys Glu Pro Pro Lys Val Glu Lys Pro Ser Val Gln Ser Ser Lys Pro 
    370                 375                 380                 


Lys Lys Thr Ser Ala Ser His Lys Pro Thr Arg Lys Ala Lys Asp Lys 
385                 390                 395                 400 


Gln Ala Val Ser Gly Gln Ala Ala Lys Lys Lys Ser Ala Glu Gly Pro 
                405                 410                 415     


Ser Thr Thr Lys Pro Asp Asp Lys Glu Gln Ser Lys Glu Met Asn Asn 
            420                 425                 430         


Lys Leu Ala Glu Ala Lys Glu Ser Leu Ala Gln Pro Val Ser Asp Ser 
        435                 440                 445             


Ser Lys Thr Gln Gly Pro Val Ala Thr Glu Pro Asp Lys Asp Gln Gly 
    450                 455                 460                 


Ser Val Val Pro Gly Leu Leu Lys Gly Gln Gly Pro Met Val Gln Glu 
465                 470                 475                 480 


Pro Leu Lys Lys Gln Gly Ser Val Val Pro Gly Pro Pro Lys Asp Leu 
                485                 490                 495     


Gly Pro Met Ile Pro Leu Pro Val Lys Asp Gln Asp His Thr Val Pro 
            500                 505                 510         


Glu Pro Leu Lys Asn Glu Ser Pro Val Ile Ser Ala Pro Val Lys Asp 
        515                 520                 525             


Gln Gly Pro Ser Val Pro Val Pro Pro Lys Asn Gln Ser Pro Met Val 
    530                 535                 540                 


Pro Ala Lys Val Lys Asp Gln Gly Ser Val Val Pro Glu Ser Leu Lys 
545                 550                 555                 560 


Asp Gln Gly Pro Arg Ile Pro Glu Pro Val Lys Asn Gln Ala Pro Met 
                565                 570                 575     


Val Pro Ala Pro Val Lys Asp Glu Gly Pro Met Val Ser Ala Ser Val 
            580                 585                 590         


Lys Asp Gln Gly Pro Met Val Ser Ala Pro Val Lys Asp Gln Gly Pro 
        595                 600                 605             


Ile Val Pro Ala Pro Val Lys Gly Glu Gly Pro Ile Val Pro Ala Pro 
    610                 615                 620                 


Val Lys Asp Glu Gly Pro Met Val Ser Ala Pro Ile Lys Asp Gln Asp 
625                 630                 635                 640 


Pro Met Val Pro Glu His Pro Lys Asp Glu Ser Ala Met Ala Thr Ala 
                645                 650                 655     


Pro Ile Lys Asn Gln Gly Ser Met Val Ser Glu Pro Val Lys Asn Gln 
            660                 665                 670         


Gly Leu Val Val Ser Gly Pro Val Lys Asp Gln Asp Val Val Val Pro 
        675                 680                 685             


Glu His Ala Lys Val His Asp Ser Ala Val Val Ala Pro Val Lys Asn 
    690                 695                 700                 


Gln Gly Pro Val Val Pro Glu Ser Val Lys Asn Gln Asp Pro Ile Leu 
705                 710                 715                 720 


Pro Val Leu Val Lys Asp Gln Gly Pro Thr Val Leu Gln Pro Pro Lys 
                725                 730                 735     


Asn Gln Gly Arg Ile Val Pro Glu Pro Leu Lys Asn Gln Val Pro Ile 
            740                 745                 750         


Val Pro Val Pro Leu Lys Asp Gln Asp Pro Leu Val Pro Val Pro Ala 
        755                 760                 765             


Lys Asp Gln Gly Pro Ala Val Pro Glu Pro Leu Lys Thr Gln Gly Pro 
    770                 775                 780                 


Arg Asp Pro Gln Leu Pro Thr Val Ser Pro Leu Pro Arg Val Met Ile 
785                 790                 795                 800 


Pro Thr Ala Pro His Thr Glu Tyr Ile Glu Ser Ser Pro 
                805                 810             


<210>  3084
<211>  828
<212>  PRT
<213>  homo sapiens

<400>  3084

Met Thr Gly Ser Asn Ser His Ile Thr Ile Leu Thr Leu Lys Val Leu 
1               5                   10                  15      


Pro His Phe Glu Ser Leu Gly Lys Gln Glu Lys Ile Pro Asn Lys Met 
            20                  25                  30          


Ser Ala Phe Arg Asn His Cys Pro His Leu Asp Ser Val Gly Glu Ile 
        35                  40                  45              


Thr Lys Glu Asp Leu Ile Gln Lys Ser Leu Gly Thr Cys Gln Asp Cys 
    50                  55                  60                  


Lys Val Gln Gly Pro Asn Leu Trp Ala Cys Leu Glu Asn Arg Cys Ser 
65                  70                  75                  80  


Tyr Val Gly Cys Gly Glu Ser Gln Val Asp His Ser Thr Ile His Ser 
                85                  90                  95      


Gln Glu Thr Lys His Tyr Leu Thr Val Asn Leu Thr Thr Leu Arg Val 
            100                 105                 110         


Trp Cys Tyr Ala Cys Ser Lys Glu Val Phe Leu Asp Arg Lys Leu Gly 
        115                 120                 125             


Thr Gln Pro Ser Leu Pro His Val Arg Gln Pro His Gln Ile Gln Glu 
    130                 135                 140                 


Asn Ser Val Gln Asp Phe Lys Ile Pro Ser Asn Thr Thr Leu Lys Thr 
145                 150                 155                 160 


Pro Leu Val Ala Val Phe Asp Asp Leu Asp Ile Glu Ala Asp Glu Glu 
                165                 170                 175     


Asp Glu Leu Arg Ala Arg Gly Leu Thr Gly Leu Lys Asn Ile Gly Asn 
            180                 185                 190         


Thr Cys Tyr Met Asn Ala Ala Leu Gln Ala Leu Ser Asn Cys Pro Pro 
        195                 200                 205             


Leu Thr Gln Phe Phe Leu Asp Cys Gly Gly Leu Ala Arg Thr Asp Lys 
    210                 215                 220                 


Lys Pro Ala Ile Cys Lys Ser Tyr Leu Lys Leu Met Thr Glu Leu Trp 
225                 230                 235                 240 


His Lys Ser Arg Pro Gly Ser Val Val Pro Thr Thr Leu Phe Gln Gly 
                245                 250                 255     


Ile Lys Thr Val Asn Pro Thr Phe Arg Gly Tyr Ser Gln Gln Asp Ala 
            260                 265                 270         


Gln Glu Phe Leu Arg Cys Leu Met Asp Leu Leu His Glu Glu Leu Lys 
        275                 280                 285             


Glu Gln Val Met Glu Val Glu Glu Asp Pro Gln Thr Ile Thr Thr Glu 
    290                 295                 300                 


Glu Thr Met Glu Glu Asp Lys Ser Gln Ser Asp Val Asp Phe Gln Ser 
305                 310                 315                 320 


Cys Glu Ser Cys Ser Asn Ser Asp Arg Ala Glu Asn Glu Asn Gly Ser 
                325                 330                 335     


Arg Cys Phe Ser Glu Asp Asn Asn Glu Thr Thr Met Leu Ile Gln Asp 
            340                 345                 350         


Asp Glu Asn Asn Ser Glu Met Ser Lys Asp Trp Gln Lys Glu Lys Met 
        355                 360                 365             


Cys Asn Lys Ile Asn Lys Val Asn Ser Glu Gly Glu Phe Asp Lys Asp 
    370                 375                 380                 


Arg Asp Ser Ile Ser Glu Thr Val Asp Leu Asn Asn Gln Glu Thr Val 
385                 390                 395                 400 


Lys Val Gln Ile His Ser Arg Ala Ser Glu Tyr Ile Thr Asp Val His 
                405                 410                 415     


Ser Asn Asp Leu Ser Thr Pro Gln Ile Leu Pro Ser Asn Glu Gly Val 
            420                 425                 430         


Asn Pro Arg Leu Ser Ala Ser Pro Pro Lys Ser Gly Asn Leu Trp Pro 
        435                 440                 445             


Gly Leu Ala Pro Pro His Lys Lys Ala Gln Ser Ala Ser Pro Lys Arg 
    450                 455                 460                 


Lys Lys Gln His Lys Lys Tyr Arg Ser Val Ile Ser Asp Ile Phe Asp 
465                 470                 475                 480 


Gly Thr Ile Ile Ser Ser Val Gln Cys Leu Thr Cys Asp Arg Val Ser 
                485                 490                 495     


Val Thr Leu Glu Thr Phe Gln Asp Leu Ser Leu Pro Ile Pro Gly Lys 
            500                 505                 510         


Glu Asp Leu Ala Lys Leu His Ser Ser Ser His Pro Thr Ser Ile Val 
        515                 520                 525             


Lys Ala Gly Ser Cys Gly Glu Ala Tyr Ala Pro Gln Gly Trp Ile Ala 
    530                 535                 540                 


Phe Phe Met Glu Tyr Val Lys Ser Trp Phe Trp Gly Pro Val Val Thr 
545                 550                 555                 560 


Leu Gln Asp Cys Leu Ala Ala Phe Phe Ala Arg Asp Glu Leu Lys Gly 
                565                 570                 575     


Asp Asn Met Tyr Ser Cys Glu Lys Cys Lys Lys Leu Arg Asn Gly Val 
            580                 585                 590         


Lys Phe Cys Lys Val Gln Asn Phe Pro Glu Ile Leu Cys Ile His Leu 
        595                 600                 605             


Lys Arg Phe Arg His Glu Leu Met Phe Ser Thr Lys Ile Ser Thr His 
    610                 615                 620                 


Val Ser Phe Pro Leu Glu Gly Leu Asp Leu Gln Pro Phe Leu Ala Lys 
625                 630                 635                 640 


Asp Ser Pro Ala Gln Ile Val Thr Tyr Asp Leu Leu Ser Val Ile Cys 
                645                 650                 655     


His His Gly Thr Ala Ser Ser Gly His Tyr Ile Ala Tyr Cys Arg Asn 
            660                 665                 670         


Asn Leu Asn Asn Leu Trp Tyr Glu Phe Asp Asp Gln Ser Val Thr Glu 
        675                 680                 685             


Val Ser Glu Ser Thr Val Gln Asn Ala Glu Ala Tyr Val Leu Phe Tyr 
    690                 695                 700                 


Arg Lys Ser Ser Glu Glu Ala Gln Lys Glu Arg Arg Arg Ile Ser Asn 
705                 710                 715                 720 


Leu Leu Asn Ile Met Glu Pro Ser Leu Leu Gln Phe Tyr Ile Ser Arg 
                725                 730                 735     


Gln Trp Leu Asn Lys Phe Lys Thr Phe Ala Glu Pro Gly Pro Ile Ser 
            740                 745                 750         


Asn Asn Asp Phe Leu Cys Ile His Gly Gly Val Pro Pro Arg Lys Ala 
        755                 760                 765             


Gly Tyr Ile Glu Asp Leu Val Leu Met Leu Pro Gln Asn Ile Trp Asp 
    770                 775                 780                 


Asn Leu Tyr Ser Arg Tyr Gly Gly Gly Pro Ala Val Asn His Leu Tyr 
785                 790                 795                 800 


Ile Cys His Thr Cys Gln Ile Glu Ala Glu Lys Ile Glu Lys Arg Arg 
                805                 810                 815     


Lys Thr Glu Leu Glu Ile Phe Ile Arg Val Lys Lys 
            820                 825             


<210>  3085
<211>  911
<212>  PRT
<213>  homo sapiens

<400>  3085

Met Ser Ala Phe Arg Asn His Cys Pro His Leu Asp Ser Val Gly Glu 
1               5                   10                  15      


Ile Thr Lys Glu Asp Leu Ile Gln Lys Ser Leu Gly Thr Cys Gln Asp 
            20                  25                  30          


Cys Lys Val Gln Gly Pro Asn Leu Trp Ala Cys Leu Glu Asn Arg Cys 
        35                  40                  45              


Ser Tyr Val Gly Cys Gly Glu Ser Gln Val Asp His Ser Thr Ile His 
    50                  55                  60                  


Ser Gln Glu Thr Lys His Tyr Leu Thr Val Asn Leu Thr Thr Leu Arg 
65                  70                  75                  80  


Val Trp Cys Tyr Ala Cys Ser Lys Glu Val Phe Leu Asp Arg Lys Leu 
                85                  90                  95      


Gly Thr Gln Pro Ser Leu Pro His Val Arg Gln Pro His Gln Ile Gln 
            100                 105                 110         


Glu Asn Ser Val Gln Asp Phe Lys Ile Pro Ser Asn Thr Thr Leu Lys 
        115                 120                 125             


Thr Pro Leu Val Ala Val Phe Asp Asp Leu Asp Ile Glu Ala Asp Glu 
    130                 135                 140                 


Glu Asp Glu Leu Arg Ala Arg Gly Leu Thr Gly Leu Lys Asn Ile Gly 
145                 150                 155                 160 


Asn Thr Cys Tyr Met Asn Ala Ala Leu Gln Ala Leu Ser Asn Cys Pro 
                165                 170                 175     


Pro Leu Thr Gln Phe Phe Leu Asp Cys Gly Gly Leu Ala Arg Thr Asp 
            180                 185                 190         


Lys Lys Pro Ala Ile Cys Lys Ser Tyr Leu Lys Leu Met Thr Glu Leu 
        195                 200                 205             


Trp His Lys Ser Arg Pro Gly Ser Val Val Pro Thr Thr Leu Phe Gln 
    210                 215                 220                 


Gly Ile Lys Thr Val Asn Pro Thr Phe Arg Gly Tyr Ser Gln Gln Asp 
225                 230                 235                 240 


Ala Gln Glu Phe Leu Arg Cys Leu Met Asp Leu Leu His Glu Glu Leu 
                245                 250                 255     


Lys Glu Gln Val Met Glu Val Glu Glu Asp Pro Gln Thr Ile Thr Thr 
            260                 265                 270         


Glu Glu Thr Met Glu Glu Asp Lys Ser Gln Ser Asp Val Asp Phe Gln 
        275                 280                 285             


Ser Cys Glu Ser Cys Ser Asn Ser Asp Arg Ala Glu Asn Glu Asn Gly 
    290                 295                 300                 


Ser Arg Cys Phe Ser Glu Asp Asn Asn Glu Thr Thr Met Leu Ile Gln 
305                 310                 315                 320 


Asp Asp Glu Asn Asn Ser Glu Met Ser Lys Asp Trp Gln Lys Glu Lys 
                325                 330                 335     


Met Cys Asn Lys Ile Asn Lys Val Asn Ser Glu Gly Glu Phe Asp Lys 
            340                 345                 350         


Asp Arg Asp Ser Ile Ser Glu Thr Val Asp Leu Asn Asn Gln Glu Thr 
        355                 360                 365             


Val Lys Val Gln Ile His Ser Arg Ala Ser Glu Tyr Ile Thr Asp Val 
    370                 375                 380                 


His Ser Asn Asp Leu Ser Thr Pro Gln Ile Leu Pro Ser Asn Glu Gly 
385                 390                 395                 400 


Val Asn Pro Arg Leu Ser Ala Ser Pro Pro Lys Ser Gly Asn Leu Trp 
                405                 410                 415     


Pro Gly Leu Ala Pro Pro His Lys Lys Ala Gln Ser Ala Ser Pro Lys 
            420                 425                 430         


Arg Lys Lys Gln His Lys Lys Tyr Arg Ser Val Ile Ser Asp Ile Phe 
        435                 440                 445             


Asp Gly Thr Ile Ile Ser Ser Val Gln Cys Leu Thr Cys Asp Arg Val 
    450                 455                 460                 


Ser Val Thr Leu Glu Thr Phe Gln Asp Leu Ser Leu Pro Ile Pro Gly 
465                 470                 475                 480 


Lys Glu Asp Leu Ala Lys Leu His Ser Ser Ser His Pro Thr Ser Ile 
                485                 490                 495     


Val Lys Ala Gly Ser Cys Gly Glu Ala Tyr Ala Pro Gln Gly Trp Ile 
            500                 505                 510         


Ala Phe Phe Met Glu Tyr Val Lys Arg Phe Val Val Ser Cys Val Pro 
        515                 520                 525             


Ser Trp Phe Trp Gly Pro Val Val Thr Leu Gln Asp Cys Leu Ala Ala 
    530                 535                 540                 


Phe Phe Ala Arg Asp Glu Leu Lys Gly Asp Asn Met Tyr Ser Cys Glu 
545                 550                 555                 560 


Lys Cys Lys Lys Leu Arg Asn Gly Val Lys Phe Cys Lys Val Gln Asn 
                565                 570                 575     


Phe Pro Glu Ile Leu Cys Ile His Leu Lys Arg Phe Arg His Glu Leu 
            580                 585                 590         


Met Phe Ser Thr Lys Ile Ser Thr His Val Ser Phe Pro Leu Glu Gly 
        595                 600                 605             


Leu Asp Leu Gln Pro Phe Leu Ala Lys Asp Ser Pro Ala Gln Ile Val 
    610                 615                 620                 


Thr Tyr Asp Leu Leu Ser Val Ile Cys His His Gly Thr Ala Ser Ser 
625                 630                 635                 640 


Gly His Tyr Ile Ala Tyr Cys Arg Asn Asn Leu Asn Asn Leu Trp Tyr 
                645                 650                 655     


Glu Phe Asp Asp Gln Ser Val Thr Glu Val Ser Glu Ser Thr Val Gln 
            660                 665                 670         


Asn Ala Glu Ala Tyr Val Leu Phe Tyr Arg Lys Ser Ser Glu Glu Ala 
        675                 680                 685             


Gln Lys Glu Arg Arg Arg Ile Ser Asn Leu Leu Asn Ile Met Glu Pro 
    690                 695                 700                 


Ser Leu Leu Gln Phe Tyr Ile Ser Arg Gln Trp Leu Asn Lys Phe Lys 
705                 710                 715                 720 


Thr Phe Ala Glu Pro Gly Pro Ile Ser Asn Asn Asp Phe Leu Cys Ile 
                725                 730                 735     


His Gly Gly Val Pro Pro Arg Lys Ala Gly Tyr Ile Glu Asp Leu Val 
            740                 745                 750         


Leu Met Leu Pro Gln Asn Ile Trp Asp Asn Leu Tyr Ser Arg Tyr Gly 
        755                 760                 765             


Gly Gly Pro Ala Val Asn His Leu Tyr Ile Cys His Thr Cys Gln Ile 
    770                 775                 780                 


Glu Ala Glu Lys Ile Glu Lys Arg Arg Lys Thr Glu Leu Glu Ile Phe 
785                 790                 795                 800 


Ile Arg Leu Asn Arg Ala Phe Gln Lys Glu Asp Ser Pro Ala Thr Phe 
                805                 810                 815     


Tyr Cys Ile Ser Met Gln Trp Phe Arg Glu Trp Glu Ser Phe Val Lys 
            820                 825                 830         


Gly Lys Asp Gly Asp Pro Pro Gly Pro Ile Asp Asn Thr Lys Ile Ala 
        835                 840                 845             


Val Thr Lys Cys Gly Asn Val Met Leu Arg Gln Gly Ala Asp Ser Gly 
    850                 855                 860                 


Gln Ile Ser Glu Glu Thr Trp Asn Phe Leu Gln Ser Ile Tyr Gly Gly 
865                 870                 875                 880 


Gly Pro Glu Val Ile Leu Arg Pro Pro Val Val His Val Asp Pro Asp 
                885                 890                 895     


Ile Leu Gln Ala Glu Glu Lys Ile Glu Val Glu Thr Arg Ser Leu 
            900                 905                 910     


<210>  3086
<211>  942
<212>  PRT
<213>  homo sapiens

<400>  3086

Met Thr Gly Ser Asn Ser His Ile Thr Ile Leu Thr Leu Lys Val Leu 
1               5                   10                  15      


Pro His Phe Glu Ser Leu Gly Lys Gln Glu Lys Ile Pro Asn Lys Met 
            20                  25                  30          


Ser Ala Phe Arg Asn His Cys Pro His Leu Asp Ser Val Gly Glu Ile 
        35                  40                  45              


Thr Lys Glu Asp Leu Ile Gln Lys Ser Leu Gly Thr Cys Gln Asp Cys 
    50                  55                  60                  


Lys Val Gln Gly Pro Asn Leu Trp Ala Cys Leu Glu Asn Arg Cys Ser 
65                  70                  75                  80  


Tyr Val Gly Cys Gly Glu Ser Gln Val Asp His Ser Thr Ile His Ser 
                85                  90                  95      


Gln Glu Thr Lys His Tyr Leu Thr Val Asn Leu Thr Thr Leu Arg Val 
            100                 105                 110         


Trp Cys Tyr Ala Cys Ser Lys Glu Val Phe Leu Asp Arg Lys Leu Gly 
        115                 120                 125             


Thr Gln Pro Ser Leu Pro His Val Arg Gln Pro His Gln Ile Gln Glu 
    130                 135                 140                 


Asn Ser Val Gln Asp Phe Lys Ile Pro Ser Asn Thr Thr Leu Lys Thr 
145                 150                 155                 160 


Pro Leu Val Ala Val Phe Asp Asp Leu Asp Ile Glu Ala Asp Glu Glu 
                165                 170                 175     


Asp Glu Leu Arg Ala Arg Gly Leu Thr Gly Leu Lys Asn Ile Gly Asn 
            180                 185                 190         


Thr Cys Tyr Met Asn Ala Ala Leu Gln Ala Leu Ser Asn Cys Pro Pro 
        195                 200                 205             


Leu Thr Gln Phe Phe Leu Asp Cys Gly Gly Leu Ala Arg Thr Asp Lys 
    210                 215                 220                 


Lys Pro Ala Ile Cys Lys Ser Tyr Leu Lys Leu Met Thr Glu Leu Trp 
225                 230                 235                 240 


His Lys Ser Arg Pro Gly Ser Val Val Pro Thr Thr Leu Phe Gln Gly 
                245                 250                 255     


Ile Lys Thr Val Asn Pro Thr Phe Arg Gly Tyr Ser Gln Gln Asp Ala 
            260                 265                 270         


Gln Glu Phe Leu Arg Cys Leu Met Asp Leu Leu His Glu Glu Leu Lys 
        275                 280                 285             


Glu Gln Val Met Glu Val Glu Glu Asp Pro Gln Thr Ile Thr Thr Glu 
    290                 295                 300                 


Glu Thr Met Glu Glu Asp Lys Ser Gln Ser Asp Val Asp Phe Gln Ser 
305                 310                 315                 320 


Cys Glu Ser Cys Ser Asn Ser Asp Arg Ala Glu Asn Glu Asn Gly Ser 
                325                 330                 335     


Arg Cys Phe Ser Glu Asp Asn Asn Glu Thr Thr Met Leu Ile Gln Asp 
            340                 345                 350         


Asp Glu Asn Asn Ser Glu Met Ser Lys Asp Trp Gln Lys Glu Lys Met 
        355                 360                 365             


Cys Asn Lys Ile Asn Lys Val Asn Ser Glu Gly Glu Phe Asp Lys Asp 
    370                 375                 380                 


Arg Asp Ser Ile Ser Glu Thr Val Asp Leu Asn Asn Gln Glu Thr Val 
385                 390                 395                 400 


Lys Val Gln Ile His Ser Arg Ala Ser Glu Tyr Ile Thr Asp Val His 
                405                 410                 415     


Ser Asn Asp Leu Ser Thr Pro Gln Ile Leu Pro Ser Asn Glu Gly Val 
            420                 425                 430         


Asn Pro Arg Leu Ser Ala Ser Pro Pro Lys Ser Gly Asn Leu Trp Pro 
        435                 440                 445             


Gly Leu Ala Pro Pro His Lys Lys Ala Gln Ser Ala Ser Pro Lys Arg 
    450                 455                 460                 


Lys Lys Gln His Lys Lys Tyr Arg Ser Val Ile Ser Asp Ile Phe Asp 
465                 470                 475                 480 


Gly Thr Ile Ile Ser Ser Val Gln Cys Leu Thr Cys Asp Arg Val Ser 
                485                 490                 495     


Val Thr Leu Glu Thr Phe Gln Asp Leu Ser Leu Pro Ile Pro Gly Lys 
            500                 505                 510         


Glu Asp Leu Ala Lys Leu His Ser Ser Ser His Pro Thr Ser Ile Val 
        515                 520                 525             


Lys Ala Gly Ser Cys Gly Glu Ala Tyr Ala Pro Gln Gly Trp Ile Ala 
    530                 535                 540                 


Phe Phe Met Glu Tyr Val Lys Arg Phe Val Val Ser Cys Val Pro Ser 
545                 550                 555                 560 


Trp Phe Trp Gly Pro Val Val Thr Leu Gln Asp Cys Leu Ala Ala Phe 
                565                 570                 575     


Phe Ala Arg Asp Glu Leu Lys Gly Asp Asn Met Tyr Ser Cys Glu Lys 
            580                 585                 590         


Cys Lys Lys Leu Arg Asn Gly Val Lys Phe Cys Lys Val Gln Asn Phe 
        595                 600                 605             


Pro Glu Ile Leu Cys Ile His Leu Lys Arg Phe Arg His Glu Leu Met 
    610                 615                 620                 


Phe Ser Thr Lys Ile Ser Thr His Val Ser Phe Pro Leu Glu Gly Leu 
625                 630                 635                 640 


Asp Leu Gln Pro Phe Leu Ala Lys Asp Ser Pro Ala Gln Ile Val Thr 
                645                 650                 655     


Tyr Asp Leu Leu Ser Val Ile Cys His His Gly Thr Ala Ser Ser Gly 
            660                 665                 670         


His Tyr Ile Ala Tyr Cys Arg Asn Asn Leu Asn Asn Leu Trp Tyr Glu 
        675                 680                 685             


Phe Asp Asp Gln Ser Val Thr Glu Val Ser Glu Ser Thr Val Gln Asn 
    690                 695                 700                 


Ala Glu Ala Tyr Val Leu Phe Tyr Arg Lys Ser Ser Glu Glu Ala Gln 
705                 710                 715                 720 


Lys Glu Arg Arg Arg Ile Ser Asn Leu Leu Asn Ile Met Glu Pro Ser 
                725                 730                 735     


Leu Leu Gln Phe Tyr Ile Ser Arg Gln Trp Leu Asn Lys Phe Lys Thr 
            740                 745                 750         


Phe Ala Glu Pro Gly Pro Ile Ser Asn Asn Asp Phe Leu Cys Ile His 
        755                 760                 765             


Gly Gly Val Pro Pro Arg Lys Ala Gly Tyr Ile Glu Asp Leu Val Leu 
    770                 775                 780                 


Met Leu Pro Gln Asn Ile Trp Asp Asn Leu Tyr Ser Arg Tyr Gly Gly 
785                 790                 795                 800 


Gly Pro Ala Val Asn His Leu Tyr Ile Cys His Thr Cys Gln Ile Glu 
                805                 810                 815     


Ala Glu Lys Ile Glu Lys Arg Arg Lys Thr Glu Leu Glu Ile Phe Ile 
            820                 825                 830         


Arg Leu Asn Arg Ala Phe Gln Lys Glu Asp Ser Pro Ala Thr Phe Tyr 
        835                 840                 845             


Cys Ile Ser Met Gln Trp Phe Arg Glu Trp Glu Ser Phe Val Lys Gly 
    850                 855                 860                 


Lys Asp Gly Asp Pro Pro Gly Pro Ile Asp Asn Thr Lys Ile Ala Val 
865                 870                 875                 880 


Thr Lys Cys Gly Asn Val Met Leu Arg Gln Gly Ala Asp Ser Gly Gln 
                885                 890                 895     


Ile Ser Glu Glu Thr Trp Asn Phe Leu Gln Ser Ile Tyr Gly Gly Gly 
            900                 905                 910         


Pro Glu Val Ile Leu Arg Pro Pro Val Val His Val Asp Pro Asp Ile 
        915                 920                 925             


Leu Gln Ala Glu Glu Lys Ile Glu Val Glu Thr Arg Ser Leu 
    930                 935                 940         


<210>  3087
<211>  526
<212>  PRT
<213>  homo sapiens

<400>  3087

Met Glu Thr Glu Ala Ile Asp Gly Tyr Ile Thr Cys Asp Asn Glu Leu 
1               5                   10                  15      


Ser Pro Glu Arg Glu His Ser Asn Met Ala Ile Asp Leu Thr Ser Ser 
            20                  25                  30          


Thr Pro Asn Gly Gln His Ala Ser Pro Ser His Met Thr Ser Thr Asn 
        35                  40                  45              


Ser Val Lys Leu Glu Met Gln Ser Asp Glu Glu Cys Asp Arg Lys Pro 
    50                  55                  60                  


Leu Ser Arg Glu Asp Glu Ile Arg Gly His Asp Glu Gly Ser Ser Leu 
65                  70                  75                  80  


Glu Glu Pro Leu Ile Glu Ser Ser Glu Val Ala Asp Asn Arg Lys Val 
                85                  90                  95      


Gln Glu Leu Gln Gly Glu Gly Gly Ile Arg Leu Pro Asn Gly Lys Leu 
            100                 105                 110         


Lys Cys Asp Val Cys Gly Met Val Cys Ile Gly Pro Asn Val Leu Met 
        115                 120                 125             


Val His Lys Arg Ser His Thr Gly Glu Arg Pro Phe His Cys Asn Gln 
    130                 135                 140                 


Cys Gly Ala Ser Phe Thr Gln Lys Gly Asn Leu Leu Arg His Ile Lys 
145                 150                 155                 160 


Leu His Ser Gly Glu Lys Pro Phe Lys Cys Pro Phe Cys Ser Tyr Ala 
                165                 170                 175     


Cys Arg Arg Arg Asp Ala Leu Thr Gly His Leu Arg Thr His Ser Val 
            180                 185                 190         


Gly Lys Pro His Lys Cys Asn Tyr Cys Gly Arg Ser Tyr Lys Gln Arg 
        195                 200                 205             


Ser Ser Leu Glu Glu His Lys Glu Arg Cys His Asn Tyr Leu Gln Asn 
    210                 215                 220                 


Val Ser Met Glu Ala Ala Gly Gln Val Met Ser His His Val Pro Pro 
225                 230                 235                 240 


Met Glu Asp Cys Lys Glu Gln Glu Pro Ile Met Asp Asn Asn Ile Ser 
                245                 250                 255     


Leu Val Pro Phe Glu Arg Pro Ala Val Ile Glu Lys Leu Thr Gly Asn 
            260                 265                 270         


Met Gly Lys Arg Lys Ser Ser Thr Pro Gln Lys Phe Val Gly Glu Lys 
        275                 280                 285             


Leu Met Arg Phe Ser Tyr Pro Asp Ile His Phe Asp Met Asn Leu Thr 
    290                 295                 300                 


Tyr Glu Lys Glu Ala Glu Leu Met Gln Ser His Met Met Asp Gln Ala 
305                 310                 315                 320 


Ile Asn Asn Ala Ile Thr Tyr Leu Gly Ala Glu Ala Leu His Pro Leu 
                325                 330                 335     


Met Gln His Pro Pro Ser Thr Ile Ala Glu Val Ala Pro Val Ile Ser 
            340                 345                 350         


Ser Ala Tyr Ser Gln Val Tyr His Pro Asn Arg Ile Glu Arg Pro Ile 
        355                 360                 365             


Ser Arg Glu Thr Ala Asp Ser His Glu Asn Asn Met Asp Gly Pro Ile 
    370                 375                 380                 


Ser Leu Ile Arg Pro Lys Ser Arg Pro Gln Glu Arg Glu Ala Ser Pro 
385                 390                 395                 400 


Ser Asn Ser Cys Leu Asp Ser Thr Asp Ser Glu Ser Ser His Asp Asp 
                405                 410                 415     


His Gln Ser Tyr Gln Gly His Pro Ala Leu Asn Pro Lys Arg Lys Gln 
            420                 425                 430         


Ser Pro Ala Tyr Met Lys Glu Asp Val Lys Ala Leu Asp Thr Thr Lys 
        435                 440                 445             


Ala Pro Lys Gly Ser Leu Lys Asp Ile Tyr Lys Val Phe Asn Gly Glu 
    450                 455                 460                 


Gly Glu Gln Ile Arg Ala Phe Lys Cys Glu His Cys Arg Val Leu Phe 
465                 470                 475                 480 


Leu Asp His Val Met Tyr Thr Ile His Met Gly Cys His Gly Tyr Arg 
                485                 490                 495     


Asp Pro Leu Glu Cys Asn Ile Cys Gly Tyr Arg Ser Gln Asp Arg Tyr 
            500                 505                 510         


Glu Phe Ser Ser His Ile Val Arg Gly Glu His Thr Phe His 
        515                 520                 525     


<210>  3088
<211>  1976
<212>  PRT
<213>  homo sapiens

<400>  3088

Met Gly Val Leu Lys Val Trp Leu Gly Leu Ala Leu Ala Leu Ala Glu 
1               5                   10                  15      


Phe Ala Val Leu Pro His His Ser Glu Gly Ala Cys Val Tyr Gln Asp 
            20                  25                  30          


Ser Leu Leu Ala Asp Ala Thr Ile Trp Lys Pro Asp Ser Cys Gln Ser 
        35                  40                  45              


Cys Arg Cys His Gly Asp Ile Val Ile Cys Lys Pro Ala Val Cys Arg 
    50                  55                  60                  


Asn Pro Gln Cys Ala Phe Glu Lys Gly Glu Val Leu Gln Ile Ala Ala 
65                  70                  75                  80  


Asn Gln Cys Cys Pro Glu Cys Val Leu Arg Thr Pro Gly Ser Cys His 
                85                  90                  95      


His Glu Lys Lys Ile His Glu His Gly Thr Glu Trp Ala Ser Ser Pro 
            100                 105                 110         


Cys Ser Val Cys Ser Cys Asn His Gly Glu Val Arg Cys Thr Pro Gln 
        115                 120                 125             


Pro Cys Pro Pro Leu Ser Cys Gly His Gln Glu Leu Ala Phe Ile Pro 
    130                 135                 140                 


Glu Gly Ser Cys Cys Pro Val Cys Val Gly Leu Gly Lys Pro Cys Ser 
145                 150                 155                 160 


Tyr Glu Gly His Val Phe Gln Asp Gly Glu Asp Trp Arg Leu Ser Arg 
                165                 170                 175     


Cys Ala Lys Cys Leu Cys Arg Asn Gly Val Ala Gln Cys Phe Thr Ala 
            180                 185                 190         


Gln Cys Gln Pro Leu Phe Cys Asn Gln Asp Glu Thr Val Val Arg Val 
        195                 200                 205             


Pro Gly Lys Cys Cys Pro Gln Cys Ser Ala Arg Ser Cys Ser Ala Ala 
    210                 215                 220                 


Gly Gln Val Tyr Glu His Gly Glu Gln Trp Ser Glu Asn Ala Cys Thr 
225                 230                 235                 240 


Thr Cys Ile Cys Asp Arg Gly Glu Val Arg Cys His Lys Gln Ala Cys 
                245                 250                 255     


Leu Pro Leu Arg Cys Gly Lys Gly Gln Ser Arg Ala Arg Arg His Gly 
            260                 265                 270         


Gln Cys Cys Glu Glu Cys Val Ser Pro Ala Gly Ser Cys Ser Tyr Asp 
        275                 280                 285             


Gly Val Val Arg Tyr Gln Asp Glu Met Trp Lys Gly Ser Ala Cys Glu 
    290                 295                 300                 


Phe Cys Met Cys Asp His Gly Gln Val Thr Cys Gln Thr Gly Glu Cys 
305                 310                 315                 320 


Ala Lys Val Glu Cys Ala Arg Asp Glu Glu Leu Ile His Leu Asp Gly 
                325                 330                 335     


Lys Cys Cys Pro Glu Cys Ile Ser Arg Asn Gly Tyr Cys Val Tyr Glu 
            340                 345                 350         


Glu Thr Gly Glu Phe Met Ser Ser Asn Ala Ser Glu Val Lys Arg Ile 
        355                 360                 365             


Pro Glu Gly Glu Lys Trp Glu Asp Gly Pro Cys Lys Val Cys Glu Cys 
    370                 375                 380                 


Arg Gly Ala Gln Val Thr Cys Tyr Glu Pro Ser Cys Pro Pro Cys Pro 
385                 390                 395                 400 


Val Gly Thr Leu Ala Leu Glu Val Lys Gly Gln Cys Cys Pro Asp Cys 
                405                 410                 415     


Thr Ser Val His Cys His Pro Asp Cys Leu Thr Cys Ser Gln Ser Pro 
            420                 425                 430         


Asp His Cys Asp Leu Cys Gln Asp Pro Thr Lys Leu Leu Gln Asn Gly 
        435                 440                 445             


Trp Cys Val His Ser Cys Gly Leu Gly Phe Tyr Gln Ala Gly Ser Leu 
    450                 455                 460                 


Cys Leu Ala Cys Gln Pro Gln Cys Ser Thr Cys Thr Ser Gly Leu Glu 
465                 470                 475                 480 


Cys Ser Ser Cys Gln Pro Pro Leu Leu Met Arg His Gly Gln Cys Val 
                485                 490                 495     


Pro Thr Cys Gly Asp Gly Phe Tyr Gln Asp Arg His Ser Cys Ala Val 
            500                 505                 510         


Cys His Glu Ser Cys Ala Gly Cys Trp Gly Pro Thr Glu Lys His Cys 
        515                 520                 525             


Leu Ala Cys Arg Asp Pro Leu His Val Leu Arg Asp Gly Gly Cys Glu 
    530                 535                 540                 


Ser Ser Cys Gly Lys Gly Phe Tyr Asn Arg Gln Gly Thr Cys Ser Ala 
545                 550                 555                 560 


Cys Asp Gln Ser Cys Asp Ser Cys Gly Pro Ser Ser Pro Arg Cys Leu 
                565                 570                 575     


Thr Cys Thr Glu Lys Thr Val Leu His Asp Gly Lys Cys Met Ser Glu 
            580                 585                 590         


Cys Pro Gly Gly Tyr Tyr Ala Asp Ala Thr Gly Arg Cys Lys Val Cys 
        595                 600                 605             


His Asn Ser Cys Ala Ser Cys Ser Gly Pro Thr Pro Ser His Cys Thr 
    610                 615                 620                 


Ala Cys Ser Pro Pro Lys Ala Leu Arg Gln Gly His Cys Leu Pro Arg 
625                 630                 635                 640 


Cys Gly Glu Gly Phe Tyr Ser Asp His Gly Val Cys Lys Ala Cys His 
                645                 650                 655     


Ser Ser Cys Leu Ala Cys Met Gly Pro Ala Pro Ser His Cys Thr Gly 
            660                 665                 670         


Cys Lys Lys Pro Glu Glu Gly Leu Gln Val Glu Gln Leu Ser Asp Val 
        675                 680                 685             


Gly Ile Pro Ser Gly Glu Cys Leu Ala Gln Cys Arg Ala His Phe Tyr 
    690                 695                 700                 


Leu Glu Ser Thr Gly Ile Cys Glu Ala Cys His Gln Ser Cys Phe Arg 
705                 710                 715                 720 


Cys Ala Gly Lys Ser Pro His Asn Cys Thr Asp Cys Gly Pro Ser His 
                725                 730                 735     


Val Leu Leu Asp Gly Gln Cys Leu Ser Gln Cys Pro Asp Gly Tyr Phe 
            740                 745                 750         


His Gln Glu Gly Ser Cys Thr Glu Cys His Pro Thr Cys Arg Gln Cys 
        755                 760                 765             


His Gly Pro Leu Glu Ser Asp Cys Ile Ser Cys Tyr Pro His Ile Ser 
    770                 775                 780                 


Leu Thr Asn Gly Asn Cys Arg Thr Ser Cys Arg Glu Glu Gln Phe Leu 
785                 790                 795                 800 


Asn Leu Val Gly Tyr Cys Ala Asp Cys His His Leu Cys Gln His Cys 
                805                 810                 815     


Ala Ala Asp Leu His Asn Thr Gly Ser Ile Cys Leu Arg Cys Gln Asn 
            820                 825                 830         


Ala His Tyr Leu Leu Leu Gly Asp His Cys Val Pro Asp Cys Pro Ser 
        835                 840                 845             


Gly Tyr Tyr Ala Glu Arg Gly Ala Cys Lys Lys Cys His Ser Ser Cys 
    850                 855                 860                 


Arg Thr Cys Gln Gly Arg Gly Pro Phe Ser Cys Ser Ser Cys Asp Thr 
865                 870                 875                 880 


Asn Leu Val Leu Ser His Thr Gly Thr Cys Ser Thr Thr Cys Phe Pro 
                885                 890                 895     


Gly His Tyr Leu Asp Asp Asn His Val Cys Gln Pro Cys Asn Thr His 
            900                 905                 910         


Cys Gly Ser Cys Asp Ser Gln Ala Ser Cys Thr Ser Cys Arg Asp Pro 
        915                 920                 925             


Asn Lys Val Leu Leu Phe Gly Glu Cys Gln Tyr Glu Ser Cys Ala Pro 
    930                 935                 940                 


Gln Tyr Tyr Leu Asp Phe Ser Thr Asn Thr Cys Lys Glu Cys Asp Trp 
945                 950                 955                 960 


Ser Cys Ser Ala Cys Ser Gly Pro Leu Lys Thr Asp Cys Leu Gln Cys 
                965                 970                 975     


Met Asp Gly Tyr Val Leu Gln Asp Gly Ala Cys Val Glu Gln Cys Leu 
            980                 985                 990         


Ser Ser Phe Tyr Gln Asp Ser Gly  Leu Cys Lys Asn Cys  Asp Ser Tyr 
        995                 1000                 1005             


Cys Leu  Gln Cys Gln Gly Pro  His Glu Cys Thr Arg  Cys Lys Gly 
    1010                 1015                 1020             


Pro Phe  Leu Leu Leu Glu Ala  Gln Cys Val Gln Glu  Cys Gly Lys 
    1025                 1030                 1035             


Gly Tyr  Phe Ala Asp His Ala  Lys His Lys Cys Thr  Ala Cys Pro 
    1040                 1045                 1050             


Gln Gly  Cys Leu Gln Cys Ser  His Arg Asp Arg Cys  His Leu Cys 
    1055                 1060                 1065             


Asp His  Gly Phe Phe Leu Lys  Ser Gly Leu Cys Val  Tyr Asn Cys 
    1070                 1075                 1080             


Val Pro  Gly Phe Ser Val His  Thr Ser Asn Glu Thr  Cys Ser Gly 
    1085                 1090                 1095             


Lys Ile  His Thr Pro Ser Leu  His Val Asn Gly Ser  Leu Ile Leu 
    1100                 1105                 1110             


Pro Ile  Gly Ser Ile Lys Pro  Leu Asp Phe Ser Leu  Leu Asn Val 
    1115                 1120                 1125             


Gln Asp  Gln Glu Gly Arg Val  Glu Asp Leu Leu Phe  His Val Val 
    1130                 1135                 1140             


Ser Thr  Pro Thr Asn Gly Gln  Leu Val Leu Ser Arg  Asn Gly Lys 
    1145                 1150                 1155             


Glu Val  Gln Leu Asp Lys Ala  Gly Arg Phe Ser Trp  Lys Asp Val 
    1160                 1165                 1170             


Asn Glu  Lys Lys Val Arg Phe  Val His Ser Lys Glu  Lys Leu Arg 
    1175                 1180                 1185             


Lys Gly  Tyr Leu Phe Leu Lys  Ile Ser Asp Gln Gln  Phe Phe Ser 
    1190                 1195                 1200             


Glu Pro  Gln Leu Ile Asn Ile  Gln Ala Phe Ser Thr  Gln Ala Pro 
    1205                 1210                 1215             


Tyr Val  Leu Arg Asn Glu Val  Leu His Ile Ser Arg  Gly Glu Arg 
    1220                 1225                 1230             


Ala Thr  Ile Thr Thr Gln Met  Leu Asp Ile Arg Asp  Asp Asp Asn 
    1235                 1240                 1245             


Pro Gln  Asp Val Val Ile Glu  Ile Ile Asp Pro Pro  Leu His Gly 
    1250                 1255                 1260             


Gln Leu  Leu Gln Thr Leu Gln  Ser Pro Ala Thr Pro  Ile Tyr Gln 
    1265                 1270                 1275             


Phe Gln  Leu Asp Glu Leu Ser  Arg Gly Leu Leu His  Tyr Ala His 
    1280                 1285                 1290             


Asp Gly  Ser Asp Ser Thr Ser  Asp Val Ala Val Leu  Gln Ala Asn 
    1295                 1300                 1305             


Asp Gly  His Ser Phe His Asn  Ile Leu Phe Gln Val  Lys Thr Val 
    1310                 1315                 1320             


Pro Gln  Asn Asp Arg Gly Leu  Gln Leu Val Ala Asn  Ser Met Val 
    1325                 1330                 1335             


Trp Val  Pro Glu Gly Gly Met  Leu Gln Ile Thr Asn  Arg Ile Leu 
    1340                 1345                 1350             


Gln Ala  Glu Ala Pro Gly Ala  Ser Ala Glu Glu Ile  Ile Tyr Lys 
    1355                 1360                 1365             


Ile Thr  Gln Asp Tyr Pro Gln  Phe Gly Glu Val Val  Leu Leu Val 
    1370                 1375                 1380             


Asn Met  Pro Ala Asp Ser Pro  Ala Asp Glu Gly Gln  His Leu Pro 
    1385                 1390                 1395             


Asp Gly  Arg Thr Ala Thr Pro  Thr Ser Thr Phe Thr  Gln Gln Asp 
    1400                 1405                 1410             


Ile Asn  Glu Gly Ile Val Trp  Tyr Arg His Ser Gly  Ala Pro Ala 
    1415                 1420                 1425             


Gln Ser  Asp Ser Phe Arg Phe  Glu Val Ser Ser Ala  Ser Asn Ala 
    1430                 1435                 1440             


Gln Thr  Arg Leu Glu Ser His  Met Phe Asn Ile Ala  Ile Leu Pro 
    1445                 1450                 1455             


Gln Thr  Pro Glu Ala Pro Lys  Val Ser Leu Glu Ala  Ser Leu His 
    1460                 1465                 1470             


Met Thr  Ala Arg Glu Asp Gly  Leu Thr Val Ile Gln  Pro His Ser 
    1475                 1480                 1485             


Leu Ser  Phe Ile Asn Ser Glu  Lys Pro Ser Gly Lys  Ile Val Tyr 
    1490                 1495                 1500             


Asn Ile  Thr Leu Pro Leu His  Pro Asn Gln Gly Ile  Ile Glu His 
    1505                 1510                 1515             


Arg Asp  His Pro His Ser Pro  Ile Arg Tyr Phe Thr  Gln Glu Asp 
    1520                 1525                 1530             


Ile Asn  Gln Gly Lys Val Met  Tyr Arg Pro Pro Pro  Ala Ala Pro 
    1535                 1540                 1545             


His Leu  Gln Glu Leu Met Ala  Phe Ser Phe Ala Gly  Leu Pro Glu 
    1550                 1555                 1560             


Ser Val  Lys Phe His Phe Thr  Val Ser Asp Gly Glu  His Thr Ser 
    1565                 1570                 1575             


Pro Glu  Met Val Leu Thr Ile  His Leu Leu Pro Ser  Asp Gln Gln 
    1580                 1585                 1590             


Leu Pro  Val Phe Gln Val Thr  Ala Pro Arg Leu Ala  Val Ser Pro 
    1595                 1600                 1605             


Gly Gly  Ser Thr Ser Val Gly  Leu Gln Val Val Val  Arg Asp Ala 
    1610                 1615                 1620             


Glu Thr  Ala Pro Lys Glu Leu  Phe Phe Glu Leu Arg  Arg Pro Pro 
    1625                 1630                 1635             


Gln His  Gly Val Leu Leu Lys  His Thr Ala Glu Phe  Arg Arg Pro 
    1640                 1645                 1650             


Met Ala  Thr Gly Asp Thr Phe  Thr Tyr Glu Asp Val  Glu Lys Asn 
    1655                 1660                 1665             


Ala Leu  Gln Tyr Ile His Asp  Gly Ser Ser Thr Arg  Glu Asp Ser 
    1670                 1675                 1680             


Met Glu  Ile Ser Val Thr Asp  Gly Leu Thr Val Thr  Met Leu Glu 
    1685                 1690                 1695             


Val Arg  Val Glu Val Ser Leu  Ser Glu Asp Arg Gly  Pro Arg Leu 
    1700                 1705                 1710             


Ala Ala  Gly Ser Ser Leu Ser  Ile Thr Val Ala Ser  Lys Ser Thr 
    1715                 1720                 1725             


Ala Ile  Ile Thr Arg Ser His  Leu Ala Tyr Val Asp  Asp Ser Ser 
    1730                 1735                 1740             


Pro Asp  Pro Glu Ile Trp Ile  Gln Leu Asn Tyr Leu  Pro Ser Tyr 
    1745                 1750                 1755             


Gly Thr  Leu Leu Arg Ile Ser  Gly Ser Glu Val Glu  Glu Leu Ser 
    1760                 1765                 1770             


Glu Val  Ser Asn Phe Thr Met  Glu Asp Ile Asn Asn  Lys Lys Ile 
    1775                 1780                 1785             


Arg Tyr  Ser Ala Val Phe Glu  Thr Asp Gly His Leu  Val Thr Asp 
    1790                 1795                 1800             


Ser Phe  Tyr Phe Ser Val Ser  Asp Met Asp His Asn  His Leu Asp 
    1805                 1810                 1815             


Asn Gln  Ile Phe Thr Ile Met  Ile Thr Pro Ala Glu  Asn Pro Pro 
    1820                 1825                 1830             


Pro Val  Ile Ala Phe Ala Asp  Leu Ile Thr Val Asp  Glu Gly Gly 
    1835                 1840                 1845             


Arg Ala  Pro Leu Ser Phe His  His Phe Phe Ala Thr  Asp Asp Asp 
    1850                 1855                 1860             


Asp Asn  Leu Gln Arg Asp Ala  Ile Ile Lys Leu Ser  Ala Leu Pro 
    1865                 1870                 1875             


Lys Tyr  Gly Cys Ile Glu Asn  Thr Gly Thr Gly Asp  Arg Phe Gly 
    1880                 1885                 1890             


Pro Glu  Thr Ala Ser Asp Leu  Glu Ala Ser Phe Pro  Ile Gln Asp 
    1895                 1900                 1905             


Val Leu  Glu Asn Tyr Ile Tyr  Tyr Phe Gln Ser Val  His Glu Ser 
    1910                 1915                 1920             


Ile Glu  Pro Thr His Asp Ile  Phe Ser Phe Tyr Val  Ser Asp Gly 
    1925                 1930                 1935             


Thr Ser  Arg Ser Glu Ile His  Ser Ile Asn Ile Thr  Ile Glu Val 
    1940                 1945                 1950             


Lys Thr  Leu Glu Val Gly Lys  Val Glu Pro Leu Thr  Thr Ile Phe 
    1955                 1960                 1965             


His Thr  Ile Arg Glu Leu Ser  Leu 
    1970                 1975     


<210>  3089
<211>  349
<212>  PRT
<213>  homo sapiens

<400>  3089

Met Pro Val Glu Arg Met Arg Met Arg Pro Trp Leu Glu Glu Gln Ile 
1               5                   10                  15      


Asn Ser Asn Thr Ile Pro Gly Leu Lys Trp Leu Asn Lys Glu Lys Lys 
            20                  25                  30          


Ile Phe Gln Ile Pro Trp Met His Ala Ala Arg His Gly Trp Asp Val 
        35                  40                  45              


Glu Lys Asp Ala Pro Leu Phe Arg Asn Trp Ala Ile His Thr Gly Lys 
    50                  55                  60                  


His Gln Pro Gly Val Asp Lys Pro Asp Pro Lys Thr Trp Lys Ala Asn 
65                  70                  75                  80  


Phe Arg Cys Ala Met Asn Ser Leu Pro Asp Ile Glu Glu Val Lys Asp 
                85                  90                  95      


Lys Ser Ile Lys Lys Gly Asn Asn Ala Phe Arg Val Tyr Arg Met Leu 
            100                 105                 110         


Pro Leu Ser Glu Arg Pro Ser Lys Lys Gly Lys Lys Pro Lys Thr Glu 
        115                 120                 125             


Lys Glu Asp Lys Val Lys His Ile Lys Gln Glu Pro Val Glu Ser Ser 
    130                 135                 140                 


Leu Gly Leu Ser Asn Gly Val Ser Asp Leu Ser Pro Glu Tyr Ala Val 
145                 150                 155                 160 


Leu Thr Ser Thr Ile Lys Asn Glu Val Asp Ser Thr Val Asn Ile Ile 
                165                 170                 175     


Val Val Gly Gln Ser His Leu Asp Ser Asn Ile Glu Asn Gln Glu Ile 
            180                 185                 190         


Val Thr Asn Pro Pro Asp Ile Cys Gln Val Val Glu Val Thr Thr Glu 
        195                 200                 205             


Ser Asp Glu Gln Pro Val Ser Met Ser Glu Leu Tyr Pro Leu Gln Ile 
    210                 215                 220                 


Ser Pro Val Ser Ser Tyr Ala Glu Ser Glu Thr Thr Asp Ser Val Pro 
225                 230                 235                 240 


Ser Asp Glu Glu Ser Ala Glu Gly Arg Pro His Trp Arg Lys Arg Asn 
                245                 250                 255     


Ile Glu Gly Lys Gln Tyr Leu Ser Asn Met Gly Thr Arg Gly Ser Tyr 
            260                 265                 270         


Leu Leu Pro Gly Met Ala Ser Phe Val Thr Ser Asn Lys Pro Asp Leu 
        275                 280                 285             


Gln Val Thr Ile Lys Glu Glu Ser Asn Pro Val Pro Tyr Asn Ser Ser 
    290                 295                 300                 


Trp Pro Pro Phe Gln Asp Leu Pro Leu Ser Ser Ser Met Thr Pro Ala 
305                 310                 315                 320 


Ser Ser Ser Ser Arg Pro Asp Arg Glu Thr Arg Ala Ser Val Ile Lys 
                325                 330                 335     


Lys Thr Ser Asp Ile Thr Gln Ala Arg Val Lys Ser Cys 
            340                 345                 


<210>  3090
<211>  1233
<212>  PRT
<213>  homo sapiens

<400>  3090

Met Ser Ile Asp His Leu Lys Gln Lys Ile Pro Pro Ala Leu Phe Tyr 
1               5                   10                  15      


Lys Glu Thr Tyr Leu Gly Pro Asn Glu Val Leu Lys Asn Gly Met Tyr 
            20                  25                  30          


Cys Ser Leu Tyr Glu Val Val Glu Lys Thr Arg Ile Gly Ser Asn Met 
        35                  40                  45              


Glu Ser Leu Leu Gln Lys Leu Asp Arg Glu Lys Leu Val Leu Val Lys 
    50                  55                  60                  


Pro Leu Gly Asp Arg Gly Tyr Leu Phe Leu Leu Ser Pro Tyr Gln Met 
65                  70                  75                  80  


Val Pro Pro Tyr Glu Tyr Gln Thr Ala Lys Ser Arg Val Leu His Ala 
                85                  90                  95      


Leu Phe Leu Phe Gln Glu Pro Arg Ser Ile Val Thr Ser Gln Lys Gly 
            100                 105                 110         


Ser Thr Asn Ala Ala Pro Gln Glu Arg His Glu Ser Met Pro Asp Val 
        115                 120                 125             


Leu Lys Ile Ala Gln Phe Leu Gln Phe Ser Leu Ile Gln Cys Arg Lys 
    130                 135                 140                 


Glu Phe Lys Asn Ile Ser Ala Ile Asn Phe His Ser Val Val Glu Lys 
145                 150                 155                 160 


Tyr Val Ser Glu Phe Phe Lys Arg Gly Phe Gly Ser Gly Lys Arg Glu 
                165                 170                 175     


Phe Ile Met Phe Pro Tyr Asp Ser Arg Leu Asp Asp Lys Lys Phe Leu 
            180                 185                 190         


Tyr Ser Ala Pro Arg Asn Lys Ser His Ile Asp Thr Cys Leu His Ala 
        195                 200                 205             


Tyr Ile Phe Arg Pro Glu Val Tyr Gln Leu Pro Ile Cys Lys Leu Lys 
    210                 215                 220                 


Glu Leu Phe Glu Glu Asn Arg Lys Leu Gln Gln Phe Ser Pro Leu Ser 
225                 230                 235                 240 


Asp Tyr Glu Gly Gln Glu Glu Glu Met Asn Gly Thr Lys Met Lys Phe 
                245                 250                 255     


Gly Lys Arg Asn Asn Ser Arg Gly Glu Ala Ile Ile Ser Gly Lys Gln 
            260                 265                 270         


Arg Ser Ser His Ser Leu Asp Tyr Asp Lys Asp Arg Val Lys Glu Leu 
        275                 280                 285             


Ile Asn Leu Ile Gln Cys Arg Lys Lys Ser Val Gly Gly Asp Ser Asp 
    290                 295                 300                 


Thr Glu Asp Met Arg Ser Lys Thr Val Leu Lys Arg Lys Leu Glu Asp 
305                 310                 315                 320 


Leu Pro Glu Asn Met Arg Lys Leu Ala Lys Thr Ser Asn Leu Ser Glu 
                325                 330                 335     


Asn Cys His Leu Tyr Glu Glu Ser Pro Gln Pro Ile Gly Ser Leu Gly 
            340                 345                 350         


His Asp Ala Asp Leu Arg Arg Gln Gln Gln Asp Thr Cys Asn Ser Gly 
        355                 360                 365             


Ile Ala Asp Ile His Arg Leu Phe Asn Trp Leu Ser Glu Thr Leu Ala 
    370                 375                 380                 


Asn Ala Arg His Ser Asp Ala Ser Leu Thr Asp Thr Val Asn Lys Ala 
385                 390                 395                 400 


Leu Gly Leu Ser Thr Asp Asp Ala Tyr Glu Glu Leu Arg Gln Lys His 
                405                 410                 415     


Glu Tyr Glu Leu Asn Ser Thr Pro Asp Lys Lys Asp Tyr Glu Gln Pro 
            420                 425                 430         


Thr Cys Ala Lys Val Glu Asn Ala Gln Phe Lys Gly Thr Gln Ser Leu 
        435                 440                 445             


Leu Leu Glu Val Asp Ala Thr Ser Lys Tyr Ser Val Ala Ile Ser Thr 
    450                 455                 460                 


Ser Glu Val Gly Thr Asp His Lys Leu His Leu Lys Glu Asp Pro Asn 
465                 470                 475                 480 


Leu Ile Ser Val Asn Asn Phe Glu Asp Cys Ser Leu Cys Pro Ser Val 
                485                 490                 495     


Pro Ile Glu His Gly Phe Arg Arg Gln Gln Ser Lys Ser Asn Asn Val 
            500                 505                 510         


Glu Glu Thr Glu Ile His Trp Lys Leu Ile Pro Ile Thr Gly Gly Asn 
        515                 520                 525             


Ala Arg Ser Pro Glu Asp Gln Leu Gly Lys His Gly Glu Lys Gln Thr 
    530                 535                 540                 


Pro Asp Thr Leu Lys Gly Thr Thr Glu Asp Asp Val Leu Thr Gly Gln 
545                 550                 555                 560 


Val Glu Glu Gln Cys Val Pro Ala Ala Glu Ala Glu Pro Pro Ala Val 
                565                 570                 575     


Ser Glu Thr Thr Glu Arg Thr Val Leu Gly Glu Tyr Asn Leu Phe Ser 
            580                 585                 590         


Arg Lys Ile Glu Glu Ile Leu Lys Gln Lys Asn Val Ser Tyr Val Ser 
        595                 600                 605             


Thr Val Ser Thr Pro Ile Phe Ser Thr Gln Glu Lys Met Lys Arg Leu 
    610                 615                 620                 


Ser Glu Phe Ile Tyr Ser Lys Thr Ser Lys Ala Gly Val Gln Glu Phe 
625                 630                 635                 640 


Val Asp Gly Leu His Glu Lys Leu Asn Thr Ile Ile Ile Lys Ala Ser 
                645                 650                 655     


Ala Lys Gly Gly Asn Leu Pro Pro Val Ser Pro Asn Asp Ser Gly Ala 
            660                 665                 670         


Lys Ile Ala Ser Asn Pro Leu Glu Arg His Val Ile Pro Val Ser Ser 
        675                 680                 685             


Ser Asp Phe Asn Asn Lys His Leu Leu Glu Pro Leu Cys Ser Asp Pro 
    690                 695                 700                 


Leu Lys Asp Thr Asn Ser Asp Glu Gln His Ser Thr Ser Ala Leu Thr 
705                 710                 715                 720 


Glu Val Glu Met Asn Gln Pro Gln His Ala Thr Glu Leu Met Val Thr 
                725                 730                 735     


Ser Asp His Ile Val Pro Gly Asp Met Ala Arg Glu Pro Val Glu Glu 
            740                 745                 750         


Thr Thr Lys Ser Pro Ser Asp Val Asn Ile Ser Ala Gln Pro Ala Leu 
        755                 760                 765             


Ser Asn Phe Ile Ser Gln Leu Glu Pro Glu Val Phe Asn Ser Leu Val 
    770                 775                 780                 


Lys Ile Met Lys Asp Val Gln Lys Asn Thr Val Lys Phe Tyr Ile His 
785                 790                 795                 800 


Glu Glu Glu Glu Ser Val Leu Cys Lys Glu Ile Lys Glu Tyr Leu Ile 
                805                 810                 815     


Lys Leu Gly Asn Thr Glu Cys His Pro Glu Gln Phe Leu Glu Arg Arg 
            820                 825                 830         


Ser Lys Leu Asp Lys Leu Leu Ile Ile Ile Gln Asn Glu Asp Ile Ala 
        835                 840                 845             


Gly Phe Ile His Lys Ile Pro Gly Leu Val Thr Leu Lys Lys Leu Pro 
    850                 855                 860                 


Cys Val Ser Phe Ala Gly Val Asp Ser Leu Asp Asp Val Lys Asn His 
865                 870                 875                 880 


Thr Tyr Asn Glu Leu Phe Val Ser Gly Gly Phe Ile Val Ser Asp Glu 
                885                 890                 895     


Ser Ile Leu Asn Pro Glu Val Val Thr Val Glu Asn Leu Lys Asn Phe 
            900                 905                 910         


Leu Thr Phe Leu Glu Glu Leu Ser Thr Pro Glu Gly Lys Trp Gln Trp 
        915                 920                 925             


Lys Val His Cys Lys Phe Gln Lys Lys Leu Lys Glu Leu Gly Arg Leu 
    930                 935                 940                 


Asn Ala Lys Ala Leu Ser Leu Leu Thr Leu Leu Asn Val Tyr Gln Lys 
945                 950                 955                 960 


Lys His Leu Val Glu Ile Leu Ser Tyr His Asn Cys Asp Ser Gln Thr 
                965                 970                 975     


Arg Asn Ala Pro Glu Leu Asp Cys Leu Ile Arg Leu Gln Ala Gln Asn 
            980                 985                 990         


Ile Gln Gln Arg His Ile Val Phe  Leu Thr Glu Lys Asn  Ile Lys Met 
        995                 1000                 1005             


Leu Ser  Ser Tyr Thr Asp Asn  Gly Ile Val Val Ala  Thr Ala Glu 
    1010                 1015                 1020             


Asp Phe  Met Gln Asn Phe Lys  Asn Leu Val Gly Tyr  His Asn Ser 
    1025                 1030                 1035             


Ile Thr  Glu Glu Asn Leu Pro  Gln Leu Gly Ala Asn  Glu Asn Leu 
    1040                 1045                 1050             


Glu Ser  Gln Ser Ala Leu Leu  Glu Asn Asp Glu Lys  Asp Glu Glu 
    1055                 1060                 1065             


Asp Met  Ser Leu Asp Ser Gly  Asp Glu Ile Ser His  Ile Glu Val 
    1070                 1075                 1080             


Cys Ser  Asn Phe His Ser Glu  Ile Trp Glu Lys Glu  Thr Lys Gly 
    1085                 1090                 1095             


Ser Arg  Gly Thr Asp Gln Lys  Lys Asn Thr Gln Ile  Glu Leu Gln 
    1100                 1105                 1110             


Ser Ser  Pro Asp Val Gln Asn  Ser Leu Leu Glu Asp  Lys Thr Tyr 
    1115                 1120                 1125             


Leu Asp  Ser Glu Glu Arg Thr  Ser Ile Asp Ile Val  Cys Ser Glu 
    1130                 1135                 1140             


Gly Glu  Asn Ser Asn Ser Thr  Glu Gln Asp Ser Tyr  Ser Asn Phe 
    1145                 1150                 1155             


Gln Val  Tyr His Ser Gln Leu  Asn Met Ser His Gln  Phe Ser His 
    1160                 1165                 1170             


Phe Asn  Val Leu Thr His Gln  Thr Phe Leu Gly Thr  Pro Tyr Ala 
    1175                 1180                 1185             


Leu Ser  Ser Ser Gln Ser Gln  Glu Asn Glu Asn Tyr  Phe Leu Ser 
    1190                 1195                 1200             


Ala Tyr  Thr Glu Ser Leu Asp  Arg Asp Lys Ser Pro  Pro Pro Leu 
    1205                 1210                 1215             


Ser Trp  Gly Lys Ser Asp Ser  Ser Arg Pro Tyr Ser  Gln Glu Lys 
    1220                 1225                 1230             


<210>  3091
<211>  751
<212>  PRT
<213>  homo sapiens

<400>  3091

Met Gly Gln Thr Gly Lys Lys Ser Glu Lys Gly Pro Val Cys Trp Arg 
1               5                   10                  15      


Lys Arg Val Lys Ser Glu Tyr Met Arg Leu Arg Gln Leu Lys Arg Phe 
            20                  25                  30          


Arg Arg Ala Asp Glu Val Lys Ser Met Phe Ser Ser Asn Arg Gln Lys 
        35                  40                  45              


Ile Leu Glu Arg Thr Glu Ile Leu Asn Gln Glu Trp Lys Gln Arg Arg 
    50                  55                  60                  


Ile Gln Pro Val His Ile Leu Thr Ser Val Ser Ser Leu Arg Gly Thr 
65                  70                  75                  80  


Arg Glu Cys Ser Val Thr Ser Asp Leu Asp Phe Pro Thr Gln Val Ile 
                85                  90                  95      


Pro Leu Lys Thr Leu Asn Ala Val Ala Ser Val Pro Ile Met Tyr Ser 
            100                 105                 110         


Trp Ser Pro Leu Gln Gln Asn Phe Met Val Glu Asp Glu Thr Val Leu 
        115                 120                 125             


His Asn Ile Pro Tyr Met Gly Asp Glu Val Leu Asp Gln Asp Gly Thr 
    130                 135                 140                 


Phe Ile Glu Glu Leu Ile Lys Asn Tyr Asp Gly Lys Val His Gly Asp 
145                 150                 155                 160 


Arg Glu Cys Gly Phe Ile Asn Asp Glu Ile Phe Val Glu Leu Val Asn 
                165                 170                 175     


Ala Leu Gly Gln Tyr Asn Asp Asp Asp Asp Asp Asp Asp Gly Asp Asp 
            180                 185                 190         


Pro Glu Glu Arg Glu Glu Lys Gln Lys Asp Leu Glu Asp His Arg Asp 
        195                 200                 205             


Asp Lys Glu Ser Arg Pro Pro Arg Lys Phe Pro Ser Asp Lys Ile Phe 
    210                 215                 220                 


Glu Ala Ile Ser Ser Met Phe Pro Asp Lys Gly Thr Ala Glu Glu Leu 
225                 230                 235                 240 


Lys Glu Lys Tyr Lys Glu Leu Thr Glu Gln Gln Leu Pro Gly Ala Leu 
                245                 250                 255     


Pro Pro Glu Cys Thr Pro Asn Ile Asp Gly Pro Asn Ala Lys Ser Val 
            260                 265                 270         


Gln Arg Glu Gln Ser Leu His Ser Phe His Thr Leu Phe Cys Arg Arg 
        275                 280                 285             


Cys Phe Lys Tyr Asp Cys Phe Leu His Arg Lys Cys Asn Tyr Ser Phe 
    290                 295                 300                 


His Ala Thr Pro Asn Thr Tyr Lys Arg Lys Asn Thr Glu Thr Ala Leu 
305                 310                 315                 320 


Asp Asn Lys Pro Cys Gly Pro Gln Cys Tyr Gln His Leu Glu Gly Ala 
                325                 330                 335     


Lys Glu Phe Ala Ala Ala Leu Thr Ala Glu Arg Ile Lys Thr Pro Pro 
            340                 345                 350         


Lys Arg Pro Gly Gly Arg Arg Arg Gly Arg Leu Pro Asn Asn Ser Ser 
        355                 360                 365             


Arg Pro Ser Thr Pro Thr Ile Asn Val Leu Glu Ser Lys Asp Thr Asp 
    370                 375                 380                 


Ser Asp Arg Glu Ala Gly Thr Glu Thr Gly Gly Glu Asn Asn Asp Lys 
385                 390                 395                 400 


Glu Glu Glu Glu Lys Lys Asp Glu Thr Ser Ser Ser Ser Glu Ala Asn 
                405                 410                 415     


Ser Arg Cys Gln Thr Pro Ile Lys Met Lys Pro Asn Ile Glu Pro Pro 
            420                 425                 430         


Glu Asn Val Glu Trp Ser Gly Ala Glu Ala Ser Met Phe Arg Val Leu 
        435                 440                 445             


Ile Gly Thr Tyr Tyr Asp Asn Phe Cys Ala Ile Ala Arg Leu Ile Gly 
    450                 455                 460                 


Thr Lys Thr Cys Arg Gln Val Tyr Glu Phe Arg Val Lys Glu Ser Ser 
465                 470                 475                 480 


Ile Ile Ala Pro Ala Pro Ala Glu Asp Val Asp Thr Pro Pro Arg Lys 
                485                 490                 495     


Lys Lys Arg Lys His Arg Leu Trp Ala Ala His Cys Arg Lys Ile Gln 
            500                 505                 510         


Leu Lys Lys Asp Gly Ser Ser Asn His Val Tyr Asn Tyr Gln Pro Cys 
        515                 520                 525             


Asp His Pro Arg Gln Pro Cys Asp Ser Ser Cys Pro Cys Val Ile Ala 
    530                 535                 540                 


Gln Asn Phe Cys Glu Lys Phe Cys Gln Cys Ser Ser Glu Cys Gln Asn 
545                 550                 555                 560 


Arg Phe Pro Gly Cys Arg Cys Lys Ala Gln Cys Asn Thr Lys Gln Cys 
                565                 570                 575     


Pro Cys Tyr Leu Ala Val Arg Glu Cys Asp Pro Asp Leu Cys Leu Thr 
            580                 585                 590         


Cys Gly Ala Ala Asp His Trp Asp Ser Lys Asn Val Ser Cys Lys Asn 
        595                 600                 605             


Cys Ser Ile Gln Arg Gly Ser Lys Lys His Leu Leu Leu Ala Pro Ser 
    610                 615                 620                 


Asp Val Ala Gly Trp Gly Ile Phe Ile Lys Asp Pro Val Gln Lys Asn 
625                 630                 635                 640 


Glu Phe Ile Ser Glu Tyr Cys Gly Glu Ile Ile Ser Gln Asp Glu Ala 
                645                 650                 655     


Asp Arg Arg Gly Lys Val Tyr Asp Lys Tyr Met Cys Ser Phe Leu Phe 
            660                 665                 670         


Asn Leu Asn Asn Asp Phe Val Val Asp Ala Thr Arg Lys Gly Asn Lys 
        675                 680                 685             


Ile Arg Phe Ala Asn His Ser Val Asn Pro Asn Cys Tyr Ala Lys Val 
    690                 695                 700                 


Met Met Val Asn Gly Asp His Arg Ile Gly Ile Phe Ala Lys Arg Ala 
705                 710                 715                 720 


Ile Gln Thr Gly Glu Glu Leu Phe Phe Asp Tyr Arg Tyr Ser Gln Ala 
                725                 730                 735     


Asp Ala Leu Lys Tyr Val Gly Ile Glu Arg Glu Met Glu Ile Pro 
            740                 745                 750     


<210>  3092
<211>  325
<212>  PRT
<213>  homo sapiens

<400>  3092

Met Ala Arg Pro Val Ser Asp Arg Thr Pro Ala Pro Leu Leu Leu Gly 
1               5                   10                  15      


Gly Pro Ala Gly Thr Pro Pro Gly Gly Gly Ala Leu Leu Gly Leu Arg 
            20                  25                  30          


Ser Leu Leu Gln Gly Thr Ser Lys Pro Lys Glu Pro Ala Ser Cys Leu 
        35                  40                  45              


Leu Lys Glu Lys Glu Arg Lys Ala Ala Leu Pro Ala Ala Thr Thr Pro 
    50                  55                  60                  


Gly Pro Gly Leu Glu Thr Ala Gly Pro Ala Asp Ala Pro Ala Gly Ala 
65                  70                  75                  80  


Val Val Gly Gly Gly Ser Pro Arg Gly Arg Pro Gly Pro Val Pro Ala 
                85                  90                  95      


Pro Gly Leu Leu Ala Pro Leu Leu Trp Glu Arg Thr Leu Pro Phe Gly 
            100                 105                 110         


Asp Val Glu Tyr Val Asp Leu Asp Ala Phe Leu Leu Glu His Gly Leu 
        115                 120                 125             


Pro Pro Ser Pro Pro Pro Pro Gly Gly Pro Ser Pro Glu Pro Ser Pro 
    130                 135                 140                 


Ala Arg Thr Pro Ala Pro Ser Pro Gly Pro Gly Ser Cys Gly Ser Ala 
145                 150                 155                 160 


Ser Pro Arg Ser Ser Pro Gly His Ala Pro Ala Arg Ala Ala Leu Gly 
                165                 170                 175     


Thr Ala Ser Gly His Arg Ala Gly Leu Thr Ser Arg Asp Thr Pro Ser 
            180                 185                 190         


Pro Val Asp Pro Asp Thr Val Glu Val Leu Met Thr Phe Glu Pro Asp 
        195                 200                 205             


Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro Gly His Glu Thr Phe Asp 
    210                 215                 220                 


Pro Arg Arg His Arg Phe Ser Glu Glu Glu Leu Lys Pro Gln Pro Ile 
225                 230                 235                 240 


Met Lys Lys Ala Arg Lys Ile Gln Val Pro Glu Glu Gln Lys Asp Glu 
                245                 250                 255     


Lys Tyr Trp Ser Arg Arg Tyr Lys Asn Asn Glu Ala Ala Lys Arg Ser 
            260                 265                 270         


Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln Ile Ser Val Arg Ala Ala 
        275                 280                 285             


Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg Gln Glu Val Val Ala Val 
    290                 295                 300                 


Arg Gln Glu Leu Ser His Tyr Arg Ala Val Leu Ser Arg Tyr Gln Ala 
305                 310                 315                 320 


Gln His Gly Ala Leu 
                325 


<210>  3093
<211>  297
<212>  PRT
<213>  homo sapiens

<400>  3093

Met Met Ser Tyr Leu Lys Gln Pro Pro Tyr Ala Val Asn Gly Leu Ser 
1               5                   10                  15      


Leu Thr Thr Ser Gly Met Asp Leu Leu His Pro Ser Val Gly Tyr Pro 
            20                  25                  30          


Gly Pro Trp Ala Ser Cys Pro Ala Ala Thr Pro Arg Lys Gln Arg Arg 
        35                  40                  45              


Glu Arg Thr Thr Phe Thr Arg Ala Gln Leu Asp Val Leu Glu Ala Leu 
    50                  55                  60                  


Phe Ala Lys Thr Arg Tyr Pro Asp Ile Phe Met Arg Glu Glu Val Ala 
65                  70                  75                  80  


Leu Lys Ile Asn Leu Pro Glu Ser Arg Val Gln Val Trp Phe Lys Asn 
                85                  90                  95      


Arg Arg Ala Lys Cys Arg Gln Gln Gln Gln Gln Gln Gln Asn Gly Gly 
            100                 105                 110         


Gln Asn Lys Val Arg Pro Ala Lys Lys Lys Thr Ser Pro Ala Arg Glu 
        115                 120                 125             


Val Ser Ser Glu Ser Gly Thr Ser Gly Gln Phe Thr Pro Pro Ser Ser 
    130                 135                 140                 


Thr Ser Val Pro Thr Ile Ala Ser Ser Ser Ala Pro Val Ser Ile Trp 
145                 150                 155                 160 


Ser Pro Ala Ser Ile Ser Pro Leu Ser Asp Pro Leu Ser Thr Ser Ser 
                165                 170                 175     


Ser Cys Met Gln Arg Ser Tyr Pro Met Thr Tyr Thr Gln Ala Ser Gly 
            180                 185                 190         


Tyr Ser Gln Gly Tyr Ala Gly Ser Thr Ser Tyr Phe Gly Gly Met Asp 
        195                 200                 205             


Cys Gly Ser Tyr Leu Thr Pro Met His His Gln Leu Pro Gly Pro Gly 
    210                 215                 220                 


Ala Thr Leu Ser Pro Met Gly Thr Asn Ala Val Thr Ser His Leu Asn 
225                 230                 235                 240 


Gln Ser Pro Ala Ser Leu Ser Thr Gln Gly Tyr Gly Ala Ser Ser Leu 
                245                 250                 255     


Gly Phe Asn Ser Thr Thr Asp Cys Leu Asp Tyr Lys Asp Gln Thr Ala 
            260                 265                 270         


Ser Trp Lys Leu Asn Phe Asn Ala Asp Cys Leu Asp Tyr Lys Asp Gln 
        275                 280                 285             


Thr Ser Ser Trp Lys Phe Gln Val Leu 
    290                 295         


<210>  3094
<211>  437
<212>  PRT
<213>  homo sapiens

<400>  3094

Met Phe Val Leu Phe Leu Cys Asn Leu Ser Leu Val Pro Ala Ala Ala 
1               5                   10                  15      


Ser Lys Asn Lys Val Lys Gly Ser Gln Gly Gln Phe Pro Leu Thr Gln 
            20                  25                  30          


Asn Val Thr Val Val Glu Gly Gly Thr Ala Ile Leu Thr Cys Arg Val 
        35                  40                  45              


Asp Gln Asn Asp Asn Thr Ser Leu Gln Trp Ser Asn Pro Ala Gln Gln 
    50                  55                  60                  


Thr Leu Tyr Phe Asp Asp Lys Lys Ala Leu Arg Asp Asn Arg Ile Glu 
65                  70                  75                  80  


Leu Val Arg Ala Ser Trp His Glu Leu Ser Ile Ser Val Ser Asp Val 
                85                  90                  95      


Ser Leu Ser Asp Glu Gly Gln Tyr Thr Cys Ser Leu Phe Thr Met Pro 
            100                 105                 110         


Val Lys Thr Ser Lys Ala Tyr Leu Thr Val Leu Gly Val Pro Glu Lys 
        115                 120                 125             


Pro Gln Ile Ser Gly Phe Ser Ser Pro Val Met Glu Gly Asp Leu Met 
    130                 135                 140                 


Gln Leu Thr Cys Lys Thr Ser Gly Ser Lys Pro Ala Ala Asp Ile Arg 
145                 150                 155                 160 


Trp Phe Lys Asn Asp Lys Glu Ile Lys Asp Val Lys Tyr Leu Lys Glu 
                165                 170                 175     


Glu Asp Ala Asn Arg Lys Thr Phe Thr Val Ser Ser Thr Leu Asp Phe 
            180                 185                 190         


Arg Val Asp Arg Ser Asp Asp Gly Val Ala Val Ile Cys Arg Val Asp 
        195                 200                 205             


His Glu Ser Leu Asn Ala Thr Pro Gln Val Ala Met Gln Val Leu Glu 
    210                 215                 220                 


Ile His Tyr Thr Pro Ser Val Lys Ile Ile Pro Ser Thr Pro Phe Pro 
225                 230                 235                 240 


Gln Glu Gly Gln Pro Leu Ile Leu Thr Cys Glu Ser Lys Gly Lys Pro 
                245                 250                 255     


Leu Pro Glu Pro Val Leu Trp Thr Lys Asp Gly Gly Glu Leu Pro Asp 
            260                 265                 270         


Pro Asp Arg Met Val Val Ser Gly Arg Glu Leu Asn Ile Leu Phe Leu 
        275                 280                 285             


Asn Lys Thr Asp Asn Gly Thr Tyr Arg Cys Glu Ala Thr Asn Thr Ile 
    290                 295                 300                 


Gly Gln Ser Ser Ala Glu Tyr Val Leu Ile Val His Asp Val Pro Asn 
305                 310                 315                 320 


Thr Leu Leu Pro Thr Thr Ile Ile Pro Ser Leu Thr Thr Ala Thr Val 
                325                 330                 335     


Thr Thr Thr Val Ala Ile Thr Thr Ser Pro Thr Thr Ser Ala Thr Thr 
            340                 345                 350         


Ser Ser Ile Arg Asp Pro Asn Ala Leu Ala Gly Gln Asn Gly Pro Asp 
        355                 360                 365             


His Ala Leu Ile Gly Gly Ile Val Ala Val Val Val Phe Val Thr Leu 
    370                 375                 380                 


Cys Ser Ile Phe Leu Leu Gly Arg Tyr Leu Ala Arg His Lys Gly Thr 
385                 390                 395                 400 


Tyr Leu Thr Asn Glu Ala Lys Gly Ala Glu Asp Ala Pro Asp Ala Asp 
                405                 410                 415     


Thr Ala Ile Ile Asn Ala Glu Gly Ser Gln Val Asn Ala Glu Glu Lys 
            420                 425                 430         


Lys Glu Tyr Phe Ile 
        435         


<210>  3095
<211>  431
<212>  PRT
<213>  homo sapiens

<400>  3095

Met Ser Asp Gln Ile Lys Phe Ile Met Asp Ser Leu Asn Lys Glu Pro 
1               5                   10                  15      


Phe Arg Lys Asn Tyr Asn Leu Ile Thr Phe Asp Ser Leu Glu Pro Met 
            20                  25                  30          


Gln Leu Leu Gln Val Leu Ser Asp Val Leu Ala Glu Ile Asp Pro Lys 
        35                  40                  45              


Gln Leu Val Asp Ile Arg Glu Glu Met Pro Glu Gln Thr Ala Lys Arg 
    50                  55                  60                  


Met Leu Ser Leu Leu Gly Ile Leu Lys Tyr Lys Pro Ser Gly Asn Ala 
65                  70                  75                  80  


Thr Asp Met Ser Thr Phe Arg Gln Gly Leu Val Ile Gly Ser Lys Pro 
                85                  90                  95      


Val Ile Tyr Pro Val Leu His Trp Leu Leu Gln Arg Thr Asn Glu Leu 
            100                 105                 110         


Lys Lys Arg Ala Tyr Leu Ala Arg Phe Leu Ile Lys Leu Glu Val Pro 
        115                 120                 125             


Ser Glu Phe Leu Gln Asp Glu Thr Val Ala Asp Thr Asn Lys Gln Tyr 
    130                 135                 140                 


Glu Glu Leu Met Glu Ala Phe Lys Thr Leu His Lys Glu Tyr Glu Gln 
145                 150                 155                 160 


Leu Lys Ile Ser Gly Phe Ser Thr Ala Glu Ile Arg Lys Asp Ile Ser 
                165                 170                 175     


Ala Met Glu Glu Glu Lys Asp Gln Leu Ile Lys Arg Val Glu His Leu 
            180                 185                 190         


Lys Lys Arg Val Glu Thr Ala Gln Asn His Gln Trp Met Leu Lys Ile 
        195                 200                 205             


Ala Arg Gln Leu Arg Val Glu Lys Glu Arg Glu Glu Tyr Leu Ala Gln 
    210                 215                 220                 


Gln Lys Gln Glu Gln Lys Asn Gln Leu Phe His Ala Val Gln Arg Leu 
225                 230                 235                 240 


Gln Arg Val Gln Asn Gln Leu Lys Ser Met Arg Gln Ala Ala Ala Asp 
                245                 250                 255     


Ala Lys Pro Glu Ser Leu Met Lys Arg Leu Glu Glu Glu Ile Lys Phe 
            260                 265                 270         


Asn Leu Tyr Met Val Thr Glu Lys Phe Pro Lys Glu Leu Glu Asn Lys 
        275                 280                 285             


Lys Lys Glu Leu His Phe Leu Gln Lys Val Val Ser Glu Pro Ala Met 
    290                 295                 300                 


Gly His Ser Asp Leu Leu Glu Leu Glu Ser Lys Ile Asn Glu Ile Asn 
305                 310                 315                 320 


Thr Glu Ile Asn Gln Leu Ile Glu Lys Lys Met Met Arg Asn Glu Pro 
                325                 330                 335     


Ile Glu Gly Lys Leu Ser Leu Tyr Arg Gln Gln Ala Ser Ile Ile Ser 
            340                 345                 350         


Arg Lys Lys Glu Ala Lys Ala Glu Glu Leu Gln Glu Ala Lys Glu Lys 
        355                 360                 365             


Leu Ala Ser Leu Glu Arg Glu Ala Ser Val Lys Arg Asn Gln Thr Arg 
    370                 375                 380                 


Glu Phe Asp Gly Thr Glu Val Leu Lys Gly Asp Glu Arg Gln Asp Leu 
385                 390                 395                 400 


Thr Leu Ser Pro Arg Leu Glu Cys Gly Gly Val Ile Met Ala Tyr Cys 
                405                 410                 415     


Ser Leu Lys Leu Leu Gly Ser Ser Asp Pro Pro Thr Ser Ala Ser 
            420                 425                 430     


<210>  3096
<211>  420
<212>  PRT
<213>  homo sapiens

<400>  3096

Met Pro Gly Gly Cys Ser Arg Gly Pro Ala Ala Gly Asp Gly Arg Leu 
1               5                   10                  15      


Arg Leu Ala Arg Leu Ala Leu Val Leu Leu Gly Trp Val Ser Ser Ser 
            20                  25                  30          


Ser Pro Thr Ser Ser Ala Ser Ser Phe Ser Ser Ser Ala Pro Phe Leu 
        35                  40                  45              


Ala Ser Ala Val Ser Ala Gln Pro Pro Leu Pro Asp Gln Cys Pro Ala 
    50                  55                  60                  


Leu Cys Glu Cys Ser Glu Ala Ala Arg Thr Val Lys Cys Val Asn Arg 
65                  70                  75                  80  


Asn Leu Thr Glu Val Pro Thr Asp Leu Pro Ala Tyr Val Arg Asn Leu 
                85                  90                  95      


Phe Leu Thr Gly Asn Gln Leu Ala Val Leu Pro Ala Gly Ala Phe Ala 
            100                 105                 110         


Arg Arg Pro Pro Leu Ala Glu Leu Ala Ala Leu Asn Leu Ser Gly Ser 
        115                 120                 125             


Arg Leu Asp Glu Val Arg Ala Gly Ala Phe Glu His Leu Pro Ser Leu 
    130                 135                 140                 


Arg Gln Leu Asp Leu Ser His Asn Pro Leu Ala Asp Leu Ser Pro Phe 
145                 150                 155                 160 


Ala Phe Ser Gly Ser Asn Ala Ser Val Ser Ala Pro Ser Pro Leu Val 
                165                 170                 175     


Glu Leu Ile Leu Asn His Ile Val Pro Pro Glu Asp Glu Arg Gln Asn 
            180                 185                 190         


Arg Ser Phe Glu Gly Met Val Val Ala Ala Leu Leu Ala Gly Arg Ala 
        195                 200                 205             


Leu Gln Gly Leu Arg Arg Leu Glu Leu Ala Ser Asn His Phe Leu Tyr 
    210                 215                 220                 


Leu Pro Arg Asp Val Leu Ala Gln Leu Pro Ser Leu Arg His Leu Asp 
225                 230                 235                 240 


Leu Ser Asn Asn Ser Leu Val Ser Leu Thr Tyr Val Ser Phe Arg Asn 
                245                 250                 255     


Leu Thr His Leu Glu Ser Leu His Leu Glu Asp Asn Ala Leu Lys Val 
            260                 265                 270         


Leu His Asn Gly Thr Leu Ala Glu Leu Gln Gly Leu Pro His Ile Arg 
        275                 280                 285             


Val Phe Leu Asp Asn Asn Pro Trp Val Cys Asp Cys His Met Ala Asp 
    290                 295                 300                 


Met Val Thr Trp Leu Lys Glu Thr Glu Val Val Gln Gly Lys Asp Arg 
305                 310                 315                 320 


Leu Thr Cys Ala Tyr Pro Glu Lys Met Arg Asn Arg Val Leu Leu Glu 
                325                 330                 335     


Leu Asn Ser Ala Asp Leu Asp Cys Asp Pro Ile Leu Pro Pro Ser Leu 
            340                 345                 350         


Gln Thr Ser Tyr Val Phe Leu Gly Ile Val Leu Ala Leu Ile Gly Ala 
        355                 360                 365             


Ile Phe Leu Leu Val Leu Tyr Leu Asn Arg Lys Gly Ile Lys Lys Trp 
    370                 375                 380                 


Met His Asn Ile Arg Asp Ala Cys Arg Asp His Met Glu Gly Tyr His 
385                 390                 395                 400 


Tyr Arg Tyr Glu Ile Asn Ala Asp Pro Arg Leu Thr Asn Leu Ser Ser 
                405                 410                 415     


Asn Ser Asp Val 
            420 


<210>  3097
<211>  420
<212>  PRT
<213>  homo sapiens

<400>  3097

Met Pro Gly Gly Cys Ser Arg Gly Pro Ala Ala Gly Asp Gly Arg Leu 
1               5                   10                  15      


Arg Leu Ala Arg Leu Ala Leu Val Leu Leu Gly Trp Val Ser Ser Ser 
            20                  25                  30          


Ser Pro Thr Ser Ser Ala Ser Ser Phe Ser Ser Ser Ala Pro Phe Leu 
        35                  40                  45              


Ala Ser Ala Val Ser Ala Gln Pro Pro Leu Pro Asp Gln Cys Pro Ala 
    50                  55                  60                  


Leu Cys Glu Cys Ser Glu Ala Ala Arg Thr Val Lys Cys Val Asn Arg 
65                  70                  75                  80  


Asn Leu Thr Glu Val Pro Thr Asp Leu Pro Ala Tyr Val Arg Asn Leu 
                85                  90                  95      


Phe Leu Thr Gly Asn Gln Leu Ala Val Leu Pro Ala Gly Ala Phe Ala 
            100                 105                 110         


Arg Arg Pro Pro Leu Ala Glu Leu Ala Ala Leu Asn Leu Ser Gly Ser 
        115                 120                 125             


Arg Leu Asp Glu Val Arg Ala Gly Ala Phe Glu His Leu Pro Ser Leu 
    130                 135                 140                 


Arg Gln Leu Asp Leu Ser His Asn Pro Leu Ala Asp Leu Ser Pro Phe 
145                 150                 155                 160 


Ala Phe Ser Gly Ser Asn Ala Ser Val Ser Ala Pro Ser Pro Leu Val 
                165                 170                 175     


Glu Leu Ile Leu Asn His Ile Val Pro Pro Glu Asp Glu Arg Gln Asn 
            180                 185                 190         


Arg Ser Phe Glu Gly Met Val Val Ala Ala Leu Leu Ala Gly Arg Ala 
        195                 200                 205             


Leu Gln Gly Leu Arg Arg Leu Glu Leu Ala Ser Asn His Phe Leu Tyr 
    210                 215                 220                 


Leu Pro Arg Asp Val Leu Ala Gln Leu Pro Ser Leu Arg His Leu Asp 
225                 230                 235                 240 


Leu Ser Asn Asn Ser Leu Val Ser Leu Thr Tyr Val Ser Phe Arg Asn 
                245                 250                 255     


Leu Thr His Leu Glu Ser Leu His Leu Glu Asp Asn Ala Leu Lys Val 
            260                 265                 270         


Leu His Asn Gly Thr Leu Ala Glu Leu Gln Gly Leu Pro His Ile Arg 
        275                 280                 285             


Val Phe Leu Asp Asn Asn Pro Trp Val Cys Asp Cys His Met Ala Asp 
    290                 295                 300                 


Met Val Thr Trp Leu Lys Glu Thr Glu Val Val Gln Gly Lys Asp Arg 
305                 310                 315                 320 


Leu Thr Cys Ala Tyr Pro Glu Lys Met Arg Asn Arg Val Leu Leu Glu 
                325                 330                 335     


Leu Asn Ser Ala Asp Leu Asp Cys Asp Pro Ile Leu Pro Pro Ser Leu 
            340                 345                 350         


Gln Thr Ser Tyr Val Phe Leu Gly Ile Val Leu Ala Leu Ile Gly Ala 
        355                 360                 365             


Ile Phe Leu Leu Val Leu Tyr Leu Asn Arg Lys Gly Ile Lys Lys Trp 
    370                 375                 380                 


Met His Asn Ile Arg Asp Ala Cys Arg Asp His Met Glu Gly Tyr His 
385                 390                 395                 400 


Tyr Arg Tyr Glu Ile Asn Ala Asp Pro Arg Leu Thr Asn Leu Ser Ser 
                405                 410                 415     


Asn Ser Asp Val 
            420 


<210>  3098
<211>  204
<212>  PRT
<213>  homo sapiens

<400>  3098

Met Glu Ala Gln Ala Gln Gly Leu Leu Glu Thr Glu Pro Leu Gln Gly 
1               5                   10                  15      


Thr Asp Glu Asp Ala Val Ala Ser Ala Asp Phe Ser Ser Met Leu Ser 
            20                  25                  30          


Glu Glu Glu Lys Glu Glu Leu Lys Ala Glu Leu Val Gln Leu Glu Asp 
        35                  40                  45              


Glu Ile Thr Thr Leu Arg Gln Val Leu Ser Ala Lys Glu Arg His Leu 
    50                  55                  60                  


Val Glu Ile Lys Gln Lys Leu Gly Met Asn Leu Met Asn Glu Leu Lys 
65                  70                  75                  80  


Gln Asn Phe Ser Lys Ser Trp His Asp Met Gln Thr Thr Thr Ala Tyr 
                85                  90                  95      


Lys Lys Thr His Glu Thr Leu Ser His Ala Gly Gln Lys Ala Thr Ala 
            100                 105                 110         


Ala Phe Ser Asn Val Gly Thr Ala Ile Ser Lys Lys Phe Gly Asp Met 
        115                 120                 125             


Ser Tyr Ser Ile Arg His Ser Ile Ser Met Pro Ala Met Arg Asn Ser 
    130                 135                 140                 


Pro Thr Phe Lys Ser Phe Glu Glu Arg Val Glu Thr Thr Val Thr Ser 
145                 150                 155                 160 


Leu Lys Thr Lys Val Gly Gly Thr Asn Pro Asn Gly Gly Ser Phe Glu 
                165                 170                 175     


Glu Val Leu Ser Ser Thr Ala His Ala Ser Ala Gln Ser Leu Ala Gly 
            180                 185                 190         


Gly Ser Arg Arg Thr Lys Glu Glu Glu Leu Gln Cys 
        195                 200                 


<210>  3099
<211>  175
<212>  PRT
<213>  homo sapiens

<400>  3099

Met Leu Ser Glu Glu Glu Lys Glu Glu Leu Lys Ala Glu Leu Val Gln 
1               5                   10                  15      


Leu Glu Asp Glu Ile Thr Thr Leu Arg Gln Val Leu Ser Ala Lys Glu 
            20                  25                  30          


Arg His Leu Val Glu Ile Lys Gln Lys Leu Gly Met Asn Leu Met Asn 
        35                  40                  45              


Glu Leu Lys Gln Asn Phe Ser Lys Ser Trp His Asp Met Gln Thr Thr 
    50                  55                  60                  


Thr Ala Tyr Lys Lys Thr His Glu Thr Leu Ser His Ala Gly Gln Lys 
65                  70                  75                  80  


Ala Thr Ala Ala Phe Ser Asn Val Gly Thr Ala Ile Ser Lys Lys Phe 
                85                  90                  95      


Gly Asp Met Ser Tyr Ser Ile Arg His Ser Ile Ser Met Pro Ala Met 
            100                 105                 110         


Arg Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Arg Val Glu Thr Thr 
        115                 120                 125             


Val Thr Ser Leu Lys Thr Lys Val Gly Gly Thr Asn Pro Asn Gly Gly 
    130                 135                 140                 


Ser Phe Glu Glu Val Leu Ser Ser Thr Ala His Ala Ser Ala Gln Ser 
145                 150                 155                 160 


Leu Ala Gly Gly Ser Arg Arg Thr Lys Glu Glu Glu Leu Gln Cys 
                165                 170                 175 


<210>  3100
<211>  144
<212>  PRT
<213>  homo sapiens

<400>  3100

Met Glu Ala Gln Ala Gln Gly Leu Leu Glu Thr Glu Pro Leu Gln Gly 
1               5                   10                  15      


Thr Asp Glu Asp Ala Val Ala Ser Ala Asp Phe Ser Ser Met Leu Ser 
            20                  25                  30          


Glu Glu Glu Lys Glu Glu Leu Lys Ala Glu Leu Val Gln Leu Glu Asp 
        35                  40                  45              


Glu Ile Thr Thr Leu Arg Gln Val Leu Ser Ala Lys Glu Arg His Leu 
    50                  55                  60                  


Val Glu Ile Lys Gln Lys Leu Gly Met Asn Leu Met Asn Glu Leu Lys 
65                  70                  75                  80  


Gln Asn Phe Ser Lys Ser Trp His Asp Met Gln Thr Thr Thr Ala Tyr 
                85                  90                  95      


Lys Lys Thr His Glu Thr Leu Ser His Ala Gly Gln Lys Ala Thr Ala 
            100                 105                 110         


Ala Phe Ser Asn Val Gly Thr Ala Ile Ser Lys Lys Phe Gly Asp Met 
        115                 120                 125             


Ser Tyr Ser Ile Arg His Ser Ile Ser Met Pro Ala Met Arg Arg Lys 
    130                 135                 140                 


<210>  3101
<211>  131
<212>  PRT
<213>  homo sapiens

<400>  3101

Met Glu Ala Gln Ala Gln Gly Leu Leu Glu Thr Glu Pro Leu Gln Gly 
1               5                   10                  15      


Thr Asp Glu Asp Ala Val Ala Ser Ala Asp Phe Ser Ser Met Leu Ser 
            20                  25                  30          


Glu Glu Glu Lys Glu Glu Leu Lys Ala Glu Leu Val Gln Leu Glu Asp 
        35                  40                  45              


Glu Ile Thr Thr Leu Arg Gln Val Leu Ser Ala Lys Glu Arg His Leu 
    50                  55                  60                  


Val Glu Ile Lys Gln Lys Leu Gly Met Asn Leu Met Asn Glu Leu Lys 
65                  70                  75                  80  


Gln Asn Phe Ser Lys Ser Trp His Asp Met Gln Thr Thr Thr Ala Tyr 
                85                  90                  95      


Lys Lys Thr His Glu Thr Leu Ser His Ala Gly Gln Lys Ala Thr Ala 
            100                 105                 110         


Ala Phe Ser Asn Val Gly Thr Ala Ile Ser Lys Lys Phe Gly Asp Met 
        115                 120                 125             


Arg Arg Lys 
    130     


<210>  3102
<211>  641
<212>  PRT
<213>  homo sapiens

<400>  3102

Met Asn Trp Ala Ala Phe Gly Gly Ser Glu Phe Phe Ile Pro Glu Gly 
1               5                   10                  15      


Ile Gln Ile Asp Ser Arg Cys Pro Leu Ser Arg Asn Ile Thr Glu Trp 
            20                  25                  30          


Tyr His Tyr Tyr Gly Ile Ala Val Lys Glu Ser Ser Gln Tyr Tyr Asp 
        35                  40                  45              


Val Met Tyr Ser Lys Lys Gly Ala Ala Trp Val Ser Glu Thr Gly Lys 
    50                  55                  60                  


Lys Glu Val Ser Lys Gln Thr Val Ala Tyr Ser Pro Arg Ser Lys Leu 
65                  70                  75                  80  


Gly Thr Leu Leu Pro Glu Phe Pro Asn Val Lys Asp Leu Asn Leu Pro 
                85                  90                  95      


Ala Ser Leu Pro Glu Glu Lys Val Ser Thr Phe Ile Met Met Tyr Arg 
            100                 105                 110         


Thr His Cys Gln Arg Ile Leu Asp Thr Val Ile Arg Ala Asn Phe Asp 
        115                 120                 125             


Glu Val Gln Ser Phe Leu Leu His Phe Trp Gln Gly Met Pro Pro His 
    130                 135                 140                 


Met Leu Pro Val Leu Gly Ser Ser Thr Val Val Asn Ile Val Gly Val 
145                 150                 155                 160 


Cys Asp Ser Ile Leu Tyr Lys Ala Ile Ser Gly Val Leu Met Pro Thr 
                165                 170                 175     


Val Leu Gln Ala Leu Pro Asp Ser Leu Thr Gln Val Ile Arg Lys Phe 
            180                 185                 190         


Ala Lys Gln Leu Asp Glu Trp Leu Lys Val Ala Leu His Asp Leu Pro 
        195                 200                 205             


Glu Asn Leu Arg Asn Ile Lys Phe Glu Leu Ser Arg Arg Phe Ser Gln 
    210                 215                 220                 


Ile Leu Arg Arg Gln Thr Ser Leu Asn His Leu Cys Gln Ala Ser Arg 
225                 230                 235                 240 


Thr Val Ile His Ser Ala Asp Ile Thr Phe Gln Met Leu Glu Asp Trp 
                245                 250                 255     


Arg Asn Val Asp Leu Asn Ser Ile Thr Lys Gln Thr Leu Tyr Thr Met 
            260                 265                 270         


Glu Asp Ser Arg Asp Glu His Arg Lys Leu Ile Thr Gln Leu Tyr Gln 
        275                 280                 285             


Glu Phe Asp His Leu Leu Glu Glu Gln Ser Pro Ile Glu Ser Tyr Ile 
    290                 295                 300                 


Glu Trp Leu Asp Thr Met Val Asp Arg Cys Val Val Lys Val Ala Ala 
305                 310                 315                 320 


Lys Arg Gln Gly Ser Leu Lys Lys Val Ala Gln Gln Phe Leu Leu Met 
                325                 330                 335     


Trp Ser Cys Phe Gly Thr Arg Val Ile Arg Asp Met Thr Leu His Ser 
            340                 345                 350         


Ala Pro Ser Phe Gly Ser Phe His Leu Ile His Leu Met Phe Asp Asp 
        355                 360                 365             


Tyr Val Leu Tyr Leu Leu Glu Ser Leu His Cys Gln Glu Arg Ala Asn 
    370                 375                 380                 


Glu Leu Met Arg Ala Met Lys Gly Glu Gly Ser Thr Ala Glu Val Arg 
385                 390                 395                 400 


Glu Glu Ile Ile Leu Thr Glu Ala Ala Ala Pro Thr Pro Ser Pro Val 
                405                 410                 415     


Pro Ser Phe Ser Pro Ala Lys Ser Ala Thr Ser Val Glu Val Pro Pro 
            420                 425                 430         


Pro Ser Ser Pro Val Ser Asn Pro Ser Pro Glu Tyr Thr Gly Leu Ser 
        435                 440                 445             


Thr Thr Gly Ala Met Gln Ser Tyr Thr Trp Ser Leu Thr Tyr Thr Val 
    450                 455                 460                 


Thr Thr Ala Ala Gly Ser Pro Ala Glu Asn Ser Gln Gln Leu Pro Cys 
465                 470                 475                 480 


Met Arg Asn Thr His Val Pro Ser Ser Ser Val Thr His Arg Ile Pro 
                485                 490                 495     


Val Tyr Pro His Arg Glu Glu His Gly Tyr Thr Gly Ser Tyr Asn Tyr 
            500                 505                 510         


Gly Ser Tyr Gly Asn Gln His Pro His Pro Met Gln Ser Gln Tyr Pro 
        515                 520                 525             


Ala Leu Pro His Asp Thr Ala Ile Ser Gly Pro Leu His Tyr Ala Pro 
    530                 535                 540                 


Tyr His Arg Ser Ser Ala Gln Tyr Pro Phe Asn Ser Pro Thr Ser Arg 
545                 550                 555                 560 


Met Glu Pro Cys Leu Met Ser Ser Thr Pro Arg Leu His Pro Thr Pro 
                565                 570                 575     


Val Thr Pro Arg Trp Pro Glu Val Pro Ser Ala Asn Thr Cys Tyr Thr 
            580                 585                 590         


Ser Pro Ser Val His Ser Ala Arg Tyr Gly Asn Ser Ser Asp Met Tyr 
        595                 600                 605             


Thr Pro Leu Thr Thr Arg Arg Asn Ser Glu Tyr Glu His Met Gln His 
    610                 615                 620                 


Phe Pro Gly Phe Ala Tyr Ile Asn Gly Glu Ala Ser Thr Gly Trp Ala 
625                 630                 635                 640 


Lys 
    


<210>  3103
<211>  669
<212>  PRT
<213>  homo sapiens

<400>  3103

Met Met Arg Leu Arg Gly Ser Gly Met Leu Arg Asp Leu Leu Leu Arg 
1               5                   10                  15      


Ser Pro Ala Gly Val Ser Ala Thr Leu Arg Arg Ala Gln Pro Leu Val 
            20                  25                  30          


Thr Leu Cys Arg Arg Pro Arg Gly Gly Gly Arg Pro Ala Ala Gly Pro 
        35                  40                  45              


Ala Ala Ala Ala Arg Leu His Pro Trp Trp Gly Gly Gly Gly Trp Pro 
    50                  55                  60                  


Ala Glu Pro Leu Ala Arg Gly Leu Ser Ser Ser Pro Ser Glu Ile Leu 
65                  70                  75                  80  


Gln Glu Leu Gly Lys Gly Ser Thr His Pro Gln Pro Gly Val Ser Pro 
                85                  90                  95      


Pro Ala Ala Pro Ala Ala Pro Gly Pro Lys Asp Gly Pro Gly Glu Thr 
            100                 105                 110         


Asp Ala Phe Gly Asn Ser Glu Gly Lys Glu Leu Val Ala Ser Gly Glu 
        115                 120                 125             


Asn Lys Ile Lys Gln Gly Leu Leu Pro Ser Leu Glu Asp Leu Leu Phe 
    130                 135                 140                 


Tyr Thr Ile Ala Glu Gly Gln Glu Lys Ile Pro Val His Lys Phe Ile 
145                 150                 155                 160 


Thr Ala Leu Lys Ser Thr Gly Leu Arg Thr Ser Asp Pro Arg Leu Lys 
                165                 170                 175     


Glu Cys Met Asp Met Leu Arg Leu Thr Leu Gln Thr Thr Ser Asp Gly 
            180                 185                 190         


Val Met Leu Asp Lys Asp Leu Phe Lys Lys Cys Val Gln Ser Asn Ile 
        195                 200                 205             


Val Leu Leu Thr Gln Ala Phe Arg Arg Lys Phe Val Ile Pro Asp Phe 
    210                 215                 220                 


Met Ser Phe Thr Ser His Ile Asp Glu Leu Tyr Glu Ser Ala Lys Lys 
225                 230                 235                 240 


Gln Ser Gly Gly Lys Val Ala Asp Tyr Ile Pro Gln Leu Ala Lys Phe 
                245                 250                 255     


Ser Pro Asp Leu Trp Gly Val Ser Val Cys Thr Val Asp Gly Gln Arg 
            260                 265                 270         


His Ser Thr Gly Asp Thr Lys Val Pro Phe Cys Leu Gln Ser Cys Val 
        275                 280                 285             


Lys Pro Leu Lys Tyr Ala Ile Ala Val Asn Asp Leu Gly Thr Glu Tyr 
    290                 295                 300                 


Val His Arg Tyr Val Gly Lys Glu Pro Ser Gly Leu Arg Phe Asn Lys 
305                 310                 315                 320 


Leu Phe Leu Asn Glu Asp Asp Lys Pro His Asn Pro Met Val Asn Ala 
                325                 330                 335     


Gly Ala Ile Val Val Thr Ser Leu Ile Lys Gln Gly Val Asn Asn Ala 
            340                 345                 350         


Glu Lys Phe Asp Tyr Val Met Gln Phe Leu Asn Lys Met Ala Gly Asn 
        355                 360                 365             


Glu Tyr Val Gly Phe Ser Asn Ala Thr Phe Gln Ser Glu Arg Glu Ser 
    370                 375                 380                 


Gly Asp Arg Asn Phe Ala Ile Gly Tyr Tyr Leu Lys Glu Lys Lys Cys 
385                 390                 395                 400 


Phe Pro Glu Gly Thr Asp Met Val Gly Ile Leu Asp Phe Tyr Phe Gln 
                405                 410                 415     


Leu Cys Ser Ile Glu Val Thr Cys Glu Ser Ala Ser Val Met Ala Ala 
            420                 425                 430         


Thr Leu Ala Asn Gly Gly Phe Cys Pro Ile Thr Gly Glu Arg Val Leu 
        435                 440                 445             


Ser Pro Glu Ala Val Arg Asn Thr Leu Ser Leu Met His Ser Cys Gly 
    450                 455                 460                 


Met Tyr Asp Phe Ser Gly Gln Phe Ala Phe His Val Gly Leu Pro Ala 
465                 470                 475                 480 


Lys Ser Gly Val Ala Gly Gly Ile Leu Leu Val Val Pro Asn Val Met 
                485                 490                 495     


Gly Met Met Cys Trp Ser Pro Pro Leu Asp Lys Met Gly Asn Ser Val 
            500                 505                 510         


Lys Gly Ile His Phe Cys His Asp Leu Val Ser Leu Cys Asn Phe His 
        515                 520                 525             


Asn Tyr Asp Asn Leu Arg His Phe Ala Lys Lys Leu Asp Pro Arg Arg 
    530                 535                 540                 


Glu Gly Gly Asp Gln Arg Val Lys Ser Val Ile Asn Leu Leu Phe Ala 
545                 550                 555                 560 


Ala Tyr Thr Gly Asp Val Ser Ala Leu Arg Arg Phe Ala Leu Ser Ala 
                565                 570                 575     


Met Asp Met Glu Gln Arg Asp Tyr Asp Ser Arg Thr Ala Leu His Val 
            580                 585                 590         


Ala Ala Ala Glu Gly His Val Glu Val Val Lys Phe Leu Leu Glu Ala 
        595                 600                 605             


Cys Lys Val Asn Pro Phe Pro Lys Asp Arg Trp Asn Asn Thr Pro Met 
    610                 615                 620                 


Asp Glu Ala Leu His Phe Gly His His Asp Val Phe Lys Ile Leu Gln 
625                 630                 635                 640 


Glu Tyr Gln Val Gln Tyr Thr Pro Gln Gly Asp Ser Asp Asn Gly Lys 
                645                 650                 655     


Glu Asn Gln Thr Val His Lys Asn Leu Asp Gly Leu Leu 
            660                 665                 


<210>  3104
<211>  245
<212>  PRT
<213>  homo sapiens

<400>  3104

Met Thr Ser Ser Tyr Gly His Val Leu Glu Arg Gln Pro Ala Leu Gly 
1               5                   10                  15      


Gly Arg Leu Asp Ser Pro Gly Asn Leu Asp Thr Leu Gln Ala Lys Lys 
            20                  25                  30          


Asn Phe Ser Val Ser His Leu Leu Asp Leu Glu Glu Ala Gly Asp Met 
        35                  40                  45              


Val Ala Ala Gln Ala Asp Glu Asn Val Gly Glu Ala Gly Arg Ser Leu 
    50                  55                  60                  


Leu Glu Ser Pro Gly Leu Thr Ser Gly Ser Asp Thr Pro Gln Gln Asp 
65                  70                  75                  80  


Asn Asp Gln Leu Asn Ser Glu Glu Lys Lys Lys Arg Lys Gln Arg Arg 
                85                  90                  95      


Asn Arg Thr Thr Phe Asn Ser Ser Gln Leu Gln Ala Leu Glu Arg Val 
            100                 105                 110         


Phe Glu Arg Thr His Tyr Pro Asp Ala Phe Val Arg Glu Asp Leu Ala 
        115                 120                 125             


Arg Arg Val Asn Leu Thr Glu Ala Arg Val Gln Val Trp Phe Gln Asn 
    130                 135                 140                 


Arg Arg Ala Lys Phe Arg Arg Asn Glu Arg Ala Met Leu Ala Asn Lys 
145                 150                 155                 160 


Asn Ala Ser Leu Leu Lys Ser Tyr Ser Gly Asp Val Thr Ala Val Glu 
                165                 170                 175     


Gln Pro Ile Val Pro Arg Pro Ala Pro Arg Pro Thr Asp Tyr Leu Ser 
            180                 185                 190         


Trp Gly Thr Ala Ser Pro Tyr Ser Ala Met Ala Thr Tyr Ser Ala Thr 
        195                 200                 205             


Cys Ala Asn Asn Ser Pro Ala Gln Gly Ile Asn Met Ala Asn Ser Ile 
    210                 215                 220                 


Ala Asn Leu Arg Leu Lys Ala Lys Glu Tyr Ser Leu Gln Arg Asn Gln 
225                 230                 235                 240 


Val Pro Thr Val Asn 
                245 


<210>  3105
<211>  1512
<212>  PRT
<213>  homo sapiens

<400>  3105

Met Ala Thr Ala Val Glu Thr Glu Ala Cys Gln Pro Thr Asp Ala Ser 
1               5                   10                  15      


Trp Glu Ser Gly Gly Gly Gly Asp Asp Glu Met Lys Gln Ala Leu Pro 
            20                  25                  30          


Glu Leu Glu Ser Ser Gln Gln Asn Gly Gly Gly Gly Gly Leu Asn Ile 
        35                  40                  45              


Ala Glu Pro Ser Gly Gly Ala Gly Arg Glu Glu Asn Ala Gly Ala Glu 
    50                  55                  60                  


Ala Ala Gln Ser Leu Ser His Glu Gln Pro Gln Asp Ser Ser Glu Ala 
65                  70                  75                  80  


Gly Ala Ala Ala Leu Pro Arg Gly Pro Glu Glu Pro Glu Arg Pro Val 
                85                  90                  95      


Arg Arg Ser Phe Gln Ile Pro Arg Lys Ser Arg Glu Lys Lys Ala Leu 
            100                 105                 110         


Phe Gln Pro Leu Thr Pro Gly Ser Arg Glu Phe Glu Asp Val Val Asn 
        115                 120                 125             


Ile Leu His Ser Ser Tyr Leu Glu Pro Thr Ser Val Thr Asn Phe Asn 
    130                 135                 140                 


Tyr Arg Arg Ala Cys Leu Val His Asn Glu Leu Leu Glu Lys Glu Phe 
145                 150                 155                 160 


Thr Glu Lys Arg Arg Glu Leu Lys Phe Asp Gly Arg Leu Asp Lys Glu 
                165                 170                 175     


Leu Ser Glu Ser Tyr Ala Phe Leu Met Val Asp Arg Tyr Gln Val Gln 
            180                 185                 190         


Thr Ile Cys Glu Lys Gly Leu His Val Gly Gln Ser Lys Ile Thr Ile 
        195                 200                 205             


Leu Gly Ser Pro Ser Met Gly Val Tyr Leu Ser Arg Tyr Ala Asp Leu 
    210                 215                 220                 


Leu Gln Ala Asn Pro Leu Asp Thr Gly Ala Met Gly Asp Val Val Ile 
225                 230                 235                 240 


Phe Lys Ile Met Lys Gly Lys Ile Lys Ser Ile Tyr Asp Pro Met Gly 
                245                 250                 255     


Val Lys Ser Leu Glu Ser Met Leu Asn Lys Ser Ala Leu Asp Pro Thr 
            260                 265                 270         


Pro Lys His Glu Cys His Val Ser Lys Asn Ala Asn Arg Ile Thr Ser 
        275                 280                 285             


Leu Leu Ala Tyr Arg Ala Tyr Glu Leu Thr Gln Tyr Tyr Phe Tyr Glu 
    290                 295                 300                 


Tyr Gly Phe Asp Glu Leu Arg Arg Arg Pro Arg His Val Cys Pro Tyr 
305                 310                 315                 320 


Ala Val Val Ser Phe Thr Tyr Lys Asp Asp Ile Gln Thr Pro Lys Phe 
                325                 330                 335     


Val Pro Ser Ser Arg Ser Asn Ser Phe Asn Thr Asp Arg Asn Ile Asp 
            340                 345                 350         


Lys Tyr Asn Tyr Thr Leu Trp Lys Gly Gln Leu Leu Asn Lys Gly Lys 
        355                 360                 365             


Leu Leu Cys Tyr Ile Ser Leu Arg Ser Ala Thr Arg Ala Phe Leu Pro 
    370                 375                 380                 


Ile Lys Leu Pro Glu Lys Leu Asp Val Glu Thr Val Met Ser Ile Asp 
385                 390                 395                 400 


His Leu Lys Gln Lys Ile Pro Pro Ala Leu Phe Tyr Lys Glu Thr Tyr 
                405                 410                 415     


Leu Gly Pro Asn Glu Val Leu Lys Asn Gly Met Tyr Cys Ser Leu Tyr 
            420                 425                 430         


Glu Val Val Glu Lys Thr Arg Ile Gly Ser Asn Met Glu Ser Leu Leu 
        435                 440                 445             


Gln Lys Leu Asp Arg Glu Lys Leu Val Leu Val Lys Pro Leu Gly Asp 
    450                 455                 460                 


Arg Gly Tyr Leu Phe Leu Leu Ser Pro Tyr Gln Met Val Pro Pro Tyr 
465                 470                 475                 480 


Glu Tyr Gln Thr Ala Lys Ser Arg Val Leu His Ala Leu Phe Leu Phe 
                485                 490                 495     


Gln Glu Pro Arg Ser Ile Val Thr Ser Gln Lys Gly Ser Thr Asn Ala 
            500                 505                 510         


Ala Pro Gln Glu Arg His Glu Ser Met Pro Asp Val Leu Lys Ile Ala 
        515                 520                 525             


Gln Phe Leu Gln Phe Ser Leu Ile Gln Cys Arg Lys Glu Phe Lys Asn 
    530                 535                 540                 


Ile Ser Ala Ile Asn Phe His Ser Val Val Glu Lys Tyr Val Ser Glu 
545                 550                 555                 560 


Phe Phe Lys Arg Gly Phe Gly Ser Gly Lys Arg Glu Phe Ile Met Phe 
                565                 570                 575     


Pro Tyr Asp Ser Arg Leu Asp Asp Lys Lys Phe Leu Tyr Ser Ala Pro 
            580                 585                 590         


Arg Asn Lys Ser His Ile Asp Thr Cys Leu His Ala Tyr Ile Phe Arg 
        595                 600                 605             


Pro Glu Val Tyr Gln Leu Pro Ile Cys Lys Leu Lys Glu Leu Phe Glu 
    610                 615                 620                 


Glu Asn Arg Lys Leu Gln Gln Phe Ser Pro Leu Ser Asp Tyr Glu Gly 
625                 630                 635                 640 


Gln Glu Glu Glu Met Asn Gly Thr Lys Met Lys Phe Gly Lys Arg Asn 
                645                 650                 655     


Asn Ser Arg Gly Glu Ala Ile Ile Ser Gly Lys Gln Arg Ser Ser His 
            660                 665                 670         


Ser Leu Asp Tyr Asp Lys Asp Arg Val Lys Glu Leu Ile Asn Leu Ile 
        675                 680                 685             


Gln Cys Arg Lys Lys Ser Val Gly Gly Asp Ser Asp Thr Glu Asp Met 
    690                 695                 700                 


Arg Ser Lys Thr Val Leu Lys Arg Lys Leu Glu Asp Leu Pro Glu Asn 
705                 710                 715                 720 


Met Arg Lys Leu Ala Lys Thr Ser Asn Leu Ser Glu Asn Cys His Leu 
                725                 730                 735     


Tyr Glu Glu Ser Pro Gln Pro Ile Gly Ser Leu Gly His Asp Ala Asp 
            740                 745                 750         


Leu Arg Arg Gln Gln Gln Asp Thr Cys Asn Ser Gly Ile Ala Asp Ile 
        755                 760                 765             


His Arg Leu Phe Asn Trp Leu Ser Glu Thr Leu Ala Asn Ala Arg His 
    770                 775                 780                 


Ser Asp Ala Ser Leu Thr Asp Thr Val Asn Lys Ala Leu Gly Leu Ser 
785                 790                 795                 800 


Thr Asp Asp Ala Tyr Glu Glu Leu Arg Gln Lys His Glu Tyr Glu Leu 
                805                 810                 815     


Asn Ser Thr Pro Asp Lys Lys Asp Tyr Glu Gln Pro Thr Cys Ala Lys 
            820                 825                 830         


Val Glu Asn Ala Gln Phe Lys Gly Thr Gln Ser Leu Leu Leu Glu Val 
        835                 840                 845             


Asp Ala Thr Ser Lys Tyr Ser Val Ala Ile Ser Thr Ser Glu Val Gly 
    850                 855                 860                 


Thr Asp His Lys Leu His Leu Lys Glu Asp Pro Asn Leu Ile Ser Val 
865                 870                 875                 880 


Asn Asn Phe Glu Asp Cys Ser Leu Cys Pro Ser Val Pro Ile Glu His 
                885                 890                 895     


Gly Phe Arg Arg Gln Gln Ser Lys Ser Asn Asn Val Glu Glu Thr Glu 
            900                 905                 910         


Ile His Trp Lys Leu Ile Pro Ile Thr Gly Gly Asn Ala Arg Ser Pro 
        915                 920                 925             


Glu Asp Gln Leu Gly Lys His Gly Glu Lys Gln Thr Pro Gly Met Lys 
    930                 935                 940                 


Ser Pro Glu Glu Gln Leu Val Cys Val Pro Pro Gln Glu Ala Phe Pro 
945                 950                 955                 960 


Asn Asp Pro Arg Val Ile Asn Arg Gln Arg Ser Ser Asp Tyr Gln Phe 
                965                 970                 975     


Pro Ser Ser Pro Phe Thr Asp Thr Leu Lys Gly Thr Thr Glu Asp Asp 
            980                 985                 990         


Val Leu Thr Gly Gln Val Glu Glu  Gln Cys Val Pro Ala  Ala Glu Ala 
        995                 1000                 1005             


Glu Pro  Pro Ala Val Ser Glu  Thr Thr Glu Arg Thr  Val Leu Gly 
    1010                 1015                 1020             


Glu Tyr  Asn Leu Phe Ser Arg  Lys Ile Glu Glu Ile  Leu Lys Gln 
    1025                 1030                 1035             


Lys Asn  Val Ser Tyr Val Ser  Thr Val Ser Thr Pro  Ile Phe Ser 
    1040                 1045                 1050             


Thr Gln  Glu Lys Met Lys Arg  Leu Ser Glu Phe Ile  Tyr Ser Lys 
    1055                 1060                 1065             


Thr Ser  Lys Ala Gly Val Gln  Glu Phe Val Asp Gly  Leu His Glu 
    1070                 1075                 1080             


Lys Leu  Asn Thr Ile Ile Ile  Lys Ala Ser Ala Lys  Gly Gly Asn 
    1085                 1090                 1095             


Leu Pro  Pro Val Ser Pro Asn  Asp Ser Gly Ala Lys  Ile Ala Ser 
    1100                 1105                 1110             


Asn Pro  Leu Glu Arg His Val  Ile Pro Val Ser Ser  Ser Asp Phe 
    1115                 1120                 1125             


Asn Asn  Lys His Leu Leu Glu  Pro Leu Cys Ser Asp  Pro Leu Lys 
    1130                 1135                 1140             


Asp Thr  Asn Ser Asp Glu Gln  His Ser Thr Ser Ala  Leu Thr Glu 
    1145                 1150                 1155             


Val Glu  Met Asn Gln Pro Gln  His Ala Thr Glu Leu  Met Val Thr 
    1160                 1165                 1170             


Ser Asp  His Ile Val Pro Gly  Asp Met Ala Arg Glu  Pro Val Glu 
    1175                 1180                 1185             


Glu Thr  Thr Lys Ser Pro Ser  Asp Val Asn Ile Ser  Ala Gln Pro 
    1190                 1195                 1200             


Ala Leu  Ser Asn Phe Ile Ser  Gln Leu Glu Pro Glu  Val Phe Asn 
    1205                 1210                 1215             


Ser Leu  Val Lys Ile Met Lys  Asp Val Gln Lys Asn  Thr Val Lys 
    1220                 1225                 1230             


Phe Tyr  Ile His Glu Glu Glu  Glu Ser Val Leu Cys  Lys Glu Ile 
    1235                 1240                 1245             


Lys Glu  Tyr Leu Ile Lys Leu  Gly Asn Thr Glu Cys  His Pro Glu 
    1250                 1255                 1260             


Gln Phe  Leu Glu Arg Arg Ser  Lys Leu Asp Lys Leu  Leu Ile Ile 
    1265                 1270                 1275             


Ile Gln  Asn Glu Asp Ile Ala  Gly Phe Ile His Lys  Ile Pro Gly 
    1280                 1285                 1290             


Leu Val  Thr Leu Lys Lys Leu  Pro Cys Val Ser Phe  Ala Gly Val 
    1295                 1300                 1305             


Asp Ser  Leu Asp Asp Val Lys  Asn His Thr Tyr Asn  Glu Leu Phe 
    1310                 1315                 1320             


Val Ser  Gly Gly Phe Ile Val  Ser Asp Glu Ser Ile  Leu Asn Pro 
    1325                 1330                 1335             


Glu Val  Val Thr Val Glu Asn  Leu Lys Asn Phe Leu  Thr Phe Leu 
    1340                 1345                 1350             


Glu Glu  Leu Ser Thr Pro Glu  Gly Lys Trp Gln Trp  Lys Val His 
    1355                 1360                 1365             


Cys Lys  Phe Gln Lys Lys Leu  Lys Glu Leu Gly Arg  Leu Asn Ala 
    1370                 1375                 1380             


Lys Ala  Leu Ser Leu Leu Thr  Leu Leu Asn Val Tyr  Gln Lys Lys 
    1385                 1390                 1395             


His Leu  Val Glu Ile Leu Ser  Tyr His Asn Cys Asp  Ser Gln Thr 
    1400                 1405                 1410             


Arg Asn  Ala Pro Glu Leu Asp  Cys Leu Ile Arg Leu  Gln Ala Gln 
    1415                 1420                 1425             


Asn Ile  Gln Gln Arg His Ile  Val Phe Leu Thr Glu  Lys Asn Ile 
    1430                 1435                 1440             


Lys Met  Leu Ser Ser Tyr Thr  Asp Asn Gly Ile Val  Val Ala Thr 
    1445                 1450                 1455             


Ala Glu  Asp Phe Met Gln Asn  Phe Lys Asn Leu Val  Gly Tyr His 
    1460                 1465                 1470             


Asn Ser  Ile Thr Glu Glu Asn  Leu Pro Gln Leu Gly  Ala Asn Glu 
    1475                 1480                 1485             


Asn Leu  Glu Ser Gln Ser Asp  Ala Val Leu Thr Leu  Thr Pro Leu 
    1490                 1495                 1500             


Glu Leu  Gly Val Gly Ile Ser  Gln His 
    1505                 1510         


<210>  3106
<211>  435
<212>  PRT
<213>  homo sapiens

<400>  3106

Met Ile Trp Lys Arg Ser Ala Val Leu Arg Phe Tyr Ser Val Cys Gly 
1               5                   10                  15      


Leu Leu Leu Gln Gly Ser Gln Gly Gln Phe Pro Leu Thr Gln Asn Val 
            20                  25                  30          


Thr Val Val Glu Gly Gly Thr Ala Ile Leu Thr Cys Arg Val Asp Gln 
        35                  40                  45              


Asn Asp Asn Thr Ser Leu Gln Trp Ser Asn Pro Ala Gln Gln Thr Leu 
    50                  55                  60                  


Tyr Phe Asp Asp Lys Lys Ala Leu Arg Asp Asn Arg Ile Glu Leu Val 
65                  70                  75                  80  


Arg Ala Ser Trp His Glu Leu Ser Ile Ser Val Ser Asp Val Ser Leu 
                85                  90                  95      


Ser Asp Glu Gly Gln Tyr Thr Cys Ser Leu Phe Thr Met Pro Val Lys 
            100                 105                 110         


Thr Ser Lys Ala Tyr Leu Thr Val Leu Gly Val Pro Glu Lys Pro Gln 
        115                 120                 125             


Ile Ser Gly Phe Ser Ser Pro Val Met Glu Gly Asp Leu Met Gln Leu 
    130                 135                 140                 


Thr Cys Lys Thr Ser Gly Ser Lys Pro Ala Ala Asp Ile Arg Trp Phe 
145                 150                 155                 160 


Lys Asn Asp Lys Glu Ile Lys Asp Val Lys Tyr Leu Lys Glu Glu Asp 
                165                 170                 175     


Ala Asn Arg Lys Thr Phe Thr Val Ser Ser Thr Leu Asp Phe Arg Val 
            180                 185                 190         


Asp Arg Ser Asp Asp Gly Val Ala Val Ile Cys Arg Val Asp His Glu 
        195                 200                 205             


Ser Leu Asn Ala Thr Pro Gln Val Ala Met Gln Val Leu Glu Ile His 
    210                 215                 220                 


Tyr Thr Pro Ser Val Lys Ile Ile Pro Ser Thr Pro Phe Pro Gln Glu 
225                 230                 235                 240 


Gly Gln Pro Leu Ile Leu Thr Cys Glu Ser Lys Gly Lys Pro Leu Pro 
                245                 250                 255     


Glu Pro Val Leu Trp Thr Lys Asp Gly Gly Glu Leu Pro Asp Pro Asp 
            260                 265                 270         


Arg Met Val Val Ser Gly Arg Glu Leu Asn Ile Leu Phe Leu Asn Lys 
        275                 280                 285             


Thr Asp Asn Gly Thr Tyr Arg Cys Glu Ala Thr Asn Thr Ile Gly Gln 
    290                 295                 300                 


Ser Ser Ala Glu Tyr Val Leu Ile Val His Asp Val Pro Asn Thr Leu 
305                 310                 315                 320 


Leu Pro Thr Thr Ile Ile Pro Ser Leu Thr Thr Ala Thr Val Thr Thr 
                325                 330                 335     


Thr Val Ala Ile Thr Thr Ser Pro Thr Thr Ser Ala Thr Thr Ser Ser 
            340                 345                 350         


Ile Arg Asp Pro Asn Ala Leu Ala Gly Gln Asn Gly Pro Asp His Ala 
        355                 360                 365             


Leu Ile Gly Gly Ile Val Ala Val Val Val Phe Val Thr Leu Cys Ser 
    370                 375                 380                 


Ile Phe Leu Leu Gly Arg Tyr Leu Ala Arg His Lys Gly Thr Tyr Leu 
385                 390                 395                 400 


Thr Asn Glu Ala Lys Gly Ala Glu Asp Ala Pro Asp Ala Asp Thr Ala 
                405                 410                 415     


Ile Ile Asn Ala Glu Gly Ser Gln Val Asn Ala Glu Glu Lys Lys Glu 
            420                 425                 430         


Tyr Phe Ile 
        435 


<210>  3107
<211>  377
<212>  PRT
<213>  homo sapiens

<400>  3107

Met Arg Leu Ser Val Arg Arg Val Leu Leu Ala Ala Gly Cys Ala Leu 
1               5                   10                  15      


Val Leu Val Leu Ala Val Gln Leu Gly Gln Gln Val Leu Glu Cys Arg 
            20                  25                  30          


Ala Val Leu Ala Gly Leu Arg Ser Pro Arg Gly Ala Met Arg Pro Glu 
        35                  40                  45              


Gln Glu Glu Leu Val Met Val Gly Thr Asn His Val Glu Tyr Arg Tyr 
    50                  55                  60                  


Gly Lys Ala Met Pro Leu Ile Phe Val Gly Gly Val Pro Arg Ser Gly 
65                  70                  75                  80  


Thr Thr Leu Met Arg Ala Met Leu Asp Ala His Pro Glu Val Arg Cys 
                85                  90                  95      


Gly Glu Glu Thr Arg Ile Ile Pro Arg Val Leu Ala Met Arg Gln Ala 
            100                 105                 110         


Trp Ser Lys Ser Gly Arg Glu Lys Leu Arg Leu Asp Glu Ala Gly Val 
        115                 120                 125             


Thr Asp Glu Val Leu Asp Ala Ala Met Gln Ala Phe Ile Leu Glu Val 
    130                 135                 140                 


Ile Ala Lys His Gly Glu Pro Ala Arg Val Leu Cys Asn Lys Asp Pro 
145                 150                 155                 160 


Phe Thr Leu Lys Ser Ser Val Tyr Leu Ser Arg Leu Phe Pro Asn Ser 
                165                 170                 175     


Lys Phe Leu Leu Met Val Arg Asp Gly Arg Ala Ser Val His Ser Met 
            180                 185                 190         


Ile Thr Arg Lys Val Thr Ile Ala Gly Phe Asp Leu Ser Ser Tyr Arg 
        195                 200                 205             


Asp Cys Leu Thr Lys Trp Asn Lys Ala Ile Glu Val Met Tyr Ala Gln 
    210                 215                 220                 


Cys Met Glu Val Gly Lys Glu Lys Cys Leu Pro Val Tyr Tyr Glu Gln 
225                 230                 235                 240 


Leu Val Leu His Pro Arg Arg Ser Leu Lys Leu Ile Leu Asp Phe Leu 
                245                 250                 255     


Gly Ile Ala Trp Ser Asp Ala Val Leu His His Glu Asp Leu Ile Gly 
            260                 265                 270         


Lys Pro Gly Gly Val Ser Leu Ser Lys Ile Glu Arg Ser Thr Asp Gln 
        275                 280                 285             


Val Ile Lys Pro Val Asn Leu Glu Ala Leu Ser Lys Trp Thr Gly His 
    290                 295                 300                 


Ile Pro Gly Asp Val Val Arg Asp Met Ala Gln Ile Ala Pro Met Leu 
305                 310                 315                 320 


Ala Gln Leu Gly Tyr Asp Pro Tyr Ala Asn Pro Pro Asn Tyr Gly Asn 
                325                 330                 335     


Pro Asp Pro Phe Val Ile Asn Asn Thr Gln Arg Val Leu Lys Gly Asp 
            340                 345                 350         


Tyr Lys Thr Pro Ala Asn Leu Lys Gly Tyr Phe Gln Val Asn Gln Asn 
        355                 360                 365             


Ser Thr Ser Ser His Leu Gly Ser Ser 
    370                 375         


<210>  3108
<211>  377
<212>  PRT
<213>  homo sapiens

<400>  3108

Met Arg Leu Ser Val Arg Arg Val Leu Leu Ala Ala Gly Cys Ala Leu 
1               5                   10                  15      


Val Leu Val Leu Ala Val Gln Leu Gly Gln Gln Val Leu Glu Cys Arg 
            20                  25                  30          


Ala Val Leu Ala Gly Leu Arg Ser Pro Arg Gly Ala Met Arg Pro Glu 
        35                  40                  45              


Gln Glu Glu Leu Val Met Val Gly Thr Asn His Val Glu Tyr Arg Tyr 
    50                  55                  60                  


Gly Lys Ala Met Pro Leu Ile Phe Val Gly Gly Val Pro Arg Ser Gly 
65                  70                  75                  80  


Thr Thr Leu Met Arg Ala Met Leu Asp Ala His Pro Glu Val Arg Cys 
                85                  90                  95      


Gly Glu Glu Thr Arg Ile Ile Pro Arg Val Leu Ala Met Arg Gln Ala 
            100                 105                 110         


Trp Ser Lys Ser Gly Arg Glu Lys Leu Arg Leu Asp Glu Ala Gly Val 
        115                 120                 125             


Thr Asp Glu Val Leu Asp Ala Ala Met Gln Ala Phe Ile Leu Glu Val 
    130                 135                 140                 


Ile Ala Lys His Gly Glu Pro Ala Arg Val Leu Cys Asn Lys Asp Pro 
145                 150                 155                 160 


Phe Thr Leu Lys Ser Ser Val Tyr Leu Ser Arg Leu Phe Pro Asn Ser 
                165                 170                 175     


Lys Phe Leu Leu Met Val Arg Asp Gly Arg Ala Ser Val His Ser Met 
            180                 185                 190         


Ile Thr Arg Lys Val Thr Ile Ala Gly Phe Asp Leu Ser Ser Tyr Arg 
        195                 200                 205             


Asp Cys Leu Thr Lys Trp Asn Lys Ala Ile Glu Val Met Tyr Ala Gln 
    210                 215                 220                 


Cys Met Glu Val Gly Lys Glu Lys Cys Leu Pro Val Tyr Tyr Glu Gln 
225                 230                 235                 240 


Leu Val Leu His Pro Arg Arg Ser Leu Lys Leu Ile Leu Asp Phe Leu 
                245                 250                 255     


Gly Ile Ala Trp Ser Asp Ala Val Leu His His Glu Asp Leu Ile Gly 
            260                 265                 270         


Lys Pro Gly Gly Val Ser Leu Ser Lys Ile Glu Arg Ser Thr Asp Gln 
        275                 280                 285             


Val Ile Lys Pro Val Asn Leu Glu Ala Leu Ser Lys Trp Thr Gly His 
    290                 295                 300                 


Ile Pro Gly Asp Val Val Arg Asp Met Ala Gln Ile Ala Pro Met Leu 
305                 310                 315                 320 


Ala Gln Leu Gly Tyr Asp Pro Tyr Ala Asn Pro Pro Asn Tyr Gly Asn 
                325                 330                 335     


Pro Asp Pro Phe Val Ile Asn Asn Thr Gln Arg Val Leu Lys Gly Asp 
            340                 345                 350         


Tyr Lys Thr Pro Ala Asn Leu Lys Gly Tyr Phe Gln Val Asn Gln Asn 
        355                 360                 365             


Ser Thr Ser Ser His Leu Gly Ser Ser 
    370                 375         


<210>  3109
<211>  282
<212>  PRT
<213>  homo sapiens

<400>  3109

Met Ser Asp Val Glu Glu Asn Asn Phe Glu Gly Arg Glu Ser Arg Ser 
1               5                   10                  15      


Gln Ser Lys Ser Pro Thr Gly Thr Pro Ala Arg Val Lys Ser Glu Ser 
            20                  25                  30          


Arg Ser Gly Ser Arg Ser Pro Ser Arg Val Ser Lys His Ser Glu Ser 
        35                  40                  45              


His Ser Arg Ser Arg Ser Lys Ser Arg Ser Arg Ser Arg Arg His Ser 
    50                  55                  60                  


His Arg Arg Tyr Thr Arg Ser Arg Ser His Ser His Ser His Arg Arg 
65                  70                  75                  80  


Arg Ser Arg Ser Arg Ser Tyr Thr Pro Glu Tyr Arg Arg Arg Arg Ser 
                85                  90                  95      


Arg Ser His Ser Pro Met Ser Asn Arg Arg Arg His Thr Gly Ser Arg 
            100                 105                 110         


Ala Asn Pro Asp Pro Asn Thr Cys Leu Gly Val Phe Gly Leu Ser Leu 
        115                 120                 125             


Tyr Thr Thr Glu Arg Asp Leu Arg Glu Val Phe Ser Arg Tyr Gly Pro 
    130                 135                 140                 


Leu Ser Gly Val Asn Val Val Tyr Asp Gln Arg Thr Gly Arg Ser Arg 
145                 150                 155                 160 


Gly Phe Ala Phe Val Tyr Phe Glu Arg Ile Asp Asp Ser Lys Glu Ala 
                165                 170                 175     


Met Glu Arg Ala Asn Gly Met Glu Leu Asp Gly Arg Arg Ile Arg Val 
            180                 185                 190         


Asp Tyr Ser Ile Thr Lys Arg Ala His Thr Pro Thr Pro Gly Ile Tyr 
        195                 200                 205             


Met Gly Arg Pro Thr His Ser Gly Gly Gly Gly Gly Gly Gly Gly Gly 
    210                 215                 220                 


Gly Gly Gly Gly Gly Gly Gly Arg Arg Arg Asp Ser Tyr Tyr Asp Arg 
225                 230                 235                 240 


Gly Tyr Asp Arg Gly Tyr Asp Arg Tyr Glu Asp Tyr Asp Tyr Arg Tyr 
                245                 250                 255     


Arg Arg Arg Ser Pro Ser Pro Tyr Tyr Ser Arg Tyr Arg Ser Arg Ser 
            260                 265                 270         


Arg Ser Arg Ser Tyr Ser Pro Arg Arg Tyr 
        275                 280         


<210>  3110
<211>  372
<212>  PRT
<213>  homo sapiens

<400>  3110

Met Arg Val Gly Pro Val Arg Ser Ala Met Ser Gly Ala Ser Gln Pro 
1               5                   10                  15      


Arg Gly Pro Ala Leu Leu Phe Pro Ala Thr Arg Gly Val Pro Ala Lys 
            20                  25                  30          


Arg Leu Leu Asp Ala Asp Asp Ala Ala Ala Val Ala Ala Lys Cys Pro 
        35                  40                  45              


Arg Leu Ser Glu Cys Ser Ser Pro Pro Asp Tyr Leu Ser Pro Pro Gly 
    50                  55                  60                  


Ser Pro Cys Ser Pro Gln Pro Pro Pro Ala Ala Pro Gly Ala Gly Gly 
65                  70                  75                  80  


Gly Ser Gly Ser Ala Pro Gly Pro Ser Arg Ile Ala Asp Tyr Leu Leu 
                85                  90                  95      


Leu Pro Leu Ala Glu Arg Glu His Val Ser Arg Ala Leu Cys Ile His 
            100                 105                 110         


Thr Gly Arg Glu Leu Arg Cys Lys Val Phe Pro Ile Lys His Tyr Gln 
        115                 120                 125             


Asp Lys Ile Arg Pro Tyr Ile Gln Leu Pro Ser His Ser Asn Ile Thr 
    130                 135                 140                 


Gly Ile Val Glu Val Ile Leu Gly Glu Thr Lys Ala Tyr Val Phe Phe 
145                 150                 155                 160 


Glu Lys Asp Phe Gly Asp Met His Ser Tyr Val Arg Ser Arg Lys Arg 
                165                 170                 175     


Leu Arg Glu Glu Glu Ala Ala Arg Leu Phe Lys Gln Ile Val Ser Ala 
            180                 185                 190         


Val Ala His Cys His Gln Ser Ala Ile Val Leu Gly Asp Leu Lys Leu 
        195                 200                 205             


Arg Lys Phe Val Phe Ser Thr Glu Glu Arg Thr Gln Leu Arg Leu Glu 
    210                 215                 220                 


Ser Leu Glu Asp Thr His Ile Met Lys Gly Glu Asp Asp Ala Leu Ser 
225                 230                 235                 240 


Asp Lys His Gly Cys Pro Ala Tyr Val Ser Pro Glu Ile Leu Asn Thr 
                245                 250                 255     


Thr Gly Thr Tyr Ser Gly Lys Ala Ala Asp Val Trp Ser Leu Gly Val 
            260                 265                 270         


Met Leu Tyr Thr Leu Leu Val Gly Arg Tyr Pro Phe His Asp Ser Asp 
        275                 280                 285             


Pro Ser Ala Leu Phe Ser Lys Ile Arg Arg Gly Gln Phe Cys Ile Pro 
    290                 295                 300                 


Glu His Ile Ser Pro Lys Ala Arg Cys Leu Ile Arg Ser Leu Leu Arg 
305                 310                 315                 320 


Arg Glu Pro Ser Glu Arg Leu Thr Ala Pro Glu Ile Leu Leu His Pro 
                325                 330                 335     


Trp Phe Glu Ser Val Leu Glu Pro Gly Tyr Ile Asp Ser Glu Ile Gly 
            340                 345                 350         


Thr Ser Asp Gln Ile Val Pro Glu Tyr Gln Glu Asp Ser Asp Ile Ser 
        355                 360                 365             


Ser Phe Phe Cys 
    370         


<210>  3111
<211>  1076
<212>  PRT
<213>  homo sapiens

<400>  3111

Met Ile Ala Val Ser Phe Lys Cys Arg Cys Gln Ile Leu Arg Arg Leu 
1               5                   10                  15      


Thr Lys Asp Glu Ser Pro Tyr Thr Lys Ser Ala Ser Gln Thr Lys Pro 
            20                  25                  30          


Pro Asp Gly Ala Leu Ala Val Arg Arg Gln Ser Ile Pro Glu Glu Phe 
        35                  40                  45              


Lys Gly Ser Thr Val Val Glu Leu Met Lys Lys Glu Gly Thr Thr Leu 
    50                  55                  60                  


Gly Leu Thr Val Ser Gly Gly Ile Asp Lys Asp Gly Lys Pro Arg Val 
65                  70                  75                  80  


Ser Asn Leu Arg Gln Gly Gly Ile Ala Ala Arg Ser Asp Gln Leu Asp 
                85                  90                  95      


Val Gly Asp Tyr Ile Lys Ala Val Asn Gly Ile Asn Leu Ala Lys Phe 
            100                 105                 110         


Arg His Asp Glu Ile Ile Ser Leu Leu Lys Asn Val Gly Glu Arg Val 
        115                 120                 125             


Val Leu Glu Val Glu Tyr Glu Leu Pro Pro Val Ser Val Gln Gly Ser 
    130                 135                 140                 


Ser Val Ile Phe Arg Thr Val Glu Val Thr Leu His Lys Glu Gly Asn 
145                 150                 155                 160 


Thr Phe Gly Phe Val Ile Arg Gly Gly Ala His Asp Asp Arg Asn Lys 
                165                 170                 175     


Ser Arg Pro Val Val Ile Thr Cys Val Arg Pro Gly Gly Pro Ala Asp 
            180                 185                 190         


Arg Glu Gly Thr Ile Lys Pro Gly Asp Arg Leu Leu Ser Val Asp Gly 
        195                 200                 205             


Ile Arg Leu Leu Gly Thr Thr His Ala Glu Ala Met Ser Ile Leu Lys 
    210                 215                 220                 


Gln Cys Gly Gln Glu Ala Ala Leu Leu Ile Glu Tyr Asp Val Ser Val 
225                 230                 235                 240 


Met Asp Ser Val Ala Thr Ala Ser Gly Pro Leu Leu Val Glu Val Ala 
                245                 250                 255     


Lys Thr Pro Gly Ala Ser Leu Gly Val Ala Leu Thr Thr Ser Met Cys 
            260                 265                 270         


Cys Asn Lys Gln Val Ile Val Ile Asp Lys Ile Lys Ser Ala Ser Ile 
        275                 280                 285             


Ala Asp Arg Cys Gly Ala Leu His Val Gly Asp His Ile Leu Ser Ile 
    290                 295                 300                 


Asp Gly Thr Ser Met Glu Tyr Cys Thr Leu Ala Glu Ala Thr Gln Phe 
305                 310                 315                 320 


Leu Ala Asn Thr Thr Asp Gln Val Lys Leu Glu Ile Leu Pro His His 
                325                 330                 335     


Gln Thr Arg Leu Ala Leu Lys Gly Pro Asp His Ala Ala Leu Val Ser 
            340                 345                 350         


Ser Ser Phe Ser Pro Thr Ser Met Ser Ala Tyr Ser Leu Ser Ser Leu 
        355                 360                 365             


Asn Met Gly Thr Leu Pro Arg Ser Leu Tyr Ser Thr Ser Pro Arg Gly 
    370                 375                 380                 


Thr Met Met Arg Arg Arg Leu Lys Lys Lys Asp Phe Lys Ser Ser Leu 
385                 390                 395                 400 


Ser Leu Ala Ser Ser Thr Val Gly Leu Ala Gly Gln Val Val His Thr 
                405                 410                 415     


Glu Thr Thr Glu Val Val Leu Thr Ala Asp Pro Val Thr Gly Phe Gly 
            420                 425                 430         


Ile Gln Leu Gln Gly Ser Val Phe Ala Thr Glu Thr Leu Ser Ser Pro 
        435                 440                 445             


Pro Leu Ile Ser Tyr Ile Glu Ala Asp Ser Pro Ala Glu Arg Cys Gly 
    450                 455                 460                 


Val Leu Gln Ile Gly Asp Arg Val Met Ala Ile Asn Gly Ile Pro Thr 
465                 470                 475                 480 


Glu Asp Ser Thr Phe Glu Glu Ala Ser Gln Leu Leu Arg Asp Ser Ser 
                485                 490                 495     


Ile Thr Ser Lys Val Thr Leu Glu Ile Glu Phe Asp Val Ala Glu Ser 
            500                 505                 510         


Val Ile Pro Ser Ser Gly Thr Phe His Val Lys Leu Pro Lys Lys His 
        515                 520                 525             


Asn Val Glu Leu Gly Ile Thr Ile Ser Ser Pro Ser Ser Arg Lys Pro 
    530                 535                 540                 


Gly Asp Pro Leu Val Ile Ser Asp Ile Lys Lys Gly Ser Val Ala His 
545                 550                 555                 560 


Arg Thr Gly Thr Leu Glu Leu Gly Asp Lys Leu Leu Ala Ile Asp Asn 
                565                 570                 575     


Ile Arg Leu Asp Asn Cys Ser Met Glu Asp Ala Val Gln Ile Leu Gln 
            580                 585                 590         


Gln Cys Glu Asp Leu Val Lys Leu Lys Ile Arg Lys Asp Glu Asp Asn 
        595                 600                 605             


Ser Asp Glu Gln Glu Ser Ser Gly Ala Ile Ile Tyr Thr Val Glu Leu 
    610                 615                 620                 


Lys Arg Tyr Gly Gly Pro Leu Gly Ile Thr Ile Ser Gly Thr Glu Glu 
625                 630                 635                 640 


Pro Phe Asp Pro Ile Ile Ile Ser Ser Leu Thr Lys Gly Gly Leu Ala 
                645                 650                 655     


Glu Arg Thr Gly Ala Ile His Ile Gly Asp Arg Ile Leu Ala Ile Asn 
            660                 665                 670         


Ser Ser Ser Leu Lys Gly Lys Pro Leu Ser Glu Ala Ile His Leu Leu 
        675                 680                 685             


Gln Met Ala Gly Glu Thr Val Thr Leu Lys Ile Lys Lys Gln Thr Asp 
    690                 695                 700                 


Ala Gln Ser Ala Ser Ser Pro Lys Lys Phe Pro Ile Ser Ser His Leu 
705                 710                 715                 720 


Ser Asp Leu Gly Asp Val Glu Glu Asp Ser Ser Pro Ala Gln Lys Pro 
                725                 730                 735     


Gly Lys Leu Ser Asp Met Tyr Pro Ser Thr Val Pro Ser Val Asp Ser 
            740                 745                 750         


Ala Val Asp Ser Trp Asp Gly Ser Ala Ile Asp Thr Ser Tyr Gly Thr 
        755                 760                 765             


Gln Gly Thr Ser Phe Gln Ala Ser Gly Tyr Asn Phe Asn Thr Tyr Asp 
    770                 775                 780                 


Trp Arg Ser Pro Lys Gln Arg Gly Ser Leu Ser Pro Val Thr Lys Pro 
785                 790                 795                 800 


Arg Ser Gln Thr Tyr Pro Asp Val Gly Leu Ser Tyr Glu Asp Trp Asp 
                805                 810                 815     


Arg Ser Thr Ala Ser Gly Phe Ala Gly Ala Ala Asp Ser Ala Glu Thr 
            820                 825                 830         


Glu Gln Glu Glu Asn Phe Trp Ser Gln Ala Leu Glu Asp Leu Glu Thr 
        835                 840                 845             


Cys Gly Gln Ser Gly Ile Leu Arg Glu Leu Glu Glu Lys Ala Asp Arg 
    850                 855                 860                 


Arg Val Ser Leu Arg Asn Met Thr Leu Leu Ala Thr Ile Met Ser Gly 
865                 870                 875                 880 


Ser Thr Met Ser Leu Asn His Glu Ala Pro Thr Pro Arg Ser Gln Leu 
                885                 890                 895     


Gly Arg Gln Ala Ser Phe Gln Glu Arg Ser Ser Ser Arg Pro His Tyr 
            900                 905                 910         


Ser Gln Thr Thr Arg Ser Asn Thr Leu Pro Ser Asp Val Gly Arg Lys 
        915                 920                 925             


Ser Val Thr Leu Arg Lys Met Lys Gln Glu Ile Lys Glu Ile Met Ser 
    930                 935                 940                 


Pro Thr Pro Val Glu Leu His Lys Val Thr Leu Tyr Lys Asp Ser Asp 
945                 950                 955                 960 


Met Glu Asp Phe Gly Phe Ser Val Ala Asp Gly Leu Leu Glu Lys Gly 
                965                 970                 975     


Val Tyr Val Lys Asn Ile Arg Pro Ala Gly Pro Gly Asp Leu Gly Gly 
            980                 985                 990         


Leu Lys Pro Tyr Asp Arg Leu Leu  Gln Val Asn His Val  Arg Thr Arg 
        995                 1000                 1005             


Asp Phe  Asp Cys Cys Leu Val  Val Pro Leu Ile Ala  Glu Ser Gly 
    1010                 1015                 1020             


Asn Lys  Leu Asp Leu Val Ile  Ser Arg Asn Pro Leu  Ala Ser Gln 
    1025                 1030                 1035             


Lys Ser  Ile Asp Gln Gln Ser  Leu Pro Gly Asp Trp  Ser Glu Gln 
    1040                 1045                 1050             


Asn Ser  Ala Phe Phe Gln Gln  Pro Ser His Gly Gly  Asn Leu Glu 
    1055                 1060                 1065             


Thr Arg  Glu Pro Thr Asn Thr  Leu 
    1070                 1075     


<210>  3112
<211>  498
<212>  PRT
<213>  homo sapiens

<400>  3112

Met Asp Phe Ser Val Lys Val Asp Ile Glu Lys Glu Val Thr Cys Pro 
1               5                   10                  15      


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys Gly His 
            20                  25                  30          


Ser Phe Cys Gln Ala Cys Ile Thr Ala Lys Ile Lys Glu Ser Val Ile 
        35                  40                  45              


Ile Ser Arg Gly Glu Ser Ser Cys Pro Val Cys Gln Thr Arg Phe Gln 
    50                  55                  60                  


Pro Gly Asn Leu Arg Pro Asn Arg His Leu Ala Asn Ile Val Glu Arg 
65                  70                  75                  80  


Val Lys Glu Val Lys Met Ser Pro Gln Glu Gly Gln Lys Arg Asp Val 
                85                  90                  95      


Cys Glu His His Gly Lys Lys Leu Gln Ile Phe Cys Lys Glu Asp Gly 
            100                 105                 110         


Lys Val Ile Cys Trp Val Cys Glu Leu Ser Gln Glu His Gln Gly His 
        115                 120                 125             


Gln Thr Phe Arg Ile Asn Glu Val Val Lys Glu Cys Gln Glu Lys Leu 
    130                 135                 140                 


Gln Val Ala Leu Gln Arg Leu Ile Lys Glu Asp Gln Glu Ala Glu Lys 
145                 150                 155                 160 


Leu Glu Asp Asp Ile Arg Gln Glu Arg Thr Ala Trp Lys Asn Tyr Ile 
                165                 170                 175     


Gln Ile Glu Arg Gln Lys Ile Leu Lys Gly Phe Asn Glu Met Arg Val 
            180                 185                 190         


Ile Leu Asp Asn Glu Glu Gln Arg Glu Leu Gln Lys Leu Glu Glu Gly 
        195                 200                 205             


Glu Val Asn Val Leu Asp Asn Leu Ala Ala Ala Thr Asp Gln Leu Val 
    210                 215                 220                 


Gln Gln Arg Gln Asp Ala Ser Thr Leu Ile Ser Asp Leu Gln Arg Arg 
225                 230                 235                 240 


Leu Arg Gly Ser Ser Val Glu Met Leu Gln Asp Val Ile Asp Val Met 
                245                 250                 255     


Lys Arg Ser Glu Ser Trp Thr Leu Lys Lys Pro Lys Ser Val Ser Lys 
            260                 265                 270         


Lys Leu Lys Ser Val Phe Arg Val Pro Asp Leu Ser Gly Met Leu Gln 
        275                 280                 285             


Val Leu Lys Glu Leu Thr Asp Val Gln Tyr Tyr Trp Val Asp Val Met 
    290                 295                 300                 


Leu Asn Pro Gly Ser Ala Thr Ser Asn Val Ala Ile Ser Val Asp Gln 
305                 310                 315                 320 


Arg Gln Val Lys Thr Val Arg Thr Cys Thr Phe Lys Asn Ser Asn Pro 
                325                 330                 335     


Cys Asp Phe Ser Ala Phe Gly Val Phe Gly Cys Gln Tyr Phe Ser Ser 
            340                 345                 350         


Gly Lys Tyr Tyr Trp Glu Val Asp Val Ser Gly Lys Ile Ala Trp Ile 
        355                 360                 365             


Leu Gly Val His Ser Lys Ile Ser Ser Leu Asn Lys Arg Lys Ser Ser 
    370                 375                 380                 


Gly Phe Ala Phe Asp Pro Ser Val Asn Tyr Ser Lys Val Tyr Ser Arg 
385                 390                 395                 400 


Tyr Arg Pro Gln Tyr Gly Tyr Trp Val Ile Gly Leu Gln Asn Thr Cys 
                405                 410                 415     


Glu Tyr Asn Ala Phe Glu Asp Ser Ser Ser Ser Asp Pro Lys Val Leu 
            420                 425                 430         


Thr Leu Phe Met Ala Val Pro Pro Cys Arg Ile Gly Val Phe Leu Asp 
        435                 440                 445             


Tyr Glu Ala Gly Ile Val Ser Phe Phe Asn Val Thr Asn His Gly Ala 
    450                 455                 460                 


Leu Ile Tyr Lys Phe Ser Gly Cys Arg Phe Ser Arg Pro Ala Tyr Pro 
465                 470                 475                 480 


Tyr Phe Asn Pro Trp Asn Cys Leu Val Pro Met Thr Val Cys Pro Pro 
                485                 490                 495     


Ser Ser 
        


<210>  3113
<211>  4012
<212>  PRT
<213>  homo sapiens

<400>  3113

Met Gly Val Leu Lys Val Trp Leu Gly Leu Ala Leu Ala Leu Ala Glu 
1               5                   10                  15      


Phe Ala Val Leu Pro His His Ser Glu Gly Ala Cys Val Tyr Gln Asp 
            20                  25                  30          


Ser Leu Leu Ala Asp Ala Thr Ile Trp Lys Pro Asp Ser Cys Gln Ser 
        35                  40                  45              


Cys Arg Cys His Gly Asp Ile Val Ile Cys Lys Pro Ala Val Cys Arg 
    50                  55                  60                  


Asn Pro Gln Cys Ala Phe Glu Lys Gly Glu Val Leu Gln Ile Ala Ala 
65                  70                  75                  80  


Asn Gln Cys Cys Pro Glu Cys Val Leu Arg Thr Pro Gly Ser Cys His 
                85                  90                  95      


His Glu Lys Lys Ile His Glu His Gly Thr Glu Trp Ala Ser Ser Pro 
            100                 105                 110         


Cys Ser Val Cys Ser Cys Asn His Gly Glu Val Arg Cys Thr Pro Gln 
        115                 120                 125             


Pro Cys Pro Pro Leu Ser Cys Gly His Gln Glu Leu Ala Phe Ile Pro 
    130                 135                 140                 


Glu Gly Ser Cys Cys Pro Val Cys Val Gly Leu Gly Lys Pro Cys Ser 
145                 150                 155                 160 


Tyr Glu Gly His Val Phe Gln Asp Gly Glu Asp Trp Arg Leu Ser Arg 
                165                 170                 175     


Cys Ala Lys Cys Leu Cys Arg Asn Gly Val Ala Gln Cys Phe Thr Ala 
            180                 185                 190         


Gln Cys Gln Pro Leu Phe Cys Asn Gln Asp Glu Thr Val Val Arg Val 
        195                 200                 205             


Pro Gly Lys Cys Cys Pro Gln Cys Ser Ala Arg Ser Cys Ser Ala Ala 
    210                 215                 220                 


Gly Gln Val Tyr Glu His Gly Glu Gln Trp Ser Glu Asn Ala Cys Thr 
225                 230                 235                 240 


Thr Cys Ile Cys Asp Arg Gly Glu Val Arg Cys His Lys Gln Ala Cys 
                245                 250                 255     


Leu Pro Leu Arg Cys Gly Lys Gly Gln Ser Arg Ala Arg Arg His Gly 
            260                 265                 270         


Gln Cys Cys Glu Glu Cys Val Ser Pro Ala Gly Ser Cys Ser Tyr Asp 
        275                 280                 285             


Gly Val Val Arg Tyr Gln Asp Glu Met Trp Lys Gly Ser Ala Cys Glu 
    290                 295                 300                 


Phe Cys Met Cys Asp His Gly Gln Val Thr Cys Gln Thr Gly Glu Cys 
305                 310                 315                 320 


Ala Lys Val Glu Cys Ala Arg Asp Glu Glu Leu Ile His Leu Asp Gly 
                325                 330                 335     


Lys Cys Cys Pro Glu Cys Ile Ser Arg Asn Gly Tyr Cys Val Tyr Glu 
            340                 345                 350         


Glu Thr Gly Glu Phe Met Ser Ser Asn Ala Ser Glu Val Lys Arg Ile 
        355                 360                 365             


Pro Glu Gly Glu Lys Trp Glu Asp Gly Pro Cys Lys Val Cys Glu Cys 
    370                 375                 380                 


Arg Gly Ala Gln Val Thr Cys Tyr Glu Pro Ser Cys Pro Pro Cys Pro 
385                 390                 395                 400 


Val Gly Thr Leu Ala Leu Glu Val Lys Gly Gln Cys Cys Pro Asp Cys 
                405                 410                 415     


Thr Ser Val His Cys His Pro Asp Cys Leu Thr Cys Ser Gln Ser Pro 
            420                 425                 430         


Asp His Cys Asp Leu Cys Gln Asp Pro Thr Lys Leu Leu Gln Asn Gly 
        435                 440                 445             


Trp Cys Val His Ser Cys Gly Leu Gly Phe Tyr Gln Ala Gly Ser Leu 
    450                 455                 460                 


Cys Leu Ala Cys Gln Pro Gln Cys Ser Thr Cys Thr Ser Gly Leu Glu 
465                 470                 475                 480 


Cys Ser Ser Cys Gln Pro Pro Leu Leu Met Arg His Gly Gln Cys Val 
                485                 490                 495     


Pro Thr Cys Gly Asp Gly Phe Tyr Gln Asp Arg His Ser Cys Ala Val 
            500                 505                 510         


Cys His Glu Ser Cys Ala Gly Cys Trp Gly Pro Thr Glu Lys His Cys 
        515                 520                 525             


Leu Ala Cys Arg Asp Pro Leu His Val Leu Arg Asp Gly Gly Cys Glu 
    530                 535                 540                 


Ser Ser Cys Gly Lys Gly Phe Tyr Asn Arg Gln Gly Thr Cys Ser Ala 
545                 550                 555                 560 


Cys Asp Gln Ser Cys Asp Ser Cys Gly Pro Ser Ser Pro Arg Cys Leu 
                565                 570                 575     


Thr Cys Thr Glu Lys Thr Val Leu His Asp Gly Lys Cys Met Ser Glu 
            580                 585                 590         


Cys Pro Gly Gly Tyr Tyr Ala Asp Ala Thr Gly Arg Cys Lys Val Cys 
        595                 600                 605             


His Asn Ser Cys Ala Ser Cys Ser Gly Pro Thr Pro Ser His Cys Thr 
    610                 615                 620                 


Ala Cys Ser Pro Pro Lys Ala Leu Arg Gln Gly His Cys Leu Pro Arg 
625                 630                 635                 640 


Cys Gly Glu Gly Phe Tyr Ser Asp His Gly Val Cys Lys Ala Cys His 
                645                 650                 655     


Ser Ser Cys Leu Ala Cys Met Gly Pro Ala Pro Ser His Cys Thr Gly 
            660                 665                 670         


Cys Lys Lys Pro Glu Glu Gly Leu Gln Val Glu Gln Leu Ser Asp Val 
        675                 680                 685             


Gly Ile Pro Ser Gly Glu Cys Leu Ala Gln Cys Arg Ala His Phe Tyr 
    690                 695                 700                 


Leu Glu Ser Thr Gly Ile Cys Glu Ala Cys His Gln Ser Cys Phe Arg 
705                 710                 715                 720 


Cys Ala Gly Lys Ser Pro His Asn Cys Thr Asp Cys Gly Pro Ser His 
                725                 730                 735     


Val Leu Leu Asp Gly Gln Cys Leu Ser Gln Cys Pro Asp Gly Tyr Phe 
            740                 745                 750         


His Gln Glu Gly Ser Cys Thr Glu Cys His Pro Thr Cys Arg Gln Cys 
        755                 760                 765             


His Gly Pro Leu Glu Ser Asp Cys Ile Ser Cys Tyr Pro His Ile Ser 
    770                 775                 780                 


Leu Thr Asn Gly Asn Cys Arg Thr Ser Cys Arg Glu Glu Gln Phe Leu 
785                 790                 795                 800 


Asn Leu Val Gly Tyr Cys Ala Asp Cys His His Leu Cys Gln His Cys 
                805                 810                 815     


Ala Ala Asp Leu His Asn Thr Gly Ser Ile Cys Leu Arg Cys Gln Asn 
            820                 825                 830         


Ala His Tyr Leu Leu Leu Gly Asp His Cys Val Pro Asp Cys Pro Ser 
        835                 840                 845             


Gly Tyr Tyr Ala Glu Arg Gly Ala Cys Lys Lys Cys His Ser Ser Cys 
    850                 855                 860                 


Arg Thr Cys Gln Gly Arg Gly Pro Phe Ser Cys Ser Ser Cys Asp Thr 
865                 870                 875                 880 


Asn Leu Val Leu Ser His Thr Gly Thr Cys Ser Thr Thr Cys Phe Pro 
                885                 890                 895     


Gly His Tyr Leu Asp Asp Asn His Val Cys Gln Pro Cys Asn Thr His 
            900                 905                 910         


Cys Gly Ser Cys Asp Ser Gln Ala Ser Cys Thr Ser Cys Arg Asp Pro 
        915                 920                 925             


Asn Lys Val Leu Leu Phe Gly Glu Cys Gln Tyr Glu Ser Cys Ala Pro 
    930                 935                 940                 


Gln Tyr Tyr Leu Asp Phe Ser Thr Asn Thr Cys Lys Glu Cys Asp Trp 
945                 950                 955                 960 


Ser Cys Ser Ala Cys Ser Gly Pro Leu Lys Thr Asp Cys Leu Gln Cys 
                965                 970                 975     


Met Asp Gly Tyr Val Leu Gln Asp Gly Ala Cys Val Glu Gln Cys Leu 
            980                 985                 990         


Ser Ser Phe Tyr Gln Asp Ser Gly  Leu Cys Lys Asn Cys  Asp Ser Tyr 
        995                 1000                 1005             


Cys Leu  Gln Cys Gln Gly Pro  His Glu Cys Thr Arg  Cys Lys Gly 
    1010                 1015                 1020             


Pro Phe  Leu Leu Leu Glu Ala  Gln Cys Val Gln Glu  Cys Gly Lys 
    1025                 1030                 1035             


Gly Tyr  Phe Ala Asp His Ala  Lys His Lys Cys Thr  Ala Cys Pro 
    1040                 1045                 1050             


Gln Gly  Cys Leu Gln Cys Ser  His Arg Asp Arg Cys  His Leu Cys 
    1055                 1060                 1065             


Asp His  Gly Phe Phe Leu Lys  Ser Gly Leu Cys Val  Tyr Asn Cys 
    1070                 1075                 1080             


Val Pro  Gly Phe Ser Val His  Thr Ser Asn Glu Thr  Cys Ser Gly 
    1085                 1090                 1095             


Lys Ile  His Thr Pro Ser Leu  His Val Asn Gly Ser  Leu Ile Leu 
    1100                 1105                 1110             


Pro Ile  Gly Ser Ile Lys Pro  Leu Asp Phe Ser Leu  Leu Asn Val 
    1115                 1120                 1125             


Gln Asp  Gln Glu Gly Arg Val  Glu Asp Leu Leu Phe  His Val Val 
    1130                 1135                 1140             


Ser Thr  Pro Thr Asn Gly Gln  Leu Val Leu Ser Arg  Asn Gly Lys 
    1145                 1150                 1155             


Glu Val  Gln Leu Asp Lys Ala  Gly Arg Phe Ser Trp  Lys Asp Val 
    1160                 1165                 1170             


Asn Glu  Lys Lys Val Arg Phe  Val His Ser Lys Glu  Lys Leu Arg 
    1175                 1180                 1185             


Lys Gly  Tyr Leu Phe Leu Lys  Ile Ser Asp Gln Gln  Phe Phe Ser 
    1190                 1195                 1200             


Glu Pro  Gln Leu Ile Asn Ile  Gln Ala Phe Ser Thr  Gln Ala Pro 
    1205                 1210                 1215             


Tyr Val  Leu Arg Asn Glu Val  Leu His Ile Ser Arg  Gly Glu Arg 
    1220                 1225                 1230             


Ala Thr  Ile Thr Thr Gln Met  Leu Asp Ile Arg Asp  Asp Asp Asn 
    1235                 1240                 1245             


Pro Gln  Asp Val Val Ile Glu  Ile Ile Asp Pro Pro  Leu His Gly 
    1250                 1255                 1260             


Gln Leu  Leu Gln Thr Leu Gln  Ser Pro Ala Thr Pro  Ile Tyr Gln 
    1265                 1270                 1275             


Phe Gln  Leu Asp Glu Leu Ser  Arg Gly Leu Leu His  Tyr Ala His 
    1280                 1285                 1290             


Asp Gly  Ser Asp Ser Thr Ser  Asp Val Ala Val Leu  Gln Ala Asn 
    1295                 1300                 1305             


Asp Gly  His Ser Phe His Asn  Ile Leu Phe Gln Val  Lys Thr Val 
    1310                 1315                 1320             


Pro Gln  Asn Asp Arg Gly Leu  Gln Leu Val Ala Asn  Ser Met Val 
    1325                 1330                 1335             


Trp Val  Pro Glu Gly Gly Met  Leu Gln Ile Thr Asn  Arg Ile Leu 
    1340                 1345                 1350             


Gln Ala  Glu Ala Pro Gly Ala  Ser Ala Glu Glu Ile  Ile Tyr Lys 
    1355                 1360                 1365             


Ile Thr  Gln Asp Tyr Pro Gln  Phe Gly Glu Val Val  Leu Leu Val 
    1370                 1375                 1380             


Asn Met  Pro Ala Asp Ser Pro  Ala Asp Glu Gly Gln  His Leu Pro 
    1385                 1390                 1395             


Asp Gly  Arg Thr Ala Thr Pro  Thr Ser Thr Phe Thr  Gln Gln Asp 
    1400                 1405                 1410             


Ile Asn  Glu Gly Ile Val Trp  Tyr Arg His Ser Gly  Ala Pro Ala 
    1415                 1420                 1425             


Gln Ser  Asp Ser Phe Arg Phe  Glu Val Ser Ser Ala  Ser Asn Ala 
    1430                 1435                 1440             


Gln Thr  Arg Leu Glu Ser His  Met Phe Asn Ile Ala  Ile Leu Pro 
    1445                 1450                 1455             


Gln Thr  Pro Glu Ala Pro Lys  Val Ser Leu Glu Ala  Ser Leu His 
    1460                 1465                 1470             


Met Thr  Ala Arg Glu Asp Gly  Leu Thr Val Ile Gln  Pro His Ser 
    1475                 1480                 1485             


Leu Ser  Phe Ile Asn Ser Glu  Lys Pro Ser Gly Lys  Ile Val Tyr 
    1490                 1495                 1500             


Asn Ile  Thr Leu Pro Leu His  Pro Asn Gln Gly Ile  Ile Glu His 
    1505                 1510                 1515             


Arg Asp  His Pro His Ser Pro  Ile Arg Tyr Phe Thr  Gln Glu Asp 
    1520                 1525                 1530             


Ile Asn  Gln Gly Lys Val Met  Tyr Arg Pro Pro Pro  Ala Ala Pro 
    1535                 1540                 1545             


His Leu  Gln Glu Leu Met Ala  Phe Ser Phe Ala Gly  Leu Pro Glu 
    1550                 1555                 1560             


Ser Val  Lys Phe His Phe Thr  Val Ser Asp Gly Glu  His Thr Ser 
    1565                 1570                 1575             


Pro Glu  Met Val Leu Thr Ile  His Leu Leu Pro Ser  Asp Gln Gln 
    1580                 1585                 1590             


Leu Pro  Val Phe Gln Val Thr  Ala Pro Arg Leu Ala  Val Ser Pro 
    1595                 1600                 1605             


Gly Gly  Ser Thr Ser Val Gly  Leu Gln Val Val Val  Arg Asp Ala 
    1610                 1615                 1620             


Glu Thr  Ala Pro Lys Glu Leu  Phe Phe Glu Leu Arg  Arg Pro Pro 
    1625                 1630                 1635             


Gln His  Gly Val Leu Leu Lys  His Thr Ala Glu Phe  Arg Arg Pro 
    1640                 1645                 1650             


Met Ala  Thr Gly Asp Thr Phe  Thr Tyr Glu Asp Val  Glu Lys Asn 
    1655                 1660                 1665             


Ala Leu  Gln Tyr Ile His Asp  Gly Ser Ser Thr Arg  Glu Asp Ser 
    1670                 1675                 1680             


Met Glu  Ile Ser Val Thr Asp  Gly Leu Thr Val Thr  Met Leu Glu 
    1685                 1690                 1695             


Val Arg  Val Glu Val Ser Leu  Ser Glu Asp Arg Gly  Pro Arg Leu 
    1700                 1705                 1710             


Ala Ala  Gly Ser Ser Leu Ser  Ile Thr Val Ala Ser  Lys Ser Thr 
    1715                 1720                 1725             


Ala Ile  Ile Thr Arg Ser His  Leu Ala Tyr Val Asp  Asp Ser Ser 
    1730                 1735                 1740             


Pro Asp  Pro Glu Ile Trp Ile  Gln Leu Asn Tyr Leu  Pro Ser Tyr 
    1745                 1750                 1755             


Gly Thr  Leu Leu Arg Ile Ser  Gly Ser Glu Val Glu  Glu Leu Ser 
    1760                 1765                 1770             


Glu Val  Ser Asn Phe Thr Met  Glu Asp Ile Asn Asn  Lys Lys Ile 
    1775                 1780                 1785             


Arg Tyr  Ser Ala Val Phe Glu  Thr Asp Gly His Leu  Val Thr Asp 
    1790                 1795                 1800             


Ser Phe  Tyr Phe Ser Val Ser  Asp Met Asp His Asn  His Leu Asp 
    1805                 1810                 1815             


Asn Gln  Ile Phe Thr Ile Met  Ile Thr Pro Ala Glu  Asn Pro Pro 
    1820                 1825                 1830             


Pro Val  Ile Ala Phe Ala Asp  Leu Ile Thr Val Asp  Glu Gly Gly 
    1835                 1840                 1845             


Arg Ala  Pro Leu Ser Phe His  His Phe Phe Ala Thr  Asp Asp Asp 
    1850                 1855                 1860             


Asp Asn  Leu Gln Arg Asp Ala  Ile Ile Lys Leu Ser  Ala Leu Pro 
    1865                 1870                 1875             


Lys Tyr  Gly Cys Ile Glu Asn  Thr Gly Thr Gly Asp  Arg Phe Gly 
    1880                 1885                 1890             


Pro Glu  Thr Ala Ser Asp Leu  Glu Ala Ser Phe Pro  Ile Gln Asp 
    1895                 1900                 1905             


Val Leu  Glu Asn Tyr Ile Tyr  Tyr Phe Gln Ser Val  His Glu Ser 
    1910                 1915                 1920             


Ile Glu  Pro Thr His Asp Ile  Phe Ser Phe Tyr Val  Ser Asp Gly 
    1925                 1930                 1935             


Thr Ser  Arg Ser Glu Ile His  Ser Ile Asn Ile Thr  Ile Glu Arg 
    1940                 1945                 1950             


Lys Asn  Asp Glu Pro Pro Arg  Met Thr Leu Gln Pro  Leu Arg Val 
    1955                 1960                 1965             


Gln Leu  Ser Ser Gly Val Val  Ile Ser Asn Ser Ser  Leu Ser Leu 
    1970                 1975                 1980             


Gln Asp  Leu Asp Thr Pro Asp  Asn Glu Leu Ile Phe  Val Leu Thr 
    1985                 1990                 1995             


Lys Lys  Pro Asp His Gly His  Val Leu Trp Arg Gln  Thr Ala Ser 
    2000                 2005                 2010             


Glu Pro  Leu Glu Asn Gly Arg  Val Leu Val Gln Gly  Ser Thr Phe 
    2015                 2020                 2025             


Thr Tyr  Gln Asp Ile Leu Ala  Gly Leu Val Gly Tyr  Val Pro Ser 
    2030                 2035                 2040             


Val Pro  Gly Met Val Val Asp  Glu Phe Gln Phe Ser  Leu Thr Asp 
    2045                 2050                 2055             


Gly Leu  His Val Asp Thr Gly  Arg Met Lys Ile Tyr  Thr Glu Leu 
    2060                 2065                 2070             


Pro Ala  Ser Asp Thr Pro His  Leu Ala Ile Asn Gln  Gly Leu Gln 
    2075                 2080                 2085             


Leu Ser  Ala Gly Ser Val Ala  Arg Ile Thr Glu Gln  His Leu Lys 
    2090                 2095                 2100             


Val Thr  Asp Ile Asp Ser Asp  Asp His Gln Val Met  Tyr Ile Met 
    2105                 2110                 2115             


Lys Glu  Asp Pro Gly Ala Gly  Arg Leu Gln Met Met  Lys His Gly 
    2120                 2125                 2130             


Asn Leu  Glu Gln Ile Ser Ile  Lys Gly Pro Ile Arg  Ser Phe Thr 
    2135                 2140                 2145             


Gln Ala  Asp Ile Ser Gln Gly  His Val Glu Tyr Ser  His Gly Thr 
    2150                 2155                 2160             


Gly Glu  Pro Gly Gly Ser Phe  Ala Phe Lys Phe Asp  Val Val Asp 
    2165                 2170                 2175             


Gly Glu  Gly Asn Arg Leu Ile  Asp Lys Ser Phe Ser  Ile Ser Ile 
    2180                 2185                 2190             


Leu Glu  Asp Lys Ser Pro Pro  Val Ile Thr Thr Asn  Lys Gly Leu 
    2195                 2200                 2205             


Val Leu  Asp Glu Asn Ser Val  Lys Lys Ile Thr Thr  Leu Gln Leu 
    2210                 2215                 2220             


Ser Ala  Thr Asp Gln Asp Ser  Gly Pro Thr Glu Leu  Ile Tyr Arg 
    2225                 2230                 2235             


Ile Thr  Arg Gln Pro Gln Leu  Gly His Leu Glu His  Ala Ala Ser 
    2240                 2245                 2250             


Pro Gly  Ile Gln Ile Ser Ser  Phe Thr Gln Ala Asp  Leu Thr Ser 
    2255                 2260                 2265             


Arg Asn  Val Gln Tyr Val His  Ser Ser Glu Ala Glu  Lys His Ser 
    2270                 2275                 2280             


Asp Ala  Phe Ser Phe Thr Leu  Ser Asp Gly Val Ser  Glu Val Thr 
    2285                 2290                 2295             


Gln Thr  Phe His Ile Thr Leu  His Pro Val Asp Asp  Ser Leu Pro 
    2300                 2305                 2310             


Val Val  Gln Asn Leu Gly Met  Arg Val Gln Glu Gly  Met Arg Lys 
    2315                 2320                 2325             


Thr Ile  Thr Glu Phe Glu Leu  Lys Ala Val Asp Ala  Asp Thr Glu 
    2330                 2335                 2340             


Ala Glu  Ser Val Thr Phe Thr  Ile Val Gln Pro Pro  Arg His Gly 
    2345                 2350                 2355             


Thr Ile  Glu Arg Thr Ser Asn  Gly Gln His Phe His  Leu Thr Ser 
    2360                 2365                 2370             


Thr Phe  Thr Met Lys Asp Ile  Tyr Gln Asn Arg Val  Ser Tyr Ser 
    2375                 2380                 2385             


His Asp  Gly Ser Asn Ser Leu  Lys Asp Arg Phe Thr  Phe Thr Val 
    2390                 2395                 2400             


Ser Asp  Gly Thr Asn Pro Phe  Phe Ile Ile Glu Glu  Gly Gly Lys 
    2405                 2410                 2415             


Glu Ile  Met Thr Ala Ala Pro  Gln Pro Phe Arg Val  Asp Ile Leu 
    2420                 2425                 2430             


Pro Val  Asp Asp Gly Thr Pro  Arg Ile Val Thr Asn  Leu Gly Leu 
    2435                 2440                 2445             


Gln Trp  Leu Glu Tyr Met Asp  Gly Lys Ala Thr Asn  Leu Ile Thr 
    2450                 2455                 2460             


Lys Lys  Glu Leu Leu Thr Met  Asp Pro Asp Thr Glu  Asp Ala Gln 
    2465                 2470                 2475             


Leu Val  Tyr Glu Ile Thr Thr  Gly Pro Lys His Gly  Phe Val Glu 
    2480                 2485                 2490             


Asn Lys  Leu Gln Pro Gly Arg  Ala Ala Ala Thr Phe  Thr Gln Glu 
    2495                 2500                 2505             


Asp Val  Asn Leu Gly Leu Ile  Arg Tyr Val Leu His  Lys Glu Lys 
    2510                 2515                 2520             


Ile Arg  Glu Met Met Asp Ser  Phe Gln Phe Leu Val  Lys Asp Ser 
    2525                 2530                 2535             


Lys Pro  Asn Val Val Ser Asp  Asn Val Phe His Ile  Gln Trp Ser 
    2540                 2545                 2550             


Leu Ile  Ser Phe Lys Tyr Thr  Ser Tyr Asn Val Ser  Glu Lys Ala 
    2555                 2560                 2565             


Gly Ser  Val Ser Val Thr Val  Gln Arg Thr Gly Asn  Leu Asn Gln 
    2570                 2575                 2580             


Tyr Ala  Ile Val Leu Cys Arg  Thr Glu Gln Gly Thr  Ala Ser Ser 
    2585                 2590                 2595             


Ser Ser  Arg Val Ser Ser Gln  Pro Gly Gln Gln Asp  Tyr Val Glu 
    2600                 2605                 2610             


Tyr Ala  Gly Gln Val Gln Phe  Asp Glu Arg Glu Asp  Thr Lys Ser 
    2615                 2620                 2625             


Cys Thr  Ile Val Ile Asn Asp  Asp Asp Val Phe Glu  Asn Val Glu 
    2630                 2635                 2640             


Ser Phe  Thr Val Glu Leu Ser  Met Pro Ala Tyr Ala  Leu Leu Gly 
    2645                 2650                 2655             


Glu Phe  Thr Gln Ala Lys Val  Ile Ile Asn Asp Thr  Glu Asp Glu 
    2660                 2665                 2670             


Pro Thr  Leu Glu Phe Asp Lys  Lys Ile Tyr Trp Val  Asn Glu Ser 
    2675                 2680                 2685             


Ala Gly  Phe Leu Phe Ala Pro  Ile Glu Arg Lys Gly  Asp Ala Ser 
    2690                 2695                 2700             


Ser Ile  Val Ser Ala Ile Cys  Tyr Thr Val Pro Lys  Ser Ala Met 
    2705                 2710                 2715             


Gly Ser  Ser Leu Tyr Ala Leu  Glu Ser Gly Ser Asp  Phe Lys Ser 
    2720                 2725                 2730             


Arg Gly  Met Ser Ala Ala Ser  Arg Val Ile Phe Gly  Pro Gly Val 
    2735                 2740                 2745             


Thr Met  Ser Thr Cys Asp Val  Met Leu Ile Asp Asp  Ser Glu Tyr 
    2750                 2755                 2760             


Glu Glu  Glu Glu Glu Phe Glu  Ile Ala Leu Ala Asp  Ala Ser Asp 
    2765                 2770                 2775             


Asn Ala  Arg Ile Gly Arg Val  Ala Thr Ala Lys Val  Leu Ile Ser 
    2780                 2785                 2790             


Gly Pro  Asn Asp Ala Ser Thr  Val Ser Leu Gly Asn  Thr Ala Phe 
    2795                 2800                 2805             


Thr Val  Ser Glu Asp Ala Gly  Thr Val Lys Ile Pro  Val Ile Arg 
    2810                 2815                 2820             


His Gly  Thr Asp Leu Ser Thr  Phe Ala Ser Val Trp  Cys Ala Thr 
    2825                 2830                 2835             


Arg Pro  Ser Asp Pro Ala Ser  Ala Thr Pro Gly Val  Asp Tyr Val 
    2840                 2845                 2850             


Pro Ser  Ser Arg Lys Val Glu  Phe Gly Pro Gly Val  Ile Glu Gln 
    2855                 2860                 2865             


Tyr Cys  Thr Leu Thr Ile Leu  Asp Asp Thr Gln Tyr  Pro Val Ile 
    2870                 2875                 2880             


Glu Gly  Leu Glu Thr Phe Val  Val Phe Leu Ser Ser  Ala Gln Gly 
    2885                 2890                 2895             


Ala Glu  Leu Thr Lys Pro Phe  Gln Ala Val Ile Ala  Ile Asn Asp 
    2900                 2905                 2910             


Thr Phe  Gln Asp Val Pro Ser  Met Gln Phe Ala Lys  Asp Leu Leu 
    2915                 2920                 2925             


Leu Val  Lys Glu Lys Glu Gly  Val Leu His Val Pro  Ile Thr Arg 
    2930                 2935                 2940             


Ser Gly  Asp Leu Ser Tyr Glu  Ser Ser Val Arg Cys  Tyr Thr Gln 
    2945                 2950                 2955             


Ser His  Ser Ala Gln Val Met  Glu Asp Phe Glu Glu  Arg Gln Asn 
    2960                 2965                 2970             


Ala Asp  Ser Ser Arg Ile Thr  Phe Leu Lys Gly Asp  Lys Val Lys 
    2975                 2980                 2985             


Asn Cys  Thr Val Tyr Ile His  Asp Asp Ser Met Phe  Glu Pro Glu 
    2990                 2995                 3000             


Glu Gln  Phe Arg Val Tyr Leu  Gly Leu Pro Leu Gly  Asn His Trp 
    3005                 3010                 3015             


Ser Gly  Ala Arg Ile Gly Lys  Asn Asn Met Ala Thr  Ile Thr Ile 
    3020                 3025                 3030             


Ser Asn  Asp Glu Asp Ala Pro  Thr Ile Glu Phe Glu  Glu Ala Ala 
    3035                 3040                 3045             


Tyr Gln  Val Arg Glu Pro Ala  Gly Pro Asp Ala Ile  Ala Ile Leu 
    3050                 3055                 3060             


Asn Ile  Lys Val Ile Arg Arg  Gly Asp Gln Asn Arg  Thr Ser Lys 
    3065                 3070                 3075             


Val Arg  Cys Ser Thr Arg Asp  Gly Ser Ala Gln Ser  Gly Val Asp 
    3080                 3085                 3090             


Tyr Tyr  Pro Lys Ser Arg Val  Leu Lys Phe Ser Pro  Gly Val Asp 
    3095                 3100                 3105             


His Ile  Phe Phe Lys Val Glu  Ile Leu Ser Asn Glu  Asp Arg Glu 
    3110                 3115                 3120             


Trp His  Glu Ser Phe Ser Leu  Val Leu Gly Pro Asp  Asp Pro Val 
    3125                 3130                 3135             


Glu Ala  Val Leu Gly Asp Val  Thr Thr Ala Thr Val  Thr Ile Leu 
    3140                 3145                 3150             


Asp Gln  Glu Ala Ala Gly Ser  Leu Ile Leu Pro Ala  Pro Pro Ile 
    3155                 3160                 3165             


Val Val  Thr Leu Ala Asp Tyr  Asp His Val Glu Glu  Val Thr Lys 
    3170                 3175                 3180             


Glu Gly  Val Lys Lys Ser Pro  Ser Pro Gly Tyr Pro  Leu Val Cys 
    3185                 3190                 3195             


Val Thr  Pro Cys Asp Pro His  Phe Pro Arg Tyr Ala  Val Met Lys 
    3200                 3205                 3210             


Glu Arg  Cys Ser Glu Ala Gly  Ile Asn Gln Thr Ser  Val Gln Phe 
    3215                 3220                 3225             


Ser Trp  Glu Val Ala Ala Pro  Thr Asp Gly Asn Gly  Ala Arg Ser 
    3230                 3235                 3240             


Pro Phe  Glu Thr Ile Thr Asp  Asn Thr Pro Phe Thr  Ser Val Asn 
    3245                 3250                 3255             


His Met  Val Leu Asp Ser Ile  Tyr Phe Ser Arg Arg  Phe His Val 
    3260                 3265                 3270             


Arg Cys  Val Ala Lys Ala Val  Asp Lys Val Gly His  Val Gly Thr 
    3275                 3280                 3285             


Pro Leu  Arg Ser Asn Ile Val  Thr Ile Gly Thr Asp  Ser Ala Ile 
    3290                 3295                 3300             


Cys His  Thr Pro Val Val Ala  Gly Thr Ser Arg Gly  Phe Gln Ala 
    3305                 3310                 3315             


Gln Ser  Phe Ile Ala Thr Leu  Lys Tyr Leu Asp Val  Lys His Lys 
    3320                 3325                 3330             


Glu His  Pro Asn Arg Ile His  Ile Ser Val Gln Ile  Pro His Gln 
    3335                 3340                 3345             


Asp Gly  Met Leu Pro Leu Ile  Ser Thr Met Pro Leu  His Asn Leu 
    3350                 3355                 3360             


His Phe  Leu Leu Ser Glu Ser  Ile Tyr Arg His Gln  His Val Cys 
    3365                 3370                 3375             


Ser Asn  Leu Val Thr Thr Tyr  Asp Leu Arg Gly Ile  Ser Glu Ala 
    3380                 3385                 3390             


Gly Phe  Leu Asp Asp Val Val  Tyr Asp Ser Thr Ala  Leu Gly Pro 
    3395                 3400                 3405             


Gly Tyr  Asp Arg Pro Phe Gln  Phe Asp Pro Ser Val  Arg Glu Pro 
    3410                 3415                 3420             


Lys Thr  Ile Gln Leu Tyr Lys  His Leu Asn Leu Lys  Ser Cys Val 
    3425                 3430                 3435             


Trp Thr  Phe Asp Ala Tyr Tyr  Asp Met Thr Glu Leu  Ile Asp Val 
    3440                 3445                 3450             


Cys Gly  Gly Ser Val Thr Ala  Asp Phe Gln Val Arg  Asp Ser Ala 
    3455                 3460                 3465             


Gln Ser  Phe Leu Thr Val His  Val Pro Leu Tyr Val  Ser Tyr Ile 
    3470                 3475                 3480             


Tyr Val  Thr Ala Pro Arg Gly  Trp Ala Ser Leu Glu  His His Thr 
    3485                 3490                 3495             


Glu Met  Glu Phe Ser Phe Phe  Tyr Asp Thr Val Leu  Trp Arg Thr 
    3500                 3505                 3510             


Gly Ile  Gln Thr Asp Ser Val  Leu Ser Ala Arg Leu  Gln Ile Ile 
    3515                 3520                 3525             


Arg Ile  Tyr Ile Arg Glu Asp  Gly Arg Leu Val Ile  Glu Phe Lys 
    3530                 3535                 3540             


Thr His  Ala Lys Phe Arg Gly  Gln Phe Val Met Glu  His His Thr 
    3545                 3550                 3555             


Leu Pro  Glu Val Lys Ser Phe  Val Leu Thr Pro Asp  His Leu Gly 
    3560                 3565                 3570             


Gly Ile  Glu Phe Asp Leu Gln  Leu Leu Trp Ser Ala  Gln Thr Phe 
    3575                 3580                 3585             


Asp Ser  Pro His Gln Leu Trp  Arg Ala Thr Ser Ser  Tyr Asn Arg 
    3590                 3595                 3600             


Lys Asp  Tyr Ser Gly Glu Tyr  Thr Ile Tyr Leu Ile  Pro Cys Thr 
    3605                 3610                 3615             


Val Gln  Pro Thr Gln Pro Trp  Val Asp Pro Gly Glu  Lys Pro Leu 
    3620                 3625                 3630             


Ala Cys  Thr Ala His Ala Pro  Glu Arg Phe Leu Ile  Pro Ile Ala 
    3635                 3640                 3645             


Phe Gln  Gln Thr Asn Arg Pro  Val Pro Val Val Tyr  Ser Leu Asn 
    3650                 3655                 3660             


Thr Glu  Phe Gln Leu Cys Asn  Asn Glu Lys Val Phe  Leu Met Asp 
    3665                 3670                 3675             


Pro Asn  Thr Ser Asp Met Ser  Leu Ala Glu Met Asp  Tyr Lys Gly 
    3680                 3685                 3690             


Ala Phe  Ser Lys Gly Gln Ile  Leu Tyr Gly Arg Val  Leu Trp Asn 
    3695                 3700                 3705             


Pro Glu  Gln Asn Leu Asn Ser  Ala Tyr Lys Leu Gln  Leu Glu Lys 
    3710                 3715                 3720             


Val Tyr  Leu Cys Thr Gly Lys  Asp Gly Tyr Val Pro  Phe Phe Asp 
    3725                 3730                 3735             


Pro Thr  Gly Thr Ile Tyr Asn  Glu Gly Pro Gln Tyr  Gly Cys Ile 
    3740                 3745                 3750             


Gln Pro  Asn Lys His Leu Lys  His Arg Phe Leu Leu  Leu Asp Arg 
    3755                 3760                 3765             


Asn Gln  Pro Glu Val Thr Asp  Lys Tyr Phe His Asp  Val Pro Phe 
    3770                 3775                 3780             


Glu Ala  His Phe Ala Ser Glu  Leu Pro Asp Phe His  Val Val Ser 
    3785                 3790                 3795             


Asn Met  Pro Gly Val Asp Gly  Phe Thr Leu Lys Val  Asp Ala Leu 
    3800                 3805                 3810             


Tyr Lys  Val Glu Ala Gly His  Gln Trp Tyr Leu Gln  Val Ile Tyr 
    3815                 3820                 3825             


Ile Ile  Gly Pro Asp Thr Ile  Ser Gly Pro Arg Val  Gln Arg Ser 
    3830                 3835                 3840             


Leu Thr  Ala Pro Leu Arg Arg  Asn Arg Arg Asp Leu  Val Glu Pro 
    3845                 3850                 3855             


Asp Gly  Gln Leu Ile Leu Asp  Asp Ser Leu Ile Tyr  Asp Asn Glu 
    3860                 3865                 3870             


Gly Asp  Gln Val Lys Asn Gly  Thr Asn Met Lys Ser  Leu Asn Leu 
    3875                 3880                 3885             


Glu Met  Gln Glu Leu Ala Val  Ala Ala Ser Leu Ser  Gln Thr Gly 
    3890                 3895                 3900             


Ala Ser  Ile Gly Ser Ala Leu  Ala Ala Ile Met Leu  Leu Leu Leu 
    3905                 3910                 3915             


Val Phe  Leu Val Ala Cys Phe  Ile Asn Arg Lys Cys  Gln Lys Gln 
    3920                 3925                 3930             


Arg Lys  Lys Lys Pro Ala Glu  Asp Ile Leu Glu Glu  Tyr Pro Leu 
    3935                 3940                 3945             


Asn Thr  Lys Val Glu Val Pro  Lys Arg His Pro Asp  Arg Val Glu 
    3950                 3955                 3960             


Lys Asn  Val Asn Arg His Tyr  Cys Thr Val Arg Asn  Val Asn Ile 
    3965                 3970                 3975             


Leu Ser  Glu Pro Glu Ala Ala  Tyr Thr Phe Lys Gly  Ala Lys Val 
    3980                 3985                 3990             


Lys Arg  Leu Asn Leu Glu Val  Arg Val His Asn Asn  Leu Gln Asp 
    3995                 4000                 4005             


Gly Thr  Glu Val 
    4010         


<210>  3114
<211>  1586
<212>  PRT
<213>  homo sapiens

<400>  3114

Met Glu Thr Ser Ala Ser Ala Thr Ala Ser Glu Lys Gln Glu Ala Lys 
1               5                   10                  15      


Ser Gly Ile Leu Glu Ala Ala Gly Phe Pro Asp Pro Gly Lys Lys Ala 
            20                  25                  30          


Ser Pro Leu Val Val Ala Ala Ala Ala Ala Ala Ala Val Ala Ala Gln 
        35                  40                  45              


Gly Val Pro Gln His Leu Leu Pro Pro Phe His Ala Pro Leu Pro Ile 
    50                  55                  60                  


Asp Met Arg His Gln Glu Gly Arg Tyr His Tyr Glu Pro His Ser Val 
65                  70                  75                  80  


His Gly Val His Gly Pro Pro Ala Leu Ser Gly Ser Pro Val Ile Ser 
                85                  90                  95      


Asp Ile Ser Leu Ile Arg Leu Ser Pro His Pro Ala Gly Pro Gly Glu 
            100                 105                 110         


Ser Pro Phe Asn Ala Pro His Pro Tyr Val Asn Pro His Met Glu His 
        115                 120                 125             


Tyr Leu Arg Ser Val His Ser Ser Pro Thr Leu Ser Met Ile Ser Ala 
    130                 135                 140                 


Ala Arg Gly Leu Ser Pro Ala Asp Val Ala Gln Glu His Leu Lys Glu 
145                 150                 155                 160 


Arg Gly Leu Phe Gly Leu Pro Ala Pro Gly Thr Thr Pro Ser Asp Tyr 
                165                 170                 175     


Tyr His Gln Met Thr Leu Val Ala Gly His Pro Ala Pro Tyr Gly Asp 
            180                 185                 190         


Leu Leu Met Gln Ser Gly Gly Ala Ala Ser Ala Pro His Leu His Asp 
        195                 200                 205             


Tyr Leu Asn Pro Val Asp Val Ser Arg Phe Ser Ser Pro Arg Val Thr 
    210                 215                 220                 


Pro Arg Leu Ser Arg Lys Arg Ala Leu Ser Ile Ser Pro Leu Ser Asp 
225                 230                 235                 240 


Ala Ser Leu Asp Leu Gln Arg Met Ile Arg Thr Ser Pro Asn Ser Leu 
                245                 250                 255     


Val Ala Tyr Ile Asn Asn Ser Arg Ser Ser Ser Ala Ala Ser Gly Ser 
            260                 265                 270         


Tyr Gly His Leu Ser Ala Gly Ala Leu Ser Pro Ala Phe Thr Phe Pro 
        275                 280                 285             


His Pro Ile Asn Pro Val Ala Tyr Gln Gln Ile Leu Ser Gln Gln Arg 
    290                 295                 300                 


Gly Leu Gly Ser Ala Phe Gly His Thr Pro Pro Leu Ile Gln Pro Ser 
305                 310                 315                 320 


Pro Thr Phe Leu Ala Gln Gln Pro Met Ala Leu Thr Ser Ile Asn Ala 
                325                 330                 335     


Thr Pro Thr Gln Leu Ser Ser Ser Ser Asn Cys Leu Ser Asp Thr Asn 
            340                 345                 350         


Gln Asn Lys Gln Ser Ser Glu Ser Ala Val Ser Ser Thr Val Asn Pro 
        355                 360                 365             


Val Ala Ile His Lys Arg Ser Lys Val Lys Thr Glu Pro Glu Gly Leu 
    370                 375                 380                 


Arg Pro Ala Ser Pro Leu Ala Leu Thr Gln Gly Gln Val Ser Gly His 
385                 390                 395                 400 


Gly Ser Cys Gly Cys Ala Leu Pro Leu Ser Gln Glu Gln Leu Ala Asp 
                405                 410                 415     


Leu Lys Glu Asp Leu Asp Arg Asp Asp Cys Lys Gln Glu Ala Glu Val 
            420                 425                 430         


Val Ile Tyr Glu Thr Asn Cys His Trp Glu Asp Cys Thr Lys Glu Tyr 
        435                 440                 445             


Asp Thr Gln Glu Gln Leu Val His His Ile Asn Asn Glu His Ile His 
    450                 455                 460                 


Gly Glu Lys Lys Glu Phe Val Cys Arg Trp Gln Ala Cys Thr Arg Glu 
465                 470                 475                 480 


Gln Lys Pro Phe Lys Ala Gln Tyr Met Leu Val Val His Met Arg Arg 
                485                 490                 495     


His Thr Gly Glu Lys Pro His Lys Cys Thr Phe Glu Gly Cys Ser Lys 
            500                 505                 510         


Ala Tyr Ser Arg Leu Glu Asn Leu Lys Thr His Leu Arg Ser His Thr 
        515                 520                 525             


Gly Glu Lys Pro Tyr Val Cys Glu His Glu Gly Cys Asn Lys Ala Phe 
    530                 535                 540                 


Ser Asn Ala Ser Asp Arg Ala Lys His Gln Asn Arg Thr His Ser Asn 
545                 550                 555                 560 


Glu Lys Pro Tyr Ile Cys Lys Ile Pro Gly Cys Thr Lys Arg Tyr Thr 
                565                 570                 575     


Asp Pro Ser Ser Leu Arg Lys His Val Lys Thr Val His Gly Pro Asp 
            580                 585                 590         


Ala His Val Thr Lys Lys Gln Arg Asn Asp Val His Leu Arg Thr Pro 
        595                 600                 605             


Leu Leu Lys Glu Asn Gly Asp Ser Glu Ala Gly Thr Glu Pro Gly Gly 
    610                 615                 620                 


Pro Glu Ser Thr Glu Ala Ser Ser Thr Ser Gln Ala Val Glu Asp Cys 
625                 630                 635                 640 


Leu His Val Arg Ala Ile Lys Thr Glu Ser Ser Gly Leu Cys Gln Ser 
                645                 650                 655     


Ser Pro Gly Ala Gln Ser Ser Cys Ser Ser Glu Pro Ser Pro Leu Gly 
            660                 665                 670         


Ser Ala Pro Asn Asn Asp Ser Gly Val Glu Met Pro Gly Thr Gly Pro 
        675                 680                 685             


Gly Ser Leu Gly Asp Leu Thr Ala Leu Asp Asp Thr Pro Pro Gly Ala 
    690                 695                 700                 


Asp Thr Ser Ala Leu Ala Ala Pro Ser Ala Gly Gly Leu Gln Leu Arg 
705                 710                 715                 720 


Lys His Met Thr Thr Met His Arg Phe Glu Gln Leu Lys Lys Glu Lys 
                725                 730                 735     


Leu Lys Ser Leu Lys Asp Ser Cys Ser Trp Ala Gly Pro Thr Pro His 
            740                 745                 750         


Thr Arg Asn Thr Lys Leu Pro Pro Leu Pro Gly Ser Gly Ser Ile Leu 
        755                 760                 765             


Glu Asn Phe Ser Gly Ser Gly Gly Gly Gly Pro Ala Gly Leu Leu Pro 
    770                 775                 780                 


Asn Pro Arg Leu Ser Glu Leu Ser Ala Ser Glu Val Thr Met Leu Ser 
785                 790                 795                 800 


Gln Leu Gln Glu Arg Arg Asp Ser Ser Thr Ser Thr Val Ser Ser Ala 
                805                 810                 815     


Tyr Thr Val Ser Arg Arg Ser Ser Gly Ile Ser Pro Tyr Phe Ser Ser 
            820                 825                 830         


Arg Arg Ser Ser Glu Ala Ser Pro Leu Gly Ala Gly Arg Pro His Asn 
        835                 840                 845             


Ala Ser Ser Ala Asp Ser Tyr Asp Pro Ile Ser Thr Asp Ala Ser Arg 
    850                 855                 860                 


Arg Ser Ser Glu Ala Ser Gln Cys Ser Gly Gly Ser Gly Leu Leu Asn 
865                 870                 875                 880 


Leu Thr Pro Ala Gln Gln Tyr Ser Leu Arg Ala Lys Tyr Ala Ala Ala 
                885                 890                 895     


Thr Gly Gly Pro Pro Pro Thr Pro Leu Pro Gly Leu Glu Arg Met Ser 
            900                 905                 910         


Leu Arg Thr Arg Leu Ala Leu Leu Asp Ala Pro Glu Arg Thr Leu Pro 
        915                 920                 925             


Ala Gly Cys Pro Arg Pro Leu Gly Pro Arg Arg Gly Ser Asp Gly Pro 
    930                 935                 940                 


Thr Tyr Gly His Gly His Ala Gly Ala Ala Pro Ala Phe Pro His Glu 
945                 950                 955                 960 


Ala Pro Gly Gly Gly Ala Arg Arg Ala Ser Asp Pro Val Arg Arg Pro 
                965                 970                 975     


Asp Ala Leu Ser Leu Pro Arg Val Gln Arg Phe His Ser Thr His Asn 
            980                 985                 990         


Val Asn Pro Gly Pro Leu Pro Pro  Cys Ala Asp Arg Arg  Gly Leu Arg 
        995                 1000                 1005             


Leu Gln  Ser His Pro Ser Thr  Asp Gly Gly Leu Ala  Arg Gly Ala 
    1010                 1015                 1020             


Tyr Ser  Pro Arg Pro Pro Ser  Ile Ser Glu Asn Val  Ala Met Glu 
    1025                 1030                 1035             


Ala Val  Ala Ala Gly Val Asp  Gly Ala Gly Pro Glu  Ala Asp Leu 
    1040                 1045                 1050             


Gly Leu  Pro Glu Asp Asp Leu  Val Leu Pro Asp Asp  Val Val Gln 
    1055                 1060                 1065             


Tyr Ile  Lys Ala His Ala Ser  Gly Ala Leu Asp Glu  Gly Thr Gly 
    1070                 1075                 1080             


Gln Val  Tyr Pro Thr Glu Ser  Thr Gly Phe Ser Asp  Asn Pro Arg 
    1085                 1090                 1095             


Leu Pro  Ser Pro Gly Leu His  Gly Gln Arg Arg Met  Val Ala Ala 
    1100                 1105                 1110             


Asp Ser  Asn Val Gly Pro Ser  Ala Pro Met Leu Gly  Gly Cys Gln 
    1115                 1120                 1125             


Leu Gly  Phe Gly Ala Pro Ser  Ser Leu Asn Lys Asn  Asn Met Pro 
    1130                 1135                 1140             


Val Gln  Trp Asn Glu Val Ser  Ser Gly Thr Val Asp  Ala Leu Ala 
    1145                 1150                 1155             


Ser Gln  Val Lys Pro Pro Pro  Phe Pro Gln Gly Asn  Leu Ala Val 
    1160                 1165                 1170             


Val Gln  Gln Lys Pro Ala Phe  Gly Gln Tyr Pro Gly  Tyr Ser Pro 
    1175                 1180                 1185             


Gln Gly  Leu Gln Ala Ser Pro  Gly Gly Leu Asp Ser  Thr Gln Pro 
    1190                 1195                 1200             


His Leu  Gln Pro Arg Ser Gly  Ala Pro Ser Gln Gly  Ile Pro Arg 
    1205                 1210                 1215             


Val Asn  Tyr Met Gln Gln Leu  Arg Gln Pro Val Ala  Gly Ser Gln 
    1220                 1225                 1230             


Cys Pro  Gly Met Thr Thr Thr  Met Ser Pro His Ala  Cys Tyr Gly 
    1235                 1240                 1245             


Gln Val  His Pro Gln Leu Ser  Pro Ser Thr Ile Ser  Gly Ala Leu 
    1250                 1255                 1260             


Asn Gln  Phe Pro Gln Ser Cys  Ser Asn Met Pro Ala  Lys Pro Gly 
    1265                 1270                 1275             


His Leu  Gly His Pro Gln Gln  Thr Glu Val Ala Pro  Asp Pro Thr 
    1280                 1285                 1290             


Thr Met  Gly Asn Arg His Arg  Glu Leu Gly Val Pro  Asp Ser Ala 
    1295                 1300                 1305             


Leu Ala  Gly Val Pro Pro Pro  His Pro Val Gln Ser  Tyr Pro Gln 
    1310                 1315                 1320             


Gln Ser  His His Leu Ala Ala  Ser Met Ser Gln Glu  Gly Tyr His 
    1325                 1330                 1335             


Gln Val  Pro Ser Leu Leu Pro  Ala Arg Gln Pro Gly  Phe Met Glu 
    1340                 1345                 1350             


Pro Gln  Thr Gly Pro Met Gly  Val Ala Thr Ala Gly  Phe Gly Leu 
    1355                 1360                 1365             


Val Gln  Pro Arg Pro Pro Leu  Glu Pro Ser Pro Thr  Gly Arg His 
    1370                 1375                 1380             


Arg Gly  Val Arg Ala Val Gln  Gln Gln Leu Ala Tyr  Ala Arg Ala 
    1385                 1390                 1395             


Thr Gly  His Ala Met Ala Ala  Met Pro Ser Ser Gln  Glu Thr Ala 
    1400                 1405                 1410             


Glu Ala  Val Pro Lys Gly Ala  Met Gly Asn Met Gly  Ser Val Pro 
    1415                 1420                 1425             


Pro Gln  Pro Pro Pro Gln Asp  Ala Gly Gly Ala Pro  Asp His Ser 
    1430                 1435                 1440             


Met Leu  Tyr Tyr Tyr Gly Gln  Ile His Met Tyr Glu  Gln Asp Gly 
    1445                 1450                 1455             


Gly Leu  Glu Asn Leu Gly Ser  Cys Gln Val Met Arg  Ser Gln Pro 
    1460                 1465                 1470             


Pro Gln  Pro Gln Ala Cys Gln  Asp Ser Ile Gln Pro  Gln Pro Leu 
    1475                 1480                 1485             


Pro Ser  Pro Gly Val Asn Gln  Val Ser Ser Thr Val  Asp Ser Gln 
    1490                 1495                 1500             


Leu Leu  Glu Ala Pro Gln Ile  Asp Phe Asp Ala Ile  Met Asp Asp 
    1505                 1510                 1515             


Gly Asp  His Ser Ser Leu Phe  Ser Gly Ala Leu Ser  Pro Ser Leu 
    1520                 1525                 1530             


Leu His  Ser Leu Ser Gln Asn  Ser Ser Arg Leu Thr  Thr Pro Arg 
    1535                 1540                 1545             


Asn Ser  Leu Thr Leu Pro Ser  Ile Pro Ala Gly Ile  Ser Asn Met 
    1550                 1555                 1560             


Ala Val  Gly Asp Met Ser Ser  Met Leu Thr Ser Leu  Ala Glu Glu 
    1565                 1570                 1575             


Ser Lys  Phe Leu Asn Met Met  Thr 
    1580                 1585     


<210>  3115
<211>  408
<212>  PRT
<213>  homo sapiens

<400>  3115

Met Ile Pro Gly Asn Arg Met Leu Met Val Val Leu Leu Cys Gln Val 
1               5                   10                  15      


Leu Leu Gly Gly Ala Ser His Ala Ser Leu Ile Pro Glu Thr Gly Lys 
            20                  25                  30          


Lys Lys Val Ala Glu Ile Gln Gly His Ala Gly Gly Arg Arg Ser Gly 
        35                  40                  45              


Gln Ser His Glu Leu Leu Arg Asp Phe Glu Ala Thr Leu Leu Gln Met 
    50                  55                  60                  


Phe Gly Leu Arg Arg Arg Pro Gln Pro Ser Lys Ser Ala Val Ile Pro 
65                  70                  75                  80  


Asp Tyr Met Arg Asp Leu Tyr Arg Leu Gln Ser Gly Glu Glu Glu Glu 
                85                  90                  95      


Glu Gln Ile His Ser Thr Gly Leu Glu Tyr Pro Glu Arg Pro Ala Ser 
            100                 105                 110         


Arg Ala Asn Thr Val Arg Ser Phe His His Glu Glu His Leu Glu Asn 
        115                 120                 125             


Ile Pro Gly Thr Ser Glu Asn Ser Ala Phe Arg Phe Leu Phe Asn Leu 
    130                 135                 140                 


Ser Ser Ile Pro Glu Asn Glu Val Ile Ser Ser Ala Glu Leu Arg Leu 
145                 150                 155                 160 


Phe Arg Glu Gln Val Asp Gln Gly Pro Asp Trp Glu Arg Gly Phe His 
                165                 170                 175     


Arg Ile Asn Ile Tyr Glu Val Met Lys Pro Pro Ala Glu Val Val Pro 
            180                 185                 190         


Gly His Leu Ile Thr Arg Leu Leu Asp Thr Arg Leu Val His His Asn 
        195                 200                 205             


Val Thr Arg Trp Glu Thr Phe Asp Val Ser Pro Ala Val Leu Arg Trp 
    210                 215                 220                 


Thr Arg Glu Lys Gln Pro Asn Tyr Gly Leu Ala Ile Glu Val Thr His 
225                 230                 235                 240 


Leu His Gln Thr Arg Thr His Gln Gly Gln His Val Arg Ile Ser Arg 
                245                 250                 255     


Ser Leu Pro Gln Gly Ser Gly Asn Trp Ala Gln Leu Arg Pro Leu Leu 
            260                 265                 270         


Val Thr Phe Gly His Asp Gly Arg Gly His Ala Leu Thr Arg Arg Arg 
        275                 280                 285             


Arg Ala Lys Arg Ser Pro Lys His His Ser Gln Arg Ala Arg Lys Lys 
    290                 295                 300                 


Asn Lys Asn Cys Arg Arg His Ser Leu Tyr Val Asp Phe Ser Asp Val 
305                 310                 315                 320 


Gly Trp Asn Asp Trp Ile Val Ala Pro Pro Gly Tyr Gln Ala Phe Tyr 
                325                 330                 335     


Cys His Gly Asp Cys Pro Phe Pro Leu Ala Asp His Leu Asn Ser Thr 
            340                 345                 350         


Asn His Ala Ile Val Gln Thr Leu Val Asn Ser Val Asn Ser Ser Ile 
        355                 360                 365             


Pro Lys Ala Cys Cys Val Pro Thr Glu Leu Ser Ala Ile Ser Met Leu 
    370                 375                 380                 


Tyr Leu Asp Glu Tyr Asp Lys Val Val Leu Lys Asn Tyr Gln Glu Met 
385                 390                 395                 400 


Val Val Glu Gly Cys Gly Cys Arg 
                405             


<210>  3116
<211>  204
<212>  PRT
<213>  homo sapiens

<400>  3116

Met Asp Glu Thr Val Ala Glu Phe Ile Lys Arg Thr Ile Leu Lys Ile 
1               5                   10                  15      


Pro Met Asn Glu Leu Thr Thr Ile Leu Lys Ala Trp Asp Phe Leu Ser 
            20                  25                  30          


Glu Asn Gln Leu Gln Thr Val Asn Phe Arg Gln Arg Lys Glu Ser Val 
        35                  40                  45              


Val Gln His Leu Ile His Leu Cys Glu Glu Lys Arg Ala Ser Ile Ser 
    50                  55                  60                  


Asp Ala Ala Leu Leu Asp Ile Ile Tyr Met Gln Phe His Gln His Gln 
65                  70                  75                  80  


Lys Val Trp Glu Val Phe Gln Met Ser Lys Gly Pro Gly Glu Asp Val 
                85                  90                  95      


Asp Leu Phe Asp Met Lys Gln Phe Lys Asn Ser Phe Lys Lys Ile Leu 
            100                 105                 110         


Gln Arg Ala Leu Lys Asn Val Thr Val Ser Phe Arg Glu Thr Glu Glu 
        115                 120                 125             


Asn Ala Val Trp Ile Arg Ile Ala Trp Gly Thr Gln Tyr Thr Lys Pro 
    130                 135                 140                 


Asn Gln Tyr Lys Pro Thr Tyr Val Val Tyr Tyr Ser Gln Thr Pro Tyr 
145                 150                 155                 160 


Ala Phe Thr Ser Ser Ser Met Leu Arg Arg Asn Thr Pro Leu Leu Gly 
                165                 170                 175     


Gln Glu Leu Glu Ala Thr Gly Lys Ile Tyr Leu Arg Gln Glu Glu Ile 
            180                 185                 190         


Ile Leu Asp Ile Thr Glu Met Lys Lys Ala Cys Asn 
        195                 200                 


<210>  3117
<211>  364
<212>  PRT
<213>  homo sapiens

<400>  3117

Met Ala Leu Ala Leu Leu Glu Asp Trp Cys Arg Ile Met Ser Val Asp 
1               5                   10                  15      


Glu Gln Lys Ser Leu Met Val Thr Gly Ile Pro Ala Asp Phe Glu Glu 
            20                  25                  30          


Ala Glu Ile Gln Glu Val Leu Gln Glu Thr Leu Lys Ser Leu Gly Arg 
        35                  40                  45              


Tyr Arg Leu Leu Gly Lys Ile Phe Arg Lys Gln Glu Asn Ala Asn Ala 
    50                  55                  60                  


Val Leu Leu Glu Leu Leu Glu Asp Thr Asp Val Ser Ala Ile Pro Ser 
65                  70                  75                  80  


Glu Val Gln Gly Lys Gly Gly Val Trp Lys Val Ile Phe Lys Thr Pro 
                85                  90                  95      


Asn Gln Asp Thr Glu Phe Leu Glu Arg Leu Asn Leu Phe Leu Glu Lys 
            100                 105                 110         


Glu Gly Gln Thr Val Ser Gly Met Phe Arg Ala Leu Gly Gln Glu Gly 
        115                 120                 125             


Val Ser Pro Ala Thr Val Pro Cys Ile Ser Pro Glu Leu Leu Ala His 
    130                 135                 140                 


Leu Leu Gly Gln Ala Met Ala His Ala Pro Gln Pro Leu Leu Pro Met 
145                 150                 155                 160 


Arg Tyr Arg Lys Leu Arg Val Phe Ser Gly Ser Ala Val Pro Ala Pro 
                165                 170                 175     


Glu Glu Glu Ser Phe Glu Val Trp Leu Glu Gln Ala Thr Glu Ile Val 
            180                 185                 190         


Lys Glu Trp Pro Val Thr Glu Ala Glu Lys Lys Arg Trp Leu Ala Glu 
        195                 200                 205             


Ser Leu Arg Gly Pro Ala Leu Asp Leu Met His Ile Val Gln Ala Asp 
    210                 215                 220                 


Asn Pro Ser Ile Ser Val Glu Glu Cys Leu Glu Ala Phe Lys Gln Val 
225                 230                 235                 240 


Phe Gly Ser Leu Glu Ser Arg Arg Thr Ala Gln Val Arg Tyr Leu Lys 
                245                 250                 255     


Thr Tyr Gln Glu Glu Gly Glu Lys Val Ser Ala Tyr Val Leu Arg Leu 
            260                 265                 270         


Glu Thr Leu Leu Arg Arg Ala Val Glu Lys Arg Ala Ile Pro Arg Arg 
        275                 280                 285             


Ile Ala Asp Gln Val Arg Leu Glu Gln Val Met Ala Gly Ala Thr Leu 
    290                 295                 300                 


Asn Gln Met Leu Trp Cys Arg Leu Arg Glu Leu Lys Asp Gln Gly Pro 
305                 310                 315                 320 


Pro Pro Ser Phe Leu Glu Leu Met Lys Val Ile Arg Glu Glu Glu Glu 
                325                 330                 335     


Glu Glu Ala Ser Phe Glu Asn Glu Ser Ile Glu Glu Pro Glu Glu Arg 
            340                 345                 350         


Asp Gly Tyr Gly Arg Trp Asn His Glu Gly Asp Asp 
        355                 360                 


<210>  3118
<211>  399
<212>  PRT
<213>  homo sapiens

<400>  3118

Met Lys Met Arg Phe Leu Gly Leu Val Val Cys Leu Val Leu Trp Thr 
1               5                   10                  15      


Leu His Ser Glu Gly Ser Gly Gly Lys Leu Thr Ala Val Asp Pro Glu 
            20                  25                  30          


Thr Asn Met Asn Val Ser Glu Ile Ile Ser Tyr Trp Gly Phe Pro Ser 
        35                  40                  45              


Glu Glu Tyr Leu Val Glu Thr Glu Asp Gly Tyr Ile Leu Cys Leu Asn 
    50                  55                  60                  


Arg Ile Pro His Gly Arg Lys Asn His Ser Asp Lys Gly Pro Lys Pro 
65                  70                  75                  80  


Val Val Phe Leu Gln His Gly Leu Leu Ala Asp Ser Ser Asn Trp Val 
                85                  90                  95      


Thr Asn Leu Ala Asn Ser Ser Leu Gly Phe Ile Leu Ala Asp Ala Gly 
            100                 105                 110         


Phe Asp Val Trp Met Gly Asn Ser Arg Gly Asn Thr Trp Ser Arg Lys 
        115                 120                 125             


His Lys Thr Leu Ser Val Ser Gln Asp Glu Phe Trp Ala Phe Ser Tyr 
    130                 135                 140                 


Asp Glu Met Ala Lys Tyr Asp Leu Pro Ala Ser Ile Asn Phe Ile Leu 
145                 150                 155                 160 


Asn Lys Thr Gly Gln Glu Gln Val Tyr Tyr Val Gly His Ser Gln Gly 
                165                 170                 175     


Thr Thr Ile Gly Phe Ile Ala Phe Ser Gln Ile Pro Glu Leu Ala Lys 
            180                 185                 190         


Arg Ile Lys Met Phe Phe Ala Leu Gly Pro Val Ala Ser Val Ala Phe 
        195                 200                 205             


Cys Thr Ser Pro Met Ala Lys Leu Gly Arg Leu Pro Asp His Leu Ile 
    210                 215                 220                 


Lys Asp Leu Phe Gly Asp Lys Glu Phe Leu Pro Gln Ser Ala Phe Leu 
225                 230                 235                 240 


Lys Trp Leu Gly Thr His Val Cys Thr His Val Ile Leu Lys Glu Leu 
                245                 250                 255     


Cys Gly Asn Leu Cys Phe Leu Leu Cys Gly Phe Asn Glu Arg Asn Leu 
            260                 265                 270         


Asn Met Ser Arg Val Asp Val Tyr Thr Thr His Ser Pro Ala Gly Thr 
        275                 280                 285             


Ser Val Gln Asn Met Leu His Trp Ser Gln Ala Val Lys Phe Gln Lys 
    290                 295                 300                 


Phe Gln Ala Phe Asp Trp Gly Ser Ser Ala Lys Asn Tyr Phe His Tyr 
305                 310                 315                 320 


Asn Gln Ser Tyr Pro Pro Thr Tyr Asn Val Lys Asp Met Leu Val Pro 
                325                 330                 335     


Thr Ala Val Trp Ser Gly Gly His Asp Trp Leu Ala Asp Val Tyr Asp 
            340                 345                 350         


Val Asn Ile Leu Leu Thr Gln Ile Thr Asn Leu Val Phe His Glu Ser 
        355                 360                 365             


Ile Pro Glu Trp Glu His Leu Asp Phe Ile Trp Gly Leu Asp Ala Pro 
    370                 375                 380                 


Trp Arg Leu Tyr Asn Lys Ile Ile Asn Leu Met Arg Lys Tyr Gln 
385                 390                 395                 


<210>  3119
<211>  161
<212>  PRT
<213>  homo sapiens

<400>  3119

Met Ser Val Pro Gly Pro Tyr Gln Ala Ala Thr Gly Pro Ser Ser Ala 
1               5                   10                  15      


Pro Ser Ala Pro Pro Ser Tyr Glu Glu Thr Val Ala Val Asn Ser Tyr 
            20                  25                  30          


Tyr Pro Thr Pro Pro Ala Pro Met Pro Gly Pro Thr Thr Gly Leu Val 
        35                  40                  45              


Thr Gly Pro Asp Gly Lys Gly Met Asn Pro Pro Ser Tyr Tyr Thr Gln 
    50                  55                  60                  


Pro Ala Pro Ile Pro Asn Asn Asn Pro Ile Thr Val Gln Thr Val Tyr 
65                  70                  75                  80  


Val Gln His Pro Ile Thr Phe Leu Asp Arg Pro Ile Gln Met Cys Cys 
                85                  90                  95      


Pro Ser Cys Asn Lys Met Ile Val Ser Gln Leu Ser Tyr Asn Ala Gly 
            100                 105                 110         


Ala Leu Thr Trp Leu Ser Cys Gly Ser Leu Cys Leu Leu Gly Cys Ile 
        115                 120                 125             


Ala Gly Cys Cys Phe Ile Pro Phe Cys Val Asp Ala Leu Gln Asp Val 
    130                 135                 140                 


Asp His Tyr Cys Pro Asn Cys Arg Ala Leu Leu Gly Thr Tyr Lys Arg 
145                 150                 155                 160 


Leu 
    


<210>  3120
<211>  224
<212>  PRT
<213>  homo sapiens

<400>  3120

Met Pro Arg Pro Gly Ser Ala Gln Arg Trp Ala Ala Val Ala Gly Arg 
1               5                   10                  15      


Trp Gly Cys Arg Leu Leu Ala Leu Leu Leu Leu Val Pro Gly Pro Gly 
            20                  25                  30          


Gly Ala Ser Glu Ile Thr Phe Glu Leu Pro Asp Asn Ala Lys Gln Cys 
        35                  40                  45              


Phe Tyr Glu Asp Ile Ala Gln Gly Thr Lys Cys Thr Leu Glu Phe Gln 
    50                  55                  60                  


Val Ile Thr Gly Gly His Tyr Asp Val Asp Cys Arg Leu Glu Asp Pro 
65                  70                  75                  80  


Asp Gly Lys Val Leu Tyr Lys Glu Met Lys Lys Gln Tyr Asp Ser Phe 
                85                  90                  95      


Thr Phe Thr Ala Ser Lys Asn Gly Thr Tyr Lys Phe Cys Phe Ser Asn 
            100                 105                 110         


Glu Phe Ser Thr Phe Thr His Lys Thr Val Tyr Phe Asp Phe Gln Val 
        115                 120                 125             


Gly Glu Asp Pro Pro Leu Phe Pro Ser Glu Asn Arg Val Ser Ala Leu 
    130                 135                 140                 


Thr Gln Met Glu Ser Ala Cys Val Ser Ile His Glu Ala Leu Lys Ser 
145                 150                 155                 160 


Val Ile Asp Tyr Gln Thr His Phe Arg Leu Arg Glu Ala Gln Gly Arg 
                165                 170                 175     


Ser Arg Ala Glu Asp Leu Asn Thr Arg Val Ala Tyr Trp Ser Val Gly 
            180                 185                 190         


Glu Ala Leu Ile Leu Leu Val Val Ser Ile Gly Gln Val Phe Leu Leu 
        195                 200                 205             


Lys Ser Phe Phe Ser Asp Lys Arg Thr Thr Thr Thr Arg Val Gly Ser 
    210                 215                 220                 


<210>  3121
<211>  492
<212>  PRT
<213>  homo sapiens

<400>  3121

Met Ala Val Leu Leu Glu Thr Thr Leu Gly Asp Val Val Ile Asp Leu 
1               5                   10                  15      


Tyr Thr Glu Glu Arg Pro Arg Ala Cys Leu Asn Phe Leu Lys Leu Cys 
            20                  25                  30          


Lys Ile Lys Tyr Tyr Asn Tyr Cys Leu Ile His Asn Val Gln Arg Asp 
        35                  40                  45              


Phe Ile Ile Gln Thr Gly Asp Pro Thr Gly Thr Gly Arg Gly Gly Glu 
    50                  55                  60                  


Ser Ile Phe Gly Gln Leu Tyr Gly Asp Gln Ala Ser Phe Phe Glu Ala 
65                  70                  75                  80  


Glu Lys Val Pro Arg Ile Lys His Lys Lys Lys Gly Thr Val Ser Met 
                85                  90                  95      


Val Asn Asn Gly Ser Asp Gln His Gly Ser Gln Phe Leu Ile Thr Thr 
            100                 105                 110         


Gly Glu Asn Leu Asp Tyr Leu Asp Gly Val His Thr Val Phe Gly Glu 
        115                 120                 125             


Val Thr Glu Gly Met Asp Ile Ile Lys Lys Ile Asn Glu Thr Phe Val 
    130                 135                 140                 


Asp Lys Asp Phe Val Pro Tyr Gln Asp Ile Arg Ile Asn His Thr Val 
145                 150                 155                 160 


Ile Leu Asp Asp Pro Phe Asp Asp Pro Pro Asp Leu Leu Ile Pro Asp 
                165                 170                 175     


Arg Ser Pro Glu Pro Thr Arg Glu Gln Leu Asp Ser Gly Arg Ile Gly 
            180                 185                 190         


Ala Asp Glu Glu Ile Asp Asp Phe Lys Gly Arg Ser Ala Glu Glu Val 
        195                 200                 205             


Glu Glu Ile Lys Ala Glu Lys Glu Ala Lys Thr Gln Ala Ile Leu Leu 
    210                 215                 220                 


Glu Met Val Gly Asp Leu Pro Asp Ala Asp Ile Lys Pro Pro Glu Asn 
225                 230                 235                 240 


Val Leu Phe Val Cys Lys Leu Asn Pro Val Thr Thr Asp Glu Asp Leu 
                245                 250                 255     


Glu Ile Ile Phe Ser Arg Phe Gly Pro Ile Arg Ser Cys Glu Val Ile 
            260                 265                 270         


Arg Asp Trp Lys Thr Gly Glu Ser Leu Cys Tyr Ala Phe Ile Glu Phe 
        275                 280                 285             


Glu Lys Glu Glu Asp Cys Glu Lys Ala Phe Phe Lys Met Asp Asn Val 
    290                 295                 300                 


Leu Ile Asp Asp Arg Arg Ile His Val Asp Phe Ser Gln Ser Val Ala 
305                 310                 315                 320 


Lys Val Lys Trp Lys Gly Lys Gly Gly Lys Tyr Thr Lys Ser Asp Phe 
                325                 330                 335     


Lys Glu Tyr Glu Lys Glu Gln Asp Lys Pro Pro Asn Leu Val Leu Lys 
            340                 345                 350         


Asp Lys Val Lys Pro Lys Gln Asp Thr Lys Tyr Asp Leu Ile Leu Asp 
        355                 360                 365             


Glu Gln Ala Glu Asp Ser Lys Ser Ser His Ser His Thr Ser Lys Lys 
    370                 375                 380                 


His Lys Lys Lys Thr His His Cys Ser Glu Glu Lys Glu Asp Glu Asp 
385                 390                 395                 400 


Tyr Met Pro Ile Lys Asn Thr Asn Gln Asp Ile Tyr Arg Glu Met Gly 
                405                 410                 415     


Phe Gly His Tyr Glu Glu Glu Glu Ser Cys Trp Glu Lys Gln Lys Ser 
            420                 425                 430         


Glu Lys Arg Asp Arg Thr Gln Asn Arg Ser Arg Ser Arg Ser Arg Glu 
        435                 440                 445             


Arg Asp Gly His Tyr Ser Asn Ser His Lys Ser Lys Tyr Gln Thr Asp 
    450                 455                 460                 


Leu Tyr Glu Arg Glu Arg Ser Lys Lys Arg Asp Arg Ser Arg Ser Pro 
465                 470                 475                 480 


Lys Lys Ser Lys Asp Lys Glu Lys Ser Lys Tyr Arg 
                485                 490         


<210>  3122
<211>  223
<212>  PRT
<213>  homo sapiens

<400>  3122

Met Lys Leu His Tyr Val Ala Val Leu Thr Leu Ala Ile Leu Met Phe 
1               5                   10                  15      


Leu Thr Trp Leu Pro Glu Ser Leu Ser Cys Asn Lys Ala Leu Cys Ala 
            20                  25                  30          


Ser Asp Val Ser Lys Cys Leu Ile Gln Glu Leu Cys Gln Cys Arg Pro 
        35                  40                  45              


Gly Glu Gly Asn Cys Ser Cys Cys Lys Glu Cys Met Leu Cys Leu Gly 
    50                  55                  60                  


Ala Leu Trp Asp Glu Cys Cys Asp Cys Val Gly Met Cys Asn Pro Arg 
65                  70                  75                  80  


Asn Tyr Ser Asp Thr Pro Pro Thr Ser Lys Ser Thr Val Glu Glu Leu 
                85                  90                  95      


His Glu Pro Ile Pro Ser Leu Phe Arg Ala Leu Thr Glu Gly Asp Thr 
            100                 105                 110         


Gln Leu Asn Trp Asn Ile Val Ser Phe Pro Val Ala Glu Glu Leu Ser 
        115                 120                 125             


His His Glu Asn Leu Val Ser Phe Leu Glu Thr Val Asn Gln Pro His 
    130                 135                 140                 


His Gln Asn Val Ser Val Pro Ser Asn Asn Val His Ala Pro Tyr Ser 
145                 150                 155                 160 


Ser Asp Lys Glu His Met Cys Thr Val Val Tyr Phe Asp Asp Cys Met 
                165                 170                 175     


Ser Ile His Gln Cys Lys Ile Ser Cys Glu Ser Met Gly Ala Ser Lys 
            180                 185                 190         


Tyr Arg Trp Phe His Asn Ala Cys Cys Glu Cys Ile Gly Pro Glu Cys 
        195                 200                 205             


Ile Asp Tyr Gly Ser Lys Thr Val Lys Cys Met Asn Cys Met Phe 
    210                 215                 220             


<210>  3123
<211>  447
<212>  PRT
<213>  homo sapiens

<400>  3123

Met Leu Leu Asp Ala Gly Pro Gln Tyr Pro Ala Ile Gly Val Thr Thr 
1               5                   10                  15      


Phe Gly Ala Ser Arg His His Ser Ala Gly Asp Val Ala Glu Arg Asp 
            20                  25                  30          


Val Gly Leu Gly Ile Asn Pro Phe Ala Asp Gly Met Gly Ala Phe Lys 
        35                  40                  45              


Leu Asn Pro Ser Ser His Glu Leu Ala Ser Ala Gly Gln Thr Ala Phe 
    50                  55                  60                  


Thr Ser Gln Ala Pro Gly Tyr Ala Ala Ala Ala Ala Leu Gly His His 
65                  70                  75                  80  


His His Pro Gly His Val Gly Ser Tyr Ser Ser Ala Ala Phe Asn Ser 
                85                  90                  95      


Thr Arg Asp Phe Leu Phe Arg Asn Arg Gly Phe Gly Asp Ala Ala Ala 
            100                 105                 110         


Ala Ala Ser Ala Gln His Ser Leu Phe Ala Ala Ser Ala Gly Gly Phe 
        115                 120                 125             


Gly Gly Pro His Gly His Thr Asp Ala Ala Gly His Leu Leu Phe Pro 
    130                 135                 140                 


Gly Leu His Glu Gln Ala Ala Gly His Ala Ser Pro Asn Val Val Asn 
145                 150                 155                 160 


Gly Gln Met Arg Leu Gly Phe Ser Gly Asp Met Tyr Pro Arg Pro Glu 
                165                 170                 175     


Gln Tyr Gly Gln Val Thr Ser Pro Arg Ser Glu His Tyr Ala Ala Pro 
            180                 185                 190         


Gln Leu His Gly Tyr Gly Pro Met Asn Val Asn Met Ala Ala His His 
        195                 200                 205             


Gly Ala Gly Ala Phe Phe Arg Tyr Met Arg Gln Pro Ile Lys Gln Glu 
    210                 215                 220                 


Leu Ile Cys Lys Trp Ile Glu Pro Glu Gln Leu Ala Asn Pro Lys Lys 
225                 230                 235                 240 


Ser Cys Asn Lys Thr Phe Ser Thr Met His Glu Leu Val Thr His Val 
                245                 250                 255     


Thr Val Glu His Val Gly Gly Pro Glu Gln Ser Asn His Ile Cys Phe 
            260                 265                 270         


Trp Glu Glu Cys Pro Arg Glu Gly Lys Pro Phe Lys Ala Lys Tyr Lys 
        275                 280                 285             


Leu Val Asn His Ile Arg Val His Thr Gly Glu Lys Pro Phe Pro Cys 
    290                 295                 300                 


Pro Phe Pro Gly Cys Gly Lys Val Phe Ala Arg Ser Glu Asn Leu Lys 
305                 310                 315                 320 


Ile His Lys Arg Thr His Thr Gly Glu Lys Pro Phe Lys Cys Glu Phe 
                325                 330                 335     


Glu Gly Cys Asp Arg Arg Phe Ala Asn Ser Ser Asp Arg Lys Lys His 
            340                 345                 350         


Met His Val His Thr Ser Asp Lys Pro Tyr Leu Cys Lys Met Cys Asp 
        355                 360                 365             


Lys Ser Tyr Thr His Pro Ser Ser Leu Arg Lys His Met Lys Val His 
    370                 375                 380                 


Glu Ser Ser Ser Gln Gly Ser Gln Pro Ser Pro Ala Ala Ser Ser Gly 
385                 390                 395                 400 


Tyr Glu Ser Ser Thr Pro Pro Thr Ile Val Ser Pro Ser Thr Asp Asn 
                405                 410                 415     


Pro Thr Thr Ser Ser Leu Ser Pro Ser Ser Ser Ala Val His His Thr 
            420                 425                 430         


Ala Gly His Ser Ala Leu Ser Ser Asn Phe Asn Glu Trp Tyr Val 
        435                 440                 445         


<210>  3124
<211>  428
<212>  PRT
<213>  homo sapiens

<400>  3124

Met Asp Pro Ser Val Thr Leu Trp Gln Phe Leu Leu Gln Leu Leu Arg 
1               5                   10                  15      


Glu Gln Gly Asn Gly His Ile Ile Ser Trp Thr Ser Arg Asp Gly Gly 
            20                  25                  30          


Glu Phe Lys Leu Val Asp Ala Glu Glu Val Ala Arg Leu Trp Gly Leu 
        35                  40                  45              


Arg Lys Asn Lys Thr Asn Met Asn Tyr Asp Lys Leu Ser Arg Ala Leu 
    50                  55                  60                  


Arg Tyr Tyr Tyr Asp Lys Asn Ile Ile Arg Lys Val Ser Gly Gln Lys 
65                  70                  75                  80  


Phe Val Tyr Lys Phe Val Ser Tyr Pro Glu Val Ala Gly Cys Ser Thr 
                85                  90                  95      


Glu Asp Cys Pro Pro Gln Pro Glu Val Ser Val Thr Ser Thr Met Pro 
            100                 105                 110         


Asn Val Ala Pro Ala Ala Ile His Ala Ala Pro Gly Asp Thr Val Ser 
        115                 120                 125             


Gly Lys Pro Gly Thr Pro Lys Gly Ala Gly Met Ala Gly Pro Gly Gly 
    130                 135                 140                 


Leu Ala Arg Ser Ser Arg Asn Glu Tyr Met Arg Ser Gly Leu Tyr Ser 
145                 150                 155                 160 


Thr Phe Thr Ile Gln Ser Leu Gln Pro Gln Pro Pro Pro His Pro Arg 
                165                 170                 175     


Pro Ala Val Val Leu Pro Ser Ala Ala Pro Ala Gly Ala Ala Ala Pro 
            180                 185                 190         


Pro Ser Gly Ser Arg Ser Thr Ser Pro Ser Pro Leu Glu Ala Cys Leu 
        195                 200                 205             


Glu Ala Glu Glu Ala Gly Leu Pro Leu Gln Val Ile Leu Thr Pro Pro 
    210                 215                 220                 


Glu Ala Pro Asn Leu Lys Ser Glu Glu Leu Asn Val Glu Pro Gly Leu 
225                 230                 235                 240 


Gly Arg Ala Leu Pro Pro Glu Val Lys Val Glu Gly Pro Lys Glu Glu 
                245                 250                 255     


Leu Glu Val Ala Gly Glu Arg Gly Phe Val Pro Glu Thr Thr Lys Ala 
            260                 265                 270         


Glu Pro Glu Val Pro Pro Gln Glu Gly Val Pro Ala Arg Leu Pro Ala 
        275                 280                 285             


Val Val Met Asp Thr Ala Gly Gln Ala Gly Gly His Ala Ala Ser Ser 
    290                 295                 300                 


Pro Glu Ile Ser Gln Pro Gln Lys Gly Arg Lys Pro Arg Asp Leu Glu 
305                 310                 315                 320 


Leu Pro Leu Ser Pro Ser Leu Leu Gly Gly Pro Gly Pro Glu Arg Thr 
                325                 330                 335     


Pro Gly Ser Gly Ser Gly Ser Gly Leu Gln Ala Pro Gly Pro Ala Leu 
            340                 345                 350         


Thr Pro Ser Leu Leu Pro Thr His Thr Leu Thr Pro Val Leu Leu Thr 
        355                 360                 365             


Pro Ser Ser Leu Pro Pro Ser Ile His Phe Trp Ser Thr Leu Ser Pro 
    370                 375                 380                 


Ile Ala Pro Arg Ser Pro Ala Lys Leu Ser Phe Gln Phe Pro Ser Ser 
385                 390                 395                 400 


Gly Ser Ala Gln Val His Ile Pro Ser Ile Ser Val Asp Gly Leu Ser 
                405                 410                 415     


Thr Pro Val Val Leu Ser Pro Gly Pro Gln Lys Pro 
            420                 425             


<210>  3125
<211>  1392
<212>  PRT
<213>  homo sapiens

<400>  3125

Met Val Glu Pro Gly Gln Asp Leu Leu Leu Ala Ala Leu Ser Glu Ser 
1               5                   10                  15      


Gly Ile Ser Pro Asn Asp Leu Phe Asp Ile Asp Gly Gly Asp Ala Gly 
            20                  25                  30          


Leu Ala Thr Pro Met Pro Thr Pro Ser Val Gln Gln Ser Val Pro Leu 
        35                  40                  45              


Ser Ala Leu Glu Leu Gly Leu Glu Thr Glu Ala Ala Val Pro Val Lys 
    50                  55                  60                  


Gln Glu Pro Glu Thr Val Pro Thr Pro Ala Leu Leu Asn Val Arg Gln 
65                  70                  75                  80  


Pro Pro Ser Thr Thr Thr Phe Val Leu Asn Gln Ile Asn His Leu Pro 
                85                  90                  95      


Pro Leu Gly Ser Thr Ile Val Met Thr Lys Thr Pro Pro Val Thr Thr 
            100                 105                 110         


Asn Arg Gln Thr Ile Thr Leu Thr Lys Phe Ile Gln Thr Thr Ala Ser 
        115                 120                 125             


Thr Arg Pro Ser Val Ser Ala Pro Thr Val Arg Asn Ala Met Thr Ser 
    130                 135                 140                 


Ala Pro Ser Lys Asp Gln Val Gln Leu Lys Asp Leu Leu Lys Asn Asn 
145                 150                 155                 160 


Ser Leu Asn Glu Leu Met Lys Leu Lys Pro Pro Ala Asn Ile Ala Gln 
                165                 170                 175     


Pro Val Ala Thr Ala Ala Thr Asp Val Ser Asn Gly Thr Val Lys Lys 
            180                 185                 190         


Glu Ser Ser Asn Lys Glu Gly Ala Arg Met Trp Ile Asn Asp Met Lys 
        195                 200                 205             


Met Arg Ser Phe Ser Pro Thr Met Lys Val Pro Val Val Lys Glu Asp 
    210                 215                 220                 


Asp Glu Pro Glu Glu Glu Asp Glu Glu Glu Met Gly His Ala Glu Thr 
225                 230                 235                 240 


Tyr Ala Glu Tyr Met Pro Ile Lys Leu Lys Ile Gly Leu Arg His Pro 
                245                 250                 255     


Asp Ala Val Val Glu Thr Ser Ser Leu Ser Ser Val Thr Pro Pro Asp 
            260                 265                 270         


Val Trp Tyr Lys Thr Ser Ile Ser Glu Glu Thr Ile Asp Asn Gly Trp 
        275                 280                 285             


Leu Ser Ala Leu Gln Leu Glu Ala Ile Thr Tyr Ala Ala Gln Gln His 
    290                 295                 300                 


Glu Thr Phe Leu Pro Asn Gly Asp Arg Ala Gly Phe Leu Ile Gly Asp 
305                 310                 315                 320 


Gly Ala Gly Val Gly Lys Gly Arg Thr Ile Ala Gly Ile Ile Tyr Glu 
                325                 330                 335     


Asn Tyr Leu Leu Ser Arg Lys Arg Ala Leu Trp Phe Ser Val Ser Asn 
            340                 345                 350         


Asp Leu Lys Tyr Asp Ala Glu Arg Asp Leu Arg Asp Ile Gly Ala Lys 
        355                 360                 365             


Asn Ile Leu Val His Ser Leu Asn Lys Phe Lys Tyr Gly Lys Ile Ser 
    370                 375                 380                 


Ser Lys His Asn Gly Ser Val Lys Lys Gly Val Ile Phe Ala Thr Tyr 
385                 390                 395                 400 


Ser Ser Leu Ile Gly Glu Ser Gln Ser Gly Gly Lys Tyr Lys Thr Arg 
                405                 410                 415     


Leu Lys Gln Leu Leu His Trp Cys Gly Asp Asp Phe Asp Gly Val Ile 
            420                 425                 430         


Val Phe Asp Glu Cys His Lys Ala Lys Asn Leu Cys Pro Val Gly Ser 
        435                 440                 445             


Ser Lys Pro Thr Lys Thr Gly Leu Ala Val Leu Glu Leu Gln Asn Lys 
    450                 455                 460                 


Leu Pro Lys Ala Arg Val Val Tyr Ala Ser Ala Thr Gly Ala Ser Glu 
465                 470                 475                 480 


Pro Arg Asn Met Ala Tyr Met Asn Arg Leu Gly Ile Trp Gly Glu Gly 
                485                 490                 495     


Thr Pro Phe Arg Glu Phe Ser Asp Phe Ile Gln Ala Val Glu Arg Arg 
            500                 505                 510         


Gly Val Gly Ala Met Glu Ile Val Ala Met Asp Met Lys Leu Arg Gly 
        515                 520                 525             


Met Tyr Ile Ala Arg Gln Leu Ser Phe Thr Gly Val Thr Phe Lys Ile 
    530                 535                 540                 


Glu Glu Val Leu Leu Ser Gln Ser Tyr Val Lys Met Tyr Asn Lys Ala 
545                 550                 555                 560 


Val Lys Leu Trp Val Ile Ala Arg Glu Arg Phe Gln Gln Ala Ala Asp 
                565                 570                 575     


Leu Ile Asp Ala Glu Gln Arg Met Lys Lys Ser Met Trp Gly Gln Phe 
            580                 585                 590         


Trp Ser Ala His Gln Arg Phe Phe Lys Tyr Leu Cys Ile Ala Ser Lys 
        595                 600                 605             


Val Lys Arg Val Val Gln Leu Ala Arg Glu Glu Ile Lys Asn Gly Lys 
    610                 615                 620                 


Cys Val Val Ile Gly Leu Gln Ser Thr Gly Glu Ala Arg Thr Leu Glu 
625                 630                 635                 640 


Ala Leu Glu Glu Gly Gly Gly Glu Leu Asn Asp Phe Val Ser Thr Ala 
                645                 650                 655     


Lys Gly Val Leu Gln Ser Leu Ile Glu Lys His Phe Pro Ala Pro Asp 
            660                 665                 670         


Arg Lys Lys Leu Tyr Ser Leu Leu Gly Ile Asp Leu Thr Ala Pro Ser 
        675                 680                 685             


Asn Asn Ser Ser Pro Arg Asp Ser Pro Cys Lys Glu Asn Lys Ile Lys 
    690                 695                 700                 


Lys Arg Lys Gly Glu Glu Ile Thr Arg Glu Ala Lys Lys Ala Arg Lys 
705                 710                 715                 720 


Val Gly Gly Leu Thr Gly Ser Ser Ser Asp Asp Ser Gly Ser Glu Ser 
                725                 730                 735     


Asp Ala Ser Asp Asn Glu Glu Ser Asp Tyr Glu Ser Ser Lys Asn Met 
            740                 745                 750         


Ser Ser Gly Asp Asp Asp Asp Phe Asn Pro Phe Leu Asp Glu Ser Asn 
        755                 760                 765             


Glu Asp Asp Glu Asn Asp Pro Trp Leu Ile Arg Lys Asp His Lys Lys 
    770                 775                 780                 


Asn Lys Glu Lys Lys Lys Lys Lys Ser Ile Asp Pro Asp Ser Ile Gln 
785                 790                 795                 800 


Ser Ala Leu Leu Ala Ser Gly Leu Gly Ser Lys Arg Pro Ser Phe Ser 
                805                 810                 815     


Ser Thr Pro Val Ile Ser Pro Ala Pro Asn Ser Thr Pro Ala Asn Ser 
            820                 825                 830         


Asn Thr Asn Ser Asn Ser Ser Leu Ile Thr Ser Gln Asp Ala Val Glu 
        835                 840                 845             


Arg Ala Gln Gln Met Lys Lys Asp Leu Leu Asp Lys Leu Glu Lys Leu 
    850                 855                 860                 


Ala Glu Asp Leu Pro Pro Asn Thr Leu Asp Glu Leu Ile Asp Glu Leu 
865                 870                 875                 880 


Gly Gly Pro Glu Asn Val Ala Glu Met Thr Gly Arg Lys Gly Arg Val 
                885                 890                 895     


Val Ser Asn Asp Asp Gly Ser Ile Ser Tyr Glu Ser Arg Ser Glu Leu 
            900                 905                 910         


Asp Val Pro Val Glu Ile Leu Asn Ile Thr Glu Lys Gln Arg Phe Met 
        915                 920                 925             


Asp Gly Asp Lys Asn Ile Ala Ile Ile Ser Glu Ala Ala Ser Ser Gly 
    930                 935                 940                 


Ile Ser Leu Gln Ala Asp Arg Arg Ala Lys Asn Gln Arg Arg Arg Val 
945                 950                 955                 960 


His Met Thr Leu Glu Leu Pro Trp Ser Ala Asp Arg Ala Ile Gln Gln 
                965                 970                 975     


Phe Gly Arg Thr His Arg Ser Asn Gln Val Thr Ala Pro Glu Tyr Val 
            980                 985                 990         


Phe Leu Ile Ser Glu Leu Ala Gly  Glu Gln Arg Phe Ala  Ser Ile Val 
        995                 1000                 1005             


Ala Lys  Arg Leu Glu Ser Leu  Gly Ala Leu Thr His  Gly Asp Arg 
    1010                 1015                 1020             


Arg Ala  Thr Glu Ser Arg Asp  Leu Ser Arg Phe Asn  Phe Asp Asn 
    1025                 1030                 1035             


Lys Tyr  Gly Arg Asn Ala Leu  Glu Ile Val Met Lys  Ser Ile Val 
    1040                 1045                 1050             


Asn Leu  Asp Ser Pro Met Val  Ser Pro Pro Pro Asp  Tyr Pro Gly 
    1055                 1060                 1065             


Glu Phe  Phe Lys Asp Val Arg  Gln Gly Leu Ile Gly  Val Gly Leu 
    1070                 1075                 1080             


Ile Asn  Val Glu Asp Arg Ser  Gly Ile Leu Thr Leu  Asp Lys Asp 
    1085                 1090                 1095             


Tyr Asn  Asn Ile Gly Lys Phe  Leu Asn Arg Ile Leu  Gly Met Glu 
    1100                 1105                 1110             


Val His  Gln Gln Asn Ala Leu  Phe Gln Tyr Phe Ala  Asp Thr Leu 
    1115                 1120                 1125             


Thr Ala  Val Val Gln Asn Ala  Lys Lys Asn Gly Arg  Tyr Asp Met 
    1130                 1135                 1140             


Gly Ile  Leu Asp Leu Gly Ser  Gly Asp Glu Lys Val  Arg Lys Ser 
    1145                 1150                 1155             


Asp Val  Lys Lys Phe Leu Thr  Pro Gly Tyr Ser Thr  Ser Gly His 
    1160                 1165                 1170             


Val Glu  Leu Tyr Thr Ile Ser  Val Glu Arg Gly Met  Ser Trp Glu 
    1175                 1180                 1185             


Glu Ala  Thr Lys Ile Trp Ala  Glu Leu Thr Gly Pro  Asp Asp Gly 
    1190                 1195                 1200             


Phe Tyr  Leu Ser Leu Gln Ile  Arg Asn Asn Lys Lys  Thr Ala Ile 
    1205                 1210                 1215             


Leu Val  Lys Glu Val Asn Pro  Lys Lys Lys Leu Phe  Leu Val Tyr 
    1220                 1225                 1230             


Arg Pro  Asn Thr Gly Lys Gln  Leu Lys Leu Glu Ile  Tyr Ala Asp 
    1235                 1240                 1245             


Leu Lys  Lys Lys Tyr Lys Lys  Val Val Ser Asp Asp  Ala Leu Met 
    1250                 1255                 1260             


His Trp  Leu Asp Gln Tyr Asn  Ser Ser Ala Asp Thr  Cys Thr His 
    1265                 1270                 1275             


Ala Tyr  Trp Arg Gly Asn Cys  Lys Lys Ala Ser Leu  Gly Leu Val 
    1280                 1285                 1290             


Cys Glu  Ile Gly Leu Arg Cys  Arg Thr Tyr Tyr Val  Leu Cys Gly 
    1295                 1300                 1305             


Ser Val  Leu Ser Val Trp Thr  Lys Val Glu Gly Val  Leu Ala Ser 
    1310                 1315                 1320             


Val Ser  Gly Thr Asn Val Lys  Met Gln Ile Val Arg  Leu Arg Thr 
    1325                 1330                 1335             


Glu Asp  Gly Gln Arg Ile Val  Gly Leu Ile Ile Pro  Ala Asn Cys 
    1340                 1345                 1350             


Val Ser  Pro Leu Val Asn Leu  Leu Ser Thr Ser Asp  Gln Ser Gln 
    1355                 1360                 1365             


Gln Leu  Ala Val Gln Gln Lys  Gln Leu Trp Gln Gln  His His Pro 
    1370                 1375                 1380             


Gln Ser  Ile Thr Asn Leu Ser  Asn Ala 
    1385                 1390         


<210>  3126
<211>  361
<212>  PRT
<213>  homo sapiens

<400>  3126

Met Ala Thr Ala Ala Ser Asn Pro Tyr Ser Ile Leu Ser Ser Thr Ser 
1               5                   10                  15      


Leu Val His Ala Asp Ser Ala Gly Met Gln Gln Gly Ser Pro Phe Arg 
            20                  25                  30          


Asn Pro Gln Lys Leu Leu Gln Ser Asp Tyr Leu Gln Gly Val Pro Ser 
        35                  40                  45              


Asn Gly His Pro Leu Gly His His Trp Val Thr Ser Leu Ser Asp Gly 
    50                  55                  60                  


Gly Pro Trp Ser Ser Thr Leu Ala Thr Ser Pro Leu Asp Gln Gln Asp 
65                  70                  75                  80  


Val Lys Pro Gly Arg Glu Asp Leu Gln Leu Gly Ala Ile Ile His His 
                85                  90                  95      


Arg Ser Pro His Val Ala His His Ser Pro His Thr Asn His Pro Asn 
            100                 105                 110         


Ala Trp Gly Ala Ser Pro Ala Pro Asn Pro Ser Ile Thr Ser Ser Gly 
        115                 120                 125             


Gln Pro Leu Asn Val Tyr Ser Gln Pro Gly Phe Thr Val Ser Gly Met 
    130                 135                 140                 


Leu Glu His Gly Gly Leu Thr Pro Pro Pro Ala Ala Ala Ser Ala Gln 
145                 150                 155                 160 


Ser Leu His Pro Val Leu Arg Glu Pro Pro Asp His Gly Glu Leu Gly 
                165                 170                 175     


Ser His His Cys Gln Asp His Ser Asp Glu Glu Thr Pro Thr Ser Asp 
            180                 185                 190         


Glu Leu Glu Gln Phe Ala Lys Gln Phe Lys Gln Arg Arg Ile Lys Leu 
        195                 200                 205             


Gly Phe Thr Gln Ala Asp Val Gly Leu Ala Leu Gly Thr Leu Tyr Gly 
    210                 215                 220                 


Asn Val Phe Ser Gln Thr Thr Ile Cys Arg Phe Glu Ala Leu Gln Leu 
225                 230                 235                 240 


Ser Phe Lys Asn Met Cys Lys Leu Lys Pro Leu Leu Asn Lys Trp Leu 
                245                 250                 255     


Glu Glu Ala Asp Ser Ser Thr Gly Ser Pro Thr Ser Ile Asp Lys Ile 
            260                 265                 270         


Ala Ala Gln Gly Arg Lys Arg Lys Lys Arg Thr Ser Ile Glu Val Ser 
        275                 280                 285             


Val Lys Gly Val Leu Glu Thr His Phe Leu Lys Cys Pro Lys Pro Ala 
    290                 295                 300                 


Ala Gln Glu Ile Ser Ser Leu Ala Asp Ser Leu Gln Leu Glu Lys Glu 
305                 310                 315                 320 


Val Val Arg Val Trp Phe Cys Asn Arg Arg Gln Lys Glu Lys Arg Met 
                325                 330                 335     


Thr Pro Pro Gly Asp Gln Gln Pro His Glu Val Tyr Ser His Thr Val 
            340                 345                 350         


Lys Thr Asp Thr Ser Cys His Asp Leu 
        355                 360     


<210>  3127
<211>  187
<212>  PRT
<213>  homo sapiens

<400>  3127

Met Ser Glu Met Ala Glu Leu Ser Glu Leu Tyr Glu Glu Ser Ser Asp 
1               5                   10                  15      


Leu Gln Met Asp Val Met Pro Gly Glu Gly Asp Leu Pro Gln Met Glu 
            20                  25                  30          


Val Gly Ser Gly Ser Arg Glu Leu Ser Leu Arg Pro Ser Arg Ser Gly 
        35                  40                  45              


Ala Gln Gln Leu Glu Glu Glu Gly Pro Met Glu Glu Glu Glu Ala Gln 
    50                  55                  60                  


Pro Met Ala Ala Pro Glu Gly Lys Arg Ser Leu Ala Asn Gly Pro Asn 
65                  70                  75                  80  


Ala Gly Glu Gln Pro Gly Gln Val Ala Gly Ala Asp Phe Glu Ser Glu 
                85                  90                  95      


Asp Glu Gly Glu Glu Phe Asp Asp Trp Glu Asp Asp Tyr Asp Tyr Pro 
            100                 105                 110         


Glu Glu Glu Gln Leu Ser Gly Ala Gly Tyr Arg Val Ser Ala Ala Leu 
        115                 120                 125             


Glu Glu Ala Asp Lys Met Phe Leu Arg Thr Arg Glu Pro Ala Leu Asp 
    130                 135                 140                 


Gly Gly Phe Gln Met His Tyr Glu Lys Thr Pro Phe Asp Gln Leu Ala 
145                 150                 155                 160 


Phe Ile Glu Glu Leu Phe Ser Leu Met Val Val Asn Arg Leu Thr Glu 
                165                 170                 175     


Glu Leu Gly Cys Asp Glu Ile Ile Asp Arg Glu 
            180                 185         


<210>  3128
<211>  619
<212>  PRT
<213>  homo sapiens

<400>  3128

Met Ala Arg Gln Pro Pro Pro Pro Trp Val His Ala Ala Phe Leu Leu 
1               5                   10                  15      


Cys Leu Leu Ser Leu Gly Gly Ala Ile Glu Ile Pro Met Asp Pro Ser 
            20                  25                  30          


Ile Gln Asn Glu Leu Thr Gln Pro Pro Thr Ile Thr Lys Gln Ser Ala 
        35                  40                  45              


Lys Asp His Ile Val Asp Pro Arg Asp Asn Ile Leu Ile Glu Cys Glu 
    50                  55                  60                  


Ala Lys Gly Asn Pro Ala Pro Ser Phe His Trp Thr Arg Asn Ser Arg 
65                  70                  75                  80  


Phe Phe Asn Ile Ala Lys Asp Pro Arg Val Ser Met Arg Arg Arg Ser 
                85                  90                  95      


Gly Thr Leu Val Ile Asp Phe Arg Ser Gly Gly Arg Pro Glu Glu Tyr 
            100                 105                 110         


Glu Gly Glu Tyr Gln Cys Phe Ala Arg Asn Lys Phe Gly Thr Ala Leu 
        115                 120                 125             


Ser Asn Arg Ile Arg Leu Gln Val Ser Lys Ser Pro Leu Trp Pro Lys 
    130                 135                 140                 


Glu Asn Leu Asp Pro Val Val Val Gln Glu Gly Ala Pro Leu Thr Leu 
145                 150                 155                 160 


Gln Cys Asn Pro Pro Pro Gly Leu Pro Ser Pro Val Ile Phe Trp Met 
                165                 170                 175     


Ser Ser Ser Met Glu Pro Ile Thr Gln Asp Lys Arg Val Ser Gln Gly 
            180                 185                 190         


His Asn Gly Asp Leu Tyr Phe Ser Asn Val Met Leu Gln Asp Met Gln 
        195                 200                 205             


Thr Asp Tyr Ser Cys Asn Ala Arg Phe His Phe Thr His Thr Ile Gln 
    210                 215                 220                 


Gln Lys Asn Pro Phe Thr Leu Lys Val Leu Thr Thr Arg Gly Val Ala 
225                 230                 235                 240 


Glu Arg Thr Pro Ser Phe Met Tyr Pro Gln Gly Thr Ala Ser Ser Gln 
                245                 250                 255     


Met Val Leu Arg Gly Met Asp Leu Leu Leu Glu Cys Ile Ala Ser Gly 
            260                 265                 270         


Val Pro Thr Pro Asp Ile Ala Trp Tyr Lys Lys Gly Gly Asp Leu Pro 
        275                 280                 285             


Ser Asp Lys Ala Lys Phe Glu Asn Phe Asn Lys Ala Leu Arg Ile Thr 
    290                 295                 300                 


Asn Val Ser Glu Glu Asp Ser Gly Glu Tyr Phe Cys Leu Ala Ser Asn 
305                 310                 315                 320 


Lys Met Gly Ser Ile Arg His Thr Ile Ser Val Arg Val Lys Ala Ala 
                325                 330                 335     


Pro Tyr Trp Leu Asp Glu Pro Lys Asn Leu Ile Leu Ala Pro Gly Glu 
            340                 345                 350         


Asp Gly Arg Leu Val Cys Arg Ala Asn Gly Asn Pro Lys Pro Thr Val 
        355                 360                 365             


Gln Trp Met Val Asn Gly Glu Pro Leu Gln Ser Ala Pro Pro Asn Pro 
    370                 375                 380                 


Asn Arg Glu Val Ala Gly Asp Thr Ile Ile Phe Arg Asp Thr Gln Ile 
385                 390                 395                 400 


Ser Ser Arg Ala Val Tyr Gln Cys Asn Thr Ser Asn Glu His Gly Tyr 
                405                 410                 415     


Leu Leu Ala Asn Ala Phe Val Ser Val Leu Asp Val Pro Pro Arg Met 
            420                 425                 430         


Leu Ser Pro Arg Asn Gln Leu Ile Arg Val Ile Leu Tyr Asn Arg Thr 
        435                 440                 445             


Arg Leu Asp Cys Pro Phe Phe Gly Ser Pro Ile Pro Thr Leu Arg Trp 
    450                 455                 460                 


Phe Lys Asn Gly Gln Gly Ser Asn Leu Asp Gly Gly Asn Tyr His Val 
465                 470                 475                 480 


Tyr Glu Asn Gly Ser Leu Glu Ile Lys Met Ile Arg Lys Glu Asp Gln 
                485                 490                 495     


Gly Ile Tyr Thr Cys Val Ala Thr Asn Ile Leu Gly Lys Ala Glu Asn 
            500                 505                 510         


Gln Val Arg Leu Glu Val Lys Asp Pro Thr Arg Ile Tyr Arg Met Pro 
        515                 520                 525             


Glu Asp Gln Val Ala Arg Arg Gly Thr Thr Val Gln Leu Glu Cys Arg 
    530                 535                 540                 


Val Lys His Asp Pro Ser Leu Lys Leu Thr Val Ser Trp Leu Lys Asp 
545                 550                 555                 560 


Asp Glu Pro Leu Tyr Ile Gly Asn Arg Met Lys Lys Glu Asp Asp Ser 
                565                 570                 575     


Leu Thr Ile Phe Gly Val Ala Glu Arg Asp Gln Gly Ser Tyr Thr Cys 
            580                 585                 590         


Val Ala Ser Thr Glu Leu Asp Gln Asp Leu Ala Lys Ala Tyr Leu Thr 
        595                 600                 605             


Val Leu Gly Asn Cys Pro Cys Ser Pro Trp His 
    610                 615                 


<210>  3129
<211>  1046
<212>  PRT
<213>  homo sapiens

<400>  3129

Met Ala Ser Ser Val Gly Asn Val Ala Asp Ser Thr Glu Pro Thr Lys 
1               5                   10                  15      


Arg Met Leu Ser Phe Gln Gly Leu Ala Glu Leu Ala His Arg Glu Tyr 
            20                  25                  30          


Gln Ala Gly Asp Phe Glu Ala Ala Glu Arg His Cys Met Gln Leu Trp 
        35                  40                  45              


Arg Gln Glu Pro Asp Asn Thr Gly Val Leu Leu Leu Leu Ser Ser Ile 
    50                  55                  60                  


His Phe Gln Cys Arg Arg Leu Asp Arg Ser Ala His Phe Ser Thr Leu 
65                  70                  75                  80  


Ala Ile Lys Gln Asn Pro Leu Leu Ala Glu Ala Tyr Ser Asn Leu Gly 
                85                  90                  95      


Asn Val Tyr Lys Glu Arg Gly Gln Leu Gln Glu Ala Ile Glu His Tyr 
            100                 105                 110         


Arg His Ala Leu Arg Leu Lys Pro Asp Phe Ile Asp Gly Tyr Ile Asn 
        115                 120                 125             


Leu Ala Ala Ala Leu Val Ala Ala Gly Asp Met Glu Gly Ala Val Gln 
    130                 135                 140                 


Ala Tyr Val Ser Ala Leu Gln Tyr Asn Pro Asp Leu Tyr Cys Val Arg 
145                 150                 155                 160 


Ser Asp Leu Gly Asn Leu Leu Lys Ala Leu Gly Arg Leu Glu Glu Ala 
                165                 170                 175     


Lys Ala Cys Tyr Leu Lys Ala Ile Glu Thr Gln Pro Asn Phe Ala Val 
            180                 185                 190         


Ala Trp Ser Asn Leu Gly Cys Val Phe Asn Ala Gln Gly Glu Ile Trp 
        195                 200                 205             


Leu Ala Ile His His Phe Glu Lys Ala Val Thr Leu Asp Pro Asn Phe 
    210                 215                 220                 


Leu Asp Ala Tyr Ile Asn Leu Gly Asn Val Leu Lys Glu Ala Arg Ile 
225                 230                 235                 240 


Phe Asp Arg Ala Val Ala Ala Tyr Leu Arg Ala Leu Ser Leu Ser Pro 
                245                 250                 255     


Asn His Ala Val Val His Gly Asn Leu Ala Cys Val Tyr Tyr Glu Gln 
            260                 265                 270         


Gly Leu Ile Asp Leu Ala Ile Asp Thr Tyr Arg Arg Ala Ile Glu Leu 
        275                 280                 285             


Gln Pro His Phe Pro Asp Ala Tyr Cys Asn Leu Ala Asn Ala Leu Lys 
    290                 295                 300                 


Glu Lys Gly Ser Val Ala Glu Ala Glu Asp Cys Tyr Asn Thr Ala Leu 
305                 310                 315                 320 


Arg Leu Cys Pro Thr His Ala Asp Ser Leu Asn Asn Leu Ala Asn Ile 
                325                 330                 335     


Lys Arg Glu Gln Gly Asn Ile Glu Glu Ala Val Arg Leu Tyr Arg Lys 
            340                 345                 350         


Ala Leu Glu Val Phe Pro Glu Phe Ala Ala Ala His Ser Asn Leu Ala 
        355                 360                 365             


Ser Val Leu Gln Gln Gln Gly Lys Leu Gln Glu Ala Leu Met His Tyr 
    370                 375                 380                 


Lys Glu Ala Ile Arg Ile Ser Pro Thr Phe Ala Asp Ala Tyr Ser Asn 
385                 390                 395                 400 


Met Gly Asn Thr Leu Lys Glu Met Gln Asp Val Gln Gly Ala Leu Gln 
                405                 410                 415     


Cys Tyr Thr Arg Ala Ile Gln Ile Asn Pro Ala Phe Ala Asp Ala His 
            420                 425                 430         


Ser Asn Leu Ala Ser Ile His Lys Asp Ser Gly Asn Ile Pro Glu Ala 
        435                 440                 445             


Ile Ala Ser Tyr Arg Thr Ala Leu Lys Leu Lys Pro Asp Phe Pro Asp 
    450                 455                 460                 


Ala Tyr Cys Asn Leu Ala His Cys Leu Gln Ile Val Cys Asp Trp Thr 
465                 470                 475                 480 


Asp Tyr Asp Glu Arg Met Lys Lys Leu Val Ser Ile Val Ala Asp Gln 
                485                 490                 495     


Leu Glu Lys Asn Arg Leu Pro Ser Val His Pro His His Ser Met Leu 
            500                 505                 510         


Tyr Pro Leu Ser His Gly Phe Arg Lys Ala Ile Ala Glu Arg His Gly 
        515                 520                 525             


Asn Leu Cys Leu Asp Lys Ile Asn Val Leu His Lys Pro Pro Tyr Glu 
    530                 535                 540                 


His Pro Lys Asp Leu Lys Leu Ser Asp Gly Arg Leu Arg Val Gly Tyr 
545                 550                 555                 560 


Val Ser Ser Asp Phe Gly Asn His Pro Thr Ser His Leu Met Gln Ser 
                565                 570                 575     


Ile Pro Gly Met His Asn Pro Asp Lys Phe Glu Val Phe Cys Tyr Ala 
            580                 585                 590         


Leu Ser Pro Asp Asp Gly Thr Asn Phe Arg Val Lys Val Met Ala Glu 
        595                 600                 605             


Ala Asn His Phe Ile Asp Leu Ser Gln Ile Pro Cys Asn Gly Lys Ala 
    610                 615                 620                 


Ala Asp Arg Ile His Gln Asp Gly Ile His Ile Leu Val Asn Met Asn 
625                 630                 635                 640 


Gly Tyr Thr Lys Gly Ala Arg Asn Glu Leu Phe Ala Leu Arg Pro Ala 
                645                 650                 655     


Pro Ile Gln Ala Met Trp Leu Gly Tyr Pro Gly Thr Ser Gly Ala Leu 
            660                 665                 670         


Phe Met Asp Tyr Ile Ile Thr Asp Gln Glu Thr Ser Pro Ala Glu Val 
        675                 680                 685             


Ala Glu Gln Tyr Ser Glu Lys Leu Ala Tyr Met Pro His Thr Phe Phe 
    690                 695                 700                 


Ile Gly Asp His Ala Asn Met Phe Pro His Leu Lys Lys Lys Ala Val 
705                 710                 715                 720 


Ile Asp Phe Lys Ser Asn Gly His Ile Tyr Asp Asn Arg Ile Val Leu 
                725                 730                 735     


Asn Gly Ile Asp Leu Lys Ala Phe Leu Asp Ser Leu Pro Asp Val Lys 
            740                 745                 750         


Ile Val Lys Met Lys Cys Pro Asp Gly Gly Asp Asn Ala Asp Ser Ser 
        755                 760                 765             


Asn Thr Ala Leu Asn Met Pro Val Ile Pro Met Asn Thr Ile Ala Glu 
    770                 775                 780                 


Ala Val Ile Glu Met Ile Asn Arg Gly Gln Ile Gln Ile Thr Ile Asn 
785                 790                 795                 800 


Gly Phe Ser Ile Ser Asn Gly Leu Ala Thr Thr Gln Ile Asn Asn Lys 
                805                 810                 815     


Ala Ala Thr Gly Glu Glu Val Pro Arg Thr Ile Ile Val Thr Thr Arg 
            820                 825                 830         


Ser Gln Tyr Gly Leu Pro Glu Asp Ala Ile Val Tyr Cys Asn Phe Asn 
        835                 840                 845             


Gln Leu Tyr Lys Ile Asp Pro Ser Thr Leu Gln Met Trp Ala Asn Ile 
    850                 855                 860                 


Leu Lys Arg Val Pro Asn Ser Val Leu Trp Leu Leu Arg Phe Pro Ala 
865                 870                 875                 880 


Val Gly Glu Pro Asn Ile Gln Gln Tyr Ala Gln Asn Met Gly Leu Pro 
                885                 890                 895     


Gln Asn Arg Ile Ile Phe Ser Pro Val Ala Pro Lys Glu Glu His Val 
            900                 905                 910         


Arg Arg Gly Gln Leu Ala Asp Val Cys Leu Asp Thr Pro Leu Cys Asn 
        915                 920                 925             


Gly His Thr Thr Gly Met Asp Val Leu Trp Ala Gly Thr Pro Met Val 
    930                 935                 940                 


Thr Met Pro Gly Glu Thr Leu Ala Ser Arg Val Ala Ala Ser Gln Leu 
945                 950                 955                 960 


Thr Cys Leu Gly Cys Leu Glu Leu Ile Ala Lys Asn Arg Gln Glu Tyr 
                965                 970                 975     


Glu Asp Ile Ala Val Lys Leu Gly Thr Asp Leu Glu Tyr Leu Lys Lys 
            980                 985                 990         


Val Arg Gly Lys Val Trp Lys Gln  Arg Ile Ser Ser Pro  Leu Phe Asn 
        995                 1000                 1005             


Thr Lys  Gln Tyr Thr Met Glu  Leu Glu Arg Leu Tyr  Leu Gln Met 
    1010                 1015                 1020             


Trp Glu  His Tyr Ala Ala Gly  Asn Lys Pro Asp His  Met Ile Lys 
    1025                 1030                 1035             


Pro Val  Glu Val Thr Glu Ser  Ala 
    1040                 1045     


<210>  3130
<211>  617
<212>  PRT
<213>  homo sapiens

<400>  3130

Met Ala Glu Ala Lys Thr His Trp Leu Gly Ala Ala Leu Ser Leu Ile 
1               5                   10                  15      


Pro Leu Ile Phe Leu Ile Ser Gly Ala Glu Ala Ala Ser Phe Gln Arg 
            20                  25                  30          


Asn Gln Leu Leu Gln Lys Glu Pro Asp Leu Arg Leu Glu Asn Val Gln 
        35                  40                  45              


Lys Phe Pro Ser Pro Glu Met Ile Arg Ala Leu Glu Tyr Ile Glu Asn 
    50                  55                  60                  


Leu Arg Gln Gln Ala His Lys Glu Glu Ser Ser Pro Asp Tyr Asn Pro 
65                  70                  75                  80  


Tyr Gln Gly Val Ser Val Pro Leu Gln Gln Lys Glu Asn Gly Asp Glu 
                85                  90                  95      


Ser His Leu Pro Glu Arg Asp Ser Leu Ser Glu Glu Asp Trp Met Arg 
            100                 105                 110         


Ile Ile Leu Glu Ala Leu Arg Gln Ala Glu Asn Glu Pro Gln Ser Ala 
        115                 120                 125             


Pro Lys Glu Asn Lys Pro Tyr Ala Leu Asn Ser Glu Lys Asn Phe Pro 
    130                 135                 140                 


Met Asp Met Ser Asp Asp Tyr Glu Thr Gln Gln Trp Pro Glu Arg Lys 
145                 150                 155                 160 


Leu Lys His Met Gln Phe Pro Pro Met Tyr Glu Glu Asn Ser Arg Asp 
                165                 170                 175     


Asn Pro Phe Lys Arg Thr Asn Glu Ile Val Glu Glu Gln Tyr Thr Pro 
            180                 185                 190         


Gln Ser Leu Ala Thr Leu Glu Ser Val Phe Gln Glu Leu Gly Lys Leu 
        195                 200                 205             


Thr Gly Pro Asn Asn Gln Lys Arg Glu Arg Met Asp Glu Glu Gln Lys 
    210                 215                 220                 


Leu Tyr Thr Asp Asp Glu Asp Asp Ile Tyr Lys Ala Asn Asn Ile Ala 
225                 230                 235                 240 


Tyr Glu Asp Val Val Gly Gly Glu Asp Trp Asn Pro Val Glu Glu Lys 
                245                 250                 255     


Ile Glu Ser Gln Thr Gln Glu Glu Val Arg Asp Ser Lys Glu Asn Ile 
            260                 265                 270         


Glu Lys Asn Glu Gln Ile Asn Asp Glu Met Lys Arg Ser Gly Gln Leu 
        275                 280                 285             


Gly Ile Gln Glu Glu Asp Leu Arg Lys Glu Ser Lys Asp Gln Leu Ser 
    290                 295                 300                 


Asp Asp Val Ser Lys Val Ile Ala Tyr Leu Lys Arg Leu Val Asn Ala 
305                 310                 315                 320 


Ala Gly Ser Gly Arg Leu Gln Asn Gly Gln Asn Gly Glu Arg Ala Thr 
                325                 330                 335     


Arg Leu Phe Glu Lys Pro Leu Asp Ser Gln Ser Ile Tyr Gln Leu Ile 
            340                 345                 350         


Glu Ile Ser Arg Asn Leu Gln Ile Pro Pro Glu Asp Leu Ile Glu Met 
        355                 360                 365             


Leu Lys Thr Gly Glu Lys Pro Asn Gly Ser Val Glu Pro Glu Arg Glu 
    370                 375                 380                 


Leu Asp Leu Pro Val Asp Leu Asp Asp Ile Ser Glu Ala Asp Leu Asp 
385                 390                 395                 400 


His Pro Asp Leu Phe Gln Asn Arg Met Leu Ser Lys Ser Gly Tyr Pro 
                405                 410                 415     


Lys Thr Pro Gly Arg Ala Gly Thr Glu Ala Leu Pro Asp Gly Leu Ser 
            420                 425                 430         


Val Glu Asp Ile Leu Asn Leu Leu Gly Met Glu Ser Ala Ala Asn Gln 
        435                 440                 445             


Lys Thr Ser Tyr Phe Pro Asn Pro Tyr Asn Gln Glu Lys Val Leu Pro 
    450                 455                 460                 


Arg Leu Pro Tyr Gly Ala Gly Arg Ser Arg Ser Asn Gln Leu Pro Lys 
465                 470                 475                 480 


Ala Ala Trp Ile Pro His Val Glu Asn Arg Gln Met Ala Tyr Glu Asn 
                485                 490                 495     


Leu Asn Asp Lys Asp Gln Glu Leu Gly Glu Tyr Leu Ala Arg Met Leu 
            500                 505                 510         


Val Lys Tyr Pro Glu Ile Ile Asn Ser Asn Gln Val Lys Arg Val Pro 
        515                 520                 525             


Gly Gln Gly Ser Ser Glu Asp Asp Leu Gln Glu Glu Glu Gln Ile Glu 
    530                 535                 540                 


Gln Ala Ile Lys Glu His Leu Asn Gln Gly Ser Ser Gln Glu Thr Asp 
545                 550                 555                 560 


Lys Leu Ala Pro Val Ser Lys Arg Phe Pro Val Gly Pro Pro Lys Asn 
                565                 570                 575     


Asp Asp Thr Pro Asn Arg Gln Tyr Trp Asp Glu Asp Leu Leu Met Lys 
            580                 585                 590         


Val Leu Glu Tyr Leu Asn Gln Glu Lys Ala Glu Lys Gly Arg Glu His 
        595                 600                 605             


Ile Ala Lys Arg Ala Met Glu Asn Met 
    610                 615         


<210>  3131
<211>  535
<212>  PRT
<213>  homo sapiens

<400>  3131

Met Glu Glu Gly Ala Arg His Arg Asn Asn Thr Glu Lys Lys His Pro 
1               5                   10                  15      


Gly Gly Gly Glu Ser Asp Ala Ser Pro Glu Ala Gly Ser Gly Gly Gly 
            20                  25                  30          


Gly Val Ala Leu Lys Lys Glu Ile Gly Leu Val Ser Ala Cys Gly Ile 
        35                  40                  45              


Ile Val Gly Asn Ile Ile Gly Ser Gly Ile Phe Val Ser Pro Lys Gly 
    50                  55                  60                  


Val Leu Glu Asn Ala Gly Ser Val Gly Leu Ala Leu Ile Val Trp Ile 
65                  70                  75                  80  


Val Thr Gly Phe Ile Thr Val Val Gly Ala Leu Cys Tyr Ala Glu Leu 
                85                  90                  95      


Gly Val Thr Ile Pro Lys Ser Gly Gly Asp Tyr Ser Tyr Val Lys Asp 
            100                 105                 110         


Ile Phe Gly Gly Leu Ala Gly Phe Leu Arg Leu Trp Ile Ala Val Leu 
        115                 120                 125             


Val Ile Tyr Pro Thr Asn Gln Ala Val Ile Ala Leu Thr Phe Ser Asn 
    130                 135                 140                 


Tyr Val Leu Gln Pro Leu Phe Pro Thr Cys Phe Pro Pro Glu Ser Gly 
145                 150                 155                 160 


Leu Arg Leu Leu Ala Ala Ile Cys Leu Leu Leu Leu Thr Trp Val Asn 
                165                 170                 175     


Cys Ser Ser Val Arg Trp Ala Thr Arg Val Gln Asp Ile Phe Thr Ala 
            180                 185                 190         


Gly Lys Leu Leu Ala Leu Ala Leu Ile Ile Ile Met Gly Ile Val Gln 
        195                 200                 205             


Ile Cys Lys Gly Glu Tyr Phe Trp Leu Glu Pro Lys Asn Ala Phe Glu 
    210                 215                 220                 


Asn Phe Gln Glu Pro Asp Ile Gly Leu Val Ala Leu Ala Phe Leu Gln 
225                 230                 235                 240 


Gly Ser Phe Ala Tyr Gly Gly Trp Asn Phe Leu Asn Tyr Val Thr Glu 
                245                 250                 255     


Glu Leu Val Asp Pro Tyr Lys Asn Leu Pro Arg Ala Ile Phe Ile Ser 
            260                 265                 270         


Ile Pro Leu Val Thr Phe Val Tyr Val Phe Ala Asn Val Ala Tyr Val 
        275                 280                 285             


Thr Ala Met Ser Pro Gln Glu Leu Leu Ala Ser Asn Ala Val Ala Val 
    290                 295                 300                 


Thr Phe Gly Glu Lys Leu Leu Gly Val Met Ala Trp Ile Met Pro Ile 
305                 310                 315                 320 


Ser Val Ala Leu Ser Thr Phe Gly Gly Val Asn Gly Ser Leu Phe Thr 
                325                 330                 335     


Ser Ser Arg Leu Phe Phe Ala Gly Ala Arg Glu Gly His Leu Pro Ser 
            340                 345                 350         


Val Leu Ala Met Ile His Val Lys Arg Cys Thr Pro Ile Pro Ala Leu 
        355                 360                 365             


Leu Phe Thr Cys Ile Ser Thr Leu Leu Met Leu Val Thr Ser Asp Met 
    370                 375                 380                 


Tyr Thr Leu Ile Asn Tyr Val Gly Phe Ile Asn Tyr Leu Phe Tyr Gly 
385                 390                 395                 400 


Val Thr Val Ala Gly Gln Ile Val Leu Arg Trp Lys Lys Pro Asp Ile 
                405                 410                 415     


Pro Arg Pro Ile Lys Ile Asn Leu Leu Phe Pro Ile Ile Tyr Leu Leu 
            420                 425                 430         


Phe Trp Ala Phe Leu Leu Val Phe Ser Leu Trp Ser Glu Pro Val Val 
        435                 440                 445             


Cys Gly Ile Gly Leu Ala Ile Met Leu Thr Gly Val Pro Val Tyr Phe 
    450                 455                 460                 


Leu Gly Val Tyr Trp Gln His Lys Pro Lys Cys Phe Ser Asp Phe Ile 
465                 470                 475                 480 


Glu Leu Leu Thr Leu Val Ser Gln Lys Met Cys Val Val Val Tyr Pro 
                485                 490                 495     


Glu Val Glu Arg Gly Ser Gly Thr Glu Glu Ala Asn Glu Asp Met Glu 
            500                 505                 510         


Glu Gln Gln Gln Pro Met Tyr Gln Pro Thr Pro Thr Lys Asp Lys Asp 
        515                 520                 525             


Val Ala Gly Gln Pro Gln Pro 
    530                 535 


<210>  3132
<211>  1951
<212>  PRT
<213>  homo sapiens

<400>  3132

Met Ala Gln Ala Leu Leu Val Pro Pro Gly Pro Glu Ser Phe Arg Leu 
1               5                   10                  15      


Phe Thr Arg Glu Ser Leu Ala Ala Ile Glu Lys Arg Ala Ala Glu Glu 
            20                  25                  30          


Lys Ala Lys Lys Pro Lys Lys Glu Gln Asp Asn Asp Asp Glu Asn Lys 
        35                  40                  45              


Pro Lys Pro Asn Ser Asp Leu Glu Ala Gly Lys Asn Leu Pro Phe Ile 
    50                  55                  60                  


Tyr Gly Asp Ile Pro Pro Glu Met Val Ser Glu Pro Leu Glu Asp Leu 
65                  70                  75                  80  


Asp Pro Tyr Tyr Ile Asn Lys Lys Thr Phe Ile Val Met Asn Lys Gly 
                85                  90                  95      


Lys Ala Ile Phe Arg Phe Ser Ala Thr Ser Ala Leu Tyr Ile Leu Thr 
            100                 105                 110         


Pro Leu Asn Pro Val Arg Lys Ile Ala Ile Lys Ile Leu Val His Ser 
        115                 120                 125             


Leu Phe Ser Met Leu Ile Met Cys Thr Ile Leu Thr Asn Cys Val Phe 
    130                 135                 140                 


Met Thr Leu Ser Asn Pro Pro Asp Trp Thr Lys Asn Val Glu Tyr Thr 
145                 150                 155                 160 


Phe Thr Gly Ile Tyr Thr Phe Glu Ser Leu Ile Lys Ile Leu Ala Arg 
                165                 170                 175     


Gly Phe Cys Leu Glu Asp Phe Thr Phe Leu Arg Asp Pro Trp Asn Trp 
            180                 185                 190         


Leu Asp Phe Ser Val Ile Val Met Ala Tyr Val Thr Glu Phe Val Asp 
        195                 200                 205             


Leu Gly Asn Val Ser Ala Leu Arg Thr Phe Arg Val Leu Arg Ala Leu 
    210                 215                 220                 


Lys Thr Ile Ser Val Ile Pro Gly Leu Lys Thr Ile Val Gly Ala Leu 
225                 230                 235                 240 


Ile Gln Ser Val Lys Lys Leu Ser Asp Val Met Ile Leu Thr Val Phe 
                245                 250                 255     


Cys Leu Ser Val Phe Ala Leu Ile Gly Leu Gln Leu Phe Met Gly Asn 
            260                 265                 270         


Leu Arg Asn Lys Cys Leu Gln Trp Pro Pro Ser Asp Ser Ala Phe Glu 
        275                 280                 285             


Thr Asn Thr Thr Ser Tyr Phe Asn Gly Thr Met Asp Ser Asn Gly Thr 
    290                 295                 300                 


Phe Val Asn Val Thr Met Ser Thr Phe Asn Trp Lys Asp Tyr Ile Gly 
305                 310                 315                 320 


Asp Asp Ser His Phe Tyr Val Leu Asp Gly Gln Lys Asp Pro Leu Leu 
                325                 330                 335     


Cys Gly Asn Gly Ser Asp Ala Gly Gln Cys Pro Glu Gly Tyr Ile Cys 
            340                 345                 350         


Val Lys Ala Gly Arg Asn Pro Asn Tyr Gly Tyr Thr Ser Phe Asp Thr 
        355                 360                 365             


Phe Ser Trp Ala Phe Leu Ser Leu Phe Arg Leu Met Thr Gln Asp Tyr 
    370                 375                 380                 


Trp Glu Asn Leu Tyr Gln Leu Thr Leu Arg Ala Ala Gly Lys Thr Tyr 
385                 390                 395                 400 


Met Ile Phe Phe Val Leu Val Ile Phe Leu Gly Ser Phe Tyr Leu Val 
                405                 410                 415     


Asn Leu Ile Leu Ala Val Val Ala Met Ala Tyr Glu Glu Gln Asn Gln 
            420                 425                 430         


Ala Thr Leu Glu Glu Ala Glu Gln Lys Glu Ala Glu Phe Gln Gln Met 
        435                 440                 445             


Leu Glu Gln Leu Lys Lys Gln Gln Glu Glu Ala Gln Ala Val Ala Ala 
    450                 455                 460                 


Ala Ser Ala Ala Ser Arg Asp Phe Ser Gly Ile Gly Gly Leu Gly Glu 
465                 470                 475                 480 


Leu Leu Glu Ser Ser Ser Glu Ala Ser Lys Leu Ser Ser Lys Ser Ala 
                485                 490                 495     


Lys Glu Trp Arg Asn Arg Arg Lys Lys Arg Arg Gln Arg Glu His Leu 
            500                 505                 510         


Glu Gly Asn Asn Lys Gly Glu Arg Asp Ser Phe Pro Lys Ser Glu Ser 
        515                 520                 525             


Glu Asp Ser Val Lys Arg Ser Ser Phe Leu Phe Ser Met Asp Gly Asn 
    530                 535                 540                 


Arg Leu Thr Ser Asp Lys Lys Phe Cys Ser Pro His Gln Ser Leu Leu 
545                 550                 555                 560 


Ser Ile Arg Gly Ser Leu Phe Ser Pro Arg Arg Asn Ser Lys Thr Ser 
                565                 570                 575     


Ile Phe Ser Phe Arg Gly Arg Ala Lys Asp Val Gly Ser Glu Asn Asp 
            580                 585                 590         


Phe Ala Asp Asp Glu His Ser Thr Phe Glu Asp Ser Glu Ser Arg Arg 
        595                 600                 605             


Asp Ser Leu Phe Val Pro His Arg His Gly Glu Arg Arg Asn Ser Asn 
    610                 615                 620                 


Gly Thr Thr Thr Glu Thr Glu Val Arg Lys Arg Arg Leu Ser Ser Tyr 
625                 630                 635                 640 


Gln Ile Ser Met Glu Met Leu Glu Asp Ser Ser Gly Arg Gln Arg Ala 
                645                 650                 655     


Val Ser Ile Ala Ser Ile Leu Thr Asn Thr Met Glu Glu Leu Glu Glu 
            660                 665                 670         


Ser Arg Gln Lys Cys Pro Pro Cys Trp Tyr Arg Phe Ala Asn Val Phe 
        675                 680                 685             


Leu Ile Trp Asp Cys Cys Asp Ala Trp Leu Lys Val Lys His Leu Val 
    690                 695                 700                 


Asn Leu Ile Val Met Asp Pro Phe Val Asp Leu Ala Ile Thr Ile Cys 
705                 710                 715                 720 


Ile Val Leu Asn Thr Leu Phe Met Ala Met Glu His Tyr Pro Met Thr 
                725                 730                 735     


Glu Gln Phe Ser Ser Val Leu Thr Val Gly Asn Leu Val Phe Thr Gly 
            740                 745                 750         


Ile Phe Thr Ala Glu Met Val Leu Lys Ile Ile Ala Met Asp Pro Tyr 
        755                 760                 765             


Tyr Tyr Phe Gln Glu Gly Trp Asn Ile Phe Asp Gly Ile Ile Val Ser 
    770                 775                 780                 


Leu Ser Leu Met Glu Leu Gly Leu Ser Asn Val Glu Gly Leu Ser Val 
785                 790                 795                 800 


Leu Arg Ser Phe Arg Leu Leu Arg Val Phe Lys Leu Ala Lys Ser Trp 
                805                 810                 815     


Pro Thr Leu Asn Met Leu Ile Lys Ile Ile Gly Asn Ser Val Gly Ala 
            820                 825                 830         


Leu Gly Asn Leu Thr Leu Val Leu Ala Ile Ile Val Phe Ile Phe Ala 
        835                 840                 845             


Val Val Gly Met Gln Leu Phe Gly Lys Ser Tyr Lys Glu Cys Val Cys 
    850                 855                 860                 


Lys Ile Asn Asp Asp Cys Thr Leu Pro Arg Trp His Met Asn Asp Phe 
865                 870                 875                 880 


Phe His Ser Phe Leu Ile Val Phe Arg Val Leu Cys Gly Glu Trp Ile 
                885                 890                 895     


Glu Thr Met Trp Asp Cys Met Glu Val Ala Gly Gln Thr Met Cys Leu 
            900                 905                 910         


Ile Val Phe Met Leu Val Met Val Ile Gly Asn Leu Val Val Leu Asn 
        915                 920                 925             


Leu Phe Leu Ala Leu Leu Leu Ser Ser Phe Ser Ser Asp Asn Leu Ala 
    930                 935                 940                 


Ala Thr Asp Asp Asp Asn Glu Met Asn Asn Leu Gln Ile Ala Val Gly 
945                 950                 955                 960 


Arg Met Gln Lys Gly Ile Asp Tyr Val Lys Asn Lys Met Arg Glu Cys 
                965                 970                 975     


Phe Gln Lys Ala Phe Phe Arg Lys Pro Lys Val Ile Glu Ile His Glu 
            980                 985                 990         


Gly Asn Lys Ile Asp Ser Cys Met  Ser Asn Asn Thr Gly  Ile Glu Ile 
        995                 1000                 1005             


Ser Lys  Glu Leu Asn Tyr Leu  Arg Asp Gly Asn Gly  Thr Thr Ser 
    1010                 1015                 1020             


Gly Val  Gly Thr Gly Ser Ser  Val Glu Lys Tyr Val  Ile Asp Glu 
    1025                 1030                 1035             


Asn Asp  Tyr Met Ser Phe Ile  Asn Asn Pro Ser Leu  Thr Val Thr 
    1040                 1045                 1050             


Val Pro  Ile Ala Val Gly Glu  Ser Asp Phe Glu Asn  Leu Asn Thr 
    1055                 1060                 1065             


Glu Glu  Phe Ser Ser Glu Ser  Glu Leu Glu Glu Ser  Lys Glu Lys 
    1070                 1075                 1080             


Leu Asn  Ala Thr Ser Ser Ser  Glu Gly Ser Thr Val  Asp Val Val 
    1085                 1090                 1095             


Leu Pro  Arg Glu Gly Glu Gln  Ala Glu Thr Glu Pro  Glu Glu Asp 
    1100                 1105                 1110             


Leu Lys  Pro Glu Ala Cys Phe  Thr Glu Gly Cys Ile  Lys Lys Phe 
    1115                 1120                 1125             


Pro Phe  Cys Gln Val Ser Thr  Glu Glu Gly Lys Gly  Lys Ile Trp 
    1130                 1135                 1140             


Trp Asn  Leu Arg Lys Thr Cys  Tyr Ser Ile Val Glu  His Asn Trp 
    1145                 1150                 1155             


Phe Glu  Thr Phe Ile Val Phe  Met Ile Leu Leu Ser  Ser Gly Ala 
    1160                 1165                 1170             


Leu Ala  Phe Glu Asp Ile Tyr  Ile Glu Gln Arg Lys  Thr Ile Lys 
    1175                 1180                 1185             


Thr Met  Leu Glu Tyr Ala Asp  Lys Val Phe Thr Tyr  Ile Phe Ile 
    1190                 1195                 1200             


Leu Glu  Met Leu Leu Lys Trp  Val Ala Tyr Gly Phe  Gln Thr Tyr 
    1205                 1210                 1215             


Phe Thr  Asn Ala Trp Cys Trp  Leu Asp Phe Leu Ile  Val Asp Val 
    1220                 1225                 1230             


Ser Leu  Val Ser Leu Val Ala  Asn Ala Leu Gly Tyr  Ser Glu Leu 
    1235                 1240                 1245             


Gly Ala  Ile Lys Ser Leu Arg  Thr Leu Arg Ala Leu  Arg Pro Leu 
    1250                 1255                 1260             


Arg Ala  Leu Ser Arg Phe Glu  Gly Met Arg Val Val  Val Asn Ala 
    1265                 1270                 1275             


Leu Val  Gly Ala Ile Pro Ser  Ile Met Asn Val Leu  Leu Val Cys 
    1280                 1285                 1290             


Leu Ile  Phe Trp Leu Ile Phe  Ser Ile Met Gly Val  Asn Leu Phe 
    1295                 1300                 1305             


Ala Gly  Lys Phe Tyr His Cys  Val Asn Met Thr Thr  Gly Asn Met 
    1310                 1315                 1320             


Phe Asp  Ile Ser Asp Val Asn  Asn Leu Ser Asp Cys  Gln Ala Leu 
    1325                 1330                 1335             


Gly Lys  Gln Ala Arg Trp Lys  Asn Val Lys Val Asn  Phe Asp Asn 
    1340                 1345                 1350             


Val Gly  Ala Gly Tyr Leu Ala  Leu Leu Gln Val Ala  Thr Phe Lys 
    1355                 1360                 1365             


Gly Trp  Met Asp Ile Met Tyr  Ala Ala Val Asp Ser  Arg Asp Val 
    1370                 1375                 1380             


Lys Leu  Gln Pro Val Tyr Glu  Glu Asn Leu Tyr Met  Tyr Leu Tyr 
    1385                 1390                 1395             


Phe Val  Ile Phe Ile Ile Phe  Gly Ser Phe Phe Thr  Leu Asn Leu 
    1400                 1405                 1410             


Phe Ile  Gly Val Ile Ile Asp  Asn Phe Asn Gln Gln  Lys Lys Lys 
    1415                 1420                 1425             


Phe Gly  Gly Gln Asp Ile Phe  Met Thr Glu Glu Gln  Lys Lys Tyr 
    1430                 1435                 1440             


Tyr Asn  Ala Met Lys Lys Leu  Gly Ser Lys Lys Pro  Gln Lys Pro 
    1445                 1450                 1455             


Ile Pro  Arg Pro Ala Asn Lys  Phe Gln Gly Met Val  Phe Asp Phe 
    1460                 1465                 1470             


Val Thr  Arg Gln Val Phe Asp  Ile Ser Ile Met Ile  Leu Ile Cys 
    1475                 1480                 1485             


Leu Asn  Met Val Thr Met Met  Val Glu Thr Asp Asp  Gln Gly Lys 
    1490                 1495                 1500             


Tyr Met  Thr Leu Val Leu Ser  Arg Ile Asn Leu Val  Phe Ile Val 
    1505                 1510                 1515             


Leu Phe  Thr Gly Glu Phe Val  Leu Lys Leu Val Ser  Leu Arg His 
    1520                 1525                 1530             


Tyr Tyr  Phe Thr Ile Gly Trp  Asn Ile Phe Asp Phe  Val Val Val 
    1535                 1540                 1545             


Ile Leu  Ser Ile Val Gly Met  Phe Leu Ala Glu Met  Ile Glu Lys 
    1550                 1555                 1560             


Tyr Phe  Val Ser Pro Thr Leu  Phe Arg Val Ile Arg  Leu Ala Arg 
    1565                 1570                 1575             


Ile Gly  Arg Ile Leu Arg Leu  Ile Lys Gly Ala Lys  Gly Ile Arg 
    1580                 1585                 1590             


Thr Leu  Leu Phe Ala Leu Met  Met Ser Leu Pro Ala  Leu Phe Asn 
    1595                 1600                 1605             


Ile Gly  Leu Leu Leu Phe Leu  Val Met Phe Ile Tyr  Ala Ile Phe 
    1610                 1615                 1620             


Gly Met  Ser Asn Phe Ala Tyr  Val Lys Lys Glu Ala  Gly Ile Asp 
    1625                 1630                 1635             


Asp Met  Phe Asn Phe Glu Thr  Phe Gly Asn Ser Met  Ile Cys Leu 
    1640                 1645                 1650             


Phe Gln  Ile Thr Thr Ser Ala  Gly Trp Asp Gly Leu  Leu Ala Pro 
    1655                 1660                 1665             


Ile Leu  Asn Ser Ala Pro Pro  Asp Cys Asp Pro Asp  Thr Ile His 
    1670                 1675                 1680             


Pro Gly  Ser Ser Val Lys Gly  Asp Cys Gly Asn Pro  Ser Val Gly 
    1685                 1690                 1695             


Ile Phe  Phe Phe Val Ser Tyr  Ile Ile Ile Ser Phe  Leu Val Val 
    1700                 1705                 1710             


Val Asn  Met Tyr Ile Ala Val  Ile Leu Glu Asn Phe  Ser Val Ala 
    1715                 1720                 1725             


Thr Glu  Glu Ser Ala Glu Pro  Leu Ser Glu Asp Asp  Phe Glu Met 
    1730                 1735                 1740             


Phe Tyr  Glu Val Trp Glu Lys  Phe Asp Pro Asp Ala  Thr Gln Phe 
    1745                 1750                 1755             


Ile Glu  Phe Ser Lys Leu Ser  Asp Phe Ala Ala Ala  Leu Asp Pro 
    1760                 1765                 1770             


Pro Leu  Leu Ile Ala Lys Pro  Asn Lys Val Gln Leu  Ile Ala Met 
    1775                 1780                 1785             


Asp Leu  Pro Met Val Ser Gly  Asp Arg Ile His Cys  Leu Asp Ile 
    1790                 1795                 1800             


Leu Phe  Ala Phe Thr Lys Arg  Val Leu Gly Glu Ser  Gly Glu Met 
    1805                 1810                 1815             


Asp Ala  Leu Arg Ile Gln Met  Glu Asp Arg Phe Met  Ala Ser Asn 
    1820                 1825                 1830             


Pro Ser  Lys Val Ser Tyr Glu  Pro Ile Thr Thr Thr  Leu Lys Arg 
    1835                 1840                 1845             


Lys Gln  Glu Glu Val Ser Ala  Ala Ile Ile Gln Arg  Asn Phe Arg 
    1850                 1855                 1860             


Cys Tyr  Leu Leu Lys Gln Arg  Leu Lys Asn Ile Ser  Ser Asn Tyr 
    1865                 1870                 1875             


Asn Lys  Glu Ala Ile Lys Gly  Arg Ile Asp Leu Pro  Ile Lys Gln 
    1880                 1885                 1890             


Asp Met  Ile Ile Asp Lys Leu  Asn Gly Asn Ser Thr  Pro Glu Lys 
    1895                 1900                 1905             


Thr Asp  Gly Ser Ser Ser Thr  Thr Ser Pro Pro Ser  Tyr Asp Ser 
    1910                 1915                 1920             


Val Thr  Lys Pro Asp Lys Glu  Lys Phe Glu Lys Asp  Lys Pro Glu 
    1925                 1930                 1935             


Lys Glu  Ser Lys Gly Lys Glu  Val Arg Glu Asn Gln  Lys 
    1940                 1945                 1950     


<210>  3133
<211>  968
<212>  PRT
<213>  homo sapiens

<400>  3133

Met Ala Glu Asp Asp Pro Tyr Leu Gly Arg Pro Glu Gln Met Phe His 
1               5                   10                  15      


Leu Asp Pro Ser Leu Thr His Thr Ile Phe Asn Pro Glu Val Phe Gln 
            20                  25                  30          


Pro Gln Met Ala Leu Pro Thr Asp Gly Pro Tyr Leu Gln Ile Leu Glu 
        35                  40                  45              


Gln Pro Lys Gln Arg Gly Phe Arg Phe Arg Tyr Val Cys Glu Gly Pro 
    50                  55                  60                  


Ser His Gly Gly Leu Pro Gly Ala Ser Ser Glu Lys Asn Lys Lys Ser 
65                  70                  75                  80  


Tyr Pro Gln Val Lys Ile Cys Asn Tyr Val Gly Pro Ala Lys Val Ile 
                85                  90                  95      


Val Gln Leu Val Thr Asn Gly Lys Asn Ile His Leu His Ala His Ser 
            100                 105                 110         


Leu Val Gly Lys His Cys Glu Asp Gly Ile Cys Thr Val Thr Ala Gly 
        115                 120                 125             


Pro Lys Asp Met Val Val Gly Phe Ala Asn Leu Gly Ile Leu His Val 
    130                 135                 140                 


Thr Lys Lys Lys Val Phe Glu Thr Leu Glu Ala Arg Met Thr Glu Ala 
145                 150                 155                 160 


Cys Ile Arg Gly Tyr Asn Pro Gly Leu Leu Val His Pro Asp Leu Ala 
                165                 170                 175     


Tyr Leu Gln Ala Glu Gly Gly Gly Asp Arg Gln Leu Gly Asp Arg Glu 
            180                 185                 190         


Lys Glu Leu Ile Arg Gln Ala Ala Leu Gln Gln Thr Lys Glu Met Asp 
        195                 200                 205             


Leu Ser Val Val Arg Leu Met Phe Thr Ala Phe Leu Pro Asp Ser Thr 
    210                 215                 220                 


Gly Ser Phe Thr Arg Arg Leu Glu Pro Val Val Ser Asp Ala Ile Tyr 
225                 230                 235                 240 


Asp Ser Lys Ala Pro Asn Ala Ser Asn Leu Lys Ile Val Arg Met Asp 
                245                 250                 255     


Arg Thr Ala Gly Cys Val Thr Gly Gly Glu Glu Ile Tyr Leu Leu Cys 
            260                 265                 270         


Asp Lys Val Gln Lys Asp Asp Ile Gln Ile Arg Phe Tyr Glu Glu Glu 
        275                 280                 285             


Glu Asn Gly Gly Val Trp Glu Gly Phe Gly Asp Phe Ser Pro Thr Asp 
    290                 295                 300                 


Val His Arg Gln Phe Ala Ile Val Phe Lys Thr Pro Lys Tyr Lys Asp 
305                 310                 315                 320 


Ile Asn Ile Thr Lys Pro Ala Ser Val Phe Val Gln Leu Arg Arg Lys 
                325                 330                 335     


Ser Asp Leu Glu Thr Ser Glu Pro Lys Pro Phe Leu Tyr Tyr Pro Glu 
            340                 345                 350         


Ile Lys Asp Lys Glu Glu Val Gln Arg Lys Arg Gln Lys Leu Met Pro 
        355                 360                 365             


Asn Phe Ser Asp Ser Phe Gly Gly Gly Ser Gly Ala Gly Ala Gly Gly 
    370                 375                 380                 


Gly Gly Met Phe Gly Ser Gly Gly Gly Gly Gly Gly Thr Gly Ser Thr 
385                 390                 395                 400 


Gly Pro Gly Tyr Ser Phe Pro His Tyr Gly Phe Pro Thr Tyr Gly Gly 
                405                 410                 415     


Ile Thr Phe His Pro Gly Thr Thr Lys Ser Asn Ala Gly Met Lys His 
            420                 425                 430         


Gly Thr Met Asp Thr Glu Ser Lys Lys Asp Pro Glu Gly Cys Asp Lys 
        435                 440                 445             


Ser Asp Asp Lys Asn Thr Val Asn Leu Phe Gly Lys Val Ile Glu Thr 
    450                 455                 460                 


Thr Glu Gln Asp Gln Glu Pro Ser Glu Ala Thr Val Gly Asn Gly Glu 
465                 470                 475                 480 


Val Thr Leu Thr Tyr Ala Thr Gly Thr Lys Glu Glu Ser Ala Gly Val 
                485                 490                 495     


Gln Asp Asn Leu Phe Leu Glu Lys Ala Met Gln Leu Ala Lys Arg His 
            500                 505                 510         


Ala Asn Ala Leu Phe Asp Tyr Ala Val Thr Gly Asp Val Lys Met Leu 
        515                 520                 525             


Leu Ala Val Gln Arg His Leu Thr Ala Val Gln Asp Glu Asn Gly Asp 
    530                 535                 540                 


Ser Val Leu His Leu Ala Ile Ile His Leu His Ser Gln Leu Val Arg 
545                 550                 555                 560 


Asp Leu Leu Glu Val Thr Ser Gly Leu Ile Ser Asp Asp Ile Ile Asn 
                565                 570                 575     


Met Arg Asn Asp Leu Tyr Gln Thr Pro Leu His Leu Ala Val Ile Thr 
            580                 585                 590         


Lys Gln Glu Asp Val Val Glu Asp Leu Leu Arg Ala Gly Ala Asp Leu 
        595                 600                 605             


Ser Leu Leu Asp Arg Leu Gly Asn Ser Val Leu His Leu Ala Ala Lys 
    610                 615                 620                 


Glu Gly His Asp Lys Val Leu Ser Ile Leu Leu Lys His Lys Lys Ala 
625                 630                 635                 640 


Ala Leu Leu Leu Asp His Pro Asn Gly Asp Gly Leu Asn Ala Ile His 
                645                 650                 655     


Leu Ala Met Met Ser Asn Ser Leu Pro Cys Leu Leu Leu Leu Val Ala 
            660                 665                 670         


Ala Gly Ala Asp Val Asn Ala Gln Glu Gln Lys Ser Gly Arg Thr Ala 
        675                 680                 685             


Leu His Leu Ala Val Glu His Asp Asn Ile Ser Leu Ala Gly Cys Leu 
    690                 695                 700                 


Leu Leu Glu Gly Asp Ala His Val Asp Ser Thr Thr Tyr Asp Gly Thr 
705                 710                 715                 720 


Thr Pro Leu His Ile Ala Ala Gly Arg Gly Ser Thr Arg Leu Ala Ala 
                725                 730                 735     


Leu Leu Lys Ala Ala Gly Ala Asp Pro Leu Val Glu Asn Phe Glu Pro 
            740                 745                 750         


Leu Tyr Asp Leu Asp Asp Ser Trp Glu Asn Ala Gly Glu Asp Glu Gly 
        755                 760                 765             


Val Val Pro Gly Thr Thr Pro Leu Asp Met Ala Thr Ser Trp Gln Val 
    770                 775                 780                 


Phe Asp Ile Leu Asn Gly Lys Pro Tyr Glu Pro Glu Phe Thr Ser Asp 
785                 790                 795                 800 


Asp Leu Leu Ala Gln Gly Asp Met Lys Gln Leu Ala Glu Asp Val Lys 
                805                 810                 815     


Leu Gln Leu Tyr Lys Leu Leu Glu Ile Pro Asp Pro Asp Lys Asn Trp 
            820                 825                 830         


Ala Thr Leu Ala Gln Lys Leu Gly Leu Gly Ile Leu Asn Asn Ala Phe 
        835                 840                 845             


Arg Leu Ser Pro Ala Pro Ser Lys Thr Leu Met Asp Asn Tyr Glu Val 
    850                 855                 860                 


Ser Gly Gly Thr Val Arg Glu Leu Val Glu Ala Leu Arg Gln Met Gly 
865                 870                 875                 880 


Tyr Thr Glu Ala Ile Glu Val Ile Gln Ala Ala Ser Ser Pro Val Lys 
                885                 890                 895     


Thr Thr Ser Gln Ala His Ser Leu Pro Leu Ser Pro Ala Ser Thr Arg 
            900                 905                 910         


Gln Gln Ile Asp Glu Leu Arg Asp Ser Asp Ser Val Cys Asp Ser Gly 
        915                 920                 925             


Val Glu Thr Ser Phe Arg Lys Leu Ser Phe Thr Glu Ser Leu Thr Ser 
    930                 935                 940                 


Gly Ala Ser Leu Leu Thr Leu Asn Lys Met Pro His Asp Tyr Gly Gln 
945                 950                 955                 960 


Glu Gly Pro Leu Glu Gly Lys Ile 
                965             


<210>  3134
<211>  1094
<212>  PRT
<213>  homo sapiens

<400>  3134

Met Gly Asn Glu Asn Ser Thr Ser Asp Asn Gln Arg Thr Leu Ser Ala 
1               5                   10                  15      


Gln Thr Pro Arg Ser Ala Gln Pro Pro Gly Asn Ser Gln Asn Ile Lys 
            20                  25                  30          


Arg Lys Gln Gln Asp Thr Pro Gly Ser Pro Asp His Arg Asp Ala Ser 
        35                  40                  45              


Ser Ser Pro Val Ala Asp Asp Ile Ile Gln Pro Ala Ala Pro Ala Asp 
    50                  55                  60                  


Leu Glu Ser Pro Thr Leu Ala Ala Ser Ser Tyr His Gly Asp Val Val 
65                  70                  75                  80  


Gly Gln Val Ser Thr Asp Leu Ile Ala Gln Arg Ser Ser Asp Ser Glu 
                85                  90                  95      


Glu Ala Phe Glu Thr Pro Glu Ser Thr Thr Pro Val Lys Ala Pro Pro 
            100                 105                 110         


Ala Pro Pro Pro Pro Pro Pro Glu Val Ile Pro Glu Pro Glu Val Ser 
        115                 120                 125             


Thr Gln Pro Pro Pro Glu Glu Pro Gly Cys Gly Ser Glu Thr Val Pro 
    130                 135                 140                 


Val Pro Asp Gly Pro Arg Ser Asp Ser Val Glu Gly Ser Pro Phe Arg 
145                 150                 155                 160 


Pro Pro Ser His Ser Phe Ser Ala Val Phe Asp Glu Asp Lys Pro Ile 
                165                 170                 175     


Ala Ser Ser Gly Thr Tyr Asn Leu Asp Phe Asp Asn Ile Glu Leu Val 
            180                 185                 190         


Asp Thr Phe Gln Thr Leu Glu Pro Arg Ala Ser Asp Ala Lys Asn Gln 
        195                 200                 205             


Glu Gly Lys Val Asn Thr Arg Arg Lys Ser Thr Asp Ser Val Pro Ile 
    210                 215                 220                 


Ser Lys Ser Thr Leu Ser Arg Ser Leu Ser Leu Gln Ala Ser Asp Phe 
225                 230                 235                 240 


Asp Gly Ala Ser Ser Ser Gly Asn Pro Glu Ala Val Ala Leu Ala Pro 
                245                 250                 255     


Asp Ala Tyr Ser Thr Gly Ser Ser Ser Ala Ser Ser Thr Leu Lys Arg 
            260                 265                 270         


Thr Lys Lys Pro Arg Pro Pro Ser Leu Lys Lys Lys Gln Thr Thr Lys 
        275                 280                 285             


Lys Pro Thr Glu Thr Pro Pro Val Lys Glu Thr Gln Gln Glu Pro Asp 
    290                 295                 300                 


Glu Glu Ser Leu Val Pro Ser Gly Glu Asn Leu Ala Ser Glu Thr Lys 
305                 310                 315                 320 


Thr Glu Ser Ala Lys Thr Glu Gly Pro Ser Pro Ala Leu Leu Glu Glu 
                325                 330                 335     


Thr Pro Leu Glu Pro Ala Val Gly Pro Lys Ala Ala Cys Pro Leu Asp 
            340                 345                 350         


Ser Glu Ser Ala Glu Gly Val Val Pro Pro Ala Ser Gly Gly Gly Arg 
        355                 360                 365             


Val Gln Asn Ser Pro Pro Val Gly Arg Lys Thr Leu Pro Leu Thr Thr 
    370                 375                 380                 


Ala Pro Glu Ala Gly Glu Val Thr Pro Ser Asp Ser Gly Gly Gln Glu 
385                 390                 395                 400 


Asp Ser Pro Ala Lys Gly Leu Ser Val Arg Leu Glu Phe Asp Tyr Ser 
                405                 410                 415     


Glu Asp Lys Ser Ser Trp Asp Asn Gln Gln Glu Asn Pro Pro Pro Thr 
            420                 425                 430         


Lys Lys Ile Gly Lys Lys Pro Val Ala Lys Met Pro Leu Arg Arg Pro 
        435                 440                 445             


Lys Met Lys Lys Thr Pro Glu Lys Leu Asp Asn Thr Pro Ala Ser Pro 
    450                 455                 460                 


Pro Arg Ser Pro Ala Glu Pro Asn Asp Ile Pro Ile Ala Lys Gly Thr 
465                 470                 475                 480 


Tyr Thr Phe Asp Ile Asp Lys Trp Asp Asp Pro Asn Phe Asn Pro Phe 
                485                 490                 495     


Ser Ser Thr Ser Lys Met Gln Glu Ser Pro Lys Leu Pro Gln Gln Ser 
            500                 505                 510         


Tyr Asn Phe Asp Pro Asp Thr Cys Asp Glu Ser Val Asp Pro Phe Lys 
        515                 520                 525             


Thr Ser Ser Lys Thr Pro Ser Ser Pro Ser Lys Ser Pro Ala Ser Phe 
    530                 535                 540                 


Glu Ile Pro Ala Ser Ala Met Glu Ala Asn Gly Val Asp Gly Asp Gly 
545                 550                 555                 560 


Leu Asn Lys Pro Ala Lys Lys Lys Lys Thr Pro Leu Lys Thr Asp Thr 
                565                 570                 575     


Phe Arg Val Lys Lys Ser Pro Lys Arg Ser Pro Leu Ser Asp Pro Pro 
            580                 585                 590         


Ser Gln Asp Pro Thr Pro Ala Ala Thr Pro Glu Thr Pro Pro Val Ile 
        595                 600                 605             


Ser Ala Val Val His Ala Thr Asp Glu Glu Lys Leu Ala Val Thr Asn 
    610                 615                 620                 


Gln Lys Trp Thr Cys Met Thr Val Asp Leu Glu Ala Asp Lys Gln Asp 
625                 630                 635                 640 


Tyr Pro Gln Pro Ser Asp Leu Ser Thr Phe Val Asn Glu Thr Lys Phe 
                645                 650                 655     


Ser Ser Pro Thr Glu Glu Leu Asp Tyr Arg Asn Ser Tyr Glu Ile Glu 
            660                 665                 670         


Tyr Met Glu Lys Ile Gly Ser Ser Leu Pro Gln Asp Asp Asp Ala Pro 
        675                 680                 685             


Lys Lys Gln Ala Leu Tyr Leu Met Phe Asp Thr Ser Gln Glu Ser Pro 
    690                 695                 700                 


Val Lys Ser Ser Pro Val Arg Met Ser Glu Ser Pro Thr Pro Cys Ser 
705                 710                 715                 720 


Gly Ser Ser Phe Glu Glu Thr Glu Ala Leu Val Asn Thr Ala Ala Lys 
                725                 730                 735     


Asn Gln His Pro Val Pro Arg Gly Leu Ala Pro Asn Gln Glu Ser His 
            740                 745                 750         


Leu Gln Val Pro Glu Lys Ser Ser Gln Lys Glu Leu Glu Ala Met Gly 
        755                 760                 765             


Leu Gly Thr Pro Ser Glu Ala Ile Glu Ile Thr Ala Pro Glu Gly Ser 
    770                 775                 780                 


Phe Ala Ser Ala Asp Ala Leu Leu Ser Arg Leu Ala His Pro Val Ser 
785                 790                 795                 800 


Leu Cys Gly Ala Leu Asp Tyr Leu Glu Pro Asp Leu Ala Glu Lys Asn 
                805                 810                 815     


Pro Pro Leu Phe Ala Gln Lys Leu Gln Glu Glu Leu Glu Phe Ala Ile 
            820                 825                 830         


Met Arg Ile Glu Ala Leu Lys Leu Ala Arg Gln Ile Ala Leu Ala Ser 
        835                 840                 845             


Arg Ser His Gln Asp Ala Lys Arg Glu Ala Ala His Pro Thr Asp Val 
    850                 855                 860                 


Ser Ile Ser Lys Thr Ala Leu Tyr Ser Arg Ile Gly Thr Ala Glu Val 
865                 870                 875                 880 


Glu Lys Pro Ala Gly Leu Leu Phe Gln Gln Pro Asp Leu Asp Ser Ala 
                885                 890                 895     


Leu Gln Ile Ala Arg Ala Glu Ile Ile Thr Lys Glu Arg Glu Val Ser 
            900                 905                 910         


Glu Trp Lys Asp Lys Tyr Glu Glu Ser Arg Arg Glu Val Met Glu Met 
        915                 920                 925             


Arg Lys Ile Val Ala Glu Tyr Glu Lys Thr Ile Ala Gln Met Ile Glu 
    930                 935                 940                 


Asp Glu Gln Arg Glu Lys Ser Val Ser His Gln Thr Val Gln Gln Leu 
945                 950                 955                 960 


Val Leu Glu Lys Glu Gln Ala Leu Ala Asp Leu Asn Ser Val Glu Lys 
                965                 970                 975     


Ser Leu Ala Asp Leu Phe Arg Arg Tyr Glu Lys Met Lys Glu Val Leu 
            980                 985                 990         


Glu Gly Phe Arg Lys Asn Glu Glu  Val Leu Lys Arg Cys  Ala Gln Glu 
        995                 1000                 1005             


Tyr Leu  Ser Arg Val Lys Lys  Glu Glu Gln Arg Tyr  Gln Ala Leu 
    1010                 1015                 1020             


Lys Val  His Ala Glu Glu Lys  Leu Asp Arg Ala Asn  Ala Glu Ile 
    1025                 1030                 1035             


Ala Gln  Val Arg Gly Lys Ala  Gln Gln Glu Gln Ala  Ala His Gln 
    1040                 1045                 1050             


Ala Ser  Leu Arg Lys Glu Gln  Leu Arg Val Asp Ala  Leu Glu Arg 
    1055                 1060                 1065             


Thr Leu  Glu Gln Lys Asn Lys  Glu Ile Glu Glu Leu  Thr Lys Ile 
    1070                 1075                 1080             


Cys Asp  Glu Leu Ile Ala Lys  Met Gly Lys Ser 
    1085                 1090                 


<210>  3135
<211>  902
<212>  PRT
<213>  homo sapiens

<400>  3135

Met Ala Asp Pro Glu Val Cys Cys Phe Ile Thr Lys Ile Leu Cys Ala 
1               5                   10                  15      


His Gly Gly Arg Met Ala Leu Asp Ala Leu Leu Gln Glu Ile Ala Leu 
            20                  25                  30          


Ser Glu Pro Gln Leu Cys Glu Val Leu Gln Val Ala Gly Pro Asp Arg 
        35                  40                  45              


Phe Val Val Leu Glu Thr Gly Gly Glu Ala Gly Ile Thr Arg Ser Val 
    50                  55                  60                  


Val Ala Thr Thr Arg Ala Arg Val Cys Arg Arg Lys Tyr Cys Gln Arg 
65                  70                  75                  80  


Pro Cys Asp Asn Leu His Leu Cys Lys Leu Asn Leu Leu Gly Arg Cys 
                85                  90                  95      


Asn Tyr Ser Gln Ser Glu Arg Asn Leu Cys Lys Tyr Ser His Glu Val 
            100                 105                 110         


Leu Ser Glu Glu Asn Phe Lys Val Leu Lys Asn His Glu Leu Ser Gly 
        115                 120                 125             


Leu Asn Lys Glu Glu Leu Ala Val Leu Leu Leu Gln Ser Asp Pro Phe 
    130                 135                 140                 


Phe Met Pro Glu Ile Cys Lys Ser Tyr Lys Gly Glu Gly Arg Gln Gln 
145                 150                 155                 160 


Ile Cys Asn Gln Gln Pro Pro Cys Ser Arg Leu His Ile Cys Asp His 
                165                 170                 175     


Phe Thr Arg Gly Asn Cys Arg Phe Pro Asn Cys Leu Arg Ser His Asn 
            180                 185                 190         


Leu Met Asp Arg Lys Val Leu Ala Ile Met Arg Glu His Gly Leu Asn 
        195                 200                 205             


Pro Asp Val Val Gln Asn Ile Gln Asp Ile Cys Asn Ser Lys His Met 
    210                 215                 220                 


Gln Lys Asn Pro Pro Gly Pro Arg Ala Pro Ser Ser His Arg Arg Asn 
225                 230                 235                 240 


Met Ala Tyr Arg Ala Arg Ser Lys Ser Arg Asp Arg Phe Phe Gln Gly 
                245                 250                 255     


Ser Gln Glu Phe Leu Ala Ser Ala Ser Ala Ser Ala Glu Arg Ser Cys 
            260                 265                 270         


Thr Pro Ser Pro Asp Gln Ile Ser His Arg Ala Ser Leu Glu Asp Ala 
        275                 280                 285             


Pro Val Asp Asp Leu Thr Arg Lys Phe Thr Tyr Leu Gly Ser Gln Asp 
    290                 295                 300                 


Arg Ala Arg Pro Pro Ser Gly Ser Ser Lys Ala Thr Asp Leu Gly Gly 
305                 310                 315                 320 


Thr Ser Gln Ala Gly Thr Ser Gln Arg Phe Leu Glu Asn Gly Ser Gln 
                325                 330                 335     


Glu Asp Leu Leu His Gly Asn Pro Gly Ser Thr Tyr Leu Ala Ser Asn 
            340                 345                 350         


Ser Thr Ser Ala Pro Asn Trp Lys Ser Leu Thr Ser Trp Thr Asn Asp 
        355                 360                 365             


Gln Gly Ala Arg Arg Lys Thr Val Phe Ser Pro Thr Leu Pro Ala Ala 
    370                 375                 380                 


Arg Ser Ser Leu Gly Ser Leu Gln Thr Pro Glu Ala Val Thr Thr Arg 
385                 390                 395                 400 


Lys Gly Thr Gly Leu Leu Ser Ser Asp Tyr Arg Ile Ile Asn Gly Lys 
                405                 410                 415     


Ser Gly Thr Gln Asp Ile Gln Pro Gly Pro Leu Phe Asn Asn Asn Ala 
            420                 425                 430         


Asp Gly Val Ala Thr Asp Ile Thr Ser Thr Arg Ser Leu Asn Tyr Lys 
        435                 440                 445             


Ser Thr Ser Ser Gly His Arg Glu Ile Ser Ser Pro Arg Ile Gln Asp 
    450                 455                 460                 


Ala Gly Pro Ala Ser Arg Asp Val Gln Ala Thr Gly Arg Ile Ala Asp 
465                 470                 475                 480 


Asp Ala Asp Pro Arg Val Ala Leu Val Asn Asp Ser Leu Ser Asp Val 
                485                 490                 495     


Thr Ser Thr Thr Ser Ser Arg Val Asp Asp His Asp Ser Glu Glu Ile 
            500                 505                 510         


Cys Leu Asp His Leu Cys Lys Gly Cys Pro Leu Asn Gly Ser Cys Ser 
        515                 520                 525             


Lys Val His Phe His Leu Pro Tyr Arg Trp Gln Met Leu Ile Gly Lys 
    530                 535                 540                 


Thr Trp Thr Asp Phe Glu His Met Glu Thr Ile Glu Lys Gly Tyr Cys 
545                 550                 555                 560 


Asn Pro Gly Ile His Leu Cys Ser Val Gly Ser Tyr Thr Ile Asn Phe 
                565                 570                 575     


Arg Val Met Ser Cys Asp Ser Phe Pro Ile Arg Arg Leu Ser Thr Pro 
            580                 585                 590         


Ser Ser Val Thr Lys Pro Ala Asn Ser Val Phe Thr Thr Lys Trp Ile 
        595                 600                 605             


Trp Tyr Trp Lys Asn Glu Ser Gly Thr Trp Ile Gln Tyr Gly Glu Glu 
    610                 615                 620                 


Lys Asp Lys Arg Lys Asn Ser Asn Val Asp Ser Ser Tyr Leu Glu Ser 
625                 630                 635                 640 


Leu Tyr Gln Ser Cys Pro Arg Gly Val Val Pro Phe Gln Ala Gly Ser 
                645                 650                 655     


Arg Asn Tyr Glu Leu Ser Phe Gln Gly Met Ile Gln Thr Asn Ile Ala 
            660                 665                 670         


Ser Lys Thr Gln Lys Asp Val Ile Arg Arg Pro Thr Phe Val Pro Gln 
        675                 680                 685             


Trp Tyr Val Gln Gln Met Lys Arg Gly Pro Asp His Gln Pro Ala Lys 
    690                 695                 700                 


Thr Ser Ser Val Ser Leu Thr Ala Thr Phe Arg Pro Gln Glu Asp Phe 
705                 710                 715                 720 


Cys Phe Leu Ser Ser Lys Lys Tyr Lys Leu Ser Glu Ile His His Leu 
                725                 730                 735     


His Pro Glu Tyr Val Arg Val Ser Glu His Phe Lys Ala Ser Met Lys 
            740                 745                 750         


Asn Phe Lys Ile Glu Lys Ile Lys Lys Ile Glu Asn Ser Glu Leu Leu 
        755                 760                 765             


Asp Lys Phe Thr Trp Lys Lys Ser Gln Met Lys Glu Glu Gly Lys Leu 
    770                 775                 780                 


Leu Phe Tyr Ala Thr Ser Arg Ala Tyr Val Glu Ser Ile Cys Ser Asn 
785                 790                 795                 800 


Asn Phe Asp Ser Phe Leu His Glu Thr His Glu Asn Lys Tyr Gly Lys 
                805                 810                 815     


Gly Ile Tyr Phe Ala Lys Asp Ala Ile Tyr Ser His Lys Asn Cys Pro 
            820                 825                 830         


Tyr Asp Ala Lys Asn Val Val Met Phe Val Ala Gln Val Leu Val Gly 
        835                 840                 845             


Lys Phe Thr Glu Gly Asn Ile Thr Tyr Thr Ser Pro Pro Pro Gln Phe 
    850                 855                 860                 


Asp Ser Cys Val Asp Thr Arg Ser Asn Pro Ser Val Phe Val Ile Phe 
865                 870                 875                 880 


Gln Lys Asp Gln Val Tyr Pro Gln Tyr Val Ile Glu Tyr Thr Glu Asp 
                885                 890                 895     


Lys Ala Cys Val Ile Ser 
            900         


<210>  3136
<211>  782
<212>  PRT
<213>  homo sapiens

<400>  3136

Met Ala Pro His Arg Pro Ala Pro Ala Leu Leu Cys Ala Leu Ser Leu 
1               5                   10                  15      


Ala Leu Cys Ala Leu Ser Leu Pro Val Arg Ala Ala Thr Ala Ser Arg 
            20                  25                  30          


Gly Ala Ser Gln Ala Gly Ala Pro Gln Gly Arg Val Pro Glu Ala Arg 
        35                  40                  45              


Pro Asn Ser Met Val Val Glu His Pro Glu Phe Leu Lys Ala Gly Lys 
    50                  55                  60                  


Glu Pro Gly Leu Gln Ile Trp Arg Val Glu Lys Phe Asp Leu Val Pro 
65                  70                  75                  80  


Val Pro Thr Asn Leu Tyr Gly Asp Phe Phe Thr Gly Asp Ala Tyr Val 
                85                  90                  95      


Ile Leu Lys Thr Val Gln Leu Arg Asn Gly Asn Leu Gln Tyr Asp Leu 
            100                 105                 110         


His Tyr Trp Leu Gly Asn Glu Cys Ser Gln Asp Glu Ser Gly Ala Ala 
        115                 120                 125             


Ala Ile Phe Thr Val Gln Leu Asp Asp Tyr Leu Asn Gly Arg Ala Val 
    130                 135                 140                 


Gln His Arg Glu Val Gln Gly Phe Glu Ser Ala Thr Phe Leu Gly Tyr 
145                 150                 155                 160 


Phe Lys Ser Gly Leu Lys Tyr Lys Lys Gly Gly Val Ala Ser Gly Phe 
                165                 170                 175     


Lys His Val Val Pro Asn Glu Val Val Val Gln Arg Leu Phe Gln Val 
            180                 185                 190         


Lys Gly Arg Arg Val Val Arg Ala Thr Glu Val Pro Val Ser Trp Glu 
        195                 200                 205             


Ser Phe Asn Asn Gly Asp Cys Phe Ile Leu Asp Leu Gly Asn Asn Ile 
    210                 215                 220                 


His Gln Trp Cys Gly Ser Asn Ser Asn Arg Tyr Glu Arg Leu Lys Ala 
225                 230                 235                 240 


Thr Gln Val Ser Lys Gly Ile Arg Asp Asn Glu Arg Ser Gly Arg Ala 
                245                 250                 255     


Arg Val His Val Ser Glu Glu Gly Thr Glu Pro Glu Ala Met Leu Gln 
            260                 265                 270         


Val Leu Gly Pro Lys Pro Ala Leu Pro Ala Gly Thr Glu Asp Thr Ala 
        275                 280                 285             


Lys Glu Asp Ala Ala Asn Arg Lys Leu Ala Lys Leu Tyr Lys Val Ser 
    290                 295                 300                 


Asn Gly Ala Gly Thr Met Ser Val Ser Leu Val Ala Asp Glu Asn Pro 
305                 310                 315                 320 


Phe Ala Gln Gly Ala Leu Lys Ser Glu Asp Cys Phe Ile Leu Asp His 
                325                 330                 335     


Gly Lys Asp Gly Lys Ile Phe Val Trp Lys Gly Lys Gln Ala Asn Thr 
            340                 345                 350         


Glu Glu Arg Lys Ala Ala Leu Lys Thr Ala Ser Asp Phe Ile Thr Lys 
        355                 360                 365             


Met Asp Tyr Pro Lys Gln Thr Gln Val Ser Val Leu Pro Glu Gly Gly 
    370                 375                 380                 


Glu Thr Pro Leu Phe Lys Gln Phe Phe Lys Asn Trp Arg Asp Pro Asp 
385                 390                 395                 400 


Gln Thr Asp Gly Leu Gly Leu Ser Tyr Leu Ser Ser His Ile Ala Asn 
                405                 410                 415     


Val Glu Arg Val Pro Phe Asp Ala Ala Thr Leu His Thr Ser Thr Ala 
            420                 425                 430         


Met Ala Ala Gln His Gly Met Asp Asp Asp Gly Thr Gly Gln Lys Gln 
        435                 440                 445             


Ile Trp Arg Ile Glu Gly Ser Asn Lys Val Pro Val Asp Pro Ala Thr 
    450                 455                 460                 


Tyr Gly Gln Phe Tyr Gly Gly Asp Ser Tyr Ile Ile Leu Tyr Asn Tyr 
465                 470                 475                 480 


Arg His Gly Gly Arg Gln Gly Gln Ile Ile Tyr Asn Trp Gln Gly Ala 
                485                 490                 495     


Gln Ser Thr Gln Asp Glu Val Ala Ala Ser Ala Ile Leu Thr Ala Gln 
            500                 505                 510         


Leu Asp Glu Glu Leu Gly Gly Thr Pro Val Gln Ser Arg Val Val Gln 
        515                 520                 525             


Gly Lys Glu Pro Ala His Leu Met Ser Leu Phe Gly Gly Lys Pro Met 
    530                 535                 540                 


Ile Ile Tyr Lys Gly Gly Thr Ser Arg Glu Gly Gly Gln Thr Ala Pro 
545                 550                 555                 560 


Ala Ser Thr Arg Leu Phe Gln Val Arg Ala Asn Ser Ala Gly Ala Thr 
                565                 570                 575     


Arg Ala Val Glu Val Leu Pro Lys Ala Gly Ala Leu Asn Ser Asn Asp 
            580                 585                 590         


Ala Phe Val Leu Lys Thr Pro Ser Ala Ala Tyr Leu Trp Val Gly Thr 
        595                 600                 605             


Gly Ala Ser Glu Ala Glu Lys Thr Gly Ala Gln Glu Leu Leu Arg Val 
    610                 615                 620                 


Leu Arg Ala Gln Pro Val Gln Val Ala Glu Gly Ser Glu Pro Asp Gly 
625                 630                 635                 640 


Phe Trp Glu Ala Leu Gly Gly Lys Ala Ala Tyr Arg Thr Ser Pro Arg 
                645                 650                 655     


Leu Lys Asp Lys Lys Met Asp Ala His Pro Pro Arg Leu Phe Ala Cys 
            660                 665                 670         


Ser Asn Lys Ile Gly Arg Phe Val Ile Glu Glu Val Pro Gly Glu Leu 
        675                 680                 685             


Met Gln Glu Asp Leu Ala Thr Asp Asp Val Met Leu Leu Asp Thr Trp 
    690                 695                 700                 


Asp Gln Val Phe Val Trp Val Gly Lys Asp Ser Gln Glu Glu Glu Lys 
705                 710                 715                 720 


Thr Glu Ala Leu Thr Ser Ala Lys Arg Tyr Ile Glu Thr Asp Pro Ala 
                725                 730                 735     


Asn Arg Asp Arg Arg Thr Pro Ile Thr Val Val Lys Gln Gly Phe Glu 
            740                 745                 750         


Pro Pro Ser Phe Val Gly Trp Phe Leu Gly Trp Asp Asp Asp Tyr Trp 
        755                 760                 765             


Ser Val Asp Pro Leu Asp Arg Ala Met Ala Glu Leu Ala Ala 
    770                 775                 780         


<210>  3137
<211>  632
<212>  PRT
<213>  homo sapiens

<400>  3137

Met Asn Gln Gly Ser Gly Leu Asp Leu Leu Lys Ile Ser Tyr Gly Lys 
1               5                   10                  15      


Gly Ala Arg Arg Lys Asn Arg Phe Lys Gly Ser Asp Gly Ser Thr Ser 
            20                  25                  30          


Ser Asp Thr Thr Ser Asn Ser Phe Val Arg Gln Gly Ser Ala Asp Ser 
        35                  40                  45              


Tyr Thr Ser Arg Pro Ser Asp Ser Asp Val Ser Leu Glu Glu Asp Arg 
    50                  55                  60                  


Glu Ala Val Arg Arg Glu Ala Glu Arg Gln Ala Gln Ala Gln Leu Glu 
65                  70                  75                  80  


Lys Ala Lys Thr Lys Pro Val Ala Phe Ala Val Arg Thr Asn Val Ser 
                85                  90                  95      


Tyr Ser Ala Ala His Glu Asp Asp Val Pro Val Pro Gly Met Ala Ile 
            100                 105                 110         


Ser Phe Glu Ala Lys Asp Phe Leu His Val Lys Glu Lys Phe Asn Asn 
        115                 120                 125             


Asp Trp Trp Ile Gly Arg Leu Val Lys Glu Gly Cys Glu Ile Gly Phe 
    130                 135                 140                 


Ile Pro Ser Pro Val Lys Leu Glu Asn Met Arg Leu Gln His Glu Gln 
145                 150                 155                 160 


Arg Ala Lys Gln Gly Lys Phe Tyr Ser Ser Lys Ser Gly Gly Asn Ser 
                165                 170                 175     


Ser Ser Ser Leu Gly Asp Ile Val Pro Ser Ser Arg Lys Ser Thr Pro 
            180                 185                 190         


Pro Ser Ser Ala Ile Asp Ile Asp Ala Thr Gly Leu Asp Ala Glu Glu 
        195                 200                 205             


Asn Asp Ile Pro Ala Asn His Arg Ser Pro Lys Pro Ser Ala Asn Ser 
    210                 215                 220                 


Val Thr Ser Pro His Ser Lys Glu Lys Arg Met Pro Phe Phe Lys Lys 
225                 230                 235                 240 


Thr Glu His Thr Pro Pro Tyr Asp Val Val Pro Ser Met Arg Pro Val 
                245                 250                 255     


Val Leu Val Gly Pro Ser Leu Lys Gly Tyr Glu Val Thr Asp Met Met 
            260                 265                 270         


Gln Lys Ala Leu Phe Asp Phe Leu Lys His Arg Phe Glu Gly Arg Ile 
        275                 280                 285             


Ser Ile Thr Arg Val Thr Ala Asp Ile Ser Leu Ala Lys Arg Ser Val 
    290                 295                 300                 


Leu Asn Asn Pro Ser Lys His Ala Ile Ile Glu Arg Ser Asn Thr Arg 
305                 310                 315                 320 


Ser Ser Leu Ala Glu Val Gln Ser Glu Ile Glu Arg Ile Phe Glu Leu 
                325                 330                 335     


Ala Arg Thr Leu Gln Leu Val Val Leu Asp Ala Asp Thr Ile Asn His 
            340                 345                 350         


Pro Ala Gln Leu Ser Lys Thr Ser Leu Ala Pro Ile Ile Val Tyr Val 
        355                 360                 365             


Lys Ile Ser Ser Pro Lys Val Leu Gln Arg Leu Ile Lys Ser Arg Gly 
    370                 375                 380                 


Lys Ser Gln Ala Lys His Leu Asn Val Gln Met Val Ala Ala Asp Lys 
385                 390                 395                 400 


Leu Ala Gln Cys Pro Pro Glu Leu Phe Asp Val Ile Leu Asp Glu Asn 
                405                 410                 415     


Gln Leu Glu Asp Ala Cys Glu His Leu Ala Asp Tyr Leu Glu Ala Tyr 
            420                 425                 430         


Trp Lys Ala Thr His Pro Pro Ser Ser Ser Leu Pro Asn Pro Leu Leu 
        435                 440                 445             


Ser Arg Thr Leu Ala Thr Ser Ser Leu Pro Leu Ser Pro Thr Leu Ala 
    450                 455                 460                 


Ser Asn Ser Gln Gly Ser Gln Gly Asp Gln Arg Thr Asp Arg Ser Ala 
465                 470                 475                 480 


Pro Ile Arg Ser Ala Ser Gln Ala Glu Glu Glu Pro Ser Val Glu Pro 
                485                 490                 495     


Val Lys Lys Ser Gln His Arg Ser Ser Ser Ser Ala Pro His His Asn 
            500                 505                 510         


His Arg Ser Gly Thr Ser Arg Gly Leu Ser Arg Gln Glu Thr Phe Asp 
        515                 520                 525             


Ser Glu Thr Gln Glu Ser Arg Asp Ser Ala Tyr Val Glu Pro Lys Glu 
    530                 535                 540                 


Asp Tyr Ser His Asp His Val Asp His Tyr Ala Ser His Arg Asp His 
545                 550                 555                 560 


Asn His Arg Asp Glu Thr His Gly Ser Ser Asp His Arg His Arg Glu 
                565                 570                 575     


Ser Arg His Arg Ser Arg Asp Val Asp Arg Glu Gln Asp His Asn Glu 
            580                 585                 590         


Cys Asn Lys Gln Arg Ser Arg His Lys Ser Lys Asp Arg Tyr Cys Glu 
        595                 600                 605             


Lys Asp Gly Glu Val Ile Ser Lys Lys Arg Asn Glu Ala Gly Glu Trp 
    610                 615                 620                 


Asn Arg Asp Val Tyr Ile Arg Gln 
625                 630         


<210>  3138
<211>  760
<212>  PRT
<213>  homo sapiens

<400>  3138

Met Ser Thr Val Glu Glu Asp Ser Asp Thr Val Thr Val Glu Thr Val 
1               5                   10                  15      


Asn Ser Val Thr Leu Thr Gln Asp Thr Glu Gly Asn Leu Ile Leu His 
            20                  25                  30          


Cys Pro Gln Asn Glu Ala Asp Glu Ile Asp Ser Glu Asp Ser Ile Glu 
        35                  40                  45              


Pro Pro His Lys Arg Leu Cys Leu Ser Ser Glu Asp Asp Gln Ser Ile 
    50                  55                  60                  


Asp Asp Ser Thr Pro Cys Ile Ser Val Val Ala Leu Pro Leu Ser Glu 
65                  70                  75                  80  


Asn Asp Gln Ser Phe Glu Val Thr Met Thr Ala Thr Thr Glu Val Ala 
                85                  90                  95      


Asp Asp Glu Val Thr Glu Gly Thr Val Thr Gln Ile Gln Ile Leu Gln 
            100                 105                 110         


Asn Glu Gln Leu Asp Glu Ile Ser Pro Leu Gly Asn Glu Glu Val Ser 
        115                 120                 125             


Ala Val Ser Gln Ala Trp Phe Thr Thr Lys Glu Asp Lys Asp Ser Leu 
    130                 135                 140                 


Thr Asn Lys Gly His Lys Trp Lys Gln Gly Met Trp Ser Lys Glu Glu 
145                 150                 155                 160 


Ile Asp Ile Leu Met Asn Asn Ile Glu Arg Tyr Leu Lys Ala Arg Gly 
                165                 170                 175     


Ile Lys Asp Ala Thr Glu Ile Ile Phe Glu Met Ser Lys Asp Glu Arg 
            180                 185                 190         


Lys Asp Phe Tyr Arg Thr Ile Ala Trp Gly Leu Asn Arg Pro Leu Phe 
        195                 200                 205             


Ala Val Tyr Arg Arg Val Leu Arg Met Tyr Asp Asp Arg Asn His Val 
    210                 215                 220                 


Gly Lys Tyr Thr Pro Glu Glu Ile Glu Lys Leu Lys Glu Leu Arg Ile 
225                 230                 235                 240 


Lys His Gly Asn Asp Trp Ala Thr Ile Gly Ala Ala Leu Gly Arg Ser 
                245                 250                 255     


Ala Ser Ser Val Lys Asp Arg Cys Arg Leu Met Lys Asp Thr Cys Asn 
            260                 265                 270         


Thr Gly Lys Trp Thr Glu Glu Glu Glu Lys Arg Leu Ala Glu Val Val 
        275                 280                 285             


His Glu Leu Thr Ser Thr Glu Pro Gly Asp Ile Val Thr Gln Gly Val 
    290                 295                 300                 


Ser Trp Ala Ala Val Ala Glu Arg Val Gly Thr Arg Ser Glu Lys Gln 
305                 310                 315                 320 


Cys Arg Ser Lys Trp Leu Asn Tyr Leu Asn Trp Lys Gln Ser Gly Gly 
                325                 330                 335     


Thr Glu Trp Thr Lys Glu Asp Glu Ile Asn Leu Ile Leu Arg Ile Ala 
            340                 345                 350         


Glu Leu Asp Val Ala Asp Glu Asn Asp Ile Asn Trp Asp Leu Leu Ala 
        355                 360                 365             


Glu Gly Trp Ser Ser Val Arg Ser Pro Gln Trp Leu Arg Ser Lys Trp 
    370                 375                 380                 


Trp Thr Ile Lys Arg Gln Ile Ala Asn His Lys Asp Val Ser Phe Pro 
385                 390                 395                 400 


Val Leu Ile Lys Gly Leu Lys Gln Leu His Glu Asn Gln Lys Asn Asn 
                405                 410                 415     


Pro Thr Leu Leu Glu Asn Lys Ser Gly Ser Gly Val Pro Asn Ser Asn 
            420                 425                 430         


Thr Asn Ser Ser Val Gln His Val Gln Ile Arg Val Ala Arg Leu Glu 
        435                 440                 445             


Asp Asn Thr Ala Ile Ser Ser Ser Pro Met Ala Ala Leu Gln Ile Pro 
    450                 455                 460                 


Val Gln Ile Thr His Val Ser Ser Ala Asp Ser Pro Ala Thr Val Asp 
465                 470                 475                 480 


Ser Glu Thr Ile Thr Leu Asn Ser Gly Thr Leu Gln Thr Phe Glu Ile 
                485                 490                 495     


Leu Pro Ser Phe His Leu Gln Pro Thr Gly Thr Pro Gly Thr Tyr Leu 
            500                 505                 510         


Leu Gln Thr Ser Ser Ser Gln Gly Leu Pro Leu Thr Leu Thr Ala Ser 
        515                 520                 525             


Pro Thr Val Thr Leu Thr Ala Ala Ala Pro Ala Ser Pro Glu Gln Ile 
    530                 535                 540                 


Ile Val His Ala Leu Ser Pro Glu His Leu Leu Asn Thr Ser Asp Asn 
545                 550                 555                 560 


Val Thr Val Gln Cys His Thr Pro Arg Val Ile Ile Gln Thr Val Ala 
                565                 570                 575     


Thr Glu Asp Ile Thr Ser Ser Ile Ser Gln Ala Glu Leu Thr Val Asp 
            580                 585                 590         


Ser Asp Ile Gln Ser Ser Asp Phe Pro Glu Pro Pro Asp Ala Leu Glu 
        595                 600                 605             


Ala Asp Thr Phe Pro Asp Glu Ile His His Pro Lys Met Thr Val Glu 
    610                 615                 620                 


Pro Ser Phe Asn Asp Ala His Val Ser Lys Phe Ser Asp Gln Asn Ser 
625                 630                 635                 640 


Thr Glu Leu Met Asn Ser Val Met Val Arg Thr Glu Glu Glu Ile Ser 
                645                 650                 655     


Asp Thr Asp Leu Lys Gln Glu Glu Ser Pro Ser Asp Leu Ala Ser Ala 
            660                 665                 670         


Tyr Val Thr Glu Gly Leu Glu Ser Pro Thr Ile Glu Glu Gln Val Asp 
        675                 680                 685             


Gln Thr Ile Asp Asp Glu Thr Ile Leu Ile Val Pro Ser Pro His Gly 
    690                 695                 700                 


Phe Ile Gln Ala Ser Asp Val Ile Asp Thr Glu Ser Val Leu Pro Leu 
705                 710                 715                 720 


Thr Thr Leu Thr Asp Pro Ile Leu Gln His His Gln Glu Glu Ser Asn 
                725                 730                 735     


Ile Ile Gly Ser Ser Leu Gly Ser Pro Val Ser Glu Asp Ser Lys Asp 
            740                 745                 750         


Val Glu Asp Leu Val Asn Cys His 
        755                 760 


<210>  3139
<211>  1476
<212>  PRT
<213>  homo sapiens

<400>  3139

Met Thr Ser Ser Ser Pro Ala Gly Leu Glu Gly Ser Asp Leu Ser Ser 
1               5                   10                  15      


Ile Asn Thr Met Met Ser Ala Val Met Ser Val Gly Lys Val Thr Glu 
            20                  25                  30          


Asn Gly Gly Ser Pro Gln Gly Ile Lys Ser Pro Ser Lys Pro Pro Gly 
        35                  40                  45              


Pro Asn Arg Ile Gly Arg Arg Asn Gln Glu Thr Lys Glu Glu Lys Ser 
    50                  55                  60                  


Ser Tyr Asn Cys Pro Leu Cys Glu Lys Ile Cys Thr Thr Gln His Gln 
65                  70                  75                  80  


Leu Thr Met His Ile Arg Gln His Asn Thr Asp Thr Gly Gly Ala Asp 
                85                  90                  95      


His Ser Cys Ser Ile Cys Gly Lys Ser Leu Ser Ser Ala Ser Ser Leu 
            100                 105                 110         


Asp Arg His Met Leu Val His Ser Gly Glu Arg Pro Tyr Lys Cys Thr 
        115                 120                 125             


Val Cys Gly Gln Ser Phe Thr Thr Asn Gly Asn Met His Arg His Met 
    130                 135                 140                 


Lys Ile His Glu Lys Asp Pro Asn Ser Ala Thr Ala Thr Ala Pro Pro 
145                 150                 155                 160 


Ser Pro Leu Lys Arg Arg Arg Leu Ser Ser Lys Arg Lys Leu Ser His 
                165                 170                 175     


Asp Ala Glu Ser Glu Arg Glu Asp Pro Ala Pro Ala Lys Lys Met Val 
            180                 185                 190         


Glu Asp Gly Gln Ser Gly Asp Leu Glu Lys Lys Ala Asp Glu Val Phe 
        195                 200                 205             


His Cys Pro Val Cys Phe Lys Glu Phe Val Cys Lys Tyr Gly Leu Glu 
    210                 215                 220                 


Thr His Met Glu Thr His Ser Asp Asn Pro Leu Arg Cys Asp Ile Cys 
225                 230                 235                 240 


Cys Val Thr Phe Arg Thr His Arg Gly Leu Leu Arg His Asn Ala Leu 
                245                 250                 255     


Val His Lys Gln Leu Pro Arg Asp Ala Met Gly Arg Pro Phe Ile Gln 
            260                 265                 270         


Asn Asn Pro Ser Ile Pro Ala Gly Phe His Asp Leu Gly Phe Thr Asp 
        275                 280                 285             


Phe Ser Cys Arg Lys Phe Pro Arg Ile Ser Gln Ala Trp Cys Glu Thr 
    290                 295                 300                 


Asn Leu Arg Arg Cys Ile Ser Glu Gln His Arg Phe Val Cys Asp Thr 
305                 310                 315                 320 


Cys Asp Lys Ala Phe Pro Met Leu Cys Ser Leu Ala Leu His Lys Gln 
                325                 330                 335     


Thr His Val Ala Ala Asp Gln Gly Gln Glu Lys Pro Gln Ala Thr Pro 
            340                 345                 350         


Leu Pro Gly Asp Ala Leu Asp Gln Lys Gly Phe Leu Ala Leu Leu Gly 
        355                 360                 365             


Leu Gln His Thr Lys Asp Val Arg Pro Ala Pro Ala Glu Glu Pro Leu 
    370                 375                 380                 


Pro Asp Asp Asn Gln Ala Ile Gln Leu Gln Thr Leu Lys Cys Gln Leu 
385                 390                 395                 400 


Pro Gln Asp Pro Gly Cys Thr Asn Leu Leu Ser Leu Ser Pro Phe Glu 
                405                 410                 415     


Ala Ala Ser Leu Gly Gly Ser Leu Thr Val Leu Pro Ala Thr Lys Asp 
            420                 425                 430         


Ser Ile Lys His Leu Ser Leu Gln Pro Phe Gln Lys Gly Phe Ile Ile 
        435                 440                 445             


Gln Pro Asp Ser Ser Ile Val Val Lys Pro Ile Ser Gly Glu Ser Ala 
    450                 455                 460                 


Ile Glu Leu Ala Asp Ile Gln Gln Ile Leu Lys Met Ala Ala Ser Ala 
465                 470                 475                 480 


Pro Pro Gln Ile Ser Leu Pro Pro Phe Ser Lys Ala Pro Ala Ala Pro 
                485                 490                 495     


Leu Gln Ala Ile Phe Lys His Met Pro Pro Leu Lys Pro Lys Pro Leu 
            500                 505                 510         


Val Thr Pro Arg Thr Val Val Ala Thr Ser Thr Pro Pro Pro Leu Ile 
        515                 520                 525             


Asn Ala Gln Gln Ala Ser Pro Gly Cys Ile Ser Pro Ser Leu Pro Pro 
    530                 535                 540                 


Pro Pro Leu Lys Leu Leu Lys Gly Ser Val Glu Ala Ala Ser Asn Ala 
545                 550                 555                 560 


His Leu Leu Gln Ser Lys Ser Gly Thr Gln Pro His Ala Ala Thr Arg 
                565                 570                 575     


Leu Ser Leu Gln Gln Pro Arg Ala Glu Leu Pro Gly Gln Pro Glu Met 
            580                 585                 590         


Lys Thr Gln Leu Glu Gln Asp Ser Ile Ile Glu Ala Leu Leu Pro Leu 
        595                 600                 605             


Ser Met Glu Ala Lys Ile Lys Gln Glu Ile Thr Glu Gly Glu Leu Lys 
    610                 615                 620                 


Ala Phe Met Thr Ala Pro Gly Gly Lys Lys Thr Pro Ala Met Arg Lys 
625                 630                 635                 640 


Val Leu Tyr Pro Cys Arg Phe Cys Asn Gln Val Phe Ala Phe Ser Gly 
                645                 650                 655     


Val Leu Arg Ala His Val Arg Ser His Leu Gly Ile Ser Pro Tyr Gln 
            660                 665                 670         


Cys Asn Ile Cys Asp Tyr Ile Ala Ala Asp Lys Ala Ala Leu Ile Arg 
        675                 680                 685             


His Leu Arg Thr His Ser Gly Glu Arg Pro Tyr Ile Cys Lys Ile Cys 
    690                 695                 700                 


His Tyr Pro Phe Thr Val Lys Ala Asn Cys Glu Arg His Leu Arg Lys 
705                 710                 715                 720 


Lys His Leu Lys Ala Thr Arg Lys Asp Ile Glu Lys Asn Ile Glu Tyr 
                725                 730                 735     


Val Ser Ser Ser Ala Ala Glu Leu Val Asp Ala Phe Cys Ala Pro Asp 
            740                 745                 750         


Thr Val Cys Arg Leu Cys Gly Glu Asp Leu Lys His Tyr Arg Ala Leu 
        755                 760                 765             


Arg Ile His Met Arg Thr His Cys Gly Arg Gly Leu Gly Gly Gly His 
    770                 775                 780                 


Lys Gly Arg Lys Pro Phe Glu Cys Lys Glu Cys Ser Ala Ala Phe Ala 
785                 790                 795                 800 


Ala Lys Arg Asn Cys Ile His His Ile Leu Lys Gln His Leu His Val 
                805                 810                 815     


Pro Glu Gln Asp Ile Glu Ser Tyr Val Leu Ala Ala Asp Gly Leu Gly 
            820                 825                 830         


Pro Ala Glu Ala Pro Ala Ala Glu Ala Ser Gly Arg Gly Glu Asp Ser 
        835                 840                 845             


Gly Cys Ala Ala Leu Gly Asp Cys Lys Pro Leu Thr Ala Phe Leu Glu 
    850                 855                 860                 


Pro Gln Asn Gly Phe Leu His Arg Gly Pro Thr Gln Pro Pro Pro Pro 
865                 870                 875                 880 


His Val Ser Ile Lys Leu Glu Pro Ala Ser Ser Phe Ala Val Asp Phe 
                885                 890                 895     


Asn Glu Pro Leu Asp Phe Ser Gln Lys Gly Leu Ala Leu Val Gln Val 
            900                 905                 910         


Lys Gln Glu Asn Ile Ser Phe Leu Ser Pro Ser Ser Leu Val Pro Tyr 
        915                 920                 925             


Asp Cys Ser Met Glu Pro Ile Asp Leu Ser Ile Pro Lys Asn Phe Arg 
    930                 935                 940                 


Lys Gly Asp Lys Asp Leu Ala Thr Pro Ser Glu Ala Lys Lys Pro Glu 
945                 950                 955                 960 


Glu Glu Ala Gly Ser Ser Glu Gln Pro Ser Pro Cys Pro Ala Pro Gly 
                965                 970                 975     


Pro Ser Leu Pro Val Thr Leu Gly Pro Ser Gly Ile Leu Glu Ser Pro 
            980                 985                 990         


Met Ala Pro Ala Pro Ala Ala Thr  Pro Glu Pro Pro Ala  Gln Pro Leu 
        995                 1000                 1005             


Gln Gly  Pro Val Gln Leu Ala  Val Pro Ile Tyr Ser  Ser Ala Leu 
    1010                 1015                 1020             


Val Ser  Ser Pro Pro Leu Val  Gly Ser Ser Ala Leu  Leu Ser Gly 
    1025                 1030                 1035             


Thr Ala  Leu Leu Arg Pro Leu  Arg Pro Lys Pro Pro  Leu Leu Leu 
    1040                 1045                 1050             


Pro Lys  Pro Pro Val Thr Glu  Glu Leu Pro Pro Leu  Ala Ser Ile 
    1055                 1060                 1065             


Ala Gln  Ile Ile Ser Ser Val  Ser Ser Ala Pro Thr  Leu Leu Lys 
    1070                 1075                 1080             


Thr Lys  Val Ala Asp Pro Gly  Pro Ala Ser Thr Gly  Ser Asn Thr 
    1085                 1090                 1095             


Thr Ala  Ser Asp Ser Leu Gly  Gly Ser Val Pro Lys  Ala Ala Thr 
    1100                 1105                 1110             


Thr Ala  Thr Pro Ala Ala Thr  Thr Ser Pro Lys Glu  Ser Ser Glu 
    1115                 1120                 1125             


Pro Pro  Ala Pro Ala Ser Ser  Pro Glu Ala Ala Ser  Pro Thr Glu 
    1130                 1135                 1140             


Gln Gly  Pro Ala Gly Thr Ser  Lys Lys Arg Gly Arg  Lys Arg Gly 
    1145                 1150                 1155             


Met Arg  Ser Arg Pro Arg Ala  Asn Ser Gly Gly Val  Asp Leu Asp 
    1160                 1165                 1170             


Ser Ser  Gly Glu Phe Ala Ser  Ile Glu Lys Met Leu  Ala Thr Thr 
    1175                 1180                 1185             


Asp Thr  Asn Lys Phe Ser Pro  Phe Leu Gln Thr Ala  Glu Asp Asn 
    1190                 1195                 1200             


Thr Gln  Asp Glu Val Ala Gly  Ala Pro Ala Asp His  His Gly Pro 
    1205                 1210                 1215             


Ser Asp  Glu Glu Gln Gly Ser  Pro Pro Glu Asp Lys  Leu Leu Arg 
    1220                 1225                 1230             


Ala Lys  Arg Asn Ser Tyr Thr  Asn Cys Leu Gln Lys  Ile Thr Cys 
    1235                 1240                 1245             


Pro His  Cys Pro Arg Val Phe  Pro Trp Ala Ser Ser  Leu Gln Arg 
    1250                 1255                 1260             


His Met  Leu Thr His Thr Gly  Gln Lys Pro Phe Pro  Cys Gln Lys 
    1265                 1270                 1275             


Cys Asp  Ala Phe Phe Ser Thr  Lys Ser Asn Cys Glu  Arg His Gln 
    1280                 1285                 1290             


Leu Arg  Lys His Gly Val Thr  Thr Cys Ser Leu Arg  Arg Asn Gly 
    1295                 1300                 1305             


Leu Ile  Pro Gln Ser Lys Glu  Ser Asp Val Gly Ser  His Asp Ser 
    1310                 1315                 1320             


Thr Gly  Glu Arg Pro Tyr Lys  Cys Gln Thr Cys Glu  Arg Thr Phe 
    1325                 1330                 1335             


Thr Leu  Lys His Ser Leu Val  Arg His Gln Arg Ile  His Gln Lys 
    1340                 1345                 1350             


Ala Arg  His Ala Lys His His  Gly Lys Asp Ser Asp  Lys Glu Glu 
    1355                 1360                 1365             


Arg Gly  Glu Glu Asp Ser Glu  Asn Glu Ser Thr His  Ser Gly Asn 
    1370                 1375                 1380             


Asn Ala  Val Ser Glu Asn Glu  Ala Glu Leu Ala Pro  Asn Ala Ser 
    1385                 1390                 1395             


Asn His  Met Ala Val Thr Arg  Ser Arg Lys Glu Gly  Leu Ala Ser 
    1400                 1405                 1410             


Ala Thr  Lys Asp Cys Ser His  Arg Glu Glu Lys Val  Thr Ala Gly 
    1415                 1420                 1425             


Trp Pro  Ser Glu Pro Gly Gln  Gly Asp Leu Asn Pro  Glu Ser Pro 
    1430                 1435                 1440             


Ala Ala  Leu Gly Gln Asp Leu  Leu Glu Pro Arg Ser  Lys Arg Pro 
    1445                 1450                 1455             


Ala His  Pro Ile Leu Ala Thr  Ala Asp Gly Ala Ser  Gln Leu Val 
    1460                 1465                 1470             


Gly Met  Glu 
    1475     


<210>  3140
<211>  1001
<212>  PRT
<213>  homo sapiens

<400>  3140

Met Ala Leu Pro Gln Ser Glu Asp Ala Met Thr Gly Asp Thr Asp Lys 
1               5                   10                  15      


Tyr Leu Gly Pro Gln Asp Leu Lys Glu Leu Gly Asp Asp Ser Leu Pro 
            20                  25                  30          


Ala Glu Gly Tyr Met Gly Phe Ser Leu Gly Ala Arg Ser Ala Ser Leu 
        35                  40                  45              


Arg Ser Phe Ser Ser Asp Arg Ser Tyr Thr Leu Asn Arg Ser Ser Tyr 
    50                  55                  60                  


Ala Arg Asp Ser Met Met Ile Glu Glu Leu Leu Val Pro Ser Lys Glu 
65                  70                  75                  80  


Gln His Leu Thr Phe Thr Arg Glu Phe Asp Ser Asp Ser Leu Arg His 
                85                  90                  95      


Tyr Ser Trp Ala Ala Asp Thr Leu Asp Asn Val Asn Leu Val Ser Ser 
            100                 105                 110         


Pro Ile His Ser Gly Phe Leu Val Ser Phe Met Val Asp Ala Arg Gly 
        115                 120                 125             


Gly Ser Met Arg Gly Ser Arg His His Gly Met Arg Ile Ile Ile Pro 
    130                 135                 140                 


Pro Arg Lys Cys Thr Ala Pro Thr Arg Ile Thr Cys Arg Leu Val Lys 
145                 150                 155                 160 


Arg His Lys Leu Ala Asn Pro Pro Pro Met Val Glu Gly Glu Gly Leu 
                165                 170                 175     


Ala Ser Arg Leu Val Glu Met Gly Pro Ala Gly Ala Gln Phe Leu Gly 
            180                 185                 190         


Pro Val Ile Val Glu Ile Pro His Phe Gly Ser Met Arg Gly Lys Glu 
        195                 200                 205             


Arg Glu Leu Ile Val Leu Arg Ser Glu Asn Gly Glu Thr Trp Lys Glu 
    210                 215                 220                 


His Gln Phe Asp Ser Lys Asn Glu Asp Leu Thr Glu Leu Leu Asn Gly 
225                 230                 235                 240 


Met Asp Glu Glu Leu Asp Ser Pro Glu Glu Leu Gly Lys Lys Arg Ile 
                245                 250                 255     


Cys Arg Ile Ile Thr Lys Asp Phe Pro Gln Tyr Phe Ala Val Val Ser 
            260                 265                 270         


Arg Ile Lys Gln Glu Ser Asn Gln Ile Gly Pro Glu Gly Gly Ile Leu 
        275                 280                 285             


Ser Ser Thr Thr Val Pro Leu Val Gln Ala Ser Phe Pro Glu Gly Ala 
    290                 295                 300                 


Leu Thr Lys Arg Ile Arg Val Gly Leu Gln Ala Gln Pro Val Pro Asp 
305                 310                 315                 320 


Glu Ile Val Lys Lys Ile Leu Gly Asn Lys Ala Thr Phe Ser Pro Ile 
                325                 330                 335     


Val Thr Val Glu Pro Arg Arg Arg Lys Phe His Lys Pro Ile Thr Met 
            340                 345                 350         


Thr Ile Pro Val Pro Pro Pro Ser Gly Glu Gly Val Ser Asn Gly Tyr 
        355                 360                 365             


Lys Gly Asp Thr Thr Pro Asn Leu Arg Leu Leu Cys Ser Ile Thr Gly 
    370                 375                 380                 


Gly Thr Ser Pro Ala Gln Trp Glu Asp Ile Thr Gly Thr Thr Pro Leu 
385                 390                 395                 400 


Thr Phe Ile Lys Asp Cys Val Ser Phe Thr Thr Asn Val Ser Ala Arg 
                405                 410                 415     


Phe Trp Leu Ala Asp Cys His Gln Val Leu Glu Thr Val Gly Leu Ala 
            420                 425                 430         


Thr Gln Leu Tyr Arg Glu Leu Ile Cys Val Pro Tyr Met Ala Lys Phe 
        435                 440                 445             


Val Val Phe Ala Lys Met Asn Asp Pro Val Glu Ser Ser Leu Arg Cys 
    450                 455                 460                 


Phe Cys Met Thr Asp Asp Lys Val Asp Lys Thr Leu Glu Gln Gln Glu 
465                 470                 475                 480 


Asn Phe Glu Glu Val Ala Arg Ser Lys Asp Ile Glu Val Leu Glu Gly 
                485                 490                 495     


Lys Pro Ile Tyr Val Asp Cys Tyr Gly Asn Leu Ala Pro Leu Thr Lys 
            500                 505                 510         


Gly Gly Gln Gln Leu Val Phe Asn Phe Tyr Ser Phe Lys Glu Asn Arg 
        515                 520                 525             


Leu Pro Phe Ser Ile Lys Ile Arg Asp Thr Ser Gln Glu Pro Cys Gly 
    530                 535                 540                 


Arg Leu Ser Phe Leu Lys Glu Pro Lys Thr Thr Lys Gly Leu Pro Gln 
545                 550                 555                 560 


Thr Ala Val Cys Asn Leu Asn Ile Thr Leu Pro Ala His Lys Lys Ile 
                565                 570                 575     


Glu Lys Thr Asp Arg Arg Gln Ser Phe Ala Ser Leu Ala Leu Arg Lys 
            580                 585                 590         


Arg Tyr Ser Tyr Leu Thr Glu Pro Gly Met Ser Pro Gln Ser Pro Cys 
        595                 600                 605             


Glu Arg Thr Asp Ile Arg Met Ala Ile Val Ala Asp His Leu Gly Leu 
    610                 615                 620                 


Ser Trp Thr Glu Leu Ala Arg Glu Leu Asn Phe Ser Val Asp Glu Ile 
625                 630                 635                 640 


Asn Gln Ile Arg Val Glu Asn Pro Asn Ser Leu Ile Ser Gln Ser Phe 
                645                 650                 655     


Met Leu Leu Lys Lys Trp Val Thr Arg Asp Gly Lys Asn Ala Thr Thr 
            660                 665                 670         


Asp Ala Leu Thr Ser Val Leu Thr Lys Ile Asn Arg Ile Asp Ile Val 
        675                 680                 685             


Thr Leu Leu Glu Gly Pro Ile Phe Asp Tyr Gly Asn Ile Ser Gly Thr 
    690                 695                 700                 


Arg Ser Phe Ala Asp Glu Asn Asn Val Phe His Asp Pro Val Asp Gly 
705                 710                 715                 720 


Tyr Pro Ser Leu Gln Val Glu Leu Glu Thr Pro Thr Gly Leu His Tyr 
                725                 730                 735     


Thr Pro Pro Thr Pro Phe Gln Gln Asp Asp Tyr Phe Ser Asp Ile Ser 
            740                 745                 750         


Ser Ile Glu Ser Pro Leu Arg Thr Pro Ser Arg Leu Ser Asp Gly Leu 
        755                 760                 765             


Val Pro Ser Gln Gly Asn Ile Glu His Ser Ala Asp Gly Pro Pro Val 
    770                 775                 780                 


Val Thr Ala Glu Asp Ala Ser Leu Glu Asp Ser Lys Leu Glu Asp Ser 
785                 790                 795                 800 


Val Pro Leu Thr Glu Met Pro Glu Ala Val Asp Val Asp Glu Ser Gln 
                805                 810                 815     


Leu Glu Asn Val Cys Leu Ser Trp Gln Asn Glu Thr Ser Ser Gly Asn 
            820                 825                 830         


Leu Glu Ser Cys Ala Gln Ala Arg Arg Val Thr Gly Gly Leu Leu Asp 
        835                 840                 845             


Arg Leu Asp Asp Ser Pro Asp Gln Cys Arg Asp Ser Ile Thr Ser Tyr 
    850                 855                 860                 


Leu Lys Gly Glu Ala Gly Lys Phe Glu Ala Asn Gly Ser His Thr Glu 
865                 870                 875                 880 


Ile Thr Pro Glu Ala Lys Thr Lys Ser Tyr Phe Pro Glu Ser Gln Asn 
                885                 890                 895     


Asp Val Gly Lys Gln Ser Thr Lys Glu Thr Leu Lys Pro Lys Ile His 
            900                 905                 910         


Gly Ser Gly His Val Glu Glu Pro Ala Ser Pro Leu Ala Ala Tyr Gln 
        915                 920                 925             


Lys Ser Leu Glu Glu Thr Ser Lys Leu Ile Ile Glu Glu Thr Lys Pro 
    930                 935                 940                 


Cys Val Pro Val Ser Met Lys Lys Met Ser Arg Thr Ser Pro Ala Asp 
945                 950                 955                 960 


Gly Lys Pro Arg Leu Ser Leu His Glu Glu Glu Gly Ser Ser Gly Ser 
                965                 970                 975     


Glu Gln Lys Gln Gly Glu Gly Phe Lys Val Lys Thr Lys Lys Glu Ile 
            980                 985                 990         


Arg His Val Glu Lys Lys Ser His  Ser 
        995                 1000     


<210>  3141
<211>  901
<212>  PRT
<213>  homo sapiens

<400>  3141

Met Glu Ala Ala Arg Pro Ser Gly Ser Trp Asn Gly Ala Leu Cys Arg 
1               5                   10                  15      


Leu Leu Leu Leu Thr Leu Ala Ile Leu Ile Phe Ala Ser Asp Ala Cys 
            20                  25                  30          


Lys Asn Val Thr Leu His Val Pro Ser Lys Leu Asp Ala Glu Lys Leu 
        35                  40                  45              


Val Gly Arg Val Asn Leu Lys Glu Cys Phe Thr Ala Ala Asn Leu Ile 
    50                  55                  60                  


His Ser Ser Asp Pro Asp Phe Gln Ile Leu Glu Asp Gly Ser Val Tyr 
65                  70                  75                  80  


Thr Thr Asn Thr Ile Leu Leu Ser Ser Glu Lys Arg Ser Phe Thr Ile 
                85                  90                  95      


Leu Leu Ser Asn Thr Glu Asn Gln Glu Lys Lys Lys Ile Phe Val Phe 
            100                 105                 110         


Leu Glu His Gln Thr Lys Val Leu Lys Lys Arg His Thr Lys Glu Lys 
        115                 120                 125             


Val Leu Arg Arg Ala Lys Arg Arg Trp Ala Pro Ile Pro Cys Ser Met 
    130                 135                 140                 


Leu Glu Asn Ser Leu Gly Pro Phe Pro Leu Phe Leu Gln Gln Val Gln 
145                 150                 155                 160 


Ser Asp Thr Ala Gln Asn Tyr Thr Ile Tyr Tyr Ser Ile Arg Gly Pro 
                165                 170                 175     


Gly Val Asp Gln Glu Pro Arg Asn Leu Phe Tyr Val Glu Arg Asp Thr 
            180                 185                 190         


Gly Asn Leu Tyr Cys Thr Arg Pro Val Asp Arg Glu Gln Tyr Glu Ser 
        195                 200                 205             


Phe Glu Ile Ile Ala Phe Ala Thr Thr Pro Asp Gly Tyr Thr Pro Glu 
    210                 215                 220                 


Leu Pro Leu Pro Leu Ile Ile Lys Ile Glu Asp Glu Asn Asp Asn Tyr 
225                 230                 235                 240 


Pro Ile Phe Thr Glu Glu Thr Tyr Thr Phe Thr Ile Phe Glu Asn Cys 
                245                 250                 255     


Arg Val Gly Thr Thr Val Gly Gln Val Cys Ala Thr Asp Lys Asp Glu 
            260                 265                 270         


Pro Asp Thr Met His Thr Arg Leu Lys Tyr Ser Ile Ile Gly Gln Val 
        275                 280                 285             


Pro Pro Ser Pro Thr Leu Phe Ser Met His Pro Thr Thr Gly Val Ile 
    290                 295                 300                 


Thr Thr Thr Ser Ser Gln Leu Asp Arg Glu Leu Ile Asp Lys Tyr Gln 
305                 310                 315                 320 


Leu Lys Ile Lys Val Gln Asp Met Asp Gly Gln Tyr Phe Gly Leu Gln 
                325                 330                 335     


Thr Thr Ser Thr Cys Ile Ile Asn Ile Asp Asp Val Asn Asp His Leu 
            340                 345                 350         


Pro Thr Phe Thr Arg Thr Ser Tyr Val Thr Ser Val Glu Glu Asn Thr 
        355                 360                 365             


Val Asp Val Glu Ile Leu Arg Val Thr Val Glu Asp Lys Asp Leu Val 
    370                 375                 380                 


Asn Thr Ala Asn Trp Arg Ala Asn Tyr Thr Ile Leu Lys Gly Asn Glu 
385                 390                 395                 400 


Asn Gly Asn Phe Lys Ile Val Thr Asp Ala Lys Thr Asn Glu Gly Val 
                405                 410                 415     


Leu Cys Val Val Lys Pro Leu Asn Tyr Glu Glu Lys Gln Gln Met Ile 
            420                 425                 430         


Leu Gln Ile Gly Val Val Asn Glu Ala Pro Phe Ser Arg Glu Ala Ser 
        435                 440                 445             


Pro Arg Ser Ala Met Ser Thr Ala Thr Val Thr Val Asn Val Glu Asp 
    450                 455                 460                 


Gln Asp Glu Gly Pro Glu Cys Asn Pro Pro Ile Gln Thr Val Arg Met 
465                 470                 475                 480 


Lys Glu Asn Ala Glu Val Gly Thr Thr Ser Asn Gly Tyr Lys Ala Tyr 
                485                 490                 495     


Asp Pro Glu Thr Arg Ser Ser Ser Gly Ile Arg Tyr Lys Lys Leu Thr 
            500                 505                 510         


Asp Pro Thr Gly Trp Val Thr Ile Asp Glu Asn Thr Gly Ser Ile Lys 
        515                 520                 525             


Val Phe Arg Ser Leu Asp Arg Glu Ala Glu Thr Ile Lys Asn Gly Ile 
    530                 535                 540                 


Tyr Asn Ile Thr Val Leu Ala Ser Asp Gln Gly Gly Arg Thr Cys Thr 
545                 550                 555                 560 


Gly Thr Leu Gly Ile Ile Leu Gln Asp Val Asn Asp Asn Ser Pro Phe 
                565                 570                 575     


Ile Pro Lys Lys Thr Val Ile Ile Cys Lys Pro Thr Met Ser Ser Ala 
            580                 585                 590         


Glu Ile Val Ala Val Asp Pro Asp Glu Pro Ile His Gly Pro Pro Phe 
        595                 600                 605             


Asp Phe Ser Leu Glu Ser Ser Thr Ser Glu Val Gln Arg Met Trp Arg 
    610                 615                 620                 


Leu Lys Ala Ile Asn Asp Thr Ala Ala Arg Leu Ser Tyr Gln Asn Asp 
625                 630                 635                 640 


Pro Pro Phe Gly Ser Tyr Val Val Pro Ile Thr Val Arg Asp Arg Leu 
                645                 650                 655     


Gly Met Ser Ser Val Thr Ser Leu Asp Val Thr Leu Cys Asp Cys Ile 
            660                 665                 670         


Thr Glu Asn Asp Cys Thr His Arg Val Asp Pro Arg Ile Gly Gly Gly 
        675                 680                 685             


Gly Val Gln Leu Gly Lys Trp Ala Ile Leu Ala Ile Leu Leu Gly Ile 
    690                 695                 700                 


Ala Leu Leu Phe Cys Ile Leu Phe Thr Leu Val Cys Gly Ala Ser Gly 
705                 710                 715                 720 


Thr Ser Lys Gln Pro Lys Val Ile Pro Asp Asp Leu Ala Gln Gln Asn 
                725                 730                 735     


Leu Ile Val Ser Asn Thr Glu Ala Pro Gly Asp Asp Lys Val Tyr Ser 
            740                 745                 750         


Ala Asn Gly Phe Thr Thr Gln Thr Val Gly Ala Ser Ala Gln Gly Val 
        755                 760                 765             


Cys Gly Thr Val Gly Ser Gly Ile Lys Asn Gly Gly Gln Glu Thr Ile 
    770                 775                 780                 


Glu Met Val Lys Gly Gly His Gln Thr Ser Glu Ser Cys Arg Gly Ala 
785                 790                 795                 800 


Gly His His His Thr Leu Asp Ser Cys Arg Gly Gly His Thr Glu Val 
                805                 810                 815     


Asp Asn Cys Arg Tyr Thr Tyr Ser Glu Trp His Ser Phe Thr Gln Pro 
            820                 825                 830         


Arg Leu Gly Glu Lys Val Tyr Leu Cys Asn Gln Asp Glu Asn His Lys 
        835                 840                 845             


His Ala Gln Asp Tyr Val Leu Thr Tyr Asn Tyr Glu Gly Arg Gly Ser 
    850                 855                 860                 


Val Ala Gly Ser Val Gly Cys Cys Ser Glu Arg Gln Glu Glu Asp Gly 
865                 870                 875                 880 


Leu Glu Phe Leu Asp Asn Leu Glu Pro Lys Phe Arg Thr Leu Ala Glu 
                885                 890                 895     


Ala Cys Met Lys Arg 
            900     


<210>  3142
<211>  358
<212>  PRT
<213>  homo sapiens

<400>  3142

Met Arg Ala Thr Pro Leu Ala Ala Pro Ala Gly Ser Leu Ser Arg Lys 
1               5                   10                  15      


Lys Arg Leu Glu Leu Asp Asp Asn Leu Asp Thr Glu Arg Pro Val Gln 
            20                  25                  30          


Lys Arg Ala Arg Ser Gly Pro Gln Pro Arg Leu Pro Pro Cys Leu Leu 
        35                  40                  45              


Pro Leu Ser Pro Pro Thr Ala Pro Asp Arg Ala Thr Ala Val Ala Thr 
    50                  55                  60                  


Ala Ser Arg Leu Gly Pro Tyr Val Leu Leu Glu Pro Glu Glu Gly Gly 
65                  70                  75                  80  


Arg Ala Tyr Gln Ala Leu His Cys Pro Thr Gly Thr Glu Tyr Thr Cys 
                85                  90                  95      


Lys Val Tyr Pro Val Gln Glu Ala Leu Ala Val Leu Glu Pro Tyr Ala 
            100                 105                 110         


Arg Leu Pro Pro His Lys His Val Ala Arg Pro Thr Glu Val Leu Ala 
        115                 120                 125             


Gly Thr Gln Leu Leu Tyr Ala Phe Phe Thr Arg Thr His Gly Asp Met 
    130                 135                 140                 


His Ser Leu Val Arg Ser Arg His Arg Ile Pro Glu Pro Glu Ala Ala 
145                 150                 155                 160 


Val Leu Phe Arg Gln Met Ala Thr Ala Leu Ala His Cys His Gln His 
                165                 170                 175     


Gly Leu Val Leu Arg Asp Leu Lys Leu Cys Arg Phe Val Phe Ala Asp 
            180                 185                 190         


Arg Glu Arg Lys Lys Leu Val Leu Glu Asn Leu Glu Asp Ser Cys Val 
        195                 200                 205             


Leu Thr Gly Pro Asp Asp Ser Leu Trp Asp Lys His Ala Cys Pro Ala 
    210                 215                 220                 


Tyr Val Gly Pro Glu Ile Leu Ser Ser Arg Ala Ser Tyr Ser Gly Lys 
225                 230                 235                 240 


Ala Ala Asp Val Trp Ser Leu Gly Val Ala Leu Phe Thr Met Leu Ala 
                245                 250                 255     


Gly His Tyr Pro Phe Gln Asp Ser Glu Pro Val Leu Leu Phe Gly Lys 
            260                 265                 270         


Ile Arg Arg Gly Ala Tyr Ala Leu Pro Ala Gly Leu Ser Ala Pro Ala 
        275                 280                 285             


Arg Cys Leu Val Arg Cys Leu Leu Arg Arg Glu Pro Ala Glu Arg Leu 
    290                 295                 300                 


Thr Ala Thr Gly Ile Leu Leu His Pro Trp Leu Arg Gln Asp Pro Met 
305                 310                 315                 320 


Pro Leu Ala Pro Thr Arg Ser His Leu Trp Glu Ala Ala Gln Val Val 
                325                 330                 335     


Pro Asp Gly Leu Gly Leu Asp Glu Ala Arg Glu Glu Glu Gly Asp Arg 
            340                 345                 350         


Glu Val Val Leu Tyr Gly 
        355             


<210>  3143
<211>  975
<212>  PRT
<213>  homo sapiens

<400>  3143

Met Ala Thr Gly Leu Gly Glu Pro Val Tyr Gly Leu Ser Glu Asp Glu 
1               5                   10                  15      


Gly Glu Ser Arg Ile Leu Arg Val Lys Val Val Ser Gly Ile Asp Leu 
            20                  25                  30          


Ala Lys Lys Asp Ile Phe Gly Ala Ser Asp Pro Tyr Val Lys Leu Ser 
        35                  40                  45              


Leu Tyr Val Ala Asp Glu Asn Arg Glu Leu Ala Leu Val Gln Thr Lys 
    50                  55                  60                  


Thr Ile Lys Lys Thr Leu Asn Pro Lys Trp Asn Glu Glu Phe Tyr Phe 
65                  70                  75                  80  


Arg Val Asn Pro Ser Asn His Arg Leu Leu Phe Glu Val Phe Asp Glu 
                85                  90                  95      


Asn Arg Leu Thr Arg Asp Asp Phe Leu Gly Gln Val Asp Val Pro Leu 
            100                 105                 110         


Ser His Leu Pro Thr Glu Asp Pro Thr Met Glu Arg Pro Tyr Thr Phe 
        115                 120                 125             


Lys Asp Phe Leu Leu Arg Pro Arg Ser His Lys Ser Arg Val Lys Gly 
    130                 135                 140                 


Phe Leu Arg Leu Lys Met Ala Tyr Met Pro Lys Asn Gly Gly Gln Asp 
145                 150                 155                 160 


Glu Glu Asn Ser Asp Gln Arg Asp Asp Met Glu His Gly Trp Glu Val 
                165                 170                 175     


Val Asp Ser Asn Asp Ser Ala Ser Gln His Gln Glu Glu Leu Pro Pro 
            180                 185                 190         


Pro Pro Leu Pro Pro Gly Trp Glu Glu Lys Val Asp Asn Leu Gly Arg 
        195                 200                 205             


Thr Tyr Tyr Val Asn His Asn Asn Arg Thr Thr Gln Trp His Arg Pro 
    210                 215                 220                 


Ser Leu Met Asp Val Ser Ser Glu Ser Asp Asn Asn Ile Arg Gln Ile 
225                 230                 235                 240 


Asn Gln Glu Ala Ala His Arg Arg Phe Arg Ser Arg Arg His Ile Ser 
                245                 250                 255     


Glu Asp Leu Glu Pro Glu Pro Ser Glu Gly Gly Asp Val Pro Glu Pro 
            260                 265                 270         


Trp Glu Thr Ile Ser Glu Glu Val Asn Ile Ala Gly Asp Ser Leu Gly 
        275                 280                 285             


Leu Ala Leu Pro Pro Pro Pro Ala Ser Pro Gly Ser Arg Thr Ser Pro 
    290                 295                 300                 


Gln Glu Leu Ser Glu Glu Leu Ser Arg Arg Leu Gln Ile Thr Pro Asp 
305                 310                 315                 320 


Ser Asn Gly Glu Gln Phe Ser Ser Leu Ile Gln Arg Glu Pro Ser Ser 
                325                 330                 335     


Arg Leu Arg Ser Cys Ser Val Thr Asp Ala Val Ala Glu Gln Gly His 
            340                 345                 350         


Leu Pro Pro Pro Ser Ala Pro Ala Gly Arg Ala Arg Ser Ser Thr Val 
        355                 360                 365             


Thr Gly Gly Glu Glu Pro Thr Pro Ser Val Ala Tyr Val His Thr Thr 
    370                 375                 380                 


Pro Gly Leu Pro Ser Gly Trp Glu Glu Arg Lys Asp Ala Lys Gly Arg 
385                 390                 395                 400 


Thr Tyr Tyr Val Asn His Asn Asn Arg Thr Thr Thr Trp Thr Arg Pro 
                405                 410                 415     


Ile Met Gln Leu Ala Glu Asp Gly Ala Ser Gly Ser Ala Thr Asn Ser 
            420                 425                 430         


Asn Asn His Leu Ile Glu Pro Gln Ile Arg Arg Pro Arg Ser Leu Ser 
        435                 440                 445             


Ser Pro Thr Val Thr Leu Ser Ala Pro Leu Glu Gly Ala Lys Asp Ser 
    450                 455                 460                 


Pro Val Arg Arg Ala Val Lys Asp Thr Leu Ser Asn Pro Gln Ser Pro 
465                 470                 475                 480 


Gln Pro Ser Pro Tyr Asn Ser Pro Lys Pro Gln His Lys Val Thr Gln 
                485                 490                 495     


Ser Phe Leu Pro Pro Gly Trp Glu Met Arg Ile Ala Pro Asn Gly Arg 
            500                 505                 510         


Pro Phe Phe Ile Asp His Asn Thr Lys Thr Thr Thr Trp Glu Asp Pro 
        515                 520                 525             


Arg Leu Lys Phe Pro Val His Met Arg Ser Lys Thr Ser Leu Asn Pro 
    530                 535                 540                 


Asn Asp Leu Gly Pro Leu Pro Pro Gly Trp Glu Glu Arg Ile His Leu 
545                 550                 555                 560 


Asp Gly Arg Thr Phe Tyr Ile Asp His Asn Ser Lys Ile Thr Gln Trp 
                565                 570                 575     


Glu Asp Pro Arg Leu Gln Asn Pro Ala Ile Thr Gly Pro Ala Val Pro 
            580                 585                 590         


Tyr Ser Arg Glu Phe Lys Gln Lys Tyr Asp Tyr Phe Arg Lys Lys Leu 
        595                 600                 605             


Lys Lys Pro Ala Asp Ile Pro Asn Arg Phe Glu Met Lys Leu His Arg 
    610                 615                 620                 


Asn Asn Ile Phe Glu Glu Ser Tyr Arg Arg Ile Met Ser Val Lys Arg 
625                 630                 635                 640 


Pro Asp Val Leu Lys Ala Arg Leu Trp Ile Glu Phe Glu Ser Glu Lys 
                645                 650                 655     


Gly Leu Asp Tyr Gly Gly Val Ala Arg Glu Trp Phe Phe Leu Leu Ser 
            660                 665                 670         


Lys Glu Met Phe Asn Pro Tyr Tyr Gly Leu Phe Glu Tyr Ser Ala Thr 
        675                 680                 685             


Asp Asn Tyr Thr Leu Gln Ile Asn Pro Asn Ser Gly Leu Cys Asn Glu 
    690                 695                 700                 


Asp His Leu Ser Tyr Phe Thr Phe Ile Gly Arg Val Ala Gly Leu Ala 
705                 710                 715                 720 


Val Phe His Gly Lys Leu Leu Asp Gly Phe Phe Ile Arg Pro Phe Tyr 
                725                 730                 735     


Lys Met Met Leu Gly Lys Gln Ile Thr Leu Asn Asp Met Glu Ser Val 
            740                 745                 750         


Asp Ser Glu Tyr Tyr Asn Ser Leu Lys Trp Ile Leu Glu Asn Asp Pro 
        755                 760                 765             


Thr Glu Leu Asp Leu Met Phe Cys Ile Asp Glu Glu Asn Phe Gly Gln 
    770                 775                 780                 


Thr Tyr Gln Val Asp Leu Lys Pro Asn Gly Ser Glu Ile Met Val Thr 
785                 790                 795                 800 


Asn Glu Asn Lys Arg Glu Tyr Ile Asp Leu Val Ile Gln Trp Arg Phe 
                805                 810                 815     


Val Asn Arg Val Gln Lys Gln Met Asn Ala Phe Leu Glu Gly Phe Thr 
            820                 825                 830         


Glu Leu Leu Pro Ile Asp Leu Ile Lys Ile Phe Asp Glu Asn Glu Leu 
        835                 840                 845             


Glu Leu Leu Met Cys Gly Leu Gly Asp Val Asp Val Asn Asp Trp Arg 
    850                 855                 860                 


Gln His Ser Ile Tyr Lys Asn Gly Tyr Cys Pro Asn His Pro Val Ile 
865                 870                 875                 880 


Gln Trp Phe Trp Lys Ala Val Leu Leu Met Asp Ala Glu Lys Arg Ile 
                885                 890                 895     


Arg Leu Leu Gln Phe Val Thr Gly Thr Ser Arg Val Pro Met Asn Gly 
            900                 905                 910         


Phe Ala Glu Leu Tyr Gly Ser Asn Gly Pro Gln Leu Phe Thr Ile Glu 
        915                 920                 925             


Gln Trp Gly Ser Pro Glu Lys Leu Pro Arg Ala His Thr Cys Phe Asn 
    930                 935                 940                 


Arg Leu Asp Leu Pro Pro Tyr Glu Thr Phe Glu Asp Leu Arg Glu Lys 
945                 950                 955                 960 


Leu Leu Met Ala Val Glu Asn Ala Gln Gly Phe Glu Gly Val Asp 
                965                 970                 975 


<210>  3144
<211>  444
<212>  PRT
<213>  homo sapiens

<400>  3144

Met Glu Pro Pro Gly Pro Val Arg Gly Pro Leu Gln Asp Ser Ser Trp 
1               5                   10                  15      


Tyr Glu Pro Ser Ala Glu Leu Val Gln Thr Arg Met Ala Val Ser Leu 
            20                  25                  30          


Thr Ala Ala Glu Thr Leu Ala Leu Gln Gly Thr Gln Gly Gln Glu Lys 
        35                  40                  45              


Met Met Met Met Gly Pro Lys Glu Glu Glu Gln Ser Cys Glu Tyr Glu 
    50                  55                  60                  


Thr Arg Leu Pro Gly Asn His Ser Thr Ser Gln Glu Ile Phe Arg Gln 
65                  70                  75                  80  


Arg Phe Arg His Leu Arg Tyr Gln Glu Thr Pro Gly Pro Arg Glu Ala 
                85                  90                  95      


Leu Ser Gln Leu Arg Val Leu Cys Cys Glu Trp Leu Arg Pro Glu Lys 
            100                 105                 110         


His Thr Lys Glu Gln Ile Leu Glu Phe Leu Val Leu Glu Gln Phe Leu 
        115                 120                 125             


Thr Ile Leu Pro Glu Glu Leu Gln Ser Trp Val Arg Gly His His Pro 
    130                 135                 140                 


Lys Ser Gly Glu Glu Ala Val Thr Val Leu Glu Asp Leu Glu Lys Gly 
145                 150                 155                 160 


Leu Glu Pro Glu Pro Gln Val Pro Gly Pro Ala His Gly Pro Ala Gln 
                165                 170                 175     


Glu Glu Pro Trp Glu Lys Lys Glu Ser Leu Gly Ala Ala Gln Glu Ala 
            180                 185                 190         


Leu Ser Ile Gln Leu Gln Pro Lys Glu Thr Gln Pro Phe Pro Lys Ser 
        195                 200                 205             


Glu Gln Val Tyr Leu His Phe Leu Ser Val Val Thr Glu Asp Gly Pro 
    210                 215                 220                 


Glu Pro Lys Asp Lys Gly Ser Leu Pro Gln Pro Pro Ile Thr Glu Val 
225                 230                 235                 240 


Glu Ser Gln Val Phe Ser Glu Lys Leu Ala Thr Asp Thr Ser Thr Phe 
                245                 250                 255     


Glu Ala Thr Ser Glu Gly Thr Leu Glu Leu Gln Gln Arg Asn Pro Lys 
            260                 265                 270         


Ala Glu Arg Leu Arg Trp Ser Pro Ala Gln Glu Glu Ser Phe Arg Gln 
        275                 280                 285             


Met Val Val Ile His Lys Glu Ile Pro Thr Gly Lys Lys Asp His Glu 
    290                 295                 300                 


Cys Ser Glu Cys Gly Lys Thr Phe Ile Tyr Asn Ser His Leu Val Val 
305                 310                 315                 320 


His Gln Arg Val His Ser Gly Glu Lys Pro Tyr Lys Cys Ser Asp Cys 
                325                 330                 335     


Gly Lys Thr Phe Lys Gln Ser Ser Asn Leu Gly Gln His Gln Arg Ile 
            340                 345                 350         


His Thr Gly Glu Lys Pro Phe Glu Cys Asn Glu Cys Gly Lys Ala Phe 
        355                 360                 365             


Arg Trp Gly Ala His Leu Val Gln His Gln Arg Ile His Ser Gly Glu 
    370                 375                 380                 


Lys Pro Tyr Glu Cys Asn Glu Cys Gly Lys Ala Phe Ser Gln Ser Ser 
385                 390                 395                 400 


Tyr Leu Ser Gln His Arg Arg Ile His Ser Gly Glu Lys Pro Phe Ile 
                405                 410                 415     


Cys Lys Glu Cys Gly Lys Ala Tyr Gly Trp Cys Ser Glu Leu Ile Arg 
            420                 425                 430         


His Arg Arg Val His Ala Arg Lys Glu Pro Ser His 
        435                 440                 


<210>  3145
<211>  97
<212>  PRT
<213>  homo sapiens

<400>  3145

Met Asn Gln Glu Asn Pro Pro Pro Tyr Pro Gly Pro Gly Pro Thr Ala 
1               5                   10                  15      


Pro Tyr Pro Pro Tyr Pro Pro Gln Pro Met Gly Pro Gly Pro Met Gly 
            20                  25                  30          


Gly Pro Tyr Pro Pro Pro Gln Gly Tyr Pro Tyr Gln Gly Tyr Pro Gln 
        35                  40                  45              


Tyr Gly Trp Gln Gly Gly Pro Gln Glu Pro Pro Lys Thr Thr Val Tyr 
    50                  55                  60                  


Val Val Glu Asp Gln Arg Arg Asp Glu Leu Gly Pro Ser Thr Cys Leu 
65                  70                  75                  80  


Thr Ala Cys Trp Thr Ala Leu Cys Cys Cys Cys Leu Trp Asp Met Leu 
                85                  90                  95      


Thr 
    


<210>  3146
<211>  253
<212>  PRT
<213>  homo sapiens

<400>  3146

Met Met Ala Gln Ser Lys Ala Asn Gly Ser His Tyr Ala Leu Thr Ala 
1               5                   10                  15      


Ile Gly Leu Gly Met Leu Val Leu Gly Val Ile Met Ala Met Trp Asn 
            20                  25                  30          


Leu Val Pro Gly Phe Ser Ala Ala Glu Lys Pro Thr Ala Gln Gly Ser 
        35                  40                  45              


Asn Lys Thr Glu Val Gly Gly Gly Ile Leu Lys Ser Lys Thr Phe Ser 
    50                  55                  60                  


Val Ala Tyr Val Leu Val Gly Ala Gly Val Met Leu Leu Leu Leu Ser 
65                  70                  75                  80  


Ile Cys Leu Ser Ile Arg Asp Lys Arg Lys Gln Arg Gln Gly Glu Asp 
                85                  90                  95      


Leu Ala His Val Gln His Pro Thr Gly Ala Gly Pro His Ala Gln Glu 
            100                 105                 110         


Glu Asp Ser Gln Glu Glu Glu Glu Glu Asp Glu Glu Ala Ala Ser Arg 
        115                 120                 125             


Tyr Tyr Val Pro Ser Tyr Glu Glu Val Met Asn Thr Asn Tyr Ser Glu 
    130                 135                 140                 


Ala Arg Gly Glu Glu Gln Asn Pro Arg Leu Ser Ile Ser Leu Pro Ser 
145                 150                 155                 160 


Tyr Glu Ser Leu Thr Gly Leu Asp Glu Thr Thr Pro Thr Ser Thr Arg 
                165                 170                 175     


Ala Asp Val Glu Ala Ser Pro Gly Asn Pro Pro Asp Arg Gln Asn Ser 
            180                 185                 190         


Lys Leu Ala Lys Arg Leu Lys Pro Leu Lys Val Arg Arg Ile Lys Ser 
        195                 200                 205             


Glu Lys Leu His Leu Lys Asp Phe Arg Ile Asn Leu Pro Asp Lys Asn 
    210                 215                 220                 


Val Pro Pro Pro Ser Ile Glu Pro Leu Thr Pro Pro Pro Gln Tyr Asp 
225                 230                 235                 240 


Glu Val Gln Glu Lys Ala Pro Asp Thr Arg Pro Pro Asp 
                245                 250             


<210>  3147
<211>  253
<212>  PRT
<213>  homo sapiens

<400>  3147

Met Met Ala Gln Ser Lys Ala Asn Gly Ser His Tyr Ala Leu Thr Ala 
1               5                   10                  15      


Ile Gly Leu Gly Met Leu Val Leu Gly Val Ile Met Ala Met Trp Asn 
            20                  25                  30          


Leu Val Pro Gly Phe Ser Ala Ala Glu Lys Pro Thr Ala Gln Gly Ser 
        35                  40                  45              


Asn Lys Thr Glu Val Gly Gly Gly Ile Leu Lys Ser Lys Thr Phe Ser 
    50                  55                  60                  


Val Ala Tyr Val Leu Val Gly Ala Gly Val Met Leu Leu Leu Leu Ser 
65                  70                  75                  80  


Ile Cys Leu Ser Ile Arg Asp Lys Arg Lys Gln Arg Gln Gly Glu Asp 
                85                  90                  95      


Leu Ala His Val Gln His Pro Thr Gly Ala Gly Pro His Ala Gln Glu 
            100                 105                 110         


Glu Asp Ser Gln Glu Glu Glu Glu Glu Asp Glu Glu Ala Ala Ser Arg 
        115                 120                 125             


Tyr Tyr Val Pro Ser Tyr Glu Glu Val Met Asn Thr Asn Tyr Ser Glu 
    130                 135                 140                 


Ala Arg Gly Glu Glu Gln Asn Pro Arg Leu Ser Ile Ser Leu Pro Ser 
145                 150                 155                 160 


Tyr Glu Ser Leu Thr Gly Leu Asp Glu Thr Thr Pro Thr Ser Thr Arg 
                165                 170                 175     


Ala Asp Val Glu Ala Ser Pro Gly Asn Pro Pro Asp Arg Gln Asn Ser 
            180                 185                 190         


Lys Leu Ala Lys Arg Leu Lys Pro Leu Lys Val Arg Arg Ile Lys Ser 
        195                 200                 205             


Glu Lys Leu His Leu Lys Asp Phe Arg Ile Asn Leu Pro Asp Lys Asn 
    210                 215                 220                 


Val Pro Pro Pro Ser Ile Glu Pro Leu Thr Pro Pro Pro Gln Tyr Asp 
225                 230                 235                 240 


Glu Val Gln Glu Lys Ala Pro Asp Thr Arg Pro Pro Asp 
                245                 250             


<210>  3148
<211>  257
<212>  PRT
<213>  homo sapiens

<400>  3148

Met Ala Ala Asp Gly Val Asp Glu Arg Ser Pro Leu Leu Ser Ala Ser 
1               5                   10                  15      


His Ser Gly Asn Val Thr Pro Thr Ala Pro Pro Tyr Leu Gln Glu Ser 
            20                  25                  30          


Ser Pro Arg Ala Glu Leu Pro Pro Pro Tyr Thr Ala Ile Ala Ser Pro 
        35                  40                  45              


Asp Ala Ser Gly Ile Pro Val Ile Asn Cys Arg Val Cys Gln Ser Leu 
    50                  55                  60                  


Ile Asn Leu Asp Gly Lys Leu His Gln His Val Val Lys Cys Thr Val 
65                  70                  75                  80  


Cys Asn Glu Ala Thr Pro Ile Lys Asn Pro Pro Thr Gly Lys Lys Tyr 
                85                  90                  95      


Val Arg Cys Pro Cys Asn Cys Leu Leu Ile Cys Lys Asp Thr Ser Arg 
            100                 105                 110         


Arg Ile Gly Cys Pro Arg Pro Asn Cys Arg Arg Ile Ile Asn Leu Gly 
        115                 120                 125             


Pro Val Met Leu Ile Ser Glu Glu Gln Pro Ala Gln Pro Ala Leu Pro 
    130                 135                 140                 


Ile Gln Pro Glu Gly Thr Arg Val Val Cys Gly His Cys Gly Asn Thr 
145                 150                 155                 160 


Phe Leu Trp Met Glu Leu Arg Phe Asn Thr Leu Ala Lys Cys Pro His 
                165                 170                 175     


Cys Lys Lys Ile Ser Ser Val Gly Ser Ala Leu Pro Arg Arg Arg Cys 
            180                 185                 190         


Cys Ala Tyr Ile Thr Ile Gly Met Ile Cys Ile Phe Ile Gly Val Gly 
        195                 200                 205             


Leu Thr Val Gly Thr Pro Asp Phe Ala Arg Arg Phe Arg Ala Thr Tyr 
    210                 215                 220                 


Val Ser Trp Ala Ile Ala Tyr Leu Leu Gly Leu Ile Cys Leu Ile Arg 
225                 230                 235                 240 


Ala Cys Tyr Trp Gly Ala Ile Arg Val Ser Tyr Pro Glu His Ser Phe 
                245                 250                 255     


Ala 
    


<210>  3149
<211>  334
<212>  PRT
<213>  homo sapiens

<400>  3149

Met Ser Ala Leu Leu Arg Leu Leu Arg Thr Gly Ala Pro Ala Ala Ala 
1               5                   10                  15      


Cys Leu Arg Leu Gly Thr Ser Ala Gly Thr Gly Ser Arg Arg Ala Met 
            20                  25                  30          


Ala Leu Tyr His Thr Glu Glu Arg Gly Gln Pro Cys Ser Gln Asn Tyr 
        35                  40                  45              


Arg Leu Phe Phe Lys Asn Val Thr Gly His Tyr Ile Ser Pro Phe His 
    50                  55                  60                  


Asp Ile Pro Leu Lys Val Asn Ser Lys Glu Glu Asn Gly Ile Pro Met 
65                  70                  75                  80  


Lys Lys Ala Arg Asn Asp Glu Tyr Glu Asn Leu Phe Asn Met Ile Val 
                85                  90                  95      


Glu Ile Pro Arg Trp Thr Asn Ala Lys Met Glu Ile Ala Thr Lys Glu 
            100                 105                 110         


Pro Met Asn Pro Ile Lys Gln Tyr Val Lys Asp Gly Lys Leu Arg Tyr 
        115                 120                 125             


Val Ala Asn Ile Phe Pro Tyr Lys Gly Tyr Ile Trp Asn Tyr Gly Thr 
    130                 135                 140                 


Leu Pro Gln Thr Trp Glu Asp Pro His Glu Lys Asp Lys Ser Thr Asn 
145                 150                 155                 160 


Cys Phe Gly Asp Asn Asp Pro Ile Asp Val Cys Glu Ile Gly Ser Lys 
                165                 170                 175     


Ile Leu Ser Cys Gly Glu Val Ile His Val Lys Ile Leu Gly Ile Leu 
            180                 185                 190         


Ala Leu Ile Asp Glu Gly Glu Thr Asp Trp Lys Leu Ile Ala Ile Asn 
        195                 200                 205             


Ala Asn Asp Pro Glu Ala Ser Lys Phe His Asp Ile Asp Asp Val Lys 
    210                 215                 220                 


Lys Phe Lys Pro Gly Tyr Leu Glu Ala Thr Leu Asn Trp Phe Arg Leu 
225                 230                 235                 240 


Tyr Lys Val Pro Asp Gly Lys Pro Glu Asn Gln Phe Ala Phe Asn Gly 
                245                 250                 255     


Glu Phe Lys Asn Lys Ala Phe Ala Leu Glu Val Ile Lys Ser Thr His 
            260                 265                 270         


Gln Cys Trp Lys Ala Leu Leu Met Lys Lys Cys Asn Gly Gly Ala Ile 
        275                 280                 285             


Asn Cys Thr Asn Val Gln Ile Ser Asp Ser Pro Phe Arg Cys Thr Gln 
    290                 295                 300                 


Glu Glu Ala Arg Ser Leu Val Glu Ser Val Ser Ser Ser Pro Asn Lys 
305                 310                 315                 320 


Glu Ser Asn Glu Glu Glu Gln Val Trp His Phe Leu Gly Lys 
                325                 330                 


<210>  3150
<211>  845
<212>  PRT
<213>  homo sapiens

<400>  3150

Met Leu Ser Gly Val Trp Phe Leu Ser Val Leu Thr Val Ala Gly Ile 
1               5                   10                  15      


Leu Gln Thr Glu Ser Arg Lys Thr Ala Lys Asp Ile Cys Lys Ile Arg 
            20                  25                  30          


Cys Leu Cys Glu Glu Lys Glu Asn Val Leu Asn Ile Asn Cys Glu Asn 
        35                  40                  45              


Lys Gly Phe Thr Thr Val Ser Leu Leu Gln Pro Pro Gln Tyr Arg Ile 
    50                  55                  60                  


Tyr Gln Leu Phe Leu Asn Gly Asn Leu Leu Thr Arg Leu Tyr Pro Asn 
65                  70                  75                  80  


Glu Phe Val Asn Tyr Ser Asn Ala Val Thr Leu His Leu Gly Asn Asn 
                85                  90                  95      


Gly Leu Gln Glu Ile Arg Thr Gly Ala Phe Ser Gly Leu Lys Thr Leu 
            100                 105                 110         


Lys Arg Leu His Leu Asn Asn Asn Lys Leu Glu Ile Leu Arg Glu Asp 
        115                 120                 125             


Thr Phe Leu Gly Leu Glu Ser Leu Glu Tyr Leu Gln Ala Asp Tyr Asn 
    130                 135                 140                 


Tyr Ile Ser Ala Ile Glu Ala Gly Ala Phe Ser Lys Leu Asn Lys Leu 
145                 150                 155                 160 


Lys Val Leu Ile Leu Asn Asp Asn Leu Leu Leu Ser Leu Pro Ser Asn 
                165                 170                 175     


Val Phe Arg Phe Val Leu Leu Thr His Leu Asp Leu Arg Gly Asn Arg 
            180                 185                 190         


Leu Lys Val Met Pro Phe Ala Gly Val Leu Glu His Ile Gly Gly Ile 
        195                 200                 205             


Met Glu Ile Gln Leu Glu Glu Asn Pro Trp Asn Cys Thr Cys Asp Leu 
    210                 215                 220                 


Leu Pro Leu Lys Ala Trp Leu Asp Thr Ile Thr Val Phe Val Gly Glu 
225                 230                 235                 240 


Ile Val Cys Glu Thr Pro Phe Arg Leu His Gly Lys Asp Val Thr Gln 
                245                 250                 255     


Leu Thr Arg Gln Asp Leu Cys Pro Arg Lys Ser Ala Ser Asp Ser Ser 
            260                 265                 270         


Gln Arg Gly Ser His Ala Asp Thr His Val Gln Arg Leu Ser Pro Thr 
        275                 280                 285             


Met Asn Pro Ala Leu Asn Pro Thr Arg Ala Pro Lys Ala Ser Arg Pro 
    290                 295                 300                 


Pro Lys Met Arg Asn Arg Pro Thr Pro Arg Val Thr Val Ser Lys Asp 
305                 310                 315                 320 


Arg Gln Ser Phe Gly Pro Ile Met Val Tyr Gln Thr Lys Ser Pro Val 
                325                 330                 335     


Pro Leu Thr Cys Pro Ser Ser Cys Val Cys Thr Ser Gln Ser Ser Asp 
            340                 345                 350         


Asn Gly Leu Asn Val Asn Cys Gln Glu Arg Lys Phe Thr Asn Ile Ser 
        355                 360                 365             


Asp Leu Gln Pro Lys Pro Thr Ser Pro Lys Lys Leu Tyr Leu Thr Gly 
    370                 375                 380                 


Asn Tyr Leu Gln Thr Val Tyr Lys Asn Asp Leu Leu Glu Tyr Ser Ser 
385                 390                 395                 400 


Leu Asp Leu Leu His Leu Gly Asn Asn Arg Ile Ala Val Ile Gln Glu 
                405                 410                 415     


Gly Ala Phe Thr Asn Leu Thr Ser Leu Arg Arg Leu Tyr Leu Asn Gly 
            420                 425                 430         


Asn Tyr Leu Glu Val Leu Tyr Pro Ser Met Phe Asp Gly Leu Gln Ser 
        435                 440                 445             


Leu Gln Tyr Leu Tyr Leu Glu Tyr Asn Val Ile Lys Glu Ile Lys Pro 
    450                 455                 460                 


Leu Thr Phe Asp Ala Leu Ile Asn Leu Gln Leu Leu Phe Leu Asn Asn 
465                 470                 475                 480 


Asn Leu Leu Arg Ser Leu Pro Asp Asn Ile Phe Gly Gly Thr Ala Leu 
                485                 490                 495     


Thr Arg Leu Asn Leu Arg Asn Asn His Phe Ser His Leu Pro Val Lys 
            500                 505                 510         


Gly Val Leu Asp Gln Leu Pro Ala Phe Ile Gln Ile Asp Leu Gln Glu 
        515                 520                 525             


Asn Pro Trp Asp Cys Thr Cys Asp Ile Met Gly Leu Lys Asp Trp Thr 
    530                 535                 540                 


Glu His Ala Asn Ser Pro Val Ile Ile Asn Glu Val Thr Cys Glu Ser 
545                 550                 555                 560 


Pro Ala Lys His Ala Gly Glu Ile Leu Lys Phe Leu Gly Arg Glu Ala 
                565                 570                 575     


Ile Cys Pro Asp Ser Pro Asn Leu Ser Asp Gly Thr Val Leu Ser Met 
            580                 585                 590         


Asn His Asn Thr Asp Thr Pro Arg Ser Leu Ser Val Ser Pro Ser Ser 
        595                 600                 605             


Tyr Pro Glu Leu His Thr Glu Val Pro Leu Ser Val Leu Ile Leu Gly 
    610                 615                 620                 


Leu Leu Val Val Phe Ile Leu Ser Val Cys Phe Gly Ala Gly Leu Phe 
625                 630                 635                 640 


Val Phe Val Leu Lys Arg Arg Lys Gly Val Pro Ser Val Pro Arg Asn 
                645                 650                 655     


Thr Asn Asn Leu Asp Val Ser Ser Phe Gln Leu Gln Tyr Gly Ser Tyr 
            660                 665                 670         


Asn Thr Glu Thr His Asp Lys Thr Asp Gly His Val Tyr Asn Tyr Ile 
        675                 680                 685             


Pro Pro Pro Val Gly Gln Met Cys Gln Asn Pro Ile Tyr Met Gln Lys 
    690                 695                 700                 


Glu Gly Asp Pro Val Ala Tyr Tyr Arg Asn Leu Gln Glu Phe Ser Tyr 
705                 710                 715                 720 


Ser Asn Leu Glu Glu Lys Lys Glu Glu Pro Ala Thr Pro Ala Tyr Thr 
                725                 730                 735     


Ile Ser Ala Thr Glu Leu Leu Glu Lys Gln Ala Thr Pro Arg Glu Pro 
            740                 745                 750         


Glu Leu Leu Tyr Gln Asn Ile Ala Glu Arg Val Lys Glu Leu Pro Ser 
        755                 760                 765             


Ala Gly Leu Val His Tyr Asn Phe Cys Thr Leu Pro Lys Arg Gln Phe 
    770                 775                 780                 


Ala Pro Ser Tyr Glu Ser Arg Arg Gln Asn Gln Asp Arg Ile Asn Lys 
785                 790                 795                 800 


Thr Val Leu Tyr Gly Thr Pro Arg Lys Cys Phe Val Gly Gln Ser Lys 
                805                 810                 815     


Pro Asn His Pro Leu Leu Gln Ala Lys Pro Gln Ser Glu Pro Asp Tyr 
            820                 825                 830         


Leu Glu Val Leu Glu Lys Gln Thr Ala Ile Ser Gln Leu 
        835                 840                 845 


<210>  3151
<211>  4377
<212>  PRT
<213>  homo sapiens

<400>  3151

Met Ala His Ala Ala Ser Gln Leu Lys Lys Asn Arg Asp Leu Glu Ile 
1               5                   10                  15      


Asn Ala Glu Glu Glu Pro Glu Lys Lys Arg Lys His Arg Lys Arg Ser 
            20                  25                  30          


Arg Asp Arg Lys Lys Lys Ser Asp Ala Asn Ala Ser Tyr Leu Arg Ala 
        35                  40                  45              


Ala Arg Ala Gly His Leu Glu Lys Ala Leu Asp Tyr Ile Lys Asn Gly 
    50                  55                  60                  


Val Asp Ile Asn Ile Cys Asn Gln Asn Gly Leu Asn Ala Leu His Leu 
65                  70                  75                  80  


Ala Ser Lys Glu Gly His Val Glu Val Val Ser Glu Leu Leu Gln Arg 
                85                  90                  95      


Glu Ala Asn Val Asp Ala Ala Thr Lys Lys Gly Asn Thr Ala Leu His 
            100                 105                 110         


Ile Ala Ser Leu Ala Gly Gln Ala Glu Val Val Lys Val Leu Val Thr 
        115                 120                 125             


Asn Gly Ala Asn Val Asn Ala Gln Ser Gln Asn Gly Phe Thr Pro Leu 
    130                 135                 140                 


Tyr Met Ala Ala Gln Glu Asn His Leu Glu Val Val Lys Phe Leu Leu 
145                 150                 155                 160 


Asp Asn Gly Ala Ser Gln Ser Leu Ala Thr Glu Asp Gly Phe Thr Pro 
                165                 170                 175     


Leu Ala Val Ala Leu Gln Gln Gly His Asp Gln Val Val Ser Leu Leu 
            180                 185                 190         


Leu Glu Asn Asp Thr Lys Gly Lys Val Arg Leu Pro Ala Leu His Ile 
        195                 200                 205             


Ala Ala Arg Lys Asp Asp Thr Lys Ala Ala Ala Leu Leu Leu Gln Asn 
    210                 215                 220                 


Asp Asn Asn Ala Asp Val Glu Ser Lys Ser Gly Phe Thr Pro Leu His 
225                 230                 235                 240 


Ile Ala Ala His Tyr Gly Asn Ile Asn Val Ala Thr Leu Leu Leu Asn 
                245                 250                 255     


Arg Ala Ala Ala Val Asp Phe Thr Ala Arg Asn Asp Ile Thr Pro Leu 
            260                 265                 270         


His Val Ala Ser Lys Arg Gly Asn Ala Asn Met Val Lys Leu Leu Leu 
        275                 280                 285             


Asp Arg Gly Ala Lys Ile Asp Ala Lys Thr Arg Asp Gly Leu Thr Pro 
    290                 295                 300                 


Leu His Cys Gly Ala Arg Ser Gly His Glu Gln Val Val Glu Met Leu 
305                 310                 315                 320 


Leu Asp Arg Ala Ala Pro Ile Leu Ser Lys Thr Lys Asn Gly Leu Ser 
                325                 330                 335     


Pro Leu His Met Ala Thr Gln Gly Asp His Leu Asn Cys Val Gln Leu 
            340                 345                 350         


Leu Leu Gln His Asn Val Pro Val Asp Asp Val Thr Asn Asp Tyr Leu 
        355                 360                 365             


Thr Ala Leu His Val Ala Ala His Cys Gly His Tyr Lys Val Ala Lys 
    370                 375                 380                 


Val Leu Leu Asp Lys Lys Ala Asn Pro Asn Ala Lys Ala Leu Asn Gly 
385                 390                 395                 400 


Phe Thr Pro Leu His Ile Ala Cys Lys Lys Asn Arg Ile Lys Val Met 
                405                 410                 415     


Glu Leu Leu Leu Lys His Gly Ala Ser Ile Gln Ala Val Thr Glu Ser 
            420                 425                 430         


Gly Leu Thr Pro Ile His Val Ala Ala Phe Met Gly His Val Asn Ile 
        435                 440                 445             


Val Ser Gln Leu Met His His Gly Ala Ser Pro Asn Thr Thr Asn Val 
    450                 455                 460                 


Arg Gly Glu Thr Ala Leu His Met Ala Ala Arg Ser Gly Gln Ala Glu 
465                 470                 475                 480 


Val Val Arg Tyr Leu Val Gln Asp Gly Ala Gln Val Glu Ala Lys Ala 
                485                 490                 495     


Lys Asp Asp Gln Thr Pro Leu His Ile Ser Ala Arg Leu Gly Lys Ala 
            500                 505                 510         


Asp Ile Val Gln Gln Leu Leu Gln Gln Gly Ala Ser Pro Asn Ala Ala 
        515                 520                 525             


Thr Thr Ser Gly Tyr Thr Pro Leu His Leu Ser Ala Arg Glu Gly His 
    530                 535                 540                 


Glu Asp Val Ala Ala Phe Leu Leu Asp His Gly Ala Ser Leu Ser Ile 
545                 550                 555                 560 


Thr Thr Lys Lys Gly Phe Thr Pro Leu His Val Ala Ala Lys Tyr Gly 
                565                 570                 575     


Lys Leu Glu Val Ala Asn Leu Leu Leu Gln Lys Ser Ala Ser Pro Asp 
            580                 585                 590         


Ala Ala Gly Lys Ser Gly Leu Thr Pro Leu His Val Ala Ala His Tyr 
        595                 600                 605             


Asp Asn Gln Lys Val Ala Leu Leu Leu Leu Asp Gln Gly Ala Ser Pro 
    610                 615                 620                 


His Ala Ala Ala Lys Asn Gly Tyr Thr Pro Leu His Ile Ala Ala Lys 
625                 630                 635                 640 


Lys Asn Gln Met Asp Ile Ala Thr Thr Leu Leu Glu Tyr Gly Ala Asp 
                645                 650                 655     


Ala Asn Ala Val Thr Arg Gln Gly Ile Ala Ser Val His Leu Ala Ala 
            660                 665                 670         


Gln Glu Gly His Val Asp Met Val Ser Leu Leu Leu Gly Arg Asn Ala 
        675                 680                 685             


Asn Val Asn Leu Ser Asn Lys Ser Gly Leu Thr Pro Leu His Leu Ala 
    690                 695                 700                 


Ala Gln Glu Asp Arg Val Asn Val Ala Glu Val Leu Val Asn Gln Gly 
705                 710                 715                 720 


Ala His Val Asp Ala Gln Thr Lys Met Gly Tyr Thr Pro Leu His Val 
                725                 730                 735     


Gly Cys His Tyr Gly Asn Ile Lys Ile Val Asn Phe Leu Leu Gln His 
            740                 745                 750         


Ser Ala Lys Val Asn Ala Lys Thr Lys Asn Gly Tyr Thr Pro Leu His 
        755                 760                 765             


Gln Ala Ala Gln Gln Gly His Thr His Ile Ile Asn Val Leu Leu Gln 
    770                 775                 780                 


Asn Asn Ala Ser Pro Asn Glu Leu Thr Val Asn Gly Asn Thr Ala Leu 
785                 790                 795                 800 


Gly Ile Ala Arg Arg Leu Gly Tyr Ile Ser Val Val Asp Thr Leu Lys 
                805                 810                 815     


Ile Val Thr Glu Glu Thr Met Thr Thr Thr Thr Val Thr Glu Lys His 
            820                 825                 830         


Lys Met Asn Val Pro Glu Thr Met Asn Glu Val Leu Asp Met Ser Asp 
        835                 840                 845             


Asp Glu Val Arg Lys Ala Asn Ala Pro Glu Met Leu Ser Asp Gly Glu 
    850                 855                 860                 


Tyr Ile Ser Asp Val Glu Glu Gly Glu Asp Ala Met Thr Gly Asp Thr 
865                 870                 875                 880 


Asp Lys Tyr Leu Gly Pro Gln Asp Leu Lys Glu Leu Gly Asp Asp Ser 
                885                 890                 895     


Leu Pro Ala Glu Gly Tyr Met Gly Phe Ser Leu Gly Ala Arg Ser Ala 
            900                 905                 910         


Ser Leu Arg Ser Phe Ser Ser Asp Arg Ser Tyr Thr Leu Asn Arg Ser 
        915                 920                 925             


Ser Tyr Ala Arg Asp Ser Met Met Ile Glu Glu Leu Leu Val Pro Ser 
    930                 935                 940                 


Lys Glu Gln His Leu Thr Phe Thr Arg Glu Phe Asp Ser Asp Ser Leu 
945                 950                 955                 960 


Arg His Tyr Ser Trp Ala Ala Asp Thr Leu Asp Asn Val Asn Leu Val 
                965                 970                 975     


Ser Ser Pro Ile His Ser Gly Phe Leu Val Ser Phe Met Val Asp Ala 
            980                 985                 990         


Arg Gly Gly Ser Met Arg Gly Ser  Arg His His Gly Met  Arg Ile Ile 
        995                 1000                 1005             


Ile Pro  Pro Arg Lys Cys Thr  Ala Pro Thr Arg Ile  Thr Cys Arg 
    1010                 1015                 1020             


Leu Val  Lys Arg His Lys Leu  Ala Asn Pro Pro Pro  Met Val Glu 
    1025                 1030                 1035             


Gly Glu  Gly Leu Ala Ser Arg  Leu Val Glu Met Gly  Pro Ala Gly 
    1040                 1045                 1050             


Ala Gln  Phe Leu Gly Pro Val  Ile Val Glu Ile Pro  His Phe Gly 
    1055                 1060                 1065             


Ser Met  Arg Gly Lys Glu Arg  Glu Leu Ile Val Leu  Arg Ser Glu 
    1070                 1075                 1080             


Asn Gly  Glu Thr Trp Lys Glu  His Gln Phe Asp Ser  Lys Asn Glu 
    1085                 1090                 1095             


Asp Leu  Thr Glu Leu Leu Asn  Gly Met Asp Glu Glu  Leu Asp Ser 
    1100                 1105                 1110             


Pro Glu  Glu Leu Gly Lys Lys  Arg Ile Cys Arg Ile  Ile Thr Lys 
    1115                 1120                 1125             


Asp Phe  Pro Gln Tyr Phe Ala  Val Val Ser Arg Ile  Lys Gln Glu 
    1130                 1135                 1140             


Ser Asn  Gln Ile Gly Pro Glu  Gly Gly Ile Leu Ser  Ser Thr Thr 
    1145                 1150                 1155             


Val Pro  Leu Val Gln Ala Ser  Phe Pro Glu Gly Ala  Leu Thr Lys 
    1160                 1165                 1170             


Arg Ile  Arg Val Gly Leu Gln  Ala Gln Pro Val Pro  Asp Glu Ile 
    1175                 1180                 1185             


Val Lys  Lys Ile Leu Gly Asn  Lys Ala Thr Phe Ser  Pro Ile Val 
    1190                 1195                 1200             


Thr Val  Glu Pro Arg Arg Arg  Lys Phe His Lys Pro  Ile Thr Met 
    1205                 1210                 1215             


Thr Ile  Pro Val Pro Pro Pro  Ser Gly Glu Gly Val  Ser Asn Gly 
    1220                 1225                 1230             


Tyr Lys  Gly Asp Thr Thr Pro  Asn Leu Arg Leu Leu  Cys Ser Ile 
    1235                 1240                 1245             


Thr Gly  Gly Thr Ser Pro Ala  Gln Trp Glu Asp Ile  Thr Gly Thr 
    1250                 1255                 1260             


Thr Pro  Leu Thr Phe Ile Lys  Asp Cys Val Ser Phe  Thr Thr Asn 
    1265                 1270                 1275             


Val Ser  Ala Arg Phe Trp Leu  Ala Asp Cys His Gln  Val Leu Glu 
    1280                 1285                 1290             


Thr Val  Gly Leu Ala Thr Gln  Leu Tyr Arg Glu Leu  Ile Cys Val 
    1295                 1300                 1305             


Pro Tyr  Met Ala Lys Phe Val  Val Phe Ala Lys Met  Asn Asp Pro 
    1310                 1315                 1320             


Val Glu  Ser Ser Leu Arg Cys  Phe Cys Met Thr Asp  Asp Lys Val 
    1325                 1330                 1335             


Asp Lys  Thr Leu Glu Gln Gln  Glu Asn Phe Glu Glu  Val Ala Arg 
    1340                 1345                 1350             


Ser Lys  Asp Ile Glu Val Leu  Glu Gly Lys Pro Ile  Tyr Val Asp 
    1355                 1360                 1365             


Cys Tyr  Gly Asn Leu Ala Pro  Leu Thr Lys Gly Gly  Gln Gln Leu 
    1370                 1375                 1380             


Val Phe  Asn Phe Tyr Ser Phe  Lys Glu Asn Arg Leu  Pro Phe Ser 
    1385                 1390                 1395             


Ile Lys  Ile Arg Asp Thr Ser  Gln Glu Pro Cys Gly  Arg Leu Ser 
    1400                 1405                 1410             


Phe Leu  Lys Glu Pro Lys Thr  Thr Lys Gly Leu Pro  Gln Thr Ala 
    1415                 1420                 1425             


Val Cys  Asn Leu Asn Ile Thr  Leu Pro Ala His Lys  Lys Glu Thr 
    1430                 1435                 1440             


Glu Ser  Asp Gln Asp Asp Glu  Ile Glu Lys Thr Asp  Arg Arg Gln 
    1445                 1450                 1455             


Ser Phe  Ala Ser Leu Ala Leu  Arg Lys Arg Tyr Ser  Tyr Leu Thr 
    1460                 1465                 1470             


Glu Pro  Gly Met Ile Glu Arg  Ser Thr Gly Ala Thr  Arg Ser Leu 
    1475                 1480                 1485             


Pro Thr  Thr Tyr Ser Tyr Lys  Pro Phe Phe Ser Thr  Arg Pro Tyr 
    1490                 1495                 1500             


Gln Ser  Trp Thr Thr Ala Pro  Ile Thr Val Pro Gly  Pro Ala Lys 
    1505                 1510                 1515             


Ser Gly  Phe Thr Ser Leu Ser  Ser Ser Ser Ser Asn  Thr Pro Ser 
    1520                 1525                 1530             


Ala Ser  Pro Leu Lys Ser Ile  Trp Ser Val Ser Thr  Pro Ser Pro 
    1535                 1540                 1545             


Ile Lys  Ser Thr Leu Gly Ala  Ser Thr Thr Ser Ser  Val Lys Ser 
    1550                 1555                 1560             


Ile Ser  Asp Val Ala Ser Pro  Ile Arg Ser Phe Arg  Thr Met Ser 
    1565                 1570                 1575             


Ser Pro  Ile Lys Thr Val Val  Ser Gln Ser Pro Tyr  Asn Ile Gln 
    1580                 1585                 1590             


Val Ser  Ser Gly Thr Leu Ala  Arg Ala Pro Ala Val  Thr Glu Ala 
    1595                 1600                 1605             


Thr Pro  Leu Lys Gly Leu Ala  Ser Asn Ser Thr Phe  Ser Ser Arg 
    1610                 1615                 1620             


Thr Ser  Pro Val Thr Thr Ala  Gly Ser Leu Leu Glu  Arg Ser Ser 
    1625                 1630                 1635             


Ile Thr  Met Thr Pro Pro Ala  Ser Pro Lys Ser Asn  Ile Asn Met 
    1640                 1645                 1650             


Tyr Ser  Ser Ser Leu Pro Phe  Lys Ser Ile Ile Thr  Ser Ala Ala 
    1655                 1660                 1665             


Pro Leu  Ile Ser Ser Pro Leu  Lys Ser Val Val Ser  Pro Val Lys 
    1670                 1675                 1680             


Ser Ala  Val Asp Val Ile Ser  Ser Ala Lys Ile Thr  Met Ala Ser 
    1685                 1690                 1695             


Ser Leu  Ser Ser Pro Val Lys  Gln Met Pro Gly His  Ala Glu Val 
    1700                 1705                 1710             


Ala Leu  Val Asn Gly Ser Ile  Ser Pro Leu Lys Tyr  Pro Ser Ser 
    1715                 1720                 1725             


Ser Thr  Leu Ile Asn Gly Cys  Lys Ala Thr Ala Thr  Leu Gln Glu 
    1730                 1735                 1740             


Lys Ile  Ser Ser Ala Thr Asn  Ser Val Ser Ser Val  Val Ser Ala 
    1745                 1750                 1755             


Ala Thr  Asp Thr Val Glu Lys  Val Phe Ser Thr Thr  Thr Ala Met 
    1760                 1765                 1770             


Pro Phe  Ser Pro Leu Arg Ser  Tyr Val Ser Ala Ala  Pro Ser Ala 
    1775                 1780                 1785             


Phe Gln  Ser Leu Arg Thr Pro  Ser Ala Ser Ala Leu  Tyr Thr Ser 
    1790                 1795                 1800             


Leu Gly  Ser Ser Ile Ser Ala  Thr Thr Ser Ser Val  Thr Ser Ser 
    1805                 1810                 1815             


Ile Ile  Thr Val Pro Val Tyr  Ser Val Val Asn Val  Leu Pro Glu 
    1820                 1825                 1830             


Pro Ala  Leu Lys Lys Leu Pro  Asp Ser Asn Ser Phe  Thr Lys Ser 
    1835                 1840                 1845             


Ala Ala  Ala Leu Leu Ser Pro  Ile Lys Thr Leu Thr  Thr Glu Thr 
    1850                 1855                 1860             


His Pro  Gln Pro His Phe Ser  Arg Thr Ser Ser Pro  Val Lys Ser 
    1865                 1870                 1875             


Ser Leu  Phe Leu Ala Pro Ser  Ala Leu Lys Leu Ser  Thr Pro Ser 
    1880                 1885                 1890             


Ser Leu  Ser Ser Ser Gln Glu  Ile Leu Lys Asp Val  Ala Glu Met 
    1895                 1900                 1905             


Lys Glu  Asp Leu Met Arg Met  Thr Ala Ile Leu Gln  Thr Asp Val 
    1910                 1915                 1920             


Pro Glu  Glu Lys Pro Phe Gln  Pro Glu Leu Pro Lys  Glu Gly Arg 
    1925                 1930                 1935             


Ile Asp  Asp Glu Glu Pro Phe  Lys Ile Val Glu Lys  Val Lys Glu 
    1940                 1945                 1950             


Asp Leu  Val Lys Val Ser Glu  Ile Leu Lys Lys Asp  Val Cys Val 
    1955                 1960                 1965             


Asp Asn  Lys Gly Ser Pro Lys  Ser Pro Lys Ser Asp  Lys Gly His 
    1970                 1975                 1980             


Ser Pro  Glu Asp Asp Trp Ile  Glu Phe Ser Ser Glu  Glu Ile Arg 
    1985                 1990                 1995             


Glu Ala  Arg Gln Gln Ala Ala  Ala Ser Gln Ser Pro  Ser Leu Pro 
    2000                 2005                 2010             


Glu Arg  Val Gln Val Lys Ala  Lys Ala Ala Ser Glu  Lys Asp Tyr 
    2015                 2020                 2025             


Asn Leu  Thr Lys Val Ile Asp  Tyr Leu Thr Asn Asp  Ile Gly Ser 
    2030                 2035                 2040             


Ser Ser  Leu Thr Asn Leu Lys  Tyr Lys Phe Glu Asp  Ala Lys Lys 
    2045                 2050                 2055             


Asp Gly  Glu Glu Arg Gln Lys  Arg Val Leu Lys Pro  Ala Ile Ala 
    2060                 2065                 2070             


Leu Gln  Glu His Lys Leu Lys  Met Pro Pro Ala Ser  Met Arg Thr 
    2075                 2080                 2085             


Ser Thr  Ser Glu Lys Glu Leu  Cys Lys Met Ala Asp  Ser Phe Phe 
    2090                 2095                 2100             


Gly Thr  Asp Thr Ile Leu Glu  Ser Pro Asp Asp Phe  Ser Gln His 
    2105                 2110                 2115             


Asp Gln  Asp Lys Ser Pro Leu  Ser Asp Ser Gly Phe  Glu Thr Arg 
    2120                 2125                 2130             


Ser Glu  Lys Thr Pro Ser Ala  Pro Gln Ser Ala Glu  Ser Thr Gly 
    2135                 2140                 2145             


Pro Lys  Pro Leu Phe His Glu  Val Pro Ile Pro Pro  Val Ile Thr 
    2150                 2155                 2160             


Glu Thr  Arg Thr Glu Val Val  His Val Ile Arg Ser  Tyr Asp Pro 
    2165                 2170                 2175             


Ser Ala  Gly Asp Val Pro Gln  Thr Gln Pro Glu Glu  Pro Val Ser 
    2180                 2185                 2190             


Pro Lys  Pro Ser Pro Thr Phe  Met Glu Leu Glu Pro  Lys Pro Thr 
    2195                 2200                 2205             


Thr Ser  Ser Ile Lys Glu Lys  Val Lys Ala Phe Gln  Met Lys Ala 
    2210                 2215                 2220             


Ser Ser  Glu Glu Asp Asp His  Asn Arg Val Leu Ser  Lys Gly Met 
    2225                 2230                 2235             


Arg Val  Lys Glu Glu Thr His  Ile Thr Thr Thr Thr  Arg Met Val 
    2240                 2245                 2250             


Tyr His  Ser Pro Pro Gly Gly  Glu Gly Ala Ser Glu  Arg Ile Glu 
    2255                 2260                 2265             


Glu Thr  Met Ser Val His Asp  Ile Met Lys Ala Phe  Gln Ser Gly 
    2270                 2275                 2280             


Arg Asp  Pro Ser Lys Glu Leu  Ala Gly Leu Phe Glu  His Lys Ser 
    2285                 2290                 2295             


Ala Val  Ser Pro Asp Val His  Lys Ser Ala Ala Glu  Thr Ser Ala 
    2300                 2305                 2310             


Gln His  Ala Glu Lys Asp Asn  Gln Met Lys Pro Lys  Leu Glu Arg 
    2315                 2320                 2325             


Ile Ile  Glu Val His Ile Glu  Lys Gly Asn Gln Ala  Glu Pro Thr 
    2330                 2335                 2340             


Glu Val  Ile Ile Arg Glu Thr  Lys Lys His Pro Glu  Lys Glu Met 
    2345                 2350                 2355             


Tyr Val  Tyr Gln Lys Asp Leu  Ser Arg Gly Asp Ile  Asn Leu Lys 
    2360                 2365                 2370             


Asp Phe  Leu Pro Glu Lys His  Asp Ala Phe Pro Cys  Ser Glu Glu 
    2375                 2380                 2385             


Gln Gly  Gln Gln Glu Glu Glu  Glu Leu Thr Ala Glu  Glu Ser Leu 
    2390                 2395                 2400             


Pro Ser  Tyr Leu Glu Ser Ser  Arg Val Asn Thr Pro  Val Ser Gln 
    2405                 2410                 2415             


Glu Glu  Asp Ser Arg Pro Ser  Ser Ala Gln Leu Ile  Ser Asp Asp 
    2420                 2425                 2430             


Ser Tyr  Lys Thr Leu Lys Leu  Leu Ser Gln His Ser  Ile Glu Tyr 
    2435                 2440                 2445             


His Asp  Asp Glu Leu Ser Glu  Leu Arg Gly Glu Ser  Tyr Arg Phe 
    2450                 2455                 2460             


Ala Glu  Lys Met Leu Leu Ser  Glu Lys Leu Asp Val  Ser His Ser 
    2465                 2470                 2475             


Asp Thr  Glu Glu Ser Val Thr  Asp His Ala Gly Pro  Pro Ser Ser 
    2480                 2485                 2490             


Glu Leu  Gln Gly Ser Asp Lys  Arg Ser Arg Glu Lys  Ile Ala Thr 
    2495                 2500                 2505             


Ala Pro  Lys Lys Glu Ile Leu  Ser Lys Ile Tyr Lys  Asp Val Ser 
    2510                 2515                 2520             


Glu Asn  Gly Val Gly Lys Val  Ser Lys Asp Glu His  Phe Asp Lys 
    2525                 2530                 2535             


Val Thr  Val Leu His Tyr Ser  Gly Asn Val Ser Ser  Pro Lys His 
    2540                 2545                 2550             


Ala Met  Trp Met Arg Phe Thr  Glu Asp Arg Leu Asp  Arg Gly Arg 
    2555                 2560                 2565             


Glu Lys  Leu Ile Tyr Glu Asp  Arg Val Asp Arg Thr  Val Lys Glu 
    2570                 2575                 2580             


Ala Glu  Glu Lys Leu Thr Glu  Val Ser Gln Phe Phe  Arg Asp Lys 
    2585                 2590                 2595             


Thr Glu  Lys Leu Asn Asp Glu  Leu Gln Ser Pro Glu  Lys Lys Ala 
    2600                 2605                 2610             


Arg Pro  Lys Asn Gly Lys Glu  Tyr Ser Ser Gln Ser  Pro Thr Ser 
    2615                 2620                 2625             


Ser Ser  Pro Glu Lys Val Leu  Leu Thr Glu Leu Leu  Ala Ser Asn 
    2630                 2635                 2640             


Asp Glu  Trp Val Lys Ala Arg  Gln His Gly Pro Asp  Gly Gln Gly 
    2645                 2650                 2655             


Phe Pro  Lys Ala Glu Glu Lys  Ala Pro Ser Leu Pro  Ser Ser Pro 
    2660                 2665                 2670             


Glu Lys  Met Val Leu Ser Gln  Gln Thr Glu Asp Ser  Lys Ser Thr 
    2675                 2680                 2685             


Val Glu  Ala Lys Gly Ser Ile  Ser Gln Ser Lys Ala  Pro Asp Gly 
    2690                 2695                 2700             


Pro Gln  Ser Gly Phe Gln Leu  Lys Gln Ser Lys Leu  Ser Ser Ile 
    2705                 2710                 2715             


Arg Leu  Lys Phe Glu Gln Gly  Thr His Ala Lys Ser  Lys Asp Met 
    2720                 2725                 2730             


Ser Gln  Glu Asp Arg Lys Ser  Asp Gly Gln Ser Arg  Ile Pro Val 
    2735                 2740                 2745             


Lys Lys  Ile Gln Glu Ser Lys  Leu Pro Val Tyr Gln  Val Phe Ala 
    2750                 2755                 2760             


Arg Glu  Lys Gln Gln Lys Ala  Ile Asp Leu Pro Asp  Glu Ser Val 
    2765                 2770                 2775             


Ser Val  Gln Lys Asp Phe Met  Val Leu Lys Thr Lys  Asp Glu His 
    2780                 2785                 2790             


Ala Gln  Ser Asn Glu Ile Val  Val Asn Asp Ser Gly  Ser Asp Asn 
    2795                 2800                 2805             


Val Lys  Lys Gln Arg Thr Glu  Met Ser Ser Lys Ala  Met Pro Asp 
    2810                 2815                 2820             


Ser Phe  Ser Glu Gln Gln Ala  Lys Asp Leu Ala Cys  His Ile Thr 
    2825                 2830                 2835             


Ser Asp  Leu Ala Thr Arg Gly  Pro Trp Asp Lys Lys  Val Phe Arg 
    2840                 2845                 2850             


Thr Trp  Glu Ser Ser Gly Ala  Thr Asn Asn Lys Ser  Gln Lys Glu 
    2855                 2860                 2865             


Lys Leu  Ser His Val Leu Val  His Asp Val Arg Glu  Asn His Ile 
    2870                 2875                 2880             


Gly His  Pro Glu Ser Lys Ser  Val Asp Gln Lys Asn  Glu Phe Met 
    2885                 2890                 2895             


Ser Val  Thr Glu Arg Glu Arg  Lys Leu Leu Thr Asn  Gly Ser Leu 
    2900                 2905                 2910             


Ser Glu  Ile Lys Glu Met Thr  Val Lys Ser Pro Ser  Lys Lys Val 
    2915                 2920                 2925             


Leu Tyr  Arg Glu Tyr Val Val  Lys Glu Gly Asp His  Pro Gly Gly 
    2930                 2935                 2940             


Leu Leu  Asp Gln Pro Ser Arg  Arg Ser Glu Ser Ser  Ala Val Ser 
    2945                 2950                 2955             


His Ile  Pro Val Arg Val Ala  Asp Glu Arg Arg Met  Leu Ser Ser 
    2960                 2965                 2970             


Asn Ile  Pro Asp Gly Phe Cys  Glu Gln Ser Ala Phe  Pro Lys His 
    2975                 2980                 2985             


Glu Leu  Ser Gln Lys Leu Ser  Gln Ser Ser Met Ser  Lys Glu Thr 
    2990                 2995                 3000             


Val Glu  Thr Gln His Phe Asn  Ser Ile Glu Asp Glu  Lys Val Thr 
    3005                 3010                 3015             


Tyr Ser  Glu Ile Ser Lys Val  Ser Lys His Gln Ser  Tyr Val Gly 
    3020                 3025                 3030             


Leu Cys  Pro Pro Leu Glu Glu  Thr Glu Thr Ser Pro  Thr Lys Ser 
    3035                 3040                 3045             


Pro Asp  Ser Leu Glu Phe Ser  Pro Gly Lys Glu Ser  Pro Ser Ser 
    3050                 3055                 3060             


Asp Val  Phe Asp His Ser Pro  Ile Asp Gly Leu Glu  Lys Leu Ala 
    3065                 3070                 3075             


Pro Leu  Ala Gln Thr Glu Gly  Gly Lys Glu Ile Lys  Thr Leu Pro 
    3080                 3085                 3090             


Val Tyr  Val Ser Phe Val Gln  Val Gly Lys Gln Tyr  Glu Lys Glu 
    3095                 3100                 3105             


Ile Gln  Gln Gly Gly Val Lys  Lys Ile Ile Ser Gln  Glu Cys Lys 
    3110                 3115                 3120             


Thr Val  Gln Glu Thr Arg Gly  Thr Phe Tyr Thr Thr  Arg Gln Gln 
    3125                 3130                 3135             


Lys Gln  Pro Pro Ser Pro Gln  Gly Ser Pro Glu Asp  Asp Thr Leu 
    3140                 3145                 3150             


Glu Gln  Val Ser Phe Leu Asp  Ser Ser Gly Lys Ser  Pro Leu Thr 
    3155                 3160                 3165             


Pro Glu  Thr Pro Ser Ser Glu  Glu Val Ser Tyr Glu  Phe Thr Ser 
    3170                 3175                 3180             


Lys Thr  Pro Asp Ser Leu Ile  Ala Tyr Ile Pro Gly  Lys Pro Ser 
    3185                 3190                 3195             


Pro Ile  Pro Glu Val Ser Glu  Glu Ser Glu Glu Glu  Glu Gln Ala 
    3200                 3205                 3210             


Lys Ser  Thr Ser Leu Lys Gln  Thr Thr Val Glu Glu  Thr Ala Val 
    3215                 3220                 3225             


Glu Arg  Glu Met Pro Asn Asp  Val Ser Lys Asp Ser  Asn Gln Arg 
    3230                 3235                 3240             


Pro Lys  Asn Asn Arg Val Ala  Tyr Ile Glu Phe Pro  Pro Pro Pro 
    3245                 3250                 3255             


Pro Leu  Asp Ala Asp Gln Ile  Glu Ser Asp Lys Lys  His His Tyr 
    3260                 3265                 3270             


Leu Pro  Glu Lys Glu Val Asp  Met Ile Glu Val Asn  Leu Gln Asp 
    3275                 3280                 3285             


Glu His  Asp Lys Tyr Gln Leu  Ala Glu Pro Val Ile  Arg Val Gln 
    3290                 3295                 3300             


Pro Pro  Ser Pro Val Pro Pro  Gly Ala Asp Val Ser  Asp Ser Ser 
    3305                 3310                 3315             


Asp Asp  Glu Ser Ile Tyr Gln  Pro Val Pro Val Lys  Lys Tyr Thr 
    3320                 3325                 3330             


Phe Lys  Leu Lys Glu Val Asp  Asp Glu Gln Lys Glu  Lys Pro Lys 
    3335                 3340                 3345             


Ala Ser  Ala Glu Lys Ala Ser  Asn Gln Lys Glu Leu  Glu Ser Asn 
    3350                 3355                 3360             


Gly Ser  Gly Lys Asp Asn Glu  Phe Gly Leu Gly Leu  Asp Ser Pro 
    3365                 3370                 3375             


Gln Asn  Glu Ile Ala Gln Asn  Gly Asn Asn Asp Gln  Ser Ile Thr 
    3380                 3385                 3390             


Glu Cys  Ser Ile Ala Thr Thr  Ala Glu Phe Ser His  Asp Thr Asp 
    3395                 3400                 3405             


Ala Thr  Glu Ile Asp Ser Leu  Asp Gly Tyr Asp Leu  Gln Asp Glu 
    3410                 3415                 3420             


Asp Asp  Gly Leu Thr Glu Ser  Asp Ser Lys Leu Pro  Ile Gln Ala 
    3425                 3430                 3435             


Met Glu  Ile Lys Lys Asp Ile  Trp Asn Thr Glu Gly  Ile Leu Lys 
    3440                 3445                 3450             


Pro Ala  Asp Arg Ser Phe Ser  Gln Ser Lys Leu Glu  Val Ile Glu 
    3455                 3460                 3465             


Glu Glu  Gly Lys Val Gly Pro  Asp Glu Asp Lys Pro  Pro Ser Lys 
    3470                 3475                 3480             


Ser Ser  Ser Ser Glu Lys Thr  Pro Asp Lys Thr Asp  Gln Lys Ser 
    3485                 3490                 3495             


Gly Ala  Gln Phe Phe Thr Leu  Glu Gly Arg His Pro  Asp Arg Ser 
    3500                 3505                 3510             


Val Phe  Pro Asp Thr Tyr Phe  Ser Tyr Lys Val Asp  Glu Glu Phe 
    3515                 3520                 3525             


Ala Thr  Pro Phe Lys Thr Val  Ala Thr Lys Gly Leu  Asp Phe Asp 
    3530                 3535                 3540             


Pro Trp  Ser Asn Asn Arg Gly  Asp Asp Glu Val Phe  Asp Ser Lys 
    3545                 3550                 3555             


Ser Arg  Glu Asp Glu Thr Lys  Pro Phe Gly Leu Ala  Val Glu Asp 
    3560                 3565                 3570             


Arg Ser  Pro Ala Thr Thr Pro  Asp Thr Thr Pro Ala  Arg Thr Pro 
    3575                 3580                 3585             


Thr Asp  Glu Ser Thr Pro Thr  Ser Glu Pro Asn Pro  Phe Pro Phe 
    3590                 3595                 3600             


His Glu  Gly Lys Met Phe Glu  Met Thr Arg Ser Gly  Ala Ile Asp 
    3605                 3610                 3615             


Met Ser  Lys Arg Asp Phe Val  Glu Glu Arg Leu Gln  Phe Phe Gln 
    3620                 3625                 3630             


Ile Gly  Glu His Thr Ser Glu  Gly Lys Ser Gly Asp  Gln Gly Glu 
    3635                 3640                 3645             


Gly Asp  Lys Ser Met Val Thr  Ala Thr Pro Gln Pro  Gln Ser Gly 
    3650                 3655                 3660             


Asp Thr  Thr Val Glu Thr Asn  Leu Glu Arg Asn Val  Glu Thr Pro 
    3665                 3670                 3675             


Thr Val  Glu Pro Asn Pro Ser  Ile Pro Thr Ser Gly  Glu Cys Gln 
    3680                 3685                 3690             


Glu Gly  Thr Ser Ser Ser Gly  Ser Leu Glu Lys Ser  Ala Ala Ala 
    3695                 3700                 3705             


Thr Asn  Thr Ser Lys Val Asp  Pro Lys Leu Arg Thr  Pro Ile Lys 
    3710                 3715                 3720             


Met Gly  Ile Ser Ala Ser Thr  Met Thr Met Lys Lys  Glu Gly Pro 
    3725                 3730                 3735             


Gly Glu  Ile Thr Asp Lys Ile  Glu Ala Val Met Thr  Ser Cys Gln 
    3740                 3745                 3750             


Gly Leu  Glu Asn Glu Thr Ile  Thr Met Ile Ser Asn  Thr Ala Asn 
    3755                 3760                 3765             


Ser Gln  Met Gly Val Arg Pro  His Glu Lys His Asp  Phe Gln Lys 
    3770                 3775                 3780             


Asp Asn  Phe Asn Asn Asn Asn  Asn Leu Asp Ser Ser  Thr Ile Gln 
    3785                 3790                 3795             


Thr Asp  Asn Ile Met Ser Asn  Ile Val Leu Thr Glu  His Ser Ala 
    3800                 3805                 3810             


Pro Thr  Cys Thr Thr Glu Lys  Asp Asn Pro Val Lys  Val Ser Ser 
    3815                 3820                 3825             


Gly Lys  Lys Thr Gly Val Leu  Gln Gly His Cys Val  Arg Asp Lys 
    3830                 3835                 3840             


Gln Lys  Val Leu Gly Glu Gln  Gln Lys Thr Lys Glu  Leu Ile Gly 
    3845                 3850                 3855             


Ile Arg  Gln Lys Ser Lys Leu  Pro Ile Lys Ala Thr  Ser Pro Lys 
    3860                 3865                 3870             


Asp Thr  Phe Pro Pro Asn His  Met Ser Asn Thr Lys  Ala Ser Lys 
    3875                 3880                 3885             


Met Lys  Gln Val Ser Gln Ser  Glu Lys Thr Lys Ala  Leu Thr Thr 
    3890                 3895                 3900             


Ser Ser  Cys Val Asp Val Lys  Ser Arg Ile Pro Val  Lys Asn Thr 
    3905                 3910                 3915             


His Arg  Asp Asn Ile Ile Ala  Val Arg Lys Ala Cys  Ala Thr Gln 
    3920                 3925                 3930             


Lys Gln  Gly Gln Pro Glu Lys  Gly Lys Ala Lys Gln  Leu Pro Ser 
    3935                 3940                 3945             


Lys Leu  Pro Val Lys Val Arg  Ser Thr Cys Val Thr  Thr Thr Thr 
    3950                 3955                 3960             


Thr Thr  Ala Thr Thr Thr Thr  Thr Thr Thr Thr Thr  Thr Thr Thr 
    3965                 3970                 3975             


Ser Cys  Thr Val Lys Val Arg  Lys Ser Gln Leu Lys  Glu Val Cys 
    3980                 3985                 3990             


Lys His  Ser Ile Glu Tyr Phe  Lys Gly Ile Ser Gly  Glu Thr Leu 
    3995                 4000                 4005             


Lys Leu  Val Asp Arg Leu Ser  Glu Glu Glu Lys Lys  Met Gln Ser 
    4010                 4015                 4020             


Glu Leu  Ser Asp Glu Glu Glu  Ser Thr Ser Arg Asn  Thr Ser Leu 
    4025                 4030                 4035             


Ser Glu  Thr Ser Arg Gly Gly  Gln Pro Ser Val Thr  Thr Lys Ser 
    4040                 4045                 4050             


Ala Arg  Asp Lys Lys Thr Glu  Ala Ala Pro Leu Lys  Ser Lys Ser 
    4055                 4060                 4065             


Glu Lys  Ala Gly Ser Glu Lys  Arg Ser Ser Arg Arg  Thr Gly Pro 
    4070                 4075                 4080             


Gln Ser  Pro Cys Glu Arg Thr  Asp Ile Arg Met Ala  Ile Val Ala 
    4085                 4090                 4095             


Asp His  Leu Gly Leu Ser Trp  Thr Glu Leu Ala Arg  Glu Leu Asn 
    4100                 4105                 4110             


Phe Ser  Val Asp Glu Ile Asn  Gln Ile Arg Val Glu  Asn Pro Asn 
    4115                 4120                 4125             


Ser Leu  Ile Ser Gln Ser Phe  Met Leu Leu Lys Lys  Trp Val Thr 
    4130                 4135                 4140             


Arg Asp  Gly Lys Asn Ala Thr  Thr Asp Ala Leu Thr  Ser Val Leu 
    4145                 4150                 4155             


Thr Lys  Ile Asn Arg Ile Asp  Ile Val Thr Leu Leu  Glu Gly Pro 
    4160                 4165                 4170             


Ile Phe  Asp Tyr Gly Asn Ile  Ser Gly Thr Arg Ser  Phe Ala Asp 
    4175                 4180                 4185             


Glu Asn  Asn Val Phe His Asp  Pro Val Asp Gly Trp  Gln Asn Glu 
    4190                 4195                 4200             


Thr Ser  Ser Gly Asn Leu Glu  Ser Cys Ala Gln Ala  Arg Arg Val 
    4205                 4210                 4215             


Thr Gly  Gly Leu Leu Asp Arg  Leu Asp Asp Ser Pro  Asp Gln Cys 
    4220                 4225                 4230             


Arg Asp  Ser Ile Thr Ser Tyr  Leu Lys Gly Glu Ala  Gly Lys Phe 
    4235                 4240                 4245             


Glu Ala  Asn Gly Ser His Thr  Glu Ile Thr Pro Glu  Ala Lys Thr 
    4250                 4255                 4260             


Lys Ser  Tyr Phe Pro Glu Ser  Gln Asn Asp Val Gly  Lys Gln Ser 
    4265                 4270                 4275             


Thr Lys  Glu Thr Leu Lys Pro  Lys Ile His Gly Ser  Gly His Val 
    4280                 4285                 4290             


Glu Glu  Pro Ala Ser Pro Leu  Ala Ala Tyr Gln Lys  Ser Leu Glu 
    4295                 4300                 4305             


Glu Thr  Ser Lys Leu Ile Ile  Glu Glu Thr Lys Pro  Cys Val Pro 
    4310                 4315                 4320             


Val Ser  Met Lys Lys Met Ser  Arg Thr Ser Pro Ala  Asp Gly Lys 
    4325                 4330                 4335             


Pro Arg  Leu Ser Leu His Glu  Glu Glu Gly Ser Ser  Gly Ser Glu 
    4340                 4345                 4350             


Gln Lys  Gln Gly Glu Gly Phe  Lys Val Lys Thr Lys  Lys Glu Ile 
    4355                 4360                 4365             


Arg His  Val Glu Lys Lys Ser  His Ser 
    4370                 4375         


<210>  3152
<211>  1303
<212>  PRT
<213>  homo sapiens

<400>  3152

Met Glu Ala Ala Pro Gly Thr Pro Pro Pro Pro Pro Ser Glu Ser Pro 
1               5                   10                  15      


Pro Pro Pro Ser Pro Pro Pro Pro Ser Thr Pro Ser Pro Pro Pro Cys 
            20                  25                  30          


Ser Pro Asp Ala Arg Pro Ala Thr Pro His Leu Leu His His Arg Leu 
        35                  40                  45              


Pro Leu Pro Asp Asp Arg Glu Asp Gly Glu Leu Glu Glu Gly Glu Leu 
    50                  55                  60                  


Glu Asp Asp Gly Ala Glu Glu Thr Gln Asp Thr Ser Gly Gly Pro Glu 
65                  70                  75                  80  


Arg Ser Arg Lys Glu Lys Gly Glu Lys His His Ser Asp Ser Asp Glu 
                85                  90                  95      


Glu Lys Ser His Arg Arg Leu Lys Arg Lys Arg Lys Lys Glu Arg Glu 
            100                 105                 110         


Lys Glu Lys Arg Arg Ser Lys Lys Arg Arg Lys Ser Lys His Lys Arg 
        115                 120                 125             


His Ala Ser Ser Ser Asp Asp Phe Ser Asp Phe Ser Asp Asp Ser Asp 
    130                 135                 140                 


Phe Ser Pro Ser Glu Lys Gly His Arg Lys Tyr Arg Glu Tyr Ser Pro 
145                 150                 155                 160 


Pro Tyr Ala Pro Ser His Gln Gln Tyr Pro Pro Ser His Ala Thr Pro 
                165                 170                 175     


Leu Pro Lys Lys Ala Tyr Ser Lys Met Asp Ser Lys Ser Tyr Gly Met 
            180                 185                 190         


Tyr Glu Asp Tyr Glu Asn Glu Gln Tyr Gly Glu Tyr Glu Gly Asp Glu 
        195                 200                 205             


Glu Glu Asp Met Gly Lys Glu Asp Tyr Asp Asp Phe Thr Lys Glu Leu 
    210                 215                 220                 


Asn Gln Tyr Arg Arg Ala Lys Glu Gly Ser Ser Arg Gly Arg Gly Ser 
225                 230                 235                 240 


Arg Gly Arg Gly Arg Gly Tyr Arg Gly Arg Gly Ser Arg Gly Gly Ser 
                245                 250                 255     


Arg Gly Arg Gly Met Gly Arg Gly Ser Arg Gly Arg Gly Arg Gly Ser 
            260                 265                 270         


Met Gly Gly Asp His Pro Glu Asp Glu Glu Asp Phe Tyr Glu Glu Glu 
        275                 280                 285             


Met Asp Tyr Gly Glu Ser Glu Glu Pro Met Gly Asp Asp Asp Tyr Asp 
    290                 295                 300                 


Glu Tyr Ser Lys Glu Leu Asn Gln Tyr Arg Arg Ser Lys Asp Ser Arg 
305                 310                 315                 320 


Gly Arg Gly Leu Ser Arg Gly Arg Gly Arg Gly Ser Arg Gly Arg Gly 
                325                 330                 335     


Lys Gly Met Gly Arg Gly Arg Gly Arg Gly Gly Ser Arg Gly Gly Met 
            340                 345                 350         


Asn Lys Gly Gly Met Asn Asp Asp Glu Asp Phe Tyr Asp Glu Asp Met 
        355                 360                 365             


Gly Asp Gly Gly Gly Gly Ser Tyr Arg Ser Arg Asp His Asp Lys Pro 
    370                 375                 380                 


His Gln Gln Ser Asp Lys Lys Gly Lys Val Ile Cys Lys Tyr Phe Val 
385                 390                 395                 400 


Glu Gly Arg Cys Thr Trp Gly Asp His Cys Asn Phe Ser His Asp Ile 
                405                 410                 415     


Glu Leu Pro Lys Lys Arg Glu Leu Cys Lys Phe Tyr Ile Thr Gly Phe 
            420                 425                 430         


Cys Ala Arg Ala Glu Asn Cys Pro Tyr Met His Gly Asp Phe Pro Cys 
        435                 440                 445             


Lys Leu Tyr His Thr Thr Gly Asn Cys Ile Asn Gly Asp Asp Cys Met 
    450                 455                 460                 


Phe Ser His Asp Pro Leu Thr Glu Glu Thr Arg Glu Leu Leu Asp Lys 
465                 470                 475                 480 


Met Leu Ala Asp Asp Ala Glu Ala Gly Ala Glu Asp Glu Lys Glu Val 
                485                 490                 495     


Glu Glu Leu Lys Lys Gln Gly Ile Asn Pro Leu Pro Lys Pro Pro Pro 
            500                 505                 510         


Gly Val Gly Leu Leu Pro Thr Pro Pro Arg Pro Pro Gly Pro Gln Ala 
        515                 520                 525             


Pro Thr Ser Pro Asn Gly Arg Pro Met Gln Gly Gly Pro Pro Pro Pro 
    530                 535                 540                 


Pro Pro Pro Pro Pro Pro Pro Pro Gly Pro Pro Gln Met Pro Met Pro 
545                 550                 555                 560 


Val His Glu Pro Leu Ser Pro Gln Gln Leu Gln Gln Gln Asp Met Tyr 
                565                 570                 575     


Asn Lys Lys Ile Pro Ser Leu Phe Glu Ile Val Val Arg Pro Thr Gly 
            580                 585                 590         


Gln Leu Ala Glu Lys Leu Gly Val Arg Phe Pro Gly Pro Gly Gly Pro 
        595                 600                 605             


Pro Gly Pro Met Gly Pro Gly Pro Asn Met Gly Pro Pro Gly Pro Met 
    610                 615                 620                 


Gly Gly Pro Met His Pro Asp Met His Pro Asp Met His Pro Asp Met 
625                 630                 635                 640 


His Pro Asp Met His Ala Asp Met His Ala Asp Met Pro Met Gly Pro 
                645                 650                 655     


Gly Met Asn Pro Gly Pro Pro Met Gly Pro Gly Gly Pro Pro Met Met 
            660                 665                 670         


Pro Tyr Gly Pro Gly Asp Ser Pro His Ser Gly Met Met Pro Pro Ile 
        675                 680                 685             


Pro Pro Ala Gln Asn Phe Tyr Glu Asn Phe Tyr Gln Gln Gln Glu Gly 
    690                 695                 700                 


Met Glu Met Glu Pro Gly Leu Leu Gly Asp Ala Glu Asp Tyr Gly His 
705                 710                 715                 720 


Tyr Glu Glu Leu Pro Gly Glu Pro Gly Glu His Leu Phe Pro Glu His 
                725                 730                 735     


Pro Leu Glu Pro Asp Ser Phe Ser Glu Gly Gly Pro Pro Gly Arg Pro 
            740                 745                 750         


Lys Pro Gly Ala Gly Val Pro Asp Phe Leu Pro Ser Ala Gln Arg Ala 
        755                 760                 765             


Leu Tyr Leu Arg Ile Gln Gln Lys Gln Gln Glu Glu Glu Glu Arg Ala 
    770                 775                 780                 


Arg Arg Leu Ala Glu Ser Ser Lys Gln Asp Arg Glu Asn Glu Glu Gly 
785                 790                 795                 800 


Asp Thr Gly Asn Trp Tyr Ser Ser Asp Glu Asp Glu Gly Gly Ser Ser 
                805                 810                 815     


Val Thr Ser Ile Leu Lys Thr Leu Arg Gln Gln Thr Ser Ser Arg Pro 
            820                 825                 830         


Pro Ala Ser Val Gly Glu Leu Ser Ser Ser Gly Leu Gly Asp Pro Arg 
        835                 840                 845             


Leu Gln Lys Gly His Pro Thr Gly Ser Arg Leu Ala Asp Pro Arg Leu 
    850                 855                 860                 


Ser Arg Asp Pro Arg Leu Thr Arg His Val Glu Ala Ser Gly Gly Ser 
865                 870                 875                 880 


Gly Pro Gly Asp Ser Gly Pro Ser Asp Pro Arg Leu Ala Arg Ala Leu 
                885                 890                 895     


Pro Thr Ser Lys Pro Glu Gly Ser Leu His Ser Ser Pro Val Gly Pro 
            900                 905                 910         


Ser Ser Ser Lys Gly Ser Gly Pro Pro Pro Thr Glu Glu Glu Glu Gly 
        915                 920                 925             


Glu Arg Ala Leu Arg Glu Lys Ala Val Asn Ile Pro Leu Asp Pro Leu 
    930                 935                 940                 


Pro Gly His Pro Leu Arg Asp Pro Arg Ser Gln Leu Gln Gln Phe Ser 
945                 950                 955                 960 


His Ile Lys Lys Asp Val Thr Leu Ser Lys Pro Ser Phe Ala Arg Thr 
                965                 970                 975     


Val Leu Trp Asn Pro Glu Asp Leu Ile Pro Leu Pro Ile Pro Lys Gln 
            980                 985                 990         


Asp Ala Val Pro Pro Val Pro Ala  Ala Leu Gln Ser Met  Pro Thr Leu 
        995                 1000                 1005             


Asp Pro  Arg Leu His Arg Ala  Ala Thr Ala Gly Pro  Pro Asn Ala 
    1010                 1015                 1020             


Arg Gln  Arg Pro Gly Ala Ser  Thr Asp Ser Ser Thr  Gln Gly Ala 
    1025                 1030                 1035             


Asn Leu  Pro Asp Phe Glu Leu  Leu Ser Arg Ile Leu  Lys Thr Val 
    1040                 1045                 1050             


Asn Ala  Thr Gly Ser Ser Ala  Ala Pro Gly Ser Ser  Asp Lys Pro 
    1055                 1060                 1065             


Ser Asp  Pro Arg Val Arg Lys  Ala Pro Thr Asp Pro  Arg Leu Gln 
    1070                 1075                 1080             


Lys Pro  Thr Asp Ser Thr Ala  Ser Ser Arg Ala Ala  Lys Pro Gly 
    1085                 1090                 1095             


Pro Ala  Glu Ala Pro Ser Pro  Thr Ala Ser Pro Ser  Gly Asp Ala 
    1100                 1105                 1110             


Ser Pro  Pro Ala Thr Ala Pro  Tyr Asp Pro Arg Val  Leu Ala Ala 
    1115                 1120                 1125             


Gly Gly  Leu Gly Gln Gly Gly  Gly Gly Gly Gln Ser  Ser Val Leu 
    1130                 1135                 1140             


Ser Gly  Ile Ser Leu Tyr Asp  Pro Arg Thr Pro Asn  Ala Gly Gly 
    1145                 1150                 1155             


Lys Ala  Thr Glu Pro Ala Ala  Asp Thr Gly Ala Gln  Pro Lys Gly 
    1160                 1165                 1170             


Ala Glu  Gly Asn Gly Lys Ser  Ser Ala Ser Lys Ala  Lys Glu Pro 
    1175                 1180                 1185             


Pro Phe  Val Arg Lys Ser Ala  Leu Glu Gln Pro Glu  Thr Gly Lys 
    1190                 1195                 1200             


Ala Gly  Ala Asp Gly Gly Thr  Pro Thr Asp Arg Tyr  Asn Ser Tyr 
    1205                 1210                 1215             


Asn Arg  Pro Arg Pro Lys Ala  Ala Ala Ala Pro Ala  Ala Thr Thr 
    1220                 1225                 1230             


Ala Thr  Pro Pro Pro Glu Gly  Ala Pro Pro Gln Pro  Gly Val His 
    1235                 1240                 1245             


Asn Leu  Pro Val Pro Thr Leu  Phe Gly Thr Val Lys  Gln Thr Pro 
    1250                 1255                 1260             


Lys Thr  Gly Ser Gly Ser Pro  Phe Ala Gly Asn Ser  Pro Ala Arg 
    1265                 1270                 1275             


Glu Gly  Glu Gln Asp Ala Ala  Ser Leu Lys Asp Val  Phe Lys Gly 
    1280                 1285                 1290             


Phe Asp  Pro Thr Ala Ser Pro  Phe Cys Gln 
    1295                 1300             


<210>  3153
<211>  470
<212>  PRT
<213>  homo sapiens

<400>  3153

Met Ala Ala Thr Leu Leu Met Ala Gly Ser Gln Ala Pro Val Thr Phe 
1               5                   10                  15      


Glu Asp Met Ala Met Tyr Leu Thr Arg Glu Glu Trp Arg Pro Leu Asp 
            20                  25                  30          


Ala Ala Gln Arg Asp Leu Tyr Arg Asp Val Met Gln Glu Asn Tyr Gly 
        35                  40                  45              


Asn Val Val Ser Leu Asp Phe Glu Ile Arg Ser Glu Asn Glu Val Asn 
    50                  55                  60                  


Pro Lys Gln Glu Ile Ser Glu Asp Val Gln Phe Gly Thr Thr Ser Glu 
65                  70                  75                  80  


Arg Pro Ala Glu Asn Ala Glu Glu Asn Pro Glu Ser Glu Glu Gly Phe 
                85                  90                  95      


Glu Ser Gly Asp Arg Ser Glu Arg Gln Trp Gly Asp Leu Thr Ala Glu 
            100                 105                 110         


Glu Trp Val Ser Tyr Pro Leu Gln Pro Val Thr Asp Leu Leu Val His 
        115                 120                 125             


Lys Glu Val His Thr Gly Ile Arg Tyr His Ile Cys Ser His Cys Gly 
    130                 135                 140                 


Lys Ala Phe Ser Gln Ile Ser Asp Leu Asn Arg His Gln Lys Thr His 
145                 150                 155                 160 


Thr Gly Asp Arg Pro Tyr Lys Cys Tyr Glu Cys Gly Lys Gly Phe Ser 
                165                 170                 175     


Arg Ser Ser His Leu Ile Gln His Gln Arg Thr His Thr Gly Glu Arg 
            180                 185                 190         


Pro Tyr Asp Cys Asn Glu Cys Gly Lys Ser Phe Gly Arg Ser Ser His 
        195                 200                 205             


Leu Ile Gln His Gln Thr Ile His Thr Gly Glu Lys Pro His Lys Cys 
    210                 215                 220                 


Asn Glu Cys Gly Lys Ser Phe Cys Arg Leu Ser His Leu Ile Gln His 
225                 230                 235                 240 


Gln Arg Thr His Ser Gly Glu Lys Pro Tyr Glu Cys Glu Glu Cys Gly 
                245                 250                 255     


Lys Ser Phe Ser Arg Ser Ser His Leu Ala Gln His Gln Arg Thr His 
            260                 265                 270         


Thr Gly Glu Lys Pro Tyr Glu Cys Asn Glu Cys Gly Arg Gly Phe Ser 
        275                 280                 285             


Glu Arg Ser Asp Leu Ile Lys His Tyr Arg Val His Thr Gly Glu Arg 
    290                 295                 300                 


Pro Tyr Lys Cys Asp Glu Cys Gly Lys Asn Phe Ser Gln Asn Ser Asp 
305                 310                 315                 320 


Leu Val Arg His Arg Arg Ala His Thr Gly Glu Lys Pro Tyr His Cys 
                325                 330                 335     


Asn Glu Cys Gly Glu Asn Phe Ser Arg Ile Ser His Leu Val Gln His 
            340                 345                 350         


Gln Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Ala Cys Gly 
        355                 360                 365             


Lys Ser Phe Ser Arg Ser Ser His Leu Ile Thr His Gln Lys Ile His 
    370                 375                 380                 


Thr Gly Glu Lys Pro Tyr Glu Cys Asn Glu Cys Trp Arg Ser Phe Gly 
385                 390                 395                 400 


Glu Arg Ser Asp Leu Ile Lys His Gln Arg Thr His Thr Gly Glu Lys 
                405                 410                 415     


Pro Tyr Glu Cys Val Gln Cys Gly Lys Gly Phe Thr Gln Ser Ser Asn 
            420                 425                 430         


Leu Ile Thr His Gln Arg Val His Thr Gly Glu Lys Pro Tyr Glu Cys 
        435                 440                 445             


Thr Glu Cys Glu Lys Ser Phe Ser Arg Ser Ser Ala Leu Ile Lys His 
    450                 455                 460                 


Lys Arg Val His Thr Asp 
465                 470 


<210>  3154
<211>  646
<212>  PRT
<213>  homo sapiens

<400>  3154

Met Ser Thr Ala Pro Ser Leu Ser Ala Leu Arg Ser Ser Lys His Ser 
1               5                   10                  15      


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Asp Pro Ala Trp 
            20                  25                  30          


Thr Ser Ala Leu Ser Gly Asn Ser Ser Gly Pro Gly Pro Gly Ser Ser 
        35                  40                  45              


Pro Ala Gly Ser Thr Lys Pro Phe Val His Ala Val Pro Pro Ser Asp 
    50                  55                  60                  


Pro Leu Arg Gln Ala Asn Arg Leu Pro Ile Lys Val Leu Lys Met Leu 
65                  70                  75                  80  


Thr Ala Arg Thr Gly His Ile Leu His Pro Glu Tyr Leu Gln Pro Leu 
                85                  90                  95      


Pro Ser Thr Pro Val Ser Pro Ile Glu Leu Asp Ala Lys Lys Ser Pro 
            100                 105                 110         


Leu Ala Leu Leu Ala Gln Thr Cys Ser Gln Ile Gly Lys Pro Asp Pro 
        115                 120                 125             


Ser Pro Ser Ser Lys Leu Ser Ser Val Ala Ser Asn Gly Gly Gly Ala 
    130                 135                 140                 


Gly Gly Ala Gly Gly Gly Ala Ala Gly Asp Lys Asp Thr Lys Ser Gly 
145                 150                 155                 160 


Pro Leu Lys Leu Ser Asp Ile Gly Val Glu Asp Lys Ser Ser Phe Lys 
                165                 170                 175     


Pro Tyr Ser Lys Pro Gly Ser Asp Lys Lys Glu Pro Gly Gly Gly Gly 
            180                 185                 190         


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Val Ser Ser Glu 
        195                 200                 205             


Lys Ser Gly Phe Arg Val Pro Ser Ala Thr Cys Gln Pro Phe Thr Pro 
    210                 215                 220                 


Arg Thr Gly Ser Pro Ser Ser Ser Ala Ser Ala Cys Ser Pro Gly Gly 
225                 230                 235                 240 


Met Leu Ser Ser Ala Gly Gly Ala Pro Glu Gly Lys Asp Asp Lys Lys 
                245                 250                 255     


Asp Thr Asp Val Gly Gly Gly Gly Lys Gly Thr Gly Gly Ala Ser Ala 
            260                 265                 270         


Glu Gly Gly Pro Thr Gly Leu Ala His Gly Arg Ile Ser Cys Gly Gly 
        275                 280                 285             


Gly Ile Asn Val Asp Val Asn Gln His Pro Asp Gly Gly Pro Gly Gly 
    290                 295                 300                 


Lys Ala Leu Gly Ser Asp Cys Gly Gly Ser Ser Gly Ser Ser Ser Gly 
305                 310                 315                 320 


Ser Gly Pro Ser Ala Pro Thr Ser Ser Ser Val Leu Gly Ser Gly Leu 
                325                 330                 335     


Val Ala Pro Val Ser Pro Tyr Lys Pro Gly Gln Thr Val Phe Pro Leu 
            340                 345                 350         


Pro Pro Ala Gly Met Thr Tyr Pro Gly Ser Leu Ala Gly Ala Tyr Ala 
        355                 360                 365             


Gly Tyr Pro Pro Gln Phe Leu Pro His Gly Val Ala Leu Asp Pro Thr 
    370                 375                 380                 


Lys Pro Gly Ser Leu Val Gly Ala Gln Leu Ala Ala Ala Ala Ala Gly 
385                 390                 395                 400 


Ser Leu Gly Cys Ser Lys Pro Ala Gly Ser Ser Pro Leu Ala Gly Ala 
                405                 410                 415     


Ser Pro Pro Ser Val Met Thr Ala Ser Leu Cys Arg Asp Pro Tyr Cys 
            420                 425                 430         


Leu Ser Tyr His Cys Ala Ser His Leu Ala Gly Ala Ala Ala Ala Ser 
        435                 440                 445             


Ala Ser Cys Ala His Asp Pro Ala Ala Ala Ala Ala Ala Leu Lys Ser 
    450                 455                 460                 


Gly Tyr Pro Leu Val Tyr Pro Thr His Pro Leu His Gly Val His Ser 
465                 470                 475                 480 


Ser Leu Thr Ala Ala Ala Ala Ala Gly Ala Thr Pro Pro Ser Leu Ala 
                485                 490                 495     


Gly His Pro Leu Tyr Pro Tyr Gly Phe Met Leu Pro Asn Asp Pro Leu 
            500                 505                 510         


Pro His Ile Cys Asn Trp Val Ser Ala Asn Gly Pro Cys Asp Lys Arg 
        515                 520                 525             


Phe Ala Thr Ser Glu Glu Leu Leu Ser His Leu Arg Thr His Thr Ala 
    530                 535                 540                 


Phe Pro Gly Thr Asp Lys Leu Leu Ser Gly Tyr Pro Ser Ser Ser Ser 
545                 550                 555                 560 


Leu Ala Ser Ala Ala Ala Ala Ala Met Ala Cys His Met His Ile Pro 
                565                 570                 575     


Thr Ser Gly Ala Pro Gly Ser Pro Gly Thr Leu Ala Leu Arg Ser Pro 
            580                 585                 590         


His His Ala Leu Gly Leu Ser Ser Arg Tyr His Pro Tyr Ser Lys Ser 
        595                 600                 605             


Pro Leu Pro Thr Pro Gly Ala Pro Val Pro Val Pro Ala Ala Thr Gly 
    610                 615                 620                 


Pro Tyr Tyr Ser Pro Tyr Ala Leu Tyr Gly Gln Arg Leu Thr Thr Ala 
625                 630                 635                 640 


Ser Ala Leu Gly Tyr Gln 
                645     


<210>  3155
<211>  404
<212>  PRT
<213>  homo sapiens

<400>  3155

Met Ile Trp Lys Arg Ser Ala Val Leu Arg Phe Tyr Ser Val Cys Gly 
1               5                   10                  15      


Leu Leu Leu Gln Ala Ala Ala Ser Lys Asn Lys Val Lys Gly Ser Gln 
            20                  25                  30          


Gly Gln Phe Pro Leu Thr Gln Asn Val Thr Val Val Glu Gly Gly Thr 
        35                  40                  45              


Ala Ile Leu Thr Cys Arg Val Asp Gln Asn Asp Asn Thr Ser Leu Gln 
    50                  55                  60                  


Trp Ser Asn Pro Ala Gln Gln Thr Leu Tyr Phe Asp Asp Lys Lys Ala 
65                  70                  75                  80  


Leu Arg Asp Asn Arg Ile Glu Leu Val Arg Ala Ser Trp His Glu Leu 
                85                  90                  95      


Ser Ile Ser Val Ser Asp Val Ser Leu Ser Asp Glu Gly Gln Tyr Thr 
            100                 105                 110         


Cys Ser Leu Phe Thr Met Pro Val Lys Thr Ser Lys Ala Tyr Leu Thr 
        115                 120                 125             


Val Leu Gly Val Pro Glu Lys Pro Gln Ile Ser Gly Phe Ser Ser Pro 
    130                 135                 140                 


Val Met Glu Gly Asp Leu Met Gln Leu Thr Cys Lys Thr Ser Gly Ser 
145                 150                 155                 160 


Lys Pro Ala Ala Asp Ile Arg Trp Phe Lys Asn Asp Lys Glu Ile Lys 
                165                 170                 175     


Asp Val Lys Tyr Leu Lys Glu Glu Asp Ala Asn Arg Lys Thr Phe Thr 
            180                 185                 190         


Val Ser Ser Thr Leu Asp Phe Arg Val Asp Arg Ser Asp Asp Gly Val 
        195                 200                 205             


Ala Val Ile Cys Arg Val Asp His Glu Ser Leu Asn Ala Thr Pro Gln 
    210                 215                 220                 


Val Ala Met Gln Val Leu Glu Ile His Tyr Thr Pro Ser Val Lys Ile 
225                 230                 235                 240 


Ile Pro Ser Thr Pro Phe Pro Gln Glu Gly Gln Pro Leu Ile Leu Thr 
                245                 250                 255     


Cys Glu Ser Lys Gly Lys Pro Leu Pro Glu Pro Val Leu Trp Thr Lys 
            260                 265                 270         


Asp Gly Gly Glu Leu Pro Asp Pro Asp Arg Met Val Val Ser Gly Arg 
        275                 280                 285             


Glu Leu Asn Ile Leu Phe Leu Asn Lys Thr Asp Asn Gly Thr Tyr Arg 
    290                 295                 300                 


Cys Glu Ala Thr Asn Thr Ile Gly Gln Ser Ser Ala Glu Tyr Val Leu 
305                 310                 315                 320 


Ile Val His Asp Pro Asn Ala Leu Ala Gly Gln Asn Gly Pro Asp His 
                325                 330                 335     


Ala Leu Ile Gly Gly Ile Val Ala Val Val Val Phe Val Thr Leu Cys 
            340                 345                 350         


Ser Ile Phe Leu Leu Gly Arg Tyr Leu Ala Arg His Lys Gly Thr Tyr 
        355                 360                 365             


Leu Thr Asn Glu Ala Lys Gly Ala Glu Asp Ala Pro Asp Ala Asp Thr 
    370                 375                 380                 


Ala Ile Ile Asn Ala Glu Gly Ser Gln Val Asn Ala Glu Glu Lys Lys 
385                 390                 395                 400 


Glu Tyr Phe Ile 
                


<210>  3156
<211>  562
<212>  PRT
<213>  homo sapiens

<400>  3156

Met Cys Val Cys Pro Gly Pro Arg Arg Ile Gly Ile Pro Val Arg Ser 
1               5                   10                  15      


Ser Ser Leu Pro Leu Phe Ser Asp Ala Met Pro Ala Pro Thr Gln Leu 
            20                  25                  30          


Phe Phe Pro Leu Ile Arg Asn Cys Glu Leu Ser Arg Ile Tyr Gly Thr 
        35                  40                  45              


Ala Cys Tyr Cys His His Lys His Leu Cys Cys Ser Ser Ser Tyr Ile 
    50                  55                  60                  


Pro Gln Ser Arg Leu Arg Tyr Thr Pro His Pro Ala Tyr Ala Thr Phe 
65                  70                  75                  80  


Cys Arg Pro Lys Glu Asn Trp Trp Gln Tyr Thr Gln Gly Arg Arg Tyr 
                85                  90                  95      


Ala Ser Thr Pro Gln Lys Phe Tyr Leu Thr Pro Pro Gln Val Asn Ser 
            100                 105                 110         


Ile Leu Lys Ala Asn Glu Tyr Ser Phe Lys Val Pro Glu Phe Asp Gly 
        115                 120                 125             


Lys Asn Val Ser Ser Ile Leu Gly Phe Asp Ser Asn Gln Leu Pro Ala 
    130                 135                 140                 


Asn Ala Pro Ile Glu Asp Arg Arg Ser Ala Ala Thr Cys Leu Gln Thr 
145                 150                 155                 160 


Arg Gly Met Leu Leu Gly Val Phe Asp Gly His Ala Gly Cys Ala Cys 
                165                 170                 175     


Ser Gln Ala Val Ser Glu Arg Leu Phe Tyr Tyr Ile Ala Val Ser Leu 
            180                 185                 190         


Leu Pro His Glu Thr Leu Leu Glu Ile Glu Asn Ala Val Glu Ser Gly 
        195                 200                 205             


Arg Ala Leu Leu Pro Ile Leu Gln Trp His Lys His Pro Asn Asp Tyr 
    210                 215                 220                 


Phe Ser Lys Glu Ala Ser Lys Leu Tyr Phe Asn Ser Leu Arg Thr Tyr 
225                 230                 235                 240 


Trp Gln Glu Leu Ile Asp Leu Asn Thr Gly Glu Ser Thr Asp Ile Asp 
                245                 250                 255     


Val Lys Glu Ala Leu Ile Asn Ala Phe Lys Arg Leu Asp Asn Asp Ile 
            260                 265                 270         


Ser Leu Glu Ala Gln Val Gly Asp Pro Asn Ser Phe Leu Asn Tyr Leu 
        275                 280                 285             


Val Leu Arg Val Ala Phe Ser Gly Ala Thr Ala Cys Val Ala His Val 
    290                 295                 300                 


Asp Gly Val Asp Leu His Val Ala Asn Thr Gly Asp Ser Arg Ala Met 
305                 310                 315                 320 


Leu Gly Val Gln Glu Glu Asp Gly Ser Trp Ser Ala Val Thr Leu Ser 
                325                 330                 335     


Asn Asp His Asn Ala Gln Asn Glu Arg Glu Leu Glu Arg Leu Lys Leu 
            340                 345                 350         


Glu His Pro Lys Ser Glu Ala Lys Ser Val Val Lys Gln Asp Arg Leu 
        355                 360                 365             


Leu Gly Leu Leu Met Pro Phe Arg Ala Phe Gly Asp Val Lys Phe Lys 
    370                 375                 380                 


Trp Ser Ile Asp Leu Gln Lys Arg Val Ile Glu Ser Gly Pro Asp Gln 
385                 390                 395                 400 


Leu Asn Asp Asn Glu Tyr Thr Lys Phe Ile Pro Pro Asn Tyr His Thr 
                405                 410                 415     


Pro Pro Tyr Leu Thr Ala Glu Pro Glu Val Thr Tyr His Arg Leu Arg 
            420                 425                 430         


Pro Gln Asp Lys Phe Leu Val Leu Ala Thr Asp Gly Leu Trp Glu Thr 
        435                 440                 445             


Met His Arg Gln Asp Val Val Arg Ile Val Gly Glu Tyr Leu Thr Gly 
    450                 455                 460                 


Met His His Gln Gln Pro Ile Ala Val Gly Gly Tyr Lys Val Thr Leu 
465                 470                 475                 480 


Gly Gln Met His Gly Leu Leu Thr Glu Arg Arg Thr Lys Met Ser Ser 
                485                 490                 495     


Val Phe Glu Asp Gln Asn Ala Ala Thr His Leu Ile Arg His Ala Val 
            500                 505                 510         


Gly Asn Asn Glu Phe Gly Thr Val Asp His Glu Arg Leu Ser Lys Met 
        515                 520                 525             


Leu Ser Leu Pro Glu Glu Leu Ala Arg Met Tyr Arg Asp Asp Ile Thr 
    530                 535                 540                 


Ile Ile Val Val Gln Phe Asn Ser His Val Val Gly Ala Tyr Gln Asn 
545                 550                 555                 560 


Gln Glu 
        


<210>  3157
<211>  278
<212>  PRT
<213>  homo sapiens

<400>  3157

Met Pro Arg Leu Ser Leu Leu Leu Pro Leu Leu Leu Leu Leu Leu Leu 
1               5                   10                  15      


Pro Leu Leu Pro Pro Leu Ser Pro Ser Leu Gly Ile Arg Asp Val Gly 
            20                  25                  30          


Gly Arg Arg Pro Lys Cys Gly Pro Cys Arg Pro Glu Gly Cys Pro Ala 
        35                  40                  45              


Pro Ala Pro Cys Pro Ala Pro Gly Ile Ser Ala Leu Asp Glu Cys Gly 
    50                  55                  60                  


Cys Cys Ala Arg Cys Leu Gly Ala Glu Gly Ala Ser Cys Gly Gly Arg 
65                  70                  75                  80  


Ala Gly Gly Arg Cys Gly Pro Gly Leu Val Cys Ala Ser Gln Ala Ala 
                85                  90                  95      


Gly Ala Ala Pro Glu Gly Thr Gly Leu Cys Val Cys Ala Gln Arg Gly 
            100                 105                 110         


Thr Val Cys Gly Ser Asp Gly Arg Ser Tyr Pro Ser Val Cys Ala Leu 
        115                 120                 125             


Arg Leu Arg Ala Arg His Thr Pro Arg Ala His Pro Gly His Leu His 
    130                 135                 140                 


Lys Ala Arg Asp Gly Pro Cys Glu Phe Ala Pro Val Val Val Val Pro 
145                 150                 155                 160 


Pro Arg Ser Val His Asn Val Thr Gly Ala Gln Val Gly Leu Ser Cys 
                165                 170                 175     


Glu Val Arg Ala Val Pro Thr Pro Val Ile Thr Trp Arg Lys Val Thr 
            180                 185                 190         


Lys Ser Pro Glu Gly Thr Gln Ala Leu Glu Glu Leu Pro Gly Asp His 
        195                 200                 205             


Val Asn Ile Ala Val Gln Val Arg Gly Gly Pro Ser Asp His Glu Ala 
    210                 215                 220                 


Thr Ala Trp Ile Leu Ile Asn Pro Leu Arg Lys Glu Asp Glu Gly Val 
225                 230                 235                 240 


Tyr Gln Cys His Ala Ala Asn Met Val Gly Glu Ala Glu Ser His Ser 
                245                 250                 255     


Thr Val Thr Val Leu Asp Leu Ser Lys Tyr Arg Ser Phe His Phe Pro 
            260                 265                 270         


Ala Pro Asp Asp Arg Met 
        275             


<210>  3158
<211>  678
<212>  PRT
<213>  homo sapiens

<400>  3158

Met Ala Ala Asn Val Gly Ser Met Phe Gln Tyr Trp Lys Arg Phe Asp 
1               5                   10                  15      


Leu Gln Gln Leu Gln Arg Glu Leu Asp Ala Thr Ala Thr Val Leu Ala 
            20                  25                  30          


Asn Arg Gln Asp Glu Ser Glu Gln Ser Arg Lys Arg Leu Ile Glu Gln 
        35                  40                  45              


Ser Arg Glu Phe Lys Lys Asn Thr Pro Glu Asp Leu Arg Lys Gln Val 
    50                  55                  60                  


Ala Pro Leu Leu Lys Ser Phe Gln Gly Glu Ile Asp Ala Leu Ser Lys 
65                  70                  75                  80  


Arg Ser Lys Glu Ala Glu Ala Ala Phe Leu Asn Val Tyr Lys Arg Leu 
                85                  90                  95      


Ile Asp Val Pro Asp Pro Val Pro Ala Leu Asp Leu Gly Gln Gln Leu 
            100                 105                 110         


Gln Leu Lys Val Gln Arg Leu His Asp Ile Glu Thr Glu Asn Gln Lys 
        115                 120                 125             


Leu Arg Glu Thr Leu Glu Glu Tyr Asn Lys Glu Phe Ala Glu Val Lys 
    130                 135                 140                 


Asn Gln Glu Val Thr Ile Lys Ala Leu Lys Glu Lys Ile Arg Glu Tyr 
145                 150                 155                 160 


Glu Gln Thr Leu Lys Asn Gln Ala Glu Thr Ile Ala Leu Glu Lys Glu 
                165                 170                 175     


Gln Lys Leu Gln Asn Asp Phe Ala Glu Lys Glu Arg Lys Leu Gln Glu 
            180                 185                 190         


Thr Gln Met Ser Thr Thr Ser Lys Leu Glu Glu Ala Glu His Lys Val 
        195                 200                 205             


Gln Ser Leu Gln Thr Ala Leu Glu Lys Thr Arg Thr Glu Leu Phe Asp 
    210                 215                 220                 


Leu Lys Thr Lys Tyr Asp Glu Glu Thr Thr Ala Lys Ala Asp Glu Ile 
225                 230                 235                 240 


Glu Met Ile Met Thr Asp Leu Glu Arg Ala Asn Gln Arg Ala Glu Val 
                245                 250                 255     


Ala Gln Arg Glu Ala Glu Thr Leu Arg Glu Gln Leu Ser Ser Ala Asn 
            260                 265                 270         


His Ser Leu Gln Leu Ala Ser Gln Ile Gln Lys Ala Pro Asp Val Glu 
        275                 280                 285             


Gln Ala Ile Glu Val Leu Thr Arg Ser Ser Leu Glu Val Glu Leu Ala 
    290                 295                 300                 


Ala Lys Glu Arg Glu Ile Ala Gln Leu Val Glu Asp Val Gln Arg Leu 
305                 310                 315                 320 


Gln Ala Ser Leu Thr Lys Leu Arg Glu Asn Ser Ala Ser Gln Ile Ser 
                325                 330                 335     


Gln Leu Glu Gln Gln Leu Ser Ala Lys Asn Ser Thr Leu Lys Gln Leu 
            340                 345                 350         


Glu Glu Lys Leu Lys Gly Gln Ala Asp Tyr Glu Glu Val Lys Lys Glu 
        355                 360                 365             


Leu Asn Ile Leu Lys Ser Met Glu Phe Ala Pro Ser Glu Gly Ala Gly 
    370                 375                 380                 


Thr Gln Asp Ala Ala Lys Pro Leu Glu Val Leu Leu Leu Glu Lys Asn 
385                 390                 395                 400 


Arg Ser Leu Gln Ser Glu Asn Ala Ala Leu Arg Ile Ser Asn Ser Asp 
                405                 410                 415     


Leu Ser Gly Arg Cys Ala Glu Leu Gln Val Arg Ile Thr Glu Ala Val 
            420                 425                 430         


Ala Thr Ala Thr Glu Gln Arg Glu Leu Ile Ala Arg Leu Glu Gln Asp 
        435                 440                 445             


Leu Ser Ile Ile Gln Ser Ile Gln Arg Pro Asp Ala Glu Gly Ala Ala 
    450                 455                 460                 


Glu His Arg Leu Glu Lys Ile Pro Glu Pro Ile Lys Glu Ala Thr Ala 
465                 470                 475                 480 


Leu Phe Tyr Gly Pro Ala Ala Pro Ala Ser Gly Ala Leu Pro Glu Gly 
                485                 490                 495     


Gln Val Asp Ser Leu Leu Ser Ile Ile Ser Ser Gln Arg Glu Arg Phe 
            500                 505                 510         


Arg Ala Arg Asn Gln Glu Leu Glu Ala Glu Asn Arg Leu Ala Gln His 
        515                 520                 525             


Thr Leu Gln Ala Leu Gln Ser Glu Leu Asp Ser Leu Arg Ala Asp Asn 
    530                 535                 540                 


Ile Lys Leu Phe Glu Lys Ile Lys Phe Leu Gln Ser Tyr Pro Gly Arg 
545                 550                 555                 560 


Gly Ser Gly Ser Asp Asp Thr Glu Leu Arg Tyr Ser Ser Gln Tyr Glu 
                565                 570                 575     


Glu Arg Leu Asp Pro Phe Ser Ser Phe Ser Lys Arg Glu Arg Gln Arg 
            580                 585                 590         


Lys Tyr Leu Ser Leu Ser Pro Trp Asp Lys Ala Thr Leu Ser Met Gly 
        595                 600                 605             


Arg Leu Val Leu Ser Asn Lys Met Ala Arg Thr Ile Gly Phe Phe Tyr 
    610                 615                 620                 


Thr Leu Phe Leu His Cys Leu Val Phe Leu Val Leu Tyr Lys Leu Ala 
625                 630                 635                 640 


Trp Ser Glu Ser Met Glu Arg Asp Cys Ala Thr Phe Cys Ala Lys Lys 
                645                 650                 655     


Phe Ala Asp His Leu His Lys Phe His Glu Asn Asp Asn Gly Ala Ala 
            660                 665                 670         


Ala Gly Asp Leu Trp Gln 
        675             


<210>  3159
<211>  2856
<212>  PRT
<213>  homo sapiens

<400>  3159

Met Glu Glu Lys Gln Gln Ile Ile Leu Ala Asn Gln Asp Gly Gly Thr 
1               5                   10                  15      


Val Ala Gly Ala Ala Pro Thr Phe Phe Val Ile Leu Lys Gln Pro Gly 
            20                  25                  30          


Asn Gly Lys Thr Asp Gln Gly Ile Leu Val Thr Asn Gln Asp Ala Cys 
        35                  40                  45              


Ala Leu Ala Ser Ser Val Ser Ser Pro Val Lys Ser Lys Gly Lys Ile 
    50                  55                  60                  


Cys Leu Pro Ala Asp Cys Thr Val Gly Gly Ile Thr Val Thr Leu Asp 
65                  70                  75                  80  


Asn Asn Ser Met Trp Asn Glu Phe Tyr His Arg Ser Thr Glu Met Ile 
                85                  90                  95      


Leu Thr Lys Gln Gly Arg Arg Met Phe Pro Tyr Cys Arg Tyr Trp Ile 
            100                 105                 110         


Thr Gly Leu Asp Ser Asn Leu Lys Tyr Ile Leu Val Met Asp Ile Ser 
        115                 120                 125             


Pro Val Asp Asn His Arg Tyr Lys Trp Asn Gly Arg Trp Trp Glu Pro 
    130                 135                 140                 


Ser Gly Lys Ala Glu Pro His Val Leu Gly Arg Val Phe Ile His Pro 
145                 150                 155                 160 


Glu Ser Pro Ser Thr Gly His Tyr Trp Met His Gln Pro Val Ser Phe 
                165                 170                 175     


Tyr Lys Leu Lys Leu Thr Asn Asn Thr Leu Asp Gln Glu Gly His Ile 
            180                 185                 190         


Ile Leu His Ser Met His Arg Tyr Leu Pro Arg Leu His Leu Val Pro 
        195                 200                 205             


Ala Glu Lys Ala Val Glu Val Ile Gln Leu Asn Gly Pro Gly Val His 
    210                 215                 220                 


Thr Phe Thr Phe Pro Gln Thr Glu Phe Phe Ala Val Thr Ala Tyr Gln 
225                 230                 235                 240 


Asn Ile Gln Ile Thr Gln Leu Lys Ile Asp Tyr Asn Pro Phe Ala Lys 
                245                 250                 255     


Gly Phe Arg Asp Asp Gly Leu Asn Asn Lys Pro Gln Arg Asp Gly Lys 
            260                 265                 270         


Gln Lys Asn Ser Ser Asp Gln Glu Gly Asn Asn Ile Ser Ser Ser Ser 
        275                 280                 285             


Gly His Arg Val Arg Leu Thr Glu Gly Gln Gly Ser Glu Ile Gln Pro 
    290                 295                 300                 


Gly Asp Leu Asp Pro Leu Ser Arg Gly His Glu Thr Ser Gly Lys Gly 
305                 310                 315                 320 


Leu Glu Lys Thr Ser Leu Asn Ile Lys Arg Asp Phe Leu Gly Phe Met 
                325                 330                 335     


Asp Thr Asp Ser Ala Leu Ser Glu Val Pro Gln Leu Lys Gln Glu Ile 
            340                 345                 350         


Ser Glu Cys Leu Ile Ala Ser Ser Phe Glu Asp Asp Ser Arg Val Ala 
        355                 360                 365             


Ser Pro Leu Asp Gln Asn Gly Ser Phe Asn Val Val Ile Lys Glu Glu 
    370                 375                 380                 


Pro Leu Asp Asp Tyr Asp Tyr Glu Leu Gly Glu Cys Pro Glu Gly Val 
385                 390                 395                 400 


Thr Val Lys Gln Glu Glu Thr Asp Glu Glu Thr Asp Val Tyr Ser Asn 
                405                 410                 415     


Ser Asp Asp Asp Pro Ile Leu Glu Lys Gln Leu Lys Arg His Asn Lys 
            420                 425                 430         


Val Asp Asn Pro Glu Ala Asp His Leu Ser Ser Lys Trp Leu Pro Ser 
        435                 440                 445             


Ser Pro Ser Gly Val Ala Lys Ala Lys Met Phe Lys Leu Asp Thr Gly 
    450                 455                 460                 


Lys Met Pro Val Val Tyr Leu Glu Pro Cys Ala Val Thr Arg Ser Thr 
465                 470                 475                 480 


Val Lys Ile Ser Glu Leu Pro Asp Asn Met Leu Ser Thr Ser Arg Lys 
                485                 490                 495     


Asp Lys Ser Ser Met Leu Ala Glu Leu Glu Tyr Leu Pro Thr Tyr Ile 
            500                 505                 510         


Glu Asn Ser Asn Glu Thr Ala Phe Cys Leu Gly Lys Glu Ser Glu Asn 
        515                 520                 525             


Gly Leu Arg Lys His Ser Pro Asp Leu Arg Val Val Gln Lys Tyr Pro 
    530                 535                 540                 


Leu Leu Lys Glu Pro Gln Trp Lys Tyr Pro Asp Ile Ser Asp Ser Ile 
545                 550                 555                 560 


Ser Thr Glu Arg Ile Leu Asp Asp Ser Lys Asp Ser Val Gly Asp Ser 
                565                 570                 575     


Leu Ser Gly Lys Glu Asp Leu Gly Arg Lys Arg Thr Thr Met Leu Lys 
            580                 585                 590         


Ile Ala Thr Ala Ala Lys Val Val Asn Ala Asn Gln Asn Ala Ser Pro 
        595                 600                 605             


Asn Val Pro Gly Lys Arg Gly Arg Pro Arg Lys Leu Lys Leu Cys Lys 
    610                 615                 620                 


Ala Gly Arg Pro Pro Lys Asn Thr Gly Lys Ser Leu Ile Ser Thr Lys 
625                 630                 635                 640 


Asn Thr Pro Val Ser Pro Gly Ser Thr Phe Pro Asp Val Lys Pro Asp 
                645                 650                 655     


Leu Glu Asp Val Asp Gly Val Leu Phe Val Ser Phe Glu Ser Lys Glu 
            660                 665                 670         


Ala Leu Asp Ile His Ala Val Asp Gly Thr Thr Glu Glu Ser Ser Ser 
        675                 680                 685             


Leu Gln Ala Ser Thr Thr Asn Asp Ser Gly Tyr Arg Ala Arg Ile Ser 
    690                 695                 700                 


Gln Leu Glu Lys Glu Leu Ile Glu Asp Leu Lys Thr Leu Arg His Lys 
705                 710                 715                 720 


Gln Val Ile His Pro Gly Leu Gln Glu Val Gly Leu Lys Leu Asn Ser 
                725                 730                 735     


Val Asp Pro Thr Met Ser Ile Asp Leu Lys Tyr Leu Gly Val Gln Leu 
            740                 745                 750         


Pro Leu Ala Pro Ala Thr Ser Phe Pro Phe Trp Asn Leu Thr Gly Thr 
        755                 760                 765             


Asn Pro Ala Ser Pro Asp Ala Gly Phe Pro Phe Val Ser Arg Thr Gly 
    770                 775                 780                 


Lys Thr Asn Asp Phe Thr Lys Ile Lys Gly Trp Arg Gly Lys Phe His 
785                 790                 795                 800 


Ser Ala Ser Ala Ser Arg Asn Glu Gly Gly Asn Ser Glu Ser Ser Leu 
                805                 810                 815     


Lys Asn Arg Ser Ala Phe Cys Ser Asp Lys Leu Asp Glu Tyr Leu Glu 
            820                 825                 830         


Asn Glu Gly Lys Leu Met Glu Thr Ser Met Gly Phe Ser Ser Asn Ala 
        835                 840                 845             


Pro Thr Ser Pro Val Val Tyr Gln Leu Pro Thr Lys Ser Thr Ser Tyr 
    850                 855                 860                 


Val Arg Thr Leu Asp Ser Val Leu Lys Lys Gln Ser Thr Ile Ser Pro 
865                 870                 875                 880 


Ser Thr Ser Tyr Ser Leu Lys Pro His Ser Val Pro Pro Val Ser Arg 
                885                 890                 895     


Lys Ala Lys Ser Gln Asn Arg Gln Ala Thr Phe Ser Gly Arg Thr Lys 
            900                 905                 910         


Ser Ser Tyr Lys Ser Ile Leu Pro Tyr Pro Val Ser Pro Lys Gln Lys 
        915                 920                 925             


Tyr Ser His Val Ile Leu Gly Asp Lys Val Thr Lys Asn Ser Ser Gly 
    930                 935                 940                 


Ile Ile Ser Glu Asn Gln Ala Asn Asn Phe Val Val Pro Thr Leu Asp 
945                 950                 955                 960 


Glu Asn Ile Phe Pro Lys Gln Ile Ser Leu Arg Gln Ala Gln Gln Gln 
                965                 970                 975     


Gln Gln Gln Gln Gln Gly Ser Arg Pro Pro Gly Leu Ser Lys Ser Gln 
            980                 985                 990         


Val Lys Leu Met Asp Leu Glu Asp  Cys Ala Leu Trp Glu  Gly Lys Pro 
        995                 1000                 1005             


Arg Thr  Tyr Ile Thr Glu Glu  Arg Ala Asp Val Ser  Leu Thr Thr 
    1010                 1015                 1020             


Leu Leu  Thr Ala Gln Ala Ser  Leu Lys Thr Lys Pro  Ile His Thr 
    1025                 1030                 1035             


Ile Ile  Arg Lys Arg Ala Pro  Pro Cys Asn Asn Asp  Phe Cys Arg 
    1040                 1045                 1050             


Leu Gly  Cys Val Cys Ser Ser  Leu Ala Leu Glu Lys  Arg Gln Pro 
    1055                 1060                 1065             


Ala His  Cys Arg Arg Pro Asp  Cys Met Phe Gly Cys  Thr Cys Leu 
    1070                 1075                 1080             


Lys Arg  Lys Val Val Leu Val  Lys Gly Gly Ser Lys  Thr Lys His 
    1085                 1090                 1095             


Phe Gln  Arg Lys Ala Ala His  Arg Asp Pro Val Phe  Tyr Asp Thr 
    1100                 1105                 1110             


Leu Gly  Glu Glu Ala Arg Glu  Glu Glu Glu Gly Ile  Arg Glu Glu 
    1115                 1120                 1125             


Glu Glu  Gln Leu Lys Glu Lys  Lys Lys Arg Lys Lys  Leu Glu Tyr 
    1130                 1135                 1140             


Thr Ile  Cys Glu Thr Glu Pro  Glu Gln Pro Val Arg  His Tyr Pro 
    1145                 1150                 1155             


Leu Trp  Val Lys Val Glu Gly  Glu Val Asp Pro Glu  Pro Val Tyr 
    1160                 1165                 1170             


Ile Pro  Thr Pro Ser Val Ile  Glu Pro Met Lys Pro  Leu Leu Leu 
    1175                 1180                 1185             


Pro Gln  Pro Glu Val Leu Ser  Pro Thr Val Lys Gly  Lys Leu Leu 
    1190                 1195                 1200             


Thr Gly  Ile Lys Ser Pro Arg  Ser Tyr Thr Pro Lys  Pro Asn Pro 
    1205                 1210                 1215             


Val Ile  Arg Glu Glu Asp Lys  Asp Pro Val Tyr Leu  Tyr Phe Glu 
    1220                 1225                 1230             


Ser Met  Met Thr Cys Ala Arg  Val Arg Val Tyr Glu  Arg Lys Lys 
    1235                 1240                 1245             


Glu Asp  Gln Arg Gln Pro Ser  Ser Ser Ser Ser Pro  Ser Pro Ser 
    1250                 1255                 1260             


Phe Gln  Gln Gln Thr Ser Cys  His Ser Ser Pro Glu  Asn His Asn 
    1265                 1270                 1275             


Asn Ala  Lys Glu Pro Asp Ser  Glu Gln Gln Pro Leu  Lys Gln Leu 
    1280                 1285                 1290             


Thr Cys  Asp Leu Glu Asp Asp  Ser Asp Lys Leu Gln  Glu Lys Ser 
    1295                 1300                 1305             


Trp Lys  Ser Ser Cys Asn Glu  Gly Glu Ser Ser Ser  Thr Ser Tyr 
    1310                 1315                 1320             


Met His  Gln Arg Ser Pro Gly  Gly Pro Thr Lys Leu  Ile Glu Ile 
    1325                 1330                 1335             


Ile Ser  Asp Cys Asn Trp Glu  Glu Asp Arg Asn Lys  Ile Leu Ser 
    1340                 1345                 1350             


Ile Leu  Ser Gln His Ile Asn  Ser Asn Met Pro Gln  Ser Leu Lys 
    1355                 1360                 1365             


Val Gly  Ser Phe Ile Ile Glu  Leu Ala Ser Gln Arg  Lys Ser Arg 
    1370                 1375                 1380             


Gly Glu  Lys Asn Pro Pro Val  Tyr Ser Ser Arg Val  Lys Ile Ser 
    1385                 1390                 1395             


Met Pro  Ser Cys Gln Asp Gln  Asp Asp Met Ala Glu  Lys Ser Gly 
    1400                 1405                 1410             


Ser Glu  Thr Pro Asp Gly Pro  Leu Ser Pro Gly Lys  Met Glu Asp 
    1415                 1420                 1425             


Ile Ser  Pro Val Gln Thr Asp  Ala Leu Asp Ser Val  Arg Glu Arg 
    1430                 1435                 1440             


Leu His  Gly Gly Lys Gly Leu  Pro Phe Tyr Ala Gly  Leu Ser Pro 
    1445                 1450                 1455             


Ala Gly  Lys Leu Val Ala Tyr  Lys Arg Lys Pro Ser  Ser Ser Thr 
    1460                 1465                 1470             


Ser Gly  Leu Ile Gln Val Ala  Ser Asn Ala Lys Val  Ala Ala Ser 
    1475                 1480                 1485             


Arg Lys  Pro Arg Thr Leu Leu  Pro Ser Thr Ser Asn  Ser Lys Met 
    1490                 1495                 1500             


Ala Ser  Ser Ser Gly Thr Ala  Thr Asn Arg Pro Gly  Lys Asn Leu 
    1505                 1510                 1515             


Lys Ala  Phe Val Pro Ala Lys  Arg Pro Ile Glu Asn  Ala Ala Gln 
    1520                 1525                 1530             


Ile Pro  Val Ala Thr Pro Gln  Val Ser Pro Asn Thr  Val Lys Arg 
    1535                 1540                 1545             


Ala Gly  Pro Arg Leu Leu Leu  Ile Pro Val Gln Gln  Gly Ser Pro 
    1550                 1555                 1560             


Thr Leu  Arg Pro Val Ser Asn  Thr Gln Leu Gln Gly  His Arg Met 
    1565                 1570                 1575             


Val Leu  Gln Pro Val Arg Ser  Pro Ser Gly Met Asn  Leu Phe Arg 
    1580                 1585                 1590             


His Pro  Asn Gly Gln Ile Val  Gln Leu Leu Pro Leu  His Gln Leu 
    1595                 1600                 1605             


Arg Gly  Ser Asn Thr Gln Pro  Asn Leu Gln Pro Val  Met Phe Arg 
    1610                 1615                 1620             


Asn Pro  Gly Ser Val Met Gly  Ile Arg Leu Pro Ala  Pro Ser Lys 
    1625                 1630                 1635             


Pro Ser  Glu Thr Pro Pro Ser  Ser Thr Ser Ser Ser  Ala Phe Ser 
    1640                 1645                 1650             


Val Met  Asn Pro Val Ile Gln  Ala Val Gly Ser Ser  Ser Ala Val 
    1655                 1660                 1665             


Asn Val  Ile Thr Gln Ala Pro  Ser Leu Leu Ser Ser  Gly Ala Ser 
    1670                 1675                 1680             


Phe Val  Ser Gln Ala Gly Thr  Leu Thr Leu Arg Ile  Ser Pro Pro 
    1685                 1690                 1695             


Glu Pro  Gln Ser Phe Ala Ser  Lys Thr Gly Ser Glu  Thr Lys Ile 
    1700                 1705                 1710             


Thr Tyr  Ser Ser Gly Gly Gln  Pro Val Gly Thr Ala  Ser Leu Ile 
    1715                 1720                 1725             


Pro Leu  Gln Ser Gly Ser Phe  Ala Leu Leu Gln Leu  Pro Gly Gln 
    1730                 1735                 1740             


Lys Pro  Val Pro Ser Ser Ile  Leu Gln His Val Ala  Ser Leu Gln 
    1745                 1750                 1755             


Met Lys  Arg Glu Ser Gln Asn  Pro Asp Gln Lys Asp  Glu Thr Asn 
    1760                 1765                 1770             


Ser Ile  Lys Arg Glu Gln Glu  Thr Lys Lys Val Leu  Gln Ser Glu 
    1775                 1780                 1785             


Gly Glu  Ala Val Asp Pro Glu  Ala Asn Val Ile Lys  Gln Asn Ser 
    1790                 1795                 1800             


Gly Ala  Ala Thr Ser Glu Glu  Thr Leu Asn Asp Ser  Leu Glu Asp 
    1805                 1810                 1815             


Arg Gly  Asp His Leu Asp Glu  Glu Cys Leu Pro Glu  Glu Gly Cys 
    1820                 1825                 1830             


Ala Thr  Val Lys Pro Ser Glu  His Ser Cys Ile Thr  Gly Ser His 
    1835                 1840                 1845             


Thr Asp  Gln Asp Tyr Lys Asp  Val Asn Glu Glu Tyr  Gly Ala Arg 
    1850                 1855                 1860             


Asn Arg  Lys Ser Ser Lys Glu  Lys Val Ala Val Leu  Glu Val Arg 
    1865                 1870                 1875             


Thr Ile  Ser Glu Lys Ala Ser  Asn Lys Thr Val Gln  Asn Leu Ser 
    1880                 1885                 1890             


Lys Val  Gln His Gln Lys Leu  Gly Asp Val Lys Val  Glu Gln Gln 
    1895                 1900                 1905             


Lys Gly  Phe Asp Asn Pro Glu  Glu Asn Ser Ser Glu  Phe Pro Val 
    1910                 1915                 1920             


Thr Phe  Lys Glu Glu Ser Lys  Phe Glu Leu Ser Gly  Ser Lys Val 
    1925                 1930                 1935             


Met Glu  Gln Gln Ser Asn Leu  Gln Pro Glu Ala Lys  Glu Lys Glu 
    1940                 1945                 1950             


Cys Gly  Asp Ser Leu Glu Lys  Asp Arg Glu Arg Trp  Arg Lys His 
    1955                 1960                 1965             


Leu Lys  Gly Pro Leu Thr Arg  Lys Cys Val Gly Ala  Ser Gln Glu 
    1970                 1975                 1980             


Cys Lys  Lys Glu Ala Asp Glu  Gln Leu Ile Lys Glu  Thr Lys Thr 
    1985                 1990                 1995             


Cys Gln  Glu Asn Ser Asp Val  Phe Gln Gln Glu Gln  Gly Ile Ser 
    2000                 2005                 2010             


Asp Leu  Leu Gly Lys Ser Gly  Ile Thr Glu Asp Ala  Arg Val Leu 
    2015                 2020                 2025             


Lys Thr  Glu Cys Asp Ser Trp  Ser Arg Ile Ser Asn  Pro Ser Ala 
    2030                 2035                 2040             


Phe Ser  Ile Val Pro Arg Arg  Ala Ala Lys Ser Ser  Arg Gly Asn 
    2045                 2050                 2055             


Gly His  Phe Gln Gly His Leu  Leu Leu Pro Gly Glu  Gln Ile Gln 
    2060                 2065                 2070             


Pro Lys  Gln Glu Lys Lys Gly  Gly Arg Ser Ser Ala  Asp Phe Thr 
    2075                 2080                 2085             


Val Leu  Asp Leu Glu Glu Asp  Asp Glu Asp Asp Asn  Glu Lys Thr 
    2090                 2095                 2100             


Asp Asp  Ser Ile Asp Glu Ile  Val Asp Val Val Ser  Asp Tyr Gln 
    2105                 2110                 2115             


Ser Glu  Glu Val Asp Asp Val  Glu Lys Asn Asn Cys  Val Glu Tyr 
    2120                 2125                 2130             


Ile Glu  Asp Asp Glu Glu His  Val Asp Ile Glu Thr  Val Glu Glu 
    2135                 2140                 2145             


Leu Ser  Glu Glu Ile Asn Val  Ala His Leu Lys Thr  Thr Ala Ala 
    2150                 2155                 2160             


His Thr  Gln Ser Phe Lys Gln  Pro Ser Cys Thr His  Ile Ser Ala 
    2165                 2170                 2175             


Asp Glu  Lys Ala Ala Glu Arg  Ser Arg Lys Ala Pro  Pro Ile Pro 
    2180                 2185                 2190             


Leu Lys  Leu Lys Pro Asp Tyr  Trp Ser Asp Lys Leu  Gln Lys Glu 
    2195                 2200                 2205             


Ala Glu  Ala Phe Ala Tyr Tyr  Arg Arg Thr His Thr  Ala Asn Glu 
    2210                 2215                 2220             


Arg Arg  Arg Arg Gly Glu Met  Arg Asp Leu Phe Glu  Lys Leu Lys 
    2225                 2230                 2235             


Ile Thr  Leu Gly Leu Leu His  Ser Ser Lys Val Ser  Lys Ser Leu 
    2240                 2245                 2250             


Ile Leu  Thr Arg Ala Phe Ser  Glu Ile Gln Gly Leu  Thr Asp Gln 
    2255                 2260                 2265             


Ala Asp  Lys Leu Ile Gly Gln  Lys Asn Leu Leu Thr  Arg Lys Arg 
    2270                 2275                 2280             


Asn Ile  Leu Ile Arg Lys Val  Ser Ser Leu Ser Gly  Lys Thr Glu 
    2285                 2290                 2295             


Glu Val  Val Leu Lys Lys Leu  Glu Tyr Ile Tyr Ala  Lys Gln Gln 
    2300                 2305                 2310             


Ala Leu  Glu Ala Gln Lys Arg  Lys Lys Lys Met Gly  Ser Asp Glu 
    2315                 2320                 2325             


Phe Asp  Ile Ser Pro Arg Ile  Ser Lys Gln Gln Glu  Gly Ser Ser 
    2330                 2335                 2340             


Ala Ser  Ser Val Asp Leu Gly  Gln Met Phe Ile Asn  Asn Arg Arg 
    2345                 2350                 2355             


Gly Lys  Pro Leu Ile Leu Ser  Arg Lys Lys Asp Gln  Ala Thr Glu 
    2360                 2365                 2370             


Asn Thr  Ser Pro Leu Asn Thr  Pro His Thr Ser Ala  Asn Leu Val 
    2375                 2380                 2385             


Met Thr  Pro Gln Gly Gln Leu  Leu Thr Leu Lys Gly  Pro Leu Phe 
    2390                 2395                 2400             


Ser Gly  Pro Val Val Ala Val  Ser Pro Asp Leu Leu  Glu Ser Asp 
    2405                 2410                 2415             


Leu Lys  Pro Gln Val Ala Gly  Ser Ala Val Ala Leu  Pro Glu Asn 
    2420                 2425                 2430             


Asp Asp  Leu Phe Met Met Pro  Arg Ile Val Asn Val  Thr Ser Leu 
    2435                 2440                 2445             


Ala Thr  Glu Gly Gly Leu Val  Asp Met Gly Gly Ser  Lys Tyr Pro 
    2450                 2455                 2460             


His Glu  Val Pro Asp Ser Lys  Pro Ser Asp His Leu  Lys Asp Thr 
    2465                 2470                 2475             


Val Arg  Asn Glu Asp Asn Ser  Leu Glu Asp Lys Gly  Arg Ile Ser 
    2480                 2485                 2490             


Ser Arg  Gly Asn Arg Asp Gly  Arg Val Thr Leu Gly  Pro Thr Gln 
    2495                 2500                 2505             


Val Phe  Leu Ala Asn Lys Asp  Ser Gly Tyr Pro Gln  Ile Val Asp 
    2510                 2515                 2520             


Val Ser  Asn Met Gln Lys Ala  Gln Glu Phe Leu Pro  Lys Lys Ile 
    2525                 2530                 2535             


Ser Gly  Asp Met Arg Gly Ile  Gln Tyr Lys Trp Lys  Glu Ser Glu 
    2540                 2545                 2550             


Ser Arg  Gly Glu Arg Val Lys  Ser Lys Asp Ser Ser  Phe His Lys 
    2555                 2560                 2565             


Leu Lys  Met Lys Asp Leu Lys  Asp Ser Ser Ile Glu  Met Glu Leu 
    2570                 2575                 2580             


Arg Lys  Val Thr Ser Ala Ile  Glu Glu Ala Ala Leu  Asp Ser Ser 
    2585                 2590                 2595             


Glu Leu  Leu Thr Asn Met Glu  Asp Glu Asp Asp Thr  Asp Glu Thr 
    2600                 2605                 2610             


Leu Thr  Ser Leu Leu Asn Glu  Ile Ala Phe Leu Asn  Gln Gln Leu 
    2615                 2620                 2625             


Asn Asp  Asp Ser Val Gly Leu  Ala Glu Leu Pro Ser  Ser Met Asp 
    2630                 2635                 2640             


Thr Glu  Phe Pro Gly Asp Ala  Arg Arg Ala Phe Ile  Ser Lys Val 
    2645                 2650                 2655             


Pro Pro  Gly Ser Arg Ala Thr  Phe Gln Val Glu His  Leu Gly Thr 
    2660                 2665                 2670             


Gly Leu  Lys Glu Leu Pro Asp  Val Gln Gly Glu Ser  Asp Ser Ile 
    2675                 2680                 2685             


Ser Pro  Leu Leu Leu His Leu  Glu Asp Asp Asp Phe  Ser Glu Asn 
    2690                 2695                 2700             


Glu Lys  Gln Leu Ala Glu Pro  Ala Ser Glu Pro Asp  Val Leu Lys 
    2705                 2710                 2715             


Ile Val  Ile Asp Ser Glu Ile  Lys Asp Ser Leu Leu  Ser Asn Lys 
    2720                 2725                 2730             


Lys Ala  Ile Asp Gly Gly Lys  Asn Thr Ser Gly Leu  Pro Ala Glu 
    2735                 2740                 2745             


Pro Glu  Ser Val Ser Ser Pro  Pro Thr Leu His Met  Lys Thr Gly 
    2750                 2755                 2760             


Leu Glu  Asn Ser Asn Ser Thr  Asp Thr Leu Trp Arg  Pro Met Pro 
    2765                 2770                 2775             


Lys Leu  Ala Pro Leu Gly Leu  Lys Val Ala Asn Pro  Ser Ser Asp 
    2780                 2785                 2790             


Ala Asp  Gly Gln Ser Leu Lys  Val Met Pro Cys Leu  Ala Pro Ile 
    2795                 2800                 2805             


Ala Ala  Lys Val Gly Ser Val  Gly His Lys Met Asn  Leu Thr Gly 
    2810                 2815                 2820             


Asn Asp  Gln Glu Gly Arg Glu  Ser Lys Val Met Pro  Thr Leu Ala 
    2825                 2830                 2835             


Pro Val  Val Ala Lys Leu Gly  Asn Ser Gly Ala Ser  Pro Ser Ser 
    2840                 2845                 2850             


Ala Gly  Lys 
    2855     


<210>  3160
<211>  154
<212>  PRT
<213>  homo sapiens

<400>  3160

Met Ala Ser Ala Ser Ala Arg Gly Asn Gln Asp Lys Asp Ala His Phe 
1               5                   10                  15      


Pro Pro Pro Ser Lys Gln Ser Leu Leu Phe Cys Pro Lys Ser Lys Leu 
            20                  25                  30          


His Ile His Arg Ala Glu Ile Ser Lys Ile Met Arg Glu Cys Gln Glu 
        35                  40                  45              


Glu Ser Phe Trp Lys Arg Ala Leu Pro Phe Ser Leu Val Ser Met Leu 
    50                  55                  60                  


Val Thr Gln Gly Leu Val Tyr Gln Gly Tyr Leu Ala Ala Asn Ser Arg 
65                  70                  75                  80  


Phe Gly Ser Leu Pro Lys Val Ala Leu Ala Gly Leu Leu Gly Phe Gly 
                85                  90                  95      


Leu Gly Lys Val Ser Tyr Ile Gly Val Cys Gln Ser Lys Phe His Phe 
            100                 105                 110         


Phe Glu Asp Gln Leu Arg Gly Ala Gly Phe Gly Pro Gln His Asn Arg 
        115                 120                 125             


His Cys Leu Leu Thr Cys Glu Glu Cys Lys Ile Lys His Gly Leu Ser 
    130                 135                 140                 


Glu Lys Gly Asp Ser Gln Pro Ser Ala Ser 
145                 150                 


<210>  3161
<211>  373
<212>  PRT
<213>  homo sapiens

<400>  3161

Met Ala Ser Glu Leu Ala Met Ser Asn Ser Asp Leu Pro Thr Ser Pro 
1               5                   10                  15      


Leu Ala Met Glu Tyr Val Asn Asp Phe Asp Leu Met Lys Phe Glu Val 
            20                  25                  30          


Lys Lys Glu Pro Val Glu Thr Asp Arg Ile Ile Ser Gln Cys Gly Arg 
        35                  40                  45              


Leu Ile Ala Gly Gly Ser Leu Ser Ser Thr Pro Met Ser Thr Pro Cys 
    50                  55                  60                  


Ser Ser Val Pro Pro Ser Pro Ser Phe Ser Ala Pro Ser Pro Gly Ser 
65                  70                  75                  80  


Gly Ser Glu Gln Lys Ala His Leu Glu Asp Tyr Tyr Trp Met Thr Gly 
                85                  90                  95      


Tyr Pro Gln Gln Leu Asn Pro Glu Ala Leu Gly Phe Ser Pro Glu Asp 
            100                 105                 110         


Ala Val Glu Ala Leu Ile Ser Asn Ser His Gln Leu Gln Gly Gly Phe 
        115                 120                 125             


Asp Gly Tyr Ala Arg Gly Ala Gln Gln Leu Ala Ala Ala Ala Gly Ala 
    130                 135                 140                 


Gly Ala Gly Ala Ser Leu Gly Gly Ser Gly Glu Glu Met Gly Pro Ala 
145                 150                 155                 160 


Ala Ala Val Val Ser Ala Val Ile Ala Ala Ala Ala Ala Gln Ser Gly 
                165                 170                 175     


Ala Gly Pro His Tyr His His His His His His Ala Ala Gly His His 
            180                 185                 190         


His His Pro Thr Ala Gly Ala Pro Gly Ala Ala Gly Ser Ala Ala Ala 
        195                 200                 205             


Ser Ala Gly Gly Ala Gly Gly Ala Gly Gly Gly Gly Pro Ala Ser Ala 
    210                 215                 220                 


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Ala 
225                 230                 235                 240 


Gly Ala Gly Gly Ala Leu His Pro His His Ala Ala Gly Gly Leu His 
                245                 250                 255     


Phe Asp Asp Arg Phe Ser Asp Glu Gln Leu Val Thr Met Ser Val Arg 
            260                 265                 270         


Glu Leu Asn Arg Gln Leu Arg Gly Val Ser Lys Glu Glu Val Ile Arg 
        275                 280                 285             


Leu Lys Gln Lys Arg Arg Thr Leu Lys Asn Arg Gly Tyr Ala Gln Ser 
    290                 295                 300                 


Cys Arg Phe Lys Arg Val Gln Gln Arg His Val Leu Glu Ser Glu Lys 
305                 310                 315                 320 


Asn Gln Leu Leu Gln Gln Val Asp His Leu Lys Gln Glu Ile Ser Arg 
                325                 330                 335     


Leu Val Arg Glu Arg Asp Ala Tyr Lys Glu Lys Tyr Glu Lys Leu Val 
            340                 345                 350         


Ser Ser Gly Phe Arg Glu Asn Gly Ser Ser Ser Asp Asn Pro Ser Ser 
        355                 360                 365             


Pro Glu Phe Phe Met 
    370             


<210>  3162
<211>  164
<212>  PRT
<213>  homo sapiens

<400>  3162

Met Ser Val Asp Pro Leu Ser Ser Lys Ala Leu Lys Ile Lys Arg Glu 
1               5                   10                  15      


Leu Ser Glu Asn Thr Pro His Leu Ser Asp Glu Ala Leu Met Gly Leu 
            20                  25                  30          


Ser Val Arg Glu Leu Asn Arg His Leu Arg Gly Leu Ser Ala Glu Glu 
        35                  40                  45              


Val Thr Arg Leu Lys Gln Arg Arg Arg Thr Leu Lys Asn Arg Gly Tyr 
    50                  55                  60                  


Ala Ala Ser Cys Arg Val Lys Arg Val Cys Gln Lys Glu Glu Leu Gln 
65                  70                  75                  80  


Lys Gln Lys Ser Glu Leu Glu Arg Glu Val Asp Lys Leu Ala Arg Glu 
                85                  90                  95      


Asn Ala Ala Met Arg Leu Glu Leu Asp Ala Leu Arg Gly Lys Cys Glu 
            100                 105                 110         


Ala Leu Gln Gly Phe Ala Arg Ser Val Ala Ala Ala Arg Gly Pro Ala 
        115                 120                 125             


Thr Leu Val Ala Pro Ala Ser Val Ile Thr Ile Val Lys Ser Thr Pro 
    130                 135                 140                 


Gly Ser Gly Ser Gly Pro Ala His Gly Pro Asp Pro Ala His Gly Pro 
145                 150                 155                 160 


Ala Ser Cys Ser 
                


<210>  3163
<211>  164
<212>  PRT
<213>  homo sapiens

<400>  3163

Met Ser Val Asp Pro Leu Ser Ser Lys Ala Leu Lys Ile Lys Arg Glu 
1               5                   10                  15      


Leu Ser Glu Asn Thr Pro His Leu Ser Asp Glu Ala Leu Met Gly Leu 
            20                  25                  30          


Ser Val Arg Glu Leu Asn Arg His Leu Arg Gly Leu Ser Ala Glu Glu 
        35                  40                  45              


Val Thr Arg Leu Lys Gln Arg Arg Arg Thr Leu Lys Asn Arg Gly Tyr 
    50                  55                  60                  


Ala Ala Ser Cys Arg Val Lys Arg Val Cys Gln Lys Glu Glu Leu Gln 
65                  70                  75                  80  


Lys Gln Lys Ser Glu Leu Glu Arg Glu Val Asp Lys Leu Ala Arg Glu 
                85                  90                  95      


Asn Ala Ala Met Arg Leu Glu Leu Asp Ala Leu Arg Gly Lys Cys Glu 
            100                 105                 110         


Ala Leu Gln Gly Phe Ala Arg Ser Val Ala Ala Ala Arg Gly Pro Ala 
        115                 120                 125             


Thr Leu Val Ala Pro Ala Ser Val Ile Thr Ile Val Lys Ser Thr Pro 
    130                 135                 140                 


Gly Ser Gly Ser Gly Pro Ala His Gly Pro Asp Pro Ala His Gly Pro 
145                 150                 155                 160 


Ala Ser Cys Ser 
                


<210>  3164
<211>  1089
<212>  PRT
<213>  homo sapiens

<400>  3164

Met Gly Thr Ser His Pro Ala Phe Leu Val Leu Gly Cys Leu Leu Thr 
1               5                   10                  15      


Gly Leu Ser Leu Ile Leu Cys Gln Leu Ser Leu Pro Ser Ile Leu Pro 
            20                  25                  30          


Asn Glu Asn Glu Lys Val Val Gln Leu Asn Ser Ser Phe Ser Leu Arg 
        35                  40                  45              


Cys Phe Gly Glu Ser Glu Val Ser Trp Gln Tyr Pro Met Ser Glu Glu 
    50                  55                  60                  


Glu Ser Ser Asp Val Glu Ile Arg Asn Glu Glu Asn Asn Ser Gly Leu 
65                  70                  75                  80  


Phe Val Thr Val Leu Glu Val Ser Ser Ala Ser Ala Ala His Thr Gly 
                85                  90                  95      


Leu Tyr Thr Cys Tyr Tyr Asn His Thr Gln Thr Glu Glu Asn Glu Leu 
            100                 105                 110         


Glu Gly Arg His Ile Tyr Ile Tyr Val Pro Asp Pro Asp Val Ala Phe 
        115                 120                 125             


Val Pro Leu Gly Met Thr Asp Tyr Leu Val Ile Val Glu Asp Asp Asp 
    130                 135                 140                 


Ser Ala Ile Ile Pro Cys Arg Thr Thr Asp Pro Glu Thr Pro Val Thr 
145                 150                 155                 160 


Leu His Asn Ser Glu Gly Val Val Pro Ala Ser Tyr Asp Ser Arg Gln 
                165                 170                 175     


Gly Phe Asn Gly Thr Phe Thr Val Gly Pro Tyr Ile Cys Glu Ala Thr 
            180                 185                 190         


Val Lys Gly Lys Lys Phe Gln Thr Ile Pro Phe Asn Val Tyr Ala Leu 
        195                 200                 205             


Lys Ala Thr Ser Glu Leu Asp Leu Glu Met Glu Ala Leu Lys Thr Val 
    210                 215                 220                 


Tyr Lys Ser Gly Glu Thr Ile Val Val Thr Cys Ala Val Phe Asn Asn 
225                 230                 235                 240 


Glu Val Val Asp Leu Gln Trp Thr Tyr Pro Gly Glu Val Lys Gly Lys 
                245                 250                 255     


Gly Ile Thr Met Leu Glu Glu Ile Lys Val Pro Ser Ile Lys Leu Val 
            260                 265                 270         


Tyr Thr Leu Thr Val Pro Glu Ala Thr Val Lys Asp Ser Gly Asp Tyr 
        275                 280                 285             


Glu Cys Ala Ala Arg Gln Ala Thr Arg Glu Val Lys Glu Met Lys Lys 
    290                 295                 300                 


Val Thr Ile Ser Val His Glu Lys Gly Phe Ile Glu Ile Lys Pro Thr 
305                 310                 315                 320 


Phe Ser Gln Leu Glu Ala Val Asn Leu His Glu Val Lys His Phe Val 
                325                 330                 335     


Val Glu Val Arg Ala Tyr Pro Pro Pro Arg Ile Ser Trp Leu Lys Asn 
            340                 345                 350         


Asn Leu Thr Leu Ile Glu Asn Leu Thr Glu Ile Thr Thr Asp Val Glu 
        355                 360                 365             


Lys Ile Gln Glu Ile Arg Tyr Arg Ser Lys Leu Lys Leu Ile Arg Ala 
    370                 375                 380                 


Lys Glu Glu Asp Ser Gly His Tyr Thr Ile Val Ala Gln Asn Glu Asp 
385                 390                 395                 400 


Ala Val Lys Ser Tyr Thr Phe Glu Leu Leu Thr Gln Val Pro Ser Ser 
                405                 410                 415     


Ile Leu Asp Leu Val Asp Asp His His Gly Ser Thr Gly Gly Gln Thr 
            420                 425                 430         


Val Arg Cys Thr Ala Glu Gly Thr Pro Leu Pro Asp Ile Glu Trp Met 
        435                 440                 445             


Ile Cys Lys Asp Ile Lys Lys Cys Asn Asn Glu Thr Ser Trp Thr Ile 
    450                 455                 460                 


Leu Ala Asn Asn Val Ser Asn Ile Ile Thr Glu Ile His Ser Arg Asp 
465                 470                 475                 480 


Arg Ser Thr Val Glu Gly Arg Val Thr Phe Ala Lys Val Glu Glu Thr 
                485                 490                 495     


Ile Ala Val Arg Cys Leu Ala Lys Asn Leu Leu Gly Ala Glu Asn Arg 
            500                 505                 510         


Glu Leu Lys Leu Val Ala Pro Thr Leu Arg Ser Glu Leu Thr Val Ala 
        515                 520                 525             


Ala Ala Val Leu Val Leu Leu Val Ile Val Ile Ile Ser Leu Ile Val 
    530                 535                 540                 


Leu Val Val Ile Trp Lys Gln Lys Pro Arg Tyr Glu Ile Arg Trp Arg 
545                 550                 555                 560 


Val Ile Glu Ser Ile Ser Pro Asp Gly His Glu Tyr Ile Tyr Val Asp 
                565                 570                 575     


Pro Met Gln Leu Pro Tyr Asp Ser Arg Trp Glu Phe Pro Arg Asp Gly 
            580                 585                 590         


Leu Val Leu Gly Arg Val Leu Gly Ser Gly Ala Phe Gly Lys Val Val 
        595                 600                 605             


Glu Gly Thr Ala Tyr Gly Leu Ser Arg Ser Gln Pro Val Met Lys Val 
    610                 615                 620                 


Ala Val Lys Met Leu Lys Pro Thr Ala Arg Ser Ser Glu Lys Gln Ala 
625                 630                 635                 640 


Leu Met Ser Glu Leu Lys Ile Met Thr His Leu Gly Pro His Leu Asn 
                645                 650                 655     


Ile Val Asn Leu Leu Gly Ala Cys Thr Lys Ser Gly Pro Ile Tyr Ile 
            660                 665                 670         


Ile Thr Glu Tyr Cys Phe Tyr Gly Asp Leu Val Asn Tyr Leu His Lys 
        675                 680                 685             


Asn Arg Asp Ser Phe Leu Ser His His Pro Glu Lys Pro Lys Lys Glu 
    690                 695                 700                 


Leu Asp Ile Phe Gly Leu Asn Pro Ala Asp Glu Ser Thr Arg Ser Tyr 
705                 710                 715                 720 


Val Ile Leu Ser Phe Glu Asn Asn Gly Asp Tyr Met Asp Met Lys Gln 
                725                 730                 735     


Ala Asp Thr Thr Gln Tyr Val Pro Met Leu Glu Arg Lys Glu Val Ser 
            740                 745                 750         


Lys Tyr Ser Asp Ile Gln Arg Ser Leu Tyr Asp Arg Pro Ala Ser Tyr 
        755                 760                 765             


Lys Lys Lys Ser Met Leu Asp Ser Glu Val Lys Asn Leu Leu Ser Asp 
    770                 775                 780                 


Asp Asn Ser Glu Gly Leu Thr Leu Leu Asp Leu Leu Ser Phe Thr Tyr 
785                 790                 795                 800 


Gln Val Ala Arg Gly Met Glu Phe Leu Ala Ser Lys Asn Cys Val His 
                805                 810                 815     


Arg Asp Leu Ala Ala Arg Asn Val Leu Leu Ala Gln Gly Lys Ile Val 
            820                 825                 830         


Lys Ile Cys Asp Phe Gly Leu Ala Arg Asp Ile Met His Asp Ser Asn 
        835                 840                 845             


Tyr Val Ser Lys Gly Ser Thr Phe Leu Pro Val Lys Trp Met Ala Pro 
    850                 855                 860                 


Glu Ser Ile Phe Asp Asn Leu Tyr Thr Thr Leu Ser Asp Val Trp Ser 
865                 870                 875                 880 


Tyr Gly Ile Leu Leu Trp Glu Ile Phe Ser Leu Gly Gly Thr Pro Tyr 
                885                 890                 895     


Pro Gly Met Met Val Asp Ser Thr Phe Tyr Asn Lys Ile Lys Ser Gly 
            900                 905                 910         


Tyr Arg Met Ala Lys Pro Asp His Ala Thr Ser Glu Val Tyr Glu Ile 
        915                 920                 925             


Met Val Lys Cys Trp Asn Ser Glu Pro Glu Lys Arg Pro Ser Phe Tyr 
    930                 935                 940                 


His Leu Ser Glu Ile Val Glu Asn Leu Leu Pro Gly Gln Tyr Lys Lys 
945                 950                 955                 960 


Ser Tyr Glu Lys Ile His Leu Asp Phe Leu Lys Ser Asp His Pro Ala 
                965                 970                 975     


Val Ala Arg Met Arg Val Asp Ser Asp Asn Ala Tyr Ile Gly Val Thr 
            980                 985                 990         


Tyr Lys Asn Glu Glu Asp Lys Leu  Lys Asp Trp Glu Gly  Gly Leu Asp 
        995                 1000                 1005             


Glu Gln  Arg Leu Ser Ala Asp  Ser Gly Tyr Ile Ile  Pro Leu Pro 
    1010                 1015                 1020             


Asp Ile  Asp Pro Val Pro Glu  Glu Glu Asp Leu Gly  Lys Arg Asn 
    1025                 1030                 1035             


Arg His  Ser Ser Gln Thr Ser  Glu Glu Ser Ala Ile  Glu Thr Gly 
    1040                 1045                 1050             


Ser Ser  Ser Ser Thr Phe Ile  Lys Arg Glu Asp Glu  Thr Ile Glu 
    1055                 1060                 1065             


Asp Ile  Asp Met Met Asp Asp  Ile Gly Ile Asp Ser  Ser Asp Leu 
    1070                 1075                 1080             


Val Glu  Asp Ser Phe Leu 
    1085                 


<210>  3165
<211>  673
<212>  PRT
<213>  homo sapiens

<400>  3165

Met Asp Leu Thr Lys Met Gly Met Ile Gln Leu Gln Asn Pro Ser His 
1               5                   10                  15      


Pro Thr Gly Leu Leu Cys Lys Ala Asn Gln Met Arg Leu Ala Gly Thr 
            20                  25                  30          


Leu Cys Asp Val Val Ile Met Val Asp Ser Gln Glu Phe His Ala His 
        35                  40                  45              


Arg Thr Val Leu Ala Cys Thr Ser Lys Met Phe Glu Ile Leu Phe His 
    50                  55                  60                  


Arg Asn Ser Gln His Tyr Thr Leu Asp Phe Leu Ser Pro Lys Thr Phe 
65                  70                  75                  80  


Gln Gln Ile Leu Glu Tyr Ala Tyr Thr Ala Thr Leu Gln Ala Lys Ala 
                85                  90                  95      


Glu Asp Leu Asp Asp Leu Leu Tyr Ala Ala Glu Ile Leu Glu Ile Glu 
            100                 105                 110         


Tyr Leu Glu Glu Gln Cys Leu Lys Met Leu Glu Thr Ile Gln Ala Ser 
        115                 120                 125             


Asp Asp Asn Asp Thr Glu Ala Thr Met Ala Asp Gly Gly Ala Glu Glu 
    130                 135                 140                 


Glu Glu Asp Arg Lys Ala Arg Tyr Leu Lys Asn Ile Phe Ile Ser Lys 
145                 150                 155                 160 


His Ser Ser Glu Glu Ser Gly Tyr Ala Ser Val Ala Gly Gln Ser Leu 
                165                 170                 175     


Pro Gly Pro Met Val Asp Gln Ser Pro Ser Val Ser Thr Ser Phe Gly 
            180                 185                 190         


Leu Ser Ala Met Ser Pro Thr Lys Ala Ala Val Asp Ser Leu Met Thr 
        195                 200                 205             


Ile Gly Gln Ser Leu Leu Gln Gly Thr Leu Gln Pro Pro Ala Gly Pro 
    210                 215                 220                 


Glu Glu Pro Thr Leu Ala Gly Gly Gly Arg His Pro Gly Val Ala Glu 
225                 230                 235                 240 


Val Lys Thr Glu Met Met Gln Val Asp Glu Val Pro Ser Gln Asp Ser 
                245                 250                 255     


Pro Gly Ala Ala Glu Ser Ser Ile Ser Gly Gly Met Gly Asp Lys Val 
            260                 265                 270         


Glu Glu Arg Gly Lys Glu Gly Pro Gly Thr Pro Thr Arg Ser Ser Val 
        275                 280                 285             


Ile Thr Ser Ala Arg Glu Leu His Tyr Gly Arg Glu Glu Ser Ala Glu 
    290                 295                 300                 


Gln Val Pro Pro Pro Ala Glu Ala Gly Gln Ala Pro Thr Gly Arg Pro 
305                 310                 315                 320 


Glu His Pro Ala Pro Pro Pro Glu Lys His Leu Gly Ile Tyr Ser Val 
                325                 330                 335     


Leu Pro Asn His Lys Ala Asp Ala Val Leu Ser Met Pro Ser Ser Val 
            340                 345                 350         


Thr Ser Gly Leu His Val Gln Pro Ala Leu Ala Val Ser Met Asp Phe 
        355                 360                 365             


Ser Thr Tyr Gly Gly Leu Leu Pro Gln Gly Phe Ile Gln Arg Glu Leu 
    370                 375                 380                 


Phe Ser Lys Leu Gly Glu Leu Ala Val Gly Met Lys Ser Glu Ser Arg 
385                 390                 395                 400 


Thr Ile Gly Glu Gln Cys Ser Val Cys Gly Val Glu Leu Pro Asp Asn 
                405                 410                 415     


Glu Ala Val Glu Gln His Arg Lys Leu His Ser Gly Met Lys Thr Tyr 
            420                 425                 430         


Gly Cys Glu Leu Cys Gly Lys Arg Phe Leu Asp Ser Leu Arg Leu Arg 
        435                 440                 445             


Met His Leu Leu Ala His Ser Ala Gly Ala Lys Ala Phe Val Cys Asp 
    450                 455                 460                 


Gln Cys Gly Ala Gln Phe Ser Lys Glu Asp Ala Leu Glu Thr His Arg 
465                 470                 475                 480 


Gln Thr His Thr Gly Thr Asp Met Ala Val Phe Cys Leu Leu Cys Gly 
                485                 490                 495     


Lys Arg Phe Gln Ala Gln Ser Ala Leu Gln Gln His Met Glu Val His 
            500                 505                 510         


Ala Gly Val Arg Ser Tyr Ile Cys Ser Glu Cys Asn Arg Thr Phe Pro 
        515                 520                 525             


Ser His Thr Ala Leu Lys Arg His Leu Arg Ser His Thr Gly Asp His 
    530                 535                 540                 


Pro Tyr Glu Cys Glu Phe Cys Gly Ser Cys Phe Arg Asp Glu Ser Thr 
545                 550                 555                 560 


Leu Lys Ser His Lys Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys 
                565                 570                 575     


Asn Gly Cys Gly Lys Lys Phe Ser Leu Lys His Gln Leu Glu Thr His 
            580                 585                 590         


Tyr Arg Val His Thr Gly Glu Lys Pro Phe Glu Cys Lys Leu Cys His 
        595                 600                 605             


Gln Arg Ser Arg Asp Tyr Ser Ala Met Ile Lys His Leu Arg Thr His 
    610                 615                 620                 


Asn Gly Ala Ser Pro Tyr Gln Cys Thr Ile Cys Thr Glu Tyr Cys Pro 
625                 630                 635                 640 


Ser Leu Ser Ser Met Gln Lys His Met Lys Gly His Lys Pro Glu Glu 
                645                 650                 655     


Ile Pro Pro Asp Trp Arg Ile Glu Lys Thr Tyr Leu Tyr Leu Cys Tyr 
            660                 665                 670         


Val 
    


<210>  3166
<211>  550
<212>  PRT
<213>  homo sapiens

<400>  3166

Met Glu Glu Met Glu Glu Glu Leu Lys Cys Pro Val Cys Gly Ser Phe 
1               5                   10                  15      


Tyr Arg Glu Pro Ile Ile Leu Pro Cys Ser His Asn Leu Cys Gln Ala 
            20                  25                  30          


Cys Ala Arg Asn Ile Leu Val Gln Thr Pro Glu Ser Glu Ser Pro Gln 
        35                  40                  45              


Ser His Arg Ala Ala Gly Ser Gly Val Ser Asp Tyr Asp Tyr Leu Asp 
    50                  55                  60                  


Leu Asp Lys Met Ser Leu Tyr Ser Glu Ala Asp Ser Gly Tyr Gly Ser 
65                  70                  75                  80  


Tyr Gly Gly Phe Ala Ser Ala Pro Thr Thr Pro Cys Gln Lys Ser Pro 
                85                  90                  95      


Asn Gly Val Arg Val Phe Pro Pro Ala Met Pro Pro Pro Ala Thr His 
            100                 105                 110         


Leu Ser Pro Ala Leu Ala Pro Val Pro Arg Asn Ser Cys Ile Thr Cys 
        115                 120                 125             


Pro Gln Cys His Arg Ser Leu Ile Leu Asp Asp Arg Gly Leu Arg Gly 
    130                 135                 140                 


Phe Pro Lys Asn Arg Val Leu Glu Gly Val Ile Asp Arg Tyr Gln Gln 
145                 150                 155                 160 


Ser Lys Ala Ala Ala Leu Lys Cys Gln Leu Cys Glu Lys Ala Pro Lys 
                165                 170                 175     


Glu Ala Thr Val Met Cys Glu Gln Cys Asp Val Phe Tyr Cys Asp Pro 
            180                 185                 190         


Cys Arg Leu Arg Cys His Pro Pro Arg Gly Pro Leu Ala Lys His Arg 
        195                 200                 205             


Leu Val Pro Pro Ala Gln Gly Arg Val Ser Arg Arg Leu Ser Pro Arg 
    210                 215                 220                 


Lys Val Ser Thr Cys Thr Asp His Glu Leu Glu Asn His Ser Met Tyr 
225                 230                 235                 240 


Cys Val Gln Cys Lys Met Pro Val Cys Tyr Gln Cys Leu Glu Glu Gly 
                245                 250                 255     


Lys His Ser Ser His Glu Val Lys Ala Leu Gly Ala Met Trp Lys Leu 
            260                 265                 270         


His Lys Ser Gln Leu Ser Gln Ala Leu Asn Gly Leu Ser Asp Arg Ala 
        275                 280                 285             


Lys Glu Ala Lys Glu Phe Leu Val Gln Leu Arg Asn Met Val Gln Gln 
    290                 295                 300                 


Ile Gln Glu Asn Ser Val Glu Phe Glu Ala Cys Leu Val Ala Gln Cys 
305                 310                 315                 320 


Asp Ala Leu Ile Asp Ala Leu Asn Arg Arg Lys Ala Gln Leu Leu Ala 
                325                 330                 335     


Arg Val Asn Lys Glu His Glu His Lys Leu Lys Val Val Arg Asp Gln 
            340                 345                 350         


Ile Ser His Cys Thr Val Lys Leu Arg Gln Thr Thr Gly Leu Met Glu 
        355                 360                 365             


Tyr Cys Leu Glu Val Ile Lys Glu Asn Asp Pro Ser Gly Phe Leu Gln 
    370                 375                 380                 


Ile Ser Asp Ala Leu Ile Arg Arg Val His Leu Thr Glu Asp Gln Trp 
385                 390                 395                 400 


Gly Lys Gly Thr Leu Thr Pro Arg Met Thr Thr Asp Phe Asp Leu Ser 
                405                 410                 415     


Leu Asp Asn Ser Pro Leu Leu Gln Ser Ile His Gln Leu Asp Phe Val 
            420                 425                 430         


Gln Val Lys Ala Ser Ser Pro Val Pro Ala Thr Pro Ile Leu Gln Leu 
        435                 440                 445             


Glu Glu Cys Cys Thr His Asn Asn Ser Ala Thr Leu Ser Trp Lys Gln 
    450                 455                 460                 


Pro Pro Leu Ser Thr Val Pro Ala Asp Gly Tyr Ile Leu Glu Leu Asp 
465                 470                 475                 480 


Asp Gly Asn Gly Gly Gln Phe Arg Glu Val Tyr Val Gly Lys Glu Thr 
                485                 490                 495     


Met Cys Thr Val Asp Gly Leu His Phe Asn Ser Thr Tyr Asn Ala Arg 
            500                 505                 510         


Val Lys Ala Phe Asn Lys Thr Gly Val Ser Pro Tyr Ser Lys Thr Leu 
        515                 520                 525             


Val Leu Gln Thr Ser Glu Gly Lys Ala Leu Gln Gln Tyr Pro Ser Glu 
    530                 535                 540                 


Arg Glu Leu Arg Gly Ile 
545                 550 


<210>  3167
<211>  847
<212>  PRT
<213>  homo sapiens

<400>  3167

Met Glu Pro Trp Lys Gln Cys Ala Gln Trp Leu Ile His Cys Lys Val 
1               5                   10                  15      


Leu Pro Thr Asn His Arg Val Thr Trp Asp Ser Ala Gln Val Phe Asp 
            20                  25                  30          


Leu Ala Gln Thr Leu Arg Asp Gly Val Leu Leu Cys Gln Leu Leu Asn 
        35                  40                  45              


Asn Leu Arg Ala His Ser Ile Asn Leu Lys Glu Ile Asn Leu Arg Pro 
    50                  55                  60                  


Gln Met Ser Gln Phe Leu Cys Leu Lys Asn Ile Arg Thr Phe Leu Thr 
65                  70                  75                  80  


Ala Cys Cys Glu Thr Phe Gly Met Arg Lys Ser Glu Leu Phe Glu Ala 
                85                  90                  95      


Phe Asp Leu Phe Asp Val Arg Asp Phe Gly Lys Val Ile Glu Thr Leu 
            100                 105                 110         


Ser Arg Leu Ser Arg Thr Pro Ile Ala Leu Ala Thr Gly Ile Arg Pro 
        115                 120                 125             


Phe Pro Thr Glu Glu Ser Ile Asn Asp Glu Asp Ile Tyr Lys Gly Leu 
    130                 135                 140                 


Pro Asp Leu Ile Asp Glu Thr Leu Val Glu Asp Glu Glu Asp Leu Tyr 
145                 150                 155                 160 


Asp Cys Val Tyr Gly Glu Asp Glu Gly Gly Glu Val Tyr Glu Asp Leu 
                165                 170                 175     


Met Lys Ala Glu Glu Ala His Gln Pro Lys Cys Pro Glu Asn Asp Ile 
            180                 185                 190         


Arg Ser Cys Cys Leu Ala Glu Ile Lys Gln Thr Glu Glu Lys Tyr Thr 
        195                 200                 205             


Glu Thr Leu Glu Ser Ile Glu Lys Tyr Phe Met Ala Pro Leu Lys Arg 
    210                 215                 220                 


Phe Leu Thr Ala Ala Glu Phe Asp Ser Val Phe Ile Asn Ile Pro Glu 
225                 230                 235                 240 


Leu Val Lys Leu His Arg Asn Leu Met Gln Glu Ile His Asp Ser Ile 
                245                 250                 255     


Val Asn Lys Asn Asp Gln Asn Leu Tyr Gln Val Phe Ile Asn Tyr Lys 
            260                 265                 270         


Glu Arg Leu Val Ile Tyr Gly Gln Tyr Cys Ser Gly Val Glu Ser Ala 
        275                 280                 285             


Ile Ser Ser Leu Asp Tyr Ile Ser Lys Thr Lys Glu Asp Val Lys Leu 
    290                 295                 300                 


Lys Leu Glu Glu Cys Ser Lys Arg Ala Asn Asn Gly Lys Phe Thr Leu 
305                 310                 315                 320 


Arg Asp Leu Leu Val Val Pro Met Gln Arg Val Leu Lys Tyr His Leu 
                325                 330                 335     


Leu Leu Gln Glu Leu Val Lys His Thr Thr Asp Pro Thr Glu Lys Ala 
            340                 345                 350         


Asn Leu Lys Leu Ala Leu Asp Ala Met Lys Asp Leu Ala Gln Tyr Val 
        355                 360                 365             


Asn Glu Val Lys Arg Asp Asn Glu Thr Leu Arg Glu Ile Lys Gln Phe 
    370                 375                 380                 


Gln Leu Ser Ile Glu Asn Leu Asn Gln Pro Val Leu Leu Phe Gly Arg 
385                 390                 395                 400 


Pro Gln Gly Asp Gly Glu Ile Arg Ile Thr Thr Leu Asp Lys His Thr 
                405                 410                 415     


Lys Gln Glu Arg His Ile Phe Leu Phe Asp Leu Ala Val Ile Val Cys 
            420                 425                 430         


Lys Arg Lys Gly Asp Asn Tyr Glu Met Lys Glu Ile Ile Asp Leu Gln 
        435                 440                 445             


Gln Tyr Lys Ile Ala Asn Asn Pro Thr Thr Asp Lys Glu Asn Lys Lys 
    450                 455                 460                 


Trp Ser Tyr Gly Phe Tyr Leu Ile His Thr Gln Gly Gln Asn Gly Leu 
465                 470                 475                 480 


Glu Phe Tyr Cys Lys Thr Lys Asp Leu Lys Lys Lys Trp Leu Glu Gln 
                485                 490                 495     


Phe Glu Met Ala Leu Ser Asn Ile Arg Pro Asp Tyr Ala Asp Ser Asn 
            500                 505                 510         


Phe His Asp Phe Lys Met His Thr Phe Thr Arg Val Thr Ser Cys Lys 
        515                 520                 525             


Val Cys Gln Met Leu Leu Arg Gly Thr Phe Tyr Gln Gly Tyr Leu Cys 
    530                 535                 540                 


Phe Lys Cys Gly Ala Arg Ala His Lys Glu Cys Leu Gly Arg Val Asp 
545                 550                 555                 560 


Asn Cys Gly Arg Val Asn Ser Gly Glu Gln Gly Thr Leu Lys Leu Pro 
                565                 570                 575     


Glu Lys Arg Thr Asn Gly Leu Arg Arg Thr Pro Lys Gln Val Asp Pro 
            580                 585                 590         


Gly Leu Pro Lys Met Gln Val Ile Arg Asn Tyr Ser Gly Thr Pro Pro 
        595                 600                 605             


Pro Ala Leu His Glu Gly Pro Pro Leu Gln Leu Gln Ala Gly Asp Thr 
    610                 615                 620                 


Val Glu Leu Leu Lys Gly Asp Ala His Ser Leu Phe Trp Gln Gly Arg 
625                 630                 635                 640 


Asn Leu Ala Ser Gly Glu Val Gly Phe Phe Pro Ser Asp Ala Val Lys 
                645                 650                 655     


Pro Cys Pro Cys Val Pro Lys Pro Val Asp Tyr Ser Cys Gln Pro Trp 
            660                 665                 670         


Tyr Ala Gly Ala Met Glu Arg Leu Gln Ala Glu Thr Glu Leu Ile Asn 
        675                 680                 685             


Arg Val Asn Ser Thr Tyr Leu Val Arg His Arg Thr Lys Glu Ser Gly 
    690                 695                 700                 


Glu Tyr Ala Ile Ser Ile Lys Tyr Asn Asn Glu Ala Lys His Ile Lys 
705                 710                 715                 720 


Ile Leu Thr Arg Asp Gly Phe Phe His Ile Ala Glu Asn Arg Lys Phe 
                725                 730                 735     


Lys Ser Leu Met Glu Leu Val Glu Tyr Tyr Lys His His Ser Leu Lys 
            740                 745                 750         


Glu Gly Phe Arg Thr Leu Asp Thr Thr Leu Gln Phe Pro Tyr Lys Glu 
        755                 760                 765             


Pro Glu His Ser Ala Gly Gln Arg Gly Asn Arg Ala Gly Asn Ser Leu 
    770                 775                 780                 


Leu Ser Pro Lys Val Leu Gly Ile Ala Ile Ala Arg Tyr Asp Phe Cys 
785                 790                 795                 800 


Ala Arg Asp Met Arg Glu Leu Ser Leu Leu Lys Gly Asp Val Val Lys 
                805                 810                 815     


Ile Tyr Thr Lys Met Ser Ala Asn Gly Trp Trp Arg Gly Glu Val Asn 
            820                 825                 830         


Gly Arg Val Gly Trp Phe Pro Ser Thr Tyr Val Glu Glu Asp Glu 
        835                 840                 845         


<210>  3168
<211>  581
<212>  PRT
<213>  homo sapiens

<400>  3168

Met Trp Gly Arg Thr Ala Arg Arg Arg Cys Pro Arg Glu Leu Arg Arg 
1               5                   10                  15      


Gly Arg Glu Ala Leu Leu Val Leu Leu Ala Leu Leu Ala Leu Ala Gly 
            20                  25                  30          


Leu Gly Ser Val Leu Arg Ala Gln Arg Gly Ala Gly Ala Gly Ala Ala 
        35                  40                  45              


Glu Pro Gly Pro Pro Arg Thr Pro Arg Pro Gly Arg Arg Glu Pro Val 
    50                  55                  60                  


Met Pro Arg Pro Pro Val Pro Ala Asn Ala Leu Gly Ala Arg Gly Glu 
65                  70                  75                  80  


Ala Val Arg Leu Gln Leu Gln Gly Glu Glu Leu Arg Leu Gln Glu Glu 
                85                  90                  95      


Ser Val Arg Leu His Gln Ile Asn Ile Tyr Leu Ser Asp Arg Ile Ser 
            100                 105                 110         


Leu His Arg Arg Leu Pro Glu Arg Trp Asn Pro Leu Cys Lys Glu Lys 
        115                 120                 125             


Lys Tyr Asp Tyr Asp Asn Leu Pro Arg Thr Ser Val Ile Ile Ala Phe 
    130                 135                 140                 


Tyr Asn Glu Ala Trp Ser Thr Leu Leu Arg Thr Val Tyr Ser Val Leu 
145                 150                 155                 160 


Glu Thr Ser Pro Asp Ile Leu Leu Glu Glu Val Ile Leu Val Asp Asp 
                165                 170                 175     


Tyr Ser Asp Arg Glu His Leu Lys Glu Arg Leu Ala Asn Glu Leu Ser 
            180                 185                 190         


Gly Leu Pro Lys Val Arg Leu Ile Arg Ala Asn Lys Arg Glu Gly Leu 
        195                 200                 205             


Val Arg Ala Arg Leu Leu Gly Ala Ser Ala Ala Arg Gly Asp Val Leu 
    210                 215                 220                 


Thr Phe Leu Asp Cys His Cys Glu Cys His Glu Gly Trp Leu Glu Pro 
225                 230                 235                 240 


Leu Leu Gln Arg Ile His Glu Glu Glu Ser Ala Val Val Cys Pro Val 
                245                 250                 255     


Ile Asp Val Ile Asp Trp Asn Thr Phe Glu Tyr Leu Gly Asn Ser Gly 
            260                 265                 270         


Glu Pro Gln Ile Gly Gly Phe Asp Trp Arg Leu Val Phe Thr Trp His 
        275                 280                 285             


Thr Val Pro Glu Arg Glu Arg Ile Arg Met Gln Ser Pro Val Asp Val 
    290                 295                 300                 


Ile Arg Ser Pro Thr Met Ala Gly Gly Leu Phe Ala Val Ser Lys Lys 
305                 310                 315                 320 


Tyr Phe Glu Tyr Leu Gly Ser Tyr Asp Thr Gly Met Glu Val Trp Gly 
                325                 330                 335     


Gly Glu Asn Leu Glu Phe Ser Phe Arg Ile Trp Gln Cys Gly Gly Val 
            340                 345                 350         


Leu Glu Thr His Pro Cys Ser His Val Gly His Val Phe Pro Lys Gln 
        355                 360                 365             


Ala Pro Tyr Ser Arg Asn Lys Ala Leu Ala Asn Ser Val Arg Ala Ala 
    370                 375                 380                 


Glu Val Trp Met Asp Glu Phe Lys Glu Leu Tyr Tyr His Arg Asn Pro 
385                 390                 395                 400 


Arg Ala Arg Leu Glu Pro Phe Gly Asp Val Thr Glu Arg Lys Gln Leu 
                405                 410                 415     


Arg Asp Lys Leu Gln Cys Lys Asp Phe Lys Trp Phe Leu Glu Thr Val 
            420                 425                 430         


Tyr Pro Glu Leu His Val Pro Glu Asp Arg Pro Gly Phe Phe Gly Met 
        435                 440                 445             


Leu Gln Asn Lys Gly Leu Thr Asp Tyr Cys Phe Asp Tyr Asn Pro Pro 
    450                 455                 460                 


Asp Glu Asn Gln Ile Val Gly His Gln Val Ile Leu Tyr Leu Cys His 
465                 470                 475                 480 


Gly Met Gly Gln Asn Gln Phe Phe Glu Tyr Thr Ser Gln Lys Glu Ile 
                485                 490                 495     


Arg Tyr Asn Thr His Gln Pro Glu Gly Cys Ile Ala Val Glu Ala Gly 
            500                 505                 510         


Met Asp Thr Leu Ile Met His Leu Cys Glu Glu Thr Ala Pro Glu Asn 
        515                 520                 525             


Gln Lys Phe Ile Leu Gln Glu Asp Gly Ser Leu Phe His Glu Gln Ser 
    530                 535                 540                 


Lys Lys Cys Val Gln Ala Ala Arg Lys Glu Ser Ser Asp Ser Phe Val 
545                 550                 555                 560 


Pro Leu Leu Arg Asp Cys Thr Asn Ser Asp His Gln Lys Trp Phe Phe 
                565                 570                 575     


Lys Glu Arg Met Leu 
            580     


<210>  3169
<211>  312
<212>  PRT
<213>  homo sapiens

<400>  3169

Met Ser Ser Ser Val Glu Gln Lys Lys Gly Pro Thr Arg Gln Arg Lys 
1               5                   10                  15      


Cys Gly Phe Cys Lys Ser Asn Arg Asp Lys Glu Cys Gly Gln Leu Leu 
            20                  25                  30          


Ile Ser Glu Asn Gln Lys Val Ala Ala His His Lys Cys Met Leu Phe 
        35                  40                  45              


Ser Ser Ala Leu Val Ser Ser His Ser Asp Asn Glu Ser Leu Gly Gly 
    50                  55                  60                  


Phe Ser Ile Glu Asp Val Gln Lys Glu Ile Lys Arg Gly Thr Lys Leu 
65                  70                  75                  80  


Met Cys Ser Leu Cys His Cys Pro Gly Ala Thr Ile Gly Cys Asp Val 
                85                  90                  95      


Lys Thr Cys His Arg Thr Tyr His Tyr His Cys Ala Leu His Asp Lys 
            100                 105                 110         


Ala Gln Ile Arg Glu Lys Pro Ser Gln Gly Ile Tyr Met Val Tyr Cys 
        115                 120                 125             


Arg Lys His Lys Lys Thr Ala His Asn Ser Glu Ala Ala Asp Leu Glu 
    130                 135                 140                 


Glu Ser Phe Asn Glu His Glu Leu Glu Pro Ser Ser Pro Lys Ser Lys 
145                 150                 155                 160 


Lys Lys Ser Arg Lys Gly Arg Pro Arg Lys Thr Asn Phe Lys Gly Leu 
                165                 170                 175     


Ser Glu Asp Thr Arg Ser Thr Ser Ser His Gly Thr Asp Glu Met Glu 
            180                 185                 190         


Ser Ser Ser Tyr Arg Asp Arg Ser Pro His Arg Ser Ser Pro Ser Asp 
        195                 200                 205             


Thr Arg Pro Lys Cys Gly Phe Cys His Val Gly Glu Glu Glu Asn Glu 
    210                 215                 220                 


Ala Arg Gly Lys Leu His Ile Phe Asn Ala Lys Lys Ala Ala Ala His 
225                 230                 235                 240 


Tyr Lys Cys Met Leu Phe Ser Ser Gly Thr Val Gln Leu Thr Thr Thr 
                245                 250                 255     


Ser Arg Ala Glu Phe Gly Asp Phe Asp Ile Lys Thr Val Leu Gln Glu 
            260                 265                 270         


Ile Lys Arg Gly Lys Arg Met Val Cys Ser Phe Tyr Ile Cys Tyr Ala 
        275                 280                 285             


Thr Leu His Leu Ile Cys Cys Phe Lys Phe Arg Val His Pro Lys Phe 
    290                 295                 300                 


Ile Gln Ser Ser Glu Asn Leu Lys 
305                 310         


<210>  3170
<211>  386
<212>  PRT
<213>  homo sapiens

<400>  3170

Met Pro Gln Leu Ser Gly Gly Gly Gly Gly Gly Gly Gly Asp Pro Glu 
1               5                   10                  15      


Leu Cys Ala Thr Asp Glu Met Ile Pro Phe Lys Asp Glu Gly Asp Pro 
            20                  25                  30          


Gln Lys Glu Lys Ile Phe Ala Glu Ile Ser His Pro Glu Glu Glu Gly 
        35                  40                  45              


Asp Leu Ala Asp Ile Lys Ser Ser Leu Val Asn Glu Ser Glu Ile Ile 
    50                  55                  60                  


Pro Ala Ser Asn Gly His Glu Val Ala Arg Gln Ala Gln Thr Ser Gln 
65                  70                  75                  80  


Glu Pro Tyr His Asp Lys Ala Arg Glu His Pro Asp Asp Gly Lys His 
                85                  90                  95      


Pro Asp Gly Gly Leu Tyr Asn Lys Gly Pro Ser Tyr Ser Ser Tyr Ser 
            100                 105                 110         


Gly Tyr Ile Met Met Pro Asn Met Asn Asn Asp Pro Tyr Met Ser Asn 
        115                 120                 125             


Gly Ser Leu Ser Pro Pro Ile Pro Arg Thr Ser Asn Lys Val Pro Val 
    130                 135                 140                 


Val Gln Pro Ser His Ala Val His Pro Leu Thr Pro Leu Ile Thr Tyr 
145                 150                 155                 160 


Ser Asp Glu His Phe Ser Pro Gly Ser His Pro Ser His Ile Pro Ser 
                165                 170                 175     


Asp Val Asn Ser Lys Gln Gly Met Ser Arg His Pro Pro Ala Pro Asp 
            180                 185                 190         


Ile Pro Thr Phe Tyr Pro Leu Ser Pro Gly Gly Val Gly Gln Ile Thr 
        195                 200                 205             


Pro Pro Leu Gly Trp Phe Ser His His Met Ile Pro Gly Pro Pro Gly 
    210                 215                 220                 


Pro His Thr Thr Gly Ile Pro His Pro Ala Ile Val Thr Pro Gln Val 
225                 230                 235                 240 


Lys Gln Glu His Pro His Thr Asp Ser Asp Leu Met His Val Lys Pro 
                245                 250                 255     


Gln His Glu Gln Arg Lys Glu Gln Glu Pro Lys Arg Pro His Ile Lys 
            260                 265                 270         


Lys Pro Leu Asn Ala Phe Met Leu Tyr Met Lys Glu Met Arg Ala Asn 
        275                 280                 285             


Val Val Ala Glu Cys Thr Leu Lys Glu Ser Ala Ala Ile Asn Gln Ile 
    290                 295                 300                 


Leu Gly Arg Arg Trp His Ala Leu Ser Arg Glu Glu Gln Ala Lys Tyr 
305                 310                 315                 320 


Tyr Glu Leu Ala Arg Lys Glu Arg Gln Leu His Met Gln Leu Tyr Pro 
                325                 330                 335     


Gly Trp Ser Ala Arg Asp Asn Tyr Gly Lys Lys Lys Lys Arg Lys Arg 
            340                 345                 350         


Glu Lys Leu Gln Glu Ser Ala Ser Gly Gly Lys Arg Ser Ser Phe Pro 
        355                 360                 365             


Thr Cys Lys Ala Lys Ala Ala Thr Pro Gly Pro Leu Leu Glu Met Glu 
    370                 375                 380                 


Ala Cys 
385     


<210>  3171
<211>  1205
<212>  PRT
<213>  homo sapiens

<400>  3171

Met Thr Asn Pro Ser Asp Arg Val Leu Pro Ala Asn Ser Met Ala Glu 
1               5                   10                  15      


Ser Arg Glu Gly Asp Phe Gly Cys Thr Val Met Glu Leu Arg Lys Leu 
            20                  25                  30          


Met Glu Leu Arg Ser Arg Asp Ala Leu Thr Gln Ile Asn Val His Tyr 
        35                  40                  45              


Gly Gly Val Gln Asn Leu Cys Ser Arg Leu Lys Thr Ser Pro Val Glu 
    50                  55                  60                  


Gly Leu Ser Gly Asn Pro Ala Asp Leu Glu Lys Arg Arg Gln Val Phe 
65                  70                  75                  80  


Gly His Asn Val Ile Pro Pro Lys Lys Pro Lys Thr Phe Leu Glu Leu 
                85                  90                  95      


Val Trp Glu Ala Leu Gln Asp Val Thr Leu Ile Ile Leu Glu Ile Ala 
            100                 105                 110         


Ala Ile Ile Ser Leu Val Leu Ser Phe Tyr Arg Pro Ala Gly Glu Glu 
        115                 120                 125             


Asn Glu Leu Cys Gly Gln Val Ala Thr Thr Pro Glu Asp Glu Asn Glu 
    130                 135                 140                 


Ala Gln Ala Gly Trp Ile Glu Gly Ala Ala Ile Leu Phe Ser Val Ile 
145                 150                 155                 160 


Ile Val Val Leu Val Thr Ala Phe Asn Asp Trp Ser Lys Glu Lys Gln 
                165                 170                 175     


Phe Arg Gly Leu Gln Cys Arg Ile Glu Gln Glu Gln Lys Phe Ser Ile 
            180                 185                 190         


Ile Arg Asn Gly Gln Leu Ile Gln Leu Pro Val Ala Glu Ile Val Val 
        195                 200                 205             


Gly Asp Ile Ala Gln Val Lys Tyr Gly Asp Leu Leu Pro Ala Asp Gly 
    210                 215                 220                 


Ile Leu Ile Gln Gly Asn Asp Leu Lys Ile Asp Glu Ser Ser Leu Thr 
225                 230                 235                 240 


Gly Glu Ser Asp His Val Lys Lys Ser Leu Asp Lys Asp Pro Met Leu 
                245                 250                 255     


Leu Ser Gly Thr His Val Met Glu Gly Ser Gly Arg Met Val Val Thr 
            260                 265                 270         


Ala Val Gly Val Asn Ser Gln Thr Gly Ile Ile Leu Thr Leu Leu Gly 
        275                 280                 285             


Val Asn Glu Asp Asp Glu Gly Glu Lys Lys Lys Lys Gly Lys Lys Gln 
    290                 295                 300                 


Gly Val Pro Glu Asn Arg Asn Lys Ala Lys Thr Gln Asp Gly Val Ala 
305                 310                 315                 320 


Leu Glu Ile Gln Pro Leu Asn Ser Gln Glu Gly Ile Asp Asn Glu Glu 
                325                 330                 335     


Lys Asp Lys Lys Ala Val Lys Val Pro Lys Lys Glu Lys Ser Val Leu 
            340                 345                 350         


Gln Gly Lys Leu Thr Arg Leu Ala Val Gln Ile Gly Lys Ala Gly Leu 
        355                 360                 365             


Leu Met Ser Ala Leu Thr Val Phe Ile Leu Ile Leu Tyr Phe Val Ile 
    370                 375                 380                 


Asp Asn Phe Val Ile Asn Arg Arg Pro Trp Leu Pro Glu Cys Thr Pro 
385                 390                 395                 400 


Ile Tyr Ile Gln Tyr Phe Val Lys Phe Phe Ile Ile Gly Ile Thr Val 
                405                 410                 415     


Leu Val Val Ala Val Pro Glu Gly Leu Pro Leu Ala Val Thr Ile Ser 
            420                 425                 430         


Leu Ala Tyr Ser Val Lys Lys Met Met Lys Asp Asn Asn Leu Val Arg 
        435                 440                 445             


His Leu Asp Ala Cys Glu Thr Met Gly Asn Ala Thr Ala Ile Cys Ser 
    450                 455                 460                 


Asp Lys Thr Gly Thr Leu Thr Met Asn Arg Met Thr Val Val Gln Ala 
465                 470                 475                 480 


Tyr Ile Gly Gly Ile His Tyr Arg Gln Ile Pro Ser Pro Asp Val Phe 
                485                 490                 495     


Leu Pro Lys Val Leu Asp Leu Ile Val Asn Gly Ile Ser Ile Asn Ser 
            500                 505                 510         


Ala Tyr Thr Ser Lys Ile Leu Pro Pro Glu Lys Glu Gly Gly Leu Pro 
        515                 520                 525             


Arg Gln Val Gly Asn Lys Thr Glu Cys Ala Leu Leu Gly Phe Val Thr 
    530                 535                 540                 


Asp Leu Lys Gln Asp Tyr Gln Ala Val Arg Asn Glu Val Pro Glu Glu 
545                 550                 555                 560 


Lys Leu Tyr Lys Val Tyr Thr Phe Asn Ser Val Arg Lys Ser Met Ser 
                565                 570                 575     


Thr Val Ile Arg Asn Pro Asn Gly Gly Phe Arg Met Tyr Ser Lys Gly 
            580                 585                 590         


Ala Ser Glu Ile Ile Leu Arg Lys Cys Asn Arg Ile Leu Asp Arg Lys 
        595                 600                 605             


Gly Glu Ala Val Pro Phe Lys Asn Lys Asp Arg Asp Asp Met Val Arg 
    610                 615                 620                 


Thr Val Ile Glu Pro Met Ala Cys Asp Gly Leu Arg Thr Ile Cys Ile 
625                 630                 635                 640 


Ala Tyr Arg Asp Phe Asp Asp Thr Glu Pro Ser Trp Asp Asn Glu Asn 
                645                 650                 655     


Glu Ile Leu Thr Glu Leu Thr Cys Ile Ala Val Val Gly Ile Glu Asp 
            660                 665                 670         


Pro Val Arg Pro Glu Val Pro Asp Ala Ile Ala Lys Cys Lys Gln Ala 
        675                 680                 685             


Gly Ile Thr Val Arg Met Val Thr Gly Asp Asn Ile Asn Thr Ala Arg 
    690                 695                 700                 


Ala Ile Ala Thr Lys Cys Gly Ile Leu Thr Pro Gly Asp Asp Phe Leu 
705                 710                 715                 720 


Cys Leu Glu Gly Lys Glu Phe Asn Arg Leu Ile Arg Asn Glu Lys Gly 
                725                 730                 735     


Glu Val Glu Gln Glu Lys Leu Asp Lys Ile Trp Pro Lys Leu Arg Val 
            740                 745                 750         


Leu Ala Arg Ser Ser Pro Thr Asp Lys His Thr Leu Val Lys Gly Ile 
        755                 760                 765             


Ile Asp Ser Thr Val Gly Glu His Arg Gln Val Val Ala Val Thr Gly 
    770                 775                 780                 


Asp Gly Thr Asn Asp Gly Pro Ala Leu Lys Lys Ala Asp Val Gly Phe 
785                 790                 795                 800 


Ala Met Gly Ile Ala Gly Thr Asp Val Ala Lys Glu Ala Ser Asp Ile 
                805                 810                 815     


Ile Leu Thr Asp Asp Asn Phe Thr Ser Ile Val Lys Ala Val Met Trp 
            820                 825                 830         


Gly Arg Asn Val Tyr Asp Ser Ile Ser Lys Phe Leu Gln Phe Gln Leu 
        835                 840                 845             


Thr Val Asn Val Val Ala Val Ile Val Ala Phe Thr Gly Ala Cys Ile 
    850                 855                 860                 


Thr Gln Asp Ser Pro Leu Lys Ala Val Gln Met Leu Trp Val Asn Leu 
865                 870                 875                 880 


Ile Met Asp Thr Phe Ala Ser Leu Ala Leu Ala Thr Glu Pro Pro Thr 
                885                 890                 895     


Glu Ser Leu Leu Lys Arg Arg Pro Tyr Gly Arg Asn Lys Pro Leu Ile 
            900                 905                 910         


Ser Arg Thr Met Met Lys Asn Ile Leu Gly His Ala Phe Tyr Gln Leu 
        915                 920                 925             


Ile Val Ile Phe Ile Leu Val Phe Ala Gly Glu Lys Phe Phe Asp Ile 
    930                 935                 940                 


Asp Ser Gly Arg Lys Ala Pro Leu His Ser Pro Pro Ser Gln His Tyr 
945                 950                 955                 960 


Thr Ile Val Phe Asn Thr Phe Val Leu Met Gln Leu Phe Asn Glu Ile 
                965                 970                 975     


Asn Ser Arg Lys Ile His Gly Glu Lys Asn Val Phe Ser Gly Ile Tyr 
            980                 985                 990         


Arg Asn Ile Ile Phe Cys Ser Val  Val Leu Gly Thr Phe  Ile Cys Gln 
        995                 1000                 1005             


Ile Phe  Ile Val Glu Phe Gly  Gly Lys Pro Phe Ser  Cys Thr Ser 
    1010                 1015                 1020             


Leu Ser  Leu Ser Gln Trp Leu  Trp Cys Leu Phe Ile  Gly Ile Gly 
    1025                 1030                 1035             


Glu Leu  Leu Trp Gly Gln Phe  Ile Ser Ala Ile Pro  Thr Arg Ser 
    1040                 1045                 1050             


Leu Lys  Phe Leu Lys Glu Ala  Gly His Gly Thr Thr  Lys Glu Glu 
    1055                 1060                 1065             


Ile Thr  Lys Asp Ala Glu Gly  Leu Asp Glu Ile Asp  His Ala Glu 
    1070                 1075                 1080             


Met Glu  Leu Arg Arg Gly Gln  Ile Leu Trp Phe Arg  Gly Leu Asn 
    1085                 1090                 1095             


Arg Ile  Gln Thr Gln Ile Lys  Val Val Lys Ala Phe  His Ser Ser 
    1100                 1105                 1110             


Leu His  Glu Ser Ile Gln Lys  Pro Tyr Asn Gln Lys  Ser Ile His 
    1115                 1120                 1125             


Ser Phe  Met Thr His Pro Glu  Phe Ala Ile Glu Glu  Glu Leu Pro 
    1130                 1135                 1140             


Arg Thr  Pro Leu Leu Asp Glu  Glu Glu Glu Glu Asn  Pro Asp Lys 
    1145                 1150                 1155             


Ala Ser  Lys Phe Gly Thr Arg  Val Leu Leu Leu Asp  Gly Glu Val 
    1160                 1165                 1170             


Thr Pro  Tyr Ala Asn Thr Asn  Asn Asn Ala Val Asp  Cys Asn Gln 
    1175                 1180                 1185             


Val Gln  Leu Pro Gln Ser Asp  Ser Ser Leu Gln Ser  Leu Glu Thr 
    1190                 1195                 1200             


Ser Val  
    1205 


<210>  3172
<211>  294
<212>  PRT
<213>  homo sapiens

<400>  3172

Met Glu Arg Leu Thr Leu Thr Arg Thr Ile Gly Gly Pro Leu Leu Thr 
1               5                   10                  15      


Ala Thr Leu Leu Gly Lys Thr Thr Ile Asn Asp Tyr Gln Val Ile Arg 
            20                  25                  30          


Met Pro Phe Ser His Leu Ser Thr Tyr Ser Leu Val Trp Val Met Ala 
        35                  40                  45              


Ala Val Val Leu Cys Thr Ala Gln Val Gln Val Val Thr Gln Asp Glu 
    50                  55                  60                  


Arg Glu Gln Leu Tyr Thr Pro Ala Ser Leu Lys Cys Ser Leu Gln Asn 
65                  70                  75                  80  


Ala Gln Glu Ala Leu Ile Val Thr Trp Gln Lys Lys Lys Ala Val Ser 
                85                  90                  95      


Pro Glu Asn Met Val Thr Phe Ser Glu Asn His Gly Val Val Ile Gln 
            100                 105                 110         


Pro Ala Tyr Lys Asp Lys Ile Asn Ile Thr Gln Leu Gly Leu Gln Asn 
        115                 120                 125             


Ser Thr Ile Thr Phe Trp Asn Ile Thr Leu Glu Asp Glu Gly Cys Tyr 
    130                 135                 140                 


Met Cys Leu Phe Asn Thr Phe Gly Phe Gly Lys Ile Ser Gly Thr Ala 
145                 150                 155                 160 


Cys Leu Thr Val Tyr Val Gln Pro Ile Val Ser Leu His Tyr Lys Phe 
                165                 170                 175     


Ser Glu Asp His Leu Asn Ile Thr Cys Ser Ala Thr Ala Arg Pro Ala 
            180                 185                 190         


Pro Met Val Phe Trp Lys Val Pro Arg Ser Gly Ile Glu Asn Ser Thr 
        195                 200                 205             


Val Thr Leu Ser His Pro Asn Gly Thr Thr Ser Val Thr Ser Ile Leu 
    210                 215                 220                 


His Ile Lys Asp Pro Lys Asn Gln Val Gly Lys Glu Val Ile Cys Gln 
225                 230                 235                 240 


Val Leu His Leu Gly Thr Val Thr Asp Phe Lys Gln Thr Val Asn Lys 
                245                 250                 255     


Gly Tyr Trp Phe Ser Val Pro Leu Leu Leu Ser Ile Val Ser Leu Val 
            260                 265                 270         


Ile Leu Leu Val Leu Ile Ser Ile Leu Leu Tyr Trp Lys Arg His Arg 
        275                 280                 285             


Asn Gln Asp Arg Glu Pro 
    290                 


<210>  3173
<211>  625
<212>  PRT
<213>  homo sapiens

<400>  3173

Met Leu Asn Met Trp Lys Val Arg Glu Leu Val Asp Lys Ala Thr Asn 
1               5                   10                  15      


Val Val Met Asn Tyr Ser Glu Ile Glu Ser Lys Val Arg Glu Ala Thr 
            20                  25                  30          


Asn Asp Asp Pro Trp Gly Pro Ser Gly Gln Leu Met Gly Glu Ile Ala 
        35                  40                  45              


Lys Ala Thr Phe Met Tyr Glu Gln Phe Pro Glu Leu Met Asn Met Leu 
    50                  55                  60                  


Trp Ser Arg Met Leu Lys Asp Asn Lys Lys Asn Trp Arg Arg Val Tyr 
65                  70                  75                  80  


Lys Ser Leu Leu Leu Leu Ala Tyr Leu Ile Arg Asn Gly Ser Glu Arg 
                85                  90                  95      


Val Val Thr Ser Ala Arg Glu His Ile Tyr Asp Leu Arg Ser Leu Glu 
            100                 105                 110         


Asn Tyr His Phe Val Asp Glu His Gly Lys Asp Gln Gly Ile Asn Ile 
        115                 120                 125             


Arg Gln Lys Val Lys Glu Leu Val Glu Phe Ala Gln Asp Asp Asp Arg 
    130                 135                 140                 


Leu Arg Glu Glu Arg Lys Lys Ala Lys Lys Asn Lys Asp Lys Tyr Val 
145                 150                 155                 160 


Gly Val Ser Ser Asp Ser Val Gly Gly Phe Arg Tyr Ser Glu Arg Tyr 
                165                 170                 175     


Asp Pro Glu Pro Lys Ser Lys Trp Asp Glu Glu Trp Asp Lys Asn Lys 
            180                 185                 190         


Ser Ala Phe Pro Phe Ser Asp Lys Leu Gly Glu Leu Ser Asp Lys Ile 
        195                 200                 205             


Gly Ser Thr Ile Asp Asp Thr Ile Ser Lys Phe Arg Arg Lys Asp Arg 
    210                 215                 220                 


Glu Asp Ser Pro Glu Arg Cys Ser Asp Ser Asp Glu Glu Lys Lys Ala 
225                 230                 235                 240 


Arg Arg Gly Arg Ser Pro Lys Gly Glu Phe Lys Asp Glu Glu Glu Thr 
                245                 250                 255     


Val Thr Thr Lys His Ile His Ile Thr Gln Ala Thr Glu Thr Thr Thr 
            260                 265                 270         


Thr Arg His Lys Arg Thr Ala Asn Pro Ser Lys Thr Ile Asp Leu Gly 
        275                 280                 285             


Ala Ala Ala His Tyr Thr Gly Asp Lys Ala Ser Pro Asp Gln Asn Ala 
    290                 295                 300                 


Ser Thr His Thr Pro Gln Ser Ser Val Lys Thr Ser Val Pro Ser Ser 
305                 310                 315                 320 


Lys Ser Ser Gly Asp Leu Val Asp Leu Phe Asp Gly Thr Ser Gln Ser 
                325                 330                 335     


Thr Gly Gly Ser Ala Asp Leu Phe Gly Gly Phe Ala Asp Phe Gly Ser 
            340                 345                 350         


Ala Ala Ala Ser Gly Ser Phe Pro Ser Gln Val Thr Ala Thr Ser Gly 
        355                 360                 365             


Asn Gly Asp Phe Gly Asp Trp Ser Ala Phe Asn Gln Ala Pro Ser Gly 
    370                 375                 380                 


Pro Val Ala Ser Ser Gly Glu Phe Phe Gly Ser Ala Ser Gln Pro Ala 
385                 390                 395                 400 


Val Glu Leu Val Ser Gly Ser Gln Ser Ala Leu Gly Pro Pro Pro Ala 
                405                 410                 415     


Ala Ser Asn Ser Ser Asp Leu Phe Asp Leu Met Gly Ser Ser Gln Ala 
            420                 425                 430         


Thr Met Thr Ser Ser Gln Ser Met Asn Phe Ser Met Met Ser Thr Asn 
        435                 440                 445             


Thr Val Gly Leu Gly Leu Pro Met Ser Arg Ser Gln Asn Thr Asp Met 
    450                 455                 460                 


Val Gln Lys Ser Val Ser Lys Thr Leu Pro Ser Thr Trp Ser Asp Pro 
465                 470                 475                 480 


Ser Val Asn Ile Ser Leu Asp Asn Leu Leu Pro Gly Met Gln Pro Ser 
                485                 490                 495     


Lys Pro Gln Gln Pro Ser Leu Asn Thr Met Ile Gln Gln Gln Asn Met 
            500                 505                 510         


Gln Gln Pro Met Asn Val Met Thr Gln Ser Phe Gly Ala Val Asn Leu 
        515                 520                 525             


Ser Ser Pro Ser Asn Met Leu Pro Val Arg Pro Gln Thr Asn Ala Leu 
    530                 535                 540                 


Ile Gly Gly Pro Met Pro Met Ser Met Pro Asn Val Met Thr Gly Thr 
545                 550                 555                 560 


Met Gly Met Ala Pro Leu Gly Asn Thr Pro Met Met Asn Gln Ser Met 
                565                 570                 575     


Met Gly Met Asn Met Asn Ile Gly Met Ser Ala Ala Gly Met Gly Leu 
            580                 585                 590         


Thr Gly Thr Met Gly Met Gly Met Pro Asn Ile Ala Met Thr Ser Gly 
        595                 600                 605             


Thr Val Gln Pro Lys Gln Asp Ala Phe Ala Asn Phe Ala Asn Phe Ser 
    610                 615                 620                 


Lys 
625 


<210>  3174
<211>  435
<212>  PRT
<213>  homo sapiens

<400>  3174

Met Leu Pro Ala Arg Cys Ala Arg Leu Leu Thr Pro His Leu Leu Leu 
1               5                   10                  15      


Val Leu Val Gln Leu Ser Pro Ala Arg Gly His Arg Thr Thr Gly Pro 
            20                  25                  30          


Arg Phe Leu Ile Ser Asp Arg Asp Pro Gln Cys Asn Leu His Cys Ser 
        35                  40                  45              


Arg Thr Gln Pro Lys Pro Ile Cys Ala Ser Asp Gly Arg Ser Tyr Glu 
    50                  55                  60                  


Ser Met Cys Glu Tyr Gln Arg Ala Lys Cys Arg Asp Pro Thr Leu Gly 
65                  70                  75                  80  


Val Val His Arg Gly Arg Cys Lys Asp Ala Gly Gln Ser Lys Cys Arg 
                85                  90                  95      


Leu Glu Arg Ala Gln Ala Leu Glu Gln Ala Lys Lys Pro Gln Glu Ala 
            100                 105                 110         


Val Phe Val Pro Glu Cys Gly Glu Asp Gly Ser Phe Thr Gln Val Gln 
        115                 120                 125             


Cys His Thr Tyr Thr Gly Tyr Cys Trp Cys Val Thr Pro Asp Gly Lys 
    130                 135                 140                 


Pro Ile Ser Gly Ser Ser Val Gln Asn Lys Thr Pro Val Cys Ser Gly 
145                 150                 155                 160 


Ser Val Thr Asp Lys Pro Leu Ser Gln Gly Asn Ser Gly Arg Lys Asp 
                165                 170                 175     


Asp Gly Ser Lys Pro Thr Pro Thr Met Glu Thr Gln Pro Val Phe Asp 
            180                 185                 190         


Gly Asp Glu Ile Thr Ala Pro Thr Leu Trp Ile Lys His Leu Val Ile 
        195                 200                 205             


Lys Asp Ser Lys Leu Asn Asn Thr Asn Ile Arg Asn Ser Glu Lys Val 
    210                 215                 220                 


Tyr Ser Cys Asp Gln Glu Arg Gln Ser Ala Leu Glu Glu Ala Gln Gln 
225                 230                 235                 240 


Asn Pro Arg Glu Gly Ile Val Ile Pro Glu Cys Ala Pro Gly Gly Leu 
                245                 250                 255     


Tyr Lys Pro Val Gln Cys His Gln Ser Thr Gly Tyr Cys Trp Cys Val 
            260                 265                 270         


Leu Val Asp Thr Gly Arg Pro Leu Pro Gly Thr Ser Thr Arg Tyr Val 
        275                 280                 285             


Met Pro Ser Cys Glu Ser Asp Ala Arg Ala Lys Thr Thr Glu Ala Asp 
    290                 295                 300                 


Asp Pro Phe Lys Asp Arg Glu Leu Pro Gly Cys Pro Glu Gly Lys Lys 
305                 310                 315                 320 


Met Glu Phe Ile Thr Ser Leu Leu Asp Ala Leu Thr Thr Asp Met Val 
                325                 330                 335     


Gln Ala Ile Asn Ser Ala Ala Pro Thr Gly Gly Gly Arg Phe Ser Glu 
            340                 345                 350         


Pro Asp Pro Ser His Thr Leu Glu Glu Arg Val Val His Trp Tyr Phe 
        355                 360                 365             


Ser Gln Leu Asp Ser Asn Ser Ser Asn Asp Ile Asn Lys Arg Glu Met 
    370                 375                 380                 


Lys Pro Phe Lys Arg Tyr Val Lys Lys Lys Ala Lys Pro Lys Lys Cys 
385                 390                 395                 400 


Ala Arg Arg Phe Thr Asp Tyr Cys Asp Leu Asn Lys Asp Lys Val Ile 
                405                 410                 415     


Ser Leu Pro Glu Leu Lys Gly Cys Leu Gly Val Ser Lys Glu Val Gly 
            420                 425                 430         


Arg Leu Val 
        435 


<210>  3175
<211>  268
<212>  PRT
<213>  homo sapiens

<400>  3175

Met Pro Arg Ser Phe Leu Val Lys Lys His Phe Asn Ala Ser Lys Lys 
1               5                   10                  15      


Pro Asn Tyr Ser Glu Leu Asp Thr His Thr Val Ile Ile Ser Pro Tyr 
            20                  25                  30          


Leu Tyr Glu Ser Tyr Ser Met Pro Val Ile Pro Gln Pro Glu Ile Leu 
        35                  40                  45              


Ser Ser Gly Ala Tyr Ser Pro Ile Thr Val Trp Thr Thr Ala Ala Pro 
    50                  55                  60                  


Phe His Ala Gln Leu Pro Asn Gly Leu Ser Pro Leu Ser Gly Tyr Ser 
65                  70                  75                  80  


Ser Ser Leu Gly Arg Val Ser Pro Pro Pro Pro Ser Asp Thr Ser Ser 
                85                  90                  95      


Lys Asp His Ser Gly Ser Glu Ser Pro Ile Ser Asp Glu Glu Glu Arg 
            100                 105                 110         


Leu Gln Ser Lys Leu Ser Asp Pro His Ala Ile Glu Ala Glu Lys Phe 
        115                 120                 125             


Gln Cys Asn Leu Cys Asn Lys Thr Tyr Ser Thr Phe Ser Gly Leu Ala 
    130                 135                 140                 


Lys His Lys Gln Leu His Cys Asp Ala Gln Ser Arg Lys Ser Phe Ser 
145                 150                 155                 160 


Cys Lys Tyr Cys Asp Lys Glu Tyr Val Ser Leu Gly Ala Leu Lys Met 
                165                 170                 175     


His Ile Arg Thr His Thr Leu Pro Cys Val Cys Lys Ile Cys Gly Lys 
            180                 185                 190         


Ala Phe Ser Arg Pro Trp Leu Leu Gln Gly His Ile Arg Thr His Thr 
        195                 200                 205             


Gly Glu Lys Pro Phe Ser Cys Pro His Cys Asn Arg Ala Phe Ala Asp 
    210                 215                 220                 


Arg Ser Asn Leu Arg Ala His Leu Gln Thr His Ser Asp Val Lys Lys 
225                 230                 235                 240 


Tyr Gln Cys Lys Asn Cys Ser Lys Thr Phe Ser Arg Met Ser Leu Leu 
                245                 250                 255     


His Lys His Glu Glu Ser Gly Cys Cys Val Ala His 
            260                 265             


<210>  3176
<211>  258
<212>  PRT
<213>  homo sapiens

<400>  3176

Met Ser Ala Tyr Pro Lys Ser Tyr Asn Pro Phe Asp Asp Asp Gly Glu 
1               5                   10                  15      


Asp Glu Gly Ala Arg Pro Ala Pro Trp Arg Asp Ala Arg Asp Leu Pro 
            20                  25                  30          


Asp Gly Pro Asp Ala Pro Ala Asp Arg Gln Gln Tyr Leu Arg Gln Glu 
        35                  40                  45              


Val Leu Arg Arg Ala Glu Ala Thr Ala Ala Ser Thr Ser Arg Ser Leu 
    50                  55                  60                  


Ala Leu Met Tyr Glu Ser Glu Lys Val Gly Val Ala Ser Ser Glu Glu 
65                  70                  75                  80  


Leu Ala Arg Gln Arg Gly Val Leu Glu Arg Thr Glu Lys Met Val Asp 
                85                  90                  95      


Lys Met Asp Gln Asp Leu Lys Ile Ser Gln Lys His Ile Asn Ser Ile 
            100                 105                 110         


Lys Ser Val Phe Gly Gly Leu Val Asn Tyr Phe Lys Ser Lys Pro Val 
        115                 120                 125             


Glu Thr Pro Pro Glu Gln Asn Gly Thr Leu Thr Ser Gln Pro Asn Asn 
    130                 135                 140                 


Arg Leu Lys Glu Ala Ile Ser Thr Ser Lys Glu Gln Glu Ala Lys Tyr 
145                 150                 155                 160 


Gln Ala Ser His Pro Asn Leu Arg Lys Leu Asp Asp Thr Asp Pro Val 
                165                 170                 175     


Pro Arg Gly Ala Gly Ser Ala Met Ser Thr Asp Ala Tyr Pro Lys Asn 
            180                 185                 190         


Pro His Leu Arg Ala Tyr His Gln Lys Ile Asp Ser Asn Leu Asp Glu 
        195                 200                 205             


Leu Ser Met Gly Leu Gly Arg Leu Lys Asp Ile Ala Leu Gly Met Gln 
    210                 215                 220                 


Thr Glu Ile Glu Glu Gln Asp Asp Ile Leu Asp Arg Leu Thr Thr Lys 
225                 230                 235                 240 


Val Asp Lys Leu Asp Val Asn Ile Lys Ser Thr Glu Arg Lys Val Arg 
                245                 250                 255     


Gln Leu 
        


<210>  3177
<211>  357
<212>  PRT
<213>  homo sapiens

<400>  3177

Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Pro Gly Gln Thr Pro Glu Ala Ala Lys Thr His Ser Val Glu Thr Pro 
            20                  25                  30          


Tyr Gly Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg 
        35                  40                  45              


Pro Ala Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys 
    50                  55                  60                  


Phe Gln Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn 
65                  70                  75                  80  


Phe Val Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro 
                85                  90                  95      


Val Phe Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp 
            100                 105                 110         


Met Ile Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly 
        115                 120                 125             


Val Gly Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn 
    130                 135                 140                 


His Pro Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn 
145                 150                 155                 160 


Ala Lys Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr 
                165                 170                 175     


Ser Ser Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu 
            180                 185                 190         


Leu Ser Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr 
        195                 200                 205             


His Ala Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn 
    210                 215                 220                 


Asn Arg Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg 
225                 230                 235                 240 


Cys Pro Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala 
                245                 250                 255     


Val Val Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu 
            260                 265                 270         


Lys Met Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Gln Pro Gly Lys 
        275                 280                 285             


Leu Thr Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr Met Ala 
    290                 295                 300                 


Ser Ser Cys Met Thr Arg Leu Ser Arg Ser Arg Thr Ala Ser Leu Thr 
305                 310                 315                 320 


Ser Ala Ala Ser Val Asp Gly Asn Arg Ser Arg Ser Arg Thr Leu Ser 
                325                 330                 335     


Gln Ser Ser Glu Ser Gly Thr Leu Ser Ser Gly Pro Pro Gly His Thr 
            340                 345                 350         


Met Glu Val Ser Cys 
        355         


<210>  3178
<211>  1112
<212>  PRT
<213>  homo sapiens

<400>  3178

Met Arg Arg Asp Glu Arg Asp Ala Lys Ala Met Arg Ser Leu Gln Pro 
1               5                   10                  15      


Pro Asp Gly Ala Gly Ser Pro Pro Glu Ser Leu Arg Asn Gly Tyr Val 
            20                  25                  30          


Lys Ser Cys Val Ser Pro Leu Arg Gln Asp Pro Pro Arg Gly Phe Phe 
        35                  40                  45              


Phe His Leu Cys Arg Phe Cys Asn Val Glu Leu Arg Pro Pro Pro Ala 
    50                  55                  60                  


Ser Pro Gln Gln Pro Arg Arg Cys Ser Pro Phe Cys Arg Ala Arg Leu 
65                  70                  75                  80  


Ser Leu Gly Ala Leu Ala Ala Phe Val Leu Ala Leu Leu Leu Gly Ala 
                85                  90                  95      


Glu Pro Glu Ser Trp Ala Ala Gly Ala Ala Trp Leu Arg Thr Leu Leu 
            100                 105                 110         


Ser Val Cys Ser His Ser Leu Ser Pro Leu Phe Ser Ile Ala Cys Ala 
        115                 120                 125             


Phe Phe Phe Leu Thr Cys Phe Leu Thr Arg Thr Lys Arg Gly Pro Gly 
    130                 135                 140                 


Pro Gly Arg Ser Cys Gly Ser Trp Trp Leu Leu Ala Leu Pro Ala Cys 
145                 150                 155                 160 


Cys Tyr Leu Gly Asp Phe Leu Val Trp Gln Trp Trp Ser Trp Pro Trp 
                165                 170                 175     


Gly Asp Gly Asp Ala Gly Ser Ala Ala Pro His Thr Pro Pro Glu Ala 
            180                 185                 190         


Ala Ala Gly Arg Leu Leu Leu Val Leu Ser Cys Val Gly Leu Leu Leu 
        195                 200                 205             


Thr Leu Ala His Pro Leu Arg Leu Arg His Cys Val Leu Val Leu Leu 
    210                 215                 220                 


Leu Ala Ser Phe Val Trp Trp Val Ser Phe Thr Ser Leu Gly Ser Leu 
225                 230                 235                 240 


Pro Ser Ala Leu Arg Pro Leu Leu Ser Gly Leu Val Gly Gly Ala Gly 
                245                 250                 255     


Cys Leu Leu Ala Leu Gly Leu Asp His Phe Phe Gln Ile Arg Glu Ala 
            260                 265                 270         


Pro Leu His Pro Arg Leu Ser Ser Ala Ala Glu Glu Lys Val Pro Val 
        275                 280                 285             


Ile Arg Pro Arg Arg Arg Ser Ser Cys Val Ser Leu Gly Glu Thr Ala 
    290                 295                 300                 


Ala Ser Tyr Tyr Gly Ser Cys Lys Ile Phe Arg Arg Pro Ser Leu Pro 
305                 310                 315                 320 


Cys Ile Ser Arg Glu Gln Met Ile Leu Trp Asp Trp Asp Leu Lys Gln 
                325                 330                 335     


Trp Tyr Lys Pro His Tyr Gln Asn Ser Gly Gly Gly Asn Gly Val Asp 
            340                 345                 350         


Leu Ser Val Leu Asn Glu Ala Arg Asn Met Val Ser Asp Leu Leu Thr 
        355                 360                 365             


Asp Pro Ser Leu Pro Pro Gln Val Ile Ser Ser Leu Arg Ser Ile Ser 
    370                 375                 380                 


Ser Leu Met Gly Ala Phe Ser Gly Ser Cys Arg Pro Lys Ile Asn Pro 
385                 390                 395                 400 


Leu Thr Pro Phe Pro Gly Phe Tyr Pro Cys Ser Glu Ile Glu Asp Pro 
                405                 410                 415     


Ala Glu Lys Gly Asp Arg Lys Leu Asn Lys Gly Leu Asn Arg Asn Ser 
            420                 425                 430         


Leu Pro Thr Pro Gln Leu Arg Arg Ser Ser Gly Thr Ser Gly Leu Leu 
        435                 440                 445             


Pro Val Glu Gln Ser Ser Arg Trp Asp Arg Asn Asn Gly Lys Arg Pro 
    450                 455                 460                 


His Gln Glu Phe Gly Ile Ser Ser Gln Gly Cys Tyr Leu Asn Gly Pro 
465                 470                 475                 480 


Phe Asn Ser Asn Leu Leu Thr Ile Pro Lys Gln Arg Ser Ser Ser Val 
                485                 490                 495     


Ser Leu Thr His His Val Gly Leu Arg Arg Ala Gly Val Leu Ser Ser 
            500                 505                 510         


Leu Ser Pro Val Asn Ser Ser Asn His Gly Pro Val Ser Thr Gly Ser 
        515                 520                 525             


Leu Thr Asn Arg Ser Pro Ile Glu Phe Pro Asp Thr Ala Asp Phe Leu 
    530                 535                 540                 


Asn Lys Pro Ser Val Ile Leu Gln Arg Ser Leu Gly Asn Ala Pro Asn 
545                 550                 555                 560 


Thr Pro Asp Phe Tyr Gln Gln Leu Arg Asn Ser Asp Ser Asn Leu Cys 
                565                 570                 575     


Asn Ser Cys Gly His Gln Met Leu Lys Tyr Val Ser Thr Ser Glu Ser 
            580                 585                 590         


Asp Gly Thr Asp Cys Cys Ser Gly Lys Ser Gly Glu Glu Glu Asn Ile 
        595                 600                 605             


Phe Ser Lys Glu Ser Phe Lys Leu Met Glu Thr Gln Gln Glu Glu Glu 
    610                 615                 620                 


Thr Glu Lys Lys Asp Ser Arg Lys Leu Phe Gln Glu Gly Asp Lys Trp 
625                 630                 635                 640 


Leu Thr Glu Glu Ala Gln Ser Glu Gln Gln Thr Asn Ile Glu Gln Glu 
                645                 650                 655     


Val Ser Leu Asp Leu Ile Leu Val Glu Glu Tyr Asp Ser Leu Ile Glu 
            660                 665                 670         


Lys Met Ser Asn Trp Asn Phe Pro Ile Phe Glu Leu Val Glu Lys Met 
        675                 680                 685             


Gly Glu Lys Ser Gly Arg Ile Leu Ser Gln Val Met Tyr Thr Leu Phe 
    690                 695                 700                 


Gln Asp Thr Gly Leu Leu Glu Ile Phe Lys Ile Pro Thr Gln Gln Phe 
705                 710                 715                 720 


Met Asn Tyr Phe Arg Ala Leu Glu Asn Gly Tyr Arg Asp Ile Pro Tyr 
                725                 730                 735     


His Asn Arg Ile His Ala Thr Asp Val Leu His Ala Val Trp Tyr Leu 
            740                 745                 750         


Thr Thr Arg Pro Val Pro Gly Leu Gln Gln Ile His Asn Gly Cys Gly 
        755                 760                 765             


Thr Gly Asn Glu Thr Asp Ser Asp Gly Arg Ile Asn His Gly Arg Ile 
    770                 775                 780                 


Ala Tyr Ile Ser Ser Lys Ser Cys Ser Asn Pro Asp Glu Ser Tyr Gly 
785                 790                 795                 800 


Cys Leu Ser Ser Asn Ile Pro Ala Leu Glu Leu Met Ala Leu Tyr Val 
                805                 810                 815     


Ala Ala Ala Met His Asp Tyr Asp His Pro Gly Arg Thr Asn Ala Phe 
            820                 825                 830         


Leu Val Ala Thr Asn Ala Pro Gln Ala Val Leu Tyr Asn Asp Arg Ser 
        835                 840                 845             


Val Leu Glu Asn His His Ala Ala Ser Ala Trp Asn Leu Tyr Leu Ser 
    850                 855                 860                 


Arg Pro Glu Tyr Asn Phe Leu Leu His Leu Asp His Val Glu Phe Lys 
865                 870                 875                 880 


Arg Phe Arg Phe Leu Val Ile Glu Ala Ile Leu Ala Thr Asp Leu Lys 
                885                 890                 895     


Lys His Phe Asp Phe Leu Ala Glu Phe Asn Ala Lys Ala Asn Asp Val 
            900                 905                 910         


Asn Ser Asn Gly Ile Glu Trp Ser Asn Glu Asn Asp Arg Leu Leu Val 
        915                 920                 925             


Cys Gln Val Cys Ile Lys Leu Ala Asp Ile Asn Gly Pro Ala Lys Val 
    930                 935                 940                 


Arg Asp Leu His Leu Lys Trp Thr Glu Gly Ile Val Asn Glu Phe Tyr 
945                 950                 955                 960 


Glu Gln Gly Asp Glu Glu Ala Asn Leu Gly Leu Pro Ile Ser Pro Phe 
                965                 970                 975     


Met Asp Arg Ser Ser Pro Gln Leu Ala Lys Leu Gln Glu Ser Phe Ile 
            980                 985                 990         


Thr His Ile Val Gly Pro Leu Cys  Asn Ser Tyr Asp Ala  Ala Gly Leu 
        995                 1000                 1005             


Leu Pro  Gly Gln Trp Leu Glu  Ala Glu Glu Asp Asn  Asp Thr Glu 
    1010                 1015                 1020             


Ser Gly  Asp Asp Glu Asp Gly  Glu Glu Leu Asp Thr  Glu Asp Glu 
    1025                 1030                 1035             


Glu Met  Glu Asn Asn Leu Asn  Pro Lys Pro Pro Arg  Arg Lys Ser 
    1040                 1045                 1050             


Arg Arg  Arg Ile Phe Cys Gln  Leu Met His His Leu  Thr Glu Asn 
    1055                 1060                 1065             


His Lys  Ile Trp Lys Glu Ile  Val Glu Glu Glu Glu  Lys Cys Lys 
    1070                 1075                 1080             


Ala Asp  Gly Asn Lys Leu Gln  Val Glu Asn Ser Ser  Leu Pro Gln 
    1085                 1090                 1095             


Ala Asp  Glu Ile Gln Val Ile  Glu Glu Ala Asp Glu  Glu Glu 
    1100                 1105                 1110         


<210>  3179
<211>  709
<212>  PRT
<213>  homo sapiens

<400>  3179

Met Ser Phe Pro Lys Ala Pro Leu Lys Arg Phe Asn Asp Pro Ser Gly 
1               5                   10                  15      


Cys Ala Pro Ser Pro Gly Ala Tyr Asp Val Lys Thr Leu Glu Val Leu 
            20                  25                  30          


Lys Gly Pro Val Ser Phe Gln Lys Ser Gln Arg Phe Lys Gln Gln Lys 
        35                  40                  45              


Glu Ser Lys Gln Asn Leu Asn Val Asp Lys Asp Thr Thr Leu Pro Ala 
    50                  55                  60                  


Ser Ala Arg Lys Val Lys Ser Ser Glu Ser Lys Ile Arg Val Leu Leu 
65                  70                  75                  80  


Gln Glu Arg Gly Ala Gln Asp Arg Arg Ile Gln Asp Leu Glu Thr Glu 
                85                  90                  95      


Leu Glu Lys Met Glu Ala Arg Leu Asn Ala Ala Leu Arg Glu Lys Thr 
            100                 105                 110         


Ser Leu Ser Ala Asn Asn Ala Thr Leu Glu Lys Gln Leu Ile Glu Leu 
        115                 120                 125             


Thr Arg Thr Asn Glu Leu Leu Lys Ser Lys Phe Ser Glu Asn Gly Asn 
    130                 135                 140                 


Gln Lys Asn Leu Arg Ile Leu Ser Leu Glu Leu Met Lys Leu Arg Asn 
145                 150                 155                 160 


Lys Arg Glu Thr Lys Met Arg Gly Met Met Ala Lys Gln Glu Gly Met 
                165                 170                 175     


Glu Met Lys Leu Gln Val Thr Gln Arg Ser Leu Glu Glu Ser Gln Gly 
            180                 185                 190         


Lys Ile Ala Gln Leu Glu Gly Lys Leu Val Ser Ile Glu Lys Glu Lys 
        195                 200                 205             


Ile Asp Glu Lys Ser Glu Thr Glu Lys Leu Leu Glu Tyr Ile Glu Glu 
    210                 215                 220                 


Ile Ser Cys Ala Ser Asp Gln Val Glu Lys Tyr Lys Leu Asp Ile Ala 
225                 230                 235                 240 


Gln Leu Glu Glu Asn Leu Lys Glu Lys Asn Asp Glu Ile Leu Ser Leu 
                245                 250                 255     


Lys Gln Ser Leu Glu Glu Asn Ile Val Ile Leu Ser Lys Gln Val Glu 
            260                 265                 270         


Asp Leu Asn Val Lys Cys Gln Leu Leu Glu Lys Glu Lys Glu Asp His 
        275                 280                 285             


Val Asn Arg Asn Arg Glu His Asn Glu Asn Leu Asn Ala Glu Met Gln 
    290                 295                 300                 


Asn Leu Lys Gln Lys Phe Ile Leu Glu Gln Gln Glu Arg Glu Lys Leu 
305                 310                 315                 320 


Gln Gln Lys Glu Leu Gln Ile Asp Ser Leu Leu Gln Gln Glu Lys Glu 
                325                 330                 335     


Leu Ser Ser Ser Leu His Gln Lys Leu Cys Ser Phe Gln Glu Glu Met 
            340                 345                 350         


Val Lys Glu Lys Asn Leu Phe Glu Glu Glu Leu Lys Gln Thr Leu Asp 
        355                 360                 365             


Glu Leu Asp Lys Leu Gln Gln Lys Glu Glu Gln Ala Glu Arg Leu Val 
    370                 375                 380                 


Lys Gln Leu Glu Glu Glu Ala Lys Ser Arg Ala Glu Glu Leu Lys Leu 
385                 390                 395                 400 


Leu Glu Glu Lys Leu Lys Gly Lys Glu Ala Glu Leu Glu Lys Ser Ser 
                405                 410                 415     


Ala Ala His Thr Gln Ala Thr Leu Leu Leu Gln Glu Lys Tyr Asp Ser 
            420                 425                 430         


Met Val Gln Ser Leu Glu Asp Val Thr Ala Gln Phe Glu Ser Tyr Lys 
        435                 440                 445             


Ala Leu Thr Ala Ser Glu Ile Glu Asp Leu Lys Leu Glu Asn Ser Ser 
    450                 455                 460                 


Leu Gln Glu Lys Ala Ala Lys Ala Gly Lys Asn Ala Glu Asp Val Gln 
465                 470                 475                 480 


His Gln Ile Leu Ala Thr Glu Ser Ser Asn Gln Glu Tyr Val Arg Met 
                485                 490                 495     


Leu Leu Asp Leu Gln Thr Lys Ser Ala Leu Lys Glu Thr Glu Ile Lys 
            500                 505                 510         


Glu Ile Thr Val Ser Phe Leu Gln Lys Ile Thr Asp Leu Gln Asn Gln 
        515                 520                 525             


Leu Lys Gln Gln Glu Glu Asp Phe Arg Lys Gln Leu Glu Asp Glu Glu 
    530                 535                 540                 


Gly Arg Lys Ala Glu Lys Glu Asn Thr Thr Ala Glu Leu Thr Glu Glu 
545                 550                 555                 560 


Ile Asn Lys Trp Arg Leu Leu Tyr Glu Glu Leu Tyr Asn Lys Thr Lys 
                565                 570                 575     


Pro Phe Gln Leu Gln Leu Asp Ala Phe Glu Val Glu Lys Gln Ala Leu 
            580                 585                 590         


Leu Asn Glu His Gly Ala Ala Gln Glu Gln Leu Asn Lys Ile Arg Asp 
        595                 600                 605             


Ser Tyr Ala Lys Leu Leu Gly His Gln Asn Leu Lys Gln Lys Ile Lys 
    610                 615                 620                 


His Val Val Lys Leu Lys Asp Glu Asn Ser Gln Leu Lys Ser Glu Val 
625                 630                 635                 640 


Ser Lys Leu Arg Cys Gln Leu Ala Lys Lys Lys Gln Ser Glu Thr Lys 
                645                 650                 655     


Leu Gln Glu Glu Leu Asn Lys Val Leu Gly Ile Lys His Phe Asp Pro 
            660                 665                 670         


Ser Lys Ala Phe His His Glu Ser Lys Glu Asn Phe Ala Leu Lys Thr 
        675                 680                 685             


Pro Leu Lys Glu Gly Asn Thr Asn Cys Tyr Arg Ala Pro Met Glu Cys 
    690                 695                 700                 


Gln Glu Ser Trp Lys 
705                 


<210>  3180
<211>  171
<212>  PRT
<213>  homo sapiens

<400>  3180

Met Val Lys Leu Asn Ser Asn Pro Ser Glu Lys Gly Thr Lys Pro Pro 
1               5                   10                  15      


Ser Val Glu Asp Gly Phe Gln Thr Val Pro Leu Ile Thr Pro Leu Glu 
            20                  25                  30          


Val Asn His Leu Gln Leu Pro Ala Pro Glu Lys Val Ile Val Lys Thr 
        35                  40                  45              


Arg Thr Glu Tyr Gln Pro Glu Gln Lys Asn Lys Gly Lys Phe Arg Val 
    50                  55                  60                  


Pro Lys Ile Ala Glu Phe Thr Val Thr Ile Leu Val Ser Leu Ala Leu 
65                  70                  75                  80  


Ala Phe Leu Ala Cys Ile Val Phe Leu Val Val Tyr Lys Ala Phe Thr 
                85                  90                  95      


Tyr Asp His Ser Cys Pro Glu Gly Phe Val Tyr Lys His Lys Arg Cys 
            100                 105                 110         


Ile Pro Ala Ser Leu Asp Ala Tyr Tyr Ser Ser Gln Asp Pro Asn Ser 
        115                 120                 125             


Arg Ser Arg Phe Tyr Thr Val Ile Ser His Tyr Ser Val Ala Lys Gln 
    130                 135                 140                 


Ser Thr Ala Arg Ala Ile Gly Pro Trp Leu Ser Ala Ala Ala Val Ile 
145                 150                 155                 160 


His Glu Pro Lys Pro Pro Lys Thr Gln Gly His 
                165                 170     


<210>  3181
<211>  638
<212>  PRT
<213>  homo sapiens

<400>  3181

Met Leu Leu Ala Gln Ile Asn Arg Asp Ser Gln Gly Met Thr Glu Phe 
1               5                   10                  15      


Pro Gly Gly Gly Met Glu Ala Gln His Val Thr Leu Cys Leu Thr Glu 
            20                  25                  30          


Ala Val Thr Val Ala Asp Gly Asp Asn Leu Glu Asn Met Glu Gly Val 
        35                  40                  45              


Ser Leu Gln Ala Val Thr Leu Ala Asp Gly Ser Thr Ala Tyr Ile Gln 
    50                  55                  60                  


His Asn Ser Lys Asp Ala Lys Leu Ile Asp Gly Gln Val Ile Gln Leu 
65                  70                  75                  80  


Glu Asp Gly Ser Ala Ala Tyr Val Gln His Val Pro Ile Pro Lys Ser 
                85                  90                  95      


Thr Gly Asp Ser Leu Arg Leu Glu Asp Gly Gln Ala Val Gln Leu Glu 
            100                 105                 110         


Asp Gly Thr Thr Ala Phe Ile His His Thr Ser Lys Asp Ser Tyr Asp 
        115                 120                 125             


Gln Ser Ala Leu Gln Ala Val Gln Leu Glu Asp Gly Thr Thr Ala Tyr 
    130                 135                 140                 


Ile His His Ala Val Gln Val Pro Gln Ser Asp Thr Ile Leu Ala Ile 
145                 150                 155                 160 


Gln Ala Asp Gly Thr Val Ala Gly Leu His Thr Gly Asp Ala Thr Ile 
                165                 170                 175     


Asp Pro Asp Thr Ile Ser Ala Leu Glu Gln Tyr Ala Ala Lys Val Ser 
            180                 185                 190         


Ile Asp Gly Ser Glu Ser Val Ala Gly Thr Gly Met Ile Gly Glu Asn 
        195                 200                 205             


Glu Gln Glu Lys Lys Met Gln Ile Val Leu Gln Gly His Ala Thr Arg 
    210                 215                 220                 


Val Thr Ala Lys Ser Gln Gln Ser Gly Glu Lys Ala Phe Arg Cys Glu 
225                 230                 235                 240 


Tyr Asp Gly Cys Gly Lys Leu Tyr Thr Thr Ala His His Leu Lys Val 
                245                 250                 255     


His Glu Arg Ser His Thr Gly Asp Arg Pro Tyr Gln Cys Glu His Ala 
            260                 265                 270         


Gly Cys Gly Lys Ala Phe Ala Thr Gly Tyr Gly Leu Lys Ser His Val 
        275                 280                 285             


Arg Thr His Thr Gly Glu Lys Pro Tyr Arg Cys Ser Glu Asp Asn Cys 
    290                 295                 300                 


Thr Lys Ser Phe Lys Thr Ser Gly Asp Leu Gln Lys His Ile Arg Thr 
305                 310                 315                 320 


His Thr Gly Glu Arg Pro Phe Lys Cys Pro Phe Glu Gly Cys Gly Arg 
                325                 330                 335     


Ser Phe Thr Thr Ser Asn Ile Arg Lys Val His Val Arg Thr His Thr 
            340                 345                 350         


Gly Glu Arg Pro Tyr Tyr Cys Thr Glu Pro Gly Cys Gly Arg Ala Phe 
        355                 360                 365             


Ala Ser Ala Thr Asn Tyr Lys Asn His Val Arg Ile His Thr Gly Glu 
    370                 375                 380                 


Lys Pro Tyr Val Cys Thr Val Pro Gly Cys Asp Lys Arg Phe Thr Glu 
385                 390                 395                 400 


Tyr Ser Ser Leu Tyr Lys His His Val Val His Thr His Ser Lys Pro 
                405                 410                 415     


Tyr Asn Cys Asn His Cys Gly Lys Thr Tyr Lys Gln Ile Ser Thr Leu 
            420                 425                 430         


Ala Met His Lys Arg Thr Ala His Asn Asp Thr Glu Pro Ile Glu Glu 
        435                 440                 445             


Glu Gln Glu Ala Phe Phe Glu Pro Pro Pro Gly Gln Gly Glu Asp Val 
    450                 455                 460                 


Leu Lys Gly Ser Gln Ile Thr Tyr Val Thr Gly Val Glu Gly Asp Asp 
465                 470                 475                 480 


Val Val Ser Thr Gln Val Ala Thr Val Thr Gln Ser Gly Leu Ser Gln 
                485                 490                 495     


Gln Val Thr Leu Ile Ser Gln Asp Gly Thr Gln His Val Asn Ile Ser 
            500                 505                 510         


Gln Ala Asp Met Gln Ala Ile Gly Asn Thr Ile Thr Met Val Thr Gln 
        515                 520                 525             


Asp Gly Thr Pro Ile Thr Val Pro Ala His Asp Ala Val Ile Ser Ser 
    530                 535                 540                 


Ala Gly Thr His Ser Val Ala Met Val Thr Ala Glu Gly Thr Glu Gly 
545                 550                 555                 560 


Glu Gln Val Ala Ile Val Ala Gln Asp Leu Ala Ala Phe His Thr Ala 
                565                 570                 575     


Ser Ser Glu Met Gly His Gln Gln His Ser His His Leu Val Thr Thr 
            580                 585                 590         


Glu Thr Arg Pro Leu Thr Leu Val Ala Thr Ser Asn Gly Thr Gln Ile 
        595                 600                 605             


Ala Val Gln Leu Gly Glu Gln Pro Ser Leu Glu Glu Ala Ile Arg Ile 
    610                 615                 620                 


Ala Ser Arg Ile Gln Gln Gly Glu Thr Pro Gly Leu Asp Asp 
625                 630                 635             


<210>  3182
<211>  1393
<212>  PRT
<213>  homo sapiens

<400>  3182

Met Ala Cys Ser Ile Val Gln Phe Cys Tyr Phe Gln Asp Leu Gln Ala 
1               5                   10                  15      


Ala Arg Asp Phe Leu Phe Pro His Leu Arg Glu Glu Ile Leu Ser Gly 
            20                  25                  30          


Ala Leu Arg Arg Asp Pro Ser Lys Ser Thr Asp Trp Glu Asp Asp Gly 
        35                  40                  45              


Trp Gly Ala Trp Glu Glu Asn Glu Pro Gln Glu Pro Glu Glu Glu Gly 
    50                  55                  60                  


Asn Thr Cys Lys Thr Gln Lys Thr Ser Trp Leu Gln Asp Cys Val Leu 
65                  70                  75                  80  


Ser Leu Ser Pro Thr Asn Asp Leu Met Val Ile Ala Arg Glu Gln Lys 
                85                  90                  95      


Ala Val Phe Leu Val Pro Lys Trp Lys Tyr Ser Asp Lys Gly Lys Glu 
            100                 105                 110         


Glu Met Gln Phe Ala Val Gly Trp Ser Gly Ser Leu Asn Val Glu Glu 
        115                 120                 125             


Gly Glu Cys Val Thr Ser Ala Leu Cys Ile Pro Leu Ala Ser Gln Lys 
    130                 135                 140                 


Arg Ser Ser Thr Gly Arg Pro Asp Trp Thr Cys Ile Val Val Gly Phe 
145                 150                 155                 160 


Thr Ser Gly Tyr Val Arg Phe Tyr Thr Glu Asn Gly Val Leu Leu Leu 
                165                 170                 175     


Ala Gln Leu Leu Asn Glu Asp Pro Val Leu Gln Leu Lys Cys Arg Thr 
            180                 185                 190         


Tyr Glu Ile Pro Arg His Pro Gly Val Thr Glu Gln Asn Glu Glu Leu 
        195                 200                 205             


Ser Ile Leu Tyr Pro Ala Ala Ile Val Thr Ile Asp Gly Phe Ser Leu 
    210                 215                 220                 


Phe Gln Ser Leu Arg Ala Cys Arg Asn Gln Val Ala Lys Ala Ala Ala 
225                 230                 235                 240 


Ser Gly Asn Glu Asn Ile Gln Pro Pro Pro Leu Ala Tyr Lys Lys Trp 
                245                 250                 255     


Gly Leu Gln Asp Ile Asp Thr Ile Ile Asp His Ala Ser Val Gly Ile 
            260                 265                 270         


Met Thr Leu Ser Pro Phe Asp Gln Met Lys Thr Ala Ser Asn Ile Gly 
        275                 280                 285             


Gly Phe Asn Ala Ala Ile Lys Asn Ser Pro Pro Ala Met Ser Gln Tyr 
    290                 295                 300                 


Ile Thr Val Gly Ser Asn Pro Phe Thr Gly Phe Phe Tyr Ala Leu Glu 
305                 310                 315                 320 


Gly Ser Thr Gln Pro Leu Leu Ser His Val Ala Leu Ala Val Ala Ser 
                325                 330                 335     


Lys Leu Thr Ser Ala Leu Phe Asn Ala Ala Ser Gly Trp Leu Gly Trp 
            340                 345                 350         


Lys Ser Lys His Glu Glu Glu Ala Val Gln Lys Gln Lys Pro Lys Val 
        355                 360                 365             


Glu Pro Ala Thr Pro Leu Ala Val Arg Phe Gly Leu Pro Asp Ser Arg 
    370                 375                 380                 


Arg His Gly Glu Ser Ile Cys Leu Ser Pro Cys Asn Thr Leu Ala Ala 
385                 390                 395                 400 


Val Thr Asp Asp Phe Gly Arg Val Ile Leu Leu Asp Val Ala Arg Gly 
                405                 410                 415     


Ile Ala Ile Arg Met Trp Lys Gly Tyr Arg Asp Ala Gln Ile Gly Trp 
            420                 425                 430         


Ile Gln Thr Val Glu Asp Leu His Glu Arg Val Pro Glu Lys Ala Asp 
        435                 440                 445             


Phe Ser Pro Phe Gly Asn Ser Gln Gly Pro Ser Arg Val Ala Gln Phe 
    450                 455                 460                 


Leu Val Ile Tyr Ala Pro Arg Arg Gly Ile Leu Glu Val Trp Ser Thr 
465                 470                 475                 480 


Gln Gln Gly Pro Arg Val Gly Ala Phe Asn Val Gly Lys His Cys Arg 
                485                 490                 495     


Leu Leu Tyr Pro Gly Tyr Lys Ile Met Gly Leu Asn Asn Val Thr Ser 
            500                 505                 510         


Gln Ser Trp Gln Pro Gln Thr Tyr Gln Ile Cys Leu Val Asp Pro Val 
        515                 520                 525             


Ser Gly Ser Val Lys Thr Val Asn Val Pro Phe His Leu Ala Leu Ser 
    530                 535                 540                 


Asp Lys Lys Ser Glu Arg Ala Lys Asp Met His Leu Val Lys Lys Leu 
545                 550                 555                 560 


Ala Ala Leu Leu Lys Thr Lys Ser Pro Asn Leu Asp Leu Val Glu Thr 
                565                 570                 575     


Glu Ile Lys Glu Leu Ile Leu Asp Ile Lys Tyr Pro Ala Thr Lys Lys 
            580                 585                 590         


Gln Ala Leu Glu Ser Ile Leu Ala Ser Glu Arg Leu Pro Phe Ser Cys 
        595                 600                 605             


Leu Arg Asn Ile Thr Gln Thr Leu Met Asp Thr Leu Lys Ser Gln Glu 
    610                 615                 620                 


Leu Glu Ser Val Asp Glu Gly Leu Leu Gln Phe Cys Ala Asn Lys Leu 
625                 630                 635                 640 


Lys Leu Leu Gln Leu Tyr Glu Ser Val Ser Gln Leu Asn Ser Leu Asp 
                645                 650                 655     


Phe His Leu Asp Thr Pro Phe Ser Asp Asn Asp Leu Ala Leu Leu Leu 
            660                 665                 670         


Arg Leu Asp Glu Lys Glu Leu Leu Lys Leu Gln Ala Leu Leu Glu Lys 
        675                 680                 685             


Tyr Lys Gln Glu Asn Thr Arg Thr Asn Val Arg Phe Ser Asp Asp Lys 
    690                 695                 700                 


Asp Gly Val Leu Pro Val Lys Thr Phe Leu Glu Tyr Leu Glu Tyr Glu 
705                 710                 715                 720 


Lys Asp Val Leu Asn Ile Lys Lys Ile Ser Glu Glu Glu Tyr Val Ala 
                725                 730                 735     


Leu Gly Ser Phe Phe Phe Trp Lys Cys Leu His Gly Glu Ser Ser Thr 
            740                 745                 750         


Glu Asp Met Cys His Thr Leu Glu Ser Ala Gly Leu Ser Pro Gln Leu 
        755                 760                 765             


Leu Leu Ser Leu Leu Leu Ser Val Trp Leu Ser Lys Glu Lys Asp Ile 
    770                 775                 780                 


Leu Asp Lys Pro Gln Ser Ile Cys Cys Leu His Thr Met Leu Ser Leu 
785                 790                 795                 800 


Leu Ser Lys Met Lys Val Ala Ile Asp Glu Thr Trp Asp Ser Gln Ser 
                805                 810                 815     


Val Ser Pro Trp Trp Gln Gln Met Arg Thr Ala Cys Ile Gln Ser Glu 
            820                 825                 830         


Asn Asn Gly Ala Ala Leu Leu Ser Ala His Val Gly His Ser Val Ala 
        835                 840                 845             


Ala Gln Ile Ser Asn Asn Met Thr Glu Lys Lys Phe Ser Gln Thr Val 
    850                 855                 860                 


Leu Gly Ala Asp Ser Glu Ala Leu Thr Asp Ser Trp Glu Ala Leu Ser 
865                 870                 875                 880 


Leu Asp Thr Glu Tyr Trp Lys Leu Leu Leu Lys Gln Leu Glu Asp Cys 
                885                 890                 895     


Leu Ile Leu Gln Thr Leu Leu His Ser Lys Gly Asn Thr Gln Thr Ser 
            900                 905                 910         


Lys Val Ser Ser Leu Gln Ala Glu Pro Leu Pro Arg Leu Ser Val Lys 
        915                 920                 925             


Lys Leu Leu Glu Gly Gly Lys Gly Gly Ile Ala Asp Ser Val Ala Lys 
    930                 935                 940                 


Trp Ile Phe Lys Gln Asp Phe Ser Pro Glu Val Leu Lys Leu Ala Asn 
945                 950                 955                 960 


Glu Glu Arg Asp Ala Glu Asn Pro Asp Glu Pro Lys Glu Gly Val Asn 
                965                 970                 975     


Arg Ser Phe Leu Glu Val Ser Glu Met Glu Met Asp Leu Gly Ala Ile 
            980                 985                 990         


Pro Asp Leu Leu His Leu Ala Tyr  Glu Gln Phe Pro Cys  Ser Leu Glu 
        995                 1000                 1005             


Leu Asp  Val Leu His Ala His  Cys Cys Trp Glu Tyr  Val Val Gln 
    1010                 1015                 1020             


Trp Asn  Lys Asp Pro Glu Glu  Ala Arg Phe Phe Val  Arg Ser Ile 
    1025                 1030                 1035             


Glu His  Leu Lys Gln Ile Phe  Asn Ala His Val Gln  Asn Gly Ile 
    1040                 1045                 1050             


Ala Leu  Met Met Trp Asn Thr  Phe Leu Val Lys Arg  Phe Ser Ala 
    1055                 1060                 1065             


Ala Thr  Tyr Leu Met Asp Lys  Val Gly Lys Ser Pro  Lys Asp Arg 
    1070                 1075                 1080             


Leu Cys  Arg Arg Asp Val Gly  Met Ser Asp Thr Ala  Met Thr Ser 
    1085                 1090                 1095             


Phe Leu  Gly Ser Cys Leu Asp  Leu Leu Gln Ile Leu  Met Glu Ala 
    1100                 1105                 1110             


Asp Val  Ser Arg Asp Glu Ile  Gln Val Pro Val Leu  Asp Thr Glu 
    1115                 1120                 1125             


Asp Ala  Trp Leu Ser Val Glu  Gly Pro Ile Ser Ile  Val Glu Leu 
    1130                 1135                 1140             


Ala Leu  Glu Gln Lys His Ile  His Tyr Pro Leu Val  Glu His His 
    1145                 1150                 1155             


Ser Ile  Leu Cys Ser Ile Leu  Tyr Ala Val Met Arg  Phe Ser Leu 
    1160                 1165                 1170             


Lys Thr  Val Lys Pro Leu Ser  Leu Phe Asp Ser Lys  Gly Lys Asn 
    1175                 1180                 1185             


Ala Phe  Phe Lys Asp Leu Thr  Ser Ile Gln Leu Leu  Pro Ser Gly 
    1190                 1195                 1200             


Glu Met  Asp Pro Asn Phe Ile  Ser Val Arg Gln Gln  Phe Leu Leu 
    1205                 1210                 1215             


Lys Val  Val Ser Ala Ala Val  Gln Ala Gln His Ser  Ala Thr Lys 
    1220                 1225                 1230             


Val Lys  Asp Pro Thr Glu Glu  Ala Thr Pro Thr Pro  Phe Gly Lys 
    1235                 1240                 1245             


Asp Gln  Asp Trp Pro Ala Leu  Ala Val Asp Leu Ala  His His Leu 
    1250                 1255                 1260             


Gln Val  Ser Glu Asp Val Val  Arg Arg His Tyr Val  Gly Glu Leu 
    1265                 1270                 1275             


Tyr Asn  Tyr Gly Val Asp His  Leu Gly Glu Glu Ala  Ile Leu Gln 
    1280                 1285                 1290             


Val His  Asp Lys Glu Val Leu  Ala Ser Gln Leu Leu  Val Leu Thr 
    1295                 1300                 1305             


Gly Gln  Arg Leu Ala His Ala  Leu Leu His Thr Gln  Thr Lys Glu 
    1310                 1315                 1320             


Gly Met  Glu Leu Leu Ala Arg  Leu Pro Pro Thr Leu  Cys Thr Trp 
    1325                 1330                 1335             


Leu Lys  Ala Met Asp Pro Gln  Asp Leu Gln Asn Thr  Glu Val Pro 
    1340                 1345                 1350             


Ile Ala  Thr Thr Ala Lys Leu  Val Asn Lys Val Ile  Glu Leu Leu 
    1355                 1360                 1365             


Pro Glu  Lys His Gly Gln Tyr  Gly Leu Ala Leu His  Leu Ile Glu 
    1370                 1375                 1380             


Ala Val  Glu Ala Ile Ser Leu  Pro Ser Leu 
    1385                 1390             


<210>  3183
<211>  129
<212>  PRT
<213>  homo sapiens

<400>  3183

Met Thr Met Thr Thr Met Pro Glu Ser Leu Asn Ser Pro Val Ser Gly 
1               5                   10                  15      


Lys Ala Val Phe Met Glu Phe Gly Pro Pro Asn Gln Gln Met Ser Pro 
            20                  25                  30          


Ser Pro Met Ser His Gly His Tyr Ser Met His Cys Leu His Ser Ala 
        35                  40                  45              


Gly His Ser Gln Pro Asp Gly Ala Tyr Ser Ser Ala Ser Ser Phe Ser 
    50                  55                  60                  


Arg Pro Leu Gly Tyr Pro Tyr Val Asn Ser Val Ser Ser His Ala Ser 
65                  70                  75                  80  


Ser Pro Tyr Ile Ser Ser Val Gln Ser Tyr Pro Gly Ser Ala Ser Leu 
                85                  90                  95      


Ala Gln Ser Arg Leu Glu Asp Pro Gly Gln Asp Leu Val Pro Lys Gln 
            100                 105                 110         


Ala Ile Gln Val Gln Glu Ala Asp Glu Ala Gly Trp Gly Gly Ser Gly 
        115                 120                 125             


Gly 
    


<210>  3184
<211>  122
<212>  PRT
<213>  homo sapiens

<400>  3184

Met Ser Thr Pro Ala Arg Arg Arg Leu Met Arg Asp Phe Lys Arg Leu 
1               5                   10                  15      


Gln Glu Asp Pro Pro Ala Gly Val Ser Gly Ala Pro Ser Glu Asn Asn 
            20                  25                  30          


Ile Met Val Trp Asn Ala Val Ile Phe Gly Pro Glu Gly Thr Pro Phe 
        35                  40                  45              


Glu Asp Val Tyr Ala Asp Gly Ser Ile Cys Leu Asp Ile Leu Gln Asn 
    50                  55                  60                  


Arg Trp Ser Pro Thr Tyr Asp Val Ser Ser Ile Leu Thr Ser Ile Gln 
65                  70                  75                  80  


Ser Leu Leu Asp Glu Pro Asn Pro Asn Ser Pro Ala Asn Ser Gln Ala 
                85                  90                  95      


Ala Gln Leu Tyr Gln Glu Asn Lys Arg Glu Tyr Glu Lys Arg Val Ser 
            100                 105                 110         


Ala Ile Val Glu Gln Ser Trp Arg Asp Cys 
        115                 120         


<210>  3185
<211>  152
<212>  PRT
<213>  homo sapiens

<400>  3185

Met Ser Thr Pro Ala Arg Arg Arg Leu Met Arg Asp Phe Lys Arg Leu 
1               5                   10                  15      


Gln Glu Asp Pro Pro Ala Gly Val Ser Gly Ala Pro Ser Glu Asn Asn 
            20                  25                  30          


Ile Met Val Trp Asn Ala Val Ile Phe Gly Pro Glu Gly Thr Pro Phe 
        35                  40                  45              


Glu Asp Gly Thr Phe Lys Leu Thr Ile Glu Phe Thr Glu Glu Tyr Pro 
    50                  55                  60                  


Asn Lys Pro Pro Thr Val Arg Phe Val Ser Lys Met Phe His Pro Asn 
65                  70                  75                  80  


Val Tyr Ala Asp Gly Ser Ile Cys Leu Asp Ile Leu Gln Asn Arg Trp 
                85                  90                  95      


Ser Pro Thr Tyr Asp Val Ser Ser Ile Leu Thr Ser Ile Gln Ser Leu 
            100                 105                 110         


Leu Asp Glu Pro Asn Pro Asn Ser Pro Ala Asn Ser Gln Ala Ala Gln 
        115                 120                 125             


Leu Tyr Gln Glu Asn Lys Arg Glu Tyr Glu Lys Arg Val Ser Ala Ile 
    130                 135                 140                 


Val Glu Gln Ser Trp Arg Asp Cys 
145                 150         


<210>  3186
<211>  179
<212>  PRT
<213>  homo sapiens

<400>  3186

Met Ala Ser Gln Asn Arg Asp Pro Ala Ala Thr Ser Val Ala Ala Ala 
1               5                   10                  15      


Arg Lys Gly Ala Glu Pro Ser Gly Gly Ala Ala Arg Gly Pro Val Gly 
            20                  25                  30          


Lys Arg Leu Gln Gln Glu Leu Met Thr Leu Met Met Ser Gly Asp Lys 
        35                  40                  45              


Gly Ile Ser Ala Phe Pro Glu Ser Asp Asn Leu Phe Lys Trp Val Gly 
    50                  55                  60                  


Thr Ile His Gly Ala Ala Gly Thr Val Tyr Glu Asp Leu Arg Tyr Lys 
65                  70                  75                  80  


Leu Ser Leu Glu Phe Pro Ser Gly Tyr Pro Tyr Asn Ala Pro Thr Val 
                85                  90                  95      


Lys Phe Leu Thr Pro Cys Tyr His Pro Asn Val Asp Thr Gln Gly Asn 
            100                 105                 110         


Ile Cys Leu Asp Ile Leu Lys Glu Lys Trp Ser Ala Leu Tyr Asp Val 
        115                 120                 125             


Arg Thr Ile Leu Leu Ser Ile Gln Ser Leu Leu Gly Glu Pro Asn Ile 
    130                 135                 140                 


Asp Ser Pro Leu Asn Thr His Ala Ala Glu Leu Trp Lys Asn Pro Thr 
145                 150                 155                 160 


Ala Phe Lys Lys Tyr Leu Gln Glu Thr Tyr Ser Lys Gln Val Thr Ser 
                165                 170                 175     


Gln Glu Pro 
            


<210>  3187
<211>  161
<212>  PRT
<213>  homo sapiens

<400>  3187

Met Ala Ser Gln Asn Arg Asp Pro Ala Ala Thr Ser Val Ala Ala Ala 
1               5                   10                  15      


Arg Lys Gly Ala Glu Pro Ser Gly Gly Ala Ala Arg Gly Pro Val Gly 
            20                  25                  30          


Lys Arg Leu Gln Gln Glu Leu Met Thr Leu Met Met Ser Gly Asp Lys 
        35                  40                  45              


Gly Ile Ser Ala Phe Pro Glu Ser Asp Asn Leu Phe Lys Trp Val Gly 
    50                  55                  60                  


Thr Ile His Gly Ala Ala Gly Thr Ala Val Gly Ser Ile Arg Thr Ser 
65                  70                  75                  80  


Ser Thr Val Cys Leu Leu Ser Gly Pro Arg Glu Thr Gln Asp Ser Ser 
                85                  90                  95      


Lys Pro Leu Val Trp Gly Leu Gly Trp Asp Met Arg Leu Leu Leu Glu 
            100                 105                 110         


Leu Thr Leu Gln Leu Phe Leu Gln Met Pro Glu Pro Asn Ile Asp Ser 
        115                 120                 125             


Pro Leu Asn Thr His Ala Ala Glu Leu Trp Lys Asn Pro Thr Ala Phe 
    130                 135                 140                 


Lys Lys Tyr Leu Gln Glu Thr Tyr Ser Lys Gln Val Thr Ser Gln Glu 
145                 150                 155                 160 


Pro 
    


<210>  3188
<211>  114
<212>  PRT
<213>  homo sapiens

<400>  3188

Met Gly Pro Arg Arg Arg Ser Arg Lys Pro Glu Ala Pro Arg Arg Arg 
1               5                   10                  15      


Ser Pro Ser Pro Thr Pro Thr Pro Gly Pro Ser Arg Arg Gly Pro Ser 
            20                  25                  30          


Leu Gly Ala Ser Ser His Gln His Ser Arg Arg Arg Gln Gly Trp Leu 
        35                  40                  45              


Lys Glu Ile Arg Lys Leu Gln Lys Ser Thr His Leu Leu Ile Arg Lys 
    50                  55                  60                  


Leu Pro Phe Ser Arg Leu Ala Ala Glu Ala Phe Leu Val His Leu Phe 
65                  70                  75                  80  


Glu Asp Ala Tyr Leu Leu Thr Leu His Ala Gly Arg Val Thr Leu Phe 
                85                  90                  95      


Pro Lys Asp Val Gln Leu Ala Arg Arg Ile Arg Gly Leu Glu Glu Gly 
            100                 105                 110         


Leu Gly 
        


<210>  3189
<211>  781
<212>  PRT
<213>  homo sapiens

<400>  3189

Met Ala Thr Gln Ala Asp Leu Met Glu Leu Asp Met Ala Met Glu Pro 
1               5                   10                  15      


Asp Arg Lys Ala Ala Val Ser His Trp Gln Gln Gln Ser Tyr Leu Asp 
            20                  25                  30          


Ser Gly Ile His Ser Gly Ala Thr Thr Thr Ala Pro Ser Leu Ser Gly 
        35                  40                  45              


Lys Gly Asn Pro Glu Glu Glu Asp Val Asp Thr Ser Gln Val Leu Tyr 
    50                  55                  60                  


Glu Trp Glu Gln Gly Phe Ser Gln Ser Phe Thr Gln Glu Gln Val Ala 
65                  70                  75                  80  


Asp Ile Asp Gly Gln Tyr Ala Met Thr Arg Ala Gln Arg Val Arg Ala 
                85                  90                  95      


Ala Met Phe Pro Glu Thr Leu Asp Glu Gly Met Gln Ile Pro Ser Thr 
            100                 105                 110         


Gln Phe Asp Ala Ala His Pro Thr Asn Val Gln Arg Leu Ala Glu Pro 
        115                 120                 125             


Ser Gln Met Leu Lys His Ala Val Val Asn Leu Ile Asn Tyr Gln Asp 
    130                 135                 140                 


Asp Ala Glu Leu Ala Thr Arg Ala Ile Pro Glu Leu Thr Lys Leu Leu 
145                 150                 155                 160 


Asn Asp Glu Asp Gln Val Val Val Asn Lys Ala Ala Val Met Val His 
                165                 170                 175     


Gln Leu Ser Lys Lys Glu Ala Ser Arg His Ala Ile Met Arg Ser Pro 
            180                 185                 190         


Gln Met Val Ser Ala Ile Val Arg Thr Met Gln Asn Thr Asn Asp Val 
        195                 200                 205             


Glu Thr Ala Arg Cys Thr Ala Gly Thr Leu His Asn Leu Ser His His 
    210                 215                 220                 


Arg Glu Gly Leu Leu Ala Ile Phe Lys Ser Gly Gly Ile Pro Ala Leu 
225                 230                 235                 240 


Val Lys Met Leu Gly Ser Pro Val Asp Ser Val Leu Phe Tyr Ala Ile 
                245                 250                 255     


Thr Thr Leu His Asn Leu Leu Leu His Gln Glu Gly Ala Lys Met Ala 
            260                 265                 270         


Val Arg Leu Ala Gly Gly Leu Gln Lys Met Val Ala Leu Leu Asn Lys 
        275                 280                 285             


Thr Asn Val Lys Phe Leu Ala Ile Thr Thr Asp Cys Leu Gln Ile Leu 
    290                 295                 300                 


Ala Tyr Gly Asn Gln Glu Ser Lys Leu Ile Ile Leu Ala Ser Gly Gly 
305                 310                 315                 320 


Pro Gln Ala Leu Val Asn Ile Met Arg Thr Tyr Thr Tyr Glu Lys Leu 
                325                 330                 335     


Leu Trp Thr Thr Ser Arg Val Leu Lys Val Leu Ser Val Cys Ser Ser 
            340                 345                 350         


Asn Lys Pro Ala Ile Val Glu Ala Gly Gly Met Gln Ala Leu Gly Leu 
        355                 360                 365             


His Leu Thr Asp Pro Ser Gln Arg Leu Val Gln Asn Cys Leu Trp Thr 
    370                 375                 380                 


Leu Arg Asn Leu Ser Asp Ala Ala Thr Lys Gln Glu Gly Met Glu Gly 
385                 390                 395                 400 


Leu Leu Gly Thr Leu Val Gln Leu Leu Gly Ser Asp Asp Ile Asn Val 
                405                 410                 415     


Val Thr Cys Ala Ala Gly Ile Leu Ser Asn Leu Thr Cys Asn Asn Tyr 
            420                 425                 430         


Lys Asn Lys Met Met Val Cys Gln Val Gly Gly Ile Glu Ala Leu Val 
        435                 440                 445             


Arg Thr Val Leu Arg Ala Gly Asp Arg Glu Asp Ile Thr Glu Pro Ala 
    450                 455                 460                 


Ile Cys Ala Leu Arg His Leu Thr Ser Arg His Gln Glu Ala Glu Met 
465                 470                 475                 480 


Ala Gln Asn Ala Val Arg Leu His Tyr Gly Leu Pro Val Val Val Lys 
                485                 490                 495     


Leu Leu His Pro Pro Ser His Trp Pro Leu Ile Lys Ala Thr Val Gly 
            500                 505                 510         


Leu Ile Arg Asn Leu Ala Leu Cys Pro Ala Asn His Ala Pro Leu Arg 
        515                 520                 525             


Glu Gln Gly Ala Ile Pro Arg Leu Val Gln Leu Leu Val Arg Ala His 
    530                 535                 540                 


Gln Asp Thr Gln Arg Arg Thr Ser Met Gly Gly Thr Gln Gln Gln Phe 
545                 550                 555                 560 


Val Glu Gly Val Arg Met Glu Glu Ile Val Glu Gly Cys Thr Gly Ala 
                565                 570                 575     


Leu His Ile Leu Ala Arg Asp Val His Asn Arg Ile Val Ile Arg Gly 
            580                 585                 590         


Leu Asn Thr Ile Pro Leu Phe Val Gln Leu Leu Tyr Ser Pro Ile Glu 
        595                 600                 605             


Asn Ile Gln Arg Val Ala Ala Gly Val Leu Cys Glu Leu Ala Gln Asp 
    610                 615                 620                 


Lys Glu Ala Ala Glu Ala Ile Glu Ala Glu Gly Ala Thr Ala Pro Leu 
625                 630                 635                 640 


Thr Glu Leu Leu His Ser Arg Asn Glu Gly Val Ala Thr Tyr Ala Ala 
                645                 650                 655     


Ala Val Leu Phe Arg Met Ser Glu Asp Lys Pro Gln Asp Tyr Lys Lys 
            660                 665                 670         


Arg Leu Ser Val Glu Leu Thr Ser Ser Leu Phe Arg Thr Glu Pro Met 
        675                 680                 685             


Ala Trp Asn Glu Thr Ala Asp Leu Gly Leu Asp Ile Gly Ala Gln Gly 
    690                 695                 700                 


Glu Pro Leu Gly Tyr Arg Gln Asp Asp Pro Ser Tyr Arg Ser Phe His 
705                 710                 715                 720 


Ser Gly Gly Tyr Gly Gln Asp Ala Leu Gly Met Asp Pro Met Met Glu 
                725                 730                 735     


His Glu Met Gly Gly His His Pro Gly Ala Asp Tyr Pro Val Asp Gly 
            740                 745                 750         


Leu Pro Asp Leu Gly His Ala Gln Asp Leu Met Asp Gly Leu Pro Pro 
        755                 760                 765             


Gly Asp Ser Asn Gln Leu Ala Trp Phe Asp Thr Asp Leu 
    770                 775                 780     


<210>  3190
<211>  104
<212>  PRT
<213>  homo sapiens

<400>  3190

Met Glu Ala Pro Leu Val Ser Leu Asp Glu Glu Phe Glu Asp Leu Arg 
1               5                   10                  15      


Pro Ser Cys Ser Glu Asp Pro Glu Glu Lys Pro Gln Cys Phe Tyr Gly 
            20                  25                  30          


Ser Ser Pro His His Leu Glu Asp Pro Ser Leu Ser Glu Leu Glu Asn 
        35                  40                  45              


Phe Ser Ser Glu Ile Ile Ser Phe Lys Ser Met Glu Asp Leu Val Asn 
    50                  55                  60                  


Glu Phe Asp Glu Lys Leu Asn Val Cys Phe Arg Asn Tyr Asn Ala Lys 
65                  70                  75                  80  


Thr Glu Asn Leu Ala Pro Val Lys Asn Gln Leu Gln Ile Gln Glu Glu 
                85                  90                  95      


Glu Glu Thr Leu Gln Asp Glu Glu 
            100                 


<210>  3191
<211>  83
<212>  PRT
<213>  homo sapiens

<400>  3191

Met Ser Asp Asn Asp Asp Ile Glu Val Glu Ser Asp Glu Glu Gln Pro 
1               5                   10                  15      


Arg Phe Gln Ser Ala Ala Asp Lys Arg Ala His His Asn Ala Leu Glu 
            20                  25                  30          


Arg Lys Arg Arg Asp His Ile Lys Asp Ser Phe His Ser Leu Arg Asp 
        35                  40                  45              


Ser Val Pro Ser Leu Gln Gly Glu Lys Gly Thr Lys Met Lys Leu Thr 
    50                  55                  60                  


Leu Pro Pro Val Phe Pro Tyr Glu His Leu Pro Phe Pro Thr Val Phe 
65                  70                  75                  80  


Cys His Gly 
            


<210>  3192
<211>  493
<212>  PRT
<213>  homo sapiens

<400>  3192

Met Phe Pro Val Phe Pro Cys Thr Leu Leu Ala Pro Pro Phe Pro Val 
1               5                   10                  15      


Leu Gly Leu Asp Ser Arg Gly Val Gly Gly Leu Met Asn Ser Phe Pro 
            20                  25                  30          


Pro Pro Gln Gly His Ala Gln Asn Pro Leu Gln Val Gly Ala Glu Leu 
        35                  40                  45              


Gln Ser Arg Phe Phe Ala Ser Gln Gly Cys Ala Gln Ser Pro Phe Gln 
    50                  55                  60                  


Ala Ala Pro Ala Pro Pro Pro Thr Pro Gln Ala Pro Ala Ala Glu Pro 
65                  70                  75                  80  


Leu Gln Val Asp Leu Leu Pro Val Leu Ala Ala Ala Gln Glu Ser Ala 
                85                  90                  95      


Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Val Ala Ala Ala 
            100                 105                 110         


Pro Pro Ala Pro Ala Ala Ala Ser Thr Val Asp Thr Ala Ala Leu Lys 
        115                 120                 125             


Gln Pro Pro Ala Pro Pro Pro Pro Pro Pro Pro Val Ser Ala Pro Ala 
    130                 135                 140                 


Ala Glu Ala Ala Pro Pro Ala Ser Ala Ala Thr Ile Ala Ala Ala Ala 
145                 150                 155                 160 


Ala Thr Ala Val Val Ala Pro Thr Ser Thr Val Ala Val Ala Pro Val 
                165                 170                 175     


Ala Ser Ala Leu Glu Lys Lys Thr Lys Ser Lys Gly Pro Tyr Ile Cys 
            180                 185                 190         


Ala Leu Cys Ala Lys Glu Phe Lys Asn Gly Tyr Asn Leu Arg Arg His 
        195                 200                 205             


Glu Ala Ile His Thr Gly Ala Lys Ala Gly Arg Val Pro Ser Gly Ala 
    210                 215                 220                 


Met Lys Met Pro Thr Met Val Pro Leu Ser Leu Leu Ser Val Pro Gln 
225                 230                 235                 240 


Leu Ser Gly Ala Gly Gly Gly Gly Gly Glu Ala Gly Ala Gly Gly Gly 
                245                 250                 255     


Ala Ala Ala Val Ala Ala Gly Gly Val Val Thr Thr Thr Ala Ser Gly 
            260                 265                 270         


Lys Arg Ile Arg Lys Asn His Ala Cys Glu Met Cys Gly Lys Ala Phe 
        275                 280                 285             


Arg Asp Val Tyr His Leu Asn Arg His Lys Leu Ser His Ser Asp Glu 
    290                 295                 300                 


Lys Pro Tyr Gln Cys Pro Val Cys Gln Gln Arg Phe Lys Arg Lys Asp 
305                 310                 315                 320 


Arg Met Ser Tyr His Val Arg Ser His Asp Gly Ala Val His Lys Pro 
                325                 330                 335     


Tyr Asn Cys Ser His Cys Gly Lys Ser Phe Ser Arg Pro Asp His Leu 
            340                 345                 350         


Asn Ser His Val Arg Gln Val His Ser Thr Glu Arg Pro Phe Lys Cys 
        355                 360                 365             


Glu Lys Cys Glu Ala Ala Phe Ala Thr Lys Asp Arg Leu Arg Ala His 
    370                 375                 380                 


Thr Val Arg His Glu Glu Lys Val Pro Cys His Val Cys Gly Lys Met 
385                 390                 395                 400 


Leu Ser Ser Ala Tyr Ile Ser Asp His Met Lys Val His Ser Gln Gly 
                405                 410                 415     


Pro His His Val Cys Glu Leu Cys Asn Lys Gly Phe Thr Thr Ala Ala 
            420                 425                 430         


Tyr Leu Arg Ile His Ala Val Lys Asp His Gly Leu Gln Ala Pro Arg 
        435                 440                 445             


Ala Asp Arg Ile Leu Cys Lys Leu Cys Ser Val His Cys Lys Thr Pro 
    450                 455                 460                 


Ala Gln Leu Ala Gly His Met Gln Thr His Leu Gly Gly Ala Ala Pro 
465                 470                 475                 480 


Pro Val Pro Gly Asp Ala Pro Gln Pro Gln Pro Thr Cys 
                485                 490             


<210>  3193
<211>  599
<212>  PRT
<213>  homo sapiens

<400>  3193

Met Gly Pro Lys Arg Arg Gln Leu Thr Phe Arg Glu Lys Ser Arg Ile 
1               5                   10                  15      


Ile Gln Glu Val Glu Glu Asn Pro Asp Leu Arg Lys Gly Glu Ile Ala 
            20                  25                  30          


Arg Arg Phe Asn Ile Pro Pro Ser Thr Leu Ser Thr Ile Leu Lys Asn 
        35                  40                  45              


Lys Arg Ala Ile Leu Ala Ser Glu Arg Lys Tyr Gly Val Ala Ser Thr 
    50                  55                  60                  


Cys Arg Lys Thr Asn Lys Leu Ser Pro Tyr Asp Lys Leu Glu Gly Leu 
65                  70                  75                  80  


Leu Ile Ala Trp Phe Gln Gln Ile Arg Ala Ala Gly Leu Pro Val Lys 
                85                  90                  95      


Gly Ile Ile Leu Lys Glu Lys Ala Leu Arg Ile Ala Glu Glu Leu Gly 
            100                 105                 110         


Met Asp Asp Phe Thr Ala Ser Asn Gly Trp Leu Asp Arg Phe Arg Arg 
        115                 120                 125             


Arg His Gly Val Val Ser Cys Ser Gly Val Ala Arg Ala Arg Ala Arg 
    130                 135                 140                 


Asn Ala Ala Pro Arg Thr Pro Ala Ala Pro Ala Ser Pro Ala Ala Val 
145                 150                 155                 160 


Pro Ser Glu Gly Ser Gly Gly Ser Thr Thr Gly Trp Arg Ala Arg Glu 
                165                 170                 175     


Glu Gln Pro Pro Ser Val Ala Glu Gly Tyr Ala Ser Gln Asp Val Phe 
            180                 185                 190         


Ser Ala Thr Glu Thr Ser Leu Trp Tyr Asp Phe Leu Pro Asp Gln Ala 
        195                 200                 205             


Ala Gly Leu Cys Gly Gly Asp Gly Arg Pro Arg Gln Ala Thr Gln Arg 
    210                 215                 220                 


Leu Ser Val Leu Leu Cys Ala Asn Ala Asp Gly Ser Glu Lys Leu Pro 
225                 230                 235                 240 


Pro Leu Val Ala Gly Lys Ser Ala Lys Pro Arg Ala Gly Gln Ala Gly 
                245                 250                 255     


Leu Pro Cys Asp Tyr Thr Ala Asn Ser Lys Gly Gly Val Thr Thr Gln 
            260                 265                 270         


Ala Leu Ala Lys Tyr Leu Lys Ala Leu Asp Thr Arg Met Ala Ala Glu 
        275                 280                 285             


Ser Arg Arg Val Leu Leu Leu Ala Gly Arg Leu Ala Ala Gln Ser Leu 
    290                 295                 300                 


Asp Thr Ser Gly Leu Arg His Val Gln Leu Ala Phe Phe Pro Pro Gly 
305                 310                 315                 320 


Thr Val His Pro Leu Glu Arg Gly Val Val Gln Gln Val Lys Gly His 
                325                 330                 335     


Tyr Arg Gln Ala Met Leu Leu Lys Ala Met Ala Ala Leu Glu Gly Gln 
            340                 345                 350         


Asp Pro Ser Gly Leu Gln Leu Gly Leu Thr Glu Ala Leu His Phe Val 
        355                 360                 365             


Ala Ala Ala Trp Gln Ala Val Glu Pro Ser Asp Ile Ala Ala Cys Phe 
    370                 375                 380                 


Arg Glu Ala Gly Phe Gly Gly Gly Pro Asn Ala Thr Ile Thr Thr Ser 
385                 390                 395                 400 


Leu Lys Ser Glu Gly Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu 
                405                 410                 415     


Glu Glu Glu Gly Glu Gly Glu Glu Glu Glu Glu Glu Gly Glu Glu Glu 
            420                 425                 430         


Glu Glu Glu Gly Gly Glu Gly Glu Glu Leu Gly Glu Glu Glu Glu Val 
        435                 440                 445             


Glu Glu Glu Gly Asp Val Asp Ser Asp Glu Glu Glu Glu Glu Asp Glu 
    450                 455                 460                 


Glu Ser Ser Ser Glu Gly Leu Glu Ala Glu Asp Trp Ala Gln Gly Val 
465                 470                 475                 480 


Val Glu Ala Gly Gly Ser Phe Gly Ala Tyr Gly Ala Gln Glu Glu Ala 
                485                 490                 495     


Gln Cys Pro Thr Leu His Phe Leu Glu Gly Gly Glu Asp Ser Asp Ser 
            500                 505                 510         


Asp Ser Glu Glu Glu Asp Asp Glu Glu Glu Asp Asp Glu Asp Glu Asp 
        515                 520                 525             


Asp Asp Asp Asp Glu Glu Asp Gly Asp Glu Val Pro Val Pro Ser Phe 
    530                 535                 540                 


Gly Glu Ala Met Ala Tyr Phe Ala Met Val Lys Arg Tyr Leu Thr Ser 
545                 550                 555                 560 


Phe Pro Ile Asp Asp Arg Val Gln Ser His Ile Leu His Leu Glu His 
                565                 570                 575     


Asp Leu Val His Val Thr Arg Lys Asn His Ala Arg Gln Ala Gly Val 
            580                 585                 590         


Arg Gly Leu Gly His Gln Ser 
        595                 


<210>  3194
<211>  399
<212>  PRT
<213>  homo sapiens

<400>  3194

Met Lys Met Arg Phe Leu Gly Leu Val Val Cys Leu Val Leu Trp Thr 
1               5                   10                  15      


Leu His Ser Glu Gly Ser Gly Gly Lys Leu Thr Ala Val Asp Pro Glu 
            20                  25                  30          


Thr Asn Met Asn Val Ser Glu Ile Ile Ser Tyr Trp Gly Phe Pro Ser 
        35                  40                  45              


Glu Glu Tyr Leu Val Glu Thr Glu Asp Gly Tyr Ile Leu Cys Leu Asn 
    50                  55                  60                  


Arg Ile Pro His Gly Arg Lys Asn His Ser Asp Lys Gly Pro Lys Pro 
65                  70                  75                  80  


Val Val Phe Leu Gln His Gly Leu Leu Ala Asp Ser Ser Asn Trp Val 
                85                  90                  95      


Thr Asn Leu Ala Asn Ser Ser Leu Gly Phe Ile Leu Ala Asp Ala Gly 
            100                 105                 110         


Phe Asp Val Trp Met Gly Asn Ser Arg Gly Asn Thr Trp Ser Arg Lys 
        115                 120                 125             


His Lys Thr Leu Ser Val Ser Gln Asp Glu Phe Trp Ala Phe Ser Tyr 
    130                 135                 140                 


Asp Glu Met Ala Lys Tyr Asp Leu Pro Ala Ser Ile Asn Phe Ile Leu 
145                 150                 155                 160 


Asn Lys Thr Gly Gln Glu Gln Val Tyr Tyr Val Gly His Ser Gln Gly 
                165                 170                 175     


Thr Thr Ile Gly Phe Ile Ala Phe Ser Gln Ile Pro Glu Leu Ala Lys 
            180                 185                 190         


Arg Ile Lys Met Phe Phe Ala Leu Gly Pro Val Ala Ser Val Ala Phe 
        195                 200                 205             


Cys Thr Ser Pro Met Ala Lys Leu Gly Arg Leu Pro Asp His Leu Ile 
    210                 215                 220                 


Lys Asp Leu Phe Gly Asp Lys Glu Phe Leu Pro Gln Ser Ala Phe Leu 
225                 230                 235                 240 


Lys Trp Leu Gly Thr His Val Cys Thr His Val Ile Leu Lys Glu Leu 
                245                 250                 255     


Cys Gly Asn Leu Cys Phe Leu Leu Cys Gly Phe Asn Glu Arg Asn Leu 
            260                 265                 270         


Asn Met Ser Arg Val Asp Val Tyr Thr Thr His Ser Pro Ala Gly Thr 
        275                 280                 285             


Ser Val Gln Asn Met Leu His Trp Ser Gln Ala Val Lys Phe Gln Lys 
    290                 295                 300                 


Phe Gln Ala Phe Asp Trp Gly Ser Ser Ala Lys Asn Tyr Phe His Tyr 
305                 310                 315                 320 


Asn Gln Ser Tyr Pro Pro Thr Tyr Asn Val Lys Asp Met Leu Val Pro 
                325                 330                 335     


Thr Ala Val Trp Ser Gly Gly His Asp Trp Leu Ala Asp Val Tyr Asp 
            340                 345                 350         


Val Asn Ile Leu Leu Thr Gln Ile Thr Asn Leu Val Phe His Glu Ser 
        355                 360                 365             


Ile Pro Glu Trp Glu His Leu Asp Phe Ile Trp Gly Leu Asp Ala Pro 
    370                 375                 380                 


Trp Arg Leu Tyr Asn Lys Ile Ile Asn Leu Met Arg Lys Tyr Gln 
385                 390                 395                 


<210>  3195
<211>  1690
<212>  PRT
<213>  homo sapiens

<400>  3195

Met Ala Gly Ala Ser Val Lys Val Ala Val Arg Val Arg Pro Phe Asn 
1               5                   10                  15      


Ser Arg Glu Met Ser Arg Asp Ser Lys Cys Ile Ile Gln Met Ser Gly 
            20                  25                  30          


Ser Thr Thr Thr Ile Val Asn Pro Lys Gln Pro Lys Glu Thr Pro Lys 
        35                  40                  45              


Ser Phe Ser Phe Asp Tyr Ser Tyr Trp Ser His Thr Ser Pro Glu Asp 
    50                  55                  60                  


Ile Asn Tyr Ala Ser Gln Lys Gln Val Tyr Arg Asp Ile Gly Glu Glu 
65                  70                  75                  80  


Met Leu Gln His Ala Phe Glu Gly Tyr Asn Val Cys Ile Phe Ala Tyr 
                85                  90                  95      


Gly Gln Thr Gly Ala Gly Lys Ser Tyr Thr Met Met Gly Lys Gln Glu 
            100                 105                 110         


Lys Asp Gln Gln Gly Ile Ile Pro Gln Leu Cys Glu Asp Leu Phe Ser 
        115                 120                 125             


Arg Ile Asn Asp Thr Thr Asn Asp Asn Met Ser Tyr Ser Val Glu Val 
    130                 135                 140                 


Ser Tyr Met Glu Ile Tyr Cys Glu Arg Val Arg Asp Leu Leu Asn Pro 
145                 150                 155                 160 


Lys Asn Lys Gly Asn Leu Arg Val Arg Glu His Pro Leu Leu Gly Pro 
                165                 170                 175     


Tyr Val Glu Asp Leu Ser Lys Leu Ala Val Thr Ser Tyr Asn Asp Ile 
            180                 185                 190         


Gln Asp Leu Met Asp Ser Gly Asn Lys Ala Arg Thr Val Ala Ala Thr 
        195                 200                 205             


Asn Met Asn Glu Thr Ser Ser Arg Ser His Ala Val Phe Asn Ile Ile 
    210                 215                 220                 


Phe Thr Gln Lys Arg His Asp Ala Glu Thr Asn Ile Thr Thr Glu Lys 
225                 230                 235                 240 


Val Ser Lys Ile Ser Leu Val Asp Leu Ala Gly Ser Glu Arg Ala Asp 
                245                 250                 255     


Ser Thr Gly Ala Lys Gly Thr Arg Leu Lys Glu Gly Ala Asn Ile Asn 
            260                 265                 270         


Lys Ser Leu Thr Thr Leu Gly Lys Val Ile Ser Ala Leu Ala Glu Met 
        275                 280                 285             


Asp Ser Gly Pro Asn Lys Asn Lys Lys Lys Lys Lys Thr Asp Phe Ile 
    290                 295                 300                 


Pro Tyr Arg Asp Ser Val Leu Thr Trp Leu Leu Arg Glu Asn Leu Gly 
305                 310                 315                 320 


Gly Asn Ser Arg Thr Ala Met Val Ala Ala Leu Ser Pro Ala Asp Ile 
                325                 330                 335     


Asn Tyr Asp Glu Thr Leu Ser Thr Leu Arg Tyr Ala Asp Arg Ala Lys 
            340                 345                 350         


Gln Ile Arg Cys Asn Ala Val Ile Asn Glu Asp Pro Asn Asn Lys Leu 
        355                 360                 365             


Ile Arg Glu Leu Lys Asp Glu Val Thr Arg Leu Arg Asp Leu Leu Tyr 
    370                 375                 380                 


Ala Gln Gly Leu Gly Asp Ile Thr Asp Met Thr Asn Ala Leu Val Gly 
385                 390                 395                 400 


Met Ser Pro Ser Ser Ser Leu Ser Ala Leu Ser Ser Arg Ala Ala Ser 
                405                 410                 415     


Val Ser Ser Leu His Glu Arg Ile Leu Phe Ala Pro Gly Ser Glu Glu 
            420                 425                 430         


Ala Ile Glu Arg Leu Lys Glu Thr Glu Lys Ile Ile Ala Glu Leu Asn 
        435                 440                 445             


Glu Thr Trp Glu Glu Lys Leu Arg Arg Thr Glu Ala Ile Arg Met Glu 
    450                 455                 460                 


Arg Glu Ala Leu Leu Ala Glu Met Gly Val Ala Met Arg Glu Asp Gly 
465                 470                 475                 480 


Gly Thr Leu Gly Val Phe Ser Pro Lys Lys Thr Pro His Leu Val Asn 
                485                 490                 495     


Leu Asn Glu Asp Pro Leu Met Ser Glu Cys Leu Leu Tyr Tyr Ile Lys 
            500                 505                 510         


Asp Gly Ile Thr Arg Val Gly Arg Glu Asp Gly Glu Arg Arg Gln Asp 
        515                 520                 525             


Ile Val Leu Ser Gly His Phe Ile Lys Glu Glu His Cys Val Phe Arg 
    530                 535                 540                 


Ser Asp Ser Arg Gly Gly Ser Glu Ala Val Val Thr Leu Glu Pro Cys 
545                 550                 555                 560 


Glu Gly Ala Asp Thr Tyr Val Asn Gly Lys Lys Val Thr Glu Pro Ser 
                565                 570                 575     


Ile Leu Arg Ser Gly Asn Arg Ile Ile Met Gly Lys Ser His Val Phe 
            580                 585                 590         


Arg Phe Asn His Pro Glu Gln Ala Arg Gln Glu Arg Glu Arg Thr Pro 
        595                 600                 605             


Cys Ala Glu Thr Pro Ala Glu Pro Val Asp Trp Ala Phe Ala Gln Arg 
    610                 615                 620                 


Glu Leu Leu Glu Lys Gln Gly Ile Asp Met Lys Gln Glu Met Glu Gln 
625                 630                 635                 640 


Arg Leu Gln Glu Leu Glu Asp Gln Tyr Arg Arg Glu Arg Glu Glu Ala 
                645                 650                 655     


Thr Tyr Leu Leu Glu Gln Gln Arg Leu Asp Tyr Glu Ser Lys Leu Glu 
            660                 665                 670         


Ala Leu Gln Lys Gln Met Asp Ser Arg Tyr Tyr Pro Glu Val Asn Glu 
        675                 680                 685             


Glu Glu Glu Glu Pro Glu Asp Glu Val Gln Trp Thr Glu Arg Glu Cys 
    690                 695                 700                 


Glu Leu Ala Leu Trp Ala Phe Arg Lys Trp Lys Trp Tyr Gln Phe Thr 
705                 710                 715                 720 


Ser Leu Arg Asp Leu Leu Trp Gly Asn Ala Ile Phe Leu Lys Glu Ala 
                725                 730                 735     


Asn Ala Ile Ser Val Glu Leu Lys Lys Lys Val Gln Phe Gln Phe Val 
            740                 745                 750         


Leu Leu Thr Asp Thr Leu Tyr Ser Pro Leu Pro Pro Asp Leu Leu Pro 
        755                 760                 765             


Pro Glu Ala Ala Lys Asp Arg Glu Thr Arg Pro Phe Pro Arg Thr Ile 
    770                 775                 780                 


Val Ala Val Glu Val Gln Asp Gln Lys Asn Gly Ala Thr His Tyr Trp 
785                 790                 795                 800 


Thr Leu Glu Lys Leu Arg Gln Arg Leu Asp Leu Met Arg Glu Met Tyr 
                805                 810                 815     


Asp Arg Ala Ala Glu Val Pro Ser Ser Val Ile Glu Asp Cys Asp Asn 
            820                 825                 830         


Val Val Thr Gly Gly Asp Pro Phe Tyr Asp Arg Phe Pro Trp Phe Arg 
        835                 840                 845             


Leu Val Gly Arg Ala Phe Val Tyr Leu Ser Asn Leu Leu Tyr Pro Val 
    850                 855                 860                 


Pro Leu Val His Arg Val Ala Ile Val Ser Glu Lys Gly Glu Val Lys 
865                 870                 875                 880 


Gly Phe Leu Arg Val Ala Val Gln Ala Ile Ser Ala Asp Glu Glu Ala 
                885                 890                 895     


Pro Asp Tyr Gly Ser Gly Val Arg Gln Ser Gly Thr Ala Lys Ile Ser 
            900                 905                 910         


Phe Asp Asp Gln His Phe Glu Lys Phe Gln Ser Glu Ser Cys Pro Val 
        915                 920                 925             


Val Gly Met Ser Arg Ser Gly Thr Ser Gln Glu Glu Leu Arg Ile Val 
    930                 935                 940                 


Glu Gly Gln Gly Gln Gly Ala Asp Val Gly Pro Ser Ala Asp Glu Val 
945                 950                 955                 960 


Asn Asn Asn Thr Cys Ser Ala Val Pro Pro Glu Gly Leu Leu Leu Asp 
                965                 970                 975     


Ser Ser Glu Lys Ala Ala Leu Asp Gly Pro Leu Asp Ala Ala Leu Asp 
            980                 985                 990         


His Leu Arg Leu Gly Asn Thr Phe  Thr Phe Arg Val Thr  Val Leu Gln 
        995                 1000                 1005             


Ala Ser  Ser Ile Ser Ala Glu  Tyr Ala Asp Ile Phe  Cys Gln Phe 
    1010                 1015                 1020             


Asn Phe  Ile His Arg His Asp  Glu Ala Phe Ser Thr  Glu Pro Leu 
    1025                 1030                 1035             


Lys Asn  Thr Gly Arg Gly Pro  Pro Leu Gly Phe Tyr  His Val Gln 
    1040                 1045                 1050             


Asn Ile  Ala Val Glu Val Thr  Lys Ser Phe Ile Glu  Tyr Ile Lys 
    1055                 1060                 1065             


Ser Gln  Pro Ile Val Phe Glu  Val Phe Gly His Tyr  Gln Gln His 
    1070                 1075                 1080             


Pro Phe  Pro Pro Leu Cys Lys  Asp Val Leu Ser Pro  Leu Arg Pro 
    1085                 1090                 1095             


Ser Arg  Arg His Phe Pro Arg  Val Met Pro Leu Ser  Lys Pro Val 
    1100                 1105                 1110             


Pro Ala  Thr Lys Leu Ser Thr  Leu Thr Arg Pro Cys  Pro Gly Pro 
    1115                 1120                 1125             


Cys His  Cys Lys Tyr Asp Leu  Leu Val Tyr Phe Glu  Ile Cys Glu 
    1130                 1135                 1140             


Leu Glu  Ala Asn Gly Asp Tyr  Ile Pro Ala Val Val  Asp His Arg 
    1145                 1150                 1155             


Gly Gly  Met Pro Cys Met Gly  Thr Phe Leu Leu His  Gln Gly Ile 
    1160                 1165                 1170             


Gln Arg  Arg Ile Thr Val Thr  Leu Leu His Glu Thr  Gly Ser His 
    1175                 1180                 1185             


Ile Arg  Trp Lys Glu Val Arg  Glu Leu Val Val Gly  Arg Ile Arg 
    1190                 1195                 1200             


Asn Thr  Pro Glu Thr Asp Glu  Ser Leu Ile Asp Pro  Asn Ile Leu 
    1205                 1210                 1215             


Ser Leu  Asn Ile Leu Ser Ser  Gly Tyr Ile His Pro  Ala Gln Asp 
    1220                 1225                 1230             


Asp Arg  Thr Phe Tyr Gln Phe  Glu Ala Ala Trp Asp  Ser Ser Met 
    1235                 1240                 1245             


His Asn  Ser Leu Leu Leu Asn  Arg Val Thr Pro Tyr  Arg Glu Lys 
    1250                 1255                 1260             


Ile Tyr  Met Thr Leu Ser Ala  Tyr Ile Glu Met Glu  Asn Cys Thr 
    1265                 1270                 1275             


Gln Pro  Ala Val Val Thr Lys  Asp Phe Cys Met Val  Phe Tyr Ser 
    1280                 1285                 1290             


Arg Asp  Ala Lys Leu Pro Ala  Ser Arg Ser Ile Arg  Asn Leu Phe 
    1295                 1300                 1305             


Gly Ser  Gly Ser Leu Arg Ala  Ser Glu Ser Asn Arg  Val Thr Gly 
    1310                 1315                 1320             


Val Tyr  Glu Leu Ser Leu Cys  His Val Ala Asp Ala  Gly Ser Pro 
    1325                 1330                 1335             


Gly Met  Gln Arg Arg Arg Arg  Arg Val Leu Asp Thr  Ser Val Ala 
    1340                 1345                 1350             


Tyr Val  Arg Gly Glu Glu Asn  Leu Ala Gly Trp Arg  Pro Arg Ser 
    1355                 1360                 1365             


Asp Ser  Leu Ile Leu Asp His  Gln Trp Glu Leu Glu  Lys Leu Ser 
    1370                 1375                 1380             


Leu Leu  Gln Glu Val Glu Lys  Thr Arg His Tyr Leu  Leu Leu Arg 
    1385                 1390                 1395             


Glu Lys  Leu Glu Thr Ala Gln  Arg Pro Val Pro Glu  Ala Leu Ser 
    1400                 1405                 1410             


Pro Ala  Phe Ser Glu Asp Ser  Glu Ser His Gly Ser  Ser Ser Ala 
    1415                 1420                 1425             


Ser Ser  Pro Leu Ser Ala Glu  Gly Arg Pro Ser Pro  Leu Glu Ala 
    1430                 1435                 1440             


Pro Asn  Glu Arg Gln Arg Glu  Leu Ala Val Lys Cys  Leu Arg Leu 
    1445                 1450                 1455             


Leu Thr  His Thr Phe Asn Arg  Glu Tyr Thr His Ser  His Val Cys 
    1460                 1465                 1470             


Val Ser  Ala Ser Glu Ser Lys  Leu Ser Glu Met Ser  Val Thr Leu 
    1475                 1480                 1485             


Leu Arg  Asp Pro Ser Met Ser  Pro Leu Gly Val Ala  Thr Leu Thr 
    1490                 1495                 1500             


Pro Ser  Ser Thr Cys Pro Ser  Leu Val Glu Gly Arg  Tyr Gly Ala 
    1505                 1510                 1515             


Thr Asp  Leu Arg Thr Pro Gln  Pro Cys Ser Arg Pro  Ala Ser Pro 
    1520                 1525                 1530             


Glu Pro  Glu Leu Leu Pro Glu  Ala Asp Ser Lys Lys  Leu Pro Ser 
    1535                 1540                 1545             


Pro Ala  Arg Ala Thr Glu Thr  Asp Lys Glu Pro Gln  Arg Leu Leu 
    1550                 1555                 1560             


Val Pro  Asp Ile Gln Glu Ile  Arg Val Ser Pro Ile  Val Ser Lys 
    1565                 1570                 1575             


Lys Gly  Tyr Leu His Phe Leu  Glu Pro His Thr Ser  Gly Trp Ala 
    1580                 1585                 1590             


Arg Arg  Phe Val Val Val Arg  Arg Pro Tyr Ala Tyr  Met Tyr Asn 
    1595                 1600                 1605             


Ser Asp  Lys Asp Thr Val Glu  Arg Phe Val Leu Asn  Leu Ala Thr 
    1610                 1615                 1620             


Ala Gln  Val Glu Tyr Ser Glu  Asp Gln Gln Ala Met  Leu Lys Thr 
    1625                 1630                 1635             


Pro Asn  Thr Phe Ala Val Cys  Thr Glu His Arg Gly  Ile Leu Leu 
    1640                 1645                 1650             


Gln Ala  Ala Ser Asp Lys Asp  Met His Asp Trp Leu  Tyr Ala Phe 
    1655                 1660                 1665             


Asn Pro  Leu Leu Ala Gly Thr  Ile Arg Ser Lys Leu  Ser Arg Arg 
    1670                 1675                 1680             


Arg Ser  Ala Gln Met Arg Val  
    1685                 1690 


<210>  3196
<211>  265
<212>  PRT
<213>  homo sapiens

<400>  3196

Met Asp Gly Pro Ala Ile Ile Thr Gln Val Thr Asn Pro Lys Glu Asp 
1               5                   10                  15      


Glu Gly Arg Leu Pro Gly Ala Gly Glu Lys Ala Ser Gln Cys Asn Val 
            20                  25                  30          


Ser Leu Lys Lys Gln Arg Ser Arg Ser Ile Leu Ser Ser Phe Phe Cys 
        35                  40                  45              


Cys Phe Arg Asp Tyr Asn Val Glu Ala Pro Pro Pro Ser Ser Pro Ser 
    50                  55                  60                  


Val Leu Pro Pro Leu Val Glu Glu Asn Gly Gly Leu Gln Lys Pro Pro 
65                  70                  75                  80  


Ala Lys Tyr Leu Leu Pro Glu Val Thr Val Leu Asp Tyr Gly Lys Lys 
                85                  90                  95      


Cys Val Val Ile Asp Leu Asp Glu Thr Leu Val His Ser Ser Phe Lys 
            100                 105                 110         


Pro Ile Ser Asn Ala Asp Phe Ile Val Pro Val Glu Ile Asp Gly Thr 
        115                 120                 125             


Ile His Gln Val Tyr Val Leu Lys Arg Pro His Val Asp Glu Phe Leu 
    130                 135                 140                 


Gln Arg Met Gly Gln Leu Phe Glu Cys Val Leu Phe Thr Ala Ser Leu 
145                 150                 155                 160 


Ala Lys Tyr Ala Asp Pro Val Ala Asp Leu Leu Asp Arg Trp Gly Val 
                165                 170                 175     


Phe Arg Ala Arg Leu Phe Arg Glu Ser Cys Val Phe His Arg Gly Asn 
            180                 185                 190         


Tyr Val Lys Asp Leu Ser Arg Leu Gly Arg Glu Leu Ser Lys Val Ile 
        195                 200                 205             


Ile Val Asp Asn Ser Pro Ala Ser Tyr Ile Phe His Pro Glu Asn Ala 
    210                 215                 220                 


Val Pro Val Gln Ser Trp Phe Asp Asp Met Thr Asp Thr Glu Leu Leu 
225                 230                 235                 240 


Asp Leu Ile Pro Phe Phe Glu Gly Leu Ser Arg Glu Asp Asp Val Tyr 
                245                 250                 255     


Ser Met Leu His Arg Leu Cys Asn Arg 
            260                 265 


<210>  3197
<211>  276
<212>  PRT
<213>  homo sapiens

<400>  3197

Met Asp Gly Pro Ala Ile Ile Thr Gln Val Thr Asn Pro Lys Glu Asp 
1               5                   10                  15      


Glu Gly Arg Leu Pro Gly Ala Gly Glu Lys Ala Ser Gln Cys Asn Val 
            20                  25                  30          


Ser Leu Lys Lys Gln Arg Ser Arg Ser Ile Leu Ser Ser Phe Phe Cys 
        35                  40                  45              


Cys Phe Arg Asp Tyr Asn Val Glu Ala Pro Pro Pro Ser Ser Pro Ser 
    50                  55                  60                  


Val Leu Pro Pro Leu Val Glu Glu Asn Gly Gly Leu Gln Lys Gly Asp 
65                  70                  75                  80  


Gln Arg Gln Val Ile Pro Ile Pro Ser Pro Pro Ala Lys Tyr Leu Leu 
                85                  90                  95      


Pro Glu Val Thr Val Leu Asp Tyr Gly Lys Lys Cys Val Val Ile Asp 
            100                 105                 110         


Leu Asp Glu Thr Leu Val His Ser Ser Phe Lys Pro Ile Ser Asn Ala 
        115                 120                 125             


Asp Phe Ile Val Pro Val Glu Ile Asp Gly Thr Ile His Gln Val Tyr 
    130                 135                 140                 


Val Leu Lys Arg Pro His Val Asp Glu Phe Leu Gln Arg Met Gly Gln 
145                 150                 155                 160 


Leu Phe Glu Cys Val Leu Phe Thr Ala Ser Leu Ala Lys Tyr Ala Asp 
                165                 170                 175     


Pro Val Ala Asp Leu Leu Asp Arg Trp Gly Val Phe Arg Ala Arg Leu 
            180                 185                 190         


Phe Arg Glu Ser Cys Val Phe His Arg Gly Asn Tyr Val Lys Asp Leu 
        195                 200                 205             


Ser Arg Leu Gly Arg Glu Leu Ser Lys Val Ile Ile Val Asp Asn Ser 
    210                 215                 220                 


Pro Ala Ser Tyr Ile Phe His Pro Glu Asn Ala Val Pro Val Gln Ser 
225                 230                 235                 240 


Trp Phe Asp Asp Met Thr Asp Thr Glu Leu Leu Asp Leu Ile Pro Phe 
                245                 250                 255     


Phe Glu Gly Leu Ser Arg Glu Asp Asp Val Tyr Ser Met Leu His Arg 
            260                 265                 270         


Leu Cys Asn Arg 
        275     


<210>  3198
<211>  201
<212>  PRT
<213>  homo sapiens

<400>  3198

Met Ser Arg Arg Glu Gly Ser Leu Glu Asp Pro Gln Thr Asp Ser Ser 
1               5                   10                  15      


Val Ser Leu Leu Pro His Leu Glu Ala Lys Ile Arg Gln Thr His Ser 
            20                  25                  30          


Leu Ala His Leu Leu Thr Lys Tyr Ala Glu Gln Leu Leu Gln Glu Tyr 
        35                  40                  45              


Val Gln Leu Gln Gly Asp Pro Phe Gly Leu Pro Ser Phe Ser Pro Pro 
    50                  55                  60                  


Arg Leu Pro Val Ala Gly Leu Ser Ala Pro Ala Pro Ser His Ala Gly 
65                  70                  75                  80  


Leu Pro Val His Glu Arg Leu Arg Leu Asp Ala Ala Ala Leu Ala Ala 
                85                  90                  95      


Leu Pro Pro Leu Leu Asp Ala Val Cys Arg Arg Gln Ala Glu Leu Asn 
            100                 105                 110         


Pro Arg Ala Pro Arg Leu Leu Arg Arg Leu Glu Asp Ala Ala Arg Gln 
        115                 120                 125             


Ala Arg Ala Leu Gly Ala Ala Val Glu Ala Leu Leu Ala Ala Leu Gly 
    130                 135                 140                 


Ala Ala Asn Arg Gly Pro Arg Ala Glu Pro Pro Ala Ala Thr Ala Ser 
145                 150                 155                 160 


Ala Ala Ser Ala Thr Gly Val Phe Pro Ala Lys Val Leu Gly Leu Arg 
                165                 170                 175     


Val Cys Gly Leu Tyr Arg Glu Trp Leu Ser Arg Thr Glu Gly Asp Leu 
            180                 185                 190         


Gly Gln Leu Leu Pro Gly Gly Ser Ala 
        195                 200     


<210>  3199
<211>  200
<212>  PRT
<213>  homo sapiens

<400>  3199

Met Ser Arg Arg Glu Gly Ser Leu Asp Pro Gln Thr Asp Ser Ser Val 
1               5                   10                  15      


Ser Leu Leu Pro His Leu Glu Ala Lys Ile Arg Gln Thr His Ser Leu 
            20                  25                  30          


Ala His Leu Leu Thr Lys Tyr Ala Glu Gln Leu Leu Gln Glu Tyr Val 
        35                  40                  45              


Gln Leu Gln Gly Asp Pro Phe Gly Leu Pro Ser Phe Ser Pro Pro Arg 
    50                  55                  60                  


Leu Pro Val Ala Gly Leu Ser Ala Pro Ala Pro Ser His Ala Gly Leu 
65                  70                  75                  80  


Pro Val His Glu Arg Leu Arg Leu Asp Ala Ala Ala Leu Ala Ala Leu 
                85                  90                  95      


Pro Pro Leu Leu Asp Ala Val Cys Arg Arg Gln Ala Glu Leu Asn Pro 
            100                 105                 110         


Arg Ala Pro Arg Leu Leu Arg Arg Leu Glu Asp Ala Ala Arg Gln Ala 
        115                 120                 125             


Arg Ala Leu Gly Ala Ala Val Glu Ala Leu Leu Ala Ala Leu Gly Ala 
    130                 135                 140                 


Ala Asn Arg Gly Pro Arg Ala Glu Pro Pro Ala Ala Thr Ala Ser Ala 
145                 150                 155                 160 


Ala Ser Ala Thr Gly Val Phe Pro Ala Lys Val Leu Gly Leu Arg Val 
                165                 170                 175     


Cys Gly Leu Tyr Arg Glu Trp Leu Ser Arg Thr Glu Gly Asp Leu Gly 
            180                 185                 190         


Gln Leu Leu Pro Gly Gly Ser Ala 
        195                 200 


<210>  3200
<211>  500
<212>  PRT
<213>  homo sapiens

<400>  3200

Met Glu Thr Glu Ala Ile Asp Gly Tyr Ile Thr Cys Asp Asn Glu Leu 
1               5                   10                  15      


Ser Pro Glu Arg Glu His Ser Asn Met Ala Ile Asp Leu Thr Ser Ser 
            20                  25                  30          


Thr Pro Asn Gly Gln His Ala Ser Pro Ser His Met Thr Ser Thr Asn 
        35                  40                  45              


Ser Val Lys Leu Glu Met Gln Ser Asp Glu Glu Cys Asp Arg Lys Pro 
    50                  55                  60                  


Leu Ser Arg Glu Asp Glu Ile Arg Gly His Asp Glu Gly Ser Ser Leu 
65                  70                  75                  80  


Glu Glu Pro Leu Ile Glu Ser Ser Glu Val Ala Asp Asn Arg Lys Val 
                85                  90                  95      


Gln Glu Leu Gln Gly Glu Gly Gly Ile Arg Leu Pro Asn Gly Glu Arg 
            100                 105                 110         


Pro Phe His Cys Asn Gln Cys Gly Ala Ser Phe Thr Gln Lys Gly Asn 
        115                 120                 125             


Leu Leu Arg His Ile Lys Leu His Ser Gly Glu Lys Pro Phe Lys Cys 
    130                 135                 140                 


Pro Phe Cys Ser Tyr Ala Cys Arg Arg Arg Asp Ala Leu Thr Gly His 
145                 150                 155                 160 


Leu Arg Thr His Ser Val Gly Lys Pro His Lys Cys Asn Tyr Cys Gly 
                165                 170                 175     


Arg Ser Tyr Lys Gln Arg Ser Ser Leu Glu Glu His Lys Glu Arg Cys 
            180                 185                 190         


His Asn Tyr Leu Gln Asn Val Ser Met Glu Ala Ala Gly Gln Val Met 
        195                 200                 205             


Ser His His Val Pro Pro Met Glu Asp Cys Lys Glu Gln Glu Pro Ile 
    210                 215                 220                 


Met Asp Asn Asn Ile Ser Leu Val Pro Phe Glu Arg Pro Ala Val Ile 
225                 230                 235                 240 


Glu Lys Leu Thr Gly Asn Met Gly Lys Arg Lys Ser Ser Thr Pro Gln 
                245                 250                 255     


Lys Phe Val Gly Glu Lys Leu Met Arg Phe Ser Tyr Pro Asp Ile His 
            260                 265                 270         


Phe Asp Met Asn Leu Thr Tyr Glu Lys Glu Ala Glu Leu Met Gln Ser 
        275                 280                 285             


His Met Met Asp Gln Ala Ile Asn Asn Ala Ile Thr Tyr Leu Gly Ala 
    290                 295                 300                 


Glu Ala Leu His Pro Leu Met Gln His Pro Pro Ser Thr Ile Ala Glu 
305                 310                 315                 320 


Val Ala Pro Val Ile Ser Ser Ala Tyr Ser Gln Val Tyr His Pro Asn 
                325                 330                 335     


Arg Ile Glu Arg Pro Ile Ser Arg Glu Thr Ala Asp Ser His Glu Asn 
            340                 345                 350         


Asn Met Asp Gly Pro Ile Ser Leu Ile Arg Pro Lys Ser Arg Pro Gln 
        355                 360                 365             


Glu Arg Glu Ala Ser Pro Ser Asn Ser Cys Leu Asp Ser Thr Asp Ser 
    370                 375                 380                 


Glu Ser Ser His Asp Asp His Gln Ser Tyr Gln Gly His Pro Ala Leu 
385                 390                 395                 400 


Asn Pro Lys Arg Lys Gln Ser Pro Ala Tyr Met Lys Glu Asp Val Lys 
                405                 410                 415     


Ala Leu Asp Thr Thr Lys Ala Pro Lys Gly Ser Leu Lys Asp Ile Tyr 
            420                 425                 430         


Lys Val Phe Asn Gly Glu Gly Glu Gln Ile Arg Ala Phe Lys Cys Glu 
        435                 440                 445             


His Cys Arg Val Leu Phe Leu Asp His Val Met Tyr Thr Ile His Met 
    450                 455                 460                 


Gly Cys His Gly Tyr Arg Asp Pro Leu Glu Cys Asn Ile Cys Gly Tyr 
465                 470                 475                 480 


Arg Ser Gln Asp Arg Tyr Glu Phe Ser Ser His Ile Val Arg Gly Glu 
                485                 490                 495     


His Thr Phe His 
            500 


<210>  3201
<211>  938
<212>  PRT
<213>  homo sapiens

<400>  3201

Met Leu Trp Pro Arg Leu Ala Ala Ala Glu Trp Ala Ala Leu Ala Trp 
1               5                   10                  15      


Glu Leu Leu Gly Ala Ser Val Leu Leu Ile Ala Val Arg Trp Leu Val 
            20                  25                  30          


Arg Arg Leu Gly Pro Arg Pro Gly Gly Leu Gly Arg Ser Gly Thr Pro 
        35                  40                  45              


Val Pro Pro Pro Ser Ala Ala Ala Ala Pro Ala Ser Gly Glu Met Thr 
    50                  55                  60                  


Met Asp Ala Leu Leu Ala Arg Leu Lys Leu Leu Asn Pro Asp Asp Leu 
65                  70                  75                  80  


Arg Glu Glu Ile Val Lys Ala Gly Leu Lys Cys Gly Pro Ile Thr Ser 
                85                  90                  95      


Thr Thr Arg Phe Ile Phe Glu Lys Lys Leu Ala Gln Ala Leu Leu Glu 
            100                 105                 110         


Gln Gly Gly Arg Leu Ser Ser Phe Tyr His His Glu Ala Gly Val Thr 
        115                 120                 125             


Ala Leu Ser Gln Asp Pro Gln Arg Ile Leu Lys Pro Ala Glu Gly Asn 
    130                 135                 140                 


Pro Thr Asp Gln Ala Gly Phe Ser Glu Asp Arg Asp Phe Gly Tyr Ser 
145                 150                 155                 160 


Val Gly Leu Asn Pro Pro Glu Glu Glu Ala Val Thr Ser Lys Thr Cys 
                165                 170                 175     


Ser Val Pro Pro Ser Asp Thr Asp Thr Tyr Arg Ala Gly Ala Thr Ala 
            180                 185                 190         


Ser Lys Glu Pro Pro Leu Tyr Tyr Gly Val Cys Pro Val Tyr Glu Asp 
        195                 200                 205             


Val Pro Ala Arg Asn Glu Arg Ile Tyr Val Tyr Glu Asn Lys Lys Glu 
    210                 215                 220                 


Ala Leu Gln Ala Val Lys Met Ile Lys Gly Ser Arg Phe Lys Ala Phe 
225                 230                 235                 240 


Ser Thr Arg Glu Asp Ala Glu Lys Phe Ala Arg Gly Ile Cys Asp Tyr 
                245                 250                 255     


Phe Pro Ser Pro Ser Lys Thr Ser Leu Pro Leu Ser Pro Val Lys Thr 
            260                 265                 270         


Ala Pro Leu Phe Ser Asn Asp Arg Leu Lys Asp Gly Leu Cys Leu Ser 
        275                 280                 285             


Glu Ser Glu Thr Val Asn Lys Glu Arg Ala Asn Ser Tyr Lys Asn Pro 
    290                 295                 300                 


Arg Thr Gln Asp Leu Thr Ala Lys Leu Arg Lys Ala Val Glu Lys Gly 
305                 310                 315                 320 


Glu Glu Asp Thr Phe Ser Asp Leu Ile Trp Ser Asn Pro Arg Tyr Leu 
                325                 330                 335     


Ile Gly Ser Gly Asp Asn Pro Thr Ile Val Gln Glu Gly Cys Arg Tyr 
            340                 345                 350         


Asn Val Met His Val Ala Ala Lys Glu Asn Gln Ala Ser Ile Cys Gln 
        355                 360                 365             


Leu Thr Leu Asp Val Leu Glu Asn Pro Asp Phe Met Arg Leu Met Tyr 
    370                 375                 380                 


Pro Asp Asp Asp Glu Ala Met Leu Gln Lys Arg Ile Arg Tyr Val Val 
385                 390                 395                 400 


Asp Leu Tyr Leu Asn Thr Pro Asp Lys Met Gly Tyr Asp Thr Pro Leu 
                405                 410                 415     


His Phe Ala Cys Lys Phe Gly Asn Ala Asp Val Val Asn Val Leu Ser 
            420                 425                 430         


Ser His His Leu Ile Val Lys Asn Ser Arg Asn Lys Tyr Asp Lys Thr 
        435                 440                 445             


Pro Glu Asp Val Ile Cys Glu Arg Ser Lys Asn Lys Ser Val Glu Leu 
    450                 455                 460                 


Lys Glu Arg Ile Arg Glu Tyr Leu Lys Gly His Tyr Tyr Val Pro Leu 
465                 470                 475                 480 


Leu Arg Ala Glu Glu Thr Ser Ser Pro Val Ile Gly Glu Leu Trp Ser 
                485                 490                 495     


Pro Asp Gln Thr Ala Glu Ala Ser His Val Ser Arg Tyr Gly Gly Ser 
            500                 505                 510         


Pro Arg Asp Pro Val Leu Thr Leu Arg Ala Phe Ala Gly Pro Leu Ser 
        515                 520                 525             


Pro Ala Lys Ala Glu Asp Phe Arg Lys Leu Trp Lys Thr Pro Pro Arg 
    530                 535                 540                 


Glu Lys Ala Gly Phe Leu His His Val Lys Lys Ser Asp Pro Glu Arg 
545                 550                 555                 560 


Gly Phe Glu Arg Val Gly Arg Glu Leu Ala His Glu Leu Gly Tyr Pro 
                565                 570                 575     


Trp Val Glu Tyr Trp Glu Phe Leu Gly Cys Phe Val Asp Leu Ser Ser 
            580                 585                 590         


Gln Glu Gly Leu Gln Arg Leu Glu Glu Tyr Leu Thr Gln Gln Glu Ile 
        595                 600                 605             


Gly Lys Lys Ala Gln Gln Glu Thr Gly Glu Arg Glu Ala Ser Cys Arg 
    610                 615                 620                 


Asp Lys Ala Thr Thr Ser Gly Ser Asn Ser Ile Ser Val Arg Ala Phe 
625                 630                 635                 640 


Leu Asp Glu Asp Asp Met Ser Leu Glu Glu Ile Lys Asn Arg Gln Asn 
                645                 650                 655     


Ala Ala Arg Asn Asn Ser Pro Pro Thr Val Gly Ala Phe Gly His Thr 
            660                 665                 670         


Arg Cys Ser Ala Phe Pro Leu Glu Gln Glu Ala Asp Leu Ile Glu Ala 
        675                 680                 685             


Ala Glu Pro Gly Gly Pro His Ser Ser Arg Asn Gly Leu Cys His Pro 
    690                 695                 700                 


Leu Asn His Ser Arg Thr Leu Ala Gly Lys Arg Pro Lys Ala Pro Arg 
705                 710                 715                 720 


Gly Glu Glu Ala His Leu Pro Pro Val Ser Asp Leu Thr Val Glu Phe 
                725                 730                 735     


Asp Lys Leu Asn Leu Gln Asn Ile Gly Arg Ser Val Ser Lys Thr Pro 
            740                 745                 750         


Asp Glu Ser Thr Lys Thr Lys Asp Gln Ile Leu Thr Ser Arg Ile Asn 
        755                 760                 765             


Ala Val Glu Arg Asp Leu Leu Glu Pro Ser Pro Ala Asp Gln Leu Gly 
    770                 775                 780                 


Asn Gly His Arg Arg Thr Glu Ser Glu Met Ser Ala Arg Ile Ala Lys 
785                 790                 795                 800 


Met Ser Leu Ser Pro Ser Ser Pro Arg His Glu Asp Gln Leu Glu Val 
                805                 810                 815     


Thr Arg Glu Pro Ala Arg Arg Leu Phe Leu Phe Gly Glu Glu Pro Ser 
            820                 825                 830         


Lys Leu Asp Gln Asp Val Leu Ala Ala Leu Glu Cys Ala Asp Val Asp 
        835                 840                 845             


Pro His Gln Phe Pro Ala Val His Arg Trp Lys Ser Ala Val Leu Cys 
    850                 855                 860                 


Tyr Ser Pro Ser Asp Arg Gln Ser Trp Pro Ser Pro Ala Val Lys Gly 
865                 870                 875                 880 


Arg Phe Lys Ser Gln Leu Pro Asp Leu Ser Gly Pro His Ser Tyr Ser 
                885                 890                 895     


Pro Gly Arg Asn Ser Val Ala Gly Ser Asn Pro Ala Lys Pro Gly Leu 
            900                 905                 910         


Gly Ser Pro Gly Arg Tyr Ser Pro Val His Gly Ser Gln Leu Arg Arg 
        915                 920                 925             


Met Ala Arg Leu Ala Glu Leu Ala Ala Leu 
    930                 935             


<210>  3202
<211>  241
<212>  PRT
<213>  homo sapiens

<400>  3202

Met Pro Pro Leu Leu Pro Leu Arg Leu Cys Arg Leu Trp Pro Arg Asn 
1               5                   10                  15      


Pro Pro Ser Arg Leu Leu Gly Ala Ala Ala Gly Gln Arg Ser Arg Pro 
            20                  25                  30          


Ser Thr Tyr Tyr Glu Leu Leu Gly Val His Pro Gly Ala Ser Thr Glu 
        35                  40                  45              


Glu Val Lys Arg Ala Phe Phe Ser Lys Ser Lys Glu Leu His Pro Asp 
    50                  55                  60                  


Arg Asp Pro Gly Asn Pro Ser Leu His Ser Arg Phe Val Glu Leu Ser 
65                  70                  75                  80  


Glu Ala Tyr Arg Val Leu Ser Arg Glu Gln Ser Arg Arg Ser Tyr Asp 
                85                  90                  95      


Asp Gln Leu Arg Ser Gly Ser Pro Pro Lys Ser Pro Arg Thr Thr Val 
            100                 105                 110         


His Asp Lys Ser Ala His Gln Thr His Ser Ser Trp Thr Pro Pro Asn 
        115                 120                 125             


Ala Gln Tyr Trp Ser Gln Phe His Ser Val Arg Pro Gln Gly Pro Gln 
    130                 135                 140                 


Leu Arg Gln Gln Gln His Lys Gln Asn Lys Gln Val Leu Gly Tyr Cys 
145                 150                 155                 160 


Leu Leu Leu Met Leu Ala Gly Met Gly Leu His Tyr Ile Ala Phe Arg 
                165                 170                 175     


Lys Val Lys Gln Met His Leu Asn Phe Met Asp Glu Lys Asp Arg Ile 
            180                 185                 190         


Ile Thr Ala Phe Tyr Asn Glu Ala Arg Ala Arg Ala Arg Ala Asn Arg 
        195                 200                 205             


Gly Ile Leu Gln Gln Glu Arg Gln Arg Leu Gly Gln Arg Gln Pro Pro 
    210                 215                 220                 


Pro Ser Glu Pro Thr Gln Gly Pro Glu Ile Val Pro Arg Gly Ala Gly 
225                 230                 235                 240 


Pro 
    


<210>  3203
<211>  277
<212>  PRT
<213>  homo sapiens

<400>  3203

Met Gly Leu Leu Glu Cys Cys Ala Arg Cys Leu Val Gly Ala Pro Phe 
1               5                   10                  15      


Ala Ser Leu Val Ala Thr Gly Leu Cys Phe Phe Gly Val Ala Leu Phe 
            20                  25                  30          


Cys Gly Cys Gly His Glu Ala Leu Thr Gly Thr Glu Lys Leu Ile Glu 
        35                  40                  45              


Thr Tyr Phe Ser Lys Asn Tyr Gln Asp Tyr Glu Tyr Leu Ile Asn Val 
    50                  55                  60                  


Ile His Ala Phe Gln Tyr Val Ile Tyr Gly Thr Ala Ser Phe Phe Phe 
65                  70                  75                  80  


Leu Tyr Gly Ala Leu Leu Leu Ala Glu Gly Phe Tyr Thr Thr Gly Ala 
                85                  90                  95      


Val Arg Gln Ile Phe Gly Asp Tyr Lys Thr Thr Ile Cys Gly Lys Gly 
            100                 105                 110         


Leu Ser Ala Thr Val Thr Gly Gly Gln Lys Gly Arg Gly Ser Arg Gly 
        115                 120                 125             


Gln His Gln Ala His Ser Leu Glu Arg Val Cys His Cys Leu Gly Lys 
    130                 135                 140                 


Trp Leu Gly His Pro Asp Lys Phe Val Gly Ile Thr Tyr Ala Leu Thr 
145                 150                 155                 160 


Val Val Trp Leu Leu Val Phe Ala Cys Ser Ala Val Pro Val Tyr Ile 
                165                 170                 175     


Tyr Phe Asn Thr Trp Thr Thr Cys Gln Ser Ile Ala Phe Pro Ser Lys 
            180                 185                 190         


Thr Ser Ala Ser Ile Gly Ser Leu Cys Ala Asp Ala Arg Met Tyr Gly 
        195                 200                 205             


Val Leu Pro Trp Asn Ala Phe Pro Gly Lys Val Cys Gly Ser Asn Leu 
    210                 215                 220                 


Leu Ser Ile Cys Lys Thr Ala Glu Phe Gln Met Thr Phe His Leu Phe 
225                 230                 235                 240 


Ile Ala Ala Phe Val Gly Ala Ala Ala Thr Leu Val Ser Leu Leu Thr 
                245                 250                 255     


Phe Met Ile Ala Ala Thr Tyr Asn Phe Ala Val Leu Lys Leu Met Gly 
            260                 265                 270         


Arg Gly Thr Lys Phe 
        275         


<210>  3204
<211>  319
<212>  PRT
<213>  homo sapiens

<400>  3204

Met Met Val Leu Lys Val Glu Glu Leu Val Thr Gly Lys Lys Asn Gly 
1               5                   10                  15      


Asn Gly Glu Ala Gly Glu Phe Leu Pro Glu Asp Phe Arg Asp Gly Glu 
            20                  25                  30          


Tyr Glu Ala Ala Val Thr Leu Glu Lys Gln Glu Asp Leu Lys Thr Leu 
        35                  40                  45              


Leu Ala His Pro Val Thr Leu Gly Glu Gln Gln Trp Lys Ser Glu Lys 
    50                  55                  60                  


Gln Arg Glu Ala Glu Leu Lys Lys Lys Lys Leu Glu Gln Arg Ser Lys 
65                  70                  75                  80  


Leu Glu Asn Leu Glu Asp Leu Glu Ile Ile Ile Gln Leu Lys Lys Arg 
                85                  90                  95      


Lys Lys Tyr Arg Lys Thr Lys Val Pro Val Val Lys Glu Pro Glu Pro 
            100                 105                 110         


Glu Ile Ile Thr Glu Pro Val Asp Val Pro Thr Phe Leu Lys Ala Ala 
        115                 120                 125             


Leu Glu Asn Lys Leu Pro Val Val Glu Lys Phe Leu Ser Asp Lys Asn 
    130                 135                 140                 


Asn Pro Asp Val Cys Asp Glu Tyr Lys Arg Thr Ala Leu His Arg Ala 
145                 150                 155                 160 


Cys Leu Glu Gly His Leu Ala Ile Val Glu Lys Leu Met Glu Ala Gly 
                165                 170                 175     


Ala Gln Ile Glu Phe Arg Asp Met Leu Glu Ser Thr Ala Ile His Trp 
            180                 185                 190         


Ala Ser Arg Gly Gly Asn Leu Asp Val Leu Lys Leu Leu Leu Asn Lys 
        195                 200                 205             


Gly Ala Lys Ile Ser Ala Arg Asp Lys Leu Leu Ser Thr Ala Leu His 
    210                 215                 220                 


Val Ala Val Arg Thr Gly His Tyr Glu Cys Ala Glu His Leu Ile Ala 
225                 230                 235                 240 


Cys Glu Ala Asp Leu Asn Ala Lys Asp Arg Glu Gly Asp Thr Pro Leu 
                245                 250                 255     


His Asp Ala Val Arg Leu Asn Arg Tyr Lys Met Ile Arg Leu Leu Ile 
            260                 265                 270         


Met Tyr Gly Ala Asp Leu Asn Ile Lys Asn Cys Ala Gly Lys Thr Pro 
        275                 280                 285             


Met Asp Leu Val Leu His Trp Gln Asn Gly Thr Lys Ala Ile Phe Asp 
    290                 295                 300                 


Ser Leu Arg Glu Asn Ser Tyr Lys Thr Ser Arg Ile Ala Thr Phe 
305                 310                 315                 


<210>  3205
<211>  661
<212>  PRT
<213>  homo sapiens

<400>  3205

Met Asn Thr Gly Arg Asp Ser Gln Ser Pro Asp Ser Ala Trp Arg Ser 
1               5                   10                  15      


Tyr Asn Asp Gly Asn Gln Glu Thr Leu Asn Gly Asp Ala Thr Tyr Ser 
            20                  25                  30          


Ser Leu Ala Ala Lys Gly Phe Arg Ser Val Arg Pro Asn Leu Gln Asp 
        35                  40                  45              


Lys Arg Ser Pro Thr Gln Ser Gln Ile Thr Val Asn Gly Asn Ser Gly 
    50                  55                  60                  


Gly Ala Val Ser Pro Met Ser Tyr Tyr Gln Arg Pro Phe Ser Pro Ser 
65                  70                  75                  80  


Ala Tyr Ser Leu Pro Ala Ser Leu Asn Ser Ser Ile Val Met Gln His 
                85                  90                  95      


Gly Thr Ser Leu Asp Ser Thr Asp Thr Tyr Pro Gln His Ala Gln Ser 
            100                 105                 110         


Leu Asp Gly Thr Thr Ser Ser Ser Ile Pro Leu Tyr Arg Ser Ser Glu 
        115                 120                 125             


Glu Glu Lys Arg Val Thr Val Ile Lys Ala Pro His Tyr Pro Gly Ile 
    130                 135                 140                 


Gly Pro Val Asp Glu Ser Gly Ile Pro Thr Ala Ile Arg Thr Thr Val 
145                 150                 155                 160 


Asp Arg Pro Lys Asp Trp Tyr Lys Thr Met Phe Lys Gln Ile His Met 
                165                 170                 175     


Val His Lys Pro Asp Asp Asp Thr Asp Met Tyr Asn Thr Pro Tyr Thr 
            180                 185                 190         


Tyr Asn Ala Gly Leu Tyr Asn Pro Pro Tyr Ser Ala Gln Ser His Pro 
        195                 200                 205             


Ala Ala Lys Thr Gln Thr Tyr Arg Pro Leu Ser Lys Ser His Ser Asp 
    210                 215                 220                 


Asn Ser Pro Asn Ala Phe Lys Asp Ala Ser Ser Pro Val Pro Pro Pro 
225                 230                 235                 240 


His Val Pro Pro Pro Val Pro Pro Leu Arg Pro Arg Asp Arg Ser Ser 
                245                 250                 255     


Thr Glu Lys His Asp Trp Asp Pro Pro Asp Arg Lys Val Asp Thr Arg 
            260                 265                 270         


Lys Phe Arg Ser Glu Pro Arg Ser Ile Phe Glu Tyr Glu Pro Gly Lys 
        275                 280                 285             


Ser Ser Ile Leu Gln His Glu Arg Pro Pro Pro Lys Lys Pro Leu Asp 
    290                 295                 300                 


Tyr Val Gln Asp His Ser Ser Gly Val Phe Asn Glu Ala Ser Leu Tyr 
305                 310                 315                 320 


Gln Ser Ser Ile Asp Arg Ser Leu Glu Arg Pro Met Ser Ser Ala Ser 
                325                 330                 335     


Met Ala Ser Asp Phe Arg Lys Arg Arg Lys Ser Glu Pro Ala Val Gly 
            340                 345                 350         


Pro Pro Arg Gly Leu Gly Asp Gln Ser Ala Ser Arg Thr Ser Pro Gly 
        355                 360                 365             


Arg Val Asp Leu Pro Gly Ser Ser Thr Thr Leu Thr Lys Ser Phe Thr 
    370                 375                 380                 


Ser Ser Ser Pro Ser Ser Pro Ser Arg Ala Lys Asp Arg Glu Ser Pro 
385                 390                 395                 400 


Arg Ser Tyr Ser Ser Thr Leu Thr Asp Met Gly Arg Ser Ala Pro Arg 
                405                 410                 415     


Glu Arg Arg Gly Thr Pro Glu Lys Glu Lys Leu Pro Ala Lys Ala Val 
            420                 425                 430         


Tyr Asp Phe Lys Ala Gln Thr Ser Lys Glu Leu Ser Phe Lys Lys Gly 
        435                 440                 445             


Asp Thr Val Tyr Ile Leu Arg Lys Ile Asp Gln Asn Trp Tyr Glu Gly 
    450                 455                 460                 


Glu His His Gly Arg Val Gly Ile Phe Pro Ile Ser Tyr Val Glu Lys 
465                 470                 475                 480 


Leu Thr Pro Pro Glu Lys Ala Gln Pro Ala Arg Pro Pro Pro Pro Ala 
                485                 490                 495     


Gln Pro Gly Glu Ile Gly Glu Ala Ile Ala Lys Tyr Asn Phe Asn Ala 
            500                 505                 510         


Asp Thr Asn Val Glu Leu Ser Leu Arg Lys Gly Asp Arg Val Ile Leu 
        515                 520                 525             


Leu Lys Arg Val Asp Gln Asn Trp Tyr Glu Gly Lys Ile Pro Gly Thr 
    530                 535                 540                 


Asn Arg Gln Gly Ile Phe Pro Val Ser Tyr Val Glu Val Val Lys Lys 
545                 550                 555                 560 


Asn Thr Lys Gly Ala Glu Asp Tyr Pro Asp Pro Pro Ile Pro His Ser 
                565                 570                 575     


Tyr Ser Ser Asp Arg Ile His Ser Leu Ser Ser Asn Lys Pro Gln Arg 
            580                 585                 590         


Pro Val Phe Thr His Glu Asn Ile Gln Gly Gly Gly Glu Pro Phe Gln 
        595                 600                 605             


Ala Leu Tyr Asn Tyr Thr Pro Arg Asn Glu Asp Glu Leu Glu Leu Arg 
    610                 615                 620                 


Glu Ser Asp Val Ile Asp Val Met Glu Lys Cys Asp Asp Gly Trp Phe 
625                 630                 635                 640 


Val Gly Thr Ser Arg Arg Thr Lys Phe Phe Gly Thr Phe Pro Gly Asn 
                645                 650                 655     


Tyr Val Lys Arg Leu 
            660     


<210>  3206
<211>  400
<212>  PRT
<213>  homo sapiens

<400>  3206

Met Glu Asp Gly Val Tyr Glu Pro Pro Asp Leu Thr Pro Glu Glu Arg 
1               5                   10                  15      


Met Glu Leu Glu Asn Ile Arg Arg Arg Lys Gln Glu Leu Leu Val Glu 
            20                  25                  30          


Ile Gln Arg Leu Arg Glu Glu Leu Ser Glu Ala Met Ser Glu Val Glu 
        35                  40                  45              


Gly Leu Glu Ala Asn Glu Gly Ser Lys Thr Leu Gln Arg Asn Arg Lys 
    50                  55                  60                  


Met Ala Met Gly Arg Lys Lys Phe Asn Met Asp Pro Lys Lys Gly Ile 
65                  70                  75                  80  


Gln Phe Leu Val Glu Asn Glu Leu Leu Gln Asn Thr Pro Glu Glu Ile 
                85                  90                  95      


Ala Arg Phe Leu Tyr Lys Gly Glu Gly Leu Asn Lys Thr Ala Ile Gly 
            100                 105                 110         


Asp Tyr Leu Gly Glu Arg Glu Glu Leu Asn Leu Ala Val Leu His Ala 
        115                 120                 125             


Phe Val Asp Leu His Glu Phe Thr Asp Leu Asn Leu Val Gln Ala Leu 
    130                 135                 140                 


Arg Gln Phe Leu Trp Ser Phe Arg Leu Pro Gly Glu Ala Gln Lys Ile 
145                 150                 155                 160 


Asp Arg Met Met Glu Ala Phe Ala Gln Arg Tyr Cys Leu Cys Asn Pro 
                165                 170                 175     


Gly Val Phe Gln Ser Thr Asp Thr Cys Tyr Val Leu Ser Phe Ala Val 
            180                 185                 190         


Ile Met Leu Asn Thr Ser Leu His Asn Pro Asn Val Arg Asp Lys Pro 
        195                 200                 205             


Gly Leu Glu Arg Phe Val Ala Met Asn Arg Gly Ile Asn Glu Gly Gly 
    210                 215                 220                 


Asp Leu Pro Glu Glu Leu Leu Arg Asn Leu Tyr Asp Ser Ile Arg Asn 
225                 230                 235                 240 


Glu Pro Phe Lys Ile Pro Glu Asp Asp Gly Asn Asp Leu Thr His Thr 
                245                 250                 255     


Phe Phe Asn Pro Asp Arg Glu Gly Trp Leu Leu Lys Leu Gly Gly Gly 
            260                 265                 270         


Arg Val Lys Thr Trp Lys Arg Arg Trp Phe Ile Leu Thr Asp Asn Cys 
        275                 280                 285             


Leu Tyr Tyr Phe Glu Tyr Thr Thr Asp Lys Glu Pro Arg Gly Ile Ile 
    290                 295                 300                 


Pro Leu Glu Asn Leu Ser Ile Arg Glu Val Asp Asp Pro Arg Lys Pro 
305                 310                 315                 320 


Asn Cys Phe Glu Leu Tyr Ile Pro Asn Asn Lys Gly Gln Leu Ile Lys 
                325                 330                 335     


Ala Cys Lys Thr Glu Ala Asp Gly Arg Val Val Glu Gly Asn His Met 
            340                 345                 350         


Val Tyr Arg Ile Ser Ala Pro Thr Gln Glu Glu Lys Asp Glu Trp Ile 
        355                 360                 365             


Lys Ser Ile Gln Ala Ala Val Ser Val Asp Pro Phe Tyr Glu Met Leu 
    370                 375                 380                 


Ala Ala Arg Lys Lys Arg Ile Ser Val Lys Lys Lys Gln Glu Gln Pro 
385                 390                 395                 400 


<210>  3207
<211>  1087
<212>  PRT
<213>  homo sapiens

<400>  3207

Met Thr Thr Glu Ser Gly Ser Asp Ser Glu Ser Lys Pro Asp Gln Glu 
1               5                   10                  15      


Ala Glu Pro Gln Glu Ala Ala Gly Ala Gln Gly Arg Ala Gly Ala Pro 
            20                  25                  30          


Val Pro Glu Pro Pro Lys Glu Glu Gln Gln Gln Ala Leu Glu Gln Phe 
        35                  40                  45              


Ala Ala Ala Ala Ala His Ser Thr Pro Val Arg Arg Glu Val Thr Asp 
    50                  55                  60                  


Lys Glu Gln Glu Phe Ala Ala Arg Ala Ala Lys Gln Leu Glu Tyr Gln 
65                  70                  75                  80  


Gln Leu Glu Asp Asp Lys Leu Ser Gln Lys Ser Ser Ser Ser Lys Leu 
                85                  90                  95      


Ser Arg Ser Pro Leu Lys Ile Val Lys Lys Pro Lys Ser Met Gln Cys 
            100                 105                 110         


Lys Val Ile Leu Leu Asp Gly Ser Glu Tyr Thr Cys Asp Val Glu Lys 
        115                 120                 125             


Arg Ser Arg Gly Gln Val Leu Phe Asp Lys Val Cys Glu His Leu Asn 
    130                 135                 140                 


Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Tyr Arg Asp Ala Glu Asn 
145                 150                 155                 160 


Gln Lys Asn Trp Leu Asp Pro Ala Lys Glu Ile Lys Lys Gln Val Arg 
                165                 170                 175     


Ser Gly Ala Trp His Phe Ser Phe Asn Val Lys Phe Tyr Pro Pro Asp 
            180                 185                 190         


Pro Ala Gln Leu Ser Glu Asp Ile Thr Arg Tyr Tyr Leu Cys Leu Gln 
        195                 200                 205             


Leu Arg Asp Asp Ile Val Ser Gly Arg Leu Pro Cys Ser Phe Val Thr 
    210                 215                 220                 


Leu Ala Leu Leu Gly Ser Tyr Thr Val Gln Ser Glu Leu Gly Asp Tyr 
225                 230                 235                 240 


Asp Pro Asp Glu Cys Gly Ser Asp Tyr Ile Ser Glu Phe Arg Phe Ala 
                245                 250                 255     


Pro Asn His Thr Lys Glu Leu Glu Asp Lys Val Ile Glu Leu His Lys 
            260                 265                 270         


Ser His Arg Gly Met Thr Pro Ala Glu Ala Glu Met His Phe Leu Glu 
        275                 280                 285             


Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His His Ala Lys 
    290                 295                 300                 


Asp Ser Glu Gly Val Glu Ile Met Leu Gly Val Cys Ala Ser Gly Leu 
305                 310                 315                 320 


Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg Phe Ala Trp Pro Lys 
                325                 330                 335     


Val Leu Lys Ile Ser Tyr Lys Arg Asn Asn Phe Tyr Ile Lys Ile Arg 
            340                 345                 350         


Pro Gly Glu Phe Glu Gln Phe Glu Ser Thr Ile Gly Phe Lys Leu Pro 
        355                 360                 365             


Asn His Arg Ala Ala Lys Arg Leu Trp Lys Val Cys Val Glu His His 
    370                 375                 380                 


Thr Phe Phe Arg Leu Leu Leu Pro Glu Ala Pro Pro Lys Lys Phe Leu 
385                 390                 395                 400 


Thr Leu Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr Gln Ala Gln Thr 
                405                 410                 415     


Arg Arg Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro Tyr Phe Glu Arg 
            420                 425                 430         


Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser Leu Asp Gly Glu Val 
        435                 440                 445             


Gly Thr Gly Gln Tyr Ala Thr Thr Lys Gly Ile Ser Gln Thr Asn Leu 
    450                 455                 460                 


Ile Thr Thr Val Thr Pro Glu Lys Lys Ala Glu Glu Glu Arg Asp Glu 
465                 470                 475                 480 


Glu Glu Asp Lys Arg Arg Lys Gly Glu Glu Val Thr Pro Ile Ser Ala 
                485                 490                 495     


Ile Arg His Glu Gly Lys Ser Pro Gly Leu Gly Thr Asp Ser Cys Pro 
            500                 505                 510         


Leu Ser Pro Pro Ser Thr His Cys Ala Pro Thr Ser Pro Thr Glu Leu 
        515                 520                 525             


Arg Arg Arg Cys Lys Glu Asn Asp Cys Lys Leu Pro Gly Tyr Glu Pro 
    530                 535                 540                 


Ser Arg Ala Glu His Leu Pro Gly Glu Pro Ala Leu Asp Ser Asp Gly 
545                 550                 555                 560 


Pro Gly Arg Pro Tyr Leu Gly Asp Gln Asp Val Ala Phe Ser Tyr Arg 
                565                 570                 575     


Gln Gln Thr Gly Lys Gly Thr Thr Leu Phe Ser Phe Ser Leu Gln Leu 
            580                 585                 590         


Pro Glu Ser Phe Pro Ser Leu Leu Asp Asp Asp Gly Tyr Leu Ser Phe 
        595                 600                 605             


Pro Asn Leu Ser Glu Thr Asn Leu Leu Pro Gln Ser Leu Gln His Tyr 
    610                 615                 620                 


Leu Pro Ile Arg Ser Pro Ser Leu Val Pro Cys Phe Leu Phe Ile Phe 
625                 630                 635                 640 


Phe Phe Leu Leu Ser Ala Ser Phe Ser Val Pro Tyr Ala Leu Thr Leu 
                645                 650                 655     


Ser Phe Pro Leu Ala Leu Cys Leu Cys Tyr Leu Glu Pro Lys Ala Ala 
            660                 665                 670         


Ser Leu Ser Ala Ser Leu Asp Asn Asp Pro Ser Asp Ser Ser Glu Glu 
        675                 680                 685             


Glu Thr Asp Ser Glu Arg Thr Asp Thr Ala Ala Asp Gly Glu Thr Thr 
    690                 695                 700                 


Ala Thr Glu Ser Asp Gln Glu Glu Asp Ala Glu Leu Lys Ala Gln Glu 
705                 710                 715                 720 


Leu Glu Lys Thr Gln Asp Asp Leu Met Lys His Gln Thr Asn Ile Ser 
                725                 730                 735     


Glu Leu Lys Arg Thr Phe Leu Glu Thr Ser Thr Asp Thr Ala Val Thr 
            740                 745                 750         


Asn Glu Trp Glu Lys Arg Leu Ser Thr Ser Pro Val Arg Leu Ala Ala 
        755                 760                 765             


Arg Gln Glu Asp Ala Pro Met Ile Glu Pro Leu Val Pro Glu Glu Thr 
    770                 775                 780                 


Lys Gln Ser Ser Gly Glu Lys Leu Met Asp Gly Ser Glu Ile Phe Ser 
785                 790                 795                 800 


Leu Leu Glu Ser Ala Arg Lys Pro Thr Glu Phe Ile Gly Gly Val Thr 
                805                 810                 815     


Ser Thr Ser Gln Ser Trp Val Gln Lys Met Glu Thr Lys Thr Glu Ser 
            820                 825                 830         


Ser Gly Ile Glu Thr Glu Pro Thr Val His His Leu Pro Leu Ser Thr 
        835                 840                 845             


Glu Lys Val Val Gln Glu Thr Val Leu Val Glu Glu Arg Arg Val Val 
    850                 855                 860                 


His Ala Ser Gly Asp Ala Ser Tyr Ser Ala Gly Asp Ser Gly Asp Ala 
865                 870                 875                 880 


Ala Ala Gln Pro Ala Phe Thr Gly Ile Lys Gly Lys Glu Gly Ser Ala 
                885                 890                 895     


Leu Thr Glu Gly Ala Lys Glu Glu Gly Gly Glu Glu Val Ala Lys Ala 
            900                 905                 910         


Val Leu Glu Gln Glu Glu Thr Ala Ala Ala Ser Arg Glu Arg Gln Glu 
        915                 920                 925             


Glu Gln Ser Ala Ala Ile His Ile Ser Glu Thr Leu Glu Gln Lys Pro 
    930                 935                 940                 


His Phe Glu Ser Ser Thr Val Lys Thr Glu Thr Ile Ser Phe Gly Ser 
945                 950                 955                 960 


Val Ser Pro Gly Gly Val Lys Leu Glu Ile Ser Thr Lys Glu Val Pro 
                965                 970                 975     


Val Val His Thr Glu Thr Lys Thr Ile Thr Tyr Glu Ser Ser Gln Val 
            980                 985                 990         


Asp Pro Gly Thr Asp Leu Glu Pro  Gly Val Leu Met Ser  Ala Gln Thr 
        995                 1000                 1005             


Ile Thr  Ser Glu Thr Thr Ser  Thr Thr Thr Thr Thr  His Ile Thr 
    1010                 1015                 1020             


Lys Thr  Val Lys Gly Gly Ile  Ser Glu Thr Arg Ile  Glu Lys Arg 
    1025                 1030                 1035             


Ile Val  Ile Thr Gly Asp Ala  Asp Ile Asp His Asp  Gln Ala Leu 
    1040                 1045                 1050             


Ala Gln  Ala Ile Lys Glu Ala  Lys Glu Gln His Pro  Asp Met Ser 
    1055                 1060                 1065             


Val Thr  Lys Val Val Val His  Lys Glu Thr Glu Ile  Thr Pro Glu 
    1070                 1075                 1080             


Asp Gly  Glu Asp 
    1085         


<210>  3208
<211>  751
<212>  PRT
<213>  homo sapiens

<400>  3208

Met Ala Phe Arg Thr Ile Cys Val Leu Val Gly Val Phe Ile Cys Ser 
1               5                   10                  15      


Ile Cys Val Lys Gly Ser Ser Gln Pro Gln Ala Arg Val Tyr Leu Thr 
            20                  25                  30          


Phe Asp Glu Leu Arg Glu Thr Lys Thr Ser Glu Tyr Phe Ser Leu Ser 
        35                  40                  45              


His His Pro Leu Asp Tyr Arg Ile Leu Leu Met Asp Glu Asp Gln Asp 
    50                  55                  60                  


Arg Ile Tyr Val Gly Ser Lys Asp His Ile Leu Ser Leu Asn Ile Asn 
65                  70                  75                  80  


Asn Ile Ser Gln Glu Ala Leu Ser Val Phe Trp Pro Ala Ser Thr Ile 
                85                  90                  95      


Lys Val Glu Glu Cys Lys Met Ala Gly Lys Asp Pro Thr His Gly Cys 
            100                 105                 110         


Gly Asn Phe Val Arg Val Ile Gln Thr Phe Asn Arg Thr His Leu Tyr 
        115                 120                 125             


Val Cys Gly Ser Gly Ala Phe Ser Pro Val Cys Thr Tyr Leu Asn Arg 
    130                 135                 140                 


Gly Arg Arg Ser Glu Asp Gln Val Phe Met Ile Asp Ser Lys Cys Glu 
145                 150                 155                 160 


Ser Gly Lys Gly Arg Cys Ser Phe Asn Pro Asn Val Asn Thr Val Ser 
                165                 170                 175     


Val Met Ile Asn Glu Glu Leu Phe Ser Gly Met Tyr Ile Asp Phe Met 
            180                 185                 190         


Gly Thr Asp Ala Ala Ile Phe Arg Ser Leu Thr Lys Arg Asn Ala Val 
        195                 200                 205             


Arg Thr Asp Gln His Asn Ser Lys Trp Leu Ser Glu Pro Met Phe Val 
    210                 215                 220                 


Asp Ala His Val Ile Pro Asp Gly Thr Asp Pro Asn Asp Ala Lys Val 
225                 230                 235                 240 


Tyr Phe Phe Phe Lys Glu Lys Leu Thr Asp Asn Asn Arg Ser Thr Lys 
                245                 250                 255     


Gln Ile His Ser Met Ile Ala Arg Ile Cys Pro Asn Asp Thr Gly Gly 
            260                 265                 270         


Leu Arg Ser Leu Val Asn Lys Trp Thr Thr Phe Leu Lys Ala Arg Leu 
        275                 280                 285             


Val Cys Ser Val Thr Asp Glu Asp Gly Pro Glu Thr His Phe Asp Glu 
    290                 295                 300                 


Leu Glu Asp Val Phe Leu Leu Glu Thr Asp Asn Pro Arg Thr Thr Leu 
305                 310                 315                 320 


Val Tyr Gly Ile Phe Thr Thr Ser Ser Ser Val Phe Lys Gly Ser Ala 
                325                 330                 335     


Val Cys Val Tyr His Leu Ser Asp Ile Gln Thr Val Phe Asn Gly Pro 
            340                 345                 350         


Phe Ala His Lys Glu Gly Pro Asn His Gln Leu Ile Ser Tyr Gln Gly 
        355                 360                 365             


Arg Ile Pro Tyr Pro Arg Pro Gly Thr Cys Pro Gly Gly Ala Phe Thr 
    370                 375                 380                 


Pro Asn Met Arg Thr Thr Lys Glu Phe Pro Asp Asp Val Val Thr Phe 
385                 390                 395                 400 


Ile Arg Asn His Pro Leu Met Tyr Asn Ser Ile Tyr Pro Ile His Lys 
                405                 410                 415     


Arg Pro Leu Ile Val Arg Ile Gly Thr Asp Tyr Lys Tyr Thr Lys Ile 
            420                 425                 430         


Ala Val Asp Arg Val Asn Ala Ala Asp Gly Arg Tyr His Val Leu Phe 
        435                 440                 445             


Leu Gly Thr Asp Arg Gly Thr Val Gln Lys Val Val Val Leu Pro Thr 
    450                 455                 460                 


Asn Asn Ser Val Ser Gly Glu Leu Ile Leu Glu Glu Leu Glu Val Phe 
465                 470                 475                 480 


Lys Asn His Ala Pro Ile Thr Thr Met Lys Ile Ser Ser Lys Lys Gln 
                485                 490                 495     


Gln Leu Tyr Val Ser Ser Asn Glu Gly Val Ser Gln Val Ser Leu His 
            500                 505                 510         


Arg Cys His Ile Tyr Gly Thr Ala Cys Ala Asp Cys Cys Leu Ala Arg 
        515                 520                 525             


Asp Pro Tyr Cys Ala Trp Asp Gly His Ser Cys Ser Arg Phe Tyr Pro 
    530                 535                 540                 


Thr Gly Lys Arg Arg Ser Arg Arg Gln Asp Val Arg His Gly Asn Pro 
545                 550                 555                 560 


Leu Thr Gln Cys Arg Gly Phe Asn Leu Lys Ala Tyr Arg Asn Ala Ala 
                565                 570                 575     


Glu Ile Val Gln Tyr Gly Val Lys Asn Asn Thr Thr Phe Leu Glu Cys 
            580                 585                 590         


Ala Pro Lys Ser Pro Gln Ala Ser Ile Lys Trp Leu Leu Gln Lys Asp 
        595                 600                 605             


Lys Asp Arg Arg Lys Glu Val Lys Leu Asn Glu Arg Ile Ile Ala Thr 
    610                 615                 620                 


Ser Gln Gly Leu Leu Ile Arg Ser Val Gln Gly Ser Asp Gln Gly Leu 
625                 630                 635                 640 


Tyr His Cys Ile Ala Thr Glu Asn Ser Phe Lys Gln Thr Ile Ala Lys 
                645                 650                 655     


Ile Asn Phe Lys Val Leu Asp Ser Glu Met Val Ala Val Val Thr Asp 
            660                 665                 670         


Lys Trp Ser Pro Trp Thr Trp Ala Ser Ser Val Arg Ala Leu Pro Phe 
        675                 680                 685             


His Pro Lys Asp Ile Met Gly Ala Phe Ser His Ser Glu Met Gln Met 
    690                 695                 700                 


Ile Asn Gln Tyr Cys Lys Asp Thr Arg Gln Gln His Gln Gln Gly Asp 
705                 710                 715                 720 


Glu Ser Gln Lys Met Arg Gly Asp Tyr Gly Lys Leu Lys Ala Leu Ile 
                725                 730                 735     


Asn Ser Arg Lys Ser Arg Asn Arg Arg Asn Gln Leu Pro Glu Ser 
            740                 745                 750     


<210>  3209
<211>  874
<212>  PRT
<213>  homo sapiens

<400>  3209

Met Asp Glu Glu Glu Asp Asn Leu Ser Leu Leu Thr Ala Leu Leu Glu 
1               5                   10                  15      


Glu Asn Glu Ser Ala Leu Asp Cys Asn Ser Glu Glu Asn Asn Phe Leu 
            20                  25                  30          


Thr Arg Glu Asn Gly Glu Pro Asp Ala Phe Asp Glu Leu Phe Asp Ala 
        35                  40                  45              


Asp Gly Asp Gly Glu Ser Tyr Thr Glu Glu Ala Asp Asp Gly Glu Thr 
    50                  55                  60                  


Gly Glu Thr Arg Asp Glu Lys Glu Asn Leu Ala Thr Leu Phe Gly Asp 
65                  70                  75                  80  


Met Glu Asp Leu Thr Asp Glu Glu Glu Val Pro Ala Ser Gln Ser Thr 
                85                  90                  95      


Glu Asn Arg Val Leu Pro Ala Pro Ala Pro Arg Arg Glu Lys Thr Asn 
            100                 105                 110         


Glu Glu Leu Gln Glu Glu Leu Arg Asn Leu Gln Glu Gln Met Lys Ala 
        115                 120                 125             


Leu Gln Glu Gln Leu Lys Val Thr Thr Ile Lys Gln Thr Ala Ser Pro 
    130                 135                 140                 


Ala Arg Leu Gln Lys Ser Pro Glu Lys Ser Pro Arg Pro Pro Leu Lys 
145                 150                 155                 160 


Glu Arg Arg Val Gln Arg Ile Gln Glu Ser Thr Cys Phe Ser Ala Glu 
                165                 170                 175     


Leu Asp Val Pro Ala Leu Pro Arg Thr Lys Arg Val Ala Arg Thr Pro 
            180                 185                 190         


Lys Ala Ser Pro Pro Asp Pro Lys Ser Ser Ser Ser Arg Met Thr Ser 
        195                 200                 205             


Ala Pro Ser Gln Pro Leu Gln Thr Ile Ser Arg Asn Lys Pro Ser Gly 
    210                 215                 220                 


Ile Thr Arg Gly Gln Ile Val Gly Thr Pro Gly Ser Ser Gly Glu Thr 
225                 230                 235                 240 


Thr Gln Pro Ile Cys Val Glu Ala Phe Ser Gly Leu Arg Leu Arg Arg 
                245                 250                 255     


Pro Arg Val Ser Ser Thr Glu Met Asn Lys Lys Met Thr Gly Arg Lys 
            260                 265                 270         


Leu Ile Arg Leu Ser Gln Ile Lys Glu Lys Met Ala Arg Glu Lys Leu 
        275                 280                 285             


Glu Glu Ile Asp Trp Val Thr Phe Gly Val Ile Leu Lys Lys Val Thr 
    290                 295                 300                 


Pro Gln Ser Val Asn Ser Gly Lys Thr Phe Ser Ile Trp Lys Leu Asn 
305                 310                 315                 320 


Asp Leu Arg Asp Leu Thr Gln Cys Val Ser Leu Phe Leu Phe Gly Glu 
                325                 330                 335     


Val His Lys Ala Leu Trp Lys Thr Glu Gln Gly Thr Val Val Gly Ile 
            340                 345                 350         


Leu Asn Ala Asn Pro Met Lys Pro Lys Asp Gly Ser Glu Glu Val Cys 
        355                 360                 365             


Leu Ser Ile Asp His Pro Gln Lys Val Leu Ile Met Gly Glu Ala Leu 
    370                 375                 380                 


Asp Leu Gly Thr Cys Lys Ala Lys Lys Lys Asn Gly Glu Pro Cys Thr 
385                 390                 395                 400 


Gln Thr Val Asn Leu Arg Asp Cys Glu Tyr Cys Gln Tyr His Val Gln 
                405                 410                 415     


Ala Gln Tyr Lys Lys Leu Ser Ala Lys Arg Ala Asp Leu Gln Ser Thr 
            420                 425                 430         


Phe Ser Gly Gly Arg Ile Pro Lys Lys Phe Ala Arg Arg Gly Thr Ser 
        435                 440                 445             


Leu Lys Glu Arg Leu Cys Gln Asp Gly Phe Tyr Tyr Gly Gly Val Ser 
    450                 455                 460                 


Ser Ala Ser Tyr Ala Ala Ser Ile Ala Ala Ala Val Ala Pro Lys Lys 
465                 470                 475                 480 


Lys Ile Gln Thr Thr Leu Ser Asn Leu Val Val Lys Gly Thr Asn Leu 
                485                 490                 495     


Ile Ile Gln Glu Thr Arg Gln Lys Leu Gly Ile Pro Gln Lys Ser Leu 
            500                 505                 510         


Ser Cys Ser Glu Glu Phe Lys Glu Leu Met Asp Leu Pro Thr Cys Gly 
        515                 520                 525             


Ala Arg Asn Leu Lys Gln His Leu Ala Lys Ala Thr Ala Ser Gly Ile 
    530                 535                 540                 


Met Gly Ser Pro Lys Pro Ala Ile Lys Ser Ile Ser Ala Ser Ala Leu 
545                 550                 555                 560 


Leu Lys Gln Gln Lys Gln Arg Met Leu Glu Met Arg Arg Arg Lys Ser 
                565                 570                 575     


Glu Glu Ile Gln Lys Arg Phe Leu Gln Ser Ser Ser Glu Val Glu Ser 
            580                 585                 590         


Pro Ala Val Pro Ser Ser Ser Arg Gln Pro Pro Ala Gln Pro Pro Arg 
        595                 600                 605             


Thr Gly Ser Glu Phe Pro Arg Leu Glu Gly Ala Pro Ala Thr Met Thr 
    610                 615                 620                 


Pro Lys Leu Gly Arg Gly Val Leu Glu Gly Asp Asp Val Leu Phe Tyr 
625                 630                 635                 640 


Asp Glu Ser Pro Pro Pro Arg Pro Lys Leu Ser Ala Leu Ala Glu Ala 
                645                 650                 655     


Lys Lys Leu Ala Ala Ile Thr Lys Leu Arg Ala Lys Gly Gln Val Leu 
            660                 665                 670         


Thr Lys Thr Asn Pro Asn Ser Ile Lys Lys Lys Gln Lys Asp Pro Gln 
        675                 680                 685             


Asp Ile Leu Glu Val Lys Glu Arg Val Glu Lys Asn Thr Met Phe Ser 
    690                 695                 700                 


Ser Gln Ala Glu Asp Glu Leu Glu Pro Ala Arg Lys Lys Arg Arg Glu 
705                 710                 715                 720 


Gln Leu Ala Tyr Leu Glu Ser Glu Glu Phe Gln Lys Ile Leu Lys Ala 
                725                 730                 735     


Lys Ser Lys His Thr Gly Ile Leu Lys Glu Ala Glu Ala Glu Met Gln 
            740                 745                 750         


Glu Arg Tyr Phe Glu Pro Leu Val Lys Lys Glu Gln Met Glu Glu Lys 
        755                 760                 765             


Met Arg Asn Ile Arg Glu Val Lys Cys Arg Val Val Thr Cys Lys Thr 
    770                 775                 780                 


Cys Ala Tyr Thr His Phe Lys Leu Leu Glu Thr Cys Val Ser Glu Gln 
785                 790                 795                 800 


His Glu Tyr His Trp His Asp Gly Val Lys Arg Phe Phe Lys Cys Pro 
                805                 810                 815     


Cys Gly Asn Arg Ser Ile Ser Leu Asp Arg Leu Pro Asn Lys His Cys 
            820                 825                 830         


Ser Asn Cys Gly Leu Tyr Lys Trp Glu Arg Asp Gly Met Leu Lys Glu 
        835                 840                 845             


Lys Thr Gly Pro Lys Ile Gly Gly Glu Thr Leu Leu Pro Arg Gly Glu 
    850                 855                 860                 


Glu His Ala Lys Phe Leu Asn Ser Leu Lys 
865                 870                 


<210>  3210
<211>  458
<212>  PRT
<213>  homo sapiens

<400>  3210

Met Gly Gly Leu Gly Pro Arg Arg Ala Gly Thr Ser Arg Glu Arg Leu 
1               5                   10                  15      


Val Val Thr Gly Arg Ala Gly Trp Met Gly Met Gly Arg Gly Ala Gly 
            20                  25                  30          


Arg Ser Ala Leu Gly Phe Trp Pro Thr Leu Ala Phe Leu Leu Cys Ser 
        35                  40                  45              


Phe Pro Ala Ala Thr Ser Pro Cys Lys Ile Leu Lys Cys Asn Ser Glu 
    50                  55                  60                  


Phe Trp Ser Ala Thr Ser Gly Ser His Ala Pro Ala Ser Asp Asp Thr 
65                  70                  75                  80  


Pro Glu Phe Cys Ala Ala Leu Arg Ser Tyr Ala Leu Cys Thr Arg Arg 
                85                  90                  95      


Thr Ala Arg Thr Cys Arg Gly Asp Leu Ala Tyr His Ser Ala Val His 
            100                 105                 110         


Gly Ile Glu Asp Leu Met Ser Gln His Asn Cys Ser Lys Asp Gly Pro 
        115                 120                 125             


Thr Ser Gln Pro Arg Leu Arg Thr Leu Pro Pro Ala Gly Asp Ser Gln 
    130                 135                 140                 


Glu Arg Ser Asp Ser Pro Glu Ile Cys His Tyr Glu Lys Ser Phe His 
145                 150                 155                 160 


Lys His Ser Ala Thr Pro Asn Tyr Thr His Cys Gly Leu Phe Gly Asp 
                165                 170                 175     


Pro His Leu Arg Thr Phe Thr Asp Arg Phe Gln Thr Cys Lys Val Gln 
            180                 185                 190         


Gly Ala Trp Pro Leu Ile Asp Asn Asn Tyr Leu Asn Val Gln Val Thr 
        195                 200                 205             


Asn Thr Pro Val Leu Pro Gly Ser Ala Ala Thr Ala Thr Ser Lys Leu 
    210                 215                 220                 


Thr Ile Ile Phe Lys Asn Phe Gln Glu Cys Val Asp Gln Lys Val Tyr 
225                 230                 235                 240 


Gln Ala Glu Met Asp Glu Leu Pro Ala Ala Phe Val Asp Gly Ser Lys 
                245                 250                 255     


Asn Gly Gly Asp Lys His Gly Ala Asn Ser Leu Lys Ile Thr Glu Lys 
            260                 265                 270         


Val Ser Gly Gln His Val Glu Ile Gln Ala Lys Tyr Ile Gly Thr Thr 
        275                 280                 285             


Ile Val Val Arg Gln Val Gly Arg Tyr Leu Thr Phe Ala Val Arg Met 
    290                 295                 300                 


Pro Glu Glu Val Val Asn Ala Val Glu Asp Trp Asp Ser Gln Gly Leu 
305                 310                 315                 320 


Tyr Leu Cys Leu Arg Gly Cys Pro Leu Asn Gln Gln Ile Asp Phe Gln 
                325                 330                 335     


Ala Phe His Thr Asn Ala Glu Gly Thr Gly Ala Arg Arg Leu Ala Ala 
            340                 345                 350         


Ala Ser Pro Ala Pro Thr Ala Pro Glu Thr Phe Pro Tyr Glu Thr Ala 
        355                 360                 365             


Val Ala Lys Cys Lys Glu Lys Leu Pro Val Glu Asp Leu Tyr Tyr Gln 
    370                 375                 380                 


Ala Cys Val Phe Asp Leu Leu Thr Thr Gly Asp Val Asn Phe Thr Leu 
385                 390                 395                 400 


Ala Ala Tyr Tyr Ala Leu Glu Asp Val Lys Met Leu His Ser Asn Lys 
                405                 410                 415     


Asp Lys Leu His Leu Tyr Glu Arg Thr Arg Asp Leu Pro Gly Arg Ala 
            420                 425                 430         


Ala Ala Gly Leu Pro Leu Ala Pro Arg Pro Leu Leu Gly Ala Leu Val 
        435                 440                 445             


Pro Leu Leu Ala Leu Leu Pro Val Phe Cys 
    450                 455             


<210>  3211
<211>  1274
<212>  PRT
<213>  homo sapiens

<400>  3211

Met Leu Asp Pro Ser Ser Ser Glu Glu Glu Ser Asp Glu Ile Val Glu 
1               5                   10                  15      


Glu Glu Ser Gly Lys Glu Val Leu Gly Ser Ala Pro Ser Gly Ala Arg 
            20                  25                  30          


Leu Ser Pro Ser Arg Thr Ser Glu Gly Ser Ala Gly Ser Ala Gly Leu 
        35                  40                  45              


Gly Gly Gly Gly Ala Gly Ala Gly Ala Gly Val Gly Ala Gly Gly Gly 
    50                  55                  60                  


Gly Gly Ser Gly Ala Ser Ser Gly Gly Gly Ala Gly Gly Leu Gln Pro 
65                  70                  75                  80  


Ser Ser Arg Ala Gly Gly Gly Arg Pro Ser Ser Pro Ser Pro Ser Val 
                85                  90                  95      


Val Ser Glu Lys Glu Lys Glu Glu Leu Glu Arg Leu Gln Lys Glu Glu 
            100                 105                 110         


Glu Glu Arg Lys Lys Arg Leu Gln Leu Tyr Val Phe Val Met Arg Cys 
        115                 120                 125             


Ile Ala Tyr Pro Phe Asn Ala Lys Gln Pro Thr Asp Met Ala Arg Arg 
    130                 135                 140                 


Gln Gln Lys Ile Ser Lys Gln Gln Leu Gln Thr Val Lys Asp Arg Phe 
145                 150                 155                 160 


Gln Ala Phe Leu Asn Gly Glu Thr Gln Ile Met Ala Asp Glu Ala Phe 
                165                 170                 175     


Met Asn Ala Val Gln Ser Tyr Tyr Glu Val Phe Leu Lys Ser Asp Arg 
            180                 185                 190         


Val Ala Arg Met Val Gln Ser Gly Gly Cys Ser Ala Asn Asp Ser Arg 
        195                 200                 205             


Glu Val Phe Lys Lys His Ile Glu Lys Arg Val Arg Ser Leu Pro Glu 
    210                 215                 220                 


Ile Asp Gly Leu Ser Lys Glu Thr Val Leu Ser Ser Trp Met Ala Lys 
225                 230                 235                 240 


Phe Asp Ala Ile Tyr Arg Gly Glu Glu Asp Pro Arg Lys Gln Gln Ala 
                245                 250                 255     


Arg Met Thr Ala Ser Ala Ala Ser Glu Leu Ile Leu Ser Lys Glu Gln 
            260                 265                 270         


Leu Tyr Glu Met Phe Gln Asn Ile Leu Gly Ile Lys Lys Phe Glu His 
        275                 280                 285             


Gln Leu Leu Tyr Asn Ala Cys Gln Leu Asp Asn Pro Asp Glu Gln Ala 
    290                 295                 300                 


Ala Gln Ile Arg Arg Glu Leu Asp Gly Arg Leu Gln Met Ala Asp Gln 
305                 310                 315                 320 


Ile Ala Arg Glu Arg Lys Phe Pro Lys Phe Val Ser Lys Glu Met Glu 
                325                 330                 335     


Asn Met Tyr Ile Glu Glu Leu Lys Ser Ser Val Asn Leu Leu Met Ala 
            340                 345                 350         


Asn Leu Glu Ser Met Pro Val Ser Lys Gly Gly Glu Phe Lys Leu Gln 
        355                 360                 365             


Lys Leu Lys Arg Ser His Asn Ala Ser Ile Ile Asp Met Gly Glu Glu 
    370                 375                 380                 


Ser Glu Asn Gln Leu Ser Lys Ser Asp Val Val Leu Ser Phe Ser Leu 
385                 390                 395                 400 


Glu Val Val Ile Met Glu Val Gln Gly Leu Lys Ser Leu Ala Pro Asn 
                405                 410                 415     


Arg Ile Val Tyr Cys Thr Met Glu Val Glu Gly Gly Glu Lys Leu Gln 
            420                 425                 430         


Thr Asp Gln Ala Glu Ala Ser Lys Pro Thr Trp Gly Thr Gln Gly Asp 
        435                 440                 445             


Phe Ser Thr Thr His Ala Leu Pro Ala Val Lys Val Lys Leu Phe Thr 
    450                 455                 460                 


Glu Ser Thr Gly Val Leu Ala Leu Glu Asp Lys Glu Leu Gly Arg Val 
465                 470                 475                 480 


Ile Leu His Pro Thr Pro Asn Ser Pro Lys Gln Ser Glu Trp His Lys 
                485                 490                 495     


Met Thr Val Ser Lys Asn Cys Pro Asp Gln Asp Leu Lys Ile Lys Leu 
            500                 505                 510         


Ala Val Arg Met Asp Lys Pro Gln Asn Met Lys His Ser Gly Tyr Leu 
        515                 520                 525             


Trp Ala Ile Gly Lys Asn Val Trp Lys Arg Trp Lys Lys Arg Phe Phe 
    530                 535                 540                 


Val Leu Val Gln Val Ser Gln Tyr Thr Phe Ala Met Cys Ser Tyr Arg 
545                 550                 555                 560 


Glu Lys Lys Ala Glu Pro Gln Glu Leu Leu Gln Leu Asp Gly Tyr Thr 
                565                 570                 575     


Val Asp Tyr Thr Asp Pro Gln Pro Gly Leu Glu Gly Gly Arg Ala Phe 
            580                 585                 590         


Phe Asn Ala Val Lys Glu Gly Asp Thr Val Ile Phe Ala Ser Asp Asp 
        595                 600                 605             


Glu Gln Asp Arg Ile Leu Trp Val Gln Ala Met Tyr Arg Ala Thr Gly 
    610                 615                 620                 


Gln Ser His Lys Pro Val Pro Pro Thr Gln Val Gln Lys Leu Asn Ala 
625                 630                 635                 640 


Lys Gly Gly Asn Val Pro Gln Leu Asp Ala Pro Ile Ser Gln Phe Tyr 
                645                 650                 655     


Ala Asp Arg Ala Gln Lys His Gly Met Asp Glu Phe Ile Ser Ser Asn 
            660                 665                 670         


Pro Cys Asn Phe Asp His Ala Ser Leu Phe Glu Met Gly Trp Phe Ser 
        675                 680                 685             


Pro Gly Gln Val Phe Val Leu Asp Glu Tyr Cys Ala Arg Asn Gly Val 
    690                 695                 700                 


Arg Gly Cys His Arg His Leu Cys Tyr Leu Arg Asp Leu Leu Glu Arg 
705                 710                 715                 720 


Ala Glu Asn Gly Ala Met Ile Asp Pro Thr Leu Leu His Tyr Ser Phe 
                725                 730                 735     


Ala Phe Cys Ala Ser His Val His Gly Asn Arg Pro Asp Gly Ile Gly 
            740                 745                 750         


Thr Val Thr Val Glu Glu Lys Glu Arg Phe Glu Glu Ile Lys Glu Arg 
        755                 760                 765             


Leu Arg Val Leu Leu Glu Asn Gln Ile Thr His Phe Arg Tyr Cys Phe 
    770                 775                 780                 


Pro Phe Gly Arg Pro Glu Gly Ala Leu Lys Ala Thr Leu Ser Leu Leu 
785                 790                 795                 800 


Glu Arg Val Leu Met Lys Asp Ile Val Thr Pro Val Pro Gln Glu Glu 
                805                 810                 815     


Val Lys Thr Val Ile Arg Lys Cys Leu Glu Gln Ala Ala Leu Val Asn 
            820                 825                 830         


Tyr Ser Arg Leu Ser Glu Tyr Ala Lys Ile Glu Glu Asn Val Gly Arg 
        835                 840                 845             


Leu Ile Thr Pro Ala Lys Lys Leu Glu Asp Thr Ile Arg Leu Ala Glu 
    850                 855                 860                 


Leu Val Ile Glu Val Leu Gln Gln Asn Glu Glu His His Ala Glu Ala 
865                 870                 875                 880 


Phe Ala Trp Trp Ser Asp Leu Met Val Glu His Ala Glu Thr Phe Leu 
                885                 890                 895     


Ser Leu Phe Ala Val Asp Met Asp Ala Ala Leu Glu Val Gln Pro Pro 
            900                 905                 910         


Asp Thr Trp Asp Ser Phe Pro Leu Phe Gln Leu Leu Asn Asp Phe Leu 
        915                 920                 925             


Arg Thr Asp Tyr Asn Leu Cys Asn Gly Lys Phe His Lys His Leu Gln 
    930                 935                 940                 


Asp Leu Phe Ala Pro Leu Val Val Arg Tyr Val Asp Leu Met Glu Ser 
945                 950                 955                 960 


Ser Ile Ala Gln Ser Ile His Arg Gly Phe Glu Arg Glu Ser Trp Glu 
                965                 970                 975     


Pro Val Asn Asn Gly Ser Gly Thr Ser Glu Asp Leu Phe Trp Lys Leu 
            980                 985                 990         


Asp Ala Leu Gln Thr Phe Ile Arg  Asp Leu His Trp Pro  Glu Glu Glu 
        995                 1000                 1005             


Phe Gly  Lys His Leu Glu Gln  Arg Leu Lys Leu Met  Ala Ser Asp 
    1010                 1015                 1020             


Met Ile  Glu Ser Cys Val Lys  Arg Thr Arg Ile Ala  Phe Glu Val 
    1025                 1030                 1035             


Lys Leu  Gln Lys Thr Ser Arg  Ser Thr Asp Phe Arg  Val Pro Gln 
    1040                 1045                 1050             


Ser Ile  Cys Thr Met Phe Asn  Val Met Val Asp Ala  Lys Ala Gln 
    1055                 1060                 1065             


Ser Thr  Lys Leu Cys Ser Met  Glu Met Gly Gln Glu  His Gln Tyr 
    1070                 1075                 1080             


His Ser  Lys Ile Asp Glu Leu  Ile Glu Glu Thr Val  Lys Glu Met 
    1085                 1090                 1095             


Ile Thr  Leu Leu Val Ala Lys  Phe Val Thr Ile Leu  Glu Gly Val 
    1100                 1105                 1110             


Leu Ala  Lys Leu Ser Arg Tyr  Asp Glu Gly Thr Leu  Phe Ser Ser 
    1115                 1120                 1125             


Phe Leu  Ser Phe Thr Val Lys  Ala Ala Ser Lys Tyr  Val Asp Val 
    1130                 1135                 1140             


Pro Lys  Pro Gly Met Asp Val  Ala Asp Ala Tyr Val  Thr Phe Val 
    1145                 1150                 1155             


Arg His  Ser Gln Asp Val Leu  Arg Asp Lys Val Asn  Glu Glu Met 
    1160                 1165                 1170             


Tyr Ile  Glu Arg Leu Phe Asp  Gln Trp Tyr Asn Ser  Ser Met Asn 
    1175                 1180                 1185             


Val Ile  Cys Thr Trp Leu Thr  Asp Arg Met Asp Leu  Gln Leu His 
    1190                 1195                 1200             


Ile Tyr  Gln Leu Lys Thr Leu  Ile Arg Met Val Lys  Lys Thr Tyr 
    1205                 1210                 1215             


Arg Asp  Phe Arg Leu Gln Gly  Val Leu Asp Ser Thr  Leu Asn Ser 
    1220                 1225                 1230             


Lys Thr  Tyr Glu Thr Ile Arg  Asn Arg Leu Thr Val  Glu Glu Ala 
    1235                 1240                 1245             


Thr Ala  Ser Val Ser Glu Gly  Gly Gly Leu Gln Gly  Ile Ser Met 
    1250                 1255                 1260             


Lys Asp  Ser Asp Glu Glu Asp  Glu Glu Asp Asp 
    1265                 1270                 


<210>  3212
<211>  482
<212>  PRT
<213>  homo sapiens

<400>  3212

Met Val Met Glu Lys Pro Ser Pro Leu Leu Val Gly Arg Glu Phe Val 
1               5                   10                  15      


Arg Gln Tyr Tyr Thr Leu Leu Asn Lys Ala Pro Glu Tyr Leu His Arg 
            20                  25                  30          


Phe Tyr Gly Arg Asn Ser Ser Tyr Val His Gly Gly Val Asp Ala Ser 
        35                  40                  45              


Gly Lys Pro Gln Glu Ala Val Tyr Gly Gln Asn Asp Ile His His Lys 
    50                  55                  60                  


Val Leu Ser Leu Asn Phe Ser Glu Cys His Thr Lys Ile Arg His Val 
65                  70                  75                  80  


Asp Ala His Ala Thr Leu Ser Asp Gly Val Val Val Gln Val Met Gly 
                85                  90                  95      


Leu Leu Ser Asn Ser Gly Gln Pro Glu Arg Lys Phe Met Gln Thr Phe 
            100                 105                 110         


Val Leu Ala Pro Glu Gly Ser Val Pro Asn Lys Phe Tyr Val His Asn 
        115                 120                 125             


Asp Met Phe Arg Tyr Glu Asp Glu Val Phe Gly Asp Ser Glu Pro Glu 
    130                 135                 140                 


Leu Asp Glu Glu Ser Glu Asp Glu Val Glu Glu Glu Gln Glu Glu Arg 
145                 150                 155                 160 


Gln Pro Ser Pro Glu Pro Val Gln Glu Asn Ala Asn Ser Gly Tyr Tyr 
                165                 170                 175     


Glu Ala His Pro Val Thr Asn Gly Ile Glu Glu Pro Leu Glu Glu Ser 
            180                 185                 190         


Ser His Glu Pro Glu Pro Glu Pro Glu Ser Glu Thr Lys Thr Glu Glu 
        195                 200                 205             


Leu Lys Pro Gln Val Glu Glu Lys Asn Leu Glu Glu Leu Glu Glu Lys 
    210                 215                 220                 


Ser Thr Thr Pro Pro Pro Ala Glu Pro Val Ser Leu Pro Gln Glu Pro 
225                 230                 235                 240 


Pro Lys Ala Phe Ser Trp Ala Ser Val Thr Ser Lys Asn Leu Pro Pro 
                245                 250                 255     


Ser Gly Thr Val Ser Ser Ser Gly Ile Pro Pro His Val Lys Ala Pro 
            260                 265                 270         


Val Ser Gln Pro Arg Val Glu Ala Lys Pro Glu Val Gln Ser Gln Pro 
        275                 280                 285             


Pro Arg Val Arg Glu Gln Arg Pro Arg Glu Arg Pro Gly Phe Pro Pro 
    290                 295                 300                 


Arg Gly Pro Arg Pro Gly Arg Gly Asp Met Glu Gln Asn Asp Ser Asp 
305                 310                 315                 320 


Asn Arg Arg Ile Ile Arg Tyr Pro Asp Ser His Gln Leu Phe Val Gly 
                325                 330                 335     


Asn Leu Pro His Asp Ile Asp Glu Asn Glu Leu Lys Glu Phe Phe Met 
            340                 345                 350         


Ser Phe Gly Asn Val Val Glu Leu Arg Ile Asn Thr Lys Gly Val Gly 
        355                 360                 365             


Gly Lys Leu Pro Asn Phe Gly Phe Val Val Phe Asp Asp Ser Glu Pro 
    370                 375                 380                 


Val Gln Arg Ile Leu Ile Ala Lys Pro Ile Met Phe Arg Gly Glu Val 
385                 390                 395                 400 


Arg Leu Asn Val Glu Glu Lys Lys Thr Arg Ala Ala Arg Glu Arg Glu 
                405                 410                 415     


Thr Arg Gly Gly Gly Asp Asp Arg Arg Asp Ile Arg Arg Asn Asp Arg 
            420                 425                 430         


Gly Pro Gly Gly Pro Arg Gly Ile Val Gly Gly Gly Met Met Arg Asp 
        435                 440                 445             


Arg Asp Gly Arg Gly Pro Pro Pro Arg Gly Gly Met Ala Gln Lys Leu 
    450                 455                 460                 


Gly Ser Gly Arg Gly Thr Gly Gln Met Glu Gly Arg Phe Thr Gly Gln 
465                 470                 475                 480 


Arg Arg 
        


<210>  3213
<211>  112
<212>  PRT
<213>  homo sapiens

<400>  3213

Met Gln Asp Thr Gly Ser Val Val Pro Leu His Trp Phe Gly Phe Gly 
1               5                   10                  15      


Tyr Ala Ala Leu Val Ala Ser Gly Gly Ile Ile Gly Tyr Val Lys Ala 
            20                  25                  30          


Gly Ser Val Pro Ser Leu Ala Ala Gly Leu Leu Phe Gly Ser Leu Ala 
        35                  40                  45              


Gly Leu Gly Ala Tyr Gln Leu Ser Gln Asp Pro Arg Asn Val Trp Val 
    50                  55                  60                  


Phe Leu Ala Thr Ser Gly Thr Leu Ala Gly Ile Met Gly Met Arg Phe 
65                  70                  75                  80  


Tyr His Ser Gly Lys Phe Met Pro Ala Gly Leu Ile Ala Gly Ala Ser 
                85                  90                  95      


Leu Leu Met Val Ala Lys Val Gly Val Ser Met Phe Asn Arg Pro His 
            100                 105                 110         


<210>  3214
<211>  1429
<212>  PRT
<213>  homo sapiens

<400>  3214

Met Thr Asn Pro Trp Glu Glu Lys Val Cys Lys Met Ala Gln Thr Ser 
1               5                   10                  15      


Leu Leu Gln Gly Lys Gln Phe Tyr Cys Arg Glu Trp Val Phe His Lys 
            20                  25                  30          


Leu Gln His Cys Leu Gln Glu Lys Ser Asn Cys Cys Asn Ser Ala Val 
        35                  40                  45              


Asn Ala Pro Ser Leu Val Met Asn Ser Gly Asn Asn Ala Ser Gly Val 
    50                  55                  60                  


Ser Gly Lys Gly Ala Ala Trp Gly Val Leu Leu Val Gly Gly Pro Gly 
65                  70                  75                  80  


Ser Gly Lys Thr Ala Leu Cys Thr Glu Leu Leu Trp Pro Ser Ser Pro 
                85                  90                  95      


Ala Ser Leu Gln Arg Gly Leu His Arg Gln Ala Leu Ala Phe His Phe 
            100                 105                 110         


Cys Lys Ala Gln Asp Ser Asp Thr Leu Cys Val Gly Gly Phe Ile Arg 
        115                 120                 125             


Gly Leu Val Ala Gln Ile Cys Arg Ser Gly Leu Leu Gln Gly Tyr Glu 
    130                 135                 140                 


Asp Lys Leu Arg Asp Pro Ala Val Gln Ser Leu Leu Gln Pro Gly Glu 
145                 150                 155                 160 


Cys Glu Arg Asn Pro Ala Glu Ala Phe Lys Arg Cys Val Leu Leu Pro 
                165                 170                 175     


Leu Leu Gly Met Lys Pro Pro Gln Gln Ser Leu Tyr Leu Leu Val Asp 
            180                 185                 190         


Ser Val Asp Glu Gly Cys Asn Ile Thr Glu Gly Glu Gln Thr Ser Thr 
        195                 200                 205             


Ser Leu Ser Gly Thr Val Ala Ala Leu Leu Ala Gly His His Glu Phe 
    210                 215                 220                 


Phe Pro Pro Trp Leu Leu Leu Leu Cys Ser Ala Arg Lys Gln Ser Lys 
225                 230                 235                 240 


Ala Val Thr Lys Met Phe Thr Gly Phe Arg Lys Ile Ser Leu Asp Asp 
                245                 250                 255     


Leu Arg Lys Ala Tyr Ile Val Lys Asp Val Gln Gln Tyr Ile Leu His 
            260                 265                 270         


Arg Leu Asp Gln Glu Glu Ala Leu Arg Gln His Leu Thr Lys Glu Thr 
        275                 280                 285             


Ala Glu Met Leu Asn Gln Leu His Ile Lys Ser Ser Gly Cys Phe Leu 
    290                 295                 300                 


Tyr Leu Glu Arg Val Leu Asp Gly Val Val Glu Asn Phe Ile Met Leu 
305                 310                 315                 320 


Arg Glu Ile Arg Asp Ile Pro Gly Thr Leu Asn Gly Leu Tyr Leu Trp 
                325                 330                 335     


Leu Cys Gln Arg Leu Phe Val Arg Lys Gln Phe Ala Lys Val Gln Pro 
            340                 345                 350         


Ile Leu Asn Val Ile Leu Ala Ala Cys Arg Pro Leu Thr Ile Thr Glu 
        355                 360                 365             


Leu Tyr His Ala Val Trp Thr Lys Asn Met Ser Leu Thr Leu Glu Asp 
    370                 375                 380                 


Phe Gln Arg Lys Leu Asp Ile Leu Ser Lys Leu Leu Val Asp Gly Leu 
385                 390                 395                 400 


Gly Asn Thr Lys Ile Leu Phe His Tyr Ser Phe Ala Glu Trp Leu Leu 
                405                 410                 415     


Asp Val Lys His Cys Thr Gln Lys Tyr Leu Cys Asn Ala Ala Glu Gly 
            420                 425                 430         


His Arg Met Leu Ala Met Ser Tyr Thr Cys Gln Ala Lys Asn Leu Thr 
        435                 440                 445             


Pro Leu Glu Ala Gln Glu Phe Ala Leu His Leu Ile Asn Ser Asn Leu 
    450                 455                 460                 


Gln Leu Glu Thr Ala Glu Leu Ala Leu Trp Met Ile Trp Asn Gly Thr 
465                 470                 475                 480 


Pro Val Arg Asp Ser Leu Ser Thr Leu Ile Pro Lys Glu Gln Glu Val 
                485                 490                 495     


Leu Gln Leu Leu Val Lys Ala Gly Ala His Val Asn Ser Glu Asp Asp 
            500                 505                 510         


Arg Thr Ser Cys Ile Val Arg Gln Ala Leu Glu Arg Glu Asp Ser Ile 
        515                 520                 525             


Arg Thr Leu Leu Asp Asn Gly Ala Ser Val Asn Gln Cys Asp Ser Asn 
    530                 535                 540                 


Gly Arg Thr Leu Leu Ala Asn Ala Ala Tyr Ser Gly Ser Leu Asp Val 
545                 550                 555                 560 


Val Asn Leu Leu Val Ser Arg Gly Ala Asp Leu Glu Ile Glu Asp Ala 
                565                 570                 575     


His Gly His Thr Pro Leu Thr Leu Ala Ala Arg Gln Gly His Thr Lys 
            580                 585                 590         


Val Val Asn Cys Leu Ile Gly Cys Gly Ala Asn Ile Asn His Thr Asp 
        595                 600                 605             


Gln Asp Gly Trp Thr Ala Leu Arg Ser Ala Ala Trp Gly Gly His Thr 
    610                 615                 620                 


Glu Val Val Ser Ala Leu Leu Tyr Ala Gly Val Lys Val Asp Cys Ala 
625                 630                 635                 640 


Asp Ala Asp Ser Arg Thr Ala Leu Arg Ala Ala Ala Trp Gly Gly His 
                645                 650                 655     


Glu Asp Ile Val Leu Asn Leu Leu Gln His Gly Ala Glu Val Asn Lys 
            660                 665                 670         


Ala Asp Asn Glu Gly Arg Thr Ala Leu Ile Ala Ala Ala Tyr Met Gly 
        675                 680                 685             


His Arg Glu Ile Val Glu His Leu Leu Asp His Gly Ala Glu Val Asn 
    690                 695                 700                 


His Glu Asp Val Asp Gly Arg Thr Ala Leu Ser Val Ala Ala Leu Cys 
705                 710                 715                 720 


Val Pro Ala Ser Lys Gly His Ala Ser Val Val Ser Leu Leu Ile Asp 
                725                 730                 735     


Arg Gly Ala Glu Val Asp His Cys Asp Lys Asp Gly Met Thr Pro Leu 
            740                 745                 750         


Leu Val Ala Ala Tyr Glu Gly His Val Asp Val Val Asp Leu Leu Leu 
        755                 760                 765             


Glu Gly Gly Ala Asp Val Asp His Thr Asp Asn Asn Gly Arg Thr Pro 
    770                 775                 780                 


Leu Leu Ala Ala Ala Ser Met Gly His Ala Ser Val Val Asn Thr Leu 
785                 790                 795                 800 


Leu Phe Trp Gly Ala Ala Val Asp Ser Ile Asp Ser Glu Gly Arg Thr 
                805                 810                 815     


Val Leu Ser Ile Ala Ser Ala Gln Gly Asn Val Glu Val Val Arg Thr 
            820                 825                 830         


Leu Leu Asp Arg Gly Leu Asp Glu Asn His Arg Asp Asp Ala Gly Trp 
        835                 840                 845             


Thr Pro Leu His Met Ala Ala Phe Glu Gly His Arg Leu Ile Cys Glu 
    850                 855                 860                 


Ala Leu Ile Glu Gln Gly Ala Arg Thr Asn Glu Ile Asp Asn Asp Gly 
865                 870                 875                 880 


Arg Ile Pro Phe Ile Leu Ala Ser Gln Glu Gly His Tyr Asp Cys Val 
                885                 890                 895     


Gln Ile Leu Leu Glu Asn Lys Ser Asn Ile Asp Gln Arg Gly Tyr Asp 
            900                 905                 910         


Gly Arg Asn Ala Leu Arg Val Ala Ala Leu Glu Gly His Arg Asp Ile 
        915                 920                 925             


Val Glu Leu Leu Phe Ser His Gly Ala Asp Val Asn Cys Lys Asp Ala 
    930                 935                 940                 


Asp Gly Arg Pro Thr Leu Tyr Ile Leu Ala Leu Glu Asn Gln Leu Thr 
945                 950                 955                 960 


Met Ala Glu Tyr Phe Leu Glu Asn Gly Ala Asn Val Glu Ala Ser Asp 
                965                 970                 975     


Ala Glu Gly Arg Thr Ala Leu His Val Ser Cys Trp Gln Gly His Met 
            980                 985                 990         


Glu Met Val Gln Val Leu Ile Ala  Tyr His Ala Asp Val  Asn Ala Ala 
        995                 1000                 1005             


Asp Asn  Glu Lys Arg Ser Ala  Leu Gln Ser Ala Ala  Trp Gln Gly 
    1010                 1015                 1020             


His Val  Lys Val Val Gln Leu  Leu Ile Glu His Gly  Ala Val Val 
    1025                 1030                 1035             


Asp His  Thr Cys Asn Gln Gly  Ala Thr Ala Leu Cys  Ile Ala Ala 
    1040                 1045                 1050             


Gln Glu  Gly His Ile Asp Val  Val Gln Val Leu Leu  Glu His Gly 
    1055                 1060                 1065             


Ala Asp  Pro Asn His Ala Asp  Gln Phe Gly Arg Thr  Ala Met Arg 
    1070                 1075                 1080             


Val Ala  Ala Lys Asn Gly His  Ser Gln Ile Ile Lys  Leu Leu Glu 
    1085                 1090                 1095             


Lys Tyr  Gly Ala Ser Ser Leu  Asn Gly Cys Ser Pro  Ser Pro Val 
    1100                 1105                 1110             


His Thr  Met Glu Gln Lys Pro  Leu Gln Ser Leu Ser  Ser Lys Val 
    1115                 1120                 1125             


Gln Ser  Leu Thr Ile Lys Ser  Asn Ser Ser Gly Ser  Thr Gly Gly 
    1130                 1135                 1140             


Gly Asp  Met Gln Pro Ser Leu  Arg Gly Leu Pro Asn  Gly Pro Thr 
    1145                 1150                 1155             


His Ala  Phe Ser Ser Pro Ser  Glu Ser Pro Asp Ser  Thr Val Asp 
    1160                 1165                 1170             


Arg Gln  Lys Ser Ser Leu Ser  Asn Asn Ser Leu Lys  Ser Ser Lys 
    1175                 1180                 1185             


Asn Ser  Ser Leu Arg Thr Thr  Ser Ser Thr Ala Thr  Ala Gln Thr 
    1190                 1195                 1200             


Val Pro  Ile Asp Ser Phe His  Asn Leu Ser Phe Thr  Glu Gln Ile 
    1205                 1210                 1215             


Gln Gln  His Ser Leu Pro Arg  Ser Arg Ser Arg Gln  Ser Ile Val 
    1220                 1225                 1230             


Ser Pro  Ser Ser Thr Thr Gln  Ser Leu Gly Gln Ser  His Asn Ser 
    1235                 1240                 1245             


Pro Ser  Ser Glu Phe Glu Trp  Ser Gln Val Lys Pro  Ser Leu Lys 
    1250                 1255                 1260             


Ser Thr  Lys Ala Ser Lys Gly  Gly Lys Ser Glu Asn  Ser Ala Lys 
    1265                 1270                 1275             


Ser Gly  Ser Ala Gly Lys Lys  Ala Lys Gln Ser Asn  Ser Ser Gln 
    1280                 1285                 1290             


Pro Lys  Val Leu Glu Tyr Glu  Met Thr Gln Phe Asp  Arg Arg Gly 
    1295                 1300                 1305             


Pro Ile  Ala Lys Ser Gly Thr  Ala Ala Pro Pro Lys  Gln Met Pro 
    1310                 1315                 1320             


Ala Glu  Ser Gln Cys Lys Ile  Met Ile Pro Ser Ala  Gln Gln Glu 
    1325                 1330                 1335             


Ile Gly  Arg Ser Gln Gln Gln  Phe Leu Ile His Gln  Gln Ser Gly 
    1340                 1345                 1350             


Glu Gln  Lys Lys Arg Asn Gly  Ile Met Thr Asn Pro  Asn Tyr His 
    1355                 1360                 1365             


Leu Gln  Ser Asn Gln Val Phe  Leu Gly Arg Val Ser  Val Pro Arg 
    1370                 1375                 1380             


Thr Met  Gln Asp Arg Gly His  Gln Glu Val Leu Glu  Gly Tyr Pro 
    1385                 1390                 1395             


Ser Ser  Glu Thr Glu Leu Ser  Leu Lys Gln Ala Leu  Lys Leu Gln 
    1400                 1405                 1410             


Ile Glu  Gly Ser Asp Pro Ser  Phe Asn Tyr Lys Lys  Glu Thr Pro 
    1415                 1420                 1425             


Leu 
    


<210>  3215
<211>  1015
<212>  PRT
<213>  homo sapiens

<400>  3215

Met Gly Pro Pro Leu Pro Leu Leu Leu Leu Leu Leu Leu Leu Leu Pro 
1               5                   10                  15      


Pro Arg Val Leu Pro Ala Ala Pro Ser Ser Val Pro Arg Gly Arg Gln 
            20                  25                  30          


Leu Pro Gly Arg Leu Gly Cys Leu Leu Glu Glu Gly Leu Cys Gly Ala 
        35                  40                  45              


Ser Glu Ala Cys Val Asn Asp Gly Val Phe Gly Arg Cys Gln Lys Val 
    50                  55                  60                  


Pro Ala Met Asp Phe Tyr Arg Tyr Glu Val Ser Pro Val Ala Leu Gln 
65                  70                  75                  80  


Arg Leu Arg Val Ala Leu Gln Lys Leu Ser Gly Thr Gly Phe Thr Trp 
                85                  90                  95      


Gln Asp Asp Tyr Thr Gln Tyr Val Met Asp Gln Glu Leu Ala Asp Leu 
            100                 105                 110         


Pro Lys Thr Tyr Leu Arg Arg Pro Glu Ala Ser Ser Pro Ala Arg Pro 
        115                 120                 125             


Ser Lys His Ser Val Gly Ser Glu Arg Arg Tyr Ser Arg Glu Gly Gly 
    130                 135                 140                 


Ala Ala Leu Ala Asn Ala Leu Arg Arg His Leu Pro Phe Leu Glu Ala 
145                 150                 155                 160 


Leu Ser Gln Ala Pro Ala Ser Asp Val Leu Ala Arg Thr His Thr Ala 
                165                 170                 175     


Gln Asp Arg Pro Pro Ala Glu Gly Asp Asp Arg Phe Ser Glu Ser Ile 
            180                 185                 190         


Leu Thr Tyr Val Ala His Thr Ser Ala Leu Thr Tyr Pro Pro Gly Ser 
        195                 200                 205             


Arg Thr Gln Leu Arg Glu Asp Leu Leu Pro Arg Thr Leu Gly Gln Leu 
    210                 215                 220                 


Gln Pro Asp Glu Leu Ser Pro Lys Val Asp Ser Gly Val Asp Arg His 
225                 230                 235                 240 


His Leu Met Ala Ala Leu Ser Ala Tyr Ala Ala Gln Arg Pro Pro Ala 
                245                 250                 255     


Pro Pro Gly Glu Gly Ser Leu Glu Pro Gln Tyr Leu Leu Arg Ala Pro 
            260                 265                 270         


Ser Arg Met Pro Arg Pro Leu Leu Ala Pro Ala Ala Pro Gln Lys Trp 
        275                 280                 285             


Pro Ser Pro Leu Gly Asp Ser Glu Asp Pro Ser Ser Thr Gly Asp Gly 
    290                 295                 300                 


Ala Arg Ile His Thr Leu Leu Lys Asp Leu Gln Arg Gln Pro Ala Glu 
305                 310                 315                 320 


Val Arg Gly Leu Ser Gly Leu Glu Leu Asp Gly Met Ala Glu Leu Met 
                325                 330                 335     


Ala Gly Leu Met Gln Gly Val Asp His Gly Val Ala Arg Gly Ser Pro 
            340                 345                 350         


Gly Arg Ala Ala Leu Gly Glu Ser Gly Glu Gln Ala Asp Gly Pro Lys 
        355                 360                 365             


Ala Thr Leu Arg Gly Asp Ser Phe Pro Asp Asp Gly Val Gln Asp Asp 
    370                 375                 380                 


Asp Asp Arg Leu Tyr Gln Glu Val His Arg Leu Ser Ala Thr Leu Gly 
385                 390                 395                 400 


Gly Leu Leu Gln Asp His Gly Ser Arg Leu Leu Pro Gly Ala Leu Pro 
                405                 410                 415     


Phe Ala Arg Pro Leu Asp Met Glu Arg Lys Lys Ser Glu His Pro Glu 
            420                 425                 430         


Ser Ser Leu Ser Ser Glu Glu Glu Thr Ala Gly Val Glu Asn Val Lys 
        435                 440                 445             


Ser Gln Thr Tyr Ser Lys Asp Leu Leu Gly Gln Gln Pro His Ser Glu 
    450                 455                 460                 


Pro Gly Ala Ala Ala Phe Gly Glu Leu Gln Asn Gln Met Pro Gly Pro 
465                 470                 475                 480 


Ser Lys Glu Glu Gln Ser Leu Pro Ala Gly Ala Gln Glu Ala Leu Ser 
                485                 490                 495     


Asp Gly Leu Gln Leu Glu Val Gln Pro Ser Glu Glu Glu Ala Arg Gly 
            500                 505                 510         


Tyr Ile Val Thr Asp Arg Asp Pro Leu Arg Pro Glu Glu Gly Arg Arg 
        515                 520                 525             


Leu Val Glu Asp Val Ala Arg Leu Leu Gln Val Pro Ser Ser Ala Phe 
    530                 535                 540                 


Ala Asp Val Glu Val Leu Gly Pro Ala Val Thr Phe Lys Val Ser Ala 
545                 550                 555                 560 


Asn Val Gln Asn Val Thr Thr Glu Asp Val Glu Lys Ala Thr Val Asp 
                565                 570                 575     


Asn Lys Asp Lys Leu Glu Glu Thr Ser Gly Leu Lys Ile Leu Gln Thr 
            580                 585                 590         


Gly Val Gly Ser Lys Ser Lys Leu Lys Phe Leu Pro Pro Gln Ala Glu 
        595                 600                 605             


Gln Glu Asp Ser Thr Lys Phe Ile Ala Leu Thr Leu Val Ser Leu Ala 
    610                 615                 620                 


Cys Ile Leu Gly Val Leu Leu Ala Ser Gly Leu Ile Tyr Cys Leu Arg 
625                 630                 635                 640 


His Ser Ser Gln His Arg Leu Lys Glu Lys Leu Ser Gly Leu Gly Gly 
                645                 650                 655     


Asp Pro Gly Ala Asp Ala Thr Ala Ala Tyr Gln Glu Leu Cys Arg Gln 
            660                 665                 670         


Arg Met Ala Thr Arg Pro Pro Asp Arg Pro Glu Gly Pro His Thr Ser 
        675                 680                 685             


Arg Ile Ser Ser Val Ser Ser Gln Phe Ser Asp Gly Pro Ile Pro Ser 
    690                 695                 700                 


Pro Ser Ala Arg Ser Ser Ala Ser Ser Trp Ser Glu Glu Pro Val Gln 
705                 710                 715                 720 


Ser Asn Met Asp Ile Ser Thr Gly His Met Ile Leu Ser Tyr Met Glu 
                725                 730                 735     


Asp His Leu Lys Asn Lys Asn Arg Leu Glu Lys Glu Trp Glu Ala Leu 
            740                 745                 750         


Cys Ala Tyr Gln Ala Glu Pro Asn Ser Ser Phe Val Ala Gln Arg Glu 
        755                 760                 765             


Glu Asn Val Pro Lys Asn Arg Ser Leu Ala Val Leu Thr Tyr Asp His 
    770                 775                 780                 


Ser Arg Val Leu Leu Lys Ala Glu Asn Ser His Ser His Ser Asp Tyr 
785                 790                 795                 800 


Ile Asn Ala Ser Pro Ile Met Asp His Asp Pro Arg Asn Pro Ala Tyr 
                805                 810                 815     


Ile Ala Thr Gln Gly Pro Leu Pro Ala Thr Val Ala Asp Phe Trp Gln 
            820                 825                 830         


Met Val Trp Glu Ser Gly Cys Val Val Ile Val Met Leu Thr Pro Leu 
        835                 840                 845             


Ala Glu Asn Gly Val Arg Gln Cys Tyr His Tyr Trp Pro Asp Glu Gly 
    850                 855                 860                 


Ser Asn Leu Tyr His Ile Tyr Glu Val Asn Leu Val Ser Glu His Ile 
865                 870                 875                 880 


Trp Cys Glu Asp Phe Leu Val Arg Ser Phe Tyr Leu Lys Asn Leu Gln 
                885                 890                 895     


Thr Asn Glu Thr Arg Thr Val Thr Gln Phe His Phe Leu Ser Trp Tyr 
            900                 905                 910         


Asp Arg Gly Val Pro Ser Ser Ser Arg Ser Leu Leu Asp Phe Arg Arg 
        915                 920                 925             


Lys Val Asn Lys Cys Tyr Arg Gly Arg Ser Cys Pro Ile Ile Val His 
    930                 935                 940                 


Cys Ser Asp Gly Ala Gly Arg Ser Gly Thr Tyr Val Leu Ile Asp Met 
945                 950                 955                 960 


Val Leu Asn Lys Met Ala Lys Gly Ala Lys Glu Ile Asp Ile Ala Ala 
                965                 970                 975     


Thr Leu Glu His Leu Arg Asp Gln Arg Pro Gly Met Val Gln Thr Lys 
            980                 985                 990         


Glu Gln Phe Glu Phe Ala Leu Thr  Ala Val Ala Glu Glu  Val Asn Ala 
        995                 1000                 1005             


Ile Leu  Lys Ala Leu Pro Gln  
    1010                 1015 


<210>  3216
<211>  539
<212>  PRT
<213>  homo sapiens

<400>  3216

Met Gly Arg Ala Gly Gly Gly Gly Pro Gly Arg Gly Pro Pro Pro Leu 
1               5                   10                  15      


Leu Leu Phe Leu Gly Ala Ala Leu Val Leu Ala Ser Gly Ala Val Pro 
            20                  25                  30          


Ala Arg Glu Ala Gly Ser Ala Val Glu Ala Glu Glu Leu Val Lys Gly 
        35                  40                  45              


Ser Pro Ala Trp Glu Pro Pro Ala Asn Asp Thr Arg Glu Glu Ala Gly 
    50                  55                  60                  


Pro Pro Ala Ala Gly Glu Asp Glu Ala Ser Trp Thr Ala Pro Gly Gly 
65                  70                  75                  80  


Glu Leu Ala Gly Pro Glu Glu Val Leu Gln Glu Ser Ala Ala Val Thr 
                85                  90                  95      


Gly Thr Ala Trp Leu Glu Ala Asp Ser Pro Gly Leu Gly Gly Val Thr 
            100                 105                 110         


Ala Glu Ala Gly Ser Gly Asp Ala Gln Ala Leu Pro Ala Thr Leu Gln 
        115                 120                 125             


Ala Pro His Glu Val Leu Gly Gln Ser Ile Met Pro Pro Ala Ile Pro 
    130                 135                 140                 


Glu Ala Thr Glu Ala Ser Gly Pro Pro Ser Pro Thr Pro Gly Asp Lys 
145                 150                 155                 160 


Leu Ser Pro Ala Ser Glu Leu Pro Lys Glu Ser Pro Leu Glu Val Trp 
                165                 170                 175     


Leu Asn Leu Gly Gly Ser Thr Pro Asp Pro Gln Gly Pro Glu Leu Thr 
            180                 185                 190         


Tyr Pro Phe Gln Gly Thr Leu Glu Pro Gln Pro Ala Ser Asp Ile Ile 
        195                 200                 205             


Asp Ile Asp Tyr Phe Glu Gly Leu Asp Gly Glu Gly Arg Gly Ala Asp 
    210                 215                 220                 


Leu Gly Ser Phe Pro Gly Ser Pro Gly Thr Ser Glu Asn His Pro Asp 
225                 230                 235                 240 


Thr Glu Gly Glu Thr Pro Ser Trp Ser Leu Leu Asp Leu Tyr Asp Asp 
                245                 250                 255     


Phe Thr Pro Phe Asp Glu Ser Asp Phe Tyr Pro Thr Thr Ser Phe Tyr 
            260                 265                 270         


Asp Asp Leu Asp Glu Glu Glu Glu Glu Glu Glu Asp Asp Lys Asp Ala 
        275                 280                 285             


Val Gly Gly Gly Asp Leu Glu Asp Glu Asn Glu Leu Leu Val Pro Thr 
    290                 295                 300                 


Gly Lys Pro Gly Leu Gly Pro Gly Thr Gly Gln Pro Thr Ser Arg Trp 
305                 310                 315                 320 


His Ala Val Pro Pro Gln His Thr Leu Gly Ser Val Pro Gly Ser Ser 
                325                 330                 335     


Ile Ala Leu Arg Pro Arg Pro Gly Glu Pro Gly Arg Asp Leu Ala Ser 
            340                 345                 350         


Ser Glu Asn Gly Thr Glu Cys Arg Ser Gly Phe Val Arg His Asn Gly 
        355                 360                 365             


Ser Cys Arg Ser Val Cys Asp Leu Phe Pro Ser Tyr Cys His Asn Gly 
    370                 375                 380                 


Gly Gln Cys Tyr Leu Val Glu Asn Ile Gly Ala Phe Cys Arg Cys Asn 
385                 390                 395                 400 


Thr Gln Asp Tyr Ile Trp His Lys Gly Met Arg Cys Glu Ser Ile Ile 
                405                 410                 415     


Thr Asp Phe Gln Val Met Cys Val Ala Val Gly Ser Ala Ala Leu Val 
            420                 425                 430         


Leu Leu Leu Leu Phe Met Met Thr Val Phe Phe Ala Lys Lys Leu Tyr 
        435                 440                 445             


Leu Leu Lys Thr Glu Asn Thr Lys Leu Arg Arg Thr Asn Lys Phe Arg 
    450                 455                 460                 


Thr Pro Ser Glu Leu His Asn Asp Asn Phe Ser Leu Ser Thr Ile Ala 
465                 470                 475                 480 


Glu Gly Ser His Pro Asn Asp Asp Pro Ser Ala Pro His Lys Ile Gln 
                485                 490                 495     


Glu Val Leu Lys Ser Cys Leu Lys Glu Glu Glu Ser Phe Asn Ile Gln 
            500                 505                 510         


Asn Ser Met Ser Pro Lys Leu Glu Gly Gly Lys Gly Asp Gln Ala Asp 
        515                 520                 525             


Leu Asp Val Asn Cys Leu Gln Asn Asn Leu Thr 
    530                 535                 


<210>  3217
<211>  436
<212>  PRT
<213>  homo sapiens

<400>  3217

Met Val Gly Phe Gly Ala Asn Arg Arg Ala Gly Arg Leu Pro Ser Leu 
1               5                   10                  15      


Val Leu Val Val Leu Leu Val Val Ile Val Val Leu Ala Phe Asn Tyr 
            20                  25                  30          


Trp Ser Ile Ser Ser Arg His Val Leu Leu Gln Glu Glu Val Ala Glu 
        35                  40                  45              


Leu Gln Gly Gln Val Gln Arg Thr Glu Val Ala Arg Gly Arg Leu Glu 
    50                  55                  60                  


Lys Arg Asn Ser Asp Leu Leu Leu Leu Val Asp Thr His Lys Lys Gln 
65                  70                  75                  80  


Ile Asp Gln Lys Glu Ala Asp Tyr Gly Arg Leu Ser Ser Arg Leu Gln 
                85                  90                  95      


Ala Arg Glu Gly Leu Gly Lys Arg Cys Glu Asp Asp Lys Val Lys Leu 
            100                 105                 110         


Gln Asn Asn Ile Ser Tyr Gln Met Ala Asp Ile His His Leu Lys Glu 
        115                 120                 125             


Gln Leu Ala Glu Leu Arg Gln Glu Phe Leu Arg Gln Glu Asp Gln Leu 
    130                 135                 140                 


Gln Asp Tyr Arg Lys Asn Asn Thr Tyr Leu Val Lys Arg Leu Glu Tyr 
145                 150                 155                 160 


Glu Ser Phe Gln Cys Gly Gln Gln Met Lys Glu Leu Arg Ala Gln His 
                165                 170                 175     


Glu Glu Asn Ile Lys Lys Leu Ala Asp Gln Phe Leu Glu Glu Gln Lys 
            180                 185                 190         


Gln Glu Thr Gln Lys Ile Gln Ser Asn Asp Gly Lys Glu Leu Asp Ile 
        195                 200                 205             


Asn Asn Gln Val Val Pro Lys Asn Ile Pro Lys Val Ala Glu Asn Val 
    210                 215                 220                 


Ala Asp Lys Asn Glu Glu Pro Ser Ser Asn His Ile Pro His Gly Lys 
225                 230                 235                 240 


Glu Gln Ile Lys Arg Gly Gly Asp Ala Gly Met Pro Gly Ile Glu Glu 
                245                 250                 255     


Asn Asp Leu Ala Lys Val Asp Asp Leu Pro Pro Ala Leu Arg Lys Pro 
            260                 265                 270         


Pro Ile Ser Val Ser Gln His Glu Ser His Gln Ala Ile Ser His Leu 
        275                 280                 285             


Pro Thr Gly Gln Pro Leu Ser Pro Asn Met Pro Pro Asp Ser His Ile 
    290                 295                 300                 


Asn His Asn Gly Asn Pro Gly Thr Ser Lys Gln Asn Pro Ser Ser Pro 
305                 310                 315                 320 


Leu Gln Arg Leu Ile Pro Gly Ser Asn Leu Asp Ser Glu Pro Arg Ile 
                325                 330                 335     


Gln Thr Asp Ile Leu Lys Gln Ala Thr Lys Asp Arg Val Ser Asp Phe 
            340                 345                 350         


His Lys Leu Lys Gln Ser Arg Phe Phe Asp Glu Asn Glu Ser Pro Val 
        355                 360                 365             


Asp Pro Gln His Gly Ser Lys Leu Ala Asp Tyr Asn Gly Asp Asp Gly 
    370                 375                 380                 


Asn Val Gly Glu Tyr Glu Ala Asp Lys Gln Ala Glu Leu Ala Tyr Asn 
385                 390                 395                 400 


Glu Glu Glu Asp Gly Asp Gly Gly Glu Glu Asp Val Gln Asp Asp Glu 
                405                 410                 415     


Glu Arg Glu Leu Gln Met Asp Pro Ala Asp Tyr Gly Lys Gln His Phe 
            420                 425                 430         


Asn Asp Val Leu 
        435     


<210>  3218
<211>  89
<212>  PRT
<213>  homo sapiens

<400>  3218

Met Cys Gln Lys Glu Val Met Glu Gln Ser Ala Gly Ile Met Tyr Arg 
1               5                   10                  15      


Lys Ser Cys Ala Ser Ser Ala Ala Cys Leu Ile Ala Ser Ala Gly Tyr 
            20                  25                  30          


Gln Ser Phe Cys Ser Pro Gly Lys Leu Asn Ser Val Cys Ile Ser Cys 
        35                  40                  45              


Cys Asn Thr Pro Leu Cys Asn Gly Pro Arg Pro Lys Lys Arg Gly Ser 
    50                  55                  60                  


Ser Ala Ser Ala Leu Arg Pro Gly Leu Arg Thr Thr Ile Leu Phe Leu 
65                  70                  75                  80  


Lys Leu Ala Leu Phe Ser Ala His Cys 
                85                  


<210>  3219
<211>  141
<212>  PRT
<213>  homo sapiens

<400>  3219

Met Trp Val Leu Gly Ile Ala Ala Thr Phe Cys Gly Leu Phe Leu Leu 
1               5                   10                  15      


Pro Gly Phe Ala Leu Gln Ile Gln Cys Tyr Gln Cys Glu Glu Phe Gln 
            20                  25                  30          


Leu Asn Asn Asp Cys Ser Ser Pro Glu Phe Ile Val Asn Cys Thr Val 
        35                  40                  45              


Asn Val Gln Asp Met Cys Gln Lys Glu Val Met Glu Gln Ser Ala Gly 
    50                  55                  60                  


Ile Met Tyr Arg Lys Ser Cys Ala Ser Ser Ala Ala Cys Leu Ile Ala 
65                  70                  75                  80  


Ser Ala Gly Tyr Gln Ser Phe Cys Ser Pro Gly Lys Leu Asn Ser Val 
                85                  90                  95      


Cys Ile Ser Cys Cys Asn Thr Pro Leu Cys Asn Gly Pro Arg Pro Lys 
            100                 105                 110         


Lys Arg Gly Ser Ser Ala Ser Ala Leu Arg Pro Gly Leu Arg Thr Thr 
        115                 120                 125             


Ile Leu Phe Leu Lys Leu Ala Leu Phe Ser Ala His Cys 
    130                 135                 140     


<210>  3220
<211>  205
<212>  PRT
<213>  homo sapiens

<400>  3220

Met Ala Leu Gln Leu Ser Arg Glu Gln Gly Ile Thr Leu Arg Gly Ser 
1               5                   10                  15      


Ala Glu Ile Val Ala Glu Phe Phe Ser Phe Gly Ile Asn Ser Ile Leu 
            20                  25                  30          


Tyr Gln Arg Gly Ile Tyr Pro Ser Glu Thr Phe Thr Arg Val Gln Lys 
        35                  40                  45              


Tyr Gly Leu Thr Leu Leu Val Thr Thr Asp Leu Glu Leu Ile Lys Tyr 
    50                  55                  60                  


Leu Asn Asn Val Val Glu Gln Leu Lys Asp Trp Leu Tyr Lys Cys Ser 
65                  70                  75                  80  


Val Gln Lys Leu Val Val Val Ile Ser Asn Ile Glu Ser Gly Glu Val 
                85                  90                  95      


Leu Glu Arg Trp Gln Phe Asp Ile Glu Cys Asp Lys Thr Ala Lys Asp 
            100                 105                 110         


Asp Ser Ala Pro Arg Glu Lys Ser Gln Lys Ala Ile Gln Asp Glu Ile 
        115                 120                 125             


Arg Ser Val Ile Arg Gln Ile Thr Ala Thr Val Thr Phe Leu Pro Leu 
    130                 135                 140                 


Leu Glu Val Ser Cys Ser Phe Asp Leu Leu Ile Tyr Thr Asp Lys Asp 
145                 150                 155                 160 


Leu Val Val Pro Glu Lys Trp Glu Glu Ser Gly Pro Gln Phe Ile Thr 
                165                 170                 175     


Asn Ser Glu Glu Val Arg Leu Arg Ser Phe Thr Thr Thr Ile His Lys 
            180                 185                 190         


Val Asn Ser Met Val Ala Tyr Lys Ile Pro Val Asn Asp 
        195                 200                 205 


<210>  3221
<211>  403
<212>  PRT
<213>  homo sapiens

<400>  3221

Met Ala Ser Glu Leu Ala Met Ser Asn Ser Asp Leu Pro Thr Ser Pro 
1               5                   10                  15      


Leu Ala Met Glu Tyr Val Asn Asp Phe Asp Leu Met Lys Phe Glu Val 
            20                  25                  30          


Lys Lys Glu Pro Val Glu Thr Asp Arg Ile Ile Ser Gln Cys Gly Arg 
        35                  40                  45              


Leu Ile Ala Gly Gly Ser Leu Ser Ser Thr Pro Met Ser Thr Pro Cys 
    50                  55                  60                  


Ser Ser Val Pro Pro Ser Pro Ser Phe Ser Ala Pro Ser Pro Gly Ser 
65                  70                  75                  80  


Gly Ser Glu Gln Lys Ala His Leu Glu Asp Tyr Tyr Trp Met Thr Gly 
                85                  90                  95      


Tyr Pro Gln Gln Leu Asn Pro Glu Ala Leu Gly Phe Ser Pro Glu Asp 
            100                 105                 110         


Ala Val Glu Ala Leu Ile Ser Asn Ser His Gln Leu Gln Gly Gly Phe 
        115                 120                 125             


Asp Gly Tyr Ala Arg Gly Ala Gln Gln Leu Ala Ala Ala Ala Gly Ala 
    130                 135                 140                 


Gly Ala Gly Ala Ser Leu Gly Gly Ser Gly Glu Glu Met Gly Pro Ala 
145                 150                 155                 160 


Ala Ala Val Val Ser Ala Val Ile Ala Ala Ala Ala Ala Gln Ser Gly 
                165                 170                 175     


Ala Gly Pro His Tyr His His His His His His Ala Ala Gly His His 
            180                 185                 190         


His His Pro Thr Ala Gly Ala Pro Gly Ala Ala Gly Ser Ala Ala Ala 
        195                 200                 205             


Ser Ala Gly Gly Ala Gly Gly Ala Gly Gly Gly Gly Pro Ala Ser Ala 
    210                 215                 220                 


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Ala 
225                 230                 235                 240 


Gly Ala Gly Gly Ala Leu His Pro His His Ala Ala Gly Gly Leu His 
                245                 250                 255     


Phe Asp Asp Arg Phe Ser Asp Glu Gln Leu Val Thr Met Ser Val Arg 
            260                 265                 270         


Glu Leu Asn Arg Gln Leu Arg Gly Val Ser Lys Glu Glu Val Ile Arg 
        275                 280                 285             


Leu Lys Gln Lys Arg Arg Thr Leu Lys Asn Arg Gly Tyr Ala Gln Ser 
    290                 295                 300                 


Cys Arg Phe Lys Arg Val Gln Gln Arg His Val Leu Glu Ser Glu Lys 
305                 310                 315                 320 


Asn Gln Leu Leu Gln Gln Val Asp His Leu Lys Gln Glu Ile Ser Arg 
                325                 330                 335     


Leu Val Arg Glu Arg Asp Ala Tyr Lys Glu Lys Tyr Glu Lys Leu Val 
            340                 345                 350         


Ser Ser Gly Phe Arg Glu Asn Gly Ser Ser Ser Asp Asn Pro Ser Ser 
        355                 360                 365             


Pro Glu Phe Phe Ile Thr Glu Pro Thr Arg Lys Leu Glu Pro Ser Val 
    370                 375                 380                 


Gly Tyr Ala Thr Phe Trp Lys Pro Gln His Arg Val Leu Thr Ser Val 
385                 390                 395                 400 


Phe Thr Lys 
            


<210>  3222
<211>  229
<212>  PRT
<213>  homo sapiens

<400>  3222

Met Gly Leu Leu Arg Ile Met Met Pro Pro Lys Leu Gln Leu Leu Ala 
1               5                   10                  15      


Val Val Ala Phe Ala Val Ala Met Leu Phe Leu Glu Asn Gln Ile Gln 
            20                  25                  30          


Lys Leu Glu Glu Ser Arg Ser Lys Leu Glu Arg Ala Ile Ala Arg His 
        35                  40                  45              


Glu Val Arg Glu Ile Glu Gln Arg His Thr Met Asp Gly Pro Arg Gln 
    50                  55                  60                  


Asp Ala Thr Leu Asp Glu Glu Glu Asp Met Val Ile Ile Tyr Asn Arg 
65                  70                  75                  80  


Val Pro Lys Thr Ala Ser Thr Ser Phe Thr Asn Ile Ala Tyr Asp Leu 
                85                  90                  95      


Cys Ala Lys Asn Lys Tyr His Val Leu His Ile Asn Thr Thr Lys Asn 
            100                 105                 110         


Asn Pro Val Met Ser Leu Gln Asp Gln Val Arg Phe Val Lys Asn Ile 
        115                 120                 125             


Thr Ser Trp Lys Glu Met Lys Pro Gly Phe Tyr His Gly His Val Ser 
    130                 135                 140                 


Tyr Leu Asp Phe Ala Lys Phe Gly Val Lys Lys Lys Pro Ile Tyr Ile 
145                 150                 155                 160 


Asn Val Ile Arg Asp Pro Ile Glu Arg Leu Val Ser Tyr Tyr Tyr Phe 
                165                 170                 175     


Leu Arg Phe Gly Asp Asp Tyr Arg Pro Gly Leu Arg Arg Arg Lys Gln 
            180                 185                 190         


Gly Asp Lys Lys Thr Phe Asp Glu Cys Val Ala Glu Gly Gly Ser Asp 
        195                 200                 205             


Cys Ala Pro Glu Lys Leu Trp Leu Gln Ile Pro Phe Phe Cys Gly His 
    210                 215                 220                 


Ser Ser Glu Cys Trp 
225                 


<210>  3223
<211>  847
<212>  PRT
<213>  homo sapiens

<400>  3223

Met Ser Gln Arg Gln Gly Lys Glu Ala Tyr Pro Thr Pro Thr Lys Asp 
1               5                   10                  15      


Leu His Gln Pro Ser Leu Ser Pro Ala Ser Pro His Ser Gln Gly Phe 
            20                  25                  30          


Glu Arg Gly Lys Glu Asp Ile Ser Gln Asn Lys Asp Glu Ser Ser Leu 
        35                  40                  45              


Ser Met Ser Lys Ser Lys Ser Glu Ser Lys Leu Tyr Asn Gly Ser Glu 
    50                  55                  60                  


Lys Asp Ser Ser Thr Ser Ser Lys Leu Thr Lys Lys Glu Ser Leu Lys 
65                  70                  75                  80  


Val Gln Lys Lys Asn Tyr Arg Glu Glu Lys Lys Arg Ala Thr Lys Glu 
                85                  90                  95      


Leu Leu Ser Thr Ile Thr Asp Pro Ser Val Ile Val Met Ala Asp Trp 
            100                 105                 110         


Leu Lys Ile Arg Gly Thr Leu Lys Ser Trp Thr Lys Leu Trp Cys Val 
        115                 120                 125             


Leu Lys Pro Gly Val Leu Leu Ile Tyr Lys Thr Gln Lys Asn Gly Gln 
    130                 135                 140                 


Trp Val Gly Thr Val Leu Leu Asn Ala Cys Glu Ile Ile Glu Arg Pro 
145                 150                 155                 160 


Ser Lys Lys Asp Gly Phe Cys Phe Lys Leu Phe His Pro Leu Glu Gln 
                165                 170                 175     


Ser Ile Trp Ala Val Lys Gly Pro Lys Gly Glu Ala Val Gly Ser Ile 
            180                 185                 190         


Thr Gln Pro Leu Pro Ser Ser Tyr Leu Ile Ile Arg Ala Thr Ser Glu 
        195                 200                 205             


Ser Asp Gly Arg Cys Trp Met Asp Ala Leu Glu Leu Ala Leu Lys Cys 
    210                 215                 220                 


Ser Ser Leu Leu Lys Arg Thr Met Ile Arg Glu Gly Lys Glu His Asp 
225                 230                 235                 240 


Leu Ser Val Ser Ser Asp Ser Thr His Val Thr Phe Tyr Gly Leu Leu 
                245                 250                 255     


Arg Ala Asn Asn Leu His Ser Gly Asp Asn Phe Gln Leu Asn Asp Ser 
            260                 265                 270         


Glu Ile Glu Arg Gln His Phe Lys Asp Gln Asp Met Tyr Ser Asp Lys 
        275                 280                 285             


Ser Asp Lys Glu Asn Asp Gln Glu His Asp Glu Ser Asp Asn Glu Val 
    290                 295                 300                 


Met Gly Lys Ser Glu Glu Ser Asp Thr Asp Thr Ser Glu Arg Gln Asp 
305                 310                 315                 320 


Asp Ser Tyr Ile Glu Pro Glu Pro Val Glu Pro Leu Lys Glu Thr Thr 
                325                 330                 335     


Tyr Thr Glu Gln Ser His Glu Glu Leu Gly Glu Ala Gly Glu Ala Ser 
            340                 345                 350         


Gln Thr Glu Thr Val Ser Glu Glu Asn Lys Ser Leu Ile Trp Thr Leu 
        355                 360                 365             


Leu Lys Gln Val Arg Pro Gly Met Asp Leu Ser Lys Val Val Leu Pro 
    370                 375                 380                 


Thr Phe Ile Leu Glu Pro Arg Ser Phe Leu Asp Lys Leu Ser Asp Tyr 
385                 390                 395                 400 


Tyr Tyr His Ala Asp Phe Leu Ser Glu Ala Ala Leu Glu Glu Asn Pro 
                405                 410                 415     


Tyr Phe Arg Leu Lys Lys Val Val Lys Trp Tyr Leu Ser Gly Phe Tyr 
            420                 425                 430         


Lys Lys Pro Lys Gly Leu Lys Lys Pro Tyr Asn Pro Ile Leu Gly Glu 
        435                 440                 445             


Thr Phe Arg Cys Leu Trp Ile His Pro Arg Thr Asn Ser Lys Thr Phe 
    450                 455                 460                 


Tyr Ile Ala Glu Gln Val Ser His His Pro Pro Ile Ser Ala Phe Tyr 
465                 470                 475                 480 


Val Ser Asn Arg Lys Asp Gly Phe Cys Leu Ser Gly Ser Ile Leu Ala 
                485                 490                 495     


Lys Ser Lys Phe Tyr Gly Asn Ser Leu Ser Ala Ile Leu Glu Gly Glu 
            500                 505                 510         


Ala Arg Leu Thr Phe Leu Asn Arg Gly Glu Asp Tyr Val Met Thr Met 
        515                 520                 525             


Pro Tyr Ala His Cys Lys Gly Ile Leu Tyr Gly Thr Met Thr Leu Glu 
    530                 535                 540                 


Leu Gly Gly Thr Val Asn Ile Thr Cys Gln Lys Thr Gly Tyr Ser Ala 
545                 550                 555                 560 


Ile Leu Glu Phe Lys Leu Lys Pro Phe Leu Gly Ser Ser Asp Cys Val 
                565                 570                 575     


Asn Gln Ile Ser Gly Lys Leu Lys Leu Gly Lys Glu Val Leu Ala Thr 
            580                 585                 590         


Leu Glu Gly His Trp Asp Ser Glu Val Phe Ile Thr Asp Lys Lys Thr 
        595                 600                 605             


Asp Asn Ser Glu Val Phe Trp Asn Pro Thr Pro Asp Ile Lys Gln Trp 
    610                 615                 620                 


Arg Leu Ile Arg His Thr Val Lys Phe Glu Glu Gln Gly Asp Phe Glu 
625                 630                 635                 640 


Ser Glu Lys Leu Trp Gln Arg Val Thr Arg Ala Ile Asn Ala Lys Asp 
                645                 650                 655     


Gln Thr Glu Ala Thr Gln Glu Lys Tyr Val Leu Glu Glu Ala Gln Arg 
            660                 665                 670         


Gln Ala Ala Arg Asp Arg Lys Thr Lys Asn Glu Glu Trp Ser Cys Lys 
        675                 680                 685             


Leu Phe Glu Leu Asp Pro Leu Thr Gly Glu Trp His Tyr Lys Phe Ala 
    690                 695                 700                 


Asp Thr Arg Pro Trp Asp Pro Leu Asn Asp Met Ile Gln Phe Glu Lys 
705                 710                 715                 720 


Asp Gly Val Ile Gln Thr Lys Val Lys His Arg Thr Pro Met Val Ser 
                725                 730                 735     


Val Pro Lys Met Lys His Lys Pro Thr Arg Gln Gln Lys Lys Val Ala 
            740                 745                 750         


Lys Gly Tyr Ser Ser Pro Glu Pro Asp Ile Gln Asp Ser Ser Gly Ser 
        755                 760                 765             


Glu Ala Gln Ser Val Lys Pro Ser Thr Arg Arg Lys Lys Gly Ile Glu 
    770                 775                 780                 


Leu Gly Asp Ile Gln Ser Ser Ile Glu Ser Ile Lys Gln Thr Gln Glu 
785                 790                 795                 800 


Glu Ile Lys Arg Asn Ile Met Ala Leu Arg Asn His Leu Val Ser Ser 
                805                 810                 815     


Thr Pro Ala Thr Asp Tyr Phe Leu Gln Gln Lys Asp Tyr Phe Ile Ile 
            820                 825                 830         


Phe Leu Leu Ile Leu Leu Gln Val Ile Ile Asn Phe Met Phe Lys 
        835                 840                 845         


<210>  3224
<211>  456
<212>  PRT
<213>  homo sapiens

<400>  3224

Met Ala Asp Gly Gly Ser Glu Arg Ala Asp Gly Arg Ile Val Lys Met 
1               5                   10                  15      


Glu Val Asp Tyr Ser Ala Thr Val Asp Gln Arg Leu Pro Glu Cys Ala 
            20                  25                  30          


Lys Leu Ala Lys Glu Gly Arg Leu Gln Glu Val Ile Glu Thr Leu Leu 
        35                  40                  45              


Ser Leu Glu Lys Gln Thr Arg Thr Ala Ser Asp Met Val Ser Thr Ser 
    50                  55                  60                  


Arg Ile Leu Val Ala Val Val Lys Met Cys Tyr Glu Ala Lys Glu Trp 
65                  70                  75                  80  


Asp Leu Leu Asn Glu Asn Ile Met Leu Leu Ser Lys Arg Arg Ser Gln 
                85                  90                  95      


Leu Lys Gln Ala Val Ala Lys Met Val Gln Gln Cys Cys Thr Tyr Val 
            100                 105                 110         


Glu Glu Ile Thr Asp Leu Pro Ile Lys Leu Arg Leu Ile Asp Thr Leu 
        115                 120                 125             


Arg Met Val Thr Glu Gly Lys Ile Tyr Val Glu Ile Glu Arg Ala Arg 
    130                 135                 140                 


Leu Thr Lys Thr Leu Ala Thr Ile Lys Glu Gln Asn Gly Asp Val Lys 
145                 150                 155                 160 


Glu Ala Ala Ser Ile Leu Gln Glu Leu Gln Val Glu Thr Tyr Gly Ser 
                165                 170                 175     


Met Glu Lys Lys Glu Arg Val Glu Phe Ile Leu Glu Gln Met Arg Leu 
            180                 185                 190         


Cys Leu Ala Val Lys Asp Tyr Ile Arg Thr Gln Ile Ile Ser Lys Lys 
        195                 200                 205             


Ile Asn Thr Lys Phe Phe Gln Glu Glu Asn Thr Glu Lys Leu Lys Leu 
    210                 215                 220                 


Lys Tyr Tyr Asn Leu Met Ile Gln Leu Asp Gln His Glu Gly Ser Tyr 
225                 230                 235                 240 


Leu Ser Ile Cys Lys His Tyr Arg Ala Ile Tyr Asp Thr Pro Cys Ile 
                245                 250                 255     


Gln Ala Glu Ser Glu Lys Trp Gln Gln Ala Leu Lys Ser Val Val Leu 
            260                 265                 270         


Tyr Val Ile Leu Ala Pro Phe Asp Asn Glu Gln Ser Asp Leu Val His 
        275                 280                 285             


Arg Ile Ser Gly Asp Lys Lys Leu Glu Glu Ile Pro Lys Tyr Lys Asp 
    290                 295                 300                 


Leu Leu Lys Leu Phe Thr Thr Met Glu Leu Met Arg Trp Ser Thr Leu 
305                 310                 315                 320 


Val Glu Asp Tyr Gly Met Glu Leu Arg Lys Gly Ser Leu Glu Ser Pro 
                325                 330                 335     


Ala Thr Asp Val Phe Gly Ser Thr Glu Glu Gly Glu Lys Arg Trp Lys 
            340                 345                 350         


Asp Leu Lys Asn Arg Val Val Glu His Asn Ile Arg Ile Met Ala Lys 
        355                 360                 365             


Tyr Tyr Thr Arg Ile Thr Met Lys Arg Met Ala Gln Leu Leu Asp Leu 
    370                 375                 380                 


Ser Val Asp Glu Ser Glu Ala Phe Leu Ser Asn Leu Val Val Asn Lys 
385                 390                 395                 400 


Thr Ile Phe Ala Lys Val Asp Arg Leu Ala Gly Ile Ile Asn Phe Gln 
                405                 410                 415     


Arg Pro Lys Asp Pro Asn Asn Leu Leu Asn Asp Trp Ser Gln Lys Leu 
            420                 425                 430         


Asn Ser Leu Met Ser Leu Val Asn Lys Thr Thr His Leu Ile Ala Lys 
        435                 440                 445             


Glu Glu Met Ile His Asn Leu Gln 
    450                 455     


<210>  3225
<211>  323
<212>  PRT
<213>  homo sapiens

<400>  3225

Met Thr Ser Gly Asn Gly Asn Ser Ala Ser Ser Ile Ala Gly Thr Ala 
1               5                   10                  15      


Pro Gln Asn Gly Glu Asn Lys Pro Pro Gln Ala Ile Val Lys Pro Gln 
            20                  25                  30          


Ile Leu Thr His Val Ile Glu Gly Phe Val Ile Gln Glu Gly Ala Glu 
        35                  40                  45              


Pro Phe Pro Val Gly Arg Ser Ser Leu Leu Val Gly Asn Leu Lys Lys 
    50                  55                  60                  


Lys Tyr Ala Gln Gly Phe Leu Pro Glu Lys Leu Pro Gln Gln Asp His 
65                  70                  75                  80  


Thr Thr Thr Thr Asp Ser Glu Met Glu Glu Pro Tyr Leu Gln Glu Ser 
                85                  90                  95      


Lys Glu Glu Gly Ala Pro Leu Lys Leu Lys Cys Glu Leu Cys Gly Arg 
            100                 105                 110         


Val Asp Phe Ala Tyr Lys Phe Lys Arg Ser Lys Arg Phe Cys Ser Met 
        115                 120                 125             


Ala Cys Ala Lys Arg Tyr Asn Val Gly Cys Thr Lys Arg Val Gly Leu 
    130                 135                 140                 


Phe His Ser Asp Arg Ser Lys Leu Gln Lys Ala Gly Ala Ala Thr His 
145                 150                 155                 160 


Asn Arg Arg Arg Ala Ser Lys Ala Ser Leu Pro Pro Leu Thr Lys Asp 
                165                 170                 175     


Thr Lys Lys Gln Pro Thr Gly Thr Val Pro Leu Ser Val Thr Ala Ala 
            180                 185                 190         


Leu Gln Leu Thr His Ser Gln Glu Asp Ser Ser Arg Cys Ser Asp Asn 
        195                 200                 205             


Ser Ser Tyr Glu Glu Pro Leu Ser Pro Ile Ser Ala Ser Ser Ser Thr 
    210                 215                 220                 


Ser Arg Arg Arg Gln Gly Gln Arg Asp Leu Glu Leu Pro Asp Met His 
225                 230                 235                 240 


Met Arg Asp Leu Val Gly Met Gly His His Phe Leu Pro Ser Glu Pro 
                245                 250                 255     


Thr Lys Trp Asn Val Glu Asp Val Tyr Glu Phe Ile Arg Ser Leu Pro 
            260                 265                 270         


Gly Cys Gln Glu Ile Ala Glu Glu Phe Arg Ala Gln Glu Ile Asp Gly 
        275                 280                 285             


Gln Ala Leu Leu Leu Leu Lys Glu Asp His Leu Met Ser Ala Met Asn 
    290                 295                 300                 


Ile Lys Leu Gly Pro Ala Leu Lys Ile Tyr Ala Arg Ile Ser Met Leu 
305                 310                 315                 320 


Lys Asp Ser 
            


<210>  3226
<211>  365
<212>  PRT
<213>  homo sapiens

<400>  3226

Met Ser Ser Ser Val Glu Gln Lys Lys Gly Pro Thr Arg Gln Arg Lys 
1               5                   10                  15      


Cys Gly Phe Cys Lys Ser Asn Arg Asp Lys Glu Cys Gly Gln Leu Leu 
            20                  25                  30          


Ile Ser Glu Asn Gln Lys Val Ala Ala His His Lys Cys Met Leu Phe 
        35                  40                  45              


Ser Ser Ala Leu Val Ser Ser His Ser Asp Asn Glu Ser Leu Gly Gly 
    50                  55                  60                  


Phe Ser Ile Glu Asp Val Gln Lys Glu Ile Lys Arg Gly Thr Lys Leu 
65                  70                  75                  80  


Met Cys Ser Leu Cys His Cys Pro Gly Ala Thr Ile Gly Cys Asp Val 
                85                  90                  95      


Lys Thr Cys His Arg Thr Tyr His Tyr His Cys Ala Leu His Asp Lys 
            100                 105                 110         


Ala Gln Ile Arg Glu Lys Pro Ser Gln Gly Ile Tyr Met Val Tyr Cys 
        115                 120                 125             


Arg Lys His Lys Lys Thr Ala His Asn Ser Glu Ala Asp Leu Glu Glu 
    130                 135                 140                 


Ser Phe Asn Glu His Glu Leu Glu Pro Ser Ser Pro Lys Ser Lys Lys 
145                 150                 155                 160 


Lys Ser Arg Lys Gly Arg Pro Arg Lys Thr Asn Phe Lys Gly Leu Ser 
                165                 170                 175     


Glu Asp Thr Arg Ser Thr Ser Ser His Gly Thr Asp Glu Met Glu Ser 
            180                 185                 190         


Ser Ser Tyr Arg Asp Arg Ser Pro His Arg Ser Ser Pro Ser Asp Thr 
        195                 200                 205             


Arg Pro Lys Cys Gly Phe Cys His Val Gly Glu Glu Glu Asn Glu Ala 
    210                 215                 220                 


Arg Gly Lys Leu His Ile Phe Asn Ala Lys Lys Ala Ala Ala His Tyr 
225                 230                 235                 240 


Lys Cys Met Leu Phe Ser Ser Gly Thr Val Gln Leu Thr Thr Thr Ser 
                245                 250                 255     


Arg Ala Glu Phe Gly Asp Phe Asp Ile Lys Thr Val Leu Gln Glu Ile 
            260                 265                 270         


Lys Arg Gly Lys Arg Met Lys Cys Thr Leu Cys Ser Gln Pro Gly Ala 
        275                 280                 285             


Thr Ile Gly Cys Glu Ile Lys Ala Cys Val Lys Thr Tyr His Tyr His 
    290                 295                 300                 


Cys Gly Val Gln Asp Lys Ala Lys Tyr Ile Glu Asn Met Ser Arg Gly 
305                 310                 315                 320 


Ile Tyr Lys Leu Tyr Cys Lys Asn His Ser Gly Asn Asp Glu Arg Asp 
                325                 330                 335     


Glu Glu Asp Glu Glu Arg Glu Ser Lys Ser Arg Gly Lys Val Glu Ile 
            340                 345                 350         


Asp Gln Gln Gln Leu Thr Gln Gln Gln Leu Asn Gly Asn 
        355                 360                 365 


<210>  3227
<211>  113
<212>  PRT
<213>  homo sapiens

<400>  3227

Met Ala Asp Val Glu Asp Gly Glu Glu Thr Cys Ala Leu Ala Ser His 
1               5                   10                  15      


Ser Gly Ser Ser Gly Ser Lys Ser Gly Gly Asp Lys Met Phe Ser Leu 
            20                  25                  30          


Lys Lys Trp Asn Ala Val Ala Met Trp Ser Trp Asp Val Glu Cys Asp 
        35                  40                  45              


Thr Cys Ala Ile Cys Arg Val Gln Val Met Asp Ala Cys Leu Arg Cys 
    50                  55                  60                  


Gln Ala Glu Asn Lys Gln Glu Asp Cys Val Val Val Trp Gly Glu Cys 
65                  70                  75                  80  


Asn His Ser Phe His Asn Cys Cys Met Ser Leu Trp Val Lys Gln Asn 
                85                  90                  95      


Asn Arg Cys Pro Leu Cys Gln Gln Asp Trp Val Val Gln Arg Ile Gly 
            100                 105                 110         


Lys 
    


<210>  3228
<211>  452
<212>  PRT
<213>  homo sapiens

<400>  3228

Met Leu Cys Gly Arg Pro Arg Ser Ser Ser Asp Asn Arg Asn Phe Leu 
1               5                   10                  15      


Arg Glu Arg Ala Gly Leu Ser Ser Ala Ala Val Gln Thr Arg Ile Gly 
            20                  25                  30          


Asn Ser Ala Ala Ser Arg Arg Ser Pro Ala Ala Arg Pro Pro Val Pro 
        35                  40                  45              


Ala Pro Pro Ala Leu Pro Arg Gly Arg Pro Gly Thr Glu Gly Ser Thr 
    50                  55                  60                  


Ser Leu Ser Ala Pro Ala Val Leu Val Val Ala Val Ala Val Val Val 
65                  70                  75                  80  


Val Val Val Ser Ala Val Ala Trp Ala Met Ala Asn Tyr Ile His Val 
                85                  90                  95      


Pro Pro Gly Ser Pro Glu Val Pro Lys Leu Asn Val Thr Val Gln Asp 
            100                 105                 110         


Gln Glu Glu His Arg Cys Arg Glu Gly Ala Leu Ser Leu Leu Gln His 
        115                 120                 125             


Leu Arg Pro His Trp Asp Pro Gln Glu Val Thr Leu Gln Leu Phe Thr 
    130                 135                 140                 


Asp Gly Ile Thr Asn Lys Leu Ile Gly Cys Tyr Val Gly Asn Thr Met 
145                 150                 155                 160 


Glu Asp Val Val Leu Val Arg Ile Tyr Gly Asn Lys Thr Glu Leu Leu 
                165                 170                 175     


Val Asp Arg Asp Glu Glu Val Lys Ser Phe Arg Val Leu Gln Ala His 
            180                 185                 190         


Gly Cys Ala Pro Gln Leu Tyr Cys Thr Phe Asn Asn Gly Leu Cys Tyr 
        195                 200                 205             


Glu Phe Ile Gln Gly Glu Ala Leu Asp Pro Lys His Val Cys Asn Pro 
    210                 215                 220                 


Ala Ile Phe Arg Leu Ile Ala Arg Gln Leu Ala Lys Ile His Ala Ile 
225                 230                 235                 240 


His Ala His Asn Gly Trp Ile Pro Lys Ser Asn Leu Trp Leu Lys Met 
                245                 250                 255     


Gly Lys Tyr Phe Ser Leu Ile Pro Thr Gly Phe Ala Asp Glu Asp Ile 
            260                 265                 270         


Asn Lys Arg Phe Leu Ser Asp Ile Pro Ser Ser Gln Ile Leu Gln Glu 
        275                 280                 285             


Glu Met Thr Trp Met Lys Glu Ile Leu Ser Asn Leu Gly Ser Pro Val 
    290                 295                 300                 


Val Leu Cys His Asn Asp Leu Leu Cys Lys Asn Ile Ile Tyr Asn Glu 
305                 310                 315                 320 


Lys Gln Gly Asp Val Gln Phe Ile Asp Tyr Glu Tyr Ser Gly Tyr Asn 
                325                 330                 335     


Tyr Leu Ala Tyr Asp Ile Gly Asn His Phe Asn Glu Phe Ala Gly Val 
            340                 345                 350         


Ser Asp Val Asp Tyr Ser Leu Tyr Pro Asp Arg Glu Leu Gln Ser Gln 
        355                 360                 365             


Trp Leu Arg Ala Tyr Leu Glu Ala Tyr Lys Glu Phe Lys Gly Phe Gly 
    370                 375                 380                 


Thr Glu Val Thr Glu Lys Glu Val Glu Ile Leu Phe Ile Gln Val Asn 
385                 390                 395                 400 


Gln Phe Ala Leu Ala Ser His Phe Phe Trp Gly Leu Trp Ala Leu Ile 
                405                 410                 415     


Gln Ala Lys Tyr Ser Thr Ile Glu Phe Asp Phe Leu Gly Tyr Ala Ile 
            420                 425                 430         


Val Arg Phe Asn Gln Tyr Phe Lys Met Lys Pro Glu Val Thr Ala Leu 
        435                 440                 445             


Lys Val Pro Glu 
    450         


<210>  3229
<211>  369
<212>  PRT
<213>  homo sapiens

<400>  3229

Met Phe Cys Thr Ser Gly Gly Asn Ser Ala Ser Val Met Ser Met Arg 
1               5                   10                  15      


Pro Val Pro Gly Ser Leu Ser Ser Leu Leu His Leu His Asn Arg Gln 
            20                  25                  30          


Arg Gln Pro Met Pro Ala Ser Met Pro Gly Thr Leu Pro Asn Pro Thr 
        35                  40                  45              


Met Pro Gly Ser Ser Ala Val Leu Met Pro Met Glu Arg Gln Met Ser 
    50                  55                  60                  


Val Asn Ser Ser Ile Met Gly Met Gln Gly Pro Asn Leu Ser Asn Pro 
65                  70                  75                  80  


Cys Ala Ser Pro Gln Val Gln Pro Met His Ser Glu Ala Lys Met Arg 
                85                  90                  95      


Leu Lys Ala Ala Leu Thr His His Pro Ala Ala Met Ser Asn Gly Asn 
            100                 105                 110         


Met Asn Thr Met Gly His Met Met Glu Met Met Gly Ser Arg Gln Asp 
        115                 120                 125             


Gln Thr Pro His His His Met His Ser His Pro His Gln His Gln Thr 
    130                 135                 140                 


Leu Pro Pro His His Pro Tyr Pro His Gln His Gln His Pro Ala His 
145                 150                 155                 160 


His Pro His Pro Gln Pro His His Gln Gln Asn His Pro His His His 
                165                 170                 175     


Ser His Ser His Leu His Ala His Pro Ala His His Gln Thr Ser Pro 
            180                 185                 190         


His Pro Pro Leu His Thr Gly Asn Gln Ala Gln Val Ser Pro Ala Thr 
        195                 200                 205             


Gln Gln Met Gln Pro Thr Gln Thr Ile Gln Pro Pro Gln Pro Thr Gly 
    210                 215                 220                 


Gly Arg Arg Arg Arg Val Val Asp Glu Asp Pro Asp Glu Arg Arg Arg 
225                 230                 235                 240 


Lys Phe Leu Glu Arg Asn Arg Ala Ala Ala Thr Arg Cys Arg Gln Lys 
                245                 250                 255     


Arg Lys Val Trp Val Met Ser Leu Glu Lys Lys Ala Glu Glu Leu Thr 
            260                 265                 270         


Gln Thr Asn Met Gln Leu Gln Asn Glu Val Ser Met Leu Lys Asn Glu 
        275                 280                 285             


Val Ala Gln Leu Lys Gln Leu Leu Leu Thr His Lys Asp Cys Pro Ile 
    290                 295                 300                 


Thr Ala Met Gln Lys Glu Ser Gln Gly Tyr Leu Ser Pro Glu Ser Ser 
305                 310                 315                 320 


Pro Pro Ala Ser Pro Val Pro Ala Cys Ser Gln Gln Gln Val Ile Gln 
                325                 330                 335     


His Asn Thr Ile Thr Thr Ser Ser Ser Val Ser Glu Val Val Gly Ser 
            340                 345                 350         


Ser Thr Leu Ser Gln Leu Thr Thr His Arg Thr Asp Leu Asn Pro Ile 
        355                 360                 365             


Leu 
    


<210>  3230
<211>  152
<212>  PRT
<213>  homo sapiens

<400>  3230

Met Ser Val Pro Gly Pro Tyr Gln Ala Ala Thr Gly Pro Ser Ser Ala 
1               5                   10                  15      


Pro Ser Ala Pro Pro Ser Tyr Glu Glu Thr Val Ala Val Asn Ser Tyr 
            20                  25                  30          


Tyr Pro Thr Pro Pro Ala Pro Met Pro Gly Pro Thr Thr Gly Leu Val 
        35                  40                  45              


Thr Gly Pro Asp Gly Lys Gly Met Asn Pro Pro Ser Tyr Tyr Thr Gln 
    50                  55                  60                  


Pro Ala Pro Ile Pro Asn Asn Asn Pro Ile Thr Val Gln Thr Val Tyr 
65                  70                  75                  80  


Val Gln His Pro Ile Thr Phe Leu Asp Arg Pro Ile Gln Met Cys Cys 
                85                  90                  95      


Pro Ser Cys Asn Lys Met Ile Val Ser Gln Leu Ser Tyr Asn Ala Gly 
            100                 105                 110         


Ala Leu Thr Trp Leu Ser Cys Gly Ser Leu Cys Leu Leu Gly Gln Glu 
        115                 120                 125             


Cys Ser Gly Thr Ile Val Ala Leu Arg Ser Phe Asp Leu Leu Gly Ser 
    130                 135                 140                 


Cys Asn Pro Pro Ser Ser Ala Ser 
145                 150         


<210>  3231
<211>  2032
<212>  PRT
<213>  homo sapiens

<400>  3231

Met Gly Asp Asp Ser Glu Trp Leu Lys Leu Pro Val Asp Gln Lys Cys 
1               5                   10                  15      


Glu His Lys Leu Trp Lys Ala Arg Leu Ser Gly Tyr Glu Glu Ala Leu 
            20                  25                  30          


Lys Ile Phe Gln Lys Ile Lys Asp Glu Lys Ser Pro Glu Trp Ser Lys 
        35                  40                  45              


Phe Leu Gly Leu Ile Lys Lys Phe Val Thr Asp Ser Asn Ala Val Val 
    50                  55                  60                  


Gln Leu Lys Gly Leu Glu Ala Ala Leu Val Tyr Val Glu Asn Ala His 
65                  70                  75                  80  


Val Ala Gly Lys Thr Thr Gly Glu Val Val Ser Gly Val Val Ser Lys 
                85                  90                  95      


Val Phe Asn Gln Pro Lys Ala Lys Ala Lys Glu Leu Gly Ile Glu Ile 
            100                 105                 110         


Cys Leu Met Tyr Ile Glu Ile Glu Lys Gly Glu Ala Val Gln Glu Glu 
        115                 120                 125             


Leu Leu Lys Gly Leu Asp Asn Lys Asn Pro Lys Ile Ile Val Ala Cys 
    130                 135                 140                 


Ile Glu Thr Leu Arg Lys Ala Leu Ser Glu Phe Gly Ser Lys Ile Ile 
145                 150                 155                 160 


Leu Leu Lys Pro Ile Ile Lys Val Leu Pro Lys Leu Phe Glu Ser Arg 
                165                 170                 175     


Glu Lys Ala Val Arg Asp Glu Ala Lys Leu Ile Ala Val Glu Ile Tyr 
            180                 185                 190         


Arg Trp Ile Arg Asp Ala Leu Arg Pro Pro Leu Gln Asn Ile Asn Ser 
        195                 200                 205             


Val Gln Leu Lys Glu Leu Glu Glu Glu Trp Val Lys Leu Pro Thr Ser 
    210                 215                 220                 


Ala Pro Arg Pro Thr Arg Phe Leu Arg Ser Gln Gln Glu Leu Glu Ala 
225                 230                 235                 240 


Lys Leu Glu Gln Gln Gln Ser Ala Gly Gly Asp Ala Glu Gly Gly Gly 
                245                 250                 255     


Asp Asp Gly Asp Glu Val Pro Gln Ile Asp Ala Tyr Glu Leu Leu Glu 
            260                 265                 270         


Ala Val Glu Ile Leu Ser Lys Leu Pro Lys Asp Phe Tyr Asp Lys Ile 
        275                 280                 285             


Glu Ala Lys Lys Trp Gln Glu Arg Lys Glu Ala Leu Glu Ser Val Glu 
    290                 295                 300                 


Val Leu Ile Lys Asn Pro Lys Leu Glu Ala Gly Asp Tyr Ala Asp Leu 
305                 310                 315                 320 


Val Lys Ala Leu Lys Lys Val Val Gly Lys Asp Thr Asn Val Met Leu 
                325                 330                 335     


Val Ala Leu Ala Ala Lys Cys Leu Thr Gly Leu Ala Val Gly Leu Arg 
            340                 345                 350         


Lys Lys Phe Gly Gln Tyr Ala Gly His Val Val Pro Thr Ile Leu Glu 
        355                 360                 365             


Lys Phe Lys Glu Lys Lys Pro Gln Val Val Gln Ala Leu Gln Glu Ala 
    370                 375                 380                 


Ile Asp Ala Ile Phe Leu Thr Thr Thr Leu Gln Asn Ile Ser Glu Asp 
385                 390                 395                 400 


Val Leu Ala Val Met Asp Asn Lys Asn Pro Thr Ile Lys Gln Gln Thr 
                405                 410                 415     


Ser Leu Phe Ile Ala Arg Ser Phe Arg His Cys Thr Ala Ser Thr Leu 
            420                 425                 430         


Pro Lys Ser Leu Leu Lys Pro Phe Cys Ala Ala Leu Leu Lys His Ile 
        435                 440                 445             


Asn Asp Ser Ala Pro Glu Val Arg Asp Ala Ala Phe Glu Ala Leu Gly 
    450                 455                 460                 


Thr Ala Leu Lys Val Val Gly Glu Lys Ala Val Asn Pro Phe Leu Ala 
465                 470                 475                 480 


Asp Val Asp Lys Leu Lys Leu Asp Lys Ile Lys Glu Cys Ser Glu Lys 
                485                 490                 495     


Val Glu Leu Ile His Gly Lys Lys Ala Gly Leu Ala Ala Asp Lys Lys 
            500                 505                 510         


Glu Phe Lys Pro Leu Pro Gly Arg Thr Ala Ala Ser Gly Ala Ala Gly 
        515                 520                 525             


Asp Lys Asp Thr Lys Asp Ile Ser Ala Pro Lys Pro Gly Pro Leu Lys 
    530                 535                 540                 


Lys Ala Pro Ala Ala Lys Ala Gly Gly Pro Pro Lys Lys Gly Lys Pro 
545                 550                 555                 560 


Ala Ala Pro Gly Gly Ala Gly Asn Thr Gly Thr Lys Asn Lys Lys Gly 
                565                 570                 575     


Leu Glu Thr Lys Glu Ile Val Glu Pro Glu Leu Ser Ile Glu Val Cys 
            580                 585                 590         


Glu Glu Lys Ala Ser Ala Val Leu Pro Pro Thr Cys Ile Gln Leu Leu 
        595                 600                 605             


Asp Ser Ser Asn Trp Lys Glu Arg Leu Ala Cys Met Glu Glu Phe Gln 
    610                 615                 620                 


Lys Ala Val Glu Leu Met Asp Arg Thr Glu Met Pro Cys Gln Ala Leu 
625                 630                 635                 640 


Val Arg Met Leu Ala Lys Lys Pro Gly Trp Lys Glu Thr Asn Phe Gln 
                645                 650                 655     


Val Met Gln Met Lys Leu His Ile Val Ala Leu Ile Ala Gln Lys Gly 
            660                 665                 670         


Asn Phe Ser Lys Thr Ser Ala Gln Val Val Leu Asp Gly Leu Val Asp 
        675                 680                 685             


Lys Ile Gly Asp Val Lys Cys Gly Asn Asn Ala Lys Glu Ala Met Thr 
    690                 695                 700                 


Ala Ile Ala Glu Ala Cys Met Leu Pro Trp Thr Ala Glu Gln Val Val 
705                 710                 715                 720 


Ser Met Ala Phe Ser Gln Lys Asn Pro Lys Asn Gln Ser Glu Thr Leu 
                725                 730                 735     


Asn Trp Leu Ser Asn Ala Ile Lys Glu Phe Gly Phe Ser Gly Leu Asn 
            740                 745                 750         


Val Lys Ala Phe Ile Ser Asn Val Lys Thr Ala Leu Ala Ala Thr Asn 
        755                 760                 765             


Pro Ala Val Arg Thr Ala Ala Ile Thr Leu Leu Gly Val Met Tyr Leu 
    770                 775                 780                 


Tyr Val Gly Pro Ser Leu Arg Met Phe Phe Glu Asp Glu Lys Pro Ala 
785                 790                 795                 800 


Leu Leu Ser Gln Ile Asp Ala Glu Phe Glu Lys Met Gln Gly Gln Ser 
                805                 810                 815     


Pro Pro Ala Pro Thr Arg Gly Ile Ser Lys His Ser Thr Ser Gly Thr 
            820                 825                 830         


Asp Glu Gly Glu Asp Gly Asp Glu Pro Asp Asp Gly Ser Asn Asp Val 
        835                 840                 845             


Val Asp Leu Leu Pro Arg Thr Glu Ile Ser Asp Lys Ile Thr Ser Glu 
    850                 855                 860                 


Leu Val Ser Lys Ile Gly Asp Lys Asn Trp Lys Ile Arg Lys Glu Gly 
865                 870                 875                 880 


Leu Asp Glu Val Ala Gly Ile Ile Asn Asp Ala Lys Phe Ile Gln Pro 
                885                 890                 895     


Asn Ile Gly Glu Leu Pro Thr Ala Leu Lys Gly Arg Leu Asn Asp Ser 
            900                 905                 910         


Asn Lys Ile Leu Val Gln Gln Thr Leu Asn Ile Leu Gln Gln Leu Ala 
        915                 920                 925             


Val Ala Met Gly Pro Asn Ile Lys Gln His Val Lys Asn Leu Gly Ile 
    930                 935                 940                 


Pro Ile Ile Thr Val Leu Gly Asp Ser Lys Asn Asn Val Arg Ala Ala 
945                 950                 955                 960 


Ala Leu Ala Thr Val Asn Ala Trp Ala Glu Gln Thr Gly Met Lys Glu 
                965                 970                 975     


Trp Leu Glu Gly Glu Asp Leu Ser Glu Glu Leu Lys Lys Glu Asn Pro 
            980                 985                 990         


Phe Leu Arg Gln Glu Leu Leu Gly  Trp Leu Ala Glu Lys  Leu Pro Thr 
        995                 1000                 1005             


Leu Arg  Ser Thr Pro Thr Asp  Leu Ile Leu Cys Val  Pro His Leu 
    1010                 1015                 1020             


Tyr Ser  Cys Leu Glu Asp Arg  Asn Gly Asp Val Arg  Lys Lys Ala 
    1025                 1030                 1035             


Gln Asp  Ala Leu Pro Phe Phe  Met Met His Leu Gly  Tyr Glu Lys 
    1040                 1045                 1050             


Met Ala  Lys Ala Thr Gly Lys  Leu Lys Pro Thr Ser  Lys Asp Gln 
    1055                 1060                 1065             


Val Leu  Ala Met Leu Glu Lys  Ala Lys Val Asn Met  Pro Ala Lys 
    1070                 1075                 1080             


Pro Ala  Pro Pro Thr Lys Ala  Thr Ser Lys Pro Met  Gly Gly Ser 
    1085                 1090                 1095             


Ala Pro  Ala Lys Phe Gln Pro  Ala Ser Ala Pro Ala  Glu Asp Cys 
    1100                 1105                 1110             


Ile Ser  Ser Ser Thr Glu Pro  Lys Pro Asp Pro Lys  Lys Ala Lys 
    1115                 1120                 1125             


Ala Pro  Gly Leu Ser Ser Lys  Ala Lys Ser Ala Gln  Gly Lys Lys 
    1130                 1135                 1140             


Met Pro  Ser Lys Thr Ser Leu  Lys Glu Asp Glu Asp  Lys Ser Gly 
    1145                 1150                 1155             


Pro Ile  Phe Ile Val Val Pro  Asn Gly Lys Glu Gln  Arg Met Lys 
    1160                 1165                 1170             


Asp Glu  Lys Gly Leu Lys Val  Leu Lys Trp Asn Phe  Thr Thr Pro 
    1175                 1180                 1185             


Arg Asp  Glu Tyr Ile Glu Gln  Leu Lys Thr Gln Met  Ser Ser Cys 
    1190                 1195                 1200             


Val Ala  Lys Trp Leu Gln Asp  Glu Met Phe His Ser  Asp Phe Gln 
    1205                 1210                 1215             


His His  Asn Lys Ala Leu Ala  Val Met Val Asp His  Leu Glu Ser 
    1220                 1225                 1230             


Glu Lys  Glu Gly Val Ile Gly  Cys Leu Asp Leu Ile  Leu Lys Trp 
    1235                 1240                 1245             


Leu Thr  Leu Arg Phe Phe Asp  Thr Asn Thr Ser Val  Leu Met Lys 
    1250                 1255                 1260             


Ala Leu  Glu Tyr Leu Lys Leu  Leu Phe Thr Leu Leu  Ser Glu Glu 
    1265                 1270                 1275             


Glu Tyr  His Leu Thr Glu Asn  Glu Ala Ser Ser Phe  Ile Pro Tyr 
    1280                 1285                 1290             


Leu Val  Val Lys Val Gly Glu  Pro Lys Asp Val Ile  Arg Lys Asp 
    1295                 1300                 1305             


Val Arg  Ala Ile Leu Asn Arg  Met Cys Leu Val Tyr  Pro Ala Ser 
    1310                 1315                 1320             


Lys Met  Phe Pro Phe Ile Met  Glu Gly Thr Lys Ser  Lys Asn Ser 
    1325                 1330                 1335             


Lys Gln  Arg Ala Glu Cys Leu  Glu Glu Leu Gly Cys  Leu Val Glu 
    1340                 1345                 1350             


Ser Tyr  Gly Met Asn Val Cys  Gln Pro Thr Pro Gly  Lys Ala Leu 
    1355                 1360                 1365             


Lys Glu  Ile Ala Val His Ile  Gly Asp Arg Asp Asn  Ala Val Arg 
    1370                 1375                 1380             


Asn Ala  Ala Leu Asn Thr Ile  Val Thr Val Tyr Asn  Val His Gly 
    1385                 1390                 1395             


Asp Gln  Val Phe Lys Leu Ile  Gly Asn Leu Ser Glu  Lys Asp Met 
    1400                 1405                 1410             


Ser Met  Leu Glu Glu Arg Ile  Lys Arg Ser Ala Lys  Arg Pro Ser 
    1415                 1420                 1425             


Ala Ala  Pro Ile Lys Gln Val  Glu Glu Lys Pro Gln  Arg Ala Gln 
    1430                 1435                 1440             


Asn Ile  Ser Ser Asn Ala Asn  Met Leu Arg Lys Gly  Pro Ala Glu 
    1445                 1450                 1455             


Asp Met  Ser Ser Lys Leu Asn  Gln Ala Arg Ser Met  Ser Gly His 
    1460                 1465                 1470             


Pro Glu  Ala Ala Gln Met Val  Arg Arg Glu Phe Gln  Leu Asp Leu 
    1475                 1480                 1485             


Asp Glu  Ile Glu Asn Asp Asn  Gly Thr Val Arg Cys  Glu Met Pro 
    1490                 1495                 1500             


Glu Leu  Val Gln His Lys Leu  Asp Asp Ile Phe Glu  Pro Val Leu 
    1505                 1510                 1515             


Ile Pro  Glu Pro Lys Ile Arg  Ala Val Ser Pro His  Phe Asp Asp 
    1520                 1525                 1530             


Met His  Ser Asn Thr Ala Ser  Thr Ile Asn Phe Ile  Ile Ser Gln 
    1535                 1540                 1545             


Val Ala  Ser Gly Asp Ile Asn  Thr Ser Ile Gln Ala  Leu Thr Gln 
    1550                 1555                 1560             


Ile Asp  Glu Val Leu Arg Gln  Glu Asp Lys Ala Glu  Ala Met Ser 
    1565                 1570                 1575             


Gly His  Ile Asp Gln Phe Leu  Ile Ala Thr Phe Met  Gln Leu Arg 
    1580                 1585                 1590             


Leu Ile  Tyr Asn Thr His Met  Ala Asp Glu Lys Leu  Glu Lys Asp 
    1595                 1600                 1605             


Glu Ile  Ile Lys Leu Tyr Ser  Cys Ile Ile Gly Asn  Met Ile Ser 
    1610                 1615                 1620             


Leu Phe  Gln Ile Glu Ser Leu  Ala Arg Glu Ala Ser  Thr Gly Val 
    1625                 1630                 1635             


Leu Lys  Asp Leu Met His Gly  Leu Ile Thr Leu Met  Leu Asp Ser 
    1640                 1645                 1650             


Arg Ile  Glu Asp Leu Glu Glu  Gly Gln Gln Val Ile  Arg Ser Val 
    1655                 1660                 1665             


Asn Leu  Leu Val Val Lys Val  Leu Glu Lys Ser Asp  Gln Thr Asn 
    1670                 1675                 1680             


Ile Leu  Ser Ala Leu Leu Val  Leu Leu Gln Asp Ser  Leu Leu Ala 
    1685                 1690                 1695             


Thr Ala  Ser Ser Pro Lys Phe  Ser Glu Leu Val Met  Lys Cys Leu 
    1700                 1705                 1710             


Trp Arg  Met Val Arg Leu Leu  Pro Asp Thr Ile Asn  Ser Ile Asn 
    1715                 1720                 1725             


Leu Asp  Arg Ile Leu Leu Asp  Ile His Ile Phe Met  Lys Val Phe 
    1730                 1735                 1740             


Pro Lys  Glu Lys Leu Lys Gln  Cys Lys Ser Glu Phe  Pro Ile Arg 
    1745                 1750                 1755             


Thr Leu  Lys Thr Leu Leu His  Thr Leu Cys Lys Leu  Lys Gly Pro 
    1760                 1765                 1770             


Lys Ile  Leu Asp His Leu Thr  Met Ile Asp Asn Lys  Asn Glu Ser 
    1775                 1780                 1785             


Glu Leu  Glu Ala His Leu Cys  Arg Met Met Lys His  Ser Met Asp 
    1790                 1795                 1800             


Gln Thr  Gly Ser Lys Ser Asp  Lys Glu Thr Glu Lys  Gly Ala Ser 
    1805                 1810                 1815             


Arg Ile  Asp Glu Lys Ser Ser  Lys Ala Lys Val Asn  Asp Phe Leu 
    1820                 1825                 1830             


Ala Glu  Ile Phe Lys Lys Ile  Gly Ser Lys Glu Asn  Thr Lys Glu 
    1835                 1840                 1845             


Gly Leu  Ala Glu Leu Tyr Glu  Tyr Lys Lys Lys Tyr  Ser Asp Ala 
    1850                 1855                 1860             


Asp Ile  Glu Pro Phe Leu Lys  Asn Ser Ser Gln Phe  Phe Gln Ser 
    1865                 1870                 1875             


Tyr Val  Glu Arg Gly Leu Arg  Val Ile Glu Met Glu  Arg Glu Gly 
    1880                 1885                 1890             


Lys Gly  Arg Ile Ser Thr Ser  Thr Gly Ile Ser Pro  Gln Met Glu 
    1895                 1900                 1905             


Val Thr  Cys Val Pro Thr Pro  Thr Ser Thr Val Ser  Ser Ile Gly 
    1910                 1915                 1920             


Asn Thr  Asn Gly Glu Glu Val  Gly Pro Ser Val Tyr  Leu Glu Arg 
    1925                 1930                 1935             


Leu Lys  Ile Leu Arg Gln Arg  Cys Gly Leu Asp Asn  Thr Lys Gln 
    1940                 1945                 1950             


Asp Asp  Arg Pro Pro Leu Thr  Ser Leu Leu Ser Lys  Pro Ala Val 
    1955                 1960                 1965             


Pro Thr  Val Ala Ser Ser Thr  Asp Met Leu His Ser  Lys Leu Ser 
    1970                 1975                 1980             


Gln Leu  Arg Glu Ser Arg Glu  Gln His Gln His Ser  Asp Leu Asp 
    1985                 1990                 1995             


Ser Asn  Gln Thr His Ser Ser  Gly Thr Val Thr Ser  Ser Ser Ser 
    2000                 2005                 2010             


Thr Ala  Asn Ile Asp Asp Leu  Lys Lys Arg Leu Glu  Arg Ile Lys 
    2015                 2020                 2025             


Ser Ser  Arg Lys 
    2030         


<210>  3232
<211>  1314
<212>  PRT
<213>  homo sapiens

<400>  3232

Met Leu Asp Pro Ser Ser Ser Glu Glu Glu Ser Asp Glu Ile Val Glu 
1               5                   10                  15      


Glu Glu Ser Gly Lys Glu Val Leu Gly Ser Ala Pro Ser Gly Ala Arg 
            20                  25                  30          


Leu Ser Pro Ser Arg Thr Ser Glu Gly Ser Ala Gly Ser Ala Gly Leu 
        35                  40                  45              


Gly Gly Gly Gly Ala Gly Ala Gly Ala Gly Val Gly Ala Gly Gly Gly 
    50                  55                  60                  


Gly Gly Ser Gly Ala Ser Ser Gly Gly Gly Ala Gly Gly Leu Gln Pro 
65                  70                  75                  80  


Ser Ser Arg Ala Gly Gly Gly Arg Pro Ser Ser Pro Ser Pro Ser Val 
                85                  90                  95      


Val Ser Glu Lys Glu Lys Glu Glu Leu Glu Arg Leu Gln Lys Glu Glu 
            100                 105                 110         


Glu Glu Arg Lys Lys Arg Leu Gln Leu Tyr Val Phe Val Met Arg Cys 
        115                 120                 125             


Ile Ala Tyr Pro Phe Asn Ala Lys Gln Pro Thr Asp Met Ala Arg Arg 
    130                 135                 140                 


Gln Gln Lys Ile Ser Lys Gln Gln Leu Gln Thr Val Lys Asp Arg Phe 
145                 150                 155                 160 


Gln Ala Phe Leu Asn Gly Glu Thr Gln Ile Met Ala Asp Glu Ala Phe 
                165                 170                 175     


Met Asn Ala Val Gln Ser Tyr Tyr Glu Val Phe Leu Lys Ser Asp Arg 
            180                 185                 190         


Val Ala Arg Met Val Gln Ser Gly Gly Cys Ser Ala Asn Asp Ser Arg 
        195                 200                 205             


Glu Val Phe Lys Lys His Ile Glu Lys Arg Val Arg Ser Leu Pro Glu 
    210                 215                 220                 


Ile Asp Gly Leu Ser Lys Glu Thr Val Leu Ser Ser Trp Met Ala Lys 
225                 230                 235                 240 


Phe Asp Ala Ile Tyr Arg Gly Glu Glu Asp Pro Arg Lys Gln Gln Ala 
                245                 250                 255     


Arg Met Thr Ala Ser Ala Ala Ser Glu Leu Ile Leu Ser Lys Glu Gln 
            260                 265                 270         


Leu Tyr Glu Met Phe Gln Asn Ile Leu Gly Ile Lys Lys Phe Glu His 
        275                 280                 285             


Gln Leu Leu Tyr Asn Ala Cys Gln Leu Asp Asn Pro Asp Glu Gln Ala 
    290                 295                 300                 


Ala Gln Ile Arg Arg Glu Leu Asp Gly Arg Leu Gln Met Ala Asp Gln 
305                 310                 315                 320 


Ile Ala Arg Glu Arg Lys Phe Pro Lys Phe Val Ser Lys Glu Met Glu 
                325                 330                 335     


Asn Met Tyr Ile Glu Glu Leu Lys Ser Ser Val Asn Leu Leu Met Ala 
            340                 345                 350         


Asn Leu Glu Ser Met Pro Val Ser Lys Gly Gly Glu Phe Lys Leu Gln 
        355                 360                 365             


Lys Leu Lys Arg Ser His Asn Ala Ser Ile Ile Asp Met Gly Glu Glu 
    370                 375                 380                 


Ser Glu Asn Gln Leu Ser Lys Ser Asp Val Val Leu Ser Phe Ser Leu 
385                 390                 395                 400 


Glu Val Val Ile Met Glu Val Gln Gly Leu Lys Ser Leu Ala Pro Asn 
                405                 410                 415     


Arg Ile Val Tyr Cys Thr Met Glu Val Glu Gly Gly Glu Lys Leu Gln 
            420                 425                 430         


Thr Asp Gln Ala Glu Ala Ser Lys Pro Thr Trp Gly Thr Gln Gly Asp 
        435                 440                 445             


Phe Ser Thr Thr His Ala Leu Pro Ala Val Lys Val Lys Leu Phe Thr 
    450                 455                 460                 


Glu Ser Thr Gly Val Leu Ala Leu Glu Asp Lys Glu Leu Gly Arg Val 
465                 470                 475                 480 


Ile Leu His Pro Thr Pro Asn Ser Pro Lys Gln Ser Glu Trp His Lys 
                485                 490                 495     


Met Thr Val Ser Lys Asn Cys Pro Asp Gln Asp Leu Lys Ile Lys Leu 
            500                 505                 510         


Ala Val Arg Met Asp Lys Pro Gln Asn Met Lys His Ser Gly Tyr Leu 
        515                 520                 525             


Trp Ala Ile Gly Lys Asn Val Trp Lys Arg Trp Lys Lys Arg Phe Phe 
    530                 535                 540                 


Val Leu Val Gln Val Ser Gln Tyr Thr Phe Ala Met Cys Ser Tyr Arg 
545                 550                 555                 560 


Glu Lys Lys Ala Glu Pro Gln Glu Leu Leu Gln Leu Asp Gly Tyr Thr 
                565                 570                 575     


Val Asp Tyr Thr Asp Pro Gln Pro Gly Leu Glu Gly Gly Arg Ala Phe 
            580                 585                 590         


Phe Asn Ala Val Lys Glu Gly Asp Thr Val Ile Phe Ala Ser Asp Asp 
        595                 600                 605             


Glu Gln Asp Arg Ile Leu Trp Val Gln Ala Met Tyr Arg Ala Thr Gly 
    610                 615                 620                 


Gln Ser His Lys Pro Val Pro Pro Thr Gln Val Gln Lys Leu Asn Ala 
625                 630                 635                 640 


Lys Gly Gly Asn Val Pro Gln Leu Asp Ala Pro Ile Ser Gln Phe Tyr 
                645                 650                 655     


Ala Asp Arg Ala Gln Lys His Gly Met Asp Glu Phe Ile Ser Ser Asn 
            660                 665                 670         


Pro Cys Asn Phe Asp His Ala Ser Leu Phe Glu Met Val Gln Arg Leu 
        675                 680                 685             


Thr Leu Asp His Arg Leu Asn Asp Ser Tyr Ser Cys Leu Gly Trp Phe 
    690                 695                 700                 


Ser Pro Gly Gln Val Phe Val Leu Asp Glu Tyr Cys Ala Arg Asn Gly 
705                 710                 715                 720 


Val Arg Gly Cys His Arg His Leu Cys Tyr Leu Arg Asp Leu Leu Glu 
                725                 730                 735     


Arg Ala Glu Asn Gly Ala Met Ile Asp Pro Thr Leu Leu His Tyr Ser 
            740                 745                 750         


Phe Ala Phe Cys Ala Ser His Val His Gly Asn Arg Pro Asp Gly Ile 
        755                 760                 765             


Gly Thr Val Thr Val Glu Glu Lys Glu Arg Phe Glu Glu Ile Lys Glu 
    770                 775                 780                 


Arg Leu Arg Val Leu Leu Glu Asn Gln Ile Thr His Phe Arg Tyr Cys 
785                 790                 795                 800 


Phe Pro Phe Gly Arg Pro Glu Gly Ala Leu Lys Ala Thr Leu Ser Leu 
                805                 810                 815     


Leu Glu Arg Val Leu Met Lys Asp Ile Val Thr Pro Val Pro Gln Glu 
            820                 825                 830         


Glu Val Lys Thr Val Ile Arg Lys Cys Leu Glu Gln Ala Ala Leu Val 
        835                 840                 845             


Asn Tyr Ser Arg Leu Ser Glu Tyr Ala Lys Ile Glu Gly Lys Lys Arg 
    850                 855                 860                 


Glu Met Tyr Glu His Pro Val Phe Cys Leu Ala Ser Gln Val Met Asp 
865                 870                 875                 880 


Leu Thr Ile Gln Asn Val Gly Arg Leu Ile Thr Pro Ala Lys Lys Leu 
                885                 890                 895     


Glu Asp Thr Ile Arg Leu Ala Glu Leu Val Ile Glu Val Leu Gln Gln 
            900                 905                 910         


Asn Glu Glu His His Ala Glu Ala Phe Ala Trp Trp Ser Asp Leu Met 
        915                 920                 925             


Val Glu His Ala Glu Thr Phe Leu Ser Leu Phe Ala Val Asp Met Asp 
    930                 935                 940                 


Ala Ala Leu Glu Val Gln Pro Pro Asp Thr Trp Asp Ser Phe Pro Leu 
945                 950                 955                 960 


Phe Gln Leu Leu Asn Asp Phe Leu Arg Thr Asp Tyr Asn Leu Cys Asn 
                965                 970                 975     


Gly Lys Phe His Lys His Leu Gln Asp Leu Phe Ala Pro Leu Val Val 
            980                 985                 990         


Arg Tyr Val Asp Leu Met Glu Ser  Ser Ile Ala Gln Ser  Ile His Arg 
        995                 1000                 1005             


Gly Phe  Glu Arg Glu Ser Trp  Glu Pro Val Asn Asn  Gly Ser Gly 
    1010                 1015                 1020             


Thr Ser  Glu Asp Leu Phe Trp  Lys Leu Asp Ala Leu  Gln Thr Phe 
    1025                 1030                 1035             


Ile Arg  Asp Leu His Trp Pro  Glu Glu Glu Phe Gly  Lys His Leu 
    1040                 1045                 1050             


Glu Gln  Arg Leu Lys Leu Met  Ala Ser Asp Met Ile  Glu Ser Cys 
    1055                 1060                 1065             


Val Lys  Arg Thr Arg Ile Ala  Phe Glu Val Lys Leu  Gln Lys Thr 
    1070                 1075                 1080             


Ser Arg  Ser Thr Asp Phe Arg  Val Pro Gln Ser Ile  Cys Thr Met 
    1085                 1090                 1095             


Phe Asn  Val Met Val Asp Ala  Lys Ala Gln Ser Thr  Lys Leu Cys 
    1100                 1105                 1110             


Ser Met  Glu Met Gly Gln Glu  His Gln Tyr His Ser  Lys Ile Asp 
    1115                 1120                 1125             


Glu Leu  Ile Glu Glu Thr Val  Lys Glu Met Ile Thr  Leu Leu Val 
    1130                 1135                 1140             


Ala Lys  Phe Val Thr Ile Leu  Glu Gly Val Leu Ala  Lys Leu Ser 
    1145                 1150                 1155             


Arg Tyr  Asp Glu Gly Thr Leu  Phe Ser Ser Phe Leu  Ser Phe Thr 
    1160                 1165                 1170             


Val Lys  Ala Ala Ser Lys Tyr  Val Asp Val Pro Lys  Pro Gly Met 
    1175                 1180                 1185             


Asp Val  Ala Asp Ala Tyr Val  Thr Phe Val Arg His  Ser Gln Asp 
    1190                 1195                 1200             


Val Leu  Arg Asp Lys Val Asn  Glu Glu Met Tyr Ile  Glu Arg Leu 
    1205                 1210                 1215             


Phe Asp  Gln Trp Tyr Asn Ser  Ser Met Asn Val Ile  Cys Thr Trp 
    1220                 1225                 1230             


Leu Thr  Asp Arg Met Asp Leu  Gln Leu His Ile Tyr  Gln Leu Lys 
    1235                 1240                 1245             


Thr Leu  Ile Arg Met Val Lys  Lys Thr Tyr Arg Asp  Phe Arg Leu 
    1250                 1255                 1260             


Gln Gly  Val Leu Asp Ser Thr  Leu Asn Ser Lys Thr  Tyr Glu Thr 
    1265                 1270                 1275             


Ile Arg  Asn Arg Leu Thr Val  Glu Glu Ala Thr Ala  Ser Val Ser 
    1280                 1285                 1290             


Glu Gly  Gly Gly Leu Gln Gly  Ile Ser Met Lys Asp  Ser Asp Glu 
    1295                 1300                 1305             


Glu Asp  Glu Glu Asp Asp 
    1310                 


<210>  3233
<211>  723
<212>  PRT
<213>  homo sapiens

<400>  3233

Met Gly Ser Arg Cys Ala Leu Ala Leu Ala Val Leu Ser Ala Leu Leu 
1               5                   10                  15      


Cys Gln Val Trp Ser Ser Gly Val Phe Glu Leu Lys Leu Gln Glu Phe 
            20                  25                  30          


Val Asn Lys Lys Gly Leu Leu Gly Asn Arg Asn Cys Cys Arg Gly Gly 
        35                  40                  45              


Ala Gly Pro Pro Pro Cys Ala Cys Arg Thr Phe Phe Arg Val Cys Leu 
    50                  55                  60                  


Lys His Tyr Gln Ala Ser Val Ser Pro Glu Pro Pro Cys Thr Tyr Gly 
65                  70                  75                  80  


Ser Ala Val Thr Pro Val Leu Gly Val Asp Ser Phe Ser Leu Pro Asp 
                85                  90                  95      


Gly Gly Gly Ala Asp Ser Ala Phe Ser Asn Pro Ile Arg Phe Pro Phe 
            100                 105                 110         


Gly Phe Thr Trp Pro Gly Thr Phe Ser Leu Ile Ile Glu Ala Leu His 
        115                 120                 125             


Thr Asp Ser Pro Asp Asp Leu Ala Thr Glu Asn Pro Glu Arg Leu Ile 
    130                 135                 140                 


Ser Arg Leu Ala Thr Gln Arg His Leu Thr Val Gly Glu Glu Trp Ser 
145                 150                 155                 160 


Gln Asp Leu His Ser Ser Gly Arg Thr Asp Leu Lys Tyr Ser Tyr Arg 
                165                 170                 175     


Phe Val Cys Asp Glu His Tyr Tyr Gly Glu Gly Cys Ser Val Phe Cys 
            180                 185                 190         


Arg Pro Arg Asp Asp Ala Phe Gly His Phe Thr Cys Gly Glu Arg Gly 
        195                 200                 205             


Glu Lys Val Cys Asn Pro Gly Trp Lys Gly Pro Tyr Cys Thr Glu Pro 
    210                 215                 220                 


Ile Cys Leu Pro Gly Cys Asp Glu Gln His Gly Phe Cys Asp Lys Pro 
225                 230                 235                 240 


Gly Glu Cys Lys Cys Arg Val Gly Trp Gln Gly Arg Tyr Cys Asp Glu 
                245                 250                 255     


Cys Ile Arg Tyr Pro Gly Cys Leu His Gly Thr Cys Gln Gln Pro Trp 
            260                 265                 270         


Gln Cys Asn Cys Gln Glu Gly Trp Gly Gly Leu Phe Cys Asn Gln Asp 
        275                 280                 285             


Leu Asn Tyr Cys Thr His His Lys Pro Cys Lys Asn Gly Ala Thr Cys 
    290                 295                 300                 


Thr Asn Thr Gly Gln Gly Ser Tyr Thr Cys Ser Cys Arg Pro Gly Tyr 
305                 310                 315                 320 


Thr Gly Ala Thr Cys Glu Leu Gly Ile Asp Glu Cys Asp Pro Ser Pro 
                325                 330                 335     


Cys Lys Asn Gly Gly Ser Cys Thr Asp Leu Glu Asn Ser Tyr Ser Cys 
            340                 345                 350         


Thr Cys Pro Pro Gly Phe Tyr Gly Lys Ile Cys Glu Leu Ser Ala Met 
        355                 360                 365             


Thr Cys Ala Asp Gly Pro Cys Phe Asn Gly Gly Arg Cys Ser Asp Ser 
    370                 375                 380                 


Pro Asp Gly Gly Tyr Ser Cys Arg Cys Pro Val Gly Tyr Ser Gly Phe 
385                 390                 395                 400 


Asn Cys Glu Lys Lys Ile Asp Tyr Cys Ser Ser Ser Pro Cys Ser Asn 
                405                 410                 415     


Gly Ala Lys Cys Val Asp Leu Gly Asp Ala Tyr Leu Cys Arg Cys Gln 
            420                 425                 430         


Ala Gly Phe Ser Gly Arg His Cys Asp Asp Asn Val Asp Asp Cys Ala 
        435                 440                 445             


Ser Ser Pro Cys Ala Asn Gly Gly Thr Cys Arg Asp Gly Val Asn Asp 
    450                 455                 460                 


Phe Ser Cys Thr Cys Pro Pro Gly Tyr Thr Gly Arg Asn Cys Ser Ala 
465                 470                 475                 480 


Pro Val Ser Arg Cys Glu His Ala Pro Cys His Asn Gly Ala Thr Cys 
                485                 490                 495     


His Glu Arg Gly His Arg Tyr Val Cys Glu Cys Ala Arg Gly Tyr Gly 
            500                 505                 510         


Gly Pro Asn Cys Gln Phe Leu Leu Pro Glu Leu Pro Pro Gly Pro Ala 
        515                 520                 525             


Val Val Asp Leu Thr Glu Lys Leu Glu Gly Gln Gly Gly Pro Phe Pro 
    530                 535                 540                 


Trp Val Ala Val Cys Ala Gly Val Ile Leu Val Leu Met Leu Leu Leu 
545                 550                 555                 560 


Gly Cys Ala Ala Val Val Val Cys Val Arg Leu Arg Leu Gln Lys His 
                565                 570                 575     


Arg Pro Pro Ala Asp Pro Cys Arg Gly Glu Thr Glu Thr Met Asn Asn 
            580                 585                 590         


Leu Ala Asn Cys Gln Arg Glu Lys Asp Ile Ser Val Ser Ile Ile Gly 
        595                 600                 605             


Ala Thr Gln Ile Lys Asn Thr Asn Lys Lys Ala Asp Phe His Gly Asp 
    610                 615                 620                 


His Ser Ala Asp Lys Asn Gly Phe Lys Ala Arg Tyr Pro Ala Val Asp 
625                 630                 635                 640 


Tyr Asn Leu Val Gln Asp Leu Lys Gly Asp Asp Thr Ala Val Arg Asp 
                645                 650                 655     


Ala His Ser Lys Arg Asp Thr Lys Cys Gln Pro Gln Gly Ser Ser Gly 
            660                 665                 670         


Glu Glu Lys Gly Thr Pro Thr Thr Leu Arg Gly Gly Glu Ala Ser Glu 
        675                 680                 685             


Arg Lys Arg Pro Asp Ser Gly Cys Ser Thr Ser Lys Asp Thr Lys Tyr 
    690                 695                 700                 


Gln Ser Val Tyr Val Ile Ser Glu Glu Lys Asp Glu Cys Val Ile Ala 
705                 710                 715                 720 


Thr Glu Val 
            


<210>  3234
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  3234

Met Glu Gln His Phe Leu Gly Cys Val Lys Arg Ala Trp Asp Ser Ala 
1               5                   10                  15      


Glu Val Ala Pro Glu Pro Gln Pro Pro Pro Ile Val Ser Ser Glu Asp 
            20                  25                  30          


Arg Gly Pro Trp Pro Leu Pro Leu Tyr Pro Val Leu Gly Glu Tyr Ser 
        35                  40                  45              


Leu Asp Ser Cys Asp Leu Gly Leu Leu Ser Ser Pro Cys Trp Arg Leu 
    50                  55                  60                  


Pro Gly Val Tyr Trp Gln Asn Gly Leu Ser Pro Gly Val Gln Ser Thr 
65                  70                  75                  80  


Leu Glu Pro Ser Thr Ala Lys Pro Thr Glu Phe Ser Trp Pro Gly Thr 
                85                  90                  95      


Gln Lys Gln Gln Glu Ala Pro Val Glu Glu Val Gly Gln Ala Glu Glu 
            100                 105                 110         


Pro Asp Arg Leu Arg Leu Gln Gln Leu Pro Trp Ser Ser Pro Leu His 
        115                 120                 125             


Pro Trp Asp Arg Gln Gln Asp Thr Glu Val Cys Asp Ser Gly Cys Leu 
    130                 135                 140                 


Leu Glu Arg Arg His Pro Pro Ala Leu Gln Pro Trp Arg His Leu Pro 
145                 150                 155                 160 


Gly Phe Ser Asp Cys Leu Glu Trp Ile Leu Arg Val Gly Phe Ala Ala 
                165                 170                 175     


Phe Ser Val Leu Trp Ala Cys Cys Ser Arg Ile Cys Gly Ala Lys Gln 
            180                 185                 190         


Pro 
    


<210>  3235
<211>  471
<212>  PRT
<213>  homo sapiens

<400>  3235

Met Ser Asp Phe Asp Glu Phe Glu Arg Gln Leu Asn Glu Asn Lys Gln 
1               5                   10                  15      


Glu Arg Asp Lys Glu Asn Arg His Arg Lys Arg Ser His Ser Arg Ser 
            20                  25                  30          


Arg Ser Arg Asp Arg Lys Arg Arg Ser Arg Ser Arg Asp Arg Arg Asn 
        35                  40                  45              


Arg Asp Gln Arg Ser Ala Ser Arg Asp Arg Arg Arg Arg Ser Lys Pro 
    50                  55                  60                  


Leu Thr Arg Gly Ala Lys Glu Glu His Gly Gly Leu Ile Arg Ser Pro 
65                  70                  75                  80  


Arg His Glu Lys Lys Lys Lys Val Arg Lys Tyr Trp Asp Val Pro Pro 
                85                  90                  95      


Pro Gly Phe Glu His Ile Thr Pro Met Gln Tyr Lys Ala Met Gln Ala 
            100                 105                 110         


Ala Gly Gln Ile Pro Ala Thr Ala Leu Leu Pro Thr Met Thr Pro Asp 
        115                 120                 125             


Gly Leu Ala Val Thr Pro Thr Pro Val Pro Val Val Gly Ser Gln Met 
    130                 135                 140                 


Thr Arg Gln Ala Arg Arg Leu Tyr Val Gly Asn Ile Pro Phe Gly Ile 
145                 150                 155                 160 


Thr Glu Glu Ala Met Met Asp Phe Phe Asn Ala Gln Met Arg Leu Gly 
                165                 170                 175     


Gly Leu Thr Gln Ala Pro Gly Asn Pro Val Leu Ala Val Gln Ile Asn 
            180                 185                 190         


Gln Asp Lys Asn Phe Ala Phe Leu Glu Phe Arg Ser Val Asp Glu Thr 
        195                 200                 205             


Thr Gln Ala Met Ala Phe Asp Gly Ile Ile Phe Gln Gly Gln Ser Leu 
    210                 215                 220                 


Lys Ile Arg Arg Pro His Asp Tyr Gln Pro Leu Pro Gly Met Ser Glu 
225                 230                 235                 240 


Asn Pro Ser Val Tyr Val Pro Gly Val Val Ser Thr Val Val Pro Asp 
                245                 250                 255     


Ser Ala His Lys Leu Phe Ile Gly Gly Leu Pro Asn Tyr Leu Asn Asp 
            260                 265                 270         


Asp Gln Val Lys Glu Leu Leu Thr Ser Phe Gly Pro Leu Lys Ala Phe 
        275                 280                 285             


Asn Leu Val Lys Asp Ser Ala Thr Gly Leu Ser Lys Gly Tyr Ala Phe 
    290                 295                 300                 


Cys Glu Tyr Val Asp Ile Asn Val Thr Asp Gln Ala Ile Ala Gly Leu 
305                 310                 315                 320 


Asn Gly Met Gln Leu Gly Asp Lys Lys Leu Leu Val Gln Arg Ala Ser 
                325                 330                 335     


Val Gly Ala Lys Asn Ala Thr Leu Ser Thr Ile Asn Gln Thr Pro Val 
            340                 345                 350         


Thr Leu Gln Val Pro Gly Leu Met Ser Ser Gln Val Gln Met Gly Gly 
        355                 360                 365             


His Pro Thr Glu Val Leu Cys Leu Met Asn Met Val Leu Pro Glu Glu 
    370                 375                 380                 


Leu Leu Asp Asp Glu Glu Tyr Glu Glu Ile Val Glu Asp Val Arg Asp 
385                 390                 395                 400 


Glu Cys Ser Lys Tyr Gly Leu Val Lys Ser Ile Glu Ile Pro Arg Pro 
                405                 410                 415     


Val Asp Gly Val Glu Val Pro Gly Cys Gly Lys Ile Phe Val Glu Phe 
            420                 425                 430         


Thr Ser Val Phe Asp Cys Gln Lys Ala Met Gln Gly Leu Thr Gly Arg 
        435                 440                 445             


Lys Phe Ala Asn Arg Val Val Val Thr Lys Tyr Cys Asp Pro Asp Ser 
    450                 455                 460                 


Tyr His Arg Arg Asp Phe Trp 
465                 470     


<210>  3236
<211>  1058
<212>  PRT
<213>  homo sapiens

<400>  3236

Met Ser Ser Ser Pro Leu Ser Lys Lys Arg Arg Val Ser Gly Pro Asp 
1               5                   10                  15      


Pro Lys Pro Gly Ser Asn Cys Ser Pro Ala Gln Ser Val Leu Ser Glu 
            20                  25                  30          


Val Pro Ser Val Pro Thr Asn Gly Met Ala Lys Asn Gly Ser Glu Ala 
        35                  40                  45              


Asp Ile Asp Glu Gly Leu Tyr Ser Arg Gln Leu Tyr Val Leu Gly His 
    50                  55                  60                  


Glu Ala Met Lys Arg Leu Gln Thr Ser Ser Val Leu Val Ser Gly Leu 
65                  70                  75                  80  


Arg Gly Leu Gly Val Glu Ile Ala Lys Asn Ile Ile Leu Gly Gly Val 
                85                  90                  95      


Lys Ala Val Thr Leu His Asp Gln Gly Thr Ala Gln Trp Ala Asp Leu 
            100                 105                 110         


Ser Ser Gln Phe Tyr Leu Arg Glu Glu Asp Ile Gly Lys Asn Arg Ala 
        115                 120                 125             


Glu Val Ser Gln Pro Arg Leu Ala Glu Leu Asn Ser Tyr Val Pro Val 
    130                 135                 140                 


Thr Ala Tyr Thr Gly Pro Leu Val Glu Asp Phe Leu Ser Gly Phe Gln 
145                 150                 155                 160 


Val Val Val Leu Thr Asn Thr Pro Leu Glu Asp Gln Leu Arg Val Gly 
                165                 170                 175     


Glu Phe Cys His Asn Arg Gly Ile Lys Leu Val Val Ala Asp Thr Arg 
            180                 185                 190         


Gly Leu Phe Gly Gln Leu Phe Cys Asp Phe Gly Glu Glu Met Ile Leu 
        195                 200                 205             


Thr Asp Ser Asn Gly Glu Gln Pro Leu Ser Ala Met Val Ser Met Val 
    210                 215                 220                 


Thr Lys Asp Asn Pro Gly Val Val Thr Cys Leu Asp Glu Ala Arg His 
225                 230                 235                 240 


Gly Phe Glu Ser Gly Asp Phe Val Ser Phe Ser Glu Val Gln Gly Met 
                245                 250                 255     


Val Glu Leu Asn Gly Asn Gln Pro Met Glu Ile Lys Val Leu Gly Pro 
            260                 265                 270         


Tyr Thr Phe Ser Ile Cys Asp Thr Ser Asn Phe Ser Asp Tyr Ile Arg 
        275                 280                 285             


Gly Gly Ile Val Ser Gln Val Lys Val Pro Lys Lys Ile Ser Phe Lys 
    290                 295                 300                 


Ser Leu Val Ala Ser Leu Ala Glu Pro Asp Phe Val Val Thr Asp Phe 
305                 310                 315                 320 


Ala Lys Phe Ser Arg Pro Ala Gln Leu His Ile Gly Phe Gln Ala Leu 
                325                 330                 335     


His Gln Phe Cys Ala Gln His Gly Arg Pro Pro Arg Pro Arg Asn Glu 
            340                 345                 350         


Glu Asp Ala Ala Glu Leu Val Ala Leu Ala Gln Ala Val Asn Ala Arg 
        355                 360                 365             


Ala Leu Pro Ala Val Gln Gln Asn Asn Leu Asp Glu Asp Leu Ile Arg 
    370                 375                 380                 


Lys Leu Ala Tyr Val Ala Ala Gly Asp Leu Ala Pro Ile Asn Ala Phe 
385                 390                 395                 400 


Ile Gly Gly Leu Ala Ala Gln Glu Val Met Lys Ala Cys Ser Gly Lys 
                405                 410                 415     


Phe Met Pro Ile Met Gln Trp Leu Tyr Phe Asp Ala Leu Glu Cys Leu 
            420                 425                 430         


Pro Glu Asp Lys Glu Val Leu Thr Glu Asp Lys Cys Leu Gln Arg Gln 
        435                 440                 445             


Asn Arg Tyr Asp Gly Gln Val Ala Val Phe Gly Ser Asp Leu Gln Glu 
    450                 455                 460                 


Lys Leu Gly Lys Gln Lys Tyr Phe Leu Val Gly Ala Gly Ala Ile Gly 
465                 470                 475                 480 


Cys Glu Leu Leu Lys Asn Phe Ala Met Ile Gly Leu Gly Cys Gly Glu 
                485                 490                 495     


Gly Gly Glu Ile Ile Val Thr Asp Met Asp Thr Ile Glu Lys Ser Asn 
            500                 505                 510         


Leu Asn Arg Gln Phe Leu Phe Arg Pro Trp Asp Val Thr Lys Leu Lys 
        515                 520                 525             


Ser Asp Thr Ala Ala Ala Ala Val Arg Gln Met Asn Pro His Ile Arg 
    530                 535                 540                 


Val Thr Ser His Gln Asn Arg Val Gly Pro Asp Thr Glu Arg Ile Tyr 
545                 550                 555                 560 


Asp Asp Asp Phe Phe Gln Asn Leu Asp Gly Val Ala Asn Ala Leu Asp 
                565                 570                 575     


Asn Val Asp Ala Arg Met Tyr Met Asp Arg Arg Cys Val Tyr Tyr Arg 
            580                 585                 590         


Lys Pro Leu Leu Glu Ser Gly Thr Leu Gly Thr Lys Gly Asn Val Gln 
        595                 600                 605             


Val Val Ile Pro Phe Leu Thr Glu Ser Tyr Ser Ser Ser Gln Asp Pro 
    610                 615                 620                 


Pro Glu Lys Ser Ile Pro Ile Cys Thr Leu Lys Asn Phe Pro Asn Ala 
625                 630                 635                 640 


Ile Glu His Thr Leu Gln Trp Ala Arg Asp Glu Phe Glu Gly Leu Phe 
                645                 650                 655     


Lys Gln Pro Ala Glu Asn Val Asn Gln Tyr Leu Thr Asp Pro Lys Phe 
            660                 665                 670         


Val Glu Arg Thr Leu Arg Leu Ala Gly Thr Gln Pro Leu Glu Val Leu 
        675                 680                 685             


Glu Ala Val Gln Arg Ser Leu Val Leu Gln Arg Pro Gln Thr Trp Ala 
    690                 695                 700                 


Asp Cys Val Thr Trp Ala Cys His His Trp His Thr Gln Tyr Ser Asn 
705                 710                 715                 720 


Asn Ile Arg Gln Leu Leu His Asn Phe Pro Pro Asp Gln Leu Thr Ser 
                725                 730                 735     


Ser Gly Ala Pro Phe Trp Ser Gly Pro Lys Arg Cys Pro His Pro Leu 
            740                 745                 750         


Thr Phe Asp Val Asn Asn Pro Leu His Leu Asp Tyr Val Met Ala Ala 
        755                 760                 765             


Ala Asn Leu Phe Ala Gln Thr Tyr Gly Leu Thr Gly Ser Gln Asp Arg 
    770                 775                 780                 


Ala Ala Val Ala Thr Phe Leu Gln Ser Val Gln Val Pro Glu Phe Thr 
785                 790                 795                 800 


Pro Lys Ser Gly Val Lys Ile His Val Ser Asp Gln Glu Leu Gln Ser 
                805                 810                 815     


Ala Asn Ala Ser Val Asp Asp Ser Arg Leu Glu Glu Leu Lys Ala Thr 
            820                 825                 830         


Leu Pro Ser Pro Asp Lys Leu Pro Gly Phe Lys Met Tyr Pro Ile Asp 
        835                 840                 845             


Phe Glu Lys Asp Asp Asp Ser Asn Phe His Met Asp Phe Ile Val Ala 
    850                 855                 860                 


Ala Ser Asn Leu Arg Ala Glu Asn Tyr Asp Ile Pro Ser Ala Asp Arg 
865                 870                 875                 880 


His Lys Ser Lys Leu Ile Ala Gly Lys Ile Ile Pro Ala Ile Ala Thr 
                885                 890                 895     


Thr Thr Ala Ala Val Val Gly Leu Val Cys Leu Glu Leu Tyr Lys Val 
            900                 905                 910         


Val Gln Gly His Arg Gln Leu Asp Ser Tyr Lys Asn Gly Phe Leu Asn 
        915                 920                 925             


Leu Ala Leu Pro Phe Phe Gly Phe Ser Glu Pro Leu Ala Ala Pro Arg 
    930                 935                 940                 


His Gln Tyr Tyr Asn Gln Glu Trp Thr Leu Trp Asp Arg Phe Glu Val 
945                 950                 955                 960 


Gln Gly Leu Gln Pro Asn Gly Glu Glu Met Thr Leu Lys Gln Phe Leu 
                965                 970                 975     


Asp Tyr Phe Lys Thr Glu His Lys Leu Glu Ile Thr Met Leu Ser Gln 
            980                 985                 990         


Gly Val Ser Met Leu Tyr Ser Phe  Phe Met Pro Ala Ala  Lys Leu Lys 
        995                 1000                 1005             


Glu Arg  Leu Asp Gln Pro Met  Thr Glu Ile Val Ser  Arg Val Ser 
    1010                 1015                 1020             


Lys Arg  Lys Leu Gly Arg His  Val Arg Ala Leu Val  Leu Glu Leu 
    1025                 1030                 1035             


Cys Cys  Asn Asp Glu Ser Gly  Glu Asp Val Glu Val  Pro Tyr Val 
    1040                 1045                 1050             


Arg Tyr  Thr Ile Arg 
    1055             


<210>  3237
<211>  1058
<212>  PRT
<213>  homo sapiens

<400>  3237

Met Ser Ser Ser Pro Leu Ser Lys Lys Arg Arg Val Ser Gly Pro Asp 
1               5                   10                  15      


Pro Lys Pro Gly Ser Asn Cys Ser Pro Ala Gln Ser Val Leu Ser Glu 
            20                  25                  30          


Val Pro Ser Val Pro Thr Asn Gly Met Ala Lys Asn Gly Ser Glu Ala 
        35                  40                  45              


Asp Ile Asp Glu Gly Leu Tyr Ser Arg Gln Leu Tyr Val Leu Gly His 
    50                  55                  60                  


Glu Ala Met Lys Arg Leu Gln Thr Ser Ser Val Leu Val Ser Gly Leu 
65                  70                  75                  80  


Arg Gly Leu Gly Val Glu Ile Ala Lys Asn Ile Ile Leu Gly Gly Val 
                85                  90                  95      


Lys Ala Val Thr Leu His Asp Gln Gly Thr Ala Gln Trp Ala Asp Leu 
            100                 105                 110         


Ser Ser Gln Phe Tyr Leu Arg Glu Glu Asp Ile Gly Lys Asn Arg Ala 
        115                 120                 125             


Glu Val Ser Gln Pro Arg Leu Ala Glu Leu Asn Ser Tyr Val Pro Val 
    130                 135                 140                 


Thr Ala Tyr Thr Gly Pro Leu Val Glu Asp Phe Leu Ser Gly Phe Gln 
145                 150                 155                 160 


Val Val Val Leu Thr Asn Thr Pro Leu Glu Asp Gln Leu Arg Val Gly 
                165                 170                 175     


Glu Phe Cys His Asn Arg Gly Ile Lys Leu Val Val Ala Asp Thr Arg 
            180                 185                 190         


Gly Leu Phe Gly Gln Leu Phe Cys Asp Phe Gly Glu Glu Met Ile Leu 
        195                 200                 205             


Thr Asp Ser Asn Gly Glu Gln Pro Leu Ser Ala Met Val Ser Met Val 
    210                 215                 220                 


Thr Lys Asp Asn Pro Gly Val Val Thr Cys Leu Asp Glu Ala Arg His 
225                 230                 235                 240 


Gly Phe Glu Ser Gly Asp Phe Val Ser Phe Ser Glu Val Gln Gly Met 
                245                 250                 255     


Val Glu Leu Asn Gly Asn Gln Pro Met Glu Ile Lys Val Leu Gly Pro 
            260                 265                 270         


Tyr Thr Phe Ser Ile Cys Asp Thr Ser Asn Phe Ser Asp Tyr Ile Arg 
        275                 280                 285             


Gly Gly Ile Val Ser Gln Val Lys Val Pro Lys Lys Ile Ser Phe Lys 
    290                 295                 300                 


Ser Leu Val Ala Ser Leu Ala Glu Pro Asp Phe Val Val Thr Asp Phe 
305                 310                 315                 320 


Ala Lys Phe Ser Arg Pro Ala Gln Leu His Ile Gly Phe Gln Ala Leu 
                325                 330                 335     


His Gln Phe Cys Ala Gln His Gly Arg Pro Pro Arg Pro Arg Asn Glu 
            340                 345                 350         


Glu Asp Ala Ala Glu Leu Val Ala Leu Ala Gln Ala Val Asn Ala Arg 
        355                 360                 365             


Ala Leu Pro Ala Val Gln Gln Asn Asn Leu Asp Glu Asp Leu Ile Arg 
    370                 375                 380                 


Lys Leu Ala Tyr Val Ala Ala Gly Asp Leu Ala Pro Ile Asn Ala Phe 
385                 390                 395                 400 


Ile Gly Gly Leu Ala Ala Gln Glu Val Met Lys Ala Cys Ser Gly Lys 
                405                 410                 415     


Phe Met Pro Ile Met Gln Trp Leu Tyr Phe Asp Ala Leu Glu Cys Leu 
            420                 425                 430         


Pro Glu Asp Lys Glu Val Leu Thr Glu Asp Lys Cys Leu Gln Arg Gln 
        435                 440                 445             


Asn Arg Tyr Asp Gly Gln Val Ala Val Phe Gly Ser Asp Leu Gln Glu 
    450                 455                 460                 


Lys Leu Gly Lys Gln Lys Tyr Phe Leu Val Gly Ala Gly Ala Ile Gly 
465                 470                 475                 480 


Cys Glu Leu Leu Lys Asn Phe Ala Met Ile Gly Leu Gly Cys Gly Glu 
                485                 490                 495     


Gly Gly Glu Ile Ile Val Thr Asp Met Asp Thr Ile Glu Lys Ser Asn 
            500                 505                 510         


Leu Asn Arg Gln Phe Leu Phe Arg Pro Trp Asp Val Thr Lys Leu Lys 
        515                 520                 525             


Ser Asp Thr Ala Ala Ala Ala Val Arg Gln Met Asn Pro His Ile Arg 
    530                 535                 540                 


Val Thr Ser His Gln Asn Arg Val Gly Pro Asp Thr Glu Arg Ile Tyr 
545                 550                 555                 560 


Asp Asp Asp Phe Phe Gln Asn Leu Asp Gly Val Ala Asn Ala Leu Asp 
                565                 570                 575     


Asn Val Asp Ala Arg Met Tyr Met Asp Arg Arg Cys Val Tyr Tyr Arg 
            580                 585                 590         


Lys Pro Leu Leu Glu Ser Gly Thr Leu Gly Thr Lys Gly Asn Val Gln 
        595                 600                 605             


Val Val Ile Pro Phe Leu Thr Glu Ser Tyr Ser Ser Ser Gln Asp Pro 
    610                 615                 620                 


Pro Glu Lys Ser Ile Pro Ile Cys Thr Leu Lys Asn Phe Pro Asn Ala 
625                 630                 635                 640 


Ile Glu His Thr Leu Gln Trp Ala Arg Asp Glu Phe Glu Gly Leu Phe 
                645                 650                 655     


Lys Gln Pro Ala Glu Asn Val Asn Gln Tyr Leu Thr Asp Pro Lys Phe 
            660                 665                 670         


Val Glu Arg Thr Leu Arg Leu Ala Gly Thr Gln Pro Leu Glu Val Leu 
        675                 680                 685             


Glu Ala Val Gln Arg Ser Leu Val Leu Gln Arg Pro Gln Thr Trp Ala 
    690                 695                 700                 


Asp Cys Val Thr Trp Ala Cys His His Trp His Thr Gln Tyr Ser Asn 
705                 710                 715                 720 


Asn Ile Arg Gln Leu Leu His Asn Phe Pro Pro Asp Gln Leu Thr Ser 
                725                 730                 735     


Ser Gly Ala Pro Phe Trp Ser Gly Pro Lys Arg Cys Pro His Pro Leu 
            740                 745                 750         


Thr Phe Asp Val Asn Asn Pro Leu His Leu Asp Tyr Val Met Ala Ala 
        755                 760                 765             


Ala Asn Leu Phe Ala Gln Thr Tyr Gly Leu Thr Gly Ser Gln Asp Arg 
    770                 775                 780                 


Ala Ala Val Ala Thr Phe Leu Gln Ser Val Gln Val Pro Glu Phe Thr 
785                 790                 795                 800 


Pro Lys Ser Gly Val Lys Ile His Val Ser Asp Gln Glu Leu Gln Ser 
                805                 810                 815     


Ala Asn Ala Ser Val Asp Asp Ser Arg Leu Glu Glu Leu Lys Ala Thr 
            820                 825                 830         


Leu Pro Ser Pro Asp Lys Leu Pro Gly Phe Lys Met Tyr Pro Ile Asp 
        835                 840                 845             


Phe Glu Lys Asp Asp Asp Ser Asn Phe His Met Asp Phe Ile Val Ala 
    850                 855                 860                 


Ala Ser Asn Leu Arg Ala Glu Asn Tyr Asp Ile Pro Ser Ala Asp Arg 
865                 870                 875                 880 


His Lys Ser Lys Leu Ile Ala Gly Lys Ile Ile Pro Ala Ile Ala Thr 
                885                 890                 895     


Thr Thr Ala Ala Val Val Gly Leu Val Cys Leu Glu Leu Tyr Lys Val 
            900                 905                 910         


Val Gln Gly His Arg Gln Leu Asp Ser Tyr Lys Asn Gly Phe Leu Asn 
        915                 920                 925             


Leu Ala Leu Pro Phe Phe Gly Phe Ser Glu Pro Leu Ala Ala Pro Arg 
    930                 935                 940                 


His Gln Tyr Tyr Asn Gln Glu Trp Thr Leu Trp Asp Arg Phe Glu Val 
945                 950                 955                 960 


Gln Gly Leu Gln Pro Asn Gly Glu Glu Met Thr Leu Lys Gln Phe Leu 
                965                 970                 975     


Asp Tyr Phe Lys Thr Glu His Lys Leu Glu Ile Thr Met Leu Ser Gln 
            980                 985                 990         


Gly Val Ser Met Leu Tyr Ser Phe  Phe Met Pro Ala Ala  Lys Leu Lys 
        995                 1000                 1005             


Glu Arg  Leu Asp Gln Pro Met  Thr Glu Ile Val Ser  Arg Val Ser 
    1010                 1015                 1020             


Lys Arg  Lys Leu Gly Arg His  Val Arg Ala Leu Val  Leu Glu Leu 
    1025                 1030                 1035             


Cys Cys  Asn Asp Glu Ser Gly  Glu Asp Val Glu Val  Pro Tyr Val 
    1040                 1045                 1050             


Arg Tyr  Thr Ile Arg 
    1055             


<210>  3238
<211>  380
<212>  PRT
<213>  homo sapiens

<400>  3238

Met Val Gly Phe Gly Ala Asn Arg Arg Ala Gly Arg Leu Pro Ser Leu 
1               5                   10                  15      


Val Leu Val Val Leu Leu Val Val Ile Val Val Leu Ala Phe Asn Tyr 
            20                  25                  30          


Trp Ser Ile Ser Ser Arg His Val Leu Leu Gln Glu Glu Val Ala Glu 
        35                  40                  45              


Leu Gln Gly Gln Val Gln Arg Thr Glu Val Ala Arg Gly Arg Leu Glu 
    50                  55                  60                  


Lys Arg Asn Ser Asp Leu Leu Leu Leu Val Asp Thr His Lys Lys Gln 
65                  70                  75                  80  


Ile Asp Gln Lys Glu Ala Asp Tyr Gly Arg Leu Ser Ser Arg Leu Gln 
                85                  90                  95      


Ala Arg Glu Gly Leu Gly Lys Arg Cys Glu Asp Asp Lys Val Lys Leu 
            100                 105                 110         


Gln Asn Asn Ile Ser Tyr Gln Met Ala Asp Ile His His Leu Lys Glu 
        115                 120                 125             


Gln Leu Ala Glu Leu Arg Gln Glu Phe Leu Arg Gln Glu Asp Gln Leu 
    130                 135                 140                 


Gln Asp Tyr Arg Lys Asn Asn Thr Tyr Leu Val Lys Arg Leu Glu Tyr 
145                 150                 155                 160 


Glu Ser Phe Gln Cys Gly Gln Gln Met Lys Glu Leu Arg Ala Gln His 
                165                 170                 175     


Glu Glu Asn Ile Lys Lys Leu Ala Asp Gln Phe Leu Glu Glu Gln Lys 
            180                 185                 190         


Gln Glu Thr Gln Lys Ile Gln Ser Asn Asp Gly Lys Glu Leu Asp Ile 
        195                 200                 205             


Asn Asn Gln Val Val Pro Lys Asn Ile Pro Lys Val Ala Glu Asn Val 
    210                 215                 220                 


Ala Asp Lys Asn Glu Glu Pro Ser Ser Asn His Ile Pro His Gly Lys 
225                 230                 235                 240 


Glu Gln Ile Lys Arg Gly Gly Asp Ala Gly Met Pro Gly Ile Glu Glu 
                245                 250                 255     


Asn Asp Leu Ala Lys Val Asp Asp Leu Pro Pro Ala Leu Arg Lys Pro 
            260                 265                 270         


Pro Ile Ser Val Ser Gln His Glu Ser His Gln Ala Ile Ser His Leu 
        275                 280                 285             


Pro Thr Gly Gln Pro Leu Ser Pro Asn Met Pro Pro Asp Ser His Ile 
    290                 295                 300                 


Asn His Asn Gly Asn Pro Gly Thr Ser Lys Gln Asn Pro Ser Ser Pro 
305                 310                 315                 320 


Leu Gln Arg Leu Ile Pro Gly Ser Asn Leu Asp Ser Glu Pro Arg Ile 
                325                 330                 335     


Gln Thr Asp Ile Leu Lys Gln Ala Thr Lys Asp Arg Val Ser Asp Phe 
            340                 345                 350         


His Lys Leu Lys Gln Asn Asp Glu Glu Arg Glu Leu Gln Met Asp Pro 
        355                 360                 365             


Ala Asp Tyr Gly Lys Gln His Phe Asn Asp Val Leu 
    370                 375                 380 


<210>  3239
<211>  589
<212>  PRT
<213>  homo sapiens

<400>  3239

Met Asn Asn Arg Lys Glu Asp Met Glu Ile Thr Ser His Tyr Arg His 
1               5                   10                  15      


Leu Leu Arg Glu Leu Asn Glu Gln Arg Gln His Gly Val Leu Cys Asp 
            20                  25                  30          


Val Cys Val Val Val Glu Gly Lys Val Phe Lys Ala His Lys Asn Val 
        35                  40                  45              


Leu Leu Gly Ser Ser Arg Tyr Phe Lys Thr Leu Tyr Cys Gln Val Gln 
    50                  55                  60                  


Lys Thr Ser Glu Gln Ala Thr Val Thr His Leu Asp Ile Val Thr Ala 
65                  70                  75                  80  


Gln Gly Phe Lys Ala Ile Ile Asp Phe Met Tyr Ser Ala His Leu Ala 
                85                  90                  95      


Leu Thr Ser Arg Asn Val Ile Glu Val Met Ser Ala Ala Ser Phe Leu 
            100                 105                 110         


Gln Met Thr Asp Ile Val Gln Ala Cys His Asp Phe Ile Lys Ala Ala 
        115                 120                 125             


Leu Asp Ile Ser Ile Lys Ser Asp Ala Ser Asp Glu Leu Ala Glu Phe 
    130                 135                 140                 


Glu Ile Gly Ala Ser Ser Ser Ser Ser Thr Glu Ala Leu Ile Ser Ala 
145                 150                 155                 160 


Val Met Ala Gly Arg Ser Ile Ser Pro Trp Leu Ala Arg Arg Thr Ser 
                165                 170                 175     


Pro Ala Asn Ser Ser Gly Asp Ser Ala Ile Ala Ser Cys His Asp Gly 
            180                 185                 190         


Gly Ser Ser Tyr Gly Lys Glu Asp Gln Glu Pro Lys Ala Asp Gly Pro 
        195                 200                 205             


Asp Asp Val Ser Ser Gln Pro Leu Trp Pro Gly Asp Val Gly Tyr Gly 
    210                 215                 220                 


Pro Leu Arg Ile Lys Glu Glu Gln Val Ser Pro Ser Gln Tyr Gly Gly 
225                 230                 235                 240 


Ser Glu Leu Pro Ser Ala Lys Asp Gly Ala Val Gln Asn Ser Phe Ser 
                245                 250                 255     


Glu Gln Ser Ala Gly Asp Ala Trp Gln Pro Thr Gly Arg Arg Lys Asn 
            260                 265                 270         


Arg Lys Asn Lys Glu Thr Val Arg His Ile Thr Gln Gln Val Glu Asp 
        275                 280                 285             


Asp Ser Arg Ala Ser Ser Pro Val Pro Ser Phe Leu Pro Thr Ser Gly 
    290                 295                 300                 


Trp Pro Phe Ser Ser Arg Asp Ser Asn Ala Asp Leu Ser Val Thr Glu 
305                 310                 315                 320 


Ala Ser Ser Ser Asp Ser Arg Gly Glu Arg Ala Glu Leu Tyr Ala Gln 
                325                 330                 335     


Val Glu Glu Gly Leu Leu Gly Gly Glu Ala Ser Tyr Leu Gly Pro Pro 
            340                 345                 350         


Leu Thr Pro Glu Lys Asp Asp Ala Leu His Gln Ala Thr Ala Val Ala 
        355                 360                 365             


Asn Leu Arg Ala Ala Leu Met Ser Lys Asn Ser Leu Leu Ser Leu Lys 
    370                 375                 380                 


Ala Asp Val Leu Gly Asp Asp Gly Ser Leu Leu Phe Glu Tyr Leu Pro 
385                 390                 395                 400 


Arg Gly Ala His Ser Leu Ser Leu Asn Glu Phe Thr Val Ile Arg Lys 
                405                 410                 415     


Lys Phe Lys Cys Pro Tyr Cys Ser Phe Ser Ala Met His Gln Cys Ile 
            420                 425                 430         


Leu Lys Arg His Met Arg Ser His Thr Gly Glu Arg Pro Tyr Pro Cys 
        435                 440                 445             


Glu Ile Cys Gly Lys Lys Phe Thr Arg Arg Glu His Met Lys Arg His 
    450                 455                 460                 


Thr Leu Val His Ser Lys Asp Lys Lys Tyr Val Cys Lys Val Cys Ser 
465                 470                 475                 480 


Arg Val Phe Met Ser Ala Ala Ser Val Gly Ile Arg His Gly Ser Arg 
                485                 490                 495     


Arg His Gly Val Cys Thr Asp Cys Ala Gly Arg Gly Met Ala Gly Pro 
            500                 505                 510         


Leu Asp His Gly Gly Gly Gly Gly Glu Gly Ser Pro Glu Ala Leu Phe 
        515                 520                 525             


Pro Gly Asp Gly Pro Tyr Leu Glu Asp Pro Glu Asp Pro Arg Gly Glu 
    530                 535                 540                 


Ala Glu Glu Leu Gly Glu Asp Asp Glu Gly Leu Ala Pro Glu Asp Ala 
545                 550                 555                 560 


Leu Leu Ala Asp Asp Lys Asp Glu Glu Asp Ser Pro Arg Pro Arg Ser 
                565                 570                 575     


Pro Pro Gly Gly Pro Asp Lys Asp Phe Ala Trp Leu Ser 
            580                 585                 


<210>  3240
<211>  584
<212>  PRT
<213>  homo sapiens

<400>  3240

Met Ala Gly Gly Val Asp Gly Pro Ile Gly Ile Pro Phe Pro Asp His 
1               5                   10                  15      


Ser Ser Asp Ile Leu Ser Gly Leu Asn Glu Gln Arg Thr Gln Gly Leu 
            20                  25                  30          


Leu Cys Asp Val Val Ile Leu Val Glu Gly Arg Glu Phe Pro Thr His 
        35                  40                  45              


Arg Ser Val Leu Ala Ala Cys Ser Gln Tyr Phe Lys Lys Leu Phe Thr 
    50                  55                  60                  


Ser Gly Ala Val Val Asp Gln Gln Asn Val Tyr Glu Ile Asp Phe Val 
65                  70                  75                  80  


Ser Ala Glu Ala Leu Thr Ala Leu Met Asp Phe Ala Tyr Thr Ala Thr 
                85                  90                  95      


Leu Thr Val Ser Thr Ala Asn Val Gly Asp Ile Leu Ser Ala Ala Arg 
            100                 105                 110         


Leu Leu Glu Ile Pro Ala Val Ser His Val Cys Ala Asp Leu Leu Asp 
        115                 120                 125             


Arg Gln Ile Leu Ala Ala Asp Ala Gly Ala Asp Ala Gly Gln Leu Asp 
    130                 135                 140                 


Leu Val Asp Gln Ile Asp Gln Arg Asn Leu Leu Arg Ala Lys Glu Tyr 
145                 150                 155                 160 


Leu Glu Phe Phe Gln Ser Asn Pro Met Asn Ser Leu Pro Pro Ala Ala 
                165                 170                 175     


Ala Ala Ala Ala Ala Ser Phe Pro Trp Ser Ala Phe Gly Ala Ser Asp 
            180                 185                 190         


Asp Asp Leu Asp Ala Thr Lys Glu Ala Val Ala Ala Ala Val Ala Ala 
        195                 200                 205             


Val Ala Ala Gly Asp Cys Asn Gly Leu Asp Phe Tyr Gly Pro Gly Pro 
    210                 215                 220                 


Pro Ala Glu Arg Pro Pro Thr Gly Asp Gly Asp Glu Gly Asp Ser Asn 
225                 230                 235                 240 


Pro Gly Leu Trp Pro Glu Arg Asp Glu Asp Ala Pro Thr Gly Gly Leu 
                245                 250                 255     


Phe Pro Pro Pro Val Ala Pro Pro Ala Ala Thr Gln Asn Gly His Tyr 
            260                 265                 270         


Gly Arg Gly Gly Glu Glu Glu Ala Ala Ser Leu Ser Glu Ala Ala Pro 
        275                 280                 285             


Glu Pro Gly Asp Ser Pro Gly Phe Leu Ser Gly Ala Ala Glu Gly Glu 
    290                 295                 300                 


Asp Gly Asp Gly Pro Asp Val Asp Gly Leu Ala Ala Ser Thr Leu Leu 
305                 310                 315                 320 


Gln Gln Met Met Ser Ser Val Gly Arg Ala Gly Ala Ala Ala Gly Asp 
                325                 330                 335     


Ser Asp Glu Glu Ser Arg Ala Asp Asp Lys Gly Val Met Asp Tyr Tyr 
            340                 345                 350         


Leu Lys Tyr Phe Ser Gly Ala His Asp Gly Asp Val Tyr Pro Ala Trp 
        355                 360                 365             


Ser Gln Lys Val Glu Lys Lys Ile Arg Ala Lys Ala Phe Gln Lys Cys 
    370                 375                 380                 


Pro Ile Cys Glu Lys Val Ile Gln Gly Ala Gly Lys Leu Pro Arg His 
385                 390                 395                 400 


Ile Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Ile Cys Lys 
                405                 410                 415     


Val Arg Phe Thr Arg Gln Asp Lys Leu Lys Val His Met Arg Lys His 
            420                 425                 430         


Thr Gly Glu Lys Pro Tyr Leu Cys Gln Gln Cys Gly Ala Ala Phe Ala 
        435                 440                 445             


His Asn Tyr Asp Leu Lys Asn His Met Arg Val His Thr Gly Leu Arg 
    450                 455                 460                 


Pro Tyr Gln Cys Asp Ser Cys Cys Lys Thr Phe Val Arg Ser Asp His 
465                 470                 475                 480 


Leu His Arg His Leu Lys Lys Asp Gly Cys Asn Gly Val Pro Ser Arg 
                485                 490                 495     


Arg Gly Arg Lys Pro Arg Val Arg Gly Gly Ala Pro Asp Pro Ser Pro 
            500                 505                 510         


Gly Ala Thr Ala Thr Pro Gly Ala Pro Ala Gln Pro Ser Ser Pro Asp 
        515                 520                 525             


Ala Arg Arg Asn Gly Gln Glu Lys His Phe Lys Asp Glu Asp Glu Asp 
    530                 535                 540                 


Glu Asp Val Ala Ser Pro Asp Gly Leu Gly Arg Leu Asn Val Ala Gly 
545                 550                 555                 560 


Ala Gly Gly Gly Gly Asp Ser Gly Gly Gly Pro Gly Ala Ala Thr Asp 
                565                 570                 575     


Gly Asn Phe Thr Ala Gly Leu Ala 
            580                 


<210>  3241
<211>  598
<212>  PRT
<213>  homo sapiens

<400>  3241

Met Pro Cys Ile Gln Ala Gln Tyr Gly Thr Pro Ala Pro Ser Pro Gly 
1               5                   10                  15      


Pro Arg Asp His Leu Ala Ser Asp Pro Leu Thr Pro Glu Phe Ile Lys 
            20                  25                  30          


Pro Thr Met Asp Leu Ala Ser Pro Glu Ala Ala Pro Ala Ala Pro Thr 
        35                  40                  45              


Ala Leu Pro Ser Phe Ser Thr Phe Met Asp Gly Tyr Thr Gly Glu Phe 
    50                  55                  60                  


Asp Thr Phe Leu Tyr Gln Leu Pro Gly Thr Val Gln Pro Cys Ser Ser 
65                  70                  75                  80  


Ala Ser Ser Ser Ala Ser Ser Thr Ser Ser Ser Ser Ala Thr Ser Pro 
                85                  90                  95      


Ala Ser Ala Ser Phe Lys Phe Glu Asp Phe Gln Val Tyr Gly Cys Tyr 
            100                 105                 110         


Pro Gly Pro Leu Ser Gly Pro Val Asp Glu Ala Leu Ser Ser Ser Gly 
        115                 120                 125             


Ser Asp Tyr Tyr Gly Ser Pro Cys Ser Ala Pro Ser Pro Ser Thr Pro 
    130                 135                 140                 


Ser Phe Gln Pro Pro Gln Leu Ser Pro Trp Asp Gly Ser Phe Gly His 
145                 150                 155                 160 


Phe Ser Pro Ser Gln Thr Tyr Glu Gly Leu Arg Ala Trp Thr Glu Gln 
                165                 170                 175     


Leu Pro Lys Ala Ser Gly Pro Pro Gln Pro Pro Ala Phe Phe Ser Phe 
            180                 185                 190         


Ser Pro Pro Thr Gly Pro Ser Pro Ser Leu Ala Gln Ser Pro Leu Lys 
        195                 200                 205             


Leu Phe Pro Ser Gln Ala Thr His Gln Leu Gly Glu Gly Glu Ser Tyr 
    210                 215                 220                 


Ser Met Pro Thr Ala Phe Pro Gly Leu Ala Pro Thr Ser Pro His Leu 
225                 230                 235                 240 


Glu Gly Ser Gly Ile Leu Asp Thr Pro Val Thr Ser Thr Lys Ala Arg 
                245                 250                 255     


Ser Gly Ala Pro Gly Gly Ser Glu Gly Arg Cys Ala Val Cys Gly Asp 
            260                 265                 270         


Asn Ala Ser Cys Gln His Tyr Gly Val Arg Thr Cys Glu Gly Cys Lys 
        275                 280                 285             


Gly Phe Phe Lys Arg Thr Val Gln Lys Asn Ala Lys Tyr Ile Cys Leu 
    290                 295                 300                 


Ala Asn Lys Asp Cys Pro Val Asp Lys Arg Arg Arg Asn Arg Cys Gln 
305                 310                 315                 320 


Phe Cys Arg Phe Gln Lys Cys Leu Ala Val Gly Met Val Lys Glu Val 
                325                 330                 335     


Val Arg Thr Asp Ser Leu Lys Gly Arg Arg Gly Arg Leu Pro Ser Lys 
            340                 345                 350         


Pro Lys Gln Pro Pro Asp Ala Ser Pro Ala Asn Leu Leu Thr Ser Leu 
        355                 360                 365             


Val Arg Ala His Leu Asp Ser Gly Pro Ser Thr Ala Lys Leu Asp Tyr 
    370                 375                 380                 


Ser Lys Phe Gln Glu Leu Val Leu Pro His Phe Gly Lys Glu Asp Ala 
385                 390                 395                 400 


Gly Asp Val Gln Gln Phe Tyr Asp Leu Leu Ser Gly Ser Leu Glu Val 
                405                 410                 415     


Ile Arg Lys Trp Ala Glu Lys Ile Pro Gly Phe Ala Glu Leu Ser Pro 
            420                 425                 430         


Ala Asp Gln Asp Leu Leu Leu Glu Ser Ala Phe Leu Glu Leu Phe Ile 
        435                 440                 445             


Leu Arg Leu Ala Tyr Arg Ser Lys Pro Gly Glu Gly Lys Leu Ile Phe 
    450                 455                 460                 


Cys Ser Gly Leu Val Leu His Arg Leu Gln Cys Ala Arg Gly Phe Gly 
465                 470                 475                 480 


Asp Trp Ile Asp Ser Ile Leu Ala Phe Ser Arg Ser Leu His Ser Leu 
                485                 490                 495     


Leu Val Asp Val Pro Ala Phe Ala Cys Leu Ser Ala Leu Val Leu Ile 
            500                 505                 510         


Thr Asp Arg His Gly Leu Gln Glu Pro Arg Arg Val Glu Glu Leu Gln 
        515                 520                 525             


Asn Arg Ile Ala Ser Cys Leu Lys Glu His Val Ala Ala Val Ala Gly 
    530                 535                 540                 


Glu Pro Gln Pro Ala Ser Cys Leu Ser Arg Leu Leu Gly Lys Leu Pro 
545                 550                 555                 560 


Glu Leu Arg Thr Leu Cys Thr Gln Gly Leu Gln Arg Ile Phe Tyr Leu 
                565                 570                 575     


Lys Leu Glu Asp Leu Val Pro Pro Pro Pro Ile Ile Asp Lys Ile Phe 
            580                 585                 590         


Met Asp Thr Leu Pro Phe 
        595             


<210>  3242
<211>  598
<212>  PRT
<213>  homo sapiens

<400>  3242

Met Pro Cys Val Gln Ala Gln Tyr Gly Ser Ser Pro Gln Gly Ala Ser 
1               5                   10                  15      


Pro Ala Ser Gln Ser Tyr Ser Tyr His Ser Ser Gly Glu Tyr Ser Ser 
            20                  25                  30          


Asp Phe Leu Thr Pro Glu Phe Val Lys Phe Ser Met Asp Leu Thr Asn 
        35                  40                  45              


Thr Glu Ile Thr Ala Thr Thr Ser Leu Pro Ser Phe Ser Thr Phe Met 
    50                  55                  60                  


Asp Asn Tyr Ser Thr Gly Tyr Asp Val Lys Pro Pro Cys Leu Tyr Gln 
65                  70                  75                  80  


Met Pro Leu Ser Gly Gln Gln Ser Ser Ile Lys Val Glu Asp Ile Gln 
                85                  90                  95      


Met His Asn Tyr Gln Gln His Ser His Leu Pro Pro Gln Ser Glu Glu 
            100                 105                 110         


Met Met Pro His Ser Gly Ser Val Tyr Tyr Lys Pro Ser Ser Pro Pro 
        115                 120                 125             


Thr Pro Thr Thr Pro Gly Phe Gln Val Gln His Ser Pro Met Trp Asp 
    130                 135                 140                 


Asp Pro Gly Ser Leu His Asn Phe His Gln Asn Tyr Val Ala Thr Thr 
145                 150                 155                 160 


His Met Ile Glu Gln Arg Lys Thr Pro Val Ser Arg Leu Ser Leu Phe 
                165                 170                 175     


Ser Phe Lys Gln Ser Pro Pro Gly Thr Pro Val Ser Ser Cys Gln Met 
            180                 185                 190         


Arg Phe Asp Gly Pro Leu His Val Pro Met Asn Pro Glu Pro Ala Gly 
        195                 200                 205             


Ser His His Val Val Asp Gly Gln Thr Phe Ala Val Pro Asn Pro Ile 
    210                 215                 220                 


Arg Lys Pro Ala Ser Met Gly Phe Pro Gly Leu Gln Ile Gly His Ala 
225                 230                 235                 240 


Ser Gln Leu Leu Asp Thr Gln Val Pro Ser Pro Pro Ser Arg Gly Ser 
                245                 250                 255     


Pro Ser Asn Glu Gly Leu Cys Ala Val Cys Gly Asp Asn Ala Ala Cys 
            260                 265                 270         


Gln His Tyr Gly Val Arg Thr Cys Glu Gly Cys Lys Gly Phe Phe Lys 
        275                 280                 285             


Arg Thr Val Gln Lys Asn Ala Lys Tyr Val Cys Leu Ala Asn Lys Asn 
    290                 295                 300                 


Cys Pro Val Asp Lys Arg Arg Arg Asn Arg Cys Gln Tyr Cys Arg Phe 
305                 310                 315                 320 


Gln Lys Cys Leu Ala Val Gly Met Val Lys Glu Val Val Arg Thr Asp 
                325                 330                 335     


Ser Leu Lys Gly Arg Arg Gly Arg Leu Pro Ser Lys Pro Lys Ser Pro 
            340                 345                 350         


Gln Glu Pro Ser Pro Pro Ser Pro Pro Val Ser Leu Ile Ser Ala Leu 
        355                 360                 365             


Val Arg Ala His Val Asp Ser Asn Pro Ala Met Thr Ser Leu Asp Tyr 
    370                 375                 380                 


Ser Arg Phe Gln Ala Asn Pro Asp Tyr Gln Met Ser Gly Asp Asp Thr 
385                 390                 395                 400 


Gln His Ile Gln Gln Phe Tyr Asp Leu Leu Thr Gly Ser Met Glu Ile 
                405                 410                 415     


Ile Arg Gly Trp Ala Glu Lys Ile Pro Gly Phe Ala Asp Leu Pro Lys 
            420                 425                 430         


Ala Asp Gln Asp Leu Leu Phe Glu Ser Ala Phe Leu Glu Leu Phe Val 
        435                 440                 445             


Leu Arg Leu Ala Tyr Arg Ser Asn Pro Val Glu Gly Lys Leu Ile Phe 
    450                 455                 460                 


Cys Asn Gly Val Val Leu His Arg Leu Gln Cys Val Arg Gly Phe Gly 
465                 470                 475                 480 


Glu Trp Ile Asp Ser Ile Val Glu Phe Ser Ser Asn Leu Gln Asn Met 
                485                 490                 495     


Asn Ile Asp Ile Ser Ala Phe Ser Cys Ile Ala Ala Leu Ala Met Val 
            500                 505                 510         


Thr Glu Arg His Gly Leu Lys Glu Pro Lys Arg Val Glu Glu Leu Gln 
        515                 520                 525             


Asn Lys Ile Val Asn Cys Leu Lys Asp His Val Thr Phe Asn Asn Gly 
    530                 535                 540                 


Gly Leu Asn Arg Pro Asn Tyr Leu Ser Lys Leu Leu Gly Lys Leu Pro 
545                 550                 555                 560 


Glu Leu Arg Thr Leu Cys Thr Gln Gly Leu Gln Arg Ile Phe Tyr Leu 
                565                 570                 575     


Lys Leu Glu Asp Leu Val Pro Pro Pro Ala Ile Ile Asp Lys Leu Phe 
            580                 585                 590         


Leu Asp Thr Leu Pro Phe 
        595             


<210>  3243
<211>  440
<212>  PRT
<213>  homo sapiens

<400>  3243

Met Gly Ser Ser His Leu Leu Asn Lys Gly Leu Pro Leu Gly Val Arg 
1               5                   10                  15      


Pro Pro Ile Met Asn Gly Pro Leu His Pro Arg Pro Leu Val Ala Leu 
            20                  25                  30          


Leu Asp Gly Arg Asp Cys Thr Val Glu Met Pro Ile Leu Lys Asp Val 
        35                  40                  45              


Ala Thr Val Ala Phe Cys Asp Ala Gln Ser Thr Gln Glu Ile His Glu 
    50                  55                  60                  


Lys Val Leu Asn Glu Ala Val Gly Ala Leu Met Tyr His Thr Ile Thr 
65                  70                  75                  80  


Leu Thr Arg Glu Asp Leu Glu Lys Phe Lys Ala Leu Arg Ile Ile Val 
                85                  90                  95      


Arg Ile Gly Ser Gly Phe Asp Asn Ile Asp Ile Lys Ser Ala Gly Asp 
            100                 105                 110         


Leu Gly Ile Ala Val Cys Asn Val Pro Ala Ala Ser Val Glu Glu Thr 
        115                 120                 125             


Ala Asp Ser Thr Leu Cys His Ile Leu Asn Leu Tyr Arg Arg Ala Thr 
    130                 135                 140                 


Trp Leu His Gln Ala Leu Arg Glu Gly Thr Arg Val Gln Ser Val Glu 
145                 150                 155                 160 


Gln Ile Arg Glu Val Ala Ser Gly Ala Ala Arg Ile Arg Gly Glu Thr 
                165                 170                 175     


Leu Gly Ile Ile Gly Leu Gly Arg Val Gly Gln Ala Val Ala Leu Arg 
            180                 185                 190         


Ala Lys Ala Phe Gly Phe Asn Val Leu Phe Tyr Asp Pro Tyr Leu Ser 
        195                 200                 205             


Asp Gly Val Glu Arg Ala Leu Gly Leu Gln Arg Val Ser Thr Leu Gln 
    210                 215                 220                 


Asp Leu Leu Phe His Ser Asp Cys Val Thr Leu His Cys Gly Leu Asn 
225                 230                 235                 240 


Glu His Asn His His Leu Ile Asn Asp Phe Thr Val Lys Gln Met Arg 
                245                 250                 255     


Gln Gly Ala Phe Leu Val Asn Thr Ala Arg Gly Gly Leu Val Asp Glu 
            260                 265                 270         


Lys Ala Leu Ala Gln Ala Leu Lys Glu Gly Arg Ile Arg Gly Ala Ala 
        275                 280                 285             


Leu Asp Val His Glu Ser Glu Pro Phe Ser Phe Ser Gln Gly Pro Leu 
    290                 295                 300                 


Lys Asp Ala Pro Asn Leu Ile Cys Thr Pro His Ala Ala Trp Tyr Ser 
305                 310                 315                 320 


Glu Gln Ala Ser Ile Glu Met Arg Glu Glu Ala Ala Arg Glu Ile Arg 
                325                 330                 335     


Arg Ala Ile Thr Gly Arg Ile Pro Asp Ser Leu Lys Asn Cys Val Asn 
            340                 345                 350         


Lys Asp His Leu Thr Ala Ala Thr His Trp Ala Ser Met Asp Pro Ala 
        355                 360                 365             


Val Val His Pro Glu Leu Asn Gly Ala Ala Tyr Arg Tyr Pro Pro Gly 
    370                 375                 380                 


Val Val Gly Val Ala Pro Thr Gly Ile Pro Ala Ala Val Glu Gly Ile 
385                 390                 395                 400 


Val Pro Ser Ala Met Ser Leu Ser His Gly Leu Pro Pro Val Ala His 
                405                 410                 415     


Pro Pro His Ala Pro Ser Pro Gly Gln Thr Val Lys Pro Glu Ala Asp 
            420                 425                 430         


Arg Asp His Ala Ser Asp Gln Leu 
        435                 440 


<210>  3244
<211>  132
<212>  PRT
<213>  homo sapiens

<400>  3244

Met Val Glu Ala Phe Cys Ala Thr Trp Lys Leu Thr Asn Ser Gln Asn 
1               5                   10                  15      


Phe Asp Glu Tyr Met Lys Ala Leu Gly Val Gly Phe Ala Thr Arg Gln 
            20                  25                  30          


Val Gly Asn Val Thr Lys Pro Thr Val Ile Ile Ser Gln Glu Gly Asp 
        35                  40                  45              


Lys Val Val Ile Arg Thr Leu Ser Thr Phe Lys Asn Thr Glu Ile Ser 
    50                  55                  60                  


Phe Gln Leu Gly Glu Glu Phe Asp Glu Thr Thr Ala Asp Asp Arg Asn 
65                  70                  75                  80  


Cys Lys Ser Val Val Ser Leu Asp Gly Asp Lys Leu Val His Ile Gln 
                85                  90                  95      


Lys Trp Asp Gly Lys Glu Thr Asn Phe Val Arg Glu Ile Lys Asp Gly 
            100                 105                 110         


Lys Met Val Met Thr Leu Thr Phe Gly Asp Val Val Ala Val Arg His 
        115                 120                 125             


Tyr Glu Lys Ala 
    130         


<210>  3245
<211>  302
<212>  PRT
<213>  homo sapiens

<400>  3245

Met Cys Ala Glu Arg Leu Gly Gln Phe Met Thr Leu Ala Leu Val Leu 
1               5                   10                  15      


Ala Thr Phe Asp Pro Ala Arg Gly Thr Asp Ala Thr Asn Pro Pro Glu 
            20                  25                  30          


Gly Pro Gln Asp Arg Ser Ser Gln Gln Lys Gly Arg Leu Ser Leu Gln 
        35                  40                  45              


Asn Thr Ala Glu Ile Gln His Cys Leu Val Asn Ala Gly Asp Val Gly 
    50                  55                  60                  


Cys Gly Val Phe Glu Cys Phe Glu Asn Asn Ser Cys Glu Ile Arg Gly 
65                  70                  75                  80  


Leu His Gly Ile Cys Met Thr Phe Leu His Asn Ala Gly Lys Phe Asp 
                85                  90                  95      


Ala Gln Gly Lys Ser Phe Ile Lys Asp Ala Leu Lys Cys Lys Ala His 
            100                 105                 110         


Ala Leu Arg His Arg Phe Gly Cys Ile Ser Arg Lys Cys Pro Ala Ile 
        115                 120                 125             


Arg Glu Met Val Ser Gln Leu Gln Arg Glu Cys Tyr Leu Lys His Asp 
    130                 135                 140                 


Leu Cys Ala Ala Ala Gln Glu Asn Thr Arg Val Ile Val Glu Met Ile 
145                 150                 155                 160 


His Phe Lys Asp Leu Leu Leu His Glu Pro Tyr Val Asp Leu Val Asn 
                165                 170                 175     


Leu Leu Leu Thr Cys Gly Glu Glu Val Lys Glu Ala Ile Thr His Ser 
            180                 185                 190         


Val Gln Val Gln Cys Glu Gln Asn Trp Gly Ser Leu Cys Ser Ile Leu 
        195                 200                 205             


Ser Phe Cys Thr Ser Ala Ile Gln Lys Pro Pro Thr Ala Pro Pro Glu 
    210                 215                 220                 


Arg Gln Pro Gln Val Asp Arg Thr Lys Leu Ser Arg Ala His His Gly 
225                 230                 235                 240 


Glu Ala Gly His His Leu Pro Glu Pro Ser Ser Arg Glu Thr Gly Arg 
                245                 250                 255     


Gly Ala Lys Gly Glu Arg Gly Ser Lys Ser His Pro Asn Ala His Ala 
            260                 265                 270         


Arg Gly Arg Val Gly Gly Leu Gly Ala Gln Gly Pro Ser Gly Ser Ser 
        275                 280                 285             


Glu Trp Glu Asp Glu Gln Ser Glu Tyr Ser Asp Ile Arg Arg 
    290                 295                 300         


<210>  3246
<211>  684
<212>  PRT
<213>  homo sapiens

<400>  3246

Met Ser Ser Glu Cys Asp Gly Gly Ser Lys Ala Val Met Asn Gly Leu 
1               5                   10                  15      


Ala Pro Gly Ser Asn Gly Gln Asp Lys Asp Met Asp Pro Thr Lys Ile 
            20                  25                  30          


Cys Thr Gly Lys Gly Ala Val Thr Leu Arg Ala Ser Ser Ser Tyr Arg 
        35                  40                  45              


Glu Thr Pro Ser Ser Ser Pro Ala Ser Pro Gln Glu Thr Arg Gln His 
    50                  55                  60                  


Glu Ser Lys Pro Asp Glu Trp Arg Leu Ser Ser Ser Ala Asp Ala Asn 
65                  70                  75                  80  


Gly Asn Ala Gln Pro Ser Ser Leu Ala Ala Lys Gly Tyr Arg Ser Val 
                85                  90                  95      


His Pro Asn Leu Pro Ser Asp Lys Ser Gln Asp Ser Ser Pro Leu Leu 
            100                 105                 110         


Asn Glu Val Ser Ser Ser Leu Ile Gly Thr Asp Ser Gln Ala Phe Pro 
        115                 120                 125             


Ser Val Ser Lys Pro Ser Ser Ala Tyr Pro Ser Thr Thr Ile Val Asn 
    130                 135                 140                 


Pro Thr Ile Val Leu Leu Gln His Asn Arg Glu Gln Gln Lys Arg Leu 
145                 150                 155                 160 


Ser Ser Leu Ser Asp Pro Val Ser Glu Arg Arg Val Gly Glu Gln Asp 
                165                 170                 175     


Ser Ala Pro Thr Gln Glu Lys Pro Thr Ser Pro Gly Lys Ala Ile Glu 
            180                 185                 190         


Lys Arg Ala Lys Asp Asp Ser Arg Arg Val Val Lys Ser Thr Gln Asp 
        195                 200                 205             


Leu Ser Asp Val Ser Met Asp Glu Val Gly Ile Pro Leu Arg Asn Thr 
    210                 215                 220                 


Glu Arg Ser Lys Asp Trp Tyr Lys Thr Met Phe Lys Gln Ile His Lys 
225                 230                 235                 240 


Leu Asn Arg Asp Asp Asp Ser Asp Leu Tyr Ser Pro Arg Tyr Ser Phe 
                245                 250                 255     


Ser Glu Asp Thr Lys Ser Pro Leu Ser Val Pro Arg Ser Lys Ser Glu 
            260                 265                 270         


Met Ser Tyr Ile Asp Gly Glu Lys Val Val Lys Arg Ser Ala Thr Leu 
        275                 280                 285             


Pro Leu Pro Ala Arg Ser Ser Ser Leu Lys Ser Ser Ser Glu Arg Asn 
    290                 295                 300                 


Asp Trp Glu Pro Pro Asp Lys Lys Val Asp Thr Arg Lys Tyr Arg Ala 
305                 310                 315                 320 


Glu Pro Lys Ser Ile Tyr Glu Tyr Gln Pro Gly Lys Ser Ser Val Leu 
                325                 330                 335     


Thr Asn Glu Lys Met Ser Ser Ala Ile Ser Pro Thr Pro Glu Ile Ser 
            340                 345                 350         


Ser Glu Thr Pro Gly Tyr Ile Tyr Ser Ser Asn Phe His Ala Val Lys 
        355                 360                 365             


Arg Glu Ser Asp Gly Ala Pro Gly Asp Leu Thr Ser Leu Glu Asn Glu 
    370                 375                 380                 


Arg Gln Ile Tyr Lys Ser Val Leu Glu Gly Gly Asp Ile Pro Leu Gln 
385                 390                 395                 400 


Gly Leu Ser Gly Leu Lys Arg Pro Ser Ser Ser Ala Ser Thr Lys Asp 
                405                 410                 415     


Ser Glu Ser Pro Arg His Phe Ile Pro Ala Asp Tyr Leu Glu Ser Thr 
            420                 425                 430         


Glu Glu Phe Ile Arg Arg Arg His Asp Asp Lys Glu Met Arg Pro Ala 
        435                 440                 445             


Arg Ala Lys Phe Asp Phe Lys Ala Gln Thr Leu Lys Glu Leu Pro Leu 
    450                 455                 460                 


Gln Lys Gly Asp Ile Val Tyr Ile Tyr Lys Gln Ile Asp Gln Asn Trp 
465                 470                 475                 480 


Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe Pro Arg Thr Tyr 
                485                 490                 495     


Ile Glu Leu Leu Pro Pro Ala Glu Lys Ala Gln Pro Lys Lys Leu Thr 
            500                 505                 510         


Pro Val Gln Val Leu Glu Tyr Gly Glu Ala Ile Ala Lys Phe Asn Phe 
        515                 520                 525             


Asn Gly Asp Thr Gln Val Glu Met Ser Phe Arg Lys Gly Glu Arg Ile 
    530                 535                 540                 


Thr Leu Leu Arg Gln Val Asp Glu Asn Trp Tyr Glu Gly Arg Ile Pro 
545                 550                 555                 560 


Gly Thr Ser Arg Gln Gly Ile Phe Pro Ile Thr Tyr Val Asp Val Ile 
                565                 570                 575     


Lys Arg Pro Leu Val Lys Asn Pro Val Asp Tyr Met Asp Leu Pro Phe 
            580                 585                 590         


Ser Ser Ser Pro Ser Arg Ser Ala Thr Ala Ser Pro Gln Gln Pro Gln 
        595                 600                 605             


Ala Gln Gln Arg Arg Val Thr Pro Asp Arg Ser Gln Thr Ser Gln Asp 
    610                 615                 620                 


Leu Phe Ser Tyr Gln Ala Leu Tyr Ser Tyr Ile Pro Gln Asn Asp Asp 
625                 630                 635                 640 


Glu Leu Glu Leu Arg Asp Gly Asp Ile Val Asp Val Met Glu Lys Cys 
                645                 650                 655     


Asp Asp Gly Trp Phe Val Gly Thr Ser Arg Arg Thr Lys Gln Phe Gly 
            660                 665                 670         


Thr Phe Pro Gly Asn Tyr Val Lys Pro Leu Tyr Leu 
        675                 680                 


<210>  3247
<211>  79
<212>  PRT
<213>  homo sapiens

<400>  3247

Met Ser His Lys Gln Ile Tyr Tyr Ser Asp Lys Tyr Asp Asp Glu Glu 
1               5                   10                  15      


Phe Glu Tyr Arg His Val Met Leu Pro Lys Asp Ile Ala Lys Leu Val 
            20                  25                  30          


Pro Lys Thr His Leu Met Ser Glu Ser Glu Trp Arg Asn Leu Gly Val 
        35                  40                  45              


Gln Gln Ser Gln Gly Trp Val His Tyr Met Ile His Glu Pro Glu Pro 
    50                  55                  60                  


His Ile Leu Leu Phe Arg Arg Pro Leu Pro Lys Lys Pro Lys Lys 
65                  70                  75                  


<210>  3248
<211>  442
<212>  PRT
<213>  homo sapiens

<400>  3248

Met Lys Pro Gly Pro Pro His Arg Ala Gly Ala Ala His Gly Ala Gly 
1               5                   10                  15      


Ala Gly Ala Gly Ala Ala Ala Gly Pro Gly Ala Arg Gly Leu Leu Leu 
            20                  25                  30          


Pro Pro Leu Leu Leu Leu Leu Leu Ala Gly Arg Ala Ala Gly Ala Gln 
        35                  40                  45              


Arg Trp Arg Ser Glu Asn Phe Glu Arg Pro Val Asp Leu Glu Gly Ser 
    50                  55                  60                  


Gly Asp Asp Asp Ser Phe Pro Asp Asp Glu Leu Asp Asp Leu Tyr Ser 
65                  70                  75                  80  


Gly Ser Gly Ser Gly Tyr Phe Glu Gln Glu Ser Gly Ile Glu Thr Ala 
                85                  90                  95      


Met Arg Phe Ser Pro Asp Val Ala Leu Ala Val Ser Thr Thr Pro Ala 
            100                 105                 110         


Val Leu Pro Thr Thr Asn Ile Gln Pro Val Gly Thr Pro Phe Glu Glu 
        115                 120                 125             


Leu Pro Ser Glu Arg Pro Thr Leu Glu Pro Ala Thr Ser Pro Leu Val 
    130                 135                 140                 


Val Thr Glu Val Pro Glu Glu Pro Ser Gln Arg Ala Thr Thr Val Ser 
145                 150                 155                 160 


Thr Thr Met Ala Thr Thr Ala Ala Thr Ser Thr Gly Asp Pro Thr Val 
                165                 170                 175     


Ala Thr Val Pro Ala Thr Val Ala Thr Ala Thr Pro Ser Thr Pro Ala 
            180                 185                 190         


Ala Pro Pro Phe Thr Ala Thr Thr Ala Val Ile Arg Thr Thr Gly Val 
        195                 200                 205             


Arg Arg Leu Leu Pro Leu Pro Leu Thr Thr Val Ala Thr Ala Arg Ala 
    210                 215                 220                 


Thr Thr Pro Glu Ala Pro Ser Pro Pro Thr Thr Ala Ala Val Leu Asp 
225                 230                 235                 240 


Thr Glu Ala Pro Thr Pro Arg Leu Val Ser Thr Ala Thr Ser Arg Pro 
                245                 250                 255     


Arg Ala Leu Pro Arg Pro Ala Thr Thr Gln Glu Pro Asp Ile Pro Glu 
            260                 265                 270         


Arg Ser Thr Leu Pro Leu Gly Thr Thr Ala Pro Gly Pro Thr Glu Val 
        275                 280                 285             


Ala Gln Thr Pro Thr Pro Glu Thr Phe Leu Thr Thr Ile Arg Asp Glu 
    290                 295                 300                 


Pro Glu Val Pro Val Ser Gly Gly Pro Ser Gly Asp Phe Glu Leu Pro 
305                 310                 315                 320 


Glu Glu Glu Thr Thr Gln Pro Asp Thr Ala Asn Glu Val Val Ala Val 
                325                 330                 335     


Gly Gly Ala Ala Ala Lys Ala Ser Ser Pro Pro Gly Thr Leu Pro Lys 
            340                 345                 350         


Gly Ala Arg Pro Gly Pro Gly Leu Leu Asp Asn Ala Ile Asp Ser Gly 
        355                 360                 365             


Ser Ser Ala Ala Gln Leu Pro Gln Lys Ser Ile Leu Glu Arg Lys Glu 
    370                 375                 380                 


Val Leu Val Ala Val Ile Val Gly Gly Val Val Gly Ala Leu Phe Ala 
385                 390                 395                 400 


Ala Phe Leu Val Thr Leu Leu Ile Tyr Arg Met Lys Lys Lys Asp Glu 
                405                 410                 415     


Gly Ser Tyr Thr Leu Glu Glu Pro Lys Gln Ala Ser Val Thr Tyr Gln 
            420                 425                 430         


Lys Pro Asp Lys Gln Glu Glu Phe Tyr Ala 
        435                 440         


<210>  3249
<211>  2172
<212>  PRT
<213>  homo sapiens

<400>  3249

Met Trp Gly Leu Leu Ile Trp Thr Leu Leu Ala Leu His Gln Ile Arg 
1               5                   10                  15      


Ala Ala Arg Ala Gln Asp Asp Val Ser Pro Tyr Phe Lys Thr Glu Pro 
            20                  25                  30          


Val Arg Thr Gln Val His Leu Glu Gly Asn Arg Leu Val Leu Thr Cys 
        35                  40                  45              


Met Ala Glu Gly Ser Trp Pro Leu Glu Phe Lys Trp Leu His Asn Asn 
    50                  55                  60                  


Arg Glu Leu Thr Lys Phe Ser Leu Glu Tyr Arg Tyr Met Ile Thr Ser 
65                  70                  75                  80  


Leu Asp Arg Thr His Ala Gly Phe Tyr Arg Cys Ile Val Arg Asn Arg 
                85                  90                  95      


Met Gly Ala Leu Leu Gln Arg Gln Thr Glu Val Gln Val Ala Tyr Met 
            100                 105                 110         


Gly Ser Phe Glu Glu Gly Glu Lys His Gln Ser Val Ser His Gly Glu 
        115                 120                 125             


Ala Ala Val Ile Arg Ala Pro Arg Ile Ala Ser Phe Pro Gln Pro Gln 
    130                 135                 140                 


Val Thr Trp Phe Arg Asp Gly Arg Lys Ile Pro Pro Ser Ser Arg Ile 
145                 150                 155                 160 


Ala Ile Thr Leu Glu Asn Thr Leu Val Ile Leu Ser Thr Val Ala Pro 
                165                 170                 175     


Asp Ala Gly Arg Tyr Tyr Val Gln Ala Val Asn Asp Lys Asn Gly Asp 
            180                 185                 190         


Asn Lys Thr Ser Gln Pro Ile Thr Leu Thr Val Glu Asn Val Gly Gly 
        195                 200                 205             


Pro Ala Asp Pro Ile Ala Pro Thr Ile Ile Ile Pro Pro Lys Asn Thr 
    210                 215                 220                 


Ser Val Val Ala Gly Thr Ser Glu Val Thr Leu Glu Cys Val Ala Asn 
225                 230                 235                 240 


Ala Arg Pro Leu Ile Lys Leu His Ile Ile Trp Lys Lys Asp Gly Val 
                245                 250                 255     


Leu Leu Ser Gly Gly Ile Ser Asp His Asn Arg Arg Leu Thr Ile Pro 
            260                 265                 270         


Asn Pro Thr Gly Ser Asp Ala Gly Tyr Tyr Glu Cys Glu Ala Val Leu 
        275                 280                 285             


Arg Ser Ser Ser Val Pro Ser Val Val Arg Gly Ala Tyr Leu Ser Val 
    290                 295                 300                 


Leu Glu Pro Pro Gln Phe Val Lys Glu Pro Glu Arg His Ile Thr Ala 
305                 310                 315                 320 


Glu Met Glu Lys Val Val Asp Ile Pro Cys Gln Ala Lys Gly Val Pro 
                325                 330                 335     


Pro Pro Ser Ile Thr Trp Tyr Lys Asp Ala Ala Val Val Glu Val Glu 
            340                 345                 350         


Lys Leu Thr Arg Phe Arg Gln Arg Asn Asp Gly Gly Leu Gln Ile Ser 
        355                 360                 365             


Gly Leu Val Pro Asp Asp Thr Gly Met Phe Gln Cys Phe Ala Arg Asn 
    370                 375                 380                 


Ala Ala Gly Glu Val Gln Thr Ser Thr Tyr Leu Ala Val Thr Ser Ile 
385                 390                 395                 400 


Ala Pro Asn Ile Thr Arg Gly Pro Leu Asp Ser Thr Val Ile Asp Gly 
                405                 410                 415     


Met Ser Val Val Leu Ala Cys Glu Thr Ser Gly Ala Pro Arg Pro Ala 
            420                 425                 430         


Ile Thr Trp Gln Lys Gly Glu Arg Ile Leu Ala Ser Gly Ser Val Gln 
        435                 440                 445             


Leu Pro Arg Phe Thr Pro Leu Glu Ser Gly Ser Leu Leu Ile Ser Pro 
    450                 455                 460                 


Thr His Ile Ser Asp Ala Gly Thr Tyr Thr Cys Leu Ala Thr Asn Ser 
465                 470                 475                 480 


Arg Gly Val Asp Glu Ala Ser Ala Asp Leu Val Val Trp Ala Arg Thr 
                485                 490                 495     


Arg Ile Thr Lys Pro Pro Gln Asp Gln Ser Val Ile Lys Gly Thr Gln 
            500                 505                 510         


Ala Ser Met Val Cys Gly Val Thr His Asp Pro Arg Val Thr Ile Arg 
        515                 520                 525             


Tyr Ile Trp Glu Lys Asp Gly Ala Thr Leu Gly Thr Glu Ser His Pro 
    530                 535                 540                 


Arg Ile Arg Leu Asp Arg Asn Gly Ser Leu His Ile Ser Gln Thr Trp 
545                 550                 555                 560 


Ser Gly Asp Ile Gly Thr Tyr Thr Cys Arg Val Ile Ser Ala Gly Gly 
                565                 570                 575     


Asn Asp Ser Arg Ser Ala His Leu Arg Val Arg Gln Leu Pro His Ala 
            580                 585                 590         


Pro Glu His Pro Val Ala Thr Leu Ser Thr Val Glu Arg Arg Ala Ile 
        595                 600                 605             


Asn Leu Thr Trp Thr Lys Pro Phe Asp Gly Asn Ser Pro Leu Ile Arg 
    610                 615                 620                 


Tyr Ile Leu Glu Met Ser Glu Asn Asn Ala Pro Trp Thr Val Leu Leu 
625                 630                 635                 640 


Ala Ser Val Asp Pro Lys Ala Thr Ser Val Thr Val Lys Gly Leu Val 
                645                 650                 655     


Pro Ala Arg Ser Tyr Gln Phe Arg Leu Cys Ala Val Asn Asp Val Gly 
            660                 665                 670         


Lys Gly Gln Phe Ser Lys Asp Thr Glu Arg Val Ser Leu Pro Glu Glu 
        675                 680                 685             


Pro Pro Thr Ala Pro Pro Gln Asn Val Ile Ala Ser Gly Arg Thr Asn 
    690                 695                 700                 


Gln Ser Ile Met Ile Gln Trp Gln Pro Pro Pro Glu Ser His Gln Asn 
705                 710                 715                 720 


Gly Ile Leu Lys Gly Tyr Ile Ile Arg Tyr Cys Leu Ala Gly Leu Pro 
                725                 730                 735     


Val Gly Tyr Gln Phe Lys Asn Ile Thr Asp Ala Asp Val Asn Asn Leu 
            740                 745                 750         


Leu Leu Glu Asp Leu Ile Ile Trp Thr Asn Tyr Glu Ile Glu Val Ala 
        755                 760                 765             


Ala Tyr Asn Ser Ala Gly Leu Gly Val Tyr Ser Ser Lys Val Thr Glu 
    770                 775                 780                 


Trp Thr Leu Gln Gly Val Pro Thr Val Pro Pro Gly Asn Val His Ala 
785                 790                 795                 800 


Glu Ala Thr Asn Ser Thr Thr Ile Arg Phe Thr Trp Asn Ala Pro Ser 
                805                 810                 815     


Pro Gln Phe Ile Asn Gly Ile Asn Gln Gly Tyr Lys Leu Ile Ala Trp 
            820                 825                 830         


Glu Pro Glu Gln Glu Glu Glu Val Thr Met Val Thr Ala Arg Pro Asn 
        835                 840                 845             


Phe Gln Asp Ser Ile His Val Gly Phe Val Ser Gly Leu Lys Lys Phe 
    850                 855                 860                 


Thr Glu Tyr Phe Thr Ser Val Leu Cys Phe Thr Thr Pro Gly Asp Gly 
865                 870                 875                 880 


Pro Arg Ser Thr Pro Gln Leu Val Arg Thr His Glu Asp Val Pro Gly 
                885                 890                 895     


Pro Val Gly His Leu Ser Phe Ser Glu Ile Leu Asp Thr Ser Leu Lys 
            900                 905                 910         


Val Ser Trp Gln Glu Pro Gly Glu Lys Asn Gly Ile Leu Thr Gly Tyr 
        915                 920                 925             


Arg Ile Ser Trp Glu Glu Tyr Asn Arg Thr Asn Thr Arg Val Thr His 
    930                 935                 940                 


Tyr Leu Pro Asn Val Thr Leu Glu Tyr Arg Val Thr Gly Leu Thr Ala 
945                 950                 955                 960 


Leu Thr Thr Tyr Thr Ile Glu Val Ala Ala Met Thr Ser Lys Gly Gln 
                965                 970                 975     


Gly Gln Val Ser Ala Ser Thr Ile Ser Ser Gly Val Pro Pro Glu Leu 
            980                 985                 990         


Pro Gly Pro Pro Thr Asn Leu Gly  Ile Ser Asn Ile Gly  Pro Arg Ser 
        995                 1000                 1005             


Val Thr  Leu Gln Phe Arg Pro  Gly Tyr Asp Gly Lys  Thr Ser Ile 
    1010                 1015                 1020             


Ser Arg  Trp Leu Val Glu Ala  Gln Val Gly Val Val  Gly Glu Gly 
    1025                 1030                 1035             


Glu Glu  Trp Leu Leu Ile His  Gln Leu Ser Asn Glu  Pro Asp Ala 
    1040                 1045                 1050             


Arg Ser  Met Glu Val Pro Asp  Leu Asn Pro Phe Thr  Cys Tyr Ser 
    1055                 1060                 1065             


Phe Arg  Met Arg Gln Val Asn  Ile Val Gly Thr Ser  Pro Pro Ser 
    1070                 1075                 1080             


Gln Pro  Ser Arg Lys Ile Gln  Thr Leu Gln Ala Pro  Pro Asp Met 
    1085                 1090                 1095             


Ala Pro  Ala Asn Val Ser Leu  Arg Thr Ala Ser Glu  Thr Ser Leu 
    1100                 1105                 1110             


Trp Leu  Arg Trp Met Pro Leu  Pro Glu Met Glu Tyr  Asn Gly Asn 
    1115                 1120                 1125             


Pro Glu  Ser Val Gly Tyr Lys  Ile Lys Tyr Ser Arg  Ser Asp Gly 
    1130                 1135                 1140             


His Gly  Lys Thr Leu Ser His  Val Val Gln Asp Arg  Val Glu Arg 
    1145                 1150                 1155             


Asp Tyr  Thr Ile Glu Asp Leu  Glu Glu Trp Thr Glu  Tyr Arg Val 
    1160                 1165                 1170             


Gln Val  Gln Ala Phe Asn Ala  Ile Gly Ser Gly Pro  Trp Ser Gln 
    1175                 1180                 1185             


Thr Val  Val Gly Arg Thr Arg  Glu Ser Val Pro Ser  Ser Gly Pro 
    1190                 1195                 1200             


Thr Asn  Val Ser Ala Leu Ala  Thr Thr Ser Ser Ser  Met Leu Val 
    1205                 1210                 1215             


Arg Trp  Ser Glu Val Pro Glu  Ala Asp Arg Asn Gly  Leu Val Leu 
    1220                 1225                 1230             


Gly Tyr  Lys Val Met Tyr Lys  Glu Lys Asp Ser Asp  Thr Gln Pro 
    1235                 1240                 1245             


Arg Phe  Trp Leu Val Glu Gly  Asn Ser Ser Arg Ser  Ala Gln Leu 
    1250                 1255                 1260             


Thr Gly  Leu Gly Lys Tyr Val  Leu Tyr Glu Val Gln  Val Leu Ala 
    1265                 1270                 1275             


Phe Thr  Arg Ile Gly Asp Gly  Ser Pro Ser His Pro  Pro Ile Leu 
    1280                 1285                 1290             


Glu Arg  Thr Leu Asp Asp Val  Pro Gly Pro Pro Met  Gly Ile Leu 
    1295                 1300                 1305             


Phe Pro  Glu Val Arg Thr Thr  Ser Val Arg Leu Ile  Trp Gln Pro 
    1310                 1315                 1320             


Pro Ala  Ala Pro Asn Gly Ile  Ile Leu Ala Tyr Gln  Ile Thr His 
    1325                 1330                 1335             


Arg Leu  Asn Thr Thr Thr Ala  Asn Thr Ala Thr Val  Glu Val Leu 
    1340                 1345                 1350             


Ala Pro  Ser Ala Arg Gln Tyr  Thr Ala Thr Gly Leu  Lys Pro Glu 
    1355                 1360                 1365             


Ser Val  Tyr Leu Phe Arg Ile  Thr Ala Gln Thr Arg  Lys Gly Trp 
    1370                 1375                 1380             


Gly Glu  Ala Ala Glu Ala Leu  Val Val Thr Thr Glu  Lys Arg Asp 
    1385                 1390                 1395             


Arg Pro  Gln Pro Pro Ser Arg  Pro Met Val Gln Gln  Glu Asp Val 
    1400                 1405                 1410             


Arg Ala  Arg Ser Val Leu Leu  Ser Trp Glu Pro Gly  Ser Asp Gly 
    1415                 1420                 1425             


Leu Ser  Pro Val Arg Tyr Tyr  Thr Ile Gln Thr Arg  Glu Leu Pro 
    1430                 1435                 1440             


Ser Gly  Arg Trp Ala Leu His  Ser Ala Ser Val Ser  His Asn Ala 
    1445                 1450                 1455             


Ser Ser  Phe Ile Val Asp Arg  Leu Lys Pro Phe Thr  Ser Tyr Lys 
    1460                 1465                 1470             


Phe Arg  Val Lys Ala Thr Asn  Asp Ile Gly Asp Ser  Glu Phe Ser 
    1475                 1480                 1485             


Glu Glu  Ser Glu Ser Leu Thr  Thr Leu Gln Ala Ala  Pro Asp Glu 
    1490                 1495                 1500             


Ala Pro  Thr Ile Leu Ser Val  Thr Pro His Thr Thr  Thr Ser Val 
    1505                 1510                 1515             


Leu Ile  Arg Trp Gln Pro Pro  Ala Glu Asp Lys Ile  Asn Gly Ile 
    1520                 1525                 1530             


Leu Leu  Gly Phe Arg Ile Arg  Tyr Arg Glu Leu Leu  Tyr Glu Gly 
    1535                 1540                 1545             


Leu Arg  Gly Phe Thr Leu Arg  Gly Ile Asn Asn Pro  Gly Ala Thr 
    1550                 1555                 1560             


Trp Ala  Glu Leu Thr Ser Met  Tyr Ser Met Arg Asn  Leu Ser Arg 
    1565                 1570                 1575             


Pro Ser  Leu Thr Gln Tyr Glu  Leu Asp Asn Leu Asn  Lys His Arg 
    1580                 1585                 1590             


Arg Tyr  Glu Ile Arg Met Ser  Val Tyr Asn Ala Val  Gly Glu Gly 
    1595                 1600                 1605             


Pro Ser  Ser Pro Pro Gln Glu  Val Phe Val Gly Glu  Ala Val Pro 
    1610                 1615                 1620             


Thr Ala  Ala Pro Arg Asn Val  Val Val His Gly Ala  Thr Ala Thr 
    1625                 1630                 1635             


Gln Leu  Asp Val Thr Trp Glu  Pro Pro Pro Leu Asp  Ser Gln Asn 
    1640                 1645                 1650             


Gly Asp  Ile Gln Gly Tyr Lys  Ile Tyr Phe Trp Glu  Ala Gln Arg 
    1655                 1660                 1665             


Gly Asn  Leu Thr Glu Arg Val  Lys Thr Leu Phe Leu  Ala Glu Asn 
    1670                 1675                 1680             


Ser Val  Lys Leu Lys Asn Leu  Thr Gly Tyr Thr Ala  Tyr Met Val 
    1685                 1690                 1695             


Ser Val  Ala Ala Phe Asn Ala  Ala Gly Asp Gly Pro  Arg Ser Thr 
    1700                 1705                 1710             


Pro Thr  Gln Gly Gln Thr Gln  Gln Ala Ala Pro Ser  Ala Pro Ser 
    1715                 1720                 1725             


Ser Val  Lys Phe Ser Glu Leu  Thr Thr Thr Ser Val  Asn Val Ser 
    1730                 1735                 1740             


Trp Glu  Ala Pro Gln Phe Pro  Asn Gly Ile Leu Glu  Gly Tyr Arg 
    1745                 1750                 1755             


Leu Val  Tyr Glu Pro Cys Ser  Pro Val Asp Gly Val  Ser Lys Ile 
    1760                 1765                 1770             


Val Thr  Val Asp Val Lys Gly  Asn Ser Pro Leu Trp  Leu Lys Val 
    1775                 1780                 1785             


Lys Asp  Leu Ala Glu Gly Val  Thr Tyr Arg Phe Arg  Ile Arg Ala 
    1790                 1795                 1800             


Lys Thr  Phe Thr Tyr Gly Pro  Glu Ile Glu Ala Asn  Val Thr Thr 
    1805                 1810                 1815             


Gly Pro  Gly Glu Gly Ala Pro  Gly Pro Pro Gly Val  Pro Ile Ile 
    1820                 1825                 1830             


Val Arg  Tyr Ser Ser Ala Ile  Ala Ile His Trp Ser  Ser Gly Asp 
    1835                 1840                 1845             


Pro Gly  Lys Gly Pro Ile Thr  Arg Tyr Val Ile Glu  Ala Arg Pro 
    1850                 1855                 1860             


Ser Asp  Glu Gly Leu Trp Asp  Ile Leu Ile Lys Asp  Ile Pro Lys 
    1865                 1870                 1875             


Glu Val  Ser Ser Tyr Thr Phe  Ser Met Asp Ile Leu  Lys Pro Gly 
    1880                 1885                 1890             


Val Ser  Tyr Asp Phe Arg Val  Ile Ala Val Asn Asp  Tyr Gly Phe 
    1895                 1900                 1905             


Gly Thr  Pro Ser Ser Pro Ser  Gln Ser Val Pro Ala  Gln Lys Ala 
    1910                 1915                 1920             


Asn Pro  Phe Tyr Glu Glu Trp  Trp Phe Leu Val Val  Ile Ala Leu 
    1925                 1930                 1935             


Val Gly  Leu Ile Phe Ile Leu  Leu Leu Val Phe Val  Leu Ile Ile 
    1940                 1945                 1950             


Arg Gly  Gln Ser Lys Lys Tyr  Ala Lys Lys Thr Asp  Ser Gly Asn 
    1955                 1960                 1965             


Ser Ala  Lys Ser Gly Ala Leu  Gly His Ser Glu Met  Met Ser Leu 
    1970                 1975                 1980             


Asp Glu  Ser Ser Phe Pro Ala  Leu Glu Leu Asn Asn  Arg Arg Leu 
    1985                 1990                 1995             


Ser Val  Lys Asn Ser Phe Cys  Arg Lys Asn Gly Leu  Tyr Thr Arg 
    2000                 2005                 2010             


Ser Pro  Pro Arg Pro Ser Pro  Gly Ser Leu His Tyr  Ser Asp Glu 
    2015                 2020                 2025             


Asp Val  Thr Lys Tyr Asn Asp  Leu Ile Pro Ala Glu  Ser Ser Ser 
    2030                 2035                 2040             


Leu Thr  Glu Lys Pro Ser Glu  Ile Ser Asp Ser Gln  Gly Ser Asp 
    2045                 2050                 2055             


Ser Glu  Tyr Glu Val Asp Ser  Asn His Gln Lys Ala  His Ser Phe 
    2060                 2065                 2070             


Val Asn  His Tyr Ile Ser Asp  Pro Thr Tyr Tyr Asn  Ser Trp Arg 
    2075                 2080                 2085             


Arg Gln  Gln Lys Gly Ile Ser  Arg Ala Gln Ala Tyr  Ser Tyr Thr 
    2090                 2095                 2100             


Glu Ser  Asp Ser Gly Glu Pro  Asp His Thr Thr Val  Thr Asn Ser 
    2105                 2110                 2115             


Thr Ser  Thr Gln Gln Gly Ser  Leu Phe Arg Pro Lys  Ala Ser Arg 
    2120                 2125                 2130             


Thr Pro  Thr Pro Gln Asn Pro  Pro Asn Pro Pro Ser  Gln Gln Ser 
    2135                 2140                 2145             


Thr Leu  Tyr Arg Pro Pro Ser  Ser Leu Ala Pro Gly  Ser Arg Ala 
    2150                 2155                 2160             


Pro Ile  Ala Gly Phe Ser Ser  Phe Val 
    2165                 2170         


<210>  3250
<211>  480
<212>  PRT
<213>  homo sapiens

<400>  3250

Met Glu Arg Asp Glu Pro Pro Pro Ser Gly Gly Gly Gly Gly Gly Gly 
1               5                   10                  15      


Ser Ala Gly Phe Leu Glu Pro Pro Ala Ala Leu Pro Pro Pro Pro Arg 
            20                  25                  30          


Asn Gly Phe Cys Gln Asp Glu Leu Ala Glu Leu Asp Pro Gly Thr Ile 
        35                  40                  45              


Ser Val Ser Asp Asp Arg Ala Glu Gln Arg Thr Cys Leu Ile Cys Gly 
    50                  55                  60                  


Asp Arg Ala Thr Gly Leu His Tyr Gly Ile Ile Ser Cys Glu Gly Cys 
65                  70                  75                  80  


Lys Gly Phe Phe Lys Arg Ser Ile Cys Asn Lys Arg Val Tyr Arg Cys 
                85                  90                  95      


Ser Arg Asp Lys Asn Cys Val Met Ser Arg Lys Gln Arg Asn Arg Cys 
            100                 105                 110         


Gln Tyr Cys Arg Leu Leu Lys Cys Leu Gln Met Gly Met Asn Arg Lys 
        115                 120                 125             


Ala Ile Arg Glu Asp Gly Met Pro Gly Gly Arg Asn Lys Ser Ile Gly 
    130                 135                 140                 


Pro Val Gln Ile Ser Glu Glu Glu Ile Glu Arg Ile Met Ser Gly Gln 
145                 150                 155                 160 


Glu Phe Glu Glu Glu Ala Asn His Trp Ser Asn His Gly Asp Ser Asp 
                165                 170                 175     


His Ser Ser Pro Gly Asn Arg Ala Ser Glu Ser Asn Gln Pro Ser Pro 
            180                 185                 190         


Gly Ser Thr Leu Ser Ser Ser Arg Ser Val Glu Leu Asn Gly Phe Met 
        195                 200                 205             


Ala Phe Arg Glu Gln Tyr Met Gly Met Ser Val Pro Pro His Tyr Gln 
    210                 215                 220                 


Tyr Ile Pro His Leu Phe Ser Tyr Ser Gly His Ser Pro Leu Leu Pro 
225                 230                 235                 240 


Gln Gln Ala Arg Ser Leu Asp Pro Gln Ser Tyr Ser Leu Ile His Gln 
                245                 250                 255     


Leu Leu Ser Ala Glu Asp Leu Glu Pro Leu Gly Thr Pro Met Leu Ile 
            260                 265                 270         


Glu Asp Gly Tyr Ala Val Thr Gln Ala Glu Leu Phe Ala Leu Leu Cys 
        275                 280                 285             


Arg Leu Ala Asp Glu Leu Leu Phe Arg Gln Ile Ala Trp Ile Lys Lys 
    290                 295                 300                 


Leu Pro Phe Phe Cys Glu Leu Ser Ile Lys Asp Tyr Thr Cys Leu Leu 
305                 310                 315                 320 


Ser Ser Thr Trp Gln Glu Leu Ile Leu Leu Ser Ser Leu Thr Val Tyr 
                325                 330                 335     


Ser Lys Gln Ile Phe Gly Glu Leu Ala Asp Val Thr Ala Lys Tyr Ser 
            340                 345                 350         


Pro Ser Asp Glu Glu Leu His Arg Phe Ser Asp Glu Gly Met Glu Val 
        355                 360                 365             


Ile Glu Arg Leu Ile Tyr Leu Tyr His Lys Phe His Gln Leu Lys Val 
    370                 375                 380                 


Ser Asn Glu Glu Tyr Ala Cys Met Lys Ala Ile Asn Phe Leu Asn Gln 
385                 390                 395                 400 


Asp Ile Arg Gly Leu Thr Ser Ala Ser Gln Leu Glu Gln Leu Asn Lys 
                405                 410                 415     


Arg Tyr Trp Tyr Ile Cys Gln Asp Phe Thr Glu Tyr Lys Tyr Thr His 
            420                 425                 430         


Gln Pro Asn Arg Phe Pro Asp Leu Met Met Cys Leu Pro Glu Ile Arg 
        435                 440                 445             


Tyr Ile Ala Gly Lys Met Val Asn Val Pro Leu Glu Gln Leu Pro Leu 
    450                 455                 460                 


Leu Phe Lys Val Val Leu His Ser Cys Lys Thr Ser Val Gly Lys Glu 
465                 470                 475                 480 


<210>  3251
<211>  200
<212>  PRT
<213>  homo sapiens

<400>  3251

Met Ala Lys Lys Thr Tyr Asp Leu Leu Phe Lys Leu Leu Leu Ile Gly 
1               5                   10                  15      


Asp Ser Gly Val Gly Lys Thr Cys Val Leu Phe Arg Phe Ser Asp Asp 
            20                  25                  30          


Ala Phe Asn Thr Thr Phe Ile Ser Thr Ile Gly Ile Asp Phe Lys Ile 
        35                  40                  45              


Lys Thr Val Glu Leu Gln Gly Lys Lys Ile Lys Leu Gln Ile Trp Asp 
    50                  55                  60                  


Thr Ala Gly Gln Glu Arg Phe His Thr Ile Thr Thr Ser Tyr Tyr Arg 
65                  70                  75                  80  


Gly Ala Met Gly Ile Met Leu Val Tyr Asp Ile Thr Asn Gly Lys Ser 
                85                  90                  95      


Phe Glu Asn Ile Ser Lys Trp Leu Arg Asn Ile Asp Glu His Ala Asn 
            100                 105                 110         


Glu Asp Val Glu Arg Met Leu Leu Gly Asn Lys Cys Asp Met Asp Asp 
        115                 120                 125             


Lys Arg Val Val Pro Lys Gly Lys Gly Glu Gln Ile Ala Arg Glu His 
    130                 135                 140                 


Gly Ile Arg Phe Phe Glu Thr Ser Ala Lys Ala Asn Ile Asn Ile Glu 
145                 150                 155                 160 


Lys Ala Phe Leu Thr Leu Ala Glu Asp Ile Leu Arg Lys Thr Pro Val 
                165                 170                 175     


Lys Glu Pro Asn Ser Glu Asn Val Asp Ile Ser Ser Gly Gly Gly Val 
            180                 185                 190         


Thr Gly Trp Lys Ser Lys Cys Cys 
        195                 200 


<210>  3252
<211>  203
<212>  PRT
<213>  homo sapiens

<400>  3252

Met Ala Lys Ala Tyr Asp His Leu Phe Lys Leu Leu Leu Ile Gly Asp 
1               5                   10                  15      


Ser Gly Val Gly Lys Thr Cys Leu Ile Ile Arg Phe Ala Glu Asp Asn 
            20                  25                  30          


Phe Asn Asn Thr Tyr Ile Ser Thr Ile Gly Ile Asp Phe Lys Ile Arg 
        35                  40                  45              


Thr Val Asp Ile Glu Gly Lys Lys Ile Lys Leu Gln Val Trp Asp Thr 
    50                  55                  60                  


Ala Gly Gln Glu Arg Phe Lys Thr Ile Thr Thr Ala Tyr Tyr Arg Gly 
65                  70                  75                  80  


Ala Met Gly Ile Ile Leu Val Tyr Asp Ile Thr Asp Glu Lys Ser Phe 
                85                  90                  95      


Glu Asn Ile Gln Asn Trp Met Lys Ser Ile Lys Glu Asn Ala Ser Ala 
            100                 105                 110         


Gly Val Glu Arg Leu Leu Leu Gly Asn Lys Cys Asp Met Glu Ala Lys 
        115                 120                 125             


Arg Lys Val Gln Lys Glu Gln Ala Asp Lys Leu Ala Arg Glu His Gly 
    130                 135                 140                 


Ile Arg Phe Phe Glu Thr Ser Ala Lys Ser Ser Met Asn Val Asp Glu 
145                 150                 155                 160 


Ala Phe Ser Ser Leu Ala Arg Asp Ile Leu Leu Lys Ser Gly Gly Arg 
                165                 170                 175     


Arg Ser Gly Asn Gly Asn Lys Pro Pro Ser Thr Asp Leu Lys Thr Cys 
            180                 185                 190         


Asp Lys Lys Asn Thr Asn Lys Cys Ser Leu Gly 
        195                 200             


<210>  3253
<211>  195
<212>  PRT
<213>  homo sapiens

<400>  3253

Met Glu Asn His Lys Ser Asn Asn Lys Glu Asn Ile Thr Ile Val Asp 
1               5                   10                  15      


Ile Ser Arg Lys Ile Asn Gln Leu Pro Glu Ala Glu Arg Asn Leu Leu 
            20                  25                  30          


Glu Asn Gly Ser Val Tyr Val Gly Leu Asn Ala Ala Leu Cys Gly Leu 
        35                  40                  45              


Ile Ala Asn Ser Leu Phe Arg Arg Ile Leu Asn Val Thr Lys Ala Arg 
    50                  55                  60                  


Ile Ala Ala Gly Leu Pro Met Ala Gly Ile Pro Phe Leu Thr Thr Asp 
65                  70                  75                  80  


Leu Thr Tyr Arg Cys Phe Val Ser Phe Pro Leu Asn Thr Gly Asp Leu 
                85                  90                  95      


Asp Cys Glu Thr Cys Thr Ile Thr Arg Ser Gly Leu Thr Gly Leu Val 
            100                 105                 110         


Ile Gly Gly Leu Tyr Pro Val Phe Leu Ala Ile Pro Val Asn Gly Gly 
        115                 120                 125             


Leu Ala Ala Arg Tyr Gln Ser Ala Leu Leu Pro His Lys Gly Asn Ile 
    130                 135                 140                 


Leu Ser Tyr Trp Ile Arg Thr Ser Lys Pro Val Phe Arg Lys Met Leu 
145                 150                 155                 160 


Phe Pro Ile Leu Leu Gln Thr Met Phe Ser Ala Tyr Leu Gly Ser Glu 
                165                 170                 175     


Gln Tyr Lys Leu Leu Ile Lys Ala Leu Gln Leu Ser Glu Pro Gly Lys 
            180                 185                 190         


Glu Ile His 
        195 


<210>  3254
<211>  201
<212>  PRT
<213>  homo sapiens

<400>  3254

Met Ala Met His Asn Lys Ala Ala Pro Pro Gln Ile Pro Asp Thr Arg 
1               5                   10                  15      


Arg Glu Leu Ala Glu Leu Val Lys Arg Lys Gln Glu Leu Ala Glu Thr 
            20                  25                  30          


Leu Ala Asn Leu Glu Arg Gln Ile Tyr Ala Phe Glu Gly Ser Tyr Leu 
        35                  40                  45              


Glu Asp Thr Gln Met Tyr Gly Asn Ile Ile Arg Gly Trp Asp Arg Tyr 
    50                  55                  60                  


Leu Thr Asn Gln Lys Asn Ser Asn Ser Lys Asn Asp Arg Arg Asn Arg 
65                  70                  75                  80  


Lys Phe Lys Glu Ala Glu Arg Leu Phe Ser Lys Ser Ser Val Thr Ser 
                85                  90                  95      


Ala Ala Ala Val Ser Ala Leu Ala Gly Val Gln Asp Gln Leu Ile Glu 
            100                 105                 110         


Lys Arg Glu Pro Gly Ser Gly Thr Glu Ser Asp Thr Ser Pro Asp Phe 
        115                 120                 125             


His Asn Gln Glu Asn Glu Pro Ser Gln Glu Asp Pro Glu Asp Leu Asp 
    130                 135                 140                 


Gly Ser Val Gln Gly Val Lys Pro Gln Lys Ala Ala Ser Ser Thr Ser 
145                 150                 155                 160 


Ser Gly Ser His His Ser Ser His Lys Lys Arg Lys Asn Lys Asn Arg 
                165                 170                 175     


His Ser Pro Ser Gly Met Phe Asp Tyr Asp Phe Glu Ile Asp Leu Lys 
            180                 185                 190         


Leu Asn Lys Lys Pro Arg Ala Asp Tyr 
        195                 200     


<210>  3255
<211>  910
<212>  PRT
<213>  homo sapiens

<400>  3255

Met Lys Lys Met Ser Arg Asn Val Leu Leu Gln Met Glu Glu Glu Glu 
1               5                   10                  15      


Asp Asp Asp Asp Gly Asp Ile Val Leu Glu Asn Leu Gly Gln Thr Ile 
            20                  25                  30          


Val Pro Asp Leu Gly Ser Leu Glu Ser Gln His Asp Phe Arg Thr Pro 
        35                  40                  45              


Glu Phe Glu Glu Phe Asn Gly Lys Pro Asp Ser Leu Phe Phe Asn Asp 
    50                  55                  60                  


Gly Gln Arg Arg Ile Asp Phe Val Leu Val Tyr Glu Asp Glu Ser Arg 
65                  70                  75                  80  


Lys Glu Thr Asn Lys Lys Gly Thr Asn Glu Lys Gln Arg Arg Lys Arg 
                85                  90                  95      


Gln Ala Tyr Glu Ser Asn Leu Ile Cys His Gly Leu Gln Leu Glu Ala 
            100                 105                 110         


Thr Arg Ser Val Leu Asp Asp Lys Leu Val Phe Val Lys Val His Ala 
        115                 120                 125             


Pro Trp Glu Val Leu Cys Thr Tyr Ala Glu Ile Met His Ile Lys Leu 
    130                 135                 140                 


Pro Leu Lys Pro Asn Asp Leu Lys Asn Arg Ser Ser Ala Phe Gly Thr 
145                 150                 155                 160 


Leu Asn Trp Phe Thr Lys Val Leu Ser Val Asp Glu Ser Ile Ile Lys 
                165                 170                 175     


Pro Glu Gln Glu Phe Phe Thr Ala Pro Phe Glu Lys Asn Arg Met Asn 
            180                 185                 190         


Asp Phe Tyr Ile Val Asp Arg Asp Ala Phe Phe Asn Pro Ala Thr Arg 
        195                 200                 205             


Ser Arg Ile Val Tyr Phe Ile Leu Ser Arg Val Lys Tyr Gln Val Ile 
    210                 215                 220                 


Asn Asn Val Ser Lys Phe Gly Ile Asn Arg Leu Val Asn Ser Gly Ile 
225                 230                 235                 240 


Tyr Lys Ala Ala Phe Pro Leu His Asp Cys Lys Phe Arg Arg Gln Ser 
                245                 250                 255     


Glu Asp Pro Ser Cys Pro Asn Glu Arg Tyr Leu Leu Tyr Arg Glu Trp 
            260                 265                 270         


Ala His Pro Arg Ser Ile Tyr Lys Lys Gln Pro Leu Asp Leu Ile Arg 
        275                 280                 285             


Lys Tyr Tyr Gly Glu Lys Ile Gly Ile Tyr Phe Ala Trp Leu Gly Tyr 
    290                 295                 300                 


Tyr Thr Gln Met Leu Leu Leu Ala Ala Val Val Gly Val Ala Cys Phe 
305                 310                 315                 320 


Leu Tyr Gly Tyr Leu Asn Gln Asp Asn Cys Thr Trp Ser Lys Glu Val 
                325                 330                 335     


Cys His Pro Asp Ile Gly Gly Lys Ile Ile Met Cys Pro Gln Cys Asp 
            340                 345                 350         


Arg Leu Cys Pro Phe Trp Lys Leu Asn Ile Thr Cys Glu Ser Ser Lys 
        355                 360                 365             


Lys Leu Cys Ile Phe Asp Ser Phe Gly Thr Leu Val Phe Ala Val Phe 
    370                 375                 380                 


Met Gly Val Trp Val Thr Leu Phe Leu Glu Phe Trp Lys Arg Arg Gln 
385                 390                 395                 400 


Ala Glu Leu Glu Tyr Glu Trp Asp Thr Val Glu Leu Gln Gln Glu Glu 
                405                 410                 415     


Gln Ala Arg Pro Glu Tyr Glu Ala Arg Cys Thr His Val Val Ile Asn 
            420                 425                 430         


Glu Ile Thr Gln Glu Glu Glu Arg Ile Pro Phe Thr Ala Trp Gly Lys 
        435                 440                 445             


Cys Ile Arg Ile Thr Leu Cys Ala Ser Ala Val Phe Phe Trp Ile Leu 
    450                 455                 460                 


Leu Ile Ile Ala Ser Val Ile Gly Ile Ile Val Tyr Arg Leu Ser Val 
465                 470                 475                 480 


Phe Ile Val Phe Ser Ala Lys Leu Pro Lys Asn Ile Asn Gly Thr Asp 
                485                 490                 495     


Pro Ile Gln Lys Tyr Leu Thr Pro Gln Thr Ala Thr Ser Ile Thr Ala 
            500                 505                 510         


Ser Ile Ile Ser Phe Ile Ile Ile Met Ile Leu Asn Thr Ile Tyr Glu 
        515                 520                 525             


Lys Val Ala Ile Met Ile Thr Asn Phe Glu Leu Pro Arg Thr Gln Thr 
    530                 535                 540                 


Asp Tyr Glu Asn Ser Leu Thr Met Lys Met Phe Leu Phe Gln Phe Val 
545                 550                 555                 560 


Asn Tyr Tyr Ser Ser Cys Phe Tyr Ile Ala Phe Phe Lys Gly Lys Phe 
                565                 570                 575     


Val Gly Tyr Pro Gly Asp Pro Val Tyr Trp Leu Gly Lys Tyr Arg Asn 
            580                 585                 590         


Glu Glu Cys Asp Pro Gly Gly Cys Leu Leu Glu Leu Thr Thr Gln Leu 
        595                 600                 605             


Thr Ile Ile Met Gly Gly Lys Ala Ile Trp Asn Asn Ile Gln Glu Val 
    610                 615                 620                 


Leu Leu Pro Trp Ile Met Asn Leu Ile Gly Arg Phe His Arg Val Ser 
625                 630                 635                 640 


Gly Ser Glu Lys Ile Thr Pro Arg Trp Glu Gln Asp Tyr His Leu Gln 
                645                 650                 655     


Pro Met Gly Lys Leu Gly Leu Phe Tyr Glu Tyr Leu Glu Met Ile Ile 
            660                 665                 670         


Gln Phe Gly Phe Val Thr Leu Phe Val Ala Ser Phe Pro Leu Ala Pro 
        675                 680                 685             


Leu Leu Ala Leu Val Asn Asn Ile Leu Glu Ile Arg Val Asp Ala Trp 
    690                 695                 700                 


Lys Leu Thr Thr Gln Phe Arg Arg Leu Val Pro Glu Lys Ala Gln Asp 
705                 710                 715                 720 


Ile Gly Ala Trp Gln Pro Ile Met Gln Gly Ile Ala Ile Leu Ala Val 
                725                 730                 735     


Val Thr Asn Ala Met Ile Ile Ala Phe Thr Ser Asp Met Ile Pro Arg 
            740                 745                 750         


Leu Val Tyr Tyr Trp Ser Phe Ser Val Pro Pro Tyr Gly Asp His Thr 
        755                 760                 765             


Ser Tyr Thr Met Glu Gly Tyr Ile Asn Asn Thr Leu Ser Ile Phe Lys 
    770                 775                 780                 


Val Ala Asp Phe Lys Asn Lys Ser Lys Gly Asn Pro Tyr Ser Asp Leu 
785                 790                 795                 800 


Gly Asn His Thr Thr Cys Arg Tyr Arg Asp Phe Arg Tyr Pro Pro Gly 
                805                 810                 815     


His Pro Gln Glu Tyr Lys His Asn Ile Tyr Tyr Trp His Val Ile Ala 
            820                 825                 830         


Ala Lys Leu Ala Phe Ile Ile Val Met Glu His Val Ile Tyr Ser Val 
        835                 840                 845             


Lys Phe Phe Ile Ser Tyr Ala Ile Pro Asp Val Ser Lys Arg Thr Lys 
    850                 855                 860                 


Ser Lys Ile Gln Arg Glu Lys Tyr Leu Thr Gln Lys Leu Leu His Glu 
865                 870                 875                 880 


Asn His Leu Lys Asp Met Thr Lys Asn Met Gly Val Ile Ala Glu Arg 
                885                 890                 895     


Met Ile Glu Ala Val Asp Asn Asn Leu Arg Pro Lys Ser Glu 
            900                 905                 910 


<210>  3256
<211>  1786
<212>  PRT
<213>  homo sapiens

<400>  3256

Met Gly Leu Leu Gln Leu Leu Ala Phe Ser Phe Leu Ala Leu Cys Arg 
1               5                   10                  15      


Ala Arg Val Arg Ala Gln Glu Pro Glu Phe Ser Tyr Gly Cys Ala Glu 
            20                  25                  30          


Gly Ser Cys Tyr Pro Ala Thr Gly Asp Leu Leu Ile Gly Arg Ala Gln 
        35                  40                  45              


Lys Leu Ser Val Thr Ser Thr Cys Gly Leu His Lys Pro Glu Pro Tyr 
    50                  55                  60                  


Cys Ile Val Ser His Leu Gln Glu Asp Lys Lys Cys Phe Ile Cys Asn 
65                  70                  75                  80  


Ser Gln Asp Pro Tyr His Glu Thr Leu Asn Pro Asp Ser His Leu Ile 
                85                  90                  95      


Glu Asn Val Val Thr Thr Phe Ala Pro Asn Arg Leu Lys Ile Trp Trp 
            100                 105                 110         


Gln Ser Glu Asn Gly Val Glu Asn Val Thr Ile Gln Leu Asp Leu Glu 
        115                 120                 125             


Ala Glu Phe His Phe Thr His Leu Ile Met Thr Phe Lys Thr Phe Arg 
    130                 135                 140                 


Pro Ala Ala Met Leu Ile Glu Arg Ser Ser Asp Phe Gly Lys Thr Trp 
145                 150                 155                 160 


Gly Val Tyr Arg Tyr Phe Ala Tyr Asp Cys Glu Ala Ser Phe Pro Gly 
                165                 170                 175     


Ile Ser Thr Gly Pro Met Lys Lys Val Asp Asp Ile Ile Cys Asp Ser 
            180                 185                 190         


Arg Tyr Ser Asp Ile Glu Pro Ser Thr Glu Gly Glu Val Ile Phe Arg 
        195                 200                 205             


Ala Leu Asp Pro Ala Phe Lys Ile Glu Asp Pro Tyr Ser Pro Arg Ile 
    210                 215                 220                 


Gln Asn Leu Leu Lys Ile Thr Asn Leu Arg Ile Lys Phe Val Lys Leu 
225                 230                 235                 240 


His Thr Leu Gly Asp Asn Leu Leu Asp Ser Arg Met Glu Ile Arg Glu 
                245                 250                 255     


Lys Tyr Tyr Tyr Ala Val Tyr Asp Met Val Val Arg Gly Asn Cys Phe 
            260                 265                 270         


Cys Tyr Gly His Ala Ser Glu Cys Ala Pro Val Asp Gly Phe Asn Glu 
        275                 280                 285             


Glu Val Glu Gly Met Val His Gly His Cys Met Cys Arg His Asn Thr 
    290                 295                 300                 


Lys Gly Leu Asn Cys Glu Leu Cys Met Asp Phe Tyr His Asp Leu Pro 
305                 310                 315                 320 


Trp Arg Pro Ala Glu Gly Arg Asn Ser Asn Ala Cys Lys Lys Cys Asn 
                325                 330                 335     


Cys Asn Glu His Ser Ile Ser Cys His Phe Asp Met Ala Val Tyr Leu 
            340                 345                 350         


Ala Thr Gly Asn Val Ser Gly Gly Val Cys Asp Asp Cys Gln His Asn 
        355                 360                 365             


Thr Met Gly Arg Asn Cys Glu Gln Cys Lys Pro Phe Tyr Tyr Gln His 
    370                 375                 380                 


Pro Glu Arg Asp Ile Arg Asp Pro Asn Phe Cys Glu Arg Cys Thr Cys 
385                 390                 395                 400 


Asp Pro Ala Gly Ser Gln Asn Glu Gly Ile Cys Asp Ser Tyr Thr Asp 
                405                 410                 415     


Phe Ser Thr Gly Leu Ile Ala Gly Gln Cys Arg Cys Lys Leu Asn Val 
            420                 425                 430         


Glu Gly Glu His Cys Asp Val Cys Lys Glu Gly Phe Tyr Asp Leu Ser 
        435                 440                 445             


Ser Glu Asp Pro Phe Gly Cys Lys Ser Cys Ala Cys Asn Pro Leu Gly 
    450                 455                 460                 


Thr Ile Pro Gly Gly Asn Pro Cys Asp Ser Glu Thr Gly His Cys Tyr 
465                 470                 475                 480 


Cys Lys Arg Leu Val Thr Gly Gln His Cys Asp Gln Cys Leu Pro Glu 
                485                 490                 495     


His Trp Gly Leu Ser Asn Asp Leu Asp Gly Cys Arg Pro Cys Asp Cys 
            500                 505                 510         


Asp Leu Gly Gly Ala Leu Asn Asn Ser Cys Phe Ala Glu Ser Gly Gln 
        515                 520                 525             


Cys Ser Cys Arg Pro His Met Ile Gly Arg Gln Cys Asn Glu Val Glu 
    530                 535                 540                 


Pro Gly Tyr Tyr Phe Ala Thr Leu Asp His Tyr Leu Tyr Glu Ala Glu 
545                 550                 555                 560 


Glu Ala Asn Leu Gly Pro Gly Val Ser Ile Val Glu Arg Gln Tyr Ile 
                565                 570                 575     


Gln Asp Arg Ile Pro Ser Trp Thr Gly Ala Gly Phe Val Arg Val Pro 
            580                 585                 590         


Glu Gly Ala Tyr Leu Glu Phe Phe Ile Asp Asn Ile Pro Tyr Ser Met 
        595                 600                 605             


Glu Tyr Asp Ile Leu Ile Arg Tyr Glu Pro Gln Leu Pro Asp His Trp 
    610                 615                 620                 


Glu Lys Ala Val Ile Thr Val Gln Arg Pro Gly Arg Ile Pro Thr Ser 
625                 630                 635                 640 


Ser Arg Cys Gly Asn Thr Ile Pro Asp Asp Asp Asn Gln Val Val Ser 
                645                 650                 655     


Leu Ser Pro Gly Ser Arg Tyr Val Val Leu Pro Arg Pro Val Cys Phe 
            660                 665                 670         


Glu Lys Gly Thr Asn Tyr Thr Val Arg Leu Glu Leu Pro Gln Tyr Thr 
        675                 680                 685             


Ser Ser Asp Ser Asp Val Glu Ser Pro Tyr Thr Leu Ile Asp Ser Leu 
    690                 695                 700                 


Val Leu Met Pro Tyr Cys Lys Ser Leu Asp Ile Phe Thr Val Gly Gly 
705                 710                 715                 720 


Ser Gly Asp Gly Val Val Thr Asn Ser Ala Trp Glu Thr Phe Gln Arg 
                725                 730                 735     


Tyr Arg Cys Leu Glu Asn Ser Arg Ser Val Val Lys Thr Pro Met Thr 
            740                 745                 750         


Asp Val Cys Arg Asn Ile Ile Phe Ser Ile Ser Ala Leu Leu His Gln 
        755                 760                 765             


Thr Gly Leu Ala Cys Glu Cys Asp Pro Gln Gly Ser Leu Ser Ser Val 
    770                 775                 780                 


Cys Asp Pro Asn Gly Gly Gln Cys Gln Cys Arg Pro Asn Val Val Gly 
785                 790                 795                 800 


Arg Thr Cys Asn Arg Cys Ala Pro Gly Thr Phe Gly Phe Gly Pro Ser 
                805                 810                 815     


Gly Cys Lys Pro Cys Glu Cys His Leu Gln Gly Ser Val Asn Ala Phe 
            820                 825                 830         


Cys Asn Pro Val Thr Gly Gln Cys His Cys Phe Gln Gly Val Tyr Ala 
        835                 840                 845             


Arg Gln Cys Asp Arg Cys Leu Pro Gly His Trp Gly Phe Pro Ser Cys 
    850                 855                 860                 


Gln Pro Cys Gln Cys Asn Gly His Ala Asp Asp Cys Asp Pro Val Thr 
865                 870                 875                 880 


Gly Glu Cys Leu Asn Cys Gln Asp Tyr Thr Met Gly His Asn Cys Glu 
                885                 890                 895     


Arg Cys Leu Ala Gly Tyr Tyr Gly Asp Pro Ile Ile Gly Ser Gly Asp 
            900                 905                 910         


His Cys Arg Pro Cys Pro Cys Pro Asp Gly Pro Asp Ser Gly Arg Gln 
        915                 920                 925             


Phe Ala Arg Ser Cys Tyr Gln Asp Pro Val Thr Leu Gln Leu Ala Cys 
    930                 935                 940                 


Val Cys Asp Pro Gly Tyr Ile Gly Ser Arg Cys Asp Asp Cys Ala Ser 
945                 950                 955                 960 


Gly Tyr Phe Gly Asn Pro Ser Glu Val Gly Gly Ser Cys Gln Pro Cys 
                965                 970                 975     


Gln Cys His Asn Asn Ile Asp Thr Thr Asp Pro Glu Ala Cys Asp Lys 
            980                 985                 990         


Glu Thr Gly Arg Cys Leu Lys Cys  Leu Tyr His Thr Glu  Gly Glu His 
        995                 1000                 1005             


Cys Gln  Phe Cys Arg Phe Gly  Tyr Tyr Gly Asp Ala  Leu Gln Gln 
    1010                 1015                 1020             


Asp Cys  Arg Lys Cys Val Cys  Asn Tyr Leu Gly Thr  Val Gln Glu 
    1025                 1030                 1035             


His Cys  Asn Gly Ser Asp Cys  Gln Cys Asp Lys Ala  Thr Gly Gln 
    1040                 1045                 1050             


Cys Leu  Cys Leu Pro Asn Val  Ile Gly Gln Asn Cys  Asp Arg Cys 
    1055                 1060                 1065             


Ala Pro  Asn Thr Trp Gln Leu  Ala Ser Gly Thr Gly  Cys Asp Pro 
    1070                 1075                 1080             


Cys Asn  Cys Asn Ala Ala His  Ser Phe Gly Pro Ser  Cys Asn Glu 
    1085                 1090                 1095             


Phe Thr  Gly Gln Cys Gln Cys  Met Pro Gly Phe Gly  Gly Arg Thr 
    1100                 1105                 1110             


Cys Ser  Glu Cys Gln Glu Leu  Phe Trp Gly Asp Pro  Asp Val Glu 
    1115                 1120                 1125             


Cys Arg  Ala Cys Asp Cys Asp  Pro Arg Gly Ile Glu  Thr Pro Gln 
    1130                 1135                 1140             


Cys Asp  Gln Ser Thr Gly Gln  Cys Val Cys Val Glu  Gly Val Glu 
    1145                 1150                 1155             


Gly Pro  Arg Cys Asp Lys Cys  Thr Arg Gly Tyr Ser  Gly Val Phe 
    1160                 1165                 1170             


Pro Asp  Cys Thr Pro Cys His  Gln Cys Phe Ala Leu  Trp Asp Val 
    1175                 1180                 1185             


Ile Ile  Ala Glu Leu Thr Asn  Arg Thr His Arg Phe  Leu Glu Lys 
    1190                 1195                 1200             


Ala Lys  Ala Leu Lys Ile Ser  Gly Val Ile Gly Pro  Tyr Arg Glu 
    1205                 1210                 1215             


Thr Val  Asp Ser Val Glu Arg  Lys Val Ser Glu Ile  Lys Asp Ile 
    1220                 1225                 1230             


Leu Ala  Gln Ser Pro Ala Ala  Glu Pro Leu Lys Asn  Ile Gly Asn 
    1235                 1240                 1245             


Leu Phe  Glu Glu Ala Glu Lys  Leu Ile Lys Asp Val  Thr Glu Met 
    1250                 1255                 1260             


Met Ala  Gln Val Glu Val Lys  Leu Ser Asp Thr Thr  Ser Gln Ser 
    1265                 1270                 1275             


Asn Ser  Thr Ala Lys Glu Leu  Asp Ser Leu Gln Thr  Glu Ala Glu 
    1280                 1285                 1290             


Ser Leu  Asp Asn Thr Val Lys  Glu Leu Ala Glu Gln  Leu Glu Phe 
    1295                 1300                 1305             


Ile Lys  Asn Ser Asp Ile Arg  Gly Ala Leu Asp Ser  Ile Thr Lys 
    1310                 1315                 1320             


Tyr Phe  Gln Met Ser Leu Glu  Ala Glu Glu Arg Val  Asn Ala Ser 
    1325                 1330                 1335             


Thr Thr  Glu Pro Asn Ser Thr  Val Glu Gln Ser Ala  Leu Met Arg 
    1340                 1345                 1350             


Asp Arg  Val Glu Asp Val Met  Met Glu Arg Glu Ser  Gln Phe Lys 
    1355                 1360                 1365             


Glu Lys  Gln Glu Glu Gln Ala  Arg Leu Leu Asp Glu  Leu Ala Gly 
    1370                 1375                 1380             


Lys Leu  Gln Ser Leu Asp Leu  Ser Ala Ala Ala Glu  Met Thr Cys 
    1385                 1390                 1395             


Gly Thr  Pro Pro Gly Ala Ser  Cys Ser Glu Thr Glu  Cys Gly Gly 
    1400                 1405                 1410             


Pro Asn  Cys Arg Thr Asp Glu  Gly Glu Arg Lys Cys  Gly Gly Pro 
    1415                 1420                 1425             


Gly Cys  Gly Gly Leu Val Thr  Val Ala His Asn Ala  Trp Gln Lys 
    1430                 1435                 1440             


Ala Met  Asp Leu Asp Gln Asp  Val Leu Ser Ala Leu  Ala Glu Val 
    1445                 1450                 1455             


Glu Gln  Leu Ser Lys Met Val  Ser Glu Ala Lys Leu  Arg Ala Asp 
    1460                 1465                 1470             


Glu Ala  Lys Gln Ser Ala Glu  Asp Ile Leu Leu Lys  Thr Asn Ala 
    1475                 1480                 1485             


Thr Lys  Glu Lys Met Asp Lys  Ser Asn Glu Glu Leu  Arg Asn Leu 
    1490                 1495                 1500             


Ile Lys  Gln Ile Arg Asn Phe  Leu Thr Gln Asp Ser  Ala Asp Leu 
    1505                 1510                 1515             


Asp Ser  Ile Glu Ala Val Ala  Asn Glu Val Leu Lys  Met Glu Met 
    1520                 1525                 1530             


Pro Ser  Thr Pro Gln Gln Leu  Gln Asn Leu Thr Glu  Asp Ile Arg 
    1535                 1540                 1545             


Glu Arg  Val Glu Ser Leu Ser  Gln Val Glu Val Ile  Leu Gln His 
    1550                 1555                 1560             


Ser Ala  Ala Asp Ile Ala Arg  Ala Glu Met Leu Leu  Glu Glu Ala 
    1565                 1570                 1575             


Lys Arg  Ala Ser Lys Ser Ala  Thr Asp Val Lys Val  Thr Ala Asp 
    1580                 1585                 1590             


Met Val  Lys Glu Ala Leu Glu  Glu Ala Glu Lys Ala  Gln Val Ala 
    1595                 1600                 1605             


Ala Glu  Lys Ala Ile Lys Gln  Ala Asp Glu Asp Ile  Gln Gly Thr 
    1610                 1615                 1620             


Gln Asn  Leu Leu Thr Ser Ile  Glu Ser Glu Thr Ala  Ala Ser Glu 
    1625                 1630                 1635             


Glu Thr  Leu Phe Asn Ala Ser  Gln Arg Ile Ser Glu  Leu Glu Arg 
    1640                 1645                 1650             


Asn Val  Glu Glu Leu Lys Arg  Lys Ala Ala Gln Asn  Ser Gly Glu 
    1655                 1660                 1665             


Ala Glu  Tyr Ile Glu Lys Val  Val Tyr Thr Val Lys  Gln Ser Ala 
    1670                 1675                 1680             


Glu Asp  Val Lys Lys Thr Leu  Asp Gly Glu Leu Asp  Glu Lys Tyr 
    1685                 1690                 1695             


Lys Lys  Val Glu Asn Leu Ile  Ala Lys Lys Thr Glu  Glu Ser Ala 
    1700                 1705                 1710             


Asp Ala  Arg Arg Lys Ala Glu  Met Leu Gln Asn Glu  Ala Lys Thr 
    1715                 1720                 1725             


Leu Leu  Ala Gln Ala Asn Ser  Lys Leu Gln Leu Leu  Lys Asp Leu 
    1730                 1735                 1740             


Glu Arg  Lys Tyr Glu Asp Asn  Gln Arg Tyr Leu Glu  Asp Lys Ala 
    1745                 1750                 1755             


Gln Glu  Leu Ala Arg Leu Glu  Gly Glu Val Arg Ser  Leu Leu Lys 
    1760                 1765                 1770             


Asp Ile  Ser Gln Lys Val Ala  Val Tyr Ser Thr Cys  Leu 
    1775                 1780                 1785     


<210>  3257
<211>  845
<212>  PRT
<213>  homo sapiens

<400>  3257

Met Leu Ser Gly Val Trp Phe Leu Ser Val Leu Thr Val Ala Gly Ile 
1               5                   10                  15      


Leu Gln Thr Glu Ser Arg Lys Thr Ala Lys Asp Ile Cys Lys Ile Arg 
            20                  25                  30          


Cys Leu Cys Glu Glu Lys Glu Asn Val Leu Asn Ile Asn Cys Glu Asn 
        35                  40                  45              


Lys Gly Phe Thr Thr Val Ser Leu Leu Gln Pro Pro Gln Tyr Arg Ile 
    50                  55                  60                  


Tyr Gln Leu Phe Leu Asn Gly Asn Leu Leu Thr Arg Leu Tyr Pro Asn 
65                  70                  75                  80  


Glu Phe Val Asn Tyr Ser Asn Ala Val Thr Leu His Leu Gly Asn Asn 
                85                  90                  95      


Gly Leu Gln Glu Ile Arg Thr Gly Ala Phe Ser Gly Leu Lys Thr Leu 
            100                 105                 110         


Lys Arg Leu His Leu Asn Asn Asn Lys Leu Glu Ile Leu Arg Glu Asp 
        115                 120                 125             


Thr Phe Leu Gly Leu Glu Ser Leu Glu Tyr Leu Gln Ala Asp Tyr Asn 
    130                 135                 140                 


Tyr Ile Ser Ala Ile Glu Ala Gly Ala Phe Ser Lys Leu Asn Lys Leu 
145                 150                 155                 160 


Lys Val Leu Ile Leu Asn Asp Asn Leu Leu Leu Ser Leu Pro Ser Asn 
                165                 170                 175     


Val Phe Arg Phe Val Leu Leu Thr His Leu Asp Leu Arg Gly Asn Arg 
            180                 185                 190         


Leu Lys Val Met Pro Phe Ala Gly Val Leu Glu His Ile Gly Gly Ile 
        195                 200                 205             


Met Glu Ile Gln Leu Glu Glu Asn Pro Trp Asn Cys Thr Cys Asp Leu 
    210                 215                 220                 


Leu Pro Leu Lys Ala Trp Leu Asp Thr Ile Thr Val Phe Val Gly Glu 
225                 230                 235                 240 


Ile Val Cys Glu Thr Pro Phe Arg Leu His Gly Lys Asp Val Thr Gln 
                245                 250                 255     


Leu Thr Arg Gln Asp Leu Cys Pro Arg Lys Ser Ala Ser Asp Ser Ser 
            260                 265                 270         


Gln Arg Gly Ser His Ala Asp Thr His Val Gln Arg Leu Ser Pro Thr 
        275                 280                 285             


Met Asn Pro Ala Leu Asn Pro Thr Arg Ala Pro Lys Ala Ser Arg Pro 
    290                 295                 300                 


Pro Lys Met Arg Asn Arg Pro Thr Pro Arg Val Thr Val Ser Lys Asp 
305                 310                 315                 320 


Arg Gln Ser Phe Gly Pro Ile Met Val Tyr Gln Thr Lys Ser Pro Val 
                325                 330                 335     


Pro Leu Thr Cys Pro Ser Ser Cys Val Cys Thr Ser Gln Ser Ser Asp 
            340                 345                 350         


Asn Gly Leu Asn Val Asn Cys Gln Glu Arg Lys Phe Thr Asn Ile Ser 
        355                 360                 365             


Asp Leu Gln Pro Lys Pro Thr Ser Pro Lys Lys Leu Tyr Leu Thr Gly 
    370                 375                 380                 


Asn Tyr Leu Gln Thr Val Tyr Lys Asn Asp Leu Leu Glu Tyr Ser Ser 
385                 390                 395                 400 


Leu Asp Leu Leu His Leu Gly Asn Asn Arg Ile Ala Val Ile Gln Glu 
                405                 410                 415     


Gly Ala Phe Thr Asn Leu Thr Ser Leu Arg Arg Leu Tyr Leu Asn Gly 
            420                 425                 430         


Asn Tyr Leu Glu Val Leu Tyr Pro Ser Met Phe Asp Gly Leu Gln Ser 
        435                 440                 445             


Leu Gln Tyr Leu Tyr Leu Glu Tyr Asn Val Ile Lys Glu Ile Lys Pro 
    450                 455                 460                 


Leu Thr Phe Asp Ala Leu Ile Asn Leu Gln Leu Leu Phe Leu Asn Asn 
465                 470                 475                 480 


Asn Leu Leu Arg Ser Leu Pro Asp Asn Ile Phe Gly Gly Thr Ala Leu 
                485                 490                 495     


Thr Arg Leu Asn Leu Arg Asn Asn His Phe Ser His Leu Pro Val Lys 
            500                 505                 510         


Gly Val Leu Asp Gln Leu Pro Ala Phe Ile Gln Ile Asp Leu Gln Glu 
        515                 520                 525             


Asn Pro Trp Asp Cys Thr Cys Asp Ile Met Gly Leu Lys Asp Trp Thr 
    530                 535                 540                 


Glu His Ala Asn Ser Pro Val Ile Ile Asn Glu Val Thr Cys Glu Ser 
545                 550                 555                 560 


Pro Ala Lys His Ala Gly Glu Ile Leu Lys Phe Leu Gly Arg Glu Ala 
                565                 570                 575     


Ile Cys Pro Asp Ser Pro Asn Leu Ser Asp Gly Thr Val Leu Ser Met 
            580                 585                 590         


Asn His Asn Thr Asp Thr Pro Arg Ser Leu Ser Val Ser Pro Ser Ser 
        595                 600                 605             


Tyr Pro Glu Leu His Thr Glu Val Pro Leu Ser Val Leu Ile Leu Gly 
    610                 615                 620                 


Leu Leu Val Val Phe Ile Leu Ser Val Cys Phe Gly Ala Gly Leu Phe 
625                 630                 635                 640 


Val Phe Val Leu Lys Arg Arg Lys Gly Val Pro Ser Val Pro Arg Asn 
                645                 650                 655     


Thr Asn Asn Leu Asp Val Ser Ser Phe Gln Leu Gln Tyr Gly Ser Tyr 
            660                 665                 670         


Asn Thr Glu Thr His Asp Lys Thr Asp Gly His Val Tyr Asn Tyr Ile 
        675                 680                 685             


Pro Pro Pro Val Gly Gln Met Cys Gln Asn Pro Ile Tyr Met Gln Lys 
    690                 695                 700                 


Glu Gly Asp Pro Val Ala Tyr Tyr Arg Asn Leu Gln Glu Phe Ser Tyr 
705                 710                 715                 720 


Ser Asn Leu Glu Glu Lys Lys Glu Glu Pro Ala Thr Pro Ala Tyr Thr 
                725                 730                 735     


Ile Ser Ala Thr Glu Leu Leu Glu Lys Gln Ala Thr Pro Arg Glu Pro 
            740                 745                 750         


Glu Leu Leu Tyr Gln Asn Ile Ala Glu Arg Val Lys Glu Leu Pro Ser 
        755                 760                 765             


Ala Gly Leu Val His Tyr Asn Phe Cys Thr Leu Pro Lys Arg Gln Phe 
    770                 775                 780                 


Ala Pro Ser Tyr Glu Ser Arg Arg Gln Asn Gln Asp Arg Ile Asn Lys 
785                 790                 795                 800 


Thr Val Leu Tyr Gly Thr Pro Arg Lys Cys Phe Val Gly Gln Ser Lys 
                805                 810                 815     


Pro Asn His Pro Leu Leu Gln Ala Lys Pro Gln Ser Glu Pro Asp Tyr 
            820                 825                 830         


Leu Glu Val Leu Glu Lys Gln Thr Ala Ile Ser Gln Leu 
        835                 840                 845 


<210>  3258
<211>  845
<212>  PRT
<213>  homo sapiens

<400>  3258

Met Leu Ser Gly Val Trp Phe Leu Ser Val Leu Thr Val Ala Gly Ile 
1               5                   10                  15      


Leu Gln Thr Glu Ser Arg Lys Thr Ala Lys Asp Ile Cys Lys Ile Arg 
            20                  25                  30          


Cys Leu Cys Glu Glu Lys Glu Asn Val Leu Asn Ile Asn Cys Glu Asn 
        35                  40                  45              


Lys Gly Phe Thr Thr Val Ser Leu Leu Gln Pro Pro Gln Tyr Arg Ile 
    50                  55                  60                  


Tyr Gln Leu Phe Leu Asn Gly Asn Leu Leu Thr Arg Leu Tyr Pro Asn 
65                  70                  75                  80  


Glu Phe Val Asn Tyr Ser Asn Ala Val Thr Leu His Leu Gly Asn Asn 
                85                  90                  95      


Gly Leu Gln Glu Ile Arg Thr Gly Ala Phe Ser Gly Leu Lys Thr Leu 
            100                 105                 110         


Lys Arg Leu His Leu Asn Asn Asn Lys Leu Glu Ile Leu Arg Glu Asp 
        115                 120                 125             


Thr Phe Leu Gly Leu Glu Ser Leu Glu Tyr Leu Gln Ala Asp Tyr Asn 
    130                 135                 140                 


Tyr Ile Ser Ala Ile Glu Ala Gly Ala Phe Ser Lys Leu Asn Lys Leu 
145                 150                 155                 160 


Lys Val Leu Ile Leu Asn Asp Asn Leu Leu Leu Ser Leu Pro Ser Asn 
                165                 170                 175     


Val Phe Arg Phe Val Leu Leu Thr His Leu Asp Leu Arg Gly Asn Arg 
            180                 185                 190         


Leu Lys Val Met Pro Phe Ala Gly Val Leu Glu His Ile Gly Gly Ile 
        195                 200                 205             


Met Glu Ile Gln Leu Glu Glu Asn Pro Trp Asn Cys Thr Cys Asp Leu 
    210                 215                 220                 


Leu Pro Leu Lys Ala Trp Leu Asp Thr Ile Thr Val Phe Val Gly Glu 
225                 230                 235                 240 


Ile Val Cys Glu Thr Pro Phe Arg Leu His Gly Lys Asp Val Thr Gln 
                245                 250                 255     


Leu Thr Arg Gln Asp Leu Cys Pro Arg Lys Ser Ala Ser Asp Ser Ser 
            260                 265                 270         


Gln Arg Gly Ser His Ala Asp Thr His Val Gln Arg Leu Ser Pro Thr 
        275                 280                 285             


Met Asn Pro Ala Leu Asn Pro Thr Arg Ala Pro Lys Ala Ser Arg Pro 
    290                 295                 300                 


Pro Lys Met Arg Asn Arg Pro Thr Pro Arg Val Thr Val Ser Lys Asp 
305                 310                 315                 320 


Arg Gln Ser Phe Gly Pro Ile Met Val Tyr Gln Thr Lys Ser Pro Val 
                325                 330                 335     


Pro Leu Thr Cys Pro Ser Ser Cys Val Cys Thr Ser Gln Ser Ser Asp 
            340                 345                 350         


Asn Gly Leu Asn Val Asn Cys Gln Glu Arg Lys Phe Thr Asn Ile Ser 
        355                 360                 365             


Asp Leu Gln Pro Lys Pro Thr Ser Pro Lys Lys Leu Tyr Leu Thr Gly 
    370                 375                 380                 


Asn Tyr Leu Gln Thr Val Tyr Lys Asn Asp Leu Leu Glu Tyr Ser Ser 
385                 390                 395                 400 


Leu Asp Leu Leu His Leu Gly Asn Asn Arg Ile Ala Val Ile Gln Glu 
                405                 410                 415     


Gly Ala Phe Thr Asn Leu Thr Ser Leu Arg Arg Leu Tyr Leu Asn Gly 
            420                 425                 430         


Asn Tyr Leu Glu Val Leu Tyr Pro Ser Met Phe Asp Gly Leu Gln Ser 
        435                 440                 445             


Leu Gln Tyr Leu Tyr Leu Glu Tyr Asn Val Ile Lys Glu Ile Lys Pro 
    450                 455                 460                 


Leu Thr Phe Asp Ala Leu Ile Asn Leu Gln Leu Leu Phe Leu Asn Asn 
465                 470                 475                 480 


Asn Leu Leu Arg Ser Leu Pro Asp Asn Ile Phe Gly Gly Thr Ala Leu 
                485                 490                 495     


Thr Arg Leu Asn Leu Arg Asn Asn His Phe Ser His Leu Pro Val Lys 
            500                 505                 510         


Gly Val Leu Asp Gln Leu Pro Ala Phe Ile Gln Ile Asp Leu Gln Glu 
        515                 520                 525             


Asn Pro Trp Asp Cys Thr Cys Asp Ile Met Gly Leu Lys Asp Trp Thr 
    530                 535                 540                 


Glu His Ala Asn Ser Pro Val Ile Ile Asn Glu Val Thr Cys Glu Ser 
545                 550                 555                 560 


Pro Ala Lys His Ala Gly Glu Ile Leu Lys Phe Leu Gly Arg Glu Ala 
                565                 570                 575     


Ile Cys Pro Asp Ser Pro Asn Leu Ser Asp Gly Thr Val Leu Ser Met 
            580                 585                 590         


Asn His Asn Thr Asp Thr Pro Arg Ser Leu Ser Val Ser Pro Ser Ser 
        595                 600                 605             


Tyr Pro Glu Leu His Thr Glu Val Pro Leu Ser Val Leu Ile Leu Gly 
    610                 615                 620                 


Leu Leu Val Val Phe Ile Leu Ser Val Cys Phe Gly Ala Gly Leu Phe 
625                 630                 635                 640 


Val Phe Val Leu Lys Arg Arg Lys Gly Val Pro Ser Val Pro Arg Asn 
                645                 650                 655     


Thr Asn Asn Leu Asp Val Ser Ser Phe Gln Leu Gln Tyr Gly Ser Tyr 
            660                 665                 670         


Asn Thr Glu Thr His Asp Lys Thr Asp Gly His Val Tyr Asn Tyr Ile 
        675                 680                 685             


Pro Pro Pro Val Gly Gln Met Cys Gln Asn Pro Ile Tyr Met Gln Lys 
    690                 695                 700                 


Glu Gly Asp Pro Val Ala Tyr Tyr Arg Asn Leu Gln Glu Phe Ser Tyr 
705                 710                 715                 720 


Ser Asn Leu Glu Glu Lys Lys Glu Glu Pro Ala Thr Pro Ala Tyr Thr 
                725                 730                 735     


Ile Ser Ala Thr Glu Leu Leu Glu Lys Gln Ala Thr Pro Arg Glu Pro 
            740                 745                 750         


Glu Leu Leu Tyr Gln Asn Ile Ala Glu Arg Val Lys Glu Leu Pro Ser 
        755                 760                 765             


Ala Gly Leu Val His Tyr Asn Phe Cys Thr Leu Pro Lys Arg Gln Phe 
    770                 775                 780                 


Ala Pro Ser Tyr Glu Ser Arg Arg Gln Asn Gln Asp Arg Ile Asn Lys 
785                 790                 795                 800 


Thr Val Leu Tyr Gly Thr Pro Arg Lys Cys Phe Val Gly Gln Ser Lys 
                805                 810                 815     


Pro Asn His Pro Leu Leu Gln Ala Lys Pro Gln Ser Glu Pro Asp Tyr 
            820                 825                 830         


Leu Glu Val Leu Glu Lys Gln Thr Ala Ile Ser Gln Leu 
        835                 840                 845 


<210>  3259
<211>  845
<212>  PRT
<213>  homo sapiens

<400>  3259

Met Leu Ser Gly Val Trp Phe Leu Ser Val Leu Thr Val Ala Gly Ile 
1               5                   10                  15      


Leu Gln Thr Glu Ser Arg Lys Thr Ala Lys Asp Ile Cys Lys Ile Arg 
            20                  25                  30          


Cys Leu Cys Glu Glu Lys Glu Asn Val Leu Asn Ile Asn Cys Glu Asn 
        35                  40                  45              


Lys Gly Phe Thr Thr Val Ser Leu Leu Gln Pro Pro Gln Tyr Arg Ile 
    50                  55                  60                  


Tyr Gln Leu Phe Leu Asn Gly Asn Leu Leu Thr Arg Leu Tyr Pro Asn 
65                  70                  75                  80  


Glu Phe Val Asn Tyr Ser Asn Ala Val Thr Leu His Leu Gly Asn Asn 
                85                  90                  95      


Gly Leu Gln Glu Ile Arg Thr Gly Ala Phe Ser Gly Leu Lys Thr Leu 
            100                 105                 110         


Lys Arg Leu His Leu Asn Asn Asn Lys Leu Glu Ile Leu Arg Glu Asp 
        115                 120                 125             


Thr Phe Leu Gly Leu Glu Ser Leu Glu Tyr Leu Gln Ala Asp Tyr Asn 
    130                 135                 140                 


Tyr Ile Ser Ala Ile Glu Ala Gly Ala Phe Ser Lys Leu Asn Lys Leu 
145                 150                 155                 160 


Lys Val Leu Ile Leu Asn Asp Asn Leu Leu Leu Ser Leu Pro Ser Asn 
                165                 170                 175     


Val Phe Arg Phe Val Leu Leu Thr His Leu Asp Leu Arg Gly Asn Arg 
            180                 185                 190         


Leu Lys Val Met Pro Phe Ala Gly Val Leu Glu His Ile Gly Gly Ile 
        195                 200                 205             


Met Glu Ile Gln Leu Glu Glu Asn Pro Trp Asn Cys Thr Cys Asp Leu 
    210                 215                 220                 


Leu Pro Leu Lys Ala Trp Leu Asp Thr Ile Thr Val Phe Val Gly Glu 
225                 230                 235                 240 


Ile Val Cys Glu Thr Pro Phe Arg Leu His Gly Lys Asp Val Thr Gln 
                245                 250                 255     


Leu Thr Arg Gln Asp Leu Cys Pro Arg Lys Ser Ala Ser Asp Ser Ser 
            260                 265                 270         


Gln Arg Gly Ser His Ala Asp Thr His Val Gln Arg Leu Ser Pro Thr 
        275                 280                 285             


Met Asn Pro Ala Leu Asn Pro Thr Arg Ala Pro Lys Ala Ser Arg Pro 
    290                 295                 300                 


Pro Lys Met Arg Asn Arg Pro Thr Pro Arg Val Thr Val Ser Lys Asp 
305                 310                 315                 320 


Arg Gln Ser Phe Gly Pro Ile Met Val Tyr Gln Thr Lys Ser Pro Val 
                325                 330                 335     


Pro Leu Thr Cys Pro Ser Ser Cys Val Cys Thr Ser Gln Ser Ser Asp 
            340                 345                 350         


Asn Gly Leu Asn Val Asn Cys Gln Glu Arg Lys Phe Thr Asn Ile Ser 
        355                 360                 365             


Asp Leu Gln Pro Lys Pro Thr Ser Pro Lys Lys Leu Tyr Leu Thr Gly 
    370                 375                 380                 


Asn Tyr Leu Gln Thr Val Tyr Lys Asn Asp Leu Leu Glu Tyr Ser Ser 
385                 390                 395                 400 


Leu Asp Leu Leu His Leu Gly Asn Asn Arg Ile Ala Val Ile Gln Glu 
                405                 410                 415     


Gly Ala Phe Thr Asn Leu Thr Ser Leu Arg Arg Leu Tyr Leu Asn Gly 
            420                 425                 430         


Asn Tyr Leu Glu Val Leu Tyr Pro Ser Met Phe Asp Gly Leu Gln Ser 
        435                 440                 445             


Leu Gln Tyr Leu Tyr Leu Glu Tyr Asn Val Ile Lys Glu Ile Lys Pro 
    450                 455                 460                 


Leu Thr Phe Asp Ala Leu Ile Asn Leu Gln Leu Leu Phe Leu Asn Asn 
465                 470                 475                 480 


Asn Leu Leu Arg Ser Leu Pro Asp Asn Ile Phe Gly Gly Thr Ala Leu 
                485                 490                 495     


Thr Arg Leu Asn Leu Arg Asn Asn His Phe Ser His Leu Pro Val Lys 
            500                 505                 510         


Gly Val Leu Asp Gln Leu Pro Ala Phe Ile Gln Ile Asp Leu Gln Glu 
        515                 520                 525             


Asn Pro Trp Asp Cys Thr Cys Asp Ile Met Gly Leu Lys Asp Trp Thr 
    530                 535                 540                 


Glu His Ala Asn Ser Pro Val Ile Ile Asn Glu Val Thr Cys Glu Ser 
545                 550                 555                 560 


Pro Ala Lys His Ala Gly Glu Ile Leu Lys Phe Leu Gly Arg Glu Ala 
                565                 570                 575     


Ile Cys Pro Asp Ser Pro Asn Leu Ser Asp Gly Thr Val Leu Ser Met 
            580                 585                 590         


Asn His Asn Thr Asp Thr Pro Arg Ser Leu Ser Val Ser Pro Ser Ser 
        595                 600                 605             


Tyr Pro Glu Leu His Thr Glu Val Pro Leu Ser Val Leu Ile Leu Gly 
    610                 615                 620                 


Leu Leu Val Val Phe Ile Leu Ser Val Cys Phe Gly Ala Gly Leu Phe 
625                 630                 635                 640 


Val Phe Val Leu Lys Arg Arg Lys Gly Val Pro Ser Val Pro Arg Asn 
                645                 650                 655     


Thr Asn Asn Leu Asp Val Ser Ser Phe Gln Leu Gln Tyr Gly Ser Tyr 
            660                 665                 670         


Asn Thr Glu Thr His Asp Lys Thr Asp Gly His Val Tyr Asn Tyr Ile 
        675                 680                 685             


Pro Pro Pro Val Gly Gln Met Cys Gln Asn Pro Ile Tyr Met Gln Lys 
    690                 695                 700                 


Glu Gly Asp Pro Val Ala Tyr Tyr Arg Asn Leu Gln Glu Phe Ser Tyr 
705                 710                 715                 720 


Ser Asn Leu Glu Glu Lys Lys Glu Glu Pro Ala Thr Pro Ala Tyr Thr 
                725                 730                 735     


Ile Ser Ala Thr Glu Leu Leu Glu Lys Gln Ala Thr Pro Arg Glu Pro 
            740                 745                 750         


Glu Leu Leu Tyr Gln Asn Ile Ala Glu Arg Val Lys Glu Leu Pro Ser 
        755                 760                 765             


Ala Gly Leu Val His Tyr Asn Phe Cys Thr Leu Pro Lys Arg Gln Phe 
    770                 775                 780                 


Ala Pro Ser Tyr Glu Ser Arg Arg Gln Asn Gln Asp Arg Ile Asn Lys 
785                 790                 795                 800 


Thr Val Leu Tyr Gly Thr Pro Arg Lys Cys Phe Val Gly Gln Ser Lys 
                805                 810                 815     


Pro Asn His Pro Leu Leu Gln Ala Lys Pro Gln Ser Glu Pro Asp Tyr 
            820                 825                 830         


Leu Glu Val Leu Glu Lys Gln Thr Ala Ile Ser Gln Leu 
        835                 840                 845 


<210>  3260
<211>  845
<212>  PRT
<213>  homo sapiens

<400>  3260

Met Leu Ser Gly Val Trp Phe Leu Ser Val Leu Thr Val Ala Gly Ile 
1               5                   10                  15      


Leu Gln Thr Glu Ser Arg Lys Thr Ala Lys Asp Ile Cys Lys Ile Arg 
            20                  25                  30          


Cys Leu Cys Glu Glu Lys Glu Asn Val Leu Asn Ile Asn Cys Glu Asn 
        35                  40                  45              


Lys Gly Phe Thr Thr Val Ser Leu Leu Gln Pro Pro Gln Tyr Arg Ile 
    50                  55                  60                  


Tyr Gln Leu Phe Leu Asn Gly Asn Leu Leu Thr Arg Leu Tyr Pro Asn 
65                  70                  75                  80  


Glu Phe Val Asn Tyr Ser Asn Ala Val Thr Leu His Leu Gly Asn Asn 
                85                  90                  95      


Gly Leu Gln Glu Ile Arg Thr Gly Ala Phe Ser Gly Leu Lys Thr Leu 
            100                 105                 110         


Lys Arg Leu His Leu Asn Asn Asn Lys Leu Glu Ile Leu Arg Glu Asp 
        115                 120                 125             


Thr Phe Leu Gly Leu Glu Ser Leu Glu Tyr Leu Gln Ala Asp Tyr Asn 
    130                 135                 140                 


Tyr Ile Ser Ala Ile Glu Ala Gly Ala Phe Ser Lys Leu Asn Lys Leu 
145                 150                 155                 160 


Lys Val Leu Ile Leu Asn Asp Asn Leu Leu Leu Ser Leu Pro Ser Asn 
                165                 170                 175     


Val Phe Arg Phe Val Leu Leu Thr His Leu Asp Leu Arg Gly Asn Arg 
            180                 185                 190         


Leu Lys Val Met Pro Phe Ala Gly Val Leu Glu His Ile Gly Gly Ile 
        195                 200                 205             


Met Glu Ile Gln Leu Glu Glu Asn Pro Trp Asn Cys Thr Cys Asp Leu 
    210                 215                 220                 


Leu Pro Leu Lys Ala Trp Leu Asp Thr Ile Thr Val Phe Val Gly Glu 
225                 230                 235                 240 


Ile Val Cys Glu Thr Pro Phe Arg Leu His Gly Lys Asp Val Thr Gln 
                245                 250                 255     


Leu Thr Arg Gln Asp Leu Cys Pro Arg Lys Ser Ala Ser Asp Ser Ser 
            260                 265                 270         


Gln Arg Gly Ser His Ala Asp Thr His Val Gln Arg Leu Ser Pro Thr 
        275                 280                 285             


Met Asn Pro Ala Leu Asn Pro Thr Arg Ala Pro Lys Ala Ser Arg Pro 
    290                 295                 300                 


Pro Lys Met Arg Asn Arg Pro Thr Pro Arg Val Thr Val Ser Lys Asp 
305                 310                 315                 320 


Arg Gln Ser Phe Gly Pro Ile Met Val Tyr Gln Thr Lys Ser Pro Val 
                325                 330                 335     


Pro Leu Thr Cys Pro Ser Ser Cys Val Cys Thr Ser Gln Ser Ser Asp 
            340                 345                 350         


Asn Gly Leu Asn Val Asn Cys Gln Glu Arg Lys Phe Thr Asn Ile Ser 
        355                 360                 365             


Asp Leu Gln Pro Lys Pro Thr Ser Pro Lys Lys Leu Tyr Leu Thr Gly 
    370                 375                 380                 


Asn Tyr Leu Gln Thr Val Tyr Lys Asn Asp Leu Leu Glu Tyr Ser Ser 
385                 390                 395                 400 


Leu Asp Leu Leu His Leu Gly Asn Asn Arg Ile Ala Val Ile Gln Glu 
                405                 410                 415     


Gly Ala Phe Thr Asn Leu Thr Ser Leu Arg Arg Leu Tyr Leu Asn Gly 
            420                 425                 430         


Asn Tyr Leu Glu Val Leu Tyr Pro Ser Met Phe Asp Gly Leu Gln Ser 
        435                 440                 445             


Leu Gln Tyr Leu Tyr Leu Glu Tyr Asn Val Ile Lys Glu Ile Lys Pro 
    450                 455                 460                 


Leu Thr Phe Asp Ala Leu Ile Asn Leu Gln Leu Leu Phe Leu Asn Asn 
465                 470                 475                 480 


Asn Leu Leu Arg Ser Leu Pro Asp Asn Ile Phe Gly Gly Thr Ala Leu 
                485                 490                 495     


Thr Arg Leu Asn Leu Arg Asn Asn His Phe Ser His Leu Pro Val Lys 
            500                 505                 510         


Gly Val Leu Asp Gln Leu Pro Ala Phe Ile Gln Ile Asp Leu Gln Glu 
        515                 520                 525             


Asn Pro Trp Asp Cys Thr Cys Asp Ile Met Gly Leu Lys Asp Trp Thr 
    530                 535                 540                 


Glu His Ala Asn Ser Pro Val Ile Ile Asn Glu Val Thr Cys Glu Ser 
545                 550                 555                 560 


Pro Ala Lys His Ala Gly Glu Ile Leu Lys Phe Leu Gly Arg Glu Ala 
                565                 570                 575     


Ile Cys Pro Asp Ser Pro Asn Leu Ser Asp Gly Thr Val Leu Ser Met 
            580                 585                 590         


Asn His Asn Thr Asp Thr Pro Arg Ser Leu Ser Val Ser Pro Ser Ser 
        595                 600                 605             


Tyr Pro Glu Leu His Thr Glu Val Pro Leu Ser Val Leu Ile Leu Gly 
    610                 615                 620                 


Leu Leu Val Val Phe Ile Leu Ser Val Cys Phe Gly Ala Gly Leu Phe 
625                 630                 635                 640 


Val Phe Val Leu Lys Arg Arg Lys Gly Val Pro Ser Val Pro Arg Asn 
                645                 650                 655     


Thr Asn Asn Leu Asp Val Ser Ser Phe Gln Leu Gln Tyr Gly Ser Tyr 
            660                 665                 670         


Asn Thr Glu Thr His Asp Lys Thr Asp Gly His Val Tyr Asn Tyr Ile 
        675                 680                 685             


Pro Pro Pro Val Gly Gln Met Cys Gln Asn Pro Ile Tyr Met Gln Lys 
    690                 695                 700                 


Glu Gly Asp Pro Val Ala Tyr Tyr Arg Asn Leu Gln Glu Phe Ser Tyr 
705                 710                 715                 720 


Ser Asn Leu Glu Glu Lys Lys Glu Glu Pro Ala Thr Pro Ala Tyr Thr 
                725                 730                 735     


Ile Ser Ala Thr Glu Leu Leu Glu Lys Gln Ala Thr Pro Arg Glu Pro 
            740                 745                 750         


Glu Leu Leu Tyr Gln Asn Ile Ala Glu Arg Val Lys Glu Leu Pro Ser 
        755                 760                 765             


Ala Gly Leu Val His Tyr Asn Phe Cys Thr Leu Pro Lys Arg Gln Phe 
    770                 775                 780                 


Ala Pro Ser Tyr Glu Ser Arg Arg Gln Asn Gln Asp Arg Ile Asn Lys 
785                 790                 795                 800 


Thr Val Leu Tyr Gly Thr Pro Arg Lys Cys Phe Val Gly Gln Ser Lys 
                805                 810                 815     


Pro Asn His Pro Leu Leu Gln Ala Lys Pro Gln Ser Glu Pro Asp Tyr 
            820                 825                 830         


Leu Glu Val Leu Glu Lys Gln Thr Ala Ile Ser Gln Leu 
        835                 840                 845 


<210>  3261
<211>  425
<212>  PRT
<213>  homo sapiens

<400>  3261

Met Ser Ser Ile Leu Pro Phe Thr Pro Pro Ile Val Lys Arg Leu Leu 
1               5                   10                  15      


Gly Trp Lys Lys Gly Glu Gln Asn Gly Gln Glu Glu Lys Trp Cys Glu 
            20                  25                  30          


Lys Ala Val Lys Ser Leu Val Lys Lys Leu Lys Lys Thr Gly Gln Leu 
        35                  40                  45              


Asp Glu Leu Glu Lys Ala Ile Thr Thr Gln Asn Val Asn Thr Lys Cys 
    50                  55                  60                  


Ile Thr Ile Pro Arg Ser Leu Asp Gly Arg Leu Gln Val Ser His Arg 
65                  70                  75                  80  


Lys Gly Leu Pro His Val Ile Tyr Cys Arg Leu Trp Arg Trp Pro Asp 
                85                  90                  95      


Leu His Ser His His Glu Leu Arg Ala Met Glu Leu Cys Glu Phe Ala 
            100                 105                 110         


Phe Asn Met Lys Lys Asp Glu Val Cys Val Asn Pro Tyr His Tyr Gln 
        115                 120                 125             


Arg Val Glu Thr Pro Val Leu Pro Pro Val Leu Val Pro Arg His Thr 
    130                 135                 140                 


Glu Ile Pro Ala Glu Phe Pro Pro Leu Asp Asp Tyr Ser His Ser Ile 
145                 150                 155                 160 


Pro Glu Asn Thr Asn Phe Pro Ala Gly Ile Glu Pro Gln Ser Asn Ile 
                165                 170                 175     


Pro Glu Thr Pro Pro Pro Gly Tyr Leu Ser Glu Asp Gly Glu Thr Ser 
            180                 185                 190         


Asp His Gln Met Asn His Ser Met Asp Ala Gly Ser Pro Asn Leu Ser 
        195                 200                 205             


Pro Asn Pro Met Ser Pro Ala His Asn Asn Leu Asp Leu Gln Pro Val 
    210                 215                 220                 


Thr Tyr Cys Glu Pro Ala Phe Trp Cys Ser Ile Ser Tyr Tyr Glu Leu 
225                 230                 235                 240 


Asn Gln Arg Val Gly Glu Thr Phe His Ala Ser Gln Pro Ser Met Thr 
                245                 250                 255     


Val Asp Gly Phe Thr Asp Pro Ser Asn Ser Glu Arg Phe Cys Leu Gly 
            260                 265                 270         


Leu Leu Ser Asn Val Asn Arg Asn Ala Ala Val Glu Leu Thr Arg Arg 
        275                 280                 285             


His Ile Gly Arg Gly Val Arg Leu Tyr Tyr Ile Gly Gly Glu Val Phe 
    290                 295                 300                 


Ala Glu Cys Leu Ser Asp Ser Ala Ile Phe Val Gln Ser Pro Asn Cys 
305                 310                 315                 320 


Asn Gln Arg Tyr Gly Trp His Pro Ala Thr Val Cys Lys Ile Pro Pro 
                325                 330                 335     


Gly Cys Asn Leu Lys Ile Phe Asn Asn Gln Glu Phe Ala Ala Leu Leu 
            340                 345                 350         


Ala Gln Ser Val Asn Gln Gly Phe Glu Ala Val Tyr Gln Leu Thr Arg 
        355                 360                 365             


Met Cys Thr Ile Arg Met Ser Phe Val Lys Gly Trp Gly Ala Glu Tyr 
    370                 375                 380                 


Arg Arg Gln Thr Val Thr Ser Thr Pro Cys Trp Ile Glu Leu His Leu 
385                 390                 395                 400 


Asn Gly Pro Leu Gln Trp Leu Asp Lys Val Leu Thr Gln Met Gly Ser 
                405                 410                 415     


Pro Ser Ile Arg Cys Ser Ser Val Ser 
            420                 425 


<210>  3262
<211>  471
<212>  PRT
<213>  homo sapiens

<400>  3262

Met Asn Met Ala Asn Phe Leu Arg Gly Phe Glu Glu Lys Gly Ile Lys 
1               5                   10                  15      


Asn Asp Arg Pro Glu Asp Gln Leu Ser Lys Glu Lys Lys Lys Ile Leu 
            20                  25                  30          


Phe Ser Phe Cys Glu Val Cys Asn Ile Gln Leu Asn Ser Ala Ala Gln 
        35                  40                  45              


Ala Gln Val His Ser Asn Gly Lys Ser His Arg Lys Arg Val Lys Gln 
    50                  55                  60                  


Leu Ser Asp Gly Gln Pro Pro Pro Pro Ala Gln Ala Ser Pro Ser Ser 
65                  70                  75                  80  


Asn Ser Ser Thr Gly Ser Thr Cys His Thr Thr Thr Leu Pro Ala Leu 
                85                  90                  95      


Val Arg Thr Pro Thr Leu Met Met Gln Pro Ser Leu Asp Ile Lys Pro 
            100                 105                 110         


Phe Met Ser Phe Pro Val Asp Ser Ser Ser Ala Val Gly Leu Phe Pro 
        115                 120                 125             


Asn Phe Asn Thr Met Asp Pro Val Gln Lys Ala Val Ile Asn His Thr 
    130                 135                 140                 


Phe Gly Val Ser Ile Pro Pro Lys Lys Lys Gln Val Ile Ser Cys Asn 
145                 150                 155                 160 


Val Cys Gln Leu Arg Phe Asn Ser Asp Ser Gln Ala Glu Ala His Tyr 
                165                 170                 175     


Lys Gly Ser Lys His Ala Lys Lys Val Lys Ala Leu Asp Ala Thr Lys 
            180                 185                 190         


Asn Lys Pro Lys Met Val Pro Ser Lys Asp Ser Ala Lys Ala Asn Pro 
        195                 200                 205             


Ser Cys Ser Ile Thr Pro Ile Thr Gly Asn Asn Ser Asp Lys Ser Glu 
    210                 215                 220                 


Asp Lys Gly Lys Leu Lys Ala Ser Ser Ser Ser Gln Pro Ser Ser Ser 
225                 230                 235                 240 


Glu Ser Gly Ser Phe Leu Leu Lys Ser Gly Thr Thr Pro Leu Pro Pro 
                245                 250                 255     


Gly Ala Ala Thr Ser Pro Ser Lys Ser Thr Asn Gly Ala Pro Gly Thr 
            260                 265                 270         


Val Val Glu Ser Glu Glu Glu Lys Ala Lys Lys Leu Leu Tyr Cys Ser 
        275                 280                 285             


Leu Cys Lys Val Ala Val Asn Ser Leu Ser Gln Leu Glu Ala His Asn 
    290                 295                 300                 


Thr Gly Ser Lys His Lys Thr Met Val Glu Ala Arg Asn Gly Ala Gly 
305                 310                 315                 320 


Pro Ile Lys Ser Tyr Pro Arg Pro Gly Ser Arg Leu Lys Met Gln Asn 
                325                 330                 335     


Gly Ser Lys Gly Ser Gly Leu Gln Asn Lys Thr Phe His Cys Glu Ile 
            340                 345                 350         


Cys Asp Val His Val Asn Ser Glu Ile Gln Leu Lys Gln His Ile Ser 
        355                 360                 365             


Ser Arg Arg His Lys Asp Arg Val Ala Gly Lys Pro Leu Lys Pro Lys 
    370                 375                 380                 


Tyr Ser Pro Tyr Asn Lys Leu Gln Arg Ser Pro Ser Ile Leu Ala Ala 
385                 390                 395                 400 


Lys Leu Ala Phe Gln Lys Asp Met Met Lys Pro Leu Ala Pro Ala Phe 
                405                 410                 415     


Leu Ser Ser Pro Leu Ala Ala Ala Ala Ala Val Ser Ser Ala Leu Ser 
            420                 425                 430         


Leu Pro Pro Arg Pro Ser Ala Ser Leu Phe Gln Ala Pro Ala Ile Pro 
        435                 440                 445             


Pro Ala Leu Leu Arg Pro Gly His Gly Pro Ile Arg Ala Thr Pro Ala 
    450                 455                 460                 


Ser Ile Leu Phe Ala Pro Tyr 
465                 470     


<210>  3263
<211>  217
<212>  PRT
<213>  homo sapiens

<400>  3263

Met Ser Phe Arg Gly Gly Gly Arg Gly Gly Phe Asn Arg Gly Gly Gly 
1               5                   10                  15      


Gly Gly Gly Phe Asn Arg Gly Gly Ser Ser Asn His Phe Arg Gly Gly 
            20                  25                  30          


Gly Gly Gly Gly Gly Gly Gly Asn Phe Arg Gly Gly Gly Arg Gly Gly 
        35                  40                  45              


Phe Gly Arg Gly Gly Gly Arg Gly Gly Phe Asn Lys Gly Gln Asp Gln 
    50                  55                  60                  


Gly Pro Pro Glu Arg Val Val Leu Leu Gly Glu Phe Leu His Pro Cys 
65                  70                  75                  80  


Glu Asp Asp Ile Val Cys Lys Cys Thr Thr Asp Glu Asn Lys Val Pro 
                85                  90                  95      


Tyr Phe Asn Ala Pro Val Tyr Leu Glu Asn Lys Glu Gln Ile Gly Lys 
            100                 105                 110         


Val Asp Glu Ile Phe Gly Gln Leu Arg Asp Phe Tyr Phe Ser Val Lys 
        115                 120                 125             


Leu Ser Glu Asn Met Lys Ala Ser Ser Phe Lys Lys Leu Gln Lys Phe 
    130                 135                 140                 


Tyr Ile Asp Pro Tyr Lys Leu Leu Pro Leu Gln Arg Phe Leu Pro Arg 
145                 150                 155                 160 


Pro Pro Gly Glu Lys Gly Pro Pro Arg Gly Gly Gly Arg Gly Gly Arg 
                165                 170                 175     


Gly Gly Gly Arg Gly Gly Gly Gly Arg Gly Gly Gly Arg Gly Gly Gly 
            180                 185                 190         


Phe Arg Gly Gly Arg Gly Gly Gly Gly Gly Gly Phe Arg Gly Gly Arg 
        195                 200                 205             


Gly Gly Gly Phe Arg Gly Arg Gly His 
    210                 215         


<210>  3264
<211>  327
<212>  PRT
<213>  homo sapiens

<400>  3264

Met Thr Met Glu Ser Gly Ala Glu Asn Gln Gln Ser Gly Asp Ala Ala 
1               5                   10                  15      


Val Thr Glu Ala Glu Asn Gln Gln Met Thr Val Gln Ala Gln Pro Gln 
            20                  25                  30          


Ile Ala Thr Leu Ala Gln Val Ser Met Pro Ala Ala His Ala Thr Ser 
        35                  40                  45              


Ser Ala Pro Thr Val Thr Leu Val Gln Leu Pro Asn Gly Gln Thr Val 
    50                  55                  60                  


Gln Val His Gly Val Ile Gln Ala Ala Gln Pro Ser Val Ile Gln Ser 
65                  70                  75                  80  


Pro Gln Val Gln Thr Val Gln Ile Ser Thr Ile Ala Glu Ser Glu Asp 
                85                  90                  95      


Ser Gln Glu Ser Val Asp Ser Val Thr Asp Ser Gln Lys Arg Arg Glu 
            100                 105                 110         


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Asp Leu Ser 
        115                 120                 125             


Ser Asp Ala Pro Gly Val Pro Arg Ile Glu Glu Glu Lys Ser Glu Glu 
    130                 135                 140                 


Glu Thr Ser Ala Pro Ala Ile Thr Thr Val Thr Val Pro Thr Pro Ile 
145                 150                 155                 160 


Tyr Gln Thr Ser Ser Gly Gln Tyr Ile Ala Ile Thr Gln Gly Gly Ala 
                165                 170                 175     


Ile Gln Leu Ala Asn Asn Gly Thr Asp Gly Val Gln Gly Leu Gln Thr 
            180                 185                 190         


Leu Thr Met Thr Asn Ala Ala Ala Thr Gln Pro Gly Thr Thr Ile Leu 
        195                 200                 205             


Gln Tyr Ala Gln Thr Thr Asp Gly Gln Gln Ile Leu Val Pro Ser Asn 
    210                 215                 220                 


Gln Val Val Val Gln Ala Ala Ser Gly Asp Val Gln Thr Tyr Gln Ile 
225                 230                 235                 240 


Arg Thr Ala Pro Thr Ser Thr Ile Ala Pro Gly Val Val Met Ala Ser 
                245                 250                 255     


Ser Pro Ala Leu Pro Thr Gln Pro Ala Glu Glu Ala Ala Arg Lys Arg 
            260                 265                 270         


Glu Val Arg Leu Met Lys Asn Arg Glu Ala Ala Arg Glu Cys Arg Arg 
        275                 280                 285             


Lys Lys Lys Glu Tyr Val Lys Cys Leu Glu Asn Arg Val Ala Val Leu 
    290                 295                 300                 


Glu Asn Gln Asn Lys Thr Leu Ile Glu Glu Leu Lys Ala Leu Lys Asp 
305                 310                 315                 320 


Leu Tyr Cys His Lys Ser Asp 
                325         


<210>  3265
<211>  467
<212>  PRT
<213>  homo sapiens

<400>  3265

Met Thr Met Leu Leu Asp Gly Gly Pro Gln Phe Pro Gly Leu Gly Val 
1               5                   10                  15      


Gly Ser Phe Gly Ala Pro Arg His His Glu Met Pro Asn Arg Glu Pro 
            20                  25                  30          


Ala Gly Met Gly Leu Asn Pro Phe Gly Asp Ser Thr His Ala Ala Ala 
        35                  40                  45              


Ala Ala Ala Ala Ala Ala Ala Phe Lys Leu Ser Pro Ala Ala Ala His 
    50                  55                  60                  


Asp Leu Ser Ser Gly Gln Ser Ser Ala Phe Thr Pro Gln Gly Ser Gly 
65                  70                  75                  80  


Tyr Ala Asn Ala Leu Gly His His His His His His His His His His 
                85                  90                  95      


His Thr Ser Gln Val Pro Ser Tyr Gly Gly Ala Ala Ser Ala Ala Phe 
            100                 105                 110         


Asn Ser Thr Arg Glu Phe Leu Phe Arg Gln Arg Ser Ser Gly Leu Ser 
        115                 120                 125             


Glu Ala Ala Ser Gly Gly Gly Gln His Gly Leu Phe Ala Gly Ser Ala 
    130                 135                 140                 


Ser Ser Leu His Ala Pro Ala Gly Ile Pro Glu Pro Pro Ser Tyr Leu 
145                 150                 155                 160 


Leu Phe Pro Gly Leu His Glu Gln Gly Ala Gly His Pro Ser Pro Thr 
                165                 170                 175     


Gly His Val Asp Asn Asn Gln Val His Leu Gly Leu Arg Gly Glu Leu 
            180                 185                 190         


Phe Gly Arg Ala Asp Pro Tyr Arg Pro Val Ala Ser Pro Arg Thr Asp 
        195                 200                 205             


Pro Tyr Ala Ala Gly Ala Gln Phe Pro Asn Tyr Ser Pro Met Asn Met 
    210                 215                 220                 


Asn Met Gly Val Asn Val Ala Ala His His Gly Pro Gly Ala Phe Phe 
225                 230                 235                 240 


Arg Tyr Met Arg Gln Pro Ile Lys Gln Glu Leu Ser Cys Lys Trp Ile 
                245                 250                 255     


Asp Glu Ala Gln Leu Ser Arg Pro Lys Lys Ser Cys Asp Arg Thr Phe 
            260                 265                 270         


Ser Thr Met His Glu Leu Val Thr His Val Thr Met Glu His Val Gly 
        275                 280                 285             


Gly Pro Glu Gln Asn Asn His Val Cys Tyr Trp Glu Glu Cys Pro Arg 
    290                 295                 300                 


Glu Gly Lys Ser Phe Lys Ala Lys Tyr Lys Leu Val Asn His Ile Arg 
305                 310                 315                 320 


Val His Thr Gly Glu Lys Pro Phe Pro Cys Pro Phe Pro Gly Cys Gly 
                325                 330                 335     


Lys Ile Phe Ala Arg Ser Glu Asn Leu Lys Ile His Lys Arg Thr His 
            340                 345                 350         


Thr Gly Glu Lys Pro Phe Lys Cys Glu Phe Glu Gly Cys Asp Arg Arg 
        355                 360                 365             


Phe Ala Asn Ser Ser Asp Arg Lys Lys His Met His Val His Thr Ser 
    370                 375                 380                 


Asp Lys Pro Tyr Ile Cys Lys Val Cys Asp Lys Ser Tyr Thr His Pro 
385                 390                 395                 400 


Ser Ser Leu Arg Lys His Met Lys Val His Glu Ser Gln Gly Ser Asp 
                405                 410                 415     


Ser Ser Pro Ala Ala Ser Ser Gly Tyr Glu Ser Ser Thr Pro Pro Ala 
            420                 425                 430         


Ile Ala Ser Ala Asn Ser Lys Asp Thr Thr Lys Thr Pro Ser Ala Val 
        435                 440                 445             


Gln Thr Ser Thr Ser His Asn Pro Gly Leu Pro Pro Asn Phe Asn Glu 
    450                 455                 460                 


Trp Tyr Val 
465         


<210>  3266
<211>  892
<212>  PRT
<213>  homo sapiens

<400>  3266

Met Phe Cys Ala Ala Val Leu Glu Asn Leu Gly Gln Thr Ile Val Pro 
1               5                   10                  15      


Asp Leu Gly Ser Leu Glu Ser Gln His Asp Phe Arg Thr Pro Glu Phe 
            20                  25                  30          


Glu Glu Phe Asn Gly Lys Pro Asp Ser Leu Phe Phe Asn Asp Gly Gln 
        35                  40                  45              


Arg Arg Ile Asp Phe Val Leu Val Tyr Glu Asp Glu Ser Arg Lys Glu 
    50                  55                  60                  


Thr Asn Lys Lys Gly Thr Asn Glu Lys Gln Arg Arg Lys Arg Gln Ala 
65                  70                  75                  80  


Tyr Glu Ser Asn Leu Ile Cys His Gly Leu Gln Leu Glu Ala Thr Arg 
                85                  90                  95      


Ser Val Leu Asp Asp Lys Leu Val Phe Val Lys Val His Ala Pro Trp 
            100                 105                 110         


Glu Val Leu Cys Thr Tyr Ala Glu Ile Met His Ile Lys Leu Pro Leu 
        115                 120                 125             


Lys Pro Asn Asp Leu Lys Asn Arg Ser Ser Ala Phe Gly Thr Leu Asn 
    130                 135                 140                 


Trp Phe Thr Lys Val Leu Ser Val Asp Glu Ser Ile Ile Lys Pro Glu 
145                 150                 155                 160 


Gln Glu Phe Phe Thr Ala Pro Phe Glu Lys Asn Arg Met Asn Asp Phe 
                165                 170                 175     


Tyr Ile Val Asp Arg Asp Ala Phe Phe Asn Pro Ala Thr Arg Ser Arg 
            180                 185                 190         


Ile Val Tyr Phe Ile Leu Ser Arg Val Lys Tyr Gln Val Ile Asn Asn 
        195                 200                 205             


Val Ser Lys Phe Gly Ile Asn Arg Leu Val Asn Ser Gly Ile Tyr Lys 
    210                 215                 220                 


Ala Ala Phe Pro Leu His Asp Cys Lys Phe Arg Arg Gln Ser Glu Asp 
225                 230                 235                 240 


Pro Ser Cys Pro Asn Glu Arg Tyr Leu Leu Tyr Arg Glu Trp Ala His 
                245                 250                 255     


Pro Arg Ser Ile Tyr Lys Lys Gln Pro Leu Asp Leu Ile Arg Lys Tyr 
            260                 265                 270         


Tyr Gly Glu Lys Ile Gly Ile Tyr Phe Ala Trp Leu Gly Tyr Tyr Thr 
        275                 280                 285             


Gln Met Leu Leu Leu Ala Ala Val Val Gly Val Ala Cys Phe Leu Tyr 
    290                 295                 300                 


Gly Tyr Leu Asn Gln Asp Asn Cys Thr Trp Ser Lys Glu Val Cys His 
305                 310                 315                 320 


Pro Asp Ile Gly Gly Lys Ile Ile Met Cys Pro Gln Cys Asp Arg Leu 
                325                 330                 335     


Cys Pro Phe Trp Lys Leu Asn Ile Thr Cys Glu Ser Ser Lys Lys Leu 
            340                 345                 350         


Cys Ile Phe Asp Ser Phe Gly Thr Leu Val Phe Ala Val Phe Met Gly 
        355                 360                 365             


Val Trp Val Thr Leu Phe Leu Glu Phe Trp Lys Arg Arg Gln Ala Glu 
    370                 375                 380                 


Leu Glu Tyr Glu Trp Asp Thr Val Glu Leu Gln Gln Glu Glu Gln Ala 
385                 390                 395                 400 


Arg Pro Glu Tyr Glu Ala Arg Cys Thr His Val Val Ile Asn Glu Ile 
                405                 410                 415     


Thr Gln Glu Glu Glu Arg Ile Pro Phe Thr Ala Trp Gly Lys Cys Ile 
            420                 425                 430         


Arg Ile Thr Leu Cys Ala Ser Ala Val Phe Phe Trp Ile Leu Leu Ile 
        435                 440                 445             


Ile Ala Ser Val Ile Gly Ile Ile Val Tyr Arg Leu Ser Val Phe Ile 
    450                 455                 460                 


Val Phe Ser Ala Lys Leu Pro Lys Asn Ile Asn Gly Thr Asp Pro Ile 
465                 470                 475                 480 


Gln Lys Tyr Leu Thr Pro Gln Thr Ala Thr Ser Ile Thr Ala Ser Ile 
                485                 490                 495     


Ile Ser Phe Ile Ile Ile Met Ile Leu Asn Thr Ile Tyr Glu Lys Val 
            500                 505                 510         


Ala Ile Met Ile Thr Asn Phe Glu Leu Pro Arg Thr Gln Thr Asp Tyr 
        515                 520                 525             


Glu Asn Ser Leu Thr Met Lys Met Phe Leu Phe Gln Phe Val Asn Tyr 
    530                 535                 540                 


Tyr Ser Ser Cys Phe Tyr Ile Ala Phe Phe Lys Gly Lys Phe Val Gly 
545                 550                 555                 560 


Tyr Pro Gly Asp Pro Val Tyr Trp Leu Gly Lys Tyr Arg Asn Glu Glu 
                565                 570                 575     


Cys Asp Pro Gly Gly Cys Leu Leu Glu Leu Thr Thr Gln Leu Thr Ile 
            580                 585                 590         


Ile Met Gly Gly Lys Ala Ile Trp Asn Asn Ile Gln Glu Val Leu Leu 
        595                 600                 605             


Pro Trp Ile Met Asn Leu Ile Gly Arg Phe His Arg Val Ser Gly Ser 
    610                 615                 620                 


Glu Lys Ile Thr Pro Arg Trp Glu Gln Asp Tyr His Leu Gln Pro Met 
625                 630                 635                 640 


Gly Lys Leu Gly Leu Phe Tyr Glu Tyr Leu Glu Met Ile Ile Gln Phe 
                645                 650                 655     


Gly Phe Val Thr Leu Phe Val Ala Ser Phe Pro Leu Ala Pro Leu Leu 
            660                 665                 670         


Ala Leu Val Asn Asn Ile Leu Glu Ile Arg Val Asp Ala Trp Lys Leu 
        675                 680                 685             


Thr Thr Gln Phe Arg Arg Leu Val Pro Glu Lys Ala Gln Asp Ile Gly 
    690                 695                 700                 


Ala Trp Gln Pro Ile Met Gln Gly Ile Ala Ile Leu Ala Val Val Thr 
705                 710                 715                 720 


Asn Ala Met Ile Ile Ala Phe Thr Ser Asp Met Ile Pro Arg Leu Val 
                725                 730                 735     


Tyr Tyr Trp Ser Phe Ser Val Pro Pro Tyr Gly Asp His Thr Ser Tyr 
            740                 745                 750         


Thr Met Glu Gly Tyr Ile Asn Asn Thr Leu Ser Ile Phe Lys Val Ala 
        755                 760                 765             


Asp Phe Lys Asn Lys Ser Lys Gly Asn Pro Tyr Ser Asp Leu Gly Asn 
    770                 775                 780                 


His Thr Thr Cys Arg Tyr Arg Asp Phe Arg Tyr Pro Pro Gly His Pro 
785                 790                 795                 800 


Gln Glu Tyr Lys His Asn Ile Tyr Tyr Trp His Val Ile Ala Ala Lys 
                805                 810                 815     


Leu Ala Phe Ile Ile Val Met Glu His Val Ile Tyr Ser Val Lys Phe 
            820                 825                 830         


Phe Ile Ser Tyr Ala Ile Pro Asp Val Ser Lys Arg Thr Lys Ser Lys 
        835                 840                 845             


Ile Gln Arg Glu Lys Tyr Leu Thr Gln Lys Leu Leu His Glu Asn His 
    850                 855                 860                 


Leu Lys Asp Met Thr Lys Asn Met Gly Val Ile Ala Glu Arg Met Ile 
865                 870                 875                 880 


Glu Ala Val Asp Asn Asn Leu Arg Pro Lys Ser Glu 
                885                 890         


<210>  3267
<211>  531
<212>  PRT
<213>  homo sapiens

<400>  3267

Met Asp Gly Ile Val Thr Glu Val Ala Val Gly Val Lys Arg Gly Ser 
1               5                   10                  15      


Asp Glu Leu Leu Ser Gly Ser Val Leu Ser Ser Pro Asn Ser Asn Met 
            20                  25                  30          


Ser Ser Met Val Val Thr Ala Asn Gly Asn Asp Ser Lys Lys Phe Lys 
        35                  40                  45              


Gly Glu Asp Lys Met Asp Gly Ala Pro Ser Arg Val Leu His Ile Arg 
    50                  55                  60                  


Lys Leu Pro Gly Glu Val Thr Glu Thr Glu Val Ile Ala Leu Gly Leu 
65                  70                  75                  80  


Pro Phe Gly Lys Val Thr Asn Ile Leu Met Leu Lys Gly Lys Asn Gln 
                85                  90                  95      


Ala Phe Leu Glu Leu Ala Thr Glu Glu Ala Ala Ile Thr Met Val Asn 
            100                 105                 110         


Tyr Tyr Ser Ala Val Thr Pro His Leu Arg Asn Gln Pro Ile Tyr Ile 
        115                 120                 125             


Gln Tyr Ser Asn His Lys Glu Leu Lys Thr Asp Asn Thr Leu Asn Gln 
    130                 135                 140                 


Arg Ala Gln Ala Val Leu Gln Ala Val Thr Ala Val Gln Thr Ala Asn 
145                 150                 155                 160 


Thr Pro Leu Ser Gly Thr Thr Val Ser Glu Ser Ala Val Thr Pro Ala 
                165                 170                 175     


Gln Ser Pro Val Leu Arg Ile Ile Ile Asp Asn Met Tyr Tyr Pro Val 
            180                 185                 190         


Thr Leu Asp Val Leu His Gln Ile Phe Ser Lys Phe Gly Ala Val Leu 
        195                 200                 205             


Lys Ile Ile Thr Phe Thr Lys Asn Asn Gln Phe Gln Ala Leu Leu Gln 
    210                 215                 220                 


Tyr Gly Asp Pro Val Asn Ala Gln Gln Ala Lys Leu Ala Leu Asp Gly 
225                 230                 235                 240 


Gln Asn Ile Tyr Asn Ala Cys Cys Thr Leu Arg Ile Asp Phe Ser Lys 
                245                 250                 255     


Leu Val Asn Leu Asn Val Lys Tyr Asn Asn Asp Lys Ser Arg Asp Tyr 
            260                 265                 270         


Thr Arg Pro Asp Leu Pro Ser Gly Asp Gly Gln Pro Ala Leu Asp Pro 
        275                 280                 285             


Ala Ile Ala Ala Ala Phe Ala Lys Glu Thr Ser Leu Leu Ala Val Pro 
    290                 295                 300                 


Gly Ala Leu Ser Pro Leu Ala Ile Pro Asn Ala Ala Ala Ala Ala Ala 
305                 310                 315                 320 


Ala Ala Ala Ala Gly Arg Val Gly Met Pro Gly Val Ser Ala Gly Gly 
                325                 330                 335     


Asn Thr Val Leu Leu Val Ser Asn Leu Asn Glu Glu Met Val Thr Pro 
            340                 345                 350         


Gln Ser Leu Phe Thr Leu Phe Gly Val Tyr Gly Asp Val Gln Arg Val 
        355                 360                 365             


Lys Ile Leu Tyr Asn Lys Lys Asp Ser Ala Leu Ile Gln Met Ala Asp 
    370                 375                 380                 


Gly Asn Gln Ser Gln Leu Ala Met Asn His Leu Asn Gly Gln Lys Met 
385                 390                 395                 400 


Tyr Gly Lys Ile Ile Arg Val Thr Leu Ser Lys His Gln Thr Val Gln 
                405                 410                 415     


Leu Pro Arg Glu Gly Leu Asp Asp Gln Gly Leu Thr Lys Asp Phe Gly 
            420                 425                 430         


Asn Ser Pro Leu His Arg Phe Lys Lys Pro Gly Ser Lys Asn Phe Gln 
        435                 440                 445             


Asn Ile Phe Pro Pro Ser Ala Thr Leu His Leu Ser Asn Ile Pro Pro 
    450                 455                 460                 


Ser Val Ala Glu Glu Asp Leu Arg Thr Leu Phe Ala Asn Thr Gly Gly 
465                 470                 475                 480 


Thr Val Lys Ala Phe Lys Phe Phe Gln Asp His Lys Met Ala Leu Leu 
                485                 490                 495     


Gln Met Ala Thr Val Glu Glu Ala Ile Gln Ala Leu Ile Asp Leu His 
            500                 505                 510         


Asn Tyr Asn Leu Gly Glu Asn His His Leu Arg Val Ser Phe Ser Lys 
        515                 520                 525             


Ser Thr Ile 
    530     


<210>  3268
<211>  301
<212>  PRT
<213>  homo sapiens

<400>  3268

Met Val Arg Thr Lys Thr Trp Thr Leu Lys Lys His Phe Val Gly Tyr 
1               5                   10                  15      


Pro Thr Asn Ser Asp Phe Glu Leu Lys Thr Ala Glu Leu Pro Pro Leu 
            20                  25                  30          


Lys Asn Gly Glu Val Leu Leu Glu Ala Leu Phe Leu Thr Val Asp Pro 
        35                  40                  45              


Tyr Met Arg Val Ala Ala Lys Arg Leu Lys Glu Gly Asp Thr Met Met 
    50                  55                  60                  


Gly Gln Gln Val Ala Lys Val Val Glu Ser Lys Asn Val Ala Leu Pro 
65                  70                  75                  80  


Lys Gly Thr Ile Val Leu Ala Ser Pro Gly Trp Thr Thr His Ser Ile 
                85                  90                  95      


Ser Asp Gly Lys Asp Leu Glu Lys Leu Leu Thr Glu Trp Pro Asp Thr 
            100                 105                 110         


Ile Pro Leu Ser Leu Ala Leu Gly Thr Val Gly Met Pro Gly Leu Thr 
        115                 120                 125             


Ala Tyr Phe Gly Leu Leu Glu Ile Cys Gly Val Lys Gly Gly Glu Thr 
    130                 135                 140                 


Val Met Val Asn Ala Ala Ala Gly Ala Val Gly Ser Val Val Gly Gln 
145                 150                 155                 160 


Ile Ala Lys Leu Lys Gly Cys Lys Val Val Gly Ala Val Gly Ser Asp 
                165                 170                 175     


Glu Lys Val Ala Tyr Leu Gln Lys Leu Gly Phe Asp Val Val Phe Asn 
            180                 185                 190         


Tyr Lys Thr Val Glu Ser Leu Glu Glu Thr Leu Lys Lys Ala Ser Pro 
        195                 200                 205             


Asp Gly Tyr Asp Cys Tyr Phe Asp Asn Val Gly Gly Glu Phe Ser Asn 
    210                 215                 220                 


Thr Val Ile Gly Gln Met Lys Lys Phe Gly Arg Ile Ala Ile Cys Gly 
225                 230                 235                 240 


Ala Ile Ser Thr Tyr Asn Arg Thr Gly Pro Leu Pro Pro Gly Pro Pro 
                245                 250                 255     


Pro Glu Ile Val Ile Tyr Gln Glu Leu Arg Met Glu Ala Phe Val Val 
            260                 265                 270         


Tyr Arg Trp Gln Gly Asp Ala Arg Gln Lys Ala Leu Lys Asp Leu Leu 
        275                 280                 285             


Lys Trp Val Leu Glu Ile Lys Arg Glu Asn Glu Glu Asp 
    290                 295                 300     


<210>  3269
<211>  472
<212>  PRT
<213>  homo sapiens

<400>  3269

Met Asn Gly Tyr Gly Ser Pro Tyr Leu Tyr Met Gly Gly Pro Val Ser 
1               5                   10                  15      


Gln Pro Pro Arg Ala Pro Leu Gln Arg Thr Pro Lys Cys Ala Arg Cys 
            20                  25                  30          


Arg Asn His Gly Val Leu Ser Trp Leu Lys Gly His Lys Arg Tyr Cys 
        35                  40                  45              


Arg Phe Lys Asp Cys Thr Cys Glu Lys Cys Ile Leu Ile Ile Glu Arg 
    50                  55                  60                  


Gln Arg Val Met Ala Ala Gln Val Ala Leu Arg Arg Gln Gln Ala Asn 
65                  70                  75                  80  


Glu Ser Leu Glu Ser Leu Ile Pro Asp Ser Leu Arg Ala Leu Pro Gly 
                85                  90                  95      


Pro Pro Pro Pro Gly Asp Ala Val Ala Ala Pro Gln Pro Pro Pro Ala 
            100                 105                 110         


Ser Gln Pro Ser Gln Pro Gln Pro Pro Arg Pro Ala Ala Glu Leu Ala 
        115                 120                 125             


Ala Ala Ala Ala Leu Arg Trp Thr Ala Glu Pro Gln Pro Gly Ala Leu 
    130                 135                 140                 


Gln Ala Gln Leu Ala Lys Pro Asp Leu Thr Glu Glu Arg Leu Gly Asp 
145                 150                 155                 160 


Gly Lys Ser Ala Asp Asn Thr Glu Val Phe Ser Asp Lys Asp Thr Asp 
                165                 170                 175     


Gln Arg Ser Ser Pro Asp Val Ala Lys Ser Lys Gly Cys Phe Thr Pro 
            180                 185                 190         


Glu Ser Pro Glu Ile Val Ser Val Glu Glu Gly Gly Tyr Ala Val Gln 
        195                 200                 205             


Lys Asn Gly Gly Asn Pro Glu Ser Arg Pro Asp Ser Pro Lys Cys His 
    210                 215                 220                 


Ala Glu Gln Asn His Leu Leu Ile Glu Gly Pro Ser Gly Thr Val Ser 
225                 230                 235                 240 


Leu Pro Phe Ser Leu Lys Ala Asn Arg Pro Pro Leu Glu Val Leu Lys 
                245                 250                 255     


Lys Ile Phe Pro Asn Gln Lys Pro Thr Val Leu Glu Leu Ile Leu Lys 
            260                 265                 270         


Gly Cys Gly Gly Asp Leu Val Ser Ala Val Glu Val Leu Leu Ser Ser 
        275                 280                 285             


Arg Ser Ser Val Thr Gly Ala Glu Arg Thr Ser Ala Glu Pro Glu Ser 
    290                 295                 300                 


Leu Ala Leu Pro Ser Asn Gly His Ile Phe Glu His Thr Leu Ser Ser 
305                 310                 315                 320 


Tyr Pro Ile Ser Ser Ser Lys Trp Ser Val Gly Ser Ala Phe Arg Val 
                325                 330                 335     


Pro Asp Thr Leu Arg Phe Ser Ala Asp Ser Ser Asn Val Val Pro Ser 
            340                 345                 350         


Pro Leu Ala Gly Pro Leu Gln Pro Pro Phe Pro Gln Pro Pro Arg Tyr 
        355                 360                 365             


Pro Leu Met Leu Arg Asn Thr Leu Ala Arg Ser Gln Ser Ser Pro Phe 
    370                 375                 380                 


Leu Pro Asn Asp Val Thr Leu Trp Asn Thr Met Thr Leu Gln Gln Gln 
385                 390                 395                 400 


Tyr Gln Leu Arg Ser Gln Tyr Val Ser Pro Phe Pro Ser Asn Ser Thr 
                405                 410                 415     


Ser Val Phe Arg Ser Ser Pro Val Leu Pro Ala Arg Ala Thr Glu Asp 
            420                 425                 430         


Pro Arg Ile Ser Ile Pro Asp Asp Gly Cys Pro Phe Val Ser Lys Gln 
        435                 440                 445             


Ser Ile Tyr Thr Glu Asp Asp Tyr Asp Glu Arg Ser Asp Ser Ser Asp 
    450                 455                 460                 


Ser Arg Thr Leu Asn Thr Ser Ser 
465                 470         


<210>  3270
<211>  261
<212>  PRT
<213>  homo sapiens

<400>  3270

Met Ala Glu Ser His Leu Gln Ser Ser Leu Ile Thr Ala Ser Gln Phe 
1               5                   10                  15      


Phe Glu Ile Trp Leu His Phe Asp Ala Asp Gly Ser Gly Tyr Leu Glu 
            20                  25                  30          


Gly Lys Glu Leu Gln Asn Leu Ile Gln Glu Leu Gln Gln Ala Arg Lys 
        35                  40                  45              


Lys Ala Gly Leu Glu Leu Ser Pro Glu Met Lys Thr Phe Val Asp Gln 
    50                  55                  60                  


Tyr Gly Gln Arg Asp Asp Gly Lys Ile Gly Ile Val Glu Leu Ala His 
65                  70                  75                  80  


Val Leu Pro Thr Glu Glu Asn Phe Leu Leu Leu Phe Arg Cys Gln Gln 
                85                  90                  95      


Leu Lys Ser Cys Glu Glu Phe Met Lys Thr Trp Arg Lys Tyr Asp Thr 
            100                 105                 110         


Asp His Ser Gly Phe Ile Glu Thr Glu Glu Leu Lys Asn Phe Leu Lys 
        115                 120                 125             


Asp Leu Leu Glu Lys Ala Asn Lys Thr Val Asp Asp Thr Lys Leu Ala 
    130                 135                 140                 


Glu Tyr Thr Asp Leu Met Leu Lys Leu Phe Asp Ser Asn Asn Asp Gly 
145                 150                 155                 160 


Lys Leu Glu Leu Thr Glu Met Ala Arg Leu Leu Pro Val Gln Glu Asn 
                165                 170                 175     


Phe Leu Leu Lys Phe Gln Gly Ile Lys Met Cys Gly Lys Glu Phe Asn 
            180                 185                 190         


Lys Ala Phe Glu Leu Tyr Asp Gln Asp Gly Asn Gly Tyr Ile Asp Glu 
        195                 200                 205             


Asn Glu Leu Asp Ala Leu Leu Lys Asp Leu Cys Glu Lys Asn Lys Gln 
    210                 215                 220                 


Asp Leu Asp Ile Asn Asn Ile Thr Thr Tyr Lys Lys Asn Ile Met Ala 
225                 230                 235                 240 


Leu Ser Asp Gly Gly Lys Leu Tyr Arg Thr Asp Leu Ala Leu Ile Leu 
                245                 250                 255     


Cys Ala Gly Asp Asn 
            260     


<210>  3271
<211>  441
<212>  PRT
<213>  homo sapiens

<400>  3271

Met Ala Val Val Pro Ala Ser Leu Ser Gly Gln Asp Val Gly Ser Phe 
1               5                   10                  15      


Ala Tyr Leu Thr Ile Lys Asp Arg Ile Pro Gln Ile Leu Thr Lys Val 
            20                  25                  30          


Ile Asp Thr Leu His Arg His Lys Ser Glu Phe Phe Glu Lys His Gly 
        35                  40                  45              


Glu Glu Gly Val Glu Ala Glu Lys Lys Ala Ile Ser Leu Leu Ser Lys 
    50                  55                  60                  


Leu Arg Asn Glu Leu Gln Thr Asp Lys Pro Phe Ile Pro Leu Val Glu 
65                  70                  75                  80  


Lys Phe Val Asp Thr Asp Ile Trp Asn Gln Tyr Leu Glu Tyr Gln Gln 
                85                  90                  95      


Ser Leu Leu Asn Glu Ser Asp Gly Lys Ser Arg Trp Phe Tyr Ser Pro 
            100                 105                 110         


Trp Leu Leu Val Glu Cys Tyr Met Tyr Arg Arg Ile His Glu Ala Ile 
        115                 120                 125             


Ile Gln Ser Pro Pro Ile Asp Tyr Phe Asp Val Phe Lys Glu Ser Lys 
    130                 135                 140                 


Glu Gln Asn Phe Tyr Gly Ser Gln Glu Ser Ile Ile Ala Leu Cys Thr 
145                 150                 155                 160 


His Leu Gln Gln Leu Ile Arg Thr Ile Glu Asp Leu Asp Glu Asn Gln 
                165                 170                 175     


Leu Lys Asp Glu Phe Phe Lys Leu Leu Gln Ile Ser Leu Trp Gly Asn 
            180                 185                 190         


Lys Cys Asp Leu Ser Leu Ser Gly Gly Glu Ser Ser Ser Gln Asn Thr 
        195                 200                 205             


Asn Val Leu Asn Ser Leu Glu Asp Leu Lys Pro Phe Ile Leu Leu Asn 
    210                 215                 220                 


Asp Met Glu His Leu Trp Ser Leu Leu Ser Asn Cys Lys Lys Thr Arg 
225                 230                 235                 240 


Glu Lys Ala Ser Ala Thr Arg Val Tyr Ile Val Leu Asp Asn Ser Gly 
                245                 250                 255     


Phe Glu Leu Val Thr Asp Leu Ile Leu Ala Asp Phe Leu Leu Ser Ser 
            260                 265                 270         


Glu Leu Ala Thr Glu Val His Phe Tyr Gly Lys Thr Ile Pro Trp Phe 
        275                 280                 285             


Val Ser Asp Thr Thr Ile His Asp Phe Asn Trp Leu Ile Glu Gln Val 
    290                 295                 300                 


Lys His Ser Asn His Lys Trp Met Ser Lys Cys Gly Ala Asp Trp Glu 
305                 310                 315                 320 


Glu Tyr Ile Lys Met Gly Lys Trp Val Tyr His Asn His Ile Phe Trp 
                325                 330                 335     


Thr Leu Pro His Glu Tyr Cys Ala Met Pro Gln Val Ala Pro Asp Leu 
            340                 345                 350         


Tyr Ala Glu Leu Gln Lys Ala His Leu Ile Leu Phe Lys Gly Asp Leu 
        355                 360                 365             


Asn Tyr Arg Lys Leu Thr Gly Asp Arg Lys Trp Glu Phe Ser Val Pro 
    370                 375                 380                 


Phe His Gln Ala Leu Asn Gly Phe His Pro Ala Pro Leu Cys Thr Ile 
385                 390                 395                 400 


Arg Thr Leu Lys Ala Glu Ile Gln Val Gly Leu Gln Pro Gly Gln Gly 
                405                 410                 415     


Glu Gln Leu Leu Ala Ser Glu Pro Ser Trp Trp Thr Thr Gly Lys Tyr 
            420                 425                 430         


Gly Ile Phe Gln Tyr Asp Gly Pro Leu 
        435                 440     


<210>  3272
<211>  426
<212>  PRT
<213>  homo sapiens

<400>  3272

Met Val Gly Val Gly Leu Cys Leu Arg Leu Leu Leu Phe Phe Arg Phe 
1               5                   10                  15      


Lys Arg Thr Leu Asp Arg Ile Cys Val Leu Phe Leu Leu Gly Trp His 
            20                  25                  30          


Arg Lys Pro Arg Ser Asp Gly Ser Leu Phe Ile Glu Arg Leu Tyr Ile 
        35                  40                  45              


Gly Ser Ser Lys Thr Phe Thr Ser Ser Glu Lys Ser Leu Thr Pro Leu 
    50                  55                  60                  


Gln Trp Cys Arg His Val Leu Asp Asn Pro Thr Pro Glu Met Glu Ala 
65                  70                  75                  80  


Ala Arg Arg Ser Leu Cys Phe Arg Leu Glu Gln Gly Tyr Thr Ser Arg 
                85                  90                  95      


Gly Ser Pro Leu Ser Pro Gln Ser Ser Ile Asp Ser Glu Leu Ser Thr 
            100                 105                 110         


Ser Glu Leu Glu Asp Asp Ser Ile Ser Met Gly Tyr Lys Leu Gln Asp 
        115                 120                 125             


Leu Thr Asp Val Gln Ile Met Ala Arg Leu Gln Glu Glu Ser Leu Arg 
    130                 135                 140                 


Gln Asp Tyr Ala Ser Thr Ser Ala Ser Val Ser Arg His Ser Ser Ser 
145                 150                 155                 160 


Val Ser Leu Ser Ser Gly Lys Lys Gly Thr Cys Ser Asp Gln Glu Tyr 
                165                 170                 175     


Asp Gln Tyr Ser Leu Glu Asp Glu Glu Glu Phe Asp His Leu Pro Pro 
            180                 185                 190         


Pro Gln Pro Arg Leu Pro Arg Cys Ser Pro Phe Gln Arg Gly Ile Pro 
        195                 200                 205             


His Ser Gln Thr Phe Ser Ser Ile Arg Glu Cys Arg Arg Ser Pro Ser 
    210                 215                 220                 


Ser Gln Tyr Phe Pro Ser Asn Asn Tyr Gln Gln Gln Gln Tyr Tyr Ser 
225                 230                 235                 240 


Pro Gln Ala Gln Thr Pro Asp Gln Gln Pro Asn Arg Thr Asn Gly Asp 
                245                 250                 255     


Lys Leu Arg Arg Ser Met Pro Asn Leu Ala Arg Met Pro Ser Thr Thr 
            260                 265                 270         


Ala Ile Ser Ser Asn Ile Ser Ser Pro Val Thr Val Arg Asn Ser Gln 
        275                 280                 285             


Ser Phe Asp Ser Ser Leu His Gly Ala Gly Asn Gly Ile Ser Arg Ile 
    290                 295                 300                 


Gln Ser Cys Ile Pro Ser Pro Gly Gln Leu Gln His Arg Val His Ser 
305                 310                 315                 320 


Val Gly His Phe Pro Val Ser Ile Arg Gln Pro Leu Lys Ala Thr Ala 
                325                 330                 335     


Tyr Val Ser Pro Thr Val Gln Gly Ser Ser Asn Met Pro Leu Ser Asn 
            340                 345                 350         


Gly Leu Gln Leu Tyr Ser Asn Thr Gly Ile Pro Thr Pro Asn Lys Ala 
        355                 360                 365             


Ala Ala Ser Gly Ile Met Gly Arg Ser Ala Leu Pro Arg Pro Ser Leu 
    370                 375                 380                 


Ala Ile Asn Gly Ser Asn Leu Pro Arg Ser Lys Ile Ala Gln Pro Val 
385                 390                 395                 400 


Arg Ser Phe Leu Gln Pro Pro Lys Pro Leu Ser Ser Leu Ser Thr Leu 
                405                 410                 415     


Arg Asp Gly Asn Trp Arg Asp Gly Cys Tyr 
            420                 425     


<210>  3273
<211>  437
<212>  PRT
<213>  homo sapiens

<400>  3273

Met Asp Gly Asn Asp Asn Val Thr Leu Leu Phe Ala Pro Leu Leu Arg 
1               5                   10                  15      


Asp Asn Tyr Thr Leu Ala Pro Asn Ala Ser Ser Leu Gly Pro Gly Thr 
            20                  25                  30          


Asp Leu Ala Leu Ala Pro Ala Ser Ser Ala Gly Pro Gly Pro Gly Leu 
        35                  40                  45              


Ser Leu Gly Pro Gly Pro Ser Phe Gly Phe Ser Pro Gly Pro Thr Pro 
    50                  55                  60                  


Thr Pro Glu Pro Thr Thr Ser Gly Leu Ala Gly Gly Ala Ala Ser His 
65                  70                  75                  80  


Gly Pro Ser Pro Phe Pro Arg Pro Trp Ala Pro His Ala Leu Pro Phe 
                85                  90                  95      


Trp Asp Thr Pro Leu Asn His Gly Leu Asn Val Phe Val Gly Ala Ala 
            100                 105                 110         


Leu Cys Ile Thr Met Leu Gly Leu Gly Cys Thr Val Asp Val Asn His 
        115                 120                 125             


Phe Gly Ala His Val Arg Arg Pro Val Gly Ala Leu Leu Ala Ala Leu 
    130                 135                 140                 


Cys Gln Phe Gly Leu Leu Pro Leu Leu Ala Phe Leu Leu Ala Leu Ala 
145                 150                 155                 160 


Phe Lys Leu Asp Glu Val Ala Ala Val Ala Val Leu Leu Cys Gly Cys 
                165                 170                 175     


Cys Pro Gly Gly Asn Leu Ser Asn Leu Met Ser Leu Leu Val Asp Gly 
            180                 185                 190         


Asp Met Asn Leu Ser Ile Ile Met Thr Ile Ser Ser Thr Leu Leu Ala 
        195                 200                 205             


Leu Val Leu Met Pro Leu Cys Leu Trp Ile Tyr Ser Trp Ala Trp Ile 
    210                 215                 220                 


Asn Thr Pro Ile Val Gln Leu Leu Pro Leu Gly Thr Val Thr Leu Thr 
225                 230                 235                 240 


Leu Cys Ser Thr Leu Ile Pro Ile Gly Leu Gly Val Phe Ile Arg Tyr 
                245                 250                 255     


Lys Tyr Ser Arg Val Ala Asp Tyr Ile Val Lys Val Ser Leu Trp Ser 
            260                 265                 270         


Leu Leu Val Thr Leu Val Val Leu Phe Ile Met Thr Gly Thr Met Leu 
        275                 280                 285             


Gly Pro Glu Leu Leu Ala Ser Ile Pro Ala Ala Val Tyr Val Ile Ala 
    290                 295                 300                 


Ile Phe Met Pro Leu Ala Gly Tyr Ala Ser Gly Tyr Gly Leu Ala Thr 
305                 310                 315                 320 


Leu Phe His Leu Pro Pro Asn Cys Lys Arg Thr Val Cys Leu Glu Thr 
                325                 330                 335     


Gly Ser Gln Asn Val Gln Leu Cys Thr Ala Ile Leu Lys Leu Ala Phe 
            340                 345                 350         


Pro Pro Gln Phe Ile Gly Ser Met Tyr Met Phe Pro Leu Leu Tyr Ala 
        355                 360                 365             


Leu Phe Gln Ser Ala Glu Ala Gly Ile Phe Val Leu Ile Tyr Lys Met 
    370                 375                 380                 


Tyr Gly Ser Glu Met Leu His Lys Arg Asp Pro Leu Asp Glu Asp Glu 
385                 390                 395                 400 


Asp Thr Asp Ile Ser Tyr Lys Lys Leu Lys Glu Glu Glu Met Ala Asp 
                405                 410                 415     


Thr Ser Tyr Gly Thr Val Lys Ala Glu Asn Ile Ile Met Met Glu Thr 
            420                 425                 430         


Ala Gln Thr Ser Leu 
        435         


<210>  3274
<211>  384
<212>  PRT
<213>  homo sapiens

<400>  3274

Met Pro Pro Phe Cys Arg Asn Ala Lys Leu Gly Leu Leu Ser Phe Leu 
1               5                   10                  15      


Ile Cys Ala Gly Arg Ser Leu Leu Pro Leu Gly Lys Asn Ala Phe Trp 
            20                  25                  30          


Leu Glu Arg Ile Glu Asn Asn Asn Thr Leu Trp Glu Lys Ala Gln Ser 
        35                  40                  45              


Gln Lys Met Arg Tyr Lys Thr Ser Leu Val Met Arg Lys Arg Leu Arg 
    50                  55                  60                  


Leu Tyr Arg Asn Thr Leu Lys Glu Ser Ser Ser Ser Ser Gly His His 
65                  70                  75                  80  


Gly Pro Gln Leu Thr Ala Ala Ser Ser Pro Ser Val Phe Pro Gly Leu 
                85                  90                  95      


His Glu Glu Pro Pro Gln Ala Ser Pro Ser Arg Pro Leu Asn Gly Leu 
            100                 105                 110         


Leu Arg Leu Gly Leu Pro Gly Asp Met Tyr Ala Arg Pro Glu Pro Phe 
        115                 120                 125             


Pro Pro Gly Pro Ala Ala Arg Ser Asp Ala Leu Ala Ala Ala Ala Ala 
    130                 135                 140                 


Leu His Gly Tyr Gly Gly Met Asn Leu Thr Val Asn Leu Ala Ala Pro 
145                 150                 155                 160 


His Gly Pro Gly Ala Phe Phe Arg Tyr Met Arg Gln Pro Ile Lys Gln 
                165                 170                 175     


Glu Leu Ile Cys Lys Trp Leu Ala Ala Asp Gly Thr Ala Thr Pro Ser 
            180                 185                 190         


Leu Cys Ser Lys Thr Phe Ser Thr Met His Glu Leu Val Thr His Val 
        195                 200                 205             


Thr Val Glu His Val Gly Gly Pro Glu Gln Ala Asn His Ile Cys Phe 
    210                 215                 220                 


Trp Glu Glu Cys Pro Arg Gln Gly Lys Pro Phe Lys Ala Lys Tyr Lys 
225                 230                 235                 240 


Leu Val Asn His Ile Arg Val His Thr Gly Glu Lys Pro Phe Pro Cys 
                245                 250                 255     


Pro Phe Pro Gly Cys Gly Lys Val Phe Ala Arg Ser Glu Asn Leu Lys 
            260                 265                 270         


Ile His Lys Arg Thr His Thr Gly Glu Lys Pro Phe Arg Cys Glu Phe 
        275                 280                 285             


Glu Gly Cys Glu Arg Arg Phe Ala Asn Ser Ser Asp Arg Lys Lys His 
    290                 295                 300                 


Ser His Val His Thr Ser Asp Lys Pro Tyr Thr Cys Lys Val Arg Gly 
305                 310                 315                 320 


Cys Asp Lys Cys Tyr Thr His Pro Ser Ser Leu Arg Lys His Met Lys 
                325                 330                 335     


Val His Gly Arg Ser Pro Pro Pro Ser Ser Gly Tyr Asp Ser Ala Thr 
            340                 345                 350         


Pro Ser Ala Leu Val Ser Pro Ser Ser Asp Cys Gly His Lys Ser Gln 
        355                 360                 365             


Val Ala Ser Ser Ala Ala Val Ala Ala Arg Thr Ala Asp Leu Ser Glu 
    370                 375                 380                 


<210>  3275
<211>  1059
<212>  PRT
<213>  homo sapiens

<400>  3275

Met Ser Gly Val Met Val Gly Ser His Ala Asp Met Ala Pro Ala Ser 
1               5                   10                  15      


Thr Ala Glu Gly Ala Gly Glu Lys Pro Gly Pro Ala Ala Pro Ala Pro 
            20                  25                  30          


Ala Ala Gln Tyr Glu Cys Gly Glu Cys Gly Lys Ser Phe Arg Trp Ser 
        35                  40                  45              


Ser Arg Leu Leu His His Gln Arg Thr His Thr Gly Glu Arg Pro Tyr 
    50                  55                  60                  


Lys Cys Pro Asp Cys Pro Lys Ala Phe Lys Gly Ser Ser Ala Leu Leu 
65                  70                  75                  80  


Tyr His Gln Arg Gly His Thr Gly Glu Arg Pro Tyr Gln Cys Pro Asp 
                85                  90                  95      


Cys Pro Lys Ala Phe Lys Arg Ser Ser Leu Leu Gln Ile His Arg Ser 
            100                 105                 110         


Val His Thr Gly Leu Arg Ala Phe Ile Cys Gly Gln Cys Gly Leu Ala 
        115                 120                 125             


Phe Lys Trp Ser Ser His Tyr Gln Tyr His Leu Arg Gln His Thr Gly 
    130                 135                 140                 


Glu Arg Pro Tyr Pro Cys Pro Asp Cys Pro Lys Ala Phe Lys Asn Ser 
145                 150                 155                 160 


Ser Ser Leu Arg Arg His Arg His Val His Thr Gly Glu Arg Pro Tyr 
                165                 170                 175     


Thr Cys Gly Val Cys Gly Lys Ser Phe Thr Gln Ser Thr Asn Leu Arg 
            180                 185                 190         


Gln His Gln Arg Val His Thr Gly Glu Arg Pro Phe Arg Cys Pro Leu 
        195                 200                 205             


Cys Pro Lys Thr Phe Thr His Ser Ser Asn Leu Leu Leu His Gln Arg 
    210                 215                 220                 


Thr His Gly Ala Ala Pro Ala Pro Gly Thr Ala Ser Ala Ala Pro Pro 
225                 230                 235                 240 


Pro Gln Ser Arg Glu Pro Gly Lys Val Phe Val Cys Asp Ala Tyr Leu 
                245                 250                 255     


Gln Arg His Leu Gln Pro His Ser Pro Pro Ala Pro Pro Ala Pro Pro 
            260                 265                 270         


Pro Pro Pro Pro Pro Val Val Pro Glu Leu Phe Leu Ala Ala Ala Glu 
        275                 280                 285             


Thr Thr Val Glu Leu Val Tyr Arg Cys Asp Gly Cys Glu Gln Gly Phe 
    290                 295                 300                 


Ser Ser Glu Glu Leu Leu Leu Glu His Gln Pro Cys Pro Gly Pro Asp 
305                 310                 315                 320 


Ala Ala Pro Gln Pro Gln Glu Ala Pro Ala Glu Ala Pro Lys Ala Asp 
                325                 330                 335     


Gln Pro Pro Ser Pro Leu Pro Gln Pro Pro Pro Pro Ala Ala Ala Pro 
            340                 345                 350         


Ala Pro Gly Phe Ala Cys Leu Pro Cys Gly Lys Ser Phe Arg Thr Val 
        355                 360                 365             


Ala Gly Leu Ser Arg His Gln His Ser His Gly Ala Ala Gly Gly Gln 
    370                 375                 380                 


Ala Phe Arg Cys Gly Ser Cys Asp Gly Ser Phe Pro Gln Leu Ala Ser 
385                 390                 395                 400 


Leu Leu Ala His Gln Gln Cys His Val Glu Glu Ala Ala Ala Gly Arg 
                405                 410                 415     


Pro Pro Pro Gln Ala Glu Ala Ala Glu Val Thr Cys Pro Gln Glu Pro 
            420                 425                 430         


Leu Ala Pro Ala Ala Pro Val Pro Pro Pro Pro Pro Ser Ala Pro Ala 
        435                 440                 445             


Ser Ala Glu Arg Pro Tyr Lys Cys Ala Glu Cys Gly Lys Ser Phe Lys 
    450                 455                 460                 


Gly Ser Ser Gly Leu Arg Tyr His Leu Arg Asp His Thr Gly Glu Arg 
465                 470                 475                 480 


Pro Tyr Gln Cys Gly Glu Cys Gly Lys Ala Phe Lys Arg Ser Ser Leu 
                485                 490                 495     


Leu Ala Ile His Gln Arg Val His Thr Gly Leu Arg Ala Phe Thr Cys 
            500                 505                 510         


Gly Gln Cys Gly Leu Thr Phe Lys Trp Ser Ser His Tyr Gln Tyr His 
        515                 520                 525             


Leu Arg Leu His Ser Gly Glu Arg Pro Tyr Ala Cys Gly Glu Cys Gly 
    530                 535                 540                 


Lys Ala Phe Arg Asn Thr Ser Cys Leu Arg Arg His Arg His Val His 
545                 550                 555                 560 


Thr Gly Glu Arg Pro His Ala Cys Gly Val Cys Gly Lys Ser Phe Ala 
                565                 570                 575     


Gln Thr Ser Asn Leu Arg Gln His Gln Arg Val His Thr Gly Glu Arg 
            580                 585                 590         


Pro Phe Arg Cys Pro Leu Cys Pro Lys Thr Phe Thr His Ser Ser Asn 
        595                 600                 605             


Leu Leu Leu His Gln Arg Thr His Ser Ala Glu Arg Pro Phe Thr Cys 
    610                 615                 620                 


Pro Ile Cys Gly Arg Gly Phe Val Met Ala Ala Tyr Leu Gln Arg His 
625                 630                 635                 640 


Leu Arg Thr His Ala Pro Ala Asn Thr Pro Pro Ser Thr Thr Ala Pro 
                645                 650                 655     


Ala Ala Gly Pro Gln Pro Pro Ala Pro Leu Ala Ala Ala Arg Ala Pro 
            660                 665                 670         


Pro Ala Thr Gln Asp Val His Val Leu Pro His Leu Gln Ala Thr Leu 
        675                 680                 685             


Ser Leu Glu Val Ala Gly Gly Thr Ala Gln Ala Pro Ser Leu Gly Pro 
    690                 695                 700                 


Ala Ala Pro Asn Ser Gln Thr Phe Leu Leu Val Gln Thr Ala Gln Gly 
705                 710                 715                 720 


Leu Gln Leu Ile Pro Ser Ser Val Gln Pro Pro Thr Pro Pro Pro Pro 
                725                 730                 735     


Pro Ala Pro Pro Lys Leu Ile Leu Leu Pro Ser Ser Ser Ala Gly Ala 
            740                 745                 750         


Gly Gly Gly Arg Ala Arg Gln Gly Pro Arg Ala Val Gly Lys Ala Gly 
        755                 760                 765             


Gln Gly Ala Gly Val Val Trp Leu Pro Gly Pro Gly Gly Leu Gly Val 
    770                 775                 780                 


Gln Gly Ala Ala Ser Ala Gly Ala Ser Gly Thr Gly Gln Ser Leu Ile 
785                 790                 795                 800 


Val Leu Gln Asn Val Gly Gly Gly Glu Ala Gly Pro Gln Glu Met Ser 
                805                 810                 815     


Gly Val Gln Leu Gln Pro Leu Arg Pro Ala Pro Glu Val Thr Thr Val 
            820                 825                 830         


Gln Leu Gln Pro Ala Gln Glu Val Thr Thr Val Gln Leu Gln Pro Ala 
        835                 840                 845             


Gln Glu Val Thr Thr Val Gln Leu Gln Pro Ala Gln Glu Val Thr Thr 
    850                 855                 860                 


Val Gln Leu Gln Pro Val Ala Gly Gln Leu Ser Asn Ser Ser Gly Gly 
865                 870                 875                 880 


Ala Val Ala Thr Glu Ala Pro Asn Leu Leu Val Val Gln Ser Gly Ala 
                885                 890                 895     


Ala Glu Glu Leu Leu Thr Gly Pro Gly Pro Gly Glu Ala Gly Asp Gly 
            900                 905                 910         


Glu Ala Ser Thr Gly Val Val Gln Asp Val Leu Phe Glu Thr Leu Gln 
        915                 920                 925             


Thr Asp Glu Gly Leu Gln Ser Val Leu Val Leu Ser Gly Ala Asp Gly 
    930                 935                 940                 


Glu Gln Thr Arg Leu Cys Val Gln Glu Val Glu Thr Leu Pro Pro Gly 
945                 950                 955                 960 


Leu Thr Glu Pro Pro Ala Thr Gly Pro Pro Gly Gln Lys Leu Leu Ile 
                965                 970                 975     


Ile Arg Ser Ala Pro Ala Thr Glu Leu Leu Asp Ser Ser Asn Thr Gly 
            980                 985                 990         


Gly Gly Thr Ala Thr Leu Gln Leu  Leu Ala Pro Pro Pro  Ser Gly Pro 
        995                 1000                 1005             


Ala Ser  Gly Pro Ala Gly Leu  Pro Gly Ala Pro Ala  Ser Gln Met 
    1010                 1015                 1020             


Val Gln  Val Val Pro Ala Gly  Ala Gly Pro Gly Val  Met Thr Pro 
    1025                 1030                 1035             


Gln Gly  Leu Pro Ser Ile Gln  Ile Val Gln Thr Leu  Pro Ala Val 
    1040                 1045                 1050             


Gln Leu  Val His Thr Phe 
    1055                 


<210>  3276
<211>  606
<212>  PRT
<213>  homo sapiens

<400>  3276

Met Ser His Thr Ala Ser Ser Cys Gln Glu Leu Val Glu Asn Cys Ala 
1               5                   10                  15      


Val His Val Ala Gly Met Ala Gln Glu Asp Ser Arg Arg Gly Gln Val 
            20                  25                  30          


Pro Ser Ser Phe Tyr His Gly Ala Asn Gln Glu Leu Asp Leu Ser Thr 
        35                  40                  45              


Lys Val Tyr Lys Arg Glu Ser Gly Ser Pro Tyr Ser Val Leu Val Asp 
    50                  55                  60                  


Thr Lys Met Ser Lys Pro His Leu His Glu Thr Glu Glu Gln Pro Tyr 
65                  70                  75                  80  


Phe Arg Glu Thr Arg Ala Val Ser Asp Val His Ala Val Lys Glu Asp 
                85                  90                  95      


Arg Glu Asn Ser Asp Asp Thr Glu Glu Glu Glu Glu Glu Val Ser Tyr 
            100                 105                 110         


Lys Arg Glu Gln Ile Ile Val Glu Val Asn Leu Asn Asn Gln Thr Leu 
        115                 120                 125             


Asn Val Ser Lys Gly Glu Lys Gly Val Ser Ser Gln Ser Lys Glu Thr 
    130                 135                 140                 


Pro Val Leu Lys Thr Ser Ser Glu Glu Glu Glu Glu Glu Ser Glu Glu 
145                 150                 155                 160 


Glu Ala Thr Asp Asp Ser Asn Asp Tyr Gly Glu Asn Glu Lys Gln Lys 
                165                 170                 175     


Lys Lys Glu Lys Ile Val Glu Lys Val Ser Val Thr Gln Arg Arg Thr 
            180                 185                 190         


Arg Arg Ala Ala Ser Val Ala Ala Ala Thr Thr Ser Pro Thr Pro Arg 
        195                 200                 205             


Thr Thr Arg Gly Arg Arg Lys Ser Val Glu Pro Pro Lys Arg Lys Lys 
    210                 215                 220                 


Arg Ala Thr Lys Glu Pro Lys Ala Pro Val Gln Lys Ala Lys Cys Glu 
225                 230                 235                 240 


Glu Lys Glu Thr Leu Thr Cys Glu Lys Cys Pro Arg Val Phe Asn Thr 
                245                 250                 255     


Arg Trp Tyr Leu Glu Lys His Met Asn Val Thr His Arg Arg Met Gln 
            260                 265                 270         


Ile Cys Asp Lys Cys Gly Lys Lys Phe Val Leu Glu Ser Glu Leu Ser 
        275                 280                 285             


Leu His Gln Gln Thr Asp Cys Glu Lys Asn Ile Gln Cys Val Ser Cys 
    290                 295                 300                 


Asn Lys Ser Phe Lys Lys Leu Trp Ser Leu His Glu His Ile Lys Ile 
305                 310                 315                 320 


Val His Gly Tyr Ala Glu Lys Lys Phe Ser Cys Glu Ile Cys Glu Lys 
                325                 330                 335     


Lys Phe Tyr Thr Met Ala His Val Arg Lys His Met Val Ala His Thr 
            340                 345                 350         


Lys Asp Met Pro Phe Thr Cys Glu Thr Cys Gly Lys Ser Phe Lys Arg 
        355                 360                 365             


Ser Met Ser Leu Lys Val His Ser Leu Gln His Ser Gly Glu Lys Pro 
    370                 375                 380                 


Phe Arg Cys Glu Asn Cys Asp Glu Arg Phe Gln Tyr Lys Tyr Gln Leu 
385                 390                 395                 400 


Arg Ser His Met Ser Ile His Ile Gly His Lys Gln Phe Met Cys Gln 
                405                 410                 415     


Trp Cys Gly Lys Asp Phe Asn Met Lys Gln Tyr Phe Asp Glu His Met 
            420                 425                 430         


Lys Thr His Thr Gly Glu Lys Pro Phe Ile Cys Glu Ile Cys Gly Lys 
        435                 440                 445             


Ser Phe Thr Ser Arg Pro Asn Met Lys Arg His Arg Arg Thr His Thr 
    450                 455                 460                 


Gly Glu Lys Pro Tyr Pro Cys Asp Val Cys Gly Gln Arg Phe Arg Phe 
465                 470                 475                 480 


Ser Asn Met Leu Lys Ala His Lys Glu Lys Cys Phe Arg Val Thr Ser 
                485                 490                 495     


Pro Val Asn Val Pro Pro Ala Val Gln Ile Pro Leu Thr Thr Ser Pro 
            500                 505                 510         


Ala Thr Pro Val Pro Ser Val Val Asn Thr Ala Thr Thr Pro Thr Pro 
        515                 520                 525             


Pro Ile Asn Met Asn Pro Val Ser Thr Leu Pro Pro Arg Pro Ile Pro 
    530                 535                 540                 


His Pro Phe Ser His Leu His Ile His Pro His Pro His His Pro His 
545                 550                 555                 560 


His Leu Pro Ile Pro Pro Val Pro His Leu Pro Pro Pro Pro Ala Leu 
                565                 570                 575     


Phe Lys Ser Glu Pro Leu Asn His Arg Gly Gln Ser Glu Asp Asn Phe 
            580                 585                 590         


Leu Arg His Leu Ala Glu Lys Asn Ser Ser Ala Gln His His 
        595                 600                 605     


<210>  3277
<211>  520
<212>  PRT
<213>  homo sapiens

<400>  3277

Met Lys Ala Gly Ser Ile Asn Val Trp Asn Ile Cys Pro Leu Phe Lys 
1               5                   10                  15      


Gly Leu Gly Tyr Ala Ser Met Val Ile Val Phe Tyr Cys Asn Thr Tyr 
            20                  25                  30          


Tyr Ile Met Val Leu Ala Trp Gly Phe Tyr Tyr Leu Val Lys Ser Phe 
        35                  40                  45              


Thr Thr Thr Leu Pro Trp Ala Thr Cys Gly His Thr Trp Asn Thr Pro 
    50                  55                  60                  


Asp Cys Val Glu Ile Phe Arg His Glu Asp Cys Ala Asn Ala Ser Leu 
65                  70                  75                  80  


Ala Asn Leu Thr Cys Asp Gln Leu Ala Asp Arg Arg Ser Pro Val Ile 
                85                  90                  95      


Glu Phe Trp Glu Asn Lys Val Leu Arg Leu Ser Gly Gly Leu Glu Val 
            100                 105                 110         


Pro Gly Ala Leu Asn Trp Glu Val Thr Leu Cys Leu Leu Ala Cys Trp 
        115                 120                 125             


Val Leu Val Tyr Phe Cys Val Trp Lys Gly Val Lys Ser Thr Gly Lys 
    130                 135                 140                 


Ile Val Tyr Phe Thr Ala Thr Phe Pro Tyr Val Val Leu Val Val Leu 
145                 150                 155                 160 


Leu Val Arg Gly Val Leu Leu Pro Gly Ala Leu Asp Gly Ile Ile Tyr 
                165                 170                 175     


Tyr Leu Lys Pro Asp Trp Ser Lys Leu Gly Ser Pro Gln Val Trp Ile 
            180                 185                 190         


Asp Ala Gly Thr Gln Ile Phe Phe Ser Tyr Ala Ile Gly Leu Gly Ala 
        195                 200                 205             


Leu Thr Ala Leu Gly Ser Tyr Asn Arg Phe Asn Asn Asn Cys Tyr Lys 
    210                 215                 220                 


Asp Ala Ile Ile Leu Ala Leu Ile Asn Ser Gly Thr Ser Phe Phe Ala 
225                 230                 235                 240 


Gly Phe Val Val Phe Ser Ile Leu Gly Phe Met Ala Ala Glu Gln Gly 
                245                 250                 255     


Val His Ile Ser Lys Val Ala Glu Ser Gly Pro Gly Leu Ala Phe Ile 
            260                 265                 270         


Ala Tyr Pro Arg Ala Val Thr Leu Met Pro Val Ala Pro Leu Trp Ala 
        275                 280                 285             


Ala Leu Phe Phe Phe Met Leu Leu Leu Leu Gly Leu Asp Ser Gln Phe 
    290                 295                 300                 


Val Gly Val Glu Gly Phe Ile Thr Gly Leu Leu Asp Leu Leu Pro Ala 
305                 310                 315                 320 


Ser Tyr Tyr Phe Arg Phe Gln Arg Glu Ile Ser Val Ala Leu Cys Cys 
                325                 330                 335     


Ala Leu Cys Phe Val Ile Asp Leu Ser Met Val Thr Asp Gly Gly Met 
            340                 345                 350         


Tyr Val Phe Gln Leu Phe Asp Tyr Tyr Ser Ala Ser Gly Thr Thr Leu 
        355                 360                 365             


Leu Trp Gln Ala Phe Trp Glu Cys Val Val Val Ala Trp Val Tyr Gly 
    370                 375                 380                 


Ala Asp Arg Phe Met Asp Asp Ile Ala Cys Met Ile Gly Tyr Arg Pro 
385                 390                 395                 400 


Cys Pro Trp Met Lys Trp Cys Trp Ser Phe Phe Thr Pro Leu Val Cys 
                405                 410                 415     


Met Gly Ile Phe Ile Phe Asn Val Val Tyr Tyr Glu Pro Leu Val Tyr 
            420                 425                 430         


Asn Asn Thr Tyr Val Tyr Pro Trp Trp Gly Glu Ala Met Gly Trp Ala 
        435                 440                 445             


Phe Ala Leu Ser Ser Met Leu Cys Val Pro Leu His Leu Leu Gly Cys 
    450                 455                 460                 


Leu Leu Arg Ala Lys Gly Thr Met Ala Glu Arg Trp Gln His Leu Thr 
465                 470                 475                 480 


Gln Pro Ile Trp Gly Leu His His Leu Glu Tyr Arg Ala Gln Asp Ala 
                485                 490                 495     


Asp Val Arg Gly Leu Thr Thr Leu Thr Pro Val Ser Glu Ser Ser Lys 
            500                 505                 510         


Val Val Val Val Glu Ser Val Met 
        515                 520 


<210>  3278
<211>  750
<212>  PRT
<213>  homo sapiens

<400>  3278

Met Ser Gln Pro Gly Gln Lys Pro Ala Ala Ser Pro Arg Pro Arg Arg 
1               5                   10                  15      


Ala Ala Ala Ala Arg Arg Thr His Glu His Val Ser Glu Lys Thr Ser 
            20                  25                  30          


Glu Ser Pro Ser Lys Pro Gly Glu Lys Lys Gly Ser Asp Glu Lys Lys 
        35                  40                  45              


Ala Ala Ser Leu Gly Ser Ser Gln Ser Ser Arg Thr Tyr Ala Gly Gly 
    50                  55                  60                  


Thr Ala Ser Ala Thr Lys Val Ser Ala Ser Ser Gly Ala Thr Ser Lys 
65                  70                  75                  80  


Ser Ser Ser Met Asn Pro Thr Glu Thr Lys Ala Val Lys Thr Glu Pro 
                85                  90                  95      


Glu Lys Lys Ser Gln Ser Thr Lys Pro Lys Ser Leu Pro Lys Gln Ala 
            100                 105                 110         


Ser Asp Thr Gly Ser Asn Asp Ala His Asn Lys Lys Ala Val Ser Arg 
        115                 120                 125             


Ser Ala Glu Gln Gln Pro Ser Glu Lys Ser Thr Glu Pro Lys Thr Lys 
    130                 135                 140                 


Pro Gln Asp Met Ile Ser Ala Gly Gly Glu Ser Val Ala Gly Ile Thr 
145                 150                 155                 160 


Ala Ile Ser Gly Lys Pro Gly Asp Lys Lys Lys Glu Lys Lys Ser Leu 
                165                 170                 175     


Thr Pro Ala Val Pro Val Glu Ser Lys Pro Asp Lys Pro Ser Gly Lys 
            180                 185                 190         


Ser Gly Met Asp Ala Ala Leu Asp Asp Leu Ile Asp Thr Leu Gly Gly 
        195                 200                 205             


Pro Glu Glu Thr Glu Glu Glu Asn Thr Thr Tyr Thr Gly Pro Glu Val 
    210                 215                 220                 


Ser Asp Pro Met Ser Ser Thr Tyr Ile Glu Glu Leu Gly Lys Arg Glu 
225                 230                 235                 240 


Val Thr Ile Pro Pro Lys Tyr Arg Glu Leu Leu Ala Lys Lys Glu Gly 
                245                 250                 255     


Ile Thr Gly Pro Pro Ala Asp Ser Ser Lys Pro Ile Gly Pro Asp Asp 
            260                 265                 270         


Ala Ile Asp Ala Leu Ser Ser Asp Phe Thr Cys Gly Ser Pro Thr Ala 
        275                 280                 285             


Ala Gly Lys Lys Thr Glu Lys Glu Glu Ser Thr Glu Val Leu Lys Ala 
    290                 295                 300                 


Gln Ser Ala Gly Thr Val Arg Ser Ala Ala Pro Pro Gln Glu Lys Lys 
305                 310                 315                 320 


Arg Lys Val Glu Lys Asp Thr Met Ser Asp Gln Ala Leu Glu Ala Leu 
                325                 330                 335     


Ser Ala Ser Leu Gly Thr Arg Gln Ala Glu Pro Glu Leu Asp Leu Arg 
            340                 345                 350         


Ser Ile Lys Glu Val Asp Glu Ala Lys Ala Lys Glu Glu Lys Leu Glu 
        355                 360                 365             


Lys Cys Gly Glu Asp Asp Glu Thr Ile Pro Ser Glu Tyr Arg Leu Lys 
    370                 375                 380                 


Pro Ala Thr Asp Lys Asp Gly Lys Pro Leu Leu Pro Glu Pro Glu Glu 
385                 390                 395                 400 


Lys Pro Lys Pro Arg Ser Glu Ser Glu Leu Ile Asp Glu Leu Ser Glu 
                405                 410                 415     


Asp Phe Asp Arg Ser Glu Cys Lys Glu Lys Pro Ser Lys Pro Thr Glu 
            420                 425                 430         


Lys Thr Glu Glu Ser Lys Ala Ala Ala Pro Ala Pro Val Ser Glu Ala 
        435                 440                 445             


Val Cys Arg Thr Ser Met Cys Ser Ile Gln Ser Ala Pro Pro Glu Pro 
    450                 455                 460                 


Ala Thr Leu Lys Gly Thr Val Pro Asp Asp Ala Val Glu Ala Leu Ala 
465                 470                 475                 480 


Asp Ser Leu Gly Lys Lys Glu Ala Asp Pro Glu Asp Gly Lys Pro Val 
                485                 490                 495     


Met Asp Lys Val Lys Glu Lys Ala Lys Glu Glu Asp Arg Glu Lys Leu 
            500                 505                 510         


Gly Glu Lys Glu Glu Thr Ile Pro Pro Asp Tyr Arg Leu Glu Glu Val 
        515                 520                 525             


Lys Asp Lys Asp Gly Lys Pro Leu Leu Pro Lys Glu Ser Lys Glu Gln 
    530                 535                 540                 


Leu Pro Pro Met Ser Glu Asp Phe Leu Leu Asp Ala Leu Ser Glu Asp 
545                 550                 555                 560 


Phe Ser Gly Pro Gln Asn Ala Ser Ser Leu Lys Phe Glu Asp Ala Lys 
                565                 570                 575     


Leu Ala Ala Ala Ile Ser Glu Val Val Ser Gln Thr Pro Ala Ser Thr 
            580                 585                 590         


Thr Gln Ala Gly Ala Pro Pro Arg Asp Thr Ser Gln Ser Asp Lys Asp 
        595                 600                 605             


Leu Asp Asp Ala Leu Asp Lys Leu Ser Asp Ser Leu Gly Gln Arg Gln 
    610                 615                 620                 


Pro Asp Pro Asp Glu Asn Lys Pro Met Glu Asp Lys Val Lys Glu Lys 
625                 630                 635                 640 


Ala Lys Ala Glu His Arg Asp Lys Leu Gly Glu Arg Asp Asp Thr Ile 
                645                 650                 655     


Pro Pro Glu Tyr Arg His Leu Leu Asp Asp Asn Gly Gln Asp Lys Pro 
            660                 665                 670         


Val Lys Pro Pro Thr Lys Lys Ser Glu Asp Ser Lys Lys Pro Ala Asp 
        675                 680                 685             


Asp Gln Asp Pro Ile Asp Ala Leu Ser Gly Asp Leu Asp Ser Cys Pro 
    690                 695                 700                 


Ser Thr Thr Glu Thr Ser Gln Asn Thr Ala Lys Asp Lys Cys Lys Lys 
705                 710                 715                 720 


Ala Ala Ser Ser Ser Lys Ala Pro Lys Asn Gly Gly Lys Ala Lys Asp 
                725                 730                 735     


Ser Ala Lys Thr Thr Glu Glu Thr Ser Lys Pro Lys Asp Asp 
            740                 745                 750 


<210>  3279
<211>  172
<212>  PRT
<213>  homo sapiens

<400>  3279

Met Lys Ala Thr Ile Ile Leu Leu Leu Leu Ala Gln Val Ser Trp Ala 
1               5                   10                  15      


Gly Pro Phe Gln Gln Arg Gly Leu Phe Asp Phe Met Leu Glu Asp Glu 
            20                  25                  30          


Ala Ser Gly Ile Gly Pro Glu Val Pro Asp Asp Arg Asp Phe Glu Pro 
        35                  40                  45              


Ser Leu Gly Pro Val Cys Pro Phe Arg Cys Gln Cys His Leu Arg Val 
    50                  55                  60                  


Val Gln Cys Ser Asp Leu Gly Leu Asp Lys Val Pro Lys Asp Leu Pro 
65                  70                  75                  80  


Pro Asp Thr Thr Leu Leu Asp Leu Gln Asn Asn Lys Ile Thr Glu Ile 
                85                  90                  95      


Lys Asp Gly Asp Phe Lys Asn Leu Lys Asn Leu His Val Val Tyr Leu 
            100                 105                 110         


His Asn Asn Asn Ile Ser Val Val Gly Ser Ser Asp Phe Cys Pro Pro 
        115                 120                 125             


Gly His Asn Thr Lys Lys Ala Ser Tyr Ser Gly Val Ser Leu Phe Ser 
    130                 135                 140                 


Asn Pro Val Gln Tyr Trp Glu Ile Gln Pro Ser Thr Phe Arg Cys Val 
145                 150                 155                 160 


Tyr Val Arg Ser Ala Ile Gln Leu Gly Asn Tyr Lys 
                165                 170         


<210>  3280
<211>  1565
<212>  PRT
<213>  homo sapiens

<400>  3280

Met Leu Ser Trp Arg Leu Gln Thr Gly Pro Glu Lys Ala Glu Leu Gln 
1               5                   10                  15      


Glu Leu Asn Ala Arg Leu Tyr Asp Tyr Val Cys Arg Val Arg Glu Leu 
            20                  25                  30          


Glu Arg Glu Asn Leu Leu Leu Glu Glu Glu Leu Arg Gly Arg Arg Gly 
        35                  40                  45              


Arg Glu Gly Leu Trp Ala Glu Gly Gln Ala Arg Cys Ala Glu Glu Ala 
    50                  55                  60                  


Arg Ser Leu Arg Gln Gln Leu Asp Glu Leu Ser Trp Ala Thr Ala Leu 
65                  70                  75                  80  


Ala Glu Gly Glu Arg Asp Ala Leu Arg Arg Glu Leu Arg Glu Leu Gln 
                85                  90                  95      


Arg Leu Asp Ala Glu Glu Arg Ala Ala Arg Gly Arg Leu Asp Ala Glu 
            100                 105                 110         


Leu Gly Ala Gln Gln Arg Glu Leu Gln Glu Ala Leu Gly Ala Arg Ala 
        115                 120                 125             


Ala Leu Glu Ala Leu Leu Gly Arg Leu Gln Ala Glu Arg Arg Gly Leu 
    130                 135                 140                 


Asp Ala Ala His Glu Arg Asp Val Arg Glu Leu Arg Ala Arg Ala Ala 
145                 150                 155                 160 


Ser Leu Thr Met His Phe Arg Ala Arg Ala Thr Gly Pro Ala Ala Pro 
                165                 170                 175     


Pro Pro Arg Leu Arg Glu Val His Asp Ser Tyr Ala Leu Leu Val Ala 
            180                 185                 190         


Glu Ser Trp Arg Glu Thr Val Gln Leu Tyr Glu Asp Glu Val Arg Glu 
        195                 200                 205             


Leu Glu Glu Ala Leu Arg Arg Gly Gln Glu Ser Arg Leu Gln Ala Glu 
    210                 215                 220                 


Glu Glu Thr Arg Leu Cys Ala Gln Glu Ala Glu Ala Leu Arg Arg Glu 
225                 230                 235                 240 


Ala Leu Gly Leu Glu Gln Leu Arg Ala Arg Leu Glu Asp Ala Leu Leu 
                245                 250                 255     


Arg Met Arg Glu Glu Tyr Gly Ile Gln Ala Glu Glu Arg Gln Arg Val 
            260                 265                 270         


Ile Asp Cys Leu Glu Asp Glu Lys Ala Thr Leu Thr Leu Ala Met Ala 
        275                 280                 285             


Asp Trp Leu Arg Asp Tyr Gln Asp Leu Leu Gln Val Lys Thr Gly Leu 
    290                 295                 300                 


Ser Leu Glu Val Ala Thr Tyr Arg Ala Leu Leu Glu Gly Glu Ser Asn 
305                 310                 315                 320 


Pro Glu Ile Val Ile Trp Ala Glu His Val Glu Asn Met Pro Ser Glu 
                325                 330                 335     


Phe Arg Asn Lys Ser Tyr His Tyr Thr Asp Ser Leu Leu Gln Arg Glu 
            340                 345                 350         


Asn Glu Arg Asn Leu Phe Ser Arg Gln Lys Ala Pro Leu Ala Ser Phe 
        355                 360                 365             


Asn His Ser Ser Ala Leu Tyr Ser Asn Leu Ser Gly His Arg Gly Ser 
    370                 375                 380                 


Gln Thr Gly Thr Ser Ile Gly Gly Asp Ala Arg Arg Gly Phe Leu Gly 
385                 390                 395                 400 


Ser Gly Tyr Ser Ser Ser Ala Thr Thr Gln Gln Glu Asn Ser Tyr Gly 
                405                 410                 415     


Lys Ala Val Ser Ser Gln Thr Asn Val Arg Thr Phe Ser Pro Thr Tyr 
            420                 425                 430         


Gly Leu Leu Arg Asn Thr Glu Ala Gln Val Lys Thr Phe Pro Asp Arg 
        435                 440                 445             


Pro Lys Ala Gly Asp Thr Arg Glu Val Pro Val Tyr Ile Gly Glu Asp 
    450                 455                 460                 


Ser Thr Ile Ala Arg Glu Ser Tyr Arg Asp Arg Arg Asp Lys Val Ala 
465                 470                 475                 480 


Ala Gly Ala Ser Glu Ser Thr Arg Ser Asn Glu Arg Thr Val Ile Leu 
                485                 490                 495     


Gly Lys Lys Thr Glu Val Lys Ala Thr Arg Glu Gln Glu Arg Asn Arg 
            500                 505                 510         


Pro Glu Thr Ile Arg Thr Lys Pro Glu Glu Lys Met Phe Asp Ser Lys 
        515                 520                 525             


Glu Lys Ala Ser Glu Glu Arg Asn Leu Arg Trp Glu Glu Leu Thr Lys 
    530                 535                 540                 


Leu Asp Lys Glu Ala Arg Gln Arg Glu Ser Gln Gln Met Lys Glu Lys 
545                 550                 555                 560 


Ala Lys Glu Lys Asp Ser Pro Lys Glu Lys Ser Val Arg Glu Arg Glu 
                565                 570                 575     


Val Pro Ile Ser Leu Glu Val Ser Gln Asp Arg Arg Ala Glu Val Ser 
            580                 585                 590         


Pro Lys Gly Leu Gln Thr Pro Val Lys Asp Ala Gly Gly Gly Thr Gly 
        595                 600                 605             


Arg Glu Ala Glu Ala Arg Glu Leu Arg Phe Arg Leu Gly Thr Ser Asp 
    610                 615                 620                 


Ala Thr Gly Ser Leu Gln Gly Asp Ser Met Thr Glu Thr Val Ala Glu 
625                 630                 635                 640 


Asn Ile Val Thr Ser Ile Leu Lys Gln Phe Thr Gln Ser Pro Glu Thr 
                645                 650                 655     


Glu Ala Ser Ala Asp Ser Phe Pro Asp Thr Lys Val Thr Tyr Val Asp 
            660                 665                 670         


Arg Lys Glu Leu Pro Gly Glu Arg Lys Thr Lys Thr Glu Ile Val Val 
        675                 680                 685             


Glu Ser Lys Leu Thr Glu Asp Val Asp Val Ser Asp Glu Ala Gly Leu 
    690                 695                 700                 


Asp Tyr Leu Leu Ser Lys Asp Ile Lys Glu Val Gly Leu Lys Gly Lys 
705                 710                 715                 720 


Ser Ala Glu Gln Met Ile Gly Asp Ile Ile Asn Leu Gly Leu Lys Gly 
                725                 730                 735     


Arg Glu Gly Arg Ala Lys Val Val Asn Val Glu Ile Val Glu Glu Pro 
            740                 745                 750         


Val Ser Tyr Val Ser Gly Glu Lys Pro Glu Glu Phe Ser Val Pro Phe 
        755                 760                 765             


Lys Val Glu Glu Val Glu Asp Val Ser Pro Gly Pro Trp Gly Leu Val 
    770                 775                 780                 


Lys Glu Glu Glu Gly Tyr Gly Glu Ser Asp Val Thr Phe Ser Val Asn 
785                 790                 795                 800 


Gln His Arg Arg Thr Lys Gln Pro Gln Glu Asn Thr Thr His Val Glu 
                805                 810                 815     


Glu Val Thr Glu Ala Gly Asp Ser Glu Gly Glu Gln Ser Tyr Phe Val 
            820                 825                 830         


Ser Thr Pro Asp Glu His Pro Gly Gly His Asp Arg Asp Asp Gly Ser 
        835                 840                 845             


Val Tyr Gly Gln Ile His Ile Glu Glu Glu Ser Thr Ile Arg Tyr Ser 
    850                 855                 860                 


Trp Gln Asp Glu Ile Val Gln Gly Thr Arg Arg Arg Thr Gln Lys Asp 
865                 870                 875                 880 


Gly Ala Val Gly Glu Lys Val Val Lys Pro Leu Asp Val Pro Ala Pro 
                885                 890                 895     


Ser Leu Glu Gly Asp Leu Gly Ser Thr His Trp Lys Glu Gln Ala Arg 
            900                 905                 910         


Ser Gly Glu Phe His Ala Glu Pro Thr Val Ile Glu Lys Glu Ile Lys 
        915                 920                 925             


Ile Pro His Glu Phe His Thr Ser Met Lys Gly Ile Ser Ser Lys Glu 
    930                 935                 940                 


Pro Arg Gln Gln Leu Val Glu Val Ile Gly Gln Leu Glu Glu Thr Leu 
945                 950                 955                 960 


Pro Glu Arg Met Arg Glu Glu Leu Ser Ala Leu Thr Arg Glu Gly Gln 
                965                 970                 975     


Gly Gly Pro Gly Ser Val Ser Val Asp Val Lys Lys Val Gln Gly Ala 
            980                 985                 990         


Gly Gly Ser Ser Val Thr Leu Val  Ala Glu Val Asn Val  Ser Gln Thr 
        995                 1000                 1005             


Val Asp  Ala Asp Arg Leu Asp  Leu Glu Glu Leu Ser  Lys Asp Glu 
    1010                 1015                 1020             


Ala Ser  Glu Met Glu Lys Ala  Val Glu Ser Val Val  Arg Glu Ser 
    1025                 1030                 1035             


Leu Ser  Arg Gln Arg Ser Pro  Ala Pro Gly Ser Pro  Asp Glu Glu 
    1040                 1045                 1050             


Gly Gly  Ala Glu Ala Pro Ala  Ala Gly Ile Arg Phe  Arg Arg Trp 
    1055                 1060                 1065             


Ala Thr  Arg Glu Leu Tyr Ile  Pro Ser Gly Glu Ser  Glu Val Ala 
    1070                 1075                 1080             


Gly Gly  Ala Ser His Ser Ser  Gly Gln Arg Thr Pro  Gln Gly Pro 
    1085                 1090                 1095             


Val Ser  Ala Thr Val Glu Val  Ser Ser Pro Thr Gly  Phe Ala Gln 
    1100                 1105                 1110             


Ser Gln  Val Leu Glu Asp Val  Ser Gln Ala Ala Arg  His Ile Lys 
    1115                 1120                 1125             


Leu Gly  Pro Ser Glu Val Trp  Arg Thr Glu Arg Met  Ser Tyr Glu 
    1130                 1135                 1140             


Gly Pro  Thr Ala Glu Val Val  Glu Val Ser Ala Gly  Gly Asp Leu 
    1145                 1150                 1155             


Ser Gln  Ala Ala Ser Pro Thr  Gly Ala Ser Arg Ser  Val Arg His 
    1160                 1165                 1170             


Val Thr  Leu Gly Pro Gly Gln  Ser Pro Leu Ser Arg  Glu Val Ile 
    1175                 1180                 1185             


Phe Leu  Gly Pro Ala Pro Ala  Cys Pro Glu Ala Trp  Gly Ser Pro 
    1190                 1195                 1200             


Glu Pro  Gly Pro Ala Glu Ser  Ser Ala Asp Met Asp  Gly Ser Gly 
    1205                 1210                 1215             


Arg His  Ser Thr Phe Gly Cys  Arg Gln Phe His Ala  Glu Lys Glu 
    1220                 1225                 1230             


Ile Ile  Phe Gln Gly Pro Ile  Ser Ala Ala Gly Lys  Val Gly Asp 
    1235                 1240                 1245             


Tyr Phe  Ala Thr Glu Glu Ser  Val Gly Thr Gln Thr  Ser Val Arg 
    1250                 1255                 1260             


Gln Leu  Gln Leu Gly Pro Lys  Glu Gly Phe Ser Gly  Gln Ile Gln 
    1265                 1270                 1275             


Phe Thr  Ala Pro Leu Ser Asp  Lys Val Glu Leu Gly  Val Ile Gly 
    1280                 1285                 1290             


Asp Ser  Val His Met Glu Gly  Leu Pro Gly Ser Ser  Thr Ser Ile 
    1295                 1300                 1305             


Arg His  Ile Ser Ile Gly Pro  Gln Arg His Gln Thr  Thr Gln Gln 
    1310                 1315                 1320             


Ile Val  Tyr His Gly Leu Val  Pro Gln Leu Gly Glu  Ser Gly Asp 
    1325                 1330                 1335             


Ser Glu  Ser Thr Val His Gly  Glu Gly Ser Ala Asp  Val His Gln 
    1340                 1345                 1350             


Ala Thr  His Ser His Thr Ser  Gly Arg Gln Thr Val  Met Thr Glu 
    1355                 1360                 1365             


Lys Ser  Thr Phe Gln Ser Val  Val Ser Glu Ser Pro  Gln Glu Asp 
    1370                 1375                 1380             


Ser Ala  Glu Asp Thr Ser Gly  Ala Glu Met Thr Ser  Gly Val Ser 
    1385                 1390                 1395             


Arg Ser  Phe Arg His Ile Arg  Leu Gly Pro Thr Glu  Thr Glu Thr 
    1400                 1405                 1410             


Ser Glu  His Ile Ala Ile Arg  Gly Pro Val Ser Arg  Thr Phe Val 
    1415                 1420                 1425             


Leu Ala  Gly Ser Ala Asp Ser  Pro Glu Leu Gly Lys  Leu Ala Asp 
    1430                 1435                 1440             


Ser Ser  Arg Thr Leu Arg His  Ile Ala Pro Gly Pro  Lys Glu Thr 
    1445                 1450                 1455             


Ser Phe  Thr Phe Gln Met Asp  Val Ser Asn Val Glu  Ala Ile Arg 
    1460                 1465                 1470             


Ser Arg  Thr Gln Glu Ala Gly  Ala Leu Gly Val Ser  Asp Arg Gly 
    1475                 1480                 1485             


Ser Trp  Arg Asp Ala Asp Ser  Arg Asn Asp Gln Ala  Val Gly Val 
    1490                 1495                 1500             


Ser Phe  Lys Ala Ser Ala Gly  Glu Gly Asp Gln Ala  His Arg Glu 
    1505                 1510                 1515             


Gln Gly  Lys Glu Gln Ala Met  Phe Asp Lys Lys Val  Gln Leu Gln 
    1520                 1525                 1530             


Arg Met  Val Asp Gln Arg Ser  Val Ile Ser Asp Glu  Lys Lys Val 
    1535                 1540                 1545             


Ala Leu  Leu Tyr Leu Asp Asn  Glu Glu Glu Glu Asn  Asp Gly His 
    1550                 1555                 1560             


Trp Phe  
    1565 


<210>  3281
<211>  854
<212>  PRT
<213>  homo sapiens

<400>  3281

Met Glu Arg Pro Tyr Thr Phe Lys Asp Phe Leu Leu Arg Pro Arg Ser 
1               5                   10                  15      


His Lys Ser Arg Val Lys Gly Phe Leu Arg Leu Lys Met Ala Tyr Met 
            20                  25                  30          


Pro Lys Asn Gly Gly Gln Asp Glu Glu Asn Ser Asp Gln Arg Asp Asp 
        35                  40                  45              


Met Glu His Gly Trp Glu Val Val Asp Ser Asn Asp Ser Ala Ser Gln 
    50                  55                  60                  


His Gln Glu Glu Leu Pro Pro Pro Pro Leu Pro Pro Gly Trp Glu Glu 
65                  70                  75                  80  


Lys Val Asp Asn Leu Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg 
                85                  90                  95      


Thr Thr Gln Trp His Arg Pro Ser Leu Met Asp Val Ser Ser Glu Ser 
            100                 105                 110         


Asp Asn Asn Ile Arg Gln Ile Asn Gln Glu Ala Ala His Arg Arg Phe 
        115                 120                 125             


Arg Ser Arg Arg His Ile Ser Glu Asp Leu Glu Pro Glu Pro Ser Glu 
    130                 135                 140                 


Gly Gly Asp Val Pro Glu Pro Trp Glu Thr Ile Ser Glu Glu Val Asn 
145                 150                 155                 160 


Ile Ala Gly Asp Ser Leu Gly Leu Ala Leu Pro Pro Pro Pro Ala Ser 
                165                 170                 175     


Pro Gly Ser Arg Thr Ser Pro Gln Glu Leu Ser Glu Glu Leu Ser Arg 
            180                 185                 190         


Arg Leu Gln Ile Thr Pro Asp Ser Asn Gly Glu Gln Phe Ser Ser Leu 
        195                 200                 205             


Ile Gln Arg Glu Pro Ser Ser Arg Leu Arg Ser Cys Ser Val Thr Asp 
    210                 215                 220                 


Ala Val Ala Glu Gln Gly His Leu Pro Pro Pro Ser Ala Pro Ala Gly 
225                 230                 235                 240 


Arg Ala Arg Ser Ser Thr Val Thr Gly Gly Glu Glu Pro Thr Pro Ser 
                245                 250                 255     


Val Ala Tyr Val His Thr Thr Pro Gly Leu Pro Ser Gly Trp Glu Glu 
            260                 265                 270         


Arg Lys Asp Ala Lys Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg 
        275                 280                 285             


Thr Thr Thr Trp Thr Arg Pro Ile Met Gln Leu Ala Glu Asp Gly Ala 
    290                 295                 300                 


Ser Gly Ser Ala Thr Asn Ser Asn Asn His Leu Ile Glu Pro Gln Ile 
305                 310                 315                 320 


Arg Arg Pro Arg Ser Leu Ser Ser Pro Thr Val Thr Leu Ser Ala Pro 
                325                 330                 335     


Leu Glu Gly Ala Lys Asp Ser Pro Val Arg Arg Ala Val Lys Asp Thr 
            340                 345                 350         


Leu Ser Asn Pro Gln Ser Pro Gln Pro Ser Pro Tyr Asn Ser Pro Lys 
        355                 360                 365             


Pro Gln His Lys Val Thr Gln Ser Phe Leu Pro Pro Gly Trp Glu Met 
    370                 375                 380                 


Arg Ile Ala Pro Asn Gly Arg Pro Phe Phe Ile Asp His Asn Thr Lys 
385                 390                 395                 400 


Thr Thr Thr Trp Glu Asp Pro Arg Leu Lys Phe Pro Val His Met Arg 
                405                 410                 415     


Ser Lys Thr Ser Leu Asn Pro Asn Asp Leu Gly Pro Leu Pro Pro Gly 
            420                 425                 430         


Trp Glu Glu Arg Ile His Leu Asp Gly Arg Thr Phe Tyr Ile Asp His 
        435                 440                 445             


Asn Ser Lys Ile Thr Gln Trp Glu Asp Pro Arg Leu Gln Asn Pro Ala 
    450                 455                 460                 


Ile Thr Gly Pro Ala Val Pro Tyr Ser Arg Glu Phe Lys Gln Lys Tyr 
465                 470                 475                 480 


Asp Tyr Phe Arg Lys Lys Leu Lys Lys Pro Ala Asp Ile Pro Asn Arg 
                485                 490                 495     


Phe Glu Met Lys Leu His Arg Asn Asn Ile Phe Glu Glu Ser Tyr Arg 
            500                 505                 510         


Arg Ile Met Ser Val Lys Arg Pro Asp Val Leu Lys Ala Arg Leu Trp 
        515                 520                 525             


Ile Glu Phe Glu Ser Glu Lys Gly Leu Asp Tyr Gly Gly Val Ala Arg 
    530                 535                 540                 


Glu Trp Phe Phe Leu Leu Ser Lys Glu Met Phe Asn Pro Tyr Tyr Gly 
545                 550                 555                 560 


Leu Phe Glu Tyr Ser Ala Thr Asp Asn Tyr Thr Leu Gln Ile Asn Pro 
                565                 570                 575     


Asn Ser Gly Leu Cys Asn Glu Asp His Leu Ser Tyr Phe Thr Phe Ile 
            580                 585                 590         


Gly Arg Val Ala Gly Leu Ala Val Phe His Gly Lys Leu Leu Asp Gly 
        595                 600                 605             


Phe Phe Ile Arg Pro Phe Tyr Lys Met Met Leu Gly Lys Gln Ile Thr 
    610                 615                 620                 


Leu Asn Asp Met Glu Ser Val Asp Ser Glu Tyr Tyr Asn Ser Leu Lys 
625                 630                 635                 640 


Trp Ile Leu Glu Asn Asp Pro Thr Glu Leu Asp Leu Met Phe Cys Ile 
                645                 650                 655     


Asp Glu Glu Asn Phe Gly Gln Thr Tyr Gln Val Asp Leu Lys Pro Asn 
            660                 665                 670         


Gly Ser Glu Ile Met Val Thr Asn Glu Asn Lys Arg Glu Tyr Ile Asp 
        675                 680                 685             


Leu Val Ile Gln Trp Arg Phe Val Asn Arg Val Gln Lys Gln Met Asn 
    690                 695                 700                 


Ala Phe Leu Glu Gly Phe Thr Glu Leu Leu Pro Ile Asp Leu Ile Lys 
705                 710                 715                 720 


Ile Phe Asp Glu Asn Glu Leu Glu Leu Leu Met Cys Gly Leu Gly Asp 
                725                 730                 735     


Val Asp Val Asn Asp Trp Arg Gln His Ser Ile Tyr Lys Asn Gly Tyr 
            740                 745                 750         


Cys Pro Asn His Pro Val Ile Gln Trp Phe Trp Lys Ala Val Leu Leu 
        755                 760                 765             


Met Asp Ala Glu Lys Arg Ile Arg Leu Leu Gln Phe Val Thr Gly Thr 
    770                 775                 780                 


Ser Arg Val Pro Met Asn Gly Phe Ala Glu Leu Tyr Gly Ser Asn Gly 
785                 790                 795                 800 


Pro Gln Leu Phe Thr Ile Glu Gln Trp Gly Ser Pro Glu Lys Leu Pro 
                805                 810                 815     


Arg Ala His Thr Cys Phe Asn Arg Leu Asp Leu Pro Pro Tyr Glu Thr 
            820                 825                 830         


Phe Glu Asp Leu Arg Glu Lys Leu Leu Met Ala Val Glu Asn Ala Gln 
        835                 840                 845             


Gly Phe Glu Gly Val Asp 
    850                 


<210>  3282
<211>  562
<212>  PRT
<213>  homo sapiens

<400>  3282

Met Cys Val Cys Pro Gly Pro Arg Arg Ile Gly Ile Pro Val Arg Ser 
1               5                   10                  15      


Ser Ser Leu Pro Leu Phe Ser Asp Ala Met Pro Ala Pro Thr Gln Leu 
            20                  25                  30          


Phe Phe Pro Leu Ile Arg Asn Cys Glu Leu Ser Arg Ile Tyr Gly Thr 
        35                  40                  45              


Ala Cys Tyr Cys His His Lys His Leu Cys Cys Ser Ser Ser Tyr Ile 
    50                  55                  60                  


Pro Gln Ser Arg Leu Arg Tyr Thr Pro His Pro Ala Tyr Ala Thr Phe 
65                  70                  75                  80  


Cys Arg Pro Lys Glu Asn Trp Trp Gln Tyr Thr Gln Gly Arg Arg Tyr 
                85                  90                  95      


Ala Ser Thr Pro Gln Lys Phe Tyr Leu Thr Pro Pro Gln Val Asn Ser 
            100                 105                 110         


Ile Leu Lys Ala Asn Glu Tyr Ser Phe Lys Val Pro Glu Phe Asp Gly 
        115                 120                 125             


Lys Asn Val Ser Ser Ile Leu Gly Phe Asp Ser Asn Gln Leu Pro Ala 
    130                 135                 140                 


Asn Ala Pro Ile Glu Asp Arg Arg Ser Ala Ala Thr Cys Leu Gln Thr 
145                 150                 155                 160 


Arg Gly Met Leu Leu Gly Val Phe Asp Gly His Ala Gly Cys Ala Cys 
                165                 170                 175     


Ser Gln Ala Val Ser Glu Arg Leu Phe Tyr Tyr Ile Ala Val Ser Leu 
            180                 185                 190         


Leu Pro His Glu Thr Leu Leu Glu Ile Glu Asn Ala Val Glu Ser Gly 
        195                 200                 205             


Arg Ala Leu Leu Pro Ile Leu Gln Trp His Lys His Pro Asn Asp Tyr 
    210                 215                 220                 


Phe Ser Lys Glu Ala Ser Lys Leu Tyr Phe Asn Ser Leu Arg Thr Tyr 
225                 230                 235                 240 


Trp Gln Glu Leu Ile Asp Leu Asn Thr Gly Glu Ser Thr Asp Ile Asp 
                245                 250                 255     


Val Lys Glu Ala Leu Ile Asn Ala Phe Lys Arg Leu Asp Asn Asp Ile 
            260                 265                 270         


Ser Leu Glu Ala Gln Val Gly Asp Pro Asn Ser Phe Leu Asn Tyr Leu 
        275                 280                 285             


Val Leu Arg Val Ala Phe Ser Gly Ala Thr Ala Cys Val Ala His Val 
    290                 295                 300                 


Asp Gly Val Asp Leu His Val Ala Asn Thr Gly Asp Ser Arg Ala Met 
305                 310                 315                 320 


Leu Gly Val Gln Glu Glu Asp Gly Ser Trp Ser Ala Val Thr Leu Ser 
                325                 330                 335     


Asn Asp His Asn Ala Gln Asn Glu Arg Glu Leu Glu Arg Leu Lys Leu 
            340                 345                 350         


Glu His Pro Lys Ser Glu Ala Lys Ser Val Val Lys Gln Asp Arg Leu 
        355                 360                 365             


Leu Gly Leu Leu Met Pro Phe Arg Ala Phe Gly Asp Val Lys Phe Lys 
    370                 375                 380                 


Trp Ser Ile Asp Leu Gln Lys Arg Val Ile Glu Ser Gly Pro Asp Gln 
385                 390                 395                 400 


Leu Asn Asp Asn Glu Tyr Thr Lys Phe Ile Pro Pro Asn Tyr His Thr 
                405                 410                 415     


Pro Pro Tyr Leu Thr Ala Glu Pro Glu Val Thr Tyr His Arg Leu Arg 
            420                 425                 430         


Pro Gln Asp Lys Phe Leu Val Leu Ala Thr Asp Gly Leu Trp Glu Thr 
        435                 440                 445             


Met His Arg Gln Asp Val Val Arg Ile Val Gly Glu Tyr Leu Thr Gly 
    450                 455                 460                 


Met His His Gln Gln Pro Ile Ala Val Gly Gly Tyr Lys Val Thr Leu 
465                 470                 475                 480 


Gly Gln Met His Gly Leu Leu Thr Glu Arg Arg Thr Lys Met Ser Ser 
                485                 490                 495     


Val Phe Glu Asp Gln Asn Ala Ala Thr His Leu Ile Arg His Ala Val 
            500                 505                 510         


Gly Asn Asn Glu Phe Gly Thr Val Asp His Glu Arg Leu Ser Lys Met 
        515                 520                 525             


Leu Ser Leu Pro Glu Glu Leu Ala Arg Met Tyr Arg Asp Asp Ile Thr 
    530                 535                 540                 


Ile Ile Val Val Gln Phe Asn Ser His Val Val Gly Ala Tyr Gln Asn 
545                 550                 555                 560 


Gln Glu 
        


<210>  3283
<211>  537
<212>  PRT
<213>  homo sapiens

<400>  3283

Met Pro Ala Pro Thr Gln Leu Phe Phe Pro Leu Ile Arg Asn Cys Glu 
1               5                   10                  15      


Leu Ser Arg Ile Tyr Gly Thr Ala Cys Tyr Cys His His Lys His Leu 
            20                  25                  30          


Cys Cys Ser Ser Ser Tyr Ile Pro Gln Ser Arg Leu Arg Tyr Thr Pro 
        35                  40                  45              


His Pro Ala Tyr Ala Thr Phe Cys Arg Pro Lys Glu Asn Trp Trp Gln 
    50                  55                  60                  


Tyr Thr Gln Gly Arg Arg Tyr Ala Ser Thr Pro Gln Lys Phe Tyr Leu 
65                  70                  75                  80  


Thr Pro Pro Gln Val Asn Ser Ile Leu Lys Ala Asn Glu Tyr Ser Phe 
                85                  90                  95      


Lys Val Pro Glu Phe Asp Gly Lys Asn Val Ser Ser Ile Leu Gly Phe 
            100                 105                 110         


Asp Ser Asn Gln Leu Pro Ala Asn Ala Pro Ile Glu Asp Arg Arg Ser 
        115                 120                 125             


Ala Ala Thr Cys Leu Gln Thr Arg Gly Met Leu Leu Gly Val Phe Asp 
    130                 135                 140                 


Gly His Ala Gly Cys Ala Cys Ser Gln Ala Val Ser Glu Arg Leu Phe 
145                 150                 155                 160 


Tyr Tyr Ile Ala Val Ser Leu Leu Pro His Glu Thr Leu Leu Glu Ile 
                165                 170                 175     


Glu Asn Ala Val Glu Ser Gly Arg Ala Leu Leu Pro Ile Leu Gln Trp 
            180                 185                 190         


His Lys His Pro Asn Asp Tyr Phe Ser Lys Glu Ala Ser Lys Leu Tyr 
        195                 200                 205             


Phe Asn Ser Leu Arg Thr Tyr Trp Gln Glu Leu Ile Asp Leu Asn Thr 
    210                 215                 220                 


Gly Glu Ser Thr Asp Ile Asp Val Lys Glu Ala Leu Ile Asn Ala Phe 
225                 230                 235                 240 


Lys Arg Leu Asp Asn Asp Ile Ser Leu Glu Ala Gln Val Gly Asp Pro 
                245                 250                 255     


Asn Ser Phe Leu Asn Tyr Leu Val Leu Arg Val Ala Phe Ser Gly Ala 
            260                 265                 270         


Thr Ala Cys Val Ala His Val Asp Gly Val Asp Leu His Val Ala Asn 
        275                 280                 285             


Thr Gly Asp Ser Arg Ala Met Leu Gly Val Gln Glu Glu Asp Gly Ser 
    290                 295                 300                 


Trp Ser Ala Val Thr Leu Ser Asn Asp His Asn Ala Gln Asn Glu Arg 
305                 310                 315                 320 


Glu Leu Glu Arg Leu Lys Leu Glu His Pro Lys Ser Glu Ala Lys Ser 
                325                 330                 335     


Val Val Lys Gln Asp Arg Leu Leu Gly Leu Leu Met Pro Phe Arg Ala 
            340                 345                 350         


Phe Gly Asp Val Lys Phe Lys Trp Ser Ile Asp Leu Gln Lys Arg Val 
        355                 360                 365             


Ile Glu Ser Gly Pro Asp Gln Leu Asn Asp Asn Glu Tyr Thr Lys Phe 
    370                 375                 380                 


Ile Pro Pro Asn Tyr His Thr Pro Pro Tyr Leu Thr Ala Glu Pro Glu 
385                 390                 395                 400 


Val Thr Tyr His Arg Leu Arg Pro Gln Asp Lys Phe Leu Val Leu Ala 
                405                 410                 415     


Thr Asp Gly Leu Trp Glu Thr Met His Arg Gln Asp Val Val Arg Ile 
            420                 425                 430         


Val Gly Glu Tyr Leu Thr Gly Met His His Gln Gln Pro Ile Ala Val 
        435                 440                 445             


Gly Gly Tyr Lys Val Thr Leu Gly Gln Met His Gly Leu Leu Thr Glu 
    450                 455                 460                 


Arg Arg Thr Lys Met Ser Ser Val Phe Glu Asp Gln Asn Ala Ala Thr 
465                 470                 475                 480 


His Leu Ile Arg His Ala Val Gly Asn Asn Glu Phe Gly Thr Val Asp 
                485                 490                 495     


His Glu Arg Leu Ser Lys Met Leu Ser Leu Pro Glu Glu Leu Ala Arg 
            500                 505                 510         


Met Tyr Arg Asp Asp Ile Thr Ile Ile Val Val Gln Phe Asn Ser His 
        515                 520                 525             


Val Val Gly Ala Tyr Gln Asn Gln Glu 
    530                 535         


<210>  3284
<211>  436
<212>  PRT
<213>  homo sapiens

<400>  3284

Met Gln Asn Ser His Ser Gly Val Asn Gln Leu Gly Gly Val Phe Val 
1               5                   10                  15      


Asn Gly Arg Pro Leu Pro Asp Ser Thr Arg Gln Lys Ile Val Glu Leu 
            20                  25                  30          


Ala His Ser Gly Ala Arg Pro Cys Asp Ile Ser Arg Ile Leu Gln Thr 
        35                  40                  45              


His Ala Asp Ala Lys Val Gln Val Leu Asp Asn Gln Asn Val Ser Asn 
    50                  55                  60                  


Gly Cys Val Ser Lys Ile Leu Gly Arg Tyr Tyr Glu Thr Gly Ser Ile 
65                  70                  75                  80  


Arg Pro Arg Ala Ile Gly Gly Ser Lys Pro Arg Val Ala Thr Pro Glu 
                85                  90                  95      


Val Val Ser Lys Ile Ala Gln Tyr Lys Arg Glu Cys Pro Ser Ile Phe 
            100                 105                 110         


Ala Trp Glu Ile Arg Asp Arg Leu Leu Ser Glu Gly Val Cys Thr Asn 
        115                 120                 125             


Asp Asn Ile Pro Ser Val Ser Ser Ile Asn Arg Val Leu Arg Asn Leu 
    130                 135                 140                 


Ala Ser Glu Lys Gln Gln Met Gly Ala Asp Gly Met Tyr Asp Lys Leu 
145                 150                 155                 160 


Arg Met Leu Asn Gly Gln Thr Gly Ser Trp Gly Thr Arg Pro Gly Trp 
                165                 170                 175     


Tyr Pro Gly Thr Ser Val Pro Gly Gln Pro Thr Gln Asp Gly Cys Gln 
            180                 185                 190         


Gln Gln Glu Gly Gly Gly Glu Asn Thr Asn Ser Ile Ser Ser Asn Gly 
        195                 200                 205             


Glu Asp Ser Asp Glu Ala Gln Met Arg Leu Gln Leu Lys Arg Lys Leu 
    210                 215                 220                 


Gln Arg Asn Arg Thr Ser Phe Thr Gln Glu Gln Ile Glu Ala Leu Glu 
225                 230                 235                 240 


Lys Glu Phe Glu Arg Thr His Tyr Pro Asp Val Phe Ala Arg Glu Arg 
                245                 250                 255     


Leu Ala Ala Lys Ile Asp Leu Pro Glu Ala Arg Ile Gln Val Trp Phe 
            260                 265                 270         


Ser Asn Arg Arg Ala Lys Trp Arg Arg Glu Glu Lys Leu Arg Asn Gln 
        275                 280                 285             


Arg Arg Gln Ala Ser Asn Thr Pro Ser His Ile Pro Ile Ser Ser Ser 
    290                 295                 300                 


Phe Ser Thr Ser Val Tyr Gln Pro Ile Pro Gln Pro Thr Thr Pro Val 
305                 310                 315                 320 


Ser Ser Phe Thr Ser Gly Ser Met Leu Gly Arg Thr Asp Thr Ala Leu 
                325                 330                 335     


Thr Asn Thr Tyr Ser Ala Leu Pro Pro Met Pro Ser Phe Thr Met Ala 
            340                 345                 350         


Asn Asn Leu Pro Met Gln Pro Pro Val Pro Ser Gln Thr Ser Ser Tyr 
        355                 360                 365             


Ser Cys Met Leu Pro Thr Ser Pro Ser Val Asn Gly Arg Ser Tyr Asp 
    370                 375                 380                 


Thr Tyr Thr Pro Pro His Met Gln Thr His Met Asn Ser Gln Pro Met 
385                 390                 395                 400 


Gly Thr Ser Gly Thr Thr Ser Thr Gly Leu Ile Ser Pro Gly Val Ser 
                405                 410                 415     


Val Pro Val Gln Val Pro Gly Ser Glu Pro Asp Met Ser Gln Tyr Trp 
            420                 425                 430         


Pro Arg Leu Gln 
        435     


<210>  3285
<211>  269
<212>  PRT
<213>  homo sapiens

<400>  3285

Met Gly Asn Cys Cys Trp Thr Gln Cys Phe Gly Leu Leu Arg Lys Glu 
1               5                   10                  15      


Ala Gly Arg Leu Gln Arg Val Gly Gly Gly Gly Gly Ser Lys Tyr Phe 
            20                  25                  30          


Arg Thr Cys Ser Arg Gly Glu His Leu Thr Ile Glu Phe Glu Asn Leu 
        35                  40                  45              


Val Glu Ser Asp Glu Gly Glu Ser Pro Gly Ser Ser His Arg Pro Leu 
    50                  55                  60                  


Thr Glu Glu Glu Ile Val Asp Leu Arg Glu Arg His Tyr Asp Ser Ile 
65                  70                  75                  80  


Ala Glu Lys Gln Lys Asp Leu Asp Lys Lys Ile Gln Lys Glu Gln Glu 
                85                  90                  95      


Arg Gln Arg Ile Val Gln Gln Tyr His Pro Ser Asn Asn Gly Glu Tyr 
            100                 105                 110         


Gln Ser Ser Gly Pro Glu Asp Asp Phe Glu Ser Cys Leu Arg Asn Met 
        115                 120                 125             


Lys Ser Gln Tyr Glu Val Phe Arg Ser Ser Arg Leu Ser Ser Asp Ala 
    130                 135                 140                 


Thr Val Leu Thr Pro Asn Thr Glu Ser Ser Cys Asp Leu Met Thr Lys 
145                 150                 155                 160 


Thr Lys Ser Thr Ser Gly Asn Asp Asp Ser Thr Ser Leu Asp Leu Glu 
                165                 170                 175     


Trp Glu Asp Glu Glu Gly Met Asn Arg Met Leu Pro Met Arg Glu Arg 
            180                 185                 190         


Ser Lys Thr Glu Glu Asp Ile Leu Arg Ala Ala Leu Lys Tyr Ser Asn 
        195                 200                 205             


Lys Lys Thr Gly Ser Asn Pro Thr Ser Ala Ser Asp Asp Ser Asn Gly 
    210                 215                 220                 


Leu Glu Trp Glu Asn Asp Phe Val Ser Ala Glu Met Asp Asp Asn Gly 
225                 230                 235                 240 


Asn Ser Glu Tyr Ser Gly Phe Val Asn Pro Val Leu Glu Leu Ser Asp 
                245                 250                 255     


Ser Gly Ile Arg His Ser Asp Thr Asp Gln Gln Thr Arg 
            260                 265                 


<210>  3286
<211>  449
<212>  PRT
<213>  homo sapiens

<400>  3286

Met Met Leu Gly Thr Glu Gly Gly Glu Gly Phe Val Val Lys Val Arg 
1               5                   10                  15      


Gly Leu Pro Trp Ser Cys Ser Ala Asp Glu Val Gln Arg Phe Phe Ser 
            20                  25                  30          


Asp Cys Lys Ile Gln Asn Gly Ala Gln Gly Ile Arg Phe Ile Tyr Thr 
        35                  40                  45              


Arg Glu Gly Arg Pro Ser Gly Glu Ala Phe Val Glu Leu Glu Ser Glu 
    50                  55                  60                  


Asp Glu Val Lys Leu Ala Leu Lys Lys Asp Arg Glu Thr Met Gly His 
65                  70                  75                  80  


Arg Tyr Val Glu Val Phe Lys Ser Asn Asn Val Glu Met Asp Trp Val 
                85                  90                  95      


Leu Lys His Thr Gly Pro Asn Ser Pro Asp Thr Ala Asn Asp Gly Phe 
            100                 105                 110         


Val Arg Leu Arg Gly Leu Pro Phe Gly Cys Ser Lys Glu Glu Ile Val 
        115                 120                 125             


Gln Phe Phe Ser Gly Leu Glu Ile Val Pro Asn Gly Ile Thr Leu Pro 
    130                 135                 140                 


Val Asp Phe Gln Gly Arg Ser Thr Gly Glu Ala Phe Val Gln Phe Ala 
145                 150                 155                 160 


Ser Gln Glu Ile Ala Glu Lys Ala Leu Lys Lys His Lys Glu Arg Ile 
                165                 170                 175     


Gly His Arg Tyr Ile Glu Ile Phe Lys Ser Ser Arg Ala Glu Val Arg 
            180                 185                 190         


Thr His Tyr Asp Pro Pro Arg Lys Leu Met Ala Met Gln Arg Pro Gly 
        195                 200                 205             


Pro Tyr Asp Arg Pro Gly Ala Gly Arg Gly Tyr Asn Ser Ile Gly Arg 
    210                 215                 220                 


Gly Ala Gly Phe Glu Arg Met Arg Arg Gly Ala Tyr Gly Gly Gly Tyr 
225                 230                 235                 240 


Gly Gly Tyr Asp Asp Tyr Asn Gly Tyr Asn Asp Gly Tyr Gly Phe Gly 
                245                 250                 255     


Ser Asp Arg Phe Gly Arg Asp Leu Asn Tyr Cys Phe Ser Gly Met Ser 
            260                 265                 270         


Asp His Arg Tyr Gly Asp Gly Gly Ser Thr Phe Gln Ser Thr Thr Gly 
        275                 280                 285             


His Cys Val His Met Arg Gly Leu Pro Tyr Arg Ala Thr Glu Asn Asp 
    290                 295                 300                 


Ile Tyr Asn Phe Phe Ser Pro Leu Asn Pro Val Arg Val His Ile Glu 
305                 310                 315                 320 


Ile Gly Pro Asp Gly Arg Val Thr Gly Glu Ala Asp Val Glu Phe Ala 
                325                 330                 335     


Thr His Glu Asp Ala Val Ala Ala Met Ser Lys Asp Lys Ala Asn Met 
            340                 345                 350         


Gln His Arg Tyr Val Glu Leu Phe Leu Asn Ser Thr Ala Gly Ala Ser 
        355                 360                 365             


Gly Gly Ala Tyr Glu His Arg Tyr Val Glu Leu Phe Leu Asn Ser Thr 
    370                 375                 380                 


Ala Gly Ala Ser Gly Gly Ala Tyr Gly Ser Gln Met Met Gly Gly Met 
385                 390                 395                 400 


Gly Leu Ser Asn Gln Ser Ser Tyr Gly Gly Pro Ala Ser Gln Gln Leu 
                405                 410                 415     


Ser Gly Gly Tyr Gly Gly Gly Tyr Gly Gly Gln Ser Ser Met Ser Gly 
            420                 425                 430         


Tyr Asp Gln Val Leu Gln Glu Asn Ser Ser Asp Phe Gln Ser Asn Ile 
        435                 440                 445             


Ala 
    


<210>  3287
<211>  250
<212>  PRT
<213>  homo sapiens

<400>  3287

Met Ala Asp Asn Phe Ser Leu His Asp Ala Leu Ser Gly Ser Gly Asn 
1               5                   10                  15      


Pro Asn Pro Gln Gly Trp Pro Gly Ala Trp Gly Asn Gln Pro Ala Gly 
            20                  25                  30          


Ala Gly Gly Tyr Pro Gly Ala Ser Tyr Pro Gly Ala Tyr Pro Gly Gln 
        35                  40                  45              


Ala Pro Pro Gly Ala Tyr Pro Gly Gln Ala Pro Pro Gly Ala Tyr Pro 
    50                  55                  60                  


Gly Ala Pro Gly Ala Tyr Pro Gly Ala Pro Ala Pro Gly Val Tyr Pro 
65                  70                  75                  80  


Gly Pro Pro Ser Gly Pro Gly Ala Tyr Pro Ser Ser Gly Gln Pro Ser 
                85                  90                  95      


Ala Thr Gly Ala Tyr Pro Ala Thr Gly Pro Tyr Gly Ala Pro Ala Gly 
            100                 105                 110         


Pro Leu Ile Val Pro Tyr Asn Leu Pro Leu Pro Gly Gly Val Val Pro 
        115                 120                 125             


Arg Met Leu Ile Thr Ile Leu Gly Thr Val Lys Pro Asn Ala Asn Arg 
    130                 135                 140                 


Ile Ala Leu Asp Phe Gln Arg Gly Asn Asp Val Ala Phe His Phe Asn 
145                 150                 155                 160 


Pro Arg Phe Asn Glu Asn Asn Arg Arg Val Ile Val Cys Asn Thr Lys 
                165                 170                 175     


Leu Asp Asn Asn Trp Gly Arg Glu Glu Arg Gln Ser Val Phe Pro Phe 
            180                 185                 190         


Glu Ser Gly Lys Pro Phe Lys Ile Gln Val Leu Val Glu Pro Asp His 
        195                 200                 205             


Phe Lys Val Ala Val Asn Asp Ala His Leu Leu Gln Tyr Asn His Arg 
    210                 215                 220                 


Val Lys Lys Leu Asn Glu Ile Ser Lys Leu Gly Ile Ser Gly Asp Ile 
225                 230                 235                 240 


Asp Leu Thr Ser Ala Ser Tyr Thr Met Ile 
                245                 250 


<210>  3288
<211>  585
<212>  PRT
<213>  homo sapiens

<400>  3288

Met Thr Pro Pro Arg Leu Phe Trp Val Trp Leu Leu Val Ala Gly Thr 
1               5                   10                  15      


Gln Gly Val Asn Asp Gly Asp Met Arg Leu Ala Asp Gly Gly Ala Thr 
            20                  25                  30          


Asn Gln Gly Arg Val Glu Ile Phe Tyr Arg Gly Gln Trp Gly Thr Val 
        35                  40                  45              


Cys Asp Asn Leu Trp Asp Leu Thr Asp Ala Ser Val Val Cys Arg Ala 
    50                  55                  60                  


Leu Gly Phe Glu Asn Ala Thr Gln Ala Leu Gly Arg Ala Ala Phe Gly 
65                  70                  75                  80  


Gln Gly Ser Gly Pro Ile Met Leu Asp Glu Val Gln Cys Thr Gly Thr 
                85                  90                  95      


Glu Ala Ser Leu Ala Asp Cys Lys Ser Leu Gly Trp Leu Lys Ser Asn 
            100                 105                 110         


Cys Arg His Glu Arg Asp Ala Gly Val Val Cys Thr Asn Glu Thr Arg 
        115                 120                 125             


Ser Thr His Thr Leu Asp Leu Ser Arg Glu Leu Ser Glu Ala Leu Gly 
    130                 135                 140                 


Gln Ile Phe Asp Ser Gln Arg Gly Cys Asp Leu Ser Ile Ser Val Asn 
145                 150                 155                 160 


Val Gln Gly Glu Asp Ala Leu Gly Phe Cys Gly His Thr Val Ile Leu 
                165                 170                 175     


Thr Ala Asn Leu Glu Ala Gln Ala Leu Trp Lys Glu Pro Gly Ser Asn 
            180                 185                 190         


Val Thr Met Ser Val Asp Ala Glu Cys Val Pro Met Val Arg Asp Leu 
        195                 200                 205             


Leu Arg Tyr Phe Tyr Ser Arg Arg Ile Asp Ile Thr Leu Ser Ser Val 
    210                 215                 220                 


Lys Cys Phe His Lys Leu Ala Ser Ala Tyr Gly Ala Arg Gln Leu Gln 
225                 230                 235                 240 


Gly Tyr Cys Ala Ser Leu Phe Ala Ile Leu Leu Pro Gln Asp Pro Ser 
                245                 250                 255     


Phe Gln Met Pro Leu Asp Leu Tyr Ala Tyr Ala Val Ala Thr Gly Asp 
            260                 265                 270         


Ala Leu Leu Glu Lys Leu Cys Leu Gln Phe Leu Ala Trp Asn Phe Glu 
        275                 280                 285             


Ala Leu Thr Gln Ala Glu Ala Trp Pro Ser Val Pro Thr Asp Leu Leu 
    290                 295                 300                 


Gln Leu Leu Leu Pro Arg Ser Asp Leu Ala Val Pro Ser Glu Leu Ala 
305                 310                 315                 320 


Leu Leu Lys Ala Val Asp Thr Trp Ser Trp Gly Glu Arg Ala Ser His 
                325                 330                 335     


Glu Glu Val Glu Gly Leu Val Glu Lys Ile Arg Phe Pro Met Met Leu 
            340                 345                 350         


Pro Glu Glu Leu Phe Glu Leu Gln Phe Asn Leu Ser Leu Tyr Trp Ser 
        355                 360                 365             


His Glu Ala Leu Phe Gln Lys Lys Thr Leu Gln Ala Leu Glu Phe His 
    370                 375                 380                 


Thr Val Pro Phe Gln Leu Leu Ala Arg Tyr Lys Gly Leu Asn Leu Thr 
385                 390                 395                 400 


Glu Asp Thr Tyr Lys Pro Arg Ile Tyr Thr Ser Pro Thr Trp Ser Ala 
                405                 410                 415     


Phe Val Thr Asp Ser Ser Trp Ser Ala Arg Lys Ser Gln Leu Val Tyr 
            420                 425                 430         


Gln Ser Arg Arg Gly Pro Leu Val Lys Tyr Ser Ser Asp Tyr Phe Gln 
        435                 440                 445             


Ala Pro Ser Asp Tyr Arg Tyr Tyr Pro Tyr Gln Ser Phe Gln Thr Pro 
    450                 455                 460                 


Gln His Pro Ser Phe Leu Phe Gln Asp Lys Arg Val Ser Trp Ser Leu 
465                 470                 475                 480 


Val Tyr Leu Pro Thr Ile Gln Ser Cys Trp Asn Tyr Gly Phe Ser Cys 
                485                 490                 495     


Ser Ser Asp Glu Leu Pro Val Leu Gly Leu Thr Lys Ser Gly Gly Ser 
            500                 505                 510         


Asp Arg Thr Ile Ala Tyr Glu Asn Lys Ala Leu Met Leu Cys Glu Gly 
        515                 520                 525             


Leu Phe Val Ala Asp Val Thr Asp Phe Glu Gly Trp Lys Ala Ala Ile 
    530                 535                 540                 


Pro Ser Ala Leu Asp Thr Asn Ser Ser Lys Ser Thr Ser Ser Phe Pro 
545                 550                 555                 560 


Cys Pro Ala Gly His Phe Asn Gly Phe Arg Thr Val Ile Arg Pro Phe 
                565                 570                 575     


Tyr Leu Thr Asn Ser Ser Gly Val Asp 
            580                 585 


<210>  3289
<211>  929
<212>  PRT
<213>  homo sapiens

<400>  3289

Met Lys Lys Met Ser Arg Asn Val Leu Leu Gln Met Glu Glu Glu Glu 
1               5                   10                  15      


Asp Asp Asp Asp Gly Asp Ile Val Leu Glu Asn Leu Gly Gln Thr Ile 
            20                  25                  30          


Val Pro Asp Leu Gly Ser Leu Glu Ser Gln His Asp Phe Arg Thr Pro 
        35                  40                  45              


Glu Phe Glu Glu Phe Asn Gly Lys Pro Asp Ser Leu Phe Phe Asn Asp 
    50                  55                  60                  


Gly Gln Arg Arg Ile Asp Phe Val Leu Val Tyr Glu Asp Glu Ser Arg 
65                  70                  75                  80  


Lys Glu Thr Asn Lys Lys Gly Thr Asn Glu Lys Gln Arg Arg Lys Arg 
                85                  90                  95      


Gln Ala Tyr Glu Ser Asn Leu Ile Cys His Gly Leu Gln Leu Glu Ala 
            100                 105                 110         


Thr Arg Ser Val Leu Asp Asp Lys Leu Val Phe Val Lys Val His Ala 
        115                 120                 125             


Pro Trp Glu Val Leu Cys Thr Tyr Ala Glu Ile Met His Ile Lys Leu 
    130                 135                 140                 


Pro Leu Lys Pro Asn Asp Leu Lys Asn Arg Ser Ser Ala Phe Gly Thr 
145                 150                 155                 160 


Leu Asn Trp Phe Thr Lys Val Leu Ser Val Asp Glu Ser Ile Ile Lys 
                165                 170                 175     


Pro Glu Gln Glu Phe Phe Thr Ala Pro Phe Glu Lys Asn Arg Met Asn 
            180                 185                 190         


Asp Phe Tyr Ile Val Asp Arg Asp Ala Phe Phe Asn Pro Ala Thr Arg 
        195                 200                 205             


Ser Arg Ile Val Tyr Phe Ile Leu Ser Arg Val Lys Tyr Gln Val Ile 
    210                 215                 220                 


Asn Asn Val Ser Lys Phe Gly Ile Asn Arg Leu Val Asn Ser Gly Ile 
225                 230                 235                 240 


Tyr Lys Ala Ala Phe Pro Leu His Asp Cys Lys Phe Arg Arg Gln Ser 
                245                 250                 255     


Glu Asp Pro Ser Cys Pro Asn Glu Arg Tyr Leu Leu Tyr Arg Glu Trp 
            260                 265                 270         


Ala His Pro Arg Ser Ile Tyr Lys Lys Gln Pro Leu Asp Leu Ile Arg 
        275                 280                 285             


Lys Tyr Tyr Gly Glu Lys Ile Gly Ile Tyr Phe Ala Trp Leu Gly Tyr 
    290                 295                 300                 


Tyr Thr Gln Met Leu Leu Leu Ala Ala Val Val Gly Val Ala Cys Phe 
305                 310                 315                 320 


Leu Tyr Gly Tyr Leu Asn Gln Asp Asn Cys Thr Trp Ser Lys Glu Val 
                325                 330                 335     


Cys His Pro Asp Ile Gly Gly Lys Ile Ile Met Cys Pro Gln Cys Asp 
            340                 345                 350         


Arg Leu Cys Pro Phe Trp Lys Leu Asn Ile Thr Cys Glu Ser Ser Lys 
        355                 360                 365             


Lys Leu Cys Ile Phe Asp Ser Phe Gly Thr Leu Val Phe Ala Val Phe 
    370                 375                 380                 


Met Gly Val Trp Val Thr Leu Phe Leu Glu Phe Trp Lys Arg Arg Gln 
385                 390                 395                 400 


Ala Glu Leu Glu Tyr Glu Trp Asp Thr Val Glu Leu Gln Gln Glu Glu 
                405                 410                 415     


Gln Ala Arg Pro Glu Tyr Glu Ala Arg Cys Thr His Val Val Ile Asn 
            420                 425                 430         


Glu Ile Thr Gln Glu Glu Glu Arg Ile Pro Phe Thr Ala Trp Gly Lys 
        435                 440                 445             


Cys Ile Arg Ile Thr Leu Cys Ala Ser Ala Val Phe Phe Trp Ile Leu 
    450                 455                 460                 


Leu Ile Ile Ala Ser Val Ile Gly Ile Ile Val Tyr Arg Leu Ser Val 
465                 470                 475                 480 


Phe Ile Val Phe Ser Ala Lys Leu Pro Lys Asn Ile Asn Gly Thr Asp 
                485                 490                 495     


Pro Ile Gln Lys Tyr Leu Thr Pro Gln Thr Ala Thr Ser Ile Thr Ala 
            500                 505                 510         


Ser Ile Ile Ser Phe Ile Ile Ile Met Ile Leu Asn Thr Ile Tyr Glu 
        515                 520                 525             


Lys Val Ala Ile Met Ile Thr Asn Phe Glu Leu Pro Arg Thr Gln Thr 
    530                 535                 540                 


Asp Tyr Glu Asn Ser Leu Thr Met Lys Met Phe Leu Phe Gln Phe Val 
545                 550                 555                 560 


Asn Tyr Tyr Ser Ser Cys Phe Tyr Ile Ala Phe Phe Lys Gly Lys Phe 
                565                 570                 575     


Val Gly Tyr Pro Gly Asp Pro Val Tyr Trp Leu Gly Lys Tyr Arg Asn 
            580                 585                 590         


Glu Glu Cys Asp Pro Gly Gly Cys Leu Leu Glu Leu Thr Thr Gln Leu 
        595                 600                 605             


Thr Ile Ile Met Gly Gly Lys Ala Ile Trp Asn Asn Ile Gln Glu Val 
    610                 615                 620                 


Leu Leu Pro Trp Ile Met Asn Leu Ile Gly Arg Phe His Arg Val Ser 
625                 630                 635                 640 


Gly Ser Glu Lys Ile Thr Pro Arg Trp Glu Gln Asp Tyr His Leu Gln 
                645                 650                 655     


Pro Met Gly Lys Leu Gly Leu Phe Tyr Glu Tyr Leu Glu Met Ile Ile 
            660                 665                 670         


Gln Phe Gly Phe Val Thr Leu Phe Val Ala Ser Phe Pro Leu Ala Pro 
        675                 680                 685             


Leu Leu Ala Leu Val Asn Asn Ile Leu Glu Ile Arg Val Asp Ala Trp 
    690                 695                 700                 


Lys Leu Thr Thr Gln Phe Arg Arg Leu Val Pro Glu Lys Ala Gln Asp 
705                 710                 715                 720 


Ile Gly Ala Trp Gln Pro Ile Met Gln Gly Ile Ala Ile Leu Ala Val 
                725                 730                 735     


Val Thr Asn Ala Met Ile Ile Ala Phe Thr Ser Asp Met Ile Pro Arg 
            740                 745                 750         


Leu Val Tyr Tyr Trp Ser Phe Ser Val Pro Pro Tyr Gly Asp His Thr 
        755                 760                 765             


Ser Tyr Thr Met Glu Gly Tyr Ile Asn Asn Thr Leu Ser Ile Phe Lys 
    770                 775                 780                 


Val Ala Asp Phe Lys Asn Lys Ser Lys Gly Asn Pro Tyr Ser Asp Leu 
785                 790                 795                 800 


Gly Asn His Thr Thr Cys Arg Tyr Arg Asp Phe Arg Tyr Pro Pro Gly 
                805                 810                 815     


His Pro Gln Glu Tyr Lys His Asn Ile Tyr Tyr Trp His Val Ile Ala 
            820                 825                 830         


Ala Lys Leu Ala Phe Ile Ile Val Met Glu Tyr Leu Ala Leu Leu Pro 
        835                 840                 845             


Arg Leu Gly His Ser Gly Met Ile Leu Ala His Cys Asn Leu Arg Leu 
    850                 855                 860                 


Pro Val Asp Cys Cys Met Cys Tyr Arg Phe Val Asp Glu Ile Arg Leu 
865                 870                 875                 880 


Leu Glu Gln Leu Thr Ser Asp Phe Ile Asp Ser Leu Tyr Tyr Ile Phe 
                885                 890                 895     


Ser Ile Ser Ile Ile Ser Ile Phe Phe Ser Val Thr Phe Phe Phe Leu 
            900                 905                 910         


Leu Leu Ser Leu Gly Pro Thr Pro Cys Phe Ser Val Ser Asn Phe Leu 
        915                 920                 925             


Ser 
    


<210>  3290
<211>  346
<212>  PRT
<213>  homo sapiens

<400>  3290

Met Ala Met Val Ser Glu Phe Leu Lys Gln Ala Trp Phe Ile Glu Asn 
1               5                   10                  15      


Glu Glu Gln Glu Tyr Val Gln Thr Val Lys Ser Ser Lys Gly Gly Pro 
            20                  25                  30          


Gly Ser Ala Val Ser Pro Tyr Pro Thr Phe Asn Pro Ser Ser Asp Val 
        35                  40                  45              


Ala Ala Leu His Lys Ala Ile Met Val Lys Gly Val Asp Glu Ala Thr 
    50                  55                  60                  


Ile Ile Asp Ile Leu Thr Lys Arg Asn Asn Ala Gln Arg Gln Gln Ile 
65                  70                  75                  80  


Lys Ala Ala Tyr Leu Gln Glu Thr Gly Lys Pro Leu Asp Glu Thr Leu 
                85                  90                  95      


Lys Lys Ala Leu Thr Gly His Leu Glu Glu Val Val Leu Ala Leu Leu 
            100                 105                 110         


Lys Thr Pro Ala Gln Phe Asp Ala Asp Glu Leu Arg Ala Ala Met Lys 
        115                 120                 125             


Gly Leu Gly Thr Asp Glu Asp Thr Leu Ile Glu Ile Leu Ala Ser Arg 
    130                 135                 140                 


Thr Asn Lys Glu Ile Arg Asp Ile Asn Arg Val Tyr Arg Glu Glu Leu 
145                 150                 155                 160 


Lys Arg Asp Leu Ala Lys Asp Ile Thr Ser Asp Thr Ser Gly Asp Phe 
                165                 170                 175     


Arg Asn Ala Leu Leu Ser Leu Ala Lys Gly Asp Arg Ser Glu Asp Phe 
            180                 185                 190         


Gly Val Asn Glu Asp Leu Ala Asp Ser Asp Ala Arg Ala Leu Tyr Glu 
        195                 200                 205             


Ala Gly Glu Arg Arg Lys Gly Thr Asp Val Asn Val Phe Asn Thr Ile 
    210                 215                 220                 


Leu Thr Thr Arg Ser Tyr Pro Gln Leu Arg Arg Val Phe Gln Lys Tyr 
225                 230                 235                 240 


Thr Lys Tyr Ser Lys His Asp Met Asn Lys Val Leu Asp Leu Glu Leu 
                245                 250                 255     


Lys Gly Asp Ile Glu Lys Cys Leu Thr Ala Ile Val Lys Cys Ala Thr 
            260                 265                 270         


Ser Lys Pro Ala Phe Phe Ala Glu Lys Leu His Gln Ala Met Lys Gly 
        275                 280                 285             


Val Gly Thr Arg His Lys Ala Leu Ile Arg Ile Met Val Ser Arg Ser 
    290                 295                 300                 


Glu Ile Asp Met Asn Asp Ile Lys Ala Phe Tyr Gln Lys Met Tyr Gly 
305                 310                 315                 320 


Ile Ser Leu Cys Gln Ala Ile Leu Asp Glu Thr Lys Gly Asp Tyr Glu 
                325                 330                 335     


Lys Ile Leu Val Ala Leu Cys Gly Gly Asn 
            340                 345     


<210>  3291
<211>  505
<212>  PRT
<213>  homo sapiens

<400>  3291

Met Ser Tyr Pro Gly Tyr Pro Pro Pro Pro Gly Gly Tyr Pro Pro Ala 
1               5                   10                  15      


Ala Pro Gly Gly Gly Pro Trp Gly Gly Ala Ala Tyr Pro Pro Pro Pro 
            20                  25                  30          


Ser Met Pro Pro Ile Gly Leu Asp Asn Val Ala Thr Tyr Ala Gly Gln 
        35                  40                  45              


Phe Asn Gln Asp Tyr Leu Ser Gly Met Ala Ala Asn Met Ser Gly Thr 
    50                  55                  60                  


Phe Gly Gly Ala Asn Met Pro Asn Leu Tyr Pro Gly Ala Pro Gly Ala 
65                  70                  75                  80  


Gly Tyr Pro Pro Val Pro Pro Gly Gly Phe Gly Gln Pro Pro Ser Ala 
                85                  90                  95      


Gln Gln Pro Val Pro Pro Tyr Gly Met Tyr Pro Pro Pro Gly Gly Asn 
            100                 105                 110         


Pro Pro Ser Arg Met Pro Ser Tyr Pro Pro Tyr Pro Gly Ala Pro Val 
        115                 120                 125             


Pro Gly Gln Pro Met Pro Pro Pro Gly Gln Gln Pro Pro Gly Ala Tyr 
    130                 135                 140                 


Pro Gly Gln Pro Pro Val Thr Tyr Pro Gly Gln Pro Pro Val Pro Leu 
145                 150                 155                 160 


Pro Gly Gln Gln Gln Pro Val Pro Ser Tyr Pro Gly Tyr Pro Gly Ser 
                165                 170                 175     


Gly Thr Val Thr Pro Ala Val Pro Pro Thr Gln Phe Gly Ser Arg Gly 
            180                 185                 190         


Thr Ile Thr Asp Ala Pro Gly Phe Asp Pro Leu Arg Asp Ala Glu Val 
        195                 200                 205             


Leu Arg Lys Ala Met Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile Ile 
    210                 215                 220                 


Asp Cys Leu Gly Ser Arg Ser Asn Lys Gln Arg Gln Gln Ile Leu Leu 
225                 230                 235                 240 


Ser Phe Lys Thr Ala Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys Ser 
                245                 250                 255     


Glu Leu Ser Gly Asn Phe Glu Lys Thr Ile Leu Ala Leu Met Lys Thr 
            260                 265                 270         


Pro Val Leu Phe Asp Ile Tyr Glu Ile Lys Glu Ala Ile Lys Gly Val 
        275                 280                 285             


Gly Thr Asp Glu Ala Cys Leu Ile Glu Ile Leu Ala Ser Arg Ser Asn 
    290                 295                 300                 


Glu His Ile Arg Glu Leu Asn Arg Ala Tyr Lys Ala Glu Phe Lys Lys 
305                 310                 315                 320 


Thr Leu Glu Glu Ala Ile Arg Ser Asp Thr Ser Gly His Phe Gln Arg 
                325                 330                 335     


Leu Leu Ile Ser Leu Ser Gln Gly Asn Arg Asp Glu Ser Thr Asn Val 
            340                 345                 350         


Asp Met Ser Leu Ala Gln Arg Asp Ala Gln Glu Leu Tyr Ala Ala Gly 
        355                 360                 365             


Glu Asn Arg Leu Gly Thr Asp Glu Ser Lys Phe Asn Ala Val Leu Cys 
    370                 375                 380                 


Ser Arg Ser Arg Ala His Leu Val Ala Val Phe Asn Glu Tyr Gln Arg 
385                 390                 395                 400 


Met Thr Gly Arg Asp Ile Glu Lys Ser Ile Cys Arg Glu Met Ser Gly 
                405                 410                 415     


Asp Leu Glu Glu Gly Met Leu Ala Val Val Lys Cys Leu Lys Asn Thr 
            420                 425                 430         


Pro Ala Phe Phe Ala Glu Arg Leu Asn Lys Ala Met Arg Gly Ala Gly 
        435                 440                 445             


Thr Lys Asp Arg Thr Leu Ile Arg Ile Met Val Ser Arg Ser Glu Thr 
    450                 455                 460                 


Asp Leu Leu Asp Ile Arg Ser Glu Tyr Lys Arg Met Tyr Gly Lys Ser 
465                 470                 475                 480 


Leu Tyr His Asp Ile Ser Gly Asp Thr Ser Gly Asp Tyr Arg Lys Ile 
                485                 490                 495     


Leu Leu Lys Ile Cys Gly Gly Asn Asp 
            500                 505 


<210>  3292
<211>  505
<212>  PRT
<213>  homo sapiens

<400>  3292

Met Ser Tyr Pro Gly Tyr Pro Pro Pro Pro Gly Gly Tyr Pro Pro Ala 
1               5                   10                  15      


Ala Pro Gly Gly Gly Pro Trp Gly Gly Ala Ala Tyr Pro Pro Pro Pro 
            20                  25                  30          


Ser Met Pro Pro Ile Gly Leu Asp Asn Val Ala Thr Tyr Ala Gly Gln 
        35                  40                  45              


Phe Asn Gln Asp Tyr Leu Ser Gly Met Ala Ala Asn Met Ser Gly Thr 
    50                  55                  60                  


Phe Gly Gly Ala Asn Met Pro Asn Leu Tyr Pro Gly Ala Pro Gly Ala 
65                  70                  75                  80  


Gly Tyr Pro Pro Val Pro Pro Gly Gly Phe Gly Gln Pro Pro Ser Ala 
                85                  90                  95      


Gln Gln Pro Val Pro Pro Tyr Gly Met Tyr Pro Pro Pro Gly Gly Asn 
            100                 105                 110         


Pro Pro Ser Arg Met Pro Ser Tyr Pro Pro Tyr Pro Gly Ala Pro Val 
        115                 120                 125             


Pro Gly Gln Pro Met Pro Pro Pro Gly Gln Gln Pro Pro Gly Ala Tyr 
    130                 135                 140                 


Pro Gly Gln Pro Pro Val Thr Tyr Pro Gly Gln Pro Pro Val Pro Leu 
145                 150                 155                 160 


Pro Gly Gln Gln Gln Pro Val Pro Ser Tyr Pro Gly Tyr Pro Gly Ser 
                165                 170                 175     


Gly Thr Val Thr Pro Ala Val Pro Pro Thr Gln Phe Gly Ser Arg Gly 
            180                 185                 190         


Thr Ile Thr Asp Ala Pro Gly Phe Asp Pro Leu Arg Asp Ala Glu Val 
        195                 200                 205             


Leu Arg Lys Ala Met Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile Ile 
    210                 215                 220                 


Asp Cys Leu Gly Ser Arg Ser Asn Lys Gln Arg Gln Gln Ile Leu Leu 
225                 230                 235                 240 


Ser Phe Lys Thr Ala Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys Ser 
                245                 250                 255     


Glu Leu Ser Gly Asn Phe Glu Lys Thr Ile Leu Ala Leu Met Lys Thr 
            260                 265                 270         


Pro Val Leu Phe Asp Ile Tyr Glu Ile Lys Glu Ala Ile Lys Gly Val 
        275                 280                 285             


Gly Thr Asp Glu Ala Cys Leu Ile Glu Ile Leu Ala Ser Arg Ser Asn 
    290                 295                 300                 


Glu His Ile Arg Glu Leu Asn Arg Ala Tyr Lys Ala Glu Phe Lys Lys 
305                 310                 315                 320 


Thr Leu Glu Glu Ala Ile Arg Ser Asp Thr Ser Gly His Phe Gln Arg 
                325                 330                 335     


Leu Leu Ile Ser Leu Ser Gln Gly Asn Arg Asp Glu Ser Thr Asn Val 
            340                 345                 350         


Asp Met Ser Leu Ala Gln Arg Asp Ala Gln Glu Leu Tyr Ala Ala Gly 
        355                 360                 365             


Glu Asn Arg Leu Gly Thr Asp Glu Ser Lys Phe Asn Ala Val Leu Cys 
    370                 375                 380                 


Ser Arg Ser Arg Ala His Leu Val Ala Val Phe Asn Glu Tyr Gln Arg 
385                 390                 395                 400 


Met Thr Gly Arg Asp Ile Glu Lys Ser Ile Cys Arg Glu Met Ser Gly 
                405                 410                 415     


Asp Leu Glu Glu Gly Met Leu Ala Val Val Lys Cys Leu Lys Asn Thr 
            420                 425                 430         


Pro Ala Phe Phe Ala Glu Arg Leu Asn Lys Ala Met Arg Gly Ala Gly 
        435                 440                 445             


Thr Lys Asp Arg Thr Leu Ile Arg Ile Met Val Ser Arg Ser Glu Thr 
    450                 455                 460                 


Asp Leu Leu Asp Ile Arg Ser Glu Tyr Lys Arg Met Tyr Gly Lys Ser 
465                 470                 475                 480 


Leu Tyr His Asp Ile Ser Gly Asp Thr Ser Gly Asp Tyr Arg Lys Ile 
                485                 490                 495     


Leu Leu Lys Ile Cys Gly Gly Asn Asp 
            500                 505 


<210>  3293
<211>  505
<212>  PRT
<213>  homo sapiens

<400>  3293

Met Ser Tyr Pro Gly Tyr Pro Pro Pro Pro Gly Gly Tyr Pro Pro Ala 
1               5                   10                  15      


Ala Pro Gly Gly Gly Pro Trp Gly Gly Ala Ala Tyr Pro Pro Pro Pro 
            20                  25                  30          


Ser Met Pro Pro Ile Gly Leu Asp Asn Val Ala Thr Tyr Ala Gly Gln 
        35                  40                  45              


Phe Asn Gln Asp Tyr Leu Ser Gly Met Ala Ala Asn Met Ser Gly Thr 
    50                  55                  60                  


Phe Gly Gly Ala Asn Met Pro Asn Leu Tyr Pro Gly Ala Pro Gly Ala 
65                  70                  75                  80  


Gly Tyr Pro Pro Val Pro Pro Gly Gly Phe Gly Gln Pro Pro Ser Ala 
                85                  90                  95      


Gln Gln Pro Val Pro Pro Tyr Gly Met Tyr Pro Pro Pro Gly Gly Asn 
            100                 105                 110         


Pro Pro Ser Arg Met Pro Ser Tyr Pro Pro Tyr Pro Gly Ala Pro Val 
        115                 120                 125             


Pro Gly Gln Pro Met Pro Pro Pro Gly Gln Gln Pro Pro Gly Ala Tyr 
    130                 135                 140                 


Pro Gly Gln Pro Pro Val Thr Tyr Pro Gly Gln Pro Pro Val Pro Leu 
145                 150                 155                 160 


Pro Gly Gln Gln Gln Pro Val Pro Ser Tyr Pro Gly Tyr Pro Gly Ser 
                165                 170                 175     


Gly Thr Val Thr Pro Ala Val Pro Pro Thr Gln Phe Gly Ser Arg Gly 
            180                 185                 190         


Thr Ile Thr Asp Ala Pro Gly Phe Asp Pro Leu Arg Asp Ala Glu Val 
        195                 200                 205             


Leu Arg Lys Ala Met Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile Ile 
    210                 215                 220                 


Asp Cys Leu Gly Ser Arg Ser Asn Lys Gln Arg Gln Gln Ile Leu Leu 
225                 230                 235                 240 


Ser Phe Lys Thr Ala Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys Ser 
                245                 250                 255     


Glu Leu Ser Gly Asn Phe Glu Lys Thr Ile Leu Ala Leu Met Lys Thr 
            260                 265                 270         


Pro Val Leu Phe Asp Ile Tyr Glu Ile Lys Glu Ala Ile Lys Gly Val 
        275                 280                 285             


Gly Thr Asp Glu Ala Cys Leu Ile Glu Ile Leu Ala Ser Arg Ser Asn 
    290                 295                 300                 


Glu His Ile Arg Glu Leu Asn Arg Ala Tyr Lys Ala Glu Phe Lys Lys 
305                 310                 315                 320 


Thr Leu Glu Glu Ala Ile Arg Ser Asp Thr Ser Gly His Phe Gln Arg 
                325                 330                 335     


Leu Leu Ile Ser Leu Ser Gln Gly Asn Arg Asp Glu Ser Thr Asn Val 
            340                 345                 350         


Asp Met Ser Leu Ala Gln Arg Asp Ala Gln Glu Leu Tyr Ala Ala Gly 
        355                 360                 365             


Glu Asn Arg Leu Gly Thr Asp Glu Ser Lys Phe Asn Ala Val Leu Cys 
    370                 375                 380                 


Ser Arg Ser Arg Ala His Leu Val Ala Val Phe Asn Glu Tyr Gln Arg 
385                 390                 395                 400 


Met Thr Gly Arg Asp Ile Glu Lys Ser Ile Cys Arg Glu Met Ser Gly 
                405                 410                 415     


Asp Leu Glu Glu Gly Met Leu Ala Val Val Lys Cys Leu Lys Asn Thr 
            420                 425                 430         


Pro Ala Phe Phe Ala Glu Arg Leu Asn Lys Ala Met Arg Gly Ala Gly 
        435                 440                 445             


Thr Lys Asp Arg Thr Leu Ile Arg Ile Met Val Ser Arg Ser Glu Thr 
    450                 455                 460                 


Asp Leu Leu Asp Ile Arg Ser Glu Tyr Lys Arg Met Tyr Gly Lys Ser 
465                 470                 475                 480 


Leu Tyr His Asp Ile Ser Gly Asp Thr Ser Gly Asp Tyr Arg Lys Ile 
                485                 490                 495     


Leu Leu Lys Ile Cys Gly Gly Asn Asp 
            500                 505 


<210>  3294
<211>  339
<212>  PRT
<213>  homo sapiens

<400>  3294

Met Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu Gly Asp 
1               5                   10                  15      


His Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr Thr Asn 
            20                  25                  30          


Phe Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile Lys Thr 
        35                  40                  45              


Lys Gly Val Asp Glu Val Thr Ile Val Asn Ile Leu Thr Asn Arg Ser 
    50                  55                  60                  


Asn Ala Gln Arg Gln Asp Ile Ala Phe Ala Tyr Gln Arg Arg Thr Lys 
65                  70                  75                  80  


Lys Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His Leu Glu 
                85                  90                  95      


Thr Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp Ala Ser 
            100                 105                 110         


Glu Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp Ser Leu 
        115                 120                 125             


Ile Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu Ile Asn 
    130                 135                 140                 


Arg Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp Ile Ile 
145                 150                 155                 160 


Ser Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu Ala Lys 
                165                 170                 175     


Gly Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu Ile Asp 
            180                 185                 190         


Gln Asp Ala Arg Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys Gly Thr 
        195                 200                 205             


Asp Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val Pro His 
    210                 215                 220                 


Leu Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr Asp Met 
225                 230                 235                 240 


Leu Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn Ala Phe 
                245                 250                 255     


Leu Asn Leu Val Gln Cys Ile Gln Asn Lys Pro Leu Tyr Phe Ala Asp 
            260                 265                 270         


Arg Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys Val Leu 
        275                 280                 285             


Ile Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys Ile Arg 
    290                 295                 300                 


Ser Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr Ile Gln 
305                 310                 315                 320 


Gln Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu Cys Gly 
                325                 330                 335     


Gly Asp Asp 
            


<210>  3295
<211>  339
<212>  PRT
<213>  homo sapiens

<400>  3295

Met Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu Gly Asp 
1               5                   10                  15      


His Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr Thr Asn 
            20                  25                  30          


Phe Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile Lys Thr 
        35                  40                  45              


Lys Gly Val Asp Glu Val Thr Ile Val Asn Ile Leu Thr Asn Arg Ser 
    50                  55                  60                  


Asn Ala Gln Arg Gln Asp Ile Ala Phe Ala Tyr Gln Arg Arg Thr Lys 
65                  70                  75                  80  


Lys Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His Leu Glu 
                85                  90                  95      


Thr Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp Ala Ser 
            100                 105                 110         


Glu Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp Ser Leu 
        115                 120                 125             


Ile Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu Ile Asn 
    130                 135                 140                 


Arg Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp Ile Ile 
145                 150                 155                 160 


Ser Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu Ala Lys 
                165                 170                 175     


Gly Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu Ile Asp 
            180                 185                 190         


Gln Asp Ala Arg Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys Gly Thr 
        195                 200                 205             


Asp Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val Pro His 
    210                 215                 220                 


Leu Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr Asp Met 
225                 230                 235                 240 


Leu Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn Ala Phe 
                245                 250                 255     


Leu Asn Leu Val Gln Cys Ile Gln Asn Lys Pro Leu Tyr Phe Ala Asp 
            260                 265                 270         


Arg Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys Val Leu 
        275                 280                 285             


Ile Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys Ile Arg 
    290                 295                 300                 


Ser Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr Ile Gln 
305                 310                 315                 320 


Gln Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu Cys Gly 
                325                 330                 335     


Gly Asp Asp 
            


<210>  3296
<211>  357
<212>  PRT
<213>  homo sapiens

<400>  3296

Met Gly Arg Gln Leu Ala Gly Cys Gly Asp Ala Gly Lys Lys Ala Ser 
1               5                   10                  15      


Phe Lys Met Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu 
            20                  25                  30          


Gly Asp His Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr 
        35                  40                  45              


Thr Asn Phe Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile 
    50                  55                  60                  


Lys Thr Lys Gly Val Asp Glu Val Thr Ile Val Asn Ile Leu Thr Asn 
65                  70                  75                  80  


Arg Ser Asn Ala Gln Arg Gln Asp Ile Ala Phe Ala Tyr Gln Arg Arg 
                85                  90                  95      


Thr Lys Lys Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His 
            100                 105                 110         


Leu Glu Thr Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp 
        115                 120                 125             


Ala Ser Glu Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp 
    130                 135                 140                 


Ser Leu Ile Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu 
145                 150                 155                 160 


Ile Asn Arg Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp 
                165                 170                 175     


Ile Ile Ser Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu 
            180                 185                 190         


Ala Lys Gly Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu 
        195                 200                 205             


Ile Asp Gln Asp Ala Arg Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys 
    210                 215                 220                 


Gly Thr Asp Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val 
225                 230                 235                 240 


Pro His Leu Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr 
                245                 250                 255     


Asp Met Leu Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn 
            260                 265                 270         


Ala Phe Leu Asn Leu Val Gln Cys Ile Gln Asn Lys Pro Leu Tyr Phe 
        275                 280                 285             


Ala Asp Arg Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys 
    290                 295                 300                 


Val Leu Ile Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys 
305                 310                 315                 320 


Ile Arg Ser Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr 
                325                 330                 335     


Ile Gln Gln Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu 
            340                 345                 350         


Cys Gly Gly Asp Asp 
        355         


<210>  3297
<211>  339
<212>  PRT
<213>  homo sapiens

<400>  3297

Met Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu Gly Asp 
1               5                   10                  15      


His Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr Thr Asn 
            20                  25                  30          


Phe Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile Lys Thr 
        35                  40                  45              


Lys Gly Val Asp Glu Val Thr Ile Val Asn Ile Leu Thr Asn Arg Ser 
    50                  55                  60                  


Asn Ala Gln Arg Gln Asp Ile Ala Phe Ala Tyr Gln Arg Arg Thr Lys 
65                  70                  75                  80  


Lys Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His Leu Glu 
                85                  90                  95      


Thr Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp Ala Ser 
            100                 105                 110         


Glu Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp Ser Leu 
        115                 120                 125             


Ile Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu Ile Asn 
    130                 135                 140                 


Arg Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp Ile Ile 
145                 150                 155                 160 


Ser Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu Ala Lys 
                165                 170                 175     


Gly Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu Ile Asp 
            180                 185                 190         


Gln Asp Ala Arg Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys Gly Thr 
        195                 200                 205             


Asp Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val Pro His 
    210                 215                 220                 


Leu Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr Asp Met 
225                 230                 235                 240 


Leu Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn Ala Phe 
                245                 250                 255     


Leu Asn Leu Val Gln Cys Ile Gln Asn Lys Pro Leu Tyr Phe Ala Asp 
            260                 265                 270         


Arg Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys Val Leu 
        275                 280                 285             


Ile Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys Ile Arg 
    290                 295                 300                 


Ser Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr Ile Gln 
305                 310                 315                 320 


Gln Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu Cys Gly 
                325                 330                 335     


Gly Asp Asp 
            


<210>  3298
<211>  323
<212>  PRT
<213>  homo sapiens

<400>  3298

Met Ala Ser Ile Trp Val Gly His Arg Gly Thr Val Arg Asp Tyr Pro 
1               5                   10                  15      


Asp Phe Ser Pro Ser Val Asp Ala Glu Ala Ile Gln Lys Ala Ile Arg 
            20                  25                  30          


Gly Ile Gly Thr Asp Glu Lys Met Leu Ile Ser Ile Leu Thr Glu Arg 
        35                  40                  45              


Ser Asn Ala Gln Arg Gln Leu Ile Val Lys Glu Tyr Gln Ala Ala Tyr 
    50                  55                  60                  


Gly Lys Glu Leu Lys Asp Asp Leu Lys Gly Asp Leu Ser Gly His Phe 
65                  70                  75                  80  


Glu His Leu Met Val Ala Leu Val Thr Pro Pro Ala Val Phe Asp Ala 
                85                  90                  95      


Lys Gln Leu Lys Lys Ser Met Lys Gly Ala Gly Thr Asn Glu Asp Ala 
            100                 105                 110         


Leu Ile Glu Ile Leu Thr Thr Arg Thr Ser Arg Gln Met Lys Asp Ile 
        115                 120                 125             


Ser Gln Ala Tyr Tyr Thr Val Tyr Lys Lys Ser Leu Gly Asp Asp Ile 
    130                 135                 140                 


Ser Ser Glu Thr Ser Gly Asp Phe Arg Lys Ala Leu Leu Thr Leu Ala 
145                 150                 155                 160 


Asp Gly Arg Arg Asp Glu Ser Leu Lys Val Asp Glu His Leu Ala Lys 
                165                 170                 175     


Gln Asp Ala Gln Ile Leu Tyr Lys Ala Gly Glu Asn Arg Trp Gly Thr 
            180                 185                 190         


Asp Glu Asp Lys Phe Thr Glu Ile Leu Cys Leu Arg Ser Phe Pro Gln 
        195                 200                 205             


Leu Lys Leu Thr Phe Asp Glu Tyr Arg Asn Ile Ser Gln Lys Asp Ile 
    210                 215                 220                 


Val Asp Ser Ile Lys Gly Glu Leu Ser Gly His Phe Glu Asp Leu Leu 
225                 230                 235                 240 


Leu Ala Ile Val Asn Cys Val Arg Asn Thr Pro Ala Phe Leu Ala Glu 
                245                 250                 255     


Arg Leu His Arg Ala Leu Lys Gly Ile Gly Thr Asp Glu Phe Thr Leu 
            260                 265                 270         


Asn Arg Ile Met Val Ser Arg Ser Glu Ile Asp Leu Leu Asp Ile Arg 
        275                 280                 285             


Thr Glu Phe Lys Lys His Tyr Gly Tyr Ser Leu Tyr Ser Ala Ile Lys 
    290                 295                 300                 


Ser Asp Thr Ser Gly Asp Tyr Glu Ile Thr Leu Leu Lys Ile Cys Gly 
305                 310                 315                 320 


Gly Asp Asp 
            


<210>  3299
<211>  302
<212>  PRT
<213>  homo sapiens

<400>  3299

Met Gly Asn Cys Cys Trp Thr Gln Cys Phe Gly Leu Leu Arg Lys Glu 
1               5                   10                  15      


Ala Gly Arg Leu Gln Arg Val Gly Gly Gly Gly Gly Ser Lys Tyr Phe 
            20                  25                  30          


Arg Thr Cys Ser Arg Gly Glu His Leu Thr Ile Glu Phe Glu Asn Leu 
        35                  40                  45              


Val Glu Ser Asp Glu Gly Glu Ser Pro Gly Ser Ser His Arg Pro Leu 
    50                  55                  60                  


Thr Glu Glu Glu Ile Val Asp Leu Arg Glu Arg His Tyr Asp Ser Ile 
65                  70                  75                  80  


Ala Glu Lys Gln Lys Asp Leu Asp Lys Lys Ile Gln Lys Glu Leu Ala 
                85                  90                  95      


Leu Gln Glu Glu Lys Leu Arg Leu Glu Glu Glu Ala Leu Tyr Ala Ala 
            100                 105                 110         


Gln Arg Glu Ala Ala Arg Ala Ala Lys Gln Arg Lys Leu Leu Glu Gln 
        115                 120                 125             


Glu Arg Gln Arg Ile Val Gln Gln Tyr His Pro Ser Asn Asn Gly Glu 
    130                 135                 140                 


Tyr Gln Ser Ser Gly Pro Glu Asp Asp Phe Glu Ser Cys Leu Arg Asn 
145                 150                 155                 160 


Met Lys Ser Gln Tyr Glu Val Phe Arg Ser Ser Arg Leu Ser Ser Asp 
                165                 170                 175     


Ala Thr Val Leu Thr Pro Asn Thr Glu Ser Ser Cys Asp Leu Met Thr 
            180                 185                 190         


Lys Thr Lys Ser Thr Ser Gly Asn Asp Asp Ser Thr Ser Leu Asp Leu 
        195                 200                 205             


Glu Trp Glu Asp Glu Glu Gly Met Asn Arg Met Leu Pro Met Arg Glu 
    210                 215                 220                 


Arg Ser Lys Thr Glu Glu Asp Ile Leu Arg Ala Ala Leu Lys Tyr Ser 
225                 230                 235                 240 


Asn Lys Lys Thr Gly Ser Asn Pro Thr Ser Ala Ser Asp Asp Ser Asn 
                245                 250                 255     


Gly Leu Glu Trp Glu Asn Asp Phe Val Ser Ala Glu Met Asp Asp Asn 
            260                 265                 270         


Gly Asn Ser Glu Tyr Ser Gly Phe Val Asn Pro Val Leu Glu Leu Ser 
        275                 280                 285             


Asp Ser Gly Ile Arg His Ser Asp Thr Asp Gln Gln Thr Arg 
    290                 295                 300         


<210>  3300
<211>  565
<212>  PRT
<213>  homo sapiens

<400>  3300

Met Glu Asp Ser Asp Ser Ala Ala Lys Gln Leu Gly Leu Ala Glu Ala 
1               5                   10                  15      


Ala Ala Val Ala Ala Ala Ala Ala Val Ala Ala Ala Ala Ala Ala Ala 
            20                  25                  30          


Ala Gly Gly Glu Ala Glu Glu Pro Val Leu Ser Arg Asp Glu Asp Ser 
        35                  40                  45              


Glu Glu Asp Ala Asp Ser Glu Ala Glu Arg Glu Thr Pro Arg Val Thr 
    50                  55                  60                  


Ala Val Ala Val Met Ala Ala Glu Pro Gly His Met Asp Met Gly Ala 
65                  70                  75                  80  


Glu Ala Leu Pro Gly Pro Asp Glu Ala Ala Ala Ala Ala Ala Phe Ala 
                85                  90                  95      


Glu Val Thr Thr Val Thr Val Ala Asn Val Gly Ala Ala Ala Asp Asn 
            100                 105                 110         


Val Phe Thr Thr Ser Val Ala Asn Ala Ala Ser Ile Ser Gly His Val 
        115                 120                 125             


Leu Ser Gly Arg Thr Ala Leu Gln Ile Gly Asp Ser Leu Asn Thr Glu 
    130                 135                 140                 


Lys Ala Thr Leu Ile Val Val His Thr Asp Gly Ser Ile Val Glu Thr 
145                 150                 155                 160 


Thr Gly Leu Lys Gly Pro Ala Ala Pro Leu Thr Pro Gly Pro Gln Ser 
                165                 170                 175     


Pro Pro Thr Pro Leu Ala Pro Gly Gln Glu Lys Gly Gly Thr Lys Tyr 
            180                 185                 190         


Asn Trp Asp Pro Ser Val Tyr Asp Ser Glu Leu Pro Val Arg Cys Arg 
        195                 200                 205             


Asn Ile Ser Gly Thr Leu Tyr Lys Asn Arg Leu Gly Ser Gly Gly Arg 
    210                 215                 220                 


Gly Arg Cys Ile Lys Gln Gly Glu Asn Trp Tyr Ser Pro Thr Glu Phe 
225                 230                 235                 240 


Glu Ala Met Ala Gly Arg Ala Ser Ser Lys Asp Trp Lys Arg Ser Ile 
                245                 250                 255     


Arg Tyr Ala Gly Arg Pro Leu Gln Cys Leu Ile Gln Asp Gly Ile Leu 
            260                 265                 270         


Asn Pro His Ala Ala Ser Cys Thr Cys Ala Ala Cys Cys Asp Asp Met 
        275                 280                 285             


Thr Leu Ser Gly Pro Val Arg Leu Phe Val Pro Tyr Lys Arg Arg Lys 
    290                 295                 300                 


Lys Glu Asn Glu Leu Pro Thr Thr Pro Val Lys Lys Asp Ser Pro Lys 
305                 310                 315                 320 


Asn Ile Thr Leu Leu Pro Ala Thr Ala Ala Thr Thr Phe Thr Val Thr 
                325                 330                 335     


Pro Ser Gly Gln Ile Thr Thr Ser Gly Ala Leu Thr Phe Asp Arg Ala 
            340                 345                 350         


Ser Thr Val Glu Ala Thr Ala Val Ile Ser Glu Ser Pro Ala Gln Gly 
        355                 360                 365             


Asp Val Phe Ala Gly Ala Thr Val Gln Glu Ala Ser Val Gln Pro Pro 
    370                 375                 380                 


Cys Arg Ala Ser His Pro Glu Pro His Tyr Pro Gly Tyr Gln Asp Ser 
385                 390                 395                 400 


Cys Gln Ile Ala Pro Phe Pro Glu Ala Ala Leu Pro Thr Ser His Pro 
                405                 410                 415     


Lys Ile Val Leu Thr Ser Leu Pro Ala Leu Ala Val Pro Pro Pro Thr 
            420                 425                 430         


Pro Thr Lys Ala Ala Pro Pro Ala Leu Val Asn Gly Leu Glu Leu Ser 
        435                 440                 445             


Glu Pro Arg Ser Trp Leu Tyr Leu Glu Glu Met Val Asn Ser Leu Leu 
    450                 455                 460                 


Asn Thr Ala Gln Gln Leu Lys Thr Leu Phe Glu Gln Ala Lys His Ala 
465                 470                 475                 480 


Ser Thr Tyr Arg Glu Ala Ala Thr Asn Gln Ala Lys Ile His Ala Asp 
                485                 490                 495     


Ala Glu Arg Lys Glu Gln Ser Cys Val Asn Cys Gly Arg Glu Ala Met 
            500                 505                 510         


Ser Glu Cys Thr Gly Cys His Lys Val Asn Tyr Cys Ser Thr Phe Cys 
        515                 520                 525             


Gln Arg Lys Asp Trp Lys Asp His Gln His Ile Cys Gly Gln Ser Ala 
    530                 535                 540                 


Ala Val Thr Val Gln Ala Asp Glu Val His Val Ala Glu Ser Val Met 
545                 550                 555                 560 


Glu Lys Val Thr Val 
                565 


<210>  3301
<211>  406
<212>  PRT
<213>  homo sapiens

<400>  3301

Met Asp Gln Ser Gly Met Glu Ile Pro Val Thr Leu Ile Ile Lys Ala 
1               5                   10                  15      


Pro Asn Gln Lys Tyr Ser Asp Gln Thr Ile Ser Cys Phe Leu Asn Trp 
            20                  25                  30          


Thr Val Gly Lys Leu Lys Thr His Leu Ser Asn Val Tyr Pro Ser Lys 
        35                  40                  45              


Pro Leu Thr Lys Asp Gln Arg Leu Val Tyr Ser Gly Arg Leu Leu Pro 
    50                  55                  60                  


Asp His Leu Gln Leu Lys Asp Ile Leu Arg Lys Gln Asp Glu Tyr His 
65                  70                  75                  80  


Met Val His Leu Val Cys Thr Ser Arg Thr Pro Pro Ser Ser Pro Lys 
                85                  90                  95      


Ser Ser Thr Asn Arg Glu Ser His Glu Ala Leu Ala Ser Ser Ser Asn 
            100                 105                 110         


Ser Ser Ser Asp His Ser Gly Ser Thr Thr Pro Ser Ser Gly Gln Glu 
        115                 120                 125             


Thr Leu Ser Leu Ala Val Gly Ser Ser Ser Glu Gly Leu Arg Gln Arg 
    130                 135                 140                 


Thr Leu Pro Gln Ala Gln Thr Asp Gln Ala Gln Ser His Gln Phe Pro 
145                 150                 155                 160 


Tyr Val Met Gln Gly Asn Val Asp Asn Gln Phe Pro Gly Gln Ala Ala 
                165                 170                 175     


Pro Pro Gly Phe Pro Val Tyr Pro Ala Phe Ser Pro Leu Gln Met Leu 
            180                 185                 190         


Trp Trp Gln Gln Met Tyr Ala His Gln Tyr Tyr Met Gln Tyr Gln Ala 
        195                 200                 205             


Ala Val Ser Ala Gln Ala Thr Ser Asn Val Asn Pro Thr Gln Pro Thr 
    210                 215                 220                 


Thr Ser Gln Pro Leu Asn Leu Ala His Val Pro Gly Glu Glu Pro Pro 
225                 230                 235                 240 


Pro Ala Pro Asn Leu Val Ala Gln Glu Asn Arg Pro Met Asn Glu Asn 
                245                 250                 255     


Val Gln Met Asn Ala Gln Gly Gly Pro Val Leu Asn Glu Glu Asp Phe 
            260                 265                 270         


Asn Arg Asp Trp Leu Asp Trp Met Tyr Thr Phe Ser Arg Ala Ala Ile 
        275                 280                 285             


Leu Leu Ser Ile Val Tyr Phe Tyr Ser Ser Phe Ser Arg Phe Ile Met 
    290                 295                 300                 


Val Met Gly Ala Met Leu Leu Val Tyr Leu His Gln Ala Gly Trp Phe 
305                 310                 315                 320 


Pro Phe Arg Gln Glu Gly Gly His Gln Gln Ala Pro Asn Asn Asn Ala 
                325                 330                 335     


Glu Val Asn Asn Asp Gly Gln Asn Ala Asn Asn Leu Glu Leu Glu Glu 
            340                 345                 350         


Met Glu Arg Leu Met Asp Asp Gly Leu Glu Asp Glu Ser Gly Glu Asp 
        355                 360                 365             


Gly Gly Glu Asp Ala Ser Ala Ile Gln Arg Pro Gly Leu Met Ala Ser 
    370                 375                 380                 


Ala Trp Ser Phe Ile Thr Thr Phe Phe Thr Ser Leu Ile Pro Glu Gly 
385                 390                 395                 400 


Pro Pro Gln Val Ala Asn 
                405     


<210>  3302
<211>  1061
<212>  PRT
<213>  homo sapiens

<400>  3302

Met Leu Gly Ser Asp Asp Phe Phe Tyr Val Gly Gly Ser Pro Ser Thr 
1               5                   10                  15      


Ala Asp Leu Pro Gly Ser Pro Val Ser Asn Asn Phe Met Gly Cys Leu 
            20                  25                  30          


Lys Glu Val Val Tyr Lys Asn Asn Asp Ile Arg Leu Glu Leu Ser Arg 
        35                  40                  45              


Leu Ala Arg Ile Ala Asp Thr Lys Met Lys Ile Tyr Gly Glu Val Val 
    50                  55                  60                  


Phe Lys Cys Glu Asn Val Ala Thr Leu Asp Pro Ile Asn Phe Glu Thr 
65                  70                  75                  80  


Pro Glu Ala Tyr Ile Ser Leu Pro Lys Trp Asn Thr Lys Arg Met Gly 
                85                  90                  95      


Ser Ile Ser Phe Asp Phe Arg Thr Thr Glu Pro Asn Gly Leu Ile Leu 
            100                 105                 110         


Phe Thr His Gly Lys Pro Gln Glu Arg Lys Asp Ala Arg Ser Gln Lys 
        115                 120                 125             


Asn Thr Lys Val Asp Phe Phe Ala Val Glu Leu Leu Asp Gly Asn Leu 
    130                 135                 140                 


Tyr Leu Leu Leu Asp Met Gly Ser Gly Thr Ile Lys Val Lys Ala Thr 
145                 150                 155                 160 


Gln Lys Lys Ala Asn Asp Gly Glu Trp Tyr His Val Asp Ile Gln Arg 
                165                 170                 175     


Asp Gly Arg Ser Gly Thr Ile Ser Val Asn Ser Arg Arg Thr Pro Phe 
            180                 185                 190         


Thr Ala Ser Gly Glu Ser Glu Ile Leu Asp Leu Glu Gly Asp Met Tyr 
        195                 200                 205             


Leu Gly Gly Leu Pro Glu Asn Arg Ala Gly Leu Ile Leu Pro Thr Glu 
    210                 215                 220                 


Leu Trp Thr Ala Met Leu Asn Tyr Gly Tyr Val Gly Cys Ile Arg Asp 
225                 230                 235                 240 


Leu Phe Ile Asp Gly Arg Ser Lys Asn Ile Arg Gln Leu Ala Glu Met 
                245                 250                 255     


Gln Asn Ala Ala Gly Val Lys Ser Ser Cys Ser Arg Met Ser Ala Lys 
            260                 265                 270         


Gln Cys Asp Ser Tyr Pro Cys Lys Asn Asn Ala Val Cys Lys Asp Gly 
        275                 280                 285             


Trp Asn Arg Phe Ile Cys Asp Cys Thr Gly Thr Gly Tyr Trp Gly Arg 
    290                 295                 300                 


Thr Cys Glu Arg Glu Ala Ser Ile Leu Ser Tyr Asp Gly Ser Met Tyr 
305                 310                 315                 320 


Met Lys Ile Ile Met Pro Met Val Met His Thr Glu Ala Glu Asp Val 
                325                 330                 335     


Ser Phe Arg Phe Met Ser Gln Arg Ala Tyr Gly Leu Leu Val Ala Thr 
            340                 345                 350         


Thr Ser Arg Asp Ser Ala Asp Thr Leu Arg Leu Glu Leu Asp Gly Gly 
        355                 360                 365             


Arg Val Lys Leu Met Val Asn Leu Asp Cys Ile Arg Ile Asn Cys Asn 
    370                 375                 380                 


Ser Ser Lys Gly Pro Glu Thr Leu Tyr Ala Gly Gln Lys Leu Asn Asp 
385                 390                 395                 400 


Asn Glu Trp His Thr Val Arg Val Val Arg Arg Gly Lys Ser Leu Lys 
                405                 410                 415     


Leu Thr Val Asp Asp Asp Val Ala Glu Gly Thr Met Val Gly Asp His 
            420                 425                 430         


Thr Arg Leu Glu Phe His Asn Ile Glu Thr Gly Ile Met Thr Glu Lys 
        435                 440                 445             


Arg Tyr Ile Ser Val Val Pro Ser Ser Phe Ile Gly His Leu Gln Ser 
    450                 455                 460                 


Leu Met Phe Asn Gly Leu Leu Tyr Ile Asp Leu Cys Lys Asn Gly Asp 
465                 470                 475                 480 


Ile Asp Tyr Cys Glu Leu Lys Ala Arg Phe Gly Leu Arg Asn Ile Ile 
                485                 490                 495     


Ala Asp Pro Val Thr Phe Lys Thr Lys Ser Ser Tyr Leu Ser Leu Ala 
            500                 505                 510         


Thr Leu Gln Ala Tyr Thr Ser Met His Leu Phe Phe Gln Phe Lys Thr 
        515                 520                 525             


Thr Ser Pro Asp Gly Phe Ile Leu Phe Asn Ser Gly Asp Gly Asn Asp 
    530                 535                 540                 


Phe Ile Ala Val Glu Leu Val Lys Gly Tyr Ile His Tyr Val Phe Asp 
545                 550                 555                 560 


Leu Gly Asn Gly Pro Asn Val Ile Lys Gly Asn Ser Asp Arg Pro Leu 
                565                 570                 575     


Asn Asp Asn Gln Trp His Asn Val Val Ile Thr Arg Asp Asn Ser Asn 
            580                 585                 590         


Thr His Ser Leu Lys Val Asp Thr Lys Val Val Thr Gln Val Ile Asn 
        595                 600                 605             


Gly Ala Lys Asn Leu Asp Leu Lys Gly Asp Leu Tyr Met Ala Gly Leu 
    610                 615                 620                 


Ala Gln Gly Met Tyr Ser Asn Leu Pro Lys Leu Val Ala Ser Arg Asp 
625                 630                 635                 640 


Gly Phe Gln Gly Cys Leu Ala Ser Val Asp Leu Asn Gly Arg Leu Pro 
                645                 650                 655     


Asp Leu Ile Asn Asp Ala Leu His Arg Ser Gly Gln Ile Glu Arg Gly 
            660                 665                 670         


Cys Glu Gly Pro Ser Thr Thr Cys Gln Glu Asp Ser Cys Ala Asn Gln 
        675                 680                 685             


Gly Val Cys Met Gln Gln Trp Glu Gly Phe Thr Cys Asp Cys Ser Met 
    690                 695                 700                 


Thr Ser Tyr Ser Gly Asn Gln Cys Asn Asp Pro Gly Ala Thr Tyr Ile 
705                 710                 715                 720 


Phe Gly Lys Ser Gly Gly Leu Ile Leu Tyr Thr Trp Pro Ala Asn Asp 
                725                 730                 735     


Arg Pro Ser Thr Arg Ser Asp Arg Leu Ala Val Gly Phe Ser Thr Thr 
            740                 745                 750         


Val Lys Asp Gly Ile Leu Val Arg Ile Asp Ser Ala Pro Gly Leu Gly 
        755                 760                 765             


Asp Phe Leu Gln Leu His Ile Glu Gln Gly Lys Ile Gly Val Val Phe 
    770                 775                 780                 


Asn Ile Gly Thr Val Asp Ile Ser Ile Lys Glu Glu Arg Thr Pro Val 
785                 790                 795                 800 


Asn Asp Gly Lys Tyr His Val Val Arg Phe Thr Arg Asn Gly Gly Asn 
                805                 810                 815     


Ala Thr Leu Gln Val Asp Asn Trp Pro Val Asn Glu His Tyr Pro Thr 
            820                 825                 830         


Gly Arg Gln Leu Thr Ile Phe Asn Thr Gln Ala Gln Ile Ala Ile Gly 
        835                 840                 845             


Gly Lys Asp Lys Gly Arg Leu Phe Gln Gly Gln Leu Ser Gly Leu Tyr 
    850                 855                 860                 


Tyr Asp Gly Leu Lys Val Leu Asn Met Ala Ala Glu Asn Asn Pro Asn 
865                 870                 875                 880 


Ile Lys Ile Asn Gly Ser Val Arg Leu Val Gly Glu Val Pro Ser Ile 
                885                 890                 895     


Leu Gly Thr Thr Gln Thr Thr Ser Met Pro Pro Glu Met Ser Thr Thr 
            900                 905                 910         


Val Met Glu Thr Thr Thr Thr Met Ala Thr Thr Thr Thr Arg Lys Asn 
        915                 920                 925             


Arg Ser Thr Ala Ser Ile Gln Pro Thr Ser Asp Asp Leu Val Ser Ser 
    930                 935                 940                 


Ala Glu Cys Ser Ser Asp Asp Glu Asp Phe Val Glu Cys Glu Pro Ser 
945                 950                 955                 960 


Thr Ala Asn Pro Thr Glu Pro Gly Ile Arg Arg Val Pro Gly Ala Ser 
                965                 970                 975     


Glu Val Ile Arg Glu Ser Ser Ser Thr Thr Gly Met Val Val Gly Ile 
            980                 985                 990         


Val Ala Ala Ala Ala Leu Cys Ile  Leu Ile Leu Leu Tyr  Ala Met Tyr 
        995                 1000                 1005             


Lys Tyr  Arg Asn Arg Asp Glu  Gly Ser Tyr Gln Val  Asp Glu Thr 
    1010                 1015                 1020             


Arg Asn  Tyr Ile Ser Asn Ser  Ala Gln Ser Asn Gly  Thr Leu Met 
    1025                 1030                 1035             


Lys Glu  Lys Gln Gln Ser Ser  Lys Ser Gly His Lys  Lys Gln Lys 
    1040                 1045                 1050             


Asn Lys  Asp Arg Glu Tyr Tyr  Val 
    1055                 1060     


<210>  3303
<211>  2843
<212>  PRT
<213>  homo sapiens

<400>  3303

Met Ala Ala Ala Ser Tyr Asp Gln Leu Leu Lys Gln Val Glu Ala Leu 
1               5                   10                  15      


Lys Met Glu Asn Ser Asn Leu Arg Gln Glu Leu Glu Asp Asn Ser Asn 
            20                  25                  30          


His Leu Thr Lys Leu Glu Thr Glu Ala Ser Asn Met Lys Glu Val Leu 
        35                  40                  45              


Lys Gln Leu Gln Gly Ser Ile Glu Asp Glu Ala Met Ala Ser Ser Gly 
    50                  55                  60                  


Gln Ile Asp Leu Leu Glu Arg Leu Lys Glu Leu Asn Leu Asp Ser Ser 
65                  70                  75                  80  


Asn Phe Pro Gly Val Lys Leu Arg Ser Lys Met Ser Leu Arg Ser Tyr 
                85                  90                  95      


Gly Ser Arg Glu Gly Ser Val Ser Ser Arg Ser Gly Glu Cys Ser Pro 
            100                 105                 110         


Val Pro Met Gly Ser Phe Pro Arg Arg Gly Phe Val Asn Gly Ser Arg 
        115                 120                 125             


Glu Ser Thr Gly Tyr Leu Glu Glu Leu Glu Lys Glu Arg Ser Leu Leu 
    130                 135                 140                 


Leu Ala Asp Leu Asp Lys Glu Glu Lys Glu Lys Asp Trp Tyr Tyr Ala 
145                 150                 155                 160 


Gln Leu Gln Asn Leu Thr Lys Arg Ile Asp Ser Leu Pro Leu Thr Glu 
                165                 170                 175     


Asn Phe Ser Leu Gln Thr Asp Met Thr Arg Arg Gln Leu Glu Tyr Glu 
            180                 185                 190         


Ala Arg Gln Ile Arg Val Ala Met Glu Glu Gln Leu Gly Thr Cys Gln 
        195                 200                 205             


Asp Met Glu Lys Arg Ala Gln Arg Arg Ile Ala Arg Ile Gln Gln Ile 
    210                 215                 220                 


Glu Lys Asp Ile Leu Arg Ile Arg Gln Leu Leu Gln Ser Gln Ala Thr 
225                 230                 235                 240 


Glu Ala Glu Arg Ser Ser Gln Asn Lys His Glu Thr Gly Ser His Asp 
                245                 250                 255     


Ala Glu Arg Gln Asn Glu Gly Gln Gly Val Gly Glu Ile Asn Met Ala 
            260                 265                 270         


Thr Ser Gly Asn Gly Gln Gly Ser Thr Thr Arg Met Asp His Glu Thr 
        275                 280                 285             


Ala Ser Val Leu Ser Ser Ser Ser Thr His Ser Ala Pro Arg Arg Leu 
    290                 295                 300                 


Thr Ser His Leu Gly Thr Lys Val Glu Met Val Tyr Ser Leu Leu Ser 
305                 310                 315                 320 


Met Leu Gly Thr His Asp Lys Asp Asp Met Ser Arg Thr Leu Leu Ala 
                325                 330                 335     


Met Ser Ser Ser Gln Asp Ser Cys Ile Ser Met Arg Gln Ser Gly Cys 
            340                 345                 350         


Leu Pro Leu Leu Ile Gln Leu Leu His Gly Asn Asp Lys Asp Ser Val 
        355                 360                 365             


Leu Leu Gly Asn Ser Arg Gly Ser Lys Glu Ala Arg Ala Arg Ala Ser 
    370                 375                 380                 


Ala Ala Leu His Asn Ile Ile His Ser Gln Pro Asp Asp Lys Arg Gly 
385                 390                 395                 400 


Arg Arg Glu Ile Arg Val Leu His Leu Leu Glu Gln Ile Arg Ala Tyr 
                405                 410                 415     


Cys Glu Thr Cys Trp Glu Trp Gln Glu Ala His Glu Pro Gly Met Asp 
            420                 425                 430         


Gln Asp Lys Asn Pro Met Pro Ala Pro Val Glu His Gln Ile Cys Pro 
        435                 440                 445             


Ala Val Cys Val Leu Met Lys Leu Ser Phe Asp Glu Glu His Arg His 
    450                 455                 460                 


Ala Met Asn Glu Leu Gly Gly Leu Gln Ala Ile Ala Glu Leu Leu Gln 
465                 470                 475                 480 


Val Asp Cys Glu Met Tyr Gly Leu Thr Asn Asp His Tyr Ser Ile Thr 
                485                 490                 495     


Leu Arg Arg Tyr Ala Gly Met Ala Leu Thr Asn Leu Thr Phe Gly Asp 
            500                 505                 510         


Val Ala Asn Lys Ala Thr Leu Cys Ser Met Lys Gly Cys Met Arg Ala 
        515                 520                 525             


Leu Val Ala Gln Leu Lys Ser Glu Ser Glu Asp Leu Gln Gln Val Ile 
    530                 535                 540                 


Ala Ser Val Leu Arg Asn Leu Ser Trp Arg Ala Asp Val Asn Ser Lys 
545                 550                 555                 560 


Lys Thr Leu Arg Glu Val Gly Ser Val Lys Ala Leu Met Glu Cys Ala 
                565                 570                 575     


Leu Glu Val Lys Lys Glu Ser Thr Leu Lys Ser Val Leu Ser Ala Leu 
            580                 585                 590         


Trp Asn Leu Ser Ala His Cys Thr Glu Asn Lys Ala Asp Ile Cys Ala 
        595                 600                 605             


Val Asp Gly Ala Leu Ala Phe Leu Val Gly Thr Leu Thr Tyr Arg Ser 
    610                 615                 620                 


Gln Thr Asn Thr Leu Ala Ile Ile Glu Ser Gly Gly Gly Ile Leu Arg 
625                 630                 635                 640 


Asn Val Ser Ser Leu Ile Ala Thr Asn Glu Asp His Arg Gln Ile Leu 
                645                 650                 655     


Arg Glu Asn Asn Cys Leu Gln Thr Leu Leu Gln His Leu Lys Ser His 
            660                 665                 670         


Ser Leu Thr Ile Val Ser Asn Ala Cys Gly Thr Leu Trp Asn Leu Ser 
        675                 680                 685             


Ala Arg Asn Pro Lys Asp Gln Glu Ala Leu Trp Asp Met Gly Ala Val 
    690                 695                 700                 


Ser Met Leu Lys Asn Leu Ile His Ser Lys His Lys Met Ile Ala Met 
705                 710                 715                 720 


Gly Ser Ala Ala Ala Leu Arg Asn Leu Met Ala Asn Arg Pro Ala Lys 
                725                 730                 735     


Tyr Lys Asp Ala Asn Ile Met Ser Pro Gly Ser Ser Leu Pro Ser Leu 
            740                 745                 750         


His Val Arg Lys Gln Lys Ala Leu Glu Ala Glu Leu Asp Ala Gln His 
        755                 760                 765             


Leu Ser Glu Thr Phe Asp Asn Ile Asp Asn Leu Ser Pro Lys Ala Ser 
    770                 775                 780                 


His Arg Ser Lys Gln Arg His Lys Gln Ser Leu Tyr Gly Asp Tyr Val 
785                 790                 795                 800 


Phe Asp Thr Asn Arg His Asp Asp Asn Arg Ser Asp Asn Phe Asn Thr 
                805                 810                 815     


Gly Asn Met Thr Val Leu Ser Pro Tyr Leu Asn Thr Thr Val Leu Pro 
            820                 825                 830         


Ser Ser Ser Ser Ser Arg Gly Ser Leu Asp Ser Ser Arg Ser Glu Lys 
        835                 840                 845             


Asp Arg Ser Leu Glu Arg Glu Arg Gly Ile Gly Leu Gly Asn Tyr His 
    850                 855                 860                 


Pro Ala Thr Glu Asn Pro Gly Thr Ser Ser Lys Arg Gly Leu Gln Ile 
865                 870                 875                 880 


Ser Thr Thr Ala Ala Gln Ile Ala Lys Val Met Glu Glu Val Ser Ala 
                885                 890                 895     


Ile His Thr Ser Gln Glu Asp Arg Ser Ser Gly Ser Thr Thr Glu Leu 
            900                 905                 910         


His Cys Val Thr Asp Glu Arg Asn Ala Leu Arg Arg Ser Ser Ala Ala 
        915                 920                 925             


His Thr His Ser Asn Thr Tyr Asn Phe Thr Lys Ser Glu Asn Ser Asn 
    930                 935                 940                 


Arg Thr Cys Ser Met Pro Tyr Ala Lys Leu Glu Tyr Lys Arg Ser Ser 
945                 950                 955                 960 


Asn Asp Ser Leu Asn Ser Val Ser Ser Ser Asp Gly Tyr Gly Lys Arg 
                965                 970                 975     


Gly Gln Met Lys Pro Ser Ile Glu Ser Tyr Ser Glu Asp Asp Glu Ser 
            980                 985                 990         


Lys Phe Cys Ser Tyr Gly Gln Tyr  Pro Ala Asp Leu Ala  His Lys Ile 
        995                 1000                 1005             


His Ser  Ala Asn His Met Asp  Asp Asn Asp Gly Glu  Leu Asp Thr 
    1010                 1015                 1020             


Pro Ile  Asn Tyr Ser Leu Lys  Tyr Ser Asp Glu Gln  Leu Asn Ser 
    1025                 1030                 1035             


Gly Arg  Gln Ser Pro Ser Gln  Asn Glu Arg Trp Ala  Arg Pro Lys 
    1040                 1045                 1050             


His Ile  Ile Glu Asp Glu Ile  Lys Gln Ser Glu Gln  Arg Gln Ser 
    1055                 1060                 1065             


Arg Asn  Gln Ser Thr Thr Tyr  Pro Val Tyr Thr Glu  Ser Thr Asp 
    1070                 1075                 1080             


Asp Lys  His Leu Lys Phe Gln  Pro His Phe Gly Gln  Gln Glu Cys 
    1085                 1090                 1095             


Val Ser  Pro Tyr Arg Ser Arg  Gly Ala Asn Gly Ser  Glu Thr Asn 
    1100                 1105                 1110             


Arg Val  Gly Ser Asn His Gly  Ile Asn Gln Asn Val  Ser Gln Ser 
    1115                 1120                 1125             


Leu Cys  Gln Glu Asp Asp Tyr  Glu Asp Asp Lys Pro  Thr Asn Tyr 
    1130                 1135                 1140             


Ser Glu  Arg Tyr Ser Glu Glu  Glu Gln His Glu Glu  Glu Glu Arg 
    1145                 1150                 1155             


Pro Thr  Asn Tyr Ser Ile Lys  Tyr Asn Glu Glu Lys  Arg His Val 
    1160                 1165                 1170             


Asp Gln  Pro Ile Asp Tyr Ser  Leu Lys Tyr Ala Thr  Asp Ile Pro 
    1175                 1180                 1185             


Ser Ser  Gln Lys Gln Ser Phe  Ser Phe Ser Lys Ser  Ser Ser Gly 
    1190                 1195                 1200             


Gln Ser  Ser Lys Thr Glu His  Met Ser Ser Ser Ser  Glu Asn Thr 
    1205                 1210                 1215             


Ser Thr  Pro Ser Ser Asn Ala  Lys Arg Gln Asn Gln  Leu His Pro 
    1220                 1225                 1230             


Ser Ser  Ala Gln Ser Arg Ser  Gly Gln Pro Gln Lys  Ala Ala Thr 
    1235                 1240                 1245             


Cys Lys  Val Ser Ser Ile Asn  Gln Glu Thr Ile Gln  Thr Tyr Cys 
    1250                 1255                 1260             


Val Glu  Asp Thr Pro Ile Cys  Phe Ser Arg Cys Ser  Ser Leu Ser 
    1265                 1270                 1275             


Ser Leu  Ser Ser Ala Glu Asp  Glu Ile Gly Cys Asn  Gln Thr Thr 
    1280                 1285                 1290             


Gln Glu  Ala Asp Ser Ala Asn  Thr Leu Gln Ile Ala  Glu Ile Lys 
    1295                 1300                 1305             


Glu Lys  Ile Gly Thr Arg Ser  Ala Glu Asp Pro Val  Ser Glu Val 
    1310                 1315                 1320             


Pro Ala  Val Ser Gln His Pro  Arg Thr Lys Ser Ser  Arg Leu Gln 
    1325                 1330                 1335             


Gly Ser  Ser Leu Ser Ser Glu  Ser Ala Arg His Lys  Ala Val Glu 
    1340                 1345                 1350             


Phe Ser  Ser Gly Ala Lys Ser  Pro Ser Lys Ser Gly  Ala Gln Thr 
    1355                 1360                 1365             


Pro Lys  Ser Pro Pro Glu His  Tyr Val Gln Glu Thr  Pro Leu Met 
    1370                 1375                 1380             


Phe Ser  Arg Cys Thr Ser Val  Ser Ser Leu Asp Ser  Phe Glu Ser 
    1385                 1390                 1395             


Arg Ser  Ile Ala Ser Ser Val  Gln Ser Glu Pro Cys  Ser Gly Met 
    1400                 1405                 1410             


Val Ser  Gly Ile Ile Ser Pro  Ser Asp Leu Pro Asp  Ser Pro Gly 
    1415                 1420                 1425             


Gln Thr  Met Pro Pro Ser Arg  Ser Lys Thr Pro Pro  Pro Pro Pro 
    1430                 1435                 1440             


Gln Thr  Ala Gln Thr Lys Arg  Glu Val Pro Lys Asn  Lys Ala Pro 
    1445                 1450                 1455             


Thr Ala  Glu Lys Arg Glu Ser  Gly Pro Lys Gln Ala  Ala Val Asn 
    1460                 1465                 1470             


Ala Ala  Val Gln Arg Val Gln  Val Leu Pro Asp Ala  Asp Thr Leu 
    1475                 1480                 1485             


Leu His  Phe Ala Thr Glu Ser  Thr Pro Asp Gly Phe  Ser Cys Ser 
    1490                 1495                 1500             


Ser Ser  Leu Ser Ala Leu Ser  Leu Asp Glu Pro Phe  Ile Gln Lys 
    1505                 1510                 1515             


Asp Val  Glu Leu Arg Ile Met  Pro Pro Val Gln Glu  Asn Asp Asn 
    1520                 1525                 1530             


Gly Asn  Glu Thr Glu Ser Glu  Gln Pro Lys Glu Ser  Asn Glu Asn 
    1535                 1540                 1545             


Gln Glu  Lys Glu Ala Glu Lys  Thr Ile Asp Ser Glu  Lys Asp Leu 
    1550                 1555                 1560             


Leu Asp  Asp Ser Asp Asp Asp  Asp Ile Glu Ile Leu  Glu Glu Cys 
    1565                 1570                 1575             


Ile Ile  Ser Ala Met Pro Thr  Lys Ser Ser Arg Lys  Ala Lys Lys 
    1580                 1585                 1590             


Pro Ala  Gln Thr Ala Ser Lys  Leu Pro Pro Pro Val  Ala Arg Lys 
    1595                 1600                 1605             


Pro Ser  Gln Leu Pro Val Tyr  Lys Leu Leu Pro Ser  Gln Asn Arg 
    1610                 1615                 1620             


Leu Gln  Pro Gln Lys His Val  Ser Phe Thr Pro Gly  Asp Asp Met 
    1625                 1630                 1635             


Pro Arg  Val Tyr Cys Val Glu  Gly Thr Pro Ile Asn  Phe Ser Thr 
    1640                 1645                 1650             


Ala Thr  Ser Leu Ser Asp Leu  Thr Ile Glu Ser Pro  Pro Asn Glu 
    1655                 1660                 1665             


Leu Ala  Ala Gly Glu Gly Val  Arg Gly Gly Ala Gln  Ser Gly Glu 
    1670                 1675                 1680             


Phe Glu  Lys Arg Asp Thr Ile  Pro Thr Glu Gly Arg  Ser Thr Asp 
    1685                 1690                 1695             


Glu Ala  Gln Gly Gly Lys Thr  Ser Ser Val Thr Ile  Pro Glu Leu 
    1700                 1705                 1710             


Asp Asp  Asn Lys Ala Glu Glu  Gly Asp Ile Leu Ala  Glu Cys Ile 
    1715                 1720                 1725             


Asn Ser  Ala Met Pro Lys Gly  Lys Ser His Lys Pro  Phe Arg Val 
    1730                 1735                 1740             


Lys Lys  Ile Met Asp Gln Val  Gln Gln Ala Ser Ala  Ser Ser Ser 
    1745                 1750                 1755             


Ala Pro  Asn Lys Asn Gln Leu  Asp Gly Lys Lys Lys  Lys Pro Thr 
    1760                 1765                 1770             


Ser Pro  Val Lys Pro Ile Pro  Gln Asn Thr Glu Tyr  Arg Thr Arg 
    1775                 1780                 1785             


Val Arg  Lys Asn Ala Asp Ser  Lys Asn Asn Leu Asn  Ala Glu Arg 
    1790                 1795                 1800             


Val Phe  Ser Asp Asn Lys Asp  Ser Lys Lys Gln Asn  Leu Lys Asn 
    1805                 1810                 1815             


Asn Ser  Lys Val Phe Asn Asp  Lys Leu Pro Asn Asn  Glu Asp Arg 
    1820                 1825                 1830             


Val Arg  Gly Ser Phe Ala Phe  Asp Ser Pro His His  Tyr Thr Pro 
    1835                 1840                 1845             


Ile Glu  Gly Thr Pro Tyr Cys  Phe Ser Arg Asn Asp  Ser Leu Ser 
    1850                 1855                 1860             


Ser Leu  Asp Phe Asp Asp Asp  Asp Val Asp Leu Ser  Arg Glu Lys 
    1865                 1870                 1875             


Ala Glu  Leu Arg Lys Ala Lys  Glu Asn Lys Glu Ser  Glu Ala Lys 
    1880                 1885                 1890             


Val Thr  Ser His Thr Glu Leu  Thr Ser Asn Gln Gln  Ser Ala Asn 
    1895                 1900                 1905             


Lys Thr  Gln Ala Ile Ala Lys  Gln Pro Ile Asn Arg  Gly Gln Pro 
    1910                 1915                 1920             


Lys Pro  Ile Leu Gln Lys Gln  Ser Thr Phe Pro Gln  Ser Ser Lys 
    1925                 1930                 1935             


Asp Ile  Pro Asp Arg Gly Ala  Ala Thr Asp Glu Lys  Leu Gln Asn 
    1940                 1945                 1950             


Phe Ala  Ile Glu Asn Thr Pro  Val Cys Phe Ser His  Asn Ser Ser 
    1955                 1960                 1965             


Leu Ser  Ser Leu Ser Asp Ile  Asp Gln Glu Asn Asn  Asn Lys Glu 
    1970                 1975                 1980             


Asn Glu  Pro Ile Lys Glu Thr  Glu Pro Pro Asp Ser  Gln Gly Glu 
    1985                 1990                 1995             


Pro Ser  Lys Pro Gln Ala Ser  Gly Tyr Ala Pro Lys  Ser Phe His 
    2000                 2005                 2010             


Val Glu  Asp Thr Pro Val Cys  Phe Ser Arg Asn Ser  Ser Leu Ser 
    2015                 2020                 2025             


Ser Leu  Ser Ile Asp Ser Glu  Asp Asp Leu Leu Gln  Glu Cys Ile 
    2030                 2035                 2040             


Ser Ser  Ala Met Pro Lys Lys  Lys Lys Pro Ser Arg  Leu Lys Gly 
    2045                 2050                 2055             


Asp Asn  Glu Lys His Ser Pro  Arg Asn Met Gly Gly  Ile Leu Gly 
    2060                 2065                 2070             


Glu Asp  Leu Thr Leu Asp Leu  Lys Asp Ile Gln Arg  Pro Asp Ser 
    2075                 2080                 2085             


Glu His  Gly Leu Ser Pro Asp  Ser Glu Asn Phe Asp  Trp Lys Ala 
    2090                 2095                 2100             


Ile Gln  Glu Gly Ala Asn Ser  Ile Val Ser Ser Leu  His Gln Ala 
    2105                 2110                 2115             


Ala Ala  Ala Ala Cys Leu Ser  Arg Gln Ala Ser Ser  Asp Ser Asp 
    2120                 2125                 2130             


Ser Ile  Leu Ser Leu Lys Ser  Gly Ile Ser Leu Gly  Ser Pro Phe 
    2135                 2140                 2145             


His Leu  Thr Pro Asp Gln Glu  Glu Lys Pro Phe Thr  Ser Asn Lys 
    2150                 2155                 2160             


Gly Pro  Arg Ile Leu Lys Pro  Gly Glu Lys Ser Thr  Leu Glu Thr 
    2165                 2170                 2175             


Lys Lys  Ile Glu Ser Glu Ser  Lys Gly Ile Lys Gly  Gly Lys Lys 
    2180                 2185                 2190             


Val Tyr  Lys Ser Leu Ile Thr  Gly Lys Val Arg Ser  Asn Ser Glu 
    2195                 2200                 2205             


Ile Ser  Gly Gln Met Lys Gln  Pro Leu Gln Ala Asn  Met Pro Ser 
    2210                 2215                 2220             


Ile Ser  Arg Gly Arg Thr Met  Ile His Ile Pro Gly  Val Arg Asn 
    2225                 2230                 2235             


Ser Ser  Ser Ser Thr Ser Pro  Val Ser Lys Lys Gly  Pro Pro Leu 
    2240                 2245                 2250             


Lys Thr  Pro Ala Ser Lys Ser  Pro Ser Glu Gly Gln  Thr Ala Thr 
    2255                 2260                 2265             


Thr Ser  Pro Arg Gly Ala Lys  Pro Ser Val Lys Ser  Glu Leu Ser 
    2270                 2275                 2280             


Pro Val  Ala Arg Gln Thr Ser  Gln Ile Gly Gly Ser  Ser Lys Ala 
    2285                 2290                 2295             


Pro Ser  Arg Ser Gly Ser Arg  Asp Ser Thr Pro Ser  Arg Pro Ala 
    2300                 2305                 2310             


Gln Gln  Pro Leu Ser Arg Pro  Ile Gln Ser Pro Gly  Arg Asn Ser 
    2315                 2320                 2325             


Ile Ser  Pro Gly Arg Asn Gly  Ile Ser Pro Pro Asn  Lys Leu Ser 
    2330                 2335                 2340             


Gln Leu  Pro Arg Thr Ser Ser  Pro Ser Thr Ala Ser  Thr Lys Ser 
    2345                 2350                 2355             


Ser Gly  Ser Gly Lys Met Ser  Tyr Thr Ser Pro Gly  Arg Gln Met 
    2360                 2365                 2370             


Ser Gln  Gln Asn Leu Thr Lys  Gln Thr Gly Leu Ser  Lys Asn Ala 
    2375                 2380                 2385             


Ser Ser  Ile Pro Arg Ser Glu  Ser Ala Ser Lys Gly  Leu Asn Gln 
    2390                 2395                 2400             


Met Asn  Asn Gly Asn Gly Ala  Asn Lys Lys Val Glu  Leu Ser Arg 
    2405                 2410                 2415             


Met Ser  Ser Thr Lys Ser Ser  Gly Ser Glu Ser Asp  Arg Ser Glu 
    2420                 2425                 2430             


Arg Pro  Val Leu Val Arg Gln  Ser Thr Phe Ile Lys  Glu Ala Pro 
    2435                 2440                 2445             


Ser Pro  Thr Leu Arg Arg Lys  Leu Glu Glu Ser Ala  Ser Phe Glu 
    2450                 2455                 2460             


Ser Leu  Ser Pro Ser Ser Arg  Pro Ala Ser Pro Thr  Arg Ser Gln 
    2465                 2470                 2475             


Ala Gln  Thr Pro Val Leu Ser  Pro Ser Leu Pro Asp  Met Ser Leu 
    2480                 2485                 2490             


Ser Thr  His Ser Ser Val Gln  Ala Gly Gly Trp Arg  Lys Leu Pro 
    2495                 2500                 2505             


Pro Asn  Leu Ser Pro Thr Ile  Glu Tyr Asn Asp Gly  Arg Pro Ala 
    2510                 2515                 2520             


Lys Arg  His Asp Ile Ala Arg  Ser His Ser Glu Ser  Pro Ser Arg 
    2525                 2530                 2535             


Leu Pro  Ile Asn Arg Ser Gly  Thr Trp Lys Arg Glu  His Ser Lys 
    2540                 2545                 2550             


His Ser  Ser Ser Leu Pro Arg  Val Ser Thr Trp Arg  Arg Thr Gly 
    2555                 2560                 2565             


Ser Ser  Ser Ser Ile Leu Ser  Ala Ser Ser Glu Ser  Ser Glu Lys 
    2570                 2575                 2580             


Ala Lys  Ser Glu Asp Glu Lys  His Val Asn Ser Ile  Ser Gly Thr 
    2585                 2590                 2595             


Lys Gln  Ser Lys Glu Asn Gln  Val Ser Ala Lys Gly  Thr Trp Arg 
    2600                 2605                 2610             


Lys Ile  Lys Glu Asn Glu Phe  Ser Pro Thr Asn Ser  Thr Ser Gln 
    2615                 2620                 2625             


Thr Val  Ser Ser Gly Ala Thr  Asn Gly Ala Glu Ser  Lys Thr Leu 
    2630                 2635                 2640             


Ile Tyr  Gln Met Ala Pro Ala  Val Ser Lys Thr Glu  Asp Val Trp 
    2645                 2650                 2655             


Val Arg  Ile Glu Asp Cys Pro  Ile Asn Asn Pro Arg  Ser Gly Arg 
    2660                 2665                 2670             


Ser Pro  Thr Gly Asn Thr Pro  Pro Val Ile Asp Ser  Val Ser Glu 
    2675                 2680                 2685             


Lys Ala  Asn Pro Asn Ile Lys  Asp Ser Lys Asp Asn  Gln Ala Lys 
    2690                 2695                 2700             


Gln Asn  Val Gly Asn Gly Ser  Val Pro Met Arg Thr  Val Gly Leu 
    2705                 2710                 2715             


Glu Asn  Arg Leu Asn Ser Phe  Ile Gln Val Asp Ala  Pro Asp Gln 
    2720                 2725                 2730             


Lys Gly  Thr Glu Ile Lys Pro  Gly Gln Asn Asn Pro  Val Pro Val 
    2735                 2740                 2745             


Ser Glu  Thr Asn Glu Ser Ser  Ile Val Glu Arg Thr  Pro Phe Ser 
    2750                 2755                 2760             


Ser Ser  Ser Ser Ser Lys His  Ser Ser Pro Ser Gly  Thr Val Ala 
    2765                 2770                 2775             


Ala Arg  Val Thr Pro Phe Asn  Tyr Asn Pro Ser Pro  Arg Lys Ser 
    2780                 2785                 2790             


Ser Ala  Asp Ser Thr Ser Ala  Arg Pro Ser Gln Ile  Pro Thr Pro 
    2795                 2800                 2805             


Val Asn  Asn Asn Thr Lys Lys  Arg Asp Ser Lys Thr  Asp Ser Thr 
    2810                 2815                 2820             


Glu Ser  Ser Gly Thr Gln Ser  Pro Lys Arg His Ser  Gly Ser Tyr 
    2825                 2830                 2835             


Leu Val  Thr Ser Val 
    2840             


<210>  3304
<211>  930
<212>  PRT
<213>  homo sapiens

<400>  3304

Met Thr Gly Leu Glu Asp Gln Glu Phe Asp Phe Glu Phe Leu Phe Glu 
1               5                   10                  15      


Phe Asn Gln Arg Asp Glu Gly Ala Ala Ala Ala Ala Pro Glu His Tyr 
            20                  25                  30          


Gly Tyr Ala Ser Ser Asn Val Ser Pro Ala Leu Pro Leu Pro Thr Ala 
        35                  40                  45              


His Ser Thr Leu Pro Ala Pro Cys His Asn Leu Gln Thr Ser Thr Pro 
    50                  55                  60                  


Gly Ile Ile Pro Pro Ala Asp His Pro Ser Gly Tyr Gly Ala Ala Leu 
65                  70                  75                  80  


Asp Gly Gly Pro Ala Gly Tyr Phe Leu Ser Ser Gly His Thr Arg Pro 
                85                  90                  95      


Asp Gly Ala Pro Ala Leu Glu Ser Pro Arg Ile Glu Ile Thr Ser Cys 
            100                 105                 110         


Leu Gly Leu Tyr His Asn Asn Asn Gln Phe Phe His Asp Val Glu Val 
        115                 120                 125             


Glu Asp Val Leu Pro Ser Ser Lys Arg Ser Pro Ser Thr Ala Thr Leu 
    130                 135                 140                 


Ser Leu Pro Ser Leu Glu Ala Tyr Arg Asp Pro Ser Cys Leu Ser Pro 
145                 150                 155                 160 


Ala Ser Ser Leu Ser Ser Arg Ser Cys Asn Ser Glu Ala Ser Ser Tyr 
                165                 170                 175     


Glu Ser Asn Tyr Ser Tyr Pro Tyr Ala Ser Pro Gln Thr Ser Pro Trp 
            180                 185                 190         


Gln Ser Pro Cys Val Ser Pro Lys Thr Thr Asp Pro Glu Glu Gly Phe 
        195                 200                 205             


Pro Arg Gly Leu Gly Ala Cys Thr Leu Leu Gly Ser Pro Arg His Ser 
    210                 215                 220                 


Pro Ser Thr Ser Pro Arg Ala Ser Val Thr Glu Glu Ser Trp Leu Gly 
225                 230                 235                 240 


Ala Arg Ser Ser Arg Pro Ala Ser Pro Cys Asn Lys Arg Lys Tyr Ser 
                245                 250                 255     


Leu Asn Gly Arg Gln Pro Pro Tyr Ser Pro His His Ser Pro Thr Pro 
            260                 265                 270         


Ser Pro His Gly Ser Pro Arg Val Ser Val Thr Asp Asp Ser Trp Leu 
        275                 280                 285             


Gly Asn Thr Thr Gln Tyr Thr Ser Ser Ala Ile Val Ala Ala Ile Asn 
    290                 295                 300                 


Ala Leu Thr Thr Asp Ser Ser Leu Asp Leu Gly Asp Gly Val Pro Val 
305                 310                 315                 320 


Lys Ser Arg Lys Thr Thr Leu Glu Gln Pro Pro Ser Val Ala Leu Lys 
                325                 330                 335     


Val Glu Pro Val Gly Glu Asp Leu Gly Ser Pro Pro Pro Pro Ala Asp 
            340                 345                 350         


Phe Ala Pro Glu Asp Tyr Ser Ser Phe Gln His Ile Arg Lys Gly Gly 
        355                 360                 365             


Phe Cys Asp Gln Tyr Leu Ala Val Pro Gln His Pro Tyr Gln Trp Ala 
    370                 375                 380                 


Lys Pro Lys Pro Leu Ser Pro Thr Ser Tyr Met Ser Pro Thr Leu Pro 
385                 390                 395                 400 


Ala Leu Asp Trp Gln Leu Pro Ser His Ser Gly Pro Tyr Glu Leu Arg 
                405                 410                 415     


Ile Glu Val Gln Pro Lys Ser His His Arg Ala His Tyr Glu Thr Glu 
            420                 425                 430         


Gly Ser Arg Gly Ala Val Lys Ala Ser Ala Gly Gly His Pro Ile Val 
        435                 440                 445             


Gln Leu His Gly Tyr Leu Glu Asn Glu Pro Leu Met Leu Gln Leu Phe 
    450                 455                 460                 


Ile Gly Thr Ala Asp Asp Arg Leu Leu Arg Pro His Ala Phe Tyr Gln 
465                 470                 475                 480 


Val His Arg Ile Thr Gly Lys Thr Val Ser Thr Thr Ser His Glu Ala 
                485                 490                 495     


Ile Leu Ser Asn Thr Lys Val Leu Glu Ile Pro Leu Leu Pro Glu Asn 
            500                 505                 510         


Ser Met Arg Ala Val Ile Asp Cys Ala Gly Ile Leu Lys Leu Arg Asn 
        515                 520                 525             


Ser Asp Ile Glu Leu Arg Lys Gly Glu Thr Asp Ile Gly Arg Lys Asn 
    530                 535                 540                 


Thr Arg Val Arg Leu Val Phe Arg Val His Val Pro Gln Pro Ser Gly 
545                 550                 555                 560 


Arg Thr Leu Ser Leu Gln Val Ala Ser Asn Pro Ile Glu Cys Ser Gln 
                565                 570                 575     


Arg Ser Ala Gln Glu Leu Pro Leu Val Glu Lys Gln Ser Thr Asp Ser 
            580                 585                 590         


Tyr Pro Val Val Gly Gly Lys Lys Met Val Leu Ser Gly His Asn Phe 
        595                 600                 605             


Leu Gln Asp Ser Lys Val Ile Phe Val Glu Lys Ala Pro Asp Gly His 
    610                 615                 620                 


His Val Trp Glu Met Glu Ala Lys Thr Asp Arg Asp Leu Cys Lys Pro 
625                 630                 635                 640 


Asn Ser Leu Val Val Glu Ile Pro Pro Phe Arg Asn Gln Arg Ile Thr 
                645                 650                 655     


Ser Pro Val His Val Ser Phe Tyr Val Cys Asn Gly Lys Arg Lys Arg 
            660                 665                 670         


Ser Gln Tyr Gln Arg Phe Thr Tyr Leu Pro Ala Asn Val Pro Ile Ile 
        675                 680                 685             


Lys Thr Glu Pro Thr Asp Asp Tyr Glu Pro Ala Pro Thr Cys Gly Pro 
    690                 695                 700                 


Val Ser Gln Gly Leu Ser Pro Leu Pro Arg Pro Tyr Tyr Ser Gln Gln 
705                 710                 715                 720 


Leu Ala Met Pro Pro Asp Pro Ser Ser Cys Leu Val Ala Gly Phe Pro 
                725                 730                 735     


Pro Cys Pro Gln Arg Ser Thr Leu Met Pro Ala Ala Pro Gly Val Ser 
            740                 745                 750         


Pro Lys Leu His Asp Leu Ser Pro Ala Ala Tyr Thr Lys Gly Val Ala 
        755                 760                 765             


Ser Pro Gly His Cys His Leu Gly Leu Pro Gln Pro Ala Gly Glu Ala 
    770                 775                 780                 


Pro Ala Val Gln Asp Val Pro Arg Pro Val Ala Thr His Pro Gly Ser 
785                 790                 795                 800 


Pro Gly Gln Pro Pro Pro Ala Leu Leu Pro Gln Gln Val Ser Ala Pro 
                805                 810                 815     


Pro Ser Ser Ser Cys Pro Pro Gly Leu Glu His Ser Leu Cys Pro Ser 
            820                 825                 830         


Ser Pro Ser Pro Pro Leu Pro Pro Ala Thr Gln Glu Pro Thr Cys Leu 
        835                 840                 845             


Gln Pro Cys Ser Pro Ala Cys Pro Pro Ala Thr Gly Arg Pro Gln His 
    850                 855                 860                 


Leu Pro Ser Thr Val Arg Arg Asp Glu Ser Pro Thr Ala Gly Pro Arg 
865                 870                 875                 880 


Leu Leu Pro Glu Val His Glu Asp Gly Ser Pro Asn Leu Ala Pro Ile 
                885                 890                 895     


Pro Val Thr Val Lys Arg Glu Pro Glu Glu Leu Asp Gln Leu Tyr Leu 
            900                 905                 910         


Asp Asp Val Asn Glu Ile Ile Arg Asn Asp Leu Ser Ser Thr Ser Thr 
        915                 920                 925             


His Ser 
    930 


<210>  3305
<211>  461
<212>  PRT
<213>  homo sapiens

<400>  3305

Met Ser Ser Pro Thr Thr Ser Ser Leu Asp Thr Pro Leu Pro Gly Asn 
1               5                   10                  15      


Gly Pro Pro Gln Pro Gly Ala Pro Ser Ser Ser Pro Thr Val Lys Glu 
            20                  25                  30          


Glu Gly Pro Glu Pro Trp Pro Gly Gly Pro Asp Pro Asp Val Pro Gly 
        35                  40                  45              


Thr Asp Glu Ala Ser Ser Ala Cys Ser Thr Asp Trp Val Ile Pro Asp 
    50                  55                  60                  


Pro Glu Glu Glu Pro Glu Arg Lys Arg Lys Lys Gly Pro Ala Pro Lys 
65                  70                  75                  80  


Met Leu Gly His Glu Leu Cys Arg Val Cys Gly Asp Lys Ala Ser Gly 
                85                  90                  95      


Phe His Tyr Asn Val Leu Ser Cys Glu Gly Cys Lys Gly Phe Phe Arg 
            100                 105                 110         


Arg Ser Val Val Arg Gly Gly Ala Arg Arg Tyr Ala Cys Arg Gly Gly 
        115                 120                 125             


Gly Thr Cys Gln Met Asp Ala Phe Met Arg Arg Lys Cys Gln Gln Cys 
    130                 135                 140                 


Arg Leu Arg Lys Cys Lys Glu Ala Gly Met Arg Glu Gln Cys Val Leu 
145                 150                 155                 160 


Ser Glu Glu Gln Ile Arg Lys Lys Lys Ile Arg Lys Gln Gln Gln Gln 
                165                 170                 175     


Glu Ser Gln Ser Gln Ser Gln Ser Pro Val Gly Pro Gln Gly Ser Ser 
            180                 185                 190         


Ser Ser Ala Ser Gly Pro Gly Ala Ser Pro Gly Gly Ser Glu Ala Gly 
        195                 200                 205             


Ser Gln Gly Ser Gly Glu Gly Glu Gly Val Gln Leu Thr Ala Ala Gln 
    210                 215                 220                 


Glu Leu Met Ile Gln Gln Leu Val Ala Ala Gln Leu Gln Cys Asn Lys 
225                 230                 235                 240 


Arg Ser Phe Ser Asp Gln Pro Lys Val Thr Pro Trp Pro Leu Gly Ala 
                245                 250                 255     


Asp Pro Gln Ser Arg Asp Ala Arg Gln Gln Arg Phe Ala His Phe Thr 
            260                 265                 270         


Glu Leu Ala Ile Ile Ser Val Gln Glu Ile Val Asp Phe Ala Lys Gln 
        275                 280                 285             


Val Pro Gly Phe Leu Gln Leu Gly Arg Glu Asp Gln Ile Ala Leu Leu 
    290                 295                 300                 


Lys Ala Ser Thr Ile Glu Ile Met Leu Leu Glu Thr Ala Arg Arg Tyr 
305                 310                 315                 320 


Asn His Glu Thr Glu Cys Ile Thr Phe Leu Lys Asp Phe Thr Tyr Ser 
                325                 330                 335     


Lys Asp Asp Phe His Arg Ala Gly Leu Gln Val Glu Phe Ile Asn Pro 
            340                 345                 350         


Ile Phe Glu Phe Ser Arg Ala Met Arg Arg Leu Gly Leu Asp Asp Ala 
        355                 360                 365             


Glu Tyr Ala Leu Leu Ile Ala Ile Asn Ile Phe Ser Ala Asp Arg Pro 
    370                 375                 380                 


Asn Val Gln Glu Pro Gly Arg Val Glu Ala Leu Gln Gln Pro Tyr Val 
385                 390                 395                 400 


Glu Ala Leu Leu Ser Tyr Thr Arg Ile Lys Arg Pro Gln Asp Gln Leu 
                405                 410                 415     


Arg Phe Pro Arg Met Leu Met Lys Leu Val Ser Leu Arg Thr Leu Ser 
            420                 425                 430         


Ser Val His Ser Glu Gln Val Phe Ala Leu Arg Leu Gln Asp Lys Lys 
        435                 440                 445             


Leu Pro Pro Leu Leu Ser Glu Ile Trp Asp Val His Glu 
    450                 455                 460     


<210>  3306
<211>  485
<212>  PRT
<213>  homo sapiens

<400>  3306

Met Gly Gly Cys Arg Lys Phe Gly Glu Arg Pro Pro Pro Lys Arg Leu 
1               5                   10                  15      


Thr Arg Glu Ala Met Arg Asn Tyr Leu Lys Glu Arg Gly Asp Gln Thr 
            20                  25                  30          


Val Leu Ile Leu His Ala Lys Val Ala Gln Lys Ser Tyr Gly Asn Glu 
        35                  40                  45              


Lys Arg Phe Phe Cys Pro Pro Pro Cys Val Tyr Leu Met Gly Ser Gly 
    50                  55                  60                  


Trp Lys Lys Lys Lys Glu Gln Met Glu Arg Asp Gly Cys Ser Glu Gln 
65                  70                  75                  80  


Glu Ser Gln Pro Cys Ala Phe Ile Gly Ile Gly Asn Ser Asp Gln Glu 
                85                  90                  95      


Met Gln Gln Leu Asn Leu Glu Gly Lys Asn Tyr Cys Thr Ala Lys Thr 
            100                 105                 110         


Leu Tyr Ile Ser Asp Ser Asp Lys Arg Lys His Phe Met Leu Ser Val 
        115                 120                 125             


Lys Met Phe Tyr Gly Asn Ser Asp Asp Ile Gly Val Phe Leu Ser Lys 
    130                 135                 140                 


Arg Ile Lys Val Ile Ser Lys Pro Ser Lys Lys Lys Gln Ser Leu Lys 
145                 150                 155                 160 


Asn Ala Asp Leu Cys Ile Ala Ser Gly Thr Lys Val Ala Leu Phe Asn 
                165                 170                 175     


Arg Leu Arg Ser Gln Thr Val Ser Thr Arg Tyr Leu His Val Glu Gly 
            180                 185                 190         


Gly Asn Phe His Ala Ser Ser Gln Gln Trp Gly Ala Phe Phe Ile His 
        195                 200                 205             


Leu Leu Asp Asp Asp Glu Ser Glu Gly Glu Glu Phe Thr Val Arg Asp 
    210                 215                 220                 


Gly Tyr Ile His Tyr Gly Gln Thr Val Lys Leu Val Cys Ser Val Thr 
225                 230                 235                 240 


Gly Met Ala Leu Pro Arg Leu Ile Ile Arg Lys Val Asp Lys Gln Thr 
                245                 250                 255     


Ala Leu Leu Asp Ala Asp Asp Pro Val Ser Gln Leu His Lys Cys Ala 
            260                 265                 270         


Phe Tyr Leu Lys Asp Thr Glu Arg Met Tyr Leu Cys Leu Ser Gln Glu 
        275                 280                 285             


Arg Ile Ile Gln Phe Gln Ala Thr Pro Cys Pro Lys Glu Pro Asn Lys 
    290                 295                 300                 


Glu Met Ile Asn Asp Gly Ala Ser Trp Thr Ile Ile Ser Thr Asp Lys 
305                 310                 315                 320 


Ala Glu Tyr Thr Phe Tyr Glu Gly Met Gly Pro Val Leu Ala Pro Val 
                325                 330                 335     


Thr Pro Val Pro Val Val Glu Ser Leu Gln Leu Asn Gly Gly Gly Asp 
            340                 345                 350         


Val Ala Met Leu Glu Leu Thr Gly Gln Asn Phe Thr Pro Asn Leu Arg 
        355                 360                 365             


Val Trp Phe Gly Asp Val Glu Ala Glu Thr Met Tyr Arg Cys Gly Glu 
    370                 375                 380                 


Ser Met Leu Cys Val Val Pro Asp Ile Ser Ala Phe Arg Glu Gly Trp 
385                 390                 395                 400 


Arg Trp Val Arg Gln Pro Val Gln Val Pro Val Thr Leu Val Arg Asn 
                405                 410                 415     


Asp Gly Ile Ile Tyr Ser Thr Ser Leu Thr Phe Thr Tyr Thr Pro Glu 
            420                 425                 430         


Pro Gly Pro Arg Pro His Cys Ser Ala Ala Gly Ala Ile Leu Arg Ala 
        435                 440                 445             


Asn Ser Ser Gln Val Pro Pro Asn Glu Ser Asn Thr Asn Ser Glu Gly 
    450                 455                 460                 


Ser Tyr Thr Asn Ala Ser Thr Asn Ser Thr Ser Val Thr Ser Ser Thr 
465                 470                 475                 480 


Ala Thr Val Val Ser 
                485 


<210>  3307
<211>  500
<212>  PRT
<213>  homo sapiens

<400>  3307

Met Asp His Thr Glu Gly Ser Pro Ala Glu Glu Pro Pro Ala His Ala 
1               5                   10                  15      


Pro Ser Pro Gly Lys Phe Gly Glu Arg Pro Pro Pro Lys Arg Leu Thr 
            20                  25                  30          


Arg Glu Ala Met Arg Asn Tyr Leu Lys Glu Arg Gly Asp Gln Thr Val 
        35                  40                  45              


Leu Ile Leu His Ala Lys Val Ala Gln Lys Ser Tyr Gly Asn Glu Lys 
    50                  55                  60                  


Arg Phe Phe Cys Pro Pro Pro Cys Val Tyr Leu Met Gly Ser Gly Trp 
65                  70                  75                  80  


Lys Lys Lys Lys Glu Gln Met Glu Arg Asp Gly Cys Ser Glu Gln Glu 
                85                  90                  95      


Ser Gln Pro Cys Ala Phe Ile Gly Ile Gly Asn Ser Asp Gln Glu Met 
            100                 105                 110         


Gln Gln Leu Asn Leu Glu Gly Lys Asn Tyr Cys Thr Ala Lys Thr Leu 
        115                 120                 125             


Tyr Ile Ser Asp Ser Asp Lys Arg Lys His Phe Met Leu Ser Val Lys 
    130                 135                 140                 


Met Phe Tyr Gly Asn Ser Asp Asp Ile Gly Val Phe Leu Ser Lys Arg 
145                 150                 155                 160 


Ile Lys Val Ile Ser Lys Pro Ser Lys Lys Lys Gln Ser Leu Lys Asn 
                165                 170                 175     


Ala Asp Leu Cys Ile Ala Ser Gly Thr Lys Val Ala Leu Phe Asn Arg 
            180                 185                 190         


Leu Arg Ser Gln Thr Val Ser Thr Arg Tyr Leu His Val Glu Gly Gly 
        195                 200                 205             


Asn Phe His Ala Ser Ser Gln Gln Trp Gly Ala Phe Phe Ile His Leu 
    210                 215                 220                 


Leu Asp Asp Asp Glu Ser Glu Gly Glu Glu Phe Thr Val Arg Asp Gly 
225                 230                 235                 240 


Tyr Ile His Tyr Gly Gln Thr Val Lys Leu Val Cys Ser Val Thr Gly 
                245                 250                 255     


Met Ala Leu Pro Arg Leu Ile Ile Arg Lys Val Asp Lys Gln Thr Ala 
            260                 265                 270         


Leu Leu Asp Ala Asp Asp Pro Val Ser Gln Leu His Lys Cys Ala Phe 
        275                 280                 285             


Tyr Leu Lys Asp Thr Glu Arg Met Tyr Leu Cys Leu Ser Gln Glu Arg 
    290                 295                 300                 


Ile Ile Gln Phe Gln Ala Thr Pro Cys Pro Lys Glu Pro Asn Lys Glu 
305                 310                 315                 320 


Met Ile Asn Asp Gly Ala Ser Trp Thr Ile Ile Ser Thr Asp Lys Ala 
                325                 330                 335     


Glu Tyr Thr Phe Tyr Glu Gly Met Gly Pro Val Leu Ala Pro Val Thr 
            340                 345                 350         


Pro Val Pro Val Val Glu Ser Leu Gln Leu Asn Gly Gly Gly Asp Val 
        355                 360                 365             


Ala Met Leu Glu Leu Thr Gly Gln Asn Phe Thr Pro Asn Leu Arg Val 
    370                 375                 380                 


Trp Phe Gly Asp Val Glu Ala Glu Thr Met Tyr Arg Cys Gly Glu Ser 
385                 390                 395                 400 


Met Leu Cys Val Val Pro Asp Ile Ser Ala Phe Arg Glu Gly Trp Arg 
                405                 410                 415     


Trp Val Arg Gln Pro Val Gln Val Pro Val Thr Leu Val Arg Asn Asp 
            420                 425                 430         


Gly Ile Ile Tyr Ser Thr Ser Leu Thr Phe Thr Tyr Thr Pro Glu Pro 
        435                 440                 445             


Gly Pro Arg Pro His Cys Ser Ala Ala Gly Ala Ile Leu Arg Ala Asn 
    450                 455                 460                 


Ser Ser Gln Val Pro Pro Asn Glu Ser Asn Thr Asn Ser Glu Gly Ser 
465                 470                 475                 480 


Tyr Thr Asn Ala Ser Thr Asn Ser Thr Ser Val Thr Ser Ser Thr Ala 
                485                 490                 495     


Thr Val Val Ser 
            500 


<210>  3308
<211>  1253
<212>  PRT
<213>  homo sapiens

<400>  3308

Met Leu Ser Trp Arg Leu Gln Thr Gly Pro Glu Lys Ala Glu Leu Gln 
1               5                   10                  15      


Glu Leu Asn Ala Arg Leu Tyr Asp Tyr Val Cys Arg Val Arg Glu Leu 
            20                  25                  30          


Glu Arg Glu Asn Leu Leu Leu Glu Glu Glu Leu Arg Gly Arg Arg Gly 
        35                  40                  45              


Arg Glu Gly Leu Trp Ala Glu Gly Gln Ala Arg Cys Ala Glu Glu Ala 
    50                  55                  60                  


Arg Ser Leu Arg Gln Gln Leu Asp Glu Leu Ser Trp Ala Thr Ala Leu 
65                  70                  75                  80  


Ala Glu Gly Glu Arg Asp Ala Leu Arg Arg Glu Leu Arg Glu Leu Gln 
                85                  90                  95      


Arg Leu Asp Ala Glu Glu Arg Ala Ala Arg Gly Arg Leu Asp Ala Glu 
            100                 105                 110         


Leu Gly Ala Gln Gln Arg Glu Leu Gln Glu Ala Leu Gly Ala Arg Ala 
        115                 120                 125             


Ala Leu Glu Ala Leu Leu Gly Arg Leu Gln Ala Glu Arg Arg Gly Leu 
    130                 135                 140                 


Asp Ala Ala His Glu Arg Asp Val Arg Glu Leu Arg Ala Arg Ala Ala 
145                 150                 155                 160 


Ser Leu Thr Met His Phe Arg Ala Arg Ala Thr Gly Pro Ala Ala Pro 
                165                 170                 175     


Pro Pro Arg Leu Arg Glu Val His Asp Ser Tyr Ala Leu Leu Val Ala 
            180                 185                 190         


Glu Ser Trp Arg Glu Thr Val Gln Leu Tyr Glu Asp Glu Val Arg Glu 
        195                 200                 205             


Leu Glu Glu Ala Leu Arg Arg Gly Gln Glu Ser Arg Leu Gln Ala Glu 
    210                 215                 220                 


Glu Glu Thr Arg Leu Cys Ala Gln Glu Ala Glu Ala Leu Arg Arg Glu 
225                 230                 235                 240 


Ala Leu Gly Leu Glu Gln Leu Arg Ala Arg Leu Glu Asp Ala Leu Leu 
                245                 250                 255     


Arg Met Arg Glu Glu Tyr Gly Ile Gln Ala Glu Glu Arg Gln Arg Val 
            260                 265                 270         


Ile Asp Cys Leu Glu Asp Glu Lys Ala Thr Leu Thr Leu Ala Met Ala 
        275                 280                 285             


Asp Trp Leu Arg Asp Tyr Gln Asp Leu Leu Gln Val Lys Thr Gly Leu 
    290                 295                 300                 


Ser Leu Glu Val Ala Thr Tyr Arg Ala Leu Leu Glu Gly Glu Ser Asn 
305                 310                 315                 320 


Pro Glu Ile Val Ile Trp Ala Glu His Val Glu Asn Met Pro Ser Glu 
                325                 330                 335     


Phe Arg Asn Lys Ser Tyr His Tyr Thr Asp Ser Leu Leu Gln Arg Glu 
            340                 345                 350         


Asn Glu Arg Asn Leu Phe Ser Arg Gln Lys Ala Pro Leu Ala Ser Phe 
        355                 360                 365             


Asn His Ser Ser Ala Leu Tyr Ser Asn Leu Ser Gly His Arg Gly Ser 
    370                 375                 380                 


Gln Thr Gly Thr Ser Ile Gly Gly Asp Ala Arg Arg Gly Phe Leu Gly 
385                 390                 395                 400 


Ser Gly Tyr Ser Ser Ser Ala Thr Thr Gln Gln Glu Asn Ser Tyr Gly 
                405                 410                 415     


Lys Ala Val Ser Ser Gln Thr Asn Val Arg Thr Phe Ser Pro Thr Tyr 
            420                 425                 430         


Gly Leu Leu Arg Asn Thr Glu Ala Gln Val Lys Thr Phe Pro Asp Arg 
        435                 440                 445             


Pro Lys Ala Gly Asp Thr Arg Glu Val Pro Val Tyr Ile Gly Glu Asp 
    450                 455                 460                 


Ser Thr Ile Ala Arg Glu Ser Tyr Arg Asp Arg Arg Asp Lys Val Ala 
465                 470                 475                 480 


Ala Gly Ala Ser Glu Ser Thr Arg Ser Asn Glu Arg Thr Val Ile Leu 
                485                 490                 495     


Gly Lys Lys Thr Glu Val Lys Ala Thr Arg Glu Gln Glu Arg Asn Arg 
            500                 505                 510         


Pro Glu Thr Ile Arg Thr Lys Pro Glu Glu Lys Met Phe Asp Ser Lys 
        515                 520                 525             


Glu Lys Ala Ser Glu Glu Arg Asn Leu Arg Trp Glu Glu Leu Thr Lys 
    530                 535                 540                 


Leu Asp Lys Glu Ala Arg Gln Arg Glu Ser Gln Gln Met Lys Glu Lys 
545                 550                 555                 560 


Ala Lys Glu Lys Asp Ser Pro Lys Glu Lys Ser Val Arg Glu Arg Glu 
                565                 570                 575     


Val Pro Ile Ser Leu Glu Val Ser Gln Asp Arg Arg Ala Glu Val Ser 
            580                 585                 590         


Pro Lys Gly Leu Gln Thr Pro Val Lys Asp Ala Gly Gly Gly Thr Gly 
        595                 600                 605             


Arg Glu Ala Glu Ala Arg Glu Leu Arg Phe Arg Leu Gly Thr Ser Asp 
    610                 615                 620                 


Ala Thr Gly Ser Leu Gln Gly Asp Ser Met Thr Glu Thr Val Ala Glu 
625                 630                 635                 640 


Asn Ile Val Thr Ser Ile Leu Lys Gln Phe Thr Gln Ser Pro Glu Thr 
                645                 650                 655     


Glu Ala Ser Ala Asp Ser Phe Pro Asp Thr Lys Val Thr Tyr Val Asp 
            660                 665                 670         


Arg Lys Glu Leu Pro Gly Glu Arg Lys Thr Lys Thr Glu Ile Val Val 
        675                 680                 685             


Glu Ser Lys Leu Thr Glu Asp Val Asp Val Ser Asp Glu Ala Gly Leu 
    690                 695                 700                 


Asp Tyr Leu Leu Ser Lys Asp Ile Lys Glu Val Gly Leu Lys Gly Lys 
705                 710                 715                 720 


Ser Ala Glu Gln Met Ile Gly Asp Ile Ile Asn Leu Gly Leu Lys Gly 
                725                 730                 735     


Arg Glu Gly Arg Ala Lys Val Val Asn Val Glu Ile Val Glu Glu Pro 
            740                 745                 750         


Val Ser Tyr Val Ser Gly Glu Lys Pro Glu Glu Phe Ser Val Pro Phe 
        755                 760                 765             


Lys Val Glu Glu Val Glu Asp Val Ser Pro Gly Pro Trp Gly Leu Val 
    770                 775                 780                 


Lys Glu Glu Glu Gly Tyr Gly Glu Ser Asp Val Thr Phe Ser Val Asn 
785                 790                 795                 800 


Gln His Arg Arg Thr Lys Gln Pro Gln Glu Asn Thr Thr His Val Glu 
                805                 810                 815     


Glu Val Thr Glu Ala Gly Asp Ser Glu Gly Glu Gln Ser Tyr Phe Val 
            820                 825                 830         


Ser Thr Pro Asp Glu His Pro Gly Gly His Asp Arg Asp Asp Gly Ser 
        835                 840                 845             


Val Tyr Gly Gln Ile His Ile Glu Glu Glu Ser Thr Ile Arg Tyr Ser 
    850                 855                 860                 


Trp Gln Asp Glu Ile Val Gln Gly Thr Arg Arg Arg Thr Gln Lys Asp 
865                 870                 875                 880 


Gly Ala Val Gly Glu Lys Val Val Lys Pro Leu Asp Val Pro Ala Pro 
                885                 890                 895     


Ser Leu Glu Gly Asp Leu Gly Ser Thr His Trp Lys Glu Gln Ala Arg 
            900                 905                 910         


Ser Gly Glu Phe His Ala Glu Pro Thr Val Ile Glu Lys Glu Ile Lys 
        915                 920                 925             


Ile Pro His Glu Phe His Thr Ser Met Lys Gly Ile Ser Ser Lys Glu 
    930                 935                 940                 


Pro Arg Gln Gln Leu Val Glu Val Ile Gly Gln Leu Glu Glu Thr Leu 
945                 950                 955                 960 


Pro Glu Arg Met Arg Glu Glu Leu Ser Ala Leu Thr Arg Glu Gly Gln 
                965                 970                 975     


Gly Gly Pro Gly Ser Val Ser Val Asp Val Lys Lys Val Gln Gly Ala 
            980                 985                 990         


Gly Gly Ser Ser Val Thr Leu Val  Ala Glu Val Asn Val  Ser Gln Thr 
        995                 1000                 1005             


Val Asp  Ala Asp Arg Leu Asp  Leu Glu Glu Leu Ser  Lys Asp Glu 
    1010                 1015                 1020             


Ala Ser  Glu Met Glu Lys Ala  Val Glu Ser Val Val  Arg Glu Ser 
    1025                 1030                 1035             


Leu Ser  Arg Gln Arg Ser Pro  Ala Pro Gly Ser Pro  Asp Glu Glu 
    1040                 1045                 1050             


Gly Gly  Ala Glu Ala Pro Ala  Ala Gly Ile Arg Phe  Arg Arg Trp 
    1055                 1060                 1065             


Ala Thr  Arg Glu Leu Tyr Ile  Pro Ser Gly Glu Ser  Glu Val Ala 
    1070                 1075                 1080             


Gly Gly  Ala Ser His Ser Ser  Gly Gln Arg Thr Pro  Gln Gly Pro 
    1085                 1090                 1095             


Val Ser  Ala Thr Val Glu Val  Ser Ser Pro Thr Gly  Phe Ala Gln 
    1100                 1105                 1110             


Ser Gln  Val Leu Glu Asp Val  Ser Gln Ala Ala Arg  His Ile Lys 
    1115                 1120                 1125             


Leu Gly  Pro Ser Glu Val Trp  Arg Thr Glu Arg Met  Ser Tyr Glu 
    1130                 1135                 1140             


Gly Pro  Thr Ala Glu Val Val  Glu Met Asp Val Ser  Asn Val Glu 
    1145                 1150                 1155             


Ala Ile  Arg Ser Arg Thr Gln  Glu Ala Gly Ala Leu  Gly Val Ser 
    1160                 1165                 1170             


Asp Arg  Gly Ser Trp Arg Asp  Ala Asp Ser Arg Asn  Asp Gln Ala 
    1175                 1180                 1185             


Val Gly  Val Ser Phe Lys Ala  Ser Ala Gly Glu Gly  Asp Gln Ala 
    1190                 1195                 1200             


His Arg  Glu Gln Gly Lys Glu  Gln Ala Met Phe Asp  Lys Lys Val 
    1205                 1210                 1215             


Gln Leu  Gln Arg Met Val Asp  Gln Arg Ser Val Ile  Ser Asp Glu 
    1220                 1225                 1230             


Lys Lys  Val Ala Leu Leu Tyr  Leu Asp Asn Glu Glu  Glu Glu Asn 
    1235                 1240                 1245             


Asp Gly  His Trp Phe 
    1250             


<210>  3309
<211>  265
<212>  PRT
<213>  homo sapiens

<400>  3309

Met Cys Met Val Ile Phe Ala Pro Leu Phe Ala Ile Phe Ala Phe Ala 
1               5                   10                  15      


Thr Cys Gly Gly Tyr Ser Gly Gly Leu Arg Leu Ser Val Asp Cys Val 
            20                  25                  30          


Asn Lys Thr Glu Ser Asn Leu Ser Ile Asp Ile Ala Phe Ala Tyr Pro 
        35                  40                  45              


Phe Arg Leu His Gln Val Thr Phe Glu Val Pro Thr Cys Glu Gly Lys 
    50                  55                  60                  


Glu Arg Gln Lys Leu Ala Leu Ile Gly Asp Ser Ser Ser Ser Ala Glu 
65                  70                  75                  80  


Phe Phe Val Thr Val Ala Val Phe Ala Phe Leu Tyr Ser Leu Ala Ala 
                85                  90                  95      


Thr Val Val Tyr Ile Phe Phe Gln Asn Lys Tyr Arg Glu Asn Asn Arg 
            100                 105                 110         


Gly Pro Leu Ile Asp Phe Ile Val Thr Val Val Phe Ser Phe Leu Trp 
        115                 120                 125             


Leu Val Gly Ser Ser Ala Trp Ala Lys Gly Leu Ser Asp Val Lys Val 
    130                 135                 140                 


Ala Thr Asp Pro Lys Glu Val Leu Leu Leu Met Ser Ala Cys Lys Gln 
145                 150                 155                 160 


Pro Ser Asn Lys Cys Met Ala Ile His Ser Pro Val Met Ser Ser Leu 
                165                 170                 175     


Asn Thr Ser Val Val Phe Gly Phe Leu Asn Phe Ile Leu Trp Ala Gly 
            180                 185                 190         


Asn Ile Trp Phe Val Phe Lys Glu Thr Gly Trp His Ser Ser Gly Gln 
        195                 200                 205             


Arg Tyr Leu Ser Asp Pro Met Glu Lys His Ser Ser Ser Tyr Asn Gln 
    210                 215                 220                 


Gly Gly Tyr Asn Gln Asp Ser Tyr Gly Ser Ser Ser Gly Tyr Ser Gln 
225                 230                 235                 240 


Gln Ala Ser Leu Gly Pro Thr Ser Asp Glu Phe Gly Gln Gln Pro Thr 
                245                 250                 255     


Gly Pro Thr Ser Phe Thr Asn Gln Ile 
            260                 265 


<210>  3310
<211>  1199
<212>  PRT
<213>  homo sapiens

<400>  3310

Met Pro Leu Thr Gly Val Glu Pro Ala Arg Met Asn Arg Lys Lys Gly 
1               5                   10                  15      


Asp Lys Gly Phe Glu Ser Pro Arg Pro Tyr Lys Leu Thr His Gln Val 
            20                  25                  30          


Val Cys Ile Asn Asn Ile Asn Phe Gln Arg Lys Ser Val Val Gly Phe 
        35                  40                  45              


Val Glu Leu Thr Ile Phe Pro Thr Val Ala Asn Leu Asn Arg Ile Lys 
    50                  55                  60                  


Leu Asn Ser Lys Gln Cys Arg Ile Tyr Arg Val Arg Ile Asn Asp Leu 
65                  70                  75                  80  


Glu Ala Ala Phe Ile Tyr Asn Asp Pro Thr Leu Glu Val Cys His Ser 
                85                  90                  95      


Glu Ser Lys Gln Arg Asn Leu Asn Tyr Phe Ser Asn Ala Tyr Ala Ala 
            100                 105                 110         


Ala Val Ser Ala Val Asp Pro Asp Ala Gly Asn Gly Glu Leu Cys Ile 
        115                 120                 125             


Lys Val Pro Ser Glu Leu Trp Lys His Val Asp Glu Leu Lys Val Leu 
    130                 135                 140                 


Lys Ile His Ile Asn Phe Ser Leu Asp Gln Pro Lys Gly Gly Leu His 
145                 150                 155                 160 


Phe Val Val Pro Ser Val Glu Gly Ser Met Ala Glu Arg Gly Ala His 
                165                 170                 175     


Val Phe Ser Cys Gly Tyr Gln Asn Ser Thr Arg Phe Trp Phe Pro Cys 
            180                 185                 190         


Val Asp Ser Tyr Ser Glu Leu Cys Thr Trp Lys Leu Glu Phe Thr Val 
        195                 200                 205             


Asp Ala Ala Met Val Ala Val Ser Asn Gly Asp Leu Val Glu Thr Val 
    210                 215                 220                 


Tyr Thr His Asp Met Arg Lys Lys Thr Phe His Tyr Met Leu Thr Ile 
225                 230                 235                 240 


Pro Thr Ala Ala Ser Asn Ile Ser Leu Ala Ile Gly Pro Phe Glu Ile 
                245                 250                 255     


Leu Val Asp Pro Tyr Met His Glu Val Thr His Phe Cys Leu Pro Gln 
            260                 265                 270         


Leu Leu Pro Leu Leu Lys His Thr Thr Ser Tyr Leu His Glu Val Phe 
        275                 280                 285             


Glu Phe Tyr Glu Glu Ile Leu Thr Cys Arg Tyr Pro Tyr Ser Cys Phe 
    290                 295                 300                 


Lys Thr Val Phe Ile Asp Glu Ala Tyr Val Glu Val Ala Ala Tyr Ala 
305                 310                 315                 320 


Ser Met Ser Ile Phe Ser Thr Asn Leu Leu His Ser Ala Met Ile Ile 
                325                 330                 335     


Asp Glu Thr Pro Leu Thr Arg Arg Cys Leu Ala Gln Ser Leu Ala Gln 
            340                 345                 350         


Gln Phe Phe Gly Cys Phe Ile Ser Arg Met Ser Trp Ser Asp Glu Trp 
        355                 360                 365             


Val Leu Lys Gly Ile Ser Gly Tyr Ile Tyr Gly Leu Trp Met Lys Lys 
    370                 375                 380                 


Thr Phe Gly Val Asn Glu Tyr Arg His Trp Ile Lys Glu Glu Leu Asp 
385                 390                 395                 400 


Lys Ile Val Ala Tyr Glu Leu Lys Thr Gly Gly Val Leu Leu His Pro 
                405                 410                 415     


Ile Phe Gly Gly Gly Lys Glu Lys Asp Asn Pro Ala Ser His Leu His 
            420                 425                 430         


Phe Ser Ile Lys His Pro His Thr Leu Ser Trp Glu Tyr Tyr Thr Met 
        435                 440                 445             


Phe Gln Cys Lys Ala His Leu Val Met Arg Leu Ile Glu Asn Arg Ile 
    450                 455                 460                 


Ser Met Glu Phe Met Leu Gln Val Phe Asn Lys Leu Leu Ser Leu Ala 
465                 470                 475                 480 


Ser Thr Ala Ser Ser Gln Lys Phe Gln Ser His Met Trp Ser Gln Met 
                485                 490                 495     


Leu Val Ser Thr Ser Gly Phe Leu Lys Ser Ile Ser Asn Val Ser Gly 
            500                 505                 510         


Lys Asp Ile Gln Pro Leu Ile Lys Gln Trp Val Asp Gln Ser Gly Val 
        515                 520                 525             


Val Lys Phe Tyr Gly Ser Phe Ala Phe Asn Arg Lys Arg Asn Val Leu 
    530                 535                 540                 


Glu Leu Glu Ile Lys Gln Asp Tyr Thr Ser Pro Gly Thr Gln Lys Tyr 
545                 550                 555                 560 


Val Gly Pro Leu Lys Val Thr Val Gln Glu Leu Asp Gly Ser Phe Asn 
                565                 570                 575     


His Thr Leu Gln Ile Glu Glu Asn Ser Leu Lys His Asp Ile Pro Cys 
            580                 585                 590         


His Ser Lys Ser Arg Arg Asn Lys Lys Lys Lys Ile Pro Leu Met Asn 
        595                 600                 605             


Gly Glu Glu Val Asp Met Asp Leu Ser Ala Met Asp Ala Asp Ser Pro 
    610                 615                 620                 


Leu Leu Trp Ile Arg Ile Asp Pro Asp Met Ser Val Leu Arg Lys Val 
625                 630                 635                 640 


Glu Phe Glu Gln Ala Asp Phe Met Trp Gln Tyr Gln Leu Arg Tyr Glu 
                645                 650                 655     


Arg Asp Val Val Ala Gln Gln Glu Ser Ile Leu Ala Leu Glu Lys Phe 
            660                 665                 670         


Pro Thr Pro Ala Ser Arg Leu Ala Leu Thr Asp Ile Leu Glu Gln Glu 
        675                 680                 685             


Gln Cys Phe Tyr Arg Val Arg Met Ser Ala Cys Phe Cys Leu Ala Lys 
    690                 695                 700                 


Ile Ala Asn Ser Met Val Ser Thr Trp Thr Gly Pro Pro Ala Met Lys 
705                 710                 715                 720 


Ser Leu Phe Thr Arg Met Phe Cys Cys Lys Ser Cys Pro Asn Ile Val 
                725                 730                 735     


Lys Thr Asn Asn Phe Met Ser Phe Gln Ser Tyr Phe Leu Gln Lys Thr 
            740                 745                 750         


Met Pro Val Ala Met Ala Leu Leu Arg Asp Val His Asn Leu Cys Pro 
        755                 760                 765             


Lys Glu Val Leu Thr Phe Ile Leu Asp Leu Ile Lys Tyr Asn Asp Asn 
    770                 775                 780                 


Arg Lys Asn Lys Phe Ser Asp Asn Tyr Tyr Arg Ala Glu Met Ile Asp 
785                 790                 795                 800 


Ala Leu Ala Asn Ser Val Thr Pro Ala Val Ser Val Asn Asn Glu Val 
                805                 810                 815     


Arg Thr Leu Asp Asn Leu Asn Pro Asp Val Arg Leu Ile Leu Glu Glu 
            820                 825                 830         


Ile Thr Arg Phe Leu Asn Met Glu Lys Leu Leu Pro Ser Tyr Arg His 
        835                 840                 845             


Thr Ile Thr Val Ser Cys Leu Arg Ala Ile Arg Val Leu Gln Lys Asn 
    850                 855                 860                 


Gly His Val Pro Ser Asp Pro Ala Leu Phe Lys Ser Tyr Ala Glu Tyr 
865                 870                 875                 880 


Gly His Phe Val Asp Ile Arg Ile Ala Ala Leu Glu Ala Val Val Asp 
                885                 890                 895     


Tyr Thr Lys Val Asp Arg Ser Tyr Glu Glu Leu Gln Trp Leu Leu Asn 
            900                 905                 910         


Met Ile Gln Asn Asp Pro Val Pro Tyr Val Arg His Lys Ile Leu Asn 
        915                 920                 925             


Met Leu Thr Lys Asn Pro Pro Phe Thr Lys Asn Met Glu Ser Pro Leu 
    930                 935                 940                 


Cys Asn Glu Ala Leu Val Asp Gln Leu Trp Lys Leu Met Asn Ser Gly 
945                 950                 955                 960 


Thr Ser His Asp Trp Arg Leu Arg Cys Gly Ala Val Asp Leu Tyr Phe 
                965                 970                 975     


Thr Leu Phe Gly Leu Ser Arg Pro Ser Cys Leu Pro Leu Pro Glu Leu 
            980                 985                 990         


Gly Leu Val Leu Asn Leu Lys Glu  Lys Lys Ala Val Leu  Asn Pro Thr 
        995                 1000                 1005             


Ile Ile  Pro Glu Ser Val Ala  Gly Asn Gln Glu Ala  Ala Asn Asn 
    1010                 1015                 1020             


Pro Ser  Ser His Pro Gln Leu  Val Gly Phe Gln Asn  Pro Phe Ser 
    1025                 1030                 1035             


Ser Ser  Gln Asp Glu Glu Glu  Ile Asp Met Asp Thr  Val His Asp 
    1040                 1045                 1050             


Ser Gln  Ala Phe Ile Ser His  His Leu Asn Met Leu  Glu Arg Pro 
    1055                 1060                 1065             


Ser Thr  Pro Gly Leu Ser Lys  Tyr Arg Pro Ala Ser  Ser Arg Ser 
    1070                 1075                 1080             


Ala Leu  Ile Pro Gln His Ser  Ala Gly Cys Asp Ser  Thr Pro Thr 
    1085                 1090                 1095             


Thr Lys  Pro Gln Trp Ser Leu  Glu Leu Ala Arg Lys  Gly Thr Gly 
    1100                 1105                 1110             


Lys Glu  Gln Ala Pro Leu Glu  Met Ser Met His Pro  Ala Ala Ser 
    1115                 1120                 1125             


Ala Pro  Leu Ser Val Phe Thr  Lys Glu Ser Thr Ala  Ser Lys His 
    1130                 1135                 1140             


Ser Asp  His His His His His  His His Glu His Lys  Lys Lys Lys 
    1145                 1150                 1155             


Lys Lys  His Lys His Lys His  Lys His Lys His Lys  His Asp Ser 
    1160                 1165                 1170             


Lys Glu  Lys Asp Lys Glu Pro  Phe Thr Phe Ser Ser  Pro Ala Ser 
    1175                 1180                 1185             


Gly Arg  Ser Ile Arg Ser Pro  Ser Leu Ser Asp 
    1190                 1195                 


<210>  3311
<211>  199
<212>  PRT
<213>  homo sapiens

<400>  3311

Met Ala Asn Arg Gly Pro Ser Tyr Gly Leu Ser Arg Glu Val Gln Glu 
1               5                   10                  15      


Lys Ile Glu Gln Lys Tyr Asp Ala Asp Leu Glu Asn Lys Leu Val Asp 
            20                  25                  30          


Trp Ile Ile Leu Gln Cys Ala Glu Asp Ile Glu His Pro Pro Pro Gly 
        35                  40                  45              


Arg Ala His Phe Gln Lys Trp Leu Met Asp Gly Thr Val Leu Cys Lys 
    50                  55                  60                  


Leu Ile Asn Ser Leu Tyr Pro Pro Gly Gln Glu Pro Ile Pro Lys Ile 
65                  70                  75                  80  


Ser Glu Ser Lys Met Ala Phe Lys Gln Met Glu Gln Ile Ser Gln Phe 
                85                  90                  95      


Leu Lys Ala Ala Glu Thr Tyr Gly Val Arg Thr Thr Asp Ile Phe Gln 
            100                 105                 110         


Thr Val Asp Leu Trp Glu Gly Lys Asp Met Ala Ala Val Gln Arg Thr 
        115                 120                 125             


Leu Met Ala Leu Gly Ser Val Ala Val Thr Lys Asp Asp Gly Cys Tyr 
    130                 135                 140                 


Arg Gly Glu Pro Ser Trp Phe His Arg Lys Ala Gln Gln Asn Arg Arg 
145                 150                 155                 160 


Gly Phe Ser Glu Glu Gln Leu Arg Gln Gly Gln Asn Val Ile Gly Leu 
                165                 170                 175     


Gln Met Gly Ser Asn Lys Gly Ala Ser Gln Ala Gly Met Thr Gly Tyr 
            180                 185                 190         


Gly Met Pro Arg Gln Ile Met 
        195                 


<210>  3312
<211>  455
<212>  PRT
<213>  homo sapiens

<400>  3312

Met Glu Asn Lys Lys Lys Asp Lys Asp Lys Ser Asp Asp Arg Met Ala 
1               5                   10                  15      


Arg Pro Ser Gly Arg Ser Gly His Asn Thr Arg Gly Thr Gly Ser Ser 
            20                  25                  30          


Ser Ser Gly Val Leu Met Val Gly Pro Asn Phe Arg Val Gly Lys Lys 
        35                  40                  45              


Ile Gly Cys Gly Asn Phe Gly Glu Leu Arg Leu Gly Lys Asn Leu Tyr 
    50                  55                  60                  


Thr Asn Glu Tyr Val Ala Ile Lys Leu Glu Pro Met Lys Ser Arg Ala 
65                  70                  75                  80  


Pro Gln Leu His Leu Glu Tyr Arg Phe Tyr Lys Gln Leu Gly Ser Gly 
                85                  90                  95      


Asp Gly Ile Pro Gln Val Tyr Tyr Phe Gly Pro Cys Gly Lys Tyr Asn 
            100                 105                 110         


Ala Met Val Leu Glu Leu Leu Gly Pro Ser Leu Glu Asp Leu Phe Asp 
        115                 120                 125             


Leu Cys Asp Arg Thr Phe Ser Leu Lys Thr Val Leu Met Ile Ala Ile 
    130                 135                 140                 


Gln Leu Ile Ser Arg Met Glu Tyr Val His Ser Lys Asn Leu Ile Tyr 
145                 150                 155                 160 


Arg Asp Val Lys Pro Glu Asn Phe Leu Ile Gly Arg Pro Gly Asn Lys 
                165                 170                 175     


Thr Gln Gln Val Ile His Ile Ile Asp Phe Gly Leu Ala Lys Glu Tyr 
            180                 185                 190         


Ile Asp Pro Glu Thr Lys Lys His Ile Pro Tyr Arg Glu His Lys Ser 
        195                 200                 205             


Leu Thr Gly Thr Ala Arg Tyr Met Ser Ile Asn Thr His Leu Gly Lys 
    210                 215                 220                 


Glu Gln Ser Arg Arg Asp Asp Leu Glu Ala Leu Gly His Met Phe Met 
225                 230                 235                 240 


Tyr Phe Leu Arg Gly Ser Leu Pro Trp Gln Gly Leu Lys Ala Asp Thr 
                245                 250                 255     


Leu Lys Glu Arg Tyr Gln Lys Ile Gly Asp Thr Lys Arg Ala Thr Pro 
            260                 265                 270         


Ile Glu Val Leu Cys Glu Asn Phe Pro Glu Met Ala Thr Tyr Leu Arg 
        275                 280                 285             


Tyr Val Arg Arg Leu Asp Phe Phe Glu Lys Pro Asp Tyr Asp Tyr Leu 
    290                 295                 300                 


Arg Lys Leu Phe Thr Asp Leu Phe Asp Arg Lys Gly Tyr Met Phe Asp 
305                 310                 315                 320 


Tyr Glu Tyr Asp Trp Ile Gly Lys Gln Leu Pro Thr Pro Val Gly Ala 
                325                 330                 335     


Val Gln Gln Asp Pro Ala Leu Ser Ser Asn Arg Glu Ala His Gln His 
            340                 345                 350         


Arg Asp Lys Met Gln Gln Ser Lys Asn Gln Ser Ala Asp His Arg Ala 
        355                 360                 365             


Ala Trp Asp Ser Gln Gln Ala Asn Pro His His Leu Arg Ala His Leu 
    370                 375                 380                 


Ala Ala Asp Arg His Gly Gly Ser Val Gln Val Val Ser Ser Thr Asn 
385                 390                 395                 400 


Gly Glu Leu Asn Thr Asp Asp Pro Thr Ala Gly Arg Ser Asn Ala Pro 
                405                 410                 415     


Ile Thr Ala Pro Thr Glu Val Glu Val Met Asp Glu Thr Asn Cys Gln 
            420                 425                 430         


Lys Val Leu Asn Met Trp Cys Cys Cys Phe Phe Lys Arg Arg Lys Arg 
        435                 440                 445             


Lys Thr Ile Gln Arg His Lys 
    450                 455 


<210>  3313
<211>  2843
<212>  PRT
<213>  homo sapiens

<400>  3313

Met Ala Ala Ala Ser Tyr Asp Gln Leu Leu Lys Gln Val Glu Ala Leu 
1               5                   10                  15      


Lys Met Glu Asn Ser Asn Leu Arg Gln Glu Leu Glu Asp Asn Ser Asn 
            20                  25                  30          


His Leu Thr Lys Leu Glu Thr Glu Ala Ser Asn Met Lys Glu Val Leu 
        35                  40                  45              


Lys Gln Leu Gln Gly Ser Ile Glu Asp Glu Ala Met Ala Ser Ser Gly 
    50                  55                  60                  


Gln Ile Asp Leu Leu Glu Arg Leu Lys Glu Leu Asn Leu Asp Ser Ser 
65                  70                  75                  80  


Asn Phe Pro Gly Val Lys Leu Arg Ser Lys Met Ser Leu Arg Ser Tyr 
                85                  90                  95      


Gly Ser Arg Glu Gly Ser Val Ser Ser Arg Ser Gly Glu Cys Ser Pro 
            100                 105                 110         


Val Pro Met Gly Ser Phe Pro Arg Arg Gly Phe Val Asn Gly Ser Arg 
        115                 120                 125             


Glu Ser Thr Gly Tyr Leu Glu Glu Leu Glu Lys Glu Arg Ser Leu Leu 
    130                 135                 140                 


Leu Ala Asp Leu Asp Lys Glu Glu Lys Glu Lys Asp Trp Tyr Tyr Ala 
145                 150                 155                 160 


Gln Leu Gln Asn Leu Thr Lys Arg Ile Asp Ser Leu Pro Leu Thr Glu 
                165                 170                 175     


Asn Phe Ser Leu Gln Thr Asp Met Thr Arg Arg Gln Leu Glu Tyr Glu 
            180                 185                 190         


Ala Arg Gln Ile Arg Val Ala Met Glu Glu Gln Leu Gly Thr Cys Gln 
        195                 200                 205             


Asp Met Glu Lys Arg Ala Gln Arg Arg Ile Ala Arg Ile Gln Gln Ile 
    210                 215                 220                 


Glu Lys Asp Ile Leu Arg Ile Arg Gln Leu Leu Gln Ser Gln Ala Thr 
225                 230                 235                 240 


Glu Ala Glu Arg Ser Ser Gln Asn Lys His Glu Thr Gly Ser His Asp 
                245                 250                 255     


Ala Glu Arg Gln Asn Glu Gly Gln Gly Val Gly Glu Ile Asn Met Ala 
            260                 265                 270         


Thr Ser Gly Asn Gly Gln Gly Ser Thr Thr Arg Met Asp His Glu Thr 
        275                 280                 285             


Ala Ser Val Leu Ser Ser Ser Ser Thr His Ser Ala Pro Arg Arg Leu 
    290                 295                 300                 


Thr Ser His Leu Gly Thr Lys Val Glu Met Val Tyr Ser Leu Leu Ser 
305                 310                 315                 320 


Met Leu Gly Thr His Asp Lys Asp Asp Met Ser Arg Thr Leu Leu Ala 
                325                 330                 335     


Met Ser Ser Ser Gln Asp Ser Cys Ile Ser Met Arg Gln Ser Gly Cys 
            340                 345                 350         


Leu Pro Leu Leu Ile Gln Leu Leu His Gly Asn Asp Lys Asp Ser Val 
        355                 360                 365             


Leu Leu Gly Asn Ser Arg Gly Ser Lys Glu Ala Arg Ala Arg Ala Ser 
    370                 375                 380                 


Ala Ala Leu His Asn Ile Ile His Ser Gln Pro Asp Asp Lys Arg Gly 
385                 390                 395                 400 


Arg Arg Glu Ile Arg Val Leu His Leu Leu Glu Gln Ile Arg Ala Tyr 
                405                 410                 415     


Cys Glu Thr Cys Trp Glu Trp Gln Glu Ala His Glu Pro Gly Met Asp 
            420                 425                 430         


Gln Asp Lys Asn Pro Met Pro Ala Pro Val Glu His Gln Ile Cys Pro 
        435                 440                 445             


Ala Val Cys Val Leu Met Lys Leu Ser Phe Asp Glu Glu His Arg His 
    450                 455                 460                 


Ala Met Asn Glu Leu Gly Gly Leu Gln Ala Ile Ala Glu Leu Leu Gln 
465                 470                 475                 480 


Val Asp Cys Glu Met Tyr Gly Leu Thr Asn Asp His Tyr Ser Ile Thr 
                485                 490                 495     


Leu Arg Arg Tyr Ala Gly Met Ala Leu Thr Asn Leu Thr Phe Gly Asp 
            500                 505                 510         


Val Ala Asn Lys Ala Thr Leu Cys Ser Met Lys Gly Cys Met Arg Ala 
        515                 520                 525             


Leu Val Ala Gln Leu Lys Ser Glu Ser Glu Asp Leu Gln Gln Val Ile 
    530                 535                 540                 


Ala Ser Val Leu Arg Asn Leu Ser Trp Arg Ala Asp Val Asn Ser Lys 
545                 550                 555                 560 


Lys Thr Leu Arg Glu Val Gly Ser Val Lys Ala Leu Met Glu Cys Ala 
                565                 570                 575     


Leu Glu Val Lys Lys Glu Ser Thr Leu Lys Ser Val Leu Ser Ala Leu 
            580                 585                 590         


Trp Asn Leu Ser Ala His Cys Thr Glu Asn Lys Ala Asp Ile Cys Ala 
        595                 600                 605             


Val Asp Gly Ala Leu Ala Phe Leu Val Gly Thr Leu Thr Tyr Arg Ser 
    610                 615                 620                 


Gln Thr Asn Thr Leu Ala Ile Ile Glu Ser Gly Gly Gly Ile Leu Arg 
625                 630                 635                 640 


Asn Val Ser Ser Leu Ile Ala Thr Asn Glu Asp His Arg Gln Ile Leu 
                645                 650                 655     


Arg Glu Asn Asn Cys Leu Gln Thr Leu Leu Gln His Leu Lys Ser His 
            660                 665                 670         


Ser Leu Thr Ile Val Ser Asn Ala Cys Gly Thr Leu Trp Asn Leu Ser 
        675                 680                 685             


Ala Arg Asn Pro Lys Asp Gln Glu Ala Leu Trp Asp Met Gly Ala Val 
    690                 695                 700                 


Ser Met Leu Lys Asn Leu Ile His Ser Lys His Lys Met Ile Ala Met 
705                 710                 715                 720 


Gly Ser Ala Ala Ala Leu Arg Asn Leu Met Ala Asn Arg Pro Ala Lys 
                725                 730                 735     


Tyr Lys Asp Ala Asn Ile Met Ser Pro Gly Ser Ser Leu Pro Ser Leu 
            740                 745                 750         


His Val Arg Lys Gln Lys Ala Leu Glu Ala Glu Leu Asp Ala Gln His 
        755                 760                 765             


Leu Ser Glu Thr Phe Asp Asn Ile Asp Asn Leu Ser Pro Lys Ala Ser 
    770                 775                 780                 


His Arg Ser Lys Gln Arg His Lys Gln Ser Leu Tyr Gly Asp Tyr Val 
785                 790                 795                 800 


Phe Asp Thr Asn Arg His Asp Asp Asn Arg Ser Asp Asn Phe Asn Thr 
                805                 810                 815     


Gly Asn Met Thr Val Leu Ser Pro Tyr Leu Asn Thr Thr Val Leu Pro 
            820                 825                 830         


Ser Ser Ser Ser Ser Arg Gly Ser Leu Asp Ser Ser Arg Ser Glu Lys 
        835                 840                 845             


Asp Arg Ser Leu Glu Arg Glu Arg Gly Ile Gly Leu Gly Asn Tyr His 
    850                 855                 860                 


Pro Ala Thr Glu Asn Pro Gly Thr Ser Ser Lys Arg Gly Leu Gln Ile 
865                 870                 875                 880 


Ser Thr Thr Ala Ala Gln Ile Ala Lys Val Met Glu Glu Val Ser Ala 
                885                 890                 895     


Ile His Thr Ser Gln Glu Asp Arg Ser Ser Gly Ser Thr Thr Glu Leu 
            900                 905                 910         


His Cys Val Thr Asp Glu Arg Asn Ala Leu Arg Arg Ser Ser Ala Ala 
        915                 920                 925             


His Thr His Ser Asn Thr Tyr Asn Phe Thr Lys Ser Glu Asn Ser Asn 
    930                 935                 940                 


Arg Thr Cys Ser Met Pro Tyr Ala Lys Leu Glu Tyr Lys Arg Ser Ser 
945                 950                 955                 960 


Asn Asp Ser Leu Asn Ser Val Ser Ser Ser Asp Gly Tyr Gly Lys Arg 
                965                 970                 975     


Gly Gln Met Lys Pro Ser Ile Glu Ser Tyr Ser Glu Asp Asp Glu Ser 
            980                 985                 990         


Lys Phe Cys Ser Tyr Gly Gln Tyr  Pro Ala Asp Leu Ala  His Lys Ile 
        995                 1000                 1005             


His Ser  Ala Asn His Met Asp  Asp Asn Asp Gly Glu  Leu Asp Thr 
    1010                 1015                 1020             


Pro Ile  Asn Tyr Ser Leu Lys  Tyr Ser Asp Glu Gln  Leu Asn Ser 
    1025                 1030                 1035             


Gly Arg  Gln Ser Pro Ser Gln  Asn Glu Arg Trp Ala  Arg Pro Lys 
    1040                 1045                 1050             


His Ile  Ile Glu Asp Glu Ile  Lys Gln Ser Glu Gln  Arg Gln Ser 
    1055                 1060                 1065             


Arg Asn  Gln Ser Thr Thr Tyr  Pro Val Tyr Thr Glu  Ser Thr Asp 
    1070                 1075                 1080             


Asp Lys  His Leu Lys Phe Gln  Pro His Phe Gly Gln  Gln Glu Cys 
    1085                 1090                 1095             


Val Ser  Pro Tyr Arg Ser Arg  Gly Ala Asn Gly Ser  Glu Thr Asn 
    1100                 1105                 1110             


Arg Val  Gly Ser Asn His Gly  Ile Asn Gln Asn Val  Ser Gln Ser 
    1115                 1120                 1125             


Leu Cys  Gln Glu Asp Asp Tyr  Glu Asp Asp Lys Pro  Thr Asn Tyr 
    1130                 1135                 1140             


Ser Glu  Arg Tyr Ser Glu Glu  Glu Gln His Glu Glu  Glu Glu Arg 
    1145                 1150                 1155             


Pro Thr  Asn Tyr Ser Ile Lys  Tyr Asn Glu Glu Lys  Arg His Val 
    1160                 1165                 1170             


Asp Gln  Pro Ile Asp Tyr Ser  Leu Lys Tyr Ala Thr  Asp Ile Pro 
    1175                 1180                 1185             


Ser Ser  Gln Lys Gln Ser Phe  Ser Phe Ser Lys Ser  Ser Ser Gly 
    1190                 1195                 1200             


Gln Ser  Ser Lys Thr Glu His  Met Ser Ser Ser Ser  Glu Asn Thr 
    1205                 1210                 1215             


Ser Thr  Pro Ser Ser Asn Ala  Lys Arg Gln Asn Gln  Leu His Pro 
    1220                 1225                 1230             


Ser Ser  Ala Gln Ser Arg Ser  Gly Gln Pro Gln Lys  Ala Ala Thr 
    1235                 1240                 1245             


Cys Lys  Val Ser Ser Ile Asn  Gln Glu Thr Ile Gln  Thr Tyr Cys 
    1250                 1255                 1260             


Val Glu  Asp Thr Pro Ile Cys  Phe Ser Arg Cys Ser  Ser Leu Ser 
    1265                 1270                 1275             


Ser Leu  Ser Ser Ala Glu Asp  Glu Ile Gly Cys Asn  Gln Thr Thr 
    1280                 1285                 1290             


Gln Glu  Ala Asp Ser Ala Asn  Thr Leu Gln Ile Ala  Glu Ile Lys 
    1295                 1300                 1305             


Glu Lys  Ile Gly Thr Arg Ser  Ala Glu Asp Pro Val  Ser Glu Val 
    1310                 1315                 1320             


Pro Ala  Val Ser Gln His Pro  Arg Thr Lys Ser Ser  Arg Leu Gln 
    1325                 1330                 1335             


Gly Ser  Ser Leu Ser Ser Glu  Ser Ala Arg His Lys  Ala Val Glu 
    1340                 1345                 1350             


Phe Ser  Ser Gly Ala Lys Ser  Pro Ser Lys Ser Gly  Ala Gln Thr 
    1355                 1360                 1365             


Pro Lys  Ser Pro Pro Glu His  Tyr Val Gln Glu Thr  Pro Leu Met 
    1370                 1375                 1380             


Phe Ser  Arg Cys Thr Ser Val  Ser Ser Leu Asp Ser  Phe Glu Ser 
    1385                 1390                 1395             


Arg Ser  Ile Ala Ser Ser Val  Gln Ser Glu Pro Cys  Ser Gly Met 
    1400                 1405                 1410             


Val Ser  Gly Ile Ile Ser Pro  Ser Asp Leu Pro Asp  Ser Pro Gly 
    1415                 1420                 1425             


Gln Thr  Met Pro Pro Ser Arg  Ser Lys Thr Pro Pro  Pro Pro Pro 
    1430                 1435                 1440             


Gln Thr  Ala Gln Thr Lys Arg  Glu Val Pro Lys Asn  Lys Ala Pro 
    1445                 1450                 1455             


Thr Ala  Glu Lys Arg Glu Ser  Gly Pro Lys Gln Ala  Ala Val Asn 
    1460                 1465                 1470             


Ala Ala  Val Gln Arg Val Gln  Val Leu Pro Asp Ala  Asp Thr Leu 
    1475                 1480                 1485             


Leu His  Phe Ala Thr Glu Ser  Thr Pro Asp Gly Phe  Ser Cys Ser 
    1490                 1495                 1500             


Ser Ser  Leu Ser Ala Leu Ser  Leu Asp Glu Pro Phe  Ile Gln Lys 
    1505                 1510                 1515             


Asp Val  Glu Leu Arg Ile Met  Pro Pro Val Gln Glu  Asn Asp Asn 
    1520                 1525                 1530             


Gly Asn  Glu Thr Glu Ser Glu  Gln Pro Lys Glu Ser  Asn Glu Asn 
    1535                 1540                 1545             


Gln Glu  Lys Glu Ala Glu Lys  Thr Ile Asp Ser Glu  Lys Asp Leu 
    1550                 1555                 1560             


Leu Asp  Asp Ser Asp Asp Asp  Asp Ile Glu Ile Leu  Glu Glu Cys 
    1565                 1570                 1575             


Ile Ile  Ser Ala Met Pro Thr  Lys Ser Ser Arg Lys  Ala Lys Lys 
    1580                 1585                 1590             


Pro Ala  Gln Thr Ala Ser Lys  Leu Pro Pro Pro Val  Ala Arg Lys 
    1595                 1600                 1605             


Pro Ser  Gln Leu Pro Val Tyr  Lys Leu Leu Pro Ser  Gln Asn Arg 
    1610                 1615                 1620             


Leu Gln  Pro Gln Lys His Val  Ser Phe Thr Pro Gly  Asp Asp Met 
    1625                 1630                 1635             


Pro Arg  Val Tyr Cys Val Glu  Gly Thr Pro Ile Asn  Phe Ser Thr 
    1640                 1645                 1650             


Ala Thr  Ser Leu Ser Asp Leu  Thr Ile Glu Ser Pro  Pro Asn Glu 
    1655                 1660                 1665             


Leu Ala  Ala Gly Glu Gly Val  Arg Gly Gly Ala Gln  Ser Gly Glu 
    1670                 1675                 1680             


Phe Glu  Lys Arg Asp Thr Ile  Pro Thr Glu Gly Arg  Ser Thr Asp 
    1685                 1690                 1695             


Glu Ala  Gln Gly Gly Lys Thr  Ser Ser Val Thr Ile  Pro Glu Leu 
    1700                 1705                 1710             


Asp Asp  Asn Lys Ala Glu Glu  Gly Asp Ile Leu Ala  Glu Cys Ile 
    1715                 1720                 1725             


Asn Ser  Ala Met Pro Lys Gly  Lys Ser His Lys Pro  Phe Arg Val 
    1730                 1735                 1740             


Lys Lys  Ile Met Asp Gln Val  Gln Gln Ala Ser Ala  Ser Ser Ser 
    1745                 1750                 1755             


Ala Pro  Asn Lys Asn Gln Leu  Asp Gly Lys Lys Lys  Lys Pro Thr 
    1760                 1765                 1770             


Ser Pro  Val Lys Pro Ile Pro  Gln Asn Thr Glu Tyr  Arg Thr Arg 
    1775                 1780                 1785             


Val Arg  Lys Asn Ala Asp Ser  Lys Asn Asn Leu Asn  Ala Glu Arg 
    1790                 1795                 1800             


Val Phe  Ser Asp Asn Lys Asp  Ser Lys Lys Gln Asn  Leu Lys Asn 
    1805                 1810                 1815             


Asn Ser  Lys Val Phe Asn Asp  Lys Leu Pro Asn Asn  Glu Asp Arg 
    1820                 1825                 1830             


Val Arg  Gly Ser Phe Ala Phe  Asp Ser Pro His His  Tyr Thr Pro 
    1835                 1840                 1845             


Ile Glu  Gly Thr Pro Tyr Cys  Phe Ser Arg Asn Asp  Ser Leu Ser 
    1850                 1855                 1860             


Ser Leu  Asp Phe Asp Asp Asp  Asp Val Asp Leu Ser  Arg Glu Lys 
    1865                 1870                 1875             


Ala Glu  Leu Arg Lys Ala Lys  Glu Asn Lys Glu Ser  Glu Ala Lys 
    1880                 1885                 1890             


Val Thr  Ser His Thr Glu Leu  Thr Ser Asn Gln Gln  Ser Ala Asn 
    1895                 1900                 1905             


Lys Thr  Gln Ala Ile Ala Lys  Gln Pro Ile Asn Arg  Gly Gln Pro 
    1910                 1915                 1920             


Lys Pro  Ile Leu Gln Lys Gln  Ser Thr Phe Pro Gln  Ser Ser Lys 
    1925                 1930                 1935             


Asp Ile  Pro Asp Arg Gly Ala  Ala Thr Asp Glu Lys  Leu Gln Asn 
    1940                 1945                 1950             


Phe Ala  Ile Glu Asn Thr Pro  Val Cys Phe Ser His  Asn Ser Ser 
    1955                 1960                 1965             


Leu Ser  Ser Leu Ser Asp Ile  Asp Gln Glu Asn Asn  Asn Lys Glu 
    1970                 1975                 1980             


Asn Glu  Pro Ile Lys Glu Thr  Glu Pro Pro Asp Ser  Gln Gly Glu 
    1985                 1990                 1995             


Pro Ser  Lys Pro Gln Ala Ser  Gly Tyr Ala Pro Lys  Ser Phe His 
    2000                 2005                 2010             


Val Glu  Asp Thr Pro Val Cys  Phe Ser Arg Asn Ser  Ser Leu Ser 
    2015                 2020                 2025             


Ser Leu  Ser Ile Asp Ser Glu  Asp Asp Leu Leu Gln  Glu Cys Ile 
    2030                 2035                 2040             


Ser Ser  Ala Met Pro Lys Lys  Lys Lys Pro Ser Arg  Leu Lys Gly 
    2045                 2050                 2055             


Asp Asn  Glu Lys His Ser Pro  Arg Asn Met Gly Gly  Ile Leu Gly 
    2060                 2065                 2070             


Glu Asp  Leu Thr Leu Asp Leu  Lys Asp Ile Gln Arg  Pro Asp Ser 
    2075                 2080                 2085             


Glu His  Gly Leu Ser Pro Asp  Ser Glu Asn Phe Asp  Trp Lys Ala 
    2090                 2095                 2100             


Ile Gln  Glu Gly Ala Asn Ser  Ile Val Ser Ser Leu  His Gln Ala 
    2105                 2110                 2115             


Ala Ala  Ala Ala Cys Leu Ser  Arg Gln Ala Ser Ser  Asp Ser Asp 
    2120                 2125                 2130             


Ser Ile  Leu Ser Leu Lys Ser  Gly Ile Ser Leu Gly  Ser Pro Phe 
    2135                 2140                 2145             


His Leu  Thr Pro Asp Gln Glu  Glu Lys Pro Phe Thr  Ser Asn Lys 
    2150                 2155                 2160             


Gly Pro  Arg Ile Leu Lys Pro  Gly Glu Lys Ser Thr  Leu Glu Thr 
    2165                 2170                 2175             


Lys Lys  Ile Glu Ser Glu Ser  Lys Gly Ile Lys Gly  Gly Lys Lys 
    2180                 2185                 2190             


Val Tyr  Lys Ser Leu Ile Thr  Gly Lys Val Arg Ser  Asn Ser Glu 
    2195                 2200                 2205             


Ile Ser  Gly Gln Met Lys Gln  Pro Leu Gln Ala Asn  Met Pro Ser 
    2210                 2215                 2220             


Ile Ser  Arg Gly Arg Thr Met  Ile His Ile Pro Gly  Val Arg Asn 
    2225                 2230                 2235             


Ser Ser  Ser Ser Thr Ser Pro  Val Ser Lys Lys Gly  Pro Pro Leu 
    2240                 2245                 2250             


Lys Thr  Pro Ala Ser Lys Ser  Pro Ser Glu Gly Gln  Thr Ala Thr 
    2255                 2260                 2265             


Thr Ser  Pro Arg Gly Ala Lys  Pro Ser Val Lys Ser  Glu Leu Ser 
    2270                 2275                 2280             


Pro Val  Ala Arg Gln Thr Ser  Gln Ile Gly Gly Ser  Ser Lys Ala 
    2285                 2290                 2295             


Pro Ser  Arg Ser Gly Ser Arg  Asp Ser Thr Pro Ser  Arg Pro Ala 
    2300                 2305                 2310             


Gln Gln  Pro Leu Ser Arg Pro  Ile Gln Ser Pro Gly  Arg Asn Ser 
    2315                 2320                 2325             


Ile Ser  Pro Gly Arg Asn Gly  Ile Ser Pro Pro Asn  Lys Leu Ser 
    2330                 2335                 2340             


Gln Leu  Pro Arg Thr Ser Ser  Pro Ser Thr Ala Ser  Thr Lys Ser 
    2345                 2350                 2355             


Ser Gly  Ser Gly Lys Met Ser  Tyr Thr Ser Pro Gly  Arg Gln Met 
    2360                 2365                 2370             


Ser Gln  Gln Asn Leu Thr Lys  Gln Thr Gly Leu Ser  Lys Asn Ala 
    2375                 2380                 2385             


Ser Ser  Ile Pro Arg Ser Glu  Ser Ala Ser Lys Gly  Leu Asn Gln 
    2390                 2395                 2400             


Met Asn  Asn Gly Asn Gly Ala  Asn Lys Lys Val Glu  Leu Ser Arg 
    2405                 2410                 2415             


Met Ser  Ser Thr Lys Ser Ser  Gly Ser Glu Ser Asp  Arg Ser Glu 
    2420                 2425                 2430             


Arg Pro  Val Leu Val Arg Gln  Ser Thr Phe Ile Lys  Glu Ala Pro 
    2435                 2440                 2445             


Ser Pro  Thr Leu Arg Arg Lys  Leu Glu Glu Ser Ala  Ser Phe Glu 
    2450                 2455                 2460             


Ser Leu  Ser Pro Ser Ser Arg  Pro Ala Ser Pro Thr  Arg Ser Gln 
    2465                 2470                 2475             


Ala Gln  Thr Pro Val Leu Ser  Pro Ser Leu Pro Asp  Met Ser Leu 
    2480                 2485                 2490             


Ser Thr  His Ser Ser Val Gln  Ala Gly Gly Trp Arg  Lys Leu Pro 
    2495                 2500                 2505             


Pro Asn  Leu Ser Pro Thr Ile  Glu Tyr Asn Asp Gly  Arg Pro Ala 
    2510                 2515                 2520             


Lys Arg  His Asp Ile Ala Arg  Ser His Ser Glu Ser  Pro Ser Arg 
    2525                 2530                 2535             


Leu Pro  Ile Asn Arg Ser Gly  Thr Trp Lys Arg Glu  His Ser Lys 
    2540                 2545                 2550             


His Ser  Ser Ser Leu Pro Arg  Val Ser Thr Trp Arg  Arg Thr Gly 
    2555                 2560                 2565             


Ser Ser  Ser Ser Ile Leu Ser  Ala Ser Ser Glu Ser  Ser Glu Lys 
    2570                 2575                 2580             


Ala Lys  Ser Glu Asp Glu Lys  His Val Asn Ser Ile  Ser Gly Thr 
    2585                 2590                 2595             


Lys Gln  Ser Lys Glu Asn Gln  Val Ser Ala Lys Gly  Thr Trp Arg 
    2600                 2605                 2610             


Lys Ile  Lys Glu Asn Glu Phe  Ser Pro Thr Asn Ser  Thr Ser Gln 
    2615                 2620                 2625             


Thr Val  Ser Ser Gly Ala Thr  Asn Gly Ala Glu Ser  Lys Thr Leu 
    2630                 2635                 2640             


Ile Tyr  Gln Met Ala Pro Ala  Val Ser Lys Thr Glu  Asp Val Trp 
    2645                 2650                 2655             


Val Arg  Ile Glu Asp Cys Pro  Ile Asn Asn Pro Arg  Ser Gly Arg 
    2660                 2665                 2670             


Ser Pro  Thr Gly Asn Thr Pro  Pro Val Ile Asp Ser  Val Ser Glu 
    2675                 2680                 2685             


Lys Ala  Asn Pro Asn Ile Lys  Asp Ser Lys Asp Asn  Gln Ala Lys 
    2690                 2695                 2700             


Gln Asn  Val Gly Asn Gly Ser  Val Pro Met Arg Thr  Val Gly Leu 
    2705                 2710                 2715             


Glu Asn  Arg Leu Asn Ser Phe  Ile Gln Val Asp Ala  Pro Asp Gln 
    2720                 2725                 2730             


Lys Gly  Thr Glu Ile Lys Pro  Gly Gln Asn Asn Pro  Val Pro Val 
    2735                 2740                 2745             


Ser Glu  Thr Asn Glu Ser Ser  Ile Val Glu Arg Thr  Pro Phe Ser 
    2750                 2755                 2760             


Ser Ser  Ser Ser Ser Lys His  Ser Ser Pro Ser Gly  Thr Val Ala 
    2765                 2770                 2775             


Ala Arg  Val Thr Pro Phe Asn  Tyr Asn Pro Ser Pro  Arg Lys Ser 
    2780                 2785                 2790             


Ser Ala  Asp Ser Thr Ser Ala  Arg Pro Ser Gln Ile  Pro Thr Pro 
    2795                 2800                 2805             


Val Asn  Asn Asn Thr Lys Lys  Arg Asp Ser Lys Thr  Asp Ser Thr 
    2810                 2815                 2820             


Glu Ser  Ser Gly Thr Gln Ser  Pro Lys Arg His Ser  Gly Ser Tyr 
    2825                 2830                 2835             


Leu Val  Thr Ser Val 
    2840             


<210>  3314
<211>  543
<212>  PRT
<213>  homo sapiens

<400>  3314

Met Ala Ala Ala Lys Ala Glu Met Gln Leu Met Ser Pro Leu Gln Ile 
1               5                   10                  15      


Ser Asp Pro Phe Gly Ser Phe Pro His Ser Pro Thr Met Asp Asn Tyr 
            20                  25                  30          


Pro Lys Leu Glu Glu Met Met Leu Leu Ser Asn Gly Ala Pro Gln Phe 
        35                  40                  45              


Leu Gly Ala Ala Gly Ala Pro Glu Gly Ser Gly Ser Asn Ser Ser Ser 
    50                  55                  60                  


Ser Ser Ser Gly Gly Gly Gly Gly Gly Gly Gly Gly Ser Asn Ser Ser 
65                  70                  75                  80  


Ser Ser Ser Ser Thr Phe Asn Pro Gln Ala Asp Thr Gly Glu Gln Pro 
                85                  90                  95      


Tyr Glu His Leu Thr Ala Glu Ser Phe Pro Asp Ile Ser Leu Asn Asn 
            100                 105                 110         


Glu Lys Val Leu Val Glu Thr Ser Tyr Pro Ser Gln Thr Thr Arg Leu 
        115                 120                 125             


Pro Pro Ile Thr Tyr Thr Gly Arg Phe Ser Leu Glu Pro Ala Pro Asn 
    130                 135                 140                 


Ser Gly Asn Thr Leu Trp Pro Glu Pro Leu Phe Ser Leu Val Ser Gly 
145                 150                 155                 160 


Leu Val Ser Met Thr Asn Pro Pro Ala Ser Ser Ser Ser Ala Pro Ser 
                165                 170                 175     


Pro Ala Ala Ser Ser Ala Ser Ala Ser Gln Ser Pro Pro Leu Ser Cys 
            180                 185                 190         


Ala Val Pro Ser Asn Asp Ser Ser Pro Ile Tyr Ser Ala Ala Pro Thr 
        195                 200                 205             


Phe Pro Thr Pro Asn Thr Asp Ile Phe Pro Glu Pro Gln Ser Gln Ala 
    210                 215                 220                 


Phe Pro Gly Ser Ala Gly Thr Ala Leu Gln Tyr Pro Pro Pro Ala Tyr 
225                 230                 235                 240 


Pro Ala Ala Lys Gly Gly Phe Gln Val Pro Met Ile Pro Asp Tyr Leu 
                245                 250                 255     


Phe Pro Gln Gln Gln Gly Asp Leu Gly Leu Gly Thr Pro Asp Gln Lys 
            260                 265                 270         


Pro Phe Gln Gly Leu Glu Ser Arg Thr Gln Gln Pro Ser Leu Thr Pro 
        275                 280                 285             


Leu Ser Thr Ile Lys Ala Phe Ala Thr Gln Ser Gly Ser Gln Asp Leu 
    290                 295                 300                 


Lys Ala Leu Asn Thr Ser Tyr Gln Ser Gln Leu Ile Lys Pro Ser Arg 
305                 310                 315                 320 


Met Arg Lys Tyr Pro Asn Arg Pro Ser Lys Thr Pro Pro His Glu Arg 
                325                 330                 335     


Pro Tyr Ala Cys Pro Val Glu Ser Cys Asp Arg Arg Phe Ser Arg Ser 
            340                 345                 350         


Asp Glu Leu Thr Arg His Ile Arg Ile His Thr Gly Gln Lys Pro Phe 
        355                 360                 365             


Gln Cys Arg Ile Cys Met Arg Asn Phe Ser Arg Ser Asp His Leu Thr 
    370                 375                 380                 


Thr His Ile Arg Thr His Thr Gly Glu Lys Pro Phe Ala Cys Asp Ile 
385                 390                 395                 400 


Cys Gly Arg Lys Phe Ala Arg Ser Asp Glu Arg Lys Arg His Thr Lys 
                405                 410                 415     


Ile His Leu Arg Gln Lys Asp Lys Lys Ala Asp Lys Ser Val Val Ala 
            420                 425                 430         


Ser Ser Ala Thr Ser Ser Leu Ser Ser Tyr Pro Ser Pro Val Ala Thr 
        435                 440                 445             


Ser Tyr Pro Ser Pro Val Thr Thr Ser Tyr Pro Ser Pro Ala Thr Thr 
    450                 455                 460                 


Ser Tyr Pro Ser Pro Val Pro Thr Ser Phe Ser Ser Pro Gly Ser Ser 
465                 470                 475                 480 


Thr Tyr Pro Ser Pro Val His Ser Gly Phe Pro Ser Pro Ser Val Ala 
                485                 490                 495     


Thr Thr Tyr Ser Ser Val Pro Pro Ala Phe Pro Ala Gln Val Ser Ser 
            500                 505                 510         


Phe Pro Ser Ser Ala Val Thr Asn Ser Phe Ser Ala Ser Thr Gly Leu 
        515                 520                 525             


Ser Asp Met Thr Ala Thr Phe Ser Pro Arg Thr Ile Glu Ile Cys 
    530                 535                 540             


<210>  3315
<211>  476
<212>  PRT
<213>  homo sapiens

<400>  3315

Met Met Thr Ala Lys Ala Val Asp Lys Ile Pro Val Thr Leu Ser Gly 
1               5                   10                  15      


Phe Val His Gln Leu Ser Asp Asn Ile Tyr Pro Val Glu Asp Leu Ala 
            20                  25                  30          


Ala Thr Ser Val Thr Ile Phe Pro Asn Ala Glu Leu Gly Gly Pro Phe 
        35                  40                  45              


Asp Gln Met Asn Gly Val Ala Gly Asp Gly Met Ile Asn Ile Asp Met 
    50                  55                  60                  


Thr Gly Glu Lys Arg Ser Leu Asp Leu Pro Tyr Pro Ser Ser Phe Ala 
65                  70                  75                  80  


Pro Val Ser Ala Pro Arg Asn Gln Thr Phe Thr Tyr Met Gly Lys Phe 
                85                  90                  95      


Ser Ile Asp Pro Gln Tyr Pro Gly Ala Ser Cys Tyr Pro Glu Gly Ile 
            100                 105                 110         


Ile Asn Ile Val Ser Ala Gly Ile Leu Gln Gly Val Thr Ser Pro Ala 
        115                 120                 125             


Ser Thr Thr Ala Ser Ser Ser Val Thr Ser Ala Ser Pro Asn Pro Leu 
    130                 135                 140                 


Ala Thr Gly Pro Leu Gly Val Cys Thr Met Ser Gln Thr Gln Pro Asp 
145                 150                 155                 160 


Leu Asp His Leu Tyr Ser Pro Pro Pro Pro Pro Pro Pro Tyr Ser Gly 
                165                 170                 175     


Cys Ala Gly Asp Leu Tyr Gln Asp Pro Ser Ala Phe Leu Ser Ala Ala 
            180                 185                 190         


Thr Thr Ser Thr Ser Ser Ser Leu Ala Tyr Pro Pro Pro Pro Ser Tyr 
        195                 200                 205             


Pro Ser Pro Lys Pro Ala Thr Asp Pro Gly Leu Phe Pro Met Ile Pro 
    210                 215                 220                 


Asp Tyr Pro Gly Phe Phe Pro Ser Gln Cys Gln Arg Asp Leu His Gly 
225                 230                 235                 240 


Thr Ala Gly Pro Asp Arg Lys Pro Phe Pro Cys Pro Leu Asp Thr Leu 
                245                 250                 255     


Arg Val Pro Pro Pro Leu Thr Pro Leu Ser Thr Ile Arg Asn Phe Thr 
            260                 265                 270         


Leu Gly Gly Pro Ser Ala Gly Val Thr Gly Pro Gly Ala Ser Gly Gly 
        275                 280                 285             


Ser Glu Gly Pro Arg Leu Pro Gly Ser Ser Ser Ala Ala Ala Ala Ala 
    290                 295                 300                 


Ala Ala Ala Ala Ala Tyr Asn Pro His His Leu Pro Leu Arg Pro Ile 
305                 310                 315                 320 


Leu Arg Pro Arg Lys Tyr Pro Asn Arg Pro Ser Lys Thr Pro Val His 
                325                 330                 335     


Glu Arg Pro Tyr Pro Cys Pro Ala Glu Gly Cys Asp Arg Arg Phe Ser 
            340                 345                 350         


Arg Ser Asp Glu Leu Thr Arg His Ile Arg Ile His Thr Gly His Lys 
        355                 360                 365             


Pro Phe Gln Cys Arg Ile Cys Met Arg Asn Phe Ser Arg Ser Asp His 
    370                 375                 380                 


Leu Thr Thr His Ile Arg Thr His Thr Gly Glu Lys Pro Phe Ala Cys 
385                 390                 395                 400 


Asp Tyr Cys Gly Arg Lys Phe Ala Arg Ser Asp Glu Arg Lys Arg His 
                405                 410                 415     


Thr Lys Ile His Leu Arg Gln Lys Glu Arg Lys Ser Ser Ala Pro Ser 
            420                 425                 430         


Ala Ser Val Pro Ala Pro Ser Thr Ala Ser Cys Ser Gly Gly Val Gln 
        435                 440                 445             


Pro Gly Gly Thr Leu Cys Ser Ser Asn Ser Ser Ser Leu Gly Gly Gly 
    450                 455                 460                 


Pro Leu Ala Pro Cys Ser Ser Arg Thr Arg Thr Pro 
465                 470                 475     


<210>  3316
<211>  476
<212>  PRT
<213>  homo sapiens

<400>  3316

Met Met Thr Ala Lys Ala Val Asp Lys Ile Pro Val Thr Leu Ser Gly 
1               5                   10                  15      


Phe Val His Gln Leu Ser Asp Asn Ile Tyr Pro Val Glu Asp Leu Ala 
            20                  25                  30          


Ala Thr Ser Val Thr Ile Phe Pro Asn Ala Glu Leu Gly Gly Pro Phe 
        35                  40                  45              


Asp Gln Met Asn Gly Val Ala Gly Asp Gly Met Ile Asn Ile Asp Met 
    50                  55                  60                  


Thr Gly Glu Lys Arg Ser Leu Asp Leu Pro Tyr Pro Ser Ser Phe Ala 
65                  70                  75                  80  


Pro Val Ser Ala Pro Arg Asn Gln Thr Phe Thr Tyr Met Gly Lys Phe 
                85                  90                  95      


Ser Ile Asp Pro Gln Tyr Pro Gly Ala Ser Cys Tyr Pro Glu Gly Ile 
            100                 105                 110         


Ile Asn Ile Val Ser Ala Gly Ile Leu Gln Gly Val Thr Ser Pro Ala 
        115                 120                 125             


Ser Thr Thr Ala Ser Ser Ser Val Thr Ser Ala Ser Pro Asn Pro Leu 
    130                 135                 140                 


Ala Thr Gly Pro Leu Gly Val Cys Thr Met Ser Gln Thr Gln Pro Asp 
145                 150                 155                 160 


Leu Asp His Leu Tyr Ser Pro Pro Pro Pro Pro Pro Pro Tyr Ser Gly 
                165                 170                 175     


Cys Ala Gly Asp Leu Tyr Gln Asp Pro Ser Ala Phe Leu Ser Ala Ala 
            180                 185                 190         


Thr Thr Ser Thr Ser Ser Ser Leu Ala Tyr Pro Pro Pro Pro Ser Tyr 
        195                 200                 205             


Pro Ser Pro Lys Pro Ala Thr Asp Pro Gly Leu Phe Pro Met Ile Pro 
    210                 215                 220                 


Asp Tyr Pro Gly Phe Phe Pro Ser Gln Cys Gln Arg Asp Leu His Gly 
225                 230                 235                 240 


Thr Ala Gly Pro Asp Arg Lys Pro Phe Pro Cys Pro Leu Asp Thr Leu 
                245                 250                 255     


Arg Val Pro Pro Pro Leu Thr Pro Leu Ser Thr Ile Arg Asn Phe Thr 
            260                 265                 270         


Leu Gly Gly Pro Ser Ala Gly Val Thr Gly Pro Gly Ala Ser Gly Gly 
        275                 280                 285             


Ser Glu Gly Pro Arg Leu Pro Gly Ser Ser Ser Ala Ala Ala Ala Ala 
    290                 295                 300                 


Ala Ala Ala Ala Ala Tyr Asn Pro His His Leu Pro Leu Arg Pro Ile 
305                 310                 315                 320 


Leu Arg Pro Arg Lys Tyr Pro Asn Arg Pro Ser Lys Thr Pro Val His 
                325                 330                 335     


Glu Arg Pro Tyr Pro Cys Pro Ala Glu Gly Cys Asp Arg Arg Phe Ser 
            340                 345                 350         


Arg Ser Asp Glu Leu Thr Arg His Ile Arg Ile His Thr Gly His Lys 
        355                 360                 365             


Pro Phe Gln Cys Arg Ile Cys Met Arg Asn Phe Ser Arg Ser Asp His 
    370                 375                 380                 


Leu Thr Thr His Ile Arg Thr His Thr Gly Glu Lys Pro Phe Ala Cys 
385                 390                 395                 400 


Asp Tyr Cys Gly Arg Lys Phe Ala Arg Ser Asp Glu Arg Lys Arg His 
                405                 410                 415     


Thr Lys Ile His Leu Arg Gln Lys Glu Arg Lys Ser Ser Ala Pro Ser 
            420                 425                 430         


Ala Ser Val Pro Ala Pro Ser Thr Ala Ser Cys Ser Gly Gly Val Gln 
        435                 440                 445             


Pro Gly Gly Thr Leu Cys Ser Ser Asn Ser Ser Ser Leu Gly Gly Gly 
    450                 455                 460                 


Pro Leu Ala Pro Cys Ser Ser Arg Thr Arg Thr Pro 
465                 470                 475     


<210>  3317
<211>  426
<212>  PRT
<213>  homo sapiens

<400>  3317

Met Asn Gly Val Ala Gly Asp Gly Met Ile Asn Ile Asp Met Thr Gly 
1               5                   10                  15      


Glu Lys Arg Ser Leu Asp Leu Pro Tyr Pro Ser Ser Phe Ala Pro Val 
            20                  25                  30          


Ser Ala Pro Arg Asn Gln Thr Phe Thr Tyr Met Gly Lys Phe Ser Ile 
        35                  40                  45              


Asp Pro Gln Tyr Pro Gly Ala Ser Cys Tyr Pro Glu Gly Ile Ile Asn 
    50                  55                  60                  


Ile Val Ser Ala Gly Ile Leu Gln Gly Val Thr Ser Pro Ala Ser Thr 
65                  70                  75                  80  


Thr Ala Ser Ser Ser Val Thr Ser Ala Ser Pro Asn Pro Leu Ala Thr 
                85                  90                  95      


Gly Pro Leu Gly Val Cys Thr Met Ser Gln Thr Gln Pro Asp Leu Asp 
            100                 105                 110         


His Leu Tyr Ser Pro Pro Pro Pro Pro Pro Pro Tyr Ser Gly Cys Ala 
        115                 120                 125             


Gly Asp Leu Tyr Gln Asp Pro Ser Ala Phe Leu Ser Ala Ala Thr Thr 
    130                 135                 140                 


Ser Thr Ser Ser Ser Leu Ala Tyr Pro Pro Pro Pro Ser Tyr Pro Ser 
145                 150                 155                 160 


Pro Lys Pro Ala Thr Asp Pro Gly Leu Phe Pro Met Ile Pro Asp Tyr 
                165                 170                 175     


Pro Gly Phe Phe Pro Ser Gln Cys Gln Arg Asp Leu His Gly Thr Ala 
            180                 185                 190         


Gly Pro Asp Arg Lys Pro Phe Pro Cys Pro Leu Asp Thr Leu Arg Val 
        195                 200                 205             


Pro Pro Pro Leu Thr Pro Leu Ser Thr Ile Arg Asn Phe Thr Leu Gly 
    210                 215                 220                 


Gly Pro Ser Ala Gly Val Thr Gly Pro Gly Ala Ser Gly Gly Ser Glu 
225                 230                 235                 240 


Gly Pro Arg Leu Pro Gly Ser Ser Ser Ala Ala Ala Ala Ala Ala Ala 
                245                 250                 255     


Ala Ala Ala Tyr Asn Pro His His Leu Pro Leu Arg Pro Ile Leu Arg 
            260                 265                 270         


Pro Arg Lys Tyr Pro Asn Arg Pro Ser Lys Thr Pro Val His Glu Arg 
        275                 280                 285             


Pro Tyr Pro Cys Pro Ala Glu Gly Cys Asp Arg Arg Phe Ser Arg Ser 
    290                 295                 300                 


Asp Glu Leu Thr Arg His Ile Arg Ile His Thr Gly His Lys Pro Phe 
305                 310                 315                 320 


Gln Cys Arg Ile Cys Met Arg Asn Phe Ser Arg Ser Asp His Leu Thr 
                325                 330                 335     


Thr His Ile Arg Thr His Thr Gly Glu Lys Pro Phe Ala Cys Asp Tyr 
            340                 345                 350         


Cys Gly Arg Lys Phe Ala Arg Ser Asp Glu Arg Lys Arg His Thr Lys 
        355                 360                 365             


Ile His Leu Arg Gln Lys Glu Arg Lys Ser Ser Ala Pro Ser Ala Ser 
    370                 375                 380                 


Val Pro Ala Pro Ser Thr Ala Ser Cys Ser Gly Gly Val Gln Pro Gly 
385                 390                 395                 400 


Gly Thr Leu Cys Ser Ser Asn Ser Ser Ser Leu Gly Gly Gly Pro Leu 
                405                 410                 415     


Ala Pro Cys Ser Ser Arg Thr Arg Thr Pro 
            420                 425     


<210>  3318
<211>  416
<212>  PRT
<213>  homo sapiens

<400>  3318

Met Ala His Ser Pro Val Ala Val Gln Val Pro Gly Met Gln Asn Asn 
1               5                   10                  15      


Ile Ala Asp Pro Glu Glu Leu Phe Thr Lys Leu Glu Arg Ile Gly Lys 
            20                  25                  30          


Gly Ser Phe Gly Glu Val Phe Lys Gly Ile Asp Asn Arg Thr Gln Gln 
        35                  40                  45              


Val Val Ala Ile Lys Ile Ile Asp Leu Glu Glu Ala Glu Asp Glu Ile 
    50                  55                  60                  


Glu Asp Ile Gln Gln Glu Ile Thr Val Leu Ser Gln Cys Asp Ser Ser 
65                  70                  75                  80  


Tyr Val Thr Lys Tyr Tyr Gly Ser Tyr Leu Lys Gly Ser Lys Leu Trp 
                85                  90                  95      


Ile Ile Met Glu Tyr Leu Gly Gly Gly Ser Ala Leu Asp Leu Leu Arg 
            100                 105                 110         


Ala Gly Pro Phe Asp Glu Phe Gln Ile Ala Thr Met Leu Lys Glu Ile 
        115                 120                 125             


Leu Lys Gly Leu Asp Tyr Leu His Ser Glu Lys Lys Ile His Arg Asp 
    130                 135                 140                 


Ile Lys Ala Ala Asn Val Leu Leu Ser Glu Gln Gly Asp Val Lys Leu 
145                 150                 155                 160 


Ala Asp Phe Gly Val Ala Gly Gln Leu Thr Asp Thr Gln Ile Lys Arg 
                165                 170                 175     


Asn Thr Phe Val Gly Thr Pro Phe Trp Met Ala Pro Glu Val Ile Gln 
            180                 185                 190         


Gln Ser Ala Tyr Asp Ser Lys Ala Asp Ile Trp Ser Leu Gly Ile Thr 
        195                 200                 205             


Ala Ile Glu Leu Ala Lys Gly Glu Pro Pro Asn Ser Asp Met His Pro 
    210                 215                 220                 


Met Arg Val Leu Phe Leu Ile Pro Lys Asn Asn Pro Pro Thr Leu Val 
225                 230                 235                 240 


Gly Asp Phe Thr Lys Ser Phe Lys Glu Phe Ile Asp Ala Cys Leu Asn 
                245                 250                 255     


Lys Asp Pro Ser Phe Arg Pro Thr Ala Lys Glu Leu Leu Lys His Lys 
            260                 265                 270         


Phe Ile Val Lys Asn Ser Lys Lys Thr Ser Tyr Leu Thr Glu Leu Ile 
        275                 280                 285             


Asp Arg Phe Lys Arg Trp Lys Ala Glu Gly His Ser Asp Asp Glu Ser 
    290                 295                 300                 


Asp Ser Glu Gly Ser Asp Ser Glu Ser Thr Ser Arg Glu Asn Asn Thr 
305                 310                 315                 320 


His Pro Glu Trp Ser Phe Thr Thr Val Arg Lys Lys Pro Asp Pro Lys 
                325                 330                 335     


Lys Val Gln Asn Gly Ala Glu Gln Asp Leu Val Gln Thr Leu Ser Cys 
            340                 345                 350         


Leu Ser Met Ile Ile Thr Pro Ala Phe Ala Glu Leu Lys Gln Gln Asp 
        355                 360                 365             


Glu Asn Asn Ala Ser Arg Asn Gln Ala Ile Glu Glu Leu Glu Lys Ser 
    370                 375                 380                 


Ile Ala Val Ala Glu Ala Ala Cys Pro Gly Ile Thr Asp Lys Met Val 
385                 390                 395                 400 


Lys Lys Leu Ile Glu Lys Phe Gln Lys Cys Ser Ala Asp Glu Ser Pro 
                405                 410                 415     


<210>  3319
<211>  686
<212>  PRT
<213>  homo sapiens

<400>  3319

Met Asn Pro Thr Glu Thr Lys Ala Val Lys Thr Glu Pro Glu Lys Lys 
1               5                   10                  15      


Ser Gln Ser Thr Lys Leu Ser Val Val His Glu Lys Lys Ser Gln Glu 
            20                  25                  30          


Gly Lys Pro Lys Glu His Thr Glu Pro Lys Ser Leu Pro Lys Gln Ala 
        35                  40                  45              


Ser Asp Thr Gly Ser Asn Asp Ala His Asn Lys Lys Ala Val Ser Arg 
    50                  55                  60                  


Ser Ala Glu Gln Gln Pro Ser Glu Lys Ser Thr Glu Pro Lys Thr Lys 
65                  70                  75                  80  


Pro Gln Asp Met Ile Ser Ala Gly Gly Glu Ser Val Ala Gly Ile Thr 
                85                  90                  95      


Ala Ile Ser Gly Lys Pro Gly Asp Lys Lys Lys Glu Lys Lys Ser Leu 
            100                 105                 110         


Thr Pro Ala Val Pro Val Glu Ser Lys Pro Asp Lys Pro Ser Gly Lys 
        115                 120                 125             


Ser Gly Met Asp Ala Ala Leu Asp Asp Leu Ile Asp Thr Leu Gly Gly 
    130                 135                 140                 


Pro Glu Glu Thr Glu Glu Glu Asn Thr Thr Tyr Thr Gly Pro Glu Val 
145                 150                 155                 160 


Ser Asp Pro Met Ser Ser Thr Tyr Ile Glu Glu Leu Gly Lys Arg Glu 
                165                 170                 175     


Val Thr Ile Pro Pro Lys Tyr Arg Glu Leu Leu Ala Lys Lys Glu Gly 
            180                 185                 190         


Ile Thr Gly Pro Pro Ala Asp Ser Ser Lys Pro Ile Gly Pro Asp Asp 
        195                 200                 205             


Ala Ile Asp Ala Leu Ser Ser Asp Phe Thr Cys Gly Ser Pro Thr Ala 
    210                 215                 220                 


Ala Gly Lys Lys Thr Glu Lys Glu Glu Ser Thr Glu Val Leu Lys Ala 
225                 230                 235                 240 


Gln Ser Ala Gly Thr Val Arg Ser Ala Ala Pro Pro Gln Glu Lys Lys 
                245                 250                 255     


Arg Lys Val Glu Lys Asp Thr Met Ser Asp Gln Ala Leu Glu Ala Leu 
            260                 265                 270         


Ser Ala Ser Leu Gly Thr Arg Gln Ala Glu Pro Glu Leu Asp Leu Arg 
        275                 280                 285             


Ser Ile Lys Glu Val Asp Glu Ala Lys Ala Lys Glu Glu Lys Leu Glu 
    290                 295                 300                 


Lys Cys Gly Glu Asp Asp Glu Thr Ile Pro Ser Glu Tyr Arg Leu Lys 
305                 310                 315                 320 


Pro Ala Thr Asp Lys Asp Gly Lys Pro Leu Leu Pro Glu Pro Glu Glu 
                325                 330                 335     


Lys Pro Lys Pro Arg Ser Glu Ser Glu Leu Ile Asp Glu Leu Ser Glu 
            340                 345                 350         


Asp Phe Asp Arg Ser Glu Cys Lys Glu Lys Pro Ser Lys Pro Thr Glu 
        355                 360                 365             


Lys Thr Glu Glu Ser Lys Ala Ala Ala Pro Ala Pro Val Ser Glu Ala 
    370                 375                 380                 


Val Cys Arg Thr Ser Met Cys Ser Ile Gln Ser Ala Pro Pro Glu Pro 
385                 390                 395                 400 


Ala Thr Leu Lys Gly Thr Val Pro Asp Asp Ala Val Glu Ala Leu Ala 
                405                 410                 415     


Asp Ser Leu Gly Lys Lys Glu Ala Asp Pro Glu Asp Gly Lys Pro Val 
            420                 425                 430         


Met Asp Lys Val Lys Glu Lys Ala Lys Glu Glu Asp Arg Glu Lys Leu 
        435                 440                 445             


Gly Glu Lys Glu Glu Thr Ile Pro Pro Asp Tyr Arg Leu Glu Glu Val 
    450                 455                 460                 


Lys Asp Lys Asp Gly Lys Pro Leu Leu Pro Lys Glu Ser Lys Glu Gln 
465                 470                 475                 480 


Leu Pro Pro Met Ser Glu Asp Phe Leu Leu Asp Ala Leu Ser Glu Asp 
                485                 490                 495     


Phe Ser Gly Pro Gln Asn Ala Ser Ser Leu Lys Phe Glu Asp Ala Lys 
            500                 505                 510         


Leu Ala Ala Ala Ile Ser Glu Val Val Ser Gln Thr Pro Ala Ser Thr 
        515                 520                 525             


Thr Gln Ala Gly Ala Pro Pro Arg Asp Thr Ser Gln Ser Asp Lys Asp 
    530                 535                 540                 


Leu Asp Asp Ala Leu Asp Lys Leu Ser Asp Ser Leu Gly Gln Arg Gln 
545                 550                 555                 560 


Pro Asp Pro Asp Glu Asn Lys Pro Met Glu Asp Lys Val Lys Glu Lys 
                565                 570                 575     


Ala Lys Ala Glu His Arg Asp Lys Leu Gly Glu Arg Asp Asp Thr Ile 
            580                 585                 590         


Pro Pro Glu Tyr Arg His Leu Leu Asp Asp Asn Gly Gln Asp Lys Pro 
        595                 600                 605             


Val Lys Pro Pro Thr Lys Lys Ser Glu Asp Ser Lys Lys Pro Ala Asp 
    610                 615                 620                 


Asp Gln Asp Pro Ile Asp Ala Leu Ser Gly Asp Leu Asp Ser Cys Pro 
625                 630                 635                 640 


Ser Thr Thr Glu Thr Ser Gln Asn Thr Ala Lys Asp Lys Cys Lys Lys 
                645                 650                 655     


Ala Ala Ser Ser Ser Lys Ala Pro Lys Asn Gly Gly Lys Ala Lys Asp 
            660                 665                 670         


Ser Ala Lys Thr Thr Glu Glu Thr Ser Lys Pro Lys Asp Asp 
        675                 680                 685     


<210>  3320
<211>  185
<212>  PRT
<213>  homo sapiens

<400>  3320

Met Val Lys Leu Gly Asn Asn Phe Ala Glu Lys Gly Thr Lys Gln Pro 
1               5                   10                  15      


Leu Leu Glu Asp Gly Phe Asp Thr Ile Pro Leu Met Thr Pro Leu Asp 
            20                  25                  30          


Val Asn Gln Leu Gln Phe Pro Pro Pro Asp Lys Val Val Val Lys Thr 
        35                  40                  45              


Lys Thr Glu Tyr Glu Pro Asp Arg Lys Lys Gly Lys Ala Arg Pro Pro 
    50                  55                  60                  


Gln Ile Ala Glu Phe Thr Val Ser Ile Thr Glu Gly Val Thr Glu Arg 
65                  70                  75                  80  


Phe Lys Val Ser Val Leu Val Leu Phe Ala Leu Ala Phe Leu Thr Cys 
                85                  90                  95      


Val Val Phe Leu Val Val Tyr Lys Val Tyr Lys Tyr Asp Arg Ala Cys 
            100                 105                 110         


Pro Asp Gly Phe Val Leu Lys Asn Thr Gln Cys Ile Pro Glu Gly Leu 
        115                 120                 125             


Glu Ser Tyr Tyr Ala Glu Gln Asp Ser Ser Ala Arg Glu Lys Phe Tyr 
    130                 135                 140                 


Thr Val Ile Asn His Tyr Asn Leu Ala Lys Gln Ser Ile Thr Arg Ser 
145                 150                 155                 160 


Val Ser Pro Trp Met Ser Val Leu Ser Glu Glu Lys Leu Ser Glu Gln 
                165                 170                 175     


Glu Thr Glu Ala Ala Glu Lys Ser Ala 
            180                 185 


<210>  3321
<211>  598
<212>  PRT
<213>  homo sapiens

<400>  3321

Met Pro Cys Ile Gln Ala Gln Tyr Gly Thr Pro Ala Pro Ser Pro Gly 
1               5                   10                  15      


Pro Arg Asp His Leu Ala Ser Asp Pro Leu Thr Pro Glu Phe Ile Lys 
            20                  25                  30          


Pro Thr Met Asp Leu Ala Ser Pro Glu Ala Ala Pro Ala Ala Pro Thr 
        35                  40                  45              


Ala Leu Pro Ser Phe Ser Thr Phe Met Asp Gly Tyr Thr Gly Glu Phe 
    50                  55                  60                  


Asp Thr Phe Leu Tyr Gln Leu Pro Gly Thr Val Gln Pro Cys Ser Ser 
65                  70                  75                  80  


Ala Ser Ser Ser Ala Ser Ser Thr Ser Ser Ser Ser Ala Thr Ser Pro 
                85                  90                  95      


Ala Ser Ala Ser Phe Lys Phe Glu Asp Phe Gln Val Tyr Gly Cys Tyr 
            100                 105                 110         


Pro Gly Pro Leu Ser Gly Pro Val Asp Glu Ala Leu Ser Ser Ser Gly 
        115                 120                 125             


Ser Asp Tyr Tyr Gly Ser Pro Cys Ser Ala Pro Ser Pro Ser Thr Pro 
    130                 135                 140                 


Ser Phe Gln Pro Pro Gln Leu Ser Pro Trp Asp Gly Ser Phe Gly His 
145                 150                 155                 160 


Phe Ser Pro Ser Gln Thr Tyr Glu Gly Leu Arg Ala Trp Thr Glu Gln 
                165                 170                 175     


Leu Pro Lys Ala Ser Gly Pro Pro Gln Pro Pro Ala Phe Phe Ser Phe 
            180                 185                 190         


Ser Pro Pro Thr Gly Pro Ser Pro Ser Leu Ala Gln Ser Pro Leu Lys 
        195                 200                 205             


Leu Phe Pro Ser Gln Ala Thr His Gln Leu Gly Glu Gly Glu Ser Tyr 
    210                 215                 220                 


Ser Met Pro Thr Ala Phe Pro Gly Leu Ala Pro Thr Ser Pro His Leu 
225                 230                 235                 240 


Glu Gly Ser Gly Ile Leu Asp Thr Pro Val Thr Ser Thr Lys Ala Arg 
                245                 250                 255     


Ser Gly Ala Pro Gly Gly Ser Glu Gly Arg Cys Ala Val Cys Gly Asp 
            260                 265                 270         


Asn Ala Ser Cys Gln His Tyr Gly Val Arg Thr Cys Glu Gly Cys Lys 
        275                 280                 285             


Gly Phe Phe Lys Arg Thr Val Gln Lys Asn Ala Lys Tyr Ile Cys Leu 
    290                 295                 300                 


Ala Asn Lys Asp Cys Pro Val Asp Lys Arg Arg Arg Asn Arg Cys Gln 
305                 310                 315                 320 


Phe Cys Arg Phe Gln Lys Cys Leu Ala Val Gly Met Val Lys Glu Val 
                325                 330                 335     


Val Arg Thr Asp Ser Leu Lys Gly Arg Arg Gly Arg Leu Pro Ser Lys 
            340                 345                 350         


Pro Lys Gln Pro Pro Asp Ala Ser Pro Ala Asn Leu Leu Thr Ser Leu 
        355                 360                 365             


Val Arg Ala His Leu Asp Ser Gly Pro Ser Thr Ala Lys Leu Asp Tyr 
    370                 375                 380                 


Ser Lys Phe Gln Glu Leu Val Leu Pro His Phe Gly Lys Glu Asp Ala 
385                 390                 395                 400 


Gly Asp Val Gln Gln Phe Tyr Asp Leu Leu Ser Gly Ser Leu Glu Val 
                405                 410                 415     


Ile Arg Lys Trp Ala Glu Lys Ile Pro Gly Phe Ala Glu Leu Ser Pro 
            420                 425                 430         


Ala Asp Gln Asp Leu Leu Leu Glu Ser Ala Phe Leu Glu Leu Phe Ile 
        435                 440                 445             


Leu Arg Leu Ala Tyr Arg Ser Lys Pro Gly Glu Gly Lys Leu Ile Phe 
    450                 455                 460                 


Cys Ser Gly Leu Val Leu His Arg Leu Gln Cys Ala Arg Gly Phe Gly 
465                 470                 475                 480 


Asp Trp Ile Asp Ser Ile Leu Ala Phe Ser Arg Ser Leu His Ser Leu 
                485                 490                 495     


Leu Val Asp Val Pro Ala Phe Ala Cys Leu Ser Ala Leu Val Leu Ile 
            500                 505                 510         


Thr Asp Arg His Gly Leu Gln Glu Pro Arg Arg Val Glu Glu Leu Gln 
        515                 520                 525             


Asn Arg Ile Ala Ser Cys Leu Lys Glu His Val Ala Ala Val Ala Gly 
    530                 535                 540                 


Glu Pro Gln Pro Ala Ser Cys Leu Ser Arg Leu Leu Gly Lys Leu Pro 
545                 550                 555                 560 


Glu Leu Arg Thr Leu Cys Thr Gln Gly Leu Gln Arg Ile Phe Tyr Leu 
                565                 570                 575     


Lys Leu Glu Asp Leu Val Pro Pro Pro Pro Ile Ile Asp Lys Ile Phe 
            580                 585                 590         


Met Asp Thr Leu Pro Phe 
        595             


<210>  3322
<211>  334
<212>  PRT
<213>  homo sapiens

<400>  3322

Met Arg Tyr Lys Thr Ser Leu Val Met Arg Lys Arg Leu Arg Leu Tyr 
1               5                   10                  15      


Arg Asn Thr Leu Lys Glu Ser Ser Ser Ser Ser Gly His His Gly Pro 
            20                  25                  30          


Gln Leu Thr Ala Ala Ser Ser Pro Ser Val Phe Pro Gly Leu His Glu 
        35                  40                  45              


Glu Pro Pro Gln Ala Ser Pro Ser Arg Pro Leu Asn Gly Leu Leu Arg 
    50                  55                  60                  


Leu Gly Leu Pro Gly Asp Met Tyr Ala Arg Pro Glu Pro Phe Pro Pro 
65                  70                  75                  80  


Gly Pro Ala Ala Arg Ser Asp Ala Leu Ala Ala Ala Ala Ala Leu His 
                85                  90                  95      


Gly Tyr Gly Gly Met Asn Leu Thr Val Asn Leu Ala Ala Pro His Gly 
            100                 105                 110         


Pro Gly Ala Phe Phe Arg Tyr Met Arg Gln Pro Ile Lys Gln Glu Leu 
        115                 120                 125             


Ile Cys Lys Trp Leu Ala Ala Asp Gly Thr Ala Thr Pro Ser Leu Cys 
    130                 135                 140                 


Ser Lys Thr Phe Ser Thr Met His Glu Leu Val Thr His Val Thr Val 
145                 150                 155                 160 


Glu His Val Gly Gly Pro Glu Gln Ala Asn His Ile Cys Phe Trp Glu 
                165                 170                 175     


Glu Cys Pro Arg Gln Gly Lys Pro Phe Lys Ala Lys Tyr Lys Leu Val 
            180                 185                 190         


Asn His Ile Arg Val His Thr Gly Glu Lys Pro Phe Pro Cys Pro Phe 
        195                 200                 205             


Pro Gly Cys Gly Lys Val Phe Ala Arg Ser Glu Asn Leu Lys Ile His 
    210                 215                 220                 


Lys Arg Thr His Thr Gly Glu Lys Pro Phe Arg Cys Glu Phe Glu Gly 
225                 230                 235                 240 


Cys Glu Arg Arg Phe Ala Asn Ser Ser Asp Arg Lys Lys His Ser His 
                245                 250                 255     


Val His Thr Ser Asp Lys Pro Tyr Thr Cys Lys Val Arg Gly Cys Asp 
            260                 265                 270         


Lys Cys Tyr Thr His Pro Ser Ser Leu Arg Lys His Met Lys Val His 
        275                 280                 285             


Gly Arg Ser Pro Pro Pro Ser Ser Gly Tyr Asp Ser Ala Thr Pro Ser 
    290                 295                 300                 


Ala Leu Val Ser Pro Ser Ser Asp Cys Gly His Lys Ser Gln Val Ala 
305                 310                 315                 320 


Ser Ser Ala Ala Val Ala Ala Arg Thr Ala Asp Leu Ser Glu 
                325                 330                 


<210>  3323
<211>  612
<212>  PRT
<213>  homo sapiens

<400>  3323

Met Lys Ala Thr Trp Ile Arg Leu Leu Lys Arg Ala Lys Gly Gly Arg 
1               5                   10                  15      


Leu Lys Asn Ser Asp Ile Cys Gly Ser Ala Asp Ser Tyr Thr Ser Arg 
            20                  25                  30          


Pro Ser Asp Ser Asp Val Ser Leu Glu Glu Asp Arg Glu Ala Val Arg 
        35                  40                  45              


Arg Glu Ala Glu Arg Gln Ala Gln Ala Gln Leu Glu Lys Ala Lys Thr 
    50                  55                  60                  


Lys Pro Val Ala Phe Ala Val Arg Thr Asn Val Ser Tyr Ser Ala Ala 
65                  70                  75                  80  


His Glu Asp Asp Val Pro Val Pro Gly Met Ala Ile Ser Phe Glu Ala 
                85                  90                  95      


Lys Asp Phe Leu His Val Lys Glu Lys Phe Asn Asn Asp Trp Trp Ile 
            100                 105                 110         


Gly Arg Leu Val Lys Glu Gly Cys Glu Ile Gly Phe Ile Pro Ser Pro 
        115                 120                 125             


Val Lys Leu Glu Asn Met Arg Leu Gln His Glu Gln Arg Ala Lys Gln 
    130                 135                 140                 


Gly Lys Phe Tyr Ser Ser Lys Ser Gly Gly Asn Ser Ser Ser Ser Leu 
145                 150                 155                 160 


Gly Asp Ile Val Pro Ser Ser Arg Lys Ser Thr Pro Pro Ser Ser Ala 
                165                 170                 175     


Ile Asp Ile Asp Ala Thr Gly Leu Asp Ala Glu Glu Asn Asp Ile Pro 
            180                 185                 190         


Ala Asn His Arg Ser Pro Lys Pro Ser Ala Asn Ser Val Thr Ser Pro 
        195                 200                 205             


His Ser Lys Glu Lys Arg Met Pro Phe Phe Lys Lys Thr Glu His Thr 
    210                 215                 220                 


Pro Pro Tyr Asp Val Val Pro Ser Met Arg Pro Val Val Leu Val Gly 
225                 230                 235                 240 


Pro Ser Leu Lys Gly Tyr Glu Val Thr Asp Met Met Gln Lys Ala Leu 
                245                 250                 255     


Phe Asp Phe Leu Lys His Arg Phe Glu Gly Arg Ile Ser Ile Thr Arg 
            260                 265                 270         


Val Thr Ala Asp Ile Ser Leu Ala Lys Arg Ser Val Leu Asn Asn Pro 
        275                 280                 285             


Ser Lys His Ala Ile Ile Glu Arg Ser Asn Thr Arg Ser Ser Leu Ala 
    290                 295                 300                 


Glu Val Gln Ser Glu Ile Glu Arg Ile Phe Glu Leu Ala Arg Thr Leu 
305                 310                 315                 320 


Gln Leu Val Val Leu Asp Ala Asp Thr Ile Asn His Pro Ala Gln Leu 
                325                 330                 335     


Ser Lys Thr Ser Leu Ala Pro Ile Ile Val Tyr Val Lys Ile Ser Ser 
            340                 345                 350         


Pro Lys Val Leu Gln Arg Leu Ile Lys Ser Arg Gly Lys Ser Gln Ala 
        355                 360                 365             


Lys His Leu Asn Val Gln Met Val Ala Ala Asp Lys Leu Ala Gln Cys 
    370                 375                 380                 


Pro Pro Glu Leu Phe Asp Val Ile Leu Asp Glu Asn Gln Leu Glu Asp 
385                 390                 395                 400 


Ala Cys Glu His Leu Ala Asp Tyr Leu Glu Ala Tyr Trp Lys Ala Thr 
                405                 410                 415     


His Pro Pro Ser Ser Ser Leu Pro Asn Pro Leu Leu Ser Arg Thr Leu 
            420                 425                 430         


Ala Thr Ser Ser Leu Pro Leu Ser Pro Thr Leu Ala Ser Asn Ser Gln 
        435                 440                 445             


Gly Ser Gln Gly Asp Gln Arg Thr Asp Arg Ser Ala Pro Ile Arg Ser 
    450                 455                 460                 


Ala Ser Gln Ala Glu Glu Glu Pro Ser Val Glu Pro Val Lys Lys Ser 
465                 470                 475                 480 


Gln His Arg Ser Ser Ser Ser Ala Pro His His Asn His Arg Ser Gly 
                485                 490                 495     


Thr Ser Arg Gly Leu Ser Arg Gln Glu Thr Phe Asp Ser Glu Thr Gln 
            500                 505                 510         


Glu Ser Arg Asp Ser Ala Tyr Val Glu Pro Lys Glu Asp Tyr Ser His 
        515                 520                 525             


Asp His Val Asp His Tyr Ala Ser His Arg Asp His Asn His Arg Asp 
    530                 535                 540                 


Glu Thr His Gly Ser Ser Asp His Arg His Arg Glu Ser Arg His Arg 
545                 550                 555                 560 


Ser Arg Asp Val Asp Arg Glu Gln Asp His Asn Glu Cys Asn Lys Gln 
                565                 570                 575     


Arg Ser Arg His Lys Ser Lys Asp Arg Tyr Cys Glu Lys Asp Gly Glu 
            580                 585                 590         


Val Ile Ser Lys Lys Arg Asn Glu Ala Gly Glu Trp Asn Arg Asp Val 
        595                 600                 605             


Tyr Ile Arg Gln 
    610         


<210>  3324
<211>  986
<212>  PRT
<213>  homo sapiens

<400>  3324

Met Asp Leu Lys Glu Gln Pro Gly Asn Thr Ile Ser Ala Gly Gln Glu 
1               5                   10                  15      


Asp Phe Pro Ser Val Leu Leu Glu Thr Ala Ala Ser Leu Pro Ser Leu 
            20                  25                  30          


Ser Pro Leu Ser Ala Ala Ser Phe Lys Glu His Glu Tyr Leu Gly Asn 
        35                  40                  45              


Leu Ser Thr Val Leu Pro Thr Glu Gly Thr Leu Gln Glu Asn Val Ser 
    50                  55                  60                  


Glu Ala Ser Lys Glu Val Ser Glu Lys Ala Lys Thr Leu Leu Ile Asp 
65                  70                  75                  80  


Arg Asp Leu Thr Glu Phe Ser Glu Leu Glu Tyr Ser Glu Met Gly Ser 
                85                  90                  95      


Ser Phe Ser Val Ser Pro Lys Ala Glu Ser Ala Val Ile Val Ala Asn 
            100                 105                 110         


Pro Arg Glu Glu Ile Ile Val Lys Asn Lys Asp Glu Glu Glu Lys Leu 
        115                 120                 125             


Val Ser Asn Asn Ile Leu His Asn Gln Gln Glu Leu Pro Thr Ala Leu 
    130                 135                 140                 


Thr Lys Leu Val Lys Glu Asp Glu Val Val Ser Ser Glu Lys Ala Lys 
145                 150                 155                 160 


Asp Ser Phe Asn Glu Lys Arg Val Ala Val Glu Ala Pro Met Arg Glu 
                165                 170                 175     


Glu Tyr Ala Asp Phe Lys Pro Phe Glu Arg Val Trp Glu Val Lys Asp 
            180                 185                 190         


Ser Lys Glu Asp Ser Asp Met Leu Ala Ala Gly Gly Lys Ile Glu Ser 
        195                 200                 205             


Asn Leu Glu Ser Lys Val Asp Lys Lys Cys Phe Ala Asp Ser Leu Glu 
    210                 215                 220                 


Gln Thr Asn His Glu Lys Asp Ser Glu Ser Ser Asn Asp Asp Thr Ser 
225                 230                 235                 240 


Phe Pro Ser Thr Pro Glu Gly Ile Lys Asp Arg Ser Gly Ala Tyr Ile 
                245                 250                 255     


Thr Cys Ala Pro Phe Asn Pro Ala Ala Thr Glu Ser Ile Ala Thr Asn 
            260                 265                 270         


Ile Phe Pro Leu Leu Gly Asp Pro Thr Ser Glu Asn Lys Thr Asp Glu 
        275                 280                 285             


Lys Lys Ile Glu Glu Lys Lys Ala Gln Ile Val Thr Glu Lys Asn Thr 
    290                 295                 300                 


Ser Thr Lys Thr Ser Asn Pro Phe Leu Val Ala Ala Gln Asp Ser Glu 
305                 310                 315                 320 


Thr Asp Tyr Val Thr Thr Asp Asn Leu Thr Lys Val Thr Glu Glu Val 
                325                 330                 335     


Val Ala Asn Met Pro Glu Gly Leu Thr Pro Asp Leu Val Gln Glu Ala 
            340                 345                 350         


Cys Glu Ser Glu Leu Asn Glu Val Thr Gly Thr Lys Ile Ala Tyr Glu 
        355                 360                 365             


Thr Lys Met Asp Leu Val Gln Thr Ser Glu Val Met Gln Glu Ser Leu 
    370                 375                 380                 


Tyr Pro Ala Ala Gln Leu Cys Pro Ser Phe Glu Glu Ser Glu Ala Thr 
385                 390                 395                 400 


Pro Ser Pro Val Leu Pro Asp Ile Val Met Glu Ala Pro Leu Asn Ser 
                405                 410                 415     


Ala Val Pro Ser Ala Gly Ala Ser Val Ile Gln Pro Ser Ser Ser Pro 
            420                 425                 430         


Leu Glu Ala Ser Ser Val Asn Tyr Glu Ser Ile Lys His Glu Pro Glu 
        435                 440                 445             


Asn Pro Pro Pro Tyr Glu Glu Ala Met Ser Val Ser Leu Lys Lys Val 
    450                 455                 460                 


Ser Gly Ile Lys Glu Glu Ile Lys Glu Pro Glu Asn Ile Asn Ala Ala 
465                 470                 475                 480 


Leu Gln Glu Thr Glu Ala Pro Tyr Ile Ser Ile Ala Cys Asp Leu Ile 
                485                 490                 495     


Lys Glu Thr Lys Leu Ser Ala Glu Pro Ala Pro Asp Phe Ser Asp Tyr 
            500                 505                 510         


Ser Glu Met Ala Lys Val Glu Gln Pro Val Pro Asp His Ser Glu Leu 
        515                 520                 525             


Val Glu Asp Ser Ser Pro Asp Ser Glu Pro Val Asp Leu Phe Ser Asp 
    530                 535                 540                 


Asp Ser Ile Pro Asp Val Pro Gln Lys Gln Asp Glu Thr Val Met Leu 
545                 550                 555                 560 


Val Lys Glu Ser Leu Thr Glu Thr Ser Phe Glu Ser Met Ile Glu Tyr 
                565                 570                 575     


Glu Asn Lys Glu Lys Leu Ser Ala Leu Pro Pro Glu Gly Gly Lys Pro 
            580                 585                 590         


Tyr Leu Glu Ser Phe Lys Leu Ser Leu Asp Asn Thr Lys Asp Thr Leu 
        595                 600                 605             


Leu Pro Asp Glu Val Ser Thr Leu Ser Lys Lys Glu Lys Ile Pro Leu 
    610                 615                 620                 


Gln Met Glu Glu Leu Ser Thr Ala Val Tyr Ser Asn Asp Asp Leu Phe 
625                 630                 635                 640 


Ile Ser Lys Glu Ala Gln Ile Arg Glu Thr Glu Thr Phe Ser Asp Ser 
                645                 650                 655     


Ser Pro Ile Glu Ile Ile Asp Glu Phe Pro Thr Leu Ile Ser Ser Lys 
            660                 665                 670         


Thr Asp Ser Phe Ser Lys Leu Ala Arg Glu Tyr Thr Asp Leu Glu Val 
        675                 680                 685             


Ser His Lys Ser Glu Ile Ala Asn Ala Pro Asp Gly Ala Gly Ser Leu 
    690                 695                 700                 


Pro Cys Thr Glu Leu Pro His Asp Leu Ser Leu Lys Asn Ile Gln Pro 
705                 710                 715                 720 


Lys Val Glu Glu Lys Ile Ser Phe Ser Asp Asp Phe Ser Lys Asn Gly 
                725                 730                 735     


Ser Ala Thr Ser Lys Val Leu Leu Leu Pro Pro Asp Val Ser Ala Leu 
            740                 745                 750         


Ala Thr Gln Ala Glu Ile Glu Ser Ile Val Lys Pro Lys Val Leu Val 
        755                 760                 765             


Lys Glu Ala Glu Lys Lys Leu Pro Ser Asp Thr Glu Lys Glu Asp Arg 
    770                 775                 780                 


Ser Pro Ser Ala Ile Phe Ser Ala Glu Leu Ser Lys Thr Ser Val Val 
785                 790                 795                 800 


Asp Leu Leu Tyr Trp Arg Asp Ile Lys Lys Thr Gly Val Val Phe Gly 
                805                 810                 815     


Ala Ser Leu Phe Leu Leu Leu Ser Leu Thr Val Phe Ser Ile Val Ser 
            820                 825                 830         


Val Thr Ala Tyr Ile Ala Leu Ala Leu Leu Ser Val Thr Ile Ser Phe 
        835                 840                 845             


Arg Ile Tyr Lys Gly Val Ile Gln Ala Ile Gln Lys Ser Asp Glu Gly 
    850                 855                 860                 


His Pro Phe Arg Ala Tyr Leu Glu Ser Glu Val Ala Ile Ser Glu Glu 
865                 870                 875                 880 


Leu Val Gln Lys Tyr Ser Asn Ser Ala Leu Gly His Val Asn Cys Thr 
                885                 890                 895     


Ile Lys Glu Leu Arg Arg Leu Phe Leu Val Asp Asp Leu Val Asp Ser 
            900                 905                 910         


Leu Lys Phe Ala Val Leu Met Trp Val Phe Thr Tyr Val Gly Ala Leu 
        915                 920                 925             


Phe Asn Gly Leu Thr Leu Leu Ile Leu Ala Leu Ile Ser Leu Phe Ser 
    930                 935                 940                 


Val Pro Val Ile Tyr Glu Arg His Gln Ala Gln Ile Asp His Tyr Leu 
945                 950                 955                 960 


Gly Leu Ala Asn Lys Asn Val Lys Asp Ala Met Ala Lys Ile Gln Ala 
                965                 970                 975     


Lys Ile Pro Gly Leu Lys Arg Lys Ala Glu 
            980                 985     


<210>  3325
<211>  1328
<212>  PRT
<213>  homo sapiens

<400>  3325

Met Asp Gln Lys Ile Leu Ser Leu Ala Ala Glu Lys Thr Ala Asp Lys 
1               5                   10                  15      


Leu Gln Glu Phe Leu Gln Thr Leu Arg Glu Gly Asp Leu Thr Asn Leu 
            20                  25                  30          


Leu Gln Asn Gln Ala Val Lys Gly Lys Val Ala Gly Ala Leu Leu Arg 
        35                  40                  45              


Ala Ile Phe Lys Gly Ser Pro Cys Ser Glu Glu Ala Gly Thr Leu Arg 
    50                  55                  60                  


Arg Arg Lys Ile Tyr Thr Cys Cys Ile Gln Leu Val Glu Ser Gly Asp 
65                  70                  75                  80  


Leu Gln Lys Glu Ile Ala Ser Glu Ile Ile Gly Leu Leu Met Leu Glu 
                85                  90                  95      


Ala His His Phe Pro Gly Pro Leu Leu Val Glu Leu Ala Asn Glu Phe 
            100                 105                 110         


Ile Ser Ala Val Arg Glu Gly Ser Leu Val Asn Gly Lys Ser Leu Glu 
        115                 120                 125             


Leu Leu Pro Ile Ile Leu Thr Ala Leu Ala Thr Lys Lys Glu Asn Leu 
    130                 135                 140                 


Ala Tyr Gly Lys Gly Val Leu Ser Gly Glu Glu Cys Lys Lys Gln Leu 
145                 150                 155                 160 


Ile Asn Thr Leu Cys Ser Gly Arg Trp Asp Gln Gln Tyr Val Ile Gln 
                165                 170                 175     


Leu Thr Ser Met Phe Lys Asp Val Pro Leu Thr Ala Glu Glu Val Glu 
            180                 185                 190         


Phe Val Val Glu Lys Ala Leu Ser Met Phe Ser Lys Met Asn Leu Gln 
        195                 200                 205             


Glu Ile Pro Pro Leu Val Tyr Gln Leu Leu Val Leu Ser Ser Lys Gly 
    210                 215                 220                 


Ser Arg Lys Ser Val Leu Glu Gly Ile Ile Ala Phe Phe Ser Ala Leu 
225                 230                 235                 240 


Asp Lys Gln His Asn Glu Glu Gln Ser Gly Asp Glu Leu Leu Asp Val 
                245                 250                 255     


Val Thr Val Pro Ser Gly Glu Leu Arg His Val Glu Gly Thr Ile Ile 
            260                 265                 270         


Leu His Ile Val Phe Ala Ile Lys Leu Asp Tyr Glu Leu Gly Arg Glu 
        275                 280                 285             


Leu Val Lys His Leu Lys Val Gly Gln Gln Gly Asp Ser Asn Asn Asn 
    290                 295                 300                 


Leu Ser Pro Phe Ser Ile Ala Leu Leu Leu Ser Val Thr Arg Ile Gln 
305                 310                 315                 320 


Arg Phe Gln Asp Gln Val Leu Asp Leu Leu Lys Thr Ser Val Val Lys 
                325                 330                 335     


Ser Phe Lys Asp Leu Gln Leu Leu Gln Gly Ser Lys Phe Leu Gln Asn 
            340                 345                 350         


Leu Val Pro His Arg Ser Tyr Val Ser Thr Met Ile Leu Glu Val Val 
        355                 360                 365             


Lys Asn Ser Val His Ser Trp Asp His Val Thr Gln Gly Leu Val Glu 
    370                 375                 380                 


Leu Gly Phe Ile Leu Met Asp Ser Tyr Gly Pro Lys Lys Val Leu Asp 
385                 390                 395                 400 


Gly Lys Thr Ile Glu Thr Ser Pro Ser Leu Ser Arg Met Pro Asn Gln 
                405                 410                 415     


His Ala Cys Lys Leu Gly Ala Asn Ile Leu Leu Glu Thr Phe Lys Ile 
            420                 425                 430         


His Glu Met Ile Arg Gln Glu Ile Leu Glu Gln Val Leu Asn Arg Val 
        435                 440                 445             


Val Thr Arg Ala Ser Ser Pro Ile Ser His Phe Leu Asp Leu Leu Ser 
    450                 455                 460                 


Asn Ile Val Met Tyr Ala Pro Leu Val Leu Gln Ser Cys Ser Ser Lys 
465                 470                 475                 480 


Val Thr Glu Ala Phe Asp Tyr Leu Ser Phe Leu Pro Leu Gln Thr Val 
                485                 490                 495     


Gln Arg Leu Leu Lys Ala Val Gln Pro Leu Leu Lys Val Ser Met Ser 
            500                 505                 510         


Met Arg Asp Cys Leu Ile Leu Val Leu Arg Lys Ala Met Phe Ala Asn 
        515                 520                 525             


Gln Leu Asp Ala Arg Lys Ser Ala Val Ala Gly Phe Leu Leu Leu Leu 
    530                 535                 540                 


Lys Asn Phe Lys Val Leu Gly Ser Leu Ser Ser Ser Gln Cys Ser Gln 
545                 550                 555                 560 


Ser Leu Ser Val Ser Gln Val His Val Asp Val His Ser His Tyr Asn 
                565                 570                 575     


Ser Val Ala Asn Glu Thr Phe Cys Leu Glu Ile Met Asp Ser Leu Arg 
            580                 585                 590         


Arg Cys Leu Ser Gln Gln Ala Asp Val Arg Leu Met Leu Tyr Glu Gly 
        595                 600                 605             


Phe Tyr Asp Val Leu Arg Arg Asn Ser Gln Leu Ala Asn Ser Val Met 
    610                 615                 620                 


Gln Thr Leu Leu Ser Gln Leu Lys Gln Phe Tyr Glu Pro Lys Pro Asp 
625                 630                 635                 640 


Leu Leu Pro Pro Leu Lys Leu Glu Ala Cys Ile Leu Thr Gln Gly Asp 
                645                 650                 655     


Lys Ile Ser Leu Gln Glu Pro Leu Asp Tyr Leu Leu Cys Cys Ile Gln 
            660                 665                 670         


His Cys Leu Ala Trp Tyr Lys Asn Thr Val Ile Pro Leu Gln Gln Gly 
        675                 680                 685             


Glu Glu Glu Glu Glu Glu Glu Glu Ala Phe Tyr Glu Asp Leu Asp Asp 
    690                 695                 700                 


Ile Leu Glu Ser Ile Thr Asn Arg Met Ile Lys Ser Glu Leu Glu Asp 
705                 710                 715                 720 


Phe Glu Leu Asp Lys Ser Ala Asp Phe Ser Gln Ser Thr Ser Ile Gly 
                725                 730                 735     


Ile Lys Asn Asn Ile Cys Ala Phe Leu Val Met Gly Val Cys Glu Val 
            740                 745                 750         


Leu Ile Glu Tyr Asn Phe Ser Ile Ser Ser Phe Ser Lys Asn Arg Phe 
        755                 760                 765             


Glu Asp Ile Leu Ser Leu Phe Met Cys Tyr Lys Lys Leu Ser Asp Ile 
    770                 775                 780                 


Leu Asn Glu Lys Ala Gly Lys Ala Lys Thr Lys Met Ala Asn Lys Thr 
785                 790                 795                 800 


Ser Asp Ser Leu Leu Ser Met Lys Phe Val Ser Ser Leu Leu Thr Ala 
                805                 810                 815     


Leu Phe Arg Asp Ser Ile Gln Ser His Gln Glu Ser Leu Ser Val Leu 
            820                 825                 830         


Arg Ser Ser Asn Glu Phe Met Arg Tyr Ala Val Asn Val Ala Leu Gln 
        835                 840                 845             


Lys Val Gln Gln Leu Lys Glu Thr Gly His Val Ser Gly Pro Asp Gly 
    850                 855                 860                 


Gln Asn Pro Glu Lys Ile Phe Gln Asn Leu Cys Asp Ile Thr Arg Val 
865                 870                 875                 880 


Leu Leu Trp Arg Tyr Thr Ser Ile Pro Thr Ser Val Glu Glu Ser Gly 
                885                 890                 895     


Lys Lys Glu Lys Gly Lys Ser Ile Ser Leu Leu Cys Leu Glu Gly Leu 
            900                 905                 910         


Gln Lys Ile Phe Ser Ala Val Gln Gln Phe Tyr Gln Pro Lys Ile Gln 
        915                 920                 925             


Gln Phe Leu Arg Ala Leu Asp Val Thr Asp Lys Glu Gly Glu Glu Arg 
    930                 935                 940                 


Glu Asp Ala Asp Val Ser Val Thr Gln Arg Thr Ala Phe Gln Ile Arg 
945                 950                 955                 960 


Gln Phe Gln Arg Ser Leu Leu Asn Leu Leu Ser Ser Gln Glu Glu Asp 
                965                 970                 975     


Phe Asn Ser Lys Glu Ala Leu Leu Leu Val Thr Val Leu Thr Ser Leu 
            980                 985                 990         


Ser Lys Leu Leu Glu Pro Ser Ser  Pro Gln Phe Val Gln  Met Leu Ser 
        995                 1000                 1005             


Trp Thr  Ser Lys Ile Cys Lys  Glu Asn Ser Arg Glu  Asp Ala Leu 
    1010                 1015                 1020             


Phe Cys  Lys Ser Leu Met Asn  Leu Leu Phe Ser Leu  His Val Ser 
    1025                 1030                 1035             


Tyr Lys  Ser Pro Val Ile Leu  Leu Arg Asp Leu Ser  Gln Asp Ile 
    1040                 1045                 1050             


His Gly  His Leu Gly Asp Ile  Asp Gln Asp Val Glu  Val Glu Lys 
    1055                 1060                 1065             


Thr Asn  His Phe Ala Ile Val  Asn Leu Arg Thr Ala  Ala Pro Thr 
    1070                 1075                 1080             


Val Cys  Leu Leu Val Leu Ser  Gln Ala Glu Lys Val  Leu Glu Glu 
    1085                 1090                 1095             


Val Asp  Trp Leu Ile Thr Lys  Leu Lys Gly Gln Val  Ser Gln Glu 
    1100                 1105                 1110             


Thr Leu  Ser Glu Glu Ala Ser  Ser Gln Ala Thr Leu  Pro Asn Gln 
    1115                 1120                 1125             


Pro Val  Glu Lys Ala Ile Ile  Met Gln Leu Gly Thr  Leu Leu Thr 
    1130                 1135                 1140             


Phe Phe  His Glu Leu Val Gln  Thr Ala Leu Pro Ser  Gly Ser Cys 
    1145                 1150                 1155             


Val Asp  Thr Leu Leu Lys Asp  Leu Cys Lys Met Tyr  Thr Thr Leu 
    1160                 1165                 1170             


Thr Ala  Leu Val Arg Tyr Tyr  Leu Gln Val Cys Gln  Ser Ser Gly 
    1175                 1180                 1185             


Gly Ile  Pro Lys Asn Met Glu  Lys Leu Val Lys Leu  Ser Gly Ser 
    1190                 1195                 1200             


His Leu  Thr Pro Leu Cys Tyr  Ser Phe Ile Ser Tyr  Val Gln Asn 
    1205                 1210                 1215             


Lys Ser  Lys Ser Leu Asn Tyr  Thr Gly Glu Lys Lys  Glu Lys Pro 
    1220                 1225                 1230             


Ala Ala  Val Ala Thr Ala Met  Ala Arg Val Leu Arg  Glu Thr Lys 
    1235                 1240                 1245             


Pro Ile  Pro Asn Leu Ile Phe  Ala Ile Glu Gln Tyr  Glu Lys Phe 
    1250                 1255                 1260             


Leu Ile  His Leu Ser Lys Lys  Ser Lys Val Asn Leu  Met Gln His 
    1265                 1270                 1275             


Met Lys  Leu Ser Thr Ser Arg  Asp Phe Lys Ile Lys  Gly Asn Ile 
    1280                 1285                 1290             


Leu Asp  Met Val Leu Arg Glu  Asp Gly Glu Asp Glu  Asn Glu Glu 
    1295                 1300                 1305             


Gly Thr  Ala Ser Glu His Gly  Gly Gln Asn Lys Glu  Pro Ala Lys 
    1310                 1315                 1320             


Lys Lys  Arg Lys Lys 
    1325             


<210>  3326
<211>  847
<212>  PRT
<213>  homo sapiens

<400>  3326

Met Lys Lys Thr Pro Val Phe Leu Glu Ser Leu Val Thr Asn Met Leu 
1               5                   10                  15      


Arg Leu Arg Ala Ile Cys Pro Phe Ser Trp Arg Val Phe Gln Phe Arg 
            20                  25                  30          


Pro Ile Ser Cys Glu Pro Leu Ile Ile Gln Met Asn Lys Cys Thr Asp 
        35                  40                  45              


Glu Glu Gln Met Phe Gly Phe Ile Glu Arg Asn Lys Ala Ile Leu Ser 
    50                  55                  60                  


Glu Lys Gln Val Gly Cys Ala Phe Asp Met Leu Trp Lys Leu Gln Lys 
65                  70                  75                  80  


Gln Lys Thr Ser Leu Leu Lys Asn Ala Glu Tyr Val Arg Asp His Pro 
                85                  90                  95      


Gln Phe Leu Thr Leu His Asn Leu Ala Thr Asn Lys Phe Lys Leu Met 
            100                 105                 110         


Asn Asp Asp Thr Leu Val Asn Val Leu Tyr Val Thr Gln Gln Phe Ala 
        115                 120                 125             


Gly Glu Ala His Asp Pro Leu Val Glu Ala Leu Val Thr Glu Ala Trp 
    130                 135                 140                 


Arg Arg Leu Glu Arg Phe Asp Ile Lys Leu Leu Ser Glu Phe Ser Ser 
145                 150                 155                 160 


Cys Leu Ala Asp Gln His Leu Tyr Phe Ser Pro Leu Met Gly Lys Ile 
                165                 170                 175     


Ala Asp Ile Val His Arg Asn Leu Glu Thr Thr Gln Asp Leu Ser Ser 
            180                 185                 190         


Leu Ser Val Leu Met Val Asn Ile Ser Ser Leu Ile Ser Arg His Phe 
        195                 200                 205             


Gln Gln Gln Leu Val Asn Lys Thr Glu Leu Leu Phe Asp Thr Ile Asp 
    210                 215                 220                 


Ser Ser Glu Val Asn Val Ala Lys Ser Ile Ala Lys Phe Leu Arg Asn 
225                 230                 235                 240 


Val Arg Tyr Arg Tyr Gln Pro Leu Leu Glu Arg Cys Asn Asn Val Phe 
                245                 250                 255     


Leu Ser Asn Val Asp His Leu Asp Leu Asp Ser Ile Ser Lys Ile Leu 
            260                 265                 270         


Ser Val Tyr Lys Phe Leu Gln Phe Asn Ser Phe Glu Phe Ile Ile Met 
        275                 280                 285             


Ala Lys Lys Lys Leu Thr Glu Met Ile Pro Leu Cys Asn His Pro Ala 
    290                 295                 300                 


Ser Phe Val Lys Leu Phe Val Ala Leu Gly Pro Ile Ala Gly Pro Glu 
305                 310                 315                 320 


Glu Lys Lys Gln Leu Lys Ser Thr Met Leu Leu Met Ser Glu Asp Leu 
                325                 330                 335     


Thr Gly Glu Gln Ala Leu Ala Val Leu Gly Ala Met Gly Asp Met Glu 
            340                 345                 350         


Ser Arg Asn Ser Cys Leu Ile Lys Arg Val Thr Ser Val Leu His Lys 
        355                 360                 365             


His Leu Asp Gly Tyr Lys Pro Leu Glu Leu Leu Lys Ile Thr Gln Glu 
    370                 375                 380                 


Leu Thr Phe Leu His Phe Gln Arg Lys Glu Phe Phe Ala Lys Leu Arg 
385                 390                 395                 400 


Glu Leu Leu Leu Ser Tyr Leu Lys Asn Ser Phe Ile Pro Thr Glu Val 
                405                 410                 415     


Ser Val Leu Val Arg Ala Ile Ser Leu Leu Pro Ser Pro His Leu Asp 
            420                 425                 430         


Glu Val Gly Ile Ser Arg Ile Glu Ala Val Leu Pro Gln Cys Asp Leu 
        435                 440                 445             


Asn Asn Leu Ser Ser Phe Ala Thr Ser Val Leu Arg Trp Ile Gln His 
    450                 455                 460                 


Asp His Met Tyr Leu Asp Asn Met Thr Ala Lys Gln Leu Lys Leu Leu 
465                 470                 475                 480 


Gln Lys Leu Asp His Tyr Gly Arg Gln Arg Leu Gln His Ser Asn Ser 
                485                 490                 495     


Leu Asp Leu Leu Arg Lys Glu Leu Lys Ser Leu Lys Gly Asn Thr Phe 
            500                 505                 510         


Pro Glu Ser Leu Leu Glu Glu Met Ile Ala Thr Leu Gln His Phe Met 
        515                 520                 525             


Asp Asp Ile Asn Tyr Ile Asn Val Gly Glu Ile Ala Ser Phe Ile Ser 
    530                 535                 540                 


Ser Thr Asp Tyr Leu Ser Thr Leu Leu Leu Asp Arg Ile Ala Ser Val 
545                 550                 555                 560 


Ala Val Gln Gln Ile Glu Lys Ile His Pro Phe Thr Ile Pro Ala Ile 
                565                 570                 575     


Ile Arg Pro Phe Ser Val Leu Asn Tyr Asp Pro Pro Gln Arg Asp Glu 
            580                 585                 590         


Phe Leu Gly Thr Cys Val Gln His Leu Asn Ser Tyr Leu Gly Ile Leu 
        595                 600                 605             


Asp Pro Phe Ile Leu Val Phe Leu Gly Phe Ser Leu Ala Thr Leu Glu 
    610                 615                 620                 


Tyr Phe Pro Glu Asp Leu Leu Lys Ala Ile Phe Asn Ile Lys Phe Leu 
625                 630                 635                 640 


Ala Arg Leu Asp Ser Gln Leu Glu Ile Leu Ser Pro Ser Arg Ser Ala 
                645                 650                 655     


Arg Val Gln Phe His Leu Met Glu Leu Asn Arg Ser Val Cys Leu Glu 
            660                 665                 670         


Cys Pro Glu Phe Gln Ile Pro Trp Phe His Asp Arg Phe Cys Gln Gln 
        675                 680                 685             


Tyr Asn Lys Gly Ile Gly Gly Met Asp Gly Thr Gln Gln Gln Ile Phe 
    690                 695                 700                 


Lys Met Leu Ala Glu Val Leu Gly Gly Ile Asn Cys Val Lys Ala Ser 
705                 710                 715                 720 


Val Leu Thr Pro Tyr Tyr His Lys Val Asp Phe Glu Cys Ile Leu Asp 
                725                 730                 735     


Lys Arg Lys Lys Pro Leu Pro Tyr Gly Ser His Asn Ile Ala Leu Gly 
            740                 745                 750         


Gln Leu Pro Glu Met Pro Trp Glu Ser Asn Ile Glu Ile Val Gly Ser 
        755                 760                 765             


Arg Leu Pro Pro Gly Ala Glu Arg Ile Ala Leu Glu Phe Leu Asp Ser 
    770                 775                 780                 


Lys Ala Leu Cys Arg Asn Ile Pro His Met Lys Gly Lys Ser Ala Met 
785                 790                 795                 800 


Lys Lys Arg His Leu Glu Ile Leu Gly Tyr Arg Val Ile Gln Ile Ser 
                805                 810                 815     


Gln Phe Glu Trp Asn Ser Met Ala Leu Ser Thr Lys Asp Ala Arg Met 
            820                 825                 830         


Asp Tyr Leu Arg Glu Cys Ile Phe Gly Glu Val Lys Ser Cys Leu 
        835                 840                 845         


<210>  3327
<211>  459
<212>  PRT
<213>  homo sapiens

<400>  3327

Met Ala Ser Ser Ala Ser Leu Glu Thr Met Val Pro Pro Ala Cys Pro 
1               5                   10                  15      


Arg Ala Gly Ala Ser Pro Ala Thr Ser Lys Thr Leu Ala Phe Ser Ile 
            20                  25                  30          


Glu Arg Ile Met Ala Lys Thr Ser Glu Pro Arg Ala Pro Phe Glu Pro 
        35                  40                  45              


Arg Pro Gly Ala Leu Glu Ala Asp Gly Ser Gln Gly Lys Lys Leu Leu 
    50                  55                  60                  


Asn Leu Cys Ser Pro Leu Pro Cys Met Ile Pro Leu Gln Pro Leu Gly 
65                  70                  75                  80  


Tyr Glu Val Pro Ser Lys Thr Leu Leu Ser Tyr Ser Glu Leu Trp Lys 
                85                  90                  95      


Ser Ser Leu Arg Ala Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly 
            100                 105                 110         


Gly Gly Gly Gly Gly Ala Pro Val Cys Gly Ala Ser Gly Leu Cys Lys 
        115                 120                 125             


Thr Asn Cys Gly Val Cys Cys Lys Ala Glu Leu Gly Leu Ala Pro Ser 
    130                 135                 140                 


Ala Leu Pro Ala Gly Arg Val Ile Lys Pro Gln Val Ile Asn Gln Ala 
145                 150                 155                 160 


Val Gly Leu Pro Ala Ser Gly Ser Leu Tyr Tyr Phe Asn Tyr Leu Asp 
                165                 170                 175     


Ser Thr Ala Tyr Pro Pro Ser Glu Leu Leu Ser Gly His Leu Phe Pro 
            180                 185                 190         


Ser Gly Leu Leu Asn Ala Gln Ala Pro Ala Ala Leu Ala Ala His Pro 
        195                 200                 205             


Lys Leu Phe Leu Leu Glu Asn Ala Lys Leu Ala Gly Leu Ala Ala Asp 
    210                 215                 220                 


Lys Phe Pro His Pro Ala Pro Tyr Pro His Lys Glu Arg Leu Pro Ala 
225                 230                 235                 240 


Pro Leu Glu Gln Val Leu Lys Glu Asn Ser Ala Leu Thr Ala Glu Arg 
                245                 250                 255     


Gly Gly Val Lys Gly His Ser Lys Leu Pro Gly Gly Ser Ala Asp Gly 
            260                 265                 270         


Lys Pro Lys Asn Phe Thr Cys Glu Val Cys Gly Lys Val Phe Asn Ala 
        275                 280                 285             


His Tyr Asn Leu Thr Arg His Met Pro Val His Thr Gly Ala Arg Pro 
    290                 295                 300                 


Phe Val Cys Lys Val Cys Gly Lys Gly Phe Arg Gln Ala Ser Thr Leu 
305                 310                 315                 320 


Cys Arg His Lys Ile Ile His Thr Gln Glu Lys Pro His Lys Cys Asn 
                325                 330                 335     


Gln Cys Gly Lys Ala Phe Asn Arg Ser Ser Thr Leu Asn Thr His Ile 
            340                 345                 350         


Arg Ile His Ala Gly Tyr Lys Pro Phe Val Cys Glu Phe Cys Gly Lys 
        355                 360                 365             


Gly Phe His Gln Lys Gly Asn Tyr Lys Asn His Lys Leu Thr His Ser 
    370                 375                 380                 


Gly Glu Lys Gln Tyr Lys Cys Thr Ile Cys Asn Lys Ala Phe His Gln 
385                 390                 395                 400 


Val Tyr Asn Leu Thr Phe His Met His Thr His Asn Asp Lys Lys Pro 
                405                 410                 415     


Phe Thr Cys Ala Thr Cys Gly Lys Gly Phe Cys Arg Asn Phe Asp Leu 
            420                 425                 430         


Lys Lys His Val Arg Lys Leu His Asp Ser Val Gly Pro Ala Ala Pro 
        435                 440                 445             


Ser Ala Lys Asp Leu Thr Arg Thr Val Gln Ser 
    450                 455                 


<210>  3328
<211>  486
<212>  PRT
<213>  homo sapiens

<400>  3328

Met Lys Gly Arg Arg Arg Arg Arg Arg Glu Tyr Cys Lys Phe Ala Leu 
1               5                   10                  15      


Leu Leu Val Leu Tyr Thr Leu Val Leu Leu Leu Val Pro Ser Val Leu 
            20                  25                  30          


Asp Gly Gly Arg Asp Gly Asp Lys Gly Ala Glu His Cys Pro Gly Leu 
        35                  40                  45              


Gln Arg Ser Leu Gly Val Trp Ser Leu Glu Ala Ala Ala Ala Gly Glu 
    50                  55                  60                  


Arg Glu Gln Gly Ala Glu Ala Arg Ala Ala Glu Glu Gly Gly Ala Asn 
65                  70                  75                  80  


Gln Ser Pro Arg Phe Pro Ser Asn Leu Ser Gly Ala Val Gly Glu Ala 
                85                  90                  95      


Val Ser Arg Glu Lys Gln His Ile Tyr Val His Ala Thr Trp Arg Thr 
            100                 105                 110         


Gly Ser Ser Phe Leu Gly Glu Leu Phe Asn Gln His Pro Asp Val Phe 
        115                 120                 125             


Tyr Leu Tyr Glu Pro Met Trp His Leu Trp Gln Ala Leu Tyr Pro Gly 
    130                 135                 140                 


Asp Ala Glu Ser Leu Gln Gly Ala Leu Arg Asp Met Leu Arg Ser Leu 
145                 150                 155                 160 


Phe Arg Cys Asp Phe Ser Val Leu Arg Leu Tyr Ala Pro Pro Gly Asp 
                165                 170                 175     


Pro Ala Ala Arg Ala Pro Asp Thr Ala Asn Leu Thr Thr Ala Ala Leu 
            180                 185                 190         


Phe Arg Trp Arg Thr Asn Lys Val Ile Cys Ser Pro Pro Leu Cys Pro 
        195                 200                 205             


Gly Ala Pro Arg Ala Arg Ala Glu Val Gly Leu Val Glu Asp Thr Ala 
    210                 215                 220                 


Cys Glu Arg Ser Cys Pro Pro Val Ala Ile Arg Ala Leu Glu Ala Glu 
225                 230                 235                 240 


Cys Arg Lys Tyr Pro Val Val Val Ile Lys Asp Val Arg Leu Leu Asp 
                245                 250                 255     


Leu Gly Val Leu Val Pro Leu Leu Arg Asp Pro Gly Leu Asn Leu Lys 
            260                 265                 270         


Val Val Gln Leu Phe Arg Asp Pro Arg Ala Val His Asn Ser Arg Leu 
        275                 280                 285             


Lys Ser Arg Gln Gly Leu Leu Arg Glu Ser Ile Gln Val Leu Arg Thr 
    290                 295                 300                 


Arg Gln Arg Gly Asp Arg Phe His Arg Val Leu Leu Ala His Gly Val 
305                 310                 315                 320 


Gly Ala Arg Pro Gly Gly Gln Ser Arg Ala Leu Pro Ala Ala Pro Arg 
                325                 330                 335     


Ala Asp Phe Phe Leu Thr Gly Ala Leu Glu Val Ile Cys Glu Ala Trp 
            340                 345                 350         


Leu Arg Asp Leu Leu Phe Ala Arg Gly Ala Pro Ala Trp Leu Arg Arg 
        355                 360                 365             


Arg Tyr Leu Arg Leu Arg Tyr Glu Asp Leu Val Arg Gln Pro Arg Ala 
    370                 375                 380                 


Gln Leu Arg Arg Leu Leu Arg Phe Ser Gly Leu Arg Ala Leu Ala Ala 
385                 390                 395                 400 


Leu Asp Ala Phe Ala Leu Asn Met Thr Arg Gly Ala Ala Tyr Gly Ala 
                405                 410                 415     


Asp Arg Pro Phe His Leu Ser Ala Arg Asp Ala Arg Glu Ala Val His 
            420                 425                 430         


Ala Trp Arg Glu Arg Leu Ser Arg Glu Gln Val Arg Gln Val Glu Ala 
        435                 440                 445             


Ala Cys Ala Pro Ala Met Arg Leu Leu Ala Tyr Pro Arg Ser Gly Glu 
    450                 455                 460                 


Glu Gly Asp Ala Glu Gln Pro Arg Glu Gly Glu Thr Pro Leu Glu Met 
465                 470                 475                 480 


Asp Ala Asp Gly Ala Thr 
                485     


<210>  3329
<211>  439
<212>  PRT
<213>  homo sapiens

<400>  3329

Met Pro Ala Ile Ala Val Leu Ala Ala Ala Ala Ala Ala Trp Cys Phe 
1               5                   10                  15      


Leu Gln Val Glu Ser Arg His Leu Asp Ala Leu Ala Gly Gly Ala Gly 
            20                  25                  30          


Pro Asn His Gly Asn Phe Leu Asp Asn Asp Gln Trp Leu Ser Thr Val 
        35                  40                  45              


Ser Gln Tyr Asp Arg Asp Lys Tyr Trp Asn Arg Phe Arg Asp Asp Asp 
    50                  55                  60                  


Tyr Phe Arg Asn Trp Asn Pro Asn Lys Pro Phe Asp Gln Ala Leu Asp 
65                  70                  75                  80  


Pro Ser Lys Asp Pro Cys Leu Lys Val Lys Cys Ser Pro His Lys Val 
                85                  90                  95      


Cys Val Thr Gln Asp Tyr Gln Thr Ala Leu Cys Val Ser Arg Lys His 
            100                 105                 110         


Leu Leu Pro Arg Gln Lys Lys Gly Asn Val Ala Gln Lys His Trp Val 
        115                 120                 125             


Gly Pro Ser Asn Leu Val Lys Cys Lys Pro Cys Pro Val Ala Gln Ser 
    130                 135                 140                 


Ala Met Val Cys Gly Ser Asp Gly His Ser Tyr Thr Ser Lys Cys Lys 
145                 150                 155                 160 


Leu Glu Phe His Ala Cys Ser Thr Gly Lys Ser Leu Ala Thr Leu Cys 
                165                 170                 175     


Asp Gly Pro Cys Pro Cys Leu Pro Glu Pro Glu Pro Pro Lys His Lys 
            180                 185                 190         


Ala Glu Arg Ser Ala Cys Thr Asp Lys Glu Leu Arg Asn Leu Ala Ser 
        195                 200                 205             


Arg Leu Lys Asp Trp Phe Gly Ala Leu His Glu Asp Ala Asn Arg Val 
    210                 215                 220                 


Ile Lys Pro Thr Ser Ser Asn Thr Ala Gln Gly Arg Phe Asp Thr Ser 
225                 230                 235                 240 


Ile Leu Pro Ile Cys Lys Asp Ser Leu Gly Trp Met Phe Asn Lys Leu 
                245                 250                 255     


Asp Met Asn Tyr Asp Leu Leu Leu Asp Pro Ser Glu Ile Asn Ala Ile 
            260                 265                 270         


Tyr Leu Asp Lys Tyr Glu Pro Cys Ile Lys Pro Leu Phe Asn Ser Cys 
        275                 280                 285             


Asp Ser Phe Lys Asp Gly Lys Leu Ser Asn Asn Glu Trp Cys Tyr Cys 
    290                 295                 300                 


Phe Gln Lys Pro Gly Gly Leu Pro Cys Gln Asn Glu Met Asn Arg Ile 
305                 310                 315                 320 


Gln Lys Leu Ser Lys Gly Lys Ser Leu Leu Gly Ala Phe Ile Pro Arg 
                325                 330                 335     


Cys Asn Glu Glu Gly Tyr Tyr Lys Ala Thr Gln Cys His Gly Ser Thr 
            340                 345                 350         


Gly Gln Cys Trp Cys Val Asp Lys Tyr Gly Asn Glu Leu Ala Gly Ser 
        355                 360                 365             


Arg Lys Gln Gly Ala Val Ser Cys Glu Glu Glu Gln Glu Thr Ser Gly 
    370                 375                 380                 


Asp Phe Gly Ser Gly Gly Ser Val Val Leu Leu Asp Asp Leu Glu Tyr 
385                 390                 395                 400 


Glu Arg Glu Leu Gly Pro Lys Asp Lys Glu Gly Lys Leu Arg Val His 
                405                 410                 415     


Thr Arg Ala Val Thr Glu Asp Asp Glu Asp Glu Asp Asp Asp Lys Glu 
            420                 425                 430         


Asp Glu Val Gly Tyr Ile Trp 
        435                 


<210>  3330
<211>  1097
<212>  PRT
<213>  homo sapiens

<400>  3330

Met Ala Thr Gln Val Met Gly Gln Ser Ser Gly Gly Gly Gly Leu Phe 
1               5                   10                  15      


Thr Ser Ser Gly Asn Ile Gly Met Ala Leu Pro Asn Asp Met Tyr Asp 
            20                  25                  30          


Leu His Asp Leu Ser Lys Ala Glu Leu Ala Ala Pro Gln Leu Ile Met 
        35                  40                  45              


Leu Ala Asn Val Ala Leu Thr Gly Glu Val Asn Gly Ser Cys Cys Asp 
    50                  55                  60                  


Tyr Leu Val Gly Glu Glu Arg Gln Met Ala Glu Leu Met Pro Val Gly 
65                  70                  75                  80  


Asp Asn Asn Phe Ser Asp Ser Glu Glu Gly Glu Gly Leu Glu Glu Ser 
                85                  90                  95      


Ala Asp Ile Lys Gly Glu Pro His Gly Leu Glu Asn Met Glu Leu Arg 
            100                 105                 110         


Ser Leu Glu Leu Ser Val Val Glu Pro Gln Pro Val Phe Glu Ala Ser 
        115                 120                 125             


Gly Ala Pro Asp Ile Tyr Ser Ser Asn Lys Asp Leu Pro Pro Glu Thr 
    130                 135                 140                 


Pro Gly Ala Glu Asp Lys Gly Lys Ser Ser Lys Thr Lys Pro Phe Arg 
145                 150                 155                 160 


Cys Lys Pro Cys Gln Tyr Glu Ala Glu Ser Glu Glu Gln Phe Val His 
                165                 170                 175     


His Ile Arg Val His Ser Ala Lys Lys Phe Phe Val Glu Glu Ser Ala 
            180                 185                 190         


Glu Lys Gln Ala Lys Ala Arg Glu Ser Gly Ser Ser Thr Ala Glu Glu 
        195                 200                 205             


Gly Asp Phe Ser Lys Gly Pro Ile Arg Cys Asp Arg Cys Gly Tyr Asn 
    210                 215                 220                 


Thr Asn Arg Tyr Asp His Tyr Thr Ala His Leu Lys His His Thr Arg 
225                 230                 235                 240 


Ala Gly Asp Asn Glu Arg Val Tyr Lys Cys Ile Ile Cys Thr Tyr Thr 
                245                 250                 255     


Thr Val Ser Glu Tyr His Trp Arg Lys His Leu Arg Asn His Phe Pro 
            260                 265                 270         


Arg Lys Val Tyr Thr Cys Gly Lys Cys Asn Tyr Phe Ser Asp Arg Lys 
        275                 280                 285             


Asn Asn Tyr Val Gln His Val Arg Thr His Thr Gly Glu Arg Pro Tyr 
    290                 295                 300                 


Lys Cys Glu Leu Cys Pro Tyr Ser Ser Ser Gln Lys Thr His Leu Thr 
305                 310                 315                 320 


Arg His Met Arg Thr His Ser Gly Glu Lys Pro Phe Lys Cys Asp Gln 
                325                 330                 335     


Cys Ser Tyr Val Ala Ser Asn Gln His Glu Val Thr Arg His Ala Arg 
            340                 345                 350         


Gln Val His Asn Gly Pro Lys Pro Leu Asn Cys Pro His Cys Asp Tyr 
        355                 360                 365             


Lys Thr Ala Asp Arg Ser Asn Phe Lys Lys His Val Glu Leu His Val 
    370                 375                 380                 


Asn Pro Arg Gln Phe Asn Cys Pro Val Cys Asp Tyr Ala Ala Ser Lys 
385                 390                 395                 400 


Lys Cys Asn Leu Gln Tyr His Phe Lys Ser Lys His Pro Thr Cys Pro 
                405                 410                 415     


Asn Lys Thr Met Asp Val Ser Lys Val Lys Leu Lys Lys Thr Lys Lys 
            420                 425                 430         


Arg Glu Ala Asp Leu Pro Asp Asn Ile Thr Asn Glu Lys Thr Glu Ile 
        435                 440                 445             


Glu Gln Thr Lys Ile Lys Gly Asp Val Ala Gly Lys Lys Asn Glu Lys 
    450                 455                 460                 


Ser Val Lys Ala Glu Lys Arg Asp Val Ser Lys Glu Lys Lys Pro Ser 
465                 470                 475                 480 


Asn Asn Val Ser Val Ile Gln Val Thr Thr Arg Thr Arg Lys Ser Val 
                485                 490                 495     


Thr Glu Val Lys Glu Met Asp Val His Thr Gly Ser Asn Ser Glu Lys 
            500                 505                 510         


Phe Ser Lys Thr Lys Lys Ser Lys Arg Lys Leu Glu Val Asp Ser His 
        515                 520                 525             


Ser Leu His Gly Pro Val Asn Asp Glu Glu Ser Ser Thr Lys Lys Lys 
    530                 535                 540                 


Lys Lys Val Glu Ser Lys Ser Lys Asn Asn Ser Gln Glu Val Pro Lys 
545                 550                 555                 560 


Gly Asp Ser Lys Val Glu Glu Asn Lys Lys Gln Asn Thr Cys Met Lys 
                565                 570                 575     


Lys Ser Thr Lys Lys Lys Thr Leu Lys Asn Lys Ser Ser Lys Lys Ser 
            580                 585                 590         


Ser Lys Pro Pro Gln Lys Glu Pro Val Glu Lys Gly Ser Ala Gln Met 
        595                 600                 605             


Asp Pro Pro Gln Met Gly Pro Ala Pro Thr Glu Ala Val Gln Lys Gly 
    610                 615                 620                 


Pro Val Gln Val Glu Pro Pro Pro Pro Met Glu His Ala Gln Met Glu 
625                 630                 635                 640 


Gly Ala Gln Ile Arg Pro Ala Pro Asp Glu Pro Val Gln Met Glu Val 
                645                 650                 655     


Val Gln Glu Gly Pro Ala Gln Lys Glu Leu Leu Pro Pro Val Glu Pro 
            660                 665                 670         


Ala Gln Met Val Gly Ala Gln Ile Val Leu Ala His Met Glu Leu Pro 
        675                 680                 685             


Pro Pro Met Glu Thr Ala Gln Thr Glu Val Ala Gln Met Gly Pro Ala 
    690                 695                 700                 


Pro Met Glu Pro Ala Gln Met Glu Val Ala Gln Val Glu Ser Ala Pro 
705                 710                 715                 720 


Met Gln Val Val Gln Lys Glu Pro Val Gln Met Glu Leu Ser Pro Pro 
                725                 730                 735     


Met Glu Val Val Gln Lys Glu Pro Val Gln Ile Glu Leu Ser Pro Pro 
            740                 745                 750         


Met Glu Val Val Gln Lys Glu Pro Val Lys Ile Glu Leu Ser Pro Pro 
        755                 760                 765             


Ile Glu Val Val Gln Lys Glu Pro Val Gln Met Glu Leu Ser Pro Pro 
    770                 775                 780                 


Met Gly Val Val Gln Lys Glu Pro Ala Gln Arg Glu Pro Pro Pro Pro 
785                 790                 795                 800 


Arg Glu Pro Pro Leu His Met Glu Pro Ile Ser Lys Lys Pro Pro Leu 
                805                 810                 815     


Arg Lys Asp Lys Lys Glu Lys Ser Asn Met Gln Ser Glu Arg Ala Arg 
            820                 825                 830         


Lys Glu Gln Val Leu Ile Glu Val Gly Leu Val Pro Val Lys Asp Ser 
        835                 840                 845             


Trp Leu Leu Lys Glu Ser Val Ser Thr Glu Asp Leu Ser Pro Pro Ser 
    850                 855                 860                 


Pro Pro Leu Pro Lys Glu Asn Leu Arg Glu Glu Ala Ser Gly Asp Gln 
865                 870                 875                 880 


Lys Leu Leu Asn Thr Gly Glu Gly Asn Lys Glu Ala Pro Leu Gln Lys 
                885                 890                 895     


Val Gly Ala Glu Glu Ala Asp Glu Ser Leu Pro Gly Leu Ala Ala Asn 
            900                 905                 910         


Ile Asn Glu Ser Thr His Ile Ser Ser Ser Gly Gln Asn Leu Asn Thr 
        915                 920                 925             


Pro Glu Gly Glu Thr Leu Asn Gly Lys His Gln Thr Asp Ser Ile Val 
    930                 935                 940                 


Cys Glu Met Lys Met Asp Thr Asp Gln Asn Thr Arg Glu Asn Leu Thr 
945                 950                 955                 960 


Gly Ile Asn Ser Thr Val Glu Glu Pro Val Ser Pro Met Leu Pro Pro 
                965                 970                 975     


Ser Ala Val Glu Glu Arg Glu Ala Val Ser Lys Thr Ala Leu Ala Ser 
            980                 985                 990         


Pro Pro Ala Thr Met Ala Ala Asn  Glu Ser Gln Glu Ile  Asp Glu Asp 
        995                 1000                 1005             


Glu Gly  Ile His Ser His Glu  Gly Ser Asp Leu Ser  Asp Asn Met 
    1010                 1015                 1020             


Ser Glu  Gly Ser Asp Asp Ser  Gly Leu His Gly Ala  Arg Pro Val 
    1025                 1030                 1035             


Pro Gln  Glu Ser Ser Arg Lys  Asn Ala Lys Glu Ala  Leu Ala Val 
    1040                 1045                 1050             


Lys Ala  Ala Lys Gly Asp Phe  Val Cys Ile Phe Cys  Asp Arg Ser 
    1055                 1060                 1065             


Phe Arg  Lys Gly Lys Asp Tyr  Ser Lys His Leu Asn  Arg His Leu 
    1070                 1075                 1080             


Val Asn  Val Tyr Tyr Leu Glu  Glu Ala Ala Gln Gly  Gln Glu 
    1085                 1090                 1095         


<210>  3331
<211>  906
<212>  PRT
<213>  homo sapiens

<400>  3331

Met Ala Gly Asn Val Lys Lys Ser Ser Gly Ala Gly Gly Gly Ser Gly 
1               5                   10                  15      


Ser Gly Gly Ser Gly Ser Gly Gly Leu Ile Gly Leu Met Lys Asp Ala 
            20                  25                  30          


Phe Gln Pro His His His His His His His Leu Ser Pro His Pro Pro 
        35                  40                  45              


Gly Thr Val Asp Lys Lys Met Val Glu Lys Cys Trp Lys Leu Met Asp 
    50                  55                  60                  


Lys Val Val Arg Leu Cys Gln Asn Pro Lys Leu Ala Leu Lys Asn Ser 
65                  70                  75                  80  


Pro Pro Tyr Ile Leu Asp Leu Leu Pro Asp Thr Tyr Gln His Leu Arg 
                85                  90                  95      


Thr Ile Leu Ser Arg Tyr Glu Gly Lys Met Glu Thr Leu Gly Glu Asn 
            100                 105                 110         


Glu Tyr Phe Arg Val Phe Met Glu Asn Leu Met Lys Lys Thr Lys Gln 
        115                 120                 125             


Thr Ile Ser Leu Phe Lys Glu Gly Lys Glu Arg Met Tyr Glu Glu Asn 
    130                 135                 140                 


Ser Gln Pro Arg Arg Asn Leu Thr Lys Leu Ser Leu Ile Phe Ser His 
145                 150                 155                 160 


Met Leu Ala Glu Leu Lys Gly Ile Phe Pro Ser Gly Leu Phe Gln Gly 
                165                 170                 175     


Asp Thr Phe Arg Ile Thr Lys Ala Asp Ala Ala Glu Phe Trp Arg Lys 
            180                 185                 190         


Ala Phe Gly Glu Lys Thr Ile Val Pro Trp Lys Ser Phe Arg Gln Ala 
        195                 200                 205             


Leu His Glu Val His Pro Ile Ser Ser Gly Leu Glu Ala Met Ala Leu 
    210                 215                 220                 


Lys Ser Thr Ile Asp Leu Thr Cys Asn Asp Tyr Ile Ser Val Phe Glu 
225                 230                 235                 240 


Phe Asp Ile Phe Thr Arg Leu Phe Gln Pro Trp Ser Ser Leu Leu Arg 
                245                 250                 255     


Asn Trp Asn Ser Leu Ala Val Thr His Pro Gly Tyr Met Ala Phe Leu 
            260                 265                 270         


Thr Tyr Asp Glu Val Lys Ala Arg Leu Gln Lys Phe Ile His Lys Pro 
        275                 280                 285             


Gly Ser Tyr Ile Phe Arg Leu Ser Cys Thr Arg Leu Gly Gln Trp Ala 
    290                 295                 300                 


Ile Gly Tyr Val Thr Ala Asp Gly Asn Ile Leu Gln Thr Ile Pro His 
305                 310                 315                 320 


Asn Lys Pro Leu Phe Gln Ala Leu Ile Asp Gly Phe Arg Glu Gly Phe 
                325                 330                 335     


Tyr Leu Phe Pro Asp Gly Arg Asn Gln Asn Pro Asp Leu Thr Gly Leu 
            340                 345                 350         


Cys Glu Pro Thr Pro Gln Asp His Ile Lys Val Thr Gln Glu Gln Tyr 
        355                 360                 365             


Glu Leu Tyr Cys Glu Met Gly Ser Thr Phe Gln Leu Cys Lys Ile Cys 
    370                 375                 380                 


Ala Glu Asn Asp Lys Asp Val Lys Ile Glu Pro Cys Gly His Leu Met 
385                 390                 395                 400 


Cys Thr Ser Cys Leu Thr Ser Trp Gln Glu Ser Glu Gly Gln Gly Cys 
                405                 410                 415     


Pro Phe Cys Arg Cys Glu Ile Lys Gly Thr Glu Pro Ile Val Val Asp 
            420                 425                 430         


Pro Phe Asp Pro Arg Gly Ser Gly Ser Leu Leu Arg Gln Gly Ala Glu 
        435                 440                 445             


Gly Ala Pro Ser Pro Asn Tyr Asp Asp Asp Asp Asp Glu Arg Ala Asp 
    450                 455                 460                 


Asp Thr Leu Phe Met Met Lys Glu Leu Ala Gly Ala Lys Val Glu Arg 
465                 470                 475                 480 


Pro Pro Ser Pro Phe Ser Met Ala Pro Gln Ala Ser Leu Pro Pro Val 
                485                 490                 495     


Pro Pro Arg Leu Asp Leu Leu Pro Gln Arg Val Cys Val Pro Ser Ser 
            500                 505                 510         


Ala Ser Ala Leu Gly Thr Ala Ser Lys Ala Ala Ser Gly Ser Leu His 
        515                 520                 525             


Lys Asp Lys Pro Leu Pro Val Pro Pro Thr Leu Arg Asp Leu Pro Pro 
    530                 535                 540                 


Pro Pro Pro Pro Asp Arg Pro Tyr Ser Val Gly Ala Glu Ser Arg Pro 
545                 550                 555                 560 


Gln Arg Arg Pro Leu Pro Cys Thr Pro Gly Asp Cys Pro Ser Arg Asp 
                565                 570                 575     


Lys Leu Pro Pro Val Pro Ser Ser Arg Leu Gly Asp Ser Trp Leu Pro 
            580                 585                 590         


Arg Pro Ile Pro Lys Val Pro Val Ser Ala Pro Ser Ser Ser Asp Pro 
        595                 600                 605             


Trp Thr Gly Arg Glu Leu Thr Asn Arg His Ser Leu Pro Phe Ser Leu 
    610                 615                 620                 


Pro Ser Gln Met Glu Pro Arg Pro Asp Val Pro Arg Leu Gly Ser Thr 
625                 630                 635                 640 


Phe Ser Leu Asp Thr Ser Met Ser Met Asn Ser Ser Pro Leu Val Gly 
                645                 650                 655     


Pro Glu Cys Asp His Pro Lys Ile Lys Pro Ser Ser Ser Ala Asn Ala 
            660                 665                 670         


Ile Tyr Ser Leu Ala Ala Arg Pro Leu Pro Val Pro Lys Leu Pro Pro 
        675                 680                 685             


Gly Glu Gln Cys Glu Gly Glu Glu Asp Thr Glu Tyr Met Thr Pro Ser 
    690                 695                 700                 


Ser Arg Pro Leu Arg Pro Leu Asp Thr Ser Gln Ser Ser Arg Ala Cys 
705                 710                 715                 720 


Asp Cys Asp Gln Gln Ile Asp Ser Cys Thr Tyr Glu Ala Met Tyr Asn 
                725                 730                 735     


Ile Gln Ser Gln Ala Pro Ser Ile Thr Glu Ser Ser Thr Phe Gly Glu 
            740                 745                 750         


Gly Asn Leu Ala Ala Ala His Ala Asn Thr Gly Pro Glu Glu Ser Glu 
        755                 760                 765             


Asn Glu Asp Asp Gly Tyr Asp Val Pro Lys Pro Pro Val Pro Ala Val 
    770                 775                 780                 


Leu Ala Arg Arg Thr Leu Ser Asp Ile Ser Asn Ala Ser Ser Ser Phe 
785                 790                 795                 800 


Gly Trp Leu Ser Leu Asp Gly Asp Pro Thr Thr Asn Val Thr Glu Gly 
                805                 810                 815     


Ser Gln Val Pro Glu Arg Pro Pro Lys Pro Phe Pro Arg Arg Ile Asn 
            820                 825                 830         


Ser Glu Arg Lys Ala Gly Ser Cys Gln Gln Gly Ser Gly Pro Ala Ala 
        835                 840                 845             


Ser Ala Ala Thr Ala Ser Pro Gln Leu Ser Ser Glu Ile Glu Asn Leu 
    850                 855                 860                 


Met Ser Gln Gly Tyr Ser Tyr Gln Asp Ile Gln Lys Ala Leu Val Ile 
865                 870                 875                 880 


Ala Gln Asn Asn Ile Glu Met Ala Lys Asn Ile Leu Arg Glu Phe Val 
                885                 890                 895     


Ser Ile Ser Ser Pro Ala His Val Ala Thr 
            900                 905     


<210>  3332
<211>  229
<212>  PRT
<213>  homo sapiens

<400>  3332

Met Gly Asp Pro Asn Ser Arg Lys Lys Gln Ala Leu Asn Arg Leu Arg 
1               5                   10                  15      


Ala Gln Leu Arg Lys Lys Lys Glu Ser Leu Ala Asp Gln Phe Asp Phe 
            20                  25                  30          


Lys Met Tyr Ile Ala Phe Val Phe Lys Glu Lys Lys Lys Lys Ser Ala 
        35                  40                  45              


Leu Phe Glu Val Ser Glu Val Ile Pro Val Met Thr Asn Asn Tyr Glu 
    50                  55                  60                  


Glu Asn Ile Leu Lys Gly Val Arg Asp Ser Ser Tyr Ser Leu Glu Ser 
65                  70                  75                  80  


Ser Leu Glu Leu Leu Gln Lys Asp Val Val Gln Leu His Ala Pro Arg 
                85                  90                  95      


Tyr Gln Ser Met Arg Arg Asp Val Ile Gly Cys Thr Gln Glu Met Asp 
            100                 105                 110         


Phe Ile Leu Trp Pro Arg Asn Asp Ile Glu Lys Ile Val Cys Leu Leu 
        115                 120                 125             


Phe Ser Arg Trp Lys Glu Ser Asp Glu Pro Phe Arg Pro Val Gln Ala 
    130                 135                 140                 


Lys Phe Glu Phe His His Gly Asp Tyr Glu Lys Gln Phe Leu His Val 
145                 150                 155                 160 


Leu Ser Arg Lys Asp Lys Thr Gly Ile Val Val Asn Asn Pro Asn Gln 
                165                 170                 175     


Ser Val Phe Leu Phe Ile Asp Arg Gln His Leu Gln Thr Pro Lys Asn 
            180                 185                 190         


Lys Ala Thr Ile Phe Lys Leu Cys Ser Ile Cys Leu Tyr Leu Pro Gln 
        195                 200                 205             


Glu Gln Leu Thr His Trp Ala Val Gly Thr Ile Glu Asp His Leu Arg 
    210                 215                 220                 


Pro Tyr Met Pro Glu 
225                 


<210>  3333
<211>  79
<212>  PRT
<213>  homo sapiens

<400>  3333

Met Ala Arg Ser Arg Leu Thr Ala Thr Ser Val Ser Gln Val Gln Glu 
1               5                   10                  15      


Asn Gly Phe Val Lys Lys Leu Glu Pro Lys Ser Gly Trp Met Thr Phe 
            20                  25                  30          


Leu Glu Val Thr Gly Lys Ile Cys Glu Met Leu Phe Cys Pro Glu Ala 
        35                  40                  45              


Ile Leu Leu Thr Arg Lys Asp Thr Pro Tyr Cys Glu Thr Gly Leu Ile 
    50                  55                  60                  


Phe Leu Thr Leu Thr Lys Thr Ile Ala Asn Thr Tyr Phe Tyr Phe 
65                  70                  75                  


<210>  3334
<211>  562
<212>  PRT
<213>  homo sapiens

<400>  3334

Met Ser Asn Gln Tyr Gln Glu Glu Gly Cys Ser Glu Arg Pro Glu Cys 
1               5                   10                  15      


Lys Ser Lys Ser Pro Thr Leu Leu Ser Ser Tyr Cys Ile Asp Ser Ile 
            20                  25                  30          


Leu Gly Arg Arg Ser Pro Cys Lys Met Arg Leu Leu Gly Ala Ala Gln 
        35                  40                  45              


Ser Leu Pro Ala Pro Leu Thr Ser Arg Ala Asp Pro Glu Lys Ala Val 
    50                  55                  60                  


Gln Gly Ser Pro Lys Ser Ser Ser Ala Pro Phe Glu Ala Glu Leu His 
65                  70                  75                  80  


Leu Pro Pro Lys Leu Arg Arg Leu Tyr Gly Pro Gly Gly Gly Arg Leu 
                85                  90                  95      


Leu Gln Gly Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala 
            100                 105                 110         


Ala Ala Ala Thr Ala Thr Ala Gly Pro Arg Gly Glu Ala Pro Pro Pro 
        115                 120                 125             


Pro Pro Pro Thr Ala Arg Pro Gly Glu Arg Pro Asp Gly Ala Gly Ala 
    130                 135                 140                 


Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Trp Asp Thr Leu Lys 
145                 150                 155                 160 


Ile Ser Gln Ala Pro Gln Val Ser Ile Ser Arg Ser Lys Ser Tyr Arg 
                165                 170                 175     


Glu Asn Gly Ala Pro Phe Val Pro Pro Pro Pro Ala Leu Asp Glu Leu 
            180                 185                 190         


Gly Gly Pro Gly Gly Val Thr His Pro Glu Glu Arg Leu Gly Val Ala 
        195                 200                 205             


Gly Gly Pro Gly Ser Ala Pro Ala Ala Gly Gly Gly Thr Gly Thr Glu 
    210                 215                 220                 


Asp Asp Glu Glu Glu Leu Leu Glu Asp Glu Glu Asp Glu Asp Glu Glu 
225                 230                 235                 240 


Glu Glu Leu Leu Glu Asp Asp Glu Glu Glu Leu Leu Glu Asp Asp Ala 
                245                 250                 255     


Arg Ala Leu Leu Lys Glu Pro Arg Arg Cys Pro Val Ala Ala Thr Gly 
            260                 265                 270         


Ala Val Ala Ala Ala Ala Ala Ala Ala Val Ala Thr Glu Gly Gly Glu 
        275                 280                 285             


Leu Ser Pro Lys Glu Glu Leu Leu Leu His Pro Glu Asp Ala Glu Gly 
    290                 295                 300                 


Lys Asp Gly Glu Asp Ser Val Cys Leu Ser Ala Gly Ser Asp Ser Glu 
305                 310                 315                 320 


Glu Gly Leu Leu Lys Arg Lys Gln Arg Arg Tyr Arg Thr Thr Phe Thr 
                325                 330                 335     


Ser Tyr Gln Leu Glu Glu Leu Glu Arg Ala Phe Gln Lys Thr His Tyr 
            340                 345                 350         


Pro Asp Val Phe Thr Arg Glu Glu Leu Ala Met Arg Leu Asp Leu Thr 
        355                 360                 365             


Glu Ala Arg Val Gln Val Trp Phe Gln Asn Arg Arg Ala Lys Trp Arg 
    370                 375                 380                 


Lys Arg Glu Lys Ala Gly Ala Gln Thr His Pro Pro Gly Leu Pro Phe 
385                 390                 395                 400 


Pro Gly Pro Leu Ser Ala Thr His Pro Leu Ser Pro Tyr Leu Asp Ala 
                405                 410                 415     


Ser Pro Phe Pro Pro His His Pro Ala Leu Asp Ser Ala Trp Thr Ala 
            420                 425                 430         


Ala Ala Ala Ala Ala Ala Ala Ala Phe Pro Ser Leu Pro Pro Pro Pro 
        435                 440                 445             


Gly Ser Ala Ser Leu Pro Pro Ser Gly Ala Pro Leu Gly Leu Ser Thr 
    450                 455                 460                 


Phe Leu Gly Ala Ala Val Phe Arg His Pro Ala Phe Ile Ser Pro Ala 
465                 470                 475                 480 


Phe Gly Arg Leu Phe Ser Thr Met Ala Pro Leu Thr Ser Ala Ser Thr 
                485                 490                 495     


Ala Ala Ala Leu Leu Arg Gln Pro Thr Pro Ala Val Glu Gly Ala Val 
            500                 505                 510         


Ala Ser Gly Ala Leu Ala Asp Pro Ala Thr Ala Ala Ala Asp Arg Arg 
        515                 520                 525             


Ala Ser Ser Ile Ala Ala Leu Arg Leu Lys Ala Lys Glu His Ala Ala 
    530                 535                 540                 


Gln Leu Thr Gln Leu Asn Ile Leu Pro Gly Thr Ser Thr Gly Lys Glu 
545                 550                 555                 560 


Val Cys 
        


<210>  3335
<211>  289
<212>  PRT
<213>  homo sapiens

<400>  3335

Met Met Ser Tyr Leu Lys Gln Pro Pro Tyr Ala Val Asn Gly Leu Ser 
1               5                   10                  15      


Leu Thr Thr Ser Gly Met Asp Leu Leu His Pro Ser Val Gly Tyr Pro 
            20                  25                  30          


Ala Thr Pro Arg Lys Gln Arg Arg Glu Arg Thr Thr Phe Thr Arg Ala 
        35                  40                  45              


Gln Leu Asp Val Leu Glu Ala Leu Phe Ala Lys Thr Arg Tyr Pro Asp 
    50                  55                  60                  


Ile Phe Met Arg Glu Glu Val Ala Leu Lys Ile Asn Leu Pro Glu Ser 
65                  70                  75                  80  


Arg Val Gln Val Trp Phe Lys Asn Arg Arg Ala Lys Cys Arg Gln Gln 
                85                  90                  95      


Gln Gln Gln Gln Gln Asn Gly Gly Gln Asn Lys Val Arg Pro Ala Lys 
            100                 105                 110         


Lys Lys Thr Ser Pro Ala Arg Glu Val Ser Ser Glu Ser Gly Thr Ser 
        115                 120                 125             


Gly Gln Phe Thr Pro Pro Ser Ser Thr Ser Val Pro Thr Ile Ala Ser 
    130                 135                 140                 


Ser Ser Ala Pro Val Ser Ile Trp Ser Pro Ala Ser Ile Ser Pro Leu 
145                 150                 155                 160 


Ser Asp Pro Leu Ser Thr Ser Ser Ser Cys Met Gln Arg Ser Tyr Pro 
                165                 170                 175     


Met Thr Tyr Thr Gln Ala Ser Gly Tyr Ser Gln Gly Tyr Ala Gly Ser 
            180                 185                 190         


Thr Ser Tyr Phe Gly Gly Met Asp Cys Gly Ser Tyr Leu Thr Pro Met 
        195                 200                 205             


His His Gln Leu Pro Gly Pro Gly Ala Thr Leu Ser Pro Met Gly Thr 
    210                 215                 220                 


Asn Ala Val Thr Ser His Leu Asn Gln Ser Pro Ala Ser Leu Ser Thr 
225                 230                 235                 240 


Gln Gly Tyr Gly Ala Ser Ser Leu Gly Phe Asn Ser Thr Thr Asp Cys 
                245                 250                 255     


Leu Asp Tyr Lys Asp Gln Thr Ala Ser Trp Lys Leu Asn Phe Asn Ala 
            260                 265                 270         


Asp Cys Leu Asp Tyr Lys Asp Gln Thr Ser Ser Trp Lys Phe Gln Val 
        275                 280                 285             


Leu 
    


<210>  3336
<211>  1394
<212>  PRT
<213>  homo sapiens

<400>  3336

Met Ala Arg Arg His Glu Arg Val Thr Arg Arg Met Trp Thr Trp Ala 
1               5                   10                  15      


Pro Gly Leu Leu Met Met Thr Val Val Phe Trp Gly His Gln Gly Asn 
            20                  25                  30          


Gly Gln Gly Gln Gly Ser Arg Leu Arg Gln Glu Asp Phe Pro Pro Arg 
        35                  40                  45              


Ile Val Glu His Pro Ser Asp Val Ile Val Ser Lys Gly Glu Pro Thr 
    50                  55                  60                  


Thr Leu Asn Cys Lys Ala Glu Gly Arg Pro Thr Pro Thr Ile Glu Trp 
65                  70                  75                  80  


Tyr Lys Asp Gly Glu Arg Val Glu Thr Asp Lys Asp Asp Pro Arg Ser 
                85                  90                  95      


His Arg Met Leu Leu Pro Ser Gly Ser Leu Phe Phe Leu Arg Ile Val 
            100                 105                 110         


His Gly Arg Arg Ser Lys Pro Asp Glu Gly Ser Tyr Val Cys Val Ala 
        115                 120                 125             


Arg Asn Tyr Leu Gly Glu Ala Val Ser Arg Asn Ala Ser Leu Glu Val 
    130                 135                 140                 


Ala Leu Leu Arg Asp Asp Phe Arg Gln Asn Pro Thr Asp Val Val Val 
145                 150                 155                 160 


Ala Ala Gly Glu Pro Ala Ile Leu Glu Cys Gln Pro Pro Arg Gly His 
                165                 170                 175     


Pro Glu Pro Thr Ile Tyr Trp Lys Lys Asp Lys Val Arg Ile Asp Asp 
            180                 185                 190         


Lys Glu Glu Arg Ile Ser Ile Arg Gly Gly Lys Leu Met Ile Ser Asn 
        195                 200                 205             


Thr Arg Lys Ser Asp Ala Gly Met Tyr Thr Cys Val Gly Thr Asn Met 
    210                 215                 220                 


Val Gly Glu Arg Asp Ser Asp Pro Ala Glu Leu Thr Val Phe Glu Arg 
225                 230                 235                 240 


Pro Thr Phe Leu Arg Arg Pro Ile Asn Gln Val Val Leu Glu Glu Glu 
                245                 250                 255     


Ala Val Glu Phe Arg Cys Gln Val Gln Gly Asp Pro Gln Pro Thr Val 
            260                 265                 270         


Arg Trp Lys Lys Asp Asp Ala Asp Leu Pro Arg Gly Arg Tyr Asp Ile 
        275                 280                 285             


Lys Asp Asp Tyr Thr Leu Arg Ile Lys Lys Thr Met Ser Thr Asp Glu 
    290                 295                 300                 


Gly Thr Tyr Met Cys Ile Ala Glu Asn Arg Val Gly Lys Met Glu Ala 
305                 310                 315                 320 


Ser Ala Thr Leu Thr Val Arg Ala Pro Pro Gln Phe Val Val Arg Pro 
                325                 330                 335     


Arg Asp Gln Ile Val Ala Gln Gly Arg Thr Val Thr Phe Pro Cys Glu 
            340                 345                 350         


Thr Lys Gly Asn Pro Gln Pro Ala Val Phe Trp Gln Lys Glu Gly Ser 
        355                 360                 365             


Gln Asn Leu Leu Phe Pro Asn Gln Pro Gln Gln Pro Asn Ser Arg Cys 
    370                 375                 380                 


Ser Val Ser Pro Thr Gly Asp Leu Thr Ile Thr Asn Ile Gln Arg Ser 
385                 390                 395                 400 


Asp Ala Gly Tyr Tyr Ile Cys Gln Ala Leu Thr Val Ala Gly Ser Ile 
                405                 410                 415     


Leu Ala Lys Ala Gln Leu Glu Val Thr Asp Val Leu Thr Asp Arg Pro 
            420                 425                 430         


Pro Pro Ile Ile Leu Gln Gly Pro Ala Asn Gln Thr Leu Ala Val Asp 
        435                 440                 445             


Gly Thr Ala Leu Leu Lys Cys Lys Ala Thr Gly Asp Pro Leu Pro Val 
    450                 455                 460                 


Ile Ser Trp Leu Lys Glu Gly Phe Thr Phe Pro Gly Arg Asp Pro Arg 
465                 470                 475                 480 


Ala Thr Ile Gln Glu Gln Gly Thr Leu Gln Ile Lys Asn Leu Arg Ile 
                485                 490                 495     


Ser Asp Thr Gly Thr Tyr Thr Cys Val Ala Thr Ser Ser Ser Gly Glu 
            500                 505                 510         


Thr Ser Trp Ser Ala Val Leu Asp Val Thr Glu Ser Gly Ala Thr Ile 
        515                 520                 525             


Ser Lys Asn Tyr Asp Leu Ser Asp Leu Pro Gly Pro Pro Ser Lys Pro 
    530                 535                 540                 


Gln Val Thr Asp Val Thr Lys Asn Ser Val Thr Leu Ser Trp Gln Pro 
545                 550                 555                 560 


Gly Thr Pro Gly Thr Leu Pro Ala Ser Ala Tyr Ile Ile Glu Ala Phe 
                565                 570                 575     


Ser Gln Ser Val Ser Asn Ser Trp Gln Thr Val Ala Asn His Val Lys 
            580                 585                 590         


Thr Thr Leu Tyr Thr Val Arg Gly Leu Arg Pro Asn Thr Ile Tyr Leu 
        595                 600                 605             


Phe Met Val Arg Ala Ile Asn Pro Gln Gly Leu Ser Asp Pro Ser Pro 
    610                 615                 620                 


Met Ser Asp Pro Val Arg Thr Gln Asp Ile Ser Pro Pro Ala Gln Gly 
625                 630                 635                 640 


Val Asp His Arg Gln Val Gln Lys Glu Leu Gly Asp Val Leu Val Arg 
                645                 650                 655     


Leu His Asn Pro Val Val Leu Thr Pro Thr Thr Val Gln Val Thr Trp 
            660                 665                 670         


Thr Val Asp Arg Gln Pro Gln Phe Ile Gln Gly Tyr Arg Val Met Tyr 
        675                 680                 685             


Arg Gln Thr Ser Gly Leu Gln Ala Thr Ser Ser Trp Gln Asn Leu Asp 
    690                 695                 700                 


Ala Lys Val Pro Thr Glu Arg Ser Ala Val Leu Val Asn Leu Lys Lys 
705                 710                 715                 720 


Gly Val Thr Tyr Glu Ile Lys Val Arg Pro Tyr Phe Asn Glu Phe Gln 
                725                 730                 735     


Gly Met Asp Ser Glu Ser Lys Thr Val Arg Thr Thr Glu Glu Ala Pro 
            740                 745                 750         


Ser Ala Pro Pro Gln Ser Val Thr Val Leu Thr Val Gly Ser Tyr Asn 
        755                 760                 765             


Ser Thr Ser Ile Ser Val Ser Trp Asp Pro Pro Pro Pro Asp His Gln 
    770                 775                 780                 


Asn Gly Ile Ile Gln Glu Tyr Lys Ile Trp Cys Leu Gly Asn Glu Thr 
785                 790                 795                 800 


Arg Phe His Ile Asn Lys Thr Val Asp Ala Ala Ile Arg Ser Val Ile 
                805                 810                 815     


Ile Gly Gly Leu Phe Pro Gly Ile Gln Tyr Arg Val Glu Val Ala Ala 
            820                 825                 830         


Ser Thr Ser Ala Gly Val Gly Val Lys Ser Glu Pro Gln Pro Ile Ile 
        835                 840                 845             


Ile Gly Arg Arg Asn Glu Val Val Ile Thr Glu Asn Asn Asn Ser Ile 
    850                 855                 860                 


Thr Glu Gln Ile Thr Asp Val Val Lys Gln Pro Ala Phe Ile Ala Gly 
865                 870                 875                 880 


Ile Gly Gly Ala Cys Trp Val Ile Leu Met Gly Phe Ser Ile Trp Leu 
                885                 890                 895     


Tyr Trp Arg Arg Lys Lys Arg Lys Gly Leu Ser Asn Tyr Ala Val Thr 
            900                 905                 910         


Phe Gln Arg Gly Asp Gly Gly Leu Met Ser Asn Gly Ser Arg Pro Gly 
        915                 920                 925             


Leu Leu Asn Ala Gly Asp Pro Ser Tyr Pro Trp Leu Ala Asp Ser Trp 
    930                 935                 940                 


Pro Ala Thr Ser Leu Pro Val Asn Asn Ser Asn Ser Gly Pro Asn Glu 
945                 950                 955                 960 


Ile Gly Asn Phe Gly Arg Gly Asp Val Leu Pro Pro Val Pro Gly Gln 
                965                 970                 975     


Gly Asp Lys Thr Ala Thr Met Leu Ser Asp Gly Ala Ile Tyr Ser Ser 
            980                 985                 990         


Ile Asp Phe Thr Thr Lys Thr Ser  Tyr Asn Ser Ser Ser  Gln Ile Thr 
        995                 1000                 1005             


Gln Ala  Thr Pro Tyr Ala Thr  Thr Gln Ile Leu His  Ser Asn Ser 
    1010                 1015                 1020             


Ile His  Glu Leu Ala Val Asp  Leu Pro Asp Pro Gln  Trp Lys Ser 
    1025                 1030                 1035             


Ser Ile  Gln Gln Lys Thr Asp  Leu Met Gly Phe Gly  Tyr Ser Leu 
    1040                 1045                 1050             


Pro Asp  Gln Asn Lys Gly Asn  Asn Gly Gly Lys Gly  Gly Lys Lys 
    1055                 1060                 1065             


Lys Lys  Asn Lys Asn Ser Ser  Lys Pro Gln Lys Asn  Asn Gly Ser 
    1070                 1075                 1080             


Thr Trp  Ala Asn Val Pro Leu  Pro Pro Pro Pro Val  Gln Pro Leu 
    1085                 1090                 1095             


Pro Gly  Thr Glu Leu Glu His  Tyr Ala Val Glu Gln  Gln Glu Asn 
    1100                 1105                 1110             


Gly Tyr  Asp Ser Asp Ser Trp  Cys Pro Pro Leu Pro  Val Gln Thr 
    1115                 1120                 1125             


Tyr Leu  His Gln Gly Leu Glu  Asp Glu Leu Glu Glu  Asp Asp Asp 
    1130                 1135                 1140             


Arg Val  Pro Thr Pro Pro Val  Arg Gly Val Ala Ser  Ser Pro Ala 
    1145                 1150                 1155             


Ile Ser  Phe Gly Gln Gln Ser  Thr Ala Thr Leu Thr  Pro Ser Pro 
    1160                 1165                 1170             


Arg Glu  Glu Met Gln Pro Met  Leu Gln Ala His Leu  Asp Glu Leu 
    1175                 1180                 1185             


Thr Arg  Ala Tyr Gln Phe Asp  Ile Ala Lys Gln Thr  Trp His Ile 
    1190                 1195                 1200             


Gln Ser  Asn Asn Gln Pro Pro  Gln Pro Pro Val Pro  Pro Leu Gly 
    1205                 1210                 1215             


Tyr Val  Ser Gly Ala Leu Ile  Ser Asp Leu Glu Thr  Asp Val Ala 
    1220                 1225                 1230             


Asp Asp  Asp Ala Asp Asp Glu  Glu Glu Ala Leu Glu  Ile Pro Arg 
    1235                 1240                 1245             


Pro Leu  Arg Ala Leu Asp Gln  Thr Pro Gly Ser Ser  Met Asp Asn 
    1250                 1255                 1260             


Leu Asp  Ser Ser Val Thr Gly  Lys Ala Phe Thr Ser  Ser Gln Arg 
    1265                 1270                 1275             


Pro Arg  Pro Thr Ser Pro Phe  Ser Thr Asp Ser Asn  Thr Ser Ala 
    1280                 1285                 1290             


Ala Leu  Ser Gln Ser Gln Arg  Pro Arg Pro Thr Lys  Lys His Lys 
    1295                 1300                 1305             


Gly Gly  Arg Met Asp Gln Gln  Pro Ala Leu Pro His  Arg Arg Glu 
    1310                 1315                 1320             


Gly Met  Thr Asp Glu Glu Ala  Leu Val Pro Tyr Ser  Lys Pro Ser 
    1325                 1330                 1335             


Phe Pro  Ser Pro Gly Gly His  Ser Ser Ser Gly Thr  Ala Ser Ser 
    1340                 1345                 1350             


Lys Gly  Ser Thr Gly Pro Arg  Lys Thr Glu Val Leu  Arg Ala Gly 
    1355                 1360                 1365             


His Gln  Arg Asn Ala Ser Asp  Leu Leu Asp Ile Gly  Tyr Met Gly 
    1370                 1375                 1380             


Ser Asn  Ser Gln Gly Gln Phe  Thr Gly Glu Leu 
    1385                 1390                 


<210>  3337
<211>  2825
<212>  PRT
<213>  homo sapiens

<400>  3337

Met Tyr Ala Ser Leu Gly Ser Gly Pro Val Ala Pro Leu Pro Ala Ser 
1               5                   10                  15      


Val Pro Pro Ser Val Leu Gly Ser Trp Ser Thr Gly Gly Ser Arg Ser 
            20                  25                  30          


Cys Val Arg Gln Glu Thr Lys Ser Pro Gly Gly Ala Arg Thr Ser Gly 
        35                  40                  45              


His Trp Ala Ser Val Trp Gln Glu Val Leu Lys Gln Leu Gln Gly Ser 
    50                  55                  60                  


Ile Glu Asp Glu Ala Met Ala Ser Ser Gly Gln Ile Asp Leu Leu Glu 
65                  70                  75                  80  


Arg Leu Lys Glu Leu Asn Leu Asp Ser Ser Asn Phe Pro Gly Val Lys 
                85                  90                  95      


Leu Arg Ser Lys Met Ser Leu Arg Ser Tyr Gly Ser Arg Glu Gly Ser 
            100                 105                 110         


Val Ser Ser Arg Ser Gly Glu Cys Ser Pro Val Pro Met Gly Ser Phe 
        115                 120                 125             


Pro Arg Arg Gly Phe Val Asn Gly Ser Arg Glu Ser Thr Gly Tyr Leu 
    130                 135                 140                 


Glu Glu Leu Glu Lys Glu Arg Ser Leu Leu Leu Ala Asp Leu Asp Lys 
145                 150                 155                 160 


Glu Glu Lys Glu Lys Asp Trp Tyr Tyr Ala Gln Leu Gln Asn Leu Thr 
                165                 170                 175     


Lys Arg Ile Asp Ser Leu Pro Leu Thr Glu Asn Phe Ser Leu Gln Thr 
            180                 185                 190         


Asp Met Thr Arg Arg Gln Leu Glu Tyr Glu Ala Arg Gln Ile Arg Val 
        195                 200                 205             


Ala Met Glu Glu Gln Leu Gly Thr Cys Gln Asp Met Glu Lys Arg Ala 
    210                 215                 220                 


Gln Arg Ser Ser Gln Asn Lys His Glu Thr Gly Ser His Asp Ala Glu 
225                 230                 235                 240 


Arg Gln Asn Glu Gly Gln Gly Val Gly Glu Ile Asn Met Ala Thr Ser 
                245                 250                 255     


Gly Asn Gly Gln Gly Ser Thr Thr Arg Met Asp His Glu Thr Ala Ser 
            260                 265                 270         


Val Leu Ser Ser Ser Ser Thr His Ser Ala Pro Arg Arg Leu Thr Ser 
        275                 280                 285             


His Leu Gly Thr Lys Val Glu Met Val Tyr Ser Leu Leu Ser Met Leu 
    290                 295                 300                 


Gly Thr His Asp Lys Asp Asp Met Ser Arg Thr Leu Leu Ala Met Ser 
305                 310                 315                 320 


Ser Ser Gln Asp Ser Cys Ile Ser Met Arg Gln Ser Gly Cys Leu Pro 
                325                 330                 335     


Leu Leu Ile Gln Leu Leu His Gly Asn Asp Lys Asp Ser Val Leu Leu 
            340                 345                 350         


Gly Asn Ser Arg Gly Ser Lys Glu Ala Arg Ala Arg Ala Ser Ala Ala 
        355                 360                 365             


Leu His Asn Ile Ile His Ser Gln Pro Asp Asp Lys Arg Gly Arg Arg 
    370                 375                 380                 


Glu Ile Arg Val Leu His Leu Leu Glu Gln Ile Arg Ala Tyr Cys Glu 
385                 390                 395                 400 


Thr Cys Trp Glu Trp Gln Glu Ala His Glu Pro Gly Met Asp Gln Asp 
                405                 410                 415     


Lys Asn Pro Met Pro Ala Pro Val Glu His Gln Ile Cys Pro Ala Val 
            420                 425                 430         


Cys Val Leu Met Lys Leu Ser Phe Asp Glu Glu His Arg His Ala Met 
        435                 440                 445             


Asn Glu Leu Gly Gly Leu Gln Ala Ile Ala Glu Leu Leu Gln Val Asp 
    450                 455                 460                 


Cys Glu Met Tyr Gly Leu Thr Asn Asp His Tyr Ser Ile Thr Leu Arg 
465                 470                 475                 480 


Arg Tyr Ala Gly Met Ala Leu Thr Asn Leu Thr Phe Gly Asp Val Ala 
                485                 490                 495     


Asn Lys Ala Thr Leu Cys Ser Met Lys Gly Cys Met Arg Ala Leu Val 
            500                 505                 510         


Ala Gln Leu Lys Ser Glu Ser Glu Asp Leu Gln Gln Val Ile Ala Ser 
        515                 520                 525             


Val Leu Arg Asn Leu Ser Trp Arg Ala Asp Val Asn Ser Lys Lys Thr 
    530                 535                 540                 


Leu Arg Glu Val Gly Ser Val Lys Ala Leu Met Glu Cys Ala Leu Glu 
545                 550                 555                 560 


Val Lys Lys Glu Ser Thr Leu Lys Ser Val Leu Ser Ala Leu Trp Asn 
                565                 570                 575     


Leu Ser Ala His Cys Thr Glu Asn Lys Ala Asp Ile Cys Ala Val Asp 
            580                 585                 590         


Gly Ala Leu Ala Phe Leu Val Gly Thr Leu Thr Tyr Arg Ser Gln Thr 
        595                 600                 605             


Asn Thr Leu Ala Ile Ile Glu Ser Gly Gly Gly Ile Leu Arg Asn Val 
    610                 615                 620                 


Ser Ser Leu Ile Ala Thr Asn Glu Asp His Arg Gln Ile Leu Arg Glu 
625                 630                 635                 640 


Asn Asn Cys Leu Gln Thr Leu Leu Gln His Leu Lys Ser His Ser Leu 
                645                 650                 655     


Thr Ile Val Ser Asn Ala Cys Gly Thr Leu Trp Asn Leu Ser Ala Arg 
            660                 665                 670         


Asn Pro Lys Asp Gln Glu Ala Leu Trp Asp Met Gly Ala Val Ser Met 
        675                 680                 685             


Leu Lys Asn Leu Ile His Ser Lys His Lys Met Ile Ala Met Gly Ser 
    690                 695                 700                 


Ala Ala Ala Leu Arg Asn Leu Met Ala Asn Arg Pro Ala Lys Tyr Lys 
705                 710                 715                 720 


Asp Ala Asn Ile Met Ser Pro Gly Ser Ser Leu Pro Ser Leu His Val 
                725                 730                 735     


Arg Lys Gln Lys Ala Leu Glu Ala Glu Leu Asp Ala Gln His Leu Ser 
            740                 745                 750         


Glu Thr Phe Asp Asn Ile Asp Asn Leu Ser Pro Lys Ala Ser His Arg 
        755                 760                 765             


Ser Lys Gln Arg His Lys Gln Ser Leu Tyr Gly Asp Tyr Val Phe Asp 
    770                 775                 780                 


Thr Asn Arg His Asp Asp Asn Arg Ser Asp Asn Phe Asn Thr Gly Asn 
785                 790                 795                 800 


Met Thr Val Leu Ser Pro Tyr Leu Asn Thr Thr Val Leu Pro Ser Ser 
                805                 810                 815     


Ser Ser Ser Arg Gly Ser Leu Asp Ser Ser Arg Ser Glu Lys Asp Arg 
            820                 825                 830         


Ser Leu Glu Arg Glu Arg Gly Ile Gly Leu Gly Asn Tyr His Pro Ala 
        835                 840                 845             


Thr Glu Asn Pro Gly Thr Ser Ser Lys Arg Gly Leu Gln Ile Ser Thr 
    850                 855                 860                 


Thr Ala Ala Gln Ile Ala Lys Val Met Glu Glu Val Ser Ala Ile His 
865                 870                 875                 880 


Thr Ser Gln Glu Asp Arg Ser Ser Gly Ser Thr Thr Glu Leu His Cys 
                885                 890                 895     


Val Thr Asp Glu Arg Asn Ala Leu Arg Arg Ser Ser Ala Ala His Thr 
            900                 905                 910         


His Ser Asn Thr Tyr Asn Phe Thr Lys Ser Glu Asn Ser Asn Arg Thr 
        915                 920                 925             


Cys Ser Met Pro Tyr Ala Lys Leu Glu Tyr Lys Arg Ser Ser Asn Asp 
    930                 935                 940                 


Ser Leu Asn Ser Val Ser Ser Ser Asp Gly Tyr Gly Lys Arg Gly Gln 
945                 950                 955                 960 


Met Lys Pro Ser Ile Glu Ser Tyr Ser Glu Asp Asp Glu Ser Lys Phe 
                965                 970                 975     


Cys Ser Tyr Gly Gln Tyr Pro Ala Asp Leu Ala His Lys Ile His Ser 
            980                 985                 990         


Ala Asn His Met Asp Asp Asn Asp  Gly Glu Leu Asp Thr  Pro Ile Asn 
        995                 1000                 1005             


Tyr Ser  Leu Lys Tyr Ser Asp  Glu Gln Leu Asn Ser  Gly Arg Gln 
    1010                 1015                 1020             


Ser Pro  Ser Gln Asn Glu Arg  Trp Ala Arg Pro Lys  His Ile Ile 
    1025                 1030                 1035             


Glu Asp  Glu Ile Lys Gln Ser  Glu Gln Arg Gln Ser  Arg Asn Gln 
    1040                 1045                 1050             


Ser Thr  Thr Tyr Pro Val Tyr  Thr Glu Ser Thr Asp  Asp Lys His 
    1055                 1060                 1065             


Leu Lys  Phe Gln Pro His Phe  Gly Gln Gln Glu Cys  Val Ser Pro 
    1070                 1075                 1080             


Tyr Arg  Ser Arg Gly Ala Asn  Gly Ser Glu Thr Asn  Arg Val Gly 
    1085                 1090                 1095             


Ser Asn  His Gly Ile Asn Gln  Asn Val Ser Gln Ser  Leu Cys Gln 
    1100                 1105                 1110             


Glu Asp  Asp Tyr Glu Asp Asp  Lys Pro Thr Asn Tyr  Ser Glu Arg 
    1115                 1120                 1125             


Tyr Ser  Glu Glu Glu Gln His  Glu Glu Glu Glu Arg  Pro Thr Asn 
    1130                 1135                 1140             


Tyr Ser  Ile Lys Tyr Asn Glu  Glu Lys Arg His Val  Asp Gln Pro 
    1145                 1150                 1155             


Ile Asp  Tyr Ser Leu Lys Tyr  Ala Thr Asp Ile Pro  Ser Ser Gln 
    1160                 1165                 1170             


Lys Gln  Ser Phe Ser Phe Ser  Lys Ser Ser Ser Gly  Gln Ser Ser 
    1175                 1180                 1185             


Lys Thr  Glu His Met Ser Ser  Ser Ser Glu Asn Thr  Ser Thr Pro 
    1190                 1195                 1200             


Ser Ser  Asn Ala Lys Arg Gln  Asn Gln Leu His Pro  Ser Ser Ala 
    1205                 1210                 1215             


Gln Ser  Arg Ser Gly Gln Pro  Gln Lys Ala Ala Thr  Cys Lys Val 
    1220                 1225                 1230             


Ser Ser  Ile Asn Gln Glu Thr  Ile Gln Thr Tyr Cys  Val Glu Asp 
    1235                 1240                 1245             


Thr Pro  Ile Cys Phe Ser Arg  Cys Ser Ser Leu Ser  Ser Leu Ser 
    1250                 1255                 1260             


Ser Ala  Glu Asp Glu Ile Gly  Cys Asn Gln Thr Thr  Gln Glu Ala 
    1265                 1270                 1275             


Asp Ser  Ala Asn Thr Leu Gln  Ile Ala Glu Ile Lys  Glu Lys Ile 
    1280                 1285                 1290             


Gly Thr  Arg Ser Ala Glu Asp  Pro Val Ser Glu Val  Pro Ala Val 
    1295                 1300                 1305             


Ser Gln  His Pro Arg Thr Lys  Ser Ser Arg Leu Gln  Gly Ser Ser 
    1310                 1315                 1320             


Leu Ser  Ser Glu Ser Ala Arg  His Lys Ala Val Glu  Phe Ser Ser 
    1325                 1330                 1335             


Gly Ala  Lys Ser Pro Ser Lys  Ser Gly Ala Gln Thr  Pro Lys Ser 
    1340                 1345                 1350             


Pro Pro  Glu His Tyr Val Gln  Glu Thr Pro Leu Met  Phe Ser Arg 
    1355                 1360                 1365             


Cys Thr  Ser Val Ser Ser Leu  Asp Ser Phe Glu Ser  Arg Ser Ile 
    1370                 1375                 1380             


Ala Ser  Ser Val Gln Ser Glu  Pro Cys Ser Gly Met  Val Ser Gly 
    1385                 1390                 1395             


Ile Ile  Ser Pro Ser Asp Leu  Pro Asp Ser Pro Gly  Gln Thr Met 
    1400                 1405                 1410             


Pro Pro  Ser Arg Ser Lys Thr  Pro Pro Pro Pro Pro  Gln Thr Ala 
    1415                 1420                 1425             


Gln Thr  Lys Arg Glu Val Pro  Lys Asn Lys Ala Pro  Thr Ala Glu 
    1430                 1435                 1440             


Lys Arg  Glu Ser Gly Pro Lys  Gln Ala Ala Val Asn  Ala Ala Val 
    1445                 1450                 1455             


Gln Arg  Val Gln Val Leu Pro  Asp Ala Asp Thr Leu  Leu His Phe 
    1460                 1465                 1470             


Ala Thr  Glu Ser Thr Pro Asp  Gly Phe Ser Cys Ser  Ser Ser Leu 
    1475                 1480                 1485             


Ser Ala  Leu Ser Leu Asp Glu  Pro Phe Ile Gln Lys  Asp Val Glu 
    1490                 1495                 1500             


Leu Arg  Ile Met Pro Pro Val  Gln Glu Asn Asp Asn  Gly Asn Glu 
    1505                 1510                 1515             


Thr Glu  Ser Glu Gln Pro Lys  Glu Ser Asn Glu Asn  Gln Glu Lys 
    1520                 1525                 1530             


Glu Ala  Glu Lys Thr Ile Asp  Ser Glu Lys Asp Leu  Leu Asp Asp 
    1535                 1540                 1545             


Ser Asp  Asp Asp Asp Ile Glu  Ile Leu Glu Glu Cys  Ile Ile Ser 
    1550                 1555                 1560             


Ala Met  Pro Thr Lys Ser Ser  Arg Lys Ala Lys Lys  Pro Ala Gln 
    1565                 1570                 1575             


Thr Ala  Ser Lys Leu Pro Pro  Pro Val Ala Arg Lys  Pro Ser Gln 
    1580                 1585                 1590             


Leu Pro  Val Tyr Lys Leu Leu  Pro Ser Gln Asn Arg  Leu Gln Pro 
    1595                 1600                 1605             


Gln Lys  His Val Ser Phe Thr  Pro Gly Asp Asp Met  Pro Arg Val 
    1610                 1615                 1620             


Tyr Cys  Val Glu Gly Thr Pro  Ile Asn Phe Ser Thr  Ala Thr Ser 
    1625                 1630                 1635             


Leu Ser  Asp Leu Thr Ile Glu  Ser Pro Pro Asn Glu  Leu Ala Ala 
    1640                 1645                 1650             


Gly Glu  Gly Val Arg Gly Gly  Ala Gln Ser Gly Glu  Phe Glu Lys 
    1655                 1660                 1665             


Arg Asp  Thr Ile Pro Thr Glu  Gly Arg Ser Thr Asp  Glu Ala Gln 
    1670                 1675                 1680             


Gly Gly  Lys Thr Ser Ser Val  Thr Ile Pro Glu Leu  Asp Asp Asn 
    1685                 1690                 1695             


Lys Ala  Glu Glu Gly Asp Ile  Leu Ala Glu Cys Ile  Asn Ser Ala 
    1700                 1705                 1710             


Met Pro  Lys Gly Lys Ser His  Lys Pro Phe Arg Val  Lys Lys Ile 
    1715                 1720                 1725             


Met Asp  Gln Val Gln Gln Ala  Ser Ala Ser Ser Ser  Ala Pro Asn 
    1730                 1735                 1740             


Lys Asn  Gln Leu Asp Gly Lys  Lys Lys Lys Pro Thr  Ser Pro Val 
    1745                 1750                 1755             


Lys Pro  Ile Pro Gln Asn Thr  Glu Tyr Arg Thr Arg  Val Arg Lys 
    1760                 1765                 1770             


Asn Ala  Asp Ser Lys Asn Asn  Leu Asn Ala Glu Arg  Val Phe Ser 
    1775                 1780                 1785             


Asp Asn  Lys Asp Ser Lys Lys  Gln Asn Leu Lys Asn  Asn Ser Lys 
    1790                 1795                 1800             


Val Phe  Asn Asp Lys Leu Pro  Asn Asn Glu Asp Arg  Val Arg Gly 
    1805                 1810                 1815             


Ser Phe  Ala Phe Asp Ser Pro  His His Tyr Thr Pro  Ile Glu Gly 
    1820                 1825                 1830             


Thr Pro  Tyr Cys Phe Ser Arg  Asn Asp Ser Leu Ser  Ser Leu Asp 
    1835                 1840                 1845             


Phe Asp  Asp Asp Asp Val Asp  Leu Ser Arg Glu Lys  Ala Glu Leu 
    1850                 1855                 1860             


Arg Lys  Ala Lys Glu Asn Lys  Glu Ser Glu Ala Lys  Val Thr Ser 
    1865                 1870                 1875             


His Thr  Glu Leu Thr Ser Asn  Gln Gln Ser Ala Asn  Lys Thr Gln 
    1880                 1885                 1890             


Ala Ile  Ala Lys Gln Pro Ile  Asn Arg Gly Gln Pro  Lys Pro Ile 
    1895                 1900                 1905             


Leu Gln  Lys Gln Ser Thr Phe  Pro Gln Ser Ser Lys  Asp Ile Pro 
    1910                 1915                 1920             


Asp Arg  Gly Ala Ala Thr Asp  Glu Lys Leu Gln Asn  Phe Ala Ile 
    1925                 1930                 1935             


Glu Asn  Thr Pro Val Cys Phe  Ser His Asn Ser Ser  Leu Ser Ser 
    1940                 1945                 1950             


Leu Ser  Asp Ile Asp Gln Glu  Asn Asn Asn Lys Glu  Asn Glu Pro 
    1955                 1960                 1965             


Ile Lys  Glu Thr Glu Pro Pro  Asp Ser Gln Gly Glu  Pro Ser Lys 
    1970                 1975                 1980             


Pro Gln  Ala Ser Gly Tyr Ala  Pro Lys Ser Phe His  Val Glu Asp 
    1985                 1990                 1995             


Thr Pro  Val Cys Phe Ser Arg  Asn Ser Ser Leu Ser  Ser Leu Ser 
    2000                 2005                 2010             


Ile Asp  Ser Glu Asp Asp Leu  Leu Gln Glu Cys Ile  Ser Ser Ala 
    2015                 2020                 2025             


Met Pro  Lys Lys Lys Lys Pro  Ser Arg Leu Lys Gly  Asp Asn Glu 
    2030                 2035                 2040             


Lys His  Ser Pro Arg Asn Met  Gly Gly Ile Leu Gly  Glu Asp Leu 
    2045                 2050                 2055             


Thr Leu  Asp Leu Lys Asp Ile  Gln Arg Pro Asp Ser  Glu His Gly 
    2060                 2065                 2070             


Leu Ser  Pro Asp Ser Glu Asn  Phe Asp Trp Lys Ala  Ile Gln Glu 
    2075                 2080                 2085             


Gly Ala  Asn Ser Ile Val Ser  Ser Leu His Gln Ala  Ala Ala Ala 
    2090                 2095                 2100             


Ala Cys  Leu Ser Arg Gln Ala  Ser Ser Asp Ser Asp  Ser Ile Leu 
    2105                 2110                 2115             


Ser Leu  Lys Ser Gly Ile Ser  Leu Gly Ser Pro Phe  His Leu Thr 
    2120                 2125                 2130             


Pro Asp  Gln Glu Glu Lys Pro  Phe Thr Ser Asn Lys  Gly Pro Arg 
    2135                 2140                 2145             


Ile Leu  Lys Pro Gly Glu Lys  Ser Thr Leu Glu Thr  Lys Lys Ile 
    2150                 2155                 2160             


Glu Ser  Glu Ser Lys Gly Ile  Lys Gly Gly Lys Lys  Val Tyr Lys 
    2165                 2170                 2175             


Ser Leu  Ile Thr Gly Lys Val  Arg Ser Asn Ser Glu  Ile Ser Gly 
    2180                 2185                 2190             


Gln Met  Lys Gln Pro Leu Gln  Ala Asn Met Pro Ser  Ile Ser Arg 
    2195                 2200                 2205             


Gly Arg  Thr Met Ile His Ile  Pro Gly Val Arg Asn  Ser Ser Ser 
    2210                 2215                 2220             


Ser Thr  Ser Pro Val Ser Lys  Lys Gly Pro Pro Leu  Lys Thr Pro 
    2225                 2230                 2235             


Ala Ser  Lys Ser Pro Ser Glu  Gly Gln Thr Ala Thr  Thr Ser Pro 
    2240                 2245                 2250             


Arg Gly  Ala Lys Pro Ser Val  Lys Ser Glu Leu Ser  Pro Val Ala 
    2255                 2260                 2265             


Arg Gln  Thr Ser Gln Ile Gly  Gly Ser Ser Lys Ala  Pro Ser Arg 
    2270                 2275                 2280             


Ser Gly  Ser Arg Asp Ser Thr  Pro Ser Arg Pro Ala  Gln Gln Pro 
    2285                 2290                 2295             


Leu Ser  Arg Pro Ile Gln Ser  Pro Gly Arg Asn Ser  Ile Ser Pro 
    2300                 2305                 2310             


Gly Arg  Asn Gly Ile Ser Pro  Pro Asn Lys Leu Ser  Gln Leu Pro 
    2315                 2320                 2325             


Arg Thr  Ser Ser Pro Ser Thr  Ala Ser Thr Lys Ser  Ser Gly Ser 
    2330                 2335                 2340             


Gly Lys  Met Ser Tyr Thr Ser  Pro Gly Arg Gln Met  Ser Gln Gln 
    2345                 2350                 2355             


Asn Leu  Thr Lys Gln Thr Gly  Leu Ser Lys Asn Ala  Ser Ser Ile 
    2360                 2365                 2370             


Pro Arg  Ser Glu Ser Ala Ser  Lys Gly Leu Asn Gln  Met Asn Asn 
    2375                 2380                 2385             


Gly Asn  Gly Ala Asn Lys Lys  Val Glu Leu Ser Arg  Met Ser Ser 
    2390                 2395                 2400             


Thr Lys  Ser Ser Gly Ser Glu  Ser Asp Arg Ser Glu  Arg Pro Val 
    2405                 2410                 2415             


Leu Val  Arg Gln Ser Thr Phe  Ile Lys Glu Ala Pro  Ser Pro Thr 
    2420                 2425                 2430             


Leu Arg  Arg Lys Leu Glu Glu  Ser Ala Ser Phe Glu  Ser Leu Ser 
    2435                 2440                 2445             


Pro Ser  Ser Arg Pro Ala Ser  Pro Thr Arg Ser Gln  Ala Gln Thr 
    2450                 2455                 2460             


Pro Val  Leu Ser Pro Ser Leu  Pro Asp Met Ser Leu  Ser Thr His 
    2465                 2470                 2475             


Ser Ser  Val Gln Ala Gly Gly  Trp Arg Lys Leu Pro  Pro Asn Leu 
    2480                 2485                 2490             


Ser Pro  Thr Ile Glu Tyr Asn  Asp Gly Arg Pro Ala  Lys Arg His 
    2495                 2500                 2505             


Asp Ile  Ala Arg Ser His Ser  Glu Ser Pro Ser Arg  Leu Pro Ile 
    2510                 2515                 2520             


Asn Arg  Ser Gly Thr Trp Lys  Arg Glu His Ser Lys  His Ser Ser 
    2525                 2530                 2535             


Ser Leu  Pro Arg Val Ser Thr  Trp Arg Arg Thr Gly  Ser Ser Ser 
    2540                 2545                 2550             


Ser Ile  Leu Ser Ala Ser Ser  Glu Ser Ser Glu Lys  Ala Lys Ser 
    2555                 2560                 2565             


Glu Asp  Glu Lys His Val Asn  Ser Ile Ser Gly Thr  Lys Gln Ser 
    2570                 2575                 2580             


Lys Glu  Asn Gln Val Ser Ala  Lys Gly Thr Trp Arg  Lys Ile Lys 
    2585                 2590                 2595             


Glu Asn  Glu Phe Ser Pro Thr  Asn Ser Thr Ser Gln  Thr Val Ser 
    2600                 2605                 2610             


Ser Gly  Ala Thr Asn Gly Ala  Glu Ser Lys Thr Leu  Ile Tyr Gln 
    2615                 2620                 2625             


Met Ala  Pro Ala Val Ser Lys  Thr Glu Asp Val Trp  Val Arg Ile 
    2630                 2635                 2640             


Glu Asp  Cys Pro Ile Asn Asn  Pro Arg Ser Gly Arg  Ser Pro Thr 
    2645                 2650                 2655             


Gly Asn  Thr Pro Pro Val Ile  Asp Ser Val Ser Glu  Lys Ala Asn 
    2660                 2665                 2670             


Pro Asn  Ile Lys Asp Ser Lys  Asp Asn Gln Ala Lys  Gln Asn Val 
    2675                 2680                 2685             


Gly Asn  Gly Ser Val Pro Met  Arg Thr Val Gly Leu  Glu Asn Arg 
    2690                 2695                 2700             


Leu Asn  Ser Phe Ile Gln Val  Asp Ala Pro Asp Gln  Lys Gly Thr 
    2705                 2710                 2715             


Glu Ile  Lys Pro Gly Gln Asn  Asn Pro Val Pro Val  Ser Glu Thr 
    2720                 2725                 2730             


Asn Glu  Ser Ser Ile Val Glu  Arg Thr Pro Phe Ser  Ser Ser Ser 
    2735                 2740                 2745             


Ser Ser  Lys His Ser Ser Pro  Ser Gly Thr Val Ala  Ala Arg Val 
    2750                 2755                 2760             


Thr Pro  Phe Asn Tyr Asn Pro  Ser Pro Arg Lys Ser  Ser Ala Asp 
    2765                 2770                 2775             


Ser Thr  Ser Ala Arg Pro Ser  Gln Ile Pro Thr Pro  Val Asn Asn 
    2780                 2785                 2790             


Asn Thr  Lys Lys Arg Asp Ser  Lys Thr Asp Ser Thr  Glu Ser Ser 
    2795                 2800                 2805             


Gly Thr  Gln Ser Pro Lys Arg  His Ser Gly Ser Tyr  Leu Val Thr 
    2810                 2815                 2820             


Ser Val  
    2825 


<210>  3338
<211>  388
<212>  PRT
<213>  homo sapiens

<400>  3338

Met Leu Asn Gly Thr Thr Leu Glu Ala Ala Met Leu Phe His Gly Ile 
1               5                   10                  15      


Ser Gly Gly His Ile Gln Gly Ile Met Glu Glu Met Glu Arg Arg Ser 
            20                  25                  30          


Lys Thr Glu Ala Arg Leu Ala Lys Gly Ala Gln Leu Asn Gly Arg Asp 
        35                  40                  45              


Ala Gly Met Pro Pro Leu Ser Pro Glu Lys Pro Ala Leu Cys Ala Gly 
    50                  55                  60                  


Cys Gly Gly Lys Ile Ser Asp Arg Tyr Tyr Leu Leu Ala Val Asp Lys 
65                  70                  75                  80  


Gln Trp His Leu Arg Cys Leu Lys Cys Cys Glu Cys Lys Leu Ala Leu 
                85                  90                  95      


Glu Ser Glu Leu Thr Cys Phe Ala Lys Asp Gly Ser Ile Tyr Cys Lys 
            100                 105                 110         


Glu Asp Tyr Tyr Arg Arg Phe Ser Val Gln Arg Cys Ala Arg Cys His 
        115                 120                 125             


Leu Gly Ile Ser Ala Ser Glu Met Val Met Arg Ala Arg Asp Ser Val 
    130                 135                 140                 


Tyr His Leu Ser Cys Phe Thr Cys Ser Thr Cys Asn Lys Thr Leu Thr 
145                 150                 155                 160 


Thr Gly Asp His Phe Gly Met Lys Asp Ser Leu Val Tyr Cys Arg Ala 
                165                 170                 175     


His Phe Glu Thr Leu Leu Gln Gly Glu Tyr Pro Pro Gln Leu Ser Tyr 
            180                 185                 190         


Thr Glu Leu Ala Ala Lys Ser Gly Gly Leu Ala Leu Pro Tyr Phe Asn 
        195                 200                 205             


Gly Thr Gly Thr Val Gln Lys Gly Arg Pro Arg Lys Arg Lys Ser Pro 
    210                 215                 220                 


Ala Leu Gly Val Asp Ile Val Asn Tyr Asn Ser Gly Cys Asn Glu Asn 
225                 230                 235                 240 


Glu Ala Asp His Leu Asp Arg Asp Gln Gln Pro Tyr Pro Pro Ser Gln 
                245                 250                 255     


Lys Thr Lys Arg Met Arg Thr Ser Phe Lys His His Gln Leu Arg Thr 
            260                 265                 270         


Met Lys Ser Tyr Phe Ala Ile Asn His Asn Pro Asp Ala Lys Asp Leu 
        275                 280                 285             


Lys Gln Leu Ala Gln Lys Thr Gly Leu Thr Lys Arg Val Leu Gln Val 
    290                 295                 300                 


Trp Phe Gln Asn Ala Arg Ala Lys Phe Arg Arg Asn Leu Leu Arg Gln 
305                 310                 315                 320 


Glu Asn Gly Gly Val Asp Lys Ala Asp Gly Thr Ser Leu Pro Ala Pro 
                325                 330                 335     


Pro Ser Ala Asp Ser Gly Ala Leu Thr Pro Pro Gly Thr Ala Thr Thr 
            340                 345                 350         


Leu Thr Asp Leu Thr Asn Pro Thr Ile Thr Val Val Thr Ser Val Thr 
        355                 360                 365             


Ser Asn Met Asp Ser His Glu Ser Gly Ser Pro Ser Gln Thr Thr Leu 
    370                 375                 380                 


Thr Asn Leu Phe 
385             


<210>  3339
<211>  183
<212>  PRT
<213>  homo sapiens

<400>  3339

Met Arg Ala Ala Tyr Leu Phe Leu Leu Phe Leu Pro Ala Gly Leu Leu 
1               5                   10                  15      


Ala Gln Gly Gln Tyr Asp Leu Asp Pro Leu Pro Pro Phe Pro Asp His 
            20                  25                  30          


Val Gln Tyr Thr His Tyr Ser Asp Gln Ile Asp Asn Pro Asp Tyr Tyr 
        35                  40                  45              


Asp Tyr Gln Glu Val Thr Pro Arg Pro Ser Glu Glu Gln Phe Gln Phe 
    50                  55                  60                  


Gln Ser Gln Gln Gln Val Gln Gln Glu Val Ile Pro Ala Pro Thr Pro 
65                  70                  75                  80  


Glu Pro Gly Asn Ala Glu Leu Glu Pro Thr Glu Pro Gly Pro Leu Asp 
                85                  90                  95      


Cys Arg Glu Glu Gln Tyr Pro Cys Thr Arg Leu Tyr Ser Ile His Arg 
            100                 105                 110         


Pro Cys Lys Gln Cys Leu Asn Glu Val Cys Phe Tyr Ser Leu Arg Arg 
        115                 120                 125             


Val Tyr Val Ile Asn Lys Glu Ile Cys Val Arg Thr Val Cys Ala His 
    130                 135                 140                 


Glu Glu Leu Leu Arg Ala Asp Leu Cys Arg Asp Lys Phe Ser Lys Cys 
145                 150                 155                 160 


Gly Val Met Ala Ser Ser Gly Leu Cys Gln Ser Val Ala Ala Ser Cys 
                165                 170                 175     


Ala Arg Ser Cys Gly Ser Cys 
            180             


<210>  3340
<211>  486
<212>  PRT
<213>  homo sapiens

<400>  3340

Met Val Ala Gly Met Leu Gly Leu Arg Glu Glu Lys Ser Glu Asp Gln 
1               5                   10                  15      


Asp Leu Gln Gly Leu Lys Asp Lys Pro Leu Lys Phe Lys Lys Val Lys 
            20                  25                  30          


Lys Asp Lys Lys Glu Glu Lys Glu Gly Lys His Glu Pro Val Gln Pro 
        35                  40                  45              


Ser Ala His His Ser Ala Glu Pro Ala Glu Ala Gly Lys Ala Glu Thr 
    50                  55                  60                  


Ser Glu Gly Ser Gly Ser Ala Pro Ala Val Pro Glu Ala Ser Ala Ser 
65                  70                  75                  80  


Pro Lys Gln Arg Arg Ser Ile Ile Arg Asp Arg Gly Pro Met Tyr Asp 
                85                  90                  95      


Asp Pro Thr Leu Pro Glu Gly Trp Thr Arg Lys Leu Lys Gln Arg Lys 
            100                 105                 110         


Ser Gly Arg Ser Ala Gly Lys Tyr Asp Val Tyr Leu Ile Asn Pro Gln 
        115                 120                 125             


Gly Lys Ala Phe Arg Ser Lys Val Glu Leu Ile Ala Tyr Phe Glu Lys 
    130                 135                 140                 


Val Gly Asp Thr Ser Leu Asp Pro Asn Asp Phe Asp Phe Thr Val Thr 
145                 150                 155                 160 


Gly Arg Gly Ser Pro Ser Arg Arg Glu Gln Lys Pro Pro Lys Lys Pro 
                165                 170                 175     


Lys Ser Pro Lys Ala Pro Gly Thr Gly Arg Gly Arg Gly Arg Pro Lys 
            180                 185                 190         


Gly Ser Gly Thr Thr Arg Pro Lys Ala Ala Thr Ser Glu Gly Val Gln 
        195                 200                 205             


Val Lys Arg Val Leu Glu Lys Ser Pro Gly Lys Leu Leu Val Lys Met 
    210                 215                 220                 


Pro Phe Gln Thr Ser Pro Gly Gly Lys Ala Glu Gly Gly Gly Ala Thr 
225                 230                 235                 240 


Thr Ser Thr Gln Val Met Val Ile Lys Arg Pro Gly Arg Lys Arg Lys 
                245                 250                 255     


Ala Glu Ala Asp Pro Gln Ala Ile Pro Lys Lys Arg Gly Arg Lys Pro 
            260                 265                 270         


Gly Ser Val Val Ala Ala Ala Ala Ala Glu Ala Lys Lys Lys Ala Val 
        275                 280                 285             


Lys Glu Ser Ser Ile Arg Ser Val Gln Glu Thr Val Leu Pro Ile Lys 
    290                 295                 300                 


Lys Arg Lys Thr Arg Glu Thr Val Ser Ile Glu Val Lys Glu Val Val 
305                 310                 315                 320 


Lys Pro Leu Leu Val Ser Thr Leu Gly Glu Lys Ser Gly Lys Gly Leu 
                325                 330                 335     


Lys Thr Cys Lys Ser Pro Gly Arg Lys Ser Lys Glu Ser Ser Pro Lys 
            340                 345                 350         


Gly Arg Ser Ser Ser Ala Ser Ser Pro Pro Lys Lys Glu His His His 
        355                 360                 365             


His His His His Ser Glu Ser Pro Lys Ala Pro Val Pro Leu Leu Pro 
    370                 375                 380                 


Pro Leu Pro Pro Pro Pro Pro Glu Pro Glu Ser Ser Glu Asp Pro Thr 
385                 390                 395                 400 


Ser Pro Pro Glu Pro Gln Asp Leu Ser Ser Ser Val Cys Lys Glu Glu 
                405                 410                 415     


Lys Met Pro Arg Gly Gly Ser Leu Glu Ser Asp Gly Cys Pro Lys Glu 
            420                 425                 430         


Pro Ala Lys Thr Gln Pro Ala Val Ala Thr Ala Ala Thr Ala Ala Glu 
        435                 440                 445             


Lys Tyr Lys His Arg Gly Glu Gly Glu Arg Lys Asp Ile Val Ser Ser 
    450                 455                 460                 


Ser Met Pro Arg Pro Asn Arg Glu Glu Pro Val Asp Ser Arg Thr Pro 
465                 470                 475                 480 


Val Thr Glu Arg Val Ser 
                485     


<210>  3341
<211>  175
<212>  PRT
<213>  homo sapiens

<400>  3341

Met Ala Gln Ser Gln Gly Trp Val Lys Arg Tyr Ile Lys Ala Phe Cys 
1               5                   10                  15      


Lys Gly Phe Phe Val Ala Val Pro Val Ala Val Thr Phe Leu Asp Arg 
            20                  25                  30          


Val Ala Cys Val Ala Arg Val Glu Gly Ala Ser Met Gln Pro Ser Leu 
        35                  40                  45              


Asn Pro Gly Gly Ser Gln Ser Ser Asp Val Val Leu Leu Asn His Trp 
    50                  55                  60                  


Lys Val Arg Asn Phe Glu Val His Arg Gly Asp Ile Val Ser Leu Val 
65                  70                  75                  80  


Ser Pro Lys Asn Pro Glu Gln Lys Ile Ile Lys Arg Val Ile Ala Leu 
                85                  90                  95      


Glu Gly Asp Ile Val Arg Thr Ile Gly His Lys Asn Arg Tyr Val Lys 
            100                 105                 110         


Val Pro Arg Gly His Ile Trp Val Glu Gly Asp His His Gly His Ser 
        115                 120                 125             


Phe Asp Ser Asn Ser Phe Gly Pro Val Ser Leu Gly Leu Leu His Ala 
    130                 135                 140                 


His Ala Thr His Ile Leu Trp Pro Pro Glu Arg Trp Gln Lys Leu Glu 
145                 150                 155                 160 


Ser Val Leu Pro Pro Glu Arg Leu Pro Val Gln Arg Glu Glu Glu 
                165                 170                 175 


<210>  3342
<211>  819
<212>  PRT
<213>  homo sapiens

<400>  3342

Met Ala Ala Pro Ala Gly Lys Ala Ser Arg Thr Gly Ala Leu Arg Pro 
1               5                   10                  15      


Arg Ala Gln Lys Gly Arg Val Arg Arg Ala Val Arg Ile Ser Ser Leu 
            20                  25                  30          


Val Ala Gln Glu Val Leu Ser Leu Gly Ala Asp Val Leu Pro Glu Tyr 
        35                  40                  45              


Lys Leu Gln Ala Pro Arg Ile His Arg Trp Thr Ile Leu His Tyr Ser 
    50                  55                  60                  


Pro Phe Lys Ala Val Trp Asp Trp Leu Ile Leu Leu Leu Val Ile Tyr 
65                  70                  75                  80  


Thr Ala Val Phe Thr Pro Tyr Ser Ala Ala Phe Leu Leu Lys Glu Thr 
                85                  90                  95      


Glu Glu Gly Pro Pro Ala Thr Glu Cys Gly Tyr Ala Cys Gln Pro Leu 
            100                 105                 110         


Ala Val Val Asp Leu Ile Val Asp Ile Met Phe Ile Val Asp Ile Leu 
        115                 120                 125             


Ile Asn Phe Arg Thr Thr Tyr Val Asn Ala Asn Glu Glu Val Val Ser 
    130                 135                 140                 


His Pro Gly Arg Ile Ala Val His Tyr Phe Lys Gly Trp Phe Leu Ile 
145                 150                 155                 160 


Asp Met Val Ala Ala Ile Pro Phe Asp Leu Leu Ile Phe Gly Ser Gly 
                165                 170                 175     


Ser Glu Glu Leu Ile Gly Leu Leu Lys Thr Ala Arg Leu Leu Arg Leu 
            180                 185                 190         


Val Arg Val Ala Arg Lys Leu Asp Arg Tyr Ser Glu Tyr Gly Ala Ala 
        195                 200                 205             


Val Leu Phe Leu Leu Met Cys Thr Phe Ala Leu Ile Ala His Trp Leu 
    210                 215                 220                 


Ala Cys Ile Trp Tyr Ala Ile Gly Asn Met Glu Gln Pro His Met Asp 
225                 230                 235                 240 


Ser Arg Ile Gly Trp Leu His Asn Leu Gly Asp Gln Ile Gly Lys Pro 
                245                 250                 255     


Tyr Asn Ser Ser Gly Leu Gly Gly Pro Ser Ile Lys Asp Lys Tyr Val 
            260                 265                 270         


Thr Ala Leu Tyr Phe Thr Phe Ser Ser Leu Thr Ser Val Gly Phe Gly 
        275                 280                 285             


Asn Val Ser Pro Asn Thr Asn Ser Glu Lys Ile Phe Ser Ile Cys Val 
    290                 295                 300                 


Met Leu Ile Gly Ser Leu Met Tyr Ala Ser Ile Phe Gly Asn Val Ser 
305                 310                 315                 320 


Ala Ile Ile Gln Arg Leu Tyr Ser Gly Thr Ala Arg Tyr His Thr Gln 
                325                 330                 335     


Met Leu Arg Val Arg Glu Phe Ile Arg Phe His Gln Ile Pro Asn Pro 
            340                 345                 350         


Leu Arg Gln Arg Leu Glu Glu Tyr Phe Gln His Ala Trp Ser Tyr Thr 
        355                 360                 365             


Asn Gly Ile Asp Met Asn Ala Val Leu Lys Gly Phe Pro Glu Cys Leu 
    370                 375                 380                 


Gln Ala Asp Ile Cys Leu His Leu Asn Arg Ser Leu Leu Gln His Cys 
385                 390                 395                 400 


Lys Pro Phe Arg Gly Ala Thr Lys Gly Cys Leu Arg Ala Leu Ala Met 
                405                 410                 415     


Lys Phe Lys Thr Thr His Ala Pro Pro Gly Asp Thr Leu Val His Ala 
            420                 425                 430         


Gly Asp Leu Leu Thr Ala Leu Tyr Phe Ile Ser Arg Gly Ser Ile Glu 
        435                 440                 445             


Ile Leu Arg Gly Asp Val Val Val Ala Ile Leu Gly Lys Asn Asp Ile 
    450                 455                 460                 


Phe Gly Glu Pro Leu Asn Leu Tyr Ala Arg Pro Gly Lys Ser Asn Gly 
465                 470                 475                 480 


Asp Val Arg Ala Leu Thr Tyr Cys Asp Leu His Lys Ile His Arg Asp 
                485                 490                 495     


Asp Leu Leu Glu Val Leu Asp Met Tyr Pro Glu Phe Ser Asp His Phe 
            500                 505                 510         


Trp Ser Ser Leu Glu Ile Thr Phe Asn Leu Arg Asp Thr Asn Met Ile 
        515                 520                 525             


Pro Gly Ser Pro Gly Ser Thr Glu Leu Glu Gly Gly Phe Ser Arg Gln 
    530                 535                 540                 


Arg Lys Arg Lys Leu Ser Phe Arg Arg Arg Thr Asp Lys Asp Thr Glu 
545                 550                 555                 560 


Gln Pro Gly Glu Val Ser Ala Leu Gly Pro Gly Arg Ala Gly Ala Gly 
                565                 570                 575     


Pro Ser Ser Arg Gly Arg Pro Gly Gly Pro Trp Gly Glu Ser Pro Ser 
            580                 585                 590         


Ser Gly Pro Ser Ser Pro Glu Ser Ser Glu Asp Glu Gly Pro Gly Arg 
        595                 600                 605             


Ser Ser Ser Pro Leu Arg Leu Val Pro Phe Ser Ser Pro Arg Pro Pro 
    610                 615                 620                 


Gly Glu Pro Pro Gly Gly Glu Pro Leu Met Glu Asp Cys Glu Lys Ser 
625                 630                 635                 640 


Ser Asp Thr Cys Asn Pro Leu Ser Gly Ala Phe Ser Gly Val Ser Asn 
                645                 650                 655     


Ile Phe Ser Phe Trp Gly Asp Ser Arg Gly Arg Gln Tyr Gln Glu Leu 
            660                 665                 670         


Pro Arg Cys Pro Ala Pro Thr Pro Ser Leu Leu Asn Ile Pro Leu Ser 
        675                 680                 685             


Ser Pro Gly Arg Arg Pro Arg Gly Asp Val Glu Ser Arg Leu Asp Ala 
    690                 695                 700                 


Leu Gln Arg Gln Leu Asn Arg Leu Glu Thr Arg Leu Ser Ala Asp Met 
705                 710                 715                 720 


Ala Thr Val Leu Gln Leu Leu Gln Arg Gln Met Thr Leu Val Pro Pro 
                725                 730                 735     


Ala Tyr Ser Ala Val Thr Thr Pro Gly Pro Gly Pro Thr Ser Thr Ser 
            740                 745                 750         


Pro Leu Leu Pro Val Ser Pro Leu Pro Thr Leu Thr Leu Asp Ser Leu 
        755                 760                 765             


Ser Gln Val Ser Gln Phe Met Ala Cys Glu Glu Leu Pro Pro Gly Ala 
    770                 775                 780                 


Pro Glu Leu Pro Gln Glu Gly Pro Thr Arg Arg Leu Ser Leu Pro Gly 
785                 790                 795                 800 


Gln Leu Gly Ala Leu Thr Ser Gln Pro Leu His Arg His Gly Ser Asp 
                805                 810                 815     


Pro Gly Ser 
            


<210>  3343
<211>  512
<212>  PRT
<213>  homo sapiens

<400>  3343

Met Tyr Cys Ala Tyr Pro Val Pro Gly Met Gly Ser Asn Ser Leu Met 
1               5                   10                  15      


Tyr Tyr Tyr Asn Gly Lys Thr Val Tyr Ala Pro Ser Pro Asn Ser Asp 
            20                  25                  30          


Asp Phe Asn Arg Glu Ser Pro Ser Tyr Pro Ser Pro Lys Pro Pro Thr 
        35                  40                  45              


Ser Met Phe Ala Ser Thr Phe Phe Met Gln Asp Gly Thr His Asn Ser 
    50                  55                  60                  


Ser Asp Leu Trp Ser Ser Ser Asn Gly Met Ser Gln Pro Gly Phe Gly 
65                  70                  75                  80  


Gly Ile Leu Gly Thr Ser Thr Ser His Met Ser Gln Ser Ser Ser Tyr 
                85                  90                  95      


Gly Asn Leu His Ser His Asp Arg Leu Ser Tyr Pro Pro His Ser Val 
            100                 105                 110         


Ser Pro Thr Asp Ile Asn Thr Ser Leu Pro Pro Met Ser Ser Phe His 
        115                 120                 125             


Arg Gly Ser Thr Ser Ser Ser Pro Tyr Val Ala Ala Ser His Thr Pro 
    130                 135                 140                 


Pro Ile Asn Gly Ser Asp Ser Ile Leu Gly Thr Arg Gly Asn Ala Ala 
145                 150                 155                 160 


Gly Ser Ser Gln Thr Gly Asp Ala Leu Gly Lys Ala Leu Ala Ser Ile 
                165                 170                 175     


Tyr Ser Pro Asp His Thr Ser Ser Ser Phe Pro Ser Asn Pro Ser Thr 
            180                 185                 190         


Pro Val Gly Ser Pro Ser Pro Leu Thr Gly Thr Ser Gln Trp Pro Arg 
        195                 200                 205             


Pro Gly Gly Gln Ala Pro Ser Ser Pro Ser Tyr Glu Asn Ser Leu His 
    210                 215                 220                 


Ser Leu Gln Ser Arg Met Glu Asp Arg Leu Asp Arg Leu Asp Asp Ala 
225                 230                 235                 240 


Ile His Val Leu Arg Asn His Ala Val Gly Pro Ser Thr Ser Leu Pro 
                245                 250                 255     


Ala Gly His Ser Asp Ile His Ser Leu Leu Gly Pro Ser His Asn Ala 
            260                 265                 270         


Pro Ile Gly Ser Leu Asn Ser Asn Tyr Gly Gly Ser Ser Leu Val Ala 
        275                 280                 285             


Ser Ser Arg Ser Ala Ser Met Val Gly Thr His Arg Glu Asp Ser Val 
    290                 295                 300                 


Ser Leu Asn Gly Asn His Ser Val Leu Ser Ser Thr Val Thr Thr Ser 
305                 310                 315                 320 


Ser Thr Asp Leu Asn His Lys Thr Gln Glu Asn Tyr Arg Gly Gly Leu 
                325                 330                 335     


Gln Ser Gln Ser Gly Thr Val Val Thr Thr Glu Ile Lys Thr Glu Asn 
            340                 345                 350         


Lys Glu Lys Asp Glu Asn Leu His Glu Pro Pro Ser Ser Asp Asp Met 
        355                 360                 365             


Lys Ser Asp Asp Glu Ser Ser Gln Lys Asp Ile Lys Val Ser Ser Arg 
    370                 375                 380                 


Gly Arg Thr Ser Ser Thr Asn Glu Asp Glu Asp Leu Asn Pro Glu Gln 
385                 390                 395                 400 


Lys Ile Glu Arg Glu Lys Glu Arg Arg Met Ala Asn Asn Ala Arg Glu 
                405                 410                 415     


Arg Leu Arg Val Arg Asp Ile Asn Glu Ala Phe Lys Glu Leu Gly Arg 
            420                 425                 430         


Met Cys Gln Leu His Leu Lys Ser Glu Lys Pro Gln Thr Lys Leu Leu 
        435                 440                 445             


Ile Leu His Gln Ala Val Ala Val Ile Leu Ser Leu Glu Gln Gln Val 
    450                 455                 460                 


Arg Glu Arg Asn Leu Asn Pro Lys Ala Ala Cys Leu Lys Arg Arg Glu 
465                 470                 475                 480 


Glu Glu Lys Val Ser Ala Val Ser Ala Glu Pro Pro Thr Thr Leu Pro 
                485                 490                 495     


Gly Thr His Pro Gly Leu Ser Glu Thr Thr Asn Pro Met Gly His Met 
            500                 505                 510         


<210>  3344
<211>  408
<212>  PRT
<213>  homo sapiens

<400>  3344

Met Ile Pro Gly Asn Arg Met Leu Met Val Val Leu Leu Cys Gln Val 
1               5                   10                  15      


Leu Leu Gly Gly Ala Ser His Ala Ser Leu Ile Pro Glu Thr Gly Lys 
            20                  25                  30          


Lys Lys Val Ala Glu Ile Gln Gly His Ala Gly Gly Arg Arg Ser Gly 
        35                  40                  45              


Gln Ser His Glu Leu Leu Arg Asp Phe Glu Ala Thr Leu Leu Gln Met 
    50                  55                  60                  


Phe Gly Leu Arg Arg Arg Pro Gln Pro Ser Lys Ser Ala Val Ile Pro 
65                  70                  75                  80  


Asp Tyr Met Arg Asp Leu Tyr Arg Leu Gln Ser Gly Glu Glu Glu Glu 
                85                  90                  95      


Glu Gln Ile His Ser Thr Gly Leu Glu Tyr Pro Glu Arg Pro Ala Ser 
            100                 105                 110         


Arg Ala Asn Thr Val Arg Ser Phe His His Glu Glu His Leu Glu Asn 
        115                 120                 125             


Ile Pro Gly Thr Ser Glu Asn Ser Ala Phe Arg Phe Leu Phe Asn Leu 
    130                 135                 140                 


Ser Ser Ile Pro Glu Asn Glu Val Ile Ser Ser Ala Glu Leu Arg Leu 
145                 150                 155                 160 


Phe Arg Glu Gln Val Asp Gln Gly Pro Asp Trp Glu Arg Gly Phe His 
                165                 170                 175     


Arg Ile Asn Ile Tyr Glu Val Met Lys Pro Pro Ala Glu Val Val Pro 
            180                 185                 190         


Gly His Leu Ile Thr Arg Leu Leu Asp Thr Arg Leu Val His His Asn 
        195                 200                 205             


Val Thr Arg Trp Glu Thr Phe Asp Val Ser Pro Ala Val Leu Arg Trp 
    210                 215                 220                 


Thr Arg Glu Lys Gln Pro Asn Tyr Gly Leu Ala Ile Glu Val Thr His 
225                 230                 235                 240 


Leu His Gln Thr Arg Thr His Gln Gly Gln His Val Arg Ile Ser Arg 
                245                 250                 255     


Ser Leu Pro Gln Gly Ser Gly Asn Trp Ala Gln Leu Arg Pro Leu Leu 
            260                 265                 270         


Val Thr Phe Gly His Asp Gly Arg Gly His Ala Leu Thr Arg Arg Arg 
        275                 280                 285             


Arg Ala Lys Arg Ser Pro Lys His His Ser Gln Arg Ala Arg Lys Lys 
    290                 295                 300                 


Asn Lys Asn Cys Arg Arg His Ser Leu Tyr Val Asp Phe Ser Asp Val 
305                 310                 315                 320 


Gly Trp Asn Asp Trp Ile Val Ala Pro Pro Gly Tyr Gln Ala Phe Tyr 
                325                 330                 335     


Cys His Gly Asp Cys Pro Phe Pro Leu Ala Asp His Leu Asn Ser Thr 
            340                 345                 350         


Asn His Ala Ile Val Gln Thr Leu Val Asn Ser Val Asn Ser Ser Ile 
        355                 360                 365             


Pro Lys Ala Cys Cys Val Pro Thr Glu Leu Ser Ala Ile Ser Met Leu 
    370                 375                 380                 


Tyr Leu Asp Glu Tyr Asp Lys Val Val Leu Lys Asn Tyr Gln Glu Met 
385                 390                 395                 400 


Val Val Glu Gly Cys Gly Cys Arg 
                405             


<210>  3345
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  3345

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Met Gln Asp Leu 
1               5                   10                  15      


Leu Glu Ser Thr Asp Phe Thr Glu His Glu Ile Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Arg Asp Cys Pro Ser Gly His Leu Ser Met Glu Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Gly Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Ala Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Lys Ala Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Glu Lys Ile Phe Arg Gln Met Asp Thr Asn Arg 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Gly Gln 
            180                 185                 190         


Phe 
    


<210>  3346
<211>  345
<212>  PRT
<213>  homo sapiens

<400>  3346

Met Gln Leu Glu Ile Gln Val Ala Leu Asn Phe Ile Ile Ser Tyr Leu 
1               5                   10                  15      


Tyr Asn Lys Leu Pro Arg Arg Arg Val Asn Ile Phe Gly Glu Glu Leu 
            20                  25                  30          


Glu Arg Leu Leu Lys Lys Lys Tyr Glu Gly His Trp Tyr Pro Glu Lys 
        35                  40                  45              


Pro Tyr Lys Gly Ser Gly Phe Arg Cys Ile His Ile Gly Glu Lys Val 
    50                  55                  60                  


Asp Pro Val Ile Glu Gln Ala Ser Lys Glu Ser Gly Leu Asp Ile Asp 
65                  70                  75                  80  


Asp Val Arg Gly Asn Leu Pro Gln Asp Leu Ser Val Trp Ile Asp Pro 
                85                  90                  95      


Phe Glu Val Ser Tyr Gln Ile Gly Glu Lys Gly Pro Val Lys Val Leu 
            100                 105                 110         


Tyr Val Asp Asp Asn Asn Glu Asn Gly Cys Glu Leu Asp Lys Glu Ile 
        115                 120                 125             


Lys Asn Ser Phe Asn Pro Glu Ala Gln Val Phe Met Pro Ile Ser Asp 
    130                 135                 140                 


Pro Ala Ser Ser Val Ser Ser Ser Pro Ser Pro Pro Phe Gly His Ser 
145                 150                 155                 160 


Ala Ala Val Ser Pro Thr Phe Met Pro Arg Ser Thr Gln Pro Leu Thr 
                165                 170                 175     


Phe Thr Thr Ala Thr Phe Ala Ala Thr Lys Phe Gly Ser Thr Lys Met 
            180                 185                 190         


Lys Asn Ser Gly Arg Ser Asn Lys Val Ala Arg Thr Ser Pro Ile Asn 
        195                 200                 205             


Leu Gly Leu Asn Val Asn Asp Leu Leu Lys Gln Lys Ala Ile Ser Ser 
    210                 215                 220                 


Ser Met His Ser Leu Tyr Gly Leu Gly Leu Gly Ser Gln Gln Gln Pro 
225                 230                 235                 240 


Gln Gln Gln Gln Gln Pro Ala Gln Pro Pro Pro Pro Pro Pro Pro Pro 
                245                 250                 255     


Gln Gln Gln Gln Gln Gln Lys Thr Ser Ala Leu Ser Pro Asn Ala Lys 
            260                 265                 270         


Glu Phe Ile Phe Pro Asn Met Gln Gly Gln Gly Ser Ser Thr Asn Gly 
        275                 280                 285             


Met Phe Pro Gly Asp Ser Pro Leu Asn Leu Ser Pro Leu Gln Tyr Ser 
    290                 295                 300                 


Asn Ala Phe Asp Val Phe Ala Ala Tyr Gly Gly Leu Asn Glu Lys Ser 
305                 310                 315                 320 


Phe Val Asp Gly Leu Asn Phe Ser Leu Asn Asn Met Gln Tyr Ser Asn 
                325                 330                 335     


Gln Gln Phe Gln Pro Val Met Ala Asn 
            340                 345 


<210>  3347
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  3347

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Met Gln Asp Leu 
1               5                   10                  15      


Leu Glu Ser Thr Asp Phe Thr Glu His Glu Ile Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Arg Asp Cys Pro Ser Gly His Leu Ser Met Glu Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Gly Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Ala Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Lys Ala Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Glu Lys Ile Phe Arg Gln Met Asp Thr Asn Arg 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Gly Gln 
            180                 185                 190         


Phe 
    


<210>  3348
<211>  498
<212>  PRT
<213>  homo sapiens

<400>  3348

Met Tyr Ser Pro Leu Cys Leu Thr Gln Asp Glu Phe His Pro Phe Ile 
1               5                   10                  15      


Glu Ala Leu Leu Pro His Val Arg Ala Phe Ala Tyr Thr Trp Phe Asn 
            20                  25                  30          


Leu Gln Ala Arg Lys Arg Lys Tyr Phe Lys Lys His Glu Lys Arg Met 
        35                  40                  45              


Ser Lys Glu Glu Glu Arg Ala Val Lys Asp Glu Leu Leu Ser Glu Lys 
    50                  55                  60                  


Pro Glu Val Lys Gln Lys Trp Ala Ser Arg Leu Leu Ala Lys Leu Arg 
65                  70                  75                  80  


Lys Asp Ile Arg Pro Glu Tyr Arg Glu Asp Phe Val Leu Thr Val Thr 
                85                  90                  95      


Gly Lys Lys Pro Pro Cys Cys Val Leu Ser Asn Pro Asp Gln Lys Gly 
            100                 105                 110         


Lys Met Arg Arg Ile Asp Cys Leu Arg Gln Ala Asp Lys Val Trp Arg 
        115                 120                 125             


Leu Asp Leu Val Met Val Ile Leu Phe Lys Gly Ile Pro Leu Glu Ser 
    130                 135                 140                 


Thr Asp Gly Glu Arg Leu Val Lys Ser Pro Gln Cys Ser Asn Pro Gly 
145                 150                 155                 160 


Leu Cys Val Gln Pro His His Ile Gly Val Ser Val Lys Glu Leu Asp 
                165                 170                 175     


Leu Tyr Leu Ala Tyr Phe Val His Ala Ala Asp Ser Ser Gln Ser Glu 
            180                 185                 190         


Ser Pro Ser Gln Pro Ser Asp Ala Asp Ile Lys Asp Gln Pro Glu Asn 
        195                 200                 205             


Gly His Leu Gly Phe Gln Asp Ser Phe Val Thr Ser Gly Val Phe Ser 
    210                 215                 220                 


Val Thr Glu Leu Val Arg Val Ser Gln Thr Pro Ile Ala Ala Gly Thr 
225                 230                 235                 240 


Gly Pro Asn Phe Ser Leu Ser Asp Leu Glu Ser Ser Ser Tyr Tyr Ser 
                245                 250                 255     


Met Ser Pro Gly Ala Met Arg Arg Ser Leu Pro Ser Thr Ser Ser Thr 
            260                 265                 270         


Ser Ser Thr Lys Arg Leu Lys Ser Val Glu Asp Glu Met Asp Ser Pro 
        275                 280                 285             


Gly Glu Glu Pro Phe Tyr Thr Gly Gln Gly Arg Ser Pro Gly Ser Gly 
    290                 295                 300                 


Ser Gln Ser Ser Gly Trp His Glu Val Glu Pro Gly Met Pro Ser Pro 
305                 310                 315                 320 


Thr Thr Leu Lys Lys Ser Glu Lys Ser Gly Phe Ser Ser Pro Ser Pro 
                325                 330                 335     


Ser Gln Thr Ser Ser Leu Gly Thr Ala Phe Thr Gln His His Arg Pro 
            340                 345                 350         


Val Ile Thr Gly Pro Arg Ala Ser Pro His Ala Thr Pro Ser Thr Leu 
        355                 360                 365             


His Phe Pro Thr Ser Pro Ile Ile Gln Gln Pro Gly Pro Tyr Phe Ser 
    370                 375                 380                 


His Pro Ala Ile Arg Tyr His Pro Gln Glu Thr Leu Lys Glu Phe Val 
385                 390                 395                 400 


Gln Leu Val Cys Pro Asp Ala Gly Gln Gln Ala Gly Gln Val Gly Phe 
                405                 410                 415     


Leu Asn Pro Asn Gly Ser Ser Gln Gly Lys Val His Asn Pro Phe Leu 
            420                 425                 430         


Pro Thr Pro Met Leu Pro Pro Pro Pro Pro Pro Pro Met Ala Arg Pro 
        435                 440                 445             


Val Pro Leu Pro Val Pro Asp Thr Lys Pro Pro Thr Thr Ser Thr Glu 
    450                 455                 460                 


Gly Gly Ala Ala Ser Pro Thr Ser Pro Ile Leu Val Pro Gly Ile Lys 
465                 470                 475                 480 


Val Ala Ala Ser His His Pro Pro Asp Arg Pro Pro Asp Pro Phe Ser 
                485                 490                 495     


Thr Leu 
        


<210>  3349
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  3349

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Met Gln Asp Leu 
1               5                   10                  15      


Leu Glu Ser Thr Asp Phe Thr Glu His Glu Ile Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Arg Asp Cys Pro Ser Gly His Leu Ser Met Glu Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Gly Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Ala Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Lys Ala Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Glu Lys Ile Phe Arg Gln Met Asp Thr Asn Arg 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Gly Gln 
            180                 185                 190         


Phe 
    


<210>  3350
<211>  370
<212>  PRT
<213>  homo sapiens

<400>  3350

Met Asp Ala Pro Arg Gln Val Val Asn Phe Gly Pro Gly Pro Ala Lys 
1               5                   10                  15      


Leu Pro His Ser Val Leu Leu Glu Ile Gln Lys Glu Leu Leu Asp Tyr 
            20                  25                  30          


Lys Gly Val Gly Ile Ser Val Leu Glu Met Ser His Arg Ser Ser Asp 
        35                  40                  45              


Phe Ala Lys Ile Ile Asn Asn Thr Glu Asn Leu Val Arg Glu Leu Leu 
    50                  55                  60                  


Ala Val Pro Asp Asn Tyr Lys Val Ile Phe Leu Gln Gly Gly Gly Cys 
65                  70                  75                  80  


Gly Gln Phe Ser Ala Val Pro Leu Asn Leu Ile Gly Leu Lys Ala Gly 
                85                  90                  95      


Arg Cys Ala Asp Tyr Val Val Thr Gly Ala Trp Ser Ala Lys Ala Ala 
            100                 105                 110         


Glu Glu Ala Lys Lys Phe Gly Thr Ile Asn Ile Val His Pro Lys Leu 
        115                 120                 125             


Gly Ser Tyr Thr Lys Ile Pro Asp Pro Ser Thr Trp Asn Leu Asn Pro 
    130                 135                 140                 


Asp Ala Ser Tyr Val Tyr Tyr Cys Ala Asn Glu Thr Val His Gly Val 
145                 150                 155                 160 


Glu Phe Asp Phe Ile Pro Asp Val Lys Gly Ala Val Leu Val Cys Asp 
                165                 170                 175     


Met Ser Ser Asn Phe Leu Ser Lys Pro Val Asp Val Ser Lys Phe Gly 
            180                 185                 190         


Val Ile Phe Ala Gly Ala Gln Lys Asn Val Gly Ser Ala Gly Val Thr 
        195                 200                 205             


Val Val Ile Val Arg Asp Asp Leu Leu Gly Phe Ala Leu Arg Glu Cys 
    210                 215                 220                 


Pro Ser Val Leu Glu Tyr Lys Val Gln Ala Gly Asn Ser Ser Leu Tyr 
225                 230                 235                 240 


Asn Thr Pro Pro Cys Phe Ser Ile Tyr Val Met Gly Leu Val Leu Glu 
                245                 250                 255     


Trp Ile Lys Asn Asn Gly Gly Ala Ala Ala Met Glu Lys Leu Ser Ser 
            260                 265                 270         


Ile Lys Ser Gln Thr Ile Tyr Glu Ile Ile Asp Asn Ser Gln Gly Phe 
        275                 280                 285             


Tyr Val Cys Pro Val Glu Pro Gln Asn Arg Ser Lys Met Asn Ile Pro 
    290                 295                 300                 


Phe Arg Ile Gly Asn Ala Lys Gly Asp Asp Ala Leu Glu Lys Arg Phe 
305                 310                 315                 320 


Leu Asp Lys Ala Leu Glu Leu Asn Met Leu Ser Leu Lys Gly His Arg 
                325                 330                 335     


Ser Val Gly Gly Ile Arg Ala Ser Leu Tyr Asn Ala Val Thr Ile Glu 
            340                 345                 350         


Asp Val Gln Lys Leu Ala Ala Phe Met Lys Lys Phe Leu Glu Met His 
        355                 360                 365             


Gln Leu 
    370 


<210>  3351
<211>  953
<212>  PRT
<213>  homo sapiens

<400>  3351

Met Ile Thr Ser Ala Ala Gly Ile Ile Ser Leu Leu Asp Glu Asp Glu 
1               5                   10                  15      


Pro Gln Leu Lys Glu Phe Ala Leu His Lys Leu Asn Ala Val Val Asn 
            20                  25                  30          


Asp Phe Trp Ala Glu Ile Ser Glu Ser Val Asp Lys Ile Glu Val Leu 
        35                  40                  45              


Tyr Glu Asp Glu Gly Phe Arg Ser Arg Gln Phe Ala Ala Leu Val Ala 
    50                  55                  60                  


Ser Lys Val Phe Tyr His Leu Gly Ala Phe Glu Glu Ser Leu Asn Tyr 
65                  70                  75                  80  


Ala Leu Gly Ala Gly Asp Leu Phe Asn Val Asn Asp Asn Ser Glu Tyr 
                85                  90                  95      


Val Glu Thr Ile Ile Ala Lys Cys Ile Asp His Tyr Thr Lys Gln Cys 
            100                 105                 110         


Val Glu Asn Ala Asp Leu Pro Glu Gly Glu Lys Lys Pro Ile Asp Gln 
        115                 120                 125             


Arg Leu Glu Gly Ile Val Asn Lys Met Phe Gln Arg Cys Leu Asp Asp 
    130                 135                 140                 


His Lys Tyr Lys Gln Ala Ile Gly Ile Ala Leu Glu Thr Arg Arg Leu 
145                 150                 155                 160 


Asp Val Phe Glu Lys Thr Ile Leu Glu Ser Asn Asp Val Pro Gly Met 
                165                 170                 175     


Leu Ala Tyr Ser Leu Lys Leu Cys Met Ser Leu Met Gln Asn Lys Gln 
            180                 185                 190         


Phe Arg Asn Lys Val Leu Arg Val Leu Val Lys Ile Tyr Met Asn Leu 
        195                 200                 205             


Glu Lys Pro Asp Phe Ile Asn Val Cys Gln Cys Leu Ile Phe Leu Asp 
    210                 215                 220                 


Asp Pro Gln Ala Val Ser Asp Ile Leu Glu Lys Leu Val Lys Glu Asp 
225                 230                 235                 240 


Asn Leu Leu Met Ala Tyr Gln Ile Cys Phe Asp Leu Tyr Glu Ser Ala 
                245                 250                 255     


Ser Gln Gln Phe Leu Ser Ser Val Ile Gln Asn Leu Arg Thr Val Gly 
            260                 265                 270         


Thr Pro Ile Ala Ser Val Pro Gly Ser Thr Asn Thr Gly Thr Val Pro 
        275                 280                 285             


Gly Ser Glu Lys Asp Ser Asp Ser Met Glu Thr Glu Glu Lys Thr Ser 
    290                 295                 300                 


Ser Ala Phe Val Gly Lys Thr Pro Glu Ala Ser Pro Glu Pro Lys Asp 
305                 310                 315                 320 


Gln Thr Leu Lys Met Ile Lys Ile Leu Ser Gly Glu Met Ala Ile Glu 
                325                 330                 335     


Leu His Leu Gln Phe Leu Ile Arg Asn Asn Asn Thr Asp Leu Met Ile 
            340                 345                 350         


Leu Lys Asn Thr Lys Asp Ala Val Arg Asn Ser Val Cys His Thr Ala 
        355                 360                 365             


Thr Val Ile Ala Asn Ser Phe Met His Cys Gly Thr Thr Ser Asp Gln 
    370                 375                 380                 


Phe Leu Arg Asp Asn Leu Glu Trp Leu Ala Arg Ala Thr Asn Trp Ala 
385                 390                 395                 400 


Lys Phe Thr Ala Thr Ala Ser Leu Gly Val Ile His Lys Gly His Glu 
                405                 410                 415     


Lys Glu Ala Leu Gln Leu Met Ala Thr Tyr Leu Pro Lys Asp Thr Ser 
            420                 425                 430         


Pro Gly Ser Ala Tyr Gln Glu Gly Gly Gly Leu Tyr Ala Leu Gly Leu 
        435                 440                 445             


Ile His Ala Asn His Gly Gly Asp Ile Ile Asp Tyr Leu Leu Asn Gln 
    450                 455                 460                 


Leu Lys Asn Ala Ser Asn Asp Ile Val Arg His Gly Gly Ser Leu Gly 
465                 470                 475                 480 


Leu Gly Leu Ala Ala Met Gly Thr Ala Arg Gln Asp Val Tyr Asp Leu 
                485                 490                 495     


Leu Lys Thr Asn Leu Tyr Gln Asp Asp Ala Val Thr Gly Glu Ala Ala 
            500                 505                 510         


Gly Leu Ala Leu Gly Leu Val Met Leu Gly Ser Lys Asn Ala Gln Ala 
        515                 520                 525             


Ile Glu Asp Met Val Gly Tyr Ala Gln Glu Thr Gln His Glu Lys Ile 
    530                 535                 540                 


Leu Arg Gly Leu Ala Val Gly Ile Ala Leu Val Met Tyr Gly Arg Met 
545                 550                 555                 560 


Glu Glu Ala Asp Ala Leu Ile Glu Ser Leu Cys Arg Asp Lys Asp Pro 
                565                 570                 575     


Ile Leu Arg Arg Ser Gly Met Tyr Thr Val Ala Met Ala Tyr Cys Gly 
            580                 585                 590         


Ser Gly Asn Asn Lys Ala Ile Arg Arg Leu Leu His Val Ala Val Ser 
        595                 600                 605             


Asp Val Asn Asp Asp Val Arg Arg Ala Ala Val Glu Ser Leu Gly Phe 
    610                 615                 620                 


Ile Leu Phe Arg Thr Pro Glu Gln Cys Pro Ser Val Val Ser Leu Leu 
625                 630                 635                 640 


Ser Glu Ser Tyr Asn Pro His Val Arg Tyr Gly Ala Ala Met Ala Leu 
                645                 650                 655     


Gly Ile Cys Cys Ala Gly Thr Gly Asn Lys Glu Ala Ile Asn Leu Leu 
            660                 665                 670         


Glu Pro Met Thr Asn Asp Pro Val Asn Tyr Val Arg Gln Gly Ala Leu 
        675                 680                 685             


Ile Ala Ser Ala Leu Ile Met Ile Gln Gln Thr Glu Ile Thr Cys Pro 
    690                 695                 700                 


Lys Val Asn Gln Phe Arg Gln Leu Tyr Ser Lys Val Ile Asn Asp Lys 
705                 710                 715                 720 


His Asp Asp Val Met Ala Lys Phe Gly Ala Ile Leu Ala Gln Gly Ile 
                725                 730                 735     


Leu Asp Ala Gly Gly His Asn Val Thr Ile Ser Leu Gln Ser Arg Thr 
            740                 745                 750         


Gly His Thr His Met Pro Ser Val Val Gly Val Leu Val Phe Thr Gln 
        755                 760                 765             


Phe Trp Phe Trp Phe Pro Leu Ser His Phe Leu Ser Leu Ala Tyr Thr 
    770                 775                 780                 


Pro Thr Cys Val Ile Gly Leu Asn Lys Asp Leu Lys Met Pro Lys Val 
785                 790                 795                 800 


Gln Tyr Lys Ser Asn Cys Lys Pro Ser Thr Phe Ala Tyr Pro Ala Pro 
                805                 810                 815     


Leu Glu Val Pro Lys Glu Lys Glu Lys Glu Lys Val Ser Thr Ala Val 
            820                 825                 830         


Leu Ser Ile Thr Ala Lys Ala Lys Lys Lys Glu Lys Glu Lys Glu Lys 
        835                 840                 845             


Lys Glu Glu Glu Lys Met Glu Val Asp Glu Ala Glu Lys Lys Glu Glu 
    850                 855                 860                 


Lys Glu Lys Lys Lys Glu Pro Glu Pro Asn Phe Gln Leu Leu Asp Asn 
865                 870                 875                 880 


Pro Ala Arg Val Met Pro Ala Gln Leu Lys Val Leu Thr Met Pro Glu 
                885                 890                 895     


Thr Cys Arg Tyr Gln Pro Phe Lys Pro Leu Ser Ile Gly Gly Ile Ile 
            900                 905                 910         


Ile Leu Lys Asp Thr Ser Glu Asp Ile Glu Glu Leu Val Glu Pro Val 
        915                 920                 925             


Ala Ala His Gly Pro Lys Ile Glu Glu Glu Glu Gln Glu Pro Glu Pro 
    930                 935                 940                 


Pro Glu Pro Phe Glu Tyr Ile Asp Asp 
945                 950             


<210>  3352
<211>  619
<212>  PRT
<213>  homo sapiens

<400>  3352

Met Ala Ala Val Val Gln Gln Asn Asp Leu Val Phe Glu Phe Ala Ser 
1               5                   10                  15      


Asn Val Met Glu Asp Glu Arg Gln Leu Gly Asp Pro Ala Ile Phe Pro 
            20                  25                  30          


Ala Val Ile Val Glu His Val Pro Gly Ala Asp Ile Leu Asn Ser Tyr 
        35                  40                  45              


Ala Gly Leu Ala Cys Val Glu Glu Pro Asn Asp Met Ile Thr Glu Ser 
    50                  55                  60                  


Ser Leu Asp Val Ala Glu Glu Glu Ile Ile Asp Asp Asp Asp Asp Asp 
65                  70                  75                  80  


Ile Thr Leu Thr Val Glu Ala Ser Cys His Asp Gly Asp Glu Thr Ile 
                85                  90                  95      


Glu Thr Ile Glu Ala Ala Glu Ala Leu Leu Asn Met Asp Ser Pro Gly 
            100                 105                 110         


Pro Met Leu Asp Glu Lys Arg Ile Asn Asn Asn Ile Phe Ser Ser Pro 
        115                 120                 125             


Glu Asp Asp Met Val Val Ala Pro Val Thr His Val Ser Val Thr Leu 
    130                 135                 140                 


Asp Gly Ile Pro Glu Val Met Glu Thr Gln Gln Val Gln Glu Lys Tyr 
145                 150                 155                 160 


Ala Asp Ser Pro Gly Ala Ser Ser Pro Glu Gln Pro Lys Arg Lys Lys 
                165                 170                 175     


Gly Arg Lys Thr Lys Pro Pro Arg Pro Asp Ser Pro Ala Thr Thr Pro 
            180                 185                 190         


Asn Ile Ser Val Lys Lys Lys Asn Lys Asp Gly Lys Gly Asn Thr Ile 
        195                 200                 205             


Tyr Leu Trp Glu Phe Leu Leu Ala Leu Leu Gln Asp Lys Ala Thr Cys 
    210                 215                 220                 


Pro Lys Tyr Ile Lys Trp Thr Gln Arg Glu Lys Gly Ile Phe Lys Leu 
225                 230                 235                 240 


Val Asp Ser Lys Ala Val Ser Arg Leu Trp Gly Lys His Lys Asn Lys 
                245                 250                 255     


Pro Asp Met Asn Tyr Glu Thr Met Gly Arg Ala Leu Arg Tyr Tyr Tyr 
            260                 265                 270         


Gln Arg Gly Ile Leu Ala Lys Val Glu Gly Gln Arg Leu Val Tyr Gln 
        275                 280                 285             


Phe Lys Glu Met Pro Lys Asp Leu Ile Tyr Ile Asn Asp Glu Asp Pro 
    290                 295                 300                 


Ser Ser Ser Ile Glu Ser Ser Asp Pro Ser Leu Ser Ser Ser Ala Thr 
305                 310                 315                 320 


Ser Asn Arg Asn Gln Thr Ser Arg Ser Arg Val Ser Ser Ser Pro Gly 
                325                 330                 335     


Val Lys Gly Gly Ala Thr Thr Val Leu Lys Pro Gly Asn Ser Lys Ala 
            340                 345                 350         


Ala Lys Pro Lys Asp Pro Val Glu Val Ala Gln Pro Ser Glu Val Leu 
        355                 360                 365             


Arg Thr Val Gln Pro Thr Gln Ser Pro Tyr Pro Thr Gln Leu Phe Arg 
    370                 375                 380                 


Thr Val His Val Val Gln Pro Val Gln Ala Val Pro Glu Gly Glu Ala 
385                 390                 395                 400 


Ala Arg Thr Ser Thr Met Gln Asp Glu Thr Leu Asn Ser Ser Val Gln 
                405                 410                 415     


Ser Ile Arg Thr Ile Gln Ala Pro Thr Gln Val Pro Val Val Val Ser 
            420                 425                 430         


Pro Arg Asn Gln Gln Leu His Thr Val Thr Leu Gln Thr Val Pro Leu 
        435                 440                 445             


Thr Thr Val Ile Ala Ser Thr Asp Pro Ser Ala Gly Thr Gly Ser Gln 
    450                 455                 460                 


Lys Phe Ile Leu Gln Ala Ile Pro Ser Ser Gln Pro Met Thr Val Leu 
465                 470                 475                 480 


Lys Glu Asn Val Met Leu Gln Ser Gln Lys Ala Gly Ser Pro Pro Ser 
                485                 490                 495     


Ile Val Leu Gly Pro Ala Gln Val Gln Gln Val Leu Thr Ser Asn Val 
            500                 505                 510         


Gln Thr Ile Cys Asn Gly Thr Val Ser Val Ala Ser Ser Pro Ser Phe 
        515                 520                 525             


Ser Ala Thr Ala Pro Val Val Thr Phe Ser Pro Arg Ser Ser Gln Leu 
    530                 535                 540                 


Val Ala His Pro Pro Gly Thr Val Ile Thr Ser Val Ile Lys Thr Gln 
545                 550                 555                 560 


Glu Thr Lys Thr Leu Thr Gln Glu Val Glu Lys Lys Glu Ser Glu Asp 
                565                 570                 575     


His Leu Lys Glu Asn Thr Glu Lys Thr Glu Gln Gln Pro Gln Pro Tyr 
            580                 585                 590         


Val Met Val Val Ser Ser Ser Asn Gly Phe Thr Ser Gln Val Ala Met 
        595                 600                 605             


Lys Gln Asn Glu Leu Leu Glu Pro Asn Ser Phe 
    610                 615                 


<210>  3353
<211>  581
<212>  PRT
<213>  homo sapiens

<400>  3353

Met Thr Ser Ala Val Val Asp Ser Gly Gly Thr Ile Leu Glu Leu Ser 
1               5                   10                  15      


Ser Asn Gly Val Glu Asn Gln Glu Glu Ser Glu Lys Val Ser Glu Tyr 
            20                  25                  30          


Pro Ala Val Ile Val Glu Pro Val Pro Ser Ala Arg Leu Glu Gln Gly 
        35                  40                  45              


Tyr Ala Ala Gln Val Leu Val Tyr Asp Asp Glu Thr Tyr Met Met Gln 
    50                  55                  60                  


Asp Val Ala Glu Glu Gln Glu Val Glu Thr Glu Asn Val Glu Thr Val 
65                  70                  75                  80  


Glu Ala Ser Val His Ser Ser Asn Ala His Cys Thr Asp Lys Thr Ile 
                85                  90                  95      


Glu Ala Ala Glu Ala Leu Leu His Met Glu Ser Pro Thr Cys Leu Arg 
            100                 105                 110         


Asp Ser Arg Ser Pro Glu Phe Ile His Ala Ala Met Arg Pro Asp Val 
        115                 120                 125             


Ile Thr Glu Thr Val Val Glu Val Ser Thr Glu Glu Ser Glu Pro Met 
    130                 135                 140                 


Asp Thr Ser Pro Ile Pro Thr Ser Pro Asp Ser His Glu Pro Met Lys 
145                 150                 155                 160 


Lys Lys Lys Val Gly Arg Lys Pro Lys Thr Gln Gln Ser Pro Ile Ser 
                165                 170                 175     


Asn Gly Ser Pro Glu Leu Gly Ile Lys Lys Lys Pro Arg Glu Gly Lys 
            180                 185                 190         


Gly Asn Thr Thr Tyr Leu Trp Glu Phe Leu Leu Asp Leu Leu Gln Asp 
        195                 200                 205             


Lys Asn Thr Cys Pro Arg Tyr Ile Lys Trp Thr Gln Arg Glu Lys Gly 
    210                 215                 220                 


Ile Phe Lys Leu Val Asp Ser Lys Ala Val Ser Lys Leu Trp Gly Lys 
225                 230                 235                 240 


His Lys Asn Lys Pro Asp Met Asn Tyr Glu Thr Met Gly Arg Ala Leu 
                245                 250                 255     


Arg Tyr Tyr Tyr Gln Arg Gly Ile Leu Ala Lys Val Glu Gly Gln Arg 
            260                 265                 270         


Leu Val Tyr Gln Phe Lys Asp Met Pro Lys Asn Ile Val Val Ile Asp 
        275                 280                 285             


Asp Asp Lys Ser Glu Thr Cys Asn Glu Asp Leu Ala Gly Thr Thr Asp 
    290                 295                 300                 


Glu Lys Ser Leu Glu Arg Val Ser Leu Ser Ala Glu Ser Leu Leu Lys 
305                 310                 315                 320 


Ala Ala Ser Ser Val Arg Ser Gly Lys Asn Ser Ser Pro Ile Asn Cys 
                325                 330                 335     


Ser Arg Ala Glu Lys Gly Val Ala Arg Val Val Asn Ile Thr Ser Pro 
            340                 345                 350         


Gly His Asp Ala Ser Ser Arg Ser Pro Thr Thr Thr Ala Ser Val Ser 
        355                 360                 365             


Ala Thr Ala Ala Pro Arg Thr Val Arg Val Ala Met Gln Val Pro Val 
    370                 375                 380                 


Val Met Thr Ser Leu Gly Gln Lys Ile Ser Thr Val Ala Val Gln Ser 
385                 390                 395                 400 


Val Asn Ala Gly Ala Pro Leu Ile Thr Ser Thr Ser Pro Thr Thr Ala 
                405                 410                 415     


Thr Ser Pro Lys Val Val Ile Gln Thr Ile Pro Thr Val Met Pro Ala 
            420                 425                 430         


Ser Thr Glu Asn Gly Asp Lys Ile Thr Met Gln Pro Ala Lys Ile Ile 
        435                 440                 445             


Thr Ile Pro Ala Thr Gln Leu Ala Gln Cys Gln Leu Gln Thr Lys Ser 
    450                 455                 460                 


Asn Leu Thr Gly Ser Gly Ser Ile Asn Ile Val Gly Thr Pro Leu Ala 
465                 470                 475                 480 


Val Arg Ala Leu Thr Pro Val Ser Ile Ala His Gly Thr Pro Val Met 
                485                 490                 495     


Arg Leu Ser Met Pro Thr Gln Gln Ala Ser Gly Gln Thr Pro Pro Arg 
            500                 505                 510         


Val Ile Ser Ala Val Ile Lys Gly Pro Glu Val Lys Ser Glu Ala Val 
        515                 520                 525             


Ala Lys Lys Gln Glu His Asp Val Lys Thr Leu Gln Leu Val Glu Glu 
    530                 535                 540                 


Lys Pro Ala Asp Gly Asn Lys Thr Val Thr His Val Val Val Val Ser 
545                 550                 555                 560 


Ala Pro Ser Ala Ile Ala Leu Pro Val Thr Met Lys Thr Glu Gly Leu 
                565                 570                 575     


Val Thr Cys Glu Lys 
            580     


<210>  3354
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  3354

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  3355
<211>  433
<212>  PRT
<213>  homo sapiens

<400>  3355

Met Gln Arg Met Ile Gln Gln Phe Ala Ala Glu Tyr Thr Ser Lys Asn 
1               5                   10                  15      


Ser Ser Thr Gln Asp Pro Ser Gln Pro Asn Ser Thr Lys Asn Gln Ser 
            20                  25                  30          


Leu Pro Lys Ala Ser Pro Val Thr Thr Ser Pro Thr Ala Ala Thr Thr 
        35                  40                  45              


Gln Asn Pro Val Leu Ser Lys Leu Leu Met Ala Asp Gln Asp Ser Pro 
    50                  55                  60                  


Leu Asp Leu Thr Val Arg Lys Ser Gln Ser Glu Pro Ser Glu Gln Asp 
65                  70                  75                  80  


Gly Val Leu Asp Leu Ser Thr Lys Lys Ser Pro Cys Ala Gly Ser Thr 
                85                  90                  95      


Ser Leu Ser His Ser Pro Gly Cys Ser Ser Thr Gln Gly Asn Gly Arg 
            100                 105                 110         


Pro Gly Arg Pro Ser Gln Tyr Arg Pro Asp Gly Leu Arg Ser Gly Asp 
        115                 120                 125             


Gly Val Pro Pro Arg Ser Leu Gln Asp Gly Thr Arg Glu Gly Phe Gly 
    130                 135                 140                 


His Ser Thr Ser Leu Lys Val Pro Leu Ala Arg Ser Leu Gln Ile Ser 
145                 150                 155                 160 


Glu Glu Leu Leu Ser Arg Asn Gln Leu Ser Thr Ala Ala Ser Leu Gly 
                165                 170                 175     


Pro Ser Gly Leu Gln Asn His Gly Gln His Leu Ile Leu Ser Arg Glu 
            180                 185                 190         


Ala Ser Trp Ala Lys Pro His Tyr Glu Phe Asn Leu Ser Arg Met Lys 
        195                 200                 205             


Phe Arg Gly Asn Gly Ala Leu Ser Asn Ile Ser Asp Leu Pro Phe Leu 
    210                 215                 220                 


Ala Glu Asn Ser Ala Phe Pro Lys Met Ala Leu Gln Ala Lys Gln Asp 
225                 230                 235                 240 


Gly Lys Lys Asp Val Ser His Ser Ser Pro Val Asp Leu Lys Ile Pro 
                245                 250                 255     


Gln Val Arg Gly Met Asp Leu Ser Trp Glu Ser Arg Thr Gly Asp Gln 
            260                 265                 270         


Tyr Ser Tyr Ser Ser Leu Val Met Gly Ser Gln Thr Glu Ser Ala Leu 
        275                 280                 285             


Ser Lys Lys Leu Arg Ala Ile Leu Pro Lys Gln Ser Arg Lys Ser Met 
    290                 295                 300                 


Leu Asp Ala Gly Pro Asp Ser Trp Gly Ser Asp Ala Glu Gln Ser Thr 
305                 310                 315                 320 


Ser Gly Gln Pro Tyr Pro Thr Ser Asp Gln Glu Gly Asp Pro Gly Ser 
                325                 330                 335     


Lys Gln Pro Arg Lys Lys Arg Gly Arg Tyr Arg Gln Tyr Asn Ser Glu 
            340                 345                 350         


Ile Leu Glu Glu Ala Ile Ser Val Val Met Ser Gly Lys Met Ser Val 
        355                 360                 365             


Ser Lys Ala Gln Ser Ile Tyr Gly Ile Pro His Ser Thr Leu Glu Tyr 
    370                 375                 380                 


Lys Val Lys Glu Arg Leu Gly Thr Leu Lys Asn Pro Pro Lys Lys Lys 
385                 390                 395                 400 


Met Lys Leu Met Arg Ser Glu Gly Pro Asp Val Ser Val Lys Ile Glu 
                405                 410                 415     


Leu Asp Pro Gln Gly Glu Ala Ala Gln Ser Ala Asn Glu Ser Lys Asn 
            420                 425                 430         


Glu 
    


<210>  3356
<211>  214
<212>  PRT
<213>  homo sapiens

<400>  3356

Met Phe Cys Gln Leu Ala Lys Thr Cys Pro Val Gln Leu Trp Val Asp 
1               5                   10                  15      


Ser Thr Pro Pro Pro Gly Thr Arg Val Arg Ala Met Ala Ile Tyr Lys 
            20                  25                  30          


Gln Ser Gln His Met Thr Glu Val Val Arg Arg Cys Pro His His Glu 
        35                  40                  45              


Arg Cys Ser Asp Ser Asp Gly Leu Ala Pro Pro Gln His Leu Ile Arg 
    50                  55                  60                  


Val Glu Gly Asn Leu Arg Val Glu Tyr Leu Asp Asp Arg Asn Thr Phe 
65                  70                  75                  80  


Arg His Ser Val Val Val Pro Tyr Glu Pro Pro Glu Val Gly Ser Asp 
                85                  90                  95      


Cys Thr Thr Ile His Tyr Asn Tyr Met Cys Asn Ser Ser Cys Met Gly 
            100                 105                 110         


Gly Met Asn Arg Arg Pro Ile Leu Thr Ile Ile Thr Leu Glu Asp Ser 
        115                 120                 125             


Ser Gly Asn Leu Leu Gly Arg Asn Ser Phe Glu Val Arg Val Cys Ala 
    130                 135                 140                 


Cys Pro Gly Arg Asp Arg Arg Thr Glu Glu Glu Asn Leu Arg Lys Lys 
145                 150                 155                 160 


Gly Glu Pro His His Glu Leu Pro Pro Gly Ser Thr Lys Arg Ala Leu 
                165                 170                 175     


Pro Asn Asn Thr Ser Ser Ser Pro Gln Pro Lys Lys Lys Pro Leu Asp 
            180                 185                 190         


Gly Glu Tyr Phe Thr Leu Gln Met Leu Leu Asp Leu Arg Trp Cys Tyr 
        195                 200                 205             


Phe Leu Ile Asn Ser Ser 
    210                 


<210>  3357
<211>  504
<212>  PRT
<213>  homo sapiens

<400>  3357

Met Pro Thr Val Glu Glu Leu Tyr Arg Asn Tyr Gly Ile Leu Ala Asp 
1               5                   10                  15      


Ala Thr Glu Gln Val Gly Gln His Lys Asp Ala Tyr Gln Val Ile Leu 
            20                  25                  30          


Asp Gly Val Lys Gly Gly Thr Lys Glu Lys Arg Leu Ala Ala Gln Phe 
        35                  40                  45              


Ile Pro Lys Phe Phe Lys His Phe Pro Glu Leu Ala Asp Ser Ala Ile 
    50                  55                  60                  


Asn Ala Gln Leu Asp Leu Cys Glu Asp Glu Asp Val Ser Ile Arg Arg 
65                  70                  75                  80  


Gln Ala Ile Lys Glu Leu Pro Gln Phe Ala Thr Gly Glu Asn Leu Pro 
                85                  90                  95      


Arg Val Ala Asp Ile Leu Thr Gln Leu Leu Gln Thr Asp Asp Ser Ala 
            100                 105                 110         


Glu Phe Asn Leu Val Asn Asn Ala Leu Leu Ser Ile Phe Lys Met Asp 
        115                 120                 125             


Ala Lys Gly Thr Leu Gly Gly Leu Phe Ser Gln Ile Leu Gln Gly Glu 
    130                 135                 140                 


Asp Ile Val Arg Glu Arg Ala Ile Lys Phe Leu Ser Thr Lys Leu Lys 
145                 150                 155                 160 


Thr Leu Pro Asp Glu Val Leu Thr Lys Glu Val Glu Glu Leu Ile Leu 
                165                 170                 175     


Thr Glu Ser Lys Lys Val Leu Glu Asp Val Thr Gly Glu Glu Phe Val 
            180                 185                 190         


Leu Phe Met Lys Ile Leu Ser Gly Leu Lys Ser Leu Gln Thr Val Ser 
        195                 200                 205             


Gly Arg Gln Gln Leu Val Glu Leu Val Ala Glu Gln Ala Asp Leu Glu 
    210                 215                 220                 


Gln Thr Phe Asn Pro Ser Asp Pro Asp Cys Val Asp Arg Leu Leu Gln 
225                 230                 235                 240 


Cys Thr Arg Gln Ala Val Pro Leu Phe Ser Lys Asn Val His Ser Thr 
                245                 250                 255     


Arg Phe Val Thr Tyr Phe Cys Glu Gln Val Leu Pro Asn Leu Gly Thr 
            260                 265                 270         


Leu Thr Thr Pro Val Glu Gly Leu Asp Ile Gln Leu Glu Val Leu Lys 
        275                 280                 285             


Leu Leu Ala Glu Met Ser Ser Phe Cys Gly Asp Met Glu Lys Leu Glu 
    290                 295                 300                 


Thr Asn Leu Arg Lys Leu Phe Asp Lys Leu Leu Glu Tyr Met Pro Leu 
305                 310                 315                 320 


Pro Pro Glu Glu Ala Glu Asn Gly Glu Asn Ala Gly Asn Glu Glu Pro 
                325                 330                 335     


Lys Leu Gln Phe Ser Tyr Val Glu Cys Leu Leu Tyr Ser Phe His Gln 
            340                 345                 350         


Leu Gly Arg Lys Leu Pro Asp Phe Leu Thr Ala Lys Leu Asn Ala Glu 
        355                 360                 365             


Lys Leu Lys Asp Phe Lys Ile Arg Leu Gln Tyr Phe Ala Arg Gly Leu 
    370                 375                 380                 


Gln Val Tyr Ile Arg Gln Leu Arg Leu Ala Leu Gln Gly Lys Thr Gly 
385                 390                 395                 400 


Glu Ala Leu Lys Thr Glu Glu Asn Lys Ile Lys Val Val Ala Leu Lys 
                405                 410                 415     


Ile Thr Asn Asn Ile Asn Val Leu Ile Lys Asp Leu Phe His Ile Pro 
            420                 425                 430         


Pro Ser Tyr Lys Ser Thr Val Thr Leu Ser Trp Lys Pro Val Gln Lys 
        435                 440                 445             


Val Glu Ile Gly Gln Lys Arg Ala Ser Glu Asp Thr Thr Ser Gly Ser 
    450                 455                 460                 


Pro Pro Lys Lys Ser Ser Ala Gly Pro Lys Arg Asp Ala Arg Gln Ile 
465                 470                 475                 480 


Tyr Asn Pro Pro Ser Gly Lys Tyr Ser Ser Asn Leu Gly Asn Phe Asn 
                485                 490                 495     


Tyr Glu Arg Ser Leu Gln Gly Lys 
            500                 


<210>  3358
<211>  906
<212>  PRT
<213>  homo sapiens

<400>  3358

Met Gln His Ile Phe Ala Phe Phe Cys Thr Gly Phe Leu Gly Ala Val 
1               5                   10                  15      


Val Gly Ala Asn Phe Pro Asn Asn Ile Gln Ile Gly Gly Leu Phe Pro 
            20                  25                  30          


Asn Gln Gln Ser Gln Glu His Ala Ala Phe Arg Phe Ala Leu Ser Gln 
        35                  40                  45              


Leu Thr Glu Pro Pro Lys Leu Leu Pro Gln Ile Asp Ile Val Asn Ile 
    50                  55                  60                  


Ser Asp Ser Phe Glu Met Thr Tyr Arg Phe Cys Ser Gln Phe Ser Lys 
65                  70                  75                  80  


Gly Val Tyr Ala Ile Phe Gly Phe Tyr Glu Arg Arg Thr Val Asn Met 
                85                  90                  95      


Leu Thr Ser Phe Cys Gly Ala Leu His Val Cys Phe Ile Thr Pro Ser 
            100                 105                 110         


Phe Pro Val Asp Thr Ser Asn Gln Phe Val Leu Gln Leu Arg Pro Glu 
        115                 120                 125             


Leu Gln Asp Ala Leu Ile Ser Ile Ile Asp His Tyr Lys Trp Gln Lys 
    130                 135                 140                 


Phe Val Tyr Ile Tyr Asp Ala Asp Arg Gly Leu Ser Val Leu Gln Lys 
145                 150                 155                 160 


Val Leu Asp Thr Ala Ala Glu Lys Asn Trp Gln Val Thr Ala Val Asn 
                165                 170                 175     


Ile Leu Thr Thr Thr Glu Glu Gly Tyr Arg Met Leu Phe Gln Asp Leu 
            180                 185                 190         


Glu Lys Lys Lys Glu Arg Leu Val Val Val Asp Cys Glu Ser Glu Arg 
        195                 200                 205             


Leu Asn Ala Ile Leu Gly Gln Ile Ile Lys Leu Glu Lys Asn Gly Ile 
    210                 215                 220                 


Gly Tyr His Tyr Ile Leu Ala Asn Leu Gly Phe Met Asp Ile Asp Leu 
225                 230                 235                 240 


Asn Lys Phe Lys Glu Ser Gly Ala Asn Val Thr Gly Phe Gln Leu Val 
                245                 250                 255     


Asn Tyr Thr Asp Thr Ile Pro Ala Lys Ile Met Gln Gln Trp Lys Asn 
            260                 265                 270         


Ser Asp Ala Arg Asp His Thr Arg Val Asp Trp Lys Arg Pro Lys Tyr 
        275                 280                 285             


Thr Ser Ala Leu Thr Tyr Asp Gly Val Lys Val Met Ala Glu Ala Phe 
    290                 295                 300                 


Gln Ser Leu Arg Arg Gln Arg Ile Asp Ile Ser Arg Arg Gly Asn Ala 
305                 310                 315                 320 


Gly Asp Cys Leu Ala Asn Pro Ala Val Pro Trp Gly Gln Gly Ile Asp 
                325                 330                 335     


Ile Gln Arg Ala Leu Gln Gln Val Arg Phe Glu Gly Leu Thr Gly Asn 
            340                 345                 350         


Val Gln Phe Asn Glu Lys Gly Arg Arg Thr Asn Tyr Thr Leu His Val 
        355                 360                 365             


Ile Glu Met Lys His Asp Gly Ile Arg Lys Ile Gly Tyr Trp Asn Glu 
    370                 375                 380                 


Asp Asp Lys Phe Val Pro Ala Ala Thr Asp Ala Gln Ala Gly Gly Asp 
385                 390                 395                 400 


Asn Ser Ser Val Gln Asn Arg Thr Tyr Ile Val Thr Thr Ile Leu Glu 
                405                 410                 415     


Asp Pro Tyr Val Met Leu Lys Lys Asn Ala Asn Gln Phe Glu Gly Asn 
            420                 425                 430         


Asp Arg Tyr Glu Gly Tyr Cys Val Glu Leu Ala Ala Glu Ile Ala Lys 
        435                 440                 445             


His Val Gly Tyr Ser Tyr Arg Leu Glu Ile Val Ser Asp Gly Lys Tyr 
    450                 455                 460                 


Gly Ala Arg Asp Pro Asp Thr Lys Ala Trp Asn Gly Met Val Gly Glu 
465                 470                 475                 480 


Leu Val Tyr Gly Arg Ala Asp Val Ala Val Ala Pro Leu Thr Ile Thr 
                485                 490                 495     


Leu Val Arg Glu Glu Val Ile Asp Phe Ser Lys Pro Phe Met Ser Leu 
            500                 505                 510         


Gly Ile Ser Ile Met Ile Lys Lys Pro Gln Lys Ser Lys Pro Gly Val 
        515                 520                 525             


Phe Ser Phe Leu Asp Pro Leu Ala Tyr Glu Ile Trp Met Cys Ile Val 
    530                 535                 540                 


Phe Ala Tyr Ile Gly Val Ser Val Val Leu Phe Leu Val Ser Arg Phe 
545                 550                 555                 560 


Ser Pro Tyr Glu Trp His Ser Glu Glu Phe Glu Glu Gly Arg Asp Gln 
                565                 570                 575     


Thr Thr Ser Asp Gln Ser Asn Glu Phe Gly Ile Phe Asn Ser Leu Trp 
            580                 585                 590         


Phe Ser Leu Gly Ala Phe Met Gln Gln Gly Cys Asp Ile Ser Pro Arg 
        595                 600                 605             


Ser Leu Ser Gly Arg Ile Val Gly Gly Val Trp Trp Phe Phe Thr Leu 
    610                 615                 620                 


Ile Ile Ile Ser Ser Tyr Thr Ala Asn Leu Ala Ala Phe Leu Thr Val 
625                 630                 635                 640 


Glu Arg Met Val Ser Pro Ile Glu Ser Ala Glu Asp Leu Ala Lys Gln 
                645                 650                 655     


Thr Glu Ile Ala Tyr Gly Thr Leu Glu Ala Gly Ser Thr Lys Glu Phe 
            660                 665                 670         


Phe Arg Arg Ser Lys Ile Ala Val Phe Glu Lys Met Trp Thr Tyr Met 
        675                 680                 685             


Lys Ser Ala Glu Pro Ser Val Phe Val Arg Thr Thr Glu Glu Gly Met 
    690                 695                 700                 


Ile Arg Val Arg Lys Ser Lys Gly Lys Tyr Ala Tyr Leu Leu Glu Ser 
705                 710                 715                 720 


Thr Met Asn Glu Tyr Ile Glu Gln Arg Lys Pro Cys Asp Thr Met Lys 
                725                 730                 735     


Val Gly Gly Asn Leu Asp Ser Lys Gly Tyr Gly Ile Ala Thr Pro Lys 
            740                 745                 750         


Gly Ser Ala Leu Arg Asn Pro Val Asn Leu Ala Val Leu Lys Leu Asn 
        755                 760                 765             


Glu Gln Gly Leu Leu Asp Lys Leu Lys Asn Lys Trp Trp Tyr Asp Lys 
    770                 775                 780                 


Gly Glu Cys Gly Ser Gly Gly Gly Asp Ser Lys Asp Lys Thr Ser Ala 
785                 790                 795                 800 


Leu Ser Leu Ser Asn Val Ala Gly Val Phe Tyr Ile Leu Ile Gly Gly 
                805                 810                 815     


Leu Gly Leu Ala Met Leu Val Ala Leu Ile Glu Phe Cys Tyr Lys Ser 
            820                 825                 830         


Arg Ser Glu Ser Lys Arg Met Lys Gly Phe Cys Leu Ile Pro Gln Gln 
        835                 840                 845             


Ser Ile Asn Glu Ala Ile Arg Thr Ser Thr Leu Pro Arg Asn Ser Gly 
    850                 855                 860                 


Ala Gly Ala Ser Ser Gly Gly Ser Gly Glu Asn Gly Arg Val Val Ser 
865                 870                 875                 880 


His Asp Phe Pro Lys Ser Met Gln Ser Ile Pro Cys Met Ser His Ser 
                885                 890                 895     


Ser Gly Met Pro Leu Gly Ala Thr Gly Leu 
            900                 905     


<210>  3359
<211>  979
<212>  PRT
<213>  homo sapiens

<400>  3359

Met Ala Thr Gln Ala Tyr Thr Glu Leu Gln Ala Ala Pro Pro Pro Ser 
1               5                   10                  15      


Gln Pro Pro Gln Ala Pro Pro Gln Ala Gln Pro Gln Pro Pro Pro Pro 
            20                  25                  30          


Pro Pro Pro Ala Ala Pro Gln Pro Pro Gln Pro Pro Thr Ala Ala Ala 
        35                  40                  45              


Thr Pro Gln Pro Gln Tyr Val Thr Glu Leu Gln Ser Pro Gln Pro Gln 
    50                  55                  60                  


Ala Gln Pro Pro Gly Gly Gln Lys Gln Tyr Val Thr Glu Leu Pro Ala 
65                  70                  75                  80  


Val Pro Ala Pro Ser Gln Pro Thr Gly Ala Pro Thr Pro Ser Pro Ala 
                85                  90                  95      


Pro Gln Gln Tyr Ile Val Val Thr Val Ser Glu Gly Ala Met Arg Ala 
            100                 105                 110         


Ser Glu Thr Val Ser Glu Ala Ser Pro Gly Ser Thr Ala Ser Gln Thr 
        115                 120                 125             


Gly Val Pro Thr Gln Val Val Gln Gln Val Gln Gly Thr Gln Gln Arg 
    130                 135                 140                 


Leu Leu Val Gln Thr Ser Val Gln Ala Lys Pro Gly His Val Ser Pro 
145                 150                 155                 160 


Leu Gln Leu Thr Asn Ile Gln Val Pro Gln Gln Ala Leu Pro Thr Gln 
                165                 170                 175     


Arg Leu Val Val Gln Ser Ala Ala Pro Gly Ser Lys Gly Gly Gln Val 
            180                 185                 190         


Ser Leu Thr Val His Gly Thr Gln Gln Val His Ser Pro Pro Glu Gln 
        195                 200                 205             


Ser Pro Val Gln Ala Asn Ser Ser Ser Ser Lys Thr Ala Gly Ala Pro 
    210                 215                 220                 


Thr Gly Thr Val Pro Gln Gln Leu Gln Val His Gly Val Gln Gln Ser 
225                 230                 235                 240 


Val Pro Val Thr Gln Glu Arg Ser Val Val Gln Ala Thr Pro Gln Ala 
                245                 250                 255     


Pro Lys Pro Gly Pro Val Gln Pro Leu Thr Val Gln Gly Leu Gln Pro 
            260                 265                 270         


Val His Val Ala Gln Glu Val Gln Gln Leu Gln Gln Val Pro Val Pro 
        275                 280                 285             


His Val Tyr Ser Ser Gln Val Gln Tyr Val Glu Gly Gly Asp Ala Ser 
    290                 295                 300                 


Tyr Thr Ala Ser Ala Ile Arg Ser Ser Thr Tyr Ser Tyr Pro Glu Thr 
305                 310                 315                 320 


Pro Leu Tyr Thr Gln Thr Ala Ser Thr Ser Tyr Tyr Glu Ala Ala Gly 
                325                 330                 335     


Thr Ala Thr Gln Val Ser Thr Pro Ala Thr Ser Gln Ala Val Ala Ser 
            340                 345                 350         


Ser Gly Ser Met Pro Met Tyr Val Ser Gly Ser Gln Val Val Ala Ser 
        355                 360                 365             


Ser Thr Ser Thr Gly Ala Gly Ala Ser Asn Ser Ser Gly Gly Gly Gly 
    370                 375                 380                 


Ser Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ser 
385                 390                 395                 400 


Gly Ser Thr Gly Gly Gly Gly Ser Gly Ala Gly Thr Tyr Val Ile Gln 
                405                 410                 415     


Gly Gly Tyr Met Leu Gly Ser Ala Ser Gln Ser Tyr Ser His Thr Thr 
            420                 425                 430         


Arg Ala Ser Pro Ala Thr Val Gln Trp Leu Leu Asp Asn Tyr Glu Thr 
        435                 440                 445             


Ala Glu Gly Val Ser Leu Pro Arg Ser Thr Leu Tyr Cys His Tyr Leu 
    450                 455                 460                 


Leu His Cys Gln Glu Gln Lys Leu Glu Pro Val Asn Ala Ala Ser Phe 
465                 470                 475                 480 


Gly Lys Leu Ile Arg Ser Val Phe Met Gly Leu Arg Thr Arg Arg Leu 
                485                 490                 495     


Gly Thr Arg Gly Asn Ser Lys Tyr His Tyr Tyr Gly Leu Arg Ile Lys 
            500                 505                 510         


Ala Ser Ser Pro Leu Leu Arg Leu Met Glu Asp Gln Gln His Met Ala 
        515                 520                 525             


Met Arg Gly Gln Pro Phe Ser Gln Lys Gln Arg Leu Lys Pro Ile Gln 
    530                 535                 540                 


Lys Met Glu Gly Met Thr Asn Gly Val Ala Val Gly Gln Gln Pro Ser 
545                 550                 555                 560 


Thr Gly Leu Ser Asp Ile Ser Ala Gln Val Gln Gln Tyr Gln Gln Phe 
                565                 570                 575     


Leu Asp Ala Ser Arg Ser Leu Pro Asp Phe Thr Glu Leu Asp Leu Gln 
            580                 585                 590         


Gly Lys Val Leu Pro Glu Gly Val Gly Pro Gly Asp Ile Lys Ala Phe 
        595                 600                 605             


Gln Val Leu Tyr Arg Glu His Cys Glu Ala Ile Val Asp Val Met Val 
    610                 615                 620                 


Asn Leu Gln Phe Thr Leu Val Glu Thr Leu Trp Lys Thr Phe Trp Arg 
625                 630                 635                 640 


Tyr Asn Leu Ser Gln Pro Ser Glu Ala Pro Pro Leu Ala Val His Asp 
                645                 650                 655     


Glu Ala Glu Lys Arg Leu Pro Lys Ala Ile Leu Val Leu Leu Ser Lys 
            660                 665                 670         


Phe Glu Pro Val Leu Gln Trp Thr Lys His Cys Asp Asn Val Leu Tyr 
        675                 680                 685             


Gln Gly Leu Val Glu Ile Leu Ile Pro Asp Val Leu Arg Pro Ile Pro 
    690                 695                 700                 


Ser Ala Leu Thr Gln Ala Ile Arg Asn Phe Ala Lys Ser Leu Glu Ser 
705                 710                 715                 720 


Trp Leu Thr His Ala Met Val Asn Ile Pro Glu Glu Met Leu Arg Val 
                725                 730                 735     


Lys Val Ala Ala Ala Gly Ala Phe Ala Gln Thr Leu Arg Arg Tyr Thr 
            740                 745                 750         


Ser Leu Asn His Leu Ala Gln Ala Ala Arg Ala Val Leu Gln Asn Thr 
        755                 760                 765             


Ala Gln Ile Asn Gln Met Leu Ser Asp Leu Asn Arg Val Asp Phe Ala 
    770                 775                 780                 


Asn Val Gln Glu Gln Ala Ser Trp Val Cys Arg Cys Glu Asp Arg Val 
785                 790                 795                 800 


Val Gln Arg Leu Glu Gln Asp Phe Lys Val Thr Leu Gln Gln Gln Asn 
                805                 810                 815     


Ser Leu Glu Gln Trp Ala Ala Trp Leu Asp Gly Val Val Ser Gln Val 
            820                 825                 830         


Leu Lys Pro Tyr Gln Gly Ser Ala Gly Phe Pro Lys Ala Ala Lys Leu 
        835                 840                 845             


Phe Leu Leu Lys Trp Ser Phe Tyr Ser Ser Met Val Ile Arg Asp Leu 
    850                 855                 860                 


Thr Leu Arg Ser Ala Ala Ser Phe Gly Ser Phe His Leu Ile Arg Leu 
865                 870                 875                 880 


Leu Tyr Asp Glu Tyr Met Tyr Tyr Leu Ile Glu His Arg Val Ala Gln 
                885                 890                 895     


Ala Lys Gly Glu Thr Pro Ile Ala Val Met Gly Glu Phe Ala Asn Leu 
            900                 905                 910         


Ala Thr Ser Leu Asn Pro Leu Asp Pro Asp Lys Asp Glu Glu Glu Glu 
        915                 920                 925             


Glu Glu Glu Glu Ser Glu Asp Glu Leu Pro Gln Asp Ile Ser Leu Ala 
    930                 935                 940                 


Ala Gly Gly Glu Ser Pro Ala Leu Gly Pro Glu Thr Leu Glu Pro Pro 
945                 950                 955                 960 


Ala Lys Leu Ala Arg Thr Asp Ala Arg Gly Leu Phe Val Gln Ala Leu 
                965                 970                 975     


Pro Ser Ser 
            


<210>  3360
<211>  524
<212>  PRT
<213>  homo sapiens

<400>  3360

Met Pro Thr Val Glu Glu Leu Tyr Arg Asn Tyr Gly Ile Leu Ala Asp 
1               5                   10                  15      


Ala Thr Glu Gln Val Gly Gln His Lys Asp Ala Tyr Gln Val Ile Leu 
            20                  25                  30          


Asp Gly Val Lys Gly Gly Thr Lys Glu Lys Arg Leu Ala Ala Gln Phe 
        35                  40                  45              


Ile Pro Lys Phe Phe Lys His Phe Pro Glu Leu Ala Asp Ser Ala Ile 
    50                  55                  60                  


Asn Ala Gln Leu Asp Leu Cys Glu Asp Glu Asp Val Ser Ile Arg Arg 
65                  70                  75                  80  


Gln Ala Ile Lys Glu Leu Pro Gln Phe Ala Thr Gly Glu Asn Leu Pro 
                85                  90                  95      


Arg Val Ala Asp Ile Leu Thr Gln Leu Leu Gln Thr Asp Asp Ser Ala 
            100                 105                 110         


Glu Phe Asn Leu Val Asn Asn Ala Leu Leu Ser Ile Phe Lys Met Asp 
        115                 120                 125             


Ala Lys Gly Thr Leu Gly Gly Leu Phe Ser Gln Ile Leu Gln Gly Glu 
    130                 135                 140                 


Asp Ile Val Arg Glu Arg Ala Ile Lys Phe Leu Ser Thr Lys Leu Lys 
145                 150                 155                 160 


Thr Leu Pro Asp Glu Val Leu Thr Lys Glu Val Glu Glu Leu Ile Leu 
                165                 170                 175     


Thr Glu Ser Lys Lys Val Leu Glu Asp Val Thr Gly Glu Glu Phe Val 
            180                 185                 190         


Leu Phe Met Lys Ile Leu Ser Gly Leu Lys Ser Leu Gln Thr Val Ser 
        195                 200                 205             


Gly Arg Gln Gln Leu Val Glu Leu Val Ala Glu Gln Ala Asp Leu Glu 
    210                 215                 220                 


Gln Thr Phe Asn Pro Ser Asp Pro Asp Cys Val Asp Arg Leu Leu Gln 
225                 230                 235                 240 


Cys Thr Arg Gln Ala Val Pro Leu Phe Ser Lys Asn Val His Ser Thr 
                245                 250                 255     


Arg Phe Val Thr Tyr Phe Cys Glu Gln Val Leu Pro Asn Leu Gly Thr 
            260                 265                 270         


Leu Thr Thr Pro Val Glu Gly Leu Asp Ile Gln Leu Glu Val Leu Lys 
        275                 280                 285             


Leu Leu Ala Glu Met Ser Ser Phe Cys Gly Asp Met Glu Lys Leu Glu 
    290                 295                 300                 


Thr Asn Leu Arg Lys Leu Phe Asp Lys Leu Leu Glu Tyr Met Pro Leu 
305                 310                 315                 320 


Pro Pro Glu Glu Ala Glu Asn Gly Glu Asn Ala Gly Asn Glu Glu Pro 
                325                 330                 335     


Lys Leu Gln Phe Ser Tyr Val Glu Cys Leu Leu Tyr Ser Phe His Gln 
            340                 345                 350         


Leu Gly Arg Lys Leu Pro Asp Phe Leu Thr Ala Lys Leu Asn Ala Glu 
        355                 360                 365             


Lys Leu Lys Asp Phe Lys Ile Arg Leu Gln Tyr Phe Ala Arg Gly Leu 
    370                 375                 380                 


Gln Val Tyr Ile Arg Gln Leu Arg Leu Ala Leu Gln Gly Lys Thr Gly 
385                 390                 395                 400 


Glu Ala Leu Lys Thr Glu Glu Asn Lys Ile Lys Val Val Ala Leu Lys 
                405                 410                 415     


Ile Thr Asn Asn Ile Asn Val Leu Ile Lys Asp Leu Phe His Ile Pro 
            420                 425                 430         


Pro Ser Tyr Lys Ser Thr Val Thr Leu Ser Trp Lys Pro Val Gln Lys 
        435                 440                 445             


Val Glu Ile Gly Gln Lys Arg Ala Ser Glu Asp Thr Thr Ser Gly Ser 
    450                 455                 460                 


Pro Pro Lys Lys Ser Ser Ala Gly Pro Lys Arg Asp Ala Arg Gln Ile 
465                 470                 475                 480 


Tyr Asn Pro Pro Ser Gly Lys Tyr Ser Ser Asn Leu Gly Asn Phe Asn 
                485                 490                 495     


Tyr Glu Gln Arg Gly Ala Phe Arg Gly Ser Arg Gly Gly Arg Gly Trp 
            500                 505                 510         


Gly Thr Arg Gly Asn Arg Ser Arg Gly Arg Leu Tyr 
        515                 520                 


<210>  3361
<211>  179
<212>  PRT
<213>  homo sapiens

<400>  3361

Met Gln Arg Gln Asn Phe Arg Pro Pro Thr Pro Pro Tyr Pro Gly Pro 
1               5                   10                  15      


Gly Gly Gly Gly Trp Gly Ser Gly Ser Ser Phe Arg Gly Thr Pro Gly 
            20                  25                  30          


Gly Gly Gly Pro Arg Pro Pro Ser Pro Arg Asp Gly Tyr Gly Ser Pro 
        35                  40                  45              


His His Thr Pro Pro Tyr Gly Pro Arg Ser Arg Pro Tyr Gly Ser Ser 
    50                  55                  60                  


His Ser Pro Arg His Gly Gly Ser Phe Pro Gly Gly Arg Phe Gly Ser 
65                  70                  75                  80  


Pro Ser Pro Gly Gly Tyr Pro Gly Ser Tyr Ser Arg Ser Pro Ala Gly 
                85                  90                  95      


Ser Gln Gln Gln Phe Gly Tyr Ser Pro Gly Gln Gln Gln Thr His Pro 
            100                 105                 110         


Gln Gly Ser Pro Arg Thr Ser Thr Pro Phe Gly Ser Gly Arg Val Arg 
        115                 120                 125             


Glu Lys Arg Met Ser Asn Glu Leu Glu Asn Tyr Phe Lys Pro Ser Met 
    130                 135                 140                 


Leu Glu Asp Pro Trp Ala Gly Leu Glu Pro Val Ser Val Val Asp Ile 
145                 150                 155                 160 


Ser Gln Gln Tyr Ser Asn Thr Gln Thr Phe Thr Gly Lys Lys Gly Arg 
                165                 170                 175     


Tyr Phe Cys 
            


<210>  3362
<211>  636
<212>  PRT
<213>  homo sapiens

<400>  3362

Met Val Gln Arg Asp Met Ser Lys Ser Pro Pro Thr Ala Ala Ala Ala 
1               5                   10                  15      


Val Ala Gln Glu Ile Gln Met Glu Leu Leu Glu Asn Val Ala Pro Ala 
            20                  25                  30          


Gly Ala Leu Gly Ala Ala Ala Gln Ser Tyr Gly Lys Gly Ala Arg Arg 
        35                  40                  45              


Lys Asn Arg Phe Lys Gly Ser Asp Gly Ser Thr Ser Ser Asp Thr Thr 
    50                  55                  60                  


Ser Asn Ser Phe Val Arg Gln Gly Ser Ala Asp Ser Tyr Thr Ser Arg 
65                  70                  75                  80  


Pro Ser Asp Ser Asp Val Ser Leu Glu Glu Asp Arg Glu Ala Val Arg 
                85                  90                  95      


Arg Glu Ala Glu Arg Gln Ala Gln Ala Gln Leu Glu Lys Ala Lys Thr 
            100                 105                 110         


Lys Pro Val Ala Phe Ala Val Arg Thr Asn Val Ser Tyr Ser Ala Ala 
        115                 120                 125             


His Glu Asp Asp Val Pro Val Pro Gly Met Ala Ile Ser Phe Glu Ala 
    130                 135                 140                 


Lys Asp Phe Leu His Val Lys Glu Lys Phe Asn Asn Asp Trp Trp Ile 
145                 150                 155                 160 


Gly Arg Leu Val Lys Glu Gly Cys Glu Ile Gly Phe Ile Pro Ser Pro 
                165                 170                 175     


Val Lys Leu Glu Asn Met Arg Leu Gln His Glu Gln Arg Ala Lys Gln 
            180                 185                 190         


Gly Lys Phe Tyr Ser Ser Lys Ser Gly Gly Asn Ser Ser Ser Ser Leu 
        195                 200                 205             


Gly Asp Ile Val Pro Ser Ser Arg Lys Ser Thr Pro Pro Ser Ser Gly 
    210                 215                 220                 


Ala Lys Ser Ala Asp Glu Gln Asp Gln Trp Lys Thr Ala Gly Leu Phe 
225                 230                 235                 240 


Trp Arg Phe Thr Thr Glu His Thr Pro Pro Tyr Asp Val Val Pro Ser 
                245                 250                 255     


Met Arg Pro Val Val Leu Val Gly Pro Ser Leu Lys Gly Tyr Glu Val 
            260                 265                 270         


Thr Asp Met Met Gln Lys Ala Leu Phe Asp Phe Leu Lys His Arg Phe 
        275                 280                 285             


Glu Gly Arg Ile Ser Ile Thr Arg Val Thr Ala Asp Ile Ser Leu Ala 
    290                 295                 300                 


Lys Arg Ser Val Leu Asn Asn Pro Ser Lys His Ala Ile Ile Glu Arg 
305                 310                 315                 320 


Ser Asn Thr Arg Ser Ser Leu Ala Glu Val Gln Ser Glu Ile Glu Arg 
                325                 330                 335     


Ile Phe Glu Leu Ala Arg Thr Leu Gln Leu Val Val Leu Asp Ala Asp 
            340                 345                 350         


Thr Ile Asn His Pro Ala Gln Leu Ser Lys Thr Ser Leu Ala Pro Ile 
        355                 360                 365             


Ile Val Tyr Val Lys Ile Ser Ser Pro Lys Val Leu Gln Arg Leu Ile 
    370                 375                 380                 


Lys Ser Arg Gly Lys Ser Gln Ala Lys His Leu Asn Val Gln Met Val 
385                 390                 395                 400 


Ala Ala Asp Lys Leu Ala Gln Cys Pro Pro Glu Leu Phe Asp Val Ile 
                405                 410                 415     


Leu Asp Glu Asn Gln Leu Glu Asp Ala Cys Glu His Leu Ala Asp Tyr 
            420                 425                 430         


Leu Glu Ala Tyr Trp Lys Ala Thr His Pro Pro Ser Ser Ser Leu Pro 
        435                 440                 445             


Asn Pro Leu Leu Ser Arg Thr Leu Ala Thr Ser Ser Leu Pro Leu Ser 
    450                 455                 460                 


Pro Thr Leu Ala Ser Asn Ser Gln Gly Ser Gln Gly Asp Gln Arg Thr 
465                 470                 475                 480 


Asp Arg Ser Ala Pro Ile Arg Ser Ala Ser Gln Ala Glu Glu Glu Pro 
                485                 490                 495     


Ser Val Glu Pro Val Lys Lys Ser Gln His Arg Ser Ser Ser Ser Ala 
            500                 505                 510         


Pro His His Asn His Arg Ser Gly Thr Ser Arg Gly Leu Ser Arg Gln 
        515                 520                 525             


Glu Thr Phe Asp Ser Glu Thr Gln Glu Ser Arg Asp Ser Ala Tyr Val 
    530                 535                 540                 


Glu Pro Lys Glu Asp Tyr Ser His Asp His Val Asp His Tyr Ala Ser 
545                 550                 555                 560 


His Arg Asp His Asn His Arg Asp Glu Thr His Gly Ser Ser Asp His 
                565                 570                 575     


Arg His Arg Glu Ser Arg His Arg Ser Arg Asp Val Asp Arg Glu Gln 
            580                 585                 590         


Asp His Asn Glu Cys Asn Lys Gln Arg Ser Arg His Lys Ser Lys Asp 
        595                 600                 605             


Arg Tyr Cys Glu Lys Asp Gly Glu Val Ile Ser Lys Lys Arg Asn Glu 
    610                 615                 620                 


Ala Gly Glu Trp Asn Arg Asp Val Tyr Ile Arg Gln 
625                 630                 635     


<210>  3363
<211>  357
<212>  PRT
<213>  homo sapiens

<400>  3363

Met Gly Gly Ala Val Ser Ala Gly Glu Asp Asn Asp Asp Leu Ile Asp 
1               5                   10                  15      


Asn Leu Lys Glu Ala Gln Tyr Ile Arg Thr Glu Arg Val Glu Gln Ala 
            20                  25                  30          


Phe Arg Ala Ile Asp Arg Gly Asp Tyr Tyr Leu Glu Gly Tyr Arg Asp 
        35                  40                  45              


Asn Ala Tyr Lys Asp Leu Ala Trp Lys His Gly Asn Ile His Leu Ser 
    50                  55                  60                  


Ala Pro Cys Ile Tyr Ser Glu Val Met Glu Ala Leu Lys Leu Gln Pro 
65                  70                  75                  80  


Gly Leu Ser Phe Leu Asn Leu Gly Ser Gly Thr Gly Tyr Leu Ser Thr 
                85                  90                  95      


Met Val Gly Leu Ile Leu Gly Pro Phe Gly Ile Asn His Gly Ile Glu 
            100                 105                 110         


Leu His Ser Asp Val Val Glu Tyr Ala Lys Glu Lys Leu Glu Ser Phe 
        115                 120                 125             


Ile Lys Asn Ser Asp Ser Phe Asp Lys Phe Glu Phe Cys Glu Pro Ala 
    130                 135                 140                 


Phe Val Val Gly Asn Cys Leu Gln Ile Ala Ser Asp Ser His Gln Tyr 
145                 150                 155                 160 


Asp Arg Ile Tyr Cys Gly Ala Gly Val Gln Lys Asp His Glu Asn Tyr 
                165                 170                 175     


Met Lys Ile Leu Leu Lys Val Gly Gly Ile Leu Val Met Pro Ile Glu 
            180                 185                 190         


Asp Gln Leu Thr Gln Ile Met Arg Thr Gly Gln Asn Thr Trp Glu Ser 
        195                 200                 205             


Lys Asn Ile Leu Ala Val Ser Phe Ala Pro Leu Val Gln Pro Ser Lys 
    210                 215                 220                 


Asn Asp Asn Gly Lys Pro Asp Ser Val Gly Leu Pro Pro Cys Ala Val 
225                 230                 235                 240 


Arg Asn Leu Gln Asp Leu Ala Arg Ile Tyr Ile Arg Arg Thr Leu Arg 
                245                 250                 255     


Asn Phe Ile Asn Asp Glu Met Gln Ala Lys Gly Ile Pro Gln Arg Ala 
            260                 265                 270         


Pro Pro Lys Arg Lys Arg Lys Arg Val Lys Gln Arg Ile Asn Thr Tyr 
        275                 280                 285             


Val Phe Val Gly Asn Gln Leu Ile Pro Gln Pro Leu Asp Ser Glu Glu 
    290                 295                 300                 


Asp Glu Lys Met Glu Glu Asp Asn Lys Glu Glu Glu Glu Lys Asp His 
305                 310                 315                 320 


Asn Glu Ala Met Lys Pro Glu Glu Pro Pro Gln Asn Leu Leu Arg Glu 
                325                 330                 335     


Lys Ile Met Lys Leu Pro Leu Pro Glu Ser Leu Lys Ala Tyr Leu Thr 
            340                 345                 350         


Tyr Phe Arg Asp Lys 
        355         


<210>  3364
<211>  906
<212>  PRT
<213>  homo sapiens

<400>  3364

Met Gln His Ile Phe Ala Phe Phe Cys Thr Gly Phe Leu Gly Ala Val 
1               5                   10                  15      


Val Gly Ala Asn Phe Pro Asn Asn Ile Gln Ile Gly Gly Leu Phe Pro 
            20                  25                  30          


Asn Gln Gln Ser Gln Glu His Ala Ala Phe Arg Phe Ala Leu Ser Gln 
        35                  40                  45              


Leu Thr Glu Pro Pro Lys Leu Leu Pro Gln Ile Asp Ile Val Asn Ile 
    50                  55                  60                  


Ser Asp Ser Phe Glu Met Thr Tyr Arg Phe Cys Ser Gln Phe Ser Lys 
65                  70                  75                  80  


Gly Val Tyr Ala Ile Phe Gly Phe Tyr Glu Arg Arg Thr Val Asn Met 
                85                  90                  95      


Leu Thr Ser Phe Cys Gly Ala Leu His Val Cys Phe Ile Thr Pro Ser 
            100                 105                 110         


Phe Pro Val Asp Thr Ser Asn Gln Phe Val Leu Gln Leu Arg Pro Glu 
        115                 120                 125             


Leu Gln Asp Ala Leu Ile Ser Ile Ile Asp His Tyr Lys Trp Gln Lys 
    130                 135                 140                 


Phe Val Tyr Ile Tyr Asp Ala Asp Arg Gly Leu Ser Val Leu Gln Lys 
145                 150                 155                 160 


Val Leu Asp Thr Ala Ala Glu Lys Asn Trp Gln Val Thr Ala Val Asn 
                165                 170                 175     


Ile Leu Thr Thr Thr Glu Glu Gly Tyr Arg Met Leu Phe Gln Asp Leu 
            180                 185                 190         


Glu Lys Lys Lys Glu Arg Leu Val Val Val Asp Cys Glu Ser Glu Arg 
        195                 200                 205             


Leu Asn Ala Ile Leu Gly Gln Ile Ile Lys Leu Glu Lys Asn Gly Ile 
    210                 215                 220                 


Gly Tyr His Tyr Ile Leu Ala Asn Leu Gly Phe Met Asp Ile Asp Leu 
225                 230                 235                 240 


Asn Lys Phe Lys Glu Ser Gly Ala Asn Val Thr Gly Phe Gln Leu Val 
                245                 250                 255     


Asn Tyr Thr Asp Thr Ile Pro Ala Lys Ile Met Gln Gln Trp Lys Asn 
            260                 265                 270         


Ser Asp Ala Arg Asp His Thr Arg Val Asp Trp Lys Arg Pro Lys Tyr 
        275                 280                 285             


Thr Ser Ala Leu Thr Tyr Asp Gly Val Lys Val Met Ala Glu Ala Phe 
    290                 295                 300                 


Gln Ser Leu Arg Arg Gln Arg Ile Asp Ile Ser Arg Arg Gly Asn Ala 
305                 310                 315                 320 


Gly Asp Cys Leu Ala Asn Pro Ala Val Pro Trp Gly Gln Gly Ile Asp 
                325                 330                 335     


Ile Gln Arg Ala Leu Gln Gln Val Arg Phe Glu Gly Leu Thr Gly Asn 
            340                 345                 350         


Val Gln Phe Asn Glu Lys Gly Arg Arg Thr Asn Tyr Thr Leu His Val 
        355                 360                 365             


Ile Glu Met Lys His Asp Gly Ile Arg Lys Ile Gly Tyr Trp Asn Glu 
    370                 375                 380                 


Asp Asp Lys Phe Val Pro Ala Ala Thr Asp Ala Gln Ala Gly Gly Asp 
385                 390                 395                 400 


Asn Ser Ser Val Gln Asn Arg Thr Tyr Ile Val Thr Thr Ile Leu Glu 
                405                 410                 415     


Asp Pro Tyr Val Met Leu Lys Lys Asn Ala Asn Gln Phe Glu Gly Asn 
            420                 425                 430         


Asp Arg Tyr Glu Gly Tyr Cys Val Glu Leu Ala Ala Glu Ile Ala Lys 
        435                 440                 445             


His Val Gly Tyr Ser Tyr Arg Leu Glu Ile Val Ser Asp Gly Lys Tyr 
    450                 455                 460                 


Gly Ala Arg Asp Pro Asp Thr Lys Ala Trp Asn Gly Met Val Gly Glu 
465                 470                 475                 480 


Leu Val Tyr Gly Arg Ala Asp Val Ala Val Ala Pro Leu Thr Ile Thr 
                485                 490                 495     


Leu Val Arg Glu Glu Val Ile Asp Phe Ser Lys Pro Phe Met Ser Leu 
            500                 505                 510         


Gly Ile Ser Ile Met Ile Lys Lys Pro Gln Lys Ser Lys Pro Gly Val 
        515                 520                 525             


Phe Ser Phe Leu Asp Pro Leu Ala Tyr Glu Ile Trp Met Cys Ile Val 
    530                 535                 540                 


Phe Ala Tyr Ile Gly Val Ser Val Val Leu Phe Leu Val Ser Arg Phe 
545                 550                 555                 560 


Ser Pro Tyr Glu Trp His Ser Glu Glu Phe Glu Glu Gly Arg Asp Gln 
                565                 570                 575     


Thr Thr Ser Asp Gln Ser Asn Glu Phe Gly Ile Phe Asn Ser Leu Trp 
            580                 585                 590         


Phe Ser Leu Gly Ala Phe Met Gln Gln Gly Cys Asp Ile Ser Pro Arg 
        595                 600                 605             


Ser Leu Ser Gly Arg Ile Val Gly Gly Val Trp Trp Phe Phe Thr Leu 
    610                 615                 620                 


Ile Ile Ile Ser Ser Tyr Thr Ala Asn Leu Ala Ala Phe Leu Thr Val 
625                 630                 635                 640 


Glu Arg Met Val Ser Pro Ile Glu Ser Ala Glu Asp Leu Ala Lys Gln 
                645                 650                 655     


Thr Glu Ile Ala Tyr Gly Thr Leu Glu Ala Gly Ser Thr Lys Glu Phe 
            660                 665                 670         


Phe Arg Arg Ser Lys Ile Ala Val Phe Glu Lys Met Trp Thr Tyr Met 
        675                 680                 685             


Lys Ser Ala Glu Pro Ser Val Phe Val Arg Thr Thr Glu Glu Gly Met 
    690                 695                 700                 


Ile Arg Val Arg Lys Ser Lys Gly Lys Tyr Ala Tyr Leu Leu Glu Ser 
705                 710                 715                 720 


Thr Met Asn Glu Tyr Ile Glu Gln Arg Lys Pro Cys Asp Thr Met Lys 
                725                 730                 735     


Val Gly Gly Asn Leu Asp Ser Lys Gly Tyr Gly Ile Ala Thr Pro Lys 
            740                 745                 750         


Gly Ser Ala Leu Arg Gly Pro Val Asn Leu Ala Val Leu Lys Leu Ser 
        755                 760                 765             


Glu Gln Gly Val Leu Asp Lys Leu Lys Ser Lys Trp Trp Tyr Asp Lys 
    770                 775                 780                 


Gly Glu Cys Gly Ser Lys Asp Ser Gly Ser Lys Asp Lys Thr Ser Ala 
785                 790                 795                 800 


Leu Ser Leu Ser Asn Val Ala Gly Val Phe Tyr Ile Leu Ile Gly Gly 
                805                 810                 815     


Leu Gly Leu Ala Met Leu Val Ala Leu Ile Glu Phe Cys Tyr Lys Ser 
            820                 825                 830         


Arg Ser Glu Ser Lys Arg Met Lys Gly Phe Cys Leu Ile Pro Gln Gln 
        835                 840                 845             


Ser Ile Asn Glu Ala Ile Arg Thr Ser Thr Leu Pro Arg Asn Ser Gly 
    850                 855                 860                 


Ala Gly Ala Ser Ser Gly Gly Ser Gly Glu Asn Gly Arg Val Val Ser 
865                 870                 875                 880 


His Asp Phe Pro Lys Ser Met Gln Ser Ile Pro Cys Met Ser His Ser 
                885                 890                 895     


Ser Gly Met Pro Leu Gly Ala Thr Gly Leu 
            900                 905     


<210>  3365
<211>  406
<212>  PRT
<213>  homo sapiens

<400>  3365

Met Leu Phe His Ser Leu Ser Gly Pro Glu Val His Gly Val Ile Asp 
1               5                   10                  15      


Glu Met Asp Arg Arg Ala Lys Ser Glu Ala Pro Ala Ile Ser Ser Ala 
            20                  25                  30          


Ile Asp Arg Gly Asp Thr Glu Thr Thr Met Pro Ser Ile Ser Ser Asp 
        35                  40                  45              


Arg Ala Ala Leu Cys Ala Gly Cys Gly Gly Lys Ile Ser Asp Arg Tyr 
    50                  55                  60                  


Tyr Leu Leu Ala Val Asp Lys Gln Trp His Met Arg Cys Leu Lys Cys 
65                  70                  75                  80  


Cys Glu Cys Lys Leu Asn Leu Glu Ser Glu Leu Thr Cys Phe Ser Lys 
                85                  90                  95      


Asp Gly Ser Ile Tyr Cys Lys Glu Asp Tyr Tyr Arg Arg Phe Ser Val 
            100                 105                 110         


Gln Arg Cys Ala Arg Cys His Leu Gly Ile Ser Ala Ser Glu Met Val 
        115                 120                 125             


Met Arg Ala Arg Asp Leu Val Tyr His Leu Asn Cys Phe Thr Cys Thr 
    130                 135                 140                 


Thr Cys Asn Lys Met Leu Thr Thr Gly Asp His Phe Gly Met Lys Asp 
145                 150                 155                 160 


Ser Leu Val Tyr Cys Arg Leu His Phe Glu Ala Leu Leu Gln Gly Glu 
                165                 170                 175     


Tyr Pro Ala His Phe Asn His Ala Asp Val Ala Ala Ala Ala Ala Ala 
            180                 185                 190         


Ala Ala Ala Ala Lys Ser Ala Gly Leu Gly Ala Ala Gly Ala Asn Pro 
        195                 200                 205             


Leu Gly Leu Pro Tyr Tyr Asn Gly Val Gly Thr Val Gln Lys Gly Arg 
    210                 215                 220                 


Pro Arg Lys Arg Lys Ser Pro Gly Pro Gly Ala Asp Leu Ala Ala Tyr 
225                 230                 235                 240 


Asn Ala Ala Leu Ser Cys Asn Glu Asn Asp Ala Glu His Leu Asp Arg 
                245                 250                 255     


Asp Gln Pro Tyr Pro Ser Ser Gln Lys Thr Lys Arg Met Arg Thr Ser 
            260                 265                 270         


Phe Lys His His Gln Leu Arg Thr Met Lys Ser Tyr Phe Ala Ile Asn 
        275                 280                 285             


His Asn Pro Asp Ala Lys Asp Leu Lys Gln Leu Ala Gln Lys Thr Gly 
    290                 295                 300                 


Leu Thr Lys Arg Val Leu Gln Val Trp Phe Gln Asn Ala Arg Ala Lys 
305                 310                 315                 320 


Phe Arg Arg Asn Leu Leu Arg Gln Glu Asn Thr Gly Val Asp Lys Ser 
                325                 330                 335     


Thr Asp Ala Ala Leu Gln Thr Gly Thr Pro Ser Gly Pro Ala Ser Glu 
            340                 345                 350         


Leu Ser Asn Ala Ser Leu Ser Pro Ser Ser Thr Pro Thr Thr Leu Thr 
        355                 360                 365             


Asp Leu Thr Ser Pro Thr Leu Pro Thr Val Thr Ser Val Leu Thr Ser 
    370                 375                 380                 


Val Pro Gly Asn Leu Glu Gly His Glu Pro His Ser Pro Ser Gln Thr 
385                 390                 395                 400 


Thr Leu Thr Asn Leu Phe 
                405     


<210>  3366
<211>  509
<212>  PRT
<213>  homo sapiens

<400>  3366

Met Asn Leu Leu Asp Pro Phe Met Lys Met Thr Asp Glu Gln Glu Lys 
1               5                   10                  15      


Gly Leu Ser Gly Ala Pro Ser Pro Thr Met Ser Glu Asp Ser Ala Gly 
            20                  25                  30          


Ser Pro Cys Pro Ser Gly Ser Gly Ser Asp Thr Glu Asn Thr Arg Pro 
        35                  40                  45              


Gln Glu Asn Thr Phe Pro Lys Gly Glu Pro Asp Leu Lys Lys Glu Ser 
    50                  55                  60                  


Glu Glu Asp Lys Phe Pro Val Cys Ile Arg Glu Ala Val Ser Gln Val 
65                  70                  75                  80  


Leu Lys Gly Tyr Asp Trp Thr Leu Val Pro Met Pro Val Arg Val Asn 
                85                  90                  95      


Gly Ser Ser Lys Asn Lys Pro His Val Lys Arg Pro Met Asn Ala Phe 
            100                 105                 110         


Met Val Trp Ala Gln Ala Ala Arg Arg Lys Leu Ala Asp Gln Tyr Pro 
        115                 120                 125             


His Leu His Asn Ala Glu Leu Ser Lys Thr Leu Gly Lys Leu Trp Arg 
    130                 135                 140                 


Leu Leu Asn Glu Ser Glu Lys Arg Pro Phe Val Glu Glu Ala Glu Arg 
145                 150                 155                 160 


Leu Arg Val Gln His Lys Lys Asp His Pro Asp Tyr Lys Tyr Gln Pro 
                165                 170                 175     


Arg Arg Arg Lys Ser Val Lys Asn Gly Gln Ala Glu Ala Glu Glu Ala 
            180                 185                 190         


Thr Glu Gln Thr His Ile Ser Pro Asn Ala Ile Phe Lys Ala Leu Gln 
        195                 200                 205             


Ala Asp Ser Pro His Ser Ser Ser Gly Met Ser Glu Val His Ser Pro 
    210                 215                 220                 


Gly Glu His Ser Gly Gln Ser Gln Gly Pro Pro Thr Pro Pro Thr Thr 
225                 230                 235                 240 


Pro Lys Thr Asp Val Gln Pro Gly Lys Ala Asp Leu Lys Arg Glu Gly 
                245                 250                 255     


Arg Pro Leu Pro Glu Gly Gly Arg Gln Pro Pro Ile Asp Phe Arg Asp 
            260                 265                 270         


Val Asp Ile Gly Glu Leu Ser Ser Asp Val Ile Ser Asn Ile Glu Thr 
        275                 280                 285             


Phe Asp Val Asn Glu Phe Asp Gln Tyr Leu Pro Pro Asn Gly His Pro 
    290                 295                 300                 


Gly Val Pro Ala Thr His Gly Gln Val Thr Tyr Thr Gly Ser Tyr Gly 
305                 310                 315                 320 


Ile Ser Ser Thr Ala Ala Thr Pro Ala Ser Ala Gly His Val Trp Met 
                325                 330                 335     


Ser Lys Gln Gln Ala Pro Pro Pro Pro Pro Gln Gln Pro Pro Gln Ala 
            340                 345                 350         


Pro Pro Ala Pro Gln Ala Pro Pro Gln Pro Gln Ala Ala Pro Pro Gln 
        355                 360                 365             


Gln Pro Ala Ala Pro Pro Gln Gln Pro Gln Ala His Thr Leu Thr Thr 
    370                 375                 380                 


Leu Ser Ser Glu Pro Gly Gln Ser Gln Arg Thr His Ile Lys Thr Glu 
385                 390                 395                 400 


Gln Leu Ser Pro Ser His Tyr Ser Glu Gln Gln Gln His Ser Pro Gln 
                405                 410                 415     


Gln Ile Ala Tyr Ser Pro Phe Asn Leu Pro His Tyr Ser Pro Ser Tyr 
            420                 425                 430         


Pro Pro Ile Thr Arg Ser Gln Tyr Asp Tyr Thr Asp His Gln Asn Ser 
        435                 440                 445             


Ser Ser Tyr Tyr Ser His Ala Ala Gly Gln Gly Thr Gly Leu Tyr Ser 
    450                 455                 460                 


Thr Phe Thr Tyr Met Asn Pro Ala Gln Arg Pro Met Tyr Thr Pro Ile 
465                 470                 475                 480 


Ala Asp Thr Ser Gly Val Pro Ser Ile Pro Gln Thr His Ser Pro Gln 
                485                 490                 495     


His Trp Glu Gln Pro Val Tyr Thr Gln Leu Thr Arg Pro 
            500                 505                 


<210>  3367
<211>  208
<212>  PRT
<213>  homo sapiens

<400>  3367

Met Ser Thr Gly Gly Asp Phe Gly Asn Pro Leu Arg Lys Phe Lys Leu 
1               5                   10                  15      


Val Phe Leu Gly Glu Gln Ser Val Gly Lys Thr Ser Leu Ile Thr Arg 
            20                  25                  30          


Phe Met Tyr Asp Ser Phe Asp Asn Thr Tyr Gln Ala Thr Ile Gly Ile 
        35                  40                  45              


Asp Phe Leu Ser Lys Thr Met Tyr Leu Glu Asp Arg Thr Ile Arg Leu 
    50                  55                  60                  


Gln Leu Trp Asp Thr Ala Gly Gln Glu Arg Phe Arg Ser Leu Ile Pro 
65                  70                  75                  80  


Ser Tyr Ile Arg Asp Ser Ala Ala Ala Val Val Val Tyr Asp Ile Thr 
                85                  90                  95      


Asn Val Asn Ser Phe Gln Gln Thr Thr Lys Trp Ile Asp Asp Val Arg 
            100                 105                 110         


Thr Glu Arg Gly Ser Asp Val Ile Ile Met Leu Val Gly Asn Lys Thr 
        115                 120                 125             


Asp Leu Ala Asp Lys Arg Gln Val Ser Ile Glu Glu Gly Glu Arg Lys 
    130                 135                 140                 


Ala Lys Glu Leu Asn Val Met Phe Ile Glu Thr Ser Ala Lys Ala Gly 
145                 150                 155                 160 


Tyr Asn Val Lys Gln Leu Phe Arg Arg Val Ala Ala Ala Leu Pro Gly 
                165                 170                 175     


Met Glu Ser Thr Gln Asp Arg Ser Arg Glu Asp Met Ile Asp Ile Lys 
            180                 185                 190         


Leu Glu Lys Pro Gln Glu Gln Pro Val Ser Glu Gly Gly Cys Ser Cys 
        195                 200                 205             


<210>  3368
<211>  493
<212>  PRT
<213>  homo sapiens

<400>  3368

Met Ala Leu Phe Gly Ala Leu Phe Leu Ala Leu Leu Ala Gly Ala His 
1               5                   10                  15      


Ala Glu Phe Pro Gly Cys Lys Ile Arg Val Thr Ser Lys Ala Leu Glu 
            20                  25                  30          


Leu Val Lys Gln Glu Gly Leu Arg Phe Leu Glu Gln Glu Leu Glu Thr 
        35                  40                  45              


Ile Thr Ile Pro Asp Leu Arg Gly Lys Glu Gly His Phe Tyr Tyr Asn 
    50                  55                  60                  


Ile Ser Glu Val Lys Val Thr Glu Leu Gln Leu Thr Ser Ser Glu Leu 
65                  70                  75                  80  


Asp Phe Gln Pro Gln Gln Glu Leu Met Leu Gln Ile Thr Asn Ala Ser 
                85                  90                  95      


Leu Gly Leu Arg Phe Arg Arg Gln Leu Leu Tyr Trp Phe Phe Tyr Asp 
            100                 105                 110         


Gly Gly Tyr Ile Asn Ala Ser Ala Glu Gly Val Ser Ile Arg Thr Gly 
        115                 120                 125             


Leu Glu Leu Ser Arg Asp Pro Ala Gly Arg Met Lys Val Ser Asn Val 
    130                 135                 140                 


Ser Cys Gln Ala Ser Val Ser Arg Met His Ala Ala Phe Gly Gly Thr 
145                 150                 155                 160 


Phe Lys Lys Val Tyr Asp Phe Leu Ser Thr Phe Ile Thr Ser Gly Met 
                165                 170                 175     


Arg Phe Leu Leu Asn Gln Gln Ile Cys Pro Val Leu Tyr His Ala Gly 
            180                 185                 190         


Thr Val Leu Leu Asn Ser Leu Leu Asp Thr Val Pro Val Arg Ser Ser 
        195                 200                 205             


Val Asp Glu Leu Val Gly Ile Asp Tyr Ser Leu Met Lys Asp Pro Val 
    210                 215                 220                 


Ala Ser Thr Ser Asn Leu Asp Met Asp Phe Arg Gly Ala Phe Phe Pro 
225                 230                 235                 240 


Leu Thr Glu Arg Asn Trp Ser Leu Pro Asn Arg Ala Val Glu Pro Gln 
                245                 250                 255     


Leu Gln Glu Glu Glu Arg Met Val Tyr Val Ala Phe Ser Glu Phe Phe 
            260                 265                 270         


Phe Asp Ser Ala Met Glu Ser Tyr Phe Arg Ala Gly Ala Leu Gln Leu 
        275                 280                 285             


Leu Leu Val Gly Asp Lys Val Pro His Asp Leu Asp Met Leu Leu Arg 
    290                 295                 300                 


Ala Thr Tyr Phe Gly Ser Ile Val Leu Leu Ser Pro Ala Val Ile Asp 
305                 310                 315                 320 


Ser Pro Leu Lys Leu Glu Leu Arg Val Leu Ala Pro Pro Arg Cys Thr 
                325                 330                 335     


Ile Lys Pro Ser Gly Thr Thr Ile Ser Val Thr Ala Ser Val Thr Ile 
            340                 345                 350         


Ala Leu Val Pro Pro Asp Gln Pro Glu Val Gln Leu Ser Ser Met Thr 
        355                 360                 365             


Met Asp Ala Arg Leu Ser Ala Lys Met Ala Leu Arg Gly Lys Ala Leu 
    370                 375                 380                 


Arg Thr Gln Leu Asp Leu Arg Arg Phe Arg Ile Tyr Ser Asn His Ser 
385                 390                 395                 400 


Ala Leu Glu Ser Leu Ala Leu Ile Pro Leu Gln Ala Pro Leu Lys Thr 
                405                 410                 415     


Met Leu Gln Ile Gly Val Met Pro Met Leu Asn Glu Arg Thr Trp Arg 
            420                 425                 430         


Gly Val Gln Ile Pro Leu Pro Glu Gly Ile Asn Phe Val His Glu Val 
        435                 440                 445             


Val Thr Asn His Ala Gly Phe Leu Thr Ile Gly Ala Asp Leu His Phe 
    450                 455                 460                 


Ala Lys Gly Leu Arg Glu Val Ile Glu Lys Asn Arg Pro Ala Asp Val 
465                 470                 475                 480 


Arg Ala Ser Thr Ala Pro Thr Pro Ser Thr Ala Ala Val 
                485                 490             


<210>  3369
<211>  371
<212>  PRT
<213>  homo sapiens

<400>  3369

Met Glu Leu Glu Leu Asp Ala Gly Asp Gln Asp Leu Leu Ala Phe Leu 
1               5                   10                  15      


Leu Glu Glu Ser Gly Asp Leu Gly Thr Ala Pro Asp Glu Ala Val Arg 
            20                  25                  30          


Ala Pro Leu Asp Trp Ala Leu Pro Leu Ser Glu Val Pro Ser Asp Trp 
        35                  40                  45              


Glu Val Asp Asp Leu Leu Cys Ser Leu Leu Ser Pro Pro Ala Ser Leu 
    50                  55                  60                  


Asn Ile Leu Ser Ser Ser Asn Pro Cys Leu Val His His Asp His Thr 
65                  70                  75                  80  


Tyr Ser Leu Pro Arg Glu Thr Val Ser Met Asp Leu Glu Ser Glu Ser 
                85                  90                  95      


Cys Arg Lys Glu Gly Thr Gln Met Thr Pro Gln His Met Glu Glu Leu 
            100                 105                 110         


Ala Glu Gln Glu Ile Ala Arg Leu Val Leu Thr Asp Glu Glu Lys Ser 
        115                 120                 125             


Leu Leu Glu Lys Glu Gly Leu Ile Leu Pro Glu Thr Leu Pro Leu Thr 
    130                 135                 140                 


Lys Thr Glu Glu Gln Ile Leu Lys Arg Val Arg Arg Lys Ile Arg Asn 
145                 150                 155                 160 


Lys Arg Ser Ala Gln Glu Ser Arg Arg Lys Lys Lys Val Tyr Val Gly 
                165                 170                 175     


Gly Leu Glu Ser Arg Val Leu Lys Tyr Thr Ala Gln Asn Met Glu Leu 
            180                 185                 190         


Gln Asn Lys Val Gln Leu Leu Glu Glu Gln Asn Leu Ser Leu Leu Asp 
        195                 200                 205             


Gln Leu Arg Lys Leu Gln Ala Met Val Ile Glu Ile Ser Asn Lys Thr 
    210                 215                 220                 


Ser Ser Ser Ser Thr Cys Ile Leu Val Leu Leu Val Ser Phe Cys Leu 
225                 230                 235                 240 


Leu Leu Val Pro Ala Met Tyr Ser Ser Asp Thr Arg Gly Ser Leu Pro 
                245                 250                 255     


Ala Glu His Gly Val Leu Ser Arg Gln Leu Arg Ala Leu Pro Ser Glu 
            260                 265                 270         


Asp Pro Tyr Gln Leu Glu Leu Pro Ala Leu Gln Ser Glu Val Pro Lys 
        275                 280                 285             


Asp Ser Thr His Gln Trp Leu Asp Gly Ser Asp Cys Val Leu Gln Ala 
    290                 295                 300                 


Pro Gly Asn Thr Ser Cys Leu Leu His Tyr Met Pro Gln Ala Pro Ser 
305                 310                 315                 320 


Ala Glu Pro Pro Leu Glu Trp Pro Phe Pro Asp Leu Phe Ser Glu Pro 
                325                 330                 335     


Leu Cys Arg Gly Pro Ile Leu Pro Leu Gln Ala Asn Leu Thr Arg Lys 
            340                 345                 350         


Gly Gly Trp Leu Pro Thr Gly Ser Pro Ser Val Ile Leu Gln Asp Arg 
        355                 360                 365             


Tyr Ser Gly 
    370     


<210>  3370
<211>  673
<212>  PRT
<213>  homo sapiens

<400>  3370

Met Asp Leu Thr Lys Met Gly Met Ile Gln Leu Gln Asn Pro Ser His 
1               5                   10                  15      


Pro Thr Gly Leu Leu Cys Lys Ala Asn Gln Met Arg Leu Ala Gly Thr 
            20                  25                  30          


Leu Cys Asp Val Val Ile Met Val Asp Ser Gln Glu Phe His Ala His 
        35                  40                  45              


Arg Thr Val Leu Ala Cys Thr Ser Lys Met Phe Glu Ile Leu Phe His 
    50                  55                  60                  


Arg Asn Ser Gln His Tyr Thr Leu Asp Phe Leu Ser Pro Lys Thr Phe 
65                  70                  75                  80  


Gln Gln Ile Leu Glu Tyr Ala Tyr Thr Ala Thr Leu Gln Ala Lys Ala 
                85                  90                  95      


Glu Asp Leu Asp Asp Leu Leu Tyr Ala Ala Glu Ile Leu Glu Ile Glu 
            100                 105                 110         


Tyr Leu Glu Glu Gln Cys Leu Lys Met Leu Glu Thr Ile Gln Ala Ser 
        115                 120                 125             


Asp Asp Asn Asp Thr Glu Ala Thr Met Ala Asp Gly Gly Ala Glu Glu 
    130                 135                 140                 


Glu Glu Asp Arg Lys Ala Arg Tyr Leu Lys Asn Ile Phe Ile Ser Lys 
145                 150                 155                 160 


His Ser Ser Glu Glu Ser Gly Tyr Ala Ser Val Ala Gly Gln Ser Leu 
                165                 170                 175     


Pro Gly Pro Met Val Asp Gln Ser Pro Ser Val Ser Thr Ser Phe Gly 
            180                 185                 190         


Leu Ser Ala Met Ser Pro Thr Lys Ala Ala Val Asp Ser Leu Met Thr 
        195                 200                 205             


Ile Gly Gln Ser Leu Leu Gln Gly Thr Leu Gln Pro Pro Ala Gly Pro 
    210                 215                 220                 


Glu Glu Pro Thr Leu Ala Gly Gly Gly Arg His Pro Gly Val Ala Glu 
225                 230                 235                 240 


Val Lys Thr Glu Met Met Gln Val Asp Glu Val Pro Ser Gln Asp Ser 
                245                 250                 255     


Pro Gly Ala Ala Glu Ser Ser Ile Ser Gly Gly Met Gly Asp Lys Val 
            260                 265                 270         


Glu Glu Arg Gly Lys Glu Gly Pro Gly Thr Pro Thr Arg Ser Ser Val 
        275                 280                 285             


Ile Thr Ser Ala Arg Glu Leu His Tyr Gly Arg Glu Glu Ser Ala Glu 
    290                 295                 300                 


Gln Val Pro Pro Pro Ala Glu Ala Gly Gln Ala Pro Thr Gly Arg Pro 
305                 310                 315                 320 


Glu His Pro Ala Pro Pro Pro Glu Lys His Leu Gly Ile Tyr Ser Val 
                325                 330                 335     


Leu Pro Asn His Lys Ala Asp Ala Val Leu Ser Met Pro Ser Ser Val 
            340                 345                 350         


Thr Ser Gly Leu His Val Gln Pro Ala Leu Ala Val Ser Met Asp Phe 
        355                 360                 365             


Ser Thr Tyr Gly Gly Leu Leu Pro Gln Gly Phe Ile Gln Arg Glu Leu 
    370                 375                 380                 


Phe Ser Lys Leu Gly Glu Leu Ala Val Gly Met Lys Ser Glu Ser Arg 
385                 390                 395                 400 


Thr Ile Gly Glu Gln Cys Ser Val Cys Gly Val Glu Leu Pro Asp Asn 
                405                 410                 415     


Glu Ala Val Glu Gln His Arg Lys Leu His Ser Gly Met Lys Thr Tyr 
            420                 425                 430         


Gly Cys Glu Leu Cys Gly Lys Arg Phe Leu Asp Ser Leu Arg Leu Arg 
        435                 440                 445             


Met His Leu Leu Ala His Ser Ala Gly Ala Lys Ala Phe Val Cys Asp 
    450                 455                 460                 


Gln Cys Gly Ala Gln Phe Ser Lys Glu Asp Ala Leu Glu Thr His Arg 
465                 470                 475                 480 


Gln Thr His Thr Gly Thr Asp Met Ala Val Phe Cys Leu Leu Cys Gly 
                485                 490                 495     


Lys Arg Phe Gln Ala Gln Ser Ala Leu Gln Gln His Met Glu Val His 
            500                 505                 510         


Ala Gly Val Arg Ser Tyr Ile Cys Ser Glu Cys Asn Arg Thr Phe Pro 
        515                 520                 525             


Ser His Thr Ala Leu Lys Arg His Leu Arg Ser His Thr Gly Asp His 
    530                 535                 540                 


Pro Tyr Glu Cys Glu Phe Cys Gly Ser Cys Phe Arg Asp Glu Ser Thr 
545                 550                 555                 560 


Leu Lys Ser His Lys Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys 
                565                 570                 575     


Asn Gly Cys Gly Lys Lys Phe Ser Leu Lys His Gln Leu Glu Thr His 
            580                 585                 590         


Tyr Arg Val His Thr Gly Glu Lys Pro Phe Glu Cys Lys Leu Cys His 
        595                 600                 605             


Gln Arg Ser Arg Asp Tyr Ser Ala Met Ile Lys His Leu Arg Thr His 
    610                 615                 620                 


Asn Gly Ala Ser Pro Tyr Gln Cys Thr Ile Cys Thr Glu Tyr Cys Pro 
625                 630                 635                 640 


Ser Leu Ser Ser Met Gln Lys His Met Lys Gly His Lys Pro Glu Glu 
                645                 650                 655     


Ile Pro Pro Asp Trp Arg Ile Glu Lys Thr Tyr Leu Tyr Leu Cys Tyr 
            660                 665                 670         


Val 
    


<210>  3371
<211>  450
<212>  PRT
<213>  homo sapiens

<400>  3371

Met Pro Thr Val Glu Glu Leu Tyr Arg Asn Tyr Gly Ile Leu Ala Asp 
1               5                   10                  15      


Ala Thr Glu Gln Val Gly Gln Ile Arg Arg Gln Ala Ile Lys Glu Leu 
            20                  25                  30          


Pro Gln Phe Ala Thr Gly Glu Asn Leu Pro Arg Val Ala Asp Ile Leu 
        35                  40                  45              


Thr Gln Leu Leu Gln Thr Asp Asp Ser Ala Glu Phe Asn Leu Val Asn 
    50                  55                  60                  


Asn Ala Leu Leu Ser Ile Phe Lys Met Asp Ala Lys Gly Thr Leu Gly 
65                  70                  75                  80  


Gly Leu Phe Ser Gln Ile Leu Gln Gly Glu Asp Ile Val Arg Glu Arg 
                85                  90                  95      


Ala Ile Lys Phe Leu Ser Thr Lys Leu Lys Thr Leu Pro Asp Glu Val 
            100                 105                 110         


Leu Thr Lys Glu Val Glu Glu Leu Ile Leu Thr Glu Ser Lys Lys Val 
        115                 120                 125             


Leu Glu Asp Val Thr Gly Glu Glu Phe Val Leu Phe Met Lys Ile Leu 
    130                 135                 140                 


Ser Gly Leu Lys Ser Leu Gln Thr Val Ser Gly Arg Gln Gln Leu Val 
145                 150                 155                 160 


Glu Leu Val Ala Glu Gln Ala Asp Leu Glu Gln Thr Phe Asn Pro Ser 
                165                 170                 175     


Asp Pro Asp Cys Val Asp Arg Leu Leu Gln Cys Thr Arg Gln Ala Val 
            180                 185                 190         


Pro Leu Phe Ser Lys Asn Val His Ser Thr Arg Phe Val Thr Tyr Phe 
        195                 200                 205             


Cys Glu Gln Val Leu Pro Asn Leu Gly Thr Leu Thr Thr Pro Val Glu 
    210                 215                 220                 


Gly Leu Asp Ile Gln Leu Glu Val Leu Lys Leu Leu Ala Glu Met Ser 
225                 230                 235                 240 


Ser Phe Cys Gly Asp Met Glu Lys Leu Glu Thr Asn Leu Arg Lys Leu 
                245                 250                 255     


Phe Asp Lys Leu Leu Glu Tyr Met Pro Leu Pro Pro Glu Glu Ala Glu 
            260                 265                 270         


Asn Gly Glu Asn Ala Gly Asn Glu Glu Pro Lys Leu Gln Phe Ser Tyr 
        275                 280                 285             


Val Glu Cys Leu Leu Tyr Ser Phe His Gln Leu Gly Arg Lys Leu Pro 
    290                 295                 300                 


Asp Phe Leu Thr Ala Lys Leu Asn Ala Glu Lys Leu Lys Asp Phe Lys 
305                 310                 315                 320 


Ile Arg Leu Gln Tyr Phe Ala Arg Gly Leu Gln Val Tyr Ile Arg Gln 
                325                 330                 335     


Leu Arg Leu Ala Leu Gln Gly Lys Thr Gly Glu Ala Leu Lys Thr Glu 
            340                 345                 350         


Glu Asn Lys Ile Lys Val Val Ala Leu Lys Ile Thr Asn Asn Ile Asn 
        355                 360                 365             


Val Leu Ile Lys Asp Leu Phe His Ile Pro Pro Ser Tyr Lys Ser Thr 
    370                 375                 380                 


Val Thr Leu Ser Trp Lys Pro Val Gln Lys Val Glu Ile Gly Gln Lys 
385                 390                 395                 400 


Arg Ala Ser Glu Asp Thr Thr Ser Gly Ser Pro Pro Lys Lys Ser Ser 
                405                 410                 415     


Ala Gly Pro Lys Arg Asp Ala Arg Gln Ile Tyr Asn Pro Pro Ser Gly 
            420                 425                 430         


Lys Tyr Ser Ser Asn Leu Gly Asn Phe Asn Tyr Glu Arg Ser Leu Gln 
        435                 440                 445             


Gly Lys 
    450 


<210>  3372
<211>  459
<212>  PRT
<213>  homo sapiens

<400>  3372

Met Val Glu Leu Val Ile Ser Pro Ser Leu Thr Val Asn Ser Asp Cys 
1               5                   10                  15      


Leu Asp Lys Leu Lys Phe Asn Arg Ala Asp Ala Ala Val Trp Thr Leu 
            20                  25                  30          


Ser Asp Arg Gln Gly Ile Thr Lys Ser Ala Pro Leu Arg Val Ser Gln 
        35                  40                  45              


Leu Phe Ser Arg Ser Cys Pro Arg Val Leu Pro Arg Gln Pro Ser Thr 
    50                  55                  60                  


Ala Met Ala Ala Tyr Gly Gln Thr Gln Tyr Ser Ala Gly Ile Gln Gln 
65                  70                  75                  80  


Ala Thr Pro Tyr Thr Ala Tyr Pro Pro Pro Ala Gln Ala Tyr Gly Ile 
                85                  90                  95      


Pro Ser Tyr Ser Ile Lys Thr Glu Asp Ser Leu Asn His Ser Pro Gly 
            100                 105                 110         


Gln Ser Gly Phe Leu Ser Tyr Gly Ser Ser Phe Ser Thr Ser Pro Thr 
        115                 120                 125             


Gly Gln Ser Pro Tyr Thr Tyr Gln Met His Gly Thr Thr Gly Phe Tyr 
    130                 135                 140                 


Gln Gly Gly Asn Gly Leu Gly Asn Ala Ala Gly Phe Gly Ser Val His 
145                 150                 155                 160 


Gln Asp Tyr Pro Ser Tyr Pro Gly Phe Pro Gln Ser Gln Tyr Pro Gln 
                165                 170                 175     


Tyr Tyr Gly Ser Ser Tyr Asn Pro Pro Tyr Val Pro Ala Ser Ser Ile 
            180                 185                 190         


Cys Pro Ser Pro Leu Ser Thr Ser Thr Tyr Val Leu Gln Glu Ala Ser 
        195                 200                 205             


His Asn Val Pro Asn Gln Ser Ser Glu Ser Leu Ala Gly Glu Tyr Asn 
    210                 215                 220                 


Thr His Asn Gly Pro Ser Thr Pro Ala Lys Glu Gly Asp Thr Asp Arg 
225                 230                 235                 240 


Pro His Arg Ala Ser Asp Gly Lys Leu Arg Gly Arg Ser Lys Arg Ser 
                245                 250                 255     


Ser Asp Pro Ser Pro Ala Gly Asp Asn Glu Ile Glu Arg Val Phe Val 
            260                 265                 270         


Trp Asp Leu Asp Glu Thr Ile Ile Ile Phe His Ser Leu Leu Thr Gly 
        275                 280                 285             


Thr Phe Ala Ser Arg Tyr Gly Lys Asp Thr Thr Thr Ser Val Arg Ile 
    290                 295                 300                 


Gly Leu Met Met Glu Glu Met Ile Phe Asn Leu Ala Asp Thr His Leu 
305                 310                 315                 320 


Phe Phe Asn Asp Leu Glu Asp Cys Asp Gln Ile His Val Asp Asp Val 
                325                 330                 335     


Ser Ser Asp Asp Asn Gly Gln Asp Leu Ser Thr Tyr Asn Phe Ser Ala 
            340                 345                 350         


Asp Gly Phe His Ser Ser Ala Pro Gly Ala Asn Leu Cys Leu Gly Ser 
        355                 360                 365             


Gly Val His Gly Gly Val Asp Trp Met Arg Lys Leu Ala Phe Arg Tyr 
    370                 375                 380                 


Arg Arg Val Lys Glu Met Tyr Asn Thr Tyr Lys Asn Asn Val Gly Gly 
385                 390                 395                 400 


Lys Glu Ser Cys Phe Glu Arg Ile Met Gln Arg Phe Gly Arg Lys Ala 
                405                 410                 415     


Val Tyr Val Val Ile Gly Asp Gly Val Glu Glu Glu Gln Gly Ala Lys 
            420                 425                 430         


Lys His Asn Met Pro Phe Trp Arg Ile Ser Cys His Ala Asp Leu Glu 
        435                 440                 445             


Ala Leu Arg His Ala Leu Glu Leu Glu Tyr Leu 
    450                 455                 


<210>  3373
<211>  1070
<212>  PRT
<213>  homo sapiens

<400>  3373

Met Thr Ser Pro Ala Lys Phe Lys Lys Asp Lys Glu Ile Ile Ala Glu 
1               5                   10                  15      


Tyr Asp Thr Gln Val Lys Glu Ile Arg Ala Gln Leu Thr Glu Gln Met 
            20                  25                  30          


Lys Cys Leu Asp Gln Gln Cys Glu Leu Arg Val Gln Leu Leu Gln Asp 
        35                  40                  45              


Leu Gln Asp Phe Phe Arg Lys Lys Ala Glu Ile Glu Met Asp Tyr Ser 
    50                  55                  60                  


Arg Asn Leu Glu Lys Leu Ala Glu Arg Phe Leu Ala Lys Thr Arg Ser 
65                  70                  75                  80  


Thr Lys Asp Gln Gln Phe Lys Lys Asp Gln Asn Val Leu Ser Pro Val 
                85                  90                  95      


Asn Cys Trp Asn Leu Leu Leu Asn Gln Val Lys Arg Glu Ser Arg Asp 
            100                 105                 110         


His Thr Thr Leu Ser Asp Ile Tyr Leu Asn Asn Ile Ile Pro Arg Phe 
        115                 120                 125             


Val Gln Val Ser Glu Asp Ser Gly Arg Leu Phe Lys Lys Ser Lys Glu 
    130                 135                 140                 


Val Gly Gln Gln Leu Gln Asp Asp Leu Met Lys Val Leu Asn Glu Leu 
145                 150                 155                 160 


Tyr Ser Val Met Lys Thr Tyr His Met Tyr Asn Ala Asp Ser Ile Ser 
                165                 170                 175     


Ala Gln Ser Lys Leu Lys Glu Ala Glu Lys Gln Glu Glu Lys Gln Ile 
            180                 185                 190         


Gly Lys Ser Val Lys Gln Glu Asp Arg Gln Thr Pro Arg Ser Pro Asp 
        195                 200                 205             


Ser Thr Ala Asn Val Arg Ile Glu Glu Lys His Val Arg Arg Ser Ser 
    210                 215                 220                 


Val Lys Lys Ile Glu Lys Met Lys Glu Lys Arg Gln Ala Lys Tyr Thr 
225                 230                 235                 240 


Glu Asn Lys Leu Lys Ala Ile Lys Ala Arg Asn Glu Tyr Leu Leu Ala 
                245                 250                 255     


Leu Glu Ala Thr Asn Ala Ser Val Phe Lys Tyr Tyr Ile His Asp Leu 
            260                 265                 270         


Ser Asp Leu Ile Asp Cys Cys Asp Leu Gly Tyr His Ala Ser Leu Asn 
        275                 280                 285             


Arg Ala Leu Arg Thr Phe Leu Ser Ala Glu Leu Asn Leu Glu Gln Ser 
    290                 295                 300                 


Lys His Glu Gly Leu Asp Ala Ile Glu Asn Ala Val Glu Asn Leu Asp 
305                 310                 315                 320 


Ala Thr Ser Asp Lys Gln Arg Leu Met Glu Met Tyr Asn Asn Val Phe 
                325                 330                 335     


Cys Pro Pro Met Lys Phe Glu Phe Gln Pro His Met Gly Asp Met Ala 
            340                 345                 350         


Ser Gln Leu Cys Ala Gln Gln Pro Val Gln Ser Glu Leu Val Gln Arg 
        355                 360                 365             


Cys Gln Gln Leu Gln Ser Arg Leu Ser Thr Leu Lys Ile Glu Asn Glu 
    370                 375                 380                 


Glu Val Lys Lys Thr Met Glu Ala Thr Leu Gln Thr Ile Gln Asp Ile 
385                 390                 395                 400 


Val Thr Val Glu Asp Phe Asp Val Ser Asp Cys Phe Gln Tyr Ser Asn 
                405                 410                 415     


Ser Met Glu Ser Val Lys Ser Thr Val Ser Glu Thr Phe Met Ser Lys 
            420                 425                 430         


Pro Ser Ile Ala Lys Arg Arg Ala Asn Gln Gln Glu Thr Glu Gln Phe 
        435                 440                 445             


Tyr Phe Thr Lys Met Lys Glu Tyr Leu Glu Gly Arg Asn Leu Ile Thr 
    450                 455                 460                 


Lys Leu Gln Ala Lys His Asp Leu Leu Gln Lys Thr Leu Gly Glu Ser 
465                 470                 475                 480 


Gln Arg Thr Asp Cys Ser Leu Ala Arg Arg Ser Ser Thr Val Arg Lys 
                485                 490                 495     


Gln Asp Ser Ser Gln Ala Ile Pro Leu Val Val Glu Ser Cys Ile Arg 
            500                 505                 510         


Phe Ile Ser Arg His Gly Leu Gln His Glu Gly Ile Phe Arg Val Ser 
        515                 520                 525             


Gly Ser Gln Val Glu Val Asn Asp Ile Lys Asn Ala Phe Glu Arg Gly 
    530                 535                 540                 


Glu Asp Pro Leu Ala Gly Asp Gln Asn Asp His Asp Met Asp Ser Ile 
545                 550                 555                 560 


Ala Gly Val Leu Lys Leu Tyr Phe Arg Gly Leu Glu His Pro Leu Phe 
                565                 570                 575     


Pro Lys Asp Ile Phe His Asp Leu Met Ala Cys Val Thr Met Asp Asn 
            580                 585                 590         


Leu Gln Glu Arg Ala Leu His Ile Arg Lys Val Leu Leu Val Leu Pro 
        595                 600                 605             


Lys Thr Thr Leu Ile Ile Met Arg Tyr Leu Phe Ala Phe Leu Asn His 
    610                 615                 620                 


Leu Ser Gln Phe Ser Glu Glu Asn Met Met Asp Pro Tyr Asn Leu Ala 
625                 630                 635                 640 


Ile Cys Phe Gly Pro Ser Leu Met Ser Val Pro Glu Gly His Asp Gln 
                645                 650                 655     


Val Ser Cys Gln Ala His Val Asn Glu Leu Ile Lys Thr Ile Ile Ile 
            660                 665                 670         


Gln His Glu Asn Ile Phe Pro Ser Pro Arg Glu Leu Glu Gly Pro Val 
        675                 680                 685             


Tyr Ser Arg Gly Gly Ser Met Glu Asp Tyr Cys Asp Ser Pro His Gly 
    690                 695                 700                 


Glu Thr Thr Ser Val Glu Asp Ser Thr Gln Asp Val Thr Ala Glu His 
705                 710                 715                 720 


His Thr Ser Asp Asp Glu Cys Glu Pro Ile Glu Ala Ile Ala Lys Phe 
                725                 730                 735     


Asp Tyr Val Gly Arg Thr Ala Arg Glu Leu Ser Phe Lys Lys Gly Ala 
            740                 745                 750         


Ser Leu Leu Leu Tyr Gln Arg Ala Ser Asp Asp Trp Trp Glu Gly Arg 
        755                 760                 765             


His Asn Gly Ile Asp Gly Leu Ile Pro His Gln Tyr Ile Val Val Gln 
    770                 775                 780                 


Asp Thr Glu Asp Gly Val Val Glu Arg Ser Ser Pro Lys Ser Glu Ile 
785                 790                 795                 800 


Glu Val Ile Ser Glu Pro Pro Glu Glu Lys Val Thr Ala Arg Ala Gly 
                805                 810                 815     


Ala Ser Cys Pro Ser Gly Gly His Val Ala Asp Ile Tyr Leu Ala Asn 
            820                 825                 830         


Ile Asn Lys Gln Arg Lys Arg Pro Glu Ser Gly Ser Ile Arg Lys Thr 
        835                 840                 845             


Phe Arg Ser Asp Ser His Gly Leu Ser Ser Ser Leu Thr Asp Ser Ser 
    850                 855                 860                 


Ser Pro Gly Val Gly Ala Ser Cys Arg Pro Ser Ser Gln Pro Ile Met 
865                 870                 875                 880 


Ser Gln Ser Leu Pro Lys Glu Gly Pro Asp Lys Cys Ser Ile Ser Gly 
                885                 890                 895     


His Gly Ser Leu Asn Ser Ile Ser Arg His Ser Ser Leu Lys Asn Arg 
            900                 905                 910         


Leu Asp Ser Pro Gln Ile Arg Lys Thr Ala Thr Ala Gly Arg Ser Lys 
        915                 920                 925             


Ser Phe Asn Asn His Arg Pro Met Asp Pro Glu Val Ile Ala Gln Asp 
    930                 935                 940                 


Ile Glu Ala Thr Met Asn Ser Ala Leu Asn Glu Leu Arg Glu Leu Glu 
945                 950                 955                 960 


Arg Gln Ser Ser Val Lys His Thr Pro Asp Val Val Leu Asp Thr Leu 
                965                 970                 975     


Glu Pro Leu Lys Thr Ser Pro Val Val Ala Pro Thr Ser Glu Pro Ser 
            980                 985                 990         


Ser Pro Leu His Thr Gln Leu Leu  Lys Asp Pro Glu Pro  Ala Phe Gln 
        995                 1000                 1005             


Arg Ser  Ala Ser Thr Ala Gly  Asp Ile Ala Cys Ala  Phe Arg Pro 
    1010                 1015                 1020             


Val Lys  Ser Val Lys Met Ala  Ala Pro Val Lys Pro  Pro Ala Thr 
    1025                 1030                 1035             


Arg Pro  Lys Pro Thr Val Phe  Pro Lys Thr Asn Ala  Thr Ser Pro 
    1040                 1045                 1050             


Gly Val  Asn Ser Ser Thr Ser  Pro Gln Ser Thr Asp  Lys Ser Cys 
    1055                 1060                 1065             


Thr Val  
    1070 


<210>  3374
<211>  1256
<212>  PRT
<213>  homo sapiens

<400>  3374

Met Asp Arg Pro Leu Ser Ser Ser Ala Glu Ala Glu Glu Glu Leu Glu 
1               5                   10                  15      


Trp Gln Val Ala Ser Arg Arg Arg Lys Ala Trp Ala Lys Cys Arg Ser 
            20                  25                  30          


Ser Trp Gln Ala Ser Glu Thr Glu Asp Leu Ser Thr Glu Ala Thr Thr 
        35                  40                  45              


Gln Asp Glu Glu Glu Asp Glu Glu Glu Asp Leu Pro Gly Ala Gln Leu 
    50                  55                  60                  


Pro Ala Ala Gly Gly Arg Gly Asn Val Pro Asn Glu Lys Ile Ala Ile 
65                  70                  75                  80  


Trp Leu Lys Asp Cys Arg Thr Pro Leu Gly Ala Ser Leu Asp Glu Gln 
                85                  90                  95      


Ser Ser Ser Thr Leu Lys Gly Val Leu Val Arg Asn Gly Gly Ser Phe 
            100                 105                 110         


Glu Asp Asp Leu Ser Leu Gly Ala Glu Ala Asn His Leu His Glu Ser 
        115                 120                 125             


Asp Ala Gln Ile Glu Asn Cys Asn Asn Ile Leu Ala Lys Glu Arg Arg 
    130                 135                 140                 


Leu Gln Phe His Gln Lys Gly Arg Ser Met Asn Ser Thr Gly Ser Gly 
145                 150                 155                 160 


Lys Ser Ser Gly Thr Val Ser Ser Val Ser Glu Leu Leu Glu Leu Tyr 
                165                 170                 175     


Glu Glu Asp Pro Glu Glu Ile Leu Tyr Asn Leu Gly Phe Gly Arg Asp 
            180                 185                 190         


Glu Pro Asp Ile Ala Ser Lys Ile Pro Ser Arg Phe Phe Asn Ser Ser 
        195                 200                 205             


Ser Phe Ala Lys Gly Ile Asp Ile Lys Val Phe Leu Ser Ala Gln Met 
    210                 215                 220                 


Gln Arg Met Glu Val Glu Asn Pro Asn Tyr Ala Leu Thr Ser Arg Phe 
225                 230                 235                 240 


Arg Gln Ile Glu Val Leu Thr Thr Val Ala Asn Ala Phe Ser Ser Leu 
                245                 250                 255     


Tyr Ser Gln Val Ser Gly Thr Pro Leu Gln Arg Ile Gly Ser Met Ser 
            260                 265                 270         


Ser Val Thr Ser Asn Lys Glu Thr Asp Pro Pro Pro Pro Leu Thr Arg 
        275                 280                 285             


Ser Asn Thr Ala Asn Arg Leu Met Lys Thr Leu Ser Lys Leu Asn Leu 
    290                 295                 300                 


Cys Val Asp Lys Thr Glu Lys Gly Glu Ser Ser Ser Pro Ser Pro Ser 
305                 310                 315                 320 


Ala Glu Lys Gly Lys Ile Leu Asn Val Ser Val Ile Glu Glu Ser Gly 
                325                 330                 335     


Asn Lys Asn Asp Gln Lys Ser Gln Lys Ile Met Lys Lys Lys Glu Ser 
            340                 345                 350         


Ser Ser Met Leu Ala Thr Val Lys Glu Glu Val Ser Gly Ser Ser Ala 
        355                 360                 365             


Ala Val Thr Glu Asn Ala Asp Ser Asp Arg Ile Ser Asp Glu Ala Asn 
    370                 375                 380                 


Ser Asn Phe Asn Gln Gly Thr Glu Asn Glu Gln Ser Lys Glu Thr Gln 
385                 390                 395                 400 


Ser His Glu Ser Lys Leu Gly Glu Glu Ser Gly Ile Val Glu Ser Lys 
                405                 410                 415     


Leu Asp Ser Asp Phe Asn Ile Ser Ser His Ser Glu Leu Glu Asn Ser 
            420                 425                 430         


Ser Glu Leu Lys Ser Val His Ile Ser Thr Pro Glu Lys Glu Pro Cys 
        435                 440                 445             


Ala Pro Leu Thr Ile Pro Ser Ile Arg Asn Ile Met Thr Gln Gln Lys 
    450                 455                 460                 


Asp Ser Phe Glu Met Glu Glu Val Gln Ser Thr Glu Gly Glu Ala Pro 
465                 470                 475                 480 


His Val Pro Ala Thr Tyr Gln Leu Gly Leu Thr Lys Ser Lys Arg Asp 
                485                 490                 495     


His Leu Leu Arg Thr Ala Ser Gln His Ser Asp Ser Ser Gly Phe Ala 
            500                 505                 510         


Glu Asp Ser Thr Asp Cys Leu Ser Leu Asn His Leu Gln Val Gln Glu 
        515                 520                 525             


Ser Leu Gln Ala Met Gly Ser Ser Ala Asp Ser Cys Asp Ser Glu Thr 
    530                 535                 540                 


Thr Val Thr Ser Leu Gly Glu Asp Leu Ala Thr Pro Thr Ala Gln Asp 
545                 550                 555                 560 


Gln Pro Tyr Phe Asn Glu Ser Glu Glu Glu Ser Leu Val Pro Leu Gln 
                565                 570                 575     


Lys Gly Leu Glu Lys Ala Ala Ala Val Ala Asp Lys Arg Lys Ser Gly 
            580                 585                 590         


Ser Gln Asp Phe Pro Gln Cys Asn Thr Ile Glu Asn Thr Gly Thr Lys 
        595                 600                 605             


Gln Ser Thr Cys Ser Pro Gly Asp His Ile Ile Glu Ile Thr Glu Val 
    610                 615                 620                 


Glu Glu Asp Leu Phe Pro Ala Glu Thr Val Glu Leu Leu Arg Glu Ala 
625                 630                 635                 640 


Ser Ala Glu Ser Asp Val Gly Lys Ser Ser Glu Ser Glu Phe Thr Gln 
                645                 650                 655     


Tyr Thr Thr His His Ile Leu Lys Ser Leu Ala Ser Ile Glu Ala Lys 
            660                 665                 670         


Cys Ser Asp Met Ser Ser Glu Asn Thr Thr Gly Pro Pro Ser Ser Met 
        675                 680                 685             


Asp Arg Val Asn Thr Ala Leu Gln Arg Ala Gln Met Lys Val Cys Ser 
    690                 695                 700                 


Leu Ser Asn Gln Arg Met Gly Arg Ser Leu Leu Lys Ser Lys Asp Leu 
705                 710                 715                 720 


Leu Lys Gln Arg Tyr Leu Phe Ala Lys Ala Gly Tyr Pro Leu Arg Arg 
                725                 730                 735     


Ser Gln Ser Leu Pro Thr Thr Leu Leu Ser Pro Val Arg Val Val Ser 
            740                 745                 750         


Ser Val Asn Val Arg Leu Ser Pro Gly Lys Glu Thr Arg Cys Ser Pro 
        755                 760                 765             


Pro Ser Phe Thr Tyr Lys Tyr Thr Pro Glu Glu Glu Gln Glu Leu Glu 
    770                 775                 780                 


Lys Arg Val Met Glu His Asp Gly Gln Ser Leu Val Lys Ser Thr Ile 
785                 790                 795                 800 


Phe Ile Ser Pro Ser Ser Val Lys Lys Glu Glu Ala Pro Gln Ser Glu 
                805                 810                 815     


Ala Pro Arg Val Glu Glu Cys His His Gly Arg Thr Pro Thr Cys Ser 
            820                 825                 830         


Arg Leu Ala Pro Pro Pro Met Ser Gln Ser Thr Cys Ser Leu His Ser 
        835                 840                 845             


Ile His Ser Glu Trp Gln Glu Arg Pro Leu Cys Glu His Thr Arg Thr 
    850                 855                 860                 


Leu Ser Thr His Ser Val Pro Asn Ile Ser Gly Ala Thr Cys Ser Ala 
865                 870                 875                 880 


Phe Ala Ser Pro Phe Gly Cys Pro Tyr Ser His Arg His Ala Thr Tyr 
                885                 890                 895     


Pro Tyr Arg Val Cys Ser Val Asn Pro Pro Ser Ala Ile Glu Met Gln 
            900                 905                 910         


Leu Arg Arg Val Leu His Asp Ile Arg Asn Ser Leu Gln Asn Leu Ser 
        915                 920                 925             


Gln Tyr Pro Met Met Arg Gly Pro Asp Pro Ala Ala Ala Pro Tyr Ser 
    930                 935                 940                 


Thr Gln Lys Ser Ser Val Leu Pro Leu Tyr Glu Asn Thr Phe Gln Glu 
945                 950                 955                 960 


Leu Gln Val Met Arg Arg Ser Leu Asn Leu Phe Arg Thr Gln Met Met 
                965                 970                 975     


Asp Leu Glu Leu Ala Met Leu Arg Gln Gln Thr Met Val Tyr His His 
            980                 985                 990         


Met Thr Glu Glu Glu Arg Phe Glu  Val Asp Gln Leu Gln  Gly Leu Arg 
        995                 1000                 1005             


Asn Ser  Val Arg Met Glu Leu  Gln Asp Leu Glu Leu  Gln Leu Glu 
    1010                 1015                 1020             


Glu Arg  Leu Leu Gly Leu Glu  Glu Gln Leu Arg Ala  Val Arg Met 
    1025                 1030                 1035             


Pro Ser  Pro Phe Arg Ser Ser  Ala Leu Met Gly Met  Cys Gly Ser 
    1040                 1045                 1050             


Arg Ser  Ala Asp Asn Leu Ser  Cys Pro Ser Pro Leu  Asn Val Met 
    1055                 1060                 1065             


Glu Pro  Val Thr Glu Leu Met  Gln Glu Gln Ser Tyr  Leu Lys Ser 
    1070                 1075                 1080             


Glu Leu  Gly Leu Gly Leu Gly  Glu Met Gly Phe Glu  Ile Pro Pro 
    1085                 1090                 1095             


Gly Glu  Ser Ser Glu Ser Val  Phe Ser Gln Ala Thr  Ser Glu Ser 
    1100                 1105                 1110             


Ser Ser  Val Cys Ser Gly Pro  Ser His Ala Asn Arg  Arg Thr Gly 
    1115                 1120                 1125             


Val Pro  Ser Thr Ala Ser Val  Gly Lys Ser Lys Thr  Pro Leu Val 
    1130                 1135                 1140             


Ala Arg  Lys Lys Val Phe Arg  Ala Ser Val Ala Leu  Thr Pro Thr 
    1145                 1150                 1155             


Ala Pro  Ser Arg Thr Gly Ser  Val Gln Thr Pro Pro  Asp Leu Glu 
    1160                 1165                 1170             


Ser Ser  Glu Glu Val Asp Ala  Ala Glu Gly Ala Pro  Glu Val Val 
    1175                 1180                 1185             


Gly Pro  Lys Ser Glu Val Glu  Glu Gly His Gly Lys  Leu Pro Ser 
    1190                 1195                 1200             


Met Pro  Ala Ala Glu Glu Met  His Lys Asn Val Glu  Gln Asp Glu 
    1205                 1210                 1215             


Leu Gln  Gln Val Ile Arg Glu  Val Gly Met Asp Pro  Ile Ser Cys 
    1220                 1225                 1230             


Val Ile  Leu Glu Leu Ser Met  Ile Cys Thr Gly Gly  Gly Val Ile 
    1235                 1240                 1245             


Cys Ala  Leu Glu Asp Thr Cys  Cys 
    1250                 1255     


<210>  3375
<211>  1259
<212>  PRT
<213>  homo sapiens

<400>  3375

Met Asp Arg Pro Leu Ser Ser Ser Ala Glu Ala Glu Glu Glu Leu Glu 
1               5                   10                  15      


Trp Gln Val Ala Ser Arg Arg Arg Lys Ala Trp Ala Lys Cys Arg Ser 
            20                  25                  30          


Ser Trp Gln Ala Ser Glu Thr Glu Asp Leu Ser Thr Glu Ala Thr Thr 
        35                  40                  45              


Gln Asp Glu Glu Glu Asp Glu Glu Glu Asp Leu Pro Gly Ala Gln Leu 
    50                  55                  60                  


Pro Ala Ala Gly Gly Arg Gly Asn Val Pro Asn Glu Lys Ile Ala Ile 
65                  70                  75                  80  


Trp Leu Lys Asp Cys Arg Thr Pro Leu Gly Ala Ser Leu Asp Glu Gln 
                85                  90                  95      


Ser Ser Ser Thr Leu Lys Gly Val Leu Val Arg Asn Gly Gly Ser Phe 
            100                 105                 110         


Glu Asp Asp Leu Ser Leu Gly Ala Glu Ala Asn His Leu His Glu Ser 
        115                 120                 125             


Asp Ala Gln Ile Glu Asn Cys Asn Asn Ile Leu Ala Lys Glu Arg Arg 
    130                 135                 140                 


Leu Gln Phe His Gln Lys Gly Arg Ser Met Asn Ser Thr Gly Ser Gly 
145                 150                 155                 160 


Lys Ser Ser Gly Thr Val Ser Ser Val Ser Glu Leu Leu Glu Leu Tyr 
                165                 170                 175     


Glu Glu Asp Pro Glu Glu Ile Leu Tyr Asn Leu Gly Phe Gly Arg Asp 
            180                 185                 190         


Glu Pro Asp Ile Ala Ser Lys Ile Pro Ser Arg Phe Phe Asn Ser Ser 
        195                 200                 205             


Ser Phe Ala Lys Gly Ile Asp Ile Lys Val Phe Leu Ser Ala Gln Met 
    210                 215                 220                 


Gln Arg Met Glu Val Glu Asn Pro Asn Tyr Ala Leu Thr Ser Arg Phe 
225                 230                 235                 240 


Arg Gln Ile Glu Val Leu Thr Thr Val Ala Asn Ala Phe Ser Ser Leu 
                245                 250                 255     


Tyr Ser Gln Val Ser Gly Thr Pro Leu Gln Arg Ile Gly Ser Met Ser 
            260                 265                 270         


Ser Val Thr Ser Asn Lys Glu Thr Asp Pro Pro Pro Pro Leu Thr Arg 
        275                 280                 285             


Ser Asn Thr Ala Asn Arg Leu Met Lys Thr Leu Ser Lys Leu Asn Leu 
    290                 295                 300                 


Cys Val Asp Lys Thr Glu Lys Gly Glu Ser Ser Ser Pro Ser Pro Ser 
305                 310                 315                 320 


Ala Glu Lys Gly Lys Ile Leu Asn Val Ser Val Ile Glu Glu Ser Gly 
                325                 330                 335     


Asn Lys Asn Asp Gln Lys Ser Gln Lys Ile Met Lys Lys Lys Glu Ser 
            340                 345                 350         


Ser Ser Met Leu Ala Thr Val Lys Glu Glu Val Ser Gly Ser Ser Ala 
        355                 360                 365             


Ala Val Thr Glu Asn Ala Asp Ser Asp Arg Ile Ser Asp Glu Ala Asn 
    370                 375                 380                 


Ser Asn Phe Asn Gln Gly Thr Glu Asn Glu Gln Ser Lys Glu Thr Gln 
385                 390                 395                 400 


Ser His Glu Ser Lys Leu Gly Glu Glu Ser Gly Ile Val Glu Ser Lys 
                405                 410                 415     


Leu Asp Ser Asp Phe Asn Ile Ser Ser His Ser Glu Leu Glu Asn Ser 
            420                 425                 430         


Ser Glu Leu Lys Ser Val His Ile Ser Thr Pro Glu Lys Glu Pro Cys 
        435                 440                 445             


Ala Pro Leu Thr Ile Pro Ser Ile Arg Asn Ile Met Thr Gln Gln Lys 
    450                 455                 460                 


Asp Ser Phe Glu Met Glu Glu Val Gln Ser Thr Glu Gly Glu Ala Pro 
465                 470                 475                 480 


His Val Pro Ala Thr Tyr Gln Leu Gly Leu Thr Lys Ser Lys Arg Asp 
                485                 490                 495     


His Leu Leu Arg Thr Ala Ser Gln His Ser Asp Ser Ser Gly Phe Ala 
            500                 505                 510         


Glu Asp Ser Thr Asp Cys Leu Ser Leu Asn His Leu Gln Val Gln Glu 
        515                 520                 525             


Ser Leu Gln Ala Met Gly Ser Ser Ala Asp Ser Cys Asp Ser Glu Thr 
    530                 535                 540                 


Thr Val Thr Ser Leu Gly Glu Asp Leu Ala Thr Pro Thr Ala Gln Asp 
545                 550                 555                 560 


Gln Pro Tyr Phe Asn Glu Ser Glu Glu Glu Ser Leu Val Pro Leu Gln 
                565                 570                 575     


Lys Gly Leu Glu Lys Ala Ala Ala Val Ala Asp Lys Arg Lys Ser Gly 
            580                 585                 590         


Ser Gln Asp Phe Pro Gln Cys Asn Thr Ile Glu Asn Thr Gly Thr Lys 
        595                 600                 605             


Gln Ser Thr Cys Ser Pro Gly Asp His Ile Ile Glu Ile Thr Glu Val 
    610                 615                 620                 


Glu Glu Asp Leu Phe Pro Ala Glu Thr Val Glu Leu Leu Arg Glu Ala 
625                 630                 635                 640 


Ser Ala Glu Ser Asp Val Gly Lys Ser Ser Glu Ser Glu Phe Thr Gln 
                645                 650                 655     


Tyr Thr Thr His His Ile Leu Lys Ser Leu Ala Ser Ile Glu Ala Lys 
            660                 665                 670         


Cys Ser Asp Met Ser Ser Glu Asn Thr Thr Gly Pro Pro Ser Ser Met 
        675                 680                 685             


Asp Arg Val Asn Thr Ala Leu Gln Arg Ala Gln Met Lys Val Cys Ser 
    690                 695                 700                 


Leu Ser Asn Gln Arg Met Gly Arg Ser Leu Leu Lys Ser Lys Asp Leu 
705                 710                 715                 720 


Leu Lys Gln Arg Tyr Leu Phe Ala Lys Ala Gly Tyr Pro Leu Arg Arg 
                725                 730                 735     


Ser Gln Ser Leu Pro Thr Thr Leu Leu Ser Pro Val Arg Val Val Ser 
            740                 745                 750         


Ser Val Asn Val Arg Leu Ser Pro Gly Lys Glu Thr Arg Cys Ser Pro 
        755                 760                 765             


Pro Ser Phe Thr Tyr Lys Tyr Thr Pro Glu Glu Glu Gln Glu Leu Glu 
    770                 775                 780                 


Lys Arg Val Met Glu His Asp Gly Gln Ser Leu Val Lys Ser Thr Ile 
785                 790                 795                 800 


Phe Ile Ser Pro Ser Ser Val Lys Lys Glu Glu Ala Pro Gln Ser Glu 
                805                 810                 815     


Ala Pro Arg Val Glu Glu Cys His His Gly Arg Thr Pro Thr Cys Ser 
            820                 825                 830         


Arg Leu Ala Pro Pro Pro Met Ser Gln Ser Thr Cys Ser Leu His Ser 
        835                 840                 845             


Ile His Ser Glu Trp Gln Glu Arg Pro Leu Cys Glu His Thr Arg Thr 
    850                 855                 860                 


Leu Ser Thr His Ser Val Pro Asn Ile Ser Gly Ala Thr Cys Ser Ala 
865                 870                 875                 880 


Phe Ala Ser Pro Phe Gly Cys Pro Tyr Ser His Arg His Ala Thr Tyr 
                885                 890                 895     


Pro Tyr Arg Val Cys Ser Val Asn Pro Pro Ser Ala Ile Glu Met Gln 
            900                 905                 910         


Leu Arg Arg Val Leu His Asp Ile Arg Asn Ser Leu Gln Asn Leu Ser 
        915                 920                 925             


Gln Tyr Pro Met Met Arg Gly Pro Asp Pro Ala Ala Ala Pro Tyr Ser 
    930                 935                 940                 


Thr Gln Lys Ser Ser Val Leu Pro Leu Tyr Glu Asn Thr Phe Gln Glu 
945                 950                 955                 960 


Leu Gln Val Met Arg Arg Ser Leu Asn Leu Phe Arg Thr Gln Met Met 
                965                 970                 975     


Asp Leu Glu Leu Ala Met Leu Arg Gln Gln Thr Met Val Tyr His His 
            980                 985                 990         


Met Thr Glu Glu Glu Arg Phe Glu  Val Asp Gln Leu Gln  Gly Leu Arg 
        995                 1000                 1005             


Asn Ser  Val Arg Met Glu Leu  Gln Asp Leu Glu Leu  Gln Leu Glu 
    1010                 1015                 1020             


Glu Arg  Leu Leu Gly Leu Glu  Glu Gln Leu Arg Ala  Val Arg Met 
    1025                 1030                 1035             


Pro Ser  Pro Phe Arg Ser Ser  Ala Leu Met Gly Met  Cys Gly Ser 
    1040                 1045                 1050             


Arg Ser  Ala Asp Asn Leu Ser  Cys Pro Ser Pro Leu  Asn Val Met 
    1055                 1060                 1065             


Glu Pro  Val Thr Glu Leu Met  Gln Glu Gln Ser Tyr  Leu Lys Ser 
    1070                 1075                 1080             


Glu Leu  Gly Leu Gly Leu Gly  Glu Met Gly Phe Glu  Ile Pro Pro 
    1085                 1090                 1095             


Gly Glu  Ser Ser Glu Ser Val  Phe Ser Gln Ala Thr  Ser Glu Ser 
    1100                 1105                 1110             


Ser Ser  Val Cys Ser Gly Pro  Ser His Ala Asn Arg  Arg Thr Gly 
    1115                 1120                 1125             


Val Pro  Ser Thr Ala Ser Val  Gly Lys Ser Lys Thr  Pro Leu Val 
    1130                 1135                 1140             


Ala Arg  Lys Lys Val Phe Arg  Ala Ser Val Ala Leu  Thr Pro Thr 
    1145                 1150                 1155             


Ala Pro  Ser Arg Thr Gly Ser  Val Gln Thr Pro Pro  Asp Leu Glu 
    1160                 1165                 1170             


Ser Ser  Glu Glu Val Asp Ala  Ala Glu Gly Ala Pro  Glu Val Val 
    1175                 1180                 1185             


Gly Pro  Lys Ser Glu Val Glu  Glu Gly His Gly Lys  Leu Pro Ser 
    1190                 1195                 1200             


Met Pro  Ala Ala Glu Glu Met  His Lys Asn Val Glu  Gln Asp Glu 
    1205                 1210                 1215             


Leu Gln  Gln Val Ile Arg Glu  Ile Lys Glu Ser Ile  Val Gly Glu 
    1220                 1225                 1230             


Ile Arg  Arg Glu Ile Val Ser  Gly Leu Leu Ala Ala  Val Ser Ser 
    1235                 1240                 1245             


Ser Lys  Ala Ser Asn Ser Lys  Gln Asp Tyr His 
    1250                 1255                 


<210>  3376
<211>  106
<212>  PRT
<213>  homo sapiens

<400>  3376

Met Lys Ala Lys Arg Ser His Gln Ala Ile Ile Met Ser Thr Ser Leu 
1               5                   10                  15      


Arg Val Ser Pro Ser Ile His Gly Tyr His Phe Asp Thr Ala Ser Arg 
            20                  25                  30          


Lys Lys Ala Val Gly Asn Ile Phe Glu Asn Thr Asp Gln Glu Ser Leu 
        35                  40                  45              


Glu Arg Leu Phe Arg Asn Ser Gly Asp Lys Lys Ala Glu Glu Arg Ala 
    50                  55                  60                  


Lys Ile Ile Phe Ala Ile Asp Gln Asp Val Glu Glu Lys Thr Arg Ala 
65                  70                  75                  80  


Leu Met Ala Leu Lys Lys Arg Thr Lys Asp Lys Leu Phe Gln Phe Leu 
                85                  90                  95      


Lys Leu Arg Lys Tyr Ser Ile Lys Val His 
            100                 105     


<210>  3377
<211>  436
<212>  PRT
<213>  homo sapiens

<400>  3377

Met Ala Asp Gly Gly Ser Glu Arg Ala Asp Gly Arg Ile Val Lys Met 
1               5                   10                  15      


Glu Val Asp Tyr Ser Ala Thr Val Asp Gln Arg Leu Pro Glu Cys Ala 
            20                  25                  30          


Lys Leu Ala Lys Ala Ser Asp Met Val Ser Thr Ser Arg Ile Leu Val 
        35                  40                  45              


Ala Val Val Lys Met Cys Tyr Glu Ala Lys Glu Trp Asp Leu Leu Asn 
    50                  55                  60                  


Glu Asn Ile Met Leu Leu Ser Lys Arg Arg Ser Gln Leu Lys Gln Ala 
65                  70                  75                  80  


Val Ala Lys Met Val Gln Gln Cys Cys Thr Tyr Val Glu Glu Ile Thr 
                85                  90                  95      


Asp Leu Pro Ile Lys Leu Arg Leu Ile Asp Thr Leu Arg Met Val Thr 
            100                 105                 110         


Glu Gly Lys Ile Tyr Val Glu Ile Glu Arg Ala Arg Leu Thr Lys Thr 
        115                 120                 125             


Leu Ala Thr Ile Lys Glu Gln Asn Gly Asp Val Lys Glu Ala Ala Ser 
    130                 135                 140                 


Ile Leu Gln Glu Leu Gln Val Glu Thr Tyr Gly Ser Met Glu Lys Lys 
145                 150                 155                 160 


Glu Arg Val Glu Phe Ile Leu Glu Gln Met Arg Leu Cys Leu Ala Val 
                165                 170                 175     


Lys Asp Tyr Ile Arg Thr Gln Ile Ile Ser Lys Lys Ile Asn Thr Lys 
            180                 185                 190         


Phe Phe Gln Glu Glu Asn Thr Glu Lys Leu Lys Leu Lys Tyr Tyr Asn 
        195                 200                 205             


Leu Met Ile Gln Leu Asp Gln His Glu Gly Ser Tyr Leu Ser Ile Cys 
    210                 215                 220                 


Lys His Tyr Arg Ala Ile Tyr Asp Thr Pro Cys Ile Gln Ala Glu Ser 
225                 230                 235                 240 


Glu Lys Trp Gln Gln Ala Leu Lys Ser Val Val Leu Tyr Val Ile Leu 
                245                 250                 255     


Ala Pro Phe Asp Asn Glu Gln Ser Asp Leu Val His Arg Ile Ser Gly 
            260                 265                 270         


Asp Lys Lys Leu Glu Glu Ile Pro Lys Tyr Lys Asp Leu Leu Lys Leu 
        275                 280                 285             


Phe Thr Thr Met Glu Leu Met Arg Trp Ser Thr Leu Val Glu Asp Tyr 
    290                 295                 300                 


Gly Met Glu Leu Arg Lys Gly Ser Leu Glu Ser Pro Ala Thr Asp Val 
305                 310                 315                 320 


Phe Gly Ser Thr Glu Glu Gly Glu Lys Arg Trp Lys Asp Leu Lys Asn 
                325                 330                 335     


Arg Val Val Glu His Asn Ile Arg Ile Met Ala Lys Tyr Tyr Thr Arg 
            340                 345                 350         


Ile Thr Met Lys Arg Met Ala Gln Leu Leu Asp Leu Ser Val Asp Glu 
        355                 360                 365             


Ser Glu Ala Phe Leu Ser Asn Leu Val Val Asn Lys Thr Ile Phe Ala 
    370                 375                 380                 


Lys Val Asp Arg Leu Ala Gly Ile Ile Asn Phe Gln Arg Pro Lys Asp 
385                 390                 395                 400 


Pro Asn Asn Leu Leu Asn Asp Trp Ser Gln Lys Leu Asn Ser Leu Met 
                405                 410                 415     


Ser Leu Val Asn Lys Thr Thr His Leu Ile Ala Lys Glu Glu Met Ile 
            420                 425                 430         


His Asn Leu Gln 
        435     


<210>  3378
<211>  636
<212>  PRT
<213>  homo sapiens

<400>  3378

Met Thr Thr Trp Ser Leu Arg Arg Arg Pro Ala Arg Thr Leu Gly Leu 
1               5                   10                  15      


Leu Leu Leu Val Val Leu Gly Phe Leu Val Leu Arg Arg Leu Asp Trp 
            20                  25                  30          


Ser Thr Leu Val Pro Leu Arg Leu Arg His Arg Gln Leu Gly Leu Gln 
        35                  40                  45              


Ala Lys Gly Trp Asn Phe Met Leu Glu Asp Ser Thr Phe Trp Ile Phe 
    50                  55                  60                  


Gly Gly Ser Ile His Tyr Phe Arg Val Pro Arg Glu Tyr Trp Arg Asp 
65                  70                  75                  80  


Arg Leu Leu Lys Met Lys Ala Cys Gly Leu Asn Thr Leu Thr Thr Tyr 
                85                  90                  95      


Val Pro Trp Asn Leu His Glu Pro Glu Arg Gly Lys Phe Asp Phe Ser 
            100                 105                 110         


Gly Asn Leu Asp Leu Glu Ala Phe Val Leu Met Ala Ala Glu Ile Gly 
        115                 120                 125             


Leu Trp Val Ile Leu Arg Pro Gly Pro Tyr Ile Cys Ser Glu Met Asp 
    130                 135                 140                 


Leu Gly Gly Leu Pro Ser Trp Leu Leu Gln Asp Pro Gly Met Arg Leu 
145                 150                 155                 160 


Arg Thr Thr Tyr Lys Gly Phe Thr Glu Ala Val Asp Leu Tyr Phe Asp 
                165                 170                 175     


His Leu Met Ser Arg Val Val Pro Leu Gln Tyr Lys Arg Gly Gly Pro 
            180                 185                 190         


Ile Ile Ala Val Gln Val Glu Asn Glu Tyr Gly Ser Tyr Asn Lys Asp 
        195                 200                 205             


Pro Ala Tyr Met Pro Tyr Val Lys Lys Ala Leu Glu Asp Arg Gly Ile 
    210                 215                 220                 


Val Glu Leu Leu Leu Thr Ser Asp Asn Lys Asp Gly Leu Ser Lys Gly 
225                 230                 235                 240 


Ile Val Gln Gly Val Leu Ala Thr Ile Asn Leu Gln Ser Thr His Glu 
                245                 250                 255     


Leu Gln Leu Leu Thr Thr Phe Leu Phe Asn Val Gln Gly Thr Gln Pro 
            260                 265                 270         


Lys Met Val Met Glu Tyr Trp Thr Gly Trp Phe Asp Ser Trp Gly Gly 
        275                 280                 285             


Pro His Asn Ile Leu Asp Ser Ser Glu Val Leu Lys Thr Val Ser Ala 
    290                 295                 300                 


Ile Val Asp Ala Gly Ser Ser Ile Asn Leu Tyr Met Phe His Gly Gly 
305                 310                 315                 320 


Thr Asn Phe Gly Phe Met Asn Gly Ala Met His Phe His Asp Tyr Lys 
                325                 330                 335     


Ser Asp Val Thr Ser Tyr Asp Tyr Asp Ala Val Leu Thr Glu Ala Gly 
            340                 345                 350         


Asp Tyr Thr Ala Lys Tyr Met Lys Leu Arg Asp Phe Phe Gly Ser Ile 
        355                 360                 365             


Ser Gly Ile Pro Leu Pro Pro Pro Pro Asp Leu Leu Pro Lys Met Pro 
    370                 375                 380                 


Tyr Glu Pro Leu Thr Pro Val Leu Tyr Leu Ser Leu Trp Asp Ala Leu 
385                 390                 395                 400 


Lys Tyr Leu Gly Glu Pro Ile Lys Ser Glu Lys Pro Ile Asn Met Glu 
                405                 410                 415     


Asn Leu Pro Val Asn Gly Gly Asn Gly Gln Ser Phe Gly Tyr Ile Leu 
            420                 425                 430         


Tyr Glu Thr Ser Ile Thr Ser Ser Gly Ile Leu Ser Gly His Val His 
        435                 440                 445             


Asp Arg Gly Gln Val Phe Val Asn Thr Val Ser Ile Gly Phe Leu Asp 
    450                 455                 460                 


Tyr Lys Thr Thr Lys Ile Ala Val Pro Leu Ile Gln Gly Tyr Thr Val 
465                 470                 475                 480 


Leu Arg Ile Leu Val Glu Asn Arg Gly Arg Val Asn Tyr Gly Glu Asn 
                485                 490                 495     


Ile Asp Asp Gln Arg Lys Gly Leu Ile Gly Asn Leu Tyr Leu Asn Asp 
            500                 505                 510         


Ser Pro Leu Lys Asn Phe Arg Ile Tyr Ser Leu Asp Met Lys Lys Ser 
        515                 520                 525             


Phe Phe Gln Arg Phe Gly Leu Asp Lys Trp Ser Ser Leu Pro Glu Thr 
    530                 535                 540                 


Pro Thr Leu Pro Ala Phe Phe Leu Gly Ser Leu Ser Ile Ser Ser Thr 
545                 550                 555                 560 


Pro Cys Asp Thr Phe Leu Lys Leu Glu Gly Trp Glu Lys Gly Val Val 
                565                 570                 575     


Phe Ile Asn Gly Gln Asn Leu Gly Arg Tyr Trp Asn Ile Gly Pro Gln 
            580                 585                 590         


Lys Thr Leu Tyr Leu Pro Gly Pro Trp Leu Ser Ser Gly Ile Asn Gln 
        595                 600                 605             


Val Ile Val Phe Glu Glu Thr Met Ala Gly Pro Ala Leu Gln Phe Thr 
    610                 615                 620                 


Glu Thr Pro His Leu Gly Arg Asn Gln Tyr Ile Lys 
625                 630                 635     


<210>  3379
<211>  501
<212>  PRT
<213>  homo sapiens

<400>  3379

Met Asp Glu Phe His Pro Phe Ile Glu Ala Leu Leu Pro His Val Arg 
1               5                   10                  15      


Ala Phe Ala Tyr Thr Trp Phe Asn Leu Gln Ala Arg Lys Arg Lys Tyr 
            20                  25                  30          


Phe Lys Lys His Glu Lys Arg Met Ser Lys Glu Glu Glu Arg Ala Val 
        35                  40                  45              


Lys Asp Glu Leu Leu Ser Glu Lys Pro Glu Val Lys Gln Lys Trp Ala 
    50                  55                  60                  


Ser Arg Leu Leu Ala Lys Leu Arg Lys Asp Ile Arg Pro Glu Tyr Arg 
65                  70                  75                  80  


Glu Asp Phe Val Leu Thr Val Thr Gly Lys Lys Pro Pro Cys Cys Val 
                85                  90                  95      


Leu Ser Asn Pro Asp Gln Lys Gly Lys Met Arg Arg Ile Asp Cys Leu 
            100                 105                 110         


Arg Gln Ala Asp Lys Val Trp Arg Leu Asp Leu Val Met Val Ile Leu 
        115                 120                 125             


Phe Lys Gly Ile Pro Leu Glu Ser Thr Asp Gly Glu Arg Leu Val Lys 
    130                 135                 140                 


Ser Pro Gln Cys Ser Asn Pro Gly Leu Cys Val Gln Pro His His Ile 
145                 150                 155                 160 


Gly Val Ser Val Lys Glu Leu Asp Leu Tyr Leu Ala Tyr Phe Val His 
                165                 170                 175     


Ala Ala Asp Ser Ser Gln Ser Glu Ser Pro Ser Gln Pro Ser Asp Ala 
            180                 185                 190         


Asp Ile Lys Asp Gln Pro Glu Asn Gly His Leu Gly Phe Gln Asp Ser 
        195                 200                 205             


Phe Val Thr Ser Gly Val Phe Ser Val Thr Glu Leu Val Arg Val Ser 
    210                 215                 220                 


Gln Thr Pro Ile Ala Ala Gly Thr Gly Pro Asn Phe Ser Leu Ser Asp 
225                 230                 235                 240 


Leu Glu Ser Ser Ser Tyr Tyr Ser Met Ser Pro Gly Ala Met Arg Arg 
                245                 250                 255     


Ser Leu Pro Ser Thr Ser Ser Thr Ser Ser Thr Lys Arg Leu Lys Ser 
            260                 265                 270         


Val Glu Asp Glu Met Asp Ser Pro Gly Glu Glu Pro Phe Tyr Thr Gly 
        275                 280                 285             


Gln Gly Arg Ser Pro Gly Ser Gly Ser Gln Ser Ser Gly Trp His Glu 
    290                 295                 300                 


Val Glu Pro Gly Met Pro Ser Pro Thr Thr Leu Lys Lys Ser Glu Lys 
305                 310                 315                 320 


Ser Gly Phe Ser Ser Pro Ser Pro Ser Gln Thr Ser Ser Leu Gly Thr 
                325                 330                 335     


Ala Phe Thr Gln His His Arg Pro Val Ile Thr Gly Pro Arg Ala Ser 
            340                 345                 350         


Pro His Ala Thr Pro Ser Thr Leu His Phe Pro Thr Ser Pro Ile Ile 
        355                 360                 365             


Gln Gln Pro Gly Pro Tyr Phe Ser His Pro Ala Ile Arg Tyr His Pro 
    370                 375                 380                 


Gln Glu Thr Leu Lys Glu Phe Val Gln Leu Val Cys Pro Asp Ala Gly 
385                 390                 395                 400 


Gln Gln Ala Gly Gln Val Gly Phe Leu Asn Pro Asn Gly Ser Ser Gln 
                405                 410                 415     


Gly Lys Val His Asn Pro Phe Leu Pro Thr Pro Met Leu Pro Pro Pro 
            420                 425                 430         


Pro Pro Pro Pro Met Ala Arg Pro Val Pro Leu Pro Val Pro Asp Thr 
        435                 440                 445             


Lys Pro Pro Thr Thr Ser Thr Glu Gly Gly Ala Ala Ser Pro Thr Ser 
    450                 455                 460                 


Pro Thr Tyr Ser Thr Pro Ser Thr Ser Pro Ala Asn Arg Phe Val Ser 
465                 470                 475                 480 


Val Gly Pro Arg Asp Pro Ser Phe Val Asn Ile Pro Gln Gln Thr Gln 
                485                 490                 495     


Ser Trp Tyr Leu Gly 
            500     


<210>  3380
<211>  532
<212>  PRT
<213>  homo sapiens

<400>  3380

Met Pro Gln Leu Tyr Ile Tyr Ile Arg Leu Leu Gly Ala Tyr Leu Phe 
1               5                   10                  15      


Ile Ile Ser Arg Val Gln Gly Gln Asn Leu Asp Ser Met Leu His Gly 
            20                  25                  30          


Thr Gly Met Lys Ser Asp Ser Asp Gln Lys Lys Ser Glu Asn Gly Val 
        35                  40                  45              


Thr Leu Ala Pro Glu Asp Thr Leu Pro Phe Leu Lys Cys Tyr Cys Ser 
    50                  55                  60                  


Gly His Cys Pro Asp Asp Ala Ile Asn Asn Thr Cys Ile Thr Asn Gly 
65                  70                  75                  80  


His Cys Phe Ala Ile Ile Glu Glu Asp Asp Gln Gly Glu Thr Thr Leu 
                85                  90                  95      


Ala Ser Gly Cys Met Lys Tyr Glu Gly Ser Asp Phe Gln Cys Lys Asp 
            100                 105                 110         


Ser Pro Lys Ala Gln Leu Arg Arg Thr Ile Glu Cys Cys Arg Thr Asn 
        115                 120                 125             


Leu Cys Asn Gln Tyr Leu Gln Pro Thr Leu Pro Pro Val Val Ile Gly 
    130                 135                 140                 


Pro Phe Phe Asp Gly Ser Ile Arg Trp Leu Val Leu Leu Ile Ser Met 
145                 150                 155                 160 


Ala Val Cys Ile Ile Ala Met Ile Ile Phe Ser Ser Cys Phe Cys Tyr 
                165                 170                 175     


Lys His Tyr Cys Lys Ser Ile Ser Ser Arg Arg Arg Tyr Asn Arg Asp 
            180                 185                 190         


Leu Glu Gln Asp Glu Ala Phe Ile Pro Val Gly Glu Ser Leu Lys Asp 
        195                 200                 205             


Leu Ile Asp Gln Ser Gln Ser Ser Gly Ser Gly Ser Gly Leu Pro Leu 
    210                 215                 220                 


Leu Val Gln Arg Thr Ile Ala Lys Gln Ile Gln Met Val Arg Gln Val 
225                 230                 235                 240 


Gly Lys Gly Arg Tyr Gly Glu Val Trp Met Gly Lys Trp Arg Gly Glu 
                245                 250                 255     


Lys Val Ala Val Lys Val Phe Phe Thr Thr Glu Glu Ala Ser Trp Phe 
            260                 265                 270         


Arg Glu Thr Glu Ile Tyr Gln Thr Val Leu Met Arg His Glu Asn Ile 
        275                 280                 285             


Leu Gly Phe Ile Ala Ala Asp Ile Lys Gly Thr Gly Ser Trp Thr Gln 
    290                 295                 300                 


Leu Tyr Leu Ile Thr Asp Tyr His Glu Asn Gly Ser Leu Tyr Asp Phe 
305                 310                 315                 320 


Leu Lys Cys Ala Thr Leu Asp Thr Arg Ala Leu Leu Lys Leu Ala Tyr 
                325                 330                 335     


Ser Ala Ala Cys Gly Leu Cys His Leu His Thr Glu Ile Tyr Gly Thr 
            340                 345                 350         


Gln Gly Lys Pro Ala Ile Ala His Arg Asp Leu Lys Ser Lys Asn Ile 
        355                 360                 365             


Leu Ile Lys Lys Asn Gly Ser Cys Cys Ile Ala Asp Leu Gly Leu Ala 
    370                 375                 380                 


Val Lys Phe Asn Ser Asp Thr Asn Glu Val Asp Val Pro Leu Asn Thr 
385                 390                 395                 400 


Arg Val Gly Thr Lys Arg Tyr Met Ala Pro Glu Val Leu Asp Glu Ser 
                405                 410                 415     


Leu Asn Lys Asn His Phe Gln Pro Tyr Ile Met Ala Asp Ile Tyr Ser 
            420                 425                 430         


Phe Gly Leu Ile Ile Trp Glu Met Ala Arg Arg Cys Ile Thr Gly Gly 
        435                 440                 445             


Ile Val Glu Glu Tyr Gln Leu Pro Tyr Tyr Asn Met Val Pro Ser Asp 
    450                 455                 460                 


Pro Ser Tyr Glu Asp Met Arg Glu Val Val Cys Val Lys Arg Leu Arg 
465                 470                 475                 480 


Pro Ile Val Ser Asn Arg Trp Asn Ser Asp Glu Cys Leu Arg Ala Val 
                485                 490                 495     


Leu Lys Leu Met Ser Glu Cys Trp Ala His Asn Pro Ala Ser Arg Leu 
            500                 505                 510         


Thr Ala Leu Arg Ile Lys Lys Thr Leu Ala Lys Met Val Glu Ser Gln 
        515                 520                 525             


Asp Val Lys Ile 
    530         


<210>  3381
<211>  883
<212>  PRT
<213>  homo sapiens

<400>  3381

Met Gln Lys Ile Met His Ile Ser Val Leu Leu Ser Pro Val Leu Trp 
1               5                   10                  15      


Gly Leu Ile Phe Gly Val Ser Ser Asn Ser Ile Gln Ile Gly Gly Leu 
            20                  25                  30          


Phe Pro Arg Gly Ala Asp Gln Glu Tyr Ser Ala Phe Arg Val Gly Met 
        35                  40                  45              


Val Gln Phe Ser Thr Ser Glu Phe Arg Leu Thr Pro His Ile Asp Asn 
    50                  55                  60                  


Leu Glu Val Ala Asn Ser Phe Ala Val Thr Asn Ala Phe Cys Ser Gln 
65                  70                  75                  80  


Phe Ser Arg Gly Val Tyr Ala Ile Phe Gly Phe Tyr Asp Lys Lys Ser 
                85                  90                  95      


Val Asn Thr Ile Thr Ser Phe Cys Gly Thr Leu His Val Ser Phe Ile 
            100                 105                 110         


Thr Pro Ser Phe Pro Thr Asp Gly Thr His Pro Phe Val Ile Gln Met 
        115                 120                 125             


Arg Pro Asp Leu Lys Gly Ala Leu Leu Ser Leu Ile Glu Tyr Tyr Gln 
    130                 135                 140                 


Trp Asp Lys Phe Ala Tyr Leu Tyr Asp Ser Asp Arg Gly Leu Ser Thr 
145                 150                 155                 160 


Leu Gln Ala Val Leu Asp Ser Ala Ala Glu Lys Lys Trp Gln Val Thr 
                165                 170                 175     


Ala Ile Asn Val Gly Asn Ile Asn Asn Asp Lys Lys Asp Glu Met Tyr 
            180                 185                 190         


Arg Ser Leu Phe Gln Asp Leu Glu Leu Lys Lys Glu Arg Arg Val Ile 
        195                 200                 205             


Leu Asp Cys Glu Arg Asp Lys Val Asn Asp Ile Val Asp Gln Val Ile 
    210                 215                 220                 


Thr Ile Gly Lys His Val Lys Gly Tyr His Tyr Ile Ile Ala Asn Leu 
225                 230                 235                 240 


Gly Phe Thr Asp Gly Asp Leu Leu Lys Ile Gln Phe Gly Gly Ala Asn 
                245                 250                 255     


Val Ser Gly Phe Gln Ile Val Asp Tyr Asp Asp Ser Leu Val Ser Lys 
            260                 265                 270         


Phe Ile Glu Arg Trp Ser Thr Leu Glu Glu Lys Glu Tyr Pro Gly Ala 
        275                 280                 285             


His Thr Thr Thr Ile Lys Tyr Thr Ser Ala Leu Thr Tyr Asp Ala Val 
    290                 295                 300                 


Gln Val Met Thr Glu Ala Phe Arg Asn Leu Arg Lys Gln Arg Ile Glu 
305                 310                 315                 320 


Ile Ser Arg Arg Gly Asn Ala Gly Asp Cys Leu Ala Asn Pro Ala Val 
                325                 330                 335     


Pro Trp Gly Gln Gly Val Glu Ile Glu Arg Ala Leu Lys Gln Val Gln 
            340                 345                 350         


Val Glu Gly Leu Ser Gly Asn Ile Lys Phe Asp Gln Asn Gly Lys Arg 
        355                 360                 365             


Ile Asn Tyr Thr Ile Asn Ile Met Glu Leu Lys Thr Asn Gly Pro Arg 
    370                 375                 380                 


Lys Ile Gly Tyr Trp Ser Glu Val Asp Lys Met Val Val Thr Leu Thr 
385                 390                 395                 400 


Glu Leu Pro Ser Gly Asn Asp Thr Ser Gly Leu Glu Asn Lys Thr Val 
                405                 410                 415     


Val Val Thr Thr Ile Leu Glu Ser Pro Tyr Val Met Met Lys Lys Asn 
            420                 425                 430         


His Glu Met Leu Glu Gly Asn Glu Arg Tyr Glu Gly Tyr Cys Val Asp 
        435                 440                 445             


Leu Ala Ala Glu Ile Ala Lys His Cys Gly Phe Lys Tyr Lys Leu Thr 
    450                 455                 460                 


Ile Val Gly Asp Gly Lys Tyr Gly Ala Arg Asp Ala Asp Thr Lys Ile 
465                 470                 475                 480 


Trp Asn Gly Met Val Gly Glu Leu Val Tyr Gly Lys Ala Asp Ile Ala 
                485                 490                 495     


Ile Ala Pro Leu Thr Ile Thr Leu Val Arg Glu Glu Val Ile Asp Phe 
            500                 505                 510         


Ser Lys Pro Phe Met Ser Leu Gly Ile Ser Ile Met Ile Lys Lys Pro 
        515                 520                 525             


Gln Lys Ser Lys Pro Gly Val Phe Ser Phe Leu Asp Pro Leu Ala Tyr 
    530                 535                 540                 


Glu Ile Trp Met Cys Ile Val Phe Ala Tyr Ile Gly Val Ser Val Val 
545                 550                 555                 560 


Leu Phe Leu Val Ser Arg Phe Ser Pro Tyr Glu Trp His Thr Glu Glu 
                565                 570                 575     


Phe Glu Asp Gly Arg Glu Thr Gln Ser Ser Glu Ser Thr Asn Glu Phe 
            580                 585                 590         


Gly Ile Phe Asn Ser Leu Trp Phe Ser Leu Gly Ala Phe Met Arg Gln 
        595                 600                 605             


Gly Cys Asp Ile Ser Pro Arg Ser Leu Ser Gly Arg Ile Val Gly Gly 
    610                 615                 620                 


Val Trp Trp Phe Phe Thr Leu Ile Ile Ile Ser Ser Tyr Thr Ala Asn 
625                 630                 635                 640 


Leu Ala Ala Phe Leu Thr Val Glu Arg Met Val Ser Pro Ile Glu Ser 
                645                 650                 655     


Ala Glu Asp Leu Ser Lys Gln Thr Glu Ile Ala Tyr Gly Thr Leu Asp 
            660                 665                 670         


Ser Gly Ser Thr Lys Glu Phe Phe Arg Arg Ser Lys Ile Ala Val Phe 
        675                 680                 685             


Asp Lys Met Trp Thr Tyr Met Arg Ser Ala Glu Pro Ser Val Phe Val 
    690                 695                 700                 


Arg Thr Thr Ala Glu Gly Val Ala Arg Val Arg Lys Ser Lys Gly Lys 
705                 710                 715                 720 


Tyr Ala Tyr Leu Leu Glu Ser Thr Met Asn Glu Tyr Ile Glu Gln Arg 
                725                 730                 735     


Lys Pro Cys Asp Thr Met Lys Val Gly Gly Asn Leu Asp Ser Lys Gly 
            740                 745                 750         


Tyr Gly Ile Ala Thr Pro Lys Gly Ser Ser Leu Arg Asn Ala Val Asn 
        755                 760                 765             


Leu Ala Val Leu Lys Leu Asn Glu Gln Gly Leu Leu Asp Lys Leu Lys 
    770                 775                 780                 


Asn Lys Trp Trp Tyr Asp Lys Gly Glu Cys Gly Ser Gly Gly Gly Asp 
785                 790                 795                 800 


Ser Lys Glu Lys Thr Ser Ala Leu Ser Leu Ser Asn Val Ala Gly Val 
                805                 810                 815     


Phe Tyr Ile Leu Val Gly Gly Leu Gly Leu Ala Met Leu Val Ala Leu 
            820                 825                 830         


Ile Glu Phe Cys Tyr Lys Ser Arg Ala Glu Ala Lys Arg Met Lys Val 
        835                 840                 845             


Ala Lys Asn Ala Gln Asn Ile Asn Pro Ser Ser Ser Gln Asn Ser Gln 
    850                 855                 860                 


Asn Phe Ala Thr Tyr Lys Glu Gly Tyr Asn Val Tyr Gly Ile Glu Ser 
865                 870                 875                 880 


Val Lys Ile 
            


<210>  3382
<211>  836
<212>  PRT
<213>  homo sapiens

<400>  3382

Met Val Gln Phe Ser Thr Ser Glu Phe Arg Leu Thr Pro His Ile Asp 
1               5                   10                  15      


Asn Leu Glu Val Ala Asn Ser Phe Ala Val Thr Asn Ala Phe Cys Ser 
            20                  25                  30          


Gln Phe Ser Arg Gly Val Tyr Ala Ile Phe Gly Phe Tyr Asp Lys Lys 
        35                  40                  45              


Ser Val Asn Thr Ile Thr Ser Phe Cys Gly Thr Leu His Val Ser Phe 
    50                  55                  60                  


Ile Thr Pro Ser Phe Pro Thr Asp Gly Thr His Pro Phe Val Ile Gln 
65                  70                  75                  80  


Met Arg Pro Asp Leu Lys Gly Ala Leu Leu Ser Leu Ile Glu Tyr Tyr 
                85                  90                  95      


Gln Trp Asp Lys Phe Ala Tyr Leu Tyr Asp Ser Asp Arg Gly Leu Ser 
            100                 105                 110         


Thr Leu Gln Ala Val Leu Asp Ser Ala Ala Glu Lys Lys Trp Gln Val 
        115                 120                 125             


Thr Ala Ile Asn Val Gly Asn Ile Asn Asn Asp Lys Lys Asp Glu Met 
    130                 135                 140                 


Tyr Arg Ser Leu Phe Gln Asp Leu Glu Leu Lys Lys Glu Arg Arg Val 
145                 150                 155                 160 


Ile Leu Asp Cys Glu Arg Asp Lys Val Asn Asp Ile Val Asp Gln Val 
                165                 170                 175     


Ile Thr Ile Gly Lys His Val Lys Gly Tyr His Tyr Ile Ile Ala Asn 
            180                 185                 190         


Leu Gly Phe Thr Asp Gly Asp Leu Leu Lys Ile Gln Phe Gly Gly Ala 
        195                 200                 205             


Asn Val Ser Gly Phe Gln Ile Val Asp Tyr Asp Asp Ser Leu Val Ser 
    210                 215                 220                 


Lys Phe Ile Glu Arg Trp Ser Thr Leu Glu Glu Lys Glu Tyr Pro Gly 
225                 230                 235                 240 


Ala His Thr Thr Thr Ile Lys Tyr Thr Ser Ala Leu Thr Tyr Asp Ala 
                245                 250                 255     


Val Gln Val Met Thr Glu Ala Phe Arg Asn Leu Arg Lys Gln Arg Ile 
            260                 265                 270         


Glu Ile Ser Arg Arg Gly Asn Ala Gly Asp Cys Leu Ala Asn Pro Ala 
        275                 280                 285             


Val Pro Trp Gly Gln Gly Val Glu Ile Glu Arg Ala Leu Lys Gln Val 
    290                 295                 300                 


Gln Val Glu Gly Leu Ser Gly Asn Ile Lys Phe Asp Gln Asn Gly Lys 
305                 310                 315                 320 


Arg Ile Asn Tyr Thr Ile Asn Ile Met Glu Leu Lys Thr Asn Gly Pro 
                325                 330                 335     


Arg Lys Ile Gly Tyr Trp Ser Glu Val Asp Lys Met Val Val Thr Leu 
            340                 345                 350         


Thr Glu Leu Pro Ser Gly Asn Asp Thr Ser Gly Leu Glu Asn Lys Thr 
        355                 360                 365             


Val Val Val Thr Thr Ile Leu Glu Ser Pro Tyr Val Met Met Lys Lys 
    370                 375                 380                 


Asn His Glu Met Leu Glu Gly Asn Glu Arg Tyr Glu Gly Tyr Cys Val 
385                 390                 395                 400 


Asp Leu Ala Ala Glu Ile Ala Lys His Cys Gly Phe Lys Tyr Lys Leu 
                405                 410                 415     


Thr Ile Val Gly Asp Gly Lys Tyr Gly Ala Arg Asp Ala Asp Thr Lys 
            420                 425                 430         


Ile Trp Asn Gly Met Val Gly Glu Leu Val Tyr Gly Lys Ala Asp Ile 
        435                 440                 445             


Ala Ile Ala Pro Leu Thr Ile Thr Leu Val Arg Glu Glu Val Ile Asp 
    450                 455                 460                 


Phe Ser Lys Pro Phe Met Ser Leu Gly Ile Ser Ile Met Ile Lys Lys 
465                 470                 475                 480 


Pro Gln Lys Ser Lys Pro Gly Val Phe Ser Phe Leu Asp Pro Leu Ala 
                485                 490                 495     


Tyr Glu Ile Trp Met Cys Ile Val Phe Ala Tyr Ile Gly Val Ser Val 
            500                 505                 510         


Val Leu Phe Leu Val Ser Arg Phe Ser Pro Tyr Glu Trp His Thr Glu 
        515                 520                 525             


Glu Phe Glu Asp Gly Arg Glu Thr Gln Ser Ser Glu Ser Thr Asn Glu 
    530                 535                 540                 


Phe Gly Ile Phe Asn Ser Leu Trp Phe Ser Leu Gly Ala Phe Met Arg 
545                 550                 555                 560 


Gln Gly Cys Asp Ile Ser Pro Arg Ser Leu Ser Gly Arg Ile Val Gly 
                565                 570                 575     


Gly Val Trp Trp Phe Phe Thr Leu Ile Ile Ile Ser Ser Tyr Thr Ala 
            580                 585                 590         


Asn Leu Ala Ala Phe Leu Thr Val Glu Arg Met Val Ser Pro Ile Glu 
        595                 600                 605             


Ser Ala Glu Asp Leu Ser Lys Gln Thr Glu Ile Ala Tyr Gly Thr Leu 
    610                 615                 620                 


Asp Ser Gly Ser Thr Lys Glu Phe Phe Arg Arg Ser Lys Ile Ala Val 
625                 630                 635                 640 


Phe Asp Lys Met Trp Thr Tyr Met Arg Ser Ala Glu Pro Ser Val Phe 
                645                 650                 655     


Val Arg Thr Thr Ala Glu Gly Val Ala Arg Val Arg Lys Ser Lys Gly 
            660                 665                 670         


Lys Tyr Ala Tyr Leu Leu Glu Ser Thr Met Asn Glu Tyr Ile Glu Gln 
        675                 680                 685             


Arg Lys Pro Cys Asp Thr Met Lys Val Gly Gly Asn Leu Asp Ser Lys 
    690                 695                 700                 


Gly Tyr Gly Ile Ala Thr Pro Lys Gly Ser Ser Leu Arg Thr Pro Val 
705                 710                 715                 720 


Asn Leu Ala Val Leu Lys Leu Ser Glu Gln Gly Val Leu Asp Lys Leu 
                725                 730                 735     


Lys Asn Lys Trp Trp Tyr Asp Lys Gly Glu Cys Gly Ala Lys Asp Ser 
            740                 745                 750         


Gly Ser Lys Glu Lys Thr Ser Ala Leu Ser Leu Ser Asn Val Ala Gly 
        755                 760                 765             


Val Phe Tyr Ile Leu Val Gly Gly Leu Gly Leu Ala Met Leu Val Ala 
    770                 775                 780                 


Leu Ile Glu Phe Cys Tyr Lys Ser Arg Ala Glu Ala Lys Arg Met Lys 
785                 790                 795                 800 


Val Ala Lys Asn Ala Gln Asn Ile Asn Pro Ser Ser Ser Gln Asn Ser 
                805                 810                 815     


Gln Asn Phe Ala Thr Tyr Lys Glu Gly Tyr Asn Val Tyr Gly Ile Glu 
            820                 825                 830         


Ser Val Lys Ile 
        835     


<210>  3383
<211>  258
<212>  PRT
<213>  homo sapiens

<400>  3383

Met Ile Ala Ile Ser Ala Val Ser Ser Ala Leu Leu Phe Ser Leu Leu 
1               5                   10                  15      


Cys Glu Ala Ser Thr Val Val Leu Leu Asn Ser Thr Asp Ser Ser Pro 
            20                  25                  30          


Pro Thr Asn Asn Phe Thr Asp Ile Glu Ala Ala Leu Lys Ala Gln Leu 
        35                  40                  45              


Asp Ser Ala Asp Ile Pro Lys Ala Arg Arg Lys Arg Tyr Ile Ser Gln 
    50                  55                  60                  


Asn Asp Met Ile Ala Ile Leu Asp Tyr His Asn Gln Val Arg Gly Lys 
65                  70                  75                  80  


Val Phe Pro Pro Ala Ala Asn Met Glu Tyr Met Val Trp Asp Glu Asn 
                85                  90                  95      


Leu Ala Lys Ser Ala Glu Ala Trp Ala Ala Thr Cys Ile Trp Asp His 
            100                 105                 110         


Gly Pro Ser Tyr Leu Leu Arg Phe Leu Gly Gln Asn Leu Ser Val Arg 
        115                 120                 125             


Thr Gly Arg Tyr Arg Ser Ile Leu Gln Leu Val Lys Pro Trp Tyr Asp 
    130                 135                 140                 


Glu Val Lys Asp Tyr Ala Phe Pro Tyr Pro Gln Asp Cys Asn Pro Arg 
145                 150                 155                 160 


Cys Pro Met Arg Cys Phe Gly Pro Met Cys Thr His Tyr Thr Gln Met 
                165                 170                 175     


Val Trp Ala Thr Ser Asn Arg Ile Gly Cys Ala Ile His Thr Cys Gln 
            180                 185                 190         


Asn Met Asn Val Trp Gly Ser Val Trp Arg Arg Ala Val Tyr Leu Val 
        195                 200                 205             


Cys Asn Tyr Ala Pro Lys Gly Asn Trp Ile Gly Glu Ala Pro Tyr Lys 
    210                 215                 220                 


Val Gly Val Pro Cys Ser Ser Cys Pro Pro Ser Tyr Gly Gly Ser Cys 
225                 230                 235                 240 


Thr Asp Asn Leu Cys Phe Pro Gly Val Thr Ser Asn Tyr Leu Tyr Trp 
                245                 250                 255     


Phe Lys 
        


<210>  3384
<211>  1751
<212>  PRT
<213>  homo sapiens

<400>  3384

Met Ala Pro Tyr Pro Cys Gly Cys His Ile Leu Leu Leu Leu Phe Cys 
1               5                   10                  15      


Cys Leu Ala Ala Ala Arg Ala Asn Leu Leu Asn Leu Asn Trp Leu Trp 
            20                  25                  30          


Phe Asn Asn Glu Asp Thr Ser His Ala Ala Thr Thr Ile Pro Glu Pro 
        35                  40                  45              


Gln Gly Pro Leu Pro Val Gln Pro Thr Ala Asp Thr Thr Thr His Val 
    50                  55                  60                  


Thr Pro Arg Asn Gly Ser Thr Glu Pro Ala Thr Ala Pro Gly Ser Pro 
65                  70                  75                  80  


Glu Pro Pro Ser Glu Leu Leu Glu Asp Gly Gln Asp Thr Pro Thr Ser 
                85                  90                  95      


Ala Glu Ser Pro Asp Ala Pro Glu Glu Asn Ile Ala Gly Val Gly Ala 
            100                 105                 110         


Glu Ile Leu Asn Val Ala Lys Gly Ile Arg Ser Phe Val Gln Leu Trp 
        115                 120                 125             


Asn Asp Thr Val Pro Thr Glu Ser Leu Ala Arg Ala Glu Thr Leu Val 
    130                 135                 140                 


Leu Glu Thr Pro Val Gly Pro Leu Ala Leu Ala Gly Pro Ser Ser Thr 
145                 150                 155                 160 


Pro Gln Glu Asn Gly Thr Thr Leu Trp Pro Ser Arg Gly Ile Pro Ser 
                165                 170                 175     


Ser Pro Gly Ala His Thr Thr Glu Ala Gly Thr Leu Pro Ala Pro Thr 
            180                 185                 190         


Pro Ser Pro Pro Ser Leu Gly Arg Pro Trp Ala Pro Leu Thr Gly Pro 
        195                 200                 205             


Ser Val Pro Pro Pro Ser Ser Gly Arg Ala Ser Leu Ser Ser Leu Leu 
    210                 215                 220                 


Gly Gly Ala Pro Pro Trp Gly Ser Leu Gln Asp Pro Asp Ser Gln Gly 
225                 230                 235                 240 


Leu Ser Pro Ala Ala Ala Ala Pro Ser Gln Gln Leu Gln Arg Pro Asp 
                245                 250                 255     


Val Arg Leu Arg Thr Pro Leu Leu His Pro Leu Val Met Gly Ser Leu 
            260                 265                 270         


Gly Lys His Ala Ala Pro Ser Ala Phe Ser Ser Gly Leu Pro Gly Ala 
        275                 280                 285             


Leu Ser Gln Val Ala Val Thr Thr Leu Thr Arg Asp Ser Gly Ala Trp 
    290                 295                 300                 


Val Ser His Val Ala Asn Ser Val Gly Pro Gly Leu Ala Asn Asn Ser 
305                 310                 315                 320 


Ala Leu Leu Gly Ala Asp Pro Glu Ala Pro Ala Gly Arg Cys Leu Pro 
                325                 330                 335     


Leu Pro Pro Ser Leu Pro Val Cys Gly His Leu Gly Ile Ser Arg Phe 
            340                 345                 350         


Trp Leu Pro Asn His Leu His His Glu Ser Gly Glu Gln Val Arg Ala 
        355                 360                 365             


Gly Ala Arg Ala Trp Gly Gly Leu Leu Gln Thr His Cys His Pro Phe 
    370                 375                 380                 


Leu Ala Trp Phe Phe Cys Leu Leu Leu Val Pro Pro Cys Gly Ser Val 
385                 390                 395                 400 


Pro Pro Pro Ala Pro Pro Pro Cys Cys Gln Phe Cys Glu Ala Leu Gln 
                405                 410                 415     


Asp Ala Cys Trp Ser Arg Leu Gly Gly Gly Arg Leu Pro Val Ala Cys 
            420                 425                 430         


Ala Ser Leu Pro Thr Gln Glu Asp Gly Tyr Cys Val Leu Ile Gly Pro 
        435                 440                 445             


Ala Ala Glu Arg Ile Ser Glu Glu Val Gly Leu Leu Gln Leu Leu Gly 
    450                 455                 460                 


Asp Pro Pro Pro Gln Gln Val Thr Gln Thr Asp Asp Pro Asp Val Gly 
465                 470                 475                 480 


Leu Ala Tyr Val Phe Gly Pro Asp Ala Asn Ser Gly Gln Val Ala Arg 
                485                 490                 495     


Tyr His Phe Pro Ser Leu Phe Phe Arg Asp Phe Ser Leu Leu Phe His 
            500                 505                 510         


Ile Arg Pro Ala Thr Glu Gly Pro Gly Val Leu Phe Ala Ile Thr Asp 
        515                 520                 525             


Ser Ala Gln Ala Met Val Leu Leu Gly Val Lys Leu Ser Gly Val Gln 
    530                 535                 540                 


Asp Gly His Gln Asp Ile Ser Leu Leu Tyr Thr Glu Pro Gly Ala Gly 
545                 550                 555                 560 


Gln Thr His Thr Ala Ala Ser Phe Arg Leu Pro Ala Phe Val Gly Gln 
                565                 570                 575     


Trp Thr His Leu Ala Leu Ser Val Ala Gly Gly Phe Val Ala Leu Tyr 
            580                 585                 590         


Val Asp Cys Glu Glu Phe Gln Arg Met Pro Leu Ala Arg Ser Ser Arg 
        595                 600                 605             


Gly Leu Glu Leu Glu Pro Gly Ala Gly Leu Phe Val Ala Gln Ala Gly 
    610                 615                 620                 


Gly Ala Asp Pro Asp Lys Phe Gln Gly Val Ile Ala Glu Leu Lys Val 
625                 630                 635                 640 


Arg Arg Asp Pro Gln Val Ser Pro Met His Cys Leu Asp Glu Glu Gly 
                645                 650                 655     


Asp Asp Ser Asp Gly Ala Ser Gly Asp Ser Gly Ser Gly Leu Gly Asp 
            660                 665                 670         


Ala Arg Glu Leu Leu Arg Glu Glu Thr Gly Ala Ala Leu Lys Pro Arg 
        675                 680                 685             


Leu Pro Ala Pro Pro Pro Val Thr Thr Pro Pro Leu Ala Gly Gly Ser 
    690                 695                 700                 


Ser Thr Glu Asp Ser Arg Ser Glu Glu Val Glu Glu Gln Thr Thr Val 
705                 710                 715                 720 


Ala Ser Leu Gly Ala Gln Thr Leu Pro Gly Ser Asp Ser Val Ser Thr 
                725                 730                 735     


Trp Asp Gly Ser Val Arg Thr Pro Gly Gly Arg Val Lys Glu Gly Gly 
            740                 745                 750         


Leu Lys Gly Gln Lys Gly Glu Pro Gly Val Pro Gly Pro Pro Gly Arg 
        755                 760                 765             


Ala Gly Pro Pro Gly Ser Pro Cys Leu Pro Gly Pro Pro Gly Leu Pro 
    770                 775                 780                 


Cys Pro Val Ser Pro Leu Gly Pro Ala Gly Pro Ala Leu Gln Thr Val 
785                 790                 795                 800 


Pro Gly Pro Gln Gly Pro Pro Gly Pro Pro Gly Arg Asp Gly Thr Pro 
                805                 810                 815     


Gly Arg Asp Gly Glu Pro Gly Asp Pro Gly Glu Asp Gly Lys Pro Gly 
            820                 825                 830         


Asp Thr Gly Pro Gln Gly Phe Pro Gly Thr Pro Gly Asp Val Gly Pro 
        835                 840                 845             


Lys Gly Asp Lys Gly Asp Pro Gly Val Gly Glu Arg Gly Pro Pro Gly 
    850                 855                 860                 


Pro Gln Gly Pro Pro Gly Pro Pro Gly Pro Ser Phe Arg His Asp Lys 
865                 870                 875                 880 


Leu Thr Phe Ile Asp Met Glu Gly Ser Gly Phe Gly Gly Asp Leu Glu 
                885                 890                 895     


Ala Leu Arg Gly Pro Arg Gly Phe Pro Gly Pro Pro Gly Pro Pro Gly 
            900                 905                 910         


Val Pro Gly Leu Pro Gly Glu Pro Gly Arg Phe Gly Val Asn Ser Ser 
        915                 920                 925             


Asp Val Pro Gly Pro Ala Gly Leu Pro Gly Val Pro Gly Arg Glu Gly 
    930                 935                 940                 


Pro Pro Gly Phe Pro Gly Leu Pro Gly Pro Pro Gly Pro Pro Gly Arg 
945                 950                 955                 960 


Glu Gly Pro Pro Gly Arg Thr Gly Gln Lys Gly Ser Leu Gly Glu Ala 
                965                 970                 975     


Gly Ala Pro Gly His Lys Gly Ser Lys Gly Ala Pro Gly Pro Ala Gly 
            980                 985                 990         


Ala Arg Gly Glu Ser Gly Leu Ala  Gly Ala Pro Gly Pro  Ala Gly Pro 
        995                 1000                 1005             


Pro Gly  Pro Pro Gly Pro Pro  Gly Pro Pro Gly Pro  Gly Leu Pro 
    1010                 1015                 1020             


Ala Gly  Phe Asp Asp Met Glu  Gly Ser Gly Gly Pro  Phe Trp Ser 
    1025                 1030                 1035             


Thr Ala  Arg Ser Ala Asp Gly  Pro Gln Gly Pro Pro  Gly Leu Pro 
    1040                 1045                 1050             


Gly Leu  Lys Gly Asp Pro Gly  Val Pro Gly Leu Pro  Gly Ala Lys 
    1055                 1060                 1065             


Gly Glu  Val Gly Ala Asp Gly  Val Pro Gly Phe Pro  Gly Leu Pro 
    1070                 1075                 1080             


Gly Arg  Glu Gly Ile Ala Gly  Pro Gln Gly Pro Lys  Gly Asp Arg 
    1085                 1090                 1095             


Gly Ser  Arg Gly Glu Lys Gly  Asp Pro Gly Lys Asp  Gly Val Gly 
    1100                 1105                 1110             


Gln Pro  Gly Leu Pro Gly Pro  Pro Gly Pro Pro Gly  Pro Val Val 
    1115                 1120                 1125             


Tyr Val  Ser Glu Gln Asp Gly  Ser Val Leu Ser Val  Pro Gly Pro 
    1130                 1135                 1140             


Glu Gly  Arg Pro Gly Phe Ala  Gly Phe Pro Gly Pro  Ala Gly Pro 
    1145                 1150                 1155             


Lys Gly  Asn Leu Gly Ser Lys  Gly Glu Arg Gly Ser  Pro Gly Pro 
    1160                 1165                 1170             


Lys Gly  Glu Lys Gly Glu Pro  Gly Ser Ile Phe Ser  Pro Asp Gly 
    1175                 1180                 1185             


Gly Ala  Leu Gly Pro Ala Gln  Lys Gly Ala Lys Gly  Glu Pro Gly 
    1190                 1195                 1200             


Phe Arg  Gly Pro Pro Gly Pro  Tyr Gly Arg Pro Gly  Tyr Lys Gly 
    1205                 1210                 1215             


Glu Ile  Gly Phe Pro Gly Arg  Pro Gly Arg Pro Gly  Met Asn Gly 
    1220                 1225                 1230             


Leu Lys  Gly Glu Lys Gly Glu  Pro Gly Asp Ala Ser  Leu Gly Phe 
    1235                 1240                 1245             


Gly Met  Arg Gly Met Pro Gly  Pro Pro Gly Pro Pro  Gly Pro Pro 
    1250                 1255                 1260             


Gly Pro  Pro Gly Thr Pro Val  Tyr Asp Ser Asn Val  Phe Ala Glu 
    1265                 1270                 1275             


Ser Ser  Arg Pro Gly Pro Pro  Gly Leu Pro Gly Asn  Gln Gly Pro 
    1280                 1285                 1290             


Pro Gly  Pro Lys Gly Ala Lys  Gly Glu Val Gly Pro  Pro Gly Pro 
    1295                 1300                 1305             


Pro Gly  Gln Phe Pro Phe Asp  Phe Leu Gln Leu Glu  Ala Glu Met 
    1310                 1315                 1320             


Lys Gly  Glu Lys Gly Asp Arg  Gly Asp Ala Gly Gln  Lys Gly Glu 
    1325                 1330                 1335             


Arg Gly  Glu Pro Gly Gly Gly  Gly Phe Phe Gly Ser  Ser Leu Pro 
    1340                 1345                 1350             


Gly Pro  Pro Gly Pro Pro Gly  Pro Arg Gly Tyr Pro  Gly Ile Pro 
    1355                 1360                 1365             


Gly Pro  Lys Gly Glu Ser Ile  Arg Gly Gln Pro Gly  Pro Pro Gly 
    1370                 1375                 1380             


Pro Gln  Gly Pro Pro Gly Ile  Gly Tyr Glu Gly Arg  Gln Gly Pro 
    1385                 1390                 1395             


Pro Gly  Pro Pro Gly Pro Pro  Gly Pro Pro Ser Phe  Pro Gly Pro 
    1400                 1405                 1410             


His Arg  Gln Thr Ile Ser Val  Pro Gly Pro Pro Gly  Pro Pro Gly 
    1415                 1420                 1425             


Pro Pro  Gly Pro Pro Gly Thr  Met Gly Ala Ser Ser  Gly Val Arg 
    1430                 1435                 1440             


Leu Trp  Ala Thr Arg Gln Ala  Met Leu Gly Gln Val  His Glu Val 
    1445                 1450                 1455             


Pro Glu  Gly Trp Leu Ile Phe  Val Ala Glu Gln Glu  Glu Leu Tyr 
    1460                 1465                 1470             


Val Arg  Val Gln Asn Gly Phe  Arg Lys Val Gln Leu  Glu Ala Arg 
    1475                 1480                 1485             


Thr Pro  Leu Pro Arg Gly Thr  Asp Asn Glu Val Ala  Ala Leu Gln 
    1490                 1495                 1500             


Pro Pro  Val Val Gln Leu His  Asp Ser Asn Pro Tyr  Pro Arg Arg 
    1505                 1510                 1515             


Glu His  Pro His Pro Thr Ala  Arg Pro Trp Arg Ala  Asp Asp Ile 
    1520                 1525                 1530             


Leu Ala  Ser Pro Pro Arg Leu  Pro Glu Pro Gln Pro  Tyr Pro Gly 
    1535                 1540                 1545             


Ala Pro  His His Ser Ser Tyr  Val His Leu Arg Pro  Ala Arg Pro 
    1550                 1555                 1560             


Thr Ser  Pro Pro Ala His Ser  His Arg Asp Phe Gln  Pro Val Leu 
    1565                 1570                 1575             


His Leu  Val Ala Leu Asn Ser  Pro Leu Ser Gly Gly  Met Arg Gly 
    1580                 1585                 1590             


Ile Arg  Gly Ala Asp Phe Gln  Cys Phe Gln Gln Ala  Arg Ala Val 
    1595                 1600                 1605             


Gly Leu  Ala Gly Thr Phe Arg  Ala Phe Leu Ser Ser  Arg Leu Gln 
    1610                 1615                 1620             


Asp Leu  Tyr Ser Ile Val Arg  Arg Ala Asp Arg Ala  Ala Val Pro 
    1625                 1630                 1635             


Ile Val  Asn Leu Lys Asp Glu  Leu Leu Phe Pro Ser  Trp Glu Ala 
    1640                 1645                 1650             


Leu Phe  Ser Gly Ser Glu Gly  Pro Leu Lys Pro Gly  Ala Arg Ile 
    1655                 1660                 1665             


Phe Ser  Phe Asp Gly Lys Asp  Val Leu Arg His Pro  Thr Trp Pro 
    1670                 1675                 1680             


Gln Lys  Ser Val Trp His Gly  Ser Asp Pro Asn Gly  Arg Arg Leu 
    1685                 1690                 1695             


Thr Glu  Ser Tyr Cys Glu Thr  Trp Arg Thr Glu Ala  Pro Ser Ala 
    1700                 1705                 1710             


Thr Gly  Gln Ala Ser Ser Leu  Leu Gly Gly Arg Leu  Leu Gly Gln 
    1715                 1720                 1725             


Ser Ala  Ala Ser Cys His His  Ala Tyr Ile Val Leu  Cys Ile Glu 
    1730                 1735                 1740             


Asn Ser  Phe Met Thr Ala Ser  Lys 
    1745                 1750     


<210>  3385
<211>  615
<212>  PRT
<213>  homo sapiens

<400>  3385

Met Thr Ser Pro Ser Pro Arg Ile Gln Ile Ile Ser Thr Asp Ser Ala 
1               5                   10                  15      


Val Ala Ser Pro Gln Arg Ile Gln Gly Ser Glu Pro Ala Ser Gly Pro 
            20                  25                  30          


Leu Ser Val Phe Thr Ser Leu Asn Lys Glu Lys Ile Val Thr Asp Gln 
        35                  40                  45              


Gln Thr Gly Gln Lys Ile Gln Ile Val Thr Ala Val Asp Ala Ser Gly 
    50                  55                  60                  


Ser Pro Lys Gln Gln Phe Ile Leu Thr Ser Pro Asp Gly Ala Gly Thr 
65                  70                  75                  80  


Gly Lys Val Ile Leu Ala Ser Pro Glu Thr Ser Ser Ala Lys Gln Leu 
                85                  90                  95      


Ile Phe Thr Thr Ser Asp Asn Leu Val Pro Gly Arg Ile Gln Ile Val 
            100                 105                 110         


Thr Asp Ser Ala Ser Val Glu Arg Leu Leu Gly Lys Thr Asp Val Gln 
        115                 120                 125             


Arg Pro Gln Val Val Glu Tyr Cys Val Val Cys Gly Asp Lys Ala Ser 
    130                 135                 140                 


Gly Arg His Tyr Gly Ala Val Ser Cys Glu Gly Cys Lys Gly Phe Phe 
145                 150                 155                 160 


Lys Arg Ser Val Arg Lys Asn Leu Thr Tyr Ser Cys Arg Ser Asn Gln 
                165                 170                 175     


Asp Cys Ile Ile Asn Lys His His Arg Asn Arg Cys Gln Phe Cys Arg 
            180                 185                 190         


Leu Lys Lys Cys Leu Glu Met Gly Met Lys Met Glu Ser Val Gln Ser 
        195                 200                 205             


Glu Arg Lys Pro Phe Asp Val Gln Arg Glu Lys Pro Ser Asn Cys Ala 
    210                 215                 220                 


Ala Ser Thr Glu Lys Ile Tyr Ile Arg Lys Asp Leu Arg Ser Pro Leu 
225                 230                 235                 240 


Ile Ala Thr Pro Thr Phe Val Ala Asp Lys Asp Gly Ala Arg Gln Thr 
                245                 250                 255     


Gly Leu Leu Asp Pro Gly Met Leu Val Asn Ile Gln Gln Pro Leu Ile 
            260                 265                 270         


Arg Glu Asp Gly Thr Val Leu Leu Ala Thr Asp Ser Lys Ala Glu Thr 
        275                 280                 285             


Ser Gln Gly Ala Leu Gly Thr Leu Ala Asn Val Val Thr Ser Leu Ala 
    290                 295                 300                 


Asn Leu Ser Glu Ser Leu Asn Asn Gly Asp Thr Ser Glu Ile Gln Pro 
305                 310                 315                 320 


Glu Asp Gln Ser Ala Ser Glu Ile Thr Arg Ala Phe Asp Thr Leu Ala 
                325                 330                 335     


Lys Ala Leu Asn Thr Thr Asp Ser Ser Ser Ser Pro Ser Leu Ala Asp 
            340                 345                 350         


Gly Ile Asp Thr Ser Gly Gly Gly Ser Ile His Val Ile Ser Arg Asp 
        355                 360                 365             


Gln Ser Thr Pro Ile Ile Glu Val Glu Gly Pro Leu Leu Ser Asp Thr 
    370                 375                 380                 


His Val Thr Phe Lys Leu Thr Met Pro Ser Pro Met Pro Glu Tyr Leu 
385                 390                 395                 400 


Asn Val His Tyr Ile Cys Glu Ser Ala Ser Arg Leu Leu Phe Leu Ser 
                405                 410                 415     


Met His Trp Ala Arg Ser Ile Pro Ala Phe Gln Ala Leu Gly Gln Asp 
            420                 425                 430         


Cys Asn Thr Ser Leu Val Arg Ala Cys Trp Asn Glu Leu Phe Thr Leu 
        435                 440                 445             


Gly Leu Ala Gln Cys Ala Gln Val Met Ser Leu Ser Thr Ile Leu Ala 
    450                 455                 460                 


Ala Ile Val Asn His Leu Gln Asn Ser Ile Gln Glu Asp Lys Leu Ser 
465                 470                 475                 480 


Gly Asp Arg Ile Lys Gln Val Met Glu His Ile Trp Lys Leu Gln Glu 
                485                 490                 495     


Phe Cys Asn Ser Met Ala Lys Leu Asp Ile Asp Gly Tyr Glu Tyr Ala 
            500                 505                 510         


Tyr Leu Lys Ala Ile Val Leu Phe Ser Pro Asp His Pro Gly Leu Thr 
        515                 520                 525             


Ser Thr Ser Gln Ile Glu Lys Phe Gln Glu Lys Ala Gln Met Glu Leu 
    530                 535                 540                 


Gln Asp Tyr Val Gln Lys Thr Tyr Ser Glu Asp Thr Tyr Arg Leu Ala 
545                 550                 555                 560 


Arg Ile Leu Val Arg Leu Pro Ala Leu Arg Leu Met Ser Ser Asn Ile 
                565                 570                 575     


Thr Glu Glu Leu Phe Phe Thr Gly Leu Ile Gly Asn Val Ser Ile Asp 
            580                 585                 590         


Ser Ile Ile Pro Tyr Ile Leu Lys Met Glu Thr Ala Glu Tyr Asn Gly 
        595                 600                 605             


Gln Ile Thr Gly Ala Ser Leu 
    610                 615 


<210>  3386
<211>  198
<212>  PRT
<213>  homo sapiens

<400>  3386

Met Ser Phe Ile Phe Glu Trp Ile Tyr Asn Gly Phe Ser Ser Val Leu 
1               5                   10                  15      


Gln Phe Leu Gly Leu Tyr Lys Lys Ser Gly Lys Leu Val Phe Leu Gly 
            20                  25                  30          


Leu Asp Asn Ala Gly Lys Thr Thr Leu Leu His Met Leu Lys Asp Asp 
        35                  40                  45              


Arg Leu Gly Gln His Val Pro Thr Leu His Pro Thr Ser Glu Glu Leu 
    50                  55                  60                  


Thr Ile Ala Gly Met Thr Phe Thr Thr Phe Asp Leu Gly Gly His Glu 
65                  70                  75                  80  


Gln Ala Arg Arg Val Trp Lys Asn Tyr Leu Pro Ala Ile Asn Gly Ile 
                85                  90                  95      


Val Phe Leu Val Asp Cys Ala Asp His Ser Arg Leu Val Glu Ser Lys 
            100                 105                 110         


Val Glu Leu Asn Ala Leu Met Thr Asp Glu Thr Ile Ser Asn Val Pro 
        115                 120                 125             


Ile Leu Ile Leu Gly Asn Lys Ile Asp Arg Thr Asp Ala Ile Ser Glu 
    130                 135                 140                 


Glu Lys Leu Arg Glu Ile Phe Gly Leu Tyr Gly Gln Thr Thr Gly Lys 
145                 150                 155                 160 


Gly Asn Val Thr Leu Lys Glu Leu Asn Ala Arg Pro Met Glu Val Phe 
                165                 170                 175     


Met Cys Ser Val Leu Lys Arg Gln Gly Tyr Gly Glu Gly Phe Arg Trp 
            180                 185                 190         


Leu Ser Gln Tyr Ile Asp 
        195             


<210>  3387
<211>  252
<212>  PRT
<213>  homo sapiens

<400>  3387

Met Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala Gly Ser Gly Lys Arg 
1               5                   10                  15      


Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val Gln Ile Leu Arg Asp 
            20                  25                  30          


Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro Ser Glu Gln Glu Lys 
        35                  40                  45              


Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr Leu Gln Val Cys Asn 
    50                  55                  60                  


Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro Asp Met Leu Arg Lys 
65                  70                  75                  80  


Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile Ser Arg Arg Gly Ala Lys 
                85                  90                  95      


Ile Ser Glu Thr Ser Ser Val Glu Ser Val Met Gly Ile Lys Asn Phe 
            100                 105                 110         


Met Pro Ala Leu Glu Glu Thr Pro Phe His Ser Cys Thr Ala Gly Pro 
        115                 120                 125             


Asn Pro Thr Leu Gly Arg Pro Leu Ser Pro Lys Pro Ser Ser Pro Gly 
    130                 135                 140                 


Ser Val Leu Ala Arg Pro Ser Val Ile Cys His Thr Thr Val Thr Ala 
145                 150                 155                 160 


Leu Lys Asp Val Pro Phe Ser Leu Cys Gln Ser Val Gly Val Gly Gln 
                165                 170                 175     


Asn Thr Asp Ile Gln Gln Ile Ala Ala Lys Asn Phe Thr Asp Thr Ser 
            180                 185                 190         


Leu Met Tyr Pro Glu Asp Thr Cys Lys Ser Gly Pro Ser Thr Asn Thr 
        195                 200                 205             


Gln Ser Gly Leu Phe Asn Thr Pro Pro Pro Thr Pro Pro Asp Leu Asn 
    210                 215                 220                 


Gln Asp Phe Ser Gly Phe Gln Leu Leu Val Asp Val Ala Leu Lys Arg 
225                 230                 235                 240 


Ala Ala Glu Met Glu Leu Gln Ala Lys Leu Thr Ala 
                245                 250         


<210>  3388
<211>  553
<212>  PRT
<213>  homo sapiens

<400>  3388

Met Ala Ala Val Ser Leu Arg Leu Gly Asp Leu Val Trp Gly Lys Leu 
1               5                   10                  15      


Gly Arg Tyr Pro Pro Trp Pro Gly Lys Ile Val Asn Pro Pro Lys Asp 
            20                  25                  30          


Leu Lys Lys Pro Arg Gly Lys Lys Cys Phe Phe Val Lys Phe Phe Gly 
        35                  40                  45              


Thr Glu Asp His Ala Trp Ile Lys Val Glu Gln Leu Lys Pro Tyr His 
    50                  55                  60                  


Ala His Lys Glu Glu Met Ile Lys Ile Asn Lys Gly Lys Arg Phe Gln 
65                  70                  75                  80  


Gln Ala Val Asp Ala Val Glu Glu Phe Leu Arg Arg Ala Lys Gly Lys 
                85                  90                  95      


Asp Gln Thr Ser Ser His Asn Ser Ser Asp Asp Lys Asn Arg Arg Asn 
            100                 105                 110         


Ser Ser Glu Glu Arg Ser Arg Pro Asn Ser Gly Asp Glu Lys Arg Lys 
        115                 120                 125             


Leu Ser Leu Ser Glu Gly Lys Val Lys Lys Asn Met Gly Glu Gly Lys 
    130                 135                 140                 


Lys Arg Val Ser Ser Gly Ser Ser Glu Arg Gly Ser Lys Ser Pro Leu 
145                 150                 155                 160 


Lys Arg Ala Gln Glu Gln Ser Pro Arg Lys Arg Gly Arg Pro Pro Lys 
                165                 170                 175     


Asp Glu Lys Asp Leu Thr Ile Pro Glu Ser Ser Thr Val Lys Gly Met 
            180                 185                 190         


Met Ala Gly Pro Met Ala Ala Phe Lys Trp Gln Pro Thr Ala Ser Glu 
        195                 200                 205             


Pro Val Lys Asp Ala Asp Pro His Phe His His Phe Leu Leu Ser Gln 
    210                 215                 220                 


Thr Glu Lys Pro Ala Val Cys Tyr Gln Ala Ile Thr Lys Lys Leu Lys 
225                 230                 235                 240 


Ile Cys Glu Glu Glu Thr Gly Ser Thr Ser Ile Gln Ala Ala Asp Ser 
                245                 250                 255     


Thr Ala Val Asn Gly Ser Ile Thr Pro Thr Asp Lys Lys Ile Gly Phe 
            260                 265                 270         


Leu Gly Leu Gly Leu Met Gly Ser Gly Ile Val Ser Asn Leu Leu Lys 
        275                 280                 285             


Met Gly His Thr Val Thr Val Trp Asn Arg Thr Ala Glu Lys Cys Asp 
    290                 295                 300                 


Leu Phe Ile Gln Glu Gly Ala Arg Leu Gly Arg Thr Pro Ala Glu Val 
305                 310                 315                 320 


Val Ser Thr Cys Asp Ile Thr Phe Ala Cys Val Ser Asp Pro Lys Ala 
                325                 330                 335     


Ala Lys Asp Leu Val Leu Gly Pro Ser Gly Val Leu Gln Gly Ile Arg 
            340                 345                 350         


Pro Gly Lys Cys Tyr Val Asp Met Ser Thr Val Asp Ala Asp Thr Val 
        355                 360                 365             


Thr Glu Leu Ala Gln Val Ile Val Ser Arg Gly Gly Arg Phe Leu Glu 
    370                 375                 380                 


Ala Pro Val Ser Gly Asn Gln Gln Leu Ser Asn Asp Gly Met Leu Val 
385                 390                 395                 400 


Ile Leu Ala Ala Gly Asp Arg Gly Leu Tyr Glu Asp Cys Ser Ser Cys 
                405                 410                 415     


Phe Gln Ala Met Gly Lys Thr Ser Phe Phe Leu Gly Glu Val Gly Asn 
            420                 425                 430         


Ala Ala Lys Met Met Leu Ile Val Asn Met Val Gln Gly Ser Phe Met 
        435                 440                 445             


Ala Thr Ile Ala Glu Gly Leu Thr Leu Ala Gln Val Thr Gly Gln Ser 
    450                 455                 460                 


Gln Gln Thr Leu Leu Asp Ile Leu Asn Gln Gly Gln Leu Ala Ser Ile 
465                 470                 475                 480 


Phe Leu Asp Gln Lys Cys Gln Asn Ile Leu Gln Gly Asn Phe Lys Pro 
                485                 490                 495     


Asp Phe Tyr Leu Lys Tyr Ile Gln Lys Asp Leu Arg Leu Ala Ile Ala 
            500                 505                 510         


Leu Gly Asp Ala Val Asn His Pro Thr Pro Met Ala Ala Ala Ala Asn 
        515                 520                 525             


Glu Val Tyr Lys Arg Ala Lys Ala Leu Asp Gln Ser Asp Asn Asp Met 
    530                 535                 540                 


Ser Ala Val Tyr Arg Ala Tyr Ile His 
545                 550             


<210>  3389
<211>  433
<212>  PRT
<213>  homo sapiens

<400>  3389

Met Gln Arg Met Ile Gln Gln Phe Ala Ala Glu Tyr Thr Ser Lys Asn 
1               5                   10                  15      


Ser Ser Thr Gln Asp Pro Ser Gln Pro Asn Ser Thr Lys Asn Gln Ser 
            20                  25                  30          


Leu Pro Lys Ala Ser Pro Val Thr Thr Ser Pro Thr Ala Ala Thr Thr 
        35                  40                  45              


Gln Asn Pro Val Leu Ser Lys Leu Leu Met Ala Asp Gln Asp Ser Pro 
    50                  55                  60                  


Leu Asp Leu Thr Val Arg Lys Ser Gln Ser Glu Pro Ser Glu Gln Asp 
65                  70                  75                  80  


Gly Val Leu Asp Leu Ser Thr Lys Lys Ser Pro Cys Ala Gly Ser Thr 
                85                  90                  95      


Ser Leu Ser His Ser Pro Gly Cys Ser Ser Thr Gln Gly Asn Gly Arg 
            100                 105                 110         


Pro Gly Arg Pro Ser Gln Tyr Arg Pro Asp Gly Leu Arg Ser Gly Asp 
        115                 120                 125             


Gly Val Pro Pro Arg Ser Leu Gln Asp Gly Thr Arg Glu Gly Phe Gly 
    130                 135                 140                 


His Ser Thr Ser Leu Lys Val Pro Leu Ala Arg Ser Leu Gln Ile Ser 
145                 150                 155                 160 


Glu Glu Leu Leu Ser Arg Asn Gln Leu Ser Thr Ala Ala Ser Leu Gly 
                165                 170                 175     


Pro Ser Gly Leu Gln Asn His Gly Gln His Leu Ile Leu Ser Arg Glu 
            180                 185                 190         


Ala Ser Trp Ala Lys Pro His Tyr Glu Phe Asn Leu Ser Arg Met Lys 
        195                 200                 205             


Phe Arg Gly Asn Gly Ala Leu Ser Asn Ile Ser Asp Leu Pro Phe Leu 
    210                 215                 220                 


Ala Glu Asn Ser Ala Phe Pro Lys Met Ala Leu Gln Ala Lys Gln Asp 
225                 230                 235                 240 


Gly Lys Lys Asp Val Ser His Ser Ser Pro Val Asp Leu Lys Ile Pro 
                245                 250                 255     


Gln Val Arg Gly Met Asp Leu Ser Trp Glu Ser Arg Thr Gly Asp Gln 
            260                 265                 270         


Tyr Ser Tyr Ser Ser Leu Val Met Gly Ser Gln Thr Glu Ser Ala Leu 
        275                 280                 285             


Ser Lys Lys Leu Arg Ala Ile Leu Pro Lys Gln Ser Arg Lys Ser Met 
    290                 295                 300                 


Leu Asp Ala Gly Pro Asp Ser Trp Gly Ser Asp Ala Glu Gln Ser Thr 
305                 310                 315                 320 


Ser Gly Gln Pro Tyr Pro Thr Ser Asp Gln Glu Gly Asp Pro Gly Ser 
                325                 330                 335     


Lys Gln Pro Arg Lys Lys Arg Gly Arg Tyr Arg Gln Tyr Asn Ser Glu 
            340                 345                 350         


Ile Leu Glu Glu Ala Ile Ser Val Val Met Ser Gly Lys Met Ser Val 
        355                 360                 365             


Ser Lys Ala Gln Ser Ile Tyr Gly Ile Pro His Ser Thr Leu Glu Tyr 
    370                 375                 380                 


Lys Val Lys Glu Arg Leu Gly Thr Leu Lys Asn Pro Pro Lys Lys Lys 
385                 390                 395                 400 


Met Lys Leu Met Arg Ser Glu Gly Pro Asp Val Ser Val Lys Ile Glu 
                405                 410                 415     


Leu Asp Pro Gln Gly Glu Ala Ala Gln Ser Ala Asn Glu Ser Lys Asn 
            420                 425                 430         


Glu 
    


<210>  3390
<211>  1439
<212>  PRT
<213>  homo sapiens

<400>  3390

Met Ala Thr Leu Ala Cys Arg Val Gln Phe Leu Asp Asp Thr Asp Pro 
1               5                   10                  15      


Phe Asn Ser Thr Asn Phe Pro Glu Pro Ser Arg Pro Pro Leu Phe Thr 
            20                  25                  30          


Phe Arg Glu Asp Leu Ala Leu Gly Thr Gln Leu Ala Gly Val His Arg 
        35                  40                  45              


Leu Leu Gln Ala Pro His Lys Leu Asp Asp Cys Thr Leu Gln Leu Ser 
    50                  55                  60                  


His Asn Gly Ala Tyr Leu Asp Leu Glu Ala Thr Leu Ala Glu Gln Arg 
65                  70                  75                  80  


Asp Glu Leu Glu Gly Phe Gln Asp Asp Ala Gly Arg Gly Lys Lys His 
                85                  90                  95      


Ser Ile Ile Leu Arg Thr Gln Leu Ser Val Arg Val His Ala Cys Ile 
            100                 105                 110         


Glu Lys Leu Tyr Asn Ser Ser Gly Arg Asp Leu Arg Arg Ala Leu Phe 
        115                 120                 125             


Ser Leu Lys Gln Ile Phe Gln Asp Asp Lys Asp Leu Val His Glu Phe 
    130                 135                 140                 


Val Val Ala Glu Gly Leu Thr Cys Leu Ile Lys Val Gly Ala Glu Ala 
145                 150                 155                 160 


Asp Gln Asn Tyr Gln Asn Tyr Ile Leu Arg Ala Leu Gly Gln Ile Met 
                165                 170                 175     


Leu Tyr Val Asp Gly Met Asn Gly Val Ile Asn Arg Asn Glu Thr Ile 
            180                 185                 190         


Gln Trp Leu Tyr Thr Leu Ile Gly Ser Lys Phe Arg Leu Val Val Lys 
        195                 200                 205             


Thr Ala Leu Lys Leu Leu Leu Val Phe Val Glu Tyr Ser Glu Ser Asn 
    210                 215                 220                 


Ala Pro Leu Leu Ile Gln Ala Val Thr Ala Val Asp Thr Lys Arg Gly 
225                 230                 235                 240 


Val Lys Pro Trp Ser Asn Ile Met Glu Ile Leu Glu Glu Lys Asp Gly 
                245                 250                 255     


Val Asp Thr Glu Leu Leu Val Tyr Ala Met Thr Leu Val Asn Lys Thr 
            260                 265                 270         


Leu Ser Gly Leu Pro Asp Gln Asp Thr Phe Tyr Asp Val Val Asp Cys 
        275                 280                 285             


Leu Glu Glu Leu Gly Ile Ala Ala Val Ser Gln Arg His Leu Asn Lys 
    290                 295                 300                 


Lys Gly Thr Asp Leu Asp Leu Val Glu Gln Leu Asn Ile Tyr Glu Val 
305                 310                 315                 320 


Ala Leu Arg His Glu Asp Gly Asp Glu Thr Thr Glu Pro Pro Pro Ser 
                325                 330                 335     


Gly Cys Arg Asp Arg Arg Arg Ala Ser Val Cys Ser Ser Gly Gly Gly 
            340                 345                 350         


Glu His Arg Gly Leu Asp Arg Arg Arg Ser Arg Arg His Ser Val Gln 
        355                 360                 365             


Ser Ile Lys Ser Thr Leu Ser Ala Pro Thr Ser Pro Cys Ser Gln Ser 
    370                 375                 380                 


Ala Pro Ser Phe Lys Pro Asn Gln Val Arg Asp Leu Arg Glu Lys Tyr 
385                 390                 395                 400 


Ser Asn Phe Gly Asn Asn Ser Tyr His Ser Ser Arg Pro Ser Ser Gly 
                405                 410                 415     


Ser Ser Val Pro Thr Thr Pro Thr Ser Ser Val Ser Pro Pro Gln Glu 
            420                 425                 430         


Ala Arg Leu Glu Arg Ser Ser Pro Ser Gly Leu Leu Thr Ser Ser Phe 
        435                 440                 445             


Arg Gln His Gln Glu Ser Leu Ala Ala Glu Arg Glu Arg Arg Arg Gln 
    450                 455                 460                 


Glu Arg Glu Glu Arg Leu Gln Arg Ile Glu Arg Glu Glu Arg Asn Lys 
465                 470                 475                 480 


Phe Ser Arg Asp Tyr Leu Asp Lys Arg Glu Glu Gln Arg Gln Ala Arg 
                485                 490                 495     


Glu Glu Arg Tyr Lys Tyr Leu Glu Gln Leu Ala Ala Glu Glu His Glu 
            500                 505                 510         


Lys Glu Leu Arg Ser Arg Ser Val Ser Arg Gly Arg Ala Asp Leu Ser 
        515                 520                 525             


Leu Asp Leu Thr Ser Pro Ala Ala Pro Ala Cys Leu Ala Pro Leu Ser 
    530                 535                 540                 


His Ser Pro Ser Ser Ser Asp Ser Gln Glu Ala Leu Thr Val Ser Ala 
545                 550                 555                 560 


Ser Ser Pro Gly Thr Pro His His Pro Gln Ala Ser Ala Gly Asp Pro 
                565                 570                 575     


Glu Pro Glu Ser Glu Ala Glu Pro Glu Ala Glu Ala Gly Ala Gly Gln 
            580                 585                 590         


Val Ala Asp Glu Ala Gly Gln Asp Ile Ala Ser Ala His Glu Gly Ala 
        595                 600                 605             


Glu Thr Glu Val Glu Gln Ala Leu Glu Gln Glu Pro Glu Glu Arg Ala 
    610                 615                 620                 


Ser Leu Ser Glu Lys Glu Arg Gln Asn Glu Gly Val Asn Glu Arg Asp 
625                 630                 635                 640 


Asn Cys Ser Ala Ser Ser Val Ser Ser Ser Ser Ser Thr Leu Glu Arg 
                645                 650                 655     


Glu Glu Lys Glu Asp Lys Leu Ser Arg Asp Arg Thr Thr Gly Leu Trp 
            660                 665                 670         


Pro Ala Gly Val Gln Asp Ala Gly Val Asn Gly Gln Cys Gly Asp Ile 
        675                 680                 685             


Leu Thr Asn Lys Arg Phe Met Leu Asp Met Leu Tyr Ala His Asn Arg 
    690                 695                 700                 


Lys Ser Pro Asp Asp Glu Glu Lys Gly Asp Gly Glu Ala Gly Arg Thr 
705                 710                 715                 720 


Gln Gln Glu Ala Glu Ala Val Ala Ser Leu Ala Thr Arg Ile Ser Thr 
                725                 730                 735     


Leu Gln Ala Asn Ser Gln Thr Gln Asp Glu Ser Val Arg Arg Val Asp 
            740                 745                 750         


Val Gly Cys Leu Asp Asn Arg Gly Ser Val Lys Ala Phe Ala Glu Lys 
        755                 760                 765             


Phe Asn Ser Gly Asp Leu Gly Arg Gly Ser Ile Ser Pro Asp Ala Glu 
    770                 775                 780                 


Pro Asn Asp Lys Val Pro Glu Thr Ala Pro Val Gln Pro Lys Thr Glu 
785                 790                 795                 800 


Ser Asp Tyr Ile Trp Asp Gln Leu Met Ala Asn Pro Arg Glu Leu Arg 
                805                 810                 815     


Ile Gln Asp Met Asp Phe Thr Asp Leu Gly Glu Glu Asp Asp Ile Asp 
            820                 825                 830         


Val Leu Asp Val Asp Leu Gly His Arg Glu Ala Pro Gly Pro Pro Pro 
        835                 840                 845             


Pro Pro Pro Pro Thr Phe Leu Gly Leu Pro Pro Pro Pro Pro Pro Pro 
    850                 855                 860                 


Leu Leu Asp Ser Ile Pro Pro Pro Pro Val Pro Gly Asn Leu Leu Val 
865                 870                 875                 880 


Pro Pro Pro Pro Val Phe Asn Ala Pro Gln Gly Leu Gly Trp Ser Gln 
                885                 890                 895     


Val Pro Arg Gly Gln Pro Thr Phe Thr Lys Lys Lys Lys Thr Ile Arg 
            900                 905                 910         


Leu Phe Trp Asn Glu Val Arg Pro Phe Asp Trp Pro Cys Lys Asn Asn 
        915                 920                 925             


Arg Arg Cys Arg Glu Phe Leu Trp Ser Lys Leu Glu Pro Ile Lys Val 
    930                 935                 940                 


Asp Thr Ser Arg Leu Glu His Leu Phe Glu Ser Lys Ser Lys Glu Leu 
945                 950                 955                 960 


Ser Val Ser Lys Lys Thr Ala Ala Asp Gly Lys Arg Gln Glu Ile Ile 
                965                 970                 975     


Val Leu Asp Ser Lys Arg Ser Asn Ala Ile Asn Ile Gly Leu Thr Val 
            980                 985                 990         


Leu Pro Pro Pro Arg Thr Ile Lys  Ile Ala Ile Leu Asn  Phe Asp Glu 
        995                 1000                 1005             


Tyr Ala  Leu Asn Lys Glu Gly  Ile Glu Lys Ile Leu  Thr Met Ile 
    1010                 1015                 1020             


Pro Thr  Asp Glu Glu Lys Gln  Lys Ile Gln Glu Ala  Gln Leu Ala 
    1025                 1030                 1035             


Asn Pro  Glu Ile Pro Leu Gly  Ser Ala Glu Gln Phe  Leu Leu Thr 
    1040                 1045                 1050             


Leu Ser  Ser Ile Ser Glu Leu  Ser Ala Arg Leu His  Leu Trp Ala 
    1055                 1060                 1065             


Phe Lys  Met Asp Tyr Glu Thr  Thr Glu Lys Glu Val  Ala Glu Pro 
    1070                 1075                 1080             


Leu Leu  Asp Leu Lys Glu Gly  Ile Asp Gln Leu Glu  Asn Asn Lys 
    1085                 1090                 1095             


Thr Leu  Gly Phe Ile Leu Ser  Thr Leu Leu Ala Ile  Gly Asn Phe 
    1100                 1105                 1110             


Leu Asn  Gly Thr Asn Ala Lys  Ala Phe Glu Leu Ser  Tyr Leu Glu 
    1115                 1120                 1125             


Lys Val  Pro Glu Val Lys Asp  Thr Val His Lys Gln  Ser Leu Leu 
    1130                 1135                 1140             


His His  Val Cys Thr Met Val  Val Glu Asn Phe Pro  Asp Ser Ser 
    1145                 1150                 1155             


Asp Leu  Tyr Ser Glu Ile Gly  Ala Ile Thr Arg Ser  Ala Lys Val 
    1160                 1165                 1170             


Asp Phe  Asp Gln Leu Gln Asp  Asn Leu Cys Gln Met  Glu Arg Arg 
    1175                 1180                 1185             


Cys Lys  Ala Ser Trp Asp His  Leu Lys Ala Ile Ala  Lys His Glu 
    1190                 1195                 1200             


Met Lys  Pro Val Leu Lys Gln  Arg Met Ser Glu Phe  Leu Lys Asp 
    1205                 1210                 1215             


Cys Ala  Glu Arg Ile Ile Ile  Leu Lys Ile Val His  Arg Arg Ile 
    1220                 1225                 1230             


Ile Asn  Arg Phe His Ser Phe  Leu Leu Phe Met Gly  His Pro Pro 
    1235                 1240                 1245             


Tyr Ala  Ile Arg Glu Val Asn  Ile Asn Lys Phe Cys  Arg Ile Ile 
    1250                 1255                 1260             


Ser Glu  Phe Ala Leu Glu Tyr  Arg Thr Thr Arg Glu  Arg Val Leu 
    1265                 1270                 1275             


Gln Gln  Lys Gln Lys Arg Ala  Asn His Arg Glu Arg  Asn Lys Thr 
    1280                 1285                 1290             


Arg Gly  Lys Met Ile Thr Asp  Ser Gly Lys Phe Ser  Gly Ser Ser 
    1295                 1300                 1305             


Pro Ala  Pro Pro Ser Gln Pro  Gln Gly Leu Ser Tyr  Ala Glu Asp 
    1310                 1315                 1320             


Ala Ala  Glu His Glu Asn Met  Lys Ala Val Leu Lys  Thr Ser Ser 
    1325                 1330                 1335             


Pro Ser  Val Glu Asp Ala Thr  Pro Ala Leu Gly Val  Arg Thr Arg 
    1340                 1345                 1350             


Ser Arg  Ala Ser Arg Gly Ser  Thr Ser Ser Trp Thr  Met Gly Thr 
    1355                 1360                 1365             


Asp Asp  Ser Pro Asn Val Thr  Asp Asp Ala Ala Asp  Glu Ile Met 
    1370                 1375                 1380             


Asp Arg  Ile Val Lys Ser Ala  Thr Gln Val Pro Ser  Gln Arg Val 
    1385                 1390                 1395             


Val Pro  Arg Glu Arg Lys Arg  Ser Arg Ala Asn Arg  Lys Ser Leu 
    1400                 1405                 1410             


Arg Arg  Thr Leu Lys Ser Gly  Leu Thr Pro Glu Glu  Ala Arg Ala 
    1415                 1420                 1425             


Leu Gly  Leu Val Gly Thr Ser  Glu Leu Gln Leu 
    1430                 1435                 


<210>  3391
<211>  1036
<212>  PRT
<213>  homo sapiens

<400>  3391

Met Ala Ser Ser Val Gly Asn Val Ala Asp Ser Thr Gly Leu Ala Glu 
1               5                   10                  15      


Leu Ala His Arg Glu Tyr Gln Ala Gly Asp Phe Glu Ala Ala Glu Arg 
            20                  25                  30          


His Cys Met Gln Leu Trp Arg Gln Glu Pro Asp Asn Thr Gly Val Leu 
        35                  40                  45              


Leu Leu Leu Ser Ser Ile His Phe Gln Cys Arg Arg Leu Asp Arg Ser 
    50                  55                  60                  


Ala His Phe Ser Thr Leu Ala Ile Lys Gln Asn Pro Leu Leu Ala Glu 
65                  70                  75                  80  


Ala Tyr Ser Asn Leu Gly Asn Val Tyr Lys Glu Arg Gly Gln Leu Gln 
                85                  90                  95      


Glu Ala Ile Glu His Tyr Arg His Ala Leu Arg Leu Lys Pro Asp Phe 
            100                 105                 110         


Ile Asp Gly Tyr Ile Asn Leu Ala Ala Ala Leu Val Ala Ala Gly Asp 
        115                 120                 125             


Met Glu Gly Ala Val Gln Ala Tyr Val Ser Ala Leu Gln Tyr Asn Pro 
    130                 135                 140                 


Asp Leu Tyr Cys Val Arg Ser Asp Leu Gly Asn Leu Leu Lys Ala Leu 
145                 150                 155                 160 


Gly Arg Leu Glu Glu Ala Lys Ala Cys Tyr Leu Lys Ala Ile Glu Thr 
                165                 170                 175     


Gln Pro Asn Phe Ala Val Ala Trp Ser Asn Leu Gly Cys Val Phe Asn 
            180                 185                 190         


Ala Gln Gly Glu Ile Trp Leu Ala Ile His His Phe Glu Lys Ala Val 
        195                 200                 205             


Thr Leu Asp Pro Asn Phe Leu Asp Ala Tyr Ile Asn Leu Gly Asn Val 
    210                 215                 220                 


Leu Lys Glu Ala Arg Ile Phe Asp Arg Ala Val Ala Ala Tyr Leu Arg 
225                 230                 235                 240 


Ala Leu Ser Leu Ser Pro Asn His Ala Val Val His Gly Asn Leu Ala 
                245                 250                 255     


Cys Val Tyr Tyr Glu Gln Gly Leu Ile Asp Leu Ala Ile Asp Thr Tyr 
            260                 265                 270         


Arg Arg Ala Ile Glu Leu Gln Pro His Phe Pro Asp Ala Tyr Cys Asn 
        275                 280                 285             


Leu Ala Asn Ala Leu Lys Glu Lys Gly Ser Val Ala Glu Ala Glu Asp 
    290                 295                 300                 


Cys Tyr Asn Thr Ala Leu Arg Leu Cys Pro Thr His Ala Asp Ser Leu 
305                 310                 315                 320 


Asn Asn Leu Ala Asn Ile Lys Arg Glu Gln Gly Asn Ile Glu Glu Ala 
                325                 330                 335     


Val Arg Leu Tyr Arg Lys Ala Leu Glu Val Phe Pro Glu Phe Ala Ala 
            340                 345                 350         


Ala His Ser Asn Leu Ala Ser Val Leu Gln Gln Gln Gly Lys Leu Gln 
        355                 360                 365             


Glu Ala Leu Met His Tyr Lys Glu Ala Ile Arg Ile Ser Pro Thr Phe 
    370                 375                 380                 


Ala Asp Ala Tyr Ser Asn Met Gly Asn Thr Leu Lys Glu Met Gln Asp 
385                 390                 395                 400 


Val Gln Gly Ala Leu Gln Cys Tyr Thr Arg Ala Ile Gln Ile Asn Pro 
                405                 410                 415     


Ala Phe Ala Asp Ala His Ser Asn Leu Ala Ser Ile His Lys Asp Ser 
            420                 425                 430         


Gly Asn Ile Pro Glu Ala Ile Ala Ser Tyr Arg Thr Ala Leu Lys Leu 
        435                 440                 445             


Lys Pro Asp Phe Pro Asp Ala Tyr Cys Asn Leu Ala His Cys Leu Gln 
    450                 455                 460                 


Ile Val Cys Asp Trp Thr Asp Tyr Asp Glu Arg Met Lys Lys Leu Val 
465                 470                 475                 480 


Ser Ile Val Ala Asp Gln Leu Glu Lys Asn Arg Leu Pro Ser Val His 
                485                 490                 495     


Pro His His Ser Met Leu Tyr Pro Leu Ser His Gly Phe Arg Lys Ala 
            500                 505                 510         


Ile Ala Glu Arg His Gly Asn Leu Cys Leu Asp Lys Ile Asn Val Leu 
        515                 520                 525             


His Lys Pro Pro Tyr Glu His Pro Lys Asp Leu Lys Leu Ser Asp Gly 
    530                 535                 540                 


Arg Leu Arg Val Gly Tyr Val Ser Ser Asp Phe Gly Asn His Pro Thr 
545                 550                 555                 560 


Ser His Leu Met Gln Ser Ile Pro Gly Met His Asn Pro Asp Lys Phe 
                565                 570                 575     


Glu Val Phe Cys Tyr Ala Leu Ser Pro Asp Asp Gly Thr Asn Phe Arg 
            580                 585                 590         


Val Lys Val Met Ala Glu Ala Asn His Phe Ile Asp Leu Ser Gln Ile 
        595                 600                 605             


Pro Cys Asn Gly Lys Ala Ala Asp Arg Ile His Gln Asp Gly Ile His 
    610                 615                 620                 


Ile Leu Val Asn Met Asn Gly Tyr Thr Lys Gly Ala Arg Asn Glu Leu 
625                 630                 635                 640 


Phe Ala Leu Arg Pro Ala Pro Ile Gln Ala Met Trp Leu Gly Tyr Pro 
                645                 650                 655     


Gly Thr Ser Gly Ala Leu Phe Met Asp Tyr Ile Ile Thr Asp Gln Glu 
            660                 665                 670         


Thr Ser Pro Ala Glu Val Ala Glu Gln Tyr Ser Glu Lys Leu Ala Tyr 
        675                 680                 685             


Met Pro His Thr Phe Phe Ile Gly Asp His Ala Asn Met Phe Pro His 
    690                 695                 700                 


Leu Lys Lys Lys Ala Val Ile Asp Phe Lys Ser Asn Gly His Ile Tyr 
705                 710                 715                 720 


Asp Asn Arg Ile Val Leu Asn Gly Ile Asp Leu Lys Ala Phe Leu Asp 
                725                 730                 735     


Ser Leu Pro Asp Val Lys Ile Val Lys Met Lys Cys Pro Asp Gly Gly 
            740                 745                 750         


Asp Asn Ala Asp Ser Ser Asn Thr Ala Leu Asn Met Pro Val Ile Pro 
        755                 760                 765             


Met Asn Thr Ile Ala Glu Ala Val Ile Glu Met Ile Asn Arg Gly Gln 
    770                 775                 780                 


Ile Gln Ile Thr Ile Asn Gly Phe Ser Ile Ser Asn Gly Leu Ala Thr 
785                 790                 795                 800 


Thr Gln Ile Asn Asn Lys Ala Ala Thr Gly Glu Glu Val Pro Arg Thr 
                805                 810                 815     


Ile Ile Val Thr Thr Arg Ser Gln Tyr Gly Leu Pro Glu Asp Ala Ile 
            820                 825                 830         


Val Tyr Cys Asn Phe Asn Gln Leu Tyr Lys Ile Asp Pro Ser Thr Leu 
        835                 840                 845             


Gln Met Trp Ala Asn Ile Leu Lys Arg Val Pro Asn Ser Val Leu Trp 
    850                 855                 860                 


Leu Leu Arg Phe Pro Ala Val Gly Glu Pro Asn Ile Gln Gln Tyr Ala 
865                 870                 875                 880 


Gln Asn Met Gly Leu Pro Gln Asn Arg Ile Ile Phe Ser Pro Val Ala 
                885                 890                 895     


Pro Lys Glu Glu His Val Arg Arg Gly Gln Leu Ala Asp Val Cys Leu 
            900                 905                 910         


Asp Thr Pro Leu Cys Asn Gly His Thr Thr Gly Met Asp Val Leu Trp 
        915                 920                 925             


Ala Gly Thr Pro Met Val Thr Met Pro Gly Glu Thr Leu Ala Ser Arg 
    930                 935                 940                 


Val Ala Ala Ser Gln Leu Thr Cys Leu Gly Cys Leu Glu Leu Ile Ala 
945                 950                 955                 960 


Lys Asn Arg Gln Glu Tyr Glu Asp Ile Ala Val Lys Leu Gly Thr Asp 
                965                 970                 975     


Leu Glu Tyr Leu Lys Lys Val Arg Gly Lys Val Trp Lys Gln Arg Ile 
            980                 985                 990         


Ser Ser Pro Leu Phe Asn Thr Lys  Gln Tyr Thr Met Glu  Leu Glu Arg 
        995                 1000                 1005             


Leu Tyr  Leu Gln Met Trp Glu  His Tyr Ala Ala Gly  Asn Lys Pro 
    1010                 1015                 1020             


Asp His  Met Ile Lys Pro Val  Glu Val Thr Glu Ser  Ala 
    1025                 1030                 1035     


<210>  3392
<211>  352
<212>  PRT
<213>  homo sapiens

<400>  3392

Met Lys Pro Ala Leu Leu Glu Val Met Arg Met Asn Arg Ile Cys Arg 
1               5                   10                  15      


Met Val Leu Ala Thr Cys Leu Gly Ser Phe Ile Leu Val Ile Phe Tyr 
            20                  25                  30          


Phe Gln Ser Met Leu His Pro Val Met Arg Arg Asn Pro Phe Gly Val 
        35                  40                  45              


Asp Ile Cys Cys Arg Lys Gly Ser Arg Ser Pro Leu Gln Glu Leu Tyr 
    50                  55                  60                  


Asn Pro Ile Gln Leu Glu Leu Ser Asn Thr Ala Val Leu His Gln Met 
65                  70                  75                  80  


Arg Arg Asp Gln Val Thr Asp Thr Cys Arg Ala Asn Ser Ala Thr Ser 
                85                  90                  95      


Arg Lys Arg Arg Val Leu Thr Pro Asn Asp Leu Lys His Leu Val Val 
            100                 105                 110         


Asp Glu Asp His Glu Leu Ile Tyr Cys Tyr Val Pro Lys Val Ala Cys 
        115                 120                 125             


Thr Asn Trp Lys Arg Leu Met Met Val Leu Thr Gly Arg Gly Lys Tyr 
    130                 135                 140                 


Ser Asp Pro Met Glu Ile Pro Ala Asn Glu Ala His Val Ser Ala Asn 
145                 150                 155                 160 


Leu Lys Thr Leu Asn Gln Tyr Ser Ile Pro Glu Ile Asn His Arg Leu 
                165                 170                 175     


Lys Ser Tyr Met Lys Phe Leu Phe Val Arg Glu Pro Phe Glu Arg Leu 
            180                 185                 190         


Val Ser Ala Tyr Arg Asn Lys Phe Thr Gln Lys Tyr Asn Ile Ser Phe 
        195                 200                 205             


His Lys Arg Tyr Gly Thr Lys Ile Ile Lys Arg Gln Arg Lys Asn Ala 
    210                 215                 220                 


Thr Gln Glu Ala Leu Arg Lys Gly Asp Asp Val Lys Phe Glu Glu Phe 
225                 230                 235                 240 


Val Ala Tyr Leu Ile Asp Pro His Thr Gln Arg Glu Glu Pro Phe Asn 
                245                 250                 255     


Glu His Trp Gln Thr Val Tyr Ser Leu Cys His Pro Cys His Ile His 
            260                 265                 270         


Tyr Asp Leu Val Gly Lys Tyr Glu Thr Leu Glu Glu Asp Ser Asn Tyr 
        275                 280                 285             


Val Leu Gln Leu Ala Gly Val Gly Ser Tyr Leu Lys Phe Pro Thr Tyr 
    290                 295                 300                 


Ala Lys Ser Thr Arg Thr Thr Asp Glu Met Thr Thr Glu Phe Phe Gln 
305                 310                 315                 320 


Asn Ile Ser Ser Glu His Gln Thr Gln Leu Tyr Glu Val Tyr Lys Leu 
                325                 330                 335     


Asp Phe Leu Met Phe Asn Tyr Ser Val Pro Ser Tyr Leu Lys Leu Glu 
            340                 345                 350         


<210>  3393
<211>  457
<212>  PRT
<213>  homo sapiens

<400>  3393

Met Thr Thr Asp Glu Gly Ala Lys Asn Asn Glu Glu Ser Pro Thr Ala 
1               5                   10                  15      


Thr Val Ala Glu Gln Gly Glu Asp Ile Thr Ser Lys Lys Asp Arg Gly 
            20                  25                  30          


Val Leu Lys Ile Val Lys Arg Val Gly Asn Gly Glu Glu Thr Pro Met 
        35                  40                  45              


Ile Gly Asp Lys Val Tyr Val His Tyr Lys Gly Lys Leu Ser Asn Gly 
    50                  55                  60                  


Lys Lys Phe Asp Ser Ser His Asp Arg Asn Glu Pro Phe Val Phe Ser 
65                  70                  75                  80  


Leu Gly Lys Gly Gln Val Ile Lys Ala Trp Asp Ile Gly Val Ala Thr 
                85                  90                  95      


Met Lys Lys Gly Glu Ile Cys His Leu Leu Cys Lys Pro Glu Tyr Ala 
            100                 105                 110         


Tyr Gly Ser Ala Gly Ser Leu Pro Lys Ile Pro Ser Asn Ala Thr Leu 
        115                 120                 125             


Phe Phe Glu Ile Glu Leu Leu Asp Phe Lys Gly Glu Asp Leu Phe Glu 
    130                 135                 140                 


Asp Gly Gly Ile Ile Arg Arg Thr Lys Arg Lys Gly Glu Gly Tyr Ser 
145                 150                 155                 160 


Asn Pro Asn Glu Gly Ala Thr Val Glu Ile His Leu Glu Gly Arg Cys 
                165                 170                 175     


Gly Gly Arg Met Phe Asp Cys Arg Asp Val Ala Phe Thr Val Gly Glu 
            180                 185                 190         


Gly Glu Asp His Asp Ile Pro Ile Gly Ile Asp Lys Ala Leu Glu Lys 
        195                 200                 205             


Met Gln Arg Glu Glu Gln Cys Ile Leu Tyr Leu Gly Pro Arg Tyr Gly 
    210                 215                 220                 


Phe Gly Glu Ala Gly Lys Pro Lys Phe Gly Ile Glu Pro Asn Ala Glu 
225                 230                 235                 240 


Leu Ile Tyr Glu Val Thr Leu Lys Ser Phe Glu Lys Ala Lys Glu Ser 
                245                 250                 255     


Trp Glu Met Asp Thr Lys Glu Lys Leu Glu Gln Ala Ala Ile Val Lys 
            260                 265                 270         


Glu Lys Gly Thr Val Tyr Phe Lys Gly Gly Lys Tyr Met Gln Ala Val 
        275                 280                 285             


Ile Gln Tyr Gly Lys Ile Val Ser Trp Leu Glu Met Glu Tyr Gly Leu 
    290                 295                 300                 


Ser Glu Lys Glu Ser Lys Ala Ser Glu Ser Phe Leu Leu Ala Ala Phe 
305                 310                 315                 320 


Leu Asn Leu Ala Met Cys Tyr Leu Lys Leu Arg Glu Tyr Thr Lys Ala 
                325                 330                 335     


Val Glu Cys Cys Asp Lys Ala Leu Gly Leu Asp Ser Ala Asn Glu Lys 
            340                 345                 350         


Gly Leu Tyr Arg Arg Gly Glu Ala Gln Leu Leu Met Asn Glu Phe Glu 
        355                 360                 365             


Ser Ala Lys Gly Asp Phe Glu Lys Val Leu Glu Val Asn Pro Gln Asn 
    370                 375                 380                 


Lys Ala Ala Arg Leu Gln Ile Ser Met Cys Gln Lys Lys Ala Lys Glu 
385                 390                 395                 400 


His Asn Glu Arg Asp Arg Arg Ile Tyr Ala Asn Met Phe Lys Lys Phe 
                405                 410                 415     


Ala Glu Gln Asp Ala Lys Glu Glu Ala Asn Lys Ala Met Gly Lys Lys 
            420                 425                 430         


Thr Ser Glu Gly Val Thr Asn Glu Lys Gly Thr Asp Ser Gln Ala Met 
        435                 440                 445             


Glu Glu Glu Lys Pro Glu Gly His Val 
    450                 455         


<210>  3394
<211>  307
<212>  PRT
<213>  homo sapiens

<400>  3394

Met Pro Arg Ser Phe Leu Val Lys Lys Ile Lys Gly Asp Gly Phe Gln 
1               5                   10                  15      


Cys Ser Gly Val Pro Ala Pro Thr Tyr His Pro Leu Glu Thr Ala Tyr 
            20                  25                  30          


Val Leu Pro Gly Ala Arg Gly Pro Pro Gly Asp Asn Gly Tyr Ala Pro 
        35                  40                  45              


His Arg Leu Pro Pro Ser Ser Tyr Asp Ala Asp Gln Lys Pro Gly Leu 
    50                  55                  60                  


Glu Leu Ala Pro Ala Glu Pro Ala Tyr Pro Pro Ala Ala Pro Glu Glu 
65                  70                  75                  80  


Tyr Ser Asp Pro Glu Ser Pro Gln Ser Ser Leu Ser Ala Arg Tyr Phe 
                85                  90                  95      


Arg Gly Glu Ala Ala Val Thr Asp Ser Tyr Ser Met Asp Ala Phe Phe 
            100                 105                 110         


Ile Ser Asp Gly Arg Ser Arg Arg Arg Arg Gly Gly Gly Gly Gly Asp 
        115                 120                 125             


Ala Gly Gly Ser Gly Asp Ala Gly Gly Ala Gly Gly Arg Ala Gly Arg 
    130                 135                 140                 


Ala Gly Ala Gln Ala Gly Gly Gly His Arg His Ala Cys Ala Glu Cys 
145                 150                 155                 160 


Gly Lys Thr Tyr Ala Thr Ser Ser Asn Leu Ser Arg His Lys Gln Thr 
                165                 170                 175     


His Arg Ser Leu Asp Ser Gln Leu Ala Arg Lys Cys Pro Thr Cys Gly 
            180                 185                 190         


Lys Ala Tyr Val Ser Met Pro Ala Leu Ala Met His Leu Leu Thr His 
        195                 200                 205             


Asn Leu Arg His Lys Cys Gly Val Cys Gly Lys Ala Phe Ser Arg Pro 
    210                 215                 220                 


Trp Leu Leu Gln Gly His Met Arg Ser His Thr Gly Glu Lys Pro Phe 
225                 230                 235                 240 


Gly Cys Ala His Cys Gly Lys Ala Phe Ala Asp Arg Ser Asn Leu Arg 
                245                 250                 255     


Ala His Met Gln Thr His Ser Ala Phe Lys His Tyr Arg Cys Arg Gln 
            260                 265                 270         


Cys Asp Lys Ser Phe Ala Leu Lys Ser Tyr Leu His Lys His Cys Glu 
        275                 280                 285             


Ala Ala Cys Ala Lys Ala Ala Glu Pro Pro Pro Pro Thr Pro Ala Gly 
    290                 295                 300                 


Pro Ala Ser 
305         


<210>  3395
<211>  270
<212>  PRT
<213>  homo sapiens

<400>  3395

Met Ala Ala Ser Ser Ser Gly Glu Lys Glu Lys Glu Arg Leu Gly Gly 
1               5                   10                  15      


Gly Leu Gly Val Ala Gly Gly Asn Ser Thr Arg Glu Arg Leu Leu Ser 
            20                  25                  30          


Ala Leu Glu Asp Leu Glu Val Leu Ser Arg Glu Leu Ile Glu Met Leu 
        35                  40                  45              


Ala Ile Ser Arg Asn Gln Lys Leu Leu Gln Ala Gly Glu Glu Asn Gln 
    50                  55                  60                  


Val Leu Glu Leu Leu Ile His Arg Asp Gly Glu Phe Gln Glu Leu Met 
65                  70                  75                  80  


Lys Leu Ala Leu Asn Gln Gly Lys Ile His His Glu Met Gln Val Leu 
                85                  90                  95      


Glu Lys Glu Val Glu Lys Arg Asp Ser Asp Ile Gln Gln Leu Gln Lys 
            100                 105                 110         


Gln Leu Lys Glu Ala Glu Gln Ile Leu Ala Thr Ala Val Tyr Gln Ala 
        115                 120                 125             


Lys Glu Lys Leu Lys Ser Ile Glu Lys Ala Arg Lys Gly Ala Ile Ser 
    130                 135                 140                 


Ser Glu Glu Ile Ile Lys Tyr Ala His Arg Ile Ser Ala Ser Asn Ala 
145                 150                 155                 160 


Val Cys Ala Pro Leu Thr Trp Val Pro Gly Asp Pro Arg Arg Pro Tyr 
                165                 170                 175     


Pro Thr Asp Leu Glu Met Arg Ser Gly Leu Leu Gly Gln Met Asn Asn 
            180                 185                 190         


Pro Ser Thr Asn Gly Val Asn Gly His Leu Pro Gly Asp Ala Leu Ala 
        195                 200                 205             


Ala Gly Arg Leu Pro Asp Val Leu Ala Pro Gln Tyr Pro Trp Gln Ser 
    210                 215                 220                 


Asn Asp Met Ser Met Asn Met Leu Pro Pro Asn His Ser Ser Asp Phe 
225                 230                 235                 240 


Leu Leu Glu Pro Pro Gly His Asn Lys Glu Asn Glu Asp Asp Val Glu 
                245                 250                 255     


Ile Met Ser Thr Asp Ser Ser Ser Ser Ser Ser Glu Ser Asp 
            260                 265                 270 


<210>  3396
<211>  432
<212>  PRT
<213>  homo sapiens

<400>  3396

Met Leu Gly Asn Ser Ala Pro Gly Pro Ala Thr Arg Glu Ala Gly Ser 
1               5                   10                  15      


Ala Leu Leu Ala Leu Gln Gln Thr Ala Leu Gln Glu Asp Gln Glu Asn 
            20                  25                  30          


Ile Asn Pro Glu Lys Ala Ala Pro Val Gln Gln Pro Arg Thr Arg Ala 
        35                  40                  45              


Ala Leu Ala Val Leu Lys Ser Gly Asn Pro Arg Gly Leu Ala Gln Gln 
    50                  55                  60                  


Gln Arg Pro Lys Thr Arg Arg Val Ala Pro Leu Lys Asp Leu Pro Val 
65                  70                  75                  80  


Asn Asp Glu His Val Thr Val Pro Pro Trp Lys Ala Asn Ser Lys Gln 
                85                  90                  95      


Pro Ala Phe Thr Ile His Val Asp Glu Ala Glu Lys Glu Ala Gln Lys 
            100                 105                 110         


Lys Pro Ala Glu Ser Gln Lys Ile Glu Arg Glu Asp Ala Leu Ala Phe 
        115                 120                 125             


Asn Ser Ala Ile Ser Leu Pro Gly Pro Arg Lys Pro Leu Val Pro Leu 
    130                 135                 140                 


Asp Tyr Pro Met Asp Gly Ser Phe Glu Ser Pro His Thr Met Asp Met 
145                 150                 155                 160 


Ser Ile Val Leu Glu Asp Glu Lys Pro Val Ser Val Asn Glu Val Pro 
                165                 170                 175     


Asp Tyr His Glu Asp Ile His Thr Tyr Leu Arg Glu Met Glu Val Lys 
            180                 185                 190         


Cys Lys Pro Lys Val Gly Tyr Met Lys Lys Gln Pro Asp Ile Thr Asn 
        195                 200                 205             


Ser Met Arg Ala Ile Leu Val Asp Trp Leu Val Glu Val Gly Glu Glu 
    210                 215                 220                 


Tyr Lys Leu Gln Asn Glu Thr Leu His Leu Ala Val Asn Tyr Ile Asp 
225                 230                 235                 240 


Arg Phe Leu Ser Ser Met Ser Val Leu Arg Gly Lys Leu Gln Leu Val 
                245                 250                 255     


Gly Thr Ala Ala Met Leu Leu Ala Ser Lys Phe Glu Glu Ile Tyr Pro 
            260                 265                 270         


Pro Glu Val Ala Glu Phe Val Tyr Ile Thr Asp Asp Thr Tyr Thr Lys 
        275                 280                 285             


Lys Gln Val Leu Arg Met Glu His Leu Val Leu Lys Val Leu Thr Phe 
    290                 295                 300                 


Asp Leu Ala Ala Pro Thr Val Asn Gln Phe Leu Thr Gln Tyr Phe Leu 
305                 310                 315                 320 


His Gln Gln Pro Ala Asn Cys Lys Val Glu Ser Leu Ala Met Phe Leu 
                325                 330                 335     


Gly Glu Leu Ser Leu Ile Asp Ala Asp Pro Tyr Leu Lys Tyr Leu Pro 
            340                 345                 350         


Ser Val Ile Ala Gly Ala Ala Phe His Leu Ala Leu Tyr Thr Val Thr 
        355                 360                 365             


Gly Gln Ser Trp Pro Glu Ser Leu Ile Arg Lys Thr Gly Tyr Thr Leu 
    370                 375                 380                 


Glu Ser Leu Lys Pro Cys Leu Met Asp Leu His Gln Thr Tyr Leu Lys 
385                 390                 395                 400 


Ala Pro Gln His Ala Gln Gln Ser Ile Arg Glu Lys Tyr Lys Asn Ser 
                405                 410                 415     


Lys Tyr His Gly Val Ser Leu Leu Asn Pro Pro Glu Thr Leu Asn Leu 
            420                 425                 430         


<210>  3397
<211>  777
<212>  PRT
<213>  homo sapiens

<400>  3397

Met Asp Ser Lys Glu Ser Leu Thr Pro Gly Arg Glu Glu Asn Pro Ser 
1               5                   10                  15      


Ser Val Leu Ala Gln Glu Arg Gly Asp Val Met Asp Phe Tyr Lys Thr 
            20                  25                  30          


Leu Arg Gly Gly Ala Thr Val Lys Val Ser Ala Ser Ser Pro Ser Leu 
        35                  40                  45              


Ala Val Ala Ser Gln Ser Asp Ser Lys Gln Arg Arg Leu Leu Val Asp 
    50                  55                  60                  


Phe Pro Lys Gly Ser Val Ser Asn Ala Gln Gln Pro Asp Leu Ser Lys 
65                  70                  75                  80  


Ala Val Ser Leu Ser Met Gly Leu Tyr Met Gly Glu Thr Glu Thr Lys 
                85                  90                  95      


Val Met Gly Asn Asp Leu Gly Phe Pro Gln Gln Gly Gln Ile Ser Leu 
            100                 105                 110         


Ser Ser Gly Glu Thr Asp Leu Lys Leu Leu Glu Glu Ser Ile Ala Asn 
        115                 120                 125             


Leu Asn Arg Ser Thr Ser Val Pro Glu Asn Pro Lys Ser Ser Ala Ser 
    130                 135                 140                 


Thr Ala Val Ser Ala Ala Pro Thr Glu Lys Glu Phe Pro Lys Thr His 
145                 150                 155                 160 


Ser Asp Val Ser Ser Glu Gln Gln His Leu Lys Gly Gln Thr Gly Thr 
                165                 170                 175     


Asn Gly Gly Asn Val Lys Leu Tyr Thr Thr Asp Gln Ser Thr Phe Asp 
            180                 185                 190         


Ile Leu Gln Asp Leu Glu Phe Ser Ser Gly Ser Pro Gly Lys Glu Thr 
        195                 200                 205             


Asn Glu Ser Pro Trp Arg Ser Asp Leu Leu Ile Asp Glu Asn Cys Leu 
    210                 215                 220                 


Leu Ser Pro Leu Ala Gly Glu Asp Asp Ser Phe Leu Leu Glu Gly Asn 
225                 230                 235                 240 


Ser Asn Glu Asp Cys Lys Pro Leu Ile Leu Pro Asp Thr Lys Pro Lys 
                245                 250                 255     


Ile Lys Asp Asn Gly Asp Leu Val Leu Ser Ser Pro Ser Asn Val Thr 
            260                 265                 270         


Leu Pro Gln Val Lys Thr Glu Lys Glu Asp Phe Ile Glu Leu Cys Thr 
        275                 280                 285             


Pro Gly Val Ile Lys Gln Glu Lys Leu Gly Thr Val Tyr Cys Gln Ala 
    290                 295                 300                 


Ser Phe Pro Gly Ala Asn Ile Ile Gly Asn Lys Met Ser Ala Ile Ser 
305                 310                 315                 320 


Val His Gly Val Ser Thr Ser Gly Gly Gln Met Tyr His Tyr Asp Met 
                325                 330                 335     


Asn Thr Ala Ser Leu Ser Gln Gln Gln Asp Gln Lys Pro Ile Phe Asn 
            340                 345                 350         


Val Ile Pro Pro Ile Pro Val Gly Ser Glu Asn Trp Asn Arg Cys Gln 
        355                 360                 365             


Gly Ser Gly Asp Asp Asn Leu Thr Ser Leu Gly Thr Leu Asn Phe Pro 
    370                 375                 380                 


Gly Arg Thr Val Phe Ser Asn Gly Tyr Ser Ser Pro Ser Met Arg Pro 
385                 390                 395                 400 


Asp Val Ser Ser Pro Pro Ser Ser Ser Ser Thr Ala Thr Thr Gly Pro 
                405                 410                 415     


Pro Pro Lys Leu Cys Leu Val Cys Ser Asp Glu Ala Ser Gly Cys His 
            420                 425                 430         


Tyr Gly Val Leu Thr Cys Gly Ser Cys Lys Val Phe Phe Lys Arg Ala 
        435                 440                 445             


Val Glu Gly Gln His Asn Tyr Leu Cys Ala Gly Arg Asn Asp Cys Ile 
    450                 455                 460                 


Ile Asp Lys Ile Arg Arg Lys Asn Cys Pro Ala Cys Arg Tyr Arg Lys 
465                 470                 475                 480 


Cys Leu Gln Ala Gly Met Asn Leu Glu Ala Arg Lys Thr Lys Lys Lys 
                485                 490                 495     


Ile Lys Gly Ile Gln Gln Ala Thr Thr Gly Val Ser Gln Glu Thr Ser 
            500                 505                 510         


Glu Asn Pro Gly Asn Lys Thr Ile Val Pro Ala Thr Leu Pro Gln Leu 
        515                 520                 525             


Thr Pro Thr Leu Val Ser Leu Leu Glu Val Ile Glu Pro Glu Val Leu 
    530                 535                 540                 


Tyr Ala Gly Tyr Asp Ser Ser Val Pro Asp Ser Thr Trp Arg Ile Met 
545                 550                 555                 560 


Thr Thr Leu Asn Met Leu Gly Gly Arg Gln Val Ile Ala Ala Val Lys 
                565                 570                 575     


Trp Ala Lys Ala Ile Pro Gly Phe Arg Asn Leu His Leu Asp Asp Gln 
            580                 585                 590         


Met Thr Leu Leu Gln Tyr Ser Trp Met Phe Leu Met Ala Phe Ala Leu 
        595                 600                 605             


Gly Trp Arg Ser Tyr Arg Gln Ser Ser Ala Asn Leu Leu Cys Phe Ala 
    610                 615                 620                 


Pro Asp Leu Ile Ile Asn Glu Gln Arg Met Thr Leu Pro Cys Met Tyr 
625                 630                 635                 640 


Asp Gln Cys Lys His Met Leu Tyr Val Ser Ser Glu Leu His Arg Leu 
                645                 650                 655     


Gln Val Ser Tyr Glu Glu Tyr Leu Cys Met Lys Thr Leu Leu Leu Leu 
            660                 665                 670         


Ser Ser Val Pro Lys Asp Gly Leu Lys Ser Gln Glu Leu Phe Asp Glu 
        675                 680                 685             


Ile Arg Met Thr Tyr Ile Lys Glu Leu Gly Lys Ala Ile Val Lys Arg 
    690                 695                 700                 


Glu Gly Asn Ser Ser Gln Asn Trp Gln Arg Phe Tyr Gln Leu Thr Lys 
705                 710                 715                 720 


Leu Leu Asp Ser Met His Glu Val Val Glu Asn Leu Leu Asn Tyr Cys 
                725                 730                 735     


Phe Gln Thr Phe Leu Asp Lys Thr Met Ser Ile Glu Phe Pro Glu Met 
            740                 745                 750         


Leu Ala Glu Ile Ile Thr Asn Gln Ile Pro Lys Tyr Ser Asn Gly Asn 
        755                 760                 765             


Ile Lys Lys Leu Leu Phe His Gln Lys 
    770                 775         


<210>  3398
<211>  720
<212>  PRT
<213>  homo sapiens

<400>  3398

Met Ser Val Ser Gly Lys Lys Glu Phe Asp Val Lys Gln Ile Leu Arg 
1               5                   10                  15      


Leu Arg Trp Arg Trp Phe Ser His Pro Phe Gln Gly Ser Thr Asn Thr 
            20                  25                  30          


Gly Ser Cys Leu Gln Gln Glu Gly Tyr Glu His Arg Gly Thr Pro Val 
        35                  40                  45              


Gln Gly Arg Leu Lys Ser His Ser Arg Asp Arg Asn Gly Leu Lys Lys 
    50                  55                  60                  


Ser Asn Ser Pro Val His His Asn Ile Leu Ala Pro Val Pro Gly Pro 
65                  70                  75                  80  


Ala Pro Ala His Gln Arg Ala Val Gln Asn Leu Gln Gln His Asn Leu 
                85                  90                  95      


Ile Val His Phe Gln Ala Asn Glu Asp Thr Pro Lys Ser Val Pro Glu 
            100                 105                 110         


Lys Asn Leu Phe Lys Glu Ala Cys Glu Lys Arg Ala Gln Asp Leu Glu 
        115                 120                 125             


Met Met Ala Asp Asp Asn Ile Glu Asp Ser Thr Ala Arg Leu Asp Thr 
    130                 135                 140                 


Gln His Ser Glu Asp Met Asn Ala Thr Arg Ser Glu Glu Gln Phe His 
145                 150                 155                 160 


Val Ile Asn His Ala Glu Gln Thr Leu Arg Lys Met Glu Asn Tyr Leu 
                165                 170                 175     


Lys Glu Lys Gln Leu Cys Asp Val Leu Leu Ile Ala Gly His Leu Arg 
            180                 185                 190         


Ile Pro Ala His Arg Leu Val Leu Ser Ala Val Ser Asp Tyr Phe Ala 
        195                 200                 205             


Ala Met Phe Thr Asn Asp Val Leu Glu Ala Lys Gln Glu Glu Val Arg 
    210                 215                 220                 


Met Glu Gly Val Asp Pro Asn Ala Leu Asn Ser Leu Val Gln Tyr Ala 
225                 230                 235                 240 


Tyr Thr Gly Val Leu Gln Leu Lys Glu Asp Thr Ile Glu Ser Leu Leu 
                245                 250                 255     


Ala Ala Ala Cys Leu Leu Gln Leu Thr Gln Val Ile Asp Val Cys Ser 
            260                 265                 270         


Asn Phe Leu Ile Lys Gln Leu His Pro Ser Asn Cys Leu Gly Ile Arg 
        275                 280                 285             


Ser Phe Gly Asp Ala Gln Gly Cys Thr Glu Leu Leu Asn Val Ala His 
    290                 295                 300                 


Lys Tyr Thr Met Glu His Phe Ile Glu Val Ile Lys Asn Gln Glu Phe 
305                 310                 315                 320 


Leu Leu Leu Pro Ala Asn Glu Ile Ser Lys Leu Leu Cys Ser Asp Asp 
                325                 330                 335     


Ile Asn Val Pro Asp Glu Glu Thr Ile Phe His Ala Leu Met Gln Trp 
            340                 345                 350         


Val Gly His Asp Val Gln Asn Arg Gln Gly Glu Leu Gly Met Leu Leu 
        355                 360                 365             


Ser Tyr Ile Arg Leu Pro Leu Leu Pro Pro Gln Leu Leu Ala Asp Leu 
    370                 375                 380                 


Glu Thr Ser Ser Met Phe Thr Gly Asp Leu Glu Cys Gln Lys Leu Leu 
385                 390                 395                 400 


Met Glu Ala Met Lys Tyr His Leu Leu Pro Glu Arg Arg Ser Met Met 
                405                 410                 415     


Gln Ser Pro Arg Thr Lys Pro Arg Lys Ser Thr Val Gly Ala Leu Tyr 
            420                 425                 430         


Ala Val Gly Gly Met Asp Ala Met Lys Gly Thr Thr Thr Ile Glu Lys 
        435                 440                 445             


Tyr Asp Leu Arg Thr Asn Ser Trp Leu His Ile Gly Thr Met Asn Gly 
    450                 455                 460                 


Arg Arg Leu Gln Phe Gly Val Ala Val Ile Asp Asn Lys Leu Tyr Val 
465                 470                 475                 480 


Val Gly Gly Arg Asp Gly Leu Lys Thr Leu Asn Thr Val Glu Cys Phe 
                485                 490                 495     


Asn Pro Val Gly Lys Ile Trp Thr Val Met Pro Pro Met Ser Thr His 
            500                 505                 510         


Arg His Gly Leu Gly Val Ala Thr Leu Glu Gly Pro Met Tyr Ala Val 
        515                 520                 525             


Gly Gly His Asp Gly Trp Ser Tyr Leu Asn Thr Val Glu Arg Trp Asp 
    530                 535                 540                 


Pro Glu Gly Arg Gln Trp Asn Tyr Val Ala Ser Met Ser Thr Pro Arg 
545                 550                 555                 560 


Ser Thr Val Gly Val Val Ala Leu Asn Asn Lys Leu Tyr Ala Ile Gly 
                565                 570                 575     


Gly Arg Asp Gly Ser Ser Cys Leu Lys Ser Met Glu Tyr Phe Asp Pro 
            580                 585                 590         


His Thr Asn Lys Trp Ser Leu Cys Ala Pro Met Ser Lys Arg Arg Gly 
        595                 600                 605             


Gly Val Gly Val Ala Thr Tyr Asn Gly Phe Leu Tyr Val Val Gly Gly 
    610                 615                 620                 


His Asp Ala Pro Ala Ser Asn His Cys Ser Arg Leu Ser Asp Cys Val 
625                 630                 635                 640 


Glu Arg Tyr Asp Pro Lys Gly Asp Ser Trp Ser Thr Val Ala Pro Leu 
                645                 650                 655     


Ser Val Pro Arg Asp Ala Val Ala Val Cys Pro Leu Gly Asp Lys Leu 
            660                 665                 670         


Tyr Val Val Gly Gly Tyr Asp Gly His Thr Tyr Leu Asn Thr Val Glu 
        675                 680                 685             


Ser Tyr Asp Ala Gln Arg Asn Glu Trp Lys Glu Ser Met Gln Glu Leu 
    690                 695                 700                 


Leu Gln Asn Phe Tyr Thr Thr Gln Lys Leu Lys Glu Thr Leu Gly His 
705                 710                 715                 720 


<210>  3399
<211>  548
<212>  PRT
<213>  homo sapiens

<400>  3399

Met Asn Glu Gly Ala Pro Gly Asp Ser Asp Leu Glu Thr Glu Ala Arg 
1               5                   10                  15      


Val Pro Trp Ser Ile Met Gly His Cys Leu Arg Thr Gly Gln Ala Arg 
            20                  25                  30          


Met Ser Ala Thr Pro Thr Pro Ala Gly Glu Gly Ala Arg Ser Ser Ser 
        35                  40                  45              


Thr Cys Ser Ser Leu Ser Arg Leu Phe Trp Ser Gln Leu Glu His Ile 
    50                  55                  60                  


Asn Trp Asp Gly Ala Thr Ala Lys Asn Phe Ile Asn Leu Arg Glu Phe 
65                  70                  75                  80  


Phe Ser Phe Leu Leu Pro Ala Leu Arg Lys Ala Gln Ile Glu Ile Ile 
                85                  90                  95      


Pro Cys Lys Ile Cys Gly Asp Lys Ser Ser Gly Ile His Tyr Gly Val 
            100                 105                 110         


Ile Thr Cys Glu Gly Cys Lys Gly Phe Phe Arg Arg Ser Gln Gln Ser 
        115                 120                 125             


Asn Ala Thr Tyr Ser Cys Pro Arg Gln Lys Asn Cys Leu Ile Asp Arg 
    130                 135                 140                 


Thr Ser Arg Asn Arg Cys Gln His Cys Arg Leu Gln Lys Cys Leu Ala 
145                 150                 155                 160 


Val Gly Met Ser Arg Asp Ala Val Lys Phe Gly Arg Met Ser Lys Lys 
                165                 170                 175     


Gln Arg Asp Ser Leu Tyr Ala Glu Val Gln Lys His Arg Met Gln Gln 
            180                 185                 190         


Gln Gln Arg Asp His Gln Gln Gln Pro Gly Glu Ala Glu Pro Leu Thr 
        195                 200                 205             


Pro Thr Tyr Asn Ile Ser Ala Asn Gly Leu Thr Glu Leu His Asp Asp 
    210                 215                 220                 


Leu Ser Asn Tyr Ile Asp Gly His Thr Pro Glu Gly Ser Lys Ala Asp 
225                 230                 235                 240 


Ser Ala Val Ser Ser Phe Tyr Leu Asp Ile Gln Pro Ser Pro Asp Gln 
                245                 250                 255     


Ser Gly Leu Asp Ile Asn Gly Ile Lys Pro Glu Pro Ile Cys Asp Tyr 
            260                 265                 270         


Thr Pro Ala Ser Gly Phe Phe Pro Tyr Cys Ser Phe Thr Asn Gly Glu 
        275                 280                 285             


Thr Ser Pro Thr Val Ser Met Ala Glu Leu Glu His Leu Ala Gln Asn 
    290                 295                 300                 


Ile Ser Lys Ser His Leu Glu Thr Cys Gln Tyr Leu Arg Glu Glu Leu 
305                 310                 315                 320 


Gln Gln Ile Thr Trp Gln Thr Phe Leu Gln Glu Glu Ile Glu Asn Tyr 
                325                 330                 335     


Gln Asn Lys Gln Arg Glu Val Met Trp Gln Leu Cys Ala Ile Lys Ile 
            340                 345                 350         


Thr Glu Ala Ile Gln Tyr Val Val Glu Phe Ala Lys Arg Ile Asp Gly 
        355                 360                 365             


Phe Met Glu Leu Cys Gln Asn Asp Gln Ile Val Leu Leu Lys Ala Gly 
    370                 375                 380                 


Ser Leu Glu Val Val Phe Ile Arg Met Cys Arg Ala Phe Asp Ser Gln 
385                 390                 395                 400 


Asn Asn Thr Val Tyr Phe Asp Gly Lys Tyr Ala Ser Pro Asp Val Phe 
                405                 410                 415     


Lys Ser Leu Gly Cys Glu Asp Phe Ile Ser Phe Val Phe Glu Phe Gly 
            420                 425                 430         


Lys Ser Leu Cys Ser Met His Leu Thr Glu Asp Glu Ile Ala Leu Phe 
        435                 440                 445             


Ser Ala Phe Val Leu Met Ser Ala Asp Arg Ser Trp Leu Gln Glu Lys 
    450                 455                 460                 


Val Lys Ile Glu Lys Leu Gln Gln Lys Ile Gln Leu Ala Leu Gln His 
465                 470                 475                 480 


Val Leu Gln Lys Asn His Arg Glu Asp Gly Ile Leu Thr Lys Leu Ile 
                485                 490                 495     


Cys Lys Val Ser Thr Leu Arg Ala Leu Cys Gly Arg His Thr Glu Lys 
            500                 505                 510         


Leu Met Ala Phe Lys Ala Ile Tyr Pro Asp Ile Val Arg Leu His Phe 
        515                 520                 525             


Pro Pro Leu Tyr Lys Glu Leu Phe Thr Ser Glu Phe Glu Pro Ala Met 
    530                 535                 540                 


Gln Ile Asp Gly 
545             


<210>  3400
<211>  501
<212>  PRT
<213>  homo sapiens

<400>  3400

Met Ser Glu Thr Glu Phe His His Gly Ala Gln Ala Gly Leu Glu Leu 
1               5                   10                  15      


Leu Arg Ser Ser Asn Ser Pro Thr Ser Ala Ser Gln Ser Ala Gly Met 
            20                  25                  30          


Thr Val Thr Asp Gln Ala Phe Val Thr Leu Ala Thr Asn Asp Ile Tyr 
        35                  40                  45              


Cys Gln Gly Ala Leu Val Leu Gly Gln Ser Leu Arg Arg His Arg Leu 
    50                  55                  60                  


Thr Arg Lys Leu Val Val Leu Ile Thr Pro Gln Val Ser Ser Leu Leu 
65                  70                  75                  80  


Arg Val Ile Leu Ser Lys Val Phe Asp Glu Val Ile Glu Val Asn Leu 
                85                  90                  95      


Ile Asp Ser Ala Asp Tyr Ile His Leu Ala Phe Leu Lys Arg Pro Glu 
            100                 105                 110         


Leu Gly Leu Thr Leu Thr Lys Leu His Cys Trp Thr Leu Thr His Tyr 
        115                 120                 125             


Ser Lys Cys Val Phe Leu Asp Ala Asp Thr Leu Val Leu Ser Asn Val 
    130                 135                 140                 


Asp Glu Leu Phe Asp Arg Gly Glu Phe Ser Ala Ala Pro Asp Pro Gly 
145                 150                 155                 160 


Trp Pro Asp Cys Phe Asn Ser Gly Val Phe Val Phe Gln Pro Ser Leu 
                165                 170                 175     


His Thr His Lys Leu Leu Leu Gln His Ala Met Glu His Gly Ser Phe 
            180                 185                 190         


Asp Gly Ala Asp Gln Gly Leu Leu Asn Ser Phe Phe Arg Asn Trp Ser 
        195                 200                 205             


Thr Thr Asp Ile His Lys His Leu Pro Phe Ile Tyr Asn Leu Ser Ser 
    210                 215                 220                 


Asn Thr Met Tyr Thr Tyr Ser Pro Ala Phe Lys Gln Phe Gly Ser Ser 
225                 230                 235                 240 


Ala Lys Val Val His Phe Leu Gly Ser Met Lys Pro Trp Asn Tyr Lys 
                245                 250                 255     


Tyr Asn Pro Gln Ser Gly Ser Val Leu Glu Gln Gly Ser Ala Ser Ser 
            260                 265                 270         


Ser Gln His Gln Ala Ala Phe Leu His Leu Trp Trp Thr Val Tyr Gln 
        275                 280                 285             


Asn Asn Val Leu Pro Leu Tyr Lys Ser Val Gln Ala Gly Glu Ala Arg 
    290                 295                 300                 


Ala Ser Pro Gly His Thr Leu Cys His Ser Asp Val Gly Gly Pro Cys 
305                 310                 315                 320 


Ala Asp Ser Ala Ser Gly Val Gly Glu Pro Cys Glu Asn Ser Thr Pro 
                325                 330                 335     


Ser Ala Gly Val Pro Cys Ala Asn Ser Pro Leu Gly Ser Asn Gln Pro 
            340                 345                 350         


Ala Gln Gly Leu Pro Glu Pro Thr Gln Ile Val Asp Glu Thr Leu Ser 
        355                 360                 365             


Leu Pro Glu Gly Arg Arg Ser Glu Asp Met Ile Ala Cys Pro Glu Thr 
    370                 375                 380                 


Glu Thr Pro Ala Val Ile Thr Cys Asp Pro Leu Ser Gln Pro Ser Pro 
385                 390                 395                 400 


Gln Pro Ala Asp Phe Thr Glu Thr Glu Thr Ile Leu Gln Pro Ala Asn 
                405                 410                 415     


Lys Val Glu Ser Val Ser Ser Glu Glu Thr Phe Glu Pro Ser Gln Glu 
            420                 425                 430         


Leu Pro Ala Glu Ala Leu Arg Asp Pro Ser Leu Gln Asp Ala Leu Glu 
        435                 440                 445             


Val Asp Leu Ala Val Ser Val Ser Gln Ile Ser Ile Glu Glu Lys Val 
    450                 455                 460                 


Lys Glu Leu Ser Pro Glu Glu Glu Arg Arg Lys Trp Glu Glu Gly Arg 
465                 470                 475                 480 


Ile Asp Tyr Met Gly Lys Asp Ala Phe Ala Arg Ile Gln Glu Lys Leu 
                485                 490                 495     


Asp Arg Phe Leu Gln 
            500     


<210>  3401
<211>  325
<212>  PRT
<213>  homo sapiens

<400>  3401

Met Ala Asn Ala Leu Ala Ser Ala Thr Cys Glu Arg Cys Lys Gly Gly 
1               5                   10                  15      


Phe Ala Pro Ala Glu Lys Ile Val Asn Ser Asn Gly Glu Leu Tyr His 
            20                  25                  30          


Glu Gln Cys Phe Val Cys Ala Gln Cys Phe Gln Gln Phe Pro Glu Gly 
        35                  40                  45              


Leu Phe Tyr Glu Phe Glu Gly Arg Lys Tyr Cys Glu His Asp Phe Gln 
    50                  55                  60                  


Met Leu Phe Ala Pro Cys Cys His Gln Cys Gly Glu Phe Ile Ile Gly 
65                  70                  75                  80  


Arg Val Ile Lys Ala Met Asn Asn Ser Trp His Pro Glu Cys Phe Arg 
                85                  90                  95      


Cys Asp Leu Cys Gln Glu Val Leu Ala Asp Ile Gly Phe Val Lys Asn 
            100                 105                 110         


Ala Gly Arg His Leu Cys Arg Pro Cys His Asn Arg Glu Lys Ala Arg 
        115                 120                 125             


Gly Leu Gly Lys Tyr Ile Cys Gln Lys Cys His Ala Ile Ile Asp Glu 
    130                 135                 140                 


Gln Pro Leu Ile Phe Lys Asn Asp Pro Tyr His Pro Asp His Phe Asn 
145                 150                 155                 160 


Cys Ala Asn Cys Gly Lys Glu Leu Thr Ala Asp Ala Arg Glu Leu Lys 
                165                 170                 175     


Gly Glu Leu Tyr Cys Leu Pro Cys His Asp Lys Met Gly Val Pro Ile 
            180                 185                 190         


Cys Gly Ala Cys Arg Arg Pro Ile Glu Gly Arg Val Val Asn Ala Met 
        195                 200                 205             


Gly Lys Gln Trp His Val Glu His Phe Val Cys Ala Lys Cys Glu Lys 
    210                 215                 220                 


Pro Phe Leu Gly His Arg His Tyr Glu Arg Lys Gly Leu Ala Tyr Cys 
225                 230                 235                 240 


Glu Thr His Tyr Asn Gln Leu Phe Gly Asp Val Cys Phe His Cys Asn 
                245                 250                 255     


Arg Val Ile Glu Gly Asp Val Val Ser Ala Leu Asn Lys Ala Trp Cys 
            260                 265                 270         


Val Asn Cys Phe Ala Cys Ser Thr Cys Asn Thr Lys Leu Thr Leu Lys 
        275                 280                 285             


Asn Lys Phe Val Glu Phe Asp Met Lys Pro Val Cys Lys Lys Cys Tyr 
    290                 295                 300                 


Glu Lys Phe Pro Leu Glu Leu Lys Lys Arg Leu Lys Lys Leu Ala Glu 
305                 310                 315                 320 


Thr Leu Gly Arg Lys 
                325 


<210>  3402
<211>  397
<212>  PRT
<213>  homo sapiens

<400>  3402

Met Glu Ile Val Gly Cys Arg Ala Glu Asp Asn Ser Cys Pro Phe Arg 
1               5                   10                  15      


Pro Pro Ala Met Leu Phe His Gly Ile Ser Gly Gly His Ile Gln Gly 
            20                  25                  30          


Ile Met Glu Glu Met Glu Arg Arg Ser Lys Thr Glu Ala Arg Leu Ala 
        35                  40                  45              


Lys Gly Ala Gln Leu Asn Gly Arg Asp Ala Gly Met Pro Pro Leu Ser 
    50                  55                  60                  


Pro Glu Lys Pro Ala Leu Cys Ala Gly Cys Gly Gly Lys Ile Ser Asp 
65                  70                  75                  80  


Arg Tyr Tyr Leu Leu Ala Val Asp Lys Gln Trp His Leu Arg Cys Leu 
                85                  90                  95      


Lys Cys Cys Glu Cys Lys Leu Ala Leu Glu Ser Glu Leu Thr Cys Phe 
            100                 105                 110         


Ala Lys Asp Gly Ser Ile Tyr Cys Lys Glu Asp Tyr Tyr Arg Arg Phe 
        115                 120                 125             


Ser Val Gln Arg Cys Ala Arg Cys His Leu Gly Ile Ser Ala Ser Glu 
    130                 135                 140                 


Met Val Met Arg Ala Arg Asp Ser Val Tyr His Leu Ser Cys Phe Thr 
145                 150                 155                 160 


Cys Ser Thr Cys Asn Lys Thr Leu Thr Thr Gly Asp His Phe Gly Met 
                165                 170                 175     


Lys Asp Ser Leu Val Tyr Cys Arg Ala His Phe Glu Thr Leu Leu Gln 
            180                 185                 190         


Gly Glu Tyr Pro Pro Gln Leu Ser Tyr Thr Glu Leu Ala Ala Lys Ser 
        195                 200                 205             


Gly Gly Leu Ala Leu Pro Tyr Phe Asn Gly Thr Gly Thr Val Gln Lys 
    210                 215                 220                 


Gly Arg Pro Arg Lys Arg Lys Ser Pro Ala Leu Gly Val Asp Ile Val 
225                 230                 235                 240 


Asn Tyr Asn Ser Gly Cys Asn Glu Asn Glu Ala Asp His Leu Asp Arg 
                245                 250                 255     


Asp Gln Gln Pro Tyr Pro Pro Ser Gln Lys Thr Lys Arg Met Arg Thr 
            260                 265                 270         


Ser Phe Lys His His Gln Leu Arg Thr Met Lys Ser Tyr Phe Ala Ile 
        275                 280                 285             


Asn His Asn Pro Asp Ala Lys Asp Leu Lys Gln Leu Ala Gln Lys Thr 
    290                 295                 300                 


Gly Leu Thr Lys Arg Val Leu Gln Val Trp Phe Gln Asn Ala Arg Ala 
305                 310                 315                 320 


Lys Phe Arg Arg Asn Leu Leu Arg Gln Glu Asn Gly Gly Val Asp Lys 
                325                 330                 335     


Ala Asp Gly Thr Ser Leu Pro Ala Pro Pro Ser Ala Asp Ser Gly Ala 
            340                 345                 350         


Leu Thr Pro Pro Gly Thr Ala Thr Thr Leu Thr Asp Leu Thr Asn Pro 
        355                 360                 365             


Thr Ile Thr Val Val Thr Ser Val Thr Ser Asn Met Asp Ser His Glu 
    370                 375                 380                 


Ser Gly Ser Pro Ser Gln Thr Thr Leu Thr Asn Leu Phe 
385                 390                 395         


<210>  3403
<211>  150
<212>  PRT
<213>  homo sapiens

<400>  3403

Met Ala Ser Gln Asn Arg Asp Pro Ala Ala Thr Ser Val Ala Ala Ala 
1               5                   10                  15      


Arg Lys Gly Ala Glu Pro Ser Gly Gly Ala Ala Arg Gly Pro Val Gly 
            20                  25                  30          


Lys Arg Leu Gln Gln Glu Leu Met Thr Leu Met Val Tyr Glu Asp Leu 
        35                  40                  45              


Arg Tyr Lys Leu Ser Leu Glu Phe Pro Ser Gly Tyr Pro Tyr Asn Ala 
    50                  55                  60                  


Pro Thr Val Lys Phe Leu Thr Pro Cys Tyr His Pro Asn Val Asp Thr 
65                  70                  75                  80  


Gln Gly Asn Ile Cys Leu Asp Ile Leu Lys Glu Lys Trp Ser Ala Leu 
                85                  90                  95      


Tyr Asp Val Arg Thr Ile Leu Leu Ser Ile Gln Ser Leu Leu Gly Glu 
            100                 105                 110         


Pro Asn Ile Asp Ser Pro Leu Asn Thr His Ala Ala Glu Leu Trp Lys 
        115                 120                 125             


Asn Pro Thr Ala Phe Lys Lys Tyr Leu Gln Glu Thr Tyr Ser Lys Gln 
    130                 135                 140                 


Val Thr Ser Gln Glu Pro 
145                 150 


<210>  3404
<211>  454
<212>  PRT
<213>  homo sapiens

<400>  3404

Met Asp Gly Phe Tyr Asp Gln Gln Val Pro Tyr Met Val Thr Asn Ser 
1               5                   10                  15      


Gln Arg Gly Arg Asn Cys Asn Glu Lys Pro Thr Asn Val Arg Lys Arg 
            20                  25                  30          


Lys Phe Ile Asn Arg Asp Leu Ala His Asp Ser Glu Glu Leu Phe Gln 
        35                  40                  45              


Asp Leu Ser Gln Leu Gln Glu Thr Trp Leu Ala Glu Ala Gln Val Pro 
    50                  55                  60                  


Asp Asn Asp Glu Gln Phe Val Pro Asp Tyr Gln Ala Glu Ser Leu Ala 
65                  70                  75                  80  


Phe His Gly Leu Pro Leu Lys Ile Lys Lys Glu Pro His Ser Pro Cys 
                85                  90                  95      


Ser Glu Ile Ser Ser Ala Cys Ser Gln Glu Gln Pro Phe Lys Phe Ser 
            100                 105                 110         


Tyr Gly Glu Lys Cys Leu Tyr Asn Val Ser Ala Tyr Asp Gln Lys Pro 
        115                 120                 125             


Gln Val Gly Met Arg Pro Ser Asn Pro Pro Thr Pro Ser Ser Thr Pro 
    130                 135                 140                 


Val Ser Pro Leu His His Ala Ser Pro Asn Ser Thr His Thr Pro Lys 
145                 150                 155                 160 


Pro Asp Arg Ala Phe Pro Ala His Leu Pro Pro Ser Gln Ser Ile Pro 
                165                 170                 175     


Asp Ser Ser Tyr Pro Met Asp His Arg Phe Arg Arg Gln Leu Ser Glu 
            180                 185                 190         


Pro Cys Asn Ser Phe Pro Pro Leu Pro Thr Met Pro Arg Glu Gly Arg 
        195                 200                 205             


Pro Met Tyr Gln Arg Gln Met Ser Glu Pro Asn Ile Pro Phe Pro Pro 
    210                 215                 220                 


Gln Gly Phe Lys Gln Glu Tyr His Asp Pro Val Tyr Glu His Asn Thr 
225                 230                 235                 240 


Met Val Gly Ser Ala Ala Ser Gln Ser Phe Pro Pro Pro Leu Met Ile 
                245                 250                 255     


Lys Gln Glu Pro Arg Asp Phe Ala Tyr Asp Ser Gly Cys Met Phe Glu 
            260                 265                 270         


Lys Gly Pro Arg Gln Phe Tyr Asp Asp Thr Cys Val Val Pro Glu Lys 
        275                 280                 285             


Phe Asp Gly Asp Ile Lys Gln Glu Pro Gly Met Tyr Arg Glu Gly Pro 
    290                 295                 300                 


Thr Tyr Gln Arg Arg Gly Ser Leu Gln Leu Trp Gln Phe Leu Val Ala 
305                 310                 315                 320 


Leu Leu Asp Asp Pro Ser Asn Ser His Phe Ile Ala Trp Thr Gly Arg 
                325                 330                 335     


Gly Met Glu Phe Lys Leu Ile Glu Pro Glu Glu Val Ala Arg Arg Trp 
            340                 345                 350         


Gly Ile Gln Lys Asn Arg Pro Ala Met Asn Tyr Asp Lys Leu Ser Arg 
        355                 360                 365             


Ser Leu Arg Tyr Tyr Tyr Glu Lys Gly Ile Met Gln Lys Val Ala Gly 
    370                 375                 380                 


Glu Arg Tyr Val Tyr Lys Phe Val Cys Asp Pro Glu Ala Leu Phe Ser 
385                 390                 395                 400 


Met Ala Phe Pro Asp Asn Gln Arg Pro Leu Leu Lys Thr Asp Met Glu 
                405                 410                 415     


Arg His Ile Asn Glu Glu Asp Thr Val Pro Leu Ser His Phe Asp Glu 
            420                 425                 430         


Ser Met Ala Tyr Met Pro Glu Gly Gly Cys Cys Asn Pro His Pro Tyr 
        435                 440                 445             


Asn Glu Gly Tyr Val Tyr 
    450                 


<210>  3405
<211>  459
<212>  PRT
<213>  homo sapiens

<400>  3405

Met Asp Gly Phe Tyr Asp Gln Gln Val Pro Tyr Met Val Thr Asn Ser 
1               5                   10                  15      


Gln Arg Gly Arg Asn Cys Asn Glu Lys Pro Thr Asn Val Arg Lys Arg 
            20                  25                  30          


Lys Phe Ile Asn Arg Asp Leu Ala His Asp Ser Glu Glu Leu Phe Gln 
        35                  40                  45              


Asp Leu Ser Gln Leu Gln Glu Thr Trp Leu Ala Glu Val Ala Phe His 
    50                  55                  60                  


Gly Leu Pro Leu Lys Ile Lys Lys Glu Pro His Ser Pro Cys Ser Glu 
65                  70                  75                  80  


Ile Ser Ser Ala Cys Ser Gln Glu Gln Pro Phe Lys Phe Ser Tyr Gly 
                85                  90                  95      


Glu Lys Cys Leu Tyr Asn Val Ser Ala Tyr Asp Gln Lys Pro Gln Val 
            100                 105                 110         


Gly Met Arg Pro Ser Asn Pro Pro Thr Pro Ser Ser Thr Pro Val Ser 
        115                 120                 125             


Pro Leu His His Ala Ser Pro Asn Ser Thr His Thr Pro Lys Pro Asp 
    130                 135                 140                 


Arg Ala Phe Pro Ala His Leu Pro Pro Ser Gln Ser Ile Pro Asp Ser 
145                 150                 155                 160 


Ser Tyr Pro Met Asp His Arg Phe Arg Arg Gln Leu Ser Glu Pro Cys 
                165                 170                 175     


Asn Ser Phe Pro Pro Leu Pro Thr Met Pro Arg Glu Gly Arg Pro Met 
            180                 185                 190         


Tyr Gln Arg Gln Met Ser Glu Pro Asn Ile Pro Phe Pro Pro Gln Gly 
        195                 200                 205             


Phe Lys Gln Glu Tyr His Asp Pro Val Tyr Glu His Asn Thr Met Val 
    210                 215                 220                 


Gly Ser Ala Ala Ser Gln Ser Phe Pro Pro Pro Leu Met Ile Lys Gln 
225                 230                 235                 240 


Glu Pro Arg Asp Phe Ala Tyr Asp Ser Glu Val Pro Ser Cys His Ser 
                245                 250                 255     


Ile Tyr Met Arg Gln Glu Gly Phe Leu Ala His Pro Ser Arg Thr Glu 
            260                 265                 270         


Gly Cys Met Phe Glu Lys Gly Pro Arg Gln Phe Tyr Asp Asp Thr Cys 
        275                 280                 285             


Val Val Pro Glu Lys Phe Asp Gly Asp Ile Lys Gln Glu Pro Gly Met 
    290                 295                 300                 


Tyr Arg Glu Gly Pro Thr Tyr Gln Arg Arg Gly Ser Leu Gln Leu Trp 
305                 310                 315                 320 


Gln Phe Leu Val Ala Leu Leu Asp Asp Pro Ser Asn Ser His Phe Ile 
                325                 330                 335     


Ala Trp Thr Gly Arg Gly Met Glu Phe Lys Leu Ile Glu Pro Glu Glu 
            340                 345                 350         


Val Ala Arg Arg Trp Gly Ile Gln Lys Asn Arg Pro Ala Met Asn Tyr 
        355                 360                 365             


Asp Lys Leu Ser Arg Ser Leu Arg Tyr Tyr Tyr Glu Lys Gly Ile Met 
    370                 375                 380                 


Gln Lys Val Ala Gly Glu Arg Tyr Val Tyr Lys Phe Val Cys Asp Pro 
385                 390                 395                 400 


Glu Ala Leu Phe Ser Met Ala Phe Pro Asp Asn Gln Arg Pro Leu Leu 
                405                 410                 415     


Lys Thr Asp Met Glu Arg His Ile Asn Glu Glu Asp Thr Val Pro Leu 
            420                 425                 430         


Ser His Phe Asp Glu Ser Met Ala Tyr Met Pro Glu Gly Gly Cys Cys 
        435                 440                 445             


Asn Pro His Pro Tyr Asn Glu Gly Tyr Val Tyr 
    450                 455                 


<210>  3406
<211>  298
<212>  PRT
<213>  homo sapiens

<400>  3406

Met Thr Ser Leu Thr Gln Arg Ser Ser Gly Leu Val Gln Arg Arg Thr 
1               5                   10                  15      


Glu Ala Ser Arg Asn Ala Ala Asp Lys Glu Arg Ala Ala Gly Gly Gly 
            20                  25                  30          


Ala Gly Ser Ser Glu Asp Asp Ala Gln Ser Arg Arg Asp Glu Gln Asp 
        35                  40                  45              


Asp Asp Asp Lys Gly Asp Ser Lys Glu Thr Arg Leu Thr Leu Met Glu 
    50                  55                  60                  


Glu Val Leu Leu Leu Gly Leu Lys Asp Arg Glu Gly Tyr Thr Ser Phe 
65                  70                  75                  80  


Trp Asn Asp Cys Ile Ser Ser Gly Leu Arg Gly Cys Met Leu Ile Glu 
                85                  90                  95      


Leu Ala Leu Arg Gly Arg Leu Gln Leu Glu Ala Cys Gly Met Arg Arg 
            100                 105                 110         


Lys Ser Leu Leu Thr Arg Lys Val Ile Cys Lys Ser Asp Ala Pro Thr 
        115                 120                 125             


Gly Asp Val Leu Leu Asp Glu Ala Leu Lys His Val Lys Glu Thr Gln 
    130                 135                 140                 


Pro Pro Glu Thr Val Gln Asn Trp Ile Glu Leu Leu Ser Gly Glu Thr 
145                 150                 155                 160 


Trp Asn Pro Leu Lys Leu His Tyr Gln Leu Arg Asn Val Arg Glu Arg 
                165                 170                 175     


Leu Ala Lys Asn Leu Val Glu Lys Gly Val Leu Thr Thr Glu Lys Gln 
            180                 185                 190         


Asn Phe Leu Leu Phe Asp Met Thr Thr His Pro Leu Thr Asn Asn Asn 
        195                 200                 205             


Ile Lys Gln Arg Leu Ile Lys Lys Val Gln Glu Ala Val Leu Asp Lys 
    210                 215                 220                 


Trp Val Asn Asp Pro His Arg Met Asp Arg Arg Leu Leu Ala Leu Ile 
225                 230                 235                 240 


Tyr Leu Ala His Ala Ser Asp Val Leu Glu Asn Ala Phe Ala Pro Leu 
                245                 250                 255     


Leu Asp Glu Gln Tyr Asp Leu Ala Thr Lys Arg Val Arg Gln Leu Leu 
            260                 265                 270         


Asp Leu Asp Pro Glu Val Glu Cys Leu Lys Ala Asn Thr Asn Glu Val 
        275                 280                 285             


Leu Trp Ala Val Val Ala Ala Phe Thr Lys 
    290                 295             


<210>  3407
<211>  651
<212>  PRT
<213>  homo sapiens

<400>  3407

Met Gly Pro Ala Ser Pro Ala Ala Arg Gly Leu Ser Arg Arg Pro Gly 
1               5                   10                  15      


Gln Pro Pro Leu Pro Leu Leu Leu Pro Leu Leu Leu Leu Leu Leu Arg 
            20                  25                  30          


Ala Gln Pro Ala Ile Gly Ser Leu Ala Gly Gly Ser Pro Gly Ala Ala 
        35                  40                  45              


Glu Ala Pro Gly Ser Ala Gln Val Ala Gly Leu Cys Gly Arg Leu Thr 
    50                  55                  60                  


Leu His Arg Asp Leu Arg Thr Gly Arg Trp Glu Pro Asp Pro Gln Arg 
65                  70                  75                  80  


Ser Arg Arg Cys Leu Arg Asp Pro Gln Arg Val Leu Glu Tyr Cys Arg 
                85                  90                  95      


Gln Met Tyr Pro Glu Leu Gln Ile Ala Arg Val Glu Gln Ala Thr Gln 
            100                 105                 110         


Ala Ile Pro Met Glu Arg Trp Cys Gly Gly Ser Arg Ser Gly Ser Cys 
        115                 120                 125             


Ala His Pro His His Gln Val Val Pro Phe Arg Cys Leu Pro Gly Glu 
    130                 135                 140                 


Phe Val Ser Glu Ala Leu Leu Val Pro Glu Gly Cys Arg Phe Leu His 
145                 150                 155                 160 


Gln Glu Arg Met Asp Gln Cys Glu Ser Ser Thr Arg Arg His Gln Glu 
                165                 170                 175     


Ala Gln Glu Ala Cys Ser Ser Gln Gly Leu Ile Leu His Gly Ser Gly 
            180                 185                 190         


Met Leu Leu Pro Cys Gly Ser Asp Arg Phe Arg Gly Val Glu Tyr Val 
        195                 200                 205             


Cys Cys Pro Pro Pro Gly Thr Pro Asp Pro Ser Gly Thr Ala Val Gly 
    210                 215                 220                 


Asp Pro Ser Thr Arg Ser Trp Pro Pro Gly Ser Arg Val Glu Gly Ala 
225                 230                 235                 240 


Glu Asp Glu Glu Glu Glu Glu Ser Phe Pro Gln Pro Val Asp Asp Tyr 
                245                 250                 255     


Phe Val Glu Pro Pro Gln Ala Glu Glu Glu Glu Glu Thr Val Pro Pro 
            260                 265                 270         


Pro Ser Ser His Thr Leu Ala Val Val Gly Lys Val Thr Pro Thr Pro 
        275                 280                 285             


Arg Pro Thr Asp Gly Val Asp Ile Tyr Phe Gly Met Pro Gly Glu Ile 
    290                 295                 300                 


Ser Glu His Glu Gly Phe Leu Arg Ala Lys Met Asp Leu Glu Glu Arg 
305                 310                 315                 320 


Arg Met Arg Gln Ile Asn Glu Val Met Arg Glu Trp Ala Met Ala Asp 
                325                 330                 335     


Asn Gln Ser Lys Asn Leu Pro Lys Ala Asp Arg Gln Ala Leu Asn Glu 
            340                 345                 350         


His Phe Gln Ser Ile Leu Gln Thr Leu Glu Glu Gln Val Ser Gly Glu 
        355                 360                 365             


Arg Gln Arg Leu Val Glu Thr His Ala Thr Arg Val Ile Ala Leu Ile 
    370                 375                 380                 


Asn Asp Gln Arg Arg Ala Ala Leu Glu Gly Phe Leu Ala Ala Leu Gln 
385                 390                 395                 400 


Ala Asp Pro Pro Gln Ala Glu Arg Val Leu Leu Ala Leu Arg Arg Tyr 
                405                 410                 415     


Leu Arg Ala Glu Gln Lys Glu Gln Arg His Thr Leu Arg His Tyr Gln 
            420                 425                 430         


His Val Ala Ala Val Asp Pro Glu Lys Ala Gln Gln Met Arg Phe Gln 
        435                 440                 445             


Val His Thr His Leu Gln Val Ile Glu Glu Arg Val Asn Gln Ser Leu 
    450                 455                 460                 


Gly Leu Leu Asp Gln Asn Pro His Leu Ala Gln Glu Leu Arg Pro Gln 
465                 470                 475                 480 


Ile Gln Glu Leu Leu His Ser Glu His Leu Gly Pro Ser Glu Leu Glu 
                485                 490                 495     


Ala Pro Ala Pro Gly Gly Ser Ser Glu Asp Lys Gly Gly Leu Gln Pro 
            500                 505                 510         


Pro Asp Ser Lys Asp Ala Asp Thr Pro Met Thr Leu Pro Lys Gly Ser 
        515                 520                 525             


Thr Glu Gln Asp Ala Ala Ser Pro Glu Lys Glu Lys Met Asn Pro Leu 
    530                 535                 540                 


Glu Gln Tyr Glu Arg Lys Val Asn Ala Ser Val Pro Arg Gly Phe Pro 
545                 550                 555                 560 


Phe His Ser Ser Glu Ile Gln Arg Asp Glu Leu Ala Pro Ala Gly Thr 
                565                 570                 575     


Gly Val Ser Arg Glu Ala Val Ser Gly Leu Leu Ile Met Gly Ala Gly 
            580                 585                 590         


Gly Gly Ser Leu Ile Val Leu Ser Met Leu Leu Leu Arg Arg Lys Lys 
        595                 600                 605             


Pro Tyr Gly Ala Ile Ser His Gly Val Val Glu Val Asp Pro Met Leu 
    610                 615                 620                 


Thr Leu Glu Glu Gln Gln Leu Arg Glu Leu Gln Arg His Gly Tyr Glu 
625                 630                 635                 640 


Asn Pro Thr Tyr Arg Phe Leu Glu Glu Arg Pro 
                645                 650     


<210>  3408
<211>  638
<212>  PRT
<213>  homo sapiens

<400>  3408

Met Ala Thr Gly Ala Asn Ala Thr Pro Leu Asp Phe Pro Ser Lys Lys 
1               5                   10                  15      


Arg Lys Arg Ser Arg Trp Asn Gln Asp Thr Met Glu Gln Lys Thr Val 
            20                  25                  30          


Ile Pro Gly Met Pro Thr Val Ile Pro Pro Gly Leu Thr Arg Glu Gln 
        35                  40                  45              


Glu Arg Ala Tyr Ile Val Gln Leu Gln Ile Glu Asp Leu Thr Arg Lys 
    50                  55                  60                  


Leu Arg Thr Gly Asp Leu Gly Ile Pro Pro Asn Pro Glu Asp Arg Ser 
65                  70                  75                  80  


Pro Ser Pro Glu Pro Ile Tyr Asn Ser Glu Gly Lys Arg Leu Asn Thr 
                85                  90                  95      


Arg Glu Phe Arg Thr Arg Lys Lys Leu Glu Glu Glu Arg His Asn Leu 
            100                 105                 110         


Ile Thr Glu Met Val Ala Leu Asn Pro Asp Phe Lys Pro Pro Ala Asp 
        115                 120                 125             


Tyr Lys Pro Pro Ala Thr Arg Val Ser Asp Lys Val Met Ile Pro Gln 
    130                 135                 140                 


Asp Glu Tyr Pro Glu Ile Asn Phe Val Gly Leu Leu Ile Gly Pro Arg 
145                 150                 155                 160 


Gly Asn Thr Leu Lys Asn Ile Glu Lys Glu Cys Asn Ala Lys Ile Met 
                165                 170                 175     


Ile Arg Gly Lys Gly Ser Val Lys Glu Gly Lys Val Gly Arg Lys Asp 
            180                 185                 190         


Gly Gln Met Leu Pro Gly Glu Asp Glu Pro Leu His Ala Leu Val Thr 
        195                 200                 205             


Ala Asn Thr Met Glu Asn Val Lys Lys Ala Val Glu Gln Ile Arg Asn 
    210                 215                 220                 


Ile Leu Lys Gln Gly Ile Glu Thr Pro Glu Asp Gln Asn Asp Leu Arg 
225                 230                 235                 240 


Lys Met Gln Leu Arg Glu Leu Ala Arg Leu Asn Gly Thr Leu Arg Glu 
                245                 250                 255     


Asp Asp Asn Arg Ile Leu Arg Pro Trp Gln Ser Ser Glu Thr Arg Ser 
            260                 265                 270         


Ile Thr Asn Thr Thr Val Cys Thr Lys Cys Gly Gly Ala Gly His Ile 
        275                 280                 285             


Ala Ser Asp Cys Lys Phe Gln Arg Pro Gly Asp Pro Gln Ser Ala Gln 
    290                 295                 300                 


Asp Lys Ala Arg Met Asp Lys Glu Tyr Leu Ser Leu Met Ala Glu Leu 
305                 310                 315                 320 


Gly Glu Ala Pro Val Pro Ala Ser Val Gly Ser Thr Ser Gly Pro Ala 
                325                 330                 335     


Thr Thr Pro Leu Ala Ser Ala Pro Arg Pro Ala Ala Pro Ala Asn Asn 
            340                 345                 350         


Pro Pro Pro Pro Ser Leu Met Ser Thr Thr Gln Ser Arg Pro Pro Trp 
        355                 360                 365             


Met Asn Ser Gly Pro Ser Glu Ser Arg Pro Tyr His Gly Met His Gly 
    370                 375                 380                 


Gly Gly Pro Gly Gly Pro Gly Gly Gly Pro His Ser Phe Pro His Pro 
385                 390                 395                 400 


Leu Pro Ser Leu Thr Gly Gly His Gly Gly His Pro Met Gln His Asn 
                405                 410                 415     


Pro Asn Gly Pro Pro Pro Pro Trp Met Gln Pro Pro Pro Pro Pro Met 
            420                 425                 430         


Asn Gln Gly Pro His Pro Pro Gly His His Gly Pro Pro Pro Met Asp 
        435                 440                 445             


Gln Tyr Leu Gly Ser Thr Pro Val Gly Ser Gly Val Tyr Arg Leu His 
    450                 455                 460                 


Gln Gly Lys Gly Met Met Pro Pro Pro Pro Met Gly Met Met Pro Pro 
465                 470                 475                 480 


Pro Pro Pro Pro Pro Ser Gly Gln Pro Pro Pro Pro Pro Ser Gly Pro 
                485                 490                 495     


Leu Pro Pro Trp Gln Gln Gln Gln Gln Gln Pro Pro Pro Pro Pro Pro 
            500                 505                 510         


Pro Ser Ser Ser Met Ala Ser Ser Thr Pro Leu Pro Trp Gln Gln Asn 
        515                 520                 525             


Thr Thr Thr Thr Thr Thr Ser Ala Gly Thr Gly Ser Ile Pro Pro Trp 
    530                 535                 540                 


Gln Gln Gln Gln Ala Ala Ala Ala Ala Ser Pro Gly Ala Pro Gln Met 
545                 550                 555                 560 


Gln Gly Asn Pro Thr Met Val Pro Leu Pro Pro Gly Val Gln Pro Pro 
                565                 570                 575     


Leu Pro Pro Gly Ala Pro Pro Pro Pro Pro Pro Pro Pro Pro Gly Ser 
            580                 585                 590         


Ala Gly Met Met Ile Pro Pro Arg Gly Gly Asp Gly Pro Ser His Glu 
        595                 600                 605             


Ser Glu Asp Phe Pro Arg Pro Leu Val Thr Leu Pro Gly Arg Gln Pro 
    610                 615                 620                 


Gln Gln Arg Pro Trp Trp Thr Gly Trp Phe Gly Lys Ala Ala 
625                 630                 635             


<210>  3409
<211>  354
<212>  PRT
<213>  homo sapiens

<400>  3409

Met Pro Arg Arg Ser Leu His Ala Ala Ala Val Leu Leu Leu Val Ile 
1               5                   10                  15      


Leu Lys Glu Gln Pro Ser Ser Pro Ala Pro Val Asn Gly Ser Lys Trp 
            20                  25                  30          


Thr Tyr Phe Gly Pro Asp Gly Glu Asn Ser Trp Ser Lys Lys Tyr Pro 
        35                  40                  45              


Ser Cys Gly Gly Leu Leu Gln Ser Pro Ile Asp Leu His Ser Asp Ile 
    50                  55                  60                  


Leu Gln Tyr Asp Ala Ser Leu Thr Pro Leu Glu Phe Gln Gly Tyr Asn 
65                  70                  75                  80  


Leu Ser Ala Asn Lys Gln Phe Leu Leu Thr Asn Asn Gly His Ser Val 
                85                  90                  95      


Lys Leu Asn Leu Pro Ser Asp Met His Ile Gln Gly Leu Gln Ser Arg 
            100                 105                 110         


Tyr Ser Ala Thr Gln Leu His Leu His Trp Gly Asn Pro Asn Asp Pro 
        115                 120                 125             


His Gly Ser Glu His Thr Val Ser Gly Gln His Phe Ala Ala Glu Leu 
    130                 135                 140                 


His Ile Val His Tyr Asn Ser Asp Leu Tyr Pro Asp Ala Ser Thr Ala 
145                 150                 155                 160 


Ser Asn Lys Ser Glu Gly Leu Ala Val Leu Ala Val Leu Ile Glu Met 
                165                 170                 175     


Gly Ser Phe Asn Pro Ser Tyr Asp Lys Ile Phe Ser His Leu Gln His 
            180                 185                 190         


Val Lys Tyr Lys Gly Gln Glu Ala Phe Val Pro Gly Phe Asn Ile Glu 
        195                 200                 205             


Glu Leu Leu Pro Glu Arg Thr Ala Glu Tyr Tyr Arg Tyr Arg Gly Ser 
    210                 215                 220                 


Leu Thr Thr Pro Pro Cys Asn Pro Thr Val Leu Trp Thr Val Phe Arg 
225                 230                 235                 240 


Asn Pro Val Gln Ile Ser Gln Glu Gln Leu Leu Ala Leu Glu Thr Ala 
                245                 250                 255     


Leu Tyr Cys Thr His Met Asp Asp Pro Ser Pro Arg Glu Met Ile Asn 
            260                 265                 270         


Asn Phe Arg Gln Val Gln Lys Phe Asp Glu Arg Leu Val Tyr Thr Ser 
        275                 280                 285             


Phe Ser Gln Val Gln Val Cys Thr Ala Ala Gly Leu Ser Leu Gly Ile 
    290                 295                 300                 


Ile Leu Ser Leu Ala Leu Ala Gly Ile Leu Gly Ile Cys Ile Val Val 
305                 310                 315                 320 


Val Val Ser Ile Trp Leu Phe Arg Arg Lys Ser Ile Lys Lys Gly Asp 
                325                 330                 335     


Asn Lys Gly Val Ile Tyr Lys Pro Ala Thr Lys Met Glu Thr Glu Ala 
            340                 345                 350         


His Ala 
        


<210>  3410
<211>  808
<212>  PRT
<213>  homo sapiens

<400>  3410

Met Gly Ala Pro Ala Cys Ala Leu Ala Leu Cys Val Ala Val Ala Ile 
1               5                   10                  15      


Val Ala Gly Ala Ser Ser Glu Ser Leu Gly Thr Glu Gln Arg Val Val 
            20                  25                  30          


Gly Arg Ala Ala Glu Val Pro Gly Pro Glu Pro Gly Gln Gln Glu Gln 
        35                  40                  45              


Leu Val Phe Gly Ser Gly Asp Ala Val Glu Leu Ser Cys Pro Pro Pro 
    50                  55                  60                  


Gly Gly Gly Pro Met Gly Pro Thr Val Trp Val Lys Asp Gly Thr Gly 
65                  70                  75                  80  


Leu Val Pro Ser Glu Arg Val Leu Val Gly Pro Gln Arg Leu Gln Val 
                85                  90                  95      


Leu Asn Ala Ser His Glu Asp Ser Gly Ala Tyr Ser Cys Arg Gln Arg 
            100                 105                 110         


Leu Thr Gln Arg Val Leu Cys His Phe Ser Val Arg Val Thr Asp Ala 
        115                 120                 125             


Pro Ser Ser Gly Asp Asp Glu Asp Gly Glu Asp Glu Ala Glu Asp Thr 
    130                 135                 140                 


Gly Val Asp Thr Gly Ala Pro Tyr Trp Thr Arg Pro Glu Arg Met Asp 
145                 150                 155                 160 


Lys Lys Leu Leu Ala Val Pro Ala Ala Asn Thr Val Arg Phe Arg Cys 
                165                 170                 175     


Pro Ala Ala Gly Asn Pro Thr Pro Ser Ile Ser Trp Leu Lys Asn Gly 
            180                 185                 190         


Arg Glu Phe Arg Gly Glu His Arg Ile Gly Gly Ile Lys Leu Arg His 
        195                 200                 205             


Gln Gln Trp Ser Leu Val Met Glu Ser Val Val Pro Ser Asp Arg Gly 
    210                 215                 220                 


Asn Tyr Thr Cys Val Val Glu Asn Lys Phe Gly Ser Ile Arg Gln Thr 
225                 230                 235                 240 


Tyr Thr Leu Asp Val Leu Glu Arg Ser Pro His Arg Pro Ile Leu Gln 
                245                 250                 255     


Ala Gly Leu Pro Ala Asn Gln Thr Ala Val Leu Gly Ser Asp Val Glu 
            260                 265                 270         


Phe His Cys Lys Val Tyr Ser Asp Ala Gln Pro His Ile Gln Trp Leu 
        275                 280                 285             


Lys His Val Glu Val Asn Gly Ser Lys Val Gly Pro Asp Gly Thr Pro 
    290                 295                 300                 


Tyr Val Thr Val Leu Lys Ser Trp Ile Ser Glu Ser Val Glu Ala Asp 
305                 310                 315                 320 


Val Arg Leu Arg Leu Ala Asn Val Ser Glu Arg Asp Gly Gly Glu Tyr 
                325                 330                 335     


Leu Cys Arg Ala Thr Asn Phe Ile Gly Val Ala Glu Lys Ala Phe Trp 
            340                 345                 350         


Leu Ser Val His Gly Pro Arg Ala Ala Glu Glu Glu Leu Val Glu Ala 
        355                 360                 365             


Asp Glu Ala Gly Ser Val Tyr Ala Gly Ile Leu Ser Tyr Gly Val Gly 
    370                 375                 380                 


Phe Phe Leu Phe Ile Leu Val Val Ala Ala Val Thr Leu Cys Arg Leu 
385                 390                 395                 400 


Arg Ser Pro Pro Lys Lys Gly Leu Gly Ser Pro Thr Val His Lys Ile 
                405                 410                 415     


Ser Arg Phe Pro Leu Lys Arg Gln Val Ser Leu Glu Ser Asn Ala Ser 
            420                 425                 430         


Met Ser Ser Asn Thr Pro Leu Val Arg Ile Ala Arg Leu Ser Ser Gly 
        435                 440                 445             


Glu Gly Pro Thr Leu Ala Asn Val Ser Glu Leu Glu Leu Pro Ala Asp 
    450                 455                 460                 


Pro Lys Trp Glu Leu Ser Arg Ala Arg Leu Thr Leu Gly Lys Pro Leu 
465                 470                 475                 480 


Gly Glu Gly Cys Phe Gly Gln Val Val Met Ala Glu Ala Ile Gly Ile 
                485                 490                 495     


Asp Lys Asp Arg Ala Ala Lys Pro Val Thr Val Ala Val Lys Met Leu 
            500                 505                 510         


Lys Asp Asp Ala Thr Asp Lys Asp Leu Ser Asp Leu Val Ser Glu Met 
        515                 520                 525             


Glu Met Met Lys Met Ile Gly Lys His Lys Asn Ile Ile Asn Leu Leu 
    530                 535                 540                 


Gly Ala Cys Thr Gln Gly Gly Pro Leu Tyr Val Leu Val Glu Tyr Ala 
545                 550                 555                 560 


Ala Lys Gly Asn Leu Arg Glu Phe Leu Arg Ala Arg Arg Pro Pro Gly 
                565                 570                 575     


Leu Asp Tyr Ser Phe Asp Thr Cys Lys Pro Pro Glu Glu Gln Leu Thr 
            580                 585                 590         


Phe Lys Asp Leu Val Ser Cys Ala Tyr Gln Val Ala Arg Gly Met Glu 
        595                 600                 605             


Tyr Leu Ala Ser Gln Lys Cys Ile His Arg Asp Leu Ala Ala Arg Asn 
    610                 615                 620                 


Val Leu Val Thr Glu Asp Asn Val Met Lys Ile Ala Asp Phe Gly Leu 
625                 630                 635                 640 


Ala Arg Asp Val His Asn Leu Asp Tyr Tyr Lys Lys Thr Thr Asn Gly 
                645                 650                 655     


Arg Leu Pro Val Lys Trp Met Ala Pro Glu Ala Leu Phe Asp Arg Val 
            660                 665                 670         


Tyr Thr His Gln Ser Asp Val Trp Ser Phe Gly Val Leu Leu Trp Glu 
        675                 680                 685             


Ile Phe Thr Leu Gly Gly Ser Pro Tyr Pro Gly Ile Pro Val Glu Glu 
    690                 695                 700                 


Leu Phe Lys Leu Leu Lys Glu Gly His Arg Met Asp Lys Pro Ala Asn 
705                 710                 715                 720 


Cys Thr His Asp Leu Tyr Met Ile Met Arg Glu Cys Trp His Ala Ala 
                725                 730                 735     


Pro Ser Gln Arg Pro Thr Phe Lys Gln Leu Val Glu Asp Leu Asp Arg 
            740                 745                 750         


Val Leu Thr Val Thr Ser Thr Asp Glu Tyr Leu Asp Leu Ser Ala Pro 
        755                 760                 765             


Phe Glu Gln Tyr Ser Pro Gly Gly Gln Asp Thr Pro Ser Ser Ser Ser 
    770                 775                 780                 


Ser Gly Asp Asp Ser Val Phe Ala His Asp Leu Leu Pro Pro Ala Pro 
785                 790                 795                 800 


Pro Ser Ser Gly Gly Ser Arg Thr 
                805             


<210>  3411
<211>  1430
<212>  PRT
<213>  homo sapiens

<400>  3411

Met Ser Arg Pro Ser Ser Val Ser Pro Arg Gln Pro Ala Pro Gly Gly 
1               5                   10                  15      


Gly Gly Gly Gly Gly Pro Ser Pro Cys Gly Pro Gly Gly Gly Gly Arg 
            20                  25                  30          


Ala Lys Gly Leu Lys Asp Ile Arg Ile Asp Glu Glu Val Lys Ile Ala 
        35                  40                  45              


Val Asn Ile Ala Leu Glu Arg Phe Arg Tyr Gly Asp Gln Arg Glu Met 
    50                  55                  60                  


Glu Phe Pro Ser Ser Leu Thr Ser Thr Glu Arg Ala Phe Ile His Arg 
65                  70                  75                  80  


Leu Ser Gln Ser Leu Gly Leu Val Ser Lys Ser Lys Gly Lys Gly Ala 
                85                  90                  95      


Asn Arg Tyr Leu Thr Val Lys Lys Lys Asp Gly Ser Glu Thr Ala His 
            100                 105                 110         


Ala Met Met Thr Cys Asn Leu Thr His Asn Thr Lys His Ala Val Arg 
        115                 120                 125             


Ser Leu Ile Gln Arg Phe Pro Val Thr Asn Lys Glu Arg Thr Glu Leu 
    130                 135                 140                 


Leu Pro Lys Thr Glu Arg Gly Asn Val Phe Ala Val Glu Ala Glu Asn 
145                 150                 155                 160 


Arg Glu Met Ser Lys Thr Ser Gly Arg Leu Asn Asn Gly Ile Pro Gln 
                165                 170                 175     


Ile Pro Val Lys Arg Gly Glu Ser Glu Phe Asp Ser Phe Arg Gln Ser 
            180                 185                 190         


Leu Pro Val Phe Glu Lys Gln Glu Glu Ile Val Lys Ile Ile Lys Glu 
        195                 200                 205             


Asn Lys Val Val Leu Ile Val Gly Glu Thr Gly Ser Gly Lys Thr Thr 
    210                 215                 220                 


Gln Ile Pro Gln Phe Leu Leu Asp Asp Cys Phe Lys Asn Gly Ile Pro 
225                 230                 235                 240 


Cys Arg Ile Phe Cys Thr Gln Pro Arg Arg Leu Ala Ala Ile Ala Val 
                245                 250                 255     


Ala Glu Arg Val Ala Ala Glu Arg Arg Glu Arg Ile Gly Gln Thr Ile 
            260                 265                 270         


Gly Tyr Gln Ile Arg Leu Glu Ser Arg Val Ser Pro Lys Thr Leu Leu 
        275                 280                 285             


Thr Phe Cys Thr Asn Gly Val Leu Leu Arg Thr Leu Met Ala Gly Asp 
    290                 295                 300                 


Ser Thr Leu Ser Thr Val Thr His Val Ile Val Asp Glu Val His Glu 
305                 310                 315                 320 


Arg Asp Arg Phe Ser Asp Phe Leu Leu Thr Lys Leu Arg Asp Leu Leu 
                325                 330                 335     


Gln Lys His Pro Thr Leu Lys Leu Ile Leu Ser Ser Ala Ala Leu Asp 
            340                 345                 350         


Val Asn Leu Phe Ile Arg Tyr Phe Gly Ser Cys Pro Val Ile Tyr Ile 
        355                 360                 365             


Gln Gly Arg Pro Phe Glu Val Lys Glu Met Phe Leu Glu Asp Ile Leu 
    370                 375                 380                 


Arg Thr Thr Gly Tyr Thr Asn Lys Glu Met Leu Lys Tyr Lys Lys Glu 
385                 390                 395                 400 


Lys Gln Gln Glu Glu Lys Gln Gln Thr Thr Leu Thr Glu Trp Tyr Ser 
                405                 410                 415     


Ala Gln Glu Asn Ser Phe Lys Pro Glu Ser Gln Arg Gln Arg Thr Val 
            420                 425                 430         


Leu Asn Val Thr Asp Glu Tyr Asp Leu Leu Asp Asp Gly Gly Asp Ala 
        435                 440                 445             


Val Phe Ser Gln Leu Thr Glu Lys Asp Val Asn Cys Leu Glu Pro Trp 
    450                 455                 460                 


Leu Ile Lys Glu Met Asp Ala Cys Leu Ser Asp Ile Trp Leu His Lys 
465                 470                 475                 480 


Asp Ile Asp Ala Phe Ala Gln Val Phe His Leu Ile Leu Thr Glu Asn 
                485                 490                 495     


Val Ser Val Asp Tyr Arg His Ser Glu Thr Ser Ala Thr Ala Leu Met 
            500                 505                 510         


Val Ala Ala Gly Arg Gly Phe Ala Ser Gln Val Glu Gln Leu Ile Ser 
        515                 520                 525             


Met Gly Ala Asn Val His Ser Lys Ala Ser Asn Gly Trp Met Ala Leu 
    530                 535                 540                 


Asp Trp Ala Lys His Phe Gly Gln Thr Glu Ile Val Asp Leu Leu Glu 
545                 550                 555                 560 


Ser Tyr Ser Ala Thr Leu Glu Phe Gly Asn Leu Asp Glu Ser Ser Leu 
                565                 570                 575     


Val Gln Thr Asn Gly Ser Asp Leu Ser Ala Glu Asp Arg Glu Leu Leu 
            580                 585                 590         


Lys Ala Tyr His His Ser Phe Asp Asp Glu Lys Val Asp Leu Asp Leu 
        595                 600                 605             


Ile Met His Leu Leu Tyr Asn Ile Cys His Ser Cys Asp Ala Gly Ala 
    610                 615                 620                 


Val Leu Ile Phe Leu Pro Gly Tyr Asp Glu Ile Val Gly Leu Arg Asp 
625                 630                 635                 640 


Arg Ile Leu Phe Asp Asp Lys Arg Phe Ala Asp Ser Thr His Arg Tyr 
                645                 650                 655     


Gln Val Phe Met Leu His Ser Asn Met Gln Thr Ser Asp Gln Lys Lys 
            660                 665                 670         


Val Leu Lys Asn Pro Pro Ala Gly Val Arg Lys Ile Ile Leu Ser Thr 
        675                 680                 685             


Asn Ile Ala Glu Thr Ser Ile Thr Val Asn Asp Val Val Phe Val Ile 
    690                 695                 700                 


Asp Ser Gly Lys Val Lys Glu Lys Ser Phe Asp Ala Leu Asn Phe Val 
705                 710                 715                 720 


Thr Met Leu Lys Met Val Trp Ile Ser Lys Ala Ser Ala Ile Gln Arg 
                725                 730                 735     


Lys Gly Arg Ala Gly Arg Cys Arg Pro Gly Ile Cys Phe Arg Leu Phe 
            740                 745                 750         


Ser Arg Leu Arg Phe Gln Asn Met Leu Glu Phe Gln Thr Pro Glu Leu 
        755                 760                 765             


Leu Arg Met Pro Leu Gln Glu Leu Cys Leu His Thr Lys Leu Leu Ala 
    770                 775                 780                 


Pro Val Asn Cys Pro Ile Ala Asp Phe Leu Met Lys Ala Pro Glu Pro 
785                 790                 795                 800 


Pro Pro Ala Leu Ile Val Arg Asn Ala Val Gln Met Leu Lys Thr Ile 
                805                 810                 815     


Asp Ala Met Asp Thr Trp Glu Asp Leu Thr Glu Leu Gly Tyr His Leu 
            820                 825                 830         


Ala Asp Leu Pro Val Glu Pro His Leu Gly Lys Met Val Leu Cys Ala 
        835                 840                 845             


Val Val Leu Lys Cys Leu Asp Pro Ile Leu Thr Ile Ala Cys Thr Leu 
    850                 855                 860                 


Ala Tyr Arg Asp Pro Phe Val Leu Pro Thr Gln Ala Ser Gln Lys Arg 
865                 870                 875                 880 


Ala Ala Met Leu Cys Arg Lys Arg Phe Thr Ala Gly Ala Phe Ser Asp 
                885                 890                 895     


His Met Ala Leu Leu Arg Ala Phe Gln Ala Trp Gln Lys Ala Arg Ser 
            900                 905                 910         


Asp Gly Trp Glu Arg Ala Phe Cys Glu Lys Asn Phe Leu Ser Gln Ala 
        915                 920                 925             


Thr Met Glu Ile Ile Ile Gly Met Arg Thr Gln Leu Leu Gly Gln Leu 
    930                 935                 940                 


Arg Ala Ser Gly Phe Val Arg Ala Arg Gly Gly Gly Asp Ile Arg Asp 
945                 950                 955                 960 


Val Asn Thr Asn Ser Glu Asn Trp Ala Val Val Lys Ala Ala Leu Val 
                965                 970                 975     


Ala Gly Met Tyr Pro Asn Leu Val His Val Asp Arg Glu Asn Leu Val 
            980                 985                 990         


Leu Thr Gly Pro Lys Glu Lys Lys  Val Arg Phe His Pro  Ala Ser Val 
        995                 1000                 1005             


Leu Ser  Gln Pro Gln Tyr Lys  Lys Ile Pro Pro Ala  Asn Gly Gln 
    1010                 1015                 1020             


Ala Ala  Ala Ile Lys Ala Leu  Pro Thr Asp Trp Leu  Ile Tyr Asp 
    1025                 1030                 1035             


Glu Met  Thr Arg Ala His Arg  Ile Ala Asn Ile Arg  Cys Cys Ser 
    1040                 1045                 1050             


Ala Val  Thr Pro Val Thr Ile  Leu Val Phe Cys Gly  Pro Ala Arg 
    1055                 1060                 1065             


Leu Ala  Ser Asn Ala Leu Gln  Glu Pro Ser Ser Phe  Arg Val Asp 
    1070                 1075                 1080             


Gly Ile  Pro Asn Asp Ser Ser  Asp Ser Glu Met Glu  Asp Lys Thr 
    1085                 1090                 1095             


Thr Ala  Asn Leu Ala Ala Leu  Lys Leu Asp Glu Trp  Leu His Phe 
    1100                 1105                 1110             


Thr Leu  Glu Pro Glu Ala Ala  Ser Leu Leu Leu Gln  Leu Arg Gln 
    1115                 1120                 1125             


Lys Trp  His Ser Leu Phe Leu  Arg Arg Met Arg Ala  Pro Ser Lys 
    1130                 1135                 1140             


Pro Trp  Ser Gln Val Asp Glu  Ala Thr Ile Arg Ala  Ile Ile Ala 
    1145                 1150                 1155             


Val Leu  Ser Thr Glu Glu Gln  Ser Ala Gly Leu Gln  Gln Pro Ser 
    1160                 1165                 1170             


Gly Ile  Gly Gln Arg Pro Arg  Pro Met Ser Ser Glu  Glu Leu Pro 
    1175                 1180                 1185             


Leu Ala  Ser Ser Trp Arg Ser  Asn Asn Ser Arg Lys  Ser Ser Ala 
    1190                 1195                 1200             


Asp Thr  Glu Phe Ser Asp Glu  Cys Thr Thr Ala Glu  Arg Val Leu 
    1205                 1210                 1215             


Met Lys  Ser Pro Ser Pro Ala  Leu His Pro Pro Gln  Lys Tyr Lys 
    1220                 1225                 1230             


Asp Arg  Gly Ile Leu His Pro  Lys Arg Gly Thr Glu  Asp Arg Ser 
    1235                 1240                 1245             


Asp Gln  Ser Ser Leu Lys Ser  Thr Asp Ser Ser Ser  Tyr Pro Ser 
    1250                 1255                 1260             


Pro Cys  Ala Ser Pro Ser Pro  Pro Ser Ser Gly Lys  Gly Ser Lys 
    1265                 1270                 1275             


Ser Pro  Ser Pro Arg Pro Asn  Met Pro Val Arg Tyr  Phe Ile Met 
    1280                 1285                 1290             


Lys Ser  Ser Asn Leu Arg Asn  Leu Glu Ile Ser Gln  Gln Lys Gly 
    1295                 1300                 1305             


Ile Trp  Ser Thr Thr Pro Ser  Asn Glu Arg Lys Leu  Asn Arg Ala 
    1310                 1315                 1320             


Phe Trp  Glu Ser Ser Ile Val  Tyr Leu Val Phe Ser  Val Gln Gly 
    1325                 1330                 1335             


Ser Gly  His Phe Gln Gly Phe  Ser Arg Met Ser Ser  Glu Ile Gly 
    1340                 1345                 1350             


Arg Glu  Lys Ser Gln Asp Trp  Gly Ser Ala Gly Leu  Gly Gly Val 
    1355                 1360                 1365             


Phe Lys  Val Glu Trp Ile Arg  Lys Glu Ser Leu Pro  Phe Gln Phe 
    1370                 1375                 1380             


Ala His  His Leu Leu Asn Pro  Trp Asn Asp Asn Lys  Lys Val Gln 
    1385                 1390                 1395             


Ile Ser  Arg Asp Gly Gln Glu  Leu Glu Pro Leu Val  Gly Glu Gln 
    1400                 1405                 1410             


Leu Leu  Gln Leu Trp Glu Arg  Leu Pro Leu Gly Glu  Lys Asn Thr 
    1415                 1420                 1425             


Thr Asp  
    1430 


<210>  3412
<211>  414
<212>  PRT
<213>  homo sapiens

<400>  3412

Met Ala Ser Gly Asp Thr Leu Tyr Ile Ala Thr Asp Gly Ser Glu Met 
1               5                   10                  15      


Pro Ala Glu Ile Val Glu Leu His Glu Ile Glu Val Glu Thr Ile Pro 
            20                  25                  30          


Val Glu Thr Ile Glu Thr Thr Val Val Gly Glu Glu Glu Glu Glu Asp 
        35                  40                  45              


Asp Asp Asp Glu Asp Gly Gly Gly Gly Asp His Gly Gly Gly Gly Gly 
    50                  55                  60                  


His Gly His Ala Gly His His His His His His His His His His His 
65                  70                  75                  80  


Pro Pro Met Ile Ala Leu Gln Pro Leu Val Thr Asp Asp Pro Thr Gln 
                85                  90                  95      


Val His His His Gln Glu Val Ile Leu Val Gln Thr Arg Glu Glu Val 
            100                 105                 110         


Val Gly Gly Asp Asp Ser Asp Gly Leu Arg Ala Glu Asp Gly Phe Glu 
        115                 120                 125             


Asp Gln Ile Leu Ile Pro Val Pro Ala Pro Ala Gly Gly Asp Asp Asp 
    130                 135                 140                 


Tyr Ile Glu Gln Thr Leu Val Thr Val Ala Ala Ala Gly Lys Ser Gly 
145                 150                 155                 160 


Gly Gly Gly Ser Ser Ser Ser Gly Gly Gly Arg Val Lys Lys Gly Gly 
                165                 170                 175     


Gly Lys Lys Ser Gly Lys Lys Ser Tyr Leu Ser Gly Gly Ala Gly Ala 
            180                 185                 190         


Ala Gly Gly Gly Gly Ala Asp Pro Gly Asn Lys Lys Trp Glu Gln Lys 
        195                 200                 205             


Gln Val Gln Ile Lys Thr Leu Glu Gly Glu Phe Ser Val Thr Met Trp 
    210                 215                 220                 


Ser Ser Asp Glu Lys Lys Asp Ile Asp His Glu Thr Val Val Glu Glu 
225                 230                 235                 240 


Gln Ile Ile Gly Glu Asn Ser Pro Pro Asp Tyr Ser Glu Tyr Met Thr 
                245                 250                 255     


Gly Lys Lys Leu Pro Pro Gly Gly Ile Pro Gly Ile Asp Leu Ser Asp 
            260                 265                 270         


Pro Lys Gln Leu Ala Glu Phe Ala Arg Met Lys Pro Arg Lys Ile Lys 
        275                 280                 285             


Glu Asp Asp Ala Pro Arg Thr Ile Ala Cys Pro His Lys Gly Cys Thr 
    290                 295                 300                 


Lys Met Phe Arg Asp Asn Ser Ala Met Arg Lys His Leu His Thr His 
305                 310                 315                 320 


Gly Pro Arg Val His Val Cys Ala Glu Cys Gly Lys Ala Phe Val Glu 
                325                 330                 335     


Ser Ser Lys Leu Lys Arg His Gln Leu Val His Thr Gly Glu Lys Pro 
            340                 345                 350         


Phe Gln Cys Thr Phe Glu Gly Cys Gly Lys Arg Phe Ser Leu Asp Phe 
        355                 360                 365             


Asn Leu Arg Thr His Val Arg Ile His Thr Gly Asp Arg Pro Tyr Val 
    370                 375                 380                 


Cys Pro Phe Asp Gly Cys Asn Lys Lys Phe Ala Gln Ser Thr Asn Leu 
385                 390                 395                 400 


Lys Ser His Ile Leu Thr His Ala Lys Ala Lys Asn Asn Gln 
                405                 410                 


<210>  3413
<211>  1171
<212>  PRT
<213>  homo sapiens

<400>  3413

Met Glu Asn Asn Leu Lys Thr Cys Pro Lys Glu Asp Gly Asp Phe Val 
1               5                   10                  15      


Ser Asp Lys Ile Lys Phe Lys Ile Glu Glu Glu Asp Asp Asp Gly Ile 
            20                  25                  30          


Pro Pro Asp Ser Leu Glu Arg Met Asp Phe Lys Ser Glu Gln Glu Asp 
        35                  40                  45              


Met Lys Gln Thr Asp Ser Gly Gly Glu Arg Ala Gly Leu Gly Gly Thr 
    50                  55                  60                  


Gly Cys Ser Cys Lys Pro Pro Gly Lys Tyr Leu Ser Ala Glu Ser Glu 
65                  70                  75                  80  


Asp Asp Tyr Gly Ala Leu Phe Ser Gln Tyr Ser Ser Thr Leu Tyr Asp 
                85                  90                  95      


Val Ala Met Glu Ala Val Thr Gln Ser Leu Leu Ser Ser Arg Asn Met 
            100                 105                 110         


Ser Ser Arg Lys Lys Ser Pro Ala Trp Lys His Phe Phe Ile Ser Pro 
        115                 120                 125             


Arg Asp Ser Thr Lys Ala Ile Cys Met Tyr Cys Val Lys Glu Phe Ser 
    130                 135                 140                 


Arg Gly Lys Asn Glu Lys Asp Leu Ser Thr Ser Cys Leu Met Arg His 
145                 150                 155                 160 


Val Arg Arg Ala His Pro Thr Val Leu Ile Gln Glu Asn Gly Ser Val 
                165                 170                 175     


Ser Ala Val Ser Ser Phe Pro Ser Pro Ser Leu Leu Leu Pro Pro Gln 
            180                 185                 190         


Pro Ala Asp Ala Gly Asp Leu Ser Thr Ile Leu Ser Pro Ile Lys Leu 
        195                 200                 205             


Val Gln Lys Val Ala Ser Lys Ile Pro Ser Pro Asp Arg Ile Thr Glu 
    210                 215                 220                 


Glu Ser Val Ser Val Val Ser Ser Glu Glu Ile Ser Ser Asp Met Ser 
225                 230                 235                 240 


Val Ser Glu Lys Cys Gly Arg Glu Glu Ala Leu Val Gly Ser Ser Pro 
                245                 250                 255     


His Leu Pro Ala Leu His Tyr Asp Glu Pro Ala Glu Asn Leu Ala Glu 
            260                 265                 270         


Lys Ser Leu Pro Leu Pro Lys Ser Thr Ser Gly Ser Arg Arg Arg Ser 
        275                 280                 285             


Ala Val Trp Lys His Phe Tyr Leu Ser Pro Leu Asp Asn Ser Lys Ala 
    290                 295                 300                 


Val Cys Ile His Cys Met Asn Glu Phe Ser Arg Gly Lys Asn Gly Lys 
305                 310                 315                 320 


Asp Leu Gly Thr Ser Cys Leu Ile Arg His Met Trp Arg Ala His Arg 
                325                 330                 335     


Ala Ile Val Leu Gln Glu Asn Gly Gly Thr Gly Ile Pro Pro Leu Tyr 
            340                 345                 350         


Ser Thr Pro Pro Thr Leu Leu Pro Ser Leu Leu Pro Pro Glu Gly Glu 
        355                 360                 365             


Leu Ser Ser Val Ser Ser Ser Pro Val Lys Pro Val Arg Glu Ser Pro 
    370                 375                 380                 


Ser Ala Ser Ser Ser Pro Asp Arg Leu Thr Glu Asp Leu Gln Ser His 
385                 390                 395                 400 


Leu Asn Pro Gly Asp Gly Leu Met Glu Asp Val Ala Ala Phe Ser Ser 
                405                 410                 415     


Ser Asp Asp Ile Gly Glu Ala Ser Ala Ser Ser Pro Glu Lys Gln Gln 
            420                 425                 430         


Ala Asp Gly Leu Ser Pro Arg Leu Phe Glu Ser Gly Ala Ile Phe Gln 
        435                 440                 445             


Gln Asn Lys Lys Val Met Lys Arg Leu Lys Ser Glu Val Trp His His 
    450                 455                 460                 


Phe Ser Leu Ala Pro Met Asp Ser Leu Lys Ala Glu Cys Arg Tyr Cys 
465                 470                 475                 480 


Gly Cys Ala Ile Ser Arg Gly Lys Lys Gly Asp Val Gly Thr Ser Cys 
                485                 490                 495     


Leu Met Arg His Leu Tyr Arg Arg His Pro Glu Val Val Gly Ser Gln 
            500                 505                 510         


Lys Gly Phe Leu Gly Ala Ser Leu Ala Asn Ser Pro Tyr Ala Thr Leu 
        515                 520                 525             


Ala Ser Ala Glu Ser Ser Ser Ser Lys Leu Thr Asp Leu Pro Thr Val 
    530                 535                 540                 


Val Thr Lys Asn Asn Gln Val Met Phe Pro Val Asn Ser Lys Lys Thr 
545                 550                 555                 560 


Ser Lys Leu Trp Asn His Phe Ser Ile Cys Ser Ala Asp Ser Thr Lys 
                565                 570                 575     


Val Val Cys Leu His Cys Gly Arg Thr Ile Ser Arg Gly Lys Lys Pro 
            580                 585                 590         


Thr Asn Leu Gly Thr Ser Cys Leu Leu Arg His Leu Gln Arg Phe His 
        595                 600                 605             


Ser Asn Val Leu Lys Thr Glu Val Ser Glu Thr Ala Arg Pro Ser Ser 
    610                 615                 620                 


Pro Asp Thr Arg Val Pro Arg Gly Thr Glu Leu Ser Gly Ala Ser Ser 
625                 630                 635                 640 


Phe Asp Asp Thr Asn Glu Lys Phe Tyr Asp Ser His Pro Val Ala Lys 
                645                 650                 655     


Lys Ile Thr Ser Leu Ile Ala Glu Met Ile Ala Leu Asp Leu Gln Pro 
            660                 665                 670         


Tyr Ser Phe Val Asp Asn Val Gly Phe Asn Arg Leu Leu Glu Tyr Leu 
        675                 680                 685             


Lys Pro Gln Tyr Ser Leu Pro Ala Pro Ser Tyr Phe Ser Arg Thr Ala 
    690                 695                 700                 


Ile Pro Gly Met Tyr Asp Asn Val Lys Gln Ile Ile Met Ser His Leu 
705                 710                 715                 720 


Lys Glu Ala Glu Ser Gly Val Ile His Phe Thr Ser Gly Ile Trp Met 
                725                 730                 735     


Ser Asn Gln Thr Arg Glu Tyr Leu Thr Leu Thr Ala His Trp Val Ser 
            740                 745                 750         


Phe Glu Ser Pro Ala Arg Pro Arg Cys Asp Asp His His Cys Ser Ala 
        755                 760                 765             


Leu Leu Asp Val Ser Gln Val Asp Cys Asp Tyr Ser Gly Asn Ser Ile 
    770                 775                 780                 


Gln Lys Gln Leu Glu Cys Trp Trp Glu Ala Trp Val Thr Ser Thr Gly 
785                 790                 795                 800 


Leu Gln Val Gly Ile Thr Val Thr Asp Asn Ala Ser Ile Gly Lys Thr 
                805                 810                 815     


Leu Asn Glu Gly Glu His Ser Ser Val Gln Cys Phe Ser His Thr Val 
            820                 825                 830         


Asn Leu Ile Val Ser Glu Ala Ile Lys Ser Gln Arg Met Val Gln Asn 
        835                 840                 845             


Leu Leu Ser Leu Ala Arg Lys Ile Cys Glu Arg Val His Arg Ser Pro 
    850                 855                 860                 


Lys Ala Lys Glu Lys Leu Ala Glu Leu Gln Arg Glu Tyr Ala Leu Pro 
865                 870                 875                 880 


Gln His His Leu Ile Gln Asp Val Pro Ser Lys Trp Ser Thr Ser Phe 
                885                 890                 895     


His Met Leu Glu Arg Leu Ile Glu Gln Lys Arg Ala Ile Asn Glu Met 
            900                 905                 910         


Ser Val Glu Cys Asn Phe Arg Glu Leu Ile Ser Cys Asp Gln Trp Glu 
        915                 920                 925             


Val Met Gln Ser Val Cys Arg Ala Leu Lys Pro Phe Glu Ala Ala Ser 
    930                 935                 940                 


Arg Glu Met Ser Thr Gln Met Ser Thr Leu Ser Gln Val Ile Pro Met 
945                 950                 955                 960 


Val His Ile Leu Asn Arg Lys Val Glu Met Leu Phe Glu Glu Thr Met 
                965                 970                 975     


Gly Ile Asp Thr Met Leu Arg Ser Leu Lys Glu Ala Met Val Ser Arg 
            980                 985                 990         


Leu Ser Ala Thr Leu His Asp Pro  Arg Tyr Val Phe Ala  Thr Leu Leu 
        995                 1000                 1005             


Asp Pro  Arg Tyr Lys Ala Ser  Leu Phe Thr Glu Glu  Glu Ala Glu 
    1010                 1015                 1020             


Gln Tyr  Lys Gln Asp Leu Ile  Arg Glu Leu Glu Leu  Met Asn Ser 
    1025                 1030                 1035             


Thr Ser  Glu Asp Val Ala Ala  Ser His Arg Cys Asp  Ala Gly Ser 
    1040                 1045                 1050             


Pro Ser  Lys Asp Ser Ala Ala  Glu Glu Asn Leu Trp  Ser Leu Val 
    1055                 1060                 1065             


Ala Lys  Val Lys Lys Lys Asp  Pro Arg Glu Lys Leu  Pro Glu Ala 
    1070                 1075                 1080             


Met Val  Leu Ala Tyr Leu Glu  Glu Glu Val Leu Glu  His Ser Cys 
    1085                 1090                 1095             


Asp Pro  Leu Thr Tyr Trp Asn  Leu Lys Lys Ala Ser  Trp Pro Gly 
    1100                 1105                 1110             


Leu Ser  Ala Leu Ala Val Arg  Phe Leu Gly Cys Pro  Pro Ser Ile 
    1115                 1120                 1125             


Val Pro  Ser Glu Lys Leu Phe  Asn Thr Pro Thr Glu  Asn Gly Ser 
    1130                 1135                 1140             


Leu Gly  Gln Ser Arg Leu Met  Met Glu His Phe Glu  Lys Leu Ile 
    1145                 1150                 1155             


Phe Leu  Lys Val Asn Leu Pro  Leu Ile Tyr Phe Gln  Tyr 
    1160                 1165                 1170     


<210>  3414
<211>  168
<212>  PRT
<213>  homo sapiens

<400>  3414

Met Ala Glu Pro Trp Gly Asn Glu Leu Ala Ser Ala Ala Ala Arg Gly 
1               5                   10                  15      


Asp Leu Glu Gln Leu Thr Ser Leu Leu Gln Asn Asn Val Asn Val Asn 
            20                  25                  30          


Ala Gln Asn Gly Phe Gly Arg Thr Ala Leu Gln Val Met Lys Leu Gly 
        35                  40                  45              


Asn Pro Glu Ile Ala Arg Arg Leu Leu Leu Arg Gly Ala Asn Pro Asp 
    50                  55                  60                  


Leu Lys Asp Arg Thr Gly Phe Ala Val Ile His Asp Ala Ala Arg Ala 
65                  70                  75                  80  


Gly Phe Leu Asp Thr Leu Gln Thr Leu Leu Glu Phe Gln Ala Asp Val 
                85                  90                  95      


Asn Ile Glu Asp Asn Glu Gly Asn Leu Pro Leu His Leu Ala Ala Lys 
            100                 105                 110         


Glu Gly His Leu Arg Val Val Glu Phe Leu Val Lys His Thr Ala Ser 
        115                 120                 125             


Asn Val Gly His Arg Asn His Lys Gly Asp Thr Ala Cys Asp Leu Ala 
    130                 135                 140                 


Arg Leu Tyr Gly Arg Asn Glu Val Val Ser Leu Met Gln Ala Asn Gly 
145                 150                 155                 160 


Ala Gly Gly Ala Thr Asn Leu Gln 
                165             


<210>  3415
<211>  947
<212>  PRT
<213>  homo sapiens

<400>  3415

Met Arg Arg Leu Ala Phe Glu Gln Gly Glu Ser Arg Ile Leu Arg Val 
1               5                   10                  15      


Lys Val Val Ser Gly Ile Asp Leu Ala Lys Lys Asp Ile Phe Gly Ala 
            20                  25                  30          


Ser Asp Pro Tyr Val Lys Leu Ser Leu Tyr Val Ala Asp Glu Asn Arg 
        35                  40                  45              


Glu Leu Ala Leu Val Gln Thr Lys Thr Ile Lys Lys Thr Leu Asn Pro 
    50                  55                  60                  


Lys Trp Asn Glu Glu Phe Tyr Phe Arg Val Asn Pro Ser Asn His Arg 
65                  70                  75                  80  


Leu Leu Phe Glu Val Phe Asp Glu Asn Arg Leu Thr Arg Asp Asp Phe 
                85                  90                  95      


Leu Gly Gln Val Asp Val Pro Leu Ser His Leu Pro Thr Glu Asp Pro 
            100                 105                 110         


Thr Met Glu Arg Pro Tyr Thr Phe Lys Asp Phe Leu Leu Arg Pro Arg 
        115                 120                 125             


Ser His Lys Ser Arg Val Lys Gly Phe Leu Arg Leu Lys Met Ala Tyr 
    130                 135                 140                 


Met Pro Lys Asn Gly Gly Gln Asp Glu Glu Asn Ser Asp Gln Arg Asp 
145                 150                 155                 160 


Asp Met Glu His Gly Trp Glu Val Val Asp Ser Asn Asp Ser Ala Ser 
                165                 170                 175     


Gln His Gln Glu Glu Leu Pro Pro Pro Pro Leu Pro Pro Gly Trp Glu 
            180                 185                 190         


Glu Lys Val Asp Asn Leu Gly Arg Thr Tyr Tyr Val Asn His Asn Asn 
        195                 200                 205             


Arg Thr Thr Gln Trp His Arg Pro Ser Leu Met Asp Val Ser Ser Glu 
    210                 215                 220                 


Ser Asp Asn Asn Ile Arg Gln Ile Asn Gln Glu Ala Ala His Arg Arg 
225                 230                 235                 240 


Phe Arg Ser Arg Arg His Ile Ser Glu Asp Leu Glu Pro Glu Pro Ser 
                245                 250                 255     


Glu Gly Gly Asp Val Pro Glu Pro Trp Glu Thr Ile Ser Glu Glu Val 
            260                 265                 270         


Asn Ile Ala Gly Asp Ser Leu Gly Leu Ala Leu Pro Pro Pro Pro Ala 
        275                 280                 285             


Ser Pro Gly Ser Arg Thr Ser Pro Gln Glu Leu Ser Glu Glu Leu Ser 
    290                 295                 300                 


Arg Arg Leu Gln Ile Thr Pro Asp Ser Asn Gly Glu Gln Phe Ser Ser 
305                 310                 315                 320 


Leu Ile Gln Arg Glu Pro Ser Ser Arg Leu Arg Ser Cys Ser Val Thr 
                325                 330                 335     


Asp Ala Val Ala Glu Gln Gly His Leu Pro Pro Pro Ser Val Ala Tyr 
            340                 345                 350         


Val His Thr Thr Pro Gly Leu Pro Ser Gly Trp Glu Glu Arg Lys Asp 
        355                 360                 365             


Ala Lys Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg Thr Thr Thr 
    370                 375                 380                 


Trp Thr Arg Pro Ile Met Gln Leu Ala Glu Asp Gly Ala Ser Gly Ser 
385                 390                 395                 400 


Ala Thr Asn Ser Asn Asn His Leu Ile Glu Pro Gln Ile Arg Arg Pro 
                405                 410                 415     


Arg Ser Leu Ser Ser Pro Thr Val Thr Leu Ser Ala Pro Leu Glu Gly 
            420                 425                 430         


Ala Lys Asp Ser Pro Val Arg Arg Ala Val Lys Asp Thr Leu Ser Asn 
        435                 440                 445             


Pro Gln Ser Pro Gln Pro Ser Pro Tyr Asn Ser Pro Lys Pro Gln His 
    450                 455                 460                 


Lys Val Thr Gln Ser Phe Leu Pro Pro Gly Trp Glu Met Arg Ile Ala 
465                 470                 475                 480 


Pro Asn Gly Arg Pro Phe Phe Ile Asp His Asn Thr Lys Thr Thr Thr 
                485                 490                 495     


Trp Glu Asp Pro Arg Leu Lys Phe Pro Val His Met Arg Ser Lys Thr 
            500                 505                 510         


Ser Leu Asn Pro Asn Asp Leu Gly Pro Leu Pro Pro Gly Trp Glu Glu 
        515                 520                 525             


Arg Ile His Leu Asp Gly Arg Thr Phe Tyr Ile Asp His Asn Ser Lys 
    530                 535                 540                 


Ile Thr Gln Trp Glu Asp Pro Arg Leu Gln Asn Pro Ala Ile Thr Gly 
545                 550                 555                 560 


Pro Ala Val Pro Tyr Ser Arg Glu Phe Lys Gln Lys Tyr Asp Tyr Phe 
                565                 570                 575     


Arg Lys Lys Leu Lys Lys Pro Ala Asp Ile Pro Asn Arg Phe Glu Met 
            580                 585                 590         


Lys Leu His Arg Asn Asn Ile Phe Glu Glu Ser Tyr Arg Arg Ile Met 
        595                 600                 605             


Ser Val Lys Arg Pro Asp Val Leu Lys Ala Arg Leu Trp Ile Glu Phe 
    610                 615                 620                 


Glu Ser Glu Lys Gly Leu Asp Tyr Gly Gly Val Ala Arg Glu Trp Phe 
625                 630                 635                 640 


Phe Leu Leu Ser Lys Glu Met Phe Asn Pro Tyr Tyr Gly Leu Phe Glu 
                645                 650                 655     


Tyr Ser Ala Thr Asp Asn Tyr Thr Leu Gln Ile Asn Pro Asn Ser Gly 
            660                 665                 670         


Leu Cys Asn Glu Asp His Leu Ser Tyr Phe Thr Phe Ile Gly Arg Val 
        675                 680                 685             


Ala Gly Leu Ala Val Phe His Gly Lys Leu Leu Asp Gly Phe Phe Ile 
    690                 695                 700                 


Arg Pro Phe Tyr Lys Met Met Leu Gly Lys Gln Ile Thr Leu Asn Asp 
705                 710                 715                 720 


Met Glu Ser Val Asp Ser Glu Tyr Tyr Asn Ser Leu Lys Trp Ile Leu 
                725                 730                 735     


Glu Asn Asp Pro Thr Glu Leu Asp Leu Met Phe Cys Ile Asp Glu Glu 
            740                 745                 750         


Asn Phe Gly Gln Thr Tyr Gln Val Asp Leu Lys Pro Asn Gly Ser Glu 
        755                 760                 765             


Ile Met Val Thr Asn Glu Asn Lys Arg Glu Tyr Ile Asp Leu Val Ile 
    770                 775                 780                 


Gln Trp Arg Phe Val Asn Arg Val Gln Lys Gln Met Asn Ala Phe Leu 
785                 790                 795                 800 


Glu Gly Phe Thr Glu Leu Leu Pro Ile Asp Leu Ile Lys Ile Phe Asp 
                805                 810                 815     


Glu Asn Glu Leu Glu Leu Leu Met Cys Gly Leu Gly Asp Val Asp Val 
            820                 825                 830         


Asn Asp Trp Arg Gln His Ser Ile Tyr Lys Asn Gly Tyr Cys Pro Asn 
        835                 840                 845             


His Pro Val Ile Gln Trp Phe Trp Lys Ala Val Leu Leu Met Asp Ala 
    850                 855                 860                 


Glu Lys Arg Ile Arg Leu Leu Gln Phe Val Thr Gly Thr Ser Arg Val 
865                 870                 875                 880 


Pro Met Asn Gly Phe Ala Glu Leu Tyr Gly Ser Asn Gly Pro Gln Leu 
                885                 890                 895     


Phe Thr Ile Glu Gln Trp Gly Ser Pro Glu Lys Leu Pro Arg Ala His 
            900                 905                 910         


Thr Cys Phe Asn Arg Leu Asp Leu Pro Pro Tyr Glu Thr Phe Glu Asp 
        915                 920                 925             


Leu Arg Glu Lys Leu Leu Met Ala Val Glu Asn Ala Gln Gly Phe Glu 
    930                 935                 940                 


Gly Val Asp 
945         


<210>  3416
<211>  475
<212>  PRT
<213>  homo sapiens

<400>  3416

Met Ile His Arg His Lys His Glu Met Thr Leu Lys Phe Pro Ser Ile 
1               5                   10                  15      


Lys Thr Asp Asn Met Leu Ser Asp Gln Thr Pro Thr Pro Thr Arg Phe 
            20                  25                  30          


Leu Lys Asn Cys Glu Glu Val Gly Leu Phe Ser Glu Leu Asp Cys Ser 
        35                  40                  45              


Leu Glu His Glu Phe Arg Lys Ala Gln Glu Glu Glu Ser Ser Lys Arg 
    50                  55                  60                  


Asn Ile Ser Met His Asn Ala Val Gly Gly Ala Met Thr Gly Pro Gly 
65                  70                  75                  80  


Thr His Gln Leu Ser Ser Ala Arg Leu Pro Asn His Asp Thr Asn Val 
                85                  90                  95      


Val Ile Gln Gln Ala Met Pro Ser Pro Gln Ser Ser Ser Val Ile Thr 
            100                 105                 110         


Gln Ala Pro Ser Thr Asn Arg Gln Ile Gly Pro Val Pro Gly Ser Leu 
        115                 120                 125             


Ser Ser Leu Leu His Leu His Asn Arg Gln Arg Gln Pro Met Pro Ala 
    130                 135                 140                 


Ser Met Pro Gly Thr Leu Pro Asn Pro Thr Met Pro Gly Ser Ser Ala 
145                 150                 155                 160 


Val Leu Met Pro Met Glu Arg Gln Met Ser Val Asn Ser Ser Ile Met 
                165                 170                 175     


Gly Met Gln Gly Pro Asn Leu Ser Asn Pro Cys Ala Ser Pro Gln Val 
            180                 185                 190         


Gln Pro Met His Ser Glu Ala Lys Met Arg Leu Lys Ala Ala Leu Thr 
        195                 200                 205             


His His Pro Ala Ala Met Ser Asn Gly Asn Met Asn Thr Met Gly His 
    210                 215                 220                 


Met Met Glu Met Met Gly Ser Arg Gln Asp Gln Thr Pro His His His 
225                 230                 235                 240 


Met His Ser His Pro His Gln His Gln Thr Leu Pro Pro His His Pro 
                245                 250                 255     


Tyr Pro His Gln His Gln His Pro Ala His His Pro His Pro Gln Pro 
            260                 265                 270         


His His Gln Gln Asn His Pro His His His Ser His Ser His Leu His 
        275                 280                 285             


Ala His Pro Ala His His Gln Thr Ser Pro His Pro Pro Leu His Thr 
    290                 295                 300                 


Gly Asn Gln Ala Gln Val Ser Pro Ala Thr Gln Gln Met Gln Pro Thr 
305                 310                 315                 320 


Gln Thr Ile Gln Pro Pro Gln Pro Thr Gly Gly Arg Arg Arg Arg Val 
                325                 330                 335     


Val Asp Glu Asp Pro Asp Glu Arg Arg Arg Lys Phe Leu Glu Arg Asn 
            340                 345                 350         


Arg Ala Ala Ala Thr Arg Cys Arg Gln Lys Arg Lys Val Trp Val Met 
        355                 360                 365             


Ser Leu Glu Lys Lys Ala Glu Glu Leu Thr Gln Thr Asn Met Gln Leu 
    370                 375                 380                 


Gln Asn Glu Val Ser Met Leu Lys Asn Glu Val Ala Gln Leu Lys Gln 
385                 390                 395                 400 


Leu Leu Leu Thr His Lys Asp Cys Pro Ile Thr Ala Met Gln Lys Glu 
                405                 410                 415     


Ser Gln Gly Tyr Leu Ser Pro Glu Ser Ser Pro Pro Ala Ser Pro Val 
            420                 425                 430         


Pro Ala Cys Ser Gln Gln Gln Val Ile Gln His Asn Thr Ile Thr Thr 
        435                 440                 445             


Ser Ser Ser Val Ser Glu Val Val Gly Ser Ser Thr Leu Ser Gln Leu 
    450                 455                 460                 


Thr Thr His Arg Thr Asp Leu Asn Pro Ile Leu 
465                 470                 475 


<210>  3417
<211>  276
<212>  PRT
<213>  homo sapiens

<400>  3417

Met Ser Lys Pro Val Asp His Val Lys Arg Pro Met Asn Ala Phe Met 
1               5                   10                  15      


Val Trp Ser Arg Ala Gln Arg Arg Lys Met Ala Gln Glu Asn Pro Lys 
            20                  25                  30          


Met His Asn Ser Glu Ile Ser Lys Arg Leu Gly Ala Glu Trp Lys Leu 
        35                  40                  45              


Leu Thr Glu Ser Glu Lys Arg Pro Phe Ile Asp Glu Ala Lys Arg Leu 
    50                  55                  60                  


Arg Ala Met His Met Lys Glu His Pro Asp Tyr Lys Tyr Arg Pro Arg 
65                  70                  75                  80  


Arg Lys Pro Lys Thr Leu Leu Lys Lys Asp Lys Phe Ala Phe Pro Val 
                85                  90                  95      


Pro Tyr Gly Leu Gly Gly Val Ala Asp Ala Glu His Pro Ala Leu Lys 
            100                 105                 110         


Ala Gly Ala Gly Leu His Ala Gly Ala Gly Gly Gly Leu Val Pro Glu 
        115                 120                 125             


Ser Leu Leu Ala Asn Pro Glu Lys Ala Ala Ala Ala Ala Ala Ala Ala 
    130                 135                 140                 


Ala Ala Arg Val Phe Phe Pro Gln Ser Ala Ala Ala Ala Ala Ala Ala 
145                 150                 155                 160 


Ala Ala Ala Ala Ala Ala Gly Ser Pro Tyr Ser Leu Leu Asp Leu Gly 
                165                 170                 175     


Ser Lys Met Ala Glu Ile Ser Ser Ser Ser Ser Gly Leu Pro Tyr Ala 
            180                 185                 190         


Ser Ser Leu Gly Tyr Pro Thr Ala Gly Ala Gly Ala Phe His Gly Ala 
        195                 200                 205             


Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Gly Gly His Thr His 
    210                 215                 220                 


Ser His Pro Ser Pro Gly Asn Pro Gly Tyr Met Ile Pro Cys Asn Cys 
225                 230                 235                 240 


Ser Ala Trp Pro Ser Pro Gly Leu Gln Pro Pro Leu Ala Tyr Ile Leu 
                245                 250                 255     


Leu Pro Gly Met Gly Lys Pro Gln Leu Asp Pro Tyr Pro Ala Ala Tyr 
            260                 265                 270         


Ala Ala Ala Leu 
        275     


<210>  3418
<211>  474
<212>  PRT
<213>  homo sapiens

<400>  3418

Met Val Gln Gln Thr Asn Asn Ala Glu Asn Thr Glu Ala Leu Leu Ala 
1               5                   10                  15      


Gly Glu Ser Ser Asp Ser Gly Ala Gly Leu Glu Leu Gly Ile Ala Ser 
            20                  25                  30          


Ser Pro Thr Pro Gly Ser Thr Ala Ser Thr Gly Gly Lys Ala Asp Asp 
        35                  40                  45              


Pro Ser Trp Cys Lys Thr Pro Ser Gly His Ile Lys Arg Pro Met Asn 
    50                  55                  60                  


Ala Phe Met Val Trp Ser Gln Ile Glu Arg Arg Lys Ile Met Glu Gln 
65                  70                  75                  80  


Ser Pro Asp Met His Asn Ala Glu Ile Ser Lys Arg Leu Gly Lys Arg 
                85                  90                  95      


Trp Lys Leu Leu Lys Asp Ser Asp Lys Ile Pro Phe Ile Arg Glu Ala 
            100                 105                 110         


Glu Arg Leu Arg Leu Lys His Met Ala Asp Tyr Pro Asp Tyr Lys Tyr 
        115                 120                 125             


Arg Pro Arg Lys Lys Val Lys Ser Gly Asn Ala Asn Ser Ser Ser Ser 
    130                 135                 140                 


Ala Ala Ala Ser Ser Lys Pro Gly Glu Lys Gly Asp Lys Val Gly Gly 
145                 150                 155                 160 


Ser Gly Gly Gly Gly His Gly Gly Gly Gly Gly Gly Gly Ser Ser Asn 
                165                 170                 175     


Ala Gly Gly Gly Gly Gly Gly Ala Ser Gly Gly Gly Ala Asn Ser Lys 
            180                 185                 190         


Pro Ala Gln Lys Lys Ser Cys Gly Ser Lys Val Ala Gly Gly Ala Gly 
        195                 200                 205             


Gly Gly Val Ser Lys Pro His Ala Lys Leu Ile Leu Ala Gly Gly Gly 
    210                 215                 220                 


Gly Gly Gly Lys Ala Ala Ala Ala Ala Ala Ala Ser Phe Ala Ala Glu 
225                 230                 235                 240 


Gln Ala Gly Ala Ala Ala Leu Leu Pro Leu Gly Ala Ala Ala Asp His 
                245                 250                 255     


His Ser Leu Tyr Lys Ala Arg Thr Pro Ser Ala Ser Ala Ser Ala Ser 
            260                 265                 270         


Ser Ala Ala Ser Ala Ser Ala Ala Leu Ala Ala Pro Gly Lys His Leu 
        275                 280                 285             


Ala Glu Lys Lys Val Lys Arg Val Tyr Leu Phe Gly Gly Leu Gly Thr 
    290                 295                 300                 


Ser Ser Ser Pro Val Gly Gly Val Gly Ala Gly Ala Asp Pro Ser Asp 
305                 310                 315                 320 


Pro Leu Gly Leu Tyr Glu Glu Glu Gly Ala Gly Cys Ser Pro Asp Ala 
                325                 330                 335     


Pro Ser Leu Ser Gly Arg Ser Ser Ala Ala Ser Ser Pro Ala Ala Gly 
            340                 345                 350         


Arg Ser Pro Ala Asp His Arg Gly Tyr Ala Ser Leu Arg Ala Ala Ser 
        355                 360                 365             


Pro Ala Pro Ser Ser Ala Pro Ser His Ala Ser Ser Ser Ala Ser Ser 
    370                 375                 380                 


His Ser Ser Ser Ser Ser Ser Ser Gly Ser Ser Ser Ser Asp Asp Glu 
385                 390                 395                 400 


Phe Glu Asp Asp Leu Leu Asp Leu Asn Pro Ser Ser Asn Phe Glu Ser 
                405                 410                 415     


Met Ser Leu Gly Ser Phe Ser Ser Ser Ser Ala Leu Asp Arg Asp Leu 
            420                 425                 430         


Asp Phe Asn Phe Glu Pro Gly Ser Gly Ser His Phe Glu Phe Pro Asp 
        435                 440                 445             


Tyr Cys Thr Pro Glu Val Ser Glu Met Ile Ser Gly Asp Trp Leu Glu 
    450                 455                 460                 


Ser Ser Ile Ser Asn Leu Val Phe Thr Tyr 
465                 470                 


<210>  3419
<211>  311
<212>  PRT
<213>  homo sapiens

<400>  3419

Met Thr Gly Ser Ala Ala Asp Thr His Arg Cys Pro His Pro Lys Gly 
1               5                   10                  15      


Ala Lys Gly Thr Arg Ser Arg Ser Ser His Ala Arg Pro Val Ser Leu 
            20                  25                  30          


Ala Thr Ser Gly Gly Ser Glu Glu Glu Asp Lys Asp Gly Gly Val Leu 
        35                  40                  45              


Phe His Val Asn Lys Ser Gly Phe Pro Ile Asp Ser His Thr Trp Glu 
    50                  55                  60                  


Arg Met Trp Met His Val Ala Lys Val His Pro Lys Gly Gly Glu Met 
65                  70                  75                  80  


Val Gly Ala Ile Arg Asn Ala Ala Phe Leu Ala Lys Pro Ser Ile Pro 
                85                  90                  95      


Gln Val Pro Asn Tyr Arg Leu Ser Met Thr Ile Pro Asp Trp Leu Gln 
            100                 105                 110         


Ala Ile Gln Asn Tyr Met Lys Thr Leu His Tyr Leu Thr Asn Gly Gln 
        115                 120                 125             


Pro Ser Ile Glu Arg Phe Pro Ile Ser Phe Lys Thr Tyr Phe Ser Gly 
    130                 135                 140                 


Asn Tyr Phe His His Val Val Leu Gly Ile Tyr Cys Asn Gly Arg Tyr 
145                 150                 155                 160 


Gly Ser Leu Gly Met Ser Arg Arg Ala Glu Leu Met Asp Lys Pro Leu 
                165                 170                 175     


Thr Phe Arg Thr Leu Ser Asp Leu Ile Phe Asp Phe Glu Asp Ser Tyr 
            180                 185                 190         


Lys Lys Tyr Leu His Thr Val Lys Lys Val Lys Ile Gly Leu Tyr Val 
        195                 200                 205             


Pro His Glu Pro His Ser Phe Gln Pro Ile Glu Trp Lys Gln Leu Val 
    210                 215                 220                 


Leu Asn Val Ser Lys Met Leu Arg Ala Asp Ile Arg Lys Glu Leu Glu 
225                 230                 235                 240 


Lys Tyr Ala Arg Asp Met Arg Met Lys Ile Leu Lys Pro Ala Ser Ala 
                245                 250                 255     


His Ser Pro Thr Gln Val Arg Ser Arg Gly Lys Ser Leu Ser Pro Arg 
            260                 265                 270         


Arg Arg Gln Ala Ser Pro Pro Arg Arg Leu Gly Arg Arg Glu Lys Ser 
        275                 280                 285             


Pro Ala Leu Pro Glu Lys Lys Val Ala Asp Leu Ser Thr Leu Asn Glu 
    290                 295                 300                 


Val Gly Tyr Gln Ile Arg Ile 
305                 310     


<210>  3420
<211>  194
<212>  PRT
<213>  homo sapiens

<400>  3420

Met Thr Glu Asn Ser Thr Ser Ala Pro Ala Ala Lys Pro Lys Arg Ala 
1               5                   10                  15      


Lys Ala Ser Lys Lys Ser Thr Asp His Pro Lys Tyr Ser Asp Met Ile 
            20                  25                  30          


Val Ala Ala Ile Gln Ala Glu Lys Asn Arg Ala Gly Ser Ser Arg Gln 
        35                  40                  45              


Ser Ile Gln Lys Tyr Ile Lys Ser His Tyr Lys Val Gly Glu Asn Ala 
    50                  55                  60                  


Asp Ser Gln Ile Lys Leu Ser Ile Lys Arg Leu Val Thr Thr Gly Val 
65                  70                  75                  80  


Leu Lys Gln Thr Lys Gly Val Gly Ala Ser Gly Ser Phe Arg Leu Ala 
                85                  90                  95      


Lys Ser Asp Glu Pro Lys Lys Ser Val Ala Phe Lys Lys Thr Lys Lys 
            100                 105                 110         


Glu Ile Lys Lys Val Ala Thr Pro Lys Lys Ala Ser Lys Pro Lys Lys 
        115                 120                 125             


Ala Ala Ser Lys Ala Pro Thr Lys Lys Pro Lys Ala Thr Pro Val Lys 
    130                 135                 140                 


Lys Ala Lys Lys Lys Leu Ala Ala Thr Pro Lys Lys Ala Lys Lys Pro 
145                 150                 155                 160 


Lys Thr Val Lys Ala Lys Pro Val Lys Ala Ser Lys Pro Lys Lys Ala 
                165                 170                 175     


Lys Pro Val Lys Pro Lys Ala Lys Ser Ser Ala Lys Arg Ala Gly Lys 
            180                 185                 190         


Lys Lys 
        


<210>  3421
<211>  666
<212>  PRT
<213>  homo sapiens

<400>  3421

Met Glu Gln Glu Pro Gln Asn Gly Glu Pro Ala Glu Ile Lys Ile Ile 
1               5                   10                  15      


Arg Glu Ala Tyr Lys Lys Ala Phe Leu Phe Val Asn Lys Gly Leu Asn 
            20                  25                  30          


Thr Asp Glu Leu Gly Gln Lys Glu Glu Ala Lys Asn Tyr Tyr Lys Gln 
        35                  40                  45              


Gly Ile Gly His Leu Leu Arg Gly Ile Ser Ile Ser Ser Lys Glu Ser 
    50                  55                  60                  


Glu His Thr Gly Pro Gly Trp Glu Ser Ala Arg Gln Met Gln Gln Lys 
65                  70                  75                  80  


Met Lys Glu Thr Leu Gln Asn Val Arg Thr Arg Leu Glu Ile Leu Glu 
                85                  90                  95      


Lys Gly Leu Ala Thr Ser Leu Gln Asn Asp Leu Gln Glu Val Pro Lys 
            100                 105                 110         


Leu Tyr Pro Glu Phe Pro Pro Lys Asp Met Cys Glu Lys Leu Pro Glu 
        115                 120                 125             


Pro Gln Ser Phe Ser Ser Ala Pro Gln His Ala Glu Val Asn Gly Asn 
    130                 135                 140                 


Thr Ser Thr Pro Ser Ala Gly Ala Val Ala Ala Pro Ala Ser Leu Ser 
145                 150                 155                 160 


Leu Pro Ser Gln Ser Cys Pro Ala Glu Ala Pro Pro Ala Tyr Thr Pro 
                165                 170                 175     


Gln Ala Ala Glu Gly His Tyr Thr Val Ser Tyr Gly Thr Asp Ser Gly 
            180                 185                 190         


Glu Phe Ser Ser Val Gly Glu Glu Phe Tyr Arg Asn His Ser Gln Pro 
        195                 200                 205             


Pro Pro Leu Glu Thr Leu Gly Leu Asp Ala Asp Glu Leu Ile Leu Ile 
    210                 215                 220                 


Pro Asn Gly Val Gln Ile Phe Phe Val Asn Pro Ala Gly Glu Val Ser 
225                 230                 235                 240 


Ala Pro Ser Tyr Pro Gly Tyr Leu Arg Ile Val Arg Phe Leu Asp Asn 
                245                 250                 255     


Ser Leu Asp Thr Val Leu Asn Arg Pro Pro Gly Phe Leu Gln Val Cys 
            260                 265                 270         


Asp Trp Leu Tyr Pro Leu Val Pro Asp Arg Ser Pro Val Leu Lys Cys 
        275                 280                 285             


Thr Ala Gly Ala Tyr Met Phe Pro Asp Thr Met Leu Gln Ala Ala Gly 
    290                 295                 300                 


Cys Phe Val Gly Val Val Leu Ser Ser Glu Leu Pro Glu Asp Asp Arg 
305                 310                 315                 320 


Glu Leu Phe Glu Asp Leu Leu Arg Gln Met Ser Asp Leu Arg Leu Gln 
                325                 330                 335     


Ala Asn Trp Asn Arg Ala Glu Glu Glu Asn Glu Phe Gln Ile Pro Gly 
            340                 345                 350         


Arg Thr Arg Pro Ser Ser Asp Gln Leu Lys Glu Ala Ser Gly Thr Asp 
        355                 360                 365             


Val Lys Gln Leu Asp Gln Gly Asn Lys Asp Val Arg His Lys Gly Lys 
    370                 375                 380                 


Arg Gly Lys Arg Ala Lys Asp Thr Ser Ser Glu Glu Val Asn Leu Ser 
385                 390                 395                 400 


His Ile Val Pro Cys Glu Pro Val Pro Glu Glu Lys Pro Lys Glu Leu 
                405                 410                 415     


Pro Glu Trp Ser Glu Lys Val Ala His Asn Ile Leu Ser Gly Ala Ser 
            420                 425                 430         


Trp Val Ser Trp Gly Leu Val Lys Gly Ala Glu Ile Thr Gly Lys Ala 
        435                 440                 445             


Ile Gln Lys Gly Ala Ser Lys Leu Arg Glu Arg Ile Gln Pro Glu Glu 
    450                 455                 460                 


Lys Pro Val Glu Val Ser Pro Ala Val Thr Lys Gly Leu Tyr Ile Ala 
465                 470                 475                 480 


Lys Gln Ala Thr Gly Gly Ala Ala Lys Val Ser Gln Phe Leu Val Asp 
                485                 490                 495     


Gly Val Cys Thr Val Ala Asn Cys Val Gly Lys Glu Leu Ala Pro His 
            500                 505                 510         


Val Lys Lys His Gly Ser Lys Leu Val Pro Glu Ser Leu Lys Lys Asp 
        515                 520                 525             


Lys Asp Gly Lys Ser Pro Leu Asp Gly Ala Met Val Val Ala Ala Ser 
    530                 535                 540                 


Ser Val Gln Gly Phe Ser Thr Val Trp Gln Gly Leu Glu Cys Ala Ala 
545                 550                 555                 560 


Lys Cys Ile Val Asn Asn Val Ser Ala Glu Thr Val Gln Thr Val Arg 
                565                 570                 575     


Tyr Lys Tyr Gly Tyr Asn Ala Gly Glu Ala Thr His His Ala Val Asp 
            580                 585                 590         


Ser Ala Val Asn Val Gly Val Thr Ala Tyr Asn Ile Asn Asn Ile Gly 
        595                 600                 605             


Ile Lys Ala Met Val Lys Lys Thr Ala Thr Gln Thr Gly His Thr Leu 
    610                 615                 620                 


Leu Glu Asp Tyr Gln Ile Val Asp Asn Ser Gln Arg Glu Asn Gln Glu 
625                 630                 635                 640 


Gly Ala Ala Asn Val Asn Val Arg Gly Glu Lys Asp Glu Gln Thr Lys 
                645                 650                 655     


Glu Val Lys Glu Ala Lys Lys Lys Asp Lys 
            660                 665     


<210>  3422
<211>  967
<212>  PRT
<213>  homo sapiens

<400>  3422

Met Arg Arg Leu Ala Phe Glu Gln Gly Glu Ser Arg Ile Leu Arg Val 
1               5                   10                  15      


Lys Val Val Ser Gly Ile Asp Leu Ala Lys Lys Asp Ile Phe Gly Ala 
            20                  25                  30          


Ser Asp Pro Tyr Val Lys Leu Ser Leu Tyr Val Ala Asp Glu Asn Arg 
        35                  40                  45              


Glu Leu Ala Leu Val Gln Thr Lys Thr Ile Lys Lys Thr Leu Asn Pro 
    50                  55                  60                  


Lys Trp Asn Glu Glu Phe Tyr Phe Arg Val Asn Pro Ser Asn His Arg 
65                  70                  75                  80  


Leu Leu Phe Glu Val Phe Asp Glu Asn Arg Leu Thr Arg Asp Asp Phe 
                85                  90                  95      


Leu Gly Gln Val Asp Val Pro Leu Ser His Leu Pro Thr Glu Asp Pro 
            100                 105                 110         


Thr Met Glu Arg Pro Tyr Thr Phe Lys Asp Phe Leu Leu Arg Pro Arg 
        115                 120                 125             


Ser His Lys Ser Arg Val Lys Gly Phe Leu Arg Leu Lys Met Ala Tyr 
    130                 135                 140                 


Met Pro Lys Asn Gly Gly Gln Asp Glu Glu Asn Ser Asp Gln Arg Asp 
145                 150                 155                 160 


Asp Met Glu His Gly Trp Glu Val Val Asp Ser Asn Asp Ser Ala Ser 
                165                 170                 175     


Gln His Gln Glu Glu Leu Pro Pro Pro Pro Leu Pro Pro Gly Trp Glu 
            180                 185                 190         


Glu Lys Val Asp Asn Leu Gly Arg Thr Tyr Tyr Val Asn His Asn Asn 
        195                 200                 205             


Arg Thr Thr Gln Trp His Arg Pro Ser Leu Met Asp Val Ser Ser Glu 
    210                 215                 220                 


Ser Asp Asn Asn Ile Arg Gln Ile Asn Gln Glu Ala Ala His Arg Arg 
225                 230                 235                 240 


Phe Arg Ser Arg Arg His Ile Ser Glu Asp Leu Glu Pro Glu Pro Ser 
                245                 250                 255     


Glu Gly Gly Asp Val Pro Glu Pro Trp Glu Thr Ile Ser Glu Glu Val 
            260                 265                 270         


Asn Ile Ala Gly Asp Ser Leu Gly Leu Ala Leu Pro Pro Pro Pro Ala 
        275                 280                 285             


Ser Pro Gly Ser Arg Thr Ser Pro Gln Glu Leu Ser Glu Glu Leu Ser 
    290                 295                 300                 


Arg Arg Leu Gln Ile Thr Pro Asp Ser Asn Gly Glu Gln Phe Ser Ser 
305                 310                 315                 320 


Leu Ile Gln Arg Glu Pro Ser Ser Arg Leu Arg Ser Cys Ser Val Thr 
                325                 330                 335     


Asp Ala Val Ala Glu Gln Gly His Leu Pro Pro Pro Ser Ala Pro Ala 
            340                 345                 350         


Gly Arg Ala Arg Ser Ser Thr Val Thr Gly Gly Glu Glu Pro Thr Pro 
        355                 360                 365             


Ser Val Ala Tyr Val His Thr Thr Pro Gly Leu Pro Ser Gly Trp Glu 
    370                 375                 380                 


Glu Arg Lys Asp Ala Lys Gly Arg Thr Tyr Tyr Val Asn His Asn Asn 
385                 390                 395                 400 


Arg Thr Thr Thr Trp Thr Arg Pro Ile Met Gln Leu Ala Glu Asp Gly 
                405                 410                 415     


Ala Ser Gly Ser Ala Thr Asn Ser Asn Asn His Leu Ile Glu Pro Gln 
            420                 425                 430         


Ile Arg Arg Pro Arg Ser Leu Ser Ser Pro Thr Val Thr Leu Ser Ala 
        435                 440                 445             


Pro Leu Glu Gly Ala Lys Asp Ser Pro Val Arg Arg Ala Val Lys Asp 
    450                 455                 460                 


Thr Leu Ser Asn Pro Gln Ser Pro Gln Pro Ser Pro Tyr Asn Ser Pro 
465                 470                 475                 480 


Lys Pro Gln His Lys Val Thr Gln Ser Phe Leu Pro Pro Gly Trp Glu 
                485                 490                 495     


Met Arg Ile Ala Pro Asn Gly Arg Pro Phe Phe Ile Asp His Asn Thr 
            500                 505                 510         


Lys Thr Thr Thr Trp Glu Asp Pro Arg Leu Lys Phe Pro Val His Met 
        515                 520                 525             


Arg Ser Lys Thr Ser Leu Asn Pro Asn Asp Leu Gly Pro Leu Pro Pro 
    530                 535                 540                 


Gly Trp Glu Glu Arg Ile His Leu Asp Gly Arg Thr Phe Tyr Ile Asp 
545                 550                 555                 560 


His Asn Ser Lys Ile Thr Gln Trp Glu Asp Pro Arg Leu Gln Asn Pro 
                565                 570                 575     


Ala Ile Thr Gly Pro Ala Val Pro Tyr Ser Arg Glu Phe Lys Gln Lys 
            580                 585                 590         


Tyr Asp Tyr Phe Arg Lys Lys Leu Lys Lys Pro Ala Asp Ile Pro Asn 
        595                 600                 605             


Arg Phe Glu Met Lys Leu His Arg Asn Asn Ile Phe Glu Glu Ser Tyr 
    610                 615                 620                 


Arg Arg Ile Met Ser Val Lys Arg Pro Asp Val Leu Lys Ala Arg Leu 
625                 630                 635                 640 


Trp Ile Glu Phe Glu Ser Glu Lys Gly Leu Asp Tyr Gly Gly Val Ala 
                645                 650                 655     


Arg Glu Trp Phe Phe Leu Leu Ser Lys Glu Met Phe Asn Pro Tyr Tyr 
            660                 665                 670         


Gly Leu Phe Glu Tyr Ser Ala Thr Asp Asn Tyr Thr Leu Gln Ile Asn 
        675                 680                 685             


Pro Asn Ser Gly Leu Cys Asn Glu Asp His Leu Ser Tyr Phe Thr Phe 
    690                 695                 700                 


Ile Gly Arg Val Ala Gly Leu Ala Val Phe His Gly Lys Leu Leu Asp 
705                 710                 715                 720 


Gly Phe Phe Ile Arg Pro Phe Tyr Lys Met Met Leu Gly Lys Gln Ile 
                725                 730                 735     


Thr Leu Asn Asp Met Glu Ser Val Asp Ser Glu Tyr Tyr Asn Ser Leu 
            740                 745                 750         


Lys Trp Ile Leu Glu Asn Asp Pro Thr Glu Leu Asp Leu Met Phe Cys 
        755                 760                 765             


Ile Asp Glu Glu Asn Phe Gly Gln Thr Tyr Gln Val Asp Leu Lys Pro 
    770                 775                 780                 


Asn Gly Ser Glu Ile Met Val Thr Asn Glu Asn Lys Arg Glu Tyr Ile 
785                 790                 795                 800 


Asp Leu Val Ile Gln Trp Arg Phe Val Asn Arg Val Gln Lys Gln Met 
                805                 810                 815     


Asn Ala Phe Leu Glu Gly Phe Thr Glu Leu Leu Pro Ile Asp Leu Ile 
            820                 825                 830         


Lys Ile Phe Asp Glu Asn Glu Leu Glu Leu Leu Met Cys Gly Leu Gly 
        835                 840                 845             


Asp Val Asp Val Asn Asp Trp Arg Gln His Ser Ile Tyr Lys Asn Gly 
    850                 855                 860                 


Tyr Cys Pro Asn His Pro Val Ile Gln Trp Phe Trp Lys Ala Val Leu 
865                 870                 875                 880 


Leu Met Asp Ala Glu Lys Arg Ile Arg Leu Leu Gln Phe Val Thr Gly 
                885                 890                 895     


Thr Ser Arg Val Pro Met Asn Gly Phe Ala Glu Leu Tyr Gly Ser Asn 
            900                 905                 910         


Gly Pro Gln Leu Phe Thr Ile Glu Gln Trp Gly Ser Pro Glu Lys Leu 
        915                 920                 925             


Pro Arg Ala His Thr Cys Phe Asn Arg Leu Asp Leu Pro Pro Tyr Glu 
    930                 935                 940                 


Thr Phe Glu Asp Leu Arg Glu Lys Leu Leu Met Ala Val Glu Asn Ala 
945                 950                 955                 960 


Gln Gly Phe Glu Gly Val Asp 
                965         


<210>  3423
<211>  206
<212>  PRT
<213>  homo sapiens

<400>  3423

Met Thr Thr Leu Ala Gly Ala Val Pro Arg Met Met Arg Pro Gly Pro 
1               5                   10                  15      


Gly Gln Asn Tyr Pro Arg Ser Gly Phe Pro Leu Glu Val Ser Thr Pro 
            20                  25                  30          


Leu Gly Gln Gly Arg Val Asn Gln Leu Gly Gly Val Phe Ile Asn Gly 
        35                  40                  45              


Arg Pro Leu Pro Asn His Ile Arg His Lys Ile Val Glu Met Ala His 
    50                  55                  60                  


His Gly Ile Arg Pro Cys Val Ile Ser Arg Gln Leu Arg Val Ser His 
65                  70                  75                  80  


Gly Cys Val Ser Lys Ile Leu Cys Arg Tyr Gln Glu Thr Gly Ser Ile 
                85                  90                  95      


Arg Pro Gly Ala Ile Gly Gly Ser Lys Pro Lys Gln Val Thr Thr Pro 
            100                 105                 110         


Asp Val Glu Lys Lys Ile Glu Glu Tyr Lys Arg Glu Asn Pro Gly Met 
        115                 120                 125             


Phe Ser Trp Glu Ile Arg Asp Lys Leu Leu Lys Asp Ala Val Cys Asp 
    130                 135                 140                 


Arg Asn Thr Val Pro Ser Val Ser Ser Ile Ser Arg Ile Leu Arg Ser 
145                 150                 155                 160 


Lys Phe Gly Lys Gly Glu Glu Glu Glu Ala Asp Leu Glu Arg Lys Glu 
                165                 170                 175     


Ala Glu Glu Ser Glu Lys Lys Ala Lys His Ser Ile Asp Gly Ile Leu 
            180                 185                 190         


Ser Glu Arg Gly Lys Ala Leu Val Ser Gly Val Ser Ser His 
        195                 200                 205     


<210>  3424
<211>  479
<212>  PRT
<213>  homo sapiens

<400>  3424

Met Thr Thr Leu Ala Gly Ala Val Pro Arg Met Met Arg Pro Gly Pro 
1               5                   10                  15      


Gly Gln Asn Tyr Pro Arg Ser Gly Phe Pro Leu Glu Val Ser Thr Pro 
            20                  25                  30          


Leu Gly Gln Gly Arg Val Asn Gln Leu Gly Gly Val Phe Ile Asn Gly 
        35                  40                  45              


Arg Pro Leu Pro Asn His Ile Arg His Lys Ile Val Glu Met Ala His 
    50                  55                  60                  


His Gly Ile Arg Pro Cys Val Ile Ser Arg Gln Leu Arg Val Ser His 
65                  70                  75                  80  


Gly Cys Val Ser Lys Ile Leu Cys Arg Tyr Gln Glu Thr Gly Ser Ile 
                85                  90                  95      


Arg Pro Gly Ala Ile Gly Gly Ser Lys Pro Lys Gln Val Thr Thr Pro 
            100                 105                 110         


Asp Val Glu Lys Lys Ile Glu Glu Tyr Lys Arg Glu Asn Pro Gly Met 
        115                 120                 125             


Phe Ser Trp Glu Ile Arg Asp Lys Leu Leu Lys Asp Ala Val Cys Asp 
    130                 135                 140                 


Arg Asn Thr Val Pro Ser Val Ser Ser Ile Ser Arg Ile Leu Arg Ser 
145                 150                 155                 160 


Lys Phe Gly Lys Gly Glu Glu Glu Glu Ala Asp Leu Glu Arg Lys Glu 
                165                 170                 175     


Ala Glu Glu Ser Glu Lys Lys Ala Lys His Ser Ile Asp Gly Ile Leu 
            180                 185                 190         


Ser Glu Arg Ala Ser Ala Pro Gln Ser Asp Glu Gly Ser Asp Ile Asp 
        195                 200                 205             


Ser Glu Pro Asp Leu Pro Leu Lys Arg Lys Gln Arg Arg Ser Arg Thr 
    210                 215                 220                 


Thr Phe Thr Ala Glu Gln Leu Glu Glu Leu Glu Arg Ala Phe Glu Arg 
225                 230                 235                 240 


Thr His Tyr Pro Asp Ile Tyr Thr Arg Glu Glu Leu Ala Gln Arg Ala 
                245                 250                 255     


Lys Leu Thr Glu Ala Arg Val Gln Val Trp Phe Ser Asn Arg Arg Ala 
            260                 265                 270         


Arg Trp Arg Lys Gln Ala Gly Ala Asn Gln Leu Met Ala Phe Asn His 
        275                 280                 285             


Leu Ile Pro Gly Gly Phe Pro Pro Thr Ala Met Pro Thr Leu Pro Thr 
    290                 295                 300                 


Tyr Gln Leu Ser Glu Thr Ser Tyr Gln Pro Thr Ser Ile Pro Gln Ala 
305                 310                 315                 320 


Val Ser Asp Pro Ser Ser Thr Val His Arg Pro Gln Pro Leu Pro Pro 
                325                 330                 335     


Ser Thr Val His Gln Ser Thr Ile Pro Ser Asn Pro Asp Ser Ser Ser 
            340                 345                 350         


Ala Tyr Cys Leu Pro Ser Thr Arg His Gly Phe Ser Ser Tyr Thr Asp 
        355                 360                 365             


Ser Phe Val Pro Pro Ser Gly Pro Ser Asn Pro Met Asn Pro Thr Ile 
    370                 375                 380                 


Gly Asn Gly Leu Ser Pro Gln Val Met Gly Leu Leu Thr Asn His Gly 
385                 390                 395                 400 


Gly Val Pro His Gln Pro Gln Thr Asp Tyr Ala Leu Ser Pro Leu Thr 
                405                 410                 415     


Gly Gly Leu Glu Pro Thr Thr Thr Val Ser Ala Ser Cys Ser Gln Arg 
            420                 425                 430         


Leu Asp His Met Lys Ser Leu Asp Ser Leu Pro Thr Ser Gln Ser Tyr 
        435                 440                 445             


Cys Pro Pro Thr Tyr Ser Thr Thr Gly Tyr Ser Met Asp Pro Val Thr 
    450                 455                 460                 


Gly Tyr Gln Tyr Gly Gln Tyr Gly Gln Ser Lys Pro Trp Thr Phe 
465                 470                 475                 


<210>  3425
<211>  396
<212>  PRT
<213>  homo sapiens

<400>  3425

Met Pro Arg Val Lys Ala Ala Gln Ala Gly Arg Gln Ser Ser Ala Lys 
1               5                   10                  15      


Arg His Leu Ala Glu Gln Phe Ala Val Gly Glu Ile Ile Thr Asp Met 
            20                  25                  30          


Ala Lys Lys Glu Trp Lys Val Gly Leu Pro Ile Gly Gln Gly Gly Phe 
        35                  40                  45              


Gly Cys Ile Tyr Leu Ala Asp Met Asn Ser Ser Glu Ser Val Gly Ser 
    50                  55                  60                  


Asp Ala Pro Cys Val Val Lys Val Glu Pro Ser Asp Asn Gly Pro Leu 
65                  70                  75                  80  


Phe Thr Glu Leu Lys Phe Tyr Gln Arg Ala Ala Lys Pro Glu Gln Ile 
                85                  90                  95      


Gln Lys Trp Ile Arg Thr Arg Lys Leu Lys Tyr Leu Gly Val Pro Lys 
            100                 105                 110         


Tyr Trp Gly Ser Gly Leu His Asp Lys Asn Gly Lys Ser Tyr Arg Phe 
        115                 120                 125             


Met Ile Met Asp Arg Phe Gly Ser Asp Leu Gln Lys Ile Tyr Glu Ala 
    130                 135                 140                 


Asn Ala Lys Arg Phe Ser Arg Lys Thr Val Leu Gln Leu Ser Leu Arg 
145                 150                 155                 160 


Ile Leu Asp Ile Leu Glu Tyr Ile His Glu His Glu Tyr Val His Gly 
                165                 170                 175     


Asp Ile Lys Ala Ser Asn Leu Leu Leu Asn Tyr Lys Asn Pro Asp Gln 
            180                 185                 190         


Val Tyr Leu Val Asp Tyr Gly Leu Ala Tyr Arg Tyr Cys Pro Glu Gly 
        195                 200                 205             


Val His Lys Glu Tyr Lys Glu Asp Pro Lys Arg Cys His Asp Gly Thr 
    210                 215                 220                 


Ile Glu Phe Thr Ser Ile Asp Ala His Asn Gly Val Ala Pro Ser Arg 
225                 230                 235                 240 


Arg Gly Asp Leu Glu Ile Leu Gly Tyr Cys Met Ile Gln Trp Leu Thr 
                245                 250                 255     


Gly His Leu Pro Trp Glu Asp Asn Leu Lys Asp Pro Lys Tyr Val Arg 
            260                 265                 270         


Asp Ser Lys Ile Arg Tyr Arg Glu Asn Ile Ala Ser Leu Met Asp Lys 
        275                 280                 285             


Cys Phe Pro Glu Lys Asn Lys Pro Gly Glu Ile Ala Lys Tyr Met Glu 
    290                 295                 300                 


Thr Val Lys Leu Leu Asp Tyr Thr Glu Lys Pro Leu Tyr Glu Asn Leu 
305                 310                 315                 320 


Arg Asp Ile Leu Leu Gln Gly Leu Lys Ala Ile Gly Ser Lys Asp Asp 
                325                 330                 335     


Gly Lys Leu Asp Leu Ser Val Val Glu Asn Gly Gly Leu Lys Ala Lys 
            340                 345                 350         


Thr Ile Thr Lys Lys Arg Lys Lys Glu Ile Glu Glu Ser Lys Glu Pro 
        355                 360                 365             


Gly Val Glu Asp Thr Glu Trp Ser Asn Thr Gln Thr Glu Glu Ala Ile 
    370                 375                 380                 


Gln Thr Arg Ser Arg Thr Arg Lys Arg Val Gln Lys 
385                 390                 395     


<210>  3426
<211>  516
<212>  PRT
<213>  homo sapiens

<400>  3426

Met Gly Asp Pro Ser Lys Gln Asp Ile Leu Thr Ile Phe Lys Arg Leu 
1               5                   10                  15      


Arg Ser Val Pro Thr Asn Lys Val Cys Phe Asp Cys Gly Ala Lys Asn 
            20                  25                  30          


Pro Ser Trp Ala Ser Ile Thr Tyr Gly Val Phe Leu Cys Ile Asp Cys 
        35                  40                  45              


Ser Gly Ser His Arg Ser Leu Gly Val His Leu Ser Phe Ile Arg Ser 
    50                  55                  60                  


Thr Glu Leu Asp Ser Asn Trp Ser Trp Phe Gln Leu Arg Cys Met Gln 
65                  70                  75                  80  


Val Gly Gly Asn Ala Ser Ala Ser Ser Phe Phe His Gln His Gly Cys 
                85                  90                  95      


Ser Thr Asn Asp Thr Asn Ala Lys Tyr Asn Ser Arg Ala Ala Gln Leu 
            100                 105                 110         


Tyr Arg Glu Lys Ile Lys Ser Leu Ala Ser Gln Ala Thr Arg Lys His 
        115                 120                 125             


Gly Thr Asp Leu Trp Leu Asp Ser Cys Val Val Pro Pro Leu Ser Pro 
    130                 135                 140                 


Pro Pro Lys Glu Glu Asp Phe Phe Ala Ser His Val Ser Pro Glu Val 
145                 150                 155                 160 


Ser Asp Thr Ala Trp Ala Ser Ala Ile Ala Glu Pro Ser Ser Leu Thr 
                165                 170                 175     


Ser Arg Pro Val Glu Thr Thr Leu Glu Asn Asn Glu Gly Gly Gln Glu 
            180                 185                 190         


Gln Gly Pro Ser Val Glu Gly Leu Asn Val Pro Thr Lys Ala Thr Leu 
        195                 200                 205             


Glu Val Ser Ser Ile Ile Lys Lys Lys Pro Asn Gln Ala Lys Lys Gly 
    210                 215                 220                 


Leu Gly Ala Lys Lys Gly Ser Leu Gly Ala Gln Lys Leu Ala Asn Thr 
225                 230                 235                 240 


Cys Phe Asn Glu Ile Glu Lys Gln Ala Gln Ala Ala Asp Lys Met Lys 
                245                 250                 255     


Glu Gln Glu Asp Leu Ala Lys Val Val Ser Lys Glu Glu Ser Ile Val 
            260                 265                 270         


Ser Ser Leu Arg Leu Ala Tyr Lys Asp Leu Glu Ile Gln Met Lys Lys 
        275                 280                 285             


Asp Glu Lys Met Asn Ile Ser Gly Lys Lys Asn Val Asp Ser Asp Arg 
    290                 295                 300                 


Leu Gly Met Gly Phe Gly Asn Cys Arg Ser Val Ile Ser His Ser Val 
305                 310                 315                 320 


Thr Ser Asp Met Gln Thr Ile Glu Gln Glu Ser Pro Ile Met Ala Lys 
                325                 330                 335     


Pro Arg Lys Lys Tyr Asn Asp Asp Ser Asp Asp Ser Tyr Phe Thr Ser 
            340                 345                 350         


Ser Ser Ser Tyr Phe Asp Glu Pro Val Glu Leu Arg Ser Ser Ser Phe 
        355                 360                 365             


Ser Ser Trp Asp Asp Ser Ser Asp Ser Tyr Trp Lys Lys Glu Thr Ser 
    370                 375                 380                 


Lys Asp Thr Glu Thr Val Leu Lys Thr Thr Gly Tyr Ser Asp Arg Pro 
385                 390                 395                 400 


Thr Ala Arg Arg Lys Pro Asp Tyr Glu Pro Val Glu Asn Thr Asp Glu 
                405                 410                 415     


Ala Gln Lys Lys Phe Gly Asn Val Lys Ala Ile Ser Ser Asp Met Tyr 
            420                 425                 430         


Phe Gly Arg Gln Ser Gln Ala Asp Tyr Glu Thr Arg Ala Arg Leu Glu 
        435                 440                 445             


Arg Leu Ser Ala Ser Ser Ser Ile Ser Ser Ala Asp Leu Phe Glu Glu 
    450                 455                 460                 


Pro Arg Lys Gln Pro Ala Gly Asn Tyr Ser Leu Ser Ser Val Leu Pro 
465                 470                 475                 480 


Asn Ala Pro Asp Met Ala Gln Phe Lys Gln Gly Val Arg Ser Val Ala 
                485                 490                 495     


Gly Lys Leu Ser Val Phe Ala Asn Gly Val Val Thr Ser Ile Gln Asp 
            500                 505                 510         


Arg Tyr Gly Ser 
        515     


<210>  3427
<211>  441
<212>  PRT
<213>  homo sapiens

<400>  3427

Met Ala Leu Phe Gly Ala Leu Phe Leu Ala Leu Leu Ala Gly Ala His 
1               5                   10                  15      


Ala Glu Phe Pro Gly Cys Lys Ile Arg Val Thr Ser Lys Ala Leu Glu 
            20                  25                  30          


Leu Val Lys Gln Glu Gly Leu Arg Phe Leu Glu Gln Glu Leu Glu Thr 
        35                  40                  45              


Ile Thr Ile Pro Asp Leu Arg Gly Lys Glu Gly His Phe Tyr Tyr Asn 
    50                  55                  60                  


Ile Ser Glu Val Lys Val Thr Glu Leu Gln Leu Thr Ser Ser Glu Leu 
65                  70                  75                  80  


Asp Phe Gln Pro Gln Gln Glu Leu Met Leu Gln Ile Thr Asn Ala Ser 
                85                  90                  95      


Leu Gly Leu Arg Phe Arg Arg Gln Leu Leu Tyr Trp Phe Leu Lys Val 
            100                 105                 110         


Tyr Asp Phe Leu Ser Thr Phe Ile Thr Ser Gly Met Arg Phe Leu Leu 
        115                 120                 125             


Asn Gln Gln Ile Cys Pro Val Leu Tyr His Ala Gly Thr Val Leu Leu 
    130                 135                 140                 


Asn Ser Leu Leu Asp Thr Val Pro Val Arg Ser Ser Val Asp Glu Leu 
145                 150                 155                 160 


Val Gly Ile Asp Tyr Ser Leu Met Lys Asp Pro Val Ala Ser Thr Ser 
                165                 170                 175     


Asn Leu Asp Met Asp Phe Arg Gly Ala Phe Phe Pro Leu Thr Glu Arg 
            180                 185                 190         


Asn Trp Ser Leu Pro Asn Arg Ala Val Glu Pro Gln Leu Gln Glu Glu 
        195                 200                 205             


Glu Arg Met Val Tyr Val Ala Phe Ser Glu Phe Phe Phe Asp Ser Ala 
    210                 215                 220                 


Met Glu Ser Tyr Phe Arg Ala Gly Ala Leu Gln Leu Leu Leu Val Gly 
225                 230                 235                 240 


Asp Lys Val Pro His Asp Leu Asp Met Leu Leu Arg Ala Thr Tyr Phe 
                245                 250                 255     


Gly Ser Ile Val Leu Leu Ser Pro Ala Val Ile Asp Ser Pro Leu Lys 
            260                 265                 270         


Leu Glu Leu Arg Val Leu Ala Pro Pro Arg Cys Thr Ile Lys Pro Ser 
        275                 280                 285             


Gly Thr Thr Ile Ser Val Thr Ala Ser Val Thr Ile Ala Leu Val Pro 
    290                 295                 300                 


Pro Asp Gln Pro Glu Val Gln Leu Ser Ser Met Thr Met Asp Ala Arg 
305                 310                 315                 320 


Leu Ser Ala Lys Met Ala Leu Arg Gly Lys Ala Leu Arg Thr Gln Leu 
                325                 330                 335     


Asp Leu Arg Arg Phe Arg Ile Tyr Ser Asn His Ser Ala Leu Glu Ser 
            340                 345                 350         


Leu Ala Leu Ile Pro Leu Gln Ala Pro Leu Lys Thr Met Leu Gln Ile 
        355                 360                 365             


Gly Val Met Pro Met Leu Asn Glu Arg Thr Trp Arg Gly Val Gln Ile 
    370                 375                 380                 


Pro Leu Pro Glu Gly Ile Asn Phe Val His Glu Val Val Thr Asn His 
385                 390                 395                 400 


Ala Gly Phe Leu Thr Ile Gly Ala Asp Leu His Phe Ala Lys Gly Leu 
                405                 410                 415     


Arg Glu Val Ile Glu Lys Asn Arg Pro Ala Asp Val Arg Ala Ser Thr 
            420                 425                 430         


Ala Pro Thr Pro Ser Thr Ala Ala Val 
        435                 440     


<210>  3428
<211>  982
<212>  PRT
<213>  homo sapiens

<400>  3428

Met Ala Asn Ser Met Asn Gly Arg Asn Pro Gly Gly Arg Gly Gly Asn 
1               5                   10                  15      


Pro Arg Lys Gly Arg Ile Leu Gly Ile Ile Asp Ala Ile Gln Asp Ala 
            20                  25                  30          


Val Gly Pro Pro Lys Gln Ala Ala Ala Asp Arg Arg Thr Val Glu Lys 
        35                  40                  45              


Thr Trp Lys Leu Met Asp Lys Val Val Arg Leu Cys Gln Asn Pro Lys 
    50                  55                  60                  


Leu Gln Leu Lys Asn Ser Pro Pro Tyr Ile Leu Asp Ile Leu Pro Asp 
65                  70                  75                  80  


Thr Tyr Gln His Leu Arg Leu Ile Leu Ser Lys Tyr Asp Asp Asn Gln 
                85                  90                  95      


Lys Leu Ala Gln Leu Ser Glu Asn Glu Tyr Phe Lys Ile Tyr Ile Asp 
            100                 105                 110         


Ser Leu Met Lys Lys Ser Lys Arg Ala Ile Arg Leu Phe Lys Glu Gly 
        115                 120                 125             


Lys Glu Arg Met Tyr Glu Glu Gln Ser Gln Asp Arg Arg Asn Leu Thr 
    130                 135                 140                 


Lys Leu Ser Leu Ile Phe Ser His Met Leu Ala Glu Ile Lys Ala Ile 
145                 150                 155                 160 


Phe Pro Asn Gly Gln Phe Gln Gly Asp Asn Phe Arg Ile Thr Lys Ala 
                165                 170                 175     


Asp Ala Ala Glu Phe Trp Arg Lys Phe Phe Gly Asp Lys Thr Ile Val 
            180                 185                 190         


Pro Trp Lys Val Phe Arg Gln Cys Leu His Glu Val His Gln Ile Ser 
        195                 200                 205             


Ser Gly Leu Glu Ala Met Ala Leu Lys Ser Thr Ile Asp Leu Thr Cys 
    210                 215                 220                 


Asn Asp Tyr Ile Ser Val Phe Glu Phe Asp Ile Phe Thr Arg Leu Phe 
225                 230                 235                 240 


Gln Pro Trp Gly Ser Ile Leu Arg Asn Trp Asn Phe Leu Ala Val Thr 
                245                 250                 255     


His Pro Gly Tyr Met Ala Phe Leu Thr Tyr Asp Glu Val Lys Ala Arg 
            260                 265                 270         


Leu Gln Lys Tyr Ser Thr Lys Pro Gly Ser Tyr Ile Phe Arg Leu Ser 
        275                 280                 285             


Cys Thr Arg Leu Gly Gln Trp Ala Ile Gly Tyr Val Thr Gly Asp Gly 
    290                 295                 300                 


Asn Ile Leu Gln Thr Ile Pro His Asn Lys Pro Leu Phe Gln Ala Leu 
305                 310                 315                 320 


Ile Asp Gly Ser Arg Glu Gly Phe Tyr Leu Tyr Pro Asp Gly Arg Ser 
                325                 330                 335     


Tyr Asn Pro Asp Leu Thr Gly Leu Cys Glu Pro Thr Pro His Asp His 
            340                 345                 350         


Ile Lys Val Thr Gln Glu Gln Tyr Glu Leu Tyr Cys Glu Met Gly Ser 
        355                 360                 365             


Thr Phe Gln Leu Cys Lys Ile Cys Ala Glu Asn Asp Lys Asp Val Lys 
    370                 375                 380                 


Ile Glu Pro Cys Gly His Leu Met Cys Thr Ser Cys Leu Thr Ala Trp 
385                 390                 395                 400 


Gln Glu Ser Asp Gly Gln Gly Cys Pro Phe Cys Arg Cys Glu Ile Lys 
                405                 410                 415     


Gly Thr Glu Pro Ile Ile Val Asp Pro Phe Asp Pro Arg Asp Glu Gly 
            420                 425                 430         


Ser Arg Cys Cys Ser Ile Ile Asp Pro Phe Gly Met Pro Met Leu Asp 
        435                 440                 445             


Leu Asp Asp Asp Asp Asp Arg Glu Glu Ser Leu Met Met Asn Arg Leu 
    450                 455                 460                 


Ala Asn Val Arg Lys Cys Thr Asp Arg Gln Asn Ser Pro Val Thr Ser 
465                 470                 475                 480 


Pro Gly Ser Ser Pro Leu Ala Gln Arg Arg Lys Pro Gln Pro Asp Pro 
                485                 490                 495     


Leu Gln Ile Pro His Leu Ser Leu Pro Pro Val Pro Pro Arg Leu Asp 
            500                 505                 510         


Leu Ile Gln Lys Gly Ile Val Arg Ser Pro Cys Gly Ser Pro Thr Gly 
        515                 520                 525             


Ser Pro Lys Ser Ser Pro Cys Met Val Arg Lys Gln Asp Lys Pro Leu 
    530                 535                 540                 


Pro Ala Pro Pro Pro Pro Leu Arg Asp Pro Pro Pro Pro Pro Pro Glu 
545                 550                 555                 560 


Arg Pro Pro Pro Ile Pro Pro Asp Asn Arg Leu Ser Arg His Ile His 
                565                 570                 575     


His Val Glu Ser Val Pro Ser Arg Asp Pro Pro Met Pro Leu Glu Ala 
            580                 585                 590         


Trp Cys Pro Arg Asp Val Phe Gly Thr Asn Gln Leu Val Gly Cys Arg 
        595                 600                 605             


Leu Leu Gly Glu Gly Ser Pro Lys Pro Gly Ile Thr Ala Ser Ser Asn 
    610                 615                 620                 


Val Asn Gly Arg His Ser Arg Val Gly Ser Asp Pro Val Leu Met Arg 
625                 630                 635                 640 


Lys His Arg Arg His Asp Leu Pro Leu Glu Gly Ala Lys Val Phe Ser 
                645                 650                 655     


Asn Gly His Leu Gly Ser Glu Glu Tyr Asp Val Pro Pro Arg Leu Ser 
            660                 665                 670         


Pro Pro Pro Pro Val Thr Thr Leu Leu Pro Ser Ile Lys Cys Thr Gly 
        675                 680                 685             


Pro Leu Ala Asn Ser Leu Ser Glu Lys Thr Arg Asp Pro Val Glu Glu 
    690                 695                 700                 


Asp Asp Asp Glu Tyr Lys Ile Pro Ser Ser His Pro Val Ser Leu Asn 
705                 710                 715                 720 


Ser Gln Pro Ser His Cys His Asn Val Lys Pro Pro Val Arg Ser Cys 
                725                 730                 735     


Asp Asn Gly His Cys Met Leu Asn Gly Thr His Gly Pro Ser Ser Glu 
            740                 745                 750         


Lys Lys Ser Asn Ile Pro Asp Leu Ser Ile Tyr Leu Lys Gly Asp Val 
        755                 760                 765             


Phe Asp Ser Ala Ser Asp Pro Val Pro Leu Pro Pro Ala Arg Pro Pro 
    770                 775                 780                 


Thr Arg Asp Asn Pro Lys His Gly Ser Ser Leu Asn Arg Thr Pro Ser 
785                 790                 795                 800 


Asp Tyr Asp Leu Leu Ile Pro Pro Leu Gly Glu Asp Ala Phe Asp Ala 
                805                 810                 815     


Leu Pro Pro Ser Leu Pro Pro Pro Pro Pro Pro Ala Arg His Ser Leu 
            820                 825                 830         


Ile Glu His Ser Lys Pro Pro Gly Ser Ser Ser Arg Pro Ser Ser Gly 
        835                 840                 845             


Gln Asp Leu Phe Leu Leu Pro Ser Asp Pro Phe Val Asp Leu Ala Ser 
    850                 855                 860                 


Gly Gln Val Pro Leu Pro Pro Ala Arg Arg Leu Pro Gly Glu Asn Val 
865                 870                 875                 880 


Lys Thr Asn Arg Thr Ser Gln Asp Tyr Asp Gln Leu Pro Ser Cys Ser 
                885                 890                 895     


Asp Gly Ser Gln Ala Pro Ala Arg Pro Pro Lys Pro Arg Pro Arg Arg 
            900                 905                 910         


Thr Ala Pro Glu Ile His His Arg Lys Pro His Gly Pro Glu Ala Ala 
        915                 920                 925             


Leu Glu Asn Val Asp Ala Lys Ile Ala Lys Leu Met Gly Glu Gly Tyr 
    930                 935                 940                 


Ala Phe Glu Glu Val Lys Arg Ala Leu Glu Ile Ala Gln Asn Asn Val 
945                 950                 955                 960 


Glu Val Ala Arg Ser Ile Leu Arg Glu Phe Ala Phe Pro Pro Pro Val 
                965                 970                 975     


Ser Pro Arg Leu Asn Leu 
            980         


<210>  3429
<211>  277
<212>  PRT
<213>  homo sapiens

<400>  3429

Met Ser Ser Gly Ile His Val Ala Leu Val Thr Gly Gly Asn Lys Gly 
1               5                   10                  15      


Ile Gly Leu Ala Ile Val Arg Asp Leu Cys Arg Leu Phe Ser Gly Asp 
            20                  25                  30          


Val Val Leu Thr Ala Arg Asp Val Thr Arg Gly Gln Ala Ala Val Gln 
        35                  40                  45              


Gln Leu Gln Ala Glu Gly Leu Ser Pro Arg Phe His Gln Leu Asp Ile 
    50                  55                  60                  


Asp Asp Leu Gln Ser Ile Arg Ala Leu Arg Asp Phe Leu Arg Lys Glu 
65                  70                  75                  80  


Tyr Gly Gly Leu Asp Val Leu Val Asn Asn Ala Gly Ile Ala Phe Lys 
                85                  90                  95      


Val Ala Asp Pro Thr Pro Phe His Ile Gln Ala Glu Val Thr Met Lys 
            100                 105                 110         


Thr Asn Phe Phe Gly Thr Arg Asp Val Cys Thr Glu Leu Leu Pro Leu 
        115                 120                 125             


Ile Lys Pro Gln Gly Arg Val Val Asn Val Ser Ser Ile Met Ser Val 
    130                 135                 140                 


Arg Ala Leu Lys Ser Cys Ser Pro Glu Leu Gln Gln Lys Phe Arg Ser 
145                 150                 155                 160 


Glu Thr Ile Thr Glu Glu Glu Leu Val Gly Leu Met Asn Lys Phe Val 
                165                 170                 175     


Glu Asp Thr Lys Lys Gly Val His Gln Lys Glu Gly Trp Pro Ser Ser 
            180                 185                 190         


Ala Tyr Gly Val Thr Lys Ile Gly Val Thr Val Leu Ser Arg Ile His 
        195                 200                 205             


Ala Arg Lys Leu Ser Glu Gln Arg Lys Gly Asp Lys Ile Leu Leu Asn 
    210                 215                 220                 


Ala Cys Cys Pro Gly Trp Val Arg Thr Asp Met Ala Gly Pro Lys Ala 
225                 230                 235                 240 


Thr Lys Ser Pro Glu Glu Gly Ala Glu Thr Pro Val Tyr Leu Ala Leu 
                245                 250                 255     


Leu Pro Pro Asp Ala Glu Gly Pro His Gly Gln Phe Val Ser Glu Lys 
            260                 265                 270         


Arg Val Glu Gln Trp 
        275         


<210>  3430
<211>  341
<212>  PRT
<213>  homo sapiens

<400>  3430

Met Glu Arg Glu Lys Glu Gln Phe Arg Lys Leu Phe Ile Gly Gly Leu 
1               5                   10                  15      


Ser Phe Glu Thr Thr Glu Glu Ser Leu Arg Asn Tyr Tyr Glu Gln Trp 
            20                  25                  30          


Gly Lys Leu Thr Asp Cys Val Val Met Arg Asp Pro Ala Ser Lys Arg 
        35                  40                  45              


Ser Arg Gly Phe Gly Phe Val Thr Phe Ser Ser Met Ala Glu Val Asp 
    50                  55                  60                  


Ala Ala Met Ala Ala Arg Pro His Ser Ile Asp Gly Arg Val Val Glu 
65                  70                  75                  80  


Pro Lys Arg Ala Val Ala Arg Glu Glu Ser Gly Lys Pro Gly Ala His 
                85                  90                  95      


Val Thr Val Lys Lys Leu Phe Val Gly Gly Ile Lys Glu Asp Thr Glu 
            100                 105                 110         


Glu His His Leu Arg Asp Tyr Phe Glu Glu Tyr Gly Lys Ile Asp Thr 
        115                 120                 125             


Ile Glu Ile Ile Thr Asp Arg Gln Ser Gly Lys Lys Arg Gly Phe Gly 
    130                 135                 140                 


Phe Val Thr Phe Asp Asp His Asp Pro Val Asp Lys Ile Val Leu Gln 
145                 150                 155                 160 


Lys Tyr His Thr Ile Asn Gly His Asn Ala Glu Val Arg Lys Ala Leu 
                165                 170                 175     


Ser Arg Gln Glu Met Gln Glu Val Gln Ser Ser Arg Ser Gly Arg Gly 
            180                 185                 190         


Gly Asn Phe Gly Phe Gly Asp Ser Arg Gly Gly Gly Gly Asn Phe Gly 
        195                 200                 205             


Pro Gly Pro Gly Ser Asn Phe Arg Gly Gly Ser Asp Gly Tyr Gly Ser 
    210                 215                 220                 


Gly Arg Gly Phe Gly Asp Gly Tyr Asn Gly Tyr Gly Gly Gly Pro Gly 
225                 230                 235                 240 


Gly Gly Asn Phe Gly Gly Ser Pro Gly Tyr Gly Gly Gly Arg Gly Gly 
                245                 250                 255     


Tyr Gly Gly Gly Gly Pro Gly Tyr Gly Asn Gln Gly Gly Gly Tyr Gly 
            260                 265                 270         


Gly Gly Tyr Asp Asn Tyr Gly Gly Gly Asn Tyr Gly Ser Gly Asn Tyr 
        275                 280                 285             


Asn Asp Phe Gly Asn Tyr Asn Gln Gln Pro Ser Asn Tyr Gly Pro Met 
    290                 295                 300                 


Lys Ser Gly Asn Phe Gly Gly Ser Arg Asn Met Gly Gly Pro Tyr Gly 
305                 310                 315                 320 


Gly Gly Asn Tyr Gly Pro Gly Gly Ser Gly Gly Ser Gly Gly Tyr Gly 
                325                 330                 335     


Gly Arg Ser Arg Tyr 
            340     


<210>  3431
<211>  306
<212>  PRT
<213>  homo sapiens

<400>  3431

Met Ser Glu Glu Gln Phe Gly Gly Asp Gly Ala Ala Ala Ala Ala Thr 
1               5                   10                  15      


Ala Ala Val Gly Gly Ser Ala Gly Glu Gln Glu Gly Ala Met Val Ala 
            20                  25                  30          


Ala Thr Gln Gly Ala Ala Ala Ala Ala Gly Ser Gly Ala Gly Thr Gly 
        35                  40                  45              


Gly Gly Thr Ala Ser Gly Gly Thr Glu Gly Gly Ser Ala Glu Ser Glu 
    50                  55                  60                  


Gly Ala Lys Ile Asp Ala Ser Lys Asn Glu Glu Asp Glu Gly His Ser 
65                  70                  75                  80  


Asn Ser Ser Pro Arg His Ser Glu Ala Ala Thr Ala Gln Arg Glu Glu 
                85                  90                  95      


Trp Lys Met Phe Ile Gly Gly Leu Ser Trp Asp Thr Thr Lys Lys Asp 
            100                 105                 110         


Leu Lys Asp Tyr Phe Ser Lys Phe Gly Glu Val Val Asp Cys Thr Leu 
        115                 120                 125             


Lys Leu Asp Pro Ile Thr Gly Arg Ser Arg Gly Phe Gly Phe Val Leu 
    130                 135                 140                 


Phe Lys Glu Ser Glu Ser Val Asp Lys Val Met Asp Gln Lys Glu His 
145                 150                 155                 160 


Lys Leu Asn Gly Lys Val Ile Asp Pro Lys Arg Ala Lys Ala Met Lys 
                165                 170                 175     


Thr Lys Glu Pro Val Lys Lys Ile Phe Val Gly Gly Leu Ser Pro Asp 
            180                 185                 190         


Thr Pro Glu Glu Lys Ile Arg Glu Tyr Phe Gly Gly Phe Gly Glu Val 
        195                 200                 205             


Glu Ser Ile Glu Leu Pro Met Asp Asn Lys Thr Asn Lys Arg Arg Gly 
    210                 215                 220                 


Phe Cys Phe Ile Thr Phe Lys Glu Glu Glu Pro Val Lys Lys Ile Met 
225                 230                 235                 240 


Glu Lys Lys Tyr His Asn Val Gly Leu Ser Lys Cys Glu Ile Lys Val 
                245                 250                 255     


Ala Met Ser Lys Glu Gln Tyr Gln Gln Gln Gln Gln Trp Gly Ser Arg 
            260                 265                 270         


Gly Gly Phe Ala Gly Arg Ala Arg Gly Arg Gly Gly Asp Gln Gln Ser 
        275                 280                 285             


Gly Tyr Gly Lys Val Ser Arg Arg Gly Gly His Gln Asn Ser Tyr Lys 
    290                 295                 300                 


Pro Tyr 
305     


<210>  3432
<211>  1352
<212>  PRT
<213>  homo sapiens

<400>  3432

Met Ala His Thr Thr Lys Val Asn Gly Ser Ala Ser Gly Lys Ala Gly 
1               5                   10                  15      


Asp Ile Leu Ser Gly Asp Gln Asp Lys Glu Gln Lys Asp Pro Tyr Phe 
            20                  25                  30          


Val Glu Thr Pro Tyr Gly Tyr Gln Leu Asp Leu Asp Phe Leu Lys Tyr 
        35                  40                  45              


Val Asp Asp Ile Gln Lys Gly Asn Thr Ile Lys Arg Leu Asn Ile Gln 
    50                  55                  60                  


Lys Arg Arg Lys Pro Ser Val Pro Cys Pro Glu Pro Arg Thr Thr Ser 
65                  70                  75                  80  


Gly Gln Gln Gly Ile Trp Thr Ser Thr Glu Ser Leu Ser Ser Ser Asn 
                85                  90                  95      


Ser Asp Asp Asn Lys Gln Cys Pro Asn Phe Leu Ile Ala Arg Ser Gln 
            100                 105                 110         


Val Thr Ser Thr Pro Ile Ser Lys Pro Pro Pro Pro Leu Glu Thr Ser 
        115                 120                 125             


Leu Pro Phe Leu Thr Ile Pro Glu Asn Arg Gln Leu Pro Pro Pro Ser 
    130                 135                 140                 


Pro Gln Leu Pro Lys His Asn Leu His Val Thr Lys Thr Leu Met Glu 
145                 150                 155                 160 


Thr Arg Arg Arg Leu Glu Gln Glu Arg Ala Thr Met Gln Met Thr Pro 
                165                 170                 175     


Gly Glu Phe Arg Arg Pro Arg Leu Ala Ser Phe Gly Gly Met Gly Thr 
            180                 185                 190         


Thr Ser Ser Leu Pro Ser Phe Val Gly Ser Gly Asn His Asn Pro Ala 
        195                 200                 205             


Lys His Gln Leu Gln Asn Gly Tyr Gln Gly Asn Gly Asp Tyr Gly Ser 
    210                 215                 220                 


Tyr Ala Pro Ala Ala Pro Thr Thr Ser Ser Met Gly Ser Ser Ile Arg 
225                 230                 235                 240 


His Ser Pro Leu Ser Ser Gly Ile Ser Thr Pro Val Thr Asn Val Ser 
                245                 250                 255     


Pro Met His Leu Gln His Ile Arg Glu Gln Met Ala Ile Ala Leu Lys 
            260                 265                 270         


Arg Leu Lys Glu Leu Glu Glu Gln Val Arg Thr Ile Pro Val Leu Gln 
        275                 280                 285             


Val Lys Ile Ser Val Leu Gln Glu Glu Lys Arg Gln Leu Val Ser Gln 
    290                 295                 300                 


Leu Lys Asn Gln Arg Ala Ala Ser Gln Ile Asn Val Cys Gly Val Arg 
305                 310                 315                 320 


Lys Arg Ser Tyr Ser Ala Gly Asn Ala Ser Gln Leu Glu Gln Leu Ser 
                325                 330                 335     


Arg Ala Arg Arg Ser Gly Gly Glu Leu Tyr Ile Asp Tyr Glu Glu Glu 
            340                 345                 350         


Glu Met Glu Thr Val Glu Gln Ser Thr Gln Arg Ile Lys Glu Phe Arg 
        355                 360                 365             


Gln Leu Thr Ala Asp Met Gln Ala Leu Glu Gln Lys Ile Gln Asp Ser 
    370                 375                 380                 


Ser Cys Glu Ala Ser Ser Glu Leu Arg Glu Asn Gly Glu Cys Arg Ser 
385                 390                 395                 400 


Val Ala Val Gly Ala Glu Glu Asn Met Asn Asp Ile Val Val Tyr His 
                405                 410                 415     


Arg Gly Ser Arg Ser Cys Lys Asp Ala Ala Val Gly Thr Leu Val Glu 
            420                 425                 430         


Met Arg Asn Cys Gly Val Ser Val Thr Glu Ala Met Leu Gly Val Met 
        435                 440                 445             


Thr Glu Ala Asp Lys Glu Ile Glu Leu Gln Gln Gln Thr Ile Glu Ser 
    450                 455                 460                 


Leu Lys Glu Lys Ile Tyr Arg Leu Glu Val Gln Leu Arg Glu Thr Thr 
465                 470                 475                 480 


His Asp Arg Glu Met Thr Lys Leu Lys Gln Glu Leu Gln Ala Ala Gly 
                485                 490                 495     


Ser Arg Lys Lys Val Asp Lys Ala Thr Met Ala Gln Pro Leu Val Phe 
            500                 505                 510         


Ser Lys Val Val Glu Ala Val Val Gln Thr Arg Asp Gln Met Val Gly 
        515                 520                 525             


Ser His Met Asp Leu Val Asp Thr Cys Val Gly Thr Ser Val Glu Thr 
    530                 535                 540                 


Asn Ser Val Gly Ile Ser Cys Gln Pro Glu Cys Lys Asn Lys Val Val 
545                 550                 555                 560 


Gly Pro Glu Leu Pro Met Asn Trp Trp Ile Val Lys Glu Arg Val Glu 
                565                 570                 575     


Met His Asp Arg Cys Ala Gly Arg Ser Val Glu Met Cys Asp Lys Ser 
            580                 585                 590         


Val Ser Val Glu Val Ser Val Cys Glu Thr Gly Ser Asn Thr Glu Glu 
        595                 600                 605             


Ser Val Asn Asp Leu Thr Leu Leu Lys Thr Asn Leu Asn Leu Lys Glu 
    610                 615                 620                 


Val Arg Ser Ile Gly Cys Gly Asp Cys Ser Val Asp Val Thr Val Cys 
625                 630                 635                 640 


Ser Pro Lys Glu Cys Ala Ser Arg Gly Val Asn Thr Glu Ala Val Ser 
                645                 650                 655     


Gln Val Glu Ala Ala Val Met Ala Val Pro Arg Thr Ala Asp Gln Asp 
            660                 665                 670         


Thr Ser Thr Asp Leu Glu Gln Val His Gln Phe Thr Asn Thr Glu Thr 
        675                 680                 685             


Ala Thr Leu Ile Glu Ser Cys Thr Asn Thr Cys Leu Ser Thr Leu Asp 
    690                 695                 700                 


Lys Gln Thr Ser Thr Gln Thr Val Glu Thr Arg Thr Val Ala Val Gly 
705                 710                 715                 720 


Glu Gly Arg Val Lys Asp Ile Asn Ser Ser Thr Lys Thr Arg Ser Ile 
                725                 730                 735     


Gly Val Gly Thr Leu Leu Ser Gly His Ser Gly Phe Asp Arg Pro Ser 
            740                 745                 750         


Ala Val Lys Thr Lys Glu Ser Gly Val Gly Gln Ile Asn Ile Asn Asp 
        755                 760                 765             


Asn Tyr Leu Val Gly Leu Lys Met Arg Thr Ile Ala Cys Gly Pro Pro 
    770                 775                 780                 


Gln Leu Thr Val Gly Leu Thr Ala Ser Arg Arg Ser Val Gly Val Gly 
785                 790                 795                 800 


Asp Asp Pro Val Gly Glu Ser Leu Glu Asn Pro Gln Pro Gln Ala Pro 
                805                 810                 815     


Leu Gly Met Met Thr Gly Leu Asp His Tyr Ile Glu Arg Ile Gln Lys 
            820                 825                 830         


Leu Leu Ala Glu Gln Gln Thr Leu Leu Ala Glu Asn Tyr Ser Glu Leu 
        835                 840                 845             


Ala Glu Ala Phe Gly Glu Pro His Ser Gln Met Gly Ser Leu Asn Ser 
    850                 855                 860                 


Gln Leu Ile Ser Thr Leu Ser Ser Ile Asn Ser Val Met Lys Ser Ala 
865                 870                 875                 880 


Ser Thr Glu Glu Leu Arg Asn Pro Asp Phe Gln Lys Thr Ser Leu Gly 
                885                 890                 895     


Lys Ile Thr Gly Asn Tyr Leu Gly Tyr Thr Cys Lys Cys Gly Gly Leu 
            900                 905                 910         


Gln Ser Gly Ser Pro Leu Ser Ser Gln Thr Ser Gln Pro Glu Gln Glu 
        915                 920                 925             


Val Gly Thr Ser Glu Gly Lys Pro Ile Ser Ser Leu Asp Ala Phe Pro 
    930                 935                 940                 


Thr Gln Glu Gly Thr Leu Ser Pro Val Asn Leu Thr Asp Asp Gln Ile 
945                 950                 955                 960 


Ala Ala Gly Leu Tyr Ala Cys Thr Asn Asn Glu Ser Thr Leu Lys Ser 
                965                 970                 975     


Ile Met Lys Lys Lys Asp Gly Asn Lys Asp Ser Asn Gly Ala Lys Lys 
            980                 985                 990         


Asn Leu Gln Phe Val Gly Ile Asn  Gly Gly Tyr Glu Thr  Thr Ser Ser 
        995                 1000                 1005             


Asp Asp  Ser Ser Ser Asp Glu  Ser Ser Ser Ser Glu  Ser Asp Asp 
    1010                 1015                 1020             


Glu Cys  Asp Val Ile Glu Tyr  Pro Leu Glu Glu Glu  Glu Glu Glu 
    1025                 1030                 1035             


Glu Asp  Glu Asp Thr Arg Gly  Met Ala Glu Gly His  His Ala Val 
    1040                 1045                 1050             


Asn Ile  Glu Gly Leu Lys Ser  Ala Arg Val Glu Asp  Glu Met Gln 
    1055                 1060                 1065             


Val Gln  Glu Cys Glu Pro Glu  Lys Val Glu Ile Arg  Glu Arg Tyr 
    1070                 1075                 1080             


Glu Leu  Ser Glu Lys Met Leu  Ser Ala Cys Asn Leu  Leu Lys Asn 
    1085                 1090                 1095             


Thr Ile  Asn Asp Pro Lys Ala  Leu Thr Ser Lys Asp  Met Arg Phe 
    1100                 1105                 1110             


Cys Leu  Asn Thr Leu Gln His  Glu Trp Phe Arg Val  Ser Ser Gln 
    1115                 1120                 1125             


Lys Ser  Ala Ile Pro Ala Met  Val Gly Asp Tyr Ile  Ala Ala Phe 
    1130                 1135                 1140             


Glu Ala  Ile Ser Pro Asp Val  Leu Arg Tyr Val Ile  Asn Leu Ala 
    1145                 1150                 1155             


Asp Gly  Asn Gly Asn Thr Ala  Leu His Tyr Ser Val  Ser His Ser 
    1160                 1165                 1170             


Asn Phe  Glu Ile Val Lys Leu  Leu Leu Asp Ala Asp  Val Cys Asn 
    1175                 1180                 1185             


Val Asp  His Gln Asn Lys Ala  Gly Tyr Thr Pro Ile  Met Leu Ala 
    1190                 1195                 1200             


Ala Leu  Ala Ala Val Glu Ala  Glu Lys Asp Met Arg  Ile Val Glu 
    1205                 1210                 1215             


Glu Leu  Phe Gly Cys Gly Asp  Val Asn Ala Lys Ala  Ser Gln Ala 
    1220                 1225                 1230             


Gly Gln  Thr Ala Leu Met Leu  Ala Val Ser His Gly  Arg Ile Asp 
    1235                 1240                 1245             


Met Val  Lys Gly Leu Leu Ala  Cys Gly Ala Asp Val  Asn Ile Gln 
    1250                 1255                 1260             


Asp Asp  Glu Gly Ser Thr Ala  Leu Met Cys Ala Ser  Glu His Gly 
    1265                 1270                 1275             


His Val  Glu Ile Val Lys Leu  Leu Leu Ala Gln Pro  Gly Cys Asn 
    1280                 1285                 1290             


Gly His  Leu Glu Asp Asn Asp  Gly Ser Thr Ala Leu  Ser Ile Ala 
    1295                 1300                 1305             


Leu Glu  Ala Gly His Lys Asp  Ile Ala Val Leu Leu  Tyr Ala His 
    1310                 1315                 1320             


Val Asn  Phe Ala Lys Ala Gln  Ser Pro Gly Thr Pro  Arg Leu Gly 
    1325                 1330                 1335             


Arg Lys  Thr Ser Pro Gly Pro  Thr His Arg Gly Ser  Phe Asp 
    1340                 1345                 1350         


<210>  3433
<211>  1189
<212>  PRT
<213>  homo sapiens

<400>  3433

Met Ala Arg Gln Pro Pro Pro Pro Trp Val His Ala Ala Phe Leu Leu 
1               5                   10                  15      


Cys Leu Leu Ser Leu Gly Gly Ala Ile Glu Ile Pro Met Asp Leu Thr 
            20                  25                  30          


Gln Pro Pro Thr Ile Thr Lys Gln Ser Ala Lys Asp His Ile Val Asp 
        35                  40                  45              


Pro Arg Asp Asn Ile Leu Ile Glu Cys Glu Ala Lys Gly Asn Pro Ala 
    50                  55                  60                  


Pro Ser Phe His Trp Thr Arg Asn Ser Arg Phe Phe Asn Ile Ala Lys 
65                  70                  75                  80  


Asp Pro Arg Val Ser Met Arg Arg Arg Ser Gly Thr Leu Val Ile Asp 
                85                  90                  95      


Phe Arg Ser Gly Gly Arg Pro Glu Glu Tyr Glu Gly Glu Tyr Gln Cys 
            100                 105                 110         


Phe Ala Arg Asn Lys Phe Gly Thr Ala Leu Ser Asn Arg Ile Arg Leu 
        115                 120                 125             


Gln Val Ser Lys Ser Pro Leu Trp Pro Lys Glu Asn Leu Asp Pro Val 
    130                 135                 140                 


Val Val Gln Glu Gly Ala Pro Leu Thr Leu Gln Cys Asn Pro Pro Pro 
145                 150                 155                 160 


Gly Leu Pro Ser Pro Val Ile Phe Trp Met Ser Ser Ser Met Glu Pro 
                165                 170                 175     


Ile Thr Gln Asp Lys Arg Val Ser Gln Gly His Asn Gly Asp Leu Tyr 
            180                 185                 190         


Phe Ser Asn Val Met Leu Gln Asp Met Gln Thr Asp Tyr Ser Cys Asn 
        195                 200                 205             


Ala Arg Phe His Phe Thr His Thr Ile Gln Gln Lys Asn Pro Phe Thr 
    210                 215                 220                 


Leu Lys Val Leu Thr Asn His Pro Tyr Asn Asp Ser Ser Leu Arg Asn 
225                 230                 235                 240 


His Pro Asp Met Tyr Ser Ala Arg Gly Val Ala Glu Arg Thr Pro Ser 
                245                 250                 255     


Phe Met Tyr Pro Gln Gly Thr Ala Ser Ser Gln Met Val Leu Arg Gly 
            260                 265                 270         


Met Asp Leu Leu Leu Glu Cys Ile Ala Ser Gly Val Pro Thr Pro Asp 
        275                 280                 285             


Ile Ala Trp Tyr Lys Lys Gly Gly Asp Leu Pro Ser Asp Lys Ala Lys 
    290                 295                 300                 


Phe Glu Asn Phe Asn Lys Ala Leu Arg Ile Thr Asn Val Ser Glu Glu 
305                 310                 315                 320 


Asp Ser Gly Glu Tyr Phe Cys Leu Ala Ser Asn Lys Met Gly Ser Ile 
                325                 330                 335     


Arg His Thr Ile Ser Val Arg Val Lys Ala Ala Pro Tyr Trp Leu Asp 
            340                 345                 350         


Glu Pro Lys Asn Leu Ile Leu Ala Pro Gly Glu Asp Gly Arg Leu Val 
        355                 360                 365             


Cys Arg Ala Asn Gly Asn Pro Lys Pro Thr Val Gln Trp Met Val Asn 
    370                 375                 380                 


Gly Glu Pro Leu Gln Ser Ala Pro Pro Asn Pro Asn Arg Glu Val Ala 
385                 390                 395                 400 


Gly Asp Thr Ile Ile Phe Arg Asp Thr Gln Ile Ser Ser Arg Ala Val 
                405                 410                 415     


Tyr Gln Cys Asn Thr Ser Asn Glu His Gly Tyr Leu Leu Ala Asn Ala 
            420                 425                 430         


Phe Val Ser Val Leu Asp Val Pro Pro Arg Met Leu Ser Pro Arg Asn 
        435                 440                 445             


Gln Leu Ile Arg Val Ile Leu Tyr Asn Arg Thr Arg Leu Asp Cys Pro 
    450                 455                 460                 


Phe Phe Gly Ser Pro Ile Pro Thr Leu Arg Trp Phe Lys Asn Gly Gln 
465                 470                 475                 480 


Gly Ser Asn Leu Asp Gly Gly Asn Tyr His Val Tyr Glu Asn Gly Ser 
                485                 490                 495     


Leu Glu Ile Lys Met Ile Arg Lys Glu Asp Gln Gly Ile Tyr Thr Cys 
            500                 505                 510         


Val Ala Thr Asn Ile Leu Gly Lys Ala Glu Asn Gln Val Arg Leu Glu 
        515                 520                 525             


Val Lys Asp Pro Thr Arg Ile Tyr Arg Met Pro Glu Asp Gln Val Ala 
    530                 535                 540                 


Arg Arg Gly Thr Thr Val Gln Leu Glu Cys Arg Val Lys His Asp Pro 
545                 550                 555                 560 


Ser Leu Lys Leu Thr Val Ser Trp Leu Lys Asp Asp Glu Pro Leu Tyr 
                565                 570                 575     


Ile Gly Asn Arg Met Lys Lys Glu Asp Asp Ser Leu Thr Ile Phe Gly 
            580                 585                 590         


Val Ala Glu Arg Asp Gln Gly Ser Tyr Thr Cys Val Ala Ser Thr Glu 
        595                 600                 605             


Leu Asp Gln Asp Leu Ala Lys Ala Tyr Leu Thr Val Leu Ala Asp Gln 
    610                 615                 620                 


Ala Thr Pro Thr Asn Arg Leu Ala Ala Leu Pro Lys Gly Arg Pro Asp 
625                 630                 635                 640 


Arg Pro Arg Asp Leu Glu Leu Thr Asp Leu Ala Glu Arg Ser Val Arg 
                645                 650                 655     


Leu Thr Trp Ile Pro Gly Asp Ala Asn Asn Ser Pro Ile Thr Asp Tyr 
            660                 665                 670         


Val Val Gln Phe Glu Glu Asp Gln Phe Gln Pro Gly Val Trp His Asp 
        675                 680                 685             


His Ser Lys Tyr Pro Gly Ser Val Asn Ser Ala Val Leu Arg Leu Ser 
    690                 695                 700                 


Pro Tyr Val Asn Tyr Gln Phe Arg Val Ile Ala Ile Asn Glu Val Gly 
705                 710                 715                 720 


Ser Ser His Pro Ser Leu Pro Ser Glu Arg Tyr Arg Thr Ser Gly Ala 
                725                 730                 735     


Pro Pro Glu Ser Asn Pro Gly Asp Val Lys Gly Glu Gly Thr Arg Lys 
            740                 745                 750         


Asn Asn Met Glu Ile Thr Trp Thr Pro Met Asn Ala Thr Ser Ala Phe 
        755                 760                 765             


Gly Pro Asn Leu Arg Tyr Ile Val Lys Trp Arg Arg Arg Glu Thr Arg 
    770                 775                 780                 


Glu Ala Trp Asn Asn Val Thr Val Trp Gly Ser Arg Tyr Val Val Gly 
785                 790                 795                 800 


Gln Thr Pro Val Tyr Val Pro Tyr Glu Ile Arg Val Gln Ala Glu Asn 
                805                 810                 815     


Asp Phe Gly Lys Gly Pro Glu Pro Glu Ser Val Ile Gly Tyr Ser Gly 
            820                 825                 830         


Glu Asp Tyr Pro Arg Ala Ala Pro Thr Glu Val Lys Val Arg Val Met 
        835                 840                 845             


Asn Ser Thr Ala Ile Ser Leu Gln Trp Asn Arg Val Tyr Ser Asp Thr 
    850                 855                 860                 


Val Gln Gly Gln Leu Arg Glu Tyr Arg Ala Tyr Tyr Trp Arg Glu Ser 
865                 870                 875                 880 


Ser Leu Leu Lys Asn Leu Trp Val Ser Gln Lys Arg Gln Gln Ala Ser 
                885                 890                 895     


Phe Pro Gly Asp Arg Leu Arg Gly Val Val Ser Arg Leu Phe Pro Tyr 
            900                 905                 910         


Ser Asn Tyr Lys Leu Glu Met Val Val Val Asn Gly Arg Gly Asp Gly 
        915                 920                 925             


Pro Arg Ser Glu Thr Lys Glu Phe Thr Thr Pro Glu Gly Val Pro Ser 
    930                 935                 940                 


Ala Pro Arg Arg Phe Arg Val Arg Gln Pro Asn Leu Glu Thr Ile Asn 
945                 950                 955                 960 


Leu Glu Trp Asp His Pro Glu His Pro Asn Gly Ile Met Ile Gly Tyr 
                965                 970                 975     


Thr Leu Lys Tyr Val Ala Phe Asn Gly Thr Lys Val Gly Lys Gln Ile 
            980                 985                 990         


Val Glu Asn Phe Ser Pro Asn Gln  Thr Lys Phe Thr Val  Gln Arg Thr 
        995                 1000                 1005             


Asp Pro  Val Ser Arg Tyr Arg  Phe Thr Leu Ser Ala  Arg Thr Gln 
    1010                 1015                 1020             


Val Gly  Ser Gly Glu Ala Val  Thr Glu Glu Ser Pro  Ala Pro Pro 
    1025                 1030                 1035             


Asn Glu  Ala Thr Pro Thr Ala  Ala Tyr Thr Asn Asn  Gln Ala Asp 
    1040                 1045                 1050             


Ile Ala  Thr Gln Gly Trp Phe  Ile Gly Leu Met Cys  Ala Ile Ala 
    1055                 1060                 1065             


Leu Leu  Val Leu Ile Leu Leu  Ile Val Cys Phe Ile  Lys Arg Ser 
    1070                 1075                 1080             


Arg Gly  Gly Lys Tyr Pro Val  Arg Glu Lys Lys Asp  Val Pro Leu 
    1085                 1090                 1095             


Gly Pro  Glu Asp Pro Lys Glu  Glu Asp Gly Ser Phe  Asp Tyr Ser 
    1100                 1105                 1110             


Asp Glu  Asp Asn Lys Pro Leu  Gln Gly Ser Gln Thr  Ser Leu Asp 
    1115                 1120                 1125             


Gly Thr  Ile Lys Gln Gln Glu  Ser Asp Asp Ser Leu  Val Asp Tyr 
    1130                 1135                 1140             


Gly Glu  Gly Gly Glu Gly Gln  Phe Asn Glu Asp Gly  Ser Phe Ile 
    1145                 1150                 1155             


Gly Gln  Tyr Thr Val Lys Lys  Asp Lys Glu Glu Thr  Glu Gly Asn 
    1160                 1165                 1170             


Glu Ser  Ser Glu Ala Thr Ser  Pro Val Asn Ala Ile  Tyr Ser Leu 
    1175                 1180                 1185             


Ala 
    


<210>  3434
<211>  587
<212>  PRT
<213>  homo sapiens

<400>  3434

Met Ala Thr Ala Ala Tyr Glu Gln Leu Lys Leu His Ile Thr Pro Glu 
1               5                   10                  15      


Lys Phe Tyr Val Glu Ala Cys Asp Asp Gly Ala Asp Asp Val Leu Thr 
            20                  25                  30          


Ile Asp Arg Val Ser Thr Glu Val Thr Leu Ala Val Lys Lys Asp Val 
        35                  40                  45              


Pro Pro Ser Ala Val Thr Arg Pro Ile Phe Gly Ile Leu Gly Thr Ile 
    50                  55                  60                  


His Leu Val Ala Gly Asn Tyr Leu Ile Val Ile Thr Lys Lys Ile Lys 
65                  70                  75                  80  


Val Gly Glu Phe Phe Ser His Val Val Trp Lys Ala Thr Asp Phe Asp 
                85                  90                  95      


Val Leu Ser Tyr Lys Lys Thr Met Leu His Leu Thr Asp Ile Gln Leu 
            100                 105                 110         


Gln Asp Asn Lys Thr Phe Leu Ala Met Leu Asn His Val Leu Asn Val 
        115                 120                 125             


Asp Gly Phe Tyr Phe Ser Thr Thr Tyr Asp Leu Thr His Thr Leu Gln 
    130                 135                 140                 


Arg Leu Ser Asn Thr Ser Pro Glu Phe Gln Glu Met Ser Leu Leu Glu 
145                 150                 155                 160 


Arg Ala Asp Gln Arg Phe Val Trp Asn Gly His Leu Leu Arg Glu Leu 
                165                 170                 175     


Ser Ala Gln Pro Glu Val His Arg Phe Ala Leu Pro Val Leu His Gly 
            180                 185                 190         


Phe Ile Thr Met His Ser Cys Ser Ile Asn Gly Lys Tyr Phe Asp Trp 
        195                 200                 205             


Ile Leu Ile Ser Arg Arg Ser Cys Phe Arg Ala Gly Val Arg Tyr Tyr 
    210                 215                 220                 


Val Arg Gly Ile Asp Ser Glu Gly His Ala Ala Asn Phe Val Glu Thr 
225                 230                 235                 240 


Glu Gln Ile Val His Tyr Asn Gly Ser Lys Ala Ser Phe Val Gln Thr 
                245                 250                 255     


Arg Gly Ser Ile Pro Val Phe Trp Ser Gln Arg Pro Asn Leu Lys Tyr 
            260                 265                 270         


Lys Pro Leu Pro Gln Ile Ser Lys Val Ala Asn His Met Asp Gly Phe 
        275                 280                 285             


Gln Arg His Phe Asp Ser Gln Val Ile Ile Tyr Gly Lys Gln Val Ile 
    290                 295                 300                 


Ile Asn Leu Ile Asn Gln Lys Gly Ser Glu Lys Pro Leu Glu Gln Thr 
305                 310                 315                 320 


Phe Ala Thr Met Val Ser Ser Leu Gly Ser Gly Met Met Arg Tyr Ile 
                325                 330                 335     


Ala Phe Asp Phe His Lys Glu Cys Lys Asn Met Arg Trp Asp Arg Leu 
            340                 345                 350         


Ser Ile Leu Leu Asp Gln Val Ala Glu Met Gln Asp Glu Leu Ser Tyr 
        355                 360                 365             


Phe Leu Val Asp Ser Ala Gly Gln Val Val Ala Asn Gln Glu Gly Val 
    370                 375                 380                 


Phe Arg Ser Asn Cys Met Asp Cys Leu Asp Arg Thr Asn Val Ile Gln 
385                 390                 395                 400 


Ser Leu Leu Ala Arg Arg Ser Leu Gln Ala Gln Leu Gln Arg Leu Gly 
                405                 410                 415     


Val Leu His Val Gly Gln Lys Leu Glu Glu Gln Asp Glu Phe Glu Lys 
            420                 425                 430         


Ile Tyr Lys Asn Ala Trp Ala Asp Asn Ala Asn Ala Cys Ala Lys Gln 
        435                 440                 445             


Tyr Ala Gly Thr Gly Ala Leu Lys Thr Asp Phe Thr Arg Thr Gly Lys 
    450                 455                 460                 


Arg Thr His Leu Gly Leu Ile Met Asp Gly Trp Asn Ser Met Ile Arg 
465                 470                 475                 480 


Tyr Tyr Lys Asn Asn Phe Ser Asp Gly Phe Arg Gln Asp Ser Ile Asp 
                485                 490                 495     


Leu Phe Leu Gly Asn Tyr Ser Val Asp Glu Leu Glu Ser His Ser Pro 
            500                 505                 510         


Leu Ser Val Pro Arg Asp Trp Lys Phe Leu Ala Leu Pro Ile Ile Met 
        515                 520                 525             


Val Val Ala Phe Ser Met Cys Ile Ile Cys Leu Leu Met Ala Gly Asp 
    530                 535                 540                 


Thr Trp Thr Glu Thr Leu Ala Tyr Val Leu Phe Trp Gly Val Ala Ser 
545                 550                 555                 560 


Ile Gly Thr Phe Phe Ile Ile Leu Tyr Asn Gly Lys Asp Phe Val Asp 
                565                 570                 575     


Ala Pro Arg Leu Val Gln Lys Glu Lys Ile Asp 
            580                 585         


<210>  3435
<211>  1324
<212>  PRT
<213>  homo sapiens

<400>  3435

Met Ser Arg Arg Lys Gln Ala Lys Pro Gln His Phe Gln Ser Asp Pro 
1               5                   10                  15      


Glu Val Ala Ser Leu Pro Arg Arg Asp Gly Asp Thr Glu Lys Gly Gln 
            20                  25                  30          


Pro Ser Arg Pro Thr Lys Ser Lys Asp Ala His Val Cys Gly Arg Cys 
        35                  40                  45              


Cys Ala Glu Phe Phe Glu Leu Ser Asp Leu Leu Leu His Lys Lys Asn 
    50                  55                  60                  


Cys Thr Lys Asn Gln Leu Val Leu Ile Val Asn Glu Asn Pro Ala Ser 
65                  70                  75                  80  


Pro Pro Glu Thr Phe Ser Pro Ser Pro Pro Pro Asp Asn Pro Asp Glu 
                85                  90                  95      


Gln Met Asn Asp Thr Val Asn Lys Thr Asp Gln Val Asp Cys Ser Asp 
            100                 105                 110         


Leu Ser Glu His Asn Gly Leu Asp Arg Glu Glu Ser Met Glu Val Glu 
        115                 120                 125             


Ala Pro Val Ala Asn Lys Ser Gly Ser Gly Thr Ser Ser Gly Ser His 
    130                 135                 140                 


Ser Ser Thr Ala Pro Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Gly 
145                 150                 155                 160 


Gly Gly Gly Ser Ser Ser Thr Gly Thr Ser Ala Ile Thr Thr Ser Leu 
                165                 170                 175     


Pro Gln Leu Gly Asp Leu Thr Thr Leu Gly Asn Phe Ser Val Ile Asn 
            180                 185                 190         


Ser Asn Val Ile Ile Glu Asn Leu Gln Ser Thr Lys Val Ala Val Ala 
        195                 200                 205             


Gln Phe Ser Gln Glu Ala Arg Cys Gly Gly Ala Ser Gly Gly Lys Leu 
    210                 215                 220                 


Ala Val Pro Ala Leu Met Glu Gln Leu Leu Ala Leu Gln Gln Gln Gln 
225                 230                 235                 240 


Ile His Gln Leu Gln Leu Ile Glu Gln Ile Arg His Gln Ile Leu Leu 
                245                 250                 255     


Leu Ala Ser Gln Asn Ala Asp Leu Pro Thr Ser Ser Ser Pro Ser Gln 
            260                 265                 270         


Gly Thr Leu Arg Thr Ser Ala Asn Pro Leu Ser Thr Leu Ser Ser His 
        275                 280                 285             


Leu Ser Gln Gln Leu Ala Ala Ala Ala Gly Leu Ala Gln Ser Leu Ala 
    290                 295                 300                 


Ser Gln Ser Ala Ser Ile Ser Gly Val Lys Gln Leu Pro Pro Ile Gln 
305                 310                 315                 320 


Leu Pro Gln Ser Ser Ser Gly Asn Thr Ile Ile Pro Ser Asn Ser Gly 
                325                 330                 335     


Ser Ser Pro Asn Met Asn Ile Leu Ala Ala Ala Val Thr Thr Pro Ser 
            340                 345                 350         


Ser Glu Lys Val Ala Ser Ser Ala Gly Ala Ser His Val Ser Asn Pro 
        355                 360                 365             


Ala Val Ser Ser Ser Ser Ser Pro Ala Phe Ala Ile Ser Ser Leu Leu 
    370                 375                 380                 


Ser Pro Ala Ser Asn Pro Leu Leu Pro Gln Gln Ala Ser Ala Asn Ser 
385                 390                 395                 400 


Val Phe Pro Ser Pro Leu Pro Asn Ile Gly Thr Thr Ala Glu Asp Leu 
                405                 410                 415     


Asn Ser Leu Ser Ala Leu Ala Gln Gln Arg Lys Ser Lys Pro Pro Asn 
            420                 425                 430         


Val Thr Ala Phe Glu Ala Lys Ser Thr Ser Asp Glu Ala Phe Phe Lys 
        435                 440                 445             


His Lys Cys Arg Phe Cys Ala Lys Val Phe Gly Ser Asp Ser Ala Leu 
    450                 455                 460                 


Gln Ile His Leu Arg Ser His Thr Gly Glu Arg Pro Phe Lys Cys Asn 
465                 470                 475                 480 


Ile Cys Gly Asn Arg Phe Ser Thr Lys Gly Asn Leu Lys Val His Phe 
                485                 490                 495     


Gln Arg His Lys Glu Lys Tyr Pro His Ile Gln Met Asn Pro Tyr Pro 
            500                 505                 510         


Val Pro Glu His Leu Asp Asn Ile Pro Thr Ser Thr Gly Ile Pro Tyr 
        515                 520                 525             


Gly Met Ser Ile Pro Pro Glu Lys Pro Val Thr Ser Trp Leu Asp Thr 
    530                 535                 540                 


Lys Pro Val Leu Pro Thr Leu Thr Thr Ser Val Gly Leu Pro Leu Pro 
545                 550                 555                 560 


Pro Thr Leu Pro Ser Leu Ile Pro Phe Ile Lys Thr Glu Glu Pro Ala 
                565                 570                 575     


Pro Ile Pro Ile Ser His Ser Ala Thr Ser Pro Pro Gly Ser Val Lys 
            580                 585                 590         


Ser Asp Ser Gly Gly Pro Glu Ser Ala Thr Arg Asn Leu Gly Gly Leu 
        595                 600                 605             


Pro Glu Glu Ala Glu Gly Ser Thr Leu Pro Pro Ser Gly Gly Lys Ser 
    610                 615                 620                 


Glu Glu Ser Gly Met Val Thr Asn Ser Val Pro Thr Ala Ser Ser Ser 
625                 630                 635                 640 


Val Leu Ser Ser Pro Ala Ala Asp Cys Gly Pro Ala Gly Ser Ala Thr 
                645                 650                 655     


Thr Phe Thr Asn Pro Leu Leu Pro Leu Met Ser Glu Gln Phe Lys Ala 
            660                 665                 670         


Lys Phe Pro Phe Gly Gly Leu Leu Asp Ser Ala Gln Ala Ser Glu Thr 
        675                 680                 685             


Ser Lys Leu Gln Gln Leu Val Glu Asn Ile Asp Lys Lys Ala Thr Asp 
    690                 695                 700                 


Pro Asn Glu Cys Ile Ile Cys His Arg Val Leu Ser Cys Gln Ser Ala 
705                 710                 715                 720 


Leu Lys Met His Tyr Arg Thr His Thr Gly Glu Arg Pro Phe Lys Cys 
                725                 730                 735     


Lys Ile Cys Gly Arg Ala Phe Thr Thr Lys Gly Asn Leu Lys Thr His 
            740                 745                 750         


Tyr Ser Val His Arg Ala Met Pro Pro Leu Arg Val Gln His Ser Cys 
        755                 760                 765             


Pro Ile Cys Gln Lys Lys Phe Thr Asn Ala Val Val Leu Gln Gln His 
    770                 775                 780                 


Ile Arg Met His Met Gly Gly Gln Ile Pro Asn Thr Pro Val Pro Asp 
785                 790                 795                 800 


Ser Tyr Ser Glu Ser Met Glu Ser Asp Thr Gly Ser Phe Asp Glu Lys 
                805                 810                 815     


Asn Phe Asp Asp Leu Asp Asn Phe Ser Asp Glu Asn Met Glu Asp Cys 
            820                 825                 830         


Pro Glu Gly Ser Ile Pro Asp Thr Pro Lys Ser Ala Asp Ala Ser Gln 
        835                 840                 845             


Asp Ser Leu Ser Ser Ser Pro Leu Pro Leu Glu Met Ser Ser Ile Ala 
    850                 855                 860                 


Ala Leu Glu Asn Gln Met Lys Met Ile Asn Ala Gly Leu Ala Glu Gln 
865                 870                 875                 880 


Leu Gln Ala Ser Leu Lys Ser Val Glu Asn Gly Ser Ile Glu Gly Asp 
                885                 890                 895     


Val Leu Thr Asn Asp Ser Ser Ser Val Gly Gly Asp Met Glu Ser Gln 
            900                 905                 910         


Ser Ala Gly Ser Pro Ala Ile Ser Glu Ser Thr Ser Ser Met Gln Ala 
        915                 920                 925             


Leu Ser Pro Ser Asn Ser Thr Gln Glu Phe His Lys Ser Pro Ser Ile 
    930                 935                 940                 


Glu Glu Lys Pro Gln Arg Ala Val Pro Ser Glu Phe Ala Asn Gly Leu 
945                 950                 955                 960 


Ser Pro Thr Pro Val Asn Gly Gly Ala Leu Asp Leu Thr Ser Ser His 
                965                 970                 975     


Ala Glu Lys Ile Ile Lys Glu Asp Ser Leu Gly Ile Leu Phe Pro Phe 
            980                 985                 990         


Arg Asp Arg Gly Lys Phe Lys Asn  Thr Ala Cys Asp Ile  Cys Gly Lys 
        995                 1000                 1005             


Thr Phe  Ala Cys Gln Ser Ala  Leu Asp Ile His Tyr  Arg Ser His 
    1010                 1015                 1020             


Thr Lys  Glu Arg Pro Phe Ile  Cys Thr Val Cys Asn  Arg Gly Phe 
    1025                 1030                 1035             


Ser Thr  Lys Gly Asn Leu Lys  Gln His Met Leu Thr  His Gln Met 
    1040                 1045                 1050             


Arg Asp  Leu Pro Ser Gln Leu  Phe Glu Pro Ser Ser  Asn Leu Gly 
    1055                 1060                 1065             


Pro Asn  Gln Asn Ser Ala Val  Ile Pro Ala Asn Ser  Leu Ser Ser 
    1070                 1075                 1080             


Leu Ile  Lys Thr Glu Val Asn  Gly Phe Val His Val  Ser Pro Gln 
    1085                 1090                 1095             


Asp Ser  Lys Asp Thr Pro Thr  Ser His Val Pro Ser  Gly Pro Leu 
    1100                 1105                 1110             


Ser Ser  Ser Ala Thr Ser Pro  Val Leu Leu Pro Ala  Leu Pro Arg 
    1115                 1120                 1125             


Arg Thr  Pro Lys Gln His Tyr  Cys Asn Thr Cys Gly  Lys Thr Phe 
    1130                 1135                 1140             


Ser Ser  Ser Ser Ala Leu Gln  Ile His Glu Arg Thr  His Thr Gly 
    1145                 1150                 1155             


Glu Lys  Pro Phe Ala Cys Thr  Ile Cys Gly Arg Ala  Phe Thr Thr 
    1160                 1165                 1170             


Lys Gly  Asn Leu Lys Val His  Met Gly Thr His Met  Trp Asn Ser 
    1175                 1180                 1185             


Thr Pro  Ala Arg Arg Gly Arg  Arg Leu Ser Val Asp  Gly Pro Met 
    1190                 1195                 1200             


Thr Phe  Leu Gly Gly Asn Pro  Val Lys Phe Pro Glu  Met Phe Gln 
    1205                 1210                 1215             


Lys Asp  Leu Ala Ala Arg Ser  Gly Ser Gly Asp Pro  Ser Ser Phe 
    1220                 1225                 1230             


Trp Asn  Gln Tyr Ala Ala Ala  Leu Ser Asn Gly Leu  Ala Met Lys 
    1235                 1240                 1245             


Ala Asn  Glu Ile Ser Val Ile  Gln Asn Gly Gly Ile  Pro Pro Ile 
    1250                 1255                 1260             


Pro Gly  Ser Leu Gly Ser Gly  Asn Ser Ser Pro Val  Ser Gly Leu 
    1265                 1270                 1275             


Thr Gly  Asn Leu Glu Arg Leu  Gln Asn Ser Glu Pro  Asn Ala Pro 
    1280                 1285                 1290             


Leu Ala  Gly Leu Glu Lys Met  Ala Ser Ser Glu Asn  Gly Thr Asn 
    1295                 1300                 1305             


Phe Arg  Phe Thr Arg Phe Val  Glu Asp Ser Lys Glu  Ile Val Thr 
    1310                 1315                 1320             


Ser 
    


<210>  3436
<211>  1227
<212>  PRT
<213>  homo sapiens

<400>  3436

Met Asn Asp Thr Val Asn Lys Thr Asp Gln Val Asp Cys Ser Asp Leu 
1               5                   10                  15      


Ser Glu His Asn Gly Leu Asp Arg Glu Glu Ser Met Glu Val Glu Ala 
            20                  25                  30          


Pro Val Ala Asn Lys Ser Gly Ser Gly Thr Ser Ser Gly Ser His Ser 
        35                  40                  45              


Ser Thr Ala Pro Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Gly Gly 
    50                  55                  60                  


Gly Gly Ser Ser Ser Thr Gly Thr Ser Ala Ile Thr Thr Ser Leu Pro 
65                  70                  75                  80  


Gln Leu Gly Asp Leu Thr Thr Leu Gly Asn Phe Ser Val Ile Asn Ser 
                85                  90                  95      


Asn Val Ile Ile Glu Asn Leu Gln Ser Thr Lys Val Ala Val Ala Gln 
            100                 105                 110         


Phe Ser Gln Glu Ala Arg Cys Gly Gly Ala Ser Gly Gly Lys Leu Ala 
        115                 120                 125             


Val Pro Ala Leu Met Glu Gln Leu Leu Ala Leu Gln Gln Gln Gln Ile 
    130                 135                 140                 


His Gln Leu Gln Leu Ile Glu Gln Ile Arg His Gln Ile Leu Leu Leu 
145                 150                 155                 160 


Ala Ser Gln Asn Ala Asp Leu Pro Thr Ser Ser Ser Pro Ser Gln Gly 
                165                 170                 175     


Thr Leu Arg Thr Ser Ala Asn Pro Leu Ser Thr Leu Ser Ser His Leu 
            180                 185                 190         


Ser Gln Gln Leu Ala Ala Ala Ala Gly Leu Ala Gln Ser Leu Ala Ser 
        195                 200                 205             


Gln Ser Ala Ser Ile Ser Gly Val Lys Gln Leu Pro Pro Ile Gln Leu 
    210                 215                 220                 


Pro Gln Ser Ser Ser Gly Asn Thr Ile Ile Pro Ser Asn Ser Gly Ser 
225                 230                 235                 240 


Ser Pro Asn Met Asn Ile Leu Ala Ala Ala Val Thr Thr Pro Ser Ser 
                245                 250                 255     


Glu Lys Val Ala Ser Ser Ala Gly Ala Ser His Val Ser Asn Pro Ala 
            260                 265                 270         


Val Ser Ser Ser Ser Ser Pro Ala Phe Ala Ile Ser Ser Leu Leu Ser 
        275                 280                 285             


Pro Ala Ser Asn Pro Leu Leu Pro Gln Gln Ala Ser Ala Asn Ser Val 
    290                 295                 300                 


Phe Pro Ser Pro Leu Pro Asn Ile Gly Thr Thr Ala Glu Asp Leu Asn 
305                 310                 315                 320 


Ser Leu Ser Ala Leu Ala Gln Gln Arg Lys Ser Lys Pro Pro Asn Val 
                325                 330                 335     


Thr Ala Phe Glu Ala Lys Ser Thr Ser Asp Glu Ala Phe Phe Lys His 
            340                 345                 350         


Lys Cys Arg Phe Cys Ala Lys Val Phe Gly Ser Asp Ser Ala Leu Gln 
        355                 360                 365             


Ile His Leu Arg Ser His Thr Gly Glu Arg Pro Phe Lys Cys Asn Ile 
    370                 375                 380                 


Cys Gly Asn Arg Phe Ser Thr Lys Gly Asn Leu Lys Val His Phe Gln 
385                 390                 395                 400 


Arg His Lys Glu Lys Tyr Pro His Ile Gln Met Asn Pro Tyr Pro Val 
                405                 410                 415     


Pro Glu His Leu Asp Asn Ile Pro Thr Ser Thr Gly Ile Pro Tyr Gly 
            420                 425                 430         


Met Ser Ile Pro Pro Glu Lys Pro Val Thr Ser Trp Leu Asp Thr Lys 
        435                 440                 445             


Pro Val Leu Pro Thr Leu Thr Thr Ser Val Gly Leu Pro Leu Pro Pro 
    450                 455                 460                 


Thr Leu Pro Ser Leu Ile Pro Phe Ile Lys Thr Glu Glu Pro Ala Pro 
465                 470                 475                 480 


Ile Pro Ile Ser His Ser Ala Thr Ser Pro Pro Gly Ser Val Lys Ser 
                485                 490                 495     


Asp Ser Gly Gly Pro Glu Ser Ala Thr Arg Asn Leu Gly Gly Leu Pro 
            500                 505                 510         


Glu Glu Ala Glu Gly Ser Thr Leu Pro Pro Ser Gly Gly Lys Ser Glu 
        515                 520                 525             


Glu Ser Gly Met Val Thr Asn Ser Val Pro Thr Ala Ser Ser Ser Val 
    530                 535                 540                 


Leu Ser Ser Pro Ala Ala Asp Cys Gly Pro Ala Gly Ser Ala Thr Thr 
545                 550                 555                 560 


Phe Thr Asn Pro Leu Leu Pro Leu Met Ser Glu Gln Phe Lys Ala Lys 
                565                 570                 575     


Phe Pro Phe Gly Gly Leu Leu Asp Ser Ala Gln Ala Ser Glu Thr Ser 
            580                 585                 590         


Lys Leu Gln Gln Leu Val Glu Asn Ile Asp Lys Lys Ala Thr Asp Pro 
        595                 600                 605             


Asn Glu Cys Ile Ile Cys His Arg Val Leu Ser Cys Gln Ser Ala Leu 
    610                 615                 620                 


Lys Met His Tyr Arg Thr His Thr Gly Glu Arg Pro Phe Lys Cys Lys 
625                 630                 635                 640 


Ile Cys Gly Arg Ala Phe Thr Thr Lys Gly Asn Leu Lys Thr His Tyr 
                645                 650                 655     


Ser Val His Arg Ala Met Pro Pro Leu Arg Val Gln His Ser Cys Pro 
            660                 665                 670         


Ile Cys Gln Lys Lys Phe Thr Asn Ala Val Val Leu Gln Gln His Ile 
        675                 680                 685             


Arg Met His Met Gly Gly Gln Ile Pro Asn Thr Pro Val Pro Asp Ser 
    690                 695                 700                 


Tyr Ser Glu Ser Met Glu Ser Asp Thr Gly Ser Phe Asp Glu Lys Asn 
705                 710                 715                 720 


Phe Asp Asp Leu Asp Asn Phe Ser Asp Glu Asn Met Glu Asp Cys Pro 
                725                 730                 735     


Glu Gly Ser Ile Pro Asp Thr Pro Lys Ser Ala Asp Ala Ser Gln Asp 
            740                 745                 750         


Ser Leu Ser Ser Ser Pro Leu Pro Leu Glu Met Ser Ser Ile Ala Ala 
        755                 760                 765             


Leu Glu Asn Gln Met Lys Met Ile Asn Ala Gly Leu Ala Glu Gln Leu 
    770                 775                 780                 


Gln Ala Ser Leu Lys Ser Val Glu Asn Gly Ser Ile Glu Gly Asp Val 
785                 790                 795                 800 


Leu Thr Asn Asp Ser Ser Ser Val Gly Gly Asp Met Glu Ser Gln Ser 
                805                 810                 815     


Ala Gly Ser Pro Ala Ile Ser Glu Ser Thr Ser Ser Met Gln Ala Leu 
            820                 825                 830         


Ser Pro Ser Asn Ser Thr Gln Glu Phe His Lys Ser Pro Ser Ile Glu 
        835                 840                 845             


Glu Lys Pro Gln Arg Ala Val Pro Ser Glu Phe Ala Asn Gly Leu Ser 
    850                 855                 860                 


Pro Thr Pro Val Asn Gly Gly Ala Leu Asp Leu Thr Ser Ser His Ala 
865                 870                 875                 880 


Glu Lys Ile Ile Lys Glu Asp Ser Leu Gly Ile Leu Phe Pro Phe Arg 
                885                 890                 895     


Asp Arg Gly Lys Phe Lys Asn Thr Ala Cys Asp Ile Cys Gly Lys Thr 
            900                 905                 910         


Phe Ala Cys Gln Ser Ala Leu Asp Ile His Tyr Arg Ser His Thr Lys 
        915                 920                 925             


Glu Arg Pro Phe Ile Cys Thr Val Cys Asn Arg Gly Phe Ser Thr Lys 
    930                 935                 940                 


Gly Asn Leu Lys Gln His Met Leu Thr His Gln Met Arg Asp Leu Pro 
945                 950                 955                 960 


Ser Gln Leu Phe Glu Pro Ser Ser Asn Leu Gly Pro Asn Gln Asn Ser 
                965                 970                 975     


Ala Val Ile Pro Ala Asn Ser Leu Ser Ser Leu Ile Lys Thr Glu Val 
            980                 985                 990         


Asn Gly Phe Val His Val Ser Pro  Gln Asp Ser Lys Asp  Thr Pro Thr 
        995                 1000                 1005             


Ser His  Val Pro Ser Gly Pro  Leu Ser Ser Ser Ala  Thr Ser Pro 
    1010                 1015                 1020             


Val Leu  Leu Pro Ala Leu Pro  Arg Arg Thr Pro Lys  Gln His Tyr 
    1025                 1030                 1035             


Cys Asn  Thr Cys Gly Lys Thr  Phe Ser Ser Ser Ser  Ala Leu Gln 
    1040                 1045                 1050             


Ile His  Glu Arg Thr His Thr  Gly Glu Lys Pro Phe  Ala Cys Thr 
    1055                 1060                 1065             


Ile Cys  Gly Arg Ala Phe Thr  Thr Lys Gly Asn Leu  Lys Val His 
    1070                 1075                 1080             


Met Gly  Thr His Met Trp Asn  Ser Thr Pro Ala Arg  Arg Gly Arg 
    1085                 1090                 1095             


Arg Leu  Ser Val Asp Gly Pro  Met Thr Phe Leu Gly  Gly Asn Pro 
    1100                 1105                 1110             


Val Lys  Phe Pro Glu Met Phe  Gln Lys Asp Leu Ala  Ala Arg Ser 
    1115                 1120                 1125             


Gly Ser  Gly Asp Pro Ser Ser  Phe Trp Asn Gln Tyr  Ala Ala Ala 
    1130                 1135                 1140             


Leu Ser  Asn Gly Leu Ala Met  Lys Ala Asn Glu Ile  Ser Val Ile 
    1145                 1150                 1155             


Gln Asn  Gly Gly Ile Pro Pro  Ile Pro Gly Ser Leu  Gly Ser Gly 
    1160                 1165                 1170             


Asn Ser  Ser Pro Val Ser Gly  Leu Thr Gly Asn Leu  Glu Arg Leu 
    1175                 1180                 1185             


Gln Asn  Ser Glu Pro Asn Ala  Pro Leu Ala Gly Leu  Glu Lys Met 
    1190                 1195                 1200             


Ala Ser  Ser Glu Asn Gly Thr  Asn Phe Arg Phe Thr  Arg Phe Val 
    1205                 1210                 1215             


Glu Asp  Ser Lys Glu Ile Val  Thr Ser 
    1220                 1225         


<210>  3437
<211>  1300
<212>  PRT
<213>  homo sapiens

<400>  3437

Met Ser Arg Arg Lys Gln Ala Lys Pro Gln His Leu Lys Ser Asp Glu 
1               5                   10                  15      


Glu Leu Leu Pro Pro Asp Gly Ala Pro Glu His Ala Ala Pro Gly Glu 
            20                  25                  30          


Gly Ala Glu Asp Ala Asp Ser Gly Pro Glu Ser Arg Ser Gly Gly Glu 
        35                  40                  45              


Glu Thr Ser Val Cys Glu Lys Cys Cys Ala Glu Phe Phe Lys Trp Ala 
    50                  55                  60                  


Asp Phe Leu Glu His Gln Arg Ser Cys Thr Lys Leu Pro Pro Val Leu 
65                  70                  75                  80  


Ile Val His Glu Asp Ala Pro Ala Pro Pro Pro Glu Asp Phe Pro Glu 
                85                  90                  95      


Pro Ser Pro Ala Ser Ser Pro Ser Glu Arg Ala Glu Ser Glu Ala Ala 
            100                 105                 110         


Glu Glu Ala Gly Ala Glu Gly Ala Glu Gly Glu Ala Arg Pro Val Glu 
        115                 120                 125             


Lys Glu Ala Glu Pro Met Asp Ala Glu Pro Ala Gly Asp Thr Arg Ala 
    130                 135                 140                 


Pro Arg Pro Pro Pro Ala Ala Pro Ala Pro Pro Thr Pro Ala Tyr Gly 
145                 150                 155                 160 


Ala Pro Ser Thr Asn Val Thr Leu Glu Ala Leu Leu Ser Thr Lys Val 
                165                 170                 175     


Ala Val Ala Gln Phe Ser Gln Gly Ala Arg Ala Ala Gly Gly Ser Gly 
            180                 185                 190         


Ala Gly Gly Gly Val Ala Ala Ala Ala Val Pro Leu Ile Leu Glu Gln 
        195                 200                 205             


Leu Met Ala Leu Gln Gln Gln Gln Ile His Gln Leu Gln Leu Ile Glu 
    210                 215                 220                 


Gln Ile Arg Ser Gln Val Ala Leu Met Gln Arg Pro Pro Pro Arg Pro 
225                 230                 235                 240 


Ser Leu Ser Pro Ala Ala Ala Pro Ser Ala Pro Gly Pro Ala Pro Ser 
                245                 250                 255     


Gln Leu Pro Gly Leu Ala Ala Leu Pro Leu Ser Ala Gly Ala Pro Ala 
            260                 265                 270         


Ala Ala Ile Ala Gly Ser Gly Pro Ala Ala Pro Ala Ala Phe Glu Gly 
        275                 280                 285             


Ala Gln Pro Leu Ser Arg Pro Glu Ser Gly Ala Ser Thr Pro Gly Gly 
    290                 295                 300                 


Pro Ala Glu Pro Ser Ala Pro Ala Ala Pro Ser Ala Ala Pro Ala Pro 
305                 310                 315                 320 


Ala Ala Pro Ala Pro Ala Pro Ala Pro Gln Ser Ala Ala Ser Ser Gln 
                325                 330                 335     


Pro Gln Ser Ala Ser Thr Pro Pro Ala Leu Ala Pro Gly Ser Leu Leu 
            340                 345                 350         


Gly Ala Ala Pro Gly Leu Pro Ser Pro Leu Leu Pro Gln Thr Ser Ala 
        355                 360                 365             


Ser Gly Val Ile Phe Pro Asn Pro Leu Val Ser Ile Ala Ala Thr Ala 
    370                 375                 380                 


Asn Ala Leu Asp Pro Leu Ser Ala Leu Met Lys His Arg Lys Gly Lys 
385                 390                 395                 400 


Pro Pro Asn Val Ser Val Phe Glu Pro Lys Ala Ser Ala Glu Asp Pro 
                405                 410                 415     


Phe Phe Lys His Lys Cys Arg Phe Cys Ala Lys Val Phe Gly Ser Asp 
            420                 425                 430         


Ser Ala Leu Gln Ile His Leu Arg Ser His Thr Gly Glu Arg Pro Phe 
        435                 440                 445             


Lys Cys Asn Ile Cys Gly Asn Arg Phe Ser Thr Lys Gly Asn Leu Lys 
    450                 455                 460                 


Val His Phe Gln Arg His Lys Glu Lys Tyr Pro His Ile Gln Met Asn 
465                 470                 475                 480 


Pro Tyr Pro Val Pro Glu Tyr Leu Asp Asn Val Pro Thr Cys Ser Gly 
                485                 490                 495     


Ile Pro Tyr Gly Met Ser Leu Pro Pro Glu Lys Pro Val Thr Thr Trp 
            500                 505                 510         


Leu Asp Ser Lys Pro Val Leu Pro Thr Val Pro Thr Ser Val Gly Leu 
        515                 520                 525             


Gln Leu Pro Pro Thr Val Pro Gly Ala His Gly Tyr Ala Asp Ser Pro 
    530                 535                 540                 


Ser Ala Thr Pro Ala Ser Arg Ser Pro Gln Arg Pro Ser Pro Ala Ser 
545                 550                 555                 560 


Ser Glu Cys Ala Ser Leu Ser Pro Gly Leu Asn His Val Glu Ser Gly 
                565                 570                 575     


Val Ser Ala Thr Ala Glu Ser Pro Gln Ser Leu Leu Gly Gly Pro Pro 
            580                 585                 590         


Leu Thr Lys Ala Glu Pro Val Ser Leu Pro Cys Thr Asn Ala Arg Ala 
        595                 600                 605             


Gly Asp Ala Pro Val Gly Ala Gln Ala Ser Ala Ala Pro Thr Ser Val 
    610                 615                 620                 


Asp Gly Ala Pro Thr Ser Leu Gly Ser Pro Gly Leu Pro Ala Val Ser 
625                 630                 635                 640 


Glu Gln Phe Lys Ala Gln Phe Pro Phe Gly Gly Leu Leu Asp Ser Met 
                645                 650                 655     


Gln Thr Ser Glu Thr Ser Lys Leu Gln Gln Leu Val Glu Asn Ile Asp 
            660                 665                 670         


Lys Lys Met Thr Asp Pro Asn Gln Cys Val Ile Cys His Arg Val Leu 
        675                 680                 685             


Ser Cys Gln Ser Ala Leu Lys Met His Tyr Arg Thr His Thr Gly Glu 
    690                 695                 700                 


Arg Pro Phe Lys Cys Lys Ile Cys Gly Arg Ala Phe Thr Thr Lys Gly 
705                 710                 715                 720 


Asn Leu Lys Thr His Phe Gly Val His Arg Ala Lys Pro Pro Leu Arg 
                725                 730                 735     


Val Gln His Ser Cys Pro Ile Cys Gln Lys Lys Phe Thr Asn Ala Val 
            740                 745                 750         


Val Leu Gln Gln His Ile Arg Met His Met Gly Gly Gln Ile Pro Asn 
        755                 760                 765             


Thr Pro Leu Pro Glu Gly Phe Gln Asp Ala Met Asp Ser Glu Leu Ala 
    770                 775                 780                 


Tyr Asp Asp Lys Asn Ala Glu Thr Leu Ser Ser Tyr Asp Asp Asp Met 
785                 790                 795                 800 


Asp Glu Asn Ser Met Glu Asp Asp Ala Glu Leu Lys Asp Ala Ala Thr 
                805                 810                 815     


Asp Pro Ala Lys Pro Leu Leu Ser Tyr Ala Gly Ser Cys Pro Pro Ser 
            820                 825                 830         


Pro Pro Ser Val Ile Ser Ser Ile Ala Ala Leu Glu Asn Gln Met Lys 
        835                 840                 845             


Met Ile Asp Ser Val Met Ser Cys Gln Gln Leu Thr Gly Leu Lys Ser 
    850                 855                 860                 


Val Glu Asn Gly Ser Gly Glu Ser Asp Arg Leu Ser Asn Asp Ser Ser 
865                 870                 875                 880 


Ser Ala Val Gly Asp Leu Glu Ser Arg Ser Ala Gly Ser Pro Ala Leu 
                885                 890                 895     


Ser Glu Ser Ser Ser Ser Gln Ala Leu Ser Pro Ala Pro Ser Asn Gly 
            900                 905                 910         


Glu Ser Phe Arg Ser Lys Ser Pro Gly Leu Gly Ala Pro Glu Glu Pro 
        915                 920                 925             


Gln Glu Ile Pro Leu Lys Thr Glu Arg Pro Asp Ser Pro Ala Ala Ala 
    930                 935                 940                 


Pro Gly Ser Gly Gly Ala Pro Gly Arg Ala Gly Ile Lys Glu Glu Ala 
945                 950                 955                 960 


Pro Phe Ser Leu Leu Phe Leu Ser Arg Glu Arg Gly Lys Cys Pro Ser 
                965                 970                 975     


Thr Val Cys Gly Val Cys Gly Lys Pro Phe Ala Cys Lys Ser Ala Leu 
            980                 985                 990         


Glu Ile His Tyr Arg Ser His Thr  Lys Glu Arg Pro Phe  Val Cys Ala 
        995                 1000                 1005             


Leu Cys  Arg Arg Gly Cys Ser  Thr Met Gly Asn Leu  Lys Gln His 
    1010                 1015                 1020             


Leu Leu  Thr His Arg Leu Lys  Glu Leu Pro Ser Gln  Leu Phe Asp 
    1025                 1030                 1035             


Pro Asn  Phe Ala Leu Gly Pro  Ser Gln Ser Thr Pro  Ser Leu Ile 
    1040                 1045                 1050             


Ser Ser  Ala Ala Pro Thr Met  Ile Lys Met Glu Val  Asn Gly His 
    1055                 1060                 1065             


Gly Lys  Ala Met Ala Leu Gly  Glu Gly Pro Pro Leu  Pro Ala Gly 
    1070                 1075                 1080             


Val Gln  Val Pro Ala Gly Pro  Gln Thr Val Met Gly  Pro Gly Leu 
    1085                 1090                 1095             


Ala Pro  Met Leu Ala Pro Pro  Pro Arg Arg Thr Pro  Lys Gln His 
    1100                 1105                 1110             


Asn Cys  Gln Ser Cys Gly Lys  Thr Phe Ser Ser Ala  Ser Ala Leu 
    1115                 1120                 1125             


Gln Ile  His Glu Arg Thr His  Thr Gly Glu Lys Pro  Phe Gly Cys 
    1130                 1135                 1140             


Thr Ile  Cys Gly Arg Ala Phe  Thr Thr Lys Gly Asn  Leu Lys Val 
    1145                 1150                 1155             


His Met  Gly Thr His Met Trp  Asn Asn Ala Pro Ala  Arg Arg Gly 
    1160                 1165                 1170             


Arg Arg  Leu Ser Val Glu Asn  Pro Met Ala Leu Leu  Gly Gly Asp 
    1175                 1180                 1185             


Ala Leu  Lys Phe Ser Glu Met  Phe Gln Lys Asp Leu  Ala Ala Arg 
    1190                 1195                 1200             


Ala Met  Asn Val Asp Pro Ser  Phe Trp Asn Gln Tyr  Ala Ala Ala 
    1205                 1210                 1215             


Ile Thr  Asn Gly Leu Ala Met  Lys Asn Asn Glu Ile  Ser Val Ile 
    1220                 1225                 1230             


Gln Asn  Gly Gly Ile Pro Gln  Leu Pro Val Ser Leu  Gly Gly Ser 
    1235                 1240                 1245             


Ala Leu  Pro Pro Leu Gly Ser  Met Ala Ser Gly Met  Asp Lys Ala 
    1250                 1255                 1260             


Arg Thr  Gly Ser Ser Pro Pro  Ile Val Ser Leu Asp  Lys Ala Ser 
    1265                 1270                 1275             


Ser Glu  Thr Ala Ala Ser Arg  Pro Phe Thr Arg Phe  Ile Glu Asp 
    1280                 1285                 1290             


Asn Lys  Glu Ile Gly Ile Asn  
    1295                 1300 


<210>  3438
<211>  198
<212>  PRT
<213>  homo sapiens

<400>  3438

Met Ser Phe Ile Phe Glu Trp Ile Tyr Asn Gly Phe Ser Ser Val Leu 
1               5                   10                  15      


Gln Phe Leu Gly Leu Tyr Lys Lys Ser Gly Lys Leu Val Phe Leu Gly 
            20                  25                  30          


Leu Asp Asn Ala Gly Lys Thr Thr Leu Leu His Met Leu Lys Asp Asp 
        35                  40                  45              


Arg Leu Gly Gln His Val Pro Thr Leu His Pro Thr Ser Glu Glu Leu 
    50                  55                  60                  


Thr Ile Ala Gly Met Thr Phe Thr Thr Phe Asp Leu Gly Gly His Glu 
65                  70                  75                  80  


Gln Ala Arg Arg Val Trp Lys Asn Tyr Leu Pro Ala Ile Asn Gly Ile 
                85                  90                  95      


Val Phe Leu Val Asp Cys Ala Asp His Ser Arg Leu Val Glu Ser Lys 
            100                 105                 110         


Val Glu Leu Asn Ala Leu Met Thr Asp Glu Thr Ile Ser Asn Val Pro 
        115                 120                 125             


Ile Leu Ile Leu Gly Asn Lys Ile Asp Arg Thr Asp Ala Ile Ser Glu 
    130                 135                 140                 


Glu Lys Leu Arg Glu Ile Phe Gly Leu Tyr Gly Gln Thr Thr Gly Lys 
145                 150                 155                 160 


Gly Asn Val Thr Leu Lys Glu Leu Asn Ala Arg Pro Met Glu Val Phe 
                165                 170                 175     


Met Cys Ser Val Leu Lys Arg Gln Gly Tyr Gly Glu Gly Phe Arg Trp 
            180                 185                 190         


Leu Ser Gln Tyr Ile Asp 
        195             


<210>  3439
<211>  591
<212>  PRT
<213>  homo sapiens

<400>  3439

Met Phe Gly Ile Gln Glu Ser Ile Gln Arg Ser Gly Ser Ser Met Lys 
1               5                   10                  15      


Glu Glu Pro Leu Gly Ser Gly Met Asn Ala Val Arg Thr Trp Met Gln 
            20                  25                  30          


Gly Ala Gly Val Leu Asp Ala Asn Thr Ala Ala Gln Ser Gly Val Gly 
        35                  40                  45              


Leu Ala Arg Ala His Phe Glu Lys Gln Pro Pro Ser Asn Leu Arg Lys 
    50                  55                  60                  


Ser Asn Phe Phe His Phe Val Leu Ala Leu Tyr Asp Arg Gln Gly Gln 
65                  70                  75                  80  


Pro Val Glu Ile Glu Arg Thr Ala Phe Val Gly Phe Val Glu Lys Glu 
                85                  90                  95      


Lys Glu Ala Asn Ser Glu Lys Thr Asn Asn Gly Ile His Tyr Arg Leu 
            100                 105                 110         


Gln Leu Leu Tyr Ser Asn Gly Ile Arg Thr Glu Gln Asp Phe Tyr Val 
        115                 120                 125             


Arg Leu Ile Asp Ser Met Thr Lys Gln Ala Ile Val Tyr Glu Gly Gln 
    130                 135                 140                 


Asp Lys Asn Pro Glu Met Cys Arg Val Leu Leu Thr His Glu Ile Met 
145                 150                 155                 160 


Cys Ser Arg Cys Cys Asp Lys Lys Ser Cys Gly Asn Arg Asn Glu Thr 
                165                 170                 175     


Pro Ser Asp Pro Val Ile Ile Asp Arg Phe Phe Leu Lys Phe Phe Leu 
            180                 185                 190         


Lys Cys Asn Gln Asn Cys Leu Lys Asn Ala Gly Asn Pro Arg Asp Met 
        195                 200                 205             


Arg Arg Phe Gln Val Val Val Ser Thr Thr Val Asn Val Asp Gly His 
    210                 215                 220                 


Val Leu Ala Val Ser Asp Asn Met Phe Val His Asn Asn Ser Lys His 
225                 230                 235                 240 


Gly Arg Arg Ala Arg Arg Leu Asp Pro Ser Glu Gly Thr Pro Ser Tyr 
                245                 250                 255     


Leu Glu His Ala Thr Pro Cys Ile Lys Ala Ile Ser Pro Ser Glu Gly 
            260                 265                 270         


Trp Thr Thr Gly Gly Ala Thr Val Ile Ile Ile Gly Asp Asn Phe Phe 
        275                 280                 285             


Asp Gly Leu Gln Val Ile Phe Gly Thr Met Leu Val Trp Ser Glu Leu 
    290                 295                 300                 


Ile Thr Pro His Ala Ile Arg Val Gln Thr Pro Pro Arg His Ile Pro 
305                 310                 315                 320 


Gly Val Val Glu Val Thr Leu Ser Tyr Lys Ser Lys Gln Phe Cys Lys 
                325                 330                 335     


Gly Thr Pro Gly Arg Phe Ile Tyr Thr Ala Leu Asn Glu Pro Thr Ile 
            340                 345                 350         


Asp Tyr Gly Phe Gln Arg Leu Gln Lys Val Ile Pro Arg His Pro Gly 
        355                 360                 365             


Asp Pro Glu Arg Leu Pro Lys Glu Val Ile Leu Lys Arg Ala Ala Asp 
    370                 375                 380                 


Leu Val Glu Ala Leu Tyr Gly Met Pro His Asn Asn Gln Glu Ile Ile 
385                 390                 395                 400 


Leu Lys Arg Ala Ala Asp Ile Ala Glu Ala Leu Tyr Ser Val Pro Arg 
                405                 410                 415     


Asn His Asn Gln Leu Pro Ala Leu Ala Asn Thr Ser Val His Ala Gly 
            420                 425                 430         


Met Met Gly Val Asn Ser Phe Ser Gly Gln Leu Ala Val Asn Val Ser 
        435                 440                 445             


Glu Ala Ser Gln Ala Thr Asn Gln Gly Phe Thr Arg Asn Ser Ser Ser 
    450                 455                 460                 


Val Ser Pro His Gly Tyr Val Pro Ser Thr Thr Pro Gln Gln Thr Asn 
465                 470                 475                 480 


Tyr Asn Ser Val Thr Thr Ser Met Asn Gly Tyr Gly Ser Ala Ala Met 
                485                 490                 495     


Ser Asn Leu Gly Gly Ser Pro Thr Phe Leu Asn Gly Ser Ala Ala Asn 
            500                 505                 510         


Ser Pro Tyr Ala Ile Val Pro Ser Ser Pro Thr Met Ala Ser Ser Thr 
        515                 520                 525             


Ser Leu Pro Ser Asn Cys Ser Ser Ser Ser Gly Ile Phe Ser Phe Ser 
    530                 535                 540                 


Pro Ala Asn Met Val Ser Ala Val Lys Gln Lys Ser Ala Phe Ala Pro 
545                 550                 555                 560 


Val Val Arg Pro Gln Thr Ser Pro Pro Pro Thr Cys Thr Ser Thr Asn 
                565                 570                 575     


Gly Asn Ser Leu Gln Ala Ile Ser Gly Met Ile Val Pro Pro Met 
            580                 585                 590     


<210>  3440
<211>  158
<212>  PRT
<213>  homo sapiens

<400>  3440

Met Ala Ala Arg Ser Val Ser Gly Ile Thr Arg Arg Val Phe Met Trp 
1               5                   10                  15      


Thr Val Ser Gly Thr Pro Cys Arg Glu Phe Trp Ser Arg Phe Arg Lys 
            20                  25                  30          


Glu Lys Glu Pro Val Val Val Glu Thr Val Glu Glu Lys Lys Glu Pro 
        35                  40                  45              


Ile Leu Val Cys Pro Pro Leu Arg Ser Arg Ala Tyr Thr Pro Pro Glu 
    50                  55                  60                  


Asp Leu Gln Ser Arg Leu Glu Ser Tyr Val Lys Glu Val Phe Gly Ser 
65                  70                  75                  80  


Ser Leu Pro Ser Asn Trp Gln Asp Ile Ser Leu Glu Asp Ser Arg Leu 
                85                  90                  95      


Lys Phe Asn Leu Leu Ala His Leu Ala Asp Asp Leu Gly His Val Val 
            100                 105                 110         


Pro Asn Ser Arg Leu His Gln Met Cys Arg Val Arg Asp Val Leu Asp 
        115                 120                 125             


Phe Tyr Asn Val Pro Ile Gln Asp Arg Ser Lys Phe Asp Glu Leu Ser 
    130                 135                 140                 


Ala Ser Asn Leu Pro Pro Asn Leu Lys Ile Thr Trp Ser Tyr 
145                 150                 155             


<210>  3441
<211>  320
<212>  PRT
<213>  homo sapiens

<400>  3441

Met Glu Leu Cys Glu Phe Ala Phe Asn Met Lys Lys Asp Glu Val Cys 
1               5                   10                  15      


Val Asn Pro Tyr His Tyr Gln Arg Val Glu Thr Pro Val Leu Pro Pro 
            20                  25                  30          


Val Leu Val Pro Arg His Thr Glu Ile Pro Ala Glu Phe Pro Pro Leu 
        35                  40                  45              


Asp Asp Tyr Ser His Ser Ile Pro Glu Asn Thr Asn Phe Pro Ala Gly 
    50                  55                  60                  


Ile Glu Pro Gln Ser Asn Ile Pro Glu Thr Pro Pro Pro Gly Tyr Leu 
65                  70                  75                  80  


Ser Glu Asp Gly Glu Thr Ser Asp His Gln Met Asn His Ser Met Asp 
                85                  90                  95      


Ala Gly Ser Pro Asn Leu Ser Pro Asn Pro Met Ser Pro Ala His Asn 
            100                 105                 110         


Asn Leu Asp Leu Gln Pro Val Thr Tyr Cys Glu Pro Ala Phe Trp Cys 
        115                 120                 125             


Ser Ile Ser Tyr Tyr Glu Leu Asn Gln Arg Val Gly Glu Thr Phe His 
    130                 135                 140                 


Ala Ser Gln Pro Ser Met Thr Val Asp Gly Phe Thr Asp Pro Ser Asn 
145                 150                 155                 160 


Ser Glu Arg Phe Cys Leu Gly Leu Leu Ser Asn Val Asn Arg Asn Ala 
                165                 170                 175     


Ala Val Glu Leu Thr Arg Arg His Ile Gly Arg Gly Val Arg Leu Tyr 
            180                 185                 190         


Tyr Ile Gly Gly Glu Val Phe Ala Glu Cys Leu Ser Asp Ser Ala Ile 
        195                 200                 205             


Phe Val Gln Ser Pro Asn Cys Asn Gln Arg Tyr Gly Trp His Pro Ala 
    210                 215                 220                 


Thr Val Cys Lys Ile Pro Pro Gly Cys Asn Leu Lys Ile Phe Asn Asn 
225                 230                 235                 240 


Gln Glu Phe Ala Ala Leu Leu Ala Gln Ser Val Asn Gln Gly Phe Glu 
                245                 250                 255     


Ala Val Tyr Gln Leu Thr Arg Met Cys Thr Ile Arg Met Ser Phe Val 
            260                 265                 270         


Lys Gly Trp Gly Ala Glu Tyr Arg Arg Gln Thr Val Thr Ser Thr Pro 
        275                 280                 285             


Cys Trp Ile Glu Leu His Leu Asn Gly Pro Leu Gln Trp Leu Asp Lys 
    290                 295                 300                 


Val Leu Thr Gln Met Gly Ser Pro Ser Ile Arg Cys Ser Ser Val Ser 
305                 310                 315                 320 


<210>  3442
<211>  969
<212>  PRT
<213>  homo sapiens

<400>  3442

Met Ala Glu Asp Asp Pro Tyr Leu Gly Arg Pro Glu Gln Met Phe His 
1               5                   10                  15      


Leu Asp Pro Ser Leu Thr His Thr Ile Phe Asn Pro Glu Val Phe Gln 
            20                  25                  30          


Pro Gln Met Ala Leu Pro Thr Ala Asp Gly Pro Tyr Leu Gln Ile Leu 
        35                  40                  45              


Glu Gln Pro Lys Gln Arg Gly Phe Arg Phe Arg Tyr Val Cys Glu Gly 
    50                  55                  60                  


Pro Ser His Gly Gly Leu Pro Gly Ala Ser Ser Glu Lys Asn Lys Lys 
65                  70                  75                  80  


Ser Tyr Pro Gln Val Lys Ile Cys Asn Tyr Val Gly Pro Ala Lys Val 
                85                  90                  95      


Ile Val Gln Leu Val Thr Asn Gly Lys Asn Ile His Leu His Ala His 
            100                 105                 110         


Ser Leu Val Gly Lys His Cys Glu Asp Gly Ile Cys Thr Val Thr Ala 
        115                 120                 125             


Gly Pro Lys Asp Met Val Val Gly Phe Ala Asn Leu Gly Ile Leu His 
    130                 135                 140                 


Val Thr Lys Lys Lys Val Phe Glu Thr Leu Glu Ala Arg Met Thr Glu 
145                 150                 155                 160 


Ala Cys Ile Arg Gly Tyr Asn Pro Gly Leu Leu Val His Pro Asp Leu 
                165                 170                 175     


Ala Tyr Leu Gln Ala Glu Gly Gly Gly Asp Arg Gln Leu Gly Asp Arg 
            180                 185                 190         


Glu Lys Glu Leu Ile Arg Gln Ala Ala Leu Gln Gln Thr Lys Glu Met 
        195                 200                 205             


Asp Leu Ser Val Val Arg Leu Met Phe Thr Ala Phe Leu Pro Asp Ser 
    210                 215                 220                 


Thr Gly Ser Phe Thr Arg Arg Leu Glu Pro Val Val Ser Asp Ala Ile 
225                 230                 235                 240 


Tyr Asp Ser Lys Ala Pro Asn Ala Ser Asn Leu Lys Ile Val Arg Met 
                245                 250                 255     


Asp Arg Thr Ala Gly Cys Val Thr Gly Gly Glu Glu Ile Tyr Leu Leu 
            260                 265                 270         


Cys Asp Lys Val Gln Lys Asp Asp Ile Gln Ile Arg Phe Tyr Glu Glu 
        275                 280                 285             


Glu Glu Asn Gly Gly Val Trp Glu Gly Phe Gly Asp Phe Ser Pro Thr 
    290                 295                 300                 


Asp Val His Arg Gln Phe Ala Ile Val Phe Lys Thr Pro Lys Tyr Lys 
305                 310                 315                 320 


Asp Ile Asn Ile Thr Lys Pro Ala Ser Val Phe Val Gln Leu Arg Arg 
                325                 330                 335     


Lys Ser Asp Leu Glu Thr Ser Glu Pro Lys Pro Phe Leu Tyr Tyr Pro 
            340                 345                 350         


Glu Ile Lys Asp Lys Glu Glu Val Gln Arg Lys Arg Gln Lys Leu Met 
        355                 360                 365             


Pro Asn Phe Ser Asp Ser Phe Gly Gly Gly Ser Gly Ala Gly Ala Gly 
    370                 375                 380                 


Gly Gly Gly Met Phe Gly Ser Gly Gly Gly Gly Gly Gly Thr Gly Ser 
385                 390                 395                 400 


Thr Gly Pro Gly Tyr Ser Phe Pro His Tyr Gly Phe Pro Thr Tyr Gly 
                405                 410                 415     


Gly Ile Thr Phe His Pro Gly Thr Thr Lys Ser Asn Ala Gly Met Lys 
            420                 425                 430         


His Gly Thr Met Asp Thr Glu Ser Lys Lys Asp Pro Glu Gly Cys Asp 
        435                 440                 445             


Lys Ser Asp Asp Lys Asn Thr Val Asn Leu Phe Gly Lys Val Ile Glu 
    450                 455                 460                 


Thr Thr Glu Gln Asp Gln Glu Pro Ser Glu Ala Thr Val Gly Asn Gly 
465                 470                 475                 480 


Glu Val Thr Leu Thr Tyr Ala Thr Gly Thr Lys Glu Glu Ser Ala Gly 
                485                 490                 495     


Val Gln Asp Asn Leu Phe Leu Glu Lys Ala Met Gln Leu Ala Lys Arg 
            500                 505                 510         


His Ala Asn Ala Leu Phe Asp Tyr Ala Val Thr Gly Asp Val Lys Met 
        515                 520                 525             


Leu Leu Ala Val Gln Arg His Leu Thr Ala Val Gln Asp Glu Asn Gly 
    530                 535                 540                 


Asp Ser Val Leu His Leu Ala Ile Ile His Leu His Ser Gln Leu Val 
545                 550                 555                 560 


Arg Asp Leu Leu Glu Val Thr Ser Gly Leu Ile Ser Asp Asp Ile Ile 
                565                 570                 575     


Asn Met Arg Asn Asp Leu Tyr Gln Thr Pro Leu His Leu Ala Val Ile 
            580                 585                 590         


Thr Lys Gln Glu Asp Val Val Glu Asp Leu Leu Arg Ala Gly Ala Asp 
        595                 600                 605             


Leu Ser Leu Leu Asp Arg Leu Gly Asn Ser Val Leu His Leu Ala Ala 
    610                 615                 620                 


Lys Glu Gly His Asp Lys Val Leu Ser Ile Leu Leu Lys His Lys Lys 
625                 630                 635                 640 


Ala Ala Leu Leu Leu Asp His Pro Asn Gly Asp Gly Leu Asn Ala Ile 
                645                 650                 655     


His Leu Ala Met Met Ser Asn Ser Leu Pro Cys Leu Leu Leu Leu Val 
            660                 665                 670         


Ala Ala Gly Ala Asp Val Asn Ala Gln Glu Gln Lys Ser Gly Arg Thr 
        675                 680                 685             


Ala Leu His Leu Ala Val Glu His Asp Asn Ile Ser Leu Ala Gly Cys 
    690                 695                 700                 


Leu Leu Leu Glu Gly Asp Ala His Val Asp Ser Thr Thr Tyr Asp Gly 
705                 710                 715                 720 


Thr Thr Pro Leu His Ile Ala Ala Gly Arg Gly Ser Thr Arg Leu Ala 
                725                 730                 735     


Ala Leu Leu Lys Ala Ala Gly Ala Asp Pro Leu Val Glu Asn Phe Glu 
            740                 745                 750         


Pro Leu Tyr Asp Leu Asp Asp Ser Trp Glu Asn Ala Gly Glu Asp Glu 
        755                 760                 765             


Gly Val Val Pro Gly Thr Thr Pro Leu Asp Met Ala Thr Ser Trp Gln 
    770                 775                 780                 


Val Phe Asp Ile Leu Asn Gly Lys Pro Tyr Glu Pro Glu Phe Thr Ser 
785                 790                 795                 800 


Asp Asp Leu Leu Ala Gln Gly Asp Met Lys Gln Leu Ala Glu Asp Val 
                805                 810                 815     


Lys Leu Gln Leu Tyr Lys Leu Leu Glu Ile Pro Asp Pro Asp Lys Asn 
            820                 825                 830         


Trp Ala Thr Leu Ala Gln Lys Leu Gly Leu Gly Ile Leu Asn Asn Ala 
        835                 840                 845             


Phe Arg Leu Ser Pro Ala Pro Ser Lys Thr Leu Met Asp Asn Tyr Glu 
    850                 855                 860                 


Val Ser Gly Gly Thr Val Arg Glu Leu Val Glu Ala Leu Arg Gln Met 
865                 870                 875                 880 


Gly Tyr Thr Glu Ala Ile Glu Val Ile Gln Ala Ala Ser Ser Pro Val 
                885                 890                 895     


Lys Thr Thr Ser Gln Ala His Ser Leu Pro Leu Ser Pro Ala Ser Thr 
            900                 905                 910         


Arg Gln Gln Ile Asp Glu Leu Arg Asp Ser Asp Ser Val Cys Asp Ser 
        915                 920                 925             


Gly Val Glu Thr Ser Phe Arg Lys Leu Ser Phe Thr Glu Ser Leu Thr 
    930                 935                 940                 


Ser Gly Ala Ser Leu Leu Thr Leu Asn Lys Met Pro His Asp Tyr Gly 
945                 950                 955                 960 


Gln Glu Gly Pro Leu Glu Gly Lys Ile 
                965                 


<210>  3443
<211>  1268
<212>  PRT
<213>  homo sapiens

<400>  3443

Met Ile Ala Ala Pro Glu Ile Pro Thr Asp Phe Asn Leu Leu Gln Glu 
1               5                   10                  15      


Ser Glu Thr His Phe Ser Ser Asp Thr Asp Phe Glu Asp Ile Glu Gly 
            20                  25                  30          


Lys Asn Gln Lys Gln Gly Lys Gly Lys Thr Cys Lys Lys Gly Lys Lys 
        35                  40                  45              


Gly Pro Ala Glu Lys Gly Lys Gly Gly Asn Gly Gly Gly Lys Pro Pro 
    50                  55                  60                  


Ser Gly Pro Asn Arg Met Asn Gly His His Gln Gln Asn Gly Val Glu 
65                  70                  75                  80  


Asn Met Met Leu Phe Glu Val Val Lys Met Gly Lys Ser Ala Met Gln 
                85                  90                  95      


Ser Val Val Asp Asp Trp Ile Glu Ser Tyr Lys His Asp Arg Asp Ile 
            100                 105                 110         


Ala Leu Leu Asp Leu Ile Asn Phe Phe Ile Gln Cys Ser Gly Cys Lys 
        115                 120                 125             


Gly Val Val Thr Ala Glu Met Phe Arg His Met Gln Asn Ser Glu Ile 
    130                 135                 140                 


Ile Arg Lys Met Thr Glu Glu Phe Asp Glu Asp Ser Gly Asp Tyr Pro 
145                 150                 155                 160 


Leu Thr Met Ala Gly Pro Gln Trp Lys Lys Phe Lys Ser Ser Phe Cys 
                165                 170                 175     


Glu Phe Ile Gly Val Leu Val Arg Gln Cys Gln Tyr Ser Ile Ile Tyr 
            180                 185                 190         


Asp Glu Tyr Met Met Asp Thr Val Ile Ser Leu Leu Thr Gly Leu Ser 
        195                 200                 205             


Asp Ser Gln Val Arg Ala Phe Arg His Thr Ser Thr Leu Ala Ala Met 
    210                 215                 220                 


Lys Leu Met Thr Ala Leu Val Asn Val Ala Leu Asn Leu Ser Ile Asn 
225                 230                 235                 240 


Met Asp Asn Thr Gln Arg Gln Tyr Glu Ala Glu Arg Asn Lys Met Ile 
                245                 250                 255     


Gly Lys Arg Ala Asn Glu Arg Leu Glu Leu Leu Leu Gln Lys Arg Lys 
            260                 265                 270         


Glu Leu Gln Glu Asn Gln Asp Glu Ile Glu Asn Met Met Asn Ala Ile 
        275                 280                 285             


Phe Lys Gly Val Phe Val His Arg Tyr Arg Asp Ala Ile Ala Glu Ile 
    290                 295                 300                 


Arg Ala Ile Cys Ile Glu Glu Ile Gly Ile Trp Met Lys Met Tyr Ser 
305                 310                 315                 320 


Asp Ala Phe Leu Asn Asp Ser Tyr Leu Lys Tyr Val Gly Trp Thr Met 
                325                 330                 335     


His Asp Lys Gln Gly Glu Val Arg Leu Lys Cys Leu Thr Ala Leu Gln 
            340                 345                 350         


Gly Leu Tyr Tyr Asn Lys Glu Leu Asn Ser Lys Leu Glu Leu Phe Thr 
        355                 360                 365             


Ser Arg Phe Lys Asp Arg Ile Val Ser Met Thr Leu Asp Lys Glu Tyr 
    370                 375                 380                 


Asp Val Ala Val Gln Ala Ile Lys Leu Leu Thr Leu Val Leu Gln Ser 
385                 390                 395                 400 


Ser Glu Glu Val Leu Thr Ala Glu Asp Cys Glu Asn Val Tyr His Leu 
                405                 410                 415     


Val Tyr Ser Ala His Arg Pro Val Ala Val Ala Ala Gly Glu Phe Leu 
            420                 425                 430         


Tyr Lys Lys Leu Phe Ser Arg Arg Asp Pro Glu Glu Asp Gly Met Met 
        435                 440                 445             


Lys Arg Arg Gly Arg Gln Gly Pro Asn Ala Asn Leu Val Lys Thr Leu 
    450                 455                 460                 


Val Phe Phe Phe Leu Glu Ser Glu Leu His Glu His Ala Ala Tyr Leu 
465                 470                 475                 480 


Val Asp Ser Met Trp Asp Cys Ala Thr Glu Leu Leu Lys Asp Trp Glu 
                485                 490                 495     


Cys Met Asn Ser Leu Leu Leu Glu Glu Pro Leu Ser Gly Glu Glu Ala 
            500                 505                 510         


Leu Thr Asp Arg Gln Glu Ser Ala Leu Ile Glu Ile Met Leu Cys Thr 
        515                 520                 525             


Ile Arg Gln Ala Ala Glu Cys His Pro Pro Val Gly Arg Gly Thr Gly 
    530                 535                 540                 


Lys Arg Val Leu Thr Ala Lys Glu Lys Lys Thr Gln Leu Asp Asp Arg 
545                 550                 555                 560 


Thr Lys Ile Thr Glu Leu Phe Ala Val Ala Leu Pro Gln Leu Leu Ala 
                565                 570                 575     


Lys Tyr Ser Val Asp Ala Glu Lys Val Thr Asn Leu Leu Gln Leu Pro 
            580                 585                 590         


Gln Tyr Phe Asp Leu Glu Ile Tyr Thr Thr Gly Arg Leu Glu Lys His 
        595                 600                 605             


Leu Asp Ala Leu Leu Arg Gln Ile Arg Asn Ile Val Glu Lys His Thr 
    610                 615                 620                 


Asp Thr Asp Val Leu Glu Ala Cys Ser Lys Thr Tyr His Ala Leu Cys 
625                 630                 635                 640 


Asn Glu Glu Phe Thr Ile Phe Asn Arg Val Asp Ile Ser Arg Ser Gln 
                645                 650                 655     


Leu Ile Asp Glu Leu Ala Asp Lys Phe Asn Arg Leu Leu Glu Asp Phe 
            660                 665                 670         


Leu Gln Glu Gly Glu Glu Pro Asp Glu Asp Asp Ala Tyr Gln Val Leu 
        675                 680                 685             


Ser Thr Leu Lys Arg Ile Thr Ala Phe His Asn Ala His Asp Leu Ser 
    690                 695                 700                 


Lys Trp Asp Leu Phe Ala Cys Asn Tyr Lys Leu Leu Lys Thr Gly Ile 
705                 710                 715                 720 


Glu Asn Gly Asp Met Pro Glu Gln Ile Val Ile His Ala Leu Gln Cys 
                725                 730                 735     


Thr His Tyr Val Ile Leu Trp Gln Leu Ala Lys Ile Thr Glu Ser Ser 
            740                 745                 750         


Ser Thr Lys Glu Asp Leu Leu Arg Leu Lys Lys Gln Met Arg Val Phe 
        755                 760                 765             


Cys Gln Ile Cys Gln His Tyr Leu Thr Asn Val Asn Thr Thr Val Lys 
    770                 775                 780                 


Glu Gln Ala Phe Thr Ile Leu Cys Asp Ile Leu Met Ile Phe Ser His 
785                 790                 795                 800 


Gln Ile Met Ser Gly Gly Arg Asp Met Leu Glu Pro Leu Val Tyr Thr 
                805                 810                 815     


Pro Asp Ser Ser Leu Gln Ser Glu Leu Leu Ser Phe Ile Leu Asp His 
            820                 825                 830         


Val Phe Ile Glu Gln Asp Asp Asp Asn Asn Ser Ala Asp Gly Gln Gln 
        835                 840                 845             


Glu Asp Glu Ala Ser Lys Ile Glu Ala Leu His Lys Arg Arg Asn Leu 
    850                 855                 860                 


Leu Ala Ala Phe Cys Lys Leu Ile Val Tyr Thr Val Val Glu Met Asn 
865                 870                 875                 880 


Thr Ala Ala Asp Ile Phe Lys Gln Tyr Met Lys Tyr Tyr Asn Asp Tyr 
                885                 890                 895     


Gly Asp Ile Ile Lys Glu Thr Met Ser Lys Thr Arg Gln Ile Asp Lys 
            900                 905                 910         


Ile Gln Cys Ala Lys Thr Leu Ile Leu Ser Leu Gln Gln Leu Phe Asn 
        915                 920                 925             


Glu Met Ile Gln Glu Asn Gly Tyr Asn Phe Asp Arg Ser Ser Ser Thr 
    930                 935                 940                 


Phe Ser Gly Ile Lys Glu Leu Ala Arg Arg Phe Ala Leu Thr Phe Gly 
945                 950                 955                 960 


Leu Asp Gln Leu Lys Thr Arg Glu Ala Ile Ala Met Leu His Lys Asp 
                965                 970                 975     


Gly Ile Glu Phe Ala Phe Lys Glu Pro Asn Pro Gln Gly Glu Ser His 
            980                 985                 990         


Pro Pro Leu Asn Leu Ala Phe Leu  Asp Ile Leu Ser Glu  Phe Ser Ser 
        995                 1000                 1005             


Lys Leu  Leu Arg Gln Asp Lys  Arg Thr Val Tyr Val  Tyr Leu Glu 
    1010                 1015                 1020             


Lys Phe  Met Thr Phe Gln Met  Ser Leu Arg Arg Glu  Asp Val Trp 
    1025                 1030                 1035             


Leu Pro  Leu Met Ser Tyr Arg  Asn Ser Leu Leu Ala  Gly Gly Asp 
    1040                 1045                 1050             


Asp Asp  Thr Met Ser Val Ile  Ser Gly Ile Ser Ser  Arg Gly Ser 
    1055                 1060                 1065             


Thr Val  Arg Ser Lys Lys Ser  Lys Pro Ser Thr Gly  Lys Arg Lys 
    1070                 1075                 1080             


Val Val  Glu Gly Met Gln Leu  Ser Leu Thr Glu Glu  Ser Ser Ser 
    1085                 1090                 1095             


Ser Asp  Ser Met Trp Leu Ser  Arg Glu Gln Thr Leu  His Thr Pro 
    1100                 1105                 1110             


Val Met  Met Gln Thr Pro Gln  Leu Thr Ser Thr Ile  Met Arg Glu 
    1115                 1120                 1125             


Pro Lys  Arg Leu Arg Pro Glu  Asp Ser Phe Met Ser  Val Tyr Pro 
    1130                 1135                 1140             


Met Gln  Thr Glu His His Gln  Thr Pro Leu Asp Tyr  Asn Thr Gln 
    1145                 1150                 1155             


Val Thr  Trp Met Leu Ala Gln  Arg Gln Gln Glu Glu  Ala Arg Gln 
    1160                 1165                 1170             


Gln Gln  Glu Arg Ala Ala Met  Ser Tyr Val Lys Leu  Arg Thr Asn 
    1175                 1180                 1185             


Leu Gln  His Ala Ile Arg Arg  Gly Thr Ser Leu Met  Glu Asp Asp 
    1190                 1195                 1200             


Glu Glu  Pro Ile Val Glu Asp  Val Met Met Ser Ser  Glu Gly Arg 
    1205                 1210                 1215             


Ile Glu  Asp Leu Asn Glu Gly  Met Asp Phe Asp Thr  Met Asp Ile 
    1220                 1225                 1230             


Asp Leu  Pro Pro Ser Lys Asn  Arg Arg Glu Arg Thr  Glu Leu Lys 
    1235                 1240                 1245             


Pro Asp  Phe Phe Asp Pro Ala  Ser Ile Met Asp Glu  Ser Val Leu 
    1250                 1255                 1260             


Gly Val  Ser Met Phe 
    1265             


<210>  3444
<211>  1231
<212>  PRT
<213>  homo sapiens

<400>  3444

Met Ile Ala Ala Pro Glu Ile Pro Thr Asp Phe Asn Leu Leu Gln Glu 
1               5                   10                  15      


Ser Glu Thr His Phe Ser Ser Asp Thr Asp Phe Glu Asp Ile Glu Gly 
            20                  25                  30          


Lys Asn Gln Lys Gln Gly Lys Gly Lys Thr Cys Lys Lys Gly Lys Lys 
        35                  40                  45              


Gly Pro Ala Glu Lys Gly Lys Gly Gly Asn Gly Gly Gly Lys Pro Pro 
    50                  55                  60                  


Ser Gly Pro Asn Arg Met Asn Gly His His Gln Gln Asn Gly Val Glu 
65                  70                  75                  80  


Asn Met Met Leu Phe Glu Val Val Lys Met Gly Lys Ser Ala Met Gln 
                85                  90                  95      


Ser Val Val Asp Asp Trp Ile Glu Ser Tyr Lys His Asp Arg Asp Ile 
            100                 105                 110         


Ala Leu Leu Asp Leu Ile Asn Phe Phe Ile Gln Cys Ser Gly Cys Lys 
        115                 120                 125             


Gly Val Val Thr Ala Glu Met Phe Arg His Met Gln Asn Ser Glu Ile 
    130                 135                 140                 


Ile Arg Lys Met Thr Glu Glu Phe Asp Glu Asp Ser Gly Asp Tyr Pro 
145                 150                 155                 160 


Leu Thr Met Ala Gly Pro Gln Trp Lys Lys Phe Lys Ser Ser Phe Cys 
                165                 170                 175     


Glu Phe Ile Gly Val Leu Val Arg Gln Cys Gln Tyr Ser Ile Ile Tyr 
            180                 185                 190         


Asp Glu Tyr Met Met Asp Thr Val Ile Ser Leu Leu Thr Gly Leu Ser 
        195                 200                 205             


Asp Ser Gln Val Arg Ala Phe Arg His Thr Ser Thr Leu Ala Ala Met 
    210                 215                 220                 


Lys Leu Met Thr Ala Leu Val Asn Val Ala Leu Asn Leu Ser Ile Asn 
225                 230                 235                 240 


Met Asp Asn Thr Gln Arg Gln Tyr Glu Ala Glu Arg Asn Lys Met Ile 
                245                 250                 255     


Gly Lys Arg Ala Asn Glu Arg Leu Glu Leu Leu Leu Gln Lys Arg Lys 
            260                 265                 270         


Glu Leu Gln Glu Asn Gln Asp Glu Ile Glu Asn Met Met Asn Ala Ile 
        275                 280                 285             


Phe Lys Gly Val Phe Val His Arg Tyr Arg Asp Ala Ile Ala Glu Ile 
    290                 295                 300                 


Arg Ala Ile Cys Ile Glu Glu Ile Gly Ile Trp Met Lys Met Tyr Ser 
305                 310                 315                 320 


Asp Ala Phe Leu Asn Asp Ser Tyr Leu Lys Tyr Val Gly Trp Thr Met 
                325                 330                 335     


His Asp Lys Gln Gly Glu Val Arg Leu Lys Cys Leu Thr Ala Leu Gln 
            340                 345                 350         


Gly Leu Tyr Tyr Asn Lys Glu Leu Asn Ser Lys Leu Glu Leu Phe Thr 
        355                 360                 365             


Ser Arg Phe Lys Asp Arg Ile Val Ser Met Thr Leu Asp Lys Glu Tyr 
    370                 375                 380                 


Asp Val Ala Val Gln Ala Ile Lys Leu Leu Thr Leu Val Leu Gln Ser 
385                 390                 395                 400 


Ser Glu Glu Val Leu Thr Ala Glu Asp Cys Glu Asn Val Tyr His Leu 
                405                 410                 415     


Val Tyr Ser Ala His Arg Pro Val Ala Val Ala Ala Gly Glu Phe Leu 
            420                 425                 430         


Tyr Lys Lys Leu Phe Ser Arg Arg Asp Pro Glu Glu Asp Gly Met Met 
        435                 440                 445             


Lys Arg Arg Gly Arg Gln Gly Pro Asn Ala Asn Leu Val Lys Thr Leu 
    450                 455                 460                 


Val Phe Phe Phe Leu Glu Ser Glu Leu His Glu His Ala Ala Tyr Leu 
465                 470                 475                 480 


Val Asp Ser Met Trp Asp Cys Ala Thr Glu Leu Leu Lys Asp Trp Glu 
                485                 490                 495     


Cys Met Asn Ser Leu Leu Leu Glu Glu Pro Leu Ser Gly Glu Glu Ala 
            500                 505                 510         


Leu Thr Asp Arg Gln Glu Ser Ala Leu Ile Glu Ile Met Leu Cys Thr 
        515                 520                 525             


Ile Arg Gln Ala Ala Glu Cys His Pro Pro Val Gly Arg Gly Thr Gly 
    530                 535                 540                 


Lys Arg Val Leu Thr Ala Lys Glu Lys Lys Thr Gln Leu Asp Asp Arg 
545                 550                 555                 560 


Thr Lys Ile Thr Glu Leu Phe Ala Val Ala Leu Pro Gln Leu Leu Ala 
                565                 570                 575     


Lys Tyr Ser Val Asp Ala Glu Lys Val Thr Asn Leu Leu Gln Leu Pro 
            580                 585                 590         


Gln Tyr Phe Asp Leu Glu Ile Tyr Thr Thr Gly Arg Leu Glu Lys His 
        595                 600                 605             


Leu Asp Ala Leu Leu Arg Gln Ile Arg Asn Ile Val Glu Lys His Thr 
    610                 615                 620                 


Asp Thr Asp Val Leu Glu Ala Cys Ser Lys Thr Tyr His Ala Leu Cys 
625                 630                 635                 640 


Asn Glu Glu Phe Thr Ile Phe Asn Arg Val Asp Ile Ser Arg Ser Gln 
                645                 650                 655     


Leu Ile Asp Glu Leu Ala Asp Lys Phe Asn Arg Leu Leu Glu Asp Phe 
            660                 665                 670         


Leu Gln Glu Gly Glu Glu Pro Asp Glu Asp Asp Ala Tyr Gln Val Leu 
        675                 680                 685             


Ser Thr Leu Lys Arg Ile Thr Ala Phe His Asn Ala His Asp Leu Ser 
    690                 695                 700                 


Lys Trp Asp Leu Phe Ala Cys Asn Tyr Lys Leu Leu Lys Thr Gly Ile 
705                 710                 715                 720 


Glu Asn Gly Asp Met Pro Glu Gln Ile Val Ile His Ala Leu Gln Cys 
                725                 730                 735     


Thr His Tyr Val Ile Leu Trp Gln Leu Ala Lys Ile Thr Glu Ser Ser 
            740                 745                 750         


Ser Thr Lys Glu Asp Leu Leu Arg Leu Lys Lys Gln Met Arg Val Phe 
        755                 760                 765             


Cys Gln Ile Cys Gln His Tyr Leu Thr Asn Val Asn Thr Thr Val Lys 
    770                 775                 780                 


Glu Gln Ala Phe Thr Ile Leu Cys Asp Ile Leu Met Ile Phe Ser His 
785                 790                 795                 800 


Gln Ile Met Ser Gly Gly Arg Asp Met Leu Glu Pro Leu Val Tyr Thr 
                805                 810                 815     


Pro Asp Ser Ser Leu Gln Ser Glu Leu Leu Ser Phe Ile Leu Asp His 
            820                 825                 830         


Val Phe Ile Glu Gln Asp Asp Asp Asn Asn Ser Ala Asp Gly Gln Gln 
        835                 840                 845             


Glu Asp Glu Ala Ser Lys Ile Glu Ala Leu His Lys Arg Arg Asn Leu 
    850                 855                 860                 


Leu Ala Ala Phe Cys Lys Leu Ile Val Tyr Thr Val Val Glu Met Asn 
865                 870                 875                 880 


Thr Ala Ala Asp Ile Phe Lys Gln Tyr Met Lys Tyr Tyr Asn Asp Tyr 
                885                 890                 895     


Gly Asp Ile Ile Lys Glu Thr Met Ser Lys Thr Arg Gln Ile Asp Lys 
            900                 905                 910         


Ile Gln Cys Ala Lys Thr Leu Ile Leu Ser Leu Gln Gln Leu Phe Asn 
        915                 920                 925             


Glu Met Ile Gln Glu Asn Gly Tyr Asn Phe Asp Arg Ser Ser Ser Thr 
    930                 935                 940                 


Phe Ser Gly Ile Lys Glu Leu Ala Arg Arg Phe Ala Leu Thr Phe Gly 
945                 950                 955                 960 


Leu Asp Gln Leu Lys Thr Arg Glu Ala Ile Ala Met Leu His Lys Asp 
                965                 970                 975     


Gly Ile Glu Phe Ala Phe Lys Glu Pro Asn Pro Gln Gly Glu Ser His 
            980                 985                 990         


Pro Pro Leu Asn Leu Ala Phe Leu  Asp Ile Leu Ser Glu  Phe Ser Ser 
        995                 1000                 1005             


Lys Leu  Leu Arg Gln Asp Lys  Arg Thr Val Tyr Val  Tyr Leu Glu 
    1010                 1015                 1020             


Lys Phe  Met Thr Phe Gln Met  Ser Leu Arg Arg Glu  Asp Val Trp 
    1025                 1030                 1035             


Leu Pro  Leu Met Ser Tyr Arg  Asn Ser Leu Leu Ala  Gly Gly Asp 
    1040                 1045                 1050             


Asp Asp  Thr Met Ser Val Ile  Ser Gly Ile Ser Ser  Arg Gly Ser 
    1055                 1060                 1065             


Thr Val  Arg Ser Lys Lys Ser  Lys Pro Ser Thr Gly  Lys Arg Lys 
    1070                 1075                 1080             


Val Val  Glu Gly Met Gln Leu  Ser Leu Thr Glu Glu  Ser Ser Ser 
    1085                 1090                 1095             


Ser Asp  Ser Met Trp Leu Ser  Arg Glu Gln Thr Leu  His Thr Pro 
    1100                 1105                 1110             


Val Met  Met Gln Thr Pro Gln  Leu Thr Ser Thr Ile  Met Arg Glu 
    1115                 1120                 1125             


Pro Lys  Arg Leu Arg Pro Glu  Asp Ser Phe Met Ser  Val Tyr Pro 
    1130                 1135                 1140             


Met Gln  Thr Glu His His Gln  Thr Pro Leu Asp Tyr  Asn Arg Arg 
    1145                 1150                 1155             


Gly Thr  Ser Leu Met Glu Asp  Asp Glu Glu Pro Ile  Val Glu Asp 
    1160                 1165                 1170             


Val Met  Met Ser Ser Glu Gly  Arg Ile Glu Asp Leu  Asn Glu Gly 
    1175                 1180                 1185             


Met Asp  Phe Asp Thr Met Asp  Ile Asp Leu Pro Pro  Ser Lys Asn 
    1190                 1195                 1200             


Arg Arg  Glu Arg Thr Glu Leu  Lys Pro Asp Phe Phe  Asp Pro Ala 
    1205                 1210                 1215             


Ser Ile  Met Asp Glu Ser Val  Leu Gly Val Ser Met  Phe 
    1220                 1225                 1230     


<210>  3445
<211>  1151
<212>  PRT
<213>  homo sapiens

<400>  3445

Met Pro Cys Gly Phe Ser Pro Ser Pro Val Ala His His Leu Val Pro 
1               5                   10                  15      


Gly Pro Pro Asp Thr Pro Ala Gln Gln Leu Arg Cys Gly Trp Thr Val 
            20                  25                  30          


Gly Gly Trp Leu Leu Ser Leu Val Arg Gly Leu Leu Pro Cys Leu Pro 
        35                  40                  45              


Pro Gly Ala Arg Thr Ala Glu Gly Pro Ile Met Val Leu Ala Gly Pro 
    50                  55                  60                  


Leu Ala Val Ser Leu Leu Leu Pro Ser Leu Thr Leu Leu Val Ser His 
65                  70                  75                  80  


Leu Ser Ser Ser Gln Asp Val Ser Ser Glu Pro Ser Ser Glu Gln Gln 
                85                  90                  95      


Leu Cys Ala Leu Ser Lys His Pro Thr Val Ala Phe Glu Asp Leu Gln 
            100                 105                 110         


Pro Trp Val Ser Asn Phe Thr Tyr Pro Gly Ala Arg Asp Phe Ser Gln 
        115                 120                 125             


Leu Ala Leu Asp Pro Ser Gly Asn Gln Leu Ile Val Gly Ala Arg Asn 
    130                 135                 140                 


Tyr Leu Phe Arg Leu Ser Leu Ala Asn Val Ser Leu Leu Gln Ala Thr 
145                 150                 155                 160 


Glu Trp Ala Ser Ser Glu Asp Thr Arg Arg Ser Cys Gln Ser Lys Gly 
                165                 170                 175     


Lys Thr Glu Glu Glu Cys Gln Asn Tyr Val Arg Val Leu Ile Val Ala 
            180                 185                 190         


Gly Arg Lys Val Phe Met Cys Gly Thr Asn Ala Phe Ser Pro Met Cys 
        195                 200                 205             


Thr Ser Arg Gln Val Gly Asn Leu Ser Arg Thr Ile Glu Lys Ile Asn 
    210                 215                 220                 


Gly Val Ala Arg Cys Pro Tyr Asp Pro Arg His Asn Ser Thr Ala Val 
225                 230                 235                 240 


Ile Ser Ser Gln Gly Glu Leu Tyr Ala Ala Thr Val Ile Asp Phe Ser 
                245                 250                 255     


Gly Arg Asp Pro Ala Ile Tyr Arg Ser Leu Gly Ser Gly Pro Pro Leu 
            260                 265                 270         


Arg Thr Ala Gln Tyr Asn Ser Lys Trp Leu Asn Glu Pro Asn Phe Val 
        275                 280                 285             


Ala Ala Tyr Asp Ile Gly Leu Phe Ala Tyr Phe Phe Leu Arg Glu Asn 
    290                 295                 300                 


Ala Val Glu His Asp Cys Gly Arg Thr Val Tyr Ser Arg Val Ala Arg 
305                 310                 315                 320 


Val Cys Lys Asn Asp Val Gly Gly Arg Phe Leu Leu Glu Asp Thr Trp 
                325                 330                 335     


Thr Thr Phe Met Lys Ala Arg Leu Asn Cys Ser Arg Pro Gly Glu Val 
            340                 345                 350         


Pro Phe Tyr Tyr Asn Glu Leu Gln Ser Ala Phe His Leu Pro Glu Gln 
        355                 360                 365             


Asp Leu Ile Tyr Gly Val Phe Thr Thr Asn Val Asn Ser Ile Ala Ala 
    370                 375                 380                 


Ser Ala Val Cys Ala Phe Asn Leu Ser Ala Ile Ser Gln Ala Phe Asn 
385                 390                 395                 400 


Gly Pro Phe Arg Tyr Gln Glu Asn Pro Arg Ala Ala Trp Leu Pro Ile 
                405                 410                 415     


Ala Asn Pro Ile Pro Asn Phe Gln Cys Gly Thr Leu Pro Glu Thr Gly 
            420                 425                 430         


Pro Asn Glu Asn Leu Thr Glu Arg Ser Leu Gln Asp Ala Gln Arg Leu 
        435                 440                 445             


Phe Leu Met Ser Glu Ala Val Gln Pro Val Thr Pro Glu Pro Cys Val 
    450                 455                 460                 


Thr Gln Asp Ser Val Arg Phe Ser His Leu Val Val Asp Leu Val Gln 
465                 470                 475                 480 


Ala Lys Asp Thr Leu Tyr His Val Leu Tyr Ile Gly Thr Glu Ser Gly 
                485                 490                 495     


Thr Ile Leu Lys Ala Leu Ser Thr Ala Ser Arg Ser Leu His Gly Cys 
            500                 505                 510         


Tyr Leu Glu Glu Leu His Val Leu Pro Pro Gly Arg Arg Glu Pro Leu 
        515                 520                 525             


Arg Ser Leu Arg Ile Leu His Ser Ala Arg Ala Leu Phe Val Gly Leu 
    530                 535                 540                 


Arg Asp Gly Val Leu Arg Val Pro Leu Glu Arg Cys Ala Ala Tyr Arg 
545                 550                 555                 560 


Ser Gln Gly Ala Cys Leu Gly Ala Arg Asp Pro Tyr Cys Gly Trp Asp 
                565                 570                 575     


Gly Lys Gln Gln Arg Cys Ser Thr Leu Glu Asp Ser Ser Asn Met Ser 
            580                 585                 590         


Leu Trp Thr Gln Asn Ile Thr Ala Cys Pro Val Arg Asn Val Thr Arg 
        595                 600                 605             


Asp Gly Gly Phe Gly Pro Trp Ser Pro Trp Gln Pro Cys Glu His Leu 
    610                 615                 620                 


Asp Gly Asp Asn Ser Gly Ser Cys Leu Cys Arg Ala Arg Ser Cys Asp 
625                 630                 635                 640 


Ser Pro Arg Pro Arg Cys Gly Gly Leu Asp Cys Leu Gly Pro Ala Ile 
                645                 650                 655     


His Ile Ala Asn Cys Ser Arg Asn Gly Ala Trp Thr Pro Trp Ser Ser 
            660                 665                 670         


Trp Ala Leu Cys Ser Thr Ser Cys Gly Ile Gly Phe Gln Val Arg Gln 
        675                 680                 685             


Arg Ser Cys Ser Asn Pro Ala Pro Arg His Gly Gly Arg Ile Cys Val 
    690                 695                 700                 


Gly Lys Ser Arg Glu Glu Arg Phe Cys Asn Glu Asn Thr Pro Cys Pro 
705                 710                 715                 720 


Val Pro Ile Phe Trp Ala Ser Trp Gly Ser Trp Ser Lys Cys Ser Ser 
                725                 730                 735     


Asn Cys Gly Gly Gly Met Gln Ser Arg Arg Arg Ala Cys Glu Asn Gly 
            740                 745                 750         


Asn Ser Cys Leu Gly Cys Gly Val Glu Phe Lys Thr Cys Asn Pro Glu 
        755                 760                 765             


Gly Cys Pro Glu Val Arg Arg Asn Thr Pro Trp Thr Pro Trp Leu Pro 
    770                 775                 780                 


Val Asn Val Thr Gln Gly Gly Ala Arg Gln Glu Gln Arg Phe Arg Phe 
785                 790                 795                 800 


Thr Cys Arg Ala Pro Leu Ala Asp Pro His Gly Leu Gln Phe Gly Arg 
                805                 810                 815     


Arg Arg Thr Glu Thr Arg Thr Cys Pro Ala Asp Gly Ser Gly Ser Cys 
            820                 825                 830         


Asp Thr Asp Ala Leu Val Glu Val Leu Leu Arg Ser Gly Ser Thr Ser 
        835                 840                 845             


Pro His Thr Val Ser Gly Gly Trp Ala Ala Trp Gly Pro Trp Ser Ser 
    850                 855                 860                 


Cys Ser Arg Asp Cys Glu Leu Gly Phe Arg Val Arg Lys Arg Thr Cys 
865                 870                 875                 880 


Thr Asn Pro Glu Pro Arg Asn Gly Gly Leu Pro Cys Val Gly Asp Ala 
                885                 890                 895     


Ala Glu Tyr Gln Asp Cys Asn Pro Gln Ala Cys Pro Val Arg Gly Ala 
            900                 905                 910         


Trp Ser Cys Trp Thr Ser Trp Ser Pro Cys Ser Ala Ser Cys Gly Gly 
        915                 920                 925             


Gly His Tyr Gln Arg Thr Arg Ser Cys Thr Ser Pro Ala Pro Ser Pro 
    930                 935                 940                 


Gly Glu Asp Ile Cys Leu Gly Leu His Thr Glu Glu Ala Leu Cys Ala 
945                 950                 955                 960 


Thr Gln Ala Cys Pro Glu Gly Trp Ser Pro Trp Ser Glu Trp Ser Lys 
                965                 970                 975     


Cys Thr Asp Asp Gly Ala Gln Ser Arg Ser Arg His Cys Glu Glu Leu 
            980                 985                 990         


Leu Pro Gly Ser Ser Ala Cys Ala  Gly Asn Ser Ser Gln  Ser Arg Pro 
        995                 1000                 1005             


Cys Pro  Tyr Ser Glu Ile Pro  Val Ile Leu Pro Ala  Ser Ser Met 
    1010                 1015                 1020             


Glu Glu  Ala Thr Asp Cys Ala  Gly Phe Asn Leu Ile  His Leu Val 
    1025                 1030                 1035             


Ala Thr  Gly Ile Ser Cys Phe  Leu Gly Ser Gly Leu  Leu Thr Leu 
    1040                 1045                 1050             


Ala Val  Tyr Leu Ser Cys Gln  His Cys Gln Arg Gln  Ser Gln Glu 
    1055                 1060                 1065             


Ser Thr  Leu Val His Pro Ala  Thr Pro Asn His Leu  His Tyr Lys 
    1070                 1075                 1080             


Gly Gly  Gly Thr Pro Lys Asn  Glu Lys Tyr Thr Pro  Met Glu Phe 
    1085                 1090                 1095             


Lys Thr  Leu Asn Lys Asn Asn  Leu Ile Pro Asp Asp  Arg Ala Asn 
    1100                 1105                 1110             


Phe Tyr  Pro Leu Gln Gln Thr  Asn Val Tyr Thr Thr  Thr Tyr Tyr 
    1115                 1120                 1125             


Pro Ser  Pro Leu Asn Lys His  Ser Phe Arg Pro Glu  Ala Ser Pro 
    1130                 1135                 1140             


Gly Gln  Arg Cys Phe Pro Asn  Ser 
    1145                 1150     


<210>  3446
<211>  398
<212>  PRT
<213>  homo sapiens

<400>  3446

Met Lys Ala Leu Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser 
1               5                   10                  15      


Pro Gln Asn Gly Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala 
            20                  25                  30          


Asn Lys Ser Glu Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn 
        35                  40                  45              


Met Pro Val Ser Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met 
    50                  55                  60                  


Lys Ser Phe Val Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly 
65                  70                  75                  80  


Glu Gly Asn Ser Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val 
                85                  90                  95      


Leu Gln Glu Leu Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro 
            100                 105                 110         


Lys Leu Phe Phe Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro 
        115                 120                 125             


Glu Tyr Gly Gln Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln 
    130                 135                 140                 


Gln Ala Lys Lys Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg 
145                 150                 155                 160 


Gly Met Pro Arg Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn 
                165                 170                 175     


Glu Val Ala Thr Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn 
            180                 185                 190         


Ala Ala Glu Ala Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn 
        195                 200                 205             


Leu Gln Asp Gln Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly 
    210                 215                 220                 


Pro Lys Pro Gly Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile 
225                 230                 235                 240 


Leu His Leu Ser Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His 
                245                 250                 255     


Lys Val Ile Ser Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met 
            260                 265                 270         


Asn Gln Pro Ser Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser 
        275                 280                 285             


Ser Ala Thr Ile Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr 
    290                 295                 300                 


Ala Glu Ala Ile Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser 
305                 310                 315                 320 


Pro Val Gln Pro Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly 
                325                 330                 335     


Phe Gln Ala Ala Leu Ser Ala Leu Lys Gln Phe Ser Glu Gln Gly Leu 
            340                 345                 350         


Asp Pro Ile Asp Gly Ala Met Asn Ile Glu Lys Gly Ser Leu Glu Lys 
        355                 360                 365             


Gln Ala Lys His Leu Arg Glu Lys Ala Asp Asn Asn Gln Ala Pro Pro 
    370                 375                 380                 


Gly Ser Ile Ala Gln Asp Cys Lys Lys Ser Asn Ser Ala Val 
385                 390                 395             


<210>  3447
<211>  479
<212>  PRT
<213>  homo sapiens

<400>  3447

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15      


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30          


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45              


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60                  


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80  


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95      


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
            100                 105                 110         


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
        115                 120                 125             


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
    130                 135                 140                 


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
145                 150                 155                 160 


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
                165                 170                 175     


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
            180                 185                 190         


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
        195                 200                 205             


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
    210                 215                 220                 


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
225                 230                 235                 240 


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
                245                 250                 255     


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
            260                 265                 270         


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
        275                 280                 285             


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
    290                 295                 300                 


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
305                 310                 315                 320 


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
                325                 330                 335     


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
            340                 345                 350         


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
        355                 360                 365             


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
    370                 375                 380                 


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
385                 390                 395                 400 


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
                405                 410                 415     


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
            420                 425                 430         


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
        435                 440                 445             


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
    450                 455                 460                 


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Val 
465                 470                 475                 


<210>  3448
<211>  473
<212>  PRT
<213>  homo sapiens

<400>  3448

Met Phe Ser Val Gln Leu Ser Leu Gly Glu Gln Thr Trp Glu Ser Glu 
1               5                   10                  15      


Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala Val Ala Asn Lys Ala Leu 
            20                  25                  30          


Thr Glu Ser Thr Leu Pro Lys Pro Val Gln Lys Pro Pro Lys Ser Asn 
        35                  40                  45              


Val Asn Asn Asn Pro Gly Ser Ile Thr Pro Thr Val Glu Leu Asn Gly 
    50                  55                  60                  


Leu Ala Met Lys Arg Gly Glu Pro Ala Ile Tyr Arg Pro Leu Asp Pro 
65                  70                  75                  80  


Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr Asn Phe Arg Gly Met Tyr 
                85                  90                  95      


Asn Gln Arg Tyr His Cys Pro Val Pro Lys Ile Phe Tyr Val Gln Leu 
            100                 105                 110         


Thr Val Gly Asn Asn Glu Phe Phe Gly Glu Gly Lys Thr Arg Gln Ala 
        115                 120                 125             


Ala Arg His Asn Ala Ala Met Lys Ala Leu Gln Ala Leu Gln Asn Glu 
    130                 135                 140                 


Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly Glu Ser Gly Lys Asp Val 
145                 150                 155                 160 


Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu Ile Ser Leu Val Phe Glu 
                165                 170                 175     


Ile Ala Leu Lys Arg Asn Met Pro Val Ser Phe Glu Val Ile Lys Glu 
            180                 185                 190         


Ser Gly Pro Pro His Met Lys Ser Phe Val Thr Arg Val Ser Val Gly 
        195                 200                 205             


Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser Lys Lys Leu Ser Lys Lys 
    210                 215                 220                 


Arg Ala Ala Thr Thr Val Leu Gln Glu Leu Lys Lys Leu Pro Pro Leu 
225                 230                 235                 240 


Pro Val Val Glu Lys Pro Lys Leu Phe Phe Lys Lys Arg Pro Lys Thr 
                245                 250                 255     


Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln Gly Met Asn Pro Ile Ser 
            260                 265                 270         


Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys Glu Lys Glu Pro Asp Tyr 
        275                 280                 285             


Val Leu Leu Ser Glu Arg Gly Met Pro Arg Arg Arg Glu Phe Val Met 
    290                 295                 300                 


Gln Val Lys Val Gly Asn Glu Val Ala Thr Gly Thr Gly Pro Asn Lys 
305                 310                 315                 320 


Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala Met Leu Leu Gln Leu Gly 
                325                 330                 335     


Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln Leu Glu Lys Thr Gly Glu 
            340                 345                 350         


Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly Phe Pro Glu Pro Thr Asn 
        355                 360                 365             


Asn Thr Pro Lys Gly Ile Leu His Leu Ser Pro Asp Val Tyr Gln Glu 
    370                 375                 380                 


Met Glu Ala Ser Arg His Lys Val Ile Ser Gly Thr Thr Leu Gly Tyr 
385                 390                 395                 400 


Leu Ser Pro Lys Asp Met Asn Gln Pro Ser Ser Ser Phe Phe Ser Ile 
                405                 410                 415     


Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile Ala Arg Glu Leu Leu Met 
            420                 425                 430         


Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile Gly Leu Lys Gly Ser Ser 
        435                 440                 445             


Pro Thr Pro Pro Cys Ser Pro Val Gln Pro Ser Lys Gln Leu Glu Tyr 
    450                 455                 460                 


Leu Ala Arg Ile Gln Gly Phe Gln Val 
465                 470             


<210>  3449
<211>  1353
<212>  PRT
<213>  homo sapiens

<400>  3449

Met Leu Asp Pro Ser Ser Ser Glu Glu Glu Ser Asp Glu Ile Val Glu 
1               5                   10                  15      


Glu Glu Ser Gly Lys Glu Val Leu Gly Ser Ala Pro Ser Gly Ala Arg 
            20                  25                  30          


Leu Ser Pro Ser Arg Thr Ser Glu Gly Ser Ala Gly Ser Ala Gly Leu 
        35                  40                  45              


Gly Gly Gly Gly Ala Gly Ala Gly Ala Gly Val Gly Ala Gly Gly Gly 
    50                  55                  60                  


Gly Gly Ser Gly Ala Ser Ser Gly Gly Gly Ala Gly Gly Leu Gln Pro 
65                  70                  75                  80  


Ser Ser Arg Ala Gly Gly Gly Arg Pro Ser Ser Pro Ser Pro Ser Val 
                85                  90                  95      


Val Ser Glu Lys Glu Lys Glu Glu Leu Glu Arg Leu Gln Lys Glu Glu 
            100                 105                 110         


Glu Glu Arg Lys Lys Arg Leu Gln Leu Tyr Val Phe Val Met Arg Cys 
        115                 120                 125             


Ile Ala Tyr Pro Phe Asn Ala Lys Gln Pro Thr Asp Met Ala Arg Arg 
    130                 135                 140                 


Gln Gln Lys Ile Ser Lys Gln Gln Leu Gln Thr Val Lys Asp Arg Phe 
145                 150                 155                 160 


Gln Ala Phe Leu Asn Gly Glu Thr Gln Ile Met Ala Asp Glu Ala Phe 
                165                 170                 175     


Met Asn Ala Val Gln Ser Tyr Tyr Glu Val Phe Leu Lys Ser Asp Arg 
            180                 185                 190         


Val Ala Arg Met Val Gln Ser Gly Gly Cys Ser Ala Asn Asp Ser Arg 
        195                 200                 205             


Glu Val Phe Lys Lys His Ile Glu Lys Arg Val Arg Ser Leu Pro Glu 
    210                 215                 220                 


Ile Asp Gly Leu Ser Lys Glu Thr Val Leu Ser Ser Trp Met Ala Lys 
225                 230                 235                 240 


Phe Asp Ala Ile Tyr Arg Gly Glu Glu Asp Pro Arg Lys Gln Gln Ala 
                245                 250                 255     


Arg Met Thr Ala Ser Ala Ala Ser Glu Leu Ile Leu Ser Lys Glu Gln 
            260                 265                 270         


Leu Tyr Glu Met Phe Gln Asn Ile Leu Gly Ile Lys Lys Phe Glu His 
        275                 280                 285             


Gln Leu Leu Tyr Asn Ala Cys Gln Leu Asp Asn Pro Asp Glu Gln Ala 
    290                 295                 300                 


Ala Gln Ile Arg Arg Glu Leu Asp Gly Arg Leu Gln Met Ala Asp Gln 
305                 310                 315                 320 


Ile Ala Arg Glu Arg Lys Phe Pro Lys Phe Val Ser Lys Glu Met Glu 
                325                 330                 335     


Asn Met Tyr Ile Glu Glu Leu Lys Ser Ser Val Asn Leu Leu Met Ala 
            340                 345                 350         


Asn Leu Glu Ser Met Pro Val Ser Lys Gly Gly Glu Phe Lys Leu Gln 
        355                 360                 365             


Lys Leu Lys Arg Ser His Asn Ala Ser Ile Ile Asp Met Gly Glu Glu 
    370                 375                 380                 


Ser Glu Asn Gln Leu Ser Lys Ser Asp Val Val Leu Ser Phe Ser Leu 
385                 390                 395                 400 


Glu Val Val Ile Met Glu Val Gln Gly Leu Lys Ser Leu Ala Pro Asn 
                405                 410                 415     


Arg Ile Val Tyr Cys Thr Met Glu Val Glu Gly Gly Glu Lys Leu Gln 
            420                 425                 430         


Thr Asp Gln Ala Glu Ala Ser Lys Pro Thr Trp Gly Thr Gln Gly Asp 
        435                 440                 445             


Phe Ser Thr Thr His Ala Leu Pro Ala Val Lys Val Lys Leu Phe Thr 
    450                 455                 460                 


Glu Ser Thr Gly Val Leu Ala Leu Glu Asp Lys Glu Leu Gly Arg Val 
465                 470                 475                 480 


Ile Leu His Pro Thr Pro Asn Ser Pro Lys Gln Ser Glu Trp His Lys 
                485                 490                 495     


Met Thr Val Ser Lys Asn Cys Pro Asp Gln Asp Leu Lys Ile Lys Leu 
            500                 505                 510         


Ala Val Arg Met Asp Lys Pro Gln Asn Met Lys His Ser Gly Tyr Leu 
        515                 520                 525             


Trp Ala Ile Gly Lys Asn Val Trp Lys Arg Trp Lys Lys Arg Phe Phe 
    530                 535                 540                 


Val Leu Val Gln Val Ser Gln Tyr Thr Phe Ala Met Cys Ser Tyr Arg 
545                 550                 555                 560 


Glu Lys Lys Ala Glu Pro Gln Glu Leu Leu Gln Leu Asp Gly Tyr Thr 
                565                 570                 575     


Val Asp Tyr Thr Asp Pro Gln Pro Gly Leu Glu Gly Gly Arg Ala Phe 
            580                 585                 590         


Phe Asn Ala Val Lys Glu Gly Asp Thr Val Ile Phe Ala Ser Asp Asp 
        595                 600                 605             


Glu Gln Asp Arg Ile Leu Trp Val Gln Ala Met Tyr Arg Ala Thr Gly 
    610                 615                 620                 


Gln Ser His Lys Pro Val Pro Pro Thr Gln Val Gln Lys Leu Asn Ala 
625                 630                 635                 640 


Lys Gly Gly Asn Val Pro Gln Leu Asp Ala Pro Ile Ser Gln Phe Tyr 
                645                 650                 655     


Ala Asp Arg Ala Gln Lys His Gly Met Asp Glu Phe Ile Ser Ser Asn 
            660                 665                 670         


Pro Cys Asn Phe Asp His Ala Ser Leu Phe Glu Met Val Gln Arg Leu 
        675                 680                 685             


Thr Leu Asp His Arg Leu Asn Asp Ser Tyr Ser Cys Leu Gly Trp Phe 
    690                 695                 700                 


Ser Pro Gly Gln Val Phe Val Leu Asp Glu Tyr Cys Ala Arg Asn Gly 
705                 710                 715                 720 


Val Arg Gly Cys His Arg His Leu Cys Tyr Leu Arg Asp Leu Leu Glu 
                725                 730                 735     


Arg Ala Glu Asn Gly Ala Met Ile Asp Pro Thr Leu Leu His Tyr Ser 
            740                 745                 750         


Phe Ala Phe Cys Ala Ser His Val His Gly Asn Arg Pro Asp Gly Ile 
        755                 760                 765             


Gly Thr Val Thr Val Glu Glu Lys Glu Arg Phe Glu Glu Ile Lys Glu 
    770                 775                 780                 


Arg Leu Arg Val Leu Leu Glu Asn Gln Ile Thr His Phe Arg Tyr Cys 
785                 790                 795                 800 


Phe Pro Phe Gly Arg Pro Glu Gly Ala Leu Lys Ala Thr Leu Ser Leu 
                805                 810                 815     


Leu Glu Arg Val Leu Met Lys Asp Ile Val Thr Pro Val Pro Gln Glu 
            820                 825                 830         


Glu Val Lys Thr Val Ile Arg Lys Cys Leu Glu Gln Ala Ala Leu Val 
        835                 840                 845             


Asn Tyr Ser Arg Leu Ser Glu Tyr Ala Lys Ile Glu Glu Asn Gln Lys 
    850                 855                 860                 


Asp Ala Glu Asn Val Gly Arg Leu Ile Thr Pro Ala Lys Lys Leu Glu 
865                 870                 875                 880 


Asp Thr Ile Arg Leu Ala Glu Leu Val Ile Glu Val Leu Gln Gln Asn 
                885                 890                 895     


Glu Glu His His Ala Glu Pro His Val Asp Lys Gly Glu Ala Phe Ala 
            900                 905                 910         


Trp Trp Ser Asp Leu Met Val Glu His Ala Glu Thr Phe Leu Ser Leu 
        915                 920                 925             


Phe Ala Val Asp Met Asp Ala Ala Leu Glu Val Gln Pro Pro Asp Thr 
    930                 935                 940                 


Trp Asp Ser Phe Pro Leu Phe Gln Leu Leu Asn Asp Phe Leu Arg Thr 
945                 950                 955                 960 


Asp Tyr Asn Leu Cys Asn Gly Lys Phe His Lys His Leu Gln Asp Leu 
                965                 970                 975     


Phe Ala Pro Leu Val Val Arg Tyr Val Asp Leu Met Glu Ser Ser Ile 
            980                 985                 990         


Ala Gln Ser Ile His Arg Gly Phe  Glu Arg Glu Ser Trp  Glu Pro Val 
        995                 1000                 1005             


Lys Ser  Leu Thr Ser Asn Leu  Pro Asn Val Asn Leu  Pro Asn Val 
    1010                 1015                 1020             


Asn Leu  Pro Lys Val Pro Asn  Leu Pro Val Asn Ile  Pro Leu Gly 
    1025                 1030                 1035             


Ile Pro  Gln Met Pro Thr Phe  Ser Ala Pro Ser Trp  Met Ala Ala 
    1040                 1045                 1050             


Ile Tyr  Asp Ala Asp Asn Gly  Ser Gly Thr Ser Glu  Asp Leu Phe 
    1055                 1060                 1065             


Trp Lys  Leu Asp Ala Leu Gln  Thr Phe Ile Arg Asp  Leu His Trp 
    1070                 1075                 1080             


Pro Glu  Glu Glu Phe Gly Lys  His Leu Glu Gln Arg  Leu Lys Leu 
    1085                 1090                 1095             


Met Ala  Ser Asp Met Ile Glu  Ser Cys Val Lys Arg  Thr Arg Ile 
    1100                 1105                 1110             


Ala Phe  Glu Val Lys Leu Gln  Lys Thr Ser Arg Ser  Thr Asp Phe 
    1115                 1120                 1125             


Arg Val  Pro Gln Ser Ile Cys  Thr Met Phe Asn Val  Met Val Asp 
    1130                 1135                 1140             


Ala Lys  Ala Gln Ser Thr Lys  Leu Cys Ser Met Glu  Met Gly Gln 
    1145                 1150                 1155             


Glu His  Gln Tyr His Ser Lys  Ile Asp Glu Leu Ile  Glu Glu Thr 
    1160                 1165                 1170             


Val Lys  Glu Met Ile Thr Leu  Leu Val Ala Lys Phe  Val Thr Ile 
    1175                 1180                 1185             


Leu Glu  Gly Val Leu Ala Lys  Leu Ser Arg Tyr Asp  Glu Gly Thr 
    1190                 1195                 1200             


Leu Phe  Ser Ser Phe Leu Ser  Phe Thr Val Lys Ala  Ala Ser Lys 
    1205                 1210                 1215             


Tyr Val  Asp Val Pro Lys Pro  Gly Met Asp Val Ala  Asp Ala Tyr 
    1220                 1225                 1230             


Val Thr  Phe Val Arg His Ser  Gln Asp Val Leu Arg  Asp Lys Val 
    1235                 1240                 1245             


Asn Glu  Glu Met Tyr Ile Glu  Arg Leu Phe Asp Gln  Trp Tyr Asn 
    1250                 1255                 1260             


Ser Ser  Met Asn Val Ile Cys  Thr Trp Leu Thr Asp  Arg Met Asp 
    1265                 1270                 1275             


Leu Gln  Leu His Ile Tyr Gln  Leu Lys Thr Leu Ile  Arg Met Val 
    1280                 1285                 1290             


Lys Lys  Thr Tyr Arg Asp Phe  Arg Leu Gln Gly Val  Leu Asp Ser 
    1295                 1300                 1305             


Thr Leu  Asn Ser Lys Thr Tyr  Glu Thr Ile Arg Asn  Arg Leu Thr 
    1310                 1315                 1320             


Val Glu  Glu Ala Thr Ala Ser  Val Ser Glu Gly Gly  Gly Leu Gln 
    1325                 1330                 1335             


Gly Ile  Ser Met Lys Asp Ser  Asp Glu Glu Asp Glu  Glu Asp Asp 
    1340                 1345                 1350             


<210>  3450
<211>  108
<212>  PRT
<213>  homo sapiens

<400>  3450

Met Ser Leu Thr Ser Ser Ser Ser Val Arg Val Glu Trp Ile Ala Ala 
1               5                   10                  15      


Val Thr Ile Ala Ala Gly Thr Ala Ala Ile Gly Tyr Leu Ala Tyr Lys 
            20                  25                  30          


Arg Phe Tyr Val Lys Asp His Arg Asn Lys Ala Met Ile Asn Leu His 
        35                  40                  45              


Ile Gln Lys Asp Asn Pro Lys Ile Val His Ala Phe Asp Met Glu Asp 
    50                  55                  60                  


Leu Gly Asp Lys Ala Val Tyr Cys Arg Cys Trp Arg Ser Lys Lys Phe 
65                  70                  75                  80  


Pro Phe Cys Asp Gly Ala His Thr Lys His Asn Glu Glu Thr Gly Asp 
                85                  90                  95      


Asn Val Gly Pro Leu Ile Ile Lys Lys Lys Glu Thr 
            100                 105             


<210>  3451
<211>  2490
<212>  PRT
<213>  homo sapiens

<400>  3451

Met His Val Ser Leu Ala Glu Ala Leu Glu Val Arg Gly Gly Pro Leu 
1               5                   10                  15      


Gln Glu Glu Glu Ile Trp Ala Val Leu Asn Gln Ser Ala Glu Ser Leu 
            20                  25                  30          


Gln Glu Leu Phe Arg Lys Val Ser Leu Ala Asp Pro Ala Ala Leu Gly 
        35                  40                  45              


Phe Ile Ile Ser Pro Trp Ser Leu Leu Leu Leu Pro Ser Gly Ser Val 
    50                  55                  60                  


Ser Phe Thr Asp Glu Asn Ile Ser Asn Gln Asp Leu Arg Ala Phe Thr 
65                  70                  75                  80  


Ala Pro Glu Val Leu Gln Asn Gln Ser Leu Thr Ser Leu Ser Asp Val 
                85                  90                  95      


Glu Lys Ile His Ile Tyr Ser Leu Gly Met Thr Leu Tyr Trp Gly Ala 
            100                 105                 110         


Asp Tyr Glu Val Pro Gln Ser Gln Pro Ile Lys Leu Gly Asp His Leu 
        115                 120                 125             


Asn Ser Ile Leu Leu Gly Met Cys Glu Asp Val Ile Tyr Ala Arg Val 
    130                 135                 140                 


Ser Val Arg Thr Val Leu Asp Ala Cys Ser Ala His Ile Arg Asn Ser 
145                 150                 155                 160 


Asn Cys Ala Pro Ser Phe Ser Tyr Val Lys His Leu Val Lys Leu Val 
                165                 170                 175     


Leu Gly Asn Leu Ser Gly Thr Asp Gln Leu Ser Cys Asn Ser Glu Gln 
            180                 185                 190         


Lys Pro Asp Arg Ser Gln Ala Ile Arg Asp Arg Leu Arg Gly Lys Gly 
        195                 200                 205             


Leu Pro Thr Gly Arg Ser Ser Thr Ser Asp Val Leu Asp Ile Gln Lys 
    210                 215                 220                 


Pro Pro Leu Ser His Gln Thr Phe Leu Asn Lys Gly Leu Ser Lys Ser 
225                 230                 235                 240 


Met Gly Phe Leu Ser Ile Lys Asp Thr Gln Asp Glu Asn Tyr Phe Lys 
                245                 250                 255     


Asp Ile Leu Ser Asp Asn Ser Gly Arg Glu Asp Ser Glu Asn Thr Phe 
            260                 265                 270         


Ser Pro Tyr Gln Phe Lys Thr Ser Gly Pro Glu Lys Lys Pro Ile Pro 
        275                 280                 285             


Gly Ile Asp Val Leu Ser Lys Lys Lys Ile Trp Ala Ser Ser Met Asp 
    290                 295                 300                 


Leu Leu Cys Thr Ala Asp Arg Asp Phe Ser Ser Gly Glu Thr Ala Thr 
305                 310                 315                 320 


Tyr Arg Arg Cys His Pro Glu Ala Val Thr Val Arg Thr Ser Thr Thr 
                325                 330                 335     


Pro Arg Lys Lys Glu Ala Arg Tyr Ser Asp Gly Ser Ile Ala Leu Asp 
            340                 345                 350         


Ile Phe Gly Pro Gln Lys Met Asp Pro Ile Tyr His Thr Arg Glu Leu 
        355                 360                 365             


Pro Thr Ser Ser Ala Ile Ser Ser Ala Leu Asp Arg Ile Arg Glu Arg 
    370                 375                 380                 


Gln Lys Lys Leu Gln Val Leu Arg Glu Ala Met Asn Val Glu Glu Pro 
385                 390                 395                 400 


Val Arg Arg Tyr Lys Thr Tyr His Gly Asp Val Phe Ser Thr Ser Ser 
                405                 410                 415     


Glu Ser Pro Ser Ile Ile Ser Ser Glu Ser Asp Phe Arg Gln Val Arg 
            420                 425                 430         


Arg Ser Glu Ala Ser Lys Arg Phe Glu Ser Ser Ser Gly Leu Pro Gly 
        435                 440                 445             


Val Asp Glu Thr Leu Ser Gln Gly Gln Ser Gln Arg Pro Ser Arg Gln 
    450                 455                 460                 


Tyr Glu Thr Pro Phe Glu Gly Asn Leu Ile Asn Gln Glu Ile Met Leu 
465                 470                 475                 480 


Lys Arg Gln Glu Glu Glu Leu Met Gln Leu Gln Ala Lys Met Ala Leu 
                485                 490                 495     


Arg Gln Ser Arg Leu Ser Leu Tyr Pro Gly Asp Thr Ile Lys Ala Ser 
            500                 505                 510         


Met Leu Asp Ile Thr Arg Asp Pro Leu Arg Glu Ile Ala Leu Glu Thr 
        515                 520                 525             


Ala Met Thr Gln Arg Lys Leu Arg Asn Phe Phe Gly Pro Glu Phe Val 
    530                 535                 540                 


Lys Met Thr Ile Glu Pro Phe Ile Ser Leu Asp Leu Pro Arg Ser Ile 
545                 550                 555                 560 


Leu Thr Lys Lys Gly Lys Asn Glu Asp Asn Arg Arg Lys Val Asn Ile 
                565                 570                 575     


Met Leu Leu Asn Gly Gln Arg Leu Glu Leu Thr Cys Asp Thr Lys Thr 
            580                 585                 590         


Ile Cys Lys Asp Val Phe Asp Met Val Val Ala His Ile Gly Leu Val 
        595                 600                 605             


Glu His His Leu Phe Ala Leu Ala Thr Leu Lys Asp Asn Glu Tyr Phe 
    610                 615                 620                 


Phe Val Asp Pro Asp Leu Lys Leu Thr Lys Val Ala Pro Glu Gly Trp 
625                 630                 635                 640 


Lys Glu Glu Pro Lys Lys Lys Thr Lys Ala Thr Val Asn Phe Thr Leu 
                645                 650                 655     


Phe Phe Arg Ile Lys Phe Phe Met Asp Asp Val Ser Leu Ile Gln His 
            660                 665                 670         


Thr Leu Thr Cys His Gln Tyr Tyr Leu Gln Leu Arg Lys Asp Ile Leu 
        675                 680                 685             


Glu Glu Arg Met His Cys Asp Asp Glu Thr Ser Leu Leu Leu Ala Ser 
    690                 695                 700                 


Leu Ala Leu Gln Ala Glu Tyr Gly Asp Tyr Gln Pro Glu Val His Gly 
705                 710                 715                 720 


Val Ser Tyr Phe Arg Met Glu His Tyr Leu Pro Ala Arg Val Met Glu 
                725                 730                 735     


Lys Leu Asp Leu Ser Tyr Ile Lys Glu Glu Leu Pro Lys Leu His Asn 
            740                 745                 750         


Thr Tyr Val Gly Ala Ser Glu Lys Glu Thr Glu Leu Glu Phe Leu Lys 
        755                 760                 765             


Val Cys Gln Arg Leu Thr Glu Tyr Gly Val His Phe His Arg Val His 
    770                 775                 780                 


Pro Glu Lys Lys Ser Gln Thr Gly Ile Leu Leu Gly Val Cys Ser Lys 
785                 790                 795                 800 


Gly Val Leu Val Phe Glu Val His Asn Gly Val Arg Thr Leu Val Leu 
                805                 810                 815     


Arg Phe Pro Trp Arg Glu Thr Lys Lys Ile Ser Phe Ser Lys Lys Lys 
            820                 825                 830         


Ile Thr Leu Gln Asn Thr Ser Asp Gly Ile Lys His Gly Phe Gln Thr 
        835                 840                 845             


Asp Asn Ser Lys Ile Cys Gln Tyr Leu Leu His Leu Cys Ser Tyr Gln 
    850                 855                 860                 


His Lys Phe Gln Leu Gln Met Arg Ala Arg Gln Ser Asn Gln Asp Ala 
865                 870                 875                 880 


Gln Asp Ile Glu Arg Ala Ser Phe Arg Ser Leu Asn Leu Gln Ala Glu 
                885                 890                 895     


Ser Val Arg Gly Phe Asn Met Gly Arg Ala Ile Ser Thr Gly Ser Leu 
            900                 905                 910         


Ala Ser Ser Thr Leu Asn Lys Leu Ala Val Arg Pro Leu Ser Val Gln 
        915                 920                 925             


Ala Glu Ile Leu Lys Arg Leu Ser Cys Ser Glu Leu Ser Leu Tyr Gln 
    930                 935                 940                 


Pro Leu Gln Asn Ser Ser Lys Glu Lys Asn Asp Lys Ala Ser Trp Glu 
945                 950                 955                 960 


Glu Lys Pro Arg Glu Met Ser Lys Ser Tyr His Asp Leu Ser Gln Ala 
                965                 970                 975     


Ser Leu Tyr Pro His Arg Lys Asn Val Ile Val Asn Met Glu Pro Pro 
            980                 985                 990         


Pro Gln Thr Val Ala Glu Leu Val  Gly Lys Pro Ser His  Gln Met Ser 
        995                 1000                 1005             


Arg Ser  Asp Ala Glu Ser Leu  Ala Gly Val Thr Lys  Leu Asn Asn 
    1010                 1015                 1020             


Ser Lys  Ser Val Ala Ser Leu  Asn Arg Ser Pro Glu  Arg Arg Lys 
    1025                 1030                 1035             


His Glu  Ser Asp Ser Ser Ser  Ile Glu Asp Pro Gly  Gln Ala Tyr 
    1040                 1045                 1050             


Val Leu  Gly Met Thr Met His  Ser Ser Gly Asn Ser  Ser Ser Gln 
    1055                 1060                 1065             


Val Pro  Leu Lys Glu Asn Asp  Val Leu His Lys Arg  Trp Ser Ile 
    1070                 1075                 1080             


Val Ser  Ser Pro Glu Arg Glu  Ile Thr Leu Val Asn  Leu Lys Lys 
    1085                 1090                 1095             


Asp Ala  Lys Tyr Gly Leu Gly  Phe Gln Ile Ile Gly  Gly Glu Lys 
    1100                 1105                 1110             


Met Gly  Arg Leu Asp Leu Gly  Ile Phe Ile Ser Ser  Val Ala Pro 
    1115                 1120                 1125             


Gly Gly  Pro Ala Asp Leu Asp  Gly Cys Leu Lys Pro  Gly Asp Arg 
    1130                 1135                 1140             


Leu Ile  Ser Val Asn Ser Val  Ser Leu Glu Gly Val  Ser His His 
    1145                 1150                 1155             


Ala Ala  Ile Glu Ile Leu Gln  Asn Ala Pro Glu Asp  Val Thr Leu 
    1160                 1165                 1170             


Val Ile  Ser Gln Pro Lys Glu  Lys Ile Ser Lys Val  Pro Ser Thr 
    1175                 1180                 1185             


Pro Val  His Leu Thr Asn Glu  Met Lys Asn Tyr Met  Lys Lys Ser 
    1190                 1195                 1200             


Ser Tyr  Met Gln Asp Ser Ala  Ile Asp Ser Ser Ser  Lys Asp His 
    1205                 1210                 1215             


His Trp  Ser Arg Gly Thr Leu  Arg His Ile Ser Glu  Asn Ser Phe 
    1220                 1225                 1230             


Gly Pro  Ser Gly Gly Leu Arg  Glu Gly Ser Leu Ser  Ser Gln Asp 
    1235                 1240                 1245             


Ser Arg  Thr Glu Ser Ala Ser  Leu Ser Gln Ser Gln  Val Asn Gly 
    1250                 1255                 1260             


Phe Phe  Ala Ser His Leu Gly  Asp Gln Thr Trp Gln  Glu Ser Gln 
    1265                 1270                 1275             


His Gly  Ser Pro Ser Pro Ser  Val Ile Ser Lys Ala  Thr Glu Lys 
    1280                 1285                 1290             


Glu Thr  Phe Thr Asp Ser Asn  Gln Ser Lys Thr Lys  Lys Pro Gly 
    1295                 1300                 1305             


Ile Ser  Asp Val Thr Asp Tyr  Ser Asp Arg Gly Asp  Ser Asp Met 
    1310                 1315                 1320             


Asp Glu  Ala Thr Tyr Ser Ser  Ser Gln Asp His Gln  Thr Pro Lys 
    1325                 1330                 1335             


Gln Glu  Ser Ser Ser Ser Val  Asn Thr Ser Asn Lys  Met Asn Phe 
    1340                 1345                 1350             


Lys Thr  Phe Ser Ser Ser Pro  Pro Lys Pro Gly Asp  Ile Phe Glu 
    1355                 1360                 1365             


Val Glu  Leu Ala Lys Asn Asp  Asn Ser Leu Gly Ile  Ser Val Thr 
    1370                 1375                 1380             


Val Leu  Phe Asp Lys Gly Gly  Val Asn Thr Ser Val  Arg His Gly 
    1385                 1390                 1395             


Gly Ile  Tyr Val Lys Ala Val  Ile Pro Gln Gly Ala  Ala Glu Ser 
    1400                 1405                 1410             


Asp Gly  Arg Ile His Lys Gly  Asp Arg Val Leu Ala  Val Asn Gly 
    1415                 1420                 1425             


Val Ser  Leu Glu Gly Ala Thr  His Lys Gln Ala Val  Glu Thr Leu 
    1430                 1435                 1440             


Arg Asn  Thr Gly Gln Val Val  His Leu Leu Leu Glu  Lys Gly Gln 
    1445                 1450                 1455             


Ser Pro  Thr Ser Lys Glu His  Val Pro Val Thr Pro  Gln Cys Thr 
    1460                 1465                 1470             


Leu Ser  Asp Gln Asn Ala Gln  Gly Gln Gly Pro Glu  Lys Val Lys 
    1475                 1480                 1485             


Lys Thr  Thr Gln Val Lys Asp  Tyr Ser Phe Val Thr  Glu Glu Asn 
    1490                 1495                 1500             


Thr Phe  Glu Val Lys Leu Phe  Lys Asn Ser Ser Gly  Leu Gly Phe 
    1505                 1510                 1515             


Ser Phe  Ser Arg Glu Asp Asn  Leu Ile Pro Glu Gln  Ile Asn Ala 
    1520                 1525                 1530             


Ser Ile  Val Arg Val Lys Lys  Leu Phe Pro Gly Gln  Pro Ala Ala 
    1535                 1540                 1545             


Glu Ser  Gly Lys Ile Asp Val  Gly Asp Val Ile Leu  Lys Val Asn 
    1550                 1555                 1560             


Gly Ala  Ser Leu Lys Gly Leu  Ser Gln Gln Glu Val  Ile Ser Ala 
    1565                 1570                 1575             


Leu Arg  Gly Thr Ala Pro Glu  Val Phe Leu Leu Leu  Cys Arg Pro 
    1580                 1585                 1590             


Pro Pro  Gly Val Leu Pro Glu  Ile Asp Thr Ala Leu  Leu Thr Pro 
    1595                 1600                 1605             


Leu Gln  Ser Pro Ala Gln Val  Leu Pro Asn Ser Ser  Lys Asp Ser 
    1610                 1615                 1620             


Ser Gln  Pro Ser Cys Val Glu  Gln Ser Thr Ser Ser  Asp Glu Asn 
    1625                 1630                 1635             


Glu Met  Ser Asp Lys Ser Lys  Lys Gln Cys Lys Ser  Pro Ser Arg 
    1640                 1645                 1650             


Arg Asp  Ser Tyr Ser Asp Ser  Ser Gly Ser Gly Glu  Asp Asp Leu 
    1655                 1660                 1665             


Val Thr  Ala Pro Ala Asn Ile  Ser Asn Ser Thr Trp  Ser Ser Ala 
    1670                 1675                 1680             


Leu His  Gln Thr Leu Ser Asn  Met Val Ser Gln Ala  Gln Ser His 
    1685                 1690                 1695             


His Glu  Ala Pro Lys Ser Gln  Glu Asp Thr Ile Cys  Thr Met Phe 
    1700                 1705                 1710             


Tyr Tyr  Pro Gln Lys Ile Pro  Asn Lys Pro Glu Phe  Glu Asp Ser 
    1715                 1720                 1725             


Asn Pro  Ser Pro Leu Pro Pro  Asp Met Ala Pro Gly  Gln Ser Tyr 
    1730                 1735                 1740             


Gln Pro  Gln Ser Glu Ser Ala  Ser Ser Ser Ser Met  Asp Lys Tyr 
    1745                 1750                 1755             


His Ile  His His Ile Ser Glu  Pro Thr Arg Gln Glu  Asn Trp Thr 
    1760                 1765                 1770             


Pro Leu  Lys Asn Asp Leu Glu  Asn His Leu Glu Asp  Phe Glu Leu 
    1775                 1780                 1785             


Glu Val  Glu Leu Leu Ile Thr  Leu Ile Lys Ser Glu  Lys Gly Ser 
    1790                 1795                 1800             


Leu Gly  Phe Thr Val Thr Lys  Gly Asn Gln Arg Ile  Gly Cys Tyr 
    1805                 1810                 1815             


Val His  Asp Val Ile Gln Asp  Pro Ala Lys Ser Asp  Gly Arg Leu 
    1820                 1825                 1830             


Lys Pro  Gly Asp Arg Leu Ile  Lys Val Asn Asp Thr  Asp Val Thr 
    1835                 1840                 1845             


Asn Met  Thr His Thr Asp Ala  Val Asn Leu Leu Arg  Ala Ala Ser 
    1850                 1855                 1860             


Lys Thr  Val Arg Leu Val Ile  Gly Arg Val Leu Glu  Leu Pro Arg 
    1865                 1870                 1875             


Ile Pro  Met Leu Pro His Leu  Leu Pro Asp Ile Thr  Leu Thr Cys 
    1880                 1885                 1890             


Asn Lys  Glu Glu Leu Gly Phe  Ser Leu Cys Gly Gly  His Asp Ser 
    1895                 1900                 1905             


Leu Tyr  Gln Val Val Tyr Ile  Ser Asp Ile Asn Pro  Arg Ser Val 
    1910                 1915                 1920             


Ala Ala  Ile Glu Gly Asn Leu  Gln Leu Leu Asp Val  Ile His Tyr 
    1925                 1930                 1935             


Val Asn  Gly Val Ser Thr Gln  Gly Met Thr Leu Glu  Glu Val Asn 
    1940                 1945                 1950             


Arg Ala  Leu Asp Met Ser Leu  Pro Ser Leu Val Leu  Lys Ala Thr 
    1955                 1960                 1965             


Arg Asn  Asp Leu Pro Val Val  Pro Ser Ser Lys Arg  Ser Ala Val 
    1970                 1975                 1980             


Ser Ala  Pro Lys Ser Thr Lys  Gly Asn Gly Ser Tyr  Ser Val Gly 
    1985                 1990                 1995             


Ser Cys  Ser Gln Pro Ala Leu  Thr Pro Asn Asp Ser  Phe Ser Thr 
    2000                 2005                 2010             


Val Ala  Gly Glu Glu Ile Asn  Glu Ile Ser Tyr Pro  Lys Gly Lys 
    2015                 2020                 2025             


Cys Ser  Thr Tyr Gln Ile Lys  Gly Ser Pro Asn Leu  Thr Leu Pro 
    2030                 2035                 2040             


Lys Glu  Ser Tyr Ile Gln Glu  Asp Asp Ile Tyr Asp  Asp Ser Gln 
    2045                 2050                 2055             


Glu Ala  Glu Val Ile Gln Ser  Leu Leu Asp Val Val  Asp Glu Glu 
    2060                 2065                 2070             


Ala Gln  Asn Leu Leu Asn Glu  Asn Asn Ala Ala Gly  Tyr Ser Cys 
    2075                 2080                 2085             


Gly Pro  Gly Thr Leu Lys Met  Asn Gly Lys Leu Ser  Glu Glu Arg 
    2090                 2095                 2100             


Thr Glu  Asp Thr Asp Cys Asp  Gly Ser Pro Leu Pro  Glu Tyr Phe 
    2105                 2110                 2115             


Thr Glu  Ala Thr Lys Met Asn  Gly Cys Glu Glu Tyr  Cys Glu Glu 
    2120                 2125                 2130             


Lys Val  Lys Ser Glu Ser Leu  Ile Gln Lys Pro Gln  Glu Lys Lys 
    2135                 2140                 2145             


Thr Asp  Asp Asp Glu Ile Thr  Trp Gly Asn Asp Glu  Leu Pro Ile 
    2150                 2155                 2160             


Glu Arg  Thr Asn His Glu Asp  Ser Asp Lys Asp His  Ser Phe Leu 
    2165                 2170                 2175             


Thr Asn  Asp Glu Leu Ala Val  Leu Pro Val Val Lys  Val Leu Pro 
    2180                 2185                 2190             


Ser Gly  Lys Tyr Thr Gly Ala  Asn Leu Lys Ser Val  Ile Arg Val 
    2195                 2200                 2205             


Leu Arg  Gly Leu Leu Asp Gln  Gly Ile Pro Ser Lys  Glu Leu Glu 
    2210                 2215                 2220             


Asn Leu  Gln Glu Leu Lys Pro  Leu Asp Gln Cys Leu  Ile Gly Gln 
    2225                 2230                 2235             


Thr Lys  Glu Asn Arg Arg Lys  Asn Arg Tyr Lys Asn  Ile Leu Pro 
    2240                 2245                 2250             


Tyr Asp  Ala Thr Arg Val Pro  Leu Gly Asp Glu Gly  Gly Tyr Ile 
    2255                 2260                 2265             


Asn Ala  Ser Phe Ile Lys Ile  Pro Val Gly Lys Glu  Glu Phe Val 
    2270                 2275                 2280             


Tyr Ile  Ala Cys Gln Gly Pro  Leu Pro Thr Thr Val  Gly Asp Phe 
    2285                 2290                 2295             


Trp Gln  Met Ile Trp Glu Gln  Lys Ser Thr Val Ile  Ala Met Met 
    2300                 2305                 2310             


Thr Gln  Glu Val Glu Gly Glu  Lys Ile Lys Cys Gln  Arg Tyr Trp 
    2315                 2320                 2325             


Pro Asn  Ile Leu Gly Lys Thr  Thr Met Val Ser Asn  Arg Leu Arg 
    2330                 2335                 2340             


Leu Ala  Leu Val Arg Met Gln  Gln Leu Lys Gly Phe  Val Val Arg 
    2345                 2350                 2355             


Ala Met  Thr Leu Glu Asp Ile  Gln Thr Arg Glu Val  Arg His Ile 
    2360                 2365                 2370             


Ser His  Leu Asn Phe Thr Ala  Trp Pro Asp His Asp  Thr Pro Ser 
    2375                 2380                 2385             


Gln Pro  Asp Asp Leu Leu Thr  Phe Ile Ser Tyr Met  Arg His Ile 
    2390                 2395                 2400             


His Arg  Ser Gly Pro Ile Ile  Thr His Cys Ser Ala  Gly Ile Gly 
    2405                 2410                 2415             


Arg Ser  Gly Thr Leu Ile Cys  Ile Asp Val Val Leu  Gly Leu Ile 
    2420                 2425                 2430             


Ser Gln  Asp Leu Asp Phe Asp  Ile Ser Asp Leu Val  Arg Cys Met 
    2435                 2440                 2445             


Arg Leu  Gln Arg His Gly Met  Val Gln Thr Glu Asp  Gln Tyr Ile 
    2450                 2455                 2460             


Phe Cys  Tyr Gln Val Ile Leu  Tyr Val Leu Thr Arg  Leu Gln Ala 
    2465                 2470                 2475             


Glu Glu  Glu Gln Lys Gln Gln  Pro Gln Leu Leu Lys  
    2480                 2485                 2490 


<210>  3452
<211>  450
<212>  PRT
<213>  homo sapiens

<400>  3452

Met Gln Pro Pro Arg Glu Arg Leu Val Val Thr Gly Arg Ala Gly Trp 
1               5                   10                  15      


Met Gly Met Gly Arg Gly Ala Gly Arg Ser Ala Leu Gly Phe Trp Pro 
            20                  25                  30          


Thr Leu Ala Phe Leu Leu Cys Ser Phe Pro Ala Ala Thr Ser Pro Cys 
        35                  40                  45              


Lys Ile Leu Lys Cys Asn Ser Glu Phe Trp Ser Ala Thr Ser Gly Ser 
    50                  55                  60                  


His Ala Pro Ala Ser Asp Asp Thr Pro Glu Phe Cys Ala Ala Leu Arg 
65                  70                  75                  80  


Ser Tyr Ala Leu Cys Thr Arg Arg Thr Ala Arg Thr Cys Arg Gly Asp 
                85                  90                  95      


Leu Ala Tyr His Ser Ala Val His Gly Ile Glu Asp Leu Met Ser Gln 
            100                 105                 110         


His Asn Cys Ser Lys Asp Gly Pro Thr Ser Gln Pro Arg Leu Arg Thr 
        115                 120                 125             


Leu Pro Pro Ala Gly Asp Ser Gln Glu Arg Ser Asp Ser Pro Glu Ile 
    130                 135                 140                 


Cys His Tyr Glu Lys Ser Phe His Lys His Ser Ala Thr Pro Asn Tyr 
145                 150                 155                 160 


Thr His Cys Gly Leu Phe Gly Asp Pro His Leu Arg Thr Phe Thr Asp 
                165                 170                 175     


Arg Phe Gln Thr Cys Lys Val Gln Gly Ala Trp Pro Leu Ile Asp Asn 
            180                 185                 190         


Asn Tyr Leu Asn Val Gln Val Thr Asn Thr Pro Val Leu Pro Gly Ser 
        195                 200                 205             


Ala Ala Thr Ala Thr Ser Lys Leu Thr Ile Ile Phe Lys Asn Phe Gln 
    210                 215                 220                 


Glu Cys Val Asp Gln Lys Val Tyr Gln Ala Glu Met Asp Glu Leu Pro 
225                 230                 235                 240 


Ala Ala Phe Val Asp Gly Ser Lys Asn Gly Gly Asp Lys His Gly Ala 
                245                 250                 255     


Asn Ser Leu Lys Ile Thr Glu Lys Val Ser Gly Gln His Val Glu Ile 
            260                 265                 270         


Gln Ala Lys Tyr Ile Gly Thr Thr Ile Val Val Arg Gln Val Gly Arg 
        275                 280                 285             


Tyr Leu Thr Phe Ala Val Arg Met Pro Glu Glu Val Val Asn Ala Val 
    290                 295                 300                 


Glu Asp Trp Asp Ser Gln Gly Leu Tyr Leu Cys Leu Arg Gly Cys Pro 
305                 310                 315                 320 


Leu Asn Gln Gln Ile Asp Phe Gln Ala Phe His Thr Asn Ala Glu Gly 
                325                 330                 335     


Thr Gly Ala Arg Arg Leu Ala Ala Ala Ser Pro Ala Pro Thr Ala Pro 
            340                 345                 350         


Glu Thr Phe Pro Tyr Glu Thr Ala Val Ala Lys Cys Lys Glu Lys Leu 
        355                 360                 365             


Pro Val Glu Asp Leu Tyr Tyr Gln Ala Cys Val Phe Asp Leu Leu Thr 
    370                 375                 380                 


Thr Gly Asp Val Asn Phe Thr Leu Ala Ala Tyr Tyr Ala Leu Glu Asp 
385                 390                 395                 400 


Val Lys Met Leu His Ser Asn Lys Asp Lys Leu His Leu Tyr Glu Arg 
                405                 410                 415     


Thr Arg Asp Leu Pro Gly Arg Ala Ala Ala Gly Leu Pro Leu Ala Pro 
            420                 425                 430         


Arg Pro Leu Leu Gly Ala Leu Val Pro Leu Leu Ala Leu Leu Pro Val 
        435                 440                 445             


Phe Cys 
    450 


<210>  3453
<211>  434
<212>  PRT
<213>  homo sapiens

<400>  3453

Met Gly Met Gly Arg Gly Ala Gly Arg Ser Ala Leu Gly Phe Trp Pro 
1               5                   10                  15      


Thr Leu Ala Phe Leu Leu Cys Ser Phe Pro Ala Ala Thr Ser Pro Cys 
            20                  25                  30          


Lys Ile Leu Lys Cys Asn Ser Glu Phe Trp Ser Ala Thr Ser Gly Ser 
        35                  40                  45              


His Ala Pro Ala Ser Asp Asp Thr Pro Glu Phe Cys Ala Ala Leu Arg 
    50                  55                  60                  


Ser Tyr Ala Leu Cys Thr Arg Arg Thr Ala Arg Thr Cys Arg Gly Asp 
65                  70                  75                  80  


Leu Ala Tyr His Ser Ala Val His Gly Ile Glu Asp Leu Met Ser Gln 
                85                  90                  95      


His Asn Cys Ser Lys Asp Gly Pro Thr Ser Gln Pro Arg Leu Arg Thr 
            100                 105                 110         


Leu Pro Pro Ala Gly Asp Ser Gln Glu Arg Ser Asp Ser Pro Glu Ile 
        115                 120                 125             


Cys His Tyr Glu Lys Ser Phe His Lys His Ser Ala Thr Pro Asn Tyr 
    130                 135                 140                 


Thr His Cys Gly Leu Phe Gly Asp Pro His Leu Arg Thr Phe Thr Asp 
145                 150                 155                 160 


Arg Phe Gln Thr Cys Lys Val Gln Gly Ala Trp Pro Leu Ile Asp Asn 
                165                 170                 175     


Asn Tyr Leu Asn Val Gln Val Thr Asn Thr Pro Val Leu Pro Gly Ser 
            180                 185                 190         


Ala Ala Thr Ala Thr Ser Lys Leu Thr Ile Ile Phe Lys Asn Phe Gln 
        195                 200                 205             


Glu Cys Val Asp Gln Lys Val Tyr Gln Ala Glu Met Asp Glu Leu Pro 
    210                 215                 220                 


Ala Ala Phe Val Asp Gly Ser Lys Asn Gly Gly Asp Lys His Gly Ala 
225                 230                 235                 240 


Asn Ser Leu Lys Ile Thr Glu Lys Val Ser Gly Gln His Val Glu Ile 
                245                 250                 255     


Gln Ala Lys Tyr Ile Gly Thr Thr Ile Val Val Arg Gln Val Gly Arg 
            260                 265                 270         


Tyr Leu Thr Phe Ala Val Arg Met Pro Glu Glu Val Val Asn Ala Val 
        275                 280                 285             


Glu Asp Trp Asp Ser Gln Gly Leu Tyr Leu Cys Leu Arg Gly Cys Pro 
    290                 295                 300                 


Leu Asn Gln Gln Ile Asp Phe Gln Ala Phe His Thr Asn Ala Glu Gly 
305                 310                 315                 320 


Thr Gly Ala Arg Arg Leu Ala Ala Ala Ser Pro Ala Pro Thr Ala Pro 
                325                 330                 335     


Glu Thr Phe Pro Tyr Glu Thr Ala Val Ala Lys Cys Lys Glu Lys Leu 
            340                 345                 350         


Pro Val Glu Asp Leu Tyr Tyr Gln Ala Cys Val Phe Asp Leu Leu Thr 
        355                 360                 365             


Thr Gly Asp Val Asn Phe Thr Leu Ala Ala Tyr Tyr Ala Leu Glu Asp 
    370                 375                 380                 


Val Lys Met Leu His Ser Asn Lys Asp Lys Leu His Leu Tyr Glu Arg 
385                 390                 395                 400 


Thr Arg Asp Leu Pro Gly Arg Ala Ala Ala Gly Leu Pro Leu Ala Pro 
                405                 410                 415     


Arg Pro Leu Leu Gly Ala Leu Val Pro Leu Leu Ala Leu Leu Pro Val 
            420                 425                 430         


Phe Cys 
        


<210>  3454
<211>  434
<212>  PRT
<213>  homo sapiens

<400>  3454

Met Gly Met Gly Arg Gly Ala Gly Arg Ser Ala Leu Gly Phe Trp Pro 
1               5                   10                  15      


Thr Leu Ala Phe Leu Leu Cys Ser Phe Pro Ala Ala Thr Ser Pro Cys 
            20                  25                  30          


Lys Ile Leu Lys Cys Asn Ser Glu Phe Trp Ser Ala Thr Ser Gly Ser 
        35                  40                  45              


His Ala Pro Ala Ser Asp Asp Thr Pro Glu Phe Cys Ala Ala Leu Arg 
    50                  55                  60                  


Ser Tyr Ala Leu Cys Thr Arg Arg Thr Ala Arg Thr Cys Arg Gly Asp 
65                  70                  75                  80  


Leu Ala Tyr His Ser Ala Val His Gly Ile Glu Asp Leu Met Ser Gln 
                85                  90                  95      


His Asn Cys Ser Lys Asp Gly Pro Thr Ser Gln Pro Arg Leu Arg Thr 
            100                 105                 110         


Leu Pro Pro Ala Gly Asp Ser Gln Glu Arg Ser Asp Ser Pro Glu Ile 
        115                 120                 125             


Cys His Tyr Glu Lys Ser Phe His Lys His Ser Ala Thr Pro Asn Tyr 
    130                 135                 140                 


Thr His Cys Gly Leu Phe Gly Asp Pro His Leu Arg Thr Phe Thr Asp 
145                 150                 155                 160 


Arg Phe Gln Thr Cys Lys Val Gln Gly Ala Trp Pro Leu Ile Asp Asn 
                165                 170                 175     


Asn Tyr Leu Asn Val Gln Val Thr Asn Thr Pro Val Leu Pro Gly Ser 
            180                 185                 190         


Ala Ala Thr Ala Thr Ser Lys Leu Thr Ile Ile Phe Lys Asn Phe Gln 
        195                 200                 205             


Glu Cys Val Asp Gln Lys Val Tyr Gln Ala Glu Met Asp Glu Leu Pro 
    210                 215                 220                 


Ala Ala Phe Val Asp Gly Ser Lys Asn Gly Gly Asp Lys His Gly Ala 
225                 230                 235                 240 


Asn Ser Leu Lys Ile Thr Glu Lys Val Ser Gly Gln His Val Glu Ile 
                245                 250                 255     


Gln Ala Lys Tyr Ile Gly Thr Thr Ile Val Val Arg Gln Val Gly Arg 
            260                 265                 270         


Tyr Leu Thr Phe Ala Val Arg Met Pro Glu Glu Val Val Asn Ala Val 
        275                 280                 285             


Glu Asp Trp Asp Ser Gln Gly Leu Tyr Leu Cys Leu Arg Gly Cys Pro 
    290                 295                 300                 


Leu Asn Gln Gln Ile Asp Phe Gln Ala Phe His Thr Asn Ala Glu Gly 
305                 310                 315                 320 


Thr Gly Ala Arg Arg Leu Ala Ala Ala Ser Pro Ala Pro Thr Ala Pro 
                325                 330                 335     


Glu Thr Phe Pro Tyr Glu Thr Ala Val Ala Lys Cys Lys Glu Lys Leu 
            340                 345                 350         


Pro Val Glu Asp Leu Tyr Tyr Gln Ala Cys Val Phe Asp Leu Leu Thr 
        355                 360                 365             


Thr Gly Asp Val Asn Phe Thr Leu Ala Ala Tyr Tyr Ala Leu Glu Asp 
    370                 375                 380                 


Val Lys Met Leu His Ser Asn Lys Asp Lys Leu His Leu Tyr Glu Arg 
385                 390                 395                 400 


Thr Arg Asp Leu Pro Gly Arg Ala Ala Ala Gly Leu Pro Leu Ala Pro 
                405                 410                 415     


Arg Pro Leu Leu Gly Ala Leu Val Pro Leu Leu Ala Leu Leu Pro Val 
            420                 425                 430         


Phe Cys 
        


<210>  3455
<211>  1264
<212>  PRT
<213>  homo sapiens

<400>  3455

Met His Pro Asp Leu Gly Pro Leu Cys Thr Leu Leu Tyr Val Thr Leu 
1               5                   10                  15      


Thr Ile Leu Cys Ser Ser Val Ser Ser Asp Leu Ala Pro Tyr Phe Thr 
            20                  25                  30          


Ser Glu Pro Leu Ser Ala Val Gln Lys Leu Gly Gly Pro Val Val Leu 
        35                  40                  45              


His Cys Ser Ala Gln Pro Val Thr Thr Arg Ile Ser Trp Leu His Asn 
    50                  55                  60                  


Gly Lys Thr Leu Asp Gly Asn Leu Glu His Val Lys Ile His Gln Gly 
65                  70                  75                  80  


Thr Leu Thr Ile Leu Ser Leu Asn Ser Ser Leu Leu Gly Tyr Tyr Gln 
                85                  90                  95      


Cys Leu Ala Asn Asn Ser Ile Gly Ala Ile Val Ser Gly Pro Ala Thr 
            100                 105                 110         


Val Ser Val Ala Val Leu Gly Asp Phe Gly Ser Ser Thr Lys His Val 
        115                 120                 125             


Ile Thr Ala Glu Glu Lys Ser Ala Gly Phe Ile Gly Cys Arg Val Pro 
    130                 135                 140                 


Glu Ser Asn Pro Lys Ala Glu Val Arg Tyr Lys Ile Arg Gly Lys Trp 
145                 150                 155                 160 


Leu Glu His Ser Thr Glu Asn Tyr Leu Ile Leu Pro Ser Gly Asn Leu 
                165                 170                 175     


Gln Ile Leu Asn Val Ser Leu Glu Asp Lys Gly Ser Tyr Lys Cys Ala 
            180                 185                 190         


Ala Tyr Asn Pro Val Thr His Gln Leu Lys Val Glu Pro Ile Gly Arg 
        195                 200                 205             


Lys Leu Leu Val Ser Arg Pro Ser Ser Asp Asp Val His Ile Leu His 
    210                 215                 220                 


Pro Thr His Ser Gln Ala Leu Ala Val Leu Ser Arg Ser Pro Val Thr 
225                 230                 235                 240 


Leu Glu Cys Val Val Ser Gly Val Pro Ala Pro Gln Val Tyr Trp Leu 
                245                 250                 255     


Lys Asp Gly Gln Asp Ile Ala Pro Gly Ser Asn Trp Arg Arg Leu Tyr 
            260                 265                 270         


Ser His Leu Ala Thr Asp Ser Val Asp Pro Ala Asp Ser Gly Asn Tyr 
        275                 280                 285             


Ser Cys Met Ala Gly Asn Lys Ser Gly Asp Val Lys Tyr Val Thr Tyr 
    290                 295                 300                 


Met Val Asn Val Leu Glu His Ala Ser Ile Ser Lys Gly Leu Gln Asp 
305                 310                 315                 320 


Gln Ile Val Ser Leu Gly Ala Thr Val His Phe Thr Cys Asp Val His 
                325                 330                 335     


Gly Asn Pro Ala Pro Asn Cys Thr Trp Phe His Asn Ala Gln Pro Ile 
            340                 345                 350         


His Pro Ser Ala Arg His Leu Thr Ala Gly Asn Gly Leu Lys Ile Ser 
        355                 360                 365             


Gly Val Thr Val Glu Asp Val Gly Met Tyr Gln Cys Val Ala Asp Asn 
    370                 375                 380                 


Gly Ile Gly Phe Met His Ser Thr Gly Arg Leu Glu Ile Glu Asn Asp 
385                 390                 395                 400 


Gly Gly Phe Lys Pro Val Ile Ile Thr Ala Pro Val Ser Ala Lys Val 
                405                 410                 415     


Ala Asp Gly Asp Phe Val Thr Leu Ser Cys Asn Ala Ser Gly Leu Pro 
            420                 425                 430         


Val Pro Val Ile Arg Trp Tyr Asp Ser His Gly Leu Ile Thr Ser His 
        435                 440                 445             


Pro Ser Gln Val Leu Arg Ser Lys Ser Arg Lys Ser Gln Leu Ser Arg 
    450                 455                 460                 


Pro Glu Gly Leu Asn Leu Glu Pro Val Tyr Phe Val Leu Ser Gln Ala 
465                 470                 475                 480 


Gly Ala Ser Ser Leu His Ile Gln Ala Val Thr Gln Glu His Ala Gly 
                485                 490                 495     


Lys Tyr Ile Cys Glu Ala Ala Asn Glu His Gly Thr Thr Gln Ala Glu 
            500                 505                 510         


Ala Ser Leu Met Val Val Pro Phe Glu Thr Asn Thr Lys Ala Glu Thr 
        515                 520                 525             


Val Thr Leu Pro Asp Ala Ala Gln Asn Asp Asp Arg Ser Lys Arg Asp 
    530                 535                 540                 


Gly Ser Glu Thr Gly Leu Leu Ser Ser Phe Pro Val Lys Val His Pro 
545                 550                 555                 560 


Ser Ala Val Glu Ser Ala Pro Glu Lys Asn Ala Ser Gly Ile Ser Val 
                565                 570                 575     


Pro Asp Ala Pro Ile Ile Leu Ser Pro Pro Gln Thr His Thr Pro Asp 
            580                 585                 590         


Thr Tyr Asn Leu Val Trp Arg Ala Gly Lys Asp Gly Gly Leu Pro Ile 
        595                 600                 605             


Asn Ala Tyr Phe Val Lys Tyr Arg Lys Leu Asp Asp Gly Val Gly Met 
    610                 615                 620                 


Leu Gly Ser Trp His Thr Val Arg Val Pro Gly Ser Glu Asn Glu Leu 
625                 630                 635                 640 


His Leu Ala Glu Leu Glu Pro Ser Ser Leu Tyr Glu Val Leu Met Val 
                645                 650                 655     


Ala Arg Ser Ala Ala Gly Glu Gly Gln Pro Ala Met Leu Thr Phe Arg 
            660                 665                 670         


Thr Ser Lys Glu Lys Thr Ala Ser Ser Lys Asn Thr Gln Ala Ser Ser 
        675                 680                 685             


Pro Pro Val Gly Ile Pro Lys Tyr Pro Val Val Ser Glu Ala Ala Asn 
    690                 695                 700                 


Asn Asn Phe Gly Val Val Leu Thr Asp Ser Ser Arg His Ser Gly Val 
705                 710                 715                 720 


Pro Glu Ala Pro Asp Arg Pro Thr Ile Ser Thr Ala Ser Glu Thr Ser 
                725                 730                 735     


Val Tyr Val Thr Trp Ile Pro Arg Ala Asn Gly Gly Ser Pro Ile Thr 
            740                 745                 750         


Ala Phe Lys Val Glu Tyr Lys Arg Met Arg Thr Ser Asn Trp Leu Val 
        755                 760                 765             


Ala Ala Glu Asp Ile Pro Pro Ser Lys Leu Ser Val Glu Val Arg Ser 
    770                 775                 780                 


Leu Glu Pro Gly Ser Thr Tyr Lys Phe Arg Val Ile Ala Ile Asn His 
785                 790                 795                 800 


Tyr Gly Glu Ser Phe Arg Ser Ser Ala Ser Arg Pro Tyr Gln Val Val 
                805                 810                 815     


Gly Phe Pro Asn Arg Phe Ser Ser Arg Pro Ile Thr Gly Pro His Ile 
            820                 825                 830         


Ala Tyr Thr Glu Ala Val Ser Asp Thr Gln Ile Met Leu Lys Trp Thr 
        835                 840                 845             


Tyr Ile Pro Ser Ser Asn Asn Asn Thr Pro Ile Gln Gly Phe Tyr Ile 
    850                 855                 860                 


Tyr Tyr Arg Pro Thr Asp Ser Asp Asn Asp Ser Asp Tyr Lys Arg Asp 
865                 870                 875                 880 


Val Val Glu Gly Ser Lys Gln Trp His Met Ile Gly His Leu Gln Pro 
                885                 890                 895     


Glu Thr Ser Tyr Asp Ile Lys Met Gln Cys Phe Asn Glu Gly Gly Glu 
            900                 905                 910         


Ser Glu Phe Ser Asn Val Met Ile Cys Glu Thr Lys Val Lys Arg Val 
        915                 920                 925             


Pro Gly Ala Ser Glu Tyr Pro Val Lys Asp Leu Ser Thr Pro Pro Asn 
    930                 935                 940                 


Ser Leu Gly Ser Gly Gly Asn Val Gly Pro Ala Thr Ser Pro Ala Arg 
945                 950                 955                 960 


Ser Ser Asp Met Leu Tyr Leu Ile Val Gly Cys Val Leu Gly Val Met 
                965                 970                 975     


Val Leu Ile Leu Met Val Phe Ile Ala Met Cys Leu Trp Lys Asn Arg 
            980                 985                 990         


Gln Gln Asn Thr Ile Gln Lys Tyr  Asp Pro Pro Gly Tyr  Leu Tyr Gln 
        995                 1000                 1005             


Gly Ser  Asp Met Asn Gly Gln  Met Val Asp Tyr Thr  Thr Leu Ser 
    1010                 1015                 1020             


Gly Ala  Ser Gln Ile Asn Gly  Asn Val His Gly Gly  Phe Leu Thr 
    1025                 1030                 1035             


Asn Gly  Gly Leu Ser Ser Gly  Tyr Ser His Leu His  His Lys Val 
    1040                 1045                 1050             


Pro Asn  Ala Val Asn Gly Ile  Val Asn Gly Ser Leu  Asn Gly Gly 
    1055                 1060                 1065             


Leu Tyr  Ser Gly His Ser Asn  Ser Leu Thr Arg Thr  His Val Asp 
    1070                 1075                 1080             


Phe Glu  His Pro His His Leu  Val Asn Gly Gly Gly  Met Tyr Thr 
    1085                 1090                 1095             


Ala Val  Pro Gln Ile Asp Pro  Leu Glu Cys Val Asn  Cys Arg Asn 
    1100                 1105                 1110             


Cys Arg  Asn Asn Asn Arg Cys  Phe Thr Lys Thr Asn  Ser Thr Phe 
    1115                 1120                 1125             


Ser Ser  Ser Pro Pro Pro Val  Val Pro Val Val Ala  Pro Tyr Pro 
    1130                 1135                 1140             


Gln Asp  Gly Leu Glu Met Lys  Pro Leu Ser His Val  Lys Val Pro 
    1145                 1150                 1155             


Val Cys  Leu Thr Ser Ala Val  Pro Asp Cys Gly Gln  Leu Pro Glu 
    1160                 1165                 1170             


Glu Ser  Val Lys Asp Asn Val  Glu Pro Val Pro Thr  Gln Arg Thr 
    1175                 1180                 1185             


Cys Cys  Gln Asp Ile Val Asn  Asp Val Ser Ser Asp  Gly Ser Glu 
    1190                 1195                 1200             


Asp Pro  Ala Glu Phe Ser Arg  Gly Asp Ser Cys Ala  His Ser Glu 
    1205                 1210                 1215             


Thr Glu  Ile Asn Ile Val Ser  Trp Asn Ala Leu Ile  Leu Pro Pro 
    1220                 1225                 1230             


Val Pro  Glu Gly Cys Ala Glu  Lys Thr Met Trp Ser  Pro Pro Gly 
    1235                 1240                 1245             


Ile Pro  Leu Asp Ser Pro Thr  Glu Val Leu Gln Gln  Pro Arg Glu 
    1250                 1255                 1260             


Thr 
    


<210>  3456
<211>  186
<212>  PRT
<213>  homo sapiens

<400>  3456

Met Phe Gly Lys Pro Asp Lys Met Asp Val Arg Cys His Ser Asp Ala 
1               5                   10                  15      


Glu Ala Ala Arg Val Ser Lys Asn Ala His Lys Glu Ser Arg Glu Ser 
            20                  25                  30          


Lys Gly Ala Glu Gly Asn Leu Pro Ala Ala Phe Leu Lys Glu Pro Gln 
        35                  40                  45              


Gly Ala Phe Ser Ala Ser Gly Ala Ala Glu Asp Cys Asn Lys Ser Lys 
    50                  55                  60                  


Ser Asn Ser Ala Ala Asp Pro Asp Tyr Cys Arg Arg Ile Leu Val Arg 
65                  70                  75                  80  


Asp Ala Lys Gly Ser Ile Arg Glu Ile Ile Leu Pro Lys Gly Leu Asp 
                85                  90                  95      


Leu Asp Arg Pro Lys Arg Thr Arg Thr Ser Phe Thr Ala Glu Gln Leu 
            100                 105                 110         


Tyr Arg Leu Glu Met Glu Phe Gln Arg Cys Gln Tyr Val Val Gly Arg 
        115                 120                 125             


Glu Arg Thr Glu Leu Ala Arg Gln Leu Asn Leu Ser Glu Thr Gln Ala 
    130                 135                 140                 


Asn Ser Glu Glu Asn Asn Glu Arg Phe Lys Arg Gly Ile Lys Lys Gln 
145                 150                 155                 160 


Lys Lys Lys Arg Lys Lys Glu Pro Ala Asn Asp Glu Ser Arg Arg Gly 
                165                 170                 175     


Asp Ser Gly Gly Arg Gly Trp Gln Pro Leu 
            180                 185     


<210>  3457
<211>  334
<212>  PRT
<213>  homo sapiens

<400>  3457

Met Phe Gly Lys Pro Asp Lys Met Asp Val Arg Cys His Ser Asp Ala 
1               5                   10                  15      


Glu Ala Ala Arg Val Ser Lys Asn Ala His Lys Glu Ser Arg Glu Ser 
            20                  25                  30          


Lys Gly Ala Glu Gly Asn Leu Pro Ala Ala Phe Leu Lys Glu Pro Gln 
        35                  40                  45              


Gly Ala Phe Ser Ala Ser Gly Ala Ala Glu Asp Cys Asn Lys Ser Lys 
    50                  55                  60                  


Ser Asn Ser Ala Ala Asp Pro Asp Tyr Cys Arg Arg Ile Leu Val Arg 
65                  70                  75                  80  


Asp Ala Lys Gly Ser Ile Arg Glu Ile Ile Leu Pro Lys Gly Leu Asp 
                85                  90                  95      


Leu Asp Arg Pro Lys Arg Thr Arg Thr Ser Phe Thr Ala Glu Gln Leu 
            100                 105                 110         


Tyr Arg Leu Glu Met Glu Phe Gln Arg Cys Gln Tyr Val Val Gly Arg 
        115                 120                 125             


Glu Arg Thr Glu Leu Ala Arg Gln Leu Asn Leu Ser Glu Thr Gln Val 
    130                 135                 140                 


Lys Val Trp Phe Gln Asn Arg Arg Thr Lys Gln Lys Lys Asp Gln Gly 
145                 150                 155                 160 


Lys Asp Ser Glu Leu Arg Ser Val Val Ser Glu Thr Ala Ala Thr Cys 
                165                 170                 175     


Ser Val Leu Arg Leu Leu Glu Gln Gly Arg Leu Leu Ser Pro Pro Gly 
            180                 185                 190         


Leu Pro Ala Leu Leu Pro Pro Cys Ala Thr Gly Ala Leu Gly Ser Ala 
        195                 200                 205             


Leu Arg Gly Pro Ser Leu Pro Ala Leu Gly Ala Gly Ala Ala Ala Gly 
    210                 215                 220                 


Ser Ala Ala Ala Ala Ala Ala Ala Ala Pro Gly Pro Ala Gly Ala Ala 
225                 230                 235                 240 


Ser Pro His Pro Pro Ala Val Gly Gly Ala Pro Gly Pro Gly Pro Ala 
                245                 250                 255     


Gly Pro Gly Gly Leu His Ala Gly Ala Pro Ala Ala Gly His Ser Leu 
            260                 265                 270         


Phe Ser Leu Pro Val Pro Ser Leu Leu Gly Ser Val Ala Ser Arg Leu 
        275                 280                 285             


Ser Ser Ala Pro Leu Thr Met Ala Gly Ser Leu Ala Gly Asn Leu Gln 
    290                 295                 300                 


Glu Leu Ser Ala Arg Tyr Leu Ser Ser Ser Ala Phe Glu Pro Tyr Ser 
305                 310                 315                 320 


Arg Thr Asn Asn Lys Glu Gly Ala Glu Lys Lys Ala Leu Asp 
                325                 330                 


<210>  3458
<211>  197
<212>  PRT
<213>  homo sapiens

<400>  3458

Met Ala Ala Val Lys Asp Ser Cys Gly Lys Gly Glu Met Ala Thr Gly 
1               5                   10                  15      


Asn Gly Arg Arg Leu His Leu Gly Ile Pro Glu Ala Val Phe Val Glu 
            20                  25                  30          


Asp Val Asp Ser Phe Met Lys Gln Pro Gly Asn Glu Thr Ala Asp Thr 
        35                  40                  45              


Val Leu Lys Lys Leu Asp Glu Gln Tyr Gln Lys Tyr Lys Phe Met Glu 
    50                  55                  60                  


Leu Asn Leu Ala Gln Lys Lys Arg Arg Leu Lys Gly Gln Ile Pro Glu 
65                  70                  75                  80  


Ile Lys Gln Thr Leu Glu Ile Leu Lys Tyr Met Gln Lys Lys Lys Glu 
                85                  90                  95      


Ser Thr Asn Ser Met Glu Thr Arg Phe Leu Leu Ala Asp Asn Leu Tyr 
            100                 105                 110         


Cys Lys Ala Ser Val Pro Pro Thr Asp Lys Val Cys Leu Trp Leu Gly 
        115                 120                 125             


Ala Asn Val Met Leu Glu Tyr Asp Ile Asp Glu Ala Gln Ala Leu Leu 
    130                 135                 140                 


Glu Lys Asn Leu Ser Thr Ala Thr Lys Asn Leu Asp Ser Leu Glu Glu 
145                 150                 155                 160 


Asp Leu Asp Phe Leu Arg Asp Gln Phe Thr Thr Thr Glu Val Asn Met 
                165                 170                 175     


Ala Arg Val Tyr Asn Trp Asp Val Lys Arg Arg Asn Lys Asp Asp Ser 
            180                 185                 190         


Thr Lys Asn Lys Ala 
        195         


<210>  3459
<211>  779
<212>  PRT
<213>  homo sapiens

<400>  3459

Met Thr Pro Glu Phe Asp Glu Glu Val Val Phe Glu Asn Ser Pro Leu 
1               5                   10                  15      


Tyr Gln Tyr Leu Gln Asp Leu Gly His Thr Asp Phe Glu Ile Cys Ser 
            20                  25                  30          


Ser Leu Ser Pro Lys Thr Glu Lys Cys Thr Thr Glu Gly Gln Gln Lys 
        35                  40                  45              


Pro Pro Thr Arg Val Leu Pro Lys Gln Gly Ile Leu Leu Lys Val Ala 
    50                  55                  60                  


Glu Thr Ile Lys Ser Trp Ile Phe Phe Ser Gln Cys Asn Lys Lys Asp 
65                  70                  75                  80  


Asp Leu Leu His Lys Leu Asp Ile Gly Phe Arg Leu Asp Ser Leu His 
                85                  90                  95      


Thr Ile Leu Gln Gln Glu Val Leu Leu Gln Glu Asp Val Glu Leu Ile 
            100                 105                 110         


Glu Leu Leu Asp Pro Ser Ile Leu Ser Ala Gly Gln Ser Gln Gln Gln 
        115                 120                 125             


Glu Asn Gly His Leu Pro Thr Leu Cys Ser Leu Ala Thr Pro Asn Ile 
    130                 135                 140                 


Trp Asp Leu Ser Met Leu Phe Ala Phe Ile Ser Leu Leu Val Met Leu 
145                 150                 155                 160 


Pro Thr Trp Trp Ile Val Ser Ser Trp Leu Val Trp Gly Val Ile Leu 
                165                 170                 175     


Phe Val Tyr Leu Val Ile Arg Ala Leu Arg Leu Trp Arg Thr Ala Lys 
            180                 185                 190         


Leu Gln Val Thr Leu Lys Lys Tyr Ser Val His Leu Glu Asp Met Ala 
        195                 200                 205             


Thr Asn Ser Arg Ala Phe Thr Asn Leu Val Arg Lys Ala Leu Arg Leu 
    210                 215                 220                 


Ile Gln Glu Thr Glu Val Ile Ser Arg Gly Phe Thr Leu Val Ser Ala 
225                 230                 235                 240 


Ala Cys Pro Phe Asn Lys Ala Gly Gln His Pro Ser Gln His Leu Ile 
                245                 250                 255     


Gly Leu Arg Lys Ala Val Tyr Arg Thr Leu Arg Ala Asn Phe Gln Ala 
            260                 265                 270         


Ala Arg Leu Ala Thr Leu Tyr Met Leu Lys Asn Tyr Pro Leu Asn Ser 
        275                 280                 285             


Glu Ser Asp Asn Val Thr Asn Tyr Ile Cys Val Val Pro Phe Lys Glu 
    290                 295                 300                 


Leu Gly Leu Gly Leu Ser Glu Glu Gln Ile Ser Glu Glu Glu Ala His 
305                 310                 315                 320 


Asn Phe Thr Asp Gly Phe Ser Leu Pro Ala Leu Lys Val Leu Phe Gln 
                325                 330                 335     


Leu Trp Val Ala Gln Ser Ser Glu Phe Phe Arg Arg Leu Ala Leu Leu 
            340                 345                 350         


Leu Ser Thr Ala Asn Ser Pro Pro Gly Pro Leu Leu Thr Pro Ala Leu 
        355                 360                 365             


Leu Pro His Arg Ile Leu Ser Asp Val Thr Gln Gly Leu Pro His Ala 
    370                 375                 380                 


His Ser Ala Cys Leu Glu Glu Leu Lys Arg Ser Tyr Glu Phe Tyr Arg 
385                 390                 395                 400 


Tyr Phe Glu Thr Gln His Gln Ser Val Pro Gln Cys Leu Ser Lys Thr 
                405                 410                 415     


Gln Gln Lys Ser Arg Glu Leu Asn Asn Val His Thr Ala Val Arg Ser 
            420                 425                 430         


Leu Gln Leu His Leu Lys Ala Leu Leu Asn Glu Val Ile Ile Leu Glu 
        435                 440                 445             


Asp Glu Leu Glu Lys Leu Val Cys Thr Lys Glu Thr Gln Glu Leu Val 
    450                 455                 460                 


Ser Glu Ala Tyr Pro Ile Leu Glu Gln Lys Leu Lys Leu Ile Gln Pro 
465                 470                 475                 480 


His Val Gln Ala Ser Asn Asn Cys Trp Glu Glu Ala Ile Ser Gln Val 
                485                 490                 495     


Asp Lys Leu Leu Arg Arg Asn Thr Asp Lys Lys Gly Lys Pro Glu Ile 
            500                 505                 510         


Ala Cys Glu Asn Pro His Cys Thr Val Val Pro Leu Lys Gln Pro Thr 
        515                 520                 525             


Leu His Ile Ala Asp Lys Asp Pro Ile Pro Glu Glu Gln Glu Leu Glu 
    530                 535                 540                 


Ala Tyr Val Asp Asp Ile Asp Ile Asp Ser Asp Phe Arg Lys Asp Asp 
545                 550                 555                 560 


Phe Tyr Tyr Leu Ser Gln Glu Asp Lys Glu Arg Gln Lys Arg Glu His 
                565                 570                 575     


Glu Glu Ser Lys Arg Val Leu Gln Glu Leu Lys Ser Val Leu Gly Phe 
            580                 585                 590         


Lys Ala Ser Glu Ala Glu Arg Gln Lys Trp Lys Gln Leu Leu Phe Ser 
        595                 600                 605             


Asp His Ala Val Leu Lys Ser Leu Ser Pro Val Asp Pro Val Glu Pro 
    610                 615                 620                 


Ile Ser Asn Ser Glu Pro Ser Met Asn Ser Asp Met Gly Lys Val Ser 
625                 630                 635                 640 


Lys Asn Asp Thr Glu Glu Glu Ser Asn Lys Ser Ala Thr Thr Asp Asn 
                645                 650                 655     


Glu Ile Ser Arg Thr Glu Tyr Leu Cys Glu Asn Ser Leu Glu Gly Lys 
            660                 665                 670         


Asn Lys Asp Asn Ser Ser Asn Glu Val Phe Pro Gln Gly Ala Glu Glu 
        675                 680                 685             


Arg Met Cys Tyr Gln Cys Glu Ser Glu Asp Glu Pro Gln Ala Asp Gly 
    690                 695                 700                 


Ser Gly Leu Thr Thr Ala Pro Pro Thr Pro Arg Asp Ser Leu Gln Pro 
705                 710                 715                 720 


Ser Ile Lys Gln Arg Leu Ala Arg Leu Gln Leu Ser Pro Asp Phe Thr 
                725                 730                 735     


Phe Thr Ala Gly Leu Ala Ala Glu Val Ala Ala Arg Ser Leu Ser Phe 
            740                 745                 750         


Thr Thr Met Gln Glu Gln Thr Phe Gly Gly Glu Glu Glu Glu Gln Ile 
        755                 760                 765             


Ile Glu Glu Asn Lys Asn Glu Ile Glu Glu Lys 
    770                 775                 


<210>  3460
<211>  3997
<212>  PRT
<213>  homo sapiens

<400>  3460

Met Leu Glu Ser Tyr Val Thr Pro Ile Leu Met Ser Tyr Val Asn Arg 
1               5                   10                  15      


Tyr Ile Lys Asn Leu Lys Pro Ser Asp Leu Gln Leu Ser Leu Trp Gly 
            20                  25                  30          


Gly Asp Val Val Leu Ser Lys Leu Glu Leu Lys Leu Asp Val Leu Glu 
        35                  40                  45              


Gln Glu Leu Lys Leu Pro Phe Thr Phe Leu Ser Gly His Ile His Glu 
    50                  55                  60                  


Leu Arg Ile His Val Pro Trp Thr Lys Leu Gly Ser Glu Pro Val Val 
65                  70                  75                  80  


Ile Thr Ile Asn Thr Met Glu Cys Ile Leu Lys Leu Lys Asp Gly Ile 
                85                  90                  95      


Gln Asp Asp His Glu Ser Cys Gly Ser Asn Ser Thr Asn Arg Ser Thr 
            100                 105                 110         


Ala Glu Ser Thr Lys Ser Ser Ile Lys Pro Arg Arg Met Gln Gln Ala 
        115                 120                 125             


Ala Pro Thr Asp Pro Asp Leu Pro Pro Gly Tyr Val Gln Ser Leu Ile 
    130                 135                 140                 


Arg Arg Val Val Asn Asn Val Asn Ile Val Ile Asn Asn Leu Ile Leu 
145                 150                 155                 160 


Lys Tyr Val Glu Asp Asp Ile Val Leu Ser Val Asn Ile Thr Ser Ala 
                165                 170                 175     


Glu Cys Tyr Thr Val Gly Glu Leu Trp Asp Arg Ala Phe Met Asp Ile 
            180                 185                 190         


Ser Ala Thr Asp Leu Val Leu Arg Lys Val Ile Asn Phe Ser Asp Cys 
        195                 200                 205             


Thr Val Cys Leu Asp Lys Arg Asn Ala Ser Gly Lys Ile Glu Phe Tyr 
    210                 215                 220                 


Gln Asp Pro Leu Leu Tyr Lys Cys Ser Phe Arg Thr Arg Leu His Phe 
225                 230                 235                 240 


Thr Tyr Glu Asn Leu Asn Ser Lys Met Pro Ser Val Ile Lys Ile His 
                245                 250                 255     


Thr Leu Val Glu Ser Leu Lys Leu Ser Ile Thr Asp Gln Gln Leu Pro 
            260                 265                 270         


Met Phe Ile Arg Ile Met Gln Leu Gly Ile Ala Leu Tyr Tyr Gly Glu 
        275                 280                 285             


Ile Gly Asn Phe Lys Glu Gly Glu Ile Glu Asp Leu Thr Cys His Asn 
    290                 295                 300                 


Lys Asp Met Leu Gly Asn Ile Thr Gly Ser Glu Asp Glu Thr Arg Ile 
305                 310                 315                 320 


Asp Met Gln Tyr Pro Ala Gln His Lys Gly Gln Glu Leu Tyr Ser Gln 
                325                 330                 335     


Gln Asp Glu Glu Gln Pro Gln Gly Trp Val Ser Trp Ala Trp Ser Phe 
            340                 345                 350         


Val Pro Ala Ile Val Ser Tyr Asp Asp Gly Glu Glu Asp Phe Val Gly 
        355                 360                 365             


Asn Asp Pro Ala Ser Thr Met His Gln Gln Lys Ala Gln Thr Leu Lys 
    370                 375                 380                 


Asp Pro Ile Val Ser Ile Gly Phe Tyr Cys Thr Lys Ala Thr Val Thr 
385                 390                 395                 400 


Phe Lys Leu Thr Glu Met Gln Val Glu Ser Ser Tyr Tyr Ser Pro Gln 
                405                 410                 415     


Lys Val Lys Ser Lys Glu Val Leu Cys Trp Glu Gln Glu Gly Thr Thr 
            420                 425                 430         


Val Glu Ala Leu Met Met Gly Glu Pro Phe Phe Asp Cys Gln Ile Gly 
        435                 440                 445             


Phe Val Gly Cys Arg Ala Met Cys Leu Lys Gly Ile Met Gly Val Lys 
    450                 455                 460                 


Asp Phe Glu Glu Asn Met Asn Arg Ser Glu Thr Glu Ala Cys Phe Phe 
465                 470                 475                 480 


Ile Cys Gly Asp Asn Leu Ser Thr Lys Gly Phe Thr Tyr Leu Thr Asn 
                485                 490                 495     


Ser Leu Phe Asp Tyr Arg Ser Pro Glu Asn Asn Gly Thr Arg Ala Glu 
            500                 505                 510         


Phe Ile Leu Asp Ser Thr His His Lys Glu Thr Tyr Thr Glu Ile Ala 
        515                 520                 525             


Gly Met Gln Arg Phe Gly Ala Phe Tyr Met Asp Tyr Leu Tyr Thr Met 
    530                 535                 540                 


Glu Asn Thr Ser Gly Lys Gly Ser Thr Asn Gln Gln Asp Phe Ser Ser 
545                 550                 555                 560 


Gly Lys Ser Glu Asp Leu Gly Thr Val Gln Glu Lys Ser Thr Lys Ser 
                565                 570                 575     


Leu Val Ile Gly Pro Leu Asp Phe Arg Leu Asp Ser Ser Ala Val His 
            580                 585                 590         


Arg Ile Leu Lys Met Ile Val Cys Ala Leu Glu His Glu Tyr Glu Pro 
        595                 600                 605             


Tyr Ser Arg Leu Lys Ser Asp Ile Lys Asp Glu Asn Glu Thr Ile Leu 
    610                 615                 620                 


Asn Pro Glu Glu Val Ala Leu Leu Glu Glu Tyr Ile Pro Thr Arg His 
625                 630                 635                 640 


Thr Ser Val Thr Leu Leu Lys Cys Thr Cys Thr Ile Ser Met Ala Glu 
                645                 650                 655     


Phe Asn Leu Leu Asp His Leu Leu Pro Val Ile Met Gly Glu Lys Asn 
            660                 665                 670         


Ser Ser Asn Phe Met Asn Thr Thr Asn Phe Gln Ser Leu Arg Pro Leu 
        675                 680                 685             


Pro Ser Ile Arg Ile Leu Val Asp Lys Ile Asn Leu Glu His Ser Val 
    690                 695                 700                 


Pro Met Tyr Ala Glu Gln Leu Val His Val Val Ser Ser Leu Thr Gln 
705                 710                 715                 720 


Pro Ser Asp Asn Leu Leu His Tyr Cys Tyr Val His Cys Tyr Leu Lys 
                725                 730                 735     


Ile Phe Gly Phe Gln Ala Gly Leu Thr Ser Leu Asp Cys Ser Gly Ser 
            740                 745                 750         


Tyr Cys Leu Pro Val Pro Val Ile Pro Ser Phe Ser Thr Ala Leu Tyr 
        755                 760                 765             


Gly Lys Leu Leu Lys Leu Pro Thr Cys Trp Thr Lys Arg Ser Gln Ile 
    770                 775                 780                 


Ala Ile Thr Glu Gly Ile Phe Glu Leu Pro Asn Leu Thr Ile Gln Ala 
785                 790                 795                 800 


Thr Arg Ala Gln Thr Leu Leu Leu Gln Ala Ile Tyr Gln Ser Trp Ser 
                805                 810                 815     


His Leu Gly Asn Val Ser Ser Ser Ala Val Ile Glu Ala Leu Ile Asn 
            820                 825                 830         


Glu Ile Phe Leu Ser Ile Gly Val Lys Ser Lys Asn Pro Leu Pro Thr 
        835                 840                 845             


Leu Glu Gly Ser Ile Gln Asn Val Glu Leu Lys Tyr Cys Ser Thr Ser 
    850                 855                 860                 


Leu Val Lys Cys Ala Ser Gly Thr Met Gly Ser Ile Lys Ile Cys Ala 
865                 870                 875                 880 


Lys Ala Pro Val Asp Ser Gly Lys Glu Lys Leu Ile Pro Leu Leu Gln 
                885                 890                 895     


Gly Pro Ser Asp Thr Lys Asp Leu His Ser Thr Lys Trp Leu Asn Glu 
            900                 905                 910         


Ser Arg Lys Pro Glu Ser Leu Leu Ala Pro Asp Leu Met Ala Phe Thr 
        915                 920                 925             


Ile Gln Val Pro Gln Tyr Ile Asp Tyr Cys His Asn Ser Gly Ala Val 
    930                 935                 940                 


Leu Leu Cys Ser Ile Gln Gly Leu Ala Val Asn Ile Asp Pro Ile Leu 
945                 950                 955                 960 


Tyr Thr Trp Leu Ile Tyr Gln Pro Gln Lys Arg Thr Ser Arg His Met 
                965                 970                 975     


Gln Gln Gln Pro Val Val Ala Val Pro Leu Val Met Pro Val Cys Arg 
            980                 985                 990         


Arg Lys Glu Asp Glu Val Ser Ile  Gly Ser Ala Pro Leu  Ala Lys Gln 
        995                 1000                 1005             


Gln Ser  Tyr Gln Ala Ser Glu  Tyr Ala Ser Ser Pro  Val Lys Thr 
    1010                 1015                 1020             


Lys Thr  Val Thr Glu Ser Arg  Pro Leu Ser Val Pro  Val Lys Ala 
    1025                 1030                 1035             


Met Leu  Asn Ile Ser Glu Ser  Cys Arg Ser Pro Glu  Glu Arg Met 
    1040                 1045                 1050             


Lys Glu  Phe Ile Gly Ile Val  Trp Asn Ala Val Lys  His Leu Thr 
    1055                 1060                 1065             


Leu Gln  Leu Glu Val Gln Ser  Cys Cys Val Phe Ile  Pro Asn Asp 
    1070                 1075                 1080             


Ser Leu  Pro Ser Pro Ser Thr  Ile Val Ser Gly Asp  Ile Pro Gly 
    1085                 1090                 1095             


Thr Val  Arg Ser Trp Tyr His  Gly Gln Thr Ser Met  Pro Gly Thr 
    1100                 1105                 1110             


Leu Val  Leu Cys Leu Pro Gln  Ile Lys Ile Ile Ser  Ala Gly His 
    1115                 1120                 1125             


Lys Tyr  Met Glu Pro Leu Gln  Glu Ile Pro Phe Val  Ile Pro Arg 
    1130                 1135                 1140             


Pro Ile  Leu Glu Glu Gly Asp  Ala Phe Pro Trp Thr  Ile Ser Leu 
    1145                 1150                 1155             


His Asn  Phe Ser Ile Tyr Thr  Leu Leu Gly Lys Gln  Val Thr Leu 
    1160                 1165                 1170             


Cys Leu  Val Glu Pro Met Gly  Cys Thr Ser Thr Leu  Ala Val Thr 
    1175                 1180                 1185             


Ser Gln  Lys Leu Leu Ala Thr  Gly Pro Asp Thr Arg  His Ser Phe 
    1190                 1195                 1200             


Val Val  Cys Leu His Val Asp  Leu Glu Ser Leu Glu  Ile Lys Cys 
    1205                 1210                 1215             


Ser Asn  Pro Gln Val Gln Leu  Phe Tyr Glu Leu Thr  Asp Ile Met 
    1220                 1225                 1230             


Asn Lys  Val Trp Asn Lys Ile  Gln Lys Arg Gly Asn  Leu Asn Leu 
    1235                 1240                 1245             


Ser Pro  Thr Ser Pro Glu Thr  Met Ala Gly Pro Val  Pro Thr Ser 
    1250                 1255                 1260             


Pro Val  Arg Ser Ser Ile Gly  Thr Ala Pro Pro Asp  Thr Ser Thr 
    1265                 1270                 1275             


Cys Ser  Pro Ser Ala Asp Ile  Gly Thr Thr Thr Glu  Gly Asp Ser 
    1280                 1285                 1290             


Ile Gln  Ala Gly Glu Glu Ser  Pro Phe Ser Asp Ser  Val Thr Leu 
    1295                 1300                 1305             


Glu Gln  Thr Thr Ser Asn Ile  Gly Gly Thr Ser Gly  Arg Val Ser 
    1310                 1315                 1320             


Leu Trp  Met Gln Trp Val Leu  Pro Lys Ile Thr Ile  Lys Leu Phe 
    1325                 1330                 1335             


Ala Pro  Asp Pro Glu Asn Lys  Gly Thr Glu Val Cys  Met Val Ser 
    1340                 1345                 1350             


Glu Leu  Glu Asp Leu Ser Ala  Ser Ile Asp Val Gln  Asp Val Tyr 
    1355                 1360                 1365             


Thr Lys  Val Lys Cys Lys Ile  Glu Ser Phe Asn Ile  Asp His Tyr 
    1370                 1375                 1380             


Arg Ser  Arg Pro Gly Glu Gly  Trp Gln Ser Gly His  Phe Glu Gly 
    1385                 1390                 1395             


Val Phe  Leu Gln Cys Lys Glu  Lys Ser Val Thr Thr  Thr Lys Leu 
    1400                 1405                 1410             


Leu Asp  Gly Thr His Gln Gln  His Gly Phe Leu Ser  Leu Thr Tyr 
    1415                 1420                 1425             


Thr Lys  Ala Val Thr Lys Asn  Val Arg His Lys Leu  Thr Ser Arg 
    1430                 1435                 1440             


Asn Glu  Arg Arg Ser Phe His  Lys Leu Ser Glu Gly  Leu Met Asp 
    1445                 1450                 1455             


Gly Ser  Pro His Phe Leu His  Glu Ile Leu Leu Ser  Ala Gln Ala 
    1460                 1465                 1470             


Phe Asp  Ile Val Leu Tyr Phe  Pro Leu Leu Asn Ala  Ile Ala Ser 
    1475                 1480                 1485             


Ile Phe  Gln Ala Lys Leu Pro  Lys Thr Gln Lys Glu  Lys Arg Lys 
    1490                 1495                 1500             


Ser Pro  Gly Gln Pro Met Arg  Thr His Thr Leu Thr  Ser Arg Asn 
    1505                 1510                 1515             


Leu Pro  Leu Ile Tyr Val Asn  Thr Ser Val Ile Arg  Ile Phe Ile 
    1520                 1525                 1530             


Pro Lys  Thr Glu Glu Met Gln  Pro Thr Val Glu Ala  Asn Gln Ala 
    1535                 1540                 1545             


Ala Lys  Glu Asp Thr Val Val  Leu Lys Ile Gly Ser  Val Ala Met 
    1550                 1555                 1560             


Ala Pro  Gln Ala Asp Asn Pro  Leu Gly Arg Ser Val  Leu Arg Lys 
    1565                 1570                 1575             


Asp Ile  Tyr Gln Arg Ala Leu  Asn Leu Gly Ile Leu  Arg Asp Pro 
    1580                 1585                 1590             


Gly Ser  Glu Ile Glu Asp Arg  Gln Tyr Gln Ile Asp  Leu Gln Ser 
    1595                 1600                 1605             


Ile Asn  Ile Gly Thr Ala Gln  Trp His Gln Leu Lys  Pro Glu Lys 
    1610                 1615                 1620             


Glu Ser  Val Ser Gly Gly Val  Val Thr Glu Thr Glu  Arg Asn Ser 
    1625                 1630                 1635             


Gln Asn  Pro Ala Leu Glu Trp  Asn Met Ala Ser Ser  Ile Arg Arg 
    1640                 1645                 1650             


His Gln  Glu Arg Arg Ala Ile  Leu Thr Pro Val Leu  Thr Asp Phe 
    1655                 1660                 1665             


Ser Val  Arg Ile Thr Gly Ala  Pro Ala Val Ile Phe  Thr Lys Val 
    1670                 1675                 1680             


Val Ser  Pro Glu Asn Leu His  Thr Glu Glu Ile Leu  Val Cys Gly 
    1685                 1690                 1695             


His Ser  Leu Glu Val Asn Ile  Thr Thr Asn Leu Asp  Phe Phe Leu 
    1700                 1705                 1710             


Ser Val  Ala Gln Val Gln Leu  Leu His Gln Leu Ile  Val Ala Asn 
    1715                 1720                 1725             


Met Thr  Gly Leu Glu Pro Ser  Asn Lys Ala Ala Glu  Ile Ser Lys 
    1730                 1735                 1740             


Gln Glu  Gln Lys Lys Val Asp  Ile Phe Asp Gly Gly  Met Ala Glu 
    1745                 1750                 1755             


Thr Ser  Ser Arg Tyr Ser Gly  Ala Gln Asp Ser Gly  Ile Gly Ser 
    1760                 1765                 1770             


Asp Ser  Val Lys Ile Arg Ile  Val Gln Ile Glu Gln  His Ser Gly 
    1775                 1780                 1785             


Ala Ser  Gln His Arg Ile Ala  Arg Pro Ser Arg Gln  Ser Ser Ile 
    1790                 1795                 1800             


Val Lys  Asn Leu Asn Phe Ile  Pro Phe Asp Ile Phe  Ile Thr Ala 
    1805                 1810                 1815             


Ser Arg  Ile Ser Leu Met Thr  Tyr Ser Cys Met Ala  Leu Ser Lys 
    1820                 1825                 1830             


Ser Lys  Ser Gln Glu Gln Lys  Asn Asn Glu Lys Thr  Asp Lys Ser 
    1835                 1840                 1845             


Ser Leu  Asn Leu Pro Glu Val  Asp Ser Asp Val Ala  Lys Pro Asn 
    1850                 1855                 1860             


Gln Ala  Cys Ile Ser Thr Val  Thr Ala Glu Asp Leu  Leu Arg Ser 
    1865                 1870                 1875             


Ser Ile  Ser Phe Pro Ser Gly  Lys Lys Ile Gly Val  Leu Ser Leu 
    1880                 1885                 1890             


Glu Ser  Leu His Ala Ser Thr  Arg Ser Ser Ala Arg  Gln Ala Leu 
    1895                 1900                 1905             


Gly Ile  Thr Ile Val Arg Gln  Pro Gly Arg Arg Gly  Thr Gly Asp 
    1910                 1915                 1920             


Leu Gln  Leu Glu Pro Phe Leu  Tyr Phe Ile Val Ser  Gln Pro Ser 
    1925                 1930                 1935             


Leu Leu  Leu Ser Cys His His  Arg Lys Gln Arg Val  Glu Val Ser 
    1940                 1945                 1950             


Ile Phe  Asp Ala Val Leu Lys  Gly Val Ala Ser Asp  Tyr Lys Cys 
    1955                 1960                 1965             


Ile Asp  Pro Gly Lys Thr Leu  Pro Glu Ala Leu Asp  Tyr Cys Thr 
    1970                 1975                 1980             


Val Trp  Leu Gln Thr Val Pro  Gly Glu Ile Asp Ser  Lys Ser Gly 
    1985                 1990                 1995             


Ile Pro  Pro Ser Phe Ile Thr  Leu Gln Ile Lys Asp  Phe Leu Asn 
    2000                 2005                 2010             


Gly Pro  Ala Asp Val Asn Leu  Asp Ile Ser Lys Pro  Leu Lys Ala 
    2015                 2020                 2025             


Asn Leu  Ser Phe Thr Lys Leu  Asp Gln Ile Asn Leu  Phe Leu Lys 
    2030                 2035                 2040             


Lys Ile  Lys Asn Ala His Ser  Leu Ala His Ser Glu  Glu Thr Ser 
    2045                 2050                 2055             


Ala Met  Ser Asn Thr Met Val  Asn Lys Asp Asp Leu  Pro Val Ser 
    2060                 2065                 2070             


Lys Tyr  Tyr Arg Gly Lys Leu  Ser Lys Pro Lys Ile  His Gly Asp 
    2075                 2080                 2085             


Gly Val  Gln Lys Ile Ser Ala  Gln Glu Asn Met Trp  Arg Ala Val 
    2090                 2095                 2100             


Ser Cys  Phe Gln Lys Ile Ser  Val Gln Thr Thr Gln  Ile Val Ile 
    2105                 2110                 2115             


Ser Met  Glu Thr Val Pro His  Thr Ser Lys Pro Cys  Leu Leu Ala 
    2120                 2125                 2130             


Ser Leu  Ser Asn Leu Asn Gly  Ser Leu Ser Val Lys  Ala Thr Gln 
    2135                 2140                 2145             


Lys Val  Pro Gly Ile Ile Leu  Gly Ser Ser Phe Leu  Leu Ser Ile 
    2150                 2155                 2160             


Asn Asp  Phe Leu Leu Lys Thr  Ser Leu Lys Glu Arg  Ser Arg Ile 
    2165                 2170                 2175             


Leu Ile  Gly Pro Cys Cys Ala  Thr Ala Asn Leu Glu  Ala Lys Trp 
    2180                 2185                 2190             


Cys Lys  His Ser Gly Asn Pro  Gly Pro Glu Gln Ser  Ile Pro Lys 
    2195                 2200                 2205             


Ile Ser  Ile Asp Leu Arg Gly  Gly Leu Leu Gln Val  Phe Trp Gly 
    2210                 2215                 2220             


Gln Glu  His Leu Asn Cys Leu  Val Leu Leu His Glu  Leu Leu Asn 
    2225                 2230                 2235             


Gly Tyr  Leu Asn Glu Glu Gly  Asn Phe Glu Val Gln  Val Ser Glu 
    2240                 2245                 2250             


Pro Val  Pro Gln Met Ser Ser  Pro Val Glu Lys Asn  Gln Thr Phe 
    2255                 2260                 2265             


Lys Ser  Glu Gln Ser Ser Asp  Asp Leu Arg Thr Gly  Leu Phe Gln 
    2270                 2275                 2280             


Tyr Val  Gln Asp Ala Glu Ser  Leu Lys Leu Pro Gly  Val Tyr Glu 
    2285                 2290                 2295             


Val Leu  Phe Tyr Asn Glu Thr  Glu Asp Cys Pro Gly  Met Met Leu 
    2300                 2305                 2310             


Trp Arg  Tyr Pro Glu Pro Arg  Val Leu Thr Leu Val  Arg Ile Thr 
    2315                 2320                 2325             


Pro Val  Pro Phe Asn Thr Thr  Glu Asp Pro Asp Ile  Ser Thr Ala 
    2330                 2335                 2340             


Asp Leu  Gly Asp Val Leu Gln  Val Pro Cys Ser Leu  Glu Tyr Trp 
    2345                 2350                 2355             


Asp Glu  Leu Gln Lys Val Phe  Val Ala Phe Arg Glu  Phe Asn Leu 
    2360                 2365                 2370             


Ser Glu  Ser Lys Val Cys Glu  Leu Gln Leu Pro Asp  Ile Asn Leu 
    2375                 2380                 2385             


Val Asn  Asp Gln Lys Lys Leu  Val Ser Ser Asp Leu  Trp Arg Ile 
    2390                 2395                 2400             


Val Leu  Asn Ser Ser Gln Asn  Gly Ala Asp Asp Gln  Ser Ser Ala 
    2405                 2410                 2415             


Ser Glu  Ser Gly Ser Gln Ser  Thr Cys Asp Pro Leu  Val Thr Pro 
    2420                 2425                 2430             


Thr Ala  Leu Ala Ala Cys Thr  Arg Val Asp Ser Cys  Phe Thr Pro 
    2435                 2440                 2445             


Trp Phe  Val Pro Ser Leu Cys  Val Ser Phe Gln Phe  Ala His Leu 
    2450                 2455                 2460             


Glu Phe  His Leu Cys His His  Leu Asp Gln Leu Gly  Thr Ala Ala 
    2465                 2470                 2475             


Pro Gln  Tyr Leu Gln Pro Phe  Val Ser Asp Arg Asn  Met Pro Ser 
    2480                 2485                 2490             


Glu Leu  Glu Tyr Met Ile Val  Ser Phe Arg Glu Pro  His Met Tyr 
    2495                 2500                 2505             


Leu Arg  Gln Trp Asn Asn Gly  Ser Val Cys Gln Glu  Ile Gln Phe 
    2510                 2515                 2520             


Leu Ala  Gln Ala Asp Cys Lys  Leu Leu Glu Cys Arg  Asn Val Thr 
    2525                 2530                 2535             


Met Gln  Ser Val Val Lys Pro  Phe Ser Ile Phe Gly  Gln Met Ala 
    2540                 2545                 2550             


Val Ser  Ser Asp Val Val Glu  Lys Leu Leu Asp Cys  Thr Val Ile 
    2555                 2560                 2565             


Val Asp  Ser Val Phe Val Asn  Leu Gly Gln His Val  Val His Ser 
    2570                 2575                 2580             


Leu Asn  Thr Ala Ile Gln Ala  Trp Gln Gln Asn Lys  Cys Pro Glu 
    2585                 2590                 2595             


Val Glu  Glu Leu Val Phe Ser  His Phe Val Ile Cys  Asn Asp Thr 
    2600                 2605                 2610             


Gln Glu  Thr Leu Arg Phe Gly  Gln Val Asp Thr Asp  Glu Asn Ile 
    2615                 2620                 2625             


Leu Leu  Ala Ser Leu His Ser  His Gln Tyr Ser Trp  Arg Ser His 
    2630                 2635                 2640             


Lys Ser  Pro Gln Leu Leu His  Ile Cys Ile Glu Gly  Trp Gly Asn 
    2645                 2650                 2655             


Trp Arg  Trp Ser Glu Pro Phe  Ser Val Asp His Ala  Gly Thr Phe 
    2660                 2665                 2670             


Ile Arg  Thr Ile Gln Tyr Arg  Gly Arg Thr Ala Ser  Leu Ile Ile 
    2675                 2680                 2685             


Lys Val  Gln Gln Leu Asn Gly  Val Gln Lys Gln Ile  Ile Ile Cys 
    2690                 2695                 2700             


Gly Arg  Gln Ile Ile Cys Ser  Tyr Leu Ser Gln Ser  Ile Glu Leu 
    2705                 2710                 2715             


Lys Val  Val Gln His Tyr Ile  Gly Gln Asp Gly Gln  Ala Val Val 
    2720                 2725                 2730             


Arg Glu  His Phe Asp Cys Leu  Thr Ala Lys Gln Lys  Leu Pro Ser 
    2735                 2740                 2745             


Tyr Ile  Leu Glu Asn Asn Glu  Leu Thr Glu Leu Cys  Val Lys Ala 
    2750                 2755                 2760             


Lys Gly  Asp Glu Asp Trp Ser  Arg Asp Val Cys Leu  Glu Ser Lys 
    2765                 2770                 2775             


Ala Pro  Glu Tyr Ser Ile Val  Ile Gln Val Pro Ser  Ser Asn Ser 
    2780                 2785                 2790             


Ser Ile  Ile Tyr Val Trp Cys  Thr Val Leu Thr Leu  Glu Pro Asn 
    2795                 2800                 2805             


Ser Gln  Val Gln Gln Arg Met  Ile Val Phe Ser Pro  Leu Phe Ile 
    2810                 2815                 2820             


Met Arg  Ser His Leu Pro Asp  Pro Ile Ile Ile His  Leu Glu Lys 
    2825                 2830                 2835             


Arg Ser  Leu Gly Leu Ser Glu  Thr Gln Ile Ile Pro  Gly Lys Gly 
    2840                 2845                 2850             


Gln Glu  Lys Pro Leu Gln Asn  Ile Glu Pro Asp Leu  Val His His 
    2855                 2860                 2865             


Leu Thr  Phe Gln Ala Arg Glu  Glu Tyr Asp Pro Ser  Asp Cys Ala 
    2870                 2875                 2880             


Val Pro  Ile Ser Thr Ser Leu  Ile Lys Gln Ile Ala  Thr Lys Val 
    2885                 2890                 2895             


His Pro  Gly Gly Thr Val Asn  Gln Ile Leu Asp Glu  Phe Tyr Gly 
    2900                 2905                 2910             


Pro Glu  Lys Ser Leu Gln Pro  Ile Trp Pro Tyr Asn  Lys Lys Asp 
    2915                 2920                 2925             


Ser Asp  Arg Asn Glu Gln Leu  Ser Gln Trp Asp Ser  Pro Met Arg 
    2930                 2935                 2940             


Val Lys  Leu Ser Ile Trp Lys  Pro Tyr Val Arg Thr  Leu Leu Ile 
    2945                 2950                 2955             


Glu Leu  Leu Pro Trp Ala Leu  Leu Ile Asn Glu Ser  Lys Trp Asp 
    2960                 2965                 2970             


Leu Trp  Leu Phe Glu Gly Glu  Lys Ile Val Leu Gln  Val Pro Ala 
    2975                 2980                 2985             


Gly Lys  Ile Ile Ile Pro Pro  Asn Phe Gln Glu Ala  Phe Gln Ile 
    2990                 2995                 3000             


Gly Ile  Tyr Trp Ala Asn Thr  Asn Thr Val His Lys  Ser Val Ala 
    3005                 3010                 3015             


Ile Lys  Leu Val His Asn Leu  Thr Ser Pro Lys Trp  Lys Asp Gly 
    3020                 3025                 3030             


Gly Asn  Gly Glu Val Val Thr  Leu Asp Glu Glu Ala  Phe Val Asp 
    3035                 3040                 3045             


Thr Glu  Ile Arg Leu Gly Ala  Phe Pro Gly His Gln  Lys Leu Cys 
    3050                 3055                 3060             


Gln Phe  Cys Ile Ser Ser Met  Val Gln Gln Gly Ile  Gln Ile Ile 
    3065                 3070                 3075             


Gln Ile  Glu Asp Lys Thr Thr  Ile Ile Asn Asn Thr  Pro Tyr Gln 
    3080                 3085                 3090             


Ile Phe  Tyr Lys Pro Gln Leu  Ser Val Cys Asn Pro  His Ser Gly 
    3095                 3100                 3105             


Lys Glu  Tyr Phe Arg Val Pro  Asp Ser Ala Thr Phe  Ser Ile Cys 
    3110                 3115                 3120             


Pro Gly  Gly Glu Gln Pro Ala  Met Lys Ser Ser Ser  Leu Pro Cys 
    3125                 3130                 3135             


Trp Asp  Leu Met Pro Asp Ile  Ser Gln Ser Val Leu  Asp Ala Ser 
    3140                 3145                 3150             


Leu Leu  Gln Lys Gln Ile Met  Leu Gly Phe Ser Pro  Ala Pro Gly 
    3155                 3160                 3165             


Ala Asp  Ser Ser Gln Cys Trp  Ser Leu Pro Ala Ile  Val Arg Pro 
    3170                 3175                 3180             


Glu Phe  Pro Arg Gln Ser Val  Ala Val Pro Leu Gly  Asn Phe Arg 
    3185                 3190                 3195             


Glu Asn  Gly Phe Cys Thr Arg  Ala Ile Val Leu Thr  Tyr Gln Glu 
    3200                 3205                 3210             


His Leu  Gly Val Thr Tyr Leu  Thr Leu Ser Glu Asp  Pro Ser Pro 
    3215                 3220                 3225             


Arg Val  Ile Ile His Asn Arg  Cys Pro Val Lys Met  Leu Ile Lys 
    3230                 3235                 3240             


Glu Asn  Ile Lys Asp Ile Pro  Lys Phe Glu Val Tyr  Cys Lys Lys 
    3245                 3250                 3255             


Ile Pro  Ser Glu Cys Ser Ile  His His Glu Leu Tyr  His Gln Ile 
    3260                 3265                 3270             


Ser Ser  Tyr Pro Asp Cys Lys  Thr Lys Asp Leu Leu  Pro Ser Leu 
    3275                 3280                 3285             


Leu Leu  Arg Val Glu Pro Leu  Asp Glu Val Thr Thr  Glu Trp Ser 
    3290                 3295                 3300             


Asp Ala  Ile Asp Ile Asn Ser  Gln Gly Thr Gln Val  Val Phe Leu 
    3305                 3310                 3315             


Thr Gly  Phe Gly Tyr Val Tyr  Val Asp Val Val His  Gln Cys Gly 
    3320                 3325                 3330             


Thr Val  Phe Ile Thr Val Ala  Pro Glu Gly Lys Ala  Gly Pro Ile 
    3335                 3340                 3345             


Leu Thr  Asn Thr Asn Arg Ala  Pro Glu Lys Ile Val  Thr Phe Lys 
    3350                 3355                 3360             


Met Phe  Ile Thr Gln Leu Ser  Leu Ala Val Phe Asp  Asp Leu Thr 
    3365                 3370                 3375             


His His  Lys Ala Ser Ala Glu  Leu Leu Arg Leu Thr  Leu Asp Asn 
    3380                 3385                 3390             


Ile Phe  Leu Cys Val Ala Pro  Gly Ala Gly Pro Leu  Pro Gly Glu 
    3395                 3400                 3405             


Glu Pro  Val Ala Ala Leu Phe  Glu Leu Tyr Cys Val  Glu Ile Cys 
    3410                 3415                 3420             


Cys Gly  Asp Leu Gln Leu Asp  Asn Gln Leu Tyr Asn  Lys Ser Asn 
    3425                 3430                 3435             


Phe His  Phe Ala Val Leu Val  Cys Gln Gly Glu Lys  Ala Glu Pro 
    3440                 3445                 3450             


Ile Gln  Cys Ser Lys Met Gln  Ser Leu Leu Ile Ser  Asn Lys Glu 
    3455                 3460                 3465             


Leu Glu  Glu Tyr Lys Glu Lys  Cys Phe Ile Lys Leu  Cys Ile Thr 
    3470                 3475                 3480             


Leu Asn  Glu Gly Lys Ser Ile  Leu Cys Asp Ile Asn  Glu Phe Ser 
    3485                 3490                 3495             


Phe Glu  Leu Lys Pro Ala Arg  Leu Tyr Val Glu Asp  Thr Phe Val 
    3500                 3505                 3510             


Tyr Tyr  Ile Lys Thr Leu Phe  Asp Thr Tyr Leu Pro  Asn Ser Arg 
    3515                 3520                 3525             


Leu Ala  Gly His Ser Thr His  Leu Ser Gly Gly Lys  Gln Val Leu 
    3530                 3535                 3540             


Pro Met  Gln Val Thr Gln His  Ala Arg Ala Leu Val  Asn Pro Val 
    3545                 3550                 3555             


Lys Leu  Arg Lys Leu Val Ile  Gln Pro Val Asn Leu  Leu Val Ser 
    3560                 3565                 3570             


Ile His  Ala Ser Leu Lys Leu  Tyr Ile Ala Ser Asp  His Thr Pro 
    3575                 3580                 3585             


Leu Ser  Phe Ser Val Phe Glu  Arg Gly Pro Ile Phe  Thr Thr Ala 
    3590                 3595                 3600             


Arg Gln  Leu Val His Ala Leu  Ala Met His Tyr Ala  Ala Gly Ala 
    3605                 3610                 3615             


Leu Phe  Arg Ala Gly Trp Val  Val Gly Ser Leu Asp  Ile Leu Gly 
    3620                 3625                 3630             


Ser Pro  Ala Ser Leu Val Arg  Ser Ile Gly Asn Gly  Val Ala Asp 
    3635                 3640                 3645             


Phe Phe  Arg Leu Pro Tyr Glu  Gly Leu Thr Arg Gly  Pro Gly Ala 
    3650                 3655                 3660             


Phe Val  Ser Gly Val Ser Arg  Gly Thr Thr Ser Phe  Val Lys His 
    3665                 3670                 3675             


Ile Ser  Lys Gly Thr Leu Thr  Ser Ile Thr Asn Leu  Ala Thr Ser 
    3680                 3685                 3690             


Leu Ala  Arg Asn Met Asp Arg  Leu Ser Leu Asp Glu  Glu His Tyr 
    3695                 3700                 3705             


Asn Arg  Gln Glu Glu Trp Arg  Arg Gln Leu Pro Glu  Ser Leu Gly 
    3710                 3715                 3720             


Glu Gly  Leu Arg Gln Gly Leu  Ser Arg Leu Gly Ile  Ser Leu Leu 
    3725                 3730                 3735             


Gly Ala  Ile Ala Gly Ile Val  Asp Gln Pro Met Gln  Asn Phe Gln 
    3740                 3745                 3750             


Lys Thr  Ser Glu Ala Gln Ala  Ser Ala Gly His Lys  Ala Lys Gly 
    3755                 3760                 3765             


Val Ile  Ser Gly Val Gly Lys  Gly Ile Met Gly Val  Phe Thr Lys 
    3770                 3775                 3780             


Pro Ile  Gly Gly Ala Ala Glu  Leu Val Ser Gln Thr  Gly Tyr Gly 
    3785                 3790                 3795             


Ile Leu  His Gly Ala Gly Leu  Ser Gln Leu Pro Lys  Gln Arg His 
    3800                 3805                 3810             


Gln Pro  Ser Asp Leu His Ala  Asp Gln Ala Pro Asn  Ser His Val 
    3815                 3820                 3825             


Lys Tyr  Val Trp Lys Met Leu  Gln Ser Leu Gly Arg  Pro Glu Val 
    3830                 3835                 3840             


His Met  Ala Leu Asp Val Val  Leu Val Arg Gly Ser  Gly Gln Glu 
    3845                 3850                 3855             


His Glu  Gly Cys Leu Leu Leu  Thr Ser Glu Val Leu  Phe Val Val 
    3860                 3865                 3870             


Ser Val  Ser Glu Asp Thr Gln  Gln Gln Ala Phe Pro  Val Thr Glu 
    3875                 3880                 3885             


Ile Asp  Cys Ala Gln Asp Ser  Lys Gln Asn Asn Leu  Leu Thr Val 
    3890                 3895                 3900             


Gln Leu  Lys Gln Pro Arg Val  Ala Cys Asp Val Glu  Val Asp Gly 
    3905                 3910                 3915             


Val Arg  Glu Arg Leu Ser Glu  Gln Gln Tyr Asn Arg  Leu Val Asp 
    3920                 3925                 3930             


Tyr Ile  Thr Lys Thr Ser Cys  His Leu Ala Pro Ser  Cys Ser Ser 
    3935                 3940                 3945             


Met Gln  Ile Pro Cys Pro Val  Val Ala Ala Glu Pro  Pro Pro Ser 
    3950                 3955                 3960             


Thr Val  Lys Thr Tyr His Tyr  Leu Val Asp Pro His  Phe Ala Gln 
    3965                 3970                 3975             


Val Phe  Leu Ser Lys Phe Thr  Met Val Lys Asn Lys  Ala Leu Arg 
    3980                 3985                 3990             


Lys Gly  Phe Pro 
    3995         


<210>  3461
<211>  613
<212>  PRT
<213>  homo sapiens

<400>  3461

Met Ala Arg Gln Pro Pro Pro Pro Trp Val His Ala Ala Phe Leu Leu 
1               5                   10                  15      


Cys Leu Leu Ser Leu Gly Gly Ala Ile Glu Ile Pro Met Asp Leu Thr 
            20                  25                  30          


Gln Pro Pro Thr Ile Thr Lys Gln Ser Ala Lys Asp His Ile Val Asp 
        35                  40                  45              


Pro Arg Asp Asn Ile Leu Ile Glu Cys Glu Ala Lys Gly Asn Pro Ala 
    50                  55                  60                  


Pro Ser Phe His Trp Thr Arg Asn Ser Arg Phe Phe Asn Ile Ala Lys 
65                  70                  75                  80  


Asp Pro Arg Val Ser Met Arg Arg Arg Ser Gly Thr Leu Val Ile Asp 
                85                  90                  95      


Phe Arg Ser Gly Gly Arg Pro Glu Glu Tyr Glu Gly Glu Tyr Gln Cys 
            100                 105                 110         


Phe Ala Arg Asn Lys Phe Gly Thr Ala Leu Ser Asn Arg Ile Arg Leu 
        115                 120                 125             


Gln Val Ser Lys Ser Pro Leu Trp Pro Lys Glu Asn Leu Asp Pro Val 
    130                 135                 140                 


Val Val Gln Glu Gly Ala Pro Leu Thr Leu Gln Cys Asn Pro Pro Pro 
145                 150                 155                 160 


Gly Leu Pro Ser Pro Val Ile Phe Trp Met Ser Ser Ser Met Glu Pro 
                165                 170                 175     


Ile Thr Gln Asp Lys Arg Val Ser Gln Gly His Asn Gly Asp Leu Tyr 
            180                 185                 190         


Phe Ser Asn Val Met Leu Gln Asp Met Gln Thr Asp Tyr Ser Cys Asn 
        195                 200                 205             


Ala Arg Phe His Phe Thr His Thr Ile Gln Gln Lys Asn Pro Phe Thr 
    210                 215                 220                 


Leu Lys Val Leu Thr Thr Arg Gly Val Ala Glu Arg Thr Pro Ser Phe 
225                 230                 235                 240 


Met Tyr Pro Gln Gly Thr Ala Ser Ser Gln Met Val Leu Arg Gly Met 
                245                 250                 255     


Asp Leu Leu Leu Glu Cys Ile Ala Ser Gly Val Pro Thr Pro Asp Ile 
            260                 265                 270         


Ala Trp Tyr Lys Lys Gly Gly Asp Leu Pro Ser Asp Lys Ala Lys Phe 
        275                 280                 285             


Glu Asn Phe Asn Lys Ala Leu Arg Ile Thr Asn Val Ser Glu Glu Asp 
    290                 295                 300                 


Ser Gly Glu Tyr Phe Cys Leu Ala Ser Asn Lys Met Gly Ser Ile Arg 
305                 310                 315                 320 


His Thr Ile Ser Val Arg Val Lys Ala Ala Pro Tyr Trp Leu Asp Glu 
                325                 330                 335     


Pro Lys Asn Leu Ile Leu Ala Pro Gly Glu Asp Gly Arg Leu Val Cys 
            340                 345                 350         


Arg Ala Asn Gly Asn Pro Lys Pro Thr Val Gln Trp Met Val Asn Gly 
        355                 360                 365             


Glu Pro Leu Gln Ser Ala Pro Pro Asn Pro Asn Arg Glu Val Ala Gly 
    370                 375                 380                 


Asp Thr Ile Ile Phe Arg Asp Thr Gln Ile Ser Ser Arg Ala Val Tyr 
385                 390                 395                 400 


Gln Cys Asn Thr Ser Asn Glu His Gly Tyr Leu Leu Ala Asn Ala Phe 
                405                 410                 415     


Val Ser Val Leu Asp Val Pro Pro Arg Met Leu Ser Pro Arg Asn Gln 
            420                 425                 430         


Leu Ile Arg Val Ile Leu Tyr Asn Arg Thr Arg Leu Asp Cys Pro Phe 
        435                 440                 445             


Phe Gly Ser Pro Ile Pro Thr Leu Arg Trp Phe Lys Asn Gly Gln Gly 
    450                 455                 460                 


Ser Asn Leu Asp Gly Gly Asn Tyr His Val Tyr Glu Asn Gly Ser Leu 
465                 470                 475                 480 


Glu Ile Lys Met Ile Arg Lys Glu Asp Gln Gly Ile Tyr Thr Cys Val 
                485                 490                 495     


Ala Thr Asn Ile Leu Gly Lys Ala Glu Asn Gln Val Arg Leu Glu Val 
            500                 505                 510         


Lys Asp Pro Thr Arg Ile Tyr Arg Met Pro Glu Asp Gln Val Ala Arg 
        515                 520                 525             


Arg Gly Thr Thr Val Gln Leu Glu Cys Arg Val Lys His Asp Pro Ser 
    530                 535                 540                 


Leu Lys Leu Thr Val Ser Trp Leu Lys Asp Asp Glu Pro Leu Tyr Ile 
545                 550                 555                 560 


Gly Asn Arg Met Lys Lys Glu Asp Asp Ser Leu Thr Ile Phe Gly Val 
                565                 570                 575     


Ala Glu Arg Asp Gln Gly Ser Tyr Thr Cys Val Ala Ser Thr Glu Leu 
            580                 585                 590         


Asp Gln Asp Leu Ala Lys Ala Tyr Leu Thr Val Leu Gly Asn Cys Pro 
        595                 600                 605             


Cys Ser Pro Trp His 
    610             


<210>  3462
<211>  232
<212>  PRT
<213>  homo sapiens

<400>  3462

Met Ser Ala Leu Leu Arg Leu Leu Arg Thr Gly Ala Pro Ala Ala Ala 
1               5                   10                  15      


Cys Leu Arg Leu Gly Thr Ser Ala Gly Thr Gly Ser Arg Arg Ala Met 
            20                  25                  30          


Ala Leu Tyr His Thr Glu Glu Arg Gly Gln Pro Cys Ser Gln Asn Tyr 
        35                  40                  45              


Arg Leu Phe Phe Lys Asn Val Thr Gly His Tyr Ile Ser Pro Phe His 
    50                  55                  60                  


Asp Ile Pro Leu Lys Val Asn Ser Lys Glu Ile Leu Ser Cys Gly Glu 
65                  70                  75                  80  


Val Ile His Val Lys Ile Leu Gly Ile Leu Ala Leu Ile Asp Glu Gly 
                85                  90                  95      


Glu Thr Asp Trp Lys Leu Ile Ala Ile Asn Ala Asn Asp Pro Glu Ala 
            100                 105                 110         


Ser Lys Phe His Asp Ile Asp Asp Val Lys Lys Phe Lys Pro Gly Tyr 
        115                 120                 125             


Leu Glu Ala Thr Leu Asn Trp Phe Arg Leu Tyr Lys Val Pro Asp Gly 
    130                 135                 140                 


Lys Pro Glu Asn Gln Phe Ala Phe Asn Gly Glu Phe Lys Asn Lys Ala 
145                 150                 155                 160 


Phe Ala Leu Glu Val Ile Lys Ser Thr His Gln Cys Trp Lys Ala Leu 
                165                 170                 175     


Leu Met Lys Lys Cys Asn Gly Gly Ala Ile Asn Cys Thr Asn Val Gln 
            180                 185                 190         


Ile Ser Asp Ser Pro Phe Arg Cys Thr Gln Glu Glu Ala Arg Ser Leu 
        195                 200                 205             


Val Glu Ser Val Ser Ser Ser Pro Asn Lys Glu Ser Asn Glu Glu Glu 
    210                 215                 220                 


Gln Val Trp His Phe Leu Gly Lys 
225                 230         


<210>  3463
<211>  168
<212>  PRT
<213>  homo sapiens

<400>  3463

Met Ser Ala Leu Leu Arg Leu Leu Arg Thr Gly Ala Pro Ala Ala Ala 
1               5                   10                  15      


Cys Leu Arg Leu Gly Thr Ser Ala Gly Thr Gly Ser Arg Arg Ala Met 
            20                  25                  30          


Ala Leu Tyr His Thr Glu Glu Arg Gly Gln Pro Cys Ser Gln Asn Tyr 
        35                  40                  45              


Arg Leu Phe Phe Asn Ile Asp Asp Val Lys Lys Phe Lys Pro Gly Tyr 
    50                  55                  60                  


Leu Glu Ala Thr Leu Asn Trp Phe Arg Leu Tyr Lys Val Pro Asp Gly 
65                  70                  75                  80  


Lys Pro Glu Asn Gln Phe Ala Phe Asn Gly Glu Phe Lys Asn Lys Ala 
                85                  90                  95      


Phe Ala Leu Glu Val Ile Lys Ser Thr His Gln Cys Trp Lys Ala Leu 
            100                 105                 110         


Leu Met Lys Lys Cys Asn Gly Gly Ala Ile Asn Cys Thr Asn Val Gln 
        115                 120                 125             


Ile Ser Asp Ser Pro Phe Arg Cys Thr Gln Glu Glu Ala Arg Ser Leu 
    130                 135                 140                 


Val Glu Ser Val Ser Ser Ser Pro Asn Lys Glu Ser Asn Glu Glu Glu 
145                 150                 155                 160 


Gln Val Trp His Phe Leu Gly Lys 
                165             


<210>  3464
<211>  472
<212>  PRT
<213>  homo sapiens

<400>  3464

Met Gly Asp Pro Ser Lys Gln Asp Ile Leu Thr Ile Phe Lys Arg Leu 
1               5                   10                  15      


Arg Ser Val Pro Thr Asn Lys Val Cys Phe Asp Cys Gly Ala Lys Asn 
            20                  25                  30          


Pro Ser Trp Ala Ser Ile Thr Tyr Gly Val Phe Leu Cys Ile Asp Cys 
        35                  40                  45              


Ser Gly Ser His Arg Ser Leu Gly Val His Leu Ser Phe Ile Arg Ser 
    50                  55                  60                  


Thr Glu Leu Asp Ser Asn Trp Ser Trp Phe Gln Leu Arg Cys Met Gln 
65                  70                  75                  80  


Val Gly Gly Asn Ala Ser Ala Leu Trp Leu Asp Ser Cys Val Val Pro 
                85                  90                  95      


Pro Leu Ser Pro Pro Pro Lys Glu Glu Asp Phe Phe Ala Ser His Val 
            100                 105                 110         


Ser Pro Glu Val Ser Asp Thr Ala Trp Ala Ser Ala Ile Ala Glu Pro 
        115                 120                 125             


Ser Ser Leu Thr Ser Arg Pro Val Glu Thr Thr Leu Glu Asn Asn Glu 
    130                 135                 140                 


Gly Gly Gln Glu Gln Gly Pro Ser Val Glu Gly Leu Asn Val Pro Thr 
145                 150                 155                 160 


Lys Ala Thr Leu Glu Val Ser Ser Ile Ile Lys Lys Lys Pro Asn Gln 
                165                 170                 175     


Ala Lys Lys Gly Leu Gly Ala Lys Lys Gly Ser Leu Gly Ala Gln Lys 
            180                 185                 190         


Leu Ala Asn Thr Cys Phe Asn Glu Ile Glu Lys Gln Ala Gln Ala Ala 
        195                 200                 205             


Asp Lys Met Lys Glu Gln Glu Asp Leu Ala Lys Val Val Ser Lys Glu 
    210                 215                 220                 


Glu Ser Ile Val Ser Ser Leu Arg Leu Ala Tyr Lys Asp Leu Glu Ile 
225                 230                 235                 240 


Gln Met Lys Lys Asp Glu Lys Met Asn Ile Ser Gly Lys Lys Asn Val 
                245                 250                 255     


Asp Ser Asp Arg Leu Gly Met Gly Phe Gly Asn Cys Arg Ser Val Ile 
            260                 265                 270         


Ser His Ser Val Thr Ser Asp Met Gln Thr Ile Glu Gln Glu Ser Pro 
        275                 280                 285             


Ile Met Ala Lys Pro Arg Lys Lys Tyr Asn Asp Asp Ser Asp Asp Ser 
    290                 295                 300                 


Tyr Phe Thr Ser Ser Ser Ser Tyr Phe Asp Glu Pro Val Glu Leu Arg 
305                 310                 315                 320 


Ser Ser Ser Phe Ser Ser Trp Asp Asp Ser Ser Asp Ser Tyr Trp Lys 
                325                 330                 335     


Lys Glu Thr Ser Lys Asp Thr Glu Thr Val Leu Lys Thr Thr Gly Tyr 
            340                 345                 350         


Ser Asp Arg Pro Thr Ala Arg Arg Lys Pro Asp Tyr Glu Pro Val Glu 
        355                 360                 365             


Asn Thr Asp Glu Ala Gln Lys Lys Phe Gly Asn Val Lys Ala Ile Ser 
    370                 375                 380                 


Ser Asp Met Tyr Phe Gly Arg Gln Ser Gln Ala Asp Tyr Glu Thr Arg 
385                 390                 395                 400 


Ala Arg Leu Glu Arg Leu Ser Ala Ser Ser Ser Ile Ser Ser Ala Asp 
                405                 410                 415     


Leu Phe Glu Glu Pro Arg Lys Gln Pro Ala Gly Asn Tyr Ser Leu Ser 
            420                 425                 430         


Ser Val Leu Pro Asn Ala Pro Asp Met Ala Gln Phe Lys Gln Gly Val 
        435                 440                 445             


Arg Ser Val Ala Gly Lys Leu Ser Val Phe Ala Asn Gly Val Val Thr 
    450                 455                 460                 


Ser Ile Gln Asp Arg Tyr Gly Ser 
465                 470         


<210>  3465
<211>  269
<212>  PRT
<213>  homo sapiens

<400>  3465

Met Glu Arg Leu Val Ile Arg Met Pro Phe Ser His Leu Ser Thr Tyr 
1               5                   10                  15      


Ser Leu Val Trp Val Met Ala Ala Val Val Leu Cys Thr Ala Gln Val 
            20                  25                  30          


Gln Val Val Thr Gln Asp Glu Arg Glu Gln Leu Tyr Thr Pro Ala Ser 
        35                  40                  45              


Leu Lys Cys Ser Leu Gln Asn Ala Gln Glu Ala Leu Ile Val Thr Trp 
    50                  55                  60                  


Gln Lys Lys Lys Ala Val Ser Pro Glu Asn Met Val Thr Phe Ser Glu 
65                  70                  75                  80  


Asn His Gly Val Val Ile Gln Pro Ala Tyr Lys Asp Lys Ile Asn Ile 
                85                  90                  95      


Thr Gln Leu Gly Leu Gln Asn Ser Thr Ile Thr Phe Trp Asn Ile Thr 
            100                 105                 110         


Leu Glu Asp Glu Gly Cys Tyr Met Cys Leu Phe Asn Thr Phe Gly Phe 
        115                 120                 125             


Gly Lys Ile Ser Gly Thr Ala Cys Leu Thr Val Tyr Val Gln Pro Ile 
    130                 135                 140                 


Val Ser Leu His Tyr Lys Phe Ser Glu Asp His Leu Asn Ile Thr Cys 
145                 150                 155                 160 


Ser Ala Thr Ala Arg Pro Ala Pro Met Val Phe Trp Lys Val Pro Arg 
                165                 170                 175     


Ser Gly Ile Glu Asn Ser Thr Val Thr Leu Ser His Pro Asn Gly Thr 
            180                 185                 190         


Thr Ser Val Thr Ser Ile Leu His Ile Lys Asp Pro Lys Asn Gln Val 
        195                 200                 205             


Gly Lys Glu Val Ile Cys Gln Val Leu His Leu Gly Thr Val Thr Asp 
    210                 215                 220                 


Phe Lys Gln Thr Val Asn Lys Gly Tyr Trp Phe Ser Val Pro Leu Leu 
225                 230                 235                 240 


Leu Ser Ile Val Ser Leu Val Ile Leu Leu Val Leu Ile Ser Ile Leu 
                245                 250                 255     


Leu Tyr Trp Lys Arg His Arg Asn Gln Asp Arg Glu Pro 
            260                 265                 


<210>  3466
<211>  777
<212>  PRT
<213>  homo sapiens

<400>  3466

Met Asp Ser Lys Glu Ser Leu Thr Pro Gly Arg Glu Glu Asn Pro Ser 
1               5                   10                  15      


Ser Val Leu Ala Gln Glu Arg Gly Asp Val Met Asp Phe Tyr Lys Thr 
            20                  25                  30          


Leu Arg Gly Gly Ala Thr Val Lys Val Ser Ala Ser Ser Pro Ser Leu 
        35                  40                  45              


Ala Val Ala Ser Gln Ser Asp Ser Lys Gln Arg Arg Leu Leu Val Asp 
    50                  55                  60                  


Phe Pro Lys Gly Ser Val Ser Asn Ala Gln Gln Pro Asp Leu Ser Lys 
65                  70                  75                  80  


Ala Val Ser Leu Ser Met Gly Leu Tyr Met Gly Glu Thr Glu Thr Lys 
                85                  90                  95      


Val Met Gly Asn Asp Leu Gly Phe Pro Gln Gln Gly Gln Ile Ser Leu 
            100                 105                 110         


Ser Ser Gly Glu Thr Asp Leu Lys Leu Leu Glu Glu Ser Ile Ala Asn 
        115                 120                 125             


Leu Asn Arg Ser Thr Ser Val Pro Glu Asn Pro Lys Ser Ser Ala Ser 
    130                 135                 140                 


Thr Ala Val Ser Ala Ala Pro Thr Glu Lys Glu Phe Pro Lys Thr His 
145                 150                 155                 160 


Ser Asp Val Ser Ser Glu Gln Gln His Leu Lys Gly Gln Thr Gly Thr 
                165                 170                 175     


Asn Gly Gly Asn Val Lys Leu Tyr Thr Thr Asp Gln Ser Thr Phe Asp 
            180                 185                 190         


Ile Leu Gln Asp Leu Glu Phe Ser Ser Gly Ser Pro Gly Lys Glu Thr 
        195                 200                 205             


Asn Glu Ser Pro Trp Arg Ser Asp Leu Leu Ile Asp Glu Asn Cys Leu 
    210                 215                 220                 


Leu Ser Pro Leu Ala Gly Glu Asp Asp Ser Phe Leu Leu Glu Gly Asn 
225                 230                 235                 240 


Ser Asn Glu Asp Cys Lys Pro Leu Ile Leu Pro Asp Thr Lys Pro Lys 
                245                 250                 255     


Ile Lys Asp Asn Gly Asp Leu Val Leu Ser Ser Pro Ser Asn Val Thr 
            260                 265                 270         


Leu Pro Gln Val Lys Thr Glu Lys Glu Asp Phe Ile Glu Leu Cys Thr 
        275                 280                 285             


Pro Gly Val Ile Lys Gln Glu Lys Leu Gly Thr Val Tyr Cys Gln Ala 
    290                 295                 300                 


Ser Phe Pro Gly Ala Asn Ile Ile Gly Asn Lys Met Ser Ala Ile Ser 
305                 310                 315                 320 


Val His Gly Val Ser Thr Ser Gly Gly Gln Met Tyr His Tyr Asp Met 
                325                 330                 335     


Asn Thr Ala Ser Leu Ser Gln Gln Gln Asp Gln Lys Pro Ile Phe Asn 
            340                 345                 350         


Val Ile Pro Pro Ile Pro Val Gly Ser Glu Asn Trp Asn Arg Cys Gln 
        355                 360                 365             


Gly Ser Gly Asp Asp Asn Leu Thr Ser Leu Gly Thr Leu Asn Phe Pro 
    370                 375                 380                 


Gly Arg Thr Val Phe Ser Asn Gly Tyr Ser Ser Pro Ser Met Arg Pro 
385                 390                 395                 400 


Asp Val Ser Ser Pro Pro Ser Ser Ser Ser Thr Ala Thr Thr Gly Pro 
                405                 410                 415     


Pro Pro Lys Leu Cys Leu Val Cys Ser Asp Glu Ala Ser Gly Cys His 
            420                 425                 430         


Tyr Gly Val Leu Thr Cys Gly Ser Cys Lys Val Phe Phe Lys Arg Ala 
        435                 440                 445             


Val Glu Gly Gln His Asn Tyr Leu Cys Ala Gly Arg Asn Asp Cys Ile 
    450                 455                 460                 


Ile Asp Lys Ile Arg Arg Lys Asn Cys Pro Ala Cys Arg Tyr Arg Lys 
465                 470                 475                 480 


Cys Leu Gln Ala Gly Met Asn Leu Glu Ala Arg Lys Thr Lys Lys Lys 
                485                 490                 495     


Ile Lys Gly Ile Gln Gln Ala Thr Thr Gly Val Ser Gln Glu Thr Ser 
            500                 505                 510         


Glu Asn Pro Gly Asn Lys Thr Ile Val Pro Ala Thr Leu Pro Gln Leu 
        515                 520                 525             


Thr Pro Thr Leu Val Ser Leu Leu Glu Val Ile Glu Pro Glu Val Leu 
    530                 535                 540                 


Tyr Ala Gly Tyr Asp Ser Ser Val Pro Asp Ser Thr Trp Arg Ile Met 
545                 550                 555                 560 


Thr Thr Leu Asn Met Leu Gly Gly Arg Gln Val Ile Ala Ala Val Lys 
                565                 570                 575     


Trp Ala Lys Ala Ile Pro Gly Phe Arg Asn Leu His Leu Asp Asp Gln 
            580                 585                 590         


Met Thr Leu Leu Gln Tyr Ser Trp Met Phe Leu Met Ala Phe Ala Leu 
        595                 600                 605             


Gly Trp Arg Ser Tyr Arg Gln Ser Ser Ala Asn Leu Leu Cys Phe Ala 
    610                 615                 620                 


Pro Asp Leu Ile Ile Asn Glu Gln Arg Met Thr Leu Pro Cys Met Tyr 
625                 630                 635                 640 


Asp Gln Cys Lys His Met Leu Tyr Val Ser Ser Glu Leu His Arg Leu 
                645                 650                 655     


Gln Val Ser Tyr Glu Glu Tyr Leu Cys Met Lys Thr Leu Leu Leu Leu 
            660                 665                 670         


Ser Ser Val Pro Lys Asp Gly Leu Lys Ser Gln Glu Leu Phe Asp Glu 
        675                 680                 685             


Ile Arg Met Thr Tyr Ile Lys Glu Leu Gly Lys Ala Ile Val Lys Arg 
    690                 695                 700                 


Glu Gly Asn Ser Ser Gln Asn Trp Gln Arg Phe Tyr Gln Leu Thr Lys 
705                 710                 715                 720 


Leu Leu Asp Ser Met His Glu Val Val Glu Asn Leu Leu Asn Tyr Cys 
                725                 730                 735     


Phe Gln Thr Phe Leu Asp Lys Thr Met Ser Ile Glu Phe Pro Glu Met 
            740                 745                 750         


Leu Ala Glu Ile Ile Thr Asn Gln Ile Pro Lys Tyr Ser Asn Gly Asn 
        755                 760                 765             


Ile Lys Lys Leu Leu Phe His Gln Lys 
    770                 775         


<210>  3467
<211>  683
<212>  PRT
<213>  homo sapiens

<400>  3467

Met Ser Thr Pro Ala Val Pro Gln Asp Leu Gln Leu Pro Pro Ser Gln 
1               5                   10                  15      


Arg Ala Gln Ser Ala Phe Lys Glu Gln Arg Arg Gln Lys Leu Lys Glu 
            20                  25                  30          


His Leu Leu Arg Arg Lys Thr Leu Phe Ala Tyr Lys Gln Glu Asn Glu 
        35                  40                  45              


Met Leu Ser Ser Ser Arg Asp Gln Arg Val Val Thr Ser Glu Asp Gln 
    50                  55                  60                  


Val Gln Glu Gly Thr Lys Val Leu Lys Leu Lys Thr Lys Met Ala Asp 
65                  70                  75                  80  


Lys Glu Asn Met Lys Arg Pro Ala Glu Ser Lys Asn Asn Thr Val Val 
                85                  90                  95      


Gly Lys His Cys Ile Pro Leu Lys Pro Ser Asn Glu Leu Thr Asn Ser 
            100                 105                 110         


Thr Val Val Ile Asp Thr His Lys Pro Lys Asp Ser Asn Gln Thr Pro 
        115                 120                 125             


His Leu Leu Leu Thr Glu Asp Asp Pro Gln Ser Gln His Met Thr Leu 
    130                 135                 140                 


Ser Gln Ala Phe His Leu Lys Asn Asn Ser Lys Lys Lys Gln Met Thr 
145                 150                 155                 160 


Thr Glu Lys Gln Lys Gln Asp Ala Asn Met Pro Lys Lys Pro Val Leu 
                165                 170                 175     


Gly Ser Tyr Arg Gly Gln Ile Val Gln Ser Lys Ile Asn Ser Phe Arg 
            180                 185                 190         


Lys Pro Leu Gln Val Lys Asp Glu Ser Ser Ala Ala Thr Lys Lys Leu 
        195                 200                 205             


Ser Ala Thr Ile Pro Lys Ala Thr Lys Pro Gln Pro Val Asn Thr Ser 
    210                 215                 220                 


Ser Val Thr Val Lys Ser Asn Arg Ser Ser Asn Met Thr Ala Thr Thr 
225                 230                 235                 240 


Lys Phe Val Ser Thr Thr Ser Gln Asn Thr Gln Leu Val Arg Pro Pro 
                245                 250                 255     


Ile Arg Ser His His Ser Asn Thr Arg Asp Thr Val Lys Gln Gly Ile 
            260                 265                 270         


Ser Arg Thr Ser Ala Asn Val Thr Ile Arg Lys Gly Pro His Glu Lys 
        275                 280                 285             


Glu Leu Leu Gln Ser Lys Thr Ala Leu Ser Ser Val Lys Thr Ser Ser 
    290                 295                 300                 


Ser Gln Gly Ile Ile Arg Asn Lys Thr Leu Ser Arg Ser Ile Ala Ser 
305                 310                 315                 320 


Glu Val Ile Ala Arg Pro Ala Ser Leu Ser Asn Asp Lys Leu Met Glu 
                325                 330                 335     


Lys Ser Glu Pro Val Asp Gln Arg Arg His Thr Ala Gly Lys Ala Ile 
            340                 345                 350         


Val Asp Ser Arg Ser Ala Gln Pro Lys Glu Thr Ser Glu Glu Arg Lys 
        355                 360                 365             


Ala Arg Leu Ser Glu Trp Lys Ala Gly Lys Gly Arg Val Leu Lys Arg 
    370                 375                 380                 


Pro Pro Asn Ser Val Val Thr Gln His Glu Pro Ala Gly Gln Asn Glu 
385                 390                 395                 400 


Lys Pro Val Gly Ser Phe Trp Thr Thr Met Ala Glu Glu Asp Glu Gln 
                405                 410                 415     


Arg Leu Phe Thr Glu Lys Val Asn Asn Thr Phe Ser Glu Cys Leu Asn 
            420                 425                 430         


Leu Ile Asn Glu Gly Cys Pro Lys Glu Asp Ile Leu Val Thr Leu Asn 
        435                 440                 445             


Asp Leu Ile Lys Asn Ile Pro Asp Ala Lys Lys Leu Val Lys Tyr Trp 
    450                 455                 460                 


Ile Cys Leu Ala Leu Ile Glu Pro Ile Thr Ser Pro Ile Glu Asn Ile 
465                 470                 475                 480 


Ile Ala Ile Tyr Glu Lys Ala Ile Leu Ala Gly Ala Gln Pro Ile Glu 
                485                 490                 495     


Glu Met Arg His Thr Ile Val Asp Ile Leu Thr Met Lys Ser Gln Glu 
            500                 505                 510         


Lys Ala Asn Leu Gly Glu Asn Met Glu Lys Ser Cys Ala Ser Lys Glu 
        515                 520                 525             


Glu Val Lys Glu Val Ser Ile Glu Asp Thr Gly Val Asp Val Asp Pro 
    530                 535                 540                 


Glu Lys Leu Glu Met Glu Ser Lys Leu His Arg Asn Leu Leu Phe Gln 
545                 550                 555                 560 


Asp Cys Glu Lys Glu Gln Asp Asn Lys Thr Lys Asp Pro Thr His Asp 
                565                 570                 575     


Val Lys Thr Pro Asn Thr Glu Thr Arg Thr Ser Cys Leu Ile Lys Tyr 
            580                 585                 590         


Asn Val Ser Thr Thr Pro Tyr Leu Gln Ser Val Lys Lys Lys Val Gln 
        595                 600                 605             


Phe Asp Gly Thr Asn Ser Ala Phe Lys Glu Leu Lys Phe Leu Thr Pro 
    610                 615                 620                 


Val Arg Arg Ser Arg Arg Leu Gln Glu Lys Thr Ser Lys Leu Pro Asp 
625                 630                 635                 640 


Met Leu Lys Asp His Tyr Pro Cys Val Ser Ser Leu Glu Gln Leu Thr 
                645                 650                 655     


Glu Leu Gly Arg Glu Thr Asp Ala Phe Val Cys Arg Pro Asn Ala Ala 
            660                 665                 670         


Leu Cys Arg Val Tyr Tyr Glu Ala Asp Thr Thr 
        675                 680             


<210>  3468
<211>  393
<212>  PRT
<213>  homo sapiens

<400>  3468

Met Glu Glu Pro Gln Ser Asp Pro Ser Val Glu Pro Pro Leu Ser Gln 
1               5                   10                  15      


Glu Thr Phe Ser Asp Leu Trp Lys Leu Leu Pro Glu Asn Asn Val Leu 
            20                  25                  30          


Ser Pro Leu Pro Ser Gln Ala Met Asp Asp Leu Met Leu Ser Pro Asp 
        35                  40                  45              


Asp Ile Glu Gln Trp Phe Thr Glu Asp Pro Gly Pro Asp Glu Ala Pro 
    50                  55                  60                  


Arg Met Pro Glu Ala Ala Pro Pro Val Ala Pro Ala Pro Ala Ala Pro 
65                  70                  75                  80  


Thr Pro Ala Ala Pro Ala Pro Ala Pro Ser Trp Pro Leu Ser Ser Ser 
                85                  90                  95      


Val Pro Ser Gln Lys Thr Tyr Gln Gly Ser Tyr Gly Phe Arg Leu Gly 
            100                 105                 110         


Phe Leu His Ser Gly Thr Ala Lys Ser Val Thr Cys Thr Tyr Ser Pro 
        115                 120                 125             


Ala Leu Asn Lys Met Phe Cys Gln Leu Ala Lys Thr Cys Pro Val Gln 
    130                 135                 140                 


Leu Trp Val Asp Ser Thr Pro Pro Pro Gly Thr Arg Val Arg Ala Met 
145                 150                 155                 160 


Ala Ile Tyr Lys Gln Ser Gln His Met Thr Glu Val Val Arg Arg Cys 
                165                 170                 175     


Pro His His Glu Arg Cys Ser Asp Ser Asp Gly Leu Ala Pro Pro Gln 
            180                 185                 190         


His Leu Ile Arg Val Glu Gly Asn Leu Arg Val Glu Tyr Leu Asp Asp 
        195                 200                 205             


Arg Asn Thr Phe Arg His Ser Val Val Val Pro Tyr Glu Pro Pro Glu 
    210                 215                 220                 


Val Gly Ser Asp Cys Thr Thr Ile His Tyr Asn Tyr Met Cys Asn Ser 
225                 230                 235                 240 


Ser Cys Met Gly Gly Met Asn Arg Arg Pro Ile Leu Thr Ile Ile Thr 
                245                 250                 255     


Leu Glu Asp Ser Ser Gly Asn Leu Leu Gly Arg Asn Ser Phe Glu Val 
            260                 265                 270         


Arg Val Cys Ala Cys Pro Gly Arg Asp Arg Arg Thr Glu Glu Glu Asn 
        275                 280                 285             


Leu Arg Lys Lys Gly Glu Pro His His Glu Leu Pro Pro Gly Ser Thr 
    290                 295                 300                 


Lys Arg Ala Leu Pro Asn Asn Thr Ser Ser Ser Pro Gln Pro Lys Lys 
305                 310                 315                 320 


Lys Pro Leu Asp Gly Glu Tyr Phe Thr Leu Gln Ile Arg Gly Arg Glu 
                325                 330                 335     


Arg Phe Glu Met Phe Arg Glu Leu Asn Glu Ala Leu Glu Leu Lys Asp 
            340                 345                 350         


Ala Gln Ala Gly Lys Glu Pro Gly Gly Ser Arg Ala His Ser Ser His 
        355                 360                 365             


Leu Lys Ser Lys Lys Gly Gln Ser Thr Ser Arg His Lys Lys Leu Met 
    370                 375                 380                 


Phe Lys Thr Glu Gly Pro Asp Ser Asp 
385                 390             


<210>  3469
<211>  393
<212>  PRT
<213>  homo sapiens

<400>  3469

Met Glu Glu Pro Gln Ser Asp Pro Ser Val Glu Pro Pro Leu Ser Gln 
1               5                   10                  15      


Glu Thr Phe Ser Asp Leu Trp Lys Leu Leu Pro Glu Asn Asn Val Leu 
            20                  25                  30          


Ser Pro Leu Pro Ser Gln Ala Met Asp Asp Leu Met Leu Ser Pro Asp 
        35                  40                  45              


Asp Ile Glu Gln Trp Phe Thr Glu Asp Pro Gly Pro Asp Glu Ala Pro 
    50                  55                  60                  


Arg Met Pro Glu Ala Ala Pro Pro Val Ala Pro Ala Pro Ala Ala Pro 
65                  70                  75                  80  


Thr Pro Ala Ala Pro Ala Pro Ala Pro Ser Trp Pro Leu Ser Ser Ser 
                85                  90                  95      


Val Pro Ser Gln Lys Thr Tyr Gln Gly Ser Tyr Gly Phe Arg Leu Gly 
            100                 105                 110         


Phe Leu His Ser Gly Thr Ala Lys Ser Val Thr Cys Thr Tyr Ser Pro 
        115                 120                 125             


Ala Leu Asn Lys Met Phe Cys Gln Leu Ala Lys Thr Cys Pro Val Gln 
    130                 135                 140                 


Leu Trp Val Asp Ser Thr Pro Pro Pro Gly Thr Arg Val Arg Ala Met 
145                 150                 155                 160 


Ala Ile Tyr Lys Gln Ser Gln His Met Thr Glu Val Val Arg Arg Cys 
                165                 170                 175     


Pro His His Glu Arg Cys Ser Asp Ser Asp Gly Leu Ala Pro Pro Gln 
            180                 185                 190         


His Leu Ile Arg Val Glu Gly Asn Leu Arg Val Glu Tyr Leu Asp Asp 
        195                 200                 205             


Arg Asn Thr Phe Arg His Ser Val Val Val Pro Tyr Glu Pro Pro Glu 
    210                 215                 220                 


Val Gly Ser Asp Cys Thr Thr Ile His Tyr Asn Tyr Met Cys Asn Ser 
225                 230                 235                 240 


Ser Cys Met Gly Gly Met Asn Arg Arg Pro Ile Leu Thr Ile Ile Thr 
                245                 250                 255     


Leu Glu Asp Ser Ser Gly Asn Leu Leu Gly Arg Asn Ser Phe Glu Val 
            260                 265                 270         


Arg Val Cys Ala Cys Pro Gly Arg Asp Arg Arg Thr Glu Glu Glu Asn 
        275                 280                 285             


Leu Arg Lys Lys Gly Glu Pro His His Glu Leu Pro Pro Gly Ser Thr 
    290                 295                 300                 


Lys Arg Ala Leu Pro Asn Asn Thr Ser Ser Ser Pro Gln Pro Lys Lys 
305                 310                 315                 320 


Lys Pro Leu Asp Gly Glu Tyr Phe Thr Leu Gln Ile Arg Gly Arg Glu 
                325                 330                 335     


Arg Phe Glu Met Phe Arg Glu Leu Asn Glu Ala Leu Glu Leu Lys Asp 
            340                 345                 350         


Ala Gln Ala Gly Lys Glu Pro Gly Gly Ser Arg Ala His Ser Ser His 
        355                 360                 365             


Leu Lys Ser Lys Lys Gly Gln Ser Thr Ser Arg His Lys Lys Leu Met 
    370                 375                 380                 


Phe Lys Thr Glu Gly Pro Asp Ser Asp 
385                 390             


<210>  3470
<211>  346
<212>  PRT
<213>  homo sapiens

<400>  3470

Met Glu Glu Pro Gln Ser Asp Pro Ser Val Glu Pro Pro Leu Ser Gln 
1               5                   10                  15      


Glu Thr Phe Ser Asp Leu Trp Lys Leu Leu Pro Glu Asn Asn Val Leu 
            20                  25                  30          


Ser Pro Leu Pro Ser Gln Ala Met Asp Asp Leu Met Leu Ser Pro Asp 
        35                  40                  45              


Asp Ile Glu Gln Trp Phe Thr Glu Asp Pro Gly Pro Asp Glu Ala Pro 
    50                  55                  60                  


Arg Met Pro Glu Ala Ala Pro Pro Val Ala Pro Ala Pro Ala Ala Pro 
65                  70                  75                  80  


Thr Pro Ala Ala Pro Ala Pro Ala Pro Ser Trp Pro Leu Ser Ser Ser 
                85                  90                  95      


Val Pro Ser Gln Lys Thr Tyr Gln Gly Ser Tyr Gly Phe Arg Leu Gly 
            100                 105                 110         


Phe Leu His Ser Gly Thr Ala Lys Ser Val Thr Cys Thr Tyr Ser Pro 
        115                 120                 125             


Ala Leu Asn Lys Met Phe Cys Gln Leu Ala Lys Thr Cys Pro Val Gln 
    130                 135                 140                 


Leu Trp Val Asp Ser Thr Pro Pro Pro Gly Thr Arg Val Arg Ala Met 
145                 150                 155                 160 


Ala Ile Tyr Lys Gln Ser Gln His Met Thr Glu Val Val Arg Arg Cys 
                165                 170                 175     


Pro His His Glu Arg Cys Ser Asp Ser Asp Gly Leu Ala Pro Pro Gln 
            180                 185                 190         


His Leu Ile Arg Val Glu Gly Asn Leu Arg Val Glu Tyr Leu Asp Asp 
        195                 200                 205             


Arg Asn Thr Phe Arg His Ser Val Val Val Pro Tyr Glu Pro Pro Glu 
    210                 215                 220                 


Val Gly Ser Asp Cys Thr Thr Ile His Tyr Asn Tyr Met Cys Asn Ser 
225                 230                 235                 240 


Ser Cys Met Gly Gly Met Asn Arg Arg Pro Ile Leu Thr Ile Ile Thr 
                245                 250                 255     


Leu Glu Asp Ser Ser Gly Asn Leu Leu Gly Arg Asn Ser Phe Glu Val 
            260                 265                 270         


Arg Val Cys Ala Cys Pro Gly Arg Asp Arg Arg Thr Glu Glu Glu Asn 
        275                 280                 285             


Leu Arg Lys Lys Gly Glu Pro His His Glu Leu Pro Pro Gly Ser Thr 
    290                 295                 300                 


Lys Arg Ala Leu Pro Asn Asn Thr Ser Ser Ser Pro Gln Pro Lys Lys 
305                 310                 315                 320 


Lys Pro Leu Asp Gly Glu Tyr Phe Thr Leu Gln Met Leu Leu Asp Leu 
                325                 330                 335     


Arg Trp Cys Tyr Phe Leu Ile Asn Ser Ser 
            340                 345     


<210>  3471
<211>  592
<212>  PRT
<213>  homo sapiens

<400>  3471

Met Ala Pro Pro Val Ala Glu Arg Gly Leu Lys Ser Val Val Trp Gln 
1               5                   10                  15      


Lys Ile Lys Ala Thr Val Phe Asp Asp Cys Lys Lys Glu Gly Glu Trp 
            20                  25                  30          


Lys Ile Met Leu Leu Asp Glu Phe Thr Thr Lys Leu Leu Ala Ser Cys 
        35                  40                  45              


Cys Lys Met Thr Asp Leu Leu Glu Glu Gly Ile Thr Val Val Glu Asn 
    50                  55                  60                  


Ile Tyr Lys Asn Arg Glu Pro Val Arg Gln Met Lys Ala Leu Tyr Phe 
65                  70                  75                  80  


Ile Thr Pro Thr Ser Lys Ser Val Asp Cys Phe Leu His Asp Phe Ala 
                85                  90                  95      


Ser Lys Ser Glu Asn Lys Tyr Lys Ala Ala Tyr Ile Tyr Phe Thr Asp 
            100                 105                 110         


Phe Cys Pro Asp Asn Leu Phe Asn Lys Ile Lys Ala Ser Cys Ser Lys 
        115                 120                 125             


Ser Ile Arg Arg Cys Lys Glu Ile Asn Ile Ser Phe Ile Pro His Glu 
    130                 135                 140                 


Ser Gln Val Tyr Thr Leu Asp Val Pro Asp Ala Phe Tyr Tyr Cys Tyr 
145                 150                 155                 160 


Ser Pro Asp Pro Gly Asn Ala Lys Gly Lys Asp Ala Ile Met Glu Thr 
                165                 170                 175     


Met Ala Asp Gln Ile Val Thr Val Cys Ala Thr Leu Asp Glu Asn Pro 
            180                 185                 190         


Gly Val Arg Tyr Lys Ser Lys Pro Leu Asp Asn Ala Ser Lys Leu Ala 
        195                 200                 205             


Gln Leu Val Glu Lys Lys Leu Glu Asp Tyr Tyr Lys Ile Asp Glu Lys 
    210                 215                 220                 


Ser Leu Ile Lys Gly Lys Thr His Ser Gln Leu Leu Ile Ile Asp Arg 
225                 230                 235                 240 


Gly Phe Asp Pro Val Ser Thr Val Leu His Glu Leu Thr Phe Gln Ala 
                245                 250                 255     


Met Ala Tyr Asp Leu Leu Pro Ile Glu Asn Asp Thr Tyr Lys Tyr Lys 
            260                 265                 270         


Thr Asp Gly Lys Glu Lys Glu Ala Ile Leu Glu Glu Glu Asp Asp Leu 
        275                 280                 285             


Trp Val Arg Ile Arg His Arg His Ile Ala Val Val Leu Glu Glu Ile 
    290                 295                 300                 


Pro Lys Leu Met Lys Glu Ile Ser Ser Thr Lys Lys Ala Thr Glu Gly 
305                 310                 315                 320 


Lys Thr Ser Leu Ser Ala Leu Thr Gln Leu Met Lys Lys Met Pro His 
                325                 330                 335     


Phe Arg Lys Gln Ile Thr Lys Gln Val Val His Leu Asn Leu Ala Glu 
            340                 345                 350         


Asp Cys Met Asn Lys Phe Lys Leu Asn Ile Glu Lys Leu Cys Lys Thr 
        355                 360                 365             


Glu Gln Asp Leu Ala Leu Gly Thr Asp Ala Glu Gly Gln Lys Val Lys 
    370                 375                 380                 


Asp Ser Met Arg Val Leu Leu Pro Val Leu Leu Asn Lys Asn His Asp 
385                 390                 395                 400 


Asn Cys Asp Lys Ile Arg Ala Ile Leu Leu Tyr Ile Phe Ser Ile Asn 
                405                 410                 415     


Gly Thr Thr Glu Glu Asn Leu Asp Arg Leu Ile Gln Asn Val Lys Ile 
            420                 425                 430         


Glu Asn Glu Ser Asp Met Ile Arg Asn Trp Ser Tyr Leu Gly Val Pro 
        435                 440                 445             


Ile Val Pro Gln Ser Gln Gln Gly Lys Pro Leu Arg Lys Asp Arg Ser 
    450                 455                 460                 


Ala Glu Glu Thr Phe Gln Leu Ser Arg Trp Thr Pro Phe Ile Lys Asp 
465                 470                 475                 480 


Ile Met Glu Asp Ala Ile Asp Asn Arg Leu Asp Ser Lys Glu Trp Pro 
                485                 490                 495     


Tyr Cys Ser Gln Cys Pro Ala Val Trp Asn Gly Ser Gly Ala Val Ser 
            500                 505                 510         


Ala Arg Gln Lys Pro Arg Ala Asn Tyr Leu Glu Asp Arg Lys Asn Gly 
        515                 520                 525             


Ser Lys Leu Ile Val Phe Val Ile Gly Gly Ile Thr Tyr Ser Glu Val 
    530                 535                 540                 


Arg Cys Ala Tyr Glu Val Ser Gln Ala His Lys Ser Cys Glu Val Ile 
545                 550                 555                 560 


Ile Gly Ser Thr His Val Leu Thr Pro Lys Lys Leu Leu Asp Asp Ile 
                565                 570                 575     


Lys Met Leu Asn Lys Pro Lys Asp Lys Val Ser Leu Ile Lys Asp Glu 
            580                 585                 590         


<210>  3472
<211>  642
<212>  PRT
<213>  homo sapiens

<400>  3472

Met Ala Thr Ala Met Asp Trp Leu Pro Trp Ser Leu Leu Leu Phe Ser 
1               5                   10                  15      


Leu Met Cys Glu Thr Ser Ala Phe Tyr Val Pro Gly Val Ala Pro Ile 
            20                  25                  30          


Asn Phe His Gln Asn Asp Pro Val Glu Ile Lys Ala Val Lys Leu Thr 
        35                  40                  45              


Ser Ser Arg Thr Gln Leu Pro Tyr Glu Tyr Tyr Ser Leu Pro Phe Cys 
    50                  55                  60                  


Gln Pro Ser Lys Ile Thr Tyr Lys Ala Glu Asn Leu Gly Glu Val Leu 
65                  70                  75                  80  


Arg Gly Asp Arg Ile Val Asn Thr Pro Phe Gln Val Leu Met Asn Ser 
                85                  90                  95      


Glu Lys Lys Cys Glu Val Leu Cys Ser Gln Ser Asn Lys Pro Val Thr 
            100                 105                 110         


Leu Thr Val Glu Gln Ser Arg Leu Val Ala Glu Arg Ile Thr Glu Asp 
        115                 120                 125             


Tyr Tyr Val His Leu Ile Ala Asp Asn Leu Pro Val Ala Thr Arg Leu 
    130                 135                 140                 


Glu Leu Tyr Ser Asn Arg Asp Ser Asp Asp Lys Lys Lys Glu Lys Asp 
145                 150                 155                 160 


Val Gln Phe Glu His Gly Tyr Arg Leu Gly Phe Thr Asp Val Asn Lys 
                165                 170                 175     


Ile Tyr Leu His Asn His Leu Ser Phe Ile Leu Tyr Tyr His Arg Glu 
            180                 185                 190         


Asp Met Glu Glu Asp Gln Glu His Thr Tyr Arg Val Val Arg Phe Glu 
        195                 200                 205             


Val Ile Pro Gln Ser Ile Arg Leu Glu Asp Leu Lys Ala Asp Glu Lys 
    210                 215                 220                 


Ser Ser Cys Thr Leu Pro Glu Gly Thr Asn Ser Ser Pro Gln Glu Ile 
225                 230                 235                 240 


Asp Pro Thr Lys Glu Asn Gln Leu Tyr Phe Thr Tyr Ser Val His Trp 
                245                 250                 255     


Glu Glu Ser Asp Ile Lys Trp Ala Ser Arg Trp Asp Thr Tyr Leu Thr 
            260                 265                 270         


Met Ser Asp Val Gln Ile His Trp Phe Ser Ile Ile Asn Ser Val Val 
        275                 280                 285             


Val Val Phe Phe Leu Ser Gly Ile Leu Ser Met Ile Ile Ile Arg Thr 
    290                 295                 300                 


Leu Arg Lys Asp Ile Ala Asn Tyr Asn Lys Glu Asp Asp Ile Glu Asp 
305                 310                 315                 320 


Thr Met Glu Glu Ser Gly Trp Lys Leu Val His Gly Asp Val Phe Arg 
                325                 330                 335     


Pro Pro Gln Tyr Pro Met Ile Leu Ser Ser Leu Leu Gly Ser Gly Ile 
            340                 345                 350         


Gln Leu Phe Cys Met Ile Leu Ile Val Ile Phe Val Ala Met Leu Gly 
        355                 360                 365             


Met Leu Ser Pro Ser Ser Arg Gly Ala Leu Met Thr Thr Ala Cys Phe 
    370                 375                 380                 


Leu Phe Met Phe Met Gly Val Phe Gly Gly Phe Ser Ala Gly Arg Leu 
385                 390                 395                 400 


Tyr Arg Thr Leu Lys Gly His Arg Trp Lys Lys Gly Ala Phe Cys Thr 
                405                 410                 415     


Ala Thr Leu Tyr Pro Gly Val Val Phe Gly Ile Cys Phe Val Leu Asn 
            420                 425                 430         


Cys Phe Ile Trp Gly Lys His Ser Ser Gly Ala Val Pro Phe Pro Thr 
        435                 440                 445             


Met Val Ala Leu Leu Cys Met Trp Phe Gly Ile Ser Leu Pro Leu Val 
    450                 455                 460                 


Tyr Leu Gly Tyr Tyr Phe Gly Phe Arg Lys Gln Pro Tyr Asp Asn Pro 
465                 470                 475                 480 


Val Arg Thr Asn Gln Ile Pro Arg Gln Ile Pro Glu Gln Arg Trp Tyr 
                485                 490                 495     


Met Asn Arg Phe Val Gly Ile Leu Met Ala Gly Ile Leu Pro Phe Gly 
            500                 505                 510         


Ala Met Phe Ile Glu Leu Phe Phe Ile Phe Ser Ala Ile Trp Glu Asn 
        515                 520                 525             


Gln Phe Tyr Tyr Leu Phe Gly Phe Leu Phe Leu Val Phe Ile Ile Leu 
    530                 535                 540                 


Val Val Ser Cys Ser Gln Ile Ser Ile Val Met Val Tyr Phe Gln Leu 
545                 550                 555                 560 


Cys Ala Glu Asp Tyr Arg Trp Trp Trp Arg Asn Phe Leu Val Ser Gly 
                565                 570                 575     


Gly Ser Ala Phe Tyr Val Leu Val Tyr Ala Ile Phe Tyr Phe Val Asn 
            580                 585                 590         


Lys Leu Asp Ile Val Glu Phe Ile Pro Ser Leu Leu Tyr Phe Gly Tyr 
        595                 600                 605             


Thr Ala Leu Met Val Leu Ser Phe Trp Leu Leu Thr Gly Thr Ile Gly 
    610                 615                 620                 


Phe Tyr Ala Ala Tyr Met Phe Val Arg Lys Ile Tyr Ala Ala Val Lys 
625                 630                 635                 640 


Ile Asp 
        


<210>  3473
<211>  483
<212>  PRT
<213>  homo sapiens

<400>  3473

Met Ser Tyr Pro Gln Gly Tyr Leu Tyr Gln Pro Ser Ala Ser Leu Ala 
1               5                   10                  15      


Leu Tyr Ser Cys Pro Ala Tyr Ser Thr Ser Val Ile Ser Gly Pro Arg 
            20                  25                  30          


Thr Asp Glu Leu Gly Arg Ser Ser Ser Gly Ser Ala Phe Ser Pro Tyr 
        35                  40                  45              


Ala Gly Ser Thr Ala Phe Thr Ala Pro Ser Pro Gly Tyr Asn Ser His 
    50                  55                  60                  


Leu Gln Tyr Gly Ala Asp Pro Ala Ala Ala Ala Ala Ala Ala Phe Ser 
65                  70                  75                  80  


Ser Tyr Val Gly Ser Pro Tyr Asp His Thr Pro Gly Met Ala Gly Ser 
                85                  90                  95      


Leu Gly Tyr His Pro Tyr Ala Ala Pro Leu Gly Ser Tyr Pro Tyr Gly 
            100                 105                 110         


Asp Pro Ala Tyr Arg Lys Asn Ala Thr Arg Asp Ala Thr Ala Thr Leu 
        115                 120                 125             


Lys Ala Trp Leu Asn Glu His Arg Lys Asn Pro Tyr Pro Thr Lys Gly 
    130                 135                 140                 


Glu Lys Ile Met Leu Ala Ile Ile Thr Lys Met Thr Leu Thr Gln Val 
145                 150                 155                 160 


Ser Thr Trp Phe Ala Asn Ala Arg Arg Arg Leu Lys Lys Glu Asn Lys 
                165                 170                 175     


Met Thr Trp Thr Pro Arg Asn Arg Ser Glu Asp Glu Glu Glu Glu Glu 
            180                 185                 190         


Asn Ile Asp Leu Glu Lys Asn Asp Glu Asp Glu Pro Gln Lys Pro Glu 
        195                 200                 205             


Asp Lys Gly Asp Pro Glu Gly Pro Glu Ala Gly Gly Ala Glu Gln Lys 
    210                 215                 220                 


Ala Ala Ser Gly Cys Glu Arg Leu Gln Gly Pro Pro Thr Pro Ala Gly 
225                 230                 235                 240 


Lys Glu Thr Glu Gly Ser Leu Ser Asp Ser Asp Phe Lys Glu Pro Pro 
                245                 250                 255     


Ser Glu Gly Arg Leu Asp Ala Leu Gln Gly Pro Pro Arg Thr Gly Gly 
            260                 265                 270         


Pro Ser Pro Ala Gly Pro Ala Ala Ala Arg Leu Ala Glu Asp Pro Ala 
        275                 280                 285             


Pro His Tyr Pro Ala Gly Ala Pro Ala Pro Gly Pro His Pro Ala Ala 
    290                 295                 300                 


Gly Glu Val Pro Pro Gly Pro Gly Gly Pro Ser Val Ile His Ser Pro 
305                 310                 315                 320 


Pro Pro Pro Pro Pro Pro Ala Val Leu Ala Lys Pro Lys Leu Trp Ser 
                325                 330                 335     


Leu Ala Glu Ile Ala Thr Ser Ser Asp Lys Val Lys Asp Gly Gly Gly 
            340                 345                 350         


Gly Asn Glu Gly Ser Pro Cys Pro Pro Cys Pro Gly Pro Ile Ala Gly 
        355                 360                 365             


Gln Ala Leu Gly Gly Ser Arg Ala Ser Pro Ala Pro Ala Pro Ser Arg 
    370                 375                 380                 


Ser Pro Ser Ala Gln Cys Pro Phe Pro Gly Gly Thr Val Leu Ser Arg 
385                 390                 395                 400 


Pro Leu Tyr Tyr Thr Ala Pro Phe Tyr Pro Gly Tyr Thr Asn Tyr Gly 
                405                 410                 415     


Ser Phe Gly His Leu His Gly His Pro Gly Pro Gly Pro Gly Pro Thr 
            420                 425                 430         


Thr Gly Pro Gly Ser His Phe Asn Gly Leu Asn Gln Thr Val Leu Asn 
        435                 440                 445             


Arg Ala Asp Ala Leu Ala Lys Asp Pro Lys Met Leu Arg Ser Gln Ser 
    450                 455                 460                 


Gln Leu Asp Leu Cys Lys Asp Ser Pro Tyr Glu Leu Lys Lys Gly Met 
465                 470                 475                 480 


Ser Asp Ile 
            


<210>  3474
<211>  381
<212>  PRT
<213>  homo sapiens

<400>  3474

Met Asp Gly Val Gly Val Pro Ala Ser Met Tyr Gly Asp Pro His Ala 
1               5                   10                  15      


Pro Arg Pro Ile Pro Pro Val His His Leu Asn His Gly Pro Pro Leu 
            20                  25                  30          


His Ala Thr Gln His Tyr Gly Ala His Ala Pro His Pro Asn Val Met 
        35                  40                  45              


Pro Ala Ser Met Gly Ser Ala Val Asn Asp Ala Leu Lys Arg Asp Lys 
    50                  55                  60                  


Asp Ala Ile Tyr Gly His Pro Leu Phe Pro Leu Leu Ala Leu Val Phe 
65                  70                  75                  80  


Glu Lys Cys Glu Leu Ala Thr Cys Thr Pro Arg Glu Pro Gly Val Ala 
                85                  90                  95      


Gly Gly Asp Val Cys Ser Ser Asp Ser Phe Asn Glu Asp Ile Ala Val 
            100                 105                 110         


Phe Ala Lys Gln Val Arg Ala Glu Lys Pro Leu Phe Ser Ser Asn Pro 
        115                 120                 125             


Glu Leu Asp Asn Leu Met Ile Gln Ala Ile Gln Val Leu Arg Phe His 
    130                 135                 140                 


Leu Leu Glu Leu Glu Lys Val His Glu Leu Cys Asp Asn Phe Cys His 
145                 150                 155                 160 


Arg Tyr Ile Ser Cys Leu Lys Gly Lys Met Pro Ile Asp Leu Val Ile 
                165                 170                 175     


Asp Glu Arg Asp Gly Ser Ser Lys Ser Asp His Glu Glu Leu Ser Gly 
            180                 185                 190         


Ser Ser Thr Asn Leu Ala Asp His Asn Pro Ser Ser Trp Arg Asp His 
        195                 200                 205             


Asp Asp Ala Thr Ser Thr His Ser Ala Gly Thr Pro Gly Pro Ser Ser 
    210                 215                 220                 


Gly Gly His Ala Ser Gln Ser Gly Asp Asn Ser Ser Glu Gln Gly Asp 
225                 230                 235                 240 


Gly Leu Asp Asn Ser Val Ala Ser Pro Gly Thr Gly Asp Asp Asp Asp 
                245                 250                 255     


Pro Asp Lys Asp Lys Lys Arg Gln Lys Lys Arg Gly Ile Phe Pro Lys 
            260                 265                 270         


Val Ala Thr Asn Ile Met Arg Ala Trp Leu Phe Gln His Leu Thr His 
        275                 280                 285             


Pro Tyr Pro Ser Glu Glu Gln Lys Lys Gln Leu Ala Gln Asp Thr Gly 
    290                 295                 300                 


Leu Thr Ile Leu Gln Val Asn Asn Trp Phe Ile Asn Ala Arg Arg Arg 
305                 310                 315                 320 


Ile Val Gln Pro Met Ile Asp Gln Ser Asn Arg Ala Val Ser Gln Gly 
                325                 330                 335     


Ala Ala Tyr Ser Pro Glu Gly Gln Pro Met Gly Ser Phe Val Leu Asp 
            340                 345                 350         


Gly Gln Gln His Met Gly Ile Arg Pro Ala Gly Pro Met Ser Gly Met 
        355                 360                 365             


Gly Met Asn Met Gly Met Asp Gly Gln Trp His Tyr Met 
    370                 375                 380     


<210>  3475
<211>  477
<212>  PRT
<213>  homo sapiens

<400>  3475

Met Ala Gln Arg Tyr Asp Glu Leu Pro His Tyr Gly Gly Met Asp Gly 
1               5                   10                  15      


Val Gly Val Pro Ala Ser Met Tyr Gly Asp Pro His Ala Pro Arg Pro 
            20                  25                  30          


Ile Pro Pro Val His His Leu Asn His Gly Pro Pro Leu His Ala Thr 
        35                  40                  45              


Gln His Tyr Gly Ala His Ala Pro His Pro Asn Val Met Pro Ala Ser 
    50                  55                  60                  


Met Gly Ser Ala Val Asn Asp Ala Leu Lys Arg Asp Lys Asp Ala Ile 
65                  70                  75                  80  


Tyr Gly His Pro Leu Phe Pro Leu Leu Ala Leu Val Phe Glu Lys Cys 
                85                  90                  95      


Glu Leu Ala Thr Cys Thr Pro Arg Glu Pro Gly Val Ala Gly Gly Asp 
            100                 105                 110         


Val Cys Ser Ser Asp Ser Phe Asn Glu Asp Ile Ala Val Phe Ala Lys 
        115                 120                 125             


Gln Val Arg Ala Glu Lys Pro Leu Phe Ser Ser Asn Pro Glu Leu Asp 
    130                 135                 140                 


Asn Leu Met Ile Gln Ala Ile Gln Val Leu Arg Phe His Leu Leu Glu 
145                 150                 155                 160 


Leu Glu Lys Val His Glu Leu Cys Asp Asn Phe Cys His Arg Tyr Ile 
                165                 170                 175     


Ser Cys Leu Lys Gly Lys Met Pro Ile Asp Leu Val Ile Asp Glu Arg 
            180                 185                 190         


Asp Gly Ser Ser Lys Ser Asp His Glu Glu Leu Ser Gly Ser Ser Thr 
        195                 200                 205             


Asn Leu Ala Asp His Asn Pro Ser Ser Trp Arg Asp His Asp Asp Ala 
    210                 215                 220                 


Thr Ser Thr His Ser Ala Gly Thr Pro Gly Pro Ser Ser Gly Gly His 
225                 230                 235                 240 


Ala Ser Gln Ser Gly Asp Asn Ser Ser Glu Gln Gly Asp Gly Leu Asp 
                245                 250                 255     


Asn Ser Val Ala Ser Pro Gly Thr Gly Asp Asp Asp Asp Pro Asp Lys 
            260                 265                 270         


Asp Lys Lys Arg Gln Lys Lys Arg Gly Ile Phe Pro Lys Val Ala Thr 
        275                 280                 285             


Asn Ile Met Arg Ala Trp Leu Phe Gln His Leu Thr His Pro Tyr Pro 
    290                 295                 300                 


Ser Glu Glu Gln Lys Lys Gln Leu Ala Gln Asp Thr Gly Leu Thr Ile 
305                 310                 315                 320 


Leu Gln Val Asn Asn Trp Phe Ile Asn Ala Arg Arg Arg Ile Val Gln 
                325                 330                 335     


Pro Met Ile Asp Gln Ser Asn Arg Ala Gly Phe Leu Leu Asp Pro Ser 
            340                 345                 350         


Val Ser Gln Gly Ala Ala Tyr Ser Pro Glu Gly Gln Pro Met Gly Ser 
        355                 360                 365             


Phe Val Leu Asp Gly Gln Gln His Met Gly Ile Arg Pro Ala Gly Leu 
    370                 375                 380                 


Gln Ser Met Pro Gly Asp Tyr Val Ser Gln Gly Gly Pro Met Gly Met 
385                 390                 395                 400 


Ser Met Ala Gln Pro Ser Tyr Thr Pro Pro Gln Met Thr Pro His Pro 
                405                 410                 415     


Thr Gln Leu Arg His Gly Pro Pro Met His Ser Tyr Leu Pro Ser His 
            420                 425                 430         


Pro His His Pro Ala Met Met Met His Gly Gly Pro Pro Thr His Pro 
        435                 440                 445             


Gly Met Thr Met Ser Ala Gln Ser Pro Thr Met Leu Asn Ser Val Asp 
    450                 455                 460                 


Pro Asn Val Gly Gly Gln Val Met Asp Ile His Ala Gln 
465                 470                 475         


<210>  3476
<211>  778
<212>  PRT
<213>  homo sapiens

<400>  3476

Met Asp Glu Met Thr Ala Val Val Lys Ile Glu Lys Gly Val Gly Gly 
1               5                   10                  15      


Asn Asn Gly Gly Asn Gly Asn Gly Gly Gly Ala Phe Ser Gln Ala Arg 
            20                  25                  30          


Ser Ser Ser Thr Gly Ser Ser Ser Ser Thr Gly Gly Gly Gly Gln Glu 
        35                  40                  45              


Ser Gln Pro Ser Pro Leu Ala Leu Leu Ala Ala Thr Cys Ser Arg Ile 
    50                  55                  60                  


Glu Ser Pro Asn Glu Asn Ser Asn Asn Ser Gln Gly Pro Ser Gln Ser 
65                  70                  75                  80  


Gly Gly Thr Gly Glu Leu Asp Leu Thr Ala Thr Gln Leu Ser Gln Gly 
                85                  90                  95      


Ala Asn Gly Trp Gln Ile Ile Ser Ser Ser Ser Gly Ala Thr Pro Thr 
            100                 105                 110         


Ser Lys Glu Gln Ser Gly Ser Ser Thr Asn Gly Ser Asn Gly Ser Glu 
        115                 120                 125             


Ser Ser Lys Asn Arg Thr Val Ser Gly Gly Gln Tyr Val Val Ala Ala 
    130                 135                 140                 


Ala Pro Asn Leu Gln Asn Gln Gln Val Leu Thr Gly Leu Pro Gly Val 
145                 150                 155                 160 


Met Pro Asn Ile Gln Tyr Gln Val Ile Pro Gln Phe Gln Thr Val Asp 
                165                 170                 175     


Gly Gln Gln Leu Gln Phe Ala Ala Thr Gly Ala Gln Val Gln Gln Asp 
            180                 185                 190         


Gly Ser Gly Gln Ile Gln Ile Ile Pro Gly Ala Asn Gln Gln Ile Ile 
        195                 200                 205             


Thr Asn Arg Gly Ser Gly Gly Asn Ile Ile Ala Ala Met Pro Asn Leu 
    210                 215                 220                 


Leu Gln Gln Ala Val Pro Leu Gln Gly Leu Ala Asn Asn Val Leu Ser 
225                 230                 235                 240 


Gly Gln Thr Gln Tyr Val Thr Asn Val Pro Val Ala Leu Asn Gly Asn 
                245                 250                 255     


Ile Thr Leu Leu Pro Val Asn Ser Val Ser Ala Ala Thr Leu Thr Pro 
            260                 265                 270         


Ser Ser Gln Ala Val Thr Ile Ser Ser Ser Gly Ser Gln Glu Ser Gly 
        275                 280                 285             


Ser Gln Pro Val Thr Ser Gly Thr Thr Ile Ser Ser Ala Ser Leu Val 
    290                 295                 300                 


Ser Ser Gln Ala Ser Ser Ser Ser Phe Phe Thr Asn Ala Asn Ser Tyr 
305                 310                 315                 320 


Ser Thr Thr Thr Thr Thr Ser Asn Met Gly Ile Met Asn Phe Thr Thr 
                325                 330                 335     


Ser Gly Ser Ser Gly Thr Asn Ser Gln Gly Gln Thr Pro Gln Arg Val 
            340                 345                 350         


Ser Gly Leu Gln Gly Ser Asp Ala Leu Asn Ile Gln Gln Asn Gln Thr 
        355                 360                 365             


Ser Gly Gly Ser Leu Gln Ala Gly Gln Gln Lys Glu Gly Glu Gln Asn 
    370                 375                 380                 


Gln Gln Thr Gln Gln Gln Gln Ile Leu Ile Gln Pro Gln Leu Val Gln 
385                 390                 395                 400 


Gly Gly Gln Ala Leu Gln Ala Leu Gln Ala Ala Pro Leu Ser Gly Gln 
                405                 410                 415     


Thr Phe Thr Thr Gln Ala Ile Ser Gln Glu Thr Leu Gln Asn Leu Gln 
            420                 425                 430         


Leu Gln Ala Val Pro Asn Ser Gly Pro Ile Ile Ile Arg Thr Pro Thr 
        435                 440                 445             


Val Gly Pro Asn Gly Gln Val Ser Trp Gln Thr Leu Gln Leu Gln Asn 
    450                 455                 460                 


Leu Gln Val Gln Asn Pro Gln Ala Gln Thr Ile Thr Leu Ala Pro Met 
465                 470                 475                 480 


Gln Gly Val Ser Leu Gly Gln Thr Ser Ser Ser Asn Thr Thr Leu Thr 
                485                 490                 495     


Pro Ile Ala Ser Ala Ala Ser Ile Pro Ala Gly Thr Val Thr Val Asn 
            500                 505                 510         


Ala Ala Gln Leu Ser Ser Met Pro Gly Leu Gln Thr Ile Asn Leu Ser 
        515                 520                 525             


Ala Leu Gly Thr Ser Gly Ile Gln Val His Pro Ile Gln Gly Leu Pro 
    530                 535                 540                 


Leu Ala Ile Ala Asn Ala Pro Gly Asp His Gly Ala Gln Leu Gly Leu 
545                 550                 555                 560 


His Gly Ala Gly Gly Asp Gly Ile His Asp Asp Thr Ala Gly Gly Glu 
                565                 570                 575     


Glu Gly Glu Asn Ser Pro Asp Ala Gln Pro Gln Ala Gly Arg Arg Thr 
            580                 585                 590         


Arg Arg Glu Ala Cys Thr Cys Pro Tyr Cys Lys Asp Ser Glu Gly Arg 
        595                 600                 605             


Gly Ser Gly Asp Pro Gly Lys Lys Lys Gln His Ile Cys His Ile Gln 
    610                 615                 620                 


Gly Cys Gly Lys Val Tyr Gly Lys Thr Ser His Leu Arg Ala His Leu 
625                 630                 635                 640 


Arg Trp His Thr Gly Glu Arg Pro Phe Met Cys Thr Trp Ser Tyr Cys 
                645                 650                 655     


Gly Lys Arg Phe Thr Arg Ser Asp Glu Leu Gln Arg His Lys Arg Thr 
            660                 665                 670         


His Thr Gly Glu Lys Lys Phe Ala Cys Pro Glu Cys Pro Lys Arg Phe 
        675                 680                 685             


Met Arg Ser Asp His Leu Ser Lys His Ile Lys Thr His Gln Asn Lys 
    690                 695                 700                 


Lys Gly Gly Pro Gly Val Ala Leu Ser Val Gly Thr Leu Pro Leu Asp 
705                 710                 715                 720 


Ser Gly Ala Gly Ser Glu Gly Ser Gly Thr Ala Thr Pro Ser Ala Leu 
                725                 730                 735     


Ile Thr Thr Asn Met Val Ala Met Glu Ala Ile Cys Pro Glu Gly Ile 
            740                 745                 750         


Ala Arg Leu Ala Asn Ser Gly Ile Asn Val Met Gln Val Ala Asp Leu 
        755                 760                 765             


Gln Ser Ile Asn Ile Ser Gly Asn Gly Phe 
    770                 775             


<210>  3477
<211>  666
<212>  PRT
<213>  homo sapiens

<400>  3477

Met Ala Met Thr Trp Ile Val Phe Ser Leu Trp Pro Leu Thr Val Phe 
1               5                   10                  15      


Met Gly His Ile Gly Gly His Ser Leu Phe Ser Cys Glu Pro Ile Thr 
            20                  25                  30          


Leu Arg Met Cys Gln Asp Leu Pro Tyr Asn Thr Thr Phe Met Pro Asn 
        35                  40                  45              


Leu Leu Asn His Tyr Asp Gln Gln Thr Ala Ala Leu Ala Met Glu Pro 
    50                  55                  60                  


Phe His Pro Met Val Asn Leu Asp Cys Ser Arg Asp Phe Arg Pro Phe 
65                  70                  75                  80  


Leu Cys Ala Leu Tyr Ala Pro Ile Cys Met Glu Tyr Gly Arg Val Thr 
                85                  90                  95      


Leu Pro Cys Arg Arg Leu Cys Gln Arg Ala Tyr Ser Glu Cys Ser Lys 
            100                 105                 110         


Leu Met Glu Met Phe Gly Val Pro Trp Pro Glu Asp Met Glu Cys Ser 
        115                 120                 125             


Arg Phe Pro Asp Cys Asp Glu Pro Tyr Pro Arg Leu Val Asp Leu Asn 
    130                 135                 140                 


Leu Ala Gly Glu Pro Thr Glu Gly Ala Pro Val Ala Val Gln Arg Asp 
145                 150                 155                 160 


Tyr Gly Phe Trp Cys Pro Arg Glu Leu Lys Ile Asp Pro Asp Leu Gly 
                165                 170                 175     


Tyr Ser Phe Leu His Val Arg Asp Cys Ser Pro Pro Cys Pro Asn Met 
            180                 185                 190         


Tyr Phe Arg Arg Glu Glu Leu Ser Phe Ala Arg Tyr Phe Ile Gly Leu 
        195                 200                 205             


Ile Ser Ile Ile Cys Leu Ser Ala Thr Leu Phe Thr Phe Leu Thr Phe 
    210                 215                 220                 


Leu Ile Asp Val Thr Arg Phe Arg Tyr Pro Glu Arg Pro Ile Ile Phe 
225                 230                 235                 240 


Tyr Ala Val Cys Tyr Met Met Val Ser Leu Ile Phe Phe Ile Gly Phe 
                245                 250                 255     


Leu Leu Glu Asp Arg Val Ala Cys Asn Ala Ser Ile Pro Ala Gln Tyr 
            260                 265                 270         


Lys Ala Ser Thr Val Thr Gln Gly Ser His Asn Lys Ala Cys Thr Met 
        275                 280                 285             


Leu Phe Met Ile Leu Tyr Phe Phe Thr Met Ala Gly Ser Val Trp Trp 
    290                 295                 300                 


Val Ile Leu Thr Ile Thr Trp Phe Leu Ala Ala Val Pro Lys Trp Gly 
305                 310                 315                 320 


Ser Glu Ala Ile Glu Lys Lys Ala Leu Leu Phe His Ala Ser Ala Trp 
                325                 330                 335     


Gly Ile Pro Gly Thr Leu Thr Ile Ile Leu Leu Ala Met Asn Lys Ile 
            340                 345                 350         


Glu Gly Asp Asn Ile Ser Gly Val Cys Phe Val Gly Leu Tyr Asp Val 
        355                 360                 365             


Asp Ala Leu Arg Tyr Phe Val Leu Ala Pro Leu Cys Leu Tyr Val Val 
    370                 375                 380                 


Val Gly Val Ser Leu Leu Leu Ala Gly Ile Ile Ser Leu Asn Arg Val 
385                 390                 395                 400 


Arg Ile Glu Ile Pro Leu Glu Lys Glu Asn Gln Asp Lys Leu Val Lys 
                405                 410                 415     


Phe Met Ile Arg Ile Gly Val Phe Ser Ile Leu Tyr Leu Val Pro Leu 
            420                 425                 430         


Leu Val Val Ile Gly Cys Tyr Phe Tyr Glu Gln Ala Tyr Arg Gly Ile 
        435                 440                 445             


Trp Glu Thr Thr Trp Ile Gln Glu Arg Cys Arg Glu Tyr His Ile Pro 
    450                 455                 460                 


Cys Pro Tyr Gln Val Thr Gln Met Ser Arg Pro Asp Leu Ile Leu Phe 
465                 470                 475                 480 


Leu Met Lys Tyr Leu Met Ala Leu Ile Val Gly Ile Pro Ser Val Phe 
                485                 490                 495     


Trp Val Gly Ser Lys Lys Thr Cys Phe Glu Trp Ala Ser Phe Phe His 
            500                 505                 510         


Gly Arg Arg Lys Lys Glu Ile Val Asn Glu Ser Arg Gln Val Leu Gln 
        515                 520                 525             


Glu Pro Asp Phe Ala Gln Ser Leu Leu Arg Asp Pro Asn Thr Pro Ile 
    530                 535                 540                 


Ile Arg Lys Ser Arg Gly Thr Ser Thr Gln Gly Thr Ser Thr His Ala 
545                 550                 555                 560 


Ser Ser Thr Gln Leu Ala Met Val Asp Asp Gln Arg Ser Lys Ala Gly 
                565                 570                 575     


Ser Ile His Ser Lys Val Ser Ser Tyr His Gly Ser Leu His Arg Ser 
            580                 585                 590         


Arg Asp Gly Arg Tyr Thr Pro Cys Ser Tyr Arg Gly Met Glu Glu Arg 
        595                 600                 605             


Leu Pro His Gly Ser Met Ser Arg Leu Thr Asp His Ser Arg His Ser 
    610                 615                 620                 


Ser Ser His Arg Leu Asn Glu Gln Ser Arg His Ser Ser Ile Arg Asp 
625                 630                 635                 640 


Leu Ser Asn Asn Pro Met Thr His Ile Thr His Gly Thr Ser Met Asn 
                645                 650                 655     


Arg Val Ile Glu Glu Asp Gly Thr Ser Ala 
            660                 665     


<210>  3478
<211>  531
<212>  PRT
<213>  homo sapiens

<400>  3478

Met Cys Pro Lys Gly Tyr Glu Asp Ser Met Glu Phe Pro Asp His Ser 
1               5                   10                  15      


Arg His Leu Leu Gln Cys Leu Ser Glu Gln Arg His Gln Gly Phe Leu 
            20                  25                  30          


Cys Asp Cys Thr Val Leu Val Gly Asp Ala Gln Phe Arg Ala His Arg 
        35                  40                  45              


Ala Val Leu Ala Ser Cys Ser Met Tyr Phe His Leu Phe Tyr Lys Asp 
    50                  55                  60                  


Gln Leu Asp Lys Arg Asp Ile Val His Leu Asn Ser Asp Ile Val Thr 
65                  70                  75                  80  


Ala Pro Ala Phe Ala Leu Leu Leu Glu Phe Met Tyr Glu Gly Lys Leu 
                85                  90                  95      


Gln Phe Lys Asp Leu Pro Ile Glu Asp Val Leu Ala Ala Ala Ser Tyr 
            100                 105                 110         


Leu His Met Tyr Asp Ile Val Lys Val Cys Lys Lys Lys Leu Lys Glu 
        115                 120                 125             


Lys Ala Thr Thr Glu Ala Asp Ser Thr Lys Lys Glu Glu Asp Ala Ser 
    130                 135                 140                 


Ser Cys Ser Asp Lys Val Glu Ser Leu Ser Asp Gly Ser Ser His Ile 
145                 150                 155                 160 


Ala Gly Asp Leu Pro Ser Asp Glu Asp Glu Gly Glu Asp Glu Lys Leu 
                165                 170                 175     


Asn Ile Leu Pro Ser Lys Arg Asp Leu Ala Ala Glu Pro Gly Asn Met 
            180                 185                 190         


Trp Met Arg Leu Pro Ser Asp Ser Ala Gly Ile Pro Gln Ala Gly Gly 
        195                 200                 205             


Glu Ala Glu Pro His Ala Thr Ala Ala Gly Lys Thr Val Ala Ser Pro 
    210                 215                 220                 


Cys Ser Ser Thr Glu Ser Leu Ser Gln Arg Ser Val Thr Ser Val Arg 
225                 230                 235                 240 


Asp Ser Ala Asp Val Asp Cys Val Leu Asp Leu Ser Val Lys Ser Ser 
                245                 250                 255     


Leu Ser Gly Val Glu Asn Leu Asn Ser Ser Tyr Phe Ser Ser Gln Asp 
            260                 265                 270         


Val Leu Arg Ser Asn Leu Val Gln Val Lys Val Glu Lys Glu Ala Ser 
        275                 280                 285             


Cys Asp Glu Ser Asp Val Gly Thr Asn Asp Tyr Asp Met Glu His Ser 
    290                 295                 300                 


Thr Val Lys Glu Ser Val Ser Thr Asn Asn Arg Val Gln Tyr Glu Pro 
305                 310                 315                 320 


Ala His Leu Ala Pro Leu Arg Glu Asp Ser Val Leu Arg Glu Leu Asp 
                325                 330                 335     


Arg Glu Asp Lys Ala Ser Asp Asp Glu Met Met Thr Pro Glu Ser Glu 
            340                 345                 350         


Arg Val Gln Val Glu Gly Gly Met Glu Ser Ser Leu Leu Pro Tyr Val 
        355                 360                 365             


Ser Asn Ile Leu Ser Pro Ala Gly Gln Ile Phe Met Cys Pro Leu Cys 
    370                 375                 380                 


Asn Lys Val Phe Pro Ser Pro His Ile Leu Gln Ile His Leu Ser Thr 
385                 390                 395                 400 


His Phe Arg Glu Gln Asp Gly Ile Arg Ser Lys Pro Ala Ala Asp Val 
                405                 410                 415     


Asn Val Pro Thr Cys Ser Leu Cys Gly Lys Thr Phe Ser Cys Met Tyr 
            420                 425                 430         


Thr Leu Lys Arg His Glu Arg Thr His Ser Gly Glu Lys Pro Tyr Thr 
        435                 440                 445             


Cys Thr Gln Cys Gly Lys Ser Phe Gln Tyr Ser His Asn Leu Ser Arg 
    450                 455                 460                 


His Ala Val Val His Thr Arg Glu Lys Pro His Ala Cys Lys Trp Cys 
465                 470                 475                 480 


Glu Arg Arg Phe Thr Gln Ser Gly Asp Leu Tyr Arg His Ile Arg Lys 
                485                 490                 495     


Phe His Cys Glu Leu Val Asn Ser Leu Ser Val Lys Ser Glu Ala Leu 
            500                 505                 510         


Ser Leu Pro Thr Val Arg Asp Trp Thr Leu Glu Asp Ser Ser Gln Glu 
        515                 520                 525             


Leu Trp Lys 
    530     


<210>  3479
<211>  683
<212>  PRT
<213>  homo sapiens

<400>  3479

Met Ala Ser Gly Pro Gly Ser Gln Glu Arg Glu Gly Leu Leu Ile Val 
1               5                   10                  15      


Lys Leu Glu Glu Asp Cys Ala Trp Ser Gln Glu Leu Pro Pro Pro Asp 
            20                  25                  30          


Pro Gly Pro Ser Pro Glu Ala Ser His Leu Arg Phe Arg Arg Phe Arg 
        35                  40                  45              


Phe Gln Glu Ala Ala Gly Pro Arg Glu Ala Leu Ser Arg Leu Gln Glu 
    50                  55                  60                  


Leu Cys His Gly Trp Leu Arg Pro Glu Met Arg Thr Lys Glu Gln Ile 
65                  70                  75                  80  


Leu Glu Leu Leu Val Leu Glu Gln Phe Leu Thr Ile Leu Pro Gln Glu 
                85                  90                  95      


Ile Gln Ser Arg Val Gln Glu Leu His Pro Glu Ser Gly Glu Glu Ala 
            100                 105                 110         


Val Thr Leu Val Glu Asp Met Gln Arg Glu Leu Gly Arg Leu Arg Gln 
        115                 120                 125             


Gln Val Thr Asn His Gly Arg Gly Thr Glu Val Leu Leu Glu Glu Pro 
    130                 135                 140                 


Leu Pro Leu Glu Thr Ala Arg Glu Ser Pro Ser Phe Lys Leu Glu Pro 
145                 150                 155                 160 


Met Glu Thr Glu Arg Ser Pro Gly Pro Arg Leu Gln Glu Leu Leu Gly 
                165                 170                 175     


Pro Ser Pro Gln Arg Asp Pro Gln Ala Val Lys Glu Arg Ala Leu Ser 
            180                 185                 190         


Ala Pro Trp Leu Ser Leu Phe Pro Pro Glu Gly Asn Met Glu Asp Lys 
        195                 200                 205             


Glu Met Thr Gly Pro Gln Leu Pro Glu Ser Leu Glu Asp Val Ala Met 
    210                 215                 220                 


Tyr Ile Ser Gln Glu Glu Trp Gly His Gln Asp Pro Ser Lys Arg Ala 
225                 230                 235                 240 


Leu Ser Arg Asp Thr Val Gln Glu Ser Tyr Glu Asn Val Asp Ser Leu 
                245                 250                 255     


Glu Ser His Ile Pro Ser Gln Glu Val Pro Gly Thr Gln Val Gly Gln 
            260                 265                 270         


Gly Gly Lys Leu Trp Asp Pro Ser Val Gln Ser Cys Lys Glu Gly Leu 
        275                 280                 285             


Ser Pro Arg Gly Pro Ala Pro Gly Glu Glu Lys Phe Glu Asn Leu Glu 
    290                 295                 300                 


Gly Val Pro Ser Val Cys Ser Glu Asn Ile His Pro Gln Val Leu Leu 
305                 310                 315                 320 


Pro Asp Gln Ala Arg Gly Glu Val Pro Trp Ser Pro Glu Leu Gly Arg 
                325                 330                 335     


Pro His Asp Arg Ser Gln Gly Asp Trp Ala Pro Pro Pro Glu Gly Gly 
            340                 345                 350         


Met Glu Gln Ala Leu Ala Gly Ala Ser Ser Gly Arg Glu Leu Gly Arg 
        355                 360                 365             


Pro Lys Glu Leu Gln Pro Lys Lys Leu His Leu Cys Pro Leu Cys Gly 
    370                 375                 380                 


Lys Asn Phe Ser Asn Asn Ser Asn Leu Ile Arg His Gln Arg Ile His 
385                 390                 395                 400 


Ala Ala Glu Arg Leu Cys Met Gly Val Asp Cys Thr Glu Ile Phe Gly 
                405                 410                 415     


Gly Asn Pro Arg Phe Leu Ser Leu His Arg Ala His Leu Gly Glu Glu 
            420                 425                 430         


Ala His Lys Cys Leu Glu Cys Gly Lys Cys Phe Ser Gln Asn Thr His 
        435                 440                 445             


Leu Thr Arg His Gln Arg Thr His Thr Gly Glu Lys Pro Tyr Gln Cys 
    450                 455                 460                 


Asn Ile Cys Gly Lys Cys Phe Ser Cys Asn Ser Asn Leu His Arg His 
465                 470                 475                 480 


Gln Arg Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Pro Glu Cys Gly 
                485                 490                 495     


Glu Ile Phe Ala His Ser Ser Asn Leu Leu Arg His Gln Arg Ile His 
            500                 505                 510         


Thr Gly Glu Arg Pro Tyr Lys Cys Pro Glu Cys Gly Lys Ser Phe Ser 
        515                 520                 525             


Arg Ser Ser His Leu Val Ile His Glu Arg Thr His Glu Arg Glu Arg 
    530                 535                 540                 


Leu Tyr Pro Phe Ser Glu Cys Gly Glu Ala Val Ser Asp Ser Thr Pro 
545                 550                 555                 560 


Phe Leu Thr Asn His Gly Ala His Lys Ala Glu Lys Lys Leu Phe Glu 
                565                 570                 575     


Cys Leu Thr Cys Gly Lys Ser Phe Arg Gln Gly Met His Leu Thr Arg 
            580                 585                 590         


His Gln Arg Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Thr Leu Cys 
        595                 600                 605             


Gly Glu Asn Phe Ser His Arg Ser Asn Leu Ile Arg His Gln Arg Ile 
    610                 615                 620                 


His Thr Gly Glu Lys Pro Tyr Thr Cys His Glu Cys Gly Asp Ser Phe 
625                 630                 635                 640 


Ser His Ser Ser Asn Arg Ile Arg His Leu Arg Thr His Thr Gly Glu 
                645                 650                 655     


Arg Pro Tyr Lys Cys Ser Glu Cys Gly Glu Ser Phe Ser Arg Ser Ser 
            660                 665                 670         


Arg Leu Met Ser His Gln Arg Thr His Thr Gly 
        675                 680             


<210>  3480
<211>  252
<212>  PRT
<213>  homo sapiens

<400>  3480

Met Phe Gln Pro Ala Pro Lys Arg Cys Phe Thr Ile Glu Ser Leu Val 
1               5                   10                  15      


Ala Lys Asp Ser Pro Leu Pro Ala Ser Arg Ser Glu Asp Pro Ile Arg 
            20                  25                  30          


Pro Ala Ala Leu Ser Tyr Ala Asn Ser Ser Pro Ile Asn Pro Phe Leu 
        35                  40                  45              


Asn Gly Phe His Ser Ala Ala Ala Ala Ala Ala Gly Arg Gly Val Tyr 
    50                  55                  60                  


Ser Asn Pro Asp Leu Val Phe Ala Glu Ala Val Ser His Pro Pro Asn 
65                  70                  75                  80  


Pro Ala Val Pro Val His Pro Val Pro Pro Pro His Ala Leu Ala Ala 
                85                  90                  95      


His Pro Leu Pro Ser Ser His Ser Pro His Pro Leu Phe Ala Ser Gln 
            100                 105                 110         


Gln Arg Asp Pro Ser Thr Phe Tyr Pro Trp Leu Ile His Arg Tyr Arg 
        115                 120                 125             


Tyr Leu Gly His Arg Phe Gln Gly Asn Asp Thr Ser Pro Glu Ser Phe 
    130                 135                 140                 


Leu Leu His Asn Ala Leu Ala Arg Lys Pro Lys Arg Ile Arg Thr Ala 
145                 150                 155                 160 


Phe Ser Pro Ser Gln Leu Leu Arg Leu Glu His Ala Phe Glu Lys Asn 
                165                 170                 175     


His Tyr Val Val Gly Ala Glu Arg Lys Gln Leu Ala His Ser Leu Ser 
            180                 185                 190         


Leu Thr Glu Thr Gln Val Lys Val Trp Phe Gln Asn Arg Arg Thr Lys 
        195                 200                 205             


Phe Lys Arg Gln Lys Leu Glu Glu Glu Gly Ser Asp Ser Gln Gln Lys 
    210                 215                 220                 


Lys Lys Gly Thr His His Ile Asn Arg Trp Arg Ile Ala Thr Lys Gln 
225                 230                 235                 240 


Ala Ser Pro Glu Glu Ile Asp Val Thr Ser Asp Asp 
                245                 250         


<210>  3481
<211>  361
<212>  PRT
<213>  homo sapiens

<400>  3481

Met Leu Lys Arg Cys Gly Arg Arg Leu Leu Leu Ala Leu Ala Gly Ala 
1               5                   10                  15      


Leu Leu Ala Cys Leu Leu Val Leu Thr Ala Asp Pro Pro Pro Pro Pro 
            20                  25                  30          


Leu Pro Ala Glu Arg Gly Arg Arg Ala Leu Arg Ser Leu Ala Gly Pro 
        35                  40                  45              


Ala Gly Ala Ala Pro Ala Pro Gly Leu Gly Ala Ala Ala Ala Ala Pro 
    50                  55                  60                  


Gly Ala Leu Val Arg Asp Val His Ser Leu Ser Glu Tyr Phe Ser Leu 
65                  70                  75                  80  


Leu Thr Arg Ala Arg Arg Asp Ala Gly Pro Pro Pro Gly Ala Ala Pro 
                85                  90                  95      


Arg Pro Ala Asp Gly His Pro Arg Pro Leu Ala Glu Pro Leu Ala Pro 
            100                 105                 110         


Arg Asp Val Phe Ile Ala Val Lys Thr Thr Lys Lys Phe His Arg Ala 
        115                 120                 125             


Arg Leu Asp Leu Leu Leu Glu Thr Trp Ile Ser Arg His Lys Glu Met 
    130                 135                 140                 


Thr Phe Ile Phe Thr Asp Gly Glu Asp Glu Ala Leu Ala Arg His Thr 
145                 150                 155                 160 


Gly Asn Val Val Ile Thr Asn Cys Ser Ala Ala His Ser Arg Gln Ala 
                165                 170                 175     


Leu Ser Cys Lys Met Ala Val Glu Tyr Asp Arg Phe Ile Glu Ser Gly 
            180                 185                 190         


Arg Lys Trp Phe Cys His Val Asp Asp Asp Asn Tyr Val Asn Leu Arg 
        195                 200                 205             


Ala Leu Leu Arg Leu Leu Ala Ser Tyr Pro His Thr Arg Asp Val Tyr 
    210                 215                 220                 


Val Gly Lys Pro Ser Leu Asp Arg Pro Ile Gln Ala Met Glu Arg Val 
225                 230                 235                 240 


Ser Glu Asn Lys Val Arg Pro Val His Phe Trp Phe Ala Thr Gly Gly 
                245                 250                 255     


Ala Gly Phe Cys Ile Ser Arg Gly Leu Ala Leu Lys Met Ser Pro Trp 
            260                 265                 270         


Ala Ser Gly Gly His Phe Met Asn Thr Ala Glu Arg Ile Arg Leu Pro 
        275                 280                 285             


Asp Asp Cys Thr Ile Gly Tyr Ile Val Glu Ala Leu Leu Gly Val Pro 
    290                 295                 300                 


Leu Ile Arg Ser Gly Leu Phe His Ser His Leu Glu Asn Leu Gln Gln 
305                 310                 315                 320 


Val Pro Thr Ser Glu Leu His Glu Gln Val Thr Leu Ser Tyr Gly Met 
                325                 330                 335     


Phe Glu Asn Lys Arg Asn Ala Val His Val Lys Gly Pro Phe Ser Val 
            340                 345                 350         


Glu Ala Asp Pro Ser Arg Trp Gly Asn 
        355                 360     


<210>  3482
<211>  388
<212>  PRT
<213>  homo sapiens

<400>  3482

Met Asp Gly Val Gly Val Pro Ala Ser Met Tyr Gly Asp Pro His Ala 
1               5                   10                  15      


Pro Arg Pro Ile Pro Pro Val His His Leu Asn His Gly Pro Pro Leu 
            20                  25                  30          


His Ala Thr Gln His Tyr Gly Ala His Ala Pro His Pro Asn Val Met 
        35                  40                  45              


Pro Ala Ser Met Gly Ser Ala Val Asn Asp Ala Leu Lys Arg Asp Lys 
    50                  55                  60                  


Asp Ala Ile Tyr Gly His Pro Leu Phe Pro Leu Leu Ala Leu Val Phe 
65                  70                  75                  80  


Glu Lys Cys Glu Leu Ala Thr Cys Thr Pro Arg Glu Pro Gly Val Ala 
                85                  90                  95      


Gly Gly Asp Val Cys Ser Ser Asp Ser Phe Asn Glu Asp Ile Ala Val 
            100                 105                 110         


Phe Ala Lys Gln Val Arg Ala Glu Lys Pro Leu Phe Ser Ser Asn Pro 
        115                 120                 125             


Glu Leu Asp Asn Leu Met Ile Gln Ala Ile Gln Val Leu Arg Phe His 
    130                 135                 140                 


Leu Leu Glu Leu Glu Lys Val His Glu Leu Cys Asp Asn Phe Cys His 
145                 150                 155                 160 


Arg Tyr Ile Ser Cys Leu Lys Gly Lys Met Pro Ile Asp Leu Val Ile 
                165                 170                 175     


Asp Glu Arg Asp Gly Ser Ser Lys Ser Asp His Glu Glu Leu Ser Gly 
            180                 185                 190         


Ser Ser Thr Asn Leu Ala Asp His Asn Pro Ser Ser Trp Arg Asp His 
        195                 200                 205             


Asp Asp Ala Thr Ser Thr His Ser Ala Gly Thr Pro Gly Pro Ser Ser 
    210                 215                 220                 


Gly Gly His Ala Ser Gln Ser Gly Asp Asn Ser Ser Glu Gln Gly Asp 
225                 230                 235                 240 


Gly Leu Asp Asn Ser Val Ala Ser Pro Gly Thr Gly Asp Asp Asp Asp 
                245                 250                 255     


Pro Asp Lys Asp Lys Lys Arg Gln Lys Lys Arg Gly Ile Phe Pro Lys 
            260                 265                 270         


Val Ala Thr Asn Ile Met Arg Ala Trp Leu Phe Gln His Leu Thr His 
        275                 280                 285             


Pro Tyr Pro Ser Glu Glu Gln Lys Lys Gln Leu Ala Gln Asp Thr Gly 
    290                 295                 300                 


Leu Thr Ile Leu Gln Val Asn Asn Trp Phe Ile Asn Ala Arg Arg Arg 
305                 310                 315                 320 


Ile Val Gln Pro Met Ile Asp Gln Ser Asn Arg Ala Gly Phe Leu Leu 
                325                 330                 335     


Asp Pro Ser Val Ser Gln Gly Ala Ala Tyr Ser Pro Glu Gly Gln Pro 
            340                 345                 350         


Met Gly Ser Phe Val Leu Asp Gly Gln Gln His Met Gly Ile Arg Pro 
        355                 360                 365             


Ala Gly Pro Met Ser Gly Met Gly Met Asn Met Gly Met Asp Gly Gln 
    370                 375                 380                 


Trp His Tyr Met 
385             


<210>  3483
<211>  306
<212>  PRT
<213>  homo sapiens

<400>  3483

Met Ala Leu Val Phe Glu Lys Cys Glu Leu Ala Thr Cys Thr Pro Arg 
1               5                   10                  15      


Glu Pro Gly Val Ala Gly Gly Asp Val Cys Ser Ser Asp Ser Phe Asn 
            20                  25                  30          


Glu Asp Ile Ala Val Phe Ala Lys Gln Val Arg Ala Glu Lys Pro Leu 
        35                  40                  45              


Phe Ser Ser Asn Pro Glu Leu Asp Asn Leu Met Ile Gln Ala Ile Gln 
    50                  55                  60                  


Val Leu Arg Phe His Leu Leu Glu Leu Glu Lys Val His Glu Leu Cys 
65                  70                  75                  80  


Asp Asn Phe Cys His Arg Tyr Ile Ser Cys Leu Lys Gly Lys Met Pro 
                85                  90                  95      


Ile Asp Leu Val Ile Asp Glu Arg Asp Gly Ser Ser Lys Ser Asp His 
            100                 105                 110         


Glu Glu Leu Ser Gly Ser Ser Thr Asn Leu Ala Asp His Asn Pro Ser 
        115                 120                 125             


Ser Trp Arg Asp His Asp Asp Ala Thr Ser Thr His Ser Ala Gly Thr 
    130                 135                 140                 


Pro Gly Pro Ser Ser Gly Gly His Ala Ser Gln Ser Gly Asp Asn Ser 
145                 150                 155                 160 


Ser Glu Gln Gly Asp Gly Leu Asp Asn Ser Val Ala Ser Pro Gly Thr 
                165                 170                 175     


Gly Asp Asp Asp Asp Pro Asp Lys Asp Lys Lys Arg Gln Lys Lys Arg 
            180                 185                 190         


Gly Ile Phe Pro Lys Val Ala Thr Asn Ile Met Arg Ala Trp Leu Phe 
        195                 200                 205             


Gln His Leu Thr His Pro Tyr Pro Ser Glu Glu Gln Lys Lys Gln Leu 
    210                 215                 220                 


Ala Gln Asp Thr Gly Leu Thr Ile Leu Gln Val Asn Asn Trp Phe Ile 
225                 230                 235                 240 


Asn Ala Arg Arg Arg Ile Val Gln Pro Met Ile Asp Gln Ser Asn Arg 
                245                 250                 255     


Ala Val Ser Gln Gly Ala Ala Tyr Ser Pro Glu Gly Gln Pro Met Gly 
            260                 265                 270         


Ser Phe Val Leu Asp Gly Gln Gln His Met Gly Ile Arg Pro Ala Gly 
        275                 280                 285             


Pro Met Ser Gly Met Gly Met Asn Met Gly Met Asp Gly Gln Trp His 
    290                 295                 300                 


Tyr Met 
305     


<210>  3484
<211>  155
<212>  PRT
<213>  homo sapiens

<400>  3484

Met Arg His Leu Pro Tyr Phe Cys Arg Gly Gln Val Val Arg Gly Phe 
1               5                   10                  15      


Gly Arg Gly Ser Lys Gln Leu Gly Ile Pro Thr Ala Asn Phe Pro Glu 
            20                  25                  30          


Gln Val Val Asp Asn Leu Pro Ala Asp Ile Ser Thr Gly Ile Tyr Tyr 
        35                  40                  45              


Gly Trp Ala Ser Val Gly Ser Gly Asp Val His Lys Met Val Val Ser 
    50                  55                  60                  


Ile Gly Trp Asn Pro Tyr Tyr Lys Asn Thr Lys Lys Ser Met Glu Thr 
65                  70                  75                  80  


His Ile Met His Thr Phe Lys Glu Asp Phe Tyr Gly Glu Ile Leu Asn 
                85                  90                  95      


Val Ala Ile Val Gly Tyr Leu Arg Pro Glu Lys Asn Phe Asp Ser Leu 
            100                 105                 110         


Glu Ser Leu Ile Ser Ala Ile Gln Gly Asp Ile Glu Glu Ala Lys Lys 
        115                 120                 125             


Arg Leu Glu Leu Pro Glu His Leu Lys Ile Lys Glu Asp Asn Phe Phe 
    130                 135                 140                 


Gln Val Ser Lys Ser Lys Ile Met Asn Gly His 
145                 150                 155 


<210>  3485
<211>  735
<212>  PRT
<213>  homo sapiens

<400>  3485

Met His Cys Gly Leu Leu Glu Glu Pro Asp Met Asp Ser Thr Glu Ser 
1               5                   10                  15      


Trp Ile Glu Arg Cys Leu Asn Glu Ser Glu Asn Lys Arg Tyr Ser Ser 
            20                  25                  30          


His Thr Ser Leu Gly Asn Val Ser Asn Asp Glu Asn Glu Glu Lys Glu 
        35                  40                  45              


Asn Asn Arg Ala Ser Lys Pro His Ser Thr Pro Ala Thr Leu Gln Trp 
    50                  55                  60                  


Leu Glu Glu Asn Tyr Glu Ile Ala Glu Gly Val Cys Ile Pro Arg Ser 
65                  70                  75                  80  


Ala Leu Tyr Met His Tyr Leu Asp Phe Cys Glu Lys Asn Asp Thr Gln 
                85                  90                  95      


Pro Val Asn Ala Ala Ser Phe Gly Lys Ile Ile Arg Gln Gln Phe Pro 
            100                 105                 110         


Gln Leu Thr Thr Arg Arg Leu Gly Thr Arg Gly Gln Ser Lys Tyr His 
        115                 120                 125             


Tyr Tyr Gly Ile Ala Val Lys Glu Ser Ser Gln Tyr Tyr Asp Val Met 
    130                 135                 140                 


Tyr Ser Lys Lys Gly Ala Ala Trp Val Ser Glu Thr Gly Lys Lys Glu 
145                 150                 155                 160 


Val Ser Lys Gln Thr Val Ala Tyr Ser Pro Arg Ser Lys Leu Gly Thr 
                165                 170                 175     


Leu Leu Pro Glu Phe Pro Asn Val Lys Asp Leu Asn Leu Pro Ala Ser 
            180                 185                 190         


Leu Pro Glu Glu Lys Val Ser Thr Phe Ile Met Met Tyr Arg Thr His 
        195                 200                 205             


Cys Gln Arg Ile Leu Asp Thr Val Ile Arg Ala Asn Phe Asp Glu Val 
    210                 215                 220                 


Gln Ser Phe Leu Leu His Phe Trp Gln Gly Met Pro Pro His Met Leu 
225                 230                 235                 240 


Pro Val Leu Gly Ser Ser Thr Val Val Asn Ile Val Gly Val Cys Asp 
                245                 250                 255     


Ser Ile Leu Tyr Lys Ala Ile Ser Gly Val Leu Met Pro Thr Val Leu 
            260                 265                 270         


Gln Ala Leu Pro Asp Ser Leu Thr Gln Val Ile Arg Lys Phe Ala Lys 
        275                 280                 285             


Gln Leu Asp Glu Trp Leu Lys Val Ala Leu His Asp Leu Pro Glu Asn 
    290                 295                 300                 


Leu Arg Asn Ile Lys Phe Glu Leu Ser Arg Arg Phe Ser Gln Ile Leu 
305                 310                 315                 320 


Arg Arg Gln Thr Ser Leu Asn His Leu Cys Gln Ala Ser Arg Thr Val 
                325                 330                 335     


Ile His Ser Ala Asp Ile Thr Phe Gln Met Leu Glu Asp Trp Arg Asn 
            340                 345                 350         


Val Asp Leu Asn Ser Ile Thr Lys Gln Thr Leu Tyr Thr Met Glu Asp 
        355                 360                 365             


Ser Arg Asp Glu His Arg Lys Leu Ile Thr Gln Leu Tyr Gln Glu Phe 
    370                 375                 380                 


Asp His Leu Leu Glu Glu Gln Ser Pro Ile Glu Ser Tyr Ile Glu Trp 
385                 390                 395                 400 


Leu Asp Thr Met Val Asp Arg Cys Val Val Lys Val Ala Ala Lys Arg 
                405                 410                 415     


Gln Gly Ser Leu Lys Lys Val Ala Gln Gln Phe Leu Leu Met Trp Ser 
            420                 425                 430         


Cys Phe Gly Thr Arg Val Ile Arg Asp Met Thr Leu His Ser Ala Pro 
        435                 440                 445             


Ser Phe Gly Ser Phe His Leu Ile His Leu Met Phe Asp Asp Tyr Val 
    450                 455                 460                 


Leu Tyr Leu Leu Glu Ser Leu His Cys Gln Glu Arg Ala Asn Glu Leu 
465                 470                 475                 480 


Met Arg Ala Met Lys Gly Glu Gly Ser Thr Ala Glu Val Arg Glu Glu 
                485                 490                 495     


Ile Ile Leu Thr Glu Ala Ala Ala Pro Thr Pro Ser Pro Val Pro Ser 
            500                 505                 510         


Phe Ser Pro Ala Lys Ser Ala Thr Ser Val Glu Val Pro Pro Pro Ser 
        515                 520                 525             


Ser Pro Val Ser Asn Pro Ser Pro Glu Tyr Thr Gly Leu Ser Thr Thr 
    530                 535                 540                 


Gly Ala Met Gln Ser Tyr Thr Trp Ser Leu Thr Tyr Thr Val Thr Thr 
545                 550                 555                 560 


Ala Ala Gly Ser Pro Ala Glu Asn Ser Gln Gln Leu Pro Cys Met Arg 
                565                 570                 575     


Asn Thr His Val Pro Ser Ser Ser Val Thr His Arg Ile Pro Val Tyr 
            580                 585                 590         


Pro His Arg Glu Glu His Gly Tyr Thr Gly Ser Tyr Asn Tyr Gly Ser 
        595                 600                 605             


Tyr Gly Asn Gln His Pro His Pro Met Gln Ser Gln Tyr Pro Ala Leu 
    610                 615                 620                 


Pro His Asp Thr Ala Ile Ser Gly Pro Leu His Tyr Ala Pro Tyr His 
625                 630                 635                 640 


Arg Ser Ser Ala Gln Tyr Pro Phe Asn Ser Pro Thr Ser Arg Met Glu 
                645                 650                 655     


Pro Cys Leu Met Ser Ser Thr Pro Arg Leu His Pro Thr Pro Val Thr 
            660                 665                 670         


Pro Arg Trp Pro Glu Val Pro Ser Ala Asn Thr Cys Tyr Thr Ser Pro 
        675                 680                 685             


Ser Val His Ser Ala Arg Tyr Gly Asn Ser Ser Asp Met Tyr Thr Pro 
    690                 695                 700                 


Leu Thr Thr Arg Arg Asn Ser Glu Tyr Glu His Met Gln His Phe Pro 
705                 710                 715                 720 


Gly Phe Ala Tyr Ile Asn Gly Glu Ala Ser Thr Gly Trp Ala Lys 
                725                 730                 735 


<210>  3486
<211>  359
<212>  PRT
<213>  homo sapiens

<400>  3486

Met Thr Ser Thr Ser Lys Gly Ile Leu Arg Pro Phe Leu Ile Val Cys 
1               5                   10                  15      


Ile Ile Leu Gly Cys Phe Met Ala Cys Leu Leu Ile Tyr Ile Lys Pro 
            20                  25                  30          


Thr Asn Ser Trp Ile Phe Ser Pro Met Glu Ser Ala Ser Ser Val Leu 
        35                  40                  45              


Lys Met Lys Asn Phe Phe Ser Thr Lys Thr Asp Tyr Phe Asn Glu Thr 
    50                  55                  60                  


Thr Ile Leu Val Trp Val Trp Pro Phe Gly Gln Thr Phe Asp Leu Thr 
65                  70                  75                  80  


Ser Cys Gln Ala Met Phe Asn Ile Gln Gly Cys His Leu Thr Thr Asp 
                85                  90                  95      


Arg Ser Leu Tyr Asn Lys Ser His Ala Val Leu Ile His His Arg Asp 
            100                 105                 110         


Ile Ser Trp Asp Leu Thr Asn Leu Pro Gln Gln Ala Arg Pro Pro Phe 
        115                 120                 125             


Gln Lys Trp Ile Trp Met Asn Leu Glu Ser Pro Thr His Thr Pro Gln 
    130                 135                 140                 


Lys Ser Gly Ile Glu His Leu Phe Asn Leu Thr Leu Thr Tyr Arg Arg 
145                 150                 155                 160 


Asp Ser Asp Ile Gln Val Pro Tyr Gly Phe Leu Thr Val Ser Thr Asn 
                165                 170                 175     


Pro Phe Val Phe Glu Val Pro Ser Lys Glu Lys Leu Val Cys Trp Val 
            180                 185                 190         


Val Ser Asn Trp Asn Pro Glu His Ala Arg Val Lys Tyr Tyr Asn Glu 
        195                 200                 205             


Leu Ser Lys Ser Ile Glu Ile His Thr Tyr Gly Gln Ala Phe Gly Glu 
    210                 215                 220                 


Tyr Val Asn Asp Lys Asn Leu Ile Pro Thr Ile Ser Thr Cys Lys Phe 
225                 230                 235                 240 


Tyr Leu Ser Phe Glu Asn Ser Ile His Lys Asp Tyr Ile Thr Glu Lys 
                245                 250                 255     


Leu Tyr Asn Ala Phe Leu Ala Gly Ser Val Pro Val Val Leu Gly Pro 
            260                 265                 270         


Ser Arg Glu Asn Tyr Glu Asn Tyr Ile Pro Ala Asp Ser Phe Ile His 
        275                 280                 285             


Val Glu Asp Tyr Asn Ser Pro Ser Glu Leu Ala Lys Tyr Leu Lys Glu 
    290                 295                 300                 


Val Asp Lys Asn Asn Lys Leu Tyr Leu Ser Tyr Phe Asn Trp Arg Lys 
305                 310                 315                 320 


Asp Phe Thr Val Asn Leu Pro Arg Phe Trp Glu Ser His Ala Cys Leu 
                325                 330                 335     


Ala Cys Asp His Val Lys Arg His Gln Glu Tyr Lys Ser Val Gly Asn 
            340                 345                 350         


Leu Glu Lys Trp Phe Trp Asn 
        355                 


<210>  3487
<211>  95
<212>  PRT
<213>  homo sapiens

<400>  3487

Met Glu Leu Val Leu Val Phe Leu Cys Ser Leu Leu Ala Pro Met Val 
1               5                   10                  15      


Leu Ala Ser Ala Ala Glu Lys Glu Lys Glu Met Asp Pro Phe His Tyr 
            20                  25                  30          


Asp Tyr Gln Thr Leu Arg Ile Gly Gly Leu Val Phe Ala Val Val Leu 
        35                  40                  45              


Phe Ser Val Gly Ile Leu Leu Ile Leu Ser Arg Arg Cys Lys Cys Ser 
    50                  55                  60                  


Phe Asn Gln Lys Pro Arg Ala Pro Gly Asp Glu Glu Ala Gln Val Glu 
65                  70                  75                  80  


Asn Leu Ile Thr Ala Asn Ala Thr Glu Pro Gln Lys Ala Glu Asn 
                85                  90                  95  


<210>  3488
<211>  95
<212>  PRT
<213>  homo sapiens

<400>  3488

Met Glu Leu Val Leu Val Phe Leu Cys Ser Leu Leu Ala Pro Met Val 
1               5                   10                  15      


Leu Ala Ser Ala Ala Glu Lys Glu Lys Glu Met Asp Pro Phe His Tyr 
            20                  25                  30          


Asp Tyr Gln Thr Leu Arg Ile Gly Gly Leu Val Phe Ala Val Val Leu 
        35                  40                  45              


Phe Ser Val Gly Ile Leu Leu Ile Leu Ser Arg Arg Cys Lys Cys Ser 
    50                  55                  60                  


Phe Asn Gln Lys Pro Arg Ala Pro Gly Asp Glu Glu Ala Gln Val Glu 
65                  70                  75                  80  


Asn Leu Ile Thr Ala Asn Ala Thr Glu Pro Gln Lys Ala Glu Asn 
                85                  90                  95  


<210>  3489
<211>  95
<212>  PRT
<213>  homo sapiens

<400>  3489

Met Glu Leu Val Leu Val Phe Leu Cys Ser Leu Leu Ala Pro Met Val 
1               5                   10                  15      


Leu Ala Ser Ala Ala Glu Lys Glu Lys Glu Met Asp Pro Phe His Tyr 
            20                  25                  30          


Asp Tyr Gln Thr Leu Arg Ile Gly Gly Leu Val Phe Ala Val Val Leu 
        35                  40                  45              


Phe Ser Val Gly Ile Leu Leu Ile Leu Ser Arg Arg Cys Lys Cys Ser 
    50                  55                  60                  


Phe Asn Gln Lys Pro Arg Ala Pro Gly Asp Glu Glu Ala Gln Val Glu 
65                  70                  75                  80  


Asn Leu Ile Thr Ala Asn Ala Thr Glu Pro Gln Lys Ala Glu Asn 
                85                  90                  95  


<210>  3490
<211>  345
<212>  PRT
<213>  homo sapiens

<400>  3490

Met Leu Met Phe Asp Pro Val Pro Val Lys Gln Glu Ala Met Asp Pro 
1               5                   10                  15      


Val Ser Val Ser Tyr Pro Ser Asn Tyr Met Glu Ser Met Lys Pro Asn 
            20                  25                  30          


Lys Tyr Gly Val Ile Tyr Ser Thr Pro Leu Pro Glu Lys Phe Phe Gln 
        35                  40                  45              


Thr Pro Glu Gly Leu Ser His Gly Ile Gln Met Glu Pro Val Asp Leu 
    50                  55                  60                  


Thr Val Asn Lys Arg Ser Ser Pro Pro Ser Ala Gly Asn Ser Pro Ser 
65                  70                  75                  80  


Ser Leu Lys Phe Pro Ser Ser His Arg Arg Ala Ser Pro Gly Leu Ser 
                85                  90                  95      


Met Pro Ser Ser Ser Pro Pro Ile Lys Lys Tyr Ser Pro Pro Ser Pro 
            100                 105                 110         


Gly Val Gln Pro Phe Gly Val Pro Leu Ser Met Pro Pro Val Met Ala 
        115                 120                 125             


Ala Ala Leu Ser Arg His Gly Ile Arg Ser Pro Gly Ile Leu Pro Val 
    130                 135                 140                 


Ile Gln Pro Val Val Val Gln Pro Val Pro Phe Met Tyr Thr Ser His 
145                 150                 155                 160 


Leu Gln Gln Pro Leu Met Val Ser Leu Ser Glu Glu Met Glu Asn Ser 
                165                 170                 175     


Ser Ser Ser Met Gln Val Pro Val Ile Glu Ser Tyr Glu Lys Pro Ile 
            180                 185                 190         


Ser Gln Lys Lys Ile Lys Ile Glu Pro Gly Ile Glu Pro Gln Arg Thr 
        195                 200                 205             


Asp Tyr Tyr Pro Glu Glu Met Ser Pro Pro Leu Met Asn Ser Val Ser 
    210                 215                 220                 


Pro Pro Gln Ala Leu Leu Gln Glu Asn His Pro Ser Val Ile Val Gln 
225                 230                 235                 240 


Pro Gly Lys Arg Pro Leu Pro Val Glu Ser Pro Asp Thr Gln Arg Lys 
                245                 250                 255     


Arg Arg Ile His Arg Cys Asp Tyr Asp Gly Cys Asn Lys Val Tyr Thr 
            260                 265                 270         


Lys Ser Ser His Leu Lys Ala His Arg Arg Thr His Thr Gly Glu Lys 
        275                 280                 285             


Pro Tyr Lys Cys Thr Trp Glu Gly Cys Thr Trp Lys Phe Ala Arg Ser 
    290                 295                 300                 


Asp Glu Leu Thr Arg His Phe Arg Lys His Thr Gly Ile Lys Pro Phe 
305                 310                 315                 320 


Gln Cys Pro Asp Cys Asp Arg Ser Phe Ser Arg Ser Asp His Leu Ala 
                325                 330                 335     


Leu His Arg Lys Arg His Met Leu Val 
            340                 345 


<210>  3491
<211>  1210
<212>  PRT
<213>  homo sapiens

<400>  3491

Met Glu Glu His Ser Tyr Ile Gln Lys Glu Leu Asp Leu Gln Asn Gly 
1               5                   10                  15      


Ser Leu Glu Glu Asp Ser Val Val His Ser Val Glu Asn Asp Ser Gln 
            20                  25                  30          


Asn Met Met Glu Ser Leu Ser Pro Lys Lys Tyr Ser Ser Ser Leu Arg 
        35                  40                  45              


Phe Lys Ala Asn Gly Asp Tyr Ser Gly Ser Tyr Leu Thr Leu Ser Gln 
    50                  55                  60                  


Pro Val Pro Ala Lys Arg Ser Pro Ser Pro Leu Gly Thr Ser Val Arg 
65                  70                  75                  80  


Ser Ser Pro Ser Leu Ala Lys Ile Gln Gly Ser Lys Gln Phe Ser Tyr 
                85                  90                  95      


Asp Gly Thr Asp Lys Asn Ile Pro Met Lys Pro Pro Thr Pro Leu Leu 
            100                 105                 110         


Asn Thr Thr Ser Ser Leu Ser Gly Tyr Pro Leu Gly Arg Ala Asp Phe 
        115                 120                 125             


Asp His Tyr Thr Gly Arg Asp Ser Glu Arg Ala Leu Arg Leu Ser Glu 
    130                 135                 140                 


Lys Pro Pro Tyr Ser Lys Tyr Ser Ser Arg His Lys Ser His Asp Asn 
145                 150                 155                 160 


Val Tyr Ser Leu Gly Gly Leu Glu Gly Arg Lys Ala Ser Gly Ser Leu 
                165                 170                 175     


Leu Ala Met Trp Asn Gly Ser Ser Leu Ser Asp Ala Gly Pro Pro Pro 
            180                 185                 190         


Ile Ser Arg Ser Gly Ala Ala Ser Met Pro Ser Ser Pro Lys Gln Ala 
        195                 200                 205             


Arg Lys Met Ser Ile Gln Asp Ser Leu Ala Leu Gln Pro Lys Leu Thr 
    210                 215                 220                 


Arg His Lys Glu Leu Ala Ser Glu Asn Ile Asn Leu Arg Thr Arg Lys 
225                 230                 235                 240 


Tyr Ser Ser Ser Ser Leu Ser His Met Gly Ala Tyr Ser Arg Ser Leu 
                245                 250                 255     


Pro Arg Leu Tyr Arg Ala Thr Glu Asn Gln Leu Thr Pro Leu Ser Leu 
            260                 265                 270         


Pro Pro Arg Asn Ser Leu Gly Asn Ser Lys Arg Thr Lys Leu Gly Glu 
        275                 280                 285             


Lys Asp Leu Pro His Ser Val Ile Asp Asn Asp Asn Tyr Leu Asn Phe 
    290                 295                 300                 


Ser Ser Leu Ser Ser Gly Ala Leu Pro Tyr Lys Thr Ser Ala Ser Glu 
305                 310                 315                 320 


Gly Asn Pro Tyr Val Ser Ser Thr Leu Ser Val Pro Ala Ser Pro Arg 
                325                 330                 335     


Val Ala Arg Lys Met Leu Leu Ala Ser Thr Ser Ser Cys Ala Ser Asp 
            340                 345                 350         


Asp Phe Asp Gln Ala Ser Tyr Val Gly Thr Asn Pro Ser His Ser Leu 
        355                 360                 365             


Leu Ala Gly Glu Ser Asp Arg Val Phe Ala Thr Arg Arg Asn Phe Ser 
    370                 375                 380                 


Cys Gly Ser Val Glu Phe Asp Glu Ala Asp Leu Glu Ser Leu Arg Gln 
385                 390                 395                 400 


Ala Ser Gly Thr Pro Gln Pro Ala Leu Arg Glu Arg Lys Ser Ser Ile 
                405                 410                 415     


Ser Ser Ile Ser Gly Arg Asp Asp Leu Met Asp Tyr His Arg Arg Gln 
            420                 425                 430         


Arg Glu Glu Arg Leu Arg Glu Gln Glu Met Glu Arg Leu Glu Arg Gln 
        435                 440                 445             


Arg Leu Glu Thr Ile Leu Ser Leu Cys Ala Glu Tyr Thr Lys Pro Asp 
    450                 455                 460                 


Ser Arg Leu Ser Thr Gly Thr Thr Val Glu Asp Val Gln Lys Ile Asn 
465                 470                 475                 480 


Lys Glu Leu Glu Lys Leu Gln Leu Ser Asp Glu Glu Ser Val Phe Glu 
                485                 490                 495     


Glu Ala Leu Met Ser Pro Asp Thr Arg Tyr Arg Cys His Arg Lys Asp 
            500                 505                 510         


Ser Leu Pro Asp Ala Asp Leu Ala Ser Cys Gly Ser Leu Ser Gln Ser 
        515                 520                 525             


Ser Ala Ser Phe Phe Thr Pro Arg Ser Thr Arg Asn Asp Glu Leu Leu 
    530                 535                 540                 


Ser Asp Leu Thr Arg Thr Pro Pro Pro Pro Ser Ser Thr Phe Pro Lys 
545                 550                 555                 560 


Ala Ser Ser Glu Ser Ser Tyr Leu Ser Ile Leu Pro Lys Thr Pro Glu 
                565                 570                 575     


Gly Ile Ser Glu Glu Gln Arg Ser Gln Glu Leu Ala Ala Met Glu Glu 
            580                 585                 590         


Thr Arg Ile Val Ile Leu Asn Asn Leu Glu Glu Leu Lys Gln Lys Ile 
        595                 600                 605             


Lys Asp Ile Asn Asp Gln Met Asp Glu Ser Phe Arg Glu Leu Asp Met 
    610                 615                 620                 


Glu Cys Ala Leu Leu Asp Gly Glu Gln Lys Ser Glu Thr Thr Glu Leu 
625                 630                 635                 640 


Met Lys Glu Lys Glu Ile Leu Asp His Leu Asn Arg Lys Ile Ala Glu 
                645                 650                 655     


Leu Glu Lys Asn Ile Val Gly Glu Lys Thr Lys Asp Ala Asp Leu Leu 
            660                 665                 670         


Asp Val Glu Ser Lys His Phe Glu Asp Leu Glu Phe Gln Gln Leu Glu 
        675                 680                 685             


His Glu Ser Arg Leu Asp Glu Glu Lys Glu Asn Leu Thr Gln Gln Leu 
    690                 695                 700                 


Leu Arg Glu Val Ala Glu Tyr Gln Arg Asn Ile Val Ser Arg Lys Glu 
705                 710                 715                 720 


Lys Ile Ser Ala Leu Lys Lys Gln Ala Asn His Ile Val Gln Gln Ala 
                725                 730                 735     


Gln Arg Glu Gln Asp His Phe Val Lys Glu Lys Asn Asn Leu Ile Met 
            740                 745                 750         


Met Leu Gln Arg Glu Lys Glu Asn Leu Cys Asn Leu Glu Lys Lys Tyr 
        755                 760                 765             


Ser Ser Leu Ser Gly Gly Lys Gly Phe Pro Val Asn Pro Asn Thr Leu 
    770                 775                 780                 


Lys Glu Gly Tyr Ile Ser Val Asn Glu Ile Asn Glu Pro Cys Gly Asn 
785                 790                 795                 800 


Ser Thr Asn Leu Ser Pro Ser Thr Gln Phe Pro Ala Asp Ala Asp Ala 
                805                 810                 815     


Val Ala Thr Glu Pro Ala Thr Ala Val Leu Ala Ser Gln Pro Gln Ser 
            820                 825                 830         


Lys Glu His Phe Arg Ser Leu Glu Glu Arg Lys Lys Gln His Lys Glu 
        835                 840                 845             


Gly Leu Tyr Leu Ser Asp Thr Leu Pro Arg Lys Lys Thr Thr Ser Ser 
    850                 855                 860                 


Ile Ser Pro His Phe Ser Ser Ala Thr Met Gly Arg Ser Ile Thr Pro 
865                 870                 875                 880 


Lys Ala His Leu Pro Leu Gly Gln Ser Asn Ser Cys Gly Ser Val Leu 
                885                 890                 895     


Pro Pro Ser Leu Ala Ala Met Ala Lys Asp Ser Glu Ser Arg Arg Met 
            900                 905                 910         


Leu Arg Gly Tyr Asn His Gln Gln Met Ser Glu Gly His Arg Gln Lys 
        915                 920                 925             


Ser Glu Phe Tyr Asn Arg Thr Ala Ser Glu Ser Asn Val Tyr Leu Asn 
    930                 935                 940                 


Ser Phe His Tyr Pro Asp His Ser Tyr Lys Asp Gln Ala Phe Asp Thr 
945                 950                 955                 960 


Leu Ser Leu Asp Ser Ser Asp Ser Met Glu Thr Ser Ile Ser Ala Cys 
                965                 970                 975     


Ser Pro Asp Asn Ile Ser Ser Ala Ser Thr Ser Asn Ile Ala Arg Ile 
            980                 985                 990         


Glu Glu Met Glu Arg Leu Leu Lys  Gln Ala His Ala Glu  Lys Thr Arg 
        995                 1000                 1005             


Leu Leu  Glu Ser Arg Glu Arg  Glu Met Glu Ala Lys  Lys Arg Ala 
    1010                 1015                 1020             


Leu Glu  Glu Glu Lys Arg Arg  Arg Glu Ile Leu Glu  Lys Arg Leu 
    1025                 1030                 1035             


Gln Glu  Glu Thr Ser Gln Arg  Gln Lys Leu Ile Glu  Lys Glu Val 
    1040                 1045                 1050             


Lys Ile  Arg Glu Arg Gln Arg  Ala Gln Ala Arg Pro  Leu Thr Arg 
    1055                 1060                 1065             


Tyr Leu  Pro Val Arg Lys Glu  Asp Phe Asp Leu Arg  Ser His Val 
    1070                 1075                 1080             


Glu Thr  Ala Gly His Asn Ile  Asp Thr Cys Tyr His  Val Ser Ile 
    1085                 1090                 1095             


Thr Glu  Lys Thr Cys Arg Gly  Phe Leu Ile Lys Met  Gly Gly Lys 
    1100                 1105                 1110             


Ile Lys  Thr Trp Lys Lys Arg  Trp Phe Val Phe Asp  Arg Asn Lys 
    1115                 1120                 1125             


Arg Thr  Phe Ser Tyr Tyr Ala  Asp Lys His Glu Thr  Lys Leu Lys 
    1130                 1135                 1140             


Gly Val  Ile Tyr Phe Gln Ala  Ile Glu Glu Val Tyr  Tyr Asp His 
    1145                 1150                 1155             


Leu Lys  Asn Ala Asn Lys Ser  Pro Asn Pro Leu Leu  Thr Phe Ser 
    1160                 1165                 1170             


Val Lys  Thr His Asp Arg Ile  Tyr Tyr Met Val Ala  Pro Ser Pro 
    1175                 1180                 1185             


Glu Ala  Met Arg Ile Trp Met  Asp Val Ile Val Thr  Gly Ala Glu 
    1190                 1195                 1200             


Gly Tyr  Thr His Phe Leu Leu  
    1205                 1210 


<210>  3492
<211>  304
<212>  PRT
<213>  homo sapiens

<400>  3492

Met Leu Ala Val Arg Lys Ala Arg Arg Lys Leu Arg Met Gly Thr Ile 
1               5                   10                  15      


Cys Ser Pro Asn Pro Ser Gly Thr Lys Thr Ser Ser Glu Val Cys Asn 
            20                  25                  30          


Ala Asp Trp Met Ala Ser Leu Pro Pro His Leu His Asn Leu Pro Leu 
        35                  40                  45              


Ser Asn Leu Ala Ile Pro Gly Ser His Asp Ser Phe Ser Tyr Trp Val 
    50                  55                  60                  


Asp Glu Lys Ser Pro Val Gly Pro Asp Gln Thr Gln Ala Ile Lys Arg 
65                  70                  75                  80  


Leu Ala Arg Ile Ser Leu Val Lys Lys Leu Met Lys Lys Trp Ser Val 
                85                  90                  95      


Thr Gln Asn Leu Thr Phe Arg Glu Gln Leu Glu Ala Gly Ile Arg Tyr 
            100                 105                 110         


Phe Asp Leu Arg Val Ser Ser Lys Pro Gly Asp Ala Asp Gln Glu Ile 
        115                 120                 125             


Tyr Phe Ile His Gly Leu Phe Gly Ile Lys Val Trp Asp Gly Leu Met 
    130                 135                 140                 


Glu Ile Asp Ser Phe Leu Thr Gln His Pro Gln Glu Ile Ile Phe Leu 
145                 150                 155                 160 


Asp Phe Asn His Phe Tyr Ala Met Asp Glu Thr His His Lys Cys Leu 
                165                 170                 175     


Val Leu Arg Ile Gln Glu Ala Phe Gly Asn Lys Leu Cys Pro Ala Cys 
            180                 185                 190         


Ser Val Glu Ser Leu Thr Leu Arg Thr Leu Trp Glu Lys Asn Cys Gln 
        195                 200                 205             


Val Leu Ile Phe Tyr His Cys Pro Phe Tyr Lys Gln Tyr Pro Phe Leu 
    210                 215                 220                 


Trp Pro Gly Lys Lys Ile Pro Ala Pro Trp Ala Asn Thr Thr Ser Val 
225                 230                 235                 240 


Arg Lys Leu Ile Leu Phe Leu Glu Thr Thr Leu Ser Glu Arg Ala Ser 
                245                 250                 255     


Arg Gly Ser Phe His Val Ser Gln Ala Ile Leu Thr Pro Arg Val Lys 
            260                 265                 270         


Thr Ile Ala Arg Gly Leu Val Gly Gly Leu Lys Asn Thr Leu Val His 
        275                 280                 285             


Arg Leu Ala Leu Ile Pro Val Tyr Pro Leu Arg Phe Ser Arg Arg Ser 
    290                 295                 300                 


<210>  3493
<211>  460
<212>  PRT
<213>  homo sapiens

<400>  3493

Met His Ser Pro Pro Arg Asp Gln Ala Ala Ile Met Leu Trp Lys Leu 
1               5                   10                  15      


Val Glu Asn Val Lys Tyr Glu Asp Ile Tyr Glu Asp Arg His Asp Gly 
            20                  25                  30          


Val Pro Ser His Ser Ser Arg Leu Ser Gln Leu Gly Ser Val Ser Gln 
        35                  40                  45              


Gly Pro Tyr Ser Ser Ala Pro Pro Leu Ser His Thr Pro Ser Ser Asp 
    50                  55                  60                  


Phe Gln Pro Pro Tyr Phe Pro Pro Pro Tyr Gln Pro Leu Pro Tyr His 
65                  70                  75                  80  


Gln Ser Gln Asp Pro Tyr Ser His Val Asn Asp Pro Tyr Ser Leu Asn 
                85                  90                  95      


Pro Leu His Gln Pro Gln Gln His Pro Trp Gly Gln Arg Gln Arg Gln 
            100                 105                 110         


Glu Val Gly Ser Glu Ala Gly Ser Leu Leu Pro Gln Pro Arg Ala Ala 
        115                 120                 125             


Leu Pro Gln Leu Ser Gly Leu Asp Pro Arg Arg Asp Tyr His Ser Val 
    130                 135                 140                 


Arg Arg Pro Asp Val Leu Leu His Ser Ala His His Gly Leu Asp Ala 
145                 150                 155                 160 


Gly Met Gly Asp Ser Leu Ser Leu His Gly Leu Gly His Pro Gly Met 
                165                 170                 175     


Glu Asp Val Gln Ser Val Glu Asp Ala Asn Asn Ser Gly Met Asn Leu 
            180                 185                 190         


Leu Asp Gln Ser Val Ile Lys Lys Val Pro Val Pro Pro Lys Ser Val 
        195                 200                 205             


Thr Ser Leu Met Met Asn Lys Asp Gly Phe Leu Gly Gly Met Ser Val 
    210                 215                 220                 


Asn Thr Gly Glu Val Phe Cys Ser Val Pro Gly Arg Leu Ser Leu Leu 
225                 230                 235                 240 


Ser Ser Thr Ser Lys Tyr Lys Val Thr Val Gly Glu Val Gln Arg Arg 
                245                 250                 255     


Leu Ser Pro Pro Glu Cys Leu Asn Ala Ser Leu Leu Gly Gly Val Leu 
            260                 265                 270         


Arg Arg Ala Lys Ser Lys Asn Gly Gly Arg Ser Leu Arg Glu Arg Leu 
        275                 280                 285             


Glu Lys Ile Gly Leu Asn Leu Pro Ala Gly Arg Arg Lys Ala Ala Asn 
    290                 295                 300                 


Val Thr Leu Leu Thr Ser Leu Val Glu Gly Glu Ala Val His Leu Ala 
305                 310                 315                 320 


Arg Asp Phe Gly Tyr Ile Cys Glu Thr Glu Phe Pro Ala Lys Ala Val 
                325                 330                 335     


Ser Glu Tyr Leu Asn Arg Gln His Thr Asp Pro Ser Asp Leu His Ser 
            340                 345                 350         


Arg Lys Asn Met Leu Leu Ala Thr Lys Gln Leu Cys Lys Glu Phe Thr 
        355                 360                 365             


Asp Leu Leu Ala Gln Asp Arg Thr Pro Ile Gly Asn Ser Arg Pro Ser 
    370                 375                 380                 


Pro Ile Leu Glu Pro Gly Ile Gln Ser Cys Leu Thr His Phe Ser Leu 
385                 390                 395                 400 


Ile Thr His Gly Phe Gly Ala Pro Ala Ile Cys Ala Ala Leu Thr Ala 
                405                 410                 415     


Leu Gln Asn Tyr Leu Thr Glu Ala Leu Lys Gly Met Asp Lys Met Phe 
            420                 425                 430         


Leu Asn Asn Thr Thr Thr Asn Arg His Thr Ser Gly Glu Gly Pro Gly 
        435                 440                 445             


Ser Lys Thr Gly Asp Lys Glu Glu Lys His Arg Lys 
    450                 455                 460 


<210>  3494
<211>  338
<212>  PRT
<213>  homo sapiens

<400>  3494

Met Glu Tyr Phe Met Val Pro Thr Gln Lys Val Pro Ser Leu Gln His 
1               5                   10                  15      


Phe Arg Lys Thr Glu Lys Glu Val Ile Gly Gly Leu Cys Ser Leu Ala 
            20                  25                  30          


Asn Ile Pro Leu Thr Pro Glu Thr Gln Arg Asp Gln Glu Arg Arg Ile 
        35                  40                  45              


Arg Arg Glu Ile Ala Asn Ser Asn Glu Arg Arg Arg Met Gln Ser Ile 
    50                  55                  60                  


Asn Ala Gly Phe Gln Ser Leu Lys Thr Leu Ile Pro His Thr Asp Gly 
65                  70                  75                  80  


Glu Lys Leu Ser Lys Ala Ala Ile Leu Gln Gln Thr Ala Glu Tyr Ile 
                85                  90                  95      


Phe Ser Leu Glu Gln Glu Lys Thr Arg Leu Leu Gln Gln Asn Thr Gln 
            100                 105                 110         


Leu Lys Arg Phe Ile Gln Glu Leu Ser Gly Ser Ser Pro Lys Arg Arg 
        115                 120                 125             


Arg Ala Glu Asp Lys Asp Glu Gly Ile Gly Ser Pro Asp Ile Trp Glu 
    130                 135                 140                 


Asp Glu Lys Ala Glu Asp Leu Arg Arg Glu Met Ile Glu Leu Arg Gln 
145                 150                 155                 160 


Gln Leu Asp Lys Glu Arg Ser Val Arg Met Met Leu Glu Glu Gln Val 
                165                 170                 175     


Arg Ser Leu Glu Ala His Met Tyr Pro Glu Lys Leu Lys Val Ile Ala 
            180                 185                 190         


Gln Gln Val Gln Leu Gln Gln Gln Gln Glu Gln Val Arg Leu Leu His 
        195                 200                 205             


Gln Glu Lys Leu Glu Arg Glu Gln Gln Gln Leu Arg Thr Gln Leu Leu 
    210                 215                 220                 


Pro Pro Pro Ala Pro Thr His His Pro Thr Val Ile Val Pro Ala Pro 
225                 230                 235                 240 


Pro Pro Pro Pro Ser His His Ile Asn Val Val Thr Met Gly Pro Ser 
                245                 250                 255     


Ser Val Ile Asn Ser Val Ser Thr Ser Arg Gln Asn Leu Asp Thr Ile 
            260                 265                 270         


Val Gln Ala Ile Gln His Ile Glu Gly Thr Gln Glu Lys Gln Glu Leu 
        275                 280                 285             


Glu Glu Glu Gln Arg Arg Ala Val Ile Val Lys Pro Val Arg Ser Cys 
    290                 295                 300                 


Pro Glu Ala Pro Thr Ser Asp Thr Ala Ser Asp Ser Glu Ala Ser Asp 
305                 310                 315                 320 


Ser Asp Ala Met Asp Gln Ser Arg Glu Glu Pro Ser Gly Asp Gly Glu 
                325                 330                 335     


Leu Pro 
        


<210>  3495
<211>  769
<212>  PRT
<213>  homo sapiens

<400>  3495

Met Cys Gly Ser Ala Leu Ala Phe Phe Thr Ala Ala Phe Val Cys Leu 
1               5                   10                  15      


Gln Asn Asp Arg Arg Gly Pro Ala Ser Phe Leu Trp Ala Ala Trp Val 
            20                  25                  30          


Phe Ser Leu Val Leu Gly Leu Gly Gln Gly Glu Asp Asn Arg Cys Ala 
        35                  40                  45              


Ser Ser Asn Ala Ala Ser Cys Ala Arg Cys Leu Ala Leu Gly Pro Glu 
    50                  55                  60                  


Cys Gly Trp Cys Val Gln Glu Asp Phe Ile Ser Gly Gly Ser Arg Ser 
65                  70                  75                  80  


Glu Arg Cys Asp Ile Val Ser Asn Leu Ile Ser Lys Gly Cys Ser Val 
                85                  90                  95      


Asp Ser Ile Glu Tyr Pro Ser Val His Val Ile Ile Pro Thr Glu Asn 
            100                 105                 110         


Glu Ile Asn Thr Gln Val Thr Pro Gly Glu Val Ser Ile Gln Leu Arg 
        115                 120                 125             


Pro Gly Ala Glu Ala Asn Phe Met Leu Lys Val His Pro Leu Lys Lys 
    130                 135                 140                 


Tyr Pro Val Asp Leu Tyr Tyr Leu Val Asp Val Ser Ala Ser Met His 
145                 150                 155                 160 


Asn Asn Ile Glu Lys Leu Asn Ser Val Gly Asn Asp Leu Ser Arg Lys 
                165                 170                 175     


Met Ala Phe Phe Ser Arg Asp Phe Arg Leu Gly Phe Gly Ser Tyr Val 
            180                 185                 190         


Asp Lys Thr Val Ser Pro Tyr Ile Ser Ile His Pro Glu Arg Ile His 
        195                 200                 205             


Asn Gln Cys Ser Asp Tyr Asn Leu Asp Cys Met Pro Pro His Gly Tyr 
    210                 215                 220                 


Ile His Val Leu Ser Leu Thr Glu Asn Ile Thr Glu Phe Glu Lys Ala 
225                 230                 235                 240 


Val His Arg Gln Lys Ile Ser Gly Asn Ile Asp Thr Pro Glu Gly Gly 
                245                 250                 255     


Phe Asp Ala Met Leu Gln Ala Ala Val Cys Glu Ser His Ile Gly Trp 
            260                 265                 270         


Arg Lys Glu Ala Lys Arg Leu Leu Leu Val Met Thr Asp Gln Thr Ser 
        275                 280                 285             


His Leu Ala Leu Asp Ser Lys Leu Ala Gly Ile Val Val Pro Asn Asp 
    290                 295                 300                 


Gly Asn Cys His Leu Lys Asn Asn Val Tyr Val Lys Ser Thr Thr Met 
305                 310                 315                 320 


Glu His Pro Ser Leu Gly Gln Leu Ser Glu Lys Leu Ile Asp Asn Asn 
                325                 330                 335     


Ile Asn Val Ile Phe Ala Val Gln Gly Lys Gln Phe His Trp Tyr Lys 
            340                 345                 350         


Asp Leu Leu Pro Leu Leu Pro Gly Thr Ile Ala Gly Glu Ile Glu Ser 
        355                 360                 365             


Lys Ala Ala Asn Leu Asn Asn Leu Val Val Glu Ala Tyr Gln Lys Leu 
    370                 375                 380                 


Ile Ser Glu Val Lys Val Gln Val Glu Asn Gln Val Gln Gly Ile Tyr 
385                 390                 395                 400 


Phe Asn Ile Thr Ala Ile Cys Pro Asp Gly Ser Arg Lys Pro Gly Met 
                405                 410                 415     


Glu Gly Cys Arg Asn Val Thr Ser Asn Asp Glu Val Leu Phe Asn Val 
            420                 425                 430         


Thr Val Thr Met Lys Lys Cys Asp Val Thr Gly Gly Lys Asn Tyr Ala 
        435                 440                 445             


Ile Ile Lys Pro Ile Gly Phe Asn Glu Thr Ala Lys Ile His Ile His 
    450                 455                 460                 


Arg Asn Cys Ser Cys Gln Cys Glu Asp Asn Arg Gly Pro Lys Gly Lys 
465                 470                 475                 480 


Cys Val Asp Glu Thr Phe Leu Asp Ser Lys Cys Phe Gln Cys Asp Glu 
                485                 490                 495     


Asn Lys Cys His Phe Asp Glu Asp Gln Phe Ser Ser Glu Ser Cys Lys 
            500                 505                 510         


Ser His Lys Asp Gln Pro Val Cys Ser Gly Arg Gly Val Cys Val Cys 
        515                 520                 525             


Gly Lys Cys Ser Cys His Lys Ile Lys Leu Gly Lys Val Tyr Gly Lys 
    530                 535                 540                 


Tyr Cys Glu Lys Asp Asp Phe Ser Cys Pro Tyr His His Gly Asn Leu 
545                 550                 555                 560 


Cys Ala Gly His Gly Glu Cys Glu Ala Gly Arg Cys Gln Cys Phe Ser 
                565                 570                 575     


Gly Trp Glu Gly Asp Arg Cys Gln Cys Pro Ser Ala Ala Ala Gln His 
            580                 585                 590         


Cys Val Asn Ser Lys Gly Gln Val Cys Ser Gly Arg Gly Thr Cys Val 
        595                 600                 605             


Cys Gly Arg Cys Glu Cys Thr Asp Pro Arg Ser Ile Gly Arg Phe Cys 
    610                 615                 620                 


Glu His Cys Pro Thr Cys Tyr Thr Ala Cys Lys Glu Asn Trp Asn Cys 
625                 630                 635                 640 


Met Gln Cys Leu His Pro His Asn Leu Ser Gln Ala Ile Leu Asp Gln 
                645                 650                 655     


Cys Lys Thr Ser Cys Ala Leu Met Glu Gln Gln His Tyr Val Asp Gln 
            660                 665                 670         


Thr Ser Glu Cys Phe Ser Ser Pro Ser Tyr Leu Arg Ile Phe Phe Ile 
        675                 680                 685             


Ile Phe Ile Val Thr Phe Leu Ile Gly Leu Leu Lys Val Leu Ile Ile 
    690                 695                 700                 


Arg Gln Val Ile Leu Gln Trp Asn Ser Asn Lys Ile Lys Ser Ser Ser 
705                 710                 715                 720 


Asp Tyr Arg Val Ser Ala Ser Lys Lys Asp Lys Leu Ile Leu Gln Ser 
                725                 730                 735     


Val Cys Thr Arg Ala Val Thr Tyr Arg Arg Glu Lys Pro Glu Glu Ile 
            740                 745                 750         


Lys Met Asp Ile Ser Lys Leu Asn Ala His Glu Thr Phe Arg Cys Asn 
        755                 760                 765             


Phe 
    


<210>  3496
<211>  163
<212>  PRT
<213>  homo sapiens

<400>  3496

Met Met Pro Gly Gln Ile Pro Asp Pro Ser Val Thr Thr Gly Ser Leu 
1               5                   10                  15      


Pro Gly Leu Gly Pro Leu Thr Gly Leu Pro Ser Ser Ala Leu Thr Val 
            20                  25                  30          


Glu Glu Leu Lys Tyr Ala Asp Ile Arg Asn Leu Gly Ala Met Ile Ala 
        35                  40                  45              


Pro Leu His Phe Leu Glu Val Lys Leu Gly Lys Arg Pro Gln Pro Val 
    50                  55                  60                  


Lys Ser Glu Leu Asp Glu Glu Glu Glu Arg Arg Lys Arg Arg Arg Glu 
65                  70                  75                  80  


Lys Asn Lys Val Ala Ala Ala Arg Cys Arg Asn Lys Lys Lys Glu Arg 
                85                  90                  95      


Thr Glu Phe Leu Gln Arg Glu Ser Glu Arg Leu Glu Leu Met Asn Ala 
            100                 105                 110         


Glu Leu Lys Thr Gln Ile Glu Glu Leu Lys Gln Glu Arg Gln Gln Leu 
        115                 120                 125             


Ile Leu Met Leu Asn Arg His Arg Pro Thr Cys Ile Val Arg Thr Asp 
    130                 135                 140                 


Ser Val Lys Thr Pro Glu Ser Glu Gly Asn Pro Leu Leu Glu Gln Leu 
145                 150                 155                 160 


Glu Lys Lys 
            


<210>  3497
<211>  163
<212>  PRT
<213>  homo sapiens

<400>  3497

Met Met Pro Gly Gln Ile Pro Asp Pro Ser Val Thr Thr Gly Ser Leu 
1               5                   10                  15      


Pro Gly Leu Gly Pro Leu Thr Gly Leu Pro Ser Ser Ala Leu Thr Val 
            20                  25                  30          


Glu Glu Leu Lys Tyr Ala Asp Ile Arg Asn Leu Gly Ala Met Ile Ala 
        35                  40                  45              


Pro Leu His Phe Leu Glu Val Lys Leu Gly Lys Arg Pro Gln Pro Val 
    50                  55                  60                  


Lys Ser Glu Leu Asp Glu Glu Glu Glu Arg Arg Lys Arg Arg Arg Glu 
65                  70                  75                  80  


Lys Asn Lys Val Ala Ala Ala Arg Cys Arg Asn Lys Lys Lys Glu Arg 
                85                  90                  95      


Thr Glu Phe Leu Gln Arg Glu Ser Glu Arg Leu Glu Leu Met Asn Ala 
            100                 105                 110         


Glu Leu Lys Thr Gln Ile Glu Glu Leu Lys Gln Glu Arg Gln Gln Leu 
        115                 120                 125             


Ile Leu Met Leu Asn Arg His Arg Pro Thr Cys Ile Val Arg Thr Asp 
    130                 135                 140                 


Ser Val Lys Thr Pro Glu Ser Glu Gly Asn Pro Leu Leu Glu Gln Leu 
145                 150                 155                 160 


Glu Lys Lys 
            


<210>  3498
<211>  174
<212>  PRT
<213>  homo sapiens

<400>  3498

Met Val Ala Gly Trp Pro Ala Thr Pro Pro Ala Met Met Pro Gly Gln 
1               5                   10                  15      


Ile Pro Asp Pro Ser Val Thr Thr Gly Ser Leu Pro Gly Leu Gly Pro 
            20                  25                  30          


Leu Thr Gly Leu Pro Ser Ser Ala Leu Thr Val Glu Glu Leu Lys Tyr 
        35                  40                  45              


Ala Asp Ile Arg Asn Leu Gly Ala Met Ile Ala Pro Leu His Phe Leu 
    50                  55                  60                  


Glu Val Lys Leu Gly Lys Arg Pro Gln Pro Val Lys Ser Glu Leu Asp 
65                  70                  75                  80  


Glu Glu Glu Glu Arg Arg Lys Arg Arg Arg Glu Lys Asn Lys Val Ala 
                85                  90                  95      


Ala Ala Arg Cys Arg Asn Lys Lys Lys Glu Arg Thr Glu Phe Leu Gln 
            100                 105                 110         


Arg Glu Ser Glu Arg Leu Glu Leu Met Asn Ala Glu Leu Lys Thr Gln 
        115                 120                 125             


Ile Glu Glu Leu Lys Gln Glu Arg Gln Gln Leu Ile Leu Met Leu Asn 
    130                 135                 140                 


Arg His Arg Pro Thr Cys Ile Val Arg Thr Asp Ser Val Lys Thr Pro 
145                 150                 155                 160 


Glu Ser Glu Gly Asn Pro Leu Leu Glu Gln Leu Glu Lys Lys 
                165                 170                 


<210>  3499
<211>  846
<212>  PRT
<213>  homo sapiens

<400>  3499

Met Leu Phe Thr Val Ser Cys Ser Lys Met Ser Ser Ile Val Asp Arg 
1               5                   10                  15      


Asp Asp Ser Ser Ile Phe Asp Gly Leu Val Glu Glu Asp Asp Lys Asp 
            20                  25                  30          


Lys Ala Lys Arg Val Ser Arg Asn Lys Ser Glu Lys Lys Arg Arg Asp 
        35                  40                  45              


Gln Phe Asn Val Leu Ile Lys Glu Leu Gly Ser Met Leu Pro Gly Asn 
    50                  55                  60                  


Ala Arg Lys Met Asp Lys Ser Thr Val Leu Gln Lys Ser Ile Asp Phe 
65                  70                  75                  80  


Leu Arg Lys His Lys Glu Ile Thr Ala Gln Ser Asp Ala Ser Glu Ile 
                85                  90                  95      


Arg Gln Asp Trp Lys Pro Thr Phe Leu Ser Asn Glu Glu Phe Thr Gln 
            100                 105                 110         


Leu Met Leu Glu Ala Leu Asp Gly Phe Phe Leu Ala Ile Met Thr Asp 
        115                 120                 125             


Gly Ser Ile Ile Tyr Val Ser Glu Ser Val Thr Ser Leu Leu Glu His 
    130                 135                 140                 


Leu Pro Ser Asp Leu Val Asp Gln Ser Ile Phe Asn Phe Ile Pro Glu 
145                 150                 155                 160 


Gly Glu His Ser Glu Val Tyr Lys Ile Leu Ser Thr His Leu Leu Glu 
                165                 170                 175     


Ser Asp Ser Leu Thr Pro Glu Tyr Leu Lys Ser Lys Asn Gln Leu Glu 
            180                 185                 190         


Phe Cys Cys His Met Leu Arg Gly Thr Ile Asp Pro Lys Glu Pro Ser 
        195                 200                 205             


Thr Tyr Glu Tyr Val Lys Phe Ile Gly Asn Phe Lys Ser Leu Asn Ser 
    210                 215                 220                 


Val Ser Ser Ser Ala His Asn Gly Phe Glu Gly Thr Ile Gln Arg Thr 
225                 230                 235                 240 


His Arg Pro Ser Tyr Glu Asp Arg Val Cys Phe Val Ala Thr Val Arg 
                245                 250                 255     


Leu Ala Thr Pro Gln Phe Ile Lys Glu Met Cys Thr Val Glu Glu Pro 
            260                 265                 270         


Asn Glu Glu Phe Thr Ser Arg His Ser Leu Glu Trp Lys Phe Leu Phe 
        275                 280                 285             


Leu Asp His Arg Ala Pro Pro Ile Ile Gly Tyr Leu Pro Phe Glu Val 
    290                 295                 300                 


Leu Gly Thr Ser Gly Tyr Asp Tyr Tyr His Val Asp Asp Leu Glu Asn 
305                 310                 315                 320 


Leu Ala Lys Cys His Glu His Leu Met Gln Tyr Gly Lys Gly Lys Ser 
                325                 330                 335     


Cys Tyr Tyr Arg Phe Leu Thr Lys Gly Gln Gln Trp Ile Trp Leu Gln 
            340                 345                 350         


Thr His Tyr Tyr Ile Thr Tyr His Gln Trp Asn Ser Arg Pro Glu Phe 
        355                 360                 365             


Ile Val Cys Thr His Thr Val Val Ser Tyr Ala Glu Val Arg Ala Glu 
    370                 375                 380                 


Arg Arg Arg Glu Leu Gly Ile Glu Glu Ser Leu Pro Glu Thr Ala Ala 
385                 390                 395                 400 


Asp Lys Ser Gln Asp Ser Gly Ser Asp Asn Arg Ile Asn Thr Val Ser 
                405                 410                 415     


Leu Lys Glu Ala Leu Glu Arg Phe Asp His Ser Pro Thr Pro Ser Ala 
            420                 425                 430         


Ser Ser Arg Ser Ser Arg Lys Ser Ser His Thr Ala Val Ser Asp Pro 
        435                 440                 445             


Ser Ser Thr Pro Thr Lys Ile Pro Thr Asp Thr Ser Thr Pro Pro Arg 
    450                 455                 460                 


Gln His Leu Pro Ala His Glu Lys Met Val Gln Arg Arg Ser Ser Phe 
465                 470                 475                 480 


Ser Ser Gln Ser Ile Asn Ser Gln Ser Val Gly Ser Ser Leu Thr Gln 
                485                 490                 495     


Pro Val Met Ser Gln Ala Thr Asn Leu Pro Ile Pro Gln Gly Met Ser 
            500                 505                 510         


Gln Phe Gln Phe Ser Ala Gln Leu Gly Ala Met Gln His Leu Lys Asp 
        515                 520                 525             


Gln Leu Glu Gln Arg Thr Arg Met Ile Glu Ala Asn Ile His Arg Gln 
    530                 535                 540                 


Gln Glu Glu Leu Arg Lys Ile Gln Glu Gln Leu Gln Met Val His Gly 
545                 550                 555                 560 


Gln Gly Leu Gln Met Phe Leu Gln Gln Ser Asn Pro Gly Leu Asn Phe 
                565                 570                 575     


Gly Ser Val Gln Leu Ser Ser Gly Asn Ser Ser Asn Ile Gln Gln Leu 
            580                 585                 590         


Ala Pro Ile Asn Met Gln Gly Gln Val Val Pro Thr Asn Gln Ile Gln 
        595                 600                 605             


Ser Gly Met Asn Thr Gly His Ile Gly Thr Thr Gln His Met Ile Gln 
    610                 615                 620                 


Gln Gln Thr Leu Gln Ser Thr Ser Thr Gln Ser Gln Gln Asn Val Leu 
625                 630                 635                 640 


Ser Gly His Ser Gln Gln Thr Ser Leu Pro Ser Gln Thr Gln Ser Thr 
                645                 650                 655     


Leu Thr Ala Pro Leu Tyr Asn Thr Met Val Ile Ser Gln Pro Ala Ala 
            660                 665                 670         


Gly Ser Met Val Gln Ile Pro Ser Ser Met Pro Gln Asn Ser Thr Gln 
        675                 680                 685             


Ser Ala Ala Val Thr Thr Phe Thr Gln Asp Arg Gln Ile Arg Phe Ser 
    690                 695                 700                 


Gln Gly Gln Gln Leu Val Thr Lys Leu Val Thr Ala Pro Val Ala Cys 
705                 710                 715                 720 


Gly Ala Val Met Val Pro Ser Thr Met Leu Met Gly Gln Val Val Thr 
                725                 730                 735     


Ala Tyr Pro Thr Phe Ala Thr Gln Gln Gln Gln Ser Gln Thr Leu Ser 
            740                 745                 750         


Val Thr Gln Gln Gln Gln Gln Gln Ser Ser Gln Glu Gln Gln Leu Thr 
        755                 760                 765             


Ser Val Gln Gln Pro Ser Gln Ala Gln Leu Thr Gln Pro Pro Gln Gln 
    770                 775                 780                 


Phe Leu Gln Thr Ser Arg Leu Leu His Gly Asn Pro Ser Thr Gln Leu 
785                 790                 795                 800 


Ile Leu Ser Ala Ala Phe Pro Leu Gln Gln Ser Thr Phe Pro Gln Ser 
                805                 810                 815     


His His Gln Gln His Gln Ser Gln Gln Gln Gln Gln Leu Ser Arg His 
            820                 825                 830         


Arg Thr Asp Ser Leu Pro Asp Pro Ser Lys Val Gln Pro Gln 
        835                 840                 845     


<210>  3500
<211>  756
<212>  PRT
<213>  homo sapiens

<400>  3500

Met Leu Gly Ile Cys Arg Gly Arg Arg Lys Phe Leu Ala Ala Ser Leu 
1               5                   10                  15      


Ser Leu Leu Cys Ile Pro Ala Ile Thr Trp Ile Tyr Leu Phe Ser Gly 
            20                  25                  30          


Ser Phe Glu Asp Gly Lys Pro Val Ser Leu Ser Pro Leu Glu Ser Gln 
        35                  40                  45              


Ala His Ser Pro Arg Tyr Thr Ala Ser Ser Gln Arg Glu Arg Glu Ser 
    50                  55                  60                  


Leu Glu Val Arg Met Arg Glu Val Glu Glu Glu Asn Arg Ala Leu Arg 
65                  70                  75                  80  


Arg Gln Leu Ser Leu Ala Gln Gly Arg Ala Pro Ser His Arg Arg Gly 
                85                  90                  95      


Asn His Ser Lys Thr Tyr Ser Met Glu Glu Gly Thr Gly Asp Ser Glu 
            100                 105                 110         


Asn Leu Arg Ala Gly Ile Val Ala Gly Asn Ser Ser Glu Cys Gly Gln 
        115                 120                 125             


Gln Pro Val Val Glu Lys Cys Glu Thr Ile His Val Ala Ile Val Cys 
    130                 135                 140                 


Ala Gly Tyr Asn Ala Ser Arg Asp Val Val Thr Leu Val Lys Ser Val 
145                 150                 155                 160 


Leu Phe His Arg Arg Asn Pro Leu His Phe His Leu Ile Ala Asp Ser 
                165                 170                 175     


Ile Ala Glu Gln Ile Leu Ala Thr Leu Phe Gln Thr Trp Met Val Pro 
            180                 185                 190         


Ala Val Arg Val Asp Phe Tyr Asn Ala Asp Glu Leu Lys Ser Glu Val 
        195                 200                 205             


Ser Trp Ile Pro Asn Lys His Tyr Ser Gly Ile Tyr Gly Leu Met Lys 
    210                 215                 220                 


Leu Val Leu Thr Lys Thr Leu Pro Ala Asn Leu Glu Arg Val Ile Val 
225                 230                 235                 240 


Leu Asp Thr Asp Ile Thr Phe Ala Thr Asp Ile Ala Glu Leu Trp Ala 
                245                 250                 255     


Val Phe His Lys Phe Lys Gly Gln Gln Val Leu Gly Leu Val Glu Asn 
            260                 265                 270         


Gln Ser Asp Trp Tyr Leu Gly Asn Leu Trp Lys Asn His Arg Pro Trp 
        275                 280                 285             


Pro Ala Leu Gly Arg Gly Tyr Asn Thr Gly Val Ile Leu Leu Leu Leu 
    290                 295                 300                 


Asp Lys Leu Arg Lys Met Lys Trp Glu Gln Met Trp Arg Leu Thr Ala 
305                 310                 315                 320 


Glu Arg Glu Leu Met Gly Met Leu Ser Thr Ser Leu Ala Asp Gln Asp 
                325                 330                 335     


Ile Phe Asn Ala Val Ile Lys Gln Asn Pro Phe Leu Val Tyr Gln Leu 
            340                 345                 350         


Pro Cys Phe Trp Asn Val Gln Leu Ser Asp His Thr Arg Ser Glu Gln 
        355                 360                 365             


Cys Tyr Arg Asp Val Ser Asp Leu Lys Val Ile His Trp Asn Ser Pro 
    370                 375                 380                 


Lys Lys Leu Arg Val Lys Asn Lys His Val Glu Phe Phe Arg Asn Leu 
385                 390                 395                 400 


Tyr Leu Thr Phe Leu Glu Tyr Asp Gly Asn Leu Leu Arg Arg Glu Leu 
                405                 410                 415     


Phe Gly Cys Pro Ser Glu Ala Asp Val Asn Ser Glu Asn Leu Gln Lys 
            420                 425                 430         


Gln Leu Ser Glu Leu Asp Glu Asp Asp Leu Cys Tyr Glu Phe Arg Arg 
        435                 440                 445             


Glu Arg Phe Thr Val His Arg Thr His Leu Tyr Phe Leu His Tyr Glu 
    450                 455                 460                 


Tyr Glu Pro Ala Ala Asp Ser Thr Asp Val Thr Leu Val Ala Gln Leu 
465                 470                 475                 480 


Ser Met Asp Arg Leu Gln Met Leu Glu Ala Ile Cys Lys His Trp Glu 
                485                 490                 495     


Gly Pro Ile Ser Leu Ala Leu Tyr Leu Ser Asp Ala Glu Ala Gln Gln 
            500                 505                 510         


Phe Leu Arg Tyr Ala Gln Gly Ser Glu Val Leu Met Ser Arg His Asn 
        515                 520                 525             


Val Gly Tyr His Ile Val Tyr Lys Glu Gly Gln Phe Tyr Pro Val Asn 
    530                 535                 540                 


Leu Leu Arg Asn Val Ala Met Lys His Ile Ser Thr Pro Tyr Met Phe 
545                 550                 555                 560 


Leu Ser Asp Ile Asp Phe Leu Pro Met Tyr Gly Leu Tyr Glu Tyr Leu 
                565                 570                 575     


Arg Lys Ser Val Ile Gln Leu Asp Leu Ala Asn Thr Lys Lys Ala Met 
            580                 585                 590         


Ile Val Pro Ala Phe Glu Thr Leu Arg Tyr Arg Leu Ser Phe Pro Lys 
        595                 600                 605             


Ser Lys Ala Glu Leu Leu Ser Met Leu Asp Met Gly Thr Leu Phe Thr 
    610                 615                 620                 


Phe Arg Tyr His Val Trp Thr Lys Gly His Ala Pro Thr Asn Phe Ala 
625                 630                 635                 640 


Lys Trp Arg Thr Ala Thr Thr Pro Tyr Arg Val Glu Trp Glu Ala Asp 
                645                 650                 655     


Phe Glu Pro Tyr Val Val Val Arg Arg Asp Cys Pro Glu Tyr Asp Arg 
            660                 665                 670         


Arg Phe Val Gly Phe Gly Trp Asn Lys Val Ala His Ile Met Glu Leu 
        675                 680                 685             


Asp Val Gln Glu Tyr Glu Phe Ile Val Leu Pro Asn Ala Tyr Met Ile 
    690                 695                 700                 


His Met Pro His Ala Pro Ser Phe Asp Ile Thr Lys Phe Arg Ser Asn 
705                 710                 715                 720 


Lys Gln Tyr Arg Ile Cys Leu Lys Thr Leu Lys Glu Glu Phe Gln Gln 
                725                 730                 735     


Asp Met Ser Arg Arg Tyr Gly Phe Ala Ala Leu Lys Tyr Leu Thr Ala 
            740                 745                 750         


Glu Asn Asn Ser 
        755     


<210>  3501
<211>  264
<212>  PRT
<213>  homo sapiens

<400>  3501

Met Asp Thr Pro Ser Pro Asp Pro Leu Pro Ser Pro Leu Pro Gly Glu 
1               5                   10                  15      


Glu Glu Lys Pro Leu Ala Leu Ser Pro Pro Val Pro Arg Gly Arg Arg 
            20                  25                  30          


Gly Arg Arg Pro Gly Gly Ala Thr Ser Ser Asn Arg Thr Leu Lys Ala 
        35                  40                  45              


Ser Leu Pro Arg Lys Arg Gly Arg Pro Pro Lys Ser Gly Gln Glu Pro 
    50                  55                  60                  


Pro Leu Val Gln Val Gln Gly Val Thr Ala Pro Val Gly Ser Ser Gly 
65                  70                  75                  80  


Gly Ser Asp Leu Leu Leu Ile Asp Asp Gln Gly Val Pro Tyr Thr Val 
                85                  90                  95      


Ser Glu Gly Ser Ala Ala Gly Pro Glu Gly Ser Gly Pro Arg Lys Ala 
            100                 105                 110         


Pro His Phe Cys Pro Val Cys Leu Arg Ala Phe Pro Tyr Leu Ser Asp 
        115                 120                 125             


Leu Glu Arg His Ser Ile Ser His Ser Glu Leu Lys Pro His Gln Cys 
    130                 135                 140                 


Lys Val Cys Gly Lys Thr Phe Lys Arg Ser Ser His Leu Arg Arg His 
145                 150                 155                 160 


Cys Asn Ile His Ala Gly Leu Arg Pro Phe Arg Cys Pro Leu Cys Pro 
                165                 170                 175     


Arg Arg Phe Arg Glu Ala Gly Glu Leu Ala His His His Arg Val His 
            180                 185                 190         


Ser Gly Glu Arg Pro Tyr Gln Cys Pro Ile Cys Arg Leu Arg Phe Thr 
        195                 200                 205             


Glu Ala Asn Thr Leu Arg Arg His Ala Lys Arg Lys His Pro Glu Ala 
    210                 215                 220                 


Met Gly Val Pro Leu Cys Ala Pro Asp Pro Gly Ser Glu Pro Pro Trp 
225                 230                 235                 240 


Asp Glu Glu Gly Ile Pro Ala Thr Ala Gly Ala Glu Glu Glu Glu Glu 
                245                 250                 255     


Thr Glu Gly Lys Gly Glu Pro Ala 
            260                 


<210>  3502
<211>  890
<212>  PRT
<213>  homo sapiens

<400>  3502

Met Asp Ser Glu Arg Gln Val Lys Asp Thr Asp Asp Ile Glu Ser Pro 
1               5                   10                  15      


Lys Arg Ser Ile Arg Asp Ser Gly Tyr Ile Asp Cys Trp Asp Ser Glu 
            20                  25                  30          


Arg Ser Asp Ser Leu Ser Pro Pro Arg His Gly Arg Asp Asp Ser Phe 
        35                  40                  45              


Asp Ser Leu Asp Ser Phe Gly Ser Arg Ser Arg Gln Thr Pro Ser Pro 
    50                  55                  60                  


Asp Val Val Leu Arg Gly Ser Ser Asp Gly Arg Gly Ser Asp Ser Glu 
65                  70                  75                  80  


Ser Asp Leu Pro His Arg Lys Leu Pro Asp Val Lys Lys Asp Asp Met 
                85                  90                  95      


Ser Ala Arg Arg Thr Ser His Gly Glu Pro Lys Ser Ala Val Pro Phe 
            100                 105                 110         


Asn Gln Tyr Leu Pro Asn Lys Ser Asn Gln Thr Ala Tyr Val Pro Ala 
        115                 120                 125             


Pro Leu Arg Lys Lys Lys Ala Glu Arg Glu Glu Tyr Arg Lys Ser Trp 
    130                 135                 140                 


Ser Thr Ala Thr Ser Pro Leu Gly Gly Glu Arg Pro Phe Arg Ser Thr 
145                 150                 155                 160 


Ser Met Phe Asp Met Arg Cys Glu Glu Glu Ala Ala Val Gln Pro His 
                165                 170                 175     


Ser Arg Ala Arg Gln Glu Gln Leu Gln Leu Ile Asn Asn Gln Leu Arg 
            180                 185                 190         


Glu Glu Asp Asp Lys Trp Gln Asp Asp Leu Ala Arg Trp Lys Ser Arg 
        195                 200                 205             


Arg Arg Ser Val Ser Gln Asp Leu Ile Lys Lys Glu Glu Glu Arg Lys 
    210                 215                 220                 


Lys Met Glu Lys Leu Leu Ala Gly Glu Asp Gly Thr Ser Glu Arg Arg 
225                 230                 235                 240 


Lys Ser Ile Lys Thr Tyr Arg Glu Ile Val Gln Glu Lys Glu Arg Arg 
                245                 250                 255     


Glu Arg Glu Leu His Glu Ala Tyr Lys Asn Ala Arg Ser Gln Glu Glu 
            260                 265                 270         


Ala Glu Gly Ile Leu Gln Gln Tyr Ile Glu Arg Phe Thr Ile Ser Glu 
        275                 280                 285             


Ala Val Leu Glu Arg Leu Glu Met Pro Lys Ile Leu Glu Arg Ser His 
    290                 295                 300                 


Ser Thr Glu Pro Asn Leu Ser Ser Phe Leu Asn Asp Pro Asn Pro Met 
305                 310                 315                 320 


Lys Tyr Leu Arg Gln Gln Ser Leu Pro Pro Pro Lys Phe Thr Ala Thr 
                325                 330                 335     


Val Glu Thr Thr Ile Ala Arg Ala Ser Val Leu Asp Thr Ser Met Ser 
            340                 345                 350         


Ala Gly Ser Gly Ser Pro Ser Lys Thr Val Thr Pro Lys Ala Val Pro 
        355                 360                 365             


Met Leu Thr Pro Lys Pro Tyr Ser Gln Pro Lys Asn Ser Gln Asp Val 
    370                 375                 380                 


Leu Lys Thr Phe Lys Val Asp Gly Lys Val Ser Val Asn Gly Glu Thr 
385                 390                 395                 400 


Val His Arg Glu Glu Glu Lys Glu Arg Glu Cys Pro Thr Val Ala Pro 
                405                 410                 415     


Ala His Ser Leu Thr Lys Ser Gln Met Phe Glu Gly Val Ala Arg Val 
            420                 425                 430         


His Gly Ser Pro Leu Glu Leu Lys Gln Asp Asn Gly Ser Ile Glu Ile 
        435                 440                 445             


Asn Ile Lys Lys Pro Asn Ser Val Pro Gln Glu Leu Ala Ala Thr Thr 
    450                 455                 460                 


Glu Lys Thr Glu Pro Asn Ser Gln Glu Asp Lys Asn Asp Gly Gly Lys 
465                 470                 475                 480 


Ser Arg Lys Gly Asn Ile Glu Leu Ala Ser Ser Glu Pro Gln His Phe 
                485                 490                 495     


Thr Thr Thr Val Thr Arg Cys Ser Pro Thr Val Ala Phe Val Glu Phe 
            500                 505                 510         


Pro Ser Ser Pro Gln Leu Lys Asn Asp Val Ser Glu Glu Lys Asp Gln 
        515                 520                 525             


Lys Lys Pro Glu Asn Glu Met Ser Gly Lys Val Glu Leu Val Leu Ser 
    530                 535                 540                 


Gln Lys Val Val Lys Pro Lys Ser Pro Glu Pro Glu Ala Thr Leu Thr 
545                 550                 555                 560 


Phe Pro Phe Leu Asp Lys Met Pro Glu Ala Asn Gln Leu His Leu Pro 
                565                 570                 575     


Asn Leu Asn Ser Gln Val Asp Ser Pro Ser Ser Glu Lys Ser Pro Val 
            580                 585                 590         


Met Thr Pro Phe Lys Phe Trp Ala Trp Asp Pro Glu Glu Glu Arg Arg 
        595                 600                 605             


Arg Gln Glu Lys Trp Gln Gln Glu Gln Glu Arg Leu Leu Gln Glu Arg 
    610                 615                 620                 


Tyr Gln Lys Glu Gln Asp Lys Leu Lys Glu Glu Trp Glu Lys Ala Gln 
625                 630                 635                 640 


Lys Glu Val Glu Glu Glu Glu Arg Arg Tyr Tyr Glu Glu Glu Arg Lys 
                645                 650                 655     


Ile Ile Glu Asp Thr Val Val Pro Phe Thr Val Ser Ser Ser Ser Ala 
            660                 665                 670         


Asp Gln Leu Ser Thr Ser Ser Ser Met Thr Glu Gly Ser Gly Thr Met 
        675                 680                 685             


Asn Lys Ile Asp Leu Gly Asn Cys Gln Asp Glu Lys Gln Asp Arg Arg 
    690                 695                 700                 


Trp Lys Lys Ser Phe Gln Gly Asp Asp Ser Asp Leu Leu Leu Lys Thr 
705                 710                 715                 720 


Arg Glu Ser Asp Arg Leu Glu Glu Lys Gly Ser Leu Thr Glu Gly Ala 
                725                 730                 735     


Leu Ala His Ser Gly Asn Pro Val Ser Lys Gly Val His Glu Asp His 
            740                 745                 750         


Gln Leu Asp Thr Glu Ala Gly Ala Pro His Cys Gly Thr Asn Pro Gln 
        755                 760                 765             


Leu Ala Gln Asp Pro Ser Gln Asn Gln Gln Thr Ser Asn Pro Thr His 
    770                 775                 780                 


Ser Ser Glu Asp Val Lys Pro Lys Thr Leu Pro Leu Asp Lys Ser Ile 
785                 790                 795                 800 


Asn His Gln Ile Glu Ser Pro Ser Glu Arg Arg Lys Ser Ile Ser Gly 
                805                 810                 815     


Lys Lys Leu Cys Ser Ser Cys Gly Leu Pro Leu Gly Lys Gly Ala Ala 
            820                 825                 830         


Met Ile Ile Glu Thr Leu Asn Leu Tyr Phe His Ile Gln Cys Phe Arg 
        835                 840                 845             


Cys Gly Ile Cys Lys Gly Gln Leu Gly Asp Ala Val Ser Gly Thr Asp 
    850                 855                 860                 


Val Arg Ile Arg Asn Gly Leu Leu Asn Cys Asn Asp Cys Tyr Met Arg 
865                 870                 875                 880 


Ser Arg Ser Ala Gly Gln Pro Thr Thr Leu 
                885                 890 


<210>  3503
<211>  1742
<212>  PRT
<213>  homo sapiens

<400>  3503

Met Thr Ser Ser Ser Pro Ala Gly Leu Glu Gly Ser Asp Leu Ser Ser 
1               5                   10                  15      


Ile Asn Thr Met Met Ser Ala Val Met Ser Val Gly Lys Val Thr Glu 
            20                  25                  30          


Asn Gly Gly Ser Pro Gln Gly Ile Lys Ser Pro Ser Lys Pro Pro Gly 
        35                  40                  45              


Pro Asn Arg Ile Gly Arg Arg Asn Gln Glu Thr Lys Glu Glu Lys Ser 
    50                  55                  60                  


Ser Tyr Asn Cys Pro Leu Cys Glu Lys Ile Cys Thr Thr Gln His Gln 
65                  70                  75                  80  


Leu Thr Met His Ile Arg Gln His Asn Thr Asp Thr Gly Gly Ala Asp 
                85                  90                  95      


His Ser Cys Ser Ile Cys Gly Lys Ser Leu Ser Ser Ala Ser Ser Leu 
            100                 105                 110         


Asp Arg His Met Leu Val His Ser Gly Glu Arg Pro Tyr Lys Cys Thr 
        115                 120                 125             


Val Cys Gly Gln Ser Phe Thr Thr Asn Gly Asn Met His Arg His Met 
    130                 135                 140                 


Lys Ile His Glu Lys Asp Pro Asn Ser Ala Thr Ala Thr Ala Pro Pro 
145                 150                 155                 160 


Ser Pro Leu Lys Arg Arg Arg Leu Ser Ser Lys Arg Lys Leu Ser His 
                165                 170                 175     


Asp Ala Glu Ser Glu Arg Glu Asp Pro Ala Pro Ala Lys Lys Met Val 
            180                 185                 190         


Glu Asp Gly Gln Ser Gly Asp Leu Glu Lys Lys Ala Asp Glu Val Phe 
        195                 200                 205             


His Cys Pro Val Cys Phe Lys Glu Phe Val Cys Lys Tyr Gly Leu Glu 
    210                 215                 220                 


Thr His Met Glu Thr His Ser Asp Asn Pro Leu Arg Cys Asp Ile Cys 
225                 230                 235                 240 


Cys Val Thr Phe Arg Thr His Arg Gly Leu Leu Arg His Asn Ala Leu 
                245                 250                 255     


Val His Lys Gln Leu Pro Arg Asp Ala Met Gly Arg Pro Phe Ile Gln 
            260                 265                 270         


Asn Asn Pro Ser Ile Pro Ala Gly Phe His Asp Leu Gly Phe Thr Asp 
        275                 280                 285             


Phe Ser Cys Arg Lys Phe Pro Arg Ile Ser Gln Ala Trp Cys Glu Thr 
    290                 295                 300                 


Asn Leu Arg Arg Cys Ile Ser Glu Gln His Arg Phe Val Cys Asp Thr 
305                 310                 315                 320 


Cys Asp Lys Ala Phe Pro Met Leu Cys Ser Leu Ala Leu His Lys Gln 
                325                 330                 335     


Thr His Val Ala Ala Asp Gln Gly Gln Glu Lys Pro Gln Ala Thr Pro 
            340                 345                 350         


Leu Pro Gly Asp Ala Leu Asp Gln Lys Gly Phe Leu Ala Leu Leu Gly 
        355                 360                 365             


Leu Gln His Thr Lys Asp Val Arg Pro Ala Pro Ala Glu Glu Pro Leu 
    370                 375                 380                 


Pro Asp Asp Asn Gln Ala Ile Gln Leu Gln Thr Leu Lys Cys Gln Leu 
385                 390                 395                 400 


Pro Gln Asp Pro Gly Cys Thr Asn Leu Leu Ser Leu Ser Pro Phe Glu 
                405                 410                 415     


Ala Ala Ser Leu Gly Gly Ser Leu Thr Val Leu Pro Ala Thr Lys Asp 
            420                 425                 430         


Ser Ile Lys His Leu Ser Leu Gln Pro Phe Gln Lys Gly Phe Ile Ile 
        435                 440                 445             


Gln Pro Asp Ser Ser Ile Val Val Lys Pro Ile Ser Gly Glu Ser Ala 
    450                 455                 460                 


Ile Glu Leu Ala Asp Ile Gln Gln Ile Leu Lys Met Ala Ala Ser Ala 
465                 470                 475                 480 


Pro Pro Gln Ile Ser Leu Pro Pro Phe Ser Lys Ala Pro Ala Ala Pro 
                485                 490                 495     


Leu Gln Ala Ile Phe Lys His Met Pro Pro Leu Lys Pro Lys Pro Leu 
            500                 505                 510         


Val Thr Pro Arg Thr Val Val Ala Thr Ser Thr Pro Pro Pro Leu Ile 
        515                 520                 525             


Asn Ala Gln Gln Ala Ser Pro Gly Cys Ile Ser Pro Ser Leu Pro Pro 
    530                 535                 540                 


Pro Pro Leu Lys Leu Leu Lys Gly Ser Val Glu Ala Ala Ser Asn Ala 
545                 550                 555                 560 


His Leu Leu Gln Ser Lys Ser Gly Thr Gln Pro His Ala Ala Thr Arg 
                565                 570                 575     


Leu Ser Leu Gln Gln Pro Arg Ala Glu Leu Pro Gly Gln Pro Glu Met 
            580                 585                 590         


Lys Thr Gln Leu Glu Gln Asp Ser Ile Ile Glu Ala Leu Leu Pro Leu 
        595                 600                 605             


Ser Met Glu Ala Lys Ile Lys Gln Glu Ile Thr Glu Gly Glu Leu Lys 
    610                 615                 620                 


Ala Phe Met Thr Ala Pro Gly Gly Lys Lys Thr Pro Ala Met Arg Lys 
625                 630                 635                 640 


Val Leu Tyr Pro Cys Arg Phe Cys Asn Gln Val Phe Ala Phe Ser Gly 
                645                 650                 655     


Val Leu Arg Ala His Val Arg Ser His Leu Gly Ile Ser Pro Tyr Gln 
            660                 665                 670         


Cys Asn Ile Cys Asp Tyr Ile Ala Ala Asp Lys Ala Ala Leu Ile Arg 
        675                 680                 685             


His Leu Arg Thr His Ser Gly Glu Arg Pro Tyr Ile Cys Lys Ile Cys 
    690                 695                 700                 


His Tyr Pro Phe Thr Val Lys Ala Asn Cys Glu Arg His Leu Arg Lys 
705                 710                 715                 720 


Lys His Leu Lys Ala Thr Arg Lys Asp Ile Glu Lys Asn Ile Glu Tyr 
                725                 730                 735     


Val Ser Ser Ser Ala Ala Glu Leu Val Asp Ala Phe Cys Ala Pro Asp 
            740                 745                 750         


Thr Val Cys Arg Leu Cys Gly Glu Asp Leu Lys His Tyr Arg Ala Leu 
        755                 760                 765             


Arg Ile His Met Arg Thr His Cys Gly Arg Gly Leu Gly Gly Gly His 
    770                 775                 780                 


Lys Gly Arg Lys Pro Phe Glu Cys Lys Glu Cys Ser Ala Ala Phe Ala 
785                 790                 795                 800 


Ala Lys Arg Asn Cys Ile His His Ile Leu Lys Gln His Leu His Val 
                805                 810                 815     


Pro Glu Gln Asp Ile Glu Ser Tyr Val Leu Ala Ala Asp Gly Leu Gly 
            820                 825                 830         


Pro Ala Glu Ala Pro Ala Ala Glu Ala Ser Gly Arg Gly Glu Asp Ser 
        835                 840                 845             


Gly Cys Ala Ala Leu Gly Asp Cys Lys Pro Leu Thr Ala Phe Leu Glu 
    850                 855                 860                 


Pro Gln Asn Gly Phe Leu His Arg Gly Pro Thr Gln Pro Pro Pro Pro 
865                 870                 875                 880 


His Val Ser Ile Lys Leu Glu Pro Ala Ser Ser Phe Ala Val Asp Phe 
                885                 890                 895     


Asn Glu Pro Leu Asp Phe Ser Gln Lys Gly Leu Ala Leu Val Gln Val 
            900                 905                 910         


Lys Gln Glu Asn Ile Ser Phe Leu Ser Pro Ser Ser Leu Val Pro Tyr 
        915                 920                 925             


Asp Cys Ser Met Glu Pro Ile Asp Leu Ser Ile Pro Lys Asn Phe Arg 
    930                 935                 940                 


Lys Gly Asp Lys Asp Leu Ala Thr Pro Ser Glu Ala Lys Lys Pro Glu 
945                 950                 955                 960 


Glu Glu Ala Gly Ser Ser Glu Gln Pro Ser Pro Cys Pro Ala Pro Gly 
                965                 970                 975     


Pro Ser Leu Pro Val Thr Leu Gly Pro Ser Gly Ile Leu Glu Ser Pro 
            980                 985                 990         


Met Ala Pro Ala Pro Ala Ala Thr  Pro Glu Pro Pro Ala  Gln Pro Leu 
        995                 1000                 1005             


Gln Gly  Pro Val Gln Leu Ala  Val Pro Ile Tyr Ser  Ser Ala Leu 
    1010                 1015                 1020             


Val Ser  Ser Pro Pro Leu Val  Gly Ser Ser Ala Leu  Leu Ser Gly 
    1025                 1030                 1035             


Thr Ala  Leu Leu Arg Pro Leu  Arg Pro Lys Pro Pro  Leu Leu Leu 
    1040                 1045                 1050             


Pro Lys  Pro Pro Val Thr Glu  Glu Leu Pro Pro Leu  Ala Ser Ile 
    1055                 1060                 1065             


Ala Gln  Ile Ile Ser Ser Val  Ser Ser Ala Pro Thr  Leu Leu Lys 
    1070                 1075                 1080             


Thr Lys  Val Ala Asp Pro Gly  Pro Ala Ser Thr Gly  Ser Asn Thr 
    1085                 1090                 1095             


Thr Ala  Ser Asp Ser Leu Gly  Gly Ser Val Pro Lys  Ala Ala Thr 
    1100                 1105                 1110             


Thr Ala  Thr Pro Ala Ala Thr  Thr Ser Pro Lys Glu  Ser Ser Glu 
    1115                 1120                 1125             


Pro Pro  Ala Pro Ala Ser Ser  Pro Glu Ala Ala Ser  Pro Thr Glu 
    1130                 1135                 1140             


Gln Gly  Pro Ala Gly Thr Ser  Lys Lys Arg Gly Arg  Lys Arg Gly 
    1145                 1150                 1155             


Met Arg  Ser Arg Pro Arg Ala  Asn Ser Gly Gly Val  Asp Leu Asp 
    1160                 1165                 1170             


Ser Ser  Gly Glu Phe Ala Ser  Ile Glu Lys Met Leu  Ala Thr Thr 
    1175                 1180                 1185             


Asp Thr  Asn Lys Phe Ser Pro  Phe Leu Gln Thr Ala  Glu Asp Asn 
    1190                 1195                 1200             


Thr Gln  Asp Glu Val Ala Gly  Ala Pro Ala Asp His  His Gly Pro 
    1205                 1210                 1215             


Ser Asp  Glu Glu Gln Gly Ser  Pro Pro Glu Asp Lys  Leu Leu Arg 
    1220                 1225                 1230             


Ala Lys  Arg Asn Ser Tyr Thr  Asn Cys Leu Gln Lys  Ile Thr Cys 
    1235                 1240                 1245             


Pro His  Cys Pro Arg Val Phe  Pro Trp Ala Ser Ser  Leu Gln Arg 
    1250                 1255                 1260             


His Met  Leu Thr His Thr Gly  Gln Lys Pro Phe Pro  Cys Gln Lys 
    1265                 1270                 1275             


Cys Asp  Ala Phe Phe Ser Thr  Lys Ser Asn Cys Glu  Arg His Gln 
    1280                 1285                 1290             


Leu Arg  Lys His Gly Val Thr  Thr Cys Ser Leu Arg  Arg Asn Gly 
    1295                 1300                 1305             


Leu Ile  Pro Gln Ser Lys Glu  Ser Asp Val Gly Ser  His Asp Ser 
    1310                 1315                 1320             


Thr Asp  Ser Gln Ser Asp Ala  Glu Thr Ala Ala Ala  Ala Gly Glu 
    1325                 1330                 1335             


Val Leu  Asp Leu Thr Ser Arg  Asp Arg Glu Gln Pro  Ser Glu Gly 
    1340                 1345                 1350             


Ala Thr  Glu Leu Arg Gln Val  Ala Gly Asp Ala Pro  Val Glu Gln 
    1355                 1360                 1365             


Ala Thr  Ala Glu Thr Ala Ser  Pro Val His Arg Glu  Glu His Gly 
    1370                 1375                 1380             


Arg Gly  Glu Ser His Glu Pro  Glu Glu Glu His Gly  Thr Glu Glu 
    1385                 1390                 1395             


Ser Thr  Gly Asp Ala Asp Gly  Ala Glu Glu Asp Ala  Ser Ser Asn 
    1400                 1405                 1410             


Gln Ser  Leu Asp Leu Asp Phe  Ala Thr Lys Leu Met  Asp Phe Lys 
    1415                 1420                 1425             


Leu Ala  Glu Gly Asp Gly Glu  Ala Gly Ala Gly Gly  Ala Ala Ser 
    1430                 1435                 1440             


Gln Glu  Gln Lys Leu Ala Cys  Asp Thr Cys Gly Lys  Ser Phe Lys 
    1445                 1450                 1455             


Phe Leu  Gly Thr Leu Ser Arg  His Arg Lys Ala His  Gly Arg Gln 
    1460                 1465                 1470             


Glu Pro  Lys Asp Glu Lys Gly  Asp Gly Ala Ser Thr  Ala Glu Glu 
    1475                 1480                 1485             


Gly Pro  Gln Pro Ala Pro Glu  Gln Glu Glu Lys Pro  Pro Glu Thr 
    1490                 1495                 1500             


Pro Ala  Glu Val Val Glu Ser  Ala Pro Gly Ala Gly  Glu Ala Pro 
    1505                 1510                 1515             


Ala Glu  Lys Leu Ala Glu Glu  Thr Glu Gly Pro Ser  Asp Gly Glu 
    1520                 1525                 1530             


Ser Ala  Ala Glu Lys Arg Ser  Ser Glu Lys Ser Asp  Asp Asp Lys 
    1535                 1540                 1545             


Lys Pro  Lys Thr Asp Ser Pro  Lys Ser Val Ala Ser  Lys Ala Asp 
    1550                 1555                 1560             


Lys Arg  Lys Lys Val Cys Ser  Val Cys Asn Lys Arg  Phe Trp Ser 
    1565                 1570                 1575             


Leu Gln  Asp Leu Thr Arg His  Met Arg Ser His Thr  Gly Glu Arg 
    1580                 1585                 1590             


Pro Tyr  Lys Cys Gln Thr Cys  Glu Arg Thr Phe Thr  Leu Lys His 
    1595                 1600                 1605             


Ser Leu  Val Arg His Gln Arg  Ile His Gln Lys Ala  Arg His Ala 
    1610                 1615                 1620             


Lys His  His Gly Lys Asp Ser  Asp Lys Glu Glu Arg  Gly Glu Glu 
    1625                 1630                 1635             


Asp Ser  Glu Asn Glu Ser Thr  His Ser Gly Asn Asn  Ala Val Ser 
    1640                 1645                 1650             


Glu Asn  Glu Ala Glu Leu Ala  Pro Asn Ala Ser Asn  His Met Ala 
    1655                 1660                 1665             


Val Thr  Arg Ser Arg Lys Glu  Gly Leu Ala Ser Ala  Thr Lys Asp 
    1670                 1675                 1680             


Cys Ser  His Arg Glu Glu Lys  Val Thr Ala Gly Trp  Pro Ser Glu 
    1685                 1690                 1695             


Pro Gly  Gln Gly Asp Leu Asn  Pro Glu Ser Pro Ala  Ala Leu Gly 
    1700                 1705                 1710             


Gln Asp  Leu Leu Glu Pro Arg  Ser Lys Arg Pro Ala  His Pro Ile 
    1715                 1720                 1725             


Leu Ala  Thr Ala Asp Gly Ala  Ser Gln Leu Val Gly  Met Glu 
    1730                 1735                 1740         


<210>  3504
<211>  1687
<212>  PRT
<213>  homo sapiens

<400>  3504

Met Thr Ser Ser Ser Pro Ala Gly Leu Glu Gly Ser Asp Leu Ser Ser 
1               5                   10                  15      


Ile Asn Thr Met Met Ser Ala Val Met Ser Val Gly Lys Val Thr Glu 
            20                  25                  30          


Asn Gly Gly Ser Pro Gln Gly Ile Lys Ser Pro Ser Lys Pro Pro Gly 
        35                  40                  45              


Pro Asn Arg Ile Gly Arg Arg Asn Gln Glu Thr Lys Glu Glu Lys Ser 
    50                  55                  60                  


Ser Tyr Asn Cys Pro Leu Cys Glu Lys Ile Cys Thr Thr Gln His Gln 
65                  70                  75                  80  


Leu Thr Met His Ile Arg Gln His Asn Thr Asp Thr Gly Gly Ala Asp 
                85                  90                  95      


His Ser Cys Ser Ile Cys Gly Lys Ser Leu Ser Ser Ala Ser Ser Leu 
            100                 105                 110         


Asp Arg His Met Leu Val His Ser Gly Glu Arg Pro Tyr Lys Cys Thr 
        115                 120                 125             


Val Cys Gly Gln Ser Phe Thr Thr Asn Gly Asn Met His Arg His Met 
    130                 135                 140                 


Lys Ile His Glu Lys Asp Pro Asn Ser Ala Thr Ala Thr Ala Pro Pro 
145                 150                 155                 160 


Ser Pro Leu Lys Arg Arg Arg Leu Ser Ser Lys Arg Lys Leu Ser His 
                165                 170                 175     


Asp Ala Glu Ser Glu Arg Glu Asp Pro Ala Pro Ala Lys Lys Met Val 
            180                 185                 190         


Glu Asp Gly Gln Ser Gly Asp Leu Glu Lys Lys Ala Asp Glu Val Phe 
        195                 200                 205             


His Cys Pro Val Cys Phe Lys Glu Phe Val Cys Lys Tyr Gly Leu Glu 
    210                 215                 220                 


Thr His Met Glu Thr His Ser Asp Asn Pro Leu Arg Cys Asp Ile Cys 
225                 230                 235                 240 


Cys Val Thr Phe Arg Thr His Arg Gly Leu Leu Arg His Asn Ala Leu 
                245                 250                 255     


Val His Lys Gln Leu Pro Arg Asp Ala Met Gly Arg Pro Phe Ile Gln 
            260                 265                 270         


Asn Asn Pro Ser Ile Pro Ala Gly Phe His Asp Leu Gly Phe Thr Asp 
        275                 280                 285             


Phe Ser Cys Arg Lys Phe Pro Arg Ile Ser Gln Ala Trp Cys Glu Thr 
    290                 295                 300                 


Asn Leu Arg Arg Cys Ile Ser Glu Gln His Arg Phe Val Cys Asp Thr 
305                 310                 315                 320 


Cys Asp Lys Ala Phe Pro Met Leu Cys Ser Leu Ala Leu His Lys Gln 
                325                 330                 335     


Thr His Val Ala Ala Asp Gln Gly Gln Glu Lys Pro Gln Ala Thr Pro 
            340                 345                 350         


Leu Pro Gly Asp Ala Leu Asp Gln Lys Gly Phe Leu Ala Leu Leu Gly 
        355                 360                 365             


Leu Gln His Thr Lys Asp Val Arg Pro Ala Pro Ala Glu Glu Pro Leu 
    370                 375                 380                 


Pro Asp Asp Asn Gln Ala Ile Gln Leu Gln Thr Leu Lys Cys Gln Leu 
385                 390                 395                 400 


Pro Gln Asp Pro Gly Cys Thr Asn Leu Leu Ser Leu Ser Pro Phe Glu 
                405                 410                 415     


Ala Ala Ser Leu Gly Gly Ser Leu Thr Val Leu Pro Ala Thr Lys Asp 
            420                 425                 430         


Ser Ile Lys His Leu Ser Leu Gln Pro Phe Gln Lys Gly Phe Ile Ile 
        435                 440                 445             


Gln Pro Asp Ser Ser Ile Val Val Lys Pro Ile Ser Gly Glu Ser Ala 
    450                 455                 460                 


Ile Glu Leu Ala Asp Ile Gln Gln Ile Leu Lys Met Ala Ala Ser Ala 
465                 470                 475                 480 


Pro Pro Gln Ile Ser Leu Pro Pro Phe Ser Lys Ala Pro Ala Ala Pro 
                485                 490                 495     


Leu Gln Ala Ile Phe Lys His Met Pro Pro Leu Lys Pro Lys Pro Leu 
            500                 505                 510         


Val Thr Pro Arg Thr Val Val Ala Thr Ser Thr Pro Pro Pro Leu Ile 
        515                 520                 525             


Asn Ala Gln Gln Ala Ser Pro Gly Cys Ile Ser Pro Ser Leu Pro Pro 
    530                 535                 540                 


Pro Pro Leu Lys Leu Leu Lys Gly Ser Val Glu Ala Ala Ser Asn Ala 
545                 550                 555                 560 


His Leu Leu Gln Ser Lys Ser Gly Thr Gln Pro His Ala Ala Thr Arg 
                565                 570                 575     


Leu Ser Leu Gln Gln Pro Arg Ala Glu Leu Pro Gly Gln Pro Glu Met 
            580                 585                 590         


Lys Thr Gln Leu Glu Gln Asp Ser Ile Ile Glu Ala Leu Leu Pro Leu 
        595                 600                 605             


Ser Met Glu Ala Lys Ile Lys Gln Glu Ile Thr Glu Gly Glu Leu Lys 
    610                 615                 620                 


Ala Phe Met Thr Ala Pro Gly Gly Lys Lys Thr Pro Ala Met Arg Lys 
625                 630                 635                 640 


Val Leu Tyr Pro Cys Arg Phe Cys Asn Gln Val Phe Ala Phe Ser Gly 
                645                 650                 655     


Val Leu Arg Ala His Val Arg Ser His Leu Gly Ile Ser Pro Tyr Gln 
            660                 665                 670         


Cys Asn Ile Cys Asp Tyr Ile Ala Ala Asp Lys Ala Ala Leu Ile Arg 
        675                 680                 685             


His Leu Arg Thr His Ser Gly Glu Arg Pro Tyr Ile Cys Lys Ile Cys 
    690                 695                 700                 


His Tyr Pro Phe Thr Val Lys Ala Asn Cys Glu Arg His Leu Arg Lys 
705                 710                 715                 720 


Lys His Leu Lys Ala Thr Arg Lys Asp Ile Glu Lys Asn Ile Glu Tyr 
                725                 730                 735     


Val Ser Ser Ser Ala Ala Glu Leu Val Asp Ala Phe Cys Ala Pro Asp 
            740                 745                 750         


Thr Val Cys Arg Leu Cys Gly Glu Asp Leu Lys His Tyr Arg Ala Leu 
        755                 760                 765             


Arg Ile His Met Arg Thr His Cys Gly Arg Gly Leu Gly Gly Gly His 
    770                 775                 780                 


Lys Gly Arg Lys Pro Phe Glu Cys Lys Glu Cys Ser Ala Ala Phe Ala 
785                 790                 795                 800 


Ala Lys Arg Asn Cys Ile His His Ile Leu Lys Gln His Leu His Val 
                805                 810                 815     


Pro Glu Gln Asp Ile Glu Ser Tyr Val Leu Ala Ala Asp Gly Leu Gly 
            820                 825                 830         


Pro Ala Glu Ala Pro Ala Ala Glu Ala Ser Gly Arg Gly Glu Asp Ser 
        835                 840                 845             


Gly Cys Ala Ala Leu Gly Asp Cys Lys Pro Leu Thr Ala Phe Leu Glu 
    850                 855                 860                 


Pro Gln Asn Gly Phe Leu His Arg Gly Pro Thr Gln Pro Pro Pro Pro 
865                 870                 875                 880 


His Val Ser Ile Lys Leu Glu Pro Ala Ser Ser Phe Ala Val Asp Phe 
                885                 890                 895     


Asn Glu Pro Leu Asp Phe Ser Gln Lys Gly Leu Ala Leu Val Gln Val 
            900                 905                 910         


Lys Gln Glu Asn Ile Ser Phe Leu Ser Pro Ser Ser Leu Val Pro Tyr 
        915                 920                 925             


Asp Cys Ser Met Glu Pro Ile Asp Leu Ser Ile Pro Lys Asn Phe Arg 
    930                 935                 940                 


Lys Gly Asp Lys Asp Leu Ala Thr Pro Ser Glu Ala Lys Lys Pro Glu 
945                 950                 955                 960 


Glu Glu Ala Gly Ser Ser Glu Gln Pro Ser Pro Cys Pro Ala Pro Gly 
                965                 970                 975     


Pro Ser Leu Pro Val Thr Leu Gly Pro Ser Gly Ile Leu Glu Ser Pro 
            980                 985                 990         


Met Ala Pro Ala Pro Ala Ala Thr  Pro Glu Pro Pro Ala  Gln Pro Leu 
        995                 1000                 1005             


Gln Gly  Pro Val Gln Leu Ala  Val Pro Ile Tyr Ser  Ser Ala Leu 
    1010                 1015                 1020             


Val Ser  Ser Pro Pro Leu Val  Gly Ser Ser Ala Leu  Leu Ser Gly 
    1025                 1030                 1035             


Thr Ala  Leu Leu Arg Pro Leu  Arg Pro Lys Pro Pro  Leu Leu Leu 
    1040                 1045                 1050             


Pro Lys  Pro Pro Val Thr Glu  Glu Leu Pro Pro Leu  Ala Ser Ile 
    1055                 1060                 1065             


Ala Gln  Ile Ile Ser Ser Val  Ser Ser Ala Pro Thr  Leu Leu Lys 
    1070                 1075                 1080             


Thr Lys  Val Ala Asp Pro Gly  Pro Ala Ser Thr Gly  Ser Asn Thr 
    1085                 1090                 1095             


Thr Ala  Ser Asp Ser Leu Gly  Gly Ser Val Pro Lys  Ala Ala Thr 
    1100                 1105                 1110             


Thr Ala  Thr Pro Ala Ala Thr  Thr Ser Pro Lys Glu  Ser Ser Glu 
    1115                 1120                 1125             


Pro Pro  Ala Pro Ala Ser Ser  Pro Glu Ala Ala Ser  Pro Thr Glu 
    1130                 1135                 1140             


Gln Gly  Pro Ala Gly Thr Ser  Lys Lys Arg Gly Arg  Lys Arg Gly 
    1145                 1150                 1155             


Met Arg  Ser Arg Pro Arg Ala  Asn Ser Gly Gly Val  Asp Leu Asp 
    1160                 1165                 1170             


Ser Ser  Gly Glu Phe Ala Ser  Ile Glu Lys Met Leu  Ala Thr Thr 
    1175                 1180                 1185             


Asp Thr  Asn Lys Phe Ser Pro  Phe Leu Gln Thr Ala  Glu Asp Asn 
    1190                 1195                 1200             


Thr Gln  Asp Glu Val Ala Gly  Ala Pro Ala Asp His  His Gly Pro 
    1205                 1210                 1215             


Ser Asp  Glu Glu Gln Gly Ser  Pro Pro Glu Asp Lys  Leu Leu Arg 
    1220                 1225                 1230             


Ala Lys  Arg Asn Ser Tyr Thr  Asn Cys Leu Gln Lys  Ile Thr Cys 
    1235                 1240                 1245             


Pro His  Cys Pro Arg Val Phe  Pro Trp Ala Ser Ser  Leu Gln Arg 
    1250                 1255                 1260             


His Met  Leu Thr His Thr Asp  Ser Gln Ser Asp Ala  Glu Thr Ala 
    1265                 1270                 1275             


Ala Ala  Ala Gly Glu Val Leu  Asp Leu Thr Ser Arg  Asp Arg Glu 
    1280                 1285                 1290             


Gln Pro  Ser Glu Gly Ala Thr  Glu Leu Arg Gln Val  Ala Gly Asp 
    1295                 1300                 1305             


Ala Pro  Val Glu Gln Ala Thr  Ala Glu Thr Ala Ser  Pro Val His 
    1310                 1315                 1320             


Arg Glu  Glu His Gly Arg Gly  Glu Ser His Glu Pro  Glu Glu Glu 
    1325                 1330                 1335             


His Gly  Thr Glu Glu Ser Thr  Gly Asp Ala Asp Gly  Ala Glu Glu 
    1340                 1345                 1350             


Asp Ala  Ser Ser Asn Gln Ser  Leu Asp Leu Asp Phe  Ala Thr Lys 
    1355                 1360                 1365             


Leu Met  Asp Phe Lys Leu Ala  Glu Gly Asp Gly Glu  Ala Gly Ala 
    1370                 1375                 1380             


Gly Gly  Ala Ala Ser Gln Glu  Gln Lys Leu Ala Cys  Asp Thr Cys 
    1385                 1390                 1395             


Gly Lys  Ser Phe Lys Phe Leu  Gly Thr Leu Ser Arg  His Arg Lys 
    1400                 1405                 1410             


Ala His  Gly Arg Gln Glu Pro  Lys Asp Glu Lys Gly  Asp Gly Ala 
    1415                 1420                 1425             


Ser Thr  Ala Glu Glu Gly Pro  Gln Pro Ala Pro Glu  Gln Glu Glu 
    1430                 1435                 1440             


Lys Pro  Pro Glu Thr Pro Ala  Glu Val Val Glu Ser  Ala Pro Gly 
    1445                 1450                 1455             


Ala Gly  Glu Ala Pro Ala Glu  Lys Leu Ala Glu Glu  Thr Glu Gly 
    1460                 1465                 1470             


Pro Ser  Asp Gly Glu Ser Ala  Ala Glu Lys Arg Ser  Ser Glu Lys 
    1475                 1480                 1485             


Ser Asp  Asp Asp Lys Lys Pro  Lys Thr Asp Ser Pro  Lys Ser Val 
    1490                 1495                 1500             


Ala Ser  Lys Ala Asp Lys Arg  Lys Lys Val Cys Ser  Val Cys Asn 
    1505                 1510                 1515             


Lys Arg  Phe Trp Ser Leu Gln  Asp Leu Thr Arg His  Met Arg Ser 
    1520                 1525                 1530             


His Thr  Gly Glu Arg Pro Tyr  Lys Cys Gln Thr Cys  Glu Arg Thr 
    1535                 1540                 1545             


Phe Thr  Leu Lys His Ser Leu  Val Arg His Gln Arg  Ile His Gln 
    1550                 1555                 1560             


Lys Ala  Arg His Ala Lys His  His Gly Lys Asp Ser  Asp Lys Glu 
    1565                 1570                 1575             


Glu Arg  Gly Glu Glu Asp Ser  Glu Asn Glu Ser Thr  His Ser Gly 
    1580                 1585                 1590             


Asn Asn  Ala Val Ser Glu Asn  Glu Ala Glu Leu Ala  Pro Asn Ala 
    1595                 1600                 1605             


Ser Asn  His Met Ala Val Thr  Arg Ser Arg Lys Glu  Gly Leu Ala 
    1610                 1615                 1620             


Ser Ala  Thr Lys Asp Cys Ser  His Arg Glu Glu Lys  Val Thr Ala 
    1625                 1630                 1635             


Gly Trp  Pro Ser Glu Pro Gly  Gln Gly Asp Leu Asn  Pro Glu Ser 
    1640                 1645                 1650             


Pro Ala  Ala Leu Gly Gln Asp  Leu Leu Glu Pro Arg  Ser Lys Arg 
    1655                 1660                 1665             


Pro Ala  His Pro Ile Leu Ala  Thr Ala Asp Gly Ala  Ser Gln Leu 
    1670                 1675                 1680             


Val Gly  Met Glu 
    1685         


<210>  3505
<211>  835
<212>  PRT
<213>  homo sapiens

<400>  3505

Met Ala Ala Ser Ala Ala Ala Ala Ser Ala Ala Ala Ala Ser Ala Ala 
1               5                   10                  15      


Ser Gly Ser Pro Gly Pro Gly Glu Gly Ser Ala Gly Gly Glu Lys Arg 
            20                  25                  30          


Ser Thr Ala Pro Ser Ala Ala Ala Ser Ala Ser Ala Ser Ala Ala Ala 
        35                  40                  45              


Ser Ser Pro Ala Gly Gly Gly Ala Glu Ala Leu Glu Leu Leu Glu His 
    50                  55                  60                  


Cys Gly Val Cys Arg Glu Arg Leu Arg Pro Glu Arg Glu Pro Arg Leu 
65                  70                  75                  80  


Leu Pro Cys Leu His Ser Ala Cys Ser Ala Cys Leu Gly Pro Ala Ala 
                85                  90                  95      


Pro Ala Ala Ala Asn Ser Ser Gly Asp Gly Gly Ala Ala Gly Asp Gly 
            100                 105                 110         


Thr Val Val Asp Cys Pro Val Cys Lys Gln Gln Cys Phe Ser Lys Asp 
        115                 120                 125             


Ile Val Glu Asn Tyr Phe Met Arg Asp Ser Gly Ser Lys Ala Ala Thr 
    130                 135                 140                 


Asp Ala Gln Asp Ala Asn Gln Cys Cys Thr Ser Cys Glu Asp Asn Ala 
145                 150                 155                 160 


Pro Ala Thr Ser Tyr Cys Val Glu Cys Ser Glu Pro Leu Cys Glu Thr 
                165                 170                 175     


Cys Val Glu Ala His Gln Arg Val Lys Tyr Thr Lys Asp His Thr Val 
            180                 185                 190         


Arg Ser Thr Gly Pro Ala Lys Ser Arg Asp Gly Glu Arg Thr Val Tyr 
        195                 200                 205             


Cys Asn Val His Lys His Glu Pro Leu Val Leu Phe Cys Glu Ser Cys 
    210                 215                 220                 


Asp Thr Leu Thr Cys Arg Asp Cys Gln Leu Asn Ala His Lys Asp His 
225                 230                 235                 240 


Gln Tyr Gln Phe Leu Glu Asp Ala Val Arg Asn Gln Arg Lys Leu Leu 
                245                 250                 255     


Ala Ser Leu Val Lys Arg Leu Gly Asp Lys His Ala Thr Leu Gln Lys 
            260                 265                 270         


Ser Thr Lys Glu Val Arg Ser Ser Ile Arg Gln Val Ser Asp Val Gln 
        275                 280                 285             


Lys Arg Val Gln Val Asp Val Lys Met Ala Ile Leu Gln Ile Met Lys 
    290                 295                 300                 


Glu Leu Asn Lys Arg Gly Arg Val Leu Val Asn Asp Ala Gln Lys Val 
305                 310                 315                 320 


Thr Glu Gly Gln Gln Glu Arg Leu Glu Arg Gln His Trp Thr Met Thr 
                325                 330                 335     


Lys Ile Gln Lys His Gln Glu His Ile Leu Arg Phe Ala Ser Trp Ala 
            340                 345                 350         


Leu Glu Ser Asp Asn Asn Thr Ala Leu Leu Leu Ser Lys Lys Leu Ile 
        355                 360                 365             


Tyr Phe Gln Leu His Arg Ala Leu Lys Met Ile Val Asp Pro Val Glu 
    370                 375                 380                 


Pro His Gly Glu Met Lys Phe Gln Trp Asp Leu Asn Ala Trp Thr Lys 
385                 390                 395                 400 


Ser Ala Glu Ala Phe Gly Lys Ile Val Ala Glu Arg Pro Gly Thr Asn 
                405                 410                 415     


Ser Thr Gly Pro Ala Pro Met Ala Pro Pro Arg Ala Pro Gly Pro Leu 
            420                 425                 430         


Ser Lys Gln Gly Ser Gly Ser Ser Gln Pro Met Glu Val Gln Glu Gly 
        435                 440                 445             


Tyr Gly Phe Gly Ser Gly Asp Asp Pro Tyr Ser Ser Ala Glu Pro His 
    450                 455                 460                 


Val Ser Gly Val Lys Arg Ser Arg Ser Gly Glu Gly Glu Val Ser Gly 
465                 470                 475                 480 


Leu Met Arg Lys Val Pro Arg Val Ser Leu Glu Arg Leu Asp Leu Asp 
                485                 490                 495     


Leu Thr Ala Asp Ser Gln Pro Pro Val Phe Lys Val Phe Pro Gly Ser 
            500                 505                 510         


Thr Thr Glu Asp Tyr Asn Leu Ile Val Ile Glu Arg Gly Ala Ala Ala 
        515                 520                 525             


Ala Ala Thr Gly Gln Pro Gly Thr Ala Pro Ala Gly Thr Pro Gly Ala 
    530                 535                 540                 


Pro Pro Leu Ala Gly Met Ala Ile Val Lys Glu Glu Glu Thr Glu Ala 
545                 550                 555                 560 


Ala Ile Gly Ala Pro Pro Thr Ala Thr Glu Gly Pro Glu Thr Lys Pro 
                565                 570                 575     


Val Leu Met Ala Leu Ala Glu Gly Pro Gly Ala Glu Gly Pro Arg Leu 
            580                 585                 590         


Ala Ser Pro Ser Gly Ser Thr Ser Ser Gly Leu Glu Val Val Ala Pro 
        595                 600                 605             


Glu Gly Thr Ser Ala Pro Gly Gly Gly Pro Gly Thr Leu Asp Asp Ser 
    610                 615                 620                 


Ala Thr Ile Cys Arg Val Cys Gln Lys Pro Gly Asp Leu Val Met Cys 
625                 630                 635                 640 


Asn Gln Cys Glu Phe Cys Phe His Leu Asp Cys His Leu Pro Ala Leu 
                645                 650                 655     


Gln Asp Val Pro Gly Glu Glu Trp Ser Cys Ser Leu Cys His Val Leu 
            660                 665                 670         


Pro Asp Leu Lys Glu Glu Asp Gly Ser Leu Ser Leu Asp Gly Ala Asp 
        675                 680                 685             


Ser Thr Gly Val Val Ala Lys Leu Ser Pro Ala Asn Gln Arg Lys Cys 
    690                 695                 700                 


Glu Arg Val Leu Leu Ala Leu Phe Cys His Glu Pro Cys Arg Pro Leu 
705                 710                 715                 720 


His Gln Leu Ala Thr Asp Ser Thr Phe Ser Leu Asp Gln Pro Gly Gly 
                725                 730                 735     


Thr Leu Asp Leu Thr Leu Ile Arg Ala Arg Leu Gln Glu Lys Leu Ser 
            740                 745                 750         


Pro Pro Tyr Ser Ser Pro Gln Glu Phe Ala Gln Asp Val Gly Arg Met 
        755                 760                 765             


Phe Lys Gln Phe Asn Lys Leu Thr Glu Asp Lys Ala Asp Val Gln Ser 
    770                 775                 780                 


Ile Ile Gly Leu Gln Arg Phe Phe Glu Thr Arg Met Asn Glu Ala Phe 
785                 790                 795                 800 


Gly Asp Thr Lys Phe Ser Ala Val Leu Val Glu Pro Pro Pro Met Ser 
                805                 810                 815     


Leu Pro Gly Ala Gly Leu Ser Ser Gln Glu Leu Ser Gly Gly Pro Gly 
            820                 825                 830         


Asp Gly Pro 
        835 


<210>  3506
<211>  630
<212>  PRT
<213>  homo sapiens

<400>  3506

Met Ala Ala Val Ala Met Thr Pro Asn Pro Val Gln Thr Leu Gln Glu 
1               5                   10                  15      


Glu Ala Val Cys Ala Ile Cys Leu Asp Tyr Phe Thr Asp Pro Val Ser 
            20                  25                  30          


Ile Gly Cys Gly His Asn Phe Cys Arg Val Cys Val Thr Gln Leu Trp 
        35                  40                  45              


Gly Gly Glu Asp Glu Glu Asp Arg Asp Glu Leu Asp Arg Glu Glu Glu 
    50                  55                  60                  


Glu Glu Asp Gly Glu Glu Glu Glu Val Glu Ala Val Gly Ala Gly Ala 
65                  70                  75                  80  


Gly Trp Asp Thr Pro Met Arg Asp Glu Asp Tyr Glu Gly Asp Met Glu 
                85                  90                  95      


Glu Glu Val Glu Glu Glu Glu Glu Gly Val Phe Trp Thr Ser Gly Met 
            100                 105                 110         


Ser Arg Ser Ser Trp Asp Asn Met Asp Tyr Val Trp Glu Glu Glu Asp 
        115                 120                 125             


Glu Glu Glu Asp Leu Asp Tyr Tyr Leu Gly Asp Met Glu Glu Glu Asp 
    130                 135                 140                 


Leu Arg Gly Glu Asp Glu Glu Asp Glu Glu Glu Val Leu Glu Glu Val 
145                 150                 155                 160 


Glu Glu Glu Asp Leu Asp Pro Val Thr Pro Leu Pro Pro Pro Pro Ala 
                165                 170                 175     


Pro Arg Arg Cys Phe Thr Cys Pro Gln Cys Arg Lys Ser Phe Pro Arg 
            180                 185                 190         


Arg Ser Phe Arg Pro Asn Leu Gln Leu Ala Asn Met Val Gln Val Ile 
        195                 200                 205             


Arg Gln Met His Pro Thr Pro Gly Arg Gly Ser Arg Val Thr Asp Gln 
    210                 215                 220                 


Gly Ile Cys Pro Lys His Gln Glu Ala Leu Lys Leu Phe Cys Glu Val 
225                 230                 235                 240 


Asp Glu Glu Ala Ile Cys Val Val Cys Arg Glu Ser Arg Ser His Lys 
                245                 250                 255     


Gln His Ser Val Val Pro Leu Glu Glu Val Val Gln Glu Tyr Lys Ala 
            260                 265                 270         


Lys Leu Gln Gly His Val Glu Pro Leu Arg Lys His Leu Glu Ala Val 
        275                 280                 285             


Gln Lys Met Lys Ala Lys Glu Glu Arg Arg Val Thr Glu Leu Lys Ser 
    290                 295                 300                 


Gln Met Lys Ser Glu Leu Ala Ala Val Ala Ser Glu Phe Gly Arg Leu 
305                 310                 315                 320 


Thr Arg Phe Leu Ala Glu Glu Gln Ala Gly Leu Glu Arg Arg Leu Arg 
                325                 330                 335     


Glu Met His Glu Ala Gln Leu Gly Arg Ala Gly Ala Ala Ala Ser Arg 
            340                 345                 350         


Leu Ala Glu Gln Ala Ala Gln Leu Ser Arg Leu Leu Ala Glu Ala Gln 
        355                 360                 365             


Glu Arg Ser Gln Gln Gly Gly Leu Arg Leu Leu Gln Asp Ile Lys Glu 
    370                 375                 380                 


Thr Phe Asn Arg Cys Glu Glu Val Gln Leu Gln Pro Pro Glu Val Trp 
385                 390                 395                 400 


Ser Pro Asp Pro Cys Gln Pro His Ser His Asp Phe Leu Thr Asp Ala 
                405                 410                 415     


Ile Val Arg Lys Met Ser Arg Met Phe Cys Gln Ala Ala Arg Val Asp 
            420                 425                 430         


Leu Thr Leu Asp Pro Asp Thr Ala His Pro Ala Leu Met Leu Ser Pro 
        435                 440                 445             


Asp Arg Arg Gly Val Arg Leu Ala Glu Arg Arg Gln Glu Val Ala Asp 
    450                 455                 460                 


His Pro Lys Arg Phe Ser Ala Asp Cys Cys Val Leu Gly Ala Gln Gly 
465                 470                 475                 480 


Phe Arg Ser Gly Arg His Tyr Trp Glu Val Glu Val Gly Gly Arg Arg 
                485                 490                 495     


Gly Trp Ala Val Gly Ala Ala Arg Glu Ser Thr His His Lys Glu Lys 
            500                 505                 510         


Val Gly Pro Gly Gly Ser Ser Val Gly Ser Gly Asp Ala Ser Ser Ser 
        515                 520                 525             


Arg His His His Arg Arg Arg Arg Leu His Leu Pro Gln Gln Pro Leu 
    530                 535                 540                 


Leu Gln Arg Glu Val Trp Cys Val Gly Thr Asn Gly Lys Arg Tyr Gln 
545                 550                 555                 560 


Ala Gln Ser Ser Thr Glu Gln Thr Leu Leu Ser Pro Ser Glu Lys Pro 
                565                 570                 575     


Arg Arg Phe Gly Val Tyr Leu Asp Tyr Glu Ala Gly Arg Leu Gly Phe 
            580                 585                 590         


Tyr Asn Ala Glu Thr Leu Ala His Val His Thr Phe Ser Ala Ala Phe 
        595                 600                 605             


Leu Gly Glu Arg Val Phe Pro Phe Phe Arg Val Leu Ser Lys Gly Thr 
    610                 615                 620                 


Arg Ile Lys Leu Cys Pro 
625                 630 


<210>  3507
<211>  518
<212>  PRT
<213>  homo sapiens

<400>  3507

Met Ala Ala Val Ala Met Thr Pro Asn Pro Val Gln Thr Leu Gln Glu 
1               5                   10                  15      


Glu Ala Val Cys Ala Ile Cys Leu Asp Tyr Phe Thr Asp Pro Val Ser 
            20                  25                  30          


Ile Gly Cys Gly His Asn Phe Cys Arg Val Cys Val Thr Gln Leu Trp 
        35                  40                  45              


Gly Gly Glu Asp Glu Glu Asp Arg Asp Glu Leu Asp Arg Glu Glu Glu 
    50                  55                  60                  


Glu Glu Asp Gly Glu Glu Glu Glu Val Glu Ala Val Gly Ala Gly Ala 
65                  70                  75                  80  


Gly Trp Asp Thr Pro Met Arg Asp Glu Asp Tyr Glu Gly Asp Met Glu 
                85                  90                  95      


Glu Glu Val Glu Glu Glu Glu Glu Gly Val Phe Trp Thr Ser Gly Met 
            100                 105                 110         


Ser Arg Ser Ser Trp Asp Asn Met Asp Tyr Val Trp Glu Glu Glu Asp 
        115                 120                 125             


Glu Glu Glu Asp Leu Asp Tyr Tyr Leu Gly Asp Met Glu Glu Glu Asp 
    130                 135                 140                 


Leu Arg Gly Glu Asp Glu Glu Asp Glu Glu Glu Val Leu Glu Glu Val 
145                 150                 155                 160 


Glu Glu Glu Asp Leu Asp Pro Val Thr Pro Leu Pro Pro Pro Pro Ala 
                165                 170                 175     


Pro Arg Arg Cys Phe Thr Cys Pro Gln Cys Arg Lys Ser Phe Pro Arg 
            180                 185                 190         


Arg Ser Phe Arg Pro Asn Leu Gln Leu Ala Asn Met Val Gln Val Ile 
        195                 200                 205             


Arg Gln Met His Pro Thr Pro Gly Arg Gly Ser Arg Val Thr Asp Gln 
    210                 215                 220                 


Gly Ile Cys Pro Lys His Gln Glu Ala Leu Lys Leu Phe Cys Glu Val 
225                 230                 235                 240 


Asp Glu Glu Ala Ile Cys Val Val Cys Arg Glu Ser Arg Ser His Lys 
                245                 250                 255     


Gln His Ser Val Val Pro Leu Glu Glu Val Val Gln Glu Tyr Lys Ala 
            260                 265                 270         


Lys Leu Gln Gly His Val Glu Pro Leu Arg Lys His Leu Glu Ala Val 
        275                 280                 285             


Gln Lys Met Lys Ala Lys Glu Glu Arg Arg Val Thr Glu Leu Lys Ser 
    290                 295                 300                 


Gln Met Lys Ser Glu Leu Ala Ala Val Ala Ser Glu Phe Gly Arg Leu 
305                 310                 315                 320 


Thr Arg Phe Leu Ala Glu Glu Gln Ala Gly Leu Glu Arg Arg Leu Arg 
                325                 330                 335     


Glu Met His Glu Ala Gln Leu Gly Arg Ala Gly Ala Ala Ala Ser Arg 
            340                 345                 350         


Leu Ala Glu Gln Ala Ala Gln Leu Ser Arg Leu Leu Ala Glu Ala Gln 
        355                 360                 365             


Glu Arg Ser Gln Gln Gly Gly Leu Arg Leu Leu Gln Asp Ile Lys Glu 
    370                 375                 380                 


Thr Phe Asn Arg Cys Glu Glu Val Gln Leu Gln Pro Pro Glu Val Trp 
385                 390                 395                 400 


Ser Pro Asp Pro Cys Gln Pro His Ser His Asp Phe Leu Thr Asp Ala 
                405                 410                 415     


Ile Val Arg Lys Met Ser Arg Met Phe Cys Gln Ala Ala Arg Val Asp 
            420                 425                 430         


Leu Thr Leu Asp Pro Asp Thr Ala His Pro Ala Leu Met Leu Ser Pro 
        435                 440                 445             


Asp Arg Arg Gly Val Arg Leu Ala Glu Arg Arg Gln Glu Val Ala Asp 
    450                 455                 460                 


His Pro Lys Arg Phe Ser Ala Asp Cys Cys Val Leu Gly Ala Gln Gly 
465                 470                 475                 480 


Phe Arg Ser Gly Arg His Tyr Trp Glu Glu Pro Lys Glu Pro Ser Trp 
                485                 490                 495     


Pro Pro Ala Gln Pro Ser Leu Thr Tyr Tyr Val Cys Pro Thr Asp Arg 
            500                 505                 510         


Pro Glu Phe Ser Phe Thr 
        515             


<210>  3508
<211>  868
<212>  PRT
<213>  homo sapiens

<400>  3508

Met Ala Ser Phe Pro Glu Thr Asp Phe Gln Ile Cys Leu Leu Cys Lys 
1               5                   10                  15      


Glu Met Cys Gly Ser Pro Ala Pro Leu Ser Ser Asn Ser Ser Ala Ser 
            20                  25                  30          


Ser Ser Ser Ser Gln Thr Ser Thr Ser Ser Gly Gly Gly Gly Gly Gly 
        35                  40                  45              


Pro Gly Ala Ala Ala Arg Arg Leu His Val Leu Pro Cys Leu His Ala 
    50                  55                  60                  


Phe Cys Arg Pro Cys Leu Glu Ala His Arg Leu Pro Ala Ala Gly Gly 
65                  70                  75                  80  


Gly Ala Ala Gly Glu Pro Leu Lys Leu Arg Cys Pro Val Cys Asp Gln 
                85                  90                  95      


Lys Val Val Leu Ala Glu Ala Ala Gly Met Asp Ala Leu Pro Ser Ser 
            100                 105                 110         


Ala Phe Leu Leu Ser Asn Leu Leu Asp Ala Val Val Ala Thr Ala Asp 
        115                 120                 125             


Glu Pro Pro Pro Lys Asn Gly Arg Ala Gly Ala Pro Ala Gly Ala Gly 
    130                 135                 140                 


Gly His Ser Asn His Arg His His Ala His His Ala His Pro Arg Ala 
145                 150                 155                 160 


Ser Ala Ser Ala Pro Pro Leu Pro Gln Ala Pro Gln Pro Pro Ala Pro 
                165                 170                 175     


Ser Arg Ser Ala Pro Gly Gly Pro Ala Ala Ser Pro Ser Ala Leu Leu 
            180                 185                 190         


Leu Arg Arg Pro His Gly Cys Ser Ser Cys Asp Glu Gly Asn Ala Ala 
        195                 200                 205             


Ser Ser Arg Cys Leu Asp Cys Gln Glu His Leu Cys Asp Asn Cys Val 
    210                 215                 220                 


Arg Ala His Gln Arg Val Arg Leu Thr Lys Asp His Tyr Ile Glu Arg 
225                 230                 235                 240 


Gly Pro Pro Gly Pro Gly Ala Ala Ala Ala Ala Gln Gln Leu Gly Leu 
                245                 250                 255     


Gly Pro Pro Phe Pro Gly Pro Pro Phe Ser Ile Leu Ser Val Phe Pro 
            260                 265                 270         


Glu Arg Leu Gly Phe Cys Gln His His Asp Asp Glu Val Leu His Leu 
        275                 280                 285             


Tyr Cys Asp Thr Cys Ser Val Pro Ile Cys Arg Glu Cys Thr Met Gly 
    290                 295                 300                 


Arg His Gly Gly His Ser Phe Ile Tyr Leu Gln Glu Ala Leu Gln Asp 
305                 310                 315                 320 


Ser Arg Ala Leu Thr Ile Gln Leu Leu Ala Asp Ala Gln Gln Gly Arg 
                325                 330                 335     


Gln Ala Ile Gln Leu Ser Ile Glu Gln Ala Gln Thr Val Ala Glu Gln 
            340                 345                 350         


Val Glu Met Lys Ala Lys Val Val Gln Ser Glu Val Lys Ala Val Thr 
        355                 360                 365             


Ala Arg His Lys Lys Ala Leu Glu Glu Arg Glu Cys Glu Leu Leu Trp 
    370                 375                 380                 


Lys Val Glu Lys Ile Arg Gln Val Lys Ala Lys Ser Leu Tyr Leu Gln 
385                 390                 395                 400 


Val Glu Lys Leu Arg Gln Asn Leu Asn Lys Leu Glu Ser Thr Ile Ser 
                405                 410                 415     


Ala Val Gln Gln Val Leu Glu Glu Gly Arg Ala Leu Asp Ile Leu Leu 
            420                 425                 430         


Ala Arg Asp Arg Met Leu Ala Gln Val Gln Glu Leu Lys Thr Val Arg 
        435                 440                 445             


Ser Leu Leu Gln Pro Gln Glu Asp Asp Arg Val Met Phe Thr Pro Pro 
    450                 455                 460                 


Asp Gln Ala Leu Tyr Leu Ala Ile Lys Ser Phe Gly Phe Val Ser Ser 
465                 470                 475                 480 


Gly Ala Phe Ala Pro Leu Thr Lys Ala Thr Gly Asp Gly Leu Lys Arg 
                485                 490                 495     


Ala Leu Gln Gly Lys Val Ala Ser Phe Thr Val Ile Gly Tyr Asp His 
            500                 505                 510         


Asp Gly Glu Pro Arg Leu Ser Gly Gly Asp Leu Met Ser Ala Val Val 
        515                 520                 525             


Leu Gly Pro Asp Gly Asn Leu Phe Gly Ala Glu Val Ser Asp Gln Gln 
    530                 535                 540                 


Asn Gly Thr Tyr Val Val Ser Tyr Arg Pro Gln Leu Glu Gly Glu His 
545                 550                 555                 560 


Leu Val Ser Val Thr Leu Cys Asn Gln His Ile Glu Asn Ser Pro Phe 
                565                 570                 575     


Lys Val Val Val Lys Ser Gly Arg Ser Tyr Val Gly Ile Gly Leu Pro 
            580                 585                 590         


Gly Leu Ser Phe Gly Ser Glu Gly Asp Ser Asp Gly Lys Leu Cys Arg 
        595                 600                 605             


Pro Trp Gly Val Ser Val Asp Lys Glu Gly Tyr Ile Ile Val Ala Asp 
    610                 615                 620                 


Arg Ser Asn Asn Arg Ile Gln Val Phe Lys Pro Cys Gly Ala Phe His 
625                 630                 635                 640 


His Lys Phe Gly Thr Leu Gly Ser Arg Pro Gly Gln Phe Asp Arg Pro 
                645                 650                 655     


Ala Gly Val Ala Cys Asp Ala Ser Arg Arg Ile Val Val Ala Asp Lys 
            660                 665                 670         


Asp Asn His Arg Ile Gln Ile Phe Thr Phe Glu Gly Gln Phe Leu Leu 
        675                 680                 685             


Lys Phe Gly Glu Lys Gly Thr Lys Asn Gly Gln Phe Asn Tyr Pro Trp 
    690                 695                 700                 


Asp Val Ala Val Asn Ser Glu Gly Lys Ile Leu Val Ser Asp Thr Arg 
705                 710                 715                 720 


Asn His Arg Ile Gln Leu Phe Gly Pro Asp Gly Val Phe Leu Asn Lys 
                725                 730                 735     


Tyr Gly Phe Glu Gly Ala Leu Trp Lys His Phe Asp Ser Pro Arg Gly 
            740                 745                 750         


Val Ala Phe Asn His Glu Gly His Leu Val Val Thr Asp Phe Asn Asn 
        755                 760                 765             


His Arg Leu Leu Val Ile His Pro Asp Cys Gln Ser Ala Arg Phe Leu 
    770                 775                 780                 


Gly Ser Glu Gly Thr Gly Asn Gly Gln Phe Leu Arg Pro Gln Gly Val 
785                 790                 795                 800 


Ala Val Asp Gln Glu Gly Arg Ile Ile Val Ala Asp Ser Arg Asn His 
                805                 810                 815     


Arg Val Gln Met Phe Glu Ser Asn Gly Ser Phe Leu Cys Lys Phe Gly 
            820                 825                 830         


Ala Gln Gly Ser Gly Phe Gly Gln Met Asp Arg Pro Ser Gly Ile Ala 
        835                 840                 845             


Ile Thr Pro Asp Gly Met Ile Val Val Val Asp Phe Gly Asn Asn Arg 
    850                 855                 860                 


Ile Leu Val Phe 
865             


<210>  3509
<211>  606
<212>  PRT
<213>  homo sapiens

<400>  3509

Met Leu Asp Arg Arg Leu Ile Ala Pro Gln Thr Lys Tyr Ile Ile Pro 
1               5                   10                  15      


Gly Gly Ser Ala Asp Ser Tyr Thr Ser Arg Pro Ser Asp Ser Asp Val 
            20                  25                  30          


Ser Leu Glu Glu Asp Arg Glu Ala Val Arg Arg Glu Ala Glu Arg Gln 
        35                  40                  45              


Ala Gln Ala Gln Leu Glu Lys Ala Lys Thr Lys Pro Val Ala Phe Ala 
    50                  55                  60                  


Val Arg Thr Asn Val Ser Tyr Ser Ala Ala His Glu Asp Asp Val Pro 
65                  70                  75                  80  


Val Pro Gly Met Ala Ile Ser Phe Glu Ala Lys Asp Phe Leu His Val 
                85                  90                  95      


Lys Glu Lys Phe Asn Asn Asp Trp Trp Ile Gly Arg Leu Val Lys Glu 
            100                 105                 110         


Gly Cys Glu Ile Gly Phe Ile Pro Ser Pro Val Lys Leu Glu Asn Met 
        115                 120                 125             


Arg Leu Gln His Glu Gln Arg Ala Lys Gln Gly Lys Phe Tyr Ser Ser 
    130                 135                 140                 


Lys Ser Gly Gly Asn Ser Ser Ser Ser Leu Gly Asp Ile Val Pro Ser 
145                 150                 155                 160 


Ser Arg Lys Ser Thr Pro Pro Ser Ser Ala Ile Asp Ile Asp Ala Thr 
                165                 170                 175     


Gly Leu Asp Ala Glu Glu Asn Asp Ile Pro Ala Asn His Arg Ser Pro 
            180                 185                 190         


Lys Pro Ser Ala Asn Ser Val Thr Ser Pro His Ser Lys Glu Lys Arg 
        195                 200                 205             


Met Pro Phe Phe Lys Lys Thr Glu His Thr Pro Pro Tyr Asp Val Val 
    210                 215                 220                 


Pro Ser Met Arg Pro Val Val Leu Val Gly Pro Ser Leu Lys Gly Tyr 
225                 230                 235                 240 


Glu Val Thr Asp Met Met Gln Lys Ala Leu Phe Asp Phe Leu Lys His 
                245                 250                 255     


Arg Phe Glu Gly Arg Ile Ser Ile Thr Arg Val Thr Ala Asp Ile Ser 
            260                 265                 270         


Leu Ala Lys Arg Ser Val Leu Asn Asn Pro Ser Lys His Ala Ile Ile 
        275                 280                 285             


Glu Arg Ser Asn Thr Arg Ser Ser Leu Ala Glu Val Gln Ser Glu Ile 
    290                 295                 300                 


Glu Arg Ile Phe Glu Leu Ala Arg Thr Leu Gln Leu Val Val Leu Asp 
305                 310                 315                 320 


Ala Asp Thr Ile Asn His Pro Ala Gln Leu Ser Lys Thr Ser Leu Ala 
                325                 330                 335     


Pro Ile Ile Val Tyr Val Lys Ile Ser Ser Pro Lys Val Leu Gln Arg 
            340                 345                 350         


Leu Ile Lys Ser Arg Gly Lys Ser Gln Ala Lys His Leu Asn Val Gln 
        355                 360                 365             


Met Val Ala Ala Asp Lys Leu Ala Gln Cys Pro Pro Glu Leu Phe Asp 
    370                 375                 380                 


Val Ile Leu Asp Glu Asn Gln Leu Glu Asp Ala Cys Glu His Leu Ala 
385                 390                 395                 400 


Asp Tyr Leu Glu Ala Tyr Trp Lys Ala Thr His Pro Pro Ser Ser Ser 
                405                 410                 415     


Leu Pro Asn Pro Leu Leu Ser Arg Thr Leu Ala Thr Ser Ser Leu Pro 
            420                 425                 430         


Leu Ser Pro Thr Leu Ala Ser Asn Ser Gln Gly Ser Gln Gly Asp Gln 
        435                 440                 445             


Arg Thr Asp Arg Ser Ala Pro Ile Arg Ser Ala Ser Gln Ala Glu Glu 
    450                 455                 460                 


Glu Pro Ser Val Glu Pro Val Lys Lys Ser Gln His Arg Ser Ser Ser 
465                 470                 475                 480 


Ser Ala Pro His His Asn His Arg Ser Gly Thr Ser Arg Gly Leu Ser 
                485                 490                 495     


Arg Gln Glu Thr Phe Asp Ser Glu Thr Gln Glu Ser Arg Asp Ser Ala 
            500                 505                 510         


Tyr Val Glu Pro Lys Glu Asp Tyr Ser His Asp His Val Asp His Tyr 
        515                 520                 525             


Ala Ser His Arg Asp His Asn His Arg Asp Glu Thr His Gly Ser Ser 
    530                 535                 540                 


Asp His Arg His Arg Glu Ser Arg His Arg Ser Arg Asp Val Asp Arg 
545                 550                 555                 560 


Glu Gln Asp His Asn Glu Cys Asn Lys Gln Arg Ser Arg His Lys Ser 
                565                 570                 575     


Lys Asp Arg Tyr Cys Glu Lys Asp Gly Glu Val Ile Ser Lys Lys Arg 
            580                 585                 590         


Asn Glu Ala Gly Glu Trp Asn Arg Asp Val Tyr Ile Arg Gln 
        595                 600                 605     


<210>  3510
<211>  462
<212>  PRT
<213>  homo sapiens

<400>  3510

Met Asp Thr Lys His Phe Leu Pro Leu Asp Phe Ser Thr Gln Val Asn 
1               5                   10                  15      


Ser Ser Leu Thr Ser Pro Thr Gly Arg Gly Ser Met Ala Ala Pro Ser 
            20                  25                  30          


Leu His Pro Ser Leu Gly Pro Gly Ile Gly Ser Pro Gly Gln Leu His 
        35                  40                  45              


Ser Pro Ile Ser Thr Leu Ser Ser Pro Ile Asn Gly Met Gly Pro Pro 
    50                  55                  60                  


Phe Ser Val Ile Ser Ser Pro Met Gly Pro His Ser Met Ser Val Pro 
65                  70                  75                  80  


Thr Thr Pro Thr Leu Gly Phe Ser Thr Gly Ser Pro Gln Leu Ser Ser 
                85                  90                  95      


Pro Met Asn Pro Val Ser Ser Ser Glu Asp Ile Lys Pro Pro Leu Gly 
            100                 105                 110         


Leu Asn Gly Val Leu Lys Val Pro Ala His Pro Ser Gly Asn Met Ala 
        115                 120                 125             


Ser Phe Thr Lys His Ile Cys Ala Ile Cys Gly Asp Arg Ser Ser Gly 
    130                 135                 140                 


Lys His Tyr Gly Val Tyr Ser Cys Glu Gly Cys Lys Gly Phe Phe Lys 
145                 150                 155                 160 


Arg Thr Val Arg Lys Asp Leu Thr Tyr Thr Cys Arg Asp Asn Lys Asp 
                165                 170                 175     


Cys Leu Ile Asp Lys Arg Gln Arg Asn Arg Cys Gln Tyr Cys Arg Tyr 
            180                 185                 190         


Gln Lys Cys Leu Ala Met Gly Met Lys Arg Glu Ala Val Gln Glu Glu 
        195                 200                 205             


Arg Gln Arg Gly Lys Asp Arg Asn Glu Asn Glu Val Glu Ser Thr Ser 
    210                 215                 220                 


Ser Ala Asn Glu Asp Met Pro Val Glu Arg Ile Leu Glu Ala Glu Leu 
225                 230                 235                 240 


Ala Val Glu Pro Lys Thr Glu Thr Tyr Val Glu Ala Asn Met Gly Leu 
                245                 250                 255     


Asn Pro Ser Ser Pro Asn Asp Pro Val Thr Asn Ile Cys Gln Ala Ala 
            260                 265                 270         


Asp Lys Gln Leu Phe Thr Leu Val Glu Trp Ala Lys Arg Ile Pro His 
        275                 280                 285             


Phe Ser Glu Leu Pro Leu Asp Asp Gln Val Ile Leu Leu Arg Ala Gly 
    290                 295                 300                 


Trp Asn Glu Leu Leu Ile Ala Ser Phe Ser His Arg Ser Ile Ala Val 
305                 310                 315                 320 


Lys Asp Gly Ile Leu Leu Ala Thr Gly Leu His Val His Arg Asn Ser 
                325                 330                 335     


Ala His Ser Ala Gly Val Gly Ala Ile Phe Asp Arg Val Leu Thr Glu 
            340                 345                 350         


Leu Val Ser Lys Met Arg Asp Met Gln Met Asp Lys Thr Glu Leu Gly 
        355                 360                 365             


Cys Leu Arg Ala Ile Val Leu Phe Asn Pro Asp Ser Lys Gly Leu Ser 
    370                 375                 380                 


Asn Pro Ala Glu Val Glu Ala Leu Arg Glu Lys Val Tyr Ala Ser Leu 
385                 390                 395                 400 


Glu Ala Tyr Cys Lys His Lys Tyr Pro Glu Gln Pro Gly Arg Phe Ala 
                405                 410                 415     


Lys Leu Leu Leu Arg Leu Pro Ala Leu Arg Ser Ile Gly Leu Lys Cys 
            420                 425                 430         


Leu Glu His Leu Phe Phe Phe Lys Leu Ile Gly Asp Thr Pro Ile Asp 
        435                 440                 445             


Thr Phe Leu Met Glu Met Leu Glu Ala Pro His Gln Met Thr 
    450                 455                 460         


<210>  3511
<211>  1690
<212>  PRT
<213>  homo sapiens

<400>  3511

Met Glu Pro Trp Ser Ser Arg Trp Lys Thr Lys Arg Trp Leu Trp Asp 
1               5                   10                  15      


Phe Thr Val Thr Thr Leu Ala Leu Thr Phe Leu Phe Gln Ala Arg Glu 
            20                  25                  30          


Val Arg Gly Ala Ala Pro Val Asp Val Leu Lys Ala Leu Asp Phe His 
        35                  40                  45              


Asn Ser Pro Glu Gly Ile Ser Lys Thr Thr Gly Phe Cys Thr Asn Arg 
    50                  55                  60                  


Lys Asn Ser Lys Gly Ser Asp Thr Ala Tyr Arg Val Ser Lys Gln Ala 
65                  70                  75                  80  


Gln Leu Ser Ala Pro Thr Lys Gln Leu Phe Pro Gly Gly Thr Phe Pro 
                85                  90                  95      


Glu Asp Phe Ser Ile Leu Phe Thr Val Lys Pro Lys Lys Gly Ile Gln 
            100                 105                 110         


Ser Phe Leu Leu Ser Ile Tyr Asn Glu His Gly Ile Gln Gln Ile Gly 
        115                 120                 125             


Val Glu Val Gly Arg Ser Pro Val Phe Leu Phe Glu Asp His Thr Gly 
    130                 135                 140                 


Lys Pro Ala Pro Glu Asp Tyr Pro Leu Phe Arg Thr Val Asn Ile Ala 
145                 150                 155                 160 


Asp Gly Lys Trp His Arg Val Ala Ile Ser Val Glu Lys Lys Thr Val 
                165                 170                 175     


Thr Met Ile Val Asp Cys Lys Lys Lys Thr Thr Lys Pro Leu Asp Arg 
            180                 185                 190         


Ser Glu Arg Ala Ile Val Asp Thr Asn Gly Ile Thr Val Phe Gly Thr 
        195                 200                 205             


Arg Ile Leu Asp Glu Glu Val Phe Glu Gly Asp Ile Gln Gln Phe Leu 
    210                 215                 220                 


Ile Thr Gly Asp Pro Lys Ala Ala Tyr Asp Tyr Cys Glu His Tyr Ser 
225                 230                 235                 240 


Pro Asp Cys Asp Ser Ser Ala Pro Lys Ala Ala Gln Ala Gln Glu Pro 
                245                 250                 255     


Gln Ile Asp Glu Tyr Ala Pro Glu Asp Ile Ile Glu Tyr Asp Tyr Glu 
            260                 265                 270         


Tyr Gly Glu Ala Glu Tyr Lys Glu Ala Glu Ser Val Thr Glu Gly Pro 
        275                 280                 285             


Thr Val Thr Glu Glu Thr Ile Ala Gln Thr Glu Ile Asn Gly His Gly 
    290                 295                 300                 


Ala Tyr Gly Glu Lys Gly Gln Lys Gly Glu Pro Ala Val Val Glu Pro 
305                 310                 315                 320 


Gly Met Leu Val Glu Gly Pro Pro Gly Pro Ala Gly Pro Ala Gly Ile 
                325                 330                 335     


Met Gly Pro Pro Gly Leu Gln Gly Pro Thr Gly Pro Pro Gly Asp Pro 
            340                 345                 350         


Gly Asp Arg Gly Pro Pro Gly Arg Pro Gly Leu Pro Gly Ala Asp Gly 
        355                 360                 365             


Leu Pro Gly Pro Pro Gly Thr Met Leu Met Leu Pro Phe Arg Tyr Gly 
    370                 375                 380                 


Gly Asp Gly Ser Lys Gly Pro Thr Ile Ser Ala Gln Glu Ala Gln Ala 
385                 390                 395                 400 


Gln Ala Ile Leu Gln Gln Ala Arg Ile Ala Leu Arg Gly Pro Pro Gly 
                405                 410                 415     


Pro Met Gly Leu Thr Gly Arg Pro Gly Pro Val Gly Gly Pro Gly Ser 
            420                 425                 430         


Ser Gly Ala Lys Gly Glu Ser Gly Asp Pro Gly Pro Gln Gly Pro Arg 
        435                 440                 445             


Gly Val Gln Gly Pro Pro Gly Pro Thr Gly Lys Pro Gly Lys Arg Gly 
    450                 455                 460                 


Arg Pro Gly Ala Asp Gly Gly Arg Gly Met Pro Gly Glu Pro Gly Ala 
465                 470                 475                 480 


Lys Gly Asp Arg Gly Phe Asp Gly Leu Pro Gly Leu Pro Gly Asp Lys 
                485                 490                 495     


Gly His Arg Gly Glu Arg Gly Pro Gln Gly Pro Pro Gly Pro Pro Gly 
            500                 505                 510         


Asp Asp Gly Met Arg Gly Glu Asp Gly Glu Ile Gly Pro Arg Gly Leu 
        515                 520                 525             


Pro Gly Glu Ala Gly Pro Arg Gly Leu Leu Gly Pro Arg Gly Thr Pro 
    530                 535                 540                 


Gly Ala Pro Gly Gln Pro Gly Met Ala Gly Val Asp Gly Pro Pro Gly 
545                 550                 555                 560 


Pro Lys Gly Asn Met Gly Pro Gln Gly Glu Pro Gly Pro Pro Gly Gln 
                565                 570                 575     


Gln Gly Asn Pro Gly Pro Gln Gly Leu Pro Gly Pro Gln Gly Pro Ile 
            580                 585                 590         


Gly Pro Pro Gly Glu Lys Gly Pro Gln Gly Lys Pro Gly Leu Ala Gly 
        595                 600                 605             


Leu Pro Gly Ala Asp Gly Pro Pro Gly His Pro Gly Lys Glu Gly Gln 
    610                 615                 620                 


Ser Gly Glu Lys Gly Ala Leu Gly Pro Pro Gly Pro Gln Gly Pro Ile 
625                 630                 635                 640 


Gly Tyr Pro Gly Pro Arg Gly Val Lys Gly Ala Asp Gly Val Arg Gly 
                645                 650                 655     


Leu Lys Gly Ser Lys Gly Glu Lys Gly Glu Asp Gly Phe Pro Gly Phe 
            660                 665                 670         


Lys Gly Asp Met Gly Leu Lys Gly Asp Arg Gly Glu Val Gly Gln Ile 
        675                 680                 685             


Gly Pro Arg Gly Glu Asp Gly Pro Glu Gly Pro Lys Gly Arg Ala Gly 
    690                 695                 700                 


Pro Thr Gly Asp Pro Gly Pro Ser Gly Gln Ala Gly Glu Lys Gly Lys 
705                 710                 715                 720 


Leu Gly Val Pro Gly Leu Pro Gly Tyr Pro Gly Arg Gln Gly Pro Lys 
                725                 730                 735     


Gly Ser Thr Gly Phe Pro Gly Phe Pro Gly Ala Asn Gly Glu Lys Gly 
            740                 745                 750         


Ala Arg Gly Val Ala Gly Lys Pro Gly Pro Arg Gly Gln Arg Gly Pro 
        755                 760                 765             


Thr Gly Pro Arg Gly Ser Arg Gly Ala Arg Gly Pro Thr Gly Lys Pro 
    770                 775                 780                 


Gly Pro Lys Gly Thr Ser Gly Gly Asp Gly Pro Pro Gly Pro Pro Gly 
785                 790                 795                 800 


Glu Arg Gly Pro Gln Gly Pro Gln Gly Pro Val Gly Phe Pro Gly Pro 
                805                 810                 815     


Lys Gly Pro Pro Gly Pro Pro Gly Lys Asp Gly Leu Pro Gly His Pro 
            820                 825                 830         


Gly Gln Arg Gly Glu Thr Gly Phe Gln Gly Lys Thr Gly Pro Pro Gly 
        835                 840                 845             


Pro Gly Gly Val Val Gly Pro Gln Gly Pro Thr Gly Glu Thr Gly Pro 
    850                 855                 860                 


Ile Gly Glu Arg Gly His Pro Gly Pro Pro Gly Pro Pro Gly Glu Gln 
865                 870                 875                 880 


Gly Leu Pro Gly Ala Ala Gly Lys Glu Gly Ala Lys Gly Asp Pro Gly 
                885                 890                 895     


Pro Gln Gly Ile Ser Gly Lys Asp Gly Pro Ala Gly Leu Arg Gly Phe 
            900                 905                 910         


Pro Gly Glu Arg Gly Leu Pro Gly Ala Gln Gly Ala Pro Gly Leu Lys 
        915                 920                 925             


Gly Gly Glu Gly Pro Gln Gly Pro Pro Gly Pro Val Gly Ser Pro Gly 
    930                 935                 940                 


Glu Arg Gly Ser Ala Gly Thr Ala Gly Pro Ile Gly Leu Pro Gly Arg 
945                 950                 955                 960 


Pro Gly Pro Gln Gly Pro Pro Gly Pro Ala Gly Glu Lys Gly Ala Pro 
                965                 970                 975     


Gly Glu Lys Gly Pro Gln Gly Pro Ala Gly Arg Asp Gly Val Gln Gly 
            980                 985                 990         


Pro Val Gly Leu Pro Gly Pro Ala  Gly Pro Ala Gly Ser  Pro Gly Glu 
        995                 1000                 1005             


Asp Gly  Asp Lys Gly Glu Ile  Gly Glu Pro Gly Gln  Lys Gly Ser 
    1010                 1015                 1020             


Lys Gly  Asp Lys Gly Glu Asn  Gly Pro Pro Gly Pro  Pro Gly Leu 
    1025                 1030                 1035             


Gln Gly  Pro Val Gly Ala Pro  Gly Ile Ala Gly Gly  Asp Gly Glu 
    1040                 1045                 1050             


Pro Gly  Pro Arg Gly Gln Gln  Gly Met Phe Gly Gln  Lys Gly Asp 
    1055                 1060                 1065             


Glu Gly  Ala Arg Gly Phe Pro  Gly Pro Pro Gly Pro  Ile Gly Leu 
    1070                 1075                 1080             


Gln Gly  Leu Pro Gly Pro Pro  Gly Glu Lys Gly Glu  Asn Gly Asp 
    1085                 1090                 1095             


Val Gly  Pro Met Gly Pro Pro  Gly Pro Pro Gly Pro  Arg Gly Pro 
    1100                 1105                 1110             


Gln Gly  Pro Asn Gly Ala Asp  Gly Pro Gln Gly Pro  Pro Gly Ser 
    1115                 1120                 1125             


Val Gly  Ser Val Gly Gly Val  Gly Glu Lys Gly Glu  Pro Gly Glu 
    1130                 1135                 1140             


Ala Gly  Asn Pro Gly Pro Pro  Gly Glu Ala Gly Val  Gly Gly Pro 
    1145                 1150                 1155             


Lys Gly  Glu Arg Gly Glu Lys  Gly Glu Ala Gly Pro  Pro Gly Ala 
    1160                 1165                 1170             


Ala Gly  Pro Pro Gly Ala Lys  Gly Pro Pro Gly Asp  Asp Gly Pro 
    1175                 1180                 1185             


Lys Gly  Asn Pro Gly Pro Val  Gly Phe Pro Gly Asp  Pro Gly Pro 
    1190                 1195                 1200             


Pro Gly  Glu Pro Gly Pro Ala  Gly Gln Asp Gly Val  Gly Gly Asp 
    1205                 1210                 1215             


Lys Gly  Glu Asp Gly Asp Pro  Gly Gln Pro Gly Pro  Pro Gly Pro 
    1220                 1225                 1230             


Ser Gly  Glu Ala Gly Pro Pro  Gly Pro Pro Gly Lys  Arg Gly Pro 
    1235                 1240                 1245             


Pro Gly  Ala Ala Gly Ala Glu  Gly Arg Gln Gly Glu  Lys Gly Ala 
    1250                 1255                 1260             


Lys Gly  Glu Ala Gly Ala Glu  Gly Pro Pro Gly Lys  Thr Gly Pro 
    1265                 1270                 1275             


Val Gly  Pro Gln Gly Pro Ala  Gly Lys Pro Gly Pro  Glu Gly Leu 
    1280                 1285                 1290             


Arg Gly  Ile Pro Gly Pro Val  Gly Glu Gln Gly Leu  Pro Gly Ala 
    1295                 1300                 1305             


Ala Gly  Gln Asp Gly Pro Pro  Gly Pro Met Gly Pro  Pro Gly Leu 
    1310                 1315                 1320             


Pro Gly  Leu Lys Gly Asp Pro  Gly Ser Lys Gly Glu  Lys Gly His 
    1325                 1330                 1335             


Pro Gly  Leu Ile Gly Leu Ile  Gly Pro Pro Gly Glu  Gln Gly Glu 
    1340                 1345                 1350             


Lys Gly  Asp Arg Gly Leu Pro  Gly Thr Gln Gly Ser  Pro Gly Ala 
    1355                 1360                 1365             


Lys Gly  Asp Gly Gly Ile Pro  Gly Pro Ala Gly Pro  Leu Gly Pro 
    1370                 1375                 1380             


Pro Gly  Pro Pro Gly Leu Pro  Gly Pro Gln Gly Pro  Lys Gly Asn 
    1385                 1390                 1395             


Lys Gly  Ser Thr Gly Pro Ala  Gly Gln Lys Gly Asp  Ser Gly Leu 
    1400                 1405                 1410             


Pro Gly  Pro Pro Gly Ser Pro  Gly Pro Pro Gly Glu  Val Ile Gln 
    1415                 1420                 1425             


Pro Leu  Pro Ile Leu Ser Ser  Lys Lys Thr Arg Arg  His Thr Glu 
    1430                 1435                 1440             


Gly Met  Gln Ala Asp Ala Asp  Asp Asn Ile Leu Asp  Tyr Ser Asp 
    1445                 1450                 1455             


Gly Met  Glu Glu Ile Phe Gly  Ser Leu Asn Ser Leu  Lys Gln Asp 
    1460                 1465                 1470             


Ile Glu  His Met Lys Phe Pro  Met Gly Thr Gln Thr  Asn Pro Ala 
    1475                 1480                 1485             


Arg Thr  Cys Lys Asp Leu Gln  Leu Ser His Pro Asp  Phe Pro Asp 
    1490                 1495                 1500             


Gly Glu  Tyr Trp Ile Asp Pro  Asn Gln Gly Cys Ser  Gly Asp Ser 
    1505                 1510                 1515             


Phe Lys  Val Tyr Cys Asn Phe  Thr Ser Gly Gly Glu  Thr Cys Ile 
    1520                 1525                 1530             


Tyr Pro  Asp Lys Lys Ser Glu  Gly Val Arg Ile Ser  Ser Trp Pro 
    1535                 1540                 1545             


Lys Glu  Lys Pro Gly Ser Trp  Phe Ser Glu Phe Lys  Arg Gly Lys 
    1550                 1555                 1560             


Leu Leu  Ser Tyr Leu Asp Val  Glu Gly Asn Ser Ile  Asn Met Val 
    1565                 1570                 1575             


Gln Met  Thr Phe Leu Lys Leu  Leu Thr Ala Ser Ala  Arg Gln Asn 
    1580                 1585                 1590             


Phe Thr  Tyr His Cys His Gln  Ser Ala Ala Trp Tyr  Asp Val Ser 
    1595                 1600                 1605             


Ser Gly  Ser Tyr Asp Lys Ala  Leu Arg Phe Leu Gly  Ser Asn Asp 
    1610                 1615                 1620             


Glu Glu  Met Ser Tyr Asp Asn  Asn Pro Phe Ile Lys  Thr Leu Tyr 
    1625                 1630                 1635             


Asp Gly  Cys Ala Ser Arg Lys  Gly Tyr Glu Lys Thr  Val Ile Glu 
    1640                 1645                 1650             


Ile Asn  Thr Pro Lys Ile Asp  Gln Val Pro Ile Val  Asp Val Met 
    1655                 1660                 1665             


Ile Asn  Asp Phe Gly Asp Gln  Asn Gln Lys Phe Gly  Phe Glu Val 
    1670                 1675                 1680             


Gly Pro  Val Cys Phe Leu Gly  
    1685                 1690 


<210>  3512
<211>  377
<212>  PRT
<213>  homo sapiens

<400>  3512

Met His Asp Glu Val Ala Gln Pro Leu Asn Leu Ser Ala Lys Pro Lys 
1               5                   10                  15      


Thr Ser Asp Gly Lys Ser Pro Thr Ser Pro Thr Ser Pro His Met Pro 
            20                  25                  30          


Ala Leu Arg Ile Asn Ser Gly Ala Gly Pro Leu Lys Ala Ser Val Pro 
        35                  40                  45              


Ala Ala Leu Ala Ser Pro Ser Ala Arg Val Ser Thr Ile Gly Tyr Leu 
    50                  55                  60                  


Asn Asp His Asp Ala Val Thr Lys Ala Ile Gln Glu Ala Arg Gln Met 
65                  70                  75                  80  


Lys Glu Gln Leu Arg Arg Glu Gln Gln Val Leu Asp Gly Lys Val Ala 
                85                  90                  95      


Val Val Asn Ser Leu Gly Leu Asn Asn Cys Arg Thr Glu Lys Glu Lys 
            100                 105                 110         


Thr Thr Leu Glu Ser Leu Thr Gln Gln Leu Ala Val Lys Gln Asn Glu 
        115                 120                 125             


Glu Gly Lys Phe Ser His Ala Met Met Asp Phe Asn Leu Ser Gly Asp 
    130                 135                 140                 


Ser Asp Gly Ser Ala Gly Val Ser Glu Ser Arg Ile Tyr Arg Glu Ser 
145                 150                 155                 160 


Arg Gly Arg Gly Ser Asn Glu Pro His Ile Lys Arg Pro Met Asn Ala 
                165                 170                 175     


Phe Met Val Trp Ala Lys Asp Glu Arg Arg Lys Ile Leu Gln Ala Phe 
            180                 185                 190         


Pro Asp Met His Asn Ser Asn Ile Ser Lys Ile Leu Gly Ser Arg Trp 
        195                 200                 205             


Lys Ala Met Thr Asn Leu Glu Lys Gln Pro Tyr Tyr Glu Glu Gln Ala 
    210                 215                 220                 


Arg Leu Ser Lys Gln His Leu Glu Lys Tyr Pro Asp Tyr Lys Tyr Lys 
225                 230                 235                 240 


Pro Arg Pro Lys Arg Thr Cys Leu Val Asp Gly Lys Lys Leu Arg Ile 
                245                 250                 255     


Gly Glu Tyr Lys Ala Ile Met Arg Asn Arg Arg Gln Glu Met Arg Gln 
            260                 265                 270         


Tyr Phe Asn Val Gly Gln Gln Ala Gln Ile Pro Ile Ala Thr Ala Gly 
        275                 280                 285             


Val Val Tyr Pro Gly Ala Ile Ala Met Ala Gly Met Pro Ser Pro His 
    290                 295                 300                 


Leu Pro Ser Glu His Ser Ser Val Ser Ser Ser Pro Glu Pro Gly Met 
305                 310                 315                 320 


Pro Val Ile Gln Ser Thr Tyr Gly Val Lys Gly Glu Glu Pro His Ile 
                325                 330                 335     


Lys Glu Glu Ile Gln Ala Glu Asp Ile Asn Gly Glu Ile Tyr Asp Glu 
            340                 345                 350         


Tyr Asp Glu Glu Glu Asp Asp Pro Asp Val Asp Tyr Gly Ser Asp Ser 
        355                 360                 365             


Glu Asn His Ile Ala Gly Gln Ala Asn 
    370                 375         


<210>  3513
<211>  804
<212>  PRT
<213>  homo sapiens

<400>  3513

Met Gly Arg Met Ser Ser Lys Gln Ala Thr Ser Pro Phe Ala Cys Ala 
1               5                   10                  15      


Ala Asp Gly Glu Asp Ala Met Thr Gln Asp Leu Thr Ser Arg Glu Lys 
            20                  25                  30          


Glu Glu Gly Ser Asp Gln His Val Ala Ser His Leu Pro Leu His Pro 
        35                  40                  45              


Ile Met His Asn Lys Pro His Ser Glu Glu Leu Pro Thr Leu Val Ser 
    50                  55                  60                  


Thr Ile Gln Gln Asp Ala Asp Trp Asp Ser Val Leu Ser Ser Gln Gln 
65                  70                  75                  80  


Arg Met Glu Ser Glu Asn Asn Lys Leu Cys Ser Leu Tyr Ser Phe Arg 
                85                  90                  95      


Asn Thr Ser Thr Ser Pro His Lys Pro Asp Glu Gly Ser Arg Asp Arg 
            100                 105                 110         


Glu Ile Met Thr Ser Val Thr Phe Gly Thr Pro Glu Arg Arg Lys Gly 
        115                 120                 125             


Ser Leu Ala Asp Val Val Asp Thr Leu Lys Gln Lys Lys Leu Glu Glu 
    130                 135                 140                 


Met Thr Arg Thr Glu Gln Glu Asp Ser Ser Cys Met Glu Lys Leu Leu 
145                 150                 155                 160 


Ser Lys Asp Trp Lys Glu Lys Met Glu Arg Leu Asn Thr Ser Glu Leu 
                165                 170                 175     


Leu Gly Glu Ile Lys Gly Thr Pro Glu Ser Leu Ala Glu Lys Glu Arg 
            180                 185                 190         


Gln Leu Ser Thr Met Ile Thr Gln Leu Ile Ser Leu Arg Glu Gln Leu 
        195                 200                 205             


Leu Ala Ala His Asp Glu Gln Lys Lys Leu Ala Ala Ser Gln Ile Glu 
    210                 215                 220                 


Lys Gln Arg Gln Gln Met Asp Leu Ala Arg Gln Gln Gln Glu Gln Ile 
225                 230                 235                 240 


Ala Arg Gln Gln Gln Gln Leu Leu Gln Gln Gln His Lys Ile Asn Leu 
                245                 250                 255     


Leu Gln Gln Gln Ile Gln Val Gln Gly His Met Pro Pro Leu Met Ile 
            260                 265                 270         


Pro Ile Phe Pro His Asp Gln Arg Thr Leu Ala Ala Ala Ala Ala Ala 
        275                 280                 285             


Gln Gln Gly Phe Leu Phe Pro Pro Gly Ile Thr Tyr Lys Pro Gly Asp 
    290                 295                 300                 


Asn Tyr Pro Val Gln Phe Ile Pro Ser Thr Met Ala Ala Ala Ala Ala 
305                 310                 315                 320 


Ser Gly Leu Ser Pro Leu Gln Leu Gln Gln Leu Tyr Ala Ala Gln Leu 
                325                 330                 335     


Ala Ser Met Gln Val Ser Pro Gly Ala Lys Met Pro Ser Thr Pro Gln 
            340                 345                 350         


Pro Pro Asn Thr Ala Gly Thr Val Ser Pro Thr Gly Ile Lys Asn Glu 
        355                 360                 365             


Lys Arg Gly Thr Ser Pro Val Thr Gln Val Lys Asp Glu Ala Ala Ala 
    370                 375                 380                 


Gln Pro Leu Asn Leu Ser Ser Arg Pro Lys Thr Ala Glu Pro Val Lys 
385                 390                 395                 400 


Ser Pro Thr Ser Pro Thr Gln Asn Leu Phe Pro Ala Ser Lys Thr Ser 
                405                 410                 415     


Pro Val Asn Leu Pro Asn Lys Ser Ser Ile Pro Ser Pro Ile Gly Gly 
            420                 425                 430         


Ser Leu Gly Arg Gly Ser Ser Leu Gly Lys Trp Lys Ser Gln His Gln 
        435                 440                 445             


Glu Glu Thr Tyr Glu Leu Asp Ile Leu Ser Ser Leu Asn Ser Pro Ala 
    450                 455                 460                 


Leu Phe Gly Asp Gln Asp Thr Val Met Lys Ala Ile Gln Glu Ala Arg 
465                 470                 475                 480 


Lys Met Arg Glu Gln Ile Gln Arg Glu Gln Gln Gln Gln Gln Pro His 
                485                 490                 495     


Gly Val Asp Gly Lys Leu Ser Ser Ile Asn Asn Met Gly Leu Asn Ser 
            500                 505                 510         


Cys Arg Asn Glu Lys Glu Arg Thr Arg Phe Glu Asn Leu Gly Pro Gln 
        515                 520                 525             


Leu Thr Gly Lys Ser Asn Glu Asp Gly Lys Leu Gly Pro Gly Val Ile 
    530                 535                 540                 


Asp Leu Thr Arg Pro Glu Asp Ala Glu Gly Ser Lys Ala Met Asn Gly 
545                 550                 555                 560 


Ser Ala Ala Lys Leu Gln Gln Tyr Tyr Cys Trp Pro Thr Gly Gly Ala 
                565                 570                 575     


Thr Val Ala Glu Ala Arg Val Tyr Arg Asp Ala Arg Gly Arg Ala Ser 
            580                 585                 590         


Ser Glu Pro His Ile Lys Arg Pro Met Asn Ala Phe Met Val Trp Ala 
        595                 600                 605             


Lys Asp Glu Arg Arg Lys Ile Leu Gln Ala Phe Pro Asp Met His Asn 
    610                 615                 620                 


Ser Asn Ile Ser Lys Ile Leu Gly Ser Arg Trp Lys Ser Met Ser Asn 
625                 630                 635                 640 


Gln Glu Lys Gln Pro Tyr Tyr Glu Glu Gln Ala Arg Leu Ser Lys Ile 
                645                 650                 655     


His Leu Glu Lys Tyr Pro Asn Tyr Lys Tyr Lys Pro Arg Pro Lys Arg 
            660                 665                 670         


Thr Cys Ile Val Asp Gly Lys Lys Leu Arg Ile Gly Glu Tyr Lys Gln 
        675                 680                 685             


Leu Met Arg Ser Arg Arg Gln Glu Met Arg Gln Phe Phe Thr Val Gly 
    690                 695                 700                 


Gln Gln Pro Gln Ile Pro Ile Thr Thr Gly Thr Gly Val Val Tyr Pro 
705                 710                 715                 720 


Gly Ala Ile Thr Met Ala Thr Thr Thr Pro Ser Pro Gln Met Thr Ser 
                725                 730                 735     


Asp Cys Ser Ser Thr Ser Ala Ser Pro Glu Pro Ser Leu Pro Val Ile 
            740                 745                 750         


Gln Ser Thr Tyr Gly Met Lys Thr Asp Gly Gly Ser Leu Ala Gly Asn 
        755                 760                 765             


Glu Met Ile Asn Gly Glu Asp Glu Met Glu Met Tyr Asp Asp Tyr Glu 
    770                 775                 780                 


Asp Asp Pro Lys Ser Asp Tyr Ser Ser Glu Asn Glu Ala Pro Glu Ala 
785                 790                 795                 800 


Val Ser Ala Asn 
                


<210>  3514
<211>  808
<212>  PRT
<213>  homo sapiens

<400>  3514

Met Ser Ser Lys Gln Ala Thr Ser Pro Phe Ala Cys Ala Ala Asp Gly 
1               5                   10                  15      


Glu Asp Ala Met Thr Gln Asp Leu Thr Ser Arg Glu Lys Glu Glu Gly 
            20                  25                  30          


Ser Asp Gln His Val Ala Ser His Leu Pro Leu His Pro Ile Met His 
        35                  40                  45              


Asn Lys Pro His Ser Glu Glu Leu Pro Thr Leu Val Ser Thr Ile Gln 
    50                  55                  60                  


Gln Asp Ala Asp Trp Asp Ser Val Leu Ser Ser Gln Gln Arg Met Glu 
65                  70                  75                  80  


Ser Glu Asn Asn Lys Leu Cys Ser Leu Tyr Ser Phe Arg Asn Thr Ser 
                85                  90                  95      


Thr Ser Pro His Lys Pro Asp Glu Gly Ser Arg Asp Arg Glu Ile Met 
            100                 105                 110         


Thr Ser Val Thr Phe Gly Thr Pro Glu Arg Arg Lys Gly Ser Leu Ala 
        115                 120                 125             


Asp Val Val Asp Thr Leu Lys Gln Lys Lys Leu Glu Glu Met Thr Arg 
    130                 135                 140                 


Thr Glu Gln Glu Asp Ser Ser Cys Met Glu Lys Leu Leu Ser Lys Asp 
145                 150                 155                 160 


Trp Lys Glu Lys Met Glu Arg Leu Asn Thr Ser Glu Leu Leu Gly Glu 
                165                 170                 175     


Ile Lys Gly Thr Pro Glu Ser Leu Ala Glu Lys Glu Arg Gln Leu Ser 
            180                 185                 190         


Thr Met Ile Thr Gln Leu Ile Ser Leu Arg Glu Gln Leu Leu Ala Ala 
        195                 200                 205             


His Asp Glu Gln Lys Lys Leu Ala Ala Ser Gln Ile Glu Lys Gln Arg 
    210                 215                 220                 


Gln Gln Met Asp Leu Ala Arg Gln Gln Gln Glu Gln Ile Ala Arg Gln 
225                 230                 235                 240 


Gln Gln Gln Leu Leu Gln Gln Gln His Lys Ile Asn Leu Leu Gln Gln 
                245                 250                 255     


Gln Ile Gln Val Gln Gly His Met Pro Pro Leu Met Ile Pro Ile Phe 
            260                 265                 270         


Pro His Asp Gln Arg Thr Leu Ala Ala Ala Ala Ala Ala Gln Gln Gly 
        275                 280                 285             


Phe Leu Phe Pro Pro Gly Ile Thr Tyr Lys Pro Gly Asp Asn Tyr Pro 
    290                 295                 300                 


Val Gln Phe Ile Pro Ser Thr Met Ala Ala Ala Ala Ala Ser Gly Leu 
305                 310                 315                 320 


Ser Pro Leu Gln Leu Gln Lys Gly His Val Ser His Pro Gln Ile Asn 
                325                 330                 335     


Gln Arg Leu Lys Gly Leu Ser Asp Arg Phe Gly Arg Asn Leu Asp Thr 
            340                 345                 350         


Phe Glu His Gly Gly Gly His Ser Tyr Asn His Lys Gln Ile Glu Gln 
        355                 360                 365             


Leu Tyr Ala Ala Gln Leu Ala Ser Met Gln Val Ser Pro Gly Ala Lys 
    370                 375                 380                 


Met Pro Ser Thr Pro Gln Pro Pro Asn Thr Ala Gly Thr Val Ser Pro 
385                 390                 395                 400 


Thr Gly Ile Lys Asn Glu Lys Arg Gly Thr Ser Pro Val Thr Gln Val 
                405                 410                 415     


Lys Asp Glu Ala Ala Ala Gln Pro Leu Asn Leu Ser Ser Arg Pro Lys 
            420                 425                 430         


Thr Ala Glu Pro Val Lys Ser Pro Thr Ser Pro Thr Gln Asn Leu Phe 
        435                 440                 445             


Pro Ala Ser Lys Thr Ser Pro Val Asn Leu Pro Asn Lys Ser Ser Ile 
    450                 455                 460                 


Pro Ser Pro Ile Gly Gly Ser Leu Gly Arg Gly Ser Ser Leu Asp Ile 
465                 470                 475                 480 


Leu Ser Ser Leu Asn Ser Pro Ala Leu Phe Gly Asp Gln Asp Thr Val 
                485                 490                 495     


Met Lys Ala Ile Gln Glu Ala Arg Lys Met Arg Glu Gln Ile Gln Arg 
            500                 505                 510         


Glu Gln Gln Gln Gln Gln Pro His Gly Val Asp Gly Lys Leu Ser Ser 
        515                 520                 525             


Ile Asn Asn Met Gly Leu Asn Ser Cys Arg Asn Glu Lys Glu Arg Thr 
    530                 535                 540                 


Arg Phe Glu Asn Leu Gly Pro Gln Leu Thr Gly Lys Ser Asn Glu Asp 
545                 550                 555                 560 


Gly Lys Leu Gly Pro Gly Val Ile Asp Leu Thr Arg Pro Glu Asp Ala 
                565                 570                 575     


Glu Gly Gly Ala Thr Val Ala Glu Ala Arg Val Tyr Arg Asp Ala Arg 
            580                 585                 590         


Gly Arg Ala Ser Ser Glu Pro His Ile Lys Arg Pro Met Asn Ala Phe 
        595                 600                 605             


Met Val Trp Ala Lys Asp Glu Arg Arg Lys Ile Leu Gln Ala Phe Pro 
    610                 615                 620                 


Asp Met His Asn Ser Asn Ile Ser Lys Ile Leu Gly Ser Arg Trp Lys 
625                 630                 635                 640 


Ser Met Ser Asn Gln Glu Lys Gln Pro Tyr Tyr Glu Glu Gln Ala Arg 
                645                 650                 655     


Leu Ser Lys Ile His Leu Glu Lys Tyr Pro Asn Tyr Lys Tyr Lys Pro 
            660                 665                 670         


Arg Pro Lys Arg Thr Cys Ile Val Asp Gly Lys Lys Leu Arg Ile Gly 
        675                 680                 685             


Glu Tyr Lys Gln Leu Met Arg Ser Arg Arg Gln Glu Met Arg Gln Phe 
    690                 695                 700                 


Phe Thr Val Gly Gln Gln Pro Gln Ile Pro Ile Thr Thr Gly Thr Gly 
705                 710                 715                 720 


Val Val Tyr Pro Gly Ala Ile Thr Met Ala Thr Thr Thr Pro Ser Pro 
                725                 730                 735     


Gln Met Thr Ser Asp Cys Ser Ser Thr Ser Ala Ser Pro Glu Pro Ser 
            740                 745                 750         


Leu Pro Val Ile Gln Ser Thr Tyr Gly Met Lys Thr Asp Gly Gly Ser 
        755                 760                 765             


Leu Ala Gly Asn Glu Met Ile Asn Gly Glu Asp Glu Met Glu Met Tyr 
    770                 775                 780                 


Asp Asp Tyr Glu Asp Asp Pro Lys Ser Asp Tyr Ser Ser Glu Asn Glu 
785                 790                 795                 800 


Ala Pro Glu Ala Val Ser Ala Asn 
                805             


<210>  3515
<211>  801
<212>  PRT
<213>  homo sapiens

<400>  3515

Met Ser Ser Lys Gln Ala Thr Ser Pro Phe Ala Cys Ala Ala Asp Gly 
1               5                   10                  15      


Glu Asp Ala Met Thr Gln Asp Leu Thr Ser Arg Glu Lys Glu Glu Gly 
            20                  25                  30          


Ser Asp Gln His Val Ala Ser His Leu Pro Leu His Pro Ile Met His 
        35                  40                  45              


Asn Lys Pro His Ser Glu Glu Leu Pro Thr Leu Val Ser Thr Ile Gln 
    50                  55                  60                  


Gln Asp Ala Asp Trp Asp Ser Val Leu Ser Ser Gln Gln Arg Met Glu 
65                  70                  75                  80  


Ser Glu Asn Asn Lys Leu Cys Ser Leu Tyr Ser Phe Arg Asn Thr Ser 
                85                  90                  95      


Thr Ser Pro His Lys Pro Asp Glu Gly Ser Arg Asp Arg Glu Ile Met 
            100                 105                 110         


Thr Ser Val Thr Phe Gly Thr Pro Glu Arg Arg Lys Gly Ser Leu Ala 
        115                 120                 125             


Asp Val Val Asp Thr Leu Lys Gln Lys Lys Leu Glu Glu Met Thr Arg 
    130                 135                 140                 


Thr Glu Gln Glu Asp Ser Ser Cys Met Glu Lys Leu Leu Ser Lys Asp 
145                 150                 155                 160 


Trp Lys Glu Lys Met Glu Arg Leu Asn Thr Ser Glu Leu Leu Gly Glu 
                165                 170                 175     


Ile Lys Gly Thr Pro Glu Ser Leu Ala Glu Lys Glu Arg Gln Leu Ser 
            180                 185                 190         


Thr Met Ile Thr Gln Leu Ile Ser Leu Arg Glu Gln Leu Leu Ala Ala 
        195                 200                 205             


His Asp Glu Gln Lys Lys Leu Ala Ala Ser Gln Ile Glu Lys Gln Arg 
    210                 215                 220                 


Gln Gln Met Asp Leu Ala Arg Gln Gln Gln Glu Gln Ile Ala Arg Gln 
225                 230                 235                 240 


Gln Gln Gln Leu Leu Gln Gln Gln His Lys Ile Asn Leu Leu Gln Gln 
                245                 250                 255     


Gln Ile Gln Val Gln Gly His Met Pro Pro Leu Met Ile Pro Ile Phe 
            260                 265                 270         


Pro His Asp Gln Arg Thr Leu Ala Ala Ala Ala Ala Ala Gln Gln Gly 
        275                 280                 285             


Phe Leu Phe Pro Pro Gly Ile Thr Tyr Lys Pro Gly Asp Asn Tyr Pro 
    290                 295                 300                 


Val Gln Phe Ile Pro Ser Thr Met Ala Ala Ala Ala Ala Ser Gly Leu 
305                 310                 315                 320 


Ser Pro Leu Gln Leu Gln Gln Leu Tyr Ala Ala Gln Leu Ala Ser Met 
                325                 330                 335     


Gln Val Ser Pro Gly Ala Lys Met Pro Ser Thr Pro Gln Pro Pro Asn 
            340                 345                 350         


Thr Ala Gly Thr Val Ser Pro Thr Gly Ile Lys Asn Glu Lys Arg Gly 
        355                 360                 365             


Thr Ser Pro Val Thr Gln Val Lys Asp Glu Ala Ala Ala Gln Pro Leu 
    370                 375                 380                 


Asn Leu Ser Ser Arg Pro Lys Thr Ala Glu Pro Val Lys Ser Pro Thr 
385                 390                 395                 400 


Ser Pro Thr Gln Asn Leu Phe Pro Ala Ser Lys Thr Ser Pro Val Asn 
                405                 410                 415     


Leu Pro Asn Lys Ser Ser Ile Pro Ser Pro Ile Gly Gly Ser Leu Gly 
            420                 425                 430         


Arg Gly Ser Ser Leu Gly Lys Trp Lys Ser Gln His Gln Glu Glu Thr 
        435                 440                 445             


Tyr Glu Leu Asp Ile Leu Ser Ser Leu Asn Ser Pro Ala Leu Phe Gly 
    450                 455                 460                 


Asp Gln Asp Thr Val Met Lys Ala Ile Gln Glu Ala Arg Lys Met Arg 
465                 470                 475                 480 


Glu Gln Ile Gln Arg Glu Gln Gln Gln Gln Gln Pro His Gly Val Asp 
                485                 490                 495     


Gly Lys Leu Ser Ser Ile Asn Asn Met Gly Leu Asn Ser Cys Arg Asn 
            500                 505                 510         


Glu Lys Glu Arg Thr Arg Phe Glu Asn Leu Gly Pro Gln Leu Thr Gly 
        515                 520                 525             


Lys Ser Asn Glu Asp Gly Lys Leu Gly Pro Gly Val Ile Asp Leu Thr 
    530                 535                 540                 


Arg Pro Glu Asp Ala Glu Gly Ser Lys Ala Met Asn Gly Ser Ala Ala 
545                 550                 555                 560 


Lys Leu Gln Gln Tyr Tyr Cys Trp Pro Thr Gly Gly Ala Thr Val Ala 
                565                 570                 575     


Glu Ala Arg Val Tyr Arg Asp Ala Arg Gly Arg Ala Ser Ser Glu Pro 
            580                 585                 590         


His Ile Lys Arg Pro Met Asn Ala Phe Met Val Trp Ala Lys Asp Glu 
        595                 600                 605             


Arg Arg Lys Ile Leu Gln Ala Phe Pro Asp Met His Asn Ser Asn Ile 
    610                 615                 620                 


Ser Lys Ile Leu Gly Ser Arg Trp Lys Ser Met Ser Asn Gln Glu Lys 
625                 630                 635                 640 


Gln Pro Tyr Tyr Glu Glu Gln Ala Arg Leu Ser Lys Ile His Leu Glu 
                645                 650                 655     


Lys Tyr Pro Asn Tyr Lys Tyr Lys Pro Arg Pro Lys Arg Thr Cys Ile 
            660                 665                 670         


Val Asp Gly Lys Lys Leu Arg Ile Gly Glu Tyr Lys Gln Leu Met Arg 
        675                 680                 685             


Ser Arg Arg Gln Glu Met Arg Gln Phe Phe Thr Val Gly Gln Gln Pro 
    690                 695                 700                 


Gln Ile Pro Ile Thr Thr Gly Thr Gly Val Val Tyr Pro Gly Ala Ile 
705                 710                 715                 720 


Thr Met Ala Thr Thr Thr Pro Ser Pro Gln Met Thr Ser Asp Cys Ser 
                725                 730                 735     


Ser Thr Ser Ala Ser Pro Glu Pro Ser Leu Pro Val Ile Gln Ser Thr 
            740                 745                 750         


Tyr Gly Met Lys Thr Asp Gly Gly Ser Leu Ala Gly Asn Glu Met Ile 
        755                 760                 765             


Asn Gly Glu Asp Glu Met Glu Met Tyr Asp Asp Tyr Glu Asp Asp Pro 
    770                 775                 780                 


Lys Ser Asp Tyr Ser Ser Glu Asn Glu Ala Pro Glu Ala Val Ser Ala 
785                 790                 795                 800 


Asn 
    


<210>  3516
<211>  453
<212>  PRT
<213>  homo sapiens

<400>  3516

Met Gly Val Lys Thr Phe Thr His Ser Ser Ser Ser His Ser Gln Glu 
1               5                   10                  15      


Met Leu Gly Lys Leu Asn Met Leu Arg Asn Asp Gly His Phe Cys Asp 
            20                  25                  30          


Ile Thr Ile Arg Val Gln Asp Lys Ile Phe Arg Ala His Lys Val Val 
        35                  40                  45              


Leu Ala Ala Cys Ser Asp Phe Phe Arg Thr Lys Leu Val Gly Gln Ala 
    50                  55                  60                  


Glu Asp Glu Asn Lys Asn Val Leu Asp Leu His His Val Thr Val Thr 
65                  70                  75                  80  


Gly Phe Ile Pro Leu Leu Glu Tyr Ala Tyr Thr Ala Thr Leu Ser Ile 
                85                  90                  95      


Asn Thr Glu Asn Ile Ile Asp Val Leu Ala Ala Ala Ser Tyr Met Gln 
            100                 105                 110         


Met Phe Ser Val Ala Ser Thr Cys Ser Glu Phe Met Lys Ser Ser Ile 
        115                 120                 125             


Leu Trp Asn Thr Pro Asn Ser Gln Pro Glu Lys Gly Leu Asp Ala Gly 
    130                 135                 140                 


Gln Glu Asn Asn Ser Asn Cys Asn Phe Thr Ser Arg Asp Gly Ser Ile 
145                 150                 155                 160 


Ser Pro Val Ser Ser Glu Cys Ser Val Val Glu Arg Thr Ile Pro Val 
                165                 170                 175     


Cys Arg Glu Ser Arg Arg Lys Arg Lys Ser Tyr Ile Val Met Ser Pro 
            180                 185                 190         


Glu Ser Pro Val Lys Cys Gly Thr Gln Thr Ser Ser Pro Gln Val Leu 
        195                 200                 205             


Asn Ser Ser Ala Ser Tyr Ser Glu Asn Arg Asn Gln Pro Val Asp Ser 
    210                 215                 220                 


Ser Leu Ala Phe Pro Trp Thr Phe Pro Phe Gly Ile Asp Arg Arg Ile 
225                 230                 235                 240 


Gln Pro Glu Lys Val Lys Gln Ala Glu Asn Thr Arg Thr Leu Glu Leu 
                245                 250                 255     


Pro Gly Pro Ser Glu Thr Gly Arg Arg Met Ala Asp Tyr Val Thr Cys 
            260                 265                 270         


Glu Ser Thr Lys Thr Thr Leu Pro Leu Gly Thr Glu Glu Asp Val Arg 
        275                 280                 285             


Val Lys Val Glu Arg Leu Ser Asp Glu Glu Val His Glu Glu Val Ser 
    290                 295                 300                 


Gln Pro Val Ser Ala Ser Gln Ser Ser Leu Ser Asp Gln Gln Thr Val 
305                 310                 315                 320 


Pro Gly Ser Glu Gln Val Gln Glu Asp Leu Leu Ile Ser Pro Gln Ser 
                325                 330                 335     


Ser Ser Ile Gly Ser Val Asp Glu Gly Val Ser Glu Gly Leu Pro Thr 
            340                 345                 350         


Leu Gln Ser Thr Ser Ser Thr Asn Ala Pro Pro Asp Asp Asp Asp Arg 
        355                 360                 365             


Leu Glu Asn Val Gln Tyr Pro Tyr Gln Leu Tyr Ile Ala Pro Ser Thr 
    370                 375                 380                 


Ser Ser Thr Glu Arg Pro Ser Pro Asn Gly Pro Asp Arg Pro Phe Gln 
385                 390                 395                 400 


Cys Pro Thr Cys Gly Val Arg Phe Thr Arg Ile Gln Asn Leu Lys Gln 
                405                 410                 415     


His Met Leu Ile His Ser Gly Ile Lys Pro Phe Gln Cys Asp Arg Cys 
            420                 425                 430         


Gly Lys Lys Phe Thr Arg Ala Tyr Ser Leu Lys Met His Arg Leu Lys 
        435                 440                 445             


His Glu Val Ile Ser 
    450             


<210>  3517
<211>  1220
<212>  PRT
<213>  homo sapiens

<400>  3517

Met Gly Lys Lys Gln Lys Asn Lys Ser Glu Asp Ser Thr Lys Asp Asp 
1               5                   10                  15      


Ile Asp Leu Asp Ala Leu Ala Ala Glu Ile Glu Gly Ala Gly Ala Ala 
            20                  25                  30          


Lys Glu Gln Glu Pro Gln Lys Ser Lys Gly Lys Lys Lys Lys Glu Lys 
        35                  40                  45              


Lys Lys Gln Asp Phe Asp Glu Asp Asp Ile Leu Lys Glu Leu Glu Glu 
    50                  55                  60                  


Leu Ser Leu Glu Ala Gln Gly Ile Lys Ala Asp Arg Glu Thr Val Ala 
65                  70                  75                  80  


Val Lys Pro Thr Glu Asn Asn Glu Glu Glu Phe Thr Ser Lys Asp Lys 
                85                  90                  95      


Lys Lys Lys Gly Gln Lys Gly Lys Lys Gln Ser Phe Asp Asp Asn Asp 
            100                 105                 110         


Ser Glu Glu Leu Glu Asp Lys Asp Ser Lys Ser Lys Lys Thr Ala Lys 
        115                 120                 125             


Pro Lys Val Glu Met Tyr Ser Gly Ser Asp Asp Asp Asp Asp Phe Asn 
    130                 135                 140                 


Lys Leu Pro Lys Lys Ala Lys Gly Lys Ala Gln Lys Ser Asn Lys Lys 
145                 150                 155                 160 


Trp Asp Gly Ser Glu Glu Asp Glu Asp Asn Ser Lys Lys Ile Lys Glu 
                165                 170                 175     


Arg Ser Arg Ile Asn Ser Ser Gly Glu Ser Gly Asp Glu Ser Asp Glu 
            180                 185                 190         


Phe Leu Gln Ser Arg Lys Gly Gln Lys Lys Asn Gln Lys Asn Lys Pro 
        195                 200                 205             


Gly Pro Asn Ile Glu Ser Gly Asn Glu Asp Asp Asp Ala Ser Phe Lys 
    210                 215                 220                 


Ile Lys Thr Val Ala Gln Lys Lys Ala Glu Lys Lys Glu Arg Glu Arg 
225                 230                 235                 240 


Lys Lys Arg Asp Glu Glu Lys Ala Lys Leu Arg Lys Leu Lys Glu Lys 
                245                 250                 255     


Glu Glu Leu Glu Thr Gly Lys Lys Asp Gln Ser Lys Gln Lys Glu Ser 
            260                 265                 270         


Gln Arg Lys Phe Glu Glu Glu Thr Val Lys Ser Lys Val Thr Val Asp 
        275                 280                 285             


Thr Gly Val Ile Pro Ala Ser Glu Glu Lys Ala Glu Thr Pro Thr Ala 
    290                 295                 300                 


Ala Glu Asp Asp Asn Glu Gly Asp Lys Lys Lys Lys Asp Lys Lys Lys 
305                 310                 315                 320 


Lys Lys Gly Glu Lys Glu Glu Lys Glu Lys Glu Lys Lys Lys Gly Pro 
                325                 330                 335     


Ser Lys Ala Thr Val Lys Ala Met Gln Glu Ala Leu Ala Lys Leu Lys 
            340                 345                 350         


Glu Glu Glu Glu Arg Gln Lys Arg Glu Glu Glu Glu Arg Ile Lys Arg 
        355                 360                 365             


Leu Glu Glu Leu Glu Ala Lys Arg Lys Glu Glu Glu Arg Leu Glu Gln 
    370                 375                 380                 


Glu Lys Arg Glu Arg Lys Lys Gln Lys Glu Lys Glu Arg Lys Glu Arg 
385                 390                 395                 400 


Leu Lys Lys Glu Gly Lys Leu Leu Thr Lys Ser Gln Arg Glu Ala Arg 
                405                 410                 415     


Ala Arg Ala Glu Ala Thr Leu Lys Leu Leu Gln Ala Gln Gly Val Glu 
            420                 425                 430         


Val Pro Ser Lys Asp Ser Leu Pro Lys Lys Arg Pro Ile Tyr Glu Asp 
        435                 440                 445             


Lys Lys Arg Lys Lys Ile Pro Gln Gln Leu Glu Ser Lys Glu Val Ser 
    450                 455                 460                 


Glu Ser Met Glu Leu Cys Ala Ala Val Glu Val Met Glu Gln Gly Val 
465                 470                 475                 480 


Pro Glu Lys Glu Glu Thr Pro Pro Pro Val Glu Pro Glu Glu Glu Glu 
                485                 490                 495     


Asp Thr Glu Asp Ala Gly Leu Asp Asp Trp Glu Ala Met Ala Ser Asp 
            500                 505                 510         


Glu Glu Thr Glu Lys Val Glu Gly Asn Lys Val His Ile Glu Val Lys 
        515                 520                 525             


Glu Asn Pro Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp 
    530                 535                 540                 


Glu Glu Ser Glu Glu Glu Glu Glu Glu Glu Gly Glu Ser Glu Gly Ser 
545                 550                 555                 560 


Glu Gly Asp Glu Glu Asp Glu Lys Val Ser Asp Glu Lys Asp Ser Gly 
                565                 570                 575     


Lys Thr Leu Asp Lys Lys Pro Ser Lys Glu Met Ser Ser Asp Ser Glu 
            580                 585                 590         


Tyr Asp Ser Asp Asp Asp Arg Thr Lys Glu Glu Arg Ala Tyr Asp Lys 
        595                 600                 605             


Ala Lys Arg Arg Ile Glu Lys Arg Arg Leu Glu His Ser Lys Asn Val 
    610                 615                 620                 


Asn Thr Glu Lys Leu Arg Ala Pro Ile Ile Cys Val Leu Gly His Val 
625                 630                 635                 640 


Asp Thr Gly Lys Thr Lys Ile Leu Asp Lys Leu Arg His Thr His Val 
                645                 650                 655     


Gln Asp Gly Glu Ala Gly Gly Ile Thr Gln Gln Ile Gly Ala Thr Asn 
            660                 665                 670         


Val Pro Leu Glu Ala Ile Asn Glu Gln Thr Lys Met Ile Lys Asn Phe 
        675                 680                 685             


Asp Arg Glu Asn Val Arg Ile Pro Gly Met Leu Ile Ile Asp Thr Pro 
    690                 695                 700                 


Gly His Glu Ser Phe Ser Asn Leu Arg Asn Arg Gly Ser Ser Leu Cys 
705                 710                 715                 720 


Asp Ile Ala Ile Leu Val Val Asp Ile Met His Gly Leu Glu Pro Gln 
                725                 730                 735     


Thr Ile Glu Ser Ile Asn Leu Leu Lys Ser Lys Lys Cys Pro Phe Ile 
            740                 745                 750         


Val Ala Leu Asn Lys Ile Asp Arg Leu Tyr Asp Trp Lys Lys Ser Pro 
        755                 760                 765             


Asp Ser Asp Val Ala Ala Thr Leu Lys Lys Gln Lys Lys Asn Thr Lys 
    770                 775                 780                 


Asp Glu Phe Glu Glu Arg Ala Lys Ala Ile Ile Val Glu Phe Ala Gln 
785                 790                 795                 800 


Gln Gly Leu Asn Ala Ala Leu Phe Tyr Glu Asn Lys Asp Pro Arg Thr 
                805                 810                 815     


Phe Val Ser Leu Val Pro Thr Ser Ala His Thr Gly Asp Gly Met Gly 
            820                 825                 830         


Ser Leu Ile Tyr Leu Leu Val Glu Leu Thr Gln Thr Met Leu Ser Lys 
        835                 840                 845             


Arg Leu Ala His Cys Glu Glu Leu Arg Ala Gln Val Met Glu Val Lys 
    850                 855                 860                 


Ala Leu Pro Gly Met Gly Thr Thr Ile Asp Val Ile Leu Ile Asn Gly 
865                 870                 875                 880 


Arg Leu Lys Glu Gly Asp Thr Ile Ile Val Pro Gly Val Glu Gly Pro 
                885                 890                 895     


Ile Val Thr Gln Ile Arg Gly Leu Leu Leu Pro Pro Pro Met Lys Glu 
            900                 905                 910         


Leu Arg Val Lys Asn Gln Tyr Glu Lys His Lys Glu Val Glu Ala Ala 
        915                 920                 925             


Gln Gly Val Lys Ile Leu Gly Lys Asp Leu Glu Lys Thr Leu Ala Gly 
    930                 935                 940                 


Leu Pro Leu Leu Val Ala Tyr Lys Glu Asp Glu Ile Pro Val Leu Lys 
945                 950                 955                 960 


Asp Glu Leu Ile His Glu Leu Lys Gln Thr Leu Asn Ala Ile Lys Leu 
                965                 970                 975     


Glu Glu Lys Gly Val Tyr Val Gln Ala Ser Thr Leu Gly Ser Leu Glu 
            980                 985                 990         


Ala Leu Leu Glu Phe Leu Lys Thr  Ser Glu Val Pro Tyr  Ala Gly Ile 
        995                 1000                 1005             


Asn Ile  Gly Pro Val His Lys  Lys Asp Val Met Lys  Ala Ser Val 
    1010                 1015                 1020             


Met Leu  Glu His Asp Pro Gln  Tyr Ala Val Ile Leu  Ala Phe Asp 
    1025                 1030                 1035             


Val Arg  Ile Glu Arg Asp Ala  Gln Glu Met Ala Asp  Ser Leu Gly 
    1040                 1045                 1050             


Val Arg  Ile Phe Ser Ala Glu  Ile Ile Tyr His Leu  Phe Asp Ala 
    1055                 1060                 1065             


Phe Thr  Lys Tyr Arg Gln Asp  Tyr Lys Lys Gln Lys  Gln Glu Glu 
    1070                 1075                 1080             


Phe Lys  His Ile Ala Val Phe  Pro Cys Lys Ile Lys  Ile Leu Pro 
    1085                 1090                 1095             


Gln Tyr  Ile Phe Asn Ser Arg  Asp Pro Ile Val Met  Gly Val Thr 
    1100                 1105                 1110             


Val Glu  Ala Gly Gln Val Lys  Gln Gly Thr Pro Met  Cys Val Pro 
    1115                 1120                 1125             


Ser Lys  Asn Phe Val Asp Ile  Gly Ile Val Thr Ser  Ile Glu Ile 
    1130                 1135                 1140             


Asn His  Lys Gln Val Asp Val  Ala Lys Lys Gly Gln  Glu Val Cys 
    1145                 1150                 1155             


Val Lys  Ile Glu Pro Ile Pro  Gly Glu Ser Pro Lys  Met Phe Gly 
    1160                 1165                 1170             


Arg His  Phe Glu Ala Thr Asp  Ile Leu Val Ser Lys  Ile Ser Arg 
    1175                 1180                 1185             


Gln Ser  Ile Asp Ala Leu Lys  Asp Trp Phe Arg Asp  Glu Met Gln 
    1190                 1195                 1200             


Lys Ser  Asp Trp Gln Leu Ile  Val Glu Leu Lys Lys  Val Phe Glu 
    1205                 1210                 1215             


Ile Ile  
    1220 


<210>  3518
<211>  846
<212>  PRT
<213>  homo sapiens

<400>  3518

Met Lys Met Ala Asp Arg Ser Gly Lys Ile Ile Pro Gly Gln Val Tyr 
1               5                   10                  15      


Ile Glu Val Glu Tyr Asp Tyr Glu Tyr Glu Ala Lys Asp Arg Lys Ile 
            20                  25                  30          


Val Ile Lys Gln Gly Glu Arg Tyr Ile Leu Val Lys Lys Thr Asn Asp 
        35                  40                  45              


Asp Trp Trp Gln Val Lys Pro Asp Glu Asn Ser Lys Ala Phe Tyr Val 
    50                  55                  60                  


Pro Ala Gln Tyr Val Lys Glu Val Thr Arg Lys Ala Leu Met Pro Pro 
65                  70                  75                  80  


Val Lys Gln Val Ala Gly Leu Pro Asn Asn Ser Thr Lys Ile Met Gln 
                85                  90                  95      


Ser Leu His Leu Gln Arg Ser Thr Glu Asn Val Asn Lys Leu Pro Glu 
            100                 105                 110         


Leu Ser Ser Phe Gly Lys Pro Ser Ser Ser Val Gln Gly Thr Gly Leu 
        115                 120                 125             


Ile Arg Asp Ala Asn Gln Asn Phe Gly Pro Ser Tyr Asn Gln Gly Gln 
    130                 135                 140                 


Thr Val Asn Leu Ser Leu Asp Leu Thr His Asn Asn Gly Lys Phe Asn 
145                 150                 155                 160 


Asn Asp Ser His Ser Pro Lys Val Ser Ser Gln Asn Arg Thr Arg Ser 
                165                 170                 175     


Phe Gly His Phe Pro Gly Pro Glu Phe Leu Asp Val Glu Lys Thr Ser 
            180                 185                 190         


Phe Ser Gln Glu Gln Ser Cys Asp Ser Ala Gly Glu Gly Ser Glu Arg 
        195                 200                 205             


Ile His Gln Asp Ser Glu Ser Gly Asp Glu Leu Ser Ser Ser Ser Thr 
    210                 215                 220                 


Glu Gln Ile Arg Ala Thr Thr Pro Pro Asn Gln Gly Arg Pro Asp Ser 
225                 230                 235                 240 


Pro Val Tyr Ala Asn Leu Gln Glu Leu Lys Ile Ser Gln Ser Ala Leu 
                245                 250                 255     


Pro Pro Leu Pro Gly Ser Pro Ala Ile Gln Ile Asn Gly Glu Trp Glu 
            260                 265                 270         


Thr His Lys Asp Ser Ser Gly Arg Cys Tyr Tyr Tyr Asn Arg Gly Thr 
        275                 280                 285             


Gln Glu Arg Thr Trp Lys Pro Pro Arg Trp Thr Arg Asp Ala Ser Ile 
    290                 295                 300                 


Ser Lys Gly Asp Phe Gln Asn Pro Gly Asp Gln Glu Leu Leu Ser Ser 
305                 310                 315                 320 


Glu Glu Asn Tyr Tyr Ser Thr Ser Tyr Ser Gln Ser Asp Ser Gln Cys 
                325                 330                 335     


Gly Ser Pro Pro Arg Gly Trp Ser Glu Glu Leu Asp Glu Arg Gly His 
            340                 345                 350         


Thr Leu Tyr Thr Ser Asp Tyr Thr Asn Glu Lys Trp Leu Lys His Val 
        355                 360                 365             


Asp Asp Gln Gly Arg Gln Tyr Tyr Tyr Ser Ala Asp Gly Ser Arg Ser 
    370                 375                 380                 


Glu Trp Glu Leu Pro Lys Tyr Asn Ala Ser Ser Gln Gln Gln Arg Glu 
385                 390                 395                 400 


Ile Ile Lys Ser Arg Ser Leu Asp Arg Arg Leu Gln Glu Pro Ile Val 
                405                 410                 415     


Leu Thr Lys Trp Arg His Ser Thr Ile Val Leu Asp Thr Asn Asp Lys 
            420                 425                 430         


Glu Ser Pro Thr Ala Ser Lys Pro Cys Phe Pro Glu Asn Glu Ser Ser 
        435                 440                 445             


Pro Ser Ser Pro Lys His Gln Asp Thr Ala Ser Ser Pro Lys Asp Gln 
    450                 455                 460                 


Glu Lys Tyr Gly Leu Leu Asn Val Thr Lys Ile Ala Glu Asn Gly Lys 
465                 470                 475                 480 


Lys Val Arg Lys Asn Trp Leu Ser Ser Trp Ala Val Leu Gln Gly Ser 
                485                 490                 495     


Ser Leu Leu Phe Thr Lys Thr Gln Gly Ser Ser Thr Ser Trp Phe Gly 
            500                 505                 510         


Ser Asn Gln Ser Lys Pro Glu Phe Thr Val Asp Leu Lys Gly Ala Thr 
        515                 520                 525             


Ile Glu Met Ala Ser Lys Asp Lys Ser Ser Lys Lys Asn Val Phe Glu 
    530                 535                 540                 


Leu Lys Thr Arg Gln Gly Thr Glu Leu Leu Ile Gln Ser Asp Asn Asp 
545                 550                 555                 560 


Thr Val Ile Asn Asp Trp Phe Lys Val Leu Ser Ser Thr Ile Asn Asn 
                565                 570                 575     


Gln Ala Val Glu Thr Asp Glu Gly Ile Glu Glu Glu Ile Pro Asp Ser 
            580                 585                 590         


Pro Gly Ile Glu Lys His Asp Lys Glu Lys Glu Gln Lys Asp Pro Lys 
        595                 600                 605             


Lys Leu Arg Ser Phe Lys Val Ser Ser Ile Asp Ser Ser Glu Gln Lys 
    610                 615                 620                 


Lys Thr Lys Lys Asn Leu Lys Lys Phe Leu Thr Arg Arg Pro Thr Leu 
625                 630                 635                 640 


Gln Ala Val Arg Glu Lys Gly Tyr Ile Lys Asp Gln Val Phe Gly Ser 
                645                 650                 655     


Asn Leu Ala Asn Leu Cys Gln Arg Glu Asn Gly Thr Val Pro Lys Phe 
            660                 665                 670         


Val Lys Leu Cys Ile Glu His Val Glu Glu His Gly Leu Asp Ile Asp 
        675                 680                 685             


Gly Ile Tyr Arg Val Ser Gly Asn Leu Ala Val Ile Gln Lys Leu Arg 
    690                 695                 700                 


Phe Ala Val Asn His Asp Glu Lys Leu Asp Leu Asn Asp Ser Lys Trp 
705                 710                 715                 720 


Glu Asp Ile His Val Ile Thr Gly Ala Leu Lys Met Phe Phe Arg Glu 
                725                 730                 735     


Leu Pro Glu Pro Leu Phe Thr Phe Asn His Phe Asn Asp Phe Val Asn 
            740                 745                 750         


Ala Ile Lys Gln Glu Pro Arg Gln Arg Val Ala Ala Val Lys Asp Leu 
        755                 760                 765             


Ile Arg Gln Leu Pro Lys Pro Asn Gln Asp Thr Met Gln Ile Leu Phe 
    770                 775                 780                 


Arg His Leu Arg Arg Val Ile Glu Asn Gly Glu Lys Asn Arg Met Thr 
785                 790                 795                 800 


Tyr Gln Ser Ile Ala Ile Val Phe Gly Pro Thr Leu Leu Lys Pro Glu 
                805                 810                 815     


Lys Glu Thr Gly Asn Ile Ala Val His Thr Val Tyr Gln Asn Gln Ile 
            820                 825                 830         


Val Glu Leu Ile Leu Leu Glu Leu Ser Ser Ile Phe Gly Arg 
        835                 840                 845     


<210>  3519
<211>  403
<212>  PRT
<213>  homo sapiens

<400>  3519

Met Phe Val Ala Ser Glu Arg Lys Met Arg Ala His Gln Val Leu Thr 
1               5                   10                  15      


Phe Leu Leu Leu Phe Val Ile Thr Ser Val Ala Ser Glu Asn Ala Ser 
            20                  25                  30          


Thr Ser Arg Gly Cys Gly Leu Asp Leu Leu Pro Gln Tyr Val Ser Leu 
        35                  40                  45              


Cys Asp Leu Asp Ala Ile Trp Gly Ile Val Val Glu Ala Val Ala Gly 
    50                  55                  60                  


Ala Gly Ala Leu Ile Thr Leu Leu Leu Met Leu Ile Leu Leu Val Arg 
65                  70                  75                  80  


Leu Pro Phe Ile Lys Glu Lys Glu Lys Lys Ser Pro Val Gly Leu His 
                85                  90                  95      


Phe Leu Phe Leu Leu Gly Thr Leu Gly Leu Phe Gly Leu Thr Phe Ala 
            100                 105                 110         


Phe Ile Ile Gln Glu Asp Glu Thr Ile Cys Ser Val Arg Arg Phe Leu 
        115                 120                 125             


Trp Gly Val Leu Phe Ala Leu Cys Phe Ser Cys Leu Leu Ser Gln Ala 
    130                 135                 140                 


Trp Arg Val Arg Arg Leu Val Arg His Gly Thr Gly Pro Ala Gly Trp 
145                 150                 155                 160 


Gln Leu Val Gly Leu Ala Leu Cys Leu Met Leu Val Gln Val Ile Ile 
                165                 170                 175     


Ala Val Glu Trp Leu Val Leu Thr Val Leu Arg Asp Thr Arg Pro Ala 
            180                 185                 190         


Cys Ala Tyr Glu Pro Met Asp Phe Val Met Ala Leu Ile Tyr Asp Met 
        195                 200                 205             


Val Leu Leu Val Val Thr Leu Gly Leu Ala Leu Phe Thr Leu Cys Gly 
    210                 215                 220                 


Lys Phe Lys Arg Trp Lys Leu Asn Gly Ala Phe Leu Leu Ile Thr Ala 
225                 230                 235                 240 


Phe Leu Ser Val Leu Ile Trp Val Ala Trp Met Thr Met Tyr Leu Phe 
                245                 250                 255     


Gly Asn Val Lys Leu Gln Gln Gly Asp Ala Trp Asn Asp Pro Thr Leu 
            260                 265                 270         


Ala Ile Thr Leu Ala Ala Ser Gly Trp Val Phe Val Ile Phe His Ala 
        275                 280                 285             


Ile Pro Glu Ile His Cys Thr Leu Leu Pro Ala Leu Gln Glu Asn Thr 
    290                 295                 300                 


Pro Asn Tyr Phe Asp Thr Ser Gln Pro Arg Met Arg Glu Thr Ala Phe 
305                 310                 315                 320 


Glu Glu Asp Val Gln Leu Pro Arg Ala Tyr Met Glu Asn Lys Ala Phe 
                325                 330                 335     


Ser Met Asp Glu His Asn Ala Ala Leu Arg Thr Ala Gly Phe Pro Asn 
            340                 345                 350         


Gly Ser Leu Gly Lys Arg Pro Ser Gly Ser Leu Gly Lys Arg Pro Ser 
        355                 360                 365             


Ala Pro Phe Arg Ser Asn Val Tyr Gln Pro Thr Glu Met Ala Val Val 
    370                 375                 380                 


Leu Asn Gly Gly Thr Ile Pro Thr Ala Pro Pro Ser His Thr Gly Arg 
385                 390                 395                 400 


His Leu Trp 
            


<210>  3520
<211>  523
<212>  PRT
<213>  homo sapiens

<400>  3520

Met Gln Arg Ala Ala Ala Leu Val Arg Arg Gly Cys Gly Pro Arg Thr 
1               5                   10                  15      


Pro Ser Ser Trp Gly Arg Ser Gln Ser Ser Ala Ala Ala Glu Ala Ser 
            20                  25                  30          


Ala Val Leu Lys Val Arg Pro Glu Arg Ser Arg Arg Glu Arg Ile Leu 
        35                  40                  45              


Thr Leu Glu Ser Met Asn Pro Gln Val Lys Ala Val Glu Tyr Ala Val 
    50                  55                  60                  


Arg Gly Pro Ile Val Leu Lys Ala Gly Glu Ile Glu Leu Glu Leu Gln 
65                  70                  75                  80  


Arg Gly Ile Lys Lys Pro Phe Thr Glu Val Ile Arg Ala Asn Ile Gly 
                85                  90                  95      


Asp Ala Gln Ala Met Gly Gln Gln Pro Ile Thr Phe Leu Arg Gln Val 
            100                 105                 110         


Met Ala Leu Cys Thr Tyr Pro Asn Leu Leu Asp Ser Pro Ser Phe Pro 
        115                 120                 125             


Glu Asp Ala Lys Lys Arg Ala Arg Arg Ile Leu Gln Ala Cys Gly Gly 
    130                 135                 140                 


Asn Ser Leu Gly Ser Tyr Ser Ala Ser Gln Gly Val Asn Cys Ile Arg 
145                 150                 155                 160 


Glu Asp Val Ala Ala Tyr Ile Thr Arg Arg Asp Gly Gly Val Pro Ala 
                165                 170                 175     


Asp Pro Asp Asn Ile Tyr Leu Thr Thr Gly Ala Ser Asp Gly Ile Ser 
            180                 185                 190         


Thr Ile Leu Lys Ile Leu Val Ser Gly Gly Gly Lys Ser Arg Thr Gly 
        195                 200                 205             


Val Met Ile Pro Ile Pro Gln Tyr Pro Leu Tyr Ser Ala Val Ile Ser 
    210                 215                 220                 


Glu Leu Asp Ala Ile Gln Val Asn Tyr Tyr Leu Asp Glu Glu Asn Cys 
225                 230                 235                 240 


Trp Ala Leu Asn Val Asn Glu Leu Arg Arg Ala Val Gln Glu Ala Lys 
                245                 250                 255     


Asp His Cys Asp Pro Lys Val Leu Cys Ile Ile Asn Pro Gly Asn Pro 
            260                 265                 270         


Thr Gly Gln Val Gln Ser Arg Lys Cys Ile Glu Asp Val Ile His Phe 
        275                 280                 285             


Ala Trp Glu Glu Lys Leu Phe Leu Leu Ala Asp Glu Val Tyr Gln Asp 
    290                 295                 300                 


Asn Val Tyr Ser Pro Asp Cys Arg Phe His Ser Phe Lys Lys Val Leu 
305                 310                 315                 320 


Tyr Glu Met Gly Pro Glu Tyr Ser Ser Asn Val Glu Leu Ala Ser Phe 
                325                 330                 335     


His Ser Thr Ser Lys Gly Tyr Met Gly Glu Cys Gly Tyr Arg Gly Gly 
            340                 345                 350         


Tyr Met Glu Val Ile Asn Leu His Pro Glu Ile Lys Gly Gln Leu Val 
        355                 360                 365             


Lys Leu Leu Ser Val Arg Leu Cys Pro Pro Val Ser Gly Gln Ala Ala 
    370                 375                 380                 


Met Asp Ile Val Val Asn Pro Pro Val Ala Gly Glu Glu Ser Phe Glu 
385                 390                 395                 400 


Gln Phe Ser Arg Glu Lys Glu Ser Val Leu Gly Asn Leu Ala Lys Lys 
                405                 410                 415     


Ala Lys Leu Thr Glu Asp Leu Phe Asn Gln Val Pro Gly Ile His Cys 
            420                 425                 430         


Asn Pro Leu Gln Gly Ala Met Tyr Ala Phe Pro Arg Ile Phe Ile Pro 
        435                 440                 445             


Ala Lys Ala Val Glu Ala Ala Gln Ala His Gln Met Ala Pro Asp Met 
    450                 455                 460                 


Phe Tyr Cys Met Lys Leu Leu Glu Glu Thr Gly Ile Cys Val Val Pro 
465                 470                 475                 480 


Gly Ser Gly Phe Gly Gln Arg Glu Gly Thr Tyr His Phe Arg Met Thr 
                485                 490                 495     


Ile Leu Pro Pro Val Glu Lys Leu Lys Thr Val Leu Gln Lys Val Lys 
            500                 505                 510         


Asp Phe His Ile Asn Phe Leu Glu Lys Tyr Ala 
        515                 520             


<210>  3521
<211>  423
<212>  PRT
<213>  homo sapiens

<400>  3521

Met Gly Gln Gln Pro Ile Thr Phe Leu Arg Gln Val Met Ala Leu Cys 
1               5                   10                  15      


Thr Tyr Pro Asn Leu Leu Asp Ser Pro Ser Phe Pro Glu Asp Ala Lys 
            20                  25                  30          


Lys Arg Ala Arg Arg Ile Leu Gln Ala Cys Gly Gly Asn Ser Leu Gly 
        35                  40                  45              


Ser Tyr Ser Ala Ser Gln Gly Val Asn Cys Ile Arg Glu Asp Val Ala 
    50                  55                  60                  


Ala Tyr Ile Thr Arg Arg Asp Gly Gly Val Pro Ala Asp Pro Asp Asn 
65                  70                  75                  80  


Ile Tyr Leu Thr Thr Gly Ala Ser Asp Gly Ile Ser Thr Ile Leu Lys 
                85                  90                  95      


Ile Leu Val Ser Gly Gly Gly Lys Ser Arg Thr Gly Val Met Ile Pro 
            100                 105                 110         


Ile Pro Gln Tyr Pro Leu Tyr Ser Ala Val Ile Ser Glu Leu Asp Ala 
        115                 120                 125             


Ile Gln Val Asn Tyr Tyr Leu Asp Glu Glu Asn Cys Trp Ala Leu Asn 
    130                 135                 140                 


Val Asn Glu Leu Arg Arg Ala Val Gln Glu Ala Lys Asp His Cys Asp 
145                 150                 155                 160 


Pro Lys Val Leu Cys Ile Ile Asn Pro Gly Asn Pro Thr Gly Gln Val 
                165                 170                 175     


Gln Ser Arg Lys Cys Ile Glu Asp Val Ile His Phe Ala Trp Glu Glu 
            180                 185                 190         


Lys Leu Phe Leu Leu Ala Asp Glu Val Tyr Gln Asp Asn Val Tyr Ser 
        195                 200                 205             


Pro Asp Cys Arg Phe His Ser Phe Lys Lys Val Leu Tyr Glu Met Gly 
    210                 215                 220                 


Pro Glu Tyr Ser Ser Asn Val Glu Leu Ala Ser Phe His Ser Thr Ser 
225                 230                 235                 240 


Lys Gly Tyr Met Gly Glu Cys Gly Tyr Arg Gly Gly Tyr Met Glu Val 
                245                 250                 255     


Ile Asn Leu His Pro Glu Ile Lys Gly Gln Leu Val Lys Leu Leu Ser 
            260                 265                 270         


Val Arg Leu Cys Pro Pro Val Ser Gly Gln Ala Ala Met Asp Ile Val 
        275                 280                 285             


Val Asn Pro Pro Val Ala Gly Glu Glu Ser Phe Glu Gln Phe Ser Arg 
    290                 295                 300                 


Glu Lys Glu Ser Val Leu Gly Asn Leu Ala Lys Lys Ala Lys Leu Thr 
305                 310                 315                 320 


Glu Asp Leu Phe Asn Gln Val Pro Gly Ile His Cys Asn Pro Leu Gln 
                325                 330                 335     


Gly Ala Met Tyr Ala Phe Pro Arg Ile Phe Ile Pro Ala Lys Ala Val 
            340                 345                 350         


Glu Ala Ala Gln Ala His Gln Met Ala Pro Asp Met Phe Tyr Cys Met 
        355                 360                 365             


Lys Leu Leu Glu Glu Thr Gly Ile Cys Val Val Pro Gly Ser Gly Phe 
    370                 375                 380                 


Gly Gln Arg Glu Gly Thr Tyr His Phe Arg Met Thr Ile Leu Pro Pro 
385                 390                 395                 400 


Val Glu Lys Leu Lys Thr Val Leu Gln Lys Val Lys Asp Phe His Ile 
                405                 410                 415     


Asn Phe Leu Glu Lys Tyr Ala 
            420             


<210>  3522
<211>  209
<212>  PRT
<213>  homo sapiens

<400>  3522

Met Glu Pro Leu Ala Ala Tyr Pro Leu Lys Cys Ser Gly Pro Arg Ala 
1               5                   10                  15      


Lys Val Phe Ala Val Leu Leu Ser Ile Val Leu Cys Thr Val Thr Leu 
            20                  25                  30          


Phe Leu Leu Gln Leu Lys Phe Leu Lys Pro Lys Ile Asn Ser Phe Tyr 
        35                  40                  45              


Ala Phe Glu Val Lys Asp Ala Lys Gly Arg Thr Val Ser Leu Glu Lys 
    50                  55                  60                  


Tyr Lys Gly Lys Val Ser Leu Val Val Asn Val Ala Ser Asp Cys Gln 
65                  70                  75                  80  


Leu Thr Asp Arg Asn Tyr Leu Gly Leu Lys Glu Leu His Lys Glu Phe 
                85                  90                  95      


Gly Pro Ser His Phe Ser Val Leu Ala Phe Pro Cys Asn Gln Phe Gly 
            100                 105                 110         


Glu Ser Glu Pro Arg Pro Ser Lys Glu Val Glu Ser Phe Ala Arg Lys 
        115                 120                 125             


Asn Tyr Gly Val Thr Phe Pro Ile Phe His Lys Ile Lys Ile Leu Gly 
    130                 135                 140                 


Ser Glu Gly Glu Pro Ala Phe Arg Phe Leu Val Asp Ser Ser Lys Lys 
145                 150                 155                 160 


Glu Pro Arg Trp Asn Phe Trp Lys Tyr Leu Val Asn Pro Glu Gly Gln 
                165                 170                 175     


Val Val Lys Phe Trp Lys Pro Glu Glu Pro Ile Glu Val Ile Arg Pro 
            180                 185                 190         


Asp Ile Ala Ala Leu Val Arg Gln Val Ile Ile Lys Lys Lys Glu Asp 
        195                 200                 205             


Leu 
    


<210>  3523
<211>  184
<212>  PRT
<213>  homo sapiens

<400>  3523

Met Ser Arg Thr Ala Tyr Thr Val Gly Ala Leu Leu Leu Leu Leu Gly 
1               5                   10                  15      


Thr Leu Leu Pro Ala Ala Glu Gly Lys Lys Lys Gly Ser Gln Gly Ala 
            20                  25                  30          


Ile Pro Pro Pro Asp Lys Ala Gln His Asn Asp Ser Glu Gln Thr Gln 
        35                  40                  45              


Ser Pro Gln Gln Pro Gly Ser Arg Asn Arg Gly Arg Gly Gln Gly Arg 
    50                  55                  60                  


Gly Thr Ala Met Pro Gly Glu Glu Val Leu Glu Ser Ser Gln Glu Ala 
65                  70                  75                  80  


Leu His Val Thr Glu Arg Lys Tyr Leu Lys Arg Asp Trp Cys Lys Thr 
                85                  90                  95      


Gln Pro Leu Lys Gln Thr Ile His Glu Glu Gly Cys Asn Ser Arg Thr 
            100                 105                 110         


Ile Ile Asn Arg Phe Cys Tyr Gly Gln Cys Asn Ser Phe Tyr Ile Pro 
        115                 120                 125             


Arg His Ile Arg Lys Glu Glu Gly Ser Phe Gln Ser Cys Ser Phe Cys 
    130                 135                 140                 


Lys Pro Lys Lys Phe Thr Thr Met Met Val Thr Leu Asn Cys Pro Glu 
145                 150                 155                 160 


Leu Gln Pro Pro Thr Lys Lys Lys Arg Val Thr Arg Val Lys Gln Cys 
                165                 170                 175     


Arg Cys Ile Ser Ile Asp Leu Asp 
            180                 


<210>  3524
<211>  767
<212>  PRT
<213>  homo sapiens

<400>  3524

Met Asn Thr Gly Leu Thr Arg Leu Leu Trp Pro Ser Trp Leu Pro Asp 
1               5                   10                  15      


Gly Asp Met Ser His Pro Gln Pro Glu Leu Phe Leu Phe Pro Lys Ala 
            20                  25                  30          


Gln Pro Asn Ser Met Val Val Glu His Pro Glu Phe Leu Lys Ala Gly 
        35                  40                  45              


Lys Glu Pro Gly Leu Gln Ile Trp Arg Val Glu Lys Phe Asp Leu Val 
    50                  55                  60                  


Pro Val Pro Thr Asn Leu Tyr Gly Asp Phe Phe Thr Gly Asp Ala Tyr 
65                  70                  75                  80  


Val Ile Leu Lys Thr Val Gln Leu Arg Asn Gly Asn Leu Gln Tyr Asp 
                85                  90                  95      


Leu His Tyr Trp Leu Gly Asn Glu Cys Ser Gln Asp Glu Ser Gly Ala 
            100                 105                 110         


Ala Ala Ile Phe Thr Val Gln Leu Asp Asp Tyr Leu Asn Gly Arg Ala 
        115                 120                 125             


Val Gln His Arg Glu Val Gln Gly Phe Glu Ser Ala Thr Phe Leu Gly 
    130                 135                 140                 


Tyr Phe Lys Ser Gly Leu Lys Tyr Lys Lys Gly Gly Val Ala Ser Gly 
145                 150                 155                 160 


Phe Lys His Val Val Pro Asn Glu Val Val Val Gln Arg Leu Phe Gln 
                165                 170                 175     


Val Lys Gly Arg Arg Val Val Arg Ala Thr Glu Val Pro Val Ser Trp 
            180                 185                 190         


Glu Ser Phe Asn Asn Gly Asp Cys Phe Ile Leu Asp Leu Gly Asn Asn 
        195                 200                 205             


Ile His Gln Trp Cys Gly Ser Asn Ser Asn Arg Tyr Glu Arg Leu Lys 
    210                 215                 220                 


Ala Thr Gln Val Ser Lys Gly Ile Arg Asp Asn Glu Arg Ser Gly Arg 
225                 230                 235                 240 


Ala Arg Val His Val Ser Glu Glu Gly Thr Glu Pro Glu Ala Met Leu 
                245                 250                 255     


Gln Val Leu Gly Pro Lys Pro Ala Leu Pro Ala Gly Thr Glu Asp Thr 
            260                 265                 270         


Ala Lys Glu Asp Ala Ala Asn Arg Lys Leu Ala Lys Leu Tyr Lys Val 
        275                 280                 285             


Ser Asn Gly Ala Gly Thr Met Ser Val Ser Leu Val Ala Asp Glu Asn 
    290                 295                 300                 


Pro Phe Ala Gln Gly Ala Leu Lys Ser Glu Asp Cys Phe Ile Leu Asp 
305                 310                 315                 320 


His Gly Lys Asp Gly Lys Ile Phe Val Trp Lys Gly Lys Gln Ala Asn 
                325                 330                 335     


Thr Glu Glu Arg Lys Ala Ala Leu Lys Thr Ala Ser Asp Phe Ile Thr 
            340                 345                 350         


Lys Met Asp Tyr Pro Lys Gln Thr Gln Val Ser Val Leu Pro Glu Gly 
        355                 360                 365             


Gly Glu Thr Pro Leu Phe Lys Gln Phe Phe Lys Asn Trp Arg Asp Pro 
    370                 375                 380                 


Asp Gln Thr Asp Gly Leu Gly Leu Ser Tyr Leu Ser Ser His Ile Ala 
385                 390                 395                 400 


Asn Val Glu Arg Val Pro Phe Asp Ala Ala Thr Leu His Thr Ser Thr 
                405                 410                 415     


Ala Met Ala Ala Gln His Gly Met Asp Asp Asp Gly Thr Gly Gln Lys 
            420                 425                 430         


Gln Ile Trp Arg Ile Glu Gly Ser Asn Lys Val Pro Val Asp Pro Ala 
        435                 440                 445             


Thr Tyr Gly Gln Phe Tyr Gly Gly Asp Ser Tyr Ile Ile Leu Tyr Asn 
    450                 455                 460                 


Tyr Arg His Gly Gly Arg Gln Gly Gln Ile Ile Tyr Asn Trp Gln Gly 
465                 470                 475                 480 


Ala Gln Ser Thr Gln Asp Glu Val Ala Ala Ser Ala Ile Leu Thr Ala 
                485                 490                 495     


Gln Leu Asp Glu Glu Leu Gly Gly Thr Pro Val Gln Ser Arg Val Val 
            500                 505                 510         


Gln Gly Lys Glu Pro Ala His Leu Met Ser Leu Phe Gly Gly Lys Pro 
        515                 520                 525             


Met Ile Ile Tyr Lys Gly Gly Thr Ser Arg Glu Gly Gly Gln Thr Ala 
    530                 535                 540                 


Pro Ala Ser Thr Arg Leu Phe Gln Val Arg Ala Asn Ser Ala Gly Ala 
545                 550                 555                 560 


Thr Arg Ala Val Glu Val Leu Pro Lys Ala Gly Ala Leu Asn Ser Asn 
                565                 570                 575     


Asp Ala Phe Val Leu Lys Thr Pro Ser Ala Ala Tyr Leu Trp Val Gly 
            580                 585                 590         


Thr Gly Ala Ser Glu Ala Glu Lys Thr Gly Ala Gln Glu Leu Leu Arg 
        595                 600                 605             


Val Leu Arg Ala Gln Pro Val Gln Val Ala Glu Gly Ser Glu Pro Asp 
    610                 615                 620                 


Gly Phe Trp Glu Ala Leu Gly Gly Lys Ala Ala Tyr Arg Thr Ser Pro 
625                 630                 635                 640 


Arg Leu Lys Asp Lys Lys Met Asp Ala His Pro Pro Arg Leu Phe Ala 
                645                 650                 655     


Cys Ser Asn Lys Ile Gly Arg Phe Val Ile Glu Glu Val Pro Gly Glu 
            660                 665                 670         


Leu Met Gln Glu Asp Leu Ala Thr Asp Asp Val Met Leu Leu Asp Thr 
        675                 680                 685             


Trp Asp Gln Val Phe Val Trp Val Gly Lys Asp Ser Gln Glu Glu Glu 
    690                 695                 700                 


Lys Thr Glu Ala Leu Thr Ser Ala Lys Arg Tyr Ile Glu Thr Asp Pro 
705                 710                 715                 720 


Ala Asn Arg Asp Arg Arg Thr Pro Ile Thr Val Val Lys Gln Gly Phe 
                725                 730                 735     


Glu Pro Pro Ser Phe Val Gly Trp Phe Leu Gly Trp Asp Asp Asp Tyr 
            740                 745                 750         


Trp Ser Val Asp Pro Leu Asp Arg Ala Met Ala Glu Leu Ala Ala 
        755                 760                 765         


<210>  3525
<211>  225
<212>  PRT
<213>  homo sapiens

<400>  3525

Met Ser Cys Glu Ser Ser Met Val Leu Gly Tyr Trp Asp Ile Arg Gly 
1               5                   10                  15      


Leu Ala His Ala Ile Arg Leu Leu Leu Glu Phe Thr Asp Thr Ser Tyr 
            20                  25                  30          


Glu Glu Lys Arg Tyr Thr Cys Gly Glu Ala Pro Asp Tyr Asp Arg Ser 
        35                  40                  45              


Gln Trp Leu Asp Val Lys Phe Lys Leu Asp Leu Asp Phe Pro Asn Leu 
    50                  55                  60                  


Pro Tyr Leu Leu Asp Gly Lys Asn Lys Ile Thr Gln Ser Asn Ala Ile 
65                  70                  75                  80  


Leu Arg Tyr Ile Ala Arg Lys His Asn Met Cys Gly Glu Thr Glu Glu 
                85                  90                  95      


Glu Lys Ile Arg Val Asp Ile Ile Glu Asn Gln Val Met Asp Phe Arg 
            100                 105                 110         


Thr Gln Leu Ile Arg Leu Cys Tyr Ser Ser Asp His Glu Lys Leu Lys 
        115                 120                 125             


Pro Gln Tyr Leu Glu Glu Leu Pro Gly Gln Leu Lys Gln Phe Ser Met 
    130                 135                 140                 


Phe Leu Gly Lys Phe Ser Trp Phe Ala Gly Glu Lys Leu Thr Phe Val 
145                 150                 155                 160 


Asp Phe Leu Thr Tyr Asp Ile Leu Asp Gln Asn Arg Ile Phe Asp Pro 
                165                 170                 175     


Lys Cys Leu Asp Glu Phe Pro Asn Leu Lys Ala Phe Met Cys Arg Phe 
            180                 185                 190         


Glu Ala Leu Glu Lys Ile Ala Ala Tyr Leu Gln Ser Asp Gln Phe Cys 
        195                 200                 205             


Lys Met Pro Ile Asn Asn Lys Met Ala Gln Trp Gly Asn Lys Pro Val 
    210                 215                 220                 


Cys 
225 


<210>  3526
<211>  432
<212>  PRT
<213>  homo sapiens

<400>  3526

Met Gly Pro Ala Gly Ser Leu Leu Gly Ser Gly Gln Met Gln Ile Thr 
1               5                   10                  15      


Leu Trp Gly Ser Leu Ala Ala Val Ala Ile Phe Phe Val Ile Thr Phe 
            20                  25                  30          


Leu Ile Phe Leu Cys Ser Ser Cys Asp Arg Glu Lys Lys Pro Arg Gln 
        35                  40                  45              


His Ser Gly Asp His Glu Asn Leu Met Asn Val Pro Ser Asp Lys Glu 
    50                  55                  60                  


Met Phe Ser Arg Ser Val Thr Ser Leu Ala Thr Asp Ala Pro Ala Ser 
65                  70                  75                  80  


Ser Glu Gln Asn Gly Ala Leu Thr Asn Gly Asp Ile Leu Ser Glu Asp 
                85                  90                  95      


Ser Thr Leu Thr Cys Met Gln His Tyr Glu Glu Val Gln Thr Ser Ala 
            100                 105                 110         


Ser Asp Leu Leu Asp Ser Gln Asp Ser Thr Gly Lys Pro Lys Cys His 
        115                 120                 125             


Gln Ser Arg Glu Leu Pro Arg Ile Pro Pro Glu Ser Ala Val Asp Thr 
    130                 135                 140                 


Met Leu Thr Ala Arg Ser Val Asp Gly Asp Gln Gly Leu Gly Met Glu 
145                 150                 155                 160 


Gly Pro Tyr Glu Val Leu Lys Asp Ser Ser Ser Gln Glu Asn Met Val 
                165                 170                 175     


Glu Asp Cys Leu Tyr Glu Thr Val Lys Glu Ile Lys Glu Val Ala Ala 
            180                 185                 190         


Ala Ala His Leu Glu Lys Gly His Ser Gly Lys Ala Lys Ser Thr Ser 
        195                 200                 205             


Ala Ser Lys Glu Leu Pro Gly Pro Gln Thr Glu Gly Lys Ala Glu Phe 
    210                 215                 220                 


Ala Glu Tyr Ala Ser Val Asp Arg Asn Lys Lys Cys Arg Gln Ser Val 
225                 230                 235                 240 


Asn Val Glu Ser Ile Leu Gly Asn Ser Cys Asp Pro Glu Glu Glu Ala 
                245                 250                 255     


Pro Pro Pro Val Pro Val Lys Leu Leu Asp Glu Asn Glu Asn Leu Gln 
            260                 265                 270         


Glu Lys Glu Gly Gly Glu Ala Glu Glu Ser Ala Thr Asp Thr Thr Ser 
        275                 280                 285             


Glu Thr Asn Lys Arg Phe Ser Ser Leu Ser Tyr Lys Ser Arg Glu Glu 
    290                 295                 300                 


Asp Pro Thr Leu Thr Glu Glu Glu Ile Ser Ala Met Tyr Ser Ser Val 
305                 310                 315                 320 


Asn Lys Pro Gly Gln Leu Val Asn Lys Ser Gly Gln Ser Leu Thr Val 
                325                 330                 335     


Pro Glu Ser Thr Tyr Thr Ser Ile Gln Gly Asp Pro Gln Arg Ser Pro 
            340                 345                 350         


Ser Ser Cys Asn Asp Leu Tyr Ala Thr Val Lys Asp Phe Glu Lys Thr 
        355                 360                 365             


Pro Asn Ser Thr Leu Pro Pro Ala Gly Arg Pro Ser Glu Glu Pro Glu 
    370                 375                 380                 


Pro Asp Tyr Glu Ala Ile Gln Thr Leu Asn Arg Glu Glu Glu Lys Ala 
385                 390                 395                 400 


Thr Leu Gly Thr Asn Gly His His Gly Leu Val Pro Lys Glu Asn Asp 
                405                 410                 415     


Tyr Glu Ser Ile Ser Asp Leu Gln Gln Gly Arg Asp Ile Thr Arg Leu 
            420                 425                 430         


<210>  3527
<211>  401
<212>  PRT
<213>  homo sapiens

<400>  3527

Met Ala Gln Arg Tyr Asp Glu Leu Pro His Tyr Gly Gly Met Asp Gly 
1               5                   10                  15      


Val Gly Val Pro Ala Ser Met Tyr Gly Asp Pro His Ala Pro Arg Pro 
            20                  25                  30          


Ile Pro Pro Val His His Leu Asn His Gly Pro Pro Leu His Ala Thr 
        35                  40                  45              


Gln His Tyr Gly Ala His Ala Pro His Pro Asn Val Met Pro Ala Ser 
    50                  55                  60                  


Met Gly Ser Ala Val Asn Asp Ala Leu Lys Arg Asp Lys Asp Ala Ile 
65                  70                  75                  80  


Tyr Gly His Pro Leu Phe Pro Leu Leu Ala Leu Val Phe Glu Lys Cys 
                85                  90                  95      


Glu Leu Ala Thr Cys Thr Pro Arg Glu Pro Gly Val Ala Gly Gly Asp 
            100                 105                 110         


Val Cys Ser Ser Asp Ser Phe Asn Glu Asp Ile Ala Val Phe Ala Lys 
        115                 120                 125             


Gln Val Arg Ala Glu Lys Pro Leu Phe Ser Ser Asn Pro Glu Leu Asp 
    130                 135                 140                 


Asn Leu Met Ile Gln Ala Ile Gln Val Leu Arg Phe His Leu Leu Glu 
145                 150                 155                 160 


Leu Glu Lys Val His Glu Leu Cys Asp Asn Phe Cys His Arg Tyr Ile 
                165                 170                 175     


Ser Cys Leu Lys Gly Lys Met Pro Ile Asp Leu Val Ile Asp Glu Arg 
            180                 185                 190         


Asp Gly Ser Ser Lys Ser Asp His Glu Glu Leu Ser Gly Ser Ser Thr 
        195                 200                 205             


Asn Leu Ala Asp His Asn Pro Ser Ser Trp Arg Asp His Asp Asp Ala 
    210                 215                 220                 


Thr Ser Thr His Ser Ala Gly Thr Pro Gly Pro Ser Ser Gly Gly His 
225                 230                 235                 240 


Ala Ser Gln Ser Gly Asp Asn Ser Ser Glu Gln Gly Asp Gly Leu Asp 
                245                 250                 255     


Asn Ser Val Ala Ser Pro Gly Thr Gly Asp Asp Asp Asp Pro Asp Lys 
            260                 265                 270         


Asp Lys Lys Arg Gln Lys Lys Arg Gly Ile Phe Pro Lys Val Ala Thr 
        275                 280                 285             


Asn Ile Met Arg Ala Trp Leu Phe Gln His Leu Thr His Pro Tyr Pro 
    290                 295                 300                 


Ser Glu Glu Gln Lys Lys Gln Leu Ala Gln Asp Thr Gly Leu Thr Ile 
305                 310                 315                 320 


Leu Gln Val Asn Asn Trp Phe Ile Asn Ala Arg Arg Arg Ile Val Gln 
                325                 330                 335     


Pro Met Ile Asp Gln Ser Asn Arg Ala Gly Phe Leu Leu Asp Pro Ser 
            340                 345                 350         


Val Ser Gln Gly Ala Ala Tyr Ser Pro Glu Gly Gln Pro Met Gly Ser 
        355                 360                 365             


Phe Val Leu Asp Gly Gln Gln His Met Gly Ile Arg Pro Ala Gly Pro 
    370                 375                 380                 


Met Ser Gly Met Gly Met Asn Met Gly Met Asp Gly Gln Trp His Tyr 
385                 390                 395                 400 


Met 
    


<210>  3528
<211>  776
<212>  PRT
<213>  homo sapiens

<400>  3528

Met Asn Pro Glu Glu Gln Ile Val Thr Trp Leu Ile Ser Leu Gly Val 
1               5                   10                  15      


Leu Glu Ser Pro Lys Lys Thr Ile Cys Asp Pro Glu Glu Phe Leu Lys 
            20                  25                  30          


Ser Ser Leu Lys Asn Gly Val Val Leu Cys Lys Leu Ile Asn Arg Leu 
        35                  40                  45              


Met Pro Gly Ser Val Glu Lys Phe Cys Leu Asp Pro Gln Thr Glu Ala 
    50                  55                  60                  


Asp Cys Ile Asn Asn Ile Asn Asp Phe Leu Lys Gly Cys Ala Thr Leu 
65                  70                  75                  80  


Gln Val Glu Ile Phe Asp Pro Asp Asp Leu Tyr Ser Gly Val Asn Phe 
                85                  90                  95      


Ser Lys Val Leu Ser Thr Leu Leu Ala Val Asn Lys Ala Thr Glu Asp 
            100                 105                 110         


Gln Leu Ser Glu Arg Pro Cys Gly Arg Ser Ser Ser Leu Ser Ala Ala 
        115                 120                 125             


Asn Thr Ser Gln Thr Asn Pro Gln Gly Ala Val Ser Ser Thr Val Ser 
    130                 135                 140                 


Gly Leu Gln Arg Gln Ser Lys Thr Val Glu Met Thr Glu Asn Gly Ser 
145                 150                 155                 160 


His Gln Leu Ile Val Lys Ala Arg Phe Asn Phe Lys Gln Thr Asn Glu 
                165                 170                 175     


Asp Glu Leu Ser Val Cys Lys Gly Asp Ile Ile Tyr Val Thr Arg Val 
            180                 185                 190         


Glu Glu Gly Gly Trp Trp Glu Gly Thr Leu Asn Gly Arg Thr Gly Trp 
        195                 200                 205             


Phe Pro Ser Asn Tyr Val Arg Glu Ile Lys Ser Ser Glu Arg Pro Leu 
    210                 215                 220                 


Ser Pro Lys Ala Val Lys Gly Phe Glu Thr Ala Pro Leu Thr Lys Asn 
225                 230                 235                 240 


Tyr Tyr Thr Val Val Leu Gln Asn Ile Leu Asp Thr Glu Lys Glu Tyr 
                245                 250                 255     


Ala Lys Glu Leu Gln Ser Leu Leu Val Thr Tyr Leu Arg Pro Leu Gln 
            260                 265                 270         


Ser Asn Asn Asn Leu Ser Thr Val Glu Val Thr Ser Leu Leu Gly Asn 
        275                 280                 285             


Phe Glu Glu Val Cys Thr Phe Gln Gln Thr Leu Cys Gln Ala Leu Glu 
    290                 295                 300                 


Glu Cys Ser Lys Phe Pro Glu Asn Gln His Lys Val Gly Gly Cys Leu 
305                 310                 315                 320 


Leu Ser Leu Met Pro His Phe Lys Ser Met Tyr Leu Ala Tyr Cys Ala 
                325                 330                 335     


Asn His Pro Ser Ala Val Asn Val Leu Thr Gln His Ser Asp Glu Leu 
            340                 345                 350         


Glu Gln Phe Met Glu Asn Gln Gly Ala Ser Ser Pro Gly Ile Leu Ile 
        355                 360                 365             


Leu Thr Thr Asn Leu Ser Lys Pro Phe Met Arg Leu Glu Lys Tyr Val 
    370                 375                 380                 


Thr Leu Leu Gln Glu Leu Glu Arg His Met Glu Asp Thr His Pro Asp 
385                 390                 395                 400 


His Gln Asp Ile Leu Lys Ala Ile Val Ala Phe Lys Thr Leu Met Gly 
                405                 410                 415     


Gln Cys Gln Asp Leu Arg Lys Arg Lys Gln Leu Glu Leu Gln Ile Leu 
            420                 425                 430         


Ser Glu Pro Ile Gln Ala Trp Glu Gly Glu Asp Ile Lys Asn Leu Gly 
        435                 440                 445             


Asn Val Ile Phe Met Ser Gln Val Met Val Gln Tyr Gly Ala Cys Glu 
    450                 455                 460                 


Glu Lys Glu Glu Arg Tyr Leu Met Leu Phe Ser Asn Val Leu Ile Met 
465                 470                 475                 480 


Leu Ser Ala Ser Pro Arg Met Ser Gly Phe Ile Tyr Gln Gly Lys Ile 
                485                 490                 495     


Pro Ile Ala Gly Thr Val Val Thr Arg Leu Asp Glu Ile Glu Gly Asn 
            500                 505                 510         


Asp Cys Thr Phe Glu Ile Thr Gly Asn Thr Val Glu Arg Ile Val Val 
        515                 520                 525             


His Cys Asn Asn Asn Gln Asp Phe Gln Glu Trp Leu Glu Gln Leu Asn 
    530                 535                 540                 


Arg Leu Ile Arg Gly Pro Ala Ser Cys Ser Ser Leu Ser Lys Thr Ser 
545                 550                 555                 560 


Ser Ser Ser Cys Ser Ala His Ser Ser Phe Ser Ser Thr Gly Gln Pro 
                565                 570                 575     


Arg Gly Pro Leu Glu Pro Pro Gln Ile Ile Lys Pro Trp Ser Leu Ser 
            580                 585                 590         


Cys Leu Arg Pro Ala Pro Pro Leu Arg Pro Ser Ala Ala Leu Gly Tyr 
        595                 600                 605             


Lys Glu Arg Met Ser Tyr Ile Leu Lys Glu Ser Ser Lys Ser Pro Lys 
    610                 615                 620                 


Thr Met Lys Lys Phe Leu His Lys Arg Lys Thr Glu Arg Lys Pro Ser 
625                 630                 635                 640 


Glu Glu Glu Tyr Val Ile Arg Lys Ser Thr Ala Ala Leu Glu Glu Asp 
                645                 650                 655     


Ala Gln Ile Leu Lys Val Ile Glu Ala Tyr Cys Thr Ser Ala Asn Phe 
            660                 665                 670         


Gln Gln Gly His Gly Ser Ser Thr Arg Lys Asp Ser Ile Pro Gln Val 
        675                 680                 685             


Leu Leu Pro Glu Glu Glu Lys Leu Ile Ile Glu Glu Thr Arg Ser Asn 
    690                 695                 700                 


Gly Gln Thr Ile Met Glu Glu Lys Ser Leu Val Asp Thr Val Tyr Ala 
705                 710                 715                 720 


Leu Lys Asp Glu Val Arg Glu Leu Lys Gln Glu Asn Lys Arg Met Lys 
                725                 730                 735     


Gln Cys Leu Glu Glu Glu Leu Lys Ser Arg Arg Asp Leu Glu Lys Leu 
            740                 745                 750         


Val Arg Arg Leu Leu Lys Gln Thr Asp Glu Cys Ile Arg Gly Glu Ser 
        755                 760                 765             


Ser Ser Lys Thr Ser Ile Leu Pro 
    770                 775     


<210>  3529
<211>  185
<212>  PRT
<213>  homo sapiens

<400>  3529

Met Val Lys Leu Gly Asn Asn Phe Ala Glu Lys Gly Thr Lys Gln Pro 
1               5                   10                  15      


Leu Leu Glu Asp Gly Phe Asp Thr Ile Pro Leu Met Thr Pro Leu Asp 
            20                  25                  30          


Val Asn Gln Leu Gln Phe Pro Pro Pro Asp Lys Val Val Val Lys Thr 
        35                  40                  45              


Lys Thr Glu Tyr Glu Pro Asp Arg Lys Lys Gly Lys Ala Arg Pro Pro 
    50                  55                  60                  


Gln Ile Ala Glu Phe Thr Val Ser Ile Thr Glu Gly Val Thr Glu Arg 
65                  70                  75                  80  


Phe Lys Val Ser Val Leu Val Leu Phe Ala Leu Ala Phe Leu Thr Cys 
                85                  90                  95      


Val Val Phe Leu Val Val Tyr Lys Val Tyr Lys Tyr Asp Arg Ala Cys 
            100                 105                 110         


Pro Asp Gly Phe Val Leu Lys Asn Thr Gln Cys Ile Pro Glu Gly Leu 
        115                 120                 125             


Glu Ser Tyr Tyr Ala Glu Gln Asp Ser Ser Ala Arg Glu Lys Phe Tyr 
    130                 135                 140                 


Thr Val Ile Asn His Tyr Asn Leu Ala Lys Gln Ser Ile Thr Arg Ser 
145                 150                 155                 160 


Val Ser Pro Trp Met Ser Val Leu Ser Glu Glu Lys Leu Ser Glu Gln 
                165                 170                 175     


Glu Thr Glu Ala Ala Glu Lys Ser Ala 
            180                 185 


<210>  3530
<211>  1047
<212>  PRT
<213>  homo sapiens

<400>  3530

Met Asp Ala Glu Ala Glu Asp Lys Thr Leu Arg Thr Arg Ser Lys Gly 
1               5                   10                  15      


Thr Glu Val Pro Met Asp Ser Leu Ile Gln Glu Leu Ser Val Ala Tyr 
            20                  25                  30          


Asp Cys Ser Met Ala Lys Lys Arg Thr Ala Glu Asp Gln Ala Leu Gly 
        35                  40                  45              


Val Pro Val Asn Lys Arg Lys Ser Leu Leu Met Lys Pro Arg His Tyr 
    50                  55                  60                  


Ser Pro Lys Ala Asp Cys Gln Glu Asp Arg Ser Asp Arg Thr Glu Asp 
65                  70                  75                  80  


Asp Gly Pro Leu Glu Thr His Gly His Ser Thr Ala Glu Glu Ile Met 
                85                  90                  95      


Ile Lys Pro Met Asp Glu Ser Leu Leu Ser Thr Ala Gln Glu Asn Ser 
            100                 105                 110         


Ser Arg Lys Glu Asp Arg Tyr Ser Cys Tyr Gln Glu Leu Met Val Lys 
        115                 120                 125             


Ser Leu Met His Leu Gly Lys Phe Glu Lys Asn Val Ser Val Gln Thr 
    130                 135                 140                 


Val Ser Glu Asn Leu Asn Asp Ser Gly Ile Gln Ser Leu Lys Ala Glu 
145                 150                 155                 160 


Ser Asp Glu Ala Asp Glu Cys Phe Leu Ile His Ser Asp Asp Gly Arg 
                165                 170                 175     


Asp Lys Ile Asp Asp Ser Gln Pro Pro Phe Cys Ser Ser Asp Asp Asn 
            180                 185                 190         


Glu Ser Asn Ser Glu Ser Ala Glu Asn Gly Trp Asp Ser Gly Ser Asn 
        195                 200                 205             


Phe Ser Glu Glu Thr Lys Pro Pro Arg Val Pro Lys Tyr Val Leu Thr 
    210                 215                 220                 


Asp His Lys Lys Asp Leu Leu Glu Val Pro Glu Ile Lys Thr Glu Gly 
225                 230                 235                 240 


Asp Lys Phe Ile Pro Cys Glu Asn Arg Cys Asp Ser Glu Thr Glu Arg 
                245                 250                 255     


Lys Asp Pro Gln Asn Ala Leu Ala Glu Pro Leu Asp Gly Asn Ala Gln 
            260                 265                 270         


Pro Ser Phe Pro Asp Val Glu Glu Glu Asp Ser Glu Ser Leu Ala Val 
        275                 280                 285             


Met Thr Glu Glu Gly Ser Asp Leu Glu Lys Ala Lys Gly Asn Leu Ser 
    290                 295                 300                 


Leu Leu Glu Gln Ala Ile Ala Leu Gln Ala Glu Arg Gly Cys Val Phe 
305                 310                 315                 320 


His Asn Thr Tyr Lys Glu Leu Asp Arg Phe Leu Leu Glu His Leu Ala 
                325                 330                 335     


Gly Glu Arg Arg Gln Thr Lys Val Ile Asp Met Gly Gly Arg Gln Ile 
            340                 345                 350         


Phe Asn Asn Lys His Ser Pro Arg Pro Glu Lys Arg Glu Thr Lys Cys 
        355                 360                 365             


Pro Ile Pro Gly Cys Asp Gly Thr Gly His Val Thr Gly Leu Tyr Pro 
    370                 375                 380                 


His His Arg Ser Leu Ser Gly Cys Pro His Lys Val Arg Val Pro Leu 
385                 390                 395                 400 


Glu Ile Leu Ala Met His Glu Asn Val Leu Lys Cys Pro Thr Pro Gly 
                405                 410                 415     


Cys Thr Gly Arg Gly His Val Asn Ser Asn Arg Asn Thr His Arg Ser 
            420                 425                 430         


Leu Ser Gly Cys Pro Ile Ala Ala Ala Glu Lys Leu Ala Met Ser Gln 
        435                 440                 445             


Asp Lys Asn Gln Leu Asp Ser Pro Gln Thr Gly Gln Cys Pro Asp Gln 
    450                 455                 460                 


Ala His Arg Thr Ser Leu Val Lys Gln Ile Glu Phe Asn Phe Pro Ser 
465                 470                 475                 480 


Gln Ala Ile Thr Ser Pro Arg Ala Thr Val Ser Lys Glu Gln Glu Lys 
                485                 490                 495     


Phe Gly Lys Val Pro Phe Asp Tyr Ala Ser Phe Asp Ala Gln Val Phe 
            500                 505                 510         


Gly Lys Arg Pro Leu Ile Gln Thr Val Gln Gly Arg Lys Thr Pro Pro 
        515                 520                 525             


Phe Pro Glu Ser Lys His Phe Pro Asn Pro Val Lys Phe Pro Asn Arg 
    530                 535                 540                 


Leu Pro Ser Ala Gly Ala His Thr Gln Ser Pro Gly Arg Ala Ser Ser 
545                 550                 555                 560 


Tyr Ser Tyr Gly Gln Cys Ser Glu Asp Thr His Ile Ala Ala Ala Ala 
                565                 570                 575     


Ala Ile Leu Asn Leu Ser Thr Arg Cys Arg Glu Ala Thr Asp Ile Leu 
            580                 585                 590         


Ser Asn Lys Pro Gln Ser Leu His Ala Lys Gly Ala Glu Ile Glu Val 
        595                 600                 605             


Asp Glu Asn Gly Thr Leu Asp Leu Ser Met Lys Lys Asn Arg Ile Leu 
    610                 615                 620                 


Asp Lys Ser Ala Pro Leu Thr Ser Ser Asn Thr Ser Ile Pro Thr Pro 
625                 630                 635                 640 


Ser Ser Ser Pro Phe Lys Thr Ser Ser Ile Leu Val Asn Ala Ala Phe 
                645                 650                 655     


Tyr Gln Ala Leu Cys Asp Gln Glu Gly Trp Asp Thr Pro Ile Asn Tyr 
            660                 665                 670         


Ser Lys Thr His Gly Lys Thr Glu Glu Glu Lys Glu Lys Asp Pro Val 
        675                 680                 685             


Ser Ser Leu Glu Asn Leu Glu Glu Lys Lys Phe Pro Gly Glu Ala Ser 
    690                 695                 700                 


Ile Pro Ser Pro Lys Pro Lys Leu His Ala Arg Asp Leu Lys Lys Glu 
705                 710                 715                 720 


Leu Ile Thr Cys Pro Thr Pro Gly Cys Asp Gly Ser Gly His Val Thr 
                725                 730                 735     


Gly Asn Tyr Ala Ser His Arg Ser Val Ser Gly Cys Pro Leu Ala Asp 
            740                 745                 750         


Lys Thr Leu Lys Ser Leu Met Ala Ala Asn Ser Gln Glu Leu Lys Cys 
        755                 760                 765             


Pro Thr Pro Gly Cys Asp Gly Ser Gly His Val Thr Gly Asn Tyr Ala 
    770                 775                 780                 


Ser His Arg Ser Leu Ser Gly Cys Pro Arg Ala Arg Lys Gly Gly Val 
785                 790                 795                 800 


Lys Met Thr Pro Thr Lys Glu Glu Lys Glu Asp Pro Glu Leu Lys Cys 
                805                 810                 815     


Pro Val Ile Gly Cys Asp Gly Gln Gly His Ile Ser Gly Lys Tyr Thr 
            820                 825                 830         


Ser His Arg Thr Ala Ser Gly Cys Pro Leu Ala Ala Lys Arg Gln Lys 
        835                 840                 845             


Glu Asn Pro Leu Asn Gly Ala Ser Leu Ser Trp Lys Leu Asn Lys Gln 
    850                 855                 860                 


Glu Leu Pro His Cys Pro Leu Pro Gly Cys Asn Gly Leu Gly His Val 
865                 870                 875                 880 


Asn Asn Val Phe Val Thr His Arg Ser Leu Ser Gly Cys Pro Leu Asn 
                885                 890                 895     


Ala Gln Val Ile Lys Lys Gly Lys Val Ser Glu Glu Leu Met Thr Ile 
            900                 905                 910         


Lys Leu Lys Ala Thr Gly Gly Ile Glu Ser Asp Glu Glu Ile Arg His 
        915                 920                 925             


Leu Asp Glu Glu Ile Lys Glu Leu Asn Glu Ser Asn Leu Lys Ile Glu 
    930                 935                 940                 


Ala Asp Met Met Lys Leu Gln Thr Gln Ile Thr Ser Met Glu Ser Asn 
945                 950                 955                 960 


Leu Lys Thr Ile Glu Glu Glu Asn Lys Leu Ile Glu Gln Asn Asn Glu 
                965                 970                 975     


Ser Leu Leu Lys Glu Leu Ala Gly Leu Ser Gln Ala Leu Ile Ser Ser 
            980                 985                 990         


Leu Ala Asp Ile Gln Leu Pro Gln  Met Gly Pro Ile Ser  Glu Gln Asn 
        995                 1000                 1005             


Phe Glu  Ala Tyr Val Asn Thr  Leu Thr Asp Met Tyr  Ser Asn Leu 
    1010                 1015                 1020             


Glu Arg  Asp Tyr Ser Pro Glu  Cys Lys Ala Leu Leu  Glu Ser Ile 
    1025                 1030                 1035             


Lys Gln  Ala Val Lys Gly Ile  His Val 
    1040                 1045         


<210>  3531
<211>  79
<212>  PRT
<213>  homo sapiens

<400>  3531

Met Ala Arg Ser Arg Leu Thr Ala Thr Ser Val Ser Gln Val Gln Glu 
1               5                   10                  15      


Asn Gly Phe Val Lys Lys Leu Glu Pro Lys Ser Gly Trp Met Thr Phe 
            20                  25                  30          


Leu Glu Val Thr Gly Lys Ile Cys Glu Met Leu Phe Cys Pro Glu Ala 
        35                  40                  45              


Ile Leu Leu Thr Arg Lys Asp Thr Pro Tyr Cys Glu Thr Gly Leu Ile 
    50                  55                  60                  


Phe Leu Thr Leu Thr Lys Thr Ile Ala Asn Thr Tyr Phe Tyr Phe 
65                  70                  75                  


<210>  3532
<211>  710
<212>  PRT
<213>  homo sapiens

<400>  3532

Met Glu Glu Met Glu Glu Glu Leu Lys Cys Pro Val Cys Gly Ser Phe 
1               5                   10                  15      


Tyr Arg Glu Pro Ile Ile Leu Pro Cys Ser His Asn Leu Cys Gln Ala 
            20                  25                  30          


Cys Ala Arg Asn Ile Leu Val Gln Thr Pro Glu Ser Glu Ser Pro Gln 
        35                  40                  45              


Ser His Arg Ala Ala Gly Ser Gly Val Ser Asp Tyr Asp Tyr Leu Asp 
    50                  55                  60                  


Leu Asp Lys Met Ser Leu Tyr Ser Glu Ala Asp Ser Gly Tyr Gly Ser 
65                  70                  75                  80  


Tyr Gly Gly Phe Ala Ser Ala Pro Thr Thr Pro Cys Gln Lys Ser Pro 
                85                  90                  95      


Asn Gly Val Arg Val Phe Pro Pro Ala Met Pro Pro Pro Ala Thr His 
            100                 105                 110         


Leu Ser Pro Ala Leu Ala Pro Val Pro Arg Asn Ser Cys Ile Thr Cys 
        115                 120                 125             


Pro Gln Cys His Arg Ser Leu Ile Leu Asp Asp Arg Gly Leu Arg Gly 
    130                 135                 140                 


Phe Pro Lys Asn Arg Val Leu Glu Gly Val Ile Asp Arg Tyr Gln Gln 
145                 150                 155                 160 


Ser Lys Ala Ala Ala Leu Lys Cys Gln Leu Cys Glu Lys Ala Pro Lys 
                165                 170                 175     


Glu Ala Thr Val Met Cys Glu Gln Cys Asp Val Phe Tyr Cys Asp Pro 
            180                 185                 190         


Cys Arg Leu Arg Cys His Pro Pro Arg Gly Pro Leu Ala Lys His Arg 
        195                 200                 205             


Leu Val Pro Pro Ala Gln Gly Arg Val Ser Arg Arg Leu Ser Pro Arg 
    210                 215                 220                 


Lys Val Ser Thr Cys Thr Asp His Glu Leu Glu Asn His Ser Met Tyr 
225                 230                 235                 240 


Cys Val Gln Cys Lys Met Pro Val Cys Tyr Gln Cys Leu Glu Glu Gly 
                245                 250                 255     


Lys His Ser Ser His Glu Val Lys Ala Leu Gly Ala Met Trp Lys Leu 
            260                 265                 270         


His Lys Ser Gln Leu Ser Gln Ala Leu Asn Gly Leu Ser Asp Arg Ala 
        275                 280                 285             


Lys Glu Ala Lys Glu Phe Leu Val Gln Leu Arg Asn Met Val Gln Gln 
    290                 295                 300                 


Ile Gln Glu Asn Ser Val Glu Phe Glu Ala Cys Leu Val Ala Gln Cys 
305                 310                 315                 320 


Asp Ala Leu Ile Asp Ala Leu Asn Arg Arg Lys Ala Gln Leu Leu Ala 
                325                 330                 335     


Arg Val Asn Lys Glu His Glu His Lys Leu Lys Val Val Arg Asp Gln 
            340                 345                 350         


Ile Ser His Cys Thr Val Lys Leu Arg Gln Thr Thr Gly Leu Met Glu 
        355                 360                 365             


Tyr Cys Leu Glu Val Ile Lys Glu Asn Asp Pro Ser Gly Phe Leu Gln 
    370                 375                 380                 


Ile Ser Asp Ala Leu Ile Arg Arg Val His Leu Thr Glu Asp Gln Trp 
385                 390                 395                 400 


Gly Lys Gly Thr Leu Thr Pro Arg Met Thr Thr Asp Phe Asp Leu Ser 
                405                 410                 415     


Leu Asp Asn Ser Pro Leu Leu Gln Ser Ile His Gln Leu Asp Phe Val 
            420                 425                 430         


Gln Val Lys Ala Ser Ser Pro Val Pro Ala Thr Pro Ile Leu Gln Leu 
        435                 440                 445             


Glu Glu Cys Cys Thr His Asn Asn Ser Ala Thr Leu Ser Trp Lys Gln 
    450                 455                 460                 


Pro Pro Leu Ser Thr Val Pro Ala Asp Gly Tyr Ile Leu Glu Leu Asp 
465                 470                 475                 480 


Asp Gly Asn Gly Gly Gln Phe Arg Glu Val Tyr Val Gly Lys Glu Thr 
                485                 490                 495     


Met Cys Thr Val Asp Gly Leu His Phe Asn Ser Thr Tyr Asn Ala Arg 
            500                 505                 510         


Val Lys Ala Phe Asn Lys Thr Gly Val Ser Pro Tyr Ser Lys Thr Leu 
        515                 520                 525             


Val Leu Gln Thr Ser Glu Val Ala Trp Phe Ala Phe Asp Pro Gly Ser 
    530                 535                 540                 


Ala His Ser Asp Ile Ile Leu Ser Asn Asp Asn Leu Thr Val Thr Cys 
545                 550                 555                 560 


Ser Ser Tyr Asp Asp Arg Val Val Leu Gly Lys Thr Gly Phe Ser Lys 
                565                 570                 575     


Gly Ile His Tyr Trp Glu Leu Thr Val Asp Arg Tyr Asp Asn His Pro 
            580                 585                 590         


Asp Pro Ala Phe Gly Val Ala Arg Met Asp Val Met Lys Asp Val Met 
        595                 600                 605             


Leu Gly Lys Asp Asp Lys Ala Trp Ala Met Tyr Val Asp Asn Asn Arg 
    610                 615                 620                 


Ser Trp Phe Met His Asn Asn Ser His Thr Asn Arg Thr Glu Gly Gly 
625                 630                 635                 640 


Ile Thr Lys Gly Ala Thr Ile Gly Val Leu Leu Asp Leu Asn Arg Lys 
                645                 650                 655     


Asn Leu Thr Phe Phe Ile Asn Asp Glu Gln Gln Gly Pro Ile Ala Phe 
            660                 665                 670         


Asp Asn Val Glu Gly Leu Phe Phe Pro Ala Val Ser Leu Asn Arg Asn 
        675                 680                 685             


Val Gln Val Thr Leu His Thr Gly Leu Pro Val Pro Asp Phe Tyr Ser 
    690                 695                 700                 


Ser Arg Ala Ser Ile Ala 
705                 710 


<210>  3533
<211>  1294
<212>  PRT
<213>  homo sapiens

<400>  3533

Met Pro Tyr Glu Val Asn Ala Gly Tyr Asp Phe Thr Asn Met Val Arg 
1               5                   10                  15      


Lys Lys Asn Pro Pro Leu Arg Asn Val Ala Ser Glu Gly Glu Gly Gln 
            20                  25                  30          


Ile Leu Glu Pro Ile Gly Thr Glu Ser Lys Val Ser Gly Lys Asn Lys 
        35                  40                  45              


Glu Phe Ser Ala Asp Gln Met Ser Glu Asn Thr Asp Gln Ser Asp Ala 
    50                  55                  60                  


Ala Glu Leu Asn His Lys Glu Glu His Ser Leu His Val Gln Asp Pro 
65                  70                  75                  80  


Ser Ser Ser Ser Lys Lys Asp Leu Lys Ser Ala Val Leu Ser Glu Lys 
                85                  90                  95      


Ala Gly Phe Asn Tyr Glu Ser Pro Ser Lys Gly Gly Asn Phe Pro Ser 
            100                 105                 110         


Phe Pro His Asp Glu Val Thr Asp Arg Asn Met Leu Ala Phe Ser Ser 
        115                 120                 125             


Pro Ala Ala Gly Gly Val Cys Glu Pro Leu Lys Ser Pro Gln Arg Ala 
    130                 135                 140                 


Glu Ala Asp Asp Pro Gln Asp Met Ala Cys Thr Pro Ser Gly Asp Ser 
145                 150                 155                 160 


Leu Glu Thr Lys Glu Asp Gln Lys Met Ser Pro Lys Ala Thr Glu Glu 
                165                 170                 175     


Thr Gly Gln Ala Gln Ser Gly Gln Ala Asn Cys Gln Gly Leu Ser Pro 
            180                 185                 190         


Val Ser Val Ala Ser Lys Asn Pro Gln Val Pro Ser Asp Gly Gly Val 
        195                 200                 205             


Arg Leu Asn Lys Ser Lys Thr Asp Leu Leu Val Asn Asp Asn Pro Asp 
    210                 215                 220                 


Pro Ala Pro Leu Ser Pro Glu Leu Gln Asp Phe Lys Cys Asn Ile Cys 
225                 230                 235                 240 


Gly Tyr Gly Tyr Tyr Gly Asn Asp Pro Thr Asp Leu Ile Lys His Phe 
                245                 250                 255     


Arg Lys Tyr His Leu Gly Leu His Asn Arg Thr Arg Gln Asp Ala Glu 
            260                 265                 270         


Leu Asp Ser Lys Ile Leu Ala Leu His Asn Met Val Gln Phe Ser His 
        275                 280                 285             


Ser Lys Asp Phe Gln Lys Val Asn Arg Ser Val Phe Ser Gly Val Leu 
    290                 295                 300                 


Gln Asp Ile Asn Ser Ser Arg Pro Val Leu Leu Asn Gly Thr Tyr Asp 
305                 310                 315                 320 


Val Gln Val Thr Ser Gly Gly Thr Phe Ile Gly Ile Gly Arg Lys Thr 
                325                 330                 335     


Pro Asp Cys Gln Gly Asn Thr Lys Tyr Phe Arg Cys Lys Phe Cys Asn 
            340                 345                 350         


Phe Thr Tyr Met Gly Asn Ser Ser Thr Glu Leu Glu Gln His Phe Leu 
        355                 360                 365             


Gln Thr His Pro Asn Lys Ile Lys Ala Ser Leu Pro Ser Ser Glu Val 
    370                 375                 380                 


Ala Lys Pro Ser Glu Lys Asn Ser Asn Lys Ser Ile Pro Ala Leu Gln 
385                 390                 395                 400 


Ser Ser Asp Ser Gly Asp Leu Gly Lys Trp Gln Asp Lys Ile Thr Val 
                405                 410                 415     


Lys Ala Gly Asp Asp Thr Pro Val Gly Tyr Ser Val Pro Ile Lys Pro 
            420                 425                 430         


Leu Asp Ser Ser Arg Gln Asn Gly Thr Glu Ala Thr Ser Tyr Tyr Trp 
        435                 440                 445             


Cys Lys Phe Cys Ser Phe Ser Cys Glu Ser Ser Ser Ser Leu Lys Leu 
    450                 455                 460                 


Leu Glu His Tyr Gly Lys Gln His Gly Ala Val Gln Ser Gly Gly Leu 
465                 470                 475                 480 


Asn Pro Glu Leu Asn Asp Lys Leu Ser Arg Gly Ser Val Ile Asn Gln 
                485                 490                 495     


Asn Asp Leu Ala Lys Ser Ser Glu Gly Glu Thr Met Thr Lys Thr Asp 
            500                 505                 510         


Lys Ser Ser Ser Gly Ala Lys Lys Lys Asp Phe Ser Ser Lys Gly Ala 
        515                 520                 525             


Glu Asp Asn Met Val Thr Ser Tyr Asn Cys Gln Phe Cys Asp Phe Arg 
    530                 535                 540                 


Tyr Ser Lys Ser His Gly Pro Asp Val Ile Val Val Gly Pro Leu Leu 
545                 550                 555                 560 


Arg His Tyr Gln Gln Leu His Asn Ile His Lys Cys Thr Ile Lys His 
                565                 570                 575     


Cys Pro Phe Cys Pro Arg Gly Leu Cys Ser Pro Glu Lys His Leu Gly 
            580                 585                 590         


Glu Ile Thr Tyr Pro Phe Ala Cys Arg Lys Ser Asn Cys Ser His Cys 
        595                 600                 605             


Ala Leu Leu Leu Leu His Leu Ser Pro Gly Ala Ala Gly Ser Ser Arg 
    610                 615                 620                 


Val Lys His Gln Cys His Gln Cys Ser Phe Thr Thr Pro Asp Val Asp 
625                 630                 635                 640 


Val Leu Leu Phe His Tyr Glu Ser Val His Glu Ser Gln Ala Ser Asp 
                645                 650                 655     


Val Lys Gln Glu Ala Asn His Leu Gln Gly Ser Asp Gly Gln Gln Ser 
            660                 665                 670         


Val Lys Glu Ser Lys Glu His Ser Cys Thr Lys Cys Asp Phe Ile Thr 
        675                 680                 685             


Gln Val Glu Glu Glu Ile Ser Arg His Tyr Arg Arg Ala His Ser Cys 
    690                 695                 700                 


Tyr Lys Cys Arg Gln Cys Ser Phe Thr Ala Ala Asp Thr Gln Ser Leu 
705                 710                 715                 720 


Leu Glu His Phe Asn Thr Val His Cys Gln Glu Gln Asp Ile Thr Thr 
                725                 730                 735     


Ala Asn Gly Glu Glu Asp Gly His Ala Ile Ser Thr Ile Lys Glu Glu 
            740                 745                 750         


Pro Lys Ile Asp Phe Arg Val Tyr Asn Leu Leu Thr Pro Asp Ser Lys 
        755                 760                 765             


Met Gly Glu Pro Val Ser Glu Ser Val Val Lys Arg Glu Lys Leu Glu 
    770                 775                 780                 


Glu Lys Asp Gly Leu Lys Glu Lys Val Trp Thr Glu Ser Ser Ser Asp 
785                 790                 795                 800 


Asp Leu Arg Asn Val Thr Trp Arg Gly Ala Asp Ile Leu Arg Gly Ser 
                805                 810                 815     


Pro Ser Tyr Thr Gln Ala Ser Leu Gly Leu Leu Thr Pro Val Ser Gly 
            820                 825                 830         


Thr Gln Glu Gln Thr Lys Thr Leu Arg Asp Ser Pro Asn Val Glu Ala 
        835                 840                 845             


Ala His Leu Ala Arg Pro Ile Tyr Gly Leu Ala Val Glu Thr Lys Gly 
    850                 855                 860                 


Phe Leu Gln Gly Ala Pro Ala Gly Gly Glu Lys Ser Gly Ala Leu Pro 
865                 870                 875                 880 


Gln Gln Tyr Pro Ala Ser Gly Glu Asn Lys Ser Lys Asp Glu Ser Gln 
                885                 890                 895     


Ser Leu Leu Arg Arg Arg Arg Gly Ser Gly Val Phe Cys Ala Asn Cys 
            900                 905                 910         


Leu Thr Thr Lys Thr Ser Leu Trp Arg Lys Asn Ala Asn Gly Gly Tyr 
        915                 920                 925             


Val Cys Asn Ala Cys Gly Leu Tyr Gln Lys Leu His Ser Thr Pro Arg 
    930                 935                 940                 


Pro Leu Asn Ile Ile Lys Gln Asn Asn Gly Glu Gln Ile Ile Arg Arg 
945                 950                 955                 960 


Arg Thr Arg Lys Arg Leu Asn Pro Glu Ala Leu Gln Ala Glu Gln Leu 
                965                 970                 975     


Asn Lys Gln Gln Arg Gly Ser Asn Glu Glu Gln Val Asn Gly Ser Pro 
            980                 985                 990         


Leu Glu Arg Arg Ser Glu Asp His  Leu Thr Glu Ser His  Gln Arg Glu 
        995                 1000                 1005             


Ile Pro  Leu Pro Ser Leu Ser  Lys Tyr Glu Ala Gln  Gly Ser Leu 
    1010                 1015                 1020             


Thr Lys  Ser His Ser Ala Gln  Gln Pro Val Leu Val  Ser Gln Thr 
    1025                 1030                 1035             


Leu Asp  Ile His Lys Arg Met  Gln Pro Leu His Ile  Gln Ile Lys 
    1040                 1045                 1050             


Ser Pro  Gln Glu Ser Thr Gly  Asp Pro Gly Asn Ser  Ser Ser Val 
    1055                 1060                 1065             


Ser Glu  Gly Lys Gly Ser Ser  Glu Arg Gly Ser Pro  Ile Glu Lys 
    1070                 1075                 1080             


Tyr Met  Arg Pro Ala Lys His  Pro Asn Tyr Ser Pro  Pro Gly Ser 
    1085                 1090                 1095             


Pro Ile  Glu Lys Tyr Gln Tyr  Pro Leu Phe Gly Leu  Pro Phe Val 
    1100                 1105                 1110             


His Asn  Asp Phe Gln Ser Glu  Ala Asp Trp Leu Arg  Phe Trp Ser 
    1115                 1120                 1125             


Lys Tyr  Lys Leu Ser Val Pro  Gly Asn Pro His Tyr  Leu Ser His 
    1130                 1135                 1140             


Val Pro  Gly Leu Pro Asn Pro  Cys Gln Asn Tyr Val  Pro Tyr Pro 
    1145                 1150                 1155             


Thr Phe  Asn Leu Pro Pro His  Phe Ser Ala Val Gly  Ser Asp Asn 
    1160                 1165                 1170             


Asp Ile  Pro Leu Asp Leu Ala  Ile Lys His Ser Arg  Pro Gly Pro 
    1175                 1180                 1185             


Thr Ala  Asn Gly Ala Ser Lys  Glu Lys Thr Lys Ala  Pro Pro Asn 
    1190                 1195                 1200             


Val Lys  Asn Glu Gly Pro Leu  Asn Val Val Lys Thr  Glu Lys Val 
    1205                 1210                 1215             


Asp Arg  Ser Thr Gln Asp Glu  Leu Ser Thr Lys Cys  Val His Cys 
    1220                 1225                 1230             


Gly Ile  Val Phe Leu Asp Glu  Val Met Tyr Ala Leu  His Met Ser 
    1235                 1240                 1245             


Cys His  Gly Asp Ser Gly Pro  Phe Gln Cys Ser Ile  Cys Gln His 
    1250                 1255                 1260             


Leu Cys  Thr Asp Lys Tyr Asp  Phe Thr Thr His Ile  Gln Arg Gly 
    1265                 1270                 1275             


Leu His  Arg Asn Asn Ala Gln  Val Glu Lys Asn Gly  Lys Pro Lys 
    1280                 1285                 1290             


Glu 
    


<210>  3534
<211>  537
<212>  PRT
<213>  homo sapiens

<400>  3534

Met Pro Ala Pro Thr Gln Leu Phe Phe Pro Leu Ile Arg Asn Cys Glu 
1               5                   10                  15      


Leu Ser Arg Ile Tyr Gly Thr Ala Cys Tyr Cys His His Lys His Leu 
            20                  25                  30          


Cys Cys Ser Ser Ser Tyr Ile Pro Gln Ser Arg Leu Arg Tyr Thr Pro 
        35                  40                  45              


His Pro Ala Tyr Ala Thr Phe Cys Arg Pro Lys Glu Asn Trp Trp Gln 
    50                  55                  60                  


Tyr Thr Gln Gly Arg Arg Tyr Ala Ser Thr Pro Gln Lys Phe Tyr Leu 
65                  70                  75                  80  


Thr Pro Pro Gln Val Asn Ser Ile Leu Lys Ala Asn Glu Tyr Ser Phe 
                85                  90                  95      


Lys Val Pro Glu Phe Asp Gly Lys Asn Val Ser Ser Ile Leu Gly Phe 
            100                 105                 110         


Asp Ser Asn Gln Leu Pro Ala Asn Ala Pro Ile Glu Asp Arg Arg Ser 
        115                 120                 125             


Ala Ala Thr Cys Leu Gln Thr Arg Gly Met Leu Leu Gly Val Phe Asp 
    130                 135                 140                 


Gly His Ala Gly Cys Ala Cys Ser Gln Ala Val Ser Glu Arg Leu Phe 
145                 150                 155                 160 


Tyr Tyr Ile Ala Val Ser Leu Leu Pro His Glu Thr Leu Leu Glu Ile 
                165                 170                 175     


Glu Asn Ala Val Glu Ser Gly Arg Ala Leu Leu Pro Ile Leu Gln Trp 
            180                 185                 190         


His Lys His Pro Asn Asp Tyr Phe Ser Lys Glu Ala Ser Lys Leu Tyr 
        195                 200                 205             


Phe Asn Ser Leu Arg Thr Tyr Trp Gln Glu Leu Ile Asp Leu Asn Thr 
    210                 215                 220                 


Gly Glu Ser Thr Asp Ile Asp Val Lys Glu Ala Leu Ile Asn Ala Phe 
225                 230                 235                 240 


Lys Arg Leu Asp Asn Asp Ile Ser Leu Glu Ala Gln Val Gly Asp Pro 
                245                 250                 255     


Asn Ser Phe Leu Asn Tyr Leu Val Leu Arg Val Ala Phe Ser Gly Ala 
            260                 265                 270         


Thr Ala Cys Val Ala His Val Asp Gly Val Asp Leu His Val Ala Asn 
        275                 280                 285             


Thr Gly Asp Ser Arg Ala Met Leu Gly Val Gln Glu Glu Asp Gly Ser 
    290                 295                 300                 


Trp Ser Ala Val Thr Leu Ser Asn Asp His Asn Ala Gln Asn Glu Arg 
305                 310                 315                 320 


Glu Leu Glu Arg Leu Lys Leu Glu His Pro Lys Ser Glu Ala Lys Ser 
                325                 330                 335     


Val Val Lys Gln Asp Arg Leu Leu Gly Leu Leu Met Pro Phe Arg Ala 
            340                 345                 350         


Phe Gly Asp Val Lys Phe Lys Trp Ser Ile Asp Leu Gln Lys Arg Val 
        355                 360                 365             


Ile Glu Ser Gly Pro Asp Gln Leu Asn Asp Asn Glu Tyr Thr Lys Phe 
    370                 375                 380                 


Ile Pro Pro Asn Tyr His Thr Pro Pro Tyr Leu Thr Ala Glu Pro Glu 
385                 390                 395                 400 


Val Thr Tyr His Arg Leu Arg Pro Gln Asp Lys Phe Leu Val Leu Ala 
                405                 410                 415     


Thr Asp Gly Leu Trp Glu Thr Met His Arg Gln Asp Val Val Arg Ile 
            420                 425                 430         


Val Gly Glu Tyr Leu Thr Gly Met His His Gln Gln Pro Ile Ala Val 
        435                 440                 445             


Gly Gly Tyr Lys Val Thr Leu Gly Gln Met His Gly Leu Leu Thr Glu 
    450                 455                 460                 


Arg Arg Thr Lys Met Ser Ser Val Phe Glu Asp Gln Asn Ala Ala Thr 
465                 470                 475                 480 


His Leu Ile Arg His Ala Val Gly Asn Asn Glu Phe Gly Thr Val Asp 
                485                 490                 495     


His Glu Arg Leu Ser Lys Met Leu Ser Leu Pro Glu Glu Leu Ala Arg 
            500                 505                 510         


Met Tyr Arg Asp Asp Ile Thr Ile Ile Val Val Gln Phe Asn Ser His 
        515                 520                 525             


Val Val Gly Ala Tyr Gln Asn Gln Glu 
    530                 535         


<210>  3535
<211>  315
<212>  PRT
<213>  homo sapiens

<400>  3535

Met Ala Leu Pro Phe Gln Lys Glu Leu Glu Lys Tyr Lys Asn Ile Asp 
1               5                   10                  15      


Glu Asp Glu Leu Leu Gly Lys Leu Ser Glu Glu Glu Leu Lys Gln Leu 
            20                  25                  30          


Glu Asn Val Leu Asp Asp Leu Asp Pro Glu Ser Ala Met Leu Pro Ala 
        35                  40                  45              


Gly Phe Arg Gln Lys Asp Gln Thr Gln Lys Ala Ala Thr Gly Pro Phe 
    50                  55                  60                  


Asp Arg Glu His Leu Leu Met Tyr Leu Glu Lys Glu Ala Leu Glu Gln 
65                  70                  75                  80  


Lys Asp Arg Glu Asp Phe Val Pro Phe Thr Gly Glu Lys Lys Gly Arg 
                85                  90                  95      


Val Phe Ile Pro Lys Glu Lys Pro Ile Glu Thr Arg Lys Glu Glu Lys 
            100                 105                 110         


Val Thr Leu Asp Pro Glu Leu Glu Glu Ala Leu Ala Ser Ala Ser Asp 
        115                 120                 125             


Thr Glu Leu Tyr Asp Leu Ala Ala Val Leu Gly Val His Asn Leu Leu 
    130                 135                 140                 


Asn Asn Pro Lys Phe Asp Glu Glu Thr Ala Asn Asn Lys Gly Gly Lys 
145                 150                 155                 160 


Gly Pro Val Arg Asn Val Val Lys Gly Glu Lys Val Lys Pro Val Phe 
                165                 170                 175     


Glu Glu Pro Pro Asn Pro Thr Asn Val Glu Ile Ser Leu Gln Gln Met 
            180                 185                 190         


Lys Ala Asn Asp Pro Ser Leu Gln Glu Val Asn Leu Asn Asn Ile Lys 
        195                 200                 205             


Ala Phe Ala Asp Met Leu Lys Val Asn Lys Thr Leu Thr Ser Leu Asn 
    210                 215                 220                 


Ile Glu Ser Asn Phe Ile Thr Gly Thr Gly Ile Leu Ala Leu Val Glu 
225                 230                 235                 240 


Ala Leu Lys Glu Asn Asp Thr Leu Thr Glu Ile Lys Ile Asp Asn Gln 
                245                 250                 255     


Arg Gln Gln Leu Gly Thr Ala Val Glu Met Glu Ile Ala Gln Met Leu 
            260                 265                 270         


Glu Glu Asn Ser Arg Ile Leu Lys Phe Gly Tyr Gln Phe Thr Lys Gln 
        275                 280                 285             


Gly Pro Arg Thr Arg Val Ala Ala Ala Ile Thr Lys Asn Asn Asp Leu 
    290                 295                 300                 


Val Arg Lys Lys Arg Val Glu Ala Asp Arg Arg 
305                 310                 315 


<210>  3536
<211>  484
<212>  PRT
<213>  homo sapiens

<400>  3536

Met Phe Pro Asn Ser Ile Leu Gly Arg Pro Pro Phe Thr Pro Asn His 
1               5                   10                  15      


Gln Gln His Asn Asn Phe Phe Thr Leu Ser Pro Thr Val Tyr Ser His 
            20                  25                  30          


Gln Gln Leu Ile Asp Ala Gln Phe Asn Phe Gln Asn Ala Asp Leu Ser 
        35                  40                  45              


Arg Ala Val Ser Leu Gln Gln Leu Thr Tyr Gly Asn Val Ser Pro Ile 
    50                  55                  60                  


Gln Thr Ser Ala Ser Pro Leu Phe Arg Gly Arg Lys Arg Leu Ser Asp 
65                  70                  75                  80  


Glu Lys Asn Leu Pro Leu Asp Gly Lys Arg Gln Arg Phe His Ser Pro 
                85                  90                  95      


His Gln Glu Pro Thr Val Val Asn Gln Ile Val Pro Leu Ser Gly Glu 
            100                 105                 110         


Arg Arg Tyr Ser Met Pro Pro Leu Phe His Thr His Tyr Val Pro Asp 
        115                 120                 125             


Ile Val Arg Cys Val Pro Pro Phe Arg Glu Ile Ala Phe Leu Glu Pro 
    130                 135                 140                 


Arg Glu Ile Thr Leu Pro Glu Ala Lys Asp Lys Leu Ser Gln Gln Ile 
145                 150                 155                 160 


Leu Glu Leu Phe Glu Thr Cys Gln Gln Gln Ile Ser Asp Leu Lys Lys 
                165                 170                 175     


Lys Glu Leu Cys Arg Thr Gln Leu Gln Arg Glu Ile Gln Leu Leu Phe 
            180                 185                 190         


Pro Gln Ser Arg Leu Phe Leu Val Gly Ser Ser Leu Asn Gly Phe Gly 
        195                 200                 205             


Thr Arg Ser Ser Asp Gly Asp Leu Cys Leu Val Val Lys Glu Glu Pro 
    210                 215                 220                 


Cys Phe Phe Gln Val Asn Gln Lys Thr Glu Ala Arg His Ile Leu Thr 
225                 230                 235                 240 


Leu Val His Lys His Phe Cys Thr Arg Leu Ser Gly Tyr Ile Glu Arg 
                245                 250                 255     


Pro Gln Leu Ile Arg Ala Lys Val Pro Ile Val Lys Phe Arg Asp Lys 
            260                 265                 270         


Val Ser Cys Val Glu Phe Asp Leu Asn Val Asn Asn Ile Val Gly Ile 
        275                 280                 285             


Arg Asn Thr Phe Leu Leu Arg Thr Tyr Ala Tyr Leu Glu Asn Arg Val 
    290                 295                 300                 


Arg Pro Leu Val Leu Val Ile Lys Lys Trp Ala Ser His His Gln Ile 
305                 310                 315                 320 


Asn Asp Ala Ser Arg Gly Thr Leu Ser Ser Tyr Ser Leu Val Leu Met 
                325                 330                 335     


Val Leu His Tyr Leu Gln Thr Leu Pro Glu Pro Ile Leu Pro Ser Leu 
            340                 345                 350         


Gln Lys Ile Tyr Pro Glu Ser Phe Ser Pro Ala Ile Gln Leu His Leu 
        355                 360                 365             


Val His Gln Ala Pro Cys Asn Val Pro Pro Tyr Leu Ser Lys Asn Glu 
    370                 375                 380                 


Ser Asn Leu Gly Asp Leu Leu Leu Gly Phe Leu Lys Tyr Tyr Ala Thr 
385                 390                 395                 400 


Glu Phe Asp Trp Asn Ser Gln Met Ile Ser Val Arg Glu Ala Lys Ala 
                405                 410                 415     


Ile Pro Arg Pro Asp Gly Ile Glu Trp Arg Asn Lys Tyr Ile Cys Val 
            420                 425                 430         


Glu Glu Pro Phe Asp Gly Thr Asn Thr Ala Arg Ala Val His Glu Lys 
        435                 440                 445             


Gln Lys Phe Asp Met Ile Lys Asp Gln Phe Leu Lys Ser Trp His Arg 
    450                 455                 460                 


Leu Lys Asn Lys Arg Asp Leu Asn Ser Ile Leu Pro Val Arg Ala Ala 
465                 470                 475                 480 


Val Leu Lys Arg 
                


<210>  3537
<211>  905
<212>  PRT
<213>  homo sapiens

<400>  3537

Met Ser Ser Glu Cys Asp Gly Gly Ser Lys Ala Val Met Asn Gly Leu 
1               5                   10                  15      


Ala Pro Gly Ser Asn Gly Gln Asp Lys Ala Thr Ala Asp Pro Leu Arg 
            20                  25                  30          


Ala Arg Ser Ile Ser Ala Val Lys Ile Ile Pro Val Lys Thr Val Lys 
        35                  40                  45              


Asn Ala Ser Gly Leu Val Leu Pro Thr Asp Met Asp Pro Thr Lys Ile 
    50                  55                  60                  


Cys Thr Gly Lys Gly Ala Val Thr Leu Arg Ala Ser Ser Ser Tyr Arg 
65                  70                  75                  80  


Glu Thr Pro Ser Ser Ser Pro Ala Ser Pro Gln Glu Thr Arg Gln His 
                85                  90                  95      


Glu Ser Lys Pro Gly Leu Glu Pro Glu Pro Ser Ser Ala Asp Glu Trp 
            100                 105                 110         


Arg Leu Ser Ser Ser Ala Asp Ala Asn Gly Asn Ala Gln Pro Ser Ser 
        115                 120                 125             


Leu Ala Ala Lys Gly Tyr Arg Ser Val His Pro Asn Leu Pro Ser Asp 
    130                 135                 140                 


Lys Ser Gln Arg Trp Pro His His Ser Gln Pro Ala Arg Ala Ser Gly 
145                 150                 155                 160 


Ser Phe Ala Pro Ile Ser Gln Thr Pro Pro Ser Phe Ser Pro Pro Pro 
                165                 170                 175     


Pro Leu Val Pro Pro Ala Pro Glu Asp Leu Arg Arg Val Ser Glu Pro 
            180                 185                 190         


Asp Leu Thr Gly Ala Val Ser Ser Thr Asp Ser Ser Pro Leu Leu Asn 
        195                 200                 205             


Glu Val Ser Ser Ser Leu Ile Gly Thr Asp Ser Gln Ala Phe Pro Ser 
    210                 215                 220                 


Val Ser Lys Pro Ser Ser Ala Tyr Pro Ser Thr Thr Ile Val Asn Pro 
225                 230                 235                 240 


Thr Ile Val Leu Leu Gln His Asn Arg Glu Gln Gln Lys Arg Leu Ser 
                245                 250                 255     


Ser Leu Ser Asp Pro Val Ser Glu Arg Arg Val Gly Glu Gln Asp Ser 
            260                 265                 270         


Ala Pro Thr Gln Glu Lys Pro Thr Ser Pro Gly Lys Ala Ile Glu Lys 
        275                 280                 285             


Arg Ala Lys Asp Asp Ser Arg Arg Val Val Lys Ser Thr Gln Asp Leu 
    290                 295                 300                 


Ser Asp Val Ser Met Asp Glu Val Gly Ile Pro Leu Arg Asn Thr Glu 
305                 310                 315                 320 


Arg Ser Lys Asp Trp Tyr Lys Thr Met Phe Lys Gln Ile His Lys Leu 
                325                 330                 335     


Asn Arg Asp Asp Asp Ser Asp Leu Tyr Ser Pro Arg Tyr Ser Phe Ser 
            340                 345                 350         


Glu Asp Thr Lys Ser Pro Leu Ser Val Pro Arg Ser Lys Ser Glu Met 
        355                 360                 365             


Ser Tyr Ile Asp Gly Glu Lys Val Val Lys Arg Ser Ala Thr Leu Pro 
    370                 375                 380                 


Leu Pro Ala Arg Ser Ser Ser Leu Lys Ser Ser Ser Glu Arg Asn Asp 
385                 390                 395                 400 


Trp Glu Pro Pro Asp Lys Lys Val Asp Thr Arg Lys Tyr Arg Ala Glu 
                405                 410                 415     


Pro Lys Ser Ile Tyr Glu Tyr Gln Pro Gly Lys Ser Ser Val Leu Thr 
            420                 425                 430         


Asn Glu Lys Met Ser Arg Asp Ile Ser Pro Glu Glu Ile Asp Leu Lys 
        435                 440                 445             


Asn Glu Pro Trp Tyr Lys Phe Phe Ser Glu Leu Glu Phe Gly Lys Pro 
    450                 455                 460                 


Pro Pro Lys Lys Ile Trp Asp Tyr Thr Pro Gly Asp Cys Ser Ile Leu 
465                 470                 475                 480 


Pro Arg Glu Asp Arg Lys Ser Ser Ala Ile Ser Pro Thr Pro Glu Ile 
                485                 490                 495     


Ser Ser Glu Thr Pro Gly Tyr Ile Tyr Ser Ser Asn Phe His Ala Val 
            500                 505                 510         


Lys Arg Glu Ser Asp Gly Ala Pro Gly Asp Leu Thr Ser Leu Glu Asn 
        515                 520                 525             


Glu Arg Gln Ile Tyr Lys Ser Val Leu Glu Gly Gly Asp Ile Pro Leu 
    530                 535                 540                 


Gln Gly Leu Ser Gly Leu Lys Arg Pro Ser Ser Ser Ala Ser Thr Lys 
545                 550                 555                 560 


Asp Ser Glu Ser Pro Arg His Phe Ile Pro Ala Asp Tyr Leu Glu Ser 
                565                 570                 575     


Thr Glu Glu Phe Ile Arg Arg Arg His Asp Asp Lys Glu Lys Leu Leu 
            580                 585                 590         


Ala Asp Gln Arg Arg Leu Lys Arg Glu Gln Glu Glu Ala Asp Ile Ala 
        595                 600                 605             


Ala Arg Arg His Thr Gly Val Ile Pro Thr His His Gln Phe Ile Thr 
    610                 615                 620                 


Asn Glu Arg Phe Gly Asp Leu Leu Asn Ile Asp Asp Thr Ala Lys Arg 
625                 630                 635                 640 


Lys Ser Gly Ser Glu Met Arg Pro Ala Arg Ala Lys Phe Asp Phe Lys 
                645                 650                 655     


Ala Gln Thr Leu Lys Glu Leu Pro Leu Gln Lys Gly Asp Ile Val Tyr 
            660                 665                 670         


Ile Tyr Lys Gln Ile Asp Gln Asn Trp Tyr Glu Gly Glu His His Gly 
        675                 680                 685             


Arg Val Gly Ile Phe Pro Arg Thr Tyr Ile Glu Leu Leu Pro Pro Ala 
    690                 695                 700                 


Glu Lys Ala Gln Pro Lys Lys Leu Thr Pro Val Gln Val Leu Glu Tyr 
705                 710                 715                 720 


Gly Glu Ala Ile Ala Lys Phe Asn Phe Asn Gly Asp Thr Gln Val Glu 
                725                 730                 735     


Met Ser Phe Arg Lys Gly Glu Arg Ile Thr Leu Leu Arg Gln Val Asp 
            740                 745                 750         


Glu Asn Trp Tyr Glu Gly Arg Ile Pro Gly Thr Ser Arg Gln Gly Ile 
        755                 760                 765             


Phe Pro Ile Thr Tyr Val Asp Val Ile Lys Arg Pro Leu Val Lys Asn 
    770                 775                 780                 


Pro Val Asp Tyr Met Asp Leu Pro Phe Ser Ser Ser Pro Ser Arg Ser 
785                 790                 795                 800 


Ala Thr Ala Ser Pro Gln Leu Ser His His Ser Leu Arg Ala Gly Pro 
                805                 810                 815     


Asp Leu Thr Glu Ser Glu Lys Ser Tyr Val Gln Pro Gln Ala Gln Gln 
            820                 825                 830         


Arg Arg Val Thr Pro Asp Arg Ser Gln Thr Ser Gln Asp Leu Phe Ser 
        835                 840                 845             


Tyr Gln Ala Leu Tyr Ser Tyr Ile Pro Gln Asn Asp Asp Glu Leu Glu 
    850                 855                 860                 


Leu Arg Asp Gly Asp Ile Val Asp Val Met Glu Lys Cys Asp Asp Gly 
865                 870                 875                 880 


Trp Phe Val Gly Thr Ser Arg Arg Thr Lys Gln Phe Gly Thr Phe Pro 
                885                 890                 895     


Gly Asn Tyr Val Lys Pro Leu Tyr Leu 
            900                 905 


<210>  3538
<211>  322
<212>  PRT
<213>  homo sapiens

<400>  3538

Met Pro Val Thr Val Thr Arg Thr Thr Ile Thr Thr Thr Thr Thr Ser 
1               5                   10                  15      


Ser Ser Gly Leu Gly Ser Pro Met Ile Val Gly Ser Pro Arg Ala Leu 
            20                  25                  30          


Thr Gln Pro Leu Gly Leu Leu Arg Leu Leu Gln Leu Val Ser Thr Cys 
        35                  40                  45              


Val Ala Phe Ser Leu Val Ala Ser Val Gly Ala Trp Thr Gly Ser Met 
    50                  55                  60                  


Gly Asn Trp Ser Met Phe Thr Trp Cys Phe Cys Phe Ser Val Thr Leu 
65                  70                  75                  80  


Ile Ile Leu Ile Val Glu Leu Cys Gly Leu Gln Ala Arg Phe Pro Leu 
                85                  90                  95      


Ser Trp Arg Asn Phe Pro Ile Thr Phe Ala Cys Tyr Ala Ala Leu Phe 
            100                 105                 110         


Cys Leu Ser Ala Ser Ile Ile Tyr Pro Thr Thr Tyr Val Gln Phe Leu 
        115                 120                 125             


Ser His Gly Arg Ser Arg Asp His Ala Ile Ala Ala Thr Phe Phe Ser 
    130                 135                 140                 


Cys Ile Ala Cys Val Ala Tyr Ala Thr Glu Val Ala Trp Thr Arg Ala 
145                 150                 155                 160 


Arg Pro Gly Glu Ile Thr Gly Tyr Met Ala Thr Val Pro Gly Leu Leu 
                165                 170                 175     


Lys Val Leu Glu Thr Phe Val Ala Cys Ile Ile Phe Ala Phe Ile Ser 
            180                 185                 190         


Asp Pro Asn Leu Tyr Gln His Gln Pro Ala Leu Glu Trp Cys Val Ala 
        195                 200                 205             


Val Tyr Ala Ile Cys Phe Ile Leu Ala Ala Ile Ala Ile Leu Leu Asn 
    210                 215                 220                 


Leu Gly Glu Cys Thr Asn Val Leu Pro Ile Pro Phe Pro Ser Phe Leu 
225                 230                 235                 240 


Ser Gly Leu Ala Leu Leu Ser Val Leu Leu Tyr Ala Thr Ala Leu Val 
                245                 250                 255     


Leu Trp Pro Leu Tyr Gln Phe Asp Glu Lys Tyr Gly Gly Gln Pro Arg 
            260                 265                 270         


Arg Ser Arg Asp Val Ser Cys Ser Arg Ser His Ala Tyr Tyr Val Cys 
        275                 280                 285             


Ala Trp Asp Arg Arg Leu Ala Val Ala Ile Leu Thr Ala Ile Asn Leu 
    290                 295                 300                 


Leu Ala Tyr Val Ala Asp Leu Val His Ser Ala His Leu Val Phe Val 
305                 310                 315                 320 


Lys Val 
        


<210>  3539
<211>  605
<212>  PRT
<213>  homo sapiens

<400>  3539

Met Gln Cys Cys Gly Leu Val His Arg Arg Arg Val Arg Val Ser Tyr 
1               5                   10                  15      


Gly Ser Ala Asp Ser Tyr Thr Ser Arg Pro Ser Asp Ser Asp Val Ser 
            20                  25                  30          


Leu Glu Glu Asp Arg Glu Ala Val Arg Arg Glu Ala Glu Arg Gln Ala 
        35                  40                  45              


Gln Ala Gln Leu Glu Lys Ala Lys Thr Lys Pro Val Ala Phe Ala Val 
    50                  55                  60                  


Arg Thr Asn Val Ser Tyr Ser Ala Ala His Glu Asp Asp Val Pro Val 
65                  70                  75                  80  


Pro Gly Met Ala Ile Ser Phe Glu Ala Lys Asp Phe Leu His Val Lys 
                85                  90                  95      


Glu Lys Phe Asn Asn Asp Trp Trp Ile Gly Arg Leu Val Lys Glu Gly 
            100                 105                 110         


Cys Glu Ile Gly Phe Ile Pro Ser Pro Val Lys Leu Glu Asn Met Arg 
        115                 120                 125             


Leu Gln His Glu Gln Arg Ala Lys Gln Gly Lys Phe Tyr Ser Ser Lys 
    130                 135                 140                 


Ser Gly Gly Asn Ser Ser Ser Ser Leu Gly Asp Ile Val Pro Ser Ser 
145                 150                 155                 160 


Arg Lys Ser Thr Pro Pro Ser Ser Ala Ile Asp Ile Asp Ala Thr Gly 
                165                 170                 175     


Leu Asp Ala Glu Glu Asn Asp Ile Pro Ala Asn His Arg Ser Pro Lys 
            180                 185                 190         


Pro Ser Ala Asn Ser Val Thr Ser Pro His Ser Lys Glu Lys Arg Met 
        195                 200                 205             


Pro Phe Phe Lys Lys Thr Glu His Thr Pro Pro Tyr Asp Val Val Pro 
    210                 215                 220                 


Ser Met Arg Pro Val Val Leu Val Gly Pro Ser Leu Lys Gly Tyr Glu 
225                 230                 235                 240 


Val Thr Asp Met Met Gln Lys Ala Leu Phe Asp Phe Leu Lys His Arg 
                245                 250                 255     


Phe Glu Gly Arg Ile Ser Ile Thr Arg Val Thr Ala Asp Ile Ser Leu 
            260                 265                 270         


Ala Lys Arg Ser Val Leu Asn Asn Pro Ser Lys His Ala Ile Ile Glu 
        275                 280                 285             


Arg Ser Asn Thr Arg Ser Ser Leu Ala Glu Val Gln Ser Glu Ile Glu 
    290                 295                 300                 


Arg Ile Phe Glu Leu Ala Arg Thr Leu Gln Leu Val Val Leu Asp Ala 
305                 310                 315                 320 


Asp Thr Ile Asn His Pro Ala Gln Leu Ser Lys Thr Ser Leu Ala Pro 
                325                 330                 335     


Ile Ile Val Tyr Val Lys Ile Ser Ser Pro Lys Val Leu Gln Arg Leu 
            340                 345                 350         


Ile Lys Ser Arg Gly Lys Ser Gln Ala Lys His Leu Asn Val Gln Met 
        355                 360                 365             


Val Ala Ala Asp Lys Leu Ala Gln Cys Pro Pro Glu Leu Phe Asp Val 
    370                 375                 380                 


Ile Leu Asp Glu Asn Gln Leu Glu Asp Ala Cys Glu His Leu Ala Asp 
385                 390                 395                 400 


Tyr Leu Glu Ala Tyr Trp Lys Ala Thr His Pro Pro Ser Ser Ser Leu 
                405                 410                 415     


Pro Asn Pro Leu Leu Ser Arg Thr Leu Ala Thr Ser Ser Leu Pro Leu 
            420                 425                 430         


Ser Pro Thr Leu Ala Ser Asn Ser Gln Gly Ser Gln Gly Asp Gln Arg 
        435                 440                 445             


Thr Asp Arg Ser Ala Pro Ile Arg Ser Ala Ser Gln Ala Glu Glu Glu 
    450                 455                 460                 


Pro Ser Val Glu Pro Val Lys Lys Ser Gln His Arg Ser Ser Ser Ser 
465                 470                 475                 480 


Ala Pro His His Asn His Arg Ser Gly Thr Ser Arg Gly Leu Ser Arg 
                485                 490                 495     


Gln Glu Thr Phe Asp Ser Glu Thr Gln Glu Ser Arg Asp Ser Ala Tyr 
            500                 505                 510         


Val Glu Pro Lys Glu Asp Tyr Ser His Asp His Val Asp His Tyr Ala 
        515                 520                 525             


Ser His Arg Asp His Asn His Arg Asp Glu Thr His Gly Ser Ser Asp 
    530                 535                 540                 


His Arg His Arg Glu Ser Arg His Arg Ser Arg Asp Val Asp Arg Glu 
545                 550                 555                 560 


Gln Asp His Asn Glu Cys Asn Lys Gln Arg Ser Arg His Lys Ser Lys 
                565                 570                 575     


Asp Arg Tyr Cys Glu Lys Asp Gly Glu Val Ile Ser Lys Lys Arg Asn 
            580                 585                 590         


Glu Ala Gly Glu Trp Asn Arg Asp Val Tyr Ile Arg Gln 
        595                 600                 605 


<210>  3540
<211>  146
<212>  PRT
<213>  homo sapiens

<400>  3540

Met Asn Ser Lys Gly Gln Tyr Pro Thr Gln Pro Thr Tyr Pro Val Gln 
1               5                   10                  15      


Pro Pro Gly Asn Pro Val Tyr Pro Gln Thr Leu His Leu Pro Gln Ala 
            20                  25                  30          


Pro Pro Tyr Thr Asp Ala Pro Pro Ala Tyr Ser Glu Leu Tyr Arg Pro 
        35                  40                  45              


Ser Phe Val His Pro Gly Ala Ala Thr Val Pro Thr Met Ser Ala Ala 
    50                  55                  60                  


Ile Pro Met Ala Tyr Tyr Pro Val Gly Pro Ile Tyr Pro Pro Gly Ser 
65                  70                  75                  80  


Thr Val Leu Val Glu Gly Gly Tyr Asp Ala Gly Ala Arg Phe Gly Ala 
                85                  90                  95      


Gly Ala Thr Ala Gly Asn Ile Pro Pro Pro Pro Pro Gly Cys Pro Pro 
            100                 105                 110         


Asn Ala Ala Gln Leu Ala Val Met Gln Gly Ala Asn Val Leu Val Thr 
        115                 120                 125             


Gln Arg Lys Gly Asn Phe Phe Met Gly Gly Ser Asp Gly Gly Tyr Thr 
    130                 135                 140                 


Ile Trp 
145     


<210>  3541
<211>  304
<212>  PRT
<213>  homo sapiens

<400>  3541

Met Phe Ser Val Leu Ser Tyr Gly Arg Leu Val Ala Arg Ala Val Leu 
1               5                   10                  15      


Gly Gly Leu Ser Gln Thr Asp Pro Arg Ala Gly Gly Gly Gly Gly Gly 
            20                  25                  30          


Asp Tyr Gly Leu Val Thr Ala Gly Cys Gly Phe Gly Lys Asp Phe Arg 
        35                  40                  45              


Lys Gly Leu Leu Lys Lys Gly Ala Cys Tyr Gly Asp Asp Ala Cys Phe 
    50                  55                  60                  


Val Ala Arg His Arg Ser Ala Asp Val Leu Gly Val Ala Asp Gly Val 
65                  70                  75                  80  


Gly Gly Trp Arg Asp Tyr Gly Val Asp Pro Ser Gln Phe Ser Gly Thr 
                85                  90                  95      


Leu Met Arg Thr Cys Glu Arg Leu Val Lys Glu Gly Arg Phe Val Pro 
            100                 105                 110         


Ser Asn Pro Ile Gly Ile Leu Thr Thr Ser Tyr Cys Glu Leu Leu Gln 
        115                 120                 125             


Asn Lys Val Pro Leu Leu Gly Ser Ser Thr Ala Cys Ile Val Val Leu 
    130                 135                 140                 


Asp Arg Thr Ser His Arg Leu His Thr Ala Asn Leu Gly Asp Ser Gly 
145                 150                 155                 160 


Phe Leu Val Val Arg Gly Gly Glu Val Val His Arg Ser Asp Glu Gln 
                165                 170                 175     


Gln His Tyr Phe Asn Thr Pro Phe Gln Leu Ser Ile Ala Pro Pro Glu 
            180                 185                 190         


Ala Glu Gly Val Val Leu Ser Asp Ser Pro Asp Ala Ala Asp Ser Thr 
        195                 200                 205             


Ser Phe Asp Val Gln Leu Gly Asp Ile Ile Leu Thr Ala Thr Asp Gly 
    210                 215                 220                 


Leu Phe Asp Asn Met Pro Asp Tyr Met Ile Leu Gln Glu Leu Lys Lys 
225                 230                 235                 240 


Leu Lys Asn Ser Asn Tyr Glu Ser Ile Gln Gln Thr Ala Arg Ser Ile 
                245                 250                 255     


Ala Glu Gln Ala His Glu Leu Ala Tyr Asp Pro Asn Tyr Met Ser Pro 
            260                 265                 270         


Phe Ala Gln Phe Ala Cys Asp Asn Gly Leu Asn Val Arg Gly Gly Lys 
        275                 280                 285             


Pro Asp Asp Ile Thr Val Leu Leu Ser Ile Val Ala Glu Tyr Thr Asp 
    290                 295                 300                 


<210>  3542
<211>  763
<212>  PRT
<213>  homo sapiens

<400>  3542

Met Lys Thr Ser Pro Arg Arg Pro Leu Ile Leu Lys Arg Arg Arg Leu 
1               5                   10                  15      


Pro Leu Pro Val Gln Asn Ala Pro Ser Glu Thr Ser Glu Glu Glu Pro 
            20                  25                  30          


Lys Arg Ser Pro Ala Gln Gln Glu Ser Asn Gln Ala Glu Ala Ser Lys 
        35                  40                  45              


Glu Val Ala Glu Ser Asn Ser Cys Lys Phe Pro Ala Gly Ile Lys Ile 
    50                  55                  60                  


Ile Asn His Pro Thr Met Pro Asn Thr Gln Val Val Ala Ile Pro Asn 
65                  70                  75                  80  


Asn Ala Asn Ile His Ser Ile Ile Thr Ala Leu Thr Ala Lys Gly Lys 
                85                  90                  95      


Glu Ser Gly Ser Ser Gly Pro Asn Lys Phe Ile Leu Ile Ser Cys Gly 
            100                 105                 110         


Gly Ala Pro Thr Gln Pro Pro Gly Leu Arg Pro Gln Thr Gln Thr Ser 
        115                 120                 125             


Tyr Asp Ala Lys Arg Thr Glu Val Thr Leu Glu Thr Leu Gly Pro Lys 
    130                 135                 140                 


Pro Ala Ala Arg Asp Val Asn Leu Pro Arg Pro Pro Gly Ala Leu Cys 
145                 150                 155                 160 


Glu Gln Lys Arg Glu Thr Cys Ala Asp Gly Glu Ala Ala Gly Cys Thr 
                165                 170                 175     


Ile Asn Asn Ser Leu Ser Asn Ile Gln Trp Leu Arg Lys Met Ser Ser 
            180                 185                 190         


Asp Gly Leu Gly Ser Arg Ser Ile Lys Gln Glu Met Glu Glu Lys Glu 
        195                 200                 205             


Asn Cys His Leu Glu Gln Arg Gln Val Lys Val Glu Glu Pro Ser Arg 
    210                 215                 220                 


Pro Ser Ala Ser Trp Gln Asn Ser Val Ser Glu Arg Pro Pro Tyr Ser 
225                 230                 235                 240 


Tyr Met Ala Met Ile Gln Phe Ala Ile Asn Ser Thr Glu Arg Lys Arg 
                245                 250                 255     


Met Thr Leu Lys Asp Ile Tyr Thr Trp Ile Glu Asp His Phe Pro Tyr 
            260                 265                 270         


Phe Lys His Ile Ala Lys Pro Gly Trp Lys Asn Ser Ile Arg His Asn 
        275                 280                 285             


Leu Ser Leu His Asp Met Phe Val Arg Glu Thr Ser Ala Asn Gly Lys 
    290                 295                 300                 


Val Ser Phe Trp Thr Ile His Pro Ser Ala Asn Arg Tyr Leu Thr Leu 
305                 310                 315                 320 


Asp Gln Val Phe Lys Pro Leu Asp Pro Gly Ser Pro Gln Leu Pro Glu 
                325                 330                 335     


His Leu Glu Ser Gln Gln Lys Arg Pro Asn Pro Glu Leu Arg Arg Asn 
            340                 345                 350         


Met Thr Ile Lys Thr Glu Leu Pro Leu Gly Ala Arg Arg Lys Met Lys 
        355                 360                 365             


Pro Leu Leu Pro Arg Val Ser Ser Tyr Leu Val Pro Ile Gln Phe Pro 
    370                 375                 380                 


Val Asn Gln Ser Leu Val Leu Gln Pro Ser Val Lys Val Pro Leu Pro 
385                 390                 395                 400 


Leu Ala Ala Ser Leu Met Ser Ser Glu Leu Ala Arg His Ser Lys Arg 
                405                 410                 415     


Val Arg Ile Ala Pro Lys Val Leu Leu Ala Glu Glu Gly Ile Ala Pro 
            420                 425                 430         


Leu Ser Ser Ala Gly Pro Gly Lys Glu Glu Lys Leu Leu Phe Gly Glu 
        435                 440                 445             


Gly Phe Ser Pro Leu Leu Pro Val Gln Thr Ile Lys Glu Glu Glu Ile 
    450                 455                 460                 


Gln Pro Gly Glu Glu Met Pro His Leu Ala Arg Pro Ile Lys Val Glu 
465                 470                 475                 480 


Ser Pro Pro Leu Glu Glu Trp Pro Ser Pro Ala Pro Ser Phe Lys Glu 
                485                 490                 495     


Glu Ser Ser His Ser Trp Glu Asp Ser Ser Gln Ser Pro Thr Pro Arg 
            500                 505                 510         


Pro Lys Lys Ser Tyr Ser Gly Leu Arg Ser Pro Thr Arg Cys Val Ser 
        515                 520                 525             


Glu Met Leu Val Ile Gln His Arg Glu Arg Arg Glu Arg Ser Arg Ser 
    530                 535                 540                 


Arg Arg Lys Gln His Leu Leu Pro Pro Cys Val Asp Glu Pro Glu Leu 
545                 550                 555                 560 


Leu Phe Ser Glu Gly Pro Ser Thr Ser Arg Trp Ala Ala Glu Leu Pro 
                565                 570                 575     


Phe Pro Ala Asp Ser Ser Asp Pro Ala Ser Gln Leu Ser Tyr Ser Gln 
            580                 585                 590         


Glu Val Gly Gly Pro Phe Lys Thr Pro Ile Lys Glu Thr Leu Pro Ile 
        595                 600                 605             


Ser Ser Thr Pro Ser Lys Ser Val Leu Pro Arg Thr Pro Glu Ser Trp 
    610                 615                 620                 


Arg Leu Thr Pro Pro Ala Lys Val Gly Gly Leu Asp Phe Ser Pro Val 
625                 630                 635                 640 


Gln Thr Ser Gln Gly Ala Ser Asp Pro Leu Pro Asp Pro Leu Gly Leu 
                645                 650                 655     


Met Asp Leu Ser Thr Thr Pro Leu Gln Ser Ala Pro Pro Leu Glu Ser 
            660                 665                 670         


Pro Gln Arg Leu Leu Ser Ser Glu Pro Leu Asp Leu Ile Ser Val Pro 
        675                 680                 685             


Phe Gly Asn Ser Ser Pro Ser Asp Ile Asp Val Pro Lys Pro Gly Ser 
    690                 695                 700                 


Pro Glu Pro Gln Val Ser Gly Leu Ala Ala Asn Arg Ser Leu Thr Glu 
705                 710                 715                 720 


Gly Leu Val Leu Asp Thr Met Asn Asp Ser Leu Ser Lys Ile Leu Leu 
                725                 730                 735     


Asp Ile Ser Phe Pro Gly Leu Asp Glu Asp Pro Leu Gly Pro Asp Asn 
            740                 745                 750         


Ile Asn Trp Ser Gln Phe Ile Pro Glu Leu Gln 
        755                 760             


<210>  3543
<211>  601
<212>  PRT
<213>  homo sapiens

<400>  3543

Met His Cys Lys Val Ser Leu Leu Asp Asp Thr Val Tyr Glu Cys Val 
1               5                   10                  15      


Val Glu Lys His Ala Lys Gly Gln Asp Leu Leu Lys Arg Val Cys Glu 
            20                  25                  30          


His Leu Asn Leu Leu Glu Glu Asp Tyr Phe Gly Leu Ala Ile Trp Asp 
        35                  40                  45              


Asn Ala Thr Ser Lys Thr Trp Leu Asp Ser Ala Lys Glu Ile Lys Lys 
    50                  55                  60                  


Gln Val Arg Gly Val Pro Trp Asn Phe Thr Phe Asn Val Lys Phe Tyr 
65                  70                  75                  80  


Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr Leu 
                85                  90                  95      


Cys Leu Gln Leu Arg Gln Asp Ile Val Ala Gly Arg Leu Pro Cys Ser 
            100                 105                 110         


Phe Ala Thr Leu Ala Leu Leu Gly Ser Tyr Thr Ile Gln Ser Glu Leu 
        115                 120                 125             


Gly Asp Tyr Asp Pro Glu Leu His Gly Val Asp Tyr Val Ser Asp Phe 
    130                 135                 140                 


Lys Leu Ala Pro Asn Gln Thr Lys Glu Leu Glu Glu Lys Val Met Glu 
145                 150                 155                 160 


Leu His Lys Ser Tyr Arg Ser Met Thr Pro Ala Gln Ala Asp Leu Glu 
                165                 170                 175     


Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His 
            180                 185                 190         


Lys Ala Lys Asp Leu Glu Gly Val Asp Ile Ile Leu Gly Val Cys Ser 
        195                 200                 205             


Ser Gly Leu Leu Val Tyr Lys Asp Lys Leu Arg Ile Asn Arg Phe Pro 
    210                 215                 220                 


Trp Pro Lys Val Leu Lys Ile Ser Tyr Lys Arg Ser Ser Phe Phe Ile 
225                 230                 235                 240 


Lys Ile Arg Pro Gly Glu Gln Glu Gln Tyr Glu Ser Thr Ile Gly Phe 
                245                 250                 255     


Lys Leu Pro Ser Tyr Arg Ala Ala Lys Lys Leu Trp Lys Val Cys Val 
            260                 265                 270         


Glu His His Thr Phe Phe Arg Leu Thr Ser Thr Asp Thr Ile Pro Lys 
        275                 280                 285             


Ser Lys Phe Leu Ala Leu Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr 
    290                 295                 300                 


Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro 
305                 310                 315                 320 


His Phe Glu Arg Thr Ala Ser Lys Arg Ala Ser Arg Ser Leu Asp Gly 
                325                 330                 335     


Ala Ala Ala Val Asp Ser Ala Asp Arg Ser Pro Arg Pro Thr Ser Ala 
            340                 345                 350         


Pro Ala Ile Thr Gln Gly Gln Val Ala Glu Gly Gly Val Leu Asp Ala 
        355                 360                 365             


Ser Ala Lys Lys Thr Val Val Pro Lys Ala Gln Lys Glu Thr Val Lys 
    370                 375                 380                 


Ala Glu Val Lys Lys Glu Asp Glu Pro Pro Glu Gln Ala Glu Pro Glu 
385                 390                 395                 400 


Pro Thr Glu Ala Trp Lys Asp Leu Asp Lys Ser Gln Glu Glu Ile Lys 
                405                 410                 415     


Lys His His Ala Ser Ile Ser Glu Leu Lys Lys Asn Phe Met Glu Ser 
            420                 425                 430         


Val Pro Glu Pro Arg Pro Ser Glu Trp Asp Lys Arg Leu Ser Thr His 
        435                 440                 445             


Ser Pro Phe Arg Thr Leu Asn Ile Asn Gly Gln Ile Pro Thr Gly Glu 
    450                 455                 460                 


Gly Pro Pro Leu Val Lys Thr Gln Thr Val Thr Ile Ser Asp Asn Ala 
465                 470                 475                 480 


Asn Ala Val Lys Ser Glu Ile Pro Thr Lys Asp Val Pro Ile Val His 
                485                 490                 495     


Thr Glu Thr Lys Thr Ile Thr Tyr Glu Ala Ala Gln Thr Asp Asp Asn 
            500                 505                 510         


Ser Gly Asp Leu Asp Pro Gly Val Leu Leu Thr Ala Gln Thr Ile Thr 
        515                 520                 525             


Ser Glu Thr Pro Ser Ser Thr Thr Thr Thr Gln Ile Thr Lys Thr Val 
    530                 535                 540                 


Lys Gly Gly Ile Ser Glu Thr Arg Ile Glu Lys Arg Ile Val Ile Thr 
545                 550                 555                 560 


Gly Asp Ala Asp Ile Asp His Asp Gln Val Leu Val Gln Ala Ile Lys 
                565                 570                 575     


Glu Ala Lys Glu Gln His Pro Asp Met Ser Val Thr Lys Val Val Val 
            580                 585                 590         


His Gln Glu Thr Glu Ile Ala Asp Glu 
        595                 600     


<210>  3544
<211>  622
<212>  PRT
<213>  homo sapiens

<400>  3544

Met Ala Glu Asn Thr Glu Gly Asp Leu Asn Ser Asn Leu Leu His Ala 
1               5                   10                  15      


Pro Tyr His Thr Gly Asp Pro Gln Leu Asp Thr Ala Ile Gly Gln Trp 
            20                  25                  30          


Leu Arg Trp Asp Lys Asn Pro Lys Thr Lys Glu Gln Ile Glu Asn Leu 
        35                  40                  45              


Leu Arg Asn Gly Met Asn Lys Glu Leu Arg Asp Arg Leu Cys Cys Arg 
    50                  55                  60                  


Met Thr Phe Gly Thr Ala Gly Leu Arg Ser Ala Met Gly Ala Gly Phe 
65                  70                  75                  80  


Cys Tyr Ile Asn Asp Leu Thr Val Ile Gln Ser Thr Gln Gly Met Tyr 
                85                  90                  95      


Lys Tyr Leu Glu Arg Cys Phe Ser Asp Phe Lys Gln Arg Gly Phe Val 
            100                 105                 110         


Val Gly Tyr Asp Thr Arg Gly Gln Val Thr Ser Ser Cys Ser Ser Gln 
        115                 120                 125             


Arg Leu Ala Lys Leu Thr Ala Ala Val Leu Leu Ala Lys Asp Val Pro 
    130                 135                 140                 


Val Tyr Leu Phe Ser Arg Tyr Val Pro Thr Pro Phe Val Pro Tyr Ala 
145                 150                 155                 160 


Val Gln Lys Leu Lys Ala Val Ala Gly Val Met Ile Thr Ala Ser His 
                165                 170                 175     


Asn Arg Lys Glu Asp Asn Gly Tyr Lys Val Tyr Trp Glu Thr Gly Ala 
            180                 185                 190         


Gln Ile Thr Ser Pro His Asp Lys Glu Ile Leu Lys Cys Ile Glu Glu 
        195                 200                 205             


Cys Val Glu Pro Trp Asn Gly Ser Trp Asn Asp Asn Leu Val Asp Thr 
    210                 215                 220                 


Ser Pro Leu Lys Arg Asp Pro Leu Gln Asp Ile Cys Arg Arg Tyr Met 
225                 230                 235                 240 


Glu Asp Leu Lys Lys Ile Cys Phe Tyr Arg Glu Leu Asn Ser Lys Thr 
                245                 250                 255     


Thr Leu Lys Phe Val His Thr Ser Phe His Gly Val Gly His Asp Tyr 
            260                 265                 270         


Val Gln Leu Ala Phe Lys Val Phe Gly Phe Lys Pro Pro Ile Pro Val 
        275                 280                 285             


Pro Glu Gln Lys Asp Pro Asp Pro Asp Phe Ser Thr Val Lys Cys Pro 
    290                 295                 300                 


Asn Pro Glu Glu Gly Glu Ser Val Leu Glu Leu Ser Leu Arg Leu Ala 
305                 310                 315                 320 


Glu Lys Glu Asn Ala Arg Val Val Leu Ala Thr Asp Pro Asp Ala Asp 
                325                 330                 335     


Arg Leu Ala Ala Ala Glu Leu Gln Glu Asn Gly Cys Trp Lys Val Phe 
            340                 345                 350         


Thr Gly Asn Glu Leu Ala Ala Leu Phe Gly Trp Trp Met Phe Asp Cys 
        355                 360                 365             


Trp Lys Lys Asn Lys Ser Arg Asn Ala Asp Val Lys Asn Val Tyr Met 
    370                 375                 380                 


Leu Ala Thr Thr Val Ser Ser Lys Ile Leu Lys Ala Ile Ala Leu Lys 
385                 390                 395                 400 


Glu Gly Phe His Phe Glu Glu Thr Leu Pro Gly Phe Lys Trp Ile Gly 
                405                 410                 415     


Ser Arg Ile Ile Asp Leu Leu Glu Asn Gly Lys Glu Val Leu Phe Ala 
            420                 425                 430         


Phe Glu Glu Ser Ile Gly Phe Leu Cys Gly Thr Ser Val Leu Asp Lys 
        435                 440                 445             


Asp Gly Val Ser Ala Ala Val Val Val Ala Glu Met Ala Ser Tyr Leu 
    450                 455                 460                 


Glu Thr Met Asn Ile Thr Leu Lys Gln Gln Leu Val Lys Val Tyr Glu 
465                 470                 475                 480 


Lys Tyr Gly Tyr His Ile Ser Lys Thr Ser Tyr Phe Leu Cys Tyr Glu 
                485                 490                 495     


Pro Pro Thr Ile Lys Ser Ile Phe Glu Arg Leu Arg Asn Phe Asp Ser 
            500                 505                 510         


Pro Lys Glu Tyr Pro Lys Phe Cys Gly Thr Phe Ala Ile Leu His Val 
        515                 520                 525             


Arg Asp Val Thr Thr Gly Tyr Asp Ser Ser Gln Pro Asn Lys Lys Ser 
    530                 535                 540                 


Val Leu Pro Val Ser Lys Asn Ser Gln Met Ile Thr Phe Thr Phe Gln 
545                 550                 555                 560 


Asn Gly Cys Val Ala Thr Leu Arg Thr Ser Gly Thr Glu Pro Lys Ile 
                565                 570                 575     


Lys Tyr Tyr Ala Glu Met Cys Ala Ser Pro Asp Gln Ser Asp Thr Ala 
            580                 585                 590         


Leu Leu Glu Glu Glu Leu Lys Lys Leu Ile Asp Ala Leu Ile Glu Asn 
        595                 600                 605             


Phe Leu Gln Pro Ser Lys Asn Gly Leu Ile Trp Arg Ser Val 
    610                 615                 620         


<210>  3545
<211>  645
<212>  PRT
<213>  homo sapiens

<400>  3545

Met Gly Gln Thr Ser Val Ser Thr Leu Ser Pro Gln Pro Gly Ser Val 
1               5                   10                  15      


Asp Gly Leu Asp Lys Ala Ser Ile Ala Asn Ser Asp Gly Pro Thr Ala 
            20                  25                  30          


Gly Ser Gln Thr Pro Pro Phe Lys Arg Lys Gly Lys Leu Ser Thr Ile 
        35                  40                  45              


Gly Lys Ile Phe Lys Pro Trp Lys Trp Arg Lys Lys Lys Thr Ser Asp 
    50                  55                  60                  


Lys Phe Arg Glu Thr Ser Ala Val Leu Glu Arg Lys Ile Ser Thr Arg 
65                  70                  75                  80  


Gln Ser Arg Glu Glu Leu Ile Arg Arg Gly Val Leu Lys Glu Leu Pro 
                85                  90                  95      


Asp Gln Asp Gly Asp Val Thr Val Asn Phe Glu Asn Ser Asn Gly His 
            100                 105                 110         


Met Ile Pro Ile Gly Glu Glu Ser Thr Arg Glu Glu Asn Val Val Lys 
        115                 120                 125             


Ser Glu Glu Gly Asn Gly Ser Val Ser Glu Lys Thr Pro Pro Leu Glu 
    130                 135                 140                 


Glu Gln Ala Glu Asp Lys Lys Glu Asn Thr Glu Asn His Ser Glu Thr 
145                 150                 155                 160 


Pro Ala Ala Pro Ala Leu Pro Pro Ser Ala Pro Pro Lys Pro Arg Pro 
                165                 170                 175     


Lys Pro Lys Pro Lys Lys Ser Pro Val Pro Pro Lys Gly Ala Thr Ala 
            180                 185                 190         


Gly Ala Ser His Lys Gly Asp Glu Val Pro Pro Ile Lys Lys Asn Thr 
        195                 200                 205             


Lys Ala Pro Gly Lys Gln Ala Pro Val Pro Pro Pro Lys Pro Ala Ser 
    210                 215                 220                 


Arg Asn Thr Thr Arg Glu Ala Ala Gly Ser Ser His Ser Lys Lys Thr 
225                 230                 235                 240 


Thr Gly Ser Lys Ala Ser Ala Ser Pro Ser Thr Ser Ser Thr Ser Ser 
                245                 250                 255     


Arg Pro Lys Ala Ser Lys Glu Thr Val Ser Ser Lys Ala Gly Thr Val 
            260                 265                 270         


Gly Thr Thr Lys Gly Lys Arg Lys Thr Asp Lys Gln Pro Ile Thr Ser 
        275                 280                 285             


His Leu Ser Ser Asp Thr Thr Thr Ser Gly Thr Ser Asp Leu Lys Gly 
    290                 295                 300                 


Glu Pro Ala Glu Thr Arg Val Glu Ser Phe Lys Leu Glu Gln Thr Val 
305                 310                 315                 320 


Pro Gly Ala Glu Glu Gln Asn Thr Gly Lys Phe Lys Ser Met Val Pro 
                325                 330                 335     


Pro Pro Pro Val Ala Pro Ala Pro Ser Pro Leu Ala Pro Pro Leu Pro 
            340                 345                 350         


Leu Glu Asp Gln Cys Ile Thr Ala Ser Asp Thr Pro Val Val Leu Val 
        355                 360                 365             


Ser Val Gly Ala Asp Leu Pro Val Ser Ala Leu Asp Pro Ser Gln Leu 
    370                 375                 380                 


Leu Trp Ala Glu Glu Pro Thr Asn Arg Thr Thr Leu Tyr Ser Gly Thr 
385                 390                 395                 400 


Gly Leu Ser Val Asn Arg Glu Asn Ala Lys Cys Phe Thr Thr Lys Glu 
                405                 410                 415     


Glu Leu Gly Lys Thr Val Pro Gln Leu Leu Thr Pro Gly Leu Met Gly 
            420                 425                 430         


Glu Ser Ser Glu Ser Phe Ser Ala Ser Glu Asp Glu Gly His Arg Glu 
        435                 440                 445             


Tyr Gln Ala Asn Asp Ser Asp Ser Asp Gly Pro Ile Leu Tyr Thr Asp 
    450                 455                 460                 


Asp Glu Asp Glu Asp Glu Asp Glu Asp Gly Ser Gly Glu Ser Ala Leu 
465                 470                 475                 480 


Ala Ser Lys Ile Arg Arg Arg Asp Thr Leu Ala Ile Lys Leu Gly Asn 
                485                 490                 495     


Arg Pro Ser Lys Lys Glu Leu Glu Asp Lys Asn Ile Leu Gln Arg Thr 
            500                 505                 510         


Ser Glu Glu Glu Arg Gln Glu Ile Arg Gln Gln Ile Gly Thr Lys Leu 
        515                 520                 525             


Val Arg Arg Leu Ser Gln Arg Pro Thr Thr Glu Glu Leu Glu Gln Arg 
    530                 535                 540                 


Asn Ile Leu Lys Gln Lys Asn Glu Glu Glu Glu Gln Glu Ala Lys Met 
545                 550                 555                 560 


Glu Leu Lys Arg Arg Leu Ser Arg Lys Leu Ser Leu Arg Pro Thr Val 
                565                 570                 575     


Ala Glu Leu Gln Ala Arg Arg Ile Leu Arg Phe Asn Glu Tyr Val Glu 
            580                 585                 590         


Val Thr Asp Ser Pro Asp Tyr Asp Arg Arg Ala Asp Lys Pro Trp Ala 
        595                 600                 605             


Arg Leu Thr Pro Ala Asp Lys Ala Ala Ile Arg Lys Glu Leu Asn Glu 
    610                 615                 620                 


Phe Lys Ser Thr Glu Met Glu Val His Glu Glu Ser Arg Gln Phe Thr 
625                 630                 635                 640 


Arg Phe His Arg Pro 
                645 


<210>  3546
<211>  801
<212>  PRT
<213>  homo sapiens

<400>  3546

Met His His Arg Met Asn Glu Met Asn Leu Ser Pro Val Gly Met Glu 
1               5                   10                  15      


Gln Leu Thr Ser Ser Ser Val Ser Asn Ala Leu Pro Val Ser Gly Ser 
            20                  25                  30          


His Leu Gly Leu Ala Ala Ser Pro Thr His Ser Ala Ile Pro Ala Pro 
        35                  40                  45              


Gly Leu Pro Val Ala Ile Pro Asn Leu Gly Pro Ser Leu Ser Ser Leu 
    50                  55                  60                  


Pro Ser Ala Leu Ser Leu Met Leu Pro Met Gly Ile Gly Asp Arg Gly 
65                  70                  75                  80  


Val Met Cys Gly Leu Pro Glu Arg Asn Tyr Thr Leu Pro Pro Pro Pro 
                85                  90                  95      


Tyr Pro His Leu Glu Ser Ser Tyr Phe Arg Thr Ile Leu Pro Gly Ile 
            100                 105                 110         


Leu Ser Tyr Leu Ala Asp Arg Pro Pro Pro Gln Tyr Ile His Pro Asn 
        115                 120                 125             


Ser Ile Asn Val Asp Gly Asn Thr Ala Leu Ser Ile Thr Asn Asn Pro 
    130                 135                 140                 


Ser Ala Leu Asp Pro Tyr Gln Ser Asn Gly Asn Val Gly Leu Glu Pro 
145                 150                 155                 160 


Gly Ile Val Ser Ile Asp Ser Arg Ser Val Asn Thr His Gly Ala Gln 
                165                 170                 175     


Ser Leu His Pro Ser Asp Gly His Glu Val Ala Leu Asp Thr Ala Ile 
            180                 185                 190         


Thr Met Glu Asn Val Ser Arg Val Thr Ser Pro Ile Ser Thr Asp Gly 
        195                 200                 205             


Met Ala Glu Glu Leu Thr Met Asp Gly Val Ala Gly Glu His Ser Gln 
    210                 215                 220                 


Ile Pro Asn Gly Ser Arg Ser His Glu Pro Leu Ser Val Asp Ser Val 
225                 230                 235                 240 


Ser Asn Asn Leu Ala Ala Asp Ala Val Gly His Gly Gly Val Ile Pro 
                245                 250                 255     


Met His Gly Asn Gly Leu Glu Leu Pro Val Val Met Glu Thr Asp His 
            260                 265                 270         


Ile Ala Ser Arg Val Asn Gly Met Ser Asp Ser Ala Leu Ser Asp Ser 
        275                 280                 285             


Ile His Thr Val Ala Met Ser Thr Asn Ser Val Ser Val Ala Leu Ser 
    290                 295                 300                 


Thr Ser His Asn Leu Ala Ser Leu Glu Ser Val Ser Leu His Glu Val 
305                 310                 315                 320 


Gly Leu Ser Leu Glu Pro Val Ala Val Ser Ser Ile Thr Gln Glu Val 
                325                 330                 335     


Ala Met Gly Thr Gly His Val Asp Val Ser Ser Asp Ser Leu Ser Phe 
            340                 345                 350         


Val Ser Pro Ser Leu Gln Met Glu Asp Ser Asn Ser Asn Lys Glu Asn 
        355                 360                 365             


Met Ala Thr Leu Phe Thr Ile Trp Cys Thr Leu Cys Asp Arg Ala Tyr 
    370                 375                 380                 


Pro Ser Asp Cys Pro Glu His Gly Pro Val Thr Phe Val Pro Asp Thr 
385                 390                 395                 400 


Pro Ile Glu Ser Arg Ala Arg Leu Ser Leu Pro Lys Gln Leu Val Leu 
                405                 410                 415     


Arg Gln Ser Ile Val Gly Ala Glu Val Gly Val Trp Thr Gly Glu Thr 
            420                 425                 430         


Ile Pro Val Arg Thr Cys Phe Gly Pro Leu Ile Gly Gln Gln Ser His 
        435                 440                 445             


Ser Met Glu Val Ala Glu Trp Thr Asp Lys Ala Val Asn His Ile Trp 
    450                 455                 460                 


Lys Ile Tyr His Asn Gly Val Leu Glu Phe Cys Ile Ile Thr Thr Asp 
465                 470                 475                 480 


Glu Asn Glu Cys Asn Trp Met Met Phe Val Arg Lys Ala Arg Asn Arg 
                485                 490                 495     


Glu Glu Gln Asn Leu Val Ala Tyr Pro His Asp Gly Lys Ile Phe Phe 
            500                 505                 510         


Cys Thr Ser Gln Asp Ile Pro Pro Glu Asn Glu Leu Leu Phe Tyr Tyr 
        515                 520                 525             


Ser Arg Asp Tyr Ala Gln Gln Ile Gly Val Pro Glu His Pro Asp Val 
    530                 535                 540                 


His Leu Cys Asn Cys Gly Lys Glu Cys Asn Ser Tyr Thr Glu Phe Lys 
545                 550                 555                 560 


Ala His Leu Thr Ser His Ile His Asn His Leu Pro Thr Gln Gly His 
                565                 570                 575     


Ser Gly Ser His Gly Pro Ser His Ser Lys Glu Arg Lys Trp Lys Cys 
            580                 585                 590         


Ser Met Cys Pro Gln Ala Phe Ile Ser Pro Ser Lys Leu His Val His 
        595                 600                 605             


Phe Met Gly His Met Gly Met Lys Pro His Lys Cys Asp Phe Cys Ser 
    610                 615                 620                 


Lys Ala Phe Ser Asp Pro Ser Asn Leu Arg Thr His Leu Lys Ile His 
625                 630                 635                 640 


Thr Gly Gln Lys Asn Tyr Arg Cys Thr Leu Cys Asp Lys Ser Phe Thr 
                645                 650                 655     


Gln Lys Ala His Leu Glu Ser His Met Val Ile His Thr Gly Glu Lys 
            660                 665                 670         


Asn Leu Lys Cys Asp Tyr Cys Asp Lys Leu Phe Met Arg Arg Gln Asp 
        675                 680                 685             


Leu Lys Gln His Val Leu Ile His Thr Gln Glu Arg Gln Ile Lys Cys 
    690                 695                 700                 


Pro Lys Cys Asp Lys Leu Phe Leu Arg Thr Asn His Leu Lys Lys His 
705                 710                 715                 720 


Leu Asn Ser His Glu Gly Lys Arg Asp Tyr Val Cys Glu Lys Cys Thr 
                725                 730                 735     


Lys Ala Tyr Leu Thr Lys Tyr His Leu Thr Arg His Leu Lys Thr Cys 
            740                 745                 750         


Lys Gly Pro Thr Ser Ser Ser Ser Ala Pro Glu Glu Glu Glu Glu Asp 
        755                 760                 765             


Asp Ser Glu Glu Glu Asp Leu Ala Asp Ser Val Gly Thr Glu Asp Cys 
    770                 775                 780                 


Arg Ile Asn Ser Ala Val Tyr Ser Ala Asp Glu Ser Leu Ser Ala His 
785                 790                 795                 800 


Lys 
    


<210>  3547
<211>  344
<212>  PRT
<213>  homo sapiens

<400>  3547

Met Lys Asp Leu Gly Ala Glu His Leu Ala Gly His Glu Gly Val Gln 
1               5                   10                  15      


Leu Leu Gly Leu Leu Asn Val Tyr Leu Glu Gln Glu Glu Arg Phe Gln 
            20                  25                  30          


Pro Arg Glu Lys Gly Leu Ser Leu Ile Glu Ala Thr Pro Glu Asn Asp 
        35                  40                  45              


Asn Thr Leu Cys Pro Gly Leu Arg Asn Ala Lys Val Glu Asp Leu Arg 
    50                  55                  60                  


Ser Leu Ala Asn Phe Phe Gly Ser Cys Thr Glu Thr Phe Val Leu Ala 
65                  70                  75                  80  


Val Asn Ile Leu Asp Arg Phe Leu Ala Leu Met Lys Val Lys Pro Lys 
                85                  90                  95      


His Leu Ser Cys Ile Gly Val Cys Ser Phe Leu Leu Ala Ala Arg Ile 
            100                 105                 110         


Val Glu Glu Asp Cys Asn Ile Pro Ser Thr His Asp Val Ile Arg Ile 
        115                 120                 125             


Ser Gln Cys Lys Cys Thr Ala Ser Asp Ile Lys Arg Met Glu Lys Ile 
    130                 135                 140                 


Ile Ser Glu Lys Leu His Tyr Glu Leu Glu Ala Thr Thr Ala Leu Asn 
145                 150                 155                 160 


Phe Leu His Leu Tyr His Thr Ile Ile Leu Cys His Thr Ser Glu Arg 
                165                 170                 175     


Lys Glu Ile Leu Ser Leu Asp Lys Leu Glu Ala Gln Leu Lys Ala Cys 
            180                 185                 190         


Asn Cys Arg Leu Ile Phe Ser Lys Ala Lys Pro Ser Val Leu Ala Leu 
        195                 200                 205             


Cys Leu Leu Asn Leu Glu Val Glu Thr Leu Lys Ser Val Glu Leu Leu 
    210                 215                 220                 


Glu Ile Leu Leu Leu Val Lys Lys His Ser Lys Ile Asn Asp Thr Glu 
225                 230                 235                 240 


Phe Phe Tyr Trp Arg Glu Leu Val Ser Lys Cys Leu Ala Glu Tyr Ser 
                245                 250                 255     


Ser Pro Glu Cys Cys Lys Pro Asp Leu Lys Lys Leu Val Trp Ile Val 
            260                 265                 270         


Ser Arg Arg Thr Ala Gln Asn Leu His Asn Ser Tyr Tyr Ser Val Pro 
        275                 280                 285             


Glu Leu Pro Thr Ile Pro Glu Gly Gly Cys Phe Asp Glu Ser Glu Ser 
    290                 295                 300                 


Glu Asp Ser Cys Glu Asp Met Ser Cys Gly Glu Glu Ser Leu Ser Ser 
305                 310                 315                 320 


Ser Pro Pro Ser Asp Gln Glu Cys Thr Phe Phe Phe Asn Phe Lys Val 
                325                 330                 335     


Ala Gln Thr Leu Cys Phe Pro Ser 
            340                 


<210>  3548
<211>  118
<212>  PRT
<213>  homo sapiens

<400>  3548

Met Ser Ser Lys Arg Ala Lys Ala Lys Thr Thr Lys Lys Arg Pro Gln 
1               5                   10                  15      


Arg Ala Thr Ser Asn Val Phe Ala Met Phe Asp Gln Ser Gln Ile Gln 
            20                  25                  30          


Glu Phe Lys Glu Ala Phe Asn Met Ile Asp Gln Asn Arg Asp Gly Phe 
        35                  40                  45              


Ile Asp Lys Glu Asp Leu His Asp Met Leu Ala Ser Leu Gly Phe Ile 
    50                  55                  60                  


His Glu Asp His Leu Arg Glu Leu Leu Thr Thr Met Gly Asp Arg Phe 
65                  70                  75                  80  


Thr Asp Glu Glu Val Asp Glu Met Tyr Arg Glu Ala Pro Ile Asp Lys 
                85                  90                  95      


Lys Gly Asn Phe Asn Tyr Val Glu Phe Thr Arg Ile Leu Lys His Gly 
            100                 105                 110         


Ala Lys Asp Lys Asp Asp 
        115             


<210>  3549
<211>  153
<212>  PRT
<213>  homo sapiens

<400>  3549

Met Ala Met Ile Ser Gly Leu Ser Gly Arg Lys Ser Ser Thr Gly Ser 
1               5                   10                  15      


Pro Thr Ser Pro Leu Asn Ala Glu Lys Leu Glu Ser Glu Asp Val Ser 
            20                  25                  30          


Gln Ala Phe Leu Glu Ala Val Ala Glu Glu Lys Pro His Val Lys Pro 
        35                  40                  45              


Tyr Phe Ser Lys Thr Ile Arg Asp Leu Glu Val Val Glu Gly Ser Ala 
    50                  55                  60                  


Ala Arg Phe Asp Cys Lys Ile Glu Gly Tyr Pro Asp Pro Glu Val Val 
65                  70                  75                  80  


Trp Phe Lys Asp Asp Gln Ser Ile Arg Glu Ser Arg His Phe Gln Ile 
                85                  90                  95      


Asp Tyr Asp Glu Asp Gly Asn Cys Ser Leu Ile Ile Ser Asp Val Cys 
            100                 105                 110         


Gly Asp Asp Asp Ala Lys Tyr Thr Cys Lys Ala Val Asn Ser Leu Gly 
        115                 120                 125             


Glu Ala Thr Cys Thr Ala Glu Leu Ile Val Glu Thr Met Glu Glu Gly 
    130                 135                 140                 


Glu Gly Glu Gly Glu Glu Glu Glu Glu 
145                 150             


<210>  3550
<211>  632
<212>  PRT
<213>  homo sapiens

<400>  3550

Met Asp Thr Met Met Leu Asn Val Arg Asn Leu Phe Glu Gln Leu Val 
1               5                   10                  15      


Arg Arg Val Glu Ile Leu Ser Glu Gly Asn Glu Val Gln Phe Ile Gln 
            20                  25                  30          


Leu Ala Lys Asp Phe Glu Asp Phe Arg Lys Lys Trp Gln Arg Thr Asp 
        35                  40                  45              


His Glu Leu Gly Lys Tyr Lys Asp Leu Leu Met Lys Ala Glu Thr Glu 
    50                  55                  60                  


Arg Ser Ala Leu Asp Val Lys Leu Lys His Ala Arg Asn Gln Val Asp 
65                  70                  75                  80  


Val Glu Ile Lys Arg Arg Gln Arg Ala Glu Ala Asp Cys Glu Lys Leu 
                85                  90                  95      


Glu Arg Gln Ile Gln Leu Ile Arg Glu Met Leu Met Cys Asp Thr Ser 
            100                 105                 110         


Gly Ser Ile Gln Leu Ser Glu Glu Gln Lys Ser Ala Leu Ala Phe Leu 
        115                 120                 125             


Asn Arg Gly Gln Pro Ser Ser Ser Asn Ala Gly Asn Lys Arg Leu Ser 
    130                 135                 140                 


Thr Ile Asp Glu Ser Gly Ser Ile Leu Ser Asp Ile Ser Phe Asp Lys 
145                 150                 155                 160 


Thr Asp Glu Ser Leu Asp Trp Asp Ser Ser Leu Val Lys Thr Phe Lys 
                165                 170                 175     


Leu Lys Lys Arg Glu Lys Arg Arg Ser Thr Ser Arg Gln Phe Val Asp 
            180                 185                 190         


Gly Pro Pro Gly Pro Val Lys Lys Thr Arg Ser Ile Gly Ser Ala Val 
        195                 200                 205             


Asp Gln Gly Asn Glu Ser Ile Val Ala Lys Thr Thr Val Thr Val Pro 
    210                 215                 220                 


Asn Asp Gly Gly Pro Ile Glu Ala Val Ser Thr Ile Glu Thr Val Pro 
225                 230                 235                 240 


Tyr Trp Thr Arg Ser Arg Arg Lys Thr Gly Thr Leu Gln Pro Trp Asn 
                245                 250                 255     


Ser Asp Ser Thr Leu Asn Ser Arg Gln Leu Glu Pro Arg Thr Glu Thr 
            260                 265                 270         


Asp Ser Val Gly Thr Pro Gln Ser Asn Gly Gly Met Arg Leu His Asp 
        275                 280                 285             


Phe Val Ser Lys Thr Val Ile Lys Pro Glu Ser Cys Val Pro Cys Gly 
    290                 295                 300                 


Lys Arg Ile Lys Phe Gly Lys Leu Ser Leu Lys Cys Arg Asp Cys Arg 
305                 310                 315                 320 


Val Val Ser His Pro Glu Cys Arg Asp Arg Cys Pro Leu Pro Cys Ile 
                325                 330                 335     


Pro Thr Leu Ile Gly Thr Pro Val Lys Ile Gly Glu Gly Met Leu Ala 
            340                 345                 350         


Asp Phe Val Ser Gln Thr Ser Pro Met Ile Pro Ser Ile Val Val His 
        355                 360                 365             


Cys Val Asn Glu Ile Glu Gln Arg Gly Leu Thr Glu Thr Gly Leu Tyr 
    370                 375                 380                 


Arg Ile Ser Gly Cys Asp Arg Thr Val Lys Glu Leu Lys Glu Lys Phe 
385                 390                 395                 400 


Leu Arg Val Lys Thr Val Pro Leu Leu Ser Lys Val Asp Asp Ile His 
                405                 410                 415     


Ala Ile Cys Ser Leu Leu Lys Asp Phe Leu Arg Asn Leu Lys Glu Pro 
            420                 425                 430         


Leu Leu Thr Phe Arg Leu Asn Arg Ala Phe Met Glu Ala Ala Glu Ile 
        435                 440                 445             


Thr Asp Glu Asp Asn Ser Ile Ala Ala Met Tyr Gln Ala Val Gly Glu 
    450                 455                 460                 


Leu Pro Gln Ala Asn Arg Asp Thr Leu Ala Phe Leu Met Ile His Leu 
465                 470                 475                 480 


Gln Arg Val Ala Gln Ser Pro His Thr Lys Met Asp Val Ala Asn Leu 
                485                 490                 495     


Ala Lys Val Phe Gly Pro Thr Ile Val Ala His Ala Val Pro Asn Pro 
            500                 505                 510         


Asp Pro Val Thr Met Leu Gln Asp Ile Lys Arg Gln Pro Lys Val Val 
        515                 520                 525             


Glu Arg Leu Leu Ser Leu Pro Leu Glu Tyr Trp Ser Gln Phe Met Met 
    530                 535                 540                 


Val Glu Gln Glu Asn Ile Asp Pro Leu His Val Ile Glu Asn Ser Asn 
545                 550                 555                 560 


Ala Phe Ser Thr Pro Gln Thr Pro Asp Ile Lys Val Ser Leu Leu Gly 
                565                 570                 575     


Pro Val Thr Thr Pro Glu His Gln Leu Leu Lys Thr Pro Ser Ser Ser 
            580                 585                 590         


Ser Leu Ser Gln Arg Val Arg Ser Thr Leu Thr Lys Asn Thr Pro Arg 
        595                 600                 605             


Phe Gly Ser Lys Ser Lys Ser Ala Thr Asn Leu Gly Arg Gln Gly Asn 
    610                 615                 620                 


Phe Phe Ala Ser Pro Met Leu Lys 
625                 630         


<210>  3551
<211>  694
<212>  PRT
<213>  homo sapiens

<400>  3551

Met Gly Ala Pro Ala Cys Ala Leu Ala Leu Cys Val Ala Val Ala Ile 
1               5                   10                  15      


Val Ala Gly Ala Ser Ser Glu Ser Leu Gly Thr Glu Gln Arg Val Val 
            20                  25                  30          


Gly Arg Ala Ala Glu Val Pro Gly Pro Glu Pro Gly Gln Gln Glu Gln 
        35                  40                  45              


Leu Val Phe Gly Ser Gly Asp Ala Val Glu Leu Ser Cys Pro Pro Pro 
    50                  55                  60                  


Gly Gly Gly Pro Met Gly Pro Thr Val Trp Val Lys Asp Gly Thr Gly 
65                  70                  75                  80  


Leu Val Pro Ser Glu Arg Val Leu Val Gly Pro Gln Arg Leu Gln Val 
                85                  90                  95      


Leu Asn Ala Ser His Glu Asp Ser Gly Ala Tyr Ser Cys Arg Gln Arg 
            100                 105                 110         


Leu Thr Gln Arg Val Leu Cys His Phe Ser Val Arg Val Thr Asp Ala 
        115                 120                 125             


Pro Ser Ser Gly Asp Asp Glu Asp Gly Glu Asp Glu Ala Glu Asp Thr 
    130                 135                 140                 


Gly Val Asp Thr Gly Ala Pro Tyr Trp Thr Arg Pro Glu Arg Met Asp 
145                 150                 155                 160 


Lys Lys Leu Leu Ala Val Pro Ala Ala Asn Thr Val Arg Phe Arg Cys 
                165                 170                 175     


Pro Ala Ala Gly Asn Pro Thr Pro Ser Ile Ser Trp Leu Lys Asn Gly 
            180                 185                 190         


Arg Glu Phe Arg Gly Glu His Arg Ile Gly Gly Ile Lys Leu Arg His 
        195                 200                 205             


Gln Gln Trp Ser Leu Val Met Glu Ser Val Val Pro Ser Asp Arg Gly 
    210                 215                 220                 


Asn Tyr Thr Cys Val Val Glu Asn Lys Phe Gly Ser Ile Arg Gln Thr 
225                 230                 235                 240 


Tyr Thr Leu Asp Val Leu Glu Arg Ser Pro His Arg Pro Ile Leu Gln 
                245                 250                 255     


Ala Gly Leu Pro Ala Asn Gln Thr Ala Val Leu Gly Ser Asp Val Glu 
            260                 265                 270         


Phe His Cys Lys Val Tyr Ser Asp Ala Gln Pro His Ile Gln Trp Leu 
        275                 280                 285             


Lys His Val Glu Val Asn Gly Ser Lys Val Gly Pro Asp Gly Thr Pro 
    290                 295                 300                 


Tyr Val Thr Val Leu Lys Val Ser Leu Glu Ser Asn Ala Ser Met Ser 
305                 310                 315                 320 


Ser Asn Thr Pro Leu Val Arg Ile Ala Arg Leu Ser Ser Gly Glu Gly 
                325                 330                 335     


Pro Thr Leu Ala Asn Val Ser Glu Leu Glu Leu Pro Ala Asp Pro Lys 
            340                 345                 350         


Trp Glu Leu Ser Arg Ala Arg Leu Thr Leu Gly Lys Pro Leu Gly Glu 
        355                 360                 365             


Gly Cys Phe Gly Gln Val Val Met Ala Glu Ala Ile Gly Ile Asp Lys 
    370                 375                 380                 


Asp Arg Ala Ala Lys Pro Val Thr Val Ala Val Lys Met Leu Lys Asp 
385                 390                 395                 400 


Asp Ala Thr Asp Lys Asp Leu Ser Asp Leu Val Ser Glu Met Glu Met 
                405                 410                 415     


Met Lys Met Ile Gly Lys His Lys Asn Ile Ile Asn Leu Leu Gly Ala 
            420                 425                 430         


Cys Thr Gln Gly Gly Pro Leu Tyr Val Leu Val Glu Tyr Ala Ala Lys 
        435                 440                 445             


Gly Asn Leu Arg Glu Phe Leu Arg Ala Arg Arg Pro Pro Gly Leu Asp 
    450                 455                 460                 


Tyr Ser Phe Asp Thr Cys Lys Pro Pro Glu Glu Gln Leu Thr Phe Lys 
465                 470                 475                 480 


Asp Leu Val Ser Cys Ala Tyr Gln Val Ala Arg Gly Met Glu Tyr Leu 
                485                 490                 495     


Ala Ser Gln Lys Cys Ile His Arg Asp Leu Ala Ala Arg Asn Val Leu 
            500                 505                 510         


Val Thr Glu Asp Asn Val Met Lys Ile Ala Asp Phe Gly Leu Ala Arg 
        515                 520                 525             


Asp Val His Asn Leu Asp Tyr Tyr Lys Lys Thr Thr Asn Gly Arg Leu 
    530                 535                 540                 


Pro Val Lys Trp Met Ala Pro Glu Ala Leu Phe Asp Arg Val Tyr Thr 
545                 550                 555                 560 


His Gln Ser Asp Val Trp Ser Phe Gly Val Leu Leu Trp Glu Ile Phe 
                565                 570                 575     


Thr Leu Gly Gly Ser Pro Tyr Pro Gly Ile Pro Val Glu Glu Leu Phe 
            580                 585                 590         


Lys Leu Leu Lys Glu Gly His Arg Met Asp Lys Pro Ala Asn Cys Thr 
        595                 600                 605             


His Asp Leu Tyr Met Ile Met Arg Glu Cys Trp His Ala Ala Pro Ser 
    610                 615                 620                 


Gln Arg Pro Thr Phe Lys Gln Leu Val Glu Asp Leu Asp Arg Val Leu 
625                 630                 635                 640 


Thr Val Thr Ser Thr Asp Glu Tyr Leu Asp Leu Ser Ala Pro Phe Glu 
                645                 650                 655     


Gln Tyr Ser Pro Gly Gly Gln Asp Thr Pro Ser Ser Ser Ser Ser Gly 
            660                 665                 670         


Asp Asp Ser Val Phe Ala His Asp Leu Leu Pro Pro Ala Pro Pro Ser 
        675                 680                 685             


Ser Gly Gly Ser Arg Thr 
    690                 


<210>  3552
<211>  354
<212>  PRT
<213>  homo sapiens

<400>  3552

Met Ser Thr Glu Gly Gly Phe Gly Gly Thr Ser Ser Ser Asp Ala Gln 
1               5                   10                  15      


Gln Ser Leu Gln Ser Phe Trp Pro Arg Val Met Glu Glu Ile Arg Asn 
            20                  25                  30          


Leu Thr Val Lys Asp Phe Arg Val Gln Glu Leu Pro Leu Ala Arg Ile 
        35                  40                  45              


Lys Lys Ile Met Lys Leu Asp Glu Asp Val Lys Met Ile Ser Ala Glu 
    50                  55                  60                  


Ala Pro Val Leu Phe Ala Lys Ala Ala Gln Ile Phe Ile Thr Glu Leu 
65                  70                  75                  80  


Thr Leu Arg Ala Trp Ile His Thr Glu Asp Asn Lys Arg Arg Thr Leu 
                85                  90                  95      


Gln Arg Asn Asp Ile Ala Met Ala Ile Thr Lys Phe Asp Gln Phe Asp 
            100                 105                 110         


Phe Leu Ile Asp Ile Val Pro Arg Asp Glu Leu Lys Pro Pro Lys Arg 
        115                 120                 125             


Gln Glu Glu Val Arg Gln Ser Val Thr Pro Ala Glu Pro Val Gln Tyr 
    130                 135                 140                 


Tyr Phe Thr Leu Ala Gln Gln Pro Thr Ala Val Gln Val Gln Gly Gln 
145                 150                 155                 160 


Gln Gln Gly Gln Gln Thr Thr Ser Ser Thr Thr Thr Ile Gln Pro Gly 
                165                 170                 175     


Gln Ile Ile Ile Ala Gln Pro Gln Gln Gly Gln Thr Thr Pro Val Thr 
            180                 185                 190         


Met Gln Val Gly Glu Gly Gln Gln Val Gln Ile Val Gln Ala Gln Pro 
        195                 200                 205             


Gln Gly Gln Ala Gln Gln Ala Gln Ser Gly Thr Gly Gln Thr Met Gln 
    210                 215                 220                 


Val Met Gln Gln Ile Ile Thr Asn Thr Gly Glu Ile Gln Gln Ile Pro 
225                 230                 235                 240 


Val Gln Leu Asn Ala Gly Gln Leu Gln Tyr Ile Arg Leu Ala Gln Pro 
                245                 250                 255     


Val Ser Gly Thr Gln Val Val Gln Gly Gln Ile Gln Thr Leu Ala Thr 
            260                 265                 270         


Asn Ala Gln Gln Gly Gln Arg Asn Ala Ser Gln Gly Lys Pro Arg Arg 
        275                 280                 285             


Cys Leu Lys Glu Thr Leu Gln Ile Thr Gln Thr Glu Val Gln Gln Gly 
    290                 295                 300                 


Gln Gln Gln Phe Ser Gln Phe Thr Asp Gly Gln Gln Leu Tyr Gln Ile 
305                 310                 315                 320 


Gln Gln Val Thr Met Pro Ala Gly Gln Asp Leu Ala Gln Pro Met Phe 
                325                 330                 335     


Ile Gln Ser Ala Asn Gln Pro Ser Asp Gly Gln Ala Pro Gln Val Thr 
            340                 345                 350         


Gly Asp 
        


<210>  3553
<211>  297
<212>  PRT
<213>  homo sapiens

<400>  3553

Met Ser Thr Glu Gly Gly Phe Gly Gly Thr Ser Ser Ser Asp Ala Gln 
1               5                   10                  15      


Gln Ser Leu Gln Ser Phe Trp Pro Arg Val Met Glu Glu Ile Arg Asn 
            20                  25                  30          


Leu Thr Val Lys Asp Phe Arg Val Gln Glu Leu Pro Leu Ala Arg Ile 
        35                  40                  45              


Lys Lys Ile Met Lys Leu Asp Glu Asp Val Lys Arg Asn Asp Ile Ala 
    50                  55                  60                  


Met Ala Ile Thr Lys Phe Asp Gln Phe Asp Phe Leu Ile Asp Ile Val 
65                  70                  75                  80  


Pro Arg Asp Glu Leu Lys Pro Pro Lys Arg Gln Glu Glu Val Arg Gln 
                85                  90                  95      


Ser Val Thr Pro Ala Glu Pro Val Gln Tyr Tyr Phe Thr Leu Ala Gln 
            100                 105                 110         


Gln Pro Thr Ala Val Gln Val Gln Gly Gln Gln Gln Gly Gln Gln Thr 
        115                 120                 125             


Thr Ser Ser Thr Thr Thr Ile Gln Pro Gly Gln Ile Ile Ile Ala Gln 
    130                 135                 140                 


Pro Gln Gln Gly Gln Thr Thr Pro Val Thr Met Gln Val Gly Glu Gly 
145                 150                 155                 160 


Gln Gln Val Gln Ile Val Gln Ala Gln Pro Gln Gly Gln Ala Gln Gln 
                165                 170                 175     


Ala Gln Ser Gly Thr Gly Gln Thr Met Gln Val Met Gln Gln Ile Ile 
            180                 185                 190         


Thr Asn Thr Gly Glu Ile Gln Gln Ile Pro Val Gln Leu Asn Ala Gly 
        195                 200                 205             


Gln Leu Gln Tyr Ile Arg Leu Ala Gln Pro Val Ser Gly Thr Gln Val 
    210                 215                 220                 


Val Gln Gly Gln Ile Gln Thr Leu Ala Thr Asn Ala Gln Gln Ile Thr 
225                 230                 235                 240 


Gln Thr Glu Val Gln Gln Gly Gln Gln Gln Phe Ser Gln Phe Thr Asp 
                245                 250                 255     


Gly Gln Gln Leu Tyr Gln Ile Gln Gln Val Thr Met Pro Ala Gly Gln 
            260                 265                 270         


Asp Leu Ala Gln Pro Met Phe Ile Gln Ser Ala Asn Gln Pro Ser Asp 
        275                 280                 285             


Gly Gln Ala Pro Gln Val Thr Gly Asp 
    290                 295         


<210>  3554
<211>  301
<212>  PRT
<213>  homo sapiens

<400>  3554

Met Ser Thr Glu Gly Gly Phe Gly Gly Thr Ser Ser Ser Asp Ala Gln 
1               5                   10                  15      


Gln Ser Leu Gln Ser Phe Trp Pro Arg Val Met Glu Glu Ile Arg Asn 
            20                  25                  30          


Leu Thr Val Lys Asp Phe Arg Val Gln Glu Leu Pro Leu Ala Arg Ile 
        35                  40                  45              


Lys Lys Ile Met Lys Leu Asp Glu Asp Val Lys Met Ile Ser Ala Glu 
    50                  55                  60                  


Ala Pro Val Leu Phe Ala Lys Ala Ala Gln Ile Phe Ile Thr Glu Leu 
65                  70                  75                  80  


Thr Leu Arg Ala Trp Ile His Thr Glu Asp Asn Lys Arg Arg Thr Leu 
                85                  90                  95      


Gln Arg Asn Asp Ile Ala Met Ala Ile Thr Lys Phe Asp Gln Phe Asp 
            100                 105                 110         


Phe Leu Ile Asp Ile Val Pro Arg Asp Glu Leu Lys Pro Pro Lys Arg 
        115                 120                 125             


Gln Glu Glu Val Arg Gln Ser Val Thr Pro Ala Glu Pro Val Gln Tyr 
    130                 135                 140                 


Tyr Phe Thr Leu Ala Gln Gln Pro Thr Ala Val Gln Val Gln Gly Gln 
145                 150                 155                 160 


Gln Gln Gly Gln Gln Thr Thr Ser Ser Thr Thr Thr Ile Gln Pro Gly 
                165                 170                 175     


Gln Ile Ile Ile Ala Gln Pro Gln Gln Gly Gln Thr Met Gln Val Met 
            180                 185                 190         


Gln Gln Ile Ile Thr Asn Thr Gly Glu Ile Gln Gln Ile Pro Val Gln 
        195                 200                 205             


Leu Asn Ala Gly Gln Leu Gln Tyr Ile Arg Leu Ala Gln Pro Val Ser 
    210                 215                 220                 


Gly Thr Gln Val Val Gln Gly Gln Ile Gln Thr Leu Ala Thr Asn Ala 
225                 230                 235                 240 


Gln Gln Ile Thr Gln Thr Glu Val Gln Gln Gly Gln Gln Gln Phe Ser 
                245                 250                 255     


Gln Phe Thr Asp Gly Gln Gln Leu Tyr Gln Ile Gln Gln Val Thr Met 
            260                 265                 270         


Pro Ala Gly Gln Asp Leu Ala Gln Pro Met Phe Ile Gln Ser Ala Asn 
        275                 280                 285             


Gln Pro Ser Asp Gly Gln Ala Pro Gln Val Thr Gly Asp 
    290                 295                 300     


<210>  3555
<211>  133
<212>  PRT
<213>  homo sapiens

<400>  3555

Met Met Leu Asn Ser Asp Thr Met Glu Leu Asp Leu Pro Pro Thr His 
1               5                   10                  15      


Ser Glu Thr Glu Ser Gly Phe Ser Asp Cys Gly Gly Gly Ala Gly Pro 
            20                  25                  30          


Asp Gly Ala Gly Pro Gly Gly Pro Gly Gly Gly Gln Ala Arg Gly Pro 
        35                  40                  45              


Glu Pro Gly Glu Pro Gly Arg Lys Asp Leu Gln His Leu Ser Arg Glu 
    50                  55                  60                  


Glu Arg Arg Arg Arg Arg Arg Ala Thr Ala Lys Tyr Arg Thr Ala His 
65                  70                  75                  80  


Ala Thr Arg Glu Arg Ile Arg Val Glu Ala Phe Asn Leu Ala Phe Ala 
                85                  90                  95      


Glu Leu Arg Lys Leu Leu Pro Thr Leu Pro Pro Asp Lys Lys Leu Ser 
            100                 105                 110         


Lys Ile Glu Ile Leu Arg Leu Ala Ile Cys Tyr Ile Ser Tyr Leu Asn 
        115                 120                 125             


His Val Leu Asp Val 
    130             


<210>  3556
<211>  2236
<212>  PRT
<213>  homo sapiens

<400>  3556

Met Ala His Asn Ala Gly Ala Ala Ala Ala Ala Gly Thr His Ser Ala 
1               5                   10                  15      


Lys Ser Gly Gly Ser Glu Ala Ala Leu Lys Glu Gly Gly Ser Ala Ala 
            20                  25                  30          


Ala Leu Ser Ser Ser Ser Ser Ser Ser Ala Ala Ala Ala Ala Ala Ser 
        35                  40                  45              


Ser Ser Ser Ser Ser Gly Pro Gly Ser Ala Met Glu Thr Gly Leu Leu 
    50                  55                  60                  


Pro Asn His Lys Leu Lys Thr Val Gly Glu Ala Pro Ala Ala Pro Pro 
65                  70                  75                  80  


His Gln Gln His His His His His His Ala His His His His His His 
                85                  90                  95      


Ala His His Leu His His His His Ala Leu Gln Gln Gln Leu Asn Gln 
            100                 105                 110         


Phe Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln 
        115                 120                 125             


Gln Gln Gln His Pro Ile Ser Asn Asn Asn Ser Leu Gly Gly Ala Gly 
    130                 135                 140                 


Gly Gly Ala Pro Gln Pro Gly Pro Asp Met Glu Gln Pro Gln His Gly 
145                 150                 155                 160 


Gly Ala Lys Asp Ser Ala Ala Gly Gly Gln Ala Asp Pro Pro Gly Pro 
                165                 170                 175     


Pro Leu Leu Ser Lys Pro Gly Asp Glu Asp Asp Ala Pro Pro Lys Met 
            180                 185                 190         


Gly Glu Pro Ala Gly Gly Arg Tyr Glu His Pro Gly Leu Gly Ala Leu 
        195                 200                 205             


Gly Thr Gln Gln Pro Pro Val Ala Val Pro Gly Gly Gly Gly Gly Pro 
    210                 215                 220                 


Ala Ala Val Pro Glu Phe Asn Asn Tyr Tyr Gly Ser Ala Ala Pro Ala 
225                 230                 235                 240 


Ser Gly Gly Pro Gly Gly Arg Ala Gly Pro Cys Phe Asp Gln His Gly 
                245                 250                 255     


Gly Gln Gln Ser Pro Gly Met Gly Met Met His Ser Ala Ser Ala Ala 
            260                 265                 270         


Ala Ala Gly Ala Pro Gly Ser Met Asp Pro Leu Gln Asn Ser His Glu 
        275                 280                 285             


Gly Tyr Pro Asn Ser Gln Cys Asn His Tyr Pro Gly Tyr Ser Arg Pro 
    290                 295                 300                 


Gly Ala Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ser 
305                 310                 315                 320 


Gly Gly Gly Gly Gly Gly Gly Gly Ala Gly Ala Gly Gly Ala Gly Ala 
                325                 330                 335     


Gly Ala Val Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Gly Gly 
            340                 345                 350         


Gly Gly Gly Gly Gly Tyr Gly Gly Ser Ser Ala Gly Tyr Gly Val Leu 
        355                 360                 365             


Ser Ser Pro Arg Gln Gln Gly Gly Gly Met Met Met Gly Pro Gly Gly 
    370                 375                 380                 


Gly Gly Ala Ala Ser Leu Ser Lys Ala Ala Ala Gly Ser Ala Ala Gly 
385                 390                 395                 400 


Gly Phe Gln Arg Phe Ala Gly Gln Asn Gln His Pro Ser Gly Ala Thr 
                405                 410                 415     


Pro Thr Leu Asn Gln Leu Leu Thr Ser Pro Ser Pro Met Met Arg Ser 
            420                 425                 430         


Tyr Gly Gly Ser Tyr Pro Glu Tyr Ser Ser Pro Ser Ala Pro Pro Pro 
        435                 440                 445             


Pro Pro Ser Gln Pro Gln Ser Gln Ala Ala Ala Ala Gly Ala Ala Ala 
    450                 455                 460                 


Gly Gly Gln Gln Ala Ala Ala Gly Met Gly Leu Gly Lys Asp Met Gly 
465                 470                 475                 480 


Ala Gln Tyr Ala Ala Ala Ser Pro Ala Trp Ala Ala Ala Gln Gln Arg 
                485                 490                 495     


Ser His Pro Ala Met Ser Pro Gly Thr Pro Gly Pro Thr Met Gly Arg 
            500                 505                 510         


Ser Gln Gly Ser Pro Met Asp Pro Met Val Met Lys Arg Pro Gln Leu 
        515                 520                 525             


Tyr Gly Met Gly Ser Asn Pro His Ser Gln Pro Gln Gln Ser Ser Pro 
    530                 535                 540                 


Tyr Pro Gly Gly Ser Tyr Gly Pro Pro Gly Pro Gln Arg Tyr Pro Ile 
545                 550                 555                 560 


Gly Ile Gln Gly Arg Thr Pro Gly Ala Met Ala Gly Met Gln Tyr Pro 
                565                 570                 575     


Gln Gln Gln Met Pro Pro Gln Tyr Gly Gln Gln Gly Val Ser Gly Tyr 
            580                 585                 590         


Cys Gln Gln Gly Gln Gln Pro Tyr Tyr Ser Gln Gln Pro Gln Pro Pro 
        595                 600                 605             


His Leu Pro Pro Gln Ala Gln Tyr Leu Pro Ser Gln Ser Gln Gln Arg 
    610                 615                 620                 


Tyr Gln Pro Gln Gln Asp Met Ser Gln Glu Gly Tyr Gly Thr Arg Ser 
625                 630                 635                 640 


Gln Pro Pro Leu Ala Pro Gly Lys Pro Asn His Glu Asp Leu Asn Leu 
                645                 650                 655     


Ile Gln Gln Glu Arg Pro Ser Ser Leu Pro Asp Leu Ser Gly Ser Ile 
            660                 665                 670         


Asp Asp Leu Pro Thr Gly Thr Glu Ala Thr Leu Ser Ser Ala Val Ser 
        675                 680                 685             


Ala Ser Gly Ser Thr Ser Ser Gln Gly Asp Gln Ser Asn Pro Ala Gln 
    690                 695                 700                 


Ser Pro Phe Ser Pro His Ala Ser Pro His Leu Ser Ser Ile Pro Gly 
705                 710                 715                 720 


Gly Pro Ser Pro Ser Pro Val Gly Ser Pro Val Gly Ser Asn Gln Ser 
                725                 730                 735     


Arg Ser Gly Pro Ile Ser Pro Ala Ser Ile Pro Gly Ser Gln Met Pro 
            740                 745                 750         


Pro Gln Pro Pro Gly Ser Gln Ser Glu Ser Ser Ser His Pro Ala Leu 
        755                 760                 765             


Ser Gln Ser Pro Met Pro Gln Glu Arg Gly Phe Met Ala Gly Thr Gln 
    770                 775                 780                 


Arg Asn Pro Gln Met Ala Gln Tyr Gly Pro Gln Gln Thr Gly Pro Ser 
785                 790                 795                 800 


Met Ser Pro His Pro Ser Pro Gly Gly Gln Met His Ala Gly Ile Ser 
                805                 810                 815     


Ser Phe Gln Gln Ser Asn Ser Ser Gly Thr Tyr Gly Pro Gln Met Ser 
            820                 825                 830         


Gln Tyr Gly Pro Gln Gly Asn Tyr Ser Arg Pro Pro Ala Tyr Ser Gly 
        835                 840                 845             


Val Pro Ser Ala Ser Tyr Ser Gly Pro Gly Pro Gly Met Gly Ile Ser 
    850                 855                 860                 


Ala Asn Asn Gln Met His Gly Gln Gly Pro Ser Gln Pro Cys Gly Ala 
865                 870                 875                 880 


Val Pro Leu Gly Arg Met Pro Ser Ala Gly Met Gln Asn Arg Pro Phe 
                885                 890                 895     


Pro Gly Asn Met Ser Ser Met Thr Pro Ser Ser Pro Gly Met Ser Gln 
            900                 905                 910         


Gln Gly Gly Pro Gly Met Gly Pro Pro Met Pro Thr Val Asn Arg Lys 
        915                 920                 925             


Ala Gln Glu Ala Ala Ala Ala Val Met Gln Ala Ala Ala Asn Ser Ala 
    930                 935                 940                 


Gln Ser Arg Gln Gly Ser Phe Pro Gly Met Asn Gln Ser Gly Leu Met 
945                 950                 955                 960 


Ala Ser Ser Ser Pro Tyr Ser Gln Pro Met Asn Asn Ser Ser Ser Leu 
                965                 970                 975     


Met Asn Thr Gln Ala Pro Pro Tyr Ser Met Ala Pro Ala Met Val Asn 
            980                 985                 990         


Ser Ser Ala Ala Ser Val Gly Leu  Ala Asp Met Met Ser  Pro Gly Glu 
        995                 1000                 1005             


Ser Lys  Leu Pro Leu Pro Leu  Lys Ala Asp Gly Lys  Glu Glu Gly 
    1010                 1015                 1020             


Thr Pro  Gln Pro Glu Ser Lys  Ser Lys Lys Ser Ser  Ser Ser Thr 
    1025                 1030                 1035             


Thr Thr  Gly Glu Lys Ile Thr  Lys Val Tyr Glu Leu  Gly Asn Glu 
    1040                 1045                 1050             


Pro Glu  Arg Lys Leu Trp Val  Asp Arg Tyr Leu Thr  Phe Met Glu 
    1055                 1060                 1065             


Glu Arg  Gly Ser Pro Val Ser  Ser Leu Pro Ala Val  Gly Lys Lys 
    1070                 1075                 1080             


Pro Leu  Asp Leu Phe Arg Leu  Tyr Val Cys Val Lys  Glu Ile Gly 
    1085                 1090                 1095             


Gly Leu  Ala Gln Val Asn Lys  Asn Lys Lys Trp Arg  Glu Leu Ala 
    1100                 1105                 1110             


Thr Asn  Leu Asn Val Gly Thr  Ser Ser Ser Ala Ala  Ser Ser Leu 
    1115                 1120                 1125             


Lys Lys  Gln Tyr Ile Gln Tyr  Leu Phe Ala Phe Glu  Cys Lys Ile 
    1130                 1135                 1140             


Glu Arg  Gly Glu Glu Pro Pro  Pro Glu Val Phe Ser  Thr Gly Asp 
    1145                 1150                 1155             


Thr Lys  Lys Gln Pro Lys Leu  Gln Pro Pro Ser Pro  Ala Asn Ser 
    1160                 1165                 1170             


Gly Ser  Leu Gln Gly Pro Gln  Thr Pro Gln Ser Thr  Gly Ser Asn 
    1175                 1180                 1185             


Ser Met  Ala Glu Val Pro Gly  Asp Leu Lys Pro Pro  Thr Pro Ala 
    1190                 1195                 1200             


Ser Thr  Pro His Gly Gln Met  Thr Pro Met Gln Gly  Gly Arg Ser 
    1205                 1210                 1215             


Ser Thr  Ile Ser Val His Asp  Pro Phe Ser Asp Val  Ser Asp Ser 
    1220                 1225                 1230             


Ser Phe  Pro Lys Arg Asn Ser  Met Thr Pro Asn Ala  Pro Tyr Gln 
    1235                 1240                 1245             


Gln Gly  Met Ser Met Pro Asp  Val Met Gly Arg Met  Pro Tyr Glu 
    1250                 1255                 1260             


Pro Asn  Lys Asp Pro Phe Gly  Gly Met Arg Lys Val  Pro Gly Ser 
    1265                 1270                 1275             


Ser Glu  Pro Phe Met Thr Gln  Gly Gln Met Pro Asn  Ser Ser Met 
    1280                 1285                 1290             


Gln Asp  Met Tyr Asn Gln Ser  Pro Ser Gly Ala Met  Ser Asn Leu 
    1295                 1300                 1305             


Gly Met  Gly Gln Arg Gln Gln  Phe Pro Tyr Gly Ala  Ser Tyr Asp 
    1310                 1315                 1320             


Arg Arg  His Glu Pro Tyr Gly  Gln Gln Tyr Pro Gly  Gln Gly Pro 
    1325                 1330                 1335             


Pro Ser  Gly Gln Pro Pro Tyr  Gly Gly His Gln Pro  Gly Leu Tyr 
    1340                 1345                 1350             


Pro Gln  Gln Pro Asn Tyr Lys  Arg His Met Asp Gly  Met Tyr Gly 
    1355                 1360                 1365             


Pro Pro  Ala Lys Arg His Glu  Gly Asp Met Tyr Asn  Met Gln Tyr 
    1370                 1375                 1380             


Ser Ser  Gln Gln Gln Glu Met  Tyr Asn Gln Tyr Gly  Gly Ser Tyr 
    1385                 1390                 1395             


Ser Gly  Pro Asp Arg Arg Pro  Ile Gln Gly Gln Tyr  Pro Tyr Pro 
    1400                 1405                 1410             


Tyr Ser  Arg Glu Arg Met Gln  Gly Pro Gly Gln Ile  Gln Thr His 
    1415                 1420                 1425             


Gly Ile  Pro Pro Gln Met Met  Gly Gly Pro Leu Gln  Ser Ser Ser 
    1430                 1435                 1440             


Ser Glu  Gly Pro Gln Gln Asn  Met Trp Ala Ala Arg  Asn Asp Met 
    1445                 1450                 1455             


Pro Tyr  Pro Tyr Gln Asn Arg  Gln Gly Pro Gly Gly  Pro Thr Gln 
    1460                 1465                 1470             


Ala Pro  Pro Tyr Pro Gly Met  Asn Arg Thr Asp Asp  Met Met Val 
    1475                 1480                 1485             


Pro Asp  Gln Arg Ile Asn His  Glu Ser Gln Trp Pro  Ser His Val 
    1490                 1495                 1500             


Ser Gln  Arg Gln Pro Tyr Met  Ser Ser Ser Ala Ser  Met Gln Pro 
    1505                 1510                 1515             


Ile Thr  Arg Pro Pro Gln Pro  Ser Tyr Gln Thr Pro  Pro Ser Leu 
    1520                 1525                 1530             


Pro Asn  His Ile Ser Arg Ala  Pro Ser Pro Ala Ser  Phe Gln Arg 
    1535                 1540                 1545             


Ser Leu  Glu Asn Arg Met Ser  Pro Ser Lys Ser Pro  Phe Leu Pro 
    1550                 1555                 1560             


Ser Met  Lys Met Gln Lys Val  Met Pro Thr Val Pro  Thr Ser Gln 
    1565                 1570                 1575             


Val Thr  Gly Pro Pro Pro Gln  Pro Pro Pro Ile Arg  Arg Glu Ile 
    1580                 1585                 1590             


Thr Phe  Pro Pro Gly Ser Val  Glu Ala Ser Gln Pro  Val Leu Lys 
    1595                 1600                 1605             


Gln Arg  Arg Lys Ile Thr Ser  Lys Asp Ile Val Thr  Pro Glu Ala 
    1610                 1615                 1620             


Trp Arg  Val Met Met Ser Leu  Lys Ser Gly Leu Leu  Ala Glu Ser 
    1625                 1630                 1635             


Thr Trp  Ala Leu Asp Thr Ile  Asn Ile Leu Leu Tyr  Asp Asp Ser 
    1640                 1645                 1650             


Thr Val  Ala Thr Phe Asn Leu  Ser Gln Leu Ser Gly  Phe Leu Glu 
    1655                 1660                 1665             


Leu Leu  Val Glu Tyr Phe Arg  Lys Cys Leu Ile Asp  Ile Phe Gly 
    1670                 1675                 1680             


Ile Leu  Met Glu Tyr Glu Val  Gly Asp Pro Ser Gln  Lys Ala Leu 
    1685                 1690                 1695             


Asp His  Asn Ala Ala Arg Lys  Asp Asp Ser Gln Ser  Leu Ala Asp 
    1700                 1705                 1710             


Asp Ser  Gly Lys Glu Glu Glu  Asp Ala Glu Cys Ile  Asp Asp Asp 
    1715                 1720                 1725             


Glu Glu  Asp Glu Glu Asp Glu  Glu Glu Asp Ser Glu  Lys Thr Glu 
    1730                 1735                 1740             


Ser Asp  Glu Lys Ser Ser Ile  Ala Leu Thr Ala Pro  Asp Ala Ala 
    1745                 1750                 1755             


Ala Asp  Pro Lys Glu Lys Pro  Lys Gln Ala Ser Lys  Phe Asp Lys 
    1760                 1765                 1770             


Leu Pro  Ile Lys Ile Val Lys  Lys Asn Asn Leu Phe  Val Val Asp 
    1775                 1780                 1785             


Arg Ser  Asp Lys Leu Gly Arg  Val Gln Glu Phe Asn  Ser Gly Leu 
    1790                 1795                 1800             


Leu His  Trp Gln Leu Gly Gly  Gly Asp Thr Thr Glu  His Ile Gln 
    1805                 1810                 1815             


Thr His  Phe Glu Ser Lys Met  Glu Ile Pro Pro Arg  Arg Arg Pro 
    1820                 1825                 1830             


Pro Pro  Pro Leu Ser Ser Ala  Gly Arg Lys Lys Glu  Gln Glu Gly 
    1835                 1840                 1845             


Lys Gly  Asp Ser Glu Glu Gln  Gln Glu Lys Ser Ile  Ile Ala Thr 
    1850                 1855                 1860             


Ile Asp  Asp Val Leu Ser Ala  Arg Pro Gly Ala Leu  Pro Glu Asp 
    1865                 1870                 1875             


Ala Asn  Pro Gly Pro Gln Thr  Glu Ser Ser Lys Phe  Pro Phe Gly 
    1880                 1885                 1890             


Ile Gln  Gln Ala Lys Ser His  Arg Asn Ile Lys Leu  Leu Glu Asp 
    1895                 1900                 1905             


Glu Pro  Arg Ser Arg Asp Glu  Thr Pro Leu Cys Thr  Ile Ala His 
    1910                 1915                 1920             


Trp Gln  Asp Ser Leu Ala Lys  Arg Cys Ile Cys Val  Ser Asn Ile 
    1925                 1930                 1935             


Val Arg  Ser Leu Ser Phe Val  Pro Gly Asn Asp Ala  Glu Met Ser 
    1940                 1945                 1950             


Lys His  Pro Gly Leu Val Leu  Ile Leu Gly Lys Leu  Ile Leu Leu 
    1955                 1960                 1965             


His His  Glu His Pro Glu Arg  Lys Arg Ala Pro Gln  Thr Tyr Glu 
    1970                 1975                 1980             


Lys Glu  Glu Asp Glu Asp Lys  Gly Val Ala Cys Ser  Lys Asp Glu 
    1985                 1990                 1995             


Trp Trp  Trp Asp Cys Leu Glu  Val Leu Arg Asp Asn  Thr Leu Val 
    2000                 2005                 2010             


Thr Leu  Ala Asn Ile Ser Gly  Gln Leu Asp Leu Ser  Ala Tyr Thr 
    2015                 2020                 2025             


Glu Ser  Ile Cys Leu Pro Ile  Leu Asp Gly Leu Leu  His Trp Met 
    2030                 2035                 2040             


Val Cys  Pro Ser Ala Glu Ala  Gln Asp Pro Phe Pro  Thr Val Gly 
    2045                 2050                 2055             


Pro Asn  Ser Val Leu Ser Pro  Gln Arg Leu Val Leu  Glu Thr Leu 
    2060                 2065                 2070             


Cys Lys  Leu Ser Ile Gln Asp  Asn Asn Val Asp Leu  Ile Leu Ala 
    2075                 2080                 2085             


Thr Pro  Pro Phe Ser Arg Gln  Glu Lys Phe Tyr Ala  Thr Leu Val 
    2090                 2095                 2100             


Arg Tyr  Val Gly Asp Arg Lys  Asn Pro Val Cys Arg  Glu Met Ser 
    2105                 2110                 2115             


Met Ala  Leu Leu Ser Asn Leu  Ala Gln Gly Asp Ala  Leu Ala Ala 
    2120                 2125                 2130             


Arg Ala  Ile Ala Val Gln Lys  Gly Ser Ile Gly Asn  Leu Ile Ser 
    2135                 2140                 2145             


Phe Leu  Glu Asp Gly Val Thr  Met Ala Gln Tyr Gln  Gln Ser Gln 
    2150                 2155                 2160             


His Asn  Leu Met His Met Gln  Pro Pro Pro Leu Glu  Pro Pro Ser 
    2165                 2170                 2175             


Val Asp  Met Met Cys Arg Ala  Ala Lys Ala Leu Leu  Ala Met Ala 
    2180                 2185                 2190             


Arg Val  Asp Glu Asn Arg Ser  Glu Phe Leu Leu His  Glu Gly Arg 
    2195                 2200                 2205             


Leu Leu  Asp Ile Ser Ile Ser  Ala Val Leu Asn Ser  Leu Val Ala 
    2210                 2215                 2220             


Ser Val  Ile Cys Asp Val Leu  Phe Gln Ile Gly Gln  Leu 
    2225                 2230                 2235     


<210>  3557
<211>  385
<212>  PRT
<213>  homo sapiens

<400>  3557

Met Ser Lys Pro Ala Gly Ser Thr Ser Arg Ile Leu Asp Ile Pro Cys 
1               5                   10                  15      


Lys Val Cys Gly Asp Arg Ser Ser Gly Lys His Tyr Gly Val Tyr Ala 
            20                  25                  30          


Cys Asp Gly Cys Ser Gly Phe Phe Lys Arg Ser Ile Arg Arg Asn Arg 
        35                  40                  45              


Thr Tyr Val Cys Lys Ser Gly Asn Gln Gly Gly Cys Pro Val Asp Lys 
    50                  55                  60                  


Thr His Arg Asn Gln Cys Arg Ala Cys Arg Leu Lys Lys Cys Leu Glu 
65                  70                  75                  80  


Val Asn Met Asn Lys Asp Ala Val Gln His Glu Arg Gly Pro Arg Thr 
                85                  90                  95      


Ser Thr Ile Arg Lys Gln Val Ala Leu Tyr Phe Arg Gly His Lys Glu 
            100                 105                 110         


Glu Asn Gly Ala Ala Ala His Phe Pro Ser Ala Ala Leu Pro Ala Pro 
        115                 120                 125             


Ala Phe Phe Thr Ala Val Thr Gln Leu Glu Pro His Gly Leu Glu Leu 
    130                 135                 140                 


Ala Ala Val Ser Thr Thr Pro Glu Arg Gln Thr Leu Val Ser Leu Ala 
145                 150                 155                 160 


Gln Pro Thr Pro Lys Tyr Pro His Glu Val Asn Gly Thr Pro Met Tyr 
                165                 170                 175     


Leu Tyr Glu Val Ala Thr Glu Ser Val Cys Glu Ser Ala Ala Arg Leu 
            180                 185                 190         


Leu Phe Met Ser Ile Lys Trp Ala Lys Ser Val Pro Ala Phe Ser Thr 
        195                 200                 205             


Leu Ser Leu Gln Asp Gln Leu Met Leu Leu Glu Asp Ala Trp Arg Glu 
    210                 215                 220                 


Leu Phe Val Leu Gly Ile Ala Gln Trp Ala Ile Pro Val Asp Ala Asn 
225                 230                 235                 240 


Thr Leu Leu Ala Val Ser Gly Met Asn Gly Asp Asn Thr Asp Ser Gln 
                245                 250                 255     


Lys Leu Asn Lys Ile Ile Ser Glu Ile Gln Ala Leu Gln Glu Val Val 
            260                 265                 270         


Ala Arg Phe Arg Gln Leu Arg Leu Asp Ala Thr Glu Phe Ala Cys Leu 
        275                 280                 285             


Lys Cys Ile Val Thr Phe Lys Ala Val Pro Thr His Ser Gly Ser Glu 
    290                 295                 300                 


Leu Arg Ser Phe Arg Asn Ala Ala Ala Ile Ala Ala Leu Gln Asp Glu 
305                 310                 315                 320 


Ala Gln Leu Thr Leu Asn Ser Tyr Ile His Thr Arg Tyr Pro Thr Gln 
                325                 330                 335     


Pro Cys Arg Phe Gly Lys Leu Leu Leu Leu Leu Pro Ala Leu Arg Ser 
            340                 345                 350         


Ile Ser Pro Ser Thr Ile Glu Glu Val Phe Phe Lys Lys Thr Ile Gly 
        355                 360                 365             


Asn Val Pro Ile Thr Arg Leu Leu Ser Asp Met Tyr Lys Ser Ser Asp 
    370                 375                 380                 


Ile 
385 


<210>  3558
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  3558

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  3559
<211>  119
<212>  PRT
<213>  homo sapiens

<400>  3559

Met Lys Ala Leu Ser Pro Val Arg Gly Cys Tyr Glu Ala Val Cys Cys 
1               5                   10                  15      


Leu Ser Glu Arg Ser Leu Ala Ile Ala Arg Gly Arg Gly Lys Gly Pro 
            20                  25                  30          


Ala Ala Glu Glu Pro Leu Ser Leu Leu Asp Asp Met Asn His Cys Tyr 
        35                  40                  45              


Ser Arg Leu Arg Glu Leu Val Pro Gly Val Pro Arg Gly Thr Gln Leu 
    50                  55                  60                  


Ser Gln Val Glu Ile Leu Gln Arg Val Ile Asp Tyr Ile Leu Asp Leu 
65                  70                  75                  80  


Gln Val Val Leu Ala Glu Pro Ala Pro Gly Pro Pro Asp Gly Pro His 
                85                  90                  95      


Leu Pro Ile Gln Thr Ala Glu Leu Thr Pro Glu Leu Val Ile Ser Asn 
            100                 105                 110         


Asp Lys Arg Ser Phe Cys His 
        115                 


<210>  3560
<211>  469
<212>  PRT
<213>  homo sapiens

<400>  3560

Met Asn Asp Phe Gly Ile Lys Asn Met Asp Gln Val Ala Pro Val Ala 
1               5                   10                  15      


Asn Ser Tyr Arg Gly Thr Leu Lys Arg Gln Pro Ala Phe Asp Thr Phe 
            20                  25                  30          


Asp Gly Ser Leu Phe Ala Val Phe Pro Ser Leu Asn Glu Glu Gln Thr 
        35                  40                  45              


Leu Gln Glu Val Pro Thr Gly Leu Asp Ser Ile Ser His Asp Ser Ala 
    50                  55                  60                  


Asn Cys Glu Leu Pro Leu Leu Thr Pro Cys Ser Lys Ala Val Met Ser 
65                  70                  75                  80  


Gln Ala Leu Lys Ala Thr Phe Ser Gly Phe Lys Lys Glu Gln Arg Arg 
                85                  90                  95      


Leu Gly Ile Pro Lys Asn Pro Trp Leu Trp Ser Glu Gln Gln Val Cys 
            100                 105                 110         


Gln Trp Leu Leu Trp Ala Thr Asn Glu Phe Ser Leu Val Asn Val Asn 
        115                 120                 125             


Leu Gln Arg Phe Gly Met Asn Gly Gln Met Leu Cys Asn Leu Gly Lys 
    130                 135                 140                 


Glu Arg Phe Leu Glu Leu Ala Pro Asp Phe Val Gly Asp Ile Leu Trp 
145                 150                 155                 160 


Glu His Leu Glu Gln Met Ile Lys Glu Asn Gln Glu Lys Thr Glu Asp 
                165                 170                 175     


Gln Tyr Glu Glu Asn Ser His Leu Thr Ser Val Pro His Trp Ile Asn 
            180                 185                 190         


Ser Asn Thr Leu Gly Phe Gly Thr Glu Gln Ala Pro Tyr Gly Met Gln 
        195                 200                 205             


Thr Gln Asn Tyr Pro Lys Gly Gly Leu Leu Asp Ser Met Cys Pro Ala 
    210                 215                 220                 


Ser Thr Pro Ser Val Leu Ser Ser Glu Gln Glu Phe Gln Met Phe Pro 
225                 230                 235                 240 


Lys Ser Arg Leu Ser Ser Val Ser Val Thr Tyr Cys Ser Val Ser Gln 
                245                 250                 255     


Asp Phe Pro Gly Ser Asn Leu Asn Leu Leu Thr Asn Asn Ser Gly Thr 
            260                 265                 270         


Pro Lys Asp His Asp Ser Pro Glu Asn Gly Ala Asp Ser Phe Glu Ser 
        275                 280                 285             


Ser Asp Ser Leu Leu Gln Ser Trp Asn Ser Gln Ser Ser Leu Leu Asp 
    290                 295                 300                 


Val Gln Arg Val Pro Ser Phe Glu Ser Phe Glu Asp Asp Cys Ser Gln 
305                 310                 315                 320 


Ser Leu Cys Leu Asn Lys Pro Thr Met Ser Phe Lys Asp Tyr Ile Gln 
                325                 330                 335     


Glu Arg Ser Asp Pro Val Glu Gln Gly Lys Pro Val Ile Pro Ala Ala 
            340                 345                 350         


Val Leu Ala Gly Phe Thr Gly Ser Gly Pro Ile Gln Leu Trp Gln Phe 
        355                 360                 365             


Leu Leu Glu Leu Leu Ser Asp Lys Ser Cys Gln Ser Phe Ile Ser Trp 
    370                 375                 380                 


Thr Gly Asp Gly Trp Glu Phe Lys Leu Ala Asp Pro Asp Glu Val Ala 
385                 390                 395                 400 


Arg Arg Trp Gly Lys Arg Lys Asn Lys Pro Lys Met Asn Tyr Glu Lys 
                405                 410                 415     


Leu Ser Arg Gly Leu Arg Tyr Tyr Tyr Asp Lys Asn Ile Ile His Lys 
            420                 425                 430         


Thr Ser Gly Lys Arg Tyr Val Tyr Arg Phe Val Cys Asp Leu Gln Asn 
        435                 440                 445             


Leu Leu Gly Phe Thr Pro Glu Glu Leu His Ala Ile Leu Gly Val Gln 
    450                 455                 460                 


Pro Asp Thr Glu Asp 
465                 


<210>  3561
<211>  477
<212>  PRT
<213>  homo sapiens

<400>  3561

Met Asp Gly Phe Tyr Asp Gln Gln Val Pro Tyr Met Val Thr Asn Ser 
1               5                   10                  15      


Gln Arg Gly Arg Asn Cys Asn Glu Lys Pro Thr Asn Val Arg Lys Arg 
            20                  25                  30          


Lys Phe Ile Asn Arg Asp Leu Ala His Asp Ser Glu Glu Leu Phe Gln 
        35                  40                  45              


Asp Leu Ser Gln Leu Gln Glu Thr Trp Leu Ala Glu Ala Gln Val Pro 
    50                  55                  60                  


Asp Asn Asp Glu Gln Phe Val Pro Asp Tyr Gln Ala Glu Ser Leu Ala 
65                  70                  75                  80  


Phe His Gly Leu Pro Leu Lys Ile Lys Lys Glu Pro His Ser Pro Cys 
                85                  90                  95      


Ser Glu Ile Ser Ser Ala Cys Ser Gln Glu Gln Pro Phe Lys Phe Ser 
            100                 105                 110         


Tyr Gly Glu Lys Cys Leu Tyr Asn Val Ser Ala Tyr Asp Gln Lys Pro 
        115                 120                 125             


Gln Val Gly Met Arg Pro Ser Asn Pro Pro Thr Pro Ser Ser Thr Pro 
    130                 135                 140                 


Val Ser Pro Leu His His Ala Ser Pro Asn Ser Thr His Thr Pro Lys 
145                 150                 155                 160 


Pro Asp Arg Ala Phe Pro Ala His Leu Pro Pro Ser Gln Ser Ile Pro 
                165                 170                 175     


Asp Ser Ser Tyr Pro Met Asp His Arg Phe Arg Arg Gln Leu Ser Glu 
            180                 185                 190         


Pro Cys Asn Ser Phe Pro Pro Leu Pro Thr Met Pro Arg Glu Gly Arg 
        195                 200                 205             


Pro Met Tyr Gln Arg Gln Met Ser Glu Pro Asn Ile Pro Phe Pro Pro 
    210                 215                 220                 


Gln Gly Phe Lys Gln Glu Tyr His Asp Pro Val Tyr Glu His Asn Thr 
225                 230                 235                 240 


Met Val Gly Ser Ala Ala Ser Gln Ser Phe Pro Pro Pro Leu Met Ile 
                245                 250                 255     


Lys Gln Glu Pro Arg Asp Phe Ala Tyr Asp Ser Glu Val Pro Ser Cys 
            260                 265                 270         


His Ser Ile Tyr Met Arg Gln Glu Gly Phe Leu Ala His Pro Ser Arg 
        275                 280                 285             


Thr Glu Gly Cys Met Phe Glu Lys Gly Pro Arg Gln Phe Tyr Asp Asp 
    290                 295                 300                 


Thr Cys Val Val Pro Glu Lys Phe Asp Gly Asp Ile Lys Gln Glu Pro 
305                 310                 315                 320 


Gly Met Tyr Arg Glu Gly Pro Thr Tyr Gln Arg Arg Gly Ser Leu Gln 
                325                 330                 335     


Leu Trp Gln Phe Leu Val Ala Leu Leu Asp Asp Pro Ser Asn Ser His 
            340                 345                 350         


Phe Ile Ala Trp Thr Gly Arg Gly Met Glu Phe Lys Leu Ile Glu Pro 
        355                 360                 365             


Glu Glu Val Ala Arg Arg Trp Gly Ile Gln Lys Asn Arg Pro Ala Met 
    370                 375                 380                 


Asn Tyr Asp Lys Leu Ser Arg Ser Leu Arg Tyr Tyr Tyr Glu Lys Gly 
385                 390                 395                 400 


Ile Met Gln Lys Val Ala Gly Glu Arg Tyr Val Tyr Lys Phe Val Cys 
                405                 410                 415     


Asp Pro Glu Ala Leu Phe Ser Met Ala Phe Pro Asp Asn Gln Arg Pro 
            420                 425                 430         


Leu Leu Lys Thr Asp Met Glu Arg His Ile Asn Glu Glu Asp Thr Val 
        435                 440                 445             


Pro Leu Ser His Phe Asp Glu Ser Met Ala Tyr Met Pro Glu Gly Gly 
    450                 455                 460                 


Cys Cys Asn Pro His Pro Tyr Asn Glu Gly Tyr Val Tyr 
465                 470                 475         


<210>  3562
<211>  782
<212>  PRT
<213>  homo sapiens

<400>  3562

Met Ser Ile Asn Leu Thr Val Asp Ile Tyr Ile Tyr Leu Leu Ser Asn 
1               5                   10                  15      


Ala Arg Ser Val Cys Gly Lys Gln Arg Ser Lys Gln Leu Tyr Phe Leu 
            20                  25                  30          


Phe Ser Pro Lys His Tyr Trp Arg Ile Ser His Ile Ser Leu Gln Arg 
        35                  40                  45              


Gly Phe His Thr Asn Ile Ile Arg Cys Lys Trp Thr Lys Ser Glu Ala 
    50                  55                  60                  


His Ser Cys Ser Lys His Cys Tyr Ser Pro Ser Asn His Gly Leu His 
65                  70                  75                  80  


Ile Gly Ile Leu Lys Leu Ser Thr Ser Ala Pro Lys Gly Leu Thr Lys 
                85                  90                  95      


Val Asn Ile Cys Met Ser Arg Ile Lys Ser Thr Leu Asn Ser Val Ser 
            100                 105                 110         


Lys Ala Val Phe Gly Asn Gln Asn Glu Met Ile Ser Arg Leu Ala Gln 
        115                 120                 125             


Phe Lys Pro Ser Ser Gln Ile Leu Arg Lys Val Ser Asp Ser Gly Trp 
    130                 135                 140                 


Leu Lys Gln Lys Asn Ile Lys Gln Ala Ile Lys Ser Leu Lys Lys Tyr 
145                 150                 155                 160 


Ser Asp Lys Ser Ala Glu Lys Ser Pro Phe Pro Glu Glu Lys Ser His 
                165                 170                 175     


Ile Ile Asp Lys Glu Glu Asp Ile Gly Lys Arg Ser Leu Phe His Tyr 
            180                 185                 190         


Thr Ser Ser Ile Thr Thr Lys Phe Gly Asp Ser Phe Tyr Phe Leu Ser 
        195                 200                 205             


Asn His Ile Asn Ser Tyr Phe Lys Arg Lys Glu Lys Met Ser Gln Gln 
    210                 215                 220                 


Lys Glu Asn Glu His Phe Arg Asp Lys Ser Glu Leu Glu Asp Lys Lys 
225                 230                 235                 240 


Val Glu Glu Gly Lys Leu Arg Ser Pro Asp Pro Gly Ile Leu Ala Tyr 
                245                 250                 255     


Lys Pro Gly Ser Glu Ser Val His Thr Val Asp Lys Pro Thr Ser Pro 
            260                 265                 270         


Ser Ala Ile Pro Asp Val Leu Gln Val Ser Thr Lys Gln Ser Ile Ala 
        275                 280                 285             


Asn Phe Leu Ser Arg Pro Thr Glu Gly Val Gln Ala Leu Val Gly Gly 
    290                 295                 300                 


Tyr Ile Gly Gly Leu Val Pro Lys Leu Lys Tyr Asp Ser Lys Ser Gln 
305                 310                 315                 320 


Ser Glu Glu Gln Glu Glu Pro Ala Lys Thr Asp Gln Ala Val Ser Lys 
                325                 330                 335     


Asp Arg Asn Ala Glu Glu Lys Lys Arg Leu Ser Leu Gln Arg Glu Lys 
            340                 345                 350         


Ile Ile Ala Arg Val Ser Ile Asp Asn Arg Thr Arg Ala Leu Val Gln 
        355                 360                 365             


Ala Leu Arg Arg Thr Thr Asp Pro Lys Leu Cys Ile Thr Arg Val Glu 
    370                 375                 380                 


Glu Leu Thr Phe His Leu Leu Glu Phe Pro Glu Gly Lys Gly Val Ala 
385                 390                 395                 400 


Val Lys Glu Arg Ile Ile Pro Tyr Leu Leu Arg Leu Arg Gln Ile Lys 
                405                 410                 415     


Asp Glu Thr Leu Gln Ala Ala Val Arg Glu Ile Leu Ala Leu Ile Gly 
            420                 425                 430         


Tyr Val Asp Pro Val Lys Gly Arg Gly Ile Arg Ile Leu Ser Ile Asp 
        435                 440                 445             


Gly Gly Gly Thr Arg Gly Val Val Ala Leu Gln Thr Leu Arg Lys Leu 
    450                 455                 460                 


Val Glu Leu Thr Gln Lys Pro Val His Gln Leu Phe Asp Tyr Ile Cys 
465                 470                 475                 480 


Gly Val Ser Thr Gly Ala Ile Leu Ala Phe Met Leu Gly Leu Phe His 
                485                 490                 495     


Met Pro Leu Asp Glu Cys Glu Glu Leu Tyr Arg Lys Leu Gly Ser Asp 
            500                 505                 510         


Val Phe Ser Gln Asn Val Ile Val Gly Thr Val Lys Met Ser Trp Ser 
        515                 520                 525             


His Ala Phe Tyr Asp Ser Gln Thr Trp Glu Asn Ile Leu Lys Asp Arg 
    530                 535                 540                 


Met Gly Ser Ala Leu Met Ile Glu Thr Ala Arg Asn Pro Thr Cys Pro 
545                 550                 555                 560 


Lys Val Ala Ala Val Ser Thr Ile Val Asn Arg Gly Ile Thr Pro Lys 
                565                 570                 575     


Ala Phe Val Phe Arg Asn Tyr Gly His Phe Pro Gly Ile Asn Ser His 
            580                 585                 590         


Tyr Leu Gly Gly Cys Gln Tyr Lys Met Trp Gln Ala Ile Arg Ala Ser 
        595                 600                 605             


Ser Ala Ala Pro Gly Tyr Phe Ala Glu Tyr Ala Leu Gly Asn Asp Leu 
    610                 615                 620                 


His Gln Asp Gly Gly Leu Leu Leu Asn Asn Pro Ser Ala Leu Ala Met 
625                 630                 635                 640 


His Glu Cys Lys Cys Leu Trp Pro Asp Val Pro Leu Glu Cys Ile Val 
                645                 650                 655     


Ser Leu Gly Thr Gly Arg Tyr Glu Ser Asp Val Arg Asn Thr Val Thr 
            660                 665                 670         


Tyr Thr Ser Leu Lys Thr Lys Leu Ser Asn Val Ile Asn Ser Ala Thr 
        675                 680                 685             


Asp Thr Glu Glu Val His Ile Met Leu Asp Gly Leu Leu Pro Pro Asp 
    690                 695                 700                 


Thr Tyr Phe Arg Phe Asn Pro Val Met Cys Glu Asn Ile Pro Leu Asp 
705                 710                 715                 720 


Glu Ser Arg Asn Glu Lys Leu Asp Gln Leu Gln Leu Glu Gly Leu Lys 
                725                 730                 735     


Tyr Ile Glu Arg Asn Glu Gln Lys Met Lys Lys Val Ala Lys Ile Leu 
            740                 745                 750         


Ser Gln Glu Lys Thr Thr Leu Gln Lys Ile Asn Asp Trp Ile Lys Leu 
        755                 760                 765             


Lys Thr Asp Met Tyr Glu Gly Leu Pro Phe Phe Ser Lys Leu 
    770                 775                 780         


<210>  3563
<211>  527
<212>  PRT
<213>  homo sapiens

<400>  3563

Met Ala Pro Glu Arg Leu Arg Ser Arg Ala Leu Ser Ala Phe Lys Leu 
1               5                   10                  15      


Arg Gly Leu Leu Leu Arg Gly Glu Ala Ile Lys Tyr Leu Thr Glu Ala 
            20                  25                  30          


Leu Gln Ser Ile Ser Glu Leu Glu Leu Glu Asp Lys Leu Glu Lys Ile 
        35                  40                  45              


Ile Asn Ala Val Glu Lys Gln Pro Leu Ser Ser Asn Met Ile Glu Arg 
    50                  55                  60                  


Ser Val Val Glu Ala Ala Val Gln Glu Cys Ser Gln Ser Val Asp Glu 
65                  70                  75                  80  


Thr Ile Glu His Val Phe Asn Ile Ile Gly Ala Phe Asp Ile Pro Arg 
                85                  90                  95      


Phe Val Tyr Asn Ser Glu Arg Lys Lys Phe Leu Pro Leu Leu Met Thr 
            100                 105                 110         


Asn His Pro Ala Pro Asn Leu Phe Gly Thr Pro Arg Asp Lys Ala Glu 
        115                 120                 125             


Met Phe Arg Glu Arg Tyr Thr Ile Leu His Gln Arg Thr His Arg His 
    130                 135                 140                 


Glu Leu Phe Thr Pro Pro Val Ile Gly Ser His Pro Asp Glu Ser Gly 
145                 150                 155                 160 


Ser Lys Phe Gln Leu Lys Thr Ile Glu Thr Leu Leu Gly Ser Thr Thr 
                165                 170                 175     


Lys Ile Gly Asp Ala Ile Val Leu Gly Met Ile Thr Gln Leu Lys Glu 
            180                 185                 190         


Gly Lys Phe Phe Leu Glu Asp Pro Thr Gly Thr Val Gln Leu Asp Leu 
        195                 200                 205             


Ser Lys Ala Gln Phe His Ser Gly Leu Tyr Thr Glu Ala Cys Phe Val 
    210                 215                 220                 


Leu Ala Glu Gly Trp Phe Glu Asp Gln Val Phe His Val Asn Ala Phe 
225                 230                 235                 240 


Gly Phe Pro Pro Thr Glu Pro Ser Ser Thr Thr Arg Ala Tyr Tyr Gly 
                245                 250                 255     


Asn Ile Asn Phe Phe Gly Gly Pro Ser Asn Thr Ser Val Lys Thr Ser 
            260                 265                 270         


Ala Lys Leu Lys Gln Leu Glu Glu Glu Asn Lys Asp Ala Met Phe Val 
        275                 280                 285             


Phe Leu Ser Asp Val Trp Leu Asp Gln Val Glu Val Leu Glu Lys Leu 
    290                 295                 300                 


Arg Ile Met Phe Ala Gly Tyr Ser Pro Ala Pro Pro Thr Cys Phe Ile 
305                 310                 315                 320 


Leu Cys Gly Asn Phe Ser Ser Ala Pro Tyr Gly Lys Asn Gln Val Gln 
                325                 330                 335     


Ala Leu Lys Asp Ser Leu Lys Thr Leu Ala Asp Ile Ile Cys Glu Tyr 
            340                 345                 350         


Pro Asp Ile His Gln Ser Ser Arg Phe Val Phe Val Pro Gly Pro Glu 
        355                 360                 365             


Asp Pro Gly Phe Gly Ser Ile Leu Pro Arg Pro Pro Leu Ala Glu Ser 
    370                 375                 380                 


Ile Thr Asn Glu Phe Arg Gln Arg Val Pro Phe Ser Val Phe Thr Thr 
385                 390                 395                 400 


Asn Pro Cys Arg Ile Gln Tyr Cys Thr Gln Glu Ile Thr Val Phe Arg 
                405                 410                 415     


Glu Asp Leu Val Asn Lys Met Cys Arg Asn Cys Val Arg Phe Pro Ser 
            420                 425                 430         


Ser Asn Leu Ala Ile Pro Asn His Phe Val Lys Thr Ile Leu Ser Gln 
        435                 440                 445             


Gly His Leu Thr Pro Leu Pro Leu Tyr Val Cys Pro Val Tyr Trp Ala 
    450                 455                 460                 


Tyr Asp Tyr Ala Leu Arg Val Tyr Pro Val Pro Asp Leu Leu Val Ile 
465                 470                 475                 480 


Ala Asp Lys Tyr Asp Pro Phe Thr Thr Thr Asn Thr Glu Cys Leu Cys 
                485                 490                 495     


Ile Asn Pro Gly Ser Phe Pro Arg Ser Gly Phe Ser Phe Lys Val Phe 
            500                 505                 510         


Tyr Pro Ser Asn Lys Thr Val Glu Asp Ser Lys Leu Gln Gly Phe 
        515                 520                 525         


<210>  3564
<211>  463
<212>  PRT
<213>  homo sapiens

<400>  3564

Met Val His Ser Ser Met Gly Ala Pro Glu Ile Arg Met Ser Lys Pro 
1               5                   10                  15      


Leu Glu Ala Glu Lys Gln Gly Leu Asp Ser Pro Ser Glu His Thr Asp 
            20                  25                  30          


Thr Glu Arg Asn Gly Pro Asp Thr Asn His Gln Asn Pro Gln Asn Lys 
        35                  40                  45              


Thr Ser Pro Phe Ser Val Ser Pro Thr Gly Pro Ser Thr Lys Ile Lys 
    50                  55                  60                  


Ala Glu Asp Pro Ser Gly Asp Ser Ala Pro Ala Ala Pro Leu Pro Pro 
65                  70                  75                  80  


Gln Pro Ala Gln Pro His Leu Pro Gln Ala Gln Leu Met Leu Thr Gly 
                85                  90                  95      


Ser Gln Leu Ala Gly Asp Ile Gln Gln Leu Leu Gln Leu Gln Gln Leu 
            100                 105                 110         


Val Leu Val Pro Gly His His Leu Gln Pro Pro Ala Gln Phe Leu Leu 
        115                 120                 125             


Pro Gln Ala Gln Gln Ser Gln Pro Gly Leu Leu Pro Thr Pro Asn Leu 
    130                 135                 140                 


Phe Gln Leu Pro Gln Gln Thr Gln Gly Ala Leu Leu Thr Ser Gln Pro 
145                 150                 155                 160 


Arg Ala Gly Leu Pro Thr Gln Pro Pro Lys Cys Leu Glu Pro Pro Ser 
                165                 170                 175     


His Pro Glu Glu Pro Ser Asp Leu Glu Glu Leu Glu Gln Phe Ala Arg 
            180                 185                 190         


Thr Phe Lys Gln Arg Arg Ile Lys Leu Gly Phe Thr Gln Gly Asp Val 
        195                 200                 205             


Gly Leu Ala Met Gly Lys Leu Tyr Gly Asn Asp Phe Ser Gln Thr Thr 
    210                 215                 220                 


Ile Ser Arg Phe Glu Ala Leu Asn Leu Ser Phe Lys Asn Met Cys Lys 
225                 230                 235                 240 


Leu Lys Pro Leu Leu Glu Lys Trp Leu Asn Asp Ala Glu Thr Met Ser 
                245                 250                 255     


Val Asp Ser Ser Leu Pro Ser Pro Asn Gln Leu Ser Ser Pro Ser Leu 
            260                 265                 270         


Gly Phe Asp Gly Leu Pro Gly Arg Arg Arg Lys Lys Arg Thr Ser Ile 
        275                 280                 285             


Glu Thr Asn Val Arg Phe Ala Leu Glu Lys Ser Phe Leu Ala Asn Gln 
    290                 295                 300                 


Lys Pro Thr Ser Glu Glu Ile Leu Leu Ile Ala Glu Gln Leu His Met 
305                 310                 315                 320 


Glu Lys Glu Val Ile Arg Val Trp Phe Cys Asn Arg Arg Gln Lys Glu 
                325                 330                 335     


Lys Arg Ile Asn Pro Cys Ser Ala Ala Pro Met Leu Pro Ser Pro Gly 
            340                 345                 350         


Lys Pro Ala Ser Tyr Ser Pro His Met Val Thr Pro Gln Gly Gly Ala 
        355                 360                 365             


Gly Thr Leu Pro Leu Ser Gln Ala Ser Ser Ser Leu Ser Thr Thr Val 
    370                 375                 380                 


Thr Thr Leu Ser Ser Ala Val Gly Thr Leu His Pro Ser Arg Thr Ala 
385                 390                 395                 400 


Gly Gly Gly Gly Gly Gly Gly Gly Ala Ala Pro Pro Leu Asn Ser Ile 
                405                 410                 415     


Pro Ser Val Thr Pro Pro Pro Pro Ala Thr Thr Asn Ser Thr Asn Pro 
            420                 425                 430         


Ser Pro Gln Gly Ser His Ser Ala Ile Gly Leu Ser Gly Leu Asn Pro 
        435                 440                 445             


Ser Thr Gly Pro Gly Leu Trp Trp Asn Pro Ala Pro Tyr Gln Pro 
    450                 455                 460             


<210>  3565
<211>  451
<212>  PRT
<213>  homo sapiens

<400>  3565

Met Ala Thr Thr Ala Gln Tyr Leu Pro Arg Gly Pro Gly Gly Gly Ala 
1               5                   10                  15      


Gly Gly Thr Gly Pro Leu Met His Pro Asp Ala Ala Ala Ala Ala Ala 
            20                  25                  30          


Ala Ala Ala Ala Ala Glu Arg Leu His Ala Gly Ala Ala Tyr Arg Glu 
        35                  40                  45              


Val Gln Lys Leu Met His His Glu Trp Leu Gly Ala Gly Ala Gly His 
    50                  55                  60                  


Pro Val Gly Leu Ala His Pro Gln Trp Leu Pro Thr Gly Gly Gly Gly 
65                  70                  75                  80  


Gly Gly Asp Trp Ala Gly Gly Pro His Leu Glu His Gly Lys Ala Gly 
                85                  90                  95      


Gly Gly Gly Thr Gly Arg Ala Asp Asp Gly Gly Gly Gly Gly Gly Phe 
            100                 105                 110         


His Ala Arg Leu Val His Gln Gly Ala Ala His Ala Gly Ala Ala Trp 
        115                 120                 125             


Ala Gln Gly Ser Thr Ala His His Leu Gly Pro Ala Met Ser Pro Ser 
    130                 135                 140                 


Pro Gly Ala Ser Gly Gly His Gln Pro Gln Pro Leu Gly Leu Tyr Ala 
145                 150                 155                 160 


Gln Ala Ala Tyr Pro Gly Gly Gly Gly Gly Gly Leu Ala Gly Met Leu 
                165                 170                 175     


Ala Ala Gly Gly Gly Gly Ala Gly Pro Gly Leu His His Ala Leu His 
            180                 185                 190         


Glu Asp Gly His Glu Ala Gln Leu Glu Pro Ser Pro Pro Pro His Leu 
        195                 200                 205             


Gly Ala His Gly His Ala His Gly His Ala His Ala Gly Gly Leu His 
    210                 215                 220                 


Ala Ala Ala Ala His Leu His Pro Gly Ala Gly Gly Gly Gly Ser Ser 
225                 230                 235                 240 


Val Gly Glu His Ser Asp Glu Asp Ala Pro Ser Ser Asp Asp Leu Glu 
                245                 250                 255     


Gln Phe Ala Lys Gln Phe Lys Gln Arg Arg Ile Lys Leu Gly Phe Thr 
            260                 265                 270         


Gln Ala Asp Val Gly Leu Ala Leu Gly Thr Leu Tyr Gly Asn Val Phe 
        275                 280                 285             


Ser Gln Thr Thr Ile Cys Arg Phe Glu Ala Leu Gln Leu Ser Phe Lys 
    290                 295                 300                 


Asn Met Cys Lys Leu Lys Pro Leu Leu Asn Lys Trp Leu Glu Glu Thr 
305                 310                 315                 320 


Asp Ser Ser Ser Gly Ser Pro Thr Asn Leu Asp Lys Ile Ala Ala Gln 
                325                 330                 335     


Gly Arg Lys Arg Lys Lys Arg Thr Ser Ile Glu Val Gly Val Lys Gly 
            340                 345                 350         


Ala Leu Glu Ser His Phe Leu Lys Cys Pro Lys Pro Ser Ala His Glu 
        355                 360                 365             


Ile Thr Gly Leu Ala Asp Ser Leu Gln Leu Glu Lys Glu Val Val Arg 
    370                 375                 380                 


Val Trp Phe Cys Asn Arg Arg Gln Lys Glu Lys Arg Met Thr Pro Ala 
385                 390                 395                 400 


Ala Gly Ala Gly His Pro Pro Met Asp Asp Val Tyr Ala Pro Gly Glu 
                405                 410                 415     


Leu Gly Pro Gly Gly Gly Gly Ala Ser Pro Pro Ser Ala Pro Pro Pro 
            420                 425                 430         


Pro Pro Pro Ala Ala Leu His His His His His His Thr Leu Pro Gly 
        435                 440                 445             


Ser Val Gln 
    450     


<210>  3566
<211>  713
<212>  PRT
<213>  homo sapiens

<400>  3566

Met Asp Glu Leu Ala Gly Gly Gly Gly Gly Gly Pro Gly Met Ala Ala 
1               5                   10                  15      


Pro Pro Arg Gln Gln Gln Gly Pro Gly Gly Asn Leu Gly Leu Ser Pro 
            20                  25                  30          


Gly Gly Asn Gly Ala Ala Gly Gly Gly Gly Pro Pro Ala Ser Glu Gly 
        35                  40                  45              


Ala Gly Pro Ala Ala Gly Pro Glu Leu Ser Arg Pro Gln Gln Tyr Thr 
    50                  55                  60                  


Ile Pro Gly Ile Leu His Tyr Ile Gln His Glu Trp Ala Arg Phe Glu 
65                  70                  75                  80  


Met Glu Arg Ala His Trp Glu Val Glu Arg Ala Glu Leu Gln Ala Arg 
                85                  90                  95      


Ile Ala Phe Leu Gln Gly Glu Arg Lys Gly Gln Glu Asn Leu Lys Lys 
            100                 105                 110         


Asp Leu Val Arg Arg Ile Lys Met Leu Glu Tyr Ala Leu Lys Gln Glu 
        115                 120                 125             


Arg Ala Lys Tyr His Lys Leu Lys Tyr Gly Thr Glu Leu Asn Gln Gly 
    130                 135                 140                 


Asp Leu Lys Met Pro Thr Phe Glu Ser Glu Glu Thr Lys Asp Thr Glu 
145                 150                 155                 160 


Ala Pro Thr Ala Pro Gln Asn Ser Gln Leu Thr Trp Lys Gln Gly Arg 
                165                 170                 175     


Gln Leu Leu Arg Gln Tyr Leu Gln Glu Val Gly Tyr Thr Asp Thr Ile 
            180                 185                 190         


Leu Asp Val Arg Ser Gln Arg Val Arg Ser Leu Leu Gly Leu Ser Asn 
        195                 200                 205             


Ser Glu Pro Asn Gly Ser Val Glu Thr Lys Asn Leu Glu Gln Ile Leu 
    210                 215                 220                 


Asn Gly Gly Glu Ser Pro Lys Gln Lys Gly Gln Glu Ile Lys Arg Ser 
225                 230                 235                 240 


Ser Gly Asp Val Leu Glu Thr Phe Asn Phe Leu Glu Asn Ala Asp Asp 
                245                 250                 255     


Ser Asp Glu Asp Glu Glu Asn Asp Met Ile Glu Gly Ile Pro Glu Gly 
            260                 265                 270         


Lys Asp Lys His Arg Met Asn Lys His Lys Ile Gly Asn Glu Gly Leu 
        275                 280                 285             


Ala Ala Asp Leu Thr Asp Asp Pro Asp Thr Glu Glu Ala Leu Lys Glu 
    290                 295                 300                 


Phe Asp Phe Leu Val Thr Ala Glu Asp Gly Glu Gly Ala Gly Glu Ala 
305                 310                 315                 320 


Arg Ser Ser Gly Asp Gly Thr Glu Trp Ala Glu Pro Ile Thr Phe Pro 
                325                 330                 335     


Ser Gly Gly Gly Lys Ser Phe Ile Met Gly Ser Asp Asp Val Leu Leu 
            340                 345                 350         


Ser Val Leu Gly Leu Gly Asp Leu Ala Asp Leu Thr Val Thr Asn Asp 
        355                 360                 365             


Ala Asp Tyr Ser Tyr Asp Leu Pro Ala Asn Lys Asp Ala Phe Arg Lys 
    370                 375                 380                 


Thr Trp Asn Pro Lys Tyr Thr Leu Arg Ser His Phe Asp Gly Val Arg 
385                 390                 395                 400 


Ala Leu Ala Phe His Pro Val Glu Pro Val Leu Val Thr Ala Ser Glu 
                405                 410                 415     


Asp His Thr Leu Lys Leu Trp Asn Leu Gln Lys Thr Val Pro Ala Lys 
            420                 425                 430         


Lys Ser Ala Ser Leu Asp Val Glu Pro Ile Tyr Thr Phe Arg Ala His 
        435                 440                 445             


Ile Gly Pro Val Leu Ser Leu Ala Ile Ser Ser Asn Gly Glu Gln Cys 
    450                 455                 460                 


Phe Ser Gly Gly Ile Asp Ala Thr Ile Gln Trp Trp Asn Met Pro Ser 
465                 470                 475                 480 


Pro Ser Val Asp Pro Tyr Asp Thr Tyr Glu Pro Asn Val Leu Ala Gly 
                485                 490                 495     


Thr Leu Val Gly His Thr Asp Ala Val Trp Gly Leu Ala Tyr Ser Gly 
            500                 505                 510         


Ile Lys Asn Gln Leu Leu Ser Cys Ser Ala Asp Gly Thr Val Arg Leu 
        515                 520                 525             


Trp Asn Pro Gln Glu Lys Leu Pro Cys Ile Cys Thr Tyr Asn Gly Asp 
    530                 535                 540                 


Lys Lys His Gly Ile Pro Thr Ser Val Asp Phe Ile Gly Cys Asp Pro 
545                 550                 555                 560 


Ala His Met Val Thr Ser Phe Asn Thr Gly Ser Ala Val Ile Tyr Asp 
                565                 570                 575     


Leu Glu Thr Ser Gln Ser Leu Val Ile Leu Ser Ser Gln Val Asp Ser 
            580                 585                 590         


Gly Leu Gln Ser Asn Asn His Ile Asn Arg Val Val Ser His Pro Thr 
        595                 600                 605             


Leu Pro Val Thr Ile Thr Ala His Glu Asp Arg His Ile Lys Phe Phe 
    610                 615                 620                 


Asp Asn Lys Thr Gly Lys Met Ile His Ser Met Val Ala His Leu Asp 
625                 630                 635                 640 


Ala Val Thr Ser Leu Ala Val Asp Pro Asn Gly Ile Tyr Leu Met Ser 
                645                 650                 655     


Gly Ser His Asp Cys Ser Ile Arg Leu Trp Asn Leu Asp Ser Lys Thr 
            660                 665                 670         


Cys Val Gln Glu Ile Thr Ala His Arg Lys Lys Leu Asp Glu Ser Ile 
        675                 680                 685             


Tyr Asp Val Ala Phe His Ser Ser Lys Ala Tyr Ile Ala Ser Ala Gly 
    690                 695                 700                 


Ala Asp Ala Leu Ala Lys Val Phe Val 
705                 710             


<210>  3567
<211>  797
<212>  PRT
<213>  homo sapiens

<400>  3567

Met Asp Glu Leu Ala Gly Gly Gly Gly Gly Gly Pro Gly Met Ala Ala 
1               5                   10                  15      


Pro Pro Arg Gln Gln Gln Gly Pro Gly Gly Asn Leu Gly Leu Ser Pro 
            20                  25                  30          


Gly Gly Asn Gly Ala Ala Gly Gly Gly Gly Pro Pro Ala Ser Glu Gly 
        35                  40                  45              


Ala Gly Pro Ala Ala Gly Pro Glu Leu Ser Arg Pro Gln Gln Tyr Thr 
    50                  55                  60                  


Ile Pro Gly Ile Leu His Tyr Ile Gln His Glu Trp Ala Arg Phe Glu 
65                  70                  75                  80  


Met Glu Arg Ala His Trp Glu Val Glu Arg Ala Glu Leu Gln Ala Arg 
                85                  90                  95      


Ile Ala Phe Leu Gln Gly Glu Arg Lys Gly Gln Glu Asn Leu Lys Lys 
            100                 105                 110         


Asp Leu Val Arg Arg Ile Lys Met Leu Glu Tyr Ala Leu Lys Gln Glu 
        115                 120                 125             


Arg Ala Lys Tyr His Lys Leu Lys Tyr Gly Thr Glu Leu Asn Gln Gly 
    130                 135                 140                 


Asp Leu Lys Met Pro Thr Phe Glu Ser Glu Glu Thr Lys Asp Thr Glu 
145                 150                 155                 160 


Ala Pro Thr Ala Pro Gln Asn Ser Gln Leu Thr Trp Lys Gln Gly Arg 
                165                 170                 175     


Gln Leu Leu Arg Gln Tyr Leu Gln Glu Val Gly Tyr Thr Asp Thr Ile 
            180                 185                 190         


Leu Asp Val Arg Ser Gln Arg Val Arg Ser Leu Leu Gly Leu Ser Asn 
        195                 200                 205             


Ser Glu Pro Asn Gly Ser Val Glu Thr Lys Asn Leu Glu Gln Ile Leu 
    210                 215                 220                 


Asn Gly Gly Glu Ser Pro Lys Gln Lys Gly Gln Glu Ile Lys Arg Ser 
225                 230                 235                 240 


Ser Gly Asp Val Leu Glu Thr Phe Asn Phe Leu Glu Asn Ala Asp Asp 
                245                 250                 255     


Ser Asp Glu Asp Glu Glu Asn Asp Met Ile Glu Gly Ile Pro Glu Gly 
            260                 265                 270         


Lys Asp Lys His Arg Met Asn Lys His Lys Ile Gly Asn Glu Gly Leu 
        275                 280                 285             


Ala Ala Asp Leu Thr Asp Asp Pro Asp Thr Glu Glu Ala Leu Lys Glu 
    290                 295                 300                 


Phe Asp Phe Leu Val Thr Ala Glu Asp Gly Glu Gly Ala Gly Glu Ala 
305                 310                 315                 320 


Arg Ser Ser Gly Asp Gly Thr Glu Trp Asp Lys Asp Asp Leu Ser Pro 
                325                 330                 335     


Thr Ala Glu Val Trp Asp Val Asp Gln Gly Leu Ile Ser Lys Leu Lys 
            340                 345                 350         


Glu Gln Tyr Lys Lys Glu Arg Lys Gly Lys Lys Gly Val Lys Arg Ala 
        355                 360                 365             


Asn Arg Thr Lys Leu Tyr Asp Met Ile Ala Asp Leu Gly Asp Asp Glu 
    370                 375                 380                 


Leu Pro His Ile Pro Ser Gly Ile Ile Asn Gln Ser Arg Ser Ala Ser 
385                 390                 395                 400 


Thr Arg Met Thr Asp His Glu Gly Ala Arg Ala Glu Glu Ala Glu Pro 
                405                 410                 415     


Ile Thr Phe Pro Ser Gly Gly Gly Lys Ser Phe Ile Met Gly Ser Asp 
            420                 425                 430         


Asp Val Leu Leu Ser Val Leu Gly Leu Gly Asp Leu Ala Asp Leu Thr 
        435                 440                 445             


Val Thr Asn Asp Ala Asp Tyr Ser Tyr Asp Leu Pro Ala Asn Lys Asp 
    450                 455                 460                 


Ala Phe Arg Lys Thr Trp Asn Pro Lys Tyr Thr Leu Arg Ser His Phe 
465                 470                 475                 480 


Asp Gly Val Arg Ala Leu Ala Phe His Pro Val Glu Pro Val Leu Val 
                485                 490                 495     


Thr Ala Ser Glu Asp His Thr Leu Lys Leu Trp Asn Leu Gln Lys Thr 
            500                 505                 510         


Val Pro Ala Lys Lys Ser Ala Ser Leu Asp Val Glu Pro Ile Tyr Thr 
        515                 520                 525             


Phe Arg Ala His Ile Gly Pro Val Leu Ser Leu Ala Ile Ser Ser Asn 
    530                 535                 540                 


Gly Glu Gln Cys Phe Ser Gly Gly Ile Asp Ala Thr Ile Gln Trp Trp 
545                 550                 555                 560 


Asn Met Pro Ser Pro Ser Val Asp Pro Tyr Asp Thr Tyr Glu Pro Asn 
                565                 570                 575     


Val Leu Ala Gly Thr Leu Val Gly His Thr Asp Ala Val Trp Gly Leu 
            580                 585                 590         


Ala Tyr Ser Gly Ile Lys Asn Gln Leu Leu Ser Cys Ser Ala Asp Gly 
        595                 600                 605             


Thr Val Arg Leu Trp Asn Pro Gln Glu Lys Leu Pro Cys Ile Cys Thr 
    610                 615                 620                 


Tyr Asn Gly Asp Lys Lys His Gly Ile Pro Thr Ser Val Asp Phe Ile 
625                 630                 635                 640 


Gly Cys Asp Pro Ala His Met Val Thr Ser Phe Asn Thr Gly Ser Ala 
                645                 650                 655     


Val Ile Tyr Asp Leu Glu Thr Ser Gln Ser Leu Val Ile Leu Ser Ser 
            660                 665                 670         


Gln Val Asp Ser Gly Leu Gln Ser Asn Asn His Ile Asn Arg Val Val 
        675                 680                 685             


Ser His Pro Thr Leu Pro Val Thr Ile Thr Ala His Glu Asp Arg His 
    690                 695                 700                 


Ile Lys Phe Phe Asp Asn Lys Thr Gly Lys Met Ile His Ser Met Val 
705                 710                 715                 720 


Ala His Leu Asp Ala Val Thr Ser Leu Ala Val Asp Pro Asn Gly Ile 
                725                 730                 735     


Tyr Leu Met Ser Gly Ser His Asp Cys Ser Ile Arg Leu Trp Asn Leu 
            740                 745                 750         


Asp Ser Lys Thr Cys Val Gln Glu Ile Thr Ala His Arg Lys Lys Leu 
        755                 760                 765             


Asp Glu Ser Ile Tyr Asp Val Ala Phe His Ser Ser Lys Ala Tyr Ile 
    770                 775                 780                 


Ala Ser Ala Gly Ala Asp Ala Leu Ala Lys Val Phe Val 
785                 790                 795         


<210>  3568
<211>  434
<212>  PRT
<213>  homo sapiens

<400>  3568

Met Gly Met Gly Arg Gly Ala Gly Arg Ser Ala Leu Gly Phe Trp Pro 
1               5                   10                  15      


Thr Leu Ala Phe Leu Leu Cys Ser Phe Pro Ala Ala Thr Ser Pro Cys 
            20                  25                  30          


Lys Ile Leu Lys Cys Asn Ser Glu Phe Trp Ser Ala Thr Ser Gly Ser 
        35                  40                  45              


His Ala Pro Ala Ser Asp Asp Thr Pro Glu Phe Cys Ala Ala Leu Arg 
    50                  55                  60                  


Ser Tyr Ala Leu Cys Thr Arg Arg Thr Ala Arg Thr Cys Arg Gly Asp 
65                  70                  75                  80  


Leu Ala Tyr His Ser Ala Val His Gly Ile Glu Asp Leu Met Ser Gln 
                85                  90                  95      


His Asn Cys Ser Lys Asp Gly Pro Thr Ser Gln Pro Arg Leu Arg Thr 
            100                 105                 110         


Leu Pro Pro Ala Gly Asp Ser Gln Glu Arg Ser Asp Ser Pro Glu Ile 
        115                 120                 125             


Cys His Tyr Glu Lys Ser Phe His Lys His Ser Ala Thr Pro Asn Tyr 
    130                 135                 140                 


Thr His Cys Gly Leu Phe Gly Asp Pro His Leu Arg Thr Phe Thr Asp 
145                 150                 155                 160 


Arg Phe Gln Thr Cys Lys Val Gln Gly Ala Trp Pro Leu Ile Asp Asn 
                165                 170                 175     


Asn Tyr Leu Asn Val Gln Val Thr Asn Thr Pro Val Leu Pro Gly Ser 
            180                 185                 190         


Ala Ala Thr Ala Thr Ser Lys Leu Thr Ile Ile Phe Lys Asn Phe Gln 
        195                 200                 205             


Glu Cys Val Asp Gln Lys Val Tyr Gln Ala Glu Met Asp Glu Leu Pro 
    210                 215                 220                 


Ala Ala Phe Val Asp Gly Ser Lys Asn Gly Gly Asp Lys His Gly Ala 
225                 230                 235                 240 


Asn Ser Leu Lys Ile Thr Glu Lys Val Ser Gly Gln His Val Glu Ile 
                245                 250                 255     


Gln Ala Lys Tyr Ile Gly Thr Thr Ile Val Val Arg Gln Val Gly Arg 
            260                 265                 270         


Tyr Leu Thr Phe Ala Val Arg Met Pro Glu Glu Val Val Asn Ala Val 
        275                 280                 285             


Glu Asp Trp Asp Ser Gln Gly Leu Tyr Leu Cys Leu Arg Gly Cys Pro 
    290                 295                 300                 


Leu Asn Gln Gln Ile Asp Phe Gln Ala Phe His Thr Asn Ala Glu Gly 
305                 310                 315                 320 


Thr Gly Ala Arg Arg Leu Ala Ala Ala Ser Pro Ala Pro Thr Ala Pro 
                325                 330                 335     


Glu Thr Phe Pro Tyr Glu Thr Ala Val Ala Lys Cys Lys Glu Lys Leu 
            340                 345                 350         


Pro Val Glu Asp Leu Tyr Tyr Gln Ala Cys Val Phe Asp Leu Leu Thr 
        355                 360                 365             


Thr Gly Asp Val Asn Phe Thr Leu Ala Ala Tyr Tyr Ala Leu Glu Asp 
    370                 375                 380                 


Val Lys Met Leu His Ser Asn Lys Asp Lys Leu His Leu Tyr Glu Arg 
385                 390                 395                 400 


Thr Arg Asp Leu Pro Gly Arg Ala Ala Ala Gly Leu Pro Leu Ala Pro 
                405                 410                 415     


Arg Pro Leu Leu Gly Ala Leu Val Pro Leu Leu Ala Leu Leu Pro Val 
            420                 425                 430         


Phe Cys 
        


<210>  3569
<211>  600
<212>  PRT
<213>  homo sapiens

<400>  3569

Met Val Leu Ile Leu Gly Arg Arg Leu Asn Arg Glu Asp Leu Gly Val 
1               5                   10                  15      


Arg Asp Ser Pro Ala Thr Lys Arg Lys Val Phe Glu Met Asp Pro Lys 
            20                  25                  30          


Ser Leu Thr Gly His Glu Phe Phe Asp Phe Ser Ser Gly Ser Ser His 
        35                  40                  45              


Ala Glu Asn Ile Leu Gln Ile Phe Asn Glu Phe Arg Asp Ser Arg Leu 
    50                  55                  60                  


Phe Thr Asp Val Ile Ile Cys Val Glu Gly Lys Glu Phe Pro Cys His 
65                  70                  75                  80  


Arg Ala Val Leu Ser Ala Cys Ser Ser Tyr Phe Arg Ala Met Phe Cys 
                85                  90                  95      


Asn Asp His Arg Glu Ser Arg Glu Met Leu Val Glu Ile Asn Gly Ile 
            100                 105                 110         


Leu Ala Glu Ala Met Glu Cys Phe Leu Gln Tyr Val Tyr Thr Gly Lys 
        115                 120                 125             


Val Lys Ile Thr Thr Glu Asn Val Gln Tyr Leu Phe Glu Thr Ser Ser 
    130                 135                 140                 


Leu Phe Gln Ile Ser Val Leu Arg Asp Ala Cys Ala Lys Phe Leu Glu 
145                 150                 155                 160 


Glu Gln Leu Asp Pro Cys Asn Cys Leu Gly Ile Gln Arg Phe Ala Asp 
                165                 170                 175     


Thr His Ser Leu Lys Thr Leu Phe Thr Lys Cys Lys Asn Phe Ala Leu 
            180                 185                 190         


Gln Thr Phe Glu Asp Val Ser Gln His Glu Glu Phe Leu Glu Leu Asp 
        195                 200                 205             


Lys Asp Glu Leu Ile Asp Tyr Ile Cys Ser Asp Glu Leu Val Ile Gly 
    210                 215                 220                 


Lys Glu Glu Met Val Phe Glu Ala Val Met Arg Trp Val Tyr Arg Ala 
225                 230                 235                 240 


Val Asp Leu Arg Arg Pro Leu Leu His Glu Leu Leu Thr His Val Arg 
                245                 250                 255     


Leu Pro Leu Leu His Pro Asn Tyr Phe Val Gln Thr Val Glu Val Asp 
            260                 265                 270         


Gln Leu Ile Gln Asn Ser Pro Glu Cys Tyr Gln Leu Leu His Glu Ala 
        275                 280                 285             


Arg Arg Tyr His Ile Leu Gly Asn Glu Met Met Ser Pro Arg Thr Arg 
    290                 295                 300                 


Pro Arg Arg Ser Thr Gly Tyr Ser Glu Val Ile Val Val Val Gly Gly 
305                 310                 315                 320 


Cys Glu Arg Val Gly Gly Phe Asn Leu Pro Tyr Thr Glu Cys Tyr Asp 
                325                 330                 335     


Pro Val Thr Gly Glu Trp Lys Ser Leu Ala Lys Leu Pro Glu Phe Thr 
            340                 345                 350         


Lys Ser Glu Tyr Ala Val Cys Ala Leu Arg Asn Asp Ile Leu Val Ser 
        355                 360                 365             


Gly Gly Arg Ile Asn Ser Arg Asp Val Trp Ile Tyr Asn Ser Gln Leu 
    370                 375                 380                 


Asn Ile Trp Ile Arg Val Ala Ser Leu Asn Lys Gly Arg Trp Arg His 
385                 390                 395                 400 


Lys Met Ala Val Leu Leu Gly Lys Val Tyr Val Val Gly Gly Tyr Asp 
                405                 410                 415     


Gly Gln Asn Arg Leu Ser Ser Val Glu Cys Tyr Asp Ser Phe Ser Asn 
            420                 425                 430         


Arg Trp Thr Glu Val Ala Pro Leu Lys Glu Ala Val Ser Ser Pro Ala 
        435                 440                 445             


Val Thr Ser Cys Val Gly Lys Leu Phe Val Ile Gly Gly Gly Pro Asp 
    450                 455                 460                 


Asp Asn Thr Cys Ser Asp Lys Val Gln Ser Tyr Asp Pro Glu Thr Asn 
465                 470                 475                 480 


Ser Trp Leu Leu Arg Ala Ala Ile Pro Ile Ala Lys Arg Cys Ile Thr 
                485                 490                 495     


Ala Val Ser Leu Asn Asn Leu Ile Tyr Val Ala Gly Gly Leu Thr Lys 
            500                 505                 510         


Ala Ile Tyr Cys Tyr Asp Pro Val Glu Asp Tyr Trp Met His Val Gln 
        515                 520                 525             


Asn Thr Phe Ser Arg Gln Glu Asn Cys Gly Met Ser Val Cys Asn Gly 
    530                 535                 540                 


Lys Ile Tyr Ile Leu Gly Gly Arg Arg Glu Asn Gly Glu Ala Thr Asp 
545                 550                 555                 560 


Thr Ile Leu Cys Tyr Asp Pro Ala Thr Ser Ile Ile Thr Gly Val Ala 
                565                 570                 575     


Ala Met Pro Arg Pro Val Ser Tyr His Gly Cys Val Thr Ile His Arg 
            580                 585                 590         


Tyr Asn Glu Lys Cys Phe Lys Leu 
        595                 600 


<210>  3570
<211>  583
<212>  PRT
<213>  homo sapiens

<400>  3570

Met Arg Gln Gly His Ala Pro Glu Glu Ser Glu Pro Gly Cys Glu Ala 
1               5                   10                  15      


Pro Cys Ala Gly Pro Cys His Ala Gln Arg Val Leu Gln Ala Leu Asn 
            20                  25                  30          


Ala Tyr Arg Arg Ser Gly Thr Leu Thr Asp Val Val Leu Arg Ala Gly 
        35                  40                  45              


Gly Arg Asp Phe Pro Cys His Arg Ala Ala Leu Ser Ala Gly Ser Ala 
    50                  55                  60                  


Tyr Phe Arg Ser Leu Phe Ala Ala Gly Arg Pro Glu Arg Gly Pro Ala 
65                  70                  75                  80  


Val Val Pro Val Val Pro Val Ala Pro Glu Ala Pro Gly Thr Ser Pro 
                85                  90                  95      


Ala Gly Ala Ala Ala Ala Leu Ala Val Val Leu Asp Tyr Val Tyr Gly 
            100                 105                 110         


Ala Gly Val Arg Leu Arg Ala Glu Asp Glu Ala Ala Ala Val Leu Ala 
        115                 120                 125             


Leu Ala Glu Arg Leu Gly Val Ala Gly Leu Arg Glu Ala Cys Val Arg 
    130                 135                 140                 


Phe Leu Glu Gly Arg Leu Arg Ala Ala Asn Ser Leu Ala Leu Arg Arg 
145                 150                 155                 160 


Val Ala Ala Ala Phe Ser Leu Ala Pro Leu Ala Glu Arg Cys Gly Arg 
                165                 170                 175     


Val Leu Arg Gln Ala Phe Ala Glu Val Ala Arg His Ala Asp Phe Leu 
            180                 185                 190         


Glu Leu Ala Pro Asp Glu Val Val Ala Leu Leu Ala Asp Pro Ala Leu 
        195                 200                 205             


Gly Val Ala Arg Glu Glu Ala Val Phe Glu Ala Ala Met Arg Trp Val 
    210                 215                 220                 


Arg His Asp Ala Pro Ala Arg Arg Gly Gln Leu Arg Arg Leu Leu Glu 
225                 230                 235                 240 


His Val Arg Leu Pro Leu Leu Ala Pro Ala Tyr Phe Leu Glu Lys Val 
                245                 250                 255     


Glu Ala Asp Glu Leu Leu Gln Ala Cys Gly Glu Cys Arg Pro Leu Leu 
            260                 265                 270         


Leu Glu Ala Arg Ala Cys Phe Ile Leu Gly Arg Glu Ala Gly Ala Leu 
        275                 280                 285             


Arg Thr Arg Pro Arg Arg Phe Met Asp Leu Ala Glu Val Ile Val Val 
    290                 295                 300                 


Ile Gly Gly Cys Asp Arg Lys Gly Leu Leu Lys Leu Pro Phe Ala Asp 
305                 310                 315                 320 


Ala Tyr His Pro Glu Ser Gln Arg Trp Thr Pro Leu Pro Ser Leu Pro 
                325                 330                 335     


Gly Tyr Thr Arg Ser Glu Phe Ala Ala Cys Ala Leu Arg Asn Asp Val 
            340                 345                 350         


Tyr Val Ser Gly Gly His Ile Asn Ser His Asp Val Trp Met Phe Ser 
        355                 360                 365             


Ser His Leu His Thr Trp Ile Lys Val Ala Ser Leu His Lys Gly Arg 
    370                 375                 380                 


Trp Arg His Lys Met Ala Val Val Gln Gly Gln Leu Phe Ala Val Gly 
385                 390                 395                 400 


Gly Phe Asp Gly Leu Arg Arg Leu His Ser Val Glu Arg Tyr Asp Pro 
                405                 410                 415     


Phe Ser Asn Thr Trp Ala Ala Ala Ala Pro Leu Pro Glu Ala Val Ser 
            420                 425                 430         


Ser Ala Ala Val Ala Ser Cys Ala Gly Lys Leu Phe Val Ile Gly Gly 
        435                 440                 445             


Ala Arg Gln Gly Gly Val Asn Thr Asp Lys Val Gln Cys Phe Asp Pro 
    450                 455                 460                 


Lys Glu Asp Arg Trp Ser Leu Arg Ser Pro Ala Pro Phe Ser Gln Arg 
465                 470                 475                 480 


Cys Leu Glu Ala Val Ser Leu Glu Asp Thr Ile Tyr Val Met Gly Gly 
                485                 490                 495     


Leu Met Ser Lys Ile Phe Thr Tyr Asp Pro Gly Thr Asp Val Trp Gly 
            500                 505                 510         


Glu Ala Ala Val Leu Pro Ser Pro Val Glu Ser Cys Gly Val Thr Val 
        515                 520                 525             


Cys Asp Gly Lys Val His Ile Leu Gly Gly Arg Asp Asp Arg Gly Glu 
    530                 535                 540                 


Ser Thr Asp Lys Val Phe Thr Phe Asp Pro Ser Ser Gly Gln Val Glu 
545                 550                 555                 560 


Val Gln Pro Ser Leu Gln Arg Cys Thr Ser Ser His Gly Cys Val Thr 
                565                 570                 575     


Ile Ile Gln Ser Leu Gly Arg 
            580             


<210>  3571
<211>  867
<212>  PRT
<213>  homo sapiens

<400>  3571

Met Gln Ala Glu Ala Ala Asp Trp Phe Ser Ser Met Pro Phe Gln Lys 
1               5                   10                  15      


His Val Tyr Tyr Pro Leu Ala Ser Gly Pro Glu Gly Pro Asp Val Ala 
            20                  25                  30          


Val Ala Ala Ala Ala Ala Gly Ala Ala Ser Met Ala Cys Ala Pro Pro 
        35                  40                  45              


Ser Ala Ala Ser Gly Pro Leu Pro Phe Phe Gln Phe Arg Pro Arg Leu 
    50                  55                  60                  


Glu Ser Val Asp Trp Arg Arg Leu Ser Ala Ile Asp Val Asp Lys Val 
65                  70                  75                  80  


Ala Gly Ala Val Asp Val Leu Thr Leu Gln Glu Asn Ile Met Asn Ile 
                85                  90                  95      


Thr Phe Cys Lys Leu Glu Asp Glu Lys Cys Pro His Cys Gln Ser Gly 
            100                 105                 110         


Val Asp Pro Val Leu Leu Lys Leu Ile Arg Leu Ala Gln Phe Thr Ile 
        115                 120                 125             


Glu Tyr Leu Leu His Ser Gln Glu Phe Leu Thr Ser Gln Leu His Thr 
    130                 135                 140                 


Leu Glu Glu Arg Leu Arg Leu Ser His Cys Asp Gly Glu Gln Ser Lys 
145                 150                 155                 160 


Lys Leu Leu Thr Lys Gln Ala Gly Glu Ile Lys Thr Leu Lys Glu Glu 
                165                 170                 175     


Cys Lys Arg Arg Lys Lys Met Ile Ser Thr Gln Gln Leu Met Ile Glu 
            180                 185                 190         


Ala Lys Ala Asn Tyr Tyr Gln Cys His Phe Cys Asp Lys Ala Phe Met 
        195                 200                 205             


Asn Gln Ala Phe Leu Gln Ser His Ile Gln Arg Arg His Thr Glu Glu 
    210                 215                 220                 


Asn Ser His Phe Glu Tyr Gln Lys Asn Ala Gln Ile Glu Lys Leu Arg 
225                 230                 235                 240 


Ser Glu Ile Val Val Leu Lys Glu Glu Leu Gln Leu Thr Arg Ser Glu 
                245                 250                 255     


Leu Glu Ala Ala His His Ala Ser Ala Val Arg Phe Ser Lys Glu Tyr 
            260                 265                 270         


Glu Met Gln Lys Thr Lys Glu Glu Asp Phe Leu Lys Leu Phe Asp Arg 
        275                 280                 285             


Trp Lys Glu Glu Glu Lys Glu Lys Leu Val Asp Glu Met Glu Lys Val 
    290                 295                 300                 


Lys Glu Met Phe Met Lys Glu Phe Lys Glu Leu Thr Ser Lys Asn Ser 
305                 310                 315                 320 


Ala Leu Glu Tyr Gln Leu Ser Glu Ile Gln Lys Ser Asn Met Gln Ile 
                325                 330                 335     


Lys Ser Asn Ile Gly Thr Leu Lys Asp Ala His Glu Phe Lys Glu Asp 
            340                 345                 350         


Arg Ser Pro Tyr Pro Gln Asp Phe His Asn Val Met Gln Leu Leu Asp 
        355                 360                 365             


Ser Gln Glu Ser Lys Trp Thr Ala Arg Val Gln Ala Ile His Gln Glu 
    370                 375                 380                 


His Lys Lys Glu Lys Gly Arg Leu Leu Ser His Ile Glu Lys Leu Arg 
385                 390                 395                 400 


Thr Ser Met Ile Asp Asp Leu Asn Ala Ser Asn Val Phe Tyr Lys Lys 
                405                 410                 415     


Arg Ile Glu Glu Leu Gly Gln Arg Leu Gln Glu Gln Asn Glu Leu Ile 
            420                 425                 430         


Ile Thr Gln Arg Gln Gln Ile Lys Asp Phe Thr Cys Asn Pro Leu Asn 
        435                 440                 445             


Ser Ile Ser Glu Pro Lys Gly Asn Pro Leu Ala Trp Gln Ala Phe Glu 
    450                 455                 460                 


Ser Gln Pro Ala Ala Pro Ala Val Pro Met Asn Ala Pro Ala Leu His 
465                 470                 475                 480 


Thr Leu Glu Thr Lys Ser Ser Leu Pro Met Val His Glu Gln Ala Phe 
                485                 490                 495     


Ser Ser His Ile Leu Glu Pro Ile Glu Glu Leu Ser Glu Glu Glu Lys 
            500                 505                 510         


Gly Arg Glu Asn Glu Gln Lys Leu Asn Asn Asn Lys Met His Leu Arg 
        515                 520                 525             


Lys Ala Leu Lys Ser Asn Ser Ser Leu Thr Lys Gly Leu Arg Thr Met 
    530                 535                 540                 


Val Glu Gln Asn Leu Met Glu Lys Leu Glu Thr Leu Gly Ile Asn Ala 
545                 550                 555                 560 


Asp Ile Arg Gly Ile Ser Ser Asp Gln Leu His Arg Val Leu Lys Ser 
                565                 570                 575     


Val Glu Ser Glu Arg His Lys Gln Glu Arg Glu Ile Pro Asn Phe His 
            580                 585                 590         


Gln Ile Arg Glu Phe Leu Glu His Gln Val Ser Cys Lys Ile Glu Glu 
        595                 600                 605             


Lys Ala Leu Leu Ser Ser Asp Gln Cys Ser Val Ser Gln Met Asp Thr 
    610                 615                 620                 


Leu Ser Thr Gly Glu Val Pro Lys Met Ile Gln Leu Pro Ser Lys Asn 
625                 630                 635                 640 


Arg Gln Leu Ile Arg Gln Lys Ala Val Ser Thr Asp Arg Thr Ser Val 
                645                 650                 655     


Pro Lys Ile Lys Lys Asn Val Met Glu Asp Pro Phe Pro Arg Lys Ser 
            660                 665                 670         


Ser Thr Ile Thr Thr Pro Pro Phe Ser Ser Glu Glu Glu Gln Glu Asp 
        675                 680                 685             


Asp Asp Leu Ile Arg Ala Tyr Ala Ser Pro Gly Pro Leu Pro Val Pro 
    690                 695                 700                 


Pro Pro Gln Asn Lys Gly Ser Phe Gly Lys Asn Thr Val Lys Ser Asp 
705                 710                 715                 720 


Ala Asp Gly Thr Glu Gly Ser Glu Ile Glu Asp Thr Asp Asp Ser Pro 
                725                 730                 735     


Lys Pro Ala Gly Val Ala Val Lys Thr Pro Thr Glu Lys Val Glu Lys 
            740                 745                 750         


Met Phe Pro His Arg Lys Asn Val Asn Lys Pro Val Gly Gly Thr Asn 
        755                 760                 765             


Val Pro Glu Met Phe Ile Lys Lys Glu Glu Leu Gln Glu Leu Lys Cys 
    770                 775                 780                 


Ala Asp Val Glu Asp Glu Asp Trp Asp Ile Ser Ser Leu Glu Glu Glu 
785                 790                 795                 800 


Ile Ser Leu Gly Lys Lys Ser Gly Lys Glu Gln Lys Glu Pro Pro Pro 
                805                 810                 815     


Ala Lys Asn Glu Pro His Phe Ala His Val Leu Asn Ala Trp Gly Ala 
            820                 825                 830         


Phe Asn Pro Lys Gly Pro Lys Gly Glu Gly Leu Gln Glu Asn Glu Ser 
        835                 840                 845             


Ser Thr Leu Lys Ser Ser Leu Val Thr Val Thr Asp Trp Ser Asp Thr 
    850                 855                 860                 


Ser Asp Val 
865         


<210>  3572
<211>  550
<212>  PRT
<213>  homo sapiens

<400>  3572

Met Val Pro Lys Ala Asp Ser Gly Ala Phe Leu Leu Leu Phe Leu Leu 
1               5                   10                  15      


Val Leu Thr Val Thr Glu Pro Leu Arg Pro Glu Leu Arg Cys Asn Pro 
            20                  25                  30          


Gly Gln Phe Ala Cys Arg Ser Gly Thr Ile Gln Cys Ile Pro Leu Pro 
        35                  40                  45              


Trp Gln Cys Asp Gly Trp Ala Thr Cys Glu Asp Glu Ser Asp Glu Ala 
    50                  55                  60                  


Asn Cys Pro Glu Val Thr Gly Glu Val Arg Pro His His Gly Lys Glu 
65                  70                  75                  80  


Ala Val Asp Pro Arg Gln Gly Arg Ala Arg Gly Gly Asp Pro Ser His 
                85                  90                  95      


Phe His Ala Val Asn Val Ala Gln Pro Val Arg Phe Ser Ser Phe Leu 
            100                 105                 110         


Gly Lys Cys Pro Thr Gly Trp His His Tyr Glu Gly Thr Ala Ser Cys 
        115                 120                 125             


Tyr Arg Val Tyr Leu Ser Gly Glu Asn Tyr Trp Asp Ala Ala Gln Thr 
    130                 135                 140                 


Cys Gln Arg Leu Asn Gly Ser Leu Ala Thr Phe Ser Thr Asp Gln Glu 
145                 150                 155                 160 


Leu Arg Phe Val Leu Ala Gln Glu Trp Asp Gln Pro Glu Arg Ser Phe 
                165                 170                 175     


Gly Trp Lys Asp Gln Arg Lys Leu Trp Val Gly Tyr Gln Tyr Val Ile 
            180                 185                 190         


Thr Gly Arg Asn Arg Ser Leu Glu Gly Arg Trp Glu Val Ala Phe Lys 
        195                 200                 205             


Gly Ser Ser Glu Val Phe Leu Pro Pro Asp Pro Ile Phe Ala Ser Ala 
    210                 215                 220                 


Met Ser Glu Asn Asp Asn Val Phe Cys Ala Gln Leu Gln Cys Phe His 
225                 230                 235                 240 


Phe Pro Thr Leu Arg His His Asp Leu His Ser Trp His Ala Glu Ser 
                245                 250                 255     


Cys Tyr Glu Lys Ser Ser Phe Leu Cys Lys Arg Ser Gln Thr Cys Val 
            260                 265                 270         


Asp Ile Lys Asp Asn Val Val Asp Glu Gly Phe Tyr Phe Thr Pro Lys 
        275                 280                 285             


Gly Asp Asp Pro Cys Leu Ser Cys Thr Cys His Gly Gly Glu Pro Glu 
    290                 295                 300                 


Met Cys Val Ala Ala Leu Cys Glu Arg Pro Gln Gly Cys Gln Gln Tyr 
305                 310                 315                 320 


Arg Lys Asp Pro Lys Glu Cys Cys Lys Phe Met Cys Leu Asp Pro Asp 
                325                 330                 335     


Gly Asn Ser Leu Phe Asp Ser Met Ala Ser Gly Met Arg Leu Val Val 
            340                 345                 350         


Ser Cys Ile Ser Ser Phe Leu Ile Leu Ser Leu Leu Leu Phe Met Val 
        355                 360                 365             


His Arg Leu Arg Gln Arg Arg Arg Glu Arg Ile Glu Ser Leu Ile Gly 
    370                 375                 380                 


Ala Asn Leu His His Phe Asn Leu Gly Arg Arg Ile Pro Gly Phe Asp 
385                 390                 395                 400 


Tyr Gly Pro Asp Gly Phe Gly Thr Gly Leu Thr Pro Leu His Leu Ser 
                405                 410                 415     


Asp Asp Gly Glu Gly Gly Thr Phe His Phe His Asp Pro Pro Pro Pro 
            420                 425                 430         


Tyr Thr Ala Tyr Lys Tyr Pro Asp Ile Gly Gln Pro Asp Asp Pro Pro 
        435                 440                 445             


Pro Pro Tyr Glu Ala Ser Ile His Pro Asp Ser Val Phe Tyr Asp Pro 
    450                 455                 460                 


Ala Asp Asp Asp Ala Phe Glu Pro Val Glu Val Ser Leu Pro Ala Pro 
465                 470                 475                 480 


Gly Asp Gly Gly Ser Glu Gly Ala Leu Leu Arg Arg Leu Glu Gln Pro 
                485                 490                 495     


Leu Pro Thr Ala Gly Ala Ser Leu Ala Asp Leu Glu Asp Ser Ala Asp 
            500                 505                 510         


Ser Ser Ser Ala Leu Leu Val Pro Pro Asp Pro Ala Gln Ser Gly Ser 
        515                 520                 525             


Thr Pro Ala Ala Glu Ala Leu Pro Gly Gly Gly Arg His Ser Arg Ser 
    530                 535                 540                 


Ser Leu Asn Thr Val Val 
545                 550 


<210>  3573
<211>  2485
<212>  PRT
<213>  homo sapiens

<400>  3573

Met His Val Ser Leu Ala Glu Ala Leu Glu Val Arg Gly Gly Pro Leu 
1               5                   10                  15      


Gln Glu Glu Glu Ile Trp Ala Val Leu Asn Gln Ser Ala Glu Ser Leu 
            20                  25                  30          


Gln Glu Leu Phe Arg Lys Val Ser Leu Ala Asp Pro Ala Ala Leu Gly 
        35                  40                  45              


Phe Ile Ile Ser Pro Trp Ser Leu Leu Leu Leu Pro Ser Gly Ser Val 
    50                  55                  60                  


Ser Phe Thr Asp Glu Asn Ile Ser Asn Gln Asp Leu Arg Ala Phe Thr 
65                  70                  75                  80  


Ala Pro Glu Val Leu Gln Asn Gln Ser Leu Thr Ser Leu Ser Asp Val 
                85                  90                  95      


Glu Lys Ile His Ile Tyr Ser Leu Gly Met Thr Leu Tyr Trp Gly Ala 
            100                 105                 110         


Asp Tyr Glu Val Pro Gln Ser Gln Pro Ile Lys Leu Gly Asp His Leu 
        115                 120                 125             


Asn Ser Ile Leu Leu Gly Met Cys Glu Asp Val Ile Tyr Ala Arg Val 
    130                 135                 140                 


Ser Val Arg Thr Val Leu Asp Ala Cys Ser Ala His Ile Arg Asn Ser 
145                 150                 155                 160 


Asn Cys Ala Pro Ser Phe Ser Tyr Val Lys His Leu Val Lys Leu Val 
                165                 170                 175     


Leu Gly Asn Leu Ser Gly Thr Asp Gln Leu Ser Cys Asn Ser Glu Gln 
            180                 185                 190         


Lys Pro Asp Arg Ser Gln Ala Ile Arg Asp Arg Leu Arg Gly Lys Gly 
        195                 200                 205             


Leu Pro Thr Gly Arg Ser Ser Thr Ser Asp Val Leu Asp Ile Gln Lys 
    210                 215                 220                 


Pro Pro Leu Ser His Gln Thr Phe Leu Asn Lys Gly Leu Ser Lys Ser 
225                 230                 235                 240 


Met Gly Phe Leu Ser Ile Lys Asp Thr Gln Asp Glu Asn Tyr Phe Lys 
                245                 250                 255     


Asp Ile Leu Ser Asp Asn Ser Gly Arg Glu Asp Ser Glu Asn Thr Phe 
            260                 265                 270         


Ser Pro Tyr Gln Phe Lys Thr Ser Gly Pro Glu Lys Lys Pro Ile Pro 
        275                 280                 285             


Gly Ile Asp Val Leu Ser Lys Lys Lys Ile Trp Ala Ser Ser Met Asp 
    290                 295                 300                 


Leu Leu Cys Thr Ala Asp Arg Asp Phe Ser Ser Gly Glu Thr Ala Thr 
305                 310                 315                 320 


Tyr Arg Arg Cys His Pro Glu Ala Val Thr Val Arg Thr Ser Thr Thr 
                325                 330                 335     


Pro Arg Lys Lys Glu Ala Arg Tyr Ser Asp Gly Ser Ile Ala Leu Asp 
            340                 345                 350         


Ile Phe Gly Pro Gln Lys Met Asp Pro Ile Tyr His Thr Arg Glu Leu 
        355                 360                 365             


Pro Thr Ser Ser Ala Ile Ser Ser Ala Leu Asp Arg Ile Arg Glu Arg 
    370                 375                 380                 


Gln Lys Lys Leu Gln Val Leu Arg Glu Ala Met Asn Val Glu Glu Pro 
385                 390                 395                 400 


Val Arg Arg Tyr Lys Thr Tyr His Gly Asp Val Phe Ser Thr Ser Ser 
                405                 410                 415     


Glu Ser Pro Ser Ile Ile Ser Ser Glu Ser Asp Phe Arg Gln Val Arg 
            420                 425                 430         


Arg Ser Glu Ala Ser Lys Arg Phe Glu Ser Ser Ser Gly Leu Pro Gly 
        435                 440                 445             


Val Asp Glu Thr Leu Ser Gln Gly Gln Ser Gln Arg Pro Ser Arg Gln 
    450                 455                 460                 


Tyr Glu Thr Pro Phe Glu Gly Asn Leu Ile Asn Gln Glu Ile Met Leu 
465                 470                 475                 480 


Lys Arg Gln Glu Glu Glu Leu Met Gln Leu Gln Ala Lys Met Ala Leu 
                485                 490                 495     


Arg Gln Ser Arg Leu Ser Leu Tyr Pro Gly Asp Thr Ile Lys Ala Ser 
            500                 505                 510         


Met Leu Asp Ile Thr Arg Asp Pro Leu Arg Glu Ile Ala Leu Glu Thr 
        515                 520                 525             


Ala Met Thr Gln Arg Lys Leu Arg Asn Phe Phe Gly Pro Glu Phe Val 
    530                 535                 540                 


Lys Met Thr Ile Glu Pro Phe Ile Ser Leu Asp Leu Pro Arg Ser Ile 
545                 550                 555                 560 


Leu Thr Lys Lys Gly Lys Asn Glu Asp Asn Arg Arg Lys Val Asn Ile 
                565                 570                 575     


Met Leu Leu Asn Gly Gln Arg Leu Glu Leu Thr Cys Asp Thr Lys Thr 
            580                 585                 590         


Ile Cys Lys Asp Val Phe Asp Met Val Val Ala His Ile Gly Leu Val 
        595                 600                 605             


Glu His His Leu Phe Ala Leu Ala Thr Leu Lys Asp Asn Glu Tyr Phe 
    610                 615                 620                 


Phe Val Asp Pro Asp Leu Lys Leu Thr Lys Val Ala Pro Glu Gly Trp 
625                 630                 635                 640 


Lys Glu Glu Pro Lys Lys Lys Thr Lys Ala Thr Val Asn Phe Thr Leu 
                645                 650                 655     


Phe Phe Arg Ile Lys Phe Phe Met Asp Asp Val Ser Leu Ile Gln His 
            660                 665                 670         


Thr Leu Thr Cys His Gln Tyr Tyr Leu Gln Leu Arg Lys Asp Ile Leu 
        675                 680                 685             


Glu Glu Arg Met His Cys Asp Asp Glu Thr Ser Leu Leu Leu Ala Ser 
    690                 695                 700                 


Leu Ala Leu Gln Ala Glu Tyr Gly Asp Tyr Gln Pro Glu Val His Gly 
705                 710                 715                 720 


Val Ser Tyr Phe Arg Met Glu His Tyr Leu Pro Ala Arg Val Met Glu 
                725                 730                 735     


Lys Leu Asp Leu Ser Tyr Ile Lys Glu Glu Leu Pro Lys Leu His Asn 
            740                 745                 750         


Thr Tyr Val Gly Ala Ser Glu Lys Glu Thr Glu Leu Glu Phe Leu Lys 
        755                 760                 765             


Val Cys Gln Arg Leu Thr Glu Tyr Gly Val His Phe His Arg Val His 
    770                 775                 780                 


Pro Glu Lys Lys Ser Gln Thr Gly Ile Leu Leu Gly Val Cys Ser Lys 
785                 790                 795                 800 


Gly Val Leu Val Phe Glu Val His Asn Gly Val Arg Thr Leu Val Leu 
                805                 810                 815     


Arg Phe Pro Trp Arg Glu Thr Lys Lys Ile Ser Phe Ser Lys Lys Lys 
            820                 825                 830         


Ile Thr Leu Gln Asn Thr Ser Asp Gly Ile Lys His Gly Phe Gln Thr 
        835                 840                 845             


Asp Asn Ser Lys Ile Cys Gln Tyr Leu Leu His Leu Cys Ser Tyr Gln 
    850                 855                 860                 


His Lys Phe Gln Leu Gln Met Arg Ala Arg Gln Ser Asn Gln Asp Ala 
865                 870                 875                 880 


Gln Asp Ile Glu Arg Ala Ser Phe Arg Ser Leu Asn Leu Gln Ala Glu 
                885                 890                 895     


Ser Val Arg Gly Phe Asn Met Gly Arg Ala Ile Ser Thr Gly Ser Leu 
            900                 905                 910         


Ala Ser Ser Thr Leu Asn Lys Leu Ala Val Arg Pro Leu Ser Val Gln 
        915                 920                 925             


Ala Glu Ile Leu Lys Arg Leu Ser Cys Ser Glu Leu Ser Leu Tyr Gln 
    930                 935                 940                 


Pro Leu Gln Asn Ser Ser Lys Glu Lys Asn Asp Lys Ala Ser Trp Glu 
945                 950                 955                 960 


Glu Lys Pro Arg Glu Met Ser Lys Ser Tyr His Asp Leu Ser Gln Ala 
                965                 970                 975     


Ser Leu Tyr Pro His Arg Lys Asn Val Ile Val Asn Met Glu Pro Pro 
            980                 985                 990         


Pro Gln Thr Val Ala Glu Leu Val  Gly Lys Pro Ser His  Gln Met Ser 
        995                 1000                 1005             


Arg Ser  Asp Ala Glu Ser Leu  Ala Gly Val Thr Lys  Leu Asn Asn 
    1010                 1015                 1020             


Ser Lys  Ser Val Ala Ser Leu  Asn Arg Ser Pro Glu  Arg Arg Lys 
    1025                 1030                 1035             


His Glu  Ser Asp Ser Ser Ser  Ile Glu Asp Pro Gly  Gln Ala Tyr 
    1040                 1045                 1050             


Val Leu  Gly Met Thr Met His  Ser Ser Gly Asn Ser  Ser Ser Gln 
    1055                 1060                 1065             


Val Pro  Leu Lys Glu Asn Asp  Val Leu His Lys Arg  Trp Ser Ile 
    1070                 1075                 1080             


Val Ser  Ser Pro Glu Arg Glu  Ile Thr Leu Val Asn  Leu Lys Lys 
    1085                 1090                 1095             


Asp Ala  Lys Tyr Gly Leu Gly  Phe Gln Ile Ile Gly  Gly Glu Lys 
    1100                 1105                 1110             


Met Gly  Arg Leu Asp Leu Gly  Ile Phe Ile Ser Ser  Val Ala Pro 
    1115                 1120                 1125             


Gly Gly  Pro Ala Asp Leu Asp  Gly Cys Leu Lys Pro  Gly Asp Arg 
    1130                 1135                 1140             


Leu Ile  Ser Val Asn Ser Val  Ser Leu Glu Gly Val  Ser His His 
    1145                 1150                 1155             


Ala Ala  Ile Glu Ile Leu Gln  Asn Ala Pro Glu Asp  Val Thr Leu 
    1160                 1165                 1170             


Val Ile  Ser Gln Pro Lys Glu  Lys Ile Ser Lys Val  Pro Ser Thr 
    1175                 1180                 1185             


Pro Val  His Leu Thr Asn Glu  Met Lys Asn Tyr Met  Lys Lys Ser 
    1190                 1195                 1200             


Ser Tyr  Met Gln Asp Ser Ala  Ile Asp Ser Ser Ser  Lys Asp His 
    1205                 1210                 1215             


His Trp  Ser Arg Gly Thr Leu  Arg His Ile Ser Glu  Asn Ser Phe 
    1220                 1225                 1230             


Gly Pro  Ser Gly Gly Leu Arg  Glu Gly Ser Leu Ser  Ser Gln Asp 
    1235                 1240                 1245             


Ser Arg  Thr Glu Ser Ala Ser  Leu Ser Gln Ser Gln  Val Asn Gly 
    1250                 1255                 1260             


Phe Phe  Ala Ser His Leu Gly  Asp Gln Thr Trp Gln  Glu Ser Gln 
    1265                 1270                 1275             


His Gly  Ser Pro Ser Pro Ser  Val Ile Ser Lys Ala  Thr Glu Lys 
    1280                 1285                 1290             


Glu Thr  Phe Thr Asp Ser Asn  Gln Ser Lys Thr Lys  Lys Pro Gly 
    1295                 1300                 1305             


Ile Ser  Asp Val Thr Asp Tyr  Ser Asp Arg Gly Asp  Ser Asp Met 
    1310                 1315                 1320             


Asp Glu  Ala Thr Tyr Ser Ser  Ser Gln Asp His Gln  Thr Pro Lys 
    1325                 1330                 1335             


Gln Glu  Ser Ser Ser Ser Val  Asn Thr Ser Asn Lys  Met Asn Phe 
    1340                 1345                 1350             


Lys Thr  Phe Ser Ser Ser Pro  Pro Lys Pro Gly Asp  Ile Phe Glu 
    1355                 1360                 1365             


Val Glu  Leu Ala Lys Asn Asp  Asn Ser Leu Gly Ile  Ser Val Thr 
    1370                 1375                 1380             


Gly Gly  Val Asn Thr Ser Val  Arg His Gly Gly Ile  Tyr Val Lys 
    1385                 1390                 1395             


Ala Val  Ile Pro Gln Gly Ala  Ala Glu Ser Asp Gly  Arg Ile His 
    1400                 1405                 1410             


Lys Gly  Asp Arg Val Leu Ala  Val Asn Gly Val Ser  Leu Glu Gly 
    1415                 1420                 1425             


Ala Thr  His Lys Gln Ala Val  Glu Thr Leu Arg Asn  Thr Gly Gln 
    1430                 1435                 1440             


Val Val  His Leu Leu Leu Glu  Lys Gly Gln Ser Pro  Thr Ser Lys 
    1445                 1450                 1455             


Glu His  Val Pro Val Thr Pro  Gln Cys Thr Leu Ser  Asp Gln Asn 
    1460                 1465                 1470             


Ala Gln  Gly Gln Gly Pro Glu  Lys Val Lys Lys Thr  Thr Gln Val 
    1475                 1480                 1485             


Lys Asp  Tyr Ser Phe Val Thr  Glu Glu Asn Thr Phe  Glu Val Lys 
    1490                 1495                 1500             


Leu Phe  Lys Asn Ser Ser Gly  Leu Gly Phe Ser Phe  Ser Arg Glu 
    1505                 1510                 1515             


Asp Asn  Leu Ile Pro Glu Gln  Ile Asn Ala Ser Ile  Val Arg Val 
    1520                 1525                 1530             


Lys Lys  Leu Phe Pro Gly Gln  Pro Ala Ala Glu Ser  Gly Lys Ile 
    1535                 1540                 1545             


Asp Val  Gly Asp Val Ile Leu  Lys Val Asn Gly Ala  Ser Leu Lys 
    1550                 1555                 1560             


Gly Leu  Ser Gln Gln Glu Val  Ile Ser Ala Leu Arg  Gly Thr Ala 
    1565                 1570                 1575             


Pro Glu  Val Phe Leu Leu Leu  Cys Arg Pro Pro Pro  Gly Val Leu 
    1580                 1585                 1590             


Pro Glu  Ile Asp Thr Ala Leu  Leu Thr Pro Leu Gln  Ser Pro Ala 
    1595                 1600                 1605             


Gln Val  Leu Pro Asn Ser Ser  Lys Asp Ser Ser Gln  Pro Ser Cys 
    1610                 1615                 1620             


Val Glu  Gln Ser Thr Ser Ser  Asp Glu Asn Glu Met  Ser Asp Lys 
    1625                 1630                 1635             


Ser Lys  Lys Gln Cys Lys Ser  Pro Ser Arg Arg Asp  Ser Tyr Ser 
    1640                 1645                 1650             


Asp Ser  Ser Gly Ser Gly Glu  Asp Asp Leu Val Thr  Ala Pro Ala 
    1655                 1660                 1665             


Asn Ile  Ser Asn Ser Thr Trp  Ser Ser Ala Leu His  Gln Thr Leu 
    1670                 1675                 1680             


Ser Asn  Met Val Ser Gln Ala  Gln Ser His His Glu  Ala Pro Lys 
    1685                 1690                 1695             


Ser Gln  Glu Asp Thr Ile Cys  Thr Met Phe Tyr Tyr  Pro Gln Lys 
    1700                 1705                 1710             


Ile Pro  Asn Lys Pro Glu Phe  Glu Asp Ser Asn Pro  Ser Pro Leu 
    1715                 1720                 1725             


Pro Pro  Asp Met Ala Pro Gly  Gln Ser Tyr Gln Pro  Gln Ser Glu 
    1730                 1735                 1740             


Ser Ala  Ser Ser Ser Ser Met  Asp Lys Tyr His Ile  His His Ile 
    1745                 1750                 1755             


Ser Glu  Pro Thr Arg Gln Glu  Asn Trp Thr Pro Leu  Lys Asn Asp 
    1760                 1765                 1770             


Leu Glu  Asn His Leu Glu Asp  Phe Glu Leu Glu Val  Glu Leu Leu 
    1775                 1780                 1785             


Ile Thr  Leu Ile Lys Ser Glu  Lys Gly Ser Leu Gly  Phe Thr Val 
    1790                 1795                 1800             


Thr Lys  Gly Asn Gln Arg Ile  Gly Cys Tyr Val His  Asp Val Ile 
    1805                 1810                 1815             


Gln Asp  Pro Ala Lys Ser Asp  Gly Arg Leu Lys Pro  Gly Asp Arg 
    1820                 1825                 1830             


Leu Ile  Lys Val Asn Asp Thr  Asp Val Thr Asn Met  Thr His Thr 
    1835                 1840                 1845             


Asp Ala  Val Asn Leu Leu Arg  Ala Ala Ser Lys Thr  Val Arg Leu 
    1850                 1855                 1860             


Val Ile  Gly Arg Val Leu Glu  Leu Pro Arg Ile Pro  Met Leu Pro 
    1865                 1870                 1875             


His Leu  Leu Pro Asp Ile Thr  Leu Thr Cys Asn Lys  Glu Glu Leu 
    1880                 1885                 1890             


Gly Phe  Ser Leu Cys Gly Gly  His Asp Ser Leu Tyr  Gln Val Val 
    1895                 1900                 1905             


Tyr Ile  Ser Asp Ile Asn Pro  Arg Ser Val Ala Ala  Ile Glu Gly 
    1910                 1915                 1920             


Asn Leu  Gln Leu Leu Asp Val  Ile His Tyr Val Asn  Gly Val Ser 
    1925                 1930                 1935             


Thr Gln  Gly Met Thr Leu Glu  Glu Val Asn Arg Ala  Leu Asp Met 
    1940                 1945                 1950             


Ser Leu  Pro Ser Leu Val Leu  Lys Ala Thr Arg Asn  Asp Leu Pro 
    1955                 1960                 1965             


Val Val  Pro Ser Ser Lys Arg  Ser Ala Val Ser Ala  Pro Lys Ser 
    1970                 1975                 1980             


Thr Lys  Gly Asn Gly Ser Tyr  Ser Val Gly Ser Cys  Ser Gln Pro 
    1985                 1990                 1995             


Ala Leu  Thr Pro Asn Asp Ser  Phe Ser Thr Val Ala  Gly Glu Glu 
    2000                 2005                 2010             


Ile Asn  Glu Ile Ser Tyr Pro  Lys Gly Lys Cys Ser  Thr Tyr Gln 
    2015                 2020                 2025             


Ile Lys  Gly Ser Pro Asn Leu  Thr Leu Pro Lys Glu  Ser Tyr Ile 
    2030                 2035                 2040             


Gln Glu  Asp Asp Ile Tyr Asp  Asp Ser Gln Glu Ala  Glu Val Ile 
    2045                 2050                 2055             


Gln Ser  Leu Leu Asp Val Val  Asp Glu Glu Ala Gln  Asn Leu Leu 
    2060                 2065                 2070             


Asn Glu  Asn Asn Ala Ala Gly  Tyr Ser Cys Gly Pro  Gly Thr Leu 
    2075                 2080                 2085             


Lys Met  Asn Gly Lys Leu Ser  Glu Glu Arg Thr Glu  Asp Thr Asp 
    2090                 2095                 2100             


Cys Asp  Gly Ser Pro Leu Pro  Glu Tyr Phe Thr Glu  Ala Thr Lys 
    2105                 2110                 2115             


Met Asn  Gly Cys Glu Glu Tyr  Cys Glu Glu Lys Val  Lys Ser Glu 
    2120                 2125                 2130             


Ser Leu  Ile Gln Lys Pro Gln  Glu Lys Lys Thr Asp  Asp Asp Glu 
    2135                 2140                 2145             


Ile Thr  Trp Gly Asn Asp Glu  Leu Pro Ile Glu Arg  Thr Asn His 
    2150                 2155                 2160             


Glu Asp  Ser Asp Lys Asp His  Ser Phe Leu Thr Asn  Asp Glu Leu 
    2165                 2170                 2175             


Ala Val  Leu Pro Val Val Lys  Val Leu Pro Ser Gly  Lys Tyr Thr 
    2180                 2185                 2190             


Gly Ala  Asn Leu Lys Ser Val  Ile Arg Val Leu Arg  Gly Leu Leu 
    2195                 2200                 2205             


Asp Gln  Gly Ile Pro Ser Lys  Glu Leu Glu Asn Leu  Gln Glu Leu 
    2210                 2215                 2220             


Lys Pro  Leu Asp Gln Cys Leu  Ile Gly Gln Thr Lys  Glu Asn Arg 
    2225                 2230                 2235             


Arg Lys  Asn Arg Tyr Lys Asn  Ile Leu Pro Tyr Asp  Ala Thr Arg 
    2240                 2245                 2250             


Val Pro  Leu Gly Asp Glu Gly  Gly Tyr Ile Asn Ala  Ser Phe Ile 
    2255                 2260                 2265             


Lys Ile  Pro Val Gly Lys Glu  Glu Phe Val Tyr Ile  Ala Cys Gln 
    2270                 2275                 2280             


Gly Pro  Leu Pro Thr Thr Val  Gly Asp Phe Trp Gln  Met Ile Trp 
    2285                 2290                 2295             


Glu Gln  Lys Ser Thr Val Ile  Ala Met Met Thr Gln  Glu Val Glu 
    2300                 2305                 2310             


Gly Glu  Lys Ile Lys Cys Gln  Arg Tyr Trp Pro Asn  Ile Leu Gly 
    2315                 2320                 2325             


Lys Thr  Thr Met Val Ser Asn  Arg Leu Arg Leu Ala  Leu Val Arg 
    2330                 2335                 2340             


Met Gln  Gln Leu Lys Gly Phe  Val Val Arg Ala Met  Thr Leu Glu 
    2345                 2350                 2355             


Asp Ile  Gln Thr Arg Glu Val  Arg His Ile Ser His  Leu Asn Phe 
    2360                 2365                 2370             


Thr Ala  Trp Pro Asp His Asp  Thr Pro Ser Gln Pro  Asp Asp Leu 
    2375                 2380                 2385             


Leu Thr  Phe Ile Ser Tyr Met  Arg His Ile His Arg  Ser Gly Pro 
    2390                 2395                 2400             


Ile Ile  Thr His Cys Ser Ala  Gly Ile Gly Arg Ser  Gly Thr Leu 
    2405                 2410                 2415             


Ile Cys  Ile Asp Val Val Leu  Gly Leu Ile Ser Gln  Asp Leu Asp 
    2420                 2425                 2430             


Phe Asp  Ile Ser Asp Leu Val  Arg Cys Met Arg Leu  Gln Arg His 
    2435                 2440                 2445             


Gly Met  Val Gln Thr Glu Asp  Gln Tyr Ile Phe Cys  Tyr Gln Val 
    2450                 2455                 2460             


Ile Leu  Tyr Val Leu Thr Arg  Leu Gln Ala Glu Glu  Glu Gln Lys 
    2465                 2470                 2475             


Gln Gln  Pro Gln Leu Leu Lys  
    2480                 2485 


<210>  3574
<211>  434
<212>  PRT
<213>  homo sapiens

<400>  3574

Met Asp Asp Gln Ser Arg Met Leu Gln Thr Leu Ala Gly Val Asn Leu 
1               5                   10                  15      


Ala Gly His Ser Val Gln Gly Gly Met Ala Leu Pro Pro Pro Pro His 
            20                  25                  30          


Gly His Glu Gly Ala Asp Gly Asp Gly Arg Lys Gln Asp Ile Gly Asp 
        35                  40                  45              


Ile Leu His Gln Ile Met Thr Ile Thr Asp Gln Ser Leu Asp Glu Ala 
    50                  55                  60                  


Gln Ala Lys Lys His Ala Leu Asn Cys His Arg Met Lys Pro Ala Leu 
65                  70                  75                  80  


Phe Ser Val Leu Cys Glu Ile Lys Glu Lys Thr Gly Leu Ser Ile Arg 
                85                  90                  95      


Gly Ala Gln Glu Glu Asp Pro Pro Asp Pro Gln Leu Met Arg Leu Asp 
            100                 105                 110         


Asn Met Leu Leu Ala Glu Gly Val Ser Gly Pro Glu Lys Gly Gly Gly 
        115                 120                 125             


Ser Ala Ala Ala Ala Ala Ala Ala Ala Ala Ser Gly Gly Ser Ser Asp 
    130                 135                 140                 


Asn Ser Ile Glu His Ser Asp Tyr Arg Ala Lys Leu Thr Gln Ile Arg 
145                 150                 155                 160 


Gln Ile Tyr His Thr Glu Leu Glu Lys Tyr Glu Gln Ala Cys Asn Glu 
                165                 170                 175     


Phe Thr Thr His Val Met Asn Leu Leu Arg Glu Gln Ser Arg Thr Arg 
            180                 185                 190         


Pro Ile Ser Pro Lys Glu Ile Glu Arg Met Val Gly Ile Ile His Arg 
        195                 200                 205             


Lys Phe Ser Ser Ile Gln Met Gln Leu Lys Gln Ser Thr Cys Glu Ala 
    210                 215                 220                 


Val Met Ile Leu Arg Ser Arg Phe Leu Asp Ala Arg Arg Lys Arg Arg 
225                 230                 235                 240 


Asn Phe Ser Lys Gln Ala Thr Glu Ile Leu Asn Glu Tyr Phe Tyr Ser 
                245                 250                 255     


His Leu Ser Asn Pro Tyr Pro Ser Glu Glu Ala Lys Glu Glu Leu Ala 
            260                 265                 270         


Lys Lys Cys Ser Ile Thr Val Ser Gln Val Ser Asn Trp Phe Gly Asn 
        275                 280                 285             


Lys Arg Ile Arg Tyr Lys Lys Asn Ile Gly Lys Phe Gln Glu Glu Ala 
    290                 295                 300                 


Asn Leu Tyr Ala Ala Lys Thr Ala Val Thr Ala Ala His Ala Val Ala 
305                 310                 315                 320 


Ala Ala Val Gln Asn Asn Gln Thr Asn Ser Pro Thr Thr Pro Asn Ser 
                325                 330                 335     


Gly Ser Ser Gly Ser Phe Asn Leu Pro Asn Ser Gly Asp Met Phe Met 
            340                 345                 350         


Asn Met Gln Ser Leu Asn Gly Asp Ser Tyr Gln Gly Ser Gln Val Gly 
        355                 360                 365             


Ala Asn Val Gln Ser Gln Val Asp Thr Leu Arg His Val Ile Asn Gln 
    370                 375                 380                 


Thr Gly Gly Tyr Ser Asp Gly Leu Gly Gly Asn Ser Leu Tyr Ser Pro 
385                 390                 395                 400 


His Asn Leu Asn Ala Asn Gly Gly Trp Gln Asp Ala Thr Thr Pro Ser 
                405                 410                 415     


Ser Val Thr Ser Pro Thr Glu Gly Pro Gly Ser Val His Ser Asp Thr 
            420                 425                 430         


Ser Asn 
        


<210>  3575
<211>  359
<212>  PRT
<213>  homo sapiens

<400>  3575

Met Lys Pro Ala Leu Phe Ser Val Leu Cys Glu Ile Lys Glu Lys Thr 
1               5                   10                  15      


Gly Leu Ser Ile Arg Gly Ala Gln Glu Glu Asp Pro Pro Asp Pro Gln 
            20                  25                  30          


Leu Met Arg Leu Asp Asn Met Leu Leu Ala Glu Gly Val Ser Gly Pro 
        35                  40                  45              


Glu Lys Gly Gly Gly Ser Ala Ala Ala Ala Ala Ala Ala Ala Ala Ser 
    50                  55                  60                  


Gly Gly Ser Ser Asp Asn Ser Ile Glu His Ser Asp Tyr Arg Ala Lys 
65                  70                  75                  80  


Leu Thr Gln Ile Arg Gln Ile Tyr His Thr Glu Leu Glu Lys Tyr Glu 
                85                  90                  95      


Gln Ala Cys Asn Glu Phe Thr Thr His Val Met Asn Leu Leu Arg Glu 
            100                 105                 110         


Gln Ser Arg Thr Arg Pro Ile Ser Pro Lys Glu Ile Glu Arg Met Val 
        115                 120                 125             


Gly Ile Ile His Arg Lys Phe Ser Ser Ile Gln Met Gln Leu Lys Gln 
    130                 135                 140                 


Ser Thr Cys Glu Ala Val Met Ile Leu Arg Ser Arg Phe Leu Asp Ala 
145                 150                 155                 160 


Arg Arg Lys Arg Arg Asn Phe Ser Lys Gln Ala Thr Glu Ile Leu Asn 
                165                 170                 175     


Glu Tyr Phe Tyr Ser His Leu Ser Asn Pro Tyr Pro Ser Glu Glu Ala 
            180                 185                 190         


Lys Glu Glu Leu Ala Lys Lys Cys Ser Ile Thr Val Ser Gln Val Ser 
        195                 200                 205             


Asn Trp Phe Gly Asn Lys Arg Ile Arg Tyr Lys Lys Asn Ile Gly Lys 
    210                 215                 220                 


Phe Gln Glu Glu Ala Asn Leu Tyr Ala Ala Lys Thr Ala Val Thr Ala 
225                 230                 235                 240 


Ala His Ala Val Ala Ala Ala Val Gln Asn Asn Gln Thr Asn Ser Pro 
                245                 250                 255     


Thr Thr Pro Asn Ser Gly Ser Ser Gly Ser Phe Asn Leu Pro Asn Ser 
            260                 265                 270         


Gly Asp Met Phe Met Asn Met Gln Ser Leu Asn Gly Asp Ser Tyr Gln 
        275                 280                 285             


Gly Ser Gln Val Gly Ala Asn Val Gln Ser Gln Val Asp Thr Leu Arg 
    290                 295                 300                 


His Val Ile Asn Gln Thr Gly Gly Tyr Ser Asp Gly Leu Gly Gly Asn 
305                 310                 315                 320 


Ser Leu Tyr Ser Pro His Asn Leu Asn Ala Asn Gly Gly Trp Gln Asp 
                325                 330                 335     


Ala Thr Thr Pro Ser Ser Val Thr Ser Pro Thr Glu Gly Pro Gly Ser 
            340                 345                 350         


Val His Ser Asp Thr Ser Asn 
        355                 


<210>  3576
<211>  896
<212>  PRT
<213>  homo sapiens

<400>  3576

Met Ile Val Leu Leu Leu Phe Ala Leu Leu Trp Met Val Glu Gly Val 
1               5                   10                  15      


Phe Ser Gln Leu His Tyr Thr Val Gln Glu Glu Gln Glu His Gly Thr 
            20                  25                  30          


Phe Val Gly Asn Ile Ala Glu Asp Leu Gly Leu Asp Ile Thr Lys Leu 
        35                  40                  45              


Ser Ala Arg Gly Phe Gln Thr Val Pro Asn Ser Arg Thr Pro Tyr Leu 
    50                  55                  60                  


Asp Leu Asn Leu Glu Thr Gly Val Leu Tyr Val Asn Glu Lys Ile Asp 
65                  70                  75                  80  


Arg Glu Gln Ile Cys Lys Gln Ser Pro Ser Cys Val Leu His Leu Glu 
                85                  90                  95      


Val Phe Leu Glu Asn Pro Leu Glu Leu Phe Gln Val Glu Ile Glu Val 
            100                 105                 110         


Leu Asp Ile Asn Asp Asn Pro Pro Ser Phe Pro Glu Pro Asp Leu Thr 
        115                 120                 125             


Val Glu Ile Ser Glu Ser Ala Thr Pro Gly Thr Arg Phe Pro Leu Glu 
    130                 135                 140                 


Ser Ala Phe Asp Pro Asp Val Gly Thr Asn Ser Leu Arg Asp Tyr Glu 
145                 150                 155                 160 


Ile Thr Pro Asn Ser Tyr Phe Ser Leu Asp Val Gln Thr Gln Gly Asp 
                165                 170                 175     


Gly Asn Arg Phe Ala Glu Leu Val Leu Glu Lys Pro Leu Asp Arg Glu 
            180                 185                 190         


Gln Gln Ala Val His Arg Tyr Val Leu Thr Ala Val Asp Gly Gly Gly 
        195                 200                 205             


Gly Gly Gly Val Gly Glu Gly Gly Gly Gly Gly Gly Gly Ala Gly Leu 
    210                 215                 220                 


Pro Pro Gln Gln Gln Arg Thr Gly Thr Ala Leu Leu Thr Ile Arg Val 
225                 230                 235                 240 


Leu Asp Ser Asn Asp Asn Val Pro Ala Phe Asp Gln Pro Val Tyr Thr 
                245                 250                 255     


Val Ser Leu Pro Glu Asn Ser Pro Pro Gly Thr Leu Val Ile Gln Leu 
            260                 265                 270         


Asn Ala Thr Asp Pro Asp Glu Gly Gln Asn Gly Glu Val Val Tyr Ser 
        275                 280                 285             


Phe Ser Ser His Ile Ser Pro Arg Ala Arg Glu Leu Phe Gly Leu Ser 
    290                 295                 300                 


Pro Arg Thr Gly Arg Leu Glu Val Ser Gly Glu Leu Asp Tyr Glu Glu 
305                 310                 315                 320 


Ser Pro Val Tyr Gln Val Tyr Val Gln Ala Lys Asp Leu Gly Pro Asn 
                325                 330                 335     


Ala Val Pro Ala His Cys Lys Val Leu Val Arg Val Leu Asp Ala Asn 
            340                 345                 350         


Asp Asn Ala Pro Glu Ile Ser Phe Ser Thr Val Lys Glu Ala Val Ser 
        355                 360                 365             


Glu Gly Ala Ala Pro Gly Thr Val Val Ala Leu Phe Ser Val Thr Asp 
    370                 375                 380                 


Arg Asp Ser Glu Glu Asn Gly Gln Val Gln Cys Glu Leu Leu Gly Asp 
385                 390                 395                 400 


Val Pro Phe Arg Leu Lys Ser Ser Phe Lys Asn Tyr Tyr Thr Ile Val 
                405                 410                 415     


Thr Glu Ala Pro Leu Asp Arg Glu Ala Gly Asp Ser Tyr Thr Leu Thr 
            420                 425                 430         


Val Val Ala Arg Asp Arg Gly Glu Pro Ala Leu Ser Thr Ser Lys Ser 
        435                 440                 445             


Ile Gln Val Gln Val Ser Asp Val Asn Asp Asn Ala Pro Arg Phe Ser 
    450                 455                 460                 


Gln Pro Val Tyr Asp Val Tyr Val Thr Glu Asn Asn Val Pro Gly Ala 
465                 470                 475                 480 


Tyr Ile Tyr Ala Val Ser Ala Thr Asp Arg Asp Glu Gly Ala Asn Ala 
                485                 490                 495     


Gln Leu Ala Tyr Ser Ile Leu Glu Cys Gln Ile Gln Gly Met Ser Val 
            500                 505                 510         


Phe Thr Tyr Val Ser Ile Asn Ser Glu Asn Gly Tyr Leu Tyr Ala Leu 
        515                 520                 525             


Arg Ser Phe Asp Tyr Glu Gln Leu Lys Asp Phe Ser Phe Gln Val Glu 
    530                 535                 540                 


Ala Arg Asp Ala Gly Ser Pro Gln Ala Leu Ala Gly Asn Ala Thr Val 
545                 550                 555                 560 


Asn Ile Leu Ile Val Asp Gln Asn Asp Asn Ala Pro Ala Ile Val Ala 
                565                 570                 575     


Pro Leu Pro Gly Arg Asn Gly Thr Pro Ala Arg Glu Val Leu Pro Arg 
            580                 585                 590         


Ser Ala Glu Pro Gly Tyr Leu Leu Thr Arg Val Ala Ala Val Asp Ala 
        595                 600                 605             


Asp Asp Gly Glu Asn Ala Arg Leu Thr Tyr Ser Ile Val Arg Gly Asn 
    610                 615                 620                 


Glu Met Asn Leu Phe Arg Met Asp Trp Arg Thr Gly Glu Leu Arg Thr 
625                 630                 635                 640 


Ala Arg Arg Val Pro Ala Lys Arg Asp Pro Gln Arg Pro Tyr Glu Leu 
                645                 650                 655     


Val Ile Glu Val Arg Asp His Gly Gln Pro Pro Leu Ser Ser Thr Ala 
            660                 665                 670         


Thr Leu Val Val Gln Leu Val Asp Gly Ala Val Glu Pro Gln Gly Gly 
        675                 680                 685             


Gly Gly Ser Gly Gly Gly Gly Ser Gly Glu His Gln Arg Pro Ser Arg 
    690                 695                 700                 


Ser Gly Gly Gly Glu Thr Ser Leu Asp Leu Thr Leu Ile Leu Ile Ile 
705                 710                 715                 720 


Ala Leu Gly Ser Val Ser Phe Ile Phe Leu Leu Ala Met Ile Val Leu 
                725                 730                 735     


Ala Val Arg Cys Gln Lys Glu Lys Lys Leu Asn Ile Tyr Thr Cys Leu 
            740                 745                 750         


Ala Ser Asp Cys Cys Leu Cys Cys Cys Cys Cys Gly Gly Gly Gly Ser 
        755                 760                 765             


Thr Cys Cys Gly Arg Gln Ala Arg Ala Arg Lys Lys Lys Leu Ser Lys 
    770                 775                 780                 


Ser Asp Ile Met Leu Val Gln Ser Ser Asn Val Pro Ser Asn Pro Ala 
785                 790                 795                 800 


Gln Val Pro Ile Glu Glu Ser Gly Gly Phe Gly Ser His His His Asn 
                805                 810                 815     


Gln Asn Tyr Cys Tyr Gln Val Cys Leu Thr Pro Glu Ser Ala Lys Thr 
            820                 825                 830         


Asp Leu Met Phe Leu Lys Pro Cys Ser Pro Ser Arg Ser Thr Asp Thr 
        835                 840                 845             


Glu His Asn Pro Cys Gly Ala Ile Val Thr Gly Tyr Thr Asp Gln Gln 
    850                 855                 860                 


Pro Asp Ile Ile Ser Asn Gly Ser Ile Leu Ser Asn Glu Val Arg Leu 
865                 870                 875                 880 


Lys Arg Lys Asp His His Leu Ser Ser Pro Pro Ser Glu Ser Leu Leu 
                885                 890                 895     


<210>  3577
<211>  1040
<212>  PRT
<213>  homo sapiens

<400>  3577

Met Ile Val Leu Leu Leu Phe Ala Leu Leu Trp Met Val Glu Gly Val 
1               5                   10                  15      


Phe Ser Gln Leu His Tyr Thr Val Gln Glu Glu Gln Glu His Gly Thr 
            20                  25                  30          


Phe Val Gly Asn Ile Ala Glu Asp Leu Gly Leu Asp Ile Thr Lys Leu 
        35                  40                  45              


Ser Ala Arg Gly Phe Gln Thr Val Pro Asn Ser Arg Thr Pro Tyr Leu 
    50                  55                  60                  


Asp Leu Asn Leu Glu Thr Gly Val Leu Tyr Val Asn Glu Lys Ile Asp 
65                  70                  75                  80  


Arg Glu Gln Ile Cys Lys Gln Ser Pro Ser Cys Val Leu His Leu Glu 
                85                  90                  95      


Val Phe Leu Glu Asn Pro Leu Glu Leu Phe Gln Val Glu Ile Glu Val 
            100                 105                 110         


Leu Asp Ile Asn Asp Asn Pro Pro Ser Phe Pro Glu Pro Asp Leu Thr 
        115                 120                 125             


Val Glu Ile Ser Glu Ser Ala Thr Pro Gly Thr Arg Phe Pro Leu Glu 
    130                 135                 140                 


Ser Ala Phe Asp Pro Asp Val Gly Thr Asn Ser Leu Arg Asp Tyr Glu 
145                 150                 155                 160 


Ile Thr Pro Asn Ser Tyr Phe Ser Leu Asp Val Gln Thr Gln Gly Asp 
                165                 170                 175     


Gly Asn Arg Phe Ala Glu Leu Val Leu Glu Lys Pro Leu Asp Arg Glu 
            180                 185                 190         


Gln Gln Ala Val His Arg Tyr Val Leu Thr Ala Val Asp Gly Gly Gly 
        195                 200                 205             


Gly Gly Gly Val Gly Glu Gly Gly Gly Gly Gly Gly Gly Ala Gly Leu 
    210                 215                 220                 


Pro Pro Gln Gln Gln Arg Thr Gly Thr Ala Leu Leu Thr Ile Arg Val 
225                 230                 235                 240 


Leu Asp Ser Asn Asp Asn Val Pro Ala Phe Asp Gln Pro Val Tyr Thr 
                245                 250                 255     


Val Ser Leu Pro Glu Asn Ser Pro Pro Gly Thr Leu Val Ile Gln Leu 
            260                 265                 270         


Asn Ala Thr Asp Pro Asp Glu Gly Gln Asn Gly Glu Val Val Tyr Ser 
        275                 280                 285             


Phe Ser Ser His Ile Ser Pro Arg Ala Arg Glu Leu Phe Gly Leu Ser 
    290                 295                 300                 


Pro Arg Thr Gly Arg Leu Glu Val Ser Gly Glu Leu Asp Tyr Glu Glu 
305                 310                 315                 320 


Ser Pro Val Tyr Gln Val Tyr Val Gln Ala Lys Asp Leu Gly Pro Asn 
                325                 330                 335     


Ala Val Pro Ala His Cys Lys Val Leu Val Arg Val Leu Asp Ala Asn 
            340                 345                 350         


Asp Asn Ala Pro Glu Ile Ser Phe Ser Thr Val Lys Glu Ala Val Ser 
        355                 360                 365             


Glu Gly Ala Ala Pro Gly Thr Val Val Ala Leu Phe Ser Val Thr Asp 
    370                 375                 380                 


Arg Asp Ser Glu Glu Asn Gly Gln Val Gln Cys Glu Leu Leu Gly Asp 
385                 390                 395                 400 


Val Pro Phe Arg Leu Lys Ser Ser Phe Lys Asn Tyr Tyr Thr Ile Val 
                405                 410                 415     


Thr Glu Ala Pro Leu Asp Arg Glu Ala Gly Asp Ser Tyr Thr Leu Thr 
            420                 425                 430         


Val Val Ala Arg Asp Arg Gly Glu Pro Ala Leu Ser Thr Ser Lys Ser 
        435                 440                 445             


Ile Gln Val Gln Val Ser Asp Val Asn Asp Asn Ala Pro Arg Phe Ser 
    450                 455                 460                 


Gln Pro Val Tyr Asp Val Tyr Val Thr Glu Asn Asn Val Pro Gly Ala 
465                 470                 475                 480 


Tyr Ile Tyr Ala Val Ser Ala Thr Asp Arg Asp Glu Gly Ala Asn Ala 
                485                 490                 495     


Gln Leu Ala Tyr Ser Ile Leu Glu Cys Gln Ile Gln Gly Met Ser Val 
            500                 505                 510         


Phe Thr Tyr Val Ser Ile Asn Ser Glu Asn Gly Tyr Leu Tyr Ala Leu 
        515                 520                 525             


Arg Ser Phe Asp Tyr Glu Gln Leu Lys Asp Phe Ser Phe Gln Val Glu 
    530                 535                 540                 


Ala Arg Asp Ala Gly Ser Pro Gln Ala Leu Ala Gly Asn Ala Thr Val 
545                 550                 555                 560 


Asn Ile Leu Ile Val Asp Gln Asn Asp Asn Ala Pro Ala Ile Val Ala 
                565                 570                 575     


Pro Leu Pro Gly Arg Asn Gly Thr Pro Ala Arg Glu Val Leu Pro Arg 
            580                 585                 590         


Ser Ala Glu Pro Gly Tyr Leu Leu Thr Arg Val Ala Ala Val Asp Ala 
        595                 600                 605             


Asp Asp Gly Glu Asn Ala Arg Leu Thr Tyr Ser Ile Val Arg Gly Asn 
    610                 615                 620                 


Glu Met Asn Leu Phe Arg Met Asp Trp Arg Thr Gly Glu Leu Arg Thr 
625                 630                 635                 640 


Ala Arg Arg Val Pro Ala Lys Arg Asp Pro Gln Arg Pro Tyr Glu Leu 
                645                 650                 655     


Val Ile Glu Val Arg Asp His Gly Gln Pro Pro Leu Ser Ser Thr Ala 
            660                 665                 670         


Thr Leu Val Val Gln Leu Val Asp Gly Ala Val Glu Pro Gln Gly Gly 
        675                 680                 685             


Gly Gly Ser Gly Gly Gly Gly Ser Gly Glu His Gln Arg Pro Ser Arg 
    690                 695                 700                 


Ser Gly Gly Gly Glu Thr Ser Leu Asp Leu Thr Leu Ile Leu Ile Ile 
705                 710                 715                 720 


Ala Leu Gly Ser Val Ser Phe Ile Phe Leu Leu Ala Met Ile Val Leu 
                725                 730                 735     


Ala Val Arg Cys Gln Lys Glu Lys Lys Leu Asn Ile Tyr Thr Cys Leu 
            740                 745                 750         


Ala Ser Asp Cys Cys Leu Cys Cys Cys Cys Cys Gly Gly Gly Gly Ser 
        755                 760                 765             


Thr Cys Cys Gly Arg Gln Ala Arg Ala Arg Lys Lys Lys Leu Ser Lys 
    770                 775                 780                 


Ser Asp Ile Met Leu Val Gln Ser Ser Asn Val Pro Ser Asn Pro Ala 
785                 790                 795                 800 


Gln Val Pro Ile Glu Glu Ser Gly Gly Phe Gly Ser His His His Asn 
                805                 810                 815     


Gln Asn Tyr Cys Tyr Gln Val Cys Leu Thr Pro Glu Ser Ala Lys Thr 
            820                 825                 830         


Asp Leu Met Phe Leu Lys Pro Cys Ser Pro Ser Arg Ser Thr Asp Thr 
        835                 840                 845             


Glu His Asn Pro Cys Gly Ala Ile Val Thr Gly Tyr Thr Asp Gln Gln 
    850                 855                 860                 


Pro Asp Ile Ile Ser Asn Gly Ser Ile Leu Ser Asn Glu Thr Lys His 
865                 870                 875                 880 


Gln Arg Ala Glu Leu Ser Tyr Leu Val Asp Arg Pro Arg Arg Val Asn 
                885                 890                 895     


Ser Ser Ala Phe Gln Glu Ala Asp Ile Val Ser Ser Lys Asp Ser Gly 
            900                 905                 910         


His Gly Asp Ser Glu Gln Gly Asp Ser Asp His Asp Ala Thr Asn Arg 
        915                 920                 925             


Ala Gln Ser Ala Gly Met Asp Leu Phe Ser Asn Cys Thr Glu Glu Cys 
    930                 935                 940                 


Lys Ala Leu Gly His Ser Asp Arg Cys Trp Met Pro Ser Phe Val Pro 
945                 950                 955                 960 


Ser Asp Gly Arg Gln Ala Ala Asp Tyr Arg Ser Asn Leu His Val Pro 
                965                 970                 975     


Gly Met Asp Ser Val Pro Asp Thr Glu Val Phe Glu Thr Pro Glu Ala 
            980                 985                 990         


Gln Pro Gly Ala Glu Arg Ser Phe  Ser Thr Phe Gly Lys  Glu Lys Ala 
        995                 1000                 1005             


Leu His  Ser Thr Leu Glu Arg  Lys Glu Leu Asp Gly  Leu Leu Thr 
    1010                 1015                 1020             


Asn Thr  Arg Ala Pro Tyr Lys  Pro Pro Tyr Leu Thr  Arg Lys Arg 
    1025                 1030                 1035             


Ile Cys  
    1040 


<210>  3578
<211>  1070
<212>  PRT
<213>  homo sapiens

<400>  3578

Met Ser Pro Val Arg Arg Trp Gly Ser Pro Cys Leu Phe Pro Leu Gln 
1               5                   10                  15      


Leu Phe Ser Leu Cys Trp Val Leu Ser Val Ala Gln Ser Lys Thr Val 
            20                  25                  30          


Arg Tyr Ser Thr Phe Glu Glu Asp Ala Pro Gly Thr Val Ile Gly Thr 
        35                  40                  45              


Leu Ala Glu Asp Leu His Met Lys Val Ser Gly Asp Thr Ser Phe Arg 
    50                  55                  60                  


Leu Met Lys Gln Phe Asn Ser Ser Leu Leu Arg Val Arg Glu Gly Asp 
65                  70                  75                  80  


Gly Gln Leu Thr Val Gly Asp Ala Gly Leu Asp Arg Glu Arg Leu Cys 
                85                  90                  95      


Gly Gln Ala Pro Gln Cys Val Leu Ala Phe Asp Val Val Ser Phe Ser 
            100                 105                 110         


Gln Glu Gln Phe Arg Leu Val His Val Glu Val Glu Val Arg Asp Val 
        115                 120                 125             


Asn Asp His Ala Pro Arg Phe Pro Arg Ala Gln Ile Pro Val Glu Val 
    130                 135                 140                 


Ser Glu Gly Ala Ala Val Gly Thr Arg Ile Pro Leu Glu Val Pro Val 
145                 150                 155                 160 


Asp Glu Asp Val Gly Ala Asn Gly Leu Gln Thr Val Arg Leu Ala Glu 
                165                 170                 175     


Pro His Ser Pro Phe Arg Val Glu Leu Gln Thr Arg Ala Asp Gly Ala 
            180                 185                 190         


Gln Cys Ala Asp Leu Val Leu Leu Gln Glu Leu Asp Arg Glu Ser Gln 
        195                 200                 205             


Ala Ala Tyr Ser Leu Glu Leu Val Ala Gln Asp Gly Gly Arg Pro Pro 
    210                 215                 220                 


Arg Ser Ala Thr Ala Ala Leu Ser Val Arg Val Leu Asp Ala Asn Asp 
225                 230                 235                 240 


His Ser Pro Ala Phe Pro Gln Gly Ala Val Ala Glu Val Glu Leu Ala 
                245                 250                 255     


Glu Asp Ala Pro Val Gly Ser Leu Leu Leu Asp Leu Asp Ala Ala Asp 
            260                 265                 270         


Pro Asp Glu Gly Pro Asn Gly Asp Val Val Phe Ala Phe Gly Ala Arg 
        275                 280                 285             


Thr Pro Pro Glu Ala Arg Arg Leu Phe Arg Leu Asp Pro Arg Ser Gly 
    290                 295                 300                 


Arg Leu Thr Leu Ala Gly Pro Val Asp Tyr Glu Arg Gln Asp Thr Tyr 
305                 310                 315                 320 


Glu Leu Asp Val Arg Ala Gln Asp Arg Gly Pro Gly Pro Arg Ala Ala 
                325                 330                 335     


Thr Cys Lys Val Ile Val Arg Ile Arg Asp Val Asn Asp Asn Ala Pro 
            340                 345                 350         


Asp Ile Ala Ile Thr Pro Leu Ala Ala Pro Gly Ala Pro Ala Thr Ser 
        355                 360                 365             


Pro Phe Ala Ala Ala Ala Ala Ala Ala Ala Leu Gly Gly Ala Asp Ala 
    370                 375                 380                 


Ser Ser Pro Ala Gly Ala Gly Thr Pro Glu Ala Gly Ala Thr Ser Leu 
385                 390                 395                 400 


Val Pro Glu Gly Ala Ala Arg Glu Ser Leu Val Ala Leu Val Ser Thr 
                405                 410                 415     


Ser Asp Arg Asp Ser Gly Ala Asn Gly Gln Val Arg Cys Ala Leu Tyr 
            420                 425                 430         


Gly His Glu His Phe Arg Leu Gln Pro Ala Tyr Ala Gly Ser Tyr Leu 
        435                 440                 445             


Val Val Thr Ala Ala Ser Leu Asp Arg Glu Arg Ile Ala Glu Tyr Asn 
    450                 455                 460                 


Leu Thr Leu Val Ala Glu Asp Arg Gly Ala Pro Pro Leu Arg Thr Val 
465                 470                 475                 480 


Arg Pro Tyr Thr Val Arg Val Gly Asp Glu Asn Asp Asn Ala Pro Leu 
                485                 490                 495     


Phe Thr Arg Pro Val Tyr Glu Val Ser Val Arg Glu Asn Asn Pro Pro 
            500                 505                 510         


Gly Ala Tyr Leu Ala Thr Val Ala Ala Arg Asp Arg Asp Leu Gly Arg 
        515                 520                 525             


Asn Gly Gln Val Thr Tyr Arg Leu Leu Glu Ala Glu Val Gly Arg Ala 
    530                 535                 540                 


Gly Gly Ala Val Ser Thr Tyr Val Ser Val Asp Pro Ala Thr Gly Ala 
545                 550                 555                 560 


Ile Tyr Ala Leu Arg Ser Phe Asp Tyr Glu Thr Leu Arg Gln Leu Asp 
                565                 570                 575     


Val Arg Ile Gln Ala Ser Asp Gly Gly Ser Pro Gln Leu Ser Ser Ser 
            580                 585                 590         


Ala Leu Val Gln Val Arg Val Leu Asp Gln Asn Asp His Ala Pro Val 
        595                 600                 605             


Leu Val His Pro Ala Pro Ala Asn Gly Ser Leu Glu Val Ala Val Pro 
    610                 615                 620                 


Gly Arg Thr Ala Lys Asp Thr Val Val Ala Arg Val Gln Ala Arg Asp 
625                 630                 635                 640 


Ala Asp Glu Gly Ala Asn Gly Glu Leu Ala Phe Glu Leu Gln Gln Gln 
                645                 650                 655     


Glu Pro Arg Glu Ala Phe Ala Ile Gly Arg Arg Thr Gly Glu Ile Leu 
            660                 665                 670         


Leu Thr Gly Asp Leu Ser Gln Glu Pro Pro Gly Arg Val Phe Arg Ala 
        675                 680                 685             


Leu Leu Val Ile Ser Asp Gly Gly Arg Pro Pro Leu Thr Thr Thr Ala 
    690                 695                 700                 


Thr Val Ser Phe Val Val Thr Ala Gly Gly Gly Arg Gly Pro Ala Ala 
705                 710                 715                 720 


Pro Ala Ser Ala Gly Ser Pro Glu Arg Ser Arg Pro Pro Gly Ser Arg 
                725                 730                 735     


Leu Gly Val Ser Gly Ser Val Leu Gln Trp Asp Thr Pro Leu Ile Val 
            740                 745                 750         


Ile Ile Val Leu Ala Gly Ser Cys Thr Leu Leu Leu Ala Ala Ile Ile 
        755                 760                 765             


Ala Ile Ala Thr Thr Cys Asn Arg Arg Lys Lys Glu Val Arg Lys Gly 
    770                 775                 780                 


Gly Ala Leu Arg Glu Glu Arg Pro Gly Ala Ala Gly Gly Gly Ala Ser 
785                 790                 795                 800 


Ala Pro Gly Ser Pro Glu Glu Ala Ala Arg Gly Ala Gly Pro Arg Pro 
                805                 810                 815     


Asn Met Phe Asp Val Leu Thr Phe Pro Gly Thr Gly Lys Ala Pro Phe 
            820                 825                 830         


Gly Ser Pro Ala Ala Asp Ala Pro Pro Pro Ala Val Ala Ala Ala Glu 
        835                 840                 845             


Val Pro Gly Ser Glu Gly Gly Ser Ala Thr Gly Glu Ser Ala Cys His 
    850                 855                 860                 


Phe Glu Gly Gln Gln Arg Leu Arg Gly Ala His Ala Glu Pro Tyr Gly 
865                 870                 875                 880 


Ala Ser Pro Gly Phe Gly Lys Glu Pro Ala Pro Pro Val Ala Val Trp 
                885                 890                 895     


Lys Gly His Ser Phe Asn Thr Ile Ser Gly Arg Glu Ala Glu Lys Phe 
            900                 905                 910         


Ser Gly Lys Asp Ser Gly Lys Gly Asp Ser Asp Phe Asn Asp Ser Asp 
        915                 920                 925             


Ser Asp Ile Ser Gly Asp Ala Leu Lys Lys Asp Leu Ile Asn His Met 
    930                 935                 940                 


Gln Ser Gly Leu Trp Ala Cys Thr Ala Glu Cys Lys Ile Leu Gly His 
945                 950                 955                 960 


Ser Asp Arg Cys Trp Ser Pro Ser Cys Ser Gly Pro Asn Ala His Pro 
                965                 970                 975     


Ser Pro His Pro Pro Ala Gln Met Ser Thr Phe Cys Lys Ser Thr Ser 
            980                 985                 990         


Leu Pro Arg Asp Pro Leu Arg Arg  Asp Asn Tyr Tyr Gln  Ala Gln Leu 
        995                 1000                 1005             


Pro Lys  Thr Val Gly Leu Gln  Ser Val Tyr Glu Lys  Val Leu His 
    1010                 1015                 1020             


Arg Asp  Tyr Asp Arg Thr Val  Thr Leu Leu Ser Pro  Pro Arg Pro 
    1025                 1030                 1035             


Gly Arg  Leu Pro Asp Leu Gln  Glu Ile Gly Val Pro  Leu Tyr Gln 
    1040                 1045                 1050             


Ser Pro  Pro Gly Arg Tyr Leu  Ser Pro Lys Lys Gly  Ala Asn Glu 
    1055                 1060                 1065             


Asn Val  
    1070 


<210>  3579
<211>  973
<212>  PRT
<213>  homo sapiens

<400>  3579

Met Ser Pro Val Arg Arg Trp Gly Ser Pro Cys Leu Phe Pro Leu Gln 
1               5                   10                  15      


Leu Phe Ser Leu Cys Trp Val Leu Ser Val Ala Gln Ser Lys Thr Val 
            20                  25                  30          


Arg Tyr Ser Thr Phe Glu Glu Asp Ala Pro Gly Thr Val Ile Gly Thr 
        35                  40                  45              


Leu Ala Glu Asp Leu His Met Lys Val Ser Gly Asp Thr Ser Phe Arg 
    50                  55                  60                  


Leu Met Lys Gln Phe Asn Ser Ser Leu Leu Arg Val Arg Glu Gly Asp 
65                  70                  75                  80  


Gly Gln Leu Thr Val Gly Asp Ala Gly Leu Asp Arg Glu Arg Leu Cys 
                85                  90                  95      


Gly Gln Ala Pro Gln Cys Val Leu Ala Phe Asp Val Val Ser Phe Ser 
            100                 105                 110         


Gln Glu Gln Phe Arg Leu Val His Val Glu Val Glu Val Arg Asp Val 
        115                 120                 125             


Asn Asp His Ala Pro Arg Phe Pro Arg Ala Gln Ile Pro Val Glu Val 
    130                 135                 140                 


Ser Glu Gly Ala Ala Val Gly Thr Arg Ile Pro Leu Glu Val Pro Val 
145                 150                 155                 160 


Asp Glu Asp Val Gly Ala Asn Gly Leu Gln Thr Val Arg Leu Ala Glu 
                165                 170                 175     


Pro His Ser Pro Phe Arg Val Glu Leu Gln Thr Arg Ala Asp Gly Ala 
            180                 185                 190         


Gln Cys Ala Asp Leu Val Leu Leu Gln Glu Leu Asp Arg Glu Ser Gln 
        195                 200                 205             


Ala Ala Tyr Ser Leu Glu Leu Val Ala Gln Asp Gly Gly Arg Pro Pro 
    210                 215                 220                 


Arg Ser Ala Thr Ala Ala Leu Ser Val Arg Val Leu Asp Ala Asn Asp 
225                 230                 235                 240 


His Ser Pro Ala Phe Pro Gln Gly Ala Val Ala Glu Val Glu Leu Ala 
                245                 250                 255     


Glu Asp Ala Pro Val Gly Ser Leu Leu Leu Asp Leu Asp Ala Ala Asp 
            260                 265                 270         


Pro Asp Glu Gly Pro Asn Gly Asp Val Val Phe Ala Phe Gly Ala Arg 
        275                 280                 285             


Thr Pro Pro Glu Ala Arg Arg Leu Phe Arg Leu Asp Pro Arg Ser Gly 
    290                 295                 300                 


Arg Leu Thr Leu Ala Gly Pro Val Asp Tyr Glu Arg Gln Asp Thr Tyr 
305                 310                 315                 320 


Glu Leu Asp Val Arg Ala Gln Asp Arg Gly Pro Gly Pro Arg Ala Ala 
                325                 330                 335     


Thr Cys Lys Val Ile Val Arg Ile Arg Asp Val Asn Asp Asn Ala Pro 
            340                 345                 350         


Asp Ile Ala Ile Thr Pro Leu Ala Ala Pro Gly Ala Pro Ala Thr Ser 
        355                 360                 365             


Pro Phe Ala Ala Ala Ala Ala Ala Ala Ala Leu Gly Gly Ala Asp Ala 
    370                 375                 380                 


Ser Ser Pro Ala Gly Ala Gly Thr Pro Glu Ala Gly Ala Thr Ser Leu 
385                 390                 395                 400 


Val Pro Glu Gly Ala Ala Arg Glu Ser Leu Val Ala Leu Val Ser Thr 
                405                 410                 415     


Ser Asp Arg Asp Ser Gly Ala Asn Gly Gln Val Arg Cys Ala Leu Tyr 
            420                 425                 430         


Gly His Glu His Phe Arg Leu Gln Pro Ala Tyr Ala Gly Ser Tyr Leu 
        435                 440                 445             


Val Val Thr Ala Ala Ser Leu Asp Arg Glu Arg Ile Ala Glu Tyr Asn 
    450                 455                 460                 


Leu Thr Leu Val Ala Glu Asp Arg Gly Ala Pro Pro Leu Arg Thr Val 
465                 470                 475                 480 


Arg Pro Tyr Thr Val Arg Val Gly Asp Glu Asn Asp Asn Ala Pro Leu 
                485                 490                 495     


Phe Thr Arg Pro Val Tyr Glu Val Ser Val Arg Glu Asn Asn Pro Pro 
            500                 505                 510         


Gly Ala Tyr Leu Ala Thr Val Ala Ala Arg Asp Arg Asp Leu Gly Arg 
        515                 520                 525             


Asn Gly Gln Val Thr Tyr Arg Leu Leu Glu Ala Glu Val Gly Arg Ala 
    530                 535                 540                 


Gly Gly Ala Val Ser Thr Tyr Val Ser Val Asp Pro Ala Thr Gly Ala 
545                 550                 555                 560 


Ile Tyr Ala Leu Arg Ser Phe Asp Tyr Glu Thr Leu Arg Gln Leu Asp 
                565                 570                 575     


Val Arg Ile Gln Ala Ser Asp Gly Gly Ser Pro Gln Leu Ser Ser Ser 
            580                 585                 590         


Ala Leu Val Gln Val Arg Val Leu Asp Gln Asn Asp His Ala Pro Val 
        595                 600                 605             


Leu Val His Pro Ala Pro Ala Asn Gly Ser Leu Glu Val Ala Val Pro 
    610                 615                 620                 


Gly Arg Thr Ala Lys Asp Thr Val Val Ala Arg Val Gln Ala Arg Asp 
625                 630                 635                 640 


Ala Asp Glu Gly Ala Asn Gly Glu Leu Ala Phe Glu Leu Gln Gln Gln 
                645                 650                 655     


Glu Pro Arg Glu Ala Phe Ala Ile Gly Arg Arg Thr Gly Glu Ile Leu 
            660                 665                 670         


Leu Thr Gly Asp Leu Ser Gln Glu Pro Pro Gly Arg Val Phe Arg Ala 
        675                 680                 685             


Leu Leu Val Ile Ser Asp Gly Gly Arg Pro Pro Leu Thr Thr Thr Ala 
    690                 695                 700                 


Thr Val Ser Phe Val Val Thr Ala Gly Gly Gly Arg Gly Pro Ala Ala 
705                 710                 715                 720 


Pro Ala Ser Ala Gly Ser Pro Glu Arg Ser Arg Pro Pro Gly Ser Arg 
                725                 730                 735     


Leu Gly Val Ser Gly Ser Val Leu Gln Trp Asp Thr Pro Leu Ile Val 
            740                 745                 750         


Ile Ile Val Leu Ala Gly Ser Cys Thr Leu Leu Leu Ala Ala Ile Ile 
        755                 760                 765             


Ala Ile Ala Thr Thr Cys Asn Arg Arg Lys Lys Glu Pro Tyr Gly Ala 
    770                 775                 780                 


Ser Pro Gly Phe Gly Lys Glu Pro Ala Pro Pro Val Ala Val Trp Lys 
785                 790                 795                 800 


Gly His Ser Phe Asn Thr Ile Ser Gly Arg Glu Ala Glu Lys Phe Ser 
                805                 810                 815     


Gly Lys Asp Ser Gly Lys Gly Asp Ser Asp Phe Asn Asp Ser Asp Ser 
            820                 825                 830         


Asp Ile Ser Gly Asp Ala Leu Lys Lys Asp Leu Ile Asn His Met Gln 
        835                 840                 845             


Ser Gly Leu Trp Ala Cys Thr Ala Glu Cys Lys Ile Leu Gly His Ser 
    850                 855                 860                 


Asp Arg Cys Trp Ser Pro Ser Cys Ser Gly Pro Asn Ala His Pro Ser 
865                 870                 875                 880 


Pro His Pro Pro Ala Gln Met Ser Thr Phe Cys Lys Ser Thr Ser Leu 
                885                 890                 895     


Pro Arg Asp Pro Leu Arg Arg Asp Asn Tyr Tyr Gln Ala Gln Leu Pro 
            900                 905                 910         


Lys Thr Val Gly Leu Gln Ser Val Tyr Glu Lys Val Leu His Arg Asp 
        915                 920                 925             


Tyr Asp Arg Thr Val Thr Leu Leu Ser Pro Pro Arg Pro Gly Arg Leu 
    930                 935                 940                 


Pro Asp Leu Gln Glu Ile Gly Val Pro Leu Tyr Gln Ser Pro Pro Gly 
945                 950                 955                 960 


Arg Tyr Leu Ser Pro Lys Lys Gly Ala Asn Glu Asn Val 
                965                 970             


<210>  3580
<211>  1203
<212>  PRT
<213>  homo sapiens

<400>  3580

Met Asp Leu Arg Asp Phe Tyr Leu Leu Ala Ala Leu Ile Ala Cys Leu 
1               5                   10                  15      


Arg Leu Asp Ser Ala Ile Ala Gln Glu Leu Ile Tyr Thr Ile Arg Glu 
            20                  25                  30          


Glu Leu Pro Glu Asn Val Pro Ile Gly Asn Ile Pro Lys Asp Leu Asn 
        35                  40                  45              


Ile Ser His Ile Asn Ala Ala Thr Gly Thr Ser Ala Ser Leu Val Tyr 
    50                  55                  60                  


Arg Leu Val Ser Lys Ala Gly Asp Ala Pro Leu Val Lys Val Ser Ser 
65                  70                  75                  80  


Ser Thr Gly Glu Ile Phe Thr Thr Ser Asn Arg Ile Asp Arg Glu Lys 
                85                  90                  95      


Leu Cys Ala Gly Ala Ser Tyr Ala Glu Glu Asn Glu Cys Phe Phe Glu 
            100                 105                 110         


Leu Glu Val Val Ile Leu Pro Asn Asp Phe Phe Arg Leu Ile Lys Ile 
        115                 120                 125             


Lys Ile Ile Val Lys Asp Thr Asn Asp Asn Ala Pro Met Phe Pro Ser 
    130                 135                 140                 


Pro Val Ile Asn Ile Ser Ile Pro Glu Asn Thr Leu Ile Asn Ser Arg 
145                 150                 155                 160 


Phe Pro Ile Pro Ser Ala Thr Asp Pro Asp Thr Gly Phe Asn Gly Val 
                165                 170                 175     


Gln His Tyr Glu Leu Leu Asn Gly Gln Ser Val Phe Gly Leu Asp Ile 
            180                 185                 190         


Val Glu Thr Pro Glu Gly Glu Lys Trp Pro Gln Leu Ile Val Gln Gln 
        195                 200                 205             


Asn Leu Asp Arg Glu Gln Lys Asp Thr Tyr Val Met Lys Ile Lys Val 
    210                 215                 220                 


Glu Asp Gly Gly Thr Pro Gln Lys Ser Ser Thr Ala Ile Leu Gln Val 
225                 230                 235                 240 


Thr Val Ser Asp Val Asn Asp Asn Arg Pro Val Phe Lys Glu Gly Gln 
                245                 250                 255     


Val Glu Val His Ile Pro Glu Asn Ala Pro Val Gly Thr Ser Val Ile 
            260                 265                 270         


Gln Leu His Ala Thr Asp Ala Asp Ile Gly Ser Asn Ala Glu Ile Arg 
        275                 280                 285             


Tyr Ile Phe Gly Ala Gln Val Ala Pro Ala Thr Lys Arg Leu Phe Ala 
    290                 295                 300                 


Leu Asn Asn Thr Thr Gly Leu Ile Thr Val Gln Arg Ser Leu Asp Arg 
305                 310                 315                 320 


Glu Glu Thr Ala Ile His Lys Val Thr Val Leu Ala Ser Asp Gly Ser 
                325                 330                 335     


Ser Thr Pro Ala Arg Ala Thr Val Thr Ile Asn Val Thr Asp Val Asn 
            340                 345                 350         


Asp Asn Pro Pro Asn Ile Asp Leu Arg Tyr Ile Ile Ser Pro Ile Asn 
        355                 360                 365             


Gly Thr Val Tyr Leu Ser Glu Lys Asp Pro Val Asn Thr Lys Ile Ala 
    370                 375                 380                 


Leu Ile Thr Val Ser Asp Lys Asp Thr Asp Val Asn Gly Lys Val Ile 
385                 390                 395                 400 


Cys Phe Ile Glu Arg Glu Val Pro Phe His Leu Lys Ala Val Tyr Asp 
                405                 410                 415     


Asn Gln Tyr Leu Leu Glu Thr Ser Ser Leu Leu Asp Tyr Glu Gly Thr 
            420                 425                 430         


Lys Glu Phe Ser Phe Lys Ile Val Ala Ser Asp Ser Gly Lys Pro Ser 
        435                 440                 445             


Leu Asn Gln Thr Ala Leu Val Arg Val Lys Leu Glu Asp Glu Asn Asp 
    450                 455                 460                 


Asn Pro Pro Ile Phe Asn Gln Pro Val Ile Glu Leu Ser Val Ser Glu 
465                 470                 475                 480 


Asn Asn Arg Arg Gly Leu Tyr Leu Thr Thr Ile Ser Ala Thr Asp Glu 
                485                 490                 495     


Asp Ser Gly Lys Asn Ala Asp Ile Val Tyr Gln Leu Gly Pro Asn Ala 
            500                 505                 510         


Ser Phe Phe Asp Leu Asp Arg Lys Thr Gly Val Leu Thr Ala Ser Arg 
        515                 520                 525             


Val Phe Asp Arg Glu Glu Gln Glu Arg Phe Ile Phe Thr Val Thr Ala 
    530                 535                 540                 


Arg Asp Asn Gly Thr Pro Pro Leu Gln Ser Gln Ala Ala Val Ile Val 
545                 550                 555                 560 


Thr Val Leu Asp Glu Asn Asp Asn Ser Pro Lys Phe Thr His Asn His 
                565                 570                 575     


Phe Gln Phe Phe Val Ser Glu Asn Leu Pro Lys Tyr Ser Thr Val Gly 
            580                 585                 590         


Val Ile Thr Val Thr Asp Ala Asp Ala Gly Glu Asn Lys Ala Val Thr 
        595                 600                 605             


Leu Ser Ile Leu Asn Asp Asn Asp Asn Phe Val Leu Asp Pro Tyr Ser 
    610                 615                 620                 


Gly Val Ile Lys Ser Asn Val Ser Phe Asp Arg Glu Gln Gln Ser Ser 
625                 630                 635                 640 


Tyr Thr Phe Asp Val Lys Ala Thr Asp Gly Gly Gln Pro Pro Arg Ser 
                645                 650                 655     


Ser Thr Ala Lys Val Thr Ile Asn Val Met Asp Val Asn Asp Asn Ser 
            660                 665                 670         


Pro Val Val Ile Ser Pro Pro Ser Asn Thr Ser Phe Lys Leu Val Pro 
        675                 680                 685             


Leu Ser Ala Ile Pro Gly Ser Val Val Ala Glu Val Phe Ala Val Asp 
    690                 695                 700                 


Val Asp Thr Gly Met Asn Ala Glu Leu Lys Tyr Thr Ile Val Ser Gly 
705                 710                 715                 720 


Asn Asn Lys Gly Leu Phe Arg Ile Asp Pro Val Thr Gly Asn Ile Thr 
                725                 730                 735     


Leu Glu Glu Lys Pro Ala Pro Thr Asp Val Gly Leu His Arg Leu Val 
            740                 745                 750         


Val Asn Ile Ser Asp Leu Gly Tyr Pro Lys Ser Leu His Thr Leu Val 
        755                 760                 765             


Leu Val Phe Leu Tyr Val Asn Asp Thr Ala Gly Asn Ala Ser Tyr Ile 
    770                 775                 780                 


Tyr Asp Leu Ile Arg Arg Thr Met Glu Thr Pro Leu Asp Arg Asn Ile 
785                 790                 795                 800 


Gly Asp Ser Ser Gln Pro Tyr Gln Asn Glu Asp Tyr Leu Thr Ile Met 
                805                 810                 815     


Ile Ala Ile Ile Ala Gly Ala Met Val Val Ile Val Val Ile Phe Val 
            820                 825                 830         


Thr Val Leu Val Arg Cys Arg His Ala Ser Arg Phe Lys Ala Ala Gln 
        835                 840                 845             


Arg Ser Lys Gln Gly Ala Glu Trp Met Ser Pro Asn Gln Glu Asn Lys 
    850                 855                 860                 


Gln Asn Lys Lys Lys Lys Arg Lys Lys Arg Lys Ser Pro Lys Ser Ser 
865                 870                 875                 880 


Leu Leu Asn Phe Val Thr Ile Glu Glu Ser Lys Pro Asp Asp Ala Val 
                885                 890                 895     


His Glu Pro Ile Asn Gly Thr Ile Ser Leu Pro Ala Glu Leu Glu Glu 
            900                 905                 910         


Gln Ser Ile Gly Arg Phe Asp Trp Gly Pro Ala Pro Pro Thr Thr Phe 
        915                 920                 925             


Lys Pro Asn Ser Pro Asp Leu Ala Lys His Tyr Lys Ser Ala Ser Pro 
    930                 935                 940                 


Gln Pro Ala Phe His Leu Lys Pro Asp Thr Pro Val Ser Val Lys Lys 
945                 950                 955                 960 


His His Val Ile Gln Glu Leu Pro Leu Asp Asn Thr Phe Val Gly Gly 
                965                 970                 975     


Cys Asp Thr Leu Ser Lys Arg Ser Ser Thr Ser Ser Asp His Phe Ser 
            980                 985                 990         


Ala Ser Glu Cys Ser Ser Gln Gly  Gly Phe Lys Thr Lys  Gly Pro Leu 
        995                 1000                 1005             


His Thr  Arg Gln Ser Gln Arg  Arg Val Thr Phe His  Leu Pro Asp 
    1010                 1015                 1020             


Gly Ser  Gln Glu Ser Cys Ser  Asp Ser Gly Leu Gly  Asp His Glu 
    1025                 1030                 1035             


Pro Val  Gly Ser Gly Thr Leu  Ile Ser His Pro Leu  Pro Leu Val 
    1040                 1045                 1050             


Gln Pro  Gln Asp Glu Phe Tyr  Asp Gln Ala Ser Pro  Asp Lys Arg 
    1055                 1060                 1065             


Thr Glu  Ala Asp Gly Asn Ser  Asp Pro Asn Ser Asp  Gly Pro Leu 
    1070                 1075                 1080             


Gly Pro  Arg Gly Leu Ala Glu  Ala Thr Glu Met Cys  Thr Gln Glu 
    1085                 1090                 1095             


Cys Leu  Val Leu Gly His Ser  Asp Asn Cys Trp Met  Pro Pro Gly 
    1100                 1105                 1110             


Leu Gly  Pro Tyr Gln His Pro  Lys Ser Pro Leu Ser  Thr Phe Ala 
    1115                 1120                 1125             


Pro Gln  Lys Glu Trp Val Lys  Lys Asp Lys Leu Val  Asn Gly His 
    1130                 1135                 1140             


Thr Leu  Thr Arg Ala Trp Lys  Glu Asp Ser Asn Arg  Asn Gln Phe 
    1145                 1150                 1155             


Asn Asp  Arg Lys Gln Tyr Gly  Ser Asn Glu Gly His  Phe Asn Asn 
    1160                 1165                 1170             


Gly Ser  His Met Thr Asp Ile  Pro Leu Ala Asn Leu  Lys Ser Tyr 
    1175                 1180                 1185             


Lys Gln  Ala Gly Gly Ala Thr  Glu Ser Pro Lys Glu  His Gln Leu 
    1190                 1195                 1200             


<210>  3581
<211>  1237
<212>  PRT
<213>  homo sapiens

<400>  3581

Met Asp Leu Arg Asp Phe Tyr Leu Leu Ala Ala Leu Ile Ala Cys Leu 
1               5                   10                  15      


Arg Leu Asp Ser Ala Ile Ala Gln Glu Leu Ile Tyr Thr Ile Arg Glu 
            20                  25                  30          


Glu Leu Pro Glu Asn Val Pro Ile Gly Asn Ile Pro Lys Asp Leu Asn 
        35                  40                  45              


Ile Ser His Ile Asn Ala Ala Thr Gly Thr Ser Ala Ser Leu Val Tyr 
    50                  55                  60                  


Arg Leu Val Ser Lys Ala Gly Asp Ala Pro Leu Val Lys Val Ser Ser 
65                  70                  75                  80  


Ser Thr Gly Glu Ile Phe Thr Thr Ser Asn Arg Ile Asp Arg Glu Lys 
                85                  90                  95      


Leu Cys Ala Gly Ala Ser Tyr Ala Glu Glu Asn Glu Cys Phe Phe Glu 
            100                 105                 110         


Leu Glu Val Val Ile Leu Pro Asn Asp Phe Phe Arg Leu Ile Lys Ile 
        115                 120                 125             


Lys Ile Ile Val Lys Asp Thr Asn Asp Asn Ala Pro Met Phe Pro Ser 
    130                 135                 140                 


Pro Val Ile Asn Ile Ser Ile Pro Glu Asn Thr Leu Ile Asn Ser Arg 
145                 150                 155                 160 


Phe Pro Ile Pro Ser Ala Thr Asp Pro Asp Thr Gly Phe Asn Gly Val 
                165                 170                 175     


Gln His Tyr Glu Leu Leu Asn Gly Gln Ser Val Phe Gly Leu Asp Ile 
            180                 185                 190         


Val Glu Thr Pro Glu Gly Glu Lys Trp Pro Gln Leu Ile Val Gln Gln 
        195                 200                 205             


Asn Leu Asp Arg Glu Gln Lys Asp Thr Tyr Val Met Lys Ile Lys Val 
    210                 215                 220                 


Glu Asp Gly Gly Thr Pro Gln Lys Ser Ser Thr Ala Ile Leu Gln Val 
225                 230                 235                 240 


Thr Val Ser Asp Val Asn Asp Asn Arg Pro Val Phe Lys Glu Gly Gln 
                245                 250                 255     


Val Glu Val His Ile Pro Glu Asn Ala Pro Val Gly Thr Ser Val Ile 
            260                 265                 270         


Gln Leu His Ala Thr Asp Ala Asp Ile Gly Ser Asn Ala Glu Ile Arg 
        275                 280                 285             


Tyr Ile Phe Gly Ala Gln Val Ala Pro Ala Thr Lys Arg Leu Phe Ala 
    290                 295                 300                 


Leu Asn Asn Thr Thr Gly Leu Ile Thr Val Gln Arg Ser Leu Asp Arg 
305                 310                 315                 320 


Glu Glu Thr Ala Ile His Lys Val Thr Val Leu Ala Ser Asp Gly Ser 
                325                 330                 335     


Ser Thr Pro Ala Arg Ala Thr Val Thr Ile Asn Val Thr Asp Val Asn 
            340                 345                 350         


Asp Asn Pro Pro Asn Ile Asp Leu Arg Tyr Ile Ile Ser Pro Ile Asn 
        355                 360                 365             


Gly Thr Val Tyr Leu Ser Glu Lys Asp Pro Val Asn Thr Lys Ile Ala 
    370                 375                 380                 


Leu Ile Thr Val Ser Asp Lys Asp Thr Asp Val Asn Gly Lys Val Ile 
385                 390                 395                 400 


Cys Phe Ile Glu Arg Glu Val Pro Phe His Leu Lys Ala Val Tyr Asp 
                405                 410                 415     


Asn Gln Tyr Leu Leu Glu Thr Ser Ser Leu Leu Asp Tyr Glu Gly Thr 
            420                 425                 430         


Lys Glu Phe Ser Phe Lys Ile Val Ala Ser Asp Ser Gly Lys Pro Ser 
        435                 440                 445             


Leu Asn Gln Thr Ala Leu Val Arg Val Lys Leu Glu Asp Glu Asn Asp 
    450                 455                 460                 


Asn Pro Pro Ile Phe Asn Gln Pro Val Ile Glu Leu Ser Val Ser Glu 
465                 470                 475                 480 


Asn Asn Arg Arg Gly Leu Tyr Leu Thr Thr Ile Ser Ala Thr Asp Glu 
                485                 490                 495     


Asp Ser Gly Lys Asn Ala Asp Ile Val Tyr Gln Leu Gly Pro Asn Ala 
            500                 505                 510         


Ser Phe Phe Asp Leu Asp Arg Lys Thr Gly Val Leu Thr Ala Ser Arg 
        515                 520                 525             


Val Phe Asp Arg Glu Glu Gln Glu Arg Phe Ile Phe Thr Val Thr Ala 
    530                 535                 540                 


Arg Asp Asn Gly Thr Pro Pro Leu Gln Ser Gln Ala Ala Val Ile Val 
545                 550                 555                 560 


Thr Val Leu Asp Glu Asn Asp Asn Ser Pro Lys Phe Thr His Asn His 
                565                 570                 575     


Phe Gln Phe Phe Val Ser Glu Asn Leu Pro Lys Tyr Ser Thr Val Gly 
            580                 585                 590         


Val Ile Thr Val Thr Asp Ala Asp Ala Gly Glu Asn Lys Ala Val Thr 
        595                 600                 605             


Leu Ser Ile Leu Asn Asp Asn Asp Asn Phe Val Leu Asp Pro Tyr Ser 
    610                 615                 620                 


Gly Val Ile Lys Ser Asn Val Ser Phe Asp Arg Glu Gln Gln Ser Ser 
625                 630                 635                 640 


Tyr Thr Phe Asp Val Lys Ala Thr Asp Gly Gly Gln Pro Pro Arg Ser 
                645                 650                 655     


Ser Thr Ala Lys Val Thr Ile Asn Val Met Asp Val Asn Asp Asn Ser 
            660                 665                 670         


Pro Val Val Ile Ser Pro Pro Ser Asn Thr Ser Phe Lys Leu Val Pro 
        675                 680                 685             


Leu Ser Ala Ile Pro Gly Ser Val Val Ala Glu Val Phe Ala Val Asp 
    690                 695                 700                 


Val Asp Thr Gly Met Asn Ala Glu Leu Lys Tyr Thr Ile Val Ser Gly 
705                 710                 715                 720 


Asn Asn Lys Gly Leu Phe Arg Ile Asp Pro Val Thr Gly Asn Ile Thr 
                725                 730                 735     


Leu Glu Glu Lys Pro Ala Pro Thr Asp Val Gly Leu His Arg Leu Val 
            740                 745                 750         


Val Asn Ile Ser Asp Leu Gly Tyr Pro Lys Ser Leu His Thr Leu Val 
        755                 760                 765             


Leu Val Phe Leu Tyr Val Asn Asp Thr Ala Gly Asn Ala Ser Tyr Ile 
    770                 775                 780                 


Tyr Asp Leu Ile Arg Arg Thr Met Glu Thr Pro Leu Asp Arg Asn Ile 
785                 790                 795                 800 


Gly Asp Ser Ser Gln Pro Tyr Gln Asn Glu Asp Tyr Leu Thr Ile Met 
                805                 810                 815     


Ile Ala Ile Ile Ala Gly Ala Met Val Val Ile Val Val Ile Phe Val 
            820                 825                 830         


Thr Val Leu Val Arg Cys Arg His Ala Ser Arg Phe Lys Ala Ala Gln 
        835                 840                 845             


Arg Ser Lys Gln Gly Ala Glu Trp Met Ser Pro Asn Gln Glu Asn Lys 
    850                 855                 860                 


Gln Asn Lys Lys Lys Lys Arg Lys Lys Arg Lys Ser Pro Lys Ser Ser 
865                 870                 875                 880 


Leu Leu Asn Phe Val Thr Ile Glu Glu Ser Lys Pro Asp Asp Ala Val 
                885                 890                 895     


His Glu Pro Ile Asn Gly Thr Ile Ser Leu Pro Ala Glu Leu Glu Glu 
            900                 905                 910         


Gln Ser Ile Gly Arg Phe Asp Trp Gly Pro Ala Pro Pro Thr Thr Phe 
        915                 920                 925             


Lys Pro Asn Ser Pro Asp Leu Ala Lys His Tyr Lys Ser Ala Ser Pro 
    930                 935                 940                 


Gln Pro Ala Phe His Leu Lys Pro Asp Thr Pro Val Ser Val Lys Lys 
945                 950                 955                 960 


His His Val Ile Gln Glu Leu Pro Leu Asp Asn Thr Phe Val Gly Gly 
                965                 970                 975     


Cys Asp Thr Leu Ser Lys Arg Ser Ser Thr Ser Ser Asp His Phe Ser 
            980                 985                 990         


Ala Ser Glu Cys Ser Ser Gln Gly  Gly Phe Lys Thr Lys  Gly Pro Leu 
        995                 1000                 1005             


His Thr  Arg Gln Cys Asn Ser  His Ser Lys Ser Asp  Asn Ile Pro 
    1010                 1015                 1020             


Val Thr  Pro Gln Lys Cys Pro  Ser Ser Thr Gly Phe  His Ile Gln 
    1025                 1030                 1035             


Glu Asn  Glu Glu Ser His Tyr  Glu Ser Gln Arg Arg  Val Thr Phe 
    1040                 1045                 1050             


His Leu  Pro Asp Gly Ser Gln  Glu Ser Cys Ser Asp  Ser Gly Leu 
    1055                 1060                 1065             


Gly Asp  His Glu Pro Val Gly  Ser Gly Thr Leu Ile  Ser His Pro 
    1070                 1075                 1080             


Leu Pro  Leu Val Gln Pro Gln  Asp Glu Phe Tyr Asp  Gln Ala Ser 
    1085                 1090                 1095             


Pro Asp  Lys Arg Thr Glu Ala  Asp Gly Asn Ser Asp  Pro Asn Ser 
    1100                 1105                 1110             


Asp Gly  Pro Leu Gly Pro Arg  Gly Leu Ala Glu Ala  Thr Glu Met 
    1115                 1120                 1125             


Cys Thr  Gln Glu Cys Leu Val  Leu Gly His Ser Asp  Asn Cys Trp 
    1130                 1135                 1140             


Met Pro  Pro Gly Leu Gly Pro  Tyr Gln His Pro Lys  Ser Pro Leu 
    1145                 1150                 1155             


Ser Thr  Phe Ala Pro Gln Lys  Glu Trp Val Lys Lys  Asp Lys Leu 
    1160                 1165                 1170             


Val Asn  Gly His Thr Leu Thr  Arg Ala Trp Lys Glu  Asp Ser Asn 
    1175                 1180                 1185             


Arg Asn  Gln Phe Asn Asp Arg  Lys Gln Tyr Gly Ser  Asn Glu Gly 
    1190                 1195                 1200             


His Phe  Asn Asn Gly Ser His  Met Thr Asp Ile Pro  Leu Ala Asn 
    1205                 1210                 1215             


Leu Lys  Ser Tyr Lys Gln Ala  Gly Gly Ala Thr Glu  Ser Pro Lys 
    1220                 1225                 1230             


Glu His  Gln Leu 
    1235         


<210>  3582
<211>  4097
<212>  PRT
<213>  homo sapiens

<400>  3582

Met Ala Gly Ser Gly Ala Gly Val Arg Cys Ser Leu Leu Arg Leu Gln 
1               5                   10                  15      


Glu Thr Leu Ser Ala Ala Asp Arg Cys Gly Ala Ala Leu Ala Gly His 
            20                  25                  30          


Gln Leu Ile Arg Gly Leu Gly Gln Glu Cys Val Leu Ser Ser Ser Pro 
        35                  40                  45              


Ala Val Leu Ala Leu Gln Thr Ser Leu Val Phe Ser Arg Asp Phe Gly 
    50                  55                  60                  


Leu Leu Val Phe Val Arg Lys Ser Leu Asn Ser Ile Glu Phe Arg Glu 
65                  70                  75                  80  


Cys Arg Glu Glu Ile Leu Lys Phe Leu Cys Ile Phe Leu Glu Lys Met 
                85                  90                  95      


Gly Gln Lys Ile Ala Pro Tyr Ser Val Glu Ile Lys Asn Thr Cys Thr 
            100                 105                 110         


Ser Val Tyr Thr Lys Asp Arg Ala Ala Lys Cys Lys Ile Pro Ala Leu 
        115                 120                 125             


Asp Leu Leu Ile Lys Leu Leu Gln Thr Phe Arg Ser Ser Arg Leu Met 
    130                 135                 140                 


Asp Glu Phe Lys Ile Gly Glu Leu Phe Ser Lys Phe Tyr Gly Glu Leu 
145                 150                 155                 160 


Ala Leu Lys Lys Lys Ile Pro Asp Thr Val Leu Glu Lys Val Tyr Glu 
                165                 170                 175     


Leu Leu Gly Leu Leu Gly Glu Val His Pro Ser Glu Met Ile Asn Asn 
            180                 185                 190         


Ala Glu Asn Leu Phe Arg Ala Phe Leu Gly Glu Leu Lys Thr Gln Met 
        195                 200                 205             


Thr Ser Ala Val Arg Glu Pro Lys Leu Pro Val Leu Ala Gly Cys Leu 
    210                 215                 220                 


Lys Gly Leu Ser Ser Leu Leu Cys Asn Phe Thr Lys Ser Met Glu Glu 
225                 230                 235                 240 


Asp Pro Gln Thr Ser Arg Glu Ile Phe Asn Phe Val Leu Lys Ala Ile 
                245                 250                 255     


Arg Pro Gln Ile Asp Leu Lys Arg Tyr Ala Val Pro Ser Ala Gly Leu 
            260                 265                 270         


Arg Leu Phe Ala Leu His Ala Ser Gln Phe Ser Thr Cys Leu Leu Asp 
        275                 280                 285             


Asn Tyr Val Ser Leu Phe Glu Val Leu Leu Lys Trp Cys Ala His Thr 
    290                 295                 300                 


Asn Val Glu Leu Lys Lys Ala Ala Leu Ser Ala Leu Glu Ser Phe Leu 
305                 310                 315                 320 


Lys Gln Val Ser Asn Met Val Ala Lys Asn Ala Glu Met His Lys Asn 
                325                 330                 335     


Lys Leu Gln Tyr Phe Met Glu Gln Phe Tyr Gly Ile Ile Arg Asn Val 
            340                 345                 350         


Asp Ser Asn Asn Lys Glu Leu Ser Ile Ala Ile Arg Gly Tyr Gly Leu 
        355                 360                 365             


Phe Ala Gly Pro Cys Lys Val Ile Asn Ala Lys Asp Val Asp Phe Met 
    370                 375                 380                 


Tyr Val Glu Leu Ile Gln Arg Cys Lys Gln Met Phe Leu Thr Gln Thr 
385                 390                 395                 400 


Asp Thr Gly Asp Asp Arg Val Tyr Gln Met Pro Ser Phe Leu Gln Ser 
                405                 410                 415     


Val Ala Ser Val Leu Leu Tyr Leu Asp Thr Val Pro Glu Val Tyr Thr 
            420                 425                 430         


Pro Val Leu Glu His Leu Val Val Met Gln Ile Asp Ser Phe Pro Gln 
        435                 440                 445             


Tyr Ser Pro Lys Met Gln Leu Val Cys Cys Arg Ala Ile Val Lys Val 
    450                 455                 460                 


Phe Leu Ala Leu Ala Ala Lys Gly Pro Val Leu Arg Asn Cys Ile Ser 
465                 470                 475                 480 


Thr Val Val His Gln Gly Leu Ile Arg Ile Cys Ser Lys Pro Val Val 
                485                 490                 495     


Leu Pro Lys Gly Pro Glu Ser Glu Ser Glu Asp His Arg Ala Ser Gly 
            500                 505                 510         


Glu Val Arg Thr Gly Lys Trp Lys Val Pro Thr Tyr Lys Asp Tyr Val 
        515                 520                 525             


Asp Leu Phe Arg His Leu Leu Ser Ser Asp Gln Met Met Asp Ser Ile 
    530                 535                 540                 


Leu Ala Asp Glu Ala Phe Phe Ser Val Asn Ser Ser Ser Glu Ser Leu 
545                 550                 555                 560 


Asn His Leu Leu Tyr Asp Glu Phe Val Lys Ser Val Leu Lys Ile Val 
                565                 570                 575     


Glu Lys Leu Asp Leu Thr Leu Glu Ile Gln Thr Val Gly Glu Gln Glu 
            580                 585                 590         


Asn Gly Asp Glu Ala Pro Gly Val Trp Met Ile Pro Thr Ser Asp Pro 
        595                 600                 605             


Ala Ala Asn Leu His Pro Ala Lys Pro Lys Asp Phe Ser Ala Phe Ile 
    610                 615                 620                 


Asn Leu Val Glu Phe Cys Arg Glu Ile Leu Pro Glu Lys Gln Ala Glu 
625                 630                 635                 640 


Phe Phe Glu Pro Trp Val Tyr Ser Phe Ser Tyr Glu Leu Ile Leu Gln 
                645                 650                 655     


Ser Thr Arg Leu Pro Leu Ile Ser Gly Phe Tyr Lys Leu Leu Ser Ile 
            660                 665                 670         


Thr Val Arg Asn Ala Lys Lys Ile Lys Tyr Phe Glu Gly Val Ser Pro 
        675                 680                 685             


Lys Ser Leu Lys His Ser Pro Glu Asp Pro Glu Lys Tyr Ser Cys Phe 
    690                 695                 700                 


Ala Leu Phe Val Lys Phe Gly Lys Glu Val Ala Val Lys Met Lys Gln 
705                 710                 715                 720 


Tyr Lys Asp Glu Leu Leu Ala Ser Cys Leu Thr Phe Leu Leu Ser Leu 
                725                 730                 735     


Pro His Asn Ile Ile Glu Leu Asp Val Arg Ala Tyr Val Pro Ala Leu 
            740                 745                 750         


Gln Met Ala Phe Lys Leu Gly Leu Ser Tyr Thr Pro Leu Ala Glu Val 
        755                 760                 765             


Gly Leu Asn Ala Leu Glu Glu Trp Ser Ile Tyr Ile Asp Arg His Val 
    770                 775                 780                 


Met Gln Pro Tyr Tyr Lys Asp Ile Leu Pro Cys Leu Asp Gly Tyr Leu 
785                 790                 795                 800 


Lys Thr Ser Ala Leu Ser Asp Glu Thr Lys Asn Asn Trp Glu Val Ser 
                805                 810                 815     


Ala Leu Ser Arg Ala Ala Gln Lys Gly Phe Asn Lys Val Val Leu Lys 
            820                 825                 830         


His Leu Lys Lys Thr Lys Asn Leu Ser Ser Asn Glu Ala Ile Ser Leu 
        835                 840                 845             


Glu Glu Ile Arg Ile Arg Val Val Gln Met Leu Gly Ser Leu Gly Gly 
    850                 855                 860                 


Gln Ile Asn Lys Asn Leu Leu Thr Val Thr Ser Ser Asp Glu Met Met 
865                 870                 875                 880 


Lys Ser Tyr Val Ala Trp Asp Arg Glu Lys Arg Leu Ser Phe Ala Val 
                885                 890                 895     


Pro Phe Arg Glu Met Lys Pro Val Ile Phe Leu Asp Val Phe Leu Pro 
            900                 905                 910         


Arg Val Thr Glu Leu Ala Leu Thr Ala Ser Asp Arg Gln Thr Lys Val 
        915                 920                 925             


Ala Ala Cys Glu Leu Leu His Ser Met Val Met Phe Met Leu Gly Lys 
    930                 935                 940                 


Ala Thr Gln Met Pro Glu Gly Gly Gln Gly Ala Pro Pro Met Tyr Gln 
945                 950                 955                 960 


Leu Tyr Lys Arg Thr Phe Pro Val Leu Leu Arg Leu Ala Cys Asp Val 
                965                 970                 975     


Asp Gln Val Thr Arg Gln Leu Tyr Glu Pro Leu Val Met Gln Leu Ile 
            980                 985                 990         


His Trp Phe Thr Asn Asn Lys Lys  Phe Glu Ser Gln Asp  Thr Val Ala 
        995                 1000                 1005             


Leu Leu  Glu Ala Ile Leu Asp  Gly Ile Val Asp Pro  Val Asp Ser 
    1010                 1015                 1020             


Thr Leu  Arg Asp Phe Cys Gly  Arg Cys Ile Arg Glu  Phe Leu Lys 
    1025                 1030                 1035             


Trp Ser  Ile Lys Gln Ile Thr  Pro Gln Gln Gln Glu  Lys Ser Pro 
    1040                 1045                 1050             


Val Asn  Thr Lys Ser Leu Phe  Lys Arg Leu Tyr Ser  Leu Ala Leu 
    1055                 1060                 1065             


His Pro  Asn Ala Phe Lys Arg  Leu Gly Ala Ser Leu  Ala Phe Asn 
    1070                 1075                 1080             


Asn Ile  Tyr Arg Glu Phe Arg  Glu Glu Glu Ser Leu  Val Glu Gln 
    1085                 1090                 1095             


Phe Val  Phe Glu Ala Leu Val  Ile Tyr Met Glu Ser  Leu Ala Leu 
    1100                 1105                 1110             


Ala His  Ala Asp Glu Lys Ser  Leu Gly Thr Ile Gln  Gln Cys Cys 
    1115                 1120                 1125             


Asp Ala  Ile Asp His Leu Cys  Arg Ile Ile Glu Lys  Lys His Val 
    1130                 1135                 1140             


Ser Leu  Asn Lys Ala Lys Lys  Arg Arg Leu Pro Arg  Gly Phe Pro 
    1145                 1150                 1155             


Pro Ser  Ala Ser Leu Cys Leu  Leu Asp Leu Val Lys  Trp Leu Leu 
    1160                 1165                 1170             


Ala His  Cys Gly Arg Pro Gln  Thr Glu Cys Arg His  Lys Ser Ile 
    1175                 1180                 1185             


Glu Leu  Phe Tyr Lys Phe Val  Pro Leu Leu Pro Gly  Asn Arg Ser 
    1190                 1195                 1200             


Pro Asn  Leu Trp Leu Lys Asp  Val Leu Lys Glu Glu  Gly Val Ser 
    1205                 1210                 1215             


Phe Leu  Ile Asn Thr Phe Glu  Gly Gly Gly Cys Gly  Gln Pro Ser 
    1220                 1225                 1230             


Gly Ile  Leu Ala Gln Pro Thr  Leu Leu Tyr Leu Arg  Gly Pro Phe 
    1235                 1240                 1245             


Ser Leu  Gln Ala Thr Leu Cys  Trp Leu Asp Leu Leu  Leu Ala Ala 
    1250                 1255                 1260             


Leu Glu  Cys Tyr Asn Thr Phe  Ile Gly Glu Arg Thr  Val Gly Ala 
    1265                 1270                 1275             


Leu Gln  Val Leu Gly Thr Glu  Ala Gln Ser Ser Leu  Leu Lys Ala 
    1280                 1285                 1290             


Val Ala  Phe Phe Leu Glu Ser  Ile Ala Met His Asp  Ile Ile Ala 
    1295                 1300                 1305             


Ala Glu  Lys Cys Phe Gly Thr  Gly Ala Ala Gly Asn  Arg Thr Ser 
    1310                 1315                 1320             


Pro Gln  Glu Gly Glu Arg Tyr  Asn Tyr Ser Lys Cys  Thr Val Val 
    1325                 1330                 1335             


Val Arg  Ile Met Glu Phe Thr  Thr Thr Leu Leu Asn  Thr Ser Pro 
    1340                 1345                 1350             


Glu Gly  Trp Lys Leu Leu Lys  Lys Asp Leu Cys Asn  Thr His Leu 
    1355                 1360                 1365             


Met Arg  Val Leu Val Gln Thr  Leu Cys Glu Pro Ala  Ser Ile Gly 
    1370                 1375                 1380             


Phe Asn  Ile Gly Asp Val Gln  Val Met Ala His Leu  Pro Asp Val 
    1385                 1390                 1395             


Cys Val  Asn Leu Met Lys Ala  Leu Lys Met Ser Pro  Tyr Lys Asp 
    1400                 1405                 1410             


Ile Leu  Glu Thr His Leu Arg  Glu Lys Ile Thr Ala  Gln Ser Ile 
    1415                 1420                 1425             


Glu Glu  Leu Cys Ala Val Asn  Leu Tyr Gly Pro Asp  Ala Gln Val 
    1430                 1435                 1440             


Asp Arg  Ser Arg Leu Ala Ala  Val Val Ser Ala Cys  Lys Gln Leu 
    1445                 1450                 1455             


His Arg  Ala Gly Leu Leu His  Asn Ile Leu Pro Ser  Gln Ser Thr 
    1460                 1465                 1470             


Asp Leu  His His Ser Val Gly  Thr Glu Leu Leu Ser  Leu Val Tyr 
    1475                 1480                 1485             


Lys Gly  Ile Ala Pro Gly Asp  Glu Arg Gln Cys Leu  Pro Ser Leu 
    1490                 1495                 1500             


Asp Leu  Ser Cys Lys Gln Leu  Ala Ser Gly Leu Leu  Glu Leu Ala 
    1505                 1510                 1515             


Phe Ala  Phe Gly Gly Leu Cys  Glu Arg Leu Val Ser  Leu Leu Leu 
    1520                 1525                 1530             


Asn Pro  Ala Val Leu Ser Thr  Ala Ser Leu Gly Ser  Ser Gln Gly 
    1535                 1540                 1545             


Ser Val  Ile His Phe Ser His  Gly Glu Tyr Phe Tyr  Ser Leu Phe 
    1550                 1555                 1560             


Ser Glu  Thr Ile Asn Thr Glu  Leu Leu Lys Asn Leu  Asp Leu Ala 
    1565                 1570                 1575             


Val Leu  Glu Leu Met Gln Ser  Ser Val Asp Asn Thr  Lys Met Val 
    1580                 1585                 1590             


Ser Ala  Val Leu Asn Gly Met  Leu Asp Gln Ser Phe  Arg Glu Arg 
    1595                 1600                 1605             


Ala Asn  Gln Lys His Gln Gly  Leu Lys Leu Ala Thr  Thr Ile Leu 
    1610                 1615                 1620             


Gln His  Trp Lys Lys Cys Asp  Ser Trp Trp Ala Lys  Asp Ser Pro 
    1625                 1630                 1635             


Leu Glu  Thr Lys Met Ala Val  Leu Ala Leu Leu Ala  Lys Ile Leu 
    1640                 1645                 1650             


Gln Ile  Asp Ser Ser Val Ser  Phe Asn Thr Ser His  Gly Ser Phe 
    1655                 1660                 1665             


Pro Glu  Val Phe Thr Thr Tyr  Ile Ser Leu Leu Ala  Asp Thr Lys 
    1670                 1675                 1680             


Leu Asp  Leu His Leu Lys Gly  Gln Ala Val Thr Leu  Leu Pro Phe 
    1685                 1690                 1695             


Phe Thr  Ser Leu Thr Gly Gly  Ser Leu Glu Glu Leu  Arg Arg Val 
    1700                 1705                 1710             


Leu Glu  Gln Leu Ile Val Ala  His Phe Pro Met Gln  Ser Arg Glu 
    1715                 1720                 1725             


Phe Pro  Pro Gly Thr Pro Arg  Phe Asn Asn Tyr Val  Asp Cys Met 
    1730                 1735                 1740             


Lys Lys  Phe Leu Asp Ala Leu  Glu Leu Ser Gln Ser  Pro Met Leu 
    1745                 1750                 1755             


Leu Glu  Leu Met Thr Glu Val  Leu Cys Arg Glu Gln  Gln His Val 
    1760                 1765                 1770             


Met Glu  Glu Leu Phe Gln Ser  Ser Phe Arg Arg Ile  Ala Arg Arg 
    1775                 1780                 1785             


Gly Ser  Cys Val Thr Gln Val  Gly Leu Leu Glu Ser  Val Tyr Glu 
    1790                 1795                 1800             


Met Phe  Arg Lys Asp Asp Pro  Arg Leu Ser Phe Thr  Arg Gln Ser 
    1805                 1810                 1815             


Phe Val  Asp Arg Ser Leu Leu  Thr Leu Leu Trp His  Cys Ser Leu 
    1820                 1825                 1830             


Asp Ala  Leu Arg Glu Phe Phe  Ser Thr Ile Val Val  Asp Ala Ile 
    1835                 1840                 1845             


Asp Val  Leu Lys Ser Arg Phe  Thr Lys Leu Asn Glu  Ser Thr Phe 
    1850                 1855                 1860             


Asp Thr  Gln Ile Thr Lys Lys  Met Gly Tyr Tyr Lys  Ile Leu Asp 
    1865                 1870                 1875             


Val Met  Tyr Ser Arg Leu Pro  Lys Asp Asp Val His  Ala Lys Glu 
    1880                 1885                 1890             


Ser Lys  Ile Asn Gln Val Phe  His Gly Ser Cys Ile  Thr Glu Gly 
    1895                 1900                 1905             


Asn Glu  Leu Thr Lys Thr Leu  Ile Lys Leu Cys Tyr  Asp Ala Phe 
    1910                 1915                 1920             


Thr Glu  Asn Met Ala Gly Glu  Asn Gln Leu Leu Glu  Arg Arg Arg 
    1925                 1930                 1935             


Leu Tyr  His Cys Ala Ala Tyr  Asn Cys Ala Ile Ser  Val Ile Cys 
    1940                 1945                 1950             


Cys Val  Phe Asn Glu Leu Lys  Phe Tyr Gln Gly Phe  Leu Phe Ser 
    1955                 1960                 1965             


Glu Lys  Pro Glu Lys Asn Leu  Leu Ile Phe Glu Asn  Leu Ile Asp 
    1970                 1975                 1980             


Leu Lys  Arg Arg Tyr Asn Phe  Pro Val Glu Val Glu  Val Pro Met 
    1985                 1990                 1995             


Glu Arg  Lys Lys Lys Tyr Ile  Glu Ile Arg Lys Glu  Ala Arg Glu 
    2000                 2005                 2010             


Ala Ala  Asn Gly Asp Ser Asp  Gly Pro Ser Tyr Met  Ser Ser Leu 
    2015                 2020                 2025             


Ser Tyr  Leu Ala Asp Ser Thr  Leu Ser Glu Glu Met  Ser Gln Phe 
    2030                 2035                 2040             


Asp Phe  Ser Thr Gly Val Gln  Ser Tyr Ser Tyr Ser  Ser Gln Asp 
    2045                 2050                 2055             


Pro Arg  Pro Ala Thr Gly Arg  Phe Arg Arg Arg Glu  Gln Arg Asp 
    2060                 2065                 2070             


Pro Thr  Val His Asp Asp Val  Leu Glu Leu Glu Met  Asp Glu Leu 
    2075                 2080                 2085             


Asn Arg  His Glu Cys Met Ala  Pro Leu Thr Ala Leu  Val Lys His 
    2090                 2095                 2100             


Met His  Arg Ser Leu Gly Pro  Pro Gln Gly Glu Glu  Asp Ser Val 
    2105                 2110                 2115             


Pro Arg  Asp Leu Pro Ser Trp  Met Lys Phe Leu His  Gly Lys Leu 
    2120                 2125                 2130             


Gly Asn  Pro Ile Val Pro Leu  Asn Ile Arg Leu Phe  Leu Ala Lys 
    2135                 2140                 2145             


Leu Val  Ile Asn Thr Glu Glu  Val Phe Arg Pro Tyr  Ala Lys His 
    2150                 2155                 2160             


Trp Leu  Ser Pro Leu Leu Gln  Leu Ala Ala Ser Glu  Asn Asn Gly 
    2165                 2170                 2175             


Gly Glu  Gly Ile His Tyr Met  Val Val Glu Ile Val  Ala Thr Ile 
    2180                 2185                 2190             


Leu Ser  Trp Thr Gly Leu Ala  Thr Pro Thr Gly Val  Pro Lys Asp 
    2195                 2200                 2205             


Glu Val  Leu Ala Asn Arg Leu  Leu Asn Phe Leu Met  Lys His Val 
    2210                 2215                 2220             


Phe His  Pro Lys Arg Ala Val  Phe Arg His Asn Leu  Glu Ile Ile 
    2225                 2230                 2235             


Lys Thr  Leu Val Glu Cys Trp  Lys Asp Cys Leu Ser  Ile Pro Tyr 
    2240                 2245                 2250             


Arg Leu  Ile Phe Glu Lys Phe  Ser Gly Lys Asp Pro  Asn Ser Lys 
    2255                 2260                 2265             


Asp Asn  Ser Val Gly Ile Gln  Leu Leu Gly Ile Val  Met Ala Asn 
    2270                 2275                 2280             


Asp Leu  Pro Pro Tyr Asp Pro  Gln Cys Gly Ile Gln  Ser Ser Glu 
    2285                 2290                 2295             


Tyr Phe  Gln Ala Leu Val Asn  Asn Met Ser Phe Val  Arg Tyr Lys 
    2300                 2305                 2310             


Glu Val  Tyr Ala Ala Ala Ala  Glu Val Leu Gly Leu  Ile Leu Arg 
    2315                 2320                 2325             


Tyr Val  Met Glu Arg Lys Asn  Ile Leu Glu Glu Ser  Leu Cys Glu 
    2330                 2335                 2340             


Leu Val  Ala Lys Gln Leu Lys  Gln His Gln Asn Thr  Met Glu Asp 
    2345                 2350                 2355             


Lys Phe  Ile Val Cys Leu Asn  Lys Val Thr Lys Ser  Phe Pro Pro 
    2360                 2365                 2370             


Leu Ala  Asp Arg Phe Met Asn  Ala Val Phe Phe Leu  Leu Pro Lys 
    2375                 2380                 2385             


Phe His  Gly Val Leu Lys Thr  Leu Cys Leu Glu Val  Val Leu Cys 
    2390                 2395                 2400             


Arg Val  Glu Gly Met Thr Glu  Leu Tyr Phe Gln Leu  Lys Ser Lys 
    2405                 2410                 2415             


Asp Phe  Val Gln Val Met Arg  His Arg Asp Asp Glu  Arg Gln Lys 
    2420                 2425                 2430             


Val Cys  Leu Asp Ile Ile Tyr  Lys Met Met Pro Lys  Leu Lys Pro 
    2435                 2440                 2445             


Val Glu  Leu Arg Glu Leu Leu  Asn Pro Val Val Glu  Phe Val Ser 
    2450                 2455                 2460             


His Pro  Ser Thr Thr Cys Arg  Glu Gln Met Tyr Asn  Ile Leu Met 
    2465                 2470                 2475             


Trp Ile  His Asp Asn Tyr Arg  Asp Pro Glu Ser Glu  Thr Asp Asn 
    2480                 2485                 2490             


Asp Ser  Gln Glu Ile Phe Lys  Leu Ala Lys Asp Val  Leu Ile Gln 
    2495                 2500                 2505             


Gly Leu  Ile Asp Glu Asn Pro  Gly Leu Gln Leu Ile  Ile Arg Asn 
    2510                 2515                 2520             


Phe Trp  Ser His Glu Thr Arg  Leu Pro Ser Asn Thr  Leu Asp Arg 
    2525                 2530                 2535             


Leu Leu  Ala Leu Asn Ser Leu  Tyr Ser Pro Lys Ile  Glu Val His 
    2540                 2545                 2550             


Phe Leu  Ser Leu Ala Thr Asn  Phe Leu Leu Glu Met  Thr Ser Met 
    2555                 2560                 2565             


Ser Pro  Asp Tyr Pro Asn Pro  Met Phe Glu His Pro  Leu Ser Glu 
    2570                 2575                 2580             


Cys Glu  Phe Gln Glu Tyr Thr  Ile Asp Ser Asp Trp  Arg Phe Arg 
    2585                 2590                 2595             


Ser Thr  Val Leu Thr Pro Met  Phe Val Glu Thr Gln  Ala Ser Gln 
    2600                 2605                 2610             


Gly Thr  Leu Gln Thr Arg Thr  Gln Glu Gly Ser Leu  Ser Ala Arg 
    2615                 2620                 2625             


Trp Pro  Val Ala Gly Gln Ile  Arg Ala Thr Gln Gln  Gln His Asp 
    2630                 2635                 2640             


Phe Thr  Leu Thr Gln Thr Ala  Asp Gly Arg Ser Ser  Phe Asp Trp 
    2645                 2650                 2655             


Leu Thr  Gly Ser Ser Thr Asp  Pro Leu Val Asp His  Thr Ser Pro 
    2660                 2665                 2670             


Ser Ser  Asp Ser Leu Leu Phe  Ala His Lys Arg Ser  Glu Arg Leu 
    2675                 2680                 2685             


Gln Arg  Ala Pro Leu Lys Ser  Val Gly Pro Asp Phe  Gly Lys Lys 
    2690                 2695                 2700             


Arg Leu  Gly Leu Pro Gly Asp  Glu Val Asp Asn Lys  Val Lys Gly 
    2705                 2710                 2715             


Ala Ala  Gly Arg Thr Asp Leu  Leu Arg Leu Arg Arg  Arg Phe Met 
    2720                 2725                 2730             


Arg Asp  Gln Glu Lys Leu Ser  Leu Met Tyr Ala Arg  Lys Gly Val 
    2735                 2740                 2745             


Ala Glu  Gln Lys Arg Glu Lys  Glu Ile Lys Ser Glu  Leu Lys Met 
    2750                 2755                 2760             


Lys Gln  Asp Ala Gln Val Val  Leu Tyr Arg Ser Tyr  Arg His Gly 
    2765                 2770                 2775             


Asp Leu  Pro Asp Ile Gln Ile  Lys His Ser Ser Leu  Ile Thr Pro 
    2780                 2785                 2790             


Leu Gln  Ala Val Ala Gln Arg  Asp Pro Ile Ile Ala  Lys Gln Leu 
    2795                 2800                 2805             


Phe Ser  Ser Leu Phe Ser Gly  Ile Leu Lys Glu Met  Asp Lys Phe 
    2810                 2815                 2820             


Lys Thr  Leu Ser Glu Lys Asn  Asn Ile Thr Gln Lys  Leu Leu Gln 
    2825                 2830                 2835             


Asp Phe  Asn Arg Phe Leu Asn  Thr Thr Phe Ser Phe  Phe Pro Pro 
    2840                 2845                 2850             


Phe Val  Ser Cys Ile Gln Asp  Ile Ser Cys Gln His  Ala Ala Leu 
    2855                 2860                 2865             


Leu Ser  Leu Asp Pro Ala Ala  Val Ser Ala Gly Cys  Leu Ala Ser 
    2870                 2875                 2880             


Leu Gln  Gln Pro Val Gly Ile  Arg Leu Leu Glu Glu  Ala Leu Leu 
    2885                 2890                 2895             


Arg Leu  Leu Pro Ala Glu Leu  Pro Ala Lys Arg Val  Arg Gly Lys 
    2900                 2905                 2910             


Ala Arg  Leu Pro Pro Asp Val  Leu Arg Trp Val Glu  Leu Ala Lys 
    2915                 2920                 2925             


Leu Tyr  Arg Ser Ile Gly Glu  Tyr Asp Val Leu Arg  Gly Ile Phe 
    2930                 2935                 2940             


Thr Ser  Glu Ile Gly Thr Lys  Gln Ile Thr Gln Ser  Ala Leu Leu 
    2945                 2950                 2955             


Ala Glu  Ala Arg Ser Asp Tyr  Ser Glu Ala Ala Lys  Gln Tyr Asp 
    2960                 2965                 2970             


Glu Ala  Leu Asn Lys Gln Asp  Trp Val Asp Gly Glu  Pro Thr Glu 
    2975                 2980                 2985             


Ala Glu  Lys Asp Phe Trp Glu  Leu Ala Ser Leu Asp  Cys Tyr Asn 
    2990                 2995                 3000             


His Leu  Ala Glu Trp Lys Ser  Leu Glu Tyr Cys Ser  Thr Ala Ser 
    3005                 3010                 3015             


Ile Asp  Ser Glu Asn Pro Pro  Asp Leu Asn Lys Ile  Trp Ser Glu 
    3020                 3025                 3030             


Pro Phe  Tyr Gln Glu Thr Tyr  Leu Pro Tyr Met Ile  Arg Ser Lys 
    3035                 3040                 3045             


Leu Lys  Leu Leu Leu Gln Gly  Glu Ala Asp Gln Ser  Leu Leu Thr 
    3050                 3055                 3060             


Phe Ile  Asp Lys Ala Met His  Gly Glu Leu Gln Lys  Ala Ile Leu 
    3065                 3070                 3075             


Glu Leu  His Tyr Ser Gln Glu  Leu Ser Leu Leu Tyr  Leu Leu Gln 
    3080                 3085                 3090             


Asp Asp  Val Asp Arg Ala Lys  Tyr Tyr Ile Gln Asn  Gly Ile Gln 
    3095                 3100                 3105             


Ser Phe  Met Gln Asn Tyr Ser  Ser Ile Asp Val Leu  Leu His Gln 
    3110                 3115                 3120             


Ser Arg  Leu Thr Lys Leu Gln  Ser Val Gln Ala Leu  Thr Glu Ile 
    3125                 3130                 3135             


Gln Glu  Phe Ile Ser Phe Ile  Ser Lys Gln Gly Asn  Leu Ser Ser 
    3140                 3145                 3150             


Gln Val  Pro Leu Lys Arg Leu  Leu Asn Thr Trp Thr  Asn Arg Tyr 
    3155                 3160                 3165             


Pro Asp  Ala Lys Met Asp Pro  Met Asn Ile Trp Asp  Asp Ile Ile 
    3170                 3175                 3180             


Thr Asn  Arg Cys Phe Phe Leu  Ser Lys Ile Glu Glu  Lys Leu Thr 
    3185                 3190                 3195             


Pro Leu  Pro Glu Asp Asn Ser  Met Asn Val Asp Gln  Asp Gly Asp 
    3200                 3205                 3210             


Pro Ser  Asp Arg Met Glu Val  Gln Glu Gln Glu Glu  Asp Ile Ser 
    3215                 3220                 3225             


Ser Leu  Ile Arg Ser Cys Lys  Phe Ser Met Lys Met  Lys Met Ile 
    3230                 3235                 3240             


Asp Ser  Ala Arg Lys Gln Asn  Asn Phe Ser Leu Ala  Met Lys Leu 
    3245                 3250                 3255             


Leu Lys  Glu Leu His Lys Glu  Ser Lys Thr Arg Asp  Asp Trp Leu 
    3260                 3265                 3270             


Val Ser  Trp Val Gln Ser Tyr  Cys Arg Leu Ser His  Cys Arg Ser 
    3275                 3280                 3285             


Arg Ser  Gln Gly Cys Ser Glu  Gln Val Leu Thr Val  Leu Lys Thr 
    3290                 3295                 3300             


Val Ser  Leu Leu Asp Glu Asn  Asn Val Ser Ser Tyr  Leu Ser Lys 
    3305                 3310                 3315             


Asn Ile  Leu Ala Phe Arg Asp  Gln Asn Ile Leu Leu  Gly Thr Thr 
    3320                 3325                 3330             


Tyr Arg  Ile Ile Ala Asn Ala  Leu Ser Ser Glu Pro  Ala Cys Leu 
    3335                 3340                 3345             


Ala Glu  Ile Glu Glu Asp Lys  Ala Arg Arg Ile Leu  Glu Leu Ser 
    3350                 3355                 3360             


Gly Ser  Ser Ser Glu Asp Ser  Glu Lys Val Ile Ala  Gly Leu Tyr 
    3365                 3370                 3375             


Gln Arg  Ala Phe Gln His Leu  Ser Glu Ala Val Gln  Ala Ala Glu 
    3380                 3385                 3390             


Glu Glu  Ala Gln Pro Pro Ser  Trp Ser Cys Gly Pro  Ala Ala Gly 
    3395                 3400                 3405             


Val Ile  Asp Ala Tyr Met Thr  Leu Ala Asp Phe Cys  Asp Gln Gln 
    3410                 3415                 3420             


Leu Arg  Lys Glu Glu Glu Asn  Ala Ser Val Ile Asp  Ser Ala Glu 
    3425                 3430                 3435             


Leu Gln  Ala Tyr Pro Ala Leu  Val Val Glu Lys Met  Leu Lys Ala 
    3440                 3445                 3450             


Leu Lys  Leu Asn Ser Asn Glu  Ala Arg Leu Lys Phe  Pro Arg Leu 
    3455                 3460                 3465             


Leu Gln  Ile Ile Glu Arg Tyr  Pro Glu Glu Thr Leu  Ser Leu Met 
    3470                 3475                 3480             


Thr Lys  Glu Ile Ser Ser Val  Pro Cys Trp Gln Phe  Ile Ser Trp 
    3485                 3490                 3495             


Ile Ser  His Met Val Ala Leu  Leu Asp Lys Asp Gln  Ala Val Ala 
    3500                 3505                 3510             


Val Gln  His Ser Val Glu Glu  Ile Thr Asp Asn Tyr  Pro Gln Ala 
    3515                 3520                 3525             


Ile Val  Tyr Pro Phe Ile Ile  Ser Ser Glu Ser Tyr  Ser Phe Lys 
    3530                 3535                 3540             


Asp Thr  Ser Thr Gly His Lys  Asn Lys Glu Phe Val  Ala Arg Ile 
    3545                 3550                 3555             


Lys Ser  Lys Leu Asp Gln Gly  Gly Val Ile Gln Asp  Phe Ile Asn 
    3560                 3565                 3570             


Ala Leu  Asp Gln Leu Ser Asn  Pro Glu Leu Leu Phe  Lys Asp Trp 
    3575                 3580                 3585             


Ser Asn  Asp Val Arg Ala Glu  Leu Ala Lys Thr Pro  Val Asn Lys 
    3590                 3595                 3600             


Lys Asn  Ile Glu Lys Met Tyr  Glu Arg Met Tyr Ala  Ala Leu Gly 
    3605                 3610                 3615             


Asp Pro  Lys Ala Pro Gly Leu  Gly Ala Phe Arg Arg  Lys Phe Ile 
    3620                 3625                 3630             


Gln Thr  Phe Gly Lys Glu Phe  Asp Lys His Phe Gly  Lys Gly Gly 
    3635                 3640                 3645             


Ser Lys  Leu Leu Arg Met Lys  Leu Ser Asp Phe Asn  Asp Ile Thr 
    3650                 3655                 3660             


Asn Met  Leu Leu Leu Lys Met  Asn Lys Asp Ser Lys  Pro Pro Gly 
    3665                 3670                 3675             


Asn Leu  Lys Glu Cys Ser Pro  Trp Met Ser Asp Phe  Lys Val Glu 
    3680                 3685                 3690             


Phe Leu  Arg Asn Glu Leu Glu  Ile Pro Gly Gln Tyr  Asp Gly Arg 
    3695                 3700                 3705             


Gly Lys  Pro Leu Pro Glu Tyr  His Val Arg Ile Ala  Gly Phe Asp 
    3710                 3715                 3720             


Glu Arg  Val Thr Val Met Ala  Ser Leu Arg Arg Pro  Lys Arg Ile 
    3725                 3730                 3735             


Ile Ile  Arg Gly His Asp Glu  Arg Glu His Pro Phe  Leu Val Lys 
    3740                 3745                 3750             


Gly Gly  Glu Asp Leu Arg Gln  Asp Gln Arg Val Glu  Gln Leu Phe 
    3755                 3760                 3765             


Gln Val  Met Asn Gly Ile Leu  Ala Gln Asp Ser Ala  Cys Ser Gln 
    3770                 3775                 3780             


Arg Ala  Leu Gln Leu Arg Thr  Tyr Ser Val Val Pro  Met Thr Ser 
    3785                 3790                 3795             


Ser Asp  Pro Arg Ala Pro Pro  Cys Glu Tyr Lys Asp  Trp Leu Thr 
    3800                 3805                 3810             


Lys Met  Ser Gly Lys His Asp  Val Gly Ala Tyr Met  Leu Met Tyr 
    3815                 3820                 3825             


Lys Gly  Ala Asn Arg Thr Glu  Thr Val Thr Ser Phe  Arg Lys Arg 
    3830                 3835                 3840             


Glu Ser  Lys Val Pro Ala Asp  Leu Leu Lys Arg Ala  Phe Val Arg 
    3845                 3850                 3855             


Met Ser  Thr Ser Pro Glu Ala  Phe Leu Ala Leu Arg  Ser His Phe 
    3860                 3865                 3870             


Ala Ser  Ser His Ala Leu Ile  Cys Ile Ser His Trp  Ile Leu Gly 
    3875                 3880                 3885             


Ile Gly  Asp Arg His Leu Asn  Asn Phe Met Val Ala  Met Glu Thr 
    3890                 3895                 3900             


Gly Gly  Val Ile Gly Ile Asp  Phe Gly His Ala Phe  Gly Ser Ala 
    3905                 3910                 3915             


Thr Gln  Phe Leu Pro Val Pro  Glu Leu Met Pro Phe  Arg Leu Thr 
    3920                 3925                 3930             


Arg Gln  Phe Ile Asn Leu Met  Leu Pro Met Lys Glu  Thr Gly Leu 
    3935                 3940                 3945             


Met Tyr  Ser Ile Met Val His  Ala Leu Arg Ala Phe  Arg Ser Asp 
    3950                 3955                 3960             


Pro Gly  Leu Leu Thr Asn Thr  Met Asp Val Phe Val  Lys Glu Pro 
    3965                 3970                 3975             


Ser Phe  Asp Trp Lys Asn Phe  Glu Gln Lys Met Leu  Lys Lys Gly 
    3980                 3985                 3990             


Gly Ser  Trp Ile Gln Glu Ile  Asn Val Ala Glu Lys  Asn Trp Tyr 
    3995                 4000                 4005             


Pro Arg  Gln Lys Ile Cys Tyr  Ala Lys Arg Lys Leu  Ala Gly Ala 
    4010                 4015                 4020             


Asn Pro  Ala Val Ile Thr Cys  Asp Glu Leu Leu Leu  Gly His Glu 
    4025                 4030                 4035             


Lys Ala  Pro Ala Phe Arg Asp  Tyr Val Ala Val Ala  Arg Gly Ser 
    4040                 4045                 4050             


Lys Asp  His Asn Ile Arg Ala  Gln Glu Pro Glu Ser  Gly Leu Ser 
    4055                 4060                 4065             


Glu Glu  Thr Gln Val Lys Cys  Leu Met Asp Gln Ala  Thr Asp Pro 
    4070                 4075                 4080             


Asn Ile  Leu Gly Arg Thr Trp  Glu Gly Trp Glu Pro  Trp Met 
    4085                 4090                 4095         


<210>  3583
<211>  359
<212>  PRT
<213>  homo sapiens

<400>  3583

Met Lys Ala Thr Ile Ile Leu Leu Leu Leu Ala Gln Val Ser Trp Ala 
1               5                   10                  15      


Gly Pro Phe Gln Gln Arg Gly Leu Phe Asp Phe Met Leu Glu Asp Glu 
            20                  25                  30          


Ala Ser Gly Ile Gly Pro Glu Val Pro Asp Asp Arg Asp Phe Glu Pro 
        35                  40                  45              


Ser Leu Gly Pro Val Cys Pro Phe Arg Cys Gln Cys His Leu Arg Val 
    50                  55                  60                  


Val Gln Cys Ser Asp Leu Gly Leu Asp Lys Val Pro Lys Asp Leu Pro 
65                  70                  75                  80  


Pro Asp Thr Thr Leu Leu Asp Leu Gln Asn Asn Lys Ile Thr Glu Ile 
                85                  90                  95      


Lys Asp Gly Asp Phe Lys Asn Leu Lys Asn Leu His Ala Leu Ile Leu 
            100                 105                 110         


Val Asn Asn Lys Ile Ser Lys Val Ser Pro Gly Ala Phe Thr Pro Leu 
        115                 120                 125             


Val Lys Leu Glu Arg Leu Tyr Leu Ser Lys Asn Gln Leu Lys Glu Leu 
    130                 135                 140                 


Pro Glu Lys Met Pro Lys Thr Leu Gln Glu Leu Arg Ala His Glu Asn 
145                 150                 155                 160 


Glu Ile Thr Lys Val Arg Lys Val Thr Phe Asn Gly Leu Asn Gln Met 
                165                 170                 175     


Ile Val Ile Glu Leu Gly Thr Asn Pro Leu Lys Ser Ser Gly Ile Glu 
            180                 185                 190         


Asn Gly Ala Phe Gln Gly Met Lys Lys Leu Ser Tyr Ile Arg Ile Ala 
        195                 200                 205             


Asp Thr Asn Ile Thr Ser Ile Pro Gln Gly Leu Pro Pro Ser Leu Thr 
    210                 215                 220                 


Glu Leu His Leu Asp Gly Asn Lys Ile Ser Arg Val Asp Ala Ala Ser 
225                 230                 235                 240 


Leu Lys Gly Leu Asn Asn Leu Ala Lys Leu Gly Leu Ser Phe Asn Ser 
                245                 250                 255     


Ile Ser Ala Val Asp Asn Gly Ser Leu Ala Asn Thr Pro His Leu Arg 
            260                 265                 270         


Glu Leu His Leu Asp Asn Asn Lys Leu Thr Arg Val Pro Gly Gly Leu 
        275                 280                 285             


Ala Glu His Lys Tyr Ile Gln Val Val Tyr Leu His Asn Asn Asn Ile 
    290                 295                 300                 


Ser Val Val Gly Ser Ser Asp Phe Cys Pro Pro Gly His Asn Thr Lys 
305                 310                 315                 320 


Lys Ala Ser Tyr Ser Gly Val Ser Leu Phe Ser Asn Pro Val Gln Tyr 
                325                 330                 335     


Trp Glu Ile Gln Pro Ser Thr Phe Arg Cys Val Tyr Val Arg Ser Ala 
            340                 345                 350         


Ile Gln Leu Gly Asn Tyr Lys 
        355                 


<210>  3584
<211>  135
<212>  PRT
<213>  homo sapiens

<400>  3584

Met Gly Leu Ser Val Arg Glu Leu Asn Arg His Leu Arg Gly Leu Ser 
1               5                   10                  15      


Ala Glu Glu Val Thr Arg Leu Lys Gln Arg Arg Arg Thr Leu Lys Asn 
            20                  25                  30          


Arg Gly Tyr Ala Ala Ser Cys Arg Val Lys Arg Val Cys Gln Lys Glu 
        35                  40                  45              


Glu Leu Gln Lys Gln Lys Ser Glu Leu Glu Arg Glu Val Asp Lys Leu 
    50                  55                  60                  


Ala Arg Glu Asn Ala Ala Met Arg Leu Glu Leu Asp Ala Leu Arg Gly 
65                  70                  75                  80  


Lys Cys Glu Ala Leu Gln Gly Phe Ala Arg Ser Val Ala Ala Ala Arg 
                85                  90                  95      


Gly Pro Ala Thr Leu Val Ala Pro Ala Ser Val Ile Thr Ile Val Lys 
            100                 105                 110         


Ser Thr Pro Gly Ser Gly Ser Gly Pro Ala His Gly Pro Asp Pro Ala 
        115                 120                 125             


His Gly Pro Ala Ser Cys Ser 
    130                 135 


<210>  3585
<211>  367
<212>  PRT
<213>  homo sapiens

<400>  3585

Met Arg Lys Gly Lys Gly Pro Ile Cys Leu Phe Ser Arg Pro Thr Leu 
1               5                   10                  15      


Arg Pro Ser Arg Ser Lys Val Ser Leu Ile Glu Gly Arg Gly Ala Asn 
            20                  25                  30          


Met Ala Ala Arg Trp Arg Phe Trp Cys Val Ser Val Thr Met Val Val 
        35                  40                  45              


Ala Leu Leu Ile Val Cys Asp Val Pro Ser Ala Ser Ala Gln Arg Lys 
    50                  55                  60                  


Lys Glu Met Val Leu Ser Glu Lys Val Ser Gln Leu Met Glu Trp Thr 
65                  70                  75                  80  


Asn Lys Arg Pro Val Ile Arg Met Asn Gly Asp Lys Phe Arg Arg Leu 
                85                  90                  95      


Val Lys Ala Pro Pro Arg Asn Tyr Ser Val Ile Val Met Phe Thr Ala 
            100                 105                 110         


Leu Gln Leu His Arg Gln Cys Val Val Cys Lys Gln Ala Asp Glu Glu 
        115                 120                 125             


Phe Gln Ile Leu Ala Asn Ser Trp Arg Tyr Ser Ser Ala Phe Thr Asn 
    130                 135                 140                 


Arg Ile Phe Phe Ala Met Val Asp Phe Asp Glu Gly Ser Asp Val Phe 
145                 150                 155                 160 


Gln Met Leu Asn Met Asn Ser Ala Pro Thr Phe Ile Asn Phe Pro Ala 
                165                 170                 175     


Lys Gly Lys Pro Lys Arg Gly Asp Thr Tyr Glu Leu Gln Val Arg Gly 
            180                 185                 190         


Phe Ser Ala Glu Gln Ile Ala Arg Trp Ile Ala Asp Arg Thr Asp Val 
        195                 200                 205             


Asn Ile Arg Val Ile Arg Pro Pro Asn Tyr Ala Gly Pro Leu Met Leu 
    210                 215                 220                 


Gly Leu Leu Leu Ala Val Ile Gly Gly Leu Val Tyr Leu Arg Arg Ser 
225                 230                 235                 240 


Asn Met Glu Phe Leu Phe Asn Lys Thr Gly Trp Ala Phe Ala Ala Leu 
                245                 250                 255     


Cys Phe Val Leu Ala Met Thr Ser Gly Gln Met Trp Asn His Ile Arg 
            260                 265                 270         


Gly Pro Pro Tyr Ala His Lys Asn Pro His Thr Gly His Val Asn Tyr 
        275                 280                 285             


Ile His Gly Ser Ser Gln Ala Gln Phe Val Ala Glu Thr His Ile Val 
    290                 295                 300                 


Leu Leu Phe Asn Gly Gly Val Thr Leu Gly Met Val Leu Leu Cys Glu 
305                 310                 315                 320 


Ala Ala Thr Ser Asp Met Asp Ile Gly Lys Arg Lys Ile Met Cys Val 
                325                 330                 335     


Ala Gly Ile Gly Leu Val Val Leu Phe Phe Ser Trp Met Leu Ser Ile 
            340                 345                 350         


Phe Arg Ser Lys Tyr His Gly Tyr Pro Tyr Ser Phe Leu Met Ser 
        355                 360                 365         


<210>  3586
<211>  686
<212>  PRT
<213>  homo sapiens

<400>  3586

Met Leu Leu Arg Gly Val Leu Leu Ala Leu Gln Ala Leu Gln Leu Ala 
1               5                   10                  15      


Gly Ala Leu Asp Leu Pro Ala Gly Ser Cys Ala Phe Glu Glu Ser Thr 
            20                  25                  30          


Cys Gly Phe Asp Ser Val Leu Ala Ser Leu Pro Trp Ile Leu Asn Glu 
        35                  40                  45              


Glu Gly His Tyr Ile Tyr Val Asp Thr Ser Phe Gly Lys Gln Gly Glu 
    50                  55                  60                  


Lys Ala Val Leu Leu Ser Pro Asp Leu Gln Ala Glu Glu Trp Ser Cys 
65                  70                  75                  80  


Leu Arg Leu Val Tyr Gln Ile Thr Thr Ser Ser Glu Ser Leu Ser Asp 
                85                  90                  95      


Pro Ser Gln Leu Asn Leu Tyr Met Arg Phe Glu Asp Glu Ser Phe Asp 
            100                 105                 110         


Arg Leu Leu Trp Ser Ala Lys Glu Pro Ser Asp Ser Trp Leu Ile Ala 
        115                 120                 125             


Ser Leu Asp Leu Gln Asn Ser Ser Lys Lys Phe Lys Ile Leu Ile Glu 
    130                 135                 140                 


Gly Val Leu Gly Gln Gly Asn Thr Ala Ser Ile Ala Leu Phe Glu Ile 
145                 150                 155                 160 


Lys Met Thr Thr Gly Tyr Cys Ile Glu Cys Asp Phe Glu Glu Asn His 
                165                 170                 175     


Leu Cys Gly Phe Val Asn Arg Trp Asn Pro Asn Val Asn Trp Phe Val 
            180                 185                 190         


Gly Gly Gly Ser Ile Arg Asn Val His Ser Ile Leu Pro Gln Asp His 
        195                 200                 205             


Thr Phe Lys Ser Glu Leu Gly His Tyr Met Tyr Val Asp Ser Val Tyr 
    210                 215                 220                 


Val Lys His Phe Gln Glu Val Ala Gln Leu Ile Ser Pro Leu Thr Thr 
225                 230                 235                 240 


Ala Pro Met Ala Gly Cys Leu Ser Phe Tyr Tyr Gln Ile Gln Gln Gly 
                245                 250                 255     


Asn Asp Asn Val Phe Ser Leu Tyr Thr Arg Asp Val Ala Gly Leu Tyr 
            260                 265                 270         


Glu Glu Ile Trp Lys Ala Asp Arg Pro Gly Asn Ala Ala Trp Asn Leu 
        275                 280                 285             


Ala Glu Val Glu Phe Ser Ala Pro Tyr Pro Met Glu Val Ile Phe Glu 
    290                 295                 300                 


Val Ala Phe Asn Gly Pro Lys Gly Gly Tyr Val Ala Leu Asp Asp Ile 
305                 310                 315                 320 


Ser Phe Ser Pro Val His Cys Gln Asn Gln Thr Glu Leu Leu Phe Ser 
                325                 330                 335     


Ala Val Glu Ala Ser Cys Asn Phe Glu Gln Asp Leu Cys Asn Phe Tyr 
            340                 345                 350         


Gln Asp Lys Glu Gly Pro Gly Trp Thr Arg Val Lys Val Lys Pro Asn 
        355                 360                 365             


Met Tyr Arg Ala Gly Asp His Thr Thr Gly Leu Gly Tyr Tyr Leu Leu 
    370                 375                 380                 


Ala Asn Thr Lys Phe Thr Ser Gln Pro Gly Tyr Ile Gly Arg Leu Tyr 
385                 390                 395                 400 


Gly Pro Ser Leu Pro Gly Asn Leu Gln Tyr Cys Leu Arg Phe His Tyr 
                405                 410                 415     


Ala Ile Tyr Gly Phe Leu Lys Met Ser Asp Thr Leu Ala Val Tyr Ile 
            420                 425                 430         


Phe Glu Glu Asn His Val Val Gln Glu Lys Ile Trp Ser Val Leu Glu 
        435                 440                 445             


Ser Pro Arg Gly Val Trp Met Gln Ala Glu Ile Thr Phe Lys Lys Pro 
    450                 455                 460                 


Met Pro Thr Lys Val Val Phe Met Ser Leu Cys Lys Ser Phe Trp Asp 
465                 470                 475                 480 


Cys Gly Leu Val Ala Leu Asp Asp Ile Thr Ile Gln Leu Gly Ser Cys 
                485                 490                 495     


Ser Ser Ser Glu Lys Leu Pro Pro Pro Pro Gly Glu Cys Thr Phe Glu 
            500                 505                 510         


Gln Asp Glu Cys Thr Phe Thr Gln Glu Lys Arg Asn Arg Ser Ser Trp 
        515                 520                 525             


His Arg Arg Arg Gly Glu Thr Pro Thr Ser Tyr Thr Gly Pro Lys Gly 
    530                 535                 540                 


Asp His Thr Thr Gly Val Gly Tyr Tyr Met Tyr Ile Glu Ala Ser His 
545                 550                 555                 560 


Met Val Tyr Gly Gln Lys Ala Arg Leu Leu Ser Arg Pro Leu Arg Gly 
                565                 570                 575     


Val Ser Gly Lys His Cys Leu Thr Phe Phe Tyr His Met Tyr Gly Gly 
            580                 585                 590         


Gly Thr Gly Leu Leu Ser Val Tyr Leu Lys Lys Glu Glu Asp Ser Glu 
        595                 600                 605             


Glu Ser Leu Leu Trp Arg Arg Arg Gly Glu Gln Ser Ile Ser Trp Leu 
    610                 615                 620                 


Arg Ala Leu Ile Glu Tyr Ser Cys Glu Arg Gln His Gln Ile Ile Phe 
625                 630                 635                 640 


Glu Ala Ile Arg Gly Val Ser Ile Arg Ser Asp Ile Ala Ile Asp Asp 
                645                 650                 655     


Val Lys Phe Gln Ala Gly Pro Cys Gly Glu Met Glu Asp Thr Thr Gln 
            660                 665                 670         


Gln Ser Ser Gly Tyr Ser Glu Asp Leu Asn Glu Ile Glu Tyr 
        675                 680                 685     


<210>  3587
<211>  1156
<212>  PRT
<213>  homo sapiens

<400>  3587

Met Gly Asp Thr Ala Pro Pro Gln Ala Pro Ala Gly Gly Leu Gly Gly 
1               5                   10                  15      


Ala Ser Gly Ala Gly Leu Leu Gly Gly Gly Ser Val Thr Pro Arg Val 
            20                  25                  30          


His Ser Ala Ile Val Glu Arg Leu Arg Ala Arg Ile Ala Val Cys Arg 
        35                  40                  45              


Gln His His Leu Ser Cys Glu Gly Arg Tyr Glu Arg Gly Arg Ala Glu 
    50                  55                  60                  


Ser Ser Asp Arg Glu Arg Glu Ser Thr Leu Gln Leu Leu Ser Leu Val 
65                  70                  75                  80  


Gln His Gly Gln Gly Ala Arg Lys Ala Gly Lys His Thr Lys Ala Thr 
                85                  90                  95      


Ala Thr Ala Ala Thr Thr Thr Ala Pro Pro Pro Pro Pro Ala Ala Pro 
            100                 105                 110         


Pro Ala Ala Ser Gln Ala Ala Ala Thr Ala Ala Pro Pro Pro Pro Pro 
        115                 120                 125             


Asp Tyr His His His His Gln Gln His Leu Leu Asn Ser Ser Asn Asn 
    130                 135                 140                 


Gly Gly Ser Gly Gly Ile Asn Gly Glu Gln Gln Pro Pro Ala Ser Thr 
145                 150                 155                 160 


Pro Gly Asp Gln Arg Asn Ser Ala Leu Ile Ala Leu Gln Gly Ser Leu 
                165                 170                 175     


Lys Arg Lys Gln Val Val Asn Leu Ser Pro Ala Asn Ser Lys Arg Pro 
            180                 185                 190         


Asn Gly Phe Val Asp Asn Ser Phe Leu Asp Ile Lys Arg Ile Arg Val 
        195                 200                 205             


Gly Glu Asn Leu Ser Ala Gly Gln Gly Gly Leu Gln Ile Asn Asn Gly 
    210                 215                 220                 


Gln Ser Gln Ile Met Ser Gly Thr Leu Pro Met Ser Gln Ala Pro Leu 
225                 230                 235                 240 


Arg Lys Thr Asn Thr Leu Pro Ser His Thr His Ser Pro Gly Asn Gly 
                245                 250                 255     


Leu Phe Asn Met Gly Leu Lys Glu Val Lys Lys Glu Pro Gly Glu Thr 
            260                 265                 270         


Leu Ser Cys Ser Lys His Met Asp Gly Gln Met Thr Gln Glu Asn Ile 
        275                 280                 285             


Phe Pro Asn Arg Tyr Gly Asp Asp Pro Gly Glu Gln Leu Met Asp Pro 
    290                 295                 300                 


Glu Leu Gln Glu Leu Phe Asn Glu Leu Thr Asn Ile Ser Val Pro Pro 
305                 310                 315                 320 


Met Ser Asp Leu Glu Leu Glu Asn Met Ile Asn Ala Thr Ile Lys Gln 
                325                 330                 335     


Asp Asp Pro Phe Asn Ile Asp Leu Gly Gln Gln Ser Gln Arg Ser Thr 
            340                 345                 350         


Pro Arg Pro Ser Leu Pro Met Glu Lys Ile Val Ile Lys Ser Glu Tyr 
        355                 360                 365             


Ser Pro Gly Leu Thr Gln Gly Pro Ser Gly Ser Pro Gln Leu Arg Pro 
    370                 375                 380                 


Pro Ser Ala Gly Pro Ala Phe Ser Met Ala Asn Ser Ala Leu Ser Thr 
385                 390                 395                 400 


Ser Ser Pro Ile Pro Ser Val Pro Gln Ser Gln Ala Gln Pro Gln Thr 
                405                 410                 415     


Gly Ser Gly Ala Ser Arg Ala Leu Pro Ser Trp Gln Glu Val Ser His 
            420                 425                 430         


Ala Gln Gln Leu Lys Gln Ile Ala Ala Asn Arg Gln Gln His Ala Arg 
        435                 440                 445             


Met Gln Gln His Gln Gln Gln His Gln Pro Thr Asn Trp Ser Ala Leu 
    450                 455                 460                 


Pro Ser Ser Ala Gly Pro Ser Pro Gly Pro Phe Gly Gln Glu Lys Ile 
465                 470                 475                 480 


Pro Ser Pro Ser Phe Gly Gln Gln Thr Phe Ser Pro Gln Ser Ser Pro 
                485                 490                 495     


Met Pro Gly Val Ala Gly Gly Ser Gly Gln Ser Lys Val Met Ala Asn 
            500                 505                 510         


Tyr Met Tyr Lys Ala Gly Pro Ser Ala Gln Gly Gly His Leu Asp Val 
        515                 520                 525             


Leu Met Gln Gln Lys Pro Gln Asp Leu Ser Arg Ser Phe Ile Asn Asn 
    530                 535                 540                 


Pro His Pro Ala Met Glu Pro Arg Gln Gly Asn Thr Lys Pro Leu Phe 
545                 550                 555                 560 


His Phe Asn Ser Asp Gln Ala Asn Gln Gln Met Pro Ser Val Leu Pro 
                565                 570                 575     


Ser Gln Asn Lys Pro Ser Leu Leu His Tyr Thr Gln Gln Gln Gln Gln 
            580                 585                 590         


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln 
        595                 600                 605             


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Ser Ser Ile 
    610                 615                 620                 


Ser Ala Gln Gln Gln Gln Gln Gln Gln Ser Ser Ile Ser Ala Gln Gln 
625                 630                 635                 640 


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln 
                645                 650                 655     


Gln Gln Gln Gln Gln Gln Gln Gln Gln Pro Ser Ser Gln Pro Ala Gln 
            660                 665                 670         


Ser Leu Pro Ser Gln Pro Leu Leu Arg Ser Pro Leu Pro Leu Gln Gln 
        675                 680                 685             


Lys Leu Leu Leu Gln Gln Met Gln Asn Gln Pro Ile Ala Gly Met Gly 
    690                 695                 700                 


Tyr Gln Val Ser Gln Gln Gln Arg Gln Asp Gln His Ser Val Val Gly 
705                 710                 715                 720 


Gln Asn Thr Gly Pro Ser Pro Ser Pro Asn Pro Cys Ser Asn Pro Asn 
                725                 730                 735     


Thr Gly Ser Gly Tyr Met Asn Ser Gln Gln Ser Leu Leu Asn Gln Gln 
            740                 745                 750         


Leu Met Gly Lys Lys Gln Thr Leu Gln Arg Gln Ile Met Glu Gln Lys 
        755                 760                 765             


Gln Gln Leu Leu Leu Gln Gln Gln Met Leu Ala Asp Ala Glu Lys Ile 
    770                 775                 780                 


Ala Pro Gln Asp Gln Ile Asn Arg His Leu Ser Arg Pro Pro Pro Asp 
785                 790                 795                 800 


Tyr Lys Asp Gln Arg Arg Asn Val Gly Asn Met Gln Pro Thr Ala Gln 
                805                 810                 815     


Tyr Ser Gly Gly Ser Ser Thr Ile Ser Leu Asn Ser Asn Gln Ala Leu 
            820                 825                 830         


Ala Asn Pro Val Ser Thr His Thr Ile Leu Thr Pro Asn Ser Ser Leu 
        835                 840                 845             


Leu Ser Thr Ser His Gly Thr Arg Met Pro Ser Leu Ser Thr Ala Val 
    850                 855                 860                 


Gln Asn Met Gly Met Tyr Gly Asn Leu Pro Cys Asn Gln Pro Asn Thr 
865                 870                 875                 880 


Tyr Ser Val Thr Ser Gly Met Asn Gln Leu Thr Gln Gln Arg Asn Pro 
                885                 890                 895     


Lys Gln Leu Leu Ala Asn Gln Asn Asn Pro Met Met Pro Arg Pro Pro 
            900                 905                 910         


Thr Leu Gly Pro Ser Asn Asn Asn Asn Val Ala Thr Phe Gly Ala Gly 
        915                 920                 925             


Ser Val Gly Asn Ser Gln Gln Leu Arg Pro Asn Leu Thr His Ser Met 
    930                 935                 940                 


Ala Ser Met Pro Pro Gln Arg Thr Ser Asn Val Met Ile Thr Ser Asn 
945                 950                 955                 960 


Thr Thr Ala Pro Asn Trp Ala Ser Gln Glu Gly Thr Ser Lys Gln Gln 
                965                 970                 975     


Glu Ala Leu Thr Ser Ala Gly Val Arg Phe Pro Thr Gly Thr Pro Ala 
            980                 985                 990         


Ala Tyr Thr Pro Asn Gln Ser Leu  Gln Gln Ala Val Gly  Ser Gln Gln 
        995                 1000                 1005             


Phe Ser  Gln Arg Ala Val Ala  Pro Pro Asn Gln Leu  Thr Pro Ala 
    1010                 1015                 1020             


Val Gln  Met Arg Pro Met Asn  Gln Met Ser Gln Thr  Leu Asn Gly 
    1025                 1030                 1035             


Gln Thr  Met Gly Pro Leu Arg  Gly Leu Asn Leu Arg  Pro Asn Gln 
    1040                 1045                 1050             


Leu Ser  Thr Gln Ile Leu Pro  Asn Leu Asn Gln Ser  Gly Thr Gly 
    1055                 1060                 1065             


Leu Asn  Gln Ser Arg Thr Gly  Ile Asn Gln Pro Pro  Ser Leu Thr 
    1070                 1075                 1080             


Pro Ser  Asn Phe Pro Ser Pro  Asn Gln Ser Ser Arg  Ala Phe Gln 
    1085                 1090                 1095             


Gly Thr  Asp His Ser Ser Asp  Leu Ala Phe Asp Phe  Leu Ser Gln 
    1100                 1105                 1110             


Gln Asn  Asp Asn Met Gly Pro  Ala Leu Asn Ser Asp  Ala Asp Phe 
    1115                 1120                 1125             


Ile Asp  Ser Leu Leu Lys Thr  Glu Pro Gly Asn Asp  Asp Trp Met 
    1130                 1135                 1140             


Lys Asp  Ile Asn Leu Asp Glu  Ile Leu Gly Asn Asn  Ser 
    1145                 1150                 1155     


<210>  3588
<211>  1152
<212>  PRT
<213>  homo sapiens

<400>  3588

Met Ala Asp Leu Ser Leu Ala Asp Ala Leu Thr Glu Pro Ser Pro Asp 
1               5                   10                  15      


Ile Glu Gly Glu Ile Lys Arg Asp Phe Ile Ala Thr Leu Glu Ala Glu 
            20                  25                  30          


Ala Phe Asp Asp Val Val Gly Glu Thr Val Gly Lys Thr Asp Tyr Ile 
        35                  40                  45              


Pro Leu Leu Asp Val Asp Glu Lys Thr Gly Asn Ser Glu Ser Lys Lys 
    50                  55                  60                  


Lys Pro Cys Ser Glu Thr Ser Gln Ile Glu Asp Thr Pro Ser Ser Lys 
65                  70                  75                  80  


Pro Thr Leu Leu Ala Asn Gly Gly His Gly Val Glu Gly Ser Asp Thr 
                85                  90                  95      


Thr Gly Ser Pro Thr Glu Phe Leu Glu Glu Lys Met Ala Tyr Gln Glu 
            100                 105                 110         


Tyr Pro Asn Ser Gln Asn Trp Pro Glu Asp Thr Asn Phe Cys Phe Gln 
        115                 120                 125             


Pro Glu Gln Val Val Asp Pro Ile Gln Thr Asp Pro Phe Lys Met Tyr 
    130                 135                 140                 


His Asp Asp Asp Leu Ala Asp Leu Val Phe Pro Ser Ser Ala Thr Ala 
145                 150                 155                 160 


Asp Thr Ser Ile Phe Ala Gly Gln Asn Asp Pro Leu Lys Asp Ser Tyr 
                165                 170                 175     


Gly Met Ser Pro Cys Asn Thr Ala Val Val Pro Gln Gly Trp Ser Val 
            180                 185                 190         


Glu Ala Leu Asn Ser Pro His Ser Glu Ser Phe Val Ser Pro Glu Ala 
        195                 200                 205             


Val Ala Glu Pro Pro Gln Pro Thr Ala Val Pro Leu Glu Leu Ala Lys 
    210                 215                 220                 


Glu Ile Glu Met Ala Ser Glu Glu Arg Pro Pro Ala Gln Ala Leu Glu 
225                 230                 235                 240 


Ile Met Met Gly Leu Lys Thr Thr Asp Met Ala Pro Ser Lys Glu Thr 
                245                 250                 255     


Glu Met Ala Leu Ala Lys Asp Met Ala Leu Ala Thr Lys Thr Glu Val 
            260                 265                 270         


Ala Leu Ala Lys Asp Met Glu Ser Pro Thr Lys Leu Asp Val Thr Leu 
        275                 280                 285             


Ala Lys Asp Met Gln Pro Ser Met Glu Ser Asp Met Ala Leu Val Lys 
    290                 295                 300                 


Asp Met Glu Leu Pro Thr Glu Lys Glu Val Ala Leu Val Lys Asp Val 
305                 310                 315                 320 


Arg Trp Pro Thr Glu Thr Asp Val Ser Ser Ala Lys Asn Val Val Leu 
                325                 330                 335     


Pro Thr Glu Thr Glu Val Ala Pro Ala Lys Asp Val Thr Leu Leu Lys 
            340                 345                 350         


Glu Thr Glu Arg Ala Ser Pro Ile Lys Met Asp Leu Ala Pro Ser Lys 
        355                 360                 365             


Asp Met Gly Pro Pro Lys Glu Asn Lys Lys Glu Thr Glu Arg Ala Ser 
    370                 375                 380                 


Pro Ile Lys Met Asp Leu Ala Pro Ser Lys Asp Met Gly Pro Pro Lys 
385                 390                 395                 400 


Glu Asn Lys Ile Val Pro Ala Lys Asp Leu Val Leu Leu Ser Glu Ile 
                405                 410                 415     


Glu Val Ala Gln Ala Asn Asp Ile Ile Ser Ser Thr Glu Ile Ser Ser 
            420                 425                 430         


Ala Glu Lys Val Ala Leu Ser Ser Glu Thr Glu Val Ala Leu Ala Arg 
        435                 440                 445             


Asp Met Thr Leu Pro Pro Glu Thr Asn Val Ile Leu Thr Lys Asp Lys 
    450                 455                 460                 


Ala Leu Pro Leu Glu Ala Glu Val Ala Pro Val Lys Asp Met Ala Gln 
465                 470                 475                 480 


Leu Pro Glu Thr Glu Ile Ala Pro Ala Lys Asp Val Ala Pro Ser Thr 
                485                 490                 495     


Val Lys Glu Val Gly Leu Leu Lys Asp Met Ser Pro Leu Ser Glu Thr 
            500                 505                 510         


Glu Met Ala Leu Gly Lys Asp Val Thr Pro Pro Pro Glu Thr Glu Val 
        515                 520                 525             


Val Leu Ile Lys Asn Val Cys Leu Pro Pro Glu Met Glu Val Ala Leu 
    530                 535                 540                 


Thr Glu Asp Gln Val Pro Ala Leu Lys Thr Glu Ala Pro Leu Ala Lys 
545                 550                 555                 560 


Asp Gly Val Leu Thr Leu Ala Asn Asn Val Thr Pro Ala Lys Asp Val 
                565                 570                 575     


Pro Pro Leu Ser Glu Thr Glu Ala Thr Pro Val Pro Ile Lys Asp Met 
            580                 585                 590         


Glu Ile Ala Gln Thr Gln Lys Gly Ile Ser Glu Asp Ser His Leu Glu 
        595                 600                 605             


Ser Leu Gln Asp Val Gly Gln Ser Ala Ala Pro Thr Phe Met Ile Ser 
    610                 615                 620                 


Pro Glu Thr Val Thr Gly Thr Gly Lys Lys Cys Ser Leu Pro Ala Glu 
625                 630                 635                 640 


Glu Asp Ser Val Leu Glu Lys Leu Gly Glu Arg Lys Pro Cys Asn Ser 
                645                 650                 655     


Gln Pro Ser Glu Leu Ser Ser Glu Thr Ser Gly Ile Ala Arg Pro Glu 
            660                 665                 670         


Glu Gly Arg Pro Val Val Ser Gly Thr Gly Asn Asp Ile Thr Thr Pro 
        675                 680                 685             


Pro Asn Lys Glu Leu Pro Pro Ser Pro Glu Lys Lys Thr Lys Pro Leu 
    690                 695                 700                 


Ala Thr Thr Gln Pro Ala Lys Thr Ser Thr Ser Lys Ala Lys Thr Gln 
705                 710                 715                 720 


Pro Thr Ser Leu Pro Lys Gln Pro Ala Pro Thr Thr Ile Gly Gly Leu 
                725                 730                 735     


Asn Lys Lys Pro Met Ser Leu Ala Ser Gly Leu Val Pro Ala Ala Pro 
            740                 745                 750         


Pro Lys Arg Pro Ala Val Ala Ser Ala Arg Pro Ser Ile Leu Pro Ser 
        755                 760                 765             


Lys Asp Val Lys Pro Lys Pro Ile Ala Asp Ala Lys Ala Pro Glu Lys 
    770                 775                 780                 


Arg Ala Ser Pro Ser Lys Pro Ala Ser Ala Pro Ala Ser Arg Ser Gly 
785                 790                 795                 800 


Ser Lys Ser Thr Gln Thr Val Ala Lys Thr Thr Thr Ala Ala Ala Val 
                805                 810                 815     


Ala Ser Thr Gly Pro Ser Ser Arg Ser Pro Ser Thr Leu Leu Pro Lys 
            820                 825                 830         


Lys Pro Thr Ala Ile Lys Thr Glu Gly Lys Pro Ala Glu Val Lys Lys 
        835                 840                 845             


Met Thr Ala Lys Ser Val Pro Ala Asp Leu Ser Arg Pro Lys Ser Thr 
    850                 855                 860                 


Ser Thr Ser Ser Met Lys Lys Thr Thr Thr Leu Ser Gly Thr Ala Pro 
865                 870                 875                 880 


Ala Ala Gly Val Val Pro Ser Arg Val Lys Ala Thr Pro Met Pro Ser 
                885                 890                 895     


Arg Pro Ser Thr Thr Pro Phe Ile Asp Lys Lys Pro Thr Ser Ala Lys 
            900                 905                 910         


Pro Ser Ser Thr Thr Pro Arg Leu Ser Arg Leu Ala Thr Asn Thr Ser 
        915                 920                 925             


Ala Pro Asp Leu Lys Asn Val Arg Ser Lys Val Gly Ser Thr Glu Asn 
    930                 935                 940                 


Ile Lys His Gln Pro Gly Gly Gly Arg Ala Lys Val Glu Lys Lys Thr 
945                 950                 955                 960 


Glu Ala Ala Ala Thr Thr Arg Lys Pro Glu Ser Asn Ala Val Thr Lys 
                965                 970                 975     


Thr Ala Gly Pro Ile Ala Ser Ala Gln Lys Gln Pro Ala Gly Lys Val 
            980                 985                 990         


Gln Ile Val Ser Lys Lys Val Ser  Tyr Ser His Ile Gln  Ser Lys Cys 
        995                 1000                 1005             


Gly Ser  Lys Asp Asn Ile Lys  His Val Pro Gly Gly  Gly Asn Val 
    1010                 1015                 1020             


Gln Ile  Gln Asn Lys Lys Val  Asp Ile Ser Lys Val  Ser Ser Lys 
    1025                 1030                 1035             


Cys Gly  Ser Lys Ala Asn Ile  Lys His Lys Pro Gly  Gly Gly Asp 
    1040                 1045                 1050             


Val Lys  Ile Glu Ser Gln Lys  Leu Asn Phe Lys Glu  Lys Ala Gln 
    1055                 1060                 1065             


Ala Lys  Val Gly Ser Leu Asp  Asn Val Gly His Leu  Pro Ala Gly 
    1070                 1075                 1080             


Gly Ala  Val Lys Thr Glu Gly  Gly Gly Ser Glu Ala  Pro Leu Cys 
    1085                 1090                 1095             


Pro Gly  Pro Pro Ala Gly Glu  Glu Pro Ala Ile Ser  Glu Ala Ala 
    1100                 1105                 1110             


Pro Glu  Ala Gly Ala Pro Thr  Ser Ala Ser Gly Leu  Asn Gly His 
    1115                 1120                 1125             


Pro Thr  Leu Ser Gly Gly Gly  Asp Gln Arg Glu Ala  Gln Thr Leu 
    1130                 1135                 1140             


Asp Ser  Gln Ile Gln Glu Thr  Ser Ile 
    1145                 1150         


<210>  3589
<211>  99
<212>  PRT
<213>  homo sapiens

<400>  3589

Met Ala Asp Leu Ser Leu Ala Asp Ala Leu Thr Glu Pro Ser Pro Asp 
1               5                   10                  15      


Ile Glu Gly Glu Ile Lys Arg Asp Phe Ile Ala Thr Leu Glu Ala Glu 
            20                  25                  30          


Ala Phe Asp Asp Val Val Gly Glu Thr Val Gly Lys Thr Asp Tyr Ile 
        35                  40                  45              


Pro Leu Leu Asp Val Asp Glu Lys Thr Gly Asn Ser Glu Ser Lys Lys 
    50                  55                  60                  


Lys Pro Cys Ser Glu Thr Ser Gln Ile Glu Asp Thr Pro Ser Ser Lys 
65                  70                  75                  80  


Pro Thr Leu Leu Ala Asn Gly Gly His Gly Val Glu Gly Ser Asp Thr 
                85                  90                  95      


Thr Glu Ala 
            


<210>  3590
<211>  1135
<212>  PRT
<213>  homo sapiens

<400>  3590

Met Ala Asp Leu Ser Leu Ala Asp Ala Leu Thr Glu Pro Ser Pro Asp 
1               5                   10                  15      


Ile Glu Gly Glu Ile Lys Arg Asp Phe Ile Ala Thr Leu Glu Ala Glu 
            20                  25                  30          


Ala Phe Asp Asp Val Val Gly Glu Thr Val Gly Lys Thr Asp Tyr Ile 
        35                  40                  45              


Pro Leu Leu Asp Val Asp Glu Lys Thr Gly Asn Ser Glu Ser Lys Lys 
    50                  55                  60                  


Lys Pro Cys Ser Glu Thr Ser Gln Ile Glu Asp Thr Pro Ser Ser Lys 
65                  70                  75                  80  


Pro Thr Leu Leu Ala Asn Gly Gly His Gly Val Glu Gly Ser Asp Thr 
                85                  90                  95      


Thr Gly Ser Pro Thr Glu Phe Leu Glu Glu Lys Met Ala Tyr Gln Glu 
            100                 105                 110         


Tyr Pro Asn Ser Gln Asn Trp Pro Glu Asp Thr Asn Phe Cys Phe Gln 
        115                 120                 125             


Pro Glu Gln Val Val Asp Pro Ile Gln Thr Asp Pro Phe Lys Met Tyr 
    130                 135                 140                 


His Asp Asp Asp Leu Ala Asp Leu Val Phe Pro Ser Ser Ala Thr Ala 
145                 150                 155                 160 


Asp Thr Ser Ile Phe Ala Gly Gln Asn Asp Pro Leu Lys Asp Ser Tyr 
                165                 170                 175     


Gly Met Ser Pro Cys Asn Thr Ala Val Val Pro Gln Gly Trp Ser Val 
            180                 185                 190         


Glu Ala Leu Asn Ser Pro His Ser Glu Ser Phe Val Ser Pro Glu Ala 
        195                 200                 205             


Val Ala Glu Pro Pro Gln Pro Thr Ala Val Pro Leu Glu Leu Ala Lys 
    210                 215                 220                 


Glu Ile Glu Met Ala Ser Glu Glu Arg Pro Pro Ala Gln Ala Leu Glu 
225                 230                 235                 240 


Ile Met Met Gly Leu Lys Thr Thr Asp Met Ala Pro Ser Lys Glu Thr 
                245                 250                 255     


Glu Met Ala Leu Ala Lys Asp Met Ala Leu Ala Thr Lys Thr Glu Val 
            260                 265                 270         


Ala Leu Ala Lys Asp Met Glu Ser Pro Thr Lys Leu Asp Val Thr Leu 
        275                 280                 285             


Ala Lys Asp Met Gln Pro Ser Met Glu Ser Asp Met Ala Leu Val Lys 
    290                 295                 300                 


Asp Met Glu Leu Pro Thr Glu Lys Glu Val Ala Leu Val Lys Asp Val 
305                 310                 315                 320 


Arg Trp Pro Thr Glu Thr Asp Val Ser Ser Ala Lys Asn Val Val Leu 
                325                 330                 335     


Pro Thr Glu Thr Glu Val Ala Pro Ala Lys Asp Val Thr Leu Leu Lys 
            340                 345                 350         


Glu Thr Glu Arg Ala Ser Pro Ile Lys Met Asp Leu Ala Pro Ser Lys 
        355                 360                 365             


Asp Met Gly Pro Pro Lys Glu Asn Lys Lys Glu Thr Glu Arg Ala Ser 
    370                 375                 380                 


Pro Ile Lys Met Asp Leu Ala Pro Ser Lys Asp Met Gly Pro Pro Lys 
385                 390                 395                 400 


Glu Asn Lys Ile Val Pro Ala Lys Asp Leu Val Leu Leu Ser Glu Ile 
                405                 410                 415     


Glu Val Ala Gln Ala Asn Asp Ile Ile Ser Ser Thr Glu Ile Ser Ser 
            420                 425                 430         


Ala Glu Lys Val Ala Leu Ser Ser Glu Thr Glu Val Ala Leu Ala Arg 
        435                 440                 445             


Asp Met Thr Leu Pro Pro Glu Thr Asn Val Ile Leu Thr Lys Asp Lys 
    450                 455                 460                 


Ala Leu Pro Leu Glu Ala Glu Val Ala Pro Val Lys Asp Met Ala Gln 
465                 470                 475                 480 


Leu Pro Glu Thr Glu Ile Ala Pro Ala Lys Asp Val Ala Pro Ser Thr 
                485                 490                 495     


Val Lys Glu Val Gly Leu Leu Lys Asp Met Ser Pro Leu Ser Glu Thr 
            500                 505                 510         


Glu Met Ala Leu Gly Lys Asp Val Thr Pro Pro Pro Glu Thr Glu Val 
        515                 520                 525             


Val Leu Ile Lys Asn Val Cys Leu Pro Pro Glu Met Glu Val Ala Leu 
    530                 535                 540                 


Thr Glu Asp Gln Val Pro Ala Leu Lys Thr Glu Ala Pro Leu Ala Lys 
545                 550                 555                 560 


Asp Gly Val Leu Thr Leu Ala Asn Asn Val Thr Pro Ala Lys Asp Val 
                565                 570                 575     


Pro Pro Leu Ser Glu Thr Glu Ala Thr Pro Val Pro Ile Lys Asp Met 
            580                 585                 590         


Glu Ile Ala Gln Thr Gln Lys Gly Ile Ser Glu Asp Ser His Leu Glu 
        595                 600                 605             


Ser Leu Gln Asp Val Gly Gln Ser Ala Ala Pro Thr Phe Met Ile Ser 
    610                 615                 620                 


Pro Glu Thr Val Thr Gly Thr Gly Lys Lys Cys Ser Leu Pro Ala Glu 
625                 630                 635                 640 


Glu Asp Ser Val Leu Glu Lys Leu Gly Glu Arg Lys Pro Cys Asn Ser 
                645                 650                 655     


Gln Pro Ser Glu Leu Ser Ser Glu Thr Ser Gly Ile Ala Arg Pro Glu 
            660                 665                 670         


Glu Gly Arg Pro Val Val Ser Gly Thr Gly Asn Asp Ile Thr Thr Pro 
        675                 680                 685             


Pro Asn Lys Glu Leu Pro Pro Ser Pro Glu Lys Lys Thr Lys Pro Leu 
    690                 695                 700                 


Ala Thr Thr Gln Pro Ala Lys Thr Ser Thr Ser Lys Ala Lys Thr Gln 
705                 710                 715                 720 


Pro Thr Ser Leu Pro Lys Gln Pro Ala Pro Thr Thr Ile Gly Gly Leu 
                725                 730                 735     


Asn Lys Lys Pro Met Ser Leu Ala Ser Gly Leu Val Pro Ala Ala Pro 
            740                 745                 750         


Pro Lys Arg Pro Ala Val Ala Ser Ala Arg Pro Ser Ile Leu Pro Ser 
        755                 760                 765             


Lys Asp Val Lys Pro Lys Pro Ile Ala Asp Ala Lys Ala Pro Glu Lys 
    770                 775                 780                 


Arg Ala Ser Pro Ser Lys Pro Ala Ser Ala Pro Ala Ser Arg Ser Gly 
785                 790                 795                 800 


Ser Lys Ser Thr Gln Thr Val Ala Lys Thr Thr Thr Ala Ala Ala Val 
                805                 810                 815     


Ala Ser Thr Gly Pro Ser Ser Arg Ser Pro Ser Thr Leu Leu Pro Lys 
            820                 825                 830         


Lys Pro Thr Ala Ile Lys Thr Glu Gly Lys Pro Ala Glu Val Lys Lys 
        835                 840                 845             


Met Thr Ala Lys Ser Val Pro Ala Asp Leu Ser Arg Pro Lys Ser Thr 
    850                 855                 860                 


Ser Thr Ser Ser Met Lys Lys Thr Thr Thr Leu Ser Gly Thr Ala Pro 
865                 870                 875                 880 


Ala Ala Gly Val Val Pro Ser Arg Val Lys Ala Thr Pro Met Pro Ser 
                885                 890                 895     


Arg Pro Ser Thr Thr Pro Phe Ile Asp Lys Lys Pro Thr Ser Ala Lys 
            900                 905                 910         


Pro Ser Ser Thr Thr Pro Arg Leu Ser Arg Leu Ala Thr Asn Thr Ser 
        915                 920                 925             


Ala Pro Asp Leu Lys Asn Val Arg Ser Lys Val Gly Ser Thr Glu Asn 
    930                 935                 940                 


Ile Lys His Gln Pro Gly Gly Gly Arg Ala Lys Val Glu Lys Lys Thr 
945                 950                 955                 960 


Glu Ala Ala Ala Thr Thr Arg Lys Pro Glu Ser Asn Ala Val Thr Lys 
                965                 970                 975     


Thr Ala Gly Pro Ile Ala Ser Ala Gln Lys Gln Pro Ala Gly Lys Val 
            980                 985                 990         


Gln Ile Val Ser Lys Lys Val Ser  Tyr Ser His Ile Gln  Ser Lys Cys 
        995                 1000                 1005             


Gly Ser  Lys Asp Asn Ile Lys  His Val Pro Gly Gly  Gly Asn Val 
    1010                 1015                 1020             


Gln Ile  Gln Asn Lys Lys Val  Asp Ile Ser Lys Val  Ser Ser Lys 
    1025                 1030                 1035             


Cys Gly  Ser Lys Ala Asn Ile  Lys His Lys Pro Gly  Gly Gly Asp 
    1040                 1045                 1050             


Val Lys  Ile Glu Ser Gln Lys  Leu Asn Phe Lys Glu  Lys Ala Gln 
    1055                 1060                 1065             


Ala Lys  Val Gly Ser Leu Asp  Asn Val Gly His Leu  Pro Ala Gly 
    1070                 1075                 1080             


Gly Ala  Val Lys Ile Glu Thr  Tyr Arg Leu Thr Phe  Arg Ala Asn 
    1085                 1090                 1095             


Ala Arg  Ala Arg Thr Asp His  Gly Ala Asp Ile Val  Ser Arg Pro 
    1100                 1105                 1110             


Pro His  Phe Pro Gly Gly Pro  Asn Ser Gly Ser Arg  Val Leu Gly 
    1115                 1120                 1125             


Pro Leu  Ser Arg Ala Val His  
    1130                 1135 


<210>  3591
<211>  316
<212>  PRT
<213>  homo sapiens

<400>  3591

Met Leu Arg Arg Arg Gly Ser Pro Gly Met Gly Val His Val Gly Ala 
1               5                   10                  15      


Ala Leu Gly Ala Leu Trp Phe Cys Leu Thr Gly Ala Leu Glu Val Gln 
            20                  25                  30          


Val Pro Glu Asp Pro Val Val Ala Leu Val Gly Thr Asp Ala Thr Leu 
        35                  40                  45              


Cys Cys Ser Phe Ser Pro Glu Pro Gly Phe Ser Leu Ala Gln Leu Asn 
    50                  55                  60                  


Leu Ile Trp Gln Leu Thr Asp Thr Lys Gln Leu Val His Ser Phe Ala 
65                  70                  75                  80  


Glu Gly Gln Asp Gln Gly Ser Ala Tyr Ala Asn Arg Thr Ala Leu Phe 
                85                  90                  95      


Pro Asp Leu Leu Ala Gln Gly Asn Ala Ser Leu Arg Leu Gln Arg Val 
            100                 105                 110         


Arg Val Ala Asp Glu Gly Ser Phe Thr Cys Phe Val Ser Ile Arg Asp 
        115                 120                 125             


Phe Gly Ser Ala Ala Val Ser Leu Gln Val Ala Ala Pro Tyr Ser Lys 
    130                 135                 140                 


Pro Ser Met Thr Leu Glu Pro Asn Lys Asp Leu Arg Pro Gly Asp Thr 
145                 150                 155                 160 


Val Thr Ile Thr Cys Ser Ser Tyr Arg Gly Tyr Pro Glu Ala Glu Val 
                165                 170                 175     


Phe Trp Gln Asp Gly Gln Gly Val Pro Leu Thr Gly Asn Val Thr Thr 
            180                 185                 190         


Ser Gln Met Ala Asn Glu Gln Gly Leu Phe Asp Val His Ser Val Leu 
        195                 200                 205             


Arg Val Val Leu Gly Ala Asn Gly Thr Tyr Ser Cys Leu Val Arg Asn 
    210                 215                 220                 


Pro Val Leu Gln Gln Asp Ala His Gly Ser Val Thr Ile Thr Gly Gln 
225                 230                 235                 240 


Pro Met Thr Phe Pro Pro Glu Ala Leu Trp Val Thr Val Gly Leu Ser 
                245                 250                 255     


Val Cys Leu Ile Ala Leu Leu Val Ala Leu Ala Phe Val Cys Trp Arg 
            260                 265                 270         


Lys Ile Lys Gln Ser Cys Glu Glu Glu Asn Ala Gly Ala Glu Asp Gln 
        275                 280                 285             


Asp Gly Glu Gly Glu Gly Ser Lys Thr Ala Leu Gln Pro Leu Lys His 
    290                 295                 300                 


Ser Asp Ser Lys Glu Asp Asp Gly Gln Glu Ile Ala 
305                 310                 315     


<210>  3592
<211>  437
<212>  PRT
<213>  homo sapiens

<400>  3592

Met Gly Arg Lys Lys Ile Gln Ile Thr Arg Ile Met Asp Glu Arg Asn 
1               5                   10                  15      


Arg Gln Thr Leu Arg Lys Lys Gly Leu Asn Gly Cys Glu Ser Pro Asp 
            20                  25                  30          


Ala Asp Asp Tyr Phe Glu His Ser Pro Leu Ser Glu Asp Arg Phe Ser 
        35                  40                  45              


Lys Leu Asn Glu Asp Ser Asp Phe Ile Phe Lys Arg Gly Pro Pro Gly 
    50                  55                  60                  


Leu Pro Pro Gln Asn Phe Ser Met Ser Val Thr Val Pro Val Thr Ser 
65                  70                  75                  80  


Pro Asn Ala Leu Ser Tyr Thr Asn Pro Gly Ser Ser Leu Val Ser Pro 
                85                  90                  95      


Ser Leu Ala Ala Ser Ser Thr Leu Thr Asp Ser Ser Met Leu Ser Pro 
            100                 105                 110         


Pro Gln Thr Thr Leu His Arg Asn Val Ser Pro Gly Ala Pro Gln Arg 
        115                 120                 125             


Pro Pro Ser Thr Gly Asn Ala Gly Gly Met Leu Ser Thr Thr Asp Leu 
    130                 135                 140                 


Thr Val Pro Asn Gly Ala Gly Ser Ser Pro Val Gly Asn Gly Phe Val 
145                 150                 155                 160 


Asn Ser Arg Ala Ser Pro Asn Leu Ile Gly Ala Thr Gly Ala Asn Ser 
                165                 170                 175     


Leu Gly Lys Val Met Pro Thr Lys Ser Pro Pro Pro Pro Gly Gly Gly 
            180                 185                 190         


Asn Leu Gly Met Asn Ser Arg Lys Pro Asp Leu Arg Val Val Ile Pro 
        195                 200                 205             


Pro Ser Ser Lys Gly Met Met Pro Pro Leu Ser Glu Glu Glu Glu Leu 
    210                 215                 220                 


Glu Leu Asn Thr Gln Arg Ile Ser Ser Ser Gln Ala Thr Gln Pro Leu 
225                 230                 235                 240 


Ala Thr Pro Val Val Ser Val Thr Thr Pro Ser Leu Pro Pro Gln Gly 
                245                 250                 255     


Leu Val Tyr Ser Ala Met Pro Thr Ala Tyr Asn Thr Asp Tyr Ser Leu 
            260                 265                 270         


Thr Ser Ala Asp Leu Ser Ala Leu Gln Gly Phe Asn Ser Pro Gly Met 
        275                 280                 285             


Leu Ser Leu Gly Gln Val Ser Ala Trp Gln Gln His His Leu Gly Gln 
    290                 295                 300                 


Ala Ala Leu Ser Ser Leu Val Ala Gly Gly Gln Leu Ser Gln Gly Ser 
305                 310                 315                 320 


Asn Leu Ser Ile Asn Thr Asn Gln Asn Ile Ser Ile Lys Ser Glu Pro 
                325                 330                 335     


Ile Ser Pro Pro Arg Asp Arg Met Thr Pro Ser Gly Phe Gln Gln Gln 
            340                 345                 350         


Gln Gln Gln Gln Gln Gln Gln Gln Pro Pro Pro Pro Pro Gln Pro Gln 
        355                 360                 365             


Pro Gln Pro Pro Gln Pro Gln Pro Arg Gln Glu Met Gly Arg Ser Pro 
    370                 375                 380                 


Val Asp Ser Leu Ser Ser Ser Ser Ser Ser Tyr Asp Gly Ser Asp Arg 
385                 390                 395                 400 


Glu Asp Pro Arg Gly Asp Phe His Ser Pro Ile Val Leu Gly Arg Pro 
                405                 410                 415     


Pro Asn Thr Glu Asp Arg Glu Ser Pro Ser Val Lys Arg Met Arg Met 
            420                 425                 430         


Asp Ala Trp Val Thr 
        435         


<210>  3593
<211>  344
<212>  PRT
<213>  homo sapiens

<400>  3593

Met Val Arg Ala Arg His Gln Pro Gly Gly Leu Cys Leu Leu Leu Leu 
1               5                   10                  15      


Leu Leu Cys Gln Phe Met Glu Asp Arg Ser Ala Gln Ala Gly Asn Cys 
            20                  25                  30          


Trp Leu Arg Gln Ala Lys Asn Gly Arg Cys Gln Val Leu Tyr Lys Thr 
        35                  40                  45              


Glu Leu Ser Lys Glu Glu Cys Cys Ser Thr Gly Arg Leu Ser Thr Ser 
    50                  55                  60                  


Trp Thr Glu Glu Asp Val Asn Asp Asn Thr Leu Phe Lys Trp Met Ile 
65                  70                  75                  80  


Phe Asn Gly Gly Ala Pro Asn Cys Ile Pro Cys Lys Glu Thr Cys Glu 
                85                  90                  95      


Asn Val Asp Cys Gly Pro Gly Lys Lys Cys Arg Met Asn Lys Lys Asn 
            100                 105                 110         


Lys Pro Arg Cys Val Cys Ala Pro Asp Cys Ser Asn Ile Thr Trp Lys 
        115                 120                 125             


Gly Pro Val Cys Gly Leu Asp Gly Lys Thr Tyr Arg Asn Glu Cys Ala 
    130                 135                 140                 


Leu Leu Lys Ala Arg Cys Lys Glu Gln Pro Glu Leu Glu Val Gln Tyr 
145                 150                 155                 160 


Gln Gly Arg Cys Lys Lys Thr Cys Arg Asp Val Phe Cys Pro Gly Ser 
                165                 170                 175     


Ser Thr Cys Val Val Asp Gln Thr Asn Asn Ala Tyr Cys Val Thr Cys 
            180                 185                 190         


Asn Arg Ile Cys Pro Glu Pro Ala Ser Ser Glu Gln Tyr Leu Cys Gly 
        195                 200                 205             


Asn Asp Gly Val Thr Tyr Ser Ser Ala Cys His Leu Arg Lys Ala Thr 
    210                 215                 220                 


Cys Leu Leu Gly Arg Ser Ile Gly Leu Ala Tyr Glu Gly Lys Cys Ile 
225                 230                 235                 240 


Lys Ala Lys Ser Cys Glu Asp Ile Gln Cys Thr Gly Gly Lys Lys Cys 
                245                 250                 255     


Leu Trp Asp Phe Lys Val Gly Arg Gly Arg Cys Ser Leu Cys Asp Glu 
            260                 265                 270         


Leu Cys Pro Asp Ser Lys Ser Asp Glu Pro Val Cys Ala Ser Asp Asn 
        275                 280                 285             


Ala Thr Tyr Ala Ser Glu Cys Ala Met Lys Glu Ala Ala Cys Ser Ser 
    290                 295                 300                 


Gly Val Leu Leu Glu Val Lys His Ser Gly Ser Cys Asn Ser Ile Ser 
305                 310                 315                 320 


Glu Asp Thr Glu Glu Glu Glu Glu Asp Glu Asp Gln Asp Tyr Ser Phe 
                325                 330                 335     


Pro Ile Ser Ser Ile Leu Glu Trp 
            340                 


<210>  3594
<211>  502
<212>  PRT
<213>  homo sapiens

<400>  3594

Met Ala Trp Ala Leu Lys Leu Pro Leu Ala Asp Glu Val Ile Glu Ser 
1               5                   10                  15      


Gly Leu Val Gln Asp Phe Asp Ala Ser Leu Ser Gly Ile Gly Gln Glu 
            20                  25                  30          


Leu Gly Ala Gly Ala Tyr Ser Met Ser Asp Val Leu Ala Leu Pro Ile 
        35                  40                  45              


Phe Lys Gln Glu Glu Ser Ser Leu Pro Pro Asp Asn Glu Asn Lys Ile 
    50                  55                  60                  


Leu Pro Phe Gln Tyr Val Leu Cys Ala Ala Thr Ser Pro Ala Val Lys 
65                  70                  75                  80  


Leu His Asp Glu Thr Leu Thr Tyr Leu Asn Gln Gly Gln Ser Tyr Glu 
                85                  90                  95      


Ile Arg Met Leu Asp Asn Arg Lys Leu Gly Glu Leu Pro Glu Ile Asn 
            100                 105                 110         


Gly Lys Leu Val Lys Ser Ile Phe Arg Val Val Phe His Asp Arg Arg 
        115                 120                 125             


Leu Gln Tyr Thr Glu His Gln Gln Leu Glu Gly Trp Arg Trp Asn Arg 
    130                 135                 140                 


Pro Gly Asp Arg Ile Leu Asp Ile Asp Ile Pro Met Ser Val Gly Ile 
145                 150                 155                 160 


Ile Asp Pro Arg Ala Asn Pro Thr Gln Leu Asn Thr Val Glu Phe Leu 
                165                 170                 175     


Trp Asp Pro Ala Lys Arg Thr Ser Val Phe Ile Gln Val His Cys Ile 
            180                 185                 190         


Ser Thr Glu Phe Thr Met Arg Lys His Gly Gly Glu Lys Gly Val Pro 
        195                 200                 205             


Phe Arg Val Gln Ile Asp Thr Phe Lys Glu Asn Glu Asn Gly Glu Tyr 
    210                 215                 220                 


Thr Glu His Leu His Ser Ala Ser Cys Gln Ile Lys Val Phe Lys Pro 
225                 230                 235                 240 


Lys Gly Ala Asp Arg Lys Gln Lys Thr Asp Arg Glu Lys Met Glu Lys 
                245                 250                 255     


Arg Thr Pro His Glu Lys Glu Lys Tyr Gln Pro Ser Tyr Glu Thr Thr 
            260                 265                 270         


Ile Leu Thr Glu Cys Ser Pro Trp Pro Glu Ile Thr Tyr Val Asn Asn 
        275                 280                 285             


Ser Pro Ser Pro Gly Phe Asn Ser Ser His Ser Ser Phe Ser Leu Gly 
    290                 295                 300                 


Glu Gly Asn Gly Ser Pro Asn His Gln Pro Glu Pro Pro Pro Pro Val 
305                 310                 315                 320 


Thr Asp Asn Leu Leu Pro Thr Thr Thr Pro Gln Glu Ala Gln Gln Trp 
                325                 330                 335     


Leu His Arg Asn Arg Phe Ser Thr Phe Thr Arg Leu Phe Thr Asn Phe 
            340                 345                 350         


Ser Gly Ala Asp Leu Leu Lys Leu Thr Arg Asp Asp Val Ile Gln Ile 
        355                 360                 365             


Cys Gly Pro Ala Asp Gly Ile Arg Leu Phe Asn Ala Leu Lys Gly Arg 
    370                 375                 380                 


Met Val Arg Pro Arg Leu Thr Ile Tyr Val Cys Gln Glu Ser Leu Gln 
385                 390                 395                 400 


Leu Arg Glu Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Lys His Glu 
                405                 410                 415     


Asp Gly Asp Ser Asn Gly Thr Phe Phe Val Tyr His Ala Ile Tyr Leu 
            420                 425                 430         


Glu Glu Leu Thr Ala Val Glu Leu Thr Glu Lys Ile Ala Gln Leu Phe 
        435                 440                 445             


Ser Ile Ser Pro Cys Gln Ile Ser Gln Ile Tyr Lys Gln Gly Pro Thr 
    450                 455                 460                 


Gly Ile His Val Leu Ile Ser Asp Glu Met Ile Gln Asn Phe Gln Glu 
465                 470                 475                 480 


Glu Ala Cys Phe Ile Leu Asp Thr Met Lys Ala Glu Thr Asn Asp Ser 
                485                 490                 495     


Tyr His Ile Ile Leu Lys 
            500         


<210>  3595
<211>  304
<212>  PRT
<213>  homo sapiens

<400>  3595

Met Ile Tyr Thr Met Lys Lys Val His Ala Leu Trp Ala Ser Val Cys 
1               5                   10                  15      


Leu Leu Leu Asn Leu Ala Pro Ala Pro Leu Asn Ala Asp Ser Glu Glu 
            20                  25                  30          


Asp Glu Glu His Thr Ile Ile Thr Asp Thr Glu Leu Pro Pro Leu Lys 
        35                  40                  45              


Leu Met His Ser Phe Cys Ala Phe Lys Ala Asp Asp Gly Pro Cys Lys 
    50                  55                  60                  


Ala Ile Met Lys Arg Phe Phe Phe Asn Ile Phe Thr Arg Gln Cys Glu 
65                  70                  75                  80  


Glu Phe Ile Tyr Gly Gly Cys Glu Gly Asn Gln Asn Arg Phe Glu Ser 
                85                  90                  95      


Leu Glu Glu Cys Lys Lys Met Cys Thr Arg Asp Asn Ala Asn Arg Ile 
            100                 105                 110         


Ile Lys Thr Thr Leu Gln Gln Glu Lys Pro Asp Phe Cys Phe Leu Glu 
        115                 120                 125             


Glu Asp Pro Gly Ile Cys Arg Gly Tyr Ile Thr Arg Tyr Phe Tyr Asn 
    130                 135                 140                 


Asn Gln Thr Lys Gln Cys Glu Arg Phe Lys Tyr Gly Gly Cys Leu Gly 
145                 150                 155                 160 


Asn Met Asn Asn Phe Glu Thr Leu Glu Glu Cys Lys Asn Ile Cys Glu 
                165                 170                 175     


Asp Gly Pro Asn Gly Phe Gln Val Asp Asn Tyr Gly Thr Gln Leu Asn 
            180                 185                 190         


Ala Val Asn Asn Ser Leu Thr Pro Gln Ser Thr Lys Val Pro Ser Leu 
        195                 200                 205             


Phe Glu Phe His Gly Pro Ser Trp Cys Leu Thr Pro Ala Asp Arg Gly 
    210                 215                 220                 


Leu Cys Arg Ala Asn Glu Asn Arg Phe Tyr Tyr Asn Ser Val Ile Gly 
225                 230                 235                 240 


Lys Cys Arg Pro Phe Lys Tyr Ser Gly Cys Gly Gly Asn Glu Asn Asn 
                245                 250                 255     


Phe Thr Ser Lys Gln Glu Cys Leu Arg Ala Cys Lys Lys Gly Phe Ile 
            260                 265                 270         


Gln Arg Ile Ser Lys Gly Gly Leu Ile Lys Thr Lys Arg Lys Arg Lys 
        275                 280                 285             


Lys Gln Arg Val Lys Ile Ala Tyr Glu Glu Ile Phe Val Lys Asn Met 
    290                 295                 300                 


<210>  3596
<211>  251
<212>  PRT
<213>  homo sapiens

<400>  3596

Met Ile Tyr Thr Met Lys Lys Val His Ala Leu Trp Ala Ser Val Cys 
1               5                   10                  15      


Leu Leu Leu Asn Leu Ala Pro Ala Pro Leu Asn Ala Asp Ser Glu Glu 
            20                  25                  30          


Asp Glu Glu His Thr Ile Ile Thr Asp Thr Glu Leu Pro Pro Leu Lys 
        35                  40                  45              


Leu Met His Ser Phe Cys Ala Phe Lys Ala Asp Asp Gly Pro Cys Lys 
    50                  55                  60                  


Ala Ile Met Lys Arg Phe Phe Phe Asn Ile Phe Thr Arg Gln Cys Glu 
65                  70                  75                  80  


Glu Phe Ile Tyr Gly Gly Cys Glu Gly Asn Gln Asn Arg Phe Glu Ser 
                85                  90                  95      


Leu Glu Glu Cys Lys Lys Met Cys Thr Arg Asp Asn Ala Asn Arg Ile 
            100                 105                 110         


Ile Lys Thr Thr Leu Gln Gln Glu Lys Pro Asp Phe Cys Phe Leu Glu 
        115                 120                 125             


Glu Asp Pro Gly Ile Cys Arg Gly Tyr Ile Thr Arg Tyr Phe Tyr Asn 
    130                 135                 140                 


Asn Gln Thr Lys Gln Cys Glu Arg Phe Lys Tyr Gly Gly Cys Leu Gly 
145                 150                 155                 160 


Asn Met Asn Asn Phe Glu Thr Leu Glu Glu Cys Lys Asn Ile Cys Glu 
                165                 170                 175     


Asp Gly Pro Asn Gly Phe Gln Val Asp Asn Tyr Gly Thr Gln Leu Asn 
            180                 185                 190         


Ala Val Asn Asn Ser Leu Thr Pro Gln Ser Thr Lys Val Pro Ser Leu 
        195                 200                 205             


Phe Val Thr Lys Glu Gly Thr Asn Asp Gly Trp Lys Asn Ala Ala His 
    210                 215                 220                 


Ile Tyr Gln Val Phe Leu Asn Ala Phe Cys Ile His Ala Ser Met Phe 
225                 230                 235                 240 


Phe Leu Gly Leu Asp Ser Ile Ser Cys Leu Cys 
                245                 250     


<210>  3597
<211>  272
<212>  PRT
<213>  homo sapiens

<400>  3597

Met Lys Gly Lys Lys Gly Ile Val Ala Ala Ser Gly Ser Glu Thr Glu 
1               5                   10                  15      


Asp Glu Asp Ser Met Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala Gly 
            20                  25                  30          


Ser Gly Lys Arg Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val Gln 
        35                  40                  45              


Ile Leu Arg Asp Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro Ser 
    50                  55                  60                  


Glu Gln Glu Lys Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr Leu 
65                  70                  75                  80  


Gln Val Cys Asn Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro Asp 
                85                  90                  95      


Met Leu Arg Lys Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile Ser Arg 
            100                 105                 110         


Arg Gly Ala Lys Ile Ser Glu Thr Ser Ser Val Glu Ser Val Met Gly 
        115                 120                 125             


Ile Lys Asn Phe Met Pro Ala Leu Glu Glu Thr Pro Phe His Ser Cys 
    130                 135                 140                 


Thr Ala Gly Pro Asn Pro Thr Leu Gly Arg Pro Leu Ser Pro Lys Pro 
145                 150                 155                 160 


Ser Ser Pro Gly Ser Val Leu Ala Arg Pro Ser Val Ile Cys His Thr 
                165                 170                 175     


Thr Val Thr Ala Leu Lys Asp Val Pro Phe Ser Leu Cys Gln Ser Val 
            180                 185                 190         


Gly Val Gly Gln Asn Thr Asp Ile Gln Gln Ile Ala Ala Lys Asn Phe 
        195                 200                 205             


Thr Asp Thr Ser Leu Met Tyr Pro Glu Asp Thr Cys Lys Ser Gly Pro 
    210                 215                 220                 


Ser Thr Asn Thr Gln Ser Gly Leu Phe Asn Thr Pro Pro Pro Thr Pro 
225                 230                 235                 240 


Pro Asp Leu Asn Gln Asp Phe Ser Gly Phe Gln Leu Leu Val Asp Val 
                245                 250                 255     


Ala Leu Lys Arg Ala Ala Glu Met Glu Leu Gln Ala Lys Leu Thr Ala 
            260                 265                 270         


<210>  3598
<211>  401
<212>  PRT
<213>  homo sapiens

<400>  3598

Met Val Leu Ala Gln Ser Arg Val Ser Ala Gly Val Gly Ser Pro His 
1               5                   10                  15      


Cys Ser Gly Ser Gly Gly Gly Gly Ser Asp Ser Phe Pro Trp Pro Ala 
            20                  25                  30          


Ser His Pro Gly Asn Pro Gln Cys Ser Phe Ser Thr Ala Phe Leu Ala 
        35                  40                  45              


Ser Pro Arg Leu Ser Arg Gly Thr Leu Ala Tyr Leu Pro Pro Ala Pro 
    50                  55                  60                  


Trp Ser Ser Leu Ala Thr Pro Ser Ala Leu Leu Gly Ser Ser Cys Ala 
65                  70                  75                  80  


Pro Pro Pro Pro Pro Ala Arg Cys Pro Gln Pro Arg Ala Leu Ser Pro 
                85                  90                  95      


Glu Leu Gly Thr Lys Ala Gly Pro Arg Arg Pro His Arg Trp Glu Leu 
            100                 105                 110         


Pro Arg Ser Pro Ser Gln Gly Ala Gln Gly Pro Ala Pro Arg Arg Arg 
        115                 120                 125             


Leu Leu Glu Thr Met Lys Gly Ile Val Ala Ala Ser Gly Ser Glu Thr 
    130                 135                 140                 


Glu Asp Glu Asp Ser Met Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala 
145                 150                 155                 160 


Gly Ser Gly Lys Arg Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val 
                165                 170                 175     


Gln Ile Leu Arg Asp Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro 
            180                 185                 190         


Ser Glu Gln Glu Lys Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr 
        195                 200                 205             


Leu Gln Val Cys Asn Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro 
    210                 215                 220                 


Asp Met Leu Arg Lys Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile Ser 
225                 230                 235                 240 


Arg Arg Gly Ala Lys Ile Ser Glu Thr Ser Ser Val Glu Ser Val Met 
                245                 250                 255     


Gly Ile Lys Asn Phe Met Pro Ala Leu Glu Glu Thr Pro Phe His Ser 
            260                 265                 270         


Cys Thr Ala Gly Pro Asn Pro Thr Leu Gly Arg Pro Leu Ser Pro Lys 
        275                 280                 285             


Pro Ser Ser Pro Gly Ser Val Leu Ala Arg Pro Ser Val Ile Cys His 
    290                 295                 300                 


Thr Thr Val Thr Ala Leu Lys Asp Val Pro Phe Ser Leu Cys Gln Ser 
305                 310                 315                 320 


Val Gly Val Gly Gln Asn Thr Asp Ile Gln Gln Ile Ala Ala Lys Asn 
                325                 330                 335     


Phe Thr Asp Thr Ser Leu Met Tyr Pro Glu Asp Thr Cys Lys Ser Gly 
            340                 345                 350         


Pro Ser Thr Asn Thr Gln Ser Gly Leu Phe Asn Thr Pro Pro Pro Thr 
        355                 360                 365             


Pro Pro Asp Leu Asn Gln Asp Phe Ser Gly Phe Gln Leu Leu Val Asp 
    370                 375                 380                 


Val Ala Leu Lys Arg Ala Ala Glu Met Glu Leu Gln Ala Lys Leu Thr 
385                 390                 395                 400 


Ala 
    


<210>  3599
<211>  286
<212>  PRT
<213>  homo sapiens

<400>  3599

Met Thr Cys Ser Gly Lys Ser Cys Ala Leu Ala Arg Ser Ser Leu Thr 
1               5                   10                  15      


Ser Ser Gln Gly Ile Val Ala Ala Ser Gly Ser Glu Thr Glu Asp Glu 
            20                  25                  30          


Asp Ser Met Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala Gly Ser Gly 
        35                  40                  45              


Lys Arg Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val Gln Ile Leu 
    50                  55                  60                  


Arg Asp Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro Ser Glu Gln 
65                  70                  75                  80  


Glu Lys Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr Leu Gln Val 
                85                  90                  95      


Cys Asn Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro Asp Met Leu 
            100                 105                 110         


Arg Lys Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile Ser Arg Arg Gly 
        115                 120                 125             


Ala Lys Ile Ser Glu Thr Ser Ser Val Glu Ser Val Met Gly Ile Lys 
    130                 135                 140                 


Asn Phe Met Pro Ala Leu Glu Glu Thr Pro Phe His Ser Cys Thr Ala 
145                 150                 155                 160 


Gly Pro Asn Pro Thr Leu Gly Arg Pro Leu Ser Pro Lys Pro Ser Ser 
                165                 170                 175     


Pro Gly Ser Val Leu Ala Arg Pro Ser Val Ile Cys His Thr Thr Val 
            180                 185                 190         


Thr Ala Leu Lys Asp Val Pro Phe Ser Leu Cys Gln Ser Val Gly Val 
        195                 200                 205             


Gly Gln Asn Thr Asp Ile Gln Gln Ile Ala Ala Lys Asn Phe Thr Asp 
    210                 215                 220                 


Thr Ser Leu Met Tyr Pro Glu Asp Thr Cys Lys Ser Gly Pro Ser Thr 
225                 230                 235                 240 


Asn Thr Gln Ser Gly Leu Phe Asn Thr Pro Pro Pro Thr Pro Pro Asp 
                245                 250                 255     


Leu Asn Gln Asp Phe Ser Gly Phe Gln Leu Leu Val Asp Val Ala Leu 
            260                 265                 270         


Lys Arg Ala Ala Glu Met Glu Leu Gln Ala Lys Leu Thr Ala 
        275                 280                 285     


<210>  3600
<211>  272
<212>  PRT
<213>  homo sapiens

<400>  3600

Met Lys Gly Lys Lys Gly Ile Val Ala Ala Ser Gly Ser Glu Thr Glu 
1               5                   10                  15      


Asp Glu Asp Ser Met Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala Gly 
            20                  25                  30          


Ser Gly Lys Arg Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val Gln 
        35                  40                  45              


Ile Leu Arg Asp Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro Ser 
    50                  55                  60                  


Glu Gln Glu Lys Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr Leu 
65                  70                  75                  80  


Gln Val Cys Asn Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro Asp 
                85                  90                  95      


Met Leu Arg Lys Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile Ser Arg 
            100                 105                 110         


Arg Gly Ala Lys Ile Ser Glu Thr Ser Ser Val Glu Ser Val Met Gly 
        115                 120                 125             


Ile Lys Asn Phe Met Pro Ala Leu Glu Glu Thr Pro Phe His Ser Cys 
    130                 135                 140                 


Thr Ala Gly Pro Asn Pro Thr Leu Gly Arg Pro Leu Ser Pro Lys Pro 
145                 150                 155                 160 


Ser Ser Pro Gly Ser Val Leu Ala Arg Pro Ser Val Ile Cys His Thr 
                165                 170                 175     


Thr Val Thr Ala Leu Lys Asp Val Pro Phe Ser Leu Cys Gln Ser Val 
            180                 185                 190         


Gly Val Gly Gln Asn Thr Asp Ile Gln Gln Ile Ala Ala Lys Asn Phe 
        195                 200                 205             


Thr Asp Thr Ser Leu Met Tyr Pro Glu Asp Thr Cys Lys Ser Gly Pro 
    210                 215                 220                 


Ser Thr Asn Thr Gln Ser Gly Leu Phe Asn Thr Pro Pro Pro Thr Pro 
225                 230                 235                 240 


Pro Asp Leu Asn Gln Asp Phe Ser Gly Phe Gln Leu Leu Val Asp Val 
                245                 250                 255     


Ala Leu Lys Arg Ala Ala Glu Met Glu Leu Gln Ala Lys Leu Thr Ala 
            260                 265                 270         


<210>  3601
<211>  252
<212>  PRT
<213>  homo sapiens

<400>  3601

Met Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala Gly Ser Gly Lys Arg 
1               5                   10                  15      


Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val Gln Ile Leu Arg Asp 
            20                  25                  30          


Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro Ser Glu Gln Glu Lys 
        35                  40                  45              


Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr Leu Gln Val Cys Asn 
    50                  55                  60                  


Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro Asp Met Leu Arg Lys 
65                  70                  75                  80  


Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile Ser Arg Arg Gly Ala Lys 
                85                  90                  95      


Ile Ser Glu Thr Ser Ser Val Glu Ser Val Met Gly Ile Lys Asn Phe 
            100                 105                 110         


Met Pro Ala Leu Glu Glu Thr Pro Phe His Ser Cys Thr Ala Gly Pro 
        115                 120                 125             


Asn Pro Thr Leu Gly Arg Pro Leu Ser Pro Lys Pro Ser Ser Pro Gly 
    130                 135                 140                 


Ser Val Leu Ala Arg Pro Ser Val Ile Cys His Thr Thr Val Thr Ala 
145                 150                 155                 160 


Leu Lys Asp Val Pro Phe Ser Leu Cys Gln Ser Val Gly Val Gly Gln 
                165                 170                 175     


Asn Thr Asp Ile Gln Gln Ile Ala Ala Lys Asn Phe Thr Asp Thr Ser 
            180                 185                 190         


Leu Met Tyr Pro Glu Asp Thr Cys Lys Ser Gly Pro Ser Thr Asn Thr 
        195                 200                 205             


Gln Ser Gly Leu Phe Asn Thr Pro Pro Pro Thr Pro Pro Asp Leu Asn 
    210                 215                 220                 


Gln Asp Phe Ser Gly Phe Gln Leu Leu Val Asp Val Ala Leu Lys Arg 
225                 230                 235                 240 


Ala Ala Glu Met Glu Leu Gln Ala Lys Leu Thr Ala 
                245                 250         


<210>  3602
<211>  1066
<212>  PRT
<213>  homo sapiens

<400>  3602

Met Gly Phe Glu Leu Asp Arg Phe Asp Gly Asp Val Asp Pro Asp Leu 
1               5                   10                  15      


Lys Cys Ala Leu Cys His Lys Val Leu Glu Asp Pro Leu Thr Thr Pro 
            20                  25                  30          


Cys Gly His Val Phe Cys Ala Gly Cys Val Leu Pro Trp Val Val Gln 
        35                  40                  45              


Glu Gly Ser Cys Pro Ala Arg Cys Arg Gly Arg Leu Ser Ala Lys Glu 
    50                  55                  60                  


Leu Asn His Val Leu Pro Leu Lys Arg Leu Ile Leu Lys Leu Asp Ile 
65                  70                  75                  80  


Lys Cys Ala Tyr Ala Thr Arg Gly Cys Gly Arg Val Val Lys Leu Gln 
                85                  90                  95      


Gln Leu Pro Glu His Leu Glu Arg Cys Asp Phe Ala Pro Ala Arg Cys 
            100                 105                 110         


Arg His Ala Gly Cys Gly Gln Val Leu Leu Arg Arg Asp Val Glu Ala 
        115                 120                 125             


His Met Arg Asp Ala Cys Asp Ala Arg Pro Val Gly Arg Cys Gln Glu 
    130                 135                 140                 


Gly Cys Gly Leu Pro Leu Thr His Gly Glu Gln Arg Ala Gly Gly His 
145                 150                 155                 160 


Cys Cys Ala Arg Ala Leu Arg Ala His Asn Gly Ala Leu Gln Ala Arg 
                165                 170                 175     


Leu Gly Ala Leu His Lys Ala Leu Lys Lys Glu Ala Leu Arg Ala Gly 
            180                 185                 190         


Lys Arg Glu Lys Ser Leu Val Ala Gln Leu Ala Ala Ala Gln Leu Glu 
        195                 200                 205             


Leu Gln Met Thr Ala Leu Arg Tyr Gln Lys Lys Phe Thr Glu Tyr Ser 
    210                 215                 220                 


Ala Arg Leu Asp Ser Leu Ser Arg Cys Val Ala Ala Pro Pro Gly Gly 
225                 230                 235                 240 


Lys Gly Glu Glu Thr Lys Ser Leu Thr Leu Val Leu His Arg Asp Ser 
                245                 250                 255     


Gly Ser Leu Gly Phe Asn Ile Ile Gly Gly Arg Pro Ser Val Asp Asn 
            260                 265                 270         


His Asp Gly Ser Ser Ser Glu Gly Ile Phe Val Ser Lys Ile Val Asp 
        275                 280                 285             


Ser Gly Pro Ala Ala Lys Glu Gly Gly Leu Gln Ile His Asp Arg Ile 
    290                 295                 300                 


Ile Glu Val Asn Gly Arg Asp Leu Ser Arg Ala Thr His Asp Gln Ala 
305                 310                 315                 320 


Val Glu Ala Phe Lys Thr Ala Lys Glu Pro Ile Val Val Gln Val Leu 
                325                 330                 335     


Arg Arg Thr Pro Arg Thr Lys Met Phe Thr Pro Pro Ser Glu Ser Gln 
            340                 345                 350         


Leu Val Asp Thr Gly Thr Gln Thr Asp Ile Thr Phe Glu His Ile Met 
        355                 360                 365             


Ala Leu Thr Lys Met Ser Ser Pro Ser Pro Pro Val Leu Asp Pro Tyr 
    370                 375                 380                 


Leu Leu Pro Glu Glu His Pro Ser Ala His Glu Tyr Tyr Asp Pro Asn 
385                 390                 395                 400 


Asp Tyr Ile Gly Asp Ile His Gln Glu Met Asp Arg Glu Glu Leu Glu 
                405                 410                 415     


Leu Glu Glu Val Asp Leu Tyr Arg Met Asn Ser Gln Asp Lys Leu Gly 
            420                 425                 430         


Leu Thr Val Cys Tyr Arg Thr Asp Asp Glu Asp Asp Ile Gly Ile Tyr 
        435                 440                 445             


Ile Ser Glu Ile Asp Pro Asn Ser Ile Ala Ala Lys Asp Gly Arg Ile 
    450                 455                 460                 


Arg Glu Gly Asp Arg Ile Ile Gln Ile Asn Gly Ile Glu Val Gln Asn 
465                 470                 475                 480 


Arg Glu Glu Ala Val Ala Leu Leu Thr Ser Glu Glu Asn Lys Asn Phe 
                485                 490                 495     


Ser Leu Leu Ile Ala Arg Pro Glu Leu Gln Leu Asp Glu Gly Trp Met 
            500                 505                 510         


Asp Asp Asp Arg Asn Asp Phe Leu Asp Asp Leu His Met Asp Met Leu 
        515                 520                 525             


Glu Glu Gln His His Gln Ala Met Gln Phe Thr Ala Ser Val Leu Gln 
    530                 535                 540                 


Gln Lys Lys His Asp Glu Asp Gly Gly Thr Thr Asp Thr Ala Thr Ile 
545                 550                 555                 560 


Leu Ser Asn Gln His Glu Lys Asp Ser Gly Val Gly Arg Thr Asp Glu 
                565                 570                 575     


Ser Thr Arg Asn Asp Glu Ser Ser Glu Gln Glu Asn Asn Gly Asp Asp 
            580                 585                 590         


Ala Thr Ala Ser Ser Asn Pro Leu Ala Gly Gln Arg Lys Leu Thr Cys 
        595                 600                 605             


Ser Gln Asp Thr Leu Gly Ser Gly Asp Leu Pro Phe Ser Asn Glu Ser 
    610                 615                 620                 


Phe Ile Ser Ala Asp Cys Thr Asp Ala Asp Tyr Leu Gly Ile Pro Val 
625                 630                 635                 640 


Asp Glu Cys Glu Arg Phe Arg Glu Leu Leu Glu Leu Lys Cys Gln Val 
                645                 650                 655     


Lys Ser Ala Thr Pro Tyr Gly Leu Tyr Tyr Pro Ser Gly Pro Leu Asp 
            660                 665                 670         


Ala Gly Lys Ser Asp Pro Glu Ser Val Asp Lys Glu Leu Glu Leu Leu 
        675                 680                 685             


Asn Glu Glu Leu Arg Ser Ile Glu Leu Glu Cys Leu Ser Ile Val Arg 
    690                 695                 700                 


Ala His Lys Met Gln Gln Leu Lys Glu Gln Tyr Arg Glu Ser Trp Met 
705                 710                 715                 720 


Leu His Asn Ser Gly Phe Arg Asn Tyr Asn Thr Ser Ile Asp Val Arg 
                725                 730                 735     


Arg His Glu Leu Ser Asp Ile Thr Glu Leu Pro Glu Lys Ser Asp Lys 
            740                 745                 750         


Asp Ser Ser Ser Ala Tyr Asn Thr Gly Glu Ser Cys Arg Ser Thr Pro 
        755                 760                 765             


Leu Thr Leu Glu Ile Ser Pro Asp Asn Ser Leu Arg Arg Ala Ala Glu 
    770                 775                 780                 


Gly Ile Ser Cys Pro Ser Ser Glu Gly Ala Val Gly Thr Thr Glu Ala 
785                 790                 795                 800 


Tyr Gly Pro Ala Ser Lys Asn Leu Leu Ser Ile Thr Glu Asp Pro Glu 
                805                 810                 815     


Val Gly Thr Pro Thr Tyr Ser Pro Ser Leu Lys Glu Leu Asp Pro Asn 
            820                 825                 830         


Gln Pro Leu Glu Ser Lys Glu Arg Arg Ala Ser Asp Gly Ser Arg Ser 
        835                 840                 845             


Pro Thr Pro Ser Gln Lys Leu Gly Ser Ala Tyr Leu Pro Ser Tyr His 
    850                 855                 860                 


His Ser Pro Tyr Lys His Ala His Ile Pro Ala His Ala Gln His Tyr 
865                 870                 875                 880 


Gln Ser Tyr Met Gln Leu Ile Gln Gln Lys Ser Ala Val Glu Tyr Ala 
                885                 890                 895     


Gln Ser Gln Met Ser Leu Val Ser Met Cys Lys Asp Leu Ser Ser Pro 
            900                 905                 910         


Thr Pro Ser Glu Pro Arg Met Glu Trp Lys Val Lys Ile Arg Ser Asp 
        915                 920                 925             


Gly Thr Arg Tyr Ile Thr Lys Arg Pro Val Arg Asp Arg Leu Leu Arg 
    930                 935                 940                 


Glu Arg Ala Leu Lys Ile Arg Glu Glu Arg Ser Gly Met Thr Thr Asp 
945                 950                 955                 960 


Asp Asp Ala Val Ser Glu Met Lys Met Gly Arg Tyr Trp Ser Lys Glu 
                965                 970                 975     


Glu Arg Lys Gln His Leu Val Lys Ala Lys Glu Gln Arg Arg Arg Arg 
            980                 985                 990         


Glu Phe Met Met Gln Ser Arg Leu  Asp Cys Leu Lys Glu  Gln Gln Ala 
        995                 1000                 1005             


Ala Asp  Asp Arg Lys Glu Met  Asn Ile Leu Glu Leu  Ser His Lys 
    1010                 1015                 1020             


Lys Met  Met Lys Lys Arg Asn  Lys Lys Ile Phe Asp  Asn Trp Met 
    1025                 1030                 1035             


Thr Ile  Gln Glu Leu Leu Thr  His Gly Thr Lys Ser  Pro Asp Gly 
    1040                 1045                 1050             


Thr Arg  Val Tyr Asn Ser Phe  Leu Ser Val Thr Thr  Val 
    1055                 1060                 1065     


<210>  3603
<211>  373
<212>  PRT
<213>  homo sapiens

<400>  3603

Met Glu Asp Leu Asp Gln Ser Pro Leu Val Ser Ser Ser Asp Ser Pro 
1               5                   10                  15      


Pro Arg Pro Gln Pro Ala Phe Lys Tyr Gln Phe Val Arg Glu Pro Glu 
            20                  25                  30          


Asp Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp Glu Asp Glu Asp 
        35                  40                  45              


Leu Glu Glu Leu Glu Val Leu Glu Arg Lys Pro Ala Ala Gly Leu Ser 
    50                  55                  60                  


Ala Ala Pro Val Pro Thr Ala Pro Ala Ala Gly Ala Pro Leu Met Asp 
65                  70                  75                  80  


Phe Gly Asn Asp Phe Val Pro Pro Ala Pro Arg Gly Pro Leu Pro Ala 
                85                  90                  95      


Ala Pro Pro Val Ala Pro Glu Arg Gln Pro Ser Trp Asp Pro Ser Pro 
            100                 105                 110         


Val Ser Ser Thr Val Pro Ala Pro Ser Pro Leu Ser Ala Ala Ala Val 
        115                 120                 125             


Ser Pro Ser Lys Leu Pro Glu Asp Asp Glu Pro Pro Ala Arg Pro Pro 
    130                 135                 140                 


Pro Pro Pro Pro Ala Ser Val Ser Pro Gln Ala Glu Pro Val Trp Thr 
145                 150                 155                 160 


Pro Pro Ala Pro Ala Pro Ala Ala Pro Pro Ser Thr Pro Ala Ala Pro 
                165                 170                 175     


Lys Arg Arg Gly Ser Ser Gly Ser Val Val Val Asp Leu Leu Tyr Trp 
            180                 185                 190         


Arg Asp Ile Lys Lys Thr Gly Val Val Phe Gly Ala Ser Leu Phe Leu 
        195                 200                 205             


Leu Leu Ser Leu Thr Val Phe Ser Ile Val Ser Val Thr Ala Tyr Ile 
    210                 215                 220                 


Ala Leu Ala Leu Leu Ser Val Thr Ile Ser Phe Arg Ile Tyr Lys Gly 
225                 230                 235                 240 


Val Ile Gln Ala Ile Gln Lys Ser Asp Glu Gly His Pro Phe Arg Ala 
                245                 250                 255     


Tyr Leu Glu Ser Glu Val Ala Ile Ser Glu Glu Leu Val Gln Lys Tyr 
            260                 265                 270         


Ser Asn Ser Ala Leu Gly His Val Asn Cys Thr Ile Lys Glu Leu Arg 
        275                 280                 285             


Arg Leu Phe Leu Val Asp Asp Leu Val Asp Ser Leu Lys Phe Ala Val 
    290                 295                 300                 


Leu Met Trp Val Phe Thr Tyr Val Gly Ala Leu Phe Asn Gly Leu Thr 
305                 310                 315                 320 


Leu Leu Ile Leu Ala Leu Ile Ser Leu Phe Ser Val Pro Val Ile Tyr 
                325                 330                 335     


Glu Arg His Gln Ala Gln Ile Asp His Tyr Leu Gly Leu Ala Asn Lys 
            340                 345                 350         


Asn Val Lys Asp Ala Met Ala Lys Ile Gln Ala Lys Ile Pro Gly Leu 
        355                 360                 365             


Lys Arg Lys Ala Glu 
    370             


<210>  3604
<211>  1192
<212>  PRT
<213>  homo sapiens

<400>  3604

Met Glu Asp Leu Asp Gln Ser Pro Leu Val Ser Ser Ser Asp Ser Pro 
1               5                   10                  15      


Pro Arg Pro Gln Pro Ala Phe Lys Tyr Gln Phe Val Arg Glu Pro Glu 
            20                  25                  30          


Asp Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp Glu Asp Glu Asp 
        35                  40                  45              


Leu Glu Glu Leu Glu Val Leu Glu Arg Lys Pro Ala Ala Gly Leu Ser 
    50                  55                  60                  


Ala Ala Pro Val Pro Thr Ala Pro Ala Ala Gly Ala Pro Leu Met Asp 
65                  70                  75                  80  


Phe Gly Asn Asp Phe Val Pro Pro Ala Pro Arg Gly Pro Leu Pro Ala 
                85                  90                  95      


Ala Pro Pro Val Ala Pro Glu Arg Gln Pro Ser Trp Asp Pro Ser Pro 
            100                 105                 110         


Val Ser Ser Thr Val Pro Ala Pro Ser Pro Leu Ser Ala Ala Ala Val 
        115                 120                 125             


Ser Pro Ser Lys Leu Pro Glu Asp Asp Glu Pro Pro Ala Arg Pro Pro 
    130                 135                 140                 


Pro Pro Pro Pro Ala Ser Val Ser Pro Gln Ala Glu Pro Val Trp Thr 
145                 150                 155                 160 


Pro Pro Ala Pro Ala Pro Ala Ala Pro Pro Ser Thr Pro Ala Ala Pro 
                165                 170                 175     


Lys Arg Arg Gly Ser Ser Gly Ser Val Asp Glu Thr Leu Phe Ala Leu 
            180                 185                 190         


Pro Ala Ala Ser Glu Pro Val Ile Arg Ser Ser Ala Glu Asn Met Asp 
        195                 200                 205             


Leu Lys Glu Gln Pro Gly Asn Thr Ile Ser Ala Gly Gln Glu Asp Phe 
    210                 215                 220                 


Pro Ser Val Leu Leu Glu Thr Ala Ala Ser Leu Pro Ser Leu Ser Pro 
225                 230                 235                 240 


Leu Ser Ala Ala Ser Phe Lys Glu His Glu Tyr Leu Gly Asn Leu Ser 
                245                 250                 255     


Thr Val Leu Pro Thr Glu Gly Thr Leu Gln Glu Asn Val Ser Glu Ala 
            260                 265                 270         


Ser Lys Glu Val Ser Glu Lys Ala Lys Thr Leu Leu Ile Asp Arg Asp 
        275                 280                 285             


Leu Thr Glu Phe Ser Glu Leu Glu Tyr Ser Glu Met Gly Ser Ser Phe 
    290                 295                 300                 


Ser Val Ser Pro Lys Ala Glu Ser Ala Val Ile Val Ala Asn Pro Arg 
305                 310                 315                 320 


Glu Glu Ile Ile Val Lys Asn Lys Asp Glu Glu Glu Lys Leu Val Ser 
                325                 330                 335     


Asn Asn Ile Leu His Asn Gln Gln Glu Leu Pro Thr Ala Leu Thr Lys 
            340                 345                 350         


Leu Val Lys Glu Asp Glu Val Val Ser Ser Glu Lys Ala Lys Asp Ser 
        355                 360                 365             


Phe Asn Glu Lys Arg Val Ala Val Glu Ala Pro Met Arg Glu Glu Tyr 
    370                 375                 380                 


Ala Asp Phe Lys Pro Phe Glu Arg Val Trp Glu Val Lys Asp Ser Lys 
385                 390                 395                 400 


Glu Asp Ser Asp Met Leu Ala Ala Gly Gly Lys Ile Glu Ser Asn Leu 
                405                 410                 415     


Glu Ser Lys Val Asp Lys Lys Cys Phe Ala Asp Ser Leu Glu Gln Thr 
            420                 425                 430         


Asn His Glu Lys Asp Ser Glu Ser Ser Asn Asp Asp Thr Ser Phe Pro 
        435                 440                 445             


Ser Thr Pro Glu Gly Ile Lys Asp Arg Ser Gly Ala Tyr Ile Thr Cys 
    450                 455                 460                 


Ala Pro Phe Asn Pro Ala Ala Thr Glu Ser Ile Ala Thr Asn Ile Phe 
465                 470                 475                 480 


Pro Leu Leu Gly Asp Pro Thr Ser Glu Asn Lys Thr Asp Glu Lys Lys 
                485                 490                 495     


Ile Glu Glu Lys Lys Ala Gln Ile Val Thr Glu Lys Asn Thr Ser Thr 
            500                 505                 510         


Lys Thr Ser Asn Pro Phe Leu Val Ala Ala Gln Asp Ser Glu Thr Asp 
        515                 520                 525             


Tyr Val Thr Thr Asp Asn Leu Thr Lys Val Thr Glu Glu Val Val Ala 
    530                 535                 540                 


Asn Met Pro Glu Gly Leu Thr Pro Asp Leu Val Gln Glu Ala Cys Glu 
545                 550                 555                 560 


Ser Glu Leu Asn Glu Val Thr Gly Thr Lys Ile Ala Tyr Glu Thr Lys 
                565                 570                 575     


Met Asp Leu Val Gln Thr Ser Glu Val Met Gln Glu Ser Leu Tyr Pro 
            580                 585                 590         


Ala Ala Gln Leu Cys Pro Ser Phe Glu Glu Ser Glu Ala Thr Pro Ser 
        595                 600                 605             


Pro Val Leu Pro Asp Ile Val Met Glu Ala Pro Leu Asn Ser Ala Val 
    610                 615                 620                 


Pro Ser Ala Gly Ala Ser Val Ile Gln Pro Ser Ser Ser Pro Leu Glu 
625                 630                 635                 640 


Ala Ser Ser Val Asn Tyr Glu Ser Ile Lys His Glu Pro Glu Asn Pro 
                645                 650                 655     


Pro Pro Tyr Glu Glu Ala Met Ser Val Ser Leu Lys Lys Val Ser Gly 
            660                 665                 670         


Ile Lys Glu Glu Ile Lys Glu Pro Glu Asn Ile Asn Ala Ala Leu Gln 
        675                 680                 685             


Glu Thr Glu Ala Pro Tyr Ile Ser Ile Ala Cys Asp Leu Ile Lys Glu 
    690                 695                 700                 


Thr Lys Leu Ser Ala Glu Pro Ala Pro Asp Phe Ser Asp Tyr Ser Glu 
705                 710                 715                 720 


Met Ala Lys Val Glu Gln Pro Val Pro Asp His Ser Glu Leu Val Glu 
                725                 730                 735     


Asp Ser Ser Pro Asp Ser Glu Pro Val Asp Leu Phe Ser Asp Asp Ser 
            740                 745                 750         


Ile Pro Asp Val Pro Gln Lys Gln Asp Glu Thr Val Met Leu Val Lys 
        755                 760                 765             


Glu Ser Leu Thr Glu Thr Ser Phe Glu Ser Met Ile Glu Tyr Glu Asn 
    770                 775                 780                 


Lys Glu Lys Leu Ser Ala Leu Pro Pro Glu Gly Gly Lys Pro Tyr Leu 
785                 790                 795                 800 


Glu Ser Phe Lys Leu Ser Leu Asp Asn Thr Lys Asp Thr Leu Leu Pro 
                805                 810                 815     


Asp Glu Val Ser Thr Leu Ser Lys Lys Glu Lys Ile Pro Leu Gln Met 
            820                 825                 830         


Glu Glu Leu Ser Thr Ala Val Tyr Ser Asn Asp Asp Leu Phe Ile Ser 
        835                 840                 845             


Lys Glu Ala Gln Ile Arg Glu Thr Glu Thr Phe Ser Asp Ser Ser Pro 
    850                 855                 860                 


Ile Glu Ile Ile Asp Glu Phe Pro Thr Leu Ile Ser Ser Lys Thr Asp 
865                 870                 875                 880 


Ser Phe Ser Lys Leu Ala Arg Glu Tyr Thr Asp Leu Glu Val Ser His 
                885                 890                 895     


Lys Ser Glu Ile Ala Asn Ala Pro Asp Gly Ala Gly Ser Leu Pro Cys 
            900                 905                 910         


Thr Glu Leu Pro His Asp Leu Ser Leu Lys Asn Ile Gln Pro Lys Val 
        915                 920                 925             


Glu Glu Lys Ile Ser Phe Ser Asp Asp Phe Ser Lys Asn Gly Ser Ala 
    930                 935                 940                 


Thr Ser Lys Val Leu Leu Leu Pro Pro Asp Val Ser Ala Leu Ala Thr 
945                 950                 955                 960 


Gln Ala Glu Ile Glu Ser Ile Val Lys Pro Lys Val Leu Val Lys Glu 
                965                 970                 975     


Ala Glu Lys Lys Leu Pro Ser Asp Thr Glu Lys Glu Asp Arg Ser Pro 
            980                 985                 990         


Ser Ala Ile Phe Ser Ala Glu Leu  Ser Lys Thr Ser Val  Val Asp Leu 
        995                 1000                 1005             


Leu Tyr  Trp Arg Asp Ile Lys  Lys Thr Gly Val Val  Phe Gly Ala 
    1010                 1015                 1020             


Ser Leu  Phe Leu Leu Leu Ser  Leu Thr Val Phe Ser  Ile Val Ser 
    1025                 1030                 1035             


Val Thr  Ala Tyr Ile Ala Leu  Ala Leu Leu Ser Val  Thr Ile Ser 
    1040                 1045                 1050             


Phe Arg  Ile Tyr Lys Gly Val  Ile Gln Ala Ile Gln  Lys Ser Asp 
    1055                 1060                 1065             


Glu Gly  His Pro Phe Arg Ala  Tyr Leu Glu Ser Glu  Val Ala Ile 
    1070                 1075                 1080             


Ser Glu  Glu Leu Val Gln Lys  Tyr Ser Asn Ser Ala  Leu Gly His 
    1085                 1090                 1095             


Val Asn  Cys Thr Ile Lys Glu  Leu Arg Arg Leu Phe  Leu Val Asp 
    1100                 1105                 1110             


Asp Leu  Val Asp Ser Leu Lys  Phe Ala Val Leu Met  Trp Val Phe 
    1115                 1120                 1125             


Thr Tyr  Val Gly Ala Leu Phe  Asn Gly Leu Thr Leu  Leu Ile Leu 
    1130                 1135                 1140             


Ala Leu  Ile Ser Leu Phe Ser  Val Pro Val Ile Tyr  Glu Arg His 
    1145                 1150                 1155             


Gln Ala  Gln Ile Asp His Tyr  Leu Gly Leu Ala Asn  Lys Asn Val 
    1160                 1165                 1170             


Lys Asp  Ala Met Ala Lys Ile  Gln Ala Lys Ile Pro  Gly Leu Lys 
    1175                 1180                 1185             


Arg Lys  Ala Glu 
    1190         


<210>  3605
<211>  534
<212>  PRT
<213>  homo sapiens

<400>  3605

Met Leu Arg Arg Arg Gly Ser Pro Gly Met Gly Val His Val Gly Ala 
1               5                   10                  15      


Ala Leu Gly Ala Leu Trp Phe Cys Leu Thr Gly Ala Leu Glu Val Gln 
            20                  25                  30          


Val Pro Glu Asp Pro Val Val Ala Leu Val Gly Thr Asp Ala Thr Leu 
        35                  40                  45              


Cys Cys Ser Phe Ser Pro Glu Pro Gly Phe Ser Leu Ala Gln Leu Asn 
    50                  55                  60                  


Leu Ile Trp Gln Leu Thr Asp Thr Lys Gln Leu Val His Ser Phe Ala 
65                  70                  75                  80  


Glu Gly Gln Asp Gln Gly Ser Ala Tyr Ala Asn Arg Thr Ala Leu Phe 
                85                  90                  95      


Pro Asp Leu Leu Ala Gln Gly Asn Ala Ser Leu Arg Leu Gln Arg Val 
            100                 105                 110         


Arg Val Ala Asp Glu Gly Ser Phe Thr Cys Phe Val Ser Ile Arg Asp 
        115                 120                 125             


Phe Gly Ser Ala Ala Val Ser Leu Gln Val Ala Ala Pro Tyr Ser Lys 
    130                 135                 140                 


Pro Ser Met Thr Leu Glu Pro Asn Lys Asp Leu Arg Pro Gly Asp Thr 
145                 150                 155                 160 


Val Thr Ile Thr Cys Ser Ser Tyr Gln Gly Tyr Pro Glu Ala Glu Val 
                165                 170                 175     


Phe Trp Gln Asp Gly Gln Gly Val Pro Leu Thr Gly Asn Val Thr Thr 
            180                 185                 190         


Ser Gln Met Ala Asn Glu Gln Gly Leu Phe Asp Val His Ser Ile Leu 
        195                 200                 205             


Arg Val Val Leu Gly Ala Asn Gly Thr Tyr Ser Cys Leu Val Arg Asn 
    210                 215                 220                 


Pro Val Leu Gln Gln Asp Ala His Ser Ser Val Thr Ile Thr Pro Gln 
225                 230                 235                 240 


Arg Ser Pro Thr Gly Ala Val Glu Val Gln Val Pro Glu Asp Pro Val 
                245                 250                 255     


Val Ala Leu Val Gly Thr Asp Ala Thr Leu Arg Cys Ser Phe Ser Pro 
            260                 265                 270         


Glu Pro Gly Phe Ser Leu Ala Gln Leu Asn Leu Ile Trp Gln Leu Thr 
        275                 280                 285             


Asp Thr Lys Gln Leu Val His Ser Phe Thr Glu Gly Arg Asp Gln Gly 
    290                 295                 300                 


Ser Ala Tyr Ala Asn Arg Thr Ala Leu Phe Pro Asp Leu Leu Ala Gln 
305                 310                 315                 320 


Gly Asn Ala Ser Leu Arg Leu Gln Arg Val Arg Val Ala Asp Glu Gly 
                325                 330                 335     


Ser Phe Thr Cys Phe Val Ser Ile Arg Asp Phe Gly Ser Ala Ala Val 
            340                 345                 350         


Ser Leu Gln Val Ala Ala Pro Tyr Ser Lys Pro Ser Met Thr Leu Glu 
        355                 360                 365             


Pro Asn Lys Asp Leu Arg Pro Gly Asp Thr Val Thr Ile Thr Cys Ser 
    370                 375                 380                 


Ser Tyr Arg Gly Tyr Pro Glu Ala Glu Val Phe Trp Gln Asp Gly Gln 
385                 390                 395                 400 


Gly Val Pro Leu Thr Gly Asn Val Thr Thr Ser Gln Met Ala Asn Glu 
                405                 410                 415     


Gln Gly Leu Phe Asp Val His Ser Val Leu Arg Val Val Leu Gly Ala 
            420                 425                 430         


Asn Gly Thr Tyr Ser Cys Leu Val Arg Asn Pro Val Leu Gln Gln Asp 
        435                 440                 445             


Ala His Gly Ser Val Thr Ile Thr Gly Gln Pro Met Thr Phe Pro Pro 
    450                 455                 460                 


Glu Ala Leu Trp Val Thr Val Gly Leu Ser Val Cys Leu Ile Ala Leu 
465                 470                 475                 480 


Leu Val Ala Leu Ala Phe Val Cys Trp Arg Lys Ile Lys Gln Ser Cys 
                485                 490                 495     


Glu Glu Glu Asn Ala Gly Ala Glu Asp Gln Asp Gly Glu Gly Glu Gly 
            500                 505                 510         


Ser Lys Thr Ala Leu Gln Pro Leu Lys His Ser Asp Ser Lys Glu Asp 
        515                 520                 525             


Asp Gly Gln Glu Ile Ala 
    530                 


<210>  3606
<211>  410
<212>  PRT
<213>  homo sapiens

<400>  3606

Met Glu Gln Lys Pro Ser Lys Val Glu Cys Gly Ser Asp Pro Glu Glu 
1               5                   10                  15      


Asn Ser Ala Arg Ser Pro Asp Gly Lys Arg Lys Arg Lys Asn Gly Gln 
            20                  25                  30          


Cys Ser Leu Lys Thr Ser Met Ser Gly Tyr Ile Pro Ser Tyr Leu Asp 
        35                  40                  45              


Lys Asp Glu Gln Cys Val Val Cys Gly Asp Lys Ala Thr Gly Tyr His 
    50                  55                  60                  


Tyr Arg Cys Ile Thr Cys Glu Gly Cys Lys Gly Phe Phe Arg Arg Thr 
65                  70                  75                  80  


Ile Gln Lys Asn Leu His Pro Thr Tyr Ser Cys Lys Tyr Asp Ser Cys 
                85                  90                  95      


Cys Val Ile Asp Lys Ile Thr Arg Asn Gln Cys Gln Leu Cys Arg Phe 
            100                 105                 110         


Lys Lys Cys Ile Ala Val Gly Met Ala Met Asp Leu Val Leu Asp Asp 
        115                 120                 125             


Ser Lys Arg Val Ala Lys Arg Lys Leu Ile Glu Gln Asn Arg Glu Arg 
    130                 135                 140                 


Arg Arg Lys Glu Glu Met Ile Arg Ser Leu Gln Gln Arg Pro Glu Pro 
145                 150                 155                 160 


Thr Pro Glu Glu Trp Asp Leu Ile His Ile Ala Thr Glu Ala His Arg 
                165                 170                 175     


Ser Thr Asn Ala Gln Gly Ser His Trp Lys Gln Arg Arg Lys Phe Leu 
            180                 185                 190         


Pro Asp Asp Ile Gly Gln Ser Pro Ile Val Ser Met Pro Asp Gly Asp 
        195                 200                 205             


Lys Val Asp Leu Glu Ala Phe Ser Glu Phe Thr Lys Ile Ile Thr Pro 
    210                 215                 220                 


Ala Ile Thr Arg Val Val Asp Phe Ala Lys Lys Leu Pro Met Phe Ser 
225                 230                 235                 240 


Glu Leu Pro Cys Glu Asp Gln Ile Ile Leu Leu Lys Gly Cys Cys Met 
                245                 250                 255     


Glu Ile Met Ser Leu Arg Ala Ala Val Arg Tyr Asp Pro Glu Ser Asp 
            260                 265                 270         


Thr Leu Thr Leu Ser Gly Glu Met Ala Val Lys Arg Glu Gln Leu Lys 
        275                 280                 285             


Asn Gly Gly Leu Gly Val Val Ser Asp Ala Ile Phe Glu Leu Gly Lys 
    290                 295                 300                 


Ser Leu Ser Ala Phe Asn Leu Asp Asp Thr Glu Val Ala Leu Leu Gln 
305                 310                 315                 320 


Ala Val Leu Leu Met Ser Thr Asp Arg Ser Gly Leu Leu Cys Val Asp 
                325                 330                 335     


Lys Ile Glu Lys Ser Gln Glu Ala Tyr Leu Leu Ala Phe Glu His Tyr 
            340                 345                 350         


Val Asn His Arg Lys His Asn Ile Pro His Phe Trp Pro Lys Leu Leu 
        355                 360                 365             


Met Lys Val Thr Asp Leu Arg Met Ile Gly Ala Cys His Ala Ser Arg 
    370                 375                 380                 


Phe Leu His Met Lys Val Glu Cys Pro Thr Glu Leu Phe Pro Pro Leu 
385                 390                 395                 400 


Phe Leu Glu Val Phe Glu Asp Gln Glu Val 
                405                 410 


<210>  3607
<211>  955
<212>  PRT
<213>  homo sapiens

<400>  3607

Met Ser Lys Thr Asn Lys Ser Lys Ser Gly Ser Arg Ser Ser Arg Ser 
1               5                   10                  15      


Arg Ser Ala Ser Arg Ser Arg Ser Arg Ser Phe Ser Lys Ser Arg Ser 
            20                  25                  30          


Arg Ser Arg Ser Leu Ser Arg Ser Arg Lys Arg Arg Leu Ser Ser Arg 
        35                  40                  45              


Ser Arg Ser Arg Ser Tyr Ser Pro Ala His Asn Arg Glu Arg Asn His 
    50                  55                  60                  


Pro Arg Val Tyr Gln Asn Arg Asp Phe Arg Gly His Asn Arg Gly Tyr 
65                  70                  75                  80  


Arg Arg Pro Tyr Tyr Phe Arg Gly Arg Asn Arg Gly Phe Tyr Pro Trp 
                85                  90                  95      


Gly Gln Tyr Asn Arg Gly Gly Tyr Gly Asn Tyr Arg Ser Asn Trp Gln 
            100                 105                 110         


Asn Tyr Arg Gln Ala Tyr Ser Pro Arg Arg Gly Arg Ser Arg Ser Arg 
        115                 120                 125             


Ser Pro Lys Arg Arg Ser Pro Ser Pro Arg Ser Arg Ser His Ser Arg 
    130                 135                 140                 


Asn Ser Asp Lys Ser Ser Ser Asp Arg Ser Arg Arg Ser Ser Ser Ser 
145                 150                 155                 160 


Arg Ser Ser Ser Asn His Ser Arg Val Glu Ser Ser Lys Arg Lys Ser 
                165                 170                 175     


Ala Lys Glu Lys Lys Ser Ser Ser Lys Asp Ser Arg Pro Ser Gln Ala 
            180                 185                 190         


Ala Gly Asp Asn Gln Gly Asp Glu Ala Lys Glu Gln Thr Phe Ser Gly 
        195                 200                 205             


Gly Thr Ser Gln Asp Thr Lys Ala Ser Glu Ser Ser Lys Pro Trp Pro 
    210                 215                 220                 


Asp Ala Thr Tyr Gly Thr Gly Ser Ala Ser Arg Ala Ser Ala Val Ser 
225                 230                 235                 240 


Glu Leu Ser Pro Arg Glu Arg Ser Pro Ala Leu Lys Ser Pro Leu Gln 
                245                 250                 255     


Ser Val Val Val Arg Arg Arg Ser Pro Arg Pro Ser Pro Val Pro Lys 
            260                 265                 270         


Pro Ser Pro Pro Leu Ser Ser Thr Ser Gln Met Gly Ser Thr Leu Pro 
        275                 280                 285             


Ser Gly Ala Gly Tyr Gln Ser Gly Thr His Gln Gly Gln Phe Asp His 
    290                 295                 300                 


Gly Ser Gly Ser Leu Ser Pro Ser Lys Lys Ser Pro Val Gly Lys Ser 
305                 310                 315                 320 


Pro Pro Ser Thr Gly Ser Thr Tyr Gly Ser Ser Gln Lys Glu Glu Ser 
                325                 330                 335     


Ala Ala Ser Gly Gly Ala Ala Tyr Thr Lys Arg Tyr Leu Glu Glu Gln 
            340                 345                 350         


Lys Thr Glu Asn Gly Lys Asp Lys Glu Gln Lys Gln Thr Asn Thr Asp 
        355                 360                 365             


Lys Glu Lys Ile Lys Glu Lys Gly Ser Phe Ser Asp Thr Gly Leu Gly 
    370                 375                 380                 


Asp Gly Lys Met Lys Ser Asp Ser Phe Ala Pro Lys Thr Asp Ser Glu 
385                 390                 395                 400 


Lys Pro Phe Arg Gly Ser Gln Ser Pro Lys Arg Tyr Lys Leu Arg Asp 
                405                 410                 415     


Asp Phe Glu Lys Lys Met Ala Asp Phe His Lys Glu Glu Met Asp Asp 
            420                 425                 430         


Gln Asp Lys Asp Lys Ala Lys Gly Arg Lys Glu Ser Glu Phe Asp Asp 
        435                 440                 445             


Glu Pro Lys Phe Met Ser Lys Val Ile Gly Ala Asn Lys Asn Gln Glu 
    450                 455                 460                 


Glu Glu Lys Ser Gly Lys Trp Glu Gly Leu Val Tyr Ala Pro Pro Gly 
465                 470                 475                 480 


Lys Glu Lys Gln Arg Lys Thr Glu Glu Leu Glu Glu Glu Ser Phe Pro 
                485                 490                 495     


Glu Arg Ser Lys Lys Glu Asp Arg Gly Lys Arg Ser Glu Gly Gly His 
            500                 505                 510         


Arg Gly Phe Val Pro Glu Lys Asn Phe Arg Val Thr Ala Tyr Lys Ala 
        515                 520                 525             


Val Gln Glu Lys Ser Ser Ser Pro Pro Pro Arg Lys Thr Ser Glu Ser 
    530                 535                 540                 


Arg Asp Lys Leu Gly Ala Lys Gly Asp Phe Pro Thr Gly Lys Ser Ser 
545                 550                 555                 560 


Phe Ser Ile Thr Arg Glu Ala Gln Val Asn Val Arg Met Asp Ser Phe 
                565                 570                 575     


Asp Glu Asp Leu Ala Arg Pro Ser Gly Leu Leu Ala Gln Glu Arg Lys 
            580                 585                 590         


Leu Cys Arg Asp Leu Val His Ser Asn Lys Lys Glu Gln Glu Phe Arg 
        595                 600                 605             


Ser Ile Phe Gln His Ile Gln Ser Ala Gln Ser Gln Arg Ser Pro Ser 
    610                 615                 620                 


Glu Leu Phe Ala Gln His Ile Val Thr Ile Val His His Val Lys Glu 
625                 630                 635                 640 


His His Phe Gly Ser Ser Gly Met Thr Leu His Glu Arg Phe Thr Lys 
                645                 650                 655     


Tyr Leu Lys Arg Gly Thr Glu Gln Glu Ala Ala Lys Asn Lys Lys Ser 
            660                 665                 670         


Pro Glu Ile His Arg Arg Ile Asp Ile Ser Pro Ser Thr Phe Arg Lys 
        675                 680                 685             


His Gly Leu Ala His Asp Glu Met Lys Ser Pro Arg Glu Pro Gly Tyr 
    690                 695                 700                 


Lys Ala Glu Gly Lys Tyr Lys Asp Asp Pro Val Asp Leu Arg Leu Asp 
705                 710                 715                 720 


Ile Glu Arg Arg Lys Lys His Lys Glu Arg Asp Leu Lys Arg Gly Lys 
                725                 730                 735     


Ser Arg Glu Ser Val Asp Ser Arg Asp Ser Ser His Ser Arg Glu Arg 
            740                 745                 750         


Ser Ala Glu Lys Thr Glu Lys Thr His Lys Gly Ser Lys Lys Gln Lys 
        755                 760                 765             


Lys His Arg Arg Ala Arg Asp Arg Ser Arg Ser Ser Ser Ser Ser Ser 
    770                 775                 780                 


Gln Ser Ser His Ser Tyr Lys Ala Glu Glu Tyr Thr Glu Glu Thr Glu 
785                 790                 795                 800 


Glu Arg Glu Glu Ser Thr Thr Gly Phe Asp Lys Ser Arg Leu Gly Thr 
                805                 810                 815     


Lys Asp Phe Val Gly Pro Ser Glu Arg Gly Gly Gly Arg Ala Arg Gly 
            820                 825                 830         


Thr Phe Gln Phe Arg Ala Arg Gly Arg Gly Trp Gly Arg Gly Asn Tyr 
        835                 840                 845             


Ser Gly Asn Asn Asn Asn Asn Ser Asn Asn Asp Phe Gln Lys Arg Asn 
    850                 855                 860                 


Arg Glu Glu Glu Trp Asp Pro Glu Tyr Thr Pro Lys Ser Lys Lys Tyr 
865                 870                 875                 880 


Tyr Leu His Asp Asp Arg Glu Gly Glu Gly Ser Asp Lys Trp Val Ser 
                885                 890                 895     


Arg Gly Arg Gly Arg Gly Ala Phe Pro Arg Gly Arg Gly Arg Phe Met 
            900                 905                 910         


Phe Arg Lys Ser Ser Thr Ser Pro Lys Trp Ala His Asp Lys Phe Ser 
        915                 920                 925             


Gly Glu Glu Gly Glu Ile Glu Asp Asp Glu Ser Gly Thr Glu Asn Arg 
    930                 935                 940                 


Glu Glu Lys Asp Asn Ile Gln Pro Thr Thr Glu 
945                 950                 955 


<210>  3608
<211>  161
<212>  PRT
<213>  homo sapiens

<400>  3608

Met Asn Leu Ala Ile Ser Ile Ala Leu Leu Leu Thr Val Leu Gln Val 
1               5                   10                  15      


Ser Arg Gly Gln Lys Val Thr Ser Leu Thr Ala Cys Leu Val Asp Gln 
            20                  25                  30          


Ser Leu Arg Leu Asp Cys Arg His Glu Asn Thr Ser Ser Ser Pro Ile 
        35                  40                  45              


Gln Tyr Glu Phe Ser Leu Thr Arg Glu Thr Lys Lys His Val Leu Phe 
    50                  55                  60                  


Gly Thr Val Gly Val Pro Glu His Thr Tyr Arg Ser Arg Thr Asn Phe 
65                  70                  75                  80  


Thr Ser Lys Tyr Asn Met Lys Val Leu Tyr Leu Ser Ala Phe Thr Ser 
                85                  90                  95      


Lys Asp Glu Gly Thr Tyr Thr Cys Ala Leu His His Ser Gly His Ser 
            100                 105                 110         


Pro Pro Ile Ser Ser Gln Asn Val Thr Val Leu Arg Asp Lys Leu Val 
        115                 120                 125             


Lys Cys Glu Gly Ile Ser Leu Leu Ala Gln Asn Thr Ser Trp Leu Leu 
    130                 135                 140                 


Leu Leu Leu Leu Ser Leu Ser Leu Leu Gln Ala Thr Asp Phe Met Ser 
145                 150                 155                 160 


Leu 
    


<210>  3609
<211>  211
<212>  PRT
<213>  homo sapiens

<400>  3609

Met Thr Pro Trp Leu Gly Leu Ile Val Leu Leu Gly Ser Trp Ser Leu 
1               5                   10                  15      


Gly Asp Trp Gly Ala Glu Ala Cys Thr Cys Ser Pro Ser His Pro Gln 
            20                  25                  30          


Asp Ala Phe Cys Asn Ser Asp Ile Val Ile Arg Ala Lys Val Val Gly 
        35                  40                  45              


Lys Lys Leu Val Lys Glu Gly Pro Phe Gly Thr Leu Val Tyr Thr Ile 
    50                  55                  60                  


Lys Gln Met Lys Met Tyr Arg Gly Phe Thr Lys Met Pro His Val Gln 
65                  70                  75                  80  


Tyr Ile His Thr Glu Ala Ser Glu Ser Leu Cys Gly Leu Lys Leu Glu 
                85                  90                  95      


Val Asn Lys Tyr Gln Tyr Leu Leu Thr Gly Arg Val Tyr Asp Gly Lys 
            100                 105                 110         


Met Tyr Thr Gly Leu Cys Asn Phe Val Glu Arg Trp Asp Gln Leu Thr 
        115                 120                 125             


Leu Ser Gln Arg Lys Gly Leu Asn Tyr Arg Tyr His Leu Gly Cys Asn 
    130                 135                 140                 


Cys Lys Ile Lys Ser Cys Tyr Tyr Leu Pro Cys Phe Val Thr Ser Lys 
145                 150                 155                 160 


Asn Glu Cys Leu Trp Thr Asp Met Leu Ser Asn Phe Gly Tyr Pro Gly 
                165                 170                 175     


Tyr Gln Ser Lys His Tyr Ala Cys Ile Arg Gln Lys Gly Gly Tyr Cys 
            180                 185                 190         


Ser Trp Tyr Arg Gly Trp Ala Pro Pro Asp Lys Ser Ile Ile Asn Ala 
        195                 200                 205             


Thr Asp Pro 
    210     


<210>  3610
<211>  1045
<212>  PRT
<213>  homo sapiens

<400>  3610

Met Glu Ala Lys Val Arg Pro Ser Arg Arg Ser Arg Ala Gln Arg Asp 
1               5                   10                  15      


Arg Gly Arg Arg Arg Glu Ala Ala Arg Asp Ala Arg Ala Gln Ser Pro 
            20                  25                  30          


Ser Ser Gly Asp Glu Pro Glu Pro Ser Pro Gly Lys Glu Asn Ala Gly 
        35                  40                  45              


Leu Arg Gly Ala Pro Pro Arg Gly Ala Ala Pro Ala Pro Arg Thr Ala 
    50                  55                  60                  


Arg Pro Pro Arg Arg Arg Arg Arg Glu Ser Ser Ser Gln Glu Glu Glu 
65                  70                  75                  80  


Val Ile Asp Gly Phe Ala Ile Ala Ser Phe Ser Thr Leu Glu Ala Leu 
                85                  90                  95      


Glu Lys Asp Met Ala Leu Lys Pro His Glu Arg Lys Glu Lys Trp Glu 
            100                 105                 110         


Arg Arg Leu Ile Lys Lys Pro Arg Glu Ser Glu Thr Cys Pro Pro Ala 
        115                 120                 125             


Glu Pro Ser Glu Asn Arg Arg Pro Leu Glu Ala Gly Ser Pro Gly Gln 
    130                 135                 140                 


Asp Leu Glu Pro Ala Cys Asp Gly Ala Arg Lys Val Pro Leu Gln Pro 
145                 150                 155                 160 


Ser Lys Gln Met Lys Val Thr Val Ser Lys Gly Gly Asp Arg Asp Ser 
                165                 170                 175     


Asp Asp Asp Ser Val Leu Glu Ala Thr Ser Ser Arg Asp Pro Leu Ser 
            180                 185                 190         


Asp Ser Ser Ala His Ala Val Ser Gly Arg Gly Tyr Ser Cys Asp Ser 
        195                 200                 205             


Glu Ser Gly Pro Asp Asp Lys Ala Ser Val Gly Ser Glu Lys Leu Phe 
    210                 215                 220                 


Ala Pro Gly Thr Asp Lys Gly Pro Ala Leu Glu Lys Ser Glu Ala Lys 
225                 230                 235                 240 


Ala Gly Pro Val Pro Lys Val Ser Gly Leu Glu Arg Ser Arg Glu Leu 
                245                 250                 255     


Ser Ala Glu Ser Phe Leu Pro Thr Ala Ser Pro Ala Pro His Ala Ala 
            260                 265                 270         


Pro Cys Pro Gly Pro Pro Pro Gly Ser Arg Ala Asn Pro Leu Val Lys 
        275                 280                 285             


Lys Glu Pro Pro Ala Pro His Arg His Thr Pro Gln Pro Pro Pro Pro 
    290                 295                 300                 


Gln Pro Arg Gly Leu Leu Pro Thr His Val Pro Ala Ser Leu Gly Ala 
305                 310                 315                 320 


Phe Ala Gly His Ser Gln Ala Ala Ala Asn Gly Leu His Gly Leu Ser 
                325                 330                 335     


Arg Ser Ser Ser Ala Pro Leu Gly Leu Gly Lys His Val Ser Leu Ser 
            340                 345                 350         


Pro His Gly Pro Gly Pro His Leu Ser Thr Ser His Leu Ala Leu Arg 
        355                 360                 365             


Ser Gln Ala Gln His Gln Leu His Ala Ala Met Phe Ala Ala Pro Pro 
    370                 375                 380                 


Thr Leu Pro Pro Pro Pro Ala Leu Pro Ala Ser Ser Leu Val Leu Pro 
385                 390                 395                 400 


Gly His Pro Ala Asp His Glu Leu Leu Arg Gln Glu Leu Asn Thr Arg 
                405                 410                 415     


Phe Leu Val Gln Ser Ala Glu Arg Pro Gly Ala Ser Leu Gly Pro Gly 
            420                 425                 430         


Ala Leu Leu Arg Ala Glu Phe His Gln His Gln His Thr His Gln His 
        435                 440                 445             


Thr His Gln His Thr His Gln His Gln His Thr Phe Ala Pro Phe Pro 
    450                 455                 460                 


Ala Gly Leu Pro Pro Thr Pro Pro Ala Ala Pro Pro Pro Phe Asp Lys 
465                 470                 475                 480 


Tyr Ala Pro Lys Leu Asp Ser Pro Tyr Phe Arg His Ser Ser Val Ser 
                485                 490                 495     


Phe Phe Pro Ser Phe Pro Pro Ala Ile Pro Gly Leu Pro Thr Leu Leu 
            500                 505                 510         


Pro His Pro Gly Pro Phe Gly Ser Leu Gln Gly Ala Phe Gln Pro Lys 
        515                 520                 525             


Val Ser Asp Pro Tyr Arg Ala Val Val Lys Val Ser Thr Cys Trp Glu 
    530                 535                 540                 


Gly Pro Trp Gln Gly Arg Thr Leu Val Pro Pro Gly Arg Pro Arg Gly 
545                 550                 555                 560 


Ala Arg Asp Ser Arg Ser Leu Gln Lys Thr Trp Val Gly Val Ala Pro 
                565                 570                 575     


Ala Pro Leu Ser Ala Ser Ile Leu Ser Gln Lys Pro Gly Arg Trp Cys 
            580                 585                 590         


Ala Val His Val Gln Ile Ala Trp Gln Ile Tyr Arg His Gln Gln Lys 
        595                 600                 605             


Ile Lys Glu Met Gln Leu Asp Pro His Lys Leu Glu Val Gly Ala Lys 
    610                 615                 620                 


Leu Asp Leu Phe Gly Arg Pro Pro Ala Pro Gly Val Phe Ala Gly Phe 
625                 630                 635                 640 


His Tyr Pro Gln Asp Leu Ala Arg Pro Leu Phe Pro Ser Thr Gly Ala 
                645                 650                 655     


Ala His Pro Ala Ser Asn Pro Phe Gly Pro Ser Ala His Pro Gly Ser 
            660                 665                 670         


Phe Leu Pro Thr Gly Pro Leu Thr Asp Pro Phe Ser Arg Pro Ser Thr 
        675                 680                 685             


Phe Gly Gly Leu Gly Ser Leu Ser Ser His Ala Phe Gly Gly Leu Gly 
    690                 695                 700                 


Ser His Ala Leu Ala Pro Gly Gly Ser Ile Phe Ala Pro Lys Glu Gly 
705                 710                 715                 720 


Ser Ser Val His Gly Leu Pro Ser Pro His Glu Ala Trp Asn Arg Leu 
                725                 730                 735     


His Arg Ala Pro Pro Ser Phe Pro Ala Pro Pro Pro Trp Pro Lys Ser 
            740                 745                 750         


Val Asp Ala Glu Arg Val Ser Ala Leu Thr Asn His Asp Arg Glu Pro 
        755                 760                 765             


Asp Asn Gly Lys Glu Glu Gln Glu Arg Asp Leu Leu Glu Lys Thr Arg 
    770                 775                 780                 


Leu Leu Ser Arg Ala Ser Pro Ala Thr Pro Ala Gly His Pro Val Ser 
785                 790                 795                 800 


Gly Leu Leu Leu Arg Ala Gln Ser Glu Leu Gly Arg Ser Gly Ala Pro 
                805                 810                 815     


Ala Glu Arg Glu Ala Glu Pro Arg Val Lys Glu Ser Arg Ser Pro Ala 
            820                 825                 830         


Lys Glu Glu Ala Ala Lys Met Pro Ala Arg Ala Ser Pro Pro His Ser 
        835                 840                 845             


Lys Ala Ala Pro Gly Asp Val Lys Val Lys Glu Glu Arg Gly Glu Asp 
    850                 855                 860                 


Glu Ala Ser Glu Pro Pro Ala Gly Gly Leu His Pro Ala Pro Leu Gln 
865                 870                 875                 880 


Leu Gly Leu Gly Arg Glu Arg Leu Gly Ala Pro Gly Phe Ala Trp Glu 
                885                 890                 895     


Pro Phe Arg Gly Leu Glu Leu Pro Arg Arg Ala Phe Pro Ala Ala Ala 
            900                 905                 910         


Pro Ala Pro Gly Ser Ala Ala Leu Leu Glu Pro Pro Glu Arg Pro Tyr 
        915                 920                 925             


Arg Asp Arg Glu Pro His Gly Tyr Ser Pro Glu Arg Leu Arg Gly Glu 
    930                 935                 940                 


Leu Glu Arg Ala Arg Ala Pro His Leu Pro Pro Ala Ala Pro Ala Leu 
945                 950                 955                 960 


Asp Gly Ala Leu Leu Pro Ser Leu Gly Ala Leu His Phe Pro Arg Leu 
                965                 970                 975     


Ser Pro Ala Ala Leu His Asn Gly Leu Leu Ala Arg Thr Pro Pro Ala 
            980                 985                 990         


Ala Ala Ala Leu Gly Ala Pro Pro  Pro Leu Val Thr Ala  Ala Gly Pro 
        995                 1000                 1005             


Pro Thr  Pro Pro Gly Pro Pro  Arg Ser Arg Thr Thr  Pro Leu Gly 
    1010                 1015                 1020             


Gly Leu  Gly Pro Gly Glu Ala  Arg Asp Tyr Ser Pro  Ser Arg Asn 
    1025                 1030                 1035             


Pro Pro  Glu Val Glu Ala Arg  
    1040                 1045 


<210>  3611
<211>  277
<212>  PRT
<213>  homo sapiens

<400>  3611

Met Gly Leu Leu Glu Cys Cys Ala Arg Cys Leu Val Gly Ala Pro Phe 
1               5                   10                  15      


Ala Ser Leu Val Ala Thr Gly Leu Cys Phe Phe Gly Val Ala Leu Phe 
            20                  25                  30          


Cys Gly Cys Gly His Glu Ala Leu Thr Gly Thr Glu Lys Leu Ile Glu 
        35                  40                  45              


Thr Tyr Phe Ser Lys Asn Tyr Gln Asp Tyr Glu Tyr Leu Ile Asn Val 
    50                  55                  60                  


Ile His Ala Phe Gln Tyr Val Ile Tyr Gly Thr Ala Ser Phe Phe Phe 
65                  70                  75                  80  


Leu Tyr Gly Ala Leu Leu Leu Ala Glu Gly Phe Tyr Thr Thr Gly Ala 
                85                  90                  95      


Val Arg Gln Ile Phe Gly Asp Tyr Lys Thr Thr Ile Cys Gly Lys Gly 
            100                 105                 110         


Leu Ser Ala Thr Val Thr Gly Gly Gln Lys Gly Arg Gly Ser Arg Gly 
        115                 120                 125             


Gln His Gln Ala His Ser Leu Glu Arg Val Cys His Cys Leu Gly Lys 
    130                 135                 140                 


Trp Leu Gly His Pro Asp Lys Phe Val Gly Ile Thr Tyr Ala Leu Thr 
145                 150                 155                 160 


Val Val Trp Leu Leu Val Phe Ala Cys Ser Ala Val Pro Val Tyr Ile 
                165                 170                 175     


Tyr Phe Asn Thr Trp Thr Thr Cys Gln Ser Ile Ala Phe Pro Ser Lys 
            180                 185                 190         


Thr Ser Ala Ser Ile Gly Ser Leu Cys Ala Asp Ala Arg Met Tyr Gly 
        195                 200                 205             


Val Leu Pro Trp Asn Ala Phe Pro Gly Lys Val Cys Gly Ser Asn Leu 
    210                 215                 220                 


Leu Ser Ile Cys Lys Thr Ala Glu Phe Gln Met Thr Phe His Leu Phe 
225                 230                 235                 240 


Ile Ala Ala Phe Val Gly Ala Ala Ala Thr Leu Val Ser Leu Leu Thr 
                245                 250                 255     


Phe Met Ile Ala Ala Thr Tyr Asn Phe Ala Val Leu Lys Leu Met Gly 
            260                 265                 270         


Arg Gly Thr Lys Phe 
        275         


<210>  3612
<211>  2294
<212>  PRT
<213>  homo sapiens

<400>  3612

Met His Val Ser Leu Ala Glu Ala Leu Glu Val Arg Gly Gly Pro Leu 
1               5                   10                  15      


Gln Glu Glu Glu Ile Trp Ala Val Leu Asn Gln Ser Ala Glu Ser Leu 
            20                  25                  30          


Gln Glu Leu Phe Arg Lys Val Ser Leu Ala Asp Pro Ala Ala Leu Gly 
        35                  40                  45              


Phe Ile Ile Ser Pro Trp Ser Leu Leu Leu Leu Pro Ser Gly Ser Val 
    50                  55                  60                  


Ser Phe Thr Asp Glu Asn Ile Ser Asn Gln Asp Leu Arg Ala Phe Thr 
65                  70                  75                  80  


Ala Pro Glu Val Leu Gln Asn Gln Ser Leu Thr Ser Leu Ser Asp Val 
                85                  90                  95      


Glu Lys Ile His Ile Tyr Ser Leu Gly Met Thr Leu Tyr Trp Gly Ala 
            100                 105                 110         


Asp Tyr Glu Val Pro Gln Ser Gln Pro Ile Lys Leu Gly Asp His Leu 
        115                 120                 125             


Asn Ser Ile Leu Leu Gly Met Cys Glu Asp Val Ile Tyr Ala Arg Val 
    130                 135                 140                 


Ser Val Arg Thr Val Leu Asp Ala Cys Ser Ala His Ile Arg Asn Ser 
145                 150                 155                 160 


Asn Cys Ala Pro Ser Phe Ser Tyr Val Lys His Leu Val Lys Leu Val 
                165                 170                 175     


Leu Gly Asn Leu Ser Gly Thr Asp Gln Leu Ser Cys Asn Ser Glu Gln 
            180                 185                 190         


Lys Pro Asp Arg Ser Gln Ala Ile Arg Asp Arg Leu Arg Gly Lys Gly 
        195                 200                 205             


Leu Pro Thr Gly Arg Ser Ser Thr Ser Asp Val Leu Asp Ile Gln Lys 
    210                 215                 220                 


Pro Pro Leu Ser His Gln Thr Phe Leu Asn Lys Gly Leu Ser Lys Ser 
225                 230                 235                 240 


Met Gly Phe Leu Ser Ile Lys Asp Thr Gln Asp Glu Asn Tyr Phe Lys 
                245                 250                 255     


Asp Ile Leu Ser Asp Asn Ser Gly Arg Glu Asp Ser Glu Asn Thr Phe 
            260                 265                 270         


Ser Pro Tyr Gln Phe Lys Thr Ser Gly Pro Glu Lys Lys Pro Ile Pro 
        275                 280                 285             


Gly Ile Asp Val Leu Ser Lys Lys Lys Ile Trp Ala Ser Ser Met Asp 
    290                 295                 300                 


Leu Leu Cys Thr Ala Asp Arg Asp Phe Ser Ser Gly Glu Thr Ala Thr 
305                 310                 315                 320 


Tyr Arg Arg Cys His Pro Glu Ala Val Thr Val Arg Thr Ser Thr Thr 
                325                 330                 335     


Pro Arg Lys Lys Glu Ala Arg Tyr Ser Asp Gly Ser Ile Ala Leu Asp 
            340                 345                 350         


Ile Phe Gly Pro Gln Lys Met Asp Pro Ile Tyr His Thr Arg Glu Leu 
        355                 360                 365             


Pro Thr Ser Ser Ala Ile Ser Ser Ala Leu Asp Arg Ile Arg Glu Arg 
    370                 375                 380                 


Gln Lys Lys Leu Gln Val Leu Arg Glu Ala Met Asn Val Glu Glu Pro 
385                 390                 395                 400 


Val Arg Arg Tyr Lys Thr Tyr His Gly Asp Val Phe Ser Thr Ser Ser 
                405                 410                 415     


Glu Ser Pro Ser Ile Ile Ser Ser Glu Ser Asp Phe Arg Gln Val Arg 
            420                 425                 430         


Arg Ser Glu Ala Ser Lys Arg Phe Glu Ser Ser Ser Gly Leu Pro Gly 
        435                 440                 445             


Val Asp Glu Thr Leu Ser Gln Gly Gln Ser Gln Arg Pro Ser Arg Gln 
    450                 455                 460                 


Tyr Glu Thr Pro Phe Glu Gly Asn Leu Ile Asn Gln Glu Ile Met Leu 
465                 470                 475                 480 


Lys Arg Gln Glu Glu Glu Leu Met Gln Leu Gln Ala Lys Met Ala Leu 
                485                 490                 495     


Arg Gln Ser Arg Leu Ser Leu Tyr Pro Gly Asp Thr Ile Lys Ala Ser 
            500                 505                 510         


Met Leu Asp Ile Thr Arg Asp Pro Leu Arg Glu Ile Ala Leu Glu Thr 
        515                 520                 525             


Ala Met Thr Gln Arg Lys Leu Arg Asn Phe Phe Gly Pro Glu Phe Val 
    530                 535                 540                 


Lys Met Thr Ile Glu Pro Phe Ile Ser Leu Asp Leu Pro Arg Ser Ile 
545                 550                 555                 560 


Leu Thr Lys Lys Gly Lys Asn Glu Asp Asn Arg Arg Lys Val Asn Ile 
                565                 570                 575     


Met Leu Leu Asn Gly Gln Arg Leu Glu Leu Thr Cys Asp Thr Lys Thr 
            580                 585                 590         


Ile Cys Lys Asp Val Phe Asp Met Val Val Ala His Ile Gly Leu Val 
        595                 600                 605             


Glu His His Leu Phe Ala Leu Ala Thr Leu Lys Asp Asn Glu Tyr Phe 
    610                 615                 620                 


Phe Val Asp Pro Asp Leu Lys Leu Thr Lys Val Ala Pro Glu Gly Trp 
625                 630                 635                 640 


Lys Glu Glu Pro Lys Lys Lys Thr Lys Ala Thr Val Asn Phe Thr Leu 
                645                 650                 655     


Phe Phe Arg Ile Lys Phe Phe Met Asp Asp Val Ser Leu Ile Gln His 
            660                 665                 670         


Thr Leu Thr Cys His Gln Tyr Tyr Leu Gln Leu Arg Lys Asp Ile Leu 
        675                 680                 685             


Glu Glu Arg Met His Cys Asp Asp Glu Thr Ser Leu Leu Leu Ala Ser 
    690                 695                 700                 


Leu Ala Leu Gln Ala Glu Tyr Gly Asp Tyr Gln Pro Glu Val His Gly 
705                 710                 715                 720 


Val Ser Tyr Phe Arg Met Glu His Tyr Leu Pro Ala Arg Val Met Glu 
                725                 730                 735     


Lys Leu Asp Leu Ser Tyr Ile Lys Glu Glu Leu Pro Lys Leu His Asn 
            740                 745                 750         


Thr Tyr Val Gly Ala Ser Glu Lys Glu Thr Glu Leu Glu Phe Leu Lys 
        755                 760                 765             


Val Cys Gln Arg Leu Thr Glu Tyr Gly Val His Phe His Arg Val His 
    770                 775                 780                 


Pro Glu Lys Lys Ser Gln Thr Gly Ile Leu Leu Gly Val Cys Ser Lys 
785                 790                 795                 800 


Gly Val Leu Val Phe Glu Val His Asn Gly Val Arg Thr Leu Val Leu 
                805                 810                 815     


Arg Phe Pro Trp Arg Glu Thr Lys Lys Ile Ser Phe Ser Lys Lys Lys 
            820                 825                 830         


Ile Thr Leu Gln Asn Thr Ser Asp Gly Ile Lys His Gly Phe Gln Thr 
        835                 840                 845             


Asp Asn Ser Lys Ile Cys Gln Tyr Leu Leu His Leu Cys Ser Tyr Gln 
    850                 855                 860                 


His Lys Phe Gln Leu Gln Met Arg Ala Arg Gln Ser Asn Gln Asp Ala 
865                 870                 875                 880 


Gln Asp Ile Asp Val Leu His Lys Arg Trp Ser Ile Val Ser Ser Pro 
                885                 890                 895     


Glu Arg Glu Ile Thr Leu Val Asn Leu Lys Lys Asp Ala Lys Tyr Gly 
            900                 905                 910         


Leu Gly Phe Gln Ile Ile Gly Gly Glu Lys Met Gly Arg Leu Asp Leu 
        915                 920                 925             


Gly Ile Phe Ile Ser Ser Val Ala Pro Gly Gly Pro Ala Asp Leu Asp 
    930                 935                 940                 


Gly Cys Leu Lys Pro Gly Asp Arg Leu Ile Ser Val Asn Ser Val Ser 
945                 950                 955                 960 


Leu Glu Gly Val Ser His His Ala Ala Ile Glu Ile Leu Gln Asn Ala 
                965                 970                 975     


Pro Glu Asp Val Thr Leu Val Ile Ser Gln Pro Lys Glu Lys Ile Ser 
            980                 985                 990         


Lys Val Pro Ser Thr Pro Val His  Leu Thr Asn Glu Met  Lys Asn Tyr 
        995                 1000                 1005             


Met Lys  Lys Ser Ser Tyr Met  Gln Asp Ser Ala Ile  Asp Ser Ser 
    1010                 1015                 1020             


Ser Lys  Asp His His Trp Ser  Arg Gly Thr Leu Arg  His Ile Ser 
    1025                 1030                 1035             


Glu Asn  Ser Phe Gly Pro Ser  Gly Gly Leu Arg Glu  Gly Ser Leu 
    1040                 1045                 1050             


Ser Ser  Gln Asp Ser Arg Thr  Glu Ser Ala Ser Leu  Ser Gln Ser 
    1055                 1060                 1065             


Gln Val  Asn Gly Phe Phe Ala  Ser His Leu Gly Asp  Gln Thr Trp 
    1070                 1075                 1080             


Gln Glu  Ser Gln His Gly Ser  Pro Ser Pro Ser Val  Ile Ser Lys 
    1085                 1090                 1095             


Ala Thr  Glu Lys Glu Thr Phe  Thr Asp Ser Asn Gln  Ser Lys Thr 
    1100                 1105                 1110             


Lys Lys  Pro Gly Ile Ser Asp  Val Thr Asp Tyr Ser  Asp Arg Gly 
    1115                 1120                 1125             


Asp Ser  Asp Met Asp Glu Ala  Thr Tyr Ser Ser Ser  Gln Asp His 
    1130                 1135                 1140             


Gln Thr  Pro Lys Gln Glu Ser  Ser Ser Ser Val Asn  Thr Ser Asn 
    1145                 1150                 1155             


Lys Met  Asn Phe Lys Thr Phe  Ser Ser Ser Pro Pro  Lys Pro Gly 
    1160                 1165                 1170             


Asp Ile  Phe Glu Val Glu Leu  Ala Lys Asn Asp Asn  Ser Leu Gly 
    1175                 1180                 1185             


Ile Ser  Val Thr Gly Gly Val  Asn Thr Ser Val Arg  His Gly Gly 
    1190                 1195                 1200             


Ile Tyr  Val Lys Ala Val Ile  Pro Gln Gly Ala Ala  Glu Ser Asp 
    1205                 1210                 1215             


Gly Arg  Ile His Lys Gly Asp  Arg Val Leu Ala Val  Asn Gly Val 
    1220                 1225                 1230             


Ser Leu  Glu Gly Ala Thr His  Lys Gln Ala Val Glu  Thr Leu Arg 
    1235                 1240                 1245             


Asn Thr  Gly Gln Val Val His  Leu Leu Leu Glu Lys  Gly Gln Ser 
    1250                 1255                 1260             


Pro Thr  Ser Lys Glu His Val  Pro Val Thr Pro Gln  Cys Thr Leu 
    1265                 1270                 1275             


Ser Asp  Gln Asn Ala Gln Gly  Gln Gly Pro Glu Lys  Val Lys Lys 
    1280                 1285                 1290             


Thr Thr  Gln Val Lys Asp Tyr  Ser Phe Val Thr Glu  Glu Asn Thr 
    1295                 1300                 1305             


Phe Glu  Val Lys Leu Phe Lys  Asn Ser Ser Gly Leu  Gly Phe Ser 
    1310                 1315                 1320             


Phe Ser  Arg Glu Asp Asn Leu  Ile Pro Glu Gln Ile  Asn Ala Ser 
    1325                 1330                 1335             


Ile Val  Arg Val Lys Lys Leu  Phe Pro Gly Gln Pro  Ala Ala Glu 
    1340                 1345                 1350             


Ser Gly  Lys Ile Asp Val Gly  Asp Val Ile Leu Lys  Val Asn Gly 
    1355                 1360                 1365             


Ala Ser  Leu Lys Gly Leu Ser  Gln Gln Glu Val Ile  Ser Ala Leu 
    1370                 1375                 1380             


Arg Gly  Thr Ala Pro Glu Val  Phe Leu Leu Leu Cys  Arg Pro Pro 
    1385                 1390                 1395             


Pro Gly  Val Leu Pro Glu Ile  Asp Thr Ala Leu Leu  Thr Pro Leu 
    1400                 1405                 1410             


Gln Ser  Pro Ala Gln Val Leu  Pro Asn Ser Ser Lys  Asp Ser Ser 
    1415                 1420                 1425             


Gln Pro  Ser Cys Val Glu Gln  Ser Thr Ser Ser Asp  Glu Asn Glu 
    1430                 1435                 1440             


Met Ser  Asp Lys Ser Lys Lys  Gln Cys Lys Ser Pro  Ser Arg Arg 
    1445                 1450                 1455             


Asp Ser  Tyr Ser Asp Ser Ser  Gly Ser Gly Glu Asp  Asp Leu Val 
    1460                 1465                 1470             


Thr Ala  Pro Ala Asn Ile Ser  Asn Ser Thr Trp Ser  Ser Ala Leu 
    1475                 1480                 1485             


His Gln  Thr Leu Ser Asn Met  Val Ser Gln Ala Gln  Ser His His 
    1490                 1495                 1500             


Glu Ala  Pro Lys Ser Gln Glu  Asp Thr Ile Cys Thr  Met Phe Tyr 
    1505                 1510                 1515             


Tyr Pro  Gln Lys Ile Pro Asn  Lys Pro Glu Phe Glu  Asp Ser Asn 
    1520                 1525                 1530             


Pro Ser  Pro Leu Pro Pro Asp  Met Ala Pro Gly Gln  Ser Tyr Gln 
    1535                 1540                 1545             


Pro Gln  Ser Glu Ser Ala Ser  Ser Ser Ser Met Asp  Lys Tyr His 
    1550                 1555                 1560             


Ile His  His Ile Ser Glu Pro  Thr Arg Gln Glu Asn  Trp Thr Pro 
    1565                 1570                 1575             


Leu Lys  Asn Asp Leu Glu Asn  His Leu Glu Asp Phe  Glu Leu Glu 
    1580                 1585                 1590             


Val Glu  Leu Leu Ile Thr Leu  Ile Lys Ser Glu Lys  Gly Ser Leu 
    1595                 1600                 1605             


Gly Phe  Thr Val Thr Lys Gly  Asn Gln Arg Ile Gly  Cys Tyr Val 
    1610                 1615                 1620             


His Asp  Val Ile Gln Asp Pro  Ala Lys Ser Asp Gly  Arg Leu Lys 
    1625                 1630                 1635             


Pro Gly  Asp Arg Leu Ile Lys  Val Asn Asp Thr Asp  Val Thr Asn 
    1640                 1645                 1650             


Met Thr  His Thr Asp Ala Val  Asn Leu Leu Arg Ala  Ala Ser Lys 
    1655                 1660                 1665             


Thr Val  Arg Leu Val Ile Gly  Arg Val Leu Glu Leu  Pro Arg Ile 
    1670                 1675                 1680             


Pro Met  Leu Pro His Leu Leu  Pro Asp Ile Thr Leu  Thr Cys Asn 
    1685                 1690                 1695             


Lys Glu  Glu Leu Gly Phe Ser  Leu Cys Gly Gly His  Asp Ser Leu 
    1700                 1705                 1710             


Tyr Gln  Val Val Tyr Ile Ser  Asp Ile Asn Pro Arg  Ser Val Ala 
    1715                 1720                 1725             


Ala Ile  Glu Gly Asn Leu Gln  Leu Leu Asp Val Ile  His Tyr Val 
    1730                 1735                 1740             


Asn Gly  Val Ser Thr Gln Gly  Met Thr Leu Glu Glu  Val Asn Arg 
    1745                 1750                 1755             


Ala Leu  Asp Met Ser Leu Pro  Ser Leu Val Leu Lys  Ala Thr Arg 
    1760                 1765                 1770             


Asn Asp  Leu Pro Val Val Pro  Ser Ser Lys Arg Ser  Ala Val Ser 
    1775                 1780                 1785             


Ala Pro  Lys Ser Thr Lys Gly  Asn Gly Ser Tyr Ser  Val Gly Ser 
    1790                 1795                 1800             


Cys Ser  Gln Pro Ala Leu Thr  Pro Asn Asp Ser Phe  Ser Thr Val 
    1805                 1810                 1815             


Ala Gly  Glu Glu Ile Asn Glu  Ile Ser Tyr Pro Lys  Gly Lys Cys 
    1820                 1825                 1830             


Ser Thr  Tyr Gln Ile Lys Gly  Ser Pro Asn Leu Thr  Leu Pro Lys 
    1835                 1840                 1845             


Glu Ser  Tyr Ile Gln Glu Asp  Asp Ile Tyr Asp Asp  Ser Gln Glu 
    1850                 1855                 1860             


Ala Glu  Val Ile Gln Ser Leu  Leu Asp Val Val Asp  Glu Glu Ala 
    1865                 1870                 1875             


Gln Asn  Leu Leu Asn Glu Asn  Asn Ala Ala Gly Tyr  Ser Cys Gly 
    1880                 1885                 1890             


Pro Gly  Thr Leu Lys Met Asn  Gly Lys Leu Ser Glu  Glu Arg Thr 
    1895                 1900                 1905             


Glu Asp  Thr Asp Cys Asp Gly  Ser Pro Leu Pro Glu  Tyr Phe Thr 
    1910                 1915                 1920             


Glu Ala  Thr Lys Met Asn Gly  Cys Glu Glu Tyr Cys  Glu Glu Lys 
    1925                 1930                 1935             


Val Lys  Ser Glu Ser Leu Ile  Gln Lys Pro Gln Glu  Lys Lys Thr 
    1940                 1945                 1950             


Asp Asp  Asp Glu Ile Thr Trp  Gly Asn Asp Glu Leu  Pro Ile Glu 
    1955                 1960                 1965             


Arg Thr  Asn His Glu Asp Ser  Asp Lys Asp His Ser  Phe Leu Thr 
    1970                 1975                 1980             


Asn Asp  Glu Leu Ala Val Leu  Pro Val Val Lys Val  Leu Pro Ser 
    1985                 1990                 1995             


Gly Lys  Tyr Thr Gly Ala Asn  Leu Lys Ser Val Ile  Arg Val Leu 
    2000                 2005                 2010             


Arg Gly  Leu Leu Asp Gln Gly  Ile Pro Ser Lys Glu  Leu Glu Asn 
    2015                 2020                 2025             


Leu Gln  Glu Leu Lys Pro Leu  Asp Gln Cys Leu Ile  Gly Gln Thr 
    2030                 2035                 2040             


Lys Glu  Asn Arg Arg Lys Asn  Arg Tyr Lys Asn Ile  Leu Pro Tyr 
    2045                 2050                 2055             


Asp Ala  Thr Arg Val Pro Leu  Gly Asp Glu Gly Gly  Tyr Ile Asn 
    2060                 2065                 2070             


Ala Ser  Phe Ile Lys Ile Pro  Val Gly Lys Glu Glu  Phe Val Tyr 
    2075                 2080                 2085             


Ile Ala  Cys Gln Gly Pro Leu  Pro Thr Thr Val Gly  Asp Phe Trp 
    2090                 2095                 2100             


Gln Met  Ile Trp Glu Gln Lys  Ser Thr Val Ile Ala  Met Met Thr 
    2105                 2110                 2115             


Gln Glu  Val Glu Gly Glu Lys  Ile Lys Cys Gln Arg  Tyr Trp Pro 
    2120                 2125                 2130             


Asn Ile  Leu Gly Lys Thr Thr  Met Val Ser Asn Arg  Leu Arg Leu 
    2135                 2140                 2145             


Ala Leu  Val Arg Met Gln Gln  Leu Lys Gly Phe Val  Val Arg Ala 
    2150                 2155                 2160             


Met Thr  Leu Glu Asp Ile Gln  Thr Arg Glu Val Arg  His Ile Ser 
    2165                 2170                 2175             


His Leu  Asn Phe Thr Ala Trp  Pro Asp His Asp Thr  Pro Ser Gln 
    2180                 2185                 2190             


Pro Asp  Asp Leu Leu Thr Phe  Ile Ser Tyr Met Arg  His Ile His 
    2195                 2200                 2205             


Arg Ser  Gly Pro Ile Ile Thr  His Cys Ser Ala Gly  Ile Gly Arg 
    2210                 2215                 2220             


Ser Gly  Thr Leu Ile Cys Ile  Asp Val Val Leu Gly  Leu Ile Ser 
    2225                 2230                 2235             


Gln Asp  Leu Asp Phe Asp Ile  Ser Asp Leu Val Arg  Cys Met Arg 
    2240                 2245                 2250             


Leu Gln  Arg His Gly Met Val  Gln Thr Glu Asp Gln  Tyr Ile Phe 
    2255                 2260                 2265             


Cys Tyr  Gln Val Ile Leu Tyr  Val Leu Thr Arg Leu  Gln Ala Glu 
    2270                 2275                 2280             


Glu Glu  Gln Lys Gln Gln Pro  Gln Leu Leu Lys 
    2285                 2290                 


<210>  3613
<211>  287
<212>  PRT
<213>  homo sapiens

<400>  3613

Met Ser Glu Glu Gln Phe Gly Gly Asp Gly Ala Ala Ala Ala Ala Thr 
1               5                   10                  15      


Ala Ala Val Gly Gly Ser Ala Gly Glu Gln Glu Gly Ala Met Val Ala 
            20                  25                  30          


Ala Thr Gln Gly Ala Ala Ala Ala Ala Gly Ser Gly Ala Gly Thr Gly 
        35                  40                  45              


Gly Gly Thr Ala Ser Gly Gly Thr Glu Gly Gly Ser Ala Glu Ser Glu 
    50                  55                  60                  


Gly Ala Lys Ile Asp Ala Ser Lys Asn Glu Glu Asp Glu Gly Lys Met 
65                  70                  75                  80  


Phe Ile Gly Gly Leu Ser Trp Asp Thr Thr Lys Lys Asp Leu Lys Asp 
                85                  90                  95      


Tyr Phe Ser Lys Phe Gly Glu Val Val Asp Cys Thr Leu Lys Leu Asp 
            100                 105                 110         


Pro Ile Thr Gly Arg Ser Arg Gly Phe Gly Phe Val Leu Phe Lys Glu 
        115                 120                 125             


Ser Glu Ser Val Asp Lys Val Met Asp Gln Lys Glu His Lys Leu Asn 
    130                 135                 140                 


Gly Lys Val Ile Asp Pro Lys Arg Ala Lys Ala Met Lys Thr Lys Glu 
145                 150                 155                 160 


Pro Val Lys Lys Ile Phe Val Gly Gly Leu Ser Pro Asp Thr Pro Glu 
                165                 170                 175     


Glu Lys Ile Arg Glu Tyr Phe Gly Gly Phe Gly Glu Val Glu Ser Ile 
            180                 185                 190         


Glu Leu Pro Met Asp Asn Lys Thr Asn Lys Arg Arg Gly Phe Cys Phe 
        195                 200                 205             


Ile Thr Phe Lys Glu Glu Glu Pro Val Lys Lys Ile Met Glu Lys Lys 
    210                 215                 220                 


Tyr His Asn Val Gly Leu Ser Lys Cys Glu Ile Lys Val Ala Met Ser 
225                 230                 235                 240 


Lys Glu Gln Tyr Gln Gln Gln Gln Gln Trp Gly Ser Arg Gly Gly Phe 
                245                 250                 255     


Ala Gly Arg Ala Arg Gly Arg Gly Gly Asp Gln Gln Ser Gly Tyr Gly 
            260                 265                 270         


Lys Val Ser Arg Arg Gly Gly His Gln Asn Ser Tyr Lys Pro Tyr 
        275                 280                 285         


<210>  3614
<211>  484
<212>  PRT
<213>  homo sapiens

<400>  3614

Met Phe Pro Asn Ser Ile Leu Gly Arg Pro Pro Phe Thr Pro Asn His 
1               5                   10                  15      


Gln Gln His Asn Asn Phe Phe Thr Leu Ser Pro Thr Val Tyr Ser His 
            20                  25                  30          


Gln Gln Leu Ile Asp Ala Gln Phe Asn Phe Gln Asn Ala Asp Leu Ser 
        35                  40                  45              


Arg Ala Val Ser Leu Gln Gln Leu Thr Tyr Gly Asn Val Ser Pro Ile 
    50                  55                  60                  


Gln Thr Ser Ala Ser Pro Leu Phe Arg Gly Arg Lys Arg Leu Ser Asp 
65                  70                  75                  80  


Glu Lys Asn Leu Pro Leu Asp Gly Lys Arg Gln Arg Phe His Ser Pro 
                85                  90                  95      


His Gln Glu Pro Thr Val Val Asn Gln Ile Val Pro Leu Ser Gly Glu 
            100                 105                 110         


Arg Arg Tyr Ser Met Pro Pro Leu Phe His Thr His Tyr Val Pro Asp 
        115                 120                 125             


Ile Val Arg Cys Val Pro Pro Phe Arg Glu Ile Ala Phe Leu Glu Pro 
    130                 135                 140                 


Arg Glu Ile Thr Leu Pro Glu Ala Lys Asp Lys Leu Ser Gln Gln Ile 
145                 150                 155                 160 


Leu Glu Leu Phe Glu Thr Cys Gln Gln Gln Ile Ser Asp Leu Lys Lys 
                165                 170                 175     


Lys Glu Leu Cys Arg Thr Gln Leu Gln Arg Glu Ile Gln Leu Leu Phe 
            180                 185                 190         


Pro Gln Ser Arg Leu Phe Leu Val Gly Ser Ser Leu Asn Gly Phe Gly 
        195                 200                 205             


Thr Arg Ser Ser Asp Gly Asp Leu Cys Leu Val Val Lys Glu Glu Pro 
    210                 215                 220                 


Cys Phe Phe Gln Val Asn Gln Lys Thr Glu Ala Arg His Ile Leu Thr 
225                 230                 235                 240 


Leu Val His Lys His Phe Cys Thr Arg Leu Ser Gly Tyr Ile Glu Arg 
                245                 250                 255     


Pro Gln Leu Ile Arg Ala Lys Val Pro Ile Val Lys Phe Arg Asp Lys 
            260                 265                 270         


Val Ser Cys Val Glu Phe Asp Leu Asn Val Asn Asn Ile Val Gly Ile 
        275                 280                 285             


Arg Asn Thr Phe Leu Leu Arg Thr Tyr Ala Tyr Leu Glu Asn Arg Val 
    290                 295                 300                 


Arg Pro Leu Val Leu Val Ile Lys Lys Trp Ala Ser His His Gln Ile 
305                 310                 315                 320 


Asn Asp Ala Ser Arg Gly Thr Leu Ser Ser Tyr Ser Leu Val Leu Met 
                325                 330                 335     


Val Leu His Tyr Leu Gln Thr Leu Pro Glu Pro Ile Leu Pro Ser Leu 
            340                 345                 350         


Gln Lys Ile Tyr Pro Glu Ser Phe Ser Pro Ala Ile Gln Leu His Leu 
        355                 360                 365             


Val His Gln Ala Pro Cys Asn Val Pro Pro Tyr Leu Ser Lys Asn Glu 
    370                 375                 380                 


Ser Asn Leu Gly Asp Leu Leu Leu Gly Phe Leu Lys Tyr Tyr Ala Thr 
385                 390                 395                 400 


Glu Phe Asp Trp Asn Ser Gln Met Ile Ser Val Arg Glu Ala Lys Ala 
                405                 410                 415     


Ile Pro Arg Pro Asp Gly Ile Glu Trp Arg Asn Lys Tyr Ile Cys Val 
            420                 425                 430         


Glu Glu Pro Phe Asp Gly Thr Asn Thr Ala Arg Ala Val His Glu Lys 
        435                 440                 445             


Gln Lys Phe Asp Met Ile Lys Asp Gln Phe Leu Lys Ser Trp His Arg 
    450                 455                 460                 


Leu Lys Asn Lys Arg Asp Leu Asn Ser Ile Leu Pro Val Arg Ala Ala 
465                 470                 475                 480 


Val Leu Lys Arg 
                


<210>  3615
<211>  417
<212>  PRT
<213>  homo sapiens

<400>  3615

Met Ala Leu Lys Val Leu Leu Glu Gln Glu Lys Thr Phe Phe Thr Leu 
1               5                   10                  15      


Leu Val Leu Leu Gly Tyr Leu Ser Cys Lys Val Thr Cys Glu Ser Gly 
            20                  25                  30          


Asp Cys Arg Gln Gln Glu Phe Arg Asp Arg Ser Gly Asn Cys Val Pro 
        35                  40                  45              


Cys Asn Gln Cys Gly Pro Gly Met Glu Leu Ser Lys Glu Cys Gly Phe 
    50                  55                  60                  


Gly Tyr Gly Glu Asp Ala Gln Cys Val Thr Cys Arg Leu His Arg Phe 
65                  70                  75                  80  


Lys Glu Asp Trp Gly Phe Gln Lys Cys Lys Pro Cys Leu Asp Cys Ala 
                85                  90                  95      


Val Val Asn Arg Phe Gln Lys Ala Asn Cys Ser Ala Thr Ser Asp Ala 
            100                 105                 110         


Ile Cys Gly Asp Cys Leu Pro Gly Phe Tyr Arg Lys Thr Lys Leu Val 
        115                 120                 125             


Gly Phe Gln Asp Met Glu Cys Val Pro Cys Gly Asp Pro Pro Pro Pro 
    130                 135                 140                 


Tyr Glu Pro His Cys Ala Ser Lys Val Asn Leu Val Lys Ile Ala Ser 
145                 150                 155                 160 


Thr Ala Ser Ser Pro Arg Asp Thr Ala Leu Ala Ala Val Ile Cys Ser 
                165                 170                 175     


Ala Leu Ala Thr Val Leu Leu Ala Leu Leu Ile Leu Cys Val Ile Tyr 
            180                 185                 190         


Cys Lys Arg Gln Phe Met Glu Lys Lys Pro Ser Trp Ser Leu Arg Ser 
        195                 200                 205             


Gln Asp Ile Gln Tyr Asn Gly Ser Glu Leu Ser Cys Phe Asp Arg Pro 
    210                 215                 220                 


Gln Leu His Glu Tyr Ala His Arg Ala Cys Cys Gln Cys Arg Arg Asp 
225                 230                 235                 240 


Ser Val Gln Thr Cys Gly Pro Val Arg Leu Leu Pro Ser Met Cys Cys 
                245                 250                 255     


Glu Glu Ala Cys Ser Pro Asn Pro Ala Thr Leu Gly Cys Gly Val His 
            260                 265                 270         


Ser Ala Ala Ser Leu Gln Ala Arg Asn Ala Gly Pro Ala Gly Glu Met 
        275                 280                 285             


Val Pro Thr Phe Phe Gly Ser Leu Thr Gln Ser Ile Cys Gly Glu Phe 
    290                 295                 300                 


Ser Asp Ala Trp Pro Leu Met Gln Asn Pro Met Gly Gly Asp Asn Ile 
305                 310                 315                 320 


Ser Phe Cys Asp Ser Tyr Pro Glu Leu Thr Gly Glu Asp Ile His Ser 
                325                 330                 335     


Leu Asn Pro Glu Leu Glu Ser Ser Thr Ser Leu Asp Ser Asn Ser Ser 
            340                 345                 350         


Gln Asp Leu Val Gly Gly Ala Val Pro Val Gln Ser His Ser Glu Asn 
        355                 360                 365             


Phe Thr Ala Ala Thr Asp Leu Ser Arg Tyr Asn Asn Thr Leu Val Glu 
    370                 375                 380                 


Ser Ala Ser Thr Gln Asp Ala Leu Thr Met Arg Ser Gln Leu Asp Gln 
385                 390                 395                 400 


Glu Ser Gly Ala Val Ile His Pro Ala Thr Gln Thr Ser Leu Gln Glu 
                405                 410                 415     


Ala 
    


<210>  3616
<211>  655
<212>  PRT
<213>  homo sapiens

<400>  3616

Met Gly Thr Ser Pro Ser Ser Ser Thr Ala Leu Ala Ser Cys Ser Arg 
1               5                   10                  15      


Ile Ala Arg Arg Ala Thr Ala Thr Met Ile Ala Gly Ser Leu Leu Leu 
            20                  25                  30          


Leu Gly Phe Leu Ser Thr Thr Thr Ala Gln Pro Glu Gln Lys Ala Ser 
        35                  40                  45              


Asn Leu Ile Gly Thr Tyr Arg His Val Asp Arg Ala Thr Gly Gln Val 
    50                  55                  60                  


Leu Thr Cys Asp Lys Cys Pro Ala Gly Thr Tyr Val Ser Glu His Cys 
65                  70                  75                  80  


Thr Asn Thr Ser Leu Arg Val Cys Ser Ser Cys Pro Val Gly Thr Phe 
                85                  90                  95      


Thr Arg His Glu Asn Gly Ile Glu Lys Cys His Asp Cys Ser Gln Pro 
            100                 105                 110         


Cys Pro Trp Pro Met Ile Glu Lys Leu Pro Cys Ala Ala Leu Thr Asp 
        115                 120                 125             


Arg Glu Cys Thr Cys Pro Pro Gly Met Phe Gln Ser Asn Ala Thr Cys 
    130                 135                 140                 


Ala Pro His Thr Val Cys Pro Val Gly Trp Gly Val Arg Lys Lys Gly 
145                 150                 155                 160 


Thr Glu Thr Glu Asp Val Arg Cys Lys Gln Cys Ala Arg Gly Thr Phe 
                165                 170                 175     


Ser Asp Val Pro Ser Ser Val Met Lys Cys Lys Ala Tyr Thr Asp Cys 
            180                 185                 190         


Leu Ser Gln Asn Leu Val Val Ile Lys Pro Gly Thr Lys Glu Thr Asp 
        195                 200                 205             


Asn Val Cys Gly Thr Leu Pro Ser Phe Ser Ser Ser Thr Ser Pro Ser 
    210                 215                 220                 


Pro Gly Thr Ala Ile Phe Pro Arg Pro Glu His Met Glu Thr His Glu 
225                 230                 235                 240 


Val Pro Ser Ser Thr Tyr Val Pro Lys Gly Met Asn Ser Thr Glu Ser 
                245                 250                 255     


Asn Ser Ser Ala Ser Val Arg Pro Lys Val Leu Ser Ser Ile Gln Glu 
            260                 265                 270         


Gly Thr Val Pro Asp Asn Thr Ser Ser Ala Arg Gly Lys Glu Asp Val 
        275                 280                 285             


Asn Lys Thr Leu Pro Asn Leu Gln Val Val Asn His Gln Gln Gly Pro 
    290                 295                 300                 


His His Arg His Ile Leu Lys Leu Leu Pro Ser Met Glu Ala Thr Gly 
305                 310                 315                 320 


Gly Glu Lys Ser Ser Thr Pro Ile Lys Gly Pro Lys Arg Gly His Pro 
                325                 330                 335     


Arg Gln Asn Leu His Lys His Phe Asp Ile Asn Glu His Leu Pro Trp 
            340                 345                 350         


Met Ile Val Leu Phe Leu Leu Leu Val Leu Val Val Ile Val Val Cys 
        355                 360                 365             


Ser Ile Arg Lys Ser Ser Arg Thr Leu Lys Lys Gly Pro Arg Gln Asp 
    370                 375                 380                 


Pro Ser Ala Ile Val Glu Lys Ala Gly Leu Lys Lys Ser Met Thr Pro 
385                 390                 395                 400 


Thr Gln Asn Arg Glu Lys Trp Ile Tyr Tyr Cys Asn Gly His Gly Ile 
                405                 410                 415     


Asp Ile Leu Lys Leu Val Ala Ala Gln Val Gly Ser Gln Trp Lys Asp 
            420                 425                 430         


Ile Tyr Gln Phe Leu Cys Asn Ala Ser Glu Arg Glu Val Ala Ala Phe 
        435                 440                 445             


Ser Asn Gly Tyr Thr Ala Asp His Glu Arg Ala Tyr Ala Ala Leu Gln 
    450                 455                 460                 


His Trp Thr Ile Arg Gly Pro Glu Ala Ser Leu Ala Gln Leu Ile Ser 
465                 470                 475                 480 


Ala Leu Arg Gln His Arg Arg Asn Asp Val Val Glu Lys Ile Arg Gly 
                485                 490                 495     


Leu Met Glu Asp Thr Thr Gln Leu Glu Thr Asp Lys Leu Ala Leu Pro 
            500                 505                 510         


Met Ser Pro Ser Pro Leu Ser Pro Ser Pro Ile Pro Ser Pro Asn Ala 
        515                 520                 525             


Lys Leu Glu Asn Ser Ala Leu Leu Thr Val Glu Pro Ser Pro Gln Asp 
    530                 535                 540                 


Lys Asn Lys Gly Phe Phe Val Asp Glu Ser Glu Pro Leu Leu Arg Cys 
545                 550                 555                 560 


Asp Ser Thr Ser Ser Gly Ser Ser Ala Leu Ser Arg Asn Gly Ser Phe 
                565                 570                 575     


Ile Thr Lys Glu Lys Lys Asp Thr Val Leu Arg Gln Val Arg Leu Asp 
            580                 585                 590         


Pro Cys Asp Leu Gln Pro Ile Phe Asp Asp Met Leu His Phe Leu Asn 
        595                 600                 605             


Pro Glu Glu Leu Arg Val Ile Glu Glu Ile Pro Gln Ala Glu Asp Lys 
    610                 615                 620                 


Leu Asp Arg Leu Phe Glu Ile Ile Gly Val Lys Ser Gln Glu Ala Ser 
625                 630                 635                 640 


Gln Thr Leu Leu Asp Ser Val Tyr Ser His Leu Pro Asp Leu Leu 
                645                 650                 655 


<210>  3617
<211>  278
<212>  PRT
<213>  homo sapiens

<400>  3617

Met Ser Asp Thr Glu Glu Gln Glu Tyr Glu Glu Glu Gln Pro Glu Glu 
1               5                   10                  15      


Glu Ala Ala Glu Glu Glu Glu Glu Ala Pro Glu Glu Pro Glu Pro Val 
            20                  25                  30          


Ala Glu Pro Glu Glu Glu Arg Pro Lys Pro Ser Arg Pro Val Val Pro 
        35                  40                  45              


Pro Leu Ile Pro Pro Lys Ile Pro Glu Gly Glu Arg Val Asp Phe Asp 
    50                  55                  60                  


Asp Ile His Arg Lys Arg Met Glu Lys Asp Leu Leu Glu Leu Gln Thr 
65                  70                  75                  80  


Leu Ile Asp Val His Phe Glu Gln Arg Lys Lys Glu Glu Glu Glu Leu 
                85                  90                  95      


Val Ala Leu Lys Glu Arg Ile Glu Arg Arg Arg Ser Glu Arg Ala Glu 
            100                 105                 110         


Gln Gln Arg Phe Arg Thr Glu Lys Glu Arg Glu Arg Gln Ala Lys Leu 
        115                 120                 125             


Ala Glu Glu Lys Met Arg Lys Glu Glu Glu Glu Ala Lys Lys Arg Ala 
    130                 135                 140                 


Glu Asp Asp Ala Lys Lys Lys Lys Val Leu Ser Asn Met Gly Ala His 
145                 150                 155                 160 


Phe Gly Gly Tyr Leu Val Lys Ala Glu Gln Lys Arg Gly Lys Arg Gln 
                165                 170                 175     


Thr Gly Arg Glu Met Lys Val Arg Ile Leu Ser Glu Arg Lys Lys Pro 
            180                 185                 190         


Leu Asp Ile Asp Tyr Met Gly Glu Glu Gln Leu Arg Ala Arg Ser Ala 
        195                 200                 205             


Trp Leu Pro Pro Ser Gln Pro Ser Cys Pro Ala Arg Glu Lys Ala Gln 
    210                 215                 220                 


Glu Leu Ser Asp Trp Ile His Gln Leu Glu Ser Glu Lys Phe Asp Leu 
225                 230                 235                 240 


Met Ala Lys Leu Lys Gln Gln Lys Tyr Glu Ile Asn Val Leu Tyr Asn 
                245                 250                 255     


Arg Ile Ser His Ala Gln Lys Phe Arg Lys Gly Ala Gly Lys Gly Arg 
            260                 265                 270         


Val Gly Gly Arg Trp Lys 
        275             


<210>  3618
<211>  262
<212>  PRT
<213>  homo sapiens

<400>  3618

Met Ser Asp Thr Glu Glu Gln Glu Tyr Glu Glu Glu Gln Pro Glu Glu 
1               5                   10                  15      


Glu Ala Ala Glu Glu Glu Glu Glu Ala Pro Glu Glu Pro Glu Pro Val 
            20                  25                  30          


Ala Glu Pro Glu Glu Glu Arg Pro Lys Pro Ser Arg Pro Val Val Pro 
        35                  40                  45              


Pro Leu Ile Pro Pro Lys Ile Pro Glu Gly Glu Arg Val Asp Phe Asp 
    50                  55                  60                  


Asp Ile His Arg Lys Arg Met Glu Lys Asp Leu Leu Glu Leu Gln Thr 
65                  70                  75                  80  


Leu Ile Asp Val His Phe Glu Gln Arg Lys Lys Glu Glu Glu Glu Leu 
                85                  90                  95      


Val Ala Leu Lys Glu Arg Ile Glu Arg Arg Arg Ser Glu Arg Ala Glu 
            100                 105                 110         


Gln Gln Arg Phe Arg Thr Glu Lys Glu Arg Glu Arg Gln Ala Lys Leu 
        115                 120                 125             


Ala Glu Glu Lys Met Arg Lys Glu Glu Glu Glu Ala Lys Lys Arg Ala 
    130                 135                 140                 


Glu Asp Asp Ala Lys Lys Lys Lys Val Leu Ser Asn Met Gly Ala His 
145                 150                 155                 160 


Phe Gly Gly Tyr Leu Val Lys Ala Glu Gln Lys Arg Gly Lys Arg Gln 
                165                 170                 175     


Thr Gly Arg Glu Met Lys Val Arg Ile Leu Ser Glu Arg Lys Lys Pro 
            180                 185                 190         


Leu Asp Ile Asp Tyr Met Gly Glu Glu Gln Leu Arg Glu Lys Ala Gln 
        195                 200                 205             


Glu Leu Ser Asp Trp Ile His Gln Leu Glu Ser Glu Lys Phe Asp Leu 
    210                 215                 220                 


Met Ala Lys Leu Lys Gln Gln Lys Tyr Glu Ile Asn Val Leu Tyr Asn 
225                 230                 235                 240 


Arg Ile Ser His Ala Gln Lys Phe Arg Lys Gly Ala Gly Lys Gly Arg 
                245                 250                 255     


Val Gly Gly Arg Trp Lys 
            260         


<210>  3619
<211>  251
<212>  PRT
<213>  homo sapiens

<400>  3619

Met Ser Asp Thr Glu Glu Gln Glu Tyr Glu Glu Glu Gln Pro Glu Glu 
1               5                   10                  15      


Glu Ala Ala Glu Glu Glu Glu Glu Glu Glu Glu Arg Pro Lys Pro Ser 
            20                  25                  30          


Arg Pro Val Val Pro Pro Leu Ile Pro Pro Lys Ile Pro Glu Gly Glu 
        35                  40                  45              


Arg Val Asp Phe Asp Asp Ile His Arg Lys Arg Met Glu Lys Asp Leu 
    50                  55                  60                  


Leu Glu Leu Gln Thr Leu Ile Asp Val His Phe Glu Gln Arg Lys Lys 
65                  70                  75                  80  


Glu Glu Glu Glu Leu Val Ala Leu Lys Glu Arg Ile Glu Arg Arg Arg 
                85                  90                  95      


Ser Glu Arg Ala Glu Gln Gln Arg Phe Arg Thr Glu Lys Glu Arg Glu 
            100                 105                 110         


Arg Gln Ala Lys Leu Ala Glu Glu Lys Met Arg Lys Glu Glu Glu Glu 
        115                 120                 125             


Ala Lys Lys Arg Ala Glu Asp Asp Ala Lys Lys Lys Lys Val Leu Ser 
    130                 135                 140                 


Asn Met Gly Ala His Phe Gly Gly Tyr Leu Val Lys Ala Glu Gln Lys 
145                 150                 155                 160 


Arg Gly Lys Arg Gln Thr Gly Arg Glu Met Lys Val Arg Ile Leu Ser 
                165                 170                 175     


Glu Arg Lys Lys Pro Leu Asp Ile Asp Tyr Met Gly Glu Glu Gln Leu 
            180                 185                 190         


Arg Glu Lys Ala Gln Glu Leu Ser Asp Trp Ile His Gln Leu Glu Ser 
        195                 200                 205             


Glu Lys Phe Asp Leu Met Ala Lys Leu Lys Gln Gln Lys Tyr Glu Ile 
    210                 215                 220                 


Asn Val Leu Tyr Asn Arg Ile Ser His Ala Gln Lys Phe Arg Lys Gly 
225                 230                 235                 240 


Ala Gly Lys Gly Arg Val Gly Gly Arg Trp Lys 
                245                 250     


<210>  3620
<211>  479
<212>  PRT
<213>  homo sapiens

<400>  3620

Met Ser Ser Pro Gly Ile Asp Gly Asp Pro Lys Pro Pro Cys Leu Pro 
1               5                   10                  15      


Arg Asn Gly Leu Val Lys Leu Pro Gly Gln Pro Asn Gly Leu Gly Ala 
            20                  25                  30          


Ala Ser Ile Thr Lys Gly Thr Pro Ala Thr Lys Asn Arg Pro Cys Gln 
        35                  40                  45              


Pro Pro Pro Pro Pro Thr Leu Pro Pro Pro Ser Leu Ala Ala Pro Leu 
    50                  55                  60                  


Ser Arg Ala Ala Leu Ala Gly Gly Pro Cys Thr Pro Ala Gly Gly Pro 
65                  70                  75                  80  


Ala Ser Ala Leu Ala Pro Gly His Pro Ala Glu Arg Pro Pro Leu Ala 
                85                  90                  95      


Thr Asp Glu Lys Ile Leu Asn Gly Leu Phe Trp Tyr Phe Ser Ala Cys 
            100                 105                 110         


Glu Lys Cys Val Leu Ala Gln Val Cys Lys Ala Trp Arg Arg Val Leu 
        115                 120                 125             


Tyr Gln Pro Lys Phe Trp Ala Gly Leu Thr Pro Val Leu His Ala Lys 
    130                 135                 140                 


Glu Leu Tyr Asn Val Leu Pro Gly Gly Glu Lys Glu Phe Val Asn Leu 
145                 150                 155                 160 


Gln Gly Phe Ala Ala Arg Gly Phe Glu Gly Phe Cys Leu Val Gly Val 
                165                 170                 175     


Ser Asp Leu Asp Ile Cys Glu Phe Ile Asp Asn Tyr Ala Leu Ser Lys 
            180                 185                 190         


Lys Gly Val Lys Ala Met Ser Leu Lys Arg Ser Thr Ile Thr Asp Ala 
        195                 200                 205             


Gly Leu Glu Val Met Leu Glu Gln Met Gln Gly Val Val Arg Leu Glu 
    210                 215                 220                 


Leu Ser Gly Cys Asn Asp Phe Thr Glu Ala Gly Leu Trp Ser Ser Leu 
225                 230                 235                 240 


Ser Ala Arg Ile Thr Ser Leu Ser Val Ser Asp Cys Ile Asn Val Ala 
                245                 250                 255     


Asp Asp Ala Ile Ala Ala Ile Ser Gln Leu Leu Pro Asn Leu Ala Glu 
            260                 265                 270         


Leu Ser Leu Gln Ala Tyr His Val Thr Asp Thr Ala Leu Ala Tyr Phe 
        275                 280                 285             


Thr Ala Arg Gln Gly His Ser Thr His Thr Leu Arg Leu Leu Ser Cys 
    290                 295                 300                 


Trp Glu Ile Thr Asn His Gly Val Val Asn Val Val His Ser Leu Pro 
305                 310                 315                 320 


Asn Leu Thr Ala Leu Ser Leu Ser Gly Cys Ser Lys Val Thr Asp Asp 
                325                 330                 335     


Gly Val Glu Leu Val Ala Glu Asn Leu Arg Lys Leu Arg Ser Leu Asp 
            340                 345                 350         


Leu Ser Trp Cys Pro Arg Ile Thr Asp Met Ala Leu Glu Tyr Val Ala 
        355                 360                 365             


Cys Asp Leu His Arg Leu Glu Glu Leu Val Leu Asp Arg Cys Val Arg 
    370                 375                 380                 


Ile Thr Asp Thr Gly Leu Ser Tyr Leu Ser Thr Met Ser Ser Leu Arg 
385                 390                 395                 400 


Ser Leu Tyr Leu Arg Trp Cys Cys Gln Val Gln Asp Phe Gly Leu Lys 
                405                 410                 415     


His Leu Leu Ala Leu Gly Ser Leu Arg Leu Leu Ser Leu Ala Gly Cys 
            420                 425                 430         


Pro Leu Leu Thr Thr Thr Gly Leu Ser Gly Leu Val Gln Leu Gln Glu 
        435                 440                 445             


Leu Glu Glu Leu Glu Leu Thr Asn Cys Pro Gly Ala Thr Pro Glu Leu 
    450                 455                 460                 


Phe Lys Tyr Phe Ser Gln His Leu Pro Arg Cys Leu Val Ile Glu 
465                 470                 475                 


<210>  3621
<211>  959
<212>  PRT
<213>  homo sapiens

<400>  3621

Met Ala Leu Leu Gly Lys Arg Cys Asp Val Pro Thr Asn Gly Cys Gly 
1               5                   10                  15      


Pro Asp Arg Trp Asn Ser Ala Phe Thr Arg Lys Asp Glu Ile Ile Thr 
            20                  25                  30          


Ser Leu Val Ser Ala Leu Asp Ser Met Cys Ser Ala Leu Ser Lys Leu 
        35                  40                  45              


Asn Ala Glu Val Ala Cys Val Ala Val His Asp Glu Ser Ala Phe Val 
    50                  55                  60                  


Val Gly Thr Glu Lys Gly Arg Met Phe Leu Asn Ala Arg Lys Glu Leu 
65                  70                  75                  80  


Gln Ser Asp Phe Leu Arg Phe Cys Arg Gly Pro Pro Trp Lys Asp Pro 
                85                  90                  95      


Glu Ala Glu His Pro Lys Lys Val Gln Arg Gly Glu Gly Gly Gly Arg 
            100                 105                 110         


Ser Leu Pro Arg Ser Ser Leu Glu His Gly Ser Asp Val Tyr Leu Leu 
        115                 120                 125             


Arg Lys Met Val Glu Glu Val Phe Asp Val Leu Tyr Ser Glu Ala Leu 
    130                 135                 140                 


Gly Arg Ala Ser Val Val Pro Leu Pro Tyr Glu Arg Leu Leu Arg Glu 
145                 150                 155                 160 


Pro Gly Leu Leu Ala Val Gln Gly Leu Pro Glu Gly Leu Ala Phe Arg 
                165                 170                 175     


Arg Pro Ala Glu Tyr Asp Pro Lys Ala Leu Met Ala Ile Leu Glu His 
            180                 185                 190         


Ser His Arg Ile Arg Phe Lys Leu Lys Arg Pro Leu Glu Asp Gly Gly 
        195                 200                 205             


Arg Asp Ser Lys Ala Leu Val Glu Leu Asn Gly Val Ser Leu Ile Pro 
    210                 215                 220                 


Lys Gly Ser Arg Asp Cys Gly Leu His Gly Gln Ala Pro Lys Val Pro 
225                 230                 235                 240 


Pro Gln Asp Leu Pro Pro Thr Ala Thr Ser Ser Ser Met Ala Ser Phe 
                245                 250                 255     


Leu Tyr Ser Thr Ala Leu Pro Asn His Ala Ile Arg Glu Leu Lys Gln 
            260                 265                 270         


Glu Ala Pro Ser Cys Pro Leu Ala Pro Ser Asp Leu Gly Leu Ser Arg 
        275                 280                 285             


Pro Met Pro Glu Pro Lys Ala Thr Gly Ala Gln Asp Phe Ser Asp Cys 
    290                 295                 300                 


Cys Gly Gln Lys Pro Thr Gly Pro Gly Gly Pro Leu Ile Gln Asn Val 
305                 310                 315                 320 


His Ala Ser Lys Arg Ile Leu Phe Ser Ile Val His Asp Lys Ser Glu 
                325                 330                 335     


Lys Trp Asp Ala Phe Ile Lys Glu Thr Glu Asp Ile Asn Thr Leu Arg 
            340                 345                 350         


Glu Cys Val Gln Ile Leu Phe Asn Ser Arg Tyr Ala Glu Ala Leu Gly 
        355                 360                 365             


Leu Asp His Met Val Pro Val Pro Tyr Arg Lys Ile Ala Cys Asp Pro 
    370                 375                 380                 


Glu Ala Val Glu Ile Val Gly Ile Pro Asp Lys Ile Pro Phe Lys Arg 
385                 390                 395                 400 


Pro Cys Thr Tyr Gly Val Pro Lys Leu Lys Arg Ile Leu Glu Glu Arg 
                405                 410                 415     


His Ser Ile His Phe Ile Ile Lys Arg Met Phe Asp Glu Arg Ile Phe 
            420                 425                 430         


Thr Gly Asn Lys Phe Thr Lys Asp Thr Thr Lys Leu Glu Pro Ala Ser 
        435                 440                 445             


Pro Pro Glu Asp Thr Ser Ala Glu Val Ser Arg Ala Thr Val Leu Asp 
    450                 455                 460                 


Leu Ala Gly Asn Ala Arg Ser Asp Lys Gly Ser Met Ser Glu Asp Cys 
465                 470                 475                 480 


Gly Pro Gly Thr Ser Gly Glu Leu Gly Gly Leu Arg Pro Ile Lys Ile 
                485                 490                 495     


Glu Pro Glu Asp Leu Asp Ile Ile Gln Val Thr Val Pro Asp Pro Ser 
            500                 505                 510         


Pro Thr Ser Glu Glu Met Thr Asp Ser Met Pro Gly His Leu Pro Ser 
        515                 520                 525             


Glu Asp Ser Gly Tyr Gly Met Glu Met Leu Thr Asp Lys Gly Leu Ser 
    530                 535                 540                 


Glu Asp Ala Arg Pro Glu Glu Arg Pro Val Glu Asp Ser His Gly Asp 
545                 550                 555                 560 


Val Ile Arg Pro Leu Arg Lys Gln Val Glu Leu Leu Phe Asn Thr Arg 
                565                 570                 575     


Tyr Ala Lys Ala Ile Gly Ile Ser Glu Pro Val Lys Val Pro Tyr Ser 
            580                 585                 590         


Lys Phe Leu Met His Pro Glu Glu Leu Phe Val Val Gly Leu Pro Glu 
        595                 600                 605             


Gly Ile Ser Leu Arg Arg Pro Asn Cys Phe Gly Ile Ala Lys Leu Arg 
    610                 615                 620                 


Lys Ile Leu Glu Ala Ser Asn Ser Ile Gln Phe Val Ile Lys Arg Pro 
625                 630                 635                 640 


Glu Leu Leu Thr Glu Gly Val Lys Glu Pro Ile Met Asp Ser Gln Gly 
                645                 650                 655     


Thr Ala Ser Ser Leu Gly Phe Ser Pro Pro Ala Leu Pro Pro Glu Arg 
            660                 665                 670         


Asp Ser Gly Asp Pro Leu Val Asp Glu Ser Leu Lys Arg Gln Gly Phe 
        675                 680                 685             


Gln Glu Asn Tyr Asp Ala Arg Leu Ser Arg Ile Asp Ile Ala Asn Thr 
    690                 695                 700                 


Leu Arg Glu Gln Val Gln Asp Leu Phe Asn Lys Lys Tyr Gly Glu Ala 
705                 710                 715                 720 


Leu Gly Ile Lys Tyr Pro Val Gln Val Pro Tyr Lys Arg Ile Lys Ser 
                725                 730                 735     


Asn Pro Gly Ser Val Ile Ile Glu Gly Leu Pro Pro Gly Ile Pro Phe 
            740                 745                 750         


Arg Lys Pro Cys Thr Phe Gly Ser Gln Asn Leu Glu Arg Ile Leu Ala 
        755                 760                 765             


Val Ala Asp Lys Ile Lys Phe Thr Val Thr Arg Pro Phe Gln Gly Leu 
    770                 775                 780                 


Ile Pro Lys Pro Asp Glu Asp Asp Ala Asn Arg Leu Gly Glu Lys Val 
785                 790                 795                 800 


Ile Leu Arg Glu Gln Val Lys Glu Leu Phe Asn Glu Lys Tyr Gly Glu 
                805                 810                 815     


Ala Leu Gly Leu Asn Arg Pro Val Leu Val Pro Tyr Lys Leu Ile Arg 
            820                 825                 830         


Asp Ser Pro Asp Ala Val Glu Val Thr Gly Leu Pro Asp Asp Ile Pro 
        835                 840                 845             


Phe Arg Asn Pro Asn Thr Tyr Asp Ile His Arg Leu Glu Lys Ile Leu 
    850                 855                 860                 


Lys Ala Arg Glu His Val Arg Met Val Ile Ile Asn Gln Leu Gln Pro 
865                 870                 875                 880 


Phe Ala Glu Ile Cys Asn Asp Ala Lys Val Pro Ala Lys Asp Ser Ser 
                885                 890                 895     


Ile Pro Lys Arg Lys Arg Lys Arg Val Ser Glu Gly Asn Ser Val Ser 
            900                 905                 910         


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Asn Pro Asp Ser Val 
        915                 920                 925             


Ala Ser Ala Asn Gln Ile Ser Leu Val Gln Trp Pro Met Tyr Met Val 
    930                 935                 940                 


Asp Tyr Ala Gly Leu Asn Val Gln Leu Pro Gly Pro Leu Asn Tyr 
945                 950                 955                 


<210>  3622
<211>  944
<212>  PRT
<213>  homo sapiens

<400>  3622

Met Ala Leu Leu Gly Lys Arg Cys Asp Val Pro Thr Asn Gly Cys Gly 
1               5                   10                  15      


Pro Asp Arg Trp Asn Ser Ala Phe Thr Arg Lys Asp Glu Ile Ile Thr 
            20                  25                  30          


Ser Leu Val Ser Ala Leu Asp Ser Met Cys Ser Ala Leu Ser Lys Leu 
        35                  40                  45              


Asn Ala Glu Val Ala Cys Val Ala Val His Asp Glu Ser Ala Phe Val 
    50                  55                  60                  


Val Gly Thr Glu Lys Gly Arg Met Phe Leu Asn Ala Arg Lys Glu Leu 
65                  70                  75                  80  


Gln Ser Asp Phe Leu Arg Phe Cys Arg Gly Pro Pro Trp Lys Asp Pro 
                85                  90                  95      


Glu Ala Glu His Pro Lys Lys Val Gln Arg Gly Glu Gly Gly Gly Arg 
            100                 105                 110         


Ser Leu Pro Arg Ser Ser Leu Glu His Gly Ser Asp Val Tyr Leu Leu 
        115                 120                 125             


Arg Lys Met Val Glu Glu Val Phe Asp Val Leu Tyr Ser Glu Ala Leu 
    130                 135                 140                 


Gly Arg Ala Ser Val Val Pro Leu Pro Tyr Glu Arg Leu Leu Arg Glu 
145                 150                 155                 160 


Pro Gly Leu Leu Ala Val Gln Gly Leu Pro Glu Gly Leu Ala Phe Arg 
                165                 170                 175     


Arg Pro Ala Glu Tyr Asp Pro Lys Ala Leu Met Ala Ile Leu Glu His 
            180                 185                 190         


Ser His Arg Ile Arg Phe Lys Leu Lys Arg Pro Leu Glu Asp Gly Gly 
        195                 200                 205             


Arg Asp Ser Lys Ala Leu Val Glu Leu Asn Gly Val Ser Leu Ile Pro 
    210                 215                 220                 


Lys Gly Ser Arg Asp Cys Gly Leu His Gly Gln Ala Pro Lys Val Pro 
225                 230                 235                 240 


Pro Gln Asp Leu Pro Pro Thr Ala Thr Ser Ser Ser Met Ala Ser Phe 
                245                 250                 255     


Leu Tyr Ser Thr Ala Leu Pro Asn His Ala Ile Arg Glu Leu Lys Gln 
            260                 265                 270         


Glu Ala Pro Ser Cys Pro Leu Ala Pro Ser Asp Leu Gly Leu Ser Arg 
        275                 280                 285             


Pro Met Pro Glu Pro Lys Ala Thr Gly Ala Gln Asp Phe Ser Asp Cys 
    290                 295                 300                 


Cys Gly Gln Lys Pro Thr Gly Pro Gly Gly Pro Leu Ile Gln Asn Val 
305                 310                 315                 320 


His Ala Ser Lys Arg Ile Leu Phe Ser Ile Val His Asp Lys Ser Glu 
                325                 330                 335     


Lys Trp Asp Ala Phe Ile Lys Glu Thr Glu Asp Ile Asn Thr Leu Arg 
            340                 345                 350         


Glu Cys Val Gln Ile Leu Phe Asn Ser Arg Tyr Ala Glu Ala Leu Gly 
        355                 360                 365             


Leu Asp His Met Val Pro Val Pro Tyr Arg Lys Ile Ala Cys Asp Pro 
    370                 375                 380                 


Glu Ala Val Glu Ile Val Gly Ile Pro Asp Lys Ile Pro Phe Lys Arg 
385                 390                 395                 400 


Pro Cys Thr Tyr Gly Val Pro Lys Leu Lys Arg Ile Leu Glu Glu Arg 
                405                 410                 415     


His Ser Ile His Phe Ile Ile Lys Arg Met Phe Asp Glu Arg Ile Phe 
            420                 425                 430         


Thr Gly Asn Lys Phe Thr Lys Asp Thr Thr Lys Leu Glu Pro Ala Ser 
        435                 440                 445             


Pro Pro Glu Asp Thr Ser Ala Glu Val Ser Arg Ala Thr Val Leu Asp 
    450                 455                 460                 


Leu Ala Gly Asn Ala Arg Ser Asp Lys Gly Ser Met Ser Glu Asp Cys 
465                 470                 475                 480 


Gly Pro Gly Thr Ser Gly Glu Leu Gly Gly Leu Arg Pro Ile Lys Ile 
                485                 490                 495     


Glu Pro Glu Asp Leu Asp Ile Ile Gln Val Thr Val Pro Asp Pro Ser 
            500                 505                 510         


Pro Thr Ser Glu Glu Met Thr Asp Ser Met Pro Gly His Leu Pro Ser 
        515                 520                 525             


Glu Asp Ser Gly Tyr Gly Met Glu Met Leu Thr Asp Lys Gly Leu Ser 
    530                 535                 540                 


Glu Asp Ala Arg Pro Glu Glu Arg Pro Val Glu Asp Ser His Gly Asp 
545                 550                 555                 560 


Val Ile Arg Pro Leu Arg Lys Gln Val Glu Leu Leu Phe Asn Thr Arg 
                565                 570                 575     


Tyr Ala Lys Ala Ile Gly Ile Ser Glu Pro Val Lys Val Pro Tyr Ser 
            580                 585                 590         


Lys Phe Leu Met His Pro Glu Glu Leu Phe Val Val Gly Leu Pro Glu 
        595                 600                 605             


Gly Ile Ser Leu Arg Arg Pro Asn Cys Phe Gly Ile Ala Lys Leu Arg 
    610                 615                 620                 


Lys Ile Leu Glu Ala Ser Asn Ser Ile Gln Phe Val Ile Lys Arg Pro 
625                 630                 635                 640 


Glu Leu Leu Thr Glu Gly Val Lys Glu Pro Ile Met Asp Ser Gln Glu 
                645                 650                 655     


Arg Asp Ser Gly Asp Pro Leu Val Asp Glu Ser Leu Lys Arg Gln Gly 
            660                 665                 670         


Phe Gln Glu Asn Tyr Asp Ala Arg Leu Ser Arg Ile Asp Ile Ala Asn 
        675                 680                 685             


Thr Leu Arg Glu Gln Val Gln Asp Leu Phe Asn Lys Lys Tyr Gly Glu 
    690                 695                 700                 


Ala Leu Gly Ile Lys Tyr Pro Val Gln Val Pro Tyr Lys Arg Ile Lys 
705                 710                 715                 720 


Ser Asn Pro Gly Ser Val Ile Ile Glu Gly Leu Pro Pro Gly Ile Pro 
                725                 730                 735     


Phe Arg Lys Pro Cys Thr Phe Gly Ser Gln Asn Leu Glu Arg Ile Leu 
            740                 745                 750         


Ala Val Ala Asp Lys Ile Lys Phe Thr Val Thr Arg Pro Phe Gln Gly 
        755                 760                 765             


Leu Ile Pro Lys Pro Asp Glu Asp Asp Ala Asn Arg Leu Gly Glu Lys 
    770                 775                 780                 


Val Ile Leu Arg Glu Gln Val Lys Glu Leu Phe Asn Glu Lys Tyr Gly 
785                 790                 795                 800 


Glu Ala Leu Gly Leu Asn Arg Pro Val Leu Val Pro Tyr Lys Leu Ile 
                805                 810                 815     


Arg Asp Ser Pro Asp Ala Val Glu Val Thr Gly Leu Pro Asp Asp Ile 
            820                 825                 830         


Pro Phe Arg Asn Pro Asn Thr Tyr Asp Ile His Arg Leu Glu Lys Ile 
        835                 840                 845             


Leu Lys Ala Arg Glu His Val Arg Met Val Ile Ile Asn Gln Leu Gln 
    850                 855                 860                 


Pro Phe Ala Glu Ile Cys Asn Asp Ala Lys Val Pro Ala Lys Asp Ser 
865                 870                 875                 880 


Ser Ile Pro Lys Arg Lys Arg Lys Arg Val Ser Glu Gly Asn Ser Val 
                885                 890                 895     


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Asn Pro Asp Ser 
            900                 905                 910         


Val Ala Ser Ala Asn Gln Ile Ser Leu Val Gln Trp Pro Met Tyr Met 
        915                 920                 925             


Val Asp Tyr Ala Gly Leu Asn Val Gln Leu Pro Gly Pro Leu Asn Tyr 
    930                 935                 940                 


<210>  3623
<211>  619
<212>  PRT
<213>  homo sapiens

<400>  3623

Met Tyr Gly Phe Val Asn His Ala Leu Glu Leu Leu Val Ile Arg Asn 
1               5                   10                  15      


Tyr Gly Pro Glu Val Trp Glu Asp Ile Lys Lys Glu Ala Gln Leu Asp 
            20                  25                  30          


Glu Glu Gly Gln Phe Leu Val Arg Ile Ile Tyr Asp Asp Ser Lys Thr 
        35                  40                  45              


Tyr Asp Leu Val Ala Ala Ala Ser Lys Val Leu Asn Leu Asn Ala Gly 
    50                  55                  60                  


Glu Ile Leu Gln Met Phe Gly Lys Met Phe Phe Val Phe Cys Gln Glu 
65                  70                  75                  80  


Ser Gly Tyr Asp Thr Ile Leu Arg Val Leu Gly Ser Asn Val Arg Glu 
                85                  90                  95      


Phe Leu Gln Asn Leu Asp Ala Leu His Asp His Leu Ala Thr Ile Tyr 
            100                 105                 110         


Pro Gly Met Arg Ala Pro Ser Phe Arg Cys Thr Asp Ala Glu Lys Gly 
        115                 120                 125             


Lys Gly Leu Ile Leu His Tyr Tyr Ser Glu Arg Glu Gly Leu Gln Asp 
    130                 135                 140                 


Ile Val Ile Gly Ile Ile Lys Thr Val Ala Gln Gln Ile His Gly Thr 
145                 150                 155                 160 


Glu Ile Asp Met Lys Val Ile Gln Gln Arg Asn Glu Glu Cys Asp His 
                165                 170                 175     


Thr Gln Phe Leu Ile Glu Glu Lys Glu Ser Lys Glu Glu Asp Phe Tyr 
            180                 185                 190         


Glu Asp Leu Asp Arg Phe Glu Glu Asn Gly Thr Gln Glu Ser Arg Ile 
        195                 200                 205             


Ser Pro Tyr Thr Phe Cys Lys Ala Phe Pro Phe His Ile Ile Phe Asp 
    210                 215                 220                 


Arg Asp Leu Val Val Thr Gln Cys Gly Asn Ala Ile Tyr Arg Val Leu 
225                 230                 235                 240 


Pro Gln Leu Gln Pro Gly Asn Cys Ser Leu Leu Ser Val Phe Ser Leu 
                245                 250                 255     


Val Arg Pro His Ile Asp Ile Ser Phe His Gly Ile Leu Ser His Ile 
            260                 265                 270         


Asn Thr Val Phe Val Leu Arg Ser Lys Glu Gly Leu Leu Asp Val Glu 
        275                 280                 285             


Lys Leu Glu Cys Glu Asp Glu Leu Thr Gly Thr Glu Ile Ser Cys Leu 
    290                 295                 300                 


Arg Leu Lys Gly Gln Met Ile Tyr Leu Pro Glu Ala Asp Ser Ile Leu 
305                 310                 315                 320 


Phe Leu Cys Ser Pro Ser Val Met Asn Leu Asp Asp Leu Thr Arg Arg 
                325                 330                 335     


Gly Leu Tyr Leu Ser Asp Ile Pro Leu His Asp Ala Thr Arg Asp Leu 
            340                 345                 350         


Val Leu Leu Gly Glu Gln Phe Arg Glu Glu Tyr Lys Leu Thr Gln Glu 
        355                 360                 365             


Leu Glu Ile Leu Thr Asp Arg Leu Gln Leu Thr Leu Arg Ala Leu Glu 
    370                 375                 380                 


Asp Glu Lys Lys Lys Thr Asp Thr Leu Leu Tyr Ser Val Leu Pro Pro 
385                 390                 395                 400 


Ser Val Ala Asn Glu Leu Arg His Lys Arg Pro Val Pro Ala Lys Arg 
                405                 410                 415     


Tyr Asp Asn Val Thr Ile Leu Phe Ser Gly Ile Val Gly Phe Asn Ala 
            420                 425                 430         


Phe Cys Ser Lys His Ala Ser Gly Glu Gly Ala Met Lys Ile Val Asn 
        435                 440                 445             


Leu Leu Asn Asp Leu Tyr Thr Arg Phe Asp Thr Leu Thr Asp Ser Arg 
    450                 455                 460                 


Lys Asn Pro Phe Val Tyr Lys Val Glu Thr Val Gly Asp Lys Tyr Met 
465                 470                 475                 480 


Thr Val Ser Gly Leu Pro Glu Pro Cys Ile His His Ala Arg Ser Ile 
                485                 490                 495     


Cys His Leu Ala Leu Asp Met Met Glu Ile Ala Gly Gln Val Gln Val 
            500                 505                 510         


Asp Gly Glu Ser Val Gln Ile Thr Ile Gly Ile His Thr Gly Glu Val 
        515                 520                 525             


Val Thr Gly Val Ile Gly Gln Arg Met Pro Arg Tyr Cys Leu Phe Gly 
    530                 535                 540                 


Asn Thr Val Asn Leu Thr Ser Arg Thr Glu Thr Thr Gly Glu Lys Gly 
545                 550                 555                 560 


Lys Ile Asn Val Ser Glu Tyr Thr Tyr Arg Cys Leu Met Ser Pro Glu 
                565                 570                 575     


Asn Ser Asp Pro Gln Phe His Leu Glu His Arg Gly Pro Val Ser Met 
            580                 585                 590         


Lys Gly Lys Lys Glu Pro Met Gln Val Trp Phe Leu Ser Arg Lys Asn 
        595                 600                 605             


Thr Gly Thr Glu Glu Thr Lys Gln Asp Asp Asp 
    610                 615                 


<210>  3624
<211>  470
<212>  PRT
<213>  homo sapiens

<400>  3624

Met Ser Val Thr Asp Gln Ala Phe Val Thr Leu Ala Thr Asn Asp Ile 
1               5                   10                  15      


Tyr Cys Gln Gly Ala Leu Val Leu Gly Gln Ser Leu Arg Arg His Arg 
            20                  25                  30          


Leu Thr Arg Lys Leu Val Val Leu Ile Thr Pro Gln Val Ser Ser Leu 
        35                  40                  45              


Leu Arg Val Ile Leu Ser Lys Val Phe Asp Glu Val Ile Glu Val Asn 
    50                  55                  60                  


Leu Ile Asp Ser Ala Asp Tyr Ile His Leu Ala Phe Leu Lys Arg Pro 
65                  70                  75                  80  


Glu Leu Gly Leu Thr Leu Thr Lys Leu His Cys Trp Thr Leu Thr His 
                85                  90                  95      


Tyr Ser Lys Cys Val Phe Leu Asp Ala Asp Thr Leu Val Leu Ser Asn 
            100                 105                 110         


Val Asp Glu Leu Phe Asp Arg Gly Glu Phe Ser Ala Ala Pro Asp Pro 
        115                 120                 125             


Gly Trp Pro Asp Cys Phe Asn Ser Gly Val Phe Val Phe Gln Pro Ser 
    130                 135                 140                 


Leu His Thr His Lys Leu Leu Leu Gln His Ala Met Glu His Gly Ser 
145                 150                 155                 160 


Phe Asp Gly Ala Asp Gln Gly Leu Leu Asn Ser Phe Phe Arg Asn Trp 
                165                 170                 175     


Ser Thr Thr Asp Ile His Lys His Leu Pro Phe Ile Tyr Asn Leu Ser 
            180                 185                 190         


Ser Asn Thr Met Tyr Thr Tyr Ser Pro Ala Phe Lys Gln Phe Gly Ser 
        195                 200                 205             


Ser Ala Lys Val Val His Phe Leu Gly Ser Met Lys Pro Trp Asn Tyr 
    210                 215                 220                 


Lys Tyr Asn Pro Gln Ser Gly Ser Val Leu Glu Gln Gly Ser Ala Ser 
225                 230                 235                 240 


Ser Ser Gln His Gln Ala Ala Phe Leu His Leu Trp Trp Thr Val Tyr 
                245                 250                 255     


Gln Asn Asn Val Leu Pro Leu Tyr Lys Ser Val Gln Ala Gly Glu Ala 
            260                 265                 270         


Arg Ala Ser Pro Gly His Thr Leu Cys His Ser Asp Val Gly Gly Pro 
        275                 280                 285             


Cys Ala Asp Ser Ala Ser Gly Val Gly Glu Pro Cys Glu Asn Ser Thr 
    290                 295                 300                 


Pro Ser Ala Gly Val Pro Cys Ala Asn Ser Pro Leu Gly Ser Asn Gln 
305                 310                 315                 320 


Pro Ala Gln Gly Leu Pro Glu Pro Thr Gln Ile Val Asp Glu Thr Leu 
                325                 330                 335     


Ser Leu Pro Glu Gly Arg Arg Ser Glu Asp Met Ile Ala Cys Pro Glu 
            340                 345                 350         


Thr Glu Thr Pro Ala Val Ile Thr Cys Asp Pro Leu Ser Gln Pro Ser 
        355                 360                 365             


Pro Gln Pro Ala Asp Phe Thr Glu Thr Glu Thr Ile Leu Gln Pro Ala 
    370                 375                 380                 


Asn Lys Val Glu Ser Val Ser Ser Glu Glu Thr Phe Glu Pro Ser Gln 
385                 390                 395                 400 


Glu Leu Pro Ala Glu Ala Leu Arg Asp Pro Ser Leu Gln Asp Ala Leu 
                405                 410                 415     


Glu Val Asp Leu Ala Val Ser Val Ser Gln Ile Ser Ile Glu Glu Lys 
            420                 425                 430         


Val Lys Glu Leu Ser Pro Glu Glu Glu Arg Arg Lys Trp Glu Glu Gly 
        435                 440                 445             


Arg Ile Asp Tyr Met Gly Lys Asp Ala Phe Ala Arg Ile Gln Glu Lys 
    450                 455                 460                 


Leu Asp Arg Phe Leu Gln 
465                 470 


<210>  3625
<211>  2249
<212>  PRT
<213>  homo sapiens

<400>  3625

Met Ala His Asn Ala Gly Ala Ala Ala Ala Ala Gly Thr His Ser Ala 
1               5                   10                  15      


Lys Ser Gly Gly Ser Glu Ala Ala Leu Lys Glu Gly Gly Ser Ala Ala 
            20                  25                  30          


Ala Leu Ser Ser Ser Ser Ser Ser Ser Ala Ala Ala Ala Ala Ala Ser 
        35                  40                  45              


Ser Ser Ser Ser Ser Gly Pro Gly Ser Ala Met Glu Thr Gly Leu Leu 
    50                  55                  60                  


Pro Asn His Lys Leu Lys Thr Val Gly Glu Ala Pro Ala Ala Pro Pro 
65                  70                  75                  80  


His Gln Gln His His His His His His Ala His His His His His His 
                85                  90                  95      


Ala His His Leu His His His His Ala Leu Gln Gln Gln Leu Asn Gln 
            100                 105                 110         


Phe Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln 
        115                 120                 125             


Gln Gln Gln His Pro Ile Ser Asn Asn Asn Ser Leu Gly Gly Ala Gly 
    130                 135                 140                 


Gly Gly Ala Pro Gln Pro Gly Pro Asp Met Glu Gln Pro Gln His Gly 
145                 150                 155                 160 


Gly Ala Lys Asp Ser Ala Ala Gly Gly Gln Ala Asp Pro Pro Gly Pro 
                165                 170                 175     


Pro Leu Leu Ser Lys Pro Gly Asp Glu Asp Asp Ala Pro Pro Lys Met 
            180                 185                 190         


Gly Glu Pro Ala Gly Gly Arg Tyr Glu His Pro Gly Leu Gly Ala Leu 
        195                 200                 205             


Gly Thr Gln Gln Pro Pro Val Ala Val Pro Gly Gly Gly Gly Gly Pro 
    210                 215                 220                 


Ala Ala Val Pro Glu Phe Asn Asn Tyr Tyr Gly Ser Ala Ala Pro Ala 
225                 230                 235                 240 


Ser Gly Gly Pro Gly Gly Arg Ala Gly Pro Cys Phe Asp Gln His Gly 
                245                 250                 255     


Gly Gln Gln Ser Pro Gly Met Gly Met Met His Ser Ala Ser Ala Ala 
            260                 265                 270         


Ala Ala Gly Ala Pro Gly Ser Met Asp Pro Leu Gln Asn Ser His Glu 
        275                 280                 285             


Gly Tyr Pro Asn Ser Gln Cys Asn His Tyr Pro Gly Tyr Ser Arg Pro 
    290                 295                 300                 


Gly Ala Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ser 
305                 310                 315                 320 


Gly Gly Gly Gly Gly Gly Gly Gly Ala Gly Ala Gly Gly Ala Gly Ala 
                325                 330                 335     


Gly Ala Val Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Gly Gly 
            340                 345                 350         


Gly Gly Gly Gly Gly Tyr Gly Gly Ser Ser Ala Gly Tyr Gly Val Leu 
        355                 360                 365             


Ser Ser Pro Arg Gln Gln Gly Gly Gly Met Met Met Gly Pro Gly Gly 
    370                 375                 380                 


Gly Gly Ala Ala Ser Leu Ser Lys Ala Ala Ala Gly Ser Ala Ala Gly 
385                 390                 395                 400 


Gly Phe Gln Arg Phe Ala Gly Gln Asn Gln His Pro Ser Gly Ala Thr 
                405                 410                 415     


Pro Thr Leu Asn Gln Leu Leu Thr Ser Pro Ser Pro Met Met Arg Ser 
            420                 425                 430         


Tyr Gly Gly Ser Tyr Pro Glu Tyr Ser Ser Pro Ser Ala Pro Pro Pro 
        435                 440                 445             


Pro Pro Ser Gln Pro Gln Ser Gln Ala Ala Ala Ala Gly Ala Ala Ala 
    450                 455                 460                 


Gly Gly Gln Gln Ala Ala Ala Gly Met Gly Leu Gly Lys Asp Met Gly 
465                 470                 475                 480 


Ala Gln Tyr Ala Ala Ala Ser Pro Ala Trp Ala Ala Ala Gln Gln Arg 
                485                 490                 495     


Ser His Pro Ala Met Ser Pro Gly Thr Pro Gly Pro Thr Met Gly Arg 
            500                 505                 510         


Ser Gln Gly Ser Pro Met Asp Pro Met Val Met Lys Arg Pro Gln Leu 
        515                 520                 525             


Tyr Gly Met Gly Ser Asn Pro His Ser Gln Pro Gln Gln Ser Ser Pro 
    530                 535                 540                 


Tyr Pro Gly Gly Ser Tyr Gly Pro Pro Gly Pro Gln Arg Tyr Pro Ile 
545                 550                 555                 560 


Gly Ile Gln Gly Arg Thr Pro Gly Ala Met Ala Gly Met Gln Tyr Pro 
                565                 570                 575     


Gln Gln Gln Asp Ser Gly Asp Ala Thr Trp Lys Glu Thr Phe Trp Leu 
            580                 585                 590         


Met Pro Pro Gln Tyr Gly Gln Gln Gly Val Ser Gly Tyr Cys Gln Gln 
        595                 600                 605             


Gly Gln Gln Pro Tyr Tyr Ser Gln Gln Pro Gln Pro Pro His Leu Pro 
    610                 615                 620                 


Pro Gln Ala Gln Tyr Leu Pro Ser Gln Ser Gln Gln Arg Tyr Gln Pro 
625                 630                 635                 640 


Gln Gln Asp Met Ser Gln Glu Gly Tyr Gly Thr Arg Ser Gln Pro Pro 
                645                 650                 655     


Leu Ala Pro Gly Lys Pro Asn His Glu Asp Leu Asn Leu Ile Gln Gln 
            660                 665                 670         


Glu Arg Pro Ser Ser Leu Pro Asp Leu Ser Gly Ser Ile Asp Asp Leu 
        675                 680                 685             


Pro Thr Gly Thr Glu Ala Thr Leu Ser Ser Ala Val Ser Ala Ser Gly 
    690                 695                 700                 


Ser Thr Ser Ser Gln Gly Asp Gln Ser Asn Pro Ala Gln Ser Pro Phe 
705                 710                 715                 720 


Ser Pro His Ala Ser Pro His Leu Ser Ser Ile Pro Gly Gly Pro Ser 
                725                 730                 735     


Pro Ser Pro Val Gly Ser Pro Val Gly Ser Asn Gln Ser Arg Ser Gly 
            740                 745                 750         


Pro Ile Ser Pro Ala Ser Ile Pro Gly Ser Gln Met Pro Pro Gln Pro 
        755                 760                 765             


Pro Gly Ser Gln Ser Glu Ser Ser Ser His Pro Ala Leu Ser Gln Ser 
    770                 775                 780                 


Pro Met Pro Gln Glu Arg Gly Phe Met Ala Gly Thr Gln Arg Asn Pro 
785                 790                 795                 800 


Gln Met Ala Gln Tyr Gly Pro Gln Gln Thr Gly Pro Ser Met Ser Pro 
                805                 810                 815     


His Pro Ser Pro Gly Gly Gln Met His Ala Gly Ile Ser Ser Phe Gln 
            820                 825                 830         


Gln Ser Asn Ser Ser Gly Thr Tyr Gly Pro Gln Met Ser Gln Tyr Gly 
        835                 840                 845             


Pro Gln Gly Asn Tyr Ser Arg Pro Pro Ala Tyr Ser Gly Val Pro Ser 
    850                 855                 860                 


Ala Ser Tyr Ser Gly Pro Gly Pro Gly Met Gly Ile Ser Ala Asn Asn 
865                 870                 875                 880 


Gln Met His Gly Gln Gly Pro Ser Gln Pro Cys Gly Ala Val Pro Leu 
                885                 890                 895     


Gly Arg Met Pro Ser Ala Gly Met Gln Asn Arg Pro Phe Pro Gly Asn 
            900                 905                 910         


Met Ser Ser Met Thr Pro Ser Ser Pro Gly Met Ser Gln Gln Gly Gly 
        915                 920                 925             


Pro Gly Met Gly Pro Pro Met Pro Thr Val Asn Arg Lys Ala Gln Glu 
    930                 935                 940                 


Ala Ala Ala Ala Val Met Gln Ala Ala Ala Asn Ser Ala Gln Ser Arg 
945                 950                 955                 960 


Gln Gly Ser Phe Pro Gly Met Asn Gln Ser Gly Leu Met Ala Ser Ser 
                965                 970                 975     


Ser Pro Tyr Ser Gln Pro Met Asn Asn Ser Ser Ser Leu Met Asn Thr 
            980                 985                 990         


Gln Ala Pro Pro Tyr Ser Met Ala  Pro Ala Met Val Asn  Ser Ser Ala 
        995                 1000                 1005             


Ala Ser  Val Gly Leu Ala Asp  Met Met Ser Pro Gly  Glu Ser Lys 
    1010                 1015                 1020             


Leu Pro  Leu Pro Leu Lys Ala  Asp Gly Lys Glu Glu  Gly Thr Pro 
    1025                 1030                 1035             


Gln Pro  Glu Ser Lys Ser Lys  Lys Ser Ser Ser Ser  Thr Thr Thr 
    1040                 1045                 1050             


Gly Glu  Lys Ile Thr Lys Val  Tyr Glu Leu Gly Asn  Glu Pro Glu 
    1055                 1060                 1065             


Arg Lys  Leu Trp Val Asp Arg  Tyr Leu Thr Phe Met  Glu Glu Arg 
    1070                 1075                 1080             


Gly Ser  Pro Val Ser Ser Leu  Pro Ala Val Gly Lys  Lys Pro Leu 
    1085                 1090                 1095             


Asp Leu  Phe Arg Leu Tyr Val  Cys Val Lys Glu Ile  Gly Gly Leu 
    1100                 1105                 1110             


Ala Gln  Val Asn Lys Asn Lys  Lys Trp Arg Glu Leu  Ala Thr Asn 
    1115                 1120                 1125             


Leu Asn  Val Gly Thr Ser Ser  Ser Ala Ala Ser Ser  Leu Lys Lys 
    1130                 1135                 1140             


Gln Tyr  Ile Gln Tyr Leu Phe  Ala Phe Glu Cys Lys  Ile Glu Arg 
    1145                 1150                 1155             


Gly Glu  Glu Pro Pro Pro Glu  Val Phe Ser Thr Gly  Asp Thr Lys 
    1160                 1165                 1170             


Lys Gln  Pro Lys Leu Gln Pro  Pro Ser Pro Ala Asn  Ser Gly Ser 
    1175                 1180                 1185             


Leu Gln  Gly Pro Gln Thr Pro  Gln Ser Thr Gly Ser  Asn Ser Met 
    1190                 1195                 1200             


Ala Glu  Val Pro Gly Asp Leu  Lys Pro Pro Thr Pro  Ala Ser Thr 
    1205                 1210                 1215             


Pro His  Gly Gln Met Thr Pro  Met Gln Gly Gly Arg  Ser Ser Thr 
    1220                 1225                 1230             


Ile Ser  Val His Asp Pro Phe  Ser Asp Val Ser Asp  Ser Ser Phe 
    1235                 1240                 1245             


Pro Lys  Arg Asn Ser Met Thr  Pro Asn Ala Pro Tyr  Gln Gln Gly 
    1250                 1255                 1260             


Met Ser  Met Pro Asp Val Met  Gly Arg Met Pro Tyr  Glu Pro Asn 
    1265                 1270                 1275             


Lys Asp  Pro Phe Gly Gly Met  Arg Lys Val Pro Gly  Ser Ser Glu 
    1280                 1285                 1290             


Pro Phe  Met Thr Gln Gly Gln  Met Pro Asn Ser Ser  Met Gln Asp 
    1295                 1300                 1305             


Met Tyr  Asn Gln Ser Pro Ser  Gly Ala Met Ser Asn  Leu Gly Met 
    1310                 1315                 1320             


Gly Gln  Arg Gln Gln Phe Pro  Tyr Gly Ala Ser Tyr  Asp Arg Arg 
    1325                 1330                 1335             


His Glu  Pro Tyr Gly Gln Gln  Tyr Pro Gly Gln Gly  Pro Pro Ser 
    1340                 1345                 1350             


Gly Gln  Pro Pro Tyr Gly Gly  His Gln Pro Gly Leu  Tyr Pro Gln 
    1355                 1360                 1365             


Gln Pro  Asn Tyr Lys Arg His  Met Asp Gly Met Tyr  Gly Pro Pro 
    1370                 1375                 1380             


Ala Lys  Arg His Glu Gly Asp  Met Tyr Asn Met Gln  Tyr Ser Ser 
    1385                 1390                 1395             


Gln Gln  Gln Glu Met Tyr Asn  Gln Tyr Gly Gly Ser  Tyr Ser Gly 
    1400                 1405                 1410             


Pro Asp  Arg Arg Pro Ile Gln  Gly Gln Tyr Pro Tyr  Pro Tyr Ser 
    1415                 1420                 1425             


Arg Glu  Arg Met Gln Gly Pro  Gly Gln Ile Gln Thr  His Gly Ile 
    1430                 1435                 1440             


Pro Pro  Gln Met Met Gly Gly  Pro Leu Gln Ser Ser  Ser Ser Glu 
    1445                 1450                 1455             


Gly Pro  Gln Gln Asn Met Trp  Ala Ala Arg Asn Asp  Met Pro Tyr 
    1460                 1465                 1470             


Pro Tyr  Gln Asn Arg Gln Gly  Pro Gly Gly Pro Thr  Gln Ala Pro 
    1475                 1480                 1485             


Pro Tyr  Pro Gly Met Asn Arg  Thr Asp Asp Met Met  Val Pro Asp 
    1490                 1495                 1500             


Gln Arg  Ile Asn His Glu Ser  Gln Trp Pro Ser His  Val Ser Gln 
    1505                 1510                 1515             


Arg Gln  Pro Tyr Met Ser Ser  Ser Ala Ser Met Gln  Pro Ile Thr 
    1520                 1525                 1530             


Arg Pro  Pro Gln Pro Ser Tyr  Gln Thr Pro Pro Ser  Leu Pro Asn 
    1535                 1540                 1545             


His Ile  Ser Arg Ala Pro Ser  Pro Ala Ser Phe Gln  Arg Ser Leu 
    1550                 1555                 1560             


Glu Asn  Arg Met Ser Pro Ser  Lys Ser Pro Phe Leu  Pro Ser Met 
    1565                 1570                 1575             


Lys Met  Gln Lys Val Met Pro  Thr Val Pro Thr Ser  Gln Val Thr 
    1580                 1585                 1590             


Gly Pro  Pro Pro Gln Pro Pro  Pro Ile Arg Arg Glu  Ile Thr Phe 
    1595                 1600                 1605             


Pro Pro  Gly Ser Val Glu Ala  Ser Gln Pro Val Leu  Lys Gln Arg 
    1610                 1615                 1620             


Arg Lys  Ile Thr Ser Lys Asp  Ile Val Thr Pro Glu  Ala Trp Arg 
    1625                 1630                 1635             


Val Met  Met Ser Leu Lys Ser  Gly Leu Leu Ala Glu  Ser Thr Trp 
    1640                 1645                 1650             


Ala Leu  Asp Thr Ile Asn Ile  Leu Leu Tyr Asp Asp  Ser Thr Val 
    1655                 1660                 1665             


Ala Thr  Phe Asn Leu Ser Gln  Leu Ser Gly Phe Leu  Glu Leu Leu 
    1670                 1675                 1680             


Val Glu  Tyr Phe Arg Lys Cys  Leu Ile Asp Ile Phe  Gly Ile Leu 
    1685                 1690                 1695             


Met Glu  Tyr Glu Val Gly Asp  Pro Ser Gln Lys Ala  Leu Asp His 
    1700                 1705                 1710             


Asn Ala  Ala Arg Lys Asp Asp  Ser Gln Ser Leu Ala  Asp Asp Ser 
    1715                 1720                 1725             


Gly Lys  Glu Glu Glu Asp Ala  Glu Cys Ile Asp Asp  Asp Glu Glu 
    1730                 1735                 1740             


Asp Glu  Glu Asp Glu Glu Glu  Asp Ser Glu Lys Thr  Glu Ser Asp 
    1745                 1750                 1755             


Glu Lys  Ser Ser Ile Ala Leu  Thr Ala Pro Asp Ala  Ala Ala Asp 
    1760                 1765                 1770             


Pro Lys  Glu Lys Pro Lys Gln  Ala Ser Lys Phe Asp  Lys Leu Pro 
    1775                 1780                 1785             


Ile Lys  Ile Val Lys Lys Asn  Asn Leu Phe Val Val  Asp Arg Ser 
    1790                 1795                 1800             


Asp Lys  Leu Gly Arg Val Gln  Glu Phe Asn Ser Gly  Leu Leu His 
    1805                 1810                 1815             


Trp Gln  Leu Gly Gly Gly Asp  Thr Thr Glu His Ile  Gln Thr His 
    1820                 1825                 1830             


Phe Glu  Ser Lys Met Glu Ile  Pro Pro Arg Arg Arg  Pro Pro Pro 
    1835                 1840                 1845             


Pro Leu  Ser Ser Ala Gly Arg  Lys Lys Glu Gln Glu  Gly Lys Gly 
    1850                 1855                 1860             


Asp Ser  Glu Glu Gln Gln Glu  Lys Ser Ile Ile Ala  Thr Ile Asp 
    1865                 1870                 1875             


Asp Val  Leu Ser Ala Arg Pro  Gly Ala Leu Pro Glu  Asp Ala Asn 
    1880                 1885                 1890             


Pro Gly  Pro Gln Thr Glu Ser  Ser Lys Phe Pro Phe  Gly Ile Gln 
    1895                 1900                 1905             


Gln Ala  Lys Ser His Arg Asn  Ile Lys Leu Leu Glu  Asp Glu Pro 
    1910                 1915                 1920             


Arg Ser  Arg Asp Glu Thr Pro  Leu Cys Thr Ile Ala  His Trp Gln 
    1925                 1930                 1935             


Asp Ser  Leu Ala Lys Arg Cys  Ile Cys Val Ser Asn  Ile Val Arg 
    1940                 1945                 1950             


Ser Leu  Ser Phe Val Pro Gly  Asn Asp Ala Glu Met  Ser Lys His 
    1955                 1960                 1965             


Pro Gly  Leu Val Leu Ile Leu  Gly Lys Leu Ile Leu  Leu His His 
    1970                 1975                 1980             


Glu His  Pro Glu Arg Lys Arg  Ala Pro Gln Thr Tyr  Glu Lys Glu 
    1985                 1990                 1995             


Glu Asp  Glu Asp Lys Gly Val  Ala Cys Ser Lys Asp  Glu Trp Trp 
    2000                 2005                 2010             


Trp Asp  Cys Leu Glu Val Leu  Arg Asp Asn Thr Leu  Val Thr Leu 
    2015                 2020                 2025             


Ala Asn  Ile Ser Gly Gln Leu  Asp Leu Ser Ala Tyr  Thr Glu Ser 
    2030                 2035                 2040             


Ile Cys  Leu Pro Ile Leu Asp  Gly Leu Leu His Trp  Met Val Cys 
    2045                 2050                 2055             


Pro Ser  Ala Glu Ala Gln Asp  Pro Phe Pro Thr Val  Gly Pro Asn 
    2060                 2065                 2070             


Ser Val  Leu Ser Pro Gln Arg  Leu Val Leu Glu Thr  Leu Cys Lys 
    2075                 2080                 2085             


Leu Ser  Ile Gln Asp Asn Asn  Val Asp Leu Ile Leu  Ala Thr Pro 
    2090                 2095                 2100             


Pro Phe  Ser Arg Gln Glu Lys  Phe Tyr Ala Thr Leu  Val Arg Tyr 
    2105                 2110                 2115             


Val Gly  Asp Arg Lys Asn Pro  Val Cys Arg Glu Met  Ser Met Ala 
    2120                 2125                 2130             


Leu Leu  Ser Asn Leu Ala Gln  Gly Asp Ala Leu Ala  Ala Arg Ala 
    2135                 2140                 2145             


Ile Ala  Val Gln Lys Gly Ser  Ile Gly Asn Leu Ile  Ser Phe Leu 
    2150                 2155                 2160             


Glu Asp  Gly Val Thr Met Ala  Gln Tyr Gln Gln Ser  Gln His Asn 
    2165                 2170                 2175             


Leu Met  His Met Gln Pro Pro  Pro Leu Glu Pro Pro  Ser Val Asp 
    2180                 2185                 2190             


Met Met  Cys Arg Ala Ala Lys  Ala Leu Leu Ala Met  Ala Arg Val 
    2195                 2200                 2205             


Asp Glu  Asn Arg Ser Glu Phe  Leu Leu His Glu Gly  Arg Leu Leu 
    2210                 2215                 2220             


Asp Ile  Ser Ile Ser Ala Val  Leu Asn Ser Leu Val  Ala Ser Val 
    2225                 2230                 2235             


Ile Cys  Asp Val Leu Phe Gln  Ile Gly Gln Leu 
    2240                 2245                 


<210>  3626
<211>  355
<212>  PRT
<213>  homo sapiens

<400>  3626

Met Ser Glu Glu Gln Phe Gly Gly Asp Gly Ala Ala Ala Ala Ala Thr 
1               5                   10                  15      


Ala Ala Val Gly Gly Ser Ala Gly Glu Gln Glu Gly Ala Met Val Ala 
            20                  25                  30          


Ala Thr Gln Gly Ala Ala Ala Ala Ala Gly Ser Gly Ala Gly Thr Gly 
        35                  40                  45              


Gly Gly Thr Ala Ser Gly Gly Thr Glu Gly Gly Ser Ala Glu Ser Glu 
    50                  55                  60                  


Gly Ala Lys Ile Asp Ala Ser Lys Asn Glu Glu Asp Glu Gly His Ser 
65                  70                  75                  80  


Asn Ser Ser Pro Arg His Ser Glu Ala Ala Thr Ala Gln Arg Glu Glu 
                85                  90                  95      


Trp Lys Met Phe Ile Gly Gly Leu Ser Trp Asp Thr Thr Lys Lys Asp 
            100                 105                 110         


Leu Lys Asp Tyr Phe Ser Lys Phe Gly Glu Val Val Asp Cys Thr Leu 
        115                 120                 125             


Lys Leu Asp Pro Ile Thr Gly Arg Ser Arg Gly Phe Gly Phe Val Leu 
    130                 135                 140                 


Phe Lys Glu Ser Glu Ser Val Asp Lys Val Met Asp Gln Lys Glu His 
145                 150                 155                 160 


Lys Leu Asn Gly Lys Val Ile Asp Pro Lys Arg Ala Lys Ala Met Lys 
                165                 170                 175     


Thr Lys Glu Pro Val Lys Lys Ile Phe Val Gly Gly Leu Ser Pro Asp 
            180                 185                 190         


Thr Pro Glu Glu Lys Ile Arg Glu Tyr Phe Gly Gly Phe Gly Glu Val 
        195                 200                 205             


Glu Ser Ile Glu Leu Pro Met Asp Asn Lys Thr Asn Lys Arg Arg Gly 
    210                 215                 220                 


Phe Cys Phe Ile Thr Phe Lys Glu Glu Glu Pro Val Lys Lys Ile Met 
225                 230                 235                 240 


Glu Lys Lys Tyr His Asn Val Gly Leu Ser Lys Cys Glu Ile Lys Val 
                245                 250                 255     


Ala Met Ser Lys Glu Gln Tyr Gln Gln Gln Gln Gln Trp Gly Ser Arg 
            260                 265                 270         


Gly Gly Phe Ala Gly Arg Ala Arg Gly Arg Gly Gly Gly Pro Ser Gln 
        275                 280                 285             


Asn Trp Asn Gln Gly Tyr Ser Asn Tyr Trp Asn Gln Gly Tyr Gly Asn 
    290                 295                 300                 


Tyr Gly Tyr Asn Ser Gln Gly Tyr Gly Gly Tyr Gly Gly Tyr Asp Tyr 
305                 310                 315                 320 


Thr Gly Tyr Asn Asn Tyr Tyr Gly Tyr Gly Asp Tyr Ser Asn Gln Gln 
                325                 330                 335     


Ser Gly Tyr Gly Lys Val Ser Arg Arg Gly Gly His Gln Asn Ser Tyr 
            340                 345                 350         


Lys Pro Tyr 
        355 


<210>  3627
<211>  1177
<212>  PRT
<213>  homo sapiens

<400>  3627

Met Asp Glu Pro Pro Phe Ser Glu Ala Ala Leu Glu Gln Ala Leu Gly 
1               5                   10                  15      


Glu Pro Cys Asp Leu Asp Ala Ala Leu Leu Thr Asp Ile Glu Gly Glu 
            20                  25                  30          


Val Gly Ala Gly Arg Gly Arg Ala Asn Gly Leu Asp Ala Pro Arg Ala 
        35                  40                  45              


Gly Ala Asp Arg Gly Ala Met Asp Cys Thr Phe Glu Asp Met Leu Gln 
    50                  55                  60                  


Leu Ile Asn Asn Gln Asp Ser Asp Phe Pro Gly Leu Phe Asp Pro Pro 
65                  70                  75                  80  


Tyr Ala Gly Ser Gly Ala Gly Gly Thr Asp Pro Ala Ser Pro Asp Thr 
                85                  90                  95      


Ser Ser Pro Gly Ser Leu Ser Pro Pro Pro Ala Thr Leu Ser Ser Ser 
            100                 105                 110         


Leu Glu Ala Phe Leu Ser Gly Pro Gln Ala Ala Pro Ser Pro Leu Ser 
        115                 120                 125             


Pro Pro Gln Pro Ala Pro Thr Pro Leu Lys Met Tyr Pro Ser Met Pro 
    130                 135                 140                 


Ala Phe Ser Pro Gly Pro Gly Ile Lys Glu Glu Ser Val Pro Leu Ser 
145                 150                 155                 160 


Ile Leu Gln Thr Pro Thr Pro Gln Pro Leu Pro Gly Ala Leu Leu Pro 
                165                 170                 175     


Gln Ser Phe Pro Ala Pro Ala Pro Pro Gln Phe Ser Ser Thr Pro Val 
            180                 185                 190         


Leu Gly Tyr Pro Ser Pro Pro Gly Gly Phe Ser Thr Gly Ser Pro Pro 
        195                 200                 205             


Gly Asn Thr Gln Gln Pro Leu Pro Gly Leu Pro Leu Ala Ser Pro Pro 
    210                 215                 220                 


Gly Val Pro Pro Val Ser Leu His Thr Gln Val Gln Ser Val Val Pro 
225                 230                 235                 240 


Gln Gln Leu Leu Thr Val Thr Ala Ala Pro Thr Ala Ala Pro Val Thr 
                245                 250                 255     


Thr Thr Val Thr Ser Gln Ile Gln Gln Val Pro Val Leu Leu Gln Pro 
            260                 265                 270         


His Phe Ile Lys Ala Asp Ser Leu Leu Leu Thr Ala Met Lys Thr Asp 
        275                 280                 285             


Gly Ala Thr Val Lys Ala Ala Gly Leu Ser Pro Leu Val Ser Gly Thr 
    290                 295                 300                 


Thr Val Gln Thr Gly Pro Leu Pro Thr Leu Val Ser Gly Gly Thr Ile 
305                 310                 315                 320 


Leu Ala Thr Val Pro Leu Val Val Asp Ala Glu Lys Leu Pro Ile Asn 
                325                 330                 335     


Arg Leu Ala Ala Gly Ser Lys Ala Pro Ala Ser Ala Gln Ser Arg Gly 
            340                 345                 350         


Glu Lys Arg Thr Ala His Asn Ala Ile Glu Lys Arg Tyr Arg Ser Ser 
        355                 360                 365             


Ile Asn Asp Lys Ile Ile Glu Leu Lys Asp Leu Val Val Gly Thr Glu 
    370                 375                 380                 


Ala Lys Leu Asn Lys Ser Ala Val Leu Arg Lys Ala Ile Asp Tyr Ile 
385                 390                 395                 400 


Arg Phe Leu Gln His Ser Asn Gln Lys Leu Lys Gln Glu Asn Leu Ser 
                405                 410                 415     


Leu Arg Thr Ala Val His Lys Ser Lys Ser Leu Lys Asp Leu Val Ser 
            420                 425                 430         


Ala Cys Gly Ser Gly Gly Asn Thr Asp Val Leu Met Glu Gly Val Lys 
        435                 440                 445             


Thr Glu Val Glu Asp Thr Leu Thr Pro Pro Pro Ser Asp Ala Gly Ser 
    450                 455                 460                 


Pro Phe Gln Ser Ser Pro Leu Ser Leu Gly Ser Arg Gly Ser Gly Ser 
465                 470                 475                 480 


Gly Gly Ser Gly Ser Asp Ser Glu Pro Asp Ser Pro Val Phe Glu Asp 
                485                 490                 495     


Ser Lys Ala Lys Pro Glu Gln Arg Pro Ser Leu His Ser Arg Gly Met 
            500                 505                 510         


Leu Asp Arg Ser Arg Leu Ala Leu Cys Thr Leu Val Phe Leu Cys Leu 
        515                 520                 525             


Ser Cys Asn Pro Leu Ala Ser Leu Leu Gly Ala Arg Gly Leu Pro Ser 
    530                 535                 540                 


Pro Ser Asp Thr Thr Ser Val Tyr His Ser Pro Gly Arg Asn Val Leu 
545                 550                 555                 560 


Gly Thr Glu Ser Arg Asp Gly Pro Gly Trp Ala Gln Trp Leu Leu Pro 
                565                 570                 575     


Pro Val Val Trp Leu Leu Asn Gly Leu Leu Val Leu Val Ser Leu Val 
            580                 585                 590         


Leu Leu Phe Val Tyr Gly Glu Pro Val Thr Arg Pro His Ser Gly Pro 
        595                 600                 605             


Ala Val Tyr Phe Trp Arg His Arg Lys Gln Ala Asp Leu Asp Leu Ala 
    610                 615                 620                 


Arg Gly Asp Phe Ala Gln Ala Ala Gln Gln Leu Trp Leu Ala Leu Arg 
625                 630                 635                 640 


Ala Leu Gly Arg Pro Leu Pro Thr Ser His Leu Asp Leu Ala Cys Ser 
                645                 650                 655     


Leu Leu Trp Asn Leu Ile Arg His Leu Leu Gln Arg Leu Trp Val Gly 
            660                 665                 670         


Arg Trp Leu Ala Gly Arg Ala Gly Gly Leu Gln Gln Asp Cys Ala Leu 
        675                 680                 685             


Arg Val Asp Ala Ser Ala Ser Ala Arg Asp Ala Ala Leu Val Tyr His 
    690                 695                 700                 


Lys Leu His Gln Leu His Thr Met Gly Lys His Thr Gly Gly His Leu 
705                 710                 715                 720 


Thr Ala Thr Asn Leu Ala Leu Ser Ala Leu Asn Leu Ala Glu Cys Ala 
                725                 730                 735     


Gly Asp Ala Val Ser Val Ala Thr Leu Ala Glu Ile Tyr Val Ala Ala 
            740                 745                 750         


Ala Leu Arg Val Lys Thr Ser Leu Pro Arg Ala Leu His Phe Leu Thr 
        755                 760                 765             


Arg Phe Phe Leu Ser Ser Ala Arg Gln Ala Cys Leu Ala Gln Ser Gly 
    770                 775                 780                 


Ser Val Pro Pro Ala Met Gln Trp Leu Cys His Pro Val Gly His Arg 
785                 790                 795                 800 


Phe Phe Val Asp Gly Asp Trp Ser Val Leu Ser Thr Pro Trp Glu Ser 
                805                 810                 815     


Leu Tyr Ser Leu Ala Gly Asn Pro Val Asp Pro Leu Ala Gln Val Thr 
            820                 825                 830         


Gln Leu Phe Arg Glu His Leu Leu Glu Arg Ala Leu Asn Cys Val Thr 
        835                 840                 845             


Gln Pro Asn Pro Ser Pro Gly Ser Ala Asp Gly Asp Lys Glu Phe Ser 
    850                 855                 860                 


Asp Ala Leu Gly Tyr Leu Gln Leu Leu Asn Ser Cys Ser Asp Ala Ala 
865                 870                 875                 880 


Gly Ala Pro Ala Tyr Ser Phe Ser Ile Ser Ser Ser Met Ala Thr Thr 
                885                 890                 895     


Thr Gly Val Asp Pro Val Ala Lys Trp Trp Ala Ser Leu Thr Ala Val 
            900                 905                 910         


Val Ile His Trp Leu Arg Arg Asp Glu Glu Ala Ala Glu Arg Leu Cys 
        915                 920                 925             


Pro Leu Val Glu His Leu Pro Arg Val Leu Gln Glu Ser Glu Arg Pro 
    930                 935                 940                 


Leu Pro Arg Ala Ala Leu His Ser Phe Lys Ala Ala Arg Ala Leu Leu 
945                 950                 955                 960 


Gly Cys Ala Lys Ala Glu Ser Gly Pro Ala Ser Leu Thr Ile Cys Glu 
                965                 970                 975     


Lys Ala Ser Gly Tyr Leu Gln Asp Ser Leu Ala Thr Thr Pro Ala Ser 
            980                 985                 990         


Ser Ser Ile Asp Lys Ala Val Gln  Leu Phe Leu Cys Asp  Leu Leu Leu 
        995                 1000                 1005             


Val Val  Arg Thr Ser Leu Trp  Arg Gln Gln Gln Pro  Pro Ala Pro 
    1010                 1015                 1020             


Ala Pro  Ala Ala Gln Gly Thr  Ser Ser Arg Pro Gln  Ala Ser Ala 
    1025                 1030                 1035             


Leu Glu  Leu Arg Gly Phe Gln  Arg Asp Leu Ser Ser  Leu Arg Arg 
    1040                 1045                 1050             


Leu Ala  Gln Ser Phe Arg Pro  Ala Met Arg Arg Val  Phe Leu His 
    1055                 1060                 1065             


Glu Ala  Thr Ala Arg Leu Met  Ala Gly Ala Ser Pro  Thr Arg Thr 
    1070                 1075                 1080             


His Gln  Leu Leu Asp Arg Ser  Leu Arg Arg Arg Ala  Gly Pro Gly 
    1085                 1090                 1095             


Gly Lys  Gly Gly Ala Val Ala  Glu Leu Glu Pro Arg  Pro Thr Arg 
    1100                 1105                 1110             


Arg Glu  His Ala Glu Ala Leu  Leu Leu Ala Ser Cys  Tyr Leu Pro 
    1115                 1120                 1125             


Pro Gly  Phe Leu Ser Ala Pro  Gly Gln Arg Val Gly  Met Leu Ala 
    1130                 1135                 1140             


Glu Ala  Ala Arg Thr Leu Glu  Lys Leu Gly Asp Arg  Arg Leu Leu 
    1145                 1150                 1155             


His Asp  Cys Gln Gln Met Leu  Met Arg Leu Gly Gly  Gly Thr Thr 
    1160                 1165                 1170             


Val Thr  Ser Ser 
    1175         


<210>  3628
<211>  300
<212>  PRT
<213>  homo sapiens

<400>  3628

Met Leu Pro Leu Leu Ala Ala Leu Leu Ala Ala Ala Cys Pro Leu Pro 
1               5                   10                  15      


Pro Val Arg Gly Gly Ala Ala Asp Ala Pro Gly Leu Leu Gly Val Pro 
            20                  25                  30          


Ser Asn Ala Ser Val Asn Ala Ser Ser Ala Asp Glu Pro Ile Ala Pro 
        35                  40                  45              


Arg Leu Leu Ala Ser Ala Ala Pro Gly Pro Pro Glu Arg Pro Gly Pro 
    50                  55                  60                  


Glu Glu Ala Ala Ala Ala Ala Ala Pro Cys Asn Ile Ser Val Gln Arg 
65                  70                  75                  80  


Gln Met Leu Ser Ser Leu Leu Val Arg Trp Gly Arg Pro Arg Gly Phe 
                85                  90                  95      


Gln Cys Asp Leu Leu Leu Phe Ser Thr Asn Ala His Gly Arg Ala Phe 
            100                 105                 110         


Phe Ala Ala Ala Phe His Arg Val Gly Pro Pro Leu Leu Ile Glu His 
        115                 120                 125             


Leu Gly Leu Ala Ala Gly Gly Ala Gln Gln Asp Leu Arg Leu Cys Val 
    130                 135                 140                 


Gly Cys Gly Trp Val Arg Gly Arg Arg Thr Gly Arg Leu Arg Pro Ala 
145                 150                 155                 160 


Ala Ala Pro Ser Ala Ala Ala Ala Thr Ala Gly Ala Pro Thr Ala Leu 
                165                 170                 175     


Pro Ala Tyr Pro Ala Ala Glu Pro Pro Gly Pro Leu Trp Leu Gln Gly 
            180                 185                 190         


Glu Pro Leu His Phe Cys Cys Leu Asp Phe Ser Leu Glu Glu Leu Gln 
        195                 200                 205             


Gly Glu Pro Gly Trp Arg Leu Asn Arg Lys Pro Ile Glu Ser Thr Leu 
    210                 215                 220                 


Val Ala Cys Phe Met Thr Leu Val Ile Val Val Trp Ser Val Ala Ala 
225                 230                 235                 240 


Leu Ile Trp Pro Val Pro Ile Ile Ala Gly Phe Leu Pro Asn Gly Met 
                245                 250                 255     


Glu Gln Arg Arg Thr Thr Ala Ser Thr Thr Ala Ala Thr Pro Ala Ala 
            260                 265                 270         


Val Pro Ala Gly Thr Thr Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala 
        275                 280                 285             


Ala Ala Ala Ala Val Thr Ser Gly Val Ala Thr Lys 
    290                 295                 300 


<210>  3629
<211>  289
<212>  PRT
<213>  homo sapiens

<400>  3629

Met Glu Pro Ala Ala Gly Ile Gln Arg Arg Ser Ser Gln Gly Pro Thr 
1               5                   10                  15      


Val Pro Pro Pro Pro Arg Gly His Ala Pro Pro Ala Ala Ala Pro Gly 
            20                  25                  30          


Pro Ala Pro Leu Ser Ser Pro Val Arg Glu Pro Pro Gln Leu Glu Glu 
        35                  40                  45              


Glu Arg Gln Val Arg Ile Ser Glu Ser Gly Gln Phe Ser Asp Gly Leu 
    50                  55                  60                  


Glu Asp Arg Gly Leu Leu Glu Ser Ser Thr Arg Leu Lys Pro His Glu 
65                  70                  75                  80  


Ala Gln Asn Tyr Arg Lys Lys Ala Leu Trp Val Ser Trp Phe Ser Ile 
                85                  90                  95      


Ile Val Thr Leu Ala Leu Ala Val Ala Ala Phe Thr Val Ser Val Met 
            100                 105                 110         


Arg Tyr Ser Ala Ser Ala Phe Gly Phe Ala Phe Asp Ala Ile Leu Asp 
        115                 120                 125             


Val Leu Ser Ser Ala Ile Val Leu Trp Arg Tyr Ser Asn Ala Ala Ala 
    130                 135                 140                 


Val His Ser Ala His Arg Glu Tyr Ile Ala Cys Val Ile Leu Gly Val 
145                 150                 155                 160 


Ile Phe Leu Leu Ser Ser Ile Cys Ile Val Val Lys Ala Ile His Asp 
                165                 170                 175     


Leu Ser Thr Arg Leu Leu Pro Glu Val Asp Asp Phe Leu Phe Ser Val 
            180                 185                 190         


Ser Ile Leu Ser Gly Ile Leu Cys Ser Ile Leu Ala Val Leu Lys Phe 
        195                 200                 205             


Met Leu Gly Lys Val Leu Thr Ser Arg Ala Leu Ile Thr Asp Gly Phe 
    210                 215                 220                 


Asn Ser Leu Val Gly Gly Val Met Gly Phe Ser Ile Leu Leu Ser Ala 
225                 230                 235                 240 


Glu Val Phe Lys His Asp Ser Ala Val Trp Tyr Leu Asp Gly Ser Ile 
                245                 250                 255     


Gly Val Leu Ile Gly Leu Thr Ile Phe Ala Tyr Gly Val Lys Leu Leu 
            260                 265                 270         


Ile Asp Met Val Pro Arg Val Arg Gln Thr Arg His Tyr Glu Met Phe 
        275                 280                 285             


Glu 
    


<210>  3630
<211>  856
<212>  PRT
<213>  homo sapiens

<400>  3630

Met Lys Ser Ala Arg Ala Lys Thr Pro Arg Lys Pro Thr Val Lys Lys 
1               5                   10                  15      


Gly Ser Gln Thr Asn Leu Lys Asp Pro Val Gly Val Tyr Cys Arg Val 
            20                  25                  30          


Arg Pro Leu Gly Phe Pro Asp Gln Glu Cys Cys Ile Glu Val Ile Asn 
        35                  40                  45              


Asn Thr Thr Val Gln Leu His Thr Pro Glu Gly Tyr Arg Leu Asn Arg 
    50                  55                  60                  


Asn Gly Asp Tyr Lys Glu Thr Gln Tyr Ser Phe Lys Gln Val Phe Gly 
65                  70                  75                  80  


Thr His Thr Thr Gln Lys Glu Leu Phe Asp Val Val Ala Asn Pro Leu 
                85                  90                  95      


Val Asn Asp Leu Ile His Gly Lys Asn Gly Leu Leu Phe Thr Tyr Gly 
            100                 105                 110         


Val Thr Gly Ser Gly Lys Thr His Thr Met Thr Gly Ser Pro Gly Glu 
        115                 120                 125             


Gly Gly Leu Leu Pro Arg Cys Leu Asp Met Ile Phe Asn Ser Ile Gly 
    130                 135                 140                 


Ser Phe Gln Ala Lys Arg Tyr Val Phe Lys Ser Asn Asp Arg Asn Ser 
145                 150                 155                 160 


Met Asp Ile Gln Cys Glu Val Asp Ala Leu Leu Glu Arg Gln Lys Arg 
                165                 170                 175     


Glu Ala Met Pro Asn Pro Lys Thr Ser Ser Ser Lys Arg Gln Val Asp 
            180                 185                 190         


Pro Glu Phe Ala Asp Met Ile Thr Val Gln Glu Phe Cys Lys Ala Glu 
        195                 200                 205             


Glu Val Asp Glu Asp Ser Val Tyr Gly Val Phe Val Ser Tyr Ile Glu 
    210                 215                 220                 


Ile Tyr Asn Asn Tyr Ile Tyr Asp Leu Leu Glu Glu Val Pro Phe Asp 
225                 230                 235                 240 


Pro Ile Lys Pro Lys Pro Pro Gln Ser Lys Leu Leu Arg Glu Asp Lys 
                245                 250                 255     


Asn His Asn Met Tyr Val Ala Gly Cys Thr Glu Val Glu Val Lys Ser 
            260                 265                 270         


Thr Glu Glu Ala Phe Glu Val Phe Trp Arg Gly Gln Lys Lys Arg Arg 
        275                 280                 285             


Ile Ala Asn Thr His Leu Asn Arg Glu Ser Ser Arg Ser His Ser Val 
    290                 295                 300                 


Phe Asn Ile Lys Leu Val Gln Ala Pro Leu Asp Ala Asp Gly Asp Asn 
305                 310                 315                 320 


Val Leu Gln Glu Lys Glu Gln Ile Thr Ile Ser Gln Leu Ser Leu Val 
                325                 330                 335     


Asp Leu Ala Gly Ser Glu Arg Thr Asn Arg Thr Arg Ala Glu Gly Asn 
            340                 345                 350         


Arg Leu Arg Glu Ala Gly Asn Ile Asn Gln Ser Leu Met Thr Leu Arg 
        355                 360                 365             


Thr Cys Met Asp Val Leu Arg Glu Asn Gln Met Tyr Gly Thr Asn Lys 
    370                 375                 380                 


Met Val Pro Tyr Arg Asp Ser Lys Leu Thr His Leu Phe Lys Asn Tyr 
385                 390                 395                 400 


Phe Asp Gly Glu Gly Lys Val Arg Met Ile Val Cys Val Asn Pro Lys 
                405                 410                 415     


Ala Glu Asp Tyr Glu Glu Asn Leu Gln Val Met Arg Phe Ala Glu Val 
            420                 425                 430         


Thr Gln Glu Val Glu Val Ala Arg Pro Val Asp Lys Ala Ile Cys Gly 
        435                 440                 445             


Leu Thr Pro Gly Arg Arg Tyr Arg Asn Gln Pro Arg Gly Pro Val Gly 
    450                 455                 460                 


Asn Glu Pro Leu Val Thr Asp Val Val Leu Gln Ser Phe Pro Pro Leu 
465                 470                 475                 480 


Pro Ser Cys Glu Ile Leu Asp Ile Asn Asp Glu Gln Thr Leu Pro Arg 
                485                 490                 495     


Leu Ile Glu Ala Leu Glu Lys Arg His Asn Leu Arg Gln Met Met Ile 
            500                 505                 510         


Asp Glu Phe Asn Lys Gln Ser Asn Ala Phe Lys Ala Leu Leu Gln Glu 
        515                 520                 525             


Phe Asp Asn Ala Val Leu Ser Lys Glu Asn His Met Gln Gly Lys Leu 
    530                 535                 540                 


Asn Glu Lys Glu Lys Met Ile Ser Gly Gln Lys Leu Glu Ile Glu Arg 
545                 550                 555                 560 


Leu Glu Lys Lys Asn Lys Thr Leu Glu Tyr Lys Ile Glu Ile Leu Glu 
                565                 570                 575     


Lys Thr Thr Thr Ile Tyr Glu Glu Asp Lys Arg Asn Leu Gln Gln Glu 
            580                 585                 590         


Leu Glu Thr Gln Asn Gln Lys Leu Gln Arg Gln Phe Ser Asp Lys Arg 
        595                 600                 605             


Arg Leu Glu Ala Arg Leu Gln Gly Met Val Thr Glu Thr Thr Met Lys 
    610                 615                 620                 


Trp Glu Lys Glu Cys Glu Arg Arg Val Ala Ala Lys Gln Leu Glu Met 
625                 630                 635                 640 


Gln Asn Lys Leu Trp Val Lys Asp Glu Lys Leu Lys Gln Leu Lys Ala 
                645                 650                 655     


Ile Val Thr Glu Pro Lys Thr Glu Lys Pro Glu Arg Pro Ser Arg Glu 
            660                 665                 670         


Arg Asp Arg Glu Lys Val Thr Gln Arg Ser Val Ser Pro Ser Pro Val 
        675                 680                 685             


Pro Leu Leu Phe Gln Pro Asp Gln Asn Ala Pro Pro Ile Arg Leu Arg 
    690                 695                 700                 


His Arg Arg Ser Arg Ser Ala Gly Asp Arg Trp Val Asp His Lys Pro 
705                 710                 715                 720 


Ala Ser Asn Met Gln Thr Glu Thr Val Met Gln Pro His Val Pro His 
                725                 730                 735     


Ala Ile Thr Val Ser Val Ala Asn Glu Lys Ala Leu Ala Lys Cys Glu 
            740                 745                 750         


Lys Tyr Met Leu Thr His Gln Glu Leu Ala Ser Asp Gly Glu Ile Glu 
        755                 760                 765             


Thr Lys Leu Ile Lys Gly Asp Ile Tyr Lys Thr Arg Gly Gly Gly Gln 
    770                 775                 780                 


Ser Val Gln Phe Thr Asp Ile Glu Thr Leu Lys Gln Glu Ser Pro Asn 
785                 790                 795                 800 


Gly Ser Arg Lys Arg Arg Ser Ser Thr Val Ala Pro Ala Gln Pro Asp 
                805                 810                 815     


Gly Ala Glu Ser Glu Trp Thr Asp Val Glu Thr Arg Cys Ser Val Ala 
            820                 825                 830         


Val Glu Met Arg Ala Gly Ser Gln Leu Gly Pro Gly Tyr Gln His His 
        835                 840                 845             


Ala Gln Pro Lys Arg Lys Lys Pro 
    850                 855     


<210>  3631
<211>  111
<212>  PRT
<213>  homo sapiens

<400>  3631

Met Ala Gly Lys Gln Ala Val Ser Ala Ser Gly Lys Trp Leu Asp Gly 
1               5                   10                  15      


Ile Arg Lys Trp Tyr Tyr Asn Ala Ala Gly Phe Asn Lys Leu Gly Leu 
            20                  25                  30          


Met Arg Asp Asp Thr Ile Tyr Glu Asp Glu Asp Val Lys Glu Ala Ile 
        35                  40                  45              


Arg Arg Leu Pro Glu Asn Leu Tyr Asn Asp Arg Met Phe Arg Ile Lys 
    50                  55                  60                  


Arg Ala Leu Asp Leu Asn Leu Lys His Gln Ile Leu Pro Lys Glu Gln 
65                  70                  75                  80  


Trp Thr Lys Tyr Glu Glu Glu Asn Phe Tyr Leu Glu Pro Tyr Leu Lys 
                85                  90                  95      


Glu Val Ile Arg Glu Arg Lys Glu Arg Glu Glu Trp Ala Lys Lys 
            100                 105                 110     


<210>  3632
<211>  387
<212>  PRT
<213>  homo sapiens

<400>  3632

Met Gly Ala Phe Leu Asp Lys Pro Lys Thr Glu Lys His Asn Ala His 
1               5                   10                  15      


Gly Ala Gly Asn Gly Leu Arg Tyr Gly Leu Ser Ser Met Gln Gly Trp 
            20                  25                  30          


Arg Val Glu Met Glu Asp Ala His Thr Ala Val Val Gly Ile Pro His 
        35                  40                  45              


Gly Leu Glu Asp Trp Ser Phe Phe Ala Val Tyr Asp Gly His Ala Gly 
    50                  55                  60                  


Ser Arg Val Ala Asn Tyr Cys Ser Thr His Leu Leu Glu His Ile Thr 
65                  70                  75                  80  


Thr Asn Glu Asp Phe Arg Ala Ala Gly Lys Ser Gly Ser Ala Leu Glu 
                85                  90                  95      


Leu Ser Val Glu Asn Val Lys Asn Gly Ile Arg Thr Gly Phe Leu Lys 
            100                 105                 110         


Ile Asp Glu Tyr Met Arg Asn Phe Ser Asp Leu Arg Asn Gly Met Asp 
        115                 120                 125             


Arg Ser Gly Ser Thr Ala Val Gly Val Met Ile Ser Pro Lys His Ile 
    130                 135                 140                 


Tyr Phe Ile Asn Cys Gly Asp Ser Arg Ala Val Leu Tyr Arg Asn Gly 
145                 150                 155                 160 


Gln Val Cys Phe Ser Thr Gln Asp His Lys Pro Cys Asn Pro Arg Glu 
                165                 170                 175     


Lys Glu Arg Ile Gln Asn Ala Gly Gly Ser Val Met Ile Gln Arg Val 
            180                 185                 190         


Asn Gly Ser Leu Ala Val Ser Arg Ala Leu Gly Asp Tyr Asp Tyr Lys 
        195                 200                 205             


Cys Val Asp Gly Lys Gly Pro Thr Glu Gln Leu Val Ser Pro Glu Pro 
    210                 215                 220                 


Glu Val Tyr Glu Ile Leu Arg Ala Glu Glu Asp Glu Phe Ile Ile Leu 
225                 230                 235                 240 


Ala Cys Asp Gly Ile Trp Asp Val Met Ser Asn Glu Glu Leu Cys Glu 
                245                 250                 255     


Tyr Val Lys Ser Arg Leu Glu Val Ser Asp Asp Leu Glu Asn Val Cys 
            260                 265                 270         


Asn Trp Val Val Asp Thr Cys Leu His Lys Gly Ser Arg Asp Asn Met 
        275                 280                 285             


Ser Ile Val Leu Val Cys Phe Ser Asn Ala Pro Lys Val Ser Asp Glu 
    290                 295                 300                 


Ala Val Lys Lys Asp Ser Glu Leu Asp Lys His Leu Glu Ser Arg Val 
305                 310                 315                 320 


Glu Glu Ile Met Glu Lys Ser Gly Glu Glu Gly Met Pro Asp Leu Ala 
                325                 330                 335     


His Val Met Arg Ile Leu Ser Ala Glu Asn Ile Pro Asn Leu Pro Pro 
            340                 345                 350         


Gly Gly Gly Leu Ala Gly Lys Arg Asn Val Ile Glu Ala Val Tyr Ser 
        355                 360                 365             


Arg Leu Asn Pro His Arg Glu Ser Asp Gly Gly Ala Gly Asp Leu Glu 
    370                 375                 380                 


Asp Pro Trp 
385         


<210>  3633
<211>  192
<212>  PRT
<213>  homo sapiens

<400>  3633

Met Ser Ile Val Leu Val Cys Phe Ser Asn Ala Pro Lys Val Ser Asp 
1               5                   10                  15      


Glu Ala Val Lys Lys Asp Ser Glu Leu Asp Lys His Leu Glu Ser Arg 
            20                  25                  30          


Val Glu Glu Ile Met Glu Lys Ser Gly Glu Glu Gly Met Pro Asp Leu 
        35                  40                  45              


Ala His Val Met Arg Ile Leu Ser Ala Glu Asn Ile Pro Asn Leu Pro 
    50                  55                  60                  


Pro Gly Gly Gly Leu Ala Gly Lys Arg Asn Val Ile Glu Ala Val Tyr 
65                  70                  75                  80  


Ser Arg Leu Asn Pro His Arg Glu Ser Asp Gly Ala Ser Asp Glu Ala 
                85                  90                  95      


Glu Glu Ser Gly Ser Gln Gly Lys Leu Val Glu Ala Leu Arg Gln Met 
            100                 105                 110         


Arg Ile Asn His Arg Gly Asn Tyr Arg Gln Leu Leu Glu Glu Met Leu 
        115                 120                 125             


Thr Ser Tyr Arg Leu Ala Lys Val Glu Gly Glu Glu Ser Pro Ala Glu 
    130                 135                 140                 


Pro Ala Ala Thr Ala Thr Ser Ser Asn Ser Asp Ala Gly Asn Pro Val 
145                 150                 155                 160 


Thr Met Gln Glu Ser His Thr Glu Ser Glu Ser Gly Leu Ala Glu Leu 
                165                 170                 175     


Asp Ser Ser Asn Glu Asp Ala Gly Thr Lys Met Ser Gly Glu Lys Ile 
            180                 185                 190         


<210>  3634
<211>  1312
<212>  PRT
<213>  homo sapiens

<400>  3634

Met Lys Ala Leu Asp Glu Pro Pro Tyr Leu Thr Val Gly Thr Asp Val 
1               5                   10                  15      


Ser Ala Lys Tyr Arg Gly Ala Phe Cys Glu Ala Lys Ile Lys Thr Ala 
            20                  25                  30          


Lys Arg Leu Val Lys Val Lys Val Thr Phe Arg His Asp Ser Ser Thr 
        35                  40                  45              


Val Glu Val Gln Asp Asp His Ile Lys Gly Pro Leu Lys Val Gly Ala 
    50                  55                  60                  


Ile Val Glu Val Lys Asn Leu Asp Gly Ala Tyr Gln Glu Ala Val Ile 
65                  70                  75                  80  


Asn Lys Leu Thr Asp Ala Ser Trp Tyr Thr Val Val Phe Asp Asp Gly 
                85                  90                  95      


Asp Glu Lys Thr Leu Arg Arg Ser Ser Leu Cys Leu Lys Gly Glu Arg 
            100                 105                 110         


His Phe Ala Glu Ser Glu Thr Leu Asp Gln Leu Pro Leu Thr Asn Pro 
        115                 120                 125             


Glu His Phe Gly Thr Pro Val Ile Gly Lys Lys Thr Asn Arg Gly Arg 
    130                 135                 140                 


Arg Ser Asn His Ile Pro Glu Glu Glu Ser Ser Ser Ser Ser Ser Asp 
145                 150                 155                 160 


Glu Asp Glu Asp Asp Arg Lys Gln Ile Asp Glu Leu Leu Gly Lys Val 
                165                 170                 175     


Val Cys Val Asp Tyr Ile Ser Leu Asp Lys Lys Lys Ala Leu Trp Phe 
            180                 185                 190         


Pro Ala Leu Val Val Cys Pro Asp Cys Ser Asp Glu Ile Ala Val Lys 
        195                 200                 205             


Lys Asp Asn Ile Leu Val Arg Ser Phe Lys Asp Gly Lys Phe Thr Ser 
    210                 215                 220                 


Val Pro Arg Lys Asp Val His Glu Ile Thr Ser Asp Thr Ala Pro Lys 
225                 230                 235                 240 


Pro Asp Ala Val Leu Lys Gln Ala Phe Glu Gln Ala Leu Glu Phe His 
                245                 250                 255     


Lys Ser Arg Thr Ile Pro Ala Asn Trp Lys Thr Glu Leu Lys Glu Asp 
            260                 265                 270         


Ser Ser Ser Ser Glu Ala Glu Glu Glu Glu Glu Glu Glu Asp Asp Glu 
        275                 280                 285             


Lys Glu Lys Glu Asp Asn Ser Ser Glu Glu Glu Glu Glu Ile Glu Pro 
    290                 295                 300                 


Phe Pro Glu Glu Arg Glu Asn Phe Leu Gln Gln Leu Tyr Lys Phe Met 
305                 310                 315                 320 


Glu Asp Arg Gly Thr Pro Ile Asn Lys Arg Pro Val Leu Gly Tyr Arg 
                325                 330                 335     


Asn Leu Asn Leu Phe Lys Leu Phe Arg Leu Val His Lys Leu Gly Gly 
            340                 345                 350         


Phe Asp Asn Ile Glu Ser Gly Ala Val Trp Lys Gln Val Tyr Gln Asp 
        355                 360                 365             


Leu Gly Ile Pro Val Leu Asn Ser Ala Ala Gly Tyr Asn Val Lys Cys 
    370                 375                 380                 


Ala Tyr Lys Lys Tyr Leu Tyr Gly Phe Glu Glu Tyr Cys Arg Ser Ala 
385                 390                 395                 400 


Asn Ile Glu Phe Gln Met Ala Leu Pro Glu Lys Val Val Asn Lys Gln 
                405                 410                 415     


Cys Lys Glu Cys Glu Asn Val Lys Glu Ile Lys Val Lys Glu Glu Asn 
            420                 425                 430         


Glu Thr Glu Ile Lys Glu Ile Lys Met Glu Glu Glu Arg Asn Ile Ile 
        435                 440                 445             


Pro Arg Glu Glu Lys Pro Ile Glu Asp Glu Ile Glu Arg Lys Glu Asn 
    450                 455                 460                 


Ile Lys Pro Ser Leu Gly Ser Lys Lys Asn Leu Leu Glu Ser Ile Pro 
465                 470                 475                 480 


Thr His Ser Asp Gln Glu Lys Glu Val Asn Ile Lys Lys Pro Glu Asp 
                485                 490                 495     


Asn Glu Asn Leu Asp Asp Lys Asp Asp Asp Thr Thr Arg Val Asp Glu 
            500                 505                 510         


Ser Leu Asn Ile Lys Val Glu Ala Glu Glu Glu Lys Ala Lys Ser Gly 
        515                 520                 525             


Asp Glu Thr Asn Lys Glu Glu Asp Glu Asp Asp Glu Glu Ala Glu Glu 
    530                 535                 540                 


Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp Glu Asp Asp Asp Asp Asn 
545                 550                 555                 560 


Asn Glu Glu Glu Glu Phe Glu Cys Tyr Pro Pro Gly Met Lys Val Gln 
                565                 570                 575     


Val Arg Tyr Gly Arg Gly Lys Asn Gln Lys Met Tyr Glu Ala Ser Ile 
            580                 585                 590         


Lys Asp Ser Asp Val Glu Gly Gly Glu Val Leu Tyr Leu Val His Tyr 
        595                 600                 605             


Cys Gly Trp Asn Val Arg Tyr Asp Glu Trp Ile Lys Ala Asp Lys Ile 
    610                 615                 620                 


Val Arg Pro Ala Asp Lys Asn Val Pro Lys Ile Lys His Arg Lys Lys 
625                 630                 635                 640 


Ile Lys Asn Lys Leu Asp Lys Glu Lys Asp Lys Asp Glu Lys Tyr Ser 
                645                 650                 655     


Pro Lys Asn Cys Lys Leu Arg Arg Leu Ser Lys Pro Pro Phe Gln Thr 
            660                 665                 670         


Asn Pro Ser Pro Glu Met Val Ser Lys Leu Asp Leu Thr Asp Ala Lys 
        675                 680                 685             


Asn Ser Asp Thr Ala His Ile Lys Ser Ile Glu Ile Thr Ser Ile Leu 
    690                 695                 700                 


Asn Gly Leu Gln Ala Ser Glu Ser Ser Ala Glu Asp Ser Glu Gln Glu 
705                 710                 715                 720 


Asp Glu Arg Gly Ala Gln Asp Met Asp Asn Asn Gly Lys Glu Glu Ser 
                725                 730                 735     


Lys Ile Asp His Leu Thr Asn Asn Arg Asn Asp Leu Ile Ser Lys Glu 
            740                 745                 750         


Glu Gln Asn Ser Ser Ser Leu Leu Glu Glu Asn Lys Val His Ala Asp 
        755                 760                 765             


Leu Val Ile Ser Lys Pro Val Ser Lys Ser Pro Glu Arg Leu Arg Lys 
    770                 775                 780                 


Asp Ile Glu Val Leu Ser Glu Asp Thr Asp Tyr Glu Glu Asp Glu Val 
785                 790                 795                 800 


Thr Lys Lys Arg Lys Asp Val Lys Lys Asp Thr Thr Asp Lys Ser Ser 
                805                 810                 815     


Lys Pro Gln Ile Lys Arg Gly Lys Arg Arg Tyr Cys Asn Thr Glu Glu 
            820                 825                 830         


Cys Leu Lys Thr Gly Ser Pro Gly Lys Lys Glu Glu Lys Ala Lys Asn 
        835                 840                 845             


Lys Glu Ser Leu Cys Met Glu Asn Ser Ser Asn Ser Ser Ser Asp Glu 
    850                 855                 860                 


Asp Glu Glu Glu Thr Lys Ala Lys Met Thr Pro Thr Lys Lys Tyr Asn 
865                 870                 875                 880 


Gly Leu Glu Glu Lys Arg Lys Ser Leu Arg Thr Thr Gly Phe Tyr Ser 
                885                 890                 895     


Gly Phe Ser Glu Val Ala Glu Lys Arg Ile Lys Leu Leu Asn Asn Ser 
            900                 905                 910         


Asp Glu Arg Leu Gln Asn Ser Arg Ala Lys Asp Arg Lys Asp Val Trp 
        915                 920                 925             


Ser Ser Ile Gln Gly Gln Trp Pro Lys Lys Thr Leu Lys Glu Leu Phe 
    930                 935                 940                 


Ser Asp Ser Asp Thr Glu Ala Ala Ala Ser Pro Pro His Pro Ala Pro 
945                 950                 955                 960 


Glu Glu Gly Val Ala Glu Glu Ser Leu Gln Thr Val Ala Glu Glu Glu 
                965                 970                 975     


Ser Cys Ser Pro Ser Val Glu Leu Glu Lys Pro Pro Pro Val Asn Val 
            980                 985                 990         


Asp Ser Lys Pro Ile Glu Glu Lys  Thr Val Glu Val Asn  Asp Arg Lys 
        995                 1000                 1005             


Ala Glu  Phe Pro Ser Ser Gly  Ser Asn Ser Val Leu  Asn Thr Pro 
    1010                 1015                 1020             


Pro Thr  Thr Pro Glu Ser Pro  Ser Ser Val Thr Val  Thr Glu Gly 
    1025                 1030                 1035             


Ser Arg  Gln Gln Ser Ser Val  Thr Val Ser Glu Pro  Leu Ala Pro 
    1040                 1045                 1050             


Asn Gln  Glu Glu Val Arg Ser  Ile Lys Ser Glu Thr  Asp Ser Thr 
    1055                 1060                 1065             


Ile Glu  Val Asp Ser Val Ala  Gly Glu Leu Gln Asp  Leu Gln Ser 
    1070                 1075                 1080             


Glu Gly  Asn Ser Ser Pro Ala  Gly Phe Asp Ala Ser  Val Ser Ser 
    1085                 1090                 1095             


Ser Ser  Ser Asn Gln Pro Glu  Pro Glu His Pro Glu  Lys Ala Cys 
    1100                 1105                 1110             


Thr Gly  Gln Lys Arg Val Lys  Asp Ala Gln Gly Gly  Gly Ser Ser 
    1115                 1120                 1125             


Ser Lys  Lys Gln Lys Arg Ser  His Lys Ala Thr Val  Val Asn Asn 
    1130                 1135                 1140             


Lys Lys  Lys Gly Lys Gly Thr  Asn Ser Ser Asp Ser  Glu Glu Leu 
    1145                 1150                 1155             


Ser Ala  Gly Glu Ser Ile Thr  Lys Ser Gln Pro Val  Lys Ser Val 
    1160                 1165                 1170             


Ser Thr  Gly Met Lys Ser His  Ser Thr Lys Ser Pro  Ala Arg Thr 
    1175                 1180                 1185             


Gln Ser  Pro Gly Lys Cys Gly  Lys Asn Gly Asp Lys  Asp Pro Asp 
    1190                 1195                 1200             


Leu Lys  Glu Pro Ser Asn Arg  Leu Pro Lys Val Tyr  Lys Trp Ser 
    1205                 1210                 1215             


Phe Gln  Met Ser Asp Leu Glu  Asn Met Thr Ser Ala  Glu Arg Ile 
    1220                 1225                 1230             


Thr Ile  Leu Gln Glu Lys Leu  Gln Glu Ile Arg Lys  His Tyr Leu 
    1235                 1240                 1245             


Ser Leu  Lys Ser Glu Val Ala  Ser Ile Asp Arg Arg  Arg Lys Arg 
    1250                 1255                 1260             


Leu Lys  Lys Lys Glu Arg Glu  Ser Ala Ala Thr Ser  Ser Ser Ser 
    1265                 1270                 1275             


Ser Ser  Pro Ser Ser Ser Ser  Ile Thr Ala Ala Val  Met Leu Thr 
    1280                 1285                 1290             


Leu Ala  Glu Pro Ser Met Ser  Ser Ala Ser Gln Asn  Gly Met Ser 
    1295                 1300                 1305             


Val Glu  Cys Arg 
    1310         


<210>  3635
<211>  707
<212>  PRT
<213>  homo sapiens

<400>  3635

Met Pro Glu Glu Ala Gly Phe Pro Pro Ala Lys Arg Phe Arg Pro Gly 
1               5                   10                  15      


Ser Gly Pro Pro Ser Arg Ala Gly Ser Phe Pro Pro Gly Arg Gln Val 
            20                  25                  30          


Val Met Leu Leu Thr Ala Gly Ser Gly Gly Arg Gly Gly Gly Gly Gly 
        35                  40                  45              


Arg Arg Gln Gln Pro Pro Leu Ala Gln Pro Ser Ala Ser Pro Tyr Pro 
    50                  55                  60                  


Glu Ala Val Glu Leu Gln Arg Arg Ser Leu Pro Ile Phe Gln Ala Arg 
65                  70                  75                  80  


Gly Gln Leu Leu Ala Gln Leu Arg Asn Leu Asp Asn Ala Val Leu Ile 
                85                  90                  95      


Gly Glu Thr Gly Ser Gly Lys Thr Thr Gln Ile Pro Gln Tyr Leu Tyr 
            100                 105                 110         


Glu Gly Gly Ile Ser Arg Gln Gly Ile Ile Ala Val Thr Gln Pro Arg 
        115                 120                 125             


Arg Val Ala Ala Ile Ser Leu Ala Thr Arg Val Ser Asp Glu Lys Arg 
    130                 135                 140                 


Thr Glu Leu Gly Lys Leu Val Gly Tyr Thr Val Arg Phe Asp Asp Val 
145                 150                 155                 160 


Thr Ser Glu Asp Thr Arg Ile Lys Phe Leu Thr Asp Gly Met Leu Leu 
                165                 170                 175     


Arg Glu Ala Ile Ser Asp Ser Leu Leu Arg Lys Tyr Ser Cys Val Ile 
            180                 185                 190         


Leu Asp Glu Ala His Glu Arg Thr Ile His Thr Asp Val Leu Phe Gly 
        195                 200                 205             


Val Val Lys Ala Ala Gln Lys Arg Arg Lys Glu Leu Gly Lys Leu Pro 
    210                 215                 220                 


Leu Lys Val Ile Val Met Ser Ala Thr Met Asp Val Asp Leu Phe Ser 
225                 230                 235                 240 


Gln Tyr Phe Asn Gly Ala Pro Val Leu Tyr Leu Glu Gly Arg Gln His 
                245                 250                 255     


Pro Ile Gln Val Phe Tyr Thr Lys Gln Pro Gln Asn Asp Tyr Leu His 
            260                 265                 270         


Ala Ala Leu Val Ser Val Phe Gln Ile His Gln Glu Ala Pro Ser Ser 
        275                 280                 285             


Gln Asp Ile Leu Val Phe Leu Thr Gly Gln Glu Glu Ile Glu Ala Met 
    290                 295                 300                 


Ser Lys Thr Cys Arg Asp Ile Ala Lys His Leu Pro Asp Gly Cys Pro 
305                 310                 315                 320 


Ala Met Leu Val Leu Pro Leu Tyr Ala Ser Leu Pro Tyr Ala Gln Gln 
                325                 330                 335     


Leu Arg Val Phe Gln Gly Ala Pro Lys Gly Tyr Arg Lys Val Ile Ile 
            340                 345                 350         


Ser Thr Asn Ile Ala Glu Thr Ser Ile Thr Ile Thr Gly Ile Lys Tyr 
        355                 360                 365             


Val Val Asp Thr Gly Met Val Lys Ala Lys Lys Tyr Asn Pro Asp Ser 
    370                 375                 380                 


Gly Leu Glu Val Leu Ala Val Gln Arg Val Ser Lys Thr Gln Ala Trp 
385                 390                 395                 400 


Gln Arg Thr Gly Arg Ala Gly Arg Glu Asp Ser Gly Ile Cys Tyr Arg 
                405                 410                 415     


Leu Tyr Thr Glu Asp Glu Phe Glu Lys Phe Asp Lys Met Thr Val Pro 
            420                 425                 430         


Glu Ile Gln Arg Cys Asn Leu Ala Ser Val Met Leu Gln Leu Leu Ala 
        435                 440                 445             


Met Lys Val Pro Asn Val Leu Thr Phe Asp Phe Met Ser Lys Pro Ser 
    450                 455                 460                 


Pro Asp His Ile Gln Ala Ala Ile Ala Gln Leu Asp Leu Leu Gly Ala 
465                 470                 475                 480 


Leu Glu His Lys Asp Asp Gln Leu Thr Leu Thr Pro Met Gly Arg Lys 
                485                 490                 495     


Met Ala Ala Phe Pro Leu Glu Pro Lys Phe Ala Lys Thr Ile Leu Met 
            500                 505                 510         


Ser Pro Lys Phe His Cys Thr Glu Glu Ile Leu Thr Ile Val Ser Leu 
        515                 520                 525             


Leu Ser Val Asp Ser Val Leu His Asn Pro Pro Ser Arg Arg Glu Glu 
    530                 535                 540                 


Val Gln Gly Val Arg Lys Lys Phe Ile Ser Ser Glu Gly Asp His Met 
545                 550                 555                 560 


Thr Leu Leu Asn Ile Tyr Arg Thr Phe Lys Asn Leu Gly Gly Asn Lys 
                565                 570                 575     


Asp Trp Cys Lys Glu Asn Phe Val Asn Ser Lys Asn Met Thr Leu Val 
            580                 585                 590         


Ala Glu Val Arg Ala Gln Leu Arg Asp Ile Cys Leu Lys Met Ser Met 
        595                 600                 605             


Pro Ile Ala Ser Ser Arg Gly Asp Val Glu Ser Val Arg Arg Cys Leu 
    610                 615                 620                 


Ala His Ser Leu Phe Met Ser Thr Ala Glu Leu Gln Pro Asp Gly Thr 
625                 630                 635                 640 


Tyr Ala Thr Thr Asp Thr His Gln Pro Val Ala Ile His Pro Ser Ser 
                645                 650                 655     


Val Leu Phe His Cys Lys Pro Ala Cys Val Val Tyr Thr Glu Leu Leu 
            660                 665                 670         


Tyr Thr Asn Lys Cys Tyr Met Arg Asp Leu Cys Val Ile Asp Ala Gln 
        675                 680                 685             


Trp Leu Tyr Glu Ala Ala Pro Glu Tyr Phe Arg Arg Lys Leu Arg Thr 
    690                 695                 700                 


Ala Arg Asn 
705         


<210>  3636
<211>  1008
<212>  PRT
<213>  homo sapiens

<400>  3636

Met Ser Tyr Asp Tyr His Gln Asn Trp Gly Arg Asp Gly Gly Pro Arg 
1               5                   10                  15      


Ser Ser Gly Gly Gly Tyr Gly Gly Gly Pro Ala Gly Gly His Gly Gly 
            20                  25                  30          


Asn Arg Gly Ser Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Arg Gly 
        35                  40                  45              


Gly Arg Gly Arg His Pro Gly His Leu Lys Gly Arg Glu Ile Gly Met 
    50                  55                  60                  


Trp Tyr Ala Lys Lys Gln Gly Gln Lys Asn Lys Glu Ala Glu Arg Gln 
65                  70                  75                  80  


Glu Arg Ala Val Val His Met Asp Glu Arg Arg Glu Glu Gln Ile Val 
                85                  90                  95      


Gln Leu Leu Asn Ser Val Gln Ala Lys Asn Asp Lys Glu Ser Glu Ala 
            100                 105                 110         


Gln Ile Ser Trp Phe Ala Pro Glu Asp His Gly Tyr Gly Thr Glu Val 
        115                 120                 125             


Ser Thr Lys Asn Thr Pro Cys Ser Glu Asn Lys Leu Asp Ile Gln Glu 
    130                 135                 140                 


Lys Lys Leu Ile Asn Gln Glu Lys Lys Met Phe Arg Ile Arg Asn Arg 
145                 150                 155                 160 


Ser Tyr Ile Asp Arg Asp Ser Glu Tyr Leu Leu Gln Glu Asn Glu Pro 
                165                 170                 175     


Asp Gly Thr Leu Asp Gln Lys Leu Leu Glu Asp Leu Gln Lys Lys Lys 
            180                 185                 190         


Asn Asp Leu Arg Tyr Ile Glu Met Gln His Phe Arg Glu Lys Leu Pro 
        195                 200                 205             


Ser Tyr Gly Met Gln Lys Glu Leu Val Asn Leu Ile Asp Asn His Gln 
    210                 215                 220                 


Val Thr Val Ile Ser Gly Glu Thr Gly Cys Gly Lys Thr Thr Gln Val 
225                 230                 235                 240 


Thr Gln Phe Ile Leu Asp Asn Tyr Ile Glu Arg Gly Lys Gly Ser Ala 
                245                 250                 255     


Cys Arg Ile Val Cys Thr Gln Pro Arg Arg Ile Ser Ala Ile Ser Val 
            260                 265                 270         


Ala Glu Arg Val Ala Ala Glu Arg Ala Glu Ser Cys Gly Ser Gly Asn 
        275                 280                 285             


Ser Thr Gly Tyr Gln Ile Arg Leu Gln Ser Arg Leu Pro Arg Lys Gln 
    290                 295                 300                 


Gly Ser Ile Leu Tyr Cys Thr Thr Gly Ile Ile Leu Gln Trp Leu Gln 
305                 310                 315                 320 


Ser Asp Pro Tyr Leu Ser Ser Val Ser His Ile Val Leu Asp Glu Ile 
                325                 330                 335     


His Glu Arg Asn Leu Gln Ser Asp Val Leu Met Thr Val Val Lys Asp 
            340                 345                 350         


Leu Leu Asn Phe Arg Ser Asp Leu Lys Val Ile Leu Met Ser Ala Thr 
        355                 360                 365             


Leu Asn Ala Glu Lys Phe Ser Glu Tyr Phe Gly Asn Cys Pro Met Ile 
    370                 375                 380                 


His Ile Pro Gly Phe Thr Phe Pro Val Val Glu Tyr Leu Leu Glu Asp 
385                 390                 395                 400 


Val Ile Glu Lys Ile Arg Tyr Val Pro Glu Gln Lys Glu His Arg Ser 
                405                 410                 415     


Gln Phe Lys Arg Gly Phe Met Gln Gly His Val Asn Arg Gln Glu Lys 
            420                 425                 430         


Glu Glu Lys Glu Ala Ile Tyr Lys Glu Arg Trp Pro Asp Tyr Val Arg 
        435                 440                 445             


Glu Leu Arg Arg Arg Tyr Ser Ala Ser Thr Val Asp Val Ile Glu Met 
    450                 455                 460                 


Met Glu Asp Asp Lys Val Asp Leu Asn Leu Ile Val Ala Leu Ile Arg 
465                 470                 475                 480 


Tyr Ile Val Leu Glu Glu Glu Asp Gly Ala Ile Leu Val Phe Leu Pro 
                485                 490                 495     


Gly Trp Asp Asn Ile Ser Thr Leu His Asp Leu Leu Met Ser Gln Val 
            500                 505                 510         


Met Phe Lys Ser Asp Lys Phe Leu Ile Ile Pro Leu His Ser Leu Met 
        515                 520                 525             


Pro Thr Val Asn Gln Thr Gln Val Phe Lys Arg Thr Pro Pro Gly Val 
    530                 535                 540                 


Arg Lys Ile Val Ile Ala Thr Asn Ile Ala Glu Thr Ser Ile Thr Ile 
545                 550                 555                 560 


Asp Asp Val Val Tyr Val Ile Asp Gly Gly Lys Ile Lys Glu Thr His 
                565                 570                 575     


Phe Asp Thr Gln Asn Asn Ile Ser Thr Met Ser Ala Glu Trp Val Ser 
            580                 585                 590         


Lys Ala Asn Ala Lys Gln Arg Lys Gly Arg Ala Gly Arg Val Gln Pro 
        595                 600                 605             


Gly His Cys Tyr His Leu Tyr Asn Gly Leu Arg Ala Ser Leu Leu Asp 
    610                 615                 620                 


Asp Tyr Gln Leu Pro Glu Ile Leu Arg Thr Pro Leu Glu Glu Leu Cys 
625                 630                 635                 640 


Leu Gln Ile Lys Ile Leu Arg Leu Gly Gly Ile Ala Tyr Phe Leu Ser 
                645                 650                 655     


Arg Leu Met Asp Pro Pro Ser Asn Glu Ala Val Leu Leu Ser Ile Arg 
            660                 665                 670         


His Leu Met Glu Leu Asn Ala Leu Asp Lys Gln Glu Glu Leu Thr Pro 
        675                 680                 685             


Leu Gly Val His Leu Ala Arg Leu Pro Val Glu Pro His Ile Gly Lys 
    690                 695                 700                 


Met Ile Leu Phe Gly Ala Leu Phe Cys Cys Leu Asp Pro Val Leu Thr 
705                 710                 715                 720 


Ile Ala Ala Ser Leu Ser Phe Lys Asp Pro Phe Val Ile Pro Leu Gly 
                725                 730                 735     


Lys Glu Lys Ile Ala Asp Ala Arg Arg Lys Glu Leu Ala Lys Asp Thr 
            740                 745                 750         


Arg Ser Asp His Leu Thr Val Val Asn Ala Phe Glu Gly Trp Glu Glu 
        755                 760                 765             


Ala Arg Arg Arg Gly Phe Arg Tyr Glu Lys Asp Tyr Cys Trp Glu Tyr 
    770                 775                 780                 


Phe Leu Ser Ser Asn Thr Leu Gln Met Leu His Asn Met Lys Gly Gln 
785                 790                 795                 800 


Phe Ala Glu His Leu Leu Gly Ala Gly Phe Val Ser Ser Arg Asn Pro 
                805                 810                 815     


Lys Asp Pro Glu Ser Asn Ile Asn Ser Asp Asn Glu Lys Ile Ile Lys 
            820                 825                 830         


Ala Val Ile Cys Ala Gly Leu Tyr Pro Lys Val Ala Lys Ile Arg Leu 
        835                 840                 845             


Asn Leu Gly Lys Lys Arg Lys Met Val Lys Val Tyr Thr Lys Thr Asp 
    850                 855                 860                 


Gly Leu Val Ala Val His Pro Lys Ser Val Asn Val Glu Gln Thr Asp 
865                 870                 875                 880 


Phe His Tyr Asn Trp Leu Ile Tyr His Leu Lys Met Arg Thr Ser Ser 
                885                 890                 895     


Ile Tyr Leu Tyr Asp Cys Thr Glu Val Ser Pro Tyr Cys Leu Leu Phe 
            900                 905                 910         


Phe Gly Gly Asp Ile Ser Ile Gln Lys Asp Asn Asp Gln Glu Thr Ile 
        915                 920                 925             


Ala Val Asp Glu Trp Ile Val Phe Gln Ser Pro Ala Arg Ile Ala His 
    930                 935                 940                 


Leu Val Lys Glu Leu Arg Lys Glu Leu Asp Ile Leu Leu Gln Glu Lys 
945                 950                 955                 960 


Ile Glu Ser Pro His Pro Val Asp Trp Asn Asp Thr Lys Ser Arg Asp 
                965                 970                 975     


Cys Ala Val Leu Ser Ala Ile Ile Asp Leu Ile Lys Thr Gln Glu Lys 
            980                 985                 990         


Ala Thr Pro Arg Asn Phe Pro Pro  Arg Phe Gln Asp Gly  Tyr Tyr Ser 
        995                 1000                 1005             


<210>  3637
<211>  285
<212>  PRT
<213>  homo sapiens

<400>  3637

Met Asp Pro Val Ser Gln Leu Ala Ser Ala Gly Thr Phe Arg Val Leu 
1               5                   10                  15      


Lys Glu Pro Leu Ala Phe Leu Arg Ala Leu Glu Leu Leu Phe Ala Ile 
            20                  25                  30          


Phe Ala Phe Ala Thr Cys Gly Gly Tyr Ser Gly Gly Leu Arg Leu Ser 
        35                  40                  45              


Val Asp Cys Val Asn Lys Thr Glu Ser Asn Leu Ser Ile Asp Ile Ala 
    50                  55                  60                  


Phe Ala Tyr Pro Phe Arg Leu His Gln Val Thr Phe Glu Val Pro Thr 
65                  70                  75                  80  


Cys Glu Gly Lys Glu Arg Gln Lys Leu Ala Leu Ile Gly Asp Ser Ser 
                85                  90                  95      


Ser Ser Ala Glu Phe Phe Val Thr Val Ala Val Phe Ala Phe Leu Tyr 
            100                 105                 110         


Ser Leu Ala Ala Thr Val Val Tyr Ile Phe Phe Gln Asn Lys Tyr Arg 
        115                 120                 125             


Glu Asn Asn Arg Gly Pro Leu Ile Asp Phe Ile Val Thr Val Val Phe 
    130                 135                 140                 


Ser Phe Leu Trp Leu Val Gly Ser Ser Ala Trp Ala Lys Gly Leu Ser 
145                 150                 155                 160 


Asp Val Lys Val Ala Thr Asp Pro Lys Glu Val Leu Leu Leu Met Ser 
                165                 170                 175     


Ala Cys Lys Gln Pro Ser Asn Lys Cys Met Ala Ile His Ser Pro Val 
            180                 185                 190         


Met Ser Ser Leu Asn Thr Ser Val Val Phe Gly Phe Leu Asn Phe Ile 
        195                 200                 205             


Leu Trp Ala Gly Asn Ile Trp Phe Val Phe Lys Glu Thr Gly Trp His 
    210                 215                 220                 


Ser Ser Gly Gln Arg Tyr Leu Ser Asp Pro Met Glu Lys His Ser Ser 
225                 230                 235                 240 


Ser Tyr Asn Gln Gly Gly Tyr Asn Gln Asp Ser Tyr Gly Ser Ser Ser 
                245                 250                 255     


Gly Tyr Ser Gln Gln Ala Ser Leu Gly Pro Thr Ser Asp Glu Phe Gly 
            260                 265                 270         


Gln Gln Pro Thr Gly Pro Thr Ser Phe Thr Asn Gln Ile 
        275                 280                 285 


<210>  3638
<211>  313
<212>  PRT
<213>  homo sapiens

<400>  3638

Met Leu Leu Leu Ala Asp Met Asp Val Val Asn Gln Leu Val Ala Gly 
1               5                   10                  15      


Gly Gln Phe Arg Val Val Lys Glu Pro Leu Gly Phe Val Lys Val Leu 
            20                  25                  30          


Gln Trp Val Phe Ala Ile Phe Ala Phe Ala Thr Cys Gly Ser Tyr Ser 
        35                  40                  45              


Gly Glu Leu Gln Leu Ser Val Asp Cys Ala Asn Lys Thr Glu Ser Asp 
    50                  55                  60                  


Leu Ser Ile Glu Val Glu Phe Glu Tyr Pro Phe Arg Leu His Gln Val 
65                  70                  75                  80  


Tyr Phe Asp Ala Pro Thr Cys Arg Gly Gly Thr Thr Lys Val Phe Leu 
                85                  90                  95      


Val Gly Asp Tyr Ser Ser Ser Ala Glu Phe Phe Val Thr Val Ala Val 
            100                 105                 110         


Phe Ala Phe Leu Tyr Ser Met Gly Ala Leu Ala Thr Tyr Ile Phe Leu 
        115                 120                 125             


Gln Asn Lys Tyr Arg Glu Asn Asn Lys Gly Pro Met Leu Asp Phe Leu 
    130                 135                 140                 


Ala Thr Ala Val Phe Ala Phe Met Trp Leu Val Ser Ser Ser Ala Trp 
145                 150                 155                 160 


Ala Lys Gly Leu Ser Asp Val Lys Met Ala Thr Asp Pro Glu Asn Ile 
                165                 170                 175     


Ile Lys Glu Met Pro Val Cys Arg Gln Thr Gly Asn Thr Cys Lys Glu 
            180                 185                 190         


Leu Arg Asp Pro Val Thr Ser Gly Leu Asn Thr Ser Val Val Phe Gly 
        195                 200                 205             


Phe Leu Asn Leu Val Leu Trp Val Gly Asn Leu Trp Phe Val Phe Lys 
    210                 215                 220                 


Glu Thr Gly Trp Ala Ala Pro Phe Leu Arg Ala Pro Pro Gly Ala Pro 
225                 230                 235                 240 


Glu Lys Gln Pro Ala Pro Gly Asp Ala Tyr Gly Asp Ala Gly Tyr Gly 
                245                 250                 255     


Gln Gly Pro Gly Gly Tyr Gly Pro Gln Asp Ser Tyr Gly Pro Gln Gly 
            260                 265                 270         


Gly Tyr Gln Pro Asp Tyr Gly Gln Pro Ala Gly Ser Gly Gly Ser Gly 
        275                 280                 285             


Tyr Gly Pro Gln Gly Asp Tyr Gly Gln Gln Gly Tyr Gly Pro Gln Gly 
    290                 295                 300                 


Ala Pro Thr Ser Phe Ser Asn Gln Met 
305                 310             


<210>  3639
<211>  425
<212>  PRT
<213>  homo sapiens

<400>  3639

Met Ala Pro Ile Thr Thr Ser Arg Glu Glu Phe Asp Glu Ile Pro Thr 
1               5                   10                  15      


Val Val Gly Ile Phe Ser Ala Phe Gly Leu Val Phe Thr Val Ser Leu 
            20                  25                  30          


Phe Ala Trp Ile Cys Cys Gln Arg Lys Ser Ser Lys Ser Asn Lys Thr 
        35                  40                  45              


Pro Pro Tyr Lys Phe Val His Val Leu Lys Gly Val Asp Ile Tyr Pro 
    50                  55                  60                  


Glu Asn Leu Asn Ser Lys Lys Lys Phe Gly Ala Asp Asp Lys Asn Glu 
65                  70                  75                  80  


Val Lys Asn Lys Pro Ala Val Pro Lys Asn Ser Leu His Leu Asp Leu 
                85                  90                  95      


Glu Lys Arg Asp Leu Asn Gly Asn Phe Pro Lys Thr Asn Leu Lys Pro 
            100                 105                 110         


Gly Ser Pro Ser Asp Leu Glu Asn Ala Thr Pro Lys Leu Phe Leu Glu 
        115                 120                 125             


Gly Glu Lys Glu Ser Val Ser Pro Glu Ser Leu Lys Ser Ser Thr Ser 
    130                 135                 140                 


Leu Thr Ser Glu Glu Lys Gln Glu Lys Leu Gly Thr Leu Phe Phe Ser 
145                 150                 155                 160 


Leu Glu Tyr Asn Phe Glu Arg Lys Ala Phe Val Val Asn Ile Lys Glu 
                165                 170                 175     


Ala Arg Gly Leu Pro Ala Met Asp Glu Gln Ser Met Thr Ser Asp Pro 
            180                 185                 190         


Tyr Ile Lys Met Thr Ile Leu Pro Glu Lys Lys His Lys Val Lys Thr 
        195                 200                 205             


Arg Val Leu Arg Lys Thr Leu Asp Pro Ala Phe Asp Glu Thr Phe Thr 
    210                 215                 220                 


Phe Tyr Gly Ile Pro Tyr Thr Gln Ile Gln Glu Leu Ala Leu His Phe 
225                 230                 235                 240 


Thr Ile Leu Ser Phe Asp Arg Phe Ser Arg Asp Asp Ile Ile Gly Glu 
                245                 250                 255     


Val Leu Ile Pro Leu Ser Gly Ile Glu Leu Ser Glu Gly Lys Met Leu 
            260                 265                 270         


Met Asn Arg Glu Ile Ile Lys Arg Asn Val Arg Lys Ser Ser Gly Arg 
        275                 280                 285             


Gly Glu Leu Leu Ile Ser Leu Cys Tyr Gln Ser Thr Thr Asn Thr Leu 
    290                 295                 300                 


Thr Val Val Val Leu Lys Ala Arg His Leu Pro Lys Ser Asp Val Ser 
305                 310                 315                 320 


Gly Leu Ser Asp Pro Tyr Val Lys Val Asn Leu Tyr His Ala Lys Lys 
                325                 330                 335     


Arg Ile Ser Lys Lys Lys Thr His Val Lys Lys Cys Thr Pro Asn Ala 
            340                 345                 350         


Val Phe Asn Glu Leu Phe Val Phe Asp Ile Pro Cys Glu Gly Leu Glu 
        355                 360                 365             


Asp Ile Ser Val Glu Phe Leu Val Leu Asp Ser Glu Arg Gly Ser Arg 
    370                 375                 380                 


Asn Glu Val Ile Gly Gln Leu Val Leu Gly Ala Ala Ala Glu Gly Thr 
385                 390                 395                 400 


Gly Gly Glu His Trp Lys Glu Ile Cys Asp Tyr Pro Arg Arg Gln Ile 
                405                 410                 415     


Ala Lys Trp His Val Leu Cys Asp Gly 
            420                 425 


<210>  3640
<211>  1026
<212>  PRT
<213>  homo sapiens

<400>  3640

Met Gly Gly Ser Gln Ser Leu Gln Pro Ala Pro Ala Ser Asp Leu Asn 
1               5                   10                  15      


Leu Glu Ala Ser Glu Ala Met Ser Ser Asp Ser Glu Glu Ala Phe Glu 
            20                  25                  30          


Thr Pro Glu Ser Thr Thr Pro Val Lys Ala Pro Pro Ala Pro Pro Pro 
        35                  40                  45              


Pro Pro Pro Glu Val Ile Pro Glu Pro Glu Val Ser Thr Gln Pro Pro 
    50                  55                  60                  


Pro Glu Glu Pro Gly Cys Gly Ser Glu Thr Val Pro Val Pro Asp Gly 
65                  70                  75                  80  


Pro Arg Ser Asp Ser Val Glu Gly Ser Pro Phe Arg Pro Pro Ser His 
                85                  90                  95      


Ser Phe Ser Ala Val Phe Asp Glu Asp Lys Pro Ile Ala Ser Ser Gly 
            100                 105                 110         


Thr Tyr Asn Leu Asp Phe Asp Asn Ile Glu Leu Val Asp Thr Phe Gln 
        115                 120                 125             


Thr Leu Glu Pro Arg Ala Ser Asp Ala Lys Asn Gln Glu Gly Lys Val 
    130                 135                 140                 


Asn Thr Arg Arg Lys Ser Thr Asp Ser Val Pro Ile Ser Lys Ser Thr 
145                 150                 155                 160 


Leu Ser Arg Ser Leu Ser Leu Gln Ala Ser Asp Phe Asp Gly Ala Ser 
                165                 170                 175     


Ser Ser Gly Asn Pro Glu Ala Val Ala Leu Ala Pro Asp Ala Tyr Ser 
            180                 185                 190         


Thr Gly Ser Ser Ser Ala Ser Ser Thr Leu Lys Arg Thr Lys Lys Pro 
        195                 200                 205             


Arg Pro Pro Ser Leu Lys Lys Lys Gln Thr Thr Lys Lys Pro Thr Glu 
    210                 215                 220                 


Thr Pro Pro Val Lys Glu Thr Gln Gln Glu Pro Asp Glu Glu Ser Leu 
225                 230                 235                 240 


Val Pro Ser Gly Glu Asn Leu Ala Ser Glu Thr Lys Thr Glu Ser Ala 
                245                 250                 255     


Lys Thr Glu Gly Pro Ser Pro Ala Leu Leu Glu Glu Thr Pro Leu Glu 
            260                 265                 270         


Pro Ala Val Gly Pro Lys Ala Ala Cys Pro Leu Asp Ser Glu Ser Ala 
        275                 280                 285             


Glu Gly Val Val Pro Pro Ala Ser Gly Gly Gly Arg Val Gln Asn Ser 
    290                 295                 300                 


Pro Pro Val Gly Arg Lys Thr Leu Pro Leu Thr Thr Ala Pro Glu Ala 
305                 310                 315                 320 


Gly Glu Val Thr Pro Ser Asp Ser Gly Gly Gln Glu Asp Ser Pro Ala 
                325                 330                 335     


Lys Gly Leu Ser Val Arg Leu Glu Phe Asp Tyr Ser Glu Asp Lys Ser 
            340                 345                 350         


Ser Trp Asp Asn Gln Gln Glu Asn Pro Pro Pro Thr Lys Lys Ile Gly 
        355                 360                 365             


Lys Lys Pro Val Ala Lys Met Pro Leu Arg Arg Pro Lys Met Lys Lys 
    370                 375                 380                 


Thr Pro Glu Lys Leu Asp Asn Thr Pro Ala Ser Pro Pro Arg Ser Pro 
385                 390                 395                 400 


Ala Glu Pro Asn Asp Ile Pro Ile Ala Lys Gly Thr Tyr Thr Phe Asp 
                405                 410                 415     


Ile Asp Lys Trp Asp Asp Pro Asn Phe Asn Pro Phe Ser Ser Thr Ser 
            420                 425                 430         


Lys Met Gln Glu Ser Pro Lys Leu Pro Gln Gln Ser Tyr Asn Phe Asp 
        435                 440                 445             


Pro Asp Thr Cys Asp Glu Ser Val Asp Pro Phe Lys Thr Ser Ser Lys 
    450                 455                 460                 


Thr Pro Ser Ser Pro Ser Lys Ser Pro Ala Ser Phe Glu Ile Pro Ala 
465                 470                 475                 480 


Ser Ala Met Glu Ala Asn Gly Val Asp Gly Asp Gly Leu Asn Lys Pro 
                485                 490                 495     


Ala Lys Lys Lys Lys Thr Pro Leu Lys Thr Asp Thr Phe Arg Val Lys 
            500                 505                 510         


Lys Ser Pro Lys Arg Ser Pro Leu Ser Asp Pro Pro Ser Gln Asp Pro 
        515                 520                 525             


Thr Pro Ala Ala Thr Pro Glu Thr Pro Pro Val Ile Ser Ala Val Val 
    530                 535                 540                 


His Ala Thr Asp Glu Glu Lys Leu Ala Val Thr Asn Gln Lys Trp Thr 
545                 550                 555                 560 


Cys Met Thr Val Asp Leu Glu Ala Asp Lys Gln Asp Tyr Pro Gln Pro 
                565                 570                 575     


Ser Asp Leu Ser Thr Phe Val Asn Glu Thr Lys Phe Ser Ser Pro Thr 
            580                 585                 590         


Glu Glu Leu Asp Tyr Arg Asn Ser Tyr Glu Ile Glu Tyr Met Glu Lys 
        595                 600                 605             


Ile Gly Ser Ser Leu Pro Gln Asp Asp Asp Ala Pro Lys Lys Gln Ala 
    610                 615                 620                 


Leu Tyr Leu Met Phe Asp Thr Ser Gln Glu Ser Pro Val Lys Ser Ser 
625                 630                 635                 640 


Pro Val Arg Met Ser Glu Ser Pro Thr Pro Cys Ser Gly Ser Ser Phe 
                645                 650                 655     


Glu Glu Thr Glu Ala Leu Val Asn Thr Ala Ala Lys Asn Gln His Pro 
            660                 665                 670         


Val Pro Arg Gly Leu Ala Pro Asn Gln Glu Ser His Leu Gln Val Pro 
        675                 680                 685             


Glu Lys Ser Ser Gln Lys Glu Leu Glu Ala Met Gly Leu Gly Thr Pro 
    690                 695                 700                 


Ser Glu Ala Ile Glu Ile Thr Ala Pro Glu Gly Ser Phe Ala Ser Ala 
705                 710                 715                 720 


Asp Ala Leu Leu Ser Arg Leu Ala His Pro Val Ser Leu Cys Gly Ala 
                725                 730                 735     


Leu Asp Tyr Leu Glu Pro Asp Leu Ala Glu Lys Asn Pro Pro Leu Phe 
            740                 745                 750         


Ala Gln Lys Leu Gln Glu Glu Leu Glu Phe Ala Ile Met Arg Ile Glu 
        755                 760                 765             


Ala Leu Lys Leu Ala Arg Gln Ile Ala Leu Ala Ser Arg Ser His Gln 
    770                 775                 780                 


Asp Ala Lys Arg Glu Ala Ala His Pro Thr Asp Val Ser Ile Ser Lys 
785                 790                 795                 800 


Thr Ala Leu Tyr Ser Arg Ile Gly Thr Ala Glu Val Glu Lys Pro Ala 
                805                 810                 815     


Gly Leu Leu Phe Gln Gln Pro Asp Leu Asp Ser Ala Leu Gln Ile Ala 
            820                 825                 830         


Arg Ala Glu Ile Ile Thr Lys Glu Arg Glu Val Ser Glu Trp Lys Asp 
        835                 840                 845             


Lys Tyr Glu Glu Ser Arg Arg Glu Val Met Glu Met Arg Lys Ile Val 
    850                 855                 860                 


Ala Glu Tyr Glu Lys Thr Ile Ala Gln Met Ile Glu Asp Glu Gln Arg 
865                 870                 875                 880 


Glu Lys Ser Val Ser His Gln Thr Val Gln Gln Leu Val Leu Glu Lys 
                885                 890                 895     


Glu Gln Ala Leu Ala Asp Leu Asn Ser Val Glu Lys Ser Leu Ala Asp 
            900                 905                 910         


Leu Phe Arg Arg Tyr Glu Lys Met Lys Glu Val Leu Glu Gly Phe Arg 
        915                 920                 925             


Lys Asn Glu Glu Val Leu Lys Arg Cys Ala Gln Glu Tyr Leu Ser Arg 
    930                 935                 940                 


Val Lys Lys Glu Glu Gln Arg Tyr Gln Ala Leu Lys Val His Ala Glu 
945                 950                 955                 960 


Glu Lys Leu Asp Arg Ala Asn Ala Glu Ile Ala Gln Val Arg Gly Lys 
                965                 970                 975     


Ala Gln Gln Glu Gln Ala Ala His Gln Ala Ser Leu Arg Lys Glu Gln 
            980                 985                 990         


Leu Arg Val Asp Ala Leu Glu Arg  Thr Leu Glu Gln Lys  Asn Lys Glu 
        995                 1000                 1005             


Ile Glu  Glu Leu Thr Lys Ile  Cys Asp Glu Leu Ile  Ala Lys Met 
    1010                 1015                 1020             


Gly Lys  Ser 
    1025     


<210>  3641
<211>  211
<212>  PRT
<213>  homo sapiens

<400>  3641

Met Glu Glu Leu Ser Ser Val Gly Glu Gln Val Phe Ala Ala Glu Cys 
1               5                   10                  15      


Ile Leu Ser Lys Arg Leu Arg Lys Gly Lys Leu Glu Tyr Leu Val Lys 
            20                  25                  30          


Trp Arg Gly Trp Ser Ser Lys His Asn Ser Trp Glu Pro Glu Glu Asn 
        35                  40                  45              


Ile Leu Asp Pro Arg Leu Leu Leu Ala Phe Gln Lys Lys Glu His Glu 
    50                  55                  60                  


Lys Glu Val Gln Asn Arg Lys Arg Gly Lys Arg Pro Arg Gly Arg Pro 
65                  70                  75                  80  


Arg Lys Leu Thr Ala Met Ser Ser Cys Ser Arg Arg Ser Lys Leu Lys 
                85                  90                  95      


Val Gly Gly Cys Ala Gly Tyr Ala Asp Pro Thr Ser Gln His Pro Leu 
            100                 105                 110         


Gly Val Gly Gly Arg Gln Arg Glu Gly Leu Gly Pro Ser Gly Arg Gly 
        115                 120                 125             


Trp His Phe Cys Gln Gln Ser Val Pro Leu Leu Gly Lys Gln Glu Pro 
    130                 135                 140                 


Pro Phe Phe Leu Ser Leu Ser Phe Cys Cys Gln Gly Pro Gln Pro Ala 
145                 150                 155                 160 


Glu Ser Ser Ser Pro Pro Leu Pro Gly Ala Ser Cys Phe Ser Leu Ser 
                165                 170                 175     


Cys Thr Pro Leu Cys Trp Val Ala Gly Ser Asn Cys Cys Arg Gln Ala 
            180                 185                 190         


Leu Phe Pro Pro Arg Gly Ser Leu Gly Asp Gly Lys Glu Gln Glu Ala 
        195                 200                 205             


Cys Val Gln 
    210     


<210>  3642
<211>  532
<212>  PRT
<213>  homo sapiens

<400>  3642

Met Glu Glu Leu Ser Ser Val Gly Glu Gln Val Phe Ala Ala Glu Cys 
1               5                   10                  15      


Ile Leu Ser Lys Arg Leu Arg Lys Gly Lys Leu Glu Tyr Leu Val Lys 
            20                  25                  30          


Trp Arg Gly Trp Ser Ser Lys His Asn Ser Trp Glu Pro Glu Glu Asn 
        35                  40                  45              


Ile Leu Asp Pro Arg Leu Leu Leu Ala Phe Gln Lys Lys Glu His Glu 
    50                  55                  60                  


Lys Glu Val Gln Asn Arg Lys Arg Gly Lys Arg Pro Arg Gly Arg Pro 
65                  70                  75                  80  


Arg Lys Leu Thr Ala Met Ser Ser Cys Ser Arg Arg Ser Lys Leu Lys 
                85                  90                  95      


Glu Pro Asp Ala Pro Ser Lys Ser Lys Ser Ser Ser Ser Ser Ser Ser 
            100                 105                 110         


Ser Thr Ser Ser Ser Ser Ser Ser Asp Glu Glu Asp Asp Ser Asp Leu 
        115                 120                 125             


Asp Ala Lys Arg Gly Pro Arg Gly Arg Glu Thr His Pro Val Pro Gln 
    130                 135                 140                 


Lys Lys Ala Gln Ile Leu Val Ala Lys Pro Glu Leu Lys Asp Pro Ile 
145                 150                 155                 160 


Arg Lys Lys Arg Gly Arg Lys Pro Leu Pro Pro Glu Gln Lys Ala Thr 
                165                 170                 175     


Arg Arg Pro Val Ser Leu Ala Lys Val Leu Lys Thr Ala Arg Lys Asp 
            180                 185                 190         


Leu Gly Ala Pro Ala Ser Lys Leu Pro Pro Pro Leu Ser Ala Pro Val 
        195                 200                 205             


Ala Gly Leu Ala Ala Leu Lys Ala His Ala Lys Glu Ala Cys Gly Gly 
    210                 215                 220                 


Pro Ser Ala Met Ala Thr Pro Glu Asn Leu Ala Ser Leu Met Lys Gly 
225                 230                 235                 240 


Met Ala Ser Ser Pro Gly Arg Gly Gly Ile Ser Trp Gln Ser Ser Ile 
                245                 250                 255     


Val His Tyr Met Asn Arg Met Thr Gln Ser Gln Ala Gln Ala Ala Ser 
            260                 265                 270         


Arg Leu Ala Leu Lys Ala Gln Ala Thr Asn Lys Cys Gly Leu Gly Leu 
        275                 280                 285             


Asp Leu Lys Val Arg Thr Gln Lys Gly Glu Leu Gly Met Ser Pro Pro 
    290                 295                 300                 


Gly Ser Lys Ile Pro Lys Ala Pro Ser Gly Gly Ala Val Glu Gln Lys 
305                 310                 315                 320 


Val Gly Asn Thr Gly Gly Pro Pro His Thr His Gly Ala Ser Arg Val 
                325                 330                 335     


Pro Ala Gly Cys Pro Gly Pro Gln Pro Ala Pro Thr Gln Glu Leu Ser 
            340                 345                 350         


Leu Gln Val Leu Asp Leu Gln Ser Val Lys Asn Gly Met Pro Gly Val 
        355                 360                 365             


Gly Leu Leu Ala Arg His Ala Thr Ala Thr Lys Gly Val Pro Ala Thr 
    370                 375                 380                 


Asn Pro Ala Pro Gly Lys Gly Thr Gly Ser Gly Leu Ile Gly Ala Ser 
385                 390                 395                 400 


Gly Ala Thr Met Pro Thr Asp Thr Ser Lys Ser Glu Lys Leu Ala Ser 
                405                 410                 415     


Arg Ala Val Ala Pro Pro Thr Pro Ala Ser Lys Arg Asp Cys Val Lys 
            420                 425                 430         


Gly Ser Ala Thr Pro Ser Gly Gln Glu Ser Arg Thr Ala Pro Gly Glu 
        435                 440                 445             


Ala Arg Lys Ala Ala Thr Leu Pro Glu Met Ser Ala Gly Glu Glu Ser 
    450                 455                 460                 


Ser Ser Ser Asp Ser Asp Pro Asp Ser Ala Ser Pro Pro Ser Thr Gly 
465                 470                 475                 480 


Gln Asn Pro Ser Val Ser Val Gln Thr Ser Gln Asp Trp Lys Pro Thr 
                485                 490                 495     


Arg Ser Leu Ile Glu His Val Phe Val Thr Asp Val Thr Ala Asn Leu 
            500                 505                 510         


Ile Thr Val Thr Val Lys Glu Ser Pro Thr Ser Val Gly Phe Phe Asn 
        515                 520                 525             


Leu Arg His Tyr 
    530         


<210>  3643
<211>  101
<212>  PRT
<213>  homo sapiens

<400>  3643

Met Ala Cys Pro Leu Glu Lys Ala Leu Asp Val Met Val Ser Thr Phe 
1               5                   10                  15      


His Lys Tyr Ser Gly Lys Glu Gly Asp Lys Phe Lys Leu Asn Lys Ser 
            20                  25                  30          


Glu Leu Lys Glu Leu Leu Thr Arg Glu Leu Pro Ser Phe Leu Gly Lys 
        35                  40                  45              


Arg Thr Asp Glu Ala Ala Phe Gln Lys Leu Met Ser Asn Leu Asp Ser 
    50                  55                  60                  


Asn Arg Asp Asn Glu Val Asp Phe Gln Glu Tyr Cys Val Phe Leu Ser 
65                  70                  75                  80  


Cys Ile Ala Met Met Cys Asn Glu Phe Phe Glu Gly Phe Pro Asp Lys 
                85                  90                  95      


Gln Pro Arg Lys Lys 
            100     


<210>  3644
<211>  439
<212>  PRT
<213>  homo sapiens

<400>  3644

Met Ala Glu Asp Val Ser Ser Ala Ala Pro Ser Pro Arg Gly Cys Ala 
1               5                   10                  15      


Asp Gly Arg Asp Ala Asp Pro Thr Glu Glu Gln Met Ala Glu Thr Glu 
            20                  25                  30          


Arg Asn Asp Glu Glu Gln Phe Glu Cys Gln Glu Leu Leu Glu Cys Gln 
        35                  40                  45              


Val Gln Val Gly Ala Pro Glu Glu Glu Glu Glu Glu Glu Glu Asp Ala 
    50                  55                  60                  


Gly Leu Val Ala Glu Ala Glu Ala Val Ala Ala Gly Trp Met Leu Asp 
65                  70                  75                  80  


Phe Leu Cys Leu Ser Leu Cys Arg Ala Phe Arg Asp Gly Arg Ser Glu 
                85                  90                  95      


Asp Phe Arg Arg Thr Arg Asn Ser Ala Glu Ala Ile Ile His Gly Leu 
            100                 105                 110         


Ser Ser Leu Thr Ala Cys Gln Leu Arg Thr Ile Tyr Ile Cys Gln Phe 
        115                 120                 125             


Leu Thr Arg Ile Ala Ala Gly Lys Thr Leu Asp Ala Gln Phe Glu Asn 
    130                 135                 140                 


Asp Glu Arg Ile Thr Pro Leu Glu Ser Ala Leu Met Ile Trp Gly Ser 
145                 150                 155                 160 


Ile Glu Lys Glu His Asp Lys Leu His Glu Glu Ile Gln Asn Leu Ile 
                165                 170                 175     


Lys Ile Gln Ala Ile Ala Val Cys Met Glu Asn Gly Asn Phe Lys Glu 
            180                 185                 190         


Ala Glu Glu Val Phe Glu Arg Ile Phe Gly Asp Pro Asn Ser His Met 
        195                 200                 205             


Pro Phe Lys Ser Lys Leu Leu Met Ile Ile Ser Gln Lys Asp Thr Phe 
    210                 215                 220                 


His Ser Phe Phe Gln His Phe Ser Tyr Asn His Met Met Glu Lys Ile 
225                 230                 235                 240 


Lys Ser Tyr Val Asn Tyr Val Leu Ser Glu Lys Ser Ser Thr Phe Leu 
                245                 250                 255     


Met Lys Ala Ala Ala Lys Val Val Glu Ser Lys Arg Thr Arg Thr Ile 
            260                 265                 270         


Thr Ser Gln Asp Lys Pro Ser Gly Asn Asp Val Glu Met Glu Thr Glu 
        275                 280                 285             


Ala Asn Leu Asp Thr Arg Lys Ser Val Ser Asp Lys Gln Ser Ala Val 
    290                 295                 300                 


Thr Glu Ser Ser Glu Gly Thr Val Ser Leu Leu Arg Ser His Lys Asn 
305                 310                 315                 320 


Leu Phe Leu Ser Lys Leu Gln His Gly Thr Gln Gln Gln Asp Leu Asn 
                325                 330                 335     


Lys Lys Glu Arg Arg Val Gly Thr Pro Gln Ser Thr Lys Lys Lys Lys 
            340                 345                 350         


Glu Ser Arg Arg Ala Thr Glu Ser Arg Ile Pro Val Ser Lys Ser Gln 
        355                 360                 365             


Pro Val Thr Pro Glu Lys His Arg Ala Arg Lys Arg Gln Ala Trp Leu 
    370                 375                 380                 


Trp Glu Glu Asp Lys Asn Leu Arg Ser Gly Val Arg Lys Tyr Gly Glu 
385                 390                 395                 400 


Gly Asn Trp Ser Lys Ile Leu Leu His Tyr Lys Phe Asn Asn Arg Thr 
                405                 410                 415     


Ser Val Met Leu Lys Asp Arg Trp Arg Thr Met Lys Lys Leu Lys Leu 
            420                 425                 430         


Ile Ser Ser Asp Ser Glu Asp 
        435                 


<210>  3645
<211>  811
<212>  PRT
<213>  homo sapiens

<400>  3645

Met Glu Ala Ala Arg Ala Leu Arg Leu Leu Leu Val Val Cys Gly Cys 
1               5                   10                  15      


Leu Ala Leu Pro Pro Leu Ala Glu Pro Val Cys Pro Glu Arg Cys Asp 
            20                  25                  30          


Cys Gln His Pro Gln His Leu Leu Cys Thr Asn Arg Gly Leu Arg Val 
        35                  40                  45              


Val Pro Lys Thr Ser Ser Leu Pro Ser Pro His Asp Val Leu Thr Tyr 
    50                  55                  60                  


Ser Leu Gly Gly Asn Phe Ile Thr Asn Ile Thr Ala Phe Asp Phe His 
65                  70                  75                  80  


Arg Leu Gly Gln Leu Arg Arg Leu Asp Leu Gln Tyr Asn Gln Ile Arg 
                85                  90                  95      


Ser Leu His Pro Lys Thr Phe Glu Lys Leu Ser Arg Leu Glu Glu Leu 
            100                 105                 110         


Tyr Leu Gly Asn Asn Leu Leu Gln Ala Leu Ala Pro Gly Thr Leu Ala 
        115                 120                 125             


Pro Leu Arg Lys Leu Arg Ile Leu Tyr Ala Asn Gly Asn Glu Ile Ser 
    130                 135                 140                 


Arg Leu Ser Arg Gly Ser Phe Glu Gly Leu Glu Ser Leu Val Lys Leu 
145                 150                 155                 160 


Arg Leu Asp Gly Asn Ala Leu Gly Ala Leu Pro Asp Ala Val Phe Ala 
                165                 170                 175     


Pro Leu Gly Asn Leu Leu Tyr Leu His Leu Glu Ser Asn Arg Ile Arg 
            180                 185                 190         


Phe Leu Gly Lys Asn Ala Phe Ala Gln Leu Gly Lys Leu Arg Phe Leu 
        195                 200                 205             


Asn Leu Ser Ala Asn Glu Leu Gln Pro Ser Leu Arg His Ala Ala Thr 
    210                 215                 220                 


Phe Ala Pro Leu Arg Ser Leu Ser Ser Leu Ile Leu Ser Ala Asn Asn 
225                 230                 235                 240 


Leu Gln His Leu Gly Pro Arg Ile Phe Gln His Leu Pro Arg Leu Gly 
                245                 250                 255     


Leu Leu Ser Leu Arg Gly Asn Gln Leu Thr His Leu Ala Pro Glu Ala 
            260                 265                 270         


Phe Trp Gly Leu Glu Ala Leu Arg Glu Leu Arg Leu Glu Gly Asn Arg 
        275                 280                 285             


Leu Ser Gln Leu Pro Thr Ala Leu Leu Glu Pro Leu His Ser Leu Glu 
    290                 295                 300                 


Ala Leu Asp Leu Ser Gly Asn Glu Leu Ser Ala Leu His Pro Ala Thr 
305                 310                 315                 320 


Phe Gly His Leu Gly Arg Leu Arg Glu Leu Ser Leu Arg Asn Asn Ala 
                325                 330                 335     


Leu Ser Ala Leu Ser Gly Asp Ile Phe Ala Ala Ser Pro Ala Leu Tyr 
            340                 345                 350         


Arg Leu Asp Leu Asp Gly Asn Gly Trp Thr Cys Asp Cys Arg Leu Arg 
        355                 360                 365             


Gly Leu Lys Arg Trp Met Gly Asp Trp His Ser Gln Gly Arg Leu Leu 
    370                 375                 380                 


Thr Val Phe Val Gln Cys Arg His Pro Pro Ala Leu Arg Gly Lys Tyr 
385                 390                 395                 400 


Leu Asp Tyr Leu Asp Asp Gln Gln Leu Gln Asn Gly Ser Cys Ala Asp 
                405                 410                 415     


Pro Ser Pro Ser Ala Ser Leu Thr Ala Asp Arg Arg Arg Gln Pro Leu 
            420                 425                 430         


Pro Thr Ala Ala Gly Glu Glu Met Thr Pro Pro Ala Gly Leu Ala Glu 
        435                 440                 445             


Glu Leu Pro Pro Gln Pro Gln Leu Gln Gln Gln Gly Arg Phe Leu Ala 
    450                 455                 460                 


Gly Val Ala Trp Asp Gly Ala Ala Arg Glu Leu Val Gly Asn Arg Ser 
465                 470                 475                 480 


Ala Leu Arg Leu Ser Arg Arg Gly Pro Gly Leu Gln Gln Pro Ser Pro 
                485                 490                 495     


Ser Val Ala Ala Ala Ala Gly Pro Ala Pro Gln Ser Leu Asp Leu His 
            500                 505                 510         


Lys Lys Pro Gln Arg Gly Arg Pro Thr Arg Ala Asp Pro Ala Leu Ala 
        515                 520                 525             


Glu Pro Thr Pro Thr Ala Ser Pro Gly Ser Ala Pro Ser Pro Ala Gly 
    530                 535                 540                 


Asp Pro Trp Gln Arg Ala Thr Lys His Arg Leu Gly Thr Glu His Gln 
545                 550                 555                 560 


Glu Arg Ala Ala Gln Ser Asp Gly Gly Ala Gly Leu Pro Pro Leu Val 
                565                 570                 575     


Ser Asp Pro Cys Asp Phe Asn Lys Phe Ile Leu Cys Asn Leu Thr Val 
            580                 585                 590         


Glu Ala Val Gly Ala Asp Ser Ala Ser Val Arg Trp Ala Val Arg Glu 
        595                 600                 605             


His Arg Ser Pro Arg Pro Leu Gly Gly Ala Arg Phe Arg Leu Leu Phe 
    610                 615                 620                 


Asp Arg Phe Gly Gln Gln Pro Lys Phe His Arg Phe Val Tyr Leu Pro 
625                 630                 635                 640 


Glu Ser Ser Asp Ser Ala Thr Leu Arg Glu Leu Arg Gly Asp Thr Pro 
                645                 650                 655     


Tyr Leu Val Cys Val Glu Gly Val Leu Gly Gly Arg Val Cys Pro Val 
            660                 665                 670         


Ala Pro Arg Asp His Cys Ala Gly Leu Val Thr Leu Pro Glu Ala Gly 
        675                 680                 685             


Ser Arg Gly Gly Val Asp Tyr Gln Leu Leu Thr Leu Ala Leu Leu Thr 
    690                 695                 700                 


Val Asn Ala Leu Leu Val Leu Leu Ala Leu Ala Ala Trp Ala Ser Arg 
705                 710                 715                 720 


Trp Leu Arg Arg Lys Leu Arg Ala Arg Arg Lys Gly Gly Ala Pro Val 
                725                 730                 735     


His Val Arg His Met Tyr Ser Thr Arg Arg Pro Leu Arg Ser Met Gly 
            740                 745                 750         


Thr Gly Val Ser Ala Asp Phe Ser Gly Phe Gln Ser His Arg Pro Arg 
        755                 760                 765             


Thr Thr Val Cys Ala Leu Ser Glu Ala Asp Leu Ile Glu Phe Pro Cys 
    770                 775                 780                 


Asp Arg Phe Met Asp Ser Ala Gly Gly Gly Ala Gly Gly Ser Leu Arg 
785                 790                 795                 800 


Arg Glu Asp Arg Leu Leu Gln Arg Phe Ala Asp 
                805                 810     


<210>  3646
<211>  632
<212>  PRT
<213>  homo sapiens

<400>  3646

Met Asp Thr Met Met Leu Asn Val Arg Asn Leu Phe Glu Gln Leu Val 
1               5                   10                  15      


Arg Arg Val Glu Ile Leu Ser Glu Gly Asn Glu Val Gln Phe Ile Gln 
            20                  25                  30          


Leu Ala Lys Asp Phe Glu Asp Phe Arg Lys Lys Trp Gln Arg Thr Asp 
        35                  40                  45              


His Glu Leu Gly Lys Tyr Lys Asp Leu Leu Met Lys Ala Glu Thr Glu 
    50                  55                  60                  


Arg Ser Ala Leu Asp Val Lys Leu Lys His Ala Arg Asn Gln Val Asp 
65                  70                  75                  80  


Val Glu Ile Lys Arg Arg Gln Arg Ala Glu Ala Asp Cys Glu Lys Leu 
                85                  90                  95      


Glu Arg Gln Ile Gln Leu Ile Arg Glu Met Leu Met Cys Asp Thr Ser 
            100                 105                 110         


Gly Ser Ile Gln Leu Ser Glu Glu Gln Lys Ser Ala Leu Ala Phe Leu 
        115                 120                 125             


Asn Arg Gly Gln Pro Ser Ser Ser Asn Ala Gly Asn Lys Arg Leu Ser 
    130                 135                 140                 


Thr Ile Asp Glu Ser Gly Ser Ile Leu Ser Asp Ile Ser Phe Asp Lys 
145                 150                 155                 160 


Thr Asp Glu Ser Leu Asp Trp Asp Ser Ser Leu Val Lys Thr Phe Lys 
                165                 170                 175     


Leu Lys Lys Arg Glu Lys Arg Arg Ser Thr Ser Arg Gln Phe Val Asp 
            180                 185                 190         


Gly Pro Pro Gly Pro Val Lys Lys Thr Arg Ser Ile Gly Ser Ala Val 
        195                 200                 205             


Asp Gln Gly Asn Glu Ser Ile Val Ala Lys Thr Thr Val Thr Val Pro 
    210                 215                 220                 


Asn Asp Gly Gly Pro Ile Glu Ala Val Ser Thr Ile Glu Thr Val Pro 
225                 230                 235                 240 


Tyr Trp Thr Arg Ser Arg Arg Lys Thr Gly Thr Leu Gln Pro Trp Asn 
                245                 250                 255     


Ser Asp Ser Thr Leu Asn Ser Arg Gln Leu Glu Pro Arg Thr Glu Thr 
            260                 265                 270         


Asp Ser Val Gly Thr Pro Gln Ser Asn Gly Gly Met Arg Leu His Asp 
        275                 280                 285             


Phe Val Ser Lys Thr Val Ile Lys Pro Glu Ser Cys Val Pro Cys Gly 
    290                 295                 300                 


Lys Arg Ile Lys Phe Gly Lys Leu Ser Leu Lys Cys Arg Asp Cys Arg 
305                 310                 315                 320 


Val Val Ser His Pro Glu Cys Arg Asp Arg Cys Pro Leu Pro Cys Ile 
                325                 330                 335     


Pro Thr Leu Ile Gly Thr Pro Val Lys Ile Gly Glu Gly Met Leu Ala 
            340                 345                 350         


Asp Phe Val Ser Gln Thr Ser Pro Met Ile Pro Ser Ile Val Val His 
        355                 360                 365             


Cys Val Asn Glu Ile Glu Gln Arg Gly Leu Thr Glu Thr Gly Leu Tyr 
    370                 375                 380                 


Arg Ile Ser Gly Cys Asp Arg Thr Val Lys Glu Leu Lys Glu Lys Phe 
385                 390                 395                 400 


Leu Arg Val Lys Thr Val Pro Leu Leu Ser Lys Val Asp Asp Ile His 
                405                 410                 415     


Ala Ile Cys Ser Leu Leu Lys Asp Phe Leu Arg Asn Leu Lys Glu Pro 
            420                 425                 430         


Leu Leu Thr Phe Arg Leu Asn Arg Ala Phe Met Glu Ala Ala Glu Ile 
        435                 440                 445             


Thr Asp Glu Asp Asn Ser Ile Ala Ala Met Tyr Gln Ala Val Gly Glu 
    450                 455                 460                 


Leu Pro Gln Ala Asn Arg Asp Thr Leu Ala Phe Leu Met Ile His Leu 
465                 470                 475                 480 


Gln Arg Val Ala Gln Ser Pro His Thr Lys Met Asp Val Ala Asn Leu 
                485                 490                 495     


Ala Lys Val Phe Gly Pro Thr Ile Val Ala His Ala Val Pro Asn Pro 
            500                 505                 510         


Asp Pro Val Thr Met Leu Gln Asp Ile Lys Arg Gln Pro Lys Val Val 
        515                 520                 525             


Glu Arg Leu Leu Ser Leu Pro Leu Glu Tyr Trp Ser Gln Phe Met Met 
    530                 535                 540                 


Val Glu Gln Glu Asn Ile Asp Pro Leu His Val Ile Glu Asn Ser Asn 
545                 550                 555                 560 


Ala Phe Ser Thr Pro Gln Thr Pro Asp Ile Lys Val Ser Leu Leu Gly 
                565                 570                 575     


Pro Val Thr Thr Pro Glu His Gln Leu Leu Lys Thr Pro Ser Ser Ser 
            580                 585                 590         


Ser Leu Ser Gln Arg Val Arg Ser Thr Leu Thr Lys Asn Thr Pro Arg 
        595                 600                 605             


Phe Gly Ser Lys Ser Lys Ser Ala Thr Asn Leu Gly Arg Gln Gly Asn 
    610                 615                 620                 


Phe Phe Ala Ser Pro Met Leu Lys 
625                 630         


<210>  3647
<211>  386
<212>  PRT
<213>  homo sapiens

<400>  3647

Met Gly Leu Trp Gly Gln Ser Val Pro Thr Ala Ser Ser Ala Arg Ala 
1               5                   10                  15      


Gly Arg Tyr Pro Gly Ala Arg Thr Ala Ser Gly Thr Arg Pro Trp Leu 
            20                  25                  30          


Leu Asp Pro Lys Ile Leu Lys Phe Val Val Phe Ile Val Ala Val Leu 
        35                  40                  45              


Leu Pro Val Arg Val Asp Ser Ala Thr Ile Pro Arg Gln Asp Glu Val 
    50                  55                  60                  


Pro Gln Gln Thr Val Ala Pro Gln Gln Gln Arg Arg Ser Leu Lys Glu 
65                  70                  75                  80  


Glu Glu Cys Pro Ala Gly Ser His Arg Ser Glu Tyr Thr Gly Ala Cys 
                85                  90                  95      


Asn Pro Cys Thr Glu Gly Val Asp Tyr Thr Ile Ala Ser Asn Asn Leu 
            100                 105                 110         


Pro Ser Cys Leu Leu Cys Thr Val Cys Lys Ser Gly Gln Thr Asn Lys 
        115                 120                 125             


Ser Ser Cys Thr Thr Thr Arg Asp Thr Val Cys Gln Cys Glu Lys Gly 
    130                 135                 140                 


Ser Phe Gln Asp Lys Asn Ser Pro Glu Met Cys Arg Thr Cys Arg Thr 
145                 150                 155                 160 


Gly Cys Pro Arg Gly Met Val Lys Val Ser Asn Cys Thr Pro Arg Ser 
                165                 170                 175     


Asp Ile Lys Cys Lys Asn Glu Ser Ala Ala Ser Ser Thr Gly Lys Thr 
            180                 185                 190         


Pro Ala Ala Glu Glu Thr Val Thr Thr Ile Leu Gly Met Leu Ala Ser 
        195                 200                 205             


Pro Tyr His Tyr Leu Ile Ile Ile Val Val Leu Val Ile Ile Leu Ala 
    210                 215                 220                 


Val Val Val Val Gly Phe Ser Cys Arg Lys Lys Phe Ile Ser Tyr Leu 
225                 230                 235                 240 


Lys Gly Ile Cys Ser Gly Gly Gly Gly Gly Pro Glu Arg Val His Arg 
                245                 250                 255     


Val Leu Phe Arg Arg Arg Ser Cys Pro Ser Arg Val Pro Gly Ala Glu 
            260                 265                 270         


Asp Asn Ala Arg Asn Glu Thr Leu Ser Asn Arg Tyr Leu Gln Pro Thr 
        275                 280                 285             


Gln Val Ser Glu Gln Glu Ile Gln Gly Gln Glu Leu Ala Glu Leu Thr 
    290                 295                 300                 


Gly Val Thr Val Glu Leu Pro Glu Glu Pro Gln Arg Leu Leu Glu Gln 
305                 310                 315                 320 


Ala Glu Ala Glu Gly Cys Gln Arg Arg Arg Leu Leu Val Pro Val Asn 
                325                 330                 335     


Asp Ala Asp Ser Ala Asp Ile Ser Thr Leu Leu Asp Ala Ser Ala Thr 
            340                 345                 350         


Leu Glu Glu Gly His Ala Lys Glu Thr Ile Gln Asp Gln Leu Val Gly 
        355                 360                 365             


Ser Glu Lys Leu Phe Tyr Glu Glu Asp Glu Ala Gly Ser Ala Thr Ser 
    370                 375                 380                 


Cys Leu 
385     


<210>  3648
<211>  339
<212>  PRT
<213>  homo sapiens

<400>  3648

Met Ala His Ser Pro Val Ala Val Gln Val Pro Gly Met Gln Gly Ser 
1               5                   10                  15      


Lys Leu Trp Ile Ile Met Glu Tyr Leu Gly Gly Gly Ser Ala Leu Asp 
            20                  25                  30          


Leu Leu Arg Ala Gly Pro Phe Asp Glu Phe Gln Ile Ala Thr Met Leu 
        35                  40                  45              


Lys Glu Ile Leu Lys Gly Leu Asp Tyr Leu His Ser Glu Lys Lys Ile 
    50                  55                  60                  


His Arg Asp Ile Lys Ala Ala Asn Val Leu Leu Ser Glu Gln Gly Asp 
65                  70                  75                  80  


Val Lys Leu Ala Asp Phe Gly Val Ala Gly Gln Leu Thr Asp Thr Gln 
                85                  90                  95      


Ile Lys Arg Asn Thr Phe Val Gly Thr Pro Phe Trp Met Ala Pro Glu 
            100                 105                 110         


Val Ile Gln Gln Ser Ala Tyr Asp Ser Lys Ala Asp Ile Trp Ser Leu 
        115                 120                 125             


Gly Ile Thr Ala Ile Glu Leu Ala Lys Gly Glu Pro Pro Asn Ser Asp 
    130                 135                 140                 


Met His Pro Met Arg Val Leu Phe Leu Ile Pro Lys Asn Asn Pro Pro 
145                 150                 155                 160 


Thr Leu Val Gly Asp Phe Thr Lys Ser Phe Lys Glu Phe Ile Asp Ala 
                165                 170                 175     


Cys Leu Asn Lys Asp Pro Ser Phe Arg Pro Thr Ala Lys Glu Leu Leu 
            180                 185                 190         


Lys His Lys Phe Ile Val Lys Asn Ser Lys Lys Thr Ser Tyr Leu Thr 
        195                 200                 205             


Glu Leu Ile Asp Arg Phe Lys Arg Trp Lys Ala Glu Gly His Ser Asp 
    210                 215                 220                 


Asp Glu Ser Asp Ser Glu Gly Ser Asp Ser Glu Ser Thr Ser Arg Glu 
225                 230                 235                 240 


Asn Asn Thr His Pro Glu Trp Ser Phe Thr Thr Val Arg Lys Lys Pro 
                245                 250                 255     


Asp Pro Lys Lys Val Gln Asn Gly Ala Glu Gln Asp Leu Val Gln Thr 
            260                 265                 270         


Leu Ser Cys Leu Ser Met Ile Ile Thr Pro Ala Phe Ala Glu Leu Lys 
        275                 280                 285             


Gln Gln Asp Glu Asn Asn Ala Ser Arg Asn Gln Ala Ile Glu Glu Leu 
    290                 295                 300                 


Glu Lys Ser Ile Ala Val Ala Glu Ala Ala Cys Pro Gly Ile Thr Asp 
305                 310                 315                 320 


Lys Met Val Lys Lys Leu Ile Glu Lys Phe Gln Lys Cys Ser Ala Asp 
                325                 330                 335     


Glu Ser Pro 
            


<210>  3649
<211>  559
<212>  PRT
<213>  homo sapiens

<400>  3649

Met Pro Leu Val Lys Arg Asn Ile Asp Pro Arg His Leu Cys His Thr 
1               5                   10                  15      


Ala Leu Pro Arg Gly Ile Lys Asn Glu Leu Glu Cys Val Thr Asn Ile 
            20                  25                  30          


Ser Leu Ala Asn Ile Ile Arg Gln Leu Ser Ser Leu Ser Lys Tyr Ala 
        35                  40                  45              


Glu Asp Ile Phe Gly Glu Leu Phe Asn Glu Ala His Ser Phe Ser Phe 
    50                  55                  60                  


Arg Val Asn Ser Leu Gln Glu Arg Val Asp Arg Leu Ser Val Ser Val 
65                  70                  75                  80  


Thr Gln Leu Asp Pro Lys Glu Glu Glu Leu Ser Leu Gln Asp Ile Thr 
                85                  90                  95      


Met Arg Lys Ala Phe Arg Ser Ser Thr Ile Gln Asp Gln Gln Leu Phe 
            100                 105                 110         


Asp Arg Lys Thr Leu Pro Ile Pro Leu Gln Glu Thr Tyr Asp Val Cys 
        115                 120                 125             


Glu Gln Pro Pro Pro Leu Asn Ile Leu Thr Pro Tyr Arg Asp Asp Gly 
    130                 135                 140                 


Lys Glu Gly Leu Lys Phe Tyr Thr Asn Pro Ser Tyr Phe Phe Asp Leu 
145                 150                 155                 160 


Trp Lys Glu Lys Met Leu Gln Asp Thr Glu Asp Lys Arg Lys Glu Lys 
                165                 170                 175     


Arg Lys Gln Lys Gln Lys Asn Leu Asp Arg Pro His Glu Pro Glu Lys 
            180                 185                 190         


Val Pro Arg Ala Pro His Asp Arg Arg Arg Glu Trp Gln Lys Leu Ala 
        195                 200                 205             


Gln Gly Pro Glu Leu Ala Glu Asp Asp Ala Asn Leu Leu His Lys His 
    210                 215                 220                 


Ile Glu Val Ala Asn Gly Pro Ala Ser His Phe Glu Thr Arg Pro Gln 
225                 230                 235                 240 


Thr Tyr Val Asp His Met Asp Gly Ser Tyr Ser Leu Ser Ala Leu Pro 
                245                 250                 255     


Phe Ser Gln Met Ser Glu Leu Leu Thr Arg Ala Glu Glu Arg Val Leu 
            260                 265                 270         


Val Arg Pro His Glu Pro Pro Pro Pro Pro Pro Met His Gly Ala Gly 
        275                 280                 285             


Asp Ala Lys Pro Ile Pro Thr Cys Ile Ser Ser Ala Thr Gly Leu Ile 
    290                 295                 300                 


Glu Asn Arg Pro Gln Ser Pro Ala Thr Gly Arg Thr Pro Val Phe Val 
305                 310                 315                 320 


Ser Pro Thr Pro Pro Pro Pro Pro Pro Pro Leu Pro Ser Ala Leu Ser 
                325                 330                 335     


Thr Ser Ser Leu Arg Ala Ser Met Thr Ser Thr Pro Pro Pro Pro Val 
            340                 345                 350         


Pro Pro Pro Pro Pro Pro Pro Ala Thr Ala Leu Gln Ala Pro Ala Val 
        355                 360                 365             


Pro Pro Pro Pro Ala Pro Leu Gln Ile Ala Pro Gly Val Leu His Pro 
    370                 375                 380                 


Ala Pro Pro Pro Ile Ala Pro Pro Leu Val Gln Pro Ser Pro Pro Val 
385                 390                 395                 400 


Ala Arg Ala Ala Pro Val Cys Glu Thr Val Pro Val His Pro Leu Pro 
                405                 410                 415     


Gln Gly Glu Val Gln Gly Leu Pro Pro Pro Pro Pro Pro Pro Pro Leu 
            420                 425                 430         


Pro Pro Pro Gly Ile Arg Pro Ser Ser Pro Val Thr Val Thr Ala Leu 
        435                 440                 445             


Ala His Pro Pro Ser Gly Leu His Pro Thr Pro Ser Thr Ala Pro Gly 
    450                 455                 460                 


Pro His Val Pro Leu Met Pro Pro Ser Pro Pro Ser Gln Val Ile Pro 
465                 470                 475                 480 


Ala Ser Glu Pro Lys Arg His Pro Ser Thr Leu Pro Val Ile Ser Asp 
                485                 490                 495     


Ala Arg Ser Val Leu Leu Glu Ala Ile Arg Lys Gly Ile Gln Leu Arg 
            500                 505                 510         


Lys Val Glu Glu Gln Arg Glu Gln Glu Ala Lys His Glu Arg Ile Glu 
        515                 520                 525             


Asn Asp Val Ala Thr Ile Leu Ser Arg Arg Ile Ala Val Glu Tyr Ser 
    530                 535                 540                 


Asp Ser Glu Asp Asp Ser Glu Phe Asp Glu Val Asp Trp Leu Glu 
545                 550                 555                 


<210>  3650
<211>  559
<212>  PRT
<213>  homo sapiens

<400>  3650

Met Pro Leu Val Lys Arg Asn Ile Asp Pro Arg His Leu Cys His Thr 
1               5                   10                  15      


Ala Leu Pro Arg Gly Ile Lys Asn Glu Leu Glu Cys Val Thr Asn Ile 
            20                  25                  30          


Ser Leu Ala Asn Ile Ile Arg Gln Leu Ser Ser Leu Ser Lys Tyr Ala 
        35                  40                  45              


Glu Asp Ile Phe Gly Glu Leu Phe Asn Glu Ala His Ser Phe Ser Phe 
    50                  55                  60                  


Arg Val Asn Ser Leu Gln Glu Arg Val Asp Arg Leu Ser Val Ser Val 
65                  70                  75                  80  


Thr Gln Leu Asp Pro Lys Glu Glu Glu Leu Ser Leu Gln Asp Ile Thr 
                85                  90                  95      


Met Arg Lys Ala Phe Arg Ser Ser Thr Ile Gln Asp Gln Gln Leu Phe 
            100                 105                 110         


Asp Arg Lys Thr Leu Pro Ile Pro Leu Gln Glu Thr Tyr Asp Val Cys 
        115                 120                 125             


Glu Gln Pro Pro Pro Leu Asn Ile Leu Thr Pro Tyr Arg Asp Asp Gly 
    130                 135                 140                 


Lys Glu Gly Leu Lys Phe Tyr Thr Asn Pro Ser Tyr Phe Phe Asp Leu 
145                 150                 155                 160 


Trp Lys Glu Lys Met Leu Gln Asp Thr Glu Asp Lys Arg Lys Glu Lys 
                165                 170                 175     


Arg Lys Gln Lys Gln Lys Asn Leu Asp Arg Pro His Glu Pro Glu Lys 
            180                 185                 190         


Val Pro Arg Ala Pro His Asp Arg Arg Arg Glu Trp Gln Lys Leu Ala 
        195                 200                 205             


Gln Gly Pro Glu Leu Ala Glu Asp Asp Ala Asn Leu Leu His Lys His 
    210                 215                 220                 


Ile Glu Val Ala Asn Gly Pro Ala Ser His Phe Glu Thr Arg Pro Gln 
225                 230                 235                 240 


Thr Tyr Val Asp His Met Asp Gly Ser Tyr Ser Leu Ser Ala Leu Pro 
                245                 250                 255     


Phe Ser Gln Met Ser Glu Leu Leu Thr Arg Ala Glu Glu Arg Val Leu 
            260                 265                 270         


Val Arg Pro His Glu Pro Pro Pro Pro Pro Pro Met His Gly Ala Gly 
        275                 280                 285             


Asp Ala Lys Pro Ile Pro Thr Cys Ile Ser Ser Ala Thr Gly Leu Ile 
    290                 295                 300                 


Glu Asn Arg Pro Gln Ser Pro Ala Thr Gly Arg Thr Pro Val Phe Val 
305                 310                 315                 320 


Ser Pro Thr Pro Pro Pro Pro Pro Pro Pro Leu Pro Ser Ala Leu Ser 
                325                 330                 335     


Thr Ser Ser Leu Arg Ala Ser Met Thr Ser Thr Pro Pro Pro Pro Val 
            340                 345                 350         


Pro Pro Pro Pro Pro Pro Pro Ala Thr Ala Leu Gln Ala Pro Ala Val 
        355                 360                 365             


Pro Pro Pro Pro Ala Pro Leu Gln Ile Ala Pro Gly Val Leu His Pro 
    370                 375                 380                 


Ala Pro Pro Pro Ile Ala Pro Pro Leu Val Gln Pro Ser Pro Pro Val 
385                 390                 395                 400 


Ala Arg Ala Ala Pro Val Cys Glu Thr Val Pro Val His Pro Leu Pro 
                405                 410                 415     


Gln Gly Glu Val Gln Gly Leu Pro Pro Pro Pro Pro Pro Pro Pro Leu 
            420                 425                 430         


Pro Pro Pro Gly Ile Arg Pro Ser Ser Pro Val Thr Val Thr Ala Leu 
        435                 440                 445             


Ala His Pro Pro Ser Gly Leu His Pro Thr Pro Ser Thr Ala Pro Gly 
    450                 455                 460                 


Pro His Val Pro Leu Met Pro Pro Ser Pro Pro Ser Gln Val Ile Pro 
465                 470                 475                 480 


Ala Ser Glu Pro Lys Arg His Pro Ser Thr Leu Pro Val Ile Ser Asp 
                485                 490                 495     


Ala Arg Ser Val Leu Leu Glu Ala Ile Arg Lys Gly Ile Gln Leu Arg 
            500                 505                 510         


Lys Val Glu Glu Gln Arg Glu Gln Glu Ala Lys His Glu Arg Ile Glu 
        515                 520                 525             


Asn Asp Val Ala Thr Ile Leu Ser Arg Arg Ile Ala Val Glu Tyr Ser 
    530                 535                 540                 


Asp Ser Glu Asp Asp Ser Glu Phe Asp Glu Val Asp Trp Leu Glu 
545                 550                 555                 


<210>  3651
<211>  551
<212>  PRT
<213>  homo sapiens

<400>  3651

Met Phe Gly Ile Gln Glu Asn Ile Pro Arg Gly Gly Thr Thr Met Lys 
1               5                   10                  15      


Glu Glu Pro Leu Gly Ser Gly Met Asn Pro Val Arg Ser Trp Met His 
            20                  25                  30          


Thr Ala Gly Val Val Asp Ala Asn Thr Ala Ala Gln Ser Gly Val Gly 
        35                  40                  45              


Leu Ala Arg Ala His Phe Glu Lys Gln Pro Pro Ser Asn Leu Arg Lys 
    50                  55                  60                  


Ser Asn Phe Phe His Phe Val Leu Ala Leu Tyr Asp Arg Gln Gly Gln 
65                  70                  75                  80  


Pro Val Glu Ile Glu Arg Thr Ala Phe Val Asp Phe Val Glu Lys Glu 
                85                  90                  95      


Lys Glu Pro Asn Asn Glu Lys Thr Asn Asn Gly Ile His Tyr Lys Leu 
            100                 105                 110         


Gln Leu Leu Tyr Ser Asn Gly Val Arg Thr Glu Gln Asp Leu Tyr Val 
        115                 120                 125             


Arg Leu Ile Asp Ser Met Thr Lys Gln Ala Ile Val Tyr Glu Gly Gln 
    130                 135                 140                 


Asp Lys Asn Pro Glu Met Cys Arg Val Leu Leu Thr His Glu Ile Met 
145                 150                 155                 160 


Cys Ser Arg Cys Cys Asp Lys Lys Ser Cys Gly Asn Arg Asn Glu Thr 
                165                 170                 175     


Pro Ser Asp Pro Val Ile Ile Asp Arg Phe Phe Leu Lys Phe Phe Leu 
            180                 185                 190         


Lys Cys Asn Gln Asn Cys Leu Lys Asn Ala Gly Asn Pro Arg Asp Met 
        195                 200                 205             


Arg Arg Phe Gln Val Val Val Ser Thr Thr Val Asn Val Asp Gly His 
    210                 215                 220                 


Val Leu Ala Val Ser Asp Asn Met Phe Val His Asn Asn Ser Lys His 
225                 230                 235                 240 


Gly Arg Arg Ala Arg Arg Leu Asp Pro Ser Glu Ala Thr Pro Cys Ile 
                245                 250                 255     


Lys Ala Ile Ser Pro Ser Glu Gly Trp Thr Thr Gly Gly Ala Thr Val 
            260                 265                 270         


Ile Ile Ile Gly Asp Asn Phe Phe Asp Gly Leu Gln Val Val Phe Gly 
        275                 280                 285             


Thr Met Leu Val Trp Ser Glu Leu Ile Thr Pro His Ala Ile Arg Val 
    290                 295                 300                 


Gln Thr Pro Pro Arg His Ile Pro Gly Val Val Glu Val Thr Leu Ser 
305                 310                 315                 320 


Tyr Lys Ser Lys Gln Phe Cys Lys Gly Ala Pro Gly Arg Phe Val Tyr 
                325                 330                 335     


Thr Ala Leu Asn Glu Pro Thr Ile Asp Tyr Gly Phe Gln Arg Leu Gln 
            340                 345                 350         


Lys Val Ile Pro Arg His Pro Gly Asp Pro Glu Arg Leu Pro Lys Glu 
        355                 360                 365             


Val Leu Leu Lys Arg Ala Ala Asp Leu Val Glu Ala Leu Tyr Gly Met 
    370                 375                 380                 


Pro His Asn Asn Gln Glu Ile Ile Leu Lys Arg Ala Ala Asp Ile Ala 
385                 390                 395                 400 


Glu Ala Leu Tyr Ser Val Pro Arg Asn His Asn Gln Ile Pro Thr Leu 
                405                 410                 415     


Gly Asn Asn Pro Ala His Thr Gly Met Met Gly Val Asn Ser Phe Ser 
            420                 425                 430         


Ser Gln Leu Ala Val Asn Val Ser Glu Thr Ser Gln Ala Asn Asp Gln 
        435                 440                 445             


Val Gly Tyr Ser Arg Asn Thr Ser Ser Val Ser Pro Arg Gly Tyr Val 
    450                 455                 460                 


Pro Ser Ser Thr Pro Gln Gln Ser Asn Tyr Asn Thr Val Ser Thr Ser 
465                 470                 475                 480 


Met Asn Gly Tyr Gly Ser Gly Ala Met Ala Ser Leu Gly Val Pro Gly 
                485                 490                 495     


Ser Pro Gly Phe Leu Asn Gly Ser Ser Ala Asn Ser Pro Tyr Gly Met 
            500                 505                 510         


Lys Gln Lys Ser Ala Phe Ala Pro Val Val Arg Pro Gln Ala Ser Pro 
        515                 520                 525             


Pro Pro Ser Cys Thr Ser Ala Asn Gly Asn Gly Leu Gln Ala Met Ser 
    530                 535                 540                 


Gly Leu Val Val Pro Pro Met 
545                 550     


<210>  3652
<211>  423
<212>  PRT
<213>  homo sapiens

<400>  3652

Met Glu Asn Lys Lys Lys Asp Lys Asp Lys Ser Asp Asp Arg Met Ala 
1               5                   10                  15      


Arg Pro Ser Gly Arg Ser Gly His Asn Thr Arg Gly Thr Gly Ser Ser 
            20                  25                  30          


Ser Ser Gly Val Leu Met Val Gly Pro Asn Phe Arg Val Gly Lys Lys 
        35                  40                  45              


Ile Gly Cys Gly Asn Phe Gly Glu Leu Arg Leu Gly Lys Asn Leu Tyr 
    50                  55                  60                  


Thr Asn Glu Tyr Val Ala Ile Lys Leu Glu Pro Met Lys Ser Arg Ala 
65                  70                  75                  80  


Pro Gln Leu His Leu Glu Tyr Arg Phe Tyr Lys Gln Leu Gly Ser Gly 
                85                  90                  95      


Asp Gly Ile Pro Gln Val Tyr Tyr Phe Gly Pro Cys Gly Lys Tyr Asn 
            100                 105                 110         


Ala Met Val Leu Glu Leu Leu Gly Pro Ser Leu Glu Asp Leu Phe Asp 
        115                 120                 125             


Leu Cys Asp Arg Thr Phe Ser Leu Lys Thr Val Leu Met Ile Ala Ile 
    130                 135                 140                 


Gln Leu Ile Ser Arg Met Glu Tyr Val His Ser Lys Asn Leu Ile Tyr 
145                 150                 155                 160 


Arg Asp Val Lys Pro Glu Asn Phe Leu Ile Gly Arg Pro Gly Asn Lys 
                165                 170                 175     


Thr Gln Gln Val Ile His Ile Ile Asp Phe Gly Leu Ala Lys Glu Tyr 
            180                 185                 190         


Ile Asp Pro Glu Thr Lys Lys His Ile Pro Tyr Arg Glu His Lys Ser 
        195                 200                 205             


Leu Thr Gly Thr Ala Arg Tyr Met Ser Ile Asn Thr His Leu Gly Lys 
    210                 215                 220                 


Glu Gln Ser Arg Arg Asp Asp Leu Glu Ala Leu Gly His Met Phe Met 
225                 230                 235                 240 


Tyr Phe Leu Arg Gly Ser Leu Pro Trp Gln Gly Leu Lys Ala Asp Thr 
                245                 250                 255     


Leu Lys Glu Arg Tyr Gln Lys Ile Gly Asp Thr Lys Arg Ala Thr Pro 
            260                 265                 270         


Ile Glu Val Leu Cys Glu Asn Phe Pro Glu Met Ala Thr Tyr Leu Arg 
        275                 280                 285             


Tyr Val Arg Arg Leu Asp Phe Phe Glu Lys Pro Asp Tyr Asp Tyr Leu 
    290                 295                 300                 


Arg Lys Leu Phe Thr Asp Leu Phe Asp Arg Lys Gly Tyr Met Phe Asp 
305                 310                 315                 320 


Tyr Glu Tyr Asp Trp Ile Gly Lys Gln Leu Pro Thr Pro Val Gly Ala 
                325                 330                 335     


Val Gln Gln Asp Pro Ala Leu Ser Ser Asn Arg Glu Ala His Gln His 
            340                 345                 350         


Arg Asp Lys Met Gln Gln Ser Lys Asn Gln Val Val Ser Ser Thr Asn 
        355                 360                 365             


Gly Glu Leu Asn Thr Asp Asp Pro Thr Ala Gly Arg Ser Asn Ala Pro 
    370                 375                 380                 


Ile Thr Ala Pro Thr Glu Val Glu Val Met Asp Glu Thr Asn Cys Gln 
385                 390                 395                 400 


Lys Val Leu Asn Met Trp Cys Cys Cys Phe Phe Lys Arg Arg Lys Arg 
                405                 410                 415     


Lys Thr Ile Gln Arg His Lys 
            420             


<210>  3653
<211>  775
<212>  PRT
<213>  homo sapiens

<400>  3653

Met Met Val Gln Arg Leu Gly Leu Ile Ser Pro Pro Ala Ser Gln Val 
1               5                   10                  15      


Ser Thr Ala Cys Asn Gln Ile Ser Pro Ser Leu Gln Arg Ala Met Asn 
            20                  25                  30          


Ala Ala Asn Leu Asn Ile Pro Pro Ser Asp Thr Arg Ser Leu Ile Ser 
        35                  40                  45              


Arg Glu Ser Leu Ala Ser Thr Thr Leu Ser Leu Thr Glu Ser Gln Ser 
    50                  55                  60                  


Ala Ser Ser Met Lys Gln Glu Trp Ser Gln Gly Tyr Arg Ala Leu Pro 
65                  70                  75                  80  


Ser Leu Ser Asn His Gly Ser Gln Asn Gly Leu Asp Leu Gly Asp Leu 
                85                  90                  95      


Leu Ser Leu Pro Pro Gly Thr Ser Met Ser Ser Asn Ser Val Ser Asn 
            100                 105                 110         


Ser Leu Pro Ser Tyr Leu Phe Gly Thr Glu Ser Ser His Ser Pro Tyr 
        115                 120                 125             


Pro Ser Pro Arg His Ser Ser Thr Arg Ser His Ser Ala Arg Ser Lys 
    130                 135                 140                 


Lys Arg Ala Leu Ser Leu Ser Pro Leu Ser Asp Gly Ile Gly Ile Asp 
145                 150                 155                 160 


Phe Asn Thr Ile Ile Arg Thr Ser Pro Thr Ser Leu Val Ala Tyr Ile 
                165                 170                 175     


Asn Gly Ser Arg Ala Ser Pro Ala Asn Leu Ser Pro Gln Pro Glu Val 
            180                 185                 190         


Tyr Gly His Phe Leu Gly Val Arg Gly Ser Cys Ile Pro Gln Pro Arg 
        195                 200                 205             


Pro Val Pro Gly Ser Gln Lys Gly Val Leu Val Ala Pro Gly Gly Leu 
    210                 215                 220                 


Ala Leu Pro Ala Tyr Gly Glu Asp Gly Ala Leu Glu His Glu Arg Met 
225                 230                 235                 240 


Gln Gln Leu Glu His Gly Gly Leu Gln Pro Gly Leu Val Asn His Met 
                245                 250                 255     


Val Val Gln His Gly Leu Pro Gly Pro Asp Ser Gln Ser Ala Gly Leu 
            260                 265                 270         


Phe Lys Thr Glu Arg Leu Glu Glu Phe Pro Gly Ser Thr Val Asp Leu 
        275                 280                 285             


Pro Pro Ala Pro Pro Leu Pro Pro Leu Pro Pro Pro Pro Gly Pro Pro 
    290                 295                 300                 


Pro Pro Tyr His Ala His Ala His Leu His His Pro Glu Leu Gly Pro 
305                 310                 315                 320 


His Ala Gln Gln Leu Ala Leu Pro Gln Ala Thr Leu Asp Asp Asp Gly 
                325                 330                 335     


Glu Met Asp Gly Ile Gly Gly Lys His Cys Cys Arg Trp Ile Asp Cys 
            340                 345                 350         


Ser Ala Leu Tyr Asp Gln Gln Glu Glu Leu Val Arg His Ile Glu Lys 
        355                 360                 365             


Val His Ile Asp Gln Arg Lys Gly Glu Asp Phe Thr Cys Phe Trp Ala 
    370                 375                 380                 


Gly Cys Pro Arg Arg Tyr Lys Pro Phe Asn Ala Arg Tyr Lys Leu Leu 
385                 390                 395                 400 


Ile His Met Arg Val His Ser Gly Glu Lys Pro Asn Lys Cys Thr Phe 
                405                 410                 415     


Glu Gly Cys Glu Lys Ala Phe Ser Arg Leu Glu Asn Leu Lys Ile His 
            420                 425                 430         


Leu Arg Ser His Thr Gly Glu Lys Pro Tyr Leu Cys Gln His Pro Gly 
        435                 440                 445             


Cys Gln Lys Ala Phe Ser Asn Ser Ser Asp Arg Ala Lys His Gln Arg 
    450                 455                 460                 


Thr His Leu Asp Thr Lys Pro Tyr Ala Cys Gln Ile Pro Gly Cys Thr 
465                 470                 475                 480 


Lys Arg Tyr Thr Asp Pro Ser Ser Leu Arg Lys His Val Lys Ala His 
                485                 490                 495     


Ser Ser Lys Glu Gln Gln Ala Arg Lys Lys Leu Arg Ser Ser Thr Glu 
            500                 505                 510         


Leu His Pro Asp Leu Leu Thr Asp Cys Leu Thr Val Gln Ser Leu Gln 
        515                 520                 525             


Pro Ala Thr Ser Pro Arg Asp Ala Ala Ala Glu Gly Thr Val Gly Arg 
    530                 535                 540                 


Ser Pro Gly Pro Gly Pro Asp Leu Tyr Ser Ala Pro Ile Phe Ser Ser 
545                 550                 555                 560 


Asn Tyr Ser Ser Arg Ser Gly Thr Ala Ala Gly Ala Val Pro Pro Pro 
                565                 570                 575     


His Pro Val Ser His Pro Ser Pro Gly His Asn Val Gln Gly Ser Pro 
            580                 585                 590         


His Asn Pro Ser Ser Gln Leu Pro Pro Leu Thr Ala Val Asp Ala Gly 
        595                 600                 605             


Ala Glu Arg Phe Ala Pro Ser Ala Pro Ser Pro His His Ile Ser Pro 
    610                 615                 620                 


Arg Arg Val Pro Ala Pro Ser Ser Ile Leu Gln Arg Thr Gln Pro Pro 
625                 630                 635                 640 


Tyr Thr Gln Gln Pro Ser Gly Ser His Leu Lys Ser Tyr Gln Pro Glu 
                645                 650                 655     


Thr Asn Ser Ser Phe Gln Pro Asn Gly Ile His Val His Gly Phe Tyr 
            660                 665                 670         


Gly Gln Leu Gln Lys Phe Cys Pro Pro His Tyr Pro Asp Ser Gln Arg 
        675                 680                 685             


Ile Val Pro Pro Val Ser Ser Cys Ser Val Val Pro Ser Phe Glu Asp 
    690                 695                 700                 


Cys Leu Val Pro Thr Ser Met Gly Gln Ala Ser Phe Asp Val Phe His 
705                 710                 715                 720 


Arg Ala Phe Ser Thr His Ser Gly Ile Thr Val Tyr Asp Leu Pro Ser 
                725                 730                 735     


Ser Ser Ser Ser Leu Phe Gly Glu Ser Leu Arg Ser Gly Ala Glu Asp 
            740                 745                 750         


Ala Thr Phe Leu Gln Ile Ser Thr Val Asp Arg Cys Pro Ser Gln Leu 
        755                 760                 765             


Ser Ser Val Tyr Thr Glu Gly 
    770                 775 


<210>  3654
<211>  781
<212>  PRT
<213>  homo sapiens

<400>  3654

Met Ala Thr Gln Ala Asp Leu Met Glu Leu Asp Met Ala Met Glu Pro 
1               5                   10                  15      


Asp Arg Lys Ala Ala Val Ser His Trp Gln Gln Gln Ser Tyr Leu Asp 
            20                  25                  30          


Ser Gly Ile His Ser Gly Ala Thr Thr Thr Ala Pro Ser Leu Ser Gly 
        35                  40                  45              


Lys Gly Asn Pro Glu Glu Glu Asp Val Asp Thr Ser Gln Val Leu Tyr 
    50                  55                  60                  


Glu Trp Glu Gln Gly Phe Ser Gln Ser Phe Thr Gln Glu Gln Val Ala 
65                  70                  75                  80  


Asp Ile Asp Gly Gln Tyr Ala Met Thr Arg Ala Gln Arg Val Arg Ala 
                85                  90                  95      


Ala Met Phe Pro Glu Thr Leu Asp Glu Gly Met Gln Ile Pro Ser Thr 
            100                 105                 110         


Gln Phe Asp Ala Ala His Pro Thr Asn Val Gln Arg Leu Ala Glu Pro 
        115                 120                 125             


Ser Gln Met Leu Lys His Ala Val Val Asn Leu Ile Asn Tyr Gln Asp 
    130                 135                 140                 


Asp Ala Glu Leu Ala Thr Arg Ala Ile Pro Glu Leu Thr Lys Leu Leu 
145                 150                 155                 160 


Asn Asp Glu Asp Gln Val Val Val Asn Lys Ala Ala Val Met Val His 
                165                 170                 175     


Gln Leu Ser Lys Lys Glu Ala Ser Arg His Ala Ile Met Arg Ser Pro 
            180                 185                 190         


Gln Met Val Ser Ala Ile Val Arg Thr Met Gln Asn Thr Asn Asp Val 
        195                 200                 205             


Glu Thr Ala Arg Cys Thr Ala Gly Thr Leu His Asn Leu Ser His His 
    210                 215                 220                 


Arg Glu Gly Leu Leu Ala Ile Phe Lys Ser Gly Gly Ile Pro Ala Leu 
225                 230                 235                 240 


Val Lys Met Leu Gly Ser Pro Val Asp Ser Val Leu Phe Tyr Ala Ile 
                245                 250                 255     


Thr Thr Leu His Asn Leu Leu Leu His Gln Glu Gly Ala Lys Met Ala 
            260                 265                 270         


Val Arg Leu Ala Gly Gly Leu Gln Lys Met Val Ala Leu Leu Asn Lys 
        275                 280                 285             


Thr Asn Val Lys Phe Leu Ala Ile Thr Thr Asp Cys Leu Gln Ile Leu 
    290                 295                 300                 


Ala Tyr Gly Asn Gln Glu Ser Lys Leu Ile Ile Leu Ala Ser Gly Gly 
305                 310                 315                 320 


Pro Gln Ala Leu Val Asn Ile Met Arg Thr Tyr Thr Tyr Glu Lys Leu 
                325                 330                 335     


Leu Trp Thr Thr Ser Arg Val Leu Lys Val Leu Ser Val Cys Ser Ser 
            340                 345                 350         


Asn Lys Pro Ala Ile Val Glu Ala Gly Gly Met Gln Ala Leu Gly Leu 
        355                 360                 365             


His Leu Thr Asp Pro Ser Gln Arg Leu Val Gln Asn Cys Leu Trp Thr 
    370                 375                 380                 


Leu Arg Asn Leu Ser Asp Ala Ala Thr Lys Gln Glu Gly Met Glu Gly 
385                 390                 395                 400 


Leu Leu Gly Thr Leu Val Gln Leu Leu Gly Ser Asp Asp Ile Asn Val 
                405                 410                 415     


Val Thr Cys Ala Ala Gly Ile Leu Ser Asn Leu Thr Cys Asn Asn Tyr 
            420                 425                 430         


Lys Asn Lys Met Met Val Cys Gln Val Gly Gly Ile Glu Ala Leu Val 
        435                 440                 445             


Arg Thr Val Leu Arg Ala Gly Asp Arg Glu Asp Ile Thr Glu Pro Ala 
    450                 455                 460                 


Ile Cys Ala Leu Arg His Leu Thr Ser Arg His Gln Glu Ala Glu Met 
465                 470                 475                 480 


Ala Gln Asn Ala Val Arg Leu His Tyr Gly Leu Pro Val Val Val Lys 
                485                 490                 495     


Leu Leu His Pro Pro Ser His Trp Pro Leu Ile Lys Ala Thr Val Gly 
            500                 505                 510         


Leu Ile Arg Asn Leu Ala Leu Cys Pro Ala Asn His Ala Pro Leu Arg 
        515                 520                 525             


Glu Gln Gly Ala Ile Pro Arg Leu Val Gln Leu Leu Val Arg Ala His 
    530                 535                 540                 


Gln Asp Thr Gln Arg Arg Thr Ser Met Gly Gly Thr Gln Gln Gln Phe 
545                 550                 555                 560 


Val Glu Gly Val Arg Met Glu Glu Ile Val Glu Gly Cys Thr Gly Ala 
                565                 570                 575     


Leu His Ile Leu Ala Arg Asp Val His Asn Arg Ile Val Ile Arg Gly 
            580                 585                 590         


Leu Asn Thr Ile Pro Leu Phe Val Gln Leu Leu Tyr Ser Pro Ile Glu 
        595                 600                 605             


Asn Ile Gln Arg Val Ala Ala Gly Val Leu Cys Glu Leu Ala Gln Asp 
    610                 615                 620                 


Lys Glu Ala Ala Glu Ala Ile Glu Ala Glu Gly Ala Thr Ala Pro Leu 
625                 630                 635                 640 


Thr Glu Leu Leu His Ser Arg Asn Glu Gly Val Ala Thr Tyr Ala Ala 
                645                 650                 655     


Ala Val Leu Phe Arg Met Ser Glu Asp Lys Pro Gln Asp Tyr Lys Lys 
            660                 665                 670         


Arg Leu Ser Val Glu Leu Thr Ser Ser Leu Phe Arg Thr Glu Pro Met 
        675                 680                 685             


Ala Trp Asn Glu Thr Ala Asp Leu Gly Leu Asp Ile Gly Ala Gln Gly 
    690                 695                 700                 


Glu Pro Leu Gly Tyr Arg Gln Asp Asp Pro Ser Tyr Arg Ser Phe His 
705                 710                 715                 720 


Ser Gly Gly Tyr Gly Gln Asp Ala Leu Gly Met Asp Pro Met Met Glu 
                725                 730                 735     


His Glu Met Gly Gly His His Pro Gly Ala Asp Tyr Pro Val Asp Gly 
            740                 745                 750         


Leu Pro Asp Leu Gly His Ala Gln Asp Leu Met Asp Gly Leu Pro Pro 
        755                 760                 765             


Gly Asp Ser Asn Gln Leu Ala Trp Phe Asp Thr Asp Leu 
    770                 775                 780     


<210>  3655
<211>  651
<212>  PRT
<213>  homo sapiens

<400>  3655

Met Asn Gln Pro Gln Arg Met Ala Pro Val Gly Thr Asp Lys Glu Leu 
1               5                   10                  15      


Ser Asp Leu Leu Asp Phe Ser Met Met Phe Pro Leu Pro Val Thr Asn 
            20                  25                  30          


Gly Lys Gly Arg Pro Ala Ser Leu Ala Gly Ala Gln Phe Gly Gly Ser 
        35                  40                  45              


Gly Leu Glu Asp Arg Pro Ser Ser Gly Ser Trp Gly Ser Gly Asp Gln 
    50                  55                  60                  


Ser Ser Ser Ser Phe Asp Pro Ser Arg Thr Phe Ser Glu Gly Thr His 
65                  70                  75                  80  


Phe Thr Glu Ser His Ser Ser Leu Ser Ser Ser Thr Phe Leu Gly Pro 
                85                  90                  95      


Gly Leu Gly Gly Lys Ser Gly Glu Arg Gly Ala Tyr Ala Ser Phe Gly 
            100                 105                 110         


Arg Asp Ala Gly Val Gly Gly Leu Thr Gln Ala Gly Phe Leu Ser Gly 
        115                 120                 125             


Glu Leu Ala Leu Asn Ser Pro Gly Pro Leu Ser Pro Ser Gly Met Lys 
    130                 135                 140                 


Gly Thr Ser Gln Tyr Tyr Pro Ser Tyr Ser Gly Ser Ser Arg Arg Arg 
145                 150                 155                 160 


Ala Ala Asp Gly Ser Leu Asp Thr Gln Pro Lys Lys Val Arg Lys Val 
                165                 170                 175     


Pro Pro Gly Leu Pro Ser Ser Val Tyr Pro Pro Ser Ser Gly Glu Asp 
            180                 185                 190         


Tyr Gly Arg Asp Ala Thr Ala Tyr Pro Ser Ala Lys Thr Pro Ser Ser 
        195                 200                 205             


Thr Tyr Pro Ala Pro Phe Tyr Val Ala Asp Gly Ser Leu His Pro Ser 
    210                 215                 220                 


Ala Glu Leu Trp Ser Pro Pro Gly Gln Ala Gly Phe Gly Pro Met Leu 
225                 230                 235                 240 


Gly Gly Gly Ser Ser Pro Leu Pro Leu Pro Pro Gly Ser Gly Pro Val 
                245                 250                 255     


Gly Ser Ser Gly Ser Ser Ser Thr Phe Gly Gly Leu His Gln His Glu 
            260                 265                 270         


Arg Met Gly Tyr Gln Leu His Gly Ala Glu Val Asn Gly Gly Leu Pro 
        275                 280                 285             


Ser Ala Ser Ser Phe Ser Ser Ala Pro Gly Ala Thr Tyr Gly Gly Val 
    290                 295                 300                 


Ser Ser His Thr Pro Pro Val Ser Gly Ala Asp Ser Leu Leu Gly Ser 
305                 310                 315                 320 


Arg Gly Thr Thr Ala Gly Ser Ser Gly Asp Ala Leu Gly Lys Ala Leu 
                325                 330                 335     


Ala Ser Ile Tyr Ser Pro Asp His Ser Ser Asn Asn Phe Ser Ser Ser 
            340                 345                 350         


Pro Ser Thr Pro Val Gly Ser Pro Gln Gly Leu Ala Gly Thr Ser Gln 
        355                 360                 365             


Trp Pro Arg Ala Gly Ala Pro Gly Ala Leu Ser Pro Ser Tyr Asp Gly 
    370                 375                 380                 


Gly Leu His Gly Leu Gln Ser Lys Ile Glu Asp His Leu Asp Glu Ala 
385                 390                 395                 400 


Ile His Val Leu Arg Ser His Ala Val Gly Thr Ala Gly Asp Met His 
                405                 410                 415     


Thr Leu Leu Pro Gly His Gly Ala Leu Ala Ser Gly Phe Thr Gly Pro 
            420                 425                 430         


Met Ser Leu Gly Gly Arg His Ala Gly Leu Val Gly Gly Ser His Pro 
        435                 440                 445             


Glu Asp Gly Leu Ala Gly Ser Thr Ser Leu Met His Asn His Ala Ala 
    450                 455                 460                 


Leu Pro Ser Gln Pro Gly Thr Leu Pro Asp Leu Ser Arg Pro Pro Asp 
465                 470                 475                 480 


Ser Tyr Ser Gly Leu Gly Arg Ala Gly Ala Thr Ala Ala Ala Ser Glu 
                485                 490                 495     


Ile Lys Arg Glu Glu Lys Glu Asp Glu Glu Asn Thr Ser Ala Ala Asp 
            500                 505                 510         


His Ser Glu Glu Glu Lys Lys Glu Leu Lys Ala Pro Arg Ala Arg Thr 
        515                 520                 525             


Ser Ser Thr Asp Glu Val Leu Ser Leu Glu Glu Lys Asp Leu Arg Asp 
    530                 535                 540                 


Arg Glu Arg Arg Met Ala Asn Asn Ala Arg Glu Arg Val Arg Val Arg 
545                 550                 555                 560 


Asp Ile Asn Glu Ala Phe Arg Glu Leu Gly Arg Met Cys Gln Met His 
                565                 570                 575     


Leu Lys Ser Asp Lys Ala Gln Thr Lys Leu Leu Ile Leu Gln Gln Ala 
            580                 585                 590         


Val Gln Val Ile Leu Gly Leu Glu Gln Gln Val Arg Glu Arg Asn Leu 
        595                 600                 605             


Asn Pro Lys Ala Ala Cys Leu Lys Arg Arg Glu Glu Glu Lys Val Ser 
    610                 615                 620                 


Gly Val Val Gly Asp Pro Gln Met Val Leu Ser Ala Pro His Pro Gly 
625                 630                 635                 640 


Leu Ser Glu Ala His Asn Pro Ala Gly His Met 
                645                 650     


<210>  3656
<211>  667
<212>  PRT
<213>  homo sapiens

<400>  3656

Met His His Gln Gln Arg Met Ala Ala Leu Gly Thr Asp Lys Glu Leu 
1               5                   10                  15      


Ser Asp Leu Leu Asp Phe Ser Ala Met Phe Ser Pro Pro Val Ser Ser 
            20                  25                  30          


Gly Lys Asn Gly Pro Thr Ser Leu Ala Ser Gly His Phe Thr Gly Ser 
        35                  40                  45              


Asn Val Glu Asp Arg Ser Ser Ser Gly Ser Trp Gly Asn Gly Gly His 
    50                  55                  60                  


Pro Ser Pro Ser Arg Asn Tyr Gly Asp Gly Thr Pro Tyr Asp His Met 
65                  70                  75                  80  


Thr Ser Arg Asp Leu Gly Ser His Asp Asn Leu Ser Pro Pro Phe Val 
                85                  90                  95      


Asn Ser Arg Ile Gln Ser Lys Thr Glu Arg Gly Ser Tyr Ser Ser Tyr 
            100                 105                 110         


Gly Arg Glu Ser Asn Leu Gln Gly Cys His Gln Gln Ser Leu Leu Gly 
        115                 120                 125             


Gly Asp Met Asp Met Gly Asn Pro Gly Thr Leu Ser Pro Thr Lys Pro 
    130                 135                 140                 


Gly Ser Gln Tyr Tyr Gln Tyr Ser Ser Asn Asn Pro Arg Arg Arg Pro 
145                 150                 155                 160 


Leu His Ser Ser Ala Met Glu Val Gln Thr Lys Lys Val Arg Lys Val 
                165                 170                 175     


Pro Pro Gly Leu Pro Ser Ser Val Tyr Ala Pro Ser Ala Ser Thr Ala 
            180                 185                 190         


Asp Tyr Asn Arg Asp Ser Pro Gly Tyr Pro Ser Ser Lys Pro Ala Thr 
        195                 200                 205             


Ser Thr Phe Pro Ser Ser Phe Phe Met Gln Asp Gly His His Ser Ser 
    210                 215                 220                 


Asp Pro Trp Ser Ser Ser Ser Gly Met Asn Gln Pro Gly Tyr Ala Gly 
225                 230                 235                 240 


Met Leu Gly Asn Ser Ser His Ile Pro Gln Ser Ser Ser Tyr Cys Ser 
                245                 250                 255     


Leu His Pro His Glu Arg Leu Ser Tyr Pro Ser His Ser Ser Ala Asp 
            260                 265                 270         


Ile Asn Ser Ser Leu Pro Pro Met Ser Thr Phe His Arg Ser Gly Thr 
        275                 280                 285             


Asn His Tyr Ser Thr Ser Ser Cys Thr Pro Pro Ala Asn Gly Thr Asp 
    290                 295                 300                 


Ser Ile Met Ala Asn Arg Gly Ser Gly Ala Ala Gly Ser Ser Gln Thr 
305                 310                 315                 320 


Gly Asp Ala Leu Gly Lys Ala Leu Ala Ser Ile Tyr Ser Pro Asp His 
                325                 330                 335     


Thr Asn Asn Ser Phe Ser Ser Asn Pro Ser Thr Pro Val Gly Ser Pro 
            340                 345                 350         


Pro Ser Leu Ser Ala Gly Thr Ala Val Trp Ser Arg Asn Gly Gly Gln 
        355                 360                 365             


Ala Ser Ser Ser Pro Asn Tyr Glu Gly Pro Leu His Ser Leu Gln Ser 
    370                 375                 380                 


Arg Ile Glu Asp Arg Leu Glu Arg Leu Asp Asp Ala Ile His Val Leu 
385                 390                 395                 400 


Arg Asn His Ala Val Gly Pro Ser Thr Ala Met Pro Gly Gly His Gly 
                405                 410                 415     


Asp Met His Gly Ile Ile Gly Pro Ser His Asn Gly Ala Met Gly Gly 
            420                 425                 430         


Leu Gly Ser Gly Tyr Gly Thr Gly Leu Leu Ser Ala Asn Arg His Ser 
        435                 440                 445             


Leu Met Val Gly Thr His Arg Glu Asp Gly Val Ala Leu Arg Gly Ser 
    450                 455                 460                 


His Ser Leu Leu Pro Asn Gln Val Pro Val Pro Gln Leu Pro Val Gln 
465                 470                 475                 480 


Ser Ala Thr Ser Pro Asp Leu Asn Pro Pro Gln Asp Pro Tyr Arg Gly 
                485                 490                 495     


Met Pro Pro Gly Leu Gln Gly Gln Ser Val Ser Ser Gly Ser Ser Glu 
            500                 505                 510         


Ile Lys Ser Asp Asp Glu Gly Asp Glu Asn Leu Gln Asp Thr Lys Ser 
        515                 520                 525             


Ser Glu Asp Lys Lys Leu Asp Asp Asp Lys Lys Asp Ile Lys Ser Ile 
    530                 535                 540                 


Thr Ser Asn Asn Asp Asp Glu Asp Leu Thr Pro Glu Gln Lys Ala Glu 
545                 550                 555                 560 


Arg Glu Lys Glu Arg Arg Met Ala Asn Asn Ala Arg Glu Arg Leu Arg 
                565                 570                 575     


Val Arg Asp Ile Asn Glu Ala Phe Lys Glu Leu Gly Arg Met Val Gln 
            580                 585                 590         


Leu His Leu Lys Ser Asp Lys Pro Gln Thr Lys Leu Leu Ile Leu His 
        595                 600                 605             


Gln Ala Val Ala Val Ile Leu Ser Leu Glu Gln Gln Val Arg Glu Arg 
    610                 615                 620                 


Asn Leu Asn Pro Lys Ala Ala Cys Leu Lys Arg Arg Glu Glu Glu Lys 
625                 630                 635                 640 


Val Ser Ser Glu Pro Pro Pro Leu Ser Leu Ala Gly Pro His Pro Gly 
                645                 650                 655     


Met Gly Asp Ala Ser Asn His Met Gly Gln Met 
            660                 665         


<210>  3657
<211>  826
<212>  PRT
<213>  homo sapiens

<400>  3657

Met Glu Gly Ala Gly Gly Ala Asn Asp Lys Lys Lys Ile Ser Ser Glu 
1               5                   10                  15      


Arg Arg Lys Glu Lys Ser Arg Asp Ala Ala Arg Ser Arg Arg Ser Lys 
            20                  25                  30          


Glu Ser Glu Val Phe Tyr Glu Leu Ala His Gln Leu Pro Leu Pro His 
        35                  40                  45              


Asn Val Ser Ser His Leu Asp Lys Ala Ser Val Met Arg Leu Thr Ile 
    50                  55                  60                  


Ser Tyr Leu Arg Val Arg Lys Leu Leu Asp Ala Gly Asp Leu Asp Ile 
65                  70                  75                  80  


Glu Asp Asp Met Lys Ala Gln Met Asn Cys Phe Tyr Leu Lys Ala Leu 
                85                  90                  95      


Asp Gly Phe Val Met Val Leu Thr Asp Asp Gly Asp Met Ile Tyr Ile 
            100                 105                 110         


Ser Asp Asn Val Asn Lys Tyr Met Gly Leu Thr Gln Phe Glu Leu Thr 
        115                 120                 125             


Gly His Ser Val Phe Asp Phe Thr His Pro Cys Asp His Glu Glu Met 
    130                 135                 140                 


Arg Glu Met Leu Thr His Arg Asn Gly Leu Val Lys Lys Gly Lys Glu 
145                 150                 155                 160 


Gln Asn Thr Gln Arg Ser Phe Phe Leu Arg Met Lys Cys Thr Leu Thr 
                165                 170                 175     


Ser Arg Gly Arg Thr Met Asn Ile Lys Ser Ala Thr Trp Lys Val Leu 
            180                 185                 190         


His Cys Thr Gly His Ile His Val Tyr Asp Thr Asn Ser Asn Gln Pro 
        195                 200                 205             


Gln Cys Gly Tyr Lys Lys Pro Pro Met Thr Cys Leu Val Leu Ile Cys 
    210                 215                 220                 


Glu Pro Ile Pro His Pro Ser Asn Ile Glu Ile Pro Leu Asp Ser Lys 
225                 230                 235                 240 


Thr Phe Leu Ser Arg His Ser Leu Asp Met Lys Phe Ser Tyr Cys Asp 
                245                 250                 255     


Glu Arg Ile Thr Glu Leu Met Gly Tyr Glu Pro Glu Glu Leu Leu Gly 
            260                 265                 270         


Arg Ser Ile Tyr Glu Tyr Tyr His Ala Leu Asp Ser Asp His Leu Thr 
        275                 280                 285             


Lys Thr His His Asp Met Phe Thr Lys Gly Gln Val Thr Thr Gly Gln 
    290                 295                 300                 


Tyr Arg Met Leu Ala Lys Arg Gly Gly Tyr Val Trp Val Glu Thr Gln 
305                 310                 315                 320 


Ala Thr Val Ile Tyr Asn Thr Lys Asn Ser Gln Pro Gln Cys Ile Val 
                325                 330                 335     


Cys Val Asn Tyr Val Val Ser Gly Ile Ile Gln His Asp Leu Ile Phe 
            340                 345                 350         


Ser Leu Gln Gln Thr Glu Cys Val Leu Lys Pro Val Glu Ser Ser Asp 
        355                 360                 365             


Met Lys Met Thr Gln Leu Phe Thr Lys Val Glu Ser Glu Asp Thr Ser 
    370                 375                 380                 


Ser Leu Phe Asp Lys Leu Lys Lys Glu Pro Asp Ala Leu Thr Leu Leu 
385                 390                 395                 400 


Ala Pro Ala Ala Gly Asp Thr Ile Ile Ser Leu Asp Phe Gly Ser Asn 
                405                 410                 415     


Asp Thr Glu Thr Asp Asp Gln Gln Leu Glu Glu Val Pro Leu Tyr Asn 
            420                 425                 430         


Asp Val Met Leu Pro Ser Pro Asn Glu Lys Leu Gln Asn Ile Asn Leu 
        435                 440                 445             


Ala Met Ser Pro Leu Pro Thr Ala Glu Thr Pro Lys Pro Leu Arg Ser 
    450                 455                 460                 


Ser Ala Asp Pro Ala Leu Asn Gln Glu Val Ala Leu Lys Leu Glu Pro 
465                 470                 475                 480 


Asn Pro Glu Ser Leu Glu Leu Ser Phe Thr Met Pro Gln Ile Gln Asp 
                485                 490                 495     


Gln Thr Pro Ser Pro Ser Asp Gly Ser Thr Arg Gln Ser Ser Pro Glu 
            500                 505                 510         


Pro Asn Ser Pro Ser Glu Tyr Cys Phe Tyr Val Asp Ser Asp Met Val 
        515                 520                 525             


Asn Glu Phe Lys Leu Glu Leu Val Glu Lys Leu Phe Ala Glu Asp Thr 
    530                 535                 540                 


Glu Ala Lys Asn Pro Phe Ser Thr Gln Asp Thr Asp Leu Asp Leu Glu 
545                 550                 555                 560 


Met Leu Ala Pro Tyr Ile Pro Met Asp Asp Asp Phe Gln Leu Arg Ser 
                565                 570                 575     


Phe Asp Gln Leu Ser Pro Leu Glu Ser Ser Ser Ala Ser Pro Glu Ser 
            580                 585                 590         


Ala Ser Pro Gln Ser Thr Val Thr Val Phe Gln Gln Thr Gln Ile Gln 
        595                 600                 605             


Glu Pro Thr Ala Asn Ala Thr Thr Thr Thr Ala Thr Thr Asp Glu Leu 
    610                 615                 620                 


Lys Thr Val Thr Lys Asp Arg Met Glu Asp Ile Lys Ile Leu Ile Ala 
625                 630                 635                 640 


Ser Pro Ser Pro Thr His Ile His Lys Glu Thr Thr Ser Ala Thr Ser 
                645                 650                 655     


Ser Pro Tyr Arg Asp Thr Gln Ser Arg Thr Ala Ser Pro Asn Arg Ala 
            660                 665                 670         


Gly Lys Gly Val Ile Glu Gln Thr Glu Lys Ser His Pro Arg Ser Pro 
        675                 680                 685             


Asn Val Leu Ser Val Ala Leu Ser Gln Arg Thr Thr Val Pro Glu Glu 
    690                 695                 700                 


Glu Leu Asn Pro Lys Ile Leu Ala Leu Gln Asn Ala Gln Arg Lys Arg 
705                 710                 715                 720 


Lys Met Glu His Asp Gly Ser Leu Phe Gln Ala Val Gly Ile Gly Thr 
                725                 730                 735     


Leu Leu Gln Gln Pro Asp Asp His Ala Ala Thr Thr Ser Leu Ser Trp 
            740                 745                 750         


Lys Arg Val Lys Gly Cys Lys Ser Ser Glu Gln Asn Gly Met Glu Gln 
        755                 760                 765             


Lys Thr Ile Ile Leu Ile Pro Ser Asp Leu Ala Cys Arg Leu Leu Gly 
    770                 775                 780                 


Gln Ser Met Asp Glu Ser Gly Leu Pro Gln Leu Thr Ser Tyr Asp Cys 
785                 790                 795                 800 


Glu Val Asn Ala Pro Ile Gln Gly Ser Arg Asn Leu Leu Gln Gly Glu 
                805                 810                 815     


Glu Leu Leu Arg Ala Leu Asp Gln Val Asn 
            820                 825     


<210>  3658
<211>  312
<212>  PRT
<213>  homo sapiens

<400>  3658

Met Ser Ala Phe Ser Glu Ala Ala Leu Glu Lys Lys Leu Ser Glu Leu 
1               5                   10                  15      


Ser Asn Ser Gln Gln Ser Val Gln Thr Leu Ser Leu Trp Leu Ile His 
            20                  25                  30          


His Arg Lys His Ser Arg Pro Ile Val Thr Val Trp Glu Arg Glu Leu 
        35                  40                  45              


Arg Lys Ala Lys Pro Asn Arg Lys Leu Thr Phe Leu Tyr Leu Ala Asn 
    50                  55                  60                  


Asp Val Ile Gln Asn Ser Lys Arg Lys Gly Pro Glu Phe Thr Lys Asp 
65                  70                  75                  80  


Phe Ala Pro Val Ile Val Glu Ala Phe Lys His Val Ser Ser Glu Thr 
                85                  90                  95      


Asp Glu Ser Cys Lys Lys His Leu Gly Arg Val Leu Ser Ile Trp Glu 
            100                 105                 110         


Glu Arg Ser Val Tyr Glu Asn Asp Val Leu Glu Gln Leu Lys Gln Ala 
        115                 120                 125             


Leu Tyr Gly Asp Lys Lys Pro Arg Lys Arg Thr Tyr Glu Gln Ile Lys 
    130                 135                 140                 


Val Asp Glu Asn Glu Asn Cys Ser Ser Leu Gly Ser Pro Ser Glu Pro 
145                 150                 155                 160 


Pro Gln Thr Leu Asp Leu Val Arg Ala Leu Gln Asp Leu Glu Asn Ala 
                165                 170                 175     


Ala Ser Gly Asp Ala Ala Val His Gln Arg Ile Ala Ser Leu Pro Val 
            180                 185                 190         


Glu Val Gln Glu Val Ser Leu Leu Asp Lys Ile Thr Asp Lys Glu Ser 
        195                 200                 205             


Gly Glu Arg Leu Ser Lys Met Val Glu Asp Ala Cys Met Leu Leu Ala 
    210                 215                 220                 


Asp Tyr Asn Gly Arg Leu Ala Ala Glu Ile Asp Asp Arg Lys Gln Leu 
225                 230                 235                 240 


Thr Arg Met Leu Ala Asp Phe Leu Arg Cys Gln Lys Glu Ala Leu Ala 
                245                 250                 255     


Glu Lys Glu His Lys Leu Glu Glu Tyr Lys Arg Lys Leu Ala Arg Val 
            260                 265                 270         


Ser Leu Val Arg Lys Glu Leu Arg Ser Arg Ile Gln Ser Leu Pro Asp 
        275                 280                 285             


Leu Ser Arg Leu Pro Asn Val Thr Gly Ser His Met His Leu Pro Phe 
    290                 295                 300                 


Ala Gly Asp Ile Tyr Ser Glu Asp 
305                 310         


<210>  3659
<211>  504
<212>  PRT
<213>  homo sapiens

<400>  3659

Met Lys Ala Ala Tyr Thr Ala Tyr Arg Cys Leu Thr Lys Asp Leu Glu 
1               5                   10                  15      


Gly Cys Ala Met Asn Pro Glu Leu Thr Met Glu Ser Leu Gly Thr Leu 
            20                  25                  30          


His Gly Pro Ala Gly Gly Gly Ser Gly Gly Gly Gly Gly Gly Gly Gly 
        35                  40                  45              


Gly Gly Gly Gly Gly Gly Pro Gly His Glu Gln Glu Leu Leu Ala Ser 
    50                  55                  60                  


Pro Ser Pro His His Ala Gly Arg Gly Ala Ala Gly Ser Leu Arg Gly 
65                  70                  75                  80  


Pro Pro Pro Pro Pro Thr Ala His Gln Glu Leu Gly Thr Ala Ala Ala 
                85                  90                  95      


Ala Ala Ala Ala Ala Ser Arg Ser Ala Met Val Thr Ser Met Ala Ser 
            100                 105                 110         


Ile Leu Asp Gly Gly Asp Tyr Arg Pro Glu Leu Ser Ile Pro Leu His 
        115                 120                 125             


His Ala Met Ser Met Ser Cys Asp Ser Ser Pro Pro Gly Met Gly Met 
    130                 135                 140                 


Ser Asn Thr Tyr Thr Thr Leu Thr Pro Leu Gln Pro Leu Pro Pro Ile 
145                 150                 155                 160 


Ser Thr Val Ser Asp Lys Phe His His Pro His Pro His His His Pro 
                165                 170                 175     


His His His His His His His His Gln Arg Leu Ser Gly Asn Val Ser 
            180                 185                 190         


Gly Ser Phe Thr Leu Met Arg Asp Glu Arg Gly Leu Pro Ala Met Asn 
        195                 200                 205             


Asn Leu Tyr Ser Pro Tyr Lys Glu Met Pro Gly Met Ser Gln Ser Leu 
    210                 215                 220                 


Ser Pro Leu Ala Ala Thr Pro Leu Gly Asn Gly Leu Gly Gly Leu His 
225                 230                 235                 240 


Asn Ala Gln Gln Ser Leu Pro Asn Tyr Gly Pro Pro Gly His Asp Lys 
                245                 250                 255     


Met Leu Ser Pro Asn Phe Asp Ala His His Thr Ala Met Leu Thr Arg 
            260                 265                 270         


Gly Glu Gln His Leu Ser Arg Gly Leu Gly Thr Pro Pro Ala Ala Met 
        275                 280                 285             


Met Ser His Leu Asn Gly Leu His His Pro Gly His Thr Gln Ser His 
    290                 295                 300                 


Gly Pro Val Leu Ala Pro Ser Arg Glu Arg Pro Pro Ser Ser Ser Ser 
305                 310                 315                 320 


Gly Ser Gln Val Ala Thr Ser Gly Gln Leu Glu Glu Ile Asn Thr Lys 
                325                 330                 335     


Glu Val Ala Gln Arg Ile Thr Ala Glu Leu Lys Arg Tyr Ser Ile Pro 
            340                 345                 350         


Gln Ala Ile Phe Ala Gln Arg Val Leu Cys Arg Ser Gln Gly Thr Leu 
        355                 360                 365             


Ser Asp Leu Leu Arg Asn Pro Lys Pro Trp Ser Lys Leu Lys Ser Gly 
    370                 375                 380                 


Arg Glu Thr Phe Arg Arg Met Trp Lys Trp Leu Gln Glu Pro Glu Phe 
385                 390                 395                 400 


Gln Arg Met Ser Ala Leu Arg Leu Ala Ala Cys Lys Arg Lys Glu Gln 
                405                 410                 415     


Glu Pro Asn Lys Asp Arg Asn Asn Ser Gln Lys Lys Ser Arg Leu Val 
            420                 425                 430         


Phe Thr Asp Leu Gln Arg Arg Thr Leu Phe Ala Ile Phe Lys Glu Asn 
        435                 440                 445             


Lys Arg Pro Ser Lys Glu Met Gln Ile Thr Ile Ser Gln Gln Leu Gly 
    450                 455                 460                 


Leu Glu Leu Thr Thr Val Ser Asn Phe Phe Met Asn Ala Arg Arg Arg 
465                 470                 475                 480 


Ser Leu Glu Lys Trp Gln Asp Asp Leu Ser Thr Gly Gly Ser Ser Ser 
                485                 490                 495     


Thr Ser Ser Thr Cys Thr Lys Ala 
            500                 


<210>  3660
<211>  469
<212>  PRT
<213>  homo sapiens

<400>  3660

Met Glu Glu Arg Met Glu Met Ile Ser Glu Arg Pro Lys Glu Ser Met 
1               5                   10                  15      


Tyr Ser Trp Asn Lys Thr Ala Glu Lys Ser Asp Phe Glu Ala Val Glu 
            20                  25                  30          


Ala Leu Met Ser Met Ser Cys Ser Trp Lys Ser Asp Phe Lys Lys Tyr 
        35                  40                  45              


Val Glu Asn Arg Pro Val Thr Pro Val Ser Asp Leu Ser Glu Glu Glu 
    50                  55                  60                  


Asn Leu Leu Pro Gly Thr Pro Asp Phe His Thr Ile Pro Ala Phe Cys 
65                  70                  75                  80  


Leu Thr Pro Pro Tyr Ser Pro Ser Asp Phe Glu Pro Ser Gln Val Ser 
                85                  90                  95      


Asn Leu Met Ala Pro Ala Pro Ser Thr Val His Phe Lys Ser Leu Ser 
            100                 105                 110         


Asp Thr Ala Lys Pro His Ile Ala Ala Pro Phe Lys Glu Glu Glu Lys 
        115                 120                 125             


Ser Pro Val Ser Ala Pro Lys Leu Pro Lys Ala Gln Ala Thr Ser Val 
    130                 135                 140                 


Ile Arg His Thr Ala Asp Ala Gln Leu Cys Asn His Gln Thr Cys Pro 
145                 150                 155                 160 


Met Lys Ala Ala Ser Ile Leu Asn Tyr Gln Asn Asn Ser Phe Arg Arg 
                165                 170                 175     


Arg Thr His Leu Asn Val Glu Ala Ala Arg Lys Asn Ile Pro Cys Ala 
            180                 185                 190         


Ala Val Ser Pro Asn Arg Ser Lys Cys Glu Arg Asn Thr Val Ala Asp 
        195                 200                 205             


Val Asp Glu Lys Ala Ser Ala Ala Leu Tyr Asp Phe Ser Val Pro Ser 
    210                 215                 220                 


Ser Glu Thr Val Ile Cys Arg Ser Gln Pro Ala Pro Val Ser Pro Gln 
225                 230                 235                 240 


Gln Lys Ser Val Leu Val Ser Pro Pro Ala Val Ser Ala Gly Gly Val 
                245                 250                 255     


Pro Pro Met Pro Val Ile Cys Gln Met Val Pro Leu Pro Ala Asn Asn 
            260                 265                 270         


Pro Val Val Thr Thr Val Val Pro Ser Thr Pro Pro Ser Gln Pro Pro 
        275                 280                 285             


Ala Val Cys Pro Pro Val Val Phe Met Gly Thr Gln Val Pro Lys Gly 
    290                 295                 300                 


Ala Val Met Phe Val Val Pro Gln Pro Val Val Gln Ser Ser Lys Pro 
305                 310                 315                 320 


Pro Val Val Ser Pro Asn Gly Thr Arg Leu Ser Pro Ile Ala Pro Ala 
                325                 330                 335     


Pro Gly Phe Ser Pro Ser Ala Ala Lys Val Thr Pro Gln Ile Asp Ser 
            340                 345                 350         


Ser Arg Ile Arg Ser His Ile Cys Ser His Pro Gly Cys Gly Lys Thr 
        355                 360                 365             


Tyr Phe Lys Ser Ser His Leu Lys Ala His Thr Arg Thr His Thr Gly 
    370                 375                 380                 


Glu Lys Pro Phe Ser Cys Ser Trp Lys Gly Cys Glu Arg Arg Phe Ala 
385                 390                 395                 400 


Arg Ser Asp Glu Leu Ser Arg His Arg Arg Thr His Thr Gly Glu Lys 
                405                 410                 415     


Lys Phe Ala Cys Pro Met Cys Asp Arg Arg Phe Met Arg Ser Asp His 
            420                 425                 430         


Leu Thr Lys His Ala Arg Arg His Leu Ser Ala Lys Lys Leu Pro Asn 
        435                 440                 445             


Trp Gln Met Glu Val Ser Lys Leu Asn Asp Ile Ala Leu Pro Pro Thr 
    450                 455                 460                 


Pro Ala Pro Thr Gln 
465                 


<210>  3661
<211>  721
<212>  PRT
<213>  homo sapiens

<400>  3661

Met Leu Leu Pro Val Phe Thr Leu Lys Leu Arg His Lys Ile Ser Pro 
1               5                   10                  15      


Arg Met Val Ala Ile Gly Arg Tyr Asp Gly Thr His Pro Cys Leu Ala 
            20                  25                  30          


Ala Ala Thr Gln Thr Gly Lys Val Phe Ile His Asn Pro His Thr Arg 
        35                  40                  45              


Asn Gln His Val Ser Ala Ser Arg Val Phe Gln Ser Pro Leu Glu Ser 
    50                  55                  60                  


Asp Val Ser Leu Leu Asn Ile Asn Gln Ala Val Ser Cys Leu Thr Ala 
65                  70                  75                  80  


Gly Val Leu Asn Pro Glu Leu Gly Tyr Asp Ala Leu Leu Val Gly Thr 
                85                  90                  95      


Gln Thr Asn Leu Leu Ala Tyr Asp Val Tyr Asn Asn Ser Asp Leu Phe 
            100                 105                 110         


Tyr Arg Glu Val Ala Asp Gly Ala Asn Ala Ile Val Leu Gly Thr Leu 
        115                 120                 125             


Gly Asp Ile Ser Ser Pro Leu Ala Ile Ile Gly Gly Asn Cys Ala Leu 
    130                 135                 140                 


Gln Gly Phe Asn His Glu Gly Ser Asp Leu Phe Trp Thr Val Thr Gly 
145                 150                 155                 160 


Asp Asn Val Asn Ser Leu Ala Leu Cys Asp Phe Asp Gly Asp Gly Lys 
                165                 170                 175     


Lys Glu Leu Leu Val Gly Ser Glu Asp Phe Asp Ile Arg Val Phe Lys 
            180                 185                 190         


Glu Asp Glu Ile Val Ala Glu Met Thr Glu Thr Glu Ile Val Thr Ser 
        195                 200                 205             


Leu Cys Pro Met Tyr Gly Ser Arg Phe Gly Tyr Ala Leu Ser Asn Gly 
    210                 215                 220                 


Thr Val Gly Val Tyr Asp Lys Thr Ser Arg Tyr Trp Arg Ile Lys Ser 
225                 230                 235                 240 


Lys Asn His Ala Met Ser Ile His Ala Phe Asp Leu Asn Ser Asp Gly 
                245                 250                 255     


Val Asn Glu Leu Ile Thr Gly Trp Ser Asn Gly Lys Val Asp Ala Arg 
            260                 265                 270         


Ser Asp Arg Thr Gly Glu Val Ile Phe Lys Asp Asn Phe Ser Ser Ala 
        275                 280                 285             


Ile Ala Gly Val Val Glu Gly Asp Tyr Arg Met Asp Gly His Ile Gln 
    290                 295                 300                 


Leu Ile Cys Cys Ser Val Asp Gly Glu Ile Arg Gly Tyr Leu Pro Gly 
305                 310                 315                 320 


Thr Ala Glu Met Arg Gly Asn Leu Met Asp Thr Ser Ala Glu Gln Asp 
                325                 330                 335     


Leu Ile Arg Glu Leu Ser Gln Lys Lys Gln Asn Leu Leu Leu Glu Leu 
            340                 345                 350         


Arg Asn Tyr Glu Glu Asn Ala Lys Ala Glu Leu Ala Ser Pro Leu Asn 
        355                 360                 365             


Glu Ala Asp Gly His Arg Gly Ile Ile Pro Ala Asn Thr Arg Leu His 
    370                 375                 380                 


Thr Thr Leu Ser Val Ser Leu Gly Asn Glu Thr Gln Thr Ala His Thr 
385                 390                 395                 400 


Glu Leu Arg Ile Ser Thr Ser Asn Asp Thr Ile Ile Arg Ala Val Leu 
                405                 410                 415     


Ile Phe Ala Glu Gly Ile Phe Thr Gly Glu Ser His Val Val His Pro 
            420                 425                 430         


Ser Ile His Asn Leu Ser Ser Ser Ile Cys Ile Pro Ile Val Pro Pro 
        435                 440                 445             


Lys Asp Val Pro Val Asp Leu His Leu Lys Ala Phe Val Gly Tyr Arg 
    450                 455                 460                 


Ser Ser Thr Gln Phe His Val Phe Glu Ser Thr Arg Gln Leu Pro Arg 
465                 470                 475                 480 


Phe Ser Met Tyr Ala Leu Thr Ser Leu Asp Pro Ala Ser Glu Pro Ile 
                485                 490                 495     


Ser Tyr Val Asn Phe Thr Ile Ala Glu Arg Ala Gln Arg Val Val Val 
            500                 505                 510         


Trp Leu Gly Gln Asn Phe Leu Leu Pro Glu Asp Thr His Ile Gln Asn 
        515                 520                 525             


Ala Pro Phe Gln Val Cys Phe Thr Ser Leu Arg Asn Gly Gly His Leu 
    530                 535                 540                 


His Ile Lys Ile Lys Leu Ser Gly Glu Ile Thr Ile Asn Thr Asp Asp 
545                 550                 555                 560 


Ile Asp Leu Ala Gly Asp Ile Ile Gln Ser Met Ala Ser Phe Phe Ala 
                565                 570                 575     


Ile Glu Asp Leu Gln Val Glu Ala Asp Phe Pro Val Tyr Phe Glu Glu 
            580                 585                 590         


Leu Arg Lys Val Leu Val Lys Val Asp Glu Tyr His Ser Val His Gln 
        595                 600                 605             


Lys Leu Ser Ala Asp Met Ala Asp His Ser Asn Leu Ile Arg Ser Leu 
    610                 615                 620                 


Leu Val Gly Ala Glu Asp Ala Arg Leu Met Arg Asp Met Lys Thr Met 
625                 630                 635                 640 


Lys Ser Arg Tyr Met Glu Leu Tyr Asp Leu Asn Arg Asp Leu Leu Asn 
                645                 650                 655     


Gly Tyr Lys Ile Arg Cys Asn Asn His Thr Glu Leu Leu Gly Asn Leu 
            660                 665                 670         


Lys Ala Val Asn Gln Ala Ile Gln Arg Ala Gly Arg Leu Arg Val Gly 
        675                 680                 685             


Lys Pro Lys Asn Gln Val Ile Thr Ala Cys Arg Asp Ala Ile Arg Ser 
    690                 695                 700                 


Asn Asn Ile Asn Thr Leu Phe Lys Ile Met Arg Val Gly Thr Ala Ser 
705                 710                 715                 720 


Ser 
    


<210>  3662
<211>  254
<212>  PRT
<213>  homo sapiens

<400>  3662

Met Asn Ser Arg Gln Ala Trp Arg Leu Phe Leu Ser Gln Gly Arg Gly 
1               5                   10                  15      


Asp Arg Trp Val Ser Arg Pro Arg Gly His Phe Ser Pro Ala Leu Arg 
            20                  25                  30          


Arg Glu Phe Phe Thr Thr Thr Thr Lys Glu Gly Tyr Asp Arg Arg Pro 
        35                  40                  45              


Val Asp Ile Thr Pro Leu Glu Gln Arg Lys Leu Thr Phe Asp Thr His 
    50                  55                  60                  


Ala Leu Val Gln Asp Leu Glu Thr His Gly Phe Asp Lys Thr Gln Ala 
65                  70                  75                  80  


Glu Thr Ile Val Ser Ala Leu Thr Ala Leu Ser Asn Val Ser Leu Asp 
                85                  90                  95      


Thr Ile Tyr Lys Glu Met Val Thr Gln Ala Gln Gln Glu Ile Thr Val 
            100                 105                 110         


Gln Gln Leu Met Ala His Leu Asp Ala Ile Arg Lys Asp Met Val Ile 
        115                 120                 125             


Leu Glu Lys Ser Glu Phe Ala Asn Leu Arg Ala Glu Asn Glu Lys Met 
    130                 135                 140                 


Lys Ile Glu Leu Asp Gln Val Lys Gln Gln Leu Met His Glu Thr Ser 
145                 150                 155                 160 


Arg Ile Arg Ala Asp Asn Lys Leu Asp Ile Asn Leu Glu Arg Ser Arg 
                165                 170                 175     


Val Thr Asp Met Phe Thr Asp Gln Glu Lys Gln Leu Met Glu Thr Thr 
            180                 185                 190         


Thr Glu Phe Thr Lys Lys Asp Thr Gln Thr Lys Ser Ile Ile Ser Glu 
        195                 200                 205             


Thr Ser Asn Lys Ile Asp Ala Glu Ile Ala Ser Leu Lys Thr Leu Met 
    210                 215                 220                 


Glu Ser Asn Lys Leu Glu Thr Ile Arg Tyr Leu Ala Ala Ser Val Phe 
225                 230                 235                 240 


Thr Cys Leu Ala Ile Ala Leu Gly Phe Tyr Arg Phe Trp Lys 
                245                 250                 


<210>  3663
<211>  457
<212>  PRT
<213>  homo sapiens

<400>  3663

Met Thr Thr Asp Glu Gly Ala Lys Asn Asn Glu Glu Ser Pro Thr Ala 
1               5                   10                  15      


Thr Val Ala Glu Gln Gly Glu Asp Ile Thr Ser Lys Lys Asp Arg Gly 
            20                  25                  30          


Val Leu Lys Ile Val Lys Arg Val Gly Asn Gly Glu Glu Thr Pro Met 
        35                  40                  45              


Ile Gly Asp Lys Val Tyr Val His Tyr Lys Gly Lys Leu Ser Asn Gly 
    50                  55                  60                  


Lys Lys Phe Asp Ser Ser His Asp Arg Asn Glu Pro Phe Val Phe Ser 
65                  70                  75                  80  


Leu Gly Lys Gly Gln Val Ile Lys Ala Trp Asp Ile Gly Val Ala Thr 
                85                  90                  95      


Met Lys Lys Gly Glu Ile Cys His Leu Leu Cys Lys Pro Glu Tyr Ala 
            100                 105                 110         


Tyr Gly Ser Ala Gly Ser Leu Pro Lys Ile Pro Ser Asn Ala Thr Leu 
        115                 120                 125             


Phe Phe Glu Ile Glu Leu Leu Asp Phe Lys Gly Glu Asp Leu Phe Glu 
    130                 135                 140                 


Asp Gly Gly Ile Ile Arg Arg Thr Lys Arg Lys Gly Glu Gly Tyr Ser 
145                 150                 155                 160 


Asn Pro Asn Glu Gly Ala Thr Val Glu Ile His Leu Glu Gly Arg Cys 
                165                 170                 175     


Gly Gly Arg Met Phe Asp Cys Arg Asp Val Ala Phe Thr Val Gly Glu 
            180                 185                 190         


Gly Glu Asp His Asp Ile Pro Ile Gly Ile Asp Lys Ala Leu Glu Lys 
        195                 200                 205             


Met Gln Arg Glu Glu Gln Cys Ile Leu Tyr Leu Gly Pro Arg Tyr Gly 
    210                 215                 220                 


Phe Gly Glu Ala Gly Lys Pro Lys Phe Gly Ile Glu Pro Asn Ala Glu 
225                 230                 235                 240 


Leu Ile Tyr Glu Val Thr Leu Lys Ser Phe Glu Lys Ala Lys Glu Ser 
                245                 250                 255     


Trp Glu Met Asp Thr Lys Glu Lys Leu Glu Gln Ala Ala Ile Val Lys 
            260                 265                 270         


Glu Lys Gly Thr Val Tyr Phe Lys Gly Gly Lys Tyr Met Gln Ala Val 
        275                 280                 285             


Ile Gln Tyr Gly Lys Ile Val Ser Trp Leu Glu Met Glu Tyr Gly Leu 
    290                 295                 300                 


Ser Glu Lys Glu Ser Lys Ala Ser Glu Ser Phe Leu Leu Ala Ala Phe 
305                 310                 315                 320 


Leu Asn Leu Ala Met Cys Tyr Leu Lys Leu Arg Glu Tyr Thr Lys Ala 
                325                 330                 335     


Val Glu Cys Cys Asp Lys Ala Leu Gly Leu Asp Ser Ala Asn Glu Lys 
            340                 345                 350         


Gly Leu Tyr Arg Arg Gly Glu Ala Gln Leu Leu Met Asn Glu Phe Glu 
        355                 360                 365             


Ser Ala Lys Gly Asp Phe Glu Lys Val Leu Glu Val Asn Pro Gln Asn 
    370                 375                 380                 


Lys Ala Ala Arg Leu Gln Ile Ser Met Cys Gln Lys Lys Ala Lys Glu 
385                 390                 395                 400 


His Asn Glu Arg Asp Arg Arg Ile Tyr Ala Asn Met Phe Lys Lys Phe 
                405                 410                 415     


Ala Glu Gln Asp Ala Lys Glu Glu Ala Asn Lys Ala Met Gly Lys Lys 
            420                 425                 430         


Thr Ser Glu Gly Val Thr Asn Glu Lys Gly Thr Asp Ser Gln Ala Met 
        435                 440                 445             


Glu Glu Glu Lys Pro Glu Gly His Val 
    450                 455         


<210>  3664
<211>  1250
<212>  PRT
<213>  homo sapiens

<400>  3664

Met Lys Pro Pro Gln Gln Ser Leu Tyr Leu Leu Val Asp Ser Val Asp 
1               5                   10                  15      


Glu Gly Cys Asn Ile Thr Glu Gly Glu Gln Thr Ser Thr Ser Leu Ser 
            20                  25                  30          


Gly Thr Val Ala Ala Leu Leu Ala Gly His His Glu Phe Phe Pro Pro 
        35                  40                  45              


Trp Leu Leu Leu Leu Cys Ser Ala Arg Lys Gln Ser Lys Ala Val Thr 
    50                  55                  60                  


Lys Met Phe Thr Gly Phe Arg Lys Ile Ser Leu Asp Asp Leu Arg Lys 
65                  70                  75                  80  


Ala Tyr Ile Val Lys Asp Val Gln Gln Tyr Ile Leu His Arg Leu Asp 
                85                  90                  95      


Gln Glu Glu Ala Leu Arg Gln His Leu Thr Lys Glu Thr Ala Glu Met 
            100                 105                 110         


Leu Asn Gln Leu His Ile Lys Ser Ser Gly Cys Phe Leu Tyr Leu Glu 
        115                 120                 125             


Arg Val Leu Asp Gly Val Val Glu Asn Phe Ile Met Leu Arg Glu Ile 
    130                 135                 140                 


Arg Asp Ile Pro Gly Thr Leu Asn Gly Leu Tyr Leu Trp Leu Cys Gln 
145                 150                 155                 160 


Arg Leu Phe Val Arg Lys Gln Phe Ala Lys Val Gln Pro Ile Leu Asn 
                165                 170                 175     


Val Ile Leu Ala Ala Cys Arg Pro Leu Thr Ile Thr Glu Leu Tyr His 
            180                 185                 190         


Ala Val Trp Thr Lys Asn Met Ser Leu Thr Leu Glu Asp Phe Gln Arg 
        195                 200                 205             


Lys Leu Asp Ile Leu Ser Lys Leu Leu Val Asp Gly Leu Gly Asn Thr 
    210                 215                 220                 


Lys Ile Leu Phe His Tyr Ser Phe Ala Glu Trp Leu Leu Asp Val Lys 
225                 230                 235                 240 


His Cys Thr Gln Lys Tyr Leu Cys Asn Ala Ala Glu Gly His Arg Met 
                245                 250                 255     


Leu Ala Met Ser Tyr Thr Cys Gln Ala Lys Asn Leu Thr Pro Leu Glu 
            260                 265                 270         


Ala Gln Glu Phe Ala Leu His Leu Ile Asn Ser Asn Leu Gln Leu Glu 
        275                 280                 285             


Thr Ala Glu Leu Ala Leu Trp Met Ile Trp Asn Gly Thr Pro Val Arg 
    290                 295                 300                 


Asp Ser Leu Ser Thr Leu Ile Pro Lys Glu Gln Glu Val Leu Gln Leu 
305                 310                 315                 320 


Leu Val Lys Ala Gly Ala His Val Asn Ser Glu Asp Asp Arg Thr Ser 
                325                 330                 335     


Cys Ile Val Arg Gln Ala Leu Glu Arg Glu Asp Ser Ile Arg Thr Leu 
            340                 345                 350         


Leu Asp Asn Gly Ala Ser Val Asn Gln Cys Asp Ser Asn Gly Arg Thr 
        355                 360                 365             


Leu Leu Ala Asn Ala Ala Tyr Ser Gly Ser Leu Asp Val Val Asn Leu 
    370                 375                 380                 


Leu Val Ser Arg Gly Ala Asp Leu Glu Ile Glu Asp Ala His Gly His 
385                 390                 395                 400 


Thr Pro Leu Thr Leu Ala Ala Arg Gln Gly His Thr Lys Val Val Asn 
                405                 410                 415     


Cys Leu Ile Gly Cys Gly Ala Asn Ile Asn His Thr Asp Gln Asp Gly 
            420                 425                 430         


Trp Thr Ala Leu Arg Ser Ala Ala Trp Gly Gly His Thr Glu Val Val 
        435                 440                 445             


Ser Ala Leu Leu Tyr Ala Gly Val Lys Val Asp Cys Ala Asp Ala Asp 
    450                 455                 460                 


Ser Arg Thr Ala Leu Arg Ala Ala Ala Trp Gly Gly His Glu Asp Ile 
465                 470                 475                 480 


Val Leu Asn Leu Leu Gln His Gly Ala Glu Val Asn Lys Ala Asp Asn 
                485                 490                 495     


Glu Gly Arg Thr Ala Leu Ile Ala Ala Ala Tyr Met Gly His Arg Glu 
            500                 505                 510         


Ile Val Glu His Leu Leu Asp His Gly Ala Glu Val Asn His Glu Asp 
        515                 520                 525             


Val Asp Gly Arg Thr Ala Leu Ser Val Ala Ala Leu Cys Val Pro Ala 
    530                 535                 540                 


Ser Lys Gly His Ala Ser Val Val Ser Leu Leu Ile Asp Arg Gly Ala 
545                 550                 555                 560 


Glu Val Asp His Cys Asp Lys Asp Gly Met Thr Pro Leu Leu Val Ala 
                565                 570                 575     


Ala Tyr Glu Gly His Val Asp Val Val Asp Leu Leu Leu Glu Gly Gly 
            580                 585                 590         


Ala Asp Val Asp His Thr Asp Asn Asn Gly Arg Thr Pro Leu Leu Ala 
        595                 600                 605             


Ala Ala Ser Met Gly His Ala Ser Val Val Asn Thr Leu Leu Phe Trp 
    610                 615                 620                 


Gly Ala Ala Val Asp Ser Ile Asp Ser Glu Gly Arg Thr Val Leu Ser 
625                 630                 635                 640 


Ile Ala Ser Ala Gln Gly Asn Val Glu Val Val Arg Thr Leu Leu Asp 
                645                 650                 655     


Arg Gly Leu Asp Glu Asn His Arg Asp Asp Ala Gly Trp Thr Pro Leu 
            660                 665                 670         


His Met Ala Ala Phe Glu Gly His Arg Leu Ile Cys Glu Ala Leu Ile 
        675                 680                 685             


Glu Gln Gly Ala Arg Thr Asn Glu Ile Asp Asn Asp Gly Arg Ile Pro 
    690                 695                 700                 


Phe Ile Leu Ala Ser Gln Glu Gly His Tyr Asp Cys Val Gln Ile Leu 
705                 710                 715                 720 


Leu Glu Asn Lys Ser Asn Ile Asp Gln Arg Gly Tyr Asp Gly Arg Asn 
                725                 730                 735     


Ala Leu Arg Val Ala Ala Leu Glu Gly His Arg Asp Ile Val Glu Leu 
            740                 745                 750         


Leu Phe Ser His Gly Ala Asp Val Asn Cys Lys Asp Ala Asp Gly Arg 
        755                 760                 765             


Pro Thr Leu Tyr Ile Leu Ala Leu Glu Asn Gln Leu Thr Met Ala Glu 
    770                 775                 780                 


Tyr Phe Leu Glu Asn Gly Ala Asn Val Glu Ala Ser Asp Ala Glu Gly 
785                 790                 795                 800 


Arg Thr Ala Leu His Val Ser Cys Trp Gln Gly His Met Glu Met Val 
                805                 810                 815     


Gln Val Leu Ile Ala Tyr His Ala Asp Val Asn Ala Ala Asp Asn Glu 
            820                 825                 830         


Lys Arg Ser Ala Leu Gln Ser Ala Ala Trp Gln Gly His Val Lys Val 
        835                 840                 845             


Val Gln Leu Leu Ile Glu His Gly Ala Val Val Asp His Thr Cys Asn 
    850                 855                 860                 


Gln Gly Ala Thr Ala Leu Cys Ile Ala Ala Gln Glu Gly His Ile Asp 
865                 870                 875                 880 


Val Val Gln Val Leu Leu Glu His Gly Ala Asp Pro Asn His Ala Asp 
                885                 890                 895     


Gln Phe Gly Arg Thr Ala Met Arg Val Ala Ala Lys Asn Gly His Ser 
            900                 905                 910         


Gln Ile Ile Lys Leu Leu Glu Lys Tyr Gly Ala Ser Ser Leu Asn Gly 
        915                 920                 925             


Cys Ser Pro Ser Pro Val His Thr Met Glu Gln Lys Pro Leu Gln Ser 
    930                 935                 940                 


Leu Ser Ser Lys Val Gln Ser Leu Thr Ile Lys Ser Asn Ser Ser Gly 
945                 950                 955                 960 


Ser Thr Gly Gly Gly Asp Met Gln Pro Ser Leu Arg Gly Leu Pro Asn 
                965                 970                 975     


Gly Pro Thr His Ala Phe Ser Ser Pro Ser Glu Ser Pro Asp Ser Thr 
            980                 985                 990         


Val Asp Arg Gln Lys Ser Ser Leu  Ser Asn Asn Ser Leu  Lys Ser Ser 
        995                 1000                 1005             


Lys Asn  Ser Ser Leu Arg Thr  Thr Ser Ser Thr Ala  Thr Ala Gln 
    1010                 1015                 1020             


Thr Val  Pro Ile Asp Ser Phe  His Asn Leu Ser Phe  Thr Glu Gln 
    1025                 1030                 1035             


Ile Gln  Gln His Ser Leu Pro  Arg Ser Arg Ser Arg  Gln Ser Ile 
    1040                 1045                 1050             


Val Ser  Pro Ser Ser Thr Thr  Gln Ser Leu Gly Gln  Ser His Asn 
    1055                 1060                 1065             


Ser Pro  Ser Ser Glu Phe Glu  Trp Ser Gln Val Lys  Pro Ser Leu 
    1070                 1075                 1080             


Lys Ser  Thr Lys Ala Ser Lys  Gly Gly Lys Ser Glu  Asn Ser Ala 
    1085                 1090                 1095             


Lys Ser  Gly Ser Ala Gly Lys  Lys Ala Lys Gln Ser  Asn Ser Ser 
    1100                 1105                 1110             


Gln Pro  Lys Val Leu Glu Tyr  Glu Met Thr Gln Phe  Asp Arg Arg 
    1115                 1120                 1125             


Gly Pro  Ile Ala Lys Ser Gly  Thr Ala Ala Pro Pro  Lys Gln Met 
    1130                 1135                 1140             


Pro Ala  Glu Ser Gln Cys Lys  Ile Met Ile Pro Ser  Ala Gln Gln 
    1145                 1150                 1155             


Glu Ile  Gly Arg Ser Gln Gln  Gln Phe Leu Ile His  Gln Gln Ser 
    1160                 1165                 1170             


Gly Glu  Gln Lys Lys Arg Asn  Gly Ile Met Thr Asn  Pro Asn Tyr 
    1175                 1180                 1185             


His Leu  Gln Ser Asn Gln Val  Phe Leu Gly Arg Val  Ser Val Pro 
    1190                 1195                 1200             


Arg Thr  Met Gln Asp Arg Gly  His Gln Glu Val Leu  Glu Gly Tyr 
    1205                 1210                 1215             


Pro Ser  Ser Glu Thr Glu Leu  Ser Leu Lys Gln Ala  Leu Lys Leu 
    1220                 1225                 1230             


Gln Ile  Glu Gly Ser Asp Pro  Ser Phe Asn Tyr Lys  Lys Glu Thr 
    1235                 1240                 1245             


Pro Leu  
    1250 


<210>  3665
<211>  899
<212>  PRT
<213>  homo sapiens

<400>  3665

Met Glu Ser Cys Tyr Asn Pro Gly Leu Asp Gly Ile Ile Glu Tyr Asp 
1               5                   10                  15      


Asp Phe Lys Leu Asn Ser Ser Ile Val Glu Pro Lys Glu Pro Ala Pro 
            20                  25                  30          


Glu Thr Ala Asp Gly Pro Tyr Leu Val Ile Val Glu Gln Pro Lys Gln 
        35                  40                  45              


Arg Gly Phe Arg Phe Arg Tyr Gly Cys Glu Gly Pro Ser His Gly Gly 
    50                  55                  60                  


Leu Pro Gly Ala Ser Ser Glu Lys Gly Arg Lys Thr Tyr Pro Thr Val 
65                  70                  75                  80  


Lys Ile Cys Asn Tyr Glu Gly Pro Ala Lys Ile Glu Val Asp Leu Val 
                85                  90                  95      


Thr His Ser Asp Pro Pro Arg Ala His Ala His Ser Leu Val Gly Lys 
            100                 105                 110         


Gln Cys Ser Glu Leu Gly Ile Cys Ala Val Ser Val Gly Pro Lys Asp 
        115                 120                 125             


Met Thr Ala Gln Phe Asn Asn Leu Gly Val Leu His Val Thr Lys Lys 
    130                 135                 140                 


Asn Met Met Gly Thr Met Ile Gln Lys Leu Gln Arg Gln Arg Leu Arg 
145                 150                 155                 160 


Ser Arg Pro Gln Gly Leu Thr Glu Ala Glu Gln Arg Glu Leu Glu Gln 
                165                 170                 175     


Glu Ala Lys Glu Leu Lys Lys Val Met Asp Leu Ser Ile Val Arg Leu 
            180                 185                 190         


Arg Phe Ser Ala Phe Leu Arg Ala Ser Asp Gly Ser Phe Ser Leu Pro 
        195                 200                 205             


Leu Lys Pro Val Ile Ser Gln Pro Ile His Asp Ser Lys Ser Pro Gly 
    210                 215                 220                 


Ala Ser Asn Leu Lys Ile Ser Arg Met Asp Lys Thr Ala Gly Ser Val 
225                 230                 235                 240 


Arg Gly Gly Asp Glu Val Tyr Leu Leu Cys Asp Lys Val Gln Lys Asp 
                245                 250                 255     


Asp Ile Glu Val Arg Phe Tyr Glu Asp Asp Glu Asn Gly Trp Gln Ala 
            260                 265                 270         


Phe Gly Asp Phe Ser Pro Thr Asp Val His Lys Gln Tyr Ala Ile Val 
        275                 280                 285             


Phe Arg Thr Pro Pro Tyr His Lys Met Lys Ile Glu Arg Pro Val Thr 
    290                 295                 300                 


Val Phe Leu Gln Leu Lys Arg Lys Arg Gly Gly Asp Val Ser Asp Ser 
305                 310                 315                 320 


Lys Gln Phe Thr Tyr Tyr Pro Leu Val Glu Asp Lys Glu Glu Val Gln 
                325                 330                 335     


Arg Lys Arg Arg Lys Ala Leu Pro Thr Phe Ser Gln Pro Phe Gly Gly 
            340                 345                 350         


Gly Ser His Met Gly Gly Gly Ser Gly Gly Ala Ala Gly Gly Tyr Gly 
        355                 360                 365             


Gly Ala Gly Gly Gly Gly Ser Leu Gly Phe Phe Pro Ser Ser Leu Ala 
    370                 375                 380                 


Tyr Ser Pro Tyr Gln Ser Gly Ala Gly Pro Met Gly Cys Tyr Pro Gly 
385                 390                 395                 400 


Gly Gly Gly Gly Ala Gln Met Ala Ala Thr Val Pro Ser Arg Asp Ser 
                405                 410                 415     


Gly Glu Glu Ala Ala Glu Pro Ser Ala Pro Ser Arg Thr Pro Gln Cys 
            420                 425                 430         


Glu Pro Gln Ala Pro Glu Met Leu Gln Arg Ala Arg Glu Tyr Asn Ala 
        435                 440                 445             


Arg Leu Phe Gly Leu Ala Gln Arg Ser Ala Arg Ala Leu Leu Asp Tyr 
    450                 455                 460                 


Gly Val Thr Ala Asp Ala Arg Ala Leu Leu Ala Gly Gln Arg His Leu 
465                 470                 475                 480 


Leu Thr Ala Gln Asp Glu Asn Gly Asp Thr Pro Leu His Leu Ala Ile 
                485                 490                 495     


Ile His Gly Gln Thr Ser Val Ile Glu Gln Ile Val Tyr Val Ile His 
            500                 505                 510         


His Ala Gln Asp Leu Gly Val Val Asn Leu Thr Asn His Leu His Gln 
        515                 520                 525             


Thr Pro Leu His Leu Ala Val Ile Thr Gly Gln Thr Ser Val Val Ser 
    530                 535                 540                 


Phe Leu Leu Arg Val Gly Ala Asp Pro Ala Leu Leu Asp Arg His Gly 
545                 550                 555                 560 


Asp Ser Ala Met His Leu Ala Leu Arg Ala Gly Ala Gly Ala Pro Glu 
                565                 570                 575     


Leu Leu Arg Ala Leu Leu Gln Ser Gly Ala Pro Ala Val Pro Gln Leu 
            580                 585                 590         


Leu His Met Pro Asp Phe Glu Gly Leu Tyr Pro Val His Leu Ala Val 
        595                 600                 605             


Arg Ala Arg Ser Pro Glu Cys Leu Asp Leu Leu Val Asp Ser Gly Ala 
    610                 615                 620                 


Glu Val Glu Ala Thr Glu Arg Gln Gly Gly Arg Thr Ala Leu His Leu 
625                 630                 635                 640 


Ala Thr Glu Met Glu Glu Leu Gly Leu Val Thr His Leu Val Thr Lys 
                645                 650                 655     


Leu Arg Ala Asn Val Asn Ala Arg Thr Phe Ala Gly Asn Thr Pro Leu 
            660                 665                 670         


His Leu Ala Ala Gly Leu Gly Tyr Pro Thr Leu Thr Arg Leu Leu Leu 
        675                 680                 685             


Lys Ala Gly Ala Asp Ile His Ala Glu Asn Glu Glu Pro Leu Cys Pro 
    690                 695                 700                 


Leu Pro Ser Pro Pro Thr Ser Asp Ser Asp Ser Asp Ser Glu Gly Pro 
705                 710                 715                 720 


Glu Lys Asp Thr Arg Ser Ser Phe Arg Gly His Thr Pro Leu Asp Leu 
                725                 730                 735     


Thr Cys Ser Thr Lys Val Lys Thr Leu Leu Leu Asn Ala Ala Gln Asn 
            740                 745                 750         


Thr Met Glu Pro Pro Leu Thr Pro Pro Ser Pro Ala Gly Pro Gly Leu 
        755                 760                 765             


Ser Leu Gly Asp Thr Ala Leu Gln Asn Leu Glu Gln Leu Leu Asp Gly 
    770                 775                 780                 


Pro Glu Ala Gln Gly Ser Trp Ala Glu Leu Ala Glu Arg Leu Gly Leu 
785                 790                 795                 800 


Arg Ser Leu Val Asp Thr Tyr Arg Gln Thr Thr Ser Pro Ser Gly Ser 
                805                 810                 815     


Leu Leu Arg Ser Tyr Glu Leu Ala Gly Gly Asp Leu Ala Gly Leu Leu 
            820                 825                 830         


Glu Ala Leu Ser Asp Met Gly Leu Glu Glu Gly Val Arg Leu Leu Arg 
        835                 840                 845             


Gly Pro Glu Thr Arg Asp Lys Leu Pro Ser Thr Glu Val Lys Glu Asp 
    850                 855                 860                 


Ser Ala Tyr Gly Ser Gln Ser Val Glu Gln Glu Ala Glu Lys Leu Gly 
865                 870                 875                 880 


Pro Pro Pro Glu Pro Pro Gly Gly Leu Cys His Gly His Pro Gln Pro 
                885                 890                 895     


Gln Val His 
            


<210>  3666
<211>  900
<212>  PRT
<213>  homo sapiens

<400>  3666

Met Glu Ser Cys Tyr Asn Pro Gly Leu Asp Gly Ile Ile Glu Tyr Asp 
1               5                   10                  15      


Asp Phe Lys Leu Asn Ser Ser Ile Val Glu Pro Lys Glu Pro Ala Pro 
            20                  25                  30          


Glu Thr Ala Asp Gly Pro Tyr Leu Val Ile Val Glu Gln Pro Lys Gln 
        35                  40                  45              


Arg Gly Phe Arg Phe Arg Tyr Gly Cys Glu Gly Pro Ser His Gly Gly 
    50                  55                  60                  


Leu Pro Gly Ala Ser Ser Glu Lys Gly Arg Lys Thr Tyr Pro Thr Val 
65                  70                  75                  80  


Lys Ile Cys Asn Tyr Glu Gly Pro Ala Lys Ile Glu Val Asp Leu Val 
                85                  90                  95      


Thr His Ser Asp Pro Pro Arg Ala His Ala His Ser Leu Val Gly Lys 
            100                 105                 110         


Gln Cys Ser Glu Leu Gly Ile Cys Ala Val Ser Val Gly Pro Lys Asp 
        115                 120                 125             


Met Thr Ala Gln Phe Asn Asn Leu Gly Val Leu His Val Thr Lys Lys 
    130                 135                 140                 


Asn Met Met Gly Thr Met Ile Gln Lys Leu Gln Arg Gln Arg Leu Arg 
145                 150                 155                 160 


Ser Arg Pro Gln Gly Leu Thr Glu Ala Glu Gln Arg Glu Leu Glu Gln 
                165                 170                 175     


Glu Ala Lys Glu Leu Lys Lys Val Met Asp Leu Ser Ile Val Arg Leu 
            180                 185                 190         


Arg Phe Ser Ala Phe Leu Arg Ala Ser Asp Gly Ser Phe Ser Leu Pro 
        195                 200                 205             


Leu Lys Pro Val Ile Ser Gln Pro Ile His Asp Ser Lys Ser Pro Gly 
    210                 215                 220                 


Ala Ser Asn Leu Lys Ile Ser Arg Met Asp Lys Thr Ala Gly Ser Val 
225                 230                 235                 240 


Arg Gly Gly Asp Glu Val Tyr Leu Leu Cys Asp Lys Val Gln Lys Asp 
                245                 250                 255     


Asp Ile Glu Val Arg Phe Tyr Glu Asp Asp Glu Asn Gly Trp Gln Ala 
            260                 265                 270         


Phe Gly Asp Phe Ser Pro Thr Asp Val His Lys Gln Tyr Ala Ile Val 
        275                 280                 285             


Phe Arg Thr Pro Pro Tyr His Lys Met Lys Ile Glu Arg Pro Val Thr 
    290                 295                 300                 


Val Phe Leu Gln Leu Lys Arg Lys Arg Gly Gly Asp Val Ser Asp Ser 
305                 310                 315                 320 


Lys Gln Phe Thr Tyr Tyr Pro Leu Val Glu Asp Lys Glu Glu Val Gln 
                325                 330                 335     


Arg Lys Arg Arg Lys Ala Leu Pro Thr Phe Ser Gln Pro Phe Gly Gly 
            340                 345                 350         


Gly Ser His Met Gly Gly Gly Ser Gly Gly Ala Ala Gly Gly Tyr Gly 
        355                 360                 365             


Gly Ala Gly Gly Gly Gly Ser Leu Gly Phe Phe Pro Ser Ser Leu Ala 
    370                 375                 380                 


Tyr Ser Pro Tyr Gln Ser Gly Ala Gly Pro Met Gly Cys Tyr Pro Gly 
385                 390                 395                 400 


Gly Gly Gly Gly Ala Gln Met Ala Ala Thr Val Pro Ser Arg Asp Ser 
                405                 410                 415     


Gly Glu Glu Ala Ala Glu Pro Ser Ala Pro Ser Arg Thr Pro Gln Cys 
            420                 425                 430         


Glu Pro Gln Ala Pro Glu Met Leu Gln Arg Ala Arg Glu Tyr Asn Ala 
        435                 440                 445             


Arg Leu Phe Gly Leu Ala Gln Arg Ser Ala Arg Ala Leu Leu Asp Tyr 
    450                 455                 460                 


Gly Val Thr Ala Asp Ala Arg Ala Leu Leu Ala Gly Gln Arg His Leu 
465                 470                 475                 480 


Leu Thr Ala Gln Asp Glu Asn Gly Asp Thr Pro Leu His Leu Ala Ile 
                485                 490                 495     


Ile His Gly Gln Thr Ser Val Ile Glu Gln Ile Val Tyr Val Ile His 
            500                 505                 510         


His Ala Gln Asp Leu Gly Val Val Asn Leu Thr Asn His Leu His Gln 
        515                 520                 525             


Thr Pro Leu His Leu Ala Val Ile Thr Gly Gln Thr Ser Val Val Ser 
    530                 535                 540                 


Phe Leu Leu Arg Val Gly Ala Asp Pro Ala Leu Leu Asp Arg His Gly 
545                 550                 555                 560 


Asp Ser Ala Met His Leu Ala Leu Arg Ala Gly Ala Gly Ala Pro Glu 
                565                 570                 575     


Leu Leu Arg Ala Leu Leu Gln Ser Gly Ala Pro Ala Val Pro Gln Leu 
            580                 585                 590         


Leu His Met Pro Asp Phe Glu Gly Leu Tyr Pro Val His Leu Ala Val 
        595                 600                 605             


Arg Ala Arg Ser Pro Glu Cys Leu Asp Leu Leu Val Asp Ser Gly Ala 
    610                 615                 620                 


Glu Val Glu Ala Thr Glu Arg Gln Gly Gly Arg Thr Ala Leu His Leu 
625                 630                 635                 640 


Ala Thr Glu Met Glu Glu Leu Gly Leu Val Thr His Leu Val Thr Lys 
                645                 650                 655     


Leu Arg Ala Asn Val Asn Ala Arg Thr Phe Ala Gly Asn Thr Pro Leu 
            660                 665                 670         


His Leu Ala Ala Gly Leu Gly Tyr Pro Thr Leu Thr Arg Leu Leu Leu 
        675                 680                 685             


Lys Ala Gly Ala Asp Ile His Ala Glu Asn Glu Glu Pro Leu Cys Pro 
    690                 695                 700                 


Leu Pro Ser Pro Pro Thr Ser Asp Ser Asp Ser Asp Ser Glu Gly Pro 
705                 710                 715                 720 


Glu Lys Asp Thr Arg Ser Ser Phe Arg Gly His Thr Pro Leu Asp Leu 
                725                 730                 735     


Thr Cys Ser Thr Lys Val Lys Thr Leu Leu Leu Asn Ala Ala Gln Asn 
            740                 745                 750         


Thr Met Glu Pro Pro Leu Thr Pro Pro Ser Pro Ala Gly Pro Gly Leu 
        755                 760                 765             


Ser Leu Gly Asp Thr Ala Leu Gln Asn Leu Glu Gln Leu Leu Asp Gly 
    770                 775                 780                 


Pro Glu Ala Gln Gly Ser Trp Ala Glu Leu Ala Glu Arg Leu Gly Leu 
785                 790                 795                 800 


Arg Ser Leu Val Asp Thr Tyr Arg Gln Thr Thr Ser Pro Ser Gly Ser 
                805                 810                 815     


Leu Leu Arg Ser Tyr Glu Leu Ala Gly Gly Asp Leu Ala Gly Leu Leu 
            820                 825                 830         


Glu Ala Leu Ser Asp Met Gly Leu Glu Glu Gly Val Arg Leu Leu Arg 
        835                 840                 845             


Gly Pro Glu Thr Arg Asp Lys Leu Pro Ser Thr Ala Glu Val Lys Glu 
    850                 855                 860                 


Asp Ser Ala Tyr Gly Ser Gln Ser Val Glu Gln Glu Ala Glu Lys Leu 
865                 870                 875                 880 


Gly Pro Pro Pro Glu Pro Pro Gly Gly Leu Cys His Gly His Pro Gln 
                885                 890                 895     


Pro Gln Val His 
            900 


<210>  3667
<211>  347
<212>  PRT
<213>  homo sapiens

<400>  3667

Met Glu Gln Tyr Thr Ala Asn Ser Asn Ser Ser Thr Glu Gln Ile Val 
1               5                   10                  15      


Val Gln Ala Gly Gln Ile Gln Gln Gln Gln Gln Gly Gly Val Thr Ala 
            20                  25                  30          


Val Gln Leu Gln Thr Glu Ala Gln Val Ala Ser Ala Ser Gly Gln Gln 
        35                  40                  45              


Val Gln Thr Leu Gln Val Val Gln Gly Gln Pro Leu Met Val Gln Val 
    50                  55                  60                  


Ser Gly Gly Gln Leu Ile Thr Ser Thr Gly Gln Pro Ile Met Val Gln 
65                  70                  75                  80  


Ala Val Pro Gly Gly Gln Gly Gln Thr Ile Met Gln Val Pro Val Ser 
                85                  90                  95      


Gly Thr Gln Gly Leu Gln Gln Ile Gln Leu Val Pro Pro Gly Gln Ile 
            100                 105                 110         


Gln Ile Gln Gly Gly Gln Ala Val Gln Val Gln Gly Gln Gln Gly Gln 
        115                 120                 125             


Thr Gln Gln Ile Ile Ile Gln Gln Pro Gln Thr Ala Val Thr Ala Gly 
    130                 135                 140                 


Gln Thr Gln Thr Gln Gln Gln Ile Ala Val Gln Gly Gln Gln Val Ala 
145                 150                 155                 160 


Gln Thr Ala Glu Gly Gln Thr Ile Val Tyr Gln Pro Val Asn Ala Asp 
                165                 170                 175     


Gly Thr Ile Leu Gln Gln Val Thr Val Pro Val Ser Gly Met Ile Thr 
            180                 185                 190         


Ile Pro Ala Ala Ser Leu Ala Gly Ala Gln Ile Val Gln Thr Gly Ala 
        195                 200                 205             


Asn Thr Asn Thr Thr Ser Ser Gly Gln Gly Thr Val Thr Val Thr Leu 
    210                 215                 220                 


Pro Val Ala Gly Asn Val Val Asn Ser Gly Gly Met Val Met Met Val 
225                 230                 235                 240 


Pro Gly Ala Gly Ser Val Pro Ala Ile Gln Arg Ile Pro Leu Pro Gly 
                245                 250                 255     


Ala Glu Met Leu Glu Glu Glu Pro Leu Tyr Val Asn Ala Lys Gln Tyr 
            260                 265                 270         


His Arg Ile Leu Lys Arg Arg Gln Ala Arg Ala Lys Leu Glu Ala Glu 
        275                 280                 285             


Gly Lys Ile Pro Lys Glu Arg Arg Lys Tyr Leu His Glu Ser Arg His 
    290                 295                 300                 


Arg His Ala Met Ala Arg Lys Arg Gly Glu Gly Gly Arg Phe Phe Ser 
305                 310                 315                 320 


Pro Lys Glu Lys Asp Ser Pro His Met Gln Asp Pro Asn Gln Ala Asp 
                325                 330                 335     


Glu Glu Ala Met Thr Gln Ile Ile Arg Val Ser 
            340                 345         


<210>  3668
<211>  318
<212>  PRT
<213>  homo sapiens

<400>  3668

Met Glu Gln Tyr Thr Ala Asn Ser Asn Ser Ser Thr Glu Gln Ile Val 
1               5                   10                  15      


Val Gln Ala Gly Gln Ile Gln Gln Gln Val Gln Gly Gln Pro Leu Met 
            20                  25                  30          


Val Gln Val Ser Gly Gly Gln Leu Ile Thr Ser Thr Gly Gln Pro Ile 
        35                  40                  45              


Met Val Gln Ala Val Pro Gly Gly Gln Gly Gln Thr Ile Met Gln Val 
    50                  55                  60                  


Pro Val Ser Gly Thr Gln Gly Leu Gln Gln Ile Gln Leu Val Pro Pro 
65                  70                  75                  80  


Gly Gln Ile Gln Ile Gln Gly Gly Gln Ala Val Gln Val Gln Gly Gln 
                85                  90                  95      


Gln Gly Gln Thr Gln Gln Ile Ile Ile Gln Gln Pro Gln Thr Ala Val 
            100                 105                 110         


Thr Ala Gly Gln Thr Gln Thr Gln Gln Gln Ile Ala Val Gln Gly Gln 
        115                 120                 125             


Gln Val Ala Gln Thr Ala Glu Gly Gln Thr Ile Val Tyr Gln Pro Val 
    130                 135                 140                 


Asn Ala Asp Gly Thr Ile Leu Gln Gln Val Thr Val Pro Val Ser Gly 
145                 150                 155                 160 


Met Ile Thr Ile Pro Ala Ala Ser Leu Ala Gly Ala Gln Ile Val Gln 
                165                 170                 175     


Thr Gly Ala Asn Thr Asn Thr Thr Ser Ser Gly Gln Gly Thr Val Thr 
            180                 185                 190         


Val Thr Leu Pro Val Ala Gly Asn Val Val Asn Ser Gly Gly Met Val 
        195                 200                 205             


Met Met Val Pro Gly Ala Gly Ser Val Pro Ala Ile Gln Arg Ile Pro 
    210                 215                 220                 


Leu Pro Gly Ala Glu Met Leu Glu Glu Glu Pro Leu Tyr Val Asn Ala 
225                 230                 235                 240 


Lys Gln Tyr His Arg Ile Leu Lys Arg Arg Gln Ala Arg Ala Lys Leu 
                245                 250                 255     


Glu Ala Glu Gly Lys Ile Pro Lys Glu Arg Arg Lys Tyr Leu His Glu 
            260                 265                 270         


Ser Arg His Arg His Ala Met Ala Arg Lys Arg Gly Glu Gly Gly Arg 
        275                 280                 285             


Phe Phe Ser Pro Lys Glu Lys Asp Ser Pro His Met Gln Asp Pro Asn 
    290                 295                 300                 


Gln Ala Asp Glu Glu Ala Met Thr Gln Ile Ile Arg Val Ser 
305                 310                 315             


<210>  3669
<211>  335
<212>  PRT
<213>  homo sapiens

<400>  3669

Met Ser Thr Glu Gly Gly Phe Gly Gly Thr Ser Ser Ser Asp Ala Gln 
1               5                   10                  15      


Gln Ser Leu Gln Ser Phe Trp Pro Arg Val Met Glu Glu Ile Arg Asn 
            20                  25                  30          


Leu Thr Val Lys Asp Phe Arg Val Gln Glu Leu Pro Leu Ala Arg Ile 
        35                  40                  45              


Lys Lys Ile Met Lys Leu Asp Glu Asp Val Lys Met Ile Ser Ala Glu 
    50                  55                  60                  


Ala Pro Val Leu Phe Ala Lys Ala Ala Gln Ile Phe Ile Thr Glu Leu 
65                  70                  75                  80  


Thr Leu Arg Ala Trp Ile His Thr Glu Asp Asn Lys Arg Arg Thr Leu 
                85                  90                  95      


Gln Arg Asn Asp Ile Ala Met Ala Ile Thr Lys Phe Asp Gln Phe Asp 
            100                 105                 110         


Phe Leu Ile Asp Ile Val Pro Arg Asp Glu Leu Lys Pro Pro Lys Arg 
        115                 120                 125             


Gln Glu Glu Val Arg Gln Ser Val Thr Pro Ala Glu Pro Val Gln Tyr 
    130                 135                 140                 


Tyr Phe Thr Leu Ala Gln Gln Pro Thr Ala Val Gln Val Gln Gly Gln 
145                 150                 155                 160 


Gln Gln Gly Gln Gln Thr Thr Ser Ser Thr Thr Thr Ile Gln Pro Gly 
                165                 170                 175     


Gln Ile Ile Ile Ala Gln Pro Gln Gln Gly Gln Thr Thr Pro Val Thr 
            180                 185                 190         


Met Gln Val Gly Glu Gly Gln Gln Val Gln Ile Val Gln Ala Gln Pro 
        195                 200                 205             


Gln Gly Gln Ala Gln Gln Ala Gln Ser Gly Thr Gly Gln Thr Met Gln 
    210                 215                 220                 


Val Met Gln Gln Ile Ile Thr Asn Thr Gly Glu Ile Gln Gln Ile Pro 
225                 230                 235                 240 


Val Gln Leu Asn Ala Gly Gln Leu Gln Tyr Ile Arg Leu Ala Gln Pro 
                245                 250                 255     


Val Ser Gly Thr Gln Val Val Gln Gly Gln Ile Gln Thr Leu Ala Thr 
            260                 265                 270         


Asn Ala Gln Gln Ile Thr Gln Thr Glu Val Gln Gln Gly Gln Gln Gln 
        275                 280                 285             


Phe Ser Gln Phe Thr Asp Gly Gln Gln Leu Tyr Gln Ile Gln Gln Val 
    290                 295                 300                 


Thr Met Pro Ala Gly Gln Asp Leu Ala Gln Pro Met Phe Ile Gln Ser 
305                 310                 315                 320 


Ala Asn Gln Pro Ser Asp Gly Gln Ala Pro Gln Val Thr Gly Asp 
                325                 330                 335 


<210>  3670
<211>  334
<212>  PRT
<213>  homo sapiens

<400>  3670

Met Ser Thr Glu Gly Gly Phe Gly Gly Thr Ser Ser Ser Asp Ala Gln 
1               5                   10                  15      


Gln Ser Leu Gln Ser Phe Trp Pro Arg Val Met Glu Glu Ile Arg Asn 
            20                  25                  30          


Leu Thr Val Lys Asp Phe Arg Val Gln Glu Leu Pro Leu Ala Arg Ile 
        35                  40                  45              


Lys Lys Ile Met Lys Leu Asp Glu Asp Val Lys Met Ile Ser Ala Glu 
    50                  55                  60                  


Ala Pro Val Leu Phe Ala Lys Ala Ala Gln Ile Phe Ile Thr Glu Leu 
65                  70                  75                  80  


Thr Leu Arg Ala Trp Ile His Thr Glu Asp Asn Lys Arg Arg Thr Leu 
                85                  90                  95      


Gln Arg Asn Asp Ile Ala Met Ala Ile Thr Lys Phe Asp Gln Phe Asp 
            100                 105                 110         


Phe Leu Ile Asp Ile Val Pro Arg Asp Glu Leu Lys Pro Pro Lys Arg 
        115                 120                 125             


Gln Glu Glu Val Arg Gln Ser Val Thr Pro Ala Glu Pro Val Gln Tyr 
    130                 135                 140                 


Tyr Phe Thr Leu Ala Gln Gln Pro Thr Ala Val Gln Val Gln Gly Gln 
145                 150                 155                 160 


Gln Gln Gly Gln Gln Thr Thr Ser Ser Thr Thr Thr Ile Gln Pro Gly 
                165                 170                 175     


Gln Ile Ile Ile Ala Gln Pro Gln Gln Gly Gln Thr Thr Pro Val Thr 
            180                 185                 190         


Met Gln Val Gly Glu Gly Gln Gln Val Gln Ile Val Gln Ala Gln Pro 
        195                 200                 205             


Gln Gly Gln Ala Gln Gln Ala Gln Ser Gly Thr Gly Gln Thr Met Gln 
    210                 215                 220                 


Val Met Gln Gln Ile Ile Thr Asn Thr Gly Glu Ile Gln Gln Ile Pro 
225                 230                 235                 240 


Val Gln Leu Asn Ala Gly Gln Leu Gln Tyr Ile Arg Leu Ala Gln Pro 
                245                 250                 255     


Val Ser Gly Thr Gln Val Val Gln Gly Gln Ile Gln Thr Leu Ala Thr 
            260                 265                 270         


Asn Ala Gln Gln Ile Thr Gln Thr Glu Val Gln Gln Gly Gln Gln Gln 
        275                 280                 285             


Phe Ser Gln Phe Thr Asp Gly Gln Leu Tyr Gln Ile Gln Gln Val Thr 
    290                 295                 300                 


Met Pro Ala Gly Gln Asp Leu Ala Gln Pro Met Phe Ile Gln Ser Ala 
305                 310                 315                 320 


Asn Gln Pro Ser Asp Gly Gln Ala Pro Gln Val Thr Gly Asp 
                325                 330                 


<210>  3671
<211>  614
<212>  PRT
<213>  homo sapiens

<400>  3671

Met Asn Lys Leu Asn Phe His Asn Asn Arg Val Met Gln Asp Arg Arg 
1               5                   10                  15      


Ser Val Cys Ile Phe Leu Pro Asn Asp Glu Ser Leu Asn Ile Ile Ile 
            20                  25                  30          


Asn Val Lys Ile Leu Cys His Gln Leu Leu Val Gln Val Cys Asp Leu 
        35                  40                  45              


Leu Arg Leu Lys Asp Cys His Leu Phe Gly Leu Ser Val Ile Gln Asn 
    50                  55                  60                  


Asn Glu His Val Tyr Met Glu Leu Ser Gln Lys Leu Tyr Lys Tyr Cys 
65                  70                  75                  80  


Pro Lys Glu Trp Lys Lys Glu Ala Ser Lys Gly Ile Asp Gln Phe Gly 
                85                  90                  95      


Pro Pro Met Ile Ile His Phe Arg Val Gln Tyr Tyr Val Glu Asn Gly 
            100                 105                 110         


Arg Leu Ile Ser Asp Arg Ala Ala Arg Tyr Tyr Tyr Tyr Trp His Leu 
        115                 120                 125             


Arg Lys Gln Val Leu His Ser Gln Cys Val Leu Arg Glu Glu Ala Tyr 
    130                 135                 140                 


Phe Leu Leu Ala Ala Phe Ala Leu Gln Ala Asp Leu Gly Asn Phe Lys 
145                 150                 155                 160 


Arg Asn Lys His Tyr Gly Lys Tyr Phe Glu Pro Glu Ala Tyr Phe Pro 
                165                 170                 175     


Ser Trp Val Val Ser Lys Arg Gly Lys Asp Tyr Ile Leu Lys His Ile 
            180                 185                 190         


Pro Asn Met His Lys Asp Gln Phe Ala Leu Thr Ala Ser Glu Ala His 
        195                 200                 205             


Leu Lys Tyr Ile Lys Glu Ala Val Arg Leu Asp Asp Val Ala Val His 
    210                 215                 220                 


Tyr Tyr Arg Leu Tyr Lys Asp Lys Arg Glu Ile Glu Ala Ser Leu Thr 
225                 230                 235                 240 


Leu Gly Leu Thr Met Arg Gly Ile Gln Ile Phe Gln Asn Leu Asp Glu 
                245                 250                 255     


Glu Lys Gln Leu Leu Tyr Asp Phe Pro Trp Thr Asn Val Gly Lys Leu 
            260                 265                 270         


Val Phe Val Gly Lys Lys Phe Glu Ile Leu Pro Asp Gly Leu Pro Ser 
        275                 280                 285             


Ala Arg Lys Leu Ile Tyr Tyr Thr Gly Cys Pro Met Arg Ser Arg His 
    290                 295                 300                 


Leu Leu Gln Leu Leu Ser Asn Ser His Arg Leu Tyr Met Asn Leu Gln 
305                 310                 315                 320 


Pro Val Leu Arg His Ile Arg Lys Leu Glu Glu Asn Glu Glu Lys Lys 
                325                 330                 335     


Gln Tyr Arg Glu Ser Tyr Ile Ser Asp Asn Leu Asp Leu Asp Met Asp 
            340                 345                 350         


Gln Leu Glu Lys Arg Ser Arg Ala Ser Gly Ser Ser Ala Gly Ser Met 
        355                 360                 365             


Lys His Lys Arg Leu Ser Arg His Ser Thr Ala Ser His Ser Ser Ser 
    370                 375                 380                 


His Thr Ser Gly Ile Glu Ala Asp Thr Lys Pro Arg Asp Thr Gly Pro 
385                 390                 395                 400 


Glu Asp Ser Tyr Ser Ser Ser Ala Ile His Arg Lys Leu Lys Thr Cys 
                405                 410                 415     


Ser Ser Met Thr Ser His Gly Ser Ser His Thr Ser Gly Val Glu Ser 
            420                 425                 430         


Gly Gly Lys Asp Arg Leu Glu Glu Asp Leu Gln Asp Asp Glu Ile Glu 
        435                 440                 445             


Met Leu Val Asp Asp Pro Arg Asp Leu Glu Gln Met Asn Glu Glu Ser 
    450                 455                 460                 


Leu Glu Val Ser Pro Asp Met Cys Ile Tyr Ile Thr Glu Asp Met Leu 
465                 470                 475                 480 


Met Ser Arg Lys Leu Asn Gly His Ser Gly Leu Ile Val Lys Glu Ile 
                485                 490                 495     


Gly Ser Ser Thr Ser Ser Ser Ser Glu Thr Val Val Lys Leu Arg Gly 
            500                 505                 510         


Gln Ser Thr Asp Ser Leu Pro Gln Thr Ile Cys Arg Lys Pro Lys Thr 
        515                 520                 525             


Ser Thr Asp Arg His Ser Leu Ser Leu Asp Asp Ile Arg Leu Tyr Gln 
    530                 535                 540                 


Lys Asp Phe Leu Arg Ile Ala Gly Leu Cys Gln Asp Thr Ala Gln Ser 
545                 550                 555                 560 


Tyr Thr Phe Gly Cys Gly His Glu Leu Asp Glu Glu Gly Leu Tyr Cys 
                565                 570                 575     


Asn Ser Cys Leu Ala Gln Gln Cys Ile Asn Ile Gln Asp Ala Phe Pro 
            580                 585                 590         


Val Lys Arg Thr Ser Lys Tyr Phe Ser Leu Asp Leu Thr His Asp Glu 
        595                 600                 605             


Val Pro Glu Phe Val Val 
    610                 


<210>  3672
<211>  776
<212>  PRT
<213>  homo sapiens

<400>  3672

Met Ser Glu Ala Val Arg Val Pro Ser Pro Ala Thr Pro Leu Val Val 
1               5                   10                  15      


Ala Ala Ala Ala Pro Glu Glu Arg Lys Gly Lys Glu Ser Glu Arg Glu 
            20                  25                  30          


Lys Leu Pro Pro Ile Val Ser Ala Gly Ala Gly Ala Thr Ala Gly Leu 
        35                  40                  45              


Asp Arg Gly Ala Lys Gly Gln Ile Ser Thr Phe Ser Ser Phe Ile Ser 
    50                  55                  60                  


Ala Val Ser Pro Lys Lys Glu Ala Ala Glu Asn Arg Ser Ser Pro Ala 
65                  70                  75                  80  


His Leu Val Phe Pro Asn Ile Lys Asn Val Arg Glu Pro Pro Pro Ile 
                85                  90                  95      


Cys Leu Asp Val Arg Gln Lys Gln Arg Thr Ser Met Asp Ala Ser Ser 
            100                 105                 110         


Ser Glu Met Lys Ala Pro Val Leu Pro Glu Pro Ile Leu Pro Ile Gln 
        115                 120                 125             


Pro Lys Thr Val Lys Asp Phe Gln Glu Asp Val Glu Lys Val Lys Ser 
    130                 135                 140                 


Ser Gly Asp Trp Lys Ala Val His Asp Phe Tyr Leu Thr Thr Phe Asp 
145                 150                 155                 160 


Ser Phe Pro Glu Leu Asn Ala Ala Phe Lys Lys Asp Ala Thr Ala Ser 
                165                 170                 175     


Phe Asn Thr Ile Glu Asp Ser Gly Ile Asn Ala Lys Phe Val Asn Ala 
            180                 185                 190         


Val Tyr Asp Thr Leu Leu Asn Thr Pro Gln Asp Val Gln Lys Thr Val 
        195                 200                 205             


Leu Lys Gly Ile Ile Asn Ser Leu Leu Arg Glu Trp Lys Gly Pro Arg 
    210                 215                 220                 


Thr Lys Asp Asp Leu Arg Ala Tyr Phe Ile Leu Leu Gln Asn Pro Gln 
225                 230                 235                 240 


Phe Asn Asn Thr Ser Thr Tyr Val Ile Tyr Ala His Leu Leu Arg Gln 
                245                 250                 255     


Ile Ala Thr Leu Val Glu Ala Asp His His Phe Leu Val His Trp Phe 
            260                 265                 270         


Lys Lys Leu Ser Gln Lys Arg Phe Lys Gln Leu Val Glu Arg Leu Leu 
        275                 280                 285             


Gln Phe Ile Ser Leu Arg Leu Phe Pro Ala Lys Pro Glu Glu Phe Pro 
    290                 295                 300                 


Pro Ile Thr Lys Cys Ser Trp Trp Ile Pro Ser Ala Ala Lys Val Leu 
305                 310                 315                 320 


Ala Leu Leu Asn Thr Ala Asn Asn Leu Val His Pro Pro Leu Ile Pro 
                325                 330                 335     


Tyr Thr Asp Phe Tyr Asn Ser Thr Leu Asp His Ile Asp Leu Met Glu 
            340                 345                 350         


Glu Tyr His Thr Trp Gln Asn Phe Gly Asn Ser His Arg Phe Ser Phe 
        355                 360                 365             


Cys Gln Tyr Pro Phe Val Ile Ser Val Ala Ala Lys Lys Ile Ile Ile 
    370                 375                 380                 


Gln Arg Asp Ser Glu Gln Gln Met Ile Asn Ile Ala Arg Gln Ser Leu 
385                 390                 395                 400 


Val Asp Lys Val Ser Arg Arg Gln Arg Pro Asp Met Asn Ile Leu Phe 
                405                 410                 415     


Leu Asn Met Lys Val Arg Arg Thr His Leu Val Ser Asp Ser Leu Asp 
            420                 425                 430         


Glu Leu Thr Arg Lys Arg Ala Asp Leu Lys Lys Lys Leu Lys Val Thr 
        435                 440                 445             


Phe Val Gly Glu Ala Gly Leu Asp Met Gly Gly Leu Thr Lys Glu Trp 
    450                 455                 460                 


Phe Leu Leu Leu Ile Arg Gln Ile Phe His Pro Asp Tyr Gly Met Phe 
465                 470                 475                 480 


Thr Tyr His Lys Asp Ser His Cys His Trp Phe Ser Ser Phe Lys Cys 
                485                 490                 495     


Asp Asn Tyr Ser Glu Phe Arg Leu Val Gly Ile Leu Met Gly Leu Ala 
            500                 505                 510         


Val Tyr Asn Ser Ile Thr Leu Asp Ile Arg Phe Pro Pro Cys Cys Tyr 
        515                 520                 525             


Lys Lys Leu Leu Ser Pro Pro Ile Ile Pro Ser Asp Gln Asn Ile Pro 
    530                 535                 540                 


Val Gly Ile Cys Asn Val Thr Val Asp Asp Leu Cys Gln Ile Met Pro 
545                 550                 555                 560 


Glu Leu Ala His Gly Leu Ser Glu Leu Leu Ser His Glu Gly Asn Val 
                565                 570                 575     


Glu Glu Asp Phe Tyr Ser Thr Phe Gln Val Phe Gln Glu Glu Phe Gly 
            580                 585                 590         


Ile Ile Lys Ser Tyr Asn Leu Lys Pro Gly Gly Asp Lys Ile Ser Val 
        595                 600                 605             


Thr Asn Gln Asn Arg Lys Glu Tyr Val Gln Leu Tyr Thr Asp Phe Leu 
    610                 615                 620                 


Leu Asn Lys Ser Ile Tyr Lys Gln Phe Ala Ala Phe Tyr Tyr Gly Phe 
625                 630                 635                 640 


His Ser Val Cys Ala Ser Asn Ala Leu Met Leu Leu Arg Pro Glu Glu 
                645                 650                 655     


Val Glu Ile Leu Val Cys Gly Ser Pro Asp Leu Asp Met His Ala Leu 
            660                 665                 670         


Gln Arg Ser Thr Gln Tyr Asp Gly Tyr Ala Lys Thr Asp Leu Thr Ile 
        675                 680                 685             


Lys Tyr Phe Trp Asp Val Val Leu Gly Phe Pro Leu Asp Leu Gln Lys 
    690                 695                 700                 


Lys Leu Leu His Phe Thr Thr Gly Ser Asp Arg Val Pro Val Gly Gly 
705                 710                 715                 720 


Met Ala Asp Leu Asn Phe Lys Ile Ser Lys Asn Glu Thr Ser Thr Asn 
                725                 730                 735     


Cys Leu Pro Val Ala His Thr Cys Phe Asn Gln Leu Cys Leu Pro Pro 
            740                 745                 750         


Tyr Lys Ser Lys Lys Asp Leu Lys Gln Lys Leu Ile Ile Gly Ile Ser 
        755                 760                 765             


Asn Ser Glu Gly Phe Gly Leu Glu 
    770                 775     


<210>  3673
<211>  267
<212>  PRT
<213>  homo sapiens

<400>  3673

Met Gly Ser Ala Cys Ile Lys Val Thr Lys Tyr Phe Leu Phe Leu Phe 
1               5                   10                  15      


Asn Leu Ile Phe Phe Ile Leu Gly Ala Val Ile Leu Gly Phe Gly Val 
            20                  25                  30          


Trp Ile Leu Ala Asp Lys Ser Ser Phe Ile Ser Val Leu Gln Thr Ser 
        35                  40                  45              


Ser Ser Ser Leu Arg Met Gly Ala Tyr Val Phe Ile Gly Val Gly Ala 
    50                  55                  60                  


Val Thr Met Leu Met Gly Phe Leu Gly Cys Ile Gly Ala Val Asn Glu 
65                  70                  75                  80  


Val Arg Cys Leu Leu Gly Leu Tyr Phe Ala Phe Leu Leu Leu Ile Leu 
                85                  90                  95      


Ile Ala Gln Val Thr Ala Gly Ala Leu Phe Tyr Phe Asn Met Gly Lys 
            100                 105                 110         


Leu Lys Gln Glu Met Gly Gly Ile Val Thr Glu Leu Ile Arg Asp Tyr 
        115                 120                 125             


Asn Ser Ser Arg Glu Asp Ser Leu Gln Asp Ala Trp Asp Tyr Val Gln 
    130                 135                 140                 


Ala Gln Val Lys Cys Cys Gly Trp Val Ser Phe Tyr Asn Trp Thr Asp 
145                 150                 155                 160 


Asn Ala Glu Leu Met Asn Arg Pro Glu Val Thr Tyr Pro Cys Ser Cys 
                165                 170                 175     


Glu Val Lys Gly Glu Glu Asp Asn Ser Leu Ser Val Arg Lys Gly Phe 
            180                 185                 190         


Cys Glu Ala Pro Gly Asn Arg Thr Gln Ser Gly Asn His Pro Glu Asp 
        195                 200                 205             


Trp Pro Val Tyr Gln Glu Gly Cys Met Glu Lys Val Gln Ala Trp Leu 
    210                 215                 220                 


Gln Glu Asn Leu Gly Ile Ile Leu Gly Val Gly Val Gly Val Ala Ile 
225                 230                 235                 240 


Ile Glu Leu Leu Gly Met Val Leu Ser Ile Cys Leu Cys Arg His Val 
                245                 250                 255     


His Ser Glu Asp Tyr Ser Lys Val Pro Lys Tyr 
            260                 265         


<210>  3674
<211>  454
<212>  PRT
<213>  homo sapiens

<400>  3674

Met Asp Phe Phe Arg Val Val Glu Asn Gln Gln Pro Pro Ala Thr Met 
1               5                   10                  15      


Pro Leu Asn Val Ser Phe Thr Asn Arg Asn Tyr Asp Leu Asp Tyr Asp 
            20                  25                  30          


Ser Val Gln Pro Tyr Phe Tyr Cys Asp Glu Glu Glu Asn Phe Tyr Gln 
        35                  40                  45              


Gln Gln Gln Gln Ser Glu Leu Gln Pro Pro Ala Pro Ser Glu Asp Ile 
    50                  55                  60                  


Trp Lys Lys Phe Glu Leu Leu Pro Thr Pro Pro Leu Ser Pro Ser Arg 
65                  70                  75                  80  


Arg Ser Gly Leu Cys Ser Pro Ser Tyr Val Ala Val Thr Pro Phe Ser 
                85                  90                  95      


Leu Arg Gly Asp Asn Asp Gly Gly Gly Gly Ser Phe Ser Thr Ala Asp 
            100                 105                 110         


Gln Leu Glu Met Val Thr Glu Leu Leu Gly Gly Asp Met Val Asn Gln 
        115                 120                 125             


Ser Phe Ile Cys Asp Pro Asp Asp Glu Thr Phe Ile Lys Asn Ile Ile 
    130                 135                 140                 


Ile Gln Asp Cys Met Trp Ser Gly Phe Ser Ala Ala Ala Lys Leu Val 
145                 150                 155                 160 


Ser Glu Lys Leu Ala Ser Tyr Gln Ala Ala Arg Lys Asp Ser Gly Ser 
                165                 170                 175     


Pro Asn Pro Ala Arg Gly His Ser Val Cys Ser Thr Ser Ser Leu Tyr 
            180                 185                 190         


Leu Gln Asp Leu Ser Ala Ala Ala Ser Glu Cys Ile Asp Pro Ser Val 
        195                 200                 205             


Val Phe Pro Tyr Pro Leu Asn Asp Ser Ser Ser Pro Lys Ser Cys Ala 
    210                 215                 220                 


Ser Gln Asp Ser Ser Ala Phe Ser Pro Ser Ser Asp Ser Leu Leu Ser 
225                 230                 235                 240 


Ser Thr Glu Ser Ser Pro Gln Gly Ser Pro Glu Pro Leu Val Leu His 
                245                 250                 255     


Glu Glu Thr Pro Pro Thr Thr Ser Ser Asp Ser Glu Glu Glu Gln Glu 
            260                 265                 270         


Asp Glu Glu Glu Ile Asp Val Val Ser Val Glu Lys Arg Gln Ala Pro 
        275                 280                 285             


Gly Lys Arg Ser Glu Ser Gly Ser Pro Ser Ala Gly Gly His Ser Lys 
    290                 295                 300                 


Pro Pro His Ser Pro Leu Val Leu Lys Arg Cys His Val Ser Thr His 
305                 310                 315                 320 


Gln His Asn Tyr Ala Ala Pro Pro Ser Thr Arg Lys Asp Tyr Pro Ala 
                325                 330                 335     


Ala Lys Arg Val Lys Leu Asp Ser Val Arg Val Leu Arg Gln Ile Ser 
            340                 345                 350         


Asn Asn Arg Lys Cys Thr Ser Pro Arg Ser Ser Asp Thr Glu Glu Asn 
        355                 360                 365             


Val Lys Arg Arg Thr His Asn Val Leu Glu Arg Gln Arg Arg Asn Glu 
    370                 375                 380                 


Leu Lys Arg Ser Phe Phe Ala Leu Arg Asp Gln Ile Pro Glu Leu Glu 
385                 390                 395                 400 


Asn Asn Glu Lys Ala Pro Lys Val Val Ile Leu Lys Lys Ala Thr Ala 
                405                 410                 415     


Tyr Ile Leu Ser Val Gln Ala Glu Glu Gln Lys Leu Ile Ser Glu Glu 
            420                 425                 430         


Asp Leu Leu Arg Lys Arg Arg Glu Gln Leu Lys His Lys Leu Glu Gln 
        435                 440                 445             


Leu Arg Asn Ser Cys Ala 
    450                 


<210>  3675
<211>  172
<212>  PRT
<213>  homo sapiens

<400>  3675

Met Ser Ser Lys Arg Ala Lys Ala Lys Thr Thr Lys Lys Arg Pro Gln 
1               5                   10                  15      


Arg Ala Thr Ser Asn Val Phe Ala Met Phe Asp Gln Ser Gln Ile Gln 
            20                  25                  30          


Glu Phe Lys Glu Ala Phe Asn Met Ile Asp Gln Asn Arg Asp Gly Phe 
        35                  40                  45              


Ile Asp Lys Glu Asp Leu His Asp Met Leu Ala Ser Leu Gly Lys Asn 
    50                  55                  60                  


Pro Thr Asp Glu Tyr Leu Glu Gly Met Met Ser Glu Ala Pro Gly Pro 
65                  70                  75                  80  


Ile Asn Phe Thr Met Phe Leu Thr Met Phe Gly Glu Lys Leu Asn Gly 
                85                  90                  95      


Thr Asp Pro Glu Asp Val Ile Arg Asn Ala Phe Ala Cys Phe Asp Glu 
            100                 105                 110         


Glu Ala Ser Gly Phe Ile His Glu Asp His Leu Arg Glu Leu Leu Thr 
        115                 120                 125             


Thr Met Gly Asp Arg Phe Thr Asp Glu Glu Val Asp Glu Met Tyr Arg 
    130                 135                 140                 


Glu Ala Pro Ile Asp Lys Lys Gly Asn Phe Asn Tyr Val Glu Phe Thr 
145                 150                 155                 160 


Arg Ile Leu Lys His Gly Ala Lys Asp Lys Asp Asp 
                165                 170         


<210>  3676
<211>  727
<212>  PRT
<213>  homo sapiens

<400>  3676

Met Asn Gln Lys Leu Leu Lys Leu Glu Asn Leu Leu Arg Phe His Thr 
1               5                   10                  15      


Ile Tyr Arg Gln Leu His Ser Leu Cys Gln Arg Arg Ala Leu Arg Gln 
            20                  25                  30          


Trp Arg His Gly Phe Ser Ser Ala Tyr Pro Val Trp Thr Ala Gln Leu 
        35                  40                  45              


Cys Ala Trp Pro Trp Pro Thr Asp Val Leu Thr Gly Ala Ala Leu Ser 
    50                  55                  60                  


Gln Tyr Arg Leu Leu Val Thr Lys Lys Glu Glu Gly Pro Trp Lys Ser 
65                  70                  75                  80  


Gln Leu Ser Ser Thr Lys Ser Lys Lys Val Val Glu Val Trp Ile Gly 
                85                  90                  95      


Met Thr Ile Glu Glu Leu Ala Arg Ala Met Glu Lys Asn Thr Asp Tyr 
            100                 105                 110         


Val Tyr Glu Ala Leu Leu Asn Thr Asp Ile Asp Ile Asp Ser Leu Glu 
        115                 120                 125             


Ala Asp Ser His Leu Asp Glu Val Trp Ile Lys Glu Val Ile Thr Lys 
    130                 135                 140                 


Ala Gly Met Lys Leu Lys Trp Ser Lys Leu Lys Gln Asp Lys Val Arg 
145                 150                 155                 160 


Lys Asn Lys Asp Ala Val Arg Arg Pro Gln Ala Asp Pro Ala Leu Leu 
                165                 170                 175     


Thr Pro Arg Ser Pro Val Val Thr Ile Met Gly His Val Asp His Gly 
            180                 185                 190         


Lys Thr Thr Leu Leu Asp Lys Phe Arg Lys Thr Gln Val Ala Ala Val 
        195                 200                 205             


Glu Thr Gly Gly Ile Thr Gln His Ile Gly Ala Phe Leu Val Ser Leu 
    210                 215                 220                 


Pro Ser Gly Glu Lys Ile Thr Phe Leu Asp Thr Pro Gly His Ala Ala 
225                 230                 235                 240 


Phe Ser Ala Met Arg Ala Arg Gly Ala Gln Val Thr Asp Ile Val Val 
                245                 250                 255     


Leu Val Val Ala Ala Asp Asp Gly Val Met Lys Gln Thr Val Glu Ser 
            260                 265                 270         


Ile Gln His Ala Lys Asp Ala Gln Val Pro Ile Ile Leu Ala Val Asn 
        275                 280                 285             


Lys Cys Asp Lys Ala Glu Ala Asp Pro Glu Lys Val Lys Lys Glu Leu 
    290                 295                 300                 


Leu Ala Tyr Asp Val Val Cys Glu Asp Tyr Gly Gly Asp Val Gln Ala 
305                 310                 315                 320 


Val Pro Val Ser Ala Leu Thr Gly Asp Asn Leu Met Ala Leu Ala Glu 
                325                 330                 335     


Ala Thr Val Ala Leu Ala Glu Met Leu Glu Leu Lys Ala Asp Pro Asn 
            340                 345                 350         


Gly Pro Val Glu Gly Thr Val Ile Glu Ser Phe Thr Asp Lys Gly Arg 
        355                 360                 365             


Gly Leu Val Thr Thr Ala Ile Ile Gln Arg Gly Thr Leu Arg Lys Gly 
    370                 375                 380                 


Ser Val Leu Val Ala Gly Lys Cys Trp Ala Lys Val Arg Leu Met Phe 
385                 390                 395                 400 


Asp Glu Asn Gly Lys Thr Ile Asp Glu Ala Tyr Pro Ser Met Pro Val 
                405                 410                 415     


Gly Ile Thr Gly Trp Arg Asp Leu Pro Ser Ala Gly Glu Glu Ile Leu 
            420                 425                 430         


Glu Val Glu Ser Glu Pro Arg Ala Arg Glu Val Val Asp Trp Arg Lys 
        435                 440                 445             


Tyr Glu Gln Glu Gln Glu Lys Gly Gln Glu Asp Leu Lys Ile Ile Glu 
    450                 455                 460                 


Glu Lys Arg Lys Glu His Lys Glu Ala His Gln Lys Ala Arg Glu Lys 
465                 470                 475                 480 


Tyr Gly His Leu Leu Trp Lys Lys Arg Ser Ile Leu Arg Phe Leu Glu 
                485                 490                 495     


Arg Lys Glu Gln Ile Pro Leu Lys Pro Lys Glu Lys Arg Glu Arg Asp 
            500                 505                 510         


Ser Asn Val Leu Ser Val Ile Ile Lys Gly Asp Val Asp Gly Ser Val 
        515                 520                 525             


Glu Ala Ile Leu Asn Ile Ile Asp Thr Tyr Asp Ala Ser His Glu Cys 
    530                 535                 540                 


Glu Leu Glu Leu Val His Phe Gly Val Gly Asp Val Ser Ala Asn Asp 
545                 550                 555                 560 


Val Asn Leu Ala Glu Thr Phe Asp Gly Val Ile Tyr Gly Phe Asn Val 
                565                 570                 575     


Asn Ala Gly Asn Val Ile Gln Gln Ser Ala Ala Lys Lys Gly Val Lys 
            580                 585                 590         


Ile Lys Leu His Lys Ile Ile Tyr Arg Leu Val Glu Asp Leu Gln Glu 
        595                 600                 605             


Glu Leu Ser Ser Arg Leu Pro Cys Ala Val Glu Glu His Pro Val Gly 
    610                 615                 620                 


Glu Ala Ser Ile Leu Ala Thr Phe Ser Val Thr Glu Gly Lys Lys Lys 
625                 630                 635                 640 


Val Pro Val Ala Gly Cys Arg Val Gln Lys Gly Gln Leu Glu Lys Gln 
                645                 650                 655     


Lys Lys Phe Lys Leu Thr Arg Asn Gly His Val Ile Trp Lys Gly Ser 
            660                 665                 670         


Leu Thr Ser Leu Lys His His Lys Asp Asp Ile Ser Ile Val Lys Thr 
        675                 680                 685             


Gly Met Asp Cys Gly Leu Ser Leu Asp Glu Asp Asn Met Glu Phe Gln 
    690                 695                 700                 


Val Gly Asp Arg Ile Val Cys Tyr Glu Glu Lys Gln Ile Gln Ala Lys 
705                 710                 715                 720 


Thr Ser Trp Asp Pro Gly Phe 
                725         


<210>  3677
<211>  271
<212>  PRT
<213>  homo sapiens

<400>  3677

Met Gln Ala Ala Cys Trp Tyr Val Leu Phe Leu Leu Gln Pro Thr Val 
1               5                   10                  15      


Tyr Leu Val Thr Cys Ala Asn Leu Thr Asn Gly Gly Lys Ser Glu Leu 
            20                  25                  30          


Leu Lys Ser Gly Ser Ser Lys Ser Thr Leu Lys His Ile Trp Thr Glu 
        35                  40                  45              


Ser Ser Lys Asp Leu Ser Ile Ser Arg Leu Leu Ser Gln Thr Phe Arg 
    50                  55                  60                  


Gly Lys Glu Asn Asp Thr Asp Leu Asp Leu Arg Tyr Asp Thr Pro Glu 
65                  70                  75                  80  


Pro Tyr Ser Glu Gln Asp Leu Trp Asp Trp Leu Arg Asn Ser Thr Asp 
                85                  90                  95      


Leu Gln Glu Pro Arg Pro Arg Ala Lys Arg Arg Pro Ile Val Lys Thr 
            100                 105                 110         


Gly Lys Phe Lys Lys Met Phe Gly Trp Gly Asp Phe His Ser Asn Ile 
        115                 120                 125             


Lys Thr Val Lys Leu Asn Leu Leu Ile Thr Gly Lys Ile Val Asp His 
    130                 135                 140                 


Gly Asn Gly Thr Phe Ser Val Tyr Phe Arg His Asn Ser Thr Gly Gln 
145                 150                 155                 160 


Gly Asn Val Ser Val Ser Leu Val Pro Pro Thr Lys Ile Val Glu Phe 
                165                 170                 175     


Asp Leu Ala Gln Gln Thr Val Ile Asp Ala Lys Asp Ser Lys Ser Phe 
            180                 185                 190         


Asn Cys Arg Ile Glu Tyr Glu Lys Val Asp Lys Ala Thr Lys Asn Thr 
        195                 200                 205             


Leu Cys Asn Tyr Asp Pro Ser Lys Thr Cys Tyr Gln Glu Gln Thr Gln 
    210                 215                 220                 


Ser His Val Ser Trp Leu Cys Ser Lys Pro Phe Lys Val Ile Cys Ile 
225                 230                 235                 240 


Tyr Ile Ser Phe Tyr Ser Thr Asp Tyr Lys Leu Val Gln Lys Val Cys 
                245                 250                 255     


Pro Asp Tyr Asn Tyr His Ser Asp Thr Pro Tyr Phe Pro Ser Gly 
            260                 265                 270     


<210>  3678
<211>  99
<212>  PRT
<213>  homo sapiens

<400>  3678

Met Ala Ser Ala Ser Ala Arg Gly Asn Gln Asp Lys Asp Ala His Phe 
1               5                   10                  15      


Pro Pro Pro Ser Lys Gln Ser Leu Leu Phe Cys Pro Lys Ser Lys Leu 
            20                  25                  30          


His Ile His Arg Ala Glu Ile Ser Lys Ile Met Arg Glu Cys Gln Glu 
        35                  40                  45              


Glu Ser Phe Trp Lys Arg Ala Leu Pro Phe Ser Leu Val Ser Met Leu 
    50                  55                  60                  


Val Thr Gln Gly Leu Val Tyr Gln Gly Tyr Leu Ala Ala Asn Ser Arg 
65                  70                  75                  80  


Phe Gly Ser Leu Pro Lys Val Ala Arg Thr Ala Ser Leu Pro Val Arg 
                85                  90                  95      


Asn Ala Lys 
            


<210>  3679
<211>  484
<212>  PRT
<213>  homo sapiens

<400>  3679

Met Thr Thr Leu Ala Gly Ala Val Pro Arg Met Met Arg Pro Gly Pro 
1               5                   10                  15      


Gly Gln Asn Tyr Pro Arg Ser Gly Phe Pro Leu Glu Val Ser Thr Pro 
            20                  25                  30          


Leu Gly Gln Gly Arg Val Asn Gln Leu Gly Gly Val Phe Ile Asn Gly 
        35                  40                  45              


Arg Pro Leu Pro Asn His Ile Arg His Lys Ile Val Glu Met Ala His 
    50                  55                  60                  


His Gly Ile Arg Pro Cys Val Ile Ser Arg Gln Leu Arg Val Ser His 
65                  70                  75                  80  


Gly Cys Val Ser Lys Ile Leu Cys Arg Tyr Gln Glu Thr Gly Ser Ile 
                85                  90                  95      


Arg Pro Gly Ala Ile Gly Gly Ser Lys Pro Lys Gln Val Thr Thr Pro 
            100                 105                 110         


Asp Val Glu Lys Lys Ile Glu Glu Tyr Lys Arg Glu Asn Pro Gly Met 
        115                 120                 125             


Phe Ser Trp Glu Ile Arg Asp Lys Leu Leu Lys Asp Ala Val Cys Asp 
    130                 135                 140                 


Arg Asn Thr Val Pro Ser Val Ser Ser Ile Ser Arg Ile Leu Arg Ser 
145                 150                 155                 160 


Lys Phe Gly Lys Gly Glu Glu Glu Glu Ala Asp Leu Glu Arg Lys Glu 
                165                 170                 175     


Ala Glu Glu Ser Glu Lys Lys Ala Lys His Ser Ile Asp Gly Ile Leu 
            180                 185                 190         


Ser Glu Arg Ala Ser Ala Pro Gln Ser Asp Glu Gly Ser Asp Ile Asp 
        195                 200                 205             


Ser Glu Pro Asp Leu Pro Leu Lys Arg Lys Gln Arg Arg Ser Arg Thr 
    210                 215                 220                 


Thr Phe Thr Ala Glu Gln Leu Glu Glu Leu Glu Arg Ala Phe Glu Arg 
225                 230                 235                 240 


Thr His Tyr Pro Asp Ile Tyr Thr Arg Glu Glu Leu Ala Gln Arg Ala 
                245                 250                 255     


Lys Leu Thr Glu Ala Arg Val Gln Val Trp Phe Ser Asn Arg Arg Ala 
            260                 265                 270         


Arg Trp Arg Lys Gln Ala Gly Ala Asn Gln Leu Met Ala Phe Asn His 
        275                 280                 285             


Leu Ile Pro Gly Gly Phe Pro Pro Thr Ala Met Pro Thr Leu Pro Thr 
    290                 295                 300                 


Tyr Gln Leu Ser Glu Thr Ser Tyr Gln Pro Thr Ser Ile Pro Gln Ala 
305                 310                 315                 320 


Val Ser Asp Pro Ser Ser Thr Val His Arg Pro Gln Pro Leu Pro Pro 
                325                 330                 335     


Ser Thr Val His Gln Ser Thr Ile Pro Ser Asn Pro Asp Ser Ser Ser 
            340                 345                 350         


Ala Tyr Cys Leu Pro Ser Thr Arg His Gly Phe Ser Ser Tyr Thr Asp 
        355                 360                 365             


Ser Phe Val Pro Pro Ser Gly Pro Ser Asn Pro Met Asn Pro Thr Ile 
    370                 375                 380                 


Gly Asn Gly Leu Ser Pro Gln Val Met Gly Leu Leu Thr Asn His Gly 
385                 390                 395                 400 


Gly Val Pro His Gln Pro Gln Thr Asp Tyr Ala Leu Ser Pro Leu Thr 
                405                 410                 415     


Gly Gly Leu Glu Pro Thr Thr Thr Val Ser Ala Ser Cys Ser Gln Arg 
            420                 425                 430         


Leu Asp His Met Lys Ser Leu Asp Ser Leu Pro Thr Ser Gln Ser Tyr 
        435                 440                 445             


Cys Pro Pro Thr Tyr Ser Thr Thr Gly Tyr Ser Met Asp Pro Val Thr 
    450                 455                 460                 


Gly Tyr Gln Tyr Gly Gln Tyr Gly Gln Ser Ala Phe His Tyr Leu Lys 
465                 470                 475                 480 


Pro Asp Ile Ala 
                


<210>  3680
<211>  505
<212>  PRT
<213>  homo sapiens

<400>  3680

Met Thr Thr Leu Ala Gly Ala Val Pro Arg Met Met Arg Pro Gly Pro 
1               5                   10                  15      


Gly Gln Asn Tyr Pro Arg Ser Gly Phe Pro Leu Glu Val Ser Thr Pro 
            20                  25                  30          


Leu Gly Gln Gly Arg Val Asn Gln Leu Gly Gly Val Phe Ile Asn Gly 
        35                  40                  45              


Arg Pro Leu Pro Asn His Ile Arg His Lys Ile Val Glu Met Ala His 
    50                  55                  60                  


His Gly Ile Arg Pro Cys Val Ile Ser Arg Gln Leu Arg Val Ser His 
65                  70                  75                  80  


Gly Cys Val Ser Lys Ile Leu Cys Arg Tyr Gln Glu Thr Gly Ser Ile 
                85                  90                  95      


Arg Pro Gly Ala Ile Gly Gly Ser Lys Pro Lys Gln Val Thr Thr Pro 
            100                 105                 110         


Asp Val Glu Lys Lys Ile Glu Glu Tyr Lys Arg Glu Asn Pro Gly Met 
        115                 120                 125             


Phe Ser Trp Glu Ile Arg Asp Lys Leu Leu Lys Asp Ala Val Cys Asp 
    130                 135                 140                 


Arg Asn Thr Val Pro Ser Val Ser Ser Ile Ser Arg Ile Leu Arg Ser 
145                 150                 155                 160 


Lys Phe Gly Lys Gly Glu Glu Glu Glu Ala Asp Leu Glu Arg Lys Glu 
                165                 170                 175     


Ala Glu Glu Ser Glu Lys Lys Ala Lys His Ser Ile Asp Gly Ile Leu 
            180                 185                 190         


Ser Glu Arg Ala Ser Ala Pro Gln Ser Asp Glu Gly Ser Asp Ile Asp 
        195                 200                 205             


Ser Glu Pro Asp Leu Pro Leu Lys Arg Lys Gln Arg Arg Ser Arg Thr 
    210                 215                 220                 


Thr Phe Thr Ala Glu Gln Leu Glu Glu Leu Glu Arg Ala Phe Glu Arg 
225                 230                 235                 240 


Thr His Tyr Pro Asp Ile Tyr Thr Arg Glu Glu Leu Ala Gln Arg Ala 
                245                 250                 255     


Lys Leu Thr Glu Ala Arg Val Gln Val Trp Phe Ser Asn Arg Arg Ala 
            260                 265                 270         


Arg Trp Arg Lys Gln Ala Gly Ala Asn Gln Leu Met Ala Phe Asn His 
        275                 280                 285             


Leu Ile Pro Gly Gly Phe Pro Pro Thr Ala Met Pro Thr Leu Pro Thr 
    290                 295                 300                 


Tyr Gln Leu Ser Glu Thr Ser Tyr Gln Pro Thr Ser Ile Pro Gln Ala 
305                 310                 315                 320 


Val Ser Asp Pro Ser Ser Thr Val His Arg Pro Gln Pro Leu Pro Pro 
                325                 330                 335     


Ser Thr Val His Gln Ser Thr Ile Pro Ser Asn Pro Asp Ser Ser Ser 
            340                 345                 350         


Ala Tyr Cys Leu Pro Ser Thr Arg His Gly Phe Ser Ser Tyr Thr Asp 
        355                 360                 365             


Ser Phe Val Pro Pro Ser Gly Pro Ser Asn Pro Met Asn Pro Thr Ile 
    370                 375                 380                 


Gly Asn Gly Leu Ser Pro Gln Val Met Gly Leu Leu Thr Asn His Gly 
385                 390                 395                 400 


Gly Val Pro His Gln Pro Gln Thr Asp Tyr Ala Leu Ser Pro Leu Thr 
                405                 410                 415     


Gly Gly Leu Glu Pro Thr Thr Thr Val Ser Ala Ser Cys Ser Gln Arg 
            420                 425                 430         


Leu Asp His Met Lys Ser Leu Asp Ser Leu Pro Thr Ser Gln Ser Tyr 
        435                 440                 445             


Cys Pro Pro Thr Tyr Ser Thr Thr Gly Tyr Ser Met Asp Pro Val Thr 
    450                 455                 460                 


Gly Tyr Gln Tyr Gly Gln Tyr Gly Gln Ser Ala Phe His Tyr Leu Lys 
465                 470                 475                 480 


Pro Asp Ile Ala Trp Phe Gln Ile Leu Leu Asn Thr Phe Asp Lys Ser 
                485                 490                 495     


Ser Gly Glu Glu Glu Asp Leu Glu Gln 
            500                 505 


<210>  3681
<211>  622
<212>  PRT
<213>  homo sapiens

<400>  3681

Met Gly Leu Tyr Gly Gln Ala Cys Pro Ser Val Thr Ser Leu Arg Met 
1               5                   10                  15      


Thr Ser Glu Leu Glu Ser Ser Leu Thr Ser Met Asp Trp Leu Pro Gln 
            20                  25                  30          


Leu Thr Met Arg Ala Ala Ile Gln Lys Ser Asp Ala Thr Gln Asn Ala 
        35                  40                  45              


His Gly Thr Gly Ile Ser Lys Lys Asn Ala Leu Leu Asp Pro Asn Thr 
    50                  55                  60                  


Thr Leu Asp Gln Glu Glu Val Gln Gln His Lys Asp Gly Lys Pro Pro 
65                  70                  75                  80  


Tyr Ser Tyr Ala Ser Leu Ile Thr Phe Ala Ile Asn Ser Ser Pro Lys 
                85                  90                  95      


Lys Lys Met Thr Leu Ser Glu Ile Tyr Gln Trp Ile Cys Asp Asn Phe 
            100                 105                 110         


Pro Tyr Tyr Arg Glu Ala Gly Ser Gly Trp Lys Asn Ser Ile Arg His 
        115                 120                 125             


Asn Leu Ser Leu Asn Lys Cys Phe Leu Lys Val Pro Arg Ser Lys Asp 
    130                 135                 140                 


Asp Pro Gly Lys Gly Ser Tyr Trp Ala Ile Asp Thr Asn Pro Lys Glu 
145                 150                 155                 160 


Asp Val Leu Pro Thr Arg Pro Lys Lys Arg Ala Arg Ser Val Glu Arg 
                165                 170                 175     


Ala Ser Thr Pro Tyr Ser Ile Asp Ser Asp Ser Leu Gly Met Glu Cys 
            180                 185                 190         


Ile Ile Ser Gly Ser Ala Ser Pro Thr Leu Ala Ile Asn Thr Val Thr 
        195                 200                 205             


Asn Lys Val Thr Leu Tyr Asn Thr Asp Gln Asp Gly Ser Asp Ser Pro 
    210                 215                 220                 


Arg Ser Ser Leu Asn Asn Ser Leu Ser Asp Gln Ser Leu Ala Ser Val 
225                 230                 235                 240 


Asn Leu Asn Ser Val Gly Ser Val His Ser Tyr Thr Pro Val Thr Ser 
                245                 250                 255     


His Pro Glu Ser Val Ser Gln Ser Leu Thr Pro Gln Gln Gln Pro Gln 
            260                 265                 270         


Tyr Asn Leu Pro Glu Arg Asp Lys Gln Leu Leu Phe Ser Glu Tyr Asn 
        275                 280                 285             


Phe Glu Asp Leu Ser Ala Ser Phe Arg Ser Leu Tyr Lys Ser Val Phe 
    290                 295                 300                 


Glu Gln Ser Leu Ser Gln Gln Gly Leu Met Asn Ile Pro Ser Glu Ser 
305                 310                 315                 320 


Ser Gln Gln Ser His Thr Ser Cys Thr Tyr Gln His Ser Pro Ser Ser 
                325                 330                 335     


Thr Val Ser Thr His Pro His Ser Asn Gln Ser Ser Leu Ser Asn Ser 
            340                 345                 350         


His Gly Ser Gly Leu Asn Thr Thr Gly Ser Asn Ser Val Ala Gln Val 
        355                 360                 365             


Ser Leu Ser His Pro Gln Met His Thr Gln Pro Ser Pro His Pro Pro 
    370                 375                 380                 


His Arg Pro His Gly Leu Pro Gln His Pro Gln Arg Ser Pro His Pro 
385                 390                 395                 400 


Ala Pro His Pro Gln Gln His Ser Gln Leu Gln Ser Pro His Pro Gln 
                405                 410                 415     


His Pro Ser Pro His Gln His Ile Gln His His Pro Asn His Gln His 
            420                 425                 430         


Gln Thr Leu Thr His Gln Ala Pro Pro Pro Pro Gln Gln Val Ser Cys 
        435                 440                 445             


Asn Ser Gly Val Ser Asn Asp Trp Tyr Ala Thr Leu Asp Met Leu Lys 
    450                 455                 460                 


Glu Ser Cys Arg Ile Ala Ser Ser Val Asn Trp Ser Asp Val Asp Leu 
465                 470                 475                 480 


Ser Gln Phe Gln Gly Leu Met Glu Ser Met Arg Gln Ala Asp Leu Lys 
                485                 490                 495     


Asn Trp Ser Leu Asp Gln Val Gln Phe Ala Asp Leu Cys Ser Ser Leu 
            500                 505                 510         


Asn Gln Phe Phe Thr Gln Thr Gly Leu Ile His Ser Gln Ser Asn Val 
        515                 520                 525             


Gln Gln Asn Val Cys His Gly Ala Met His Pro Thr Lys Pro Ser Gln 
    530                 535                 540                 


His Ile Gly Thr Gly Asn Leu Tyr Ile Asp Ser Arg Gln Asn Leu Pro 
545                 550                 555                 560 


Pro Ser Val Met Pro Pro Pro Gly Tyr Pro His Ile Pro Gln Ala Leu 
                565                 570                 575     


Ser Thr Pro Gly Thr Thr Met Ala Gly His His Arg Ala Met Asn Gln 
            580                 585                 590         


Gln His Met Met Pro Ser Gln Ala Phe Gln Met Arg Arg Ser Leu Pro 
        595                 600                 605             


Pro Asp Asp Ile Gln Asp Asp Phe Asp Trp Asp Ser Ile Val 
    610                 615                 620         


<210>  3682
<211>  708
<212>  PRT
<213>  homo sapiens

<400>  3682

Met Lys Asp Met Pro Leu Arg Ile His Val Leu Leu Gly Leu Ala Ile 
1               5                   10                  15      


Thr Thr Leu Val Gln Ala Val Asp Lys Lys Val Asp Cys Pro Arg Leu 
            20                  25                  30          


Cys Thr Cys Glu Ile Arg Pro Trp Phe Thr Pro Arg Ser Ile Tyr Met 
        35                  40                  45              


Glu Ala Ser Thr Val Asp Cys Asn Asp Leu Gly Leu Leu Thr Phe Pro 
    50                  55                  60                  


Ala Arg Leu Pro Ala Asn Thr Gln Ile Leu Leu Leu Gln Thr Asn Asn 
65                  70                  75                  80  


Ile Ala Lys Ile Glu Tyr Ser Thr Asp Phe Pro Val Asn Leu Thr Gly 
                85                  90                  95      


Leu Asp Leu Ser Gln Asn Asn Leu Ser Ser Val Thr Asn Ile Asn Val 
            100                 105                 110         


Lys Lys Met Pro Gln Leu Leu Ser Val Tyr Leu Glu Glu Asn Lys Leu 
        115                 120                 125             


Thr Glu Leu Pro Glu Lys Cys Leu Ser Glu Leu Ser Asn Leu Gln Glu 
    130                 135                 140                 


Leu Tyr Ile Asn His Asn Leu Leu Ser Thr Ile Ser Pro Gly Ala Phe 
145                 150                 155                 160 


Ile Gly Leu His Asn Leu Leu Arg Leu His Leu Asn Ser Asn Arg Leu 
                165                 170                 175     


Gln Met Ile Asn Ser Lys Trp Phe Asp Ala Leu Pro Asn Leu Glu Ile 
            180                 185                 190         


Leu Met Ile Gly Glu Asn Pro Ile Ile Arg Ile Lys Asp Met Asn Phe 
        195                 200                 205             


Lys Pro Leu Ile Asn Leu Arg Ser Leu Val Ile Ala Gly Ile Asn Leu 
    210                 215                 220                 


Thr Glu Ile Pro Asp Asn Ala Leu Val Gly Leu Glu Asn Leu Glu Ser 
225                 230                 235                 240 


Ile Ser Phe Tyr Asp Asn Arg Leu Ile Lys Val Pro His Val Ala Leu 
                245                 250                 255     


Gln Lys Val Val Asn Leu Lys Phe Leu Asp Leu Asn Lys Asn Pro Ile 
            260                 265                 270         


Asn Arg Ile Arg Arg Gly Asp Phe Ser Asn Met Leu His Leu Lys Glu 
        275                 280                 285             


Leu Gly Ile Asn Asn Met Pro Glu Leu Ile Ser Ile Asp Ser Leu Ala 
    290                 295                 300                 


Val Asp Asn Leu Pro Asp Leu Arg Lys Ile Glu Ala Thr Asn Asn Pro 
305                 310                 315                 320 


Arg Leu Ser Tyr Ile His Pro Asn Ala Phe Phe Arg Leu Pro Lys Leu 
                325                 330                 335     


Glu Ser Leu Met Leu Asn Ser Asn Ala Leu Ser Ala Leu Tyr His Gly 
            340                 345                 350         


Thr Ile Glu Ser Leu Pro Asn Leu Lys Glu Ile Ser Ile His Ser Asn 
        355                 360                 365             


Pro Ile Arg Cys Asp Cys Val Ile Arg Trp Met Asn Met Asn Lys Thr 
    370                 375                 380                 


Asn Ile Arg Phe Met Glu Pro Asp Ser Leu Phe Cys Val Asp Pro Pro 
385                 390                 395                 400 


Glu Phe Gln Gly Gln Asn Val Arg Gln Val His Phe Arg Asp Met Met 
                405                 410                 415     


Glu Ile Cys Leu Pro Leu Ile Ala Pro Glu Ser Phe Pro Ser Asn Leu 
            420                 425                 430         


Asn Val Glu Ala Gly Ser Tyr Val Ser Phe His Cys Arg Ala Thr Ala 
        435                 440                 445             


Glu Pro Gln Pro Glu Ile Tyr Trp Ile Thr Pro Ser Gly Gln Lys Leu 
    450                 455                 460                 


Leu Pro Asn Thr Leu Thr Asp Lys Phe Tyr Val His Ser Glu Gly Thr 
465                 470                 475                 480 


Leu Asp Ile Asn Gly Val Thr Pro Lys Glu Gly Gly Leu Tyr Thr Cys 
                485                 490                 495     


Ile Ala Thr Asn Leu Val Gly Ala Asp Leu Lys Ser Val Met Ile Lys 
            500                 505                 510         


Val Asp Gly Ser Phe Pro Gln Asp Asn Asn Gly Ser Leu Asn Ile Lys 
        515                 520                 525             


Ile Arg Asp Ile Gln Ala Asn Ser Val Leu Val Ser Trp Lys Ala Ser 
    530                 535                 540                 


Ser Lys Ile Leu Lys Ser Ser Val Lys Trp Thr Ala Phe Val Lys Thr 
545                 550                 555                 560 


Glu Asn Ser His Ala Ala Gln Ser Ala Arg Ile Pro Ser Asp Val Lys 
                565                 570                 575     


Val Tyr Asn Leu Thr His Leu Asn Pro Ser Thr Glu Tyr Lys Ile Cys 
            580                 585                 590         


Ile Asp Ile Pro Thr Ile Tyr Gln Lys Asn Arg Lys Lys Cys Val Asn 
        595                 600                 605             


Val Thr Thr Lys Gly Leu His Pro Asp Gln Lys Glu Tyr Glu Lys Asn 
    610                 615                 620                 


Asn Thr Thr Thr Leu Met Ala Cys Leu Gly Gly Leu Leu Gly Ile Ile 
625                 630                 635                 640 


Gly Val Ile Cys Leu Ile Ser Cys Leu Ser Pro Glu Met Asn Cys Asp 
                645                 650                 655     


Gly Gly His Ser Tyr Val Arg Asn Tyr Leu Gln Lys Pro Thr Phe Ala 
            660                 665                 670         


Leu Gly Glu Leu Tyr Pro Pro Leu Ile Asn Leu Trp Glu Ala Gly Lys 
        675                 680                 685             


Glu Lys Ser Thr Ser Leu Lys Val Lys Ala Thr Val Ile Gly Leu Pro 
    690                 695                 700                 


Thr Asn Met Ser 
705             


<210>  3683
<211>  776
<212>  PRT
<213>  homo sapiens

<400>  3683

Met Ala Ala Pro Gly Asp Pro Gln Asp Glu Leu Leu Pro Leu Ala Gly 
1               5                   10                  15      


Pro Gly Ser Gln Trp Leu Arg His Arg Gly Glu Gly Glu Asn Glu Ala 
            20                  25                  30          


Val Thr Pro Lys Gly Ala Thr Pro Ala Pro Gln Ala Gly Glu Pro Ser 
        35                  40                  45              


Pro Gly Leu Gly Ala Arg Ala Arg Glu Ala Ala Ser Arg Glu Ala Gly 
    50                  55                  60                  


Ser Gly Pro Ala Arg Gln Ser Pro Val Ala Met Glu Thr Ala Ser Thr 
65                  70                  75                  80  


Gly Val Ala Gly Val Ser Ser Ala Met Asp His Thr Phe Ser Thr Thr 
                85                  90                  95      


Ser Lys Asp Gly Glu Gly Ser Cys Tyr Thr Ser Leu Ile Ser Asp Ile 
            100                 105                 110         


Cys Tyr Pro Pro Gln Glu Asp Ser Thr Tyr Phe Thr Gly Ile Leu Gln 
        115                 120                 125             


Lys Glu Asn Gly His Val Thr Ile Ser Glu Ser Pro Glu Glu Leu Gly 
    130                 135                 140                 


Thr Pro Gly Pro Ser Leu Pro Asp Val Pro Gly Ile Glu Ser Arg Gly 
145                 150                 155                 160 


Leu Phe Ser Ser Asp Ser Gly Ile Glu Met Thr Pro Ala Glu Ser Thr 
                165                 170                 175     


Glu Val Asn Lys Ile Leu Ala Asp Pro Leu Asp Gln Met Lys Ala Glu 
            180                 185                 190         


Ala Tyr Lys Tyr Ile Asp Ile Thr Arg Pro Glu Glu Val Lys His Gln 
        195                 200                 205             


Glu Gln His His Pro Glu Leu Glu Asp Lys Asp Leu Asp Phe Lys Asn 
    210                 215                 220                 


Lys Asp Thr Asp Ile Ser Ile Lys Pro Glu Gly Val Arg Glu Pro Asp 
225                 230                 235                 240 


Lys Pro Ala Pro Val Glu Gly Lys Ile Ile Lys Asp His Leu Leu Glu 
                245                 250                 255     


Glu Ser Thr Phe Ala Pro Tyr Ile Asp Asp Leu Ser Glu Glu Gln Arg 
            260                 265                 270         


Arg Ala Pro Gln Ile Thr Thr Pro Val Lys Ile Thr Leu Thr Glu Ile 
        275                 280                 285             


Glu Pro Ser Val Glu Thr Thr Thr Gln Glu Lys Thr Pro Glu Lys Gln 
    290                 295                 300                 


Asp Ile Cys Leu Lys Pro Ser Pro Asp Thr Val Pro Thr Val Thr Val 
305                 310                 315                 320 


Ser Glu Pro Glu Asp Asp Ser Pro Gly Ser Ile Thr Pro Pro Ser Ser 
                325                 330                 335     


Gly Thr Glu Pro Ser Ala Ala Glu Ser Gln Gly Lys Gly Ser Ile Ser 
            340                 345                 350         


Glu Asp Glu Leu Ile Thr Ala Ile Lys Glu Ala Lys Gly Leu Ser Tyr 
        355                 360                 365             


Glu Thr Ala Glu Asn Pro Arg Pro Val Gly Gln Leu Ala Asp Arg Pro 
    370                 375                 380                 


Glu Val Lys Ala Arg Ser Gly Pro Pro Thr Ile Pro Ser Pro Leu Asp 
385                 390                 395                 400 


His Glu Ala Ser Ser Ala Glu Ser Gly Asp Ser Glu Ile Glu Leu Val 
                405                 410                 415     


Ser Glu Asp Pro Met Ala Ala Glu Asp Ala Leu Pro Ser Gly Tyr Val 
            420                 425                 430         


Ser Phe Gly His Val Gly Gly Pro Pro Pro Ser Pro Ala Ser Pro Ser 
        435                 440                 445             


Ile Gln Tyr Ser Ile Leu Arg Glu Glu Arg Glu Ala Glu Leu Asp Ser 
    450                 455                 460                 


Glu Leu Ile Ile Glu Ser Cys Asp Ala Ser Ser Ala Ser Glu Glu Ser 
465                 470                 475                 480 


Pro Lys Arg Glu Gln Asp Ser Pro Pro Met Lys Pro Ser Ala Leu Asp 
                485                 490                 495     


Ala Ile Arg Glu Glu Thr Gly Val Arg Ala Glu Glu Arg Ala Pro Ser 
            500                 505                 510         


Arg Arg Gly Leu Ala Glu Pro Gly Ser Phe Leu Asp Tyr Pro Ser Thr 
        515                 520                 525             


Glu Pro Gln Pro Gly Pro Glu Leu Pro Pro Gly Asp Gly Ala Leu Glu 
    530                 535                 540                 


Pro Glu Thr Pro Met Leu Pro Arg Lys Pro Glu Glu Asp Ser Ser Ser 
545                 550                 555                 560 


Asn Gln Ser Pro Ala Ala Thr Lys Gly Pro Gly Pro Leu Gly Pro Gly 
                565                 570                 575     


Ala Pro Pro Pro Leu Leu Phe Leu Asn Lys Gln Lys Ala Ile Asp Leu 
            580                 585                 590         


Leu Tyr Trp Arg Asp Ile Lys Gln Thr Gly Ile Val Phe Gly Ser Phe 
        595                 600                 605             


Leu Leu Leu Leu Phe Ser Leu Thr Gln Phe Ser Val Val Ser Val Val 
    610                 615                 620                 


Ala Tyr Leu Ala Leu Ala Ala Leu Ser Ala Thr Ile Ser Phe Arg Ile 
625                 630                 635                 640 


Tyr Lys Ser Val Leu Gln Ala Val Gln Lys Thr Asp Glu Gly His Pro 
                645                 650                 655     


Phe Lys Ala Tyr Leu Glu Leu Glu Ile Thr Leu Ser Gln Glu Gln Ile 
            660                 665                 670         


Gln Lys Tyr Thr Asp Cys Leu Gln Phe Tyr Val Asn Ser Thr Leu Lys 
        675                 680                 685             


Glu Leu Arg Arg Leu Phe Leu Val Gln Asp Leu Val Asp Ser Leu Lys 
    690                 695                 700                 


Phe Ala Val Leu Met Trp Leu Leu Thr Tyr Val Gly Ala Leu Phe Asn 
705                 710                 715                 720 


Gly Leu Thr Leu Leu Leu Met Ala Val Val Ser Met Phe Thr Leu Pro 
                725                 730                 735     


Val Val Tyr Val Lys His Gln Ala Gln Ile Asp Gln Tyr Leu Gly Leu 
            740                 745                 750         


Val Arg Thr His Ile Asn Ala Val Val Ala Lys Ile Gln Ala Lys Ile 
        755                 760                 765             


Pro Gly Ala Lys Arg His Ala Glu 
    770                 775     


<210>  3684
<211>  1865
<212>  PRT
<213>  homo sapiens

<400>  3684

Met Thr Arg Trp Val Pro Thr Lys Arg Glu Glu Lys Tyr Gly Val Ala 
1               5                   10                  15      


Phe Tyr Asn Tyr Asp Ala Arg Gly Ala Asp Glu Leu Ser Leu Gln Ile 
            20                  25                  30          


Gly Asp Thr Val His Ile Leu Glu Thr Tyr Glu Gly Trp Tyr Arg Gly 
        35                  40                  45              


Tyr Thr Leu Arg Lys Lys Ser Lys Lys Gly Ile Phe Pro Ala Ser Tyr 
    50                  55                  60                  


Ile His Leu Lys Glu Ala Ile Val Glu Gly Lys Gly Gln His Glu Thr 
65                  70                  75                  80  


Val Ile Pro Gly Asp Leu Pro Leu Ile Gln Glu Val Thr Thr Thr Leu 
                85                  90                  95      


Arg Glu Trp Ser Thr Ile Trp Arg Gln Leu Tyr Val Gln Asp Asn Arg 
            100                 105                 110         


Glu Met Phe Arg Ser Val Arg His Met Ile Tyr Asp Leu Ile Glu Trp 
        115                 120                 125             


Arg Ser Gln Ile Leu Ser Gly Thr Leu Pro Gln Asp Glu Leu Lys Glu 
    130                 135                 140                 


Leu Lys Lys Lys Val Thr Ala Lys Ile Asp Tyr Gly Asn Arg Ile Leu 
145                 150                 155                 160 


Asp Leu Asp Leu Val Val Arg Asp Glu Asp Gly Asn Ile Leu Asp Pro 
                165                 170                 175     


Glu Leu Thr Ser Thr Ile Ser Leu Phe Arg Ala His Glu Ile Ala Ser 
            180                 185                 190         


Lys Gln Val Glu Glu Arg Leu Gln Glu Glu Lys Ser Gln Lys Gln Asn 
        195                 200                 205             


Ile Asp Ile Asn Arg Gln Ala Lys Phe Ala Ala Thr Pro Ser Leu Ala 
    210                 215                 220                 


Leu Phe Val Asn Leu Lys Asn Val Val Cys Lys Ile Gly Glu Asp Ala 
225                 230                 235                 240 


Glu Val Leu Met Ser Leu Tyr Asp Pro Val Glu Ser Lys Phe Ile Ser 
                245                 250                 255     


Glu Asn Tyr Leu Val Arg Trp Ser Ser Ser Gly Leu Pro Lys Asp Ile 
            260                 265                 270         


Asp Arg Leu His Asn Leu Arg Ala Val Phe Thr Asp Leu Gly Ser Lys 
        275                 280                 285             


Asp Leu Lys Arg Glu Lys Ile Ser Phe Val Cys Gln Ile Val Arg Val 
    290                 295                 300                 


Gly Arg Met Glu Leu Arg Asp Asn Asn Thr Arg Lys Leu Thr Ser Gly 
305                 310                 315                 320 


Leu Arg Arg Pro Phe Gly Val Ala Val Met Asp Val Thr Asp Ile Ile 
                325                 330                 335     


Asn Gly Lys Val Asp Asp Glu Asp Lys Gln His Phe Ile Pro Phe Gln 
            340                 345                 350         


Pro Val Ala Gly Glu Asn Asp Phe Leu Gln Thr Val Ile Asn Lys Val 
        355                 360                 365             


Ile Ala Ala Lys Glu Val Asn His Lys Gly Gln Gly Leu Trp Val Thr 
    370                 375                 380                 


Leu Lys Leu Leu Pro Gly Asp Ile His Gln Ile Arg Lys Glu Phe Pro 
385                 390                 395                 400 


His Leu Val Asp Arg Thr Thr Ala Val Ala Arg Lys Thr Gly Phe Pro 
                405                 410                 415     


Glu Ile Ile Met Pro Gly Asp Val Arg Asn Asp Ile Tyr Val Thr Leu 
            420                 425                 430         


Val Gln Gly Asp Phe Asp Lys Gly Ser Lys Thr Thr Ala Lys Asn Val 
        435                 440                 445             


Glu Val Thr Val Ser Val Tyr Asp Glu Asp Gly Lys Arg Leu Glu His 
    450                 455                 460                 


Val Ile Phe Pro Gly Ala Gly Asp Glu Ala Ile Ser Glu Tyr Lys Ser 
465                 470                 475                 480 


Val Ile Tyr Tyr Gln Val Lys Gln Pro Arg Trp Phe Glu Thr Val Lys 
                485                 490                 495     


Val Ala Ile Pro Ile Glu Asp Val Asn Arg Ser His Leu Arg Phe Thr 
            500                 505                 510         


Phe Arg His Arg Ser Ser Gln Asp Ser Lys Asp Lys Ser Glu Lys Ile 
        515                 520                 525             


Phe Ala Leu Ala Phe Val Lys Leu Met Arg Tyr Asp Gly Thr Thr Leu 
    530                 535                 540                 


Arg Asp Gly Glu His Asp Leu Ile Val Tyr Lys Ala Glu Ala Lys Lys 
545                 550                 555                 560 


Leu Glu Asp Ala Ala Thr Tyr Leu Ser Leu Pro Ser Thr Lys Ala Glu 
                565                 570                 575     


Leu Glu Glu Lys Gly His Ser Ala Thr Gly Lys Ser Met Gln Ser Leu 
            580                 585                 590         


Gly Ser Cys Thr Ile Ser Lys Asp Ser Phe Gln Ile Ser Thr Leu Val 
        595                 600                 605             


Cys Ser Thr Lys Leu Thr Gln Asn Val Asp Leu Leu Gly Leu Leu Lys 
    610                 615                 620                 


Trp Arg Ser Asn Thr Ser Leu Leu Gln Gln Asn Leu Arg Gln Leu Met 
625                 630                 635                 640 


Lys Val Asp Gly Gly Glu Val Val Lys Phe Leu Gln Asp Thr Leu Asp 
                645                 650                 655     


Ala Leu Phe Asn Ile Met Met Glu Asn Ser Glu Ser Glu Thr Phe Asp 
            660                 665                 670         


Thr Leu Val Phe Asp Ala Leu Val Phe Ile Ile Gly Leu Ile Ala Asp 
        675                 680                 685             


Arg Lys Phe Gln His Phe Asn Pro Val Leu Glu Thr Tyr Ile Lys Lys 
    690                 695                 700                 


His Phe Ser Ala Thr Leu Ala Tyr Thr Lys Leu Thr Lys Val Leu Lys 
705                 710                 715                 720 


Asn Tyr Val Asp Gly Ala Glu Lys Pro Gly Val Asn Glu Gln Leu Tyr 
                725                 730                 735     


Lys Ala Met Lys Ala Leu Glu Ser Ile Phe Lys Phe Ile Val Arg Ser 
            740                 745                 750         


Arg Ile Leu Phe Asn Gln Leu Tyr Glu Asn Lys Gly Glu Ala Asp Phe 
        755                 760                 765             


Val Glu Ser Leu Leu Gln Leu Phe Arg Ser Ile Asn Asp Met Met Ser 
    770                 775                 780                 


Ser Met Ser Asp Gln Thr Val Arg Val Lys Gly Ala Ala Leu Lys Tyr 
785                 790                 795                 800 


Leu Pro Thr Ile Val Asn Asp Val Lys Leu Val Phe Asp Pro Lys Glu 
                805                 810                 815     


Leu Ser Lys Met Phe Thr Glu Phe Ile Leu Asn Val Pro Met Gly Leu 
            820                 825                 830         


Leu Thr Ile Gln Lys Leu Tyr Cys Leu Ile Glu Ile Val His Ser Asp 
        835                 840                 845             


Leu Phe Thr Gln His Asp Cys Arg Glu Ile Leu Leu Pro Met Met Thr 
    850                 855                 860                 


Asp Gln Leu Lys Tyr His Leu Glu Arg Gln Glu Asp Leu Glu Ala Cys 
865                 870                 875                 880 


Cys Gln Leu Leu Ser His Ile Leu Glu Val Leu Tyr Arg Lys Asp Val 
                885                 890                 895     


Gly Pro Thr Gln Arg His Val Gln Ile Ile Met Glu Lys Leu Leu Arg 
            900                 905                 910         


Thr Val Asn Arg Thr Val Ile Ser Met Gly Arg Asp Ser Glu Leu Ile 
        915                 920                 925             


Gly Asn Phe Val Ala Cys Met Thr Ala Ile Leu Arg Gln Met Glu Asp 
    930                 935                 940                 


Tyr His Tyr Ala His Leu Ile Lys Thr Phe Gly Lys Met Arg Thr Asp 
945                 950                 955                 960 


Val Val Asp Phe Leu Met Glu Thr Phe Ile Met Phe Lys Asn Leu Ile 
                965                 970                 975     


Gly Lys Asn Val Tyr Pro Phe Asp Trp Val Ile Met Asn Met Val Gln 
            980                 985                 990         


Asn Lys Val Phe Leu Arg Ala Ile  Asn Gln Tyr Ala Asp  Met Leu Asn 
        995                 1000                 1005             


Lys Lys  Phe Leu Asp Gln Ala  Asn Phe Glu Leu Gln  Leu Trp Asn 
    1010                 1015                 1020             


Asn Tyr  Phe His Leu Ala Val  Ala Phe Leu Thr Gln  Glu Ser Leu 
    1025                 1030                 1035             


Gln Leu  Glu Asn Phe Ser Ser  Ala Lys Arg Ala Lys  Ile Leu Asn 
    1040                 1045                 1050             


Lys Tyr  Gly Asp Met Arg Arg  Gln Ile Gly Phe Glu  Ile Arg Asp 
    1055                 1060                 1065             


Met Trp  Tyr Asn Leu Gly Gln  His Lys Ile Lys Phe  Ile Pro Glu 
    1070                 1075                 1080             


Met Val  Gly Pro Ile Leu Glu  Met Thr Leu Ile Pro  Glu Thr Glu 
    1085                 1090                 1095             


Leu Arg  Lys Ala Thr Ile Pro  Ile Phe Phe Asp Met  Met Gln Cys 
    1100                 1105                 1110             


Glu Phe  His Ser Thr Arg Ser  Phe Gln Met Phe Glu  Asn Glu Ile 
    1115                 1120                 1125             


Ile Thr  Lys Leu Asp His Glu  Val Glu Gly Gly Arg  Gly Asp Glu 
    1130                 1135                 1140             


Gln Tyr  Lys Val Leu Phe Asp  Lys Ile Leu Leu Glu  His Cys Arg 
    1145                 1150                 1155             


Lys His  Lys Tyr Leu Ala Lys  Thr Gly Glu Thr Phe  Val Lys Leu 
    1160                 1165                 1170             


Val Val  Arg Leu Met Glu Arg  Leu Leu Asp Tyr Arg  Thr Ile Met 
    1175                 1180                 1185             


His Asp  Glu Asn Lys Glu Asn  Arg Met Ser Cys Thr  Val Asn Val 
    1190                 1195                 1200             


Leu Asn  Phe Tyr Lys Glu Ile  Glu Arg Glu Glu Met  Tyr Ile Arg 
    1205                 1210                 1215             


Tyr Leu  Tyr Lys Leu Cys Asp  Leu His Lys Glu Cys  Asp Asn Tyr 
    1220                 1225                 1230             


Thr Glu  Ala Ala Tyr Thr Leu  Leu Leu His Ala Lys  Leu Leu Lys 
    1235                 1240                 1245             


Trp Ser  Glu Asp Val Cys Val  Ala His Leu Thr Gln  Arg Asp Gly 
    1250                 1255                 1260             


Tyr Gln  Ala Thr Thr Gln Gly  Gln Leu Lys Glu Gln  Leu Tyr Gln 
    1265                 1270                 1275             


Glu Ile  Ile His Tyr Phe Asp  Lys Gly Lys Met Trp  Glu Glu Ala 
    1280                 1285                 1290             


Ile Ala  Leu Gly Lys Glu Leu  Ala Glu Gln Tyr Glu  Asn Glu Met 
    1295                 1300                 1305             


Phe Asp  Tyr Glu Gln Leu Ser  Glu Leu Leu Lys Lys  Gln Ala Gln 
    1310                 1315                 1320             


Phe Tyr  Glu Asn Ile Val Lys  Val Ile Arg Pro Lys  Pro Asp Tyr 
    1325                 1330                 1335             


Phe Ala  Val Gly Tyr Tyr Gly  Gln Gly Phe Pro Thr  Phe Leu Arg 
    1340                 1345                 1350             


Gly Lys  Val Phe Ile Tyr Arg  Gly Lys Glu Tyr Glu  Arg Arg Glu 
    1355                 1360                 1365             


Asp Phe  Glu Ala Arg Leu Leu  Thr Gln Phe Pro Asn  Ala Glu Lys 
    1370                 1375                 1380             


Met Lys  Thr Thr Ser Pro Pro  Gly Asp Asp Ile Lys  Asn Ser Pro 
    1385                 1390                 1395             


Gly Gln  Tyr Ile Gln Cys Phe  Thr Val Lys Pro Lys  Leu Asp Leu 
    1400                 1405                 1410             


Pro Pro  Lys Phe His Arg Pro  Val Ser Glu Gln Ile  Val Ser Phe 
    1415                 1420                 1425             


Tyr Arg  Val Asn Glu Val Gln  Arg Phe Glu Tyr Ser  Arg Pro Ile 
    1430                 1435                 1440             


Arg Lys  Gly Glu Lys Asn Pro  Asp Asn Glu Phe Ala  Asn Met Trp 
    1445                 1450                 1455             


Ile Glu  Arg Thr Ile Tyr Thr  Thr Ala Tyr Lys Leu  Pro Gly Ile 
    1460                 1465                 1470             


Leu Arg  Trp Phe Glu Val Lys  Ser Val Phe Met Val  Glu Ile Ser 
    1475                 1480                 1485             


Pro Leu  Glu Asn Ala Ile Glu  Thr Met Gln Leu Thr  Asn Asp Lys 
    1490                 1495                 1500             


Ile Asn  Ser Met Val Gln Gln  His Leu Asp Asp Pro  Ser Leu Pro 
    1505                 1510                 1515             


Ile Asn  Pro Leu Ser Met Leu  Leu Asn Gly Ile Val  Asp Pro Ala 
    1520                 1525                 1530             


Val Met  Gly Gly Phe Ala Asn  Tyr Glu Lys Ala Phe  Phe Thr Asp 
    1535                 1540                 1545             


Arg Tyr  Leu Gln Glu His Pro  Glu Ala His Glu Lys  Ile Glu Lys 
    1550                 1555                 1560             


Leu Lys  Asp Leu Ile Ala Trp  Gln Ile Pro Phe Leu  Ala Glu Gly 
    1565                 1570                 1575             


Ile Arg  Ile His Gly Asp Lys  Val Thr Glu Ala Leu  Arg Pro Phe 
    1580                 1585                 1590             


His Glu  Arg Met Glu Ala Cys  Phe Lys Gln Leu Lys  Glu Lys Val 
    1595                 1600                 1605             


Glu Lys  Glu Tyr Gly Val Arg  Ile Met Pro Ser Ser  Leu Asp Asp 
    1610                 1615                 1620             


Arg Arg  Gly Ser Arg Pro Arg  Ser Met Val Arg Ser  Phe Thr Met 
    1625                 1630                 1635             


Pro Ser  Ser Ser Arg Pro Leu  Ser Val Ala Ser Val  Ser Ser Leu 
    1640                 1645                 1650             


Ser Ser  Asp Ser Thr Pro Ser  Arg Pro Gly Ser Asp  Gly Phe Ala 
    1655                 1660                 1665             


Leu Glu  Pro Leu Leu Pro Lys  Lys Met His Ser Arg  Ser Gln Asp 
    1670                 1675                 1680             


Lys Leu  Asp Lys Asp Asp Leu  Glu Lys Glu Lys Lys  Asp Lys Lys 
    1685                 1690                 1695             


Lys Glu  Lys Arg Asn Ser Lys  His Gln Glu Ile Phe  Glu Lys Glu 
    1700                 1705                 1710             


Phe Lys  Pro Thr Asp Ile Ser  Leu Gln Gln Ser Glu  Ala Val Ile 
    1715                 1720                 1725             


Leu Ser  Glu Thr Ile Ser Pro  Leu Arg Pro Gln Arg  Pro Lys Ser 
    1730                 1735                 1740             


Gln Val  Met Asn Val Ile Gly  Ser Glu Arg Arg Phe  Ser Val Ser 
    1745                 1750                 1755             


Pro Ser  Ser Pro Ser Ser Gln  Gln Thr Pro Pro Pro  Val Thr Pro 
    1760                 1765                 1770             


Arg Ala  Lys Leu Ser Phe Ser  Met Gln Ser Ser Leu  Glu Leu Asn 
    1775                 1780                 1785             


Gly Met  Thr Gly Ala Asp Val  Ala Asp Val Pro Pro  Pro Leu Pro 
    1790                 1795                 1800             


Leu Lys  Gly Ser Val Ala Asp  Tyr Gly Asn Leu Met  Glu Asn Gln 
    1805                 1810                 1815             


Asp Leu  Leu Gly Ser Pro Thr  Pro Pro Pro Pro Pro  Pro His Gln 
    1820                 1825                 1830             


Arg His  Leu Pro Pro Pro Leu  Pro Ser Lys Thr Pro  Pro Pro Pro 
    1835                 1840                 1845             


Pro Pro  Lys Thr Thr Arg Lys  Gln Thr Ser Val Asp  Ser Gly Ile 
    1850                 1855                 1860             


Val Gln  
    1865 


<210>  3685
<211>  785
<212>  PRT
<213>  homo sapiens

<400>  3685

Met Ser Asp Gln Asp His Ser Met Asp Glu Met Thr Ala Val Val Lys 
1               5                   10                  15      


Ile Glu Lys Gly Val Gly Gly Asn Asn Gly Gly Asn Gly Asn Gly Gly 
            20                  25                  30          


Gly Ala Phe Ser Gln Ala Arg Ser Ser Ser Thr Gly Ser Ser Ser Ser 
        35                  40                  45              


Thr Gly Gly Gly Gly Gln Glu Ser Gln Pro Ser Pro Leu Ala Leu Leu 
    50                  55                  60                  


Ala Ala Thr Cys Ser Arg Ile Glu Ser Pro Asn Glu Asn Ser Asn Asn 
65                  70                  75                  80  


Ser Gln Gly Pro Ser Gln Ser Gly Gly Thr Gly Glu Leu Asp Leu Thr 
                85                  90                  95      


Ala Thr Gln Leu Ser Gln Gly Ala Asn Gly Trp Gln Ile Ile Ser Ser 
            100                 105                 110         


Ser Ser Gly Ala Thr Pro Thr Ser Lys Glu Gln Ser Gly Ser Ser Thr 
        115                 120                 125             


Asn Gly Ser Asn Gly Ser Glu Ser Ser Lys Asn Arg Thr Val Ser Gly 
    130                 135                 140                 


Gly Gln Tyr Val Val Ala Ala Ala Pro Asn Leu Gln Asn Gln Gln Val 
145                 150                 155                 160 


Leu Thr Gly Leu Pro Gly Val Met Pro Asn Ile Gln Tyr Gln Val Ile 
                165                 170                 175     


Pro Gln Phe Gln Thr Val Asp Gly Gln Gln Leu Gln Phe Ala Ala Thr 
            180                 185                 190         


Gly Ala Gln Val Gln Gln Asp Gly Ser Gly Gln Ile Gln Ile Ile Pro 
        195                 200                 205             


Gly Ala Asn Gln Gln Ile Ile Thr Asn Arg Gly Ser Gly Gly Asn Ile 
    210                 215                 220                 


Ile Ala Ala Met Pro Asn Leu Leu Gln Gln Ala Val Pro Leu Gln Gly 
225                 230                 235                 240 


Leu Ala Asn Asn Val Leu Ser Gly Gln Thr Gln Tyr Val Thr Asn Val 
                245                 250                 255     


Pro Val Ala Leu Asn Gly Asn Ile Thr Leu Leu Pro Val Asn Ser Val 
            260                 265                 270         


Ser Ala Ala Thr Leu Thr Pro Ser Ser Gln Ala Val Thr Ile Ser Ser 
        275                 280                 285             


Ser Gly Ser Gln Glu Ser Gly Ser Gln Pro Val Thr Ser Gly Thr Thr 
    290                 295                 300                 


Ile Ser Ser Ala Ser Leu Val Ser Ser Gln Ala Ser Ser Ser Ser Phe 
305                 310                 315                 320 


Phe Thr Asn Ala Asn Ser Tyr Ser Thr Thr Thr Thr Thr Ser Asn Met 
                325                 330                 335     


Gly Ile Met Asn Phe Thr Thr Ser Gly Ser Ser Gly Thr Asn Ser Gln 
            340                 345                 350         


Gly Gln Thr Pro Gln Arg Val Ser Gly Leu Gln Gly Ser Asp Ala Leu 
        355                 360                 365             


Asn Ile Gln Gln Asn Gln Thr Ser Gly Gly Ser Leu Gln Ala Gly Gln 
    370                 375                 380                 


Gln Lys Glu Gly Glu Gln Asn Gln Gln Thr Gln Gln Gln Gln Ile Leu 
385                 390                 395                 400 


Ile Gln Pro Gln Leu Val Gln Gly Gly Gln Ala Leu Gln Ala Leu Gln 
                405                 410                 415     


Ala Ala Pro Leu Ser Gly Gln Thr Phe Thr Thr Gln Ala Ile Ser Gln 
            420                 425                 430         


Glu Thr Leu Gln Asn Leu Gln Leu Gln Ala Val Pro Asn Ser Gly Pro 
        435                 440                 445             


Ile Ile Ile Arg Thr Pro Thr Val Gly Pro Asn Gly Gln Val Ser Trp 
    450                 455                 460                 


Gln Thr Leu Gln Leu Gln Asn Leu Gln Val Gln Asn Pro Gln Ala Gln 
465                 470                 475                 480 


Thr Ile Thr Leu Ala Pro Met Gln Gly Val Ser Leu Gly Gln Thr Ser 
                485                 490                 495     


Ser Ser Asn Thr Thr Leu Thr Pro Ile Ala Ser Ala Ala Ser Ile Pro 
            500                 505                 510         


Ala Gly Thr Val Thr Val Asn Ala Ala Gln Leu Ser Ser Met Pro Gly 
        515                 520                 525             


Leu Gln Thr Ile Asn Leu Ser Ala Leu Gly Thr Ser Gly Ile Gln Val 
    530                 535                 540                 


His Pro Ile Gln Gly Leu Pro Leu Ala Ile Ala Asn Ala Pro Gly Asp 
545                 550                 555                 560 


His Gly Ala Gln Leu Gly Leu His Gly Ala Gly Gly Asp Gly Ile His 
                565                 570                 575     


Asp Asp Thr Ala Gly Gly Glu Glu Gly Glu Asn Ser Pro Asp Ala Gln 
            580                 585                 590         


Pro Gln Ala Gly Arg Arg Thr Arg Arg Glu Ala Cys Thr Cys Pro Tyr 
        595                 600                 605             


Cys Lys Asp Ser Glu Gly Arg Gly Ser Gly Asp Pro Gly Lys Lys Lys 
    610                 615                 620                 


Gln His Ile Cys His Ile Gln Gly Cys Gly Lys Val Tyr Gly Lys Thr 
625                 630                 635                 640 


Ser His Leu Arg Ala His Leu Arg Trp His Thr Gly Glu Arg Pro Phe 
                645                 650                 655     


Met Cys Thr Trp Ser Tyr Cys Gly Lys Arg Phe Thr Arg Ser Asp Glu 
            660                 665                 670         


Leu Gln Arg His Lys Arg Thr His Thr Gly Glu Lys Lys Phe Ala Cys 
        675                 680                 685             


Pro Glu Cys Pro Lys Arg Phe Met Arg Ser Asp His Leu Ser Lys His 
    690                 695                 700                 


Ile Lys Thr His Gln Asn Lys Lys Gly Gly Pro Gly Val Ala Leu Ser 
705                 710                 715                 720 


Val Gly Thr Leu Pro Leu Asp Ser Gly Ala Gly Ser Glu Gly Ser Gly 
                725                 730                 735     


Thr Ala Thr Pro Ser Ala Leu Ile Thr Thr Asn Met Val Ala Met Glu 
            740                 745                 750         


Ala Ile Cys Pro Glu Gly Ile Ala Arg Leu Ala Asn Ser Gly Ile Asn 
        755                 760                 765             


Val Met Gln Val Ala Asp Leu Gln Ser Ile Asn Ile Ser Gly Asn Gly 
    770                 775                 780                 


Phe 
785 


<210>  3686
<211>  306
<212>  PRT
<213>  homo sapiens

<400>  3686

Met Ala Ser Pro Gly Cys Leu Trp Leu Leu Ala Val Ala Leu Leu Pro 
1               5                   10                  15      


Trp Thr Cys Ala Ser Arg Ala Leu Gln His Leu Asp Pro Pro Ala Pro 
            20                  25                  30          


Leu Pro Leu Val Ile Trp His Gly Met Gly Asp Ser Cys Cys Asn Pro 
        35                  40                  45              


Leu Ser Met Gly Ala Ile Lys Lys Met Val Glu Lys Lys Ile Pro Gly 
    50                  55                  60                  


Ile Tyr Val Leu Ser Leu Glu Ile Gly Lys Thr Leu Met Glu Asp Val 
65                  70                  75                  80  


Glu Asn Ser Phe Phe Leu Asn Val Asn Ser Gln Val Thr Thr Val Cys 
                85                  90                  95      


Gln Ala Leu Ala Lys Asp Pro Lys Leu Gln Gln Gly Tyr Asn Ala Met 
            100                 105                 110         


Gly Phe Ser Gln Gly Gly Gln Phe Leu Arg Ala Val Ala Gln Arg Cys 
        115                 120                 125             


Pro Ser Pro Pro Met Ile Asn Leu Ile Ser Val Gly Gly Gln His Gln 
    130                 135                 140                 


Gly Val Phe Gly Leu Pro Arg Cys Pro Gly Glu Ser Ser His Ile Cys 
145                 150                 155                 160 


Asp Phe Ile Arg Lys Thr Leu Asn Ala Gly Ala Tyr Ser Lys Val Val 
                165                 170                 175     


Gln Glu Arg Leu Val Gln Ala Glu Tyr Trp His Asp Pro Ile Lys Glu 
            180                 185                 190         


Asp Val Tyr Arg Asn His Ser Ile Phe Leu Ala Asp Ile Asn Gln Glu 
        195                 200                 205             


Arg Gly Ile Asn Glu Ser Tyr Lys Lys Asn Leu Met Ala Leu Lys Lys 
    210                 215                 220                 


Phe Val Met Val Lys Phe Leu Asn Asp Ser Ile Val Asp Pro Val Asp 
225                 230                 235                 240 


Ser Glu Trp Phe Gly Phe Tyr Arg Ser Gly Gln Ala Lys Glu Thr Ile 
                245                 250                 255     


Pro Leu Gln Glu Thr Ser Leu Tyr Thr Gln Asp Arg Leu Gly Leu Lys 
            260                 265                 270         


Glu Met Asp Asn Ala Gly Gln Leu Val Phe Leu Ala Thr Glu Gly Asp 
        275                 280                 285             


His Leu Gln Leu Ser Glu Glu Trp Phe Tyr Ala His Ile Ile Pro Phe 
    290                 295                 300                 


Leu Gly 
305     


<210>  3687
<211>  203
<212>  PRT
<213>  homo sapiens

<400>  3687

Met Ala Ser Pro Gly Cys Leu Trp Leu Leu Ala Val Ala Leu Leu Pro 
1               5                   10                  15      


Trp Thr Cys Ala Ser Arg Ala Leu Gln His Leu Asp Pro Pro Ala Pro 
            20                  25                  30          


Leu Pro Leu Val Ile Trp His Gly Met Gly Val Phe Gly Leu Pro Arg 
        35                  40                  45              


Cys Pro Gly Glu Ser Ser His Ile Cys Asp Phe Ile Arg Lys Thr Leu 
    50                  55                  60                  


Asn Ala Gly Ala Tyr Ser Lys Val Val Gln Glu Arg Leu Val Gln Ala 
65                  70                  75                  80  


Glu Tyr Trp His Asp Pro Ile Lys Glu Asp Val Tyr Arg Asn His Ser 
                85                  90                  95      


Ile Phe Leu Ala Asp Ile Asn Gln Glu Arg Gly Ile Asn Glu Ser Tyr 
            100                 105                 110         


Lys Lys Asn Leu Met Ala Leu Lys Lys Phe Val Met Val Lys Phe Leu 
        115                 120                 125             


Asn Asp Ser Ile Val Asp Pro Val Asp Ser Glu Trp Phe Gly Phe Tyr 
    130                 135                 140                 


Arg Ser Gly Gln Ala Lys Glu Thr Ile Pro Leu Gln Glu Thr Ser Leu 
145                 150                 155                 160 


Tyr Thr Gln Asp Arg Leu Gly Leu Lys Glu Met Asp Asn Ala Gly Gln 
                165                 170                 175     


Leu Val Phe Leu Ala Thr Glu Gly Asp His Leu Gln Leu Ser Glu Glu 
            180                 185                 190         


Trp Phe Tyr Ala His Ile Ile Pro Phe Leu Gly 
        195                 200             


<210>  3688
<211>  1690
<212>  PRT
<213>  homo sapiens

<400>  3688

Met Ala Gly Val Gly Pro Gly Gly Tyr Ala Ala Glu Phe Val Pro Pro 
1               5                   10                  15      


Pro Glu Cys Pro Val Phe Glu Pro Ser Trp Glu Glu Phe Thr Asp Pro 
            20                  25                  30          


Leu Ser Phe Ile Gly Arg Ile Arg Pro Leu Ala Glu Lys Thr Gly Ile 
        35                  40                  45              


Cys Lys Ile Arg Pro Pro Lys Asp Trp Gln Pro Pro Phe Ala Cys Glu 
    50                  55                  60                  


Val Lys Ser Phe Arg Phe Thr Pro Arg Val Gln Arg Leu Asn Glu Leu 
65                  70                  75                  80  


Glu Ala Met Thr Arg Val Arg Leu Asp Phe Leu Asp Gln Leu Ala Lys 
                85                  90                  95      


Phe Trp Glu Leu Gln Gly Ser Thr Leu Lys Ile Pro Val Val Glu Arg 
            100                 105                 110         


Lys Ile Leu Asp Leu Tyr Ala Leu Ser Lys Ile Val Ala Ser Lys Gly 
        115                 120                 125             


Gly Phe Glu Met Val Thr Lys Glu Lys Lys Trp Ser Lys Val Gly Ser 
    130                 135                 140                 


Arg Leu Gly Tyr Leu Pro Gly Lys Gly Thr Gly Ser Leu Leu Lys Ser 
145                 150                 155                 160 


His Tyr Glu Arg Ile Leu Tyr Pro Tyr Glu Leu Phe Gln Ser Gly Val 
                165                 170                 175     


Ser Leu Met Gly Val Gln Met Pro Asn Leu Asp Leu Lys Glu Lys Val 
            180                 185                 190         


Glu Pro Glu Val Leu Ser Thr Asp Thr Gln Thr Ser Pro Glu Pro Gly 
        195                 200                 205             


Thr Arg Met Asn Ile Leu Pro Lys Arg Thr Arg Arg Val Lys Thr Gln 
    210                 215                 220                 


Ser Glu Ser Gly Asp Val Ser Arg Asn Thr Glu Leu Lys Lys Leu Gln 
225                 230                 235                 240 


Ile Phe Gly Ala Gly Pro Lys Val Val Gly Leu Ala Met Gly Thr Lys 
                245                 250                 255     


Asp Lys Glu Asp Glu Val Thr Arg Arg Arg Lys Val Thr Asn Arg Ser 
            260                 265                 270         


Asp Ala Phe Asn Met Gln Met Arg Gln Arg Lys Gly Thr Leu Ser Val 
        275                 280                 285             


Asn Phe Val Asp Leu Tyr Val Cys Met Phe Cys Gly Arg Gly Asn Asn 
    290                 295                 300                 


Glu Asp Lys Leu Leu Leu Cys Asp Gly Cys Asp Asp Ser Tyr His Thr 
305                 310                 315                 320 


Phe Cys Leu Ile Pro Pro Leu Pro Asp Val Pro Lys Gly Asp Trp Arg 
                325                 330                 335     


Cys Pro Lys Cys Val Ala Glu Glu Cys Ser Lys Pro Arg Glu Ala Phe 
            340                 345                 350         


Gly Phe Glu Gln Ala Val Arg Glu Tyr Thr Leu Gln Ser Phe Gly Glu 
        355                 360                 365             


Met Ala Asp Asn Phe Lys Ser Asp Tyr Phe Asn Met Pro Val His Met 
    370                 375                 380                 


Val Pro Thr Glu Leu Val Glu Lys Glu Phe Trp Arg Leu Val Ser Ser 
385                 390                 395                 400 


Ile Glu Glu Asp Val Ile Val Glu Tyr Gly Ala Asp Ile Ser Ser Lys 
                405                 410                 415     


Asp Phe Gly Ser Gly Phe Pro Val Lys Asp Gly Arg Arg Lys Ile Leu 
            420                 425                 430         


Pro Glu Glu Glu Glu Tyr Ala Leu Ser Gly Trp Asn Leu Asn Asn Met 
        435                 440                 445             


Pro Val Leu Glu Gln Ser Val Leu Ala His Ile Asn Val Asp Ile Ser 
    450                 455                 460                 


Gly Met Lys Val Pro Trp Leu Tyr Val Gly Met Cys Phe Ser Ser Phe 
465                 470                 475                 480 


Cys Trp His Ile Glu Asp His Trp Ser Tyr Ser Ile Asn Tyr Leu His 
                485                 490                 495     


Trp Gly Glu Pro Lys Thr Trp Tyr Gly Val Pro Ser His Ala Ala Glu 
            500                 505                 510         


Gln Leu Glu Glu Val Met Arg Glu Leu Ala Pro Glu Leu Phe Glu Ser 
        515                 520                 525             


Gln Pro Asp Leu Leu His Gln Leu Val Thr Ile Met Asn Pro Asn Val 
    530                 535                 540                 


Leu Met Glu His Gly Val Pro Val Tyr Arg Thr Asn Gln Cys Ala Gly 
545                 550                 555                 560 


Glu Phe Val Val Thr Phe Pro Arg Ala Tyr His Ser Gly Phe Asn Gln 
                565                 570                 575     


Gly Tyr Asn Phe Ala Glu Ala Val Asn Phe Cys Thr Ala Asp Trp Leu 
            580                 585                 590         


Pro Ile Gly Arg Gln Cys Val Asn His Tyr Arg Arg Leu Arg Arg His 
        595                 600                 605             


Cys Val Phe Ser His Glu Glu Leu Ile Phe Lys Met Ala Ala Asp Pro 
    610                 615                 620                 


Glu Cys Leu Asp Val Gly Leu Ala Ala Met Val Cys Lys Glu Leu Thr 
625                 630                 635                 640 


Leu Met Thr Glu Glu Glu Thr Arg Leu Arg Glu Ser Val Val Gln Met 
                645                 650                 655     


Gly Val Leu Met Ser Glu Glu Glu Val Phe Glu Leu Val Pro Asp Asp 
            660                 665                 670         


Glu Arg Gln Cys Ser Ala Cys Arg Thr Thr Cys Phe Leu Ser Ala Leu 
        675                 680                 685             


Thr Cys Ser Cys Asn Pro Glu Arg Leu Val Cys Leu Tyr His Pro Thr 
    690                 695                 700                 


Asp Leu Cys Pro Cys Pro Met Gln Lys Lys Cys Leu Arg Tyr Arg Tyr 
705                 710                 715                 720 


Pro Leu Glu Asp Leu Pro Ser Leu Leu Tyr Gly Val Lys Val Arg Ala 
                725                 730                 735     


Gln Ser Tyr Asp Thr Trp Val Ser Arg Val Thr Glu Ala Leu Ser Ala 
            740                 745                 750         


Asn Phe Asn His Lys Lys Asp Leu Ile Glu Leu Arg Val Met Leu Glu 
        755                 760                 765             


Asp Ala Glu Asp Arg Lys Tyr Pro Glu Asn Asp Leu Phe Arg Lys Leu 
    770                 775                 780                 


Arg Asp Ala Val Lys Glu Ala Glu Thr Cys Ala Ser Val Ala Gln Leu 
785                 790                 795                 800 


Leu Leu Ser Lys Lys Gln Lys His Arg Gln Ser Pro Asp Ser Gly Arg 
                805                 810                 815     


Thr Arg Thr Lys Leu Thr Val Glu Glu Leu Lys Ala Phe Val Gln Gln 
            820                 825                 830         


Leu Phe Ser Leu Pro Cys Val Ile Ser Gln Ala Arg Gln Val Lys Asn 
        835                 840                 845             


Leu Leu Asp Asp Val Glu Glu Phe His Glu Arg Ala Gln Glu Ala Met 
    850                 855                 860                 


Met Asp Glu Thr Pro Asp Ser Ser Lys Leu Gln Met Leu Ile Asp Met 
865                 870                 875                 880 


Gly Ser Ser Leu Tyr Val Glu Leu Pro Glu Leu Pro Arg Leu Lys Gln 
                885                 890                 895     


Glu Leu Gln Gln Ala Arg Trp Leu Asp Glu Val Arg Leu Thr Leu Ser 
            900                 905                 910         


Asp Pro Gln Gln Val Thr Leu Asp Val Met Lys Lys Leu Ile Asp Ser 
        915                 920                 925             


Gly Val Gly Leu Ala Pro His His Ala Val Glu Lys Ala Met Ala Glu 
    930                 935                 940                 


Leu Gln Glu Leu Leu Thr Val Ser Glu Arg Trp Glu Glu Lys Ala Lys 
945                 950                 955                 960 


Val Cys Leu Gln Ala Arg Pro Arg His Ser Val Ala Ser Leu Glu Ser 
                965                 970                 975     


Ile Val Asn Glu Ala Lys Asn Ile Pro Ala Phe Leu Pro Asn Val Leu 
            980                 985                 990         


Ser Leu Lys Glu Ala Leu Gln Lys  Ala Arg Glu Trp Thr  Ala Lys Val 
        995                 1000                 1005             


Glu Ala  Ile Gln Ser Gly Ser  Asn Tyr Ala Tyr Leu  Glu Gln Leu 
    1010                 1015                 1020             


Glu Ser  Leu Ser Ala Lys Gly  Arg Pro Ile Pro Val  Arg Leu Glu 
    1025                 1030                 1035             


Ala Leu  Pro Gln Val Glu Ser  Gln Val Ala Ala Ala  Arg Ala Trp 
    1040                 1045                 1050             


Arg Glu  Arg Thr Gly Arg Thr  Phe Leu Lys Lys Asn  Ser Ser His 
    1055                 1060                 1065             


Thr Leu  Leu Gln Val Leu Ser  Pro Arg Thr Asp Ile  Gly Val Tyr 
    1070                 1075                 1080             


Gly Ser  Gly Lys Asn Arg Arg  Lys Lys Val Lys Glu  Leu Ile Glu 
    1085                 1090                 1095             


Lys Glu  Lys Glu Lys Asp Leu  Asp Leu Glu Pro Leu  Ser Asp Leu 
    1100                 1105                 1110             


Glu Glu  Gly Leu Glu Glu Thr  Arg Asp Thr Ala Met  Val Val Ala 
    1115                 1120                 1125             


Val Phe  Lys Glu Arg Glu Gln  Lys Glu Ile Glu Ala  Met His Ser 
    1130                 1135                 1140             


Leu Arg  Ala Ala Asn Leu Ala  Lys Met Thr Met Val  Asp Arg Ile 
    1145                 1150                 1155             


Glu Glu  Val Lys Phe Cys Ile  Cys Arg Lys Thr Ala  Ser Gly Phe 
    1160                 1165                 1170             


Met Leu  Gln Cys Glu Leu Cys  Lys Asp Trp Phe His  Asn Ser Cys 
    1175                 1180                 1185             


Val Pro  Leu Pro Lys Ser Ser  Ser Gln Lys Lys Gly  Ser Ser Trp 
    1190                 1195                 1200             


Gln Ala  Lys Glu Val Lys Phe  Leu Cys Pro Leu Cys  Met Arg Ser 
    1205                 1210                 1215             


Arg Arg  Pro Arg Leu Glu Thr  Ile Leu Ser Leu Leu  Val Ser Leu 
    1220                 1225                 1230             


Gln Lys  Leu Pro Val Arg Leu  Pro Glu Gly Glu Ala  Leu Gln Cys 
    1235                 1240                 1245             


Leu Thr  Glu Arg Ala Met Ser  Trp Gln Asp Arg Ala  Arg Gln Ala 
    1250                 1255                 1260             


Leu Ala  Thr Asp Glu Leu Ser  Ser Ala Leu Ala Lys  Leu Ser Val 
    1265                 1270                 1275             


Leu Ser  Gln Arg Met Val Glu  Gln Ala Ala Arg Glu  Lys Thr Glu 
    1280                 1285                 1290             


Lys Ile  Ile Ser Ala Glu Leu  Gln Lys Ala Ala Ala  Asn Pro Asp 
    1295                 1300                 1305             


Leu Gln  Gly His Leu Pro Ser  Phe Gln Gln Ser Ala  Phe Asn Arg 
    1310                 1315                 1320             


Val Val  Ser Ser Val Ser Ser  Ser Pro Arg Gln Thr  Met Asp Tyr 
    1325                 1330                 1335             


Asp Asp  Glu Glu Thr Asp Ser  Asp Glu Asp Ile Arg  Glu Thr Tyr 
    1340                 1345                 1350             


Gly Tyr  Asp Met Lys Asp Thr  Ala Ser Val Lys Ser  Ser Ser Ser 
    1355                 1360                 1365             


Leu Glu  Pro Asn Leu Phe Cys  Asp Glu Glu Ile Pro  Ile Lys Ser 
    1370                 1375                 1380             


Glu Glu  Val Val Thr His Met  Trp Thr Ala Pro Ser  Phe Cys Ala 
    1385                 1390                 1395             


Glu His  Ala Tyr Ser Ser Ala  Ser Lys Ser Cys Ser  Gln Gly Ser 
    1400                 1405                 1410             


Ser Thr  Pro Arg Lys Gln Pro  Arg Lys Ser Pro Leu  Val Pro Arg 
    1415                 1420                 1425             


Ser Leu  Glu Pro Pro Val Leu  Glu Leu Ser Pro Gly  Ala Lys Ala 
    1430                 1435                 1440             


Gln Leu  Glu Glu Leu Met Met  Val Gly Asp Leu Leu  Glu Val Ser 
    1445                 1450                 1455             


Leu Asp  Glu Thr Gln His Ile  Trp Arg Ile Leu Gln  Ala Thr His 
    1460                 1465                 1470             


Pro Pro  Ser Glu Asp Arg Phe  Leu His Ile Met Glu  Asp Asp Ser 
    1475                 1480                 1485             


Met Glu  Glu Lys Pro Leu Lys  Val Lys Gly Lys Asp  Ser Ser Glu 
    1490                 1495                 1500             


Lys Lys  Arg Lys Arg Lys Leu  Glu Lys Val Glu Gln  Leu Phe Gly 
    1505                 1510                 1515             


Glu Gly  Lys Gln Lys Ser Lys  Glu Leu Lys Lys Met  Asp Lys Pro 
    1520                 1525                 1530             


Arg Lys  Lys Lys Leu Lys Leu  Gly Ala Asp Lys Ser  Lys Glu Leu 
    1535                 1540                 1545             


Asn Lys  Leu Ala Lys Lys Leu  Ala Lys Glu Glu Glu  Arg Lys Lys 
    1550                 1555                 1560             


Lys Lys  Glu Lys Ala Ala Ala  Ala Lys Val Glu Leu  Val Lys Glu 
    1565                 1570                 1575             


Ser Thr  Glu Lys Lys Arg Glu  Lys Lys Val Leu Asp  Ile Pro Ser 
    1580                 1585                 1590             


Lys Tyr  Asp Trp Ser Gly Ala  Glu Glu Ser Asp Asp  Glu Asn Ala 
    1595                 1600                 1605             


Val Cys  Ala Ala Gln Asn Cys  Gln Arg Pro Cys Lys  Asp Lys Val 
    1610                 1615                 1620             


Asp Trp  Val Gln Cys Asp Gly  Gly Cys Asp Glu Trp  Phe His Gln 
    1625                 1630                 1635             


Val Cys  Val Gly Val Ser Pro  Glu Met Ala Glu Asn  Glu Asp Tyr 
    1640                 1645                 1650             


Ile Cys  Ile Asn Cys Ala Lys  Lys Gln Gly Pro Val  Ser Pro Gly 
    1655                 1660                 1665             


Pro Ala  Pro Pro Pro Ser Phe  Ile Met Ser Tyr Lys  Leu Pro Met 
    1670                 1675                 1680             


Glu Asp  Leu Lys Glu Thr Ser  
    1685                 1690 


<210>  3689
<211>  200
<212>  PRT
<213>  homo sapiens

<400>  3689

Met Ala Lys Gly Asp Pro Lys Lys Pro Lys Gly Lys Met Ser Ala Tyr 
1               5                   10                  15      


Ala Phe Phe Val Gln Thr Cys Arg Glu Glu His Lys Lys Lys Asn Pro 
            20                  25                  30          


Glu Val Pro Val Asn Phe Ala Glu Phe Ser Lys Lys Cys Ser Glu Arg 
        35                  40                  45              


Trp Lys Thr Met Ser Gly Lys Glu Lys Ser Lys Phe Asp Glu Met Ala 
    50                  55                  60                  


Lys Ala Asp Lys Val Arg Tyr Asp Arg Glu Met Lys Asp Tyr Gly Pro 
65                  70                  75                  80  


Ala Lys Gly Gly Lys Lys Lys Lys Asp Pro Asn Ala Pro Lys Arg Pro 
                85                  90                  95      


Pro Ser Gly Phe Phe Leu Phe Cys Ser Glu Phe Arg Pro Lys Ile Lys 
            100                 105                 110         


Ser Thr Asn Pro Gly Ile Ser Ile Gly Asp Val Ala Lys Lys Leu Gly 
        115                 120                 125             


Glu Met Trp Asn Asn Leu Asn Asp Ser Glu Lys Gln Pro Tyr Ile Thr 
    130                 135                 140                 


Lys Ala Ala Lys Leu Lys Glu Lys Tyr Glu Lys Asp Val Ala Asp Tyr 
145                 150                 155                 160 


Lys Ser Lys Gly Lys Phe Asp Gly Ala Lys Gly Pro Ala Lys Val Ala 
                165                 170                 175     


Arg Lys Lys Val Glu Glu Glu Asp Glu Glu Glu Glu Glu Glu Glu Glu 
            180                 185                 190         


Glu Glu Glu Glu Glu Glu Asp Glu 
        195                 200 


<210>  3690
<211>  371
<212>  PRT
<213>  homo sapiens

<400>  3690

Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Pro Gly Gln Thr Pro Glu Ala Ala Lys Glu Ala Glu Leu Ala Ala Arg 
            20                  25                  30          


Ile Leu Leu Asp Gln Gly Gln Thr His Ser Val Glu Thr Pro Tyr Gly 
        35                  40                  45              


Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg Pro Ala 
    50                  55                  60                  


Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys Phe Gln 
65                  70                  75                  80  


Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn Phe Val 
                85                  90                  95      


Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro Val Phe 
            100                 105                 110         


Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp Met Ile 
        115                 120                 125             


Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly Val Gly 
    130                 135                 140                 


Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn His Pro 
145                 150                 155                 160 


Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn Ala Lys 
                165                 170                 175     


Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr Ser Ser 
            180                 185                 190         


Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu Leu Ser 
        195                 200                 205             


Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr His Ala 
    210                 215                 220                 


Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn Asn Arg 
225                 230                 235                 240 


Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg Cys Pro 
                245                 250                 255     


Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala Val Val 
            260                 265                 270         


Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu Lys Met 
        275                 280                 285             


Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Gln Pro Gly Lys Leu Thr 
    290                 295                 300                 


Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr Met Ala Ser Ser 
305                 310                 315                 320 


Cys Met Thr Arg Leu Ser Arg Ser Arg Thr Ala Ser Leu Thr Ser Ala 
                325                 330                 335     


Ala Ser Val Asp Gly Asn Arg Ser Arg Ser Arg Thr Leu Ser Gln Ser 
            340                 345                 350         


Ser Glu Ser Gly Thr Leu Ser Ser Gly Pro Pro Gly His Thr Met Glu 
        355                 360                 365             


Val Ser Cys 
    370     


<210>  3691
<211>  374
<212>  PRT
<213>  homo sapiens

<400>  3691

Met Leu Gln Asp Leu Ser Ala Ser Val Phe Phe Pro Pro Cys Ser Gln 
1               5                   10                  15      


His Arg Thr Leu Ala Gln Val Pro Asp Asn Asp Glu Gln Phe Val Pro 
            20                  25                  30          


Asp Tyr Gln Ala Glu Ser Leu Ala Phe His Gly Leu Pro Leu Lys Ile 
        35                  40                  45              


Lys Lys Glu Pro His Ser Pro Cys Ser Glu Ile Ser Ser Ala Cys Ser 
    50                  55                  60                  


Gln Glu Gln Pro Phe Lys Phe Ser Tyr Gly Glu Lys Cys Leu Tyr Asn 
65                  70                  75                  80  


Val Arg Phe Arg Arg Gln Leu Ser Glu Pro Cys Asn Ser Phe Pro Pro 
                85                  90                  95      


Leu Pro Thr Met Pro Arg Glu Gly Arg Pro Met Tyr Gln Arg Gln Met 
            100                 105                 110         


Ser Glu Pro Asn Ile Pro Phe Pro Pro Gln Gly Phe Lys Gln Glu Tyr 
        115                 120                 125             


His Asp Pro Val Tyr Glu His Asn Thr Met Val Gly Ser Ala Ala Ser 
    130                 135                 140                 


Gln Ser Phe Pro Pro Pro Leu Met Ile Lys Gln Glu Pro Arg Asp Phe 
145                 150                 155                 160 


Ala Tyr Asp Ser Glu Val Pro Ser Cys His Ser Ile Tyr Met Arg Gln 
                165                 170                 175     


Glu Gly Phe Leu Ala His Pro Ser Arg Thr Glu Gly Cys Met Phe Glu 
            180                 185                 190         


Lys Gly Pro Arg Gln Phe Tyr Asp Asp Thr Cys Val Val Pro Glu Lys 
        195                 200                 205             


Phe Asp Gly Asp Ile Lys Gln Glu Pro Gly Met Tyr Arg Glu Gly Pro 
    210                 215                 220                 


Thr Tyr Gln Arg Arg Gly Ser Leu Gln Leu Trp Gln Phe Leu Val Ala 
225                 230                 235                 240 


Leu Leu Asp Asp Pro Ser Asn Ser His Phe Ile Ala Trp Thr Gly Arg 
                245                 250                 255     


Gly Met Glu Phe Lys Leu Ile Glu Pro Glu Glu Val Ala Arg Arg Trp 
            260                 265                 270         


Gly Ile Gln Lys Asn Arg Pro Ala Met Asn Tyr Asp Lys Leu Ser Arg 
        275                 280                 285             


Ser Leu Arg Tyr Tyr Tyr Glu Lys Gly Ile Met Gln Lys Val Ala Gly 
    290                 295                 300                 


Glu Arg Tyr Val Tyr Lys Phe Val Cys Asp Pro Glu Ala Leu Phe Ser 
305                 310                 315                 320 


Met Ala Phe Pro Asp Asn Gln Arg Pro Leu Leu Lys Thr Asp Met Glu 
                325                 330                 335     


Arg His Ile Asn Glu Glu Asp Thr Val Pro Leu Ser His Phe Asp Glu 
            340                 345                 350         


Ser Met Ala Tyr Met Pro Glu Gly Gly Cys Cys Asn Pro His Pro Tyr 
        355                 360                 365             


Asn Glu Gly Tyr Val Tyr 
    370                 


<210>  3692
<211>  781
<212>  PRT
<213>  homo sapiens

<400>  3692

Met Ser Ser Glu Cys Asp Gly Gly Ser Lys Ala Val Met Asn Gly Leu 
1               5                   10                  15      


Ala Pro Gly Ser Asn Gly Gln Asp Lys Ala Thr Ala Asp Pro Leu Arg 
            20                  25                  30          


Ala Arg Ser Ile Ser Ala Val Lys Ile Ile Pro Val Lys Thr Val Lys 
        35                  40                  45              


Asn Ala Ser Gly Leu Val Leu Pro Thr Asp Met Asp Pro Thr Lys Ile 
    50                  55                  60                  


Cys Thr Gly Lys Gly Ala Val Thr Leu Arg Ala Ser Ser Ser Tyr Arg 
65                  70                  75                  80  


Glu Thr Pro Ser Ser Ser Pro Ala Ser Pro Gln Glu Thr Arg Gln His 
                85                  90                  95      


Glu Ser Lys Pro Gly Leu Glu Pro Glu Pro Ser Ser Ala Asp Glu Trp 
            100                 105                 110         


Arg Leu Ser Ser Ser Ala Asp Ala Asn Gly Asn Ala Gln Pro Ser Ser 
        115                 120                 125             


Leu Ala Ala Lys Gly Tyr Arg Ser Val His Pro Asn Leu Pro Ser Asp 
    130                 135                 140                 


Lys Ser Gln Asp Ser Ser Pro Leu Leu Asn Glu Val Ser Ser Ser Leu 
145                 150                 155                 160 


Ile Gly Thr Asp Ser Gln Ala Phe Pro Ser Val Ser Lys Pro Ser Ser 
                165                 170                 175     


Ala Tyr Pro Ser Thr Thr Ile Val Asn Pro Thr Ile Val Leu Leu Gln 
            180                 185                 190         


His Asn Arg Glu Gln Gln Lys Arg Leu Ser Ser Leu Ser Asp Pro Val 
        195                 200                 205             


Ser Glu Arg Arg Val Gly Glu Gln Asp Ser Ala Pro Thr Gln Glu Lys 
    210                 215                 220                 


Pro Thr Ser Pro Gly Lys Ala Ile Glu Lys Arg Ala Lys Asp Asp Ser 
225                 230                 235                 240 


Arg Arg Val Val Lys Ser Thr Gln Asp Leu Ser Asp Val Ser Met Asp 
                245                 250                 255     


Glu Val Gly Ile Pro Leu Arg Asn Thr Glu Arg Ser Lys Asp Trp Tyr 
            260                 265                 270         


Lys Thr Met Phe Lys Gln Ile His Lys Leu Asn Arg Asp Asp Asp Ser 
        275                 280                 285             


Asp Leu Tyr Ser Pro Arg Tyr Ser Phe Ser Glu Asp Thr Lys Ser Pro 
    290                 295                 300                 


Leu Ser Val Pro Arg Ser Lys Ser Glu Met Ser Tyr Ile Asp Gly Glu 
305                 310                 315                 320 


Lys Val Val Lys Arg Ser Ala Thr Leu Pro Leu Pro Ala Arg Ser Ser 
                325                 330                 335     


Ser Leu Lys Ser Ser Ser Glu Arg Asn Asp Trp Glu Pro Pro Asp Lys 
            340                 345                 350         


Lys Val Asp Thr Arg Lys Tyr Arg Ala Glu Pro Lys Ser Ile Tyr Glu 
        355                 360                 365             


Tyr Gln Pro Gly Lys Ser Ser Val Leu Thr Asn Glu Lys Met Ser Ser 
    370                 375                 380                 


Ala Ile Ser Pro Thr Pro Glu Ile Ser Ser Glu Thr Pro Gly Tyr Ile 
385                 390                 395                 400 


Tyr Ser Ser Asn Phe His Ala Val Lys Arg Glu Ser Asp Gly Ala Pro 
                405                 410                 415     


Gly Asp Leu Thr Ser Leu Glu Asn Glu Arg Gln Ile Tyr Lys Ser Val 
            420                 425                 430         


Leu Glu Gly Gly Asp Ile Pro Leu Gln Gly Leu Ser Gly Leu Lys Arg 
        435                 440                 445             


Pro Ser Ser Ser Ala Ser Thr Lys Asp Ser Glu Ser Pro Arg His Phe 
    450                 455                 460                 


Ile Pro Ala Asp Tyr Leu Glu Ser Thr Glu Glu Phe Ile Arg Arg Arg 
465                 470                 475                 480 


His Asp Asp Lys Glu Lys Leu Leu Ala Asp Gln Arg Arg Leu Lys Arg 
                485                 490                 495     


Glu Gln Glu Glu Ala Asp Ile Ala Ala Arg Arg His Thr Gly Val Ile 
            500                 505                 510         


Pro Thr His His Gln Phe Ile Thr Asn Glu Arg Phe Gly Asp Leu Leu 
        515                 520                 525             


Asn Ile Asp Asp Thr Ala Lys Arg Lys Ser Gly Ser Glu Met Arg Pro 
    530                 535                 540                 


Ala Arg Ala Lys Phe Asp Phe Lys Ala Gln Thr Leu Lys Glu Leu Pro 
545                 550                 555                 560 


Leu Gln Lys Gly Asp Ile Val Tyr Ile Tyr Lys Gln Ile Asp Gln Asn 
                565                 570                 575     


Trp Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe Pro Arg Thr 
            580                 585                 590         


Tyr Ile Glu Leu Leu Pro Pro Ala Glu Lys Ala Gln Pro Lys Lys Leu 
        595                 600                 605             


Thr Pro Val Gln Val Leu Glu Tyr Gly Glu Ala Ile Ala Lys Phe Asn 
    610                 615                 620                 


Phe Asn Gly Asp Thr Gln Val Glu Met Ser Phe Arg Lys Gly Glu Arg 
625                 630                 635                 640 


Ile Thr Leu Leu Arg Gln Val Asp Glu Asn Trp Tyr Glu Gly Arg Ile 
                645                 650                 655     


Pro Gly Thr Ser Arg Gln Gly Ile Phe Pro Ile Thr Tyr Val Asp Val 
            660                 665                 670         


Ile Lys Arg Pro Leu Val Lys Asn Pro Val Asp Tyr Met Asp Leu Pro 
        675                 680                 685             


Phe Ser Ser Ser Pro Ser Arg Ser Ala Thr Ala Ser Pro Gln Gln Pro 
    690                 695                 700                 


Gln Ala Gln Gln Arg Arg Val Thr Pro Asp Arg Ser Gln Thr Ser Gln 
705                 710                 715                 720 


Asp Leu Phe Ser Tyr Gln Ala Leu Tyr Ser Tyr Ile Pro Gln Asn Asp 
                725                 730                 735     


Asp Glu Leu Glu Leu Arg Asp Gly Asp Ile Val Asp Val Met Glu Lys 
            740                 745                 750         


Cys Asp Asp Gly Trp Phe Val Gly Thr Ser Arg Arg Thr Lys Gln Phe 
        755                 760                 765             


Gly Thr Phe Pro Gly Asn Tyr Val Lys Pro Leu Tyr Leu 
    770                 775                 780     


<210>  3693
<211>  345
<212>  PRT
<213>  homo sapiens

<400>  3693

Met Val Ala Ala Leu Leu Gly Gly Gly Gly Glu Ala Arg Gly Gly Thr 
1               5                   10                  15      


Val Pro Gly Ala Trp Leu Cys Leu Met Ala Leu Leu Gln Leu Leu Gly 
            20                  25                  30          


Ser Ala Pro Arg Gly Ser Gly Leu Ala His Gly Arg Arg Leu Ile Cys 
        35                  40                  45              


Trp Gln Ala Leu Leu Gln Cys Gln Gly Glu Pro Glu Cys Ser Tyr Ala 
    50                  55                  60                  


Tyr Asn Gln Tyr Ala Glu Ala Cys Ala Pro Val Leu Ala Gln His Gly 
65                  70                  75                  80  


Gly Gly Asp Ala Pro Gly Ala Ala Ala Ala Ala Phe Pro Ala Ser Ala 
                85                  90                  95      


Ala Ser Phe Ser Ser Arg Trp Arg Cys Pro Ser His Cys Ile Ser Ala 
            100                 105                 110         


Leu Ile Gln Leu Asn His Thr Arg Arg Gly Pro Ala Leu Glu Asp Cys 
        115                 120                 125             


Asp Cys Ala Gln Asp Glu Asn Cys Lys Ser Thr Lys Arg Ala Ile Glu 
    130                 135                 140                 


Pro Cys Leu Pro Arg Thr Ser Gly Gly Gly Ala Gly Gly Pro Gly Ala 
145                 150                 155                 160 


Gly Gly Val Met Gly Cys Thr Glu Ala Arg Arg Arg Cys Asp Arg Asp 
                165                 170                 175     


Ser Arg Cys Asn Leu Ala Leu Ser Arg Tyr Leu Thr Tyr Cys Gly Lys 
            180                 185                 190         


Val Phe Asn Gly Leu Arg Cys Thr Asp Glu Cys Arg Thr Val Ile Glu 
        195                 200                 205             


Asp Met Leu Ala Met Pro Lys Ala Ala Leu Leu Asn Asp Cys Val Cys 
    210                 215                 220                 


Asp Gly Leu Glu Arg Pro Ile Cys Glu Ser Val Lys Glu Asn Met Ala 
225                 230                 235                 240 


Arg Leu Cys Phe Gly Ala Glu Leu Gly Asn Gly Pro Gly Ser Ser Gly 
                245                 250                 255     


Ser Asp Gly Gly Leu Asp Asp Tyr Tyr Asp Glu Asp Tyr Asp Asp Glu 
            260                 265                 270         


Gln Arg Thr Gly Gly Ala Gly Gly Glu Gln Pro Leu Asp Asp Asp Asp 
        275                 280                 285             


Gly Val Pro His Pro Pro Arg Pro Gly Ser Gly Ala Ala Ala Ser Gly 
    290                 295                 300                 


Gly Arg Gly Asp Leu Pro Tyr Gly Pro Gly Arg Arg Ser Ser Gly Gly 
305                 310                 315                 320 


Gly Gly Arg Leu Ala Pro Arg Gly Ala Trp Thr Pro Leu Ala Ser Ile 
                325                 330                 335     


Leu Leu Leu Leu Leu Gly Pro Leu Phe 
            340                 345 


<210>  3694
<211>  238
<212>  PRT
<213>  homo sapiens

<400>  3694

Met Leu Cys Cys Met Arg Arg Thr Lys Gln Val Glu Lys Asn Asp Asp 
1               5                   10                  15      


Asp Gln Lys Ile Glu Gln Asp Gly Ile Lys Pro Glu Asp Lys Ala His 
            20                  25                  30          


Lys Ala Ala Thr Lys Ile Gln Ala Ser Phe Arg Gly His Ile Thr Arg 
        35                  40                  45              


Lys Lys Leu Lys Gly Glu Lys Lys Asp Asp Val Gln Ala Ala Glu Ala 
    50                  55                  60                  


Glu Ala Asn Lys Lys Asp Glu Ala Pro Val Ala Asp Gly Val Glu Lys 
65                  70                  75                  80  


Lys Gly Glu Gly Thr Thr Thr Ala Glu Ala Ala Pro Ala Thr Gly Ser 
                85                  90                  95      


Lys Pro Asp Glu Pro Gly Lys Ala Gly Glu Thr Pro Ser Glu Glu Lys 
            100                 105                 110         


Lys Gly Glu Gly Asp Ala Ala Thr Glu Gln Ala Ala Pro Gln Ala Pro 
        115                 120                 125             


Ala Ser Ser Glu Glu Lys Ala Gly Ser Ala Glu Thr Glu Ser Ala Thr 
    130                 135                 140                 


Lys Ala Ser Thr Asp Asn Ser Pro Ser Ser Lys Ala Glu Asp Ala Pro 
145                 150                 155                 160 


Ala Lys Glu Glu Pro Lys Gln Ala Asp Val Pro Ala Ala Val Thr Ala 
                165                 170                 175     


Ala Ala Ala Thr Thr Pro Ala Ala Glu Asp Ala Ala Ala Lys Ala Thr 
            180                 185                 190         


Ala Gln Pro Pro Thr Glu Thr Gly Glu Ser Ser Gln Ala Glu Glu Asn 
        195                 200                 205             


Ile Glu Ala Val Asp Glu Thr Lys Pro Lys Glu Ser Ala Arg Gln Asp 
    210                 215                 220                 


Glu Gly Lys Glu Glu Glu Pro Glu Ala Asp Gln Glu His Ala 
225                 230                 235             


<210>  3695
<211>  1174
<212>  PRT
<213>  homo sapiens

<400>  3695

Met Ala Arg Gln Pro Pro Pro Pro Trp Val His Ala Ala Phe Leu Leu 
1               5                   10                  15      


Cys Leu Leu Ser Leu Gly Gly Ala Ile Glu Ile Pro Met Asp Leu Thr 
            20                  25                  30          


Gln Pro Pro Thr Ile Thr Lys Gln Ser Ala Lys Asp His Ile Val Asp 
        35                  40                  45              


Pro Arg Asp Asn Ile Leu Ile Glu Cys Glu Ala Lys Gly Asn Pro Ala 
    50                  55                  60                  


Pro Ser Phe His Trp Thr Arg Asn Ser Arg Phe Phe Asn Ile Ala Lys 
65                  70                  75                  80  


Asp Pro Arg Val Ser Met Arg Arg Arg Ser Gly Thr Leu Val Ile Asp 
                85                  90                  95      


Phe Arg Ser Gly Gly Arg Pro Glu Glu Tyr Glu Gly Glu Tyr Gln Cys 
            100                 105                 110         


Phe Ala Arg Asn Lys Phe Gly Thr Ala Leu Ser Asn Arg Ile Arg Leu 
        115                 120                 125             


Gln Val Ser Lys Ser Pro Leu Trp Pro Lys Glu Asn Leu Asp Pro Val 
    130                 135                 140                 


Val Val Gln Glu Gly Ala Pro Leu Thr Leu Gln Cys Asn Pro Pro Pro 
145                 150                 155                 160 


Gly Leu Pro Ser Pro Val Ile Phe Trp Met Ser Ser Ser Met Glu Pro 
                165                 170                 175     


Ile Thr Gln Asp Lys Arg Val Ser Gln Gly His Asn Gly Asp Leu Tyr 
            180                 185                 190         


Phe Ser Asn Val Met Leu Gln Asp Met Gln Thr Asp Tyr Ser Cys Asn 
        195                 200                 205             


Ala Arg Phe His Phe Thr His Thr Ile Gln Gln Lys Asn Pro Phe Thr 
    210                 215                 220                 


Leu Lys Val Leu Thr Asn His Pro Tyr Asn Asp Ser Ser Leu Arg Asn 
225                 230                 235                 240 


His Pro Asp Met Tyr Ser Ala Arg Gly Val Ala Glu Arg Thr Pro Ser 
                245                 250                 255     


Phe Met Tyr Pro Gln Gly Thr Ala Ser Ser Gln Met Val Leu Arg Gly 
            260                 265                 270         


Met Asp Leu Leu Leu Glu Cys Ile Ala Ser Gly Val Pro Thr Pro Asp 
        275                 280                 285             


Ile Ala Trp Tyr Lys Lys Gly Gly Asp Leu Pro Ser Asp Lys Ala Lys 
    290                 295                 300                 


Phe Glu Asn Phe Asn Lys Ala Leu Arg Ile Thr Asn Val Ser Glu Glu 
305                 310                 315                 320 


Asp Ser Gly Glu Tyr Phe Cys Leu Ala Ser Asn Lys Met Gly Ser Ile 
                325                 330                 335     


Arg His Thr Ile Ser Val Arg Val Lys Ala Ala Pro Tyr Trp Leu Asp 
            340                 345                 350         


Glu Pro Lys Asn Leu Ile Leu Ala Pro Gly Glu Asp Gly Arg Leu Val 
        355                 360                 365             


Cys Arg Ala Asn Gly Asn Pro Lys Pro Thr Val Gln Trp Met Val Asn 
    370                 375                 380                 


Gly Glu Pro Leu Gln Ser Ala Pro Pro Asn Pro Asn Arg Glu Val Ala 
385                 390                 395                 400 


Gly Asp Thr Ile Ile Phe Arg Asp Thr Gln Ile Ser Ser Arg Ala Val 
                405                 410                 415     


Tyr Gln Cys Asn Thr Ser Asn Glu His Gly Tyr Leu Leu Ala Asn Ala 
            420                 425                 430         


Phe Val Ser Val Leu Asp Val Pro Pro Arg Met Leu Ser Pro Arg Asn 
        435                 440                 445             


Gln Leu Ile Arg Val Ile Leu Tyr Asn Arg Thr Arg Leu Asp Cys Pro 
    450                 455                 460                 


Phe Phe Gly Ser Pro Ile Pro Thr Leu Arg Trp Phe Lys Asn Gly Gln 
465                 470                 475                 480 


Gly Ser Asn Leu Asp Gly Gly Asn Tyr His Val Tyr Glu Asn Gly Ser 
                485                 490                 495     


Leu Glu Ile Lys Met Ile Arg Lys Glu Asp Gln Gly Ile Tyr Thr Cys 
            500                 505                 510         


Val Ala Thr Asn Ile Leu Gly Lys Ala Glu Asn Gln Val Arg Leu Glu 
        515                 520                 525             


Val Lys Asp Pro Thr Arg Ile Tyr Arg Met Pro Glu Asp Gln Val Ala 
    530                 535                 540                 


Arg Arg Gly Thr Thr Val Gln Leu Glu Cys Arg Val Lys His Asp Pro 
545                 550                 555                 560 


Ser Leu Lys Leu Thr Val Ser Trp Leu Lys Asp Asp Glu Pro Leu Tyr 
                565                 570                 575     


Ile Gly Asn Arg Met Lys Lys Glu Asp Asp Ser Leu Thr Ile Phe Gly 
            580                 585                 590         


Val Ala Glu Arg Asp Gln Gly Ser Tyr Thr Cys Val Ala Ser Thr Glu 
        595                 600                 605             


Leu Asp Gln Asp Leu Ala Lys Ala Tyr Leu Thr Val Leu Gly Arg Pro 
    610                 615                 620                 


Asp Arg Pro Arg Asp Leu Glu Leu Thr Asp Leu Ala Glu Arg Ser Val 
625                 630                 635                 640 


Arg Leu Thr Trp Ile Pro Gly Asp Ala Asn Asn Ser Pro Ile Thr Asp 
                645                 650                 655     


Tyr Val Val Gln Phe Glu Glu Asp Gln Phe Gln Pro Gly Val Trp His 
            660                 665                 670         


Asp His Ser Lys Tyr Pro Gly Ser Val Asn Ser Ala Val Leu Arg Leu 
        675                 680                 685             


Ser Pro Tyr Val Asn Tyr Gln Phe Arg Val Ile Ala Ile Asn Glu Val 
    690                 695                 700                 


Gly Ser Ser His Pro Ser Leu Pro Ser Glu Arg Tyr Arg Thr Ser Gly 
705                 710                 715                 720 


Ala Pro Pro Glu Ser Asn Pro Gly Asp Val Lys Gly Glu Gly Thr Arg 
                725                 730                 735     


Lys Asn Asn Met Glu Ile Thr Trp Thr Pro Met Asn Ala Thr Ser Ala 
            740                 745                 750         


Phe Gly Pro Asn Leu Arg Tyr Ile Val Lys Trp Arg Arg Arg Glu Thr 
        755                 760                 765             


Arg Glu Ala Trp Asn Asn Val Thr Val Trp Gly Ser Arg Tyr Val Val 
    770                 775                 780                 


Gly Gln Thr Pro Val Tyr Val Pro Tyr Glu Ile Arg Val Gln Ala Glu 
785                 790                 795                 800 


Asn Asp Phe Gly Lys Gly Pro Glu Pro Glu Ser Val Ile Gly Tyr Ser 
                805                 810                 815     


Gly Glu Asp Tyr Pro Arg Ala Ala Pro Thr Glu Val Lys Val Arg Val 
            820                 825                 830         


Met Asn Ser Thr Ala Ile Ser Leu Gln Trp Asn Arg Val Tyr Ser Asp 
        835                 840                 845             


Thr Val Gln Gly Gln Leu Arg Glu Tyr Arg Ala Tyr Tyr Trp Arg Glu 
    850                 855                 860                 


Ser Ser Leu Leu Lys Asn Leu Trp Val Ser Gln Lys Arg Gln Gln Ala 
865                 870                 875                 880 


Ser Phe Pro Gly Asp Arg Leu Arg Gly Val Val Ser Arg Leu Phe Pro 
                885                 890                 895     


Tyr Ser Asn Tyr Lys Leu Glu Met Val Val Val Asn Gly Arg Gly Asp 
            900                 905                 910         


Gly Pro Arg Ser Glu Thr Lys Glu Phe Thr Thr Pro Glu Gly Val Pro 
        915                 920                 925             


Ser Ala Pro Arg Arg Phe Arg Val Arg Gln Pro Asn Leu Glu Thr Ile 
    930                 935                 940                 


Asn Leu Glu Trp Asp His Pro Glu His Pro Asn Gly Ile Met Ile Gly 
945                 950                 955                 960 


Tyr Thr Leu Lys Tyr Val Ala Phe Asn Gly Thr Lys Val Gly Lys Gln 
                965                 970                 975     


Ile Val Glu Asn Phe Ser Pro Asn Gln Thr Lys Phe Thr Val Gln Arg 
            980                 985                 990         


Thr Asp Pro Val Ser Arg Tyr Arg  Phe Thr Leu Ser Ala  Arg Thr Gln 
        995                 1000                 1005             


Val Gly  Ser Gly Glu Ala Val  Thr Glu Glu Ser Pro  Ala Pro Pro 
    1010                 1015                 1020             


Asn Glu  Ala Thr Pro Thr Ala  Ala Tyr Thr Asn Asn  Gln Ala Asp 
    1025                 1030                 1035             


Ile Ala  Thr Gln Gly Trp Phe  Ile Gly Leu Met Cys  Ala Ile Ala 
    1040                 1045                 1050             


Leu Leu  Val Leu Ile Leu Leu  Ile Val Cys Phe Ile  Lys Arg Ser 
    1055                 1060                 1065             


Arg Gly  Gly Lys Tyr Pro Val  Arg Glu Lys Lys Asp  Val Pro Leu 
    1070                 1075                 1080             


Gly Pro  Glu Asp Pro Lys Glu  Glu Asp Gly Ser Phe  Asp Tyr Ser 
    1085                 1090                 1095             


Asp Glu  Asp Asn Lys Pro Leu  Gln Gly Ser Gln Thr  Ser Leu Asp 
    1100                 1105                 1110             


Gly Thr  Ile Lys Gln Gln Glu  Ser Asp Asp Ser Leu  Val Asp Tyr 
    1115                 1120                 1125             


Gly Glu  Gly Gly Glu Gly Gln  Phe Asn Glu Asp Gly  Ser Phe Ile 
    1130                 1135                 1140             


Gly Gln  Tyr Thr Val Lys Lys  Asp Lys Glu Glu Thr  Glu Gly Asn 
    1145                 1150                 1155             


Glu Ser  Ser Glu Ala Thr Ser  Pro Val Asn Ala Ile  Tyr Ser Leu 
    1160                 1165                 1170             


Ala 
    


<210>  3696
<211>  556
<212>  PRT
<213>  homo sapiens

<400>  3696

Met Met Asn Lys Leu Tyr Ile Gly Asn Leu Ser Pro Ala Val Thr Ala 
1               5                   10                  15      


Asp Asp Leu Arg Gln Leu Phe Gly Asp Arg Lys Leu Pro Leu Ala Gly 
            20                  25                  30          


Gln Val Leu Leu Lys Ser Gly Tyr Ala Phe Val Asp Tyr Pro Asp Gln 
        35                  40                  45              


Asn Trp Ala Ile Arg Ala Ile Glu Thr Leu Ser Gly Lys Val Glu Leu 
    50                  55                  60                  


His Gly Lys Ile Met Glu Val Asp Tyr Ser Val Ser Lys Lys Leu Arg 
65                  70                  75                  80  


Ser Arg Lys Ile Gln Ile Arg Asn Ile Pro Pro His Leu Gln Trp Glu 
                85                  90                  95      


Val Leu Asp Gly Leu Leu Ala Gln Tyr Gly Thr Val Glu Asn Val Glu 
            100                 105                 110         


Gln Val Asn Thr Asp Thr Glu Thr Ala Val Val Asn Val Thr Tyr Ala 
        115                 120                 125             


Thr Arg Glu Glu Ala Lys Ile Ala Met Glu Lys Leu Ser Gly His Gln 
    130                 135                 140                 


Phe Glu Asn Tyr Ser Phe Lys Ile Ser Tyr Ile Pro Asp Glu Glu Val 
145                 150                 155                 160 


Ser Ser Pro Ser Pro Pro Gln Arg Ala Gln Arg Gly Asp His Ser Ser 
                165                 170                 175     


Arg Glu Gln Gly His Ala Pro Gly Gly Thr Ser Gln Ala Arg Gln Ile 
            180                 185                 190         


Asp Phe Pro Leu Arg Ile Leu Val Pro Thr Gln Phe Val Gly Ala Ile 
        195                 200                 205             


Ile Gly Lys Glu Gly Leu Thr Ile Lys Asn Ile Thr Lys Gln Thr Gln 
    210                 215                 220                 


Ser Arg Val Asp Ile His Arg Lys Glu Asn Ser Gly Ala Ala Glu Lys 
225                 230                 235                 240 


Pro Val Thr Ile His Ala Thr Pro Glu Gly Thr Ser Glu Ala Cys Arg 
                245                 250                 255     


Met Ile Leu Glu Ile Met Gln Lys Glu Ala Asp Glu Thr Lys Leu Ala 
            260                 265                 270         


Glu Glu Ile Pro Leu Lys Ile Leu Ala His Asn Gly Leu Val Gly Arg 
        275                 280                 285             


Leu Ile Gly Lys Glu Gly Arg Asn Leu Lys Lys Ile Glu His Glu Thr 
    290                 295                 300                 


Gly Thr Lys Ile Thr Ile Ser Ser Leu Gln Asp Leu Ser Ile Tyr Asn 
305                 310                 315                 320 


Pro Glu Arg Thr Ile Thr Val Lys Gly Thr Val Glu Ala Cys Ala Ser 
                325                 330                 335     


Ala Glu Ile Glu Ile Met Lys Lys Leu Arg Glu Ala Phe Glu Asn Asp 
            340                 345                 350         


Met Leu Ala Val Asn Thr His Ser Gly Tyr Phe Ser Ser Leu Tyr Pro 
        355                 360                 365             


His His Gln Phe Gly Pro Phe Pro His His His Ser Tyr Pro Glu Gln 
    370                 375                 380                 


Glu Ile Val Asn Leu Phe Ile Pro Thr Gln Ala Val Gly Ala Ile Ile 
385                 390                 395                 400 


Gly Lys Lys Gly Ala His Ile Lys Gln Leu Ala Arg Phe Ala Gly Ala 
                405                 410                 415     


Ser Ile Lys Ile Ala Pro Ala Glu Gly Pro Asp Val Ser Glu Arg Met 
            420                 425                 430         


Val Ile Ile Thr Gly Pro Pro Glu Ala Gln Phe Lys Ala Gln Gly Arg 
        435                 440                 445             


Ile Phe Gly Lys Leu Lys Glu Glu Asn Phe Phe Asn Pro Lys Glu Glu 
    450                 455                 460                 


Val Lys Leu Glu Ala His Ile Arg Val Pro Ser Ser Thr Ala Gly Arg 
465                 470                 475                 480 


Val Ile Gly Lys Gly Gly Lys Thr Val Asn Glu Leu Gln Asn Leu Thr 
                485                 490                 495     


Ser Ala Glu Val Ile Val Pro Arg Asp Gln Thr Pro Asp Glu Asn Glu 
            500                 505                 510         


Glu Val Ile Val Arg Ile Ile Gly His Phe Phe Ala Ser Gln Thr Ala 
        515                 520                 525             


Gln Arg Lys Ile Arg Glu Ile Val Gln Gln Val Lys Gln Gln Glu Gln 
    530                 535                 540                 


Lys Tyr Pro Gln Gly Val Ala Ser Gln Arg Ser Lys 
545                 550                 555     


<210>  3697
<211>  599
<212>  PRT
<213>  homo sapiens

<400>  3697

Met Met Asn Lys Leu Tyr Ile Gly Asn Leu Ser Pro Ala Val Thr Ala 
1               5                   10                  15      


Asp Asp Leu Arg Gln Leu Phe Gly Asp Arg Lys Leu Pro Leu Ala Gly 
            20                  25                  30          


Gln Val Leu Leu Lys Ser Gly Tyr Ala Phe Val Asp Tyr Pro Asp Gln 
        35                  40                  45              


Asn Trp Ala Ile Arg Ala Ile Glu Thr Leu Ser Gly Lys Val Glu Leu 
    50                  55                  60                  


His Gly Lys Ile Met Glu Val Asp Tyr Ser Val Ser Lys Lys Leu Arg 
65                  70                  75                  80  


Ser Arg Lys Ile Gln Ile Arg Asn Ile Pro Pro His Leu Gln Trp Glu 
                85                  90                  95      


Val Leu Asp Gly Leu Leu Ala Gln Tyr Gly Thr Val Glu Asn Val Glu 
            100                 105                 110         


Gln Val Asn Thr Asp Thr Glu Thr Ala Val Val Asn Val Thr Tyr Ala 
        115                 120                 125             


Thr Arg Glu Glu Ala Lys Ile Ala Met Glu Lys Leu Ser Gly His Gln 
    130                 135                 140                 


Phe Glu Asn Tyr Ser Phe Lys Ile Ser Tyr Ile Pro Asp Glu Glu Val 
145                 150                 155                 160 


Ser Ser Pro Ser Pro Pro Gln Arg Ala Gln Arg Gly Asp His Ser Ser 
                165                 170                 175     


Arg Glu Gln Gly His Ala Pro Gly Gly Thr Ser Gln Ala Arg Gln Ile 
            180                 185                 190         


Asp Phe Pro Leu Arg Ile Leu Val Pro Thr Gln Phe Val Gly Ala Ile 
        195                 200                 205             


Ile Gly Lys Glu Gly Leu Thr Ile Lys Asn Ile Thr Lys Gln Thr Gln 
    210                 215                 220                 


Ser Arg Val Asp Ile His Arg Lys Glu Asn Ser Gly Ala Ala Glu Lys 
225                 230                 235                 240 


Pro Val Thr Ile His Ala Thr Pro Glu Gly Thr Ser Glu Ala Cys Arg 
                245                 250                 255     


Met Ile Leu Glu Ile Met Gln Lys Glu Ala Asp Glu Thr Lys Leu Ala 
            260                 265                 270         


Glu Glu Ile Pro Leu Lys Ile Leu Ala His Asn Gly Leu Val Gly Arg 
        275                 280                 285             


Leu Ile Gly Lys Glu Gly Arg Asn Leu Lys Lys Ile Glu His Glu Thr 
    290                 295                 300                 


Gly Thr Lys Ile Thr Ile Ser Ser Leu Gln Asp Leu Ser Ile Tyr Asn 
305                 310                 315                 320 


Pro Glu Arg Thr Ile Thr Val Lys Gly Thr Val Glu Ala Cys Ala Ser 
                325                 330                 335     


Ala Glu Ile Glu Ile Met Lys Lys Leu Arg Glu Ala Phe Glu Asn Asp 
            340                 345                 350         


Met Leu Ala Val Asn Gln Gln Ala Asn Leu Ile Pro Gly Leu Asn Leu 
        355                 360                 365             


Ser Ala Leu Gly Ile Phe Ser Thr Gly Leu Ser Val Leu Ser Pro Pro 
    370                 375                 380                 


Ala Gly Pro Arg Gly Ala Pro Pro Ala Ala Pro Tyr His Pro Phe Thr 
385                 390                 395                 400 


Thr His Ser Gly Tyr Phe Ser Ser Leu Tyr Pro His His Gln Phe Gly 
                405                 410                 415     


Pro Phe Pro His His His Ser Tyr Pro Glu Gln Glu Ile Val Asn Leu 
            420                 425                 430         


Phe Ile Pro Thr Gln Ala Val Gly Ala Ile Ile Gly Lys Lys Gly Ala 
        435                 440                 445             


His Ile Lys Gln Leu Ala Arg Phe Ala Gly Ala Ser Ile Lys Ile Ala 
    450                 455                 460                 


Pro Ala Glu Gly Pro Asp Val Ser Glu Arg Met Val Ile Ile Thr Gly 
465                 470                 475                 480 


Pro Pro Glu Ala Gln Phe Lys Ala Gln Gly Arg Ile Phe Gly Lys Leu 
                485                 490                 495     


Lys Glu Glu Asn Phe Phe Asn Pro Lys Glu Glu Val Lys Leu Glu Ala 
            500                 505                 510         


His Ile Arg Val Pro Ser Ser Thr Ala Gly Arg Val Ile Gly Lys Gly 
        515                 520                 525             


Gly Lys Thr Val Asn Glu Leu Gln Asn Leu Thr Ser Ala Glu Val Ile 
    530                 535                 540                 


Val Pro Arg Asp Gln Thr Pro Asp Glu Asn Glu Glu Val Ile Val Arg 
545                 550                 555                 560 


Ile Ile Gly His Phe Phe Ala Ser Gln Thr Ala Gln Arg Lys Ile Arg 
                565                 570                 575     


Glu Ile Val Gln Gln Val Lys Gln Gln Glu Gln Lys Tyr Pro Gln Gly 
            580                 585                 590         


Val Ala Ser Gln Arg Ser Lys 
        595                 


<210>  3698
<211>  626
<212>  PRT
<213>  homo sapiens

<400>  3698

Met Ala Ala Arg Pro Ala Ala Thr Leu Ala Trp Ser Leu Leu Leu Leu 
1               5                   10                  15      


Ser Ser Ala Leu Leu Arg Glu Gly Cys Arg Ala Arg Phe Val Ala Glu 
            20                  25                  30          


Arg Asp Ser Glu Asp Asp Gly Glu Glu Pro Val Val Phe Pro Glu Ser 
        35                  40                  45              


Pro Leu Gln Ser Pro Thr Val Leu Val Ala Val Leu Ala Arg Asn Ala 
    50                  55                  60                  


Ala His Thr Leu Pro His Phe Leu Gly Cys Leu Glu Arg Leu Asp Tyr 
65                  70                  75                  80  


Pro Lys Ser Arg Met Ala Ile Trp Ala Ala Thr Asp His Asn Val Asp 
                85                  90                  95      


Asn Thr Thr Glu Ile Phe Arg Glu Trp Leu Lys Asn Val Gln Arg Leu 
            100                 105                 110         


Tyr His Tyr Val Glu Trp Arg Pro Met Asp Glu Pro Glu Ser Tyr Pro 
        115                 120                 125             


Asp Glu Ile Gly Pro Lys His Trp Pro Thr Ser Arg Phe Ala His Val 
    130                 135                 140                 


Met Lys Leu Arg Gln Ala Ala Leu Arg Thr Ala Arg Glu Lys Trp Ser 
145                 150                 155                 160 


Asp Tyr Ile Leu Phe Ile Asp Val Asp Asn Phe Leu Thr Asn Pro Gln 
                165                 170                 175     


Thr Leu Asn Leu Leu Ile Ala Glu Asn Lys Thr Ile Val Ala Pro Met 
            180                 185                 190         


Leu Glu Ser Arg Gly Leu Tyr Ser Asn Phe Trp Cys Gly Ile Thr Pro 
        195                 200                 205             


Lys Gly Phe Tyr Lys Arg Thr Pro Asp Tyr Val Gln Ile Arg Glu Trp 
    210                 215                 220                 


Lys Arg Thr Gly Cys Phe Pro Val Pro Met Val His Ser Thr Phe Leu 
225                 230                 235                 240 


Ile Asp Leu Arg Lys Glu Ala Ser Asp Lys Leu Thr Phe Tyr Pro Pro 
                245                 250                 255     


His Gln Asp Tyr Thr Trp Thr Phe Asp Asp Ile Ile Val Phe Ala Phe 
            260                 265                 270         


Ser Ser Arg Gln Ala Gly Ile Gln Met Tyr Leu Cys Asn Arg Glu His 
        275                 280                 285             


Tyr Gly Tyr Leu Pro Ile Pro Leu Lys Pro His Gln Thr Leu Gln Glu 
    290                 295                 300                 


Asp Ile Glu Asn Leu Ile His Val Gln Ile Glu Ala Met Ile Asp Arg 
305                 310                 315                 320 


Pro Pro Met Glu Pro Ser Gln Tyr Val Ser Val Val Pro Lys Tyr Pro 
                325                 330                 335     


Asp Lys Met Gly Phe Asp Glu Ile Phe Met Ile Asn Leu Lys Arg Arg 
            340                 345                 350         


Lys Asp Arg Arg Asp Arg Met Leu Arg Thr Leu Tyr Glu Gln Glu Ile 
        355                 360                 365             


Glu Val Lys Ile Val Glu Ala Val Asp Gly Lys Ala Leu Asn Thr Ser 
    370                 375                 380                 


Gln Leu Lys Ala Leu Asn Ile Glu Met Leu Pro Gly Tyr Arg Asp Pro 
385                 390                 395                 400 


Tyr Ser Ser Arg Pro Leu Thr Arg Gly Glu Ile Gly Cys Phe Leu Ser 
                405                 410                 415     


His Tyr Ser Val Trp Lys Glu Val Ile Asp Arg Glu Leu Glu Lys Thr 
            420                 425                 430         


Leu Val Ile Glu Asp Asp Val Arg Phe Glu His Gln Phe Lys Lys Lys 
        435                 440                 445             


Leu Met Lys Leu Met Asp Asn Ile Asp Gln Ala Gln Leu Asp Trp Glu 
    450                 455                 460                 


Leu Ile Tyr Ile Gly Arg Lys Arg Met Gln Val Lys Glu Pro Glu Lys 
465                 470                 475                 480 


Ala Val Pro Asn Val Ala Asn Leu Val Glu Ala Asp Tyr Ser Tyr Trp 
                485                 490                 495     


Thr Leu Gly Tyr Val Ile Ser Leu Glu Gly Ala Gln Lys Leu Val Gly 
            500                 505                 510         


Ala Asn Pro Phe Gly Lys Met Leu Pro Val Asp Glu Phe Leu Pro Val 
        515                 520                 525             


Met Tyr Asn Lys His Pro Val Ala Glu Tyr Lys Glu Tyr Tyr Glu Ser 
    530                 535                 540                 


Arg Asp Leu Lys Ala Phe Ser Ala Glu Pro Leu Leu Ile Tyr Pro Thr 
545                 550                 555                 560 


His Tyr Thr Gly Gln Pro Gly Tyr Leu Ser Asp Thr Glu Thr Ser Thr 
                565                 570                 575     


Ile Trp Asp Asn Glu Thr Val Ala Thr Asp Trp Asp Arg Thr His Ala 
            580                 585                 590         


Trp Lys Ser Arg Lys Gln Ser Arg Ile Tyr Ser Asn Ala Lys Asn Thr 
        595                 600                 605             


Glu Ala Leu Pro Pro Pro Thr Ser Leu Asp Thr Val Pro Ser Arg Asp 
    610                 615                 620                 


Glu Leu 
625     


<210>  3699
<211>  372
<212>  PRT
<213>  homo sapiens

<400>  3699

Met Glu Leu Glu Gly Gln Trp Trp Arg Gly Gln Leu Ala Ala Asp Ile 
1               5                   10                  15      


His Gln Ala Leu Arg Tyr Lys Glu Leu Lys Leu Pro Ser Tyr Lys Gly 
            20                  25                  30          


Gln Ser Pro Gln Leu Ser Leu Arg Arg Tyr Phe Ala Asp Leu Ile Ala 
        35                  40                  45              


Ile Val Ser Asn Arg Phe Thr Leu Cys Pro Ser Ala Arg His Leu Ala 
    50                  55                  60                  


Val Tyr Leu Leu Asp Leu Phe Met Asp Arg Tyr Asp Ile Ser Ile Gln 
65                  70                  75                  80  


Gln Leu His Leu Val Ala Leu Ser Cys Leu Leu Leu Ala Ser Lys Phe 
                85                  90                  95      


Glu Glu Lys Glu Asp Ser Val Pro Lys Leu Glu Gln Leu Asn Ser Leu 
            100                 105                 110         


Gly Cys Met Thr Asn Met Asn Leu Val Leu Thr Lys Gln Asn Leu Leu 
        115                 120                 125             


His Met Glu Leu Leu Leu Leu Glu Thr Phe Gln Trp Asn Leu Cys Leu 
    130                 135                 140                 


Pro Thr Ala Ala His Phe Ile Glu Tyr Tyr Leu Ser Glu Ala Val His 
145                 150                 155                 160 


Glu Thr Asp Leu His Asp Gly Trp Pro Met Ile Cys Leu Glu Lys Thr 
                165                 170                 175     


Lys Leu Tyr Met Ala Lys Tyr Ala Asp Tyr Phe Leu Glu Val Ser Leu 
            180                 185                 190         


Gln Val Ala Ala Ala Cys Val Ala Ser Ser Arg Ile Ile Leu Arg Leu 
        195                 200                 205             


Ser Pro Thr Trp Pro Thr Arg Leu His Arg Leu Thr Ala Tyr Ser Trp 
    210                 215                 220                 


Asp Phe Leu Val Gln Cys Ile Glu Arg Leu Leu Ile Ala His Asp Asn 
225                 230                 235                 240 


Asp Val Lys Glu Ala Asn Lys Gln Arg Gly Gln Ala Gly Pro Gln Ser 
                245                 250                 255     


Ala Gln Leu Ser Val Phe Gln Thr Ala Ser Gln Pro Ser Arg Pro Val 
            260                 265                 270         


His Phe Gln Gln Pro Gln Tyr Leu His Gln Thr His Gln Thr Ser Leu 
        275                 280                 285             


Gln Tyr Arg His Pro Thr Ser Glu Gln Pro Ser Cys Gln Gln Ile Val 
    290                 295                 300                 


Ser Thr Thr His Thr Ser Ser Tyr Thr Leu Gln Thr Cys Pro Ala Gly 
305                 310                 315                 320 


Phe Gln Thr Ser Val Gln Gly Leu Gly His Met Gln Thr Gly Val Gly 
                325                 330                 335     


Met Ser Leu Ala Ile Pro Val Glu Val Lys Pro Cys Leu Ser Val Ser 
            340                 345                 350         


Tyr Asn Arg Ser Tyr Gln Ile Asn Glu His Tyr Pro Cys Ile Thr Pro 
        355                 360                 365             


Cys Phe Glu Arg 
    370         


<210>  3700
<211>  459
<212>  PRT
<213>  homo sapiens

<400>  3700

Met Asp Gly Phe Tyr Asp Gln Gln Val Pro Tyr Met Val Thr Asn Ser 
1               5                   10                  15      


Gln Arg Gly Arg Asn Cys Asn Glu Lys Pro Thr Asn Val Arg Lys Arg 
            20                  25                  30          


Lys Phe Ile Asn Arg Asp Leu Ala His Asp Ser Glu Glu Leu Phe Gln 
        35                  40                  45              


Asp Leu Ser Gln Leu Gln Glu Thr Trp Leu Ala Glu Val Ala Phe His 
    50                  55                  60                  


Gly Leu Pro Leu Lys Ile Lys Lys Glu Pro His Ser Pro Cys Ser Glu 
65                  70                  75                  80  


Ile Ser Ser Ala Cys Ser Gln Glu Gln Pro Phe Lys Phe Ser Tyr Gly 
                85                  90                  95      


Glu Lys Cys Leu Tyr Asn Val Ser Ala Tyr Asp Gln Lys Pro Gln Val 
            100                 105                 110         


Gly Met Arg Pro Ser Asn Pro Pro Thr Pro Ser Ser Thr Pro Val Ser 
        115                 120                 125             


Pro Leu His His Ala Ser Pro Asn Ser Thr His Thr Pro Lys Pro Asp 
    130                 135                 140                 


Arg Ala Phe Pro Ala His Leu Pro Pro Ser Gln Ser Ile Pro Asp Ser 
145                 150                 155                 160 


Ser Tyr Pro Met Asp His Arg Phe Arg Arg Gln Leu Ser Glu Pro Cys 
                165                 170                 175     


Asn Ser Phe Pro Pro Leu Pro Thr Met Pro Arg Glu Gly Arg Pro Met 
            180                 185                 190         


Tyr Gln Arg Gln Met Ser Glu Pro Asn Ile Pro Phe Pro Pro Gln Gly 
        195                 200                 205             


Phe Lys Gln Glu Tyr His Asp Pro Val Tyr Glu His Asn Thr Met Val 
    210                 215                 220                 


Gly Ser Ala Ala Ser Gln Ser Phe Pro Pro Pro Leu Met Ile Lys Gln 
225                 230                 235                 240 


Glu Pro Arg Asp Phe Ala Tyr Asp Ser Glu Val Pro Ser Cys His Ser 
                245                 250                 255     


Ile Tyr Met Arg Gln Glu Gly Phe Leu Ala His Pro Ser Arg Thr Glu 
            260                 265                 270         


Gly Cys Met Phe Glu Lys Gly Pro Arg Gln Phe Tyr Asp Asp Thr Cys 
        275                 280                 285             


Val Val Pro Glu Lys Phe Asp Gly Asp Ile Lys Gln Glu Pro Gly Met 
    290                 295                 300                 


Tyr Arg Glu Gly Pro Thr Tyr Gln Arg Arg Gly Ser Leu Gln Leu Trp 
305                 310                 315                 320 


Gln Phe Leu Val Ala Leu Leu Asp Asp Pro Ser Asn Ser His Phe Ile 
                325                 330                 335     


Ala Trp Thr Gly Arg Gly Met Glu Phe Lys Leu Ile Glu Pro Glu Glu 
            340                 345                 350         


Val Ala Arg Arg Trp Gly Ile Gln Lys Asn Arg Pro Ala Met Asn Tyr 
        355                 360                 365             


Asp Lys Leu Ser Arg Ser Leu Arg Tyr Tyr Tyr Glu Lys Gly Ile Met 
    370                 375                 380                 


Gln Lys Val Ala Gly Glu Arg Tyr Val Tyr Lys Phe Val Cys Asp Pro 
385                 390                 395                 400 


Glu Ala Leu Phe Ser Met Ala Phe Pro Asp Asn Gln Arg Pro Leu Leu 
                405                 410                 415     


Lys Thr Asp Met Glu Arg His Ile Asn Glu Glu Asp Thr Val Pro Leu 
            420                 425                 430         


Ser His Phe Asp Glu Ser Met Ala Tyr Met Pro Glu Gly Gly Cys Cys 
        435                 440                 445             


Asn Pro His Pro Tyr Asn Glu Gly Tyr Val Tyr 
    450                 455                 


<210>  3701
<211>  423
<212>  PRT
<213>  homo sapiens

<400>  3701

Met Ala Leu Lys Val Leu Leu Glu Gln Glu Lys Thr Phe Phe Thr Leu 
1               5                   10                  15      


Leu Val Leu Leu Gly Tyr Leu Ser Cys Lys Val Thr Cys Glu Ser Gly 
            20                  25                  30          


Asp Cys Arg Gln Gln Glu Phe Arg Asp Arg Ser Gly Asn Cys Val Pro 
        35                  40                  45              


Cys Asn Gln Cys Gly Pro Gly Met Glu Leu Ser Lys Glu Cys Gly Phe 
    50                  55                  60                  


Gly Tyr Gly Glu Asp Ala Gln Cys Val Thr Cys Arg Leu His Arg Phe 
65                  70                  75                  80  


Lys Glu Asp Trp Gly Phe Gln Lys Cys Lys Pro Cys Leu Asp Cys Ala 
                85                  90                  95      


Val Val Asn Arg Phe Gln Lys Ala Asn Cys Ser Ala Thr Ser Asp Ala 
            100                 105                 110         


Ile Cys Gly Asp Cys Leu Pro Gly Phe Tyr Arg Lys Thr Lys Leu Val 
        115                 120                 125             


Gly Phe Gln Asp Met Glu Cys Val Pro Cys Gly Asp Pro Pro Pro Pro 
    130                 135                 140                 


Tyr Glu Pro His Cys Ala Ser Lys Val Asn Leu Val Lys Ile Ala Ser 
145                 150                 155                 160 


Thr Ala Ser Ser Pro Arg Asp Thr Ala Leu Ala Ala Val Ile Cys Ser 
                165                 170                 175     


Ala Leu Ala Thr Val Leu Leu Ala Leu Leu Ile Leu Cys Val Ile Tyr 
            180                 185                 190         


Cys Lys Arg Gln Phe Met Glu Lys Lys Pro Ser Trp Ser Leu Arg Ser 
        195                 200                 205             


Gln Asp Ile Gln Tyr Asn Gly Ser Glu Leu Ser Cys Phe Asp Arg Pro 
    210                 215                 220                 


Gln Leu His Glu Tyr Ala His Arg Ala Cys Cys Gln Cys Arg Arg Asp 
225                 230                 235                 240 


Ser Val Gln Thr Cys Gly Pro Val Arg Leu Leu Pro Ser Met Cys Cys 
                245                 250                 255     


Glu Glu Ala Cys Ser Pro Asn Pro Ala Thr Leu Gly Cys Gly Val His 
            260                 265                 270         


Ser Ala Ala Ser Leu Gln Ala Arg Asn Ala Gly Pro Ala Gly Glu Met 
        275                 280                 285             


Val Pro Thr Phe Phe Gly Ser Leu Thr Gln Ser Ile Cys Gly Glu Phe 
    290                 295                 300                 


Ser Asp Ala Trp Pro Leu Met Gln Asn Pro Met Gly Gly Asp Asn Ile 
305                 310                 315                 320 


Ser Phe Cys Asp Ser Tyr Pro Glu Leu Thr Gly Glu Asp Ile His Ser 
                325                 330                 335     


Leu Asn Pro Glu Leu Glu Ser Ser Thr Ser Leu Asp Ser Asn Ser Ser 
            340                 345                 350         


Gln Asp Leu Val Gly Gly Ala Val Pro Val Gln Ser His Ser Glu Asn 
        355                 360                 365             


Phe Thr Ala Ala Thr Asp Leu Ser Arg Tyr Asn Asn Thr Leu Val Glu 
    370                 375                 380                 


Ser Ala Ser Thr Gln Asp Ala Leu Thr Met Arg Ser Gln Leu Asp Gln 
385                 390                 395                 400 


Glu Ser Gly Ala Val Ile His Pro Ala Thr Gln Thr Ser Leu Gln Val 
                405                 410                 415     


Arg Gln Arg Leu Gly Ser Leu 
            420             


<210>  3702
<211>  342
<212>  PRT
<213>  homo sapiens

<400>  3702

Met Asp Leu Trp Asn Trp Asp Glu Ala Ser Pro Gln Glu Val Pro Pro 
1               5                   10                  15      


Gly Asn Lys Leu Ala Gly Leu Glu Gly Ala Lys Leu Gly Phe Cys Phe 
            20                  25                  30          


Pro Asp Leu Ala Leu Gln Gly Asp Thr Pro Thr Ala Thr Ala Glu Thr 
        35                  40                  45              


Cys Trp Lys Gly Thr Ser Ser Ser Leu Ala Ser Phe Pro Gln Leu Asp 
    50                  55                  60                  


Trp Gly Ser Ala Leu Leu His Pro Glu Val Pro Trp Gly Ala Glu Pro 
65                  70                  75                  80  


Asp Ser Gln Ala Leu Pro Trp Ser Gly Asp Trp Thr Asp Met Ala Cys 
                85                  90                  95      


Thr Ala Trp Asp Ser Trp Ser Gly Ala Ser Gln Thr Leu Gly Pro Ala 
            100                 105                 110         


Pro Leu Gly Pro Gly Pro Ile Pro Ala Ala Gly Ser Glu Gly Ala Ala 
        115                 120                 125             


Gly Gln Asn Cys Val Pro Val Ala Gly Glu Ala Thr Ser Trp Ser Arg 
    130                 135                 140                 


Ala Gln Ala Ala Gly Ser Asn Thr Ser Trp Asp Cys Ser Val Gly Pro 
145                 150                 155                 160 


Asp Gly Asp Thr Tyr Trp Gly Ser Gly Leu Gly Gly Glu Pro Arg Thr 
                165                 170                 175     


Asp Cys Thr Ile Ser Trp Gly Gly Pro Ala Gly Pro Asp Cys Thr Thr 
            180                 185                 190         


Ser Trp Asn Pro Gly Leu His Ala Gly Gly Thr Thr Ser Leu Lys Arg 
        195                 200                 205             


Tyr Gln Ser Ser Ala Leu Thr Val Cys Ser Glu Pro Ser Pro Gln Ser 
    210                 215                 220                 


Asp Arg Ala Ser Leu Ala Arg Cys Pro Lys Thr Asn His Arg Gly Pro 
225                 230                 235                 240 


Ile Gln Leu Trp Gln Phe Leu Leu Glu Leu Leu His Asp Gly Ala Arg 
                245                 250                 255     


Ser Ser Cys Ile Arg Trp Thr Gly Asn Ser Arg Glu Phe Gln Leu Cys 
            260                 265                 270         


Asp Pro Lys Glu Val Ala Arg Leu Trp Gly Glu Arg Lys Arg Lys Pro 
        275                 280                 285             


Gly Met Asn Tyr Glu Lys Leu Ser Arg Gly Leu Arg Tyr Tyr Tyr Arg 
    290                 295                 300                 


Arg Asp Ile Val Arg Lys Ser Gly Gly Arg Lys Tyr Thr Tyr Arg Phe 
305                 310                 315                 320 


Gly Gly Arg Val Pro Ser Leu Ala Tyr Pro Asp Cys Ala Gly Gly Gly 
                325                 330                 335     


Arg Gly Ala Glu Thr Gln 
            340         


<210>  3703
<211>  324
<212>  PRT
<213>  homo sapiens

<400>  3703

Met Asp Ala Pro Arg Gln Val Val Asn Phe Gly Pro Gly Pro Ala Lys 
1               5                   10                  15      


Leu Pro His Ser Val Leu Leu Glu Ile Gln Lys Glu Leu Leu Asp Tyr 
            20                  25                  30          


Lys Gly Val Gly Ile Ser Val Leu Glu Met Ser His Arg Ser Ser Asp 
        35                  40                  45              


Phe Ala Lys Ile Ile Asn Asn Thr Glu Asn Leu Val Arg Glu Leu Leu 
    50                  55                  60                  


Ala Val Pro Asp Asn Tyr Lys Val Ile Phe Leu Gln Gly Gly Gly Cys 
65                  70                  75                  80  


Gly Gln Phe Ser Ala Val Pro Leu Asn Leu Ile Gly Leu Lys Ala Gly 
                85                  90                  95      


Arg Cys Ala Asp Tyr Val Val Thr Gly Ala Trp Ser Ala Lys Ala Ala 
            100                 105                 110         


Glu Glu Ala Lys Lys Phe Gly Thr Ile Asn Ile Val His Pro Lys Leu 
        115                 120                 125             


Gly Ser Tyr Thr Lys Ile Pro Asp Pro Ser Thr Trp Asn Leu Asn Pro 
    130                 135                 140                 


Asp Ala Ser Tyr Val Tyr Tyr Cys Ala Asn Glu Thr Val His Gly Val 
145                 150                 155                 160 


Glu Phe Asp Phe Ile Pro Asp Val Lys Gly Ala Val Leu Val Cys Asp 
                165                 170                 175     


Met Ser Ser Asn Phe Leu Ser Lys Pro Val Asp Val Ser Lys Phe Gly 
            180                 185                 190         


Val Ile Phe Ala Gly Ala Gln Lys Asn Val Gly Ser Ala Gly Val Thr 
        195                 200                 205             


Val Val Ile Val Arg Asp Asp Leu Leu Gly Phe Ala Leu Arg Glu Cys 
    210                 215                 220                 


Pro Ser Val Leu Glu Tyr Lys Val Gln Ala Gly Asn Ser Ser Leu Tyr 
225                 230                 235                 240 


Asn Thr Pro Pro Cys Phe Ser Ile Tyr Val Met Gly Leu Val Leu Glu 
                245                 250                 255     


Trp Ile Lys Asn Asn Gly Gly Ala Ala Ala Met Glu Lys Leu Ser Ser 
            260                 265                 270         


Ile Lys Ser Gln Thr Ile Tyr Glu Ile Ile Asp Asn Ser Gln Gly Phe 
        275                 280                 285             


Tyr Val Ser Val Gly Gly Ile Arg Ala Ser Leu Tyr Asn Ala Val Thr 
    290                 295                 300                 


Ile Glu Asp Val Gln Lys Leu Ala Ala Phe Met Lys Lys Phe Leu Glu 
305                 310                 315                 320 


Met His Gln Leu 
                


<210>  3704
<211>  1226
<212>  PRT
<213>  homo sapiens

<400>  3704

Met Lys Ala Leu Asp Glu Pro Pro Tyr Leu Thr Val Gly Thr Asp Val 
1               5                   10                  15      


Ser Ala Lys Tyr Arg Gly Ala Phe Cys Glu Ala Lys Ile Lys Thr Ala 
            20                  25                  30          


Lys Arg Leu Val Lys Val Lys Val Thr Phe Arg His Asp Ser Ser Thr 
        35                  40                  45              


Val Glu Val Gln Asp Asp His Ile Lys Gly Pro Leu Lys Val Gly Ala 
    50                  55                  60                  


Ile Val Glu Val Lys Asn Leu Asp Gly Ala Tyr Gln Glu Ala Val Ile 
65                  70                  75                  80  


Asn Lys Leu Thr Asp Ala Ser Trp Tyr Thr Val Val Phe Asp Asp Gly 
                85                  90                  95      


Asp Glu Lys Thr Leu Arg Arg Ser Ser Leu Cys Leu Lys Gly Glu Arg 
            100                 105                 110         


His Phe Ala Glu Ser Glu Thr Leu Asp Gln Leu Pro Leu Thr Asn Pro 
        115                 120                 125             


Glu His Phe Gly Thr Pro Val Ile Gly Lys Lys Thr Asn Arg Gly Arg 
    130                 135                 140                 


Arg Ser Asn His Ile Pro Glu Glu Glu Ser Ser Ser Ser Ser Ser Asp 
145                 150                 155                 160 


Glu Asp Glu Asp Asp Arg Lys Gln Ile Asp Glu Leu Leu Gly Lys Val 
                165                 170                 175     


Val Cys Val Asp Tyr Ile Ser Leu Asp Lys Lys Lys Ala Leu Trp Phe 
            180                 185                 190         


Pro Ala Leu Val Val Cys Pro Asp Cys Ser Asp Glu Ile Ala Val Lys 
        195                 200                 205             


Lys Asp Asn Ile Leu Val Arg Ser Phe Lys Asp Gly Lys Phe Thr Ser 
    210                 215                 220                 


Val Pro Arg Lys Asp Val His Glu Ile Thr Ser Asp Thr Ala Pro Lys 
225                 230                 235                 240 


Pro Asp Ala Val Leu Lys Gln Ala Phe Glu Gln Ala Leu Glu Phe His 
                245                 250                 255     


Lys Ser Arg Thr Ile Pro Ala Asn Trp Lys Thr Glu Leu Lys Glu Asp 
            260                 265                 270         


Ser Ser Ser Ser Glu Ala Glu Glu Glu Glu Glu Glu Glu Asp Asp Glu 
        275                 280                 285             


Lys Glu Lys Glu Asp Asn Ser Ser Glu Glu Glu Glu Glu Ile Glu Pro 
    290                 295                 300                 


Phe Pro Glu Glu Arg Glu Asn Phe Leu Gln Gln Leu Tyr Lys Phe Met 
305                 310                 315                 320 


Glu Asp Arg Gly Thr Pro Ile Asn Lys Arg Pro Val Leu Gly Tyr Arg 
                325                 330                 335     


Asn Leu Asn Leu Phe Lys Leu Phe Arg Leu Val His Lys Leu Gly Gly 
            340                 345                 350         


Phe Asp Asn Ile Glu Ser Gly Ala Val Trp Lys Gln Val Tyr Gln Asp 
        355                 360                 365             


Leu Gly Ile Pro Val Leu Asn Ser Ala Ala Gly Tyr Asn Val Lys Cys 
    370                 375                 380                 


Ala Tyr Lys Lys Tyr Leu Tyr Gly Phe Glu Glu Tyr Cys Arg Ser Ala 
385                 390                 395                 400 


Asn Ile Glu Phe Gln Met Ala Leu Pro Glu Lys Val Val Asn Lys Gln 
                405                 410                 415     


Cys Lys Glu Cys Glu Asn Val Lys Glu Ile Lys Val Lys Glu Glu Asn 
            420                 425                 430         


Glu Thr Glu Ile Lys Glu Ile Lys Met Glu Glu Glu Arg Asn Ile Ile 
        435                 440                 445             


Pro Arg Glu Glu Lys Pro Ile Glu Asp Glu Ile Glu Arg Lys Glu Asn 
    450                 455                 460                 


Ile Lys Pro Ser Leu Gly Ser Lys Lys Asn Leu Leu Glu Ser Ile Pro 
465                 470                 475                 480 


Thr His Ser Asp Gln Glu Lys Glu Val Asn Ile Lys Lys Pro Glu Asp 
                485                 490                 495     


Asn Glu Asn Leu Asp Asp Lys Asp Asp Asp Thr Thr Arg Val Asp Glu 
            500                 505                 510         


Ser Leu Asn Ile Lys Val Glu Ala Glu Glu Glu Lys Ala Lys Ser Gly 
        515                 520                 525             


Tyr Asp Glu Trp Ile Lys Ala Asp Lys Ile Val Arg Pro Ala Asp Lys 
    530                 535                 540                 


Asn Val Pro Lys Ile Lys His Arg Lys Lys Ile Lys Asn Lys Leu Asp 
545                 550                 555                 560 


Lys Glu Lys Asp Lys Asp Glu Lys Tyr Ser Pro Lys Asn Cys Lys Leu 
                565                 570                 575     


Arg Arg Leu Ser Lys Pro Pro Phe Gln Thr Asn Pro Ser Pro Glu Met 
            580                 585                 590         


Val Ser Lys Leu Asp Leu Thr Asp Ala Lys Asn Ser Asp Thr Ala His 
        595                 600                 605             


Ile Lys Ser Ile Glu Ile Thr Ser Ile Leu Asn Gly Leu Gln Ala Ser 
    610                 615                 620                 


Glu Ser Ser Ala Glu Asp Ser Glu Gln Glu Asp Glu Arg Gly Ala Gln 
625                 630                 635                 640 


Asp Met Asp Asn Asn Gly Lys Glu Glu Ser Lys Ile Asp His Leu Thr 
                645                 650                 655     


Asn Asn Arg Asn Asp Leu Ile Ser Lys Glu Glu Gln Asn Ser Ser Ser 
            660                 665                 670         


Leu Leu Glu Glu Asn Lys Val His Ala Asp Leu Val Ile Ser Lys Pro 
        675                 680                 685             


Val Ser Lys Ser Pro Glu Arg Leu Arg Lys Asp Ile Glu Val Leu Ser 
    690                 695                 700                 


Glu Asp Thr Asp Tyr Glu Glu Asp Glu Val Thr Lys Lys Arg Lys Asp 
705                 710                 715                 720 


Val Lys Lys Asp Thr Thr Asp Lys Ser Ser Lys Pro Gln Ile Lys Arg 
                725                 730                 735     


Gly Lys Arg Arg Tyr Cys Asn Thr Glu Glu Cys Leu Lys Thr Gly Ser 
            740                 745                 750         


Pro Gly Lys Lys Glu Glu Lys Ala Lys Asn Lys Glu Ser Leu Cys Met 
        755                 760                 765             


Glu Asn Ser Ser Asn Ser Ser Ser Asp Glu Asp Glu Glu Glu Thr Lys 
    770                 775                 780                 


Ala Lys Met Thr Pro Thr Lys Lys Tyr Asn Gly Leu Glu Glu Lys Arg 
785                 790                 795                 800 


Lys Ser Leu Arg Thr Thr Gly Phe Tyr Ser Gly Phe Ser Glu Val Ala 
                805                 810                 815     


Glu Lys Arg Ile Lys Leu Leu Asn Asn Ser Asp Glu Arg Leu Gln Asn 
            820                 825                 830         


Ser Arg Ala Lys Asp Arg Lys Asp Val Trp Ser Ser Ile Gln Gly Gln 
        835                 840                 845             


Trp Pro Lys Lys Thr Leu Lys Glu Leu Phe Ser Asp Ser Asp Thr Glu 
    850                 855                 860                 


Ala Ala Ala Ser Pro Pro His Pro Ala Pro Glu Glu Gly Val Ala Glu 
865                 870                 875                 880 


Glu Ser Leu Gln Thr Val Ala Glu Glu Glu Ser Cys Ser Pro Ser Val 
                885                 890                 895     


Glu Leu Glu Lys Pro Pro Pro Val Asn Val Asp Ser Lys Pro Ile Glu 
            900                 905                 910         


Glu Lys Thr Val Glu Val Asn Asp Arg Lys Ala Glu Phe Pro Ser Ser 
        915                 920                 925             


Gly Ser Asn Ser Val Leu Asn Thr Pro Pro Thr Thr Pro Glu Ser Pro 
    930                 935                 940                 


Ser Ser Val Thr Val Thr Glu Gly Ser Arg Gln Gln Ser Ser Val Thr 
945                 950                 955                 960 


Val Ser Glu Pro Leu Ala Pro Asn Gln Glu Glu Val Arg Ser Ile Lys 
                965                 970                 975     


Ser Glu Thr Asp Ser Thr Ile Glu Val Asp Ser Val Ala Gly Glu Leu 
            980                 985                 990         


Gln Asp Leu Gln Ser Glu Gly Asn  Ser Ser Pro Ala Gly  Phe Asp Ala 
        995                 1000                 1005             


Ser Val  Ser Ser Ser Ser Ser  Asn Gln Pro Glu Pro  Glu His Pro 
    1010                 1015                 1020             


Glu Lys  Ala Cys Thr Gly Gln  Lys Arg Val Lys Asp  Ala Gln Gly 
    1025                 1030                 1035             


Gly Gly  Ser Ser Ser Lys Lys  Gln Lys Arg Ser His  Lys Ala Thr 
    1040                 1045                 1050             


Val Val  Asn Asn Lys Lys Lys  Gly Lys Gly Thr Asn  Ser Ser Asp 
    1055                 1060                 1065             


Ser Glu  Glu Leu Ser Ala Gly  Glu Ser Ile Thr Lys  Ser Gln Pro 
    1070                 1075                 1080             


Val Lys  Ser Val Ser Thr Gly  Met Lys Ser His Ser  Thr Lys Ser 
    1085                 1090                 1095             


Pro Ala  Arg Thr Gln Ser Pro  Gly Lys Cys Gly Lys  Asn Gly Asp 
    1100                 1105                 1110             


Lys Asp  Pro Asp Leu Lys Glu  Pro Ser Asn Arg Leu  Pro Lys Val 
    1115                 1120                 1125             


Tyr Lys  Trp Ser Phe Gln Met  Ser Asp Leu Glu Asn  Met Thr Ser 
    1130                 1135                 1140             


Ala Glu  Arg Ile Thr Ile Leu  Gln Glu Lys Leu Gln  Glu Ile Arg 
    1145                 1150                 1155             


Lys His  Tyr Leu Ser Leu Lys  Ser Glu Val Ala Ser  Ile Asp Arg 
    1160                 1165                 1170             


Arg Arg  Lys Arg Leu Lys Lys  Lys Glu Arg Glu Ser  Ala Ala Thr 
    1175                 1180                 1185             


Ser Ser  Ser Ser Ser Ser Pro  Ser Ser Ser Ser Ile  Thr Ala Ala 
    1190                 1195                 1200             


Val Met  Leu Thr Leu Ala Glu  Pro Ser Met Ser Ser  Ala Ser Gln 
    1205                 1210                 1215             


Asn Gly  Met Ser Val Glu Cys  Arg 
    1220                 1225     


<210>  3705
<211>  916
<212>  PRT
<213>  homo sapiens

<400>  3705

Met Ser Tyr Thr Leu Asp Ser Leu Gly Asn Pro Ser Ala Tyr Arg Arg 
1               5                   10                  15      


Val Thr Glu Thr Arg Ser Ser Phe Ser Arg Val Ser Gly Ser Pro Ser 
            20                  25                  30          


Ser Gly Phe Arg Ser Gln Ser Trp Ser Arg Gly Ser Pro Ser Thr Val 
        35                  40                  45              


Ser Ser Ser Tyr Lys Arg Ser Met Leu Ala Pro Arg Leu Ala Tyr Ser 
    50                  55                  60                  


Ser Ala Met Leu Ser Ser Ala Glu Ser Ser Leu Asp Phe Ser Gln Ser 
65                  70                  75                  80  


Ser Ser Leu Leu Asn Gly Gly Ser Gly Pro Gly Gly Asp Tyr Lys Leu 
                85                  90                  95      


Ser Arg Ser Asn Glu Lys Glu Gln Leu Gln Gly Leu Asn Asp Arg Phe 
            100                 105                 110         


Ala Gly Tyr Ile Glu Lys Val His Tyr Leu Glu Gln Gln Asn Lys Glu 
        115                 120                 125             


Ile Glu Ala Glu Ile Gln Ala Leu Arg Gln Lys Gln Ala Ser His Ala 
    130                 135                 140                 


Gln Leu Gly Asp Ala Tyr Asp Gln Glu Ile Arg Glu Leu Arg Ala Thr 
145                 150                 155                 160 


Leu Glu Met Val Asn His Glu Lys Ala Gln Val Gln Leu Asp Ser Asp 
                165                 170                 175     


His Leu Glu Glu Asp Ile His Arg Leu Lys Glu Arg Phe Glu Glu Glu 
            180                 185                 190         


Ala Arg Leu Arg Asp Asp Thr Glu Ala Ala Ile Arg Ala Leu Arg Lys 
        195                 200                 205             


Asp Ile Glu Glu Ala Ser Leu Val Lys Val Glu Leu Asp Lys Lys Val 
    210                 215                 220                 


Gln Ser Leu Gln Asp Glu Val Ala Phe Leu Arg Ser Asn His Glu Glu 
225                 230                 235                 240 


Glu Val Ala Asp Leu Leu Ala Gln Ile Gln Ala Ser His Ile Thr Val 
                245                 250                 255     


Glu Arg Lys Asp Tyr Leu Lys Thr Asp Ile Ser Thr Ala Leu Lys Glu 
            260                 265                 270         


Ile Arg Ser Gln Leu Glu Ser His Ser Asp Gln Asn Met His Gln Ala 
        275                 280                 285             


Glu Glu Trp Phe Lys Cys Arg Tyr Ala Lys Leu Thr Glu Ala Ala Glu 
    290                 295                 300                 


Gln Asn Lys Glu Ala Ile Arg Ser Ala Lys Glu Glu Ile Ala Glu Tyr 
305                 310                 315                 320 


Arg Arg Gln Leu Gln Ser Lys Ser Ile Glu Leu Glu Ser Val Arg Gly 
                325                 330                 335     


Thr Lys Glu Ser Leu Glu Arg Gln Leu Ser Asp Ile Glu Glu Arg His 
            340                 345                 350         


Asn His Asp Leu Ser Ser Tyr Gln Asp Thr Ile Gln Gln Leu Glu Asn 
        355                 360                 365             


Glu Leu Arg Gly Thr Lys Trp Glu Met Ala Arg His Leu Arg Glu Tyr 
    370                 375                 380                 


Gln Asp Leu Leu Asn Val Lys Met Ala Leu Asp Ile Glu Ile Ala Ala 
385                 390                 395                 400 


Tyr Arg Lys Leu Leu Glu Gly Glu Glu Thr Arg Phe Ser Thr Phe Ala 
                405                 410                 415     


Gly Ser Ile Thr Gly Pro Leu Tyr Thr His Arg Pro Pro Ile Thr Ile 
            420                 425                 430         


Ser Ser Lys Ile Gln Lys Pro Lys Val Glu Ala Pro Lys Leu Lys Val 
        435                 440                 445             


Gln His Lys Phe Val Glu Glu Ile Ile Glu Glu Thr Lys Val Glu Asp 
    450                 455                 460                 


Glu Lys Ser Glu Met Glu Glu Ala Leu Thr Ala Ile Thr Glu Glu Leu 
465                 470                 475                 480 


Ala Val Ser Met Lys Glu Glu Lys Lys Glu Ala Ala Glu Glu Lys Glu 
                485                 490                 495     


Glu Glu Pro Glu Ala Glu Glu Glu Glu Val Ala Ala Lys Lys Ser Pro 
            500                 505                 510         


Val Lys Ala Thr Ala Pro Glu Val Lys Glu Glu Glu Gly Glu Lys Glu 
        515                 520                 525             


Glu Glu Glu Gly Gln Glu Glu Glu Glu Glu Glu Asp Glu Gly Ala Lys 
    530                 535                 540                 


Ser Asp Gln Ala Glu Glu Gly Gly Ser Glu Lys Glu Gly Ser Ser Glu 
545                 550                 555                 560 


Lys Glu Glu Gly Glu Gln Glu Glu Gly Glu Thr Glu Ala Glu Ala Glu 
                565                 570                 575     


Gly Glu Glu Ala Glu Ala Lys Glu Glu Lys Lys Val Glu Glu Lys Ser 
            580                 585                 590         


Glu Glu Val Ala Thr Lys Glu Glu Leu Val Ala Asp Ala Lys Val Glu 
        595                 600                 605             


Lys Pro Glu Lys Ala Lys Ser Pro Val Pro Lys Ser Pro Val Glu Glu 
    610                 615                 620                 


Lys Gly Lys Ser Pro Val Pro Lys Ser Pro Val Glu Glu Lys Gly Lys 
625                 630                 635                 640 


Ser Pro Val Pro Lys Ser Pro Val Glu Glu Lys Gly Lys Ser Pro Val 
                645                 650                 655     


Pro Lys Ser Pro Val Glu Glu Lys Gly Lys Ser Pro Val Ser Lys Ser 
            660                 665                 670         


Pro Val Glu Glu Lys Ala Lys Ser Pro Val Pro Lys Ser Pro Val Glu 
        675                 680                 685             


Glu Ala Lys Ser Lys Ala Glu Val Gly Lys Gly Glu Gln Lys Glu Glu 
    690                 695                 700                 


Glu Glu Lys Glu Val Lys Glu Ala Pro Lys Glu Glu Lys Val Glu Lys 
705                 710                 715                 720 


Lys Glu Glu Lys Pro Lys Asp Val Pro Glu Lys Lys Lys Ala Glu Ser 
                725                 730                 735     


Pro Val Lys Glu Glu Ala Val Ala Glu Val Val Thr Ile Thr Lys Ser 
            740                 745                 750         


Val Lys Val His Leu Glu Lys Glu Thr Lys Glu Glu Gly Lys Pro Leu 
        755                 760                 765             


Gln Gln Glu Lys Glu Lys Glu Lys Ala Gly Gly Glu Gly Gly Ser Glu 
    770                 775                 780                 


Glu Glu Gly Ser Asp Lys Gly Ala Lys Gly Ser Arg Lys Glu Asp Ile 
785                 790                 795                 800 


Ala Val Asn Gly Glu Val Glu Gly Lys Glu Glu Val Glu Gln Glu Thr 
                805                 810                 815     


Lys Glu Lys Gly Ser Gly Arg Glu Glu Glu Lys Gly Val Val Thr Asn 
            820                 825                 830         


Gly Leu Asp Leu Ser Pro Ala Asp Glu Lys Lys Gly Gly Asp Lys Ser 
        835                 840                 845             


Glu Glu Lys Val Val Val Thr Lys Thr Val Glu Lys Ile Thr Ser Glu 
    850                 855                 860                 


Gly Gly Asp Gly Ala Thr Lys Tyr Ile Thr Lys Ser Val Thr Val Thr 
865                 870                 875                 880 


Gln Lys Val Glu Glu His Glu Glu Thr Phe Glu Glu Lys Leu Val Ser 
                885                 890                 895     


Thr Lys Lys Val Glu Lys Val Thr Ser His Ala Ile Val Lys Glu Val 
            900                 905                 910         


Thr Gln Ser Asp 
        915     


<210>  3706
<211>  510
<212>  PRT
<213>  homo sapiens

<400>  3706

Met Asp Gly Phe Tyr Asp Gln Gln Val Pro Phe Met Val Pro Gly Lys 
1               5                   10                  15      


Ser Arg Ser Glu Glu Cys Arg Gly Arg Pro Val Ile Asp Arg Lys Arg 
            20                  25                  30          


Lys Phe Leu Asp Thr Asp Leu Ala His Asp Ser Glu Glu Leu Phe Gln 
        35                  40                  45              


Asp Leu Ser Gln Leu Gln Glu Ala Trp Leu Ala Glu Ala Gln Val Pro 
    50                  55                  60                  


Asp Asp Glu Gln Phe Val Pro Asp Phe Gln Ser Asp Asn Leu Val Leu 
65                  70                  75                  80  


His Ala Pro Pro Pro Thr Lys Ile Lys Arg Glu Leu His Ser Pro Ser 
                85                  90                  95      


Ser Glu Leu Ser Ser Cys Ser His Glu Gln Ala Leu Gly Ala Asn Tyr 
            100                 105                 110         


Gly Glu Lys Cys Leu Tyr Asn Tyr Cys Ala Tyr Asp Arg Lys Pro Pro 
        115                 120                 125             


Ser Gly Phe Lys Pro Leu Thr Pro Pro Thr Thr Pro Leu Ser Pro Thr 
    130                 135                 140                 


His Gln Asn Pro Leu Phe Pro Pro Pro Gln Ala Thr Leu Pro Thr Ser 
145                 150                 155                 160 


Gly His Ala Pro Ala Ala Gly Pro Val Gln Gly Val Gly Pro Ala Pro 
                165                 170                 175     


Ala Pro His Ser Leu Pro Glu Pro Gly Pro Gln Gln Gln Thr Phe Ala 
            180                 185                 190         


Val Pro Arg Pro Pro His Gln Pro Leu Gln Met Pro Lys Met Met Pro 
        195                 200                 205             


Glu Asn Gln Tyr Pro Ser Glu Gln Arg Phe Gln Arg Gln Leu Ser Glu 
    210                 215                 220                 


Pro Cys His Pro Phe Pro Pro Gln Pro Gly Val Pro Gly Asp Asn Arg 
225                 230                 235                 240 


Pro Ser Tyr His Arg Gln Met Ser Glu Pro Ile Val Pro Ala Ala Pro 
                245                 250                 255     


Pro Pro Pro Gln Gly Phe Lys Gln Glu Tyr His Asp Pro Leu Tyr Glu 
            260                 265                 270         


His Gly Val Pro Gly Met Pro Gly Pro Pro Ala His Gly Phe Gln Ser 
        275                 280                 285             


Pro Met Gly Ile Lys Gln Glu Pro Arg Asp Tyr Cys Val Asp Ser Glu 
    290                 295                 300                 


Val Pro Asn Cys Gln Ser Ser Tyr Met Arg Gly Gly Tyr Phe Ser Ser 
305                 310                 315                 320 


Ser His Glu Gly Phe Ser Tyr Glu Lys Asp Pro Arg Leu Tyr Phe Asp 
                325                 330                 335     


Asp Thr Cys Val Val Pro Glu Arg Leu Glu Gly Lys Val Lys Gln Glu 
            340                 345                 350         


Pro Thr Met Tyr Arg Glu Gly Pro Pro Tyr Gln Arg Arg Gly Ser Leu 
        355                 360                 365             


Gln Leu Trp Gln Phe Leu Val Thr Leu Leu Asp Asp Pro Ala Asn Ala 
    370                 375                 380                 


His Phe Ile Ala Trp Thr Gly Arg Gly Met Glu Phe Lys Leu Ile Glu 
385                 390                 395                 400 


Pro Glu Glu Val Ala Arg Arg Trp Gly Ile Gln Lys Asn Arg Pro Ala 
                405                 410                 415     


Met Asn Tyr Asp Lys Leu Ser Arg Ser Leu Arg Tyr Tyr Tyr Glu Lys 
            420                 425                 430         


Gly Ile Met Gln Lys Val Ala Gly Glu Arg Tyr Val Tyr Lys Phe Val 
        435                 440                 445             


Cys Asp Pro Asp Ala Leu Phe Ser Met Ala Phe Pro Asp Asn Gln Arg 
    450                 455                 460                 


Pro Phe Leu Lys Ala Glu Ser Glu Cys His Leu Ser Glu Glu Asp Thr 
465                 470                 475                 480 


Leu Pro Leu Thr His Phe Glu Asp Ser Pro Ala Tyr Leu Leu Asp Met 
                485                 490                 495     


Asp Arg Cys Ser Ser Leu Pro Tyr Ala Glu Gly Phe Ala Tyr 
            500                 505                 510 


<210>  3707
<211>  613
<212>  PRT
<213>  homo sapiens

<400>  3707

Met Cys Cys Trp Pro Leu Leu Leu Leu Trp Gly Leu Leu Pro Gly Thr 
1               5                   10                  15      


Ala Ala Gly Gly Ser Gly Arg Thr Tyr Pro His Arg Thr Leu Leu Asp 
            20                  25                  30          


Ser Glu Gly Lys Tyr Trp Leu Gly Trp Ser Gln Arg Gly Ser Gln Ile 
        35                  40                  45              


Ala Phe Arg Leu Gln Val Arg Thr Ala Gly Tyr Val Gly Phe Gly Phe 
    50                  55                  60                  


Ser Pro Thr Gly Ala Met Ala Ser Ala Asp Ile Val Val Gly Gly Val 
65                  70                  75                  80  


Ala His Gly Arg Pro Tyr Leu Gln Asp Tyr Phe Thr Asn Ala Asn Arg 
                85                  90                  95      


Glu Leu Lys Lys Asp Ala Gln Gln Asp Tyr His Leu Glu Tyr Ala Met 
            100                 105                 110         


Glu Asn Ser Thr His Thr Ile Ile Glu Phe Thr Arg Glu Leu His Thr 
        115                 120                 125             


Cys Asp Ile Asn Asp Lys Ser Ile Thr Asp Ser Thr Val Arg Val Ile 
    130                 135                 140                 


Trp Ala Tyr His His Glu Asp Ala Gly Glu Ala Gly Pro Lys Tyr His 
145                 150                 155                 160 


Asp Ser Asn Arg Gly Thr Lys Ser Leu Arg Leu Leu Asn Pro Glu Lys 
                165                 170                 175     


Thr Ser Val Leu Ser Thr Ala Leu Pro Tyr Phe Asp Leu Val Asn Gln 
            180                 185                 190         


Asp Val Pro Ile Pro Asn Lys Asp Thr Thr Tyr Trp Cys Gln Met Phe 
        195                 200                 205             


Lys Ile Pro Val Phe Gln Glu Lys His His Val Ile Lys Val Glu Pro 
    210                 215                 220                 


Val Ile Gln Arg Gly His Glu Ser Leu Val His His Ile Leu Leu Tyr 
225                 230                 235                 240 


Gln Cys Ser Asn Asn Phe Asn Asp Ser Val Leu Glu Ser Gly His Glu 
                245                 250                 255     


Cys Tyr His Pro Asn Met Pro Asp Ala Phe Leu Thr Cys Glu Thr Val 
            260                 265                 270         


Ile Phe Ala Trp Ala Ile Gly Gly Glu Gly Phe Ser Tyr Pro Pro His 
        275                 280                 285             


Val Gly Leu Ser Leu Gly Thr Pro Leu Asp Pro His Tyr Val Leu Leu 
    290                 295                 300                 


Glu Val His Tyr Asp Asn Pro Thr Tyr Glu Glu Gly Leu Ile Asp Asn 
305                 310                 315                 320 


Ser Gly Leu Arg Leu Phe Tyr Thr Met Asp Ile Arg Lys Tyr Asp Ala 
                325                 330                 335     


Gly Val Ile Glu Ala Gly Leu Trp Val Ser Leu Phe His Thr Ile Pro 
            340                 345                 350         


Pro Gly Met Pro Glu Phe Gln Ser Glu Gly His Cys Thr Leu Glu Cys 
        355                 360                 365             


Leu Glu Glu Ala Leu Glu Ala Glu Lys Pro Ser Gly Ile His Val Phe 
    370                 375                 380                 


Ala Val Leu Leu His Ala His Leu Ala Gly Arg Gly Ile Arg Leu Arg 
385                 390                 395                 400 


His Phe Arg Lys Gly Lys Glu Met Lys Leu Leu Ala Tyr Asp Asp Asp 
                405                 410                 415     


Phe Asp Phe Asn Phe Gln Glu Phe Gln Tyr Leu Lys Glu Glu Gln Thr 
            420                 425                 430         


Ile Leu Pro Gly Asp Asn Leu Ile Thr Glu Cys Arg Tyr Asn Thr Lys 
        435                 440                 445             


Asp Arg Ala Glu Met Thr Trp Gly Gly Leu Ser Thr Arg Ser Glu Met 
    450                 455                 460                 


Cys Leu Ser Tyr Leu Leu Tyr Tyr Pro Arg Ile Asn Leu Thr Arg Cys 
465                 470                 475                 480 


Ala Ser Ile Pro Asp Ile Met Glu Gln Leu Gln Phe Ile Gly Val Lys 
                485                 490                 495     


Glu Ile Tyr Arg Pro Val Thr Thr Trp Pro Phe Ile Ile Lys Ser Pro 
            500                 505                 510         


Lys Gln Tyr Lys Asn Leu Ser Phe Met Asp Ala Met Asn Lys Phe Lys 
        515                 520                 525             


Trp Thr Lys Lys Glu Gly Leu Ser Phe Asn Lys Leu Val Leu Ser Leu 
    530                 535                 540                 


Pro Val Asn Val Arg Cys Ser Lys Thr Asp Asn Ala Glu Trp Ser Ile 
545                 550                 555                 560 


Gln Gly Met Thr Ala Leu Pro Pro Asp Ile Glu Arg Pro Tyr Lys Ala 
                565                 570                 575     


Glu Pro Leu Val Cys Gly Thr Ser Ser Ser Ser Ser Leu His Arg Asp 
            580                 585                 590         


Phe Ser Ile Asn Leu Leu Val Cys Leu Leu Leu Leu Ser Cys Thr Leu 
        595                 600                 605             


Ser Thr Lys Ser Leu 
    610             


<210>  3708
<211>  427
<212>  PRT
<213>  homo sapiens

<400>  3708

Met Ala Pro Lys Lys Arg Pro Glu Thr Gln Lys Thr Ser Glu Ile Val 
1               5                   10                  15      


Leu Arg Pro Arg Asn Lys Arg Ser Arg Ser Pro Leu Glu Leu Glu Pro 
            20                  25                  30          


Glu Ala Lys Lys Leu Cys Ala Lys Gly Ser Gly Pro Ser Arg Arg Cys 
        35                  40                  45              


Asp Ser Asp Cys Leu Trp Val Gly Leu Ala Gly Pro Gln Ile Leu Pro 
    50                  55                  60                  


Pro Cys Arg Ser Ile Val Arg Thr Leu His Gln His Lys Leu Gly Arg 
65                  70                  75                  80  


Ala Ser Trp Pro Ser Val Gln Gln Gly Leu Gln Gln Ser Phe Leu His 
                85                  90                  95      


Thr Leu Asp Ser Tyr Arg Ile Leu Gln Lys Ala Ala Pro Phe Asp Arg 
            100                 105                 110         


Arg Ala Thr Ser Leu Ala Trp His Pro Thr His Pro Ser Thr Val Ala 
        115                 120                 125             


Val Gly Ser Lys Gly Gly Asp Ile Met Leu Trp Asn Phe Gly Ile Lys 
    130                 135                 140                 


Asp Lys Pro Thr Phe Ile Lys Gly Ile Gly Ala Gly Gly Ser Ile Thr 
145                 150                 155                 160 


Gly Leu Lys Phe Asn Pro Leu Asn Thr Asn Gln Phe Tyr Ala Ser Ser 
                165                 170                 175     


Met Glu Gly Thr Thr Arg Leu Gln Asp Phe Lys Gly Asn Ile Leu Arg 
            180                 185                 190         


Val Phe Ala Ser Ser Asp Thr Ile Asn Ile Trp Phe Cys Ser Leu Asp 
        195                 200                 205             


Val Ser Ala Ser Ser Arg Met Val Val Thr Gly Asp Asn Val Gly Asn 
    210                 215                 220                 


Val Ile Leu Leu Asn Met Asp Gly Lys Glu Leu Trp Asn Leu Arg Met 
225                 230                 235                 240 


His Lys Lys Lys Val Thr His Val Ala Leu Asn Pro Cys Cys Asp Trp 
                245                 250                 255     


Phe Leu Ala Thr Ala Ser Val Asp Gln Thr Val Lys Ile Trp Asp Leu 
            260                 265                 270         


Arg Gln Val Arg Gly Lys Ala Ser Phe Leu Tyr Ser Leu Pro His Arg 
        275                 280                 285             


His Pro Val Asn Ala Ala Cys Phe Ser Pro Asp Gly Ala Arg Leu Leu 
    290                 295                 300                 


Thr Thr Asp Gln Lys Ser Glu Ile Arg Val Tyr Ser Ala Ser Gln Trp 
305                 310                 315                 320 


Asp Cys Pro Leu Gly Leu Ile Pro His Pro His Arg His Phe Gln His 
                325                 330                 335     


Leu Thr Pro Ile Lys Ala Ala Trp His Pro Arg Tyr Asn Leu Ile Val 
            340                 345                 350         


Val Gly Arg Tyr Pro Asp Pro Asn Phe Lys Ser Cys Thr Pro Tyr Glu 
        355                 360                 365             


Leu Arg Thr Ile Asp Val Phe Asp Gly Asn Ser Gly Lys Met Met Cys 
    370                 375                 380                 


Gln Leu Tyr Asp Pro Glu Ser Ser Gly Ile Ser Ser Leu Asn Glu Phe 
385                 390                 395                 400 


Asn Pro Met Gly Asp Thr Leu Ala Ser Ala Met Gly Tyr His Ile Leu 
                405                 410                 415     


Ile Trp Ser Gln Glu Glu Ala Arg Thr Arg Lys 
            420                 425         


<210>  3709
<211>  731
<212>  PRT
<213>  homo sapiens

<400>  3709

Met Val Val Glu His Pro Glu Phe Leu Lys Ala Gly Lys Glu Pro Gly 
1               5                   10                  15      


Leu Gln Ile Trp Arg Val Glu Lys Phe Asp Leu Val Pro Val Pro Thr 
            20                  25                  30          


Asn Leu Tyr Gly Asp Phe Phe Thr Gly Asp Ala Tyr Val Ile Leu Lys 
        35                  40                  45              


Thr Val Gln Leu Arg Asn Gly Asn Leu Gln Tyr Asp Leu His Tyr Trp 
    50                  55                  60                  


Leu Gly Asn Glu Cys Ser Gln Asp Glu Ser Gly Ala Ala Ala Ile Phe 
65                  70                  75                  80  


Thr Val Gln Leu Asp Asp Tyr Leu Asn Gly Arg Ala Val Gln His Arg 
                85                  90                  95      


Glu Val Gln Gly Phe Glu Ser Ala Thr Phe Leu Gly Tyr Phe Lys Ser 
            100                 105                 110         


Gly Leu Lys Tyr Lys Lys Gly Gly Val Ala Ser Gly Phe Lys His Val 
        115                 120                 125             


Val Pro Asn Glu Val Val Val Gln Arg Leu Phe Gln Val Lys Gly Arg 
    130                 135                 140                 


Arg Val Val Arg Ala Thr Glu Val Pro Val Ser Trp Glu Ser Phe Asn 
145                 150                 155                 160 


Asn Gly Asp Cys Phe Ile Leu Asp Leu Gly Asn Asn Ile His Gln Trp 
                165                 170                 175     


Cys Gly Ser Asn Ser Asn Arg Tyr Glu Arg Leu Lys Ala Thr Gln Val 
            180                 185                 190         


Ser Lys Gly Ile Arg Asp Asn Glu Arg Ser Gly Arg Ala Arg Val His 
        195                 200                 205             


Val Ser Glu Glu Gly Thr Glu Pro Glu Ala Met Leu Gln Val Leu Gly 
    210                 215                 220                 


Pro Lys Pro Ala Leu Pro Ala Gly Thr Glu Asp Thr Ala Lys Glu Asp 
225                 230                 235                 240 


Ala Ala Asn Arg Lys Leu Ala Lys Leu Tyr Lys Val Ser Asn Gly Ala 
                245                 250                 255     


Gly Thr Met Ser Val Ser Leu Val Ala Asp Glu Asn Pro Phe Ala Gln 
            260                 265                 270         


Gly Ala Leu Lys Ser Glu Asp Cys Phe Ile Leu Asp His Gly Lys Asp 
        275                 280                 285             


Gly Lys Ile Phe Val Trp Lys Gly Lys Gln Ala Asn Thr Glu Glu Arg 
    290                 295                 300                 


Lys Ala Ala Leu Lys Thr Ala Ser Asp Phe Ile Thr Lys Met Asp Tyr 
305                 310                 315                 320 


Pro Lys Gln Thr Gln Val Ser Val Leu Pro Glu Gly Gly Glu Thr Pro 
                325                 330                 335     


Leu Phe Lys Gln Phe Phe Lys Asn Trp Arg Asp Pro Asp Gln Thr Asp 
            340                 345                 350         


Gly Leu Gly Leu Ser Tyr Leu Ser Ser His Ile Ala Asn Val Glu Arg 
        355                 360                 365             


Val Pro Phe Asp Ala Ala Thr Leu His Thr Ser Thr Ala Met Ala Ala 
    370                 375                 380                 


Gln His Gly Met Asp Asp Asp Gly Thr Gly Gln Lys Gln Ile Trp Arg 
385                 390                 395                 400 


Ile Glu Gly Ser Asn Lys Val Pro Val Asp Pro Ala Thr Tyr Gly Gln 
                405                 410                 415     


Phe Tyr Gly Gly Asp Ser Tyr Ile Ile Leu Tyr Asn Tyr Arg His Gly 
            420                 425                 430         


Gly Arg Gln Gly Gln Ile Ile Tyr Asn Trp Gln Gly Ala Gln Ser Thr 
        435                 440                 445             


Gln Asp Glu Val Ala Ala Ser Ala Ile Leu Thr Ala Gln Leu Asp Glu 
    450                 455                 460                 


Glu Leu Gly Gly Thr Pro Val Gln Ser Arg Val Val Gln Gly Lys Glu 
465                 470                 475                 480 


Pro Ala His Leu Met Ser Leu Phe Gly Gly Lys Pro Met Ile Ile Tyr 
                485                 490                 495     


Lys Gly Gly Thr Ser Arg Glu Gly Gly Gln Thr Ala Pro Ala Ser Thr 
            500                 505                 510         


Arg Leu Phe Gln Val Arg Ala Asn Ser Ala Gly Ala Thr Arg Ala Val 
        515                 520                 525             


Glu Val Leu Pro Lys Ala Gly Ala Leu Asn Ser Asn Asp Ala Phe Val 
    530                 535                 540                 


Leu Lys Thr Pro Ser Ala Ala Tyr Leu Trp Val Gly Thr Gly Ala Ser 
545                 550                 555                 560 


Glu Ala Glu Lys Thr Gly Ala Gln Glu Leu Leu Arg Val Leu Arg Ala 
                565                 570                 575     


Gln Pro Val Gln Val Ala Glu Gly Ser Glu Pro Asp Gly Phe Trp Glu 
            580                 585                 590         


Ala Leu Gly Gly Lys Ala Ala Tyr Arg Thr Ser Pro Arg Leu Lys Asp 
        595                 600                 605             


Lys Lys Met Asp Ala His Pro Pro Arg Leu Phe Ala Cys Ser Asn Lys 
    610                 615                 620                 


Ile Gly Arg Phe Val Ile Glu Glu Val Pro Gly Glu Leu Met Gln Glu 
625                 630                 635                 640 


Asp Leu Ala Thr Asp Asp Val Met Leu Leu Asp Thr Trp Asp Gln Val 
                645                 650                 655     


Phe Val Trp Val Gly Lys Asp Ser Gln Glu Glu Glu Lys Thr Glu Ala 
            660                 665                 670         


Leu Thr Ser Ala Lys Arg Tyr Ile Glu Thr Asp Pro Ala Asn Arg Asp 
        675                 680                 685             


Arg Arg Thr Pro Ile Thr Val Val Lys Gln Gly Phe Glu Pro Pro Ser 
    690                 695                 700                 


Phe Val Gly Trp Phe Leu Gly Trp Asp Asp Asp Tyr Trp Ser Val Asp 
705                 710                 715                 720 


Pro Leu Asp Arg Ala Met Ala Glu Leu Ala Ala 
                725                 730     


<210>  3710
<211>  716
<212>  PRT
<213>  homo sapiens

<400>  3710

Met Pro Ser Thr Ser Phe Pro Val Pro Ser Lys Phe Pro Leu Gly Pro 
1               5                   10                  15      


Ala Ala Ala Val Phe Gly Arg Gly Glu Thr Leu Gly Pro Ala Pro Arg 
            20                  25                  30          


Ala Gly Gly Thr Met Lys Ser Ala Glu Glu Glu His Tyr Gly Tyr Ala 
        35                  40                  45              


Ser Ser Asn Val Ser Pro Ala Leu Pro Leu Pro Thr Ala His Ser Thr 
    50                  55                  60                  


Leu Pro Ala Pro Cys His Asn Leu Gln Thr Ser Thr Pro Gly Ile Ile 
65                  70                  75                  80  


Pro Pro Ala Asp His Pro Ser Gly Tyr Gly Ala Ala Leu Asp Gly Gly 
                85                  90                  95      


Pro Ala Gly Tyr Phe Leu Ser Ser Gly His Thr Arg Pro Asp Gly Ala 
            100                 105                 110         


Pro Ala Leu Glu Ser Pro Arg Ile Glu Ile Thr Ser Cys Leu Gly Leu 
        115                 120                 125             


Tyr His Asn Asn Asn Gln Phe Phe His Asp Val Glu Val Glu Asp Val 
    130                 135                 140                 


Leu Pro Ser Ser Lys Arg Ser Pro Ser Thr Ala Thr Leu Ser Leu Pro 
145                 150                 155                 160 


Ser Leu Glu Ala Tyr Arg Asp Pro Ser Cys Leu Ser Pro Ala Ser Ser 
                165                 170                 175     


Leu Ser Ser Arg Ser Cys Asn Ser Glu Ala Ser Ser Tyr Glu Ser Asn 
            180                 185                 190         


Tyr Ser Tyr Pro Tyr Ala Ser Pro Gln Thr Ser Pro Trp Gln Ser Pro 
        195                 200                 205             


Cys Val Ser Pro Lys Thr Thr Asp Pro Glu Glu Gly Phe Pro Arg Gly 
    210                 215                 220                 


Leu Gly Ala Cys Thr Leu Leu Gly Ser Pro Arg His Ser Pro Ser Thr 
225                 230                 235                 240 


Ser Pro Arg Ala Ser Val Thr Glu Glu Ser Trp Leu Gly Ala Arg Ser 
                245                 250                 255     


Ser Arg Pro Ala Ser Pro Cys Asn Lys Arg Lys Tyr Ser Leu Asn Gly 
            260                 265                 270         


Arg Gln Pro Pro Tyr Ser Pro His His Ser Pro Thr Pro Ser Pro His 
        275                 280                 285             


Gly Ser Pro Arg Val Ser Val Thr Asp Asp Ser Trp Leu Gly Asn Thr 
    290                 295                 300                 


Thr Gln Tyr Thr Ser Ser Ala Ile Val Ala Ala Ile Asn Ala Leu Thr 
305                 310                 315                 320 


Thr Asp Ser Ser Leu Asp Leu Gly Asp Gly Val Pro Val Lys Ser Arg 
                325                 330                 335     


Lys Thr Thr Leu Glu Gln Pro Pro Ser Val Ala Leu Lys Val Glu Pro 
            340                 345                 350         


Val Gly Glu Asp Leu Gly Ser Pro Pro Pro Pro Ala Asp Phe Ala Pro 
        355                 360                 365             


Glu Asp Tyr Ser Ser Phe Gln His Ile Arg Lys Gly Gly Phe Cys Asp 
    370                 375                 380                 


Gln Tyr Leu Ala Val Pro Gln His Pro Tyr Gln Trp Ala Lys Pro Lys 
385                 390                 395                 400 


Pro Leu Ser Pro Thr Ser Tyr Met Ser Pro Thr Leu Pro Ala Leu Asp 
                405                 410                 415     


Trp Gln Leu Pro Ser His Ser Gly Pro Tyr Glu Leu Arg Ile Glu Val 
            420                 425                 430         


Gln Pro Lys Ser His His Arg Ala His Tyr Glu Thr Glu Gly Ser Arg 
        435                 440                 445             


Gly Ala Val Lys Ala Ser Ala Gly Gly His Pro Ile Val Gln Leu His 
    450                 455                 460                 


Gly Tyr Leu Glu Asn Glu Pro Leu Met Leu Gln Leu Phe Ile Gly Thr 
465                 470                 475                 480 


Ala Asp Asp Arg Leu Leu Arg Pro His Ala Phe Tyr Gln Val His Arg 
                485                 490                 495     


Ile Thr Gly Lys Thr Val Ser Thr Thr Ser His Glu Ala Ile Leu Ser 
            500                 505                 510         


Asn Thr Lys Val Leu Glu Ile Pro Leu Leu Pro Glu Asn Ser Met Arg 
        515                 520                 525             


Ala Val Ile Asp Cys Ala Gly Ile Leu Lys Leu Arg Asn Ser Asp Ile 
    530                 535                 540                 


Glu Leu Arg Lys Gly Glu Thr Asp Ile Gly Arg Lys Asn Thr Arg Val 
545                 550                 555                 560 


Arg Leu Val Phe Arg Val His Val Pro Gln Pro Ser Gly Arg Thr Leu 
                565                 570                 575     


Ser Leu Gln Val Ala Ser Asn Pro Ile Glu Cys Ser Gln Arg Ser Ala 
            580                 585                 590         


Gln Glu Leu Pro Leu Val Glu Lys Gln Ser Thr Asp Ser Tyr Pro Val 
        595                 600                 605             


Val Gly Gly Lys Lys Met Val Leu Ser Gly His Asn Phe Leu Gln Asp 
    610                 615                 620                 


Ser Lys Val Ile Phe Val Glu Lys Ala Pro Asp Gly His His Val Trp 
625                 630                 635                 640 


Glu Met Glu Ala Lys Thr Asp Arg Asp Leu Cys Lys Pro Asn Ser Leu 
                645                 650                 655     


Val Val Glu Ile Pro Pro Phe Arg Asn Gln Arg Ile Thr Ser Pro Val 
            660                 665                 670         


His Val Ser Phe Tyr Val Cys Asn Gly Lys Arg Lys Arg Ser Gln Tyr 
        675                 680                 685             


Gln Arg Phe Thr Tyr Leu Pro Ala Asn Gly Asn Ala Ile Phe Leu Thr 
    690                 695                 700                 


Val Ser Arg Glu His Glu Arg Val Gly Cys Phe Phe 
705                 710                 715     


<210>  3711
<211>  160
<212>  PRT
<213>  homo sapiens

<400>  3711

Met Ser Asp Asn Asp Asp Ile Glu Val Glu Ser Asp Glu Glu Gln Pro 
1               5                   10                  15      


Arg Phe Gln Ser Ala Ala Asp Lys Arg Ala His His Asn Ala Leu Glu 
            20                  25                  30          


Arg Lys Arg Arg Asp His Ile Lys Asp Ser Phe His Ser Leu Arg Asp 
        35                  40                  45              


Ser Val Pro Ser Leu Gln Gly Glu Lys Ala Ser Arg Ala Gln Ile Leu 
    50                  55                  60                  


Asp Lys Ala Thr Glu Tyr Ile Gln Tyr Met Arg Arg Lys Asn His Thr 
65                  70                  75                  80  


His Gln Gln Asp Ile Asp Asp Leu Lys Arg Gln Asn Ala Leu Leu Glu 
                85                  90                  95      


Gln Gln Val Arg Ala Leu Glu Lys Ala Arg Ser Ser Ala Gln Leu Gln 
            100                 105                 110         


Thr Asn Tyr Pro Ser Ser Asp Asn Ser Leu Tyr Thr Asn Ala Lys Gly 
        115                 120                 125             


Ser Thr Ile Ser Ala Phe Asp Gly Gly Ser Asp Ser Ser Ser Glu Ser 
    130                 135                 140                 


Glu Pro Glu Glu Pro Gln Ser Arg Lys Lys Leu Arg Met Glu Ala Ser 
145                 150                 155                 160 


<210>  3712
<211>  440
<212>  PRT
<213>  homo sapiens

<400>  3712

Met Ala Glu Asn Asn Glu Asn Ile Ser Lys Asn Val Asp Val Arg Pro 
1               5                   10                  15      


Lys Thr Ser Arg Ser Arg Ser Ala Asp Arg Lys Asp Gly Tyr Val Trp 
            20                  25                  30          


Ser Gly Lys Lys Leu Ser Trp Ser Lys Lys Ser Glu Ser Tyr Ser Asp 
        35                  40                  45              


Ala Glu Thr Val Asn Gly Ile Glu Lys Thr Glu Val Ser Leu Arg Asn 
    50                  55                  60                  


Gln Glu Arg Lys His Ser Cys Ser Ser Ile Glu Leu Asp Leu Asp His 
65                  70                  75                  80  


Ser Cys Gly His Arg Phe Leu Gly Arg Ser Leu Lys Gln Lys Leu Gln 
                85                  90                  95      


Asp Ala Val Gly Gln Cys Phe Pro Ile Lys Asn Cys Ser Ser Arg His 
            100                 105                 110         


Ser Ser Gly Leu Pro Ser Lys Arg Lys Ile His Ile Ser Glu Leu Met 
        115                 120                 125             


Leu Asp Lys Cys Pro Phe Pro Pro Arg Ser Asp Leu Ala Phe Arg Trp 
    130                 135                 140                 


His Phe Ile Lys Arg His Thr Ala Pro Ile Asn Ser Lys Ser Asp Glu 
145                 150                 155                 160 


Trp Val Ser Thr Asp Leu Ser Gln Thr Glu Leu Arg Asp Gly Gln Leu 
                165                 170                 175     


Lys Arg Arg Asn Met Glu Glu Asn Ile Asn Cys Phe Ser His Thr Asn 
            180                 185                 190         


Val Gln Pro Cys Val Ile Thr Thr Asp Asn Ala Leu Cys Arg Glu Gly 
        195                 200                 205             


Pro Met Thr Gly Ser Val Met Asn Leu Val Ser Asn Asn Ser Ile Glu 
    210                 215                 220                 


Asp Ser Asp Met Asp Ser Asp Asp Glu Ile Leu Thr Leu Cys Thr Ser 
225                 230                 235                 240 


Ser Arg Lys Arg Asn Lys Pro Lys Trp Asp Leu Asp Asp Glu Ile Leu 
                245                 250                 255     


Gln Leu Glu Thr Pro Pro Lys Tyr His Thr Gln Ile Asp Tyr Val His 
            260                 265                 270         


Cys Leu Val Pro Asp Leu Leu Gln Ile Asn Asn Asn Pro Cys Tyr Trp 
        275                 280                 285             


Gly Val Met Asp Lys Tyr Ala Ala Glu Ala Leu Leu Glu Gly Lys Pro 
    290                 295                 300                 


Glu Gly Thr Phe Leu Leu Arg Asp Ser Ala Gln Glu Asp Tyr Leu Phe 
305                 310                 315                 320 


Ser Val Ser Phe Arg Arg Tyr Ser Arg Ser Leu His Ala Arg Ile Glu 
                325                 330                 335     


Gln Trp Asn His Asn Phe Ser Phe Asp Ala His Asp Pro Cys Val Phe 
            340                 345                 350         


His Ser Pro Asp Ile Thr Gly Leu Leu Glu His Tyr Lys Asp Pro Ser 
        355                 360                 365             


Ala Cys Met Phe Phe Glu Pro Leu Leu Ser Thr Pro Leu Ile Arg Thr 
    370                 375                 380                 


Phe Pro Phe Ser Leu Gln His Ile Cys Arg Thr Val Ile Cys Asn Cys 
385                 390                 395                 400 


Thr Thr Tyr Asp Gly Ile Asp Ala Leu Pro Ile Pro Ser Ser Met Lys 
                405                 410                 415     


Leu Tyr Leu Lys Glu Tyr His Tyr Lys Ser Lys Val Arg Val Leu Arg 
            420                 425                 430         


Ile Asp Ala Pro Glu Gln Gln Cys 
        435                 440 


<210>  3713
<211>  1112
<212>  PRT
<213>  homo sapiens

<400>  3713

Met Ala Ala Gly Lys Ser Gly Gly Ser Ala Gly Glu Ile Thr Phe Leu 
1               5                   10                  15      


Glu Ala Leu Ala Arg Ser Glu Ser Lys Arg Asp Gly Gly Phe Lys Asn 
            20                  25                  30          


Asn Trp Ser Phe Asp His Glu Glu Glu Ser Glu Gly Asp Thr Asp Lys 
        35                  40                  45              


Asp Gly Thr Asn Leu Leu Ser Val Asp Glu Asp Glu Asp Ser Glu Thr 
    50                  55                  60                  


Ser Lys Gly Lys Lys Leu Asn Arg Arg Ser Glu Ile Val Ala Asn Ser 
65                  70                  75                  80  


Ser Gly Glu Phe Ile Leu Lys Thr Tyr Val Arg Arg Asn Lys Ser Glu 
                85                  90                  95      


Ser Phe Lys Thr Leu Lys Gly Asn Pro Ile Gly Leu Asn Met Leu Ser 
            100                 105                 110         


Asn Asn Lys Lys Leu Ser Glu Asn Thr Gln Asn Thr Ser Leu Cys Ser 
        115                 120                 125             


Gly Thr Val Val His Gly Arg Arg Phe His His Ala His Ala Gln Ile 
    130                 135                 140                 


Pro Val Val Lys Thr Ala Ala Gln Ser Ser Leu Asp Arg Lys Glu Arg 
145                 150                 155                 160 


Lys Glu Tyr Pro Pro His Val Gln Lys Val Glu Ile Asn Pro Val Arg 
                165                 170                 175     


Leu Ser Arg Leu Gln Gly Val Glu Arg Ile Met Lys Lys Thr Glu Glu 
            180                 185                 190         


Ser Glu Ser Gln Val Glu Pro Glu Ile Lys Arg Lys Val Gln Gln Lys 
        195                 200                 205             


Arg His Cys Ser Thr Tyr Gln Pro Thr Pro Pro Leu Ser Pro Ala Ser 
    210                 215                 220                 


Lys Lys Cys Leu Thr His Leu Glu Asp Leu Gln Arg Asn Cys Arg Gln 
225                 230                 235                 240 


Ala Ile Thr Leu Asn Glu Ser Thr Gly Pro Leu Leu Arg Thr Ser Ile 
                245                 250                 255     


His Gln Asn Ser Gly Gly Gln Lys Ser Gln Asn Thr Gly Leu Thr Thr 
            260                 265                 270         


Lys Lys Phe Tyr Gly Asn Asn Val Glu Lys Val Pro Ile Asp Ile Ile 
        275                 280                 285             


Val Asn Cys Asp Asp Ser Lys His Thr Tyr Leu Gln Thr Asn Gly Lys 
    290                 295                 300                 


Val Ile Leu Pro Gly Ala Lys Ile Pro Lys Ile Thr Asn Leu Lys Glu 
305                 310                 315                 320 


Arg Lys Thr Ser Leu Ser Asp Leu Asn Asp Pro Ile Ile Leu Ser Ser 
                325                 330                 335     


Asp Asp Asp Asp Asp Asn Asp Arg Thr Asn Arg Arg Glu Ser Ile Ser 
            340                 345                 350         


Pro Gln Pro Ala Asp Ser Ala Cys Ser Ser Pro Ala Pro Ser Thr Gly 
        355                 360                 365             


Lys Val Glu Ala Ala Leu Asn Glu Asn Thr Cys Arg Ala Glu Arg Glu 
    370                 375                 380                 


Leu Arg Ser Ile Pro Glu Asp Ser Glu Leu Asn Thr Val Thr Leu Pro 
385                 390                 395                 400 


Arg Lys Ala Arg Met Lys Asp Gln Phe Gly Asn Ser Ile Ile Asn Thr 
                405                 410                 415     


Pro Leu Lys Arg Arg Lys Val Phe Ser Gln Glu Pro Pro Asp Ala Leu 
            420                 425                 430         


Ala Leu Ser Cys Gln Ser Ser Phe Asp Ser Val Ile Leu Asn Cys Arg 
        435                 440                 445             


Ser Ile Arg Val Gly Thr Leu Phe Arg Leu Leu Ile Glu Pro Val Ile 
    450                 455                 460                 


Phe Cys Leu Asp Phe Ile Lys Ile Gln Leu Asp Glu Pro Asp His Asp 
465                 470                 475                 480 


Pro Val Glu Ile Ile Leu Asn Thr Ser Asp Leu Thr Lys Cys Glu Trp 
                485                 490                 495     


Cys Asn Val Arg Lys Leu Pro Val Val Phe Leu Gln Ala Ile Pro Ala 
            500                 505                 510         


Val Tyr Gln Lys Leu Ser Ile Gln Leu Gln Met Asn Lys Glu Asp Lys 
        515                 520                 525             


Val Trp Asn Asp Cys Lys Gly Val Asn Lys Leu Thr Asn Leu Glu Glu 
    530                 535                 540                 


Gln Tyr Ile Ile Leu Ile Phe Gln Asn Gly Leu Asp Pro Pro Ala Asn 
545                 550                 555                 560 


Met Val Phe Glu Ser Ile Ile Asn Glu Ile Gly Ile Lys Asn Asn Ile 
                565                 570                 575     


Ser Asn Phe Phe Ala Lys Ile Pro Phe Glu Glu Ala Asn Gly Arg Leu 
            580                 585                 590         


Val Ala Cys Thr Arg Thr Tyr Glu Glu Ser Ile Lys Gly Ser Cys Gly 
        595                 600                 605             


Gln Lys Glu Asn Lys Ile Lys Thr Val Ser Phe Glu Ser Lys Ile Gln 
    610                 615                 620                 


Leu Arg Ser Lys Gln Glu Phe Gln Phe Phe Asp Glu Glu Glu Glu Thr 
625                 630                 635                 640 


Gly Glu Asn His Thr Ile Phe Ile Gly Pro Val Glu Lys Leu Ile Val 
                645                 650                 655     


Tyr Pro Pro Pro Pro Ala Lys Gly Gly Ile Ser Val Thr Asn Glu Asp 
            660                 665                 670         


Leu His Cys Leu Asn Glu Gly Glu Phe Leu Asn Asp Val Ile Ile Asp 
        675                 680                 685             


Phe Tyr Leu Lys Tyr Leu Val Leu Glu Lys Leu Lys Lys Glu Asp Ala 
    690                 695                 700                 


Asp Arg Ile His Ile Phe Ser Ser Phe Phe Tyr Lys Arg Leu Asn Gln 
705                 710                 715                 720 


Arg Glu Arg Arg Asn His Glu Thr Thr Asn Leu Ser Ile Gln Gln Lys 
                725                 730                 735     


Arg His Gly Arg Val Lys Thr Trp Thr Arg His Val Asp Ile Phe Glu 
            740                 745                 750         


Lys Asp Phe Ile Phe Val Pro Leu Asn Glu Ala Ala His Trp Phe Leu 
        755                 760                 765             


Ala Val Val Cys Phe Pro Gly Leu Glu Lys Pro Lys Tyr Glu Pro Asn 
    770                 775                 780                 


Pro His Tyr His Glu Asn Ala Val Ile Gln Lys Cys Ser Thr Val Glu 
785                 790                 795                 800 


Asp Ser Cys Ile Ser Ser Ser Ala Ser Glu Met Glu Ser Cys Ser Gln 
                805                 810                 815     


Asn Ser Ser Ala Lys Pro Val Ile Lys Lys Met Leu Asn Lys Lys His 
            820                 825                 830         


Cys Ile Ala Val Ile Asp Ser Asn Pro Gly Gln Glu Glu Ser Asp Pro 
        835                 840                 845             


Arg Tyr Lys Arg Asn Ile Cys Ser Val Lys Tyr Ser Val Lys Lys Ile 
    850                 855                 860                 


Asn His Thr Ala Ser Glu Asn Glu Glu Phe Asn Lys Gly Glu Ser Thr 
865                 870                 875                 880 


Ser Gln Lys Val Ala Asp Arg Thr Lys Ser Glu Asn Gly Leu Gln Asn 
                885                 890                 895     


Glu Ser Leu Ser Ser Thr His His Thr Asp Gly Leu Ser Lys Ile Arg 
            900                 905                 910         


Leu Asn Tyr Ser Asp Glu Ser Pro Glu Ala Gly Lys Met Leu Glu Asp 
        915                 920                 925             


Glu Leu Val Asp Phe Ser Glu Asp Gln Asp Asn Gln Asp Asp Ser Ser 
    930                 935                 940                 


Asp Asp Gly Phe Leu Ala Asp Asp Asn Cys Ser Ser Glu Ile Gly Gln 
945                 950                 955                 960 


Trp His Leu Lys Pro Thr Ile Cys Lys Gln Pro Cys Ile Leu Leu Met 
                965                 970                 975     


Asp Ser Leu Arg Gly Pro Ser Arg Ser Asn Val Val Lys Ile Leu Arg 
            980                 985                 990         


Glu Tyr Leu Glu Val Glu Trp Glu  Val Lys Lys Gly Ser  Lys Arg Ser 
        995                 1000                 1005             


Phe Ser  Lys Asp Val Met Lys  Gly Ser Asn Pro Lys  Val Pro Gln 
    1010                 1015                 1020             


Gln Asn  Asn Phe Ser Asp Cys  Gly Val Tyr Val Leu  Gln Tyr Val 
    1025                 1030                 1035             


Glu Ser  Phe Phe Glu Asn Pro  Ile Leu Ser Phe Glu  Leu Pro Met 
    1040                 1045                 1050             


Asn Leu  Ala Asn Trp Phe Pro  Pro Pro Arg Met Arg  Thr Lys Arg 
    1055                 1060                 1065             


Glu Glu  Ile Arg Asn Ile Ile  Leu Lys Leu Gln Glu  Asp Gln Ser 
    1070                 1075                 1080             


Lys Glu  Lys Arg Lys His Lys  Asp Thr Tyr Ser Thr  Glu Ala Pro 
    1085                 1090                 1095             


Leu Gly  Glu Gly Thr Glu Gln  Tyr Val Asn Ser Ile  Ser Asp 
    1100                 1105                 1110         


<210>  3714
<211>  1105
<212>  PRT
<213>  homo sapiens

<400>  3714

Met Ala Ala Gly Lys Ser Gly Gly Ser Ala Gly Glu Ile Thr Phe Leu 
1               5                   10                  15      


Glu Ala Leu Ala Arg Ser Glu Ser Lys Arg Asp Gly Gly Phe Lys Asn 
            20                  25                  30          


Asn Trp Ser Phe Asp His Glu Glu Glu Ser Glu Gly Asp Thr Asp Lys 
        35                  40                  45              


Asp Gly Thr Asn Leu Leu Ser Val Asp Glu Asp Glu Asp Ser Glu Thr 
    50                  55                  60                  


Ser Lys Gly Lys Lys Leu Asn Arg Arg Ser Glu Ile Val Ala Asn Ser 
65                  70                  75                  80  


Ser Gly Glu Phe Ile Leu Lys Thr Tyr Val Arg Arg Asn Lys Ser Glu 
                85                  90                  95      


Ser Phe Lys Thr Leu Lys Gly Asn Pro Ile Gly Leu Asn Met Leu Ser 
            100                 105                 110         


Asn Asn Lys Lys Leu Ser Glu Asn Thr Gln Asn Thr Ser Leu Cys Ser 
        115                 120                 125             


Gly Thr Val Val His Gly Arg Arg Phe His His Ala His Ala Gln Ile 
    130                 135                 140                 


Pro Val Val Lys Thr Ala Ala Gln Arg Lys Glu Tyr Pro Pro His Val 
145                 150                 155                 160 


Gln Lys Val Glu Ile Asn Pro Val Arg Leu Ser Arg Leu Gln Gly Val 
                165                 170                 175     


Glu Arg Ile Met Lys Lys Thr Glu Glu Ser Glu Ser Gln Val Glu Pro 
            180                 185                 190         


Glu Ile Lys Arg Lys Val Gln Gln Lys Arg His Cys Ser Thr Tyr Gln 
        195                 200                 205             


Pro Thr Pro Pro Leu Ser Pro Ala Ser Lys Lys Cys Leu Thr His Leu 
    210                 215                 220                 


Glu Asp Leu Gln Arg Asn Cys Arg Gln Ala Ile Thr Leu Asn Glu Ser 
225                 230                 235                 240 


Thr Gly Pro Leu Leu Arg Thr Ser Ile His Gln Asn Ser Gly Gly Gln 
                245                 250                 255     


Lys Ser Gln Asn Thr Gly Leu Thr Thr Lys Lys Phe Tyr Gly Asn Asn 
            260                 265                 270         


Val Glu Lys Val Pro Ile Asp Ile Ile Val Asn Cys Asp Asp Ser Lys 
        275                 280                 285             


His Thr Tyr Leu Gln Thr Asn Gly Lys Val Ile Leu Pro Gly Ala Lys 
    290                 295                 300                 


Ile Pro Lys Ile Thr Asn Leu Lys Glu Arg Lys Thr Ser Leu Ser Asp 
305                 310                 315                 320 


Leu Asn Asp Pro Ile Ile Leu Ser Ser Asp Asp Asp Asp Asp Asn Asp 
                325                 330                 335     


Arg Thr Asn Arg Arg Glu Ser Ile Ser Pro Gln Pro Ala Asp Ser Ala 
            340                 345                 350         


Cys Ser Ser Pro Ala Pro Ser Thr Gly Lys Val Glu Ala Ala Leu Asn 
        355                 360                 365             


Glu Asn Thr Cys Arg Ala Glu Arg Glu Leu Arg Ser Ile Pro Glu Asp 
    370                 375                 380                 


Ser Glu Leu Asn Thr Val Thr Leu Pro Arg Lys Ala Arg Met Lys Asp 
385                 390                 395                 400 


Gln Phe Gly Asn Ser Ile Ile Asn Thr Pro Leu Lys Arg Arg Lys Val 
                405                 410                 415     


Phe Ser Gln Glu Pro Pro Asp Ala Leu Ala Leu Ser Cys Gln Ser Ser 
            420                 425                 430         


Phe Asp Ser Val Ile Leu Asn Cys Arg Ser Ile Arg Val Gly Thr Leu 
        435                 440                 445             


Phe Arg Leu Leu Ile Glu Pro Val Ile Phe Cys Leu Asp Phe Ile Lys 
    450                 455                 460                 


Ile Gln Leu Asp Glu Pro Asp His Asp Pro Val Glu Ile Ile Leu Asn 
465                 470                 475                 480 


Thr Ser Asp Leu Thr Lys Cys Glu Trp Cys Asn Val Arg Lys Leu Pro 
                485                 490                 495     


Val Val Phe Leu Gln Ala Ile Pro Ala Val Tyr Gln Lys Leu Ser Ile 
            500                 505                 510         


Gln Leu Gln Met Asn Lys Glu Asp Lys Val Trp Asn Asp Cys Lys Gly 
        515                 520                 525             


Val Asn Lys Leu Thr Asn Leu Glu Glu Gln Tyr Ile Ile Leu Ile Phe 
    530                 535                 540                 


Gln Asn Gly Leu Asp Pro Pro Ala Asn Met Val Phe Glu Ser Ile Ile 
545                 550                 555                 560 


Asn Glu Ile Gly Ile Lys Asn Asn Ile Ser Asn Phe Phe Ala Lys Ile 
                565                 570                 575     


Pro Phe Glu Glu Ala Asn Gly Arg Leu Val Ala Cys Thr Arg Thr Tyr 
            580                 585                 590         


Glu Glu Ser Ile Lys Gly Ser Cys Gly Gln Lys Glu Asn Lys Ile Lys 
        595                 600                 605             


Thr Val Ser Phe Glu Ser Lys Ile Gln Leu Arg Ser Lys Gln Glu Phe 
    610                 615                 620                 


Gln Phe Phe Asp Glu Glu Glu Glu Thr Gly Glu Asn His Thr Ile Phe 
625                 630                 635                 640 


Ile Gly Pro Val Glu Lys Leu Ile Val Tyr Pro Pro Pro Pro Ala Lys 
                645                 650                 655     


Gly Gly Ile Ser Val Thr Asn Glu Asp Leu His Cys Leu Asn Glu Gly 
            660                 665                 670         


Glu Phe Leu Asn Asp Val Ile Ile Asp Phe Tyr Leu Lys Tyr Leu Val 
        675                 680                 685             


Leu Glu Lys Leu Lys Lys Glu Asp Ala Asp Arg Ile His Ile Phe Ser 
    690                 695                 700                 


Ser Phe Phe Tyr Lys Arg Leu Asn Gln Arg Glu Arg Arg Asn His Glu 
705                 710                 715                 720 


Thr Thr Asn Leu Ser Ile Gln Gln Lys Arg His Gly Arg Val Lys Thr 
                725                 730                 735     


Trp Thr Arg His Val Asp Ile Phe Glu Lys Asp Phe Ile Phe Val Pro 
            740                 745                 750         


Leu Asn Glu Ala Ala His Trp Phe Leu Ala Val Val Cys Phe Pro Gly 
        755                 760                 765             


Leu Glu Lys Pro Lys Tyr Glu Pro Asn Pro His Tyr His Glu Asn Ala 
    770                 775                 780                 


Val Ile Gln Lys Cys Ser Thr Val Glu Asp Ser Cys Ile Ser Ser Ser 
785                 790                 795                 800 


Ala Ser Glu Met Glu Ser Cys Ser Gln Asn Ser Ser Ala Lys Pro Val 
                805                 810                 815     


Ile Lys Lys Met Leu Asn Lys Lys His Cys Ile Ala Val Ile Asp Ser 
            820                 825                 830         


Asn Pro Gly Gln Glu Glu Ser Asp Pro Arg Tyr Lys Arg Asn Ile Cys 
        835                 840                 845             


Ser Val Lys Tyr Ser Val Lys Lys Ile Asn His Thr Ala Ser Glu Asn 
    850                 855                 860                 


Glu Glu Phe Asn Lys Gly Glu Ser Thr Ser Gln Lys Val Ala Asp Arg 
865                 870                 875                 880 


Thr Lys Ser Glu Asn Gly Leu Gln Asn Glu Ser Leu Ser Ser Thr His 
                885                 890                 895     


His Thr Asp Gly Leu Ser Lys Ile Arg Leu Asn Tyr Ser Asp Glu Ser 
            900                 905                 910         


Pro Glu Ala Gly Lys Met Leu Glu Asp Glu Leu Val Asp Phe Ser Glu 
        915                 920                 925             


Asp Gln Asp Asn Gln Asp Asp Ser Ser Asp Asp Gly Phe Leu Ala Asp 
    930                 935                 940                 


Asp Asn Cys Ser Ser Glu Ile Gly Gln Trp His Leu Lys Pro Thr Ile 
945                 950                 955                 960 


Cys Lys Gln Pro Cys Ile Leu Leu Met Asp Ser Leu Arg Gly Pro Ser 
                965                 970                 975     


Arg Ser Asn Val Val Lys Ile Leu Arg Glu Tyr Leu Glu Val Glu Trp 
            980                 985                 990         


Glu Val Lys Lys Gly Ser Lys Arg  Ser Phe Ser Lys Asp  Val Met Lys 
        995                 1000                 1005             


Gly Ser  Asn Pro Lys Val Pro  Gln Gln Asn Asn Phe  Ser Asp Cys 
    1010                 1015                 1020             


Gly Val  Tyr Val Leu Gln Tyr  Val Glu Ser Phe Phe  Glu Asn Pro 
    1025                 1030                 1035             


Ile Leu  Ser Phe Glu Leu Pro  Met Asn Leu Ala Asn  Trp Phe Pro 
    1040                 1045                 1050             


Pro Pro  Arg Met Arg Thr Lys  Arg Glu Glu Ile Arg  Asn Ile Ile 
    1055                 1060                 1065             


Leu Lys  Leu Gln Glu Asp Gln  Ser Lys Glu Lys Arg  Lys His Lys 
    1070                 1075                 1080             


Asp Thr  Tyr Ser Thr Glu Ala  Pro Leu Gly Glu Gly  Thr Glu Gln 
    1085                 1090                 1095             


Tyr Val  Asn Ser Ile Ser Asp  
    1100                 1105 


<210>  3715
<211>  12
<212>  PRT
<213>  homo sapiens

<400>  3715

Met Ala Leu Ala Val Arg Val Val Tyr Cys Gly Ala 
1               5                   10          


<210>  3716
<211>  756
<212>  PRT
<213>  homo sapiens

<400>  3716

Met Leu Gly Ile Cys Arg Gly Arg Arg Lys Phe Leu Ala Ala Ser Leu 
1               5                   10                  15      


Ser Leu Leu Cys Ile Pro Ala Ile Thr Trp Ile Tyr Leu Phe Ser Gly 
            20                  25                  30          


Ser Phe Glu Asp Gly Lys Pro Val Ser Leu Ser Pro Leu Glu Ser Gln 
        35                  40                  45              


Ala His Ser Pro Arg Tyr Thr Ala Ser Ser Gln Arg Glu Arg Glu Ser 
    50                  55                  60                  


Leu Glu Val Arg Met Arg Glu Val Glu Glu Glu Asn Arg Ala Leu Arg 
65                  70                  75                  80  


Arg Gln Leu Ser Leu Ala Gln Gly Arg Ala Pro Ser His Arg Arg Gly 
                85                  90                  95      


Asn His Ser Lys Thr Tyr Ser Met Glu Glu Gly Thr Gly Asp Ser Glu 
            100                 105                 110         


Asn Leu Arg Ala Gly Ile Val Ala Gly Asn Ser Ser Glu Cys Gly Gln 
        115                 120                 125             


Gln Pro Val Val Glu Lys Cys Glu Thr Ile His Val Ala Ile Val Cys 
    130                 135                 140                 


Ala Gly Tyr Asn Ala Ser Arg Asp Val Val Thr Leu Val Lys Ser Val 
145                 150                 155                 160 


Leu Phe His Arg Arg Asn Pro Leu His Phe His Leu Ile Ala Asp Ser 
                165                 170                 175     


Ile Ala Glu Gln Ile Leu Ala Thr Leu Phe Gln Thr Trp Met Val Pro 
            180                 185                 190         


Ala Val Arg Val Asp Phe Tyr Asn Ala Asp Glu Leu Lys Ser Glu Val 
        195                 200                 205             


Ser Trp Ile Pro Asn Lys His Tyr Ser Gly Ile Tyr Gly Leu Met Lys 
    210                 215                 220                 


Leu Val Leu Thr Lys Thr Leu Pro Ala Asn Leu Glu Arg Val Ile Val 
225                 230                 235                 240 


Leu Asp Thr Asp Ile Thr Phe Ala Thr Asp Ile Ala Glu Leu Trp Ala 
                245                 250                 255     


Val Phe His Lys Phe Lys Gly Gln Gln Val Leu Gly Leu Val Glu Asn 
            260                 265                 270         


Gln Ser Asp Trp Tyr Leu Gly Asn Leu Trp Lys Asn His Arg Pro Trp 
        275                 280                 285             


Pro Ala Leu Gly Arg Gly Tyr Asn Thr Gly Val Ile Leu Leu Leu Leu 
    290                 295                 300                 


Asp Lys Leu Arg Lys Met Lys Trp Glu Gln Met Trp Arg Leu Thr Ala 
305                 310                 315                 320 


Glu Arg Glu Leu Met Gly Met Leu Ser Thr Ser Leu Ala Asp Gln Asp 
                325                 330                 335     


Ile Phe Asn Ala Val Ile Lys Gln Asn Pro Phe Leu Val Tyr Gln Leu 
            340                 345                 350         


Pro Cys Phe Trp Asn Val Gln Leu Ser Asp His Thr Arg Ser Glu Gln 
        355                 360                 365             


Cys Tyr Arg Asp Val Ser Asp Leu Lys Val Ile His Trp Asn Ser Pro 
    370                 375                 380                 


Lys Lys Leu Arg Val Lys Asn Lys His Val Glu Phe Phe Arg Asn Leu 
385                 390                 395                 400 


Tyr Leu Thr Phe Leu Glu Tyr Asp Gly Asn Leu Leu Arg Arg Glu Leu 
                405                 410                 415     


Phe Gly Cys Pro Ser Glu Ala Asp Val Asn Ser Glu Asn Leu Gln Lys 
            420                 425                 430         


Gln Leu Ser Glu Leu Asp Glu Asp Asp Leu Cys Tyr Glu Phe Arg Arg 
        435                 440                 445             


Glu Arg Phe Thr Val His Arg Thr His Leu Tyr Phe Leu His Tyr Glu 
    450                 455                 460                 


Tyr Glu Pro Ala Ala Asp Ser Thr Asp Val Thr Leu Val Ala Gln Leu 
465                 470                 475                 480 


Ser Met Asp Arg Leu Gln Met Leu Glu Ala Ile Cys Lys His Trp Glu 
                485                 490                 495     


Gly Pro Ile Ser Leu Ala Leu Tyr Leu Ser Asp Ala Glu Ala Gln Gln 
            500                 505                 510         


Phe Leu Arg Tyr Ala Gln Gly Ser Glu Val Leu Met Ser Arg His Asn 
        515                 520                 525             


Val Gly Tyr His Ile Val Tyr Lys Glu Gly Gln Phe Tyr Pro Val Asn 
    530                 535                 540                 


Leu Leu Arg Asn Val Ala Met Lys His Ile Ser Thr Pro Tyr Met Phe 
545                 550                 555                 560 


Leu Ser Asp Ile Asp Phe Leu Pro Met Tyr Gly Leu Tyr Glu Tyr Leu 
                565                 570                 575     


Arg Lys Ser Val Ile Gln Leu Asp Leu Ala Asn Thr Lys Lys Ala Met 
            580                 585                 590         


Ile Val Pro Ala Phe Glu Thr Leu Arg Tyr Arg Leu Ser Phe Pro Lys 
        595                 600                 605             


Ser Lys Ala Glu Leu Leu Ser Met Leu Asp Met Gly Thr Leu Phe Thr 
    610                 615                 620                 


Phe Arg Tyr His Val Trp Thr Lys Gly His Ala Pro Thr Asn Phe Ala 
625                 630                 635                 640 


Lys Trp Arg Thr Ala Thr Thr Pro Tyr Arg Val Glu Trp Glu Ala Asp 
                645                 650                 655     


Phe Glu Pro Tyr Val Val Val Arg Arg Asp Cys Pro Glu Tyr Asp Arg 
            660                 665                 670         


Arg Phe Val Gly Phe Gly Trp Asn Lys Val Ala His Ile Met Glu Leu 
        675                 680                 685             


Asp Val Gln Glu Tyr Glu Phe Ile Val Leu Pro Asn Ala Tyr Met Ile 
    690                 695                 700                 


His Met Pro His Ala Pro Ser Phe Asp Ile Thr Lys Phe Arg Ser Asn 
705                 710                 715                 720 


Lys Gln Tyr Arg Ile Cys Leu Lys Thr Leu Lys Glu Glu Phe Gln Gln 
                725                 730                 735     


Asp Met Ser Arg Arg Tyr Gly Phe Ala Ala Leu Lys Tyr Leu Thr Ala 
            740                 745                 750         


Glu Asn Asn Ser 
        755     


<210>  3717
<211>  407
<212>  PRT
<213>  homo sapiens

<400>  3717

Met Thr Thr Leu Ala Gly Ala Val Pro Arg Met Met Arg Pro Gly Pro 
1               5                   10                  15      


Gly Gln Asn Tyr Pro Arg Ser Gly Phe Pro Leu Glu Val Ser Thr Pro 
            20                  25                  30          


Leu Gly Gln Gly Arg Val Asn Gln Leu Gly Gly Val Phe Ile Asn Gly 
        35                  40                  45              


Arg Pro Leu Pro Asn His Ile Arg His Lys Ile Val Glu Met Ala His 
    50                  55                  60                  


His Gly Ile Arg Pro Cys Val Ile Ser Arg Gln Leu Arg Val Ser His 
65                  70                  75                  80  


Gly Cys Val Ser Lys Ile Leu Cys Arg Tyr Gln Glu Thr Gly Ser Ile 
                85                  90                  95      


Arg Pro Gly Ala Ile Gly Gly Ser Lys Pro Lys Gln Val Thr Thr Pro 
            100                 105                 110         


Asp Val Glu Lys Lys Ile Glu Glu Tyr Lys Arg Glu Asn Pro Gly Met 
        115                 120                 125             


Phe Ser Trp Glu Ile Arg Asp Lys Leu Leu Lys Asp Ala Val Cys Asp 
    130                 135                 140                 


Arg Asn Thr Val Pro Ser Val Ser Ser Ile Ser Arg Ile Leu Arg Ser 
145                 150                 155                 160 


Lys Phe Gly Lys Gly Glu Glu Glu Glu Ala Asp Leu Glu Arg Lys Glu 
                165                 170                 175     


Ala Glu Glu Ser Glu Lys Lys Ala Lys His Ser Ile Asp Gly Ile Leu 
            180                 185                 190         


Ser Glu Arg Ala Ser Ala Pro Gln Ser Asp Glu Gly Ser Asp Ile Asp 
        195                 200                 205             


Ser Glu Pro Asp Leu Pro Leu Lys Arg Lys Gln Arg Arg Ser Arg Thr 
    210                 215                 220                 


Thr Phe Thr Ala Glu Gln Leu Glu Glu Leu Glu Arg Ala Phe Glu Arg 
225                 230                 235                 240 


Thr His Tyr Pro Asp Ile Tyr Thr Arg Glu Glu Leu Ala Gln Arg Ala 
                245                 250                 255     


Lys Leu Thr Glu Ala Arg Val Gln Val Trp Phe Ser Asn Arg Arg Ala 
            260                 265                 270         


Arg Trp Arg Lys Gln Ala Gly Ala Asn Gln Leu Met Ala Phe Asn His 
        275                 280                 285             


Leu Ile Pro Gly Gly Phe Pro Pro Thr Ala Met Pro Thr Leu Pro Thr 
    290                 295                 300                 


Tyr Gln Leu Ser Glu Thr Ser Tyr Gln Pro Thr Ser Ile Pro Gln Ala 
305                 310                 315                 320 


Val Ser Asp Pro Ser Ser Thr Val His Arg Pro Gln Pro Leu Pro Pro 
                325                 330                 335     


Ser Thr Val His Gln Ser Thr Ile Pro Ser Asn Pro Asp Ser Ser Ser 
            340                 345                 350         


Ala Tyr Cys Leu Pro Ser Thr Arg His Gly Phe Ser Ser Tyr Thr Asp 
        355                 360                 365             


Ser Phe Val Pro Pro Ser Gly Pro Ser Asn Pro Met Asn Pro Thr Ile 
    370                 375                 380                 


Gly Asn Gly Leu Ser Pro Gln Val Pro Phe Ile Ile Ser Ser Gln Ile 
385                 390                 395                 400 


Ser Leu Gly Phe Lys Ser Phe 
                405         


<210>  3718
<211>  707
<212>  PRT
<213>  homo sapiens

<400>  3718

Met Gly Gln Thr Gly Lys Lys Ser Glu Lys Gly Pro Val Cys Trp Arg 
1               5                   10                  15      


Lys Arg Val Lys Ser Glu Tyr Met Arg Leu Arg Gln Leu Lys Arg Phe 
            20                  25                  30          


Arg Arg Ala Asp Glu Val Lys Ser Met Phe Ser Ser Asn Arg Gln Lys 
        35                  40                  45              


Ile Leu Glu Arg Thr Glu Ile Leu Asn Gln Glu Trp Lys Gln Arg Arg 
    50                  55                  60                  


Ile Gln Pro Val His Ile Leu Thr Ser Val Ser Ser Leu Arg Gly Thr 
65                  70                  75                  80  


Arg Glu Val Glu Asp Glu Thr Val Leu His Asn Ile Pro Tyr Met Gly 
                85                  90                  95      


Asp Glu Val Leu Asp Gln Asp Gly Thr Phe Ile Glu Glu Leu Ile Lys 
            100                 105                 110         


Asn Tyr Asp Gly Lys Val His Gly Asp Arg Glu Cys Gly Phe Ile Asn 
        115                 120                 125             


Asp Glu Ile Phe Val Glu Leu Val Asn Ala Leu Gly Gln Tyr Asn Asp 
    130                 135                 140                 


Asp Asp Asp Asp Asp Asp Gly Asp Asp Pro Glu Glu Arg Glu Glu Lys 
145                 150                 155                 160 


Gln Lys Asp Leu Glu Asp His Arg Asp Asp Lys Glu Ser Arg Pro Pro 
                165                 170                 175     


Arg Lys Phe Pro Ser Asp Lys Ile Phe Glu Ala Ile Ser Ser Met Phe 
            180                 185                 190         


Pro Asp Lys Gly Thr Ala Glu Glu Leu Lys Glu Lys Tyr Lys Glu Leu 
        195                 200                 205             


Thr Glu Gln Gln Leu Pro Gly Ala Leu Pro Pro Glu Cys Thr Pro Asn 
    210                 215                 220                 


Ile Asp Gly Pro Asn Ala Lys Ser Val Gln Arg Glu Gln Ser Leu His 
225                 230                 235                 240 


Ser Phe His Thr Leu Phe Cys Arg Arg Cys Phe Lys Tyr Asp Cys Phe 
                245                 250                 255     


Leu His Pro Phe His Ala Thr Pro Asn Thr Tyr Lys Arg Lys Asn Thr 
            260                 265                 270         


Glu Thr Ala Leu Asp Asn Lys Pro Cys Gly Pro Gln Cys Tyr Gln His 
        275                 280                 285             


Leu Glu Gly Ala Lys Glu Phe Ala Ala Ala Leu Thr Ala Glu Arg Ile 
    290                 295                 300                 


Lys Thr Pro Pro Lys Arg Pro Gly Gly Arg Arg Arg Gly Arg Leu Pro 
305                 310                 315                 320 


Asn Asn Ser Ser Arg Pro Ser Thr Pro Thr Ile Asn Val Leu Glu Ser 
                325                 330                 335     


Lys Asp Thr Asp Ser Asp Arg Glu Ala Gly Thr Glu Thr Gly Gly Glu 
            340                 345                 350         


Asn Asn Asp Lys Glu Glu Glu Glu Lys Lys Asp Glu Thr Ser Ser Ser 
        355                 360                 365             


Ser Glu Ala Asn Ser Arg Cys Gln Thr Pro Ile Lys Met Lys Pro Asn 
    370                 375                 380                 


Ile Glu Pro Pro Glu Asn Val Glu Trp Ser Gly Ala Glu Ala Ser Met 
385                 390                 395                 400 


Phe Arg Val Leu Ile Gly Thr Tyr Tyr Asp Asn Phe Cys Ala Ile Ala 
                405                 410                 415     


Arg Leu Ile Gly Thr Lys Thr Cys Arg Gln Val Tyr Glu Phe Arg Val 
            420                 425                 430         


Lys Glu Ser Ser Ile Ile Ala Pro Ala Pro Ala Glu Asp Val Asp Thr 
        435                 440                 445             


Pro Pro Arg Lys Lys Lys Arg Lys His Arg Leu Trp Ala Ala His Cys 
    450                 455                 460                 


Arg Lys Ile Gln Leu Lys Lys Asp Gly Ser Ser Asn His Val Tyr Asn 
465                 470                 475                 480 


Tyr Gln Pro Cys Asp His Pro Arg Gln Pro Cys Asp Ser Ser Cys Pro 
                485                 490                 495     


Cys Val Ile Ala Gln Asn Phe Cys Glu Lys Phe Cys Gln Cys Ser Ser 
            500                 505                 510         


Glu Cys Gln Asn Arg Phe Pro Gly Cys Arg Cys Lys Ala Gln Cys Asn 
        515                 520                 525             


Thr Lys Gln Cys Pro Cys Tyr Leu Ala Val Arg Glu Cys Asp Pro Asp 
    530                 535                 540                 


Leu Cys Leu Thr Cys Gly Ala Ala Asp His Trp Asp Ser Lys Asn Val 
545                 550                 555                 560 


Ser Cys Lys Asn Cys Ser Ile Gln Arg Gly Ser Lys Lys His Leu Leu 
                565                 570                 575     


Leu Ala Pro Ser Asp Val Ala Gly Trp Gly Ile Phe Ile Lys Asp Pro 
            580                 585                 590         


Val Gln Lys Asn Glu Phe Ile Ser Glu Tyr Cys Gly Glu Ile Ile Ser 
        595                 600                 605             


Gln Asp Glu Ala Asp Arg Arg Gly Lys Val Tyr Asp Lys Tyr Met Cys 
    610                 615                 620                 


Ser Phe Leu Phe Asn Leu Asn Asn Asp Phe Val Val Asp Ala Thr Arg 
625                 630                 635                 640 


Lys Gly Asn Lys Ile Arg Phe Ala Asn His Ser Val Asn Pro Asn Cys 
                645                 650                 655     


Tyr Ala Lys Val Met Met Val Asn Gly Asp His Arg Ile Gly Ile Phe 
            660                 665                 670         


Ala Lys Arg Ala Ile Gln Thr Gly Glu Glu Leu Phe Phe Asp Tyr Arg 
        675                 680                 685             


Tyr Ser Gln Ala Asp Ala Leu Lys Tyr Val Gly Ile Glu Arg Glu Met 
    690                 695                 700                 


Glu Ile Pro 
705         


<210>  3719
<211>  1863
<212>  PRT
<213>  homo sapiens

<400>  3719

Met Gly Asp Val Lys Leu Val Ala Ser Ser His Ile Ser Lys Thr Ser 
1               5                   10                  15      


Leu Ser Val Asp Pro Ser Arg Val Asp Ser Met Pro Leu Thr Glu Ala 
            20                  25                  30          


Pro Ala Phe Ile Leu Pro Pro Arg Asn Leu Cys Ile Lys Glu Gly Ala 
        35                  40                  45              


Thr Ala Lys Phe Glu Gly Arg Val Arg Gly Tyr Pro Glu Pro Gln Val 
    50                  55                  60                  


Thr Trp His Arg Asn Gly Gln Pro Ile Thr Ser Gly Gly Arg Phe Leu 
65                  70                  75                  80  


Leu Asp Cys Gly Ile Arg Gly Thr Phe Ser Leu Val Ile His Ala Val 
                85                  90                  95      


His Glu Glu Asp Arg Gly Lys Tyr Thr Cys Glu Ala Thr Asn Gly Ser 
            100                 105                 110         


Gly Ala Arg Gln Val Thr Val Glu Leu Thr Val Glu Gly Ser Phe Ala 
        115                 120                 125             


Lys Gln Leu Gly Gln Pro Val Val Ser Lys Thr Leu Gly Asp Arg Phe 
    130                 135                 140                 


Ser Ala Pro Ala Val Glu Thr Arg Pro Ser Ile Trp Gly Glu Cys Pro 
145                 150                 155                 160 


Pro Lys Phe Ala Thr Lys Leu Gly Arg Val Val Val Lys Glu Gly Gln 
                165                 170                 175     


Met Gly Arg Phe Ser Cys Lys Ile Thr Gly Arg Pro Gln Pro Gln Val 
            180                 185                 190         


Thr Trp Leu Lys Gly Asn Val Pro Leu Gln Pro Ser Ala Arg Val Ser 
        195                 200                 205             


Val Ser Glu Lys Asn Gly Met Gln Val Leu Glu Ile His Gly Val Asn 
    210                 215                 220                 


Gln Asp Asp Val Gly Val Tyr Thr Cys Leu Val Val Asn Gly Ser Gly 
225                 230                 235                 240 


Lys Ala Ser Met Ser Ala Glu Leu Ser Ile Gln Gly Leu Asp Ser Ala 
                245                 250                 255     


Asn Arg Ser Phe Val Arg Glu Thr Lys Ala Thr Asn Ser Asp Val Arg 
            260                 265                 270         


Lys Glu Val Thr Asn Val Ile Ser Lys Glu Ser Lys Leu Asp Ser Leu 
        275                 280                 285             


Glu Ala Ala Ala Lys Ser Lys Asn Cys Ser Ser Pro Gln Arg Gly Gly 
    290                 295                 300                 


Ser Pro Pro Trp Ala Ala Asn Ser Gln Pro Gln Pro Pro Arg Glu Ser 
305                 310                 315                 320 


Lys Leu Glu Ser Cys Lys Asp Ser Pro Arg Thr Ala Pro Gln Thr Pro 
                325                 330                 335     


Val Leu Gln Lys Thr Ser Ser Ser Ile Thr Leu Gln Ala Ala Arg Val 
            340                 345                 350         


Gln Pro Glu Pro Arg Ala Pro Gly Leu Gly Val Leu Ser Pro Ser Gly 
        355                 360                 365             


Glu Glu Arg Lys Arg Pro Ala Pro Pro Arg Pro Ala Thr Phe Pro Thr 
    370                 375                 380                 


Arg Gln Pro Gly Leu Gly Ser Gln Asp Val Val Ser Lys Ala Ala Asn 
385                 390                 395                 400 


Arg Arg Ile Pro Met Glu Gly Gln Arg Asp Ser Ala Phe Pro Lys Phe 
                405                 410                 415     


Glu Ser Lys Pro Gln Ser Gln Glu Val Lys Glu Asn Gln Thr Val Lys 
            420                 425                 430         


Phe Arg Cys Glu Val Ser Gly Ile Pro Lys Pro Glu Val Ala Trp Phe 
        435                 440                 445             


Leu Glu Gly Thr Pro Val Arg Arg Gln Glu Gly Ser Ile Glu Val Tyr 
    450                 455                 460                 


Glu Asp Ala Gly Ser His Tyr Leu Cys Leu Leu Lys Ala Arg Thr Arg 
465                 470                 475                 480 


Asp Ser Gly Thr Tyr Ser Cys Thr Ala Ser Asn Ala Gln Gly Gln Leu 
                485                 490                 495     


Ser Cys Ser Trp Thr Leu Gln Val Glu Arg Leu Ala Val Met Glu Val 
            500                 505                 510         


Ala Pro Ser Phe Ser Ser Val Leu Lys Asp Cys Ala Val Ile Glu Gly 
        515                 520                 525             


Gln Asp Phe Val Leu Gln Cys Ser Val Arg Gly Thr Pro Val Pro Arg 
    530                 535                 540                 


Ile Thr Trp Leu Leu Asn Gly Gln Pro Ile Gln Tyr Ala Arg Ser Thr 
545                 550                 555                 560 


Cys Glu Ala Gly Val Ala Glu Leu His Ile Gln Asp Ala Leu Pro Glu 
                565                 570                 575     


Asp His Gly Thr Tyr Thr Cys Leu Ala Glu Asn Ala Leu Gly Gln Val 
            580                 585                 590         


Ser Cys Ser Ala Trp Val Thr Val His Glu Lys Lys Ser Ser Arg Lys 
        595                 600                 605             


Ser Glu Tyr Leu Leu Pro Val Ala Pro Ser Lys Pro Thr Ala Pro Ile 
    610                 615                 620                 


Phe Leu Gln Gly Leu Ser Asp Leu Lys Val Met Asp Gly Ser Gln Val 
625                 630                 635                 640 


Thr Met Thr Val Gln Val Ser Gly Asn Pro Pro Pro Glu Val Ile Trp 
                645                 650                 655     


Leu His Asn Gly Asn Glu Ile Gln Glu Ser Glu Asp Phe His Phe Glu 
            660                 665                 670         


Gln Arg Gly Thr Gln His Ser Leu Cys Ile Gln Glu Val Phe Pro Glu 
        675                 680                 685             


Asp Thr Gly Thr Tyr Thr Cys Glu Ala Trp Asn Ser Ala Gly Glu Val 
    690                 695                 700                 


Arg Thr Gln Ala Val Leu Thr Val Gln Glu Pro His Asp Gly Thr Gln 
705                 710                 715                 720 


Pro Trp Phe Ile Ser Lys Pro Arg Ser Val Thr Ala Ser Leu Gly Gln 
                725                 730                 735     


Ser Val Leu Ile Ser Cys Ala Ile Ala Gly Asp Pro Phe Pro Thr Val 
            740                 745                 750         


His Trp Leu Arg Asp Gly Lys Ala Leu Cys Lys Asp Thr Gly His Phe 
        755                 760                 765             


Glu Val Leu Gln Asn Glu Asp Val Phe Thr Leu Val Leu Lys Lys Val 
    770                 775                 780                 


Gln Pro Trp His Ala Gly Gln Tyr Glu Ile Leu Leu Lys Asn Arg Val 
785                 790                 795                 800 


Gly Glu Cys Ser Cys Gln Val Ser Leu Met Leu Gln Asn Ser Ser Ala 
                805                 810                 815     


Arg Ala Leu Pro Arg Gly Arg Glu Pro Ala Ser Cys Glu Asp Leu Cys 
            820                 825                 830         


Gly Gly Gly Val Gly Ala Asp Gly Gly Gly Ser Asp Arg Tyr Gly Ser 
        835                 840                 845             


Leu Arg Pro Gly Trp Pro Ala Arg Gly Gln Gly Trp Leu Glu Glu Glu 
    850                 855                 860                 


Asp Gly Glu Asp Val Arg Gly Val Leu Lys Arg Arg Val Glu Thr Arg 
865                 870                 875                 880 


Gln His Thr Glu Glu Ala Ile Arg Gln Gln Glu Val Glu Gln Leu Asp 
                885                 890                 895     


Phe Arg Asp Leu Leu Gly Lys Lys Val Ser Thr Lys Thr Leu Ser Glu 
            900                 905                 910         


Asp Asp Leu Lys Glu Ile Pro Ala Glu Gln Met Asp Phe Arg Ala Asn 
        915                 920                 925             


Leu Gln Arg Gln Val Lys Pro Lys Thr Val Ser Glu Glu Glu Arg Lys 
    930                 935                 940                 


Val His Ser Pro Gln Gln Val Asp Phe Arg Ser Val Leu Ala Lys Lys 
945                 950                 955                 960 


Gly Thr Ser Lys Thr Pro Val Pro Glu Lys Val Pro Pro Pro Lys Pro 
                965                 970                 975     


Ala Thr Pro Asp Phe Arg Ser Val Leu Gly Gly Lys Lys Lys Leu Pro 
            980                 985                 990         


Ala Glu Asn Gly Ser Ser Ser Ala  Glu Thr Leu Asn Ala  Lys Ala Val 
        995                 1000                 1005             


Glu Ser  Ser Lys Pro Leu Ser  Asn Ala Gln Pro Ser  Gly Pro Leu 
    1010                 1015                 1020             


Lys Pro  Val Gly Asn Ala Lys  Pro Ala Glu Thr Leu  Lys Pro Met 
    1025                 1030                 1035             


Gly Asn  Ala Lys Pro Ala Glu  Thr Leu Lys Pro Met  Gly Asn Ala 
    1040                 1045                 1050             


Lys Pro  Asp Glu Asn Leu Lys  Ser Ala Ser Lys Glu  Glu Leu Lys 
    1055                 1060                 1065             


Lys Asp  Val Lys Asn Asp Val  Asn Cys Lys Arg Gly  His Ala Gly 
    1070                 1075                 1080             


Thr Thr  Asp Asn Glu Lys Arg  Ser Glu Ser Gln Gly  Thr Ala Pro 
    1085                 1090                 1095             


Ala Phe  Lys Gln Lys Leu Gln  Asp Val His Val Ala  Glu Gly Lys 
    1100                 1105                 1110             


Lys Leu  Leu Leu Gln Cys Gln  Val Ser Ser Asp Pro  Pro Ala Thr 
    1115                 1120                 1125             


Ile Ile  Trp Thr Leu Asn Gly  Lys Thr Leu Lys Thr  Thr Lys Phe 
    1130                 1135                 1140             


Ile Ile  Leu Ser Gln Glu Gly  Ser Leu Cys Ser Val  Ser Ile Glu 
    1145                 1150                 1155             


Lys Ala  Leu Pro Glu Asp Arg  Gly Leu Tyr Lys Cys  Val Ala Lys 
    1160                 1165                 1170             


Asn Asp  Ala Gly Gln Ala Glu  Cys Ser Cys Gln Val  Thr Val Asp 
    1175                 1180                 1185             


Asp Ala  Pro Ala Ser Glu Asn  Thr Lys Ala Pro Glu  Met Lys Ser 
    1190                 1195                 1200             


Arg Arg  Pro Lys Ser Ser Leu  Pro Pro Val Leu Gly  Thr Glu Ser 
    1205                 1210                 1215             


Asp Ala  Thr Val Lys Lys Lys  Pro Ala Pro Lys Thr  Pro Pro Lys 
    1220                 1225                 1230             


Ala Ala  Met Pro Pro Gln Ile  Ile Gln Phe Pro Glu  Asp Gln Lys 
    1235                 1240                 1245             


Val Arg  Ala Gly Glu Ser Val  Glu Leu Phe Gly Lys  Val Thr Gly 
    1250                 1255                 1260             


Thr Gln  Pro Ile Thr Cys Thr  Trp Met Lys Phe Arg  Lys Gln Ile 
    1265                 1270                 1275             


Gln Glu  Ser Glu His Met Lys  Val Glu Asn Ser Glu  Asn Gly Ser 
    1280                 1285                 1290             


Lys Leu  Thr Ile Leu Ala Ala  Arg Gln Glu His Cys  Gly Cys Tyr 
    1295                 1300                 1305             


Thr Leu  Leu Val Glu Asn Lys  Leu Gly Ser Arg Gln  Ala Gln Val 
    1310                 1315                 1320             


Asn Leu  Thr Val Val Asp Lys  Pro Asp Pro Pro Ala  Gly Thr Pro 
    1325                 1330                 1335             


Cys Ala  Ser Asp Ile Arg Ser  Ser Ser Leu Thr Leu  Ser Trp Tyr 
    1340                 1345                 1350             


Gly Ser  Ser Tyr Asp Gly Gly  Ser Ala Val Gln Ser  Tyr Ser Ile 
    1355                 1360                 1365             


Glu Ile  Trp Asp Ser Ala Asn  Lys Thr Trp Lys Glu  Leu Ala Thr 
    1370                 1375                 1380             


Cys Arg  Ser Thr Ser Phe Asn  Val Gln Asp Leu Leu  Pro Asp His 
    1385                 1390                 1395             


Glu Tyr  Lys Phe Arg Val Arg  Ala Ile Asn Val Tyr  Gly Thr Ser 
    1400                 1405                 1410             


Glu Pro  Ser Gln Glu Ser Glu  Leu Thr Thr Val Gly  Glu Lys Pro 
    1415                 1420                 1425             


Glu Glu  Pro Lys Asp Glu Val  Glu Val Ser Asp Asp  Asp Glu Lys 
    1430                 1435                 1440             


Glu Pro  Glu Val Asp Tyr Arg  Thr Val Thr Ile Asn  Thr Glu Gln 
    1445                 1450                 1455             


Lys Val  Ser Asp Phe Tyr Asp  Ile Glu Glu Arg Leu  Gly Ser Gly 
    1460                 1465                 1470             


Lys Phe  Gly Gln Val Phe Arg  Leu Val Glu Lys Lys  Thr Arg Lys 
    1475                 1480                 1485             


Val Trp  Ala Gly Lys Phe Phe  Lys Ala Tyr Ser Ala  Lys Glu Lys 
    1490                 1495                 1500             


Glu Asn  Ile Arg Gln Glu Ile  Ser Ile Met Asn Cys  Leu His His 
    1505                 1510                 1515             


Pro Lys  Leu Val Gln Cys Val  Asp Ala Phe Glu Glu  Lys Ala Asn 
    1520                 1525                 1530             


Ile Val  Met Val Leu Glu Ile  Val Ser Gly Gly Glu  Leu Phe Glu 
    1535                 1540                 1545             


Arg Ile  Ile Asp Glu Asp Phe  Glu Leu Thr Glu Arg  Glu Cys Ile 
    1550                 1555                 1560             


Lys Tyr  Met Arg Gln Ile Ser  Glu Gly Val Glu Tyr  Ile His Lys 
    1565                 1570                 1575             


Gln Gly  Ile Val His Leu Asp  Leu Lys Pro Glu Asn  Ile Met Cys 
    1580                 1585                 1590             


Val Asn  Lys Thr Gly Thr Arg  Ile Lys Leu Ile Asp  Phe Gly Leu 
    1595                 1600                 1605             


Ala Arg  Arg Leu Glu Asn Ala  Gly Ser Leu Lys Val  Leu Phe Gly 
    1610                 1615                 1620             


Thr Pro  Glu Phe Val Ala Pro  Glu Val Ile Asn Tyr  Glu Pro Ile 
    1625                 1630                 1635             


Gly Tyr  Ala Thr Asp Met Trp  Ser Ile Gly Val Ile  Cys Tyr Ile 
    1640                 1645                 1650             


Leu Asn  Arg Leu Asp Cys Thr  Gln Cys Leu Gln His  Pro Trp Leu 
    1655                 1660                 1665             


Met Lys  Asp Thr Lys Asn Met  Glu Ala Lys Lys Leu  Ser Lys Asp 
    1670                 1675                 1680             


Arg Met  Lys Lys Tyr Met Ala  Arg Arg Lys Trp Gln  Lys Thr Gly 
    1685                 1690                 1695             


Asn Ala  Val Arg Ala Ile Gly  Arg Leu Ser Ser Met  Ala Met Ile 
    1700                 1705                 1710             


Ser Gly  Leu Ser Gly Arg Lys  Ser Ser Thr Gly Ser  Pro Thr Ser 
    1715                 1720                 1725             


Pro Leu  Asn Ala Glu Lys Leu  Glu Ser Glu Glu Asp  Val Ser Gln 
    1730                 1735                 1740             


Ala Phe  Leu Glu Ala Val Ala  Glu Glu Lys Pro His  Val Lys Pro 
    1745                 1750                 1755             


Tyr Phe  Ser Lys Thr Ile Arg  Asp Leu Glu Val Val  Glu Gly Ser 
    1760                 1765                 1770             


Ala Ala  Arg Phe Asp Cys Lys  Ile Glu Gly Tyr Pro  Asp Pro Glu 
    1775                 1780                 1785             


Val Val  Trp Phe Lys Asp Asp  Gln Ser Ile Arg Glu  Ser Arg His 
    1790                 1795                 1800             


Phe Gln  Ile Asp Tyr Asp Glu  Asp Gly Asn Cys Ser  Leu Ile Ile 
    1805                 1810                 1815             


Ser Asp  Val Cys Gly Asp Asp  Asp Ala Lys Tyr Thr  Cys Lys Ala 
    1820                 1825                 1830             


Val Asn  Ser Leu Gly Glu Ala  Thr Cys Thr Ala Glu  Leu Ile Val 
    1835                 1840                 1845             


Glu Thr  Met Glu Glu Gly Glu  Gly Glu Gly Glu Glu  Glu Glu Glu 
    1850                 1855                 1860             


<210>  3720
<211>  422
<212>  PRT
<213>  homo sapiens

<400>  3720

Met Gln Asn Ser His Ser Gly Val Asn Gln Leu Gly Gly Val Phe Val 
1               5                   10                  15      


Asn Gly Arg Pro Leu Pro Asp Ser Thr Arg Gln Lys Ile Val Glu Leu 
            20                  25                  30          


Ala His Ser Gly Ala Arg Pro Cys Asp Ile Ser Arg Ile Leu Gln Val 
        35                  40                  45              


Ser Asn Gly Cys Val Ser Lys Ile Leu Gly Arg Tyr Tyr Glu Thr Gly 
    50                  55                  60                  


Ser Ile Arg Pro Arg Ala Ile Gly Gly Ser Lys Pro Arg Val Ala Thr 
65                  70                  75                  80  


Pro Glu Val Val Ser Lys Ile Ala Gln Tyr Lys Arg Glu Cys Pro Ser 
                85                  90                  95      


Ile Phe Ala Trp Glu Ile Arg Asp Arg Leu Leu Ser Glu Gly Val Cys 
            100                 105                 110         


Thr Asn Asp Asn Ile Pro Ser Val Ser Ser Ile Asn Arg Val Leu Arg 
        115                 120                 125             


Asn Leu Ala Ser Glu Lys Gln Gln Met Gly Ala Asp Gly Met Tyr Asp 
    130                 135                 140                 


Lys Leu Arg Met Leu Asn Gly Gln Thr Gly Ser Trp Gly Thr Arg Pro 
145                 150                 155                 160 


Gly Trp Tyr Pro Gly Thr Ser Val Pro Gly Gln Pro Thr Gln Asp Gly 
                165                 170                 175     


Cys Gln Gln Gln Glu Gly Gly Gly Glu Asn Thr Asn Ser Ile Ser Ser 
            180                 185                 190         


Asn Gly Glu Asp Ser Asp Glu Ala Gln Met Arg Leu Gln Leu Lys Arg 
        195                 200                 205             


Lys Leu Gln Arg Asn Arg Thr Ser Phe Thr Gln Glu Gln Ile Glu Ala 
    210                 215                 220                 


Leu Glu Lys Glu Phe Glu Arg Thr His Tyr Pro Asp Val Phe Ala Arg 
225                 230                 235                 240 


Glu Arg Leu Ala Ala Lys Ile Asp Leu Pro Glu Ala Arg Ile Gln Val 
                245                 250                 255     


Trp Phe Ser Asn Arg Arg Ala Lys Trp Arg Arg Glu Glu Lys Leu Arg 
            260                 265                 270         


Asn Gln Arg Arg Gln Ala Ser Asn Thr Pro Ser His Ile Pro Ile Ser 
        275                 280                 285             


Ser Ser Phe Ser Thr Ser Val Tyr Gln Pro Ile Pro Gln Pro Thr Thr 
    290                 295                 300                 


Pro Val Ser Ser Phe Thr Ser Gly Ser Met Leu Gly Arg Thr Asp Thr 
305                 310                 315                 320 


Ala Leu Thr Asn Thr Tyr Ser Ala Leu Pro Pro Met Pro Ser Phe Thr 
                325                 330                 335     


Met Ala Asn Asn Leu Pro Met Gln Pro Pro Val Pro Ser Gln Thr Ser 
            340                 345                 350         


Ser Tyr Ser Cys Met Leu Pro Thr Ser Pro Ser Val Asn Gly Arg Ser 
        355                 360                 365             


Tyr Asp Thr Tyr Thr Pro Pro His Met Gln Thr His Met Asn Ser Gln 
    370                 375                 380                 


Pro Met Gly Thr Ser Gly Thr Thr Ser Thr Gly Leu Ile Ser Pro Gly 
385                 390                 395                 400 


Val Ser Val Pro Val Gln Val Pro Gly Ser Glu Pro Asp Met Ser Gln 
                405                 410                 415     


Tyr Trp Pro Arg Leu Gln 
            420         


<210>  3721
<211>  588
<212>  PRT
<213>  homo sapiens

<400>  3721

Met His Cys Lys Val Ser Leu Leu Asp Asp Thr Val Tyr Glu Cys Val 
1               5                   10                  15      


Val Glu Lys His Ala Lys Gly Gln Asp Leu Leu Lys Arg Val Cys Glu 
            20                  25                  30          


His Leu Asn Leu Leu Glu Glu Asp Tyr Phe Gly Leu Ala Ile Trp Asp 
        35                  40                  45              


Asn Ala Thr Ser Lys Thr Trp Leu Asp Ser Ala Lys Glu Ile Lys Lys 
    50                  55                  60                  


Gln Val Arg Gly Val Pro Trp Asn Phe Thr Phe Asn Val Lys Phe Tyr 
65                  70                  75                  80  


Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr Leu 
                85                  90                  95      


Cys Leu Gln Leu Arg Gln Asp Ile Val Ala Gly Arg Leu Pro Cys Ser 
            100                 105                 110         


Phe Ala Thr Leu Ala Leu Leu Gly Ser Tyr Thr Ile Gln Ser Glu Leu 
        115                 120                 125             


Gly Asp Tyr Asp Pro Glu Leu His Gly Val Asp Tyr Val Ser Asp Phe 
    130                 135                 140                 


Lys Leu Ala Pro Asn Gln Thr Lys Glu Leu Glu Glu Lys Val Met Glu 
145                 150                 155                 160 


Leu His Lys Ser Tyr Arg Ser Met Thr Pro Ala Gln Ala Asp Leu Glu 
                165                 170                 175     


Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His 
            180                 185                 190         


Lys Ala Lys Asp Leu Glu Gly Val Asp Ile Ile Leu Gly Val Cys Ser 
        195                 200                 205             


Ser Gly Leu Leu Val Tyr Lys Asp Lys Leu Arg Ile Asn Arg Phe Pro 
    210                 215                 220                 


Trp Pro Lys Val Leu Lys Ile Ser Tyr Lys Arg Ser Ser Phe Phe Ile 
225                 230                 235                 240 


Lys Ile Arg Pro Gly Glu Gln Glu Gln Tyr Glu Ser Thr Ile Gly Phe 
                245                 250                 255     


Lys Leu Pro Ser Tyr Arg Ala Ala Lys Lys Leu Trp Lys Val Cys Val 
            260                 265                 270         


Glu His His Thr Phe Phe Arg Leu Thr Ser Thr Asp Thr Ile Pro Lys 
        275                 280                 285             


Ser Lys Phe Leu Ala Leu Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr 
    290                 295                 300                 


Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro 
305                 310                 315                 320 


His Phe Glu Arg Thr Ala Ser Lys Arg Ala Ser Arg Ser Leu Asp Gly 
                325                 330                 335     


Ala Ala Ala Val Asp Ser Ala Asp Arg Ser Pro Arg Pro Thr Ser Ala 
            340                 345                 350         


Pro Ala Ile Thr Gln Gly Gln Val Ala Glu Gly Gly Val Leu Asp Ala 
        355                 360                 365             


Ser Ala Lys Lys Thr Val Val Pro Lys Ala Gln Lys Glu Thr Val Lys 
    370                 375                 380                 


Ala Glu Val Lys Lys Glu Asp Glu Pro Pro Glu Gln Ala Glu Pro Glu 
385                 390                 395                 400 


Pro Thr Glu Ala Trp Lys Lys Lys Arg Glu Arg Leu Asp Gly Glu Asn 
                405                 410                 415     


Ile Tyr Ile Arg His Ser Asn Leu Met Leu Glu Asp Leu Asp Lys Ser 
            420                 425                 430         


Gln Glu Glu Ile Lys Lys His His Ala Ser Ile Ser Glu Leu Lys Lys 
        435                 440                 445             


Asn Phe Met Glu Ser Val Pro Glu Pro Arg Pro Ser Glu Trp Asp Lys 
    450                 455                 460                 


Arg Leu Ser Thr His Ser Pro Phe Arg Thr Leu Asn Ile Asn Gly Gln 
465                 470                 475                 480 


Ile Pro Thr Gly Glu Gly Pro Pro Leu Val Lys Thr Gln Thr Val Thr 
                485                 490                 495     


Ile Ser Asp Asn Ala Asn Ala Val Lys Ser Glu Ile Pro Thr Lys Asp 
            500                 505                 510         


Val Pro Ile Val His Thr Glu Thr Lys Thr Ile Thr Tyr Glu Ala Ala 
        515                 520                 525             


Gln Thr Val Lys Gly Gly Ile Ser Glu Thr Arg Ile Glu Lys Arg Ile 
    530                 535                 540                 


Val Ile Thr Gly Asp Ala Asp Ile Asp His Asp Gln Val Leu Val Gln 
545                 550                 555                 560 


Ala Ile Lys Glu Ala Lys Glu Gln His Pro Asp Met Ser Val Thr Lys 
                565                 570                 575     


Val Val Val His Gln Glu Thr Glu Ile Ala Asp Glu 
            580                 585             


<210>  3722
<211>  775
<212>  PRT
<213>  homo sapiens

<400>  3722

Met Thr Thr Glu Lys Ser Leu Val Thr Glu Ala Glu Asn Ser Gln His 
1               5                   10                  15      


Gln Gln Lys Glu Glu Gly Glu Glu Ala Ile Asn Ser Gly Gln Gln Glu 
            20                  25                  30          


Pro Gln Gln Glu Glu Ser Cys Gln Thr Ala Ala Glu Gly Asp Asn Trp 
        35                  40                  45              


Cys Glu Gln Lys Leu Lys Ala Ser Asn Gly Asp Thr Pro Thr His Glu 
    50                  55                  60                  


Asp Leu Thr Lys Asn Lys Glu Arg Thr Ser Glu Ser Arg Gly Leu Ser 
65                  70                  75                  80  


Arg Leu Phe Ser Ser Phe Leu Lys Arg Pro Lys Ser Gln Val Ser Glu 
                85                  90                  95      


Glu Glu Gly Lys Glu Val Glu Ser Asp Lys Glu Lys Gly Glu Gly Gly 
            100                 105                 110         


Gln Lys Glu Ile Glu Phe Gly Thr Ser Leu Asp Glu Glu Ile Ile Leu 
        115                 120                 125             


Lys Ala Pro Ile Ala Ala Pro Glu Pro Glu Leu Lys Thr Asp Pro Ser 
    130                 135                 140                 


Leu Asp Leu His Ser Leu Ser Ser Ala Glu Thr Gln Pro Ala Gln Glu 
145                 150                 155                 160 


Glu Leu Arg Glu Asp Pro Asp Phe Glu Ile Lys Glu Gly Glu Gly Leu 
                165                 170                 175     


Glu Glu Cys Ser Lys Ile Glu Val Lys Glu Glu Ser Pro Gln Ser Lys 
            180                 185                 190         


Ala Glu Thr Glu Leu Lys Ala Ser Gln Lys Pro Ile Arg Lys His Arg 
        195                 200                 205             


Asn Met His Cys Lys Val Ser Leu Leu Asp Asp Thr Val Tyr Glu Cys 
    210                 215                 220                 


Val Val Glu Thr Trp Leu Asp Ser Ala Lys Glu Ile Lys Lys Gln Val 
225                 230                 235                 240 


Arg Gly Val Pro Trp Asn Phe Thr Phe Asn Val Lys Phe Tyr Pro Pro 
                245                 250                 255     


Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr Leu Cys Leu 
            260                 265                 270         


Gln Leu Arg Gln Asp Ile Val Ala Gly Arg Leu Pro Cys Ser Phe Ala 
        275                 280                 285             


Thr Leu Ala Leu Leu Gly Ser Tyr Thr Ile Gln Ser Glu Leu Gly Asp 
    290                 295                 300                 


Tyr Asp Pro Glu Leu His Gly Val Asp Tyr Val Ser Asp Phe Lys Leu 
305                 310                 315                 320 


Ala Pro Asn Gln Thr Lys Glu Leu Glu Glu Lys Val Met Glu Leu His 
                325                 330                 335     


Lys Ser Tyr Arg Ser Met Thr Pro Ala Gln Ala Asp Leu Glu Phe Leu 
            340                 345                 350         


Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His Lys Ala 
        355                 360                 365             


Lys Asp Leu Glu Gly Val Asp Ile Ile Leu Gly Val Cys Ser Ser Gly 
    370                 375                 380                 


Leu Leu Val Tyr Lys Asp Lys Leu Arg Ile Asn Arg Phe Pro Trp Pro 
385                 390                 395                 400 


Lys Val Leu Lys Ile Ser Tyr Lys Arg Ser Ser Phe Phe Ile Lys Ile 
                405                 410                 415     


Arg Pro Gly Glu Gln Glu Gln Tyr Glu Ser Thr Ile Gly Phe Lys Leu 
            420                 425                 430         


Pro Ser Tyr Arg Ala Ala Lys Lys Leu Trp Lys Val Cys Val Glu His 
        435                 440                 445             


His Thr Phe Phe Arg Leu Thr Ser Thr Asp Thr Ile Pro Lys Ser Lys 
    450                 455                 460                 


Phe Leu Ala Leu Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr Gln Ala 
465                 470                 475                 480 


Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro His Phe 
                485                 490                 495     


Glu Arg Thr Ala Ser Lys Arg Ala Ser Arg Ser Leu Asp Gly Ala Ala 
            500                 505                 510         


Ala Val Asp Ser Ala Asp Arg Ser Pro Arg Pro Thr Ser Ala Pro Ala 
        515                 520                 525             


Ile Thr Gln Gly Gln Val Ala Glu Gly Gly Val Leu Asp Ala Ser Ala 
    530                 535                 540                 


Lys Lys Thr Val Val Pro Lys Ala Gln Lys Glu Thr Val Lys Ala Glu 
545                 550                 555                 560 


Val Lys Lys Glu Asp Glu Pro Pro Glu Gln Ala Glu Pro Glu Pro Thr 
                565                 570                 575     


Glu Ala Trp Lys Asp Leu Asp Lys Ser Gln Glu Glu Ile Lys Lys His 
            580                 585                 590         


His Ala Ser Ile Ser Glu Leu Lys Lys Asn Phe Met Glu Ser Val Pro 
        595                 600                 605             


Glu Pro Arg Pro Ser Glu Trp Asp Lys Arg Leu Ser Thr His Ser Pro 
    610                 615                 620                 


Phe Arg Thr Leu Asn Ile Asn Gly Gln Ile Pro Thr Gly Glu Gly Pro 
625                 630                 635                 640 


Pro Leu Val Lys Thr Gln Thr Val Thr Ile Ser Asp Asn Ala Asn Ala 
                645                 650                 655     


Val Lys Ser Glu Ile Pro Thr Lys Asp Val Pro Ile Val His Thr Glu 
            660                 665                 670         


Thr Lys Thr Ile Thr Tyr Glu Ala Ala Gln Thr Asp Asp Asn Ser Gly 
        675                 680                 685             


Asp Leu Asp Pro Gly Val Leu Leu Thr Ala Gln Thr Ile Thr Ser Glu 
    690                 695                 700                 


Thr Pro Ser Ser Thr Thr Thr Thr Gln Ile Thr Lys Thr Val Lys Gly 
705                 710                 715                 720 


Gly Ile Ser Glu Thr Arg Ile Glu Lys Arg Ile Val Ile Thr Gly Asp 
                725                 730                 735     


Ala Asp Ile Asp His Asp Gln Val Leu Val Gln Ala Ile Lys Glu Ala 
            740                 745                 750         


Lys Glu Gln His Pro Asp Met Ser Val Thr Lys Val Val Val His Gln 
        755                 760                 765             


Glu Thr Glu Ile Ala Asp Glu 
    770                 775 


<210>  3723
<211>  641
<212>  PRT
<213>  homo sapiens

<400>  3723

Met His Cys Lys Val Ser Leu Leu Asp Asp Thr Val Tyr Glu Cys Val 
1               5                   10                  15      


Val Glu Lys His Ala Lys Gly Gln Asp Leu Leu Lys Arg Val Cys Glu 
            20                  25                  30          


His Leu Asn Leu Leu Glu Glu Asp Tyr Phe Gly Leu Ala Ile Trp Asp 
        35                  40                  45              


Asn Ala Thr Ser Lys Thr Trp Leu Asp Ser Ala Lys Glu Ile Lys Lys 
    50                  55                  60                  


Gln Val Arg Gly Val Pro Trp Asn Phe Thr Phe Asn Val Lys Phe Tyr 
65                  70                  75                  80  


Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr Leu 
                85                  90                  95      


Cys Leu Gln Leu Arg Gln Asp Ile Val Ala Gly Arg Leu Pro Cys Ser 
            100                 105                 110         


Phe Ala Thr Leu Ala Leu Leu Gly Ser Tyr Thr Ile Gln Ser Glu Leu 
        115                 120                 125             


Gly Asp Tyr Asp Pro Glu Leu His Gly Val Asp Tyr Val Ser Asp Phe 
    130                 135                 140                 


Lys Leu Ala Pro Asn Gln Thr Lys Glu Leu Glu Glu Lys Val Met Glu 
145                 150                 155                 160 


Leu His Lys Ser Tyr Arg Ser Met Thr Pro Ala Gln Ala Asp Leu Glu 
                165                 170                 175     


Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His 
            180                 185                 190         


Lys Ala Lys Asp Leu Glu Gly Val Asp Ile Ile Leu Gly Val Cys Ser 
        195                 200                 205             


Ser Gly Leu Leu Val Tyr Lys Asp Lys Leu Arg Ile Asn Arg Phe Pro 
    210                 215                 220                 


Trp Pro Lys Val Leu Lys Ile Ser Tyr Lys Arg Ser Ser Phe Phe Ile 
225                 230                 235                 240 


Lys Ile Arg Pro Gly Glu Gln Glu Gln Tyr Glu Ser Thr Ile Gly Phe 
                245                 250                 255     


Lys Leu Pro Ser Tyr Arg Ala Ala Lys Lys Leu Trp Lys Val Cys Val 
            260                 265                 270         


Glu His His Thr Phe Phe Arg Leu Thr Ser Thr Asp Thr Ile Pro Lys 
        275                 280                 285             


Ser Lys Phe Leu Ala Leu Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr 
    290                 295                 300                 


Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro 
305                 310                 315                 320 


His Phe Glu Arg Thr Ala Ser Lys Arg Ala Ser Arg Ser Leu Asp Gly 
                325                 330                 335     


Ala Ala Ala Val Asp Ser Ala Asp Arg Ser Pro Arg Pro Thr Ser Ala 
            340                 345                 350         


Pro Ala Ile Thr Gln Gly Gln Val Ala Glu Gly Gly Val Leu Asp Ala 
        355                 360                 365             


Ser Ala Lys Lys Thr Val Val Pro Lys Ala Gln Lys Glu Thr Val Lys 
    370                 375                 380                 


Ala Glu Val Lys Lys Glu Asp Glu Pro Pro Glu Gln Ala Glu Pro Glu 
385                 390                 395                 400 


Pro Thr Glu Ala Trp Lys Val Glu Lys Thr His Ile Glu Val Thr Val 
                405                 410                 415     


Pro Thr Ser Asn Gly Asp Gln Thr Gln Lys Lys Arg Glu Arg Leu Asp 
            420                 425                 430         


Gly Glu Asn Ile Tyr Ile Arg His Ser Asn Leu Met Leu Glu Asp Leu 
        435                 440                 445             


Asp Lys Ser Gln Glu Glu Ile Lys Lys His His Ala Ser Ile Ser Glu 
    450                 455                 460                 


Leu Lys Lys Asn Phe Met Glu Ser Val Pro Glu Pro Arg Pro Ser Glu 
465                 470                 475                 480 


Trp Asp Lys Arg Leu Ser Thr His Ser Pro Phe Arg Thr Leu Asn Ile 
                485                 490                 495     


Asn Gly Gln Ile Pro Thr Gly Glu Gly Pro Pro Leu Val Lys Thr Gln 
            500                 505                 510         


Thr Val Thr Ile Ser Asp Asn Ala Asn Ala Val Lys Ser Glu Ile Pro 
        515                 520                 525             


Thr Lys Asp Val Pro Ile Val His Thr Glu Thr Lys Thr Ile Thr Tyr 
    530                 535                 540                 


Glu Ala Ala Gln Thr Asp Asp Asn Ser Gly Asp Leu Asp Pro Gly Val 
545                 550                 555                 560 


Leu Leu Thr Ala Gln Thr Ile Thr Ser Glu Thr Pro Ser Ser Thr Thr 
                565                 570                 575     


Thr Thr Gln Ile Thr Lys Thr Val Lys Gly Gly Ile Ser Glu Thr Arg 
            580                 585                 590         


Ile Glu Lys Arg Ile Val Ile Thr Gly Asp Ala Asp Ile Asp His Asp 
        595                 600                 605             


Gln Val Leu Val Gln Ala Ile Lys Glu Ala Lys Glu Gln His Pro Asp 
    610                 615                 620                 


Met Ser Val Thr Lys Val Val Val His Gln Glu Thr Glu Ile Ala Asp 
625                 630                 635                 640 


Glu 
    


<210>  3724
<211>  864
<212>  PRT
<213>  homo sapiens

<400>  3724

Met Thr Thr Glu Lys Ser Leu Val Thr Glu Ala Glu Asn Ser Gln His 
1               5                   10                  15      


Gln Gln Lys Glu Glu Gly Glu Glu Ala Ile Asn Ser Gly Gln Gln Glu 
            20                  25                  30          


Pro Gln Gln Glu Glu Ser Cys Gln Thr Ala Ala Glu Gly Asp Asn Trp 
        35                  40                  45              


Cys Glu Gln Lys Leu Lys Ala Ser Asn Gly Asp Thr Pro Thr His Glu 
    50                  55                  60                  


Asp Leu Thr Lys Asn Lys Glu Arg Thr Ser Glu Ser Arg Gly Leu Ser 
65                  70                  75                  80  


Arg Leu Phe Ser Ser Phe Leu Lys Arg Pro Lys Ser Gln Val Ser Glu 
                85                  90                  95      


Glu Glu Gly Lys Glu Val Glu Ser Asp Lys Glu Lys Gly Glu Gly Gly 
            100                 105                 110         


Gln Lys Glu Ile Glu Phe Gly Thr Ser Leu Asp Glu Glu Ile Ile Leu 
        115                 120                 125             


Lys Ala Pro Ile Ala Ala Pro Glu Pro Glu Leu Lys Thr Asp Pro Ser 
    130                 135                 140                 


Leu Asp Leu His Ser Leu Ser Ser Ala Glu Thr Gln Pro Ala Gln Glu 
145                 150                 155                 160 


Glu Leu Arg Glu Asp Pro Asp Phe Glu Ile Lys Glu Gly Glu Gly Leu 
                165                 170                 175     


Glu Glu Cys Ser Lys Ile Glu Val Lys Glu Glu Ser Pro Gln Ser Lys 
            180                 185                 190         


Ala Glu Thr Glu Leu Lys Ala Ser Gln Lys Pro Ile Arg Lys His Arg 
        195                 200                 205             


Asn Met His Cys Lys Val Ser Leu Leu Asp Asp Thr Val Tyr Glu Cys 
    210                 215                 220                 


Val Val Glu Lys His Ala Lys Gly Gln Asp Leu Leu Lys Arg Val Cys 
225                 230                 235                 240 


Glu His Leu Asn Leu Leu Glu Glu Asp Tyr Phe Gly Leu Ala Ile Trp 
                245                 250                 255     


Asp Asn Ala Thr Ser Lys Thr Trp Leu Asp Ser Ala Lys Glu Ile Lys 
            260                 265                 270         


Lys Gln Val Arg Gly Val Pro Trp Asn Phe Thr Phe Asn Val Lys Phe 
        275                 280                 285             


Tyr Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr 
    290                 295                 300                 


Leu Cys Leu Gln Leu Arg Gln Asp Ile Val Ala Gly Arg Leu Pro Cys 
305                 310                 315                 320 


Ser Phe Ala Thr Leu Ala Leu Leu Gly Ser Tyr Thr Ile Gln Ser Glu 
                325                 330                 335     


Leu Gly Asp Tyr Asp Pro Glu Leu His Gly Val Asp Tyr Val Ser Asp 
            340                 345                 350         


Phe Lys Leu Ala Pro Asn Gln Thr Lys Glu Leu Glu Glu Lys Val Met 
        355                 360                 365             


Glu Leu His Lys Ser Tyr Arg Ser Met Thr Pro Ala Gln Ala Asp Leu 
    370                 375                 380                 


Glu Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu 
385                 390                 395                 400 


His Lys Ala Lys Asp Leu Glu Gly Val Asp Ile Ile Leu Gly Val Cys 
                405                 410                 415     


Ser Ser Gly Leu Leu Val Tyr Lys Asp Lys Leu Arg Ile Asn Arg Phe 
            420                 425                 430         


Pro Trp Pro Lys Val Leu Lys Ile Ser Tyr Lys Arg Ser Ser Phe Phe 
        435                 440                 445             


Ile Lys Ile Arg Pro Gly Glu Gln Glu Gln Tyr Glu Ser Thr Ile Gly 
    450                 455                 460                 


Phe Lys Leu Pro Ser Tyr Arg Ala Ala Lys Lys Leu Trp Lys Val Cys 
465                 470                 475                 480 


Val Glu His His Thr Phe Phe Arg Leu Thr Ser Thr Asp Thr Ile Pro 
                485                 490                 495     


Lys Ser Lys Phe Leu Ala Leu Gly Ser Lys Phe Arg Tyr Ser Gly Arg 
            500                 505                 510         


Thr Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala 
        515                 520                 525             


Pro His Phe Glu Arg Thr Ala Ser Lys Arg Ala Ser Arg Ser Leu Asp 
    530                 535                 540                 


Gly Ala Ala Ala Val Asp Ser Ala Asp Arg Ser Pro Arg Pro Thr Ser 
545                 550                 555                 560 


Ala Pro Ala Ile Thr Gln Gly Gln Val Ala Glu Gly Gly Val Leu Asp 
                565                 570                 575     


Ala Ser Ala Lys Lys Thr Val Val Pro Lys Ala Gln Lys Glu Thr Val 
            580                 585                 590         


Lys Ala Glu Val Lys Lys Glu Asp Glu Pro Pro Glu Gln Ala Glu Pro 
        595                 600                 605             


Glu Pro Thr Glu Ala Trp Lys Val Glu Lys Thr His Ile Glu Val Thr 
    610                 615                 620                 


Val Pro Thr Ser Asn Gly Asp Gln Thr Gln Lys Leu Ala Glu Lys Thr 
625                 630                 635                 640 


Glu Asp Leu Ile Arg Met Arg Lys Lys Lys Arg Glu Arg Leu Asp Gly 
                645                 650                 655     


Glu Asn Ile Tyr Ile Arg His Ser Asn Leu Met Leu Glu Asp Leu Asp 
            660                 665                 670         


Lys Ser Gln Glu Glu Ile Lys Lys His His Ala Ser Ile Ser Glu Leu 
        675                 680                 685             


Lys Lys Asn Phe Met Glu Ser Val Pro Glu Pro Arg Pro Ser Glu Trp 
    690                 695                 700                 


Asp Lys Arg Leu Ser Thr His Ser Pro Phe Arg Thr Leu Asn Ile Asn 
705                 710                 715                 720 


Gly Gln Ile Pro Thr Gly Glu Gly Pro Pro Leu Val Lys Thr Gln Thr 
                725                 730                 735     


Val Thr Ile Ser Asp Asn Ala Asn Ala Val Lys Ser Glu Ile Pro Thr 
            740                 745                 750         


Lys Asp Val Pro Ile Val His Thr Glu Thr Lys Thr Ile Thr Tyr Glu 
        755                 760                 765             


Ala Ala Gln Thr Asp Asp Asn Ser Gly Asp Leu Asp Pro Gly Val Leu 
    770                 775                 780                 


Leu Thr Ala Gln Thr Ile Thr Ser Glu Thr Pro Ser Ser Thr Thr Thr 
785                 790                 795                 800 


Thr Gln Ile Thr Lys Thr Val Lys Gly Gly Ile Ser Glu Thr Arg Ile 
                805                 810                 815     


Glu Lys Arg Ile Val Ile Thr Gly Asp Ala Asp Ile Asp His Asp Gln 
            820                 825                 830         


Val Leu Val Gln Ala Ile Lys Glu Ala Lys Glu Gln His Pro Asp Met 
        835                 840                 845             


Ser Val Thr Lys Val Val Val His Gln Glu Thr Glu Ile Ala Asp Glu 
    850                 855                 860                 


<210>  3725
<211>  468
<212>  PRT
<213>  homo sapiens

<400>  3725

Met Ala Ala Ser Ser Asn Ser Ser Leu Ser Gly Ser Ser Val Ser Ser 
1               5                   10                  15      


Asp Ala Glu Glu Tyr Gln Pro Pro Ile Trp Lys Ser Tyr Leu Tyr Gln 
            20                  25                  30          


Leu Gln Gln Glu Ala Pro Arg Pro Lys Arg Ile Ile Cys Pro Arg Glu 
        35                  40                  45              


Val Glu Asn Arg Pro Lys Tyr Tyr Gly Arg Glu Phe His Gly Ile Ile 
    50                  55                  60                  


Ser Arg Glu Gln Ala Asp Glu Leu Leu Gly Gly Val Glu Gly Ala Tyr 
65                  70                  75                  80  


Ile Leu Arg Glu Ser Gln Arg Gln Pro Gly Cys Tyr Thr Leu Ala Leu 
                85                  90                  95      


Arg Phe Gly Asn Gln Thr Leu Asn Tyr Arg Leu Phe His Asp Gly Lys 
            100                 105                 110         


His Phe Val Gly Glu Lys Arg Phe Glu Ser Ile His Asp Leu Val Thr 
        115                 120                 125             


Asp Gly Leu Ile Thr Leu Tyr Ile Glu Thr Lys Ala Ala Glu Tyr Ile 
    130                 135                 140                 


Ser Lys Met Thr Thr Asn Pro Ile Tyr Glu His Ile Gly Tyr Ala Thr 
145                 150                 155                 160 


Leu Leu Arg Glu Lys Val Ser Arg Arg Leu Ser Arg Ser Lys Asn Glu 
                165                 170                 175     


Pro Arg Lys Thr Asn Val Thr His Glu Glu His Thr Ala Val Glu Lys 
            180                 185                 190         


Ile Ser Ser Leu Val Arg Arg Ala Ala Leu Thr His Asn Asp Asn His 
        195                 200                 205             


Phe Asn Tyr Glu Lys Thr His Asn Phe Lys Val His Thr Phe Arg Gly 
    210                 215                 220                 


Pro His Trp Cys Glu Tyr Cys Ala Asn Phe Met Trp Gly Leu Ile Ala 
225                 230                 235                 240 


Gln Gly Val Arg Cys Ser Asp Cys Gly Leu Asn Val His Lys Gln Cys 
                245                 250                 255     


Ser Lys His Val Pro Asn Asp Cys Gln Pro Asp Leu Lys Arg Ile Lys 
            260                 265                 270         


Lys Val Tyr Cys Cys Asp Leu Thr Thr Leu Val Lys Ala His Asn Thr 
        275                 280                 285             


Gln Arg Pro Met Val Val Asp Ile Cys Ile Arg Glu Ile Glu Ala Arg 
    290                 295                 300                 


Gly Leu Lys Ser Glu Gly Leu Tyr Arg Val Ser Gly Phe Thr Glu His 
305                 310                 315                 320 


Ile Glu Asp Val Lys Met Ala Phe Asp Arg Asp Gly Glu Lys Ala Asp 
                325                 330                 335     


Ile Ser Ala Asn Val Tyr Pro Asp Ile Asn Ile Ile Thr Gly Ala Leu 
            340                 345                 350         


Lys Leu Tyr Phe Arg Asp Leu Pro Ile Pro Val Ile Thr Tyr Asp Thr 
        355                 360                 365             


Tyr Ser Lys Phe Ile Asp Ala Ala Lys Ile Ser Asn Ala Asp Glu Arg 
    370                 375                 380                 


Leu Glu Ala Val His Glu Val Leu Met Leu Leu Pro Pro Ala His Tyr 
385                 390                 395                 400 


Glu Thr Leu Arg Tyr Leu Met Ile His Leu Lys Lys Val Thr Met Asn 
                405                 410                 415     


Glu Lys Asp Asn Phe Met Asn Ala Glu Asn Leu Gly Ile Val Phe Gly 
            420                 425                 430         


Pro Thr Leu Met Arg Pro Pro Glu Asp Ser Thr Leu Thr Thr Leu His 
        435                 440                 445             


Asp Met Arg Tyr Gln Lys Leu Ile Val Gln Ile Leu Ile Glu Asn Glu 
    450                 455                 460                 


Asp Val Leu Phe 
465             


<210>  3726
<211>  679
<212>  PRT
<213>  homo sapiens

<400>  3726

Met Gly Gln Ala Ala Glu Pro Thr Gly Tyr Met Glu Asn Ser Val Ser 
1               5                   10                  15      


Tyr Ser Ala Ile Glu Asp Val Gln Leu Leu Ser Trp Glu Asn Ala Pro 
            20                  25                  30          


Lys Tyr Cys Leu Gln Leu Thr Ile Pro Gly Gly Thr Val Leu Leu Gln 
        35                  40                  45              


Ala Ala Asn Ser Tyr Leu Arg Asp Gln Trp Phe His Ser Leu Gln Trp 
    50                  55                  60                  


Lys Lys Lys Ile Tyr Lys Tyr Lys Lys Val Leu Ser Asn Pro Ser Arg 
65                  70                  75                  80  


Trp Glu Val Val Leu Lys Glu Ile Arg Thr Leu Val Asp Met Ala Leu 
                85                  90                  95      


Thr Ser Pro Leu Gln Asp Asp Ser Ile Asn Gln Ala Pro Leu Glu Ile 
            100                 105                 110         


Val Ser Lys Leu Leu Ser Glu Asn Thr Asn Leu Thr Thr Gln Glu His 
        115                 120                 125             


Glu Asn Ile Ile Val Ala Ile Ala Pro Leu Leu Glu Asn Asn His Pro 
    130                 135                 140                 


Pro Pro Asp Leu Cys Glu Phe Phe Cys Lys His Cys Arg Glu Arg Pro 
145                 150                 155                 160 


Arg Ser Met Val Val Ile Glu Val Phe Thr Pro Val Val Gln Arg Ile 
                165                 170                 175     


Leu Lys His Asn Met Asp Phe Gly Lys Cys Pro Arg Leu Arg Leu Phe 
            180                 185                 190         


Thr Gln Glu Tyr Ile Leu Ala Leu Asn Glu Leu Asn Ala Gly Met Glu 
        195                 200                 205             


Val Val Lys Lys Phe Ile Gln Ser Met His Gly Pro Thr Gly His Cys 
    210                 215                 220                 


Pro His Pro Arg Val Leu Pro Asn Leu Val Ala Val Cys Leu Ala Ala 
225                 230                 235                 240 


Ile Tyr Ser Cys Tyr Glu Glu Phe Ile Asn Ser Arg Asp Asn Ser Pro 
                245                 250                 255     


Ser Leu Lys Glu Ile Arg Asn Gly Cys Gln Gln Pro Cys Asp Arg Lys 
            260                 265                 270         


Pro Thr Leu Pro Leu Arg Leu Leu His Pro Ser Pro Asp Leu Val Ser 
        275                 280                 285             


Gln Glu Ala Thr Leu Ser Glu Ala Arg Leu Lys Ser Val Val Val Ala 
    290                 295                 300                 


Ser Ser Glu Ile His Val Glu Val Glu Arg Thr Ser Thr Ala Lys Pro 
305                 310                 315                 320 


Ala Leu Thr Ala Ser Ala Gly Asn Asp Ser Glu Pro Asn Leu Ile Asp 
                325                 330                 335     


Cys Leu Met Val Ser Pro Ala Cys Ser Thr Met Ser Ile Glu Leu Gly 
            340                 345                 350         


Pro Gln Ala Asp Arg Thr Leu Gly Cys Tyr Val Glu Ile Leu Lys Leu 
        355                 360                 365             


Leu Ser Asp Tyr Asp Asp Trp Arg Pro Ser Leu Ala Ser Leu Leu Gln 
    370                 375                 380                 


Pro Ile Pro Phe Pro Lys Glu Ala Leu Ala His Glu Lys Phe Thr Lys 
385                 390                 395                 400 


Glu Leu Lys Tyr Val Ile Gln Arg Phe Ala Glu Asp Pro Arg Gln Glu 
                405                 410                 415     


Val His Ser Cys Leu Leu Ser Val Arg Ala Gly Lys Asp Gly Trp Phe 
            420                 425                 430         


Gln Leu Tyr Ser Pro Gly Gly Val Ala Cys Asp Asp Asp Gly Glu Leu 
        435                 440                 445             


Phe Ala Ser Met Val His Ile Leu Met Gly Ser Cys Tyr Lys Thr Lys 
    450                 455                 460                 


Lys Phe Leu Leu Ser Leu Ala Glu Asn Lys Leu Gly Pro Cys Met Leu 
465                 470                 475                 480 


Leu Ala Leu Arg Gly Asn Gln Thr Met Val Glu Ile Leu Cys Leu Met 
                485                 490                 495     


Leu Glu Tyr Asn Ile Ile Asp Asn Asn Asp Thr Gln Leu Gln Ile Ile 
            500                 505                 510         


Ser Thr Leu Glu Ser Thr Asp Val Gly Lys Arg Met Tyr Glu Gln Leu 
        515                 520                 525             


Cys Asp Arg Gln Arg Glu Leu Lys Glu Leu Gln Arg Lys Gly Gly Pro 
    530                 535                 540                 


Thr Arg Leu Thr Leu Pro Ser Lys Ser Thr Asp Ala Asp Leu Ala Arg 
545                 550                 555                 560 


Leu Leu Ser Ser Gly Ser Phe Gly Asn Leu Glu Asn Leu Ser Leu Ala 
                565                 570                 575     


Phe Thr Asn Val Thr Ser Ala Cys Ala Glu His Leu Ile Lys Leu Pro 
            580                 585                 590         


Ser Leu Lys Gln Leu Asn Leu Trp Ser Thr Gln Phe Gly Asp Ala Gly 
        595                 600                 605             


Leu Arg Leu Leu Ser Glu His Leu Thr Met Leu Gln Val Leu Asn Leu 
    610                 615                 620                 


Cys Glu Thr Pro Val Thr Asp Ala Gly Leu Leu Ala Leu Ser Ser Met 
625                 630                 635                 640 


Lys Ser Leu Cys Ser Leu Asn Met Asn Ser Thr Lys Leu Ser Ala Asp 
                645                 650                 655     


Thr Tyr Glu Asp Leu Lys Ala Lys Leu Pro Asn Leu Lys Glu Val Asp 
            660                 665                 670         


Val Arg Tyr Thr Glu Ala Trp 
        675                 


<210>  3727
<211>  529
<212>  PRT
<213>  homo sapiens

<400>  3727

Met Asp Leu Pro Val Gly Pro Gly Ala Ala Gly Pro Ser Asn Val Pro 
1               5                   10                  15      


Ala Phe Leu Thr Lys Leu Trp Thr Leu Val Ser Asp Pro Asp Thr Asp 
            20                  25                  30          


Ala Leu Ile Cys Trp Ser Pro Ser Gly Asn Ser Phe His Val Phe Asp 
        35                  40                  45              


Gln Gly Gln Phe Ala Lys Glu Val Leu Pro Lys Tyr Phe Lys His Asn 
    50                  55                  60                  


Asn Met Ala Ser Phe Val Arg Gln Leu Asn Met Tyr Gly Phe Arg Lys 
65                  70                  75                  80  


Val Val His Ile Glu Gln Gly Gly Leu Val Lys Pro Glu Arg Asp Asp 
                85                  90                  95      


Thr Glu Phe Gln His Pro Cys Phe Leu Arg Gly Gln Glu Gln Leu Leu 
            100                 105                 110         


Glu Asn Ile Lys Arg Lys Val Thr Ser Val Ser Thr Leu Lys Ser Glu 
        115                 120                 125             


Asp Ile Lys Ile Arg Gln Asp Ser Val Thr Lys Leu Leu Thr Asp Val 
    130                 135                 140                 


Gln Leu Met Lys Gly Lys Gln Glu Cys Met Asp Ser Lys Leu Leu Ala 
145                 150                 155                 160 


Met Lys His Glu Asn Glu Ala Leu Trp Arg Glu Val Ala Ser Leu Arg 
                165                 170                 175     


Gln Lys His Ala Gln Gln Gln Lys Val Val Asn Lys Leu Ile Gln Phe 
            180                 185                 190         


Leu Ile Ser Leu Val Gln Ser Asn Arg Ile Leu Gly Val Lys Arg Lys 
        195                 200                 205             


Ile Pro Leu Met Leu Asn Asp Ser Gly Ser Ala His Ser Met Pro Lys 
    210                 215                 220                 


Tyr Ser Arg Gln Phe Ser Leu Glu His Val His Gly Ser Gly Pro Tyr 
225                 230                 235                 240 


Ser Ala Pro Ser Pro Ala Tyr Ser Ser Ser Ser Leu Tyr Ala Pro Asp 
                245                 250                 255     


Ala Val Ala Ser Ser Gly Pro Ile Ile Ser Asp Ile Thr Glu Leu Ala 
            260                 265                 270         


Pro Ala Ser Pro Met Ala Ser Pro Gly Gly Ser Ile Asp Glu Arg Pro 
        275                 280                 285             


Leu Ser Ser Ser Pro Leu Val Arg Val Lys Glu Glu Pro Pro Ser Pro 
    290                 295                 300                 


Pro Gln Ser Pro Arg Val Glu Glu Ala Ser Pro Gly Arg Pro Ser Ser 
305                 310                 315                 320 


Val Asp Thr Leu Leu Ser Pro Thr Ala Leu Ile Asp Ser Ile Leu Arg 
                325                 330                 335     


Glu Ser Glu Pro Ala Pro Ala Ser Val Thr Ala Leu Thr Asp Ala Arg 
            340                 345                 350         


Gly His Thr Asp Thr Glu Gly Arg Pro Pro Ser Pro Pro Pro Thr Ser 
        355                 360                 365             


Thr Pro Glu Lys Cys Leu Ser Val Ala Cys Leu Asp Lys Asn Glu Leu 
    370                 375                 380                 


Ser Asp His Leu Asp Ala Met Asp Ser Asn Leu Asp Asn Leu Gln Thr 
385                 390                 395                 400 


Met Leu Ser Ser His Gly Phe Ser Val Asp Thr Ser Ala Leu Leu Asp 
                405                 410                 415     


Leu Phe Ser Pro Ser Val Thr Val Pro Asp Met Ser Leu Pro Asp Leu 
            420                 425                 430         


Asp Ser Ser Leu Ala Ser Ile Gln Glu Leu Leu Ser Pro Gln Glu Pro 
        435                 440                 445             


Pro Arg Pro Pro Glu Ala Glu Asn Ser Ser Pro Asp Ser Gly Lys Gln 
    450                 455                 460                 


Leu Val His Tyr Thr Ala Gln Pro Leu Phe Leu Leu Asp Pro Gly Ser 
465                 470                 475                 480 


Val Asp Thr Gly Ser Asn Asp Leu Pro Val Leu Phe Glu Leu Gly Glu 
                485                 490                 495     


Gly Ser Tyr Phe Ser Glu Gly Asp Gly Phe Ala Glu Asp Pro Thr Ile 
            500                 505                 510         


Ser Leu Leu Thr Gly Ser Glu Pro Pro Lys Ala Lys Asp Pro Thr Val 
        515                 520                 525             


Ser 
    


<210>  3728
<211>  536
<212>  PRT
<213>  homo sapiens

<400>  3728

Met Lys Gln Ser Ser Asn Val Pro Ala Phe Leu Ser Lys Leu Trp Thr 
1               5                   10                  15      


Leu Val Glu Glu Thr His Thr Asn Glu Phe Ile Thr Trp Ser Gln Asn 
            20                  25                  30          


Gly Gln Ser Phe Leu Val Leu Asp Glu Gln Arg Phe Ala Lys Glu Ile 
        35                  40                  45              


Leu Pro Lys Tyr Phe Lys His Asn Asn Met Ala Ser Phe Val Arg Gln 
    50                  55                  60                  


Leu Asn Met Tyr Gly Phe Arg Lys Val Val His Ile Asp Ser Gly Ile 
65                  70                  75                  80  


Val Lys Gln Glu Arg Asp Gly Pro Val Glu Phe Gln His Pro Tyr Phe 
                85                  90                  95      


Lys Gln Gly Gln Asp Asp Leu Leu Glu Asn Ile Lys Arg Lys Val Ser 
            100                 105                 110         


Ser Ser Lys Pro Glu Glu Asn Lys Ile Arg Gln Glu Asp Leu Thr Lys 
        115                 120                 125             


Ile Ile Ser Ser Ala Gln Lys Val Gln Ile Lys Gln Glu Thr Ile Glu 
    130                 135                 140                 


Ser Arg Leu Ser Glu Leu Lys Ser Glu Asn Glu Ser Leu Trp Lys Glu 
145                 150                 155                 160 


Val Ser Glu Leu Arg Ala Lys His Ala Gln Gln Gln Gln Val Ile Arg 
                165                 170                 175     


Lys Ile Val Gln Phe Ile Val Thr Leu Val Gln Asn Asn Gln Leu Val 
            180                 185                 190         


Ser Leu Lys Arg Lys Arg Pro Leu Leu Leu Asn Thr Asn Gly Ala Gln 
        195                 200                 205             


Lys Lys Asn Leu Phe Gln His Ile Val Lys Glu Pro Thr Asp Asn His 
    210                 215                 220                 


His His Lys Val Pro His Ser Arg Thr Glu Gly Leu Lys Pro Arg Glu 
225                 230                 235                 240 


Arg Ile Ser Asp Asp Ile Ile Ile Tyr Asp Val Thr Asp Asp Asn Ala 
                245                 250                 255     


Asp Glu Glu Asn Ile Pro Val Ile Pro Glu Thr Asn Glu Asp Val Ile 
            260                 265                 270         


Ser Asp Pro Ser Asn Cys Ser Gln Tyr Pro Asp Ile Val Ile Val Glu 
        275                 280                 285             


Asp Asp Asn Glu Asp Glu Tyr Ala Pro Val Ile Gln Ser Gly Glu Gln 
    290                 295                 300                 


Asn Glu Pro Ala Arg Glu Ser Leu Ser Ser Gly Ser Asp Gly Ser Ser 
305                 310                 315                 320 


Pro Leu Met Ser Ser Ala Val Gln Leu Asn Gly Ser Ser Ser Leu Thr 
                325                 330                 335     


Ser Glu Asp Pro Val Thr Met Met Asp Ser Ile Leu Asn Asp Asn Ile 
            340                 345                 350         


Asn Leu Leu Gly Lys Val Glu Leu Leu Asp Tyr Leu Asp Ser Ile Asp 
        355                 360                 365             


Cys Ser Leu Glu Asp Phe Gln Ala Met Leu Ser Gly Arg Gln Phe Ser 
    370                 375                 380                 


Ile Asp Pro Asp Leu Leu Val Asp Leu Phe Thr Ser Ser Val Gln Met 
385                 390                 395                 400 


Asn Pro Thr Asp Tyr Ile Asn Asn Thr Lys Ser Glu Asn Lys Gly Leu 
                405                 410                 415     


Glu Thr Thr Lys Asn Asn Val Val Gln Pro Val Ser Glu Glu Gly Arg 
            420                 425                 430         


Lys Ser Lys Ser Lys Pro Asp Lys Gln Leu Ile Gln Tyr Thr Ala Phe 
        435                 440                 445             


Pro Leu Leu Ala Phe Leu Asp Gly Asn Pro Ala Ser Ser Val Glu Gln 
    450                 455                 460                 


Ala Ser Thr Thr Ala Ser Ser Glu Val Leu Ser Ser Val Asp Lys Pro 
465                 470                 475                 480 


Ile Glu Val Asp Glu Leu Leu Asp Ser Ser Leu Asp Pro Glu Pro Thr 
                485                 490                 495     


Gln Ser Lys Leu Val Arg Leu Glu Pro Leu Thr Glu Ala Glu Ala Ser 
            500                 505                 510         


Glu Ala Thr Leu Phe Tyr Leu Cys Glu Leu Ala Pro Ala Pro Leu Asp 
        515                 520                 525             


Ser Asp Met Pro Leu Leu Asp Ser 
    530                 535     


<210>  3729
<211>  518
<212>  PRT
<213>  homo sapiens

<400>  3729

Met Lys Gln Ser Ser Asn Val Pro Ala Phe Leu Ser Lys Leu Trp Thr 
1               5                   10                  15      


Leu Val Glu Glu Thr His Thr Asn Glu Phe Ile Thr Trp Ser Gln Asn 
            20                  25                  30          


Gly Gln Ser Phe Leu Val Leu Asp Glu Gln Arg Phe Ala Lys Glu Ile 
        35                  40                  45              


Leu Pro Lys Tyr Phe Lys His Asn Asn Met Ala Ser Phe Val Arg Gln 
    50                  55                  60                  


Leu Asn Met Tyr Gly Phe Arg Lys Val Val His Ile Asp Ser Gly Ile 
65                  70                  75                  80  


Val Lys Gln Glu Arg Asp Gly Pro Val Glu Phe Gln His Pro Tyr Phe 
                85                  90                  95      


Lys Gln Gly Gln Asp Asp Leu Leu Glu Asn Ile Lys Arg Lys Val Ser 
            100                 105                 110         


Ser Ser Lys Pro Glu Glu Asn Lys Ile Arg Gln Glu Asp Leu Thr Lys 
        115                 120                 125             


Ile Ile Ser Ser Ala Gln Lys Val Gln Ile Lys Gln Glu Thr Ile Glu 
    130                 135                 140                 


Ser Arg Leu Ser Glu Leu Lys Ser Glu Asn Glu Ser Leu Trp Lys Glu 
145                 150                 155                 160 


Val Ser Glu Leu Arg Ala Lys His Ala Gln Gln Gln Gln Val Ile Arg 
                165                 170                 175     


Lys Ile Val Gln Phe Ile Val Thr Leu Val Gln Asn Asn Gln Leu Val 
            180                 185                 190         


Ser Leu Lys Arg Lys Arg Pro Leu Leu Leu Asn Thr Asn Gly Ala Gln 
        195                 200                 205             


Lys Lys Asn Leu Phe Gln His Ile Val Lys Glu Pro Thr Asp Asn His 
    210                 215                 220                 


His His Lys Val Pro His Ser Arg Thr Glu Gly Leu Lys Pro Arg Glu 
225                 230                 235                 240 


Arg Ile Ser Asp Asp Ile Ile Ile Tyr Asp Val Thr Asp Asp Asn Ala 
                245                 250                 255     


Asp Glu Glu Asn Ile Pro Val Ile Pro Glu Thr Asn Glu Asp Val Ile 
            260                 265                 270         


Ser Asp Pro Ser Asn Cys Ser Gln Tyr Pro Asp Ile Val Ile Val Glu 
        275                 280                 285             


Asp Asp Asn Glu Asp Glu Tyr Ala Pro Val Ile Gln Ser Gly Glu Gln 
    290                 295                 300                 


Asn Glu Pro Ala Arg Glu Ser Leu Ser Ser Gly Ser Asp Gly Ser Ser 
305                 310                 315                 320 


Pro Leu Met Ser Ser Ala Val Gln Leu Asn Gly Ser Ser Ser Leu Thr 
                325                 330                 335     


Ser Glu Asp Pro Val Thr Met Met Asp Ser Ile Leu Asn Asp Asn Ile 
            340                 345                 350         


Asn Leu Leu Gly Lys Val Glu Leu Leu Asp Tyr Leu Asp Ser Ile Asp 
        355                 360                 365             


Cys Ser Leu Glu Asp Phe Gln Ala Met Leu Ser Gly Arg Gln Phe Ser 
    370                 375                 380                 


Ile Asp Pro Asp Leu Leu Val Asp Ser Glu Asn Lys Gly Leu Glu Thr 
385                 390                 395                 400 


Thr Lys Asn Asn Val Val Gln Pro Val Ser Glu Glu Gly Arg Lys Ser 
                405                 410                 415     


Lys Ser Lys Pro Asp Lys Gln Leu Ile Gln Tyr Thr Ala Phe Pro Leu 
            420                 425                 430         


Leu Ala Phe Leu Asp Gly Asn Pro Ala Ser Ser Val Glu Gln Ala Ser 
        435                 440                 445             


Thr Thr Ala Ser Ser Glu Val Leu Ser Ser Val Asp Lys Pro Ile Glu 
    450                 455                 460                 


Val Asp Glu Leu Leu Asp Ser Ser Leu Asp Pro Glu Pro Thr Gln Ser 
465                 470                 475                 480 


Lys Leu Val Arg Leu Glu Pro Leu Thr Glu Ala Glu Ala Ser Glu Ala 
                485                 490                 495     


Thr Leu Phe Tyr Leu Cys Glu Leu Ala Pro Ala Pro Leu Asp Ser Asp 
            500                 505                 510         


Met Pro Leu Leu Asp Ser 
        515             


<210>  3730
<211>  480
<212>  PRT
<213>  homo sapiens

<400>  3730

Met Gln Ile Pro Arg Ala Ala Leu Leu Pro Leu Leu Leu Leu Leu Leu 
1               5                   10                  15      


Ala Ala Pro Ala Ser Ala Gln Leu Ser Arg Ala Gly Arg Ser Ala Pro 
            20                  25                  30          


Leu Ala Ala Gly Cys Pro Asp Arg Cys Glu Pro Ala Arg Cys Pro Pro 
        35                  40                  45              


Gln Pro Glu His Cys Glu Gly Gly Arg Ala Arg Asp Ala Cys Gly Cys 
    50                  55                  60                  


Cys Glu Val Cys Gly Ala Pro Glu Gly Ala Ala Cys Gly Leu Gln Glu 
65                  70                  75                  80  


Gly Pro Cys Gly Glu Gly Leu Gln Cys Val Val Pro Phe Gly Val Pro 
                85                  90                  95      


Ala Ser Ala Thr Val Arg Arg Arg Ala Gln Ala Gly Leu Cys Val Cys 
            100                 105                 110         


Ala Ser Ser Glu Pro Val Cys Gly Ser Asp Ala Asn Thr Tyr Ala Asn 
        115                 120                 125             


Leu Cys Gln Leu Arg Ala Ala Ser Arg Arg Ser Glu Arg Leu His Arg 
    130                 135                 140                 


Pro Pro Val Ile Val Leu Gln Arg Gly Ala Cys Gly Gln Gly Gln Glu 
145                 150                 155                 160 


Asp Pro Asn Ser Leu Arg His Lys Tyr Asn Phe Ile Ala Asp Val Val 
                165                 170                 175     


Glu Lys Ile Ala Pro Ala Val Val His Ile Glu Leu Phe Arg Lys Leu 
            180                 185                 190         


Pro Phe Ser Lys Arg Glu Val Pro Val Ala Ser Gly Ser Gly Phe Ile 
        195                 200                 205             


Val Ser Glu Asp Gly Leu Ile Val Thr Asn Ala His Val Val Thr Asn 
    210                 215                 220                 


Lys His Arg Val Lys Val Glu Leu Lys Asn Gly Ala Thr Tyr Glu Ala 
225                 230                 235                 240 


Lys Ile Lys Asp Val Asp Glu Lys Ala Asp Ile Ala Leu Ile Lys Ile 
                245                 250                 255     


Asp His Gln Gly Lys Leu Pro Val Leu Leu Leu Gly Arg Ser Ser Glu 
            260                 265                 270         


Leu Arg Pro Gly Glu Phe Val Val Ala Ile Gly Ser Pro Phe Ser Leu 
        275                 280                 285             


Gln Asn Thr Val Thr Thr Gly Ile Val Ser Thr Thr Gln Arg Gly Gly 
    290                 295                 300                 


Lys Glu Leu Gly Leu Arg Asn Ser Asp Met Asp Tyr Ile Gln Thr Asp 
305                 310                 315                 320 


Ala Ile Ile Asn Tyr Gly Asn Ser Gly Gly Pro Leu Val Asn Leu Asp 
                325                 330                 335     


Gly Glu Val Ile Gly Ile Asn Thr Leu Lys Val Thr Ala Gly Ile Ser 
            340                 345                 350         


Phe Ala Ile Pro Ser Asp Lys Ile Lys Lys Phe Leu Thr Glu Ser His 
        355                 360                 365             


Asp Arg Gln Ala Lys Gly Lys Ala Ile Thr Lys Lys Lys Tyr Ile Gly 
    370                 375                 380                 


Ile Arg Met Met Ser Leu Thr Ser Ser Lys Ala Lys Glu Leu Lys Asp 
385                 390                 395                 400 


Arg His Arg Asp Phe Pro Asp Val Ile Ser Gly Ala Tyr Ile Ile Glu 
                405                 410                 415     


Val Ile Pro Asp Thr Pro Ala Glu Ala Gly Gly Leu Lys Glu Asn Asp 
            420                 425                 430         


Val Ile Ile Ser Ile Asn Gly Gln Ser Val Val Ser Ala Asn Asp Val 
        435                 440                 445             


Ser Asp Val Ile Lys Arg Glu Ser Thr Leu Asn Met Val Val Arg Arg 
    450                 455                 460                 


Gly Asn Glu Asp Ile Met Ile Thr Val Ile Pro Glu Glu Ile Asp Pro 
465                 470                 475                 480 


<210>  3731
<211>  248
<212>  PRT
<213>  homo sapiens

<400>  3731

Met Ala Leu Cys Glu Ala Ala Gly Cys Gly Ser Ala Leu Leu Trp Pro 
1               5                   10                  15      


Arg Leu Leu Leu Phe Gly Asp Ser Ile Thr Gln Phe Ser Phe Gln Gln 
            20                  25                  30          


Gly Gly Trp Gly Ala Ser Leu Ala Asp Arg Leu Val Arg Lys Cys Asp 
        35                  40                  45              


Val Leu Asn Arg Gly Phe Ser Gly Tyr Asn Thr Arg Trp Ala Lys Ile 
    50                  55                  60                  


Ile Leu Pro Arg Leu Ile Arg Lys Gly Asn Ser Leu Asp Ile Pro Val 
65                  70                  75                  80  


Ala Val Thr Ile Phe Phe Gly Ala Asn Asp Ser Ala Leu Lys Asp Glu 
                85                  90                  95      


Asn Pro Lys Gln His Ile Pro Leu Glu Glu Tyr Ala Ala Asn Leu Lys 
            100                 105                 110         


Ser Met Val Gln Tyr Leu Lys Ser Val Asp Ile Pro Glu Asn Arg Val 
        115                 120                 125             


Ile Leu Ile Thr Pro Thr Pro Leu Cys Glu Thr Ala Trp Glu Glu Gln 
    130                 135                 140                 


Cys Ile Ile Gln Gly Cys Lys Leu Asn Arg Leu Asn Ser Val Val Gly 
145                 150                 155                 160 


Glu Tyr Ala Asn Ala Cys Leu Gln Val Ala Gln Asp Cys Gly Thr Asp 
                165                 170                 175     


Val Leu Asp Leu Trp Thr Leu Met Gln Asp Ser Gln Asp Phe Ser Ser 
            180                 185                 190         


Tyr Leu Ser Asp Gly Leu His Leu Ser Pro Lys Gly Asn Glu Phe Leu 
        195                 200                 205             


Phe Ser His Leu Trp Pro Leu Ile Glu Lys Lys Val Ser Ser Leu Pro 
    210                 215                 220                 


Leu Leu Leu Pro Tyr Trp Arg Asp Val Ala Glu Ala Lys Pro Glu Leu 
225                 230                 235                 240 


Ser Leu Leu Gly Asp Gly Asp His 
                245             


<210>  3732
<211>  625
<212>  PRT
<213>  homo sapiens

<400>  3732

Met Ala Lys Lys Ser Ala Glu Asn Gly Ile Tyr Ser Val Ser Gly Asp 
1               5                   10                  15      


Glu Lys Lys Gly Pro Leu Ile Ala Pro Gly Pro Asp Gly Ala Pro Ala 
            20                  25                  30          


Lys Gly Asp Gly Pro Val Gly Leu Gly Thr Pro Gly Gly Arg Leu Ala 
        35                  40                  45              


Val Pro Pro Arg Glu Thr Trp Thr Arg Gln Met Asp Phe Ile Met Ser 
    50                  55                  60                  


Cys Val Gly Phe Ala Val Gly Leu Gly Asn Val Trp Arg Phe Pro Tyr 
65                  70                  75                  80  


Leu Cys Tyr Lys Asn Gly Gly Gly Val Phe Leu Ile Pro Tyr Val Leu 
                85                  90                  95      


Ile Ala Leu Val Gly Gly Ile Pro Ile Phe Phe Leu Glu Ile Ser Leu 
            100                 105                 110         


Gly Gln Phe Met Lys Ala Gly Ser Ile Asn Val Trp Asn Ile Cys Pro 
        115                 120                 125             


Leu Phe Lys Gly Leu Gly Tyr Ala Ser Met Val Ile Val Phe Tyr Cys 
    130                 135                 140                 


Asn Thr Tyr Tyr Ile Met Val Leu Ala Trp Gly Phe Tyr Tyr Leu Val 
145                 150                 155                 160 


Lys Ser Phe Thr Thr Thr Leu Pro Trp Ala Thr Cys Gly His Thr Trp 
                165                 170                 175     


Asn Thr Pro Asp Cys Val Glu Ile Phe Arg His Glu Asp Cys Ala Asn 
            180                 185                 190         


Ala Ser Leu Ala Asn Leu Thr Cys Asp Gln Leu Ala Asp Arg Arg Ser 
        195                 200                 205             


Pro Val Ile Glu Phe Trp Glu Asn Lys Val Leu Arg Leu Ser Gly Gly 
    210                 215                 220                 


Leu Glu Val Pro Gly Ala Leu Asn Trp Glu Val Thr Leu Cys Leu Leu 
225                 230                 235                 240 


Ala Cys Trp Val Leu Val Tyr Phe Cys Val Trp Lys Gly Val Lys Ser 
                245                 250                 255     


Thr Gly Lys Ile Val Tyr Phe Thr Ala Thr Phe Pro Tyr Val Val Leu 
            260                 265                 270         


Val Val Leu Leu Val Arg Gly Val Leu Leu Pro Gly Ala Leu Asp Gly 
        275                 280                 285             


Ile Ile Tyr Tyr Leu Lys Pro Asp Trp Ser Lys Leu Gly Ser Pro Gln 
    290                 295                 300                 


Val Trp Ile Asp Ala Gly Thr Gln Ile Phe Phe Ser Tyr Ala Ile Gly 
305                 310                 315                 320 


Leu Gly Ala Leu Thr Ala Leu Gly Ser Tyr Asn Arg Phe Asn Asn Asn 
                325                 330                 335     


Cys Tyr Asn Gly Thr Ser Phe Phe Ala Gly Phe Val Val Phe Ser Ile 
            340                 345                 350         


Leu Gly Phe Met Ala Ala Glu Gln Gly Val His Ile Ser Lys Val Ala 
        355                 360                 365             


Glu Ser Gly Pro Gly Leu Ala Phe Ile Ala Tyr Pro Arg Ala Val Thr 
    370                 375                 380                 


Leu Met Pro Val Ala Pro Leu Trp Ala Ala Leu Phe Phe Phe Met Leu 
385                 390                 395                 400 


Leu Leu Leu Gly Leu Asp Ser Gln Phe Val Gly Val Glu Gly Phe Ile 
                405                 410                 415     


Thr Gly Leu Leu Asp Leu Leu Pro Ala Ser Tyr Tyr Phe Arg Phe Gln 
            420                 425                 430         


Arg Glu Ile Ser Val Ala Leu Cys Cys Ala Leu Cys Phe Val Ile Asp 
        435                 440                 445             


Leu Ser Met Val Thr Asp Gly Gly Met Tyr Val Phe Gln Leu Phe Asp 
    450                 455                 460                 


Tyr Tyr Ser Ala Ser Gly Thr Thr Leu Leu Trp Gln Ala Phe Trp Glu 
465                 470                 475                 480 


Cys Val Val Val Ala Trp Val Tyr Gly Ala Asp Arg Phe Met Asp Asp 
                485                 490                 495     


Ile Ala Cys Met Ile Gly Tyr Arg Pro Cys Pro Trp Met Lys Trp Cys 
            500                 505                 510         


Trp Ser Phe Phe Thr Pro Leu Val Cys Met Gly Ile Phe Ile Phe Asn 
        515                 520                 525             


Val Val Tyr Tyr Glu Pro Leu Val Tyr Asn Asn Thr Tyr Val Tyr Pro 
    530                 535                 540                 


Trp Trp Gly Glu Ala Met Gly Trp Ala Phe Ala Leu Ser Ser Met Leu 
545                 550                 555                 560 


Cys Val Pro Leu His Leu Leu Gly Cys Leu Leu Arg Ala Lys Gly Thr 
                565                 570                 575     


Met Ala Glu Arg Trp Gln His Leu Thr Gln Pro Ile Trp Gly Leu His 
            580                 585                 590         


His Leu Glu Tyr Arg Ala Gln Asp Ala Asp Val Arg Gly Leu Thr Thr 
        595                 600                 605             


Leu Thr Pro Val Ser Glu Ser Ser Lys Val Val Val Val Glu Ser Val 
    610                 615                 620                 


Met 
625 


<210>  3733
<211>  203
<212>  PRT
<213>  homo sapiens

<400>  3733

Met Ala Glu Gly Asp Asn Arg Ser Thr Asn Leu Leu Ala Ala Glu Thr 
1               5                   10                  15      


Ala Ser Leu Glu Glu Gln Leu Gln Gly Trp Gly Glu Val Met Leu Met 
            20                  25                  30          


Ala Asp Lys Val Leu Arg Trp Glu Arg Ala Trp Phe Pro Pro Ala Ile 
        35                  40                  45              


Met Gly Val Val Ser Leu Val Phe Leu Ile Ile Tyr Tyr Leu Asp Pro 
    50                  55                  60                  


Ser Val Leu Ser Gly Val Ser Cys Phe Val Met Phe Leu Cys Leu Ala 
65                  70                  75                  80  


Asp Tyr Leu Val Pro Ile Leu Ala Pro Arg Ile Phe Gly Ser Asn Lys 
                85                  90                  95      


Trp Thr Thr Glu Gln Gln Gln Arg Phe His Glu Ile Cys Ser Asn Leu 
            100                 105                 110         


Val Lys Thr Arg Arg Arg Ala Val Gly Trp Trp Lys Arg Leu Phe Thr 
        115                 120                 125             


Leu Lys Glu Glu Lys Pro Lys Met Tyr Phe Met Thr Met Ile Val Ser 
    130                 135                 140                 


Leu Ala Ala Val Ala Trp Val Gly Gln Gln Val His Asn Leu Leu Leu 
145                 150                 155                 160 


Thr Tyr Leu Ile Val Thr Ser Leu Leu Leu Leu Pro Gly Leu Asn Gln 
                165                 170                 175     


His Gly Ile Ile Leu Lys Tyr Ile Gly Met Ala Lys Arg Glu Ile Asn 
            180                 185                 190         


Lys Leu Leu Lys Gln Lys Glu Lys Lys Asn Glu 
        195                 200             


<210>  3734
<211>  1849
<212>  PRT
<213>  homo sapiens

<400>  3734

Met Ala Val Ser Arg Leu Asp Arg Leu Phe Ile Leu Leu Asp Thr Gly 
1               5                   10                  15      


Thr Thr Pro Val Thr Arg Lys Ala Ala Ala Gln Gln Leu Gly Glu Val 
            20                  25                  30          


Val Lys Leu His Pro His Glu Leu Asn Asn Leu Leu Ser Lys Val Leu 
        35                  40                  45              


Ile Tyr Leu Arg Ser Ala Asn Trp Asp Thr Arg Ile Ala Ala Gly Gln 
    50                  55                  60                  


Ala Val Glu Ala Ile Val Lys Asn Val Pro Glu Trp Asn Pro Val Pro 
65                  70                  75                  80  


Arg Thr Arg Gln Glu Pro Thr Ser Glu Ser Ser Met Glu Asp Ser Pro 
                85                  90                  95      


Thr Thr Glu Arg Leu Asn Phe Asp Arg Phe Asp Ile Cys Arg Leu Leu 
            100                 105                 110         


Gln His Gly Ala Ser Leu Leu Gly Ser Ala Gly Ala Glu Phe Glu Val 
        115                 120                 125             


Gln Asp Glu Lys Ser Gly Glu Val Asp Pro Lys Glu Arg Ile Ala Arg 
    130                 135                 140                 


Gln Arg Lys Leu Leu Gln Lys Lys Leu Gly Leu Asn Met Gly Glu Ala 
145                 150                 155                 160 


Ile Gly Met Ser Thr Glu Glu Leu Phe Asn Asp Glu Asp Leu Asp Tyr 
                165                 170                 175     


Thr Pro Thr Ser Ala Ser Phe Val Asn Lys Gln Pro Thr Leu Gln Ala 
            180                 185                 190         


Ala Glu Leu Ile Asp Ser Glu Phe Arg Ala Gly Met Ser Asn Arg Gln 
        195                 200                 205             


Lys Asn Lys Ala Lys Arg Met Ala Lys Leu Phe Ala Lys Gln Arg Ser 
    210                 215                 220                 


Arg Asp Ala Val Glu Thr Asn Glu Lys Ser Asn Asp Ser Thr Asp Gly 
225                 230                 235                 240 


Glu Pro Glu Glu Lys Arg Arg Lys Ile Ala Asn Val Val Ile Asn Gln 
                245                 250                 255     


Ser Ala Asn Asp Ser Lys Val Leu Ile Asp Asn Ile Pro Asp Ser Ser 
            260                 265                 270         


Ser Leu Ile Glu Glu Thr Asn Glu Trp Pro Leu Glu Ser Phe Cys Glu 
        275                 280                 285             


Glu Leu Cys Asn Asp Leu Phe Asn Pro Ser Trp Glu Val Arg His Gly 
    290                 295                 300                 


Ala Gly Thr Gly Leu Arg Glu Ile Leu Lys Ala His Gly Lys Ser Gly 
305                 310                 315                 320 


Gly Lys Met Gly Asp Ser Thr Leu Glu Glu Met Ile Gln Gln His Gln 
                325                 330                 335     


Glu Trp Leu Glu Asp Leu Val Ile Arg Leu Leu Cys Val Phe Ala Leu 
            340                 345                 350         


Asp Arg Phe Gly Asp Phe Val Ser Asp Glu Val Val Ala Pro Val Arg 
        355                 360                 365             


Glu Thr Cys Ala Gln Thr Leu Gly Val Val Leu Lys His Met Asn Glu 
    370                 375                 380                 


Thr Gly Val His Lys Thr Val Asp Val Leu Leu Lys Leu Leu Thr Gln 
385                 390                 395                 400 


Glu Gln Trp Glu Val Arg His Gly Gly Leu Leu Gly Ile Lys Tyr Ala 
                405                 410                 415     


Leu Ala Val Arg Gln Asp Val Ile Asn Thr Leu Leu Pro Lys Val Leu 
            420                 425                 430         


Thr Arg Ile Ile Glu Gly Leu Gln Asp Leu Asp Asp Asp Val Arg Ala 
        435                 440                 445             


Val Ala Ala Ala Ser Leu Val Pro Val Val Glu Ser Leu Val Tyr Leu 
    450                 455                 460                 


Gln Thr Gln Lys Val Pro Phe Ile Ile Asn Thr Leu Trp Asp Ala Leu 
465                 470                 475                 480 


Leu Glu Leu Asp Asp Leu Thr Ala Ser Thr Asn Ser Ile Met Thr Leu 
                485                 490                 495     


Leu Ser Ser Leu Leu Thr Tyr Pro Gln Val Gln Gln Cys Ser Ile Gln 
            500                 505                 510         


Gln Ser Leu Thr Val Leu Val Pro Arg Val Trp Pro Phe Leu His His 
        515                 520                 525             


Thr Ile Ser Ser Val Arg Arg Ala Ala Leu Glu Thr Leu Phe Thr Leu 
    530                 535                 540                 


Leu Ser Thr Gln Asp Gln Asn Ser Ser Ser Trp Leu Ile Pro Ile Leu 
545                 550                 555                 560 


Pro Asp Met Leu Arg His Ile Phe Gln Phe Cys Val Leu Glu Ser Ser 
                565                 570                 575     


Gln Glu Ile Leu Asp Leu Ile His Lys Val Trp Met Glu Leu Leu Ser 
            580                 585                 590         


Lys Ala Ser Val Gln Tyr Val Val Ala Ala Ala Cys Pro Trp Met Gly 
        595                 600                 605             


Ala Trp Leu Cys Leu Met Met Gln Pro Ser His Leu Pro Ile Asp Leu 
    610                 615                 620                 


Asn Met Leu Leu Glu Val Lys Ala Arg Ala Lys Glu Lys Thr Gly Gly 
625                 630                 635                 640 


Lys Val Arg Gln Gly Gln Ser Gln Asn Lys Glu Val Leu Gln Glu Tyr 
                645                 650                 655     


Ile Ala Gly Ala Asp Thr Ile Met Glu Asp Pro Ala Thr Arg Asp Phe 
            660                 665                 670         


Val Val Met Arg Ala Arg Met Met Ala Ala Lys Leu Leu Gly Ala Leu 
        675                 680                 685             


Cys Cys Cys Ile Cys Asp Pro Gly Val Asn Val Val Thr Gln Glu Ile 
    690                 695                 700                 


Lys Pro Ala Glu Ser Leu Gly Gln Leu Leu Leu Phe His Leu Asn Ser 
705                 710                 715                 720 


Lys Ser Ala Leu Gln Arg Ile Ser Val Ala Leu Val Ile Cys Glu Trp 
                725                 730                 735     


Ala Ala Leu Gln Lys Glu Cys Lys Ala Val Thr Leu Ala Val Gln Pro 
            740                 745                 750         


Arg Leu Leu Asp Ile Leu Ser Glu His Leu Tyr Tyr Asp Glu Ile Ala 
        755                 760                 765             


Val Pro Phe Thr Arg Met Gln Asn Glu Cys Lys Gln Leu Ile Ser Ser 
    770                 775                 780                 


Leu Ala Asp Val His Ile Glu Val Gly Asn Arg Val Asn Asn Asn Val 
785                 790                 795                 800 


Leu Thr Ile Asp Gln Ala Ser Asp Leu Val Thr Thr Val Phe Asn Glu 
                805                 810                 815     


Ala Thr Ser Ser Phe Asp Leu Asn Pro Gln Val Leu Gln Gln Leu Asp 
            820                 825                 830         


Ser Lys Arg Gln Gln Val Gln Met Thr Val Thr Glu Thr Asn Gln Glu 
        835                 840                 845             


Trp Gln Val Leu Gln Leu Arg Val His Thr Phe Ala Ala Cys Ala Val 
    850                 855                 860                 


Val Ser Leu Gln Gln Leu Pro Glu Lys Leu Asn Pro Ile Ile Lys Pro 
865                 870                 875                 880 


Leu Met Glu Thr Ile Lys Lys Glu Glu Asn Thr Leu Val Gln Asn Tyr 
                885                 890                 895     


Ala Ala Gln Cys Ile Ala Lys Leu Leu Gln Gln Cys Thr Thr Arg Thr 
            900                 905                 910         


Pro Cys Pro Asn Ser Lys Ile Ile Lys Asn Leu Cys Ser Ser Leu Cys 
        915                 920                 925             


Val Asp Pro Tyr Leu Thr Pro Cys Val Thr Cys Pro Val Pro Thr Gln 
    930                 935                 940                 


Ser Gly Gln Glu Asn Ser Lys Gly Ser Thr Ser Glu Lys Asp Gly Met 
945                 950                 955                 960 


His His Thr Val Thr Lys His Arg Gly Ile Ile Thr Leu Tyr Arg His 
                965                 970                 975     


Gln Lys Ala Ala Phe Ala Ile Thr Ser Arg Arg Gly Pro Thr Pro Lys 
            980                 985                 990         


Ala Val Lys Ala Gln Ile Ala Asp  Leu Pro Ala Gly Ser  Ser Gly Asn 
        995                 1000                 1005             


Ile Leu  Val Glu Leu Asp Glu  Ala Gln Lys Pro Tyr  Leu Val Gln 
    1010                 1015                 1020             


Arg Arg  Gly Ala Glu Phe Ala  Leu Thr Thr Ile Val  Lys His Phe 
    1025                 1030                 1035             


Gly Gly  Glu Met Ala Val Lys  Leu Pro His Leu Trp  Asp Ala Met 
    1040                 1045                 1050             


Val Gly  Pro Leu Arg Asn Thr  Ile Asp Ile Asn Asn  Phe Asp Gly 
    1055                 1060                 1065             


Lys Ser  Leu Leu Asp Lys Gly  Asp Ser Pro Ala Gln  Glu Leu Val 
    1070                 1075                 1080             


Asn Ser  Leu Gln Val Phe Glu  Thr Ala Ala Ala Ser  Met Asp Ser 
    1085                 1090                 1095             


Glu Leu  His Pro Leu Leu Val  Gln His Leu Pro His  Leu Tyr Met 
    1100                 1105                 1110             


Cys Leu  Gln Tyr Pro Ser Thr  Ala Val Arg His Met  Ala Ala Arg 
    1115                 1120                 1125             


Cys Val  Gly Val Met Ser Lys  Ile Ala Thr Met Glu  Thr Met Asn 
    1130                 1135                 1140             


Ile Phe  Leu Glu Lys Val Leu  Pro Trp Leu Gly Ala  Ile Asp Asp 
    1145                 1150                 1155             


Ser Val  Lys Gln Glu Gly Ala  Ile Glu Ala Leu Ala  Cys Val Met 
    1160                 1165                 1170             


Glu Gln  Leu Asp Val Gly Ile  Val Pro Tyr Ile Val  Leu Leu Val 
    1175                 1180                 1185             


Val Pro  Val Leu Gly Arg Met  Ser Asp Gln Thr Asp  Ser Val Arg 
    1190                 1195                 1200             


Phe Met  Ala Thr Gln Cys Phe  Ala Thr Leu Ile Arg  Leu Met Pro 
    1205                 1210                 1215             


Leu Glu  Ala Gly Ile Pro Asp  Pro Pro Asn Met Ser  Ala Glu Leu 
    1220                 1225                 1230             


Ile Gln  Leu Lys Ala Lys Glu  Arg His Phe Leu Glu  Gln Leu Leu 
    1235                 1240                 1245             


Asp Gly  Lys Lys Leu Glu Asn  Tyr Lys Ile Pro Val  Pro Ile Asn 
    1250                 1255                 1260             


Ala Glu  Leu Arg Lys Tyr Gln  Gln Asp Gly Val Asn  Trp Leu Ala 
    1265                 1270                 1275             


Phe Leu  Asn Lys Tyr Lys Leu  His Gly Ile Leu Cys  Asp Asp Met 
    1280                 1285                 1290             


Gly Leu  Gly Lys Thr Leu Gln  Ser Ile Cys Ile Leu  Ala Gly Asp 
    1295                 1300                 1305             


His Cys  His Arg Ala Gln Glu  Tyr Ala Arg Ser Lys  Leu Ala Glu 
    1310                 1315                 1320             


Cys Met  Pro Leu Pro Ser Leu  Val Val Cys Pro Pro  Thr Leu Thr 
    1325                 1330                 1335             


Gly His  Trp Val Asp Glu Val  Gly Lys Phe Cys Ser  Arg Glu Tyr 
    1340                 1345                 1350             


Leu Asn  Pro Leu His Tyr Thr  Gly Pro Pro Thr Glu  Arg Ile Arg 
    1355                 1360                 1365             


Leu Gln  His Gln Val Lys Arg  His Asn Leu Ile Val  Ala Ser Tyr 
    1370                 1375                 1380             


Asp Val  Val Arg Asn Asp Ile  Asp Phe Phe Arg Asn  Ile Lys Phe 
    1385                 1390                 1395             


Asn Tyr  Cys Ile Leu Asp Glu  Gly His Val Ile Lys  Asn Gly Lys 
    1400                 1405                 1410             


Thr Lys  Leu Ser Lys Ala Val  Lys Gln Leu Thr Ala  Asn Tyr Arg 
    1415                 1420                 1425             


Ile Ile  Leu Ser Gly Thr Pro  Ile Gln Asn Asn Val  Leu Glu Leu 
    1430                 1435                 1440             


Trp Ser  Leu Phe Asp Phe Leu  Met Pro Gly Phe Leu  Gly Thr Glu 
    1445                 1450                 1455             


Arg Gln  Phe Ala Ala Arg Tyr  Gly Lys Pro Ile Leu  Ala Ser Arg 
    1460                 1465                 1470             


Asp Ala  Arg Ser Ser Ser Arg  Glu Gln Glu Ala Gly  Val Leu Ala 
    1475                 1480                 1485             


Met Asp  Ala Leu His Arg Gln  Val Leu Pro Phe Leu  Leu Arg Arg 
    1490                 1495                 1500             


Met Lys  Glu Asp Val Leu Gln  Asp Leu Pro Pro Lys  Ile Ile Gln 
    1505                 1510                 1515             


Asp Tyr  Tyr Cys Thr Leu Ser  Pro Leu Gln Val Gln  Leu Tyr Glu 
    1520                 1525                 1530             


Asp Phe  Ala Lys Ser Arg Ala  Lys Cys Asp Val Asp  Glu Thr Val 
    1535                 1540                 1545             


Ser Ser  Ala Thr Leu Ser Glu  Glu Thr Glu Lys Pro  Lys Leu Lys 
    1550                 1555                 1560             


Ala Thr  Gly His Val Phe Gln  Ala Leu Gln Tyr Leu  Arg Lys Leu 
    1565                 1570                 1575             


Cys Asn  His Pro Ala Leu Val  Leu Thr Pro Gln His  Pro Glu Phe 
    1580                 1585                 1590             


Lys Thr  Thr Ala Glu Lys Leu  Ala Val Gln Asn Ser  Ser Leu His 
    1595                 1600                 1605             


Asp Ile  Gln His Ala Pro Lys  Leu Ser Ala Leu Lys  Gln Leu Leu 
    1610                 1615                 1620             


Leu Asp  Cys Gly Leu Gly Asn  Gly Ser Thr Ser Glu  Ser Gly Thr 
    1625                 1630                 1635             


Glu Ser  Val Val Ala Gln His  Arg Ile Leu Ile Phe  Cys Gln Leu 
    1640                 1645                 1650             


Lys Ser  Met Leu Asp Ile Val  Glu His Asp Leu Leu  Lys Pro His 
    1655                 1660                 1665             


Leu Pro  Ser Val Thr Tyr Leu  Arg Leu Asp Gly Ser  Ile Pro Pro 
    1670                 1675                 1680             


Gly Gln  Arg His Ser Ile Val  Ser Arg Phe Asn Asn  Asp Pro Ser 
    1685                 1690                 1695             


Ile Asp  Val Leu Leu Leu Thr  Thr His Val Gly Gly  Leu Gly Leu 
    1700                 1705                 1710             


Asn Leu  Thr Gly Ala Asp Thr  Val Val Phe Val Glu  His Asp Trp 
    1715                 1720                 1725             


Asn Pro  Met Arg Asp Leu Gln  Ala Met Asp Arg Ala  His Arg Ile 
    1730                 1735                 1740             


Gly Gln  Lys Arg Val Val Asn  Val Tyr Arg Leu Ile  Thr Arg Gly 
    1745                 1750                 1755             


Thr Leu  Glu Glu Lys Ile Met  Gly Leu Gln Lys Phe  Lys Met Asn 
    1760                 1765                 1770             


Ile Ala  Asn Thr Val Ile Ser  Gln Glu Asn Ser Ser  Leu Gln Ser 
    1775                 1780                 1785             


Met Gly  Thr Asp Gln Leu Leu  Asp Leu Phe Thr Leu  Asp Lys Asp 
    1790                 1795                 1800             


Gly Lys  Ala Glu Lys Ala Asp  Thr Ser Thr Ser Gly  Lys Ala Ser 
    1805                 1810                 1815             


Met Lys  Ser Ile Leu Glu Asn  Leu Ser Asp Leu Trp  Asp Gln Glu 
    1820                 1825                 1830             


Gln Tyr  Asp Ser Glu Tyr Ser  Leu Glu Asn Phe Met  His Ser Leu 
    1835                 1840                 1845             


Lys 
    


<210>  3735
<211>  845
<212>  PRT
<213>  homo sapiens

<400>  3735

Met Leu Ser Gly Val Trp Phe Leu Ser Val Leu Thr Val Ala Gly Ile 
1               5                   10                  15      


Leu Gln Thr Glu Ser Arg Lys Thr Ala Lys Asp Ile Cys Lys Ile Arg 
            20                  25                  30          


Cys Leu Cys Glu Glu Lys Glu Asn Val Leu Asn Ile Asn Cys Glu Asn 
        35                  40                  45              


Lys Gly Phe Thr Thr Val Ser Leu Leu Gln Pro Pro Gln Tyr Arg Ile 
    50                  55                  60                  


Tyr Gln Leu Phe Leu Asn Gly Asn Leu Leu Thr Arg Leu Tyr Pro Asn 
65                  70                  75                  80  


Glu Phe Val Asn Tyr Ser Asn Ala Val Thr Leu His Leu Gly Asn Asn 
                85                  90                  95      


Gly Leu Gln Glu Ile Arg Thr Gly Ala Phe Ser Gly Leu Lys Thr Leu 
            100                 105                 110         


Lys Arg Leu His Leu Asn Asn Asn Lys Leu Glu Ile Leu Arg Glu Asp 
        115                 120                 125             


Thr Phe Leu Gly Leu Glu Ser Leu Glu Tyr Leu Gln Ala Asp Tyr Asn 
    130                 135                 140                 


Tyr Ile Ser Ala Ile Glu Ala Gly Ala Phe Ser Lys Leu Asn Lys Leu 
145                 150                 155                 160 


Lys Val Leu Ile Leu Asn Asp Asn Leu Leu Leu Ser Leu Pro Ser Asn 
                165                 170                 175     


Val Phe Arg Phe Val Leu Leu Thr His Leu Asp Leu Arg Gly Asn Arg 
            180                 185                 190         


Leu Lys Val Met Pro Phe Ala Gly Val Leu Glu His Ile Gly Gly Ile 
        195                 200                 205             


Met Glu Ile Gln Leu Glu Glu Asn Pro Trp Asn Cys Thr Cys Asp Leu 
    210                 215                 220                 


Leu Pro Leu Lys Ala Trp Leu Asp Thr Ile Thr Val Phe Val Gly Glu 
225                 230                 235                 240 


Ile Val Cys Glu Thr Pro Phe Arg Leu His Gly Lys Asp Val Thr Gln 
                245                 250                 255     


Leu Thr Arg Gln Asp Leu Cys Pro Arg Lys Ser Ala Ser Asp Ser Ser 
            260                 265                 270         


Gln Arg Gly Ser His Ala Asp Thr His Val Gln Arg Leu Ser Pro Thr 
        275                 280                 285             


Met Asn Pro Ala Leu Asn Pro Thr Arg Ala Pro Lys Ala Ser Arg Pro 
    290                 295                 300                 


Pro Lys Met Arg Asn Arg Pro Thr Pro Arg Val Thr Val Ser Lys Asp 
305                 310                 315                 320 


Arg Gln Ser Phe Gly Pro Ile Met Val Tyr Gln Thr Lys Ser Pro Val 
                325                 330                 335     


Pro Leu Thr Cys Pro Ser Ser Cys Val Cys Thr Ser Gln Ser Ser Asp 
            340                 345                 350         


Asn Gly Leu Asn Val Asn Cys Gln Glu Arg Lys Phe Thr Asn Ile Ser 
        355                 360                 365             


Asp Leu Gln Pro Lys Pro Thr Ser Pro Lys Lys Leu Tyr Leu Thr Gly 
    370                 375                 380                 


Asn Tyr Leu Gln Thr Val Tyr Lys Asn Asp Leu Leu Glu Tyr Ser Ser 
385                 390                 395                 400 


Leu Asp Leu Leu His Leu Gly Asn Asn Arg Ile Ala Val Ile Gln Glu 
                405                 410                 415     


Gly Ala Phe Thr Asn Leu Thr Ser Leu Arg Arg Leu Tyr Leu Asn Gly 
            420                 425                 430         


Asn Tyr Leu Glu Val Leu Tyr Pro Ser Met Phe Asp Gly Leu Gln Ser 
        435                 440                 445             


Leu Gln Tyr Leu Tyr Leu Glu Tyr Asn Val Ile Lys Glu Ile Lys Pro 
    450                 455                 460                 


Leu Thr Phe Asp Ala Leu Ile Asn Leu Gln Leu Leu Phe Leu Asn Asn 
465                 470                 475                 480 


Asn Leu Leu Arg Ser Leu Pro Asp Asn Ile Phe Gly Gly Thr Ala Leu 
                485                 490                 495     


Thr Arg Leu Asn Leu Arg Asn Asn His Phe Ser His Leu Pro Val Lys 
            500                 505                 510         


Gly Val Leu Asp Gln Leu Pro Ala Phe Ile Gln Ile Asp Leu Gln Glu 
        515                 520                 525             


Asn Pro Trp Asp Cys Thr Cys Asp Ile Met Gly Leu Lys Asp Trp Thr 
    530                 535                 540                 


Glu His Ala Asn Ser Pro Val Ile Ile Asn Glu Val Thr Cys Glu Ser 
545                 550                 555                 560 


Pro Ala Lys His Ala Gly Glu Ile Leu Lys Phe Leu Gly Arg Glu Ala 
                565                 570                 575     


Ile Cys Pro Asp Ser Pro Asn Leu Ser Asp Gly Thr Val Leu Ser Met 
            580                 585                 590         


Asn His Asn Thr Asp Thr Pro Arg Ser Leu Ser Val Ser Pro Ser Ser 
        595                 600                 605             


Tyr Pro Glu Leu His Thr Glu Val Pro Leu Ser Val Leu Ile Leu Gly 
    610                 615                 620                 


Leu Leu Val Val Phe Ile Leu Ser Val Cys Phe Gly Ala Gly Leu Phe 
625                 630                 635                 640 


Val Phe Val Leu Lys Arg Arg Lys Gly Val Pro Ser Val Pro Arg Asn 
                645                 650                 655     


Thr Asn Asn Leu Asp Val Ser Ser Phe Gln Leu Gln Tyr Gly Ser Tyr 
            660                 665                 670         


Asn Thr Glu Thr His Asp Lys Thr Asp Gly His Val Tyr Asn Tyr Ile 
        675                 680                 685             


Pro Pro Pro Val Gly Gln Met Cys Gln Asn Pro Ile Tyr Met Gln Lys 
    690                 695                 700                 


Glu Gly Asp Pro Val Ala Tyr Tyr Arg Asn Leu Gln Glu Phe Ser Tyr 
705                 710                 715                 720 


Ser Asn Leu Glu Glu Lys Lys Glu Glu Pro Ala Thr Pro Ala Tyr Thr 
                725                 730                 735     


Ile Ser Ala Thr Glu Leu Leu Glu Lys Gln Ala Thr Pro Arg Glu Pro 
            740                 745                 750         


Glu Leu Leu Tyr Gln Asn Ile Ala Glu Arg Val Lys Glu Leu Pro Ser 
        755                 760                 765             


Ala Gly Leu Val His Tyr Asn Phe Cys Thr Leu Pro Lys Arg Gln Phe 
    770                 775                 780                 


Ala Pro Ser Tyr Glu Ser Arg Arg Gln Asn Gln Asp Arg Ile Asn Lys 
785                 790                 795                 800 


Thr Val Leu Tyr Gly Thr Pro Arg Lys Cys Phe Val Gly Gln Ser Lys 
                805                 810                 815     


Pro Asn His Pro Leu Leu Gln Ala Lys Pro Gln Ser Glu Pro Asp Tyr 
            820                 825                 830         


Leu Glu Val Leu Glu Lys Gln Thr Ala Ile Ser Gln Leu 
        835                 840                 845 


<210>  3736
<211>  215
<212>  PRT
<213>  homo sapiens

<400>  3736

Met Thr Thr Leu Ala Gly Ala Val Pro Arg Met Met Arg Pro Gly Pro 
1               5                   10                  15      


Gly Gln Asn Tyr Pro Arg Ser Gly Phe Pro Leu Glu Val Ser Thr Pro 
            20                  25                  30          


Leu Gly Gln Gly Arg Val Asn Gln Leu Gly Gly Val Phe Ile Asn Gly 
        35                  40                  45              


Arg Pro Leu Pro Asn His Ile Arg His Lys Ile Val Glu Met Ala His 
    50                  55                  60                  


His Gly Ile Arg Pro Cys Val Ile Ser Arg Gln Leu Arg Val Ser His 
65                  70                  75                  80  


Gly Cys Val Ser Lys Ile Leu Cys Arg Tyr Gln Glu Thr Gly Ser Ile 
                85                  90                  95      


Arg Pro Gly Ala Ile Gly Gly Ser Lys Pro Lys Gln Val Thr Thr Pro 
            100                 105                 110         


Asp Val Glu Lys Lys Ile Glu Glu Tyr Lys Arg Glu Asn Pro Gly Met 
        115                 120                 125             


Phe Ser Trp Glu Ile Arg Asp Lys Leu Leu Lys Asp Ala Val Cys Asp 
    130                 135                 140                 


Arg Asn Thr Val Pro Ser Val Ser Ser Ile Ser Arg Ile Leu Arg Ser 
145                 150                 155                 160 


Lys Phe Gly Lys Gly Glu Glu Glu Glu Ala Asp Leu Glu Arg Lys Glu 
                165                 170                 175     


Ala Glu Glu Ser Glu Lys Lys Ala Lys His Ser Ile Asp Gly Ile Leu 
            180                 185                 190         


Ser Glu Arg Gly Lys Arg Trp Arg Leu Gly Arg Arg Thr Cys Trp Val 
        195                 200                 205             


Thr Trp Arg Ala Ser Ala Ser 
    210                 215 


<210>  3737
<211>  632
<212>  PRT
<213>  homo sapiens

<400>  3737

Met Ser Arg Val Arg Asp Ala Gly Cys Val Ala Ala Gly Ile Val Ile 
1               5                   10                  15      


Gly Ala Gly Ala Trp Tyr Cys Val Tyr Lys Tyr Thr Arg Gly Arg Asp 
            20                  25                  30          


Gln Thr Lys Lys Arg Met Ala Lys Pro Lys Asn Arg Ala Val Ala Gly 
        35                  40                  45              


Thr Gly Ala Arg Ala Arg Ala Gly Leu Arg Ala Gly Phe Thr Ile Asp 
    50                  55                  60                  


Leu Gly Ser Gly Phe Ser Pro Pro Thr Pro Val Arg Ala Glu Ala Glu 
65                  70                  75                  80  


Asp Arg Ala Gln Asp Glu Ala Ser Ala Leu Asp Thr Val Gly Ala Glu 
                85                  90                  95      


Ala Val Ala Pro Ala Ala Ser Ser Ala Glu Ala Gln Ser Gly Ala Gly 
            100                 105                 110         


Ser Gln Ala Gln Glu Ala Asp Gly Ala Gly Val Gly Pro Lys Ala Glu 
        115                 120                 125             


Ser Val Val Gly Ala Ala Met Ala Ser Ala Ile Ala Pro Pro Pro Gly 
    130                 135                 140                 


Val Thr Glu Ala Leu Gly Ala Ala Glu Ala Pro Ala Met Ala Gly Ala 
145                 150                 155                 160 


Pro Lys Val Ala Glu Ala Pro Arg Glu Ala Glu Thr Ser Arg Ala Ala 
                165                 170                 175     


Val Pro Pro Gly Thr Val Val Pro Thr Glu Ala Ala Ala Pro Thr Glu 
            180                 185                 190         


Val Thr Glu Gly Pro Gly Val Ala Ala Pro Thr Lys Val Ala Glu Ala 
        195                 200                 205             


Pro Gly Val Ala Ser Pro Thr Glu Ala Ala Glu Ala Pro Val Pro Ala 
    210                 215                 220                 


Thr Pro Thr Gly Ala Ala Ala Pro Thr Gly Ala Ala Glu Ser Pro Gly 
225                 230                 235                 240 


Thr Ser Gly Ser Pro Arg Thr Ala Val Val Pro Gly Thr Ser Ala Ala 
                245                 250                 255     


Lys Lys Ala Thr Pro Gly Ala His Thr Gly Ala Ile Pro Lys Ala Thr 
            260                 265                 270         


Ser Ala Thr Gly Ala Val Pro Lys Gly Gly Gly Lys Gly Val Thr Arg 
        275                 280                 285             


Ser Arg Asn Gly Gly Lys Gly Lys Gly Lys Lys Ser Lys Val Glu Val 
    290                 295                 300                 


Asp Glu Leu Gly Met Gly Phe Arg Pro Gly Asp Gly Ala Ala Ala Ala 
305                 310                 315                 320 


Ala Ala Ala Ser Ala Asn Gly Gly Gln Ala Phe Leu Ala Glu Val Pro 
                325                 330                 335     


Asp Ser Glu Glu Gly Glu Ser Gly Trp Thr Asp Thr Glu Ser Asp Ser 
            340                 345                 350         


Asp Ser Glu Pro Glu Thr Gln Arg Arg Gly Arg Gly Arg Arg Pro Val 
        355                 360                 365             


Ala Met Gln Lys Arg Pro Phe Pro Tyr Glu Ile Asp Glu Ile Leu Gly 
    370                 375                 380                 


Val Arg Asp Leu Arg Lys Val Leu Ala Leu Leu Gln Lys Ser Asp Asp 
385                 390                 395                 400 


Pro Phe Ile Gln Gln Val Ala Leu Leu Thr Leu Ser Asn Asn Ala Asn 
                405                 410                 415     


Tyr Ser Cys Asn Gln Glu Thr Ile Arg Lys Leu Gly Gly Leu Pro Ile 
            420                 425                 430         


Ile Ala Asn Met Ile Asn Lys Thr Asp Pro His Ile Lys Glu Lys Ala 
        435                 440                 445             


Leu Met Ala Met Asn Asn Leu Ser Glu Asn Tyr Glu Asn Gln Gly Arg 
    450                 455                 460                 


Leu Gln Val Tyr Met Asn Lys Val Met Asp Asp Ile Met Ala Ser Asn 
465                 470                 475                 480 


Leu Asn Ser Ala Val Gln Val Val Gly Leu Lys Phe Leu Thr Asn Met 
                485                 490                 495     


Thr Ile Thr Asn Asp Tyr Gln His Leu Leu Val Asn Ser Ile Ala Asn 
            500                 505                 510         


Phe Phe Arg Leu Leu Ser Gln Gly Gly Gly Lys Ile Lys Val Glu Ile 
        515                 520                 525             


Leu Lys Ile Leu Ser Asn Phe Ala Glu Asn Pro Asp Met Leu Lys Lys 
    530                 535                 540                 


Leu Leu Ser Thr Gln Val Pro Ala Ser Phe Ser Ser Leu Tyr Asn Ser 
545                 550                 555                 560 


Tyr Val Glu Ser Glu Ile Leu Ile Asn Ala Leu Thr Leu Phe Glu Ile 
                565                 570                 575     


Ile Tyr Asp Asn Leu Arg Ala Glu Val Phe Asn Tyr Arg Glu Phe Asn 
            580                 585                 590         


Lys Gly Ser Leu Phe Tyr Leu Cys Thr Thr Ser Gly Val Cys Val Lys 
        595                 600                 605             


Lys Ile Arg Ala Leu Ala Asn His His Asp Leu Leu Val Lys Val Lys 
    610                 615                 620                 


Val Ile Lys Leu Val Asn Lys Phe 
625                 630         


<210>  3738
<211>  242
<212>  PRT
<213>  homo sapiens

<400>  3738

Met Gly Ser Ala Cys Ile Lys Val Thr Lys Tyr Phe Leu Phe Leu Phe 
1               5                   10                  15      


Asn Leu Ile Phe Phe Ile Leu Gly Ala Val Ile Leu Gly Phe Gly Val 
            20                  25                  30          


Trp Ile Leu Ala Asp Lys Ser Ser Phe Ile Ser Val Leu Gln Thr Ser 
        35                  40                  45              


Ser Ser Ser Leu Arg Met Gly Ala Tyr Val Phe Ile Gly Val Gly Ala 
    50                  55                  60                  


Val Thr Met Leu Met Gly Phe Leu Gly Cys Ile Gly Ala Val Asn Glu 
65                  70                  75                  80  


Val Arg Cys Leu Leu Gly Leu Leu Lys Gln Glu Met Gly Gly Ile Val 
                85                  90                  95      


Thr Glu Leu Ile Arg Asp Tyr Asn Ser Ser Arg Glu Asp Ser Leu Gln 
            100                 105                 110         


Asp Ala Trp Asp Tyr Val Gln Ala Gln Val Lys Cys Cys Gly Trp Val 
        115                 120                 125             


Ser Phe Tyr Asn Trp Thr Asp Asn Ala Glu Leu Met Asn Arg Pro Glu 
    130                 135                 140                 


Val Thr Tyr Pro Cys Ser Cys Glu Val Lys Gly Glu Glu Asp Asn Ser 
145                 150                 155                 160 


Leu Ser Val Arg Lys Gly Phe Cys Glu Ala Pro Gly Asn Arg Thr Gln 
                165                 170                 175     


Ser Gly Asn His Pro Glu Asp Trp Pro Val Tyr Gln Glu Gly Cys Met 
            180                 185                 190         


Glu Lys Val Gln Ala Trp Leu Gln Glu Asn Leu Gly Ile Ile Leu Gly 
        195                 200                 205             


Val Gly Val Gly Val Ala Ile Ile Glu Leu Leu Gly Met Val Leu Ser 
    210                 215                 220                 


Ile Cys Leu Cys Arg His Val His Ser Glu Asp Tyr Ser Lys Val Pro 
225                 230                 235                 240 


Lys Tyr 
        


<210>  3739
<211>  1141
<212>  PRT
<213>  homo sapiens

<400>  3739

Met Asp Asp Ser Gly Glu Leu Gly Gly Leu Glu Thr Met Glu Thr Leu 
1               5                   10                  15      


Thr Glu Leu Gly Asp Glu Leu Thr Leu Gly Asp Ile Asp Glu Met Leu 
            20                  25                  30          


Gln Phe Val Ser Asn Gln Val Gly Glu Phe Pro Asp Leu Phe Ser Glu 
        35                  40                  45              


Gln Leu Cys Ser Ser Phe Pro Gly Ser Gly Gly Ser Gly Ser Ser Ser 
    50                  55                  60                  


Gly Ser Ser Gly Ser Ser Ser Ser Ser Ser Asn Gly Arg Gly Ser Ser 
65                  70                  75                  80  


Ser Gly Ala Val Asp Pro Ser Val Gln Arg Ser Phe Thr Gln Val Thr 
                85                  90                  95      


Leu Pro Ser Phe Ser Pro Ser Ala Ala Ser Pro Gln Ala Pro Thr Leu 
            100                 105                 110         


Gln Val Lys Val Ser Pro Thr Ser Val Pro Thr Thr Pro Arg Ala Thr 
        115                 120                 125             


Pro Ile Leu Gln Pro Arg Pro Gln Pro Gln Pro Gln Pro Gln Thr Gln 
    130                 135                 140                 


Leu Gln Gln Gln Thr Val Met Ile Thr Pro Thr Phe Ser Thr Thr Pro 
145                 150                 155                 160 


Gln Thr Arg Ile Ile Gln Gln Pro Leu Ile Tyr Gln Asn Ala Ala Thr 
                165                 170                 175     


Ser Phe Gln Val Leu Gln Pro Gln Val Gln Ser Leu Val Thr Ser Ser 
            180                 185                 190         


Gln Val Gln Pro Val Thr Ile Gln Gln Gln Val Gln Thr Val Gln Ala 
        195                 200                 205             


Gln Arg Val Leu Thr Gln Thr Ala Asn Gly Thr Leu Gln Thr Leu Ala 
    210                 215                 220                 


Pro Ala Thr Val Gln Thr Val Ala Ala Pro Gln Val Gln Gln Val Pro 
225                 230                 235                 240 


Val Leu Val Gln Pro Gln Ile Ile Lys Thr Asp Ser Leu Val Leu Thr 
                245                 250                 255     


Thr Leu Lys Thr Asp Gly Ser Pro Val Met Ala Ala Val Gln Asn Pro 
            260                 265                 270         


Ala Leu Thr Ala Leu Thr Thr Pro Ile Gln Thr Ala Ala Leu Gln Val 
        275                 280                 285             


Pro Thr Leu Val Gly Ser Ser Gly Thr Ile Leu Thr Thr Met Pro Val 
    290                 295                 300                 


Met Met Gly Gln Glu Lys Val Pro Ile Lys Gln Val Pro Gly Gly Val 
305                 310                 315                 320 


Lys Gln Leu Glu Pro Pro Lys Glu Gly Glu Arg Arg Thr Thr His Asn 
                325                 330                 335     


Ile Ile Glu Lys Arg Tyr Arg Ser Ser Ile Asn Asp Lys Ile Ile Glu 
            340                 345                 350         


Leu Lys Asp Leu Val Met Gly Thr Asp Ala Lys Met His Lys Ser Gly 
        355                 360                 365             


Val Leu Arg Lys Ala Ile Asp Tyr Ile Lys Tyr Leu Gln Gln Val Asn 
    370                 375                 380                 


His Lys Leu Arg Gln Glu Asn Met Val Leu Lys Leu Ala Asn Gln Lys 
385                 390                 395                 400 


Asn Lys Leu Leu Lys Gly Ile Asp Leu Gly Ser Leu Val Asp Asn Glu 
                405                 410                 415     


Val Asp Leu Lys Ile Glu Asp Phe Asn Gln Asn Val Leu Leu Met Ser 
            420                 425                 430         


Pro Pro Ala Ser Asp Ser Gly Ser Gln Ala Gly Phe Ser Pro Tyr Ser 
        435                 440                 445             


Ile Asp Ser Glu Pro Gly Ser Pro Leu Leu Asp Asp Ala Lys Val Lys 
    450                 455                 460                 


Asp Glu Pro Asp Ser Pro Pro Val Ala Leu Gly Met Val Asp Arg Ser 
465                 470                 475                 480 


Arg Ile Leu Leu Cys Val Leu Thr Phe Leu Cys Leu Ser Phe Asn Pro 
                485                 490                 495     


Leu Thr Ser Leu Leu Gln Trp Gly Gly Ala His Asp Ser Asp Gln His 
            500                 505                 510         


Pro His Ser Gly Ser Gly Arg Ser Val Leu Ser Phe Glu Ser Gly Ser 
        515                 520                 525             


Gly Gly Trp Phe Asp Trp Met Met Pro Thr Leu Leu Leu Trp Leu Val 
    530                 535                 540                 


Asn Gly Val Ile Val Leu Ser Val Phe Val Lys Leu Leu Val His Gly 
545                 550                 555                 560 


Glu Pro Val Ile Arg Pro His Ser Arg Ser Ser Val Thr Phe Trp Arg 
                565                 570                 575     


His Arg Lys Gln Ala Asp Leu Asp Leu Ala Arg Gly Asp Phe Ala Ala 
            580                 585                 590         


Ala Ala Gly Asn Leu Gln Thr Cys Leu Ala Val Leu Gly Arg Ala Leu 
        595                 600                 605             


Pro Thr Ser Arg Leu Asp Leu Ala Cys Ser Leu Ser Trp Asn Val Ile 
    610                 615                 620                 


Arg Tyr Ser Leu Gln Lys Leu Arg Leu Val Arg Trp Leu Leu Lys Lys 
625                 630                 635                 640 


Val Phe Gln Cys Arg Arg Ala Thr Pro Ala Thr Glu Ala Gly Phe Glu 
                645                 650                 655     


Asp Glu Ala Lys Thr Ser Ala Arg Asp Ala Ala Leu Ala Tyr His Arg 
            660                 665                 670         


Leu His Gln Leu His Ile Thr Gly Lys Leu Pro Ala Gly Ser Ala Cys 
        675                 680                 685             


Ser Asp Val His Met Ala Leu Cys Ala Val Asn Leu Ala Glu Cys Ala 
    690                 695                 700                 


Glu Glu Lys Ile Pro Pro Ser Thr Leu Val Glu Ile His Leu Thr Ala 
705                 710                 715                 720 


Ala Met Gly Leu Lys Thr Arg Cys Gly Gly Lys Leu Gly Phe Leu Ala 
                725                 730                 735     


Ser Tyr Phe Leu Ser Arg Ala Gln Ser Leu Cys Gly Pro Glu His Ser 
            740                 745                 750         


Ala Val Pro Asp Ser Leu Arg Trp Leu Cys His Pro Leu Gly Gln Lys 
        755                 760                 765             


Phe Phe Met Glu Arg Ser Trp Ser Val Lys Ser Ala Ala Lys Glu Ser 
    770                 775                 780                 


Leu Tyr Cys Ala Gln Arg Asn Pro Ala Asp Pro Ile Ala Gln Val His 
785                 790                 795                 800 


Gln Ala Phe Cys Lys Asn Leu Leu Glu Arg Ala Ile Glu Ser Leu Val 
                805                 810                 815     


Lys Pro Gln Ala Lys Lys Lys Ala Gly Asp Gln Glu Glu Glu Ser Cys 
            820                 825                 830         


Glu Phe Ser Ser Ala Leu Glu Tyr Leu Lys Leu Leu His Ser Phe Val 
        835                 840                 845             


Asp Ser Val Gly Val Met Ser Pro Pro Leu Ser Arg Ser Ser Val Leu 
    850                 855                 860                 


Lys Ser Ala Leu Gly Pro Asp Ile Ile Cys Arg Trp Trp Thr Ser Ala 
865                 870                 875                 880 


Ile Thr Val Ala Ile Ser Trp Leu Gln Gly Asp Asp Ala Ala Val Arg 
                885                 890                 895     


Ser His Phe Thr Lys Val Glu Arg Ile Pro Lys Ala Leu Glu Val Thr 
            900                 905                 910         


Glu Ser Pro Leu Val Lys Ala Ile Phe His Ala Cys Arg Ala Met His 
        915                 920                 925             


Ala Ser Leu Pro Gly Lys Ala Asp Gly Gln Gln Ser Ser Phe Cys His 
    930                 935                 940                 


Cys Glu Arg Ala Ser Gly His Leu Trp Ser Ser Leu Asn Val Ser Gly 
945                 950                 955                 960 


Ala Thr Ser Asp Pro Ala Leu Asn His Val Val Gln Leu Leu Thr Cys 
                965                 970                 975     


Asp Leu Leu Leu Ser Leu Arg Thr Ala Leu Trp Gln Lys Gln Ala Ser 
            980                 985                 990         


Ala Ser Gln Ala Val Gly Glu Thr  Tyr His Ala Ser Gly  Ala Glu Leu 
        995                 1000                 1005             


Ala Gly  Phe Gln Arg Asp Leu  Gly Ser Leu Arg Arg  Leu Ala His 
    1010                 1015                 1020             


Ser Phe  Arg Pro Ala Tyr Arg  Lys Val Phe Leu His  Glu Ala Thr 
    1025                 1030                 1035             


Val Arg  Leu Met Ala Gly Ala  Ser Pro Thr Arg Thr  His Gln Leu 
    1040                 1045                 1050             


Leu Glu  His Ser Leu Arg Arg  Arg Thr Thr Gln Ser  Thr Lys His 
    1055                 1060                 1065             


Gly Glu  Val Asp Ala Trp Pro  Gly Gln Arg Glu Arg  Ala Thr Ala 
    1070                 1075                 1080             


Ile Leu  Leu Ala Cys Arg His  Leu Pro Leu Ser Phe  Leu Ser Ser 
    1085                 1090                 1095             


Pro Gly  Gln Arg Ala Val Leu  Leu Ala Glu Ala Ala  Arg Thr Leu 
    1100                 1105                 1110             


Glu Lys  Val Gly Asp Arg Arg  Ser Cys Asn Asp Cys  Gln Gln Met 
    1115                 1120                 1125             


Ile Val  Lys Leu Gly Gly Gly  Thr Ala Ile Ala Ala  Ser 
    1130                 1135                 1140     


<210>  3740
<211>  169
<212>  PRT
<213>  homo sapiens

<400>  3740

Met Phe Gln Pro Ala Pro Lys Arg Cys Phe Thr Ile Glu Ser Leu Val 
1               5                   10                  15      


Ala Lys Asp Ser Pro Leu Pro Ala Ser Arg Ser Glu Asp Pro Ile Arg 
            20                  25                  30          


Pro Ala Ala Leu Ser Tyr Ala Asn Ser Ser Pro Ile Asn Pro Phe Leu 
        35                  40                  45              


Asn Gly Phe His Ser Ala Ala Ala Ala Ala Ala Gly Arg Gly Val Tyr 
    50                  55                  60                  


Ser Asn Pro Asp Leu Val Phe Ala Glu Ala Val Ser His Pro Pro Asn 
65                  70                  75                  80  


Pro Ala Val Pro Val His Pro Val Pro Pro Pro His Ala Leu Ala Ala 
                85                  90                  95      


His Pro Leu Pro Ser Ser His Ser Pro His Pro Leu Phe Ala Ser Gln 
            100                 105                 110         


Gln Arg Asp Pro Ser Thr Phe Tyr Pro Trp Leu Ile His Arg Tyr Arg 
        115                 120                 125             


Tyr Leu Gly His Arg Phe Gln Gly Lys Ser Met Val Ser Glu Pro Lys 
    130                 135                 140                 


Asn Lys Val Gln Lys Ala Glu Ala Gly Gly Arg Arg Leu Arg Phe Ala 
145                 150                 155                 160 


Thr Lys Glu Lys Arg Asp Ala Pro Tyr 
                165                 


<210>  3741
<211>  333
<212>  PRT
<213>  homo sapiens

<400>  3741

Met Glu Glu Asn Asp Pro Lys Pro Gly Glu Ala Ala Ala Ala Val Glu 
1               5                   10                  15      


Gly Gln Arg Gln Pro Glu Ser Ser Pro Gly Gly Gly Ser Gly Gly Gly 
            20                  25                  30          


Gly Gly Ser Ser Pro Gly Glu Ala Asp Thr Gly Arg Arg Arg Ala Leu 
        35                  40                  45              


Met Leu Pro Ala Val Leu Gln Ala Pro Gly Asn His Gln His Pro His 
    50                  55                  60                  


Arg Ile Thr Asn Phe Phe Ile Asp Asn Ile Leu Arg Pro Glu Phe Gly 
65                  70                  75                  80  


Arg Arg Lys Asp Ala Gly Thr Cys Cys Ala Gly Ala Gly Gly Gly Arg 
                85                  90                  95      


Gly Gly Gly Ala Gly Gly Glu Gly Gly Ala Ser Gly Ala Glu Gly Gly 
            100                 105                 110         


Gly Gly Ala Gly Gly Ser Glu Gln Leu Leu Gly Ser Gly Ser Arg Glu 
        115                 120                 125             


Pro Arg Gln Asn Pro Pro Cys Ala Pro Gly Ala Gly Gly Pro Leu Pro 
    130                 135                 140                 


Ala Ala Gly Ser Asp Ser Pro Gly Asp Gly Glu Gly Gly Ser Lys Thr 
145                 150                 155                 160 


Leu Ser Leu His Gly Gly Ala Lys Lys Gly Gly Asp Pro Gly Gly Pro 
                165                 170                 175     


Leu Asp Gly Ser Leu Lys Ala Arg Gly Leu Gly Gly Gly Asp Leu Ser 
            180                 185                 190         


Val Ser Ser Asp Ser Asp Ser Ser Gln Ala Gly Ala Asn Leu Gly Ala 
        195                 200                 205             


Gln Pro Met Leu Trp Pro Ala Trp Val Tyr Cys Thr Arg Tyr Ser Asp 
    210                 215                 220                 


Arg Pro Ser Ser Gly Pro Arg Ser Arg Lys Pro Lys Lys Lys Asn Pro 
225                 230                 235                 240 


Asn Lys Glu Asp Lys Arg Pro Arg Thr Ala Phe Thr Ala Glu Gln Leu 
                245                 250                 255     


Gln Arg Leu Lys Ala Glu Phe Gln Thr Asn Arg Tyr Leu Thr Glu Gln 
            260                 265                 270         


Arg Arg Gln Ser Leu Ala Gln Glu Leu Ser Leu Asn Glu Ser Gln Ile 
        275                 280                 285             


Lys Ile Trp Phe Gln Asn Lys Arg Ala Lys Ile Lys Lys Ala Thr Gly 
    290                 295                 300                 


Asn Lys Asn Thr Leu Ala Val His Leu Met Ala Gln Gly Leu Tyr Asn 
305                 310                 315                 320 


His Ser Thr Thr Ala Lys Glu Gly Lys Ser Asp Ser Glu 
                325                 330             


<210>  3742
<211>  1224
<212>  PRT
<213>  homo sapiens

<400>  3742

Met Glu Pro Leu Leu Leu Gly Arg Gly Leu Ile Val Tyr Leu Met Phe 
1               5                   10                  15      


Leu Leu Leu Lys Phe Ser Lys Ala Ile Glu Ile Pro Ser Ser Val Gln 
            20                  25                  30          


Gln Val Pro Thr Ile Ile Lys Gln Ser Lys Val Gln Val Ala Phe Pro 
        35                  40                  45              


Phe Asp Glu Tyr Phe Gln Ile Glu Cys Glu Ala Lys Gly Asn Pro Glu 
    50                  55                  60                  


Pro Thr Phe Ser Trp Thr Lys Asp Gly Asn Pro Phe Tyr Phe Thr Asp 
65                  70                  75                  80  


His Arg Ile Ile Pro Ser Asn Asn Ser Gly Thr Phe Arg Ile Pro Asn 
                85                  90                  95      


Glu Gly His Ile Ser His Phe Gln Gly Lys Tyr Arg Cys Phe Ala Ser 
            100                 105                 110         


Asn Lys Leu Gly Ile Ala Met Ser Glu Glu Ile Glu Phe Ile Val Pro 
        115                 120                 125             


Ser Val Pro Lys Phe Pro Lys Glu Lys Ile Asp Pro Leu Glu Val Glu 
    130                 135                 140                 


Glu Gly Asp Pro Ile Val Leu Pro Cys Asn Pro Pro Lys Gly Leu Pro 
145                 150                 155                 160 


Pro Leu His Ile Tyr Trp Met Asn Ile Glu Leu Glu His Ile Glu Gln 
                165                 170                 175     


Asp Glu Arg Val Tyr Met Ser Gln Lys Gly Asp Leu Tyr Phe Ala Asn 
            180                 185                 190         


Val Glu Glu Lys Asp Ser Arg Asn Asp Tyr Cys Cys Phe Ala Ala Phe 
        195                 200                 205             


Pro Arg Leu Arg Thr Ile Val Gln Lys Met Pro Met Lys Leu Thr Val 
    210                 215                 220                 


Asn Ser Leu Lys His Ala Asn Asp Ser Ser Ser Ser Thr Glu Ile Gly 
225                 230                 235                 240 


Ser Lys Ala Asn Ser Ile Lys Gln Arg Lys Pro Lys Leu Leu Leu Pro 
                245                 250                 255     


Pro Thr Glu Ser Gly Ser Glu Ser Ser Ile Thr Ile Leu Lys Gly Glu 
            260                 265                 270         


Ile Leu Leu Leu Glu Cys Phe Ala Glu Gly Leu Pro Thr Pro Gln Val 
        275                 280                 285             


Asp Trp Asn Lys Ile Gly Gly Asp Leu Pro Lys Gly Arg Glu Thr Lys 
    290                 295                 300                 


Glu Asn Tyr Gly Lys Thr Leu Lys Ile Glu Asn Val Ser Tyr Gln Asp 
305                 310                 315                 320 


Lys Gly Asn Tyr Arg Cys Thr Ala Ser Asn Phe Leu Gly Thr Ala Thr 
                325                 330                 335     


His Asp Phe His Val Ile Val Glu Glu Pro Pro Arg Trp Thr Lys Lys 
            340                 345                 350         


Pro Gln Ser Ala Val Tyr Ser Thr Gly Ser Asn Gly Ile Leu Leu Cys 
        355                 360                 365             


Glu Ala Glu Gly Glu Pro Gln Pro Thr Ile Lys Trp Arg Val Asn Gly 
    370                 375                 380                 


Ser Pro Val Asp Asn His Pro Phe Ala Gly Asp Val Val Phe Pro Arg 
385                 390                 395                 400 


Glu Ile Ser Phe Thr Asn Leu Gln Pro Asn His Thr Ala Val Tyr Gln 
                405                 410                 415     


Cys Glu Ala Ser Asn Val His Gly Thr Ile Leu Ala Asn Ala Asn Ile 
            420                 425                 430         


Asp Val Val Asp Val Arg Pro Leu Ile Gln Thr Lys Asp Gly Glu Asn 
        435                 440                 445             


Tyr Ala Thr Val Val Gly Tyr Ser Ala Phe Leu His Cys Glu Phe Phe 
    450                 455                 460                 


Ala Ser Pro Glu Ala Val Val Ser Trp Gln Lys Val Glu Glu Val Lys 
465                 470                 475                 480 


Pro Leu Glu Gly Arg Arg Tyr His Ile Tyr Glu Asn Gly Thr Leu Gln 
                485                 490                 495     


Ile Asn Arg Thr Thr Glu Glu Asp Ala Gly Ser Tyr Ser Cys Trp Val 
            500                 505                 510         


Glu Asn Ala Ile Gly Lys Thr Ala Val Thr Ala Asn Leu Asp Ile Arg 
        515                 520                 525             


Asn Ala Thr Lys Leu Arg Val Ser Pro Lys Asn Pro Arg Ile Pro Lys 
    530                 535                 540                 


Leu His Met Leu Glu Leu His Cys Glu Ser Lys Cys Asp Ser His Leu 
545                 550                 555                 560 


Lys His Ser Leu Lys Leu Ser Trp Ser Lys Asp Gly Glu Ala Phe Glu 
                565                 570                 575     


Ile Asn Gly Thr Glu Asp Gly Arg Ile Ile Ile Asp Gly Ala Asn Leu 
            580                 585                 590         


Thr Ile Ser Asn Val Thr Leu Glu Asp Gln Gly Ile Tyr Cys Cys Ser 
        595                 600                 605             


Ala His Thr Ala Leu Asp Ser Ala Ala Asp Ile Thr Gln Val Thr Val 
    610                 615                 620                 


Leu Asp Val Pro Asp Pro Pro Glu Asn Leu His Leu Ser Glu Arg Gln 
625                 630                 635                 640 


Asn Arg Ser Val Arg Leu Thr Trp Glu Ala Gly Ala Asp His Asn Ser 
                645                 650                 655     


Asn Ile Ser Glu Tyr Ile Val Glu Phe Glu Gly Asn Lys Glu Glu Pro 
            660                 665                 670         


Gly Arg Trp Glu Glu Leu Thr Arg Val Gln Gly Lys Lys Thr Thr Val 
        675                 680                 685             


Ile Leu Pro Leu Ala Pro Phe Val Arg Tyr Gln Phe Arg Val Ile Ala 
    690                 695                 700                 


Val Asn Glu Val Gly Arg Ser Gln Pro Ser Gln Pro Ser Asp His His 
705                 710                 715                 720 


Glu Thr Pro Pro Ala Ala Pro Asp Arg Asn Pro Gln Asn Ile Arg Val 
                725                 730                 735     


Gln Ala Ser Gln Pro Lys Glu Met Ile Ile Lys Trp Glu Pro Leu Lys 
            740                 745                 750         


Ser Met Glu Gln Asn Gly Pro Gly Leu Glu Tyr Arg Val Thr Trp Lys 
        755                 760                 765             


Pro Gln Gly Ala Pro Val Glu Trp Glu Glu Glu Thr Val Thr Asn His 
    770                 775                 780                 


Thr Leu Arg Val Met Thr Pro Ala Val Tyr Ala Pro Tyr Asp Val Lys 
785                 790                 795                 800 


Val Gln Ala Ile Asn Gln Leu Gly Ser Gly Pro Asp Pro Gln Ser Val 
                805                 810                 815     


Thr Leu Tyr Ser Gly Glu Asp Tyr Pro Asp Thr Ala Pro Val Ile His 
            820                 825                 830         


Gly Val Asp Val Ile Asn Ser Thr Leu Val Lys Val Thr Trp Ser Thr 
        835                 840                 845             


Val Pro Lys Asp Arg Val His Gly Arg Leu Lys Gly Tyr Gln Ile Asn 
    850                 855                 860                 


Trp Trp Lys Thr Lys Ser Leu Leu Asp Gly Arg Thr His Pro Lys Glu 
865                 870                 875                 880 


Val Asn Ile Leu Arg Phe Ser Gly Gln Arg Asn Ser Gly Met Val Pro 
                885                 890                 895     


Ser Leu Asp Ala Phe Ser Glu Phe His Leu Thr Val Leu Ala Tyr Asn 
            900                 905                 910         


Ser Lys Gly Ala Gly Pro Glu Ser Glu Pro Tyr Ile Phe Gln Thr Pro 
        915                 920                 925             


Glu Gly Val Pro Glu Gln Pro Thr Phe Leu Lys Val Ile Lys Val Asp 
    930                 935                 940                 


Lys Asp Thr Ala Thr Leu Ser Trp Gly Leu Pro Lys Lys Leu Asn Gly 
945                 950                 955                 960 


Asn Leu Thr Gly Tyr Leu Leu Gln Tyr Gln Ile Ile Asn Asp Thr Tyr 
                965                 970                 975     


Glu Ile Gly Glu Leu Asn Asp Ile Asn Ile Thr Thr Pro Ser Lys Pro 
            980                 985                 990         


Ser Trp His Leu Ser Asn Leu Asn  Ala Thr Thr Lys Tyr  Lys Phe Tyr 
        995                 1000                 1005             


Leu Arg  Ala Cys Thr Ser Gln  Gly Cys Gly Lys Pro  Ile Thr Glu 
    1010                 1015                 1020             


Glu Ser  Ser Thr Leu Gly Glu  Gly Ser Lys Gly Ile  Gly Lys Ile 
    1025                 1030                 1035             


Ser Gly  Val Asn Leu Thr Gln  Lys Thr His Pro Ile  Glu Val Phe 
    1040                 1045                 1050             


Glu Pro  Gly Ala Glu His Ile  Val Arg Leu Met Thr  Lys Asn Trp 
    1055                 1060                 1065             


Gly Asp  Asn Asp Ser Ile Phe  Gln Asp Val Ile Glu  Thr Arg Gly 
    1070                 1075                 1080             


Arg Glu  Tyr Ala Gly Leu Tyr  Asp Asp Ile Ser Thr  Gln Gly Trp 
    1085                 1090                 1095             


Phe Ile  Gly Leu Met Cys Ala  Ile Ala Leu Leu Thr  Leu Leu Leu 
    1100                 1105                 1110             


Leu Thr  Val Cys Phe Val Lys  Arg Asn Arg Gly Gly  Lys Tyr Ser 
    1115                 1120                 1125             


Val Lys  Glu Lys Glu Asp Leu  His Pro Asp Pro Glu  Ile Gln Ser 
    1130                 1135                 1140             


Val Lys  Asp Glu Thr Phe Gly  Glu Tyr Ser Asp Ser  Asp Glu Lys 
    1145                 1150                 1155             


Pro Leu  Lys Gly Ser Leu Arg  Ser Leu Asn Arg Asp  Met Gln Pro 
    1160                 1165                 1170             


Thr Glu  Ser Ala Asp Ser Leu  Val Glu Tyr Gly Glu  Gly Asp His 
    1175                 1180                 1185             


Gly Leu  Phe Ser Glu Asp Gly  Ser Phe Ile Gly Ala  Tyr Ala Gly 
    1190                 1195                 1200             


Ser Lys  Glu Lys Gly Ser Val  Glu Ser Asn Gly Ser  Ser Thr Ala 
    1205                 1210                 1215             


Thr Phe  Pro Leu Arg Ala 
    1220                 


<210>  3743
<211>  915
<212>  PRT
<213>  homo sapiens

<400>  3743

Met Ala Arg Arg Ser Ser Phe Gln Ser Cys Gln Ile Ile Ser Leu Phe 
1               5                   10                  15      


Thr Phe Ala Val Gly Val Asn Ile Cys Leu Gly Phe Thr Ala His Arg 
            20                  25                  30          


Ile Lys Arg Ala Glu Gly Trp Glu Glu Gly Pro Pro Thr Val Leu Ser 
        35                  40                  45              


Asp Ser Pro Trp Thr Asn Ile Ser Gly Ser Cys Lys Gly Arg Cys Phe 
    50                  55                  60                  


Glu Leu Gln Glu Ala Gly Pro Pro Asp Cys Arg Cys Asp Asn Leu Cys 
65                  70                  75                  80  


Lys Ser Tyr Thr Ser Cys Cys His Asp Phe Asp Glu Leu Cys Leu Lys 
                85                  90                  95      


Thr Ala Arg Gly Trp Glu Cys Thr Lys Asp Arg Cys Gly Glu Val Arg 
            100                 105                 110         


Asn Glu Glu Asn Ala Cys His Cys Ser Glu Asp Cys Leu Ala Arg Gly 
        115                 120                 125             


Asp Cys Cys Thr Asn Tyr Gln Val Val Cys Lys Gly Glu Ser His Trp 
    130                 135                 140                 


Val Asp Asp Asp Cys Glu Glu Ile Lys Ala Ala Glu Cys Pro Ala Gly 
145                 150                 155                 160 


Phe Val Arg Pro Pro Leu Ile Ile Phe Ser Val Asp Gly Phe Arg Ala 
                165                 170                 175     


Ser Tyr Met Lys Lys Gly Ser Lys Val Met Pro Asn Ile Glu Lys Leu 
            180                 185                 190         


Arg Ser Cys Gly Thr His Ser Pro Tyr Met Arg Pro Val Tyr Pro Thr 
        195                 200                 205             


Lys Thr Phe Pro Asn Leu Tyr Thr Leu Ala Thr Gly Leu Tyr Pro Glu 
    210                 215                 220                 


Ser His Gly Ile Val Gly Asn Ser Met Tyr Asp Pro Val Phe Asp Ala 
225                 230                 235                 240 


Thr Phe His Leu Arg Gly Arg Glu Lys Phe Asn His Arg Trp Trp Gly 
                245                 250                 255     


Gly Gln Pro Leu Trp Ile Thr Ala Thr Lys Gln Gly Val Lys Ala Gly 
            260                 265                 270         


Thr Phe Phe Trp Ser Val Val Ile Pro His Glu Arg Arg Ile Leu Thr 
        275                 280                 285             


Ile Leu Gln Trp Leu Thr Leu Pro Asp His Glu Arg Pro Ser Val Tyr 
    290                 295                 300                 


Ala Phe Tyr Ser Glu Gln Pro Asp Phe Ser Gly His Lys Tyr Gly Pro 
305                 310                 315                 320 


Phe Gly Pro Glu Glu Ser Ser Tyr Gly Ser Pro Phe Thr Pro Ala Lys 
                325                 330                 335     


Arg Pro Lys Arg Lys Val Ala Pro Lys Arg Arg Gln Glu Arg Pro Val 
            340                 345                 350         


Ala Pro Pro Lys Lys Arg Arg Arg Lys Ile His Arg Met Asp His Tyr 
        355                 360                 365             


Ala Ala Glu Thr Arg Gln Asp Lys Met Thr Asn Pro Leu Arg Glu Ile 
    370                 375                 380                 


Asp Lys Ile Val Gly Gln Leu Met Asp Gly Leu Lys Gln Leu Lys Leu 
385                 390                 395                 400 


His Arg Cys Val Asn Val Ile Phe Val Gly Asp His Gly Met Glu Asp 
                405                 410                 415     


Val Thr Cys Asp Arg Thr Glu Phe Leu Ser Asn Tyr Leu Thr Asn Val 
            420                 425                 430         


Asp Asp Ile Thr Leu Val Pro Gly Thr Leu Gly Arg Ile Arg Ser Lys 
        435                 440                 445             


Phe Ser Asn Asn Ala Lys Tyr Asp Pro Lys Ala Ile Ile Ala Asn Leu 
    450                 455                 460                 


Thr Cys Lys Lys Pro Asp Gln His Phe Lys Pro Tyr Leu Lys Gln His 
465                 470                 475                 480 


Leu Pro Lys Arg Leu His Tyr Ala Asn Asn Arg Arg Ile Glu Asp Ile 
                485                 490                 495     


His Leu Leu Val Glu Arg Arg Trp His Val Ala Arg Lys Pro Leu Asp 
            500                 505                 510         


Val Tyr Lys Lys Pro Ser Gly Lys Cys Phe Phe Gln Gly Asp His Gly 
        515                 520                 525             


Phe Asp Asn Lys Val Asn Ser Met Gln Thr Val Phe Val Gly Tyr Gly 
    530                 535                 540                 


Ser Thr Phe Lys Tyr Lys Thr Lys Val Pro Pro Phe Glu Asn Ile Glu 
545                 550                 555                 560 


Leu Tyr Asn Val Met Cys Asp Leu Leu Gly Leu Lys Pro Ala Pro Asn 
                565                 570                 575     


Asn Gly Thr His Gly Ser Leu Asn His Leu Leu Arg Thr Asn Thr Phe 
            580                 585                 590         


Arg Pro Thr Met Pro Glu Glu Val Thr Arg Pro Asn Tyr Pro Gly Ile 
        595                 600                 605             


Met Tyr Leu Gln Ser Asp Phe Asp Leu Gly Cys Thr Cys Asp Asp Lys 
    610                 615                 620                 


Val Glu Pro Lys Asn Lys Leu Asp Glu Leu Asn Lys Arg Leu His Thr 
625                 630                 635                 640 


Lys Gly Ser Thr Glu Glu Arg His Leu Leu Tyr Gly Arg Pro Ala Val 
                645                 650                 655     


Leu Tyr Arg Thr Arg Tyr Asp Ile Leu Tyr His Thr Asp Phe Glu Ser 
            660                 665                 670         


Gly Tyr Ser Glu Ile Phe Leu Met Pro Leu Trp Thr Ser Tyr Thr Val 
        675                 680                 685             


Ser Lys Gln Ala Glu Val Ser Ser Val Pro Asp His Leu Thr Ser Cys 
    690                 695                 700                 


Val Arg Pro Asp Val Arg Val Ser Pro Ser Phe Ser Gln Asn Cys Leu 
705                 710                 715                 720 


Ala Tyr Lys Asn Asp Lys Gln Met Ser Tyr Gly Phe Leu Phe Pro Pro 
                725                 730                 735     


Tyr Leu Ser Ser Ser Pro Glu Ala Lys Tyr Asp Ala Phe Leu Val Thr 
            740                 745                 750         


Asn Met Val Pro Met Tyr Pro Ala Phe Lys Arg Val Trp Asn Tyr Phe 
        755                 760                 765             


Gln Arg Val Leu Val Lys Lys Tyr Ala Ser Glu Arg Asn Gly Val Asn 
    770                 775                 780                 


Val Ile Ser Gly Pro Ile Phe Asp Tyr Asp Tyr Asp Gly Leu His Asp 
785                 790                 795                 800 


Thr Glu Asp Lys Ile Lys Gln Tyr Val Glu Gly Ser Ser Ile Pro Val 
                805                 810                 815     


Pro Thr His Tyr Tyr Ser Ile Ile Thr Ser Cys Leu Asp Phe Thr Gln 
            820                 825                 830         


Pro Ala Asp Lys Cys Asp Gly Pro Leu Ser Val Ser Ser Phe Ile Leu 
        835                 840                 845             


Pro His Arg Pro Asp Asn Glu Glu Ser Cys Asn Ser Ser Glu Asp Glu 
    850                 855                 860                 


Ser Lys Trp Val Glu Glu Leu Met Lys Met His Thr Ala Arg Val Arg 
865                 870                 875                 880 


Asp Ile Glu His Leu Thr Ser Leu Asp Phe Phe Arg Lys Thr Ser Arg 
                885                 890                 895     


Ser Tyr Pro Glu Ile Leu Thr Leu Lys Thr Tyr Leu His Thr Tyr Glu 
            900                 905                 910         


Ser Glu Ile 
        915 


<210>  3744
<211>  86
<212>  PRT
<213>  homo sapiens

<400>  3744

Met Asn Ser Lys Gly Gln Tyr Pro Thr Gln Pro Thr Tyr Pro Val Gln 
1               5                   10                  15      


Pro Pro Gly Asn Pro Val Tyr Pro Gln Thr Leu His Leu Pro Gln Ala 
            20                  25                  30          


Pro Pro Tyr Thr Asp Ala Pro Pro Ala Tyr Ser Glu Pro Pro Pro Pro 
        35                  40                  45              


Gly Cys Pro Pro Asn Ala Ala Gln Leu Ala Val Met Gln Gly Ala Asn 
    50                  55                  60                  


Val Leu Val Thr Gln Arg Lys Gly Asn Phe Phe Met Gly Gly Ser Asp 
65                  70                  75                  80  


Gly Gly Tyr Thr Ile Trp 
                85      


<210>  3745
<211>  151
<212>  PRT
<213>  homo sapiens

<400>  3745

Met Ser Asp Asn Asp Asp Ile Glu Val Glu Ser Asp Ala Asp Lys Arg 
1               5                   10                  15      


Ala His His Asn Ala Leu Glu Arg Lys Arg Arg Asp His Ile Lys Asp 
            20                  25                  30          


Ser Phe His Ser Leu Arg Asp Ser Val Pro Ser Leu Gln Gly Glu Lys 
        35                  40                  45              


Ala Ser Arg Ala Gln Ile Leu Asp Lys Ala Thr Glu Tyr Ile Gln Tyr 
    50                  55                  60                  


Met Arg Arg Lys Asn His Thr His Gln Gln Asp Ile Asp Asp Leu Lys 
65                  70                  75                  80  


Arg Gln Asn Ala Leu Leu Glu Gln Gln Val Arg Ala Leu Glu Lys Ala 
                85                  90                  95      


Arg Ser Ser Ala Gln Leu Gln Thr Asn Tyr Pro Ser Ser Asp Asn Ser 
            100                 105                 110         


Leu Tyr Thr Asn Ala Lys Gly Ser Thr Ile Ser Ala Phe Asp Gly Gly 
        115                 120                 125             


Ser Asp Ser Ser Ser Glu Ser Glu Pro Glu Glu Pro Gln Ser Arg Lys 
    130                 135                 140                 


Lys Leu Arg Met Glu Ala Ser 
145                 150     


<210>  3746
<211>  362
<212>  PRT
<213>  homo sapiens

<400>  3746

Met Asp Leu His Leu Phe Asp Tyr Ser Glu Pro Gly Asn Phe Ser Asp 
1               5                   10                  15      


Ile Ser Trp Pro Cys Asn Ser Ser Asp Cys Ile Val Val Asp Thr Val 
            20                  25                  30          


Met Cys Pro Asn Met Pro Asn Lys Ser Val Leu Leu Tyr Thr Leu Ser 
        35                  40                  45              


Phe Ile Tyr Ile Phe Ile Phe Val Ile Gly Met Ile Ala Asn Ser Val 
    50                  55                  60                  


Val Val Trp Val Asn Ile Gln Ala Lys Thr Thr Gly Tyr Asp Thr His 
65                  70                  75                  80  


Cys Tyr Ile Leu Asn Leu Ala Ile Ala Asp Leu Trp Val Val Leu Thr 
                85                  90                  95      


Ile Pro Val Trp Val Val Ser Leu Val Gln His Asn Gln Trp Pro Met 
            100                 105                 110         


Gly Glu Leu Thr Cys Lys Val Thr His Leu Ile Phe Ser Ile Asn Leu 
        115                 120                 125             


Phe Gly Ser Ile Phe Phe Leu Thr Cys Met Ser Val Asp Arg Tyr Leu 
    130                 135                 140                 


Ser Ile Thr Tyr Phe Thr Asn Thr Pro Ser Ser Arg Lys Lys Met Val 
145                 150                 155                 160 


Arg Arg Val Val Cys Ile Leu Val Trp Leu Leu Ala Phe Cys Val Ser 
                165                 170                 175     


Leu Pro Asp Thr Tyr Tyr Leu Lys Thr Val Thr Ser Ala Ser Asn Asn 
            180                 185                 190         


Glu Thr Tyr Cys Arg Ser Phe Tyr Pro Glu His Ser Ile Lys Glu Trp 
        195                 200                 205             


Leu Ile Gly Met Glu Leu Val Ser Val Val Leu Gly Phe Ala Val Pro 
    210                 215                 220                 


Phe Ser Ile Ile Ala Val Phe Tyr Phe Leu Leu Ala Arg Ala Ile Ser 
225                 230                 235                 240 


Ala Ser Ser Asp Gln Glu Lys His Ser Ser Arg Lys Ile Ile Phe Ser 
                245                 250                 255     


Tyr Val Val Val Phe Leu Val Cys Trp Leu Pro Tyr His Val Ala Val 
            260                 265                 270         


Leu Leu Asp Ile Phe Ser Ile Leu His Tyr Ile Pro Phe Thr Cys Arg 
        275                 280                 285             


Leu Glu His Ala Leu Phe Thr Ala Leu His Val Thr Gln Cys Leu Ser 
    290                 295                 300                 


Leu Val His Cys Cys Val Asn Pro Val Leu Tyr Ser Phe Ile Asn Arg 
305                 310                 315                 320 


Asn Tyr Arg Tyr Glu Leu Met Lys Ala Phe Ile Phe Lys Tyr Ser Ala 
                325                 330                 335     


Lys Thr Gly Leu Thr Lys Leu Ile Asp Ala Ser Arg Val Ser Glu Thr 
            340                 345                 350         


Glu Tyr Ser Ala Leu Glu Gln Ser Thr Lys 
        355                 360         


<210>  3747
<211>  277
<212>  PRT
<213>  homo sapiens

<400>  3747

Met Glu Ala Ala Glu Thr Glu Ala Glu Ala Ala Ala Leu Glu Val Leu 
1               5                   10                  15      


Ala Glu Val Ala Gly Ile Leu Glu Pro Val Gly Leu Gln Glu Glu Ala 
            20                  25                  30          


Glu Leu Pro Ala Lys Ile Leu Val Glu Phe Val Val Asp Ser Gln Lys 
        35                  40                  45              


Lys Asp Lys Leu Leu Cys Ser Gln Leu Gln Val Ala Asp Phe Leu Gln 
    50                  55                  60                  


Asn Ile Leu Ala Gln Glu Asp Thr Ala Lys Gly Leu Asp Pro Leu Ala 
65                  70                  75                  80  


Ser Glu Asp Thr Ser Arg Gln Lys Ala Ile Ala Ala Lys Glu Gln Trp 
                85                  90                  95      


Lys Glu Leu Lys Ala Thr Tyr Arg Glu His Val Glu Ala Ile Lys Ile 
            100                 105                 110         


Gly Leu Thr Lys Ala Leu Thr Gln Met Glu Glu Ala Gln Arg Lys Arg 
        115                 120                 125             


Thr Gln Leu Arg Glu Ala Phe Glu Gln Leu Gln Ala Lys Lys Gln Met 
    130                 135                 140                 


Ala Met Glu Lys Arg Arg Ala Val Gln Asn Gln Trp Gln Leu Gln Gln 
145                 150                 155                 160 


Glu Lys His Leu Gln His Leu Ala Glu Val Ser Ala Glu Val Arg Glu 
                165                 170                 175     


Arg Lys Thr Gly Thr Gln Gln Glu Leu Asp Arg Val Phe Gln Lys Leu 
            180                 185                 190         


Gly Asn Leu Lys Gln Gln Ala Glu Gln Glu Arg Asp Lys Leu Gln Arg 
        195                 200                 205             


Tyr Gln Thr Phe Leu Gln Leu Leu Tyr Thr Leu Gln Gly Lys Leu Leu 
    210                 215                 220                 


Phe Pro Glu Ala Glu Ala Glu Ala Glu Asn Leu Pro Asp Asp Lys Pro 
225                 230                 235                 240 


Gln Gln Pro Thr Arg Pro Gln Glu Gln Ser Thr Gly Asp Thr Met Gly 
                245                 250                 255     


Arg Asp Pro Gly Val Ser Phe Lys Ala Val Gly Leu Gln Pro Ala Gly 
            260                 265                 270         


Asp Val Asn Leu Pro 
        275         


<210>  3748
<211>  919
<212>  PRT
<213>  homo sapiens

<400>  3748

Met Glu Ala Pro Glu Tyr Leu Asp Leu Asp Glu Ile Asp Phe Ser Asp 
1               5                   10                  15      


Asp Ile Ser Tyr Ser Val Thr Ser Leu Lys Thr Ile Pro Glu Leu Cys 
            20                  25                  30          


Arg Arg Cys Asp Thr Gln Asn Glu Asp Arg Ser Val Ser Ser Ser Ser 
        35                  40                  45              


Trp Asn Cys Gly Ile Ser Thr Leu Ile Thr Asn Thr Gln Lys Pro Thr 
    50                  55                  60                  


Gly Ile Ala Asp Val Tyr Ser Lys Phe Arg Pro Val Lys Arg Val Ser 
65                  70                  75                  80  


Pro Leu Lys His Gln Pro Glu Thr Leu Glu Asn Asn Glu Ser Asp Asp 
                85                  90                  95      


Gln Lys Asn Gln Lys Val Val Glu Tyr Gln Lys Gly Gly Glu Ser Asp 
            100                 105                 110         


Leu Gly Pro Gln Pro Gln Glu Leu Gly Pro Gly Asp Gly Val Gly Gly 
        115                 120                 125             


Pro Pro Gly Lys Ser Ser Glu Pro Ser Thr Ser Leu Gly Glu Leu Glu 
    130                 135                 140                 


His Tyr Asp Leu Asp Met Asp Glu Ile Leu Asp Val Pro Tyr Ile Lys 
145                 150                 155                 160 


Ser Ser Gln Gln Leu Ala Ser Phe Thr Lys Val Thr Ser Glu Lys Arg 
                165                 170                 175     


Ile Leu Gly Leu Cys Thr Thr Ile Asn Gly Leu Ser Gly Lys Ala Cys 
            180                 185                 190         


Ser Thr Gly Ser Ser Glu Ser Ser Ser Ser Asn Met Ala Pro Phe Cys 
        195                 200                 205             


Val Leu Ser Pro Val Lys Ser Pro His Leu Arg Lys Ala Ser Ala Val 
    210                 215                 220                 


Ile His Asp Gln His Lys Leu Ser Thr Glu Glu Thr Glu Ile Ser Pro 
225                 230                 235                 240 


Pro Leu Val Lys Cys Gly Ser Ala Tyr Glu Pro Glu Asn Gln Ser Lys 
                245                 250                 255     


Asp Phe Leu Asn Lys Thr Phe Ser Asp Pro His Gly Arg Lys Val Glu 
            260                 265                 270         


Lys Thr Thr Pro Asp Cys Gln Leu Arg Ala Phe His Leu Gln Ser Ser 
        275                 280                 285             


Ala Ala Glu Ser Lys Pro Glu Glu Gln Val Ser Gly Leu Asn Arg Thr 
    290                 295                 300                 


Ser Ser Gln Gly Pro Glu Glu Arg Ser Glu Tyr Leu Lys Lys Val Lys 
305                 310                 315                 320 


Ser Ile Leu Asn Ile Val Lys Glu Gly Gln Ile Ser Leu Leu Pro His 
                325                 330                 335     


Leu Ala Ala Asp Asn Leu Asp Lys Ile His Asp Glu Asn Gly Asn Asn 
            340                 345                 350         


Leu Leu His Ile Ala Ala Ser Gln Gly His Ala Glu Cys Leu Gln His 
        355                 360                 365             


Leu Thr Ser Leu Met Gly Glu Asp Cys Leu Asn Glu Arg Asn Thr Glu 
    370                 375                 380                 


Lys Leu Thr Pro Ala Gly Leu Ala Ile Lys Asn Gly Gln Leu Glu Cys 
385                 390                 395                 400 


Val Arg Trp Met Val Ser Glu Thr Glu Ala Ile Ala Glu Leu Ser Cys 
                405                 410                 415     


Ser Lys Asp Phe Pro Ser Leu Ile His Tyr Ala Gly Cys Tyr Gly Gln 
            420                 425                 430         


Glu Lys Ile Leu Leu Trp Leu Leu Gln Phe Met Gln Glu Gln Gly Ile 
        435                 440                 445             


Ser Leu Asp Glu Val Asp Gln Asp Gly Asn Ser Ala Val His Val Ala 
    450                 455                 460                 


Ser Gln His Gly Tyr Leu Gly Cys Ile Gln Thr Leu Val Glu Tyr Gly 
465                 470                 475                 480 


Ala Asn Val Thr Met Gln Asn His Ala Gly Glu Lys Pro Ser Gln Ser 
                485                 490                 495     


Ala Glu Arg Gln Gly His Thr Leu Cys Ser Arg Tyr Leu Val Val Val 
            500                 505                 510         


Glu Thr Cys Met Ser Leu Ala Ser Gln Val Val Lys Leu Thr Lys Gln 
        515                 520                 525             


Leu Lys Glu Gln Thr Val Glu Arg Val Thr Leu Gln Asn Gln Leu Gln 
    530                 535                 540                 


Gln Phe Leu Glu Ala Gln Lys Ser Glu Gly Lys Ser Leu Pro Ser Ser 
545                 550                 555                 560 


Pro Ser Ser Pro Ser Ser Pro Ala Ser Arg Lys Ser Gln Trp Lys Ser 
                565                 570                 575     


Pro Asp Ala Asp Asp Asp Ser Val Ala Lys Ser Lys Pro Gly Val Gln 
            580                 585                 590         


Glu Gly Ile Gln Val Leu Gly Ser Leu Ser Ala Ser Ser Arg Ala Arg 
        595                 600                 605             


Pro Lys Ala Lys Asp Glu Asp Ser Asp Lys Ile Leu Arg Gln Leu Leu 
    610                 615                 620                 


Gly Lys Glu Ile Ser Glu Asn Val Cys Thr Gln Glu Lys Leu Ser Leu 
625                 630                 635                 640 


Glu Phe Gln Asp Ala Gln Ala Ser Ser Arg Asn Ser Lys Lys Ile Pro 
                645                 650                 655     


Leu Glu Lys Arg Glu Leu Lys Leu Ala Arg Leu Arg Gln Leu Met Gln 
            660                 665                 670         


Arg Ser Leu Ser Glu Ser Asp Thr Asp Ser Asn Asn Ser Glu Asp Pro 
        675                 680                 685             


Lys Thr Thr Pro Val Arg Lys Ala Asp Arg Pro Arg Pro Gln Pro Ile 
    690                 695                 700                 


Val Glu Ser Val Glu Ser Met Asp Ser Ala Glu Ser Leu His Leu Met 
705                 710                 715                 720 


Ile Lys Lys His Thr Leu Ala Ser Gly Gly Arg Arg Phe Pro Phe Ser 
                725                 730                 735     


Ile Lys Ala Ser Lys Ser Leu Asp Gly His Ser Pro Ser Pro Thr Ser 
            740                 745                 750         


Glu Ser Ser Glu Pro Asp Leu Glu Ser Gln Tyr Pro Gly Ser Gly Ser 
        755                 760                 765             


Ile Pro Pro Asn Gln Pro Ser Gly Asp Pro Gln Gln Pro Ser Pro Asp 
    770                 775                 780                 


Ser Thr Ala Ala Gln Lys Val Ala Thr Ser Pro Lys Ser Ala Leu Lys 
785                 790                 795                 800 


Ser Pro Ser Ser Lys Arg Arg Thr Ser Gln Asn Leu Lys Leu Arg Val 
                805                 810                 815     


Thr Phe Glu Glu Pro Val Val Gln Met Glu Gln Pro Ser Leu Glu Leu 
            820                 825                 830         


Asn Gly Glu Lys Asp Lys Asp Lys Gly Arg Thr Leu Gln Arg Thr Ser 
        835                 840                 845             


Thr Ser Asn Glu Ser Gly Asp Gln Leu Lys Arg Pro Phe Gly Ala Phe 
    850                 855                 860                 


Arg Ser Ile Met Glu Thr Leu Ser Gly Asn Gln Asn Asn Asn Asn Asn 
865                 870                 875                 880 


Tyr Gln Ala Ala Asn Gln Leu Lys Thr Ser Thr Leu Pro Leu Thr Ser 
                885                 890                 895     


Leu Gly Arg Lys Thr Asp Ala Lys Gly Asn Pro Ala Ser Ser Ala Ser 
            900                 905                 910         


Lys Gly Lys Asn Lys Ala Ala 
        915                 


<210>  3749
<211>  1057
<212>  PRT
<213>  homo sapiens

<400>  3749

Met Ala Cys Pro Ala Leu Gly Leu Glu Ala Leu Gln Pro Leu Gln Pro 
1               5                   10                  15      


Glu Pro Pro Pro Glu Pro Ala Phe Ser Glu Ala Gln Lys Trp Ile Glu 
            20                  25                  30          


Gln Val Thr Gly Arg Ser Phe Gly Asp Lys Asp Phe Arg Thr Gly Leu 
        35                  40                  45              


Glu Asn Gly Ile Leu Leu Cys Glu Leu Leu Asn Ala Ile Lys Pro Gly 
    50                  55                  60                  


Leu Val Lys Lys Ile Asn Arg Leu Pro Thr Pro Ile Ala Gly Leu Asp 
65                  70                  75                  80  


Asn Ile Ile Leu Phe Leu Arg Gly Cys Lys Glu Leu Gly Leu Lys Glu 
                85                  90                  95      


Ser Gln Leu Phe Asp Pro Ser Asp Leu Gln Asp Thr Ser Asn Arg Val 
            100                 105                 110         


Thr Val Lys Ser Leu Asp Tyr Ser Arg Lys Leu Lys Asn Val Leu Val 
        115                 120                 125             


Thr Ile Tyr Trp Leu Gly Lys Ala Ala Asn Ser Cys Thr Ser Tyr Ser 
    130                 135                 140                 


Gly Thr Thr Leu Asn Leu Lys Glu Phe Glu Gly Leu Leu Ala Gln Met 
145                 150                 155                 160 


Arg Lys Asp Thr Asp Asp Ile Glu Ser Pro Lys Arg Ser Ile Arg Asp 
                165                 170                 175     


Ser Gly Tyr Ile Asp Cys Trp Asp Ser Glu Arg Ser Asp Ser Leu Ser 
            180                 185                 190         


Pro Pro Arg His Gly Arg Asp Asp Ser Phe Asp Ser Leu Asp Ser Phe 
        195                 200                 205             


Gly Ser Arg Ser Arg Gln Thr Pro Ser Pro Asp Val Val Leu Arg Gly 
    210                 215                 220                 


Ser Ser Asp Gly Arg Gly Ser Asp Ser Glu Ser Asp Leu Pro His Arg 
225                 230                 235                 240 


Lys Leu Pro Asp Val Lys Lys Asp Asp Met Ser Ala Arg Arg Thr Ser 
                245                 250                 255     


His Gly Glu Pro Lys Ser Ala Val Pro Phe Asn Gln Tyr Leu Pro Asn 
            260                 265                 270         


Lys Ser Asn Gln Thr Ala Tyr Val Pro Ala Pro Leu Arg Lys Lys Lys 
        275                 280                 285             


Ala Glu Arg Glu Glu Tyr Arg Lys Ser Trp Ser Thr Ala Thr Ser Pro 
    290                 295                 300                 


Leu Gly Gly Glu Arg Pro Phe Arg Tyr Gly Pro Arg Thr Pro Val Ser 
305                 310                 315                 320 


Asp Asp Ala Glu Ser Thr Ser Met Phe Asp Met Arg Cys Glu Glu Glu 
                325                 330                 335     


Ala Ala Val Gln Pro His Ser Arg Ala Arg Gln Glu Gln Leu Gln Leu 
            340                 345                 350         


Ile Asn Asn Gln Leu Arg Glu Glu Asp Asp Lys Trp Gln Asp Asp Leu 
        355                 360                 365             


Ala Arg Trp Lys Ser Arg Arg Arg Ser Val Ser Gln Asp Leu Ile Lys 
    370                 375                 380                 


Lys Glu Glu Glu Arg Lys Lys Met Glu Lys Leu Leu Ala Gly Glu Asp 
385                 390                 395                 400 


Gly Thr Ser Glu Arg Arg Lys Ser Ile Lys Thr Tyr Arg Glu Ile Val 
                405                 410                 415     


Gln Glu Lys Glu Arg Arg Glu Arg Glu Leu His Glu Ala Tyr Lys Asn 
            420                 425                 430         


Ala Arg Ser Gln Glu Glu Ala Glu Gly Ile Leu Gln Gln Tyr Ile Glu 
        435                 440                 445             


Arg Phe Thr Ile Ser Glu Ala Val Leu Glu Arg Leu Glu Met Pro Lys 
    450                 455                 460                 


Ile Leu Glu Arg Ser His Ser Thr Glu Pro Asn Leu Ser Ser Phe Leu 
465                 470                 475                 480 


Asn Asp Pro Asn Pro Met Lys Tyr Leu Arg Gln Gln Ser Leu Pro Pro 
                485                 490                 495     


Pro Lys Phe Thr Ala Thr Val Glu Thr Thr Ile Ala Arg Ala Ser Val 
            500                 505                 510         


Leu Asp Thr Ser Met Ser Ala Gly Ser Gly Ser Pro Ser Lys Thr Val 
        515                 520                 525             


Thr Pro Lys Ala Val Pro Met Leu Thr Pro Lys Pro Tyr Ser Gln Pro 
    530                 535                 540                 


Lys Asn Ser Gln Asp Val Leu Lys Thr Phe Lys Val Asp Gly Lys Val 
545                 550                 555                 560 


Ser Val Asn Gly Glu Thr Val His Arg Glu Glu Glu Lys Glu Arg Glu 
                565                 570                 575     


Cys Pro Thr Val Ala Pro Ala His Ser Leu Thr Lys Ser Gln Met Phe 
            580                 585                 590         


Glu Gly Val Ala Arg Val His Gly Ser Pro Leu Glu Leu Lys Gln Asp 
        595                 600                 605             


Asn Gly Ser Ile Glu Ile Asn Ile Lys Lys Pro Asn Ser Val Pro Gln 
    610                 615                 620                 


Glu Leu Ala Ala Thr Thr Glu Lys Thr Glu Pro Asn Ser Gln Glu Asp 
625                 630                 635                 640 


Lys Asn Asp Gly Gly Lys Ser Arg Lys Gly Asn Ile Glu Leu Ala Ser 
                645                 650                 655     


Ser Glu Pro Gln His Phe Thr Thr Thr Val Thr Arg Cys Ser Pro Thr 
            660                 665                 670         


Val Ala Phe Val Glu Phe Pro Ser Ser Pro Gln Leu Lys Asn Asp Val 
        675                 680                 685             


Ser Glu Glu Lys Asp Gln Lys Lys Pro Glu Asn Glu Met Ser Gly Lys 
    690                 695                 700                 


Val Glu Leu Val Leu Ser Gln Lys Val Val Lys Pro Lys Ser Pro Glu 
705                 710                 715                 720 


Pro Glu Ala Thr Leu Thr Phe Pro Phe Leu Asp Lys Met Pro Glu Ala 
                725                 730                 735     


Asn Gln Leu His Leu Pro Asn Leu Asn Ser Gln Val Asp Ser Pro Ser 
            740                 745                 750         


Ser Glu Lys Ser Pro Val Met Thr Pro Gln Phe Lys Phe Trp Ala Trp 
        755                 760                 765             


Asp Pro Glu Glu Glu Arg Arg Arg Gln Glu Lys Trp Gln Gln Glu Gln 
    770                 775                 780                 


Glu Arg Leu Leu Gln Glu Arg Tyr Gln Lys Glu Gln Asp Lys Leu Lys 
785                 790                 795                 800 


Glu Glu Trp Glu Lys Ala Gln Lys Glu Val Glu Glu Glu Glu Arg Arg 
                805                 810                 815     


Tyr Tyr Glu Glu Glu Arg Lys Ile Ile Glu Asp Thr Val Val Pro Phe 
            820                 825                 830         


Thr Val Ser Ser Ser Ser Ala Asp Gln Leu Ser Thr Ser Ser Ser Met 
        835                 840                 845             


Thr Glu Gly Ser Gly Thr Met Asn Lys Ile Asp Leu Gly Asn Cys Gln 
    850                 855                 860                 


Asp Glu Lys Gln Asp Arg Arg Trp Lys Lys Ser Phe Gln Gly Asp Asp 
865                 870                 875                 880 


Ser Asp Leu Leu Leu Lys Thr Arg Glu Ser Asp Arg Leu Glu Glu Lys 
                885                 890                 895     


Gly Ser Leu Thr Glu Gly Ala Leu Ala His Ser Gly Asn Pro Val Ser 
            900                 905                 910         


Lys Gly Val His Glu Asp His Gln Leu Asp Thr Glu Ala Gly Ala Pro 
        915                 920                 925             


His Cys Gly Thr Asn Pro Gln Leu Ala Gln Asp Pro Ser Gln Asn Gln 
    930                 935                 940                 


Gln Thr Ser Asn Pro Thr His Ser Ser Glu Asp Val Lys Pro Lys Thr 
945                 950                 955                 960 


Leu Pro Leu Asp Lys Ser Ile Asn His Gln Ile Glu Ser Pro Ser Glu 
                965                 970                 975     


Arg Arg Lys Ser Ile Ser Gly Lys Lys Leu Cys Ser Ser Cys Gly Leu 
            980                 985                 990         


Pro Leu Gly Lys Gly Ala Ala Met  Ile Ile Glu Thr Leu  Asn Leu Tyr 
        995                 1000                 1005             


Phe His  Ile Gln Cys Phe Arg  Cys Gly Ile Cys Lys  Gly Gln Leu 
    1010                 1015                 1020             


Gly Asp  Ala Val Ser Gly Thr  Asp Val Arg Ile Arg  Asn Gly Leu 
    1025                 1030                 1035             


Leu Asn  Cys Asn Asp Cys Tyr  Met Arg Ser Arg Ser  Ala Gly Gln 
    1040                 1045                 1050             


Pro Thr  Thr Leu 
    1055         


<210>  3750
<211>  228
<212>  PRT
<213>  homo sapiens

<400>  3750

Met Pro Val Lys Gly Gly Thr Lys Cys Ile Lys Tyr Leu Leu Phe Gly 
1               5                   10                  15      


Phe Asn Phe Ile Phe Trp Leu Ala Gly Ile Ala Val Leu Ala Ile Gly 
            20                  25                  30          


Leu Trp Leu Arg Phe Asp Ser Gln Thr Lys Ser Ile Phe Glu Gln Glu 
        35                  40                  45              


Thr Asn Asn Asn Asn Ser Ser Phe Tyr Thr Gly Val Tyr Ile Leu Ile 
    50                  55                  60                  


Gly Ala Gly Ala Leu Met Met Leu Val Gly Phe Leu Gly Cys Cys Gly 
65                  70                  75                  80  


Ala Val Gln Glu Ser Gln Cys Met Leu Gly Leu Phe Phe Gly Phe Leu 
                85                  90                  95      


Leu Val Ile Phe Ala Ile Glu Ile Ala Ala Ala Ile Trp Gly Tyr Ser 
            100                 105                 110         


His Lys Asp Glu Val Ile Lys Glu Val Gln Glu Phe Tyr Lys Asp Thr 
        115                 120                 125             


Tyr Asn Lys Leu Lys Thr Lys Asp Glu Pro Gln Arg Glu Thr Leu Lys 
    130                 135                 140                 


Ala Ile His Tyr Ala Leu Asn Cys Cys Gly Leu Ala Gly Gly Val Glu 
145                 150                 155                 160 


Gln Phe Ile Ser Asp Ile Cys Pro Lys Lys Asp Val Leu Glu Thr Phe 
                165                 170                 175     


Thr Val Lys Ser Cys Pro Asp Ala Ile Lys Glu Val Phe Asp Asn Lys 
            180                 185                 190         


Phe His Ile Ile Gly Ala Val Gly Ile Gly Ile Ala Val Val Met Ile 
        195                 200                 205             


Phe Gly Met Ile Phe Ser Met Ile Leu Cys Cys Ala Ile Arg Arg Asn 
    210                 215                 220                 


Arg Glu Met Val 
225             


<210>  3751
<211>  344
<212>  PRT
<213>  homo sapiens

<400>  3751

Met Ala Ala Ala Thr Glu Leu Asn Arg Pro Ser Ser Gly Asp Arg Asn 
1               5                   10                  15      


Leu Glu Arg Arg Cys Arg Pro Asn Leu Ser Arg Glu Val Leu Tyr Glu 
            20                  25                  30          


Ile Phe Arg Ser Leu His Thr Leu Val Gly Gln Leu Asp Leu Arg Asp 
        35                  40                  45              


Asp Val Val Lys Ile Thr Ile Asp Trp Asn Lys Leu Gln Ser Leu Ser 
    50                  55                  60                  


Ala Phe Gln Pro Ala Leu Leu Phe Ser Ala Leu Glu Gln His Ile Leu 
65                  70                  75                  80  


Tyr Leu Gln Pro Phe Leu Ala Lys Leu Gln Ser Pro Ile Lys Glu Glu 
                85                  90                  95      


Asn Thr Thr Ala Val Glu Glu Ile Gly Arg Thr Glu Met Gly Asn Lys 
            100                 105                 110         


Asn Glu Val Asn Asp Lys Phe Ser Ile Gly Asp Leu Gln Glu Glu Glu 
        115                 120                 125             


Lys His Lys Glu Ser Asp Leu Arg Asp Val Lys Lys Thr Gln Ile His 
    130                 135                 140                 


Phe Asp Pro Glu Val Val Gln Ile Lys Ala Gly Lys Ala Glu Ile Asp 
145                 150                 155                 160 


Arg Arg Ile Ser Ala Phe Ile Glu Arg Lys Gln Ala Glu Ile Asn Glu 
                165                 170                 175     


Asn Asn Val Arg Glu Phe Cys Asn Val Ile Asp Cys Asn Gln Glu Asn 
            180                 185                 190         


Ser Cys Ala Arg Thr Asp Ala Ile Phe Thr Pro Tyr Pro Gly Phe Lys 
        195                 200                 205             


Ser His Val Lys Val Ser Arg Val Val Asn Thr Tyr Gly Pro Gln Thr 
    210                 215                 220                 


Arg Pro Glu Gly Ile Pro Gly Ser Gly His Lys Pro Asn Ser Met Leu 
225                 230                 235                 240 


Arg Asp Cys Gly Asn Gln Ala Val Glu Glu Arg Leu Gln Asn Ile Glu 
                245                 250                 255     


Ala His Leu Arg Leu Gln Thr Gly Gly Pro Val Pro Arg Asp Ile Tyr 
            260                 265                 270         


Gln Arg Ile Lys Lys Leu Glu Asp Lys Ile Leu Glu Leu Glu Gly Ile 
        275                 280                 285             


Ser Pro Glu Tyr Phe Gln Ser Val Ser Phe Ser Gly Lys Arg Arg Lys 
    290                 295                 300                 


Val Gln Pro Pro Gln Gln Asn Tyr Ser Leu Ala Glu Leu Asp Glu Lys 
305                 310                 315                 320 


Ile Ser Ala Leu Lys Gln Ala Leu Leu Arg Lys Ser Arg Glu Ala Glu 
                325                 330                 335     


Ser Met Ala Thr His His Leu Pro 
            340                 


<210>  3752
<211>  341
<212>  PRT
<213>  homo sapiens

<400>  3752

Met Glu Glu Pro Gln Ser Asp Pro Ser Val Glu Pro Pro Leu Ser Gln 
1               5                   10                  15      


Glu Thr Phe Ser Asp Leu Trp Lys Leu Leu Pro Glu Asn Asn Val Leu 
            20                  25                  30          


Ser Pro Leu Pro Ser Gln Ala Met Asp Asp Leu Met Leu Ser Pro Asp 
        35                  40                  45              


Asp Ile Glu Gln Trp Phe Thr Glu Asp Pro Gly Pro Asp Glu Ala Pro 
    50                  55                  60                  


Arg Met Pro Glu Ala Ala Pro Pro Val Ala Pro Ala Pro Ala Ala Pro 
65                  70                  75                  80  


Thr Pro Ala Ala Pro Ala Pro Ala Pro Ser Trp Pro Leu Ser Ser Ser 
                85                  90                  95      


Val Pro Ser Gln Lys Thr Tyr Gln Gly Ser Tyr Gly Phe Arg Leu Gly 
            100                 105                 110         


Phe Leu His Ser Gly Thr Ala Lys Ser Val Thr Cys Thr Tyr Ser Pro 
        115                 120                 125             


Ala Leu Asn Lys Met Phe Cys Gln Leu Ala Lys Thr Cys Pro Val Gln 
    130                 135                 140                 


Leu Trp Val Asp Ser Thr Pro Pro Pro Gly Thr Arg Val Arg Ala Met 
145                 150                 155                 160 


Ala Ile Tyr Lys Gln Ser Gln His Met Thr Glu Val Val Arg Arg Cys 
                165                 170                 175     


Pro His His Glu Arg Cys Ser Asp Ser Asp Gly Leu Ala Pro Pro Gln 
            180                 185                 190         


His Leu Ile Arg Val Glu Gly Asn Leu Arg Val Glu Tyr Leu Asp Asp 
        195                 200                 205             


Arg Asn Thr Phe Arg His Ser Val Val Val Pro Tyr Glu Pro Pro Glu 
    210                 215                 220                 


Val Gly Ser Asp Cys Thr Thr Ile His Tyr Asn Tyr Met Cys Asn Ser 
225                 230                 235                 240 


Ser Cys Met Gly Gly Met Asn Arg Arg Pro Ile Leu Thr Ile Ile Thr 
                245                 250                 255     


Leu Glu Asp Ser Ser Gly Asn Leu Leu Gly Arg Asn Ser Phe Glu Val 
            260                 265                 270         


Arg Val Cys Ala Cys Pro Gly Arg Asp Arg Arg Thr Glu Glu Glu Asn 
        275                 280                 285             


Leu Arg Lys Lys Gly Glu Pro His His Glu Leu Pro Pro Gly Ser Thr 
    290                 295                 300                 


Lys Arg Ala Leu Pro Asn Asn Thr Ser Ser Ser Pro Gln Pro Lys Lys 
305                 310                 315                 320 


Lys Pro Leu Asp Gly Glu Tyr Phe Thr Leu Gln Asp Gln Thr Ser Phe 
                325                 330                 335     


Gln Lys Glu Asn Cys 
            340     


<210>  3753
<211>  261
<212>  PRT
<213>  homo sapiens

<400>  3753

Met Phe Cys Gln Leu Ala Lys Thr Cys Pro Val Gln Leu Trp Val Asp 
1               5                   10                  15      


Ser Thr Pro Pro Pro Gly Thr Arg Val Arg Ala Met Ala Ile Tyr Lys 
            20                  25                  30          


Gln Ser Gln His Met Thr Glu Val Val Arg Arg Cys Pro His His Glu 
        35                  40                  45              


Arg Cys Ser Asp Ser Asp Gly Leu Ala Pro Pro Gln His Leu Ile Arg 
    50                  55                  60                  


Val Glu Gly Asn Leu Arg Val Glu Tyr Leu Asp Asp Arg Asn Thr Phe 
65                  70                  75                  80  


Arg His Ser Val Val Val Pro Tyr Glu Pro Pro Glu Val Gly Ser Asp 
                85                  90                  95      


Cys Thr Thr Ile His Tyr Asn Tyr Met Cys Asn Ser Ser Cys Met Gly 
            100                 105                 110         


Gly Met Asn Arg Arg Pro Ile Leu Thr Ile Ile Thr Leu Glu Asp Ser 
        115                 120                 125             


Ser Gly Asn Leu Leu Gly Arg Asn Ser Phe Glu Val Arg Val Cys Ala 
    130                 135                 140                 


Cys Pro Gly Arg Asp Arg Arg Thr Glu Glu Glu Asn Leu Arg Lys Lys 
145                 150                 155                 160 


Gly Glu Pro His His Glu Leu Pro Pro Gly Ser Thr Lys Arg Ala Leu 
                165                 170                 175     


Pro Asn Asn Thr Ser Ser Ser Pro Gln Pro Lys Lys Lys Pro Leu Asp 
            180                 185                 190         


Gly Glu Tyr Phe Thr Leu Gln Ile Arg Gly Arg Glu Arg Phe Glu Met 
        195                 200                 205             


Phe Arg Glu Leu Asn Glu Ala Leu Glu Leu Lys Asp Ala Gln Ala Gly 
    210                 215                 220                 


Lys Glu Pro Gly Gly Ser Arg Ala His Ser Ser His Leu Lys Ser Lys 
225                 230                 235                 240 


Lys Gly Gln Ser Thr Ser Arg His Lys Lys Leu Met Phe Lys Thr Glu 
                245                 250                 255     


Gly Pro Asp Ser Asp 
            260     


<210>  3754
<211>  209
<212>  PRT
<213>  homo sapiens

<400>  3754

Met Phe Cys Gln Leu Ala Lys Thr Cys Pro Val Gln Leu Trp Val Asp 
1               5                   10                  15      


Ser Thr Pro Pro Pro Gly Thr Arg Val Arg Ala Met Ala Ile Tyr Lys 
            20                  25                  30          


Gln Ser Gln His Met Thr Glu Val Val Arg Arg Cys Pro His His Glu 
        35                  40                  45              


Arg Cys Ser Asp Ser Asp Gly Leu Ala Pro Pro Gln His Leu Ile Arg 
    50                  55                  60                  


Val Glu Gly Asn Leu Arg Val Glu Tyr Leu Asp Asp Arg Asn Thr Phe 
65                  70                  75                  80  


Arg His Ser Val Val Val Pro Tyr Glu Pro Pro Glu Val Gly Ser Asp 
                85                  90                  95      


Cys Thr Thr Ile His Tyr Asn Tyr Met Cys Asn Ser Ser Cys Met Gly 
            100                 105                 110         


Gly Met Asn Arg Arg Pro Ile Leu Thr Ile Ile Thr Leu Glu Asp Ser 
        115                 120                 125             


Ser Gly Asn Leu Leu Gly Arg Asn Ser Phe Glu Val Arg Val Cys Ala 
    130                 135                 140                 


Cys Pro Gly Arg Asp Arg Arg Thr Glu Glu Glu Asn Leu Arg Lys Lys 
145                 150                 155                 160 


Gly Glu Pro His His Glu Leu Pro Pro Gly Ser Thr Lys Arg Ala Leu 
                165                 170                 175     


Pro Asn Asn Thr Ser Ser Ser Pro Gln Pro Lys Lys Lys Pro Leu Asp 
            180                 185                 190         


Gly Glu Tyr Phe Thr Leu Gln Asp Gln Thr Ser Phe Gln Lys Glu Asn 
        195                 200                 205             


Cys 
    


<210>  3755
<211>  955
<212>  PRT
<213>  homo sapiens

<400>  3755

Met Ala Thr Gly Leu Gly Glu Pro Val Tyr Gly Leu Ser Glu Asp Glu 
1               5                   10                  15      


Gly Glu Ser Arg Ile Leu Arg Val Lys Val Val Ser Gly Ile Asp Leu 
            20                  25                  30          


Ala Lys Lys Asp Ile Phe Gly Ala Ser Asp Pro Tyr Val Lys Leu Ser 
        35                  40                  45              


Leu Tyr Val Ala Asp Glu Asn Arg Glu Leu Ala Leu Val Gln Thr Lys 
    50                  55                  60                  


Thr Ile Lys Lys Thr Leu Asn Pro Lys Trp Asn Glu Glu Phe Tyr Phe 
65                  70                  75                  80  


Arg Val Asn Pro Ser Asn His Arg Leu Leu Phe Glu Val Phe Asp Glu 
                85                  90                  95      


Asn Arg Leu Thr Arg Asp Asp Phe Leu Gly Gln Val Asp Val Pro Leu 
            100                 105                 110         


Ser His Leu Pro Thr Glu Asp Pro Thr Met Glu Arg Pro Tyr Thr Phe 
        115                 120                 125             


Lys Asp Phe Leu Leu Arg Pro Arg Ser His Lys Ser Arg Val Lys Gly 
    130                 135                 140                 


Phe Leu Arg Leu Lys Met Ala Tyr Met Pro Lys Asn Gly Gly Gln Asp 
145                 150                 155                 160 


Glu Glu Asn Ser Asp Gln Arg Asp Asp Met Glu His Gly Trp Glu Val 
                165                 170                 175     


Val Asp Ser Asn Asp Ser Ala Ser Gln His Gln Glu Glu Leu Pro Pro 
            180                 185                 190         


Pro Pro Leu Pro Pro Gly Trp Glu Glu Lys Val Asp Asn Leu Gly Arg 
        195                 200                 205             


Thr Tyr Tyr Val Asn His Asn Asn Arg Thr Thr Gln Trp His Arg Pro 
    210                 215                 220                 


Ser Leu Met Asp Val Ser Ser Glu Ser Asp Asn Asn Ile Arg Gln Ile 
225                 230                 235                 240 


Asn Gln Glu Ala Ala His Arg Arg Phe Arg Ser Arg Arg His Ile Ser 
                245                 250                 255     


Glu Asp Leu Glu Pro Glu Pro Ser Glu Gly Gly Asp Val Pro Glu Pro 
            260                 265                 270         


Trp Glu Thr Ile Ser Glu Glu Val Asn Ile Ala Gly Asp Ser Leu Gly 
        275                 280                 285             


Leu Ala Leu Pro Pro Pro Pro Ala Ser Pro Gly Ser Arg Thr Ser Pro 
    290                 295                 300                 


Gln Glu Leu Ser Glu Glu Leu Ser Arg Arg Leu Gln Ile Thr Pro Asp 
305                 310                 315                 320 


Ser Asn Gly Glu Gln Phe Ser Ser Leu Ile Gln Arg Glu Pro Ser Ser 
                325                 330                 335     


Arg Leu Arg Ser Cys Ser Val Thr Asp Ala Val Ala Glu Gln Gly His 
            340                 345                 350         


Leu Pro Pro Pro Ser Val Ala Tyr Val His Thr Thr Pro Gly Leu Pro 
        355                 360                 365             


Ser Gly Trp Glu Glu Arg Lys Asp Ala Lys Gly Arg Thr Tyr Tyr Val 
    370                 375                 380                 


Asn His Asn Asn Arg Thr Thr Thr Trp Thr Arg Pro Ile Met Gln Leu 
385                 390                 395                 400 


Ala Glu Asp Gly Ala Ser Gly Ser Ala Thr Asn Ser Asn Asn His Leu 
                405                 410                 415     


Ile Glu Pro Gln Ile Arg Arg Pro Arg Ser Leu Ser Ser Pro Thr Val 
            420                 425                 430         


Thr Leu Ser Ala Pro Leu Glu Gly Ala Lys Asp Ser Pro Val Arg Arg 
        435                 440                 445             


Ala Val Lys Asp Thr Leu Ser Asn Pro Gln Ser Pro Gln Pro Ser Pro 
    450                 455                 460                 


Tyr Asn Ser Pro Lys Pro Gln His Lys Val Thr Gln Ser Phe Leu Pro 
465                 470                 475                 480 


Pro Gly Trp Glu Met Arg Ile Ala Pro Asn Gly Arg Pro Phe Phe Ile 
                485                 490                 495     


Asp His Asn Thr Lys Thr Thr Thr Trp Glu Asp Pro Arg Leu Lys Phe 
            500                 505                 510         


Pro Val His Met Arg Ser Lys Thr Ser Leu Asn Pro Asn Asp Leu Gly 
        515                 520                 525             


Pro Leu Pro Pro Gly Trp Glu Glu Arg Ile His Leu Asp Gly Arg Thr 
    530                 535                 540                 


Phe Tyr Ile Asp His Asn Ser Lys Ile Thr Gln Trp Glu Asp Pro Arg 
545                 550                 555                 560 


Leu Gln Asn Pro Ala Ile Thr Gly Pro Ala Val Pro Tyr Ser Arg Glu 
                565                 570                 575     


Phe Lys Gln Lys Tyr Asp Tyr Phe Arg Lys Lys Leu Lys Lys Pro Ala 
            580                 585                 590         


Asp Ile Pro Asn Arg Phe Glu Met Lys Leu His Arg Asn Asn Ile Phe 
        595                 600                 605             


Glu Glu Ser Tyr Arg Arg Ile Met Ser Val Lys Arg Pro Asp Val Leu 
    610                 615                 620                 


Lys Ala Arg Leu Trp Ile Glu Phe Glu Ser Glu Lys Gly Leu Asp Tyr 
625                 630                 635                 640 


Gly Gly Val Ala Arg Glu Trp Phe Phe Leu Leu Ser Lys Glu Met Phe 
                645                 650                 655     


Asn Pro Tyr Tyr Gly Leu Phe Glu Tyr Ser Ala Thr Asp Asn Tyr Thr 
            660                 665                 670         


Leu Gln Ile Asn Pro Asn Ser Gly Leu Cys Asn Glu Asp His Leu Ser 
        675                 680                 685             


Tyr Phe Thr Phe Ile Gly Arg Val Ala Gly Leu Ala Val Phe His Gly 
    690                 695                 700                 


Lys Leu Leu Asp Gly Phe Phe Ile Arg Pro Phe Tyr Lys Met Met Leu 
705                 710                 715                 720 


Gly Lys Gln Ile Thr Leu Asn Asp Met Glu Ser Val Asp Ser Glu Tyr 
                725                 730                 735     


Tyr Asn Ser Leu Lys Trp Ile Leu Glu Asn Asp Pro Thr Glu Leu Asp 
            740                 745                 750         


Leu Met Phe Cys Ile Asp Glu Glu Asn Phe Gly Gln Thr Tyr Gln Val 
        755                 760                 765             


Asp Leu Lys Pro Asn Gly Ser Glu Ile Met Val Thr Asn Glu Asn Lys 
    770                 775                 780                 


Arg Glu Tyr Ile Asp Leu Val Ile Gln Trp Arg Phe Val Asn Arg Val 
785                 790                 795                 800 


Gln Lys Gln Met Asn Ala Phe Leu Glu Gly Phe Thr Glu Leu Leu Pro 
                805                 810                 815     


Ile Asp Leu Ile Lys Ile Phe Asp Glu Asn Glu Leu Glu Leu Leu Met 
            820                 825                 830         


Cys Gly Leu Gly Asp Val Asp Val Asn Asp Trp Arg Gln His Ser Ile 
        835                 840                 845             


Tyr Lys Asn Gly Tyr Cys Pro Asn His Pro Val Ile Gln Trp Phe Trp 
    850                 855                 860                 


Lys Ala Val Leu Leu Met Asp Ala Glu Lys Arg Ile Arg Leu Leu Gln 
865                 870                 875                 880 


Phe Val Thr Gly Thr Ser Arg Val Pro Met Asn Gly Phe Ala Glu Leu 
                885                 890                 895     


Tyr Gly Ser Asn Gly Pro Gln Leu Phe Thr Ile Glu Gln Trp Gly Ser 
            900                 905                 910         


Pro Glu Lys Leu Pro Arg Ala His Thr Cys Phe Asn Arg Leu Asp Leu 
        915                 920                 925             


Pro Pro Tyr Glu Thr Phe Glu Asp Leu Arg Glu Lys Leu Leu Met Ala 
    930                 935                 940                 


Val Glu Asn Ala Gln Gly Phe Glu Gly Val Asp 
945                 950                 955 


<210>  3756
<211>  453
<212>  PRT
<213>  homo sapiens

<400>  3756

Met Gly Arg Thr Arg Glu Ala Gly Cys Val Ala Ala Gly Val Val Ile 
1               5                   10                  15      


Gly Ala Gly Ala Cys Tyr Cys Val Tyr Arg Leu Ala Trp Gly Arg Asp 
            20                  25                  30          


Glu Asn Glu Lys Ile Trp Asp Glu Asp Glu Glu Ser Thr Asp Thr Ser 
        35                  40                  45              


Glu Ile Gly Val Glu Thr Val Lys Gly Ala Lys Thr Asn Ala Gly Ala 
    50                  55                  60                  


Gly Ser Gly Ala Lys Leu Gln Gly Asp Ser Glu Val Lys Pro Glu Val 
65                  70                  75                  80  


Ser Leu Gly Leu Glu Asp Cys Pro Gly Val Lys Glu Lys Ala His Ser 
                85                  90                  95      


Gly Ser His Ser Gly Gly Gly Leu Glu Ala Lys Ala Lys Ala Leu Phe 
            100                 105                 110         


Asn Thr Leu Lys Glu Gln Ala Ser Ala Lys Ala Gly Lys Gly Ala Arg 
        115                 120                 125             


Val Gly Thr Ile Ser Gly Asn Arg Thr Leu Ala Pro Ser Leu Pro Cys 
    130                 135                 140                 


Pro Gly Gly Arg Gly Gly Gly Cys His Pro Thr Arg Ser Gly Ser Arg 
145                 150                 155                 160 


Ala Gly Gly Arg Ala Ser Gly Lys Ser Lys Gly Lys Ala Arg Ser Lys 
                165                 170                 175     


Ser Thr Arg Ala Pro Ala Thr Thr Trp Pro Val Arg Arg Gly Lys Phe 
            180                 185                 190         


Asn Phe Pro Tyr Lys Ile Asp Asp Ile Leu Ser Ala Pro Asp Leu Gln 
        195                 200                 205             


Lys Val Leu Asn Ile Leu Glu Arg Thr Asn Asp Pro Phe Ile Gln Glu 
    210                 215                 220                 


Val Ala Leu Val Thr Leu Gly Asn Asn Ala Ala Tyr Ser Phe Asn Gln 
225                 230                 235                 240 


Asn Ala Ile Arg Glu Leu Gly Gly Val Pro Ile Ile Ala Lys Leu Ile 
                245                 250                 255     


Lys Thr Lys Asp Pro Ile Ile Arg Glu Lys Thr Tyr Asn Ala Leu Asn 
            260                 265                 270         


Asn Leu Ser Val Asn Ala Glu Asn Gln Gly Lys Ile Lys Thr Tyr Ile 
        275                 280                 285             


Ser Gln Val Cys Asp Asp Thr Met Val Cys Arg Leu Asp Ser Ala Val 
    290                 295                 300                 


Gln Met Ala Gly Leu Arg Leu Leu Thr Asn Met Thr Val Thr Asn His 
305                 310                 315                 320 


Tyr Gln His Leu Leu Ser Tyr Ser Phe Pro Asp Phe Phe Ala Leu Leu 
                325                 330                 335     


Phe Leu Gly Asn His Phe Thr Lys Ile Gln Ile Met Lys Leu Ile Ile 
            340                 345                 350         


Asn Phe Thr Glu Asn Pro Ala Met Thr Arg Glu Leu Val Ser Cys Lys 
        355                 360                 365             


Val Pro Ser Glu Leu Ile Ser Leu Phe Asn Lys Glu Trp Asp Arg Glu 
    370                 375                 380                 


Ile Leu Leu Asn Ile Leu Thr Leu Phe Glu Asn Ile Asn Asp Asn Ile 
385                 390                 395                 400 


Lys Asn Glu Gly Leu Ala Ser Ser Arg Lys Glu Phe Ser Arg Ser Ser 
                405                 410                 415     


Leu Phe Phe Leu Phe Lys Glu Ser Gly Val Cys Val Lys Lys Ile Lys 
            420                 425                 430         


Ala Leu Ala Asn His Asn Asp Leu Val Val Lys Val Lys Val Leu Lys 
        435                 440                 445             


Val Leu Thr Lys Leu 
    450             


<210>  3757
<211>  718
<212>  PRT
<213>  homo sapiens

<400>  3757

Met Ser Val Ser Gly Lys Lys Glu Phe Asp Val Lys Gln Ile Leu Arg 
1               5                   10                  15      


Leu Arg Trp Arg Trp Phe Ser His Pro Phe Gln Gly Ser Thr Asn Thr 
            20                  25                  30          


Gly Ser Cys Leu Gln Gln Glu Gly Tyr Glu His Arg Gly Thr Pro Val 
        35                  40                  45              


Gln Gly Arg Leu Lys Ser His Ser Arg Asp Arg Asn Gly Leu Lys Lys 
    50                  55                  60                  


Ser Asn Ser Pro Val His His Asn Ile Leu Ala Pro Val Pro Gly Pro 
65                  70                  75                  80  


Ala Pro Ala His Gln Arg Ala Val Gln Asn Leu Gln Gln His Asn Leu 
                85                  90                  95      


Ile Val His Phe Gln Ala Asn Glu Asp Thr Pro Lys Ser Val Pro Glu 
            100                 105                 110         


Lys Asn Leu Phe Lys Glu Ala Cys Glu Lys Arg Ala Gln Asp Leu Glu 
        115                 120                 125             


Met Met Ala Asp Asp Asn Ile Glu Asp Ser Thr Ala Arg Leu Asp Thr 
    130                 135                 140                 


Gln His Ser Glu Asp Met Asn Ala Thr Arg Ser Glu Glu Gln Phe His 
145                 150                 155                 160 


Val Ile Asn His Ala Glu Gln Thr Leu Arg Lys Met Glu Asn Tyr Leu 
                165                 170                 175     


Lys Glu Lys Gln Leu Cys Asp Val Leu Leu Ile Ala Gly His Leu Arg 
            180                 185                 190         


Ile Pro Ala His Arg Leu Val Leu Ser Ala Val Ser Asp Tyr Phe Ala 
        195                 200                 205             


Ala Met Phe Thr Asn Asp Val Leu Glu Ala Lys Gln Glu Glu Val Arg 
    210                 215                 220                 


Met Glu Gly Val Asp Pro Asn Ala Leu Asn Ser Leu Val Gln Tyr Ala 
225                 230                 235                 240 


Tyr Thr Gly Val Leu Gln Leu Lys Glu Asp Thr Ile Glu Ser Leu Leu 
                245                 250                 255     


Ala Ala Ala Cys Leu Leu Gln Leu Thr Gln Val Ile Asp Val Cys Ser 
            260                 265                 270         


Asn Phe Leu Ile Lys Gln Leu His Pro Ser Asn Cys Leu Gly Ile Arg 
        275                 280                 285             


Ser Phe Gly Asp Ala Gln Gly Cys Thr Glu Leu Leu Asn Val Ala His 
    290                 295                 300                 


Lys Tyr Thr Met Glu His Phe Ile Glu Val Ile Lys Asn Gln Glu Phe 
305                 310                 315                 320 


Leu Leu Leu Pro Ala Asn Glu Ile Ser Lys Leu Leu Cys Ser Asp Asp 
                325                 330                 335     


Ile Asn Val Pro Asp Glu Glu Thr Ile Phe His Ala Leu Met Gln Trp 
            340                 345                 350         


Val Gly His Asp Val Gln Asn Arg Gln Gly Glu Leu Gly Met Leu Leu 
        355                 360                 365             


Ser Tyr Ile Arg Leu Pro Leu Leu Pro Pro Gln Leu Leu Ala Asp Leu 
    370                 375                 380                 


Glu Thr Ser Ser Met Phe Thr Gly Asp Leu Glu Cys Gln Lys Leu Leu 
385                 390                 395                 400 


Met Glu Ala Met Lys Tyr His Leu Leu Pro Glu Arg Arg Ser Met Met 
                405                 410                 415     


Gln Ser Pro Arg Thr Lys Pro Arg Lys Ser Thr Val Gly Ala Leu Tyr 
            420                 425                 430         


Ala Val Gly Gly Met Asp Ala Met Lys Gly Thr Thr Thr Ile Glu Lys 
        435                 440                 445             


Tyr Asp Leu Arg Thr Asn Ser Trp Leu His Ile Gly Thr Met Asn Gly 
    450                 455                 460                 


Arg Arg Leu Gln Phe Gly Val Ala Val Ile Asp Asn Lys Leu Tyr Val 
465                 470                 475                 480 


Val Gly Gly Arg Asp Gly Leu Lys Thr Leu Asn Thr Val Glu Cys Phe 
                485                 490                 495     


Asn Pro Val Gly Lys Ile Trp Thr Val Met Pro Pro Met Ser Thr His 
            500                 505                 510         


Arg His Gly Leu Gly Val Ala Thr Leu Glu Gly Pro Met Tyr Ala Val 
        515                 520                 525             


Gly Gly His Asp Gly Trp Ser Tyr Leu Asn Thr Val Glu Arg Trp Asp 
    530                 535                 540                 


Pro Glu Gly Arg Gln Trp Asn Tyr Val Ala Ser Met Ser Thr Pro Arg 
545                 550                 555                 560 


Ser Thr Val Gly Val Val Ala Leu Asn Asn Lys Leu Tyr Ala Ile Gly 
                565                 570                 575     


Gly Arg Asp Gly Ser Ser Cys Leu Lys Ser Met Glu Tyr Phe Asp Pro 
            580                 585                 590         


His Thr Asn Lys Trp Ser Leu Cys Ala Pro Met Ser Lys Arg Arg Gly 
        595                 600                 605             


Gly Val Gly Val Ala Thr Tyr Asn Gly Phe Leu Tyr Val Val Gly Gly 
    610                 615                 620                 


His Asp Ala Pro Ala Ser Asn His Cys Ser Arg Leu Ser Asp Cys Val 
625                 630                 635                 640 


Glu Arg Tyr Asp Pro Lys Gly Asp Ser Trp Ser Thr Val Ala Pro Leu 
                645                 650                 655     


Ser Val Pro Arg Asp Ala Val Ala Val Cys Pro Leu Gly Asp Lys Leu 
            660                 665                 670         


Tyr Val Val Gly Gly Tyr Asp Gly His Thr Tyr Leu Asn Thr Val Glu 
        675                 680                 685             


Ser Tyr Asp Ala Gln Arg Asn Glu Trp Lys Glu Glu Val Pro Val Asn 
    690                 695                 700                 


Ile Gly Arg Ala Gly Ala Cys Val Val Val Val Lys Leu Pro 
705                 710                 715             


<210>  3758
<211>  617
<212>  PRT
<213>  homo sapiens

<400>  3758

Met Lys Val Ser Leu Gly Asn Gly Glu Met Gly Val Ser Ala His Leu 
1               5                   10                  15      


Gln Pro Cys Lys Ala Gly Thr Thr Arg Phe Phe Thr Ser Asn Thr His 
            20                  25                  30          


Ser Ser Val Val Leu Gln Gly Phe Asp Gln Leu Arg Ile Glu Gly Leu 
        35                  40                  45              


Leu Cys Asp Val Thr Leu Val Pro Gly Asp Gly Asp Glu Ile Phe Pro 
    50                  55                  60                  


Val His Arg Ala Met Met Ala Ser Ala Ser Asp Tyr Phe Lys Ala Met 
65                  70                  75                  80  


Phe Thr Gly Gly Met Lys Glu Gln Asp Leu Met Cys Ile Lys Leu His 
                85                  90                  95      


Gly Val Asn Lys Val Gly Leu Lys Lys Ile Ile Asp Phe Ile Tyr Thr 
            100                 105                 110         


Ala Lys Leu Ser Leu Asn Met Asp Asn Leu Gln Asp Thr Leu Glu Ala 
        115                 120                 125             


Ala Ser Phe Leu Gln Ile Leu Pro Val Leu Asp Phe Cys Lys Val Phe 
    130                 135                 140                 


Leu Ile Ser Gly Val Ser Leu Asp Asn Cys Val Glu Val Gly Arg Ile 
145                 150                 155                 160 


Ala Asn Thr Tyr Asn Leu Ile Glu Val Asp Lys Tyr Val Asn Asn Phe 
                165                 170                 175     


Ile Leu Lys Asn Phe Pro Ala Leu Leu Ser Thr Gly Glu Phe Leu Lys 
            180                 185                 190         


Leu Pro Phe Glu Arg Leu Ala Phe Val Leu Ser Ser Asn Ser Leu Lys 
        195                 200                 205             


His Cys Thr Glu Leu Glu Leu Phe Lys Ala Ala Cys Arg Trp Leu Arg 
    210                 215                 220                 


Leu Glu Asp Pro Arg Met Asp Tyr Ala Ala Lys Leu Met Lys Asn Ile 
225                 230                 235                 240 


Arg Phe Pro Leu Met Thr Pro Gln Asp Leu Ile Asn Tyr Val Gln Thr 
                245                 250                 255     


Val Asp Phe Met Arg Thr Asp Asn Thr Cys Val Asn Leu Leu Leu Glu 
            260                 265                 270         


Ala Ser Asn Tyr Gln Met Met Pro Tyr Met Gln Pro Val Met Gln Ser 
        275                 280                 285             


Asp Arg Thr Ala Ile Arg Ser Asp Ser Thr His Leu Val Thr Leu Gly 
    290                 295                 300                 


Gly Val Leu Arg Gln Gln Leu Val Val Ser Lys Glu Leu Arg Met Tyr 
305                 310                 315                 320 


Asp Glu Arg Ala Gln Glu Trp Arg Ser Leu Ala Pro Met Asp Ala Pro 
                325                 330                 335     


Arg Tyr Gln His Gly Ile Ala Val Ile Gly Asn Phe Leu Tyr Val Val 
            340                 345                 350         


Gly Gly Gln Ser Asn Tyr Asp Thr Lys Gly Lys Thr Ala Val Asp Thr 
        355                 360                 365             


Val Phe Arg Phe Asp Pro Arg Tyr Asn Lys Trp Met Gln Val Ala Ser 
    370                 375                 380                 


Leu Asn Glu Lys Arg Thr Phe Phe His Leu Ser Ala Leu Lys Gly His 
385                 390                 395                 400 


Leu Tyr Ala Val Gly Gly Arg Ser Ala Ala Gly Glu Leu Ala Thr Val 
                405                 410                 415     


Glu Cys Tyr Asn Pro Arg Met Asn Glu Trp Ser Tyr Val Ala Lys Met 
            420                 425                 430         


Ser Glu Pro His Tyr Gly His Ala Gly Thr Val Tyr Gly Gly Leu Met 
        435                 440                 445             


Tyr Ile Ser Gly Gly Ile Thr His Asp Thr Phe Gln Asn Glu Leu Met 
    450                 455                 460                 


Cys Phe Asp Pro Asp Thr Asp Lys Trp Met Gln Lys Ala Pro Met Thr 
465                 470                 475                 480 


Thr Val Arg Gly Leu His Cys Met Cys Thr Val Gly Asp Lys Leu Tyr 
                485                 490                 495     


Val Ile Gly Gly Asn His Phe Arg Gly Thr Ser Asp Tyr Asp Asp Val 
            500                 505                 510         


Leu Ser Cys Glu Tyr Tyr Ser Pro Thr Leu Asp Gln Trp Thr Pro Ile 
        515                 520                 525             


Ala Ala Met Leu Arg Gly Gln Ser Asp Val Gly Val Ala Val Phe Glu 
    530                 535                 540                 


Asn Lys Ile Tyr Val Val Gly Gly Tyr Ser Trp Asn Asn Arg Cys Met 
545                 550                 555                 560 


Val Glu Ile Val Gln Lys Tyr Asp Pro Glu Lys Asp Glu Trp His Lys 
                565                 570                 575     


Val Phe Asp Leu Pro Glu Ser Leu Gly Gly Ile Arg Ala Cys Thr Leu 
            580                 585                 590         


Thr Val Phe Pro Pro Glu Glu Asn Pro Gly Ser Pro Ser Arg Glu Ser 
        595                 600                 605             


Pro Leu Ser Ala Pro Ser Asp His Ser 
    610                 615         


<210>  3759
<211>  403
<212>  PRT
<213>  homo sapiens

<400>  3759

Met Thr Thr Leu Ala Gly Ala Val Pro Arg Met Met Arg Pro Gly Pro 
1               5                   10                  15      


Gly Gln Asn Tyr Pro Arg Ser Gly Phe Pro Leu Glu Val Ser Thr Pro 
            20                  25                  30          


Leu Gly Gln Gly Arg Val Asn Gln Leu Gly Gly Val Phe Ile Asn Gly 
        35                  40                  45              


Arg Pro Leu Pro Asn His Ile Arg His Lys Ile Val Glu Met Ala His 
    50                  55                  60                  


His Gly Ile Arg Pro Cys Val Ile Ser Arg Gln Leu Arg Val Ser His 
65                  70                  75                  80  


Gly Cys Val Ser Lys Ile Leu Cys Arg Tyr Gln Glu Thr Gly Ser Ile 
                85                  90                  95      


Arg Pro Gly Ala Ile Gly Gly Ser Lys Pro Lys Gln Val Thr Thr Pro 
            100                 105                 110         


Asp Val Glu Lys Lys Ile Glu Glu Tyr Lys Arg Glu Asn Pro Gly Met 
        115                 120                 125             


Phe Ser Trp Glu Ile Arg Asp Lys Leu Leu Lys Asp Ala Val Cys Asp 
    130                 135                 140                 


Arg Asn Thr Val Pro Ser Val Ser Ser Ile Ser Arg Ile Leu Arg Ser 
145                 150                 155                 160 


Lys Phe Gly Lys Gly Glu Glu Glu Glu Ala Asp Leu Glu Arg Lys Glu 
                165                 170                 175     


Ala Glu Glu Ser Glu Lys Lys Ala Lys His Ser Ile Asp Gly Ile Leu 
            180                 185                 190         


Ser Glu Arg Ala Ser Ala Pro Gln Ser Asp Glu Gly Ser Asp Ile Asp 
        195                 200                 205             


Ser Glu Pro Asp Leu Pro Leu Lys Arg Lys Gln Arg Arg Ser Arg Thr 
    210                 215                 220                 


Thr Phe Thr Ala Glu Gln Leu Glu Glu Leu Glu Arg Ala Phe Glu Arg 
225                 230                 235                 240 


Thr His Tyr Pro Asp Ile Tyr Thr Arg Glu Glu Leu Ala Gln Arg Ala 
                245                 250                 255     


Lys Leu Thr Glu Ala Arg Val Gln Val Trp Phe Ser Asn Arg Arg Ala 
            260                 265                 270         


Arg Trp Arg Lys Gln Ala Gly Ala Asn Gln Leu Met Ala Phe Asn His 
        275                 280                 285             


Leu Ile Pro Gly Gly Phe Pro Pro Thr Ala Met Pro Thr Leu Pro Thr 
    290                 295                 300                 


Tyr Gln Leu Ser Glu Thr Ser Tyr Gln Pro Thr Ser Ile Pro Gln Ala 
305                 310                 315                 320 


Val Ser Asp Pro Ser Ser Thr Val His Arg Pro Gln Pro Leu Pro Pro 
                325                 330                 335     


Ser Thr Val His Gln Ser Thr Ile Pro Ser Asn Pro Asp Ser Ser Ser 
            340                 345                 350         


Ala Tyr Cys Leu Pro Ser Thr Arg His Gly Phe Ser Ser Tyr Thr Asp 
        355                 360                 365             


Ser Phe Val Pro Pro Ser Gly Pro Ser Asn Pro Met Asn Pro Thr Ile 
    370                 375                 380                 


Gly Asn Gly Leu Ser Pro Gln Val Pro Phe Ile Ile Ser Ser Gln Ile 
385                 390                 395                 400 


Ser Arg Lys 
            


<210>  3760
<211>  483
<212>  PRT
<213>  homo sapiens

<400>  3760

Met Thr Thr Leu Ala Gly Ala Val Pro Arg Met Met Arg Pro Gly Pro 
1               5                   10                  15      


Gly Gln Asn Tyr Pro Arg Ser Gly Phe Pro Leu Glu Val Ser Thr Pro 
            20                  25                  30          


Leu Gly Gln Gly Arg Val Asn Gln Leu Gly Gly Val Phe Ile Asn Gly 
        35                  40                  45              


Arg Pro Leu Pro Asn His Ile Arg His Lys Ile Val Glu Met Ala His 
    50                  55                  60                  


His Gly Ile Arg Pro Cys Val Ile Ser Arg Gln Leu Arg Val Ser His 
65                  70                  75                  80  


Gly Cys Val Ser Lys Ile Leu Cys Arg Tyr Gln Glu Thr Gly Ser Ile 
                85                  90                  95      


Arg Pro Gly Ala Ile Gly Gly Ser Lys Pro Lys Val Thr Thr Pro Asp 
            100                 105                 110         


Val Glu Lys Lys Ile Glu Glu Tyr Lys Arg Glu Asn Pro Gly Met Phe 
        115                 120                 125             


Ser Trp Glu Ile Arg Asp Lys Leu Leu Lys Asp Ala Val Cys Asp Arg 
    130                 135                 140                 


Asn Thr Val Pro Ser Val Ser Ser Ile Ser Arg Ile Leu Arg Ser Lys 
145                 150                 155                 160 


Phe Gly Lys Gly Glu Glu Glu Glu Ala Asp Leu Glu Arg Lys Glu Ala 
                165                 170                 175     


Glu Glu Ser Glu Lys Lys Ala Lys His Ser Ile Asp Gly Ile Leu Ser 
            180                 185                 190         


Glu Arg Ala Ser Ala Pro Gln Ser Asp Glu Gly Ser Asp Ile Asp Ser 
        195                 200                 205             


Glu Pro Asp Leu Pro Leu Lys Arg Lys Gln Arg Arg Ser Arg Thr Thr 
    210                 215                 220                 


Phe Thr Ala Glu Gln Leu Glu Glu Leu Glu Arg Ala Phe Glu Arg Thr 
225                 230                 235                 240 


His Tyr Pro Asp Ile Tyr Thr Arg Glu Glu Leu Ala Gln Arg Ala Lys 
                245                 250                 255     


Leu Thr Glu Ala Arg Val Gln Val Trp Phe Ser Asn Arg Arg Ala Arg 
            260                 265                 270         


Trp Arg Lys Gln Ala Gly Ala Asn Gln Leu Met Ala Phe Asn His Leu 
        275                 280                 285             


Ile Pro Gly Gly Phe Pro Pro Thr Ala Met Pro Thr Leu Pro Thr Tyr 
    290                 295                 300                 


Gln Leu Ser Glu Thr Ser Tyr Gln Pro Thr Ser Ile Pro Gln Ala Val 
305                 310                 315                 320 


Ser Asp Pro Ser Ser Thr Val His Arg Pro Gln Pro Leu Pro Pro Ser 
                325                 330                 335     


Thr Val His Gln Ser Thr Ile Pro Ser Asn Pro Asp Ser Ser Ser Ala 
            340                 345                 350         


Tyr Cys Leu Pro Ser Thr Arg His Gly Phe Ser Ser Tyr Thr Asp Ser 
        355                 360                 365             


Phe Val Pro Pro Ser Gly Pro Ser Asn Pro Met Asn Pro Thr Ile Gly 
    370                 375                 380                 


Asn Gly Leu Ser Pro Gln Val Met Gly Leu Leu Thr Asn His Gly Gly 
385                 390                 395                 400 


Val Pro His Gln Pro Gln Thr Asp Tyr Ala Leu Ser Pro Leu Thr Gly 
                405                 410                 415     


Gly Leu Glu Pro Thr Thr Thr Val Ser Ala Ser Cys Ser Gln Arg Leu 
            420                 425                 430         


Asp His Met Lys Ser Leu Asp Ser Leu Pro Thr Ser Gln Ser Tyr Cys 
        435                 440                 445             


Pro Pro Thr Tyr Ser Thr Thr Gly Tyr Ser Met Asp Pro Val Thr Gly 
    450                 455                 460                 


Tyr Gln Tyr Gly Gln Tyr Gly Gln Ser Ala Phe His Tyr Leu Lys Pro 
465                 470                 475                 480 


Asp Ile Ala 
            


<210>  3761
<211>  420
<212>  PRT
<213>  homo sapiens

<400>  3761

Met Phe Lys Arg Thr Val Leu Ser Cys Pro Pro Pro Ala Ala Pro Pro 
1               5                   10                  15      


Leu Gln Ala Arg Gly Ala Phe Arg Ser Phe Pro His Ser Trp Gly Glu 
            20                  25                  30          


Asp Phe Leu Ala Ser Leu Met Phe Lys Ile Gln Leu Glu Pro Leu Lys 
        35                  40                  45              


Leu Arg Ala Trp Thr Leu Asn Gly Phe Val Lys Phe Arg Asn Lys Glu 
    50                  55                  60                  


Thr Ser Ala Gly Pro Val Ala Val Met Gly Lys Asp Tyr Tyr Lys Ile 
65                  70                  75                  80  


Leu Gly Ile Pro Ser Gly Ala Asn Glu Asp Glu Ile Lys Lys Ala Tyr 
                85                  90                  95      


Arg Lys Met Ala Leu Lys Tyr His Pro Asp Lys Asn Lys Glu Pro Asn 
            100                 105                 110         


Ala Glu Glu Lys Phe Lys Glu Ile Ala Glu Ala Tyr Asp Val Leu Ser 
        115                 120                 125             


Asp Pro Lys Lys Arg Gly Leu Tyr Asp Gln Tyr Gly Glu Glu Gly Leu 
    130                 135                 140                 


Lys Thr Gly Gly Gly Thr Ser Gly Gly Ser Ser Gly Ser Phe His Tyr 
145                 150                 155                 160 


Thr Phe His Gly Asp Pro His Ala Thr Phe Ala Ser Phe Phe Gly Gly 
                165                 170                 175     


Ser Asn Pro Phe Asp Ile Phe Phe Ala Ser Ser Arg Ser Thr Arg Pro 
            180                 185                 190         


Phe Ser Gly Phe Asp Pro Asp Asp Met Asp Val Asp Glu Asp Glu Asp 
        195                 200                 205             


Pro Phe Gly Ala Phe Gly Arg Phe Gly Phe Asn Gly Leu Ser Arg Gly 
    210                 215                 220                 


Pro Arg Arg Ala Pro Glu Pro Leu Tyr Pro Arg Arg Lys Val Gln Asp 
225                 230                 235                 240 


Pro Pro Val Val His Glu Leu Arg Val Ser Leu Glu Glu Ile Tyr His 
                245                 250                 255     


Gly Ser Thr Lys Arg Met Lys Ile Thr Arg Arg Arg Leu Asn Pro Asp 
            260                 265                 270         


Gly Arg Thr Val Arg Thr Glu Asp Lys Ile Leu His Ile Val Ile Lys 
        275                 280                 285             


Arg Gly Trp Lys Glu Gly Thr Lys Ile Thr Phe Pro Lys Glu Gly Asp 
    290                 295                 300                 


Ala Thr Pro Asp Asn Ile Pro Ala Asp Ile Val Phe Val Leu Lys Asp 
305                 310                 315                 320 


Lys Pro His Ala His Phe Arg Arg Asp Gly Thr Asn Val Leu Tyr Ser 
                325                 330                 335     


Ala Leu Ile Ser Leu Lys Glu Ala Leu Cys Gly Cys Thr Val Asn Ile 
            340                 345                 350         


Pro Thr Ile Asp Gly Arg Val Ile Pro Leu Pro Cys Asn Asp Val Ile 
        355                 360                 365             


Lys Pro Gly Thr Val Lys Arg Leu Arg Gly Glu Gly Leu Pro Phe Pro 
    370                 375                 380                 


Lys Val Pro Thr Gln Arg Gly Asp Leu Ile Val Glu Phe Lys Val Arg 
385                 390                 395                 400 


Phe Pro Asp Arg Leu Thr Pro Gln Thr Arg Gln Ile Leu Lys Gln His 
                405                 410                 415     


Leu Pro Cys Ser 
            420 


<210>  3762
<211>  956
<212>  PRT
<213>  homo sapiens

<400>  3762

Met Asp Leu Leu Tyr Gly Leu Val Trp Leu Leu Thr Val Leu Leu Glu 
1               5                   10                  15      


Gly Ile Ser Gly Gln Gly Val Tyr Ala Pro Pro Thr Val Arg Ile Val 
            20                  25                  30          


His Ser Gly Leu Ala Cys Asn Ile Glu Glu Glu Arg Tyr Ser Glu Arg 
        35                  40                  45              


Val Tyr Thr Ile Arg Glu Gly Glu Thr Leu Glu Leu Thr Cys Leu Val 
    50                  55                  60                  


Thr Gly His Pro Arg Pro Gln Ile Arg Trp Thr Lys Thr Ala Gly Ser 
65                  70                  75                  80  


Ala Ser Asp Arg Phe Gln Asp Ser Ser Val Phe Asn Glu Thr Leu Arg 
                85                  90                  95      


Ile Thr Asn Ile Gln Arg His Gln Gly Gly Arg Tyr Tyr Cys Lys Ala 
            100                 105                 110         


Glu Asn Gly Leu Gly Ser Pro Ala Ile Lys Ser Ile Arg Val Asp Val 
        115                 120                 125             


Tyr Tyr Leu Asp Asp Pro Val Val Thr Val His Gln Ser Ile Gly Glu 
    130                 135                 140                 


Ala Lys Glu Gln Phe Tyr Tyr Glu Arg Thr Val Phe Leu Arg Cys Val 
145                 150                 155                 160 


Ala Asn Ser Asn Pro Pro Val Arg Tyr Ser Trp Arg Arg Gly Gln Glu 
                165                 170                 175     


Val Leu Leu Gln Gly Ser Asp Lys Gly Val Glu Ile Tyr Glu Pro Phe 
            180                 185                 190         


Phe Thr Gln Gly Glu Thr Lys Ile Leu Lys Leu Lys Asn Leu Arg Pro 
        195                 200                 205             


Gln Asp Tyr Ala Asn Tyr Ser Cys Ile Ala Ser Val Arg Asn Val Cys 
    210                 215                 220                 


Asn Ile Pro Asp Lys Met Val Ser Phe Arg Leu Ser Asn Lys Thr Ala 
225                 230                 235                 240 


Ser Pro Ser Ile Lys Leu Leu Val Asp Asp Pro Ile Val Val Asn Pro 
                245                 250                 255     


Gly Glu Ala Ile Thr Leu Val Cys Val Thr Thr Gly Gly Glu Pro Ala 
            260                 265                 270         


Pro Ser Leu Thr Trp Val Arg Ser Phe Gly Thr Leu Pro Glu Lys Thr 
        275                 280                 285             


Val Leu Asn Gly Gly Thr Leu Thr Ile Pro Ala Ile Thr Ser Asp Asp 
    290                 295                 300                 


Ala Gly Thr Tyr Ser Cys Ile Ala Asn Asn Asn Val Gly Asn Pro Ala 
305                 310                 315                 320 


Lys Lys Ser Thr Asn Ile Ile Val Arg Ala Leu Lys Lys Gly Arg Phe 
                325                 330                 335     


Trp Ile Thr Pro Asp Pro Tyr His Lys Asp Asp Asn Ile Gln Ile Gly 
            340                 345                 350         


Arg Glu Val Lys Ile Ser Cys Gln Val Glu Ala Val Pro Ser Glu Glu 
        355                 360                 365             


Leu Thr Phe Ser Trp Phe Lys Asn Gly Arg Pro Leu Arg Ser Ser Glu 
    370                 375                 380                 


Arg Met Val Ile Thr Gln Thr Asp Pro Asp Val Ser Pro Gly Thr Thr 
385                 390                 395                 400 


Asn Leu Asp Ile Ile Asp Leu Lys Phe Thr Asp Phe Gly Thr Tyr Thr 
                405                 410                 415     


Cys Val Ala Ser Leu Lys Gly Gly Gly Ile Ser Asp Ile Ser Ile Asp 
            420                 425                 430         


Val Asn Ile Ser Ser Ser Thr Val Pro Pro Asn Leu Thr Val Pro Gln 
        435                 440                 445             


Glu Lys Ser Pro Leu Val Thr Arg Glu Gly Asp Thr Ile Glu Leu Gln 
    450                 455                 460                 


Cys Gln Val Thr Gly Lys Pro Lys Pro Ile Ile Leu Trp Ser Arg Ala 
465                 470                 475                 480 


Asp Lys Glu Val Ala Met Pro Asp Gly Ser Met Gln Met Glu Ser Tyr 
                485                 490                 495     


Asp Gly Thr Leu Arg Ile Val Asn Val Ser Arg Glu Met Ser Gly Met 
            500                 505                 510         


Tyr Arg Cys Gln Thr Ser Gln Tyr Asn Gly Phe Asn Val Lys Pro Arg 
        515                 520                 525             


Glu Ala Leu Val Gln Leu Ile Val Gln Tyr Pro Pro Ala Val Glu Pro 
    530                 535                 540                 


Ala Phe Leu Glu Ile Arg Gln Gly Gln Asp Arg Ser Val Thr Met Ser 
545                 550                 555                 560 


Cys Arg Val Leu Arg Ala Tyr Pro Ile Arg Val Leu Thr Tyr Glu Trp 
                565                 570                 575     


Arg Leu Gly Asn Lys Leu Leu Arg Thr Gly Gln Phe Asp Ser Gln Glu 
            580                 585                 590         


Tyr Thr Glu Tyr Ala Val Lys Ser Leu Ser Asn Glu Asn Tyr Gly Val 
        595                 600                 605             


Tyr Asn Cys Ser Ile Ile Asn Glu Ala Gly Ala Gly Arg Cys Ser Phe 
    610                 615                 620                 


Leu Val Thr Gly Lys Ala Tyr Ala Pro Glu Phe Tyr Tyr Asp Thr Tyr 
625                 630                 635                 640 


Asn Pro Val Trp Gln Asn Arg His Arg Val Tyr Ser Tyr Ser Leu Gln 
                645                 650                 655     


Trp Thr Gln Met Asn Pro Asp Ala Val Asp Arg Ile Val Ala Tyr Arg 
            660                 665                 670         


Leu Gly Ile Arg Gln Ala Gly Gln Gln Arg Trp Trp Glu Gln Glu Ile 
        675                 680                 685             


Lys Ile Asn Gly Asn Ile Gln Lys Gly Glu Leu Ile Thr Tyr Asn Leu 
    690                 695                 700                 


Thr Glu Leu Ile Lys Pro Glu Ala Tyr Glu Val Arg Leu Thr Pro Leu 
705                 710                 715                 720 


Thr Lys Phe Gly Glu Gly Asp Ser Thr Ile Arg Val Ile Lys Tyr Ser 
                725                 730                 735     


Ala Pro Val Asn Pro His Leu Arg Glu Phe His Cys Gly Phe Glu Asp 
            740                 745                 750         


Gly Asn Ile Cys Leu Phe Thr Gln Asp Asp Thr Asp Asn Phe Asp Trp 
        755                 760                 765             


Thr Lys Gln Ser Thr Ala Thr Arg Asn Thr Lys Tyr Thr Pro Asn Thr 
    770                 775                 780                 


Gly Pro Asn Ala Asp Arg Ser Gly Ser Lys Glu Gly Phe Tyr Met Tyr 
785                 790                 795                 800 


Ile Glu Thr Ser Arg Pro Arg Leu Glu Gly Glu Lys Ala Arg Leu Leu 
                805                 810                 815     


Ser Pro Val Phe Ser Ile Ala Pro Lys Asn Pro Tyr Gly Pro Thr Asn 
            820                 825                 830         


Thr Ala Tyr Cys Phe Ser Phe Phe Tyr His Met Tyr Gly Gln His Ile 
        835                 840                 845             


Gly Val Leu Asn Val Tyr Leu Arg Leu Lys Gly Gln Thr Thr Ile Glu 
    850                 855                 860                 


Asn Pro Leu Trp Ser Ser Ser Gly Asn Lys Gly Gln Arg Trp Asn Glu 
865                 870                 875                 880 


Ala His Val Asn Ile Tyr Pro Ile Thr Ser Phe Gln Leu Ile Phe Glu 
                885                 890                 895     


Gly Ile Arg Gly Pro Gly Ile Glu Gly Asp Ile Ala Ile Asp Asp Val 
            900                 905                 910         


Ser Ile Ala Glu Gly Glu Cys Ala Lys Gln Asp Leu Ala Thr Lys Asn 
        915                 920                 925             


Ser Val Asp Gly Ala Val Gly Ile Leu Val His Ile Trp Leu Phe Pro 
    930                 935                 940                 


Ile Ile Val Leu Ile Ser Ile Leu Ser Pro Arg Arg 
945                 950                 955     


<210>  3763
<211>  354
<212>  PRT
<213>  homo sapiens

<400>  3763

Met Gly Glu Gln Pro Ile Phe Ser Thr Arg Ala His Val Phe Gln Ile 
1               5                   10                  15      


Asp Pro Asn Thr Lys Lys Asn Trp Val Pro Thr Ser Lys His Ala Val 
            20                  25                  30          


Thr Val Ser Tyr Phe Tyr Asp Ser Thr Arg Asn Val Tyr Arg Ile Ile 
        35                  40                  45              


Ser Leu Asp Gly Ser Lys Ala Ile Ile Asn Ser Thr Ile Thr Pro Asn 
    50                  55                  60                  


Met Thr Phe Thr Lys Thr Ser Gln Lys Phe Gly Gln Trp Ala Asp Ser 
65                  70                  75                  80  


Arg Ala Asn Thr Val Tyr Gly Leu Gly Phe Ser Ser Glu His His Leu 
                85                  90                  95      


Ser Lys Phe Ala Glu Lys Phe Gln Glu Phe Lys Glu Ala Ala Arg Leu 
            100                 105                 110         


Ala Lys Glu Lys Ser Gln Glu Lys Met Glu Leu Thr Ser Thr Pro Ser 
        115                 120                 125             


Gln Glu Ser Ala Gly Gly Asp Leu Gln Ser Pro Leu Thr Pro Glu Ser 
    130                 135                 140                 


Ile Asn Gly Thr Asp Asp Glu Arg Thr Pro Asp Val Thr Gln Asn Ser 
145                 150                 155                 160 


Glu Pro Arg Ala Glu Pro Thr Gln Asn Ala Leu Pro Phe Ser His Ser 
                165                 170                 175     


Ser Ala Ile Ser Lys His Trp Glu Ala Glu Leu Ala Thr Leu Lys Gly 
            180                 185                 190         


Asn Asn Ala Lys Leu Thr Ala Ala Leu Leu Glu Ser Thr Ala Asn Val 
        195                 200                 205             


Lys Gln Trp Lys Gln Gln Leu Ala Ala Tyr Gln Glu Glu Ala Glu Arg 
    210                 215                 220                 


Leu His Lys Arg Val Thr Glu Leu Glu Cys Val Ser Ser Gln Ala Asn 
225                 230                 235                 240 


Ala Val His Thr His Lys Thr Glu Leu Asn Gln Thr Ile Gln Glu Leu 
                245                 250                 255     


Glu Glu Thr Leu Lys Leu Lys Glu Glu Glu Ile Glu Arg Leu Lys Gln 
            260                 265                 270         


Glu Ile Asp Asn Ala Arg Glu Leu Gln Glu Gln Arg Asp Ser Leu Thr 
        275                 280                 285             


Gln Lys Leu Gln Glu Val Glu Ile Arg Asn Lys Asp Leu Glu Gly Gln 
    290                 295                 300                 


Leu Ser Asp Leu Glu Gln Arg Leu Glu Lys Ser Gln Asn Glu Gln Glu 
305                 310                 315                 320 


Ala Phe Arg Asn Asn Leu Lys Thr Leu Leu Glu Ile Leu Asp Gly Lys 
                325                 330                 335     


Ile Phe Glu Leu Thr Glu Leu Arg Asp Asn Leu Ala Lys Leu Leu Glu 
            340                 345                 350         


Cys Ser 
        


<210>  3764
<211>  381
<212>  PRT
<213>  homo sapiens

<400>  3764

Met Leu Leu Ser Ile Gly Met Leu Met Leu Ser Ala Thr Gln Val Tyr 
1               5                   10                  15      


Thr Ile Leu Thr Val Gln Leu Phe Ala Phe Leu Asn Leu Leu Pro Val 
            20                  25                  30          


Glu Ala Asp Ile Leu Ala Tyr Asn Phe Glu Asn Ala Ser Gln Thr Phe 
        35                  40                  45              


Asp Asp Leu Pro Ala Arg Phe Gly Tyr Arg Leu Pro Ala Glu Gly Leu 
    50                  55                  60                  


Lys Gly Phe Leu Ile Asn Ser Lys Pro Glu Asn Ala Cys Glu Pro Ile 
65                  70                  75                  80  


Val Pro Pro Pro Val Lys Asp Asn Ser Ser Gly Thr Phe Ile Val Leu 
                85                  90                  95      


Ile Arg Arg Leu Asp Cys Asn Phe Asp Ile Lys Val Leu Asn Ala Gln 
            100                 105                 110         


Arg Ala Gly Tyr Lys Ala Ala Ile Val His Asn Val Asp Ser Asp Asp 
        115                 120                 125             


Leu Ile Ser Met Gly Ser Asn Asp Ile Glu Val Leu Lys Lys Ile Asp 
    130                 135                 140                 


Ile Pro Ser Val Phe Ile Gly Glu Ser Ser Ala Asn Ser Leu Lys Asp 
145                 150                 155                 160 


Glu Phe Thr Tyr Glu Lys Gly Gly His Leu Ile Leu Val Pro Glu Phe 
                165                 170                 175     


Ser Leu Pro Leu Glu Tyr Tyr Leu Ile Pro Phe Leu Ile Ile Val Gly 
            180                 185                 190         


Ile Cys Leu Ile Leu Ile Val Ile Phe Met Ile Thr Lys Phe Val Gln 
        195                 200                 205             


Asp Arg His Arg Ala Arg Arg Asn Arg Leu Arg Lys Asp Gln Leu Lys 
    210                 215                 220                 


Lys Leu Pro Val His Lys Phe Lys Lys Gly Asp Glu Tyr Asp Val Cys 
225                 230                 235                 240 


Ala Ile Cys Leu Asp Glu Tyr Glu Asp Gly Asp Lys Leu Arg Ile Leu 
                245                 250                 255     


Pro Cys Ser His Ala Tyr His Cys Lys Cys Val Asp Pro Trp Leu Thr 
            260                 265                 270         


Lys Thr Lys Lys Thr Cys Pro Val Cys Lys Gln Lys Val Val Pro Ser 
        275                 280                 285             


Gln Gly Asp Ser Asp Ser Asp Thr Asp Ser Ser Gln Glu Glu Asn Glu 
    290                 295                 300                 


Val Thr Glu His Thr Pro Leu Leu Arg Pro Leu Ala Ser Val Ser Ala 
305                 310                 315                 320 


Gln Ser Phe Gly Ala Leu Ser Glu Ser Arg Ser His Gln Asn Met Thr 
                325                 330                 335     


Glu Ser Ser Asp Tyr Glu Glu Asp Asp Asn Glu Asp Thr Asp Ser Ser 
            340                 345                 350         


Asp Ala Glu Asn Glu Ile Asn Glu His Asp Val Val Val Gln Leu Gln 
        355                 360                 365             


Pro Asn Gly Glu Arg Asp Tyr Asn Ile Ala Asn Thr Val 
    370                 375                 380     


<210>  3765
<211>  381
<212>  PRT
<213>  homo sapiens

<400>  3765

Met Leu Leu Ser Ile Gly Met Leu Met Leu Ser Ala Thr Gln Val Tyr 
1               5                   10                  15      


Thr Ile Leu Thr Val Gln Leu Phe Ala Phe Leu Asn Leu Leu Pro Val 
            20                  25                  30          


Glu Ala Asp Ile Leu Ala Tyr Asn Phe Glu Asn Ala Ser Gln Thr Phe 
        35                  40                  45              


Asp Asp Leu Pro Ala Arg Phe Gly Tyr Arg Leu Pro Ala Glu Gly Leu 
    50                  55                  60                  


Lys Gly Phe Leu Ile Asn Ser Lys Pro Glu Asn Ala Cys Glu Pro Ile 
65                  70                  75                  80  


Val Pro Pro Pro Val Lys Asp Asn Ser Ser Gly Thr Phe Ile Val Leu 
                85                  90                  95      


Ile Arg Arg Leu Asp Cys Asn Phe Asp Ile Lys Val Leu Asn Ala Gln 
            100                 105                 110         


Arg Ala Gly Tyr Lys Ala Ala Ile Val His Asn Val Asp Ser Asp Asp 
        115                 120                 125             


Leu Ile Ser Met Gly Ser Asn Asp Ile Glu Val Leu Lys Lys Ile Asp 
    130                 135                 140                 


Ile Pro Ser Val Phe Ile Gly Glu Ser Ser Ala Asn Ser Leu Lys Asp 
145                 150                 155                 160 


Glu Phe Thr Tyr Glu Lys Gly Gly His Leu Ile Leu Val Pro Glu Phe 
                165                 170                 175     


Ser Leu Pro Leu Glu Tyr Tyr Leu Ile Pro Phe Leu Ile Ile Val Gly 
            180                 185                 190         


Ile Cys Leu Ile Leu Ile Val Ile Phe Met Ile Thr Lys Phe Val Gln 
        195                 200                 205             


Asp Arg His Arg Ala Arg Arg Asn Arg Leu Arg Lys Asp Gln Leu Lys 
    210                 215                 220                 


Lys Leu Pro Val His Lys Phe Lys Lys Gly Asp Glu Tyr Asp Val Cys 
225                 230                 235                 240 


Ala Ile Cys Leu Asp Glu Tyr Glu Asp Gly Asp Lys Leu Arg Ile Leu 
                245                 250                 255     


Pro Cys Ser His Ala Tyr His Cys Lys Cys Val Asp Pro Trp Leu Thr 
            260                 265                 270         


Lys Thr Lys Lys Thr Cys Pro Val Cys Lys Gln Lys Val Val Pro Ser 
        275                 280                 285             


Gln Gly Asp Ser Asp Ser Asp Thr Asp Ser Ser Gln Glu Glu Asn Glu 
    290                 295                 300                 


Val Thr Glu His Thr Pro Leu Leu Arg Pro Leu Ala Ser Val Ser Ala 
305                 310                 315                 320 


Gln Ser Phe Gly Ala Leu Ser Glu Ser Arg Ser His Gln Asn Met Thr 
                325                 330                 335     


Glu Ser Ser Asp Tyr Glu Glu Asp Asp Asn Glu Asp Thr Asp Ser Ser 
            340                 345                 350         


Asp Ala Glu Asn Glu Ile Asn Glu His Asp Val Val Val Gln Leu Gln 
        355                 360                 365             


Pro Asn Gly Glu Arg Asp Tyr Asn Ile Ala Asn Thr Val 
    370                 375                 380     


<210>  3766
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  3766

Met Ala Ser Gln Pro Pro Glu Asp Thr Ala Glu Ser Gln Ala Ser Asp 
1               5                   10                  15      


Glu Leu Glu Cys Lys Ile Cys Tyr Asn Arg Tyr Asn Leu Lys Gln Arg 
            20                  25                  30          


Lys Pro Lys Val Leu Glu Cys Cys His Arg Val Cys Ala Lys Cys Leu 
        35                  40                  45              


Tyr Lys Ile Ile Asp Phe Gly Asp Ser Pro Gln Gly Val Ile Val Cys 
    50                  55                  60                  


Pro Phe Cys Arg Phe Glu Thr Cys Leu Pro Asp Asp Glu Val Ser Ser 
65                  70                  75                  80  


Leu Pro Asp Asp Asn Asn Ile Leu Val Asn Leu Thr Cys Gly Gly Lys 
                85                  90                  95      


Gly Lys Lys Cys Leu Pro Glu Asn Pro Thr Glu Leu Leu Leu Thr Pro 
            100                 105                 110         


Lys Arg Leu Ala Ser Leu Val Ser Pro Ser His Thr Ser Ser Asn Cys 
        115                 120                 125             


Leu Val Ile Thr Ile Met Glu Val Gln Arg Glu Ser Ser Pro Ser Leu 
    130                 135                 140                 


Ser Ser Thr Pro Val Val Glu Phe Tyr Arg Pro Ala Ser Phe Asp Ser 
145                 150                 155                 160 


Val Thr Thr Val Ser His Asn Trp Thr Val Trp Asn Cys Thr Ser Leu 
                165                 170                 175     


Leu Phe Gln Thr Ser Ile Arg Val Leu Val Trp Leu Leu Gly Leu Leu 
            180                 185                 190         


Tyr Phe Ser Ser Leu Pro Leu Gly Ile Tyr Leu Leu Val Ser Lys Lys 
        195                 200                 205             


Val Thr Leu Gly Val Val Phe Val Ser Leu Val Pro Ser Ser Leu Val 
    210                 215                 220                 


Ile Leu Met Val Tyr Gly Phe Cys Gln Cys Val Cys His Glu Phe Leu 
225                 230                 235                 240 


Asp Cys Met Ala Pro Pro Ser 
                245         


<210>  3767
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  3767

Met Ala Ser Gln Pro Pro Glu Asp Thr Ala Glu Ser Gln Ala Ser Asp 
1               5                   10                  15      


Glu Leu Glu Cys Lys Ile Cys Tyr Asn Arg Tyr Asn Leu Lys Gln Arg 
            20                  25                  30          


Lys Pro Lys Val Leu Glu Cys Cys His Arg Val Cys Ala Lys Cys Leu 
        35                  40                  45              


Tyr Lys Ile Ile Asp Phe Gly Asp Ser Pro Gln Gly Val Ile Val Cys 
    50                  55                  60                  


Pro Phe Cys Arg Phe Glu Thr Cys Leu Pro Asp Asp Glu Val Ser Ser 
65                  70                  75                  80  


Leu Pro Asp Asp Asn Asn Ile Leu Val Asn Leu Thr Cys Gly Gly Lys 
                85                  90                  95      


Gly Lys Lys Cys Leu Pro Glu Asn Pro Thr Glu Leu Leu Leu Thr Pro 
            100                 105                 110         


Lys Arg Leu Ala Ser Leu Val Ser Pro Ser His Thr Ser Ser Asn Cys 
        115                 120                 125             


Leu Val Ile Thr Ile Met Glu Val Gln Arg Glu Ser Ser Pro Ser Leu 
    130                 135                 140                 


Ser Ser Thr Pro Val Val Glu Phe Tyr Arg Pro Ala Ser Phe Asp Ser 
145                 150                 155                 160 


Val Thr Thr Val Ser His Asn Trp Thr Val Trp Asn Cys Thr Ser Leu 
                165                 170                 175     


Leu Phe Gln Thr Ser Ile Arg Val Leu Val Trp Leu Leu Gly Leu Leu 
            180                 185                 190         


Tyr Phe Ser Ser Leu Pro Leu Gly Ile Tyr Leu Leu Val Ser Lys Lys 
        195                 200                 205             


Val Thr Leu Gly Val Val Phe Val Ser Leu Val Pro Ser Ser Leu Val 
    210                 215                 220                 


Ile Leu Met Val Tyr Gly Phe Cys Gln Cys Val Cys His Glu Phe Leu 
225                 230                 235                 240 


Asp Cys Met Ala Pro Pro Ser 
                245         


<210>  3768
<211>  354
<212>  PRT
<213>  homo sapiens

<400>  3768

Met Ser Ala Gly Gly Gly Arg Ala Phe Ala Trp Gln Val Phe Pro Pro 
1               5                   10                  15      


Met Pro Thr Cys Arg Val Tyr Gly Thr Val Ala His Gln Asp Gly His 
            20                  25                  30          


Leu Leu Val Leu Gly Gly Cys Gly Arg Ala Gly Leu Pro Leu Asp Thr 
        35                  40                  45              


Ala Glu Thr Leu Asp Met Ala Ser His Thr Trp Leu Ala Leu Ala Pro 
    50                  55                  60                  


Leu Pro Thr Ala Arg Ala Gly Ala Ala Ala Val Val Leu Gly Lys Gln 
65                  70                  75                  80  


Val Leu Val Val Gly Gly Val Asp Glu Val Gln Ser Pro Val Ala Ala 
                85                  90                  95      


Val Glu Ala Phe Leu Met Asp Glu Gly Arg Trp Glu Arg Arg Ala Thr 
            100                 105                 110         


Leu Pro Gln Ala Ala Met Gly Val Ala Thr Val Glu Arg Asp Gly Met 
        115                 120                 125             


Val Tyr Ala Leu Gly Gly Met Gly Pro Asp Thr Ala Pro Gln Ala Gln 
    130                 135                 140                 


Val Arg Val Tyr Glu Pro Arg Arg Asp Cys Trp Leu Ser Leu Pro Ser 
145                 150                 155                 160 


Met Pro Thr Pro Cys Tyr Gly Ala Ser Thr Phe Leu His Gly Asn Lys 
                165                 170                 175     


Ile Tyr Val Leu Gly Gly Arg Gln Gly Lys Leu Pro Val Thr Ala Phe 
            180                 185                 190         


Glu Ala Phe Asp Leu Glu Ala Arg Thr Trp Thr Arg His Pro Ser Leu 
        195                 200                 205             


Pro Ser Arg Arg Ala Phe Ala Gly Cys Ala Met Ala Glu Gly Ser Val 
    210                 215                 220                 


Phe Ser Leu Gly Gly Leu Gln Gln Pro Gly Pro His Asn Phe Tyr Ser 
225                 230                 235                 240 


Arg Pro His Phe Val Asn Thr Val Glu Met Phe Asp Leu Glu His Gly 
                245                 250                 255     


Ser Trp Thr Lys Leu Pro Arg Ser Leu Arg Met Arg Asp Lys Arg Ala 
            260                 265                 270         


Asp Phe Val Val Gly Ser Leu Gly Gly His Ile Val Ala Ile Gly Gly 
        275                 280                 285             


Leu Gly Asn Gln Pro Cys Pro Leu Gly Ser Val Glu Ser Phe Ser Leu 
    290                 295                 300                 


Ala Arg Arg Arg Trp Glu Ala Leu Pro Ala Met Pro Thr Ala Arg Cys 
305                 310                 315                 320 


Ser Cys Ser Ser Leu Gln Ala Gly Pro Arg Leu Phe Val Ile Gly Gly 
                325                 330                 335     


Val Ala Gln Gly Pro Ser Gln Ala Val Glu Ala Leu Cys Leu Arg Asp 
            340                 345                 350         


Gly Val 
        


<210>  3769
<211>  558
<212>  PRT
<213>  homo sapiens

<400>  3769

Met Ala Leu Lys Gly Gln Glu Asp Tyr Ile Tyr Leu Phe Lys Asp Ser 
1               5                   10                  15      


Thr His Pro Val Asp Phe Leu Asp Ala Phe Arg Thr Phe Tyr Leu Asp 
            20                  25                  30          


Gly Leu Phe Thr Asp Ile Thr Leu Gln Cys Pro Ser Gly Ile Ile Phe 
        35                  40                  45              


His Cys His Arg Ala Val Leu Ala Ala Cys Ser Asn Tyr Phe Lys Ala 
    50                  55                  60                  


Met Phe Thr Ala Asp Met Lys Glu Lys Phe Lys Asn Lys Ile Lys Leu 
65                  70                  75                  80  


Ser Gly Ile His His Asp Ile Leu Glu Gly Leu Val Asn Tyr Ala Tyr 
                85                  90                  95      


Thr Ser Gln Ile Glu Ile Thr Lys Arg Asn Val Gln Ser Leu Leu Glu 
            100                 105                 110         


Ala Ala Asp Leu Leu Gln Phe Leu Ser Val Lys Lys Ala Cys Glu Arg 
        115                 120                 125             


Phe Leu Val Arg His Leu Asp Ile Asp Asn Cys Ile Gly Met His Ser 
    130                 135                 140                 


Phe Ala Glu Phe His Val Cys Pro Glu Leu Glu Lys Glu Ser Arg Arg 
145                 150                 155                 160 


Ile Leu Cys Ser Lys Phe Lys Glu Val Trp Gln Gln Glu Glu Phe Leu 
                165                 170                 175     


Glu Ile Ser Leu Glu Lys Phe Leu Phe Ile Leu Ser Arg Lys Asn Leu 
            180                 185                 190         


Ser Val Trp Lys Glu Glu Ala Ile Ile Glu Pro Val Ile Lys Trp Thr 
        195                 200                 205             


Ala His Asp Val Glu Asn Arg Ile Glu Cys Leu Tyr Asn Leu Leu Ser 
    210                 215                 220                 


Tyr Ile Asn Ile Asp Ile Asp Pro Val Tyr Leu Lys Thr Ala Leu Gly 
225                 230                 235                 240 


Leu Gln Arg Ser Cys Leu Leu Thr Glu Asn Lys Ile Arg Ser Leu Ile 
                245                 250                 255     


Tyr Asn Ala Leu Asn Pro Met His Lys Glu Ile Ser Gln Arg Ser Thr 
            260                 265                 270         


Ala Thr Met Tyr Ile Ile Gly Gly Tyr Tyr Trp His Pro Leu Ser Glu 
        275                 280                 285             


Val His Ile Trp Asp Pro Leu Thr Asn Val Trp Ile Gln Gly Ala Glu 
    290                 295                 300                 


Ile Pro Asp Tyr Thr Arg Glu Ser Tyr Gly Val Thr Cys Leu Gly Pro 
305                 310                 315                 320 


Asn Ile Tyr Val Thr Gly Gly Tyr Arg Thr Asp Asn Ile Glu Ala Leu 
                325                 330                 335     


Asp Thr Val Trp Ile Tyr Asn Ser Glu Ser Asp Glu Trp Thr Glu Gly 
            340                 345                 350         


Leu Pro Met Leu Asn Ala Arg Tyr Tyr His Cys Ala Val Thr Leu Gly 
        355                 360                 365             


Gly Cys Val Tyr Ala Leu Gly Gly Tyr Arg Lys Gly Ala Pro Ala Glu 
    370                 375                 380                 


Glu Ala Glu Phe Tyr Asp Pro Leu Lys Glu Lys Trp Ile Pro Ile Ala 
385                 390                 395                 400 


Asn Met Ile Lys Gly Val Gly Asn Ala Thr Ala Cys Val Leu His Asp 
                405                 410                 415     


Val Ile Tyr Val Ile Gly Gly His Cys Gly Tyr Arg Gly Ser Cys Thr 
            420                 425                 430         


Tyr Asp Lys Val Gln Ser Tyr Asn Ser Asp Ile Asn Glu Trp Ser Leu 
        435                 440                 445             


Ile Thr Ser Ser Pro His Pro Glu Tyr Gly Leu Cys Ser Val Pro Phe 
    450                 455                 460                 


Glu Asn Lys Leu Tyr Leu Val Gly Gly Gln Thr Thr Ile Thr Glu Cys 
465                 470                 475                 480 


Tyr Asp Pro Glu Gln Asn Glu Trp Arg Glu Ile Ala Pro Met Met Glu 
                485                 490                 495     


Arg Arg Met Glu Cys Gly Ala Val Ile Met Asn Gly Cys Ile Tyr Val 
            500                 505                 510         


Thr Gly Gly Tyr Ser Tyr Ser Lys Gly Thr Tyr Leu Gln Ser Ile Glu 
        515                 520                 525             


Lys Tyr Asp Pro Asp Leu Asn Lys Trp Glu Ile Val Gly Asn Leu Pro 
    530                 535                 540                 


Ser Ala Met Arg Ser His Gly Cys Val Cys Val Tyr Asn Val 
545                 550                 555             


<210>  3770
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  3770

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  3771
<211>  825
<212>  PRT
<213>  homo sapiens

<400>  3771

Met Pro Ser Thr Ser Phe Pro Val Pro Ser Lys Phe Pro Leu Gly Pro 
1               5                   10                  15      


Ala Ala Ala Val Phe Gly Arg Gly Glu Thr Leu Gly Pro Ala Pro Arg 
            20                  25                  30          


Ala Gly Gly Thr Met Lys Ser Ala Glu Glu Glu His Tyr Gly Tyr Ala 
        35                  40                  45              


Ser Ser Asn Val Ser Pro Ala Leu Pro Leu Pro Thr Ala His Ser Thr 
    50                  55                  60                  


Leu Pro Ala Pro Cys His Asn Leu Gln Thr Ser Thr Pro Gly Ile Ile 
65                  70                  75                  80  


Pro Pro Ala Asp His Pro Ser Gly Tyr Gly Ala Ala Leu Asp Gly Gly 
                85                  90                  95      


Pro Ala Gly Tyr Phe Leu Ser Ser Gly His Thr Arg Pro Asp Gly Ala 
            100                 105                 110         


Pro Ala Leu Glu Ser Pro Arg Ile Glu Ile Thr Ser Cys Leu Gly Leu 
        115                 120                 125             


Tyr His Asn Asn Asn Gln Phe Phe His Asp Val Glu Val Glu Asp Val 
    130                 135                 140                 


Leu Pro Ser Ser Lys Arg Ser Pro Ser Thr Ala Thr Leu Ser Leu Pro 
145                 150                 155                 160 


Ser Leu Glu Ala Tyr Arg Asp Pro Ser Cys Leu Ser Pro Ala Ser Ser 
                165                 170                 175     


Leu Ser Ser Arg Ser Cys Asn Ser Glu Ala Ser Ser Tyr Glu Ser Asn 
            180                 185                 190         


Tyr Ser Tyr Pro Tyr Ala Ser Pro Gln Thr Ser Pro Trp Gln Ser Pro 
        195                 200                 205             


Cys Val Ser Pro Lys Thr Thr Asp Pro Glu Glu Gly Phe Pro Arg Gly 
    210                 215                 220                 


Leu Gly Ala Cys Thr Leu Leu Gly Ser Pro Arg His Ser Pro Ser Thr 
225                 230                 235                 240 


Ser Pro Arg Ala Ser Val Thr Glu Glu Ser Trp Leu Gly Ala Arg Ser 
                245                 250                 255     


Ser Arg Pro Ala Ser Pro Cys Asn Lys Arg Lys Tyr Ser Leu Asn Gly 
            260                 265                 270         


Arg Gln Pro Pro Tyr Ser Pro His His Ser Pro Thr Pro Ser Pro His 
        275                 280                 285             


Gly Ser Pro Arg Val Ser Val Thr Asp Asp Ser Trp Leu Gly Asn Thr 
    290                 295                 300                 


Thr Gln Tyr Thr Ser Ser Ala Ile Val Ala Ala Ile Asn Ala Leu Thr 
305                 310                 315                 320 


Thr Asp Ser Ser Leu Asp Leu Gly Asp Gly Val Pro Val Lys Ser Arg 
                325                 330                 335     


Lys Thr Thr Leu Glu Gln Pro Pro Ser Val Ala Leu Lys Val Glu Pro 
            340                 345                 350         


Val Gly Glu Asp Leu Gly Ser Pro Pro Pro Pro Ala Asp Phe Ala Pro 
        355                 360                 365             


Glu Asp Tyr Ser Ser Phe Gln His Ile Arg Lys Gly Gly Phe Cys Asp 
    370                 375                 380                 


Gln Tyr Leu Ala Val Pro Gln His Pro Tyr Gln Trp Ala Lys Pro Lys 
385                 390                 395                 400 


Pro Leu Ser Pro Thr Ser Tyr Met Ser Pro Thr Leu Pro Ala Leu Asp 
                405                 410                 415     


Trp Gln Leu Pro Ser His Ser Gly Pro Tyr Glu Leu Arg Ile Glu Val 
            420                 425                 430         


Gln Pro Lys Ser His His Arg Ala His Tyr Glu Thr Glu Gly Ser Arg 
        435                 440                 445             


Gly Ala Val Lys Ala Ser Ala Gly Gly His Pro Ile Val Gln Leu His 
    450                 455                 460                 


Gly Tyr Leu Glu Asn Glu Pro Leu Met Leu Gln Leu Phe Ile Gly Thr 
465                 470                 475                 480 


Ala Asp Asp Arg Leu Leu Arg Pro His Ala Phe Tyr Gln Val His Arg 
                485                 490                 495     


Ile Thr Gly Lys Thr Val Ser Thr Thr Ser His Glu Ala Ile Leu Ser 
            500                 505                 510         


Asn Thr Lys Val Leu Glu Ile Pro Leu Leu Pro Glu Asn Ser Met Arg 
        515                 520                 525             


Ala Val Ile Asp Cys Ala Gly Ile Leu Lys Leu Arg Asn Ser Asp Ile 
    530                 535                 540                 


Glu Leu Arg Lys Gly Glu Thr Asp Ile Gly Arg Lys Asn Thr Arg Val 
545                 550                 555                 560 


Arg Leu Val Phe Arg Val His Val Pro Gln Pro Ser Gly Arg Thr Leu 
                565                 570                 575     


Ser Leu Gln Val Ala Ser Asn Pro Ile Glu Cys Ser Gln Arg Ser Ala 
            580                 585                 590         


Gln Glu Leu Pro Leu Val Glu Lys Gln Ser Thr Asp Ser Tyr Pro Val 
        595                 600                 605             


Val Gly Gly Lys Lys Met Val Leu Ser Gly His Asn Phe Leu Gln Asp 
    610                 615                 620                 


Ser Lys Val Ile Phe Val Glu Lys Ala Pro Asp Gly His His Val Trp 
625                 630                 635                 640 


Glu Met Glu Ala Lys Thr Asp Arg Asp Leu Cys Lys Pro Asn Ser Leu 
                645                 650                 655     


Val Val Glu Ile Pro Pro Phe Arg Asn Gln Arg Ile Thr Ser Pro Val 
            660                 665                 670         


His Val Ser Phe Tyr Val Cys Asn Gly Lys Arg Lys Arg Ser Gln Tyr 
        675                 680                 685             


Gln Arg Phe Thr Tyr Leu Pro Ala Asn Val Pro Ile Ile Lys Thr Glu 
    690                 695                 700                 


Pro Thr Asp Asp Tyr Glu Pro Ala Pro Thr Cys Gly Pro Val Ser Gln 
705                 710                 715                 720 


Gly Leu Ser Pro Leu Pro Arg Pro Tyr Tyr Ser Gln Gln Leu Ala Met 
                725                 730                 735     


Pro Pro Asp Pro Ser Ser Cys Leu Val Ala Gly Phe Pro Pro Cys Pro 
            740                 745                 750         


Gln Arg Ser Thr Leu Met Pro Ala Ala Pro Gly Val Ser Pro Lys Leu 
        755                 760                 765             


His Asp Leu Ser Pro Ala Ala Tyr Thr Lys Gly Val Ala Ser Pro Gly 
    770                 775                 780                 


His Cys His Leu Gly Leu Pro Gln Pro Ala Gly Glu Ala Pro Ala Val 
785                 790                 795                 800 


Gln Asp Val Pro Arg Pro Val Ala Thr His Pro Gly Ser Pro Gly Gln 
                805                 810                 815     


Pro Pro Pro Ala Leu Leu Pro Gln Gln 
            820                 825 


<210>  3772
<211>  772
<212>  PRT
<213>  homo sapiens

<400>  3772

Met Leu Ser Leu Lys Lys Tyr Leu Thr Glu Gly Leu Leu Gln Phe Thr 
1               5                   10                  15      


Ile Leu Leu Ser Leu Ile Gly Val Arg Val Asp Val Asp Thr Tyr Leu 
            20                  25                  30          


Thr Ser Gln Leu Pro Pro Leu Arg Glu Ile Ile Leu Gly Pro Ser Ser 
        35                  40                  45              


Ala Tyr Thr Gln Thr Gln Phe His Asn Leu Arg Asn Thr Leu Asp Gly 
    50                  55                  60                  


Tyr Gly Ile His Pro Lys Ser Ile Asp Leu Asp Asn Tyr Phe Thr Ala 
65                  70                  75                  80  


Arg Arg Leu Leu Ser Gln Val Arg Ala Leu Asp Arg Phe Gln Val Pro 
                85                  90                  95      


Thr Thr Glu Val Asn Ala Trp Leu Val His Arg Asp Pro Glu Gly Ser 
            100                 105                 110         


Val Ser Gly Ser Gln Pro Asn Ser Gly Leu Ala Leu Glu Ser Ser Ser 
        115                 120                 125             


Gly Leu Gln Asp Val Thr Gly Pro Asp Asn Gly Val Arg Glu Ser Glu 
    130                 135                 140                 


Thr Glu Gln Gly Phe Gly Glu Asp Leu Glu Asp Leu Gly Ala Val Ala 
145                 150                 155                 160 


Pro Pro Val Ser Gly Asp Leu Thr Lys Glu Asp Ile Asp Leu Ile Asp 
                165                 170                 175     


Ile Leu Trp Arg Gln Asp Ile Asp Leu Gly Ala Gly Arg Glu Val Phe 
            180                 185                 190         


Asp Tyr Ser His Arg Gln Lys Glu Gln Asp Val Glu Lys Glu Leu Arg 
        195                 200                 205             


Asp Gly Gly Glu Gln Asp Thr Trp Ala Gly Glu Gly Ala Glu Ala Leu 
    210                 215                 220                 


Ala Arg Asn Leu Leu Val Asp Gly Glu Thr Gly Glu Ser Phe Pro Ala 
225                 230                 235                 240 


Gln Val Pro Ser Gly Glu Asp Gln Thr Ala Leu Ser Leu Glu Glu Cys 
                245                 250                 255     


Leu Arg Leu Leu Glu Ala Thr Cys Pro Phe Gly Glu Asn Ala Glu Phe 
            260                 265                 270         


Pro Ala Asp Ile Ser Ser Ile Thr Glu Ala Val Pro Ser Glu Ser Glu 
        275                 280                 285             


Pro Pro Ala Leu Gln Asn Asn Leu Leu Ser Pro Leu Leu Thr Gly Thr 
    290                 295                 300                 


Glu Ser Pro Phe Asp Leu Glu Gln Gln Trp Gln Asp Leu Met Ser Ile 
305                 310                 315                 320 


Met Glu Met Gln Ala Met Glu Val Asn Thr Ser Ala Ser Glu Ile Leu 
                325                 330                 335     


Tyr Ser Ala Pro Pro Gly Asp Pro Leu Ser Thr Asn Tyr Ser Leu Ala 
            340                 345                 350         


Pro Asn Thr Pro Ile Asn Gln Asn Val Ser Leu His Gln Ala Ser Leu 
        355                 360                 365             


Gly Gly Cys Ser Gln Asp Phe Leu Leu Phe Ser Pro Glu Val Glu Ser 
    370                 375                 380                 


Leu Pro Val Ala Ser Ser Ser Thr Leu Leu Pro Leu Ala Pro Ser Asn 
385                 390                 395                 400 


Ser Thr Ser Leu Asn Ser Thr Phe Gly Ser Thr Asn Leu Thr Gly Leu 
                405                 410                 415     


Phe Phe Pro Pro Gln Leu Asn Gly Thr Ala Asn Asp Thr Ala Gly Pro 
            420                 425                 430         


Glu Leu Pro Asp Pro Leu Gly Gly Leu Leu Asp Glu Ala Met Leu Asp 
        435                 440                 445             


Glu Ile Ser Leu Met Asp Leu Ala Ile Glu Glu Gly Phe Asn Pro Val 
    450                 455                 460                 


Gln Ala Ser Gln Leu Glu Glu Glu Phe Asp Ser Asp Ser Gly Leu Ser 
465                 470                 475                 480 


Leu Asp Ser Ser His Ser Pro Ser Ser Leu Ser Ser Ser Glu Gly Ser 
                485                 490                 495     


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ala Ser Ser 
            500                 505                 510         


Ser Ala Ser Ser Ser Phe Ser Glu Glu Gly Ala Val Gly Tyr Ser Ser 
        515                 520                 525             


Asp Ser Glu Thr Leu Asp Leu Glu Glu Ala Glu Gly Ala Val Gly Tyr 
    530                 535                 540                 


Gln Pro Glu Tyr Ser Lys Phe Cys Arg Met Ser Tyr Gln Asp Pro Ala 
545                 550                 555                 560 


Gln Leu Ser Cys Leu Pro Tyr Leu Glu His Val Gly His Asn His Thr 
                565                 570                 575     


Tyr Asn Met Ala Pro Ser Ala Leu Asp Ser Ala Asp Leu Pro Pro Pro 
            580                 585                 590         


Ser Ala Leu Lys Lys Gly Ser Lys Glu Lys Gln Ala Asp Phe Leu Asp 
        595                 600                 605             


Lys Gln Met Ser Arg Asp Glu His Arg Ala Arg Ala Met Lys Ile Pro 
    610                 615                 620                 


Phe Thr Asn Asp Lys Ile Ile Asn Leu Pro Val Glu Glu Phe Asn Glu 
625                 630                 635                 640 


Leu Leu Ser Lys Tyr Gln Leu Ser Glu Ala Gln Leu Ser Leu Ile Arg 
                645                 650                 655     


Asp Ile Arg Arg Arg Gly Lys Asn Lys Met Ala Ala Gln Asn Cys Arg 
            660                 665                 670         


Lys Arg Lys Leu Asp Thr Ile Leu Asn Leu Glu Arg Asp Val Glu Asp 
        675                 680                 685             


Leu Gln Arg Asp Lys Ala Arg Leu Leu Arg Glu Lys Val Glu Phe Leu 
    690                 695                 700                 


Arg Ser Leu Arg Gln Met Lys Gln Lys Val Gln Ser Leu Tyr Gln Glu 
705                 710                 715                 720 


Val Phe Gly Arg Leu Arg Asp Glu Asn Gly Arg Pro Tyr Ser Pro Ser 
                725                 730                 735     


Gln Tyr Ala Leu Gln Tyr Ala Gly Asp Gly Ser Val Leu Leu Ile Pro 
            740                 745                 750         


Arg Thr Met Ala Asp Gln Gln Ala Arg Arg Gln Glu Arg Lys Pro Lys 
        755                 760                 765             


Asp Arg Arg Lys 
    770         


<210>  3773
<211>  135
<212>  PRT
<213>  homo sapiens

<400>  3773

Met Pro Gly Arg Trp Arg Trp Gln Arg Asp Met His Pro Ala Arg Lys 
1               5                   10                  15      


Leu Leu Ser Leu Leu Phe Leu Ile Leu Met Gly Thr Glu Leu Thr Gln 
            20                  25                  30          


Val Leu Pro Thr Asn Pro Glu Glu Ser Trp Gln Val Tyr Ser Ser Ala 
        35                  40                  45              


Gln Asp Ser Glu Gly Arg Cys Ile Cys Thr Val Val Ala Pro Gln Gln 
    50                  55                  60                  


Thr Met Cys Ser Arg Asp Ala Arg Thr Lys Gln Leu Arg Gln Leu Leu 
65                  70                  75                  80  


Glu Lys Val Gln Asn Met Ser Gln Ser Ile Glu Val Leu Asp Arg Arg 
                85                  90                  95      


Thr Gln Arg Asp Leu Gln Tyr Val Glu Lys Met Glu Asn Gln Met Lys 
            100                 105                 110         


Gly Leu Glu Ser Lys Phe Lys Gln Val Glu Glu Ser His Lys Gln His 
        115                 120                 125             


Leu Ala Arg Gln Phe Lys Gly 
    130                 135 


<210>  3774
<211>  95
<212>  PRT
<213>  homo sapiens

<400>  3774

Met Glu Leu Val Leu Val Phe Leu Cys Ser Leu Leu Ala Pro Met Val 
1               5                   10                  15      


Leu Ala Ser Ala Ala Glu Lys Glu Lys Glu Met Asp Pro Phe His Tyr 
            20                  25                  30          


Asp Tyr Gln Thr Leu Arg Ile Gly Gly Leu Val Phe Ala Val Val Leu 
        35                  40                  45              


Phe Ser Val Gly Ile Leu Leu Ile Leu Ser Arg Arg Cys Lys Cys Ser 
    50                  55                  60                  


Phe Asn Gln Lys Pro Arg Ala Pro Gly Asp Glu Glu Ala Gln Val Glu 
65                  70                  75                  80  


Asn Leu Ile Thr Ala Asn Ala Thr Glu Pro Gln Lys Ala Glu Asn 
                85                  90                  95  


<210>  3775
<211>  236
<212>  PRT
<213>  homo sapiens

<400>  3775

Met Phe Cys Thr Leu Asn Thr His Lys Val Asp Met Asp Lys Leu Leu 
1               5                   10                  15      


Gly Gly Gln Ile Gly Leu Glu Asp Phe Ile Phe Ala His Val Lys Gly 
            20                  25                  30          


Gln Arg Lys Glu Val Glu Val Phe Lys Ser Glu Asp Ala Leu Gly Leu 
        35                  40                  45              


Thr Ile Thr Asp Asn Gly Ala Gly Tyr Ala Phe Ile Lys Arg Ile Lys 
    50                  55                  60                  


Glu Gly Ser Val Ile Asp His Ile His Leu Ile Ser Val Gly Asp Met 
65                  70                  75                  80  


Ile Glu Ala Ile Asn Gly Gln Ser Leu Leu Gly Cys Arg His Tyr Glu 
                85                  90                  95      


Val Ala Arg Leu Leu Lys Glu Leu Pro Arg Gly Arg Thr Phe Thr Leu 
            100                 105                 110         


Lys Leu Thr Glu Pro Arg Lys Ala Phe Asp Met Ile Ser Gln Arg Ser 
        115                 120                 125             


Ala Gly Gly Arg Pro Gly Ser Gly Pro Gln Leu Gly Thr Gly Arg Gly 
    130                 135                 140                 


Thr Leu Arg Leu Arg Ser Arg Gly Pro Ala Thr Val Glu Asp Leu Pro 
145                 150                 155                 160 


Ser Ala Phe Glu Glu Lys Ala Ile Glu Lys Val Asp Asp Leu Leu Glu 
                165                 170                 175     


Ser Tyr Met Gly Ile Arg Asp Thr Glu Leu Ala Ala Thr Met Val Glu 
            180                 185                 190         


Leu Gly Lys Asp Lys Arg Asn Pro Asp Glu Leu Ala Glu Ala Leu Asp 
        195                 200                 205             


Glu Arg Leu Gly Asp Phe Ala Phe Pro Asp Glu Phe Val Phe Asp Val 
    210                 215                 220                 


Trp Gly Ala Ile Gly Asp Ala Lys Val Gly Arg Tyr 
225                 230                 235     


<210>  3776
<211>  1064
<212>  PRT
<213>  homo sapiens

<400>  3776

Met Lys Ile Ala Thr Val Ser Val Leu Leu Pro Leu Ala Leu Cys Leu 
1               5                   10                  15      


Ile Gln Asp Ala Ala Ser Lys Asn Glu Asp Gln Glu Met Cys His Glu 
            20                  25                  30          


Phe Gln Ala Phe Met Lys Asn Gly Lys Leu Phe Cys Pro Gln Asp Lys 
        35                  40                  45              


Lys Phe Phe Gln Ser Leu Asp Gly Ile Met Phe Ile Asn Lys Cys Ala 
    50                  55                  60                  


Thr Cys Lys Met Ile Leu Glu Lys Glu Ala Lys Ser Gln Lys Arg Ala 
65                  70                  75                  80  


Arg His Leu Ala Arg Ala Pro Lys Ala Thr Ala Pro Thr Glu Leu Asn 
                85                  90                  95      


Cys Asp Asp Phe Lys Lys Gly Glu Arg Asp Gly Asp Phe Ile Cys Pro 
            100                 105                 110         


Asp Tyr Tyr Glu Ala Val Cys Gly Thr Asp Gly Lys Thr Tyr Asp Asn 
        115                 120                 125             


Arg Cys Ala Leu Cys Ala Glu Asn Ala Lys Thr Gly Ser Gln Ile Gly 
    130                 135                 140                 


Val Lys Ser Glu Gly Glu Cys Lys Ser Ser Asn Pro Glu Gln Asp Val 
145                 150                 155                 160 


Cys Ser Ala Phe Arg Pro Phe Val Arg Asp Gly Arg Leu Gly Cys Thr 
                165                 170                 175     


Arg Glu Asn Asp Pro Val Leu Gly Pro Asp Gly Lys Thr His Gly Asn 
            180                 185                 190         


Lys Cys Ala Met Cys Ala Glu Leu Phe Leu Lys Glu Ala Glu Asn Ala 
        195                 200                 205             


Lys Arg Glu Gly Glu Thr Arg Ile Arg Arg Asn Ala Glu Lys Asp Phe 
    210                 215                 220                 


Cys Lys Glu Tyr Glu Lys Gln Val Arg Asn Gly Arg Leu Phe Cys Thr 
225                 230                 235                 240 


Arg Glu Ser Asp Pro Val Arg Gly Pro Asp Gly Arg Met His Gly Asn 
                245                 250                 255     


Lys Cys Ala Leu Cys Ala Glu Ile Phe Lys Gln Arg Phe Ser Glu Glu 
            260                 265                 270         


Asn Ser Lys Thr Asp Gln Asn Leu Gly Lys Ala Glu Glu Lys Thr Lys 
        275                 280                 285             


Val Lys Arg Glu Ile Val Lys Leu Cys Ser Gln Tyr Gln Asn Gln Ala 
    290                 295                 300                 


Lys Asn Gly Ile Leu Phe Cys Thr Arg Glu Asn Asp Pro Ile Arg Gly 
305                 310                 315                 320 


Pro Asp Gly Lys Met His Gly Asn Leu Cys Ser Met Cys Gln Ala Tyr 
                325                 330                 335     


Phe Gln Ala Glu Asn Glu Glu Lys Lys Lys Ala Glu Ala Arg Ala Arg 
            340                 345                 350         


Asn Lys Arg Glu Ser Gly Lys Ala Thr Ser Tyr Ala Glu Leu Cys Ser 
        355                 360                 365             


Glu Tyr Arg Lys Leu Val Arg Asn Gly Lys Leu Ala Cys Thr Arg Glu 
    370                 375                 380                 


Asn Asp Pro Ile Gln Gly Pro Asp Gly Lys Val His Gly Asn Thr Cys 
385                 390                 395                 400 


Ser Met Cys Glu Val Phe Phe Gln Ala Glu Glu Glu Glu Lys Lys Lys 
                405                 410                 415     


Lys Glu Gly Lys Ser Arg Asn Lys Arg Gln Ser Lys Ser Thr Ala Ser 
            420                 425                 430         


Phe Glu Glu Leu Cys Ser Glu Tyr Arg Lys Ser Arg Lys Asn Gly Arg 
        435                 440                 445             


Leu Phe Cys Thr Arg Glu Asn Asp Pro Ile Gln Gly Pro Asp Gly Lys 
    450                 455                 460                 


Met His Gly Asn Thr Cys Ser Met Cys Glu Ala Phe Phe Gln Gln Glu 
465                 470                 475                 480 


Glu Arg Ala Arg Ala Lys Ala Lys Arg Glu Ala Ala Lys Glu Ile Cys 
                485                 490                 495     


Ser Glu Phe Arg Asp Gln Val Arg Asn Gly Thr Leu Ile Cys Thr Arg 
            500                 505                 510         


Glu His Asn Pro Val Arg Gly Pro Asp Gly Lys Met His Gly Asn Lys 
        515                 520                 525             


Cys Ala Met Cys Ala Ser Val Phe Lys Leu Glu Glu Glu Glu Lys Lys 
    530                 535                 540                 


Asn Asp Lys Glu Glu Lys Gly Lys Val Glu Ala Glu Lys Val Lys Arg 
545                 550                 555                 560 


Glu Ala Val Gln Glu Leu Cys Ser Glu Tyr Arg His Tyr Val Arg Asn 
                565                 570                 575     


Gly Arg Leu Pro Cys Thr Arg Glu Asn Asp Pro Ile Glu Gly Leu Asp 
            580                 585                 590         


Gly Lys Ile His Gly Asn Thr Cys Ser Met Cys Glu Ala Phe Phe Gln 
        595                 600                 605             


Gln Glu Ala Lys Glu Lys Glu Arg Ala Glu Pro Arg Ala Lys Val Lys 
    610                 615                 620                 


Arg Glu Ala Glu Lys Glu Thr Cys Asp Glu Phe Arg Arg Leu Leu Gln 
625                 630                 635                 640 


Asn Gly Lys Leu Phe Cys Thr Arg Glu Asn Asp Pro Val Arg Gly Pro 
                645                 650                 655     


Asp Gly Lys Thr His Gly Asn Lys Cys Ala Met Cys Lys Ala Val Phe 
            660                 665                 670         


Gln Lys Glu Asn Glu Glu Arg Lys Arg Lys Glu Glu Glu Asp Gln Arg 
        675                 680                 685             


Asn Ala Ala Gly His Gly Ser Ser Gly Gly Gly Gly Gly Asn Thr Gln 
    690                 695                 700                 


Asp Glu Cys Ala Glu Tyr Arg Glu Gln Met Lys Asn Gly Arg Leu Ser 
705                 710                 715                 720 


Cys Thr Arg Glu Ser Asp Pro Val Arg Asp Ala Asp Gly Lys Ser Tyr 
                725                 730                 735     


Asn Asn Gln Cys Thr Met Cys Lys Ala Lys Leu Glu Arg Glu Ala Glu 
            740                 745                 750         


Arg Lys Asn Glu Tyr Ser Arg Ser Arg Ser Asn Gly Thr Gly Ser Glu 
        755                 760                 765             


Ser Gly Lys Asp Thr Cys Asp Glu Phe Arg Ser Gln Met Lys Asn Gly 
    770                 775                 780                 


Lys Leu Ile Cys Thr Arg Glu Ser Asp Pro Val Arg Gly Pro Asp Gly 
785                 790                 795                 800 


Lys Thr His Gly Asn Lys Cys Thr Met Cys Lys Glu Lys Leu Glu Arg 
                805                 810                 815     


Glu Ala Ala Glu Lys Lys Lys Lys Glu Asp Glu Asp Arg Ser Asn Thr 
            820                 825                 830         


Gly Glu Arg Ser Asn Thr Gly Glu Arg Ser Asn Asp Lys Glu Asp Leu 
        835                 840                 845             


Cys Arg Glu Phe Arg Ser Met Gln Arg Asn Gly Lys Leu Ile Cys Thr 
    850                 855                 860                 


Arg Glu Asn Asn Pro Val Arg Gly Pro Tyr Gly Lys Met His Ile Asn 
865                 870                 875                 880 


Lys Cys Ala Met Cys Gln Ser Ile Phe Asp Arg Glu Ala Asn Glu Arg 
                885                 890                 895     


Lys Lys Lys Asp Glu Glu Lys Ser Ser Ser Lys Pro Ser Asn Asn Ala 
            900                 905                 910         


Lys Asp Glu Cys Ser Glu Phe Arg Asn Tyr Ile Arg Asn Asn Glu Leu 
        915                 920                 925             


Ile Cys Pro Arg Glu Asn Asp Pro Val His Gly Ala Asp Gly Lys Phe 
    930                 935                 940                 


Tyr Thr Asn Lys Cys Tyr Met Cys Arg Ala Val Phe Leu Thr Glu Ala 
945                 950                 955                 960 


Leu Glu Arg Ala Lys Leu Gln Glu Lys Pro Ser His Val Arg Ala Ser 
                965                 970                 975     


Gln Glu Glu Asp Ser Pro Asp Ser Phe Ser Ser Leu Asp Ser Glu Met 
            980                 985                 990         


Cys Lys Asp Tyr Arg Val Leu Pro  Arg Ile Gly Tyr Leu  Cys Pro Lys 
        995                 1000                 1005             


Asp Leu  Lys Pro Val Cys Gly  Asp Asp Gly Gln Thr  Tyr Asn Asn 
    1010                 1015                 1020             


Pro Cys  Met Leu Cys His Glu  Asn Leu Ile Arg Gln  Thr Asn Thr 
    1025                 1030                 1035             


His Ile  Arg Ser Thr Gly Lys  Cys Glu Glu Ser Ser  Thr Pro Gly 
    1040                 1045                 1050             


Thr Thr  Ala Ala Ser Met Pro  Pro Ser Asp Glu 
    1055                 1060                 


<210>  3777
<211>  1094
<212>  PRT
<213>  homo sapiens

<400>  3777

Met Lys Ile Ala Thr Val Ser Val Leu Leu Pro Leu Ala Leu Cys Leu 
1               5                   10                  15      


Ile Gln Asp Ala Ala Ser Lys Asn Glu Asp Gln Glu Met Cys His Glu 
            20                  25                  30          


Phe Gln Ala Phe Met Lys Asn Gly Lys Leu Phe Cys Pro Gln Asp Lys 
        35                  40                  45              


Lys Phe Phe Gln Ser Leu Asp Gly Ile Met Phe Ile Asn Lys Cys Ala 
    50                  55                  60                  


Thr Cys Lys Met Ile Leu Glu Lys Glu Ala Lys Ser Gln Lys Arg Ala 
65                  70                  75                  80  


Arg His Leu Ala Arg Ala Pro Lys Ala Thr Ala Pro Thr Glu Leu Asn 
                85                  90                  95      


Cys Asp Asp Phe Lys Lys Gly Glu Arg Asp Gly Asp Phe Ile Cys Pro 
            100                 105                 110         


Asp Tyr Tyr Glu Ala Val Cys Gly Thr Asp Gly Lys Thr Tyr Asp Asn 
        115                 120                 125             


Arg Cys Ala Leu Cys Ala Glu Asn Ala Lys Thr Gly Ser Gln Ile Gly 
    130                 135                 140                 


Val Lys Ser Glu Gly Glu Cys Lys Ser Ser Asn Pro Glu Gln Asp Val 
145                 150                 155                 160 


Cys Ser Ala Phe Arg Pro Phe Val Arg Asp Gly Arg Leu Gly Cys Thr 
                165                 170                 175     


Arg Glu Asn Asp Pro Val Leu Gly Pro Asp Gly Lys Thr His Gly Asn 
            180                 185                 190         


Lys Cys Ala Met Cys Ala Glu Leu Phe Leu Lys Glu Ala Glu Asn Ala 
        195                 200                 205             


Lys Arg Glu Gly Glu Thr Arg Ile Arg Arg Asn Ala Glu Lys Asp Phe 
    210                 215                 220                 


Cys Lys Glu Tyr Glu Lys Gln Val Arg Asn Gly Arg Leu Phe Cys Thr 
225                 230                 235                 240 


Arg Glu Ser Asp Pro Val Arg Gly Pro Asp Gly Arg Met His Gly Asn 
                245                 250                 255     


Lys Cys Ala Leu Cys Ala Glu Ile Phe Lys Gln Arg Phe Ser Glu Glu 
            260                 265                 270         


Asn Ser Lys Thr Asp Gln Asn Leu Gly Lys Ala Glu Glu Lys Thr Lys 
        275                 280                 285             


Val Lys Arg Glu Ile Val Lys Leu Cys Ser Gln Tyr Gln Asn Gln Ala 
    290                 295                 300                 


Lys Asn Gly Ile Leu Phe Cys Thr Arg Glu Asn Asp Pro Ile Arg Gly 
305                 310                 315                 320 


Pro Asp Gly Lys Met His Gly Asn Leu Cys Ser Met Cys Gln Ala Tyr 
                325                 330                 335     


Phe Gln Ala Glu Asn Glu Glu Lys Lys Lys Ala Glu Ala Arg Ala Arg 
            340                 345                 350         


Asn Lys Arg Glu Ser Gly Lys Ala Thr Ser Tyr Ala Glu Leu Cys Ser 
        355                 360                 365             


Glu Tyr Arg Lys Leu Val Arg Asn Gly Lys Leu Ala Cys Thr Arg Glu 
    370                 375                 380                 


Asn Asp Pro Ile Gln Gly Pro Asp Gly Lys Val His Gly Asn Thr Cys 
385                 390                 395                 400 


Ser Met Cys Glu Val Phe Phe Gln Ala Glu Glu Glu Glu Lys Lys Lys 
                405                 410                 415     


Lys Glu Gly Lys Ser Arg Asn Lys Arg Gln Ser Lys Ser Thr Ala Ser 
            420                 425                 430         


Phe Glu Glu Leu Cys Ser Glu Tyr Arg Lys Ser Arg Lys Asn Gly Arg 
        435                 440                 445             


Leu Phe Cys Thr Arg Glu Asn Asp Pro Ile Gln Gly Pro Asp Gly Lys 
    450                 455                 460                 


Met His Gly Asn Thr Cys Ser Met Cys Glu Ala Phe Phe Gln Gln Glu 
465                 470                 475                 480 


Glu Arg Ala Arg Ala Lys Ala Lys Arg Glu Ala Ala Lys Glu Ile Cys 
                485                 490                 495     


Ser Glu Phe Arg Asp Gln Val Arg Asn Gly Thr Leu Ile Cys Thr Arg 
            500                 505                 510         


Glu His Asn Pro Val Arg Gly Pro Asp Gly Lys Met His Gly Asn Lys 
        515                 520                 525             


Cys Ala Met Cys Ala Ser Val Phe Lys Leu Glu Glu Glu Glu Lys Lys 
    530                 535                 540                 


Asn Asp Lys Glu Glu Lys Gly Lys Val Glu Ala Glu Lys Val Lys Arg 
545                 550                 555                 560 


Glu Ala Val Gln Glu Leu Cys Ser Glu Tyr Arg His Tyr Val Arg Asn 
                565                 570                 575     


Gly Arg Leu Pro Cys Thr Arg Glu Asn Asp Pro Ile Glu Gly Leu Asp 
            580                 585                 590         


Gly Lys Ile His Gly Asn Thr Cys Ser Met Cys Glu Ala Phe Phe Gln 
        595                 600                 605             


Gln Glu Ala Lys Glu Lys Glu Arg Ala Glu Pro Arg Ala Lys Val Lys 
    610                 615                 620                 


Arg Glu Ala Glu Lys Glu Thr Cys Asp Glu Phe Arg Arg Leu Leu Gln 
625                 630                 635                 640 


Asn Gly Lys Leu Phe Cys Thr Arg Glu Asn Asp Pro Val Arg Gly Pro 
                645                 650                 655     


Asp Gly Lys Thr His Gly Asn Lys Cys Ala Met Cys Lys Ala Val Phe 
            660                 665                 670         


Gln Lys Glu Asn Glu Glu Arg Lys Arg Lys Glu Glu Glu Asp Gln Arg 
        675                 680                 685             


Asn Ala Ala Gly His Gly Ser Ser Gly Gly Gly Gly Gly Asn Thr Gln 
    690                 695                 700                 


Asp Glu Cys Ala Glu Tyr Arg Glu Gln Met Lys Asn Gly Arg Leu Ser 
705                 710                 715                 720 


Cys Thr Arg Glu Ser Asp Pro Val Arg Asp Ala Asp Gly Lys Ser Tyr 
                725                 730                 735     


Asn Asn Gln Cys Thr Met Cys Lys Ala Lys Leu Glu Arg Glu Ala Glu 
            740                 745                 750         


Arg Lys Asn Glu Tyr Ser Arg Ser Arg Ser Asn Gly Thr Gly Ser Glu 
        755                 760                 765             


Ser Gly Lys Asp Thr Cys Asp Glu Phe Arg Ser Gln Met Lys Asn Gly 
    770                 775                 780                 


Lys Leu Ile Cys Thr Arg Glu Ser Asp Pro Val Arg Gly Pro Asp Gly 
785                 790                 795                 800 


Lys Thr His Gly Asn Lys Cys Thr Met Cys Lys Glu Lys Leu Glu Arg 
                805                 810                 815     


Glu Ala Ala Glu Lys Lys Lys Lys Glu Asp Glu Asp Arg Ser Asn Thr 
            820                 825                 830         


Gly Glu Arg Ser Asn Thr Gly Glu Arg Ser Asn Asp Lys Glu Asp Leu 
        835                 840                 845             


Cys Arg Glu Phe Arg Ser Met Gln Arg Asn Gly Lys Leu Ile Cys Thr 
    850                 855                 860                 


Arg Glu Asn Asn Pro Val Arg Gly Pro Tyr Gly Lys Met His Ile Asn 
865                 870                 875                 880 


Lys Cys Ala Met Cys Gln Ser Ile Phe Asp Arg Glu Ala Asn Glu Arg 
                885                 890                 895     


Lys Lys Lys Asp Glu Glu Lys Ser Ser Ser Lys Pro Ser Asn Asn Ala 
            900                 905                 910         


Lys Asp Gln Cys Arg Gln Val Gln Asn Glu Ala Glu Asp Ala Lys Phe 
        915                 920                 925             


Arg Gln Pro Gly Arg Ser Leu Ala Ser Val Ala Arg Met Ser Thr Asp 
    930                 935                 940                 


Glu Cys Ser Glu Phe Arg Asn Tyr Ile Arg Asn Asn Glu Leu Ile Cys 
945                 950                 955                 960 


Pro Arg Glu Asn Asp Pro Val His Gly Ala Asp Gly Lys Phe Tyr Thr 
                965                 970                 975     


Asn Lys Cys Tyr Met Cys Arg Ala Val Phe Leu Thr Glu Ala Leu Glu 
            980                 985                 990         


Arg Ala Lys Leu Gln Glu Lys Pro  Ser His Val Arg Ala  Ser Gln Glu 
        995                 1000                 1005             


Glu Asp  Ser Pro Asp Ser Phe  Ser Ser Leu Asp Ser  Glu Met Cys 
    1010                 1015                 1020             


Lys Asp  Tyr Arg Val Leu Pro  Arg Ile Gly Tyr Leu  Cys Pro Lys 
    1025                 1030                 1035             


Asp Leu  Lys Pro Val Cys Gly  Asp Asp Gly Gln Thr  Tyr Asn Asn 
    1040                 1045                 1050             


Pro Cys  Met Leu Cys His Glu  Asn Leu Ile Arg Gln  Thr Asn Thr 
    1055                 1060                 1065             


His Ile  Arg Ser Thr Gly Lys  Cys Glu Glu Ser Ser  Thr Pro Gly 
    1070                 1075                 1080             


Thr Thr  Ala Ala Ser Met Pro  Pro Ser Asp Glu 
    1085                 1090                 


<210>  3778
<211>  916
<212>  PRT
<213>  homo sapiens

<400>  3778

Met Lys Ile Ala Thr Val Ser Val Leu Leu Pro Leu Ala Leu Cys Leu 
1               5                   10                  15      


Ile Gln Asp Ala Ala Ser Lys Asn Glu Asp Gln Glu Met Cys His Glu 
            20                  25                  30          


Phe Gln Ala Phe Met Lys Asn Gly Lys Leu Phe Cys Pro Gln Asp Lys 
        35                  40                  45              


Lys Phe Phe Gln Ser Leu Asp Gly Ile Met Phe Ile Asn Lys Cys Ala 
    50                  55                  60                  


Thr Cys Lys Met Ile Leu Glu Lys Glu Ala Lys Ser Gln Lys Arg Ala 
65                  70                  75                  80  


Arg His Leu Ala Arg Ala Pro Lys Ala Thr Ala Pro Thr Glu Leu Asn 
                85                  90                  95      


Cys Asp Asp Phe Lys Lys Gly Glu Arg Asp Gly Asp Phe Ile Cys Pro 
            100                 105                 110         


Asp Tyr Tyr Glu Ala Val Cys Gly Thr Asp Gly Lys Thr Tyr Asp Asn 
        115                 120                 125             


Arg Cys Ala Leu Cys Ala Glu Asn Ala Lys Thr Gly Ser Gln Ile Gly 
    130                 135                 140                 


Val Lys Ser Glu Gly Glu Cys Lys Ser Ser Asn Pro Glu Gln Asp Val 
145                 150                 155                 160 


Cys Ser Ala Phe Arg Pro Phe Val Arg Asp Gly Arg Leu Gly Cys Thr 
                165                 170                 175     


Arg Glu Asn Asp Pro Val Leu Gly Pro Asp Gly Lys Thr His Gly Asn 
            180                 185                 190         


Lys Cys Ala Met Cys Ala Glu Leu Phe Leu Lys Glu Ala Glu Asn Ala 
        195                 200                 205             


Lys Arg Glu Gly Glu Thr Arg Ile Arg Arg Asn Ala Glu Lys Asp Phe 
    210                 215                 220                 


Cys Lys Glu Tyr Glu Lys Gln Val Arg Asn Gly Arg Leu Phe Cys Thr 
225                 230                 235                 240 


Arg Glu Ser Asp Pro Val Arg Gly Pro Asp Gly Arg Met His Gly Asn 
                245                 250                 255     


Lys Cys Ala Leu Cys Ala Glu Ile Phe Lys Gln Arg Phe Ser Glu Glu 
            260                 265                 270         


Asn Ser Lys Thr Asp Gln Asn Leu Gly Lys Ala Glu Glu Lys Thr Lys 
        275                 280                 285             


Val Lys Arg Glu Ile Val Lys Leu Cys Ser Gln Tyr Gln Asn Gln Ala 
    290                 295                 300                 


Lys Asn Gly Ile Leu Phe Cys Thr Arg Glu Asn Asp Pro Ile Arg Gly 
305                 310                 315                 320 


Pro Asp Gly Lys Met His Gly Asn Leu Cys Ser Met Cys Gln Ala Tyr 
                325                 330                 335     


Phe Gln Ala Glu Asn Glu Glu Lys Lys Lys Ala Glu Ala Arg Ala Arg 
            340                 345                 350         


Asn Lys Arg Glu Ser Gly Lys Ala Thr Ser Tyr Ala Glu Leu Cys Ser 
        355                 360                 365             


Glu Tyr Arg Lys Leu Val Arg Asn Gly Lys Leu Ala Cys Thr Arg Glu 
    370                 375                 380                 


Asn Asp Pro Ile Gln Gly Pro Asp Gly Lys Val His Gly Asn Thr Cys 
385                 390                 395                 400 


Ser Met Cys Glu Val Phe Phe Gln Ala Glu Glu Glu Glu Lys Lys Lys 
                405                 410                 415     


Lys Glu Gly Lys Ser Arg Asn Lys Arg Gln Ser Lys Ser Thr Ala Ser 
            420                 425                 430         


Phe Glu Glu Leu Cys Ser Glu Tyr Arg Lys Ser Arg Lys Asn Gly Arg 
        435                 440                 445             


Leu Phe Cys Thr Arg Glu Asn Asp Pro Ile Gln Gly Pro Asp Gly Lys 
    450                 455                 460                 


Met His Gly Asn Thr Cys Ser Met Cys Glu Ala Phe Phe Gln Gln Glu 
465                 470                 475                 480 


Glu Arg Ala Arg Ala Lys Ala Lys Arg Glu Ala Ala Lys Glu Ile Cys 
                485                 490                 495     


Ser Glu Phe Arg Asp Gln Val Arg Asn Gly Thr Leu Ile Cys Thr Arg 
            500                 505                 510         


Glu His Asn Pro Val Arg Gly Pro Asp Gly Lys Met His Gly Asn Lys 
        515                 520                 525             


Cys Ala Met Cys Ala Ser Val Phe Lys Leu Glu Glu Glu Glu Lys Lys 
    530                 535                 540                 


Asn Asp Lys Glu Glu Lys Gly Lys Val Glu Ala Glu Lys Val Lys Arg 
545                 550                 555                 560 


Glu Ala Val Gln Glu Leu Cys Ser Glu Tyr Arg His Tyr Val Arg Asn 
                565                 570                 575     


Gly Arg Leu Pro Cys Thr Arg Glu Asn Asp Pro Ile Glu Gly Leu Asp 
            580                 585                 590         


Gly Lys Ile His Gly Asn Thr Cys Ser Met Cys Glu Ala Phe Phe Gln 
        595                 600                 605             


Gln Glu Ala Lys Glu Lys Glu Arg Ala Glu Pro Arg Ala Lys Val Lys 
    610                 615                 620                 


Arg Glu Ala Glu Lys Glu Thr Cys Asp Glu Phe Arg Arg Leu Leu Gln 
625                 630                 635                 640 


Asn Gly Lys Leu Phe Cys Thr Arg Glu Asn Asp Pro Val Arg Gly Pro 
                645                 650                 655     


Asp Gly Lys Thr His Gly Asn Lys Cys Ala Met Cys Lys Ala Val Phe 
            660                 665                 670         


Gln Lys Glu Asn Glu Glu Arg Lys Arg Lys Glu Glu Glu Asp Gln Arg 
        675                 680                 685             


Asn Ala Ala Gly His Gly Ser Ser Gly Gly Gly Gly Gly Asn Thr Gln 
    690                 695                 700                 


Asp Glu Cys Ala Glu Tyr Arg Glu Gln Met Lys Asn Gly Arg Leu Ser 
705                 710                 715                 720 


Cys Thr Arg Glu Ser Asp Pro Val Arg Asp Ala Asp Gly Lys Ser Tyr 
                725                 730                 735     


Asn Asn Gln Cys Thr Met Cys Lys Ala Lys Leu Glu Arg Glu Ala Glu 
            740                 745                 750         


Arg Lys Asn Glu Tyr Ser Arg Ser Arg Ser Asn Gly Thr Gly Ser Glu 
        755                 760                 765             


Ser Gly Lys Asp Thr Cys Asp Glu Phe Arg Ser Gln Met Lys Asn Gly 
    770                 775                 780                 


Lys Leu Ile Cys Thr Arg Glu Ser Asp Pro Val Arg Gly Pro Asp Gly 
785                 790                 795                 800 


Lys Thr His Gly Asn Lys Cys Thr Met Cys Lys Glu Lys Leu Glu Arg 
                805                 810                 815     


Glu Ala Ala Glu Lys Lys Lys Lys Glu Asp Glu Asp Arg Ser Asn Thr 
            820                 825                 830         


Gly Glu Arg Ser Asn Thr Gly Glu Arg Ser Asn Asp Lys Glu Asp Leu 
        835                 840                 845             


Cys Arg Glu Phe Arg Ser Met Gln Arg Asn Gly Lys Leu Ile Cys Thr 
    850                 855                 860                 


Arg Glu Asn Asn Pro Val Arg Gly Pro Tyr Gly Lys Met His Ile Asn 
865                 870                 875                 880 


Lys Cys Ala Met Cys Gln Ser Ile Phe Asp Arg Glu Ala Asn Glu Arg 
                885                 890                 895     


Lys Lys Lys Asp Glu Glu Lys Ser Ser Ser Lys Pro Ser Asn Asn Ala 
            900                 905                 910         


Lys Val Ile Tyr 
        915     


<210>  3779
<211>  519
<212>  PRT
<213>  homo sapiens

<400>  3779

Met Asp Ala Val Leu Glu Pro Phe Pro Ala Asp Arg Leu Phe Pro Gly 
1               5                   10                  15      


Ser Ser Phe Leu Asp Leu Gly Asp Leu Asn Glu Ser Asp Phe Leu Asn 
            20                  25                  30          


Asn Ala His Phe Pro Glu His Leu Asp His Phe Thr Glu Asn Met Glu 
        35                  40                  45              


Asp Phe Ser Asn Asp Leu Phe Ser Ser Phe Phe Asp Asp Pro Val Leu 
    50                  55                  60                  


Asp Glu Lys Ser Pro Leu Leu Asp Met Glu Leu Asp Ser Pro Thr Pro 
65                  70                  75                  80  


Gly Ile Gln Ala Glu His Ser Tyr Ser Leu Ser Gly Asp Ser Ala Pro 
                85                  90                  95      


Gln Ser Pro Leu Val Pro Ile Lys Met Glu Asp Thr Thr Gln Asp Ala 
            100                 105                 110         


Glu His Gly Ala Trp Ala Leu Gly His Lys Leu Cys Ser Ile Met Val 
        115                 120                 125             


Lys Gln Glu Gln Ser Pro Glu Leu Pro Val Asp Pro Leu Ala Ala Pro 
    130                 135                 140                 


Ser Ala Met Ala Ala Ala Ala Ala Met Ala Thr Thr Pro Leu Leu Gly 
145                 150                 155                 160 


Leu Ser Pro Leu Ser Arg Leu Pro Ile Pro His Gln Ala Pro Gly Glu 
                165                 170                 175     


Met Thr Gln Leu Pro Val Ile Lys Ala Glu Pro Leu Glu Val Asn Gln 
            180                 185                 190         


Phe Leu Lys Val Thr Pro Glu Asp Leu Val Gln Met Pro Pro Thr Pro 
        195                 200                 205             


Pro Ser Ser His Gly Ser Asp Ser Asp Gly Ser Gln Ser Pro Arg Ser 
    210                 215                 220                 


Leu Pro Pro Ser Ser Pro Val Arg Pro Met Ala Arg Ser Ser Thr Ala 
225                 230                 235                 240 


Ile Ser Thr Ser Pro Leu Leu Thr Ala Pro His Lys Leu Gln Gly Thr 
                245                 250                 255     


Ser Gly Pro Leu Leu Leu Thr Glu Glu Glu Lys Arg Thr Leu Ile Ala 
            260                 265                 270         


Glu Gly Tyr Pro Ile Pro Thr Lys Leu Pro Leu Thr Lys Ala Glu Glu 
        275                 280                 285             


Lys Ala Leu Lys Arg Val Arg Arg Lys Ile Lys Asn Lys Ile Ser Ala 
    290                 295                 300                 


Gln Glu Ser Arg Arg Lys Lys Lys Glu Tyr Val Glu Cys Leu Glu Lys 
305                 310                 315                 320 


Lys Val Glu Thr Phe Thr Ser Glu Asn Asn Glu Leu Trp Lys Lys Val 
                325                 330                 335     


Glu Thr Leu Glu Asn Ala Asn Arg Thr Leu Leu Gln Gln Leu Gln Lys 
            340                 345                 350         


Leu Gln Thr Leu Val Thr Asn Lys Ile Ser Arg Pro Tyr Lys Met Ala 
        355                 360                 365             


Ala Thr Gln Thr Gly Thr Cys Leu Met Val Ala Ala Leu Cys Phe Val 
    370                 375                 380                 


Leu Val Leu Gly Ser Leu Val Pro Cys Leu Pro Glu Phe Ser Ser Gly 
385                 390                 395                 400 


Ser Gln Thr Val Lys Glu Asp Pro Leu Ala Ala Asp Gly Val Tyr Thr 
                405                 410                 415     


Ala Ser Gln Met Pro Ser Arg Ser Leu Leu Phe Tyr Asp Asp Gly Ala 
            420                 425                 430         


Gly Leu Trp Glu Asp Gly Arg Ser Thr Leu Leu Pro Met Glu Pro Pro 
        435                 440                 445             


Asp Gly Trp Glu Ile Asn Pro Gly Gly Pro Ala Glu Gln Arg Pro Arg 
    450                 455                 460                 


Asp His Leu Gln His Asp His Leu Asp Ser Thr His Glu Thr Thr Lys 
465                 470                 475                 480 


Tyr Leu Ser Glu Ala Trp Pro Lys Asp Gly Gly Asn Gly Thr Ser Pro 
                485                 490                 495     


Asp Phe Ser His Ser Lys Glu Trp Phe His Asp Arg Asp Leu Gly Pro 
            500                 505                 510         


Asn Thr Thr Ile Lys Leu Ser 
        515                 


<210>  3780
<211>  208
<212>  PRT
<213>  homo sapiens

<400>  3780

Met Gln Ala Thr Ala Asp Ser Thr Lys Met Asp Cys Val Trp Ser Asn 
1               5                   10                  15      


Trp Lys Ser Gln Ala Ile Asp Leu Leu Tyr Trp Arg Asp Ile Lys Gln 
            20                  25                  30          


Thr Gly Ile Val Phe Gly Ser Phe Leu Leu Leu Leu Phe Ser Leu Thr 
        35                  40                  45              


Gln Phe Ser Val Val Ser Val Val Ala Tyr Leu Ala Leu Ala Ala Leu 
    50                  55                  60                  


Ser Ala Thr Ile Ser Phe Arg Ile Tyr Lys Ser Val Leu Gln Ala Val 
65                  70                  75                  80  


Gln Lys Thr Asp Glu Gly His Pro Phe Lys Ala Tyr Leu Glu Leu Glu 
                85                  90                  95      


Ile Thr Leu Ser Gln Glu Gln Ile Gln Lys Tyr Thr Asp Cys Leu Gln 
            100                 105                 110         


Phe Tyr Val Asn Ser Thr Leu Lys Glu Leu Arg Arg Leu Phe Leu Val 
        115                 120                 125             


Gln Asp Leu Val Asp Ser Leu Lys Phe Ala Val Leu Met Trp Leu Leu 
    130                 135                 140                 


Thr Tyr Val Gly Ala Leu Phe Asn Gly Leu Thr Leu Leu Leu Met Ala 
145                 150                 155                 160 


Val Val Ser Met Phe Thr Leu Pro Val Val Tyr Val Lys His Gln Ala 
                165                 170                 175     


Gln Ile Asp Gln Tyr Leu Gly Leu Val Arg Thr His Ile Asn Ala Val 
            180                 185                 190         


Val Ala Lys Ile Gln Ala Lys Ile Pro Gly Ala Lys Arg His Ala Glu 
        195                 200                 205             


<210>  3781
<211>  577
<212>  PRT
<213>  homo sapiens

<400>  3781

Met Asn Lys Leu Tyr Ile Gly Asn Leu Asn Glu Ser Val Thr Pro Ala 
1               5                   10                  15      


Asp Leu Glu Lys Val Phe Ala Glu His Lys Ile Ser Tyr Ser Gly Gln 
            20                  25                  30          


Phe Leu Val Lys Ser Gly Tyr Ala Phe Val Asp Cys Pro Asp Glu His 
        35                  40                  45              


Trp Ala Met Lys Ala Ile Glu Thr Phe Ser Gly Lys Val Glu Leu Gln 
    50                  55                  60                  


Gly Lys Arg Leu Glu Ile Glu His Ser Val Pro Lys Lys Gln Arg Ser 
65                  70                  75                  80  


Arg Lys Ile Gln Ile Arg Asn Ile Pro Pro Gln Leu Arg Trp Glu Val 
                85                  90                  95      


Leu Asp Ser Leu Leu Ala Gln Tyr Gly Thr Val Glu Asn Cys Glu Gln 
            100                 105                 110         


Val Asn Thr Glu Ser Glu Thr Ala Val Val Asn Val Thr Tyr Ser Asn 
        115                 120                 125             


Arg Glu Gln Thr Arg Gln Ala Ile Met Lys Leu Asn Gly His Gln Leu 
    130                 135                 140                 


Glu Asn His Ala Leu Lys Val Ser Tyr Ile Pro Asp Glu Gln Ile Ala 
145                 150                 155                 160 


Gln Gly Pro Glu Asn Gly Arg Arg Gly Gly Phe Gly Ser Arg Gly Gln 
                165                 170                 175     


Pro Arg Gln Gly Ser Pro Val Ala Ala Gly Ala Pro Ala Lys Gln Gln 
            180                 185                 190         


Gln Val Asp Ile Pro Leu Arg Leu Leu Val Pro Thr Gln Tyr Val Gly 
        195                 200                 205             


Ala Ile Ile Gly Lys Glu Gly Ala Thr Ile Arg Asn Ile Thr Lys Gln 
    210                 215                 220                 


Thr Gln Ser Lys Ile Asp Val His Arg Lys Glu Asn Ala Gly Ala Ala 
225                 230                 235                 240 


Glu Lys Ala Ile Ser Val His Ser Thr Pro Glu Gly Cys Ser Ser Ala 
                245                 250                 255     


Cys Lys Met Ile Leu Glu Ile Met His Lys Glu Ala Lys Asp Thr Lys 
            260                 265                 270         


Thr Ala Asp Glu Val Pro Leu Lys Ile Leu Ala His Asn Asn Phe Val 
        275                 280                 285             


Gly Arg Leu Ile Gly Lys Glu Gly Arg Asn Leu Lys Lys Val Glu Gln 
    290                 295                 300                 


Asp Thr Glu Thr Lys Ile Thr Ile Ser Ser Leu Gln Asp Leu Thr Leu 
305                 310                 315                 320 


Tyr Asn Pro Glu Arg Thr Ile Thr Val Lys Gly Ala Ile Glu Asn Cys 
                325                 330                 335     


Cys Arg Ala Glu Gln Glu Ile Met Lys Lys Val Arg Glu Ala Tyr Glu 
            340                 345                 350         


Asn Asp Val Ala Ala Met Ser Leu Gln Ser His Leu Ile Pro Gly Leu 
        355                 360                 365             


Asn Leu Ala Ala Val Gly Leu Phe Pro Ala Ser Ser Ser Ala Val Pro 
    370                 375                 380                 


Pro Pro Pro Ser Ser Val Thr Gly Ala Ala Pro Tyr Ser Ser Phe Met 
385                 390                 395                 400 


Gln Ala Pro Glu Gln Glu Met Val Gln Val Phe Ile Pro Ala Gln Ala 
                405                 410                 415     


Val Gly Ala Ile Ile Gly Lys Lys Gly Gln His Ile Lys Gln Leu Ser 
            420                 425                 430         


Arg Phe Ala Ser Ala Ser Ile Lys Ile Ala Pro Pro Glu Thr Pro Asp 
        435                 440                 445             


Ser Lys Val Arg Met Val Ile Ile Thr Gly Pro Pro Glu Ala Gln Phe 
    450                 455                 460                 


Lys Ala Gln Gly Arg Ile Tyr Gly Lys Leu Lys Glu Glu Asn Phe Phe 
465                 470                 475                 480 


Gly Pro Lys Glu Glu Val Lys Leu Glu Thr His Ile Arg Val Pro Ala 
                485                 490                 495     


Ser Ala Ala Gly Arg Val Ile Gly Lys Gly Gly Lys Thr Val Asn Glu 
            500                 505                 510         


Leu Gln Asn Leu Thr Ala Ala Glu Val Val Val Pro Arg Asp Gln Thr 
        515                 520                 525             


Pro Asp Glu Asn Asp Gln Val Ile Val Lys Ile Ile Gly His Phe Tyr 
    530                 535                 540                 


Ala Ser Gln Met Ala Gln Arg Lys Ile Arg Asp Ile Leu Ala Gln Val 
545                 550                 555                 560 


Lys Gln Gln His Gln Lys Gly Gln Ser Asn Gln Ala Gln Ala Arg Arg 
                565                 570                 575     


Lys 
    


<210>  3782
<211>  438
<212>  PRT
<213>  homo sapiens

<400>  3782

Met Asn Lys Leu Tyr Ile Gly Asn Leu Asn Glu Ser Val Thr Pro Ala 
1               5                   10                  15      


Asp Leu Glu Lys Val Phe Ala Glu His Lys Ile Ser Tyr Ser Gly Gln 
            20                  25                  30          


Phe Leu Val Lys Ser Gly Tyr Ala Phe Val Asp Cys Pro Asp Glu His 
        35                  40                  45              


Trp Ala Met Lys Ala Ile Glu Thr Phe Ser Gly Lys Val Glu Leu Gln 
    50                  55                  60                  


Gly Lys Arg Leu Glu Ile Glu His Ser Val Pro Lys Lys Gln Arg Ser 
65                  70                  75                  80  


Arg Lys Ile Gln Ile Arg Asn Ile Pro Pro Gln Leu Arg Trp Glu Val 
                85                  90                  95      


Leu Asp Ser Leu Leu Ala Gln Tyr Gly Thr Val Glu Asn Cys Glu Gln 
            100                 105                 110         


Val Asn Thr Glu Ser Glu Thr Ala Val Val Asn Val Thr Tyr Ser Asn 
        115                 120                 125             


Arg Glu Gln Thr Arg Gln Ala Asp Glu Val Pro Leu Lys Ile Leu Ala 
    130                 135                 140                 


His Asn Asn Phe Val Gly Arg Leu Ile Gly Lys Glu Gly Arg Asn Leu 
145                 150                 155                 160 


Lys Lys Val Glu Gln Asp Thr Glu Thr Lys Ile Thr Ile Ser Ser Leu 
                165                 170                 175     


Gln Asp Leu Thr Leu Tyr Asn Pro Glu Arg Thr Ile Thr Val Lys Gly 
            180                 185                 190         


Ala Ile Glu Asn Cys Cys Arg Ala Glu Gln Glu Ile Met Lys Lys Val 
        195                 200                 205             


Arg Glu Ala Tyr Glu Asn Asp Val Ala Ala Met Ser Leu Gln Ser His 
    210                 215                 220                 


Leu Ile Pro Gly Leu Asn Leu Ala Ala Val Gly Leu Phe Pro Ala Ser 
225                 230                 235                 240 


Ser Ser Ala Val Pro Pro Pro Pro Ser Ser Val Thr Gly Ala Ala Pro 
                245                 250                 255     


Tyr Ser Ser Phe Met Gln Ala Pro Glu Gln Glu Met Val Gln Val Phe 
            260                 265                 270         


Ile Pro Ala Gln Ala Val Gly Ala Ile Ile Gly Lys Lys Gly Gln His 
        275                 280                 285             


Ile Lys Gln Leu Ser Arg Phe Ala Ser Ala Ser Ile Lys Ile Ala Pro 
    290                 295                 300                 


Pro Glu Thr Pro Asp Ser Lys Val Arg Met Val Ile Ile Thr Gly Pro 
305                 310                 315                 320 


Pro Glu Ala Gln Phe Lys Ala Gln Gly Arg Ile Tyr Gly Lys Leu Lys 
                325                 330                 335     


Glu Glu Asn Phe Phe Gly Pro Lys Glu Glu Val Lys Leu Glu Thr His 
            340                 345                 350         


Ile Arg Val Pro Ala Ser Ala Ala Gly Arg Val Ile Gly Lys Gly Gly 
        355                 360                 365             


Lys Thr Val Asn Glu Leu Gln Asn Leu Thr Ala Ala Glu Val Val Val 
    370                 375                 380                 


Pro Arg Asp Gln Thr Pro Asp Glu Asn Asp Gln Val Ile Val Lys Ile 
385                 390                 395                 400 


Ile Gly His Phe Tyr Ala Ser Gln Met Ala Gln Arg Lys Ile Arg Asp 
                405                 410                 415     


Ile Leu Ala Gln Val Lys Gln Gln His Gln Lys Gly Gln Ser Asn Gln 
            420                 425                 430         


Ala Gln Ala Arg Arg Lys 
        435             


<210>  3783
<211>  311
<212>  PRT
<213>  homo sapiens

<400>  3783

Met Gln Asn Tyr Lys Tyr Asp Lys Ala Ile Val Pro Glu Ser Lys Asn 
1               5                   10                  15      


Gly Gly Ser Pro Ala Leu Asn Asn Asn Pro Arg Arg Ser Gly Ser Lys 
            20                  25                  30          


Arg Val Leu Leu Ile Cys Leu Asp Leu Phe Cys Leu Phe Met Ala Gly 
        35                  40                  45              


Leu Pro Phe Leu Ile Ile Glu Thr Ser Thr Ile Lys Pro Tyr His Arg 
    50                  55                  60                  


Gly Phe Tyr Cys Asn Asp Glu Ser Ile Lys Tyr Pro Leu Lys Thr Gly 
65                  70                  75                  80  


Glu Thr Ile Asn Asp Ala Val Leu Cys Ala Val Gly Ile Val Ile Ala 
                85                  90                  95      


Ile Leu Ala Ile Ile Thr Gly Glu Phe Tyr Arg Ile Tyr Tyr Leu Lys 
            100                 105                 110         


Lys Ser Arg Ser Thr Ile Gln Asn Pro Tyr Val Ala Ala Leu Tyr Lys 
        115                 120                 125             


Gln Val Gly Cys Phe Leu Phe Gly Cys Ala Ile Ser Gln Ser Phe Thr 
    130                 135                 140                 


Asp Ile Ala Lys Val Ser Ile Gly Arg Leu Arg Pro His Phe Leu Ser 
145                 150                 155                 160 


Val Cys Asn Pro Asp Phe Ser Gln Ile Asn Cys Ser Glu Gly Tyr Ile 
                165                 170                 175     


Gln Asn Tyr Arg Cys Arg Gly Asp Asp Ser Lys Val Gln Glu Ala Arg 
            180                 185                 190         


Lys Ser Phe Phe Ser Gly His Ala Ser Phe Ser Met Tyr Thr Met Leu 
        195                 200                 205             


Tyr Leu Val Leu Tyr Leu Gln Ala Arg Phe Thr Trp Arg Gly Ala Arg 
    210                 215                 220                 


Leu Leu Arg Pro Leu Leu Gln Phe Thr Leu Ile Met Met Ala Phe Tyr 
225                 230                 235                 240 


Thr Gly Leu Ser Arg Val Ser Asp His Lys His His Pro Ser Asp Val 
                245                 250                 255     


Leu Ala Gly Phe Ala Gln Gly Ala Leu Val Ala Cys Cys Ile Val Phe 
            260                 265                 270         


Phe Val Ser Asp Leu Phe Lys Thr Lys Thr Thr Leu Ser Leu Pro Ala 
        275                 280                 285             


Pro Ala Ile Arg Lys Glu Ile Leu Ser Pro Val Asp Ile Ile Asp Arg 
    290                 295                 300                 


Asn Asn His His Asn Met Met 
305                 310     


<210>  3784
<211>  314
<212>  PRT
<213>  homo sapiens

<400>  3784

Met Gly Ile Gly Arg Ser Glu Gly Gly Arg Arg Gly Ala Ala Leu Gly 
1               5                   10                  15      


Val Leu Leu Ala Leu Gly Ala Ala Leu Leu Ala Val Gly Ser Ala Ser 
            20                  25                  30          


Glu Tyr Asp Tyr Val Ser Phe Gln Ser Asp Ile Gly Pro Tyr Gln Ser 
        35                  40                  45              


Gly Arg Phe Tyr Thr Lys Pro Pro Gln Cys Val Asp Ile Pro Ala Asp 
    50                  55                  60                  


Leu Arg Leu Cys His Asn Val Gly Tyr Lys Lys Met Val Leu Pro Asn 
65                  70                  75                  80  


Leu Leu Glu His Glu Thr Met Ala Glu Val Lys Gln Gln Ala Ser Ser 
                85                  90                  95      


Trp Val Pro Leu Leu Asn Lys Asn Cys His Ala Gly Thr Gln Val Phe 
            100                 105                 110         


Leu Cys Ser Leu Phe Ala Pro Val Cys Leu Asp Arg Pro Ile Tyr Pro 
        115                 120                 125             


Cys Arg Trp Leu Cys Glu Ala Val Arg Asp Ser Cys Glu Pro Val Met 
    130                 135                 140                 


Gln Phe Phe Gly Phe Tyr Trp Pro Glu Met Leu Lys Cys Asp Lys Phe 
145                 150                 155                 160 


Pro Glu Gly Asp Val Cys Ile Ala Met Thr Pro Pro Asn Ala Thr Glu 
                165                 170                 175     


Ala Ser Lys Pro Gln Gly Thr Thr Val Cys Pro Pro Cys Asp Asn Glu 
            180                 185                 190         


Leu Lys Ser Glu Ala Ile Ile Glu His Leu Cys Ala Ser Glu Phe Ala 
        195                 200                 205             


Leu Arg Met Lys Ile Lys Glu Val Lys Lys Glu Asn Gly Asp Lys Lys 
    210                 215                 220                 


Ile Val Pro Lys Lys Lys Lys Pro Leu Lys Leu Gly Pro Ile Lys Lys 
225                 230                 235                 240 


Lys Asp Leu Lys Lys Leu Val Leu Tyr Leu Lys Asn Gly Ala Asp Cys 
                245                 250                 255     


Pro Cys His Gln Leu Asp Asn Leu Ser His His Phe Leu Ile Met Gly 
            260                 265                 270         


Arg Lys Val Lys Ser Gln Tyr Leu Leu Thr Ala Ile His Lys Trp Asp 
        275                 280                 285             


Lys Lys Asn Lys Glu Phe Lys Asn Phe Met Lys Lys Met Lys Asn His 
    290                 295                 300                 


Glu Cys Pro Thr Phe Gln Ser Val Phe Lys 
305                 310                 


<210>  3785
<211>  215
<212>  PRT
<213>  homo sapiens

<400>  3785

Met Ala Asp Leu His Arg Gln Leu Gln Glu Tyr Leu Ala Gln Gly Lys 
1               5                   10                  15      


Ala Gly Gly Pro Ala Ala Ala Glu Pro Leu Leu Ala Ala Glu Lys Ala 
            20                  25                  30          


Glu Glu Pro Gly Asp Arg Pro Ala Glu Glu Trp Leu Gly Arg Ala Gly 
        35                  40                  45              


Leu Arg Trp Thr Trp Ala Arg Ser Pro Ala Glu Ser Ala Ala Ala Gly 
    50                  55                  60                  


Leu Thr Cys Leu Pro Ser Val Thr Arg Gly Gln Arg Leu Ala Ala Gly 
65                  70                  75                  80  


Gly Gly Cys Leu Leu Leu Ala Ala Leu Cys Phe Gly Leu Ala Ala Leu 
                85                  90                  95      


Tyr Ala Pro Val Leu Leu Leu Arg Ala Arg Lys Phe Ala Leu Leu Trp 
            100                 105                 110         


Ser Leu Gly Ser Ala Leu Ala Leu Ala Gly Ser Ala Leu Leu Arg Gly 
        115                 120                 125             


Gly Ala Ala Cys Gly Arg Leu Leu Arg Cys Glu Glu Ala Pro Ser Arg 
    130                 135                 140                 


Pro Ala Leu Leu Tyr Met Ala Ala Leu Gly Ala Thr Leu Phe Ala Ala 
145                 150                 155                 160 


Leu Gly Leu Arg Ser Thr Leu Leu Thr Val Leu Gly Ala Gly Ala Gln 
                165                 170                 175     


Val Ala Ala Leu Leu Ala Ala Leu Val Gly Leu Leu Pro Trp Gly Gly 
            180                 185                 190         


Gly Thr Ala Leu Arg Leu Ala Leu Gly Arg Leu Gly Arg Gly Ala Gly 
        195                 200                 205             


Leu Ala Lys Val Leu Pro Val 
    210                 215 


<210>  3786
<211>  1406
<212>  PRT
<213>  homo sapiens

<400>  3786

Met His Gln Thr Leu Cys Leu Asn Pro Glu Ser Leu Lys Met Ser Ala 
1               5                   10                  15      


Cys Ser Asp Phe Val Glu His Ile Trp Lys Pro Gly Ser Cys Lys Asn 
            20                  25                  30          


Cys Phe Cys Leu Arg Ser Asp His Gln Leu Val Ala Gly Pro Pro Gln 
        35                  40                  45              


Pro Arg Ala Gly Ser Leu Pro Pro Pro Pro Arg Leu Pro Pro Arg Pro 
    50                  55                  60                  


Glu Asn Cys Arg Leu Glu Asp Glu Gly Val Asn Ser Ser Pro Tyr Ser 
65                  70                  75                  80  


Lys Pro Thr Ile Ala Val Lys Pro Thr Met Met Ser Ser Glu Ala Ser 
                85                  90                  95      


Asp Val Trp Thr Glu Ala Asn Leu Ser Ala Glu Val Ser Gln Val Ile 
            100                 105                 110         


Trp Arg Arg Ala Pro Gly Lys Leu Pro Leu Pro Lys Gln Glu Asp Ala 
        115                 120                 125             


Pro Val Val Tyr Leu Gly Ser Phe Arg Gly Val Gln Lys Pro Ala Gly 
    130                 135                 140                 


Pro Ser Thr Ser Pro Asp Gly Asn Ser Arg Cys Pro Pro Ala Tyr Thr 
145                 150                 155                 160 


Met Val Gly Leu His Asn Leu Glu Pro Arg Gly Glu Arg Asn Ile Ala 
                165                 170                 175     


Phe His Pro Val Ser Phe Pro Glu Glu Lys Ala Val His Lys Glu Lys 
            180                 185                 190         


Pro Ser Phe Pro Tyr Gln Asp Arg Pro Ser Thr Gln Glu Ser Phe Arg 
        195                 200                 205             


Gln Lys Leu Ala Ala Phe Ala Gly Thr Thr Ser Gly Cys His Gln Gly 
    210                 215                 220                 


Pro Gly Pro Leu Arg Glu Ser Leu Pro Ser Glu Asp Asp Ser Asp Gln 
225                 230                 235                 240 


Arg Cys Ser Pro Ser Gly Asp Ser Glu Gly Gly Glu Tyr Cys Ser Ile 
                245                 250                 255     


Leu Asp Cys Cys Pro Gly Ser Pro Val Ala Lys Ala Ala Ser Gln Thr 
            260                 265                 270         


Ala Gly Ser Arg Gly Arg His Gly Gly Arg Asp Cys Ser Pro Thr Cys 
        275                 280                 285             


Trp Glu Gln Gly Lys Cys Ser Gly Pro Ala Glu Gln Glu Lys Arg Gly 
    290                 295                 300                 


Pro Ser Phe Pro Lys Glu Cys Cys Ser Gln Gly Pro Thr Ala His Pro 
305                 310                 315                 320 


Ser Cys Leu Gly Pro Lys Lys Leu Ser Leu Thr Ser Glu Ala Ala Ile 
                325                 330                 335     


Ser Ser Asp Gly Leu Ser Cys Gly Ser Gly Ser Gly Ser Gly Ser Gly 
            340                 345                 350         


Ala Ser Ser Pro Phe Val Pro His Leu Glu Ser Asp Tyr Cys Ser Leu 
        355                 360                 365             


Met Lys Glu Pro Ala Pro Glu Lys Gln Gln Asp Pro Gly Cys Pro Gly 
    370                 375                 380                 


Val Thr Pro Ser Arg Cys Leu Gly Leu Thr Gly Glu Pro Gln Pro Pro 
385                 390                 395                 400 


Ala His Pro Arg Glu Ala Thr Gln Pro Glu Pro Ile Tyr Ala Glu Ser 
                405                 410                 415     


Thr Lys Arg Lys Lys Ala Ala Pro Val Pro Ser Lys Ser Gln Ala Lys 
            420                 425                 430         


Ile Glu His Ala Ala Ala Ala Gln Gly Gln Gly Gln Val Cys Thr Gly 
        435                 440                 445             


Asn Ala Trp Ala Gln Lys Ala Ala Ser Gly Trp Gly Arg Asp Ser Pro 
    450                 455                 460                 


Asp Pro Thr Pro Gln Val Ser Ala Thr Ile Thr Val Met Ala Ala His 
465                 470                 475                 480 


Pro Glu Glu Asp His Arg Thr Ile Tyr Leu Ser Ser Pro Asp Ser Ala 
                485                 490                 495     


Val Gly Val Gln Trp Pro Arg Gly Pro Val Ser Gln Asn Ser Glu Val 
            500                 505                 510         


Gly Glu Glu Glu Thr Ser Ala Gly Gln Gly Leu Ser Ser Arg Glu Ser 
        515                 520                 525             


His Ala His Ser Ala Ser Glu Ser Lys Pro Lys Glu Arg Pro Ala Ile 
    530                 535                 540                 


Pro Pro Lys Leu Ser Lys Ser Ser Pro Val Gly Ser Pro Val Ser Pro 
545                 550                 555                 560 


Ser Ala Gly Gly Pro Pro Val Ser Pro Leu Ala Asp Leu Ser Asp Gly 
                565                 570                 575     


Ser Ser Gly Gly Ser Ser Ile Gly Pro Gln Pro Pro Ser Gln Gly Pro 
            580                 585                 590         


Ala Asp Pro Ala Pro Ser Cys Arg Thr Asn Gly Val Ala Ile Ser Asp 
        595                 600                 605             


Pro Ser Arg Cys Pro Gln Pro Ala Ala Ser Ser Ala Ser Glu Gln Arg 
    610                 615                 620                 


Arg Pro Arg Phe Gln Ala Gly Thr Trp Ser Arg Gln Cys Arg Ile Glu 
625                 630                 635                 640 


Glu Glu Glu Glu Val Glu Gln Glu Leu Leu Ser His Ser Trp Gly Arg 
                645                 650                 655     


Glu Thr Lys Asn Gly Pro Thr Asp His Ser Asn Ser Thr Thr Trp His 
            660                 665                 670         


Arg Leu His Pro Thr Asp Gly Ser Ser Gly Gln Asn Ser Lys Val Gly 
        675                 680                 685             


Thr Gly Met Ser Lys Ser Ala Ser Phe Ala Phe Glu Phe Pro Lys Asp 
    690                 695                 700                 


Arg Ser Gly Ile Glu Thr Phe Ser Pro Pro Pro Pro Pro Pro Lys Ser 
705                 710                 715                 720 


Arg His Leu Leu Lys Met Asn Lys Ser Ser Ser Asp Leu Glu Lys Val 
                725                 730                 735     


Ser Gln Gly Ser Ala Glu Ser Leu Ser Pro Ser Phe Arg Gly Val His 
            740                 745                 750         


Val Ser Phe Thr Thr Gly Ser Thr Asp Ser Leu Ala Ser Asp Ser Arg 
        755                 760                 765             


Thr Cys Ser Asp Gly Gly Pro Ser Ser Glu Leu Ala His Ser Pro Thr 
    770                 775                 780                 


Asn Ser Gly Lys Lys Leu Phe Ala Pro Val Pro Phe Pro Ser Gly Ser 
785                 790                 795                 800 


Thr Glu Asp Val Ser Pro Ser Gly Pro Gln Gln Pro Pro Pro Leu Pro 
                805                 810                 815     


Gln Lys Lys Ile Val Ser Arg Ala Ala Ser Ser Pro Asp Gly Phe Phe 
            820                 825                 830         


Trp Thr Gln Gly Ser Pro Lys Pro Gly Thr Ala Ser Pro Lys Leu Asn 
        835                 840                 845             


Leu Ser His Ser Glu Thr Asn Val His Asp Glu Ser His Phe Ser Tyr 
    850                 855                 860                 


Ser Leu Ser Pro Gly Asn Arg His His Pro Val Phe Ser Ser Ser Asp 
865                 870                 875                 880 


Pro Leu Glu Lys Ala Phe Lys Gly Ser Gly His Trp Leu Pro Ala Ala 
                885                 890                 895     


Gly Leu Ala Gly Asn Arg Gly Gly Cys Gly Ser Pro Gly Leu Gln Cys 
            900                 905                 910         


Lys Gly Ala Pro Ser Ala Ser Ser Ser Gln Leu Ser Val Ser Ser Gln 
        915                 920                 925             


Ala Ser Thr Gly Ser Thr Gln Leu Gln Leu His Gly Leu Leu Ser Asn 
    930                 935                 940                 


Ile Ser Ser Lys Glu Gly Thr Tyr Ala Lys Leu Gly Gly Leu Tyr Thr 
945                 950                 955                 960 


Gln Ser Leu Ala Arg Leu Val Ala Lys Cys Glu Asp Leu Phe Met Gly 
                965                 970                 975     


Gly Gln Lys Lys Glu Leu His Phe Asn Glu Asn Asn Trp Ser Leu Phe 
            980                 985                 990         


Lys Leu Thr Cys Asn Lys Pro Cys  Cys Asp Ser Gly Asp  Ala Ile Tyr 
        995                 1000                 1005             


Tyr Cys  Ala Thr Cys Ser Glu  Asp Pro Gly Ser Thr  Tyr Ala Val 
    1010                 1015                 1020             


Lys Ile  Cys Lys Ala Pro Glu  Pro Lys Thr Val Ser  Tyr Cys Ser 
    1025                 1030                 1035             


Pro Ser  Val Pro Val His Phe  Asn Ile Gln Gln Asp  Cys Gly His 
    1040                 1045                 1050             


Phe Val  Ala Ser Val Pro Ser  Ser Met Leu Ser Ser  Pro Asp Ala 
    1055                 1060                 1065             


Pro Lys  Asp Pro Val Pro Ala  Leu Pro Thr His Pro  Pro Ala Gln 
    1070                 1075                 1080             


Glu Gln  Asp Cys Val Val Val  Ile Thr Arg Glu Val  Pro His Gln 
    1085                 1090                 1095             


Thr Ala  Ser Asp Phe Val Arg  Asp Ser Ala Ala Ser  His Gln Ala 
    1100                 1105                 1110             


Glu Pro  Glu Ala Tyr Glu Arg  Arg Val Cys Phe Leu  Leu Leu Gln 
    1115                 1120                 1125             


Leu Cys  Asn Gly Leu Glu His  Leu Lys Glu His Gly  Ile Ile His 
    1130                 1135                 1140             


Arg Asp  Leu Cys Leu Glu Asn  Leu Leu Leu Val His  Cys Thr Leu 
    1145                 1150                 1155             


Gln Ala  Gly Pro Gly Pro Ala  Pro Ala Pro Ala Pro  Ala Pro Ala 
    1160                 1165                 1170             


Pro Ala  Ala Ala Ala Pro Pro  Cys Ser Ser Ala Ala  Pro Pro Ala 
    1175                 1180                 1185             


Gly Gly  Thr Leu Ser Pro Ala  Ala Gly Pro Ala Ser  Pro Glu Gly 
    1190                 1195                 1200             


Pro Arg  Glu Lys Gln Leu Pro  Arg Leu Ile Ile Ser  Asn Phe Leu 
    1205                 1210                 1215             


Lys Ala  Lys Gln Lys Pro Gly  Gly Thr Pro Asn Leu  Gln Gln Lys 
    1220                 1225                 1230             


Lys Ser  Gln Ala Arg Leu Ala  Pro Glu Ile Val Ser  Ala Ser Gln 
    1235                 1240                 1245             


Tyr Arg  Lys Phe Asp Glu Phe  Gln Thr Gly Ile Leu  Ile Tyr Glu 
    1250                 1255                 1260             


Leu Leu  His Gln Pro Asn Pro  Phe Glu Val Arg Ala  Gln Leu Arg 
    1265                 1270                 1275             


Glu Arg  Asp Tyr Arg Gln Glu  Asp Leu Pro Pro Leu  Pro Ala Leu 
    1280                 1285                 1290             


Ser Leu  Tyr Ser Pro Gly Leu  Gln Gln Leu Ala His  Leu Leu Leu 
    1295                 1300                 1305             


Glu Ala  Asp Pro Ile Lys Arg  Ile Arg Ile Gly Glu  Ala Lys Arg 
    1310                 1315                 1320             


Val Leu  Gln Cys Leu Leu Trp  Gly Pro Arg Arg Glu  Leu Val Gln 
    1325                 1330                 1335             


Gln Pro  Gly Thr Ser Glu Glu  Ala Leu Cys Gly Thr  Leu His Asn 
    1340                 1345                 1350             


Trp Ile  Asp Met Lys Arg Ala  Leu Met Met Met Lys  Phe Ala Glu 
    1355                 1360                 1365             


Lys Ala  Val Asp Arg Arg Arg  Gly Val Glu Leu Glu  Asp Trp Leu 
    1370                 1375                 1380             


Cys Cys  Gln Tyr Leu Ala Ser  Ala Glu Pro Gly Ala  Leu Leu Gln 
    1385                 1390                 1395             


Ser Leu  Lys Leu Leu Gln Leu  Leu 
    1400                 1405     


<210>  3787
<211>  760
<212>  PRT
<213>  homo sapiens

<400>  3787

Met Ser Thr Val Glu Glu Asp Ser Asp Thr Val Thr Val Glu Thr Val 
1               5                   10                  15      


Asn Ser Val Thr Leu Thr Gln Asp Thr Glu Gly Asn Leu Ile Leu His 
            20                  25                  30          


Cys Pro Gln Asn Glu Ala Asp Glu Ile Asp Ser Glu Asp Ser Ile Glu 
        35                  40                  45              


Pro Pro His Lys Arg Leu Cys Leu Ser Ser Glu Asp Asp Gln Ser Ile 
    50                  55                  60                  


Asp Asp Ser Thr Pro Cys Ile Ser Val Val Ala Leu Pro Leu Ser Glu 
65                  70                  75                  80  


Asn Asp Gln Ser Phe Glu Val Thr Met Thr Ala Thr Thr Glu Val Ala 
                85                  90                  95      


Asp Asp Glu Val Thr Glu Gly Thr Val Thr Gln Ile Gln Ile Leu Gln 
            100                 105                 110         


Asn Glu Gln Leu Asp Glu Ile Ser Pro Leu Gly Asn Glu Glu Val Ser 
        115                 120                 125             


Ala Val Ser Gln Ala Trp Phe Thr Thr Lys Glu Asp Lys Asp Ser Leu 
    130                 135                 140                 


Thr Asn Lys Gly His Lys Trp Lys Gln Gly Met Trp Ser Lys Glu Glu 
145                 150                 155                 160 


Ile Asp Ile Leu Met Asn Asn Ile Glu Arg Tyr Leu Lys Ala Arg Gly 
                165                 170                 175     


Ile Lys Asp Ala Thr Glu Ile Ile Phe Glu Met Ser Lys Asp Glu Arg 
            180                 185                 190         


Lys Asp Phe Tyr Arg Thr Ile Ala Trp Gly Leu Asn Arg Pro Leu Phe 
        195                 200                 205             


Ala Val Tyr Arg Arg Val Leu Arg Met Tyr Asp Asp Arg Asn His Val 
    210                 215                 220                 


Gly Lys Tyr Thr Pro Glu Glu Ile Glu Lys Leu Lys Glu Leu Arg Ile 
225                 230                 235                 240 


Lys His Gly Asn Asp Trp Ala Thr Ile Gly Ala Ala Leu Gly Arg Ser 
                245                 250                 255     


Ala Ser Ser Val Lys Asp Arg Cys Arg Leu Met Lys Asp Thr Cys Asn 
            260                 265                 270         


Thr Gly Lys Trp Thr Glu Glu Glu Glu Lys Arg Leu Ala Glu Val Val 
        275                 280                 285             


His Glu Leu Thr Ser Thr Glu Pro Gly Asp Ile Val Thr Gln Gly Val 
    290                 295                 300                 


Ser Trp Ala Ala Val Ala Glu Arg Val Gly Thr Arg Ser Glu Lys Gln 
305                 310                 315                 320 


Cys Arg Ser Lys Trp Leu Asn Tyr Leu Asn Trp Lys Gln Ser Gly Gly 
                325                 330                 335     


Thr Glu Trp Thr Lys Glu Asp Glu Ile Asn Leu Ile Leu Arg Ile Ala 
            340                 345                 350         


Glu Leu Asp Val Ala Asp Glu Asn Asp Ile Asn Trp Asp Leu Leu Ala 
        355                 360                 365             


Glu Gly Trp Ser Ser Val Arg Ser Pro Gln Trp Leu Arg Ser Lys Trp 
    370                 375                 380                 


Trp Thr Ile Lys Arg Gln Ile Ala Asn His Lys Asp Val Ser Phe Pro 
385                 390                 395                 400 


Val Leu Ile Lys Gly Leu Lys Gln Leu His Glu Asn Gln Lys Asn Asn 
                405                 410                 415     


Pro Thr Leu Leu Glu Asn Lys Ser Gly Ser Gly Val Pro Asn Ser Asn 
            420                 425                 430         


Thr Asn Ser Ser Val Gln His Val Gln Ile Arg Val Ala Arg Leu Glu 
        435                 440                 445             


Asp Asn Thr Ala Ile Ser Ser Ser Pro Met Ala Ala Leu Gln Ile Pro 
    450                 455                 460                 


Val Gln Ile Thr His Val Ser Ser Ala Asp Ser Pro Ala Thr Val Asp 
465                 470                 475                 480 


Ser Glu Thr Ile Thr Leu Asn Ser Gly Thr Leu Gln Thr Phe Glu Ile 
                485                 490                 495     


Leu Pro Ser Phe His Leu Gln Pro Thr Gly Thr Pro Gly Thr Tyr Leu 
            500                 505                 510         


Leu Gln Thr Ser Ser Ser Gln Gly Leu Pro Leu Thr Leu Thr Ala Ser 
        515                 520                 525             


Pro Thr Val Thr Leu Thr Ala Ala Ala Pro Ala Ser Pro Glu Gln Ile 
    530                 535                 540                 


Ile Val His Ala Leu Ser Pro Glu His Leu Leu Asn Thr Ser Asp Asn 
545                 550                 555                 560 


Val Thr Val Gln Cys His Thr Pro Arg Val Ile Ile Gln Thr Val Ala 
                565                 570                 575     


Thr Glu Asp Ile Thr Ser Ser Ile Ser Gln Ala Glu Leu Thr Val Asp 
            580                 585                 590         


Ser Asp Ile Gln Ser Ser Asp Phe Pro Glu Pro Pro Asp Ala Leu Glu 
        595                 600                 605             


Ala Asp Thr Phe Pro Asp Glu Ile His His Pro Lys Met Thr Val Glu 
    610                 615                 620                 


Pro Ser Phe Asn Asp Ala His Val Ser Lys Phe Ser Asp Gln Asn Ser 
625                 630                 635                 640 


Thr Glu Leu Met Asn Ser Val Met Val Arg Thr Glu Glu Glu Ile Ser 
                645                 650                 655     


Asp Thr Asp Leu Lys Gln Glu Glu Ser Pro Ser Asp Leu Ala Ser Ala 
            660                 665                 670         


Tyr Val Thr Glu Gly Leu Glu Ser Pro Thr Ile Glu Glu Gln Val Asp 
        675                 680                 685             


Gln Thr Ile Asp Asp Glu Thr Ile Leu Ile Val Pro Ser Pro His Gly 
    690                 695                 700                 


Phe Ile Gln Ala Ser Asp Val Ile Asp Thr Glu Ser Val Leu Pro Leu 
705                 710                 715                 720 


Thr Thr Leu Thr Asp Pro Ile Leu Gln His His Gln Glu Glu Ser Asn 
                725                 730                 735     


Ile Ile Gly Ser Ser Leu Gly Ser Pro Val Ser Glu Asp Ser Lys Asp 
            740                 745                 750         


Val Glu Asp Leu Val Asn Cys His 
        755                 760 


<210>  3788
<211>  504
<212>  PRT
<213>  homo sapiens

<400>  3788

Met Glu Ala Ala Ala Gln Phe Phe Val Glu Ser Pro Asp Val Val Tyr 
1               5                   10                  15      


Gly Pro Glu Ala Ile Glu Ala Gln Tyr Glu Tyr Arg Thr Thr Arg Val 
            20                  25                  30          


Ser Arg Glu Gly Gly Val Leu Lys Glu Ala Asn Tyr Tyr Gly Ser Leu 
        35                  40                  45              


Thr Gln Ala Gly Thr Val Ser Leu Gly Leu Asp Ala Glu Gly Gln Glu 
    50                  55                  60                  


Val Phe Val Pro Phe Ser Ala Val Leu Pro Met Val Ala Pro Asn Asp 
65                  70                  75                  80  


Leu Val Phe Asp Gly Trp Asp Ile Ser Ser Leu Asn Leu Ala Glu Ala 
                85                  90                  95      


Met Arg Arg Ala Lys Val Leu Asp Trp Gly Leu Gln Glu Gln Leu Trp 
            100                 105                 110         


Pro His Met Glu Ala Leu Arg Pro Arg Pro Ser Val Tyr Ile Pro Glu 
        115                 120                 125             


Phe Ile Ala Ala Asn Gln Ser Ala Arg Ala Asp Asn Leu Ile Pro Gly 
    130                 135                 140                 


Ser Arg Ala Gln Gln Leu Glu Gln Ile Arg Arg Asp Ile Arg Asp Phe 
145                 150                 155                 160 


Arg Ser Ser Ala Gly Leu Asp Lys Val Ile Val Leu Trp Thr Ala Asn 
                165                 170                 175     


Thr Glu Arg Phe Cys Glu Val Ile Pro Gly Leu Asn Asp Thr Ala Glu 
            180                 185                 190         


Asn Leu Leu Arg Thr Ile Glu Leu Gly Leu Glu Val Ser Pro Ser Thr 
        195                 200                 205             


Leu Phe Ala Val Ala Ser Ile Leu Glu Gly Cys Ala Phe Leu Asn Gly 
    210                 215                 220                 


Ser Pro Gln Asn Thr Leu Val Pro Gly Ala Leu Glu Leu Ala Trp Gln 
225                 230                 235                 240 


His Arg Val Phe Val Gly Gly Asp Asp Phe Lys Ser Gly Gln Thr Lys 
                245                 250                 255     


Val Lys Ser Val Leu Val Asp Phe Leu Ile Gly Ser Gly Leu Lys Thr 
            260                 265                 270         


Met Ser Ile Val Ser Tyr Asn His Leu Gly Asn Asn Asp Gly Glu Asn 
        275                 280                 285             


Leu Ser Ala Pro Leu Gln Phe Arg Ser Lys Glu Val Ser Lys Ser Asn 
    290                 295                 300                 


Val Val Asp Asp Met Val Gln Ser Asn Pro Val Leu Tyr Thr Pro Gly 
305                 310                 315                 320 


Glu Glu Pro Asp His Cys Val Val Ile Lys Tyr Val Pro Tyr Val Gly 
                325                 330                 335     


Asp Ser Lys Arg Ala Leu Asp Glu Tyr Thr Ser Glu Leu Met Leu Gly 
            340                 345                 350         


Gly Thr Asn Thr Leu Val Leu His Asn Thr Cys Glu Asp Ser Leu Leu 
        355                 360                 365             


Ala Ala Pro Ile Met Leu Asp Leu Ala Leu Leu Thr Glu Leu Cys Gln 
    370                 375                 380                 


Arg Val Ser Phe Cys Thr Asp Met Asp Pro Glu Pro Gln Thr Phe His 
385                 390                 395                 400 


Pro Val Leu Ser Leu Leu Ser Phe Leu Phe Lys Ala Pro Leu Val Pro 
                405                 410                 415     


Pro Gly Ser Pro Val Val Asn Ala Leu Phe Arg Gln Arg Ser Cys Ile 
            420                 425                 430         


Glu Asn Ile Leu Arg Ala Cys Val Gly Leu Pro Pro Gln Asn His Met 
        435                 440                 445             


Leu Leu Glu His Lys Met Glu Arg Pro Gly Pro Ser Leu Lys Arg Val 
    450                 455                 460                 


Gly Pro Val Ala Ala Thr Tyr Pro Met Leu Asn Lys Lys Gly Pro Val 
465                 470                 475                 480 


Pro Ala Ala Thr Asn Gly Cys Thr Gly Asp Ala Asn Gly His Leu Gln 
                485                 490                 495     


Glu Glu Pro Pro Met Pro Thr Thr 
            500                 


<210>  3789
<211>  1972
<212>  PRT
<213>  homo sapiens

<400>  3789

Met Gly Asp Asp Ser Glu Trp Leu Lys Leu Pro Val Asp Gln Lys Cys 
1               5                   10                  15      


Glu His Lys Leu Trp Lys Ala Arg Leu Ser Gly Tyr Glu Glu Ala Leu 
            20                  25                  30          


Lys Ile Phe Gln Lys Ile Lys Asp Glu Lys Ser Pro Glu Trp Ser Lys 
        35                  40                  45              


Phe Leu Gly Leu Ile Lys Lys Phe Val Thr Asp Ser Asn Ala Val Val 
    50                  55                  60                  


Gln Leu Lys Gly Leu Glu Ala Ala Leu Val Tyr Val Glu Asn Ala His 
65                  70                  75                  80  


Val Ala Gly Lys Thr Thr Gly Glu Val Val Ser Gly Val Val Ser Lys 
                85                  90                  95      


Val Phe Asn Gln Pro Lys Ala Lys Ala Lys Glu Leu Gly Ile Glu Ile 
            100                 105                 110         


Cys Leu Met Tyr Ile Glu Ile Glu Lys Gly Glu Ala Val Gln Glu Glu 
        115                 120                 125             


Leu Leu Lys Gly Leu Asp Asn Lys Asn Pro Lys Ile Ile Val Ala Cys 
    130                 135                 140                 


Ile Glu Thr Leu Arg Lys Ala Leu Ser Glu Phe Gly Ser Lys Ile Ile 
145                 150                 155                 160 


Leu Leu Lys Pro Ile Ile Lys Val Leu Pro Lys Leu Phe Glu Ser Arg 
                165                 170                 175     


Glu Lys Ala Val Arg Asp Glu Ala Lys Leu Ile Ala Val Glu Ile Tyr 
            180                 185                 190         


Arg Trp Ile Arg Asp Ala Leu Arg Pro Pro Leu Gln Asn Ile Asn Ser 
        195                 200                 205             


Val Gln Leu Lys Glu Leu Glu Glu Glu Trp Val Lys Leu Pro Thr Ser 
    210                 215                 220                 


Ala Pro Arg Pro Thr Arg Phe Leu Arg Ser Gln Gln Glu Leu Glu Ala 
225                 230                 235                 240 


Lys Leu Glu Gln Gln Gln Ser Ala Gly Gly Asp Ala Glu Gly Gly Gly 
                245                 250                 255     


Asp Asp Gly Asp Glu Val Pro Gln Ile Asp Ala Tyr Glu Leu Leu Glu 
            260                 265                 270         


Ala Val Glu Ile Leu Ser Lys Leu Pro Lys Asp Phe Tyr Asp Lys Ile 
        275                 280                 285             


Glu Ala Lys Lys Trp Gln Glu Arg Lys Glu Ala Leu Glu Ser Val Glu 
    290                 295                 300                 


Val Leu Ile Lys Asn Pro Lys Leu Glu Ala Gly Asp Tyr Ala Asp Leu 
305                 310                 315                 320 


Val Lys Ala Leu Lys Lys Val Val Gly Lys Asp Thr Asn Val Met Leu 
                325                 330                 335     


Val Ala Leu Ala Ala Lys Cys Leu Thr Gly Leu Ala Val Gly Leu Arg 
            340                 345                 350         


Lys Lys Phe Gly Gln Tyr Ala Gly His Val Val Pro Thr Ile Leu Glu 
        355                 360                 365             


Lys Phe Lys Glu Lys Lys Pro Gln Val Val Gln Ala Leu Gln Glu Ala 
    370                 375                 380                 


Ile Asp Ala Ile Phe Leu Thr Thr Thr Leu Gln Asn Ile Ser Glu Asp 
385                 390                 395                 400 


Val Leu Ala Val Met Asp Asn Lys Asn Pro Thr Ile Lys Gln Gln Thr 
                405                 410                 415     


Ser Leu Phe Ile Ala Arg Ser Phe Arg His Cys Thr Ala Ser Thr Leu 
            420                 425                 430         


Pro Lys Ser Leu Leu Lys Pro Phe Cys Ala Ala Leu Leu Lys His Ile 
        435                 440                 445             


Asn Asp Ser Ala Pro Glu Val Arg Asp Ala Ala Phe Glu Ala Leu Gly 
    450                 455                 460                 


Thr Ala Leu Lys Val Val Gly Glu Lys Ala Val Asn Pro Phe Leu Ala 
465                 470                 475                 480 


Asp Val Asp Lys Leu Lys Leu Asp Lys Ile Lys Glu Cys Ser Glu Lys 
                485                 490                 495     


Val Glu Leu Ile His Gly Lys Lys Ala Gly Leu Ala Ala Asp Lys Lys 
            500                 505                 510         


Glu Phe Lys Pro Leu Pro Gly Arg Thr Ala Ala Ser Gly Ala Ala Gly 
        515                 520                 525             


Asp Lys Asp Thr Lys Asp Ile Ser Ala Pro Lys Pro Gly Pro Leu Lys 
    530                 535                 540                 


Lys Ala Pro Ala Ala Lys Ala Gly Gly Pro Pro Lys Lys Gly Lys Pro 
545                 550                 555                 560 


Ala Ala Pro Gly Gly Ala Gly Asn Thr Gly Thr Lys Asn Lys Lys Gly 
                565                 570                 575     


Leu Glu Thr Lys Glu Ile Val Glu Pro Glu Leu Ser Ile Glu Val Cys 
            580                 585                 590         


Glu Glu Lys Ala Ser Ala Val Leu Pro Pro Thr Cys Ile Gln Leu Leu 
        595                 600                 605             


Asp Ser Ser Asn Trp Lys Glu Arg Leu Ala Cys Met Glu Glu Phe Gln 
    610                 615                 620                 


Lys Ala Val Glu Leu Met Asp Arg Thr Glu Met Pro Cys Gln Ala Leu 
625                 630                 635                 640 


Val Arg Met Leu Ala Lys Lys Pro Gly Trp Lys Glu Thr Asn Phe Gln 
                645                 650                 655     


Val Met Gln Met Lys Leu His Ile Val Ala Leu Ile Ala Gln Lys Gly 
            660                 665                 670         


Asn Phe Ser Lys Thr Ser Ala Gln Val Val Leu Asp Gly Leu Val Asp 
        675                 680                 685             


Lys Ile Gly Asp Val Lys Cys Gly Asn Asn Ala Lys Glu Ala Met Thr 
    690                 695                 700                 


Ala Ile Ala Glu Ala Cys Met Leu Pro Trp Thr Ala Glu Gln Val Val 
705                 710                 715                 720 


Ser Met Ala Phe Ser Gln Lys Asn Pro Lys Asn Gln Ser Glu Thr Leu 
                725                 730                 735     


Asn Trp Leu Ser Asn Ala Ile Lys Glu Phe Gly Phe Ser Gly Leu Asn 
            740                 745                 750         


Val Lys Ala Phe Ile Ser Asn Val Lys Thr Ala Leu Ala Ala Thr Asn 
        755                 760                 765             


Pro Ala Val Arg Thr Ala Ala Ile Thr Leu Leu Gly Val Met Tyr Leu 
    770                 775                 780                 


Tyr Val Gly Pro Ser Leu Arg Met Phe Phe Glu Asp Glu Lys Pro Ala 
785                 790                 795                 800 


Leu Leu Ser Gln Ile Asp Ala Glu Phe Glu Lys Met Gln Gly Gln Ser 
                805                 810                 815     


Pro Pro Ala Pro Thr Arg Gly Ile Ser Lys His Ser Thr Ser Gly Thr 
            820                 825                 830         


Asp Glu Gly Glu Asp Gly Asp Glu Pro Asp Asp Gly Ser Asn Asp Val 
        835                 840                 845             


Val Asp Leu Leu Pro Arg Thr Glu Ile Ser Asp Lys Ile Thr Ser Glu 
    850                 855                 860                 


Leu Val Ser Lys Ile Gly Asp Lys Asn Trp Lys Ile Arg Lys Glu Gly 
865                 870                 875                 880 


Leu Asp Glu Val Ala Gly Ile Ile Asn Asp Ala Lys Phe Ile Gln Pro 
                885                 890                 895     


Asn Ile Gly Glu Leu Pro Thr Ala Leu Lys Gly Arg Leu Asn Asp Ser 
            900                 905                 910         


Asn Lys Ile Leu Val Gln Gln Thr Leu Asn Ile Leu Gln Gln Leu Ala 
        915                 920                 925             


Val Ala Met Gly Pro Asn Ile Lys Gln His Val Lys Asn Leu Gly Ile 
    930                 935                 940                 


Pro Ile Ile Thr Val Leu Gly Asp Ser Lys Asn Asn Val Arg Ala Ala 
945                 950                 955                 960 


Ala Leu Ala Thr Val Asn Ala Trp Ala Glu Gln Thr Gly Met Lys Glu 
                965                 970                 975     


Trp Leu Glu Gly Glu Asp Leu Ser Glu Glu Leu Lys Lys Glu Asn Pro 
            980                 985                 990         


Phe Leu Arg Gln Glu Leu Leu Gly  Trp Leu Ala Glu Lys  Leu Pro Thr 
        995                 1000                 1005             


Leu Arg  Ser Thr Pro Thr Asp  Leu Ile Leu Cys Val  Pro His Leu 
    1010                 1015                 1020             


Tyr Ser  Cys Leu Glu Asp Arg  Asn Gly Asp Val Arg  Lys Lys Ala 
    1025                 1030                 1035             


Gln Asp  Ala Leu Pro Phe Phe  Met Met His Leu Gly  Tyr Glu Lys 
    1040                 1045                 1050             


Met Ala  Lys Ala Thr Gly Lys  Leu Lys Pro Thr Ser  Lys Asp Gln 
    1055                 1060                 1065             


Val Leu  Ala Met Leu Glu Lys  Ala Lys Val Asn Met  Pro Ala Lys 
    1070                 1075                 1080             


Pro Ala  Pro Pro Thr Lys Ala  Thr Ser Lys Pro Met  Gly Gly Ser 
    1085                 1090                 1095             


Ala Pro  Ala Lys Phe Gln Pro  Ala Ser Ala Pro Ala  Glu Asp Cys 
    1100                 1105                 1110             


Ile Ser  Ser Ser Thr Glu Pro  Lys Pro Asp Pro Lys  Lys Ala Lys 
    1115                 1120                 1125             


Ala Pro  Gly Leu Ser Ser Lys  Ala Lys Ser Ala Gln  Gly Lys Lys 
    1130                 1135                 1140             


Met Pro  Ser Lys Thr Ser Leu  Lys Glu Asp Glu Asp  Lys Ser Gly 
    1145                 1150                 1155             


Pro Ile  Phe Ile Val Val Pro  Asn Gly Lys Glu Gln  Arg Met Lys 
    1160                 1165                 1170             


Asp Glu  Lys Gly Leu Lys Val  Leu Lys Trp Asn Phe  Thr Thr Pro 
    1175                 1180                 1185             


Arg Asp  Glu Tyr Ile Glu Gln  Leu Lys Thr Gln Met  Ser Ser Cys 
    1190                 1195                 1200             


Val Ala  Lys Trp Leu Gln Asp  Glu Met Phe His Ser  Asp Phe Gln 
    1205                 1210                 1215             


His His  Asn Lys Ala Leu Ala  Val Met Val Asp His  Leu Glu Ser 
    1220                 1225                 1230             


Glu Lys  Glu Gly Val Ile Gly  Cys Leu Asp Leu Ile  Leu Lys Trp 
    1235                 1240                 1245             


Leu Thr  Leu Arg Phe Phe Asp  Thr Asn Thr Ser Val  Leu Met Lys 
    1250                 1255                 1260             


Ala Leu  Glu Tyr Leu Lys Leu  Leu Phe Thr Leu Leu  Ser Glu Glu 
    1265                 1270                 1275             


Glu Tyr  His Leu Thr Glu Asn  Glu Ala Ser Ser Phe  Ile Pro Tyr 
    1280                 1285                 1290             


Leu Val  Val Lys Val Gly Glu  Pro Lys Asp Val Ile  Arg Lys Asp 
    1295                 1300                 1305             


Val Arg  Ala Ile Leu Asn Arg  Met Cys Leu Val Tyr  Pro Ala Ser 
    1310                 1315                 1320             


Lys Met  Phe Pro Phe Ile Met  Glu Gly Thr Lys Ser  Lys Asn Ser 
    1325                 1330                 1335             


Lys Gln  Arg Ala Glu Cys Leu  Glu Glu Leu Gly Cys  Leu Val Glu 
    1340                 1345                 1350             


Ser Tyr  Gly Met Asn Val Cys  Gln Pro Thr Pro Gly  Lys Ala Leu 
    1355                 1360                 1365             


Lys Glu  Ile Ala Val His Ile  Gly Asp Arg Asp Asn  Ala Val Arg 
    1370                 1375                 1380             


Asn Ala  Ala Leu Asn Thr Ile  Val Thr Val Tyr Asn  Val His Gly 
    1385                 1390                 1395             


Asp Gln  Val Phe Lys Leu Ile  Gly Asn Leu Ser Glu  Lys Asp Met 
    1400                 1405                 1410             


Ser Met  Leu Glu Glu Arg Ile  Lys Arg Ser Ala Lys  Arg Pro Ser 
    1415                 1420                 1425             


Ala Ala  Pro Ile Lys Gln Val  Glu Glu Lys Pro Gln  Arg Ala Gln 
    1430                 1435                 1440             


Asn Ile  Ser Ser Asn Ala Asn  Met Leu Arg Lys Gly  Pro Ala Glu 
    1445                 1450                 1455             


Asp Met  Ser Ser Lys Leu Asn  Gln Ala Arg Ser Met  Ser Gly His 
    1460                 1465                 1470             


Pro Glu  Ala Ala Gln Met Val  Arg Arg Glu Phe Gln  Leu Asp Leu 
    1475                 1480                 1485             


Asp Glu  Ile Glu Asn Asp Asn  Gly Thr Val Arg Cys  Glu Met Pro 
    1490                 1495                 1500             


Glu Leu  Val Gln His Lys Leu  Asp Asp Ile Phe Glu  Pro Val Leu 
    1505                 1510                 1515             


Ile Pro  Glu Pro Lys Ile Arg  Ala Val Ser Pro His  Phe Asp Asp 
    1520                 1525                 1530             


Met His  Ser Asn Thr Ala Ser  Thr Ile Asn Phe Ile  Ile Ser Gln 
    1535                 1540                 1545             


Val Ala  Ser Gly Asp Ile Asn  Thr Ser Ile Gln Ala  Leu Thr Gln 
    1550                 1555                 1560             


Leu Phe  Gln Ile Glu Ser Leu  Ala Arg Glu Ala Ser  Thr Gly Val 
    1565                 1570                 1575             


Leu Lys  Asp Leu Met His Gly  Leu Ile Thr Leu Met  Leu Asp Ser 
    1580                 1585                 1590             


Arg Ile  Glu Asp Leu Glu Glu  Gly Gln Gln Val Ile  Arg Ser Val 
    1595                 1600                 1605             


Asn Leu  Leu Val Val Lys Val  Leu Glu Lys Ser Asp  Gln Thr Asn 
    1610                 1615                 1620             


Ile Leu  Ser Ala Leu Leu Val  Leu Leu Gln Asp Ser  Leu Leu Ala 
    1625                 1630                 1635             


Thr Ala  Ser Ser Pro Lys Phe  Ser Glu Leu Val Met  Lys Cys Leu 
    1640                 1645                 1650             


Trp Arg  Met Val Arg Leu Leu  Pro Asp Thr Ile Asn  Ser Ile Asn 
    1655                 1660                 1665             


Leu Asp  Arg Ile Leu Leu Asp  Ile His Ile Phe Met  Lys Val Phe 
    1670                 1675                 1680             


Pro Lys  Glu Lys Leu Lys Gln  Cys Lys Ser Glu Phe  Pro Ile Arg 
    1685                 1690                 1695             


Thr Leu  Lys Thr Leu Leu His  Thr Leu Cys Lys Leu  Lys Gly Pro 
    1700                 1705                 1710             


Lys Ile  Leu Asp His Leu Thr  Met Ile Asp Asn Lys  Asn Glu Ser 
    1715                 1720                 1725             


Glu Leu  Glu Ala His Leu Cys  Arg Met Met Lys His  Ser Met Asp 
    1730                 1735                 1740             


Gln Thr  Gly Ser Lys Ser Asp  Lys Glu Thr Glu Lys  Gly Ala Ser 
    1745                 1750                 1755             


Arg Ile  Asp Glu Lys Ser Ser  Lys Ala Lys Val Asn  Asp Phe Leu 
    1760                 1765                 1770             


Ala Glu  Ile Phe Lys Lys Ile  Gly Ser Lys Glu Asn  Thr Lys Glu 
    1775                 1780                 1785             


Gly Leu  Ala Glu Leu Tyr Glu  Tyr Lys Lys Lys Tyr  Ser Asp Ala 
    1790                 1795                 1800             


Asp Ile  Glu Pro Phe Leu Lys  Asn Ser Ser Gln Phe  Phe Gln Ser 
    1805                 1810                 1815             


Tyr Val  Glu Arg Gly Leu Arg  Val Ile Glu Met Glu  Arg Glu Gly 
    1820                 1825                 1830             


Lys Gly  Arg Ile Ser Thr Ser  Thr Gly Ile Ser Pro  Gln Met Glu 
    1835                 1840                 1845             


Val Thr  Cys Val Pro Thr Pro  Thr Ser Thr Val Ser  Ser Ile Gly 
    1850                 1855                 1860             


Asn Thr  Asn Gly Glu Glu Val  Gly Pro Ser Val Tyr  Leu Glu Arg 
    1865                 1870                 1875             


Leu Lys  Ile Leu Arg Gln Arg  Cys Gly Leu Asp Asn  Thr Lys Gln 
    1880                 1885                 1890             


Asp Asp  Arg Pro Pro Leu Thr  Ser Leu Leu Ser Lys  Pro Ala Val 
    1895                 1900                 1905             


Pro Thr  Val Ala Ser Ser Thr  Asp Met Leu His Ser  Lys Leu Ser 
    1910                 1915                 1920             


Gln Leu  Arg Glu Ser Arg Glu  Gln His Gln His Ser  Asp Leu Asp 
    1925                 1930                 1935             


Ser Asn  Gln Thr His Ser Ser  Gly Thr Val Thr Ser  Ser Ser Ser 
    1940                 1945                 1950             


Thr Ala  Asn Ile Asp Asp Leu  Lys Lys Arg Leu Glu  Arg Ile Lys 
    1955                 1960                 1965             


Ser Ser  Arg Lys 
    1970         


<210>  3790
<211>  4655
<212>  PRT
<213>  homo sapiens

<400>  3790

Met Asp Arg Gly Pro Ala Ala Val Ala Cys Thr Leu Leu Leu Ala Leu 
1               5                   10                  15      


Val Ala Cys Leu Ala Pro Ala Ser Gly Gln Glu Cys Asp Ser Ala His 
            20                  25                  30          


Phe Arg Cys Gly Ser Gly His Cys Ile Pro Ala Asp Trp Arg Cys Asp 
        35                  40                  45              


Gly Thr Lys Asp Cys Ser Asp Asp Ala Asp Glu Ile Gly Cys Ala Val 
    50                  55                  60                  


Val Thr Cys Gln Gln Gly Tyr Phe Lys Cys Gln Ser Glu Gly Gln Cys 
65                  70                  75                  80  


Ile Pro Asn Ser Trp Val Cys Asp Gln Asp Gln Asp Cys Asp Asp Gly 
                85                  90                  95      


Ser Asp Glu Arg Gln Asp Cys Ser Gln Ser Thr Cys Ser Ser His Gln 
            100                 105                 110         


Ile Thr Cys Ser Asn Gly Gln Cys Ile Pro Ser Glu Tyr Arg Cys Asp 
        115                 120                 125             


His Val Arg Asp Cys Pro Asp Gly Ala Asp Glu Asn Asp Cys Gln Tyr 
    130                 135                 140                 


Pro Thr Cys Glu Gln Leu Thr Cys Asp Asn Gly Ala Cys Tyr Asn Thr 
145                 150                 155                 160 


Ser Gln Lys Cys Asp Trp Lys Val Asp Cys Arg Asp Ser Ser Asp Glu 
                165                 170                 175     


Ile Asn Cys Thr Glu Ile Cys Leu His Asn Glu Phe Ser Cys Gly Asn 
            180                 185                 190         


Gly Glu Cys Ile Pro Arg Ala Tyr Val Cys Asp His Asp Asn Asp Cys 
        195                 200                 205             


Gln Asp Gly Ser Asp Glu His Ala Cys Asn Tyr Pro Thr Cys Gly Gly 
    210                 215                 220                 


Tyr Gln Phe Thr Cys Pro Ser Gly Arg Cys Ile Tyr Gln Asn Trp Val 
225                 230                 235                 240 


Cys Asp Gly Glu Asp Asp Cys Lys Asp Asn Gly Asp Glu Asp Gly Cys 
                245                 250                 255     


Glu Ser Gly Pro His Asp Val His Lys Cys Ser Pro Arg Glu Trp Ser 
            260                 265                 270         


Cys Pro Glu Ser Gly Arg Cys Ile Ser Ile Tyr Lys Val Cys Asp Gly 
        275                 280                 285             


Ile Leu Asp Cys Pro Gly Arg Glu Asp Glu Asn Asn Thr Ser Thr Gly 
    290                 295                 300                 


Lys Tyr Cys Ser Met Thr Leu Cys Ser Ala Leu Asn Cys Gln Tyr Gln 
305                 310                 315                 320 


Cys His Glu Thr Pro Tyr Gly Gly Ala Cys Phe Cys Pro Pro Gly Tyr 
                325                 330                 335     


Ile Ile Asn His Asn Asp Ser Arg Thr Cys Val Glu Phe Asp Asp Cys 
            340                 345                 350         


Gln Ile Trp Gly Ile Cys Asp Gln Lys Cys Glu Ser Arg Pro Gly Arg 
        355                 360                 365             


His Leu Cys His Cys Glu Glu Gly Tyr Ile Leu Glu Arg Gly Gln Tyr 
    370                 375                 380                 


Cys Lys Ala Asn Asp Ser Phe Gly Glu Ala Ser Ile Ile Phe Ser Asn 
385                 390                 395                 400 


Gly Arg Asp Leu Leu Ile Gly Asp Ile His Gly Arg Ser Phe Arg Ile 
                405                 410                 415     


Leu Val Glu Ser Gln Asn Arg Gly Val Ala Val Gly Val Ala Phe His 
            420                 425                 430         


Tyr His Leu Gln Arg Val Phe Trp Thr Asp Thr Val Gln Asn Lys Val 
        435                 440                 445             


Phe Ser Val Asp Ile Asn Gly Leu Asn Ile Gln Glu Val Leu Asn Val 
    450                 455                 460                 


Ser Val Glu Thr Pro Glu Asn Leu Ala Val Asp Trp Val Asn Asn Lys 
465                 470                 475                 480 


Ile Tyr Leu Val Glu Thr Lys Val Asn Arg Ile Asp Met Val Asn Leu 
                485                 490                 495     


Asp Gly Ser Tyr Arg Val Thr Leu Ile Thr Glu Asn Leu Gly His Pro 
            500                 505                 510         


Arg Gly Ile Ala Val Asp Pro Thr Val Gly Tyr Leu Phe Phe Ser Asp 
        515                 520                 525             


Trp Glu Ser Leu Ser Gly Glu Pro Lys Leu Glu Arg Ala Phe Met Asp 
    530                 535                 540                 


Gly Ser Asn Arg Lys Asp Leu Val Lys Thr Lys Leu Gly Trp Pro Ala 
545                 550                 555                 560 


Gly Val Thr Leu Asp Met Ile Ser Lys Arg Val Tyr Trp Val Asp Ser 
                565                 570                 575     


Arg Phe Asp Tyr Ile Glu Thr Val Thr Tyr Asp Gly Ile Gln Arg Lys 
            580                 585                 590         


Thr Val Val His Gly Gly Ser Leu Ile Pro His Pro Phe Gly Val Ser 
        595                 600                 605             


Leu Phe Glu Gly Gln Val Phe Phe Thr Asp Trp Thr Lys Met Ala Val 
    610                 615                 620                 


Leu Lys Ala Asn Lys Phe Thr Glu Thr Asn Pro Gln Val Tyr Tyr Gln 
625                 630                 635                 640 


Ala Ser Leu Arg Pro Tyr Gly Val Thr Val Tyr His Ser Leu Arg Gln 
                645                 650                 655     


Pro Tyr Ala Thr Asn Pro Cys Lys Asp Asn Asn Gly Gly Cys Glu Gln 
            660                 665                 670         


Val Cys Val Leu Ser His Arg Thr Asp Asn Asp Gly Leu Gly Phe Arg 
        675                 680                 685             


Cys Lys Cys Thr Phe Gly Phe Gln Leu Asp Thr Asp Glu Arg His Cys 
    690                 695                 700                 


Ile Ala Val Gln Asn Phe Leu Ile Phe Ser Ser Gln Val Ala Ile Arg 
705                 710                 715                 720 


Gly Ile Pro Phe Thr Leu Ser Thr Gln Glu Asp Val Met Val Pro Val 
                725                 730                 735     


Ser Gly Asn Pro Ser Phe Phe Val Gly Ile Asp Phe Asp Ala Gln Asp 
            740                 745                 750         


Ser Thr Ile Phe Phe Ser Asp Met Ser Lys His Met Ile Phe Lys Gln 
        755                 760                 765             


Lys Ile Asp Gly Thr Gly Arg Glu Ile Leu Ala Ala Asn Arg Val Glu 
    770                 775                 780                 


Asn Val Glu Ser Leu Ala Phe Asp Trp Ile Ser Lys Asn Leu Tyr Trp 
785                 790                 795                 800 


Thr Asp Ser His Tyr Lys Ser Ile Ser Val Met Arg Leu Ala Asp Lys 
                805                 810                 815     


Thr Arg Arg Thr Val Val Gln Tyr Leu Asn Asn Pro Arg Ser Val Val 
            820                 825                 830         


Val His Pro Phe Ala Gly Tyr Leu Phe Phe Thr Asp Trp Phe Arg Pro 
        835                 840                 845             


Ala Lys Ile Met Arg Ala Trp Ser Asp Gly Ser His Leu Leu Pro Val 
    850                 855                 860                 


Ile Asn Thr Thr Leu Gly Trp Pro Asn Gly Leu Ala Ile Asp Trp Ala 
865                 870                 875                 880 


Ala Ser Arg Leu Tyr Trp Val Asp Ala Tyr Phe Asp Lys Ile Glu His 
                885                 890                 895     


Ser Thr Phe Asp Gly Leu Asp Arg Arg Arg Leu Gly His Ile Glu Gln 
            900                 905                 910         


Met Thr His Pro Phe Gly Leu Ala Ile Phe Gly Glu His Leu Phe Phe 
        915                 920                 925             


Thr Asp Trp Arg Leu Gly Ala Ile Ile Arg Val Arg Lys Ala Asp Gly 
    930                 935                 940                 


Gly Glu Met Thr Val Ile Arg Ser Gly Ile Ala Tyr Ile Leu His Leu 
945                 950                 955                 960 


Lys Ser Tyr Asp Val Asn Ile Gln Thr Gly Ser Asn Ala Cys Asn Gln 
                965                 970                 975     


Pro Thr His Pro Asn Gly Asp Cys Ser His Phe Cys Phe Pro Val Pro 
            980                 985                 990         


Asn Phe Gln Arg Val Cys Gly Cys  Pro Tyr Gly Met Arg  Leu Ala Ser 
        995                 1000                 1005             


Asn His  Leu Thr Cys Glu Gly  Asp Pro Thr Asn Glu  Pro Pro Thr 
    1010                 1015                 1020             


Glu Gln  Cys Gly Leu Phe Ser  Phe Pro Cys Lys Asn  Gly Arg Cys 
    1025                 1030                 1035             


Val Pro  Asn Tyr Tyr Leu Cys  Asp Gly Val Asp Asp  Cys His Asp 
    1040                 1045                 1050             


Asn Ser  Asp Glu Gln Leu Cys  Gly Thr Leu Asn Asn  Thr Cys Ser 
    1055                 1060                 1065             


Ser Ser  Ala Phe Thr Cys Gly  His Gly Glu Cys Ile  Pro Ala His 
    1070                 1075                 1080             


Trp Arg  Cys Asp Lys Arg Asn  Asp Cys Val Asp Gly  Ser Asp Glu 
    1085                 1090                 1095             


His Asn  Cys Pro Thr His Ala  Pro Ala Ser Cys Leu  Asp Thr Gln 
    1100                 1105                 1110             


Tyr Thr  Cys Asp Asn His Gln  Cys Ile Ser Lys Asn  Trp Val Cys 
    1115                 1120                 1125             


Asp Thr  Asp Asn Asp Cys Gly  Asp Gly Ser Asp Glu  Lys Asn Cys 
    1130                 1135                 1140             


Asn Ser  Thr Glu Thr Cys Gln  Pro Ser Gln Phe Asn  Cys Pro Asn 
    1145                 1150                 1155             


His Arg  Cys Ile Asp Leu Ser  Phe Val Cys Asp Gly  Asp Lys Asp 
    1160                 1165                 1170             


Cys Val  Asp Gly Ser Asp Glu  Val Gly Cys Val Leu  Asn Cys Thr 
    1175                 1180                 1185             


Ala Ser  Gln Phe Lys Cys Ala  Ser Gly Asp Lys Cys  Ile Gly Val 
    1190                 1195                 1200             


Thr Asn  Arg Cys Asp Gly Val  Phe Asp Cys Ser Asp  Asn Ser Asp 
    1205                 1210                 1215             


Glu Ala  Gly Cys Pro Thr Arg  Pro Pro Gly Met Cys  His Ser Asp 
    1220                 1225                 1230             


Glu Phe  Gln Cys Gln Glu Asp  Gly Ile Cys Ile Pro  Asn Phe Trp 
    1235                 1240                 1245             


Glu Cys  Asp Gly His Pro Asp  Cys Leu Tyr Gly Ser  Asp Glu His 
    1250                 1255                 1260             


Asn Ala  Cys Val Pro Lys Thr  Cys Pro Ser Ser Tyr  Phe His Cys 
    1265                 1270                 1275             


Asp Asn  Gly Asn Cys Ile His  Arg Ala Trp Leu Cys  Asp Arg Asp 
    1280                 1285                 1290             


Asn Asp  Cys Gly Asp Met Ser  Asp Glu Lys Asp Cys  Pro Thr Gln 
    1295                 1300                 1305             


Pro Phe  Arg Cys Pro Ser Trp  Gln Trp Gln Cys Leu  Gly His Asn 
    1310                 1315                 1320             


Ile Cys  Val Asn Leu Ser Val  Val Cys Asp Gly Ile  Phe Asp Cys 
    1325                 1330                 1335             


Pro Asn  Gly Thr Asp Glu Ser  Pro Leu Cys Asn Gly  Asn Ser Cys 
    1340                 1345                 1350             


Ser Asp  Phe Asn Gly Gly Cys  Thr His Glu Cys Val  Gln Glu Pro 
    1355                 1360                 1365             


Phe Gly  Ala Lys Cys Leu Cys  Pro Leu Gly Phe Leu  Leu Ala Asn 
    1370                 1375                 1380             


Asp Ser  Lys Thr Cys Glu Asp  Ile Asp Glu Cys Asp  Ile Leu Gly 
    1385                 1390                 1395             


Ser Cys  Ser Gln His Cys Tyr  Asn Met Arg Gly Ser  Phe Arg Cys 
    1400                 1405                 1410             


Ser Cys  Asp Thr Gly Tyr Met  Leu Glu Ser Asp Gly  Arg Thr Cys 
    1415                 1420                 1425             


Lys Val  Thr Ala Ser Glu Ser  Leu Leu Leu Leu Val  Ala Ser Gln 
    1430                 1435                 1440             


Asn Lys  Ile Ile Ala Asp Ser  Val Thr Ser Gln Val  His Asn Ile 
    1445                 1450                 1455             


Tyr Ser  Leu Val Glu Asn Gly  Ser Tyr Ile Val Ala  Val Asp Phe 
    1460                 1465                 1470             


Asp Ser  Ile Ser Gly Arg Ile  Phe Trp Ser Asp Ala  Thr Gln Gly 
    1475                 1480                 1485             


Lys Thr  Trp Ser Ala Phe Gln  Asn Gly Thr Asp Arg  Arg Val Val 
    1490                 1495                 1500             


Phe Asp  Ser Ser Ile Ile Leu  Thr Glu Thr Ile Ala  Ile Asp Trp 
    1505                 1510                 1515             


Val Gly  Arg Asn Leu Tyr Trp  Thr Asp Tyr Ala Leu  Glu Thr Ile 
    1520                 1525                 1530             


Glu Val  Ser Lys Ile Asp Gly  Ser His Arg Thr Val  Leu Ile Ser 
    1535                 1540                 1545             


Lys Asn  Leu Thr Asn Pro Arg  Gly Leu Ala Leu Asp  Pro Arg Met 
    1550                 1555                 1560             


Asn Glu  His Leu Leu Phe Trp  Ser Asp Trp Gly His  His Pro Arg 
    1565                 1570                 1575             


Ile Glu  Arg Ala Ser Met Asp  Gly Ser Met Arg Thr  Val Ile Val 
    1580                 1585                 1590             


Gln Asp  Lys Ile Phe Trp Pro  Cys Gly Leu Thr Ile  Asp Tyr Pro 
    1595                 1600                 1605             


Asn Arg  Leu Leu Tyr Phe Met  Asp Ser Tyr Leu Asp  Tyr Met Asp 
    1610                 1615                 1620             


Phe Cys  Asp Tyr Asn Gly His  His Arg Arg Gln Val  Ile Ala Ser 
    1625                 1630                 1635             


Asp Leu  Ile Ile Arg His Pro  Tyr Ala Leu Thr Leu  Phe Glu Asp 
    1640                 1645                 1650             


Ser Val  Tyr Trp Thr Asp Arg  Ala Thr Arg Arg Val  Met Arg Ala 
    1655                 1660                 1665             


Asn Lys  Trp His Gly Gly Asn  Gln Ser Val Val Met  Tyr Asn Ile 
    1670                 1675                 1680             


Gln Trp  Pro Leu Gly Ile Val  Ala Val His Pro Ser  Lys Gln Pro 
    1685                 1690                 1695             


Asn Ser  Val Asn Pro Cys Ala  Phe Ser Arg Cys Ser  His Leu Cys 
    1700                 1705                 1710             


Leu Leu  Ser Ser Gln Gly Pro  His Phe Tyr Ser Cys  Val Cys Pro 
    1715                 1720                 1725             


Ser Gly  Trp Ser Leu Ser Pro  Asp Leu Leu Asn Cys  Leu Arg Asp 
    1730                 1735                 1740             


Asp Gln  Pro Phe Leu Ile Thr  Val Arg Gln His Ile  Ile Phe Gly 
    1745                 1750                 1755             


Ile Ser  Leu Asn Pro Glu Val  Lys Ser Asn Asp Ala  Met Val Pro 
    1760                 1765                 1770             


Ile Ala  Gly Ile Gln Asn Gly  Leu Asp Val Glu Phe  Asp Asp Ala 
    1775                 1780                 1785             


Glu Gln  Tyr Ile Tyr Trp Val  Glu Asn Pro Gly Glu  Ile His Arg 
    1790                 1795                 1800             


Val Lys  Thr Asp Gly Thr Asn  Arg Thr Val Phe Ala  Ser Ile Ser 
    1805                 1810                 1815             


Met Val  Gly Pro Ser Met Asn  Leu Ala Leu Asp Trp  Ile Ser Arg 
    1820                 1825                 1830             


Asn Leu  Tyr Ser Thr Asn Pro  Arg Thr Gln Ser Ile  Glu Val Leu 
    1835                 1840                 1845             


Thr Leu  His Gly Asp Ile Arg  Tyr Arg Lys Thr Leu  Ile Ala Asn 
    1850                 1855                 1860             


Asp Gly  Thr Ala Leu Gly Val  Gly Phe Pro Ile Gly  Ile Thr Val 
    1865                 1870                 1875             


Asp Pro  Ala Arg Gly Lys Leu  Tyr Trp Ser Asp Gln  Gly Thr Asp 
    1880                 1885                 1890             


Ser Gly  Val Pro Ala Lys Ile  Ala Ser Ala Asn Met  Asp Gly Thr 
    1895                 1900                 1905             


Ser Val  Lys Thr Leu Phe Thr  Gly Asn Leu Glu His  Leu Glu Cys 
    1910                 1915                 1920             


Val Thr  Leu Asp Ile Glu Glu  Gln Lys Leu Tyr Trp  Ala Val Thr 
    1925                 1930                 1935             


Gly Arg  Gly Val Ile Glu Arg  Gly Asn Val Asp Gly  Thr Asp Arg 
    1940                 1945                 1950             


Met Ile  Leu Val His Gln Leu  Ser His Pro Trp Gly  Ile Ala Val 
    1955                 1960                 1965             


His Asp  Ser Phe Leu Tyr Tyr  Thr Asp Glu Gln Tyr  Glu Val Ile 
    1970                 1975                 1980             


Glu Arg  Val Asp Lys Ala Thr  Gly Ala Asn Lys Ile  Val Leu Arg 
    1985                 1990                 1995             


Asp Asn  Val Pro Asn Leu Arg  Gly Leu Gln Val Tyr  His Arg Arg 
    2000                 2005                 2010             


Asn Ala  Ala Glu Ser Ser Asn  Gly Cys Ser Asn Asn  Met Asn Ala 
    2015                 2020                 2025             


Cys Gln  Gln Ile Cys Leu Pro  Val Pro Gly Gly Leu  Phe Ser Cys 
    2030                 2035                 2040             


Ala Cys  Ala Thr Gly Phe Lys  Leu Asn Pro Asp Asn  Arg Ser Cys 
    2045                 2050                 2055             


Ser Pro  Tyr Asn Ser Phe Ile  Val Val Ser Met Leu  Ser Ala Ile 
    2060                 2065                 2070             


Arg Gly  Phe Ser Leu Glu Leu  Ser Asp His Ser Glu  Thr Met Val 
    2075                 2080                 2085             


Pro Val  Ala Gly Gln Gly Arg  Asn Ala Leu His Val  Asp Val Asp 
    2090                 2095                 2100             


Val Ser  Ser Gly Phe Ile Tyr  Trp Cys Asp Phe Ser  Ser Ser Val 
    2105                 2110                 2115             


Ala Ser  Asp Asn Ala Ile Arg  Arg Ile Lys Pro Asp  Gly Ser Ser 
    2120                 2125                 2130             


Leu Met  Asn Ile Val Thr His  Gly Ile Gly Glu Asn  Gly Val Arg 
    2135                 2140                 2145             


Gly Ile  Ala Val Asp Trp Val  Ala Gly Asn Leu Tyr  Phe Thr Asn 
    2150                 2155                 2160             


Ala Phe  Val Ser Glu Thr Leu  Ile Glu Val Leu Arg  Ile Asn Thr 
    2165                 2170                 2175             


Thr Tyr  Arg Arg Val Leu Leu  Lys Val Thr Val Asp  Met Pro Arg 
    2180                 2185                 2190             


His Ile  Val Val Asp Pro Lys  Asn Arg Tyr Leu Phe  Trp Ala Asp 
    2195                 2200                 2205             


Tyr Gly  Gln Arg Pro Lys Ile  Glu Arg Ser Phe Leu  Asp Cys Thr 
    2210                 2215                 2220             


Asn Arg  Thr Val Leu Val Ser  Glu Gly Ile Val Thr  Pro Arg Gly 
    2225                 2230                 2235             


Leu Ala  Val Asp Arg Ser Asp  Gly Tyr Val Tyr Trp  Val Asp Asp 
    2240                 2245                 2250             


Ser Leu  Asp Ile Ile Ala Arg  Ile Arg Ile Asn Gly  Glu Asn Ser 
    2255                 2260                 2265             


Glu Val  Ile Arg Tyr Gly Ser  Arg Tyr Pro Thr Pro  Tyr Gly Ile 
    2270                 2275                 2280             


Thr Val  Phe Glu Asn Ser Ile  Ile Trp Val Asp Arg  Asn Leu Lys 
    2285                 2290                 2295             


Lys Ile  Phe Gln Ala Ser Lys  Glu Pro Glu Asn Thr  Glu Pro Pro 
    2300                 2305                 2310             


Thr Val  Ile Arg Asp Asn Ile  Asn Trp Leu Arg Asp  Val Thr Ile 
    2315                 2320                 2325             


Phe Asp  Lys Gln Val Gln Pro  Arg Ser Pro Ala Glu  Val Asn Asn 
    2330                 2335                 2340             


Asn Pro  Cys Leu Glu Asn Asn  Gly Gly Cys Ser His  Leu Cys Phe 
    2345                 2350                 2355             


Ala Leu  Pro Gly Leu His Thr  Pro Lys Cys Asp Cys  Ala Phe Gly 
    2360                 2365                 2370             


Thr Leu  Gln Ser Asp Gly Lys  Asn Cys Ala Ile Ser  Thr Glu Asn 
    2375                 2380                 2385             


Phe Leu  Ile Phe Ala Leu Ser  Asn Ser Leu Arg Ser  Leu His Leu 
    2390                 2395                 2400             


Asp Pro  Glu Asn His Ser Pro  Pro Phe Gln Thr Ile  Asn Val Glu 
    2405                 2410                 2415             


Arg Thr  Val Met Ser Leu Asp  Tyr Asp Ser Val Ser  Asp Arg Ile 
    2420                 2425                 2430             


Tyr Phe  Thr Gln Asn Leu Ala  Ser Gly Val Gly Gln  Ile Ser Tyr 
    2435                 2440                 2445             


Ala Thr  Leu Ser Ser Gly Ile  His Thr Pro Thr Val  Ile Ala Ser 
    2450                 2455                 2460             


Gly Ile  Gly Thr Ala Asp Gly  Ile Ala Phe Asp Trp  Ile Thr Arg 
    2465                 2470                 2475             


Arg Ile  Tyr Tyr Ser Asp Tyr  Leu Asn Gln Met Ile  Asn Ser Met 
    2480                 2485                 2490             


Ala Glu  Asp Gly Ser Asn Arg  Thr Val Ile Ala Arg  Val Pro Lys 
    2495                 2500                 2505             


Pro Arg  Ala Ile Val Leu Asp  Pro Cys Gln Gly Tyr  Leu Tyr Trp 
    2510                 2515                 2520             


Ala Asp  Trp Asp Thr His Ala  Lys Ile Glu Arg Ala  Thr Leu Gly 
    2525                 2530                 2535             


Gly Asn  Phe Arg Val Pro Ile  Val Asn Ser Ser Leu  Val Met Pro 
    2540                 2545                 2550             


Ser Gly  Leu Thr Leu Asp Tyr  Glu Glu Asp Leu Leu  Tyr Trp Val 
    2555                 2560                 2565             


Asp Ala  Ser Leu Gln Arg Ile  Glu Arg Ser Thr Leu  Thr Gly Val 
    2570                 2575                 2580             


Asp Arg  Glu Val Ile Val Asn  Ala Ala Val His Ala  Phe Gly Leu 
    2585                 2590                 2595             


Thr Leu  Tyr Gly Gln Tyr Ile  Tyr Trp Thr Asp Leu  Tyr Thr Gln 
    2600                 2605                 2610             


Arg Ile  Tyr Arg Ala Asn Lys  Tyr Asp Gly Ser Gly  Gln Ile Ala 
    2615                 2620                 2625             


Met Thr  Thr Asn Leu Leu Ser  Gln Pro Arg Gly Ile  Asn Thr Val 
    2630                 2635                 2640             


Val Lys  Asn Gln Lys Gln Gln  Cys Asn Asn Pro Cys  Glu Gln Phe 
    2645                 2650                 2655             


Asn Gly  Gly Cys Ser His Ile  Cys Ala Pro Gly Pro  Asn Gly Ala 
    2660                 2665                 2670             


Glu Cys  Gln Cys Pro His Glu  Gly Asn Trp Tyr Leu  Ala Asn Asn 
    2675                 2680                 2685             


Arg Lys  His Cys Ile Val Asp  Asn Gly Glu Arg Cys  Gly Ala Ser 
    2690                 2695                 2700             


Ser Phe  Thr Cys Ser Asn Gly  Arg Cys Ile Ser Glu  Glu Trp Lys 
    2705                 2710                 2715             


Cys Asp  Asn Asp Asn Asp Cys  Gly Asp Gly Ser Asp  Glu Met Glu 
    2720                 2725                 2730             


Ser Val  Cys Ala Leu His Thr  Cys Ser Pro Thr Ala  Phe Thr Cys 
    2735                 2740                 2745             


Ala Asn  Gly Arg Cys Val Gln  Tyr Ser Tyr Arg Cys  Asp Tyr Tyr 
    2750                 2755                 2760             


Asn Asp  Cys Gly Asp Gly Ser  Asp Glu Ala Gly Cys  Leu Phe Arg 
    2765                 2770                 2775             


Asp Cys  Asn Ala Thr Thr Glu  Phe Met Cys Asn Asn  Arg Arg Cys 
    2780                 2785                 2790             


Ile Pro  Arg Glu Phe Ile Cys  Asn Gly Val Asp Asn  Cys His Asp 
    2795                 2800                 2805             


Asn Asn  Thr Ser Asp Glu Lys  Asn Cys Pro Asp Arg  Thr Cys Gln 
    2810                 2815                 2820             


Ser Gly  Tyr Thr Lys Cys His  Asn Ser Asn Ile Cys  Ile Pro Arg 
    2825                 2830                 2835             


Val Tyr  Leu Cys Asp Gly Asp  Asn Asp Cys Gly Asp  Asn Ser Asp 
    2840                 2845                 2850             


Glu Asn  Pro Thr Tyr Cys Thr  Thr His Thr Cys Ser  Ser Ser Glu 
    2855                 2860                 2865             


Phe Gln  Cys Ala Ser Gly Arg  Cys Ile Pro Gln His  Trp Tyr Cys 
    2870                 2875                 2880             


Asp Gln  Glu Thr Asp Cys Phe  Asp Ala Ser Asp Glu  Pro Ala Ser 
    2885                 2890                 2895             


Cys Gly  His Ser Glu Arg Thr  Cys Leu Ala Asp Glu  Phe Lys Cys 
    2900                 2905                 2910             


Asp Gly  Gly Arg Cys Ile Pro  Ser Glu Trp Ile Cys  Asp Gly Asp 
    2915                 2920                 2925             


Asn Asp  Cys Gly Asp Met Ser  Asp Glu Asp Lys Arg  His Gln Cys 
    2930                 2935                 2940             


Gln Asn  Gln Asn Cys Ser Asp  Ser Glu Phe Leu Cys  Val Asn Asp 
    2945                 2950                 2955             


Arg Pro  Pro Asp Arg Arg Cys  Ile Pro Gln Ser Trp  Val Cys Asp 
    2960                 2965                 2970             


Gly Asp  Val Asp Cys Thr Asp  Gly Tyr Asp Glu Asn  Gln Asn Cys 
    2975                 2980                 2985             


Thr Arg  Arg Thr Cys Ser Glu  Asn Glu Phe Thr Cys  Gly Tyr Gly 
    2990                 2995                 3000             


Leu Cys  Ile Pro Lys Ile Phe  Arg Cys Asp Arg His  Asn Asp Cys 
    3005                 3010                 3015             


Gly Asp  Tyr Ser Asp Glu Arg  Gly Cys Leu Tyr Gln  Thr Cys Gln 
    3020                 3025                 3030             


Gln Asn  Gln Phe Thr Cys Gln  Asn Gly Arg Cys Ile  Ser Lys Thr 
    3035                 3040                 3045             


Phe Val  Cys Asp Glu Asp Asn  Asp Cys Gly Asp Gly  Ser Asp Glu 
    3050                 3055                 3060             


Leu Met  His Leu Cys His Thr  Pro Glu Pro Thr Cys  Pro Pro His 
    3065                 3070                 3075             


Glu Phe  Lys Cys Asp Asn Gly  Arg Cys Ile Glu Met  Met Lys Leu 
    3080                 3085                 3090             


Cys Asn  His Leu Asp Asp Cys  Leu Asp Asn Ser Asp  Glu Lys Gly 
    3095                 3100                 3105             


Cys Gly  Ile Asn Glu Cys His  Asp Pro Ser Ile Ser  Gly Cys Asp 
    3110                 3115                 3120             


His Asn  Cys Thr Asp Thr Leu  Thr Ser Phe Tyr Cys  Ser Cys Arg 
    3125                 3130                 3135             


Pro Gly  Tyr Lys Leu Met Ser  Asp Lys Arg Thr Cys  Val Asp Ile 
    3140                 3145                 3150             


Asp Glu  Cys Thr Glu Met Pro  Phe Val Cys Ser Gln  Lys Cys Glu 
    3155                 3160                 3165             


Asn Val  Ile Gly Ser Tyr Ile  Cys Lys Cys Ala Pro  Gly Tyr Leu 
    3170                 3175                 3180             


Arg Glu  Pro Asp Gly Lys Thr  Cys Arg Gln Asn Ser  Asn Ile Glu 
    3185                 3190                 3195             


Pro Tyr  Leu Ile Phe Ser Asn  Arg Tyr Tyr Leu Arg  Asn Leu Thr 
    3200                 3205                 3210             


Ile Asp  Gly Tyr Phe Tyr Ser  Leu Ile Leu Glu Gly  Leu Asp Asn 
    3215                 3220                 3225             


Val Val  Ala Leu Asp Phe Asp  Arg Val Glu Lys Arg  Leu Tyr Trp 
    3230                 3235                 3240             


Ile Asp  Thr Gln Arg Gln Val  Ile Glu Arg Met Phe  Leu Asn Lys 
    3245                 3250                 3255             


Thr Asn  Lys Glu Thr Ile Ile  Asn His Arg Leu Pro  Ala Ala Glu 
    3260                 3265                 3270             


Ser Leu  Ala Val Asp Trp Val  Ser Arg Lys Leu Tyr  Trp Leu Asp 
    3275                 3280                 3285             


Ala Arg  Leu Asp Gly Leu Phe  Val Ser Asp Leu Asn  Gly Gly His 
    3290                 3295                 3300             


Arg Arg  Met Leu Ala Gln His  Cys Val Asp Ala Asn  Asn Thr Phe 
    3305                 3310                 3315             


Cys Phe  Asp Asn Pro Arg Gly  Leu Ala Leu His Pro  Gln Tyr Gly 
    3320                 3325                 3330             


Tyr Leu  Tyr Trp Ala Asp Trp  Gly His Arg Ala Tyr  Ile Gly Arg 
    3335                 3340                 3345             


Val Gly  Met Asp Gly Thr Asn  Lys Ser Val Ile Ile  Ser Thr Lys 
    3350                 3355                 3360             


Leu Glu  Trp Pro Asn Gly Ile  Thr Ile Asp Tyr Thr  Asn Asp Leu 
    3365                 3370                 3375             


Leu Tyr  Trp Ala Asp Ala His  Leu Gly Tyr Ile Glu  Tyr Ser Asp 
    3380                 3385                 3390             


Leu Glu  Gly His His Arg His  Thr Val Tyr Asp Gly  Ala Leu Pro 
    3395                 3400                 3405             


His Pro  Phe Ala Ile Thr Ile  Phe Glu Asp Thr Ile  Tyr Trp Thr 
    3410                 3415                 3420             


Asp Trp  Asn Thr Arg Thr Val  Glu Lys Gly Asn Lys  Tyr Asp Gly 
    3425                 3430                 3435             


Ser Asn  Arg Gln Thr Leu Val  Asn Thr Thr His Arg  Pro Phe Asp 
    3440                 3445                 3450             


Ile His  Val Tyr His Pro Tyr  Arg Gln Pro Ile Val  Ser Asn Pro 
    3455                 3460                 3465             


Cys Gly  Thr Asn Asn Gly Gly  Cys Ser His Leu Cys  Leu Ile Lys 
    3470                 3475                 3480             


Pro Gly  Gly Lys Gly Phe Thr  Cys Glu Cys Pro Asp  Asp Phe Arg 
    3485                 3490                 3495             


Thr Leu  Gln Leu Ser Gly Ser  Thr Tyr Cys Met Pro  Met Cys Ser 
    3500                 3505                 3510             


Ser Thr  Gln Phe Leu Cys Ala  Asn Asn Glu Lys Cys  Ile Pro Ile 
    3515                 3520                 3525             


Trp Trp  Lys Cys Asp Gly Gln  Lys Asp Cys Ser Asp  Gly Ser Asp 
    3530                 3535                 3540             


Glu Leu  Ala Leu Cys Pro Gln  Arg Phe Cys Arg Leu  Gly Gln Phe 
    3545                 3550                 3555             


Gln Cys  Ser Asp Gly Asn Cys  Thr Ser Pro Gln Thr  Leu Cys Asn 
    3560                 3565                 3570             


Ala His  Gln Asn Cys Pro Asp  Gly Ser Asp Glu Asp  Arg Leu Leu 
    3575                 3580                 3585             


Cys Glu  Asn His His Cys Asp  Ser Asn Glu Trp Gln  Cys Ala Asn 
    3590                 3595                 3600             


Lys Arg  Cys Ile Pro Glu Ser  Trp Gln Cys Asp Thr  Phe Asn Asp 
    3605                 3610                 3615             


Cys Glu  Asp Asn Ser Asp Glu  Asp Ser Ser His Cys  Ala Ser Arg 
    3620                 3625                 3630             


Thr Cys  Arg Pro Gly Gln Phe  Arg Cys Ala Asn Gly  Arg Cys Ile 
    3635                 3640                 3645             


Pro Gln  Ala Trp Lys Cys Asp  Val Asp Asn Asp Cys  Gly Asp His 
    3650                 3655                 3660             


Ser Asp  Glu Pro Ile Glu Glu  Cys Met Ser Ser Ala  His Leu Cys 
    3665                 3670                 3675             


Asp Asn  Phe Thr Glu Phe Ser  Cys Lys Thr Asn Tyr  Arg Cys Ile 
    3680                 3685                 3690             


Pro Lys  Trp Ala Val Cys Asn  Gly Val Asp Asp Cys  Arg Asp Asn 
    3695                 3700                 3705             


Ser Asp  Glu Gln Gly Cys Glu  Glu Arg Thr Cys His  Pro Val Gly 
    3710                 3715                 3720             


Asp Phe  Arg Cys Lys Asn His  His Cys Ile Pro Leu  Arg Trp Gln 
    3725                 3730                 3735             


Cys Asp  Gly Gln Asn Asp Cys  Gly Asp Asn Ser Asp  Glu Glu Asn 
    3740                 3745                 3750             


Cys Ala  Pro Arg Glu Cys Thr  Glu Ser Glu Phe Arg  Cys Val Asn 
    3755                 3760                 3765             


Gln Gln  Cys Ile Pro Ser Arg  Trp Ile Cys Asp His  Tyr Asn Asp 
    3770                 3775                 3780             


Cys Gly  Asp Asn Ser Asp Glu  Arg Asp Cys Glu Met  Arg Thr Cys 
    3785                 3790                 3795             


His Pro  Glu Tyr Phe Gln Cys  Thr Ser Gly His Cys  Val His Ser 
    3800                 3805                 3810             


Glu Leu  Lys Cys Asp Gly Ser  Ala Asp Cys Leu Asp  Ala Ser Asp 
    3815                 3820                 3825             


Glu Ala  Asp Cys Pro Thr Arg  Phe Pro Asp Gly Ala  Tyr Cys Gln 
    3830                 3835                 3840             


Ala Thr  Met Phe Glu Cys Lys  Asn His Val Cys Ile  Pro Pro Tyr 
    3845                 3850                 3855             


Trp Lys  Cys Asp Gly Asp Asp  Asp Cys Gly Asp Gly  Ser Asp Glu 
    3860                 3865                 3870             


Glu Leu  His Leu Cys Leu Asp  Val Pro Cys Asn Ser  Pro Asn Arg 
    3875                 3880                 3885             


Phe Arg  Cys Asp Asn Asn Arg  Cys Ile Tyr Ser His  Glu Val Cys 
    3890                 3895                 3900             


Asn Gly  Val Asp Asp Cys Gly  Asp Gly Thr Asp Glu  Thr Glu Glu 
    3905                 3910                 3915             


His Cys  Arg Lys Pro Thr Pro  Lys Pro Cys Thr Glu  Tyr Glu Tyr 
    3920                 3925                 3930             


Lys Cys  Gly Asn Gly His Cys  Ile Pro His Asp Asn  Val Cys Asp 
    3935                 3940                 3945             


Asp Ala  Asp Asp Cys Gly Asp  Trp Ser Asp Glu Leu  Gly Cys Asn 
    3950                 3955                 3960             


Lys Gly  Lys Glu Arg Thr Cys  Ala Glu Asn Ile Cys  Glu Gln Asn 
    3965                 3970                 3975             


Cys Thr  Gln Leu Asn Glu Gly  Gly Phe Ile Cys Ser  Cys Thr Ala 
    3980                 3985                 3990             


Gly Phe  Glu Thr Asn Val Phe  Asp Arg Thr Ser Cys  Leu Asp Ile 
    3995                 4000                 4005             


Asn Glu  Cys Glu Gln Phe Gly  Thr Cys Pro Gln His  Cys Arg Asn 
    4010                 4015                 4020             


Thr Lys  Gly Ser Tyr Glu Cys  Val Cys Ala Asp Gly  Phe Thr Ser 
    4025                 4030                 4035             


Met Ser  Asp Arg Pro Gly Lys  Arg Cys Ala Ala Glu  Gly Ser Ser 
    4040                 4045                 4050             


Pro Leu  Leu Leu Leu Pro Asp  Asn Val Arg Ile Arg  Lys Tyr Asn 
    4055                 4060                 4065             


Leu Ser  Ser Glu Arg Phe Ser  Glu Tyr Leu Gln Asp  Glu Glu Tyr 
    4070                 4075                 4080             


Ile Gln  Ala Val Asp Tyr Asp  Trp Asp Pro Lys Asp  Ile Gly Leu 
    4085                 4090                 4095             


Ser Val  Val Tyr Tyr Thr Val  Arg Gly Glu Gly Ser  Arg Phe Gly 
    4100                 4105                 4110             


Ala Ile  Lys Arg Ala Tyr Ile  Pro Asn Phe Glu Ser  Gly Arg Asn 
    4115                 4120                 4125             


Asn Leu  Val Gln Glu Val Asp  Leu Lys Leu Lys Tyr  Val Met Gln 
    4130                 4135                 4140             


Pro Asp  Gly Ile Ala Val Asp  Trp Val Gly Arg His  Ile Tyr Trp 
    4145                 4150                 4155             


Ser Asp  Val Lys Asn Lys Arg  Ile Glu Val Ala Lys  Leu Asp Gly 
    4160                 4165                 4170             


Arg Tyr  Arg Lys Trp Leu Ile  Ser Thr Asp Leu Asp  Gln Pro Ala 
    4175                 4180                 4185             


Ala Ile  Ala Val Asn Pro Lys  Leu Gly Leu Met Phe  Trp Thr Asp 
    4190                 4195                 4200             


Trp Gly  Lys Glu Pro Lys Ile  Glu Ser Ala Trp Met  Asn Gly Glu 
    4205                 4210                 4215             


Asp Arg  Asn Ile Leu Val Phe  Glu Asp Leu Gly Trp  Pro Thr Gly 
    4220                 4225                 4230             


Leu Ser  Ile Asp Tyr Leu Asn  Asn Asp Arg Ile Tyr  Trp Ser Asp 
    4235                 4240                 4245             


Phe Lys  Glu Asp Val Ile Glu  Thr Ile Lys Tyr Asp  Gly Thr Asp 
    4250                 4255                 4260             


Arg Arg  Val Ile Ala Lys Glu  Ala Met Asn Pro Tyr  Ser Leu Asp 
    4265                 4270                 4275             


Ile Phe  Glu Asp Gln Leu Tyr  Trp Ile Ser Lys Glu  Lys Gly Glu 
    4280                 4285                 4290             


Val Trp  Lys Gln Asn Lys Phe  Gly Gln Gly Lys Lys  Glu Lys Thr 
    4295                 4300                 4305             


Leu Val  Val Asn Pro Trp Leu  Thr Gln Val Arg Ile  Phe His Gln 
    4310                 4315                 4320             


Leu Arg  Tyr Asn Lys Ser Val  Pro Asn Leu Cys Lys  Gln Ile Cys 
    4325                 4330                 4335             


Ser His  Leu Cys Leu Leu Arg  Pro Gly Gly Tyr Ser  Cys Ala Cys 
    4340                 4345                 4350             


Pro Gln  Gly Ser Ser Phe Ile  Glu Gly Ser Thr Thr  Glu Cys Asp 
    4355                 4360                 4365             


Ala Ala  Ile Glu Leu Pro Ile  Asn Leu Pro Pro Pro  Cys Arg Cys 
    4370                 4375                 4380             


Met His  Gly Gly Asn Cys Tyr  Phe Asp Glu Thr Asp  Leu Pro Lys 
    4385                 4390                 4395             


Cys Lys  Cys Pro Ser Gly Tyr  Thr Gly Lys Tyr Cys  Glu Met Ala 
    4400                 4405                 4410             


Phe Ser  Lys Gly Ile Ser Pro  Gly Thr Thr Ala Val  Ala Val Leu 
    4415                 4420                 4425             


Leu Thr  Ile Leu Leu Ile Val  Val Ile Gly Ala Leu  Ala Ile Ala 
    4430                 4435                 4440             


Gly Phe  Phe His Tyr Arg Arg  Thr Gly Ser Leu Leu  Pro Ala Leu 
    4445                 4450                 4455             


Pro Lys  Leu Pro Ser Leu Ser  Ser Leu Val Lys Pro  Ser Glu Asn 
    4460                 4465                 4470             


Gly Asn  Gly Val Thr Phe Arg  Ser Gly Ala Asp Leu  Asn Met Asp 
    4475                 4480                 4485             


Ile Gly  Val Ser Gly Phe Gly  Pro Glu Thr Ala Ile  Asp Arg Ser 
    4490                 4495                 4500             


Met Ala  Met Ser Glu Asp Phe  Val Met Glu Met Gly  Lys Gln Pro 
    4505                 4510                 4515             


Ile Ile  Phe Glu Asn Pro Met  Tyr Ser Ala Arg Asp  Ser Ala Val 
    4520                 4525                 4530             


Lys Val  Val Gln Pro Ile Gln  Val Thr Val Ser Glu  Asn Val Asp 
    4535                 4540                 4545             


Asn Lys  Asn Tyr Gly Ser Pro  Ile Asn Pro Ser Glu  Ile Val Pro 
    4550                 4555                 4560             


Glu Thr  Asn Pro Thr Ser Pro  Ala Ala Asp Gly Thr  Gln Val Thr 
    4565                 4570                 4575             


Lys Trp  Asn Leu Phe Lys Arg  Lys Ser Lys Gln Thr  Thr Asn Phe 
    4580                 4585                 4590             


Glu Asn  Pro Ile Tyr Ala Gln  Met Glu Asn Glu Gln  Lys Glu Ser 
    4595                 4600                 4605             


Val Ala  Ala Thr Pro Pro Pro  Ser Pro Ser Leu Pro  Ala Lys Pro 
    4610                 4615                 4620             


Lys Pro  Pro Ser Arg Arg Asp  Pro Thr Pro Thr Tyr  Ser Ala Thr 
    4625                 4630                 4635             


Glu Asp  Thr Phe Lys Asp Thr  Ala Asn Leu Val Lys  Glu Asp Ser 
    4640                 4645                 4650             


Glu Val  
    4655 


<210>  3791
<211>  708
<212>  PRT
<213>  homo sapiens

<400>  3791

Met Lys Asp Met Pro Leu Arg Ile His Val Leu Leu Gly Leu Ala Ile 
1               5                   10                  15      


Thr Thr Leu Val Gln Ala Val Asp Lys Lys Val Asp Cys Pro Arg Leu 
            20                  25                  30          


Cys Thr Cys Glu Ile Arg Pro Trp Phe Thr Pro Arg Ser Ile Tyr Met 
        35                  40                  45              


Glu Ala Ser Thr Val Asp Cys Asn Asp Leu Gly Leu Leu Thr Phe Pro 
    50                  55                  60                  


Ala Arg Leu Pro Ala Asn Thr Gln Ile Leu Leu Leu Gln Thr Asn Asn 
65                  70                  75                  80  


Ile Ala Lys Ile Glu Tyr Ser Thr Asp Phe Pro Val Asn Leu Thr Gly 
                85                  90                  95      


Leu Asp Leu Ser Gln Asn Asn Leu Ser Ser Val Thr Asn Ile Asn Val 
            100                 105                 110         


Lys Lys Met Pro Gln Leu Leu Ser Val Tyr Leu Glu Glu Asn Lys Leu 
        115                 120                 125             


Thr Glu Leu Pro Glu Lys Cys Leu Ser Glu Leu Ser Asn Leu Gln Glu 
    130                 135                 140                 


Leu Tyr Ile Asn His Asn Leu Leu Ser Thr Ile Ser Pro Gly Ala Phe 
145                 150                 155                 160 


Ile Gly Leu His Asn Leu Leu Arg Leu His Leu Asn Ser Asn Arg Leu 
                165                 170                 175     


Gln Met Ile Asn Ser Lys Trp Phe Asp Ala Leu Pro Asn Leu Glu Ile 
            180                 185                 190         


Leu Met Ile Gly Glu Asn Pro Ile Ile Arg Ile Lys Asp Met Asn Phe 
        195                 200                 205             


Lys Pro Leu Ile Asn Leu Arg Ser Leu Val Ile Ala Gly Ile Asn Leu 
    210                 215                 220                 


Thr Glu Ile Pro Asp Asn Ala Leu Val Gly Leu Glu Asn Leu Glu Ser 
225                 230                 235                 240 


Ile Ser Phe Tyr Asp Asn Arg Leu Ile Lys Val Pro His Val Ala Leu 
                245                 250                 255     


Gln Lys Val Val Asn Leu Lys Phe Leu Asp Leu Asn Lys Asn Pro Ile 
            260                 265                 270         


Asn Arg Ile Arg Arg Gly Asp Phe Ser Asn Met Leu His Leu Lys Glu 
        275                 280                 285             


Leu Gly Ile Asn Asn Met Pro Glu Leu Ile Ser Ile Asp Ser Leu Ala 
    290                 295                 300                 


Val Asp Asn Leu Pro Asp Leu Arg Lys Ile Glu Ala Thr Asn Asn Pro 
305                 310                 315                 320 


Arg Leu Ser Tyr Ile His Pro Asn Ala Phe Phe Arg Leu Pro Lys Leu 
                325                 330                 335     


Glu Ser Leu Met Leu Asn Ser Asn Ala Leu Ser Ala Leu Tyr His Gly 
            340                 345                 350         


Thr Ile Glu Ser Leu Pro Asn Leu Lys Glu Ile Ser Ile His Ser Asn 
        355                 360                 365             


Pro Ile Arg Cys Asp Cys Val Ile Arg Trp Met Asn Met Asn Lys Thr 
    370                 375                 380                 


Asn Ile Arg Phe Met Glu Pro Asp Ser Leu Phe Cys Val Asp Pro Pro 
385                 390                 395                 400 


Glu Phe Gln Gly Gln Asn Val Arg Gln Val His Phe Arg Asp Met Met 
                405                 410                 415     


Glu Ile Cys Leu Pro Leu Ile Ala Pro Glu Ser Phe Pro Ser Asn Leu 
            420                 425                 430         


Asn Val Glu Ala Gly Ser Tyr Val Ser Phe His Cys Arg Ala Thr Ala 
        435                 440                 445             


Glu Pro Gln Pro Glu Ile Tyr Trp Ile Thr Pro Ser Gly Gln Lys Leu 
    450                 455                 460                 


Leu Pro Asn Thr Leu Thr Asp Lys Phe Tyr Val His Ser Glu Gly Thr 
465                 470                 475                 480 


Leu Asp Ile Asn Gly Val Thr Pro Lys Glu Gly Gly Leu Tyr Thr Cys 
                485                 490                 495     


Ile Ala Thr Asn Leu Val Gly Ala Asp Leu Lys Ser Val Met Ile Lys 
            500                 505                 510         


Val Asp Gly Ser Phe Pro Gln Asp Asn Asn Gly Ser Leu Asn Ile Lys 
        515                 520                 525             


Ile Arg Asp Ile Gln Ala Asn Ser Val Leu Val Ser Trp Lys Ala Ser 
    530                 535                 540                 


Ser Lys Ile Leu Lys Ser Ser Val Lys Trp Thr Ala Phe Val Lys Thr 
545                 550                 555                 560 


Glu Asn Ser His Ala Ala Gln Ser Ala Arg Ile Pro Ser Asp Val Lys 
                565                 570                 575     


Val Tyr Asn Leu Thr His Leu Asn Pro Ser Thr Glu Tyr Lys Ile Cys 
            580                 585                 590         


Ile Asp Ile Pro Thr Ile Tyr Gln Lys Asn Arg Lys Lys Cys Val Asn 
        595                 600                 605             


Val Thr Thr Lys Gly Leu His Pro Asp Gln Lys Glu Tyr Glu Lys Asn 
    610                 615                 620                 


Asn Thr Thr Thr Leu Met Ala Cys Leu Gly Gly Leu Leu Gly Ile Ile 
625                 630                 635                 640 


Gly Val Ile Cys Leu Ile Ser Cys Leu Ser Pro Glu Met Asn Cys Asp 
                645                 650                 655     


Gly Gly His Ser Tyr Val Arg Asn Tyr Leu Gln Lys Pro Thr Phe Ala 
            660                 665                 670         


Leu Gly Glu Leu Tyr Pro Pro Leu Ile Asn Leu Trp Glu Ala Gly Lys 
        675                 680                 685             


Glu Lys Ser Thr Ser Leu Lys Val Lys Ala Thr Val Ile Gly Leu Pro 
    690                 695                 700                 


Thr Asn Met Ser 
705             


<210>  3792
<211>  816
<212>  PRT
<213>  homo sapiens

<400>  3792

Met Ser Ser Glu Cys Asp Gly Gly Ser Lys Ala Val Met Asn Gly Leu 
1               5                   10                  15      


Ala Pro Gly Ser Asn Gly Gln Asp Lys Asp Met Asp Pro Thr Lys Ile 
            20                  25                  30          


Cys Thr Gly Lys Gly Ala Val Thr Leu Arg Ala Ser Ser Ser Tyr Arg 
        35                  40                  45              


Glu Thr Pro Ser Ser Ser Pro Ala Ser Pro Gln Glu Thr Arg Gln His 
    50                  55                  60                  


Glu Ser Lys Pro Gly Leu Glu Pro Glu Pro Ser Ser Ala Asp Glu Trp 
65                  70                  75                  80  


Arg Leu Ser Ser Ser Ala Asp Ala Asn Gly Asn Ala Gln Pro Ser Ser 
                85                  90                  95      


Leu Ala Ala Lys Gly Tyr Arg Ser Val His Pro Asn Leu Pro Ser Asp 
            100                 105                 110         


Lys Ser Gln Asp Ala Thr Ser Ser Ser Ala Ala Gln Pro Glu Val Ile 
        115                 120                 125             


Val Val Pro Leu Tyr Leu Val Asn Thr Asp Arg Gly Gln Glu Gly Thr 
    130                 135                 140                 


Ala Arg Pro Pro Thr Pro Leu Gly Pro Leu Gly Cys Val Pro Thr Ile 
145                 150                 155                 160 


Pro Ala Thr Ala Ser Ala Ala Ser Pro Leu Thr Phe Pro Thr Leu Asp 
                165                 170                 175     


Asp Phe Ile Pro Pro His Leu Gln Arg Trp Pro His His Ser Gln Pro 
            180                 185                 190         


Ala Arg Ala Ser Gly Ser Phe Ala Pro Ile Ser Gln Thr Pro Pro Ser 
        195                 200                 205             


Phe Ser Pro Pro Pro Pro Leu Val Pro Pro Ala Pro Glu Asp Leu Arg 
    210                 215                 220                 


Arg Val Ser Glu Pro Asp Leu Thr Gly Ala Val Ser Ser Thr Asp Ser 
225                 230                 235                 240 


Ser Pro Leu Leu Asn Glu Val Ser Ser Ser Leu Ile Gly Thr Asp Ser 
                245                 250                 255     


Gln Ala Phe Pro Ser Val Ser Lys Pro Ser Ser Ala Tyr Pro Ser Thr 
            260                 265                 270         


Thr Ile Val Asn Pro Thr Ile Val Leu Leu Gln His Asn Arg Glu Gln 
        275                 280                 285             


Gln Lys Arg Leu Ser Ser Leu Ser Asp Pro Val Ser Glu Arg Arg Val 
    290                 295                 300                 


Gly Glu Gln Asp Ser Ala Pro Thr Gln Glu Lys Pro Thr Ser Pro Gly 
305                 310                 315                 320 


Lys Ala Ile Glu Lys Arg Ala Lys Asp Asp Ser Arg Arg Val Val Lys 
                325                 330                 335     


Ser Thr Gln Asp Leu Ser Asp Val Ser Met Asp Glu Val Gly Ile Pro 
            340                 345                 350         


Leu Arg Asn Thr Glu Arg Ser Lys Asp Trp Tyr Lys Thr Met Phe Lys 
        355                 360                 365             


Gln Ile His Lys Leu Asn Arg Asp Asp Asp Ser Asp Leu Tyr Ser Pro 
    370                 375                 380                 


Arg Tyr Ser Phe Ser Glu Asp Thr Lys Ser Pro Leu Ser Val Pro Arg 
385                 390                 395                 400 


Ser Lys Ser Glu Met Ser Tyr Ile Asp Gly Glu Lys Val Val Lys Arg 
                405                 410                 415     


Ser Ala Thr Leu Pro Leu Pro Ala Arg Ser Ser Ser Leu Lys Ser Ser 
            420                 425                 430         


Ser Glu Arg Asn Asp Trp Glu Pro Pro Asp Lys Lys Val Asp Thr Arg 
        435                 440                 445             


Lys Tyr Arg Ala Glu Pro Lys Ser Ile Tyr Glu Tyr Gln Pro Gly Lys 
    450                 455                 460                 


Ser Ser Val Leu Thr Asn Glu Lys Met Ser Ser Ala Ile Ser Pro Thr 
465                 470                 475                 480 


Pro Glu Ile Ser Ser Glu Thr Pro Gly Tyr Ile Tyr Ser Ser Asn Phe 
                485                 490                 495     


His Ala Val Lys Arg Glu Ser Asp Gly Ala Pro Gly Asp Leu Thr Ser 
            500                 505                 510         


Leu Glu Asn Glu Arg Gln Ile Tyr Lys Ser Val Leu Glu Gly Gly Asp 
        515                 520                 525             


Ile Pro Leu Gln Gly Leu Ser Gly Leu Lys Arg Pro Ser Ser Ser Ala 
    530                 535                 540                 


Ser Thr Lys Asp Ser Glu Ser Pro Arg His Phe Ile Pro Ala Asp Tyr 
545                 550                 555                 560 


Leu Glu Ser Thr Glu Glu Phe Ile Arg Arg Arg His Asp Asp Lys Glu 
                565                 570                 575     


Met Arg Pro Ala Arg Ala Lys Phe Asp Phe Lys Ala Gln Thr Leu Lys 
            580                 585                 590         


Glu Leu Pro Leu Gln Lys Gly Asp Ile Val Tyr Ile Tyr Lys Gln Ile 
        595                 600                 605             


Asp Gln Asn Trp Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe 
    610                 615                 620                 


Pro Arg Thr Tyr Ile Glu Leu Leu Pro Pro Ala Glu Lys Ala Gln Pro 
625                 630                 635                 640 


Lys Lys Leu Thr Pro Val Gln Val Leu Glu Tyr Gly Glu Ala Ile Ala 
                645                 650                 655     


Lys Phe Asn Phe Asn Gly Asp Thr Gln Val Glu Met Ser Phe Arg Lys 
            660                 665                 670         


Gly Glu Arg Ile Thr Leu Leu Arg Gln Val Asp Glu Asn Trp Tyr Glu 
        675                 680                 685             


Gly Arg Ile Pro Gly Thr Ser Arg Gln Gly Ile Phe Pro Ile Thr Tyr 
    690                 695                 700                 


Val Asp Val Ile Lys Arg Pro Leu Val Lys Asn Pro Val Asp Tyr Met 
705                 710                 715                 720 


Asp Leu Pro Phe Ser Ser Ser Pro Ser Arg Ser Ala Thr Ala Ser Pro 
                725                 730                 735     


Gln Gln Pro Gln Ala Gln Gln Arg Arg Val Thr Pro Asp Arg Ser Gln 
            740                 745                 750         


Thr Ser Gln Asp Leu Phe Ser Tyr Gln Ala Leu Tyr Ser Tyr Ile Pro 
        755                 760                 765             


Gln Asn Asp Asp Glu Leu Glu Leu Arg Asp Gly Asp Ile Val Asp Val 
    770                 775                 780                 


Met Glu Lys Cys Asp Asp Gly Trp Phe Val Gly Thr Ser Arg Arg Thr 
785                 790                 795                 800 


Lys Gln Phe Gly Thr Phe Pro Gly Asn Tyr Val Lys Pro Leu Tyr Leu 
                805                 810                 815     


<210>  3793
<211>  632
<212>  PRT
<213>  homo sapiens

<400>  3793

Met Ser Arg Val Arg Asp Ala Gly Cys Val Ala Ala Gly Ile Val Ile 
1               5                   10                  15      


Gly Ala Gly Ala Trp Tyr Cys Val Tyr Lys Tyr Thr Arg Gly Arg Asp 
            20                  25                  30          


Gln Thr Lys Lys Arg Met Ala Lys Pro Lys Asn Arg Ala Val Ala Gly 
        35                  40                  45              


Thr Gly Ala Arg Ala Arg Ala Gly Leu Arg Ala Gly Phe Thr Ile Asp 
    50                  55                  60                  


Leu Gly Ser Gly Phe Ser Pro Pro Thr Pro Val Arg Ala Glu Ala Glu 
65                  70                  75                  80  


Asp Arg Ala Gln Asp Glu Ala Ser Ala Leu Asp Thr Val Gly Ala Glu 
                85                  90                  95      


Ala Val Ala Pro Ala Ala Ser Ser Ala Glu Ala Gln Ser Gly Ala Gly 
            100                 105                 110         


Ser Gln Ala Gln Glu Ala Asp Gly Ala Gly Val Gly Pro Lys Ala Glu 
        115                 120                 125             


Ser Val Val Gly Ala Ala Met Ala Ser Ala Ile Ala Pro Pro Pro Gly 
    130                 135                 140                 


Val Thr Glu Ala Leu Gly Ala Ala Glu Ala Pro Ala Met Ala Gly Ala 
145                 150                 155                 160 


Pro Lys Val Ala Glu Ala Pro Arg Glu Ala Glu Thr Ser Arg Ala Ala 
                165                 170                 175     


Val Pro Pro Gly Thr Val Val Pro Thr Glu Ala Ala Ala Pro Thr Glu 
            180                 185                 190         


Val Thr Glu Gly Pro Gly Val Ala Ala Pro Thr Lys Val Ala Glu Ala 
        195                 200                 205             


Pro Gly Val Ala Ser Pro Thr Glu Ala Ala Glu Ala Pro Val Pro Ala 
    210                 215                 220                 


Thr Pro Thr Gly Ala Ala Ala Pro Thr Gly Ala Ala Glu Ser Pro Gly 
225                 230                 235                 240 


Thr Ser Gly Ser Pro Arg Thr Ala Val Val Pro Gly Thr Ser Ala Ala 
                245                 250                 255     


Lys Lys Ala Thr Pro Gly Ala His Thr Gly Ala Ile Pro Lys Ala Thr 
            260                 265                 270         


Ser Ala Thr Gly Ala Val Pro Lys Gly Gly Gly Lys Gly Val Thr Arg 
        275                 280                 285             


Ser Arg Asn Gly Gly Lys Gly Lys Gly Lys Lys Ser Lys Val Glu Val 
    290                 295                 300                 


Asp Glu Leu Gly Met Gly Phe Arg Pro Gly Asp Gly Ala Ala Ala Ala 
305                 310                 315                 320 


Ala Ala Ala Ser Ala Asn Gly Gly Gln Ala Phe Leu Ala Glu Val Pro 
                325                 330                 335     


Asp Ser Glu Glu Gly Glu Ser Gly Trp Thr Asp Thr Glu Ser Asp Ser 
            340                 345                 350         


Asp Ser Glu Pro Glu Thr Gln Arg Arg Gly Arg Gly Arg Arg Pro Val 
        355                 360                 365             


Ala Met Gln Lys Arg Pro Phe Pro Tyr Glu Ile Asp Glu Ile Leu Gly 
    370                 375                 380                 


Val Arg Asp Leu Arg Lys Val Leu Ala Leu Leu Gln Lys Ser Asp Asp 
385                 390                 395                 400 


Pro Phe Ile Gln Gln Val Ala Leu Leu Thr Leu Ser Asn Asn Ala Asn 
                405                 410                 415     


Tyr Ser Cys Asn Gln Glu Thr Ile Arg Lys Leu Gly Gly Leu Pro Ile 
            420                 425                 430         


Ile Ala Asn Met Ile Asn Lys Thr Asp Pro His Ile Lys Glu Lys Ala 
        435                 440                 445             


Leu Met Ala Met Asn Asn Leu Ser Glu Asn Tyr Glu Asn Gln Gly Arg 
    450                 455                 460                 


Leu Gln Val Tyr Met Asn Lys Val Met Asp Asp Ile Met Ala Ser Asn 
465                 470                 475                 480 


Leu Asn Ser Ala Val Gln Val Val Gly Leu Lys Phe Leu Thr Asn Met 
                485                 490                 495     


Thr Ile Thr Asn Asp Tyr Gln His Leu Leu Val Asn Ser Ile Ala Asn 
            500                 505                 510         


Phe Phe Arg Leu Leu Ser Gln Gly Gly Gly Lys Ile Lys Val Glu Ile 
        515                 520                 525             


Leu Lys Ile Leu Ser Asn Phe Ala Glu Asn Pro Asp Met Leu Lys Lys 
    530                 535                 540                 


Leu Leu Ser Thr Gln Val Pro Ala Ser Phe Ser Ser Leu Tyr Asn Ser 
545                 550                 555                 560 


Tyr Val Glu Ser Glu Ile Leu Ile Asn Ala Leu Thr Leu Phe Glu Ile 
                565                 570                 575     


Ile Tyr Asp Asn Leu Arg Ala Glu Val Phe Asn Tyr Arg Glu Phe Asn 
            580                 585                 590         


Lys Gly Ser Leu Phe Tyr Leu Cys Thr Thr Ser Gly Val Cys Val Lys 
        595                 600                 605             


Lys Ile Arg Ala Leu Ala Asn His His Asp Leu Leu Val Lys Val Lys 
    610                 615                 620                 


Val Ile Lys Leu Val Asn Lys Phe 
625                 630         


<210>  3794
<211>  802
<212>  PRT
<213>  homo sapiens

<400>  3794

Met Pro Arg Ile Met Ile Lys Gly Gly Val Trp Arg Asn Thr Glu Asp 
1               5                   10                  15      


Glu Ile Leu Lys Ala Ala Val Met Lys Tyr Gly Lys Asn Gln Trp Ser 
            20                  25                  30          


Arg Ile Ala Ser Leu Leu His Arg Lys Ser Ala Lys Gln Cys Lys Ala 
        35                  40                  45              


Arg Trp Tyr Glu Trp Leu Asp Pro Ser Ile Lys Lys Thr Glu Trp Ser 
    50                  55                  60                  


Arg Glu Glu Glu Glu Lys Leu Leu His Leu Ala Lys Leu Met Pro Thr 
65                  70                  75                  80  


Gln Trp Arg Thr Ile Ala Pro Ile Ile Gly Arg Thr Ala Ala Gln Cys 
                85                  90                  95      


Leu Glu His Tyr Glu Phe Leu Leu Asp Lys Ala Ala Gln Arg Asp Asn 
            100                 105                 110         


Glu Glu Glu Thr Thr Asp Asp Pro Arg Lys Leu Lys Pro Gly Glu Ile 
        115                 120                 125             


Asp Pro Asn Pro Glu Thr Lys Pro Ala Arg Pro Asp Pro Ile Asp Met 
    130                 135                 140                 


Asp Glu Asp Glu Leu Glu Met Leu Ser Glu Ala Arg Ala Arg Leu Ala 
145                 150                 155                 160 


Asn Thr Gln Gly Lys Lys Ala Lys Arg Lys Ala Arg Glu Lys Gln Leu 
                165                 170                 175     


Glu Glu Ala Arg Arg Leu Ala Ala Leu Gln Lys Arg Arg Glu Leu Arg 
            180                 185                 190         


Ala Ala Gly Ile Glu Ile Gln Lys Lys Arg Lys Arg Lys Arg Gly Val 
        195                 200                 205             


Asp Tyr Asn Ala Glu Ile Pro Phe Glu Lys Lys Pro Ala Leu Gly Phe 
    210                 215                 220                 


Tyr Asp Thr Ser Glu Glu Asn Tyr Gln Ala Leu Asp Ala Asp Phe Arg 
225                 230                 235                 240 


Lys Leu Arg Gln Gln Asp Leu Asp Gly Glu Leu Arg Ser Glu Lys Glu 
                245                 250                 255     


Gly Arg Asp Arg Lys Lys Asp Lys Gln His Leu Lys Arg Lys Lys Glu 
            260                 265                 270         


Ser Asp Leu Pro Ser Ala Ile Leu Gln Thr Ser Gly Val Ser Glu Phe 
        275                 280                 285             


Thr Lys Lys Arg Ser Lys Leu Val Leu Pro Ala Pro Gln Ile Ser Asp 
    290                 295                 300                 


Ala Glu Leu Gln Glu Val Val Lys Val Gly Gln Ala Ser Glu Ile Ala 
305                 310                 315                 320 


Arg Gln Thr Ala Glu Glu Ser Gly Ile Thr Asn Ser Ala Ser Ser Thr 
                325                 330                 335     


Leu Leu Ser Glu Tyr Asn Val Thr Asn Asn Ser Val Ala Leu Arg Thr 
            340                 345                 350         


Pro Arg Thr Pro Ala Ser Gln Asp Arg Ile Leu Gln Glu Ala Gln Asn 
        355                 360                 365             


Leu Met Ala Leu Thr Asn Val Asp Thr Pro Leu Lys Gly Gly Leu Asn 
    370                 375                 380                 


Thr Pro Leu His Glu Ser Asp Phe Ser Gly Val Thr Pro Gln Arg Gln 
385                 390                 395                 400 


Val Val Gln Thr Pro Asn Thr Val Leu Ser Thr Pro Phe Arg Thr Pro 
                405                 410                 415     


Ser Asn Gly Ala Glu Gly Leu Thr Pro Arg Ser Gly Thr Thr Pro Lys 
            420                 425                 430         


Pro Val Ile Asn Ser Thr Pro Gly Arg Thr Pro Leu Arg Asp Lys Leu 
        435                 440                 445             


Asn Ile Asn Pro Glu Asp Gly Met Ala Asp Tyr Ser Asp Pro Ser Tyr 
    450                 455                 460                 


Val Lys Gln Met Glu Arg Glu Ser Arg Glu His Leu Arg Leu Gly Leu 
465                 470                 475                 480 


Leu Gly Leu Pro Ala Pro Lys Asn Asp Phe Glu Ile Val Leu Pro Glu 
                485                 490                 495     


Asn Ala Glu Lys Glu Leu Glu Glu Arg Glu Ile Asp Asp Thr Tyr Ile 
            500                 505                 510         


Glu Asp Ala Ala Asp Val Asp Ala Arg Lys Gln Ala Ile Arg Asp Ala 
        515                 520                 525             


Glu Arg Val Lys Glu Met Lys Arg Met His Lys Ala Val Gln Lys Asp 
    530                 535                 540                 


Leu Pro Arg Pro Ser Glu Val Asn Glu Thr Ile Leu Arg Pro Leu Asn 
545                 550                 555                 560 


Val Glu Pro Pro Leu Thr Asp Leu Gln Lys Ser Glu Glu Leu Ile Lys 
                565                 570                 575     


Lys Glu Met Ile Thr Met Leu His Tyr Asp Leu Leu His His Pro Tyr 
            580                 585                 590         


Glu Pro Ser Gly Asn Lys Lys Gly Lys Thr Val Gly Phe Gly Thr Asn 
        595                 600                 605             


Asn Ser Glu His Ile Thr Tyr Leu Glu His Asn Pro Tyr Glu Lys Phe 
    610                 615                 620                 


Ser Lys Glu Glu Leu Lys Lys Ala Gln Asp Val Leu Val Gln Glu Met 
625                 630                 635                 640 


Glu Val Val Lys Gln Gly Met Ser His Gly Glu Leu Ser Ser Glu Ala 
                645                 650                 655     


Tyr Asn Gln Val Trp Glu Glu Cys Tyr Ser Gln Val Leu Tyr Leu Pro 
            660                 665                 670         


Gly Gln Ser Arg Tyr Thr Arg Ala Asn Leu Ala Ser Lys Lys Asp Arg 
        675                 680                 685             


Ile Glu Ser Leu Glu Lys Arg Leu Glu Ile Asn Arg Gly His Met Thr 
    690                 695                 700                 


Thr Glu Ala Lys Arg Ala Ala Lys Met Glu Lys Lys Met Lys Ile Leu 
705                 710                 715                 720 


Leu Gly Gly Tyr Gln Ser Arg Ala Met Gly Leu Met Lys Gln Leu Asn 
                725                 730                 735     


Asp Leu Trp Asp Gln Ile Glu Gln Ala His Leu Glu Leu Arg Thr Phe 
            740                 745                 750         


Glu Glu Leu Lys Lys His Glu Asp Ser Ala Ile Pro Arg Arg Leu Glu 
        755                 760                 765             


Cys Leu Lys Glu Asp Val Gln Arg Gln Gln Glu Arg Glu Lys Glu Leu 
    770                 775                 780                 


Gln His Arg Tyr Ala Asp Leu Leu Leu Glu Lys Glu Thr Leu Lys Ser 
785                 790                 795                 800 


Lys Phe 
        


<210>  3795
<211>  558
<212>  PRT
<213>  homo sapiens

<400>  3795

Met Glu Ala Ala Ala Gln Phe Phe Val Glu Ser Pro Asp Val Val Tyr 
1               5                   10                  15      


Gly Pro Glu Ala Ile Glu Ala Gln Tyr Glu Tyr Arg Thr Thr Arg Val 
            20                  25                  30          


Ser Arg Glu Gly Gly Val Leu Lys Val His Pro Thr Ser Thr Arg Phe 
        35                  40                  45              


Thr Phe Arg Thr Ala Arg Gln Val Pro Arg Leu Gly Val Met Leu Val 
    50                  55                  60                  


Gly Trp Gly Gly Asn Asn Gly Ser Thr Leu Thr Ala Ala Val Leu Ala 
65                  70                  75                  80  


Asn Arg Leu Arg Leu Ser Trp Pro Thr Arg Ser Gly Arg Lys Glu Ala 
                85                  90                  95      


Asn Tyr Tyr Gly Ser Leu Thr Gln Ala Gly Thr Val Ser Leu Gly Leu 
            100                 105                 110         


Asp Ala Glu Gly Gln Glu Val Phe Val Pro Phe Ser Ala Val Leu Pro 
        115                 120                 125             


Met Val Ala Pro Asn Asp Leu Val Phe Asp Gly Trp Asp Ile Ser Ser 
    130                 135                 140                 


Leu Asn Leu Ala Glu Ala Met Arg Arg Ala Lys Val Leu Asp Trp Gly 
145                 150                 155                 160 


Leu Gln Glu Gln Leu Trp Pro His Met Glu Ala Leu Arg Pro Arg Pro 
                165                 170                 175     


Ser Val Tyr Ile Pro Glu Phe Ile Ala Ala Asn Gln Ser Ala Arg Ala 
            180                 185                 190         


Asp Asn Leu Ile Pro Gly Ser Arg Ala Gln Gln Leu Glu Gln Ile Arg 
        195                 200                 205             


Arg Asp Ile Arg Asp Phe Arg Ser Ser Ala Gly Leu Asp Lys Val Ile 
    210                 215                 220                 


Val Leu Trp Thr Ala Asn Thr Glu Arg Phe Cys Glu Val Ile Pro Gly 
225                 230                 235                 240 


Leu Asn Asp Thr Ala Glu Asn Leu Leu Arg Thr Ile Glu Leu Gly Leu 
                245                 250                 255     


Glu Val Ser Pro Ser Thr Leu Phe Ala Val Ala Ser Ile Leu Glu Gly 
            260                 265                 270         


Cys Ala Phe Leu Asn Gly Ser Pro Gln Asn Thr Leu Val Pro Gly Ala 
        275                 280                 285             


Leu Glu Leu Ala Trp Gln His Arg Val Phe Val Gly Gly Asp Asp Phe 
    290                 295                 300                 


Lys Ser Gly Gln Thr Lys Val Lys Ser Val Leu Val Asp Phe Leu Ile 
305                 310                 315                 320 


Gly Ser Gly Leu Lys Thr Met Ser Ile Val Ser Tyr Asn His Leu Gly 
                325                 330                 335     


Asn Asn Asp Gly Glu Asn Leu Ser Ala Pro Leu Gln Phe Arg Ser Lys 
            340                 345                 350         


Glu Val Ser Lys Ser Asn Val Val Asp Asp Met Val Gln Ser Asn Pro 
        355                 360                 365             


Val Leu Tyr Thr Pro Gly Glu Glu Pro Asp His Cys Val Val Ile Lys 
    370                 375                 380                 


Tyr Val Pro Tyr Val Gly Asp Ser Lys Arg Ala Leu Asp Glu Tyr Thr 
385                 390                 395                 400 


Ser Glu Leu Met Leu Gly Gly Thr Asn Thr Leu Val Leu His Asn Thr 
                405                 410                 415     


Cys Glu Asp Ser Leu Leu Ala Ala Pro Ile Met Leu Asp Leu Ala Leu 
            420                 425                 430         


Leu Thr Glu Leu Cys Gln Arg Val Ser Phe Cys Thr Asp Met Asp Pro 
        435                 440                 445             


Glu Pro Gln Thr Phe His Pro Val Leu Ser Leu Leu Ser Phe Leu Phe 
    450                 455                 460                 


Lys Ala Pro Leu Val Pro Pro Gly Ser Pro Val Val Asn Ala Leu Phe 
465                 470                 475                 480 


Arg Gln Arg Ser Cys Ile Glu Asn Ile Leu Arg Ala Cys Val Gly Leu 
                485                 490                 495     


Pro Pro Gln Asn His Met Leu Leu Glu His Lys Met Glu Arg Pro Gly 
            500                 505                 510         


Pro Ser Leu Lys Arg Val Gly Pro Val Ala Ala Thr Tyr Pro Met Leu 
        515                 520                 525             


Asn Lys Lys Gly Pro Val Pro Ala Ala Thr Asn Gly Cys Thr Gly Asp 
    530                 535                 540                 


Ala Asn Gly His Leu Gln Glu Glu Pro Pro Met Pro Thr Thr 
545                 550                 555             


<210>  3796
<211>  854
<212>  PRT
<213>  homo sapiens

<400>  3796

Met Glu Arg Pro Tyr Thr Phe Lys Asp Phe Leu Leu Arg Pro Arg Ser 
1               5                   10                  15      


His Lys Ser Arg Val Lys Gly Phe Leu Arg Leu Lys Met Ala Tyr Met 
            20                  25                  30          


Pro Lys Asn Gly Gly Gln Asp Glu Glu Asn Ser Asp Gln Arg Asp Asp 
        35                  40                  45              


Met Glu His Gly Trp Glu Val Val Asp Ser Asn Asp Ser Ala Ser Gln 
    50                  55                  60                  


His Gln Glu Glu Leu Pro Pro Pro Pro Leu Pro Pro Gly Trp Glu Glu 
65                  70                  75                  80  


Lys Val Asp Asn Leu Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg 
                85                  90                  95      


Thr Thr Gln Trp His Arg Pro Ser Leu Met Asp Val Ser Ser Glu Ser 
            100                 105                 110         


Asp Asn Asn Ile Arg Gln Ile Asn Gln Glu Ala Ala His Arg Arg Phe 
        115                 120                 125             


Arg Ser Arg Arg His Ile Ser Glu Asp Leu Glu Pro Glu Pro Ser Glu 
    130                 135                 140                 


Gly Gly Asp Val Pro Glu Pro Trp Glu Thr Ile Ser Glu Glu Val Asn 
145                 150                 155                 160 


Ile Ala Gly Asp Ser Leu Gly Leu Ala Leu Pro Pro Pro Pro Ala Ser 
                165                 170                 175     


Pro Gly Ser Arg Thr Ser Pro Gln Glu Leu Ser Glu Glu Leu Ser Arg 
            180                 185                 190         


Arg Leu Gln Ile Thr Pro Asp Ser Asn Gly Glu Gln Phe Ser Ser Leu 
        195                 200                 205             


Ile Gln Arg Glu Pro Ser Ser Arg Leu Arg Ser Cys Ser Val Thr Asp 
    210                 215                 220                 


Ala Val Ala Glu Gln Gly His Leu Pro Pro Pro Ser Ala Pro Ala Gly 
225                 230                 235                 240 


Arg Ala Arg Ser Ser Thr Val Thr Gly Gly Glu Glu Pro Thr Pro Ser 
                245                 250                 255     


Val Ala Tyr Val His Thr Thr Pro Gly Leu Pro Ser Gly Trp Glu Glu 
            260                 265                 270         


Arg Lys Asp Ala Lys Gly Arg Thr Tyr Tyr Val Asn His Asn Asn Arg 
        275                 280                 285             


Thr Thr Thr Trp Thr Arg Pro Ile Met Gln Leu Ala Glu Asp Gly Ala 
    290                 295                 300                 


Ser Gly Ser Ala Thr Asn Ser Asn Asn His Leu Ile Glu Pro Gln Ile 
305                 310                 315                 320 


Arg Arg Pro Arg Ser Leu Ser Ser Pro Thr Val Thr Leu Ser Ala Pro 
                325                 330                 335     


Leu Glu Gly Ala Lys Asp Ser Pro Val Arg Arg Ala Val Lys Asp Thr 
            340                 345                 350         


Leu Ser Asn Pro Gln Ser Pro Gln Pro Ser Pro Tyr Asn Ser Pro Lys 
        355                 360                 365             


Pro Gln His Lys Val Thr Gln Ser Phe Leu Pro Pro Gly Trp Glu Met 
    370                 375                 380                 


Arg Ile Ala Pro Asn Gly Arg Pro Phe Phe Ile Asp His Asn Thr Lys 
385                 390                 395                 400 


Thr Thr Thr Trp Glu Asp Pro Arg Leu Lys Phe Pro Val His Met Arg 
                405                 410                 415     


Ser Lys Thr Ser Leu Asn Pro Asn Asp Leu Gly Pro Leu Pro Pro Gly 
            420                 425                 430         


Trp Glu Glu Arg Ile His Leu Asp Gly Arg Thr Phe Tyr Ile Asp His 
        435                 440                 445             


Asn Ser Lys Ile Thr Gln Trp Glu Asp Pro Arg Leu Gln Asn Pro Ala 
    450                 455                 460                 


Ile Thr Gly Pro Ala Val Pro Tyr Ser Arg Glu Phe Lys Gln Lys Tyr 
465                 470                 475                 480 


Asp Tyr Phe Arg Lys Lys Leu Lys Lys Pro Ala Asp Ile Pro Asn Arg 
                485                 490                 495     


Phe Glu Met Lys Leu His Arg Asn Asn Ile Phe Glu Glu Ser Tyr Arg 
            500                 505                 510         


Arg Ile Met Ser Val Lys Arg Pro Asp Val Leu Lys Ala Arg Leu Trp 
        515                 520                 525             


Ile Glu Phe Glu Ser Glu Lys Gly Leu Asp Tyr Gly Gly Val Ala Arg 
    530                 535                 540                 


Glu Trp Phe Phe Leu Leu Ser Lys Glu Met Phe Asn Pro Tyr Tyr Gly 
545                 550                 555                 560 


Leu Phe Glu Tyr Ser Ala Thr Asp Asn Tyr Thr Leu Gln Ile Asn Pro 
                565                 570                 575     


Asn Ser Gly Leu Cys Asn Glu Asp His Leu Ser Tyr Phe Thr Phe Ile 
            580                 585                 590         


Gly Arg Val Ala Gly Leu Ala Val Phe His Gly Lys Leu Leu Asp Gly 
        595                 600                 605             


Phe Phe Ile Arg Pro Phe Tyr Lys Met Met Leu Gly Lys Gln Ile Thr 
    610                 615                 620                 


Leu Asn Asp Met Glu Ser Val Asp Ser Glu Tyr Tyr Asn Ser Leu Lys 
625                 630                 635                 640 


Trp Ile Leu Glu Asn Asp Pro Thr Glu Leu Asp Leu Met Phe Cys Ile 
                645                 650                 655     


Asp Glu Glu Asn Phe Gly Gln Thr Tyr Gln Val Asp Leu Lys Pro Asn 
            660                 665                 670         


Gly Ser Glu Ile Met Val Thr Asn Glu Asn Lys Arg Glu Tyr Ile Asp 
        675                 680                 685             


Leu Val Ile Gln Trp Arg Phe Val Asn Arg Val Gln Lys Gln Met Asn 
    690                 695                 700                 


Ala Phe Leu Glu Gly Phe Thr Glu Leu Leu Pro Ile Asp Leu Ile Lys 
705                 710                 715                 720 


Ile Phe Asp Glu Asn Glu Leu Glu Leu Leu Met Cys Gly Leu Gly Asp 
                725                 730                 735     


Val Asp Val Asn Asp Trp Arg Gln His Ser Ile Tyr Lys Asn Gly Tyr 
            740                 745                 750         


Cys Pro Asn His Pro Val Ile Gln Trp Phe Trp Lys Ala Val Leu Leu 
        755                 760                 765             


Met Asp Ala Glu Lys Arg Ile Arg Leu Leu Gln Phe Val Thr Gly Thr 
    770                 775                 780                 


Ser Arg Val Pro Met Asn Gly Phe Ala Glu Leu Tyr Gly Ser Asn Gly 
785                 790                 795                 800 


Pro Gln Leu Phe Thr Ile Glu Gln Trp Gly Ser Pro Glu Lys Leu Pro 
                805                 810                 815     


Arg Ala His Thr Cys Phe Asn Arg Leu Asp Leu Pro Pro Tyr Glu Thr 
            820                 825                 830         


Phe Glu Asp Leu Arg Glu Lys Leu Leu Met Ala Val Glu Asn Ala Gln 
        835                 840                 845             


Gly Phe Glu Gly Val Asp 
    850                 


<210>  3797
<211>  359
<212>  PRT
<213>  homo sapiens

<400>  3797

Met Lys Ala Thr Ile Ile Leu Leu Leu Leu Ala Gln Val Ser Trp Ala 
1               5                   10                  15      


Gly Pro Phe Gln Gln Arg Gly Leu Phe Asp Phe Met Leu Glu Asp Glu 
            20                  25                  30          


Ala Ser Gly Ile Gly Pro Glu Val Pro Asp Asp Arg Asp Phe Glu Pro 
        35                  40                  45              


Ser Leu Gly Pro Val Cys Pro Phe Arg Cys Gln Cys His Leu Arg Val 
    50                  55                  60                  


Val Gln Cys Ser Asp Leu Gly Leu Asp Lys Val Pro Lys Asp Leu Pro 
65                  70                  75                  80  


Pro Asp Thr Thr Leu Leu Asp Leu Gln Asn Asn Lys Ile Thr Glu Ile 
                85                  90                  95      


Lys Asp Gly Asp Phe Lys Asn Leu Lys Asn Leu His Ala Leu Ile Leu 
            100                 105                 110         


Val Asn Asn Lys Ile Ser Lys Val Ser Pro Gly Ala Phe Thr Pro Leu 
        115                 120                 125             


Val Lys Leu Glu Arg Leu Tyr Leu Ser Lys Asn Gln Leu Lys Glu Leu 
    130                 135                 140                 


Pro Glu Lys Met Pro Lys Thr Leu Gln Glu Leu Arg Ala His Glu Asn 
145                 150                 155                 160 


Glu Ile Thr Lys Val Arg Lys Val Thr Phe Asn Gly Leu Asn Gln Met 
                165                 170                 175     


Ile Val Ile Glu Leu Gly Thr Asn Pro Leu Lys Ser Ser Gly Ile Glu 
            180                 185                 190         


Asn Gly Ala Phe Gln Gly Met Lys Lys Leu Ser Tyr Ile Arg Ile Ala 
        195                 200                 205             


Asp Thr Asn Ile Thr Ser Ile Pro Gln Gly Leu Pro Pro Ser Leu Thr 
    210                 215                 220                 


Glu Leu His Leu Asp Gly Asn Lys Ile Ser Arg Val Asp Ala Ala Ser 
225                 230                 235                 240 


Leu Lys Gly Leu Asn Asn Leu Ala Lys Leu Gly Leu Ser Phe Asn Ser 
                245                 250                 255     


Ile Ser Ala Val Asp Asn Gly Ser Leu Ala Asn Thr Pro His Leu Arg 
            260                 265                 270         


Glu Leu His Leu Asp Asn Asn Lys Leu Thr Arg Val Pro Gly Gly Leu 
        275                 280                 285             


Ala Glu His Lys Tyr Ile Gln Val Val Tyr Leu His Asn Asn Asn Ile 
    290                 295                 300                 


Ser Val Val Gly Ser Ser Asp Phe Cys Pro Pro Gly His Asn Thr Lys 
305                 310                 315                 320 


Lys Ala Ser Tyr Ser Gly Val Ser Leu Phe Ser Asn Pro Val Gln Tyr 
                325                 330                 335     


Trp Glu Ile Gln Pro Ser Thr Phe Arg Cys Val Tyr Val Arg Ser Ala 
            340                 345                 350         


Ile Gln Leu Gly Asn Tyr Lys 
        355                 


<210>  3798
<211>  625
<212>  PRT
<213>  homo sapiens

<400>  3798

Met Ala Asp Gln Arg Met Asp Ile Ser Ser Thr Ile Ser Asp Phe Met 
1               5                   10                  15      


Ser Pro Gly Pro Thr Asp Leu Leu Ser Ser Ser Leu Gly Thr Ser Gly 
            20                  25                  30          


Val Asp Cys Asn Arg Lys Arg Lys Gly Ser Ser Thr Asp Tyr Gln Glu 
        35                  40                  45              


Ser Met Asp Thr Asp Lys Asp Asp Pro His Gly Arg Leu Glu Tyr Thr 
    50                  55                  60                  


Glu His Gln Gly Arg Ile Lys Asn Ala Arg Glu Ala His Ser Gln Ile 
65                  70                  75                  80  


Glu Lys Arg Arg Arg Asp Lys Met Asn Ser Phe Ile Asp Glu Leu Ala 
                85                  90                  95      


Ser Leu Val Pro Thr Cys Asn Ala Met Ser Arg Lys Leu Asp Lys Leu 
            100                 105                 110         


Thr Val Leu Arg Met Ala Val Gln His Met Lys Thr Leu Arg Gly Ala 
        115                 120                 125             


Thr Asn Pro Tyr Thr Glu Ala Asn Tyr Lys Pro Thr Phe Leu Ser Asp 
    130                 135                 140                 


Asp Glu Leu Lys His Leu Ile Leu Arg Ala Ala Asp Gly Phe Leu Phe 
145                 150                 155                 160 


Val Val Gly Cys Asp Arg Gly Lys Ile Leu Phe Val Ser Glu Ser Val 
                165                 170                 175     


Phe Lys Ile Leu Asn Tyr Ser Gln Asn Asp Leu Ile Gly Gln Ser Leu 
            180                 185                 190         


Phe Asp Tyr Leu His Pro Lys Asp Ile Ala Lys Val Lys Glu Gln Leu 
        195                 200                 205             


Ser Ser Ser Asp Thr Ala Pro Arg Glu Arg Leu Ile Asp Ala Lys Thr 
    210                 215                 220                 


Gly Leu Pro Val Lys Thr Asp Ile Thr Pro Gly Pro Ser Arg Leu Cys 
225                 230                 235                 240 


Ser Gly Ala Arg Arg Ser Phe Phe Cys Arg Met Lys Cys Asn Arg Pro 
                245                 250                 255     


Ser Val Lys Val Glu Asp Lys Asp Phe Pro Ser Thr Cys Ser Lys Lys 
            260                 265                 270         


Lys Asp Arg Lys Ser Phe Cys Thr Ile His Ser Thr Gly Tyr Leu Lys 
        275                 280                 285             


Ser Trp Pro Pro Thr Lys Met Gly Leu Asp Glu Asp Asn Glu Pro Asp 
    290                 295                 300                 


Asn Glu Gly Cys Asn Leu Ser Cys Leu Val Ala Ile Gly Arg Leu His 
305                 310                 315                 320 


Ser His Val Val Pro Gln Pro Val Asn Gly Glu Ile Arg Val Lys Ser 
                325                 330                 335     


Met Glu Tyr Val Ser Arg His Ala Ile Asp Gly Lys Phe Val Phe Val 
            340                 345                 350         


Asp Gln Arg Ala Thr Ala Ile Leu Ala Tyr Leu Pro Gln Glu Leu Leu 
        355                 360                 365             


Gly Thr Ser Cys Tyr Glu Tyr Phe His Gln Asp Asp Ile Gly His Leu 
    370                 375                 380                 


Ala Glu Cys His Arg Gln Val Leu Gln Thr Arg Glu Lys Ile Thr Thr 
385                 390                 395                 400 


Asn Cys Tyr Lys Phe Lys Ile Lys Asp Gly Ser Phe Ile Thr Leu Arg 
                405                 410                 415     


Ser Arg Trp Phe Ser Phe Met Asn Pro Trp Thr Lys Glu Val Glu Tyr 
            420                 425                 430         


Ile Val Ser Thr Asn Thr Val Val Leu Ala Asn Val Leu Glu Gly Gly 
        435                 440                 445             


Asp Pro Thr Phe Pro Gln Leu Thr Ala Ser Pro His Ser Met Asp Ser 
    450                 455                 460                 


Met Leu Pro Ser Gly Glu Gly Gly Pro Lys Arg Thr His Pro Thr Val 
465                 470                 475                 480 


Pro Gly Ile Pro Gly Gly Thr Arg Ala Gly Ala Gly Lys Ile Gly Arg 
                485                 490                 495     


Met Ile Ala Glu Glu Ile Met Glu Ile His Arg Ile Arg Gly Ser Ser 
            500                 505                 510         


Pro Ser Ser Cys Gly Ser Ser Pro Leu Asn Ile Thr Ser Thr Pro Pro 
        515                 520                 525             


Pro Asp Ala Ser Ser Pro Gly Gly Lys Lys Ile Leu Asn Gly Gly Thr 
    530                 535                 540                 


Pro Asp Ile Pro Ser Ser Gly Leu Leu Ser Gly Gln Ala Gln Glu Asn 
545                 550                 555                 560 


Pro Gly Tyr Pro Tyr Ser Asp Ser Ser Ser Ile Leu Gly Glu Asn Pro 
                565                 570                 575     


His Ile Gly Ile Asp Met Ile Asp Asn Asp Gln Gly Ser Ser Ser Pro 
            580                 585                 590         


Ser Asn Asp Glu Ala Ala Met Ala Val Ile Met Ser Leu Leu Glu Ala 
        595                 600                 605             


Asp Ala Gly Leu Gly Gly Pro Val Asp Phe Ser Asp Leu Pro Trp Pro 
    610                 615                 620                 


Leu 
625 


<210>  3799
<211>  322
<212>  PRT
<213>  homo sapiens

<400>  3799

Met Pro Val Thr Val Thr Arg Thr Thr Ile Thr Thr Thr Thr Thr Ser 
1               5                   10                  15      


Ser Ser Gly Leu Gly Ser Pro Met Ile Val Gly Ser Pro Arg Ala Leu 
            20                  25                  30          


Thr Gln Pro Leu Gly Leu Leu Arg Leu Leu Gln Leu Val Ser Thr Cys 
        35                  40                  45              


Val Ala Phe Ser Leu Val Ala Ser Val Gly Ala Trp Thr Gly Ser Met 
    50                  55                  60                  


Gly Asn Trp Ser Met Phe Thr Trp Cys Phe Cys Phe Ser Val Thr Leu 
65                  70                  75                  80  


Ile Ile Leu Ile Val Glu Leu Cys Gly Leu Gln Ala Arg Phe Pro Leu 
                85                  90                  95      


Ser Trp Arg Asn Phe Pro Ile Thr Phe Ala Cys Tyr Ala Ala Leu Phe 
            100                 105                 110         


Cys Leu Ser Ala Ser Ile Ile Tyr Pro Thr Thr Tyr Val Gln Phe Leu 
        115                 120                 125             


Ser His Gly Arg Ser Arg Asp His Ala Ile Ala Ala Thr Phe Phe Ser 
    130                 135                 140                 


Cys Ile Ala Cys Val Ala Tyr Ala Thr Glu Val Ala Trp Thr Arg Ala 
145                 150                 155                 160 


Arg Pro Gly Glu Ile Thr Gly Tyr Met Ala Thr Val Pro Gly Leu Leu 
                165                 170                 175     


Lys Val Leu Glu Thr Phe Val Ala Cys Ile Ile Phe Ala Phe Ile Ser 
            180                 185                 190         


Asp Pro Asn Leu Tyr Gln His Gln Pro Ala Leu Glu Trp Cys Val Ala 
        195                 200                 205             


Val Tyr Ala Ile Cys Phe Ile Leu Ala Ala Ile Ala Ile Leu Leu Asn 
    210                 215                 220                 


Leu Gly Glu Cys Thr Asn Val Leu Pro Ile Pro Phe Pro Ser Phe Leu 
225                 230                 235                 240 


Ser Gly Leu Ala Leu Leu Ser Val Leu Leu Tyr Ala Thr Ala Leu Val 
                245                 250                 255     


Leu Trp Pro Leu Tyr Gln Phe Asp Glu Lys Tyr Gly Gly Gln Pro Arg 
            260                 265                 270         


Arg Ser Arg Asp Val Ser Cys Ser Arg Ser His Ala Tyr Tyr Val Cys 
        275                 280                 285             


Ala Trp Asp Arg Arg Leu Ala Val Ala Ile Leu Thr Ala Ile Asn Leu 
    290                 295                 300                 


Leu Ala Tyr Val Ala Asp Leu Val His Ser Ala His Leu Val Phe Val 
305                 310                 315                 320 


Lys Val 
        


<210>  3800
<211>  187
<212>  PRT
<213>  homo sapiens

<400>  3800

Met Val Gly Ser Leu Asn Cys Ile Val Ala Val Ser Gln Asn Met Gly 
1               5                   10                  15      


Ile Gly Lys Asn Gly Asp Leu Pro Trp Pro Pro Leu Arg Asn Glu Phe 
            20                  25                  30          


Arg Tyr Phe Gln Arg Met Thr Thr Thr Ser Ser Val Glu Gly Lys Gln 
        35                  40                  45              


Asn Leu Val Ile Met Gly Lys Lys Thr Trp Phe Ser Ile Pro Glu Lys 
    50                  55                  60                  


Asn Arg Pro Leu Lys Gly Arg Ile Asn Leu Val Leu Ser Arg Glu Leu 
65                  70                  75                  80  


Lys Glu Pro Pro Gln Gly Ala His Phe Leu Ser Arg Ser Leu Asp Asp 
                85                  90                  95      


Ala Leu Lys Leu Thr Glu Gln Pro Glu Leu Ala Asn Lys Val Asp Met 
            100                 105                 110         


Val Trp Ile Val Gly Gly Ser Ser Val Tyr Lys Glu Ala Met Asn His 
        115                 120                 125             


Pro Gly His Leu Lys Leu Phe Val Thr Arg Ile Met Gln Asp Phe Glu 
    130                 135                 140                 


Ser Asp Thr Phe Phe Pro Glu Ile Asp Leu Glu Lys Tyr Lys Leu Leu 
145                 150                 155                 160 


Pro Glu Tyr Pro Gly Val Leu Ser Asp Val Gln Glu Glu Lys Gly Ile 
                165                 170                 175     


Lys Tyr Lys Phe Glu Val Tyr Glu Lys Asn Asp 
            180                 185         


<210>  3801
<211>  569
<212>  PRT
<213>  homo sapiens

<400>  3801

Met Pro Ser Ser Leu Phe Ala Asp Leu Glu Arg Asn Gly Ser Gly Gly 
1               5                   10                  15      


Gly Gly Gly Gly Ser Ser Gly Gly Gly Glu Thr Leu Asp Asp Gln Arg 
            20                  25                  30          


Ala Leu Gln Leu Ala Leu Asp Gln Leu Ser Leu Leu Gly Leu Asp Ser 
        35                  40                  45              


Asp Glu Gly Ala Ser Leu Tyr Asp Ser Glu Pro Arg Lys Lys Ser Val 
    50                  55                  60                  


Asn Met Thr Glu Cys Val Pro Val Pro Ser Ser Glu His Val Ala Glu 
65                  70                  75                  80  


Ile Val Gly Arg Gln Gly Cys Lys Ile Lys Ala Leu Arg Ala Lys Thr 
                85                  90                  95      


Asn Thr Tyr Ile Lys Thr Pro Val Arg Gly Glu Glu Pro Val Phe Val 
            100                 105                 110         


Val Thr Gly Arg Lys Glu Asp Val Ala Met Ala Arg Arg Glu Ile Ile 
        115                 120                 125             


Ser Ala Ala Glu His Phe Ser Met Ile Arg Ala Ser Arg Asn Lys Asn 
    130                 135                 140                 


Thr Ala Leu Asn Gly Ala Val Pro Gly Pro Pro Asn Leu Pro Gly Gln 
145                 150                 155                 160 


Thr Thr Ile Gln Val Arg Val Pro Tyr Arg Val Val Gly Leu Val Val 
                165                 170                 175     


Gly Pro Lys Gly Ala Thr Ile Lys Arg Ile Gln Gln Gln Thr His Thr 
            180                 185                 190         


Tyr Ile Val Thr Pro Ser Arg Asp Lys Glu Pro Val Phe Glu Val Thr 
        195                 200                 205             


Gly Met Pro Glu Asn Val Asp Arg Ala Arg Glu Glu Ile Glu Ala His 
    210                 215                 220                 


Ile Ala Leu Arg Thr Gly Gly Ile Ile Glu Leu Thr Asp Glu Asn Asp 
225                 230                 235                 240 


Phe His Ala Asn Gly Thr Asp Val Gly Phe Asp Leu His His Gly Ser 
                245                 250                 255     


Gly Gly Ser Gly Pro Gly Ser Leu Trp Ser Lys Pro Thr Pro Ser Ile 
            260                 265                 270         


Thr Pro Thr Pro Gly Arg Lys Pro Phe Ser Ser Tyr Arg Asn Asp Ser 
        275                 280                 285             


Ser Ser Ser Leu Gly Ser Ala Ser Thr Asp Ser Tyr Phe Gly Gly Gly 
    290                 295                 300                 


Thr Ser Ser Ser Ala Ala Ala Thr Gln Arg Leu Ala Asp Tyr Ser Pro 
305                 310                 315                 320 


Pro Ser Pro Ala Leu Ser Phe Ala His Asn Gly Asn Asn Asn Asn Asn 
                325                 330                 335     


Gly Asn Gly Tyr Thr Tyr Thr Ala Gly Gly Glu Ala Ser Val Pro Ser 
            340                 345                 350         


Pro Asp Gly Cys Pro Glu Leu Gln Pro Thr Phe Asp Pro Ala Pro Ala 
        355                 360                 365             


Pro Pro Pro Gly Ala Pro Leu Ile Trp Ala Gln Phe Glu Arg Ser Pro 
    370                 375                 380                 


Gly Gly Gly Pro Ala Ala Pro Val Ser Ser Ser Cys Ser Ser Ser Ala 
385                 390                 395                 400 


Ser Ser Ser Ala Ser Ser Ser Ser Val Val Phe Pro Gly Gly Gly Ala 
                405                 410                 415     


Ser Ala Pro Ser Asn Ala Asn Leu Gly Leu Leu Val His Arg Arg Leu 
            420                 425                 430         


His Pro Gly Thr Ser Cys Pro Arg Leu Ser Pro Pro Leu His Met Ala 
        435                 440                 445             


Pro Gly Ala Gly Glu His His Leu Ala Arg Arg Val Arg Ser Asp Pro 
    450                 455                 460                 


Gly Gly Gly Gly Leu Ala Tyr Ala Ala Tyr Ala Asn Gly Leu Gly Ala 
465                 470                 475                 480 


Gln Leu Pro Gly Leu Gln Pro Ser Asp Thr Ser Gly Ser Ser Ser Ser 
                485                 490                 495     


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Gly Leu Arg Arg 
            500                 505                 510         


Lys Gly Ser Arg Asp Cys Ser Val Cys Phe Glu Ser Glu Val Ile Ala 
        515                 520                 525             


Ala Leu Val Pro Cys Gly His Asn Leu Phe Cys Met Glu Cys Ala Asn 
    530                 535                 540                 


Arg Ile Cys Glu Lys Ser Glu Pro Glu Cys Pro Val Cys His Thr Ala 
545                 550                 555                 560 


Val Thr Gln Ala Ile Arg Ile Phe Ser 
                565                 


<210>  3802
<211>  1367
<212>  PRT
<213>  homo sapiens

<400>  3802

Met Lys Ser Gly Ser Gly Gly Gly Ser Pro Thr Ser Leu Trp Gly Leu 
1               5                   10                  15      


Leu Phe Leu Ser Ala Ala Leu Ser Leu Trp Pro Thr Ser Gly Glu Ile 
            20                  25                  30          


Cys Gly Pro Gly Ile Asp Ile Arg Asn Asp Tyr Gln Gln Leu Lys Arg 
        35                  40                  45              


Leu Glu Asn Cys Thr Val Ile Glu Gly Tyr Leu His Ile Leu Leu Ile 
    50                  55                  60                  


Ser Lys Ala Glu Asp Tyr Arg Ser Tyr Arg Phe Pro Lys Leu Thr Val 
65                  70                  75                  80  


Ile Thr Glu Tyr Leu Leu Leu Phe Arg Val Ala Gly Leu Glu Ser Leu 
                85                  90                  95      


Gly Asp Leu Phe Pro Asn Leu Thr Val Ile Arg Gly Trp Lys Leu Phe 
            100                 105                 110         


Tyr Asn Tyr Ala Leu Val Ile Phe Glu Met Thr Asn Leu Lys Asp Ile 
        115                 120                 125             


Gly Leu Tyr Asn Leu Arg Asn Ile Thr Arg Gly Ala Ile Arg Ile Glu 
    130                 135                 140                 


Lys Asn Ala Asp Leu Cys Tyr Leu Ser Thr Val Asp Trp Ser Leu Ile 
145                 150                 155                 160 


Leu Asp Ala Val Ser Asn Asn Tyr Ile Val Gly Asn Lys Pro Pro Lys 
                165                 170                 175     


Glu Cys Gly Asp Leu Cys Pro Gly Thr Met Glu Glu Lys Pro Met Cys 
            180                 185                 190         


Glu Lys Thr Thr Ile Asn Asn Glu Tyr Asn Tyr Arg Cys Trp Thr Thr 
        195                 200                 205             


Asn Arg Cys Gln Lys Met Cys Pro Ser Thr Cys Gly Lys Arg Ala Cys 
    210                 215                 220                 


Thr Glu Asn Asn Glu Cys Cys His Pro Glu Cys Leu Gly Ser Cys Ser 
225                 230                 235                 240 


Ala Pro Asp Asn Asp Thr Ala Cys Val Ala Cys Arg His Tyr Tyr Tyr 
                245                 250                 255     


Ala Gly Val Cys Val Pro Ala Cys Pro Pro Asn Thr Tyr Arg Phe Glu 
            260                 265                 270         


Gly Trp Arg Cys Val Asp Arg Asp Phe Cys Ala Asn Ile Leu Ser Ala 
        275                 280                 285             


Glu Ser Ser Asp Ser Glu Gly Phe Val Ile His Asp Gly Glu Cys Met 
    290                 295                 300                 


Gln Glu Cys Pro Ser Gly Phe Ile Arg Asn Gly Ser Gln Ser Met Tyr 
305                 310                 315                 320 


Cys Ile Pro Cys Glu Gly Pro Cys Pro Lys Val Cys Glu Glu Glu Lys 
                325                 330                 335     


Lys Thr Lys Thr Ile Asp Ser Val Thr Ser Ala Gln Met Leu Gln Gly 
            340                 345                 350         


Cys Thr Ile Phe Lys Gly Asn Leu Leu Ile Asn Ile Arg Arg Gly Asn 
        355                 360                 365             


Asn Ile Ala Ser Glu Leu Glu Asn Phe Met Gly Leu Ile Glu Val Val 
    370                 375                 380                 


Thr Gly Tyr Val Lys Ile Arg His Ser His Ala Leu Val Ser Leu Ser 
385                 390                 395                 400 


Phe Leu Lys Asn Leu Arg Leu Ile Leu Gly Glu Glu Gln Leu Glu Gly 
                405                 410                 415     


Asn Tyr Ser Phe Tyr Val Leu Asp Asn Gln Asn Leu Gln Gln Leu Trp 
            420                 425                 430         


Asp Trp Asp His Arg Asn Leu Thr Ile Lys Ala Gly Lys Met Tyr Phe 
        435                 440                 445             


Ala Phe Asn Pro Lys Leu Cys Val Ser Glu Ile Tyr Arg Met Glu Glu 
    450                 455                 460                 


Val Thr Gly Thr Lys Gly Arg Gln Ser Lys Gly Asp Ile Asn Thr Arg 
465                 470                 475                 480 


Asn Asn Gly Glu Arg Ala Ser Cys Glu Ser Asp Val Leu His Phe Thr 
                485                 490                 495     


Ser Thr Thr Thr Ser Lys Asn Arg Ile Ile Ile Thr Trp His Arg Tyr 
            500                 505                 510         


Arg Pro Pro Asp Tyr Arg Asp Leu Ile Ser Phe Thr Val Tyr Tyr Lys 
        515                 520                 525             


Glu Ala Pro Phe Lys Asn Val Thr Glu Tyr Asp Gly Gln Asp Ala Cys 
    530                 535                 540                 


Gly Ser Asn Ser Trp Asn Met Val Asp Val Asp Leu Pro Pro Asn Lys 
545                 550                 555                 560 


Asp Val Glu Pro Gly Ile Leu Leu His Gly Leu Lys Pro Trp Thr Gln 
                565                 570                 575     


Tyr Ala Val Tyr Val Lys Ala Val Thr Leu Thr Met Val Glu Asn Asp 
            580                 585                 590         


His Ile Arg Gly Ala Lys Ser Glu Ile Leu Tyr Ile Arg Thr Asn Ala 
        595                 600                 605             


Ser Val Pro Ser Ile Pro Leu Asp Val Leu Ser Ala Ser Asn Ser Ser 
    610                 615                 620                 


Ser Gln Leu Ile Val Lys Trp Asn Pro Pro Ser Leu Pro Asn Gly Asn 
625                 630                 635                 640 


Leu Ser Tyr Tyr Ile Val Arg Trp Gln Arg Gln Pro Gln Asp Gly Tyr 
                645                 650                 655     


Leu Tyr Arg His Asn Tyr Cys Ser Lys Asp Lys Ile Pro Ile Arg Lys 
            660                 665                 670         


Tyr Ala Asp Gly Thr Ile Asp Ile Glu Glu Val Thr Glu Asn Pro Lys 
        675                 680                 685             


Thr Glu Val Cys Gly Gly Glu Lys Gly Pro Cys Cys Ala Cys Pro Lys 
    690                 695                 700                 


Thr Glu Ala Glu Lys Gln Ala Glu Lys Glu Glu Ala Glu Tyr Arg Lys 
705                 710                 715                 720 


Val Phe Glu Asn Phe Leu His Asn Ser Ile Phe Val Pro Arg Pro Glu 
                725                 730                 735     


Arg Lys Arg Arg Asp Val Met Gln Val Ala Asn Thr Thr Met Ser Ser 
            740                 745                 750         


Arg Ser Arg Asn Thr Thr Ala Ala Asp Thr Tyr Asn Ile Thr Asp Pro 
        755                 760                 765             


Glu Glu Leu Glu Thr Glu Tyr Pro Phe Phe Glu Ser Arg Val Asp Asn 
    770                 775                 780                 


Lys Glu Arg Thr Val Ile Ser Asn Leu Arg Pro Phe Thr Leu Tyr Arg 
785                 790                 795                 800 


Ile Asp Ile His Ser Cys Asn His Glu Ala Glu Lys Leu Gly Cys Ser 
                805                 810                 815     


Ala Ser Asn Phe Val Phe Ala Arg Thr Met Pro Ala Glu Gly Ala Asp 
            820                 825                 830         


Asp Ile Pro Gly Pro Val Thr Trp Glu Pro Arg Pro Glu Asn Ser Ile 
        835                 840                 845             


Phe Leu Lys Trp Pro Glu Pro Glu Asn Pro Asn Gly Leu Ile Leu Met 
    850                 855                 860                 


Tyr Glu Ile Lys Tyr Gly Ser Gln Val Glu Asp Gln Arg Glu Cys Val 
865                 870                 875                 880 


Ser Arg Gln Glu Tyr Arg Lys Tyr Gly Gly Ala Lys Leu Asn Arg Leu 
                885                 890                 895     


Asn Pro Gly Asn Tyr Thr Ala Arg Ile Gln Ala Thr Ser Leu Ser Gly 
            900                 905                 910         


Asn Gly Ser Trp Thr Asp Pro Val Phe Phe Tyr Val Gln Ala Lys Thr 
        915                 920                 925             


Gly Tyr Glu Asn Phe Ile His Leu Ile Ile Ala Leu Pro Val Ala Val 
    930                 935                 940                 


Leu Leu Ile Val Gly Gly Leu Val Ile Met Leu Tyr Val Phe His Arg 
945                 950                 955                 960 


Lys Arg Asn Asn Ser Arg Leu Gly Asn Gly Val Leu Tyr Ala Ser Val 
                965                 970                 975     


Asn Pro Glu Tyr Phe Ser Ala Ala Asp Val Tyr Val Pro Asp Glu Trp 
            980                 985                 990         


Glu Val Ala Arg Glu Lys Ile Thr  Met Ser Arg Glu Leu  Gly Gln Gly 
        995                 1000                 1005             


Ser Phe  Gly Met Val Tyr Glu  Gly Val Ala Lys Gly  Val Val Lys 
    1010                 1015                 1020             


Asp Glu  Pro Glu Thr Arg Val  Ala Ile Lys Thr Val  Asn Glu Ala 
    1025                 1030                 1035             


Ala Ser  Met Arg Glu Arg Ile  Glu Phe Leu Asn Glu  Ala Ser Val 
    1040                 1045                 1050             


Met Lys  Glu Phe Asn Cys His  His Val Val Arg Leu  Leu Gly Val 
    1055                 1060                 1065             


Val Ser  Gln Gly Gln Pro Thr  Leu Val Ile Met Glu  Leu Met Thr 
    1070                 1075                 1080             


Arg Gly  Asp Leu Lys Ser Tyr  Leu Arg Ser Leu Arg  Pro Glu Met 
    1085                 1090                 1095             


Glu Asn  Asn Pro Val Leu Ala  Pro Pro Ser Leu Ser  Lys Met Ile 
    1100                 1105                 1110             


Gln Met  Ala Gly Glu Ile Ala  Asp Gly Met Ala Tyr  Leu Asn Ala 
    1115                 1120                 1125             


Asn Lys  Phe Val His Arg Asp  Leu Ala Ala Arg Asn  Cys Met Val 
    1130                 1135                 1140             


Ala Glu  Asp Phe Thr Val Lys  Ile Gly Asp Phe Gly  Met Thr Arg 
    1145                 1150                 1155             


Asp Ile  Tyr Glu Thr Asp Tyr  Tyr Arg Lys Gly Gly  Lys Gly Leu 
    1160                 1165                 1170             


Leu Pro  Val Arg Trp Met Ser  Pro Glu Ser Leu Lys  Asp Gly Val 
    1175                 1180                 1185             


Phe Thr  Thr Tyr Ser Asp Val  Trp Ser Phe Gly Val  Val Leu Trp 
    1190                 1195                 1200             


Glu Ile  Ala Thr Leu Ala Glu  Gln Pro Tyr Gln Gly  Leu Ser Asn 
    1205                 1210                 1215             


Glu Gln  Val Leu Arg Phe Val  Met Glu Gly Gly Leu  Leu Asp Lys 
    1220                 1225                 1230             


Pro Asp  Asn Cys Pro Asp Met  Leu Phe Glu Leu Met  Arg Met Cys 
    1235                 1240                 1245             


Trp Gln  Tyr Asn Pro Lys Met  Arg Pro Ser Phe Leu  Glu Ile Ile 
    1250                 1255                 1260             


Ser Ser  Ile Lys Glu Glu Met  Glu Pro Gly Phe Arg  Glu Val Ser 
    1265                 1270                 1275             


Phe Tyr  Tyr Ser Glu Glu Asn  Lys Leu Pro Glu Pro  Glu Glu Leu 
    1280                 1285                 1290             


Asp Leu  Glu Pro Glu Asn Met  Glu Ser Val Pro Leu  Asp Pro Ser 
    1295                 1300                 1305             


Ala Ser  Ser Ser Ser Leu Pro  Leu Pro Asp Arg His  Ser Gly His 
    1310                 1315                 1320             


Lys Ala  Glu Asn Gly Pro Gly  Pro Gly Val Leu Val  Leu Arg Ala 
    1325                 1330                 1335             


Ser Phe  Asp Glu Arg Gln Pro  Tyr Ala His Met Asn  Gly Gly Arg 
    1340                 1345                 1350             


Lys Asn  Glu Arg Ala Leu Pro  Leu Pro Gln Ser Ser  Thr Cys 
    1355                 1360                 1365         


<210>  3803
<211>  625
<212>  PRT
<213>  homo sapiens

<400>  3803

Met Ala Asp Gln Arg Met Asp Ile Ser Ser Thr Ile Ser Asp Phe Met 
1               5                   10                  15      


Ser Pro Gly Pro Thr Asp Leu Leu Ser Ser Ser Leu Gly Thr Ser Gly 
            20                  25                  30          


Val Asp Cys Asn Arg Lys Arg Lys Gly Ser Ser Thr Asp Tyr Gln Glu 
        35                  40                  45              


Ser Met Asp Thr Asp Lys Asp Asp Pro His Gly Arg Leu Glu Tyr Thr 
    50                  55                  60                  


Glu His Gln Gly Arg Ile Lys Asn Ala Arg Glu Ala His Ser Gln Ile 
65                  70                  75                  80  


Glu Lys Arg Arg Arg Asp Lys Met Asn Ser Phe Ile Asp Glu Leu Ala 
                85                  90                  95      


Ser Leu Val Pro Thr Cys Asn Ala Met Ser Arg Lys Leu Asp Lys Leu 
            100                 105                 110         


Thr Val Leu Arg Met Ala Val Gln His Met Lys Thr Leu Arg Gly Ala 
        115                 120                 125             


Thr Asn Pro Tyr Thr Glu Ala Asn Tyr Lys Pro Thr Phe Leu Ser Asp 
    130                 135                 140                 


Asp Glu Leu Lys His Leu Ile Leu Arg Ala Ala Asp Gly Phe Leu Phe 
145                 150                 155                 160 


Val Val Gly Cys Asp Arg Gly Lys Ile Leu Phe Val Ser Glu Ser Val 
                165                 170                 175     


Phe Lys Ile Leu Asn Tyr Ser Gln Asn Asp Leu Ile Gly Gln Ser Leu 
            180                 185                 190         


Phe Asp Tyr Leu His Pro Lys Asp Ile Ala Lys Val Lys Glu Gln Leu 
        195                 200                 205             


Ser Ser Ser Asp Thr Ala Pro Arg Glu Arg Leu Ile Asp Ala Lys Thr 
    210                 215                 220                 


Gly Leu Pro Val Lys Thr Asp Ile Thr Pro Gly Pro Ser Arg Leu Cys 
225                 230                 235                 240 


Ser Gly Ala Arg Arg Ser Phe Phe Cys Arg Met Lys Cys Asn Arg Pro 
                245                 250                 255     


Ser Val Lys Val Glu Asp Lys Asp Phe Pro Ser Thr Cys Ser Lys Lys 
            260                 265                 270         


Lys Asp Arg Lys Ser Phe Cys Thr Ile His Ser Thr Gly Tyr Leu Lys 
        275                 280                 285             


Ser Trp Pro Pro Thr Lys Met Gly Leu Asp Glu Asp Asn Glu Pro Asp 
    290                 295                 300                 


Asn Glu Gly Cys Asn Leu Ser Cys Leu Val Ala Ile Gly Arg Leu His 
305                 310                 315                 320 


Ser His Val Val Pro Gln Pro Val Asn Gly Glu Ile Arg Val Lys Ser 
                325                 330                 335     


Met Glu Tyr Val Ser Arg His Ala Ile Asp Gly Lys Phe Val Phe Val 
            340                 345                 350         


Asp Gln Arg Ala Thr Ala Ile Leu Ala Tyr Leu Pro Gln Glu Leu Leu 
        355                 360                 365             


Gly Thr Ser Cys Tyr Glu Tyr Phe His Gln Asp Asp Ile Gly His Leu 
    370                 375                 380                 


Ala Glu Cys His Arg Gln Val Leu Gln Thr Arg Glu Lys Ile Thr Thr 
385                 390                 395                 400 


Asn Cys Tyr Lys Phe Lys Ile Lys Asp Gly Ser Phe Ile Thr Leu Arg 
                405                 410                 415     


Ser Arg Trp Phe Ser Phe Met Asn Pro Trp Thr Lys Glu Val Glu Tyr 
            420                 425                 430         


Ile Val Ser Thr Asn Thr Val Val Leu Ala Asn Val Leu Glu Gly Gly 
        435                 440                 445             


Asp Pro Thr Phe Pro Gln Leu Thr Ala Ser Pro His Ser Met Asp Ser 
    450                 455                 460                 


Met Leu Pro Ser Gly Glu Gly Gly Pro Lys Arg Thr His Pro Thr Val 
465                 470                 475                 480 


Pro Gly Ile Pro Gly Gly Thr Arg Ala Gly Ala Gly Lys Ile Gly Arg 
                485                 490                 495     


Met Ile Ala Glu Glu Ile Met Glu Ile His Arg Ile Arg Gly Ser Ser 
            500                 505                 510         


Pro Ser Ser Cys Gly Ser Ser Pro Leu Asn Ile Thr Ser Thr Pro Pro 
        515                 520                 525             


Pro Asp Ala Ser Ser Pro Gly Gly Lys Lys Ile Leu Asn Gly Gly Thr 
    530                 535                 540                 


Pro Asp Ile Pro Ser Ser Gly Leu Leu Ser Gly Gln Ala Gln Glu Asn 
545                 550                 555                 560 


Pro Gly Tyr Pro Tyr Ser Asp Ser Ser Ser Ile Leu Gly Glu Asn Pro 
                565                 570                 575     


His Ile Gly Ile Asp Met Ile Asp Asn Asp Gln Gly Ser Ser Ser Pro 
            580                 585                 590         


Ser Asn Asp Glu Ala Ala Met Ala Val Ile Met Ser Leu Leu Glu Ala 
        595                 600                 605             


Asp Ala Gly Leu Gly Gly Pro Val Asp Phe Ser Asp Leu Pro Trp Pro 
    610                 615                 620                 


Leu 
625 


<210>  3804
<211>  1686
<212>  PRT
<213>  homo sapiens

<400>  3804

Met Ala Gln Ile Ser Ser Asn Ser Gly Phe Lys Glu Cys Pro Ser Ser 
1               5                   10                  15      


His Pro Glu Pro Thr Arg Ala Lys Asp Val Asp Lys Glu Glu Ala Leu 
            20                  25                  30          


Gln Met Glu Ala Glu Ala Leu Ala Lys Leu Gln Lys Asp Arg Gln Val 
        35                  40                  45              


Thr Asp Asn Gln Arg Gly Phe Glu Leu Ser Ser Ser Thr Arg Lys Lys 
    50                  55                  60                  


Ala Gln Val Tyr Asn Lys Gln Asp Tyr Asp Leu Met Val Phe Pro Glu 
65                  70                  75                  80  


Ser Asp Ser Gln Lys Arg Ala Leu Asp Ile Asp Val Glu Lys Leu Thr 
                85                  90                  95      


Gln Ala Glu Leu Glu Lys Leu Leu Leu Asp Asp Ser Phe Glu Thr Lys 
            100                 105                 110         


Lys Thr Pro Val Leu Pro Val Thr Pro Ile Leu Ser Pro Ser Phe Ser 
        115                 120                 125             


Ala Gln Leu Tyr Phe Arg Pro Thr Ile Gln Arg Gly Gln Trp Pro Pro 
    130                 135                 140                 


Gly Leu Pro Gly Pro Ser Thr Tyr Ala Leu Pro Ser Ile Tyr Pro Ser 
145                 150                 155                 160 


Thr Tyr Ser Lys Gln Ala Ala Phe Gln Asn Gly Phe Asn Pro Arg Met 
                165                 170                 175     


Pro Thr Phe Pro Ser Thr Glu Pro Ile Tyr Leu Ser Leu Pro Gly Gln 
            180                 185                 190         


Ser Pro Tyr Phe Ser Tyr Pro Leu Thr Pro Ala Thr Pro Phe His Pro 
        195                 200                 205             


Gln Gly Ser Leu Pro Ile Tyr Arg Pro Val Val Ser Thr Asp Met Ala 
    210                 215                 220                 


Lys Leu Phe Asp Lys Ile Ala Ser Thr Ser Glu Phe Leu Lys Asn Gly 
225                 230                 235                 240 


Lys Ala Arg Thr Asp Leu Glu Ile Thr Asp Ser Lys Val Ser Asn Leu 
                245                 250                 255     


Gln Val Ser Pro Lys Ser Glu Asp Ile Ser Lys Phe Asp Trp Leu Asp 
            260                 265                 270         


Leu Asp Pro Leu Ser Lys Pro Lys Val Asp Asn Val Glu Val Leu Asp 
        275                 280                 285             


His Glu Glu Glu Lys Asn Val Ser Ser Leu Leu Ala Lys Asp Pro Trp 
    290                 295                 300                 


Asp Ala Val Leu Leu Glu Glu Arg Ser Thr Ala Asn Cys His Leu Glu 
305                 310                 315                 320 


Arg Lys Val Asn Gly Lys Ser Leu Ser Val Ala Thr Val Thr Arg Ser 
                325                 330                 335     


Gln Ser Leu Asn Ile Arg Thr Thr Gln Leu Ala Lys Ala Gln Gly His 
            340                 345                 350         


Ile Ser Gln Lys Asp Pro Asn Gly Thr Ser Ser Leu Pro Thr Gly Ser 
        355                 360                 365             


Ser Leu Leu Gln Glu Val Glu Val Gln Asn Glu Glu Met Ala Ala Phe 
    370                 375                 380                 


Cys Arg Ser Ile Thr Lys Leu Lys Thr Lys Phe Pro Tyr Thr Asn His 
385                 390                 395                 400 


Arg Thr Asn Pro Gly Tyr Leu Leu Ser Pro Val Thr Ala Gln Arg Asn 
                405                 410                 415     


Ile Cys Gly Glu Asn Ala Ser Val Lys Val Ser Ile Asp Ile Glu Gly 
            420                 425                 430         


Phe Gln Leu Pro Val Thr Phe Thr Cys Asp Val Ser Ser Thr Val Glu 
        435                 440                 445             


Ile Ile Ile Met Gln Ala Leu Cys Trp Val His Asp Asp Leu Asn Gln 
    450                 455                 460                 


Val Asp Val Gly Ser Tyr Val Leu Lys Val Cys Gly Gln Glu Glu Val 
465                 470                 475                 480 


Leu Gln Asn Asn His Cys Leu Gly Ser His Glu His Ile Gln Asn Cys 
                485                 490                 495     


Arg Lys Trp Asp Thr Glu Ile Arg Leu Gln Leu Leu Thr Phe Ser Ala 
            500                 505                 510         


Met Cys Gln Asn Leu Ala Arg Thr Ala Glu Asp Asp Glu Thr Pro Val 
        515                 520                 525             


Asp Leu Asn Lys His Leu Tyr Gln Ile Glu Lys Pro Cys Lys Glu Ala 
    530                 535                 540                 


Met Thr Arg His Pro Val Glu Glu Leu Leu Asp Ser Tyr His Asn Gln 
545                 550                 555                 560 


Val Glu Leu Ala Leu Gln Ile Glu Asn Gln His Arg Ala Val Asp Gln 
                565                 570                 575     


Val Ile Lys Ala Val Arg Lys Ile Cys Ser Ala Leu Asp Gly Val Glu 
            580                 585                 590         


Thr Leu Ala Ile Thr Glu Ser Val Lys Lys Leu Lys Arg Ala Val Asn 
        595                 600                 605             


Leu Pro Arg Ser Lys Thr Ala Asp Val Thr Ser Leu Phe Gly Gly Glu 
    610                 615                 620                 


Asp Thr Ser Arg Ser Ser Thr Arg Gly Ser Leu Asn Pro Glu Asn Pro 
625                 630                 635                 640 


Val Gln Val Ser Ile Asn Gln Leu Thr Ala Ala Ile Tyr Asp Leu Leu 
                645                 650                 655     


Arg Leu His Ala Asn Ser Gly Arg Ser Pro Thr Asp Cys Ala Gln Ser 
            660                 665                 670         


Ser Lys Ser Val Lys Glu Ala Trp Thr Thr Thr Glu Gln Leu Gln Phe 
        675                 680                 685             


Thr Ile Phe Ala Ala His Gly Ile Ser Ser Asn Trp Val Ser Asn Tyr 
    690                 695                 700                 


Glu Lys Tyr Tyr Leu Ile Cys Ser Leu Ser His Asn Gly Lys Asp Leu 
705                 710                 715                 720 


Phe Lys Pro Ile Gln Ser Lys Lys Val Gly Thr Tyr Lys Asn Phe Phe 
                725                 730                 735     


Tyr Leu Ile Lys Trp Asp Glu Leu Ile Ile Phe Pro Ile Gln Ile Ser 
            740                 745                 750         


Gln Leu Pro Leu Glu Ser Val Leu His Leu Thr Leu Phe Gly Ile Leu 
        755                 760                 765             


Asn Gln Ser Ser Gly Ser Ser Pro Asp Ser Asn Lys Gln Arg Lys Gly 
    770                 775                 780                 


Pro Glu Ala Leu Gly Lys Val Ser Leu Pro Leu Phe Asp Phe Lys Arg 
785                 790                 795                 800 


Phe Leu Thr Cys Gly Thr Lys Leu Leu Tyr Leu Trp Thr Ser Ser His 
                805                 810                 815     


Thr Asn Ser Val Pro Gly Thr Val Thr Lys Lys Gly Tyr Val Met Glu 
            820                 825                 830         


Arg Ile Val Leu Gln Val Asp Phe Pro Ser Pro Ala Phe Asp Ile Ile 
        835                 840                 845             


Tyr Thr Thr Pro Gln Val Asp Arg Ser Ile Ile Gln Gln His Asn Leu 
    850                 855                 860                 


Glu Thr Leu Glu Asn Asp Ile Lys Gly Lys Leu Leu Asp Ile Leu His 
865                 870                 875                 880 


Lys Asp Ser Ser Leu Gly Leu Ser Lys Glu Asp Lys Ala Phe Leu Trp 
                885                 890                 895     


Glu Lys Arg Tyr Tyr Cys Phe Lys His Pro Asn Cys Leu Pro Lys Ile 
            900                 905                 910         


Leu Ala Ser Ala Pro Asn Trp Lys Trp Val Asn Leu Ala Lys Thr Tyr 
        915                 920                 925             


Ser Leu Leu His Gln Trp Pro Ala Leu Tyr Pro Leu Ile Ala Leu Glu 
    930                 935                 940                 


Leu Leu Asp Ser Lys Phe Ala Asp Gln Glu Val Arg Ser Leu Ala Val 
945                 950                 955                 960 


Thr Trp Ile Glu Ala Ile Ser Asp Asp Glu Leu Thr Asp Leu Leu Pro 
                965                 970                 975     


Gln Phe Val Gln Ala Leu Lys Tyr Glu Ile Tyr Leu Asn Ser Ser Leu 
            980                 985                 990         


Val Gln Phe Leu Leu Ser Arg Ala  Leu Gly Asn Ile Gln  Ile Ala His 
        995                 1000                 1005             


Asn Leu  Tyr Trp Leu Leu Lys  Asp Ala Leu His Asp  Val Gln Phe 
    1010                 1015                 1020             


Ser Thr  Arg Tyr Glu His Val  Leu Gly Ala Leu Leu  Ser Val Gly 
    1025                 1030                 1035             


Gly Lys  Arg Leu Arg Glu Glu  Leu Leu Lys Gln Thr  Lys Leu Val 
    1040                 1045                 1050             


Gln Leu  Leu Gly Gly Val Ala  Glu Lys Val Arg Gln  Ala Ser Gly 
    1055                 1060                 1065             


Ser Ala  Arg Gln Val Val Leu  Gln Arg Ser Met Glu  Arg Val Gln 
    1070                 1075                 1080             


Ser Phe  Phe Gln Lys Asn Lys  Cys Arg Leu Pro Leu  Lys Pro Ser 
    1085                 1090                 1095             


Leu Val  Ala Lys Glu Leu Asn  Ile Lys Ser Cys Ser  Phe Phe Ser 
    1100                 1105                 1110             


Ser Asn  Ala Val Pro Leu Lys  Val Thr Met Val Asn  Ala Asp Pro 
    1115                 1120                 1125             


Met Gly  Glu Glu Ile Asn Val  Met Phe Lys Val Gly  Glu Asp Leu 
    1130                 1135                 1140             


Arg Gln  Asp Met Leu Ala Leu  Gln Met Ile Lys Ile  Met Asp Lys 
    1145                 1150                 1155             


Ile Trp  Leu Lys Glu Gly Leu  Asp Leu Arg Met Val  Ile Phe Lys 
    1160                 1165                 1170             


Cys Leu  Ser Thr Gly Arg Asp  Arg Gly Met Val Glu  Leu Val Pro 
    1175                 1180                 1185             


Ala Ser  Asp Thr Leu Arg Lys  Ile Gln Val Glu Tyr  Gly Val Thr 
    1190                 1195                 1200             


Gly Ser  Phe Lys Asp Lys Pro  Leu Ala Glu Trp Leu  Arg Lys Tyr 
    1205                 1210                 1215             


Asn Pro  Ser Glu Glu Glu Tyr  Glu Lys Ala Ser Glu  Asn Phe Ile 
    1220                 1225                 1230             


Tyr Ser  Cys Ala Gly Cys Cys  Val Ala Thr Tyr Val  Leu Gly Ile 
    1235                 1240                 1245             


Cys Asp  Arg His Asn Asp Asn  Ile Met Leu Arg Ser  Thr Gly His 
    1250                 1255                 1260             


Met Phe  His Ile Asp Phe Gly  Lys Phe Leu Gly His  Ala Gln Met 
    1265                 1270                 1275             


Phe Gly  Ser Phe Lys Arg Asp  Arg Ala Pro Phe Val  Leu Thr Ser 
    1280                 1285                 1290             


Asp Met  Ala Tyr Val Ile Asn  Gly Gly Glu Lys Pro  Thr Ile Arg 
    1295                 1300                 1305             


Phe Gln  Leu Phe Val Asp Leu  Cys Cys Gln Ala Tyr  Asn Leu Ile 
    1310                 1315                 1320             


Arg Lys  Gln Thr Asn Leu Phe  Leu Asn Leu Leu Ser  Leu Met Ile 
    1325                 1330                 1335             


Pro Ser  Gly Leu Pro Glu Leu  Thr Ser Ile Gln Asp  Leu Lys Tyr 
    1340                 1345                 1350             


Val Arg  Asp Ala Leu Gln Pro  Gln Thr Thr Asp Ala  Glu Ala Thr 
    1355                 1360                 1365             


Ile Phe  Phe Thr Arg Leu Ile  Glu Ser Ser Leu Gly  Ser Ile Ala 
    1370                 1375                 1380             


Thr Lys  Phe Asn Phe Phe Ile  His Asn Leu Ala Gln  Leu Arg Phe 
    1385                 1390                 1395             


Ser Gly  Leu Pro Ser Asn Asp  Glu Pro Ile Leu Ser  Phe Ser Pro 
    1400                 1405                 1410             


Lys Thr  Tyr Ser Phe Arg Gln  Asp Gly Arg Ile Lys  Glu Val Ser 
    1415                 1420                 1425             


Val Phe  Thr Tyr His Lys Lys  Tyr Asn Pro Asp Lys  His Tyr Ile 
    1430                 1435                 1440             


Tyr Val  Val Arg Ile Leu Arg  Glu Gly Gln Ile Glu  Pro Ser Phe 
    1445                 1450                 1455             


Val Phe  Arg Thr Phe Asp Glu  Phe Gln Glu Leu His  Asn Lys Leu 
    1460                 1465                 1470             


Ser Ile  Ile Phe Pro Leu Trp  Lys Leu Pro Gly Phe  Pro Asn Arg 
    1475                 1480                 1485             


Met Val  Leu Gly Arg Thr His  Ile Lys Asp Val Ala  Ala Lys Arg 
    1490                 1495                 1500             


Lys Ile  Glu Leu Asn Ser Tyr  Leu Gln Ser Leu Met  Asn Ala Ser 
    1505                 1510                 1515             


Thr Asp  Val Ala Glu Cys Asp  Leu Val Cys Thr Phe  Phe His Pro 
    1520                 1525                 1530             


Leu Leu  Arg Asp Glu Lys Ala  Glu Gly Ile Ala Arg  Ser Ala Asp 
    1535                 1540                 1545             


Ala Gly  Ser Phe Ser Pro Thr  Pro Gly Gln Ile Gly  Gly Ala Val 
    1550                 1555                 1560             


Lys Leu  Ser Ile Ser Tyr Arg  Asn Gly Thr Leu Phe  Ile Met Val 
    1565                 1570                 1575             


Met His  Ile Lys Asp Leu Val  Thr Glu Asp Gly Ala  Asp Pro Asn 
    1580                 1585                 1590             


Pro Tyr  Val Lys Thr Tyr Leu  Leu Pro Asp Asn His  Lys Thr Ser 
    1595                 1600                 1605             


Lys Arg  Lys Thr Lys Ile Ser  Arg Lys Thr Arg Asn  Pro Thr Phe 
    1610                 1615                 1620             


Asn Glu  Met Leu Val Tyr Ser  Gly Tyr Ser Lys Glu  Thr Leu Arg 
    1625                 1630                 1635             


Gln Arg  Glu Leu Gln Leu Ser  Val Leu Ser Ala Glu  Ser Leu Arg 
    1640                 1645                 1650             


Glu Asn  Phe Phe Leu Gly Gly  Val Thr Leu Pro Leu  Lys Asp Phe 
    1655                 1660                 1665             


Asn Leu  Ser Lys Glu Thr Val  Lys Trp Tyr Gln Leu  Thr Ala Ala 
    1670                 1675                 1680             


Thr Tyr  Leu 
    1685     


<210>  3805
<211>  303
<212>  PRT
<213>  homo sapiens

<400>  3805

Met Ala Pro Ala Ala Asp Met Thr Ser Leu Pro Leu Gly Val Lys Val 
1               5                   10                  15      


Glu Asp Ser Ala Phe Gly Lys Pro Ala Gly Gly Gly Ala Gly Gln Ala 
            20                  25                  30          


Pro Ser Ala Ala Ala Ala Thr Ala Ala Ala Met Gly Ala Asp Glu Glu 
        35                  40                  45              


Gly Ala Lys Pro Lys Val Ser Pro Ser Leu Leu Pro Phe Ser Val Glu 
    50                  55                  60                  


Ala Leu Met Ala Asp His Arg Lys Pro Gly Ala Lys Glu Ser Ala Leu 
65                  70                  75                  80  


Ala Pro Ser Glu Gly Val Gln Ala Ala Gly Gly Ser Ala Gln Pro Leu 
                85                  90                  95      


Gly Val Pro Pro Gly Ser Leu Gly Ala Pro Asp Ala Pro Ser Ser Pro 
            100                 105                 110         


Arg Pro Leu Gly His Phe Ser Val Gly Gly Leu Leu Lys Leu Pro Glu 
        115                 120                 125             


Asp Ala Leu Val Lys Ala Glu Ser Pro Glu Lys Pro Glu Arg Thr Pro 
    130                 135                 140                 


Trp Met Gln Ser Pro Arg Phe Ser Pro Pro Pro Ala Arg Arg Leu Ser 
145                 150                 155                 160 


Pro Pro Ala Cys Thr Leu Arg Lys His Lys Thr Asn Arg Lys Pro Arg 
                165                 170                 175     


Thr Pro Phe Thr Thr Ala Gln Leu Leu Ala Leu Glu Arg Lys Phe Arg 
            180                 185                 190         


Gln Lys Gln Tyr Leu Ser Ile Ala Glu Arg Ala Glu Phe Ser Ser Ser 
        195                 200                 205             


Leu Ser Leu Thr Glu Thr Gln Val Lys Ile Trp Phe Gln Asn Arg Arg 
    210                 215                 220                 


Ala Lys Ala Lys Arg Leu Gln Glu Ala Glu Leu Glu Lys Leu Lys Met 
225                 230                 235                 240 


Ala Ala Lys Pro Met Leu Pro Pro Ala Ala Phe Gly Leu Ser Phe Pro 
                245                 250                 255     


Leu Gly Gly Pro Ala Ala Val Ala Ala Ala Ala Gly Ala Ser Leu Tyr 
            260                 265                 270         


Gly Ala Ser Gly Pro Phe Gln Arg Ala Ala Leu Pro Val Ala Pro Val 
        275                 280                 285             


Gly Leu Tyr Thr Ala His Val Gly Tyr Ser Met Tyr His Leu Thr 
    290                 295                 300             


<210>  3806
<211>  560
<212>  PRT
<213>  homo sapiens

<400>  3806

Met Pro Gln Thr Arg Ser Gln Ala Gln Ala Thr Ile Ser Phe Pro Lys 
1               5                   10                  15      


Arg Lys Leu Ser Arg Ala Leu Asn Lys Ala Lys Asn Ser Ser Asp Ala 
            20                  25                  30          


Lys Leu Glu Pro Thr Asn Val Gln Thr Val Thr Cys Ser Pro Arg Val 
        35                  40                  45              


Lys Ala Leu Pro Leu Ser Pro Arg Lys Arg Leu Gly Asp Asp Asn Leu 
    50                  55                  60                  


Cys Asn Thr Pro His Leu Pro Pro Cys Ser Pro Pro Lys Gln Gly Lys 
65                  70                  75                  80  


Lys Glu Asn Gly Pro Pro His Ser His Thr Leu Lys Gly Arg Arg Leu 
                85                  90                  95      


Val Phe Asp Asn Gln Leu Thr Ile Lys Ser Pro Ser Lys Arg Glu Leu 
            100                 105                 110         


Ala Lys Val His Gln Asn Lys Ile Leu Ser Ser Val Arg Lys Ser Gln 
        115                 120                 125             


Glu Ile Thr Thr Asn Ser Glu Gln Arg Cys Pro Leu Lys Lys Glu Ser 
    130                 135                 140                 


Ala Cys Val Arg Leu Phe Lys Gln Glu Gly Thr Cys Tyr Gln Gln Ala 
145                 150                 155                 160 


Lys Leu Val Leu Asn Thr Ala Val Pro Asp Arg Leu Pro Ala Arg Glu 
                165                 170                 175     


Arg Glu Met Asp Val Ile Arg Asn Phe Leu Arg Glu His Ile Cys Gly 
            180                 185                 190         


Lys Lys Ala Gly Ser Leu Tyr Leu Ser Gly Ala Pro Gly Thr Gly Lys 
        195                 200                 205             


Thr Ala Cys Leu Ser Arg Ile Leu Gln Asp Leu Lys Lys Glu Leu Lys 
    210                 215                 220                 


Gly Phe Lys Thr Ile Met Leu Asn Cys Met Ser Leu Arg Thr Ala Gln 
225                 230                 235                 240 


Ala Val Phe Pro Ala Ile Ala Gln Glu Ile Cys Gln Glu Glu Val Ser 
                245                 250                 255     


Arg Pro Ala Gly Lys Asp Met Met Arg Lys Leu Glu Lys His Met Thr 
            260                 265                 270         


Ala Glu Lys Gly Pro Met Ile Val Leu Val Leu Asp Glu Met Asp Gln 
        275                 280                 285             


Leu Asp Ser Lys Gly Gln Asp Val Leu Tyr Thr Leu Phe Glu Trp Pro 
    290                 295                 300                 


Trp Leu Ser Asn Ser His Leu Val Leu Ile Gly Ile Ala Asn Thr Leu 
305                 310                 315                 320 


Asp Leu Thr Asp Arg Ile Leu Pro Arg Leu Gln Ala Arg Glu Lys Cys 
                325                 330                 335     


Lys Pro Gln Leu Leu Asn Phe Pro Pro Tyr Thr Arg Asn Gln Ile Val 
            340                 345                 350         


Thr Ile Leu Gln Asp Arg Leu Asn Gln Val Ser Arg Asp Gln Val Leu 
        355                 360                 365             


Asp Asn Ala Ala Val Gln Phe Cys Ala Arg Lys Val Ser Ala Val Ser 
    370                 375                 380                 


Gly Asp Val Arg Lys Ala Leu Asp Val Cys Arg Arg Ala Ile Glu Ile 
385                 390                 395                 400 


Val Glu Ser Asp Val Lys Ser Gln Thr Ile Leu Lys Pro Leu Ser Glu 
                405                 410                 415     


Cys Lys Ser Pro Ser Glu Pro Leu Ile Pro Lys Arg Val Gly Leu Ile 
            420                 425                 430         


His Ile Ser Gln Val Ile Ser Glu Val Asp Gly Asn Arg Met Thr Leu 
        435                 440                 445             


Ser Gln Glu Gly Ala Gln Asp Ser Phe Pro Leu Gln Gln Lys Ile Leu 
    450                 455                 460                 


Val Cys Ser Leu Met Leu Leu Ile Arg Gln Leu Lys Ile Lys Glu Val 
465                 470                 475                 480 


Thr Leu Gly Lys Leu Tyr Glu Ala Tyr Ser Lys Val Cys Arg Lys Gln 
                485                 490                 495     


Gln Val Ala Ala Val Asp Gln Ser Glu Cys Leu Ser Leu Ser Gly Leu 
            500                 505                 510         


Leu Glu Ala Arg Gly Ile Leu Gly Leu Lys Arg Asn Lys Glu Thr Arg 
        515                 520                 525             


Leu Thr Lys Val Phe Phe Lys Ile Glu Glu Lys Glu Ile Glu His Ala 
    530                 535                 540                 


Leu Lys Asp Lys Ala Leu Ile Gly Asn Ile Leu Ala Thr Gly Leu Pro 
545                 550                 555                 560 


<210>  3807
<211>  470
<212>  PRT
<213>  homo sapiens

<400>  3807

Met Ala Ala Thr Leu Leu Met Ala Gly Ser Gln Ala Pro Val Thr Phe 
1               5                   10                  15      


Glu Asp Met Ala Met Tyr Leu Thr Arg Glu Glu Trp Arg Pro Leu Asp 
            20                  25                  30          


Ala Ala Gln Arg Asp Leu Tyr Arg Asp Val Met Gln Glu Asn Tyr Gly 
        35                  40                  45              


Asn Val Val Ser Leu Asp Phe Glu Ile Arg Ser Glu Asn Glu Val Asn 
    50                  55                  60                  


Pro Lys Gln Glu Ile Ser Glu Asp Val Gln Phe Gly Thr Thr Ser Glu 
65                  70                  75                  80  


Arg Pro Ala Glu Asn Ala Glu Glu Asn Pro Glu Ser Glu Glu Gly Phe 
                85                  90                  95      


Glu Ser Gly Asp Arg Ser Glu Arg Gln Trp Gly Asp Leu Thr Ala Glu 
            100                 105                 110         


Glu Trp Val Ser Tyr Pro Leu Gln Pro Val Thr Asp Leu Leu Val His 
        115                 120                 125             


Lys Glu Val His Thr Gly Ile Arg Tyr His Ile Cys Ser His Cys Gly 
    130                 135                 140                 


Lys Ala Phe Ser Gln Ile Ser Asp Leu Asn Arg His Gln Lys Thr His 
145                 150                 155                 160 


Thr Gly Asp Arg Pro Tyr Lys Cys Tyr Glu Cys Gly Lys Gly Phe Ser 
                165                 170                 175     


Arg Ser Ser His Leu Ile Gln His Gln Arg Thr His Thr Gly Glu Arg 
            180                 185                 190         


Pro Tyr Asp Cys Asn Glu Cys Gly Lys Ser Phe Gly Arg Ser Ser His 
        195                 200                 205             


Leu Ile Gln His Gln Thr Ile His Thr Gly Glu Lys Pro His Lys Cys 
    210                 215                 220                 


Asn Glu Cys Gly Lys Ser Phe Cys Arg Leu Ser His Leu Ile Gln His 
225                 230                 235                 240 


Gln Arg Thr His Ser Gly Glu Lys Pro Tyr Glu Cys Glu Glu Cys Gly 
                245                 250                 255     


Lys Ser Phe Ser Arg Ser Ser His Leu Ala Gln His Gln Arg Thr His 
            260                 265                 270         


Thr Gly Glu Lys Pro Tyr Glu Cys Asn Glu Cys Gly Arg Gly Phe Ser 
        275                 280                 285             


Glu Arg Ser Asp Leu Ile Lys His Tyr Arg Val His Thr Gly Glu Arg 
    290                 295                 300                 


Pro Tyr Lys Cys Asp Glu Cys Gly Lys Asn Phe Ser Gln Asn Ser Asp 
305                 310                 315                 320 


Leu Val Arg His Arg Arg Ala His Thr Gly Glu Lys Pro Tyr His Cys 
                325                 330                 335     


Asn Glu Cys Gly Glu Asn Phe Ser Arg Ile Ser His Leu Val Gln His 
            340                 345                 350         


Gln Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Ala Cys Gly 
        355                 360                 365             


Lys Ser Phe Ser Arg Ser Ser His Leu Ile Thr His Gln Lys Ile His 
    370                 375                 380                 


Thr Gly Glu Lys Pro Tyr Glu Cys Asn Glu Cys Trp Arg Ser Phe Gly 
385                 390                 395                 400 


Glu Arg Ser Asp Leu Ile Lys His Gln Arg Thr His Thr Gly Glu Lys 
                405                 410                 415     


Pro Tyr Glu Cys Val Gln Cys Gly Lys Gly Phe Thr Gln Ser Ser Asn 
            420                 425                 430         


Leu Ile Thr His Gln Arg Val His Thr Gly Glu Lys Pro Tyr Glu Cys 
        435                 440                 445             


Thr Glu Cys Glu Lys Ser Phe Ser Arg Ser Ser Ala Leu Ile Lys His 
    450                 455                 460                 


Lys Arg Val His Thr Asp 
465                 470 


<210>  3808
<211>  374
<212>  PRT
<213>  homo sapiens

<400>  3808

Met Val Leu Trp Glu Ser Pro Arg Gln Cys Ser Ser Trp Thr Leu Cys 
1               5                   10                  15      


Glu Gly Phe Cys Trp Leu Leu Leu Leu Pro Val Met Leu Leu Ile Val 
            20                  25                  30          


Ala Arg Pro Val Lys Leu Ala Ala Phe Pro Thr Ser Leu Ser Asp Cys 
        35                  40                  45              


Gln Thr Pro Thr Gly Trp Asn Cys Ser Gly Tyr Asp Asp Arg Glu Asn 
    50                  55                  60                  


Asp Leu Phe Leu Cys Asp Thr Asn Thr Cys Lys Phe Asp Gly Glu Cys 
65                  70                  75                  80  


Leu Arg Ile Gly Asp Thr Val Thr Cys Val Cys Gln Phe Lys Cys Asn 
                85                  90                  95      


Asn Asp Tyr Val Pro Val Cys Gly Ser Asn Gly Glu Ser Tyr Gln Asn 
            100                 105                 110         


Glu Cys Tyr Leu Arg Gln Ala Ala Cys Lys Gln Gln Ser Glu Ile Leu 
        115                 120                 125             


Val Val Ser Glu Gly Ser Cys Ala Thr Asp Ala Gly Ser Gly Ser Gly 
    130                 135                 140                 


Asp Gly Val His Glu Gly Ser Gly Glu Thr Ser Gln Lys Glu Thr Ser 
145                 150                 155                 160 


Thr Cys Asp Ile Cys Gln Phe Gly Ala Glu Cys Asp Glu Asp Ala Glu 
                165                 170                 175     


Asp Val Trp Cys Val Cys Asn Ile Asp Cys Ser Gln Thr Asn Phe Asn 
            180                 185                 190         


Pro Leu Cys Ala Ser Asp Gly Lys Ser Tyr Asp Asn Ala Cys Gln Ile 
        195                 200                 205             


Lys Glu Ala Ser Cys Gln Lys Gln Glu Lys Ile Glu Val Met Ser Leu 
    210                 215                 220                 


Gly Arg Cys Gln Asp Asn Thr Thr Thr Thr Thr Lys Ser Glu Asp Gly 
225                 230                 235                 240 


His Tyr Ala Arg Thr Asp Tyr Ala Glu Asn Ala Asn Lys Leu Glu Glu 
                245                 250                 255     


Ser Ala Arg Glu His His Ile Pro Cys Pro Glu His Tyr Asn Gly Phe 
            260                 265                 270         


Cys Met His Gly Lys Cys Glu His Ser Ile Asn Met Gln Glu Pro Ser 
        275                 280                 285             


Cys Arg Cys Asp Ala Gly Tyr Thr Gly Gln His Cys Glu Lys Lys Asp 
    290                 295                 300                 


Tyr Ser Val Leu Tyr Val Val Pro Gly Pro Val Arg Phe Gln Tyr Val 
305                 310                 315                 320 


Leu Ile Ala Ala Val Ile Gly Thr Ile Gln Ile Ala Val Ile Cys Val 
                325                 330                 335     


Val Val Leu Cys Ile Thr Arg Lys Cys Pro Arg Ser Asn Arg Ile His 
            340                 345                 350         


Arg Gln Lys Gln Asn Thr Gly His Tyr Ser Ser Asp Asn Thr Thr Arg 
        355                 360                 365             


Ala Ser Thr Arg Leu Ile 
    370                 


<210>  3809
<211>  392
<212>  PRT
<213>  homo sapiens

<400>  3809

Met Glu Asp Leu Asp Gln Ser Pro Leu Val Ser Ser Ser Asp Ser Pro 
1               5                   10                  15      


Pro Arg Pro Gln Pro Ala Phe Lys Tyr Gln Phe Val Arg Glu Pro Glu 
            20                  25                  30          


Asp Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp Glu Asp Glu Asp 
        35                  40                  45              


Leu Glu Glu Leu Glu Val Leu Glu Arg Lys Pro Ala Ala Gly Leu Ser 
    50                  55                  60                  


Ala Ala Pro Val Pro Thr Ala Pro Ala Ala Gly Ala Pro Leu Met Asp 
65                  70                  75                  80  


Phe Gly Asn Asp Phe Val Pro Pro Ala Pro Arg Gly Pro Leu Pro Ala 
                85                  90                  95      


Ala Pro Pro Val Ala Pro Glu Arg Gln Pro Ser Trp Asp Pro Ser Pro 
            100                 105                 110         


Val Ser Ser Thr Val Pro Ala Pro Ser Pro Leu Ser Ala Ala Ala Val 
        115                 120                 125             


Ser Pro Ser Lys Leu Pro Glu Asp Asp Glu Pro Pro Ala Arg Pro Pro 
    130                 135                 140                 


Pro Pro Pro Pro Ala Ser Val Ser Pro Gln Ala Glu Pro Val Trp Thr 
145                 150                 155                 160 


Pro Pro Ala Pro Ala Pro Ala Ala Pro Pro Ser Thr Pro Ala Ala Pro 
                165                 170                 175     


Lys Arg Arg Gly Ser Ser Gly Ser Val Asp Glu Thr Leu Phe Ala Leu 
            180                 185                 190         


Pro Ala Ala Ser Glu Pro Val Ile Arg Ser Ser Ala Val Val Asp Leu 
        195                 200                 205             


Leu Tyr Trp Arg Asp Ile Lys Lys Thr Gly Val Val Phe Gly Ala Ser 
    210                 215                 220                 


Leu Phe Leu Leu Leu Ser Leu Thr Val Phe Ser Ile Val Ser Val Thr 
225                 230                 235                 240 


Ala Tyr Ile Ala Leu Ala Leu Leu Ser Val Thr Ile Ser Phe Arg Ile 
                245                 250                 255     


Tyr Lys Gly Val Ile Gln Ala Ile Gln Lys Ser Asp Glu Gly His Pro 
            260                 265                 270         


Phe Arg Ala Tyr Leu Glu Ser Glu Val Ala Ile Ser Glu Glu Leu Val 
        275                 280                 285             


Gln Lys Tyr Ser Asn Ser Ala Leu Gly His Val Asn Cys Thr Ile Lys 
    290                 295                 300                 


Glu Leu Arg Arg Leu Phe Leu Val Asp Asp Leu Val Asp Ser Leu Lys 
305                 310                 315                 320 


Phe Ala Val Leu Met Trp Val Phe Thr Tyr Val Gly Ala Leu Phe Asn 
                325                 330                 335     


Gly Leu Thr Leu Leu Ile Leu Ala Leu Ile Ser Leu Phe Ser Val Pro 
            340                 345                 350         


Val Ile Tyr Glu Arg His Gln Ala Gln Ile Asp His Tyr Leu Gly Leu 
        355                 360                 365             


Ala Asn Lys Asn Val Lys Asp Ala Met Ala Lys Ile Gln Ala Lys Ile 
    370                 375                 380                 


Pro Gly Leu Lys Arg Lys Ala Glu 
385                 390         


<210>  3810
<211>  253
<212>  PRT
<213>  homo sapiens

<400>  3810

Met Ala Ala Ala Phe Arg Lys Ala Ala Lys Ser Arg Gln Arg Glu His 
1               5                   10                  15      


Arg Glu Arg Ser Gln Pro Gly Phe Arg Lys His Leu Gly Leu Leu Glu 
            20                  25                  30          


Lys Lys Lys Asp Tyr Lys Leu Arg Ala Asp Asp Tyr Arg Lys Lys Gln 
        35                  40                  45              


Glu Tyr Leu Lys Ala Leu Arg Lys Lys Ala Leu Glu Lys Asn Pro Asp 
    50                  55                  60                  


Glu Phe Tyr Tyr Lys Met Thr Arg Val Lys Leu Gln Asp Gly Val His 
65                  70                  75                  80  


Ile Ile Lys Glu Thr Lys Glu Glu Val Thr Pro Glu Gln Leu Lys Leu 
                85                  90                  95      


Met Arg Thr Gln Asp Val Lys Tyr Ile Glu Met Lys Arg Val Ala Glu 
            100                 105                 110         


Ala Lys Lys Ile Glu Arg Leu Lys Ser Glu Leu His Leu Leu Asp Phe 
        115                 120                 125             


Gln Gly Lys Gln Gln Asn Lys His Val Phe Phe Phe Asp Thr Lys Lys 
    130                 135                 140                 


Glu Val Glu Gln Phe Asp Val Ala Thr His Leu Gln Thr Ala Pro Glu 
145                 150                 155                 160 


Leu Val Asp Arg Val Phe Asn Arg Pro Arg Ile Glu Thr Leu Gln Lys 
                165                 170                 175     


Glu Lys Val Lys Gly Val Thr Asn Gln Thr Gly Leu Lys Arg Ile Ala 
            180                 185                 190         


Lys Glu Arg Gln Lys Gln Tyr Asn Cys Leu Thr Gln Arg Ile Glu Arg 
        195                 200                 205             


Glu Lys Lys Leu Phe Val Ile Ala Gln Lys Ile Gln Thr Arg Lys Asp 
    210                 215                 220                 


Leu Met Asp Lys Thr Gln Lys Val Lys Val Lys Lys Glu Thr Val Asn 
225                 230                 235                 240 


Ser Pro Ala Ile Tyr Lys Phe Gln Ser Arg Arg Lys Arg 
                245                 250             


<210>  3811
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  3811

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  3812
<211>  432
<212>  PRT
<213>  homo sapiens

<400>  3812

Met His Leu Arg Ile His Ala Arg Arg Ser Pro Pro Arg Arg Pro Ala 
1               5                   10                  15      


Trp Thr Leu Gly Ile Trp Phe Leu Phe Trp Gly Cys Ile Val Ser Ser 
            20                  25                  30          


Val Trp Ser Ser Ser Asn Val Ala Ser Ser Ser Ser Thr Ser Ser Ser 
        35                  40                  45              


Pro Gly Ser His Ser Gln His Glu His His Phe His Gly Ser Lys His 
    50                  55                  60                  


His Ser Val Pro Ile Ser Ile Tyr Arg Ser Pro Val Ser Leu Arg Gly 
65                  70                  75                  80  


Gly His Ala Gly Ala Thr Tyr Ile Phe Gly Lys Ser Gly Gly Leu Ile 
                85                  90                  95      


Leu Tyr Thr Trp Pro Ala Asn Asp Arg Pro Ser Thr Arg Ser Asp Arg 
            100                 105                 110         


Leu Ala Val Gly Phe Ser Thr Thr Val Lys Asp Gly Ile Leu Val Arg 
        115                 120                 125             


Ile Asp Ser Ala Pro Gly Leu Gly Asp Phe Leu Gln Leu His Ile Glu 
    130                 135                 140                 


Gln Gly Lys Ile Gly Val Val Phe Asn Ile Gly Thr Val Asp Ile Ser 
145                 150                 155                 160 


Ile Lys Glu Glu Arg Thr Pro Val Asn Asp Gly Lys Tyr His Val Val 
                165                 170                 175     


Arg Phe Thr Arg Asn Gly Gly Asn Ala Thr Leu Gln Val Asp Asn Trp 
            180                 185                 190         


Pro Val Asn Glu His Tyr Pro Thr Gly Arg Gln Leu Thr Ile Phe Asn 
        195                 200                 205             


Thr Gln Ala Gln Ile Ala Ile Gly Gly Lys Asp Lys Gly Arg Leu Phe 
    210                 215                 220                 


Gln Gly Gln Leu Ser Gly Leu Tyr Tyr Asp Gly Leu Lys Val Leu Asn 
225                 230                 235                 240 


Met Ala Ala Glu Asn Asn Pro Asn Ile Lys Ile Asn Gly Ser Val Arg 
                245                 250                 255     


Leu Val Gly Glu Val Pro Ser Ile Leu Gly Thr Thr Gln Thr Thr Ser 
            260                 265                 270         


Met Pro Pro Glu Met Ser Thr Thr Val Met Glu Thr Thr Thr Thr Met 
        275                 280                 285             


Ala Thr Thr Thr Thr Arg Lys Asn Arg Ser Thr Ala Ser Ile Gln Pro 
    290                 295                 300                 


Thr Ser Asp Asp Leu Val Ser Ser Ala Glu Cys Ser Ser Asp Asp Glu 
305                 310                 315                 320 


Asp Phe Val Glu Cys Glu Pro Ser Thr Gly Arg Ser Ala Asn Pro Thr 
                325                 330                 335     


Glu Pro Gly Ile Arg Arg Val Pro Gly Ala Ser Glu Val Ile Arg Glu 
            340                 345                 350         


Ser Ser Ser Thr Thr Gly Met Val Val Gly Ile Val Ala Ala Ala Ala 
        355                 360                 365             


Leu Cys Ile Leu Ile Leu Leu Tyr Ala Met Tyr Lys Tyr Arg Asn Arg 
    370                 375                 380                 


Asp Glu Gly Ser Tyr Gln Val Asp Glu Thr Arg Asn Tyr Ile Ser Asn 
385                 390                 395                 400 


Ser Ala Gln Ser Asn Gly Thr Leu Met Lys Glu Lys Gln Gln Ser Ser 
                405                 410                 415     


Lys Ser Gly His Lys Lys Gln Lys Asn Lys Asp Arg Glu Tyr Tyr Val 
            420                 425                 430         


<210>  3813
<211>  459
<212>  PRT
<213>  homo sapiens

<400>  3813

Met His Leu Arg Ile His Ala Arg Arg Ser Pro Pro Arg Arg Pro Ala 
1               5                   10                  15      


Trp Thr Leu Gly Ile Trp Phe Leu Phe Trp Gly Cys Ile Val Ser Ser 
            20                  25                  30          


Val Trp Ser Ser Ser Asn Val Ala Ser Ser Ser Ser Thr Ser Ser Ser 
        35                  40                  45              


Pro Gly Ser His Ser Gln His Glu His His Phe His Gly Ser Lys His 
    50                  55                  60                  


His Ser Val Pro Ile Ser Ile Tyr Arg Ser Pro Val Ser Leu Arg Gly 
65                  70                  75                  80  


Gly His Ala Gly Ala Thr Tyr Ile Phe Gly Lys Ser Gly Gly Leu Ile 
                85                  90                  95      


Leu Tyr Thr Trp Pro Ala Asn Asp Arg Pro Ser Thr Arg Ser Asp Arg 
            100                 105                 110         


Leu Ala Val Gly Phe Ser Thr Thr Val Lys Asp Gly Ile Leu Val Arg 
        115                 120                 125             


Ile Asp Ser Ala Pro Gly Leu Gly Asp Phe Leu Gln Leu His Ile Glu 
    130                 135                 140                 


Gln Gly Lys Ile Gly Val Val Phe Asn Ile Gly Thr Val Asp Ile Ser 
145                 150                 155                 160 


Ile Lys Glu Glu Arg Thr Pro Val Asn Asp Gly Lys Tyr His Val Val 
                165                 170                 175     


Arg Phe Thr Arg Asn Gly Gly Asn Ala Thr Leu Gln Val Asp Asn Trp 
            180                 185                 190         


Pro Val Asn Glu His Tyr Pro Thr Gly Asn Thr Asp Asn Glu Arg Phe 
        195                 200                 205             


Gln Met Val Lys Gln Lys Ile Pro Phe Lys Tyr Asn Arg Pro Val Glu 
    210                 215                 220                 


Glu Trp Leu Gln Glu Lys Gly Arg Gln Leu Thr Ile Phe Asn Thr Gln 
225                 230                 235                 240 


Ala Gln Ile Ala Ile Gly Gly Lys Asp Lys Gly Arg Leu Phe Gln Gly 
                245                 250                 255     


Gln Leu Ser Gly Leu Tyr Tyr Asp Gly Leu Lys Val Leu Asn Met Ala 
            260                 265                 270         


Ala Glu Asn Asn Pro Asn Ile Lys Ile Asn Gly Ser Val Arg Leu Val 
        275                 280                 285             


Gly Glu Val Pro Ser Ile Leu Gly Thr Thr Gln Thr Thr Ser Met Pro 
    290                 295                 300                 


Pro Glu Met Ser Thr Thr Val Met Glu Thr Thr Thr Thr Met Ala Thr 
305                 310                 315                 320 


Thr Thr Thr Arg Lys Asn Arg Ser Thr Ala Ser Ile Gln Pro Thr Ser 
                325                 330                 335     


Asp Asp Leu Val Ser Ser Ala Glu Cys Ser Ser Asp Asp Glu Asp Phe 
            340                 345                 350         


Val Glu Cys Glu Pro Ser Thr Ala Asn Pro Thr Glu Pro Gly Ile Arg 
        355                 360                 365             


Arg Val Pro Gly Ala Ser Glu Val Ile Arg Glu Ser Ser Ser Thr Thr 
    370                 375                 380                 


Gly Met Val Val Gly Ile Val Ala Ala Ala Ala Leu Cys Ile Leu Ile 
385                 390                 395                 400 


Leu Leu Tyr Ala Met Tyr Lys Tyr Arg Asn Arg Asp Glu Gly Ser Tyr 
                405                 410                 415     


Gln Val Asp Glu Thr Arg Asn Tyr Ile Ser Asn Ser Ala Gln Ser Asn 
            420                 425                 430         


Gly Thr Leu Met Lys Glu Lys Gln Gln Ser Ser Lys Ser Gly His Lys 
        435                 440                 445             


Lys Gln Lys Asn Lys Asp Arg Glu Tyr Tyr Val 
    450                 455                 


<210>  3814
<211>  520
<212>  PRT
<213>  homo sapiens

<400>  3814

Met Arg Val Glu Ser Gly Ser Ala Gln Glu Arg Gly Ile Leu Leu Glu 
1               5                   10                  15      


Ser Leu Ser Thr Leu Leu Glu Lys Thr Thr Ala Ser His Glu Gly Arg 
            20                  25                  30          


Ala Pro Gly Asn Arg Glu Leu Thr Asp Leu Leu Pro Pro Glu Val Cys 
        35                  40                  45              


Ser Leu Leu Asn Pro Ala Ala Ile Tyr Ala Asn Asn Glu Ile Ser Leu 
    50                  55                  60                  


Arg Asp Val Glu Val Tyr Gly Phe Asp Tyr Asp Tyr Thr Leu Ala Gln 
65                  70                  75                  80  


Tyr Ala Asp Ala Leu His Pro Glu Ile Phe Ser Thr Ala Arg Asp Ile 
                85                  90                  95      


Leu Ile Glu His Tyr Lys Tyr Pro Glu Gly Ile Arg Lys Tyr Asp Tyr 
            100                 105                 110         


Asn Pro Ser Phe Ala Ile Arg Gly Leu His Tyr Asp Ile Gln Lys Ser 
        115                 120                 125             


Leu Leu Met Lys Ile Asp Ala Phe His Tyr Val Gln Leu Gly Thr Ala 
    130                 135                 140                 


Tyr Arg Gly Leu Gln Pro Val Pro Asp Glu Glu Val Ile Glu Leu Tyr 
145                 150                 155                 160 


Gly Gly Thr Gln His Ile Pro Leu Tyr Gln Met Ser Gly Phe Tyr Gly 
                165                 170                 175     


Lys Gly Pro Ser Ile Lys Gln Phe Met Asp Ile Phe Ser Leu Pro Glu 
            180                 185                 190         


Met Ala Leu Leu Ser Cys Val Val Asp Tyr Phe Leu Gly His Ser Leu 
        195                 200                 205             


Glu Phe Asp Gln Ala His Leu Tyr Lys Asp Val Thr Asp Ala Ile Arg 
    210                 215                 220                 


Asp Val His Val Lys Gly Leu Met Tyr Gln Trp Ile Glu Gln Asp Met 
225                 230                 235                 240 


Glu Lys Tyr Ile Leu Arg Gly Asp Glu Thr Phe Ala Val Leu Ser Arg 
                245                 250                 255     


Leu Val Ala His Gly Lys Gln Leu Phe Leu Ile Thr Asn Ser Pro Phe 
            260                 265                 270         


Ser Phe Val Asp Lys Gly Met Arg His Met Val Gly Pro Asp Trp Arg 
        275                 280                 285             


Gln Leu Phe Asp Val Val Ile Val Gln Ala Asp Lys Pro Ser Phe Phe 
    290                 295                 300                 


Thr Asp Arg Arg Lys Pro Phe Arg Lys Leu Asp Glu Lys Gly Ser Leu 
305                 310                 315                 320 


Gln Trp Asp Arg Ile Thr Arg Leu Glu Lys Gly Lys Ile Tyr Arg Gln 
                325                 330                 335     


Gly Asn Leu Phe Asp Phe Leu Arg Leu Thr Glu Trp Arg Gly Pro Arg 
            340                 345                 350         


Val Leu Tyr Phe Gly Asp His Leu Tyr Ser Asp Leu Ala Asp Leu Met 
        355                 360                 365             


Leu Arg His Gly Trp Arg Thr Gly Ala Ile Ile Pro Glu Leu Glu Arg 
    370                 375                 380                 


Glu Ile Arg Ile Ile Asn Thr Glu Gln Tyr Met His Ser Leu Thr Trp 
385                 390                 395                 400 


Gln Gln Ala Leu Thr Gly Leu Leu Glu Arg Met Gln Thr Tyr Gln Asp 
                405                 410                 415     


Ala Glu Ser Arg Gln Val Leu Ala Ala Trp Met Lys Glu Arg Gln Glu 
            420                 425                 430         


Leu Arg Cys Ile Thr Lys Ala Leu Phe Asn Ala Gln Phe Gly Ser Ile 
        435                 440                 445             


Phe Arg Thr Phe His Asn Pro Thr Tyr Phe Ser Arg Arg Leu Val Arg 
    450                 455                 460                 


Phe Ser Asp Leu Tyr Met Ala Ser Leu Ser Cys Leu Leu Asn Tyr Arg 
465                 470                 475                 480 


Val Asp Phe Thr Phe Tyr Pro Arg Arg Thr Pro Leu Gln His Glu Ala 
                485                 490                 495     


Pro Leu Trp Met Asp Gln Leu Cys Thr Gly Cys Met Lys Thr Pro Phe 
            500                 505                 510         


Leu Gly Asp Met Ala His Ile Arg 
        515                 520 


<210>  3815
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  3815

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  3816
<211>  846
<212>  PRT
<213>  homo sapiens

<400>  3816

Met Glu Ala Pro Leu Arg Pro Ala Ala Asp Ile Leu Arg Arg Asn Pro 
1               5                   10                  15      


Gln Gln Asp Tyr Glu Leu Val Gln Arg Val Gly Ser Gly Thr Tyr Gly 
            20                  25                  30          


Asp Val Tyr Lys Ala Arg Asn Val His Thr Gly Glu Leu Ala Ala Val 
        35                  40                  45              


Lys Ile Ile Lys Leu Glu Pro Gly Asp Asp Phe Ser Leu Ile Gln Gln 
    50                  55                  60                  


Glu Ile Phe Met Val Lys Glu Cys Lys His Cys Asn Ile Val Ala Tyr 
65                  70                  75                  80  


Phe Gly Ser Tyr Leu Ser Arg Glu Lys Leu Trp Ile Cys Met Glu Tyr 
                85                  90                  95      


Cys Gly Gly Gly Ser Leu Gln Asp Ile Tyr His Val Thr Gly Pro Leu 
            100                 105                 110         


Ser Glu Leu Gln Ile Ala Tyr Val Cys Arg Glu Thr Leu Gln Gly Leu 
        115                 120                 125             


Ala Tyr Leu His Thr Lys Gly Lys Met His Arg Asp Ile Lys Gly Ala 
    130                 135                 140                 


Asn Ile Leu Leu Thr Asp His Gly Asp Val Lys Leu Ala Asp Phe Gly 
145                 150                 155                 160 


Val Ala Ala Lys Ile Thr Ala Thr Ile Ala Lys Arg Lys Ser Phe Ile 
                165                 170                 175     


Gly Thr Pro Tyr Trp Met Ala Pro Glu Val Ala Ala Val Glu Lys Asn 
            180                 185                 190         


Gly Gly Tyr Asn Gln Leu Cys Asp Ile Trp Ala Val Gly Ile Thr Ala 
        195                 200                 205             


Ile Glu Leu Gly Glu Leu Gln Pro Pro Met Phe Asp Leu His Pro Met 
    210                 215                 220                 


Arg Ala Leu Phe Leu Met Ser Lys Ser Asn Phe Gln Pro Pro Lys Leu 
225                 230                 235                 240 


Lys Asp Lys Thr Lys Trp Ser Ser Thr Phe His Asn Phe Val Lys Ile 
                245                 250                 255     


Ala Leu Thr Lys Asn Pro Lys Lys Arg Pro Thr Ala Glu Arg Leu Leu 
            260                 265                 270         


Thr His Thr Phe Val Ala Gln Pro Gly Leu Ser Arg Ala Leu Ala Val 
        275                 280                 285             


Glu Leu Leu Asp Lys Val Asn Asn Pro Asp Asn His Ala His Tyr Thr 
    290                 295                 300                 


Glu Ala Asp Asp Asp Asp Phe Glu Pro His Ala Ile Ile Arg His Thr 
305                 310                 315                 320 


Ile Arg Ser Thr Asn Arg Asn Ala Arg Ala Glu Arg Thr Ala Ser Glu 
                325                 330                 335     


Ile Asn Phe Asp Lys Leu Gln Phe Glu Pro Pro Leu Arg Lys Glu Thr 
            340                 345                 350         


Glu Ala Arg Asp Glu Met Gly Leu Ser Ser Asp Pro Asn Phe Met Leu 
        355                 360                 365             


Gln Trp Asn Pro Phe Val Asp Gly Ala Asn Thr Gly Lys Ser Thr Ser 
    370                 375                 380                 


Lys Arg Ala Ile Pro Pro Pro Leu Pro Pro Lys Pro Arg Ile Ser Ser 
385                 390                 395                 400 


Tyr Pro Glu Asp Asn Phe Pro Asp Glu Glu Lys Ala Ser Thr Ile Lys 
                405                 410                 415     


His Cys Pro Asp Ser Glu Ser Arg Ala Pro Gln Ile Leu Arg Arg Gln 
            420                 425                 430         


Ser Ser Pro Ser Cys Gly Pro Val Ala Glu Thr Ser Ser Ile Gly Asn 
        435                 440                 445             


Gly Asp Gly Ile Ser Lys Leu Met Ser Glu Asn Thr Glu Gly Ser Ala 
    450                 455                 460                 


Gln Ala Pro Gln Leu Pro Arg Lys Lys Asp Lys Arg Asp Phe Pro Lys 
465                 470                 475                 480 


Pro Ala Ile Asn Gly Leu Pro Pro Thr Pro Lys Val Leu Met Gly Ala 
                485                 490                 495     


Cys Phe Ser Lys Val Phe Asp Gly Cys Pro Leu Lys Ile Asn Cys Ala 
            500                 505                 510         


Thr Ser Trp Ile His Pro Asp Thr Lys Asp Gln Tyr Ile Ile Phe Gly 
        515                 520                 525             


Thr Glu Asp Gly Ile Tyr Thr Leu Asn Leu Asn Glu Leu His Glu Ala 
    530                 535                 540                 


Thr Met Glu Gln Leu Phe Pro Arg Lys Cys Thr Trp Leu Tyr Val Ile 
545                 550                 555                 560 


Asn Asn Thr Leu Met Ser Leu Ser Glu Gly Lys Thr Phe Gln Leu Tyr 
                565                 570                 575     


Ser His Asn Leu Ile Ala Leu Phe Glu His Ala Lys Lys Pro Gly Leu 
            580                 585                 590         


Ala Ala His Ile Gln Thr His Arg Phe Pro Asp Arg Ile Leu Pro Arg 
        595                 600                 605             


Lys Phe Ala Leu Thr Thr Lys Ile Pro Asp Thr Lys Gly Cys His Lys 
    610                 615                 620                 


Cys Cys Ile Val Arg Asn Pro Tyr Thr Gly His Lys Tyr Leu Cys Gly 
625                 630                 635                 640 


Ala Leu Gln Ser Gly Ile Val Leu Leu Gln Trp Tyr Glu Pro Met Gln 
                645                 650                 655     


Lys Phe Met Leu Ile Lys His Phe Asp Phe Pro Leu Pro Ser Pro Leu 
            660                 665                 670         


Asn Val Phe Glu Met Leu Val Ile Pro Glu Gln Glu Tyr Pro Met Val 
        675                 680                 685             


Cys Val Ala Ile Ser Lys Gly Thr Glu Ser Asn Gln Val Val Gln Phe 
    690                 695                 700                 


Glu Thr Ile Asn Leu Asn Ser Ala Ser Ser Trp Phe Thr Glu Ile Gly 
705                 710                 715                 720 


Ala Gly Ser Gln Gln Leu Asp Ser Ile His Val Thr Gln Leu Glu Arg 
                725                 730                 735     


Asp Thr Val Leu Val Cys Leu Asp Lys Phe Val Lys Ile Val Asn Leu 
            740                 745                 750         


Gln Gly Lys Leu Lys Ser Ser Lys Lys Leu Ala Ser Glu Leu Ser Phe 
        755                 760                 765             


Asp Phe Arg Ile Glu Ser Val Val Cys Leu Gln Asp Ser Val Leu Ala 
    770                 775                 780                 


Phe Trp Lys His Gly Met Gln Gly Lys Ser Phe Lys Ser Asp Glu Val 
785                 790                 795                 800 


Thr Gln Glu Ile Ser Asp Glu Thr Arg Val Phe Arg Leu Leu Gly Ser 
                805                 810                 815     


Asp Arg Val Val Val Leu Glu Ser Arg Pro Thr Glu Asn Pro Thr Ala 
            820                 825                 830         


His Ser Asn Leu Tyr Ile Leu Ala Gly His Glu Asn Ser Tyr 
        835                 840                 845     


<210>  3817
<211>  325
<212>  PRT
<213>  homo sapiens

<400>  3817

Met Pro Arg Pro Gly Arg Asn Thr Tyr Ser Asp Gln Lys Pro Pro Tyr 
1               5                   10                  15      


Ser Tyr Ile Ser Leu Thr Ala Met Ala Ile Gln Ser Ser Pro Glu Lys 
            20                  25                  30          


Met Leu Pro Leu Ser Glu Ile Tyr Lys Phe Ile Met Asp Arg Phe Pro 
        35                  40                  45              


Tyr Tyr Arg Glu Asn Thr Gln Arg Trp Gln Asn Ser Leu Arg His Asn 
    50                  55                  60                  


Leu Ser Phe Asn Asp Cys Phe Ile Lys Ile Pro Arg Arg Pro Asp Gln 
65                  70                  75                  80  


Pro Gly Lys Gly Ser Phe Trp Ala Leu His Pro Ser Cys Gly Asp Met 
                85                  90                  95      


Phe Glu Asn Gly Ser Phe Leu Arg Arg Arg Lys Arg Phe Lys Val Leu 
            100                 105                 110         


Lys Ser Asp His Leu Ala Pro Ser Lys Pro Ala Asp Ala Ala Gln Tyr 
        115                 120                 125             


Leu Gln Gln Gln Ala Lys Leu Arg Leu Ser Ala Leu Ala Ala Ser Gly 
    130                 135                 140                 


Thr His Leu Pro Gln Met Pro Ala Ala Ala Tyr Asn Leu Gly Gly Val 
145                 150                 155                 160 


Ala Gln Pro Ser Gly Phe Lys His Pro Phe Ala Ile Glu Asn Ile Ile 
                165                 170                 175     


Ala Arg Glu Tyr Lys Met Pro Gly Gly Leu Ala Phe Ser Ala Met Gln 
            180                 185                 190         


Pro Val Pro Ala Ala Tyr Pro Leu Pro Asn Gln Leu Thr Thr Met Gly 
        195                 200                 205             


Ser Ser Leu Gly Thr Gly Trp Pro His Val Tyr Gly Ser Ala Gly Met 
    210                 215                 220                 


Ile Asp Ser Ala Thr Pro Ile Ser Met Ala Ser Gly Asp Tyr Ser Ala 
225                 230                 235                 240 


Tyr Gly Val Pro Leu Lys Pro Leu Cys His Ala Ala Gly Gln Thr Leu 
                245                 250                 255     


Pro Ala Ile Pro Val Pro Ile Lys Pro Thr Pro Ala Ala Val Pro Ala 
            260                 265                 270         


Leu Pro Ala Leu Pro Ala Pro Ile Pro Thr Leu Leu Ser Asn Ser Pro 
        275                 280                 285             


Pro Ser Leu Ser Pro Thr Ser Ser Gln Thr Ala Thr Ser Gln Ser Ser 
    290                 295                 300                 


Pro Ala Thr Pro Ser Glu Thr Leu Thr Ser Pro Ala Ser Ala Leu His 
305                 310                 315                 320 


Ser Val Ala Val His 
                325 


<210>  3818
<211>  582
<212>  PRT
<213>  homo sapiens

<400>  3818

Met Ile Asn Ile Glu Ser Met Asp Thr Asp Lys Asp Asp Pro His Gly 
1               5                   10                  15      


Arg Leu Glu Tyr Thr Glu His Gln Gly Arg Ile Lys Asn Ala Arg Glu 
            20                  25                  30          


Ala His Ser Gln Ile Glu Lys Arg Arg Arg Asp Lys Met Asn Ser Phe 
        35                  40                  45              


Ile Asp Glu Leu Ala Ser Leu Val Pro Thr Cys Asn Ala Met Ser Arg 
    50                  55                  60                  


Lys Leu Asp Lys Leu Thr Val Leu Arg Met Ala Val Gln His Met Lys 
65                  70                  75                  80  


Thr Leu Arg Gly Ala Thr Asn Pro Tyr Thr Glu Ala Asn Tyr Lys Pro 
                85                  90                  95      


Thr Phe Leu Ser Asp Asp Glu Leu Lys His Leu Ile Leu Arg Ala Ala 
            100                 105                 110         


Asp Gly Phe Leu Phe Val Val Gly Cys Asp Arg Gly Lys Ile Leu Phe 
        115                 120                 125             


Val Ser Glu Ser Val Phe Lys Ile Leu Asn Tyr Ser Gln Asn Asp Leu 
    130                 135                 140                 


Ile Gly Gln Ser Leu Phe Asp Tyr Leu His Pro Lys Asp Ile Ala Lys 
145                 150                 155                 160 


Val Lys Glu Gln Leu Ser Ser Ser Asp Thr Ala Pro Arg Glu Arg Leu 
                165                 170                 175     


Ile Asp Ala Lys Thr Gly Leu Pro Val Lys Thr Asp Ile Thr Pro Gly 
            180                 185                 190         


Pro Ser Arg Leu Cys Ser Gly Ala Arg Arg Ser Phe Phe Cys Arg Met 
        195                 200                 205             


Lys Cys Asn Arg Pro Ser Val Lys Val Glu Asp Lys Asp Phe Pro Ser 
    210                 215                 220                 


Thr Cys Ser Lys Lys Lys Asp Arg Lys Ser Phe Cys Thr Ile His Ser 
225                 230                 235                 240 


Thr Gly Tyr Leu Lys Ser Trp Pro Pro Thr Lys Met Gly Leu Asp Glu 
                245                 250                 255     


Asp Asn Glu Pro Asp Asn Glu Gly Cys Asn Leu Ser Cys Leu Val Ala 
            260                 265                 270         


Ile Gly Arg Leu His Ser His Val Val Pro Gln Pro Val Asn Gly Glu 
        275                 280                 285             


Ile Arg Val Lys Ser Met Glu Tyr Val Ser Arg His Ala Ile Asp Gly 
    290                 295                 300                 


Lys Phe Val Phe Val Asp Gln Arg Ala Thr Ala Ile Leu Ala Tyr Leu 
305                 310                 315                 320 


Pro Gln Glu Leu Leu Gly Thr Ser Cys Tyr Glu Tyr Phe His Gln Asp 
                325                 330                 335     


Asp Ile Gly His Leu Ala Glu Cys His Arg Gln Val Leu Gln Thr Arg 
            340                 345                 350         


Glu Lys Ile Thr Thr Asn Cys Tyr Lys Phe Lys Ile Lys Asp Gly Ser 
        355                 360                 365             


Phe Ile Thr Leu Arg Ser Arg Trp Phe Ser Phe Met Asn Pro Trp Thr 
    370                 375                 380                 


Lys Glu Val Glu Tyr Ile Val Ser Thr Asn Thr Val Val Leu Ala Asn 
385                 390                 395                 400 


Val Leu Glu Gly Gly Asp Pro Thr Phe Pro Gln Leu Thr Ala Ser Pro 
                405                 410                 415     


His Ser Met Asp Ser Met Leu Pro Ser Gly Glu Gly Gly Pro Lys Arg 
            420                 425                 430         


Thr His Pro Thr Val Pro Gly Ile Pro Gly Gly Thr Arg Ala Gly Ala 
        435                 440                 445             


Gly Lys Ile Gly Arg Met Ile Ala Glu Glu Ile Met Glu Ile His Arg 
    450                 455                 460                 


Ile Arg Gly Ser Ser Pro Ser Ser Cys Gly Ser Ser Pro Leu Asn Ile 
465                 470                 475                 480 


Thr Ser Thr Pro Pro Pro Asp Ala Ser Ser Pro Gly Gly Lys Lys Ile 
                485                 490                 495     


Leu Asn Gly Gly Thr Pro Asp Ile Pro Ser Ser Gly Leu Leu Ser Gly 
            500                 505                 510         


Gln Ala Gln Glu Asn Pro Gly Tyr Pro Tyr Ser Asp Ser Ser Ser Ile 
        515                 520                 525             


Leu Gly Glu Asn Pro His Ile Gly Ile Asp Met Ile Asp Asn Asp Gln 
    530                 535                 540                 


Gly Ser Ser Ser Pro Ser Asn Asp Glu Ala Ala Met Ala Val Ile Met 
545                 550                 555                 560 


Ser Leu Leu Glu Ala Asp Ala Gly Leu Gly Gly Pro Val Asp Phe Ser 
                565                 570                 575     


Asp Leu Pro Trp Pro Leu 
            580         


<210>  3819
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  3819

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  3820
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  3820

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  3821
<211>  114
<212>  PRT
<213>  homo sapiens

<400>  3821

Met Ser Gln Ala Glu Leu Ser Thr Cys Ser Ala Pro Gln Thr Gln Arg 
1               5                   10                  15      


Ile Phe Gln Glu Ala Val Arg Lys Gly Asn Thr Gln Glu Leu Gln Ser 
            20                  25                  30          


Leu Leu Gln Asn Met Thr Asn Cys Glu Phe Asn Val Asn Ser Phe Gly 
        35                  40                  45              


Pro Glu Gly Gln Thr Ala Leu His Gln Ser Val Ile Asp Gly Asn Leu 
    50                  55                  60                  


Glu Leu Val Lys Leu Leu Val Lys Phe Gly Ala Asp Ile Arg Leu Ala 
65                  70                  75                  80  


Asn Arg Asp Gly Trp Ser Ala Leu His Ile Ala Ala Phe Gly Gly His 
                85                  90                  95      


Gln Asp Ile Val Leu Tyr Leu Ile Thr Lys Ala Lys Tyr Ala Ala Ser 
            100                 105                 110         


Gly Arg 
        


<210>  3822
<211>  270
<212>  PRT
<213>  homo sapiens

<400>  3822

Met Asn Pro Gln Cys Ala Arg Cys Gly Lys Val Val Tyr Pro Thr Glu 
1               5                   10                  15      


Lys Val Asn Cys Leu Asp Lys Tyr Trp His Lys Gly Cys Phe His Cys 
            20                  25                  30          


Glu Val Cys Lys Met Ala Leu Asn Met Asn Asn Tyr Lys Gly Tyr Glu 
        35                  40                  45              


Lys Lys Pro Tyr Cys Asn Ala His Tyr Pro Lys Gln Ser Phe Thr Thr 
    50                  55                  60                  


Val Ala Asp Thr Pro Glu Asn Leu Arg Leu Lys Gln Gln Ser Glu Leu 
65                  70                  75                  80  


Gln Ser Gln Val Lys Tyr Lys Arg Asp Phe Glu Glu Ser Lys Gly Arg 
                85                  90                  95      


Gly Phe Ser Ile Val Thr Asp Thr Pro Glu Leu Gln Arg Leu Lys Arg 
            100                 105                 110         


Thr Gln Glu Gln Ile Ser Asn Val Lys Tyr His Glu Asp Phe Glu Lys 
        115                 120                 125             


Thr Lys Gly Arg Gly Phe Thr Pro Val Val Asp Asp Pro Val Thr Glu 
    130                 135                 140                 


Arg Val Arg Lys Asn Thr Gln Val Val Ser Asp Ala Ala Tyr Lys Gly 
145                 150                 155                 160 


Val His Pro His Ile Val Glu Met Asp Arg Arg Pro Gly Ile Ile Val 
                165                 170                 175     


Ala Pro Val Leu Pro Gly Ala Tyr Gln Gln Ser His Ser Gln Gly Tyr 
            180                 185                 190         


Gly Tyr Met His Gln Thr Ser Val Ser Ser Met Arg Ser Met Gln His 
        195                 200                 205             


Ser Pro Asn Leu Arg Thr Tyr Arg Ala Met Tyr Asp Tyr Ser Ala Gln 
    210                 215                 220                 


Asp Glu Asp Glu Val Ser Phe Arg Asp Gly Asp Tyr Ile Val Asn Val 
225                 230                 235                 240 


Gln Pro Ile Asp Asp Gly Trp Met Tyr Gly Thr Val Gln Arg Thr Gly 
                245                 250                 255     


Arg Thr Gly Met Leu Pro Ala Asn Tyr Ile Glu Phe Val Asn 
            260                 265                 270 


<210>  3823
<211>  493
<212>  PRT
<213>  homo sapiens

<400>  3823

Met Thr Ala Asn Gly Thr Ala Glu Ala Val Gln Ile Gln Phe Gly Leu 
1               5                   10                  15      


Ile Asn Cys Gly Asn Lys Tyr Leu Thr Ala Glu Ala Phe Gly Phe Lys 
            20                  25                  30          


Val Asn Ala Ser Ala Ser Ser Leu Lys Lys Lys Gln Ile Trp Thr Leu 
        35                  40                  45              


Glu Gln Pro Pro Asp Glu Ala Gly Ser Ala Ala Val Cys Leu Arg Ser 
    50                  55                  60                  


His Leu Gly Arg Tyr Leu Ala Ala Asp Lys Asp Gly Asn Val Thr Cys 
65                  70                  75                  80  


Glu Arg Glu Val Pro Gly Pro Asp Cys Arg Phe Leu Ile Val Ala His 
                85                  90                  95      


Asp Asp Gly Arg Trp Ser Leu Gln Ser Glu Ala His Arg Arg Tyr Phe 
            100                 105                 110         


Gly Gly Thr Glu Asp Arg Leu Ser Cys Phe Ala Gln Thr Val Ser Pro 
        115                 120                 125             


Ala Glu Lys Trp Ser Val His Ile Ala Met His Pro Gln Val Asn Ile 
    130                 135                 140                 


Tyr Ser Val Thr Arg Lys Arg Tyr Ala His Leu Ser Ala Arg Pro Ala 
145                 150                 155                 160 


Asp Glu Ile Ala Val Asp Arg Asp Val Pro Trp Gly Val Asp Ser Leu 
                165                 170                 175     


Ile Thr Leu Ala Phe Gln Asp Gln Arg Tyr Ser Val Gln Thr Ala Asp 
            180                 185                 190         


His Arg Phe Leu Arg His Asp Gly Arg Leu Val Ala Arg Pro Glu Pro 
        195                 200                 205             


Ala Thr Gly Tyr Thr Leu Glu Phe Arg Ser Gly Lys Val Ala Phe Arg 
    210                 215                 220                 


Asp Cys Glu Gly Arg Tyr Leu Ala Pro Ser Gly Pro Ser Gly Thr Leu 
225                 230                 235                 240 


Lys Ala Gly Lys Ala Thr Lys Val Gly Lys Asp Glu Leu Phe Ala Leu 
                245                 250                 255     


Glu Gln Ser Cys Ala Gln Val Val Leu Gln Ala Ala Asn Glu Arg Asn 
            260                 265                 270         


Val Ser Thr Arg Gln Gly Met Asp Leu Ser Ala Asn Gln Asp Glu Glu 
        275                 280                 285             


Thr Asp Gln Glu Thr Phe Gln Leu Glu Ile Asp Arg Asp Thr Lys Lys 
    290                 295                 300                 


Cys Ala Phe Arg Thr His Thr Gly Lys Tyr Trp Thr Leu Thr Ala Thr 
305                 310                 315                 320 


Gly Gly Val Gln Ser Thr Ala Ser Ser Lys Asn Ala Ser Cys Tyr Phe 
                325                 330                 335     


Asp Ile Glu Trp Arg Asp Arg Arg Ile Thr Leu Arg Ala Ser Asn Gly 
            340                 345                 350         


Lys Phe Val Thr Ser Lys Lys Asn Gly Gln Leu Ala Ala Ser Val Glu 
        355                 360                 365             


Thr Ala Gly Asp Ser Glu Leu Phe Leu Met Lys Leu Ile Asn Arg Pro 
    370                 375                 380                 


Ile Ile Val Phe Arg Gly Glu His Gly Phe Ile Gly Cys Arg Lys Val 
385                 390                 395                 400 


Thr Gly Thr Leu Asp Ala Asn Arg Ser Ser Tyr Asp Val Phe Gln Leu 
                405                 410                 415     


Glu Phe Asn Asp Gly Ala Tyr Asn Ile Lys Asp Ser Thr Gly Lys Tyr 
            420                 425                 430         


Trp Thr Val Gly Ser Asp Ser Ala Val Thr Ser Ser Gly Asp Thr Pro 
        435                 440                 445             


Val Asp Phe Phe Phe Glu Phe Cys Asp Tyr Asn Lys Val Ala Ile Lys 
    450                 455                 460                 


Val Gly Gly Arg Tyr Leu Lys Gly Asp His Ala Gly Val Leu Lys Ala 
465                 470                 475                 480 


Ser Ala Glu Thr Val Asp Pro Ala Ser Leu Trp Glu Tyr 
                485                 490             


<210>  3824
<211>  533
<212>  PRT
<213>  homo sapiens

<400>  3824

Met Gly Pro Arg Gly Ala Ala Ser Leu Pro Arg Gly Pro Gly Pro Arg 
1               5                   10                  15      


Arg Leu Leu Leu Pro Val Val Leu Pro Leu Leu Leu Leu Leu Leu Leu 
            20                  25                  30          


Ala Pro Pro Gly Ser Gly Ala Gly Ala Ser Arg Pro Pro His Leu Val 
        35                  40                  45              


Phe Leu Leu Ala Asp Asp Leu Gly Trp Asn Asp Val Gly Phe His Gly 
    50                  55                  60                  


Ser Arg Ile Arg Thr Pro His Leu Asp Ala Leu Ala Ala Gly Gly Val 
65                  70                  75                  80  


Leu Leu Asp Asn Tyr Tyr Thr Gln Pro Leu Cys Thr Pro Ser Arg Ser 
                85                  90                  95      


Gln Leu Leu Thr Gly Arg Tyr Gln Ile Arg Thr Gly Leu Gln His Gln 
            100                 105                 110         


Ile Ile Trp Pro Cys Gln Pro Ser Cys Val Pro Leu Asp Glu Lys Leu 
        115                 120                 125             


Leu Pro Gln Leu Leu Lys Glu Ala Gly Tyr Thr Thr His Met Val Gly 
    130                 135                 140                 


Lys Trp His Leu Gly Met Tyr Arg Lys Glu Cys Leu Pro Thr Arg Arg 
145                 150                 155                 160 


Gly Phe Asp Thr Tyr Phe Gly Tyr Leu Leu Gly Ser Glu Asp Tyr Tyr 
                165                 170                 175     


Ser His Glu Arg Cys Thr Leu Ile Asp Ala Leu Asn Val Thr Arg Cys 
            180                 185                 190         


Ala Leu Asp Phe Arg Asp Gly Glu Glu Val Ala Thr Gly Tyr Lys Asn 
        195                 200                 205             


Met Tyr Ser Thr Asn Ile Phe Thr Lys Arg Ala Ile Ala Leu Ile Thr 
    210                 215                 220                 


Asn His Pro Pro Glu Lys Pro Leu Phe Leu Tyr Leu Ala Leu Gln Ser 
225                 230                 235                 240 


Val His Glu Pro Leu Gln Val Pro Glu Glu Tyr Leu Lys Pro Tyr Asp 
                245                 250                 255     


Phe Ile Gln Asp Lys Asn Arg His His Tyr Ala Gly Met Val Ser Leu 
            260                 265                 270         


Met Asp Glu Ala Val Gly Asn Val Thr Ala Ala Leu Lys Ser Ser Gly 
        275                 280                 285             


Leu Trp Asn Asn Thr Val Phe Ile Phe Ser Thr Asp Asn Gly Gly Gln 
    290                 295                 300                 


Thr Leu Ala Gly Gly Asn Asn Trp Pro Leu Arg Gly Arg Lys Trp Ser 
305                 310                 315                 320 


Leu Trp Glu Gly Gly Val Arg Gly Val Gly Phe Val Ala Ser Pro Leu 
                325                 330                 335     


Leu Lys Gln Lys Gly Val Lys Asn Arg Glu Leu Ile His Ile Ser Asp 
            340                 345                 350         


Trp Leu Pro Thr Leu Val Lys Leu Ala Arg Gly His Thr Asn Gly Thr 
        355                 360                 365             


Lys Pro Leu Asp Gly Phe Asp Val Trp Lys Thr Ile Ser Glu Gly Ser 
    370                 375                 380                 


Pro Ser Pro Arg Ile Glu Leu Leu His Asn Ile Asp Pro Asn Phe Val 
385                 390                 395                 400 


Asp Ser Ser Pro Cys Pro Arg Asn Ser Met Ala Pro Ala Lys Asp Asp 
                405                 410                 415     


Ser Ser Leu Pro Glu Tyr Ser Ala Phe Asn Thr Ser Val His Ala Ala 
            420                 425                 430         


Ile Arg His Gly Asn Trp Lys Leu Leu Thr Gly Tyr Pro Gly Cys Gly 
        435                 440                 445             


Tyr Trp Phe Pro Pro Pro Ser Gln Tyr Asn Val Ser Glu Ile Pro Ser 
    450                 455                 460                 


Ser Asp Pro Pro Thr Lys Thr Leu Trp Leu Phe Asp Ile Asp Arg Asp 
465                 470                 475                 480 


Pro Glu Glu Arg His Asp Leu Ser Arg Glu Tyr Pro His Ile Val Thr 
                485                 490                 495     


Lys Leu Leu Ser Arg Leu Gln Phe Tyr His Lys His Ser Val Pro Val 
            500                 505                 510         


Tyr Phe Pro Ala Gln Asp Pro Arg Cys Asp Pro Lys Ala Thr Gly Val 
        515                 520                 525             


Trp Gly Pro Trp Met 
    530             


<210>  3825
<211>  996
<212>  PRT
<213>  homo sapiens

<400>  3825

Met Gly Gly Ser Gln Ser Leu Gln Pro Ala Pro Ala Ser Asp Leu Asn 
1               5                   10                  15      


Leu Glu Ala Ser Glu Ala Met Ser Ser Asp Ser Glu Glu Ala Phe Glu 
            20                  25                  30          


Thr Pro Glu Ser Thr Thr Pro Val Lys Ala Pro Pro Ala Pro Pro Pro 
        35                  40                  45              


Pro Pro Pro Glu Val Ile Pro Glu Pro Glu Val Ser Thr Gln Pro Pro 
    50                  55                  60                  


Pro Glu Glu Pro Gly Cys Gly Ser Glu Thr Val Pro Val Pro Asp Gly 
65                  70                  75                  80  


Pro Arg Ser Asp Ser Val Glu Gly Ser Pro Phe Arg Pro Pro Ser His 
                85                  90                  95      


Ser Phe Ser Ala Val Phe Asp Glu Asp Lys Pro Ile Ala Ser Ser Gly 
            100                 105                 110         


Thr Tyr Asn Leu Asp Phe Asp Asn Ile Glu Leu Val Asp Thr Phe Gln 
        115                 120                 125             


Thr Leu Glu Pro Arg Ala Ser Asp Ala Lys Asn Gln Glu Gly Lys Val 
    130                 135                 140                 


Asn Thr Arg Arg Lys Ser Thr Asp Ser Val Pro Ile Ser Lys Ser Thr 
145                 150                 155                 160 


Leu Ser Arg Ser Leu Ser Leu Gln Ala Ser Asp Phe Asp Gly Ala Ser 
                165                 170                 175     


Ser Ser Gly Asn Pro Glu Ala Val Ala Leu Ala Pro Asp Ala Tyr Ser 
            180                 185                 190         


Thr Gly Ser Ser Ser Ala Ser Ser Thr Leu Lys Arg Thr Lys Lys Pro 
        195                 200                 205             


Arg Pro Pro Ser Leu Lys Lys Lys Gln Thr Thr Lys Lys Pro Thr Glu 
    210                 215                 220                 


Thr Pro Pro Val Lys Glu Thr Gln Gln Glu Pro Asp Glu Glu Ser Leu 
225                 230                 235                 240 


Val Pro Ser Gly Glu Asn Leu Ala Ser Glu Thr Lys Thr Glu Ser Ala 
                245                 250                 255     


Lys Thr Glu Gly Pro Ser Pro Ala Leu Leu Glu Glu Thr Pro Leu Glu 
            260                 265                 270         


Pro Ala Val Gly Pro Lys Ala Ala Cys Pro Leu Asp Ser Glu Ser Ala 
        275                 280                 285             


Glu Gly Val Val Pro Pro Ala Ser Gly Gly Gly Arg Val Gln Asn Ser 
    290                 295                 300                 


Pro Pro Val Gly Arg Lys Thr Leu Pro Leu Thr Thr Ala Pro Glu Ala 
305                 310                 315                 320 


Gly Glu Val Thr Pro Ser Asp Ser Gly Gly Gln Glu Asp Ser Pro Ala 
                325                 330                 335     


Lys Gly Leu Ser Val Arg Leu Glu Phe Asp Tyr Ser Glu Asp Lys Ser 
            340                 345                 350         


Ser Trp Asp Asn Gln Gln Glu Asn Pro Pro Pro Thr Lys Lys Ile Gly 
        355                 360                 365             


Lys Lys Pro Val Ala Lys Met Pro Leu Arg Arg Pro Lys Met Lys Lys 
    370                 375                 380                 


Thr Pro Glu Lys Leu Asp Asn Thr Pro Ala Ser Pro Pro Arg Ser Pro 
385                 390                 395                 400 


Ala Glu Pro Asn Asp Ile Pro Ile Ala Lys Gly Thr Tyr Thr Phe Asp 
                405                 410                 415     


Ile Asp Lys Trp Asp Asp Pro Asn Phe Asn Pro Phe Ser Ser Thr Ser 
            420                 425                 430         


Lys Met Gln Glu Ser Pro Lys Leu Pro Gln Gln Ser Tyr Asn Phe Asp 
        435                 440                 445             


Pro Asp Thr Cys Asp Glu Ser Val Asp Pro Phe Lys Thr Ser Ser Lys 
    450                 455                 460                 


Thr Pro Ser Ser Pro Ser Lys Ser Pro Ala Ser Phe Glu Ile Pro Ala 
465                 470                 475                 480 


Ser Ala Met Glu Ala Asn Gly Val Asp Gly Asp Gly Leu Asn Lys Pro 
                485                 490                 495     


Ala Lys Lys Lys Lys Thr Pro Leu Lys Thr Asp Thr Phe Arg Val Lys 
            500                 505                 510         


Lys Ser Pro Lys Arg Ser Pro Leu Ser Asp Pro Pro Ser Gln Asp Pro 
        515                 520                 525             


Thr Pro Ala Ala Thr Pro Glu Thr Pro Pro Val Ile Ser Ala Val Val 
    530                 535                 540                 


His Ala Thr Asp Glu Glu Lys Leu Ala Val Thr Asn Gln Lys Trp Thr 
545                 550                 555                 560 


Cys Met Thr Val Asp Leu Glu Ala Asp Lys Gln Asp Tyr Pro Gln Pro 
                565                 570                 575     


Ser Asp Leu Ser Thr Phe Val Asn Glu Thr Lys Phe Ser Ser Pro Thr 
            580                 585                 590         


Glu Glu Leu Asp Tyr Arg Asn Ser Tyr Glu Ile Glu Tyr Met Glu Lys 
        595                 600                 605             


Ile Gly Ser Ser Leu Pro Gln Asp Asp Asp Ala Pro Lys Lys Gln Ala 
    610                 615                 620                 


Leu Tyr Leu Met Phe Asp Thr Ser Gln Glu Ser Pro Val Lys Ser Ser 
625                 630                 635                 640 


Pro Val Arg Met Ser Glu Ser Pro Thr Pro Cys Ser Gly Ser Ser Phe 
                645                 650                 655     


Glu Glu Thr Glu Ala Leu Val Asn Thr Ala Ala Lys Asn Gln His Pro 
            660                 665                 670         


Val Pro Arg Gly Leu Ala Pro Asn Gln Glu Ser His Leu Gln Val Pro 
        675                 680                 685             


Glu Lys Ser Ser Gln Lys Glu Leu Glu Ala Met Gly Leu Gly Thr Pro 
    690                 695                 700                 


Ser Glu Ala Ile Glu Ile Thr Ala Pro Glu Gly Ser Phe Ala Ser Ala 
705                 710                 715                 720 


Asp Ala Leu Leu Ser Arg Leu Ala His Pro Val Ser Leu Cys Gly Ala 
                725                 730                 735     


Leu Asp Tyr Leu Glu Pro Asp Leu Ala Glu Lys Asn Pro Pro Leu Phe 
            740                 745                 750         


Ala Gln Lys Leu Gln Arg Glu Ala Ala His Pro Thr Asp Val Ser Ile 
        755                 760                 765             


Ser Lys Thr Ala Leu Tyr Ser Arg Ile Gly Thr Ala Glu Val Glu Lys 
    770                 775                 780                 


Pro Ala Gly Leu Leu Phe Gln Gln Pro Asp Leu Asp Ser Ala Leu Gln 
785                 790                 795                 800 


Ile Ala Arg Ala Glu Ile Ile Thr Lys Glu Arg Glu Val Ser Glu Trp 
                805                 810                 815     


Lys Asp Lys Tyr Glu Glu Ser Arg Arg Glu Val Met Glu Met Arg Lys 
            820                 825                 830         


Ile Val Ala Glu Tyr Glu Lys Thr Ile Ala Gln Met Ile Glu Asp Glu 
        835                 840                 845             


Gln Arg Glu Lys Ser Val Ser His Gln Thr Val Gln Gln Leu Val Leu 
    850                 855                 860                 


Glu Lys Glu Gln Ala Leu Ala Asp Leu Asn Ser Val Glu Lys Ser Leu 
865                 870                 875                 880 


Ala Asp Leu Phe Arg Arg Tyr Glu Lys Met Lys Glu Val Leu Glu Gly 
                885                 890                 895     


Phe Arg Lys Asn Glu Glu Val Leu Lys Arg Cys Ala Gln Glu Tyr Leu 
            900                 905                 910         


Ser Arg Val Lys Lys Glu Glu Gln Arg Tyr Gln Ala Leu Lys Val His 
        915                 920                 925             


Ala Glu Glu Lys Leu Asp Arg Ala Asn Ala Glu Ile Ala Gln Val Arg 
    930                 935                 940                 


Gly Lys Ala Gln Gln Glu Gln Ala Ala His Gln Ala Ser Leu Arg Lys 
945                 950                 955                 960 


Glu Gln Leu Arg Val Asp Ala Leu Glu Arg Thr Leu Glu Gln Lys Asn 
                965                 970                 975     


Lys Glu Ile Glu Glu Leu Thr Lys Ile Cys Asp Glu Leu Ile Ala Lys 
            980                 985                 990         


Met Gly Lys Ser 
        995     


<210>  3826
<211>  801
<212>  PRT
<213>  homo sapiens

<400>  3826

Met Lys Thr Ser Pro Arg Arg Pro Leu Ile Leu Lys Arg Arg Arg Leu 
1               5                   10                  15      


Pro Leu Pro Val Gln Asn Ala Pro Ser Glu Thr Ser Glu Glu Glu Pro 
            20                  25                  30          


Lys Arg Ser Pro Ala Gln Gln Glu Ser Asn Gln Ala Glu Ala Ser Lys 
        35                  40                  45              


Glu Val Ala Glu Ser Asn Ser Cys Lys Phe Pro Ala Gly Ile Lys Ile 
    50                  55                  60                  


Ile Asn His Pro Thr Met Pro Asn Thr Gln Val Val Ala Ile Pro Asn 
65                  70                  75                  80  


Asn Ala Asn Ile His Ser Ile Ile Thr Ala Leu Thr Ala Lys Gly Lys 
                85                  90                  95      


Glu Ser Gly Ser Ser Gly Pro Asn Lys Phe Ile Leu Ile Ser Cys Gly 
            100                 105                 110         


Gly Ala Pro Thr Gln Pro Pro Gly Leu Arg Pro Gln Thr Gln Thr Ser 
        115                 120                 125             


Tyr Asp Ala Lys Arg Thr Glu Val Thr Leu Glu Thr Leu Gly Pro Lys 
    130                 135                 140                 


Pro Ala Ala Arg Asp Val Asn Leu Pro Arg Pro Pro Gly Ala Leu Cys 
145                 150                 155                 160 


Glu Gln Lys Arg Glu Thr Cys Ala Asp Gly Glu Ala Ala Gly Cys Thr 
                165                 170                 175     


Ile Asn Asn Ser Leu Ser Asn Ile Gln Trp Leu Arg Lys Met Ser Ser 
            180                 185                 190         


Asp Gly Leu Gly Ser Arg Ser Ile Lys Gln Glu Met Glu Glu Lys Glu 
        195                 200                 205             


Asn Cys His Leu Glu Gln Arg Gln Val Lys Val Glu Glu Pro Ser Arg 
    210                 215                 220                 


Pro Ser Ala Ser Trp Gln Asn Ser Val Ser Glu Arg Pro Pro Tyr Ser 
225                 230                 235                 240 


Tyr Met Ala Met Ile Gln Phe Ala Ile Asn Ser Thr Glu Arg Lys Arg 
                245                 250                 255     


Met Thr Leu Lys Asp Ile Tyr Thr Trp Ile Glu Asp His Phe Pro Tyr 
            260                 265                 270         


Phe Lys His Ile Ala Lys Pro Gly Trp Lys Asn Ser Ile Arg His Asn 
        275                 280                 285             


Leu Ser Leu His Asp Met Phe Val Arg Glu Thr Ser Ala Asn Gly Lys 
    290                 295                 300                 


Val Ser Phe Trp Thr Ile His Pro Ser Ala Asn Arg Tyr Leu Thr Leu 
305                 310                 315                 320 


Asp Gln Val Phe Lys Pro Leu Asp Pro Gly Ser Pro Gln Leu Pro Glu 
                325                 330                 335     


His Leu Glu Ser Gln Gln Lys Arg Pro Asn Pro Glu Leu Arg Arg Asn 
            340                 345                 350         


Met Thr Ile Lys Thr Glu Leu Pro Leu Gly Ala Arg Arg Lys Met Lys 
        355                 360                 365             


Pro Leu Leu Pro Arg Val Ser Ser Tyr Leu Val Pro Ile Gln Phe Pro 
    370                 375                 380                 


Val Asn Gln Ser Leu Val Leu Gln Pro Ser Val Lys Val Pro Leu Pro 
385                 390                 395                 400 


Leu Ala Ala Ser Leu Met Ser Ser Glu Leu Ala Arg His Ser Lys Arg 
                405                 410                 415     


Val Arg Ile Ala Pro Lys Val Phe Gly Glu Gln Val Val Phe Gly Tyr 
            420                 425                 430         


Met Ser Lys Phe Phe Ser Gly Asp Leu Arg Asp Phe Gly Thr Pro Ile 
        435                 440                 445             


Thr Ser Leu Phe Asn Phe Ile Phe Leu Cys Leu Ser Val Leu Leu Ala 
    450                 455                 460                 


Glu Glu Gly Ile Ala Pro Leu Ser Ser Ala Gly Pro Gly Lys Glu Glu 
465                 470                 475                 480 


Lys Leu Leu Phe Gly Glu Gly Phe Ser Pro Leu Leu Pro Val Gln Thr 
                485                 490                 495     


Ile Lys Glu Glu Glu Ile Gln Pro Gly Glu Glu Met Pro His Leu Ala 
            500                 505                 510         


Arg Pro Ile Lys Val Glu Ser Pro Pro Leu Glu Glu Trp Pro Ser Pro 
        515                 520                 525             


Ala Pro Ser Phe Lys Glu Glu Ser Ser His Ser Trp Glu Asp Ser Ser 
    530                 535                 540                 


Gln Ser Pro Thr Pro Arg Pro Lys Lys Ser Tyr Ser Gly Leu Arg Ser 
545                 550                 555                 560 


Pro Thr Arg Cys Val Ser Glu Met Leu Val Ile Gln His Arg Glu Arg 
                565                 570                 575     


Arg Glu Arg Ser Arg Ser Arg Arg Lys Gln His Leu Leu Pro Pro Cys 
            580                 585                 590         


Val Asp Glu Pro Glu Leu Leu Phe Ser Glu Gly Pro Ser Thr Ser Arg 
        595                 600                 605             


Trp Ala Ala Glu Leu Pro Phe Pro Ala Asp Ser Ser Asp Pro Ala Ser 
    610                 615                 620                 


Gln Leu Ser Tyr Ser Gln Glu Val Gly Gly Pro Phe Lys Thr Pro Ile 
625                 630                 635                 640 


Lys Glu Thr Leu Pro Ile Ser Ser Thr Pro Ser Lys Ser Val Leu Pro 
                645                 650                 655     


Arg Thr Pro Glu Ser Trp Arg Leu Thr Pro Pro Ala Lys Val Gly Gly 
            660                 665                 670         


Leu Asp Phe Ser Pro Val Gln Thr Ser Gln Gly Ala Ser Asp Pro Leu 
        675                 680                 685             


Pro Asp Pro Leu Gly Leu Met Asp Leu Ser Thr Thr Pro Leu Gln Ser 
    690                 695                 700                 


Ala Pro Pro Leu Glu Ser Pro Gln Arg Leu Leu Ser Ser Glu Pro Leu 
705                 710                 715                 720 


Asp Leu Ile Ser Val Pro Phe Gly Asn Ser Ser Pro Ser Asp Ile Asp 
                725                 730                 735     


Val Pro Lys Pro Gly Ser Pro Glu Pro Gln Val Ser Gly Leu Ala Ala 
            740                 745                 750         


Asn Arg Ser Leu Thr Glu Gly Leu Val Leu Asp Thr Met Asn Asp Ser 
        755                 760                 765             


Leu Ser Lys Ile Leu Leu Asp Ile Ser Phe Pro Gly Leu Asp Glu Asp 
    770                 775                 780                 


Pro Leu Gly Pro Asp Asn Ile Asn Trp Ser Gln Phe Ile Pro Glu Leu 
785                 790                 795                 800 


Gln 
    


<210>  3827
<211>  594
<212>  PRT
<213>  homo sapiens

<400>  3827

Met Asn Gln Gly Ser Gly Leu Asp Leu Leu Lys Ile Ser Tyr Gly Lys 
1               5                   10                  15      


Gly Ala Arg Arg Lys Asn Arg Phe Lys Gly Ser Asp Gly Ser Thr Ser 
            20                  25                  30          


Ser Asp Thr Thr Ser Asn Ser Phe Val Arg Gln Gly Ser Ala Asp Ser 
        35                  40                  45              


Tyr Thr Ser Arg Pro Ser Asp Ser Asp Val Ser Leu Glu Glu Asp Arg 
    50                  55                  60                  


Glu Ala Val Arg Arg Glu Ala Glu Arg Gln Ala Gln Ala Gln Leu Glu 
65                  70                  75                  80  


Lys Ala Lys Thr Lys Pro Val Ala Phe Ala Val Arg Thr Asn Val Ser 
                85                  90                  95      


Tyr Ser Ala Ala His Glu Asp Asp Val Pro Val Pro Gly Met Ala Ile 
            100                 105                 110         


Ser Phe Glu Ala Lys Asp Phe Leu His Val Lys Glu Lys Phe Asn Asn 
        115                 120                 125             


Asp Trp Trp Ile Gly Arg Leu Val Lys Glu Gly Cys Glu Ile Gly Phe 
    130                 135                 140                 


Ile Pro Ser Pro Val Lys Leu Glu Asn Met Arg Leu Gln His Glu Gln 
145                 150                 155                 160 


Arg Ala Lys Gln Gly Lys Phe Tyr Ser Ser Lys Ser Gly Gly Asn Ser 
                165                 170                 175     


Ser Ser Ser Leu Gly Asp Ile Val Pro Ser Ser Arg Lys Ser Thr Pro 
            180                 185                 190         


Pro Ser Ser Ala Lys Gln Lys Gln Lys Ser Thr Glu His Thr Pro Pro 
        195                 200                 205             


Tyr Asp Val Val Pro Ser Met Arg Pro Val Val Leu Val Gly Pro Ser 
    210                 215                 220                 


Leu Lys Gly Tyr Glu Val Thr Asp Met Met Gln Lys Ala Leu Phe Asp 
225                 230                 235                 240 


Phe Leu Lys His Arg Phe Glu Gly Arg Ile Ser Ile Thr Arg Val Thr 
                245                 250                 255     


Ala Asp Ile Ser Leu Ala Lys Arg Ser Val Leu Asn Asn Pro Ser Lys 
            260                 265                 270         


His Ala Ile Ile Glu Arg Ser Asn Thr Arg Ser Ser Leu Ala Glu Val 
        275                 280                 285             


Gln Ser Glu Ile Glu Arg Ile Phe Glu Leu Ala Arg Thr Leu Gln Leu 
    290                 295                 300                 


Val Val Leu Asp Ala Asp Thr Ile Asn His Pro Ala Gln Leu Ser Lys 
305                 310                 315                 320 


Thr Ser Leu Ala Pro Ile Ile Val Tyr Val Lys Ile Ser Ser Pro Lys 
                325                 330                 335     


Val Leu Gln Arg Leu Ile Lys Ser Arg Gly Lys Ser Gln Ala Lys His 
            340                 345                 350         


Leu Asn Val Gln Met Val Ala Ala Asp Lys Leu Ala Gln Cys Pro Pro 
        355                 360                 365             


Glu Leu Phe Asp Val Ile Leu Asp Glu Asn Gln Leu Glu Asp Ala Cys 
    370                 375                 380                 


Glu His Leu Ala Asp Tyr Leu Glu Ala Tyr Trp Lys Ala Thr His Pro 
385                 390                 395                 400 


Pro Ser Ser Ser Leu Pro Asn Pro Leu Leu Ser Arg Thr Leu Ala Thr 
                405                 410                 415     


Ser Ser Leu Pro Leu Ser Pro Thr Leu Ala Ser Asn Ser Gln Gly Ser 
            420                 425                 430         


Gln Gly Asp Gln Arg Thr Asp Arg Ser Ala Pro Ile Arg Ser Ala Ser 
        435                 440                 445             


Gln Ala Glu Glu Glu Pro Ser Val Glu Pro Val Lys Lys Ser Gln His 
    450                 455                 460                 


Arg Ser Ser Ser Ser Ala Pro His His Asn His Arg Ser Gly Thr Ser 
465                 470                 475                 480 


Arg Gly Leu Ser Arg Gln Glu Thr Phe Asp Ser Glu Thr Gln Glu Ser 
                485                 490                 495     


Arg Asp Ser Ala Tyr Val Glu Pro Lys Glu Asp Tyr Ser His Asp His 
            500                 505                 510         


Val Asp His Tyr Ala Ser His Arg Asp His Asn His Arg Asp Glu Thr 
        515                 520                 525             


His Gly Ser Ser Asp His Arg His Arg Glu Ser Arg His Arg Ser Arg 
    530                 535                 540                 


Asp Val Asp Arg Glu Gln Asp His Asn Glu Cys Asn Lys Gln Arg Ser 
545                 550                 555                 560 


Arg His Lys Ser Lys Asp Arg Tyr Cys Glu Lys Asp Gly Glu Val Ile 
                565                 570                 575     


Ser Lys Lys Arg Asn Glu Ala Gly Glu Trp Asn Arg Asp Val Tyr Ile 
            580                 585                 590         


Arg Gln 
        


<210>  3828
<211>  479
<212>  PRT
<213>  homo sapiens

<400>  3828

Met Gly Ala Phe Leu Asp Lys Pro Lys Thr Glu Lys His Asn Ala His 
1               5                   10                  15      


Gly Ala Gly Asn Gly Leu Arg Tyr Gly Leu Ser Ser Met Gln Gly Trp 
            20                  25                  30          


Arg Val Glu Met Glu Asp Ala His Thr Ala Val Val Gly Ile Pro His 
        35                  40                  45              


Gly Leu Glu Asp Trp Ser Phe Phe Ala Val Tyr Asp Gly His Ala Gly 
    50                  55                  60                  


Ser Arg Val Ala Asn Tyr Cys Ser Thr His Leu Leu Glu His Ile Thr 
65                  70                  75                  80  


Thr Asn Glu Asp Phe Arg Ala Ala Gly Lys Ser Gly Ser Ala Leu Glu 
                85                  90                  95      


Leu Ser Val Glu Asn Val Lys Asn Gly Ile Arg Thr Gly Phe Leu Lys 
            100                 105                 110         


Ile Asp Glu Tyr Met Arg Asn Phe Ser Asp Leu Arg Asn Gly Met Asp 
        115                 120                 125             


Arg Ser Gly Ser Thr Ala Val Gly Val Met Ile Ser Pro Lys His Ile 
    130                 135                 140                 


Tyr Phe Ile Asn Cys Gly Asp Ser Arg Ala Val Leu Tyr Arg Asn Gly 
145                 150                 155                 160 


Gln Val Cys Phe Ser Thr Gln Asp His Lys Pro Cys Asn Pro Arg Glu 
                165                 170                 175     


Lys Glu Arg Ile Gln Asn Ala Gly Gly Ser Val Met Ile Gln Arg Val 
            180                 185                 190         


Asn Gly Ser Leu Ala Val Ser Arg Ala Leu Gly Asp Tyr Asp Tyr Lys 
        195                 200                 205             


Cys Val Asp Gly Lys Gly Pro Thr Glu Gln Leu Val Ser Pro Glu Pro 
    210                 215                 220                 


Glu Val Tyr Glu Ile Leu Arg Ala Glu Glu Asp Glu Phe Ile Ile Leu 
225                 230                 235                 240 


Ala Cys Asp Gly Ile Trp Asp Val Met Ser Asn Glu Glu Leu Cys Glu 
                245                 250                 255     


Tyr Val Lys Ser Arg Leu Glu Val Ser Asp Asp Leu Glu Asn Val Cys 
            260                 265                 270         


Asn Trp Val Val Asp Thr Cys Leu His Lys Gly Ser Arg Asp Asn Met 
        275                 280                 285             


Ser Ile Val Leu Val Cys Phe Ser Asn Ala Pro Lys Val Ser Asp Glu 
    290                 295                 300                 


Ala Val Lys Lys Asp Ser Glu Leu Asp Lys His Leu Glu Ser Arg Val 
305                 310                 315                 320 


Glu Glu Ile Met Glu Lys Ser Gly Glu Glu Gly Met Pro Asp Leu Ala 
                325                 330                 335     


His Val Met Arg Ile Leu Ser Ala Glu Asn Ile Pro Asn Leu Pro Pro 
            340                 345                 350         


Gly Gly Gly Leu Ala Gly Lys Arg Asn Val Ile Glu Ala Val Tyr Ser 
        355                 360                 365             


Arg Leu Asn Pro His Arg Glu Ser Asp Gly Ala Ser Asp Glu Ala Glu 
    370                 375                 380                 


Glu Ser Gly Ser Gln Gly Lys Leu Val Glu Ala Leu Arg Gln Met Arg 
385                 390                 395                 400 


Ile Asn His Arg Gly Asn Tyr Arg Gln Leu Leu Glu Glu Met Leu Thr 
                405                 410                 415     


Ser Tyr Arg Leu Ala Lys Val Glu Gly Glu Glu Ser Pro Ala Glu Pro 
            420                 425                 430         


Ala Ala Thr Ala Thr Ser Ser Asn Ser Asp Ala Gly Asn Pro Val Thr 
        435                 440                 445             


Met Gln Glu Ser His Thr Glu Ser Glu Ser Gly Leu Ala Glu Leu Asp 
    450                 455                 460                 


Ser Ser Asn Glu Asp Ala Gly Thr Lys Met Ser Gly Glu Lys Ile 
465                 470                 475                 


<210>  3829
<211>  1403
<212>  PRT
<213>  homo sapiens

<400>  3829

Met Val Ser Ser Gly Cys Arg Met Arg Ser Leu Trp Phe Ile Ile Val 
1               5                   10                  15      


Ile Ser Phe Leu Pro Asn Thr Glu Gly Phe Ser Arg Ala Ala Leu Pro 
            20                  25                  30          


Phe Gly Leu Val Arg Arg Glu Leu Ser Cys Glu Gly Tyr Ser Ile Asp 
        35                  40                  45              


Leu Arg Cys Pro Gly Ser Asp Val Ile Met Ile Glu Ser Ala Asn Tyr 
    50                  55                  60                  


Gly Arg Thr Asp Asp Lys Ile Cys Asp Ala Asp Pro Phe Gln Met Glu 
65                  70                  75                  80  


Asn Thr Asp Cys Tyr Leu Pro Asp Ala Phe Lys Ile Met Thr Gln Arg 
                85                  90                  95      


Cys Asn Asn Arg Thr Gln Cys Ile Val Val Thr Gly Ser Asp Val Phe 
            100                 105                 110         


Pro Asp Pro Cys Pro Gly Thr Tyr Lys Tyr Leu Glu Val Gln Tyr Glu 
        115                 120                 125             


Cys Val Pro Tyr Ile Phe Val Cys Pro Gly Thr Leu Lys Ala Ile Val 
    130                 135                 140                 


Asp Ser Pro Cys Ile Tyr Glu Ala Glu Gln Lys Ala Gly Ala Trp Cys 
145                 150                 155                 160 


Lys Asp Pro Leu Gln Ala Ala Asp Lys Ile Tyr Phe Met Pro Trp Thr 
                165                 170                 175     


Pro Tyr Arg Thr Asp Thr Leu Ile Glu Tyr Ala Ser Leu Glu Asp Phe 
            180                 185                 190         


Gln Asn Ser Arg Gln Thr Thr Thr Tyr Lys Leu Pro Asn Arg Val Asp 
        195                 200                 205             


Gly Thr Gly Phe Val Val Tyr Asp Gly Ala Val Phe Phe Asn Lys Glu 
    210                 215                 220                 


Arg Thr Arg Asn Ile Val Lys Phe Asp Leu Arg Thr Arg Ile Lys Ser 
225                 230                 235                 240 


Gly Glu Ala Ile Ile Asn Tyr Ala Asn Tyr His Asp Thr Ser Pro Tyr 
                245                 250                 255     


Arg Trp Gly Gly Lys Thr Asp Ile Asp Leu Ala Val Asp Glu Asn Gly 
            260                 265                 270         


Leu Trp Val Ile Tyr Ala Thr Glu Gln Asn Asn Gly Met Ile Val Ile 
        275                 280                 285             


Ser Gln Leu Asn Pro Tyr Thr Leu Arg Phe Glu Ala Thr Trp Glu Thr 
    290                 295                 300                 


Val Tyr Asp Lys Arg Ala Ala Ser Asn Ala Phe Met Ile Cys Gly Val 
305                 310                 315                 320 


Leu Tyr Val Val Arg Ser Val Tyr Gln Asp Asn Glu Ser Glu Thr Gly 
                325                 330                 335     


Lys Asn Ser Ile Asp Tyr Ile Tyr Asn Thr Arg Leu Asn Arg Gly Glu 
            340                 345                 350         


Tyr Val Asp Val Pro Phe Pro Asn Gln Tyr Gln Tyr Ile Ala Ala Val 
        355                 360                 365             


Asp Tyr Asn Pro Arg Asp Asn Gln Leu Tyr Val Trp Asn Asn Asn Phe 
    370                 375                 380                 


Ile Leu Arg Tyr Ser Leu Glu Phe Gly Pro Pro Asp Pro Ala Gln Val 
385                 390                 395                 400 


Pro Thr Thr Ala Val Thr Ile Thr Ser Ser Ala Glu Leu Phe Lys Thr 
                405                 410                 415     


Ile Ile Ser Thr Thr Ser Thr Thr Ser Gln Lys Gly Pro Met Ser Thr 
            420                 425                 430         


Thr Val Ala Gly Ser Gln Glu Gly Ser Lys Gly Thr Lys Pro Pro Pro 
        435                 440                 445             


Ala Val Ser Thr Thr Lys Ile Pro Pro Ile Thr Asn Ile Phe Pro Leu 
    450                 455                 460                 


Pro Glu Arg Phe Cys Glu Ala Leu Asp Ser Lys Gly Ile Lys Trp Pro 
465                 470                 475                 480 


Gln Thr Gln Arg Gly Met Met Val Glu Arg Pro Cys Pro Lys Gly Thr 
                485                 490                 495     


Arg Gly Thr Ala Ser Tyr Leu Cys Met Ile Ser Thr Gly Thr Trp Asn 
            500                 505                 510         


Pro Lys Gly Pro Asp Leu Ser Asn Cys Thr Ser His Trp Val Asn Gln 
        515                 520                 525             


Leu Ala Gln Lys Ile Arg Ser Gly Glu Asn Ala Ala Ser Leu Ala Asn 
    530                 535                 540                 


Glu Leu Ala Lys His Thr Lys Gly Pro Val Phe Ala Gly Asp Val Ser 
545                 550                 555                 560 


Ser Ser Val Arg Leu Met Glu Gln Leu Val Asp Ile Leu Asp Ala Gln 
                565                 570                 575     


Leu Gln Glu Leu Lys Pro Ser Glu Lys Asp Ser Ala Gly Arg Ser Tyr 
            580                 585                 590         


Asn Lys Ala Ile Val Asp Thr Val Asp Asn Leu Leu Arg Pro Glu Ala 
        595                 600                 605             


Leu Glu Ser Trp Lys His Met Asn Ser Ser Glu Gln Ala His Thr Ala 
    610                 615                 620                 


Thr Met Leu Leu Asp Thr Leu Glu Glu Gly Ala Phe Val Leu Ala Asp 
625                 630                 635                 640 


Asn Leu Leu Glu Pro Thr Arg Val Ser Met Pro Thr Glu Asn Ile Val 
                645                 650                 655     


Leu Glu Val Ala Val Leu Ser Thr Glu Gly Gln Ile Gln Asp Phe Lys 
            660                 665                 670         


Phe Pro Leu Gly Ile Lys Gly Ala Gly Ser Ser Ile Gln Leu Ser Ala 
        675                 680                 685             


Asn Thr Val Lys Gln Asn Ser Arg Asn Gly Leu Ala Lys Leu Val Phe 
    690                 695                 700                 


Ile Ile Tyr Arg Ser Leu Gly Gln Phe Leu Ser Thr Glu Asn Ala Thr 
705                 710                 715                 720 


Ile Lys Leu Gly Ala Asp Phe Ile Gly Arg Asn Ser Thr Ile Ala Val 
                725                 730                 735     


Asn Ser His Val Ile Ser Val Ser Ile Asn Lys Glu Ser Ser Arg Val 
            740                 745                 750         


Tyr Leu Thr Asp Pro Val Leu Phe Thr Leu Pro His Ile Asp Pro Asp 
        755                 760                 765             


Asn Tyr Phe Asn Ala Asn Cys Ser Phe Trp Asn Tyr Ser Glu Arg Thr 
    770                 775                 780                 


Met Met Gly Tyr Trp Ser Thr Gln Gly Cys Lys Leu Val Asp Thr Asn 
785                 790                 795                 800 


Lys Thr Arg Thr Thr Cys Ala Cys Ser His Leu Thr Asn Phe Ala Ile 
                805                 810                 815     


Leu Met Ala His Arg Glu Ile Ala Tyr Lys Asp Gly Val His Glu Leu 
            820                 825                 830         


Leu Leu Thr Val Ile Thr Trp Val Gly Ile Val Ile Ser Leu Val Cys 
        835                 840                 845             


Leu Ala Ile Cys Ile Phe Thr Phe Cys Phe Phe Arg Gly Leu Gln Ser 
    850                 855                 860                 


Asp Arg Asn Thr Ile His Lys Asn Leu Cys Ile Asn Leu Phe Ile Ala 
865                 870                 875                 880 


Glu Phe Ile Phe Leu Ile Gly Ile Asp Lys Thr Lys Tyr Ala Ile Ala 
                885                 890                 895     


Cys Pro Ile Phe Ala Gly Leu Leu His Phe Phe Phe Leu Ala Ala Phe 
            900                 905                 910         


Ala Trp Met Cys Leu Glu Gly Val Gln Leu Tyr Leu Met Leu Val Glu 
        915                 920                 925             


Val Phe Glu Ser Glu Tyr Ser Arg Lys Lys Tyr Tyr Tyr Val Ala Gly 
    930                 935                 940                 


Tyr Leu Phe Pro Ala Thr Val Val Gly Val Ser Ala Ala Ile Asp Tyr 
945                 950                 955                 960 


Lys Ser Tyr Gly Thr Glu Lys Ala Cys Trp Leu His Val Asp Asn Tyr 
                965                 970                 975     


Phe Ile Trp Ser Phe Ile Gly Pro Val Thr Phe Ile Ile Leu Leu Asn 
            980                 985                 990         


Ile Ile Phe Leu Val Ile Thr Leu  Cys Lys Met Val Lys  His Ser Asn 
        995                 1000                 1005             


Thr Leu  Lys Pro Asp Ser Ser  Arg Leu Glu Asn Ile  Lys Ser Trp 
    1010                 1015                 1020             


Val Leu  Gly Ala Phe Ala Leu  Leu Cys Leu Leu Gly  Leu Thr Trp 
    1025                 1030                 1035             


Ser Phe  Gly Leu Leu Phe Ile  Asn Glu Glu Thr Ile  Val Met Ala 
    1040                 1045                 1050             


Tyr Leu  Phe Thr Ile Phe Asn  Ala Phe Gln Gly Val  Phe Ile Phe 
    1055                 1060                 1065             


Ile Phe  His Cys Ala Leu Gln  Lys Lys Val Arg Lys  Glu Tyr Gly 
    1070                 1075                 1080             


Lys Cys  Phe Arg His Ser Tyr  Cys Cys Gly Gly Leu  Pro Thr Glu 
    1085                 1090                 1095             


Ser Pro  His Ser Ser Val Lys  Ala Ser Thr Thr Arg  Thr Ser Ala 
    1100                 1105                 1110             


Arg Tyr  Ser Ser Gly Thr Gln  Ser Arg Ile Arg Arg  Met Trp Asn 
    1115                 1120                 1125             


Asp Thr  Val Arg Lys Gln Ser  Glu Ser Ser Phe Ile  Ser Gly Asp 
    1130                 1135                 1140             


Ile Asn  Ser Thr Ser Thr Leu  Asn Gln Gly His Ser  Leu Asn Asn 
    1145                 1150                 1155             


Ala Arg  Asp Thr Ser Ala Met  Asp Thr Leu Pro Leu  Asn Gly Asn 
    1160                 1165                 1170             


Phe Asn  Asn Ser Tyr Ser Leu  His Lys Gly Asp Tyr  Asn Asp Ser 
    1175                 1180                 1185             


Val Gln  Val Val Asp Cys Gly  Leu Ser Leu Asn Asp  Thr Ala Phe 
    1190                 1195                 1200             


Glu Lys  Met Ile Ile Ser Glu  Leu Val His Asn Asn  Leu Arg Gly 
    1205                 1210                 1215             


Ser Ser  Lys Thr His Asn Leu  Glu Leu Thr Leu Pro  Val Lys Pro 
    1220                 1225                 1230             


Val Ile  Gly Gly Ser Ser Ser  Glu Asp Asp Ala Ile  Val Ala Asp 
    1235                 1240                 1245             


Ala Ser  Ser Leu Met His Ser  Asp Asn Pro Gly Leu  Glu Leu His 
    1250                 1255                 1260             


His Lys  Glu Leu Glu Ala Pro  Leu Ile Pro Gln Arg  Thr His Ser 
    1265                 1270                 1275             


Leu Leu  Tyr Gln Pro Gln Lys  Lys Val Lys Ser Glu  Gly Thr Asp 
    1280                 1285                 1290             


Ser Tyr  Val Ser Gln Leu Thr  Ala Glu Ala Glu Asp  His Leu Gln 
    1295                 1300                 1305             


Ser Pro  Asn Arg Asp Ser Leu  Tyr Thr Ser Met Pro  Asn Leu Arg 
    1310                 1315                 1320             


Asp Ser  Pro Tyr Pro Glu Ser  Ser Pro Asp Met Glu  Glu Asp Leu 
    1325                 1330                 1335             


Ser Pro  Ser Arg Arg Ser Glu  Asn Glu Asp Ile Tyr  Tyr Lys Ser 
    1340                 1345                 1350             


Met Pro  Asn Leu Gly Ala Gly  His Gln Leu Gln Met  Cys Tyr Gln 
    1355                 1360                 1365             


Ile Ser  Arg Gly Asn Ser Asp  Gly Tyr Ile Ile Pro  Ile Asn Lys 
    1370                 1375                 1380             


Glu Gly  Cys Ile Pro Glu Gly  Asp Val Arg Glu Gly  Gln Met Gln 
    1385                 1390                 1395             


Leu Val  Thr Ser Leu 
    1400             


<210>  3830
<211>  413
<212>  PRT
<213>  homo sapiens

<400>  3830

Met Gly Pro Arg Gly Ala Ala Ser Leu Pro Arg Gly Pro Gly Pro Arg 
1               5                   10                  15      


Arg Leu Leu Leu Pro Val Val Leu Pro Leu Leu Leu Leu Leu Leu Leu 
            20                  25                  30          


Ala Pro Pro Gly Ser Gly Ala Gly Ala Ser Arg Pro Pro His Leu Val 
        35                  40                  45              


Phe Leu Leu Ala Asp Asp Leu Gly Trp Asn Asp Val Gly Phe His Gly 
    50                  55                  60                  


Ser Arg Ile Arg Thr Pro His Leu Asp Ala Leu Ala Ala Gly Gly Val 
65                  70                  75                  80  


Leu Leu Asp Asn Tyr Tyr Thr Gln Pro Leu Cys Thr Pro Ser Arg Ser 
                85                  90                  95      


Gln Leu Leu Thr Gly Arg Tyr Gln Ile Arg Thr Gly Leu Gln His Gln 
            100                 105                 110         


Ile Ile Trp Pro Cys Gln Pro Ser Cys Val Pro Leu Asp Glu Lys Leu 
        115                 120                 125             


Leu Pro Gln Leu Leu Lys Glu Ala Gly Tyr Thr Thr His Met Val Gly 
    130                 135                 140                 


Lys Trp His Leu Gly Met Tyr Arg Lys Glu Cys Leu Pro Thr Arg Arg 
145                 150                 155                 160 


Gly Phe Asp Thr Tyr Phe Gly Tyr Leu Leu Gly Ser Glu Asp Tyr Tyr 
                165                 170                 175     


Ser His Glu Arg Cys Thr Leu Ile Asp Ala Leu Asn Val Thr Arg Cys 
            180                 185                 190         


Ala Leu Asp Phe Arg Asp Gly Glu Glu Val Ala Thr Gly Tyr Lys Asn 
        195                 200                 205             


Met Tyr Ser Thr Asn Ile Phe Thr Lys Arg Ala Ile Ala Leu Ile Thr 
    210                 215                 220                 


Asn His Pro Pro Glu Lys Pro Leu Phe Leu Tyr Leu Ala Leu Gln Ser 
225                 230                 235                 240 


Val His Glu Pro Leu Gln Val Pro Glu Glu Tyr Leu Lys Pro Tyr Asp 
                245                 250                 255     


Phe Ile Gln Asp Lys Asn Arg His His Tyr Ala Gly Met Val Ser Leu 
            260                 265                 270         


Met Asp Glu Ala Val Gly Asn Val Thr Ala Ala Leu Lys Ser Ser Gly 
        275                 280                 285             


Leu Trp Asn Asn Thr Val Phe Ile Phe Ser Thr Asp Asn Gly Gly Gln 
    290                 295                 300                 


Thr Leu Ala Gly Gly Asn Asn Trp Pro Leu Arg Gly Arg Lys Trp Ser 
305                 310                 315                 320 


Leu Trp Glu Gly Gly Val Arg Gly Val Gly Phe Val Ala Ser Pro Leu 
                325                 330                 335     


Leu Lys Gln Lys Gly Val Lys Asn Arg Glu Leu Ile His Ile Ser Asp 
            340                 345                 350         


Trp Leu Pro Thr Leu Val Lys Leu Ala Arg Gly His Thr Asn Gly Thr 
        355                 360                 365             


Lys Pro Leu Asp Gly Phe Asp Val Trp Lys Thr Ile Ser Glu Gly Ser 
    370                 375                 380                 


Pro Ser Pro Arg Ile Glu Leu Leu His Asn Ile Asp Pro Asn Phe Val 
385                 390                 395                 400 


Asp Ser Ser Pro Tyr Trp Pro Glu Cys Ser Leu Leu Leu 
                405                 410             


<210>  3831
<211>  239
<212>  PRT
<213>  homo sapiens

<400>  3831

Met Ala Ser Glu Glu Leu Ala Cys Lys Leu Glu Arg Arg Leu Arg Arg 
1               5                   10                  15      


Glu Glu Ala Glu Glu Ser Gly Pro Gln Leu Ala Pro Leu Gly Ala Pro 
            20                  25                  30          


Ala Pro Glu Pro Lys Pro Glu Pro Glu Pro Pro Ala Arg Ala Pro Thr 
        35                  40                  45              


Ala Ser Ala Asp Ala Glu Leu Ser Ala Gln Leu Ser Arg Arg Leu Asp 
    50                  55                  60                  


Ile Asn Glu Gly Ala Ala Arg Pro Arg Arg Cys Arg Val Phe Asn Pro 
65                  70                  75                  80  


Tyr Thr Glu Phe Pro Glu Phe Ser Arg Arg Leu Ile Lys Asp Leu Glu 
                85                  90                  95      


Ser Met Phe Lys Leu Tyr Asp Ala Gly Arg Asp Gly Phe Ile Asp Leu 
            100                 105                 110         


Met Glu Leu Lys Leu Met Met Glu Lys Leu Gly Ala Pro Gln Thr His 
        115                 120                 125             


Leu Gly Leu Lys Ser Met Ile Lys Glu Val Asp Glu Asp Phe Asp Gly 
    130                 135                 140                 


Lys Leu Ser Phe Arg Glu Phe Leu Leu Ile Phe His Lys Ala Ala Ala 
145                 150                 155                 160 


Gly Glu Leu Gln Glu Asp Ser Gly Leu Met Ala Leu Ala Lys Leu Ser 
                165                 170                 175     


Glu Ile Asp Val Ala Leu Glu Gly Val Lys Gly Ala Lys Asn Phe Phe 
            180                 185                 190         


Glu Ala Lys Val Gln Ala Leu Ser Ser Ala Ser Lys Phe Glu Ala Glu 
        195                 200                 205             


Leu Lys Ala Glu Gln Asp Glu Arg Lys Arg Glu Glu Glu Glu Arg Arg 
    210                 215                 220                 


Leu Arg Gln Ala Ala Phe Gln Lys Leu Lys Ala Asn Phe Asn Thr 
225                 230                 235                 


<210>  3832
<211>  998
<212>  PRT
<213>  homo sapiens

<400>  3832

Met Gly Pro Pro Leu Pro Leu Leu Leu Leu Leu Leu Leu Leu Leu Pro 
1               5                   10                  15      


Pro Arg Val Leu Pro Ala Ala Pro Ser Ser Val Pro Arg Gly Arg Gln 
            20                  25                  30          


Leu Pro Gly Arg Leu Asp Gly Val Phe Gly Arg Cys Gln Lys Val Pro 
        35                  40                  45              


Ala Met Asp Phe Tyr Arg Tyr Glu Val Ser Pro Val Ala Leu Gln Arg 
    50                  55                  60                  


Leu Arg Val Ala Leu Gln Lys Leu Ser Gly Thr Gly Phe Thr Trp Gln 
65                  70                  75                  80  


Asp Asp Tyr Thr Gln Tyr Val Met Asp Gln Glu Leu Ala Asp Leu Pro 
                85                  90                  95      


Lys Thr Tyr Leu Arg Arg Pro Glu Ala Ser Ser Pro Ala Arg Pro Ser 
            100                 105                 110         


Lys His Ser Val Gly Ser Glu Arg Arg Tyr Ser Arg Glu Gly Gly Ala 
        115                 120                 125             


Ala Leu Ala Asn Ala Leu Arg Arg His Leu Pro Phe Leu Glu Ala Leu 
    130                 135                 140                 


Ser Gln Ala Pro Ala Ser Asp Val Leu Ala Arg Thr His Thr Ala Gln 
145                 150                 155                 160 


Asp Arg Pro Pro Ala Glu Gly Asp Asp Arg Phe Ser Glu Ser Ile Leu 
                165                 170                 175     


Thr Tyr Val Ala His Thr Ser Ala Leu Thr Tyr Pro Pro Gly Ser Arg 
            180                 185                 190         


Thr Gln Leu Arg Glu Asp Leu Leu Pro Arg Thr Leu Gly Gln Leu Gln 
        195                 200                 205             


Pro Asp Glu Leu Ser Pro Lys Val Asp Ser Gly Val Asp Arg His His 
    210                 215                 220                 


Leu Met Ala Ala Leu Ser Ala Tyr Ala Ala Gln Arg Pro Pro Ala Pro 
225                 230                 235                 240 


Pro Gly Glu Gly Ser Leu Glu Pro Gln Tyr Leu Leu Arg Ala Pro Ser 
                245                 250                 255     


Arg Met Pro Arg Pro Leu Leu Ala Pro Ala Ala Pro Gln Lys Trp Pro 
            260                 265                 270         


Ser Pro Leu Gly Asp Ser Glu Asp Pro Ser Ser Thr Gly Asp Gly Ala 
        275                 280                 285             


Arg Ile His Thr Leu Leu Lys Asp Leu Gln Arg Gln Pro Ala Glu Val 
    290                 295                 300                 


Arg Gly Leu Ser Gly Leu Glu Leu Asp Gly Met Ala Glu Leu Met Ala 
305                 310                 315                 320 


Gly Leu Met Gln Gly Val Asp His Gly Val Ala Arg Gly Ser Pro Gly 
                325                 330                 335     


Arg Ala Ala Leu Gly Glu Ser Gly Glu Gln Ala Asp Gly Pro Lys Ala 
            340                 345                 350         


Thr Leu Arg Gly Asp Ser Phe Pro Asp Asp Gly Val Gln Asp Asp Asp 
        355                 360                 365             


Asp Arg Leu Tyr Gln Glu Val His Arg Leu Ser Ala Thr Leu Gly Gly 
    370                 375                 380                 


Leu Leu Gln Asp His Gly Ser Arg Leu Leu Pro Gly Ala Leu Pro Phe 
385                 390                 395                 400 


Ala Arg Pro Leu Asp Met Glu Arg Lys Lys Ser Glu His Pro Glu Ser 
                405                 410                 415     


Ser Leu Ser Ser Glu Glu Glu Thr Ala Gly Val Glu Asn Val Lys Ser 
            420                 425                 430         


Gln Thr Tyr Ser Lys Asp Leu Leu Gly Gln Gln Pro His Ser Glu Pro 
        435                 440                 445             


Gly Ala Ala Ala Phe Gly Glu Leu Gln Asn Gln Met Pro Gly Pro Ser 
    450                 455                 460                 


Lys Glu Glu Gln Ser Leu Pro Ala Gly Ala Gln Glu Ala Leu Ser Asp 
465                 470                 475                 480 


Gly Leu Gln Leu Glu Val Gln Pro Ser Glu Glu Glu Ala Arg Gly Tyr 
                485                 490                 495     


Ile Val Thr Asp Arg Asp Pro Leu Arg Pro Glu Glu Gly Arg Arg Leu 
            500                 505                 510         


Val Glu Asp Val Ala Arg Leu Leu Gln Val Pro Ser Ser Ala Phe Ala 
        515                 520                 525             


Asp Val Glu Val Leu Gly Pro Ala Val Thr Phe Lys Val Ser Ala Asn 
    530                 535                 540                 


Val Gln Asn Val Thr Thr Glu Asp Val Glu Lys Ala Thr Val Asp Asn 
545                 550                 555                 560 


Lys Asp Lys Leu Glu Glu Thr Ser Gly Leu Lys Ile Leu Gln Thr Gly 
                565                 570                 575     


Val Gly Ser Lys Ser Lys Leu Lys Phe Leu Pro Pro Gln Ala Glu Gln 
            580                 585                 590         


Glu Asp Ser Thr Lys Phe Ile Ala Leu Thr Leu Val Ser Leu Ala Cys 
        595                 600                 605             


Ile Leu Gly Val Leu Leu Ala Ser Gly Leu Ile Tyr Cys Leu Arg His 
    610                 615                 620                 


Ser Ser Gln His Arg Leu Lys Glu Lys Leu Ser Gly Leu Gly Gly Asp 
625                 630                 635                 640 


Pro Gly Ala Asp Ala Thr Ala Ala Tyr Gln Glu Leu Cys Arg Gln Arg 
                645                 650                 655     


Met Ala Thr Arg Pro Pro Asp Arg Pro Glu Gly Pro His Thr Ser Arg 
            660                 665                 670         


Ile Ser Ser Val Ser Ser Gln Phe Ser Asp Gly Pro Ile Pro Ser Pro 
        675                 680                 685             


Ser Ala Arg Ser Ser Ala Ser Ser Trp Ser Glu Glu Pro Val Gln Ser 
    690                 695                 700                 


Asn Met Asp Ile Ser Thr Gly His Met Ile Leu Ser Tyr Met Glu Asp 
705                 710                 715                 720 


His Leu Lys Asn Lys Asn Arg Leu Glu Lys Glu Trp Glu Ala Leu Cys 
                725                 730                 735     


Ala Tyr Gln Ala Glu Pro Asn Ser Ser Phe Val Ala Gln Arg Glu Glu 
            740                 745                 750         


Asn Val Pro Lys Asn Arg Ser Leu Ala Val Leu Thr Tyr Asp His Ser 
        755                 760                 765             


Arg Val Leu Leu Lys Ala Glu Asn Ser His Ser His Ser Asp Tyr Ile 
    770                 775                 780                 


Asn Ala Ser Pro Ile Met Asp His Asp Pro Arg Asn Pro Ala Tyr Ile 
785                 790                 795                 800 


Ala Thr Gln Gly Pro Leu Pro Ala Thr Val Ala Asp Phe Trp Gln Met 
                805                 810                 815     


Val Trp Glu Ser Gly Cys Val Val Ile Val Met Leu Thr Pro Leu Ala 
            820                 825                 830         


Glu Asn Gly Val Arg Gln Cys Tyr His Tyr Trp Pro Asp Glu Gly Ser 
        835                 840                 845             


Asn Leu Tyr His Ile Tyr Glu Val Asn Leu Val Ser Glu His Ile Trp 
    850                 855                 860                 


Cys Glu Asp Phe Leu Val Arg Ser Phe Tyr Leu Lys Asn Leu Gln Thr 
865                 870                 875                 880 


Asn Glu Thr Arg Thr Val Thr Gln Phe His Phe Leu Ser Trp Tyr Asp 
                885                 890                 895     


Arg Gly Val Pro Ser Ser Ser Arg Ser Leu Leu Asp Phe Arg Arg Lys 
            900                 905                 910         


Val Asn Lys Cys Tyr Arg Gly Arg Ser Cys Pro Ile Ile Val His Cys 
        915                 920                 925             


Ser Asp Gly Ala Gly Arg Ser Gly Thr Tyr Val Leu Ile Asp Met Val 
    930                 935                 940                 


Leu Asn Lys Met Ala Lys Gly Ala Lys Glu Ile Asp Ile Ala Ala Thr 
945                 950                 955                 960 


Leu Glu His Leu Arg Asp Gln Arg Pro Gly Met Val Gln Thr Lys Glu 
                965                 970                 975     


Gln Phe Glu Phe Ala Leu Thr Ala Val Ala Glu Glu Val Asn Ala Ile 
            980                 985                 990         


Leu Lys Ala Leu Pro Gln 
        995             


<210>  3833
<211>  490
<212>  PRT
<213>  homo sapiens

<400>  3833

Met Asn Gly Ala Leu Asp His Ser Asp Gln Pro Asp Pro Asp Ala Ile 
1               5                   10                  15      


Lys Met Phe Val Gly Gln Ile Pro Arg Ser Trp Ser Glu Lys Glu Leu 
            20                  25                  30          


Lys Glu Leu Phe Glu Pro Tyr Gly Ala Val Tyr Gln Ile Asn Val Leu 
        35                  40                  45              


Arg Asp Arg Ser Gln Asn Pro Pro Gln Ser Lys Gly Cys Cys Phe Val 
    50                  55                  60                  


Thr Phe Tyr Thr Arg Lys Ala Ala Leu Glu Ala Gln Asn Ala Leu His 
65                  70                  75                  80  


Asn Ile Lys Thr Leu Pro Gly Met His His Pro Ile Gln Met Lys Pro 
                85                  90                  95      


Ala Asp Ser Glu Lys Ser Asn Ala Val Glu Asp Arg Lys Leu Phe Ile 
            100                 105                 110         


Gly Met Val Ser Lys Lys Cys Asn Glu Asn Asp Ile Arg Val Met Phe 
        115                 120                 125             


Ser Pro Phe Gly Gln Ile Glu Glu Cys Arg Ile Leu Arg Gly Pro Asp 
    130                 135                 140                 


Gly Leu Ser Arg Gly Cys Ala Phe Val Thr Phe Ser Thr Arg Ala Met 
145                 150                 155                 160 


Ala Gln Asn Ala Ile Lys Ala Met His Gln Ser Gln Thr Met Glu Gly 
                165                 170                 175     


Cys Ser Ser Pro Ile Val Val Lys Phe Ala Asp Thr Gln Lys Asp Lys 
            180                 185                 190         


Glu Gln Arg Arg Leu Gln Gln Gln Leu Ala Gln Gln Met Gln Gln Leu 
        195                 200                 205             


Asn Thr Ala Thr Trp Gly Asn Leu Thr Gly Leu Gly Gly Leu Thr Pro 
    210                 215                 220                 


Gln Tyr Leu Ala Leu Leu Gln Gln Ala Thr Ser Ser Ser Asn Leu Gly 
225                 230                 235                 240 


Ala Phe Ser Gly Ile Gln Gln Met Ala Gly Met Asn Ala Leu Gln Leu 
                245                 250                 255     


Gln Asn Leu Ala Thr Leu Ala Ala Ala Ala Ala Ala Ala Gln Thr Ser 
            260                 265                 270         


Ala Thr Ser Thr Asn Ala Asn Pro Leu Ser Thr Thr Ser Ser Ala Leu 
        275                 280                 285             


Gly Ala Leu Thr Ser Pro Val Ala Ala Ser Thr Pro Asn Ser Thr Ala 
    290                 295                 300                 


Gly Ala Ala Met Asn Ser Leu Thr Ser Leu Gly Thr Leu Gln Gly Leu 
305                 310                 315                 320 


Ala Gly Ala Thr Val Gly Leu Asn Asn Ile Asn Ala Leu Ala Val Ala 
                325                 330                 335     


Gln Met Leu Ser Gly Met Ala Ala Leu Asn Gly Gly Leu Gly Ala Thr 
            340                 345                 350         


Gly Leu Thr Asn Gly Thr Ala Gly Thr Met Asp Ala Leu Thr Gln Ala 
        355                 360                 365             


Tyr Ser Gly Ile Gln Gln Tyr Ala Ala Ala Ala Leu Pro Thr Leu Tyr 
    370                 375                 380                 


Ser Gln Ser Leu Leu Gln Gln Gln Ser Ala Ala Gly Ser Gln Lys Glu 
385                 390                 395                 400 


Gly Pro Glu Gly Ala Asn Leu Phe Ile Tyr His Leu Pro Gln Glu Phe 
                405                 410                 415     


Gly Asp Gln Asp Ile Leu Gln Met Phe Met Pro Phe Gly Asn Val Ile 
            420                 425                 430         


Ser Ala Lys Val Phe Ile Asp Lys Gln Thr Asn Leu Ser Lys Cys Phe 
        435                 440                 445             


Gly Phe Val Ser Tyr Asp Asn Pro Val Ser Ala Gln Ala Ala Ile Gln 
    450                 455                 460                 


Ala Met Asn Gly Phe Gln Ile Gly Met Lys Arg Leu Lys Val Gln Leu 
465                 470                 475                 480 


Lys Arg Ser Lys Asn Asp Ser Lys Pro Tyr 
                485                 490 


<210>  3834
<211>  803
<212>  PRT
<213>  homo sapiens

<400>  3834

Met Thr Thr Ala Lys Glu Pro Ser Ala Ser Gly Lys Ser Val Gln Gln 
1               5                   10                  15      


Gln Glu Gln Glu Leu Val Gly Ser Asn Pro Pro Gln Arg Asn Trp Lys 
            20                  25                  30          


Gly Ile Ala Ile Ala Leu Leu Val Ile Leu Val Ile Cys Ser Leu Ile 
        35                  40                  45              


Val Thr Ser Val Ile Leu Leu Thr Pro Ala Glu Asp Asn Ser Leu Ser 
    50                  55                  60                  


Gln Lys Lys Lys Val Thr Val Glu Asp Leu Phe Ser Glu Asp Phe Lys 
65                  70                  75                  80  


Ile His Asp Pro Glu Ala Lys Trp Ile Ser Asp Thr Glu Phe Ile Tyr 
                85                  90                  95      


Arg Glu Gln Lys Gly Thr Val Arg Leu Trp Asn Val Glu Thr Asn Thr 
            100                 105                 110         


Ser Thr Val Leu Ile Glu Gly Lys Lys Ile Glu Ser Leu Arg Ala Ile 
        115                 120                 125             


Arg Tyr Glu Ile Ser Pro Asp Arg Glu Tyr Ala Leu Phe Ser Tyr Asn 
    130                 135                 140                 


Val Glu Pro Ile Tyr Gln His Ser Tyr Thr Gly Tyr Tyr Val Leu Ser 
145                 150                 155                 160 


Lys Ile Pro His Gly Asp Pro Gln Ser Leu Asp Pro Pro Glu Val Ser 
                165                 170                 175     


Asn Ala Lys Leu Gln Tyr Ala Gly Trp Gly Pro Lys Gly Gln Gln Leu 
            180                 185                 190         


Ile Phe Ile Phe Glu Asn Asn Ile Tyr Tyr Cys Ala His Val Gly Lys 
        195                 200                 205             


Gln Ala Ile Arg Val Val Ser Thr Gly Lys Glu Gly Val Ile Tyr Asn 
    210                 215                 220                 


Gly Leu Ser Asp Trp Leu Tyr Glu Glu Glu Ile Leu Lys Thr His Ile 
225                 230                 235                 240 


Ala His Trp Trp Ser Pro Asp Gly Thr Arg Leu Ala Tyr Ala Ala Ile 
                245                 250                 255     


Asn Asp Ser Arg Val Pro Ile Met Glu Leu Pro Thr Tyr Thr Gly Ser 
            260                 265                 270         


Ile Tyr Pro Thr Val Lys Pro Tyr His Tyr Pro Lys Ala Gly Ser Glu 
        275                 280                 285             


Asn Pro Ser Ile Ser Leu His Val Ile Gly Leu Asn Gly Pro Thr His 
    290                 295                 300                 


Asp Leu Glu Met Met Pro Pro Asp Asp Pro Arg Met Arg Glu Tyr Tyr 
305                 310                 315                 320 


Ile Thr Met Val Lys Trp Ala Thr Ser Thr Lys Val Ala Val Thr Trp 
                325                 330                 335     


Leu Asn Arg Ala Gln Asn Val Ser Ile Leu Thr Leu Cys Asp Ala Thr 
            340                 345                 350         


Thr Gly Val Cys Thr Lys Lys His Glu Asp Glu Ser Glu Ala Trp Leu 
        355                 360                 365             


His Arg Gln Asn Glu Glu Pro Val Phe Ser Lys Asp Gly Arg Lys Phe 
    370                 375                 380                 


Phe Phe Ile Arg Ala Ile Pro Gln Gly Gly Arg Gly Lys Phe Tyr His 
385                 390                 395                 400 


Ile Thr Val Ser Ser Ser Gln Pro Asn Ser Ser Asn Asp Asn Ile Gln 
                405                 410                 415     


Ser Ile Thr Ser Gly Asp Trp Asp Val Thr Lys Ile Leu Ala Tyr Asp 
            420                 425                 430         


Glu Lys Gly Asn Lys Ile Tyr Phe Leu Ser Thr Glu Asp Leu Pro Arg 
        435                 440                 445             


Arg Arg Gln Leu Tyr Ser Ala Asn Thr Val Gly Asn Phe Asn Arg Gln 
    450                 455                 460                 


Cys Leu Ser Cys Asp Leu Val Glu Asn Cys Thr Tyr Phe Ser Ala Ser 
465                 470                 475                 480 


Phe Ser His Ser Met Asp Phe Phe Leu Leu Lys Cys Glu Gly Pro Gly 
                485                 490                 495     


Val Pro Met Val Thr Val His Asn Thr Thr Asp Lys Lys Lys Met Phe 
            500                 505                 510         


Asp Leu Glu Thr Asn Glu His Val Lys Lys Ala Ile Asn Asp Arg Gln 
        515                 520                 525             


Met Pro Lys Val Glu Tyr Arg Asp Ile Glu Ile Asp Asp Tyr Asn Leu 
    530                 535                 540                 


Pro Met Gln Ile Leu Lys Pro Ala Thr Phe Thr Asp Thr Thr His Tyr 
545                 550                 555                 560 


Pro Leu Leu Leu Val Val Asp Gly Thr Pro Gly Ser Gln Ser Val Ala 
                565                 570                 575     


Glu Lys Phe Glu Val Ser Trp Glu Thr Val Met Val Ser Ser His Gly 
            580                 585                 590         


Ala Val Val Val Lys Cys Asp Gly Arg Gly Ser Gly Phe Gln Gly Thr 
        595                 600                 605             


Lys Leu Leu His Glu Val Arg Arg Arg Leu Gly Leu Leu Glu Glu Lys 
    610                 615                 620                 


Asp Gln Met Glu Ala Val Arg Thr Met Leu Lys Glu Gln Tyr Ile Asp 
625                 630                 635                 640 


Arg Thr Arg Val Ala Val Phe Gly Lys Asp Tyr Gly Gly Tyr Leu Ser 
                645                 650                 655     


Thr Tyr Ile Leu Pro Ala Lys Gly Glu Asn Gln Gly Gln Thr Phe Thr 
            660                 665                 670         


Cys Gly Ser Ala Leu Ser Pro Ile Thr Asp Phe Lys Leu Tyr Ala Ser 
        675                 680                 685             


Ala Phe Ser Glu Arg Tyr Leu Gly Leu His Gly Leu Asp Asn Arg Ala 
    690                 695                 700                 


Tyr Glu Met Thr Lys Val Ala His Arg Val Ser Ala Leu Glu Glu Gln 
705                 710                 715                 720 


Gln Phe Leu Ile Ile His Pro Thr Ala Asp Glu Lys Ile His Phe Gln 
                725                 730                 735     


His Thr Ala Glu Leu Ile Thr Gln Leu Ile Arg Gly Lys Ala Asn Tyr 
            740                 745                 750         


Ser Leu Gln Ile Tyr Pro Asp Glu Ser His Tyr Phe Thr Ser Ser Ser 
        755                 760                 765             


Leu Lys Gln His Leu Tyr Arg Ser Ile Ile Asn Phe Phe Val Glu Cys 
    770                 775                 780                 


Phe Arg Ile Gln Asp Lys Leu Leu Thr Val Thr Ala Lys Glu Asp Glu 
785                 790                 795                 800 


Glu Glu Asp 
            


<210>  3835
<211>  212
<212>  PRT
<213>  homo sapiens

<400>  3835

Met Lys Ala Thr Ile Ile Leu Leu Leu Leu Ala Gln Val Ser Trp Ala 
1               5                   10                  15      


Gly Pro Phe Gln Gln Arg Gly Leu Phe Asp Phe Met Leu Glu Asp Glu 
            20                  25                  30          


Ala Ser Gly Ile Gly Pro Glu Val Pro Asp Asp Arg Asp Phe Glu Pro 
        35                  40                  45              


Ser Leu Gly Pro Val Cys Pro Phe Arg Cys Gln Cys His Leu Arg Val 
    50                  55                  60                  


Val Gln Cys Ser Asp Leu Gly Leu Pro Pro Ser Leu Thr Glu Leu His 
65                  70                  75                  80  


Leu Asp Gly Asn Lys Ile Ser Arg Val Asp Ala Ala Ser Leu Lys Gly 
                85                  90                  95      


Leu Asn Asn Leu Ala Lys Leu Gly Leu Ser Phe Asn Ser Ile Ser Ala 
            100                 105                 110         


Val Asp Asn Gly Ser Leu Ala Asn Thr Pro His Leu Arg Glu Leu His 
        115                 120                 125             


Leu Asp Asn Asn Lys Leu Thr Arg Val Pro Gly Gly Leu Ala Glu His 
    130                 135                 140                 


Lys Tyr Ile Gln Val Val Tyr Leu His Asn Asn Asn Ile Ser Val Val 
145                 150                 155                 160 


Gly Ser Ser Asp Phe Cys Pro Pro Gly His Asn Thr Lys Lys Ala Ser 
                165                 170                 175     


Tyr Ser Gly Val Ser Leu Phe Ser Asn Pro Val Gln Tyr Trp Glu Ile 
            180                 185                 190         


Gln Pro Ser Thr Phe Arg Cys Val Tyr Val Arg Ser Ala Ile Gln Leu 
        195                 200                 205             


Gly Asn Tyr Lys 
    210         


<210>  3836
<211>  437
<212>  PRT
<213>  homo sapiens

<400>  3836

Met Leu Gln Asp Leu Ser Ala Ser Val Phe Phe Pro Pro Cys Ser Gln 
1               5                   10                  15      


His Arg Thr Leu Ala Gln Val Pro Asp Asn Asp Glu Gln Phe Val Pro 
            20                  25                  30          


Asp Tyr Gln Ala Glu Ser Leu Ala Phe His Gly Leu Pro Leu Lys Ile 
        35                  40                  45              


Lys Lys Glu Pro His Ser Pro Cys Ser Glu Ile Ser Ser Ala Cys Ser 
    50                  55                  60                  


Gln Glu Gln Pro Phe Lys Phe Ser Tyr Gly Glu Lys Cys Leu Tyr Asn 
65                  70                  75                  80  


Val Ser Ala Tyr Asp Gln Lys Pro Gln Val Gly Met Arg Pro Ser Asn 
                85                  90                  95      


Pro Pro Thr Pro Ser Ser Thr Pro Val Ser Pro Leu His His Ala Ser 
            100                 105                 110         


Pro Asn Ser Thr His Thr Pro Lys Pro Asp Arg Ala Phe Pro Ala His 
        115                 120                 125             


Leu Pro Pro Ser Gln Ser Ile Pro Asp Ser Ser Tyr Pro Met Asp His 
    130                 135                 140                 


Arg Phe Arg Arg Gln Leu Ser Glu Pro Cys Asn Ser Phe Pro Pro Leu 
145                 150                 155                 160 


Pro Thr Met Pro Arg Glu Gly Arg Pro Met Tyr Gln Arg Gln Met Ser 
                165                 170                 175     


Glu Pro Asn Ile Pro Phe Pro Pro Gln Gly Phe Lys Gln Glu Tyr His 
            180                 185                 190         


Asp Pro Val Tyr Glu His Asn Thr Met Val Gly Ser Ala Ala Ser Gln 
        195                 200                 205             


Ser Phe Pro Pro Pro Leu Met Ile Lys Gln Glu Pro Arg Asp Phe Ala 
    210                 215                 220                 


Tyr Asp Ser Glu Val Pro Ser Cys His Ser Ile Tyr Met Arg Gln Glu 
225                 230                 235                 240 


Gly Phe Leu Ala His Pro Ser Arg Thr Glu Gly Cys Met Phe Glu Lys 
                245                 250                 255     


Gly Pro Arg Gln Phe Tyr Asp Asp Thr Cys Val Val Pro Glu Lys Phe 
            260                 265                 270         


Asp Gly Asp Ile Lys Gln Glu Pro Gly Met Tyr Arg Glu Gly Pro Thr 
        275                 280                 285             


Tyr Gln Arg Arg Gly Ser Leu Gln Leu Trp Gln Phe Leu Val Ala Leu 
    290                 295                 300                 


Leu Asp Asp Pro Ser Asn Ser His Phe Ile Ala Trp Thr Gly Arg Gly 
305                 310                 315                 320 


Met Glu Phe Lys Leu Ile Glu Pro Glu Glu Val Ala Arg Arg Trp Gly 
                325                 330                 335     


Ile Gln Lys Asn Arg Pro Ala Met Asn Tyr Asp Lys Leu Ser Arg Ser 
            340                 345                 350         


Leu Arg Tyr Tyr Tyr Glu Lys Gly Ile Met Gln Lys Val Ala Gly Glu 
        355                 360                 365             


Arg Tyr Val Tyr Lys Phe Val Cys Asp Pro Glu Ala Leu Phe Ser Met 
    370                 375                 380                 


Ala Phe Pro Asp Asn Gln Arg Pro Leu Leu Lys Thr Asp Met Glu Arg 
385                 390                 395                 400 


His Ile Asn Glu Glu Asp Thr Val Pro Leu Ser His Phe Asp Glu Ser 
                405                 410                 415     


Met Ala Tyr Met Pro Glu Gly Gly Cys Cys Asn Pro His Pro Tyr Asn 
            420                 425                 430         


Glu Gly Tyr Val Tyr 
        435         


<210>  3837
<211>  883
<212>  PRT
<213>  homo sapiens

<400>  3837

Met Gln Lys Ile Met His Ile Ser Val Leu Leu Ser Pro Val Leu Trp 
1               5                   10                  15      


Gly Leu Ile Phe Gly Val Ser Ser Asn Ser Ile Gln Ile Gly Gly Leu 
            20                  25                  30          


Phe Pro Arg Gly Ala Asp Gln Glu Tyr Ser Ala Phe Arg Val Gly Met 
        35                  40                  45              


Val Gln Phe Ser Thr Ser Glu Phe Arg Leu Thr Pro His Ile Asp Asn 
    50                  55                  60                  


Leu Glu Val Ala Asn Ser Phe Ala Val Thr Asn Ala Phe Cys Ser Gln 
65                  70                  75                  80  


Phe Ser Arg Gly Val Tyr Ala Ile Phe Gly Phe Tyr Asp Lys Lys Ser 
                85                  90                  95      


Val Asn Thr Ile Thr Ser Phe Cys Gly Thr Leu His Val Ser Phe Ile 
            100                 105                 110         


Thr Pro Ser Phe Pro Thr Asp Gly Thr His Pro Phe Val Ile Gln Met 
        115                 120                 125             


Arg Pro Asp Leu Lys Gly Ala Leu Leu Ser Leu Ile Glu Tyr Tyr Gln 
    130                 135                 140                 


Trp Asp Lys Phe Ala Tyr Leu Tyr Asp Ser Asp Arg Gly Leu Ser Thr 
145                 150                 155                 160 


Leu Gln Ala Val Leu Asp Ser Ala Ala Glu Lys Lys Trp Gln Val Thr 
                165                 170                 175     


Ala Ile Asn Val Gly Asn Ile Asn Asn Asp Lys Lys Asp Glu Met Tyr 
            180                 185                 190         


Arg Ser Leu Phe Gln Asp Leu Glu Leu Lys Lys Glu Arg Arg Val Ile 
        195                 200                 205             


Leu Asp Cys Glu Arg Asp Lys Val Asn Asp Ile Val Asp Gln Val Ile 
    210                 215                 220                 


Thr Ile Gly Lys His Val Lys Gly Tyr His Tyr Ile Ile Ala Asn Leu 
225                 230                 235                 240 


Gly Phe Thr Asp Gly Asp Leu Leu Lys Ile Gln Phe Gly Gly Ala Asn 
                245                 250                 255     


Val Ser Gly Phe Gln Ile Val Asp Tyr Asp Asp Ser Leu Val Ser Lys 
            260                 265                 270         


Phe Ile Glu Arg Trp Ser Thr Leu Glu Glu Lys Glu Tyr Pro Gly Ala 
        275                 280                 285             


His Thr Thr Thr Ile Lys Tyr Thr Ser Ala Leu Thr Tyr Asp Ala Val 
    290                 295                 300                 


Gln Val Met Thr Glu Ala Phe Arg Asn Leu Arg Lys Gln Arg Ile Glu 
305                 310                 315                 320 


Ile Ser Arg Arg Gly Asn Ala Gly Asp Cys Leu Ala Asn Pro Ala Val 
                325                 330                 335     


Pro Trp Gly Gln Gly Val Glu Ile Glu Arg Ala Leu Lys Gln Val Gln 
            340                 345                 350         


Val Glu Gly Leu Ser Gly Asn Ile Lys Phe Asp Gln Asn Gly Lys Arg 
        355                 360                 365             


Ile Asn Tyr Thr Ile Asn Ile Met Glu Leu Lys Thr Asn Gly Pro Arg 
    370                 375                 380                 


Lys Ile Gly Tyr Trp Ser Glu Val Asp Lys Met Val Val Thr Leu Thr 
385                 390                 395                 400 


Glu Leu Pro Ser Gly Asn Asp Thr Ser Gly Leu Glu Asn Lys Thr Val 
                405                 410                 415     


Val Val Thr Thr Ile Leu Glu Ser Pro Tyr Val Met Met Lys Lys Asn 
            420                 425                 430         


His Glu Met Leu Glu Gly Asn Glu Arg Tyr Glu Gly Tyr Cys Val Asp 
        435                 440                 445             


Leu Ala Ala Glu Ile Ala Lys His Cys Gly Phe Lys Tyr Lys Leu Thr 
    450                 455                 460                 


Ile Val Gly Asp Gly Lys Tyr Gly Ala Arg Asp Ala Asp Thr Lys Ile 
465                 470                 475                 480 


Trp Asn Gly Met Val Gly Glu Leu Val Tyr Gly Lys Ala Asp Ile Ala 
                485                 490                 495     


Ile Ala Pro Leu Thr Ile Thr Leu Val Arg Glu Glu Val Ile Asp Phe 
            500                 505                 510         


Ser Lys Pro Phe Met Ser Leu Gly Ile Ser Ile Met Ile Lys Lys Pro 
        515                 520                 525             


Gln Lys Ser Lys Pro Gly Val Phe Ser Phe Leu Asp Pro Leu Ala Tyr 
    530                 535                 540                 


Glu Ile Trp Met Cys Ile Val Phe Ala Tyr Ile Gly Val Ser Val Val 
545                 550                 555                 560 


Leu Phe Leu Val Ser Arg Phe Ser Pro Tyr Glu Trp His Thr Glu Glu 
                565                 570                 575     


Phe Glu Asp Gly Arg Glu Thr Gln Ser Ser Glu Ser Thr Asn Glu Phe 
            580                 585                 590         


Gly Ile Phe Asn Ser Leu Trp Phe Ser Leu Gly Ala Phe Met Arg Gln 
        595                 600                 605             


Gly Cys Asp Ile Ser Pro Arg Ser Leu Ser Gly Arg Ile Val Gly Gly 
    610                 615                 620                 


Val Trp Trp Phe Phe Thr Leu Ile Ile Ile Ser Ser Tyr Thr Ala Asn 
625                 630                 635                 640 


Leu Ala Ala Phe Leu Thr Val Glu Arg Met Val Ser Pro Ile Glu Ser 
                645                 650                 655     


Ala Glu Asp Leu Ser Lys Gln Thr Glu Ile Ala Tyr Gly Thr Leu Asp 
            660                 665                 670         


Ser Gly Ser Thr Lys Glu Phe Phe Arg Arg Ser Lys Ile Ala Val Phe 
        675                 680                 685             


Asp Lys Met Trp Thr Tyr Met Arg Ser Ala Glu Pro Ser Val Phe Val 
    690                 695                 700                 


Arg Thr Thr Ala Glu Gly Val Ala Arg Val Arg Lys Ser Lys Gly Lys 
705                 710                 715                 720 


Tyr Ala Tyr Leu Leu Glu Ser Thr Met Asn Glu Tyr Ile Glu Gln Arg 
                725                 730                 735     


Lys Pro Cys Asp Thr Met Lys Val Gly Gly Asn Leu Asp Ser Lys Gly 
            740                 745                 750         


Tyr Gly Ile Ala Thr Pro Lys Gly Ser Ser Leu Arg Thr Pro Val Asn 
        755                 760                 765             


Leu Ala Val Leu Lys Leu Ser Glu Gln Gly Val Leu Asp Lys Leu Lys 
    770                 775                 780                 


Asn Lys Trp Trp Tyr Asp Lys Gly Glu Cys Gly Ala Lys Asp Ser Gly 
785                 790                 795                 800 


Ser Lys Glu Lys Thr Ser Ala Leu Ser Leu Ser Asn Val Ala Gly Val 
                805                 810                 815     


Phe Tyr Ile Leu Val Gly Gly Leu Gly Leu Ala Met Leu Val Ala Leu 
            820                 825                 830         


Ile Glu Phe Cys Tyr Lys Ser Arg Ala Glu Ala Lys Arg Met Lys Val 
        835                 840                 845             


Ala Lys Asn Ala Gln Asn Ile Asn Pro Ser Ser Ser Gln Asn Ser Gln 
    850                 855                 860                 


Asn Phe Ala Thr Tyr Lys Glu Gly Tyr Asn Val Tyr Gly Ile Glu Ser 
865                 870                 875                 880 


Val Lys Ile 
            


<210>  3838
<211>  1129
<212>  PRT
<213>  homo sapiens

<400>  3838

Met Arg Ser Ser Ala Ser Arg Leu Ser Ser Phe Ser Ser Arg Asp Ser 
1               5                   10                  15      


Leu Trp Asn Arg Met Pro Asp Gln Ile Ser Val Ser Glu Phe Ile Ala 
            20                  25                  30          


Glu Thr Thr Glu Asp Tyr Asn Ser Pro Thr Thr Ser Ser Phe Thr Thr 
        35                  40                  45              


Arg Leu His Asn Cys Arg Asn Thr Val Thr Leu Leu Glu Glu Ala Leu 
    50                  55                  60                  


Asp Gln Asp Arg Thr Ala Leu Gln Lys Val Lys Lys Ser Val Lys Ala 
65                  70                  75                  80  


Ile Tyr Asn Ser Gly Gln Asp His Val Gln Asn Glu Glu Asn Tyr Ala 
                85                  90                  95      


Gln Val Leu Asp Lys Phe Gly Ser Asn Phe Leu Ser Arg Asp Asn Pro 
            100                 105                 110         


Asp Leu Gly Thr Ala Phe Val Lys Phe Ser Thr Leu Thr Lys Glu Leu 
        115                 120                 125             


Ser Thr Leu Leu Lys Asn Leu Leu Gln Gly Leu Ser His Asn Val Ile 
    130                 135                 140                 


Phe Thr Leu Asp Ser Leu Leu Lys Gly Asp Leu Lys Gly Val Lys Gly 
145                 150                 155                 160 


Asp Leu Lys Lys Pro Phe Asp Lys Ala Trp Lys Asp Tyr Glu Thr Lys 
                165                 170                 175     


Phe Thr Lys Ile Glu Lys Glu Lys Arg Glu His Ala Lys Gln His Gly 
            180                 185                 190         


Met Ile Arg Thr Glu Ile Thr Gly Ala Glu Ile Ala Glu Glu Met Glu 
        195                 200                 205             


Lys Glu Arg Arg Leu Phe Gln Leu Gln Met Cys Glu Tyr Leu Ile Lys 
    210                 215                 220                 


Val Asn Glu Ile Lys Thr Lys Lys Gly Val Asp Leu Leu Gln Asn Leu 
225                 230                 235                 240 


Ile Lys Tyr Tyr His Ala Gln Cys Asn Phe Phe Gln Asp Gly Leu Lys 
                245                 250                 255     


Thr Ala Asp Lys Leu Lys Gln Tyr Ile Glu Lys Leu Ala Ala Asp Leu 
            260                 265                 270         


Tyr Asn Ile Lys Gln Thr Gln Asp Glu Glu Lys Lys Gln Leu Thr Ala 
        275                 280                 285             


Leu Arg Asp Leu Ile Lys Ser Ser Leu Gln Leu Asp Gln Lys Glu Asp 
    290                 295                 300                 


Ser Gln Ser Arg Gln Gly Gly Tyr Ser Met His Gln Leu Gln Gly Asn 
305                 310                 315                 320 


Lys Glu Tyr Gly Ser Glu Lys Lys Gly Tyr Leu Leu Lys Lys Ser Asp 
                325                 330                 335     


Gly Ile Arg Lys Val Trp Gln Arg Arg Lys Cys Ser Val Lys Asn Gly 
            340                 345                 350         


Ile Leu Thr Ile Ser His Ala Thr Ser Asn Arg Gln Pro Ala Lys Leu 
        355                 360                 365             


Asn Leu Leu Thr Cys Gln Val Lys Pro Asn Ala Glu Asp Lys Lys Ser 
    370                 375                 380                 


Phe Asp Leu Ile Ser His Asn Arg Thr Tyr His Phe Gln Ala Glu Asp 
385                 390                 395                 400 


Glu Gln Asp Tyr Val Ala Trp Ile Ser Val Leu Thr Asn Ser Lys Glu 
                405                 410                 415     


Glu Ala Leu Thr Met Ala Phe Arg Gly Glu Gln Ser Ala Gly Glu Asn 
            420                 425                 430         


Ser Leu Glu Asp Leu Thr Lys Ala Ile Ile Glu Asp Val Gln Arg Leu 
        435                 440                 445             


Pro Gly Asn Asp Ile Cys Cys Asp Cys Gly Ser Ser Glu Pro Thr Trp 
    450                 455                 460                 


Leu Ser Thr Asn Leu Gly Ile Leu Thr Cys Ile Glu Cys Ser Gly Ile 
465                 470                 475                 480 


His Arg Glu Met Gly Val His Ile Ser Arg Ile Gln Ser Leu Glu Leu 
                485                 490                 495     


Asp Lys Leu Gly Thr Ser Glu Leu Leu Leu Ala Lys Asn Val Gly Asn 
            500                 505                 510         


Asn Ser Phe Asn Asp Ile Met Glu Ala Asn Leu Pro Ser Pro Ser Pro 
        515                 520                 525             


Lys Pro Thr Pro Ser Ser Asp Met Thr Val Arg Lys Glu Tyr Ile Thr 
    530                 535                 540                 


Ala Lys Tyr Val Asp His Arg Phe Ser Arg Lys Thr Cys Ser Thr Ser 
545                 550                 555                 560 


Ser Ala Lys Leu Asn Glu Leu Leu Glu Ala Ile Lys Ser Arg Asp Leu 
                565                 570                 575     


Leu Ala Leu Ile Gln Val Tyr Ala Glu Gly Val Glu Leu Met Glu Pro 
            580                 585                 590         


Leu Leu Glu Pro Gly Gln Glu Leu Gly Glu Thr Ala Leu His Leu Ala 
        595                 600                 605             


Val Arg Thr Ala Asp Gln Thr Ser Leu His Leu Val Asp Phe Leu Val 
    610                 615                 620                 


Gln Asn Cys Gly Asn Leu Asp Lys Gln Thr Ala Leu Gly Asn Thr Val 
625                 630                 635                 640 


Leu His Tyr Cys Ser Met Tyr Ser Lys Pro Glu Cys Leu Lys Leu Leu 
                645                 650                 655     


Leu Arg Ser Lys Pro Thr Val Asp Ile Val Asn Gln Ala Gly Glu Thr 
            660                 665                 670         


Ala Leu Asp Ile Ala Lys Arg Leu Lys Ala Thr Gln Cys Glu Asp Leu 
        675                 680                 685             


Leu Ser Gln Ala Lys Ser Gly Lys Phe Asn Pro His Val His Val Glu 
    690                 695                 700                 


Tyr Glu Trp Asn Leu Arg Gln Glu Glu Ile Asp Glu Ser Asp Asp Asp 
705                 710                 715                 720 


Leu Asp Asp Lys Pro Ser Pro Ile Lys Lys Glu Arg Ser Pro Arg Pro 
                725                 730                 735     


Gln Ser Phe Cys His Ser Ser Ser Ile Ser Pro Gln Asp Lys Leu Ala 
            740                 745                 750         


Leu Pro Gly Phe Ser Thr Pro Arg Asp Lys Gln Arg Leu Ser Tyr Gly 
        755                 760                 765             


Ala Phe Thr Asn Gln Ile Phe Val Ser Thr Ser Thr Asp Ser Pro Thr 
    770                 775                 780                 


Ser Pro Thr Thr Glu Ala Pro Pro Leu Pro Pro Arg Asn Ala Gly Lys 
785                 790                 795                 800 


Gly Pro Thr Gly Pro Pro Ser Thr Leu Pro Leu Ser Thr Gln Thr Ser 
                805                 810                 815     


Ser Gly Ser Ser Thr Leu Ser Lys Lys Arg Pro Pro Pro Pro Pro Pro 
            820                 825                 830         


Gly His Lys Arg Thr Leu Ser Asp Pro Pro Ser Pro Leu Pro His Gly 
        835                 840                 845             


Pro Pro Asn Lys Gly Ala Val Pro Trp Gly Asn Asp Gly Gly Pro Ser 
    850                 855                 860                 


Ser Ser Ser Lys Thr Thr Asn Lys Phe Glu Gly Leu Ser Gln Gln Ser 
865                 870                 875                 880 


Ser Thr Ser Ser Ala Lys Thr Ala Leu Gly Pro Arg Val Leu Pro Lys 
                885                 890                 895     


Leu Pro Gln Lys Val Ala Leu Arg Lys Thr Asp His Leu Ser Leu Asp 
            900                 905                 910         


Lys Ala Thr Ile Pro Pro Glu Ile Phe Gln Lys Ser Ser Gln Leu Ala 
        915                 920                 925             


Glu Leu Pro Gln Lys Pro Pro Pro Gly Asp Leu Pro Pro Lys Pro Thr 
    930                 935                 940                 


Glu Leu Ala Pro Lys Pro Gln Ile Gly Asp Leu Pro Pro Lys Pro Gly 
945                 950                 955                 960 


Glu Leu Pro Pro Lys Pro Gln Leu Gly Asp Leu Pro Pro Lys Pro Gln 
                965                 970                 975     


Leu Ser Asp Leu Pro Pro Lys Pro Gln Met Lys Asp Leu Pro Pro Lys 
            980                 985                 990         


Pro Gln Leu Gly Asp Leu Leu Ala  Lys Ser Gln Thr Gly  Asp Val Ser 
        995                 1000                 1005             


Pro Lys  Ala Gln Gln Pro Ser  Glu Val Thr Leu Lys  Ser His Pro 
    1010                 1015                 1020             


Leu Asp  Leu Ser Pro Asn Val  Gln Ser Arg Asp Ala  Ile Gln Lys 
    1025                 1030                 1035             


Gln Ala  Ser Glu Asp Ser Asn  Asp Leu Thr Pro Thr  Leu Pro Glu 
    1040                 1045                 1050             


Thr Pro  Val Pro Leu Pro Arg  Lys Ile Asn Thr Gly  Lys Asn Lys 
    1055                 1060                 1065             


Val Arg  Arg Val Lys Thr Ile  Tyr Asp Cys Gln Ala  Asp Asn Asp 
    1070                 1075                 1080             


Asp Glu  Leu Thr Phe Ile Glu  Gly Glu Val Ile Ile  Val Thr Gly 
    1085                 1090                 1095             


Glu Glu  Asp Gln Glu Trp Trp  Ile Gly His Ile Glu  Gly Gln Pro 
    1100                 1105                 1110             


Glu Arg  Lys Gly Val Phe Pro  Val Ser Phe Val His  Ile Leu Ser 
    1115                 1120                 1125             


Asp 
    


<210>  3839
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  3839

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  3840
<211>  325
<212>  PRT
<213>  homo sapiens

<400>  3840

Met Thr Glu Arg Arg Arg Asp Glu Leu Ser Glu Glu Ile Asn Asn Leu 
1               5                   10                  15      


Arg Glu Lys Val Met Lys Gln Ser Glu Glu Asn Asn Asn Leu Gln Ser 
            20                  25                  30          


Gln Val Gln Lys Leu Thr Glu Glu Asn Thr Thr Leu Arg Glu Gln Val 
        35                  40                  45              


Glu Pro Thr Pro Glu Asp Glu Asp Asp Asp Ile Glu Leu Arg Gly Ala 
    50                  55                  60                  


Ala Ala Ala Ala Ala Pro Pro Pro Pro Ile Glu Glu Glu Cys Pro Glu 
65                  70                  75                  80  


Asp Leu Pro Glu Lys Phe Asp Gly Asn Pro Asp Met Leu Ala Pro Phe 
                85                  90                  95      


Met Ala Gln Cys Gln Ile Phe Met Glu Lys Ser Thr Arg Asp Phe Ser 
            100                 105                 110         


Val Asp Arg Val Arg Val Cys Phe Val Thr Ser Met Met Thr Gly Arg 
        115                 120                 125             


Ala Ala Arg Trp Ala Ser Ala Lys Leu Glu Arg Ser His Tyr Leu Met 
    130                 135                 140                 


His Asn Tyr Pro Ala Phe Met Met Glu Met Lys His Val Phe Glu Asp 
145                 150                 155                 160 


Pro Gln Arg Arg Glu Val Ala Lys Arg Lys Ile Arg Arg Leu Arg Gln 
                165                 170                 175     


Gly Met Gly Ser Val Ile Asp Tyr Ser Asn Ala Phe Gln Met Ile Ala 
            180                 185                 190         


Gln Asp Leu Asp Trp Asn Glu Pro Ala Leu Ile Asp Gln Tyr His Glu 
        195                 200                 205             


Gly Leu Ser Asp His Ile Gln Glu Glu Leu Ser His Leu Glu Val Ala 
    210                 215                 220                 


Lys Ser Leu Ser Ala Leu Ile Gly Gln Cys Ile His Ile Glu Arg Arg 
225                 230                 235                 240 


Leu Ala Arg Ala Ala Ala Ala Arg Lys Pro Arg Ser Pro Pro Arg Ala 
                245                 250                 255     


Leu Val Leu Pro His Ile Ala Ser His His Gln Val Asp Pro Thr Glu 
            260                 265                 270         


Pro Val Gly Gly Ala Arg Met Arg Leu Thr Gln Glu Glu Lys Glu Arg 
        275                 280                 285             


Arg Arg Lys Leu Asn Leu Cys Leu Tyr Cys Gly Thr Gly Gly His Tyr 
    290                 295                 300                 


Ala Asp Asn Cys Pro Ala Lys Ala Ser Lys Ser Ser Pro Ala Gly Asn 
305                 310                 315                 320 


Ser Pro Ala Pro Leu 
                325 


<210>  3841
<211>  519
<212>  PRT
<213>  homo sapiens

<400>  3841

Met Ser Pro Leu Trp Trp Gly Phe Leu Leu Ser Cys Leu Gly Cys Lys 
1               5                   10                  15      


Ile Leu Pro Gly Ala Gln Gly Gln Phe Pro Arg Val Cys Met Thr Val 
            20                  25                  30          


Asp Ser Leu Val Asn Lys Glu Cys Cys Pro Arg Leu Gly Ala Glu Ser 
        35                  40                  45              


Ala Asn Val Cys Gly Ser Gln Gln Gly Arg Gly Gln Cys Thr Glu Val 
    50                  55                  60                  


Arg Ala Asp Thr Arg Pro Trp Ser Gly Pro Tyr Ile Leu Arg Asn Gln 
65                  70                  75                  80  


Asp Asp Arg Glu Leu Trp Pro Arg Lys Phe Phe His Arg Thr Cys Lys 
                85                  90                  95      


Cys Thr Gly Asn Phe Ala Gly Tyr Asn Cys Gly Asp Cys Lys Phe Gly 
            100                 105                 110         


Trp Thr Gly Pro Asn Cys Glu Arg Lys Lys Pro Pro Val Ile Arg Gln 
        115                 120                 125             


Asn Ile His Ser Leu Ser Pro Gln Glu Arg Glu Gln Phe Leu Gly Ala 
    130                 135                 140                 


Leu Asp Leu Ala Lys Lys Arg Val His Pro Asp Tyr Val Ile Thr Thr 
145                 150                 155                 160 


Gln His Trp Leu Gly Leu Leu Gly Pro Asn Gly Thr Gln Pro Gln Phe 
                165                 170                 175     


Ala Asn Cys Ser Val Tyr Asp Phe Phe Val Trp Leu His Tyr Tyr Ser 
            180                 185                 190         


Val Arg Asp Thr Leu Leu Gly Pro Gly Arg Pro Tyr Arg Ala Ile Asp 
        195                 200                 205             


Phe Ser His Gln Gly Pro Ala Phe Val Thr Trp His Arg Tyr His Leu 
    210                 215                 220                 


Leu Cys Leu Glu Arg Asp Leu Gln Arg Leu Ile Gly Asn Glu Ser Phe 
225                 230                 235                 240 


Ala Leu Pro Tyr Trp Asn Phe Ala Thr Gly Arg Asn Glu Cys Asp Val 
                245                 250                 255     


Cys Thr Asp Gln Leu Phe Gly Ala Ala Arg Pro Asp Asp Pro Thr Leu 
            260                 265                 270         


Ile Ser Arg Asn Ser Arg Phe Ser Ser Trp Glu Thr Val Cys Asp Ser 
        275                 280                 285             


Leu Asp Asp Tyr Asn His Leu Val Thr Leu Cys Asn Gly Thr Tyr Glu 
    290                 295                 300                 


Gly Leu Leu Arg Arg Asn Gln Met Gly Arg Asn Ser Met Lys Leu Pro 
305                 310                 315                 320 


Thr Leu Lys Asp Ile Arg Asp Cys Leu Ser Leu Gln Lys Phe Asp Asn 
                325                 330                 335     


Pro Pro Phe Phe Gln Asn Ser Thr Phe Ser Phe Arg Asn Ala Leu Glu 
            340                 345                 350         


Gly Phe Asp Lys Ala Asp Gly Thr Leu Asp Ser Gln Val Met Ser Leu 
        355                 360                 365             


His Asn Leu Val His Ser Phe Leu Asn Gly Thr Asn Ala Leu Pro His 
    370                 375                 380                 


Ser Ala Ala Asn Asp Pro Ile Phe Val Val Leu His Ser Phe Thr Asp 
385                 390                 395                 400 


Ala Ile Phe Asp Glu Trp Met Lys Arg Phe Asn Pro Pro Ala Asp Ala 
                405                 410                 415     


Trp Pro Gln Glu Leu Ala Pro Ile Gly His Asn Arg Met Tyr Asn Met 
            420                 425                 430         


Val Pro Phe Phe Pro Pro Val Thr Asn Glu Glu Leu Phe Leu Thr Ser 
        435                 440                 445             


Asp Gln Leu Gly Tyr Ser Tyr Ala Ile Asp Leu Pro Val Ser Val Glu 
    450                 455                 460                 


Glu Thr Pro Gly Trp Pro Thr Thr Leu Leu Val Val Met Gly Thr Leu 
465                 470                 475                 480 


Val Ala Leu Val Gly Leu Phe Val Leu Leu Ala Phe Leu Gln Tyr Arg 
                485                 490                 495     


Arg Leu Arg Lys Gly Tyr Thr Pro Leu Met Glu Thr His Leu Ser Ser 
            500                 505                 510         


Lys Arg Tyr Thr Glu Glu Ala 
        515                 


<210>  3842
<211>  45
<212>  PRT
<213>  homo sapiens

<400>  3842

Met Ser Asp Lys Pro Asp Leu Ser Glu Val Glu Lys Phe Asp Arg Ser 
1               5                   10                  15      


Lys Leu Lys Lys Thr Asn Thr Glu Glu Lys Asn Thr Leu Pro Ser Lys 
            20                  25                  30          


Glu Thr Ile Gln Gln Glu Lys Glu Cys Val Gln Thr Ser 
        35                  40                  45  


<210>  3843
<211>  44
<212>  PRT
<213>  homo sapiens

<400>  3843

Met Ser Asp Lys Pro Asp Met Ala Glu Ile Glu Lys Phe Asp Lys Ser 
1               5                   10                  15      


Lys Leu Lys Lys Thr Glu Thr Gln Glu Lys Asn Pro Leu Pro Ser Lys 
            20                  25                  30          


Glu Thr Ile Glu Gln Glu Lys Gln Ala Gly Glu Ser 
        35                  40                  


<210>  3844
<211>  2201
<212>  PRT
<213>  homo sapiens

<400>  3844

Met Gly Ala Met Thr Gln Leu Leu Ala Gly Val Phe Leu Ala Phe Leu 
1               5                   10                  15      


Ala Leu Ala Thr Glu Gly Gly Val Leu Lys Lys Val Ile Arg His Lys 
            20                  25                  30          


Arg Gln Ser Gly Val Asn Ala Thr Leu Pro Glu Glu Asn Gln Pro Val 
        35                  40                  45              


Val Phe Asn His Val Tyr Asn Ile Lys Leu Pro Val Gly Ser Gln Cys 
    50                  55                  60                  


Ser Val Asp Leu Glu Ser Ala Ser Gly Glu Lys Asp Leu Ala Pro Pro 
65                  70                  75                  80  


Ser Glu Pro Ser Glu Ser Phe Gln Glu His Thr Val Asp Gly Glu Asn 
                85                  90                  95      


Gln Ile Val Phe Thr His Arg Ile Asn Ile Pro Arg Arg Ala Cys Gly 
            100                 105                 110         


Cys Ala Ala Ala Pro Asp Val Lys Glu Leu Leu Ser Arg Leu Glu Glu 
        115                 120                 125             


Leu Glu Asn Leu Val Ser Ser Leu Arg Glu Gln Cys Thr Ala Gly Ala 
    130                 135                 140                 


Gly Cys Cys Leu Gln Pro Ala Thr Gly Arg Leu Asp Thr Arg Pro Phe 
145                 150                 155                 160 


Cys Ser Gly Arg Gly Asn Phe Ser Thr Glu Gly Cys Gly Cys Val Cys 
                165                 170                 175     


Glu Pro Gly Trp Lys Gly Pro Asn Cys Ser Glu Pro Glu Cys Pro Gly 
            180                 185                 190         


Asn Cys His Leu Arg Gly Arg Cys Ile Asp Gly Gln Cys Ile Cys Asp 
        195                 200                 205             


Asp Gly Phe Thr Gly Glu Asp Cys Ser Gln Leu Ala Cys Pro Ser Asp 
    210                 215                 220                 


Cys Asn Asp Gln Gly Lys Cys Val Asn Gly Val Cys Ile Cys Phe Glu 
225                 230                 235                 240 


Gly Tyr Ala Gly Ala Asp Cys Ser Arg Glu Ile Cys Pro Val Pro Cys 
                245                 250                 255     


Ser Glu Glu His Gly Thr Cys Val Asp Gly Leu Cys Val Cys His Asp 
            260                 265                 270         


Gly Phe Ala Gly Asp Asp Cys Asn Lys Pro Leu Cys Leu Asn Asn Cys 
        275                 280                 285             


Tyr Asn Arg Gly Arg Cys Val Glu Asn Glu Cys Val Cys Asp Glu Gly 
    290                 295                 300                 


Phe Thr Gly Glu Asp Cys Ser Glu Leu Ile Cys Pro Asn Asp Cys Phe 
305                 310                 315                 320 


Asp Arg Gly Arg Cys Ile Asn Gly Thr Cys Tyr Cys Glu Glu Gly Phe 
                325                 330                 335     


Thr Gly Glu Asp Cys Gly Lys Pro Thr Cys Pro His Ala Cys His Thr 
            340                 345                 350         


Gln Gly Arg Cys Glu Glu Gly Gln Cys Val Cys Asp Glu Gly Phe Ala 
        355                 360                 365             


Gly Val Asp Cys Ser Glu Lys Arg Cys Pro Ala Asp Cys His Asn Arg 
    370                 375                 380                 


Gly Arg Cys Val Asp Gly Arg Cys Glu Cys Asp Asp Gly Phe Thr Gly 
385                 390                 395                 400 


Ala Asp Cys Gly Glu Leu Lys Cys Pro Asn Gly Cys Ser Gly His Gly 
                405                 410                 415     


Arg Cys Val Asn Gly Gln Cys Val Cys Asp Glu Gly Tyr Thr Gly Glu 
            420                 425                 430         


Asp Cys Ser Gln Leu Arg Cys Pro Asn Asp Cys His Ser Arg Gly Arg 
        435                 440                 445             


Cys Val Glu Gly Lys Cys Val Cys Glu Gln Gly Phe Lys Gly Tyr Asp 
    450                 455                 460                 


Cys Ser Asp Met Ser Cys Pro Asn Asp Cys His Gln His Gly Arg Cys 
465                 470                 475                 480 


Val Asn Gly Met Cys Val Cys Asp Asp Gly Tyr Thr Gly Glu Asp Cys 
                485                 490                 495     


Arg Asp Arg Gln Cys Pro Arg Asp Cys Ser Asn Arg Gly Leu Cys Val 
            500                 505                 510         


Asp Gly Gln Cys Val Cys Glu Asp Gly Phe Thr Gly Pro Asp Cys Ala 
        515                 520                 525             


Glu Leu Ser Cys Pro Asn Asp Cys His Gly Gln Gly Arg Cys Val Asn 
    530                 535                 540                 


Gly Gln Cys Val Cys His Glu Gly Phe Met Gly Lys Asp Cys Lys Glu 
545                 550                 555                 560 


Gln Arg Cys Pro Ser Asp Cys His Gly Gln Gly Arg Cys Val Asp Gly 
                565                 570                 575     


Gln Cys Ile Cys His Glu Gly Phe Thr Gly Leu Asp Cys Gly Gln His 
            580                 585                 590         


Ser Cys Pro Ser Asp Cys Asn Asn Leu Gly Gln Cys Val Ser Gly Arg 
        595                 600                 605             


Cys Ile Cys Asn Glu Gly Tyr Ser Gly Glu Asp Cys Ser Glu Val Ser 
    610                 615                 620                 


Pro Pro Lys Asp Leu Val Val Thr Glu Val Thr Glu Glu Thr Val Asn 
625                 630                 635                 640 


Leu Ala Trp Asp Asn Glu Met Arg Val Thr Glu Tyr Leu Val Val Tyr 
                645                 650                 655     


Thr Pro Thr His Glu Gly Gly Leu Glu Met Gln Phe Arg Val Pro Gly 
            660                 665                 670         


Asp Gln Thr Ser Thr Ile Ile Gln Glu Leu Glu Pro Gly Val Glu Tyr 
        675                 680                 685             


Phe Ile Arg Val Phe Ala Ile Leu Glu Asn Lys Lys Ser Ile Pro Val 
    690                 695                 700                 


Ser Ala Arg Val Ala Thr Tyr Leu Pro Ala Pro Glu Gly Leu Lys Phe 
705                 710                 715                 720 


Lys Ser Ile Lys Glu Thr Ser Val Glu Val Glu Trp Asp Pro Leu Asp 
                725                 730                 735     


Ile Ala Phe Glu Thr Trp Glu Ile Ile Phe Arg Asn Met Asn Lys Glu 
            740                 745                 750         


Asp Glu Gly Glu Ile Thr Lys Ser Leu Arg Arg Pro Glu Thr Ser Tyr 
        755                 760                 765             


Arg Gln Thr Gly Leu Ala Pro Gly Gln Glu Tyr Glu Ile Ser Leu His 
    770                 775                 780                 


Ile Val Lys Asn Asn Thr Arg Gly Pro Gly Leu Lys Arg Val Thr Thr 
785                 790                 795                 800 


Thr Arg Leu Asp Ala Pro Ser Gln Ile Glu Val Lys Asp Val Thr Asp 
                805                 810                 815     


Thr Thr Ala Leu Ile Thr Trp Phe Lys Pro Leu Ala Glu Ile Asp Gly 
            820                 825                 830         


Ile Glu Leu Thr Tyr Gly Ile Lys Asp Val Pro Gly Asp Arg Thr Thr 
        835                 840                 845             


Ile Asp Leu Thr Glu Asp Glu Asn Gln Tyr Ser Ile Gly Asn Leu Lys 
    850                 855                 860                 


Pro Asp Thr Glu Tyr Glu Val Ser Leu Ile Ser Arg Arg Gly Asp Met 
865                 870                 875                 880 


Ser Ser Asn Pro Ala Lys Glu Thr Phe Thr Thr Gly Leu Asp Ala Pro 
                885                 890                 895     


Arg Asn Leu Arg Arg Val Ser Gln Thr Asp Asn Ser Ile Thr Leu Glu 
            900                 905                 910         


Trp Arg Asn Gly Lys Ala Ala Ile Asp Ser Tyr Arg Ile Lys Tyr Ala 
        915                 920                 925             


Pro Ile Ser Gly Gly Asp His Ala Glu Val Asp Val Pro Lys Ser Gln 
    930                 935                 940                 


Gln Ala Thr Thr Lys Thr Thr Leu Thr Gly Leu Arg Pro Gly Thr Glu 
945                 950                 955                 960 


Tyr Gly Ile Gly Val Ser Ala Val Lys Glu Asp Lys Glu Ser Asn Pro 
                965                 970                 975     


Ala Thr Ile Asn Ala Ala Thr Glu Leu Asp Thr Pro Lys Asp Leu Gln 
            980                 985                 990         


Val Ser Glu Thr Ala Glu Thr Ser  Leu Thr Leu Leu Trp  Lys Thr Pro 
        995                 1000                 1005             


Leu Ala  Lys Phe Asp Arg Tyr  Arg Leu Asn Tyr Ser  Leu Pro Thr 
    1010                 1015                 1020             


Gly Gln  Trp Val Gly Val Gln  Leu Pro Arg Asn Thr  Thr Ser Tyr 
    1025                 1030                 1035             


Val Leu  Arg Gly Leu Glu Pro  Gly Gln Glu Tyr Asn  Val Leu Leu 
    1040                 1045                 1050             


Thr Ala  Glu Lys Gly Arg His  Lys Ser Lys Pro Ala  Arg Val Lys 
    1055                 1060                 1065             


Ala Ser  Thr Glu Gln Ala Pro  Glu Leu Glu Asn Leu  Thr Val Thr 
    1070                 1075                 1080             


Glu Val  Gly Trp Asp Gly Leu  Arg Leu Asn Trp Thr  Ala Ala Asp 
    1085                 1090                 1095             


Gln Ala  Tyr Glu His Phe Ile  Ile Gln Val Gln Glu  Ala Asn Lys 
    1100                 1105                 1110             


Val Glu  Ala Ala Arg Asn Leu  Thr Val Pro Gly Ser  Leu Arg Ala 
    1115                 1120                 1125             


Val Asp  Ile Pro Gly Leu Lys  Ala Ala Thr Pro Tyr  Thr Val Ser 
    1130                 1135                 1140             


Ile Tyr  Gly Val Ile Gln Gly  Tyr Arg Thr Pro Val  Leu Ser Ala 
    1145                 1150                 1155             


Glu Ala  Ser Thr Gly Glu Thr  Pro Asn Leu Gly Glu  Val Val Val 
    1160                 1165                 1170             


Ala Glu  Val Gly Trp Asp Ala  Leu Lys Leu Asn Trp  Thr Ala Pro 
    1175                 1180                 1185             


Glu Gly  Ala Tyr Glu Tyr Phe  Phe Ile Gln Val Gln  Glu Ala Asp 
    1190                 1195                 1200             


Thr Val  Glu Ala Ala Gln Asn  Leu Thr Val Pro Gly  Gly Leu Arg 
    1205                 1210                 1215             


Ser Thr  Asp Leu Pro Gly Leu  Lys Ala Ala Thr His  Tyr Thr Ile 
    1220                 1225                 1230             


Thr Ile  Arg Gly Val Thr Gln  Asp Phe Ser Thr Thr  Pro Leu Ser 
    1235                 1240                 1245             


Val Glu  Val Leu Thr Glu Glu  Val Pro Asp Met Gly  Asn Leu Thr 
    1250                 1255                 1260             


Val Thr  Glu Val Ser Trp Asp  Ala Leu Arg Leu Asn  Trp Thr Thr 
    1265                 1270                 1275             


Pro Asp  Gly Thr Tyr Asp Gln  Phe Thr Ile Gln Val  Gln Glu Ala 
    1280                 1285                 1290             


Asp Gln  Val Glu Glu Ala His  Asn Leu Thr Val Pro  Gly Ser Leu 
    1295                 1300                 1305             


Arg Ser  Met Glu Ile Pro Gly  Leu Arg Ala Gly Thr  Pro Tyr Thr 
    1310                 1315                 1320             


Val Thr  Leu His Gly Glu Val  Arg Gly His Ser Thr  Arg Pro Leu 
    1325                 1330                 1335             


Ala Val  Glu Val Val Thr Glu  Asp Leu Pro Gln Leu  Gly Asp Leu 
    1340                 1345                 1350             


Ala Val  Ser Glu Val Gly Trp  Asp Gly Leu Arg Leu  Asn Trp Thr 
    1355                 1360                 1365             


Ala Ala  Asp Asn Ala Tyr Glu  His Phe Val Ile Gln  Val Gln Glu 
    1370                 1375                 1380             


Val Asn  Lys Val Glu Ala Ala  Gln Asn Leu Thr Leu  Pro Gly Ser 
    1385                 1390                 1395             


Leu Arg  Ala Val Asp Ile Pro  Gly Leu Glu Ala Ala  Thr Pro Tyr 
    1400                 1405                 1410             


Arg Val  Ser Ile Tyr Gly Val  Ile Arg Gly Tyr Arg  Thr Pro Val 
    1415                 1420                 1425             


Leu Ser  Ala Glu Ala Ser Thr  Ala Lys Glu Pro Glu  Ile Gly Asn 
    1430                 1435                 1440             


Leu Asn  Val Ser Asp Ile Thr  Pro Glu Ser Phe Asn  Leu Ser Trp 
    1445                 1450                 1455             


Met Ala  Thr Asp Gly Ile Phe  Glu Thr Phe Thr Ile  Glu Ile Ile 
    1460                 1465                 1470             


Asp Ser  Asn Arg Leu Leu Glu  Thr Val Glu Tyr Asn  Ile Ser Gly 
    1475                 1480                 1485             


Ala Glu  Arg Thr Ala His Ile  Ser Gly Leu Pro Pro  Ser Thr Asp 
    1490                 1495                 1500             


Phe Ile  Val Tyr Leu Ser Gly  Leu Ala Pro Ser Ile  Arg Thr Lys 
    1505                 1510                 1515             


Thr Ile  Ser Ala Thr Ala Thr  Thr Glu Ala Leu Pro  Leu Leu Glu 
    1520                 1525                 1530             


Asn Leu  Thr Ile Ser Asp Ile  Asn Pro Tyr Gly Phe  Thr Val Ser 
    1535                 1540                 1545             


Trp Met  Ala Ser Glu Asn Ala  Phe Asp Ser Phe Leu  Val Thr Val 
    1550                 1555                 1560             


Val Asp  Ser Gly Lys Leu Leu  Asp Pro Gln Glu Phe  Thr Leu Ser 
    1565                 1570                 1575             


Gly Thr  Gln Arg Lys Leu Glu  Leu Arg Gly Leu Ile  Thr Gly Ile 
    1580                 1585                 1590             


Gly Tyr  Glu Val Met Val Ser  Gly Phe Thr Gln Gly  His Gln Thr 
    1595                 1600                 1605             


Lys Pro  Leu Arg Ala Glu Ile  Val Thr Glu Ala Glu  Pro Glu Val 
    1610                 1615                 1620             


Asp Asn  Leu Leu Val Ser Asp  Ala Thr Pro Asp Gly  Phe Arg Leu 
    1625                 1630                 1635             


Ser Trp  Thr Ala Asp Glu Gly  Val Phe Asp Asn Phe  Val Leu Lys 
    1640                 1645                 1650             


Ile Arg  Asp Thr Lys Lys Gln  Ser Glu Pro Leu Glu  Ile Thr Leu 
    1655                 1660                 1665             


Leu Ala  Pro Glu Arg Thr Arg  Asp Ile Thr Gly Leu  Arg Glu Ala 
    1670                 1675                 1680             


Thr Glu  Tyr Glu Ile Glu Leu  Tyr Gly Ile Ser Lys  Gly Arg Arg 
    1685                 1690                 1695             


Ser Gln  Thr Val Ser Ala Ile  Ala Thr Thr Ala Met  Gly Ser Pro 
    1700                 1705                 1710             


Lys Glu  Val Ile Phe Ser Asp  Ile Thr Glu Asn Ser  Ala Thr Val 
    1715                 1720                 1725             


Ser Trp  Arg Ala Pro Thr Ala  Gln Val Glu Ser Phe  Arg Ile Thr 
    1730                 1735                 1740             


Tyr Val  Pro Ile Thr Gly Gly  Thr Pro Ser Met Val  Thr Val Asp 
    1745                 1750                 1755             


Gly Thr  Lys Thr Gln Thr Arg  Leu Val Lys Leu Ile  Pro Gly Val 
    1760                 1765                 1770             


Glu Tyr  Leu Val Ser Ile Ile  Ala Met Lys Gly Phe  Glu Glu Ser 
    1775                 1780                 1785             


Glu Pro  Val Ser Gly Ser Phe  Thr Thr Ala Leu Asp  Gly Pro Ser 
    1790                 1795                 1800             


Gly Leu  Val Thr Ala Asn Ile  Thr Asp Ser Glu Ala  Leu Ala Arg 
    1805                 1810                 1815             


Trp Gln  Pro Ala Ile Ala Thr  Val Asp Ser Tyr Val  Ile Ser Tyr 
    1820                 1825                 1830             


Thr Gly  Glu Lys Val Pro Glu  Ile Thr Arg Thr Val  Ser Gly Asn 
    1835                 1840                 1845             


Thr Val  Glu Tyr Ala Leu Thr  Asp Leu Glu Pro Ala  Thr Glu Tyr 
    1850                 1855                 1860             


Thr Leu  Arg Ile Phe Ala Glu  Lys Gly Pro Gln Lys  Ser Ser Thr 
    1865                 1870                 1875             


Ile Thr  Ala Lys Phe Thr Thr  Asp Leu Asp Ser Pro  Arg Asp Leu 
    1880                 1885                 1890             


Thr Ala  Thr Glu Val Gln Ser  Glu Thr Ala Leu Leu  Thr Trp Arg 
    1895                 1900                 1905             


Pro Pro  Arg Ala Ser Val Thr  Gly Tyr Leu Leu Val  Tyr Glu Ser 
    1910                 1915                 1920             


Val Asp  Gly Thr Val Lys Glu  Val Ile Val Gly Pro  Asp Thr Thr 
    1925                 1930                 1935             


Ser Tyr  Ser Leu Ala Asp Leu  Ser Pro Ser Thr His  Tyr Thr Ala 
    1940                 1945                 1950             


Lys Ile  Gln Ala Leu Asn Gly  Pro Leu Arg Ser Asn  Met Ile Gln 
    1955                 1960                 1965             


Thr Ile  Phe Thr Thr Ile Gly  Leu Leu Tyr Pro Phe  Pro Lys Asp 
    1970                 1975                 1980             


Cys Ser  Gln Ala Met Leu Asn  Gly Asp Thr Thr Ser  Gly Leu Tyr 
    1985                 1990                 1995             


Thr Ile  Tyr Leu Asn Gly Asp  Lys Ala Glu Ala Leu  Glu Val Phe 
    2000                 2005                 2010             


Cys Asp  Met Thr Ser Asp Gly  Gly Gly Trp Ile Val  Phe Leu Arg 
    2015                 2020                 2025             


Arg Lys  Asn Gly Arg Glu Asn  Phe Tyr Gln Asn Trp  Lys Ala Tyr 
    2030                 2035                 2040             


Ala Ala  Gly Phe Gly Asp Arg  Arg Glu Glu Phe Trp  Leu Gly Leu 
    2045                 2050                 2055             


Asp Asn  Leu Asn Lys Ile Thr  Ala Gln Gly Gln Tyr  Glu Leu Arg 
    2060                 2065                 2070             


Val Asp  Leu Arg Asp His Gly  Glu Thr Ala Phe Ala  Val Tyr Asp 
    2075                 2080                 2085             


Lys Phe  Ser Val Gly Asp Ala  Lys Thr Arg Tyr Lys  Leu Lys Val 
    2090                 2095                 2100             


Glu Gly  Tyr Ser Gly Thr Ala  Gly Asp Ser Met Ala  Tyr His Asn 
    2105                 2110                 2115             


Gly Arg  Ser Phe Ser Thr Phe  Asp Lys Asp Thr Asp  Ser Ala Ile 
    2120                 2125                 2130             


Thr Asn  Cys Ala Leu Ser Tyr  Lys Gly Ala Phe Trp  Tyr Arg Asn 
    2135                 2140                 2145             


Cys His  Arg Val Asn Leu Met  Gly Arg Tyr Gly Asp  Asn Asn His 
    2150                 2155                 2160             


Ser Gln  Gly Val Asn Trp Phe  His Trp Lys Gly His  Glu His Ser 
    2165                 2170                 2175             


Ile Gln  Phe Ala Glu Met Lys  Leu Arg Pro Ser Asn  Phe Arg Asn 
    2180                 2185                 2190             


Leu Glu  Gly Arg Arg Lys Arg  Ala 
    2195                 2200     


<210>  3845
<211>  252
<212>  PRT
<213>  homo sapiens

<400>  3845

Met Ser Gly Arg Arg Thr Arg Ser Gly Gly Ala Ala Gln Arg Ser Gly 
1               5                   10                  15      


Pro Arg Ala Pro Ser Pro Thr Lys Pro Leu Arg Arg Ser Gln Arg Lys 
            20                  25                  30          


Ser Gly Ser Glu Leu Pro Ser Ile Leu Pro Glu Ile Trp Pro Lys Thr 
        35                  40                  45              


Pro Ser Ala Ala Ala Val Arg Lys Pro Ile Val Leu Lys Arg Ile Val 
    50                  55                  60                  


Ala His Ala Val Glu Val Pro Ala Val Gln Ser Pro Arg Arg Ser Pro 
65                  70                  75                  80  


Arg Ile Ser Phe Phe Leu Glu Lys Glu Asn Glu Pro Pro Gly Arg Glu 
                85                  90                  95      


Leu Thr Lys Glu Asp Leu Phe Lys Thr His Ser Val Pro Ala Thr Pro 
            100                 105                 110         


Thr Ser Thr Pro Val Pro Asn Pro Glu Ala Glu Ser Ser Ser Lys Glu 
        115                 120                 125             


Gly Glu Leu Asp Ala Arg Asp Leu Glu Met Ser Lys Lys Val Arg Arg 
    130                 135                 140                 


Ser Tyr Ser Arg Leu Glu Thr Leu Gly Ser Ala Ser Thr Ser Thr Pro 
145                 150                 155                 160 


Gly Arg Arg Ser Cys Phe Gly Phe Glu Gly Leu Leu Gly Ala Glu Asp 
                165                 170                 175     


Leu Ser Gly Val Ser Pro Val Val Cys Ser Lys Leu Thr Glu Val Pro 
            180                 185                 190         


Arg Val Cys Ala Lys Pro Trp Ala Pro Asp Met Thr Leu Pro Gly Ile 
        195                 200                 205             


Ser Pro Pro Pro Glu Lys Gln Lys Arg Lys Lys Lys Lys Met Pro Glu 
    210                 215                 220                 


Ile Leu Lys Thr Glu Leu Asp Glu Trp Ala Ala Ala Met Asn Ala Glu 
225                 230                 235                 240 


Phe Glu Ala Ala Glu Gln Phe Asp Leu Leu Val Glu 
                245                 250         


<210>  3846
<211>  655
<212>  PRT
<213>  homo sapiens

<400>  3846

Met Ala Ser Thr Asp Tyr Ser Thr Tyr Ser Gln Ala Ala Ala Gln Gln 
1               5                   10                  15      


Gly Tyr Ser Ala Tyr Thr Ala Gln Pro Thr Gln Gly Tyr Ala Gln Thr 
            20                  25                  30          


Thr Gln Ala Tyr Gly Gln Gln Ser Tyr Gly Thr Tyr Gly Gln Pro Thr 
        35                  40                  45              


Asp Val Ser Tyr Thr Gln Ala Gln Thr Thr Ala Thr Tyr Gly Gln Thr 
    50                  55                  60                  


Ala Tyr Ala Thr Ser Tyr Gly Gln Pro Pro Thr Gly Tyr Thr Thr Pro 
65                  70                  75                  80  


Thr Ala Pro Gln Ala Tyr Ser Gln Pro Val Gln Gly Tyr Gly Thr Gly 
                85                  90                  95      


Ala Tyr Asp Thr Thr Thr Ala Thr Val Thr Thr Thr Gln Ala Ser Tyr 
            100                 105                 110         


Ala Ala Gln Ser Ala Tyr Gly Thr Gln Pro Ala Tyr Pro Ala Tyr Gly 
        115                 120                 125             


Gln Gln Pro Ala Ala Thr Ala Pro Thr Arg Pro Gln Asp Gly Asn Lys 
    130                 135                 140                 


Pro Thr Glu Thr Ser Gln Pro Gln Ser Ser Thr Gly Gly Tyr Asn Gln 
145                 150                 155                 160 


Pro Ser Leu Gly Tyr Gly Gln Ser Asn Tyr Ser Tyr Pro Gln Val Pro 
                165                 170                 175     


Gly Ser Tyr Pro Met Gln Pro Val Thr Ala Pro Pro Ser Tyr Pro Pro 
            180                 185                 190         


Thr Ser Tyr Ser Ser Thr Gln Pro Thr Ser Tyr Asp Gln Ser Ser Tyr 
        195                 200                 205             


Ser Gln Gln Asn Thr Tyr Gly Gln Pro Ser Ser Tyr Gly Gln Gln Ser 
    210                 215                 220                 


Ser Tyr Gly Gln Gln Ser Ser Tyr Gly Gln Gln Pro Pro Thr Ser Tyr 
225                 230                 235                 240 


Pro Pro Gln Thr Gly Ser Tyr Ser Gln Ala Pro Ser Gln Tyr Ser Gln 
                245                 250                 255     


Gln Ser Ser Ser Tyr Gly Gln Gln Ser Ser Phe Arg Gln Asp His Pro 
            260                 265                 270         


Ser Ser Met Gly Val Tyr Gly Gln Glu Ser Gly Gly Phe Ser Gly Pro 
        275                 280                 285             


Gly Glu Asn Arg Ser Met Ser Gly Pro Asp Asn Arg Gly Arg Gly Arg 
    290                 295                 300                 


Gly Gly Phe Asp Arg Gly Gly Met Ser Arg Gly Gly Arg Gly Gly Gly 
305                 310                 315                 320 


Arg Gly Gly Met Gly Ala Gly Glu Arg Gly Gly Phe Asn Lys Pro Gly 
                325                 330                 335     


Gly Pro Met Asp Glu Gly Pro Asp Leu Asp Leu Gly Pro Pro Val Asp 
            340                 345                 350         


Pro Asp Glu Asp Ser Asp Asn Ser Ala Ile Tyr Val Gln Gly Leu Asn 
        355                 360                 365             


Asp Ser Val Thr Leu Asp Asp Leu Ala Asp Phe Phe Lys Gln Cys Gly 
    370                 375                 380                 


Val Val Lys Met Asn Lys Arg Thr Gly Gln Pro Met Ile His Ile Tyr 
385                 390                 395                 400 


Leu Asp Lys Glu Thr Gly Lys Pro Lys Gly Asp Ala Thr Val Ser Tyr 
                405                 410                 415     


Glu Asp Pro Pro Thr Ala Lys Ala Ala Val Glu Trp Phe Asp Gly Lys 
            420                 425                 430         


Asp Phe Gln Gly Ser Lys Leu Lys Val Ser Leu Ala Arg Lys Lys Pro 
        435                 440                 445             


Pro Met Asn Ser Met Arg Gly Gly Leu Pro Pro Arg Glu Gly Arg Gly 
    450                 455                 460                 


Met Pro Pro Pro Leu Arg Gly Gly Pro Gly Gly Pro Gly Gly Pro Gly 
465                 470                 475                 480 


Gly Pro Met Gly Arg Met Gly Gly Arg Gly Gly Asp Arg Gly Gly Phe 
                485                 490                 495     


Pro Pro Arg Gly Pro Arg Gly Ser Arg Gly Asn Pro Ser Gly Gly Gly 
            500                 505                 510         


Asn Val Gln His Arg Ala Gly Asp Trp Gln Cys Pro Asn Pro Gly Cys 
        515                 520                 525             


Gly Asn Gln Asn Phe Ala Trp Arg Thr Glu Cys Asn Gln Cys Lys Ala 
    530                 535                 540                 


Pro Lys Pro Glu Gly Phe Leu Pro Pro Pro Phe Pro Pro Pro Gly Gly 
545                 550                 555                 560 


Asp Arg Gly Arg Gly Gly Pro Gly Gly Met Arg Gly Gly Arg Gly Gly 
                565                 570                 575     


Leu Met Asp Arg Gly Gly Pro Gly Gly Met Phe Arg Gly Gly Arg Gly 
            580                 585                 590         


Gly Asp Arg Gly Gly Phe Arg Gly Gly Arg Gly Met Asp Arg Gly Gly 
        595                 600                 605             


Phe Gly Gly Gly Arg Arg Gly Gly Pro Gly Gly Pro Pro Gly Pro Leu 
    610                 615                 620                 


Met Glu Gln Met Gly Gly Arg Arg Gly Gly Arg Gly Gly Pro Gly Lys 
625                 630                 635                 640 


Met Asp Lys Gly Glu His Arg Gln Glu Arg Arg Asp Arg Pro Tyr 
                645                 650                 655 


<210>  3847
<211>  600
<212>  PRT
<213>  homo sapiens

<400>  3847

Met Ala Ser Thr Asp Tyr Ser Thr Tyr Ser Gln Ala Ala Ala Gln Gln 
1               5                   10                  15      


Gly Tyr Ser Ala Tyr Thr Ala Gln Pro Thr Gln Gly Tyr Ala Gln Thr 
            20                  25                  30          


Thr Gln Ala Tyr Gly Gln Gln Ser Tyr Gly Thr Tyr Gly Gln Pro Thr 
        35                  40                  45              


Asp Val Ser Tyr Thr Gln Ala Gln Thr Thr Ala Thr Tyr Gly Gln Thr 
    50                  55                  60                  


Ala Tyr Ala Thr Ser Tyr Gly Gln Pro Pro Thr Gly Tyr Thr Thr Pro 
65                  70                  75                  80  


Thr Ala Pro Gln Ala Tyr Ser Gln Pro Val Gln Gly Tyr Gly Thr Gly 
                85                  90                  95      


Ala Tyr Asp Thr Thr Thr Ala Thr Val Thr Thr Thr Gln Ala Ser Tyr 
            100                 105                 110         


Ala Ala Gln Ser Ala Tyr Gly Thr Gln Pro Ala Tyr Pro Ala Tyr Gly 
        115                 120                 125             


Gln Gln Pro Ala Ala Thr Ala Pro Thr Ser Tyr Ser Ser Thr Gln Pro 
    130                 135                 140                 


Thr Ser Tyr Asp Gln Ser Ser Tyr Ser Gln Gln Asn Thr Tyr Gly Gln 
145                 150                 155                 160 


Pro Ser Ser Tyr Gly Gln Gln Ser Ser Tyr Gly Gln Gln Ser Ser Tyr 
                165                 170                 175     


Gly Gln Gln Pro Pro Thr Ser Tyr Pro Pro Gln Thr Gly Ser Tyr Ser 
            180                 185                 190         


Gln Ala Pro Ser Gln Tyr Ser Gln Gln Ser Ser Ser Tyr Gly Gln Gln 
        195                 200                 205             


Ser Ser Phe Arg Gln Asp His Pro Ser Ser Met Gly Val Tyr Gly Gln 
    210                 215                 220                 


Glu Ser Gly Gly Phe Ser Gly Pro Gly Glu Asn Arg Ser Met Ser Gly 
225                 230                 235                 240 


Pro Asp Asn Arg Gly Arg Gly Arg Gly Gly Phe Asp Arg Gly Gly Met 
                245                 250                 255     


Ser Arg Gly Gly Arg Gly Gly Gly Arg Gly Gly Met Gly Ser Ala Gly 
            260                 265                 270         


Glu Arg Gly Gly Phe Asn Lys Pro Gly Gly Pro Met Asp Glu Gly Pro 
        275                 280                 285             


Asp Leu Asp Leu Gly Pro Pro Val Asp Pro Asp Glu Asp Ser Asp Asn 
    290                 295                 300                 


Ser Ala Ile Tyr Val Gln Gly Leu Asn Asp Ser Val Thr Leu Asp Asp 
305                 310                 315                 320 


Leu Ala Asp Phe Phe Lys Gln Cys Gly Val Val Lys Met Asn Lys Arg 
                325                 330                 335     


Thr Gly Gln Pro Met Ile His Ile Tyr Leu Asp Lys Glu Thr Gly Lys 
            340                 345                 350         


Pro Lys Gly Asp Ala Thr Val Ser Tyr Glu Asp Pro Pro Thr Ala Lys 
        355                 360                 365             


Ala Ala Val Glu Trp Phe Asp Gly Lys Asp Phe Gln Gly Ser Lys Leu 
    370                 375                 380                 


Lys Val Ser Leu Ala Arg Lys Lys Pro Pro Met Asn Ser Met Arg Gly 
385                 390                 395                 400 


Gly Leu Pro Pro Arg Glu Gly Arg Gly Met Pro Pro Pro Leu Arg Gly 
                405                 410                 415     


Gly Pro Gly Gly Pro Gly Gly Pro Gly Gly Pro Met Gly Arg Met Gly 
            420                 425                 430         


Gly Arg Gly Gly Asp Arg Gly Gly Phe Pro Pro Arg Gly Pro Arg Gly 
        435                 440                 445             


Ser Arg Gly Asn Pro Ser Gly Gly Gly Asn Val Gln His Arg Ala Gly 
    450                 455                 460                 


Asp Trp Gln Cys Pro Asn Pro Gly Cys Gly Asn Gln Asn Phe Ala Trp 
465                 470                 475                 480 


Arg Thr Glu Cys Asn Gln Cys Lys Ala Pro Lys Pro Glu Gly Phe Leu 
                485                 490                 495     


Pro Pro Pro Phe Pro Pro Pro Gly Gly Asp Arg Gly Arg Gly Gly Pro 
            500                 505                 510         


Gly Gly Met Arg Gly Gly Arg Gly Gly Leu Met Asp Arg Gly Gly Pro 
        515                 520                 525             


Gly Gly Met Phe Arg Gly Gly Arg Gly Gly Asp Arg Gly Gly Phe Arg 
    530                 535                 540                 


Gly Gly Arg Gly Met Asp Arg Gly Gly Phe Gly Gly Gly Arg Arg Gly 
545                 550                 555                 560 


Gly Pro Gly Gly Pro Pro Gly Pro Leu Met Glu Gln Met Gly Gly Arg 
                565                 570                 575     


Arg Gly Gly Arg Gly Gly Pro Gly Lys Met Asp Lys Gly Glu His Arg 
            580                 585                 590         


Gln Glu Arg Arg Asp Arg Pro Tyr 
        595                 600 


<210>  3848
<211>  354
<212>  PRT
<213>  homo sapiens

<400>  3848

Met Ala Ser Thr Asp Tyr Ser Thr Tyr Ser Gln Ala Ala Ala Gln Gln 
1               5                   10                  15      


Gly Tyr Ser Ala Tyr Thr Ala Gln Pro Thr Gln Gly Tyr Ala Gln Thr 
            20                  25                  30          


Thr Gln Ala Tyr Gly Gln Gln Ser Tyr Gly Thr Tyr Gly Gln Pro Thr 
        35                  40                  45              


Asp Val Ser Tyr Thr Gln Ala Gln Thr Thr Ala Thr Tyr Gly Gln Thr 
    50                  55                  60                  


Ala Tyr Ala Thr Ser Tyr Gly Gln Pro Pro Thr Gly Tyr Thr Thr Pro 
65                  70                  75                  80  


Thr Ala Pro Gln Ala Tyr Ser Gln Pro Val Gln Gly Tyr Gly Thr Gly 
                85                  90                  95      


Ala Tyr Asp Thr Thr Thr Ala Thr Val Thr Thr Thr Gln Ala Ser Tyr 
            100                 105                 110         


Ala Ala Gln Ser Ala Tyr Gly Thr Gln Pro Ala Tyr Pro Ala Tyr Gly 
        115                 120                 125             


Gln Gln Pro Ala Ala Thr Ala Pro Thr Arg Pro Gln Asp Gly Asn Lys 
    130                 135                 140                 


Pro Thr Glu Thr Ser Gln Pro Gln Ser Ser Thr Gly Gly Tyr Asn Gln 
145                 150                 155                 160 


Pro Ser Leu Gly Tyr Gly Gln Ser Asn Tyr Ser Tyr Pro Gln Val Pro 
                165                 170                 175     


Gly Ser Tyr Pro Met Gln Pro Val Thr Ala Pro Pro Ser Tyr Pro Pro 
            180                 185                 190         


Thr Ser Tyr Ser Ser Thr Gln Pro Thr Ser Tyr Asp Gln Ser Ser Tyr 
        195                 200                 205             


Ser Gln Gln Asn Thr Tyr Gly Gln Pro Ser Ser Tyr Gly Gln Gln Ser 
    210                 215                 220                 


Ser Tyr Gly Gln Gln Ser Ser Tyr Gly Gln Gln Pro Pro Thr Ser Tyr 
225                 230                 235                 240 


Pro Pro Gln Thr Gly Ser Tyr Ser Gln Ala Pro Ser Gln Tyr Ser Gln 
                245                 250                 255     


Gln Ser Ser Ser Tyr Gly Gln Gln Ser Ser Phe Arg Gln Asp His Pro 
            260                 265                 270         


Ser Ser Met Gly Val Tyr Gly Gln Glu Ser Gly Gly Phe Ser Gly Pro 
        275                 280                 285             


Gly Glu Asn Arg Ser Met Ser Gly Pro Asp Asn Arg Gly Arg Gly Arg 
    290                 295                 300                 


Gly Gly Phe Asp Arg Gly Gly Met Ser Arg Gly Gly Arg Gly Gly Gly 
305                 310                 315                 320 


Arg Gly Gly Met Gly Leu Gln Ser Glu Ser Leu Val Tyr Thr Ser Ile 
                325                 330                 335     


Leu Lys Lys Tyr Pro Tyr Ser Val Leu Ser Arg Gln His Asn Glu Lys 
            340                 345                 350         


Trp Asp 
        


<210>  3849
<211>  666
<212>  PRT
<213>  homo sapiens

<400>  3849

Met Asn Thr Gly Arg Asp Ser Gln Ser Pro Asp Ser Ala Lys Gly Phe 
1               5                   10                  15      


Arg Ser Val Arg Pro Asn Leu Gln Asp Lys Arg Ser Pro Thr Gln Ser 
            20                  25                  30          


Gln Ile Thr Val Asn Gly Asn Ser Gly Gly Ala Val Ser Pro Met Ser 
        35                  40                  45              


Tyr Tyr Gln Arg Pro Phe Ser Pro Ser Ala Tyr Ser Leu Pro Ala Ser 
    50                  55                  60                  


Leu Asn Ser Ser Ile Val Met Gln His Gly Thr Ser Leu Asp Ser Thr 
65                  70                  75                  80  


Asp Thr Tyr Pro Gln His Ala Gln Ser Leu Asp Gly Thr Thr Ser Ser 
                85                  90                  95      


Ser Ile Pro Leu Tyr Arg Ser Ser Glu Glu Glu Lys Arg Val Thr Val 
            100                 105                 110         


Ile Lys Ala Pro His Tyr Pro Gly Ile Gly Pro Val Asp Glu Ser Gly 
        115                 120                 125             


Ile Pro Thr Ala Ile Arg Thr Thr Val Asp Arg Pro Lys Asp Trp Tyr 
    130                 135                 140                 


Lys Thr Met Phe Lys Gln Ile His Met Val His Lys Pro Asp Asp Asp 
145                 150                 155                 160 


Thr Asp Met Tyr Asn Thr Pro Tyr Thr Tyr Asn Ala Gly Leu Tyr Asn 
                165                 170                 175     


Pro Pro Tyr Ser Ala Gln Ser His Pro Ala Ala Lys Thr Gln Thr Tyr 
            180                 185                 190         


Arg Pro Leu Ser Lys Ser His Ser Asp Asn Ser Pro Asn Ala Phe Lys 
        195                 200                 205             


Asp Ala Ser Ser Pro Val Pro Pro Pro His Val Pro Pro Pro Val Pro 
    210                 215                 220                 


Pro Leu Arg Pro Arg Asp Arg Ser Ser Thr Glu Lys His Asp Trp Asp 
225                 230                 235                 240 


Pro Pro Asp Arg Lys Val Asp Thr Arg Lys Phe Arg Ser Glu Pro Arg 
                245                 250                 255     


Ser Ile Phe Glu Tyr Glu Pro Gly Lys Ser Ser Ile Leu Gln His Glu 
            260                 265                 270         


Arg Pro Thr Asp Arg Ile Asn Pro Asp Asp Ile Asp Leu Glu Asn Glu 
        275                 280                 285             


Pro Trp Tyr Lys Phe Phe Ser Glu Leu Glu Phe Gly Arg Pro Pro Pro 
    290                 295                 300                 


Lys Lys Pro Leu Asp Tyr Val Gln Asp His Ser Ser Gly Val Phe Asn 
305                 310                 315                 320 


Glu Ala Ser Leu Tyr Gln Ser Ser Ile Asp Arg Ser Leu Glu Arg Pro 
                325                 330                 335     


Met Ser Ser Ala Ser Met Ala Ser Asp Phe Arg Lys Arg Arg Lys Ser 
            340                 345                 350         


Glu Pro Ala Val Gly Pro Pro Arg Gly Leu Gly Asp Gln Ser Ala Ser 
        355                 360                 365             


Arg Thr Ser Pro Gly Arg Val Asp Leu Pro Gly Ser Ser Thr Thr Leu 
    370                 375                 380                 


Thr Lys Ser Phe Thr Ser Ser Ser Pro Ser Ser Pro Ser Arg Ala Lys 
385                 390                 395                 400 


Asp Arg Glu Ser Pro Arg Ser Tyr Ser Ser Thr Leu Thr Asp Met Gly 
                405                 410                 415     


Arg Ser Ala Pro Arg Glu Arg Arg Gly Thr Pro Glu Lys Glu Lys Leu 
            420                 425                 430         


Pro Ala Lys Ala Val Tyr Asp Phe Lys Ala Gln Thr Ser Lys Glu Leu 
        435                 440                 445             


Ser Phe Lys Lys Gly Asp Thr Val Tyr Ile Leu Arg Lys Ile Asp Gln 
    450                 455                 460                 


Asn Trp Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe Pro Ile 
465                 470                 475                 480 


Ser Tyr Val Glu Lys Leu Thr Pro Pro Glu Lys Ala Gln Pro Ala Arg 
                485                 490                 495     


Pro Pro Pro Pro Ala Gln Pro Gly Glu Ile Gly Glu Ala Ile Ala Lys 
            500                 505                 510         


Tyr Asn Phe Asn Ala Asp Thr Asn Val Glu Leu Ser Leu Arg Lys Gly 
        515                 520                 525             


Asp Arg Val Ile Leu Leu Lys Arg Val Asp Gln Asn Trp Tyr Glu Gly 
    530                 535                 540                 


Lys Ile Pro Gly Thr Asn Arg Gln Gly Ile Phe Pro Val Ser Tyr Val 
545                 550                 555                 560 


Glu Val Val Lys Lys Asn Thr Lys Gly Ala Glu Asp Tyr Pro Asp Pro 
                565                 570                 575     


Pro Ile Pro His Ser Tyr Ser Ser Asp Arg Ile His Ser Leu Ser Ser 
            580                 585                 590         


Asn Lys Pro Gln Arg Pro Val Phe Thr His Glu Asn Ile Gln Gly Gly 
        595                 600                 605             


Gly Glu Pro Phe Gln Ala Leu Tyr Asn Tyr Thr Pro Arg Asn Glu Asp 
    610                 615                 620                 


Glu Leu Glu Leu Arg Glu Ser Asp Val Ile Asp Val Met Glu Lys Cys 
625                 630                 635                 640 


Asp Asp Gly Trp Phe Val Gly Thr Ser Arg Arg Thr Lys Phe Phe Gly 
                645                 650                 655     


Thr Phe Pro Gly Asn Tyr Val Lys Arg Leu 
            660                 665     


<210>  3850
<211>  644
<212>  PRT
<213>  homo sapiens

<400>  3850

Met Ser Val Thr Leu Thr Ser Val Lys Arg Val Gln Ser Ser Pro Asn 
1               5                   10                  15      


Leu Leu Ala Ala Gly Arg Asp Ser Gln Ser Pro Asp Ser Ala Trp Arg 
            20                  25                  30          


Ser Tyr Asn Asp Gly Asn Gln Glu Thr Leu Asn Gly Asp Ala Thr Tyr 
        35                  40                  45              


Ser Ser Leu Ala Ala Lys Gly Phe Arg Ser Val Arg Pro Asn Leu Gln 
    50                  55                  60                  


Asp Lys Arg Ser Pro Thr Gln Ser Gln Ile Thr Val Asn Gly Asn Ser 
65                  70                  75                  80  


Gly Gly Ala Val Ser Pro Met Ser Tyr Tyr Gln Arg Pro Phe Ser Pro 
                85                  90                  95      


Ser Ala Tyr Ser Leu Pro Ala Ser Leu Asn Ser Ser Ile Val Met Gln 
            100                 105                 110         


His Gly Thr Ser Leu Asp Ser Thr Asp Thr Tyr Pro Gln His Ala Gln 
        115                 120                 125             


Ser Leu Asp Gly Thr Thr Ser Ser Ser Ile Pro Leu Tyr Arg Ser Ser 
    130                 135                 140                 


Glu Glu Glu Lys Arg Val Thr Val Ile Lys Ala Pro His Tyr Pro Gly 
145                 150                 155                 160 


Ile Gly Pro Val Asp Glu Ser Gly Ile Pro Thr Ala Ile Arg Thr Thr 
                165                 170                 175     


Val Asp Arg Pro Lys Asp Trp Tyr Lys Thr Met Phe Lys Gln Ile His 
            180                 185                 190         


Met Val His Lys Pro Gly Leu Tyr Asn Pro Pro Tyr Ser Ala Gln Ser 
        195                 200                 205             


His Pro Ala Ala Lys Thr Gln Thr Tyr Arg Pro Leu Ser Lys Ser His 
    210                 215                 220                 


Ser Asp Asn Ser Pro Asn Ala Phe Lys Asp Ala Ser Ser Pro Val Pro 
225                 230                 235                 240 


Pro Pro His Val Pro Pro Pro Val Pro Pro Leu Arg Pro Arg Asp Arg 
                245                 250                 255     


Ser Ser Thr Glu Lys His Asp Trp Asp Pro Pro Asp Arg Lys Val Asp 
            260                 265                 270         


Thr Arg Lys Phe Arg Ser Glu Pro Arg Ser Ile Phe Glu Tyr Glu Pro 
        275                 280                 285             


Gly Lys Ser Ser Ile Leu Gln His Glu Arg Pro Ala Ser Leu Tyr Gln 
    290                 295                 300                 


Ser Ser Ile Asp Arg Ser Leu Glu Arg Pro Met Ser Ser Ala Ser Met 
305                 310                 315                 320 


Ala Ser Asp Phe Arg Lys Arg Arg Lys Ser Glu Pro Ala Val Gly Pro 
                325                 330                 335     


Pro Arg Gly Leu Gly Asp Gln Ser Ala Ser Arg Thr Ser Pro Gly Arg 
            340                 345                 350         


Val Asp Leu Pro Gly Ser Ser Thr Thr Leu Thr Lys Ser Phe Thr Ser 
        355                 360                 365             


Ser Ser Pro Ser Ser Pro Ser Arg Ala Lys Asp Arg Glu Ser Pro Arg 
    370                 375                 380                 


Ser Tyr Ser Ser Thr Leu Thr Asp Met Gly Arg Ser Ala Pro Arg Glu 
385                 390                 395                 400 


Arg Arg Gly Thr Pro Glu Lys Glu Lys Leu Pro Ala Lys Ala Val Tyr 
                405                 410                 415     


Asp Phe Lys Ala Gln Thr Ser Lys Glu Leu Ser Phe Lys Lys Gly Asp 
            420                 425                 430         


Thr Val Tyr Ile Leu Arg Lys Ile Asp Gln Asn Trp Tyr Glu Gly Glu 
        435                 440                 445             


His His Gly Arg Val Gly Ile Phe Pro Ile Ser Tyr Val Glu Lys Leu 
    450                 455                 460                 


Thr Pro Pro Glu Lys Ala Gln Pro Ala Arg Pro Pro Pro Pro Ala Gln 
465                 470                 475                 480 


Pro Gly Glu Ile Gly Glu Ala Ile Ala Lys Tyr Asn Phe Asn Ala Asp 
                485                 490                 495     


Thr Asn Val Glu Leu Ser Leu Arg Lys Gly Asp Arg Val Ile Leu Leu 
            500                 505                 510         


Lys Arg Val Asp Gln Asn Trp Tyr Glu Gly Lys Ile Pro Gly Thr Asn 
        515                 520                 525             


Arg Gln Gly Ile Phe Pro Val Ser Tyr Val Glu Val Val Lys Lys Asn 
    530                 535                 540                 


Thr Lys Gly Ala Glu Asp Tyr Pro Asp Pro Pro Ile Pro His Ser Tyr 
545                 550                 555                 560 


Ser Ser Asp Arg Ile His Ser Leu Ser Ser Asn Lys Pro Gln Arg Pro 
                565                 570                 575     


Val Phe Thr His Glu Asn Ile Gln Gly Gly Gly Glu Pro Phe Gln Ala 
            580                 585                 590         


Leu Tyr Asn Tyr Thr Pro Arg Asn Glu Asp Glu Leu Glu Leu Arg Glu 
        595                 600                 605             


Ser Asp Val Ile Asp Val Met Glu Lys Cys Asp Asp Gly Trp Phe Val 
    610                 615                 620                 


Gly Thr Ser Arg Arg Thr Lys Phe Phe Gly Thr Phe Pro Gly Asn Tyr 
625                 630                 635                 640 


Val Lys Arg Leu 
                


<210>  3851
<211>  731
<212>  PRT
<213>  homo sapiens

<400>  3851

Met Ser Val Thr Leu Thr Ser Val Lys Arg Val Gln Ser Ser Pro Asn 
1               5                   10                  15      


Leu Leu Ala Ala Gly Arg Asp Ser Gln Ser Pro Asp Ser Ala Trp Arg 
            20                  25                  30          


Ser Tyr Asn Asp Gly Asn Gln Glu Thr Leu Asn Gly Asp Ala Thr Tyr 
        35                  40                  45              


Ser Ser Leu Ala Ala Lys Gly Phe Arg Ser Val Arg Pro Asn Leu Gln 
    50                  55                  60                  


Asp Lys Arg Ser Pro Thr Gln Ser Gln Ile Thr Val Asn Gly Asn Ser 
65                  70                  75                  80  


Gly Gly Ala Val Ser Pro Met Ser Tyr Tyr Gln Arg Pro Phe Ser Pro 
                85                  90                  95      


Ser Ala Tyr Ser Leu Pro Ala Ser Leu Asn Ser Ser Ile Val Met Gln 
            100                 105                 110         


His Gly Thr Ser Leu Asp Ser Thr Asp Thr Tyr Pro Gln His Ala Gln 
        115                 120                 125             


Ser Leu Asp Gly Thr Thr Ser Ser Ser Ile Pro Leu Tyr Arg Ser Ser 
    130                 135                 140                 


Glu Glu Glu Lys Arg Val Thr Val Ile Lys Ala Pro His Tyr Pro Gly 
145                 150                 155                 160 


Ile Gly Pro Val Asp Glu Ser Gly Ile Pro Thr Ala Ile Arg Thr Thr 
                165                 170                 175     


Val Asp Arg Pro Lys Asp Trp Tyr Lys Thr Met Phe Lys Gln Ile His 
            180                 185                 190         


Met Val His Lys Pro Asp Asp Asp Thr Asp Met Tyr Asn Thr Pro Tyr 
        195                 200                 205             


Thr Tyr Asn Ala Gly Leu Tyr Asn Pro Pro Tyr Ser Ala Gln Ser His 
    210                 215                 220                 


Pro Ala Ala Lys Thr Gln Thr Tyr Arg Pro Leu Ser Lys Ser His Ser 
225                 230                 235                 240 


Asp Asn Ser Pro Asn Ala Phe Lys Asp Ala Ser Ser Pro Val Pro Pro 
                245                 250                 255     


Pro His Val Pro Pro Pro Val Pro Pro Leu Arg Pro Arg Asp Arg Ser 
            260                 265                 270         


Ser Thr Glu Lys His Asp Trp Asp Pro Pro Asp Arg Lys Val Asp Thr 
        275                 280                 285             


Arg Lys Phe Arg Ser Glu Pro Arg Ser Ile Phe Glu Tyr Glu Pro Gly 
    290                 295                 300                 


Lys Ser Ser Ile Leu Gln His Glu Arg Pro Pro Pro Leu Pro Thr Thr 
305                 310                 315                 320 


Pro Thr Pro Val Pro Arg Glu Pro Gly Arg Lys Pro Leu Ser Ser Ser 
                325                 330                 335     


Arg Leu Gly Glu Val Thr Gly Ser Pro Ser Pro Pro Pro Arg Ser Gly 
            340                 345                 350         


Ala Pro Thr Pro Ser Ser Arg Ala Pro Ala Leu Ser Pro Thr Arg Pro 
        355                 360                 365             


Pro Lys Lys Pro Leu Asp Tyr Val Gln Asp His Ser Ser Gly Val Phe 
    370                 375                 380                 


Asn Glu Ala Ser Leu Tyr Gln Ser Ser Ile Asp Arg Ser Leu Glu Arg 
385                 390                 395                 400 


Pro Met Ser Ser Ala Ser Met Ala Ser Asp Phe Arg Lys Arg Arg Lys 
                405                 410                 415     


Ser Glu Pro Ala Val Gly Pro Pro Arg Gly Leu Gly Asp Gln Ser Ala 
            420                 425                 430         


Ser Arg Thr Ser Pro Gly Arg Val Asp Leu Pro Gly Ser Ser Thr Thr 
        435                 440                 445             


Leu Thr Lys Ser Phe Thr Ser Ser Ser Pro Ser Ser Pro Ser Arg Ala 
    450                 455                 460                 


Lys Asp Arg Glu Ser Pro Arg Ser Tyr Ser Ser Thr Leu Thr Asp Met 
465                 470                 475                 480 


Gly Arg Ser Ala Pro Arg Glu Arg Arg Gly Thr Pro Glu Lys Glu Lys 
                485                 490                 495     


Leu Pro Ala Lys Ala Val Tyr Asp Phe Lys Ala Gln Thr Ser Lys Glu 
            500                 505                 510         


Leu Ser Phe Lys Lys Gly Asp Thr Val Tyr Ile Leu Arg Lys Ile Asp 
        515                 520                 525             


Gln Asn Trp Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe Pro 
    530                 535                 540                 


Ile Ser Tyr Val Glu Lys Leu Thr Pro Pro Glu Lys Ala Gln Pro Ala 
545                 550                 555                 560 


Arg Pro Pro Pro Pro Ala Gln Pro Gly Glu Ile Gly Glu Ala Ile Ala 
                565                 570                 575     


Lys Tyr Asn Phe Asn Ala Asp Thr Asn Val Glu Leu Ser Leu Arg Lys 
            580                 585                 590         


Gly Asp Arg Val Ile Leu Leu Lys Arg Val Asp Gln Asn Trp Tyr Glu 
        595                 600                 605             


Gly Lys Ile Pro Gly Thr Asn Arg Gln Gly Ile Phe Pro Val Ser Tyr 
    610                 615                 620                 


Val Glu Val Val Lys Lys Asn Thr Lys Gly Ala Glu Asp Tyr Pro Asp 
625                 630                 635                 640 


Pro Pro Ile Pro His Ser Tyr Ser Ser Asp Arg Ile His Ser Leu Ser 
                645                 650                 655     


Ser Asn Lys Pro Gln Arg Pro Val Phe Thr His Glu Asn Ile Gln Gly 
            660                 665                 670         


Gly Gly Glu Pro Phe Gln Ala Leu Tyr Asn Tyr Thr Pro Arg Asn Glu 
        675                 680                 685             


Asp Glu Leu Glu Leu Arg Glu Ser Asp Val Ile Asp Val Met Glu Lys 
    690                 695                 700                 


Cys Asp Asp Gly Trp Phe Val Gly Thr Ser Arg Arg Thr Lys Phe Phe 
705                 710                 715                 720 


Gly Thr Phe Pro Gly Asn Tyr Val Lys Arg Leu 
                725                 730     


<210>  3852
<211>  630
<212>  PRT
<213>  homo sapiens

<400>  3852

Met Asp Ile Lys Gly Gln Phe Trp Asn Asp Asp Asp Ser Glu Gly Asp 
1               5                   10                  15      


Asn Glu Ser Glu Glu Phe Leu Tyr Gly Val Gln Gly Ser Cys Ala Ala 
            20                  25                  30          


Asp Leu Tyr Arg His Pro Gln Leu Asp Ala Asp Ile Glu Ala Val Lys 
        35                  40                  45              


Glu Ile Tyr Ser Glu Asn Ser Val Ser Ile Arg Glu Tyr Gly Thr Ile 
    50                  55                  60                  


Asp Asp Val Asp Ile Asp Leu His Ile Asn Ile Ser Phe Leu Asp Glu 
65                  70                  75                  80  


Glu Val Ser Thr Ala Trp Lys Val Leu Arg Thr Glu Pro Ile Val Leu 
                85                  90                  95      


Arg Leu Arg Phe Ser Leu Ser Gln Tyr Leu Asp Gly Pro Glu Pro Ser 
            100                 105                 110         


Ile Glu Val Phe Gln Pro Ser Asn Lys Glu Gly Phe Gly Leu Gly Leu 
        115                 120                 125             


Gln Leu Lys Lys Ile Leu Gly Met Phe Thr Ser Gln Gln Trp Lys His 
    130                 135                 140                 


Leu Ser Asn Asp Phe Leu Lys Thr Gln Gln Glu Lys Arg His Ser Trp 
145                 150                 155                 160 


Phe Lys Ala Ser Gly Thr Ile Lys Lys Phe Arg Ala Gly Leu Ser Ile 
                165                 170                 175     


Phe Ser Pro Ile Pro Lys Ser Pro Ser Phe Pro Ile Ile Gln Asp Ser 
            180                 185                 190         


Met Leu Lys Gly Lys Leu Gly Val Pro Glu Leu Arg Val Gly Arg Leu 
        195                 200                 205             


Met Asn Arg Ser Ile Ser Cys Thr Met Lys Asn Pro Lys Val Glu Val 
    210                 215                 220                 


Phe Gly Tyr Pro Pro Ser Pro Gln Ala Gly Leu Leu Cys Pro Gln His 
225                 230                 235                 240 


Val Gly Leu Pro Pro Pro Ala Arg Thr Ser Pro Leu Val Ser Gly His 
                245                 250                 255     


Cys Lys Asn Ile Pro Thr Leu Glu Tyr Gly Phe Leu Val Gln Ile Met 
            260                 265                 270         


Lys Tyr Ala Glu Gln Arg Ile Pro Thr Leu Asn Glu Tyr Cys Val Val 
        275                 280                 285             


Cys Asp Glu Gln His Val Phe Gln Asn Gly Ser Met Leu Lys Pro Ala 
    290                 295                 300                 


Val Cys Thr Arg Glu Leu Cys Val Phe Ser Phe Tyr Thr Leu Gly Val 
305                 310                 315                 320 


Met Ser Gly Ala Ala Glu Glu Val Ala Thr Gly Ala Glu Val Val Asp 
                325                 330                 335     


Leu Leu Val Ala Met Cys Arg Ala Ala Leu Glu Ser Pro Arg Lys Ser 
            340                 345                 350         


Ile Ile Phe Glu Pro Tyr Pro Ser Val Val Asp Pro Thr Asp Pro Lys 
        355                 360                 365             


Thr Leu Ala Phe Asn Pro Lys Lys Lys Asn Tyr Glu Arg Leu Gln Lys 
    370                 375                 380                 


Ala Leu Asp Ser Val Met Ser Ile Arg Glu Met Thr Gln Gly Ser Tyr 
385                 390                 395                 400 


Leu Glu Ile Lys Lys Gln Met Asp Lys Leu Asp Pro Leu Ala His Pro 
                405                 410                 415     


Leu Leu Gln Trp Ile Ile Ser Ser Asn Arg Ser His Ile Val Lys Leu 
            420                 425                 430         


Pro Leu Ser Arg Leu Lys Phe Met His Thr Ser His Gln Phe Leu Leu 
        435                 440                 445             


Leu Ser Ser Pro Pro Ala Lys Glu Ala Arg Phe Arg Thr Ala Lys Lys 
    450                 455                 460                 


Leu Tyr Gly Ser Thr Phe Ala Phe His Gly Ser His Ile Glu Asn Trp 
465                 470                 475                 480 


His Ser Ile Leu Arg Asn Gly Leu Val Asn Ala Ser Tyr Thr Lys Leu 
                485                 490                 495     


Gln Leu His Gly Ala Ala Tyr Gly Lys Gly Ile Tyr Leu Ser Pro Ile 
            500                 505                 510         


Ser Ser Ile Ser Phe Gly Tyr Ser Gly Met Gly Lys Gly Gln His Arg 
        515                 520                 525             


Met Pro Ser Lys Asp Glu Leu Val Gln Arg Tyr Asn Arg Met Asn Thr 
    530                 535                 540                 


Ile Pro Gln Thr Arg Ser Ile Gln Ser Arg Phe Leu Gln Ser Arg Asn 
545                 550                 555                 560 


Leu Asn Cys Ile Ala Leu Cys Glu Val Ile Thr Ser Lys Asp Leu Gln 
                565                 570                 575     


Lys His Gly Asn Ile Trp Val Cys Pro Val Ser Asp His Val Cys Thr 
            580                 585                 590         


Arg Phe Phe Phe Val Tyr Glu Asp Gly Gln Val Gly Asp Ala Asn Ile 
        595                 600                 605             


Asn Thr Gln Asp Pro Lys Ile Gln Lys Glu Ile Met Arg Val Ile Gly 
    610                 615                 620                 


Thr Gln Val Tyr Thr Asn 
625                 630 


<210>  3853
<211>  304
<212>  PRT
<213>  homo sapiens

<400>  3853

Met Ser Ser Ile Lys His Leu Val Tyr Ala Val Ile Arg Phe Leu Arg 
1               5                   10                  15      


Glu Gln Ser Gln Met Asp Thr Tyr Thr Ser Asp Glu Gln Glu Ser Leu 
            20                  25                  30          


Glu Val Ala Ile Gln Cys Leu Glu Thr Val Phe Lys Ile Ser Pro Glu 
        35                  40                  45              


Asp Thr His Leu Ala Val Ser Gln Pro Leu Thr Glu Met Phe Thr Ser 
    50                  55                  60                  


Ser Phe Cys Lys Asn Asp Val Leu Pro Leu Ser Asn Ser Val Pro Glu 
65                  70                  75                  80  


Asp Val Gly Lys Ala Asp Gln Leu Lys Asp Glu Gly Asn Asn His Met 
                85                  90                  95      


Lys Glu Glu Asn Tyr Ala Ala Ala Val Asp Cys Tyr Thr Gln Ala Ile 
            100                 105                 110         


Glu Leu Asp Pro Asn Asn Ala Val Tyr Tyr Cys Asn Arg Ala Ala Ala 
        115                 120                 125             


Gln Ser Lys Leu Gly His Tyr Thr Asp Ala Ile Lys Asp Cys Glu Lys 
    130                 135                 140                 


Ala Ile Ala Ile Asp Ser Lys Tyr Ser Lys Ala Tyr Gly Arg Met Gly 
145                 150                 155                 160 


Leu Ala Leu Thr Ala Leu Asn Lys Phe Glu Glu Ala Val Thr Ser Tyr 
                165                 170                 175     


Gln Lys Ala Leu Asp Leu Asp Pro Glu Asn Asp Ser Tyr Lys Ser Asn 
            180                 185                 190         


Leu Lys Ile Ala Glu Gln Lys Leu Arg Glu Val Ser Ser Pro Thr Gly 
        195                 200                 205             


Thr Gly Leu Ser Phe Asp Met Ala Ser Leu Ile Asn Asn Pro Ala Phe 
    210                 215                 220                 


Ile Ser Met Ala Ala Ser Leu Met Gln Asn Pro Gln Val Gln Gln Leu 
225                 230                 235                 240 


Met Ser Gly Met Met Thr Asn Ala Ile Gly Gly Pro Ala Ala Gly Val 
                245                 250                 255     


Gly Gly Leu Thr Asp Leu Ser Ser Leu Ile Gln Ala Gly Gln Gln Phe 
            260                 265                 270         


Ala Gln Gln Ile Gln Gln Gln Asn Pro Glu Leu Ile Glu Gln Leu Arg 
        275                 280                 285             


Asn His Ile Arg Ser Arg Ser Phe Ser Ser Ser Ala Glu Glu His Ser 
    290                 295                 300                 


<210>  3854
<211>  427
<212>  PRT
<213>  homo sapiens

<400>  3854

Met Ala Glu Gln Asp Val Glu Asn Asp Leu Leu Asp Tyr Asp Glu Glu 
1               5                   10                  15      


Glu Glu Pro Gln Ala Pro Gln Glu Ser Thr Pro Ala Pro Pro Lys Lys 
            20                  25                  30          


Asp Ile Lys Gly Ser Tyr Val Ser Ile His Ser Ser Gly Phe Arg Asp 
        35                  40                  45              


Phe Leu Leu Lys Pro Glu Leu Leu Arg Ala Ile Val Asp Cys Gly Phe 
    50                  55                  60                  


Glu His Pro Ser Glu Val Gln His Glu Cys Ile Pro Gln Ala Ile Leu 
65                  70                  75                  80  


Gly Met Asp Val Leu Cys Gln Ala Lys Ser Gly Met Gly Lys Thr Ala 
                85                  90                  95      


Val Phe Val Leu Ala Thr Leu Gln Gln Ile Glu Pro Val Asn Gly Gln 
            100                 105                 110         


Val Thr Val Leu Val Met Cys His Thr Arg Glu Leu Ala Phe Gln Ile 
        115                 120                 125             


Ser Lys Glu Tyr Glu Arg Phe Ser Lys Tyr Met Pro Ser Val Lys Val 
    130                 135                 140                 


Ser Val Phe Phe Gly Gly Leu Ser Ile Lys Lys Asp Glu Glu Val Leu 
145                 150                 155                 160 


Lys Lys Asn Cys Pro His Val Val Val Gly Thr Pro Gly Arg Ile Leu 
                165                 170                 175     


Ala Leu Val Arg Asn Arg Ser Phe Ser Leu Lys Asn Val Lys His Phe 
            180                 185                 190         


Val Leu Asp Glu Cys Asp Lys Met Leu Glu Gln Leu Asp Met Arg Arg 
        195                 200                 205             


Asp Val Gln Glu Ile Phe Arg Leu Thr Pro His Glu Lys Gln Cys Met 
    210                 215                 220                 


Met Phe Ser Ala Thr Leu Ser Lys Asp Ile Arg Pro Val Cys Arg Lys 
225                 230                 235                 240 


Phe Met Gln Asp Pro Met Glu Val Phe Val Asp Asp Glu Thr Lys Leu 
                245                 250                 255     


Thr Leu His Gly Leu Gln Gln Tyr Tyr Val Lys Leu Lys Asp Ser Glu 
            260                 265                 270         


Lys Asn Arg Lys Leu Phe Asp Leu Leu Asp Val Leu Glu Phe Asn Gln 
        275                 280                 285             


Val Ile Ile Phe Val Lys Ser Val Gln Arg Cys Met Ala Leu Ala Gln 
    290                 295                 300                 


Leu Leu Val Glu Gln Asn Phe Pro Ala Ile Ala Ile His Arg Gly Met 
305                 310                 315                 320 


Ala Gln Glu Glu Arg Leu Ser Arg Tyr Gln Gln Phe Lys Asp Phe Gln 
                325                 330                 335     


Arg Arg Ile Leu Val Ala Thr Asn Leu Phe Gly Arg Gly Met Asp Ile 
            340                 345                 350         


Glu Arg Val Asn Ile Val Phe Asn Tyr Asp Met Pro Glu Asp Ser Asp 
        355                 360                 365             


Thr Tyr Leu His Arg Val Ala Arg Ala Gly Arg Phe Gly Thr Lys Gly 
    370                 375                 380                 


Leu Ala Ile Thr Phe Val Ser Asp Glu Asn Asp Ala Lys Ile Leu Asn 
385                 390                 395                 400 


Asp Val Gln Asp Arg Phe Glu Val Asn Val Ala Glu Leu Pro Glu Glu 
                405                 410                 415     


Ile Asp Ile Ser Thr Tyr Ile Glu Gln Ser Arg 
            420                 425         


<210>  3855
<211>  676
<212>  PRT
<213>  homo sapiens

<400>  3855

Met Ala Ala Asn Val Gly Ser Met Phe Gln Tyr Trp Lys Arg Phe Asp 
1               5                   10                  15      


Leu Gln Gln Leu Gln Arg Glu Leu Asp Ala Thr Ala Thr Val Leu Ala 
            20                  25                  30          


Asn Arg Gln Asp Glu Ser Glu Gln Ser Arg Lys Arg Leu Ile Glu Gln 
        35                  40                  45              


Ser Arg Glu Phe Lys Lys Asn Thr Pro Glu Asp Leu Arg Lys Gln Val 
    50                  55                  60                  


Ala Pro Leu Leu Lys Ser Phe Gln Gly Glu Ile Asp Ala Leu Ser Lys 
65                  70                  75                  80  


Arg Ser Lys Glu Ala Glu Ala Ala Phe Leu Asn Val Tyr Lys Arg Leu 
                85                  90                  95      


Ile Asp Val Pro Asp Pro Val Pro Ala Leu Asp Leu Gly Gln Gln Leu 
            100                 105                 110         


Gln Leu Lys Val Gln Arg Leu His Asp Ile Glu Thr Glu Asn Gln Lys 
        115                 120                 125             


Leu Arg Glu Thr Leu Glu Glu Tyr Asn Lys Glu Phe Ala Glu Val Lys 
    130                 135                 140                 


Asn Gln Glu Val Thr Ile Lys Ala Leu Lys Glu Lys Ile Arg Glu Tyr 
145                 150                 155                 160 


Glu Gln Thr Leu Lys Asn Gln Ala Glu Thr Ile Ala Leu Glu Lys Glu 
                165                 170                 175     


Gln Lys Leu Gln Asn Asp Phe Ala Glu Lys Glu Arg Lys Leu Gln Glu 
            180                 185                 190         


Thr Gln Met Ser Thr Thr Ser Lys Leu Glu Glu Ala Glu His Lys Val 
        195                 200                 205             


Gln Ser Leu Gln Thr Ala Leu Glu Lys Thr Arg Thr Glu Leu Phe Asp 
    210                 215                 220                 


Leu Lys Thr Lys Tyr Asp Glu Glu Thr Thr Ala Lys Ala Asp Glu Ile 
225                 230                 235                 240 


Glu Met Ile Met Thr Asp Leu Glu Arg Ala Asn Gln Arg Ala Glu Val 
                245                 250                 255     


Ala Gln Arg Glu Ala Glu Thr Leu Arg Glu Gln Leu Ser Ser Ala Asn 
            260                 265                 270         


His Ser Leu Gln Leu Ala Ser Gln Ile Gln Lys Ala Pro Asp Val Ala 
        275                 280                 285             


Ile Glu Val Leu Thr Arg Ser Ser Leu Glu Val Glu Leu Ala Ala Lys 
    290                 295                 300                 


Glu Arg Glu Ile Ala Gln Leu Val Glu Asp Val Gln Arg Leu Gln Ala 
305                 310                 315                 320 


Ser Leu Thr Lys Leu Arg Glu Asn Ser Ala Ser Gln Ile Ser Gln Leu 
                325                 330                 335     


Glu Gln Gln Leu Ser Ala Lys Asn Ser Thr Leu Lys Gln Leu Glu Glu 
            340                 345                 350         


Lys Leu Lys Gly Gln Ala Asp Tyr Glu Glu Val Lys Lys Glu Leu Asn 
        355                 360                 365             


Ile Leu Lys Ser Met Glu Phe Ala Pro Ser Glu Gly Ala Gly Thr Gln 
    370                 375                 380                 


Asp Ala Ala Lys Pro Leu Glu Val Leu Leu Leu Glu Lys Asn Arg Ser 
385                 390                 395                 400 


Leu Gln Ser Glu Asn Ala Ala Leu Arg Ile Ser Asn Ser Asp Leu Ser 
                405                 410                 415     


Gly Arg Cys Ala Glu Leu Gln Val Arg Ile Thr Glu Ala Val Ala Thr 
            420                 425                 430         


Ala Thr Glu Gln Arg Glu Leu Ile Ala Arg Leu Glu Gln Asp Leu Ser 
        435                 440                 445             


Ile Ile Gln Ser Ile Gln Arg Pro Asp Ala Glu Gly Ala Ala Glu His 
    450                 455                 460                 


Arg Leu Glu Lys Ile Pro Glu Pro Ile Lys Glu Ala Thr Ala Leu Phe 
465                 470                 475                 480 


Tyr Gly Pro Ala Ala Pro Ala Ser Gly Ala Leu Pro Glu Gly Gln Val 
                485                 490                 495     


Asp Ser Leu Leu Ser Ile Ile Ser Ser Gln Arg Glu Arg Phe Arg Ala 
            500                 505                 510         


Arg Asn Gln Glu Leu Glu Ala Glu Asn Arg Leu Ala Gln His Thr Leu 
        515                 520                 525             


Gln Ala Leu Gln Ser Glu Leu Asp Ser Leu Arg Ala Asp Asn Ile Lys 
    530                 535                 540                 


Leu Phe Glu Lys Ile Lys Phe Leu Gln Ser Tyr Pro Gly Arg Gly Ser 
545                 550                 555                 560 


Gly Ser Asp Asp Thr Glu Leu Arg Tyr Ser Ser Gln Tyr Glu Glu Arg 
                565                 570                 575     


Leu Asp Pro Phe Ser Ser Phe Ser Lys Arg Glu Arg Gln Arg Lys Tyr 
            580                 585                 590         


Leu Ser Leu Ser Pro Trp Asp Lys Ala Thr Leu Ser Met Gly Arg Leu 
        595                 600                 605             


Val Leu Ser Asn Lys Met Ala Arg Thr Ile Gly Phe Phe Tyr Thr Leu 
    610                 615                 620                 


Phe Leu His Cys Leu Val Phe Leu Val Leu Tyr Lys Leu Ala Trp Ser 
625                 630                 635                 640 


Glu Ser Met Glu Arg Asp Cys Ala Thr Phe Cys Ala Lys Lys Phe Ala 
                645                 650                 655     


Asp His Leu His Lys Phe His Glu Asn Asp Asn Gly Ala Ala Ala Gly 
            660                 665                 670         


Asp Leu Trp Gln 
        675     


<210>  3856
<211>  431
<212>  PRT
<213>  homo sapiens

<400>  3856

Met Leu Ala Leu Leu Ala Ala Ser Val Ala Leu Ala Val Ala Ala Gly 
1               5                   10                  15      


Ala Gln Asp Ser Pro Ala Pro Gly Ser Arg Phe Val Cys Thr Ala Leu 
            20                  25                  30          


Pro Pro Glu Ala Val His Ala Gly Cys Pro Leu Pro Ala Met Pro Met 
        35                  40                  45              


Gln Gly Gly Ala Gln Ser Pro Glu Glu Glu Leu Arg Ala Ala Val Leu 
    50                  55                  60                  


Gln Leu Arg Glu Thr Val Val Gln Gln Lys Glu Thr Leu Gly Ala Gln 
65                  70                  75                  80  


Arg Glu Ala Ile Arg Glu Leu Thr Gly Lys Leu Ala Arg Cys Glu Gly 
                85                  90                  95      


Leu Ala Gly Gly Lys Ala Arg Gly Ala Gly Ala Thr Gly Lys Asp Thr 
            100                 105                 110         


Met Gly Asp Leu Pro Arg Asp Pro Gly His Val Val Glu Gln Leu Ser 
        115                 120                 125             


Arg Ser Leu Gln Thr Leu Lys Asp Arg Leu Glu Ser Leu Glu His Gln 
    130                 135                 140                 


Leu Arg Ala Asn Val Ser Asn Ala Gly Leu Pro Gly Asp Phe Arg Glu 
145                 150                 155                 160 


Val Leu Gln Gln Arg Leu Gly Glu Leu Glu Arg Gln Leu Leu Arg Lys 
                165                 170                 175     


Val Ala Glu Leu Glu Asp Glu Lys Ser Leu Leu His Asn Glu Thr Ser 
            180                 185                 190         


Ala His Arg Gln Lys Thr Glu Ser Thr Leu Asn Ala Leu Leu Gln Arg 
        195                 200                 205             


Val Thr Glu Leu Glu Arg Gly Asn Ser Ala Phe Lys Ser Pro Asp Ala 
    210                 215                 220                 


Phe Lys Val Ser Leu Pro Leu Arg Thr Asn Tyr Leu Tyr Gly Lys Ile 
225                 230                 235                 240 


Lys Lys Thr Leu Pro Glu Leu Tyr Ala Phe Thr Ile Cys Leu Trp Leu 
                245                 250                 255     


Arg Ser Ser Ala Ser Pro Gly Ile Gly Thr Pro Phe Ser Tyr Ala Val 
            260                 265                 270         


Pro Gly Gln Ala Asn Glu Ile Val Leu Ile Glu Trp Gly Asn Asn Pro 
        275                 280                 285             


Ile Glu Leu Leu Ile Asn Asp Lys Val Ala Gln Leu Pro Leu Phe Val 
    290                 295                 300                 


Ser Asp Gly Lys Trp His His Ile Cys Val Thr Trp Thr Thr Arg Asp 
305                 310                 315                 320 


Gly Met Trp Glu Ala Phe Gln Asp Gly Glu Lys Leu Gly Thr Gly Glu 
                325                 330                 335     


Asn Leu Ala Pro Trp His Pro Ile Lys Pro Gly Gly Val Leu Ile Leu 
            340                 345                 350         


Gly Gln Glu Gln Asp Thr Val Gly Gly Arg Phe Asp Ala Thr Gln Ala 
        355                 360                 365             


Phe Val Gly Glu Leu Ser Gln Phe Asn Ile Trp Asp Arg Val Leu Arg 
    370                 375                 380                 


Ala Gln Glu Ile Val Asn Ile Ala Asn Cys Ser Thr Asn Met Pro Gly 
385                 390                 395                 400 


Asn Ile Ile Pro Trp Val Asp Asn Asn Val Asp Val Phe Gly Gly Ala 
                405                 410                 415     


Ser Lys Trp Pro Val Glu Thr Cys Glu Glu Arg Leu Leu Asp Leu 
            420                 425                 430     


<210>  3857
<211>  539
<212>  PRT
<213>  homo sapiens

<400>  3857

Met Ala Thr Ser Ala Pro Leu Arg Ser Leu Glu Glu Glu Val Thr Cys 
1               5                   10                  15      


Ser Ile Cys Leu Asp Tyr Leu Arg Asp Pro Val Thr Ile Asp Cys Gly 
            20                  25                  30          


His Val Phe Cys Arg Ser Cys Thr Thr Asp Val Arg Pro Ile Ser Gly 
        35                  40                  45              


Ser Arg Pro Val Cys Pro Leu Cys Lys Lys Pro Phe Lys Lys Glu Asn 
    50                  55                  60                  


Ile Arg Pro Val Trp Gln Leu Ala Ser Leu Val Glu Asn Ile Glu Arg 
65                  70                  75                  80  


Leu Lys Val Asp Lys Gly Arg Gln Pro Gly Glu Val Thr Arg Glu Gln 
                85                  90                  95      


Gln Asp Ala Lys Leu Cys Glu Arg His Arg Glu Lys Leu His Tyr Tyr 
            100                 105                 110         


Cys Glu Asp Asp Gly Lys Leu Leu Cys Val Met Cys Arg Glu Ser Arg 
        115                 120                 125             


Glu His Arg Pro His Thr Ala Val Leu Met Glu Lys Ala Ala Gln Pro 
    130                 135                 140                 


His Arg Glu Lys Ile Leu Asn His Leu Ser Thr Leu Arg Arg Asp Arg 
145                 150                 155                 160 


Asp Lys Ile Gln Gly Phe Gln Ala Lys Gly Glu Ala Asp Ile Leu Ala 
                165                 170                 175     


Ala Leu Lys Lys Leu Gln Asp Gln Arg Gln Tyr Ile Val Ala Glu Phe 
            180                 185                 190         


Glu Gln Gly His Gln Phe Leu Arg Glu Arg Glu Glu His Leu Leu Glu 
        195                 200                 205             


Gln Leu Ala Lys Leu Glu Gln Glu Leu Thr Glu Gly Arg Glu Lys Phe 
    210                 215                 220                 


Lys Ser Arg Gly Val Gly Glu Leu Ala Arg Leu Ala Leu Val Ile Ser 
225                 230                 235                 240 


Glu Leu Glu Gly Lys Ala Gln Gln Pro Ala Ala Glu Leu Met Gln Asp 
                245                 250                 255     


Thr Arg Asp Phe Leu Asn Arg Tyr Pro Arg Lys Lys Phe Trp Val Gly 
            260                 265                 270         


Lys Pro Ile Ala Arg Val Val Lys Lys Lys Thr Gly Glu Phe Ser Asp 
        275                 280                 285             


Lys Leu Leu Ser Leu Gln Arg Gly Leu Arg Glu Phe Gln Gly Lys Leu 
    290                 295                 300                 


Leu Arg Asp Leu Glu Tyr Lys Thr Val Ser Val Thr Leu Asp Pro Gln 
305                 310                 315                 320 


Ser Ala Ser Gly Tyr Leu Gln Leu Ser Glu Asp Trp Lys Cys Val Thr 
                325                 330                 335     


Tyr Thr Ser Leu Tyr Lys Ser Ala Tyr Leu His Pro Gln Gln Phe Asp 
            340                 345                 350         


Cys Glu Pro Gly Val Leu Gly Ser Lys Gly Phe Thr Trp Gly Lys Val 
        355                 360                 365             


Tyr Trp Glu Val Glu Val Glu Arg Glu Gly Trp Ser Glu Asp Glu Glu 
    370                 375                 380                 


Glu Gly Asp Glu Glu Glu Glu Gly Glu Glu Glu Glu Glu Glu Glu Glu 
385                 390                 395                 400 


Ala Gly Tyr Gly Asp Gly Tyr Asp Asp Trp Glu Thr Asp Glu Asp Glu 
                405                 410                 415     


Glu Ser Leu Gly Asp Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu 
            420                 425                 430         


Val Leu Glu Ser Cys Met Val Gly Val Ala Arg Asp Ser Val Lys Arg 
        435                 440                 445             


Lys Gly Asp Leu Ser Leu Arg Pro Glu Asp Gly Val Trp Ala Leu Arg 
    450                 455                 460                 


Leu Ser Ser Ser Gly Ile Trp Ala Asn Thr Ser Pro Glu Ala Glu Leu 
465                 470                 475                 480 


Phe Pro Ala Leu Arg Pro Arg Arg Val Gly Ile Ala Leu Asp Tyr Glu 
                485                 490                 495     


Gly Gly Thr Val Thr Phe Thr Asn Ala Glu Ser Gln Glu Leu Ile Tyr 
            500                 505                 510         


Thr Phe Thr Ala Thr Phe Thr Arg Arg Leu Val Pro Phe Leu Trp Leu 
        515                 520                 525             


Lys Trp Pro Gly Thr Arg Leu Leu Leu Arg Pro 
    530                 535                 


<210>  3858
<211>  290
<212>  PRT
<213>  homo sapiens

<400>  3858

Met Ser Asn Lys Glu Gly Ser Gly Gly Phe Arg Lys Arg Lys His Asp 
1               5                   10                  15      


Asn Phe Pro His Asn Gln Arg Arg Glu Gly Lys Asp Val Asn Ser Ser 
            20                  25                  30          


Ser Pro Val Met Leu Ala Phe Lys Ser Phe Gln Gln Glu Leu Asp Ala 
        35                  40                  45              


Arg His Asp Lys Tyr Glu Arg Leu Val Lys Leu Ser Arg Asp Ile Thr 
    50                  55                  60                  


Val Glu Ser Lys Arg Thr Ile Phe Leu Leu His Arg Ile Thr Ser Ala 
65                  70                  75                  80  


Pro Asp Met Glu Asp Ile Leu Thr Glu Ser Glu Ile Lys Leu Asp Gly 
                85                  90                  95      


Val Arg Gln Lys Ile Phe Gln Val Ala Gln Glu Leu Ser Gly Glu Asp 
            100                 105                 110         


Met His Gln Phe His Arg Ala Ile Thr Thr Gly Leu Gln Glu Tyr Val 
        115                 120                 125             


Glu Ala Val Ser Phe Gln His Phe Ile Lys Thr Arg Ser Leu Ile Ser 
    130                 135                 140                 


Met Asp Glu Ile Asn Lys Gln Leu Ile Phe Thr Thr Glu Asp Asn Gly 
145                 150                 155                 160 


Lys Glu Asn Lys Thr Pro Ser Ser Asp Ala Gln Asp Lys Gln Phe Gly 
                165                 170                 175     


Thr Trp Arg Leu Arg Val Thr Pro Val Asp Tyr Leu Leu Gly Val Ala 
            180                 185                 190         


Asp Leu Thr Gly Glu Leu Met Arg Met Cys Ile Asn Ser Val Gly Asn 
        195                 200                 205             


Gly Asp Ile Asp Thr Pro Phe Glu Val Ser Gln Phe Leu Arg Gln Val 
    210                 215                 220                 


Tyr Asp Gly Phe Ser Phe Ile Gly Asn Thr Gly Pro Tyr Glu Val Ser 
225                 230                 235                 240 


Lys Lys Leu Tyr Thr Leu Lys Gln Ser Leu Ala Lys Val Glu Asn Ala 
                245                 250                 255     


Cys Tyr Ala Leu Lys Val Arg Gly Ser Glu Ile Pro Lys His Met Leu 
            260                 265                 270         


Ala Asp Val Phe Ser Val Lys Thr Glu Met Ile Asp Gln Glu Glu Gly 
        275                 280                 285             


Ile Ser 
    290 


<210>  3859
<211>  3477
<212>  PRT
<213>  homo sapiens

<400>  3859

Met Ala Asn Arg Arg Val Gly Arg Gly Cys Trp Glu Val Ser Pro Thr 
1               5                   10                  15      


Glu Arg Arg Pro Pro Ala Gly Leu Arg Gly Pro Ala Ala Glu Glu Glu 
            20                  25                  30          


Ala Ser Ser Pro Pro Val Leu Ser Leu Ser His Phe Cys Arg Ser Pro 
        35                  40                  45              


Phe Leu Cys Phe Gly Asp Val Leu Leu Gly Ala Ser Arg Thr Leu Ser 
    50                  55                  60                  


Leu Ala Leu Asp Asn Pro Asn Glu Glu Val Ala Glu Val Lys Ile Ser 
65                  70                  75                  80  


His Phe Pro Ala Ala Asp Leu Gly Phe Ser Val Ser Gln Arg Cys Phe 
                85                  90                  95      


Val Leu Gln Pro Lys Glu Lys Ile Val Ile Ser Val Asn Trp Thr Pro 
            100                 105                 110         


Leu Lys Glu Gly Arg Val Arg Glu Ile Met Thr Phe Leu Val Asn Asp 
        115                 120                 125             


Val Leu Lys His Gln Ala Ile Leu Leu Gly Asn Ala Glu Glu Gln Lys 
    130                 135                 140                 


Lys Lys Lys Arg Ser Leu Trp Asp Thr Ile Lys Lys Lys Lys Ile Ser 
145                 150                 155                 160 


Ala Ser Thr Ser His Asn Arg Arg Val Ser Asn Ile Gln Asn Val Asn 
                165                 170                 175     


Lys Thr Phe Ser Val Ser Gln Lys Val Asp Arg Val Arg Ser Pro Leu 
            180                 185                 190         


Gln Ala Cys Glu Asn Leu Ala Met Asn Glu Gly Gly Pro Pro Thr Glu 
        195                 200                 205             


Asn Asn Ser Leu Ile Leu Glu Glu Asn Lys Ile Pro Ile Ser Pro Ile 
    210                 215                 220                 


Ser Pro Ala Phe Asn Glu Cys His Gly Ala Thr Cys Leu Pro Leu Ser 
225                 230                 235                 240 


Val Arg Arg Ser Thr Thr Tyr Ser Ser Leu His Ala Ser Glu Asn Arg 
                245                 250                 255     


Glu Leu Leu Asn Val His Ser Ala Asn Val Ser Lys Val Ser Phe Asn 
            260                 265                 270         


Glu Lys Ala Val Thr Glu Thr Ser Phe Asn Ser Val Asn Val Asn Gly 
        275                 280                 285             


Gln Arg Gly Glu Asn Ser Lys Leu Ser Leu Thr Pro Asn Cys Ser Ser 
    290                 295                 300                 


Thr Leu Asn Ile Thr Gln Ser Gln Ile His Phe Leu Ser Pro Asp Ser 
305                 310                 315                 320 


Phe Val Asn Asn Ser His Gly Ala Asn Asn Glu Leu Glu Leu Val Thr 
                325                 330                 335     


Cys Leu Ser Ser Asp Met Phe Met Lys Asp Asn Ser Gln Pro Val His 
            340                 345                 350         


Leu Glu Ser Thr Ile Ala His Glu Ile Tyr Gln Lys Ile Leu Ser Pro 
        355                 360                 365             


Asp Ser Phe Ile Lys Asp Asn Tyr Gly Leu Asn Gln Asp Leu Glu Ser 
    370                 375                 380                 


Glu Ser Val Asn Pro Ile Leu Ser Pro Asn Gln Phe Leu Lys Asp Asn 
385                 390                 395                 400 


Met Ala Tyr Met Cys Thr Ser Gln Gln Thr Cys Lys Val Pro Leu Ser 
                405                 410                 415     


Asn Glu Asn Ser Gln Val Pro Gln Ser Pro Glu Asp Trp Arg Lys Ser 
            420                 425                 430         


Glu Val Ser Pro Arg Ile Pro Glu Cys Gln Gly Ser Lys Ser Pro Lys 
        435                 440                 445             


Ala Ile Phe Glu Glu Leu Val Glu Met Lys Ser Asn Tyr Tyr Ser Phe 
    450                 455                 460                 


Ile Lys Gln Asn Asn Pro Lys Phe Ser Ala Val Gln Asp Ile Ser Ser 
465                 470                 475                 480 


His Ser His Asn Lys Gln Pro Lys Arg Arg Pro Ile Leu Ser Ala Thr 
                485                 490                 495     


Val Thr Lys Arg Lys Ala Thr Cys Thr Arg Glu Asn Gln Thr Glu Ile 
            500                 505                 510         


Asn Lys Pro Lys Ala Lys Arg Cys Leu Asn Ser Ala Val Gly Glu His 
        515                 520                 525             


Glu Lys Val Ile Asn Asn Gln Lys Glu Lys Glu Asp Phe His Ser Tyr 
    530                 535                 540                 


Leu Pro Ile Ile Asp Pro Ile Leu Ser Lys Ser Lys Ser Tyr Lys Asn 
545                 550                 555                 560 


Glu Val Thr Pro Ser Ser Thr Thr Ala Ser Val Ala Arg Lys Arg Lys 
                565                 570                 575     


Ser Asp Gly Ser Met Glu Asp Ala Asn Val Arg Val Ala Ile Thr Glu 
            580                 585                 590         


His Thr Glu Val Arg Glu Ile Lys Arg Ile His Phe Ser Pro Ser Glu 
        595                 600                 605             


Pro Lys Thr Ser Ala Val Lys Lys Thr Lys Asn Val Thr Thr Pro Ile 
    610                 615                 620                 


Ser Lys Arg Ile Ser Asn Arg Glu Lys Leu Asn Leu Lys Lys Lys Thr 
625                 630                 635                 640 


Asp Leu Ser Ile Phe Arg Thr Pro Ile Ser Lys Thr Asn Lys Arg Thr 
                645                 650                 655     


Lys Pro Ile Ile Ala Val Ala Gln Ser Ser Leu Thr Phe Ile Lys Pro 
            660                 665                 670         


Leu Lys Thr Asp Ile Pro Arg His Pro Met Pro Phe Ala Ala Lys Asn 
        675                 680                 685             


Met Phe Tyr Asp Glu Arg Trp Lys Glu Lys Gln Glu Gln Gly Phe Thr 
    690                 695                 700                 


Trp Trp Leu Asn Phe Ile Leu Thr Pro Asp Asp Phe Thr Val Lys Thr 
705                 710                 715                 720 


Asn Ile Ser Glu Val Asn Ala Ala Thr Leu Leu Leu Gly Ile Glu Asn 
                725                 730                 735     


Gln His Lys Ile Ser Val Pro Arg Ala Pro Thr Lys Glu Glu Met Ser 
            740                 745                 750         


Leu Arg Ala Tyr Thr Ala Arg Cys Arg Leu Asn Arg Leu Arg Arg Ala 
        755                 760                 765             


Ala Cys Arg Leu Phe Thr Ser Glu Lys Met Val Lys Ala Ile Lys Lys 
    770                 775                 780                 


Leu Glu Ile Glu Ile Glu Ala Arg Arg Leu Ile Val Arg Lys Asp Arg 
785                 790                 795                 800 


His Leu Trp Lys Asp Val Gly Glu Arg Gln Lys Val Leu Asn Trp Leu 
                805                 810                 815     


Leu Ser Tyr Asn Pro Leu Trp Leu Arg Ile Gly Leu Glu Thr Thr Tyr 
            820                 825                 830         


Gly Glu Leu Ile Ser Leu Glu Asp Asn Ser Asp Val Thr Gly Leu Ala 
        835                 840                 845             


Met Phe Ile Leu Asn Arg Leu Leu Trp Asn Pro Asp Ile Ala Ala Glu 
    850                 855                 860                 


Tyr Arg His Pro Thr Val Pro His Leu Tyr Arg Asp Gly His Glu Glu 
865                 870                 875                 880 


Ala Leu Ser Lys Phe Thr Leu Lys Lys Leu Leu Leu Leu Val Cys Phe 
                885                 890                 895     


Leu Asp Tyr Ala Lys Ile Ser Arg Leu Ile Asp His Asp Pro Cys Leu 
            900                 905                 910         


Phe Cys Lys Asp Ala Glu Phe Lys Ala Ser Lys Glu Ile Leu Leu Ala 
        915                 920                 925             


Phe Ser Arg Asp Phe Leu Ser Gly Glu Gly Asp Leu Ser Arg His Leu 
    930                 935                 940                 


Gly Leu Leu Gly Leu Pro Val Asn His Val Gln Thr Pro Phe Asp Glu 
945                 950                 955                 960 


Phe Asp Phe Ala Val Thr Asn Leu Ala Val Asp Leu Gln Cys Gly Val 
                965                 970                 975     


Arg Leu Val Arg Thr Met Glu Leu Leu Thr Gln Asn Trp Asp Leu Ser 
            980                 985                 990         


Lys Lys Leu Arg Ile Pro Ala Ile  Ser Arg Leu Gln Lys  Met His Asn 
        995                 1000                 1005             


Val Asp  Ile Val Leu Gln Val  Leu Lys Ser Arg Gly  Ile Glu Leu 
    1010                 1015                 1020             


Ser Asp  Glu His Gly Asn Thr  Ile Leu Ser Lys Asp  Ile Val Asp 
    1025                 1030                 1035             


Arg His  Arg Glu Lys Thr Leu  Arg Leu Leu Trp Lys  Ile Ala Phe 
    1040                 1045                 1050             


Ala Phe  Gln Val Asp Ile Ser  Leu Asn Leu Asp Gln  Leu Lys Glu 
    1055                 1060                 1065             


Glu Ile  Ala Phe Leu Lys His  Thr Lys Ser Ile Lys  Lys Thr Ile 
    1070                 1075                 1080             


Ser Leu  Leu Ser Cys His Ser  Asp Asp Leu Ile Asn  Lys Lys Lys 
    1085                 1090                 1095             


Gly Lys  Arg Asp Ser Gly Ser  Phe Glu Gln Tyr Ser  Glu Asn Ile 
    1100                 1105                 1110             


Lys Leu  Leu Met Asp Trp Val  Asn Ala Val Cys Ala  Phe Tyr Asn 
    1115                 1120                 1125             


Lys Lys  Val Glu Asn Phe Thr  Val Ser Phe Ser Asp  Gly Arg Val 
    1130                 1135                 1140             


Leu Cys  Tyr Leu Ile His His  Tyr His Pro Cys Tyr  Val Pro Phe 
    1145                 1150                 1155             


Asp Ala  Ile Cys Gln Arg Thr  Thr Gln Thr Val Glu  Cys Thr Gln 
    1160                 1165                 1170             


Thr Gly  Ser Val Val Leu Asn  Ser Ser Ser Glu Ser  Asp Asp Ser 
    1175                 1180                 1185             


Ser Leu  Asp Met Ser Leu Lys  Ala Phe Asp His Glu  Asn Thr Ser 
    1190                 1195                 1200             


Glu Leu  Tyr Lys Glu Leu Leu  Glu Asn Glu Lys Lys  Asn Phe His 
    1205                 1210                 1215             


Leu Val  Arg Ser Ala Val Arg  Asp Leu Gly Gly Ile  Pro Ala Met 
    1220                 1225                 1230             


Ile Asn  His Ser Asp Met Ser  Asn Thr Ile Pro Asp  Glu Lys Val 
    1235                 1240                 1245             


Val Ile  Thr Tyr Leu Ser Phe  Leu Cys Ala Arg Leu  Leu Asp Leu 
    1250                 1255                 1260             


Arg Lys  Glu Ile Arg Ala Ala  Arg Leu Ile Gln Thr  Thr Trp Arg 
    1265                 1270                 1275             


Lys Tyr  Lys Leu Lys Thr Asp  Leu Lys Arg His Gln  Glu Arg Glu 
    1280                 1285                 1290             


Lys Ala  Ala Arg Ile Ile Gln  Leu Ala Val Ile Asn  Phe Leu Ala 
    1295                 1300                 1305             


Lys Gln  Arg Leu Arg Lys Arg  Val Asn Ala Ala Leu  Val Ile Gln 
    1310                 1315                 1320             


Lys Tyr  Trp Arg Arg Val Leu  Ala Gln Arg Lys Leu  Leu Met Leu 
    1325                 1330                 1335             


Lys Lys  Glu Lys Leu Glu Lys  Val Gln Asn Lys Ala  Ala Ser Leu 
    1340                 1345                 1350             


Ile Gln  Gly Tyr Trp Arg Arg  Tyr Ser Thr Arg Gln  Arg Phe Leu 
    1355                 1360                 1365             


Lys Leu  Lys Tyr Tyr Ser Ile  Ile Leu Gln Ser Arg  Ile Arg Met 
    1370                 1375                 1380             


Ile Ile  Ala Val Thr Ser Tyr  Lys Arg Tyr Leu Trp  Ala Thr Val 
    1385                 1390                 1395             


Thr Ile  Gln Arg His Trp Arg  Ala Tyr Leu Arg Arg  Lys Gln Asp 
    1400                 1405                 1410             


Gln Gln  Arg Tyr Glu Met Leu  Lys Ser Ser Thr Leu  Ile Ile Gln 
    1415                 1420                 1425             


Ser Met  Phe Arg Lys Trp Lys  Gln Arg Lys Met Gln  Ser Gln Val 
    1430                 1435                 1440             


Lys Ala  Thr Val Ile Leu Gln  Arg Ala Phe Arg Glu  Trp His Leu 
    1445                 1450                 1455             


Arg Lys  Gln Ala Lys Glu Glu  Asn Ser Ala Ile Ile  Ile Gln Ser 
    1460                 1465                 1470             


Trp Tyr  Arg Met His Lys Glu  Leu Arg Lys Tyr Ile  Tyr Ile Arg 
    1475                 1480                 1485             


Ser Cys  Val Val Ile Ile Gln  Lys Arg Phe Arg Cys  Phe Gln Ala 
    1490                 1495                 1500             


Gln Lys  Leu Tyr Lys Arg Arg  Lys Glu Ser Ile Leu  Thr Ile Gln 
    1505                 1510                 1515             


Lys Tyr  Tyr Lys Ala Tyr Leu  Lys Gly Lys Ile Glu  Arg Thr Asn 
    1520                 1525                 1530             


Tyr Leu  Gln Lys Arg Ala Ala  Ala Ile Gln Leu Gln  Ala Ala Phe 
    1535                 1540                 1545             


Arg Arg  Leu Lys Ala His Asn  Leu Cys Arg Gln Ile  Arg Ala Ala 
    1550                 1555                 1560             


Cys Val  Ile Gln Ser Tyr Trp  Arg Met Arg Gln Asp  Arg Val Arg 
    1565                 1570                 1575             


Phe Leu  Asn Leu Lys Lys Thr  Ile Ile Lys Phe Gln  Ala His Val 
    1580                 1585                 1590             


Arg Lys  His Gln Gln Arg Gln  Lys Tyr Lys Lys Met  Lys Lys Ala 
    1595                 1600                 1605             


Ala Val  Ile Ile Gln Thr His  Phe Arg Ala Tyr Ile  Phe Ala Met 
    1610                 1615                 1620             


Lys Val  Leu Ala Ser Tyr Gln  Lys Thr Arg Ser Ala  Val Ile Val 
    1625                 1630                 1635             


Leu Gln  Ser Ala Tyr Arg Gly  Met Gln Ala Arg Lys  Met Tyr Ile 
    1640                 1645                 1650             


His Ile  Leu Thr Ser Val Ile  Lys Ile Gln Ser Tyr  Tyr Arg Ala 
    1655                 1660                 1665             


Tyr Val  Ser Lys Lys Glu Phe  Leu Ser Leu Lys Asn  Ala Thr Ile 
    1670                 1675                 1680             


Lys Leu  Gln Ser Thr Val Lys  Met Lys Gln Thr Arg  Lys Gln Tyr 
    1685                 1690                 1695             


Leu His  Leu Arg Ala Ala Ala  Leu Phe Ile Gln Gln  Cys Tyr Arg 
    1700                 1705                 1710             


Ser Lys  Lys Ile Ala Ala Gln  Lys Arg Glu Glu Tyr  Met Gln Met 
    1715                 1720                 1725             


Arg Glu  Ser Cys Ile Lys Leu  Gln Ala Phe Val Arg  Gly Tyr Leu 
    1730                 1735                 1740             


Val Arg  Lys Gln Met Arg Leu  Gln Arg Lys Ala Val  Ile Ser Leu 
    1745                 1750                 1755             


Gln Ser  Tyr Phe Arg Met Arg  Lys Ala Arg Gln Tyr  Tyr Leu Lys 
    1760                 1765                 1770             


Met Tyr  Lys Ala Ile Ile Val  Ile Gln Asn Tyr Tyr  His Ala Tyr 
    1775                 1780                 1785             


Lys Ala  Gln Val Asn Gln Arg  Lys Asn Phe Leu Gln  Val Lys Lys 
    1790                 1795                 1800             


Ala Ala  Thr Cys Leu Gln Ala  Ala Tyr Arg Gly Tyr  Lys Val Arg 
    1805                 1810                 1815             


Gln Leu  Ile Lys Gln Gln Ser  Ile Ala Ala Leu Lys  Ile Gln Ser 
    1820                 1825                 1830             


Ala Phe  Arg Gly Tyr Asn Lys  Arg Val Lys Tyr Gln  Ser Val Leu 
    1835                 1840                 1845             


Gln Ser  Ile Ile Lys Ile Gln  Arg Trp Tyr Arg Ala  Tyr Lys Thr 
    1850                 1855                 1860             


Leu His  Asp Thr Arg Thr His  Phe Leu Lys Thr Lys  Ala Ala Val 
    1865                 1870                 1875             


Ile Ser  Leu Gln Ser Ala Tyr  Arg Gly Trp Lys Val  Arg Lys Gln 
    1880                 1885                 1890             


Ile Arg  Arg Glu His Gln Ala  Ala Leu Lys Ile Gln  Ser Ala Phe 
    1895                 1900                 1905             


Arg Met  Ala Lys Ala Gln Lys  Gln Phe Arg Leu Phe  Lys Thr Ala 
    1910                 1915                 1920             


Ala Leu  Val Ile Gln Gln Asn  Phe Arg Ala Trp Thr  Ala Gly Arg 
    1925                 1930                 1935             


Lys Gln  Cys Met Glu Tyr Ile  Glu Leu Arg His Ala  Val Leu Val 
    1940                 1945                 1950             


Leu Gln  Ser Met Trp Lys Gly  Lys Thr Leu Arg Arg  Gln Leu Gln 
    1955                 1960                 1965             


Arg Gln  His Lys Cys Ala Ile  Ile Ile Gln Ser Tyr  Tyr Arg Met 
    1970                 1975                 1980             


His Val  Gln Gln Lys Lys Trp  Lys Ile Met Lys Lys  Ala Ala Leu 
    1985                 1990                 1995             


Leu Ile  Gln Lys Tyr Tyr Arg  Ala Tyr Ser Ile Gly  Arg Glu Gln 
    2000                 2005                 2010             


Asn His  Leu Tyr Leu Lys Thr  Lys Ala Ala Val Val  Thr Leu Gln 
    2015                 2020                 2025             


Ser Ala  Tyr Arg Gly Met Lys  Val Arg Lys Arg Ile  Lys Asp Cys 
    2030                 2035                 2040             


Asn Lys  Ala Ala Val Thr Ile  Gln Ser Lys Tyr Arg  Ala Tyr Lys 
    2045                 2050                 2055             


Thr Lys  Lys Lys Tyr Ala Thr  Tyr Arg Ala Ser Ala  Ile Ile Ile 
    2060                 2065                 2070             


Gln Arg  Trp Tyr Arg Gly Ile  Lys Ile Thr Asn His  Gln His Lys 
    2075                 2080                 2085             


Glu Tyr  Leu Asn Leu Lys Lys  Thr Ala Ile Lys Ile  Gln Ser Val 
    2090                 2095                 2100             


Tyr Arg  Gly Ile Arg Val Arg  Arg His Ile Gln His  Met His Arg 
    2105                 2110                 2115             


Ala Ala  Thr Phe Ile Lys Ala  Met Phe Lys Met His  Gln Ser Arg 
    2120                 2125                 2130             


Ile Ser  Tyr His Thr Met Arg  Lys Ala Ala Ile Val  Ile Gln Val 
    2135                 2140                 2145             


Arg Cys  Arg Ala Tyr Tyr Gln  Gly Lys Met Gln Arg  Glu Lys Tyr 
    2150                 2155                 2160             


Leu Thr  Ile Leu Lys Ala Val  Lys Val Leu Gln Ala  Ser Phe Arg 
    2165                 2170                 2175             


Gly Val  Arg Val Arg Arg Thr  Leu Arg Lys Met Gln  Thr Ala Ala 
    2180                 2185                 2190             


Thr Leu  Ile Gln Ser Asn Tyr  Arg Arg Tyr Arg Gln  Gln Thr Tyr 
    2195                 2200                 2205             


Phe Asn  Lys Leu Lys Lys Ile  Thr Lys Thr Val Gln  Gln Arg Tyr 
    2210                 2215                 2220             


Trp Ala  Met Lys Glu Arg Asn  Ile Gln Phe Gln Arg  Tyr Asn Lys 
    2225                 2230                 2235             


Leu Arg  His Ser Val Ile Tyr  Ile Gln Ala Ile Phe  Arg Gly Lys 
    2240                 2245                 2250             


Lys Ala  Arg Arg His Leu Lys  Met Met His Ile Ala  Ala Thr Leu 
    2255                 2260                 2265             


Ile Gln  Arg Arg Phe Arg Thr  Leu Met Met Arg Arg  Arg Phe Leu 
    2270                 2275                 2280             


Ser Leu  Lys Lys Thr Ala Ile  Leu Ile Gln Arg Lys  Tyr Arg Ala 
    2285                 2290                 2295             


His Leu  Cys Thr Lys His His  Leu Gln Phe Leu Gln  Val Gln Asn 
    2300                 2305                 2310             


Ala Val  Ile Lys Ile Gln Ser  Ser Tyr Arg Arg Trp  Met Ile Arg 
    2315                 2320                 2325             


Lys Arg  Met Arg Glu Met His  Arg Ala Ala Thr Phe  Ile Gln Ser 
    2330                 2335                 2340             


Thr Phe  Arg Met His Arg Leu  His Met Arg Tyr Gln  Ala Leu Lys 
    2345                 2350                 2355             


Gln Ala  Ser Val Val Ile Gln  Gln Gln Tyr Gln Ala  Asn Arg Ala 
    2360                 2365                 2370             


Ala Lys  Leu Gln Arg Gln His  Tyr Leu Arg Gln Arg  His Ser Ala 
    2375                 2380                 2385             


Val Ile  Leu Gln Ala Ala Phe  Arg Gly Met Lys Thr  Arg Arg His 
    2390                 2395                 2400             


Leu Lys  Ser Met His Ser Ser  Ala Thr Leu Ile Gln  Ser Arg Phe 
    2405                 2410                 2415             


Arg Ser  Leu Leu Val Arg Arg  Arg Phe Ile Ser Leu  Lys Lys Ala 
    2420                 2425                 2430             


Thr Ile  Phe Val Gln Arg Lys  Tyr Arg Ala Thr Ile  Cys Ala Lys 
    2435                 2440                 2445             


His Lys  Leu Tyr Gln Phe Leu  His Leu Arg Lys Ala  Ala Ile Thr 
    2450                 2455                 2460             


Ile Gln  Ser Ser Tyr Arg Arg  Leu Met Val Lys Lys  Lys Leu Gln 
    2465                 2470                 2475             


Glu Met  Gln Arg Ala Ala Val  Leu Ile Gln Ala Thr  Phe Arg Met 
    2480                 2485                 2490             


Tyr Arg  Thr Tyr Ile Thr Phe  Gln Thr Trp Lys His  Ala Ser Ile 
    2495                 2500                 2505             


Leu Ile  Gln Gln His Tyr Arg  Thr Tyr Arg Ala Ala  Lys Leu Gln 
    2510                 2515                 2520             


Arg Glu  Asn Tyr Ile Arg Gln  Trp His Ser Ala Val  Val Ile Gln 
    2525                 2530                 2535             


Ala Ala  Tyr Lys Gly Met Lys  Ala Arg Gln Leu Leu  Arg Glu Lys 
    2540                 2545                 2550             


His Lys  Ala Ser Ile Val Ile  Gln Ser Thr Tyr Arg  Met Tyr Arg 
    2555                 2560                 2565             


Gln Tyr  Cys Phe Tyr Gln Lys  Leu Gln Trp Ala Thr  Lys Ile Ile 
    2570                 2575                 2580             


Gln Glu  Lys Tyr Arg Ala Asn  Lys Lys Lys Gln Lys  Val Phe Gln 
    2585                 2590                 2595             


His Asn  Glu Leu Lys Lys Glu  Thr Cys Val Gln Ala  Gly Phe Gln 
    2600                 2605                 2610             


Asp Met  Asn Ile Lys Lys Gln  Ile Gln Glu Gln His  Gln Ala Ala 
    2615                 2620                 2625             


Ile Ile  Ile Gln Lys His Cys  Lys Ala Phe Lys Ile  Arg Lys His 
    2630                 2635                 2640             


Tyr Leu  His Leu Arg Ala Thr  Val Val Ser Ile Gln  Arg Arg Tyr 
    2645                 2650                 2655             


Arg Lys  Leu Thr Ala Val Arg  Thr Gln Ala Val Ile  Cys Ile Gln 
    2660                 2665                 2670             


Ser Tyr  Tyr Arg Gly Phe Lys  Val Arg Lys Asp Ile  Gln Asn Met 
    2675                 2680                 2685             


His Arg  Ala Ala Thr Leu Ile  Gln Ser Phe Tyr Arg  Met His Arg 
    2690                 2695                 2700             


Ala Lys  Val Asp Tyr Glu Thr  Lys Lys Thr Ala Ile  Val Val Ile 
    2705                 2710                 2715             


Gln Asn  Tyr Tyr Arg Leu Tyr  Val Arg Val Lys Thr  Glu Arg Lys 
    2720                 2725                 2730             


Asn Phe  Leu Ala Val Gln Lys  Ser Val Arg Thr Ile  Gln Ala Ala 
    2735                 2740                 2745             


Phe Arg  Gly Met Lys Val Arg  Gln Lys Leu Lys Asn  Val Ser Glu 
    2750                 2755                 2760             


Glu Lys  Met Ala Ala Ile Val  Asn Gln Ser Ala Leu  Cys Cys Tyr 
    2765                 2770                 2775             


Arg Ser  Lys Thr Gln Tyr Glu  Ala Val Gln Ser Glu  Gly Val Met 
    2780                 2785                 2790             


Ile Gln  Glu Trp Tyr Lys Ala  Ser Gly Leu Ala Cys  Ser Gln Glu 
    2795                 2800                 2805             


Ala Glu  Tyr His Ser Gln Ser  Arg Ala Ala Val Thr  Ile Gln Lys 
    2810                 2815                 2820             


Ala Phe  Cys Arg Met Val Thr  Arg Lys Leu Glu Thr  Gln Lys Cys 
    2825                 2830                 2835             


Ala Ala  Leu Arg Ile Gln Phe  Phe Leu Gln Met Ala  Val Tyr Arg 
    2840                 2845                 2850             


Arg Arg  Phe Val Gln Gln Lys  Arg Ala Ala Ile Thr  Leu Gln His 
    2855                 2860                 2865             


Tyr Phe  Arg Thr Trp Gln Thr  Arg Lys Gln Phe Leu  Leu Tyr Arg 
    2870                 2875                 2880             


Lys Ala  Ala Val Val Leu Gln  Asn His Tyr Arg Ala  Phe Leu Ser 
    2885                 2890                 2895             


Ala Lys  His Gln Arg Gln Val  Tyr Leu Gln Ile Arg  Ser Ser Val 
    2900                 2905                 2910             


Ile Ile  Ile Gln Ala Arg Ser  Lys Gly Phe Ile Gln  Lys Arg Lys 
    2915                 2920                 2925             


Phe Gln  Glu Ile Lys Asn Ser  Thr Ile Lys Ile Gln  Ala Met Trp 
    2930                 2935                 2940             


Arg Arg  Tyr Arg Ala Lys Lys  Tyr Leu Cys Lys Val  Lys Ala Ala 
    2945                 2950                 2955             


Cys Lys  Ile Gln Ala Trp Tyr  Arg Cys Trp Arg Ala  His Lys Glu 
    2960                 2965                 2970             


Tyr Leu  Ala Ile Leu Lys Ala  Val Lys Ile Ile Gln  Gly Cys Phe 
    2975                 2980                 2985             


Tyr Thr  Lys Leu Glu Arg Thr  Arg Phe Leu Asn Val  Arg Ala Ser 
    2990                 2995                 3000             


Ala Ile  Ile Ile Gln Arg Lys  Trp Arg Ala Ile Leu  Pro Ala Lys 
    3005                 3010                 3015             


Ile Ala  His Glu His Phe Leu  Met Ile Lys Arg His  Arg Ala Ala 
    3020                 3025                 3030             


Cys Leu  Ile Gln Ala His Tyr  Arg Gly Tyr Lys Gly  Arg Gln Val 
    3035                 3040                 3045             


Phe Leu  Arg Gln Lys Ser Ala  Ala Leu Ile Ile Gln  Lys Tyr Ile 
    3050                 3055                 3060             


Arg Ala  Arg Glu Ala Gly Lys  His Glu Arg Ile Lys  Tyr Ile Glu 
    3065                 3070                 3075             


Phe Lys  Lys Ser Thr Val Ile  Leu Gln Ala Leu Val  Arg Gly Trp 
    3080                 3085                 3090             


Leu Val  Arg Lys Arg Phe Leu  Glu Gln Arg Ala Lys  Ile Arg Leu 
    3095                 3100                 3105             


Leu His  Phe Thr Ala Ala Ala  Tyr Tyr His Leu Asn  Ala Val Arg 
    3110                 3115                 3120             


Ile Gln  Arg Ala Tyr Lys Leu  Tyr Leu Ala Val Lys  Asn Ala Asn 
    3125                 3130                 3135             


Lys Gln  Val Asn Ser Val Ile  Cys Ile Gln Arg Trp  Phe Arg Ala 
    3140                 3145                 3150             


Arg Leu  Gln Glu Lys Arg Phe  Ile Gln Lys Tyr His  Ser Ile Lys 
    3155                 3160                 3165             


Lys Ile  Glu His Glu Gly Gln  Glu Cys Leu Ser Gln  Arg Asn Arg 
    3170                 3175                 3180             


Ala Ala  Ser Val Ile Gln Lys  Ala Val Arg His Phe  Leu Leu Arg 
    3185                 3190                 3195             


Lys Lys  Gln Glu Lys Phe Thr  Ser Gly Ile Ile Lys  Ile Gln Ala 
    3200                 3205                 3210             


Leu Trp  Arg Gly Tyr Ser Trp  Arg Lys Lys Asn Asp  Cys Thr Lys 
    3215                 3220                 3225             


Ile Lys  Ala Ile Arg Leu Ser  Leu Gln Val Val Asn  Arg Glu Ile 
    3230                 3235                 3240             


Arg Glu  Glu Asn Lys Leu Tyr  Lys Arg Thr Ala Leu  Ala Leu His 
    3245                 3250                 3255             


Tyr Leu  Leu Thr Tyr Lys His  Leu Ser Ala Ile Leu  Glu Ala Leu 
    3260                 3265                 3270             


Lys His  Leu Glu Val Val Thr  Arg Leu Ser Pro Leu  Cys Cys Glu 
    3275                 3280                 3285             


Asn Met  Ala Gln Ser Gly Ala  Ile Ser Lys Ile Phe  Val Leu Ile 
    3290                 3295                 3300             


Arg Ser  Cys Asn Arg Ser Ile  Pro Cys Met Glu Val  Ile Arg Tyr 
    3305                 3310                 3315             


Ala Val  Gln Val Leu Leu Asn  Val Ser Lys Tyr Glu  Lys Thr Thr 
    3320                 3325                 3330             


Ser Ala  Val Tyr Asp Val Glu  Asn Cys Ile Asp Ile  Leu Leu Glu 
    3335                 3340                 3345             


Leu Leu  Gln Ile Tyr Arg Glu  Lys Pro Gly Asn Lys  Val Ala Asp 
    3350                 3355                 3360             


Lys Gly  Gly Ser Ile Phe Thr  Lys Thr Cys Cys Leu  Leu Ala Ile 
    3365                 3370                 3375             


Leu Leu  Lys Thr Thr Asn Arg  Ala Ser Asp Val Arg  Ser Arg Ser 
    3380                 3385                 3390             


Lys Val  Val Asp Arg Ile Tyr  Ser Leu Tyr Lys Leu  Thr Ala His 
    3395                 3400                 3405             


Lys His  Lys Met Asn Thr Glu  Arg Ile Leu Tyr Lys  Gln Lys Lys 
    3410                 3415                 3420             


Asn Ser  Ser Ile Ser Ile Pro  Phe Ile Pro Glu Thr  Pro Val Arg 
    3425                 3430                 3435             


Thr Arg  Ile Val Ser Arg Leu  Lys Pro Asp Trp Val  Leu Arg Arg 
    3440                 3445                 3450             


Asp Asn  Met Glu Glu Ile Thr  Asn Pro Leu Gln Ala  Ile Gln Met 
    3455                 3460                 3465             


Val Met  Asp Thr Leu Gly Ile  Pro Tyr 
    3470                 3475         


<210>  3860
<211>  1159
<212>  PRT
<213>  homo sapiens

<400>  3860

Met Pro Val Arg Arg Gly His Val Ala Pro Gln Asn Thr Phe Leu Asp 
1               5                   10                  15      


Thr Ile Ile Arg Lys Phe Glu Gly Gln Ser Arg Lys Phe Ile Ile Ala 
            20                  25                  30          


Asn Ala Arg Val Glu Asn Cys Ala Val Ile Tyr Cys Asn Asp Gly Phe 
        35                  40                  45              


Cys Glu Leu Cys Gly Tyr Ser Arg Ala Glu Val Met Gln Arg Pro Cys 
    50                  55                  60                  


Thr Cys Asp Phe Leu His Gly Pro Arg Thr Gln Arg Arg Ala Ala Ala 
65                  70                  75                  80  


Gln Ile Ala Gln Ala Leu Leu Gly Ala Glu Glu Arg Lys Val Glu Ile 
                85                  90                  95      


Ala Phe Tyr Arg Lys Asp Gly Ser Cys Phe Leu Cys Leu Val Asp Val 
            100                 105                 110         


Val Pro Val Lys Asn Glu Asp Gly Ala Val Ile Met Phe Ile Leu Asn 
        115                 120                 125             


Phe Glu Val Val Met Glu Lys Asp Met Val Gly Ser Pro Ala His Asp 
    130                 135                 140                 


Thr Asn His Arg Gly Pro Pro Thr Ser Trp Leu Ala Pro Gly Arg Ala 
145                 150                 155                 160 


Lys Thr Phe Arg Leu Lys Leu Pro Ala Leu Leu Ala Leu Thr Ala Arg 
                165                 170                 175     


Glu Ser Ser Val Arg Ser Gly Gly Ala Gly Gly Ala Gly Ala Pro Gly 
            180                 185                 190         


Ala Val Val Val Asp Val Asp Leu Thr Pro Ala Ala Pro Ser Ser Glu 
        195                 200                 205             


Ser Leu Ala Leu Asp Glu Val Thr Ala Met Asp Asn His Val Ala Gly 
    210                 215                 220                 


Leu Gly Pro Ala Glu Glu Arg Arg Ala Leu Val Gly Pro Gly Ser Pro 
225                 230                 235                 240 


Pro Arg Ser Ala Pro Gly Gln Leu Pro Ser Pro Arg Ala His Ser Leu 
                245                 250                 255     


Asn Pro Asp Ala Ser Gly Ser Ser Cys Ser Leu Ala Arg Thr Arg Ser 
            260                 265                 270         


Arg Glu Ser Cys Ala Ser Val Arg Arg Ala Ser Ser Ala Asp Asp Ile 
        275                 280                 285             


Glu Ala Met Arg Ala Gly Val Leu Pro Pro Pro Pro Arg His Ala Ser 
    290                 295                 300                 


Thr Gly Ala Met His Pro Leu Arg Ser Gly Leu Leu Asn Ser Thr Ser 
305                 310                 315                 320 


Asp Ser Asp Leu Val Arg Tyr Arg Thr Ile Ser Lys Ile Pro Gln Ile 
                325                 330                 335     


Thr Leu Asn Phe Val Asp Leu Lys Gly Asp Pro Phe Leu Ala Ser Pro 
            340                 345                 350         


Thr Ser Asp Arg Glu Ile Ile Ala Pro Lys Ile Lys Glu Arg Thr His 
        355                 360                 365             


Asn Val Thr Glu Lys Val Thr Gln Val Leu Ser Leu Gly Ala Asp Val 
    370                 375                 380                 


Leu Pro Glu Tyr Lys Leu Gln Ala Pro Arg Ile His Arg Trp Thr Ile 
385                 390                 395                 400 


Leu His Tyr Ser Pro Phe Lys Ala Val Trp Asp Trp Leu Ile Leu Leu 
                405                 410                 415     


Leu Val Ile Tyr Thr Ala Val Phe Thr Pro Tyr Ser Ala Ala Phe Leu 
            420                 425                 430         


Leu Lys Glu Thr Glu Glu Gly Pro Pro Ala Thr Glu Cys Gly Tyr Ala 
        435                 440                 445             


Cys Gln Pro Leu Ala Val Val Asp Leu Ile Val Asp Ile Met Phe Ile 
    450                 455                 460                 


Val Asp Ile Leu Ile Asn Phe Arg Thr Thr Tyr Val Asn Ala Asn Glu 
465                 470                 475                 480 


Glu Val Val Ser His Pro Gly Arg Ile Ala Val His Tyr Phe Lys Gly 
                485                 490                 495     


Trp Phe Leu Ile Asp Met Val Ala Ala Ile Pro Phe Asp Leu Leu Ile 
            500                 505                 510         


Phe Gly Ser Gly Ser Glu Glu Leu Ile Gly Leu Leu Lys Thr Ala Arg 
        515                 520                 525             


Leu Leu Arg Leu Val Arg Val Ala Arg Lys Leu Asp Arg Tyr Ser Glu 
    530                 535                 540                 


Tyr Gly Ala Ala Val Leu Phe Leu Leu Met Cys Thr Phe Ala Leu Ile 
545                 550                 555                 560 


Ala His Trp Leu Ala Cys Ile Trp Tyr Ala Ile Gly Asn Met Glu Gln 
                565                 570                 575     


Pro His Met Asp Ser Arg Ile Gly Trp Leu His Asn Leu Gly Asp Gln 
            580                 585                 590         


Ile Gly Lys Pro Tyr Asn Ser Ser Gly Leu Gly Gly Pro Ser Ile Lys 
        595                 600                 605             


Asp Lys Tyr Val Thr Ala Leu Tyr Phe Thr Phe Ser Ser Leu Thr Ser 
    610                 615                 620                 


Val Gly Phe Gly Asn Val Ser Pro Asn Thr Asn Ser Glu Lys Ile Phe 
625                 630                 635                 640 


Ser Ile Cys Val Met Leu Ile Gly Ser Leu Met Tyr Ala Ser Ile Phe 
                645                 650                 655     


Gly Asn Val Ser Ala Ile Ile Gln Arg Leu Tyr Ser Gly Thr Ala Arg 
            660                 665                 670         


Tyr His Thr Gln Met Leu Arg Val Arg Glu Phe Ile Arg Phe His Gln 
        675                 680                 685             


Ile Pro Asn Pro Leu Arg Gln Arg Leu Glu Glu Tyr Phe Gln His Ala 
    690                 695                 700                 


Trp Ser Tyr Thr Asn Gly Ile Asp Met Asn Ala Val Leu Lys Gly Phe 
705                 710                 715                 720 


Pro Glu Cys Leu Gln Ala Asp Ile Cys Leu His Leu Asn Arg Ser Leu 
                725                 730                 735     


Leu Gln His Cys Lys Pro Phe Arg Gly Ala Thr Lys Gly Cys Leu Arg 
            740                 745                 750         


Ala Leu Ala Met Lys Phe Lys Thr Thr His Ala Pro Pro Gly Asp Thr 
        755                 760                 765             


Leu Val His Ala Gly Asp Leu Leu Thr Ala Leu Tyr Phe Ile Ser Arg 
    770                 775                 780                 


Gly Ser Ile Glu Ile Leu Arg Gly Asp Val Val Val Ala Ile Leu Gly 
785                 790                 795                 800 


Lys Asn Asp Ile Phe Gly Glu Pro Leu Asn Leu Tyr Ala Arg Pro Gly 
                805                 810                 815     


Lys Ser Asn Gly Asp Val Arg Ala Leu Thr Tyr Cys Asp Leu His Lys 
            820                 825                 830         


Ile His Arg Asp Asp Leu Leu Glu Val Leu Asp Met Tyr Pro Glu Phe 
        835                 840                 845             


Ser Asp His Phe Trp Ser Ser Leu Glu Ile Thr Phe Asn Leu Arg Asp 
    850                 855                 860                 


Thr Asn Met Ile Pro Gly Ser Pro Gly Ser Thr Glu Leu Glu Gly Gly 
865                 870                 875                 880 


Phe Ser Arg Gln Arg Lys Arg Lys Leu Ser Phe Arg Arg Arg Thr Asp 
                885                 890                 895     


Lys Asp Thr Glu Gln Pro Gly Glu Val Ser Ala Leu Gly Pro Gly Arg 
            900                 905                 910         


Ala Gly Ala Gly Pro Ser Ser Arg Gly Arg Pro Gly Gly Pro Trp Gly 
        915                 920                 925             


Glu Ser Pro Ser Ser Gly Pro Ser Ser Pro Glu Ser Ser Glu Asp Glu 
    930                 935                 940                 


Gly Pro Gly Arg Ser Ser Ser Pro Leu Arg Leu Val Pro Phe Ser Ser 
945                 950                 955                 960 


Pro Arg Pro Pro Gly Glu Pro Pro Gly Gly Glu Pro Leu Met Glu Asp 
                965                 970                 975     


Cys Glu Lys Ser Ser Asp Thr Cys Asn Pro Leu Ser Gly Ala Phe Ser 
            980                 985                 990         


Gly Val Ser Asn Ile Phe Ser Phe  Trp Gly Asp Ser Arg  Gly Arg Gln 
        995                 1000                 1005             


Tyr Gln  Glu Leu Pro Arg Cys  Pro Ala Pro Thr Pro  Ser Leu Leu 
    1010                 1015                 1020             


Asn Ile  Pro Leu Ser Ser Pro  Gly Arg Arg Pro Arg  Gly Asp Val 
    1025                 1030                 1035             


Glu Ser  Arg Leu Asp Ala Leu  Gln Arg Gln Leu Asn  Arg Leu Glu 
    1040                 1045                 1050             


Thr Arg  Leu Ser Ala Asp Met  Ala Thr Val Leu Gln  Leu Leu Gln 
    1055                 1060                 1065             


Arg Gln  Met Thr Leu Val Pro  Pro Ala Tyr Ser Ala  Val Thr Thr 
    1070                 1075                 1080             


Pro Gly  Pro Gly Pro Thr Ser  Thr Ser Pro Leu Leu  Pro Val Ser 
    1085                 1090                 1095             


Pro Leu  Pro Thr Leu Thr Leu  Asp Ser Leu Ser Gln  Val Ser Gln 
    1100                 1105                 1110             


Phe Met  Ala Cys Glu Glu Leu  Pro Pro Gly Ala Pro  Glu Leu Pro 
    1115                 1120                 1125             


Gln Glu  Gly Pro Thr Arg Arg  Leu Ser Leu Pro Gly  Gln Leu Gly 
    1130                 1135                 1140             


Ala Leu  Thr Ser Gln Pro Leu  His Arg His Gly Ser  Asp Pro Gly 
    1145                 1150                 1155             


Ser 
    


<210>  3861
<211>  806
<212>  PRT
<213>  homo sapiens

<400>  3861

Met Gly Ala Pro Ala Cys Ala Leu Ala Leu Cys Val Ala Val Ala Ile 
1               5                   10                  15      


Val Ala Gly Ala Ser Ser Glu Ser Leu Gly Thr Glu Gln Arg Val Val 
            20                  25                  30          


Gly Arg Ala Ala Glu Val Pro Gly Pro Glu Pro Gly Gln Gln Glu Gln 
        35                  40                  45              


Leu Val Phe Gly Ser Gly Asp Ala Val Glu Leu Ser Cys Pro Pro Pro 
    50                  55                  60                  


Gly Gly Gly Pro Met Gly Pro Thr Val Trp Val Lys Asp Gly Thr Gly 
65                  70                  75                  80  


Leu Val Pro Ser Glu Arg Val Leu Val Gly Pro Gln Arg Leu Gln Val 
                85                  90                  95      


Leu Asn Ala Ser His Glu Asp Ser Gly Ala Tyr Ser Cys Arg Gln Arg 
            100                 105                 110         


Leu Thr Gln Arg Val Leu Cys His Phe Ser Val Arg Val Thr Asp Ala 
        115                 120                 125             


Pro Ser Ser Gly Asp Asp Glu Asp Gly Glu Asp Glu Ala Glu Asp Thr 
    130                 135                 140                 


Gly Val Asp Thr Gly Ala Pro Tyr Trp Thr Arg Pro Glu Arg Met Asp 
145                 150                 155                 160 


Lys Lys Leu Leu Ala Val Pro Ala Ala Asn Thr Val Arg Phe Arg Cys 
                165                 170                 175     


Pro Ala Ala Gly Asn Pro Thr Pro Ser Ile Ser Trp Leu Lys Asn Gly 
            180                 185                 190         


Arg Glu Phe Arg Gly Glu His Arg Ile Gly Gly Ile Lys Leu Arg His 
        195                 200                 205             


Gln Gln Trp Ser Leu Val Met Glu Ser Val Val Pro Ser Asp Arg Gly 
    210                 215                 220                 


Asn Tyr Thr Cys Val Val Glu Asn Lys Phe Gly Ser Ile Arg Gln Thr 
225                 230                 235                 240 


Tyr Thr Leu Asp Val Leu Glu Arg Ser Pro His Arg Pro Ile Leu Gln 
                245                 250                 255     


Ala Gly Leu Pro Ala Asn Gln Thr Ala Val Leu Gly Ser Asp Val Glu 
            260                 265                 270         


Phe His Cys Lys Val Tyr Ser Asp Ala Gln Pro His Ile Gln Trp Leu 
        275                 280                 285             


Lys His Val Glu Val Asn Gly Ser Lys Val Gly Pro Asp Gly Thr Pro 
    290                 295                 300                 


Tyr Val Thr Val Leu Lys Thr Ala Gly Ala Asn Thr Thr Asp Lys Glu 
305                 310                 315                 320 


Leu Glu Val Leu Ser Leu His Asn Val Thr Phe Glu Asp Ala Gly Glu 
                325                 330                 335     


Tyr Thr Cys Leu Ala Gly Asn Ser Ile Gly Phe Ser His His Ser Ala 
            340                 345                 350         


Trp Leu Val Val Leu Pro Ala Glu Glu Glu Leu Val Glu Ala Asp Glu 
        355                 360                 365             


Ala Gly Ser Val Tyr Ala Gly Ile Leu Ser Tyr Gly Val Gly Phe Phe 
    370                 375                 380                 


Leu Phe Ile Leu Val Val Ala Ala Val Thr Leu Cys Arg Leu Arg Ser 
385                 390                 395                 400 


Pro Pro Lys Lys Gly Leu Gly Ser Pro Thr Val His Lys Ile Ser Arg 
                405                 410                 415     


Phe Pro Leu Lys Arg Gln Val Ser Leu Glu Ser Asn Ala Ser Met Ser 
            420                 425                 430         


Ser Asn Thr Pro Leu Val Arg Ile Ala Arg Leu Ser Ser Gly Glu Gly 
        435                 440                 445             


Pro Thr Leu Ala Asn Val Ser Glu Leu Glu Leu Pro Ala Asp Pro Lys 
    450                 455                 460                 


Trp Glu Leu Ser Arg Ala Arg Leu Thr Leu Gly Lys Pro Leu Gly Glu 
465                 470                 475                 480 


Gly Cys Phe Gly Gln Val Val Met Ala Glu Ala Ile Gly Ile Asp Lys 
                485                 490                 495     


Asp Arg Ala Ala Lys Pro Val Thr Val Ala Val Lys Met Leu Lys Asp 
            500                 505                 510         


Asp Ala Thr Asp Lys Asp Leu Ser Asp Leu Val Ser Glu Met Glu Met 
        515                 520                 525             


Met Lys Met Ile Gly Lys His Lys Asn Ile Ile Asn Leu Leu Gly Ala 
    530                 535                 540                 


Cys Thr Gln Gly Gly Pro Leu Tyr Val Leu Val Glu Tyr Ala Ala Lys 
545                 550                 555                 560 


Gly Asn Leu Arg Glu Phe Leu Arg Ala Arg Arg Pro Pro Gly Leu Asp 
                565                 570                 575     


Tyr Ser Phe Asp Thr Cys Lys Pro Pro Glu Glu Gln Leu Thr Phe Lys 
            580                 585                 590         


Asp Leu Val Ser Cys Ala Tyr Gln Val Ala Arg Gly Met Glu Tyr Leu 
        595                 600                 605             


Ala Ser Gln Lys Cys Ile His Arg Asp Leu Ala Ala Arg Asn Val Leu 
    610                 615                 620                 


Val Thr Glu Asp Asn Val Met Lys Ile Ala Asp Phe Gly Leu Ala Arg 
625                 630                 635                 640 


Asp Val His Asn Leu Asp Tyr Tyr Lys Lys Thr Thr Asn Gly Arg Leu 
                645                 650                 655     


Pro Val Lys Trp Met Ala Pro Glu Ala Leu Phe Asp Arg Val Tyr Thr 
            660                 665                 670         


His Gln Ser Asp Val Trp Ser Phe Gly Val Leu Leu Trp Glu Ile Phe 
        675                 680                 685             


Thr Leu Gly Gly Ser Pro Tyr Pro Gly Ile Pro Val Glu Glu Leu Phe 
    690                 695                 700                 


Lys Leu Leu Lys Glu Gly His Arg Met Asp Lys Pro Ala Asn Cys Thr 
705                 710                 715                 720 


His Asp Leu Tyr Met Ile Met Arg Glu Cys Trp His Ala Ala Pro Ser 
                725                 730                 735     


Gln Arg Pro Thr Phe Lys Gln Leu Val Glu Asp Leu Asp Arg Val Leu 
            740                 745                 750         


Thr Val Thr Ser Thr Asp Glu Tyr Leu Asp Leu Ser Ala Pro Phe Glu 
        755                 760                 765             


Gln Tyr Ser Pro Gly Gly Gln Asp Thr Pro Ser Ser Ser Ser Ser Gly 
    770                 775                 780                 


Asp Asp Ser Val Phe Ala His Asp Leu Leu Pro Pro Ala Pro Pro Ser 
785                 790                 795                 800 


Ser Gly Gly Ser Arg Thr 
                805     


<210>  3862
<211>  4981
<212>  PRT
<213>  homo sapiens

<400>  3862

Met Asp Leu Ala Pro Asp Arg Ala Thr Gly Arg Pro Trp Leu Pro Leu 
1               5                   10                  15      


His Thr Leu Ser Val Ser Gln Leu Leu Arg Val Phe Trp Leu Leu Ser 
            20                  25                  30          


Leu Leu Pro Gly Gln Ala Trp Val His Gly Ala Glu Pro Arg Gln Val 
        35                  40                  45              


Phe Gln Val Leu Glu Glu Gln Pro Pro Gly Thr Leu Val Gly Thr Ile 
    50                  55                  60                  


Gln Thr Arg Pro Gly Phe Thr Tyr Arg Leu Ser Glu Ser His Ala Leu 
65                  70                  75                  80  


Phe Ala Ile Asn Ser Ser Thr Gly Ala Leu Tyr Thr Thr Ser Thr Ile 
                85                  90                  95      


Asp Arg Glu Ser Leu Pro Ser Asp Val Ile Asn Leu Val Val Leu Ser 
            100                 105                 110         


Ser Ala Pro Thr Tyr Pro Thr Glu Val Arg Val Leu Val Arg Asp Leu 
        115                 120                 125             


Asn Asp Asn Ala Pro Val Phe Pro Asp Pro Ser Ile Val Val Thr Phe 
    130                 135                 140                 


Lys Glu Asp Ser Ser Ser Gly Arg Gln Val Ile Leu Asp Thr Ala Thr 
145                 150                 155                 160 


Asp Ser Asp Ile Gly Ser Asn Gly Val Asp His Arg Ser Tyr Arg Ile 
                165                 170                 175     


Ile Arg Gly Asn Glu Ala Gly Arg Phe Arg Leu Asp Ile Thr Leu Asn 
            180                 185                 190         


Pro Ser Gly Glu Gly Ala Phe Leu His Leu Val Ser Lys Gly Gly Leu 
        195                 200                 205             


Asp Arg Glu Val Thr Pro Gln Tyr Gln Leu Leu Val Glu Val Glu Asp 
    210                 215                 220                 


Lys Gly Glu Pro Lys Arg Arg Gly Tyr Leu Gln Val Asn Val Thr Val 
225                 230                 235                 240 


Gln Asp Ile Asn Asp Asn Pro Pro Val Phe Gly Ser Ser His Tyr Gln 
                245                 250                 255     


Ala Gly Val Pro Glu Asp Ala Val Val Gly Ser Ser Val Leu Gln Val 
            260                 265                 270         


Ala Ala Ala Asp Ala Asp Glu Gly Thr Asn Ala Asp Ile Arg Tyr Arg 
        275                 280                 285             


Leu Gln Asp Glu Gly Thr Pro Phe Gln Met Asp Pro Glu Thr Gly Leu 
    290                 295                 300                 


Ile Thr Val Arg Glu Pro Leu Asp Phe Glu Ala Arg Arg Gln Tyr Ser 
305                 310                 315                 320 


Leu Thr Val Gln Ala Met Asp Arg Gly Val Pro Ser Leu Thr Gly Arg 
                325                 330                 335     


Ala Glu Ala Leu Ile Gln Leu Leu Asp Val Asn Asp Asn Asp Pro Val 
            340                 345                 350         


Val Lys Phe Arg Tyr Phe Pro Ala Thr Ser Arg Tyr Ala Ser Val Asp 
        355                 360                 365             


Glu Asn Ala Gln Val Gly Thr Val Val Ala Leu Leu Thr Val Thr Asp 
    370                 375                 380                 


Ala Asp Ser Pro Ala Ala Asn Gly Asn Ile Ser Val Gln Ile Leu Gly 
385                 390                 395                 400 


Gly Asn Glu Gln Arg His Phe Glu Val Gln Ser Ser Lys Val Pro Asn 
                405                 410                 415     


Leu Ser Leu Ile Lys Val Ala Ser Ala Leu Asp Arg Glu Arg Ile Pro 
            420                 425                 430         


Ser Tyr Asn Leu Thr Val Ser Val Ser Asp Asn Tyr Gly Ala Pro Pro 
        435                 440                 445             


Gly Ala Ala Val Gln Ala Arg Ser Ser Val Ala Ser Leu Val Ile Phe 
    450                 455                 460                 


Val Asn Asp Ile Asn Asp His Pro Pro Val Phe Ser Gln Gln Val Tyr 
465                 470                 475                 480 


Arg Val Asn Leu Ser Glu Glu Ala Pro Pro Gly Ser Tyr Val Ser Gly 
                485                 490                 495     


Ile Ser Ala Thr Asp Gly Asp Ser Gly Leu Asn Ala Asn Leu Arg Tyr 
            500                 505                 510         


Ser Ile Val Ser Gly Asn Gly Leu Gly Trp Phe His Ile Ser Glu His 
        515                 520                 525             


Ser Gly Leu Val Thr Thr Gly Ser Ser Gly Gly Leu Asp Arg Glu Leu 
    530                 535                 540                 


Ala Ser Gln Ile Val Leu Asn Ile Ser Ala Arg Asp Gln Gly Val His 
545                 550                 555                 560 


Pro Lys Val Ser Tyr Ala Gln Leu Val Val Thr Leu Leu Asp Val Asn 
                565                 570                 575     


Asp Glu Lys Pro Val Phe Ser Gln Pro Glu Gly Tyr Asp Val Ser Val 
            580                 585                 590         


Val Glu Asn Ala Pro Thr Gly Thr Glu Leu Leu Met Leu Arg Ala Thr 
        595                 600                 605             


Asp Gly Asp Leu Gly Asp Asn Gly Thr Val Arg Phe Ser Leu Gln Glu 
    610                 615                 620                 


Ala Glu Thr Asp Arg Arg Ser Phe Arg Leu Asp Pro Val Ser Gly Arg 
625                 630                 635                 640 


Leu Ser Thr Ile Ser Ser Leu Asp Arg Glu Glu Gln Ala Phe Tyr Ser 
                645                 650                 655     


Leu Leu Val Leu Ala Thr Asp Leu Gly Ser Pro Pro Gln Ser Ser Met 
            660                 665                 670         


Ala Arg Ile Asn Val Ser Leu Leu Asp Ile Asn Asp Asn Ser Pro Val 
        675                 680                 685             


Phe Tyr Pro Val Gln Tyr Phe Ala His Ile Lys Glu Asn Glu Pro Gly 
    690                 695                 700                 


Gly Ser Tyr Ile Thr Thr Val Ser Ala Thr Asp Pro Asp Leu Gly Thr 
705                 710                 715                 720 


Asn Gly Thr Val Lys Tyr Ser Ile Ser Ala Gly Asp Arg Ser Arg Phe 
                725                 730                 735     


Gln Val Asn Ala Gln Ser Gly Val Ile Ser Thr Arg Met Ala Leu Asp 
            740                 745                 750         


Arg Glu Glu Lys Thr Ala Tyr Gln Leu Gln Ile Val Ala Thr Asp Gly 
        755                 760                 765             


Gly Asn Leu Gln Ser Pro Asn Gln Ala Ile Val Thr Ile Thr Val Leu 
    770                 775                 780                 


Asp Thr Gln Asp Asn Pro Pro Val Phe Ser Gln Val Ala Tyr Ser Phe 
785                 790                 795                 800 


Val Val Phe Glu Asn Val Ala Leu Gly Tyr His Val Gly Ser Val Ser 
                805                 810                 815     


Ala Ser Thr Met Asp Leu Asn Ser Asn Ile Ser Tyr Leu Ile Thr Thr 
            820                 825                 830         


Gly Asp Gln Lys Gly Met Phe Ala Ile Asn Gln Val Thr Gly Gln Leu 
        835                 840                 845             


Thr Thr Ala Asn Val Ile Asp Arg Glu Glu Gln Ser Phe Tyr Gln Leu 
    850                 855                 860                 


Lys Val Val Ala Ser Gly Gly Thr Val Thr Gly Asp Thr Met Val Asn 
865                 870                 875                 880 


Ile Thr Val Lys Asp Leu Asn Asp Asn Ser Pro His Phe Leu Gln Ala 
                885                 890                 895     


Ile Glu Ser Val Asn Val Val Glu Asn Trp Gln Ala Gly His Ser Ile 
            900                 905                 910         


Phe Gln Ala Lys Ala Val Asp Pro Asp Glu Gly Val Asn Gly Met Val 
        915                 920                 925             


Leu Tyr Ser Leu Lys Gln Asn Pro Lys Asn Leu Phe Ala Ile Asn Glu 
    930                 935                 940                 


Lys Asn Gly Thr Ile Ser Leu Leu Gly Pro Leu Asp Val His Ala Gly 
945                 950                 955                 960 


Ser Tyr Gln Ile Glu Ile Leu Ala Ser Asp Met Gly Val Pro Gln Leu 
                965                 970                 975     


Ser Ser Ser Val Ile Leu Thr Val Tyr Val His Asp Val Asn Asp Asn 
            980                 985                 990         


Ser Pro Val Phe Asp Gln Leu Ser  Tyr Glu Val Thr Leu  Ser Glu Ser 
        995                 1000                 1005             


Glu Pro  Val Asn Ser Arg Phe  Phe Lys Val Gln Ala  Ser Asp Lys 
    1010                 1015                 1020             


Asp Ser  Gly Ala Asn Gly Glu  Ile Ala Tyr Thr Ile  Ala Glu Gly 
    1025                 1030                 1035             


Asn Thr  Gly Asp Ala Phe Gly  Ile Phe Pro Asp Gly  Gln Leu Tyr 
    1040                 1045                 1050             


Ile Lys  Ser Glu Leu Asp Arg  Glu Leu Gln Asp Arg  Tyr Val Leu 
    1055                 1060                 1065             


Met Val  Val Ala Ser Asp Arg  Ala Val Glu Pro Leu  Ser Ala Thr 
    1070                 1075                 1080             


Val Asn  Val Thr Val Ile Leu  Glu Asp Val Asn Asp  Asn Arg Pro 
    1085                 1090                 1095             


Leu Phe  Asn Ser Thr Asn Tyr  Thr Phe Tyr Phe Glu  Glu Glu Gln 
    1100                 1105                 1110             


Arg Ala  Gly Ser Phe Val Gly  Lys Val Ser Ala Val  Asp Lys Asp 
    1115                 1120                 1125             


Phe Gly  Pro Asn Gly Glu Val  Arg Tyr Ser Phe Glu  Met Val Gln 
    1130                 1135                 1140             


Pro Asp  Phe Glu Leu His Ala  Ile Ser Gly Glu Ile  Thr Asn Thr 
    1145                 1150                 1155             


His Gln  Phe Asp Arg Glu Ser  Leu Met Arg Arg Arg  Gly Thr Ala 
    1160                 1165                 1170             


Val Phe  Ser Phe Thr Val Ile  Ala Thr Asp Gln Gly  Ile Pro Gln 
    1175                 1180                 1185             


Pro Leu  Lys Asp Gln Ala Thr  Val His Val Tyr Met  Lys Asp Ile 
    1190                 1195                 1200             


Asn Asp  Asn Ala Pro Lys Phe  Leu Lys Asp Phe Tyr  Gln Ala Thr 
    1205                 1210                 1215             


Ile Ser  Glu Ser Ala Ala Asn  Leu Thr Gln Val Leu  Arg Val Ser 
    1220                 1225                 1230             


Ala Ser  Asp Val Asp Glu Gly  Asn Asn Gly Leu Ile  His Tyr Ser 
    1235                 1240                 1245             


Ile Ile  Lys Gly Asn Glu Glu  Arg Gln Phe Ala Ile  Asp Ser Thr 
    1250                 1255                 1260             


Ser Gly  Gln Val Thr Leu Ile  Gly Lys Leu Asp Tyr  Glu Ala Thr 
    1265                 1270                 1275             


Pro Ala  Tyr Ser Leu Val Ile  Gln Ala Val Asp Ser  Gly Thr Ile 
    1280                 1285                 1290             


Pro Leu  Asn Ser Thr Cys Thr  Leu Asn Ile Asp Ile  Leu Asp Glu 
    1295                 1300                 1305             


Asn Asp  Asn Thr Pro Ser Phe  Pro Lys Ser Thr Leu  Phe Val Asp 
    1310                 1315                 1320             


Val Leu  Glu Asn Met Arg Ile  Gly Glu Leu Val Ser  Ser Val Thr 
    1325                 1330                 1335             


Ala Thr  Asp Ser Asp Ser Gly  Asp Asn Ala Asp Leu  Tyr Tyr Ser 
    1340                 1345                 1350             


Ile Thr  Gly Thr Asn Asn His  Gly Thr Phe Ser Ile  Ser Pro Asn 
    1355                 1360                 1365             


Thr Gly  Ser Ile Phe Leu Ala  Lys Lys Leu Asp Phe  Glu Thr Gln 
    1370                 1375                 1380             


Ser Leu  Tyr Lys Leu Asn Ile  Thr Ala Lys Asp Gln  Gly Arg Pro 
    1385                 1390                 1395             


Pro Arg  Ser Ser Thr Met Ser  Val Val Ile His Val  Arg Asp Phe 
    1400                 1405                 1410             


Asn Asp  Asn Pro Pro Ser Phe  Pro Pro Gly Asp Ile  Phe Lys Ser 
    1415                 1420                 1425             


Ile Val  Glu Asn Ile Pro Ile  Gly Thr Ser Val Ile  Ser Val Thr 
    1430                 1435                 1440             


Ala His  Asp Pro Asp Ala Asp  Ile Asn Gly Gln Leu  Ser Tyr Thr 
    1445                 1450                 1455             


Ile Ile  Gln Gln Met Pro Arg  Gly Asn His Phe Thr  Ile Asp Glu 
    1460                 1465                 1470             


Val Lys  Gly Thr Ile Tyr Thr  Asn Ala Glu Ile Asp  Arg Glu Phe 
    1475                 1480                 1485             


Ala Asn  Leu Phe Glu Leu Thr  Val Lys Ala Asn Asp  Gln Ala Val 
    1490                 1495                 1500             


Pro Ile  Glu Thr Arg Arg Tyr  Ala Leu Lys Asn Val  Thr Ile Leu 
    1505                 1510                 1515             


Val Thr  Asp Leu Asn Asp Asn  Val Pro Met Phe Ile  Ser Gln Asn 
    1520                 1525                 1530             


Ala Leu  Ala Ala Asp Pro Ser  Ala Val Ile Gly Ser  Val Leu Thr 
    1535                 1540                 1545             


Thr Ile  Met Ala Ala Asp Pro  Asp Glu Gly Ala Asn  Gly Glu Ile 
    1550                 1555                 1560             


Glu Tyr  Glu Ile Ile Asn Gly  Asp Thr Asp Thr Phe  Ile Val Asp 
    1565                 1570                 1575             


Arg Tyr  Ser Gly Asp Leu Arg  Val Ala Ser Ala Leu  Val Pro Ser 
    1580                 1585                 1590             


Gln Leu  Ile Tyr Asn Leu Ile  Val Ser Ala Thr Asp  Leu Gly Pro 
    1595                 1600                 1605             


Glu Arg  Arg Lys Ser Thr Thr  Glu Leu Thr Ile Ile  Leu Gln Gly 
    1610                 1615                 1620             


Leu Asp  Gly Pro Val Phe Thr  Gln Pro Lys Tyr Ile  Thr Ile Leu 
    1625                 1630                 1635             


Lys Glu  Gly Glu Pro Ile Gly  Thr Asn Val Ile Ser  Ile Glu Ala 
    1640                 1645                 1650             


Ala Ser  Pro Arg Gly Ser Glu  Ala Pro Val Glu Tyr  Tyr Ile Val 
    1655                 1660                 1665             


Ser Val  Arg Cys Glu Glu Lys  Thr Val Gly Arg Leu  Phe Thr Ile 
    1670                 1675                 1680             


Gly Arg  His Thr Gly Ile Ile  Gln Thr Ala Ala Ile  Leu Asp Arg 
    1685                 1690                 1695             


Glu Gln  Gly Ala Cys Leu Tyr  Leu Val Asp Val Tyr  Ala Ile Glu 
    1700                 1705                 1710             


Lys Ser  Thr Ala Phe Pro Arg  Thr Gln Arg Ala Glu  Val Glu Ile 
    1715                 1720                 1725             


Thr Leu  Gln Asp Ile Asn Asp  Asn Pro Pro Val Phe  Pro Thr Asp 
    1730                 1735                 1740             


Met Leu  Asp Leu Thr Val Glu  Glu Asn Ile Gly Asp  Gly Ser Lys 
    1745                 1750                 1755             


Ile Met  Gln Leu Thr Ala Met  Asp Ala Asp Glu Gly  Ala Asn Ala 
    1760                 1765                 1770             


Leu Val  Thr Tyr Thr Ile Ile  Ser Gly Ala Asp Asp  Ser Phe Arg 
    1775                 1780                 1785             


Ile Asp  Pro Glu Ser Gly Asp  Leu Ile Ala Thr Arg  Arg Leu Asp 
    1790                 1795                 1800             


Arg Glu  Arg Arg Ser Lys Tyr  Ser Leu Leu Val Arg  Ala Asp Asp 
    1805                 1810                 1815             


Gly Leu  Gln Ser Ser Asp Met  Arg Ile Asn Ile Thr  Val Ser Asp 
    1820                 1825                 1830             


Val Asn  Asp His Thr Pro Lys  Phe Ser Arg Pro Val  Tyr Ser Phe 
    1835                 1840                 1845             


Asp Ile  Pro Glu Asp Thr Ile  Pro Gly Ser Leu Val  Ala Ala Ile 
    1850                 1855                 1860             


Leu Ala  Thr Asp Asp Asp Ser  Gly Val Asn Gly Glu  Ile Thr Tyr 
    1865                 1870                 1875             


Ile Val  Asn Glu Asp Asp Glu  Asp Gly Ile Phe Phe  Leu Asn Pro 
    1880                 1885                 1890             


Ile Thr  Gly Val Phe Asn Leu  Thr Arg Leu Leu Asp  Tyr Glu Val 
    1895                 1900                 1905             


Gln Gln  Tyr Tyr Ile Leu Thr  Val Arg Ala Glu Asp  Gly Gly Gly 
    1910                 1915                 1920             


Gln Phe  Thr Thr Ile Arg Val  Tyr Phe Asn Ile Leu  Asp Val Asn 
    1925                 1930                 1935             


Asp Asn  Pro Pro Ile Phe Ser  Leu Asn Ser Tyr Ser  Thr Ser Leu 
    1940                 1945                 1950             


Met Glu  Asn Leu Pro Val Gly  Ser Thr Val Leu Val  Phe Asn Val 
    1955                 1960                 1965             


Thr Asp  Ala Asp Asp Gly Ile  Asn Ser Gln Leu Thr  Tyr Ser Ile 
    1970                 1975                 1980             


Ala Ser  Gly Asp Ser Leu Gly  Gln Phe Thr Val Asp  Lys Asn Gly 
    1985                 1990                 1995             


Val Leu  Lys Val Leu Lys Ala  Leu Asp Arg Glu Ser  Gln Ser Phe 
    2000                 2005                 2010             


Tyr Asn  Leu Val Val Gln Val  His Asp Leu Pro Gln  Ile Pro Ala 
    2015                 2020                 2025             


Ser Arg  Phe Thr Ser Thr Ala  Gln Val Ser Ile Ile  Leu Leu Asp 
    2030                 2035                 2040             


Val Asn  Asp Asn Pro Pro Thr  Phe Leu Ser Pro Lys  Leu Thr Tyr 
    2045                 2050                 2055             


Ile Pro  Glu Asn Thr Pro Ile  Asp Thr Val Val Phe  Lys Ala Gln 
    2060                 2065                 2070             


Ala Thr  Asp Pro Asp Ser Gly  Pro Asn Ser Tyr Ile  Glu Tyr Thr 
    2075                 2080                 2085             


Leu Leu  Asn Pro Leu Gly Asn  Lys Phe Ser Ile Gly  Thr Ile Asp 
    2090                 2095                 2100             


Gly Glu  Val Arg Leu Thr Gly  Glu Leu Asp Arg Glu  Glu Val Ser 
    2105                 2110                 2115             


Asn Tyr  Thr Leu Thr Val Val  Ala Thr Asp Lys Gly  Gln Pro Ser 
    2120                 2125                 2130             


Leu Ser  Ser Ser Thr Glu Val  Val Val Met Val Leu  Asp Ile Asn 
    2135                 2140                 2145             


Asp Asn  Asn Pro Ile Phe Ala  Gln Ala Leu Tyr Lys  Val Glu Ile 
    2150                 2155                 2160             


Asn Glu  Asn Thr Leu Thr Gly  Thr Asp Ile Ile Gln  Val Phe Ala 
    2165                 2170                 2175             


Ala Asp  Gly Asp Glu Gly Thr  Asn Gly Gln Val Arg  Tyr Gly Ile 
    2180                 2185                 2190             


Val Asn  Gly Asn Thr Asn Gln  Glu Phe Arg Ile Asp  Ser Val Thr 
    2195                 2200                 2205             


Gly Ala  Ile Thr Val Ala Lys  Pro Leu Asp Arg Glu  Lys Thr Pro 
    2210                 2215                 2220             


Thr Tyr  His Leu Thr Val Gln  Ala Thr Asp Arg Gly  Ser Thr Pro 
    2225                 2230                 2235             


Arg Thr  Asp Thr Ser Thr Val  Ser Ile Val Leu Leu  Asp Ile Asn 
    2240                 2245                 2250             


Asp Phe  Val Pro Val Phe Glu  Leu Ser Pro Tyr Ser  Val Asn Val 
    2255                 2260                 2265             


Pro Glu  Asn Leu Gly Thr Leu  Pro Arg Thr Ile Leu  Gln Val Val 
    2270                 2275                 2280             


Ala Arg  Asp Asp Asp Arg Gly  Ser Asn Ser Lys Leu  Ser Tyr Val 
    2285                 2290                 2295             


Leu Phe  Gly Gly Asn Glu Asp  Asn Ala Phe Thr Leu  Ser Ala Ser 
    2300                 2305                 2310             


Gly Glu  Leu Gly Val Thr Gln  Ser Leu Asp Arg Glu  Thr Lys Glu 
    2315                 2320                 2325             


Arg Phe  Val Leu Met Ile Thr  Ala Thr Asp Ser Gly  Ser Pro Ala 
    2330                 2335                 2340             


Leu Thr  Gly Thr Gly Thr Ile  Asn Val Ile Val Asp  Asp Val Asn 
    2345                 2350                 2355             


Asp Asn  Val Pro Thr Phe Ala  Ser Lys Ala Tyr Phe  Thr Thr Ile 
    2360                 2365                 2370             


Pro Glu  Asp Ala Pro Thr Gly  Thr Asp Val Leu Leu  Val Asn Ala 
    2375                 2380                 2385             


Ser Asp  Ala Asp Ala Ser Lys  Asn Ala Val Ile Arg  Ile Ile Gly 
    2390                 2395                 2400             


Gly Asn  Ser Gln Phe Thr Ile  Asn Pro Ser Thr Gly  Gln Ile Ile 
    2405                 2410                 2415             


Thr Ser  Ala Leu Leu Asp Arg  Glu Thr Lys Asp Asn  Tyr Thr Leu 
    2420                 2425                 2430             


Val Val  Val Cys Ser Asp Ala  Gly Ser Pro Glu Pro  Leu Ser Ser 
    2435                 2440                 2445             


Ser Thr  Ser Val Leu Val Thr  Val Thr Asp Val Asn  Asp Asn Pro 
    2450                 2455                 2460             


Pro Arg  Phe Gln His His Pro  Tyr Val Thr His Ile  Pro Ser Pro 
    2465                 2470                 2475             


Thr Leu  Pro Gly Ser Phe Val  Phe Ala Val Thr Val  Thr Asp Ala 
    2480                 2485                 2490             


Asp Ile  Gly Pro Asn Ser Glu  Leu His Tyr Ser Leu  Ser Gly Arg 
    2495                 2500                 2505             


Asn Ser  Glu Lys Phe His Ile  Asp Pro Leu Arg Gly  Ala Ile Met 
    2510                 2515                 2520             


Ala Ala  Gly Pro Leu Asn Gly  Ala Ser Glu Val Thr  Phe Ser Val 
    2525                 2530                 2535             


His Val  Lys Asp Gly Gly Ser  Phe Pro Lys Thr Asp  Ser Thr Thr 
    2540                 2545                 2550             


Val Thr  Val Arg Phe Val Asn  Lys Ala Asp Phe Pro  Lys Val Arg 
    2555                 2560                 2565             


Ala Lys  Glu Gln Thr Phe Met  Phe Pro Glu Asn Gln  Pro Val Ser 
    2570                 2575                 2580             


Ser Leu  Val Thr Thr Ile Thr  Gly Ser Ser Leu Arg  Gly Glu Pro 
    2585                 2590                 2595             


Met Ser  Tyr Tyr Ile Ala Ser  Gly Asn Leu Gly Asn  Thr Phe Gln 
    2600                 2605                 2610             


Ile Asp  Gln Leu Thr Gly Gln  Val Ser Ile Ser Gln  Pro Leu Asp 
    2615                 2620                 2625             


Phe Glu  Lys Ile Gln Lys Tyr  Val Val Trp Ile Glu  Ala Arg Asp 
    2630                 2635                 2640             


Gly Gly  Phe Pro Pro Phe Ser  Ser Tyr Glu Lys Leu  Asp Ile Thr 
    2645                 2650                 2655             


Val Leu  Asp Val Asn Asp Asn  Ala Pro Ile Phe Lys  Glu Asp Pro 
    2660                 2665                 2670             


Phe Ile  Ser Glu Ile Leu Glu  Asn Leu Ser Pro Arg  Lys Ile Leu 
    2675                 2680                 2685             


Thr Val  Ser Ala Met Asp Lys  Asp Ser Gly Pro Asn  Gly Gln Leu 
    2690                 2695                 2700             


Asp Tyr  Glu Ile Val Asn Gly  Asn Met Glu Asn Ser  Phe Ser Ile 
    2705                 2710                 2715             


Asn His  Ala Thr Gly Glu Ile  Arg Ser Val Arg Pro  Leu Asp Arg 
    2720                 2725                 2730             


Glu Lys  Val Ser His Tyr Val  Leu Thr Ile Lys Ser  Ser Asp Lys 
    2735                 2740                 2745             


Gly Ser  Pro Ser Gln Ser Thr  Ser Val Lys Val Met  Ile Asn Ile 
    2750                 2755                 2760             


Leu Asp  Glu Asn Asp Asn Ala  Pro Arg Phe Ser Gln  Ile Phe Ser 
    2765                 2770                 2775             


Ala His  Val Pro Glu Asn Ser  Pro Leu Gly Tyr Thr  Val Thr Arg 
    2780                 2785                 2790             


Val Thr  Thr Ser Asp Glu Asp  Ile Gly Ile Asn Ala  Ile Ser Arg 
    2795                 2800                 2805             


Tyr Ser  Ile Met Asp Ala Ser  Leu Pro Phe Thr Ile  Asn Pro Ser 
    2810                 2815                 2820             


Thr Gly  Asp Ile Val Ile Ser  Arg Pro Leu Asn Arg  Glu Asp Thr 
    2825                 2830                 2835             


Asp Arg  Tyr Arg Ile Arg Val  Ser Ala His Asp Ser  Gly Trp Thr 
    2840                 2845                 2850             


Val Ser  Thr Asp Val Thr Ile  Phe Val Thr Asp Ile  Asn Asp Asn 
    2855                 2860                 2865             


Ala Pro  Arg Phe Ser Arg Thr  Ser Tyr Tyr Leu Asp  Cys Pro Glu 
    2870                 2875                 2880             


Leu Thr  Glu Ile Gly Ser Lys  Val Thr Gln Val Phe  Ala Thr Asp 
    2885                 2890                 2895             


Pro Asp  Glu Gly Ser Asn Gly  Gln Val Phe Tyr Phe  Ile Lys Ser 
    2900                 2905                 2910             


Gln Ser  Glu Tyr Phe Arg Ile  Asn Ala Thr Thr Gly  Glu Ile Phe 
    2915                 2920                 2925             


Asn Lys  Gln Ile Leu Lys Tyr  Gln Asn Val Thr Gly  Phe Ser Asn 
    2930                 2935                 2940             


Val Asn  Ile Asn Arg His Ser  Phe Ile Val Thr Ser  Ser Asp Arg 
    2945                 2950                 2955             


Gly Lys  Pro Ser Leu Ile Ser  Glu Thr Thr Val Thr  Ile Asn Ile 
    2960                 2965                 2970             


Val Asp  Ser Asn Asp Asn Ala  Pro Gln Phe Leu Lys  Ser Lys Tyr 
    2975                 2980                 2985             


Phe Thr  Pro Val Thr Lys Asn  Val Lys Val Gly Thr  Lys Leu Ile 
    2990                 2995                 3000             


Arg Val  Thr Ala Ile Asp Asp  Lys Asp Phe Gly Leu  Asn Ser Glu 
    3005                 3010                 3015             


Val Glu  Tyr Phe Ile Ser Asn  Asp Asn His Leu Gly  Lys Phe Lys 
    3020                 3025                 3030             


Leu Asp  Asn Asp Thr Gly Trp  Ile Ser Val Ala Ser  Ser Leu Ile 
    3035                 3040                 3045             


Ser Asp  Leu Asn Gln Asn Phe  Phe Ile Thr Val Thr  Ala Lys Asp 
    3050                 3055                 3060             


Lys Gly  Asn Pro Pro Leu Ser  Ser Gln Ala Thr Val  His Ile Thr 
    3065                 3070                 3075             


Val Thr  Glu Glu Asn Tyr His  Thr Pro Glu Phe Ser  Gln Ser His 
    3080                 3085                 3090             


Met Ser  Ala Thr Ile Pro Glu  Ser His Ser Ile Gly  Ser Ile Val 
    3095                 3100                 3105             


Arg Thr  Val Ser Ala Arg Asp  Arg Asp Ala Ala Met  Asn Gly Leu 
    3110                 3115                 3120             


Ile Lys  Tyr Ser Ile Ser Ser  Gly Asn Glu Glu Gly  Ile Phe Ala 
    3125                 3130                 3135             


Ile Asn  Ser Ser Thr Gly Ile  Leu Thr Leu Ala Lys  Ala Leu Asp 
    3140                 3145                 3150             


Tyr Glu  Leu Cys Gln Lys His  Glu Met Thr Ile Ser  Ala Ile Asp 
    3155                 3160                 3165             


Gly Gly  Trp Val Ala Arg Thr  Gly Tyr Cys Ser Val  Thr Val Asn 
    3170                 3175                 3180             


Val Ile  Asp Val Asn Asp Asn  Ser Pro Val Phe Leu  Ser Asp Asp 
    3185                 3190                 3195             


Tyr Phe  Pro Thr Val Leu Glu  Asn Ala Pro Ser Gly  Thr Thr Val 
    3200                 3205                 3210             


Ile His  Leu Asn Ala Thr Asp  Ala Asp Ser Gly Thr  Asn Ala Val 
    3215                 3220                 3225             


Ile Ala  Tyr Thr Val Gln Ser  Ser Asp Ser Asp Leu  Phe Val Ile 
    3230                 3235                 3240             


Asp Pro  Asn Thr Gly Val Ile  Thr Thr Gln Gly Phe  Leu Asp Phe 
    3245                 3250                 3255             


Glu Thr  Lys Gln Ser Tyr His  Leu Thr Val Lys Ala  Phe Asn Val 
    3260                 3265                 3270             


Pro Asp  Glu Glu Arg Cys Ser  Phe Ala Thr Val Asn  Ile Gln Leu 
    3275                 3280                 3285             


Lys Gly  Thr Asn Glu Tyr Val  Pro Arg Phe Val Ser  Lys Leu Tyr 
    3290                 3295                 3300             


Tyr Phe  Glu Ile Ser Glu Ala  Ala Pro Lys Gly Thr  Ile Val Gly 
    3305                 3310                 3315             


Glu Val  Phe Ala Ser Asp Arg  Asp Leu Gly Thr Asp  Gly Glu Val 
    3320                 3325                 3330             


His Tyr  Leu Ile Phe Gly Asn  Ser Arg Lys Lys Gly  Phe Gln Ile 
    3335                 3340                 3345             


Asn Lys  Lys Thr Gly Gln Ile  Tyr Val Ser Gly Ile  Leu Asp Arg 
    3350                 3355                 3360             


Glu Lys  Glu Glu Arg Val Ser  Leu Lys Val Leu Ala  Lys Asn Phe 
    3365                 3370                 3375             


Gly Ser  Ile Arg Gly Ala Asp  Ile Asp Glu Val Thr  Val Asn Val 
    3380                 3385                 3390             


Thr Val  Leu Asp Ala Asn Asp  Pro Pro Ile Phe Thr  Leu Asn Ile 
    3395                 3400                 3405             


Tyr Ser  Val Gln Ile Ser Glu  Gly Val Pro Ile Gly  Thr His Val 
    3410                 3415                 3420             


Thr Phe  Val Ser Ala Phe Asp  Ser Asp Ser Ile Pro  Ser Trp Ser 
    3425                 3430                 3435             


Arg Phe  Ser Tyr Phe Ile Gly  Ser Gly Asn Glu Asn  Gly Ala Phe 
    3440                 3445                 3450             


Ser Ile  Asn Pro Gln Thr Gly  Gln Ile Thr Val Thr  Ala Glu Leu 
    3455                 3460                 3465             


Asp Arg  Glu Thr Leu Pro Ile  Tyr Asn Leu Ser Val  Leu Ala Val 
    3470                 3475                 3480             


Asp Ser  Gly Thr Pro Ser Ala  Thr Gly Ser Ala Ser  Leu Leu Val 
    3485                 3490                 3495             


Thr Leu  Glu Asp Ile Asn Asp  Asn Gly Pro Met Leu  Thr Val Ser 
    3500                 3505                 3510             


Glu Gly  Glu Val Met Glu Asn  Lys Arg Pro Gly Thr  Leu Val Met 
    3515                 3520                 3525             


Thr Leu  Gln Ser Thr Asp Pro  Asp Leu Pro Pro Asn  Gln Gly Pro 
    3530                 3535                 3540             


Phe Thr  Tyr Tyr Leu Leu Ser  Thr Gly Pro Ala Thr  Ser Tyr Phe 
    3545                 3550                 3555             


Ser Leu  Ser Thr Ala Gly Val  Leu Ser Thr Thr Arg  Glu Ile Asp 
    3560                 3565                 3570             


Arg Glu  Gln Ile Ala Asp Phe  Tyr Leu Ser Val Val  Thr Lys Asp 
    3575                 3580                 3585             


Ser Gly  Val Pro Gln Met Ser  Ser Thr Gly Thr Val  His Ile Thr 
    3590                 3595                 3600             


Val Ile  Asp Gln Asn Asp Asn  Pro Ser Gln Ser Arg  Thr Val Glu 
    3605                 3610                 3615             


Ile Phe  Val Asn Tyr Tyr Gly  Asn Leu Phe Pro Gly  Gly Ile Leu 
    3620                 3625                 3630             


Gly Ser  Val Lys Pro Gln Asp  Pro Asp Val Leu Asp  Ser Phe His 
    3635                 3640                 3645             


Cys Ser  Leu Thr Ser Gly Val  Thr Ser Leu Phe Ser  Ile Pro Gly 
    3650                 3655                 3660             


Gly Thr  Cys Asp Leu Asn Ser  Gln Pro Arg Ser Thr  Asp Gly Thr 
    3665                 3670                 3675             


Phe Asp  Leu Thr Val Leu Ser  Asn Asp Gly Val His  Ser Thr Val 
    3680                 3685                 3690             


Thr Ser  Asn Ile Arg Val Phe  Phe Ala Gly Phe Ser  Asn Ala Thr 
    3695                 3700                 3705             


Val Asp  Asn Ser Ile Leu Leu  Arg Leu Gly Val Pro  Thr Val Lys 
    3710                 3715                 3720             


Asp Phe  Leu Thr Asn His Tyr  Leu His Phe Leu Arg  Ile Ala Ser 
    3725                 3730                 3735             


Ser Gln  Leu Thr Gly Leu Gly  Thr Ala Val Gln Leu  Tyr Ser Ala 
    3740                 3745                 3750             


Tyr Glu  Glu Asn Asn Arg Thr  Phe Leu Leu Ala Ala  Val Lys Arg 
    3755                 3760                 3765             


Asn His  Asn Gln Tyr Val Asn  Pro Ser Gly Val Ala  Thr Phe Phe 
    3770                 3775                 3780             


Glu Ser  Ile Lys Glu Ile Leu  Leu Arg Gln Ser Gly  Val Lys Val 
    3785                 3790                 3795             


Glu Ser  Val Asp His Asp Ser  Cys Val His Gly Pro  Cys Gln Asn 
    3800                 3805                 3810             


Gly Gly  Ser Cys Leu Arg Arg  Leu Ala Val Ser Ser  Val Leu Lys 
    3815                 3820                 3825             


Ser Arg  Glu Ser Leu Pro Val  Ile Ile Val Ala Asn  Glu Pro Leu 
    3830                 3835                 3840             


Gln Pro  Phe Leu Cys Lys Cys  Leu Pro Gly Tyr Ala  Gly Ser Trp 
    3845                 3850                 3855             


Cys Glu  Ile Asp Ile Asp Glu  Cys Leu Pro Ser Pro  Cys His Ser 
    3860                 3865                 3870             


Gly Gly  Thr Cys His Asn Leu  Val Gly Gly Phe Ser  Cys Ser Cys 
    3875                 3880                 3885             


Pro Asp  Gly Phe Thr Gly Arg  Ala Cys Glu Arg Asp  Ile Asn Glu 
    3890                 3895                 3900             


Cys Leu  Gln Ser Pro Cys Lys  Asn Gly Ala Ile Cys  Gln Asn Phe 
    3905                 3910                 3915             


Pro Gly  Ser Phe Asn Cys Val  Cys Lys Thr Gly Tyr  Thr Gly Lys 
    3920                 3925                 3930             


Met Cys  Glu Ser Ser Val Asn  Tyr Cys Glu Cys Asn  Pro Cys Phe 
    3935                 3940                 3945             


Asn Gly  Gly Ser Cys Gln Ser  Gly Val Asp Ser Tyr  Tyr Cys His 
    3950                 3955                 3960             


Cys Pro  Phe Gly Val Phe Gly  Lys His Cys Glu Leu  Asn Ser Tyr 
    3965                 3970                 3975             


Gly Phe  Glu Glu Leu Ser Tyr  Met Glu Phe Pro Ser  Leu Asp Pro 
    3980                 3985                 3990             


Asn Asn  Asn Tyr Ile Tyr Val  Lys Phe Ala Thr Ile  Lys Ser His 
    3995                 4000                 4005             


Ala Leu  Leu Leu Tyr Asn Tyr  Asp Asn Gln Thr Gly  Asp Arg Ala 
    4010                 4015                 4020             


Glu Phe  Leu Ala Leu Glu Ile  Ala Glu Glu Arg Leu  Arg Phe Ser 
    4025                 4030                 4035             


Tyr Asn  Leu Gly Ser Gly Thr  Tyr Lys Leu Thr Thr  Met Lys Lys 
    4040                 4045                 4050             


Val Ser  Asp Gly His Phe His  Thr Val Ile Ala Arg  Arg Ala Gly 
    4055                 4060                 4065             


Met Ala  Ala Ser Leu Thr Val  Asp Ser Cys Ser Glu  Asn Gln Glu 
    4070                 4075                 4080             


Pro Gly  Tyr Cys Thr Val Ser  Asn Val Ala Val Ser  Asp Asp Trp 
    4085                 4090                 4095             


Thr Leu  Asp Val Gln Pro Asn  Arg Val Thr Val Gly  Gly Ile Arg 
    4100                 4105                 4110             


Ser Leu  Glu Pro Ile Leu Gln  Arg Arg Gly His Val  Glu Ser His 
    4115                 4120                 4125             


Asp Phe  Val Gly Cys Ile Met  Glu Phe Ala Val Asn  Gly Arg Pro 
    4130                 4135                 4140             


Leu Glu  Pro Ser Gln Ala Leu  Ala Ala Gln Gly Ile  Leu Asp Gln 
    4145                 4150                 4155             


Cys Pro  Arg Leu Glu Gly Ala  Cys Thr Arg Ser Pro  Cys Gln His 
    4160                 4165                 4170             


Gly Gly  Thr Cys Met Asp Tyr  Trp Ser Trp Gln Gln  Cys His Cys 
    4175                 4180                 4185             


Lys Glu  Gly Leu Thr Gly Lys  Tyr Cys Glu Lys Ser  Val Thr Pro 
    4190                 4195                 4200             


Asp Thr  Ala Leu Ser Leu Glu  Gly Lys Gly Arg Leu  Asp Tyr His 
    4205                 4210                 4215             


Met Ser  Gln Asn Glu Lys Arg  Glu Tyr Leu Leu Arg  Gln Ser Leu 
    4220                 4225                 4230             


Arg Gly  Ala Met Leu Glu Pro  Phe Gly Val Asn Ser  Leu Glu Val 
    4235                 4240                 4245             


Lys Phe  Arg Thr Arg Ser Glu  Asn Gly Val Leu Ile  His Ile Gln 
    4250                 4255                 4260             


Glu Ser  Ser Asn Tyr Thr Thr  Val Lys Ile Lys Asn  Gly Lys Val 
    4265                 4270                 4275             


Tyr Phe  Thr Ser Asp Ala Gly  Ile Ala Gly Lys Val  Glu Arg Asn 
    4280                 4285                 4290             


Ile Pro  Glu Val Tyr Val Ala  Asp Gly His Trp His  Thr Phe Leu 
    4295                 4300                 4305             


Ile Gly  Lys Asn Gly Thr Ala  Thr Val Leu Ser Val  Asp Arg Ile 
    4310                 4315                 4320             


Tyr Asn  Arg Asp Ile Ile His  Pro Thr Gln Asp Phe  Gly Gly Leu 
    4325                 4330                 4335             


Asp Val  Leu Thr Ile Ser Leu  Gly Gly Ile Pro Pro  Asn Gln Ala 
    4340                 4345                 4350             


His Arg  Asp Ala Gln Thr Ala  Gly Phe Asp Gly Cys  Ile Ala Ser 
    4355                 4360                 4365             


Met Trp  Tyr Gly Gly Glu Ser  Leu Pro Phe Ser Gly  Lys His Ser 
    4370                 4375                 4380             


Leu Ala  Ser Ile Ser Lys Thr  Asp Pro Ser Val Lys  Ile Gly Cys 
    4385                 4390                 4395             


Arg Gly  Pro Asn Ile Cys Ala  Ser Asn Pro Cys Trp  Gly Asp Leu 
    4400                 4405                 4410             


Leu Cys  Ile Asn Gln Trp Tyr  Ala Tyr Arg Cys Val  Pro Pro Gly 
    4415                 4420                 4425             


Asp Cys  Ala Ser His Pro Cys  Gln Asn Gly Gly Ser  Cys Glu Pro 
    4430                 4435                 4440             


Gly Leu  His Ser Gly Phe Thr  Cys Ser Cys Pro Asp  Ser His Thr 
    4445                 4450                 4455             


Gly Arg  Thr Cys Glu Met Val  Val Ala Cys Leu Gly  Val Leu Cys 
    4460                 4465                 4470             


Pro Gln  Gly Lys Val Cys Lys  Ala Gly Ser Pro Ala  Gly His Val 
    4475                 4480                 4485             


Cys Val  Leu Ser Gln Gly Pro  Glu Glu Ile Ser Leu  Pro Leu Trp 
    4490                 4495                 4500             


Ala Val  Pro Ala Ile Val Gly  Ser Cys Ala Thr Val  Leu Ala Leu 
    4505                 4510                 4515             


Leu Val  Leu Ser Leu Ile Leu  Cys Asn Gln Cys Arg  Gly Lys Lys 
    4520                 4525                 4530             


Ala Lys  Asn Pro Lys Glu Glu  Lys Lys Pro Lys Glu  Lys Lys Lys 
    4535                 4540                 4545             


Lys Gly  Ser Glu Asn Val Ala  Phe Asp Asp Pro Asp  Asn Ile Pro 
    4550                 4555                 4560             


Pro Tyr  Gly Asp Asp Met Thr  Val Arg Lys Gln Pro  Glu Gly Asn 
    4565                 4570                 4575             


Pro Lys  Pro Asp Ile Ile Glu  Arg Glu Asn Pro Tyr  Leu Ile Tyr 
    4580                 4585                 4590             


Asp Glu  Thr Asp Ile Pro His  Asn Ser Glu Thr Ile  Pro Ser Ala 
    4595                 4600                 4605             


Pro Leu  Ala Ser Pro Glu Gln  Glu Ile Glu His Tyr  Asp Ile Asp 
    4610                 4615                 4620             


Asn Ala  Ser Ser Ile Ala Pro  Ser Asp Ala Asp Ile  Ile Gln His 
    4625                 4630                 4635             


Tyr Lys  Gln Phe Arg Ser His  Thr Pro Lys Phe Ser  Ile Gln Arg 
    4640                 4645                 4650             


His Ser  Pro Leu Gly Phe Ala  Arg Gln Ser Pro Met  Pro Leu Gly 
    4655                 4660                 4665             


Ala Ser  Ser Leu Thr Tyr Gln  Pro Ser Tyr Gly Gln  Gly Leu Arg 
    4670                 4675                 4680             


Thr Ser  Ser Leu Ser His Ser  Ala Cys Pro Thr Pro  Asn Pro Leu 
    4685                 4690                 4695             


Ser Arg  His Ser Pro Ala Pro  Phe Ser Lys Ser Ser  Thr Phe Tyr 
    4700                 4705                 4710             


Arg Asn  Ser Pro Ala Arg Glu  Leu His Leu Pro Ile  Arg Asp Gly 
    4715                 4720                 4725             


Asn Thr  Leu Glu Met His Gly  Asp Thr Cys Gln Pro  Gly Ile Phe 
    4730                 4735                 4740             


Asn Tyr  Ala Thr Arg Leu Gly  Arg Arg Ser Lys Ser  Pro Gln Ala 
    4745                 4750                 4755             


Met Ala  Ser His Gly Ser Arg  Pro Gly Ser Arg Leu  Lys Gln Pro 
    4760                 4765                 4770             


Ile Gly  Gln Ile Pro Leu Glu  Ser Ser Pro Pro Val  Gly Leu Ser 
    4775                 4780                 4785             


Ile Glu  Glu Val Glu Arg Leu  Asn Thr Pro Arg Pro  Arg Asn Pro 
    4790                 4795                 4800             


Ser Ile  Cys Ser Ala Asp His  Gly Arg Ser Ser Ser  Glu Glu Asp 
    4805                 4810                 4815             


Cys Arg  Arg Pro Leu Ser Arg  Thr Arg Asn Pro Ala  Asp Gly Ile 
    4820                 4825                 4830             


Pro Ala  Pro Glu Ser Ser Ser  Asp Ser Asp Ser His  Glu Ser Phe 
    4835                 4840                 4845             


Thr Cys  Ser Glu Met Glu Tyr  Asp Arg Glu Lys Pro  Met Val Tyr 
    4850                 4855                 4860             


Thr Ser  Arg Met Pro Lys Leu  Ser Gln Val Asn Glu  Ser Asp Ala 
    4865                 4870                 4875             


Asp Asp  Glu Asp Asn Tyr Gly  Ala Arg Leu Lys Pro  Arg Arg Tyr 
    4880                 4885                 4890             


His Gly  Arg Arg Ala Glu Gly  Gly Pro Val Gly Thr  Gln Ala Ala 
    4895                 4900                 4905             


Ala Pro  Gly Thr Ala Asp Asn  Thr Leu Pro Met Lys  Leu Gly Gln 
    4910                 4915                 4920             


Gln Ala  Gly Thr Phe Asn Trp  Asp Asn Leu Leu Asn  Trp Gly Pro 
    4925                 4930                 4935             


Gly Phe  Gly His Tyr Val Asp  Val Phe Lys Asp Leu  Ala Ser Leu 
    4940                 4945                 4950             


Pro Glu  Lys Ala Ala Ala Asn  Glu Glu Gly Lys Ala  Gly Thr Thr 
    4955                 4960                 4965             


Lys Pro  Val Pro Lys Asp Gly  Glu Ala Glu Gln Tyr  Val 
    4970                 4975                 4980     


<210>  3863
<211>  308
<212>  PRT
<213>  homo sapiens

<400>  3863

Met Asp Glu Gln Thr Gly Arg Leu Arg Leu Asp Thr Tyr Cys Met Ser 
1               5                   10                  15      


Ala Lys Gln Ile Trp Ala Trp Ser Lys Cys Ser Gly Arg Leu Trp Asp 
            20                  25                  30          


Glu His Met Lys Trp Met Glu Gly Trp Thr Asp Arg Trp Thr Asp Gly 
        35                  40                  45              


Trp Met Asp Gly Trp Met Asp Glu Trp Ser Pro Thr Pro Ala Leu Arg 
    50                  55                  60                  


Ser Tyr Gly Gly Gly Leu Ser Gln Gln Thr Phe Ile Phe Thr Asp Gly 
65                  70                  75                  80  


Glu Asp Glu Ala Leu Ala Arg His Thr Gly Asn Val Val Ile Thr Asn 
                85                  90                  95      


Cys Ser Ala Ala His Ser Arg Gln Ala Leu Ser Cys Lys Met Ala Val 
            100                 105                 110         


Glu Tyr Asp Arg Phe Ile Glu Ser Gly Arg Lys Trp Phe Cys His Val 
        115                 120                 125             


Asp Asp Asp Asn Tyr Val Asn Leu Arg Ala Leu Leu Arg Leu Leu Ala 
    130                 135                 140                 


Ser Tyr Pro His Thr Arg Asp Val Tyr Val Gly Lys Pro Ser Leu Asp 
145                 150                 155                 160 


Arg Pro Ile Gln Ala Met Glu Arg Val Ser Glu Asn Lys Val Arg Pro 
                165                 170                 175     


Val His Phe Trp Phe Ala Thr Gly Gly Ala Gly Phe Cys Ile Ser Arg 
            180                 185                 190         


Gly Leu Ala Leu Lys Met Ser Pro Trp Ala Ser Gly Gly His Phe Met 
        195                 200                 205             


Asn Thr Ala Glu Arg Ile Arg Leu Pro Asp Asp Cys Thr Ile Gly Tyr 
    210                 215                 220                 


Ile Val Glu Ala Leu Leu Gly Val Pro Leu Ile Arg Ser Gly Leu Phe 
225                 230                 235                 240 


His Ser His Leu Glu Asn Leu Gln Gln Val Pro Thr Ser Glu Leu His 
                245                 250                 255     


Glu Gln Val Thr Leu Ser Tyr Gly Met Phe Glu Asn Lys Arg Asn Ala 
            260                 265                 270         


Val His Val Lys Gly Pro Phe Ser Val Glu Ala Asp Pro Ser Arg Phe 
        275                 280                 285             


Arg Ser Ile His Cys His Leu Tyr Pro Asp Thr Pro Trp Cys Pro Arg 
    290                 295                 300                 


Thr Ala Ile Phe 
305             


<210>  3864
<211>  754
<212>  PRT
<213>  homo sapiens

<400>  3864

Met Gly Ile Lys Val Gln Arg Pro Arg Cys Phe Phe Asp Ile Ala Ile 
1               5                   10                  15      


Asn Asn Gln Pro Ala Gly Arg Val Val Phe Glu Leu Phe Ser Asp Val 
            20                  25                  30          


Cys Pro Lys Thr Cys Glu Asn Phe Arg Cys Leu Cys Thr Gly Glu Lys 
        35                  40                  45              


Gly Thr Gly Lys Ser Thr Gln Lys Pro Leu His Tyr Lys Ser Cys Leu 
    50                  55                  60                  


Phe His Arg Val Val Lys Asp Phe Met Val Gln Gly Gly Asp Phe Ser 
65                  70                  75                  80  


Glu Gly Asn Gly Arg Gly Gly Glu Ser Ile Tyr Gly Gly Phe Phe Glu 
                85                  90                  95      


Asp Glu Ser Phe Ala Val Lys His Asn Lys Glu Phe Leu Leu Ser Met 
            100                 105                 110         


Ala Asn Arg Gly Lys Asp Thr Asn Gly Ser Gln Phe Phe Ile Thr Thr 
        115                 120                 125             


Lys Pro Thr Pro His Leu Asp Gly His His Val Val Phe Gly Gln Val 
    130                 135                 140                 


Ile Ser Gly Gln Glu Val Val Arg Glu Ile Glu Asn Gln Lys Thr Asp 
145                 150                 155                 160 


Ala Ala Ser Lys Pro Phe Ala Glu Val Arg Ile Leu Ser Cys Gly Glu 
                165                 170                 175     


Leu Ile Pro Lys Ser Lys Val Lys Lys Glu Glu Lys Lys Arg His Lys 
            180                 185                 190         


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Asp Ser Asp Ser Ser Ser 
        195                 200                 205             


Asp Ser Gln Ser Ser Ser Asp Ser Ser Asp Ser Glu Ser Ala Thr Glu 
    210                 215                 220                 


Glu Lys Ser Lys Lys Arg Lys Lys Lys His Arg Lys Asn Ser Arg Lys 
225                 230                 235                 240 


His Lys Lys Glu Lys Lys Lys Arg Lys Lys Ser Lys Lys Ser Ala Ser 
                245                 250                 255     


Ser Glu Ser Glu Ala Glu Asn Leu Glu Ala Gln Pro Gln Ser Thr Val 
            260                 265                 270         


Arg Pro Glu Glu Ile Pro Pro Ile Pro Glu Asn Arg Phe Leu Met Arg 
        275                 280                 285             


Lys Ser Pro Pro Lys Ala Asp Glu Lys Glu Arg Lys Asn Arg Glu Arg 
    290                 295                 300                 


Glu Arg Glu Arg Glu Cys Asn Pro Pro Asn Ser Gln Pro Ala Ser Tyr 
305                 310                 315                 320 


Gln Arg Arg Leu Leu Val Thr Arg Ser Gly Arg Lys Ile Lys Gly Arg 
                325                 330                 335     


Gly Pro Arg Arg Tyr Arg Thr Pro Ser Arg Ser Arg Ser Arg Asp Arg 
            340                 345                 350         


Phe Arg Arg Ser Glu Thr Pro Pro His Trp Arg Gln Glu Met Gln Arg 
        355                 360                 365             


Ala Gln Arg Met Arg Val Ser Ser Gly Glu Arg Trp Ile Lys Gly Asp 
    370                 375                 380                 


Lys Ser Glu Leu Asn Glu Ile Lys Glu Asn Gln Arg Ser Pro Val Arg 
385                 390                 395                 400 


Val Lys Glu Arg Lys Ile Thr Asp His Arg Asn Val Ser Glu Ser Pro 
                405                 410                 415     


Asn Arg Lys Asn Glu Lys Glu Lys Lys Val Lys Asp His Lys Ser Asn 
            420                 425                 430         


Ser Lys Glu Arg Asp Ile Arg Arg Asn Ser Glu Lys Asp Asp Lys Tyr 
        435                 440                 445             


Lys Asn Lys Val Lys Lys Arg Ala Lys Ser Lys Ser Arg Ser Lys Ser 
    450                 455                 460                 


Lys Glu Lys Ser Lys Ser Lys Glu Arg Asp Ser Lys His Asn Arg Asn 
465                 470                 475                 480 


Glu Glu Lys Arg Met Arg Ser Arg Ser Lys Gly Arg Asp His Glu Asn 
                485                 490                 495     


Val Lys Glu Lys Glu Lys Gln Ser Asp Ser Lys Gly Lys Asp Gln Glu 
            500                 505                 510         


Arg Ser Arg Ser Lys Glu Lys Ser Lys Gln Leu Glu Ser Lys Ser Asn 
        515                 520                 525             


Glu His Asp His Ser Lys Ser Lys Glu Lys Asp Arg Arg Ala Gln Ser 
    530                 535                 540                 


Arg Ser Arg Glu Cys Asp Ile Thr Lys Gly Lys His Ser Tyr Asn Ser 
545                 550                 555                 560 


Arg Thr Arg Glu Arg Ser Arg Ser Arg Asp Arg Ser Arg Arg Val Arg 
                565                 570                 575     


Ser Arg Thr His Asp Arg Asp Arg Ser Arg Ser Lys Glu Tyr His Arg 
            580                 585                 590         


Tyr Arg Glu Gln Glu Tyr Arg Arg Arg Gly Arg Ser Arg Ser Arg Glu 
        595                 600                 605             


Arg Arg Thr Pro Pro Gly Arg Ser Arg Ser Lys Asp Arg Arg Arg Arg 
    610                 615                 620                 


Arg Arg Asp Ser Arg Ser Ser Glu Arg Glu Glu Ser Gln Ser Arg Asn 
625                 630                 635                 640 


Lys Asp Lys Tyr Arg Asn Gln Glu Ser Lys Ser Ser His Arg Lys Glu 
                645                 650                 655     


Asn Ser Glu Ser Glu Lys Arg Met Tyr Ser Lys Ser Arg Asp His Asn 
            660                 665                 670         


Ser Ser Asn Asn Ser Arg Glu Lys Lys Ala Asp Arg Asp Gln Ser Pro 
        675                 680                 685             


Phe Ser Lys Ile Lys Gln Ser Ser Gln Asp Asn Glu Leu Lys Ser Ser 
    690                 695                 700                 


Met Leu Lys Asn Lys Glu Asp Glu Lys Ile Arg Ser Ser Val Glu Lys 
705                 710                 715                 720 


Glu Asn Gln Lys Ser Lys Gly Gln Glu Asn Asp His Val His Glu Lys 
                725                 730                 735     


Asn Lys Lys Phe Asp His Glu Ser Ser Pro Gly Thr Asp Glu Asp Lys 
            740                 745                 750         


Ser Gly 
        


<210>  3865
<211>  380
<212>  PRT
<213>  homo sapiens

<400>  3865

Met Gly Ala Phe Leu Asp Lys Pro Lys Thr Glu Lys His Asn Ala His 
1               5                   10                  15      


Gly Ala Gly Asn Gly Leu Arg Tyr Gly Leu Ser Ser Met Gln Gly Trp 
            20                  25                  30          


Arg Val Glu Met Glu Asp Ala His Thr Ala Val Val Gly Ile Pro His 
        35                  40                  45              


Gly Leu Glu Asp Trp Ser Phe Phe Ala Val Tyr Asp Gly His Ala Gly 
    50                  55                  60                  


Ser Arg Val Ala Asn Tyr Cys Ser Thr His Leu Leu Glu His Ile Thr 
65                  70                  75                  80  


Thr Asn Glu Asp Phe Arg Ala Ala Gly Lys Ser Gly Ser Ala Leu Glu 
                85                  90                  95      


Leu Ser Val Glu Asn Val Lys Asn Gly Ile Arg Thr Gly Phe Leu Lys 
            100                 105                 110         


Ile Asp Glu Tyr Met Arg Asn Phe Ser Asp Leu Arg Asn Gly Met Asp 
        115                 120                 125             


Arg Ser Gly Ser Thr Ala Val Gly Val Met Ile Ser Pro Lys His Ile 
    130                 135                 140                 


Tyr Phe Ile Asn Cys Gly Asp Ser Arg Ala Val Leu Tyr Arg Asn Gly 
145                 150                 155                 160 


Gln Val Cys Phe Ser Thr Gln Asp His Lys Pro Cys Asn Pro Arg Glu 
                165                 170                 175     


Lys Glu Arg Ile Gln Asn Ala Gly Gly Ser Val Met Ile Gln Arg Val 
            180                 185                 190         


Asn Gly Ser Leu Ala Val Ser Arg Ala Leu Gly Asp Tyr Asp Tyr Lys 
        195                 200                 205             


Cys Val Asp Gly Lys Gly Pro Thr Glu Gln Leu Val Ser Pro Glu Pro 
    210                 215                 220                 


Glu Val Tyr Glu Ile Leu Arg Ala Glu Glu Asp Glu Phe Ile Ile Leu 
225                 230                 235                 240 


Ala Cys Asp Gly Ile Trp Asp Val Met Ser Asn Glu Glu Leu Cys Glu 
                245                 250                 255     


Tyr Val Lys Ser Arg Leu Glu Val Ser Asp Asp Leu Glu Asn Val Cys 
            260                 265                 270         


Asn Trp Val Val Asp Thr Cys Leu His Lys Gly Ser Arg Asp Asn Met 
        275                 280                 285             


Ser Ile Val Leu Val Cys Phe Ser Asn Ala Pro Lys Val Ser Asp Glu 
    290                 295                 300                 


Ala Val Lys Lys Asp Ser Glu Leu Asp Lys His Leu Glu Ser Arg Val 
305                 310                 315                 320 


Glu Glu Ile Met Glu Lys Ser Gly Glu Glu Gly Met Pro Asp Leu Ala 
                325                 330                 335     


His Val Met Arg Ile Leu Ser Ala Glu Asn Ile Pro Asn Leu Pro Pro 
            340                 345                 350         


Gly Gly Gly Leu Ala Gly Lys Arg Asn Val Ile Glu Ala Val Tyr Ser 
        355                 360                 365             


Arg Leu Asn Pro His Arg Glu Ser Asp Gly Gln Lys 
    370                 375                 380 


<210>  3866
<211>  1582
<212>  PRT
<213>  homo sapiens

<400>  3866

Met Gly Ser Lys Arg Arg Arg Ala Thr Ser Pro Ser Ser Ser Val Ser 
1               5                   10                  15      


Gly Asp Phe Asp Asp Gly His His Ser Val Ser Thr Pro Gly Pro Ser 
            20                  25                  30          


Arg Lys Arg Arg Arg Leu Ser Asn Leu Pro Thr Val Asp Pro Ile Ala 
        35                  40                  45              


Val Cys His Glu Leu Tyr Asn Thr Ile Arg Asp Tyr Lys Asp Glu Gln 
    50                  55                  60                  


Gly Arg Leu Leu Cys Glu Leu Phe Ile Arg Ala Pro Lys Arg Arg Asn 
65                  70                  75                  80  


Gln Pro Asp Tyr Tyr Glu Val Val Ser Gln Pro Ile Asp Leu Met Lys 
                85                  90                  95      


Ile Gln Gln Lys Leu Lys Met Glu Glu Tyr Asp Asp Val Asn Leu Leu 
            100                 105                 110         


Thr Ala Asp Phe Gln Leu Leu Phe Asn Asn Ala Lys Ser Tyr Tyr Lys 
        115                 120                 125             


Pro Asp Ser Pro Glu Tyr Lys Ala Ala Cys Lys Leu Trp Asp Leu Tyr 
    130                 135                 140                 


Leu Arg Thr Arg Asn Glu Phe Val Gln Lys Gly Glu Ala Asp Asp Glu 
145                 150                 155                 160 


Asp Asp Asp Glu Asp Gly Gln Asp Asn Gln Gly Thr Val Thr Glu Gly 
                165                 170                 175     


Ser Ser Pro Ala Tyr Leu Lys Glu Ile Leu Glu Gln Leu Leu Glu Ala 
            180                 185                 190         


Ile Val Val Ala Thr Asn Pro Ser Gly Arg Leu Ile Ser Glu Leu Phe 
        195                 200                 205             


Gln Lys Leu Pro Ser Lys Val Gln Tyr Pro Asp Tyr Tyr Ala Ile Ile 
    210                 215                 220                 


Lys Glu Pro Ile Asp Leu Lys Thr Ile Ala Gln Arg Ile Gln Asn Gly 
225                 230                 235                 240 


Ser Tyr Lys Ser Ile His Ala Met Ala Lys Asp Ile Asp Leu Leu Ala 
                245                 250                 255     


Lys Asn Ala Lys Thr Tyr Asn Glu Pro Gly Ser Gln Val Phe Lys Asp 
            260                 265                 270         


Ala Asn Ser Ile Lys Lys Ile Phe Tyr Met Lys Lys Ala Glu Ile Glu 
        275                 280                 285             


His His Glu Met Ala Lys Ser Ser Leu Arg Met Arg Thr Pro Ser Asn 
    290                 295                 300                 


Leu Ala Ala Ala Arg Leu Thr Gly Pro Ser His Ser Lys Gly Ser Leu 
305                 310                 315                 320 


Gly Glu Glu Arg Asn Pro Thr Ser Lys Tyr Tyr Arg Asn Lys Arg Ala 
                325                 330                 335     


Val Gln Gly Gly Arg Leu Ser Ala Ile Thr Met Ala Leu Gln Tyr Gly 
            340                 345                 350         


Ser Glu Ser Glu Glu Asp Ala Ala Leu Ala Ala Ala Arg Tyr Glu Glu 
        355                 360                 365             


Gly Glu Ser Glu Ala Glu Ser Ile Thr Ser Phe Met Asp Val Ser Asn 
    370                 375                 380                 


Pro Phe Tyr Gln Leu Tyr Asp Thr Val Arg Ser Cys Arg Asn Asn Gln 
385                 390                 395                 400 


Gly Gln Leu Ile Ala Glu Pro Phe Tyr His Leu Pro Ser Lys Lys Lys 
                405                 410                 415     


Tyr Pro Asp Tyr Tyr Gln Gln Ile Lys Met Pro Ile Ser Leu Gln Gln 
            420                 425                 430         


Ile Arg Thr Lys Leu Lys Asn Gln Glu Tyr Glu Thr Leu Asp His Leu 
        435                 440                 445             


Glu Cys Asp Leu Asn Leu Met Phe Glu Asn Ala Lys Arg Tyr Asn Val 
    450                 455                 460                 


Pro Asn Ser Ala Ile Tyr Lys Arg Val Leu Lys Leu Gln Gln Val Met 
465                 470                 475                 480 


Gln Ala Lys Lys Lys Glu Leu Ala Arg Arg Asp Asp Ile Glu Asp Gly 
                485                 490                 495     


Asp Ser Met Ile Ser Ser Ala Thr Ser Asp Thr Gly Ser Ala Lys Arg 
            500                 505                 510         


Lys Ser Lys Lys Asn Ile Arg Lys Gln Arg Met Lys Ile Leu Phe Asn 
        515                 520                 525             


Val Val Leu Glu Ala Arg Glu Pro Gly Ser Gly Arg Arg Leu Cys Asp 
    530                 535                 540                 


Leu Phe Met Val Lys Pro Ser Lys Lys Asp Tyr Pro Asp Tyr Tyr Lys 
545                 550                 555                 560 


Ile Ile Leu Glu Pro Met Asp Leu Lys Ile Ile Glu His Asn Ile Arg 
                565                 570                 575     


Asn Asp Lys Tyr Ala Gly Glu Glu Gly Met Ile Glu Asp Met Lys Leu 
            580                 585                 590         


Met Phe Arg Asn Ala Arg His Tyr Asn Glu Glu Gly Ser Gln Val Tyr 
        595                 600                 605             


Asn Asp Ala His Ile Leu Glu Lys Leu Leu Lys Glu Lys Arg Lys Glu 
    610                 615                 620                 


Leu Gly Pro Leu Pro Asp Asp Asp Asp Met Ala Ser Pro Lys Leu Lys 
625                 630                 635                 640 


Leu Ser Arg Lys Ser Gly Ile Ser Pro Lys Lys Ser Lys Tyr Met Thr 
                645                 650                 655     


Pro Met Gln Gln Lys Leu Asn Glu Val Tyr Glu Ala Val Lys Asn Tyr 
            660                 665                 670         


Thr Asp Lys Arg Gly Arg Arg Leu Ser Ala Ile Phe Leu Arg Leu Pro 
        675                 680                 685             


Ser Arg Ser Glu Leu Pro Asp Tyr Tyr Leu Thr Ile Lys Lys Pro Met 
    690                 695                 700                 


Asp Met Glu Lys Ile Arg Ser His Met Met Ala Asn Lys Tyr Gln Asp 
705                 710                 715                 720 


Ile Asp Ser Met Val Glu Asp Phe Val Met Met Phe Asn Asn Ala Cys 
                725                 730                 735     


Thr Tyr Asn Glu Pro Glu Ser Leu Ile Tyr Lys Asp Ala Leu Val Leu 
            740                 745                 750         


His Lys Val Leu Leu Glu Thr Arg Arg Asp Leu Glu Gly Asp Glu Asp 
        755                 760                 765             


Ser His Val Pro Asn Val Thr Leu Leu Ile Gln Glu Leu Ile His Asn 
    770                 775                 780                 


Leu Phe Val Ser Val Met Ser His Gln Asp Asp Glu Gly Arg Cys Tyr 
785                 790                 795                 800 


Ser Asp Ser Leu Ala Glu Ile Pro Ala Val Asp Pro Asn Phe Pro Asn 
                805                 810                 815     


Lys Pro Pro Leu Thr Phe Asp Ile Ile Arg Lys Asn Val Glu Asn Asn 
            820                 825                 830         


Arg Tyr Arg Arg Leu Asp Leu Phe Gln Glu His Met Phe Glu Val Leu 
        835                 840                 845             


Glu Arg Ala Arg Arg Met Asn Arg Thr Asp Ser Glu Ile Tyr Glu Asp 
    850                 855                 860                 


Ala Val Glu Leu Gln Gln Phe Phe Ile Lys Ile Arg Asp Glu Leu Cys 
865                 870                 875                 880 


Lys Asn Gly Glu Ile Leu Leu Ser Pro Ala Leu Ser Tyr Thr Thr Lys 
                885                 890                 895     


His Leu His Asn Asp Val Glu Lys Glu Arg Lys Glu Lys Leu Pro Lys 
            900                 905                 910         


Glu Ile Glu Glu Asp Lys Leu Lys Arg Glu Glu Glu Lys Arg Glu Ala 
        915                 920                 925             


Glu Lys Ser Glu Asp Ser Ser Gly Ala Ala Gly Leu Ser Gly Leu His 
    930                 935                 940                 


Arg Thr Tyr Ser Gln Asp Cys Ser Phe Lys Asn Ser Met Tyr His Val 
945                 950                 955                 960 


Gly Asp Tyr Val Tyr Val Glu Pro Ala Glu Ala Asn Leu Gln Pro His 
                965                 970                 975     


Ile Val Cys Ile Glu Arg Leu Trp Glu Asp Ser Ala Glu Lys Glu Val 
            980                 985                 990         


Phe Lys Ser Asp Tyr Tyr Asn Lys  Val Pro Val Ser Lys  Ile Leu Gly 
        995                 1000                 1005             


Lys Cys  Val Val Met Phe Val  Lys Glu Tyr Phe Lys  Leu Cys Pro 
    1010                 1015                 1020             


Glu Asn  Phe Arg Asp Glu Asp  Val Phe Val Cys Glu  Ser Arg Tyr 
    1025                 1030                 1035             


Ser Ala  Lys Thr Lys Ser Phe  Lys Lys Ile Lys Leu  Trp Thr Met 
    1040                 1045                 1050             


Pro Ile  Ser Ser Val Arg Phe  Val Pro Arg Asp Val  Pro Leu Pro 
    1055                 1060                 1065             


Val Val  Arg Val Ala Ser Val  Phe Ala Asn Ala Asp  Lys Gly Asp 
    1070                 1075                 1080             


Asp Glu  Lys Asn Thr Asp Asn  Ser Glu Asp Ser Arg  Ala Glu Asp 
    1085                 1090                 1095             


Asn Phe  Asn Leu Glu Lys Glu  Lys Glu Asp Val Pro  Val Glu Met 
    1100                 1105                 1110             


Ser Asn  Gly Glu Pro Gly Cys  His Tyr Phe Glu Gln  Leu His Tyr 
    1115                 1120                 1125             


Asn Asp  Met Trp Leu Lys Val  Gly Asp Cys Val Phe  Ile Lys Ser 
    1130                 1135                 1140             


His Gly  Leu Val Arg Pro Arg  Val Gly Arg Ile Glu  Lys Val Trp 
    1145                 1150                 1155             


Val Arg  Asp Gly Ala Ala Tyr  Phe Tyr Gly Pro Ile  Phe Ile His 
    1160                 1165                 1170             


Pro Glu  Glu Thr Glu His Glu  Pro Thr Lys Met Phe  Tyr Lys Lys 
    1175                 1180                 1185             


Glu Val  Phe Leu Ser Asn Leu  Glu Glu Thr Cys Pro  Met Thr Cys 
    1190                 1195                 1200             


Ile Leu  Gly Lys Cys Ala Val  Leu Ser Phe Lys Asp  Phe Leu Ser 
    1205                 1210                 1215             


Cys Arg  Pro Thr Glu Ile Pro  Glu Asn Asp Ile Leu  Leu Cys Glu 
    1220                 1225                 1230             


Ser Arg  Tyr Asn Glu Ser Asp  Lys Gln Met Lys Lys  Phe Lys Gly 
    1235                 1240                 1245             


Leu Lys  Arg Phe Ser Leu Ser  Ala Lys Val Val Asp  Asp Glu Ile 
    1250                 1255                 1260             


Tyr Tyr  Phe Arg Lys Pro Ile  Val Pro Gln Lys Glu  Pro Ser Pro 
    1265                 1270                 1275             


Leu Leu  Glu Lys Lys Ile Gln  Leu Leu Glu Ala Lys  Phe Ala Glu 
    1280                 1285                 1290             


Leu Glu  Gly Gly Asp Asp Asp  Ile Glu Glu Met Gly  Glu Glu Asp 
    1295                 1300                 1305             


Ser Glu  Ser Thr Pro Lys Ser  Ala Lys Gly Ser Ala  Lys Lys Glu 
    1310                 1315                 1320             


Gly Ser  Lys Arg Lys Ile Asn  Met Ser Gly Tyr Ile  Leu Phe Ser 
    1325                 1330                 1335             


Ser Glu  Met Arg Ala Val Ile  Lys Ala Gln His Pro  Asp Tyr Ser 
    1340                 1345                 1350             


Phe Gly  Glu Leu Ser Arg Leu  Val Gly Thr Glu Trp  Arg Asn Leu 
    1355                 1360                 1365             


Glu Thr  Ala Lys Lys Ala Glu  Tyr Glu Gly Met Met  Gly Gly Tyr 
    1370                 1375                 1380             


Pro Pro  Gly Leu Pro Pro Leu  Gln Gly Pro Val Asp  Gly Leu Val 
    1385                 1390                 1395             


Ser Met  Gly Ser Met Gln Pro  Leu His Pro Gly Gly  Pro Pro Pro 
    1400                 1405                 1410             


His His  Leu Pro Pro Gly Val  Pro Gly Leu Pro Gly  Ile Pro Pro 
    1415                 1420                 1425             


Pro Gly  Val Met Asn Gln Gly  Val Ala Pro Met Val  Gly Thr Pro 
    1430                 1435                 1440             


Ala Pro  Gly Gly Ser Pro Tyr  Gly Gln Gln Val Gly  Val Leu Gly 
    1445                 1450                 1455             


Pro Pro  Gly Gln Gln Ala Pro  Pro Pro Tyr Pro Gly  Pro His Pro 
    1460                 1465                 1470             


Ala Gly  Pro Pro Val Ile Gln  Gln Pro Thr Thr Pro  Met Phe Val 
    1475                 1480                 1485             


Ala Pro  Pro Pro Lys Thr Gln  Arg Leu Leu His Ser  Glu Ala Tyr 
    1490                 1495                 1500             


Leu Lys  Tyr Ile Glu Gly Leu  Ser Ala Glu Ser Asn  Ser Ile Ser 
    1505                 1510                 1515             


Lys Trp  Asp Gln Thr Leu Ala  Ala Arg Arg Arg Asp  Val His Leu 
    1520                 1525                 1530             


Ser Lys  Glu Gln Glu Ser Arg  Leu Pro Ser His Trp  Leu Lys Ser 
    1535                 1540                 1545             


Lys Gly  Ala His Thr Thr Met  Ala Asp Ala Leu Trp  Arg Leu Arg 
    1550                 1555                 1560             


Asp Leu  Met Leu Arg Asp Thr  Leu Asn Ile Arg Gln  Ala Tyr Asn 
    1565                 1570                 1575             


Leu Glu  Asn Val 
    1580         


<210>  3867
<211>  325
<212>  PRT
<213>  homo sapiens

<400>  3867

Met Val Cys Gly Ser Pro Gly Gly Met Leu Leu Leu Arg Ala Gly Leu 
1               5                   10                  15      


Leu Ala Leu Ala Ala Leu Cys Leu Leu Arg Val Pro Gly Ala Arg Ala 
            20                  25                  30          


Ala Ala Cys Glu Pro Val Arg Ile Pro Leu Cys Lys Ser Leu Pro Trp 
        35                  40                  45              


Asn Met Thr Lys Met Pro Asn His Leu His His Ser Thr Gln Ala Asn 
    50                  55                  60                  


Ala Ile Leu Ala Ile Glu Gln Phe Glu Gly Leu Leu Gly Thr His Cys 
65                  70                  75                  80  


Ser Pro Asp Leu Leu Phe Phe Leu Cys Ala Met Tyr Ala Pro Ile Cys 
                85                  90                  95      


Thr Ile Asp Phe Gln His Glu Pro Ile Lys Pro Cys Lys Ser Val Cys 
            100                 105                 110         


Glu Arg Ala Arg Gln Gly Cys Glu Pro Ile Leu Ile Lys Tyr Arg His 
        115                 120                 125             


Ser Trp Pro Glu Asn Leu Ala Cys Glu Glu Leu Pro Val Tyr Asp Arg 
    130                 135                 140                 


Gly Val Cys Ile Ser Pro Glu Ala Ile Val Thr Ala Asp Gly Ala Asp 
145                 150                 155                 160 


Phe Pro Met Asp Ser Ser Asn Gly Asn Cys Arg Gly Ala Ser Ser Glu 
                165                 170                 175     


Arg Cys Lys Cys Lys Pro Ile Arg Ala Thr Gln Lys Thr Tyr Phe Arg 
            180                 185                 190         


Asn Asn Tyr Asn Tyr Val Ile Arg Ala Lys Val Lys Glu Ile Lys Thr 
        195                 200                 205             


Lys Cys His Asp Val Thr Ala Val Val Glu Val Lys Glu Ile Leu Lys 
    210                 215                 220                 


Ser Ser Leu Val Asn Ile Pro Arg Asp Thr Val Asn Leu Tyr Thr Ser 
225                 230                 235                 240 


Ser Gly Cys Leu Cys Pro Pro Leu Asn Val Asn Glu Glu Tyr Ile Ile 
                245                 250                 255     


Met Gly Tyr Glu Asp Glu Glu Arg Ser Arg Leu Leu Leu Val Glu Gly 
            260                 265                 270         


Ser Ile Ala Glu Lys Trp Lys Asp Arg Leu Gly Lys Lys Val Lys Arg 
        275                 280                 285             


Trp Asp Met Lys Leu Arg His Leu Gly Leu Ser Lys Ser Asp Ser Ser 
    290                 295                 300                 


Asn Ser Asp Ser Thr Gln Ser Gln Lys Ser Gly Arg Asn Ser Asn Pro 
305                 310                 315                 320 


Arg Gln Ala Arg Asn 
                325 


<210>  3868
<211>  75
<212>  PRT
<213>  homo sapiens

<400>  3868

Met Ala Ser Glu Val Gly His Asn Leu Glu Ser Pro Glu Thr Pro Gly 
1               5                   10                  15      


Gly Gly Gly Trp Thr Arg Val Glu Phe Pro Pro Pro Ala Pro Lys Gly 
            20                  25                  30          


Ala Ala Thr Val Trp Cys Leu Asn Arg Leu Gly Ser Arg Lys Leu Ser 
        35                  40                  45              


Leu Ile Trp Ile Thr Phe Asn Thr Gly Trp Asn Met Lys Ser Arg Leu 
    50                  55                  60                  


Ile Ile Leu Ile Gln Gln Val Ser Cys His His 
65                  70                  75  


<210>  3869
<211>  305
<212>  PRT
<213>  homo sapiens

<400>  3869

Met Gly Tyr Lys Leu Gln Asp Leu Thr Asp Val Gln Ile Met Ala Arg 
1               5                   10                  15      


Leu Gln Glu Glu Ser Leu Arg Gln Asp Tyr Ala Ser Thr Ser Ala Ser 
            20                  25                  30          


Val Ser Arg His Ser Ser Ser Val Ser Leu Ser Ser Gly Lys Lys Gly 
        35                  40                  45              


Thr Cys Ser Asp Gln Glu Tyr Asp Gln Tyr Ser Leu Glu Asp Glu Glu 
    50                  55                  60                  


Glu Phe Asp His Leu Pro Pro Pro Gln Pro Arg Leu Pro Arg Cys Ser 
65                  70                  75                  80  


Pro Phe Gln Arg Gly Ile Pro His Ser Gln Thr Phe Ser Ser Ile Arg 
                85                  90                  95      


Glu Cys Arg Arg Ser Pro Ser Ser Gln Tyr Phe Pro Ser Asn Asn Tyr 
            100                 105                 110         


Gln Gln Gln Gln Tyr Tyr Ser Pro Gln Ala Gln Thr Pro Asp Gln Gln 
        115                 120                 125             


Pro Asn Arg Thr Asn Gly Asp Lys Leu Arg Arg Ser Met Pro Asn Leu 
    130                 135                 140                 


Ala Arg Met Pro Ser Thr Thr Ala Ile Ser Ser Asn Ile Ser Ser Pro 
145                 150                 155                 160 


Val Thr Val Arg Asn Ser Gln Ser Phe Asp Ser Ser Leu His Gly Ala 
                165                 170                 175     


Gly Asn Gly Ile Ser Arg Ile Gln Ser Cys Ile Pro Ser Pro Gly Gln 
            180                 185                 190         


Leu Gln His Arg Val His Ser Val Gly His Phe Pro Val Ser Ile Arg 
        195                 200                 205             


Gln Pro Leu Lys Ala Thr Ala Tyr Val Ser Pro Thr Val Gln Gly Ser 
    210                 215                 220                 


Ser Asn Met Pro Leu Ser Asn Gly Leu Gln Leu Tyr Ser Asn Thr Gly 
225                 230                 235                 240 


Ile Pro Thr Pro Asn Lys Ala Ala Ala Ser Gly Ile Met Gly Arg Ser 
                245                 250                 255     


Ala Leu Pro Arg Pro Ser Leu Ala Ile Asn Gly Ser Asn Leu Pro Arg 
            260                 265                 270         


Ser Lys Ile Ala Gln Pro Val Arg Ser Phe Leu Gln Pro Pro Lys Pro 
        275                 280                 285             


Leu Ser Ser Leu Ser Thr Leu Arg Asp Gly Asn Trp Arg Asp Gly Cys 
    290                 295                 300                 


Tyr 
305 


<210>  3870
<211>  1390
<212>  PRT
<213>  homo sapiens

<400>  3870

Met Val Val Leu Arg Ser Ser Leu Glu Leu His Asn His Ser Ala Ala 
1               5                   10                  15      


Ser Ala Thr Gly Ser Leu Asp Leu Ser Ser Asp Phe Leu Ser Leu Glu 
            20                  25                  30          


His Ile Gly Arg Arg Arg Leu Arg Ser Ala Gly Ala Ala Gln Lys Lys 
        35                  40                  45              


Pro Ala Ala Thr Thr Ala Lys Ala Gly Asp Gly Ser Ser Val Lys Glu 
    50                  55                  60                  


Val Glu Thr Tyr His Arg Thr Arg Ala Leu Arg Ser Leu Arg Lys Asp 
65                  70                  75                  80  


Ala Gln Asn Ser Ser Asp Ser Ser Phe Glu Lys Asn Val Glu Ile Thr 
                85                  90                  95      


Glu Gln Leu Ala Asn Gly Arg His Phe Thr Arg Gln Leu Ala Arg Gln 
            100                 105                 110         


Gln Ala Asp Lys Lys Lys Glu Glu His Arg Glu Asp Lys Val Ile Pro 
        115                 120                 125             


Val Thr Arg Ser Leu Arg Ala Arg Asn Ile Val Gln Ser Thr Glu His 
    130                 135                 140                 


Leu His Glu Asp Asn Gly Asp Val Glu Val Arg Arg Ser Cys Arg Ile 
145                 150                 155                 160 


Arg Ser Arg Tyr Ser Gly Val Asn Gln Ser Met Leu Phe Asp Lys Leu 
                165                 170                 175     


Ile Thr Asn Thr Ala Glu Ala Val Leu Gln Lys Met Asp Asp Met Lys 
            180                 185                 190         


Lys Met Arg Arg Gln Arg Met Arg Glu Leu Glu Asp Leu Gly Val Phe 
        195                 200                 205             


Asn Glu Thr Glu Glu Ser Asn Leu Asn Met Tyr Thr Arg Gly Lys Gln 
    210                 215                 220                 


Lys Asp Ile Gln Arg Thr Asp Glu Glu Thr Thr Asp Asn Gln Glu Gly 
225                 230                 235                 240 


Ser Val Glu Ser Ser Glu Glu Gly Glu Asp Gln Glu His Glu Asp Asp 
                245                 250                 255     


Gly Glu Asp Glu Asp Asp Glu Asp Asp Asp Asp Asp Asp Asp Asp Asp 
            260                 265                 270         


Asp Asp Asp Asp Asp Glu Asp Asp Glu Asp Glu Glu Asp Gly Glu Glu 
        275                 280                 285             


Glu Asn Gln Lys Arg Tyr Tyr Leu Arg Gln Arg Lys Ala Thr Val Tyr 
    290                 295                 300                 


Tyr Gln Ala Pro Leu Glu Lys Pro Arg His Gln Arg Lys Pro Asn Ile 
305                 310                 315                 320 


Phe Tyr Ser Gly Pro Ala Ser Pro Ala Arg Pro Arg Tyr Arg Leu Ser 
                325                 330                 335     


Ser Ala Gly Pro Arg Ser Pro Tyr Cys Lys Arg Met Asn Arg Arg Arg 
            340                 345                 350         


His Ala Ile His Ser Ser Asp Ser Thr Ser Ser Ser Ser Ser Glu Asp 
        355                 360                 365             


Glu Gln His Phe Glu Arg Arg Arg Lys Arg Ser Arg Asn Arg Ala Ile 
    370                 375                 380                 


Asn Arg Cys Leu Pro Leu Asn Phe Arg Lys Asp Glu Leu Lys Gly Ile 
385                 390                 395                 400 


Tyr Lys Asp Arg Met Lys Ile Gly Ala Ser Leu Ala Asp Val Asp Pro 
                405                 410                 415     


Met Gln Leu Asp Ser Ser Val Arg Phe Asp Ser Val Gly Gly Leu Ser 
            420                 425                 430         


Asn His Ile Ala Ala Leu Lys Glu Met Val Val Phe Pro Leu Leu Tyr 
        435                 440                 445             


Pro Glu Val Phe Glu Lys Phe Lys Ile Gln Pro Pro Arg Gly Cys Leu 
    450                 455                 460                 


Phe Tyr Gly Pro Pro Gly Thr Gly Lys Thr Leu Val Ala Arg Ala Leu 
465                 470                 475                 480 


Ala Asn Glu Cys Ser Gln Gly Asp Lys Arg Val Ala Phe Phe Met Arg 
                485                 490                 495     


Lys Gly Ala Asp Cys Leu Ser Lys Trp Val Gly Glu Ser Glu Arg Gln 
            500                 505                 510         


Leu Arg Leu Leu Phe Asp Gln Ala Tyr Gln Met Arg Pro Ser Ile Ile 
        515                 520                 525             


Phe Phe Asp Glu Ile Asp Gly Leu Ala Pro Val Arg Ser Ser Arg Gln 
    530                 535                 540                 


Asp Gln Ile His Ser Ser Ile Val Ser Thr Leu Leu Ala Leu Met Asp 
545                 550                 555                 560 


Gly Leu Asp Ser Arg Gly Glu Ile Val Val Ile Gly Ala Thr Asn Arg 
                565                 570                 575     


Leu Asp Ser Ile Asp Pro Ala Leu Arg Arg Pro Gly Arg Phe Asp Arg 
            580                 585                 590         


Glu Phe Leu Phe Ser Leu Pro Asp Lys Glu Ala Arg Lys Glu Ile Leu 
        595                 600                 605             


Lys Ile His Thr Arg Asp Trp Asn Pro Lys Pro Leu Asp Thr Phe Leu 
    610                 615                 620                 


Glu Glu Leu Ala Glu Asn Cys Val Gly Tyr Cys Gly Ala Asp Ile Lys 
625                 630                 635                 640 


Ser Ile Cys Ala Glu Ala Ala Leu Cys Ala Leu Arg Arg Arg Tyr Pro 
                645                 650                 655     


Gln Ile Tyr Thr Thr Ser Glu Lys Leu Gln Leu Asp Leu Ser Ser Ile 
            660                 665                 670         


Asn Ile Ser Ala Lys Asp Phe Glu Val Ala Met Gln Lys Met Ile Pro 
        675                 680                 685             


Ala Ser Gln Arg Ala Val Thr Ser Pro Gly Gln Ala Leu Ser Thr Val 
    690                 695                 700                 


Val Lys Pro Leu Leu Gln Asn Thr Val Asp Lys Ile Leu Glu Ala Leu 
705                 710                 715                 720 


Gln Arg Val Phe Pro His Ala Glu Phe Arg Thr Asn Lys Thr Leu Asp 
                725                 730                 735     


Ser Asp Ile Ser Cys Pro Leu Leu Glu Ser Asp Leu Ala Tyr Ser Asp 
            740                 745                 750         


Asp Asp Val Pro Ser Val Tyr Glu Asn Gly Leu Ser Gln Lys Ser Ser 
        755                 760                 765             


His Lys Ala Lys Asp Asn Phe Asn Phe Leu His Leu Asn Arg Asn Ala 
    770                 775                 780                 


Cys Tyr Gln Pro Met Ser Phe Arg Pro Arg Ile Leu Ile Val Gly Glu 
785                 790                 795                 800 


Pro Gly Phe Gly Gln Gly Ser His Leu Ala Pro Ala Val Ile His Ala 
                805                 810                 815     


Leu Glu Lys Phe Thr Val Tyr Thr Leu Asp Ile Pro Val Leu Phe Gly 
            820                 825                 830         


Val Ser Thr Thr Ser Pro Glu Glu Thr Cys Ala Gln Val Ile Arg Glu 
        835                 840                 845             


Ala Lys Arg Thr Ala Pro Ser Ile Val Tyr Val Pro His Ile His Val 
    850                 855                 860                 


Trp Trp Glu Ile Val Gly Pro Thr Leu Lys Ala Thr Phe Thr Thr Leu 
865                 870                 875                 880 


Leu Gln Asn Ile Pro Ser Phe Ala Pro Val Leu Leu Leu Ala Thr Ser 
                885                 890                 895     


Asp Lys Pro His Ser Ala Leu Pro Glu Glu Val Gln Glu Leu Phe Ile 
            900                 905                 910         


Arg Asp Tyr Gly Glu Ile Phe Asn Val Gln Leu Pro Asp Lys Glu Glu 
        915                 920                 925             


Arg Thr Lys Phe Phe Glu Asp Leu Ile Leu Lys Gln Ala Ala Lys Pro 
    930                 935                 940                 


Pro Ile Ser Lys Lys Lys Ala Val Leu Gln Ala Leu Glu Val Leu Pro 
945                 950                 955                 960 


Val Ala Pro Pro Pro Glu Pro Arg Ser Leu Thr Ala Glu Glu Val Lys 
                965                 970                 975     


Arg Leu Glu Glu Gln Glu Glu Asp Thr Phe Arg Glu Leu Arg Ile Phe 
            980                 985                 990         


Leu Arg Asn Val Thr His Arg Leu  Ala Ile Asp Lys Arg  Phe Arg Val 
        995                 1000                 1005             


Phe Thr  Lys Pro Val Asp Pro  Asp Glu Val Pro Asp  Tyr Val Thr 
    1010                 1015                 1020             


Val Ile  Lys Gln Pro Met Asp  Leu Ser Ser Val Ile  Ser Lys Ile 
    1025                 1030                 1035             


Asp Leu  His Lys Tyr Leu Thr  Val Lys Asp Tyr Leu  Arg Asp Ile 
    1040                 1045                 1050             


Asp Leu  Ile Cys Ser Asn Ala  Leu Glu Tyr Asn Pro  Asp Arg Asp 
    1055                 1060                 1065             


Pro Gly  Asp Arg Leu Ile Arg  His Arg Ala Cys Ala  Leu Arg Asp 
    1070                 1075                 1080             


Thr Ala  Tyr Ala Ile Ile Lys  Glu Glu Leu Asp Glu  Asp Phe Glu 
    1085                 1090                 1095             


Gln Leu  Cys Glu Glu Ile Gln  Glu Ser Arg Lys Lys  Arg Gly Cys 
    1100                 1105                 1110             


Ser Ser  Ser Lys Tyr Ala Pro  Ser Tyr Tyr His Val  Met Pro Lys 
    1115                 1120                 1125             


Gln Asn  Ser Thr Leu Val Gly  Asp Lys Arg Ser Asp  Pro Glu Gln 
    1130                 1135                 1140             


Asn Glu  Lys Leu Lys Thr Pro  Ser Thr Pro Val Ala  Cys Ser Thr 
    1145                 1150                 1155             


Pro Ala  Gln Leu Lys Arg Lys  Ile Arg Lys Lys Ser  Asn Trp Tyr 
    1160                 1165                 1170             


Leu Gly  Thr Ile Lys Lys Arg  Arg Lys Ile Ser Gln  Ala Lys Asp 
    1175                 1180                 1185             


Asp Ser  Gln Asn Ala Ile Asp  His Lys Ile Glu Ser  Asp Thr Glu 
    1190                 1195                 1200             


Glu Thr  Gln Asp Thr Ser Val  Asp His Asn Glu Thr  Gly Asn Thr 
    1205                 1210                 1215             


Gly Glu  Ser Ser Val Glu Glu  Asn Glu Lys Gln Gln  Asn Ala Ser 
    1220                 1225                 1230             


Glu Ser  Lys Leu Glu Leu Arg  Asn Asn Ser Asn Thr  Cys Asn Ile 
    1235                 1240                 1245             


Glu Asn  Glu Leu Glu Asp Ser  Arg Lys Thr Thr Ala  Cys Thr Glu 
    1250                 1255                 1260             


Leu Arg  Asp Lys Ile Ala Cys  Asn Gly Asp Ala Ser  Ser Ser Gln 
    1265                 1270                 1275             


Ile Ile  His Ile Ser Asp Glu  Asn Glu Gly Lys Glu  Met Cys Val 
    1280                 1285                 1290             


Leu Arg  Met Thr Arg Ala Arg  Arg Ser Gln Val Glu  Gln Gln Gln 
    1295                 1300                 1305             


Leu Ile  Thr Val Glu Lys Ala  Leu Ala Ile Leu Ser  Gln Pro Thr 
    1310                 1315                 1320             


Pro Ser  Leu Val Val Asp His  Glu Arg Leu Lys Asn  Leu Leu Lys 
    1325                 1330                 1335             


Thr Val  Val Lys Lys Ser Gln  Asn Tyr Asn Ile Phe  Gln Leu Glu 
    1340                 1345                 1350             


Asn Leu  Tyr Ala Val Ile Ser  Gln Cys Ile Tyr Arg  His Arg Lys 
    1355                 1360                 1365             


Asp His  Asp Lys Thr Ser Leu  Ile Gln Lys Met Glu  Gln Glu Val 
    1370                 1375                 1380             


Glu Asn  Phe Ser Cys Ser Arg  
    1385                 1390 


<210>  3871
<211>  505
<212>  PRT
<213>  homo sapiens

<400>  3871

Met Lys Phe Lys Leu His Val Asn Ser Ala Arg Gln Tyr Lys Asp Leu 
1               5                   10                  15      


Trp Asn Met Ser Asp Asp Lys Pro Phe Leu Cys Thr Ala Pro Gly Cys 
            20                  25                  30          


Gly Gln Arg Phe Thr Asn Glu Asp His Leu Ala Val His Lys His Lys 
        35                  40                  45              


His Glu Met Thr Leu Lys Phe Gly Pro Ala Arg Asn Asp Ser Val Ile 
    50                  55                  60                  


Val Ala Asp Gln Thr Pro Thr Pro Thr Arg Phe Leu Lys Asn Cys Glu 
65                  70                  75                  80  


Glu Val Gly Leu Phe Asn Glu Leu Ala Ser Pro Phe Glu Asn Glu Phe 
                85                  90                  95      


Lys Lys Ala Ser Glu Asp Asp Ile Lys Lys Met Pro Leu Asp Leu Ser 
            100                 105                 110         


Pro Leu Ala Thr Pro Ile Ile Arg Ser Lys Ile Glu Glu Pro Ser Val 
        115                 120                 125             


Val Glu Thr Thr His Gln Asp Ser Pro Leu Pro His Pro Glu Ser Thr 
    130                 135                 140                 


Thr Ser Asp Glu Lys Glu Val Pro Leu Ala Gln Thr Ala Gln Pro Thr 
145                 150                 155                 160 


Ser Ala Ile Val Arg Pro Ala Ser Leu Gln Val Pro Asn Val Leu Leu 
                165                 170                 175     


Thr Ser Ser Asp Ser Ser Val Ile Ile Gln Gln Ala Val Pro Ser Pro 
            180                 185                 190         


Thr Ser Ser Thr Val Ile Thr Gln Ala Pro Ser Ser Asn Arg Pro Ile 
        195                 200                 205             


Val Pro Val Pro Gly Pro Phe Pro Leu Leu Leu His Leu Pro Asn Gly 
    210                 215                 220                 


Gln Thr Met Pro Val Ala Ile Pro Ala Ser Ile Thr Ser Ser Asn Val 
225                 230                 235                 240 


His Val Pro Ala Ala Val Pro Leu Val Arg Pro Val Thr Met Val Pro 
                245                 250                 255     


Ser Val Pro Gly Ile Pro Gly Pro Ser Ser Pro Gln Pro Val Gln Ser 
            260                 265                 270         


Glu Ala Lys Met Arg Leu Lys Ala Ala Leu Thr Gln Gln His Pro Pro 
        275                 280                 285             


Val Thr Asn Gly Asp Thr Val Lys Gly His Gly Ser Gly Leu Val Arg 
    290                 295                 300                 


Thr Gln Ser Glu Glu Ser Arg Pro Gln Ser Leu Gln Gln Pro Ala Thr 
305                 310                 315                 320 


Ser Thr Thr Glu Thr Pro Ala Ser Pro Ala His Thr Thr Pro Gln Thr 
                325                 330                 335     


Gln Ser Thr Ser Gly Arg Arg Arg Arg Ala Ala Asn Glu Asp Pro Asp 
            340                 345                 350         


Glu Lys Arg Arg Lys Phe Leu Glu Arg Asn Arg Ala Ala Ala Ser Arg 
        355                 360                 365             


Cys Arg Gln Lys Arg Lys Val Trp Val Gln Ser Leu Glu Lys Lys Ala 
    370                 375                 380                 


Glu Asp Leu Ser Ser Leu Asn Gly Gln Leu Gln Ser Glu Val Thr Leu 
385                 390                 395                 400 


Leu Arg Asn Glu Val Ala Gln Leu Lys Gln Leu Leu Leu Ala His Lys 
                405                 410                 415     


Asp Cys Pro Val Thr Ala Met Gln Lys Lys Ser Gly Tyr His Thr Ala 
            420                 425                 430         


Asp Lys Asp Asp Ser Ser Glu Asp Ile Ser Val Pro Ser Ser Pro His 
        435                 440                 445             


Thr Glu Ala Ile Gln His Ser Ser Val Ser Thr Ser Asn Gly Val Ser 
    450                 455                 460                 


Ser Thr Ser Lys Ala Glu Ala Val Ala Thr Ser Val Leu Thr Gln Met 
465                 470                 475                 480 


Ala Asp Gln Ser Thr Glu Pro Ala Leu Ser Gln Ile Val Met Ala Pro 
                485                 490                 495     


Ser Ser Gln Ser Gln Pro Ser Gly Ser 
            500                 505 


<210>  3872
<211>  1375
<212>  PRT
<213>  homo sapiens

<400>  3872

Met Glu Gly Asp Arg Val Ala Gly Arg Pro Val Leu Ser Ser Leu Pro 
1               5                   10                  15      


Val Leu Leu Leu Leu Pro Leu Leu Met Leu Arg Ala Ala Ala Leu His 
            20                  25                  30          


Pro Asp Glu Leu Phe Pro His Gly Glu Ser Trp Gly Asp Gln Leu Leu 
        35                  40                  45              


Gln Glu Gly Asp Asp Glu Ser Ser Ala Val Val Lys Leu Ala Asn Pro 
    50                  55                  60                  


Leu His Phe Tyr Glu Ala Arg Phe Ser Asn Leu Tyr Val Gly Thr Asn 
65                  70                  75                  80  


Gly Ile Ile Ser Thr Gln Asp Phe Pro Arg Glu Thr Gln Tyr Val Asp 
                85                  90                  95      


Tyr Asp Phe Pro Thr Asp Phe Pro Ala Ile Ala Pro Phe Leu Ala Asp 
            100                 105                 110         


Ile Asp Thr Ser His Gly Arg Gly Arg Val Leu Tyr Arg Glu Asp Thr 
        115                 120                 125             


Ser Pro Ala Val Leu Gly Leu Ala Ala Arg Tyr Val Arg Ala Gly Phe 
    130                 135                 140                 


Pro Arg Ser Ala Arg Phe Thr Pro Thr His Ala Phe Leu Ala Thr Trp 
145                 150                 155                 160 


Glu Gln Val Gly Ala Tyr Glu Glu Val Lys Arg Gly Ala Leu Pro Ser 
                165                 170                 175     


Gly Glu Leu Asn Thr Phe Gln Ala Val Leu Ala Ser Asp Gly Ser Asp 
            180                 185                 190         


Ser Tyr Ala Leu Phe Leu Tyr Pro Ala Asn Gly Leu Gln Phe Leu Gly 
        195                 200                 205             


Thr Arg Pro Lys Glu Ser Tyr Asn Val Gln Leu Gln Leu Pro Ala Arg 
    210                 215                 220                 


Val Gly Phe Cys Arg Gly Glu Ala Asp Asp Leu Lys Ser Glu Gly Pro 
225                 230                 235                 240 


Tyr Phe Ser Leu Thr Ser Thr Glu Gln Ser Val Lys Asn Leu Tyr Gln 
                245                 250                 255     


Leu Ser Asn Leu Gly Ile Pro Gly Val Trp Ala Phe His Ile Gly Ser 
            260                 265                 270         


Thr Ser Pro Leu Asp Asn Val Arg Pro Ala Ala Val Gly Asp Leu Ser 
        275                 280                 285             


Ala Ala His Ser Ser Val Pro Leu Gly Arg Ser Phe Ser His Ala Thr 
    290                 295                 300                 


Ala Leu Glu Ser Asp Tyr Asn Glu Asp Asn Leu Asp Tyr Tyr Asp Val 
305                 310                 315                 320 


Asn Glu Glu Glu Ala Glu Tyr Leu Pro Gly Glu Pro Glu Glu Ala Leu 
                325                 330                 335     


Asn Gly His Ser Ser Ile Asp Val Ser Phe Gln Ser Lys Val Asp Thr 
            340                 345                 350         


Lys Pro Leu Glu Glu Ser Ser Thr Leu Asp Pro His Thr Lys Glu Gly 
        355                 360                 365             


Thr Ser Leu Gly Glu Val Gly Gly Pro Asp Leu Lys Gly Gln Val Glu 
    370                 375                 380                 


Pro Trp Asp Glu Arg Glu Thr Arg Ser Pro Ala Pro Pro Glu Val Asp 
385                 390                 395                 400 


Arg Asp Ser Leu Ala Pro Ser Trp Glu Thr Pro Pro Pro Tyr Pro Glu 
                405                 410                 415     


Asn Gly Ser Ile Gln Pro Tyr Pro Asp Gly Gly Pro Val Pro Ser Glu 
            420                 425                 430         


Met Asp Val Pro Pro Ala His Pro Glu Glu Glu Ile Val Leu Arg Ser 
        435                 440                 445             


Tyr Pro Ala Ser Gly His Thr Thr Pro Leu Ser Arg Gly Thr Tyr Glu 
    450                 455                 460                 


Val Gly Leu Glu Asp Asn Ile Gly Ser Asn Thr Glu Val Phe Thr Tyr 
465                 470                 475                 480 


Asn Ala Ala Asn Lys Glu Thr Cys Glu His Asn His Arg Gln Cys Ser 
                485                 490                 495     


Arg His Ala Phe Cys Thr Asp Tyr Ala Thr Gly Phe Cys Cys His Cys 
            500                 505                 510         


Gln Ser Lys Phe Tyr Gly Asn Gly Lys His Cys Leu Pro Glu Gly Ala 
        515                 520                 525             


Pro His Arg Val Asn Gly Lys Val Ser Gly His Leu His Val Gly His 
    530                 535                 540                 


Thr Pro Val His Phe Thr Asp Val Asp Leu His Ala Tyr Ile Val Gly 
545                 550                 555                 560 


Asn Asp Gly Arg Ala Tyr Thr Ala Ile Ser His Ile Pro Gln Pro Ala 
                565                 570                 575     


Ala Gln Ala Leu Leu Pro Leu Thr Pro Ile Gly Gly Leu Phe Gly Trp 
            580                 585                 590         


Leu Phe Ala Leu Glu Lys Pro Gly Ser Glu Asn Gly Phe Ser Leu Ala 
        595                 600                 605             


Gly Ala Ala Phe Thr His Asp Met Glu Val Thr Phe Tyr Pro Gly Glu 
    610                 615                 620                 


Glu Thr Val Arg Ile Thr Gln Thr Ala Glu Gly Leu Asp Pro Glu Asn 
625                 630                 635                 640 


Tyr Leu Ser Ile Lys Thr Asn Ile Gln Gly Gln Val Pro Tyr Val Ser 
                645                 650                 655     


Ala Asn Phe Thr Ala His Ile Ser Pro Tyr Lys Glu Leu Tyr His Tyr 
            660                 665                 670         


Ser Asp Ser Thr Val Thr Ser Thr Ser Ser Arg Asp Tyr Ser Leu Thr 
        675                 680                 685             


Phe Gly Ala Ile Asn Gln Thr Trp Ser Tyr Arg Ile His Gln Asn Ile 
    690                 695                 700                 


Thr Tyr Gln Val Cys Arg His Ala Pro Arg His Pro Ser Phe Pro Thr 
705                 710                 715                 720 


Thr Gln Gln Leu Asn Val Asp Arg Val Phe Ala Leu Tyr Asn Asp Glu 
                725                 730                 735     


Glu Arg Val Leu Arg Phe Ala Val Thr Asn Gln Ile Gly Pro Val Lys 
            740                 745                 750         


Glu Asp Ser Asp Pro Thr Pro Gly Asn Pro Cys Tyr Asp Gly Ser His 
        755                 760                 765             


Met Cys Asp Thr Thr Ala Arg Cys His Pro Gly Thr Gly Val Asp Tyr 
    770                 775                 780                 


Thr Cys Glu Cys Ala Ser Gly Tyr Gln Gly Asp Gly Arg Asn Cys Val 
785                 790                 795                 800 


Asp Glu Asn Glu Cys Ala Thr Gly Phe His Arg Cys Gly Pro Asn Ser 
                805                 810                 815     


Val Cys Ile Asn Leu Pro Gly Ser Tyr Arg Cys Glu Cys Arg Ser Gly 
            820                 825                 830         


Tyr Glu Phe Ala Asp Asp Arg His Thr Cys Ile Leu Ile Thr Pro Pro 
        835                 840                 845             


Ala Asn Pro Cys Glu Asp Gly Ser His Thr Cys Ala Pro Ala Gly Gln 
    850                 855                 860                 


Ala Arg Cys Val His His Gly Gly Ser Thr Phe Ser Cys Ala Cys Leu 
865                 870                 875                 880 


Pro Gly Tyr Ala Gly Asp Gly His Gln Cys Thr Asp Val Asp Glu Cys 
                885                 890                 895     


Ser Glu Asn Arg Cys His Pro Ala Ala Thr Cys Tyr Asn Thr Pro Gly 
            900                 905                 910         


Ser Phe Ser Cys Arg Cys Gln Pro Gly Tyr Tyr Gly Asp Gly Phe Gln 
        915                 920                 925             


Cys Ile Pro Asp Ser Thr Ser Ser Leu Thr Pro Cys Glu Gln Gln Gln 
    930                 935                 940                 


Arg His Ala Gln Ala Gln Tyr Ala Tyr Pro Gly Ala Arg Phe His Ile 
945                 950                 955                 960 


Pro Gln Cys Asp Glu Gln Gly Asn Phe Leu Pro Leu Gln Cys His Gly 
                965                 970                 975     


Ser Thr Gly Phe Cys Trp Cys Val Asp Pro Asp Gly His Glu Val Pro 
            980                 985                 990         


Gly Thr Gln Thr Pro Pro Gly Ser  Thr Pro Pro His Cys  Gly Pro Ser 
        995                 1000                 1005             


Pro Glu  Pro Thr Gln Arg Pro  Pro Thr Ile Cys Glu  Arg Trp Arg 
    1010                 1015                 1020             


Glu Asn  Leu Leu Glu His Tyr  Gly Gly Thr Pro Arg  Asp Asp Gln 
    1025                 1030                 1035             


Tyr Val  Pro Gln Cys Asp Asp  Leu Gly His Phe Ile  Pro Leu Gln 
    1040                 1045                 1050             


Cys His  Gly Lys Ser Asp Phe  Cys Trp Cys Val Asp  Lys Asp Gly 
    1055                 1060                 1065             


Arg Glu  Val Gln Gly Thr Arg  Ser Gln Pro Gly Thr  Thr Pro Ala 
    1070                 1075                 1080             


Cys Ile  Pro Thr Val Ala Pro  Pro Met Val Arg Pro  Thr Pro Arg 
    1085                 1090                 1095             


Pro Asp  Val Thr Pro Pro Ser  Val Gly Thr Phe Leu  Leu Tyr Thr 
    1100                 1105                 1110             


Gln Gly  Gln Gln Ile Gly Tyr  Leu Pro Leu Asn Gly  Thr Arg Leu 
    1115                 1120                 1125             


Gln Lys  Asp Ala Ala Lys Thr  Leu Leu Ser Leu His  Gly Ser Ile 
    1130                 1135                 1140             


Ile Val  Gly Ile Asp Tyr Asp  Cys Arg Glu Arg Met  Val Tyr Trp 
    1145                 1150                 1155             


Thr Asp  Val Ala Gly Arg Thr  Ile Ser Arg Ala Gly  Leu Glu Leu 
    1160                 1165                 1170             


Gly Ala  Glu Pro Glu Thr Ile  Val Asn Ser Gly Leu  Ile Ser Pro 
    1175                 1180                 1185             


Glu Gly  Leu Ala Ile Asp His  Ile Arg Arg Thr Met  Tyr Trp Thr 
    1190                 1195                 1200             


Asp Ser  Val Leu Asp Lys Ile  Glu Ser Ala Leu Leu  Asp Gly Ser 
    1205                 1210                 1215             


Glu Arg  Lys Val Leu Phe Tyr  Thr Asp Leu Val Asn  Pro Arg Ala 
    1220                 1225                 1230             


Ile Ala  Val Asp Pro Ile Arg  Gly Asn Leu Tyr Trp  Thr Asp Trp 
    1235                 1240                 1245             


Asn Arg  Glu Ala Pro Lys Ile  Glu Thr Ser Ser Leu  Asp Gly Glu 
    1250                 1255                 1260             


Asn Arg  Arg Ile Leu Ile Asn  Thr Asp Ile Gly Leu  Pro Asn Gly 
    1265                 1270                 1275             


Leu Thr  Phe Asp Pro Phe Ser  Lys Leu Leu Cys Trp  Ala Asp Ala 
    1280                 1285                 1290             


Gly Thr  Lys Lys Leu Glu Cys  Thr Leu Pro Asp Gly  Thr Gly Arg 
    1295                 1300                 1305             


Arg Val  Ile Gln Asn Asn Leu  Lys Tyr Pro Phe Ser  Ile Val Ser 
    1310                 1315                 1320             


Tyr Ala  Asp His Phe Tyr His  Thr Asp Trp Arg Arg  Asp Gly Val 
    1325                 1330                 1335             


Val Ser  Val Asn Lys His Ser  Gly Gln Phe Thr Asp  Glu Tyr Leu 
    1340                 1345                 1350             


Pro Glu  Gln Arg Ser His Leu  Tyr Gly Ile Thr Ala  Val Tyr Pro 
    1355                 1360                 1365             


Tyr Cys  Pro Thr Gly Arg Lys  
    1370                 1375 


<210>  3873
<211>  235
<212>  PRT
<213>  homo sapiens

<400>  3873

Met Gly Ile Gly Lys Ser Lys Ile Asn Ser Cys Pro Leu Ser Leu Ser 
1               5                   10                  15      


Trp Gly Lys Arg His Ser Val Asp Thr Ser Pro Gly Tyr His Glu Ser 
            20                  25                  30          


Asp Ser Lys Lys Ser Glu Asp Leu Ser Leu Cys Asn Val Ala Glu His 
        35                  40                  45              


Ser Asn Thr Thr Glu Gly Pro Thr Gly Lys Gln Glu Gly Ala Gln Ser 
    50                  55                  60                  


Val Glu Glu Met Phe Glu Glu Glu Ala Glu Glu Glu Val Phe Leu Lys 
65                  70                  75                  80  


Phe Val Ile Leu His Ala Glu Asp Asp Thr Asp Glu Ala Leu Arg Val 
                85                  90                  95      


Gln Asn Leu Leu Gln Asp Asp Phe Gly Ile Lys Pro Gly Ile Ile Phe 
            100                 105                 110         


Ala Glu Met Pro Cys Gly Arg Gln His Leu Gln Asn Leu Asp Asp Ala 
        115                 120                 125             


Val Asn Gly Ser Ala Trp Thr Ile Leu Leu Leu Thr Glu Asn Phe Leu 
    130                 135                 140                 


Arg Asp Thr Trp Cys Asn Phe Gln Phe Tyr Thr Ser Leu Met Asn Ser 
145                 150                 155                 160 


Val Asn Arg Gln His Lys Tyr Asn Ser Val Ile Pro Met Arg Pro Leu 
                165                 170                 175     


Asn Asn Pro Leu Pro Arg Glu Arg Thr Pro Phe Ala Leu Gln Thr Ile 
            180                 185                 190         


Asn Ala Leu Glu Glu Glu Ser Arg Gly Phe Pro Thr Gln Val Glu Arg 
        195                 200                 205             


Ile Phe Gln Glu Ser Val Tyr Lys Thr Gln Gln Thr Ile Trp Lys Glu 
    210                 215                 220                 


Thr Arg Asn Met Val Gln Arg Gln Phe Ile Ala 
225                 230                 235 


<210>  3874
<211>  188
<212>  PRT
<213>  homo sapiens

<400>  3874

Met Pro Arg Pro Gly Ser Ala Gln Arg Trp Ala Ala Val Ala Gly Arg 
1               5                   10                  15      


Trp Gly Cys Arg Leu Leu Ala Leu Leu Leu Leu Val Pro Gly Pro Gly 
            20                  25                  30          


Gly Ala Ser Glu Ile Thr Phe Glu Leu Pro Asp Asn Ala Lys Gln Cys 
        35                  40                  45              


Phe Tyr Glu Asp Ile Ala Gln Gly Thr Lys Cys Thr Leu Glu Phe Gln 
    50                  55                  60                  


Val Ile Thr Gly Gly His Tyr Asp Val Asp Cys Arg Leu Glu Asp Pro 
65                  70                  75                  80  


Asp Gly Lys Val Leu Tyr Lys Glu Met Lys Lys Gln Tyr Asp Ser Phe 
                85                  90                  95      


Thr Phe Thr Ala Ser Lys Asn Gly Thr Tyr Lys Phe Cys Phe Ser Asn 
            100                 105                 110         


Glu Phe Ser Thr Phe Thr His Lys Thr Val Tyr Phe Asp Phe Gln Val 
        115                 120                 125             


Gly Glu Asp Pro Pro Leu Phe Pro Ser Glu Asn Arg Val Ser Ala Leu 
    130                 135                 140                 


Thr Gln Met Glu Ser Ala Cys Val Ser Ile His Glu Ala Leu Lys Ser 
145                 150                 155                 160 


Val Ile Asp Tyr Gln Thr His Phe Arg Leu Arg Glu Ala Gln Gly Arg 
                165                 170                 175     


Ser Arg Ala Glu Asp Leu Asn Thr Arg Val Ala Tyr 
            180                 185             


<210>  3875
<211>  181
<212>  PRT
<213>  homo sapiens

<400>  3875

Met Met Leu Gln His Pro Gly Gln Val Ser Ala Ser Glu Val Ser Ala 
1               5                   10                  15      


Ser Ala Ile Val Pro Cys Leu Ser Pro Pro Gly Ser Leu Val Phe Glu 
            20                  25                  30          


Asp Phe Ala Asn Leu Thr Pro Phe Val Lys Glu Glu Leu Arg Phe Ala 
        35                  40                  45              


Ile Gln Asn Lys His Leu Cys His Arg Met Ser Ser Ala Leu Glu Ser 
    50                  55                  60                  


Val Thr Val Ser Asp Arg Pro Leu Gly Val Ser Ile Thr Lys Ala Glu 
65                  70                  75                  80  


Val Ala Pro Glu Glu Asp Glu Arg Lys Lys Arg Arg Arg Glu Arg Asn 
                85                  90                  95      


Lys Ile Ala Ala Ala Lys Cys Arg Asn Lys Lys Lys Glu Lys Thr Glu 
            100                 105                 110         


Cys Leu Gln Lys Glu Ser Glu Lys Leu Glu Ser Val Asn Ala Glu Leu 
        115                 120                 125             


Lys Ala Gln Ile Glu Glu Leu Lys Asn Glu Lys Gln His Leu Ile Tyr 
    130                 135                 140                 


Met Leu Asn Leu His Arg Pro Thr Cys Ile Val Arg Ala Gln Asn Gly 
145                 150                 155                 160 


Arg Thr Pro Glu Asp Glu Arg Asn Leu Phe Ile Gln Gln Ile Lys Glu 
                165                 170                 175     


Gly Thr Leu Gln Ser 
            180     


<210>  3876
<211>  462
<212>  PRT
<213>  homo sapiens

<400>  3876

Met Gly Gly Ala Glu Ala Glu Pro Trp Gly Arg Ala Pro Gly Pro Ala 
1               5                   10                  15      


Ile Gly Gly Arg Arg Ala Gly Asp Ser Cys Pro Gly Trp Arg Arg Arg 
            20                  25                  30          


Ser Arg Ser Arg Gly Arg Gly Gln Arg Leu Ser His Gly Pro Arg Arg 
        35                  40                  45              


Arg Pro Gln Leu Leu Thr Ala Ala Pro Pro Leu Gln Ala Arg Gly Ala 
    50                  55                  60                  


Phe Arg Ser Phe Pro His Ser Trp Gly Glu Asp Phe Leu Ala Ser Leu 
65                  70                  75                  80  


Met Phe Lys Ile Gln Leu Glu Pro Leu Lys Leu Arg Ala Trp Thr Leu 
                85                  90                  95      


Asn Gly Phe Val Lys Phe Arg Asn Lys Glu Thr Ser Ala Gly Pro Val 
            100                 105                 110         


Ala Val Met Gly Lys Asp Tyr Tyr Lys Ile Leu Gly Ile Pro Ser Gly 
        115                 120                 125             


Ala Asn Glu Asp Glu Ile Lys Lys Ala Tyr Arg Lys Met Ala Leu Lys 
    130                 135                 140                 


Tyr His Pro Asp Lys Asn Lys Glu Pro Asn Ala Glu Glu Lys Phe Lys 
145                 150                 155                 160 


Glu Ile Ala Glu Ala Tyr Asp Val Leu Ser Asp Pro Lys Lys Arg Gly 
                165                 170                 175     


Leu Tyr Asp Gln Tyr Gly Glu Glu Gly Leu Lys Thr Gly Gly Gly Thr 
            180                 185                 190         


Ser Gly Gly Ser Ser Gly Ser Phe His Tyr Thr Phe His Gly Asp Pro 
        195                 200                 205             


His Ala Thr Phe Ala Ser Phe Phe Gly Gly Ser Asn Pro Phe Asp Ile 
    210                 215                 220                 


Phe Phe Ala Ser Ser Arg Ser Thr Arg Pro Phe Ser Gly Phe Asp Pro 
225                 230                 235                 240 


Asp Asp Met Asp Val Asp Glu Asp Glu Asp Pro Phe Gly Ala Phe Gly 
                245                 250                 255     


Arg Phe Gly Phe Asn Gly Leu Ser Arg Gly Pro Arg Arg Ala Pro Glu 
            260                 265                 270         


Pro Leu Tyr Pro Arg Arg Lys Val Gln Asp Pro Pro Val Val His Glu 
        275                 280                 285             


Leu Arg Val Ser Leu Glu Glu Ile Tyr His Gly Ser Thr Lys Arg Met 
    290                 295                 300                 


Lys Ile Thr Arg Arg Arg Leu Asn Pro Asp Gly Arg Thr Val Arg Thr 
305                 310                 315                 320 


Glu Asp Lys Ile Leu His Ile Val Ile Lys Arg Gly Trp Lys Glu Gly 
                325                 330                 335     


Thr Lys Ile Thr Phe Pro Lys Glu Gly Asp Ala Thr Pro Asp Asn Ile 
            340                 345                 350         


Pro Ala Asp Ile Val Phe Val Leu Lys Asp Lys Pro His Ala His Phe 
        355                 360                 365             


Arg Arg Asp Gly Thr Asn Val Leu Tyr Ser Ala Leu Ile Ser Leu Lys 
    370                 375                 380                 


Glu Ala Leu Cys Gly Cys Thr Val Asn Ile Pro Thr Ile Asp Gly Arg 
385                 390                 395                 400 


Val Ile Pro Leu Pro Cys Asn Asp Val Ile Lys Pro Gly Thr Val Lys 
                405                 410                 415     


Arg Leu Arg Gly Glu Gly Leu Pro Phe Pro Lys Val Pro Thr Gln Arg 
            420                 425                 430         


Gly Asp Leu Ile Val Glu Phe Lys Val Arg Phe Pro Asp Arg Leu Thr 
        435                 440                 445             


Pro Gln Thr Arg Gln Ile Leu Lys Gln His Leu Pro Cys Ser 
    450                 455                 460         


<210>  3877
<211>  121
<212>  PRT
<213>  homo sapiens

<400>  3877

Met Glu Ala Glu Val Asp Lys Leu Glu Leu Met Phe Gln Lys Ala Glu 
1               5                   10                  15      


Ser Asp Leu Asp Tyr Ile Gln Tyr Arg Leu Glu Tyr Glu Ile Lys Thr 
            20                  25                  30          


Asn His Pro Asp Ser Ala Ser Glu Lys Asn Pro Val Thr Leu Leu Lys 
        35                  40                  45              


Glu Leu Ser Val Ile Lys Ser Arg Tyr Gln Thr Leu Tyr Ala Arg Phe 
    50                  55                  60                  


Lys Pro Val Ala Val Glu Gln Lys Glu Ser Lys Ser Arg Ile Cys Ala 
65                  70                  75                  80  


Thr Val Lys Lys Thr Met Asn Met Ile Gln Lys Leu Gln Lys Gln Thr 
                85                  90                  95      


Asp Leu Glu Leu Ser Pro Leu Thr Lys Glu Glu Lys Thr Ala Ala Glu 
            100                 105                 110         


Gln Phe Lys Phe His Met Pro Asp Leu 
        115                 120     


<210>  3878
<211>  340
<212>  PRT
<213>  homo sapiens

<400>  3878

Met Glu Thr Ser Ala Leu Lys Gln Gln Glu Gln Pro Ala Ala Thr Lys 
1               5                   10                  15      


Ile Arg Asn Leu Pro Trp Val Glu Lys Tyr Arg Pro Gln Thr Leu Asn 
            20                  25                  30          


Asp Leu Ile Ser His Gln Asp Ile Leu Ser Thr Ile Gln Lys Phe Ile 
        35                  40                  45              


Asn Glu Asp Arg Leu Pro His Leu Leu Leu Tyr Gly Pro Pro Gly Thr 
    50                  55                  60                  


Gly Lys Thr Ser Thr Ile Leu Ala Cys Ala Lys Gln Leu Tyr Lys Asp 
65                  70                  75                  80  


Lys Glu Phe Gly Ser Met Val Leu Glu Leu Asn Ala Ser Asp Asp Arg 
                85                  90                  95      


Gly Ile Asp Ile Ile Arg Gly Pro Ile Leu Ser Phe Ala Ser Thr Arg 
            100                 105                 110         


Thr Ile Phe Lys Lys Gly Phe Lys Leu Val Ile Leu Asp Glu Ala Asp 
        115                 120                 125             


Ala Met Thr Gln Asp Ala Gln Asn Ala Leu Arg Arg Val Ile Glu Lys 
    130                 135                 140                 


Phe Thr Glu Asn Thr Arg Phe Cys Leu Ile Cys Asn Tyr Leu Ser Lys 
145                 150                 155                 160 


Ile Ile Pro Ala Leu Gln Ser Arg Cys Thr Arg Phe Arg Phe Gly Pro 
                165                 170                 175     


Leu Thr Pro Glu Leu Met Val Pro Arg Leu Glu His Val Val Glu Glu 
            180                 185                 190         


Glu Lys Val Asp Ile Ser Glu Asp Gly Met Lys Ala Leu Val Thr Leu 
        195                 200                 205             


Ser Ser Gly Asp Met Arg Arg Ala Leu Asn Ile Leu Gln Ser Thr Asn 
    210                 215                 220                 


Met Ala Phe Gly Lys Val Thr Glu Glu Thr Val Tyr Thr Cys Thr Gly 
225                 230                 235                 240 


His Pro Leu Lys Ser Asp Ile Ala Asn Ile Leu Asp Trp Met Leu Asn 
                245                 250                 255     


Gln Asp Phe Thr Thr Ala Tyr Arg Asn Ile Thr Glu Leu Lys Thr Leu 
            260                 265                 270         


Lys Gly Leu Ala Leu His Asp Ile Leu Thr Glu Ile His Leu Phe Val 
        275                 280                 285             


His Arg Val Asp Phe Pro Ser Ser Val Arg Ile His Leu Leu Thr Lys 
    290                 295                 300                 


Met Ala Asp Ile Glu Tyr Arg Leu Ser Val Gly Thr Asn Glu Lys Ile 
305                 310                 315                 320 


Gln Leu Ser Ser Leu Ile Ala Ala Phe Gln Val Thr Arg Asp Leu Ile 
                325                 330                 335     


Val Ala Glu Ala 
            340 


<210>  3879
<211>  319
<212>  PRT
<213>  homo sapiens

<400>  3879

Met Val Glu Lys Tyr Arg Pro Gln Thr Leu Asn Asp Leu Ile Ser His 
1               5                   10                  15      


Gln Asp Ile Leu Ser Thr Ile Gln Lys Phe Ile Asn Glu Asp Arg Leu 
            20                  25                  30          


Pro His Leu Leu Leu Tyr Gly Pro Pro Gly Thr Gly Lys Thr Ser Thr 
        35                  40                  45              


Ile Leu Ala Cys Ala Lys Gln Leu Tyr Lys Asp Lys Glu Phe Gly Ser 
    50                  55                  60                  


Met Val Leu Glu Leu Asn Ala Ser Asp Asp Arg Gly Ile Asp Ile Ile 
65                  70                  75                  80  


Arg Gly Pro Ile Leu Ser Phe Ala Ser Thr Arg Thr Ile Phe Lys Lys 
                85                  90                  95      


Gly Phe Lys Leu Val Ile Leu Asp Glu Ala Asp Ala Met Thr Gln Asp 
            100                 105                 110         


Ala Gln Asn Ala Leu Arg Arg Val Ile Glu Lys Phe Thr Glu Asn Thr 
        115                 120                 125             


Arg Phe Cys Leu Ile Cys Asn Tyr Leu Ser Lys Ile Ile Pro Ala Leu 
    130                 135                 140                 


Gln Ser Arg Cys Thr Arg Phe Arg Phe Gly Pro Leu Thr Pro Glu Leu 
145                 150                 155                 160 


Met Val Pro Arg Leu Glu His Val Val Glu Glu Glu Lys Val Asp Ile 
                165                 170                 175     


Ser Glu Asp Gly Met Lys Ala Leu Val Thr Leu Ser Ser Gly Asp Met 
            180                 185                 190         


Arg Arg Ala Leu Asn Ile Leu Gln Ser Thr Asn Met Ala Phe Gly Lys 
        195                 200                 205             


Val Thr Glu Glu Thr Val Tyr Thr Cys Thr Gly His Pro Leu Lys Ser 
    210                 215                 220                 


Asp Ile Ala Asn Ile Leu Asp Trp Met Leu Asn Gln Asp Phe Thr Thr 
225                 230                 235                 240 


Ala Tyr Arg Asn Ile Thr Glu Leu Lys Thr Leu Lys Gly Leu Ala Leu 
                245                 250                 255     


His Asp Ile Leu Thr Glu Ile His Leu Phe Val His Arg Val Asp Phe 
            260                 265                 270         


Pro Ser Ser Val Arg Ile His Leu Leu Thr Lys Met Ala Asp Ile Glu 
        275                 280                 285             


Tyr Arg Leu Ser Val Gly Thr Asn Glu Lys Ile Gln Leu Ser Ser Leu 
    290                 295                 300                 


Ile Ala Ala Phe Gln Val Thr Arg Asp Leu Ile Val Ala Glu Ala 
305                 310                 315                 


<210>  3880
<211>  181
<212>  PRT
<213>  homo sapiens

<400>  3880

Met Met Leu Gln His Pro Gly Gln Val Ser Ala Ser Glu Val Ser Ala 
1               5                   10                  15      


Ser Ala Ile Val Pro Cys Leu Ser Pro Pro Gly Ser Leu Val Phe Glu 
            20                  25                  30          


Asp Phe Ala Asn Leu Thr Pro Phe Val Lys Glu Glu Leu Arg Phe Ala 
        35                  40                  45              


Ile Gln Asn Lys His Leu Cys His Arg Met Ser Ser Ala Leu Glu Ser 
    50                  55                  60                  


Val Thr Val Ser Asp Arg Pro Leu Gly Val Ser Ile Thr Lys Ala Glu 
65                  70                  75                  80  


Val Ala Pro Glu Glu Asp Glu Arg Lys Lys Arg Arg Arg Glu Arg Asn 
                85                  90                  95      


Lys Ile Ala Ala Ala Lys Cys Arg Asn Lys Lys Lys Glu Lys Thr Glu 
            100                 105                 110         


Cys Leu Gln Lys Glu Ser Glu Lys Leu Glu Ser Val Asn Ala Glu Leu 
        115                 120                 125             


Lys Ala Gln Ile Glu Glu Leu Lys Asn Glu Lys Gln His Leu Ile Tyr 
    130                 135                 140                 


Met Leu Asn Leu His Arg Pro Thr Cys Ile Val Arg Ala Gln Asn Gly 
145                 150                 155                 160 


Arg Thr Pro Glu Asp Glu Arg Asn Leu Phe Ile Gln Gln Ile Lys Glu 
                165                 170                 175     


Gly Thr Leu Gln Ser 
            180     


<210>  3881
<211>  781
<212>  PRT
<213>  homo sapiens

<400>  3881

Met Ala Thr Gln Ala Asp Leu Met Glu Leu Asp Met Ala Met Glu Pro 
1               5                   10                  15      


Asp Arg Lys Ala Ala Val Ser His Trp Gln Gln Gln Ser Tyr Leu Asp 
            20                  25                  30          


Ser Gly Ile His Ser Gly Ala Thr Thr Thr Ala Pro Ser Leu Ser Gly 
        35                  40                  45              


Lys Gly Asn Pro Glu Glu Glu Asp Val Asp Thr Ser Gln Val Leu Tyr 
    50                  55                  60                  


Glu Trp Glu Gln Gly Phe Ser Gln Ser Phe Thr Gln Glu Gln Val Ala 
65                  70                  75                  80  


Asp Ile Asp Gly Gln Tyr Ala Met Thr Arg Ala Gln Arg Val Arg Ala 
                85                  90                  95      


Ala Met Phe Pro Glu Thr Leu Asp Glu Gly Met Gln Ile Pro Ser Thr 
            100                 105                 110         


Gln Phe Asp Ala Ala His Pro Thr Asn Val Gln Arg Leu Ala Glu Pro 
        115                 120                 125             


Ser Gln Met Leu Lys His Ala Val Val Asn Leu Ile Asn Tyr Gln Asp 
    130                 135                 140                 


Asp Ala Glu Leu Ala Thr Arg Ala Ile Pro Glu Leu Thr Lys Leu Leu 
145                 150                 155                 160 


Asn Asp Glu Asp Gln Val Val Val Asn Lys Ala Ala Val Met Val His 
                165                 170                 175     


Gln Leu Ser Lys Lys Glu Ala Ser Arg His Ala Ile Met Arg Ser Pro 
            180                 185                 190         


Gln Met Val Ser Ala Ile Val Arg Thr Met Gln Asn Thr Asn Asp Val 
        195                 200                 205             


Glu Thr Ala Arg Cys Thr Ala Gly Thr Leu His Asn Leu Ser His His 
    210                 215                 220                 


Arg Glu Gly Leu Leu Ala Ile Phe Lys Ser Gly Gly Ile Pro Ala Leu 
225                 230                 235                 240 


Val Lys Met Leu Gly Ser Pro Val Asp Ser Val Leu Phe Tyr Ala Ile 
                245                 250                 255     


Thr Thr Leu His Asn Leu Leu Leu His Gln Glu Gly Ala Lys Met Ala 
            260                 265                 270         


Val Arg Leu Ala Gly Gly Leu Gln Lys Met Val Ala Leu Leu Asn Lys 
        275                 280                 285             


Thr Asn Val Lys Phe Leu Ala Ile Thr Thr Asp Cys Leu Gln Ile Leu 
    290                 295                 300                 


Ala Tyr Gly Asn Gln Glu Ser Lys Leu Ile Ile Leu Ala Ser Gly Gly 
305                 310                 315                 320 


Pro Gln Ala Leu Val Asn Ile Met Arg Thr Tyr Thr Tyr Glu Lys Leu 
                325                 330                 335     


Leu Trp Thr Thr Ser Arg Val Leu Lys Val Leu Ser Val Cys Ser Ser 
            340                 345                 350         


Asn Lys Pro Ala Ile Val Glu Ala Gly Gly Met Gln Ala Leu Gly Leu 
        355                 360                 365             


His Leu Thr Asp Pro Ser Gln Arg Leu Val Gln Asn Cys Leu Trp Thr 
    370                 375                 380                 


Leu Arg Asn Leu Ser Asp Ala Ala Thr Lys Gln Glu Gly Met Glu Gly 
385                 390                 395                 400 


Leu Leu Gly Thr Leu Val Gln Leu Leu Gly Ser Asp Asp Ile Asn Val 
                405                 410                 415     


Val Thr Cys Ala Ala Gly Ile Leu Ser Asn Leu Thr Cys Asn Asn Tyr 
            420                 425                 430         


Lys Asn Lys Met Met Val Cys Gln Val Gly Gly Ile Glu Ala Leu Val 
        435                 440                 445             


Arg Thr Val Leu Arg Ala Gly Asp Arg Glu Asp Ile Thr Glu Pro Ala 
    450                 455                 460                 


Ile Cys Ala Leu Arg His Leu Thr Ser Arg His Gln Glu Ala Glu Met 
465                 470                 475                 480 


Ala Gln Asn Ala Val Arg Leu His Tyr Gly Leu Pro Val Val Val Lys 
                485                 490                 495     


Leu Leu His Pro Pro Ser His Trp Pro Leu Ile Lys Ala Thr Val Gly 
            500                 505                 510         


Leu Ile Arg Asn Leu Ala Leu Cys Pro Ala Asn His Ala Pro Leu Arg 
        515                 520                 525             


Glu Gln Gly Ala Ile Pro Arg Leu Val Gln Leu Leu Val Arg Ala His 
    530                 535                 540                 


Gln Asp Thr Gln Arg Arg Thr Ser Met Gly Gly Thr Gln Gln Gln Phe 
545                 550                 555                 560 


Val Glu Gly Val Arg Met Glu Glu Ile Val Glu Gly Cys Thr Gly Ala 
                565                 570                 575     


Leu His Ile Leu Ala Arg Asp Val His Asn Arg Ile Val Ile Arg Gly 
            580                 585                 590         


Leu Asn Thr Ile Pro Leu Phe Val Gln Leu Leu Tyr Ser Pro Ile Glu 
        595                 600                 605             


Asn Ile Gln Arg Val Ala Ala Gly Val Leu Cys Glu Leu Ala Gln Asp 
    610                 615                 620                 


Lys Glu Ala Ala Glu Ala Ile Glu Ala Glu Gly Ala Thr Ala Pro Leu 
625                 630                 635                 640 


Thr Glu Leu Leu His Ser Arg Asn Glu Gly Val Ala Thr Tyr Ala Ala 
                645                 650                 655     


Ala Val Leu Phe Arg Met Ser Glu Asp Lys Pro Gln Asp Tyr Lys Lys 
            660                 665                 670         


Arg Leu Ser Val Glu Leu Thr Ser Ser Leu Phe Arg Thr Glu Pro Met 
        675                 680                 685             


Ala Trp Asn Glu Thr Ala Asp Leu Gly Leu Asp Ile Gly Ala Gln Gly 
    690                 695                 700                 


Glu Pro Leu Gly Tyr Arg Gln Asp Asp Pro Ser Tyr Arg Ser Phe His 
705                 710                 715                 720 


Ser Gly Gly Tyr Gly Gln Asp Ala Leu Gly Met Asp Pro Met Met Glu 
                725                 730                 735     


His Glu Met Gly Gly His His Pro Gly Ala Asp Tyr Pro Val Asp Gly 
            740                 745                 750         


Leu Pro Asp Leu Gly His Ala Gln Asp Leu Met Asp Gly Leu Pro Pro 
        755                 760                 765             


Gly Asp Ser Asn Gln Leu Ala Trp Phe Asp Thr Asp Leu 
    770                 775                 780     


<210>  3882
<211>  1212
<212>  PRT
<213>  homo sapiens

<400>  3882

Met Ala Asn Asp Ser Pro Ala Lys Ser Leu Val Asp Ile Asp Leu Ser 
1               5                   10                  15      


Ser Leu Arg Asp Pro Ala Gly Ile Phe Glu Leu Val Glu Val Val Gly 
            20                  25                  30          


Asn Gly Thr Tyr Gly Gln Val Tyr Lys Gly Arg His Val Lys Thr Gly 
        35                  40                  45              


Gln Leu Ala Ala Ile Lys Val Met Asp Val Thr Glu Asp Glu Glu Glu 
    50                  55                  60                  


Glu Ile Lys Leu Glu Ile Asn Met Leu Lys Lys Tyr Ser His His Arg 
65                  70                  75                  80  


Asn Ile Ala Thr Tyr Tyr Gly Ala Phe Ile Lys Lys Ser Pro Pro Gly 
                85                  90                  95      


His Asp Asp Gln Leu Trp Leu Val Met Glu Phe Cys Gly Ala Gly Ser 
            100                 105                 110         


Ile Thr Asp Leu Val Lys Asn Thr Lys Gly Asn Thr Leu Lys Glu Asp 
        115                 120                 125             


Trp Ile Ala Tyr Ile Ser Arg Glu Ile Leu Arg Gly Leu Ala His Leu 
    130                 135                 140                 


His Ile His His Val Ile His Arg Asp Ile Lys Gly Gln Asn Val Leu 
145                 150                 155                 160 


Leu Thr Glu Asn Ala Glu Val Lys Leu Val Asp Phe Gly Val Ser Ala 
                165                 170                 175     


Gln Leu Asp Arg Thr Val Gly Arg Arg Asn Thr Phe Ile Gly Thr Pro 
            180                 185                 190         


Tyr Trp Met Ala Pro Glu Val Ile Ala Cys Asp Glu Asn Pro Asp Ala 
        195                 200                 205             


Thr Tyr Asp Tyr Arg Ser Asp Leu Trp Ser Cys Gly Ile Thr Ala Ile 
    210                 215                 220                 


Glu Met Ala Glu Gly Ala Pro Pro Leu Cys Asp Met His Pro Met Arg 
225                 230                 235                 240 


Ala Leu Phe Leu Ile Pro Arg Asn Pro Pro Pro Arg Leu Lys Ser Lys 
                245                 250                 255     


Lys Trp Ser Lys Lys Phe Phe Ser Phe Ile Glu Gly Cys Leu Val Lys 
            260                 265                 270         


Asn Tyr Met Gln Arg Pro Ser Thr Glu Gln Leu Leu Lys His Pro Phe 
        275                 280                 285             


Ile Arg Asp Gln Pro Asn Glu Arg Gln Val Arg Ile Gln Leu Lys Asp 
    290                 295                 300                 


His Ile Asp Arg Thr Arg Lys Lys Arg Gly Glu Lys Asp Glu Thr Glu 
305                 310                 315                 320 


Tyr Glu Tyr Ser Gly Ser Glu Glu Glu Glu Glu Glu Val Pro Glu Gln 
                325                 330                 335     


Glu Gly Glu Pro Ser Ser Ile Val Asn Val Pro Gly Glu Ser Thr Leu 
            340                 345                 350         


Arg Arg Asp Phe Leu Arg Leu Gln Gln Glu Asn Lys Glu Arg Ser Glu 
        355                 360                 365             


Ala Leu Arg Arg Gln Gln Leu Leu Gln Glu Gln Gln Leu Arg Glu Gln 
    370                 375                 380                 


Glu Glu Tyr Lys Arg Gln Leu Leu Ala Glu Arg Gln Lys Arg Ile Glu 
385                 390                 395                 400 


Gln Gln Lys Glu Gln Arg Arg Arg Leu Glu Glu Gln Gln Arg Arg Glu 
                405                 410                 415     


Arg Glu Ala Arg Arg Gln Gln Glu Arg Glu Gln Arg Arg Arg Glu Gln 
            420                 425                 430         


Glu Glu Lys Arg Arg Leu Glu Glu Leu Glu Arg Arg Arg Lys Glu Glu 
        435                 440                 445             


Glu Glu Arg Arg Arg Ala Glu Glu Glu Lys Arg Arg Val Glu Arg Glu 
    450                 455                 460                 


Gln Glu Tyr Ile Arg Arg Gln Leu Glu Glu Glu Gln Arg His Leu Glu 
465                 470                 475                 480 


Val Leu Gln Gln Gln Leu Leu Gln Glu Gln Ala Met Leu Leu His Asp 
                485                 490                 495     


His Arg Arg Pro His Pro Gln His Ser Gln Gln Pro Pro Pro Pro Gln 
            500                 505                 510         


Gln Glu Arg Ser Lys Pro Ser Phe His Ala Pro Glu Pro Lys Ala His 
        515                 520                 525             


Tyr Glu Pro Ala Asp Arg Ala Arg Glu Val Glu Asp Arg Phe Arg Lys 
    530                 535                 540                 


Thr Asn His Ser Ser Pro Glu Ala Gln Ser Lys Gln Thr Gly Arg Val 
545                 550                 555                 560 


Leu Glu Pro Pro Val Pro Ser Arg Ser Glu Ser Phe Ser Asn Gly Asn 
                565                 570                 575     


Ser Glu Ser Val His Pro Ala Leu Gln Arg Pro Ala Glu Pro Gln Val 
            580                 585                 590         


Pro Val Arg Thr Thr Ser Arg Ser Pro Val Leu Ser Arg Arg Asp Ser 
        595                 600                 605             


Pro Leu Gln Gly Ser Gly Gln Gln Asn Ser Gln Ala Gly Gln Arg Asn 
    610                 615                 620                 


Ser Thr Ser Ser Ile Glu Pro Arg Leu Leu Trp Glu Arg Val Glu Lys 
625                 630                 635                 640 


Leu Val Pro Arg Pro Gly Ser Gly Ser Ser Ser Gly Ser Ser Asn Ser 
                645                 650                 655     


Gly Ser Gln Pro Gly Ser His Pro Gly Ser Gln Ser Gly Ser Gly Glu 
            660                 665                 670         


Arg Phe Arg Val Arg Ser Ser Ser Lys Ser Glu Gly Ser Pro Ser Gln 
        675                 680                 685             


Arg Leu Glu Asn Ala Val Lys Lys Pro Glu Asp Lys Lys Glu Val Phe 
    690                 695                 700                 


Arg Pro Leu Lys Pro Ala Gly Glu Val Asp Leu Thr Ala Leu Ala Lys 
705                 710                 715                 720 


Glu Leu Arg Ala Val Glu Asp Val Arg Pro Pro His Lys Val Thr Asp 
                725                 730                 735     


Tyr Ser Ser Ser Ser Glu Glu Ser Gly Thr Thr Asp Glu Glu Asp Asp 
            740                 745                 750         


Asp Val Glu Gln Glu Gly Ala Asp Glu Ser Thr Ser Gly Pro Glu Asp 
        755                 760                 765             


Thr Arg Ala Ala Ser Ser Leu Asn Leu Ser Asn Gly Glu Thr Glu Ser 
    770                 775                 780                 


Val Lys Thr Met Ile Val His Asp Asp Val Glu Ser Glu Pro Ala Met 
785                 790                 795                 800 


Thr Pro Ser Lys Glu Gly Thr Leu Ile Val Arg Gln Thr Gln Ser Ala 
                805                 810                 815     


Ser Ser Thr Leu Gln Lys His Lys Ser Ser Ser Ser Phe Thr Pro Phe 
            820                 825                 830         


Ile Asp Pro Arg Leu Leu Gln Ile Ser Pro Ser Ser Gly Thr Thr Val 
        835                 840                 845             


Thr Ser Val Val Gly Phe Ser Cys Asp Gly Met Arg Pro Glu Ala Ile 
    850                 855                 860                 


Arg Gln Asp Pro Thr Arg Lys Gly Ser Val Val Asn Val Asn Pro Thr 
865                 870                 875                 880 


Asn Thr Arg Pro Gln Ser Asp Thr Pro Glu Ile Arg Lys Tyr Lys Lys 
                885                 890                 895     


Arg Phe Asn Ser Glu Ile Leu Cys Ala Ala Leu Trp Gly Val Asn Leu 
            900                 905                 910         


Leu Val Gly Thr Glu Ser Gly Leu Met Leu Leu Asp Arg Ser Gly Gln 
        915                 920                 925             


Gly Lys Val Tyr Pro Leu Ile Asn Arg Arg Arg Phe Gln Gln Met Asp 
    930                 935                 940                 


Val Leu Glu Gly Leu Asn Val Leu Val Thr Ile Ser Gly Lys Lys Asp 
945                 950                 955                 960 


Lys Leu Arg Val Tyr Tyr Leu Ser Trp Leu Arg Asn Lys Ile Leu His 
                965                 970                 975     


Asn Asp Pro Glu Val Glu Lys Lys Gln Gly Trp Thr Thr Val Gly Asp 
            980                 985                 990         


Leu Glu Gly Cys Val His Tyr Lys  Val Val Lys Tyr Glu  Arg Ile Lys 
        995                 1000                 1005             


Phe Leu  Val Ile Ala Leu Lys  Ser Ser Val Glu Val  Tyr Ala Trp 
    1010                 1015                 1020             


Ala Pro  Lys Pro Tyr His Lys  Phe Met Ala Phe Lys  Ser Phe Gly 
    1025                 1030                 1035             


Glu Leu  Val His Lys Pro Leu  Leu Val Asp Leu Thr  Val Glu Glu 
    1040                 1045                 1050             


Gly Gln  Arg Leu Lys Val Ile  Tyr Gly Ser Cys Ala  Gly Phe His 
    1055                 1060                 1065             


Ala Val  Asp Val Asp Ser Gly  Ser Val Tyr Asp Ile  Tyr Leu Pro 
    1070                 1075                 1080             


Thr His  Ile Gln Cys Ser Ile  Lys Pro His Ala Ile  Ile Ile Leu 
    1085                 1090                 1095             


Pro Asn  Thr Asp Gly Met Glu  Leu Leu Val Cys Tyr  Glu Asp Glu 
    1100                 1105                 1110             


Gly Val  Tyr Val Asn Thr Tyr  Gly Arg Ile Thr Lys  Asp Val Val 
    1115                 1120                 1125             


Leu Gln  Trp Gly Glu Met Pro  Thr Ser Val Ala Tyr  Ile Arg Ser 
    1130                 1135                 1140             


Asn Gln  Thr Met Gly Trp Gly  Glu Lys Ala Ile Glu  Ile Arg Ser 
    1145                 1150                 1155             


Val Glu  Thr Gly His Leu Asp  Gly Val Phe Met His  Lys Arg Ala 
    1160                 1165                 1170             


Gln Arg  Leu Lys Phe Leu Cys  Glu Arg Asn Asp Lys  Val Phe Phe 
    1175                 1180                 1185             


Ala Ser  Val Arg Ser Gly Gly  Ser Ser Gln Val Tyr  Phe Met Thr 
    1190                 1195                 1200             


Leu Gly  Arg Thr Ser Leu Leu  Ser Trp 
    1205                 1210         


<210>  3883
<211>  1165
<212>  PRT
<213>  homo sapiens

<400>  3883

Met Ala Asn Asp Ser Pro Ala Lys Ser Leu Val Asp Ile Asp Leu Ser 
1               5                   10                  15      


Ser Leu Arg Asp Pro Ala Gly Ile Phe Glu Leu Val Glu Val Val Gly 
            20                  25                  30          


Asn Gly Thr Tyr Gly Gln Val Tyr Lys Gly Arg His Val Lys Thr Gly 
        35                  40                  45              


Gln Leu Ala Ala Ile Lys Val Met Asp Val Thr Glu Asp Glu Glu Glu 
    50                  55                  60                  


Glu Ile Lys Leu Glu Ile Asn Met Leu Lys Lys Tyr Ser His His Arg 
65                  70                  75                  80  


Asn Ile Ala Thr Tyr Tyr Gly Ala Phe Ile Lys Lys Ser Pro Pro Gly 
                85                  90                  95      


His Asp Asp Gln Leu Trp Leu Val Met Glu Phe Cys Gly Ala Gly Ser 
            100                 105                 110         


Ile Thr Asp Leu Val Lys Asn Thr Lys Gly Asn Thr Leu Lys Glu Asp 
        115                 120                 125             


Trp Ile Ala Tyr Ile Ser Arg Glu Ile Leu Arg Gly Leu Ala His Leu 
    130                 135                 140                 


His Ile His His Val Ile His Arg Asp Ile Lys Gly Gln Asn Val Leu 
145                 150                 155                 160 


Leu Thr Glu Asn Ala Glu Val Lys Leu Val Asp Phe Gly Val Ser Ala 
                165                 170                 175     


Gln Leu Asp Arg Thr Val Gly Arg Arg Asn Thr Phe Ile Gly Thr Pro 
            180                 185                 190         


Tyr Trp Met Ala Pro Glu Val Ile Ala Cys Asp Glu Asn Pro Asp Ala 
        195                 200                 205             


Thr Tyr Asp Tyr Arg Ser Asp Leu Trp Ser Cys Gly Ile Thr Ala Ile 
    210                 215                 220                 


Glu Met Ala Glu Gly Ala Pro Pro Leu Cys Asp Met His Pro Met Arg 
225                 230                 235                 240 


Ala Leu Phe Leu Ile Pro Arg Asn Pro Pro Pro Arg Leu Lys Ser Lys 
                245                 250                 255     


Lys Trp Ser Lys Lys Phe Phe Ser Phe Ile Glu Gly Cys Leu Val Lys 
            260                 265                 270         


Asn Tyr Met Gln Arg Pro Ser Thr Glu Gln Leu Leu Lys His Pro Phe 
        275                 280                 285             


Ile Arg Asp Gln Pro Asn Glu Arg Gln Val Arg Ile Gln Leu Lys Asp 
    290                 295                 300                 


His Ile Asp Arg Thr Arg Lys Lys Arg Gly Glu Lys Asp Glu Thr Glu 
305                 310                 315                 320 


Tyr Glu Tyr Ser Gly Ser Glu Glu Glu Glu Glu Glu Val Pro Glu Gln 
                325                 330                 335     


Glu Gly Glu Pro Ser Ser Ile Val Asn Val Pro Gly Glu Ser Thr Leu 
            340                 345                 350         


Arg Arg Asp Phe Leu Arg Leu Gln Gln Glu Asn Lys Glu Arg Ser Glu 
        355                 360                 365             


Ala Leu Arg Arg Gln Gln Leu Leu Gln Glu Gln Gln Leu Arg Glu Gln 
    370                 375                 380                 


Glu Glu Tyr Lys Arg Gln Leu Leu Ala Glu Arg Gln Lys Arg Ile Glu 
385                 390                 395                 400 


Gln Gln Lys Glu Gln Arg Arg Arg Leu Glu Glu Gln Gln Arg Arg Glu 
                405                 410                 415     


Arg Glu Ala Arg Arg Gln Gln Glu Arg Glu Gln Arg Arg Arg Glu Gln 
            420                 425                 430         


Glu Glu Lys Arg Arg Leu Glu Glu Leu Glu Arg Arg Arg Lys Glu Glu 
        435                 440                 445             


Glu Glu Arg Arg Arg Ala Glu Glu Glu Lys Arg Arg Val Glu Arg Glu 
    450                 455                 460                 


Gln Glu Tyr Ile Arg Arg Gln Leu Glu Glu Glu Gln Arg His Leu Glu 
465                 470                 475                 480 


Val Leu Gln Gln Gln Leu Leu Gln Glu Gln Ala Met Leu Leu His Asp 
                485                 490                 495     


His Arg Arg Pro His Pro Gln His Ser Gln Gln Pro Pro Pro Pro Gln 
            500                 505                 510         


Gln Glu Arg Ser Lys Pro Ser Phe His Ala Pro Glu Pro Lys Ala His 
        515                 520                 525             


Tyr Glu Pro Ala Asp Arg Ala Arg Glu Val Pro Val Arg Thr Thr Ser 
    530                 535                 540                 


Arg Ser Pro Val Leu Ser Arg Arg Asp Ser Pro Leu Gln Gly Ser Gly 
545                 550                 555                 560 


Gln Gln Asn Ser Gln Ala Gly Gln Arg Asn Ser Thr Ser Ile Glu Pro 
                565                 570                 575     


Arg Leu Leu Trp Glu Arg Val Glu Lys Leu Val Pro Arg Pro Gly Ser 
            580                 585                 590         


Gly Ser Ser Ser Gly Ser Ser Asn Ser Gly Ser Gln Pro Gly Ser His 
        595                 600                 605             


Pro Gly Ser Gln Ser Gly Ser Gly Glu Arg Phe Arg Val Arg Ser Ser 
    610                 615                 620                 


Ser Lys Ser Glu Gly Ser Pro Ser Gln Arg Leu Glu Asn Ala Val Lys 
625                 630                 635                 640 


Lys Pro Glu Asp Lys Lys Glu Val Phe Arg Pro Leu Lys Pro Ala Gly 
                645                 650                 655     


Glu Val Asp Leu Thr Ala Leu Ala Lys Glu Leu Arg Ala Val Glu Asp 
            660                 665                 670         


Val Arg Pro Pro His Lys Val Thr Asp Tyr Ser Ser Ser Ser Glu Glu 
        675                 680                 685             


Ser Gly Thr Thr Asp Glu Glu Asp Asp Asp Val Glu Gln Glu Gly Ala 
    690                 695                 700                 


Asp Glu Ser Thr Ser Gly Pro Glu Asp Thr Arg Ala Ala Ser Ser Leu 
705                 710                 715                 720 


Asn Leu Ser Asn Gly Glu Thr Glu Ser Val Lys Thr Met Ile Val His 
                725                 730                 735     


Asp Asp Val Glu Ser Glu Pro Ala Met Thr Pro Ser Lys Glu Gly Thr 
            740                 745                 750         


Leu Ile Val Arg Gln Thr Gln Ser Ala Ser Ser Thr Leu Gln Lys His 
        755                 760                 765             


Lys Ser Ser Ser Ser Phe Thr Pro Phe Ile Asp Pro Arg Leu Leu Gln 
    770                 775                 780                 


Ile Ser Pro Ser Ser Gly Thr Thr Val Thr Ser Val Val Gly Phe Ser 
785                 790                 795                 800 


Cys Asp Gly Met Arg Pro Glu Ala Ile Arg Gln Asp Pro Thr Arg Lys 
                805                 810                 815     


Gly Ser Val Val Asn Val Asn Pro Thr Asn Thr Arg Pro Gln Ser Asp 
            820                 825                 830         


Thr Pro Glu Ile Arg Lys Tyr Lys Lys Arg Phe Asn Ser Glu Ile Leu 
        835                 840                 845             


Cys Ala Ala Leu Trp Gly Val Asn Leu Leu Val Gly Thr Glu Ser Gly 
    850                 855                 860                 


Leu Met Leu Leu Asp Arg Ser Gly Gln Gly Lys Val Tyr Pro Leu Ile 
865                 870                 875                 880 


Asn Arg Arg Arg Phe Gln Gln Met Asp Val Leu Glu Gly Leu Asn Val 
                885                 890                 895     


Leu Val Thr Ile Ser Gly Lys Lys Asp Lys Leu Arg Val Tyr Tyr Leu 
            900                 905                 910         


Ser Trp Leu Arg Asn Lys Ile Leu His Asn Asp Pro Glu Val Glu Lys 
        915                 920                 925             


Lys Gln Gly Trp Thr Thr Val Gly Asp Leu Glu Gly Cys Val His Tyr 
    930                 935                 940                 


Lys Val Val Lys Tyr Glu Arg Ile Lys Phe Leu Val Ile Ala Leu Lys 
945                 950                 955                 960 


Ser Ser Val Glu Val Tyr Ala Trp Ala Pro Lys Pro Tyr His Lys Phe 
                965                 970                 975     


Met Ala Phe Lys Ser Phe Gly Glu Leu Val His Lys Pro Leu Leu Val 
            980                 985                 990         


Asp Leu Thr Val Glu Glu Gly Gln  Arg Leu Lys Val Ile  Tyr Gly Ser 
        995                 1000                 1005             


Cys Ala  Gly Phe His Ala Val  Asp Val Asp Ser Gly  Ser Val Tyr 
    1010                 1015                 1020             


Asp Ile  Tyr Leu Pro Thr His  Val Arg Lys Asn Pro  His Ser Met 
    1025                 1030                 1035             


Ile Gln  Cys Ser Ile Lys Pro  His Ala Ile Ile Ile  Leu Pro Asn 
    1040                 1045                 1050             


Thr Asp  Gly Met Glu Leu Leu  Val Cys Tyr Glu Asp  Glu Gly Val 
    1055                 1060                 1065             


Tyr Val  Asn Thr Tyr Gly Arg  Ile Thr Lys Asp Val  Val Leu Gln 
    1070                 1075                 1080             


Trp Gly  Glu Met Pro Thr Ser  Val Ala Tyr Ile Arg  Ser Asn Gln 
    1085                 1090                 1095             


Thr Met  Gly Trp Gly Glu Lys  Ala Ile Glu Ile Arg  Ser Val Glu 
    1100                 1105                 1110             


Thr Gly  His Leu Asp Gly Val  Phe Met His Lys Arg  Ala Gln Arg 
    1115                 1120                 1125             


Leu Lys  Phe Leu Cys Glu Arg  Asn Asp Lys Val Phe  Phe Ala Ser 
    1130                 1135                 1140             


Val Arg  Ser Gly Gly Ser Ser  Gln Val Tyr Phe Met  Thr Leu Gly 
    1145                 1150                 1155             


Arg Thr  Ser Leu Leu Ser Trp  
    1160                 1165 


<210>  3884
<211>  1273
<212>  PRT
<213>  homo sapiens

<400>  3884

Met Ala Asn Asp Ser Pro Ala Lys Ser Leu Val Asp Ile Asp Leu Ser 
1               5                   10                  15      


Ser Leu Arg Asp Pro Ala Gly Ile Phe Glu Leu Val Glu Val Val Gly 
            20                  25                  30          


Asn Gly Thr Tyr Gly Gln Val Tyr Lys Gly Arg His Val Lys Thr Gly 
        35                  40                  45              


Gln Leu Ala Ala Ile Lys Val Met Asp Val Thr Glu Asp Glu Glu Glu 
    50                  55                  60                  


Glu Ile Lys Leu Glu Ile Asn Met Leu Lys Lys Tyr Ser His His Arg 
65                  70                  75                  80  


Asn Ile Ala Thr Tyr Tyr Gly Ala Phe Ile Lys Lys Ser Pro Pro Gly 
                85                  90                  95      


His Asp Asp Gln Leu Trp Leu Val Met Glu Phe Cys Gly Ala Gly Ser 
            100                 105                 110         


Ile Thr Asp Leu Val Lys Asn Thr Lys Gly Asn Thr Leu Lys Glu Asp 
        115                 120                 125             


Trp Ile Ala Tyr Ile Ser Arg Glu Ile Leu Arg Gly Leu Ala His Leu 
    130                 135                 140                 


His Ile His His Val Ile His Arg Asp Ile Lys Gly Gln Asn Val Leu 
145                 150                 155                 160 


Leu Thr Glu Asn Ala Glu Val Lys Leu Val Asp Phe Gly Val Ser Ala 
                165                 170                 175     


Gln Leu Asp Arg Thr Val Gly Arg Arg Asn Thr Phe Ile Gly Thr Pro 
            180                 185                 190         


Tyr Trp Met Ala Pro Glu Val Ile Ala Cys Asp Glu Asn Pro Asp Ala 
        195                 200                 205             


Thr Tyr Asp Tyr Arg Ser Asp Leu Trp Ser Cys Gly Ile Thr Ala Ile 
    210                 215                 220                 


Glu Met Ala Glu Gly Ala Pro Pro Leu Cys Asp Met His Pro Met Arg 
225                 230                 235                 240 


Ala Leu Phe Leu Ile Pro Arg Asn Pro Pro Pro Arg Leu Lys Ser Lys 
                245                 250                 255     


Lys Trp Ser Lys Lys Phe Phe Ser Phe Ile Glu Gly Cys Leu Val Lys 
            260                 265                 270         


Asn Tyr Met Gln Arg Pro Ser Thr Glu Gln Leu Leu Lys His Pro Phe 
        275                 280                 285             


Ile Arg Asp Gln Pro Asn Glu Arg Gln Val Arg Ile Gln Leu Lys Asp 
    290                 295                 300                 


His Ile Asp Arg Thr Arg Lys Lys Arg Gly Glu Lys Asp Glu Thr Glu 
305                 310                 315                 320 


Tyr Glu Tyr Ser Gly Ser Glu Glu Glu Glu Glu Glu Val Pro Glu Gln 
                325                 330                 335     


Glu Gly Glu Pro Ser Ser Ile Val Asn Val Pro Gly Glu Ser Thr Leu 
            340                 345                 350         


Arg Arg Asp Phe Leu Arg Leu Gln Gln Glu Asn Lys Glu Arg Ser Glu 
        355                 360                 365             


Ala Leu Arg Arg Gln Gln Leu Leu Gln Glu Gln Gln Leu Arg Glu Gln 
    370                 375                 380                 


Glu Glu Tyr Lys Arg Gln Leu Leu Ala Glu Arg Gln Lys Arg Ile Glu 
385                 390                 395                 400 


Gln Gln Lys Glu Gln Arg Arg Arg Leu Glu Glu Gln Gln Arg Arg Glu 
                405                 410                 415     


Arg Glu Ala Arg Arg Gln Gln Glu Arg Glu Gln Arg Arg Arg Glu Gln 
            420                 425                 430         


Glu Glu Lys Arg Arg Leu Glu Glu Leu Glu Arg Arg Arg Lys Glu Glu 
        435                 440                 445             


Glu Glu Arg Arg Arg Ala Glu Glu Glu Lys Arg Arg Val Glu Arg Glu 
    450                 455                 460                 


Gln Glu Tyr Ile Arg Arg Gln Leu Glu Glu Glu Gln Arg His Leu Glu 
465                 470                 475                 480 


Val Leu Gln Gln Gln Leu Leu Gln Glu Gln Ala Met Leu Leu His Asp 
                485                 490                 495     


His Arg Arg Pro His Pro Gln His Ser Gln Gln Pro Pro Pro Pro Gln 
            500                 505                 510         


Gln Glu Arg Ser Lys Pro Ser Phe His Ala Pro Glu Pro Lys Ala His 
        515                 520                 525             


Tyr Glu Pro Ala Asp Arg Ala Arg Glu Val Glu Asp Arg Phe Arg Lys 
    530                 535                 540                 


Thr Asn His Ser Ser Pro Glu Ala Gln Ser Lys Gln Thr Gly Arg Val 
545                 550                 555                 560 


Leu Glu Pro Pro Val Pro Ser Arg Ser Glu Ser Phe Ser Asn Gly Asn 
                565                 570                 575     


Ser Glu Ser Val His Pro Ala Leu Gln Arg Pro Ala Glu Pro Gln Val 
            580                 585                 590         


Pro Val Arg Thr Thr Ser Arg Ser Pro Val Leu Ser Arg Arg Asp Ser 
        595                 600                 605             


Pro Leu Gln Gly Ser Gly Gln Gln Asn Ser Gln Ala Gly Gln Arg Asn 
    610                 615                 620                 


Ser Thr Ser Ser Ile Glu Pro Arg Leu Leu Trp Glu Arg Val Glu Lys 
625                 630                 635                 640 


Leu Val Pro Arg Pro Gly Ser Gly Ser Ser Ser Gly Ser Ser Asn Ser 
                645                 650                 655     


Gly Ser Gln Pro Gly Ser His Pro Gly Ser Gln Ser Gly Ser Gly Glu 
            660                 665                 670         


Arg Phe Arg Val Arg Ser Ser Ser Lys Ser Glu Gly Ser Pro Ser Gln 
        675                 680                 685             


Arg Leu Glu Asn Ala Val Lys Lys Pro Glu Asp Lys Lys Glu Val Phe 
    690                 695                 700                 


Arg Pro Leu Lys Pro Ala Asp Leu Thr Ala Leu Ala Lys Glu Leu Arg 
705                 710                 715                 720 


Ala Val Glu Asp Val Arg Pro Pro His Lys Val Thr Asp Tyr Ser Ser 
                725                 730                 735     


Ser Ser Glu Glu Ser Gly Thr Thr Asp Glu Glu Asp Asp Asp Val Glu 
            740                 745                 750         


Gln Glu Gly Ala Asp Glu Ser Thr Ser Gly Pro Glu Asp Thr Arg Ala 
        755                 760                 765             


Ala Ser Ser Leu Asn Leu Ser Asn Gly Glu Thr Glu Ser Val Lys Thr 
    770                 775                 780                 


Met Ile Val His Asp Asp Val Glu Ser Glu Pro Ala Met Thr Pro Ser 
785                 790                 795                 800 


Lys Glu Gly Thr Leu Ile Val Arg Gln Ser Thr Val Asp Gln Lys Arg 
                805                 810                 815     


Ala Ser His His Glu Ser Asn Gly Phe Ala Gly Arg Ile His Leu Leu 
            820                 825                 830         


Pro Asp Leu Leu Gln Gln Ser His Ser Ser Ser Thr Ser Ser Thr Ser 
        835                 840                 845             


Ser Ser Pro Ser Ser Ser Gln Pro Thr Pro Thr Met Ser Pro Gln Thr 
    850                 855                 860                 


Pro Gln Asp Lys Leu Thr Ala Asn Glu Thr Gln Ser Ala Ser Ser Thr 
865                 870                 875                 880 


Leu Gln Lys His Lys Ser Ser Ser Ser Phe Thr Pro Phe Ile Asp Pro 
                885                 890                 895     


Arg Leu Leu Gln Ile Ser Pro Ser Ser Gly Thr Thr Val Thr Ser Val 
            900                 905                 910         


Val Gly Phe Ser Cys Asp Gly Met Arg Pro Glu Ala Ile Arg Gln Asp 
        915                 920                 925             


Pro Thr Arg Lys Gly Ser Val Val Asn Val Asn Pro Thr Asn Thr Arg 
    930                 935                 940                 


Pro Gln Ser Asp Thr Pro Glu Ile Arg Lys Tyr Lys Lys Arg Phe Asn 
945                 950                 955                 960 


Ser Glu Ile Leu Cys Ala Ala Leu Trp Gly Val Asn Leu Leu Val Gly 
                965                 970                 975     


Thr Glu Ser Gly Leu Met Leu Leu Asp Arg Ser Gly Gln Gly Lys Val 
            980                 985                 990         


Tyr Pro Leu Ile Asn Arg Arg Arg  Phe Gln Gln Met Asp  Val Leu Glu 
        995                 1000                 1005             


Gly Leu  Asn Val Leu Val Thr  Ile Ser Gly Lys Lys  Asp Lys Leu 
    1010                 1015                 1020             


Arg Val  Tyr Tyr Leu Ser Trp  Leu Arg Asn Lys Ile  Leu His Asn 
    1025                 1030                 1035             


Asp Pro  Glu Val Glu Lys Lys  Gln Gly Trp Thr Thr  Val Gly Asp 
    1040                 1045                 1050             


Leu Glu  Gly Cys Val His Tyr  Lys Val Val Lys Tyr  Glu Arg Ile 
    1055                 1060                 1065             


Lys Phe  Leu Val Ile Ala Leu  Lys Ser Ser Val Glu  Val Tyr Ala 
    1070                 1075                 1080             


Trp Ala  Pro Lys Pro Tyr His  Lys Phe Met Ala Phe  Lys Ser Phe 
    1085                 1090                 1095             


Gly Glu  Leu Val His Lys Pro  Leu Leu Val Asp Leu  Thr Val Glu 
    1100                 1105                 1110             


Glu Gly  Gln Arg Leu Lys Val  Ile Tyr Gly Ser Cys  Ala Gly Phe 
    1115                 1120                 1125             


His Ala  Val Asp Val Asp Ser  Gly Ser Val Tyr Asp  Ile Tyr Leu 
    1130                 1135                 1140             


Pro Thr  His Ile Gln Cys Ser  Ile Lys Pro His Ala  Ile Ile Ile 
    1145                 1150                 1155             


Leu Pro  Asn Thr Asp Gly Met  Glu Leu Leu Val Cys  Tyr Glu Asp 
    1160                 1165                 1170             


Glu Gly  Val Tyr Val Asn Thr  Tyr Gly Arg Ile Thr  Lys Asp Val 
    1175                 1180                 1185             


Val Leu  Gln Trp Gly Glu Met  Pro Thr Ser Val Ala  Tyr Ile Arg 
    1190                 1195                 1200             


Ser Asn  Gln Thr Met Gly Trp  Gly Glu Lys Ala Ile  Glu Ile Arg 
    1205                 1210                 1215             


Ser Val  Glu Thr Gly His Leu  Asp Gly Val Phe Met  His Lys Arg 
    1220                 1225                 1230             


Ala Gln  Arg Leu Lys Phe Leu  Cys Glu Arg Asn Asp  Lys Val Phe 
    1235                 1240                 1245             


Phe Ala  Ser Val Arg Ser Gly  Gly Ser Ser Gln Val  Tyr Phe Met 
    1250                 1255                 1260             


Thr Leu  Gly Arg Thr Ser Leu  Leu Ser Trp 
    1265                 1270             


<210>  3885
<211>  846
<212>  PRT
<213>  homo sapiens

<400>  3885

Met Glu Ala Pro Leu Arg Pro Ala Ala Asp Ile Leu Arg Arg Asn Pro 
1               5                   10                  15      


Gln Gln Asp Tyr Glu Leu Val Gln Arg Val Gly Ser Gly Thr Tyr Gly 
            20                  25                  30          


Asp Val Tyr Lys Ala Arg Asn Val His Thr Gly Glu Leu Ala Ala Val 
        35                  40                  45              


Lys Ile Ile Lys Leu Glu Pro Gly Asp Asp Phe Ser Leu Ile Gln Gln 
    50                  55                  60                  


Glu Ile Phe Met Val Lys Glu Cys Lys His Cys Asn Ile Val Ala Tyr 
65                  70                  75                  80  


Phe Gly Ser Tyr Leu Ser Arg Glu Lys Leu Trp Ile Cys Met Glu Tyr 
                85                  90                  95      


Cys Gly Gly Gly Ser Leu Gln Asp Ile Tyr His Val Thr Gly Pro Leu 
            100                 105                 110         


Ser Glu Leu Gln Ile Ala Tyr Val Cys Arg Glu Thr Leu Gln Gly Leu 
        115                 120                 125             


Ala Tyr Leu His Thr Lys Gly Lys Met His Arg Asp Ile Lys Gly Ala 
    130                 135                 140                 


Asn Ile Leu Leu Thr Asp His Gly Asp Val Lys Leu Ala Asp Phe Gly 
145                 150                 155                 160 


Val Ala Ala Lys Ile Thr Ala Thr Ile Ala Lys Arg Lys Ser Phe Ile 
                165                 170                 175     


Gly Thr Pro Tyr Trp Met Ala Pro Glu Val Ala Ala Val Glu Lys Asn 
            180                 185                 190         


Gly Gly Tyr Asn Gln Leu Cys Asp Ile Trp Ala Val Gly Ile Thr Ala 
        195                 200                 205             


Ile Glu Leu Gly Glu Leu Gln Pro Pro Met Phe Asp Leu His Pro Met 
    210                 215                 220                 


Arg Ala Leu Phe Leu Met Ser Lys Ser Asn Phe Gln Pro Pro Lys Leu 
225                 230                 235                 240 


Lys Asp Lys Thr Lys Trp Ser Ser Thr Phe His Asn Phe Val Lys Ile 
                245                 250                 255     


Ala Leu Thr Lys Asn Pro Lys Lys Arg Pro Thr Ala Glu Arg Leu Leu 
            260                 265                 270         


Thr His Thr Phe Val Ala Gln Pro Gly Leu Ser Arg Ala Leu Ala Val 
        275                 280                 285             


Glu Leu Leu Asp Lys Val Asn Asn Pro Asp Asn His Ala His Tyr Thr 
    290                 295                 300                 


Glu Ala Asp Asp Asp Asp Phe Glu Pro His Ala Ile Ile Arg His Thr 
305                 310                 315                 320 


Ile Arg Ser Thr Asn Arg Asn Ala Arg Ala Glu Arg Thr Ala Ser Glu 
                325                 330                 335     


Ile Asn Phe Asp Lys Leu Gln Phe Glu Pro Pro Leu Arg Lys Glu Thr 
            340                 345                 350         


Glu Ala Arg Asp Glu Met Gly Leu Ser Ser Asp Pro Asn Phe Met Leu 
        355                 360                 365             


Gln Trp Asn Pro Phe Val Asp Gly Ala Asn Thr Gly Lys Ser Thr Ser 
    370                 375                 380                 


Lys Arg Ala Ile Pro Pro Pro Leu Pro Pro Lys Pro Arg Ile Ser Ser 
385                 390                 395                 400 


Tyr Pro Glu Asp Asn Phe Pro Asp Glu Glu Lys Ala Ser Thr Ile Lys 
                405                 410                 415     


His Cys Pro Asp Ser Glu Ser Arg Ala Pro Gln Ile Leu Arg Arg Gln 
            420                 425                 430         


Ser Ser Pro Ser Cys Gly Pro Val Ala Glu Thr Ser Ser Ile Gly Asn 
        435                 440                 445             


Gly Asp Gly Ile Ser Lys Leu Met Ser Glu Asn Thr Glu Gly Ser Ala 
    450                 455                 460                 


Gln Ala Pro Gln Leu Pro Arg Lys Lys Asp Lys Arg Asp Phe Pro Lys 
465                 470                 475                 480 


Pro Ala Ile Asn Gly Leu Pro Pro Thr Pro Lys Val Leu Met Gly Ala 
                485                 490                 495     


Cys Phe Ser Lys Val Phe Asp Gly Cys Pro Leu Lys Ile Asn Cys Ala 
            500                 505                 510         


Thr Ser Trp Ile His Pro Asp Thr Lys Asp Gln Tyr Ile Ile Phe Gly 
        515                 520                 525             


Thr Glu Asp Gly Ile Tyr Thr Leu Asn Leu Asn Glu Leu His Glu Ala 
    530                 535                 540                 


Thr Met Glu Gln Leu Phe Pro Arg Lys Cys Thr Trp Leu Tyr Val Ile 
545                 550                 555                 560 


Asn Asn Thr Leu Met Ser Leu Ser Glu Gly Lys Thr Phe Gln Leu Tyr 
                565                 570                 575     


Ser His Asn Leu Ile Ala Leu Phe Glu His Ala Lys Lys Pro Gly Leu 
            580                 585                 590         


Ala Ala His Ile Gln Thr His Arg Phe Pro Asp Arg Ile Leu Pro Arg 
        595                 600                 605             


Lys Phe Ala Leu Thr Thr Lys Ile Pro Asp Thr Lys Gly Cys His Lys 
    610                 615                 620                 


Cys Cys Ile Val Arg Asn Pro Tyr Thr Gly His Lys Tyr Leu Cys Gly 
625                 630                 635                 640 


Ala Leu Gln Ser Gly Ile Val Leu Leu Gln Trp Tyr Glu Pro Met Gln 
                645                 650                 655     


Lys Phe Met Leu Ile Lys His Phe Asp Phe Pro Leu Pro Ser Pro Leu 
            660                 665                 670         


Asn Val Phe Glu Met Leu Val Ile Pro Glu Gln Glu Tyr Pro Met Val 
        675                 680                 685             


Cys Val Ala Ile Ser Lys Gly Thr Glu Ser Asn Gln Val Val Gln Phe 
    690                 695                 700                 


Glu Thr Ile Asn Leu Asn Ser Ala Ser Ser Trp Phe Thr Glu Ile Gly 
705                 710                 715                 720 


Ala Gly Ser Gln Gln Leu Asp Ser Ile His Val Thr Gln Leu Glu Arg 
                725                 730                 735     


Asp Thr Val Leu Val Cys Leu Asp Lys Phe Val Lys Ile Val Asn Leu 
            740                 745                 750         


Gln Gly Lys Leu Lys Ser Ser Lys Lys Leu Ala Ser Glu Leu Ser Phe 
        755                 760                 765             


Asp Phe Arg Ile Glu Ser Val Val Cys Leu Gln Asp Ser Val Leu Ala 
    770                 775                 780                 


Phe Trp Lys His Gly Met Gln Gly Lys Ser Phe Lys Ser Asp Glu Val 
785                 790                 795                 800 


Thr Gln Glu Ile Ser Asp Glu Thr Arg Val Phe Arg Leu Leu Gly Ser 
                805                 810                 815     


Asp Arg Val Val Val Leu Glu Ser Arg Pro Thr Glu Asn Pro Thr Ala 
            820                 825                 830         


His Ser Asn Leu Tyr Ile Leu Ala Gly His Glu Asn Ser Tyr 
        835                 840                 845     


<210>  3886
<211>  960
<212>  PRT
<213>  homo sapiens

<400>  3886

Met Lys Ser Ala Arg Ala Lys Thr Pro Arg Lys Pro Thr Val Lys Lys 
1               5                   10                  15      


Gly Ser Gln Thr Asn Leu Lys Asp Pro Val Gly Val Tyr Cys Arg Val 
            20                  25                  30          


Arg Pro Leu Gly Phe Pro Asp Gln Glu Cys Cys Ile Glu Val Ile Asn 
        35                  40                  45              


Asn Thr Thr Val Gln Leu His Thr Pro Glu Gly Tyr Arg Leu Asn Arg 
    50                  55                  60                  


Asn Gly Asp Tyr Lys Glu Thr Gln Tyr Ser Phe Lys Gln Val Phe Gly 
65                  70                  75                  80  


Thr His Thr Thr Gln Lys Glu Leu Phe Asp Val Val Ala Asn Pro Leu 
                85                  90                  95      


Val Asn Asp Leu Ile His Gly Lys Asn Gly Leu Leu Phe Thr Tyr Gly 
            100                 105                 110         


Val Thr Gly Ser Gly Lys Thr His Thr Met Thr Gly Ser Pro Gly Glu 
        115                 120                 125             


Gly Gly Leu Leu Pro Arg Cys Leu Asp Met Ile Phe Asn Ser Ile Gly 
    130                 135                 140                 


Ser Phe Gln Ala Lys Arg Tyr Val Phe Lys Ser Asn Asp Arg Asn Ser 
145                 150                 155                 160 


Met Asp Ile Gln Cys Glu Val Asp Ala Leu Leu Glu Arg Gln Lys Arg 
                165                 170                 175     


Glu Ala Met Pro Asn Pro Lys Thr Ser Ser Ser Lys Arg Gln Val Asp 
            180                 185                 190         


Pro Glu Phe Ala Asp Met Ile Thr Val Gln Glu Phe Cys Lys Ala Glu 
        195                 200                 205             


Glu Val Asp Glu Asp Ser Val Tyr Gly Val Phe Val Ser Tyr Ile Glu 
    210                 215                 220                 


Ile Tyr Asn Asn Tyr Ile Tyr Asp Leu Leu Glu Glu Val Pro Phe Asp 
225                 230                 235                 240 


Pro Ile Lys Pro Lys Pro Pro Gln Ser Lys Leu Leu Arg Glu Asp Lys 
                245                 250                 255     


Asn His Asn Met Tyr Val Ala Gly Cys Thr Glu Val Glu Val Lys Ser 
            260                 265                 270         


Thr Glu Glu Ala Phe Glu Val Phe Trp Arg Gly Gln Lys Lys Arg Arg 
        275                 280                 285             


Ile Ala Asn Thr His Leu Asn Arg Glu Ser Ser Arg Ser His Ser Val 
    290                 295                 300                 


Phe Asn Ile Lys Leu Val Gln Ala Pro Leu Asp Ala Asp Gly Asp Asn 
305                 310                 315                 320 


Val Leu Gln Glu Lys Glu Gln Ile Thr Ile Ser Gln Leu Ser Leu Val 
                325                 330                 335     


Asp Leu Ala Gly Ser Glu Arg Thr Asn Arg Thr Arg Ala Glu Gly Asn 
            340                 345                 350         


Arg Leu Arg Glu Ala Gly Asn Ile Asn Gln Ser Leu Met Thr Leu Arg 
        355                 360                 365             


Thr Cys Met Asp Val Leu Arg Glu Asn Gln Met Tyr Gly Thr Asn Lys 
    370                 375                 380                 


Met Val Pro Tyr Arg Asp Ser Lys Leu Thr His Leu Phe Lys Asn Tyr 
385                 390                 395                 400 


Phe Asp Gly Glu Gly Lys Val Arg Met Ile Val Cys Val Asn Pro Lys 
                405                 410                 415     


Ala Glu Asp Tyr Glu Glu Asn Leu Gln Val Met Arg Phe Ala Glu Val 
            420                 425                 430         


Thr Gln Glu Val Glu Val Ala Arg Pro Val Asp Lys Ala Ile Cys Gly 
        435                 440                 445             


Leu Thr Pro Gly Arg Arg Tyr Arg Asn Gln Pro Arg Gly Pro Val Gly 
    450                 455                 460                 


Asn Glu Pro Leu Val Thr Asp Val Val Leu Gln Ser Phe Pro Pro Leu 
465                 470                 475                 480 


Pro Ser Cys Glu Ile Leu Asp Ile Asn Asp Glu Gln Thr Leu Pro Arg 
                485                 490                 495     


Leu Ile Glu Ala Leu Glu Lys Arg His Asn Leu Arg Gln Met Met Ile 
            500                 505                 510         


Asp Glu Phe Asn Lys Gln Ser Asn Ala Phe Lys Ala Leu Leu Gln Glu 
        515                 520                 525             


Phe Asp Asn Ala Val Leu Ser Lys Glu Asn His Met Gln Gly Lys Leu 
    530                 535                 540                 


Asn Glu Lys Glu Lys Met Ile Ser Gly Gln Lys Leu Glu Ile Glu Arg 
545                 550                 555                 560 


Leu Glu Lys Lys Asn Lys Thr Leu Glu Tyr Lys Ile Glu Ile Leu Glu 
                565                 570                 575     


Lys Thr Thr Thr Ile Tyr Glu Glu Asp Lys Arg Asn Leu Gln Gln Glu 
            580                 585                 590         


Leu Glu Thr Gln Asn Gln Lys Leu Gln Arg Gln Phe Ser Asp Lys Arg 
        595                 600                 605             


Arg Leu Glu Ala Arg Leu Gln Gly Met Val Thr Glu Thr Thr Met Lys 
    610                 615                 620                 


Trp Glu Lys Glu Cys Glu Arg Arg Val Ala Ala Lys Gln Leu Glu Met 
625                 630                 635                 640 


Gln Asn Lys Leu Trp Val Lys Asp Glu Lys Leu Lys Gln Leu Lys Ala 
                645                 650                 655     


Ile Val Thr Glu Pro Lys Thr Glu Lys Pro Glu Arg Pro Ser Arg Glu 
            660                 665                 670         


Arg Asp Arg Glu Lys Val Thr Gln Arg Ser Val Ser Pro Ser Pro Val 
        675                 680                 685             


Pro Leu Ser Ser Asn Tyr Ile Ala Gln Ile Ser Asn Gly Gln Gln Leu 
    690                 695                 700                 


Met Ser Gln Pro Gln Leu His Arg Arg Ser Asn Ser Cys Ser Ser Ile 
705                 710                 715                 720 


Ser Val Ala Ser Cys Ile Ser Glu Trp Glu Gln Lys Ile Pro Thr Tyr 
                725                 730                 735     


Asn Thr Pro Leu Lys Val Thr Ser Ile Ala Arg Arg Arg Gln Gln Glu 
            740                 745                 750         


Pro Gly Gln Ser Lys Thr Cys Ile Val Ser Asp Arg Arg Arg Gly Met 
        755                 760                 765             


Tyr Trp Thr Glu Gly Arg Glu Val Val Pro Thr Phe Arg Asn Glu Ile 
    770                 775                 780                 


Glu Ile Glu Glu Asp His Cys Gly Arg Leu Leu Phe Gln Pro Asp Gln 
785                 790                 795                 800 


Asn Ala Pro Pro Ile Arg Leu Arg His Arg Arg Ser Arg Ser Ala Gly 
                805                 810                 815     


Asp Arg Trp Val Asp His Lys Pro Ala Ser Asn Met Gln Thr Glu Thr 
            820                 825                 830         


Val Met Gln Pro His Val Pro His Ala Ile Thr Val Ser Val Ala Asn 
        835                 840                 845             


Glu Lys Ala Leu Ala Lys Cys Glu Lys Tyr Met Leu Thr His Gln Glu 
    850                 855                 860                 


Leu Ala Ser Asp Gly Glu Ile Glu Thr Lys Leu Ile Lys Gly Asp Ile 
865                 870                 875                 880 


Tyr Lys Thr Arg Gly Gly Gly Gln Ser Val Gln Phe Thr Asp Ile Glu 
                885                 890                 895     


Thr Leu Lys Gln Glu Ser Pro Asn Gly Ser Arg Lys Arg Arg Ser Ser 
            900                 905                 910         


Thr Val Ala Pro Ala Gln Pro Asp Gly Ala Glu Ser Glu Trp Thr Asp 
        915                 920                 925             


Val Glu Thr Arg Cys Ser Val Ala Val Glu Met Arg Ala Gly Ser Gln 
    930                 935                 940                 


Leu Gly Pro Gly Tyr Gln His His Ala Gln Pro Lys Arg Lys Lys Pro 
945                 950                 955                 960 


<210>  3887
<211>  436
<212>  PRT
<213>  homo sapiens

<400>  3887

Met Arg Pro Gly Gly Glu Arg Pro Val Glu Gly Gly Ala Cys Asn Gly 
1               5                   10                  15      


Arg Ser Glu Leu Glu Leu Leu Lys Leu Arg Ser Ala Glu Cys Ile Asp 
            20                  25                  30          


Glu Ala Ala Glu Arg Leu Gly Ala Leu Ser Arg Ala Ile Trp Ser Gln 
        35                  40                  45              


Pro Glu Leu Ala Tyr Glu Glu His His Ala His Arg Val Leu Thr His 
    50                  55                  60                  


Phe Phe Glu Arg Glu Pro Pro Ala Ala Ser Trp Ala Val Gln Pro His 
65                  70                  75                  80  


Tyr Gln Leu Pro Thr Ala Phe Arg Ala Glu Trp Glu Pro Pro Glu Ala 
                85                  90                  95      


Arg Ala Pro Ser Ala Thr Pro Arg Pro Leu His Leu Gly Phe Leu Cys 
            100                 105                 110         


Glu Tyr Asp Ala Leu Pro Gly Ile Gly His Ala Cys Gly His Asn Leu 
        115                 120                 125             


Ile Ala Glu Val Gly Ala Ala Ala Ala Leu Gly Val Arg Gly Ala Leu 
    130                 135                 140                 


Glu Gly Leu Pro Arg Pro Pro Pro Pro Val Lys Val Val Val Leu Gly 
145                 150                 155                 160 


Thr Pro Ala Glu Glu Asp Gly Gly Gly Lys Ile Asp Leu Ile Glu Ala 
                165                 170                 175     


Gly Ala Phe Thr Asn Leu Asp Val Val Phe Met Ala His Pro Ser Gln 
            180                 185                 190         


Glu Asn Ala Ala Tyr Leu Pro Asp Met Ala Glu His Asp Val Thr Val 
        195                 200                 205             


Lys Tyr Tyr Gly Lys Ala Ser His Ser Ala Ser Tyr Pro Trp Glu Gly 
    210                 215                 220                 


Leu Asn Ala Leu Asp Ala Ala Val Leu Ala Tyr Asn Asn Leu Ser Val 
225                 230                 235                 240 


Phe Arg Gln Gln Met Lys Pro Thr Trp Arg Val His Gly Ile Ile Lys 
                245                 250                 255     


Asn Gly Gly Val Lys Pro Asn Ile Ile Pro Ser Tyr Ser Glu Leu Ile 
            260                 265                 270         


Tyr Tyr Phe Arg Ala Pro Ser Met Lys Glu Leu Gln Val Leu Thr Lys 
        275                 280                 285             


Lys Ala Glu Asp Cys Phe Arg Ala Ala Ala Leu Ala Ser Gly Cys Thr 
    290                 295                 300                 


Val Glu Ile Lys Gly Gly Ala His Asp Tyr Tyr Asn Val Leu Pro Asn 
305                 310                 315                 320 


Lys Ser Leu Trp Lys Ala Tyr Met Glu Asn Gly Arg Lys Leu Gly Ile 
                325                 330                 335     


Glu Phe Ile Ser Glu Asp Thr Met Leu Asn Gly Pro Ser Gly Ser Thr 
            340                 345                 350         


Asp Phe Gly Asn Val Ser Phe Val Val Pro Gly Ile His Pro Tyr Phe 
        355                 360                 365             


His Ile Gly Ser Asn Ala Leu Asn His Thr Glu Gln Tyr Thr Glu Ala 
    370                 375                 380                 


Ala Gly Ser Gln Glu Ala Gln Phe Tyr Thr Leu Arg Thr Ala Lys Ala 
385                 390                 395                 400 


Leu Ala Met Thr Ala Leu Asp Val Ile Phe Lys Pro Glu Leu Leu Glu 
                405                 410                 415     


Gly Ile Arg Glu Asp Phe Lys Leu Lys Leu Gln Glu Glu Gln Phe Val 
            420                 425                 430         


Asn Ala Val Glu 
        435     


<210>  3888
<211>  54
<212>  PRT
<213>  homo sapiens

<400>  3888

Met Pro Gly Lys Lys Ala Arg Lys Asn Ala Gln Pro Ser Pro Ala Arg 
1               5                   10                  15      


Ala Pro Ala Glu Leu Glu Val Glu Cys Ala Thr Gln Leu Arg Arg Phe 
            20                  25                  30          


Gly Asp Lys Leu Asn Phe Arg Gln Lys Leu Leu Asn Leu Ile Ser Lys 
        35                  40                  45              


Leu Phe Cys Ser Gly Thr 
    50                  


<210>  3889
<211>  863
<212>  PRT
<213>  homo sapiens

<400>  3889

Met Ala Arg Arg Ser Ser Phe Gln Ser Cys Gln Ile Ile Ser Leu Phe 
1               5                   10                  15      


Thr Phe Ala Val Gly Val Asn Ile Cys Leu Gly Phe Thr Ala His Arg 
            20                  25                  30          


Ile Lys Arg Ala Glu Gly Trp Glu Glu Gly Pro Pro Thr Val Leu Ser 
        35                  40                  45              


Asp Ser Pro Trp Thr Asn Ile Ser Gly Ser Cys Lys Gly Arg Cys Phe 
    50                  55                  60                  


Glu Leu Gln Glu Ala Gly Pro Pro Asp Cys Arg Cys Asp Asn Leu Cys 
65                  70                  75                  80  


Lys Ser Tyr Thr Ser Cys Cys His Asp Phe Asp Glu Leu Cys Leu Lys 
                85                  90                  95      


Thr Ala Arg Gly Trp Glu Cys Thr Lys Asp Arg Cys Gly Glu Val Arg 
            100                 105                 110         


Asn Glu Glu Asn Ala Cys His Cys Ser Glu Asp Cys Leu Ala Arg Gly 
        115                 120                 125             


Asp Cys Cys Thr Asn Tyr Gln Val Val Cys Lys Gly Glu Ser His Trp 
    130                 135                 140                 


Val Asp Asp Asp Cys Glu Glu Ile Lys Ala Ala Glu Cys Pro Ala Gly 
145                 150                 155                 160 


Phe Val Arg Pro Pro Leu Ile Ile Phe Ser Val Asp Gly Phe Arg Ala 
                165                 170                 175     


Ser Tyr Met Lys Lys Gly Ser Lys Val Met Pro Asn Ile Glu Lys Leu 
            180                 185                 190         


Arg Ser Cys Gly Thr His Ser Pro Tyr Met Arg Pro Val Tyr Pro Thr 
        195                 200                 205             


Lys Thr Phe Pro Asn Leu Tyr Thr Leu Ala Thr Gly Leu Tyr Pro Glu 
    210                 215                 220                 


Ser His Gly Ile Val Gly Asn Ser Met Tyr Asp Pro Val Phe Asp Ala 
225                 230                 235                 240 


Thr Phe His Leu Arg Gly Arg Glu Lys Phe Asn His Arg Trp Trp Gly 
                245                 250                 255     


Gly Gln Pro Leu Trp Ile Thr Ala Thr Lys Gln Gly Val Lys Ala Gly 
            260                 265                 270         


Thr Phe Phe Trp Ser Val Val Ile Pro His Glu Arg Arg Ile Leu Thr 
        275                 280                 285             


Ile Leu Gln Trp Leu Thr Leu Pro Asp His Glu Arg Pro Ser Val Tyr 
    290                 295                 300                 


Ala Phe Tyr Ser Glu Gln Pro Asp Phe Ser Gly His Lys Tyr Gly Pro 
305                 310                 315                 320 


Phe Gly Pro Glu Met Thr Asn Pro Leu Arg Glu Ile Asp Lys Ile Val 
                325                 330                 335     


Gly Gln Leu Met Asp Gly Leu Lys Gln Leu Lys Leu His Arg Cys Val 
            340                 345                 350         


Asn Val Ile Phe Val Gly Asp His Gly Met Glu Asp Val Thr Cys Asp 
        355                 360                 365             


Arg Thr Glu Phe Leu Ser Asn Tyr Leu Thr Asn Val Asp Asp Ile Thr 
    370                 375                 380                 


Leu Val Pro Gly Thr Leu Gly Arg Ile Arg Ser Lys Phe Ser Asn Asn 
385                 390                 395                 400 


Ala Lys Tyr Asp Pro Lys Ala Ile Ile Ala Asn Leu Thr Cys Lys Lys 
                405                 410                 415     


Pro Asp Gln His Phe Lys Pro Tyr Leu Lys Gln His Leu Pro Lys Arg 
            420                 425                 430         


Leu His Tyr Ala Asn Asn Arg Arg Ile Glu Asp Ile His Leu Leu Val 
        435                 440                 445             


Glu Arg Arg Trp His Val Ala Arg Lys Pro Leu Asp Val Tyr Lys Lys 
    450                 455                 460                 


Pro Ser Gly Lys Cys Phe Phe Gln Gly Asp His Gly Phe Asp Asn Lys 
465                 470                 475                 480 


Val Asn Ser Met Gln Thr Val Phe Val Gly Tyr Gly Ser Thr Phe Lys 
                485                 490                 495     


Tyr Lys Thr Lys Val Pro Pro Phe Glu Asn Ile Glu Leu Tyr Asn Val 
            500                 505                 510         


Met Cys Asp Leu Leu Gly Leu Lys Pro Ala Pro Asn Asn Gly Thr His 
        515                 520                 525             


Gly Ser Leu Asn His Leu Leu Arg Thr Asn Thr Phe Arg Pro Thr Met 
    530                 535                 540                 


Pro Glu Glu Val Thr Arg Pro Asn Tyr Pro Gly Ile Met Tyr Leu Gln 
545                 550                 555                 560 


Ser Asp Phe Asp Leu Gly Cys Thr Cys Asp Asp Lys Val Glu Pro Lys 
                565                 570                 575     


Asn Lys Leu Asp Glu Leu Asn Lys Arg Leu His Thr Lys Gly Ser Thr 
            580                 585                 590         


Glu Glu Arg His Leu Leu Tyr Gly Arg Pro Ala Val Leu Tyr Arg Thr 
        595                 600                 605             


Arg Tyr Asp Ile Leu Tyr His Thr Asp Phe Glu Ser Gly Tyr Ser Glu 
    610                 615                 620                 


Ile Phe Leu Met Pro Leu Trp Thr Ser Tyr Thr Val Ser Lys Gln Ala 
625                 630                 635                 640 


Glu Val Ser Ser Val Pro Asp His Leu Thr Ser Cys Val Arg Pro Asp 
                645                 650                 655     


Val Arg Val Ser Pro Ser Phe Ser Gln Asn Cys Leu Ala Tyr Lys Asn 
            660                 665                 670         


Asp Lys Gln Met Ser Tyr Gly Phe Leu Phe Pro Pro Tyr Leu Ser Ser 
        675                 680                 685             


Ser Pro Glu Ala Lys Tyr Asp Ala Phe Leu Val Thr Asn Met Val Pro 
    690                 695                 700                 


Met Tyr Pro Ala Phe Lys Arg Val Trp Asn Tyr Phe Gln Arg Val Leu 
705                 710                 715                 720 


Val Lys Lys Tyr Ala Ser Glu Arg Asn Gly Val Asn Val Ile Ser Gly 
                725                 730                 735     


Pro Ile Phe Asp Tyr Asp Tyr Asp Gly Leu His Asp Thr Glu Asp Lys 
            740                 745                 750         


Ile Lys Gln Tyr Val Glu Gly Ser Ser Ile Pro Val Pro Thr His Tyr 
        755                 760                 765             


Tyr Ser Ile Ile Thr Ser Cys Leu Asp Phe Thr Gln Pro Ala Asp Lys 
    770                 775                 780                 


Cys Asp Gly Pro Leu Ser Val Ser Ser Phe Ile Leu Pro His Arg Pro 
785                 790                 795                 800 


Asp Asn Glu Glu Ser Cys Asn Ser Ser Glu Asp Glu Ser Lys Trp Val 
                805                 810                 815     


Glu Glu Leu Met Lys Met His Thr Ala Arg Val Arg Asp Ile Glu His 
            820                 825                 830         


Leu Thr Ser Leu Asp Phe Phe Arg Lys Thr Ser Arg Ser Tyr Pro Glu 
        835                 840                 845             


Ile Leu Thr Leu Lys Thr Tyr Leu His Thr Tyr Glu Ser Glu Ile 
    850                 855                 860             


<210>  3890
<211>  888
<212>  PRT
<213>  homo sapiens

<400>  3890

Met Ala Arg Arg Ser Ser Phe Gln Ser Cys Gln Ile Ile Ser Leu Phe 
1               5                   10                  15      


Thr Phe Ala Val Gly Val Asn Ile Cys Leu Gly Phe Thr Ala His Arg 
            20                  25                  30          


Ile Lys Arg Ala Glu Gly Trp Glu Glu Gly Pro Pro Thr Val Leu Ser 
        35                  40                  45              


Asp Ser Pro Trp Thr Asn Ile Ser Gly Ser Cys Lys Gly Arg Cys Phe 
    50                  55                  60                  


Glu Leu Gln Glu Ala Gly Pro Pro Asp Cys Arg Cys Asp Asn Leu Cys 
65                  70                  75                  80  


Lys Ser Tyr Thr Ser Cys Cys His Asp Phe Asp Glu Leu Cys Leu Lys 
                85                  90                  95      


Thr Ala Arg Gly Trp Glu Cys Thr Lys Asp Arg Cys Gly Glu Val Arg 
            100                 105                 110         


Asn Glu Glu Asn Ala Cys His Cys Ser Glu Asp Cys Leu Ala Arg Gly 
        115                 120                 125             


Asp Cys Cys Thr Asn Tyr Gln Val Val Cys Lys Gly Glu Ser His Trp 
    130                 135                 140                 


Val Asp Asp Asp Cys Glu Glu Ile Lys Ala Ala Glu Cys Pro Ala Gly 
145                 150                 155                 160 


Phe Val Arg Pro Pro Leu Ile Ile Phe Ser Val Asp Gly Phe Arg Ala 
                165                 170                 175     


Ser Tyr Met Lys Lys Gly Ser Lys Val Met Pro Asn Ile Glu Lys Leu 
            180                 185                 190         


Arg Ser Cys Gly Thr His Ser Pro Tyr Met Arg Pro Val Tyr Pro Thr 
        195                 200                 205             


Lys Thr Phe Pro Asn Leu Tyr Thr Leu Ala Thr Gly Leu Tyr Pro Glu 
    210                 215                 220                 


Ser His Gly Ile Val Gly Asn Ser Met Tyr Asp Pro Val Phe Asp Ala 
225                 230                 235                 240 


Thr Phe His Leu Arg Gly Arg Glu Lys Phe Asn His Arg Trp Trp Gly 
                245                 250                 255     


Gly Gln Pro Leu Trp Ile Thr Ala Thr Lys Gln Gly Val Lys Ala Gly 
            260                 265                 270         


Thr Phe Phe Trp Ser Val Val Ile Pro His Glu Arg Arg Ile Leu Thr 
        275                 280                 285             


Ile Leu Gln Trp Leu Thr Leu Pro Asp His Glu Arg Pro Ser Val Tyr 
    290                 295                 300                 


Ala Phe Tyr Ser Glu Gln Pro Asp Phe Ser Gly His Lys Tyr Gly Pro 
305                 310                 315                 320 


Phe Gly Pro Glu Met Thr Asn Pro Leu Arg Glu Ile Asp Lys Ile Val 
                325                 330                 335     


Gly Gln Leu Met Asp Gly Leu Lys Gln Leu Lys Leu His Arg Cys Val 
            340                 345                 350         


Asn Val Ile Phe Val Gly Asp His Gly Met Glu Asp Val Thr Cys Asp 
        355                 360                 365             


Arg Thr Glu Phe Leu Ser Asn Tyr Leu Thr Asn Val Asp Asp Ile Thr 
    370                 375                 380                 


Leu Val Pro Gly Thr Leu Gly Arg Ile Arg Ser Lys Phe Ser Asn Asn 
385                 390                 395                 400 


Ala Lys Tyr Asp Pro Lys Ala Ile Ile Ala Asn Leu Thr Cys Lys Lys 
                405                 410                 415     


Pro Asp Gln His Phe Lys Pro Tyr Leu Lys Gln His Leu Pro Lys Arg 
            420                 425                 430         


Leu His Tyr Ala Asn Asn Arg Arg Ile Glu Asp Ile His Leu Leu Val 
        435                 440                 445             


Glu Arg Arg Trp His Val Ala Arg Lys Pro Leu Asp Val Tyr Lys Lys 
    450                 455                 460                 


Pro Ser Gly Lys Cys Phe Phe Gln Gly Asp His Gly Phe Asp Asn Lys 
465                 470                 475                 480 


Val Asn Ser Met Gln Thr Val Phe Val Gly Tyr Gly Ser Thr Phe Lys 
                485                 490                 495     


Tyr Lys Thr Lys Val Pro Pro Phe Glu Asn Ile Glu Leu Tyr Asn Val 
            500                 505                 510         


Met Cys Asp Leu Leu Gly Leu Lys Pro Ala Pro Asn Asn Gly Thr His 
        515                 520                 525             


Gly Ser Leu Asn His Leu Leu Arg Thr Asn Thr Phe Arg Pro Thr Met 
    530                 535                 540                 


Pro Glu Glu Val Thr Arg Pro Asn Tyr Pro Gly Ile Met Tyr Leu Gln 
545                 550                 555                 560 


Ser Asp Phe Asp Leu Gly Cys Thr Cys Asp Asp Lys Val Glu Pro Lys 
                565                 570                 575     


Asn Lys Leu Asp Glu Leu Asn Lys Arg Leu His Thr Lys Gly Ser Thr 
            580                 585                 590         


Glu Ala Glu Thr Arg Lys Phe Arg Gly Ser Arg Asn Glu Asn Lys Glu 
        595                 600                 605             


Asn Ile Asn Gly Asn Phe Glu Pro Arg Lys Glu Arg His Leu Leu Tyr 
    610                 615                 620                 


Gly Arg Pro Ala Val Leu Tyr Arg Thr Arg Tyr Asp Ile Leu Tyr His 
625                 630                 635                 640 


Thr Asp Phe Glu Ser Gly Tyr Ser Glu Ile Phe Leu Met Pro Leu Trp 
                645                 650                 655     


Thr Ser Tyr Thr Val Ser Lys Gln Ala Glu Val Ser Ser Val Pro Asp 
            660                 665                 670         


His Leu Thr Ser Cys Val Arg Pro Asp Val Arg Val Ser Pro Ser Phe 
        675                 680                 685             


Ser Gln Asn Cys Leu Ala Tyr Lys Asn Asp Lys Gln Met Ser Tyr Gly 
    690                 695                 700                 


Phe Leu Phe Pro Pro Tyr Leu Ser Ser Ser Pro Glu Ala Lys Tyr Asp 
705                 710                 715                 720 


Ala Phe Leu Val Thr Asn Met Val Pro Met Tyr Pro Ala Phe Lys Arg 
                725                 730                 735     


Val Trp Asn Tyr Phe Gln Arg Val Leu Val Lys Lys Tyr Ala Ser Glu 
            740                 745                 750         


Arg Asn Gly Val Asn Val Ile Ser Gly Pro Ile Phe Asp Tyr Asp Tyr 
        755                 760                 765             


Asp Gly Leu His Asp Thr Glu Asp Lys Ile Lys Gln Tyr Val Glu Gly 
    770                 775                 780                 


Ser Ser Ile Pro Val Pro Thr His Tyr Tyr Ser Ile Ile Thr Ser Cys 
785                 790                 795                 800 


Leu Asp Phe Thr Gln Pro Ala Asp Lys Cys Asp Gly Pro Leu Ser Val 
                805                 810                 815     


Ser Ser Phe Ile Leu Pro His Arg Pro Asp Asn Glu Glu Ser Cys Asn 
            820                 825                 830         


Ser Ser Glu Asp Glu Ser Lys Trp Val Glu Glu Leu Met Lys Met His 
        835                 840                 845             


Thr Ala Arg Val Arg Asp Ile Glu His Leu Thr Ser Leu Asp Phe Phe 
    850                 855                 860                 


Arg Lys Thr Ser Arg Ser Tyr Pro Glu Ile Leu Thr Leu Lys Thr Tyr 
865                 870                 875                 880 


Leu His Thr Tyr Glu Ser Glu Ile 
                885             


<210>  3891
<211>  1539
<212>  PRT
<213>  homo sapiens

<400>  3891

Met Asp Ser Tyr Phe Lys Ala Ala Val Ser Asp Leu Asp Lys Leu Leu 
1               5                   10                  15      


Asp Asp Phe Glu Gln Asn Pro Asp Glu Gln Asp Tyr Leu Gln Asp Val 
            20                  25                  30          


Gln Asn Ala Tyr Asp Ser Asn His Cys Ser Val Ser Ser Glu Leu Ala 
        35                  40                  45              


Ser Ser Gln Arg Thr Ser Leu Leu Pro Lys Asp Gln Glu Cys Val Asn 
    50                  55                  60                  


Ser Cys Ala Ser Ser Glu Thr Ser Tyr Gly Thr Asn Glu Ser Ser Leu 
65                  70                  75                  80  


Asn Glu Lys Thr Leu Lys Gly Leu Thr Ser Ile Gln Asn Glu Lys Asn 
                85                  90                  95      


Val Thr Gly Leu Asp Leu Leu Ser Ser Val Asp Gly Gly Thr Ser Asp 
            100                 105                 110         


Glu Ile Gln Pro Leu Tyr Met Gly Arg Cys Ser Lys Pro Ile Cys Asp 
        115                 120                 125             


Leu Ile Ser Asp Met Gly Asn Leu Val His Ala Thr Asn Ser Glu Glu 
    130                 135                 140                 


Asp Ile Lys Lys Leu Leu Pro Asp Asp Phe Lys Ser Asn Ala Asp Ser 
145                 150                 155                 160 


Leu Ile Gly Leu Asp Leu Ser Ser Val Ser Asp Thr Pro Cys Val Ser 
                165                 170                 175     


Ser Thr Asp His Asp Ser Asp Thr Val Arg Glu Gln Gln Asn Asp Ile 
            180                 185                 190         


Ser Ser Glu Leu Gln Asn Arg Glu Ile Gly Gly Ile Lys Glu Leu Gly 
        195                 200                 205             


Ile Lys Val Asp Thr Thr Leu Ser Asp Ser Tyr Asn Tyr Ser Gly Thr 
    210                 215                 220                 


Glu Asn Leu Lys Asp Lys Lys Ile Phe Asn Gln Leu Glu Ser Ile Val 
225                 230                 235                 240 


Asp Phe Asn Met Ser Ser Ala Leu Thr Arg Gln Ser Ser Lys Met Phe 
                245                 250                 255     


His Ala Lys Asp Lys Leu Gln His Lys Ser Gln Pro Cys Gly Leu Leu 
            260                 265                 270         


Lys Asp Val Gly Leu Val Lys Glu Glu Val Asp Val Ala Val Ile Thr 
        275                 280                 285             


Ala Ala Glu Cys Leu Lys Glu Glu Gly Lys Thr Ser Ala Leu Thr Cys 
    290                 295                 300                 


Ser Leu Pro Lys Asn Glu Asp Leu Cys Leu Asn Asp Ser Asn Ser Arg 
305                 310                 315                 320 


Asp Glu Asn Phe Lys Leu Pro Asp Phe Ser Phe Gln Glu Asp Lys Thr 
                325                 330                 335     


Val Ile Lys Gln Ser Ala Gln Glu Asp Ser Lys Ser Leu Asp Leu Lys 
            340                 345                 350         


Asp Asn Asp Val Ile Gln Asp Ser Ser Ser Ala Leu His Val Ser Ser 
        355                 360                 365             


Lys Asp Val Pro Ser Ser Leu Ser Cys Leu Pro Ala Ser Gly Ser Met 
    370                 375                 380                 


Cys Gly Ser Leu Ile Glu Ser Lys Ala Arg Gly Asp Phe Leu Pro Gln 
385                 390                 395                 400 


His Glu His Lys Asp Asn Ile Gln Asp Ala Val Thr Ile His Glu Glu 
                405                 410                 415     


Ile Gln Asn Ser Val Val Leu Gly Gly Glu Pro Phe Lys Glu Asn Asp 
            420                 425                 430         


Leu Leu Lys Gln Glu Lys Cys Lys Ser Ile Leu Leu Gln Ser Leu Ile 
        435                 440                 445             


Glu Gly Met Glu Asp Arg Lys Ile Asp Pro Asp Gln Thr Val Ile Arg 
    450                 455                 460                 


Ala Glu Ser Leu Asp Gly Gly Asp Thr Ser Ser Thr Val Val Glu Ser 
465                 470                 475                 480 


Gln Glu Gly Leu Ser Gly Thr His Val Pro Glu Ser Ser Asp Cys Cys 
                485                 490                 495     


Glu Gly Phe Ile Asn Thr Phe Ser Ser Asn Asp Met Asp Gly Gln Asp 
            500                 505                 510         


Leu Asp Tyr Phe Asn Ile Asp Glu Gly Ala Lys Ser Gly Pro Leu Ile 
        515                 520                 525             


Ser Asp Ala Glu Leu Asp Ala Phe Leu Thr Glu Gln Tyr Leu Gln Thr 
    530                 535                 540                 


Thr Asn Ile Lys Ser Phe Glu Glu Asn Val Asn Asp Ser Lys Ser Gln 
545                 550                 555                 560 


Met Asn Gln Ile Asp Met Lys Gly Leu Asp Asp Gly Asn Ile Asn Asn 
                565                 570                 575     


Ile Tyr Phe Asn Ala Glu Ala Gly Ala Ile Gly Glu Ser His Gly Ile 
            580                 585                 590         


Asn Ile Ile Cys Glu Thr Val Asp Lys Gln Asn Thr Ile Glu Asn Gly 
        595                 600                 605             


Leu Ser Leu Gly Glu Lys Ser Thr Ile Pro Val Gln Gln Gly Leu Pro 
    610                 615                 620                 


Thr Ser Lys Ser Glu Ile Thr Asn Gln Leu Ser Val Ser Asp Ile Asn 
625                 630                 635                 640 


Ser Gln Ser Val Gly Gly Ala Arg Pro Lys Gln Leu Phe Ser Leu Pro 
                645                 650                 655     


Ser Arg Thr Arg Ser Ser Lys Asp Leu Asn Lys Pro Asp Val Pro Asp 
            660                 665                 670         


Thr Ile Glu Ser Glu Pro Ser Thr Ala Asp Thr Val Val Pro Ile Thr 
        675                 680                 685             


Cys Ala Ile Asp Ser Thr Ala Asp Pro Gln Val Ser Phe Asn Ser Asn 
    690                 695                 700                 


Tyr Ile Asp Ile Glu Ser Asn Ser Glu Gly Gly Ser Ser Phe Val Thr 
705                 710                 715                 720 


Ala Asn Glu Asp Ser Val Pro Glu Asn Thr Cys Lys Glu Gly Leu Val 
                725                 730                 735     


Leu Gly Gln Lys Gln Pro Thr Trp Val Pro Asp Ser Glu Ala Pro Asn 
            740                 745                 750         


Cys Met Asn Cys Gln Val Lys Phe Thr Phe Thr Lys Arg Arg His His 
        755                 760                 765             


Cys Arg Ala Cys Gly Lys Val Phe Cys Gly Val Cys Cys Asn Arg Lys 
    770                 775                 780                 


Cys Lys Leu Gln Tyr Leu Glu Lys Glu Ala Arg Val Cys Val Val Cys 
785                 790                 795                 800 


Tyr Glu Thr Ile Ser Lys Ala Gln Ala Phe Glu Arg Met Met Ser Pro 
                805                 810                 815     


Thr Gly Ser Asn Leu Lys Ser Asn His Ser Asp Glu Cys Thr Thr Val 
            820                 825                 830         


Gln Pro Pro Gln Glu Asn Gln Thr Ser Ser Ile Pro Ser Pro Ala Thr 
        835                 840                 845             


Leu Pro Val Ser Ala Leu Lys Gln Pro Gly Val Glu Gly Leu Cys Ser 
    850                 855                 860                 


Lys Glu Gln Lys Arg Val Trp Phe Ala Asp Gly Ile Leu Pro Asn Gly 
865                 870                 875                 880 


Glu Val Ala Asp Thr Thr Lys Leu Ser Ser Gly Ser Lys Arg Cys Ser 
                885                 890                 895     


Glu Asp Phe Ser Pro Leu Ser Pro Asp Val Pro Met Thr Val Asn Thr 
            900                 905                 910         


Val Asp His Ser His Ser Thr Thr Val Glu Lys Pro Asn Asn Glu Thr 
        915                 920                 925             


Gly Asp Ile Thr Arg Asn Glu Ile Ile Gln Ser Pro Ile Ser Gln Val 
    930                 935                 940                 


Pro Ser Val Glu Lys Leu Ser Met Asn Thr Gly Asn Glu Gly Leu Pro 
945                 950                 955                 960 


Thr Ser Gly Ser Phe Thr Leu Asp Asp Asp Val Phe Ala Glu Thr Glu 
                965                 970                 975     


Glu Pro Ser Ser Pro Thr Gly Val Leu Val Asn Ser Asn Leu Pro Ile 
            980                 985                 990         


Ala Ser Ile Ser Asp Tyr Arg Leu  Leu Cys Asp Ile Asn  Lys Tyr Val 
        995                 1000                 1005             


Cys Asn  Lys Ile Ser Leu Leu  Pro Asn Asp Glu Asp  Ser Leu Pro 
    1010                 1015                 1020             


Pro Leu  Leu Val Ala Ser Gly  Glu Lys Gly Ser Val  Pro Val Val 
    1025                 1030                 1035             


Glu Glu  His Pro Ser His Glu  Gln Ile Ile Leu Leu  Leu Glu Gly 
    1040                 1045                 1050             


Glu Gly  Phe His Pro Val Thr  Phe Val Leu Asn Ala  Asn Leu Leu 
    1055                 1060                 1065             


Val Asn  Val Lys Phe Ile Phe  Tyr Ser Ser Asp Lys  Tyr Trp Tyr 
    1070                 1075                 1080             


Phe Ser  Thr Asn Gly Leu His  Gly Leu Gly Gln Ala  Glu Ile Ile 
    1085                 1090                 1095             


Ile Leu  Leu Leu Cys Leu Pro  Asn Glu Asp Thr Ile  Pro Lys Asp 
    1100                 1105                 1110             


Ile Phe  Arg Leu Phe Ile Thr  Ile Tyr Lys Asp Ala  Leu Lys Gly 
    1115                 1120                 1125             


Lys Tyr  Ile Glu Asn Leu Asp  Asn Ile Thr Phe Thr  Glu Ser Phe 
    1130                 1135                 1140             


Leu Ser  Ser Lys Asp His Gly  Gly Phe Leu Phe Ile  Thr Pro Thr 
    1145                 1150                 1155             


Phe Gln  Lys Leu Asp Asp Leu  Ser Leu Pro Ser Asn  Pro Phe Leu 
    1160                 1165                 1170             


Cys Gly  Ile Leu Ile Gln Lys  Leu Glu Ile Pro Trp  Ala Lys Val 
    1175                 1180                 1185             


Phe Pro  Met Arg Leu Met Leu  Arg Leu Gly Ala Glu  Tyr Lys Ala 
    1190                 1195                 1200             


Tyr Pro  Ala Pro Leu Thr Ser  Ile Arg Gly Arg Lys  Pro Leu Phe 
    1205                 1210                 1215             


Gly Glu  Ile Gly His Thr Ile  Met Asn Leu Leu Val  Asp Leu Arg 
    1220                 1225                 1230             


Asn Tyr  Gln Tyr Thr Leu His  Asn Ile Asp Gln Leu  Leu Ile His 
    1235                 1240                 1245             


Met Glu  Met Gly Lys Ser Cys  Ile Lys Ile Pro Arg  Lys Lys Tyr 
    1250                 1255                 1260             


Ser Asp  Val Met Lys Val Leu  Asn Ser Ser Asn Glu  His Val Ile 
    1265                 1270                 1275             


Ser Ile  Gly Ala Ser Phe Ser  Thr Glu Ala Asp Ser  His Leu Val 
    1280                 1285                 1290             


Cys Ile  Gln Asn Asp Gly Ile  Tyr Glu Thr Gln Ala  Asn Ser Ala 
    1295                 1300                 1305             


Thr Gly  His Pro Arg Lys Val  Thr Gly Ala Ser Phe  Val Val Phe 
    1310                 1315                 1320             


Asn Gly  Ala Leu Lys Thr Ser  Ser Gly Phe Leu Ala  Lys Ser Ser 
    1325                 1330                 1335             


Ile Val  Glu Asp Gly Leu Met  Val Gln Ile Thr Pro  Glu Thr Met 
    1340                 1345                 1350             


Asn Gly  Leu Arg Leu Ala Leu  Arg Glu Gln Lys Asp  Phe Lys Ile 
    1355                 1360                 1365             


Thr Cys  Gly Lys Val Asp Ala  Val Asp Leu Arg Glu  Tyr Val Asp 
    1370                 1375                 1380             


Ile Cys  Trp Val Asp Ala Glu  Glu Lys Gly Asn Lys  Gly Val Ile 
    1385                 1390                 1395             


Ser Ser  Val Asp Gly Ile Ser  Leu Gln Gly Phe Pro  Ser Glu Lys 
    1400                 1405                 1410             


Ile Lys  Leu Glu Ala Asp Phe  Glu Thr Asp Glu Lys  Ile Val Lys 
    1415                 1420                 1425             


Cys Thr  Glu Val Phe Tyr Phe  Leu Lys Asp Gln Asp  Leu Ser Ile 
    1430                 1435                 1440             


Leu Ser  Thr Ser Tyr Gln Phe  Ala Lys Glu Ile Ala  Met Ala Cys 
    1445                 1450                 1455             


Ser Ala  Ala Leu Cys Pro His  Leu Lys Thr Leu Lys  Ser Asn Gly 
    1460                 1465                 1470             


Met Asn  Lys Ile Gly Leu Arg  Val Ser Ile Asp Thr  Asp Met Val 
    1475                 1480                 1485             


Glu Phe  Gln Ala Gly Ser Glu  Gly Gln Leu Leu Pro  Gln His Tyr 
    1490                 1495                 1500             


Leu Asn  Asp Leu Asp Ser Ala  Leu Ile Pro Val Ile  His Gly Gly 
    1505                 1510                 1515             


Thr Ser  Asn Ser Ser Leu Pro  Leu Glu Ile Glu Leu  Val Phe Phe 
    1520                 1525                 1530             


Ile Ile  Glu His Leu Phe 
    1535                 


<210>  3892
<211>  332
<212>  PRT
<213>  homo sapiens

<400>  3892

Met Phe Ser Glu Glu Leu Trp Leu Glu Asn Glu Lys Lys Cys Ala Val 
1               5                   10                  15      


Val Arg Lys Ser Lys Gln Gly Arg Lys Arg Gln Glu Leu Leu Ala Val 
            20                  25                  30          


Ala Phe Gly Val Lys Val Gly Val Lys Gly Gly Phe Leu Trp Pro Pro 
        35                  40                  45              


Leu Lys Leu Phe Ala Cys Ser Gln Ile Ser Ser Leu Val Arg Arg Ala 
    50                  55                  60                  


Ala Leu Thr His Asn Asp Asn His Phe Asn Tyr Glu Lys Thr His Asn 
65                  70                  75                  80  


Phe Lys Val His Thr Phe Arg Gly Pro His Trp Cys Glu Tyr Cys Ala 
                85                  90                  95      


Asn Phe Met Trp Gly Leu Ile Ala Gln Gly Val Arg Cys Ser Asp Cys 
            100                 105                 110         


Gly Leu Asn Val His Lys Gln Cys Ser Lys His Val Pro Asn Asp Cys 
        115                 120                 125             


Gln Pro Asp Leu Lys Arg Ile Lys Lys Val Tyr Cys Cys Asp Leu Thr 
    130                 135                 140                 


Thr Leu Val Lys Ala His Asn Thr Gln Arg Pro Met Val Val Asp Ile 
145                 150                 155                 160 


Cys Ile Arg Glu Ile Glu Ala Arg Gly Leu Lys Ser Glu Gly Leu Tyr 
                165                 170                 175     


Arg Val Ser Gly Phe Thr Glu His Ile Glu Asp Val Lys Met Ala Phe 
            180                 185                 190         


Asp Arg Asp Gly Glu Lys Ala Asp Ile Ser Ala Asn Val Tyr Pro Asp 
        195                 200                 205             


Ile Asn Ile Ile Thr Gly Ala Leu Lys Leu Tyr Phe Arg Asp Leu Pro 
    210                 215                 220                 


Ile Pro Val Ile Thr Tyr Asp Thr Tyr Ser Lys Phe Ile Asp Ala Ala 
225                 230                 235                 240 


Lys Ile Ser Asn Ala Asp Glu Arg Leu Glu Ala Val His Glu Val Leu 
                245                 250                 255     


Met Leu Leu Pro Pro Ala His Tyr Glu Thr Leu Arg Tyr Leu Met Ile 
            260                 265                 270         


His Leu Lys Lys Val Thr Met Asn Glu Lys Asp Asn Phe Met Asn Ala 
        275                 280                 285             


Glu Asn Leu Gly Ile Val Phe Gly Pro Thr Leu Met Arg Pro Pro Glu 
    290                 295                 300                 


Asp Ser Thr Leu Thr Thr Leu His Asp Met Arg Tyr Gln Lys Leu Ile 
305                 310                 315                 320 


Val Gln Ile Leu Ile Glu Asn Glu Asp Val Leu Phe 
                325                 330         


<210>  3893
<211>  824
<212>  PRT
<213>  homo sapiens

<400>  3893

Met Tyr Ser Asn Glu Asp Ser Arg Gln Thr Ile Val Tyr Ser Glu Glu 
1               5                   10                  15      


Ser Asn Thr Thr Met Ser Tyr Thr Gln Lys Ile Thr Asn Pro Leu Pro 
            20                  25                  30          


Ala Ala Ser Ser Thr Asp Pro Ala Pro Phe Ala Asn Ile Asn Thr Pro 
        35                  40                  45              


Val Leu Gln Glu Asp Tyr Arg Gln Asp Ser Gln Thr Arg Arg Ile Ser 
    50                  55                  60                  


Thr Leu Lys Leu Thr His Asn Gln Asp Leu Gly Ser Ser Ser Pro Ile 
65                  70                  75                  80  


Ser Thr Pro Gln Phe Ser Lys Ser Val Glu Val Pro Ser Phe Leu Lys 
                85                  90                  95      


Arg Pro Arg Ser Leu Thr Pro Asn Pro Val Pro Glu Thr His Thr Ala 
            100                 105                 110         


Ser Leu Ser Ile Gln Ile Ala Pro Leu Ser Gly Gln Asp Leu Glu Ser 
        115                 120                 125             


His Lys Gln Leu Pro Glu Leu Ser Pro Glu Thr Ala Lys Ile Pro Leu 
    130                 135                 140                 


Gln Gln Glu Arg Gln Lys Ser Ala Val Ala Ala Ala Ser Gln Ser Ser 
145                 150                 155                 160 


Asp Cys Arg Val Ser Gln Ile Thr Val Asn Gly Asn Ser Gly Gly Ala 
                165                 170                 175     


Val Ser Pro Met Ser Tyr Tyr Gln Arg Pro Phe Ser Pro Ser Ala Tyr 
            180                 185                 190         


Ser Leu Pro Ala Ser Leu Asn Ser Ser Ile Val Met Gln His Gly Thr 
        195                 200                 205             


Ser Leu Asp Ser Thr Asp Thr Tyr Pro Gln His Ala Gln Ser Leu Asp 
    210                 215                 220                 


Gly Thr Thr Ser Ser Ser Ile Pro Leu Tyr Arg Ser Ser Glu Glu Glu 
225                 230                 235                 240 


Lys Arg Val Thr Val Ile Lys Ala Pro His Tyr Pro Gly Ile Gly Pro 
                245                 250                 255     


Val Asp Glu Ser Gly Ile Pro Thr Ala Ile Arg Thr Thr Val Asp Arg 
            260                 265                 270         


Pro Lys Asp Trp Tyr Lys Thr Met Phe Lys Gln Ile His Met Val His 
        275                 280                 285             


Lys Pro Asp Asp Asp Thr Asp Met Tyr Asn Thr Pro Tyr Thr Tyr Asn 
    290                 295                 300                 


Ala Gly Leu Tyr Asn Pro Pro Tyr Ser Ala Gln Ser His Pro Ala Ala 
305                 310                 315                 320 


Lys Thr Gln Thr Tyr Arg Pro Leu Ser Lys Ser His Ser Asp Asn Ser 
                325                 330                 335     


Pro Asn Ala Phe Lys Asp Ala Ser Ser Pro Val Pro Pro Pro His Val 
            340                 345                 350         


Pro Pro Pro Val Pro Pro Leu Arg Pro Arg Asp Arg Ser Ser Thr Glu 
        355                 360                 365             


Lys His Asp Trp Asp Pro Pro Asp Arg Lys Val Asp Thr Arg Lys Phe 
    370                 375                 380                 


Arg Ser Glu Pro Arg Ser Ile Phe Glu Tyr Glu Pro Gly Lys Ser Ser 
385                 390                 395                 400 


Ile Leu Gln His Glu Arg Pro Pro Pro Leu Pro Thr Thr Pro Thr Pro 
                405                 410                 415     


Val Pro Arg Glu Pro Gly Arg Lys Pro Leu Ser Ser Ser Arg Leu Gly 
            420                 425                 430         


Glu Val Thr Gly Ser Pro Ser Pro Pro Pro Arg Ser Gly Ala Pro Thr 
        435                 440                 445             


Pro Ser Ser Arg Ala Pro Ala Leu Ser Pro Thr Arg Pro Pro Lys Lys 
    450                 455                 460                 


Pro Leu Asp Tyr Val Gln Asp His Ser Ser Gly Val Phe Asn Glu Ala 
465                 470                 475                 480 


Ser Leu Tyr Gln Ser Ser Ile Asp Arg Ser Leu Glu Arg Pro Met Ser 
                485                 490                 495     


Ser Ala Ser Met Ala Ser Asp Phe Arg Lys Arg Arg Lys Ser Glu Pro 
            500                 505                 510         


Ala Val Gly Pro Pro Arg Gly Leu Gly Asp Gln Ser Ala Ser Arg Thr 
        515                 520                 525             


Ser Pro Gly Arg Val Asp Leu Pro Gly Ser Ser Thr Thr Leu Thr Lys 
    530                 535                 540                 


Ser Phe Thr Ser Ser Ser Pro Ser Ser Pro Ser Arg Ala Lys Asp Arg 
545                 550                 555                 560 


Glu Ser Pro Arg Ser Tyr Ser Ser Thr Leu Thr Asp Met Gly Arg Ser 
                565                 570                 575     


Ala Pro Arg Glu Arg Arg Gly Thr Pro Glu Lys Glu Lys Leu Pro Ala 
            580                 585                 590         


Lys Ala Val Tyr Asp Phe Lys Ala Gln Thr Ser Lys Glu Leu Ser Phe 
        595                 600                 605             


Lys Lys Gly Asp Thr Val Tyr Ile Leu Arg Lys Ile Asp Gln Asn Trp 
    610                 615                 620                 


Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe Pro Ile Ser Tyr 
625                 630                 635                 640 


Val Glu Lys Leu Thr Pro Pro Glu Lys Ala Gln Pro Ala Arg Pro Pro 
                645                 650                 655     


Pro Pro Ala Gln Pro Gly Glu Ile Gly Glu Ala Ile Ala Lys Tyr Asn 
            660                 665                 670         


Phe Asn Ala Asp Thr Asn Val Glu Leu Ser Leu Arg Lys Gly Asp Arg 
        675                 680                 685             


Val Ile Leu Leu Lys Arg Val Asp Gln Asn Trp Tyr Glu Gly Lys Ile 
    690                 695                 700                 


Pro Gly Thr Asn Arg Gln Gly Ile Phe Pro Val Ser Tyr Val Glu Val 
705                 710                 715                 720 


Val Lys Lys Asn Thr Lys Gly Ala Glu Asp Tyr Pro Asp Pro Pro Ile 
                725                 730                 735     


Pro His Ser Tyr Ser Ser Asp Arg Ile His Ser Leu Ser Ser Asn Lys 
            740                 745                 750         


Pro Gln Arg Pro Val Phe Thr His Glu Asn Ile Gln Gly Gly Gly Glu 
        755                 760                 765             


Pro Phe Gln Ala Leu Tyr Asn Tyr Thr Pro Arg Asn Glu Asp Glu Leu 
    770                 775                 780                 


Glu Leu Arg Glu Ser Asp Val Ile Asp Val Met Glu Lys Cys Asp Asp 
785                 790                 795                 800 


Gly Trp Phe Val Gly Thr Ser Arg Arg Thr Lys Phe Phe Gly Thr Phe 
                805                 810                 815     


Pro Gly Asn Tyr Val Lys Arg Leu 
            820                 


<210>  3894
<211>  1004
<212>  PRT
<213>  homo sapiens

<400>  3894

Met Lys Ala Thr Thr Pro Leu Gln Thr Val Asp Arg Pro Lys Asp Trp 
1               5                   10                  15      


Tyr Lys Thr Met Phe Lys Gln Ile His Met Val His Lys Pro Gly Leu 
            20                  25                  30          


Tyr Asn Pro Pro Tyr Ser Ala Gln Ser His Pro Ala Ala Lys Thr Gln 
        35                  40                  45              


Thr Tyr Arg Pro Leu Ser Lys Ser His Ser Asp Asn Ser Pro Asn Ala 
    50                  55                  60                  


Phe Lys Asp Ala Ser Ser Pro Val Pro Pro Pro His Val Pro Pro Pro 
65                  70                  75                  80  


Val Pro Pro Leu Arg Pro Arg Asp Arg Ser Ser Thr Glu Lys His Asp 
                85                  90                  95      


Trp Asp Pro Pro Asp Arg Lys Val Asp Thr Arg Lys Phe Arg Ser Glu 
            100                 105                 110         


Pro Arg Ser Ile Phe Glu Tyr Glu Pro Gly Lys Ser Ser Ile Leu Gln 
        115                 120                 125             


His Glu Arg Pro Ala Ser Leu Tyr Gln Ser Ser Ile Asp Arg Ser Leu 
    130                 135                 140                 


Glu Arg Pro Met Ser Ser Ala Ser Met Ala Ser Asp Phe Arg Lys Arg 
145                 150                 155                 160 


Arg Lys Ser Glu Pro Ala Val Gly Pro Pro Arg Gly Leu Gly Asp Gln 
                165                 170                 175     


Ser Ala Ser Arg Thr Ser Pro Gly Arg Val Asp Leu Pro Gly Ser Ser 
            180                 185                 190         


Thr Thr Leu Thr Lys Ser Phe Thr Ser Ser Ser Pro Ser Ser Pro Ser 
        195                 200                 205             


Arg Ala Lys Gly Gly Asp Asp Ser Lys Ile Cys Pro Ser Leu Cys Ser 
    210                 215                 220                 


Tyr Ser Gly Leu Asn Gly Asn Pro Ser Ser Glu Leu Asp Tyr Cys Ser 
225                 230                 235                 240 


Thr Tyr Arg Gln His Leu Asp Val Pro Arg Asp Ser Pro Arg Ala Ile 
                245                 250                 255     


Ser Phe Lys Asn Gly Trp Gln Met Ala Arg Gln Asn Ala Glu Ile Trp 
            260                 265                 270         


Ser Ser Thr Glu Glu Thr Val Ser Pro Lys Ile Lys Ser Arg Ser Cys 
        275                 280                 285             


Asp Asp Leu Leu Asn Asp Asp Cys Asp Ser Phe Pro Asp Pro Lys Val 
    290                 295                 300                 


Lys Ser Glu Ser Met Gly Ser Leu Leu Cys Glu Glu Asp Ser Lys Glu 
305                 310                 315                 320 


Ser Cys Pro Met Ala Trp Gly Ser Pro Tyr Val Pro Glu Val Arg Ser 
                325                 330                 335     


Asn Gly Arg Ser Arg Ile Arg His Arg Ser Ala Arg Asn Ala Pro Gly 
            340                 345                 350         


Phe Leu Lys Met Tyr Lys Lys Met His Arg Ile Asn Arg Lys Asp Leu 
        355                 360                 365             


Met Asn Ser Glu Val Ile Cys Ser Val Lys Ser Arg Ile Leu Gln Tyr 
    370                 375                 380                 


Glu Ser Glu Gln Gln His Lys Asp Leu Leu Arg Ala Trp Ser Gln Cys 
385                 390                 395                 400 


Ser Thr Glu Glu Val Pro Arg Asp Met Val Pro Thr Arg Ile Ser Glu 
                405                 410                 415     


Phe Glu Lys Leu Ile Gln Lys Ser Lys Ser Met Pro Asn Leu Gly Asp 
            420                 425                 430         


Asp Met Leu Ser Pro Val Thr Leu Glu Pro Pro Gln Asn Gly Leu Cys 
        435                 440                 445             


Pro Lys Arg Arg Phe Ser Ile Glu Tyr Leu Leu Glu Glu Glu Asn Gln 
    450                 455                 460                 


Ser Gly Pro Pro Ala Arg Gly Arg Arg Gly Cys Gln Ser Asn Ala Leu 
465                 470                 475                 480 


Val Pro Ile His Ile Glu Val Thr Ser Asp Glu Gln Pro Arg Ala His 
                485                 490                 495     


Val Glu Phe Ser Asp Ser Asp Gln Asp Gly Val Val Ser Asp His Ser 
            500                 505                 510         


Asp Tyr Ile His Leu Glu Gly Ser Ser Phe Cys Ser Glu Ser Asp Phe 
        515                 520                 525             


Asp His Phe Ser Phe Thr Ser Ser Glu Ser Phe Tyr Gly Ser Ser His 
    530                 535                 540                 


His His His His His His His His His His Arg His Leu Ile Ser Ser 
545                 550                 555                 560 


Cys Lys Gly Arg Cys Pro Ala Ser Tyr Thr Arg Phe Thr Thr Met Leu 
                565                 570                 575     


Lys His Glu Arg Ala Arg His Glu Asn Thr Glu Glu Pro Arg Arg Gln 
            580                 585                 590         


Glu Met Asp Pro Gly Leu Ser Lys Leu Ala Phe Leu Val Ser Pro Val 
        595                 600                 605             


Pro Phe Arg Arg Lys Lys Asn Ser Ala Pro Lys Lys Gln Thr Glu Lys 
    610                 615                 620                 


Ala Lys Cys Lys Ala Ser Val Phe Glu Ala Leu Asp Ser Ala Leu Lys 
625                 630                 635                 640 


Asp Ile Cys Asp Gln Ile Lys Ala Glu Lys Lys Arg Gly Ser Leu Pro 
                645                 650                 655     


Asp Asn Ser Ile Leu His Arg Leu Ile Ser Glu Leu Leu Pro Asp Val 
            660                 665                 670         


Pro Glu Arg Asn Ser Ser Leu Arg Ala Leu Arg Arg Ser Pro Leu His 
        675                 680                 685             


Gln Pro Leu His Pro Leu Pro Pro Asp Gly Ala Ile His Cys Pro Pro 
    690                 695                 700                 


Tyr Gln Asn Asp Cys Gly Arg Met Pro Arg Ser Ala Ser Phe Gln Asp 
705                 710                 715                 720 


Val Asp Thr Ala Asn Ser Ser Cys His His Gln Asp Arg Gly Gly Ala 
                725                 730                 735     


Leu Gln Asp Arg Glu Ser Pro Arg Ser Tyr Ser Ser Thr Leu Thr Asp 
            740                 745                 750         


Met Gly Arg Ser Ala Pro Arg Glu Arg Arg Gly Thr Pro Glu Lys Glu 
        755                 760                 765             


Lys Leu Pro Ala Lys Ala Val Tyr Asp Phe Lys Ala Gln Thr Ser Lys 
    770                 775                 780                 


Glu Leu Ser Phe Lys Lys Gly Asp Thr Val Tyr Ile Leu Arg Lys Ile 
785                 790                 795                 800 


Asp Gln Asn Trp Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe 
                805                 810                 815     


Pro Ile Ser Tyr Val Glu Lys Leu Thr Pro Pro Glu Lys Ala Gln Pro 
            820                 825                 830         


Ala Arg Pro Pro Pro Pro Ala Gln Pro Gly Glu Ile Gly Glu Ala Ile 
        835                 840                 845             


Ala Lys Tyr Asn Phe Asn Ala Asp Thr Asn Val Glu Leu Ser Leu Arg 
    850                 855                 860                 


Lys Gly Asp Arg Val Ile Leu Leu Lys Arg Val Asp Gln Asn Trp Tyr 
865                 870                 875                 880 


Glu Gly Lys Ile Pro Gly Thr Asn Arg Gln Gly Ile Phe Pro Val Ser 
                885                 890                 895     


Tyr Val Glu Val Val Lys Lys Asn Thr Lys Gly Ala Glu Asp Tyr Pro 
            900                 905                 910         


Asp Pro Pro Ile Pro His Ser Tyr Ser Ser Asp Arg Ile His Ser Leu 
        915                 920                 925             


Ser Ser Asn Lys Pro Gln Arg Pro Val Phe Thr His Glu Asn Ile Gln 
    930                 935                 940                 


Gly Gly Gly Glu Pro Phe Gln Ala Leu Tyr Asn Tyr Thr Pro Arg Asn 
945                 950                 955                 960 


Glu Asp Glu Leu Glu Leu Arg Glu Ser Asp Val Ile Asp Val Met Glu 
                965                 970                 975     


Lys Cys Asp Asp Gly Trp Phe Val Gly Thr Ser Arg Arg Thr Lys Phe 
            980                 985                 990         


Phe Gly Thr Phe Pro Gly Asn Tyr  Val Lys Arg Leu 
        995                 1000                 


<210>  3895
<211>  359
<212>  PRT
<213>  homo sapiens

<400>  3895

Met Pro Ser Leu Leu Leu Leu Phe Thr Ala Ala Leu Leu Ser Ser Trp 
1               5                   10                  15      


Ala Gln Leu Leu Thr Asp Ala Asn Ser Trp Trp Ser Leu Ala Leu Asn 
            20                  25                  30          


Pro Val Gln Arg Pro Glu Met Phe Ile Ile Gly Ala Gln Pro Val Cys 
        35                  40                  45              


Ser Gln Leu Pro Gly Leu Ser Pro Gly Gln Arg Lys Leu Cys Gln Leu 
    50                  55                  60                  


Tyr Gln Glu His Met Ala Tyr Ile Gly Glu Gly Ala Lys Thr Gly Ile 
65                  70                  75                  80  


Lys Glu Cys Gln His Gln Phe Arg Gln Arg Arg Trp Asn Cys Ser Thr 
                85                  90                  95      


Ala Asp Asn Ala Ser Val Phe Gly Arg Val Met Gln Ile Gly Ser Arg 
            100                 105                 110         


Glu Thr Ala Phe Thr His Ala Val Ser Ala Ala Gly Val Val Asn Ala 
        115                 120                 125             


Ile Ser Arg Ala Cys Arg Glu Gly Glu Leu Ser Thr Cys Gly Cys Ser 
    130                 135                 140                 


Arg Thr Ala Arg Pro Lys Asp Leu Pro Arg Asp Trp Leu Trp Gly Gly 
145                 150                 155                 160 


Cys Gly Asp Asn Val Glu Tyr Gly Tyr Arg Phe Ala Lys Glu Phe Val 
                165                 170                 175     


Asp Ala Arg Glu Arg Glu Lys Asn Phe Ala Lys Gly Ser Glu Glu Gln 
            180                 185                 190         


Gly Arg Val Leu Met Asn Leu Gln Asn Asn Glu Ala Gly Arg Arg Ala 
        195                 200                 205             


Val Tyr Lys Met Ala Asp Val Ala Cys Lys Cys His Gly Val Ser Gly 
    210                 215                 220                 


Ser Cys Ser Leu Lys Thr Cys Trp Leu Gln Leu Ala Glu Phe Arg Lys 
225                 230                 235                 240 


Val Gly Asp Arg Leu Lys Glu Lys Tyr Asp Ser Ala Ala Ala Met Arg 
                245                 250                 255     


Val Thr Arg Lys Gly Arg Leu Glu Leu Val Asn Ser Arg Phe Thr Gln 
            260                 265                 270         


Pro Thr Pro Glu Asp Leu Val Tyr Val Asp Pro Ser Pro Asp Tyr Cys 
        275                 280                 285             


Leu Arg Asn Glu Ser Thr Gly Ser Leu Gly Thr Gln Gly Arg Leu Cys 
    290                 295                 300                 


Asn Lys Thr Ser Glu Gly Met Asp Gly Cys Glu Leu Met Cys Cys Gly 
305                 310                 315                 320 


Arg Gly Tyr Asn Gln Phe Lys Ser Val Gln Val Glu Arg Cys His Cys 
                325                 330                 335     


Lys Phe His Trp Cys Cys Phe Val Arg Cys Lys Lys Cys Thr Glu Ile 
            340                 345                 350         


Val Asp Gln Tyr Ile Cys Lys 
        355                 


<210>  3896
<211>  1531
<212>  PRT
<213>  homo sapiens

<400>  3896

Met Glu Val Ser Pro Leu Gln Pro Val Asn Glu Asn Met Gln Val Asn 
1               5                   10                  15      


Lys Ile Lys Lys Asn Glu Asp Ala Lys Lys Arg Leu Ser Val Glu Arg 
            20                  25                  30          


Ile Tyr Gln Lys Lys Thr Gln Leu Glu His Ile Leu Leu Arg Pro Asp 
        35                  40                  45              


Thr Tyr Ile Gly Ser Val Glu Leu Val Thr Gln Gln Met Trp Val Tyr 
    50                  55                  60                  


Asp Glu Asp Val Gly Ile Asn Tyr Arg Glu Val Thr Phe Val Pro Gly 
65                  70                  75                  80  


Leu Tyr Lys Ile Phe Asp Glu Ile Leu Val Asn Ala Ala Asp Asn Lys 
                85                  90                  95      


Gln Arg Asp Pro Lys Met Ser Cys Ile Arg Val Thr Ile Asp Pro Glu 
            100                 105                 110         


Asn Asn Leu Ile Ser Ile Trp Asn Asn Gly Lys Gly Ile Pro Val Val 
        115                 120                 125             


Glu His Lys Val Glu Lys Met Tyr Val Pro Ala Leu Ile Phe Gly Gln 
    130                 135                 140                 


Leu Leu Thr Ser Ser Asn Tyr Asp Asp Asp Glu Lys Lys Val Thr Gly 
145                 150                 155                 160 


Gly Arg Asn Gly Tyr Gly Ala Lys Leu Cys Asn Ile Phe Ser Thr Lys 
                165                 170                 175     


Phe Thr Val Glu Thr Ala Ser Arg Glu Tyr Lys Lys Met Phe Lys Gln 
            180                 185                 190         


Thr Trp Met Asp Asn Met Gly Arg Ala Gly Glu Met Glu Leu Lys Pro 
        195                 200                 205             


Phe Asn Gly Glu Asp Tyr Thr Cys Ile Thr Phe Gln Pro Asp Leu Ser 
    210                 215                 220                 


Lys Phe Lys Met Gln Ser Leu Asp Lys Asp Ile Val Ala Leu Met Val 
225                 230                 235                 240 


Arg Arg Ala Tyr Asp Ile Ala Gly Ser Thr Lys Asp Val Lys Val Phe 
                245                 250                 255     


Leu Asn Gly Asn Lys Leu Pro Val Lys Gly Phe Arg Ser Tyr Val Asp 
            260                 265                 270         


Met Tyr Leu Lys Asp Lys Leu Asp Glu Thr Gly Asn Ser Leu Lys Val 
        275                 280                 285             


Ile His Glu Gln Val Asn His Arg Trp Glu Val Cys Leu Thr Met Ser 
    290                 295                 300                 


Glu Lys Gly Phe Gln Gln Ile Ser Phe Val Asn Ser Ile Ala Thr Ser 
305                 310                 315                 320 


Lys Gly Gly Arg His Val Asp Tyr Val Ala Asp Gln Ile Val Thr Lys 
                325                 330                 335     


Leu Val Asp Val Val Lys Lys Lys Asn Lys Gly Gly Val Ala Val Lys 
            340                 345                 350         


Ala His Gln Val Lys Asn His Met Trp Ile Phe Val Asn Ala Leu Ile 
        355                 360                 365             


Glu Asn Pro Thr Phe Asp Ser Gln Thr Lys Glu Asn Met Thr Leu Gln 
    370                 375                 380                 


Pro Lys Ser Phe Gly Ser Thr Cys Gln Leu Ser Glu Lys Phe Ile Lys 
385                 390                 395                 400 


Ala Ala Ile Gly Cys Gly Ile Val Glu Ser Ile Leu Asn Trp Val Lys 
                405                 410                 415     


Phe Lys Ala Gln Val Gln Leu Asn Lys Lys Cys Ser Ala Val Lys His 
            420                 425                 430         


Asn Arg Ile Lys Gly Ile Pro Lys Leu Asp Asp Ala Asn Asp Ala Gly 
        435                 440                 445             


Gly Arg Asn Ser Thr Glu Cys Thr Leu Ile Leu Thr Glu Gly Asp Ser 
    450                 455                 460                 


Ala Lys Thr Leu Ala Val Ser Gly Leu Gly Val Val Gly Arg Asp Lys 
465                 470                 475                 480 


Tyr Gly Val Phe Pro Leu Arg Gly Lys Ile Leu Asn Val Arg Glu Ala 
                485                 490                 495     


Ser His Lys Gln Ile Met Glu Asn Ala Glu Ile Asn Asn Ile Ile Lys 
            500                 505                 510         


Ile Val Gly Leu Gln Tyr Lys Lys Asn Tyr Glu Asp Glu Asp Ser Leu 
        515                 520                 525             


Lys Thr Leu Arg Tyr Gly Lys Ile Met Ile Met Thr Asp Gln Asp Gln 
    530                 535                 540                 


Asp Gly Ser His Ile Lys Gly Leu Leu Ile Asn Phe Ile His His Asn 
545                 550                 555                 560 


Trp Pro Ser Leu Leu Arg His Arg Phe Leu Glu Glu Phe Ile Thr Pro 
                565                 570                 575     


Ile Val Lys Val Ser Lys Asn Lys Gln Glu Met Ala Phe Tyr Ser Leu 
            580                 585                 590         


Pro Glu Phe Glu Glu Trp Lys Ser Ser Thr Pro Asn His Lys Lys Trp 
        595                 600                 605             


Lys Val Lys Tyr Tyr Lys Gly Leu Gly Thr Ser Thr Ser Lys Glu Ala 
    610                 615                 620                 


Lys Glu Tyr Phe Ala Asp Met Lys Arg His Arg Ile Gln Phe Lys Tyr 
625                 630                 635                 640 


Ser Gly Pro Glu Asp Asp Ala Ala Ile Ser Leu Ala Phe Ser Lys Lys 
                645                 650                 655     


Gln Ile Asp Asp Arg Lys Glu Trp Leu Thr Asn Phe Met Glu Asp Arg 
            660                 665                 670         


Arg Gln Arg Lys Leu Leu Gly Leu Pro Glu Asp Tyr Leu Tyr Gly Gln 
        675                 680                 685             


Thr Thr Thr Tyr Leu Thr Tyr Asn Asp Phe Ile Asn Lys Glu Leu Ile 
    690                 695                 700                 


Leu Phe Ser Asn Ser Asp Asn Glu Arg Ser Ile Pro Ser Met Val Asp 
705                 710                 715                 720 


Gly Leu Lys Pro Gly Gln Arg Lys Val Leu Phe Thr Cys Phe Lys Arg 
                725                 730                 735     


Asn Asp Lys Arg Glu Val Lys Val Ala Gln Leu Ala Gly Ser Val Ala 
            740                 745                 750         


Glu Met Ser Ser Tyr His His Gly Glu Met Ser Leu Met Met Thr Ile 
        755                 760                 765             


Ile Asn Leu Ala Gln Asn Phe Val Gly Ser Asn Asn Leu Asn Leu Leu 
    770                 775                 780                 


Gln Pro Ile Gly Gln Phe Gly Thr Arg Leu His Gly Gly Lys Asp Ser 
785                 790                 795                 800 


Ala Ser Pro Arg Tyr Ile Phe Thr Met Leu Ser Ser Leu Ala Arg Leu 
                805                 810                 815     


Leu Phe Pro Pro Lys Asp Asp His Thr Leu Lys Phe Leu Tyr Asp Asp 
            820                 825                 830         


Asn Gln Arg Val Glu Pro Glu Trp Tyr Ile Pro Ile Ile Pro Met Val 
        835                 840                 845             


Leu Ile Asn Gly Ala Glu Gly Ile Gly Thr Gly Trp Ser Cys Lys Ile 
    850                 855                 860                 


Pro Asn Phe Asp Val Arg Glu Ile Val Asn Asn Ile Arg Arg Leu Met 
865                 870                 875                 880 


Asp Gly Glu Glu Pro Leu Pro Met Leu Pro Ser Tyr Lys Asn Phe Lys 
                885                 890                 895     


Gly Thr Ile Glu Glu Leu Ala Pro Asn Gln Tyr Val Ile Ser Gly Glu 
            900                 905                 910         


Val Ala Ile Leu Asn Ser Thr Thr Ile Glu Ile Ser Glu Leu Pro Val 
        915                 920                 925             


Arg Thr Trp Thr Gln Thr Tyr Lys Glu Gln Val Leu Glu Pro Met Leu 
    930                 935                 940                 


Asn Gly Thr Glu Lys Thr Pro Pro Leu Ile Thr Asp Tyr Arg Glu Tyr 
945                 950                 955                 960 


His Thr Asp Thr Thr Val Lys Phe Val Val Lys Met Thr Glu Glu Lys 
                965                 970                 975     


Leu Ala Glu Ala Glu Arg Val Gly Leu His Lys Val Phe Lys Leu Gln 
            980                 985                 990         


Thr Ser Leu Thr Cys Asn Ser Met  Val Leu Phe Asp His  Val Gly Cys 
        995                 1000                 1005             


Leu Lys  Lys Tyr Asp Thr Val  Leu Asp Ile Leu Arg  Asp Phe Phe 
    1010                 1015                 1020             


Glu Leu  Arg Leu Lys Tyr Tyr  Gly Leu Arg Lys Glu  Trp Leu Leu 
    1025                 1030                 1035             


Gly Met  Leu Gly Ala Glu Ser  Ala Lys Leu Asn Asn  Gln Ala Arg 
    1040                 1045                 1050             


Phe Ile  Leu Glu Lys Ile Asp  Gly Lys Ile Ile Ile  Glu Asn Lys 
    1055                 1060                 1065             


Pro Lys  Lys Glu Leu Ile Lys  Val Leu Ile Gln Arg  Gly Tyr Asp 
    1070                 1075                 1080             


Ser Asp  Pro Val Lys Ala Trp  Lys Glu Ala Gln Gln  Lys Val Pro 
    1085                 1090                 1095             


Asp Glu  Glu Glu Asn Glu Glu  Ser Asp Asn Glu Lys  Glu Thr Glu 
    1100                 1105                 1110             


Lys Ser  Asp Ser Val Thr Asp  Ser Gly Pro Thr Phe  Asn Tyr Leu 
    1115                 1120                 1125             


Leu Asp  Met Pro Leu Trp Tyr  Leu Thr Lys Glu Lys  Lys Asp Glu 
    1130                 1135                 1140             


Leu Cys  Arg Leu Arg Asn Glu  Lys Glu Gln Glu Leu  Asp Thr Leu 
    1145                 1150                 1155             


Lys Arg  Lys Ser Pro Ser Asp  Leu Trp Lys Glu Asp  Leu Ala Thr 
    1160                 1165                 1170             


Phe Ile  Glu Glu Leu Glu Ala  Val Glu Ala Lys Glu  Lys Gln Asp 
    1175                 1180                 1185             


Glu Gln  Val Gly Leu Pro Gly  Lys Gly Gly Lys Ala  Lys Gly Lys 
    1190                 1195                 1200             


Lys Thr  Gln Met Ala Glu Val  Leu Pro Ser Pro Arg  Gly Gln Arg 
    1205                 1210                 1215             


Val Ile  Pro Arg Ile Thr Ile  Glu Met Lys Ala Glu  Ala Glu Lys 
    1220                 1225                 1230             


Lys Asn  Lys Lys Lys Ile Lys  Asn Glu Asn Thr Glu  Gly Ser Pro 
    1235                 1240                 1245             


Gln Glu  Asp Gly Val Glu Leu  Glu Gly Leu Lys Gln  Arg Leu Glu 
    1250                 1255                 1260             


Lys Lys  Gln Lys Arg Glu Pro  Gly Thr Lys Thr Lys  Lys Gln Thr 
    1265                 1270                 1275             


Thr Leu  Ala Phe Lys Pro Ile  Lys Lys Gly Lys Lys  Arg Asn Pro 
    1280                 1285                 1290             


Trp Ser  Asp Ser Glu Ser Asp  Arg Ser Ser Asp Glu  Ser Asn Phe 
    1295                 1300                 1305             


Asp Val  Pro Pro Arg Glu Thr  Glu Pro Arg Arg Ala  Ala Thr Lys 
    1310                 1315                 1320             


Thr Lys  Phe Thr Met Asp Leu  Asp Ser Asp Glu Asp  Phe Ser Asp 
    1325                 1330                 1335             


Phe Asp  Glu Lys Thr Asp Asp  Glu Asp Phe Val Pro  Ser Asp Ala 
    1340                 1345                 1350             


Ser Pro  Pro Lys Thr Lys Thr  Ser Pro Lys Leu Ser  Asn Lys Glu 
    1355                 1360                 1365             


Leu Lys  Pro Gln Lys Ser Val  Val Ser Asp Leu Glu  Ala Asp Asp 
    1370                 1375                 1380             


Val Lys  Gly Ser Val Pro Leu  Ser Ser Ser Pro Pro  Ala Thr His 
    1385                 1390                 1395             


Phe Pro  Asp Glu Thr Glu Ile  Thr Asn Pro Val Pro  Lys Lys Asn 
    1400                 1405                 1410             


Val Thr  Val Lys Lys Thr Ala  Ala Lys Ser Gln Ser  Ser Thr Ser 
    1415                 1420                 1425             


Thr Thr  Gly Ala Lys Lys Arg  Ala Ala Pro Lys Gly  Thr Lys Arg 
    1430                 1435                 1440             


Asp Pro  Ala Leu Asn Ser Gly  Val Ser Gln Lys Pro  Asp Pro Ala 
    1445                 1450                 1455             


Lys Thr  Lys Asn Arg Arg Lys  Arg Lys Pro Ser Thr  Ser Asp Asp 
    1460                 1465                 1470             


Ser Asp  Ser Asn Phe Glu Lys  Ile Val Ser Lys Ala  Val Thr Ser 
    1475                 1480                 1485             


Lys Lys  Ser Lys Gly Glu Ser  Asp Asp Phe His Met  Asp Phe Asp 
    1490                 1495                 1500             


Ser Ala  Val Ala Pro Arg Ala  Lys Ser Val Arg Ala  Lys Lys Pro 
    1505                 1510                 1515             


Ile Lys  Tyr Leu Glu Glu Ser  Asp Glu Asp Asp Leu  Phe 
    1520                 1525                 1530     


<210>  3897
<211>  591
<212>  PRT
<213>  homo sapiens

<400>  3897

Met Leu Val Gly Ser Gln Ser Phe Ser Pro Gly Gly Pro Asn Gly Ile 
1               5                   10                  15      


Ile Arg Ser Gln Ser Phe Ala Gly Phe Ser Gly Leu Gln Glu Arg Arg 
            20                  25                  30          


Ser Arg Cys Asn Ser Phe Ile Glu Asn Ser Ser Ala Leu Lys Lys Pro 
        35                  40                  45              


Gln Ala Lys Leu Lys Lys Met His Asn Leu Gly His Lys Asn Asn Asn 
    50                  55                  60                  


Pro Pro Lys Glu Pro Gln Pro Lys Arg Val Glu Glu Val Tyr Arg Ala 
65                  70                  75                  80  


Leu Lys Asn Gly Leu Asp Glu Tyr Leu Glu Val His Gln Thr Glu Leu 
                85                  90                  95      


Asp Lys Leu Thr Ala Gln Leu Lys Asp Met Lys Arg Asn Ser Arg Leu 
            100                 105                 110         


Gly Val Leu Tyr Asp Leu Asp Lys Gln Ile Lys Thr Ile Glu Arg Tyr 
        115                 120                 125             


Met Arg Arg Leu Glu Phe His Ile Ser Lys Val Asp Glu Leu Tyr Glu 
    130                 135                 140                 


Ala Tyr Cys Ile Gln Arg Arg Leu Gln Asp Gly Ala Ser Lys Met Lys 
145                 150                 155                 160 


Gln Ala Phe Ala Thr Ser Pro Ala Ser Lys Ala Ala Arg Glu Ser Leu 
                165                 170                 175     


Thr Glu Ile Asn Arg Ser Phe Lys Glu Tyr Thr Glu Asn Met Cys Thr 
            180                 185                 190         


Ile Glu Val Glu Leu Glu Asn Leu Leu Gly Glu Phe Ser Ile Lys Met 
        195                 200                 205             


Lys Gly Leu Ala Gly Phe Ala Arg Leu Cys Pro Gly Asp Gln Tyr Glu 
    210                 215                 220                 


Ile Phe Met Lys Tyr Gly Arg Gln Arg Trp Lys Leu Lys Gly Lys Ile 
225                 230                 235                 240 


Glu Val Asn Gly Lys Gln Ser Trp Asp Gly Glu Glu Thr Val Phe Leu 
                245                 250                 255     


Pro Leu Ile Val Gly Phe Ile Ser Ile Lys Val Thr Glu Leu Lys Gly 
            260                 265                 270         


Leu Ala Thr His Ile Leu Val Gly Ser Val Thr Cys Glu Thr Lys Glu 
        275                 280                 285             


Leu Phe Ala Ala Arg Pro Gln Val Val Ala Val Asp Ile Asn Asp Leu 
    290                 295                 300                 


Gly Thr Ile Lys Leu Asn Leu Glu Ile Thr Trp Tyr Pro Phe Asp Val 
305                 310                 315                 320 


Glu Asp Met Thr Ala Ser Ser Gly Ala Gly Asn Lys Ala Ala Ala Leu 
                325                 330                 335     


Gln Arg Arg Met Ser Met Tyr Ser Gln Gly Thr Pro Glu Thr Pro Thr 
            340                 345                 350         


Phe Lys Asp His Ser Phe Phe Ser Asn Leu Pro Asp Asp Ile Phe Glu 
        355                 360                 365             


Asn Gly Lys Ala Ala Glu Glu Lys Met Pro Leu Ser Leu Ser Phe Ser 
    370                 375                 380                 


Asp Leu Pro Asn Gly Asp Cys Ala Leu Thr Ser His Ser Thr Gly Ser 
385                 390                 395                 400 


Pro Ser Asn Ser Thr Asn Pro Glu Ile Thr Ile Thr Pro Ala Glu Phe 
                405                 410                 415     


Asn Leu Ser Ser Leu Ala Ser Gln Asn Glu Gly Met Asp Asp Thr Ser 
            420                 425                 430         


Ser Ala Ser Ser Arg Asn Ser Leu Gly Glu Gly Gln Glu Pro Lys Ser 
        435                 440                 445             


His Leu Lys Glu Glu Asp Pro Glu Glu Pro Arg Lys Pro Ala Ser Ala 
    450                 455                 460                 


Pro Ser Glu Ala Cys Arg Arg Gln Ser Ser Gly Ala Gly Ala Glu His 
465                 470                 475                 480 


Leu Phe Leu Glu Asn Asp Val Ala Glu Ala Leu Leu Gln Glu Ser Glu 
                485                 490                 495     


Glu Ala Ser Glu Leu Lys Pro Val Glu Leu Asp Thr Ser Glu Gly Asn 
            500                 505                 510         


Ile Thr Lys Gln Leu Val Lys Arg Leu Thr Ser Ala Glu Val Pro Met 
        515                 520                 525             


Ala Thr Asp Arg Leu Leu Ser Glu Gly Ser Val Gly Gly Glu Ser Glu 
    530                 535                 540                 


Gly Cys Arg Ser Phe Leu Asp Gly Ser Leu Glu Asp Ala Phe Asn Gly 
545                 550                 555                 560 


Leu Leu Leu Ala Leu Glu Pro His Lys Glu Gln Tyr Lys Glu Phe Gln 
                565                 570                 575     


Asp Leu Asn Gln Glu Val Met Asn Leu Asp Asp Ile Leu Lys Lys 
            580                 585                 590     


<210>  3898
<211>  429
<212>  PRT
<213>  homo sapiens

<400>  3898

Met Gly Arg Lys Lys Ile Gln Ile Thr Arg Ile Met Asp Glu Arg Asn 
1               5                   10                  15      


Arg Gln Thr Leu Arg Lys Lys Gly Leu Asn Gly Cys Glu Ser Pro Asp 
            20                  25                  30          


Ala Asp Asp Tyr Phe Glu His Ser Pro Leu Ser Glu Asp Arg Phe Ser 
        35                  40                  45              


Lys Leu Asn Glu Asp Ser Asp Phe Ile Phe Lys Arg Gly Pro Pro Gly 
    50                  55                  60                  


Leu Pro Pro Gln Asn Phe Ser Met Ser Val Thr Val Pro Val Thr Ser 
65                  70                  75                  80  


Pro Asn Ala Leu Ser Tyr Thr Asn Pro Gly Ser Ser Leu Val Ser Pro 
                85                  90                  95      


Ser Leu Ala Ala Ser Ser Thr Leu Thr Asp Ser Ser Met Leu Ser Pro 
            100                 105                 110         


Pro Gln Thr Thr Leu His Arg Asn Val Ser Pro Gly Ala Pro Gln Arg 
        115                 120                 125             


Pro Pro Ser Thr Gly Asn Ala Gly Gly Met Leu Ser Thr Thr Asp Leu 
    130                 135                 140                 


Thr Val Pro Asn Gly Ala Gly Ser Ser Pro Val Gly Asn Gly Phe Val 
145                 150                 155                 160 


Asn Ser Arg Ala Ser Pro Asn Leu Ile Gly Ala Thr Gly Ala Asn Ser 
                165                 170                 175     


Leu Gly Lys Val Met Pro Thr Lys Ser Pro Pro Pro Pro Gly Gly Gly 
            180                 185                 190         


Asn Leu Gly Met Asn Ser Arg Lys Pro Asp Leu Arg Val Val Ile Pro 
        195                 200                 205             


Pro Ser Ser Lys Gly Met Met Pro Pro Leu Asn Thr Gln Arg Ile Ser 
    210                 215                 220                 


Ser Ser Gln Ala Thr Gln Pro Leu Ala Thr Pro Val Val Ser Val Thr 
225                 230                 235                 240 


Thr Pro Ser Leu Pro Pro Gln Gly Leu Val Tyr Ser Ala Met Pro Thr 
                245                 250                 255     


Ala Tyr Asn Thr Asp Tyr Ser Leu Thr Ser Ala Asp Leu Ser Ala Leu 
            260                 265                 270         


Gln Gly Phe Asn Ser Pro Gly Met Leu Ser Leu Gly Gln Val Ser Ala 
        275                 280                 285             


Trp Gln Gln His His Leu Gly Gln Ala Ala Leu Ser Ser Leu Val Ala 
    290                 295                 300                 


Gly Gly Gln Leu Ser Gln Gly Ser Asn Leu Ser Ile Asn Thr Asn Gln 
305                 310                 315                 320 


Asn Ile Ser Ile Lys Ser Glu Pro Ile Ser Pro Pro Arg Asp Arg Met 
                325                 330                 335     


Thr Pro Ser Gly Phe Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln 
            340                 345                 350         


Pro Pro Pro Pro Pro Gln Pro Gln Pro Gln Pro Pro Gln Pro Gln Pro 
        355                 360                 365             


Arg Gln Glu Met Gly Arg Ser Pro Val Asp Ser Leu Ser Ser Ser Ser 
    370                 375                 380                 


Ser Ser Tyr Asp Gly Ser Asp Arg Glu Asp Pro Arg Gly Asp Phe His 
385                 390                 395                 400 


Ser Pro Ile Val Leu Gly Arg Pro Pro Asn Thr Glu Asp Arg Glu Ser 
                405                 410                 415     


Pro Ser Val Lys Arg Met Arg Met Asp Ala Trp Val Thr 
            420                 425                 


<210>  3899
<211>  4022
<212>  PRT
<213>  homo sapiens

<400>  3899

Met Leu Glu Ser Tyr Val Thr Pro Ile Leu Met Ser Tyr Val Asn Arg 
1               5                   10                  15      


Tyr Ile Lys Asn Leu Lys Pro Ser Asp Leu Gln Leu Ser Leu Trp Gly 
            20                  25                  30          


Gly Asp Val Val Leu Ser Lys Leu Glu Leu Lys Leu Asp Val Leu Glu 
        35                  40                  45              


Gln Glu Leu Lys Leu Pro Phe Thr Phe Leu Ser Gly His Ile His Glu 
    50                  55                  60                  


Leu Arg Ile His Val Pro Trp Thr Lys Leu Gly Ser Glu Pro Val Val 
65                  70                  75                  80  


Ile Thr Ile Asn Thr Met Glu Cys Ile Leu Lys Leu Lys Asp Gly Ile 
                85                  90                  95      


Gln Asp Asp His Glu Ser Cys Gly Ser Asn Ser Thr Asn Arg Ser Thr 
            100                 105                 110         


Ala Glu Ser Thr Lys Ser Ser Ile Lys Pro Arg Arg Met Gln Gln Ala 
        115                 120                 125             


Ala Pro Thr Asp Pro Asp Leu Pro Pro Gly Tyr Val Gln Ser Leu Ile 
    130                 135                 140                 


Arg Arg Val Val Asn Asn Val Asn Ile Val Ile Asn Asn Leu Ile Leu 
145                 150                 155                 160 


Lys Tyr Val Glu Asp Asp Ile Val Leu Ser Val Asn Ile Thr Ser Ala 
                165                 170                 175     


Glu Cys Tyr Thr Val Gly Glu Leu Trp Asp Arg Ala Phe Met Asp Ile 
            180                 185                 190         


Ser Ala Thr Asp Leu Val Leu Arg Lys Val Ile Asn Phe Ser Asp Cys 
        195                 200                 205             


Thr Val Cys Leu Asp Lys Arg Asn Ala Ser Gly Lys Ile Glu Phe Tyr 
    210                 215                 220                 


Gln Asp Pro Leu Leu Tyr Lys Cys Ser Phe Arg Thr Arg Leu His Phe 
225                 230                 235                 240 


Thr Tyr Glu Asn Leu Asn Ser Lys Met Pro Ser Val Ile Lys Ile His 
                245                 250                 255     


Thr Leu Val Glu Ser Leu Lys Leu Ser Ile Thr Asp Gln Gln Leu Pro 
            260                 265                 270         


Met Phe Ile Arg Ile Met Gln Leu Gly Ile Ala Leu Tyr Tyr Gly Glu 
        275                 280                 285             


Ile Gly Asn Phe Lys Glu Gly Glu Ile Glu Asp Leu Thr Cys His Asn 
    290                 295                 300                 


Lys Asp Met Leu Gly Asn Ile Thr Gly Ser Glu Asp Glu Thr Arg Ile 
305                 310                 315                 320 


Asp Met Gln Tyr Pro Ala Gln His Lys Gly Gln Glu Leu Tyr Ser Gln 
                325                 330                 335     


Gln Asp Glu Glu Gln Pro Gln Gly Trp Val Ser Trp Ala Trp Ser Phe 
            340                 345                 350         


Val Pro Ala Ile Val Ser Tyr Asp Asp Gly Glu Glu Asp Phe Val Gly 
        355                 360                 365             


Asn Asp Pro Ala Ser Thr Met His Gln Gln Lys Ala Gln Thr Leu Lys 
    370                 375                 380                 


Asp Pro Ile Val Ser Ile Gly Phe Tyr Cys Thr Lys Ala Thr Val Thr 
385                 390                 395                 400 


Phe Lys Leu Thr Glu Met Gln Val Glu Ser Ser Tyr Tyr Ser Pro Gln 
                405                 410                 415     


Lys Val Lys Ser Lys Glu Val Leu Cys Trp Glu Gln Glu Gly Thr Thr 
            420                 425                 430         


Val Glu Ala Leu Met Met Gly Glu Pro Phe Phe Asp Cys Gln Ile Gly 
        435                 440                 445             


Phe Val Gly Cys Arg Ala Met Cys Leu Lys Gly Ile Met Gly Val Lys 
    450                 455                 460                 


Asp Phe Glu Glu Asn Met Asn Arg Ser Glu Thr Glu Ala Cys Phe Phe 
465                 470                 475                 480 


Ile Cys Gly Asp Asn Leu Ser Thr Lys Gly Phe Thr Tyr Leu Thr Asn 
                485                 490                 495     


Ser Leu Phe Asp Tyr Arg Ser Pro Glu Asn Asn Gly Thr Arg Ala Glu 
            500                 505                 510         


Phe Ile Leu Asp Ser Thr His His Lys Glu Thr Tyr Thr Glu Ile Ala 
        515                 520                 525             


Gly Met Gln Arg Phe Gly Ala Phe Tyr Met Asp Tyr Leu Tyr Thr Met 
    530                 535                 540                 


Glu Asn Thr Ser Gly Lys Gly Ser Thr Asn Gln Gln Asp Phe Ser Ser 
545                 550                 555                 560 


Gly Lys Ser Glu Asp Leu Gly Thr Val Gln Glu Lys Ser Thr Lys Ser 
                565                 570                 575     


Leu Val Ile Gly Pro Leu Asp Phe Arg Leu Asp Ser Ser Ala Val His 
            580                 585                 590         


Arg Ile Leu Lys Met Ile Val Cys Ala Leu Glu His Glu Tyr Glu Pro 
        595                 600                 605             


Tyr Ser Arg Leu Lys Ser Asp Ile Lys Asp Glu Asn Glu Thr Ile Leu 
    610                 615                 620                 


Asn Pro Glu Glu Val Ala Leu Leu Glu Glu Tyr Ile Pro Thr Arg His 
625                 630                 635                 640 


Thr Ser Val Thr Leu Leu Lys Cys Thr Cys Thr Ile Ser Met Ala Glu 
                645                 650                 655     


Phe Asn Leu Leu Asp His Leu Leu Pro Val Ile Met Gly Glu Lys Asn 
            660                 665                 670         


Ser Ser Asn Phe Met Asn Thr Thr Asn Phe Gln Ser Leu Arg Pro Leu 
        675                 680                 685             


Pro Ser Ile Arg Ile Leu Val Asp Lys Ile Asn Leu Glu His Ser Val 
    690                 695                 700                 


Pro Met Tyr Ala Glu Gln Leu Val His Val Val Ser Ser Leu Thr Gln 
705                 710                 715                 720 


Pro Ser Asp Asn Leu Leu His Tyr Cys Tyr Val His Cys Tyr Leu Lys 
                725                 730                 735     


Ile Phe Gly Phe Gln Ala Gly Leu Thr Ser Leu Asp Cys Ser Gly Ser 
            740                 745                 750         


Tyr Cys Leu Pro Val Pro Val Ile Pro Ser Phe Ser Thr Ala Leu Tyr 
        755                 760                 765             


Gly Lys Leu Leu Lys Leu Pro Thr Cys Trp Thr Lys Arg Ser Gln Ile 
    770                 775                 780                 


Ala Ile Thr Glu Gly Ile Phe Glu Leu Pro Asn Leu Thr Ile Gln Ala 
785                 790                 795                 800 


Thr Arg Ala Gln Thr Leu Leu Leu Gln Ala Ile Tyr Gln Ser Trp Ser 
                805                 810                 815     


His Leu Gly Asn Val Ser Ser Ser Ala Val Ile Glu Ala Leu Ile Asn 
            820                 825                 830         


Glu Ile Phe Leu Ser Ile Gly Val Lys Ser Lys Asn Pro Leu Pro Thr 
        835                 840                 845             


Leu Glu Gly Ser Ile Gln Asn Val Glu Leu Lys Tyr Cys Ser Thr Ser 
    850                 855                 860                 


Leu Val Lys Cys Ala Ser Gly Thr Met Gly Ser Ile Lys Ile Cys Ala 
865                 870                 875                 880 


Lys Ala Pro Val Asp Ser Gly Lys Glu Lys Leu Ile Pro Leu Leu Gln 
                885                 890                 895     


Gly Pro Ser Asp Thr Lys Asp Leu His Ser Thr Lys Trp Leu Asn Glu 
            900                 905                 910         


Ser Arg Lys Pro Glu Ser Leu Leu Ala Pro Asp Leu Met Ala Phe Thr 
        915                 920                 925             


Ile Gln Val Pro Gln Tyr Ile Asp Tyr Cys His Asn Ser Gly Ala Val 
    930                 935                 940                 


Leu Leu Cys Ser Ile Gln Gly Leu Ala Val Asn Ile Asp Pro Ile Leu 
945                 950                 955                 960 


Tyr Thr Trp Leu Ile Tyr Gln Pro Gln Lys Arg Thr Ser Arg His Met 
                965                 970                 975     


Gln Gln Gln Pro Val Val Ala Val Pro Leu Val Met Pro Val Cys Arg 
            980                 985                 990         


Arg Lys Glu Asp Glu Val Ser Ile  Gly Ser Ala Pro Leu  Ala Lys Gln 
        995                 1000                 1005             


Gln Ser  Tyr Gln Ala Ser Glu  Tyr Ala Ser Ser Pro  Val Lys Thr 
    1010                 1015                 1020             


Lys Thr  Val Thr Glu Ser Arg  Pro Leu Ser Val Pro  Val Lys Ala 
    1025                 1030                 1035             


Met Leu  Asn Ile Ser Glu Ser  Cys Arg Ser Pro Glu  Glu Arg Met 
    1040                 1045                 1050             


Lys Glu  Phe Ile Gly Ile Val  Trp Asn Ala Val Lys  His Leu Thr 
    1055                 1060                 1065             


Leu Gln  Leu Glu Val Gln Ser  Cys Cys Val Phe Ile  Pro Asn Asp 
    1070                 1075                 1080             


Ser Leu  Pro Ser Pro Ser Thr  Ile Val Ser Gly Asp  Ile Pro Gly 
    1085                 1090                 1095             


Thr Val  Arg Ser Trp Tyr His  Gly Gln Thr Ser Met  Pro Gly Thr 
    1100                 1105                 1110             


Leu Val  Leu Cys Leu Pro Gln  Ile Lys Ile Ile Ser  Ala Gly His 
    1115                 1120                 1125             


Lys Tyr  Met Glu Pro Leu Gln  Glu Ile Pro Phe Val  Ile Pro Arg 
    1130                 1135                 1140             


Pro Ile  Leu Glu Glu Gly Asp  Ala Phe Pro Trp Thr  Ile Ser Leu 
    1145                 1150                 1155             


His Asn  Phe Ser Ile Tyr Thr  Leu Leu Gly Lys Gln  Val Thr Leu 
    1160                 1165                 1170             


Cys Leu  Val Glu Pro Met Gly  Cys Thr Ser Thr Leu  Ala Val Thr 
    1175                 1180                 1185             


Ser Gln  Lys Leu Leu Ala Thr  Gly Pro Asp Thr Arg  His Ser Phe 
    1190                 1195                 1200             


Val Val  Cys Leu His Val Asp  Leu Glu Ser Leu Glu  Ile Lys Cys 
    1205                 1210                 1215             


Ser Asn  Pro Gln Val Gln Leu  Phe Tyr Glu Leu Thr  Asp Ile Met 
    1220                 1225                 1230             


Asn Lys  Val Trp Asn Lys Ile  Gln Lys Arg Gly Asn  Leu Asn Leu 
    1235                 1240                 1245             


Ser Pro  Thr Ser Pro Glu Thr  Met Ala Gly Pro Val  Pro Thr Ser 
    1250                 1255                 1260             


Pro Val  Arg Ser Ser Ile Gly  Thr Ala Pro Pro Asp  Thr Ser Thr 
    1265                 1270                 1275             


Cys Ser  Pro Ser Ala Asp Ile  Gly Thr Thr Thr Glu  Gly Asp Ser 
    1280                 1285                 1290             


Ile Gln  Ala Gly Glu Glu Ser  Pro Phe Ser Asp Ser  Val Thr Leu 
    1295                 1300                 1305             


Glu Gln  Thr Thr Ser Asn Ile  Gly Gly Thr Ser Gly  Arg Val Ser 
    1310                 1315                 1320             


Leu Trp  Met Gln Trp Val Leu  Pro Lys Ile Thr Ile  Lys Leu Phe 
    1325                 1330                 1335             


Ala Pro  Asp Pro Glu Asn Lys  Gly Thr Glu Val Cys  Met Val Ser 
    1340                 1345                 1350             


Glu Leu  Glu Asp Leu Ser Ala  Ser Ile Asp Val Gln  Asp Val Tyr 
    1355                 1360                 1365             


Thr Lys  Val Lys Cys Lys Ile  Glu Ser Phe Asn Ile  Asp His Tyr 
    1370                 1375                 1380             


Arg Ser  Ser Leu Gly Glu Glu  Cys Trp Ser Leu Gly  Gln Cys Gly 
    1385                 1390                 1395             


Gly Val  Phe Leu Ser Cys Thr  Asp Lys Leu Asn Arg  Arg Thr Leu 
    1400                 1405                 1410             


Leu Val  Arg Pro Ile Ser Lys  Gln Asp Pro Phe Ser  Asn Cys Ser 
    1415                 1420                 1425             


Gly Phe  Phe Pro Ser Thr Thr  Thr Lys Leu Leu Asp  Gly Thr His 
    1430                 1435                 1440             


Gln Gln  His Gly Phe Leu Ser  Leu Thr Tyr Thr Lys  Ala Val Thr 
    1445                 1450                 1455             


Lys Asn  Val Arg His Lys Leu  Thr Ser Arg Asn Glu  Arg Arg Ser 
    1460                 1465                 1470             


Phe His  Lys Leu Ser Glu Gly  Leu Met Asp Gly Ser  Pro His Phe 
    1475                 1480                 1485             


Leu His  Glu Ile Leu Leu Ser  Ala Gln Ala Phe Asp  Ile Val Leu 
    1490                 1495                 1500             


Tyr Phe  Pro Leu Leu Asn Ala  Ile Ala Ser Ile Phe  Gln Ala Lys 
    1505                 1510                 1515             


Leu Pro  Lys Thr Gln Lys Glu  Lys Arg Lys Ser Pro  Gly Gln Pro 
    1520                 1525                 1530             


Met Arg  Thr His Thr Leu Thr  Ser Arg Asn Leu Pro  Leu Ile Tyr 
    1535                 1540                 1545             


Val Asn  Thr Ser Val Ile Arg  Ile Phe Ile Pro Lys  Thr Glu Glu 
    1550                 1555                 1560             


Met Gln  Pro Thr Val Glu Ala  Asn Gln Ala Ala Lys  Glu Asp Thr 
    1565                 1570                 1575             


Val Val  Leu Lys Ile Gly Ser  Val Ala Met Ala Pro  Gln Ala Asp 
    1580                 1585                 1590             


Asn Pro  Leu Gly Arg Ser Val  Leu Arg Lys Asp Ile  Tyr Gln Arg 
    1595                 1600                 1605             


Ala Leu  Asn Leu Gly Ile Leu  Arg Asp Pro Gly Ser  Glu Ile Glu 
    1610                 1615                 1620             


Asp Arg  Gln Tyr Gln Ile Asp  Leu Gln Ser Ile Asn  Ile Gly Thr 
    1625                 1630                 1635             


Ala Gln  Trp His Gln Leu Lys  Pro Glu Lys Glu Ser  Val Ser Gly 
    1640                 1645                 1650             


Gly Val  Val Thr Glu Thr Glu  Arg Asn Ser Gln Asn  Pro Ala Leu 
    1655                 1660                 1665             


Glu Trp  Asn Met Ala Ser Ser  Ile Arg Arg His Gln  Glu Arg Arg 
    1670                 1675                 1680             


Ala Ile  Leu Thr Pro Val Leu  Thr Asp Phe Ser Val  Arg Ile Thr 
    1685                 1690                 1695             


Gly Ala  Pro Ala Val Ile Phe  Thr Lys Val Val Ser  Pro Glu Asn 
    1700                 1705                 1710             


Leu His  Thr Glu Glu Ile Leu  Val Cys Gly His Ser  Leu Glu Val 
    1715                 1720                 1725             


Asn Ile  Thr Thr Asn Leu Asp  Phe Phe Leu Ser Val  Ala Gln Val 
    1730                 1735                 1740             


Gln Leu  Leu His Gln Leu Ile  Val Ala Asn Met Thr  Gly Leu Glu 
    1745                 1750                 1755             


Pro Ser  Asn Lys Ala Ala Glu  Ile Ser Lys Gln Glu  Gln Lys Lys 
    1760                 1765                 1770             


Val Asp  Ile Phe Asp Gly Gly  Met Ala Glu Thr Ser  Ser Arg Tyr 
    1775                 1780                 1785             


Ser Gly  Ala Gln Asp Ser Gly  Ile Gly Ser Asp Ser  Val Lys Ile 
    1790                 1795                 1800             


Arg Ile  Val Gln Ile Glu Gln  His Ser Gly Ala Ser  Gln His Arg 
    1805                 1810                 1815             


Ile Ala  Arg Pro Ser Arg Gln  Ser Ser Ile Val Lys  Asn Leu Asn 
    1820                 1825                 1830             


Phe Ile  Pro Phe Asp Ile Phe  Ile Thr Ala Ser Arg  Ile Ser Leu 
    1835                 1840                 1845             


Met Thr  Tyr Ser Cys Met Ala  Leu Ser Lys Ser Lys  Ser Gln Glu 
    1850                 1855                 1860             


Gln Lys  Asn Asn Glu Lys Thr  Asp Lys Ser Ser Leu  Asn Leu Pro 
    1865                 1870                 1875             


Glu Val  Asp Ser Asp Val Ala  Lys Pro Asn Gln Ala  Cys Ile Ser 
    1880                 1885                 1890             


Thr Val  Thr Ala Glu Asp Leu  Leu Arg Ser Ser Ile  Ser Phe Pro 
    1895                 1900                 1905             


Ser Gly  Lys Lys Ile Gly Val  Leu Ser Leu Glu Ser  Leu His Ala 
    1910                 1915                 1920             


Ser Thr  Arg Ser Ser Ala Arg  Gln Ala Leu Gly Ile  Thr Ile Val 
    1925                 1930                 1935             


Arg Gln  Pro Gly Arg Arg Gly  Thr Gly Asp Leu Gln  Leu Glu Pro 
    1940                 1945                 1950             


Phe Leu  Tyr Phe Ile Val Ser  Gln Pro Ser Leu Leu  Leu Ser Cys 
    1955                 1960                 1965             


His His  Arg Lys Gln Arg Val  Glu Val Ser Ile Phe  Asp Ala Val 
    1970                 1975                 1980             


Leu Lys  Gly Val Ala Ser Asp  Tyr Lys Cys Ile Asp  Pro Gly Lys 
    1985                 1990                 1995             


Thr Leu  Pro Glu Ala Leu Asp  Tyr Cys Thr Val Trp  Leu Gln Thr 
    2000                 2005                 2010             


Val Pro  Gly Glu Ile Asp Ser  Lys Ser Gly Ile Pro  Pro Ser Phe 
    2015                 2020                 2025             


Ile Thr  Leu Gln Ile Lys Asp  Phe Leu Asn Gly Pro  Ala Asp Val 
    2030                 2035                 2040             


Asn Leu  Asp Ile Ser Lys Pro  Leu Lys Ala Asn Leu  Ser Phe Thr 
    2045                 2050                 2055             


Lys Leu  Asp Gln Ile Asn Leu  Phe Leu Lys Lys Ile  Lys Asn Ala 
    2060                 2065                 2070             


His Ser  Leu Ala His Ser Glu  Glu Thr Ser Ala Met  Ser Asn Thr 
    2075                 2080                 2085             


Met Val  Asn Lys Asp Asp Leu  Pro Val Ser Lys Tyr  Tyr Arg Gly 
    2090                 2095                 2100             


Lys Leu  Ser Lys Pro Lys Ile  His Gly Asp Gly Val  Gln Lys Ile 
    2105                 2110                 2115             


Ser Ala  Gln Glu Asn Met Trp  Arg Ala Val Ser Cys  Phe Gln Lys 
    2120                 2125                 2130             


Ile Ser  Val Gln Thr Thr Gln  Ile Val Ile Ser Met  Glu Thr Val 
    2135                 2140                 2145             


Pro His  Thr Ser Lys Pro Cys  Leu Leu Ala Ser Leu  Ser Asn Leu 
    2150                 2155                 2160             


Asn Gly  Ser Leu Ser Val Lys  Ala Thr Gln Lys Val  Pro Gly Ile 
    2165                 2170                 2175             


Ile Leu  Gly Ser Ser Phe Leu  Leu Ser Ile Asn Asp  Phe Leu Leu 
    2180                 2185                 2190             


Lys Thr  Ser Leu Lys Glu Arg  Ser Arg Ile Leu Ile  Gly Pro Cys 
    2195                 2200                 2205             


Cys Ala  Thr Ala Asn Leu Glu  Ala Lys Trp Cys Lys  His Ser Gly 
    2210                 2215                 2220             


Asn Pro  Gly Pro Glu Gln Ser  Ile Pro Lys Ile Ser  Ile Asp Leu 
    2225                 2230                 2235             


Arg Gly  Gly Leu Leu Gln Val  Phe Trp Gly Gln Glu  His Leu Asn 
    2240                 2245                 2250             


Cys Leu  Val Leu Leu His Glu  Leu Leu Asn Gly Tyr  Leu Asn Glu 
    2255                 2260                 2265             


Glu Gly  Asn Phe Glu Val Gln  Val Ser Glu Pro Val  Pro Gln Met 
    2270                 2275                 2280             


Ser Ser  Pro Val Glu Lys Asn  Gln Thr Phe Lys Ser  Glu Gln Ser 
    2285                 2290                 2295             


Ser Asp  Asp Leu Arg Thr Gly  Leu Phe Gln Tyr Val  Gln Asp Ala 
    2300                 2305                 2310             


Glu Ser  Leu Lys Leu Pro Gly  Val Tyr Glu Val Leu  Phe Tyr Asn 
    2315                 2320                 2325             


Glu Thr  Glu Asp Cys Pro Gly  Met Met Leu Trp Arg  Tyr Pro Glu 
    2330                 2335                 2340             


Pro Arg  Val Leu Thr Leu Val  Arg Ile Thr Pro Val  Pro Phe Asn 
    2345                 2350                 2355             


Thr Thr  Glu Asp Pro Asp Ile  Ser Thr Ala Asp Leu  Gly Asp Val 
    2360                 2365                 2370             


Leu Gln  Val Pro Cys Ser Leu  Glu Tyr Trp Asp Glu  Leu Gln Lys 
    2375                 2380                 2385             


Val Phe  Val Ala Phe Arg Glu  Phe Asn Leu Ser Glu  Ser Lys Val 
    2390                 2395                 2400             


Cys Glu  Leu Gln Leu Pro Asp  Ile Asn Leu Val Asn  Asp Gln Lys 
    2405                 2410                 2415             


Lys Leu  Val Ser Ser Asp Leu  Trp Arg Ile Val Leu  Asn Ser Ser 
    2420                 2425                 2430             


Gln Asn  Gly Ala Asp Asp Gln  Ser Ser Ala Ser Glu  Ser Gly Ser 
    2435                 2440                 2445             


Gln Ser  Thr Cys Asp Pro Leu  Val Thr Pro Thr Ala  Leu Ala Ala 
    2450                 2455                 2460             


Cys Thr  Arg Val Asp Ser Cys  Phe Thr Pro Trp Phe  Val Pro Ser 
    2465                 2470                 2475             


Leu Cys  Val Ser Phe Gln Phe  Ala His Leu Glu Phe  His Leu Cys 
    2480                 2485                 2490             


His His  Leu Asp Gln Leu Gly  Thr Ala Ala Pro Gln  Tyr Leu Gln 
    2495                 2500                 2505             


Pro Phe  Val Ser Asp Arg Asn  Met Pro Ser Glu Leu  Glu Tyr Met 
    2510                 2515                 2520             


Ile Val  Ser Phe Arg Glu Pro  His Met Tyr Leu Arg  Gln Trp Asn 
    2525                 2530                 2535             


Asn Gly  Ser Val Cys Gln Glu  Ile Gln Phe Leu Ala  Gln Ala Asp 
    2540                 2545                 2550             


Cys Lys  Leu Leu Glu Cys Arg  Asn Val Thr Met Gln  Ser Val Val 
    2555                 2560                 2565             


Lys Pro  Phe Ser Ile Phe Gly  Gln Met Ala Val Ser  Ser Asp Val 
    2570                 2575                 2580             


Val Glu  Lys Leu Leu Asp Cys  Thr Val Ile Val Asp  Ser Val Phe 
    2585                 2590                 2595             


Val Asn  Leu Gly Gln His Val  Val His Ser Leu Asn  Thr Ala Ile 
    2600                 2605                 2610             


Gln Ala  Trp Gln Gln Asn Lys  Cys Pro Glu Val Glu  Glu Leu Val 
    2615                 2620                 2625             


Phe Ser  His Phe Val Ile Cys  Asn Asp Thr Gln Glu  Thr Leu Arg 
    2630                 2635                 2640             


Phe Gly  Gln Val Asp Thr Asp  Glu Asn Ile Leu Leu  Ala Ser Leu 
    2645                 2650                 2655             


His Ser  His Gln Tyr Ser Trp  Arg Ser His Lys Ser  Pro Gln Leu 
    2660                 2665                 2670             


Leu His  Ile Cys Ile Glu Gly  Trp Gly Asn Trp Arg  Trp Ser Glu 
    2675                 2680                 2685             


Pro Phe  Ser Val Asp His Ala  Gly Thr Phe Ile Arg  Thr Ile Gln 
    2690                 2695                 2700             


Tyr Arg  Gly Arg Thr Ala Ser  Leu Ile Ile Lys Val  Gln Gln Leu 
    2705                 2710                 2715             


Asn Gly  Val Gln Lys Gln Ile  Ile Ile Cys Gly Arg  Gln Ile Ile 
    2720                 2725                 2730             


Cys Ser  Tyr Leu Ser Gln Ser  Ile Glu Leu Lys Val  Val Gln His 
    2735                 2740                 2745             


Tyr Ile  Gly Gln Asp Gly Gln  Ala Val Val Arg Glu  His Phe Asp 
    2750                 2755                 2760             


Cys Leu  Thr Ala Lys Gln Lys  Leu Pro Ser Tyr Ile  Leu Glu Asn 
    2765                 2770                 2775             


Asn Glu  Leu Thr Glu Leu Cys  Val Lys Ala Lys Gly  Asp Glu Asp 
    2780                 2785                 2790             


Trp Ser  Arg Asp Val Cys Leu  Glu Ser Lys Ala Pro  Glu Tyr Ser 
    2795                 2800                 2805             


Ile Val  Ile Gln Val Pro Ser  Ser Asn Ser Ser Ile  Ile Tyr Val 
    2810                 2815                 2820             


Trp Cys  Thr Val Leu Thr Leu  Glu Pro Asn Ser Gln  Val Gln Gln 
    2825                 2830                 2835             


Arg Met  Ile Val Phe Ser Pro  Leu Phe Ile Met Arg  Ser His Leu 
    2840                 2845                 2850             


Pro Asp  Pro Ile Ile Ile His  Leu Glu Lys Arg Ser  Leu Gly Leu 
    2855                 2860                 2865             


Ser Glu  Thr Gln Ile Ile Pro  Gly Lys Gly Gln Glu  Lys Pro Leu 
    2870                 2875                 2880             


Gln Asn  Ile Glu Pro Asp Leu  Val His His Leu Thr  Phe Gln Ala 
    2885                 2890                 2895             


Arg Glu  Glu Tyr Asp Pro Ser  Asp Cys Ala Val Pro  Ile Ser Thr 
    2900                 2905                 2910             


Ser Leu  Ile Lys Gln Ile Ala  Thr Lys Val His Pro  Gly Gly Thr 
    2915                 2920                 2925             


Val Asn  Gln Ile Leu Asp Glu  Phe Tyr Gly Pro Glu  Lys Ser Leu 
    2930                 2935                 2940             


Gln Pro  Ile Trp Pro Tyr Asn  Lys Lys Asp Ser Asp  Arg Asn Glu 
    2945                 2950                 2955             


Gln Leu  Ser Gln Trp Asp Ser  Pro Met Arg Val Lys  Leu Ser Ile 
    2960                 2965                 2970             


Trp Lys  Pro Tyr Val Arg Thr  Leu Leu Ile Glu Leu  Leu Pro Trp 
    2975                 2980                 2985             


Ala Leu  Leu Ile Asn Glu Ser  Lys Trp Asp Leu Trp  Leu Phe Glu 
    2990                 2995                 3000             


Gly Glu  Lys Ile Val Leu Gln  Val Pro Ala Gly Lys  Ile Ile Ile 
    3005                 3010                 3015             


Pro Pro  Asn Phe Gln Glu Ala  Phe Gln Ile Gly Ile  Tyr Trp Ala 
    3020                 3025                 3030             


Asn Thr  Asn Thr Val His Lys  Ser Val Ala Ile Lys  Leu Val His 
    3035                 3040                 3045             


Asn Leu  Thr Ser Pro Lys Trp  Lys Asp Gly Gly Asn  Gly Glu Val 
    3050                 3055                 3060             


Val Thr  Leu Asp Glu Glu Ala  Phe Val Asp Thr Glu  Ile Arg Leu 
    3065                 3070                 3075             


Gly Ala  Phe Pro Gly His Gln  Lys Leu Cys Gln Phe  Cys Ile Ser 
    3080                 3085                 3090             


Ser Met  Val Gln Gln Gly Ile  Gln Ile Ile Gln Ile  Glu Asp Lys 
    3095                 3100                 3105             


Thr Thr  Ile Ile Asn Asn Thr  Pro Tyr Gln Ile Phe  Tyr Lys Pro 
    3110                 3115                 3120             


Gln Leu  Ser Val Cys Asn Pro  His Ser Gly Lys Glu  Tyr Phe Arg 
    3125                 3130                 3135             


Val Pro  Asp Ser Ala Thr Phe  Ser Ile Cys Pro Gly  Gly Glu Gln 
    3140                 3145                 3150             


Pro Ala  Met Lys Ser Ser Ser  Leu Pro Cys Trp Asp  Leu Met Pro 
    3155                 3160                 3165             


Asp Ile  Ser Gln Ser Val Leu  Asp Ala Ser Leu Leu  Gln Lys Gln 
    3170                 3175                 3180             


Ile Met  Leu Gly Phe Ser Pro  Ala Pro Gly Ala Asp  Ser Ser Gln 
    3185                 3190                 3195             


Cys Trp  Ser Leu Pro Ala Ile  Val Arg Pro Glu Phe  Pro Arg Gln 
    3200                 3205                 3210             


Ser Val  Ala Val Pro Leu Gly  Asn Phe Arg Glu Asn  Gly Phe Cys 
    3215                 3220                 3225             


Thr Arg  Ala Ile Val Leu Thr  Tyr Gln Glu His Leu  Gly Val Thr 
    3230                 3235                 3240             


Tyr Leu  Thr Leu Ser Glu Asp  Pro Ser Pro Arg Val  Ile Ile His 
    3245                 3250                 3255             


Asn Arg  Cys Pro Val Lys Met  Leu Ile Lys Glu Asn  Ile Lys Asp 
    3260                 3265                 3270             


Ile Pro  Lys Phe Glu Val Tyr  Cys Lys Lys Ile Pro  Ser Glu Cys 
    3275                 3280                 3285             


Ser Ile  His His Glu Leu Tyr  His Gln Ile Ser Ser  Tyr Pro Asp 
    3290                 3295                 3300             


Cys Lys  Thr Lys Asp Leu Leu  Pro Ser Leu Leu Leu  Arg Val Glu 
    3305                 3310                 3315             


Pro Leu  Asp Glu Val Thr Thr  Glu Trp Ser Asp Ala  Ile Asp Ile 
    3320                 3325                 3330             


Asn Ser  Gln Gly Thr Gln Val  Val Phe Leu Thr Gly  Phe Gly Tyr 
    3335                 3340                 3345             


Val Tyr  Val Asp Val Val His  Gln Cys Gly Thr Val  Phe Ile Thr 
    3350                 3355                 3360             


Val Ala  Pro Glu Gly Lys Ala  Gly Pro Ile Leu Thr  Asn Thr Asn 
    3365                 3370                 3375             


Arg Ala  Pro Glu Lys Ile Val  Thr Phe Lys Met Phe  Ile Thr Gln 
    3380                 3385                 3390             


Leu Ser  Leu Ala Val Phe Asp  Asp Leu Thr His His  Lys Ala Ser 
    3395                 3400                 3405             


Ala Glu  Leu Leu Arg Leu Thr  Leu Asp Asn Ile Phe  Leu Cys Val 
    3410                 3415                 3420             


Ala Pro  Gly Ala Gly Pro Leu  Pro Gly Glu Glu Pro  Val Ala Ala 
    3425                 3430                 3435             


Leu Phe  Glu Leu Tyr Cys Val  Glu Ile Cys Cys Gly  Asp Leu Gln 
    3440                 3445                 3450             


Leu Asp  Asn Gln Leu Tyr Asn  Lys Ser Asn Phe His  Phe Ala Val 
    3455                 3460                 3465             


Leu Val  Cys Gln Gly Glu Lys  Ala Glu Pro Ile Gln  Cys Ser Lys 
    3470                 3475                 3480             


Met Gln  Ser Leu Leu Ile Ser  Asn Lys Glu Leu Glu  Glu Tyr Lys 
    3485                 3490                 3495             


Glu Lys  Cys Phe Ile Lys Leu  Cys Ile Thr Leu Asn  Glu Gly Lys 
    3500                 3505                 3510             


Ser Ile  Leu Cys Asp Ile Asn  Glu Phe Ser Phe Glu  Leu Lys Pro 
    3515                 3520                 3525             


Ala Arg  Leu Tyr Val Glu Asp  Thr Phe Val Tyr Tyr  Ile Lys Thr 
    3530                 3535                 3540             


Leu Phe  Asp Thr Tyr Leu Pro  Asn Ser Arg Leu Ala  Gly His Ser 
    3545                 3550                 3555             


Thr His  Leu Ser Gly Gly Lys  Gln Val Leu Pro Met  Gln Val Thr 
    3560                 3565                 3570             


Gln His  Ala Arg Ala Leu Val  Asn Pro Val Lys Leu  Arg Lys Leu 
    3575                 3580                 3585             


Val Ile  Gln Pro Val Asn Leu  Leu Val Ser Ile His  Ala Ser Leu 
    3590                 3595                 3600             


Lys Leu  Tyr Ile Ala Ser Asp  His Thr Pro Leu Ser  Phe Ser Val 
    3605                 3610                 3615             


Phe Glu  Arg Gly Pro Ile Phe  Thr Thr Ala Arg Gln  Leu Val His 
    3620                 3625                 3630             


Ala Leu  Ala Met His Tyr Ala  Ala Gly Ala Leu Phe  Arg Ala Gly 
    3635                 3640                 3645             


Trp Val  Val Gly Ser Leu Asp  Ile Leu Gly Ser Pro  Ala Ser Leu 
    3650                 3655                 3660             


Val Arg  Ser Ile Gly Asn Gly  Val Ala Asp Phe Phe  Arg Leu Pro 
    3665                 3670                 3675             


Tyr Glu  Gly Leu Thr Arg Gly  Pro Gly Ala Phe Val  Ser Gly Val 
    3680                 3685                 3690             


Ser Arg  Gly Thr Thr Ser Phe  Val Lys His Ile Ser  Lys Gly Thr 
    3695                 3700                 3705             


Leu Thr  Ser Ile Thr Asn Leu  Ala Thr Ser Leu Ala  Arg Asn Met 
    3710                 3715                 3720             


Asp Arg  Leu Ser Leu Asp Glu  Glu His Tyr Asn Arg  Gln Glu Glu 
    3725                 3730                 3735             


Trp Arg  Arg Gln Leu Pro Glu  Ser Leu Gly Glu Gly  Leu Arg Gln 
    3740                 3745                 3750             


Gly Leu  Ser Arg Leu Gly Ile  Ser Leu Leu Gly Ala  Ile Ala Gly 
    3755                 3760                 3765             


Ile Val  Asp Gln Pro Met Gln  Asn Phe Gln Lys Thr  Ser Glu Ala 
    3770                 3775                 3780             


Gln Ala  Ser Ala Gly His Lys  Ala Lys Gly Val Ile  Ser Gly Val 
    3785                 3790                 3795             


Gly Lys  Gly Ile Met Gly Val  Phe Thr Lys Pro Ile  Gly Gly Ala 
    3800                 3805                 3810             


Ala Glu  Leu Val Ser Gln Thr  Gly Tyr Gly Ile Leu  His Gly Ala 
    3815                 3820                 3825             


Gly Leu  Ser Gln Leu Pro Lys  Gln Arg His Gln Pro  Ser Asp Leu 
    3830                 3835                 3840             


His Ala  Asp Gln Ala Pro Asn  Ser His Val Lys Tyr  Val Trp Lys 
    3845                 3850                 3855             


Met Leu  Gln Ser Leu Gly Arg  Pro Glu Val His Met  Ala Leu Asp 
    3860                 3865                 3870             


Val Val  Leu Val Arg Gly Ser  Gly Gln Glu His Glu  Gly Cys Leu 
    3875                 3880                 3885             


Leu Leu  Thr Ser Glu Val Leu  Phe Val Val Ser Val  Ser Glu Asp 
    3890                 3895                 3900             


Thr Gln  Gln Gln Ala Phe Pro  Val Thr Glu Ile Asp  Cys Ala Gln 
    3905                 3910                 3915             


Asp Ser  Lys Gln Asn Asn Leu  Leu Thr Val Gln Leu  Lys Gln Pro 
    3920                 3925                 3930             


Arg Val  Ala Cys Asp Val Glu  Val Asp Gly Val Arg  Glu Arg Leu 
    3935                 3940                 3945             


Ser Glu  Gln Gln Tyr Asn Arg  Leu Val Asp Tyr Ile  Thr Lys Thr 
    3950                 3955                 3960             


Ser Cys  His Leu Ala Pro Ser  Cys Ser Ser Met Gln  Ile Pro Cys 
    3965                 3970                 3975             


Pro Val  Val Ala Ala Glu Pro  Pro Pro Ser Thr Val  Lys Thr Tyr 
    3980                 3985                 3990             


His Tyr  Leu Val Asp Pro His  Phe Ala Gln Val Phe  Leu Ser Lys 
    3995                 4000                 4005             


Phe Thr  Met Val Lys Asn Lys  Ala Leu Arg Lys Gly  Phe Pro 
    4010                 4015                 4020         


<210>  3900
<211>  863
<212>  PRT
<213>  homo sapiens

<400>  3900

Met Leu Glu Ser Tyr Val Thr Pro Ile Leu Met Ser Tyr Val Asn Arg 
1               5                   10                  15      


Tyr Ile Lys Asn Leu Lys Pro Ser Asp Leu Gln Leu Ser Leu Trp Gly 
            20                  25                  30          


Gly Asp Val Val Leu Ser Lys Leu Glu Leu Lys Leu Asp Val Leu Glu 
        35                  40                  45              


Gln Glu Leu Lys Leu Pro Phe Thr Phe Leu Ser Gly His Ile His Glu 
    50                  55                  60                  


Leu Arg Ile His Val Pro Trp Thr Lys Leu Gly Ser Glu Pro Val Val 
65                  70                  75                  80  


Ile Thr Ile Asn Thr Met Glu Cys Ile Leu Lys Leu Lys Asp Gly Ile 
                85                  90                  95      


Gln Asp Asp His Glu Ser Cys Gly Ser Asn Ser Thr Asn Arg Ser Thr 
            100                 105                 110         


Ala Glu Ser Thr Lys Ser Ser Ile Lys Pro Arg Arg Met Gln Gln Ala 
        115                 120                 125             


Ala Pro Thr Asp Pro Asp Leu Pro Pro Gly Tyr Val Gln Ser Leu Ile 
    130                 135                 140                 


Arg Arg Val Val Asn Asn Val Asn Ile Val Ile Asn Asn Leu Ile Leu 
145                 150                 155                 160 


Lys Tyr Val Glu Asp Asp Ile Val Leu Ser Val Asn Ile Thr Ser Ala 
                165                 170                 175     


Glu Cys Tyr Thr Val Gly Glu Leu Trp Asp Arg Ala Phe Met Asp Ile 
            180                 185                 190         


Ser Ala Thr Asp Leu Val Leu Arg Lys Val Ile Asn Phe Ser Asp Cys 
        195                 200                 205             


Thr Val Cys Leu Asp Lys Arg Asn Ala Ser Gly Lys Ile Glu Phe Tyr 
    210                 215                 220                 


Gln Asp Pro Leu Leu Tyr Lys Cys Ser Phe Arg Thr Arg Leu His Phe 
225                 230                 235                 240 


Thr Tyr Glu Asn Leu Asn Ser Lys Met Pro Ser Val Ile Lys Ile His 
                245                 250                 255     


Thr Leu Val Glu Ser Leu Lys Leu Ser Ile Thr Asp Gln Gln Leu Pro 
            260                 265                 270         


Met Phe Ile Arg Ile Met Gln Leu Gly Ile Ala Leu Tyr Tyr Gly Glu 
        275                 280                 285             


Ile Gly Asn Phe Lys Glu Gly Glu Ile Glu Asp Leu Thr Cys His Asn 
    290                 295                 300                 


Lys Asp Met Leu Gly Asn Ile Thr Gly Ser Glu Asp Glu Thr Arg Ile 
305                 310                 315                 320 


Asp Met Gln Tyr Pro Ala Gln His Lys Gly Gln Glu Leu Tyr Ser Gln 
                325                 330                 335     


Gln Asp Glu Glu Gln Pro Gln Gly Trp Val Ser Trp Ala Trp Ser Phe 
            340                 345                 350         


Val Pro Ala Ile Val Ser Tyr Asp Asp Gly Glu Glu Asp Phe Val Gly 
        355                 360                 365             


Asn Asp Pro Ala Ser Thr Met His Gln Gln Lys Ala Gln Thr Leu Lys 
    370                 375                 380                 


Asp Pro Ile Val Ser Ile Gly Phe Tyr Cys Thr Lys Ala Thr Val Thr 
385                 390                 395                 400 


Phe Lys Leu Thr Glu Met Gln Val Glu Ser Ser Tyr Tyr Ser Pro Gln 
                405                 410                 415     


Lys Val Lys Ser Lys Glu Val Leu Cys Trp Glu Gln Glu Gly Thr Thr 
            420                 425                 430         


Val Glu Ala Leu Met Met Gly Glu Pro Phe Phe Asp Cys Gln Ile Gly 
        435                 440                 445             


Phe Val Gly Cys Arg Ala Met Cys Leu Lys Gly Ile Met Gly Val Lys 
    450                 455                 460                 


Asp Phe Glu Glu Asn Met Asn Arg Ser Glu Thr Glu Ala Cys Phe Phe 
465                 470                 475                 480 


Ile Cys Gly Asp Asn Leu Ser Thr Lys Gly Phe Thr Tyr Leu Thr Asn 
                485                 490                 495     


Ser Leu Phe Asp Tyr Arg Ser Pro Glu Asn Asn Gly Thr Arg Ala Glu 
            500                 505                 510         


Phe Ile Leu Asp Ser Thr His His Lys Glu Thr Tyr Thr Glu Ile Ala 
        515                 520                 525             


Gly Met Gln Arg Phe Gly Ala Phe Tyr Met Asp Tyr Leu Tyr Thr Met 
    530                 535                 540                 


Glu Asn Thr Ser Gly Lys Gly Ser Thr Asn Gln Gln Asp Phe Ser Ser 
545                 550                 555                 560 


Gly Lys Ser Glu Asp Leu Gly Thr Val Gln Glu Lys Ser Thr Lys Ser 
                565                 570                 575     


Leu Val Ile Gly Pro Leu Asp Phe Arg Leu Asp Ser Ser Ala Val His 
            580                 585                 590         


Arg Ile Leu Lys Met Ile Val Cys Ala Leu Glu His Glu Tyr Glu Pro 
        595                 600                 605             


Tyr Ser Arg Leu Lys Ser Asp Ile Lys Asp Glu Asn Glu Thr Ile Leu 
    610                 615                 620                 


Asn Pro Glu Glu Val Ala Leu Leu Glu Glu Tyr Ile Pro Thr Arg His 
625                 630                 635                 640 


Thr Ser Val Thr Leu Leu Lys Cys Thr Cys Thr Ile Ser Met Ala Glu 
                645                 650                 655     


Phe Asn Leu Leu Asp His Leu Leu Pro Val Ile Met Gly Glu Lys Asn 
            660                 665                 670         


Ser Ser Asn Phe Met Asn Thr Thr Asn Phe Gln Ser Leu Arg Pro Leu 
        675                 680                 685             


Pro Ser Ile Arg Ile Leu Val Asp Lys Ile Asn Leu Glu His Ser Val 
    690                 695                 700                 


Pro Met Tyr Ala Glu Gln Leu Val His Val Val Ser Ser Leu Thr Gln 
705                 710                 715                 720 


Pro Ser Asp Asn Leu Leu His Tyr Cys Tyr Val His Cys Tyr Leu Lys 
                725                 730                 735     


Ile Phe Gly Phe Gln Ala Gly Leu Thr Ser Leu Asp Cys Ser Gly Ser 
            740                 745                 750         


Tyr Cys Leu Pro Val Pro Val Ile Pro Ser Phe Ser Thr Ala Leu Tyr 
        755                 760                 765             


Gly Lys Leu Leu Lys Leu Pro Thr Cys Trp Thr Lys Arg Ser Gln Ile 
    770                 775                 780                 


Ala Ile Thr Glu Gly Ile Phe Glu Leu Pro Asn Leu Thr Ile Gln Ala 
785                 790                 795                 800 


Thr Arg Ala Gln Thr Leu Leu Leu Gln Ala Ile Tyr Gln Ser Trp Ser 
                805                 810                 815     


His Leu Gly Asn Val Ser Ser Ser Ala Val Ile Glu Ala Leu Ile Asn 
            820                 825                 830         


Glu Ile Phe Leu Ser Ile Glu Ile Gly Ser Cys Tyr Val Ala Gln Val 
        835                 840                 845             


Asp Leu Glu Leu Leu Ala Ser Asn Asp Pro Pro Thr Ser Thr Ser 
    850                 855                 860             


<210>  3901
<211>  415
<212>  PRT
<213>  homo sapiens

<400>  3901

Met Leu Glu Ser Tyr Val Thr Pro Ile Leu Met Ser Tyr Val Asn Arg 
1               5                   10                  15      


Tyr Ile Lys Asn Leu Lys Pro Ser Asp Leu Gln Leu Ser Leu Trp Gly 
            20                  25                  30          


Gly Asp Val Val Leu Ser Lys Leu Glu Leu Lys Leu Asp Val Leu Glu 
        35                  40                  45              


Gln Glu Leu Lys Leu Pro Phe Thr Phe Leu Ser Gly His Ile His Glu 
    50                  55                  60                  


Leu Arg Ile His Val Pro Trp Thr Lys Leu Gly Ser Glu Pro Val Val 
65                  70                  75                  80  


Ile Thr Ile Asn Thr Met Glu Cys Ile Leu Lys Leu Lys Asp Gly Ile 
                85                  90                  95      


Gln Asp Asp His Glu Ser Cys Gly Ser Asn Ser Thr Asn Arg Ser Thr 
            100                 105                 110         


Ala Glu Ser Thr Lys Ser Ser Ile Lys Pro Arg Arg Met Gln Gln Ala 
        115                 120                 125             


Ala Pro Thr Asp Pro Asp Leu Pro Pro Gly Tyr Val Gln Ser Leu Ile 
    130                 135                 140                 


Arg Arg Val Val Asn Asn Val Asn Ile Val Ile Asn Asn Leu Ile Leu 
145                 150                 155                 160 


Lys Tyr Val Glu Asp Asp Ile Val Leu Ser Val Asn Ile Thr Ser Ala 
                165                 170                 175     


Glu Cys Tyr Thr Val Gly Glu Leu Trp Asp Arg Ala Phe Met Asp Ile 
            180                 185                 190         


Ser Ala Thr Asp Leu Val Leu Arg Lys Val Ile Asn Phe Ser Asp Cys 
        195                 200                 205             


Thr Val Cys Leu Asp Lys Arg Asn Ala Ser Gly Lys Ile Glu Phe Tyr 
    210                 215                 220                 


Gln Asp Pro Leu Leu Tyr Lys Cys Ser Phe Arg Thr Arg Leu His Phe 
225                 230                 235                 240 


Thr Tyr Glu Asn Leu Asn Ser Lys Met Pro Ser Val Ile Lys Ile His 
                245                 250                 255     


Thr Leu Val Glu Ser Leu Lys Leu Ser Ile Thr Asp Gln Gln Leu Pro 
            260                 265                 270         


Met Phe Ile Arg Ile Met Gln Leu Gly Ile Ala Leu Tyr Tyr Gly Glu 
        275                 280                 285             


Ile Gly Asn Phe Lys Glu Gly Glu Ile Glu Asp Leu Thr Cys His Asn 
    290                 295                 300                 


Lys Asp Met Leu Gly Asn Ile Thr Gly Ser Glu Asp Glu Thr Arg Ile 
305                 310                 315                 320 


Asp Met Gln Tyr Pro Ala Gln His Lys Gly Gln Glu Leu Tyr Ser Gln 
                325                 330                 335     


Gln Asp Glu Glu Gln Pro Gln Gly Trp Val Ser Trp Ala Trp Ser Phe 
            340                 345                 350         


Val Pro Ala Ile Val Ser Tyr Asp Asp Gly Glu Glu Asp Phe Val Gly 
        355                 360                 365             


Asn Asp Pro Ala Ser Thr Met His Gln Gln Lys Ala Gln Thr Leu Lys 
    370                 375                 380                 


Asp Pro Ile Val Ser Ile Gly Phe Tyr Cys Thr Lys Ala Thr Val Thr 
385                 390                 395                 400 


Phe Lys Val Gly Leu Phe Ser Cys Cys Leu Tyr Leu Tyr Gln Leu 
                405                 410                 415 


<210>  3902
<211>  327
<212>  PRT
<213>  homo sapiens

<400>  3902

Met Ser Phe Leu Gly Gly Phe Phe Gly Pro Ile Cys Glu Ile Asp Ile 
1               5                   10                  15      


Val Leu Asn Asp Gly Glu Thr Arg Lys Met Ala Glu Met Lys Thr Glu 
            20                  25                  30          


Asp Gly Lys Val Glu Lys His Tyr Leu Phe Tyr Asp Gly Glu Ser Val 
        35                  40                  45              


Ser Gly Lys Val Asn Leu Ala Phe Lys Gln Pro Gly Lys Arg Leu Glu 
    50                  55                  60                  


His Gln Gly Ile Arg Ile Glu Phe Val Gly Gln Ile Glu Leu Phe Asn 
65                  70                  75                  80  


Asp Lys Ser Asn Thr His Glu Phe Val Asn Leu Val Lys Glu Leu Ala 
                85                  90                  95      


Leu Pro Gly Glu Leu Thr Gln Ser Arg Ser Tyr Asp Phe Glu Phe Met 
            100                 105                 110         


Gln Val Glu Lys Pro Tyr Glu Ser Tyr Ile Gly Ala Asn Val Arg Leu 
        115                 120                 125             


Arg Tyr Phe Leu Lys Val Thr Ile Val Arg Arg Leu Thr Asp Leu Val 
    130                 135                 140                 


Lys Glu Tyr Asp Leu Ile Val His Gln Leu Ala Thr Tyr Pro Asp Val 
145                 150                 155                 160 


Asn Asn Ser Ile Lys Met Glu Val Gly Ile Glu Asp Cys Leu His Ile 
                165                 170                 175     


Glu Phe Glu Tyr Asn Lys Ser Lys Tyr His Leu Lys Asp Val Ile Val 
            180                 185                 190         


Gly Lys Ile Tyr Phe Leu Leu Val Arg Ile Lys Ile Gln His Met Glu 
        195                 200                 205             


Leu Gln Leu Ile Lys Lys Glu Ile Thr Gly Ile Gly Pro Ser Thr Thr 
    210                 215                 220                 


Thr Glu Thr Glu Thr Ile Ala Lys Tyr Glu Ile Met Asp Gly Ala Pro 
225                 230                 235                 240 


Val Lys Gly Glu Ser Ile Pro Ile Arg Leu Phe Leu Ala Gly Tyr Asp 
                245                 250                 255     


Pro Thr Pro Thr Met Arg Asp Val Asn Lys Lys Phe Ser Val Arg Tyr 
            260                 265                 270         


Phe Leu Asn Leu Val Leu Val Asp Glu Glu Asp Arg Arg Tyr Phe Lys 
        275                 280                 285             


Gln Gln Glu Ile Ile Leu Trp Arg Lys Ala Pro Glu Lys Leu Arg Lys 
    290                 295                 300                 


Gln Arg Thr Asn Phe His Gln Arg Phe Glu Ser Pro Glu Ser Gln Ala 
305                 310                 315                 320 


Ser Ala Glu Gln Pro Glu Met 
                325         


<210>  3903
<211>  251
<212>  PRT
<213>  homo sapiens

<400>  3903

Met Ser Phe Leu Gly Gly Phe Phe Gly Pro Ile Cys Glu Ile Asp Ile 
1               5                   10                  15      


Val Leu Asn Asp Gly Glu Thr Arg Lys Met Ala Glu Met Lys Thr Glu 
            20                  25                  30          


Asp Gly Lys Val Glu Lys His Tyr Leu Phe Tyr Asp Gly Glu Ser Val 
        35                  40                  45              


Ser Gly Lys Val Asn Leu Ala Phe Lys Gln Pro Gly Lys Arg Leu Glu 
    50                  55                  60                  


His Gln Gly Ile Arg Ile Glu Phe Val Gly Gln Ile Glu Leu Phe Asn 
65                  70                  75                  80  


Asp Lys Ser Asn Thr His Glu Phe Val Asn Leu Val Lys Glu Leu Ala 
                85                  90                  95      


Leu Pro Gly Glu Leu Thr Gln Ser Arg Ser Tyr Asp Phe Glu Phe Met 
            100                 105                 110         


Gln Val Glu Lys Pro Tyr Glu Ser Tyr Ile Gly Ala Asn Val Arg Leu 
        115                 120                 125             


Arg Tyr Phe Leu Lys Val Thr Ile Val Arg Arg Leu Thr Asp Leu Val 
    130                 135                 140                 


Lys Glu Tyr Asp Leu Ile Val His Gln Leu Ala Thr Tyr Pro Asp Val 
145                 150                 155                 160 


Asn Asn Ser Ile Lys Met Glu Val Gly Ile Glu Asp Cys Leu His Ile 
                165                 170                 175     


Glu Phe Glu Tyr Asn Lys Ser Lys Tyr His Leu Lys Asp Val Ile Val 
            180                 185                 190         


Gly Lys Ile Tyr Phe Leu Leu Val Arg Ile Lys Ile Gln His Met Glu 
        195                 200                 205             


Leu Gln Leu Ile Lys Lys Glu Ile Thr Gly Ile Gly Pro Ser Thr Thr 
    210                 215                 220                 


Thr Glu Thr Glu Thr Ile Ala Lys Tyr Glu Ile Met Asp Gly Ala Pro 
225                 230                 235                 240 


Val Lys Gly Asp Asn Phe Met Glu Lys Ser Ser 
                245                 250     


<210>  3904
<211>  285
<212>  PRT
<213>  homo sapiens

<400>  3904

Met Ala Gly Ala Gly Ser Glu Ala Arg Phe Ala Gly Leu Ser Leu Val 
1               5                   10                  15      


Gln Leu Asn Glu Leu Leu Glu Asp Glu Gly Gln Leu Thr Glu Met Val 
            20                  25                  30          


Gln Lys Met Glu Glu Thr Gln Asn Val Gln Leu Asn Lys Glu Met Thr 
        35                  40                  45              


Leu Ala Ser Asn Arg Ser Leu Ala Glu Gly Asn Leu Leu Tyr Gln Pro 
    50                  55                  60                  


Gln Leu Asp Thr Leu Lys Ala Arg Leu Thr Gln Lys Tyr Gln Glu Leu 
65                  70                  75                  80  


Gln Val Leu Phe Glu Ala Tyr Gln Ile Lys Lys Thr Lys Leu Asp Arg 
                85                  90                  95      


Gln Ser Ser Ser Ala Ser Leu Glu Thr Leu Leu Ala Leu Leu Gln Ala 
            100                 105                 110         


Glu Gly Ala Lys Ile Glu Glu Asp Thr Glu Asn Met Ala Glu Lys Phe 
        115                 120                 125             


Leu Asp Gly Glu Leu Pro Leu Asp Ser Phe Ile Asp Val Tyr Gln Ser 
    130                 135                 140                 


Lys Arg Lys Leu Ala His Met Arg Arg Val Lys Ile Glu Lys Leu Gln 
145                 150                 155                 160 


Glu Met Val Leu Lys Gly Gln Arg Leu Pro Gln Ala Leu Ala Pro Leu 
                165                 170                 175     


Pro Pro Arg Leu Pro Glu Leu Ala Pro Thr Ala Pro Leu Pro Tyr Pro 
            180                 185                 190         


Ala Pro Glu Ala Ser Gly Pro Pro Ala Val Ala Pro Arg Arg Ile Pro 
        195                 200                 205             


Pro Pro Pro Pro Pro Val Pro Ala Gly Arg Leu Ala Thr Pro Phe Thr 
    210                 215                 220                 


Ala Ala Met Ser Ser Gly Gln Ala Val Pro Tyr Pro Gly Leu Gln Cys 
225                 230                 235                 240 


Pro Pro Leu Pro Pro Arg Val Gly Leu Pro Thr Gln Gln Gly Phe Ser 
                245                 250                 255     


Ser Gln Phe Val Ser Pro Tyr Pro Pro Pro Leu Pro Gln Arg Pro Pro 
            260                 265                 270         


Pro Arg Leu Pro Pro His Gln Pro Gly Phe Ile Leu Gln 
        275                 280                 285 


<210>  3905
<211>  244
<212>  PRT
<213>  homo sapiens

<400>  3905

Met Glu Leu Thr Ile Phe Ile Leu Arg Leu Ala Ile Tyr Ile Leu Thr 
1               5                   10                  15      


Phe Pro Leu Tyr Leu Leu Asn Phe Leu Gly Leu Trp Ser Trp Ile Cys 
            20                  25                  30          


Lys Lys Trp Phe Pro Tyr Phe Leu Val Arg Phe Thr Val Ile Tyr Asn 
        35                  40                  45              


Glu Gln Met Ala Ser Lys Lys Arg Glu Leu Phe Ser Asn Leu Gln Glu 
    50                  55                  60                  


Phe Ala Gly Pro Ser Gly Lys Leu Ser Leu Leu Glu Val Gly Cys Gly 
65                  70                  75                  80  


Thr Gly Ala Asn Phe Lys Phe Tyr Pro Pro Gly Cys Arg Val Thr Cys 
                85                  90                  95      


Ile Asp Pro Asn Pro Asn Phe Glu Lys Phe Leu Ile Lys Ser Ile Ala 
            100                 105                 110         


Glu Asn Arg His Leu Gln Phe Glu Arg Phe Val Val Ala Ala Gly Glu 
        115                 120                 125             


Asn Met His Gln Val Ala Asp Gly Ser Val Asp Val Val Val Cys Thr 
    130                 135                 140                 


Leu Val Leu Cys Ser Val Lys Asn Gln Glu Arg Ile Leu Arg Glu Val 
145                 150                 155                 160 


Cys Arg Val Leu Arg Pro Gly Gly Ala Phe Tyr Phe Met Glu His Val 
                165                 170                 175     


Ala Ala Glu Cys Ser Thr Trp Asn Tyr Phe Trp Gln Gln Val Leu Asp 
            180                 185                 190         


Pro Ala Trp His Leu Leu Phe Asp Gly Cys Asn Leu Thr Arg Glu Ser 
        195                 200                 205             


Trp Lys Ala Leu Glu Arg Ala Ser Phe Ser Lys Leu Lys Leu Gln His 
    210                 215                 220                 


Ile Gln Ala Pro Leu Ser Trp Glu Leu Val Arg Pro His Ile Tyr Gly 
225                 230                 235                 240 


Tyr Ala Val Lys 
                


<210>  3906
<211>  354
<212>  PRT
<213>  homo sapiens

<400>  3906

Met Ala His Ser Pro Val Ala Val Gln Val Pro Gly Met Gln Asn Asn 
1               5                   10                  15      


Ile Ala Asp Pro Glu Glu Leu Phe Thr Lys Leu Glu Arg Ile Gly Lys 
            20                  25                  30          


Gly Ser Phe Gly Glu Val Phe Lys Gly Ile Asp Asn Arg Thr Gln Gln 
        35                  40                  45              


Val Val Ala Ile Lys Ile Ile Asp Leu Glu Glu Ala Glu Asp Glu Ile 
    50                  55                  60                  


Glu Asp Ile Gln Gln Glu Ile Thr Val Leu Ser Gln Cys Asp Ser Ser 
65                  70                  75                  80  


Tyr Val Thr Lys Tyr Tyr Gly Ser Tyr Leu Lys Gly Ser Lys Leu Trp 
                85                  90                  95      


Ile Ile Met Glu Tyr Leu Gly Gly Gly Ser Ala Leu Asp Leu Leu Arg 
            100                 105                 110         


Ala Gly Pro Phe Asp Glu Phe Gln Ile Ala Thr Met Leu Lys Glu Ile 
        115                 120                 125             


Leu Lys Gly Leu Asp Tyr Leu His Ser Glu Lys Lys Ile His Arg Asp 
    130                 135                 140                 


Ile Lys Ala Ala Asn Val Leu Leu Ser Glu Gln Gly Asp Val Lys Leu 
145                 150                 155                 160 


Ala Asp Phe Gly Val Ala Gly Gln Leu Thr Asp Thr Gln Ile Lys Arg 
                165                 170                 175     


Asn Thr Phe Val Gly Thr Pro Phe Trp Met Ala Pro Glu Val Ile Gln 
            180                 185                 190         


Gln Ser Ala Tyr Asp Ser Lys Arg Pro Thr Ala Lys Glu Leu Leu Lys 
        195                 200                 205             


His Lys Phe Ile Val Lys Asn Ser Lys Lys Thr Ser Tyr Leu Thr Glu 
    210                 215                 220                 


Leu Ile Asp Arg Phe Lys Arg Trp Lys Ala Glu Gly His Ser Asp Asp 
225                 230                 235                 240 


Glu Ser Asp Ser Glu Gly Ser Asp Ser Glu Ser Thr Ser Arg Glu Asn 
                245                 250                 255     


Asn Thr His Pro Glu Trp Ser Phe Thr Thr Val Arg Lys Lys Pro Asp 
            260                 265                 270         


Pro Lys Lys Val Gln Asn Gly Ala Glu Gln Asp Leu Val Gln Thr Leu 
        275                 280                 285             


Ser Cys Leu Ser Met Ile Ile Thr Pro Ala Phe Ala Glu Leu Lys Gln 
    290                 295                 300                 


Gln Asp Glu Asn Asn Ala Ser Arg Asn Gln Ala Ile Glu Glu Leu Glu 
305                 310                 315                 320 


Lys Ser Ile Ala Val Ala Glu Ala Ala Cys Pro Gly Ile Thr Asp Lys 
                325                 330                 335     


Met Val Lys Lys Leu Ile Glu Lys Phe Gln Lys Cys Ser Ala Asp Glu 
            340                 345                 350         


Ser Pro 
        


<210>  3907
<211>  303
<212>  PRT
<213>  homo sapiens

<400>  3907

Met Ala Glu Val Ala Arg Gln Ala Gln Thr Ser Gln Glu Pro Tyr His 
1               5                   10                  15      


Asp Lys Ala Arg Glu His Pro Asp Asp Gly Lys His Pro Asp Gly Gly 
            20                  25                  30          


Leu Tyr Asn Lys Gly Pro Ser Tyr Ser Ser Tyr Ser Gly Tyr Ile Met 
        35                  40                  45              


Met Pro Asn Met Asn Asn Asp Pro Tyr Met Ser Asn Gly Ser Leu Ser 
    50                  55                  60                  


Pro Pro Ile Pro Arg Thr Ser Asn Lys Val Pro Val Val Gln Pro Ser 
65                  70                  75                  80  


His Ala Val His Pro Leu Thr Pro Leu Ile Thr Tyr Ser Asp Glu His 
                85                  90                  95      


Phe Ser Pro Gly Ser His Pro Ser His Ile Pro Ser Asp Val Asn Ser 
            100                 105                 110         


Lys Gln Gly Met Ser Arg His Pro Pro Ala Pro Asp Ile Pro Thr Phe 
        115                 120                 125             


Tyr Pro Leu Ser Pro Gly Gly Val Gly Gln Ile Thr Pro Pro Leu Gly 
    130                 135                 140                 


Trp Phe Ser His His Met Ile Pro Gly Pro Pro Gly Pro His Thr Thr 
145                 150                 155                 160 


Gly Ile Pro His Pro Ala Ile Val Thr Pro Gln Val Lys Gln Glu His 
                165                 170                 175     


Pro His Thr Asp Ser Asp Leu Met His Val Lys Pro Gln His Glu Gln 
            180                 185                 190         


Arg Lys Glu Gln Glu Pro Lys Arg Pro His Ile Lys Lys Pro Leu Asn 
        195                 200                 205             


Ala Phe Met Leu Tyr Met Lys Glu Met Arg Ala Asn Val Val Ala Glu 
    210                 215                 220                 


Cys Thr Leu Lys Glu Ser Ala Ala Ile Asn Gln Ile Leu Gly Arg Arg 
225                 230                 235                 240 


Trp His Ala Leu Ser Arg Glu Glu Gln Ala Lys Tyr Tyr Glu Leu Ala 
                245                 250                 255     


Arg Lys Glu Arg Gln Leu His Met Gln Leu Tyr Pro Gly Trp Ser Ala 
            260                 265                 270         


Arg Asp Asn Tyr Gly Lys Lys Lys Lys Arg Lys Arg Glu Lys Leu Gln 
        275                 280                 285             


Glu Ser Ala Ser Gly Thr Gly Pro Arg Met Thr Ala Ala Tyr Ile 
    290                 295                 300             


<210>  3908
<211>  353
<212>  PRT
<213>  homo sapiens

<400>  3908

Met Asp Glu Thr Val Ala Glu Phe Ile Lys Arg Thr Ile Leu Lys Ile 
1               5                   10                  15      


Pro Met Asn Glu Leu Thr Thr Ile Leu Lys Ala Trp Asp Phe Leu Ser 
            20                  25                  30          


Glu Asn Gln Leu Gln Thr Val Asn Phe Arg Gln Arg Lys Glu Ser Val 
        35                  40                  45              


Val Gln His Leu Ile His Leu Cys Glu Glu Lys Arg Ala Ser Ile Ser 
    50                  55                  60                  


Asp Ala Ala Leu Leu Asp Ile Ile Tyr Met Gln Phe His Gln His Gln 
65                  70                  75                  80  


Lys Val Trp Glu Val Phe Gln Met Ser Lys Gly Pro Gly Glu Asp Val 
                85                  90                  95      


Asp Leu Phe Asp Met Lys Gln Phe Lys Asn Ser Phe Lys Lys Ile Leu 
            100                 105                 110         


Gln Arg Ala Leu Lys Asn Val Thr Val Ser Phe Arg Glu Thr Glu Glu 
        115                 120                 125             


Asn Ala Val Trp Ile Arg Ile Ala Trp Gly Thr Gln Tyr Thr Lys Pro 
    130                 135                 140                 


Asn Gln Tyr Lys Pro Thr Tyr Val Val Tyr Tyr Ser Gln Thr Pro Tyr 
145                 150                 155                 160 


Ala Phe Thr Ser Ser Ser Met Leu Arg Arg Asn Thr Pro Leu Leu Gly 
                165                 170                 175     


Gln Ala Leu Thr Ile Ala Ser Lys His His Gln Ile Val Lys Met Asp 
            180                 185                 190         


Leu Arg Ser Arg Tyr Leu Asp Ser Leu Lys Ala Ile Val Phe Lys Gln 
        195                 200                 205             


Tyr Asn Gln Thr Phe Glu Thr His Asn Ser Thr Thr Pro Leu Gln Glu 
    210                 215                 220                 


Arg Ser Leu Gly Leu Asp Ile Asn Met Asp Ser Arg Ile Ile His Glu 
225                 230                 235                 240 


Asn Ile Val Glu Lys Glu Arg Val Gln Arg Ile Thr Gln Glu Thr Phe 
                245                 250                 255     


Gly Asp Tyr Pro Gln Pro Gln Leu Glu Phe Ala Gln Tyr Lys Leu Glu 
            260                 265                 270         


Thr Lys Phe Lys Ser Gly Leu Asn Gly Ser Ile Leu Ala Glu Arg Glu 
        275                 280                 285             


Glu Pro Leu Arg Cys Leu Ile Lys Phe Ser Ser Pro His Leu Leu Glu 
    290                 295                 300                 


Ala Leu Lys Ser Leu Ala Pro Ala Ala Leu Val Cys Arg Ile Gln Lys 
305                 310                 315                 320 


Leu Leu Cys Tyr Ser Gly Ser His Ser Gln Gly Thr Gln Asp Pro Ser 
                325                 330                 335     


Ser Trp Gln Lys Asp Leu Tyr Leu Leu Phe Val Pro Leu Tyr Pro Arg 
            340                 345                 350         


Cys 
    


<210>  3909
<211>  1624
<212>  PRT
<213>  homo sapiens

<400>  3909

Met Ala Gly Gln Gly Asp Cys Cys Val Lys Val Ala Val Arg Ile Arg 
1               5                   10                  15      


Pro Gln Leu Ser Lys Glu Lys Ile Glu Gly Cys His Ile Cys Thr Ser 
            20                  25                  30          


Val Thr Pro Gly Glu Pro Gln Val Leu Leu Gly Lys Asp Lys Ala Phe 
        35                  40                  45              


Thr Tyr Asp Phe Val Phe Asp Leu Asp Thr Trp Gln Glu Gln Ile Tyr 
    50                  55                  60                  


Ser Thr Cys Val Ser Lys Leu Ile Glu Gly Cys Phe Glu Gly Tyr Asn 
65                  70                  75                  80  


Ala Thr Val Leu Ala Tyr Gly Gln Thr Gly Ala Gly Lys Thr Tyr Thr 
                85                  90                  95      


Met Gly Thr Gly Phe Asp Met Ala Thr Ser Glu Glu Glu Gln Gly Ile 
            100                 105                 110         


Ile Pro Arg Ala Ile Ala His Leu Phe Gly Gly Ile Ala Glu Arg Lys 
        115                 120                 125             


Arg Arg Ala Gln Glu Gln Gly Val Ala Gly Pro Glu Phe Lys Val Ser 
    130                 135                 140                 


Ala Gln Phe Leu Glu Leu Tyr Asn Glu Glu Ile Leu Asp Leu Phe Asp 
145                 150                 155                 160 


Ser Thr Arg Asp Pro Asp Thr Arg His Arg Arg Ser Asn Ile Lys Ile 
                165                 170                 175     


His Glu Asp Ala Asn Gly Gly Ile Tyr Thr Thr Gly Val Thr Ser Arg 
            180                 185                 190         


Leu Ile His Ser Gln Glu Glu Leu Ile Gln Cys Leu Lys Gln Gly Ala 
        195                 200                 205             


Leu Ser Arg Thr Thr Ala Ser Thr Gln Met Asn Val Gln Ser Ser Arg 
    210                 215                 220                 


Ser His Ala Ile Phe Thr Ile His Leu Cys Gln Met Arg Met Cys Thr 
225                 230                 235                 240 


Gln Pro Asp Leu Val Asn Glu Ala Val Thr Gly Leu Pro Asp Gly Thr 
                245                 250                 255     


Pro Pro Ser Ser Glu Tyr Glu Thr Leu Thr Ala Lys Phe His Phe Val 
            260                 265                 270         


Asp Leu Ala Gly Ser Glu Arg Leu Lys Arg Thr Gly Ala Thr Gly Glu 
        275                 280                 285             


Arg Ala Lys Glu Gly Ile Ser Ile Asn Cys Gly Leu Leu Ala Leu Gly 
    290                 295                 300                 


Asn Val Ile Ser Ala Leu Gly Asp Gln Ser Lys Lys Val Val His Val 
305                 310                 315                 320 


Pro Tyr Arg Asp Ser Lys Leu Thr Arg Leu Leu Gln Asp Ser Leu Gly 
                325                 330                 335     


Gly Asn Ser Gln Thr Ile Met Ile Ala Cys Val Ser Pro Ser Asp Arg 
            340                 345                 350         


Asp Phe Met Glu Thr Leu Asn Thr Leu Lys Tyr Ala Asn Arg Ala Arg 
        355                 360                 365             


Asn Ile Lys Asn Lys Val Val Val Asn Gln Asp Lys Thr Ser Gln Gln 
    370                 375                 380                 


Ile Ser Ala Leu Arg Ala Glu Ile Ala Arg Leu Gln Met Glu Leu Met 
385                 390                 395                 400 


Glu Tyr Lys Ala Gly Lys Arg Val Ile Gly Glu Asp Gly Ala Glu Gly 
                405                 410                 415     


Tyr Ser Asp Leu Phe Arg Glu Asn Ala Met Leu Gln Lys Glu Asn Gly 
            420                 425                 430         


Ala Leu Arg Leu Arg Val Lys Ala Met Gln Glu Ala Ile Asp Ala Ile 
        435                 440                 445             


Asn Asn Arg Val Thr Gln Leu Met Ser Gln Glu Ala Asn Leu Leu Leu 
    450                 455                 460                 


Ala Lys Ala Gly Asp Gly Asn Glu Ala Ile Gly Ala Leu Ile Gln Asn 
465                 470                 475                 480 


Tyr Ile Arg Glu Ile Glu Glu Leu Arg Thr Lys Leu Leu Glu Ser Glu 
                485                 490                 495     


Ala Met Asn Glu Ser Leu Arg Arg Ser Leu Ser Arg Ala Ser Ala Arg 
            500                 505                 510         


Ser Pro Tyr Ser Leu Gly Ala Ser Pro Ala Ala Pro Ala Phe Gly Gly 
        515                 520                 525             


Ser Pro Ala Ser Ser Met Glu Asp Ala Ser Glu Val Ile Arg Arg Ala 
    530                 535                 540                 


Lys Gln Asp Leu Glu Arg Leu Lys Lys Lys Glu Val Arg Gln Arg Arg 
545                 550                 555                 560 


Lys Ser Pro Glu Lys Glu Ala Phe Lys Lys Arg Ala Lys Leu Gln Gln 
                565                 570                 575     


Glu Asn Ser Glu Glu Thr Asp Glu Asn Glu Ala Glu Glu Glu Glu Glu 
            580                 585                 590         


Glu Arg Asp Glu Ser Gly Cys Glu Glu Glu Glu Gly Arg Glu Asp Glu 
        595                 600                 605             


Asp Glu Asp Ser Gly Ser Glu Glu Ser Leu Val Asp Ser Asp Ser Asp 
    610                 615                 620                 


Pro Glu Glu Lys Glu Val Asn Phe Gln Ala Asp Leu Ala Asp Leu Thr 
625                 630                 635                 640 


Cys Glu Ile Glu Ile Lys Gln Lys Leu Ile Asp Glu Leu Glu Asn Ser 
                645                 650                 655     


Gln Arg Arg Leu Gln Thr Leu Lys His Gln Tyr Glu Glu Lys Leu Ile 
            660                 665                 670         


Leu Leu Gln Asn Lys Ile Arg Asp Thr Gln Leu Glu Arg Asp Arg Val 
        675                 680                 685             


Leu Gln Asn Leu Ser Thr Met Glu Cys Tyr Thr Glu Glu Lys Ala Asn 
    690                 695                 700                 


Lys Ile Lys Ala Asp Tyr Glu Lys Arg Leu Arg Glu Met Asn Arg Asp 
705                 710                 715                 720 


Leu Gln Lys Leu Gln Ala Ala Gln Lys Glu His Ala Arg Leu Leu Lys 
                725                 730                 735     


Asn Gln Ser Arg Tyr Glu Arg Glu Leu Lys Lys Leu Gln Ala Glu Val 
            740                 745                 750         


Ala Glu Met Lys Lys Ala Lys Val Ala Leu Met Lys Gln Met Arg Glu 
        755                 760                 765             


Glu Gln Gln Arg Arg Arg Leu Val Glu Thr Lys Arg Asn Arg Glu Ile 
    770                 775                 780                 


Ala Gln Leu Lys Lys Glu Gln Arg Arg Gln Glu Phe Gln Ile Arg Ala 
785                 790                 795                 800 


Leu Glu Ser Gln Lys Arg Gln Gln Glu Met Val Leu Arg Arg Lys Thr 
                805                 810                 815     


Gln Glu Val Ser Ala Leu Arg Arg Leu Ala Lys Pro Met Ser Glu Arg 
            820                 825                 830         


Val Ala Gly Arg Ala Gly Leu Lys Pro Pro Met Leu Asp Ser Gly Ala 
        835                 840                 845             


Glu Val Ser Ala Ser Thr Thr Ser Ser Glu Ala Glu Ser Gly Ala Arg 
    850                 855                 860                 


Ser Val Ser Ser Ile Val Arg Gln Trp Asn Arg Lys Ile Asn His Phe 
865                 870                 875                 880 


Leu Gly Asp His Pro Ala Pro Thr Val Asn Gly Thr Arg Pro Ala Arg 
                885                 890                 895     


Lys Lys Phe Gln Lys Lys Gly Ala Ser Gln Ser Phe Ser Lys Ala Ala 
            900                 905                 910         


Arg Leu Lys Trp Gln Ser Leu Glu Arg Arg Ile Ile Asp Ile Val Met 
        915                 920                 925             


Gln Arg Met Thr Ile Val Asn Leu Glu Ala Asp Met Glu Arg Leu Ile 
    930                 935                 940                 


Lys Lys Arg Glu Glu Leu Phe Leu Leu Gln Glu Ala Leu Arg Arg Lys 
945                 950                 955                 960 


Arg Glu Arg Leu Gln Ala Glu Ser Pro Glu Glu Glu Lys Gly Leu Gln 
                965                 970                 975     


Glu Leu Ala Glu Glu Ile Glu Val Leu Ala Ala Asn Ile Asp Tyr Ile 
            980                 985                 990         


Asn Asp Gly Ile Thr Asp Cys Gln  Ala Thr Ile Val Gln  Leu Glu Glu 
        995                 1000                 1005             


Thr Lys  Glu Glu Leu Asp Ser  Thr Asp Thr Ser Val  Val Ile Ser 
    1010                 1015                 1020             


Ser Cys  Ser Leu Ala Glu Ala  Arg Leu Leu Leu Asp  Asn Phe Leu 
    1025                 1030                 1035             


Lys Ala  Ser Ile Asp Lys Gly  Leu Gln Val Ala Gln  Lys Glu Ala 
    1040                 1045                 1050             


Gln Ile  Arg Leu Leu Glu Gly  Arg Leu Arg Gln Thr  Asp Met Ala 
    1055                 1060                 1065             


Gly Ser  Ser Gln Asn His Leu  Leu Leu Asp Ala Leu  Arg Glu Lys 
    1070                 1075                 1080             


Ala Glu  Ala His Pro Glu Leu  Gln Ala Leu Ile Tyr  Asn Val Gln 
    1085                 1090                 1095             


Gln Glu  Asn Gly Tyr Ala Ser  Thr Asp Glu Glu Ile  Ser Glu Phe 
    1100                 1105                 1110             


Ser Glu  Gly Ser Phe Ser Gln  Ser Phe Thr Met Lys  Gly Ser Thr 
    1115                 1120                 1125             


Ser His  Asp Asp Phe Lys Phe  Lys Ser Glu Pro Lys  Leu Ser Ala 
    1130                 1135                 1140             


Gln Met  Lys Ala Val Ser Ala  Glu Cys Leu Gly Pro  Pro Leu Asp 
    1145                 1150                 1155             


Ile Ser  Thr Lys Asn Ile Thr  Lys Ser Leu Ala Ser  Leu Val Glu 
    1160                 1165                 1170             


Ile Lys  Glu Asp Gly Val Gly  Phe Ser Val Arg Asp  Pro Tyr Tyr 
    1175                 1180                 1185             


Arg Asp  Arg Val Ser Arg Thr  Val Ser Leu Pro Thr  Arg Gly Ser 
    1190                 1195                 1200             


Thr Phe  Pro Arg Gln Ser Arg  Ala Thr Glu Thr Ser  Pro Leu Thr 
    1205                 1210                 1215             


Arg Arg  Lys Ser Tyr Asp Arg  Gly Gln Pro Ile Arg  Ser Thr Asp 
    1220                 1225                 1230             


Val Gly  Phe Thr Pro Pro Ser  Ser Pro Pro Thr Arg  Pro Arg Asn 
    1235                 1240                 1245             


Asp Arg  Asn Val Phe Ser Arg  Leu Thr Ser Asn Gln  Ser Gln Gly 
    1250                 1255                 1260             


Ser Ala  Leu Asp Lys Gly Ile  Ile Ser Pro Val Gly  Gly Ala Lys 
    1265                 1270                 1275             


Gly Ala  Arg Thr Ala Pro Leu  Gln Cys Val Ser Met  Ala Glu Gly 
    1280                 1285                 1290             


His Thr  Lys Pro Ile Leu Cys  Leu Asp Ala Thr Asp  Glu Leu Leu 
    1295                 1300                 1305             


Phe Thr  Gly Ser Lys Asp Arg  Ser Cys Lys Met Trp  Asn Leu Val 
    1310                 1315                 1320             


Thr Gly  Gln Glu Ile Ala Ala  Leu Lys Gly His Pro  Asn Asn Val 
    1325                 1330                 1335             


Val Ser  Ile Lys Tyr Cys Ser  His Ser Gly Leu Val  Phe Ser Val 
    1340                 1345                 1350             


Ser Thr  Ser Tyr Ile Lys Val  Trp Asp Ile Arg Asp  Ser Ala Lys 
    1355                 1360                 1365             


Cys Ile  Arg Thr Leu Thr Ser  Ser Gly Gln Val Ile  Ser Gly Asp 
    1370                 1375                 1380             


Ala Cys  Ala Ala Thr Ser Thr  Arg Ala Ile Thr Ser  Ala Gln Gly 
    1385                 1390                 1395             


Glu His  Gln Ile Asn Gln Ile  Ala Leu Ser Pro Ser  Gly Thr Met 
    1400                 1405                 1410             


Leu Tyr  Ala Ala Ser Gly Asn  Ala Val Arg Ile Trp  Glu Leu Ser 
    1415                 1420                 1425             


Arg Phe  Gln Pro Val Gly Lys  Leu Thr Gly His Ile  Gly Pro Val 
    1430                 1435                 1440             


Met Cys  Leu Thr Val Thr Gln  Thr Ala Ser Gln His  Asp Leu Val 
    1445                 1450                 1455             


Val Thr  Gly Ser Lys Asp His  Tyr Val Lys Met Phe  Glu Leu Gly 
    1460                 1465                 1470             


Glu Cys  Val Thr Gly Thr Ile  Gly Pro Thr His Asn  Phe Glu Pro 
    1475                 1480                 1485             


Pro His  Tyr Asp Gly Ile Glu  Cys Leu Ala Ile Gln  Gly Asp Ile 
    1490                 1495                 1500             


Leu Phe  Ser Gly Ser Arg Asp  Asn Gly Ile Lys Lys  Trp Asp Leu 
    1505                 1510                 1515             


Asp Gln  Gln Glu Leu Ile Gln  Gln Ile Pro Asn Ala  His Lys Asp 
    1520                 1525                 1530             


Trp Val  Cys Ala Leu Ala Phe  Ile Pro Gly Arg Pro  Met Leu Leu 
    1535                 1540                 1545             


Ser Ala  Cys Arg Ala Gly Val  Ile Lys Val Trp Asn  Val Asp Asn 
    1550                 1555                 1560             


Phe Thr  Pro Ile Gly Glu Ile  Lys Gly His Asp Ser  Pro Ile Asn 
    1565                 1570                 1575             


Ala Ile  Cys Thr Asn Ala Lys  His Ile Phe Thr Ala  Ser Ser Asp 
    1580                 1585                 1590             


Cys Arg  Val Lys Leu Trp Asn  Tyr Val Pro Gly Leu  Thr Pro Cys 
    1595                 1600                 1605             


Leu Pro  Arg Arg Val Leu Ala  Ile Lys Gly Arg Ala  Thr Thr Leu 
    1610                 1615                 1620             


Pro 
    


<210>  3910
<211>  217
<212>  PRT
<213>  homo sapiens

<400>  3910

Met Ser Phe Arg Gly Gly Gly Arg Gly Gly Phe Asn Arg Gly Gly Gly 
1               5                   10                  15      


Gly Gly Gly Phe Asn Arg Gly Gly Ser Ser Asn His Phe Arg Gly Gly 
            20                  25                  30          


Gly Gly Gly Gly Gly Gly Gly Asn Phe Arg Gly Gly Gly Arg Gly Gly 
        35                  40                  45              


Phe Gly Arg Gly Gly Gly Arg Gly Gly Phe Asn Lys Gly Gln Asp Gln 
    50                  55                  60                  


Gly Pro Pro Glu Arg Val Val Leu Leu Gly Glu Phe Leu His Pro Cys 
65                  70                  75                  80  


Glu Asp Asp Ile Val Cys Lys Cys Thr Thr Asp Glu Asn Lys Val Pro 
                85                  90                  95      


Tyr Phe Asn Ala Pro Val Tyr Leu Glu Asn Lys Glu Gln Ile Gly Lys 
            100                 105                 110         


Val Asp Glu Ile Phe Gly Gln Leu Arg Asp Phe Tyr Phe Ser Val Lys 
        115                 120                 125             


Leu Ser Glu Asn Met Lys Ala Ser Ser Phe Lys Lys Leu Gln Lys Phe 
    130                 135                 140                 


Tyr Ile Asp Pro Tyr Lys Leu Leu Pro Leu Gln Arg Phe Leu Pro Arg 
145                 150                 155                 160 


Pro Pro Gly Glu Lys Gly Pro Pro Arg Gly Gly Gly Arg Gly Gly Arg 
                165                 170                 175     


Gly Gly Gly Arg Gly Gly Gly Gly Arg Gly Gly Gly Arg Gly Gly Gly 
            180                 185                 190         


Phe Arg Gly Gly Arg Gly Gly Gly Gly Gly Gly Phe Arg Gly Gly Arg 
        195                 200                 205             


Gly Gly Gly Phe Arg Gly Arg Gly His 
    210                 215         


<210>  3911
<211>  140
<212>  PRT
<213>  homo sapiens

<400>  3911

Met Thr Leu Met Met Ser Gly Asp Lys Gly Ile Ser Ala Phe Pro Glu 
1               5                   10                  15      


Ser Asp Asn Leu Phe Lys Trp Val Gly Thr Ile His Gly Ala Ala Gly 
            20                  25                  30          


Thr Val Tyr Glu Asp Leu Arg Tyr Lys Leu Ser Leu Glu Phe Pro Ser 
        35                  40                  45              


Gly Tyr Pro Tyr Asn Ala Pro Thr Val Lys Phe Leu Thr Pro Cys Tyr 
    50                  55                  60                  


His Pro Asn Val Asp Thr Gln Gly Asn Ile Cys Leu Asp Ile Leu Lys 
65                  70                  75                  80  


Glu Lys Trp Ser Ala Leu Tyr Asp Val Arg Thr Ile Leu Leu Ser Ile 
                85                  90                  95      


Gln Ser Leu Leu Gly Glu Pro Asn Ile Asp Ser Pro Leu Asn Thr His 
            100                 105                 110         


Ala Ala Glu Leu Trp Lys Asn Pro Thr Ala Phe Lys Lys Tyr Leu Gln 
        115                 120                 125             


Glu Thr Tyr Ser Lys Gln Val Thr Ser Gln Glu Pro 
    130                 135                 140 


<210>  3912
<211>  152
<212>  PRT
<213>  homo sapiens

<400>  3912

Met Ala Gly Leu Pro Arg Arg Ile Ile Lys Glu Thr Gln Arg Leu Leu 
1               5                   10                  15      


Ala Glu Pro Val Pro Gly Ile Lys Ala Glu Pro Asp Glu Ser Asn Ala 
            20                  25                  30          


Arg Tyr Phe His Val Val Ile Ala Gly Pro Gln Asp Ser Pro Phe Glu 
        35                  40                  45              


Gly Gly Thr Phe Lys Leu Glu Leu Phe Leu Pro Glu Glu Tyr Pro Met 
    50                  55                  60                  


Ala Ala Pro Lys Val Arg Phe Met Thr Lys Ile Tyr His Pro Asn Val 
65                  70                  75                  80  


Asp Lys Leu Gly Arg Ile Cys Leu Asp Ile Leu Lys Asp Lys Trp Ser 
                85                  90                  95      


Pro Ala Leu Gln Ile Arg Thr Val Leu Leu Ser Ile Gln Ala Leu Leu 
            100                 105                 110         


Ser Ala Pro Asn Pro Asp Asp Pro Leu Ala Asn Asp Val Ala Glu Gln 
        115                 120                 125             


Trp Lys Thr Asn Glu Ala Gln Ala Ile Glu Thr Ala Arg Ala Trp Thr 
    130                 135                 140                 


Arg Leu Tyr Ala Met Asn Asn Ile 
145                 150         


<210>  3913
<211>  197
<212>  PRT
<213>  homo sapiens

<400>  3913

Met Gln Arg Ala Ser Arg Leu Lys Arg Glu Leu His Met Leu Ala Thr 
1               5                   10                  15      


Glu Pro Pro Pro Gly Ile Thr Cys Trp Gln Asp Lys Asp Gln Met Asp 
            20                  25                  30          


Asp Leu Arg Ala Gln Ile Leu Gly Gly Ala Asn Thr Pro Tyr Glu Lys 
        35                  40                  45              


Gly Val Phe Lys Leu Glu Val Ile Ile Pro Glu Arg Tyr Pro Phe Glu 
    50                  55                  60                  


Pro Pro Gln Ile Arg Phe Leu Thr Pro Ile Tyr His Pro Asn Ile Asp 
65                  70                  75                  80  


Ser Ala Gly Arg Ile Cys Leu Asp Val Leu Lys Leu Pro Pro Lys Gly 
                85                  90                  95      


Ala Trp Arg Pro Ser Leu Asn Ile Ala Thr Val Leu Thr Ser Ile Gln 
            100                 105                 110         


Leu Leu Met Ser Glu Pro Asn Pro Asp Asp Pro Leu Met Ala Asp Ile 
        115                 120                 125             


Ser Ser Glu Phe Lys Tyr Asn Lys Pro Ala Phe Leu Lys Asn Ala Arg 
    130                 135                 140                 


Gln Trp Thr Glu Lys His Ala Arg Gln Lys Gln Lys Ala Asp Glu Glu 
145                 150                 155                 160 


Glu Met Leu Asp Asn Leu Pro Glu Ala Gly Asp Ser Arg Val His Asn 
                165                 170                 175     


Ser Thr Gln Lys Arg Lys Ala Ser Gln Leu Val Gly Ile Glu Lys Lys 
            180                 185                 190         


Phe His Pro Asp Val 
        195         


<210>  3914
<211>  135
<212>  PRT
<213>  homo sapiens

<400>  3914

Met Met Leu Gln His Pro Gly Gln Val Ser Ala Ser Glu Val Ser Ala 
1               5                   10                  15      


Ser Ala Ile Val Pro Cys Leu Ser Pro Pro Gly Ser Leu Val Phe Glu 
            20                  25                  30          


Asp Phe Ala Asn Leu Thr Pro Phe Val Lys Glu Glu Leu Arg Phe Ala 
        35                  40                  45              


Ile Gln Asn Lys His Leu Cys His Arg Met Ser Ser Ala Leu Glu Ser 
    50                  55                  60                  


Val Thr Val Ser Asp Arg Pro Leu Gly Val Ser Ile Thr Lys Ala Glu 
65                  70                  75                  80  


Val Ala Pro Glu Glu Asp Glu Arg Lys Lys Arg Arg Arg Glu Arg Asn 
                85                  90                  95      


Lys Ile Ala Ala Ala Lys Cys Arg Asn Lys Lys Lys Glu Lys Thr Glu 
            100                 105                 110         


Cys Leu Gln Lys Leu Pro Arg Pro Phe Trp Val Gln Lys Thr Cys Ile 
        115                 120                 125             


Trp Ala Val Asp Ser Cys Lys 
    130                 135 


<210>  3915
<211>  508
<212>  PRT
<213>  homo sapiens

<400>  3915

Met Arg Cys Pro Lys Ser Ala Val Thr Met Arg Asn Glu Glu Leu Leu 
1               5                   10                  15      


Leu Ser Asn Gly Thr Ala Asn Lys Met Asn Gly Ala Leu Asp His Ser 
            20                  25                  30          


Asp Gln Pro Asp Pro Asp Ala Ile Lys Met Phe Val Gly Gln Ile Pro 
        35                  40                  45              


Arg Ser Trp Ser Glu Lys Glu Leu Lys Glu Leu Phe Glu Pro Tyr Gly 
    50                  55                  60                  


Ala Val Tyr Gln Ile Asn Val Leu Arg Asp Arg Ser Gln Asn Pro Pro 
65                  70                  75                  80  


Gln Ser Lys Gly Cys Cys Phe Val Thr Phe Tyr Thr Arg Lys Ala Ala 
                85                  90                  95      


Leu Glu Ala Gln Asn Ala Leu His Asn Ile Lys Thr Leu Pro Gly Met 
            100                 105                 110         


His His Pro Ile Gln Met Lys Pro Ala Asp Ser Glu Lys Ser Asn Ala 
        115                 120                 125             


Val Glu Asp Arg Lys Leu Phe Ile Gly Met Val Ser Lys Lys Cys Asn 
    130                 135                 140                 


Glu Asn Asp Ile Arg Val Met Phe Ser Pro Phe Gly Gln Ile Glu Glu 
145                 150                 155                 160 


Cys Arg Ile Leu Arg Gly Pro Asp Gly Leu Ser Arg Gly Cys Ala Phe 
                165                 170                 175     


Val Thr Phe Ser Thr Arg Ala Met Ala Gln Asn Ala Ile Lys Ala Met 
            180                 185                 190         


His Gln Ser Gln Thr Met Glu Gly Cys Ser Ser Pro Ile Val Val Lys 
        195                 200                 205             


Phe Ala Asp Thr Gln Lys Asp Lys Glu Gln Arg Arg Leu Gln Gln Gln 
    210                 215                 220                 


Leu Ala Gln Gln Met Gln Gln Leu Asn Thr Ala Thr Trp Gly Asn Leu 
225                 230                 235                 240 


Thr Gly Leu Gly Gly Leu Thr Pro Gln Tyr Leu Ala Leu Leu Gln Gln 
                245                 250                 255     


Ala Thr Ser Ser Ser Asn Leu Gly Ala Phe Ser Gly Ile Gln Gln Met 
            260                 265                 270         


Ala Gly Met Asn Ala Leu Gln Leu Gln Asn Leu Ala Thr Leu Ala Ala 
        275                 280                 285             


Ala Ala Ala Ala Ala Gln Thr Ser Ala Thr Ser Thr Asn Ala Asn Pro 
    290                 295                 300                 


Leu Ser Thr Thr Ser Ser Ala Leu Gly Ala Leu Thr Ser Pro Val Ala 
305                 310                 315                 320 


Ala Ser Thr Pro Asn Ser Thr Ala Gly Ala Ala Met Asn Ser Leu Thr 
                325                 330                 335     


Ser Leu Gly Thr Leu Gln Gly Leu Ala Gly Ala Thr Val Gly Leu Asn 
            340                 345                 350         


Asn Ile Asn Ala Leu Ala Gly Met Ala Ala Leu Asn Gly Gly Leu Gly 
        355                 360                 365             


Ala Thr Gly Leu Thr Asn Gly Thr Ala Gly Thr Met Asp Ala Leu Thr 
    370                 375                 380                 


Gln Ala Tyr Ser Gly Ile Gln Gln Tyr Ala Ala Ala Ala Leu Pro Thr 
385                 390                 395                 400 


Leu Tyr Ser Gln Ser Leu Leu Gln Gln Gln Ser Ala Ala Gly Ser Gln 
                405                 410                 415     


Lys Glu Gly Pro Glu Gly Ala Asn Leu Phe Ile Tyr His Leu Pro Gln 
            420                 425                 430         


Glu Phe Gly Asp Gln Asp Ile Leu Gln Met Phe Met Pro Phe Gly Asn 
        435                 440                 445             


Val Ile Ser Ala Lys Val Phe Ile Asp Lys Gln Thr Asn Leu Ser Lys 
    450                 455                 460                 


Cys Phe Gly Phe Val Ser Tyr Asp Asn Pro Val Ser Ala Gln Ala Ala 
465                 470                 475                 480 


Ile Gln Ala Met Asn Gly Phe Gln Ile Gly Met Lys Arg Leu Lys Val 
                485                 490                 495     


Gln Leu Lys Arg Ser Lys Asn Asp Ser Lys Pro Tyr 
            500                 505             


<210>  3916
<211>  295
<212>  PRT
<213>  homo sapiens

<400>  3916

Met Ile Glu Val Leu Thr Thr Thr Asp Ser Gln Lys Leu Leu His Gln 
1               5                   10                  15      


Leu Asn Ala Leu Leu Glu Gln Glu Ser Arg Cys Gln Pro Lys Val Cys 
            20                  25                  30          


Gly Leu Arg Leu Ile Glu Ser Ala His Asp Asn Gly Leu Arg Met Thr 
        35                  40                  45              


Ala Arg Leu Arg Asp Phe Glu Val Lys Asp Leu Leu Ser Leu Thr Gln 
    50                  55                  60                  


Phe Phe Gly Phe Asp Thr Glu Thr Phe Ser Leu Ala Val Asn Leu Leu 
65                  70                  75                  80  


Asp Arg Phe Leu Ser Lys Met Lys Val Gln Pro Lys His Leu Gly Cys 
                85                  90                  95      


Val Gly Leu Ser Cys Phe Tyr Leu Ala Val Lys Ser Ile Glu Glu Glu 
            100                 105                 110         


Arg Asn Val Pro Leu Ala Thr Asp Leu Ile Arg Ile Ser Gln Tyr Arg 
        115                 120                 125             


Phe Thr Val Ser Asp Leu Met Arg Met Glu Lys Ile Val Leu Glu Lys 
    130                 135                 140                 


Val Cys Trp Lys Val Lys Ala Thr Thr Ala Phe Gln Phe Leu Gln Leu 
145                 150                 155                 160 


Tyr Tyr Ser Leu Leu Gln Glu Asn Leu Pro Leu Glu Arg Arg Asn Ser 
                165                 170                 175     


Ile Asn Phe Glu Arg Leu Glu Ala Gln Leu Lys Ala Cys His Cys Arg 
            180                 185                 190         


Ile Ile Phe Ser Lys Ala Lys Pro Ser Val Leu Ala Leu Ser Ile Ile 
        195                 200                 205             


Ala Leu Glu Ile Gln Ala Gln Lys Cys Val Glu Leu Thr Glu Gly Ile 
    210                 215                 220                 


Glu Cys Leu Gln Lys His Ser Lys Ile Asn Gly Arg Asp Leu Thr Phe 
225                 230                 235                 240 


Trp Gln Glu Leu Val Ser Lys Cys Leu Thr Glu Tyr Ser Ser Asn Lys 
                245                 250                 255     


Cys Ser Lys Pro Asn Val Gln Lys Leu Lys Trp Ile Val Ser Gly Arg 
            260                 265                 270         


Thr Ala Arg Gln Leu Lys His Ser Tyr Tyr Arg Ile Thr His Leu Pro 
        275                 280                 285             


Thr Ile Pro Glu Met Val Pro 
    290                 295 


<210>  3917
<211>  65
<212>  PRT
<213>  homo sapiens

<400>  3917

Met Val Arg Thr Lys Ala Asp Ser Val Pro Gly Thr Tyr Arg Lys Val 
1               5                   10                  15      


Val Ala Ala Arg Ala Pro Arg Lys Val Leu Gly Ser Ser Thr Ser Ala 
            20                  25                  30          


Thr Asn Ser Thr Ser Val Ser Ser Arg Lys Glu His Val Leu Cys Asn 
        35                  40                  45              


Leu Ile Thr Gln Met Met Lys Lys Asn Arg Thr Phe Ser Phe Ile Phe 
    50                  55                  60                  


Glu 
65  


<210>  3918
<211>  1586
<212>  PRT
<213>  homo sapiens

<400>  3918

Met Glu Glu Met Arg Asp Ser Tyr Leu Glu Glu Asp Val Tyr Gln Leu 
1               5                   10                  15      


Gln Glu Leu Arg Arg Glu Leu Asp Arg Ala Asn Lys Asn Cys Arg Ile 
            20                  25                  30          


Leu Gln Tyr Arg Leu Arg Lys Ala Glu Gln Lys Ser Leu Lys Val Ala 
        35                  40                  45              


Glu Thr Gly Gln Val Asp Gly Glu Leu Ile Arg Ser Leu Glu Gln Asp 
    50                  55                  60                  


Leu Lys Val Ala Lys Asp Val Ser Val Arg Leu His His Glu Leu Lys 
65                  70                  75                  80  


Thr Val Glu Glu Lys Arg Ala Lys Ala Glu Asp Glu Asn Glu Thr Leu 
                85                  90                  95      


Arg Gln Gln Met Ile Glu Val Glu Ile Ser Lys Gln Ala Leu Gln Asn 
            100                 105                 110         


Glu Leu Glu Arg Leu Lys Glu Ser Ser Leu Lys Arg Arg Ser Thr Arg 
        115                 120                 125             


Glu Met Tyr Lys Glu Lys Lys Thr Phe Asn Gln Asp Asp Ser Ala Asp 
    130                 135                 140                 


Leu Arg Cys Gln Leu Gln Phe Ala Lys Glu Glu Ala Phe Leu Met Arg 
145                 150                 155                 160 


Lys Lys Met Ala Lys Leu Gly Arg Glu Lys Asp Glu Leu Glu Gln Glu 
                165                 170                 175     


Leu Gln Lys Tyr Lys Ser Leu Tyr Gly Asp Val Asp Ser Pro Leu Pro 
            180                 185                 190         


Thr Gly Glu Ala Gly Gly Pro Pro Ser Thr Arg Glu Ala Glu Leu Lys 
        195                 200                 205             


Leu Arg Leu Lys Leu Val Glu Glu Glu Ala Asn Ile Leu Gly Arg Lys 
    210                 215                 220                 


Ile Val Glu Leu Glu Val Glu Asn Arg Gly Leu Lys Ala Glu Met Glu 
225                 230                 235                 240 


Asp Met Arg Gly Gln Gln Glu Arg Glu Gly Pro Gly Arg Asp His Ala 
                245                 250                 255     


Pro Ser Ile Pro Thr Ser Pro Phe Gly Asp Ser Leu Glu Ser Ser Thr 
            260                 265                 270         


Glu Leu Arg Arg His Leu Gln Phe Val Glu Glu Glu Ala Glu Leu Leu 
        275                 280                 285             


Arg Arg Ser Ile Ser Glu Ile Glu Asp His Asn Arg Gln Leu Thr His 
    290                 295                 300                 


Glu Leu Ser Lys Phe Lys Phe Glu Pro Pro Arg Glu Pro Gly Trp Leu 
305                 310                 315                 320 


Gly Glu Gly Ala Ser Pro Gly Ala Gly Gly Gly Ala Pro Leu Gln Glu 
                325                 330                 335     


Glu Leu Lys Ser Ala Arg Leu Gln Ile Ser Glu Leu Ser Gly Lys Val 
            340                 345                 350         


Leu Lys Leu Gln His Glu Asn His Ala Leu Leu Ser Asn Ile Gln Arg 
        355                 360                 365             


Cys Asp Leu Ala Ala His Leu Gly Leu Arg Ala Pro Ser Pro Arg Asp 
    370                 375                 380                 


Ser Asp Ala Glu Ser Asp Ala Gly Lys Lys Glu Ser Asp Gly Glu Glu 
385                 390                 395                 400 


Ser Arg Leu Pro Gln Pro Lys Arg Glu Gly Pro Val Gly Gly Glu Ser 
                405                 410                 415     


Asp Ser Glu Glu Met Phe Glu Lys Thr Ser Gly Phe Gly Ser Gly Lys 
            420                 425                 430         


Pro Ser Glu Ala Ser Glu Pro Cys Pro Thr Glu Leu Leu Lys Ala Arg 
        435                 440                 445             


Glu Asp Ser Glu Tyr Leu Val Thr Leu Lys His Glu Ala Gln Arg Leu 
    450                 455                 460                 


Glu Arg Thr Val Glu Arg Leu Ile Thr Asp Thr Asp Ser Phe Leu His 
465                 470                 475                 480 


Asp Ala Gly Leu Arg Gly Gly Ala Pro Leu Pro Gly Pro Gly Leu Gln 
                485                 490                 495     


Gly Glu Glu Glu Gln Gly Glu Gly Asp Gln Gln Glu Pro Gln Leu Leu 
            500                 505                 510         


Gly Thr Ile Asn Ala Lys Met Lys Ala Phe Lys Lys Glu Leu Gln Ala 
        515                 520                 525             


Phe Leu Glu Gln Val Asn Arg Ile Gly Asp Gly Leu Ser Pro Leu Pro 
    530                 535                 540                 


His Leu Thr Glu Ser Ser Ser Phe Leu Ser Thr Val Thr Ser Val Ser 
545                 550                 555                 560 


Arg Asp Ser Pro Ile Gly Asn Leu Gly Lys Glu Leu Gly Pro Asp Leu 
                565                 570                 575     


Gln Ser Arg Leu Lys Glu Gln Leu Glu Trp Gln Leu Gly Pro Ala Arg 
            580                 585                 590         


Gly Asp Glu Arg Glu Ser Leu Arg Leu Arg Ala Ala Arg Glu Leu His 
        595                 600                 605             


Arg Arg Ala Asp Gly Asp Thr Gly Ser His Gly Leu Gly Gly Gln Thr 
    610                 615                 620                 


Cys Phe Ser Leu Glu Leu Arg Gly Pro Pro Val Leu Pro Glu Gln Ser 
625                 630                 635                 640 


Val Ser Ile Glu Glu Leu Gln Gly Gln Leu Val Gln Ala Ala Arg Leu 
                645                 650                 655     


His Gln Glu Glu Thr Glu Thr Phe Thr Asn Lys Ile His Lys Met Glu 
            660                 665                 670         


Glu Glu His Leu Tyr Ala Leu Arg Trp Lys Glu Leu Glu Met His Ser 
        675                 680                 685             


Leu Ala Leu Gln Asn Thr Leu His Glu Arg Thr Trp Ser Asp Glu Lys 
    690                 695                 700                 


Asn Leu Met Gln Gln Glu Leu Arg Ser Leu Lys Gln Asn Ile Phe Leu 
705                 710                 715                 720 


Phe Tyr Val Lys Leu Arg Trp Leu Leu Lys His Trp Arg Gln Gly Lys 
                725                 730                 735     


Gln Met Glu Glu Glu Gly Glu Glu Phe Thr Glu Gly Glu His Pro Glu 
            740                 745                 750         


Thr Leu Ser Arg Leu Gly Glu Leu Gly Val Gln Gly Gly His Gln Ala 
        755                 760                 765             


Asp Gly Pro Asp His Asp Ser Asp Arg Gly Cys Gly Phe Pro Val Gly 
    770                 775                 780                 


Glu His Ser Pro His Ser Arg Val Gln Ile Gly Asp His Ser Leu Arg 
785                 790                 795                 800 


Leu Gln Thr Ala Asp Arg Gly Gln Pro His Lys Gln Val Val Glu Asn 
                805                 810                 815     


Gln Gln Leu Phe Ser Ala Phe Lys Ala Leu Leu Glu Asp Phe Arg Ala 
            820                 825                 830         


Glu Leu Arg Glu Asp Glu Arg Ala Arg Leu Arg Leu Gln Gln Gln Tyr 
        835                 840                 845             


Ala Ser Asp Lys Ala Ala Trp Asp Val Glu Trp Ala Val Leu Lys Cys 
    850                 855                 860                 


Arg Leu Glu Gln Leu Glu Glu Lys Thr Glu Asn Lys Leu Gly Glu Leu 
865                 870                 875                 880 


Gly Ser Ser Ala Glu Ser Lys Gly Ala Leu Lys Lys Glu Arg Glu Val 
                885                 890                 895     


His Gln Lys Leu Leu Ala Asp Ser His Ser Leu Val Met Asp Leu Arg 
            900                 905                 910         


Trp Gln Ile His His Ser Glu Lys Asn Trp Asn Arg Glu Lys Val Glu 
        915                 920                 925             


Leu Leu Asp Arg Leu Asp Arg Asp Arg Gln Glu Trp Glu Arg Gln Lys 
    930                 935                 940                 


Lys Glu Phe Leu Trp Arg Ile Glu Gln Leu Gln Lys Glu Asn Ser Pro 
945                 950                 955                 960 


Arg Arg Gly Gly Ser Phe Leu Cys Asp Gln Lys Asp Gly Asn Val Arg 
                965                 970                 975     


Pro Phe Pro His Gln Gly Ser Leu Arg Met Pro Arg Pro Val Ala Met 
            980                 985                 990         


Trp Pro Cys Ala Asp Ala Asp Ser  Ile Pro Phe Glu Asp  Arg Pro Leu 
        995                 1000                 1005             


Ser Lys  Leu Lys Glu Ser Asp  Arg Cys Ser Ala Ser  Glu Asn Leu 
    1010                 1015                 1020             


Tyr Leu  Asp Ala Leu Ser Leu  Asp Asp Glu Pro Glu  Glu Pro Pro 
    1025                 1030                 1035             


Ala His  Arg Pro Glu Arg Glu  Phe Arg Asn Arg Leu  Pro Glu Glu 
    1040                 1045                 1050             


Glu Glu  Asn His Lys Gly Asn  Leu Gln Arg Ala Val  Ser Val Ser 
    1055                 1060                 1065             


Ser Met  Ser Glu Phe Gln Arg  Leu Met Asp Ile Ser  Pro Phe Leu 
    1070                 1075                 1080             


Pro Glu  Lys Gly Leu Pro Ser  Thr Ser Ser Lys Glu  Asp Val Thr 
    1085                 1090                 1095             


Pro Pro  Leu Ser Pro Asp Asp  Leu Lys Tyr Ile Glu  Glu Phe Asn 
    1100                 1105                 1110             


Lys Ser  Trp Asp Tyr Thr Pro  Asn Arg Gly His Asn  Gly Gly Gly 
    1115                 1120                 1125             


Pro Asp  Leu Trp Ala Asp Arg  Thr Glu Val Gly Arg  Ala Gly His 
    1130                 1135                 1140             


Glu Asp  Ser Thr Glu Pro Phe  Pro Asp Ser Ser Trp  Tyr Leu Thr 
    1145                 1150                 1155             


Thr Ser  Val Thr Met Thr Thr  Asp Thr Met Thr Ser  Pro Glu His 
    1160                 1165                 1170             


Cys Gln  Lys Gln Pro Leu Arg  Ser His Val Leu Thr  Glu Gln Ser 
    1175                 1180                 1185             


Gly Leu  Arg Val Leu His Ser  Pro Pro Ala Val Arg  Arg Val Asp 
    1190                 1195                 1200             


Ser Ile  Thr Ala Ala Gly Gly  Glu Gly Pro Phe Pro  Thr Ser Arg 
    1205                 1210                 1215             


Ala Arg  Gly Ser Pro Gly Asp  Thr Lys Gly Gly Pro  Pro Glu Pro 
    1220                 1225                 1230             


Met Leu  Ser Arg Trp Pro Cys  Thr Ser Pro Arg His  Ser Arg Asp 
    1235                 1240                 1245             


Tyr Val  Glu Gly Ala Arg Arg  Pro Leu Asp Ser Pro  Leu Cys Thr 
    1250                 1255                 1260             


Ser Leu  Gly Phe Ala Ser Pro  Leu His Ser Leu Glu  Met Ser Lys 
    1265                 1270                 1275             


Asn Leu  Ser Asp Asp Met Lys  Glu Val Ala Phe Ser  Val Arg Asn 
    1280                 1285                 1290             


Ala Ile  Cys Ser Gly Pro Gly  Glu Leu Gln Val Lys  Asp Met Ala 
    1295                 1300                 1305             


Cys Gln  Thr Asn Gly Ser Arg  Thr Met Gly Thr Gln  Thr Val Gln 
    1310                 1315                 1320             


Thr Ile  Ser Val Gly Leu Gln  Thr Glu Ala Leu Arg  Gly Ser Gly 
    1325                 1330                 1335             


Val Thr  Ser Ser Pro His Lys  Cys Leu Thr Pro Lys  Ala Gly Gly 
    1340                 1345                 1350             


Gly Ala  Thr Pro Val Ser Ser  Pro Ser Arg Ser Leu  Arg Ser Arg 
    1355                 1360                 1365             


Gln Val  Ala Pro Ala Ile Glu  Lys Val Gln Ala Lys  Phe Glu Arg 
    1370                 1375                 1380             


Thr Cys  Cys Ser Pro Lys Tyr  Gly Ser Pro Lys Leu  Gln Arg Lys 
    1385                 1390                 1395             


Pro Leu  Pro Lys Ala Asp Gln  Pro Asn Asn Arg Thr  Ser Pro Gly 
    1400                 1405                 1410             


Met Ala  Gln Lys Gly Tyr Ser  Glu Ser Ala Trp Ala  Arg Ser Thr 
    1415                 1420                 1425             


Thr Thr  Arg Glu Ser Pro Val  His Thr Thr Ile Asn  Asp Gly Leu 
    1430                 1435                 1440             


Ser Ser  Leu Phe Asn Ile Ile  Asp His Ser Pro Val  Val Gln Asp 
    1445                 1450                 1455             


Pro Phe  Gln Lys Gly Leu Arg  Ala Gly Ser Arg Ser  Arg Ser Ala 
    1460                 1465                 1470             


Glu Pro  Arg Pro Glu Leu Gly  Pro Gly Gln Glu Thr  Gly Thr Asn 
    1475                 1480                 1485             


Ser Arg  Gly Arg Ser Pro Ser  Pro Ile Gly Val Gly  Ser Glu Met 
    1490                 1495                 1500             


Cys Arg  Glu Glu Gly Gly Glu  Gly Thr Pro Val Lys  Gln Asp Leu 
    1505                 1510                 1515             


Ser Ala  Pro Pro Gly Tyr Thr  Leu Thr Glu Asn Val  Ala Arg Ile 
    1520                 1525                 1530             


Leu Asn  Lys Lys Leu Leu Glu  His Ala Leu Lys Glu  Glu Arg Arg 
    1535                 1540                 1545             


Gln Ala  Ala His Gly Pro Pro  Gly Leu His Ser Asp  Ser His Ser 
    1550                 1555                 1560             


Leu Gly  Asp Thr Ala Glu Pro  Gly Pro Met Glu Asn  Gln Thr Val 
    1565                 1570                 1575             


Leu Leu  Thr Ala Pro Trp Gly  Leu 
    1580                 1585     


<210>  3919
<211>  292
<212>  PRT
<213>  homo sapiens

<400>  3919

Met Pro Ala Ala Leu Val Glu Asn Ser Gln Val Ile Cys Glu Val Trp 
1               5                   10                  15      


Ala Ser Asn Leu Glu Glu Glu Met Arg Lys Ile Arg Glu Ile Val Leu 
            20                  25                  30          


Ser Tyr Ser Tyr Ile Ala Met Asp Thr Glu Phe Pro Gly Val Val Val 
        35                  40                  45              


Arg Pro Ile Gly Glu Phe Arg Ser Ser Ile Asp Tyr Gln Tyr Gln Leu 
    50                  55                  60                  


Leu Arg Cys Asn Val Asp Leu Leu Lys Ile Ile Gln Leu Gly Leu Thr 
65                  70                  75                  80  


Phe Thr Asn Glu Lys Gly Glu Tyr Pro Ser Gly Ile Asn Thr Trp Gln 
                85                  90                  95      


Phe Asn Phe Lys Phe Asn Leu Thr Glu Asp Met Tyr Ser Gln Asp Ser 
            100                 105                 110         


Ile Asp Leu Leu Ala Asn Ser Gly Leu Gln Phe Gln Lys His Glu Glu 
        115                 120                 125             


Glu Gly Ile Asp Thr Leu His Phe Ala Glu Leu Leu Met Thr Ser Gly 
    130                 135                 140                 


Val Val Leu Cys Asp Asn Val Lys Trp Leu Ser Phe His Ser Gly Tyr 
145                 150                 155                 160 


Asp Phe Gly Tyr Met Val Lys Leu Leu Thr Asp Ser Arg Leu Pro Glu 
                165                 170                 175     


Glu Glu His Glu Phe Phe His Ile Leu Asn Leu Phe Phe Pro Ser Ile 
            180                 185                 190         


Tyr Asp Val Lys Tyr Leu Met Lys Ser Cys Lys Asn Leu Lys Gly Gly 
        195                 200                 205             


Leu Gln Glu Val Ala Asp Gln Leu Asp Leu Gln Arg Ile Gly Arg Gln 
    210                 215                 220                 


His Gln Ala Gly Ser Asp Ser Leu Leu Thr Gly Met Ala Phe Phe Arg 
225                 230                 235                 240 


Met Lys Glu Leu Phe Phe Glu Asp Ser Ile Asp Asp Ala Lys Tyr Cys 
                245                 250                 255     


Gly Arg Leu Tyr Gly Leu Gly Thr Gly Val Ala Gln Lys Gln Asn Glu 
            260                 265                 270         


Asp Val Asp Ser Ala Gln Glu Lys Met Ser Ile Leu Ala Ile Ile Asn 
        275                 280                 285             


Asn Met Gln Gln 
    290         


<210>  3920
<211>  111
<212>  PRT
<213>  homo sapiens

<400>  3920

Met Val Arg Thr Lys Ala Asp Ser Val Pro Gly Thr Tyr Arg Lys Val 
1               5                   10                  15      


Val Ala Ala Arg Ala Pro Arg Lys Val Leu Gly Ser Ser Thr Ser Ala 
            20                  25                  30          


Thr Asn Ser Thr Ser Val Ser Ser Arg Lys Ala Glu Asn Lys Tyr Ala 
        35                  40                  45              


Gly Gly Asn Pro Val Cys Val Arg Pro Thr Pro Lys Trp Gln Lys Gly 
    50                  55                  60                  


Ile Gly Glu Phe Phe Arg Leu Ser Pro Lys Asp Ser Glu Lys Glu Asn 
65                  70                  75                  80  


Gln Ile Pro Glu Glu Ala Gly Ser Ser Gly Leu Gly Lys Ala Lys Arg 
                85                  90                  95      


Lys Ala Cys Pro Leu Gln Pro Asp His Thr Asn Asp Glu Lys Glu 
            100                 105                 110     


<210>  3921
<211>  1169
<212>  PRT
<213>  homo sapiens

<400>  3921

Met Ala Arg Gln Pro Pro Pro Pro Trp Val His Ala Ala Phe Leu Leu 
1               5                   10                  15      


Cys Leu Leu Ser Leu Gly Gly Ala Ile Glu Ile Pro Met Asp Leu Thr 
            20                  25                  30          


Gln Pro Pro Thr Ile Thr Lys Gln Ser Ala Lys Asp His Ile Val Asp 
        35                  40                  45              


Pro Arg Asp Asn Ile Leu Ile Glu Cys Glu Ala Lys Gly Asn Pro Ala 
    50                  55                  60                  


Pro Ser Phe His Trp Thr Arg Asn Ser Arg Phe Phe Asn Ile Ala Lys 
65                  70                  75                  80  


Asp Pro Arg Val Ser Met Arg Arg Arg Ser Gly Thr Leu Val Ile Asp 
                85                  90                  95      


Phe Arg Ser Gly Gly Arg Pro Glu Glu Tyr Glu Gly Glu Tyr Gln Cys 
            100                 105                 110         


Phe Ala Arg Asn Lys Phe Gly Thr Ala Leu Ser Asn Arg Ile Arg Leu 
        115                 120                 125             


Gln Val Ser Lys Ser Pro Leu Trp Pro Lys Glu Asn Leu Asp Pro Val 
    130                 135                 140                 


Val Val Gln Glu Gly Ala Pro Leu Thr Leu Gln Cys Asn Pro Pro Pro 
145                 150                 155                 160 


Gly Leu Pro Ser Pro Val Ile Phe Trp Met Ser Ser Ser Met Glu Pro 
                165                 170                 175     


Ile Thr Gln Asp Lys Arg Val Ser Gln Gly His Asn Gly Asp Leu Tyr 
            180                 185                 190         


Phe Ser Asn Val Met Leu Gln Asp Met Gln Thr Asp Tyr Ser Cys Asn 
        195                 200                 205             


Ala Arg Phe His Phe Thr His Thr Ile Gln Gln Lys Asn Pro Phe Thr 
    210                 215                 220                 


Leu Lys Val Leu Thr Asn His Pro Tyr Asn Asp Ser Ser Leu Arg Asn 
225                 230                 235                 240 


His Pro Asp Met Tyr Ser Ala Arg Gly Val Ala Glu Arg Thr Pro Ser 
                245                 250                 255     


Phe Met Tyr Pro Gln Gly Thr Ala Ser Ser Gln Met Val Leu Arg Gly 
            260                 265                 270         


Met Asp Leu Leu Leu Glu Cys Ile Ala Ser Gly Val Pro Thr Pro Asp 
        275                 280                 285             


Ile Ala Trp Tyr Lys Lys Gly Gly Asp Leu Pro Ser Asp Lys Ala Lys 
    290                 295                 300                 


Phe Glu Asn Phe Asn Lys Ala Leu Arg Ile Thr Asn Val Ser Glu Glu 
305                 310                 315                 320 


Asp Ser Gly Glu Tyr Phe Cys Leu Ala Ser Asn Lys Met Gly Ser Ile 
                325                 330                 335     


Arg His Thr Ile Ser Val Arg Val Lys Ala Ala Pro Tyr Trp Leu Asp 
            340                 345                 350         


Glu Pro Lys Asn Leu Ile Leu Ala Pro Gly Glu Asp Gly Arg Leu Val 
        355                 360                 365             


Cys Arg Ala Asn Gly Asn Pro Lys Pro Thr Val Gln Trp Met Val Asn 
    370                 375                 380                 


Gly Glu Pro Leu Gln Ser Ala Pro Pro Asn Pro Asn Arg Glu Val Ala 
385                 390                 395                 400 


Gly Asp Thr Ile Ile Phe Arg Asp Thr Gln Ile Ser Ser Arg Ala Val 
                405                 410                 415     


Tyr Gln Cys Asn Thr Ser Asn Glu His Gly Tyr Leu Leu Ala Asn Ala 
            420                 425                 430         


Phe Val Ser Val Leu Asp Val Pro Pro Arg Met Leu Ser Pro Arg Asn 
        435                 440                 445             


Gln Leu Ile Arg Val Ile Leu Tyr Asn Arg Thr Arg Leu Asp Cys Pro 
    450                 455                 460                 


Phe Phe Gly Ser Pro Ile Pro Thr Leu Arg Trp Phe Lys Asn Gly Gln 
465                 470                 475                 480 


Gly Ser Asn Leu Asp Gly Gly Asn Tyr His Val Tyr Glu Asn Gly Ser 
                485                 490                 495     


Leu Glu Ile Lys Met Ile Arg Lys Glu Asp Gln Gly Ile Tyr Thr Cys 
            500                 505                 510         


Val Ala Thr Asn Ile Leu Gly Lys Ala Glu Asn Gln Val Arg Leu Glu 
        515                 520                 525             


Val Lys Asp Pro Thr Arg Ile Tyr Arg Met Pro Glu Asp Gln Val Ala 
    530                 535                 540                 


Arg Arg Gly Thr Thr Val Gln Leu Glu Cys Arg Val Lys His Asp Pro 
545                 550                 555                 560 


Ser Leu Lys Leu Thr Val Ser Trp Leu Lys Asp Asp Glu Pro Leu Tyr 
                565                 570                 575     


Ile Gly Asn Arg Met Lys Lys Glu Asp Asp Ser Leu Thr Ile Phe Gly 
            580                 585                 590         


Val Ala Glu Arg Asp Gln Gly Ser Tyr Thr Cys Val Ala Ser Thr Glu 
        595                 600                 605             


Leu Asp Gln Asp Leu Ala Lys Ala Tyr Leu Thr Val Leu Gly Arg Pro 
    610                 615                 620                 


Asp Arg Pro Arg Asp Leu Glu Leu Thr Asp Leu Ala Glu Arg Ser Val 
625                 630                 635                 640 


Arg Leu Thr Trp Ile Pro Gly Asp Ala Asn Asn Ser Pro Ile Thr Asp 
                645                 650                 655     


Tyr Val Val Gln Phe Glu Glu Asp Gln Phe Gln Pro Gly Val Trp His 
            660                 665                 670         


Asp His Ser Lys Tyr Pro Gly Ser Val Asn Ser Ala Val Leu Arg Leu 
        675                 680                 685             


Ser Pro Tyr Val Asn Tyr Gln Phe Arg Val Ile Ala Ile Asn Glu Val 
    690                 695                 700                 


Gly Ser Ser His Pro Ser Leu Pro Ser Glu Arg Tyr Arg Thr Ser Gly 
705                 710                 715                 720 


Ala Pro Pro Glu Ser Asn Pro Gly Asp Val Lys Gly Glu Gly Thr Arg 
                725                 730                 735     


Lys Asn Asn Met Glu Ile Thr Trp Thr Pro Met Asn Ala Thr Ser Ala 
            740                 745                 750         


Phe Gly Pro Asn Leu Arg Tyr Ile Val Lys Trp Arg Arg Arg Glu Thr 
        755                 760                 765             


Arg Glu Ala Trp Asn Asn Val Thr Val Trp Gly Ser Arg Tyr Val Val 
    770                 775                 780                 


Gly Gln Thr Pro Val Tyr Val Pro Tyr Glu Ile Arg Val Gln Ala Glu 
785                 790                 795                 800 


Asn Asp Phe Gly Lys Gly Pro Glu Pro Glu Ser Val Ile Gly Tyr Ser 
                805                 810                 815     


Gly Glu Asp Tyr Pro Arg Ala Ala Pro Thr Glu Val Lys Val Arg Val 
            820                 825                 830         


Met Asn Ser Thr Ala Ile Ser Leu Gln Trp Asn Arg Val Tyr Ser Asp 
        835                 840                 845             


Thr Val Gln Gly Gln Leu Arg Glu Tyr Arg Ala Tyr Tyr Trp Arg Glu 
    850                 855                 860                 


Ser Ser Leu Leu Lys Asn Leu Trp Val Ser Gln Lys Arg Gln Gln Ala 
865                 870                 875                 880 


Ser Phe Pro Gly Asp Arg Leu Arg Gly Val Val Ser Arg Leu Phe Pro 
                885                 890                 895     


Tyr Ser Asn Tyr Lys Leu Glu Met Val Val Val Asn Gly Arg Gly Asp 
            900                 905                 910         


Gly Pro Arg Ser Glu Thr Lys Glu Phe Thr Thr Pro Glu Gly Val Pro 
        915                 920                 925             


Ser Ala Pro Arg Arg Phe Arg Val Arg Gln Pro Asn Leu Glu Thr Ile 
    930                 935                 940                 


Asn Leu Glu Trp Asp His Pro Glu His Pro Asn Gly Ile Met Ile Gly 
945                 950                 955                 960 


Tyr Thr Leu Lys Tyr Val Ala Phe Asn Gly Thr Lys Val Gly Lys Gln 
                965                 970                 975     


Ile Val Glu Asn Phe Ser Pro Asn Gln Thr Lys Phe Thr Val Gln Arg 
            980                 985                 990         


Thr Asp Pro Val Ser Arg Tyr Arg  Phe Thr Leu Ser Ala  Arg Thr Gln 
        995                 1000                 1005             


Val Gly  Ser Gly Glu Ala Val  Thr Glu Glu Ser Pro  Ala Pro Pro 
    1010                 1015                 1020             


Asn Glu  Ala Tyr Thr Asn Asn  Gln Ala Asp Ile Ala  Thr Gln Gly 
    1025                 1030                 1035             


Trp Phe  Ile Gly Leu Met Cys  Ala Ile Ala Leu Leu  Val Leu Ile 
    1040                 1045                 1050             


Leu Leu  Ile Val Cys Phe Ile  Lys Arg Ser Arg Gly  Gly Lys Tyr 
    1055                 1060                 1065             


Pro Val  Arg Glu Lys Lys Asp  Val Pro Leu Gly Pro  Glu Asp Pro 
    1070                 1075                 1080             


Lys Glu  Glu Asp Gly Ser Phe  Asp Tyr Ser Asp Glu  Asp Asn Lys 
    1085                 1090                 1095             


Pro Leu  Gln Gly Ser Gln Thr  Ser Leu Asp Gly Thr  Ile Lys Gln 
    1100                 1105                 1110             


Gln Glu  Ser Asp Asp Ser Leu  Val Asp Tyr Gly Glu  Gly Gly Glu 
    1115                 1120                 1125             


Gly Gln  Phe Asn Glu Asp Gly  Ser Phe Ile Gly Gln  Tyr Thr Val 
    1130                 1135                 1140             


Lys Lys  Asp Lys Glu Glu Thr  Glu Gly Asn Glu Ser  Ser Glu Ala 
    1145                 1150                 1155             


Thr Ser  Pro Val Asn Ala Ile  Tyr Ser Leu Ala 
    1160                 1165                 


<210>  3922
<211>  1292
<212>  PRT
<213>  homo sapiens

<400>  3922

Met Ser Ser Glu Cys Asp Gly Gly Ser Lys Ala Val Met Asn Gly Leu 
1               5                   10                  15      


Ala Pro Gly Ser Asn Gly Gln Asp Lys Ala Thr Ala Asp Pro Leu Arg 
            20                  25                  30          


Ala Arg Ser Ile Ser Ala Val Lys Ile Ile Pro Val Lys Thr Val Lys 
        35                  40                  45              


Asn Ala Ser Gly Leu Val Leu Pro Thr Asp Met Asp Pro Thr Lys Ile 
    50                  55                  60                  


Cys Thr Gly Lys Gly Ala Val Thr Leu Arg Ala Ser Ser Ser Tyr Arg 
65                  70                  75                  80  


Glu Thr Pro Ser Ser Ser Pro Ala Ser Pro Gln Glu Thr Arg Gln His 
                85                  90                  95      


Glu Ser Lys Pro Gly Leu Glu Pro Glu Pro Ser Ser Ala Asp Glu Trp 
            100                 105                 110         


Arg Leu Ser Ser Ser Ala Asp Ala Asn Gly Asn Ala Gln Pro Ser Ser 
        115                 120                 125             


Leu Ala Ala Lys Gly Tyr Arg Ser Val His Pro Asn Leu Pro Ser Asp 
    130                 135                 140                 


Lys Ser Gln Asp Ala Thr Ser Ser Ser Ala Ala Gln Pro Glu Val Ile 
145                 150                 155                 160 


Val Val Pro Leu Tyr Leu Val Asn Thr Asp Arg Gly Gln Glu Gly Thr 
                165                 170                 175     


Ala Arg Pro Pro Thr Pro Leu Gly Pro Leu Gly Cys Val Pro Thr Ile 
            180                 185                 190         


Pro Ala Thr Ala Ser Ala Ala Ser Pro Leu Thr Phe Pro Thr Leu Asp 
        195                 200                 205             


Asp Phe Ile Pro Pro His Leu Gln Arg Trp Pro His His Ser Gln Pro 
    210                 215                 220                 


Ala Arg Ala Ser Gly Ser Phe Ala Pro Ile Ser Gln Thr Pro Pro Ser 
225                 230                 235                 240 


Phe Ser Pro Pro Pro Pro Leu Val Pro Pro Ala Pro Glu Asp Leu Arg 
                245                 250                 255     


Arg Val Ser Glu Pro Asp Leu Thr Gly Ala Val Ser Ser Thr Asp Ser 
            260                 265                 270         


Ser Pro Leu Leu Asn Glu Val Ser Ser Ser Leu Ile Gly Thr Asp Ser 
        275                 280                 285             


Gln Ala Phe Pro Ser Val Ser Lys Pro Ser Ser Ala Tyr Pro Ser Thr 
    290                 295                 300                 


Thr Ile Val Asn Pro Thr Ile Val Leu Leu Gln His Asn Arg Glu Gln 
305                 310                 315                 320 


Gln Lys Arg Leu Ser Ser Leu Ser Asp Pro Val Ser Glu Arg Arg Val 
                325                 330                 335     


Gly Glu Gln Asp Ser Ala Pro Thr Gln Glu Lys Pro Thr Ser Pro Gly 
            340                 345                 350         


Lys Ala Ile Glu Lys Arg Ala Lys Asp Asp Ser Arg Arg Val Val Lys 
        355                 360                 365             


Ser Thr Gln Asp Leu Ser Asp Val Ser Met Asp Glu Val Gly Ile Pro 
    370                 375                 380                 


Leu Arg Asn Thr Glu Arg Ser Lys Asp Trp Tyr Lys Thr Met Phe Lys 
385                 390                 395                 400 


Gln Ile His Lys Leu Asn Arg Asp Thr Pro Glu Glu Asn Pro Tyr Phe 
                405                 410                 415     


Pro Thr Tyr Lys Phe Pro Glu Leu Pro Glu Ile Gln Gln Thr Ser Glu 
            420                 425                 430         


Glu Asp Asn Pro Tyr Thr Pro Thr Tyr Gln Phe Pro Ala Ser Thr Pro 
        435                 440                 445             


Ser Pro Lys Ser Glu Asp Asp Asp Ser Asp Leu Tyr Ser Pro Arg Tyr 
    450                 455                 460                 


Ser Phe Ser Glu Asp Thr Lys Ser Pro Leu Ser Val Pro Arg Ser Lys 
465                 470                 475                 480 


Ser Glu Met Ser Tyr Ile Asp Gly Glu Lys Val Val Lys Arg Ser Ala 
                485                 490                 495     


Thr Leu Pro Leu Pro Ala Arg Ser Ser Ser Leu Lys Ser Ser Ser Glu 
            500                 505                 510         


Arg Asn Asp Trp Glu Pro Pro Asp Lys Lys Val Asp Thr Arg Lys Tyr 
        515                 520                 525             


Arg Ala Glu Pro Lys Ser Ile Tyr Glu Tyr Gln Pro Gly Lys Ser Ser 
    530                 535                 540                 


Val Leu Thr Asn Glu Lys Met Ser Arg Asp Ile Ser Pro Glu Glu Ile 
545                 550                 555                 560 


Asp Leu Lys Asn Glu Pro Trp Tyr Lys Phe Phe Ser Glu Leu Glu Phe 
                565                 570                 575     


Gly Lys Pro Pro Pro Lys Lys Ile Trp Asp Tyr Thr Pro Gly Asp Cys 
            580                 585                 590         


Ser Ile Leu Pro Arg Glu Asp Arg Lys Thr Asn Leu Asp Lys Asp Leu 
        595                 600                 605             


Ser Leu Cys Gln Thr Glu Leu Glu Ala Asp Leu Glu Lys Met Glu Thr 
    610                 615                 620                 


Leu Asn Lys Ala Pro Ser Ala Asn Val Pro Gln Ser Ser Ala Ile Ser 
625                 630                 635                 640 


Pro Thr Pro Glu Ile Ser Ser Glu Thr Pro Gly Tyr Ile Tyr Ser Ser 
                645                 650                 655     


Asn Phe His Ala Val Lys Arg Glu Ser Asp Gly Ala Pro Gly Asp Leu 
            660                 665                 670         


Thr Ser Leu Glu Asn Glu Arg Gln Ile Tyr Lys Ser Val Leu Glu Gly 
        675                 680                 685             


Gly Asp Ile Pro Leu Gln Gly Leu Ser Gly Leu Lys Arg Pro Ser Ser 
    690                 695                 700                 


Ser Ala Ser Thr Lys Asp Ser Glu Ser Pro Arg His Phe Ile Pro Ala 
705                 710                 715                 720 


Asp Tyr Leu Glu Ser Thr Glu Glu Phe Ile Arg Arg Arg His Asp Asp 
                725                 730                 735     


Lys Glu Lys Leu Leu Ala Asp Gln Arg Arg Leu Lys Arg Glu Gln Glu 
            740                 745                 750         


Glu Ala Asp Ile Ala Ala Arg Arg His Thr Gly Val Ile Pro Thr His 
        755                 760                 765             


His Gln Phe Ile Thr Asn Glu Arg Phe Gly Asp Leu Leu Asn Ile Asp 
    770                 775                 780                 


Asp Thr Ala Lys Arg Lys Ser Gly Ser Glu Met Arg Pro Ala Arg Ala 
785                 790                 795                 800 


Lys Phe Asp Phe Lys Ala Gln Thr Leu Lys Glu Leu Pro Leu Gln Lys 
                805                 810                 815     


Gly Asp Ile Val Tyr Ile Tyr Lys Gln Ile Asp Gln Asn Trp Tyr Glu 
            820                 825                 830         


Gly Glu His His Gly Arg Val Gly Ile Phe Pro Arg Thr Tyr Ile Glu 
        835                 840                 845             


Leu Leu Pro Pro Ala Glu Lys Ala Gln Pro Lys Lys Leu Thr Pro Val 
    850                 855                 860                 


Gln Val Leu Glu Tyr Gly Glu Ala Ile Ala Lys Phe Asn Phe Asn Gly 
865                 870                 875                 880 


Asp Thr Gln Val Glu Met Ser Phe Arg Lys Gly Glu Arg Ile Thr Leu 
                885                 890                 895     


Leu Arg Gln Val Asp Glu Asn Trp Tyr Glu Gly Arg Ile Pro Gly Thr 
            900                 905                 910         


Ser Arg Gln Gly Ile Phe Pro Ile Thr Tyr Val Asp Val Ile Lys Arg 
        915                 920                 925             


Pro Leu Val Lys Asn Pro Val Asp Tyr Met Asp Leu Pro Phe Ser Ser 
    930                 935                 940                 


Ser Pro Ser Arg Ser Ala Thr Ala Ser Pro Gln Phe Ser Ser His Ser 
945                 950                 955                 960 


Lys Leu Ile Thr Pro Ala Pro Ser Ser Leu Pro His Ser Arg Arg Ala 
                965                 970                 975     


Leu Ser Pro Glu Met His Ala Val Thr Ser Glu Trp Ile Ser Leu Thr 
            980                 985                 990         


Val Gly Val Pro Gly Arg Arg Ser  Leu Ala Leu Thr Pro  Pro Leu Pro 
        995                 1000                 1005             


Pro Leu  Pro Glu Ala Ser Ile  Tyr Asn Thr Asp His  Leu Ala Leu 
    1010                 1015                 1020             


Ser Pro  Arg Ala Ser Pro Ser  Leu Ser Leu Ser Leu  Pro His Leu 
    1025                 1030                 1035             


Ser Trp  Ser Asp Arg Pro Thr  Pro Arg Ser Val Ala  Ser Pro Leu 
    1040                 1045                 1050             


Ala Leu  Pro Ser Pro His Lys  Thr Tyr Ser Leu Ala  Pro Thr Ser 
    1055                 1060                 1065             


Gln Ala  Ser Leu His Met Asn  Gly Asp Gly Gly Val  His Thr Pro 
    1070                 1075                 1080             


Ser Ser  Gly Ile His Gln Asp  Ser Phe Leu Gln Leu  Pro Leu Gly 
    1085                 1090                 1095             


Ser Ser  Asp Ser Val Ile Ser  Gln Leu Ser Asp Ala  Phe Ser Ser 
    1100                 1105                 1110             


Gln Ser  Lys Arg Gln Pro Trp  Arg Glu Glu Ser Gly  Gln Tyr Glu 
    1115                 1120                 1125             


Arg Lys  Ala Glu Arg Gly Ala  Gly Glu Arg Gly Pro  Gly Gly Pro 
    1130                 1135                 1140             


Lys Ile  Ser Lys Lys Ser Cys  Leu Lys Pro Ser Asp  Val Val Arg 
    1145                 1150                 1155             


Cys Leu  Ser Thr Glu Gln Arg  Leu Ser Asp Leu Asn  Thr Pro Glu 
    1160                 1165                 1170             


Glu Ser  Arg Pro Gly Lys Pro  Leu Gly Ser Ala Phe  Pro Gly Ser 
    1175                 1180                 1185             


Glu Ala  Glu Gln Thr Glu Arg  His Arg Gly Gly Glu  Gln Ala Gly 
    1190                 1195                 1200             


Arg Lys  Ala Ala Arg Arg Gly  Gly Ser Gln Gln Pro  Gln Ala Gln 
    1205                 1210                 1215             


Gln Arg  Arg Val Thr Pro Asp  Arg Ser Gln Thr Ser  Gln Asp Leu 
    1220                 1225                 1230             


Phe Ser  Tyr Gln Ala Leu Tyr  Ser Tyr Ile Pro Gln  Asn Asp Asp 
    1235                 1240                 1245             


Glu Leu  Glu Leu Arg Asp Gly  Asp Ile Val Asp Val  Met Glu Lys 
    1250                 1255                 1260             


Cys Asp  Asp Gly Trp Phe Val  Gly Thr Ser Arg Arg  Thr Lys Gln 
    1265                 1270                 1275             


Phe Gly  Thr Phe Pro Gly Asn  Tyr Val Lys Pro Leu  Tyr Leu 
    1280                 1285                 1290         


<210>  3923
<211>  351
<212>  PRT
<213>  homo sapiens

<400>  3923

Met Thr Glu Met Ser Phe Leu Ser Ser Glu Val Leu Val Gly Asp Leu 
1               5                   10                  15      


Met Ser Pro Phe Asp Gln Ser Gly Leu Gly Ala Glu Glu Ser Leu Gly 
            20                  25                  30          


Leu Leu Asp Asp Tyr Leu Glu Val Ala Lys His Phe Lys Pro His Gly 
        35                  40                  45              


Phe Ser Ser Asp Lys Ala Lys Ala Gly Ser Ser Glu Trp Leu Ala Val 
    50                  55                  60                  


Asp Gly Leu Val Ser Pro Ser Asn Asn Ser Lys Glu Asp Ala Phe Ser 
65                  70                  75                  80  


Gly Thr Asp Trp Met Leu Glu Lys Met Asp Leu Lys Glu Phe Asp Leu 
                85                  90                  95      


Asp Ala Leu Leu Gly Ile Asp Asp Leu Glu Thr Met Pro Asp Asp Leu 
            100                 105                 110         


Leu Thr Thr Leu Asp Asp Thr Cys Asp Leu Phe Ala Pro Leu Val Gln 
        115                 120                 125             


Glu Thr Asn Lys Gln Pro Pro Gln Thr Val Asn Pro Ile Gly His Leu 
    130                 135                 140                 


Pro Glu Ser Leu Thr Lys Pro Asp Gln Val Ala Pro Phe Thr Phe Leu 
145                 150                 155                 160 


Gln Pro Leu Pro Leu Ser Pro Gly Val Leu Ser Ser Thr Pro Asp His 
                165                 170                 175     


Ser Phe Ser Leu Glu Leu Gly Ser Glu Val Asp Ile Thr Glu Gly Asp 
            180                 185                 190         


Arg Lys Pro Asp Tyr Thr Ala Tyr Val Ala Met Ile Pro Gln Cys Ile 
        195                 200                 205             


Lys Glu Glu Asp Thr Pro Ser Asp Asn Asp Ser Gly Ile Cys Met Ser 
    210                 215                 220                 


Pro Glu Ser Tyr Leu Gly Ser Pro Gln His Ser Pro Ser Thr Arg Gly 
225                 230                 235                 240 


Ser Pro Asn Arg Ser Leu Pro Ser Pro Gly Val Leu Cys Gly Ser Ala 
                245                 250                 255     


Arg Pro Lys Pro Tyr Asp Pro Pro Gly Glu Lys Met Val Ala Ala Lys 
            260                 265                 270         


Val Lys Gly Glu Lys Leu Asp Lys Lys Leu Lys Lys Met Glu Gln Asn 
        275                 280                 285             


Lys Thr Ala Ala Thr Arg Tyr Arg Gln Lys Lys Arg Ala Glu Gln Glu 
    290                 295                 300                 


Ala Leu Thr Gly Glu Cys Lys Glu Leu Glu Lys Lys Asn Glu Ala Leu 
305                 310                 315                 320 


Lys Glu Arg Ala Asp Ser Leu Ala Lys Glu Ile Gln Tyr Leu Lys Asp 
                325                 330                 335     


Leu Ile Glu Glu Val Arg Lys Ala Arg Gly Lys Lys Arg Val Pro 
            340                 345                 350     


<210>  3924
<211>  1068
<212>  PRT
<213>  homo sapiens

<400>  3924

Met Leu Val Gly Ser Gln Ser Phe Ser Pro Gly Gly Pro Asn Gly Ile 
1               5                   10                  15      


Ile Arg Ser Gln Ser Phe Ala Gly Phe Ser Gly Leu Gln Glu Arg Arg 
            20                  25                  30          


Ser Arg Cys Asn Ser Phe Ile Glu Asn Ser Ser Ala Leu Lys Lys Pro 
        35                  40                  45              


Gln Ala Lys Leu Lys Lys Met His Asn Leu Gly His Lys Asn Asn Asn 
    50                  55                  60                  


Pro Pro Lys Glu Pro Gln Pro Lys Arg Val Glu Glu Val Tyr Arg Ala 
65                  70                  75                  80  


Leu Lys Asn Gly Leu Asp Glu Tyr Leu Glu Val His Gln Thr Glu Leu 
                85                  90                  95      


Asp Lys Leu Thr Ala Gln Leu Lys Asp Met Lys Arg Asn Ser Arg Leu 
            100                 105                 110         


Gly Val Leu Tyr Asp Leu Asp Lys Gln Ile Lys Thr Ile Glu Arg Tyr 
        115                 120                 125             


Met Arg Arg Leu Glu Phe His Ile Ser Lys Val Asp Glu Leu Tyr Glu 
    130                 135                 140                 


Ala Tyr Cys Ile Gln Arg Arg Leu Gln Asp Gly Ala Ser Lys Met Lys 
145                 150                 155                 160 


Gln Ala Phe Ala Thr Ser Pro Ala Ser Lys Ala Ala Arg Glu Ser Leu 
                165                 170                 175     


Thr Glu Ile Asn Arg Ser Phe Lys Glu Tyr Thr Glu Asn Met Cys Thr 
            180                 185                 190         


Ile Glu Val Glu Leu Glu Asn Leu Leu Gly Glu Phe Ser Ile Lys Met 
        195                 200                 205             


Lys Gly Leu Ala Gly Phe Ala Arg Leu Cys Pro Gly Asp Gln Tyr Glu 
    210                 215                 220                 


Ile Phe Met Lys Tyr Gly Arg Gln Arg Trp Lys Leu Lys Gly Lys Ile 
225                 230                 235                 240 


Glu Val Asn Gly Lys Gln Ser Trp Asp Gly Glu Glu Thr Val Phe Leu 
                245                 250                 255     


Pro Leu Ile Val Gly Phe Ile Ser Ile Lys Val Thr Glu Leu Lys Gly 
            260                 265                 270         


Leu Ala Thr His Ile Leu Val Gly Ser Val Thr Cys Glu Thr Lys Glu 
        275                 280                 285             


Leu Phe Ala Ala Arg Pro Gln Val Val Ala Val Asp Ile Asn Asp Leu 
    290                 295                 300                 


Gly Thr Ile Lys Leu Asn Leu Glu Ile Thr Trp Tyr Pro Phe Asp Val 
305                 310                 315                 320 


Glu Asp Met Thr Ala Ser Ser Gly Ala Gly Asn Lys Ala Ala Ala Leu 
                325                 330                 335     


Gln Arg Arg Met Ser Met Tyr Ser Gln Gly Thr Pro Glu Thr Pro Thr 
            340                 345                 350         


Phe Lys Asp His Ser Phe Phe Arg Trp Leu His Pro Ser Pro Asp Lys 
        355                 360                 365             


Pro Arg Arg Leu Ser Val Leu Ser Ala Leu Gln Asp Thr Phe Phe Ala 
    370                 375                 380                 


Lys Leu His Arg Ser Arg Ser Phe Ser Asp Leu Pro Ser Leu Arg Pro 
385                 390                 395                 400 


Ser Pro Lys Ala Val Leu Glu Leu Tyr Ser Asn Leu Pro Asp Asp Ile 
                405                 410                 415     


Phe Glu Asn Gly Lys Ala Ala Glu Glu Lys Met Pro Leu Ser Leu Ser 
            420                 425                 430         


Phe Ser Asp Leu Pro Asn Gly Asp Cys Ala Leu Thr Ser His Ser Thr 
        435                 440                 445             


Gly Ser Pro Ser Asn Ser Thr Asn Pro Glu Ile Thr Ile Thr Pro Ala 
    450                 455                 460                 


Glu Phe Asn Leu Ser Ser Leu Ala Ser Gln Asn Glu Gly Met Asp Asp 
465                 470                 475                 480 


Thr Ser Ser Ala Ser Ser Arg Asn Ser Leu Gly Glu Gly Gln Glu Pro 
                485                 490                 495     


Lys Ser His Leu Lys Glu Glu Asp Pro Glu Glu Pro Arg Lys Pro Ala 
            500                 505                 510         


Ser Ala Pro Ser Glu Ala Cys Arg Arg Gln Ser Ser Gly Ala Gly Ala 
        515                 520                 525             


Glu His Leu Phe Leu Glu Asn Asp Val Ala Glu Ala Leu Leu Gln Glu 
    530                 535                 540                 


Ser Glu Glu Ala Ser Glu Leu Lys Pro Val Glu Leu Asp Thr Ser Glu 
545                 550                 555                 560 


Gly Asn Ile Thr Lys Gln Leu Val Lys Arg Leu Thr Ser Ala Glu Val 
                565                 570                 575     


Pro Met Ala Thr Asp Arg Leu Leu Ser Glu Gly Ser Val Gly Gly Glu 
            580                 585                 590         


Ser Glu Gly Cys Arg Ser Phe Leu Asp Gly Ser Leu Glu Asp Ala Phe 
        595                 600                 605             


Asn Gly Leu Leu Leu Ala Leu Glu Pro His Lys Glu Gln Tyr Lys Glu 
    610                 615                 620                 


Phe Gln Asp Leu Asn Gln Glu Val Met Asn Leu Asp Asp Ile Leu Lys 
625                 630                 635                 640 


Cys Lys Pro Ala Val Ser Arg Ser Arg Ser Ser Ser Leu Ser Leu Thr 
                645                 650                 655     


Val Glu Ser Ala Leu Glu Ser Phe Asp Phe Leu Asn Thr Ser Asp Phe 
            660                 665                 670         


Asp Glu Glu Glu Asp Gly Asp Glu Val Cys Asn Val Gly Gly Gly Ala 
        675                 680                 685             


Asp Ser Val Phe Ser Asp Thr Glu Thr Glu Lys His Ser Tyr Arg Ser 
    690                 695                 700                 


Val His Pro Glu Ala Arg Gly His Leu Ser Glu Ala Leu Thr Glu Asp 
705                 710                 715                 720 


Thr Gly Val Gly Thr Ser Val Ala Gly Ser Pro Leu Pro Leu Thr Thr 
                725                 730                 735     


Gly Asn Glu Ser Leu Asp Ile Thr Ile Val Arg His Leu Gln Tyr Cys 
            740                 745                 750         


Thr Gln Leu Val Gln Gln Ile Val Phe Ser Ser Lys Thr Pro Phe Val 
        755                 760                 765             


Ala Arg Ser Leu Leu Glu Lys Leu Ser Arg Gln Ile Gln Val Met Glu 
    770                 775                 780                 


Lys Leu Ala Ala Val Ser Asp Glu Asn Ile Gly Asn Ile Ser Ser Val 
785                 790                 795                 800 


Val Glu Ala Ile Pro Glu Phe His Lys Lys Leu Ser Leu Leu Ser Phe 
                805                 810                 815     


Trp Thr Lys Cys Cys Ser Pro Val Gly Val Tyr His Ser Pro Ala Asp 
            820                 825                 830         


Arg Val Met Lys Gln Leu Glu Ala Ser Phe Ala Arg Thr Val Asn Lys 
        835                 840                 845             


Glu Tyr Pro Gly Leu Ala Asp Pro Val Phe Arg Thr Leu Val Ser Gln 
    850                 855                 860                 


Ile Leu Asp Arg Ala Glu Pro Leu Leu Ser Ser Ser Leu Ser Ser Glu 
865                 870                 875                 880 


Val Val Thr Val Phe Gln Tyr Tyr Ser Tyr Phe Thr Ser His Gly Val 
                885                 890                 895     


Ser Asp Leu Glu Ser Tyr Leu Ser Gln Leu Ala Arg Gln Val Ser Met 
            900                 905                 910         


Val Gln Thr Leu Gln Ser Leu Arg Asp Glu Lys Leu Leu Gln Thr Met 
        915                 920                 925             


Ser Asp Leu Ala Pro Ser Asn Leu Leu Ala Gln Gln Glu Val Leu Arg 
    930                 935                 940                 


Thr Leu Ala Leu Leu Leu Thr Arg Glu Asp Asn Glu Val Ser Glu Ala 
945                 950                 955                 960 


Val Thr Leu Tyr Leu Ala Ala Ala Ser Lys Asn Gln His Phe Arg Glu 
                965                 970                 975     


Lys Ala Leu Leu Tyr Tyr Cys Glu Ala Leu Thr Lys Thr Asn Leu Gln 
            980                 985                 990         


Leu Gln Lys Ala Ala Cys Leu Ala  Leu Lys Ile Leu Glu  Ala Thr Glu 
        995                 1000                 1005             


Ser Ile  Lys Met Leu Val Thr  Leu Cys Gln Ser Asp  Thr Glu Glu 
    1010                 1015                 1020             


Ile Arg  Asn Val Ala Ser Glu  Thr Leu Leu Ser Leu  Gly Glu Asp 
    1025                 1030                 1035             


Gly Arg  Leu Ala Tyr Glu Gln  Leu Asp Lys Phe Pro  Arg Asp Cys 
    1040                 1045                 1050             


Val Lys  Val Gly Gly Arg His  Gly Thr Glu Val Ala  Thr Ala Phe 
    1055                 1060                 1065             


<210>  3925
<211>  615
<212>  PRT
<213>  homo sapiens

<400>  3925

Met Ala Arg Ala Cys Leu Ile Gln Arg Leu Pro Ile Lys Arg Asp Cys 
1               5                   10                  15      


Thr Pro Val Phe Val Arg Gly Leu Ser Ser Pro Ser Ala Ala Met Ala 
            20                  25                  30          


Leu Leu Ser Glu Gly Leu Asp Glu Val Pro Ala Ala Cys Leu Ser Pro 
        35                  40                  45              


Cys Gly Pro Pro Asn Pro Thr Glu Leu Phe Ser Glu Ser Arg Arg Leu 
    50                  55                  60                  


Ala Leu Glu Glu Leu Val Ala Gly Gly Pro Glu Ala Phe Ala Ala Phe 
65                  70                  75                  80  


Leu Arg Arg Glu Arg Leu Ala Arg Phe Leu Asn Pro Asp Glu Val His 
                85                  90                  95      


Ala Ile Leu Arg Ala Ala Glu Arg Pro Gly Glu Glu Gly Ala Ala Ala 
            100                 105                 110         


Ala Ala Ala Ala Glu Asp Ser Phe Gly Ser Ser His Asp Cys Ser Ser 
        115                 120                 125             


Gly Thr Tyr Phe Pro Glu Gln Ser Asp Leu Glu Pro Pro Leu Leu Glu 
    130                 135                 140                 


Leu Gly Trp Pro Ala Phe Tyr Gln Gly Ala Tyr Arg Gly Ala Thr Arg 
145                 150                 155                 160 


Val Glu Thr His Phe Gln Pro Arg Gly Ala Gly Glu Gly Gly Pro Tyr 
                165                 170                 175     


Gly Cys Lys Asp Ala Leu Arg Gln Gln Leu Arg Ser Ala Arg Glu Val 
            180                 185                 190         


Ile Ala Val Val Met Asp Val Phe Thr Asp Ile Asp Ile Phe Arg Asp 
        195                 200                 205             


Leu Gln Glu Ile Cys Arg Lys Gln Gly Val Ala Val Tyr Ile Leu Leu 
    210                 215                 220                 


Asp Gln Ala Leu Leu Ser Gln Phe Leu Asp Met Cys Met Asp Leu Lys 
225                 230                 235                 240 


Val His Pro Glu Gln Glu Lys Leu Met Thr Val Arg Thr Ile Thr Gly 
                245                 250                 255     


Asn Ile Tyr Tyr Ala Arg Ser Gly Thr Lys Ile Ile Gly Lys Val His 
            260                 265                 270         


Glu Lys Phe Thr Leu Ile Asp Gly Ile Arg Val Ala Thr Gly Ser Tyr 
        275                 280                 285             


Ser Phe Thr Trp Thr Asp Gly Lys Leu Asn Ser Ser Asn Leu Val Ile 
    290                 295                 300                 


Leu Ser Gly Gln Val Val Glu His Phe Asp Leu Glu Phe Arg Ile Leu 
305                 310                 315                 320 


Tyr Ala Gln Ser Lys Pro Ile Ser Pro Lys Leu Leu Ser His Phe Gln 
                325                 330                 335     


Ser Ser Asn Lys Phe Asp His Leu Thr Asn Arg Lys Pro Gln Ser Lys 
            340                 345                 350         


Glu Leu Thr Leu Gly Asn Leu Leu Arg Met Arg Leu Ala Arg Leu Ser 
        355                 360                 365             


Ser Thr Pro Arg Lys Ala Asp Leu Asp Pro Glu Met Pro Ala Glu Gly 
    370                 375                 380                 


Lys Ala Glu Arg Lys Pro His Asp Cys Glu Ser Ser Thr Val Ser Glu 
385                 390                 395                 400 


Glu Asp Tyr Phe Ser Ser His Arg Asp Glu Leu Gln Ser Arg Lys Ala 
                405                 410                 415     


Ile Asp Ala Ala Thr Gln Thr Glu Pro Gly Glu Glu Met Pro Gly Leu 
            420                 425                 430         


Ser Val Ser Glu Val Gly Thr Gln Thr Ser Ile Thr Thr Ala Cys Ala 
        435                 440                 445             


Gly Thr Gln Thr Ala Val Ile Thr Arg Ile Ala Ser Ser Gln Thr Thr 
    450                 455                 460                 


Ile Trp Ser Arg Ser Thr Thr Thr Gln Thr Asp Met Asp Glu Asn Ile 
465                 470                 475                 480 


Leu Phe Pro Arg Gly Thr Gln Ser Thr Glu Gly Ser Pro Val Ser Lys 
                485                 490                 495     


Met Ser Val Ser Arg Ser Ser Ser Leu Lys Ser Ser Ser Ser Val Ser 
            500                 505                 510         


Ser Gln Gly Ser Val Ala Ser Ser Thr Gly Ser Pro Ala Ser Ile Arg 
        515                 520                 525             


Thr Thr Asp Phe His Asn Pro Gly Tyr Pro Lys Tyr Leu Gly Thr Pro 
    530                 535                 540                 


His Leu Glu Leu Tyr Leu Ser Asp Ser Leu Arg Asn Leu Asn Lys Glu 
545                 550                 555                 560 


Arg Gln Phe His Phe Ala Gly Ile Arg Ser Arg Leu Asn His Met Leu 
                565                 570                 575     


Ala Met Leu Ser Arg Arg Thr Leu Phe Thr Glu Asn His Leu Gly Leu 
            580                 585                 590         


His Ser Gly Asn Phe Ser Arg Val Asn Leu Leu Ala Val Arg Asp Val 
        595                 600                 605             


Ala Leu Tyr Pro Ser Tyr Gln 
    610                 615 


<210>  3926
<211>  160
<212>  PRT
<213>  homo sapiens

<400>  3926

Met Gln Arg Val Ser Gly Leu Leu Ser Trp Thr Leu Ser Arg Val Leu 
1               5                   10                  15      


Trp Leu Ser Gly Leu Ser Glu Pro Gly Ala Ala Arg Gln Pro Arg Ile 
            20                  25                  30          


Met Glu Glu Lys Ala Leu Glu Val Tyr Asp Leu Ile Arg Thr Ile Arg 
        35                  40                  45              


Asp Pro Glu Lys Pro Asn Thr Leu Glu Glu Leu Glu Val Val Ser Glu 
    50                  55                  60                  


Ser Cys Val Glu Val Gln Glu Ile Asn Glu Glu Glu Tyr Leu Val Ile 
65                  70                  75                  80  


Ile Arg Phe Thr Pro Thr Val Pro His Cys Ser Leu Ala Thr Leu Ile 
                85                  90                  95      


Gly Leu Cys Leu Arg Val Lys Leu Gln Arg Cys Leu Pro Phe Lys His 
            100                 105                 110         


Lys Leu Glu Ile Tyr Ile Ser Glu Gly Thr His Ser Thr Glu Glu Asp 
        115                 120                 125             


Ile Asn Lys Gln Ile Asn Asp Lys Glu Arg Val Ala Ala Ala Met Glu 
    130                 135                 140                 


Asn Pro Asn Leu Arg Glu Ile Val Glu Gln Cys Val Leu Glu Pro Asp 
145                 150                 155                 160 


<210>  3927
<211>  1162
<212>  PRT
<213>  homo sapiens

<400>  3927

Met Ala His Ala Gly Gly Gly Ser Gly Gly Ser Gly Ala Gly Gly Pro 
1               5                   10                  15      


Ala Gly Arg Gly Leu Ser Gly Ala Arg Trp Gly Arg Ser Gly Ser Ala 
            20                  25                  30          


Gly His Glu Lys Leu Pro Val His Val Glu Asp Ala Leu Thr Tyr Leu 
        35                  40                  45              


Asp Gln Val Lys Ile Arg Phe Gly Ser Asp Pro Ala Thr Tyr Asn Gly 
    50                  55                  60                  


Phe Leu Glu Ile Met Lys Glu Phe Lys Ser Gln Ser Ile Asp Thr Pro 
65                  70                  75                  80  


Gly Val Ile Arg Arg Val Ser Gln Leu Phe His Glu His Pro Asp Leu 
                85                  90                  95      


Ile Val Gly Phe Asn Ala Phe Leu Pro Leu Gly Tyr Arg Ile Asp Ile 
            100                 105                 110         


Pro Lys Asn Gly Lys Leu Asn Ile Gln Ser Pro Leu Thr Ser Gln Glu 
        115                 120                 125             


Asn Ser His Asn His Gly Asp Gly Ala Glu Asp Phe Lys Gln Gln Val 
    130                 135                 140                 


Pro Tyr Lys Glu Asp Lys Pro Gln Val Pro Leu Glu Ser Asp Ser Val 
145                 150                 155                 160 


Glu Phe Asn Asn Ala Ile Ser Tyr Val Asn Lys Ile Lys Thr Arg Phe 
                165                 170                 175     


Leu Asp His Pro Glu Ile Tyr Arg Ser Phe Leu Glu Ile Leu His Thr 
            180                 185                 190         


Tyr Gln Lys Glu Gln Leu Asn Thr Arg Gly Arg Pro Phe Arg Gly Met 
        195                 200                 205             


Ser Glu Glu Glu Val Phe Thr Glu Val Ala Asn Leu Phe Arg Gly Gln 
    210                 215                 220                 


Glu Asp Leu Leu Ser Glu Phe Gly Gln Phe Leu Pro Glu Ala Lys Arg 
225                 230                 235                 240 


Ser Leu Phe Thr Gly Asn Gly Pro Cys Glu Met His Ser Val Gln Lys 
                245                 250                 255     


Asn Glu His Asp Lys Thr Pro Glu His Ser Arg Lys Arg Ser Arg Pro 
            260                 265                 270         


Ser Leu Leu Arg Pro Val Ser Ala Pro Ala Lys Lys Lys Met Lys Leu 
        275                 280                 285             


Arg Gly Thr Lys Asp Leu Ser Ile Ala Ala Val Gly Lys Tyr Gly Thr 
    290                 295                 300                 


Leu Gln Glu Phe Ser Phe Phe Asp Lys Val Arg Arg Val Leu Lys Ser 
305                 310                 315                 320 


Gln Glu Val Tyr Glu Asn Phe Leu Arg Cys Ile Ala Leu Phe Asn Gln 
                325                 330                 335     


Glu Leu Val Ser Gly Ser Glu Leu Leu Gln Leu Val Ser Pro Phe Leu 
            340                 345                 350         


Gly Lys Phe Pro Glu Leu Phe Ala Gln Phe Lys Ser Phe Leu Gly Val 
        355                 360                 365             


Lys Glu Leu Ser Phe Ala Pro Pro Met Ser Asp Arg Ser Gly Asp Gly 
    370                 375                 380                 


Ile Ser Arg Glu Ile Asp Tyr Ala Ser Cys Lys Arg Ile Gly Ser Ser 
385                 390                 395                 400 


Tyr Arg Ala Leu Pro Lys Thr Tyr Gln Gln Pro Lys Cys Ser Gly Arg 
                405                 410                 415     


Thr Ala Ile Cys Lys Glu Leu Asp His Trp Thr Leu Leu Gln Gly Ser 
            420                 425                 430         


Trp Thr Asp Asp Tyr Cys Met Ser Lys Phe Lys Asn Thr Cys Trp Ile 
        435                 440                 445             


Pro Gly Tyr Ser Ala Gly Val Leu Asn Asp Thr Trp Val Ser Phe Pro 
    450                 455                 460                 


Ser Trp Ser Glu Asp Ser Thr Phe Val Ser Ser Lys Lys Thr Pro Tyr 
465                 470                 475                 480 


Glu Glu Gln Leu His Arg Cys Glu Asp Glu Arg Phe Glu Leu Asp Val 
                485                 490                 495     


Val Leu Glu Thr Asn Leu Ala Thr Ile Arg Val Leu Glu Ser Val Gln 
            500                 505                 510         


Lys Lys Leu Ser Arg Met Ala Pro Glu Asp Gln Glu Lys Phe Arg Leu 
        515                 520                 525             


Asp Asp Ser Leu Gly Gly Thr Ser Glu Val Ile Gln Arg Arg Ala Ile 
    530                 535                 540                 


Tyr Arg Ile Tyr Gly Asp Lys Ala Pro Glu Ile Ile Glu Ser Leu Lys 
545                 550                 555                 560 


Lys Asn Pro Val Thr Ala Val Pro Val Val Leu Lys Arg Leu Lys Ala 
                565                 570                 575     


Lys Glu Glu Glu Trp Arg Glu Ala Gln Gln Gly Phe Asn Lys Ile Trp 
            580                 585                 590         


Arg Glu Gln Tyr Glu Lys Ala Tyr Leu Lys Ser Leu Asp His Gln Ala 
        595                 600                 605             


Val Asn Phe Lys Gln Asn Asp Thr Lys Ala Leu Arg Ser Lys Ser Leu 
    610                 615                 620                 


Leu Asn Glu Ile Glu Ser Val Tyr Asp Glu His Gln Glu Gln His Ser 
625                 630                 635                 640 


Glu Gly Arg Ser Ala Pro Ser Ser Glu Pro His Leu Ile Phe Val Tyr 
                645                 650                 655     


Glu Asp Arg Gln Ile Leu Glu Asp Ala Ala Ala Leu Ile Ser Tyr Tyr 
            660                 665                 670         


Val Lys Arg Gln Pro Ala Ile Gln Lys Glu Asp Gln Gly Thr Ile His 
        675                 680                 685             


Gln Leu Leu His Gln Phe Val Pro Ser Leu Phe Phe Ser Gln Gln Leu 
    690                 695                 700                 


Asp Leu Gly Ala Ser Glu Glu Ser Ala Asp Glu Asp Arg Asp Ser Pro 
705                 710                 715                 720 


Gln Gly Gln Thr Thr Asp Pro Ser Glu Arg Lys Lys Pro Ala Pro Gly 
                725                 730                 735     


Pro His Ser Ser Pro Pro Glu Glu Lys Gly Ala Phe Gly Asp Ala Pro 
            740                 745                 750         


Ala Thr Glu Gln Pro Pro Leu Pro Pro Pro Ala Pro His Lys Pro Leu 
        755                 760                 765             


Asp Asp Val Tyr Ser Leu Phe Phe Ala Asn Asn Asn Trp Tyr Phe Phe 
    770                 775                 780                 


Leu Arg Leu His Gln Thr Leu Cys Ser Arg Leu Leu Lys Ile Tyr Arg 
785                 790                 795                 800 


Gln Ala Gln Lys Gln Leu Leu Glu Tyr Arg Thr Glu Lys Glu Arg Glu 
                805                 810                 815     


Lys Leu Leu Cys Glu Gly Arg Arg Glu Lys Gly Ser Asp Pro Ala Met 
            820                 825                 830         


Glu Leu Arg Leu Lys Gln Pro Ser Glu Val Glu Leu Glu Glu Tyr Tyr 
        835                 840                 845             


Pro Ala Phe Leu Asp Met Val Arg Ser Leu Leu Glu Gly Ser Ile Asp 
    850                 855                 860                 


Pro Thr Gln Tyr Glu Asp Thr Leu Arg Glu Met Phe Thr Ile His Ala 
865                 870                 875                 880 


Tyr Val Gly Phe Thr Met Asp Lys Leu Val Gln Asn Ile Ala Arg Gln 
                885                 890                 895     


Leu His His Leu Val Ser Asp Asp Val Cys Leu Lys Val Val Glu Leu 
            900                 905                 910         


Tyr Leu Asn Glu Lys Lys Arg Gly Ala Ala Gly Gly Asn Leu Ser Ser 
        915                 920                 925             


Arg Cys Val Arg Ala Ala Arg Glu Thr Ser Tyr Gln Trp Lys Ala Glu 
    930                 935                 940                 


Arg Cys Met Ala Asp Glu Asn Cys Phe Lys Val Met Phe Leu Gln Arg 
945                 950                 955                 960 


Lys Gly Gln Val Ile Met Thr Ile Glu Leu Leu Asp Thr Glu Glu Ala 
                965                 970                 975     


Gln Thr Glu Asp Pro Val Glu Val Gln His Leu Ala Arg Tyr Val Glu 
            980                 985                 990         


Gln Tyr Val Gly Thr Glu Gly Ala  Ser Ser Ser Pro Thr  Glu Gly Phe 
        995                 1000                 1005             


Leu Leu  Lys Pro Val Phe Leu  Gln Arg Asn Leu Lys  Lys Phe Arg 
    1010                 1015                 1020             


Arg Arg  Trp Gln Ser Glu Gln  Ala Arg Ala Leu Arg  Gly Glu Ala 
    1025                 1030                 1035             


Arg Ser  Ser Trp Lys Arg Leu  Val Gly Val Glu Ser  Ala Cys Asp 
    1040                 1045                 1050             


Val Asp  Cys Arg Phe Lys Leu  Ser Thr His Lys Met  Val Phe Ile 
    1055                 1060                 1065             


Val Asn  Ser Glu Asp Tyr Met  Tyr Arg Arg Gly Thr  Leu Cys Arg 
    1070                 1075                 1080             


Ala Lys  Gln Val Gln Pro Leu  Val Leu Leu Arg His  His Gln His 
    1085                 1090                 1095             


Phe Glu  Glu Trp His Ser Arg  Trp Leu Glu Asp Asn  Val Thr Val 
    1100                 1105                 1110             


Glu Ala  Ala Ser Leu Val Gln  Asp Trp Leu Met Gly  Glu Glu Asp 
    1115                 1120                 1125             


Glu Asp  Met Val Pro Cys Lys  Thr Leu Cys Glu Thr  Val His Val 
    1130                 1135                 1140             


His Gly  Leu Pro Val Thr Arg  Tyr Arg Val Gln Tyr  Ser Arg Arg 
    1145                 1150                 1155             


Pro Ala  Ser Pro 
    1160         


<210>  3928
<211>  847
<212>  PRT
<213>  homo sapiens

<400>  3928

Met Phe Lys Cys Trp Ser Val Val Leu Val Leu Gly Phe Ile Phe Leu 
1               5                   10                  15      


Glu Ser Glu Gly Arg Pro Thr Lys Glu Gly Gly Tyr Gly Leu Lys Ser 
            20                  25                  30          


Tyr Gln Pro Leu Met Arg Leu Arg His Lys Gln Glu Lys Asn Gln Glu 
        35                  40                  45              


Ser Ser Arg Val Lys Gly Phe Met Ile Gln Asp Gly Pro Phe Gly Ser 
    50                  55                  60                  


Cys Glu Asn Lys Tyr Cys Gly Leu Gly Arg His Cys Val Thr Ser Arg 
65                  70                  75                  80  


Glu Thr Gly Gln Ala Glu Cys Ala Cys Met Asp Leu Cys Lys Arg His 
                85                  90                  95      


Tyr Lys Pro Val Cys Gly Ser Asp Gly Glu Phe Tyr Glu Asn His Cys 
            100                 105                 110         


Glu Val His Arg Ala Ala Cys Leu Lys Lys Gln Lys Ile Thr Ile Val 
        115                 120                 125             


His Asn Glu Asp Cys Phe Phe Lys Gly Asp Lys Cys Lys Thr Thr Glu 
    130                 135                 140                 


Tyr Ser Lys Met Lys Asn Met Leu Leu Asp Leu Gln Asn Gln Lys Tyr 
145                 150                 155                 160 


Ile Met Gln Glu Asn Glu Asn Pro Asn Gly Asp Asp Ile Ser Arg Lys 
                165                 170                 175     


Lys Leu Leu Val Asp Gln Met Phe Lys Tyr Phe Asp Ala Asp Ser Asn 
            180                 185                 190         


Gly Leu Val Asp Ile Asn Glu Leu Thr Gln Val Ile Lys Gln Glu Glu 
        195                 200                 205             


Leu Gly Lys Asp Leu Phe Asp Cys Thr Leu Tyr Val Leu Leu Lys Tyr 
    210                 215                 220                 


Asp Asp Phe Asn Ala Asp Lys His Leu Ala Leu Glu Glu Phe Tyr Arg 
225                 230                 235                 240 


Ala Phe Gln Val Ile Gln Leu Ser Leu Pro Glu Asp Gln Lys Leu Ser 
                245                 250                 255     


Ile Thr Ala Ala Thr Val Gly Gln Ser Ala Val Leu Ser Cys Ala Ile 
            260                 265                 270         


Gln Gly Thr Leu Arg Pro Pro Ile Ile Trp Lys Arg Asn Asn Ile Ile 
        275                 280                 285             


Leu Asn Asn Leu Asp Leu Glu Asp Ile Asn Asp Phe Gly Asp Asp Gly 
    290                 295                 300                 


Ser Leu Tyr Ile Thr Lys Val Thr Thr Thr His Val Gly Asn Tyr Thr 
305                 310                 315                 320 


Cys Tyr Ala Asp Gly Tyr Glu Gln Val Tyr Gln Thr His Ile Phe Gln 
                325                 330                 335     


Val Asn Val Pro Pro Val Ile Arg Val Tyr Pro Glu Ser Gln Ala Arg 
            340                 345                 350         


Glu Pro Gly Val Thr Ala Ser Leu Arg Cys His Ala Glu Gly Ile Pro 
        355                 360                 365             


Lys Pro Gln Leu Gly Trp Leu Lys Asn Gly Ile Asp Ile Thr Pro Lys 
    370                 375                 380                 


Leu Ser Lys Gln Leu Thr Leu Gln Ala Asn Gly Ser Glu Val His Ile 
385                 390                 395                 400 


Ser Asn Val Arg Tyr Glu Asp Thr Gly Ala Tyr Thr Cys Ile Ala Lys 
                405                 410                 415     


Asn Glu Ala Gly Val Asp Glu Asp Ile Ser Ser Leu Phe Val Glu Asp 
            420                 425                 430         


Ser Ala Arg Lys Thr Leu Ala Asn Ile Leu Trp Arg Glu Glu Gly Leu 
        435                 440                 445             


Gly Ile Gly Asn Met Phe Tyr Val Phe Tyr Glu Asp Gly Ile Lys Val 
    450                 455                 460                 


Ile Gln Pro Ile Glu Cys Glu Phe Gln Arg His Ile Lys Pro Ser Glu 
465                 470                 475                 480 


Lys Leu Leu Gly Phe Gln Asp Glu Val Cys Pro Lys Ala Glu Gly Asp 
                485                 490                 495     


Glu Val Gln Arg Cys Val Trp Ala Ser Ala Val Asn Val Lys Asp Lys 
            500                 505                 510         


Phe Ile Tyr Val Ala Gln Pro Thr Leu Asp Arg Val Leu Ile Val Asp 
        515                 520                 525             


Val Gln Ser Gln Lys Val Val Gln Ala Val Ser Thr Asp Pro Val Pro 
    530                 535                 540                 


Val Lys Leu His Tyr Asp Lys Ser His Asp Gln Val Trp Val Leu Ser 
545                 550                 555                 560 


Trp Gly Thr Leu Glu Lys Thr Ser Pro Thr Leu Gln Val Ile Thr Leu 
                565                 570                 575     


Ala Ser Gly Asn Val Pro His His Thr Ile His Thr Gln Pro Val Gly 
            580                 585                 590         


Lys Gln Phe Asp Arg Val Asp Asp Phe Phe Ile Pro Thr Thr Thr Leu 
        595                 600                 605             


Ile Ile Thr His Met Arg Phe Gly Phe Ile Leu His Lys Asp Glu Ala 
    610                 615                 620                 


Ala Leu Gln Lys Ile Asp Leu Glu Thr Met Ser Tyr Ile Lys Thr Ile 
625                 630                 635                 640 


Asn Leu Lys Asp Tyr Lys Cys Val Pro Gln Ser Leu Ala Tyr Thr His 
                645                 650                 655     


Leu Gly Gly Tyr Tyr Phe Ile Gly Cys Lys Pro Asp Ser Thr Gly Ala 
            660                 665                 670         


Val Ser Pro Gln Val Met Val Asp Gly Val Thr Asp Ser Val Ile Gly 
        675                 680                 685             


Phe Asn Ser Asp Val Thr Gly Thr Pro Tyr Val Ser Pro Asp Gly His 
    690                 695                 700                 


Tyr Leu Val Ser Ile Asn Asp Val Lys Gly Leu Val Arg Val Gln Tyr 
705                 710                 715                 720 


Ile Thr Ile Arg Gly Glu Ile Gln Glu Ala Phe Asp Ile Tyr Thr Asn 
                725                 730                 735     


Leu His Ile Ser Asp Leu Ala Phe Gln Pro Ser Phe Thr Glu Ala His 
            740                 745                 750         


Gln Tyr Asn Ile Tyr Gly Ser Ser Ser Thr Gln Thr Asp Val Leu Phe 
        755                 760                 765             


Val Glu Leu Ser Ser Gly Lys Val Lys Met Ile Lys Ser Leu Lys Glu 
    770                 775                 780                 


Pro Leu Lys Ala Glu Glu Trp Pro Trp Asn Arg Lys Asn Arg Gln Ile 
785                 790                 795                 800 


Gln Asp Ser Gly Leu Phe Gly Gln Tyr Leu Met Thr Pro Ser Lys Asp 
                805                 810                 815     


Ser Leu Phe Ile Leu Asp Gly Arg Leu Asn Lys Leu Asn Cys Glu Ile 
            820                 825                 830         


Thr Glu Val Glu Lys Gly Asn Thr Val Ile Trp Val Gly Asp Ala 
        835                 840                 845         


<210>  3929
<211>  317
<212>  PRT
<213>  homo sapiens

<400>  3929

Met Val Arg Ala Arg His Gln Pro Gly Gly Leu Cys Leu Leu Leu Leu 
1               5                   10                  15      


Leu Leu Cys Gln Phe Met Glu Asp Arg Ser Ala Gln Ala Gly Asn Cys 
            20                  25                  30          


Trp Leu Arg Gln Ala Lys Asn Gly Arg Cys Gln Val Leu Tyr Lys Thr 
        35                  40                  45              


Glu Leu Ser Lys Glu Glu Cys Cys Ser Thr Gly Arg Leu Ser Thr Ser 
    50                  55                  60                  


Trp Thr Glu Glu Asp Val Asn Asp Asn Thr Leu Phe Lys Trp Met Ile 
65                  70                  75                  80  


Phe Asn Gly Gly Ala Pro Asn Cys Ile Pro Cys Lys Glu Thr Cys Glu 
                85                  90                  95      


Asn Val Asp Cys Gly Pro Gly Lys Lys Cys Arg Met Asn Lys Lys Asn 
            100                 105                 110         


Lys Pro Arg Cys Val Cys Ala Pro Asp Cys Ser Asn Ile Thr Trp Lys 
        115                 120                 125             


Gly Pro Val Cys Gly Leu Asp Gly Lys Thr Tyr Arg Asn Glu Cys Ala 
    130                 135                 140                 


Leu Leu Lys Ala Arg Cys Lys Glu Gln Pro Glu Leu Glu Val Gln Tyr 
145                 150                 155                 160 


Gln Gly Arg Cys Lys Lys Thr Cys Arg Asp Val Phe Cys Pro Gly Ser 
                165                 170                 175     


Ser Thr Cys Val Val Asp Gln Thr Asn Asn Ala Tyr Cys Val Thr Cys 
            180                 185                 190         


Asn Arg Ile Cys Pro Glu Pro Ala Ser Ser Glu Gln Tyr Leu Cys Gly 
        195                 200                 205             


Asn Asp Gly Val Thr Tyr Ser Ser Ala Cys His Leu Arg Lys Ala Thr 
    210                 215                 220                 


Cys Leu Leu Gly Arg Ser Ile Gly Leu Ala Tyr Glu Gly Lys Cys Ile 
225                 230                 235                 240 


Lys Ala Lys Ser Cys Glu Asp Ile Gln Cys Thr Gly Gly Lys Lys Cys 
                245                 250                 255     


Leu Trp Asp Phe Lys Val Gly Arg Gly Arg Cys Ser Leu Cys Asp Glu 
            260                 265                 270         


Leu Cys Pro Asp Ser Lys Ser Asp Glu Pro Val Cys Ala Ser Asp Asn 
        275                 280                 285             


Ala Thr Tyr Ala Ser Glu Cys Ala Met Lys Glu Ala Ala Cys Ser Ser 
    290                 295                 300                 


Gly Val Leu Leu Glu Val Lys His Ser Gly Ser Cys Asn 
305                 310                 315         


<210>  3930
<211>  204
<212>  PRT
<213>  homo sapiens

<400>  3930

Met Ala Ala Ala Gly Trp Arg Asp Gly Ser Gly Gln Glu Lys Tyr Arg 
1               5                   10                  15      


Leu Val Val Val Gly Gly Gly Gly Val Gly Lys Ser Ala Leu Thr Ile 
            20                  25                  30          


Gln Phe Ile Gln Ser Tyr Phe Val Thr Asp Tyr Asp Pro Thr Ile Glu 
        35                  40                  45              


Asp Ser Tyr Thr Lys Gln Cys Val Ile Asp Asp Arg Ala Ala Arg Leu 
    50                  55                  60                  


Asp Ile Leu Asp Thr Ala Gly Gln Glu Glu Phe Gly Ala Met Arg Glu 
65                  70                  75                  80  


Gln Tyr Met Arg Thr Gly Glu Gly Phe Leu Leu Val Phe Ser Val Thr 
                85                  90                  95      


Asp Arg Gly Ser Phe Glu Glu Ile Tyr Lys Phe Gln Arg Gln Ile Leu 
            100                 105                 110         


Arg Val Lys Asp Arg Asp Glu Phe Pro Met Ile Leu Ile Gly Asn Lys 
        115                 120                 125             


Ala Asp Leu Asp His Gln Arg Gln Val Thr Gln Glu Glu Gly Gln Gln 
    130                 135                 140                 


Leu Ala Arg Gln Leu Lys Val Thr Tyr Met Glu Ala Ser Ala Lys Ile 
145                 150                 155                 160 


Arg Met Asn Val Asp Gln Ala Phe His Glu Leu Val Arg Val Ile Arg 
                165                 170                 175     


Lys Phe Gln Glu Gln Glu Cys Pro Pro Ser Pro Glu Pro Thr Arg Lys 
            180                 185                 190         


Glu Lys Asp Lys Lys Gly Cys His Cys Val Ile Phe 
        195                 200                 


<210>  3931
<211>  1651
<212>  PRT
<213>  homo sapiens

<400>  3931

Met Ser Ala Gly Gly Arg Asp Glu Glu Arg Arg Lys Leu Ala Asp Ile 
1               5                   10                  15      


Ile His His Trp Asn Ala Asn Arg Leu Asp Leu Phe Glu Ile Ser Gln 
            20                  25                  30          


Pro Thr Glu Asp Leu Glu Phe His Gly Val Met Arg Phe Tyr Phe Gln 
        35                  40                  45              


Asp Lys Ala Ala Gly Asn Phe Ala Thr Lys Cys Ile Arg Val Ser Ser 
    50                  55                  60                  


Thr Ala Thr Thr Gln Asp Val Ile Glu Thr Leu Ala Glu Lys Phe Arg 
65                  70                  75                  80  


Pro Asp Met Arg Met Leu Ser Ser Pro Lys Tyr Ser Leu Tyr Glu Val 
                85                  90                  95      


His Val Ser Gly Glu Arg Arg Leu Asp Ile Asp Glu Lys Pro Leu Val 
            100                 105                 110         


Val Gln Leu Asn Trp Asn Lys Asp Asp Arg Glu Gly Arg Phe Val Leu 
        115                 120                 125             


Lys Asn Glu Asn Asp Ala Ile Pro Pro Lys Lys Ala Gln Ser Asn Gly 
    130                 135                 140                 


Pro Glu Lys Gln Glu Lys Glu Gly Val Ile Gln Asn Phe Lys Arg Thr 
145                 150                 155                 160 


Leu Ser Lys Lys Glu Lys Lys Glu Lys Lys Lys Arg Glu Lys Glu Ala 
                165                 170                 175     


Leu Arg Gln Ala Ser Asp Lys Asp Asp Arg Pro Phe Gln Gly Glu Asp 
            180                 185                 190         


Val Glu Asn Ser Arg Leu Ala Ala Glu Val Tyr Lys Asp Met Pro Glu 
        195                 200                 205             


Thr Ser Phe Thr Arg Thr Ile Ser Asn Pro Glu Val Val Met Lys Arg 
    210                 215                 220                 


Arg Arg Gln Gln Lys Leu Glu Lys Arg Met Gln Glu Phe Arg Ser Ser 
225                 230                 235                 240 


Asp Gly Arg Pro Asp Ser Gly Gly Thr Leu Arg Ile Tyr Ala Asp Ser 
                245                 250                 255     


Leu Lys Pro Asn Ile Pro Tyr Lys Thr Ile Leu Leu Ser Thr Thr Asp 
            260                 265                 270         


Pro Ala Asp Phe Ala Val Ala Glu Ala Leu Glu Lys Tyr Gly Leu Glu 
        275                 280                 285             


Lys Glu Asn Pro Lys Asp Tyr Cys Ile Ala Arg Val Met Leu Pro Pro 
    290                 295                 300                 


Gly Ala Gln His Ser Asp Glu Lys Gly Ala Lys Glu Ile Ile Leu Asp 
305                 310                 315                 320 


Asp Asp Glu Cys Pro Leu Gln Ile Phe Arg Glu Trp Pro Ser Asp Lys 
                325                 330                 335     


Gly Ile Leu Val Phe Gln Leu Lys Arg Arg Pro Pro Asp His Ile Pro 
            340                 345                 350         


Lys Lys Thr Lys Lys His Leu Glu Gly Lys Thr Pro Lys Gly Lys Glu 
        355                 360                 365             


Arg Ala Asp Gly Ser Gly Tyr Gly Ser Thr Leu Pro Pro Glu Lys Leu 
    370                 375                 380                 


Pro Tyr Leu Val Glu Leu Ser Pro Gly Arg Arg Asn His Phe Ala Tyr 
385                 390                 395                 400 


Tyr Asn Tyr His Thr Tyr Glu Asp Gly Ser Asp Ser Arg Asp Lys Pro 
                405                 410                 415     


Lys Leu Tyr Arg Leu Gln Leu Ser Val Thr Glu Val Gly Thr Glu Lys 
            420                 425                 430         


Leu Asp Asp Asn Ser Ile Gln Leu Phe Gly Pro Gly Ile Gln Pro His 
        435                 440                 445             


His Cys Asp Leu Thr Asn Met Asp Gly Val Val Thr Val Thr Pro Arg 
    450                 455                 460                 


Ser Met Asp Ala Glu Thr Tyr Val Glu Gly Gln Arg Ile Ser Glu Thr 
465                 470                 475                 480 


Thr Met Leu Gln Ser Gly Met Lys Val Gln Phe Gly Ala Ser His Val 
                485                 490                 495     


Phe Lys Phe Val Asp Pro Ser Gln Asp His Ala Leu Ala Lys Arg Ser 
            500                 505                 510         


Val Asp Gly Gly Leu Met Val Lys Gly Pro Arg His Lys Pro Gly Ile 
        515                 520                 525             


Val Gln Glu Thr Thr Phe Asp Leu Gly Gly Asp Ile His Ser Gly Thr 
    530                 535                 540                 


Ala Leu Pro Thr Ser Lys Ser Thr Thr Arg Leu Asp Ser Asp Arg Val 
545                 550                 555                 560 


Ser Ser Ala Ser Ser Thr Ala Glu Arg Gly Met Val Lys Pro Met Ile 
                565                 570                 575     


Arg Val Glu Gln Gln Pro Asp Tyr Arg Arg Gln Glu Ser Arg Thr Gln 
            580                 585                 590         


Asp Ala Ser Gly Pro Glu Leu Ile Leu Pro Ala Ser Ile Glu Phe Arg 
        595                 600                 605             


Glu Ser Ser Glu Asp Ser Phe Leu Ser Ala Ile Ile Asn Tyr Thr Asn 
    610                 615                 620                 


Ser Ser Thr Val His Phe Lys Leu Ser Pro Thr Tyr Val Leu Tyr Met 
625                 630                 635                 640 


Ala Cys Arg Tyr Val Leu Ser Asn Gln Tyr Arg Pro Asp Ile Ser Pro 
                645                 650                 655     


Thr Glu Arg Thr His Lys Val Ile Ala Val Val Asn Lys Met Val Ser 
            660                 665                 670         


Met Met Glu Gly Val Ile Gln Lys Gln Lys Asn Ile Ala Gly Ala Leu 
        675                 680                 685             


Ala Phe Trp Met Ala Asn Ala Ser Glu Leu Leu Asn Phe Ile Lys Gln 
    690                 695                 700                 


Asp Arg Asp Leu Ser Arg Ile Thr Leu Asp Ala Gln Asp Val Leu Ala 
705                 710                 715                 720 


His Leu Val Gln Met Ala Phe Lys Tyr Leu Val His Cys Leu Gln Ser 
                725                 730                 735     


Glu Leu Asn Asn Tyr Met Pro Ala Phe Leu Asp Asp Pro Glu Glu Asn 
            740                 745                 750         


Ser Leu Gln Arg Pro Lys Ile Asp Asp Val Leu His Thr Leu Thr Gly 
        755                 760                 765             


Ala Met Ser Leu Leu Arg Arg Cys Arg Val Asn Ala Ala Leu Thr Ile 
    770                 775                 780                 


Gln Leu Phe Ser Gln Leu Phe His Phe Ile Asn Met Trp Leu Phe Asn 
785                 790                 795                 800 


Arg Leu Val Thr Asp Pro Asp Ser Gly Leu Cys Ser His Tyr Trp Gly 
                805                 810                 815     


Ala Ile Ile Arg Gln Gln Leu Gly His Ile Glu Ala Trp Ala Glu Lys 
            820                 825                 830         


Gln Gly Leu Glu Leu Ala Ala Asp Cys His Leu Ser Arg Ile Val Gln 
        835                 840                 845             


Ala Thr Thr Leu Leu Thr Met Asp Lys Tyr Ala Pro Asp Asp Ile Pro 
    850                 855                 860                 


Asn Ile Asn Ser Thr Cys Phe Lys Leu Asn Ser Leu Gln Leu Gln Ala 
865                 870                 875                 880 


Leu Leu Gln Asn Tyr His Cys Ala Pro Asp Glu Pro Phe Ile Pro Thr 
                885                 890                 895     


Asp Leu Ile Glu Asn Val Val Thr Val Ala Glu Asn Thr Ala Asp Glu 
            900                 905                 910         


Leu Ala Arg Ser Asp Gly Arg Glu Val Gln Leu Glu Glu Asp Pro Asp 
        915                 920                 925             


Leu Gln Leu Pro Phe Leu Leu Pro Glu Asp Gly Tyr Ser Cys Asp Val 
    930                 935                 940                 


Val Arg Asn Ile Pro Asn Gly Leu Gln Glu Phe Leu Asp Pro Leu Cys 
945                 950                 955                 960 


Gln Arg Gly Phe Cys Arg Leu Ile Pro His Thr Arg Ser Pro Gly Thr 
                965                 970                 975     


Trp Thr Ile Tyr Phe Glu Gly Ala Asp Tyr Glu Ser His Leu Leu Arg 
            980                 985                 990         


Glu Asn Thr Glu Leu Ala Gln Pro  Leu Arg Lys Glu Pro  Glu Ile Ile 
        995                 1000                 1005             


Thr Val  Thr Leu Lys Lys Gln  Asn Gly Met Gly Leu  Ser Ile Val 
    1010                 1015                 1020             


Ala Ala  Lys Gly Ala Gly Gln  Asp Lys Leu Gly Ile  Tyr Val Lys 
    1025                 1030                 1035             


Ser Val  Val Lys Gly Gly Ala  Ala Asp Val Asp Gly  Arg Leu Ala 
    1040                 1045                 1050             


Ala Gly  Asp Gln Leu Leu Ser  Val Asp Gly Arg Ser  Leu Val Gly 
    1055                 1060                 1065             


Leu Ser  Gln Glu Arg Ala Ala  Glu Leu Met Thr Arg  Thr Ser Ser 
    1070                 1075                 1080             


Val Val  Thr Leu Glu Val Ala  Lys Gln Gly Ala Ile  Tyr His Gly 
    1085                 1090                 1095             


Leu Ala  Thr Leu Leu Asn Gln  Pro Ser Pro Met Met  Gln Arg Ile 
    1100                 1105                 1110             


Ser Asp  Arg Arg Gly Ser Gly  Lys Pro Arg Pro Lys  Ser Glu Gly 
    1115                 1120                 1125             


Phe Glu  Leu Tyr Asn Asn Ser  Thr Gln Asn Gly Ser  Pro Glu Ser 
    1130                 1135                 1140             


Pro Gln  Leu Pro Trp Ala Glu  Tyr Ser Glu Pro Lys  Lys Leu Pro 
    1145                 1150                 1155             


Gly Asp  Asp Arg Leu Met Lys  Asn Arg Ala Asp His  Arg Ser Ser 
    1160                 1165                 1170             


Pro Asn  Val Ala Asn Gln Pro  Pro Ser Pro Gly Gly  Lys Ser Ala 
    1175                 1180                 1185             


Tyr Ala  Ser Gly Thr Thr Ala  Lys Ile Thr Ser Val  Ser Thr Gly 
    1190                 1195                 1200             


Asn Leu  Cys Thr Glu Glu Gln  Thr Pro Pro Pro Arg  Pro Glu Ala 
    1205                 1210                 1215             


Tyr Pro  Ile Pro Thr Gln Thr  Tyr Thr Arg Glu Tyr  Phe Thr Phe 
    1220                 1225                 1230             


Pro Ala  Ser Lys Ser Gln Asp  Arg Met Ala Pro Pro  Gln Asn Gln 
    1235                 1240                 1245             


Trp Pro  Asn Tyr Glu Glu Lys  Pro His Met His Thr  Asp Ser Asn 
    1250                 1255                 1260             


His Ser  Ser Ile Ala Ile Gln  Arg Val Thr Arg Ser  Gln Glu Glu 
    1265                 1270                 1275             


Leu Arg  Glu Asp Lys Ala Tyr  Gln Leu Glu Arg His  Arg Ile Glu 
    1280                 1285                 1290             


Ala Ala  Met Asp Arg Lys Ser  Asp Ser Asp Met Trp  Ile Asn Gln 
    1295                 1300                 1305             


Ser Ser  Ser Leu Asp Ser Ser  Thr Ser Ser Gln Glu  His Leu Asn 
    1310                 1315                 1320             


His Ser  Ser Lys Ser Val Thr  Pro Ala Ser Thr Leu  Thr Lys Ser 
    1325                 1330                 1335             


Gly Pro  Gly Arg Trp Lys Thr  Pro Ala Ala Ile Pro  Ala Thr Pro 
    1340                 1345                 1350             


Val Ala  Val Ser Gln Pro Ile  Arg Thr Asp Leu Pro  Pro Pro Pro 
    1355                 1360                 1365             


Pro Pro  Pro Pro Val His Tyr  Ala Gly Asp Phe Asp  Gly Met Ser 
    1370                 1375                 1380             


Met Asp  Leu Pro Leu Pro Pro  Pro Pro Ser Ala Asn  Gln Ile Gly 
    1385                 1390                 1395             


Leu Pro  Ser Ala Gln Val Ala  Ala Ala Glu Arg Arg  Lys Arg Glu 
    1400                 1405                 1410             


Glu His  Gln Arg Trp Tyr Glu  Lys Glu Lys Ala Arg  Leu Glu Glu 
    1415                 1420                 1425             


Glu Arg  Glu Arg Lys Arg Arg  Glu Gln Glu Arg Lys  Leu Gly Gln 
    1430                 1435                 1440             


Met Arg  Thr Gln Ser Leu Asn  Pro Ala Pro Phe Ser  Pro Leu Thr 
    1445                 1450                 1455             


Ala Gln  Gln Met Lys Pro Glu  Lys Pro Ser Thr Leu  Gln Arg Pro 
    1460                 1465                 1470             


Gln Glu  Thr Val Ile Arg Glu  Leu Gln Pro Gln Gln  Gln Pro Arg 
    1475                 1480                 1485             


Thr Ile  Glu Arg Arg Asp Leu  Gln Tyr Ile Thr Val  Ser Lys Glu 
    1490                 1495                 1500             


Glu Leu  Ser Ser Gly Asp Ser  Leu Ser Pro Asp Pro  Trp Lys Arg 
    1505                 1510                 1515             


Asp Ala  Lys Glu Lys Leu Glu  Lys Gln Gln Gln Met  His Ile Val 
    1520                 1525                 1530             


Asp Met  Leu Ser Lys Glu Ile  Gln Glu Leu Gln Ser  Lys Pro Asp 
    1535                 1540                 1545             


Arg Ser  Ala Glu Glu Ser Asp  Arg Leu Arg Lys Leu  Met Leu Glu 
    1550                 1555                 1560             


Trp Gln  Phe Gln Lys Arg Leu  Gln Glu Ser Lys Gln  Lys Asp Glu 
    1565                 1570                 1575             


Asp Asp  Glu Glu Glu Glu Asp  Asp Asp Val Asp Thr  Met Leu Ile 
    1580                 1585                 1590             


Met Gln  Arg Leu Glu Ala Glu  Arg Arg Ala Arg Asp  Glu Glu Arg 
    1595                 1600                 1605             


Arg Arg  Gln Gln Gln Leu Glu  Glu Met Arg Lys Arg  Glu Ala Glu 
    1610                 1615                 1620             


Asp Arg  Ala Arg Gln Glu Glu  Glu Arg Arg Arg Gln  Glu Glu Glu 
    1625                 1630                 1635             


Arg Thr  Lys Arg Asp Ala Glu  Glu Lys Val Met Val  Leu 
    1640                 1645                 1650     


<210>  3932
<211>  171
<212>  PRT
<213>  homo sapiens

<400>  3932

Met Thr Pro Thr Ala Phe Phe Ser Ser Pro Asn Thr Ala Gly Gly Met 
1               5                   10                  15      


Thr Pro Thr Ala Ser Ser Ser Gln His Thr Ala Gly Gly Met Thr Pro 
            20                  25                  30          


Thr Val Phe Ser Ser Gln His Thr Ala Gly Gly Met Thr Pro Thr Val 
        35                  40                  45              


Phe Ser Ser Gln His Thr Ala Gly Gly Met Thr Pro Thr Ala Ser Ser 
    50                  55                  60                  


Ser Gln His Thr Ala Gly Gly Met Thr Pro Thr Val Phe Ser Ser Pro 
65                  70                  75                  80  


His Thr Ala Gly Gly Met Thr Pro Thr Val Phe Ser Ser Pro His Thr 
                85                  90                  95      


Ala Gly Gly Met Thr Pro Thr Val Phe Ser Ser Pro His Thr Ala Gly 
            100                 105                 110         


Gly Met Thr Pro Thr Ala Ser Ser Ser Gln His Thr Ala Gly Val Met 
        115                 120                 125             


Thr Pro Thr Ala Ser Ser Phe Pro Thr His Cys Arg Gly Asn Asp Pro 
    130                 135                 140                 


His Cys Leu Leu Leu Pro Gln His Cys Arg Gly Asn Asp Pro His Cys 
145                 150                 155                 160 


Leu Leu Leu Pro Thr His Thr Leu Gln Gly Glu 
                165                 170     


<210>  3933
<211>  575
<212>  PRT
<213>  homo sapiens

<400>  3933

Met Ala Lys Pro Phe Phe Arg Leu Gln Lys Phe Leu Arg Arg Thr Gln 
1               5                   10                  15      


Phe Leu Leu Phe Phe Leu Thr Ala Ala Tyr Leu Met Thr Gly Ser Leu 
            20                  25                  30          


Leu Leu Leu Gln Arg Val Arg Val Ala Leu Pro Gln Gly Pro Arg Ala 
        35                  40                  45              


Pro Gly Pro Leu Gln Thr Leu Pro Val Ala Ala Val Ala Leu Gly Val 
    50                  55                  60                  


Gly Leu Leu Asp Ser Arg Ala Leu His Asp Pro Arg Val Ser Pro Glu 
65                  70                  75                  80  


Leu Leu Leu Gly Val Asp Met Leu Gln Ser Pro Leu Thr Arg Pro Arg 
                85                  90                  95      


Pro Gly Pro Arg Trp Leu Arg Ser Arg Asn Ser Glu Leu Arg Gln Leu 
            100                 105                 110         


Arg Arg Arg Trp Phe His His Phe Met Ser Asp Ser Gln Gly Pro Pro 
        115                 120                 125             


Ala Leu Gly Pro Glu Ala Ala Arg Pro Ala Ile His Ser Arg Gly Thr 
    130                 135                 140                 


Tyr Ile Gly Cys Phe Ser Asp Asp Gly His Glu Arg Thr Leu Lys Gly 
145                 150                 155                 160 


Ala Val Phe Tyr Asp Leu Arg Lys Met Thr Val Ser His Cys Gln Asp 
                165                 170                 175     


Ala Cys Ala Glu Arg Ser Tyr Val Tyr Ala Gly Leu Glu Ala Gly Ala 
            180                 185                 190         


Glu Cys Tyr Cys Gly Asn Arg Leu Pro Ala Val Ser Val Gly Leu Glu 
        195                 200                 205             


Glu Cys Asn His Glu Cys Lys Gly Glu Lys Gly Ser Val Cys Gly Ala 
    210                 215                 220                 


Val Asp Arg Leu Ser Val Tyr Arg Val Asp Glu Leu Gln Pro Gly Ser 
225                 230                 235                 240 


Arg Lys Arg Arg Thr Ala Thr Tyr Arg Gly Cys Phe Arg Leu Pro Glu 
                245                 250                 255     


Asn Ile Thr His Ala Phe Pro Ser Ser Leu Ile Gln Ala Asn Val Thr 
            260                 265                 270         


Val Gly Thr Cys Ser Gly Phe Cys Ser Gln Lys Glu Phe Pro Leu Ala 
        275                 280                 285             


Ile Leu Arg Gly Trp Glu Cys Tyr Cys Ala Tyr Pro Thr Pro Arg Phe 
    290                 295                 300                 


Asn Leu Arg Asp Ala Met Asp Ser Ser Val Cys Gly Gln Asp Pro Glu 
305                 310                 315                 320 


Ala Gln Arg Leu Ala Glu Tyr Cys Glu Val Tyr Gln Thr Pro Val Gln 
                325                 330                 335     


Asp Thr Arg Cys Thr Asp Arg Arg Phe Leu Pro Asn Lys Ser Lys Val 
            340                 345                 350         


Phe Val Ala Leu Ser Ser Phe Pro Gly Ala Gly Asn Thr Trp Ala Arg 
        355                 360                 365             


His Leu Ile Glu His Ala Thr Gly Phe Tyr Thr Gly Ser Tyr Tyr Phe 
    370                 375                 380                 


Asp Gly Thr Leu Tyr Asn Lys Gly Phe Lys Gly Glu Lys Asp His Trp 
385                 390                 395                 400 


Arg Ser Arg Arg Thr Ile Cys Val Lys Thr His Glu Ser Gly Arg Arg 
                405                 410                 415     


Glu Ile Glu Met Phe Asp Ser Ala Ile Leu Leu Ile Arg Asn Pro Tyr 
            420                 425                 430         


Arg Ser Leu Val Ala Glu Phe Asn Arg Lys Cys Ala Gly His Leu Gly 
        435                 440                 445             


Tyr Ala Ala Asp Arg Asn Trp Lys Ser Lys Glu Trp Pro Asp Phe Val 
    450                 455                 460                 


Asn Ser Tyr Ala Ser Trp Trp Ser Ser His Val Leu Asp Trp Leu Lys 
465                 470                 475                 480 


Tyr Gly Lys Arg Leu Leu Val Val His Tyr Glu Glu Leu Arg Arg Ser 
                485                 490                 495     


Leu Val Pro Thr Leu Arg Glu Met Val Ala Phe Leu Asn Val Ser Val 
            500                 505                 510         


Ser Glu Glu Arg Leu Leu Cys Val Glu Asn Asn Lys Glu Gly Ser Phe 
        515                 520                 525             


Arg Arg Arg Gly Arg Arg Ser His Asp Pro Glu Pro Phe Thr Pro Glu 
    530                 535                 540                 


Met Lys Asp Leu Ile Asn Gly Tyr Ile Arg Thr Val Asp Gln Ala Leu 
545                 550                 555                 560 


Arg Asp His Asn Trp Thr Gly Leu Pro Arg Glu Tyr Val Pro Arg 
                565                 570                 575 


<210>  3934
<211>  261
<212>  PRT
<213>  homo sapiens

<400>  3934

Met Val Val Val Ala Ala Ala Pro Asn Pro Ala Asp Gly Thr Pro Lys 
1               5                   10                  15      


Val Leu Leu Leu Ser Gly Gln Pro Ala Ser Ala Ala Gly Ala Pro Ala 
            20                  25                  30          


Gly Gln Ala Leu Pro Leu Met Val Pro Ala Gln Arg Gly Ala Ser Pro 
        35                  40                  45              


Glu Ala Ala Ser Gly Gly Leu Pro Gln Ala Arg Lys Arg Gln Arg Leu 
    50                  55                  60                  


Thr His Leu Ser Pro Glu Glu Lys Ala Leu Arg Arg Lys Leu Lys Asn 
65                  70                  75                  80  


Arg Val Ala Ala Gln Thr Ala Arg Asp Arg Lys Lys Ala Arg Met Ser 
                85                  90                  95      


Glu Leu Glu Gln Gln Val Val Asp Leu Glu Glu Glu Asn Gln Lys Leu 
            100                 105                 110         


Leu Leu Glu Asn Gln Leu Leu Arg Glu Lys Thr His Gly Leu Val Val 
        115                 120                 125             


Glu Asn Gln Glu Leu Arg Gln Arg Leu Gly Met Asp Ala Leu Val Ala 
    130                 135                 140                 


Glu Glu Glu Ala Glu Ala Lys Gly Asn Glu Val Arg Pro Val Ala Gly 
145                 150                 155                 160 


Ser Ala Glu Ser Ala Ala Leu Arg Leu Arg Ala Pro Leu Gln Gln Val 
                165                 170                 175     


Gln Ala Gln Leu Ser Pro Leu Gln Asn Ile Ser Pro Trp Ile Leu Ala 
            180                 185                 190         


Val Leu Thr Leu Gln Ile Gln Ser Leu Ile Ser Cys Trp Ala Phe Trp 
        195                 200                 205             


Thr Thr Trp Thr Gln Ser Cys Ser Ser Asn Ala Leu Pro Gln Ser Leu 
    210                 215                 220                 


Pro Ala Trp Arg Ser Ser Gln Arg Ser Thr Gln Lys Asp Pro Val Pro 
225                 230                 235                 240 


Tyr Gln Pro Pro Phe Leu Cys Gln Trp Gly Arg His Gln Pro Ser Trp 
                245                 250                 255     


Lys Pro Leu Met Asn 
            260     


<210>  3935
<211>  1114
<212>  PRT
<213>  homo sapiens

<400>  3935

Met Leu Arg Gly Thr Met Thr Ala Trp Arg Gly Met Arg Pro Glu Val 
1               5                   10                  15      


Thr Leu Ala Cys Leu Leu Leu Ala Thr Ala Gly Cys Phe Ala Asp Leu 
            20                  25                  30          


Asn Glu Val Pro Gln Val Thr Val Gln Pro Ala Ser Thr Val Gln Lys 
        35                  40                  45              


Pro Gly Gly Thr Val Ile Leu Gly Cys Val Val Glu Pro Pro Arg Met 
    50                  55                  60                  


Asn Val Thr Trp Arg Leu Asn Gly Lys Glu Leu Asn Gly Ser Asp Asp 
65                  70                  75                  80  


Ala Leu Gly Val Leu Ile Thr His Gly Thr Leu Val Ile Thr Ala Leu 
                85                  90                  95      


Asn Asn His Thr Val Gly Arg Tyr Gln Cys Val Ala Arg Met Pro Ala 
            100                 105                 110         


Gly Ala Val Ala Ser Val Pro Ala Thr Val Thr Leu Ala Asn Leu Gln 
        115                 120                 125             


Asp Phe Lys Leu Asp Val Gln His Val Ile Glu Val Asp Glu Gly Asn 
    130                 135                 140                 


Thr Ala Val Ile Ala Cys His Leu Pro Glu Ser His Pro Lys Ala Gln 
145                 150                 155                 160 


Val Arg Tyr Ser Val Lys Gln Glu Trp Leu Glu Ala Ser Arg Gly Asn 
                165                 170                 175     


Tyr Leu Ile Met Pro Ser Gly Asn Leu Gln Ile Val Asn Ala Ser Gln 
            180                 185                 190         


Glu Asp Glu Gly Met Tyr Lys Cys Ala Ala Tyr Asn Pro Val Thr Gln 
        195                 200                 205             


Glu Val Lys Thr Ser Gly Ser Ser Asp Arg Leu Arg Val Arg Arg Ser 
    210                 215                 220                 


Thr Ala Glu Ala Ala Arg Ile Ile Tyr Pro Pro Glu Ala Gln Thr Ile 
225                 230                 235                 240 


Ile Val Thr Lys Gly Gln Ser Leu Ile Leu Glu Cys Val Ala Ser Gly 
                245                 250                 255     


Ile Pro Pro Pro Arg Val Thr Trp Ala Lys Asp Gly Ser Ser Val Thr 
            260                 265                 270         


Gly Tyr Asn Lys Thr Arg Phe Leu Leu Ser Asn Leu Leu Ile Asp Thr 
        275                 280                 285             


Thr Ser Glu Glu Asp Ser Gly Thr Tyr Arg Cys Met Ala Asp Asn Gly 
    290                 295                 300                 


Val Gly Gln Pro Gly Ala Ala Val Ile Leu Tyr Asn Val Gln Val Phe 
305                 310                 315                 320 


Glu Pro Pro Glu Val Thr Met Glu Leu Ser Gln Leu Val Ile Pro Trp 
                325                 330                 335     


Gly Gln Ser Ala Lys Leu Thr Cys Glu Val Arg Gly Asn Pro Pro Pro 
            340                 345                 350         


Ser Val Leu Trp Leu Arg Asn Ala Val Pro Leu Ile Ser Ser Gln Arg 
        355                 360                 365             


Leu Arg Leu Ser Arg Arg Ala Leu Arg Val Leu Ser Met Gly Pro Glu 
    370                 375                 380                 


Asp Glu Gly Val Tyr Gln Cys Met Ala Glu Asn Glu Val Gly Ser Ala 
385                 390                 395                 400 


His Ala Val Val Gln Leu Arg Thr Ser Arg Pro Ser Ile Thr Pro Arg 
                405                 410                 415     


Leu Trp Gln Asp Ala Glu Leu Ala Thr Gly Thr Pro Pro Val Ser Pro 
            420                 425                 430         


Ser Lys Leu Gly Asn Pro Glu Gln Met Leu Arg Gly Gln Pro Ala Leu 
        435                 440                 445             


Pro Arg Pro Pro Thr Ser Val Gly Pro Ala Ser Pro Gln Cys Pro Gly 
    450                 455                 460                 


Glu Lys Gly Gln Gly Ala Pro Ala Glu Ala Pro Ile Ile Leu Ser Ser 
465                 470                 475                 480 


Pro Arg Thr Ser Lys Thr Asp Ser Tyr Glu Leu Val Trp Arg Pro Arg 
                485                 490                 495     


His Glu Gly Ser Gly Arg Ala Pro Ile Leu Tyr Tyr Val Val Lys His 
            500                 505                 510         


Arg Lys Val Thr Asn Ser Ser Asp Asp Trp Thr Ile Ser Gly Ile Pro 
        515                 520                 525             


Ala Asn Gln His Arg Leu Thr Leu Thr Arg Leu Asp Pro Gly Ser Leu 
    530                 535                 540                 


Tyr Glu Val Glu Met Ala Ala Tyr Asn Cys Ala Gly Glu Gly Gln Thr 
545                 550                 555                 560 


Ala Met Val Thr Phe Arg Thr Gly Arg Arg Pro Lys Pro Glu Ile Met 
                565                 570                 575     


Ala Ser Lys Glu Gln Gln Ile Gln Arg Asp Asp Pro Gly Ala Ser Pro 
            580                 585                 590         


Gln Ser Ser Ser Gln Pro Asp His Gly Arg Leu Ser Pro Pro Glu Ala 
        595                 600                 605             


Pro Asp Arg Pro Thr Ile Ser Thr Ala Ser Glu Thr Ser Val Tyr Val 
    610                 615                 620                 


Thr Trp Ile Pro Arg Gly Asn Gly Gly Phe Pro Ile Gln Ser Phe Arg 
625                 630                 635                 640 


Val Glu Tyr Lys Lys Leu Lys Lys Val Gly Asp Trp Ile Leu Ala Thr 
                645                 650                 655     


Ser Ala Ile Pro Pro Ser Arg Leu Ser Val Glu Ile Thr Gly Leu Glu 
            660                 665                 670         


Lys Gly Thr Ser Tyr Lys Phe Arg Val Arg Ala Leu Asn Met Leu Gly 
        675                 680                 685             


Glu Ser Glu Pro Ser Ala Pro Ser Arg Pro Tyr Val Val Ser Gly Tyr 
    690                 695                 700                 


Ser Gly Arg Val Tyr Glu Arg Pro Val Ala Gly Pro Tyr Ile Thr Phe 
705                 710                 715                 720 


Thr Asp Ala Val Asn Glu Thr Thr Ile Met Leu Lys Trp Met Tyr Ile 
                725                 730                 735     


Pro Ala Ser Asn Asn Asn Thr Pro Ile His Gly Phe Tyr Ile Tyr Tyr 
            740                 745                 750         


Arg Pro Thr Asp Ser Asp Asn Asp Ser Asp Tyr Lys Lys Asp Met Val 
        755                 760                 765             


Glu Gly Asp Lys Tyr Trp His Ser Ile Ser His Leu Gln Pro Glu Thr 
    770                 775                 780                 


Ser Tyr Asp Ile Lys Met Gln Cys Phe Asn Glu Gly Gly Glu Ser Glu 
785                 790                 795                 800 


Phe Ser Asn Val Met Ile Cys Glu Thr Lys Ala Arg Lys Ser Ser Gly 
                805                 810                 815     


Gln Pro Gly Arg Leu Pro Pro Pro Thr Leu Ala Pro Pro Gln Pro Pro 
            820                 825                 830         


Leu Pro Glu Thr Ile Glu Arg Pro Val Gly Thr Gly Ala Met Val Ala 
        835                 840                 845             


Arg Ser Ser Asp Leu Pro Tyr Leu Ile Val Gly Val Val Leu Gly Ser 
    850                 855                 860                 


Ile Val Leu Ile Ile Val Thr Phe Ile Pro Phe Cys Leu Trp Arg Ala 
865                 870                 875                 880 


Trp Ser Lys Gln Lys His Thr Thr Asp Leu Gly Phe Pro Arg Ser Ala 
                885                 890                 895     


Leu Pro Pro Ser Cys Pro Tyr Thr Met Val Pro Leu Gly Gly Leu Pro 
            900                 905                 910         


Gly His Gln Ala Ser Gly Gln Pro Tyr Leu Ser Gly Ile Ser Gly Arg 
        915                 920                 925             


Ala Cys Ala Asn Gly Ile His Met Asn Arg Gly Cys Pro Ser Ala Ala 
    930                 935                 940                 


Val Gly Tyr Pro Gly Met Lys Pro Gln Gln His Cys Pro Gly Glu Leu 
945                 950                 955                 960 


Gln Gln Gln Ser Asp Thr Ser Ser Leu Leu Arg Gln Thr His Leu Gly 
                965                 970                 975     


Asn Gly Tyr Asp Pro Gln Ser His Gln Ile Thr Arg Gly Pro Lys Ser 
            980                 985                 990         


Ser Pro Asp Glu Gly Ser Phe Leu  Tyr Thr Leu Pro Asp  Asp Ser Thr 
        995                 1000                 1005             


His Gln  Leu Leu Gln Pro His  His Asp Cys Cys Gln  Arg Gln Glu 
    1010                 1015                 1020             


Gln Pro  Ala Ala Val Gly Gln  Ser Gly Val Arg Arg  Ala Pro Asp 
    1025                 1030                 1035             


Ser Pro  Val Leu Glu Ala Val  Trp Asp Pro Pro Phe  His Ser Gly 
    1040                 1045                 1050             


Pro Pro  Cys Cys Leu Gly Leu  Val Pro Val Glu Glu  Val Asp Ser 
    1055                 1060                 1065             


Pro Asp  Ser Cys Gln Val Ser  Gly Gly Asp Trp Cys  Pro Gln His 
    1070                 1075                 1080             


Pro Val  Gly Ala Tyr Val Gly  Gln Glu Pro Gly Met  Gln Leu Ser 
    1085                 1090                 1095             


Pro Gly  Pro Leu Val Arg Val  Ser Phe Glu Thr Pro  Pro Leu Thr 
    1100                 1105                 1110             


Ile 
    


<210>  3936
<211>  310
<212>  PRT
<213>  homo sapiens

<400>  3936

Met Lys Gly Gln Gln Lys Thr Ala Glu Thr Glu Glu Gly Thr Val Gln 
1               5                   10                  15      


Ile Gln Glu Gly Ala Val Ala Thr Gly Glu Asp Pro Thr Ser Val Ala 
            20                  25                  30          


Ile Ala Ser Ile Gln Ser Ala Ala Thr Phe Pro Asp Pro Asn Val Lys 
        35                  40                  45              


Tyr Val Phe Arg Thr Glu Asn Gly Gly Gln Val Met Tyr Arg Val Ile 
    50                  55                  60                  


Gln Val Ser Glu Gly Gln Leu Asp Gly Gln Thr Glu Gly Thr Gly Ala 
65                  70                  75                  80  


Ile Ser Gly Tyr Pro Ala Thr Gln Ser Met Thr Gln Ala Val Ile Gln 
                85                  90                  95      


Gly Ala Phe Thr Ser Asp Asp Ala Val Asp Thr Glu Gly Thr Ala Ala 
            100                 105                 110         


Glu Thr His Tyr Thr Tyr Phe Pro Ser Thr Ala Val Gly Asp Gly Ala 
        115                 120                 125             


Gly Gly Thr Thr Ser Gly Ser Thr Ala Ala Val Val Thr Thr Gln Gly 
    130                 135                 140                 


Ser Glu Ala Leu Leu Gly Gln Ala Thr Pro Pro Gly Thr Gly Gln Phe 
145                 150                 155                 160 


Phe Val Met Met Ser Pro Gln Glu Val Leu Gln Gly Gly Ser Gln Arg 
                165                 170                 175     


Ser Ile Ala Pro Arg Thr His Pro Tyr Ser Pro Lys Ser Glu Ala Pro 
            180                 185                 190         


Arg Thr Thr Arg Asp Glu Lys Arg Arg Ala Gln His Asn Glu Val Glu 
        195                 200                 205             


Arg Arg Arg Arg Asp Lys Ile Asn Asn Trp Ile Val Gln Leu Ser Lys 
    210                 215                 220                 


Ile Ile Pro Asp Cys Ser Met Glu Ser Thr Lys Ser Gly Gln Ser Lys 
225                 230                 235                 240 


Gly Gly Ile Leu Ser Lys Ala Cys Asp Tyr Ile Gln Glu Leu Arg Gln 
                245                 250                 255     


Ser Asn His Arg Leu Ser Glu Glu Leu Gln Gly Leu Asp Gln Leu Gln 
            260                 265                 270         


Leu Asp Asn Asp Val Leu Arg Gln Gln Val Glu Asp Leu Lys Asn Lys 
        275                 280                 285             


Asn Leu Leu Leu Arg Ala Gln Leu Arg His His Gly Leu Glu Val Val 
    290                 295                 300                 


Ile Lys Asn Asp Ser Asn 
305                 310 


<210>  3937
<211>  538
<212>  PRT
<213>  homo sapiens

<400>  3937

Met Val Glu Leu Val Ile Ser Pro Ser Leu Thr Val Asn Ser Asp Cys 
1               5                   10                  15      


Leu Asp Lys Leu Lys Phe Asn Arg Ala Asp Ala Ala Val Trp Thr Leu 
            20                  25                  30          


Ser Asp Arg Gln Gly Ile Thr Lys Ser Ala Pro Leu Arg Val Ser Gln 
        35                  40                  45              


Leu Phe Ser Arg Ser Cys Pro Arg Val Leu Pro Arg Gln Pro Ser Thr 
    50                  55                  60                  


Ala Met Ala Ala Tyr Gly Gln Thr Gln Tyr Ser Ala Gly Ile Gln Gln 
65                  70                  75                  80  


Ala Thr Pro Tyr Thr Ala Tyr Pro Pro Pro Ala Gln Ala Tyr Gly Ile 
                85                  90                  95      


Pro Ser Tyr Ser Ile Lys Thr Glu Asp Ser Leu Asn His Ser Pro Gly 
            100                 105                 110         


Gln Ser Gly Phe Leu Ser Tyr Gly Ser Ser Phe Ser Thr Ser Pro Thr 
        115                 120                 125             


Gly Gln Ser Pro Tyr Thr Tyr Gln Met His Gly Thr Thr Gly Phe Tyr 
    130                 135                 140                 


Gln Gly Gly Asn Gly Leu Gly Asn Ala Ala Gly Phe Gly Ser Val His 
145                 150                 155                 160 


Gln Asp Tyr Pro Ser Tyr Pro Gly Phe Pro Gln Ser Gln Tyr Pro Gln 
                165                 170                 175     


Tyr Tyr Gly Ser Ser Tyr Asn Pro Pro Tyr Val Pro Ala Ser Ser Ile 
            180                 185                 190         


Cys Pro Ser Pro Leu Ser Thr Ser Thr Tyr Val Leu Gln Glu Ala Ser 
        195                 200                 205             


His Asn Val Pro Asn Gln Ser Ser Glu Ser Leu Ala Gly Glu Tyr Asn 
    210                 215                 220                 


Thr His Asn Gly Pro Ser Thr Pro Ala Lys Glu Gly Asp Thr Asp Arg 
225                 230                 235                 240 


Pro His Arg Ala Ser Asp Gly Lys Leu Arg Gly Arg Ser Lys Arg Ser 
                245                 250                 255     


Ser Asp Pro Ser Pro Ala Gly Asp Asn Glu Ile Glu Arg Val Phe Val 
            260                 265                 270         


Trp Asp Leu Asp Glu Thr Ile Ile Ile Phe His Ser Leu Leu Thr Gly 
        275                 280                 285             


Thr Phe Ala Ser Arg Tyr Gly Lys Asp Thr Thr Thr Ser Val Arg Ile 
    290                 295                 300                 


Gly Leu Met Met Glu Glu Met Ile Phe Asn Leu Ala Asp Thr His Leu 
305                 310                 315                 320 


Phe Phe Asn Asp Leu Glu Asp Cys Asp Gln Ile His Val Asp Asp Val 
                325                 330                 335     


Ser Ser Asp Asp Asn Gly Gln Asp Leu Ser Thr Tyr Asn Phe Ser Ala 
            340                 345                 350         


Asp Gly Phe His Ser Ser Ala Pro Gly Ala Asn Leu Cys Leu Gly Ser 
        355                 360                 365             


Gly Val His Gly Gly Val Asp Trp Met Arg Lys Leu Ala Phe Arg Tyr 
    370                 375                 380                 


Arg Arg Val Lys Glu Met Tyr Asn Thr Tyr Lys Asn Asn Val Gly Gly 
385                 390                 395                 400 


Leu Ile Gly Thr Pro Lys Arg Glu Thr Trp Leu Gln Leu Arg Ala Glu 
                405                 410                 415     


Leu Glu Ala Leu Thr Asp Leu Trp Leu Thr His Ser Leu Lys Ala Leu 
            420                 425                 430         


Asn Leu Ile Asn Ser Arg Pro Asn Cys Val Asn Val Leu Val Thr Thr 
        435                 440                 445             


Thr Gln Leu Ile Pro Ala Leu Ala Lys Val Leu Leu Tyr Gly Leu Gly 
    450                 455                 460                 


Ser Val Phe Pro Ile Glu Asn Ile Tyr Ser Ala Thr Lys Thr Gly Lys 
465                 470                 475                 480 


Glu Ser Cys Phe Glu Arg Ile Met Gln Arg Phe Gly Arg Lys Ala Val 
                485                 490                 495     


Tyr Val Val Ile Gly Asp Gly Val Glu Glu Glu Gln Gly Ala Lys Lys 
            500                 505                 510         


His Asn Met Pro Phe Trp Arg Ile Ser Cys His Ala Asp Leu Glu Ala 
        515                 520                 525             


Leu Arg His Ala Leu Glu Leu Glu Tyr Leu 
    530                 535             


<210>  3938
<211>  250
<212>  PRT
<213>  homo sapiens

<400>  3938

Met Lys Ala Thr Ile Ile Leu Leu Leu Leu Ala Gln Val Ser Trp Ala 
1               5                   10                  15      


Gly Pro Phe Gln Gln Arg Gly Leu Phe Asp Phe Met Leu Glu Asp Glu 
            20                  25                  30          


Ala Ser Gly Ile Gly Pro Glu Val Pro Asp Asp Arg Asp Phe Glu Pro 
        35                  40                  45              


Ser Leu Gly Pro Val Cys Pro Phe Arg Cys Gln Cys His Leu Arg Val 
    50                  55                  60                  


Val Gln Cys Ser Asp Leu Glu Leu Gly Thr Asn Pro Leu Lys Ser Ser 
65                  70                  75                  80  


Gly Ile Glu Asn Gly Ala Phe Gln Gly Met Lys Lys Leu Ser Tyr Ile 
                85                  90                  95      


Arg Ile Ala Asp Thr Asn Ile Thr Ser Ile Pro Gln Gly Leu Pro Pro 
            100                 105                 110         


Ser Leu Thr Glu Leu His Leu Asp Gly Asn Lys Ile Ser Arg Val Asp 
        115                 120                 125             


Ala Ala Ser Leu Lys Gly Leu Asn Asn Leu Ala Lys Leu Gly Leu Ser 
    130                 135                 140                 


Phe Asn Ser Ile Ser Ala Val Asp Asn Gly Ser Leu Ala Asn Thr Pro 
145                 150                 155                 160 


His Leu Arg Glu Leu His Leu Asp Asn Asn Lys Leu Thr Arg Val Pro 
                165                 170                 175     


Gly Gly Leu Ala Glu His Lys Tyr Ile Gln Val Val Tyr Leu His Asn 
            180                 185                 190         


Asn Asn Ile Ser Val Val Gly Ser Ser Asp Phe Cys Pro Pro Gly His 
        195                 200                 205             


Asn Thr Lys Lys Ala Ser Tyr Ser Gly Val Ser Leu Phe Ser Asn Pro 
    210                 215                 220                 


Val Gln Tyr Trp Glu Ile Gln Pro Ser Thr Phe Arg Cys Val Tyr Val 
225                 230                 235                 240 


Arg Ser Ala Ile Gln Leu Gly Asn Tyr Lys 
                245                 250 


<210>  3939
<211>  863
<212>  PRT
<213>  homo sapiens

<400>  3939

Met Ser Ser Pro Ala Ser Thr Pro Ser Arg Arg Gly Ser Arg Arg Gly 
1               5                   10                  15      


Arg Ala Thr Pro Ala Gln Thr Pro Arg Ser Glu Asp Ala Arg Ser Ser 
            20                  25                  30          


Pro Ser Gln Arg Arg Arg Gly Glu Asp Ser Thr Ser Thr Gly Glu Leu 
        35                  40                  45              


Gln Pro Met Pro Thr Ser Pro Gly Val Asp Leu Gln Ser Pro Ala Ala 
    50                  55                  60                  


Gln Asp Val Leu Phe Ser Ser Pro Pro Gln Met His Ser Ser Ala Ile 
65                  70                  75                  80  


Pro Leu Asp Phe Asp Val Ser Ser Pro Leu Thr Tyr Gly Thr Pro Ser 
                85                  90                  95      


Ser Arg Val Glu Gly Thr Pro Arg Ser Gly Val Arg Gly Thr Pro Val 
            100                 105                 110         


Arg Gln Arg Pro Asp Leu Gly Ser Ala Gln Lys Gly Leu Gln Val Asp 
        115                 120                 125             


Leu Gln Ser Asp Gly Ala Ala Ala Glu Asp Ile Val Ala Ser Glu Gln 
    130                 135                 140                 


Ser Leu Gly Gln Lys Leu Val Ile Trp Gly Thr Asp Val Asn Val Ala 
145                 150                 155                 160 


Ala Cys Lys Glu Asn Phe Gln Arg Phe Leu Gln Arg Phe Ile Asp Pro 
                165                 170                 175     


Leu Ala Lys Glu Glu Glu Asn Val Gly Ile Asp Ile Thr Glu Pro Leu 
            180                 185                 190         


Tyr Met Gln Arg Leu Gly Glu Ile Asn Val Ile Gly Glu Pro Phe Leu 
        195                 200                 205             


Asn Val Asn Cys Glu His Ile Lys Ser Phe Asp Lys Asn Leu Tyr Arg 
    210                 215                 220                 


Gln Leu Ile Ser Tyr Pro Gln Glu Val Ile Pro Thr Phe Asp Met Ala 
225                 230                 235                 240 


Val Asn Glu Ile Phe Phe Asp Arg Tyr Pro Asp Ser Ile Leu Glu His 
                245                 250                 255     


Gln Ile Gln Val Arg Pro Phe Asn Ala Leu Lys Thr Lys Asn Met Arg 
            260                 265                 270         


Asn Leu Asn Pro Glu Asp Ile Asp Gln Leu Ile Thr Ile Ser Gly Met 
        275                 280                 285             


Val Ile Arg Thr Ser Gln Leu Ile Pro Glu Met Gln Glu Ala Phe Phe 
    290                 295                 300                 


Gln Cys Gln Val Cys Ala His Thr Thr Arg Val Glu Met Asp Arg Gly 
305                 310                 315                 320 


Arg Ile Ala Glu Pro Ser Val Cys Gly Arg Cys His Thr Thr His Ser 
                325                 330                 335     


Met Ala Leu Ile His Asn Arg Ser Leu Phe Ser Asp Lys Gln Met Ile 
            340                 345                 350         


Lys Leu Gln Glu Ser Pro Glu Asp Met Pro Ala Gly Gln Thr Pro His 
        355                 360                 365             


Thr Val Ile Leu Phe Ala His Asn Asp Leu Val Asp Lys Val Gln Pro 
    370                 375                 380                 


Gly Asp Arg Val Asn Val Thr Gly Ile Tyr Arg Ala Val Pro Ile Arg 
385                 390                 395                 400 


Val Asn Pro Arg Val Ser Asn Val Lys Ser Val Tyr Lys Thr His Ile 
                405                 410                 415     


Asp Val Ile His Tyr Arg Lys Thr Asp Ala Lys Arg Leu His Gly Leu 
            420                 425                 430         


Asp Glu Glu Ala Glu Gln Lys Leu Phe Ser Glu Lys Arg Val Glu Leu 
        435                 440                 445             


Leu Lys Glu Leu Ser Arg Lys Pro Asp Ile Tyr Glu Arg Leu Ala Ser 
    450                 455                 460                 


Ala Leu Ala Pro Ser Ile Tyr Glu His Glu Asp Ile Lys Lys Gly Ile 
465                 470                 475                 480 


Leu Leu Gln Leu Phe Gly Gly Thr Arg Lys Asp Phe Ser His Thr Gly 
                485                 490                 495     


Arg Gly Lys Phe Arg Ala Glu Ile Asn Ile Leu Leu Cys Gly Asp Pro 
            500                 505                 510         


Gly Thr Ser Lys Ser Gln Leu Leu Gln Tyr Val Tyr Asn Leu Val Pro 
        515                 520                 525             


Arg Gly Gln Tyr Thr Ser Gly Lys Gly Ser Ser Ala Val Gly Leu Thr 
    530                 535                 540                 


Ala Tyr Val Met Lys Asp Pro Glu Thr Arg Gln Leu Val Leu Gln Thr 
545                 550                 555                 560 


Gly Ala Leu Val Leu Ser Asp Asn Gly Ile Cys Cys Ile Asp Glu Phe 
                565                 570                 575     


Asp Lys Met Asn Glu Ser Thr Arg Ser Val Leu His Glu Val Met Glu 
            580                 585                 590         


Gln Gln Thr Leu Ser Ile Ala Lys Ala Gly Ile Ile Cys Gln Leu Asn 
        595                 600                 605             


Ala Arg Thr Ser Val Leu Ala Ala Ala Asn Pro Ile Glu Ser Gln Trp 
    610                 615                 620                 


Asn Pro Lys Lys Thr Thr Ile Glu Asn Ile Gln Leu Pro His Thr Leu 
625                 630                 635                 640 


Leu Ser Arg Phe Asp Leu Ile Phe Leu Leu Leu Asp Pro Gln Asp Glu 
                645                 650                 655     


Ala Tyr Asp Arg Arg Leu Ala His His Leu Val Ala Leu Tyr Tyr Gln 
            660                 665                 670         


Ser Glu Glu Gln Ala Glu Glu Glu Leu Leu Asp Met Ala Val Leu Lys 
        675                 680                 685             


Asp Tyr Ile Ala Tyr Ala His Ser Thr Ile Met Pro Arg Leu Ser Glu 
    690                 695                 700                 


Glu Ala Ser Gln Ala Leu Ile Glu Ala Tyr Val Asp Met Arg Lys Ile 
705                 710                 715                 720 


Gly Ser Ser Arg Gly Met Val Ser Ala Tyr Pro Arg Gln Leu Glu Ser 
                725                 730                 735     


Leu Ile Arg Leu Ala Glu Ala His Ala Lys Val Arg Leu Ser Asn Lys 
            740                 745                 750         


Val Glu Ala Ile Asp Val Glu Glu Ala Lys Arg Leu His Arg Glu Ala 
        755                 760                 765             


Leu Lys Gln Ser Ala Thr Asp Pro Arg Thr Gly Ile Val Asp Ile Ser 
    770                 775                 780                 


Ile Leu Thr Thr Gly Met Ser Ala Thr Ser Arg Lys Arg Lys Glu Glu 
785                 790                 795                 800 


Leu Ala Glu Ala Leu Lys Lys Leu Ile Leu Ser Lys Gly Lys Thr Pro 
                805                 810                 815     


Ala Leu Lys Tyr Gln Gln Leu Phe Glu Asp Ile Arg Gly Gln Ser Asp 
            820                 825                 830         


Ile Ala Ile Thr Lys Asp Met Phe Glu Glu Ala Leu Arg Ala Leu Ala 
        835                 840                 845             


Asp Asp Asp Phe Leu Thr Val Thr Gly Lys Thr Val Arg Leu Leu 
    850                 855                 860             


<210>  3940
<211>  150
<212>  PRT
<213>  homo sapiens

<400>  3940

Met Ser Lys Ile Ser Gln Gln Asn Ser Thr Pro Gly Val Asn Gly Ile 
1               5                   10                  15      


Ser Val Ile His Thr Gln Ala His Ala Ser Gly Leu Gln Gln Val Pro 
            20                  25                  30          


Gln Leu Val Pro Ala Gly Pro Gly Gly Gly Gly Lys Ala Val Ala Pro 
        35                  40                  45              


Ser Lys Gln Ser Lys Lys Ser Ser Pro Met Asp Arg Asn Ser Asp Glu 
    50                  55                  60                  


Tyr Arg Gln Arg Arg Glu Arg Asn Asn Met Ala Val Lys Lys Ser Arg 
65                  70                  75                  80  


Leu Lys Ser Lys Gln Lys Ala Gln Asp Thr Leu Gln Arg Val Asn Gln 
                85                  90                  95      


Leu Lys Glu Glu Asn Glu Arg Leu Glu Ala Lys Ile Lys Leu Leu Thr 
            100                 105                 110         


Lys Glu Leu Ser Val Leu Lys Asp Leu Phe Leu Glu His Ala His Asn 
        115                 120                 125             


Leu Ala Asp Asn Val Gln Ser Ile Ser Thr Glu Asn Thr Thr Ala Asp 
    130                 135                 140                 


Gly Asp Asn Ala Gly Gln 
145                 150 


<210>  3941
<211>  555
<212>  PRT
<213>  homo sapiens

<400>  3941

Met Pro Ser Trp Ile Gly Ala Val Ile Leu Pro Leu Leu Gly Leu Leu 
1               5                   10                  15      


Leu Ser Leu Pro Ala Gly Ala Asp Val Lys Ala Arg Ser Cys Gly Glu 
            20                  25                  30          


Val Arg Gln Ala Tyr Gly Ala Lys Gly Phe Ser Leu Ala Asp Ile Pro 
        35                  40                  45              


Tyr Gln Glu Ile Ala Gly Glu His Leu Arg Ile Cys Pro Gln Glu Tyr 
    50                  55                  60                  


Thr Cys Cys Thr Thr Glu Met Glu Asp Lys Leu Ser Gln Gln Ser Lys 
65                  70                  75                  80  


Leu Glu Phe Glu Asn Leu Val Glu Glu Thr Ser His Phe Val Arg Thr 
                85                  90                  95      


Thr Phe Val Ser Arg His Lys Lys Phe Asp Glu Phe Phe Arg Glu Leu 
            100                 105                 110         


Leu Glu Asn Ala Glu Lys Ser Leu Asn Asp Met Phe Val Arg Thr Tyr 
        115                 120                 125             


Gly Met Leu Tyr Met Gln Asn Ser Glu Val Phe Gln Asp Leu Phe Thr 
    130                 135                 140                 


Glu Leu Lys Arg Tyr Tyr Thr Gly Gly Asn Val Asn Leu Glu Glu Met 
145                 150                 155                 160 


Leu Asn Asp Phe Trp Ala Arg Leu Leu Glu Arg Met Phe Gln Leu Ile 
                165                 170                 175     


Asn Pro Gln Tyr His Phe Ser Glu Asp Tyr Leu Glu Cys Val Ser Lys 
            180                 185                 190         


Tyr Thr Asp Gln Leu Lys Pro Phe Gly Asp Val Pro Arg Lys Leu Lys 
        195                 200                 205             


Ile Gln Val Thr Arg Ala Phe Ile Ala Ala Arg Thr Phe Val Gln Gly 
    210                 215                 220                 


Leu Thr Val Gly Arg Glu Val Ala Asn Arg Val Ser Lys Val Ser Pro 
225                 230                 235                 240 


Thr Pro Gly Cys Ile Arg Ala Leu Met Lys Met Leu Tyr Cys Pro Tyr 
                245                 250                 255     


Cys Arg Gly Leu Pro Thr Val Arg Pro Cys Asn Asn Tyr Cys Leu Asn 
            260                 265                 270         


Val Met Lys Gly Cys Leu Ala Asn Gln Ala Asp Leu Asp Thr Glu Trp 
        275                 280                 285             


Asn Leu Phe Ile Asp Ala Met Leu Leu Val Ala Glu Arg Leu Glu Gly 
    290                 295                 300                 


Pro Phe Asn Ile Glu Ser Val Met Asp Pro Ile Asp Val Lys Ile Ser 
305                 310                 315                 320 


Glu Ala Ile Met Asn Met Gln Glu Asn Ser Met Gln Val Ser Ala Lys 
                325                 330                 335     


Val Phe Gln Gly Cys Gly Gln Pro Lys Pro Ala Pro Ala Leu Arg Ser 
            340                 345                 350         


Ala Arg Ser Ala Pro Glu Asn Phe Asn Thr Arg Phe Arg Pro Tyr Asn 
        355                 360                 365             


Pro Glu Glu Arg Pro Thr Thr Ala Ala Gly Thr Ser Leu Asp Arg Leu 
    370                 375                 380                 


Val Thr Asp Ile Lys Glu Lys Leu Lys Leu Ser Lys Lys Val Trp Ser 
385                 390                 395                 400 


Ala Leu Pro Tyr Thr Ile Cys Lys Asp Glu Ser Val Thr Ala Gly Thr 
                405                 410                 415     


Ser Asn Glu Glu Glu Cys Trp Asn Gly His Ser Lys Ala Arg Tyr Leu 
            420                 425                 430         


Pro Glu Ile Met Asn Asp Gly Leu Thr Asn Gln Ile Asn Asn Pro Glu 
        435                 440                 445             


Val Asp Val Asp Ile Thr Arg Pro Asp Thr Phe Ile Arg Gln Gln Ile 
    450                 455                 460                 


Met Ala Leu Arg Val Met Thr Asn Lys Leu Lys Asn Ala Tyr Asn Gly 
465                 470                 475                 480 


Asn Asp Val Asn Phe Gln Asp Thr Ser Asp Glu Ser Ser Gly Ser Gly 
                485                 490                 495     


Ser Gly Ser Gly Cys Met Asp Asp Val Cys Pro Thr Glu Phe Glu Phe 
            500                 505                 510         


Val Thr Thr Glu Ala Pro Ala Val Asp Pro Asp Arg Arg Glu Val Asp 
        515                 520                 525             


Ser Ser Ala Ala Gln Arg Gly His Ser Leu Leu Ser Trp Ser Leu Thr 
    530                 535                 540                 


Cys Ile Val Leu Ala Leu Gln Arg Leu Cys Arg 
545                 550                 555 


<210>  3942
<211>  727
<212>  PRT
<213>  homo sapiens

<400>  3942

Met Ala Phe Gln Lys Ala Val Lys Gly Thr Ile Leu Val Gly Gly Gly 
1               5                   10                  15      


Ala Leu Ala Thr Val Leu Gly Leu Ser Gln Phe Ala His Tyr Arg Arg 
            20                  25                  30          


Lys Gln Met Asn Leu Ala Tyr Val Lys Ala Ala Asp Cys Ile Ser Glu 
        35                  40                  45              


Pro Val Asn Arg Glu Pro Pro Ser Arg Glu Ala Gln Leu Leu Thr Leu 
    50                  55                  60                  


Gln Asn Thr Ser Glu Phe Asp Ile Leu Val Ile Gly Gly Gly Ala Thr 
65                  70                  75                  80  


Gly Ser Gly Cys Ala Leu Asp Ala Val Thr Arg Gly Leu Lys Thr Ala 
                85                  90                  95      


Leu Val Glu Arg Asp Asp Phe Ser Ser Gly Thr Ser Ser Arg Ser Thr 
            100                 105                 110         


Lys Leu Ile His Gly Gly Val Arg Tyr Leu Gln Lys Ala Ile Met Lys 
        115                 120                 125             


Leu Asp Ile Glu Gln Tyr Arg Met Val Lys Glu Ala Leu His Glu Arg 
    130                 135                 140                 


Ala Asn Leu Leu Glu Ile Ala Pro His Leu Ser Ala Pro Leu Pro Ile 
145                 150                 155                 160 


Met Leu Pro Val Tyr Lys Trp Trp Gln Leu Pro Tyr Tyr Trp Val Gly 
                165                 170                 175     


Ile Lys Leu Tyr Asp Leu Val Ala Gly Ser Asn Cys Leu Lys Ser Ser 
            180                 185                 190         


Tyr Val Leu Ser Lys Ser Arg Ala Leu Glu His Phe Pro Met Leu Gln 
        195                 200                 205             


Lys Asp Lys Leu Val Gly Ala Ile Val Tyr Tyr Asp Gly Gln His Asn 
    210                 215                 220                 


Asp Ala Arg Met Asn Leu Ala Ile Ala Leu Thr Ala Ala Arg Tyr Gly 
225                 230                 235                 240 


Ala Ala Thr Ala Asn Tyr Met Glu Val Val Ser Leu Leu Lys Lys Thr 
                245                 250                 255     


Asp Pro Gln Thr Gly Lys Val Arg Val Ser Gly Ala Arg Cys Lys Asp 
            260                 265                 270         


Val Leu Thr Gly Gln Glu Phe Asp Val Arg Ala Lys Cys Val Ile Asn 
        275                 280                 285             


Ala Thr Gly Pro Phe Thr Asp Ser Val Arg Lys Met Asp Asp Lys Asp 
    290                 295                 300                 


Ala Ala Ala Ile Cys Gln Pro Ser Ala Gly Val His Ile Val Met Pro 
305                 310                 315                 320 


Gly Tyr Tyr Ser Pro Glu Ser Met Gly Leu Leu Asp Pro Ala Thr Ser 
                325                 330                 335     


Asp Gly Arg Val Ile Phe Phe Leu Pro Trp Gln Lys Met Thr Ile Ala 
            340                 345                 350         


Gly Thr Thr Asp Thr Pro Thr Asp Val Thr His His Pro Ile Pro Ser 
        355                 360                 365             


Glu Glu Asp Ile Asn Phe Ile Leu Asn Glu Val Arg Asn Tyr Leu Ser 
    370                 375                 380                 


Cys Asp Val Glu Val Arg Arg Gly Asp Val Leu Ala Ala Trp Ser Gly 
385                 390                 395                 400 


Ile Arg Pro Leu Val Thr Asp Pro Lys Ser Ala Asp Thr Gln Ser Ile 
                405                 410                 415     


Ser Arg Asn His Val Val Asp Ile Ser Glu Ser Gly Leu Ile Thr Ile 
            420                 425                 430         


Ala Gly Gly Lys Trp Thr Thr Tyr Arg Ser Met Ala Glu Asp Thr Ile 
        435                 440                 445             


Asn Ala Ala Val Lys Thr His Asn Leu Lys Ala Gly Pro Ser Arg Thr 
    450                 455                 460                 


Val Gly Leu Phe Leu Gln Gly Gly Lys Asp Trp Ser Pro Thr Leu Tyr 
465                 470                 475                 480 


Ile Arg Leu Val Gln Asp Tyr Gly Leu Glu Ser Glu Val Ala Gln His 
                485                 490                 495     


Leu Ala Ala Thr Tyr Gly Asp Lys Ala Phe Glu Val Ala Lys Met Ala 
            500                 505                 510         


Ser Val Thr Gly Lys Arg Trp Pro Ile Val Gly Val Arg Leu Val Ser 
        515                 520                 525             


Glu Phe Pro Tyr Ile Glu Ala Glu Val Lys Tyr Gly Ile Lys Glu Tyr 
    530                 535                 540                 


Ala Cys Thr Ala Val Asp Met Ile Ser Arg Arg Thr Arg Leu Ala Phe 
545                 550                 555                 560 


Leu Asn Val Gln Ala Ala Glu Glu Ala Leu Pro Arg Ile Val Glu Leu 
                565                 570                 575     


Met Gly Arg Glu Leu Asn Trp Asp Asp Tyr Lys Lys Gln Glu Gln Leu 
            580                 585                 590         


Glu Thr Ala Arg Lys Phe Leu Tyr Tyr Glu Met Gly Tyr Lys Ser Arg 
        595                 600                 605             


Ser Glu Gln Leu Thr Asp Arg Ser Glu Ile Ser Leu Leu Pro Ser Asp 
    610                 615                 620                 


Ile Asp Arg Tyr Lys Lys Arg Phe His Lys Phe Asp Ala Asp Gln Lys 
625                 630                 635                 640 


Gly Phe Ile Thr Ile Val Asp Val Gln Arg Val Leu Glu Ser Ile Asn 
                645                 650                 655     


Val Gln Met Asp Glu Asn Thr Leu His Glu Ile Leu Asn Glu Val Asp 
            660                 665                 670         


Leu Asn Lys Asn Gly Gln Val Glu Leu Asn Glu Phe Leu Gln Leu Met 
        675                 680                 685             


Ser Ala Ile Gln Lys Gly Arg Val Ser Gly Ser Arg Leu Ala Ile Leu 
    690                 695                 700                 


Met Lys Thr Ala Glu Glu Asn Leu Asp Arg Arg Val Pro Ile Pro Val 
705                 710                 715                 720 


Asp Arg Ser Cys Gly Gly Leu 
                725         


<210>  3943
<211>  1140
<212>  PRT
<213>  homo sapiens

<400>  3943

Met Val Ile Ser Leu Asn Ser Cys Leu Ser Phe Ile Cys Leu Leu Leu 
1               5                   10                  15      


Cys His Trp Ile Gly Thr Ala Ser Pro Leu Asn Leu Glu Asp Pro Asn 
            20                  25                  30          


Val Cys Ser His Trp Glu Ser Tyr Ser Val Thr Val Gln Glu Ser Tyr 
        35                  40                  45              


Pro His Pro Phe Asp Gln Ile Tyr Tyr Thr Ser Cys Thr Asp Ile Leu 
    50                  55                  60                  


Asn Trp Phe Lys Cys Thr Arg His Arg Val Ser Tyr Arg Thr Ala Tyr 
65                  70                  75                  80  


Arg His Gly Glu Lys Thr Met Tyr Arg Arg Lys Ser Gln Cys Cys Pro 
                85                  90                  95      


Gly Phe Tyr Glu Ser Gly Glu Met Cys Val Pro His Cys Ala Asp Lys 
            100                 105                 110         


Cys Val His Gly Arg Cys Ile Ala Pro Asn Thr Cys Gln Cys Glu Pro 
        115                 120                 125             


Gly Trp Gly Gly Thr Asn Cys Ser Ser Ala Cys Asp Gly Asp His Trp 
    130                 135                 140                 


Gly Pro His Cys Thr Ser Arg Cys Gln Cys Lys Asn Gly Ala Leu Cys 
145                 150                 155                 160 


Asn Pro Ile Thr Gly Ala Cys His Cys Ala Ala Gly Phe Arg Gly Trp 
                165                 170                 175     


Arg Cys Glu Asp Arg Cys Glu Gln Gly Thr Tyr Gly Asn Asp Cys His 
            180                 185                 190         


Gln Arg Cys Gln Cys Gln Asn Gly Ala Thr Cys Asp His Val Thr Gly 
        195                 200                 205             


Glu Cys Arg Cys Pro Pro Gly Tyr Thr Gly Ala Phe Cys Glu Asp Leu 
    210                 215                 220                 


Cys Pro Pro Gly Lys His Gly Pro Gln Cys Glu Gln Arg Cys Pro Cys 
225                 230                 235                 240 


Gln Asn Gly Gly Val Cys His His Val Thr Gly Glu Cys Ser Cys Pro 
                245                 250                 255     


Ser Gly Trp Met Gly Thr Val Cys Gly Gln Pro Cys Pro Glu Gly Arg 
            260                 265                 270         


Phe Gly Lys Asn Cys Ser Gln Glu Cys Gln Cys His Asn Gly Gly Thr 
        275                 280                 285             


Cys Asp Ala Ala Thr Gly Gln Cys His Cys Ser Pro Gly Tyr Thr Gly 
    290                 295                 300                 


Glu Arg Cys Gln Asp Glu Cys Pro Val Gly Thr Tyr Gly Val Leu Cys 
305                 310                 315                 320 


Ala Glu Thr Cys Gln Cys Val Asn Gly Gly Lys Cys Tyr His Val Ser 
                325                 330                 335     


Gly Ala Cys Leu Cys Glu Ala Gly Phe Ala Gly Glu Arg Cys Glu Ala 
            340                 345                 350         


Arg Leu Cys Pro Glu Gly Leu Tyr Gly Ile Lys Cys Asp Lys Arg Cys 
        355                 360                 365             


Pro Cys His Leu Glu Asn Thr His Ser Cys His Pro Met Ser Gly Glu 
    370                 375                 380                 


Cys Ala Cys Lys Pro Gly Trp Ser Gly Leu Tyr Cys Asn Glu Thr Cys 
385                 390                 395                 400 


Ser Pro Gly Phe Tyr Gly Glu Ala Cys Gln Gln Ile Cys Ser Cys Gln 
                405                 410                 415     


Asn Gly Ala Asp Cys Asp Ser Val Thr Gly Lys Cys Thr Cys Ala Pro 
            420                 425                 430         


Gly Phe Lys Gly Ile Asp Cys Ser Thr Pro Cys Pro Leu Gly Thr Tyr 
        435                 440                 445             


Gly Ile Asn Cys Ser Ser Arg Cys Gly Cys Lys Asn Asp Ala Val Cys 
    450                 455                 460                 


Ser Pro Val Asp Gly Ser Cys Thr Cys Lys Ala Gly Trp His Gly Val 
465                 470                 475                 480 


Asp Cys Ser Ile Arg Cys Pro Ser Gly Thr Trp Gly Phe Gly Cys Asn 
                485                 490                 495     


Leu Thr Cys Gln Cys Leu Asn Gly Gly Ala Cys Asn Thr Leu Asp Gly 
            500                 505                 510         


Thr Cys Thr Cys Ala Pro Gly Trp Arg Gly Glu Lys Cys Glu Leu Pro 
        515                 520                 525             


Cys Gln Asp Gly Thr Tyr Gly Leu Asn Cys Ala Glu Arg Cys Asp Cys 
    530                 535                 540                 


Ser His Ala Asp Gly Cys His Pro Thr Thr Gly His Cys Arg Cys Leu 
545                 550                 555                 560 


Pro Gly Trp Ser Gly Val His Cys Asp Ser Val Cys Ala Glu Gly Arg 
                565                 570                 575     


Trp Gly Pro Asn Cys Ser Leu Pro Cys Tyr Cys Lys Asn Gly Ala Ser 
            580                 585                 590         


Cys Ser Pro Asp Asp Gly Ile Cys Glu Cys Ala Pro Gly Phe Arg Gly 
        595                 600                 605             


Thr Thr Cys Gln Arg Ile Cys Ser Pro Gly Phe Tyr Gly His Arg Cys 
    610                 615                 620                 


Ser Gln Thr Cys Pro Gln Cys Val His Ser Ser Gly Pro Cys His His 
625                 630                 635                 640 


Ile Thr Gly Leu Cys Asp Cys Leu Pro Gly Phe Thr Gly Ala Leu Cys 
                645                 650                 655     


Asn Glu Val Cys Pro Ser Gly Arg Phe Gly Lys Asn Cys Ala Gly Ile 
            660                 665                 670         


Cys Thr Cys Thr Asn Asn Gly Thr Cys Asn Pro Ile Asp Arg Ser Cys 
        675                 680                 685             


Gln Cys Tyr Pro Gly Trp Ile Gly Ser Asp Cys Ser Gln Pro Cys Pro 
    690                 695                 700                 


Pro Ala His Trp Gly Pro Asn Cys Ile His Thr Cys Asn Cys His Asn 
705                 710                 715                 720 


Gly Ala Phe Cys Ser Ala Tyr Asp Gly Glu Cys Lys Cys Thr Pro Gly 
                725                 730                 735     


Trp Thr Gly Leu Tyr Cys Thr Gln Arg Cys Pro Leu Gly Phe Tyr Gly 
            740                 745                 750         


Lys Asp Cys Ala Leu Ile Cys Gln Cys Gln Asn Gly Ala Asp Cys Asp 
        755                 760                 765             


His Ile Ser Gly Gln Cys Thr Cys Arg Thr Gly Phe Met Gly Arg His 
    770                 775                 780                 


Cys Glu Gln Lys Cys Pro Ser Gly Thr Tyr Gly Tyr Gly Cys Arg Gln 
785                 790                 795                 800 


Ile Cys Asp Cys Leu Asn Asn Ser Thr Cys Asp His Ile Thr Gly Thr 
                805                 810                 815     


Cys Tyr Cys Ser Pro Gly Trp Lys Gly Ala Arg Cys Asp Gln Ala Gly 
            820                 825                 830         


Val Ile Ile Val Gly Asn Leu Asn Ser Leu Ser Arg Thr Ser Thr Ala 
        835                 840                 845             


Leu Pro Ala Asp Ser Tyr Gln Ile Gly Ala Ile Ala Gly Ile Ile Ile 
    850                 855                 860                 


Leu Val Leu Val Val Leu Phe Leu Leu Ala Leu Phe Ile Ile Tyr Arg 
865                 870                 875                 880 


His Lys Gln Lys Gly Lys Glu Ser Ser Met Pro Ala Val Thr Tyr Thr 
                885                 890                 895     


Pro Ala Met Arg Val Val Asn Ala Asp Tyr Thr Ile Ser Gly Thr Leu 
            900                 905                 910         


Pro His Ser Asn Gly Gly Asn Ala Asn Ser His Tyr Phe Thr Asn Pro 
        915                 920                 925             


Ser Tyr His Thr Leu Thr Gln Cys Ala Thr Ser Pro His Val Asn Asn 
    930                 935                 940                 


Arg Asp Arg Met Thr Val Thr Lys Ser Lys Asn Asn Gln Leu Phe Val 
945                 950                 955                 960 


Asn Leu Lys Asn Val Asn Pro Gly Lys Arg Gly Pro Val Gly Asp Cys 
                965                 970                 975     


Thr Gly Thr Leu Pro Ala Asp Trp Lys His Gly Gly Tyr Leu Asn Glu 
            980                 985                 990         


Leu Gly Ala Phe Gly Leu Asp Arg  Ser Tyr Met Gly Lys  Ser Leu Lys 
        995                 1000                 1005             


Asp Leu  Gly Lys Asn Ser Glu  Tyr Asn Ser Ser Asn  Cys Ser Leu 
    1010                 1015                 1020             


Ser Ser  Ser Glu Asn Pro Tyr  Ala Thr Ile Lys Asp  Pro Pro Val 
    1025                 1030                 1035             


Leu Ile  Pro Lys Ser Ser Glu  Cys Gly Tyr Val Glu  Met Lys Ser 
    1040                 1045                 1050             


Pro Ala  Arg Arg Asp Ser Pro  Tyr Ala Glu Ile Asn  Asn Ser Thr 
    1055                 1060                 1065             


Ser Ala  Asn Arg Asn Val Tyr  Glu Val Glu Pro Thr  Val Ser Val 
    1070                 1075                 1080             


Val Gln  Gly Val Phe Ser Asn  Asn Gly Arg Leu Ser  Gln Asp Pro 
    1085                 1090                 1095             


Tyr Asp  Leu Pro Lys Asn Ser  His Ile Pro Cys His  Tyr Asp Leu 
    1100                 1105                 1110             


Leu Pro  Val Arg Asp Ser Ser  Ser Ser Pro Lys Gln  Glu Asp Ser 
    1115                 1120                 1125             


Gly Gly  Ser Ser Ser Asn Ser  Ser Ser Ser Ser Glu  
    1130                 1135                 1140 


<210>  3944
<211>  390
<212>  PRT
<213>  homo sapiens

<400>  3944

Met Ala Gln Arg Tyr Asp Asp Leu Pro His Tyr Gly Gly Met Asp Gly 
1               5                   10                  15      


Val Gly Ile Pro Ser Thr Met Tyr Gly Asp Pro His Ala Ala Arg Ser 
            20                  25                  30          


Met Gln Pro Val His His Leu Asn His Gly Pro Pro Leu His Ser His 
        35                  40                  45              


Gln Tyr Pro His Thr Ala His Thr Asn Ala Met Ala Pro Ser Met Gly 
    50                  55                  60                  


Ser Ser Val Asn Asp Ala Leu Lys Arg Asp Lys Asp Ala Ile Tyr Gly 
65                  70                  75                  80  


His Pro Leu Phe Pro Leu Leu Ala Leu Ile Phe Glu Lys Cys Glu Leu 
                85                  90                  95      


Ala Thr Cys Thr Pro Arg Glu Pro Gly Val Ala Gly Gly Asp Val Cys 
            100                 105                 110         


Ser Ser Glu Ser Phe Asn Glu Asp Ile Ala Val Phe Ala Lys Gln Ile 
        115                 120                 125             


Arg Ala Glu Lys Pro Leu Phe Ser Ser Asn Pro Glu Leu Asp Asn Leu 
    130                 135                 140                 


Met Ile Gln Ala Ile Gln Val Leu Arg Phe His Leu Leu Glu Leu Glu 
145                 150                 155                 160 


Lys Val His Glu Leu Cys Asp Asn Phe Cys His Arg Tyr Ile Ser Cys 
                165                 170                 175     


Leu Lys Gly Lys Met Pro Ile Asp Leu Val Ile Asp Asp Arg Glu Gly 
            180                 185                 190         


Gly Ser Lys Ser Asp Ser Glu Asp Ile Thr Arg Ser Ala Asn Leu Thr 
        195                 200                 205             


Asp Gln Pro Ser Trp Asn Arg Asp His Asp Asp Thr Ala Ser Thr Arg 
    210                 215                 220                 


Ser Gly Gly Thr Pro Gly Pro Ser Ser Gly Gly His Thr Ser His Ser 
225                 230                 235                 240 


Gly Asp Asn Ser Ser Glu Gln Gly Asp Gly Leu Asp Asn Ser Val Ala 
                245                 250                 255     


Ser Pro Ser Thr Gly Asp Asp Asp Asp Pro Asp Lys Asp Lys Lys Arg 
            260                 265                 270         


His Lys Lys Arg Gly Ile Phe Pro Lys Val Ala Thr Asn Ile Met Arg 
        275                 280                 285             


Ala Trp Leu Phe Gln His Leu Thr His Pro Tyr Pro Ser Glu Glu Gln 
    290                 295                 300                 


Lys Lys Gln Leu Ala Gln Asp Thr Gly Leu Thr Ile Leu Gln Val Asn 
305                 310                 315                 320 


Asn Trp Phe Ile Asn Ala Arg Arg Arg Ile Val Gln Pro Met Ile Asp 
                325                 330                 335     


Gln Ser Asn Arg Ala Val Ser Gln Gly Thr Pro Tyr Asn Pro Asp Gly 
            340                 345                 350         


Gln Pro Met Gly Gly Phe Val Met Asp Gly Gln Gln His Met Gly Ile 
        355                 360                 365             


Arg Ala Pro Gly Pro Met Ser Gly Met Gly Met Asn Met Gly Met Glu 
    370                 375                 380                 


Gly Gln Trp His Tyr Met 
385                 390 


<210>  3945
<211>  351
<212>  PRT
<213>  homo sapiens

<400>  3945

Met Thr Glu Met Ser Phe Leu Ser Ser Glu Val Leu Val Gly Asp Leu 
1               5                   10                  15      


Met Ser Pro Phe Asp Gln Ser Gly Leu Gly Ala Glu Glu Ser Leu Gly 
            20                  25                  30          


Leu Leu Asp Asp Tyr Leu Glu Val Ala Lys His Phe Lys Pro His Gly 
        35                  40                  45              


Phe Ser Ser Asp Lys Ala Lys Ala Gly Ser Ser Glu Trp Leu Ala Val 
    50                  55                  60                  


Asp Gly Leu Val Ser Pro Ser Asn Asn Ser Lys Glu Asp Ala Phe Ser 
65                  70                  75                  80  


Gly Thr Asp Trp Met Leu Glu Lys Met Asp Leu Lys Glu Phe Asp Leu 
                85                  90                  95      


Asp Ala Leu Leu Gly Ile Asp Asp Leu Glu Thr Met Pro Asp Asp Leu 
            100                 105                 110         


Leu Thr Thr Leu Asp Asp Thr Cys Asp Leu Phe Ala Pro Leu Val Gln 
        115                 120                 125             


Glu Thr Asn Lys Gln Pro Pro Gln Thr Val Asn Pro Ile Gly His Leu 
    130                 135                 140                 


Pro Glu Ser Leu Thr Lys Pro Asp Gln Val Ala Pro Phe Thr Phe Leu 
145                 150                 155                 160 


Gln Pro Leu Pro Leu Ser Pro Gly Val Leu Ser Ser Thr Pro Asp His 
                165                 170                 175     


Ser Phe Ser Leu Glu Leu Gly Ser Glu Val Asp Ile Thr Glu Gly Asp 
            180                 185                 190         


Arg Lys Pro Asp Tyr Thr Ala Tyr Val Ala Met Ile Pro Gln Cys Ile 
        195                 200                 205             


Lys Glu Glu Asp Thr Pro Ser Asp Asn Asp Ser Gly Ile Cys Met Ser 
    210                 215                 220                 


Pro Glu Ser Tyr Leu Gly Ser Pro Gln His Ser Pro Ser Thr Arg Gly 
225                 230                 235                 240 


Ser Pro Asn Arg Ser Leu Pro Ser Pro Gly Val Leu Cys Gly Ser Ala 
                245                 250                 255     


Arg Pro Lys Pro Tyr Asp Pro Pro Gly Glu Lys Met Val Ala Ala Lys 
            260                 265                 270         


Val Lys Gly Glu Lys Leu Asp Lys Lys Leu Lys Lys Met Glu Gln Asn 
        275                 280                 285             


Lys Thr Ala Ala Thr Arg Tyr Arg Gln Lys Lys Arg Ala Glu Gln Glu 
    290                 295                 300                 


Ala Leu Thr Gly Glu Cys Lys Glu Leu Glu Lys Lys Asn Glu Ala Leu 
305                 310                 315                 320 


Lys Glu Arg Ala Asp Ser Leu Ala Lys Glu Ile Gln Tyr Leu Lys Asp 
                325                 330                 335     


Leu Ile Glu Glu Val Arg Lys Ala Arg Gly Lys Lys Arg Val Pro 
            340                 345                 350     


<210>  3946
<211>  282
<212>  PRT
<213>  homo sapiens

<400>  3946

Met Ser Leu Leu Ala Thr Leu Gly Leu Glu Leu Asp Arg Ala Leu Leu 
1               5                   10                  15      


Pro Ala Ser Gly Leu Gly Trp Leu Val Asp Tyr Gly Lys Leu Pro Pro 
            20                  25                  30          


Ala Pro Ala Pro Leu Ala Pro Tyr Glu Val Leu Gly Gly Ala Leu Glu 
        35                  40                  45              


Gly Gly Leu Pro Val Gly Gly Glu Pro Leu Ala Gly Asp Gly Phe Ser 
    50                  55                  60                  


Asp Trp Met Thr Glu Arg Val Asp Phe Thr Ala Leu Leu Pro Leu Glu 
65                  70                  75                  80  


Pro Pro Leu Pro Pro Gly Thr Leu Pro Gln Pro Ser Pro Thr Pro Pro 
                85                  90                  95      


Asp Leu Glu Ala Met Ala Ser Leu Leu Lys Lys Glu Leu Glu Gln Met 
            100                 105                 110         


Glu Asp Phe Phe Leu Asp Ala Pro Pro Leu Pro Pro Pro Ser Pro Pro 
        115                 120                 125             


Pro Leu Pro Pro Pro Pro Leu Pro Pro Ala Pro Ser Leu Pro Leu Ser 
    130                 135                 140                 


Leu Pro Ser Phe Asp Leu Pro Gln Pro Pro Val Leu Asp Thr Leu Asp 
145                 150                 155                 160 


Leu Leu Ala Ile Tyr Cys Arg Asn Glu Ala Gly Gln Glu Glu Val Gly 
                165                 170                 175     


Met Pro Pro Leu Pro Pro Pro Gln Gln Pro Pro Pro Pro Ser Pro Pro 
            180                 185                 190         


Gln Pro Ser Arg Leu Ala Pro Tyr Pro His Pro Ala Thr Thr Arg Gly 
        195                 200                 205             


Asp Arg Lys Gln Lys Lys Arg Asp Gln Asn Lys Ser Ala Ala Leu Arg 
    210                 215                 220                 


Tyr Arg Gln Arg Lys Arg Ala Glu Gly Glu Ala Leu Glu Gly Glu Cys 
225                 230                 235                 240 


Gln Gly Leu Glu Ala Arg Asn Arg Glu Leu Lys Glu Arg Ala Glu Ser 
                245                 250                 255     


Val Glu Arg Glu Ile Gln Tyr Val Lys Asp Leu Leu Ile Glu Val Tyr 
            260                 265                 270         


Lys Ala Arg Ser Gln Arg Thr Arg Ser Cys 
        275                 280         


<210>  3947
<211>  555
<212>  PRT
<213>  homo sapiens

<400>  3947

Met Ser Thr Glu Thr Glu Leu Gln Val Ala Val Lys Thr Ser Ala Lys 
1               5                   10                  15      


Lys Asp Ser Arg Lys Lys Gly Gln Asp Arg Ser Glu Ala Thr Leu Ile 
            20                  25                  30          


Lys Arg Phe Lys Gly Glu Gly Val Arg Tyr Lys Ala Lys Leu Ile Gly 
        35                  40                  45              


Ile Asp Glu Val Ser Ala Ala Arg Gly Asp Lys Leu Cys Gln Asp Ser 
    50                  55                  60                  


Met Met Lys Leu Lys Gly Val Val Ala Gly Ala Arg Ser Lys Gly Glu 
65                  70                  75                  80  


His Lys Gln Lys Ile Phe Leu Thr Ile Ser Phe Gly Gly Ile Lys Ile 
                85                  90                  95      


Phe Asp Glu Lys Thr Gly Ala Leu Gln His His His Ala Val His Glu 
            100                 105                 110         


Ile Ser Tyr Ile Ala Lys Asp Ile Thr Asp His Arg Ala Phe Gly Tyr 
        115                 120                 125             


Val Cys Gly Lys Glu Gly Asn His Arg Phe Val Ala Ile Lys Thr Ala 
    130                 135                 140                 


Gln Ala Ala Glu Pro Val Ile Leu Asp Leu Arg Asp Leu Phe Gln Leu 
145                 150                 155                 160 


Ile Tyr Glu Leu Lys Gln Arg Glu Glu Leu Glu Lys Lys Ala Gln Lys 
                165                 170                 175     


Asp Lys Gln Cys Glu Gln Ala Val Tyr Gln Thr Ile Leu Glu Glu Asp 
            180                 185                 190         


Val Glu Asp Pro Val Tyr Gln Tyr Ile Val Phe Glu Ala Gly His Glu 
        195                 200                 205             


Pro Ile Arg Asp Pro Glu Thr Glu Glu Asn Ile Tyr Gln Val Pro Thr 
    210                 215                 220                 


Ser Gln Lys Lys Glu Gly Val Tyr Asp Val Pro Lys Ser Gln Pro Val 
225                 230                 235                 240 


Ser Ala Val Thr Gln Leu Glu Leu Phe Gly Asp Met Ser Thr Pro Pro 
                245                 250                 255     


Asp Ile Thr Ser Pro Pro Thr Pro Ala Thr Pro Gly Asp Ala Phe Ile 
            260                 265                 270         


Pro Ser Ser Ser Gln Thr Leu Pro Ala Ser Ala Asp Val Phe Ser Ser 
        275                 280                 285             


Val Pro Phe Gly Thr Ala Ala Val Pro Ser Gly Tyr Val Ala Met Gly 
    290                 295                 300                 


Ala Val Leu Pro Ser Phe Trp Gly Gln Gln Pro Leu Val Gln Gln Gln 
305                 310                 315                 320 


Met Val Met Gly Ala Gln Pro Pro Val Ala Gln Val Met Pro Gly Ala 
                325                 330                 335     


Gln Pro Ile Ala Trp Gly Gln Pro Gly Leu Phe Pro Ala Thr Gln Gln 
            340                 345                 350         


Pro Trp Pro Thr Val Ala Gly Gln Phe Pro Pro Ala Ala Phe Met Pro 
        355                 360                 365             


Thr Gln Thr Val Met Pro Leu Pro Ala Ala Met Phe Gln Gly Pro Leu 
    370                 375                 380                 


Thr Pro Leu Ala Thr Val Pro Gly Thr Ser Asp Ser Thr Arg Ser Ser 
385                 390                 395                 400 


Pro Gln Thr Asp Lys Pro Arg Gln Lys Met Gly Lys Glu Thr Phe Lys 
                405                 410                 415     


Asp Phe Gln Met Ala Gln Pro Pro Pro Val Pro Ser Arg Lys Pro Asp 
            420                 425                 430         


Gln Pro Ser Leu Thr Cys Thr Ser Glu Ala Phe Ser Ser Tyr Phe Asn 
        435                 440                 445             


Lys Val Gly Val Ala Gln Asp Thr Asp Asp Cys Asp Asp Phe Asp Ile 
    450                 455                 460                 


Ser Gln Leu Asn Leu Thr Pro Val Thr Ser Thr Thr Pro Ser Thr Asn 
465                 470                 475                 480 


Ser Pro Pro Thr Pro Ala Pro Arg Gln Ser Ser Pro Ser Lys Ser Ser 
                485                 490                 495     


Ala Ser His Ala Ser Asp Pro Thr Thr Asp Asp Ile Phe Glu Glu Gly 
            500                 505                 510         


Phe Glu Ser Pro Ser Lys Ser Glu Glu Gln Glu Ala Pro Asp Gly Ser 
        515                 520                 525             


Gln Ala Ser Ser Asn Ser Asp Pro Phe Gly Glu Pro Ser Gly Glu Pro 
    530                 535                 540                 


Ser Gly Asp Asn Ile Ser Pro Gln Ala Gly Ser 
545                 550                 555 


<210>  3948
<211>  1040
<212>  PRT
<213>  homo sapiens

<400>  3948

Met Gly Thr Ala Thr Arg Arg Lys Pro His Leu Leu Leu Val Ala Ala 
1               5                   10                  15      


Val Ala Leu Val Ser Ser Ser Ala Trp Ser Ser Ala Leu Gly Ser Gln 
            20                  25                  30          


Thr Thr Phe Gly Pro Val Phe Glu Asp Gln Pro Leu Ser Val Leu Phe 
        35                  40                  45              


Pro Glu Glu Ser Thr Glu Glu Gln Val Leu Leu Ala Cys Arg Ala Arg 
    50                  55                  60                  


Ala Ser Pro Pro Ala Thr Tyr Arg Trp Lys Met Asn Gly Thr Glu Met 
65                  70                  75                  80  


Lys Leu Glu Pro Gly Ser Arg His Gln Leu Val Gly Gly Asn Leu Val 
                85                  90                  95      


Ile Met Asn Pro Thr Lys Ala Gln Asp Ala Gly Val Tyr Gln Cys Leu 
            100                 105                 110         


Ala Ser Asn Pro Val Gly Thr Val Val Ser Arg Glu Ala Ile Leu Arg 
        115                 120                 125             


Phe Gly Phe Leu Gln Glu Phe Ser Lys Glu Glu Arg Asp Pro Val Lys 
    130                 135                 140                 


Ala His Glu Gly Trp Gly Val Met Leu Pro Cys Asn Pro Pro Ala His 
145                 150                 155                 160 


Tyr Pro Gly Leu Ser Tyr Arg Trp Leu Leu Asn Glu Phe Pro Asn Phe 
                165                 170                 175     


Ile Pro Thr Asp Gly Arg His Phe Val Ser Gln Thr Thr Gly Asn Leu 
            180                 185                 190         


Tyr Ile Ala Arg Thr Asn Ala Ser Asp Leu Gly Asn Tyr Ser Cys Leu 
        195                 200                 205             


Ala Thr Ser His Met Asp Phe Ser Thr Lys Ser Val Phe Ser Lys Phe 
    210                 215                 220                 


Ala Gln Leu Asn Leu Ala Ala Glu Asp Thr Arg Leu Phe Ala Pro Ser 
225                 230                 235                 240 


Ile Lys Ala Arg Phe Pro Ala Glu Thr Tyr Ala Leu Val Gly Gln Gln 
                245                 250                 255     


Val Thr Leu Glu Cys Phe Ala Phe Gly Asn Pro Val Pro Arg Ile Lys 
            260                 265                 270         


Trp Arg Lys Val Asp Gly Ser Leu Ser Pro Gln Trp Thr Thr Ala Glu 
        275                 280                 285             


Pro Thr Leu Gln Ile Pro Ser Val Ser Phe Glu Asp Glu Gly Thr Tyr 
    290                 295                 300                 


Glu Cys Glu Ala Glu Asn Ser Lys Gly Arg Asp Thr Val Gln Gly Arg 
305                 310                 315                 320 


Ile Ile Val Gln Ala Gln Pro Glu Trp Leu Lys Val Ile Ser Asp Thr 
                325                 330                 335     


Glu Ala Asp Ile Gly Ser Asn Leu Arg Trp Gly Cys Ala Ala Ala Gly 
            340                 345                 350         


Lys Pro Arg Pro Thr Val Arg Trp Leu Arg Asn Gly Glu Pro Leu Ala 
        355                 360                 365             


Ser Gln Asn Arg Val Glu Val Leu Ala Gly Asp Leu Arg Phe Ser Lys 
    370                 375                 380                 


Leu Ser Leu Glu Asp Ser Gly Met Tyr Gln Cys Val Ala Glu Asn Lys 
385                 390                 395                 400 


His Gly Thr Ile Tyr Ala Ser Ala Glu Leu Ala Val Gln Ala Leu Ala 
                405                 410                 415     


Pro Asp Phe Arg Leu Asn Pro Val Arg Arg Leu Ile Pro Ala Ala Arg 
            420                 425                 430         


Gly Gly Glu Ile Leu Ile Pro Cys Gln Pro Arg Ala Ala Pro Lys Ala 
        435                 440                 445             


Val Val Leu Trp Ser Lys Gly Thr Glu Ile Leu Val Asn Ser Ser Arg 
    450                 455                 460                 


Val Thr Val Thr Pro Asp Gly Thr Leu Ile Ile Arg Asn Ile Ser Arg 
465                 470                 475                 480 


Ser Asp Glu Gly Lys Tyr Thr Cys Phe Ala Glu Asn Phe Met Gly Lys 
                485                 490                 495     


Ala Asn Ser Thr Gly Ile Leu Ser Val Arg Asp Ala Thr Lys Ile Thr 
            500                 505                 510         


Leu Ala Pro Ser Ser Ala Asp Ile Asn Leu Gly Asp Asn Leu Thr Leu 
        515                 520                 525             


Gln Cys His Ala Ser His Asp Pro Thr Met Asp Leu Thr Phe Thr Trp 
    530                 535                 540                 


Thr Leu Asp Asp Phe Pro Ile Asp Phe Asp Lys Pro Gly Gly His Tyr 
545                 550                 555                 560 


Arg Arg Thr Asn Val Lys Glu Thr Ile Gly Asp Leu Thr Ile Leu Asn 
                565                 570                 575     


Ala Gln Leu Arg His Gly Gly Lys Tyr Thr Cys Met Ala Gln Thr Val 
            580                 585                 590         


Val Asp Ser Ala Ser Lys Glu Ala Thr Val Leu Val Arg Gly Pro Pro 
        595                 600                 605             


Gly Pro Pro Gly Gly Val Val Val Arg Asp Ile Gly Asp Thr Thr Ile 
    610                 615                 620                 


Gln Leu Ser Trp Ser Arg Gly Phe Asp Asn His Ser Pro Ile Ala Lys 
625                 630                 635                 640 


Tyr Thr Leu Gln Ala Arg Thr Pro Pro Ala Gly Lys Trp Lys Gln Val 
                645                 650                 655     


Arg Thr Asn Pro Ala Asn Ile Glu Gly Asn Ala Glu Thr Ala Gln Val 
            660                 665                 670         


Leu Gly Leu Thr Pro Trp Met Asp Tyr Glu Phe Arg Val Ile Ala Ser 
        675                 680                 685             


Asn Ile Leu Gly Thr Gly Glu Pro Ser Gly Pro Ser Ser Lys Ile Arg 
    690                 695                 700                 


Thr Arg Glu Ala Ala Pro Ser Val Ala Pro Ser Gly Leu Ser Gly Gly 
705                 710                 715                 720 


Gly Gly Ala Pro Gly Glu Leu Ile Val Asn Trp Thr Pro Met Ser Arg 
                725                 730                 735     


Glu Tyr Gln Asn Gly Asp Gly Phe Gly Tyr Leu Leu Ser Phe Arg Arg 
            740                 745                 750         


Gln Gly Ser Thr His Trp Gln Thr Ala Arg Val Pro Gly Ala Asp Ala 
        755                 760                 765             


Gln Tyr Phe Val Tyr Ser Asn Glu Ser Val Arg Pro Tyr Thr Pro Phe 
    770                 775                 780                 


Glu Val Lys Ile Arg Ser Tyr Asn Arg Arg Gly Asp Gly Pro Glu Ser 
785                 790                 795                 800 


Leu Thr Ala Leu Val Tyr Ser Ala Glu Glu Glu Pro Arg Val Ala Pro 
                805                 810                 815     


Thr Lys Val Trp Ala Lys Gly Val Ser Ser Ser Glu Met Asn Val Thr 
            820                 825                 830         


Trp Glu Pro Val Gln Gln Asp Met Asn Gly Ile Leu Leu Gly Tyr Glu 
        835                 840                 845             


Ile Arg Tyr Trp Lys Ala Gly Asp Lys Glu Ala Ala Ala Asp Arg Val 
    850                 855                 860                 


Arg Thr Ala Gly Leu Asp Thr Ser Ala Arg Val Ser Gly Leu His Pro 
865                 870                 875                 880 


Asn Thr Lys Tyr His Val Thr Val Arg Ala Tyr Asn Arg Ala Gly Thr 
                885                 890                 895     


Gly Pro Ala Ser Pro Ser Ala Asn Ala Thr Thr Met Lys Pro Pro Pro 
            900                 905                 910         


Arg Arg Pro Pro Gly Asn Ile Ser Trp Thr Phe Ser Ser Ser Ser Leu 
        915                 920                 925             


Ser Ile Lys Trp Asp Pro Val Val Pro Phe Arg Asn Glu Ser Ala Val 
    930                 935                 940                 


Thr Gly Tyr Lys Met Leu Tyr Gln Asn Asp Leu His Leu Thr Pro Thr 
945                 950                 955                 960 


Leu His Leu Thr Gly Lys Asn Trp Ile Glu Ile Pro Val Pro Glu Asp 
                965                 970                 975     


Ile Gly His Ala Leu Val Gln Ile Arg Thr Thr Gly Pro Gly Gly Asp 
            980                 985                 990         


Gly Ile Pro Ala Glu Val His Ile  Val Arg Asn Gly Gly  Thr Ser Met 
        995                 1000                 1005             


Met Val  Glu Asn Met Ala Val  Arg Pro Ala Pro His  Pro Gly Thr 
    1010                 1015                 1020             


Val Ile  Ser His Ser Val Ala  Met Leu Ile Leu Ile  Gly Ser Leu 
    1025                 1030                 1035             


Glu Leu  
    1040 


<210>  3949
<211>  1152
<212>  PRT
<213>  homo sapiens

<400>  3949

Met Ala Val Arg Lys Lys Asp Gly Gly Pro Asn Val Lys Tyr Tyr Glu 
1               5                   10                  15      


Ala Ala Asp Thr Val Thr Gln Phe Asp Asn Val Arg Leu Trp Leu Gly 
            20                  25                  30          


Lys Asn Tyr Lys Lys Tyr Ile Gln Ala Glu Pro Pro Thr Asn Lys Ser 
        35                  40                  45              


Leu Ser Ser Leu Val Val Gln Leu Leu Gln Phe Gln Glu Glu Val Phe 
    50                  55                  60                  


Gly Lys His Val Ser Asn Ala Pro Leu Thr Lys Leu Pro Ile Lys Cys 
65                  70                  75                  80  


Phe Leu Asp Phe Lys Ala Gly Gly Ser Leu Cys His Ile Leu Ala Ala 
                85                  90                  95      


Ala Tyr Lys Phe Lys Ser Asp Gln Gly Trp Arg Arg Tyr Asp Phe Gln 
            100                 105                 110         


Asn Pro Ser Arg Met Asp Arg Asn Val Glu Met Phe Met Thr Ile Glu 
        115                 120                 125             


Lys Ser Leu Val Gln Asn Asn Cys Leu Ser Arg Pro Asn Ile Phe Leu 
    130                 135                 140                 


Cys Pro Glu Ile Glu Pro Lys Leu Leu Gly Lys Leu Lys Asp Ile Ile 
145                 150                 155                 160 


Lys Arg His Gln Gly Thr Val Thr Glu Asp Lys Asn Asn Ala Ser His 
                165                 170                 175     


Val Val Tyr Pro Val Pro Gly Asn Leu Glu Glu Glu Glu Trp Val Arg 
            180                 185                 190         


Pro Val Met Lys Arg Asp Lys Gln Val Leu Leu His Trp Gly Tyr Tyr 
        195                 200                 205             


Pro Asp Ser Tyr Asp Thr Trp Ile Pro Ala Ser Glu Ile Glu Ala Ser 
    210                 215                 220                 


Val Glu Asp Ala Pro Thr Pro Glu Lys Pro Arg Lys Val His Ala Lys 
225                 230                 235                 240 


Trp Ile Leu Asp Thr Asp Thr Phe Asn Glu Trp Met Asn Glu Glu Asp 
                245                 250                 255     


Tyr Glu Val Asn Asp Asp Lys Asn Pro Val Ser Arg Arg Lys Lys Ile 
            260                 265                 270         


Ser Ala Lys Thr Leu Thr Asp Glu Val Asn Ser Pro Asp Ser Asp Arg 
        275                 280                 285             


Arg Asp Lys Lys Gly Gly Asn Tyr Lys Lys Arg Lys Arg Ser Pro Ser 
    290                 295                 300                 


Pro Ser Pro Thr Pro Glu Ala Lys Lys Lys Asn Ala Lys Lys Gly Pro 
305                 310                 315                 320 


Ser Thr Pro Tyr Thr Lys Ser Lys Arg Gly His Arg Glu Glu Glu Gln 
                325                 330                 335     


Glu Asp Leu Thr Lys Asp Met Asp Glu Pro Ser Pro Val Pro Asn Val 
            340                 345                 350         


Glu Glu Val Thr Leu Pro Lys Thr Val Asn Thr Lys Lys Asp Ser Glu 
        355                 360                 365             


Ser Ala Pro Val Lys Gly Gly Thr Met Thr Asp Leu Asp Glu Gln Glu 
    370                 375                 380                 


Asp Glu Ser Met Glu Thr Thr Gly Lys Asp Glu Asp Glu Asn Ser Thr 
385                 390                 395                 400 


Gly Asn Lys Gly Glu Gln Thr Lys Asn Pro Asp Leu His Glu Asp Asn 
                405                 410                 415     


Val Thr Glu Gln Thr His His Ile Ile Ile Pro Ser Tyr Ala Ala Trp 
            420                 425                 430         


Phe Asp Tyr Asn Ser Val His Ala Ile Glu Arg Arg Ala Leu Pro Glu 
        435                 440                 445             


Phe Phe Asn Gly Lys Asn Lys Ser Lys Thr Pro Glu Ile Tyr Leu Ala 
    450                 455                 460                 


Tyr Arg Asn Phe Met Ile Asp Thr Tyr Arg Leu Asn Pro Gln Glu Tyr 
465                 470                 475                 480 


Leu Thr Ser Thr Ala Cys Arg Arg Asn Leu Ala Gly Asp Val Cys Ala 
                485                 490                 495     


Ile Met Arg Val His Ala Phe Leu Glu Gln Trp Gly Leu Ile Asn Tyr 
            500                 505                 510         


Gln Val Asp Ala Glu Ser Arg Pro Thr Pro Met Gly Pro Pro Pro Thr 
        515                 520                 525             


Ser His Phe His Val Leu Ala Asp Thr Pro Ser Gly Leu Val Pro Leu 
    530                 535                 540                 


Gln Pro Lys Thr Pro Gln Gly Arg Gln Val Asp Ala Asp Thr Lys Ala 
545                 550                 555                 560 


Gly Arg Lys Gly Lys Glu Leu Asp Asp Leu Val Pro Glu Thr Ala Lys 
                565                 570                 575     


Gly Lys Pro Glu Leu Gln Thr Ser Ala Ser Gln Gln Met Leu Asn Phe 
            580                 585                 590         


Pro Asp Lys Gly Lys Glu Lys Pro Thr Asp Met Gln Asn Phe Gly Leu 
        595                 600                 605             


Arg Thr Asp Met Tyr Thr Lys Lys Asn Val Pro Ser Lys Ser Lys Ala 
    610                 615                 620                 


Ala Ala Ser Ala Thr Arg Glu Trp Thr Glu Gln Glu Thr Leu Leu Leu 
625                 630                 635                 640 


Leu Glu Ala Leu Glu Met Tyr Lys Asp Asp Trp Asn Lys Val Ser Glu 
                645                 650                 655     


His Val Gly Ser Arg Thr Gln Asp Glu Cys Ile Leu His Phe Leu Arg 
            660                 665                 670         


Leu Pro Ile Glu Asp Pro Tyr Leu Glu Asp Ser Glu Ala Ser Leu Gly 
        675                 680                 685             


Pro Leu Ala Tyr Gln Pro Ile Pro Phe Ser Gln Ser Gly Asn Pro Val 
    690                 695                 700                 


Met Ser Thr Val Ala Phe Leu Ala Ser Val Val Asp Pro Arg Val Ala 
705                 710                 715                 720 


Ser Ala Ala Ala Lys Ser Ala Leu Glu Glu Phe Ser Lys Met Lys Glu 
                725                 730                 735     


Glu Val Pro Thr Ala Leu Val Glu Ala His Val Arg Lys Val Glu Glu 
            740                 745                 750         


Ala Ala Lys Val Thr Gly Lys Ala Asp Pro Ala Phe Gly Leu Glu Ser 
        755                 760                 765             


Ser Gly Ile Ala Gly Thr Thr Ser Asp Glu Pro Glu Arg Ile Glu Glu 
    770                 775                 780                 


Ser Gly Asn Asp Glu Ala Arg Val Glu Gly Gln Ala Thr Asp Glu Lys 
785                 790                 795                 800 


Lys Glu Pro Lys Glu Pro Arg Glu Gly Gly Gly Ala Ile Glu Glu Glu 
                805                 810                 815     


Ala Lys Glu Lys Thr Ser Glu Ala Pro Lys Lys Asp Glu Glu Lys Gly 
            820                 825                 830         


Lys Glu Gly Asp Ser Glu Lys Glu Ser Glu Lys Ser Asp Gly Asp Pro 
        835                 840                 845             


Ile Val Asp Pro Glu Lys Glu Lys Glu Pro Lys Glu Gly Gln Glu Glu 
    850                 855                 860                 


Val Leu Lys Glu Val Val Glu Ser Glu Gly Glu Arg Lys Thr Lys Val 
865                 870                 875                 880 


Glu Arg Asp Ile Gly Glu Gly Asn Leu Ser Thr Ala Ala Ala Ala Ala 
                885                 890                 895     


Leu Ala Ala Ala Ala Val Lys Ala Lys His Leu Ala Ala Val Glu Glu 
            900                 905                 910         


Arg Lys Ile Lys Ser Leu Val Ala Leu Leu Val Glu Thr Gln Met Lys 
        915                 920                 925             


Lys Leu Glu Ile Lys Leu Arg His Phe Glu Glu Leu Glu Thr Ile Met 
    930                 935                 940                 


Asp Arg Glu Arg Glu Ala Leu Glu Tyr Gln Arg Gln Gln Leu Leu Ala 
945                 950                 955                 960 


Asp Arg Gln Ala Phe His Met Glu Gln Leu Lys Tyr Ala Glu Met Arg 
                965                 970                 975     


Ala Arg Gln Gln His Phe Gln Gln Met His Gln Gln Gln Gln Gln Pro 
            980                 985                 990         


Pro Pro Ala Leu Pro Pro Gly Ser  Gln Pro Ile Pro Pro  Thr Gly Ala 
        995                 1000                 1005             


Ala Gly  Pro Pro Ala Val His  Gly Leu Ala Val Ala  Pro Ala Ser 
    1010                 1015                 1020             


Val Val  Pro Ala Pro Ala Gly  Ser Gly Ala Pro Pro  Gly Ser Leu 
    1025                 1030                 1035             


Gly Pro  Ser Glu Gln Ile Gly  Gln Ala Gly Ser Thr  Ala Gly Pro 
    1040                 1045                 1050             


Gln Gln  Gln Gln Pro Ala Gly  Ala Pro Gln Pro Gly  Ala Val Pro 
    1055                 1060                 1065             


Pro Gly  Val Pro Pro Pro Gly  Pro His Gly Pro Ser  Pro Phe Pro 
    1070                 1075                 1080             


Asn Gln  Gln Thr Pro Pro Ser  Met Met Pro Gly Ala  Val Pro Gly 
    1085                 1090                 1095             


Ser Gly  His Pro Gly Val Ala  Ala Gln Ser Pro Ala  Ile Val Ala 
    1100                 1105                 1110             


Ala Val  Gln Gly Asn Leu Leu  Pro Ser Ala Ser Pro  Leu Pro Asp 
    1115                 1120                 1125             


Pro Gly  Thr Pro Leu Pro Pro  Asp Pro Thr Ala Pro  Ser Pro Gly 
    1130                 1135                 1140             


Thr Val  Thr Pro Val Pro Pro  Pro Gln 
    1145                 1150         


<210>  3950
<211>  496
<212>  PRT
<213>  homo sapiens

<400>  3950

Met Gly Arg Arg Ala Leu Leu Leu Leu Leu Leu Ser Phe Leu Ala Pro 
1               5                   10                  15      


Trp Ala Thr Ile Ala Leu Arg Pro Ala Leu Arg Ala Leu Gly Ser Leu 
            20                  25                  30          


His Leu Pro Thr Asn Pro Thr Ser Leu Pro Ala Val Ala Lys Asn Tyr 
        35                  40                  45              


Ser Val Leu Tyr Phe Gln Gln Lys Val Asp His Phe Gly Phe Asn Thr 
    50                  55                  60                  


Val Lys Thr Phe Asn Gln Arg Tyr Leu Val Ala Asp Lys Tyr Trp Lys 
65                  70                  75                  80  


Lys Asn Gly Gly Ser Ile Leu Phe Tyr Thr Gly Asn Glu Gly Asp Ile 
                85                  90                  95      


Ile Trp Phe Cys Asn Asn Thr Gly Phe Met Trp Asp Val Ala Glu Glu 
            100                 105                 110         


Leu Lys Ala Met Leu Val Phe Ala Glu His Arg Tyr Tyr Gly Glu Ser 
        115                 120                 125             


Leu Pro Phe Gly Asp Asn Ser Phe Lys Asp Ser Arg His Leu Asn Phe 
    130                 135                 140                 


Leu Thr Ser Glu Gln Ala Leu Ala Asp Phe Ala Glu Leu Ile Lys His 
145                 150                 155                 160 


Leu Lys Arg Thr Ile Pro Gly Ala Glu Asn Gln Pro Val Ile Ala Ile 
                165                 170                 175     


Gly Gly Ser Tyr Gly Gly Met Leu Ala Ala Trp Phe Arg Met Lys Tyr 
            180                 185                 190         


Pro His Met Val Val Gly Ala Leu Ala Ala Ser Ala Pro Ile Trp Gln 
        195                 200                 205             


Phe Glu Asp Leu Val Pro Cys Gly Val Phe Met Lys Ile Val Thr Thr 
    210                 215                 220                 


Asp Phe Arg Lys Ser Gly Pro His Cys Ser Glu Ser Ile His Arg Ser 
225                 230                 235                 240 


Trp Asp Ala Ile Asn Arg Leu Ser Asn Thr Gly Ser Gly Leu Gln Trp 
                245                 250                 255     


Leu Thr Gly Ala Leu His Leu Cys Ser Pro Leu Thr Ser Gln Asp Ile 
            260                 265                 270         


Gln His Leu Lys Asp Trp Ile Ser Glu Thr Trp Val Asn Leu Ala Met 
        275                 280                 285             


Val Asp Tyr Pro Tyr Ala Ser Asn Phe Leu Gln Pro Leu Pro Ala Trp 
    290                 295                 300                 


Pro Ile Lys Val Val Cys Gln Tyr Leu Lys Asn Pro Asn Val Ser Asp 
305                 310                 315                 320 


Ser Leu Leu Leu Gln Asn Ile Phe Gln Ala Leu Asn Val Tyr Tyr Asn 
                325                 330                 335     


Tyr Ser Gly Gln Val Lys Cys Leu Asn Ile Ser Glu Thr Ala Thr Ser 
            340                 345                 350         


Ser Leu Gly Thr Leu Gly Trp Ser Tyr Gln Ala Cys Thr Glu Val Val 
        355                 360                 365             


Met Pro Phe Cys Thr Asn Gly Val Asp Asp Met Phe Glu Pro His Ser 
    370                 375                 380                 


Trp Asn Leu Lys Glu Leu Ser Asp Asp Cys Phe Gln Gln Trp Gly Val 
385                 390                 395                 400 


Arg Pro Arg Pro Ser Trp Ile Thr Thr Met Tyr Gly Gly Lys Asn Ile 
                405                 410                 415     


Ser Ser His Thr Asn Ile Val Phe Ser Asn Gly Glu Leu Asp Pro Trp 
            420                 425                 430         


Ser Gly Gly Gly Val Thr Lys Asp Ile Thr Asp Thr Leu Val Ala Val 
        435                 440                 445             


Thr Ile Ser Glu Gly Ala His His Leu Asp Leu Arg Thr Lys Asn Ala 
    450                 455                 460                 


Leu Asp Pro Met Ser Val Leu Leu Ala Arg Ser Leu Glu Val Arg His 
465                 470                 475                 480 


Met Lys Asn Trp Ile Arg Asp Phe Tyr Asp Ser Ala Gly Lys Gln His 
                485                 490                 495     


<210>  3951
<211>  552
<212>  PRT
<213>  homo sapiens

<400>  3951

Met Asp Asn Met Ser Ile Thr Asn Thr Pro Thr Ser Asn Asp Ala Cys 
1               5                   10                  15      


Leu Ser Ile Val His Ser Leu Met Cys His Arg Gln Gly Gly Glu Ser 
            20                  25                  30          


Glu Thr Phe Ala Lys Arg Ala Ile Glu Ser Leu Val Lys Lys Leu Lys 
        35                  40                  45              


Glu Lys Lys Asp Glu Leu Asp Ser Leu Ile Thr Ala Ile Thr Thr Asn 
    50                  55                  60                  


Gly Ala His Pro Ser Lys Cys Val Thr Ile Gln Arg Thr Leu Asp Gly 
65                  70                  75                  80  


Arg Leu Gln Val Ala Gly Arg Lys Gly Phe Pro His Val Ile Tyr Ala 
                85                  90                  95      


Arg Leu Trp Arg Trp Pro Asp Leu His Lys Asn Glu Leu Lys His Val 
            100                 105                 110         


Lys Tyr Cys Gln Tyr Ala Phe Asp Leu Lys Cys Asp Ser Val Cys Val 
        115                 120                 125             


Asn Pro Tyr His Tyr Glu Arg Val Val Ser Pro Gly Ile Asp Leu Ser 
    130                 135                 140                 


Gly Leu Thr Leu Gln Ser Asn Ala Pro Ser Ser Met Met Val Lys Asp 
145                 150                 155                 160 


Glu Tyr Val His Asp Phe Glu Gly Gln Pro Ser Leu Ser Thr Glu Gly 
                165                 170                 175     


His Ser Ile Gln Thr Ile Gln His Pro Pro Ser Asn Arg Ala Ser Thr 
            180                 185                 190         


Glu Thr Tyr Ser Thr Pro Ala Leu Leu Ala Pro Ser Glu Ser Asn Ala 
        195                 200                 205             


Thr Ser Thr Ala Asn Phe Pro Asn Ile Pro Val Ala Ser Thr Ser Gln 
    210                 215                 220                 


Pro Ala Ser Ile Leu Gly Gly Ser His Ser Glu Gly Leu Leu Gln Ile 
225                 230                 235                 240 


Ala Ser Gly Pro Gln Pro Gly Gln Gln Gln Asn Gly Phe Thr Gly Gln 
                245                 250                 255     


Pro Ala Thr Tyr His His Asn Ser Thr Thr Thr Trp Thr Gly Ser Arg 
            260                 265                 270         


Thr Ala Pro Tyr Thr Pro Asn Leu Pro His His Gln Asn Gly His Leu 
        275                 280                 285             


Gln His His Pro Pro Met Pro Pro His Pro Gly His Tyr Trp Pro Val 
    290                 295                 300                 


His Asn Glu Leu Ala Phe Gln Pro Pro Ile Ser Asn His Pro Ala Pro 
305                 310                 315                 320 


Glu Tyr Trp Cys Ser Ile Ala Tyr Phe Glu Met Asp Val Gln Val Gly 
                325                 330                 335     


Glu Thr Phe Lys Val Pro Ser Ser Cys Pro Ile Val Thr Val Asp Gly 
            340                 345                 350         


Tyr Val Asp Pro Ser Gly Gly Asp Arg Phe Cys Leu Gly Gln Leu Ser 
        355                 360                 365             


Asn Val His Arg Thr Glu Ala Ile Glu Arg Ala Arg Leu His Ile Gly 
    370                 375                 380                 


Lys Gly Val Gln Leu Glu Cys Lys Gly Glu Gly Asp Val Trp Val Arg 
385                 390                 395                 400 


Cys Leu Ser Asp His Ala Val Phe Val Gln Ser Tyr Tyr Leu Asp Arg 
                405                 410                 415     


Glu Ala Gly Arg Ala Pro Gly Asp Ala Val His Lys Ile Tyr Pro Ser 
            420                 425                 430         


Ala Tyr Ile Lys Val Phe Asp Leu Arg Gln Cys His Arg Gln Met Gln 
        435                 440                 445             


Gln Gln Ala Ala Thr Ala Gln Ala Ala Ala Ala Ala Gln Ala Ala Ala 
    450                 455                 460                 


Val Ala Gly Asn Ile Pro Gly Pro Gly Ser Val Gly Gly Ile Ala Pro 
465                 470                 475                 480 


Ala Ile Ser Leu Ser Ala Ala Ala Gly Ile Gly Val Asp Asp Leu Arg 
                485                 490                 495     


Arg Leu Cys Ile Leu Arg Met Ser Phe Val Lys Gly Trp Gly Pro Asp 
            500                 505                 510         


Tyr Pro Arg Gln Ser Ile Lys Glu Thr Pro Cys Trp Ile Glu Ile His 
        515                 520                 525             


Leu His Arg Ala Leu Gln Leu Leu Asp Glu Val Leu His Thr Met Pro 
    530                 535                 540                 


Ile Ala Asp Pro Gln Pro Leu Asp 
545                 550         


<210>  3952
<211>  299
<212>  PRT
<213>  homo sapiens

<400>  3952

Met Asp Leu Ser Glu Leu Glu Arg Asp Asn Thr Gly Arg Cys Arg Leu 
1               5                   10                  15      


Ser Ser Pro Val Pro Ala Val Cys Arg Lys Glu Pro Cys Val Leu Gly 
            20                  25                  30          


Val Asp Glu Ala Gly Arg Gly Pro Val Leu Gly Pro Met Val Tyr Ala 
        35                  40                  45              


Ile Cys Tyr Cys Pro Leu Pro Arg Leu Ala Asp Leu Glu Ala Leu Lys 
    50                  55                  60                  


Val Ala Asp Ser Lys Thr Leu Leu Glu Ser Glu Arg Glu Arg Leu Phe 
65                  70                  75                  80  


Ala Lys Met Glu Asp Thr Asp Phe Val Gly Trp Ala Leu Asp Val Leu 
                85                  90                  95      


Ser Pro Asn Leu Ile Ser Thr Ser Met Leu Gly Arg Val Lys Tyr Asn 
            100                 105                 110         


Leu Asn Ser Leu Ser His Asp Thr Ala Thr Gly Leu Ile Gln Tyr Ala 
        115                 120                 125             


Leu Asp Gln Gly Val Asn Val Thr Gln Val Phe Val Asp Thr Val Gly 
    130                 135                 140                 


Met Pro Glu Thr Tyr Gln Ala Arg Leu Gln Gln Ser Phe Pro Gly Ile 
145                 150                 155                 160 


Glu Val Thr Val Lys Ala Lys Ala Asp Ala Leu Tyr Pro Val Val Ser 
                165                 170                 175     


Ala Ala Ser Ile Cys Ala Lys Val Ala Arg Asp Gln Ala Val Lys Lys 
            180                 185                 190         


Trp Gln Phe Val Glu Lys Leu Gln Asp Leu Asp Thr Asp Tyr Gly Ser 
        195                 200                 205             


Gly Tyr Pro Asn Asp Pro Lys Thr Lys Ala Trp Leu Lys Glu His Val 
    210                 215                 220                 


Glu Pro Val Phe Gly Phe Pro Gln Phe Val Arg Phe Ser Trp Arg Thr 
225                 230                 235                 240 


Ala Gln Thr Ile Leu Glu Lys Glu Ala Glu Asp Val Ile Trp Glu Asp 
                245                 250                 255     


Ser Ala Ser Glu Asn Gln Glu Gly Leu Arg Lys Ile Thr Ser Tyr Phe 
            260                 265                 270         


Leu Asn Glu Gly Ser Gln Ala Arg Pro Arg Ser Ser His Arg Tyr Phe 
        275                 280                 285             


Leu Glu Arg Gly Leu Glu Ser Ala Thr Ser Leu 
    290                 295                 


<210>  3953
<211>  168
<212>  PRT
<213>  homo sapiens

<400>  3953

Met Asn Ser Lys Gly Gln Tyr Pro Thr Gln Pro Thr Tyr Pro Val Gln 
1               5                   10                  15      


Pro Pro Gly Asn Pro Val Tyr Pro Gln Thr Leu His Leu Pro Gln Ala 
            20                  25                  30          


Pro Pro Tyr Thr Asp Ala Pro Pro Ala Tyr Ser Glu Leu Tyr Arg Pro 
        35                  40                  45              


Ser Phe Val His Pro Gly Ala Ala Thr Val Pro Thr Met Ser Ala Ala 
    50                  55                  60                  


Phe Pro Gly Ala Ser Leu Tyr Leu Pro Met Ala Gln Ser Val Ala Val 
65                  70                  75                  80  


Gly Pro Leu Gly Ser Thr Ile Pro Met Ala Tyr Tyr Pro Val Gly Pro 
                85                  90                  95      


Ile Tyr Pro Pro Gly Ser Thr Val Leu Val Glu Gly Gly Tyr Asp Ala 
            100                 105                 110         


Gly Ala Arg Phe Gly Ala Gly Ala Thr Ala Gly Asn Ile Pro Pro Pro 
        115                 120                 125             


Pro Pro Gly Cys Pro Pro Asn Ala Ala Gln Leu Ala Val Met Gln Gly 
    130                 135                 140                 


Ala Asn Val Leu Val Thr Gln Arg Lys Gly Asn Phe Phe Met Gly Gly 
145                 150                 155                 160 


Ser Asp Gly Gly Tyr Thr Ile Trp 
                165             


<210>  3954
<211>  2948
<212>  PRT
<213>  homo sapiens

<400>  3954

Met Gly Asn Glu Asn Ser Thr Ser Asp Asn Gln Arg Thr Leu Ser Ala 
1               5                   10                  15      


Gln Thr Pro Arg Ser Ala Gln Pro Pro Gly Asn Ser Gln Asn Ile Lys 
            20                  25                  30          


Arg Lys Gln Gln Asp Thr Pro Gly Ser Pro Asp His Arg Asp Ala Ser 
        35                  40                  45              


Ser Ile Gly Ser Val Gly Leu Gly Gly Phe Cys Thr Ala Ser Glu Ser 
    50                  55                  60                  


Ser Ala Ser Leu Asp Pro Cys Leu Val Ser Pro Glu Val Thr Glu Pro 
65                  70                  75                  80  


Arg Lys Asp Pro Gln Gly Ala Arg Gly Pro Glu Gly Ser Leu Leu Pro 
                85                  90                  95      


Ser Pro Pro Pro Ser Gln Glu Arg Glu His Pro Ser Ser Ser Met Pro 
            100                 105                 110         


Phe Ala Glu Cys Pro Pro Glu Gly Cys Leu Ala Ser Pro Ala Ala Ala 
        115                 120                 125             


Pro Glu Asp Gly Pro Gln Thr Gln Ser Pro Arg Arg Glu Pro Ala Pro 
    130                 135                 140                 


Asn Ala Pro Gly Asp Ile Ala Ala Ala Phe Pro Ala Glu Arg Asp Ser 
145                 150                 155                 160 


Ser Thr Pro Tyr Gln Glu Ile Ala Ala Val Pro Ser Ala Gly Arg Glu 
                165                 170                 175     


Arg Gln Pro Lys Glu Glu Gly Gln Lys Ser Ser Phe Ser Phe Ser Ser 
            180                 185                 190         


Gly Ile Asp Gln Ser Pro Gly Met Ser Pro Val Pro Leu Arg Glu Pro 
        195                 200                 205             


Met Lys Ala Pro Leu Cys Gly Glu Gly Asp Gln Pro Gly Gly Phe Glu 
    210                 215                 220                 


Ser Gln Glu Lys Glu Ala Ala Gly Gly Phe Pro Pro Ala Glu Ser Arg 
225                 230                 235                 240 


Gln Gly Val Ala Ser Val Gln Val Thr Pro Glu Ala Pro Ala Ala Ala 
                245                 250                 255     


Gln Gln Gly Thr Glu Ser Ser Ala Val Leu Glu Lys Ser Pro Leu Lys 
            260                 265                 270         


Pro Met Ala Pro Ile Pro Gln Asp Pro Ala Pro Arg Ala Ser Asp Arg 
        275                 280                 285             


Glu Arg Gly Gln Gly Glu Ala Pro Pro Gln Tyr Leu Thr Asp Asp Leu 
    290                 295                 300                 


Glu Phe Leu Arg Ala Cys His Leu Pro Arg Ser Asn Ser Gly Ala Ala 
305                 310                 315                 320 


Pro Glu Ala Glu Val Asn Ala Ala Ser Gln Glu Ser Cys Gln Gln Pro 
                325                 330                 335     


Val Gly Ala Tyr Leu Pro His Ala Glu Leu Pro Trp Gly Leu Pro Ser 
            340                 345                 350         


Pro Ala Leu Val Pro Glu Ala Gly Gly Ser Gly Lys Glu Ala Leu Asp 
        355                 360                 365             


Thr Ile Asp Val Gln Gly His Pro Gln Thr Gly Met Arg Gly Thr Lys 
    370                 375                 380                 


Pro Asn Gln Val Val Cys Val Ala Ala Gly Gly Gln Pro Glu Gly Gly 
385                 390                 395                 400 


Leu Pro Val Ser Pro Glu Pro Ser Leu Leu Thr Pro Thr Glu Glu Ala 
                405                 410                 415     


His Pro Ala Ser Ser Leu Ala Ser Phe Pro Ala Ala Gln Ile Pro Ile 
            420                 425                 430         


Ala Val Glu Glu Pro Gly Ser Ser Ser Arg Glu Ser Val Ser Lys Ala 
        435                 440                 445             


Gly Met Pro Val Ser Ala Asp Ala Ala Lys Glu Val Val Asp Ala Gly 
    450                 455                 460                 


Leu Val Gly Leu Glu Arg Gln Val Ser Asp Leu Gly Ser Lys Gly Glu 
465                 470                 475                 480 


His Pro Glu Gly Asp Pro Gly Glu Val Pro Ala Pro Ser Pro Gln Glu 
                485                 490                 495     


Arg Gly Glu His Leu Asn Thr Glu Gln Ser His Glu Val Gln Pro Gly 
            500                 505                 510         


Val Pro Pro Pro Pro Leu Pro Lys Glu Gln Ser His Glu Val Gln Pro 
        515                 520                 525             


Gly Ala Pro Pro Pro Pro Leu Pro Lys Ala Pro Ser Glu Ser Ala Arg 
    530                 535                 540                 


Gly Pro Pro Gly Pro Thr Asp Gly Ala Lys Val His Glu Asp Ser Thr 
545                 550                 555                 560 


Ser Pro Ala Val Ala Lys Glu Gly Ser Arg Ser Pro Gly Asp Ser Pro 
                565                 570                 575     


Gly Gly Lys Glu Glu Ala Pro Glu Pro Pro Asp Gly Gly Asp Pro Gly 
            580                 585                 590         


Asn Leu Gln Gly Glu Asp Ser Gln Ala Phe Ser Ser Lys Arg Asp Pro 
        595                 600                 605             


Glu Val Gly Lys Asp Glu Leu Ser Lys Pro Ser Ser Asp Ala Glu Ser 
    610                 615                 620                 


Arg Asp His Pro Ser Ser His Ser Ala Gln Pro Pro Arg Lys Gly Gly 
625                 630                 635                 640 


Ala Gly His Thr Asp Gly Pro His Ser Gln Thr Ala Glu Ala Asp Ala 
                645                 650                 655     


Ser Gly Leu Pro His Lys Leu Gly Glu Glu Asp Pro Val Leu Pro Pro 
            660                 665                 670         


Val Pro Asp Gly Ala Gly Glu Pro Thr Val Pro Glu Gly Ala Ile Trp 
        675                 680                 685             


Glu Gly Ser Gly Leu Gln Pro Lys Cys Pro Asp Thr Leu Gln Ser Arg 
    690                 695                 700                 


Glu Gly Leu Gly Arg Met Glu Ser Phe Leu Thr Leu Glu Ser Glu Lys 
705                 710                 715                 720 


Ser Asp Phe Pro Pro Thr Pro Val Ala Glu Val Ala Pro Lys Ala Gln 
                725                 730                 735     


Glu Gly Glu Ser Thr Leu Glu Ile Arg Lys Met Gly Ser Cys Asp Gly 
            740                 745                 750         


Glu Gly Leu Leu Thr Ser Pro Asp Gln Pro Arg Gly Pro Ala Cys Asp 
        755                 760                 765             


Ala Ser Arg Gln Glu Phe His Ala Gly Val Pro His Pro Pro Gln Gly 
    770                 775                 780                 


Glu Asn Leu Ala Ala Asp Leu Gly Leu Thr Ala Leu Ile Leu Asp Gln 
785                 790                 795                 800 


Asp Gln Gln Gly Ile Pro Ser Cys Pro Gly Glu Gly Trp Ile Arg Gly 
                805                 810                 815     


Ala Ala Ser Glu Trp Pro Leu Leu Ser Ser Glu Lys His Leu Gln Pro 
            820                 825                 830         


Ser Gln Ala Gln Pro Glu Thr Ser Ile Phe Asp Val Leu Lys Glu Gln 
        835                 840                 845             


Ala Gln Pro Pro Glu Asn Gly Lys Glu Thr Ser Pro Ser His Pro Gly 
    850                 855                 860                 


Phe Lys Asp Gln Gly Ala Asp Ser Ser Gln Ile His Val Pro Val Glu 
865                 870                 875                 880 


Pro Gln Glu Asp Asn Asn Leu Pro Thr His Gly Gly Gln Glu Gln Ala 
                885                 890                 895     


Leu Gly Ser Glu Leu Gln Ser Gln Leu Pro Lys Gly Thr Leu Ser Asp 
            900                 905                 910         


Thr Pro Thr Ser Ser Pro Thr Asp Met Val Trp Glu Ser Ser Leu Thr 
        915                 920                 925             


Glu Glu Ser Glu Leu Ser Ala Pro Thr Arg Gln Lys Leu Pro Ala Leu 
    930                 935                 940                 


Gly Glu Lys Arg Pro Glu Gly Ala Cys Gly Asp Gly Gln Ser Ser Arg 
945                 950                 955                 960 


Val Ser Pro Pro Ala Ala Asp Val Leu Lys Asp Phe Ser Leu Ala Gly 
                965                 970                 975     


Asn Phe Ser Arg Lys Glu Thr Cys Cys Thr Gly Gln Gly Pro Asn Lys 
            980                 985                 990         


Ser Gln Gln Ala Leu Ala Asp Ala  Leu Glu Glu Gly Ser  Gln His Glu 
        995                 1000                 1005             


Glu Ala  Cys Gln Arg His Pro  Gly Ala Ser Glu Ala  Ala Asp Gly 
    1010                 1015                 1020             


Cys Ser  Pro Leu Trp Gly Leu  Ser Lys Arg Glu Met  Ala Ser Gly 
    1025                 1030                 1035             


Asn Thr  Gly Glu Ala Pro Pro  Cys Gln Pro Asp Ser  Val Ala Leu 
    1040                 1045                 1050             


Leu Asp  Ala Val Pro Cys Leu  Pro Ala Leu Ala Pro  Ala Ser Pro 
    1055                 1060                 1065             


Gly Val  Thr Pro Thr Gln Asp  Ala Pro Glu Thr Glu  Ala Cys Asp 
    1070                 1075                 1080             


Glu Thr  Gln Glu Gly Arg Gln  Gln Pro Val Pro Ala  Pro Gln Gln 
    1085                 1090                 1095             


Lys Met  Glu Cys Arg Ala Thr  Ser Asp Ala Glu Ser  Pro Lys Leu 
    1100                 1105                 1110             


Leu Ala  Ser Phe Pro Ser Ala  Gly Glu Gln Gly Gly  Glu Ala Gly 
    1115                 1120                 1125             


Ala Ala  Glu Thr Gly Gly Ser  Ala Gly Ala Gly Asp  Pro Gly Lys 
    1130                 1135                 1140             


Gln Gln  Ala Pro Glu Lys Pro  Gly Glu Ala Thr Leu  Ser Cys Gly 
    1145                 1150                 1155             


Leu Leu  Gln Thr Glu His Cys  Leu Thr Ser Gly Glu  Glu Ala Ser 
    1160                 1165                 1170             


Thr Ser  Ala Leu Arg Glu Ser  Cys Gln Ala Glu His  Pro Met Ala 
    1175                 1180                 1185             


Ser Cys  Gln Asp Ala Leu Leu  Pro Ala Arg Glu Leu  Gly Gly Ile 
    1190                 1195                 1200             


Pro Arg  Ser Thr Met Asp Phe  Ser Thr His Gln Ala  Val Pro Asp 
    1205                 1210                 1215             


Pro Lys  Glu Leu Leu Leu Ser  Gly Pro Pro Glu Val  Ala Ala Pro 
    1220                 1225                 1230             


Asp Thr  Pro Tyr Leu His Val  Asp Ser Ala Ala Gln  Arg Gly Ala 
    1235                 1240                 1245             


Glu Asp  Ser Gly Val Lys Ala  Val Ser Ser Ala Asp  Pro Arg Ala 
    1250                 1255                 1260             


Pro Gly  Glu Ser Pro Cys Pro  Val Gly Glu Pro Pro  Leu Ala Leu 
    1265                 1270                 1275             


Glu Asn  Ala Ala Ser Leu Lys  Leu Phe Ala Gly Ser  Leu Ala Pro 
    1280                 1285                 1290             


Leu Leu  Gln Pro Gly Ala Ala  Gly Gly Glu Ile Pro  Ala Val Gln 
    1295                 1300                 1305             


Ala Ser  Ser Gly Ser Pro Lys  Ala Arg Thr Thr Glu  Gly Pro Val 
    1310                 1315                 1320             


Asp Ser  Met Pro Cys Leu Asp  Arg Met Pro Leu Leu  Ala Lys Gly 
    1325                 1330                 1335             


Lys Gln  Ala Thr Gly Glu Glu  Lys Ala Ala Thr Ala  Pro Gly Ala 
    1340                 1345                 1350             


Gly Ala  Lys Ala Ser Gly Glu  Gly Met Ala Gly Asp  Ala Ala Gly 
    1355                 1360                 1365             


Glu Thr  Glu Gly Ser Met Glu  Arg Met Gly Glu Pro  Ser Gln Asp 
    1370                 1375                 1380             


Pro Lys  Gln Gly Thr Ser Gly  Gly Val Asp Thr Ser  Ser Glu Gln 
    1385                 1390                 1395             


Ile Ala  Thr Leu Thr Gly Phe  Pro Asp Phe Arg Glu  His Ile Ala 
    1400                 1405                 1410             


Lys Ile  Phe Glu Lys Pro Val  Leu Gly Ala Leu Ala  Thr Pro Gly 
    1415                 1420                 1425             


Glu Lys  Ala Gly Ala Gly Arg  Ser Ala Val Gly Lys  Asp Leu Thr 
    1430                 1435                 1440             


Arg Pro  Leu Gly Pro Glu Lys  Leu Leu Asp Gly Pro  Pro Gly Val 
    1445                 1450                 1455             


Asp Val  Thr Leu Leu Pro Ala  Pro Pro Ala Arg Leu  Gln Val Glu 
    1460                 1465                 1470             


Lys Lys  Gln Gln Leu Ala Gly  Glu Ala Glu Ile Ser  His Leu Ala 
    1475                 1480                 1485             


Leu Gln  Asp Pro Ala Ser Asp  Lys Leu Leu Gly Pro  Ala Gly Leu 
    1490                 1495                 1500             


Thr Trp  Glu Arg Asn Leu Pro  Gly Ala Gly Val Gly  Lys Glu Met 
    1505                 1510                 1515             


Ala Gly  Val Pro Pro Thr Leu  Arg Glu Asp Glu Arg  Pro Glu Gly 
    1520                 1525                 1530             


Pro Gly  Ala Ala Trp Pro Gly  Leu Glu Gly Gln Ala  Tyr Ser Gln 
    1535                 1540                 1545             


Leu Glu  Arg Ser Arg Gln Glu  Leu Ala Ser Gly Leu  Pro Ser Pro 
    1550                 1555                 1560             


Ala Ala  Thr Gln Glu Leu Pro  Val Glu Arg Ala Ala  Ala Phe Gln 
    1565                 1570                 1575             


Val Ala  Pro His Ser His Gly  Glu Glu Ala Val Ala  Gln Asp Arg 
    1580                 1585                 1590             


Ile Pro  Ser Gly Lys Gln His  Gln Glu Thr Ser Ala  Cys Asp Ser 
    1595                 1600                 1605             


Pro His  Gly Glu Asp Gly Pro  Gly Asp Phe Ala His  Thr Gly Val 
    1610                 1615                 1620             


Pro Gly  His Val Pro Arg Ser  Thr Cys Ala Pro Ser  Pro Gln Arg 
    1625                 1630                 1635             


Glu Val  Leu Thr Val Pro Glu  Ala Asn Ser Glu Pro  Trp Thr Leu 
    1640                 1645                 1650             


Asp Thr  Leu Gly Gly Glu Arg  Arg Pro Gly Val Thr  Ala Gly Ile 
    1655                 1660                 1665             


Leu Glu  Met Arg Asn Ala Leu  Gly Asn Gln Ser Thr  Pro Ala Pro 
    1670                 1675                 1680             


Pro Thr  Gly Glu Val Ala Asp  Thr Pro Leu Glu Pro  Gly Lys Val 
    1685                 1690                 1695             


Ala Gly  Ala Ala Gly Glu Ala  Glu Gly Asp Ile Thr  Leu Ser Thr 
    1700                 1705                 1710             


Ala Glu  Thr Gln Ala Cys Ala  Ser Gly Asp Leu Pro  Glu Ala Gly 
    1715                 1720                 1725             


Thr Thr  Arg Thr Phe Ser Val  Val Ala Gly Asp Leu  Val Leu Pro 
    1730                 1735                 1740             


Gly Ser  Cys Gln Asp Pro Ala  Cys Ser Asp Lys Ala  Pro Gly Met 
    1745                 1750                 1755             


Glu Gly  Thr Ala Ala Leu His  Gly Asp Ser Pro Ala  Arg Pro Gln 
    1760                 1765                 1770             


Gln Ala  Lys Glu Gln Pro Gly  Pro Glu Arg Pro Ile  Pro Ala Gly 
    1775                 1780                 1785             


Asp Gly  Lys Val Cys Val Ser  Ser Pro Pro Glu Pro  Asp Glu Thr 
    1790                 1795                 1800             


His Asp  Pro Lys Leu Gln His  Leu Ala Pro Glu Glu  Leu His Thr 
    1805                 1810                 1815             


Asp Arg  Glu Ser Pro Arg Pro  Gly Pro Ser Met Leu  Pro Ser Val 
    1820                 1825                 1830             


Pro Lys  Lys Asp Ala Pro Arg  Val Met Asp Lys Val  Thr Ser Asp 
    1835                 1840                 1845             


Glu Thr  Arg Gly Ala Glu Gly  Thr Glu Ser Ser Pro  Val Ala Asp 
    1850                 1855                 1860             


Asp Ile  Ile Gln Pro Ala Ala  Pro Ala Asp Leu Glu  Ser Pro Thr 
    1865                 1870                 1875             


Leu Ala  Ala Ser Ser Tyr His  Gly Asp Val Val Gly  Gln Val Ser 
    1880                 1885                 1890             


Thr Asp  Leu Ile Ala Gln Ser  Ile Ser Pro Ala Ala  Ala His Ala 
    1895                 1900                 1905             


Gly Leu  Pro Pro Ser Ala Ala  Glu His Ile Val Ser  Pro Ser Ala 
    1910                 1915                 1920             


Pro Ala  Gly Asp Arg Val Glu  Ala Ser Thr Pro Ser  Cys Pro Asp 
    1925                 1930                 1935             


Pro Ala  Lys Asp Leu Ser Arg  Ser Ser Asp Ser Glu  Glu Ala Phe 
    1940                 1945                 1950             


Glu Thr  Pro Glu Ser Thr Thr  Pro Val Lys Ala Pro  Pro Ala Pro 
    1955                 1960                 1965             


Pro Pro  Pro Pro Pro Glu Val  Ile Pro Glu Pro Glu  Val Ser Thr 
    1970                 1975                 1980             


Gln Pro  Pro Pro Glu Glu Pro  Gly Cys Gly Ser Glu  Thr Val Pro 
    1985                 1990                 1995             


Val Pro  Asp Gly Pro Arg Ser  Asp Ser Val Glu Gly  Ser Pro Phe 
    2000                 2005                 2010             


Arg Pro  Pro Ser His Ser Phe  Ser Ala Val Phe Asp  Glu Asp Lys 
    2015                 2020                 2025             


Pro Ile  Ala Ser Ser Gly Thr  Tyr Asn Leu Asp Phe  Asp Asn Ile 
    2030                 2035                 2040             


Glu Leu  Val Asp Thr Phe Gln  Thr Leu Glu Pro Arg  Ala Ser Asp 
    2045                 2050                 2055             


Ala Lys  Asn Gln Glu Gly Lys  Val Asn Thr Arg Arg  Lys Ser Thr 
    2060                 2065                 2070             


Asp Ser  Val Pro Ile Ser Lys  Ser Thr Leu Ser Arg  Ser Leu Ser 
    2075                 2080                 2085             


Leu Gln  Ala Ser Asp Phe Asp  Gly Ala Ser Ser Ser  Gly Asn Pro 
    2090                 2095                 2100             


Glu Ala  Val Ala Leu Ala Pro  Asp Ala Tyr Ser Thr  Gly Ser Ser 
    2105                 2110                 2115             


Ser Ala  Ser Ser Thr Leu Lys  Arg Thr Lys Lys Pro  Arg Pro Pro 
    2120                 2125                 2130             


Ser Leu  Lys Lys Lys Gln Thr  Thr Lys Lys Pro Thr  Glu Thr Pro 
    2135                 2140                 2145             


Pro Val  Lys Glu Thr Gln Gln  Glu Pro Asp Glu Glu  Ser Leu Val 
    2150                 2155                 2160             


Pro Ser  Gly Glu Asn Leu Ala  Ser Glu Thr Lys Thr  Glu Ser Ala 
    2165                 2170                 2175             


Lys Thr  Glu Gly Pro Ser Pro  Ala Leu Leu Glu Glu  Thr Pro Leu 
    2180                 2185                 2190             


Glu Pro  Ala Val Gly Pro Lys  Ala Ala Cys Pro Leu  Asp Ser Glu 
    2195                 2200                 2205             


Ser Ala  Glu Gly Val Val Pro  Pro Ala Ser Gly Gly  Gly Arg Val 
    2210                 2215                 2220             


Gln Asn  Ser Pro Pro Val Gly  Arg Lys Thr Leu Pro  Leu Thr Thr 
    2225                 2230                 2235             


Ala Pro  Glu Ala Gly Glu Val  Thr Pro Ser Asp Ser  Gly Gly Gln 
    2240                 2245                 2250             


Glu Asp  Ser Pro Ala Lys Gly  Leu Ser Val Arg Leu  Glu Phe Asp 
    2255                 2260                 2265             


Tyr Ser  Glu Asp Lys Ser Ser  Trp Asp Asn Gln Gln  Glu Asn Pro 
    2270                 2275                 2280             


Pro Pro  Thr Lys Lys Ile Gly  Lys Lys Pro Val Ala  Lys Met Pro 
    2285                 2290                 2295             


Leu Arg  Arg Pro Lys Met Lys  Lys Thr Pro Glu Lys  Leu Asp Asn 
    2300                 2305                 2310             


Thr Pro  Ala Ser Pro Pro Arg  Ser Pro Ala Glu Pro  Asn Asp Ile 
    2315                 2320                 2325             


Pro Ile  Ala Lys Gly Thr Tyr  Thr Phe Asp Ile Asp  Lys Trp Asp 
    2330                 2335                 2340             


Asp Pro  Asn Phe Asn Pro Phe  Ser Ser Thr Ser Lys  Met Gln Glu 
    2345                 2350                 2355             


Ser Pro  Lys Leu Pro Gln Gln  Ser Tyr Asn Phe Asp  Pro Asp Thr 
    2360                 2365                 2370             


Cys Asp  Glu Ser Val Asp Pro  Phe Lys Thr Ser Ser  Lys Thr Pro 
    2375                 2380                 2385             


Ser Ser  Pro Ser Lys Ser Pro  Ala Ser Phe Glu Ile  Pro Ala Ser 
    2390                 2395                 2400             


Ala Met  Glu Ala Asn Gly Val  Asp Gly Asp Gly Leu  Asn Lys Pro 
    2405                 2410                 2415             


Ala Lys  Lys Lys Lys Thr Pro  Leu Lys Thr Asp Thr  Phe Arg Val 
    2420                 2425                 2430             


Lys Lys  Ser Pro Lys Arg Ser  Pro Leu Ser Asp Pro  Pro Ser Gln 
    2435                 2440                 2445             


Asp Pro  Thr Pro Ala Ala Thr  Pro Glu Thr Pro Pro  Val Ile Ser 
    2450                 2455                 2460             


Ala Val  Val His Ala Thr Asp  Glu Glu Lys Leu Ala  Val Thr Asn 
    2465                 2470                 2475             


Gln Lys  Trp Thr Cys Met Thr  Val Asp Leu Glu Ala  Asp Lys Gln 
    2480                 2485                 2490             


Asp Tyr  Pro Gln Pro Ser Asp  Leu Ser Thr Phe Val  Asn Glu Thr 
    2495                 2500                 2505             


Lys Phe  Ser Ser Pro Thr Glu  Glu Leu Asp Tyr Arg  Asn Ser Tyr 
    2510                 2515                 2520             


Glu Ile  Glu Tyr Met Glu Lys  Ile Gly Ser Ser Leu  Pro Gln Asp 
    2525                 2530                 2535             


Asp Asp  Ala Pro Lys Lys Gln  Ala Leu Tyr Leu Met  Phe Asp Thr 
    2540                 2545                 2550             


Ser Gln  Glu Ser Pro Val Lys  Ser Ser Pro Val Arg  Met Ser Glu 
    2555                 2560                 2565             


Ser Pro  Thr Pro Cys Ser Gly  Ser Ser Phe Glu Glu  Thr Glu Ala 
    2570                 2575                 2580             


Leu Val  Asn Thr Ala Ala Lys  Asn Gln His Pro Val  Pro Arg Gly 
    2585                 2590                 2595             


Leu Ala  Pro Asn Gln Glu Ser  His Leu Gln Val Pro  Glu Lys Ser 
    2600                 2605                 2610             


Ser Gln  Lys Glu Leu Glu Ala  Met Gly Leu Gly Thr  Pro Ser Glu 
    2615                 2620                 2625             


Ala Ile  Glu Ile Thr Ala Pro  Glu Gly Ser Phe Ala  Ser Ala Asp 
    2630                 2635                 2640             


Ala Leu  Leu Ser Arg Leu Ala  His Pro Val Ser Leu  Cys Gly Ala 
    2645                 2650                 2655             


Leu Asp  Tyr Leu Glu Pro Asp  Leu Ala Glu Lys Asn  Pro Pro Leu 
    2660                 2665                 2670             


Phe Ala  Gln Lys Leu Gln Glu  Glu Leu Glu Phe Ala  Ile Met Arg 
    2675                 2680                 2685             


Ile Glu  Ala Leu Lys Leu Ala  Arg Gln Ile Ala Leu  Ala Ser Arg 
    2690                 2695                 2700             


Ser His  Gln Asp Ala Lys Arg  Glu Ala Ala His Pro  Thr Asp Val 
    2705                 2710                 2715             


Ser Ile  Ser Lys Thr Ala Leu  Tyr Ser Arg Ile Gly  Thr Ala Glu 
    2720                 2725                 2730             


Val Glu  Lys Pro Ala Gly Leu  Leu Phe Gln Gln Pro  Asp Leu Asp 
    2735                 2740                 2745             


Ser Ala  Leu Gln Ile Ala Arg  Ala Glu Ile Ile Thr  Lys Glu Arg 
    2750                 2755                 2760             


Glu Val  Ser Glu Trp Lys Asp  Lys Tyr Glu Glu Ser  Arg Arg Glu 
    2765                 2770                 2775             


Val Met  Glu Met Arg Lys Ile  Val Ala Glu Tyr Glu  Lys Thr Ile 
    2780                 2785                 2790             


Ala Gln  Met Ile Glu Asp Glu  Gln Arg Glu Lys Ser  Val Ser His 
    2795                 2800                 2805             


Gln Thr  Val Gln Gln Leu Val  Leu Glu Lys Glu Gln  Ala Leu Ala 
    2810                 2815                 2820             


Asp Leu  Asn Ser Val Glu Lys  Ser Leu Ala Asp Leu  Phe Arg Arg 
    2825                 2830                 2835             


Tyr Glu  Lys Met Lys Glu Val  Leu Glu Gly Phe Arg  Lys Asn Glu 
    2840                 2845                 2850             


Glu Val  Leu Lys Arg Cys Ala  Gln Glu Tyr Leu Ser  Arg Val Lys 
    2855                 2860                 2865             


Lys Glu  Glu Gln Arg Tyr Gln  Ala Leu Lys Val His  Ala Glu Glu 
    2870                 2875                 2880             


Lys Leu  Asp Arg Ala Asn Ala  Glu Ile Ala Gln Val  Arg Gly Lys 
    2885                 2890                 2895             


Ala Gln  Gln Glu Gln Ala Ala  His Gln Ala Ser Leu  Arg Lys Glu 
    2900                 2905                 2910             


Gln Leu  Arg Val Asp Ala Leu  Glu Arg Thr Leu Glu  Gln Lys Asn 
    2915                 2920                 2925             


Lys Glu  Ile Glu Glu Leu Thr  Lys Ile Cys Asp Glu  Leu Ile Ala 
    2930                 2935                 2940             


Lys Met  Gly Lys Ser 
    2945             


<210>  3955
<211>  670
<212>  PRT
<213>  homo sapiens

<400>  3955

Met Gly Glu Pro Ala Gly Val Ala Gly Thr Met Glu Ser Pro Phe Ser 
1               5                   10                  15      


Pro Gly Leu Phe His Arg Leu Asp Glu Asp Trp Asp Ser Ala Leu Phe 
            20                  25                  30          


Ala Glu Leu Gly Tyr Phe Thr Asp Thr Asp Glu Leu Gln Leu Glu Ala 
        35                  40                  45              


Ala Asn Glu Thr Tyr Glu Asn Asn Phe Asp Asn Leu Asp Phe Asp Leu 
    50                  55                  60                  


Asp Leu Met Pro Trp Glu Ser Asp Ile Trp Asp Ile Asn Asn Gln Ile 
65                  70                  75                  80  


Cys Thr Val Lys Asp Ile Lys Ala Glu Pro Gln Pro Leu Ser Pro Ala 
                85                  90                  95      


Ser Ser Ser Tyr Ser Val Ser Ser Pro Arg Ser Val Asp Ser Tyr Ser 
            100                 105                 110         


Ser Thr Gln His Val Pro Glu Glu Leu Asp Leu Ser Ser Ser Ser Gln 
        115                 120                 125             


Met Ser Pro Leu Ser Leu Tyr Gly Glu Asn Ser Asn Ser Leu Ser Ser 
    130                 135                 140                 


Ala Glu Pro Leu Lys Glu Asp Lys Pro Val Thr Gly Pro Arg Asn Lys 
145                 150                 155                 160 


Thr Glu Asn Gly Leu Thr Pro Lys Lys Lys Ile Gln Val Asn Ser Lys 
                165                 170                 175     


Pro Ser Ile Gln Pro Lys Pro Leu Leu Leu Pro Ala Ala Pro Lys Thr 
            180                 185                 190         


Gln Thr Asn Ser Ser Val Pro Ala Lys Thr Ile Ile Ile Gln Thr Val 
        195                 200                 205             


Pro Thr Leu Met Pro Leu Ala Lys Gln Gln Pro Ile Ile Ser Leu Gln 
    210                 215                 220                 


Pro Ala Pro Thr Lys Gly Gln Thr Val Leu Leu Ser Gln Pro Thr Val 
225                 230                 235                 240 


Val Gln Leu Gln Ala Pro Gly Val Leu Pro Ser Ala Gln Pro Val Leu 
                245                 250                 255     


Ala Val Ala Gly Gly Val Thr Gln Leu Pro Asn His Val Val Asn Val 
            260                 265                 270         


Val Pro Ala Pro Ser Ala Asn Ser Pro Val Asn Gly Lys Leu Ser Val 
        275                 280                 285             


Thr Lys Pro Val Leu Gln Ser Thr Met Arg Asn Val Gly Ser Asp Ile 
    290                 295                 300                 


Ala Val Leu Arg Arg Gln Gln Arg Met Ile Lys Asn Arg Glu Ser Ala 
305                 310                 315                 320 


Cys Gln Ser Arg Lys Lys Lys Lys Glu Tyr Met Leu Gly Leu Glu Ala 
                325                 330                 335     


Arg Leu Lys Ala Ala Leu Ser Glu Asn Glu Gln Leu Lys Lys Glu Asn 
            340                 345                 350         


Gly Thr Leu Lys Arg Gln Leu Asp Glu Val Val Ser Glu Asn Gln Arg 
        355                 360                 365             


Leu Lys Val Pro Ser Pro Lys Arg Arg Val Val Cys Val Met Ile Val 
    370                 375                 380                 


Leu Ala Phe Ile Ile Leu Asn Tyr Gly Pro Met Ser Met Leu Glu Gln 
385                 390                 395                 400 


Asp Ser Arg Arg Met Asn Pro Ser Val Ser Pro Ala Asn Gln Arg Arg 
                405                 410                 415     


His Leu Leu Gly Phe Ser Ala Lys Glu Ala Gln Asp Thr Ser Asp Gly 
            420                 425                 430         


Ile Ile Gln Lys Asn Ser Tyr Arg Tyr Asp His Ser Val Ser Asn Asp 
        435                 440                 445             


Lys Ala Leu Met Val Leu Thr Glu Glu Pro Leu Leu Tyr Ile Pro Pro 
    450                 455                 460                 


Pro Pro Cys Gln Pro Leu Ile Asn Thr Thr Glu Ser Leu Arg Leu Asn 
465                 470                 475                 480 


His Glu Leu Arg Gly Trp Val His Arg His Glu Val Glu Arg Thr Lys 
                485                 490                 495     


Ser Arg Arg Met Thr Asn Asn Gln Gln Lys Thr Arg Ile Leu Gln Gly 
            500                 505                 510         


Ala Leu Glu Gln Gly Ser Asn Ser Gln Leu Met Ala Val Gln Tyr Thr 
        515                 520                 525             


Glu Thr Thr Ser Ser Ile Ser Arg Asn Ser Gly Ser Glu Leu Gln Val 
    530                 535                 540                 


Tyr Tyr Ala Ser Pro Arg Ser Tyr Gln Asp Phe Phe Glu Ala Ile Arg 
545                 550                 555                 560 


Arg Arg Gly Asp Thr Phe Tyr Val Val Ser Phe Arg Arg Asp His Leu 
                565                 570                 575     


Leu Leu Pro Ala Thr Thr His Asn Lys Thr Thr Arg Pro Lys Met Ser 
            580                 585                 590         


Ile Val Leu Pro Ala Ile Asn Ile Asn Glu Asn Val Ile Asn Gly Gln 
        595                 600                 605             


Asp Tyr Glu Val Met Met Gln Ile Asp Cys Gln Val Met Asp Thr Arg 
    610                 615                 620                 


Ile Leu His Ile Lys Ser Ser Ser Val Pro Pro Tyr Leu Arg Asp Gln 
625                 630                 635                 640 


Gln Arg Asn Gln Thr Asn Thr Phe Phe Gly Ser Pro Pro Ala Ala Thr 
                645                 650                 655     


Glu Ala Thr His Val Val Ser Thr Ile Pro Glu Ser Leu Gln 
            660                 665                 670 


<210>  3956
<211>  446
<212>  PRT
<213>  homo sapiens

<400>  3956

Met Leu Asp Met Ser Glu Ala Arg Ser Gln Pro Pro Cys Ser Pro Ser 
1               5                   10                  15      


Gly Thr Ala Ser Ser Met Ser His Val Glu Asp Ser Asp Ser Asp Ala 
            20                  25                  30          


Pro Pro Ser Pro Ala Gly Ser Glu Gly Leu Gly Arg Ala Gly Val Ala 
        35                  40                  45              


Val Gly Gly Ala Arg Gly Asp Pro Ala Glu Ala Ala Asp Glu Arg Phe 
    50                  55                  60                  


Pro Ala Cys Ile Arg Asp Ala Val Ser Gln Val Leu Lys Gly Tyr Asp 
65                  70                  75                  80  


Trp Ser Leu Val Pro Met Pro Val Arg Gly Gly Gly Gly Gly Ala Leu 
                85                  90                  95      


Lys Ala Lys Pro His Val Lys Arg Pro Met Asn Ala Phe Met Val Trp 
            100                 105                 110         


Ala Gln Ala Ala Arg Arg Lys Leu Ala Asp Gln Tyr Pro His Leu His 
        115                 120                 125             


Asn Ala Glu Leu Ser Lys Thr Leu Gly Lys Leu Trp Arg Leu Leu Ser 
    130                 135                 140                 


Glu Ser Glu Lys Arg Pro Phe Val Glu Glu Ala Glu Arg Leu Arg Val 
145                 150                 155                 160 


Gln His Lys Lys Asp His Pro Asp Tyr Lys Tyr Gln Pro Arg Arg Arg 
                165                 170                 175     


Lys Ser Ala Lys Ala Gly His Ser Asp Ser Asp Ser Gly Ala Glu Leu 
            180                 185                 190         


Gly Pro His Pro Gly Gly Gly Ala Val Tyr Lys Ala Glu Ala Gly Leu 
        195                 200                 205             


Gly Asp Gly His His His Gly Asp His Thr Gly Gln Thr His Gly Pro 
    210                 215                 220                 


Pro Thr Pro Pro Thr Thr Pro Lys Thr Glu Leu Gln Gln Ala Gly Ala 
225                 230                 235                 240 


Lys Pro Glu Leu Lys Leu Glu Gly Arg Arg Pro Val Asp Ser Gly Arg 
                245                 250                 255     


Gln Asn Ile Asp Phe Ser Asn Val Asp Ile Ser Glu Leu Ser Ser Glu 
            260                 265                 270         


Val Met Gly Thr Met Asp Ala Phe Asp Val His Glu Phe Asp Gln Tyr 
        275                 280                 285             


Leu Pro Leu Gly Gly Pro Ala Pro Pro Glu Pro Gly Gln Ala Tyr Gly 
    290                 295                 300                 


Gly Ala Tyr Phe His Ala Gly Ala Ser Pro Val Trp Ala His Lys Ser 
305                 310                 315                 320 


Ala Pro Ser Ala Ser Ala Ser Pro Thr Glu Thr Gly Pro Pro Arg Pro 
                325                 330                 335     


His Ile Lys Thr Glu Gln Pro Ser Pro Gly His Tyr Gly Asp Gln Pro 
            340                 345                 350         


Arg Gly Ser Pro Asp Tyr Gly Ser Cys Ser Gly Gln Ser Ser Ala Thr 
        355                 360                 365             


Pro Ala Ala Pro Ala Gly Pro Phe Ala Gly Ser Gln Gly Asp Tyr Gly 
    370                 375                 380                 


Asp Leu Gln Ala Ser Ser Tyr Tyr Gly Ala Tyr Pro Gly Tyr Ala Pro 
385                 390                 395                 400 


Gly Leu Tyr Gln Tyr Pro Cys Phe His Ser Pro Arg Arg Pro Tyr Ala 
                405                 410                 415     


Ser Pro Leu Leu Asn Gly Leu Ala Leu Pro Pro Ala His Ser Pro Thr 
            420                 425                 430         


Ser His Trp Asp Gln Pro Val Tyr Thr Thr Leu Thr Arg Pro 
        435                 440                 445     


<210>  3957
<211>  1224
<212>  PRT
<213>  homo sapiens

<400>  3957

Met Leu Pro Tyr Thr Val Asn Phe Lys Val Ser Ala Arg Thr Leu Thr 
1               5                   10                  15      


Gly Ala Leu Asn Ala His Asn Lys Ala Ala Val Asp Trp Gly Trp Gln 
            20                  25                  30          


Gly Leu Ile Ala Tyr Gly Cys His Ser Leu Val Val Val Ile Asp Ser 
        35                  40                  45              


Ile Thr Ala Gln Thr Leu Gln Val Leu Glu Lys His Lys Ala Asp Val 
    50                  55                  60                  


Val Lys Val Lys Trp Ala Arg Glu Asn Tyr His His Asn Ile Gly Ser 
65                  70                  75                  80  


Pro Tyr Cys Leu Arg Leu Ala Ser Ala Asp Val Asn Gly Lys Ile Ile 
                85                  90                  95      


Val Trp Asp Val Ala Ala Gly Val Ala Gln Cys Glu Ile Gln Glu His 
            100                 105                 110         


Ala Lys Pro Ile Gln Asp Val Gln Trp Leu Trp Asn Gln Asp Ala Ser 
        115                 120                 125             


Arg Asp Leu Leu Leu Ala Ile His Pro Pro Asn Tyr Ile Val Leu Trp 
    130                 135                 140                 


Asn Ala Asp Thr Gly Thr Lys Leu Trp Lys Lys Ser Tyr Ala Asp Asn 
145                 150                 155                 160 


Ile Leu Ser Phe Ser Phe Asp Pro Phe Asp Pro Ser His Leu Thr Leu 
                165                 170                 175     


Leu Thr Ser Glu Gly Ile Val Phe Ile Ser Asp Phe Ser Pro Ser Lys 
            180                 185                 190         


Pro Pro Ser Gly Pro Gly Lys Lys Val Tyr Ile Ser Ser Pro His Ser 
        195                 200                 205             


Ser Pro Ala His Asn Lys Leu Ala Thr Ala Thr Gly Ala Lys Lys Ala 
    210                 215                 220                 


Leu Asn Lys Val Lys Ile Leu Ile Thr Gln Glu Lys Pro Ser Ala Glu 
225                 230                 235                 240 


Phe Ile Thr Leu Asn Asp Cys Leu Gln Leu Ala Tyr Leu Pro Ser Lys 
                245                 250                 255     


Arg Asn His Met Leu Leu Leu Tyr Pro Arg Glu Ile Leu Ile Leu Asp 
            260                 265                 270         


Leu Glu Val Asn Gln Thr Val Gly Val Ile Ala Ile Glu Arg Thr Gly 
        275                 280                 285             


Val Pro Phe Leu Gln Val Ile Pro Cys Phe Gln Arg Asp Gly Leu Phe 
    290                 295                 300                 


Cys Leu His Glu Asn Gly Cys Ile Thr Leu Arg Val Arg Arg Ser Tyr 
305                 310                 315                 320 


Asn Asn Ile Phe Thr Thr Ser Asn Glu Glu Pro Asp Pro Asp Pro Val 
                325                 330                 335     


Gln Glu Leu Thr Tyr Asp Leu Arg Ser Gln Cys Asp Ala Ile Arg Val 
            340                 345                 350         


Thr Lys Thr Val Arg Pro Phe Ser Met Val Cys Cys Pro Val Asn Glu 
        355                 360                 365             


Asn Ala Ala Ala Leu Val Val Ser Asp Gly Arg Val Met Ile Trp Glu 
    370                 375                 380                 


Leu Lys Ser Ala Val Cys Asn Arg Asn Ser Arg Asn Ser Ser Ser Gly 
385                 390                 395                 400 


Val Ser Pro Leu Tyr Ser Pro Val Ser Phe Cys Gly Ile Pro Val Gly 
                405                 410                 415     


Val Leu Gln Asn Lys Leu Pro Asp Leu Ser Leu Asp Asn Met Ile Gly 
            420                 425                 430         


Gln Ser Ala Ile Ala Gly Glu Glu His Pro Arg Gly Ser Ile Leu Arg 
        435                 440                 445             


Glu Val His Leu Lys Phe Leu Leu Thr Gly Leu Leu Ser Gly Leu Pro 
    450                 455                 460                 


Ala Pro Gln Phe Ala Ile Arg Met Cys Pro Pro Leu Thr Thr Lys Asn 
465                 470                 475                 480 


Ile Lys Met Tyr Gln Pro Leu Leu Ala Val Gly Thr Ser Asn Gly Ser 
                485                 490                 495     


Val Leu Val Tyr His Leu Thr Ser Gly Leu Leu His Lys Glu Leu Ser 
            500                 505                 510         


Ile His Ser Cys Glu Val Lys Gly Ile Glu Trp Thr Ser Leu Thr Ser 
        515                 520                 525             


Phe Leu Ser Phe Ala Thr Ser Thr Pro Asn Asn Met Gly Leu Val Arg 
    530                 535                 540                 


Asn Glu Leu Gln Leu Val Asp Leu Pro Thr Gly Arg Ser Ile Ala Phe 
545                 550                 555                 560 


Arg Gly Glu Arg Gly Asn Asp Glu Ser Ala Ile Glu Met Ile Lys Val 
                565                 570                 575     


Ser His Leu Lys Gln Tyr Leu Ala Val Val Phe Arg Asp Lys Pro Leu 
            580                 585                 590         


Glu Leu Trp Asp Val Arg Thr Cys Thr Leu Leu Arg Glu Met Ser Lys 
        595                 600                 605             


Asn Phe Pro Thr Ile Thr Ala Leu Glu Trp Ser Pro Ser His Asn Leu 
    610                 615                 620                 


Lys Ser Leu Arg Lys Lys Gln Leu Ala Thr Arg Glu Ala Met Ala Arg 
625                 630                 635                 640 


Gln Thr Val Val Ser Asp Thr Glu Leu Ser Ile Val Glu Ser Ser Val 
                645                 650                 655     


Ile Ser Leu Leu Gln Glu Ala Glu Ser Lys Ser Glu Leu Ser Gln Asn 
            660                 665                 670         


Ile Ser Ala Arg Glu His Phe Val Phe Thr Asp Ile Asp Gly Gln Val 
        675                 680                 685             


Tyr His Leu Thr Val Glu Gly Asn Ser Val Lys Asp Ser Ala Arg Ile 
    690                 695                 700                 


Pro Pro Asp Gly Ser Met Gly Ser Ile Thr Cys Ile Ala Trp Lys Gly 
705                 710                 715                 720 


Asp Thr Leu Val Leu Gly Asp Met Asp Gly Asn Leu Asn Phe Trp Asp 
                725                 730                 735     


Leu Lys Gly Arg Val Ser Arg Gly Ile Pro Thr His Arg Ser Trp Val 
            740                 745                 750         


Arg Lys Ile Arg Phe Ala Pro Gly Lys Gly Asn Gln Lys Leu Ile Ala 
        755                 760                 765             


Met Tyr Asn Asp Gly Ala Glu Val Trp Asp Thr Lys Glu Val Gln Met 
    770                 775                 780                 


Val Ser Ser Leu Arg Ser Gly Arg Asn Val Thr Phe Arg Ile Leu Asp 
785                 790                 795                 800 


Val Asp Trp Cys Thr Ser Asp Lys Val Ile Leu Ala Ser Asp Asp Gly 
                805                 810                 815     


Cys Ile Arg Val Leu Glu Met Ser Met Lys Ser Ala Cys Phe Arg Met 
            820                 825                 830         


Asp Glu Gln Glu Leu Thr Glu Pro Val Trp Cys Pro Tyr Leu Leu Val 
        835                 840                 845             


Pro Arg Ala Ser Leu Ala Leu Lys Ala Phe Leu Leu His Gln Pro Trp 
    850                 855                 860                 


Asn Gly Gln Tyr Ser Leu Asp Ile Ser His Val Asp Tyr Pro Glu Asn 
865                 870                 875                 880 


Glu Glu Ile Lys Asn Leu Leu Gln Glu Gln Leu Asn Ser Leu Ser Asn 
                885                 890                 895     


Asp Ile Lys Lys Leu Leu Leu Asp Pro Glu Phe Thr Leu Leu Gln Arg 
            900                 905                 910         


Cys Leu Leu Val Ser Arg Leu Tyr Gly Asp Glu Ser Glu Leu His Phe 
        915                 920                 925             


Trp Thr Val Ala Ala His Tyr Leu His Ser Leu Ser Gln Glu Lys Ser 
    930                 935                 940                 


Ala Ser Thr Thr Ala Pro Lys Glu Ala Ala Pro Arg Asp Lys Leu Ser 
945                 950                 955                 960 


Asn Pro Leu Asp Ile Cys Tyr Asp Val Leu Cys Glu Asn Ala Tyr Phe 
                965                 970                 975     


Gln Lys Phe Gln Leu Glu Arg Val Asn Leu Gln Glu Val Lys Arg Ser 
            980                 985                 990         


Thr Tyr Asp His Thr Arg Lys Cys  Thr Asp Gln Leu Leu  Leu Leu Gly 
        995                 1000                 1005             


Gln Thr  Asp Arg Ala Val Gln  Leu Leu Leu Glu Thr  Ser Ala Asp 
    1010                 1015                 1020             


Asn Gln  His Tyr Tyr Cys Asp  Ser Leu Lys Ala Cys  Leu Val Thr 
    1025                 1030                 1035             


Thr Val  Thr Ser Ser Gly Pro  Ser Gln Ser Thr Ile  Lys Leu Val 
    1040                 1045                 1050             


Ala Thr  Asn Met Ile Ala Asn  Gly Lys Leu Ala Glu  Gly Val Gln 
    1055                 1060                 1065             


Leu Leu  Cys Leu Ile Asp Lys  Ala Ala Asp Ala Cys  Arg Tyr Leu 
    1070                 1075                 1080             


Gln Thr  Tyr Gly Glu Trp Asn  Arg Ala Ala Trp Leu  Ala Lys Val 
    1085                 1090                 1095             


Arg Leu  Asn Pro Glu Glu Cys  Ala Asp Val Leu Arg  Arg Trp Val 
    1100                 1105                 1110             


Asp His  Leu Cys Ser Pro Gln  Val Asn Gln Lys Ser  Lys Ala Leu 
    1115                 1120                 1125             


Leu Val  Leu Leu Ser Leu Gly  Cys Phe Phe Ser Val  Ala Glu Thr 
    1130                 1135                 1140             


Leu His  Ser Met Arg Tyr Phe  Asp Arg Ala Ala Leu  Phe Val Glu 
    1145                 1150                 1155             


Ala Cys  Leu Lys Tyr Gly Ala  Phe Glu Val Thr Glu  Asp Thr Glu 
    1160                 1165                 1170             


Lys Leu  Ile Thr Ala Ile Tyr  Ala Asp Tyr Ala Arg  Ser Leu Lys 
    1175                 1180                 1185             


Asn Leu  Gly Phe Lys Gln Gly  Ala Val Leu Phe Ala  Ser Lys Ala 
    1190                 1195                 1200             


Gly Ala  Ala Gly Lys Asp Leu  Leu Asn Glu Leu Glu  Ser Pro Lys 
    1205                 1210                 1215             


Glu Glu  Pro Ile Glu Glu 
    1220                 


<210>  3958
<211>  830
<212>  PRT
<213>  homo sapiens

<400>  3958

Met Val Glu Glu Glu Asn Ile Arg Val Val Arg Cys Gly Gly Ser Glu 
1               5                   10                  15      


Leu Asn Phe Arg Arg Ala Val Phe Ser Ala Asp Ser Lys Tyr Ile Phe 
            20                  25                  30          


Cys Val Ser Gly Asp Phe Val Lys Val Tyr Ser Thr Val Thr Glu Glu 
        35                  40                  45              


Cys Val His Ile Leu His Gly His Arg Asn Leu Val Thr Gly Ile Gln 
    50                  55                  60                  


Leu Asn Pro Asn Asn His Leu Gln Leu Tyr Ser Cys Ser Leu Asp Gly 
65                  70                  75                  80  


Thr Ile Lys Leu Trp Asp Tyr Ile Asp Gly Ile Leu Ile Lys Thr Phe 
                85                  90                  95      


Ile Val Gly Cys Lys Leu His Ala Leu Phe Thr Leu Ala Gln Ala Glu 
            100                 105                 110         


Asp Ser Val Phe Val Ile Val Asn Lys Glu Lys Pro Asp Ile Phe Gln 
        115                 120                 125             


Leu Val Ser Val Lys Leu Pro Lys Ser Ser Ser Gln Glu Val Glu Ala 
    130                 135                 140                 


Lys Glu Leu Ser Phe Val Leu Asp Tyr Ile Asn Gln Ser Pro Lys Cys 
145                 150                 155                 160 


Ile Ala Phe Gly Asn Glu Gly Val Tyr Val Ala Ala Val Arg Glu Phe 
                165                 170                 175     


Tyr Leu Ser Val Tyr Phe Phe Lys Lys Lys Thr Thr Ser Arg Phe Thr 
            180                 185                 190         


Leu Ser Ser Ser Arg Asn Lys Lys His Ala Lys Asn Asn Phe Thr Cys 
        195                 200                 205             


Val Ala Cys His Pro Thr Glu Asp Cys Ile Ala Ser Gly His Met Asp 
    210                 215                 220                 


Gly Lys Ile Arg Leu Trp Arg Asn Phe Tyr Asp Asp Lys Lys Tyr Thr 
225                 230                 235                 240 


Tyr Thr Cys Leu His Trp His His Asp Met Val Met Asp Leu Ala Phe 
                245                 250                 255     


Ser Val Thr Gly Thr Ser Leu Leu Ser Gly Gly Arg Glu Ser Val Leu 
            260                 265                 270         


Val Glu Trp Arg Asp Ala Thr Glu Lys Asn Lys Glu Phe Leu Pro Arg 
        275                 280                 285             


Leu Gly Ala Thr Ile Glu His Ile Ser Val Ser Pro Ala Gly Asp Leu 
    290                 295                 300                 


Phe Cys Thr Ser His Ser Asp Asn Lys Ile Ile Ile Ile His Arg Asn 
305                 310                 315                 320 


Leu Glu Ala Ser Ala Val Ile Gln Gly Leu Val Lys Asp Arg Ser Ile 
                325                 330                 335     


Phe Thr Gly Leu Met Ile Asp Pro Arg Thr Lys Ala Leu Val Leu Asn 
            340                 345                 350         


Gly Lys Pro Gly His Leu Gln Phe Tyr Ser Leu Gln Ser Asp Lys Gln 
        355                 360                 365             


Leu Tyr Asn Leu Asp Ile Ile Gln Gln Glu Tyr Ile Asn Asp Tyr Gly 
    370                 375                 380                 


Leu Ile Gln Ile Glu Leu Thr Lys Ala Ala Phe Gly Cys Phe Gly Asn 
385                 390                 395                 400 


Trp Leu Ala Thr Val Glu Gln Arg Gln Glu Lys Glu Thr Glu Leu Glu 
                405                 410                 415     


Leu Gln Met Lys Leu Trp Met Tyr Asn Lys Lys Thr Gln Gly Phe Ile 
            420                 425                 430         


Leu Asn Thr Lys Ile Asn Met Pro His Glu Asp Cys Ile Thr Ala Leu 
        435                 440                 445             


Cys Phe Cys Asn Ala Glu Lys Ser Glu Gln Pro Thr Leu Val Thr Ala 
    450                 455                 460                 


Ser Lys Asp Gly Tyr Phe Lys Val Trp Ile Leu Thr Asp Asp Ser Asp 
465                 470                 475                 480 


Ile Tyr Lys Lys Ala Val Gly Trp Thr Cys Asp Phe Val Gly Ser Tyr 
                485                 490                 495     


His Lys Tyr Gln Ala Thr Asn Cys Cys Phe Ser Glu Asp Gly Ser Leu 
            500                 505                 510         


Leu Ala Val Ser Phe Glu Glu Ile Val Thr Ile Trp Asp Ser Val Thr 
        515                 520                 525             


Trp Glu Leu Lys Cys Thr Phe Cys Gln Arg Ala Gly Lys Ile Arg His 
    530                 535                 540                 


Leu Cys Phe Gly Arg Leu Thr Cys Ser Lys Tyr Leu Leu Gly Ala Thr 
545                 550                 555                 560 


Glu Asn Gly Ile Leu Cys Cys Trp Asn Leu Leu Ser Cys Ala Leu Glu 
                565                 570                 575     


Trp Asn Ala Lys Leu Asn Val Arg Val Met Glu Pro Asp Pro Asn Ser 
            580                 585                 590         


Glu Asn Ile Ala Ala Ile Ser Gln Ser Ser Val Gly Ser Asp Leu Phe 
        595                 600                 605             


Val Phe Lys Pro Ser Glu Pro Arg Pro Leu Tyr Ile Gln Lys Gly Ile 
    610                 615                 620                 


Ser Arg Glu Lys Val Gln Trp Gly Val Phe Val Pro Arg Asp Val Pro 
625                 630                 635                 640 


Glu Ser Phe Thr Ser Glu Ala Tyr Gln Trp Leu Asn Arg Ser Gln Phe 
                645                 650                 655     


Tyr Phe Leu Thr Lys Ser Gln Ser Leu Leu Thr Phe Ser Thr Lys Ser 
            660                 665                 670         


Pro Glu Glu Lys Leu Thr Pro Thr Ser Lys Gln Leu Leu Ala Glu Glu 
        675                 680                 685             


Ser Leu Pro Thr Thr Pro Phe Tyr Phe Ile Leu Gly Lys His Arg Gln 
    690                 695                 700                 


Gln Gln Asp Glu Lys Leu Asn Glu Thr Leu Glu Asn Glu Leu Val Gln 
705                 710                 715                 720 


Leu Pro Leu Thr Glu Asn Ile Pro Ala Ile Ser Glu Leu Leu His Thr 
                725                 730                 735     


Pro Ala His Val Leu Pro Ser Ala Ala Phe Leu Cys Ser Met Phe Val 
            740                 745                 750         


Asn Ser Leu Leu Leu Ser Lys Glu Thr Lys Ser Ala Lys Glu Ile Pro 
        755                 760                 765             


Glu Asp Val Asp Met Glu Glu Glu Lys Glu Ser Glu Asp Ser Asp Glu 
    770                 775                 780                 


Glu Asn Asp Phe Thr Glu Lys Val Gln Asp Thr Ser Asn Thr Gly Leu 
785                 790                 795                 800 


Gly Glu Asp Ile Ile His Gln Leu Ser Lys Ser Glu Glu Lys Glu Leu 
                805                 810                 815     


Arg Lys Phe Arg Lys Ile Asp Tyr Ser Trp Ile Ala Ala Leu 
            820                 825                 830 


<210>  3959
<211>  848
<212>  PRT
<213>  homo sapiens

<400>  3959

Met Trp Leu Arg Leu Gly Pro Pro Ser Leu Ser Leu Ser Pro Lys Pro 
1               5                   10                  15      


Thr Val Gly Arg Ser Leu Cys Leu Thr Leu Trp Phe Leu Ser Leu Ala 
            20                  25                  30          


Leu Arg Ala Ser Thr Gln Ala Pro Ala Pro Thr Val Asn Thr His Phe 
        35                  40                  45              


Gly Lys Leu Arg Gly Ala Arg Val Pro Leu Pro Ser Glu Ile Leu Gly 
    50                  55                  60                  


Pro Val Asp Gln Tyr Leu Gly Val Pro Tyr Ala Ala Pro Pro Ile Gly 
65                  70                  75                  80  


Glu Lys Arg Phe Leu Pro Pro Glu Pro Pro Pro Ser Trp Ser Gly Ile 
                85                  90                  95      


Arg Asn Ala Thr His Phe Pro Pro Val Cys Pro Gln Asn Ile His Thr 
            100                 105                 110         


Ala Val Pro Glu Val Met Leu Pro Val Trp Phe Thr Ala Asn Leu Asp 
        115                 120                 125             


Ile Val Ala Thr Tyr Ile Gln Glu Pro Asn Glu Asp Cys Leu Tyr Leu 
    130                 135                 140                 


Asn Val Tyr Val Pro Thr Glu Asp Val Lys Arg Ile Ser Lys Glu Cys 
145                 150                 155                 160 


Ala Arg Lys Pro Asn Lys Lys Ile Cys Arg Lys Gly Gly Ser Gly Ala 
                165                 170                 175     


Lys Lys Gln Gly Glu Asp Leu Ala Asp Asn Asp Gly Asp Glu Asp Glu 
            180                 185                 190         


Asp Ile Arg Asp Ser Gly Ala Lys Pro Val Met Val Tyr Ile His Gly 
        195                 200                 205             


Gly Ser Tyr Met Glu Gly Thr Gly Asn Met Ile Asp Gly Ser Ile Leu 
    210                 215                 220                 


Ala Ser Tyr Gly Asn Val Ile Val Ile Thr Leu Asn Tyr Arg Val Gly 
225                 230                 235                 240 


Val Leu Gly Phe Leu Ser Thr Gly Asp Gln Ala Ala Lys Gly Asn Tyr 
                245                 250                 255     


Gly Leu Leu Asp Gln Ile Gln Ala Leu Arg Trp Val Ser Glu Asn Ile 
            260                 265                 270         


Ala Phe Phe Gly Gly Asp Pro Arg Arg Ile Thr Val Phe Gly Ser Gly 
        275                 280                 285             


Ile Gly Ala Ser Cys Val Ser Leu Leu Thr Leu Ser His His Ser Glu 
    290                 295                 300                 


Gly Leu Phe Gln Arg Ala Ile Ile Gln Ser Gly Ser Ala Leu Ser Ser 
305                 310                 315                 320 


Trp Ala Val Asn Tyr Gln Pro Val Lys Tyr Thr Ser Leu Leu Ala Asp 
                325                 330                 335     


Lys Val Gly Cys Asn Val Leu Asp Thr Val Asp Met Val Asp Cys Leu 
            340                 345                 350         


Arg Gln Lys Ser Ala Lys Glu Leu Val Glu Gln Asp Ile Gln Pro Ala 
        355                 360                 365             


Arg Tyr His Val Ala Phe Gly Pro Val Ile Asp Gly Asp Val Ile Pro 
    370                 375                 380                 


Asp Asp Pro Glu Ile Leu Met Glu Gln Gly Glu Phe Leu Asn Tyr Asp 
385                 390                 395                 400 


Ile Met Leu Gly Val Asn Gln Gly Glu Gly Leu Lys Phe Val Glu Gly 
                405                 410                 415     


Val Val Asp Pro Glu Asp Gly Val Ser Gly Thr Asp Phe Asp Tyr Ser 
            420                 425                 430         


Val Ser Asn Phe Val Asp Asn Leu Tyr Gly Tyr Pro Glu Gly Lys Asp 
        435                 440                 445             


Thr Leu Arg Glu Thr Ile Lys Phe Met Tyr Thr Asp Trp Ala Asp Arg 
    450                 455                 460                 


Asp Asn Pro Glu Thr Arg Arg Lys Thr Leu Val Ala Leu Phe Thr Asp 
465                 470                 475                 480 


His Gln Trp Val Glu Pro Ser Val Val Thr Ala Asp Leu His Ala Arg 
                485                 490                 495     


Tyr Gly Ser Pro Thr Tyr Phe Tyr Ala Phe Tyr His His Cys Gln Ser 
            500                 505                 510         


Leu Met Lys Pro Ala Trp Ser Asp Ala Ala His Gly Asp Glu Val Pro 
        515                 520                 525             


Tyr Val Phe Gly Val Pro Met Val Gly Pro Thr Asp Leu Phe Pro Cys 
    530                 535                 540                 


Asn Phe Ser Lys Asn Asp Val Met Leu Ser Ala Val Val Met Thr Tyr 
545                 550                 555                 560 


Trp Thr Asn Phe Ala Lys Thr Gly Asp Pro Asn Lys Pro Val Pro Gln 
                565                 570                 575     


Asp Thr Lys Phe Ile His Thr Lys Ala Asn Arg Phe Glu Glu Val Ala 
            580                 585                 590         


Trp Ser Lys Tyr Asn Pro Arg Asp Gln Leu Tyr Leu His Ile Gly Leu 
        595                 600                 605             


Lys Pro Arg Val Arg Asp His Tyr Arg Ala Thr Lys Val Ala Phe Trp 
    610                 615                 620                 


Lys His Leu Val Pro His Leu Tyr Asn Leu His Asp Met Phe His Tyr 
625                 630                 635                 640 


Thr Ser Thr Thr Thr Lys Val Pro Pro Pro Asp Thr Thr His Ser Ser 
                645                 650                 655     


His Ile Thr Arg Arg Pro Asn Gly Lys Thr Trp Ser Thr Lys Arg Pro 
            660                 665                 670         


Ala Ile Ser Pro Ala Tyr Ser Asn Glu Asn Ala Gln Gly Ser Trp Asn 
        675                 680                 685             


Gly Asp Gln Asp Ala Gly Pro Leu Leu Val Glu Asn Pro Arg Asp Tyr 
    690                 695                 700                 


Ser Thr Glu Leu Ser Val Thr Ile Ala Val Gly Ala Ser Leu Leu Phe 
705                 710                 715                 720 


Leu Asn Val Leu Ala Phe Ala Ala Leu Tyr Tyr Arg Lys Asp Lys Arg 
                725                 730                 735     


Arg Gln Glu Pro Leu Arg Gln Pro Ser Pro Gln Arg Gly Ala Gly Ala 
            740                 745                 750         


Pro Glu Leu Gly Ala Ala Pro Glu Glu Glu Leu Ala Ala Leu Gln Leu 
        755                 760                 765             


Gly Pro Thr His His Glu Cys Glu Ala Gly Pro Pro His Asp Thr Leu 
    770                 775                 780                 


Arg Leu Thr Ala Leu Pro Asp Tyr Thr Leu Thr Leu Arg Arg Ser Pro 
785                 790                 795                 800 


Asp Asp Ile Pro Leu Met Thr Pro Asn Thr Ile Thr Met Ile Pro Asn 
                805                 810                 815     


Ser Leu Val Gly Leu Gln Thr Leu His Pro Tyr Asn Thr Phe Ala Ala 
            820                 825                 830         


Gly Phe Asn Ser Thr Gly Leu Pro His Ser His Ser Thr Thr Arg Val 
        835                 840                 845             


<210>  3960
<211>  144
<212>  PRT
<213>  homo sapiens

<400>  3960

Met Tyr Ser Glu Ile Gln Arg Glu Arg Ala Asp Ile Gly Gly Leu Met 
1               5                   10                  15      


Ala Arg Pro Glu Tyr Arg Glu Trp Asn Pro Glu Leu Ile Lys Pro Lys 
            20                  25                  30          


Lys Leu Leu Asn Pro Val Lys Ala Ser Arg Ser His Gln Glu Leu His 
        35                  40                  45              


Arg Glu Leu Leu Met Asn His Arg Arg Gly Leu Gly Val Asp Ser Lys 
    50                  55                  60                  


Pro Glu Leu Gln Arg Val Leu Glu His Arg Arg Arg Asn Gln Leu Ile 
65                  70                  75                  80  


Lys Lys Lys Lys Glu Glu Leu Glu Ala Lys Arg Leu Gln Cys Pro Phe 
                85                  90                  95      


Glu Gln Glu Leu Leu Arg Arg Gln Gln Arg Leu Asn Gln Leu Glu Lys 
            100                 105                 110         


Pro Pro Glu Lys Glu Glu Asp His Ala Pro Glu Phe Ile Lys Val Arg 
        115                 120                 125             


Glu Asn Leu Arg Arg Ile Ala Thr Leu Thr Ser Glu Glu Arg Glu Leu 
    130                 135                 140                 


<210>  3961
<211>  304
<212>  PRT
<213>  homo sapiens

<400>  3961

Met Gly Val Phe Cys Leu Gly Pro Trp Gly Leu Gly Arg Lys Leu Arg 
1               5                   10                  15      


Thr Pro Gly Lys Gly Pro Leu Gln Leu Leu Ser Arg Leu Cys Gly Asp 
            20                  25                  30          


His Leu Gln Ala Ile Pro Ala Lys Lys Ala Pro Ala Gly Gln Glu Glu 
        35                  40                  45              


Pro Gly Thr Pro Pro Ser Ser Pro Leu Ser Ala Glu Gln Leu Asp Arg 
    50                  55                  60                  


Ile Gln Arg Asn Lys Ala Ala Ala Leu Leu Arg Leu Ala Ala Arg Asn 
65                  70                  75                  80  


Val Pro Val Gly Phe Gly Glu Ser Trp Lys Lys His Leu Ser Gly Glu 
                85                  90                  95      


Phe Gly Lys Pro Tyr Phe Ile Lys Leu Met Gly Phe Val Ala Glu Glu 
            100                 105                 110         


Arg Lys His Tyr Thr Val Tyr Pro Pro Pro His Gln Val Phe Thr Trp 
        115                 120                 125             


Thr Gln Met Cys Asp Ile Lys Asp Val Lys Val Val Ile Leu Gly Gln 
    130                 135                 140                 


Asp Pro Tyr His Gly Pro Asn Gln Ala His Gly Leu Cys Phe Ser Val 
145                 150                 155                 160 


Gln Arg Pro Val Pro Pro Pro Pro Ser Leu Glu Asn Ile Tyr Lys Glu 
                165                 170                 175     


Leu Ser Thr Asp Ile Glu Asp Phe Val His Pro Gly His Gly Asp Leu 
            180                 185                 190         


Ser Gly Trp Ala Lys Gln Gly Val Leu Leu Leu Asn Ala Val Leu Thr 
        195                 200                 205             


Val Arg Ala His Gln Ala Asn Ser His Lys Glu Arg Gly Trp Glu Gln 
    210                 215                 220                 


Phe Thr Asp Ala Val Val Ser Trp Leu Asn Gln Asn Ser Asn Gly Leu 
225                 230                 235                 240 


Val Phe Leu Leu Trp Gly Ser Tyr Ala Gln Lys Lys Gly Ser Ala Ile 
                245                 250                 255     


Asp Arg Lys Arg His His Val Leu Gln Thr Ala His Pro Ser Pro Leu 
            260                 265                 270         


Ser Val Tyr Arg Gly Phe Phe Gly Cys Arg His Phe Ser Lys Thr Asn 
        275                 280                 285             


Glu Leu Leu Gln Lys Ser Gly Lys Lys Pro Ile Asp Trp Lys Glu Leu 
    290                 295                 300                 


<210>  3962
<211>  2315
<212>  PRT
<213>  homo sapiens

<400>  3962

Met Arg Ile Leu Lys Arg Phe Leu Ala Cys Ile Gln Leu Leu Cys Val 
1               5                   10                  15      


Cys Arg Leu Asp Trp Ala Asn Gly Tyr Tyr Arg Gln Gln Arg Lys Leu 
            20                  25                  30          


Val Glu Glu Ile Gly Trp Ser Tyr Thr Gly Ala Leu Asn Gln Lys Asn 
        35                  40                  45              


Trp Gly Lys Lys Tyr Pro Thr Cys Asn Ser Pro Lys Gln Ser Pro Ile 
    50                  55                  60                  


Asn Ile Asp Glu Asp Leu Thr Gln Val Asn Val Asn Leu Lys Lys Leu 
65                  70                  75                  80  


Lys Phe Gln Gly Trp Asp Lys Thr Ser Leu Glu Asn Thr Phe Ile His 
                85                  90                  95      


Asn Thr Gly Lys Thr Val Glu Ile Asn Leu Thr Asn Asp Tyr Arg Val 
            100                 105                 110         


Ser Gly Gly Val Ser Glu Met Val Phe Lys Ala Ser Lys Ile Thr Phe 
        115                 120                 125             


His Trp Gly Lys Cys Asn Met Ser Ser Asp Gly Ser Glu His Ser Leu 
    130                 135                 140                 


Glu Gly Gln Lys Phe Pro Leu Glu Met Gln Ile Tyr Cys Phe Asp Ala 
145                 150                 155                 160 


Asp Arg Phe Ser Ser Phe Glu Glu Ala Val Lys Gly Lys Gly Lys Leu 
                165                 170                 175     


Arg Ala Leu Ser Ile Leu Phe Glu Val Gly Thr Glu Glu Asn Leu Asp 
            180                 185                 190         


Phe Lys Ala Ile Ile Asp Gly Val Glu Ser Val Ser Arg Phe Gly Lys 
        195                 200                 205             


Gln Ala Ala Leu Asp Pro Phe Ile Leu Leu Asn Leu Leu Pro Asn Ser 
    210                 215                 220                 


Thr Asp Lys Tyr Tyr Ile Tyr Asn Gly Ser Leu Thr Ser Pro Pro Cys 
225                 230                 235                 240 


Thr Asp Thr Val Asp Trp Ile Val Phe Lys Asp Thr Val Ser Ile Ser 
                245                 250                 255     


Glu Ser Gln Leu Ala Val Phe Cys Glu Val Leu Thr Met Gln Gln Ser 
            260                 265                 270         


Gly Tyr Val Met Leu Met Asp Tyr Leu Gln Asn Asn Phe Arg Glu Gln 
        275                 280                 285             


Gln Tyr Lys Phe Ser Arg Gln Val Phe Ser Ser Tyr Thr Gly Lys Glu 
    290                 295                 300                 


Glu Ile His Glu Ala Val Cys Ser Ser Glu Pro Glu Asn Val Gln Ala 
305                 310                 315                 320 


Asp Pro Glu Asn Tyr Thr Ser Leu Leu Val Thr Trp Glu Arg Pro Arg 
                325                 330                 335     


Val Val Tyr Asp Thr Met Ile Glu Lys Phe Ala Val Leu Tyr Gln Gln 
            340                 345                 350         


Leu Asp Gly Glu Asp Gln Thr Lys His Glu Phe Leu Thr Asp Gly Tyr 
        355                 360                 365             


Gln Asp Leu Gly Ala Ile Leu Asn Asn Leu Leu Pro Asn Met Ser Tyr 
    370                 375                 380                 


Val Leu Gln Ile Val Ala Ile Cys Thr Asn Gly Leu Tyr Gly Lys Tyr 
385                 390                 395                 400 


Ser Asp Gln Leu Ile Val Asp Met Pro Thr Asp Asn Pro Glu Leu Asp 
                405                 410                 415     


Leu Phe Pro Glu Leu Ile Gly Thr Glu Glu Ile Ile Lys Glu Glu Glu 
            420                 425                 430         


Glu Gly Lys Asp Ile Glu Glu Gly Ala Ile Val Asn Pro Gly Arg Asp 
        435                 440                 445             


Ser Ala Thr Asn Gln Ile Arg Lys Lys Glu Pro Gln Ile Ser Thr Thr 
    450                 455                 460                 


Thr His Tyr Asn Arg Ile Gly Thr Lys Tyr Asn Glu Ala Lys Thr Asn 
465                 470                 475                 480 


Arg Ser Pro Thr Arg Gly Ser Glu Phe Ser Gly Lys Gly Asp Val Pro 
                485                 490                 495     


Asn Thr Ser Leu Asn Ser Thr Ser Gln Pro Val Thr Lys Leu Ala Thr 
            500                 505                 510         


Glu Lys Asp Ile Ser Leu Thr Ser Gln Thr Val Thr Glu Leu Pro Pro 
        515                 520                 525             


His Thr Val Glu Gly Thr Ser Ala Ser Leu Asn Asp Gly Ser Lys Thr 
    530                 535                 540                 


Val Leu Arg Ser Pro His Met Asn Leu Ser Gly Thr Ala Glu Ser Leu 
545                 550                 555                 560 


Asn Thr Val Ser Ile Thr Glu Tyr Glu Glu Glu Ser Leu Leu Thr Ser 
                565                 570                 575     


Phe Lys Leu Asp Thr Gly Ala Glu Asp Ser Ser Gly Ser Ser Pro Ala 
            580                 585                 590         


Thr Ser Ala Ile Pro Phe Ile Ser Glu Asn Ile Ser Gln Gly Tyr Ile 
        595                 600                 605             


Phe Ser Ser Glu Asn Pro Glu Thr Ile Thr Tyr Asp Val Leu Ile Pro 
    610                 615                 620                 


Glu Ser Ala Arg Asn Ala Ser Glu Asp Ser Thr Ser Ser Gly Ser Glu 
625                 630                 635                 640 


Glu Ser Leu Lys Asp Pro Ser Met Glu Gly Asn Val Trp Phe Pro Ser 
                645                 650                 655     


Ser Thr Asp Ile Thr Ala Gln Pro Asp Val Gly Ser Gly Arg Glu Ser 
            660                 665                 670         


Phe Leu Gln Thr Asn Tyr Thr Glu Ile Arg Val Asp Glu Ser Glu Lys 
        675                 680                 685             


Thr Thr Lys Ser Phe Ser Ala Gly Pro Val Met Ser Gln Gly Pro Ser 
    690                 695                 700                 


Val Thr Asp Leu Glu Met Pro His Tyr Ser Thr Phe Ala Tyr Phe Pro 
705                 710                 715                 720 


Thr Glu Val Thr Pro His Ala Phe Thr Pro Ser Ser Arg Gln Gln Asp 
                725                 730                 735     


Leu Val Ser Thr Val Asn Val Val Tyr Ser Gln Thr Thr Gln Pro Val 
            740                 745                 750         


Tyr Asn Gly Glu Thr Pro Leu Gln Pro Ser Tyr Ser Ser Glu Val Phe 
        755                 760                 765             


Pro Leu Val Thr Pro Leu Leu Leu Asp Asn Gln Ile Leu Asn Thr Thr 
    770                 775                 780                 


Pro Ala Ala Ser Ser Ser Asp Ser Ala Leu His Ala Thr Pro Val Phe 
785                 790                 795                 800 


Pro Ser Val Asp Val Ser Phe Glu Ser Ile Leu Ser Ser Tyr Asp Gly 
                805                 810                 815     


Ala Pro Leu Leu Pro Phe Ser Ser Ala Ser Phe Ser Ser Glu Leu Phe 
            820                 825                 830         


Arg His Leu His Thr Val Ser Gln Ile Leu Pro Gln Val Thr Ser Ala 
        835                 840                 845             


Thr Glu Ser Asp Lys Val Pro Leu His Ala Ser Leu Pro Val Ala Gly 
    850                 855                 860                 


Gly Asp Leu Leu Leu Glu Pro Ser Leu Ala Gln Tyr Ser Asp Val Leu 
865                 870                 875                 880 


Ser Thr Thr His Ala Ala Ser Glu Thr Leu Glu Phe Gly Ser Glu Ser 
                885                 890                 895     


Gly Val Leu Tyr Lys Thr Leu Met Phe Ser Gln Val Glu Pro Pro Ser 
            900                 905                 910         


Ser Asp Ala Met Met His Ala Arg Ser Ser Gly Pro Glu Pro Ser Tyr 
        915                 920                 925             


Ala Leu Ser Asp Asn Glu Gly Ser Gln His Ile Phe Thr Val Ser Tyr 
    930                 935                 940                 


Ser Ser Ala Ile Pro Val His Asp Ser Val Gly Val Thr Tyr Gln Gly 
945                 950                 955                 960 


Ser Leu Phe Ser Gly Pro Ser His Ile Pro Ile Pro Lys Ser Ser Leu 
                965                 970                 975     


Ile Thr Pro Thr Ala Ser Leu Leu Gln Pro Thr His Ala Leu Ser Gly 
            980                 985                 990         


Asp Gly Glu Trp Ser Gly Ala Ser  Ser Asp Ser Glu Phe  Leu Leu Pro 
        995                 1000                 1005             


Asp Thr  Asp Gly Leu Thr Ala  Leu Asn Ile Ser Ser  Pro Val Ser 
    1010                 1015                 1020             


Val Ala  Glu Phe Thr Tyr Thr  Thr Ser Val Phe Gly  Asp Asp Asn 
    1025                 1030                 1035             


Lys Ala  Leu Ser Lys Ser Glu  Ile Ile Tyr Gly Asn  Glu Thr Glu 
    1040                 1045                 1050             


Leu Gln  Ile Pro Ser Phe Asn  Glu Met Val Tyr Pro  Ser Glu Ser 
    1055                 1060                 1065             


Thr Val  Met Pro Asn Met Tyr  Asp Asn Val Asn Lys  Leu Asn Ala 
    1070                 1075                 1080             


Ser Leu  Gln Glu Thr Ser Val  Ser Ile Ser Ser Thr  Lys Gly Met 
    1085                 1090                 1095             


Phe Pro  Gly Ser Leu Ala His  Thr Thr Thr Lys Val  Phe Asp His 
    1100                 1105                 1110             


Glu Ile  Ser Gln Val Pro Glu  Asn Asn Phe Ser Val  Gln Pro Thr 
    1115                 1120                 1125             


His Thr  Val Ser Gln Ala Ser  Gly Asp Thr Ser Leu  Lys Pro Val 
    1130                 1135                 1140             


Leu Ser  Ala Asn Ser Glu Pro  Ala Ser Ser Asp Pro  Ala Ser Ser 
    1145                 1150                 1155             


Glu Met  Leu Ser Pro Ser Thr  Gln Leu Leu Phe Tyr  Glu Thr Ser 
    1160                 1165                 1170             


Ala Ser  Phe Ser Thr Glu Val  Leu Leu Gln Pro Ser  Phe Gln Ala 
    1175                 1180                 1185             


Ser Asp  Val Asp Thr Leu Leu  Lys Thr Val Leu Pro  Ala Val Pro 
    1190                 1195                 1200             


Ser Asp  Pro Ile Leu Val Glu  Thr Pro Lys Val Asp  Lys Ile Ser 
    1205                 1210                 1215             


Ser Thr  Met Leu His Leu Ile  Val Ser Asn Ser Ala  Ser Ser Glu 
    1220                 1225                 1230             


Asn Met  Leu His Ser Thr Ser  Val Pro Val Phe Asp  Val Ser Pro 
    1235                 1240                 1245             


Thr Ser  His Met His Ser Ala  Ser Leu Gln Gly Leu  Thr Ile Ser 
    1250                 1255                 1260             


Tyr Ala  Ser Glu Lys Tyr Glu  Pro Val Leu Leu Lys  Ser Glu Ser 
    1265                 1270                 1275             


Ser His  Gln Val Val Pro Ser  Leu Tyr Ser Asn Asp  Glu Leu Phe 
    1280                 1285                 1290             


Gln Thr  Ala Asn Leu Glu Ile  Asn Gln Ala His Pro  Pro Lys Gly 
    1295                 1300                 1305             


Arg His  Val Phe Ala Thr Pro  Val Leu Ser Ile Asp  Glu Pro Leu 
    1310                 1315                 1320             


Asn Thr  Leu Ile Asn Lys Leu  Ile His Ser Asp Glu  Ile Leu Thr 
    1325                 1330                 1335             


Ser Thr  Lys Ser Ser Val Thr  Gly Lys Val Phe Ala  Gly Ile Pro 
    1340                 1345                 1350             


Thr Val  Ala Ser Asp Thr Phe  Val Ser Thr Asp His  Ser Val Pro 
    1355                 1360                 1365             


Ile Gly  Asn Gly His Val Ala  Ile Thr Ala Val Ser  Pro His Arg 
    1370                 1375                 1380             


Asp Gly  Ser Val Thr Ser Thr  Lys Leu Leu Phe Pro  Ser Lys Ala 
    1385                 1390                 1395             


Thr Ser  Glu Leu Ser His Ser  Ala Lys Ser Asp Ala  Gly Leu Val 
    1400                 1405                 1410             


Gly Gly  Gly Glu Asp Gly Asp  Thr Asp Asp Asp Gly  Asp Asp Asp 
    1415                 1420                 1425             


Asp Asp  Asp Arg Gly Ser Asp  Gly Leu Ser Ile His  Lys Cys Met 
    1430                 1435                 1440             


Ser Cys  Ser Ser Tyr Arg Glu  Ser Gln Glu Lys Val  Met Asn Asp 
    1445                 1450                 1455             


Ser Asp  Thr His Glu Asn Ser  Leu Met Asp Gln Asn  Asn Pro Ile 
    1460                 1465                 1470             


Ser Tyr  Ser Leu Ser Glu Asn  Ser Glu Glu Asp Asn  Arg Val Thr 
    1475                 1480                 1485             


Ser Val  Ser Ser Asp Ser Gln  Thr Gly Met Asp Arg  Ser Pro Gly 
    1490                 1495                 1500             


Lys Ser  Pro Ser Ala Asn Gly  Leu Ser Gln Lys His  Asn Asp Gly 
    1505                 1510                 1515             


Lys Glu  Glu Asn Asp Ile Gln  Thr Gly Ser Ala Leu  Leu Pro Leu 
    1520                 1525                 1530             


Ser Pro  Glu Ser Lys Ala Trp  Ala Val Leu Thr Ser  Asp Glu Glu 
    1535                 1540                 1545             


Ser Gly  Ser Gly Gln Gly Thr  Ser Asp Ser Leu Asn  Glu Asn Glu 
    1550                 1555                 1560             


Thr Ser  Thr Asp Phe Ser Phe  Ala Asp Thr Asn Glu  Lys Asp Ala 
    1565                 1570                 1575             


Asp Gly  Ile Leu Ala Ala Gly  Asp Ser Glu Ile Thr  Pro Gly Phe 
    1580                 1585                 1590             


Pro Gln  Ser Pro Thr Ser Ser  Val Thr Ser Glu Asn  Ser Glu Val 
    1595                 1600                 1605             


Phe His  Val Ser Glu Ala Glu  Ala Ser Asn Ser Ser  His Glu Ser 
    1610                 1615                 1620             


Arg Ile  Gly Leu Ala Glu Gly  Leu Glu Ser Glu Lys  Lys Ala Val 
    1625                 1630                 1635             


Ile Pro  Leu Val Ile Val Ser  Ala Leu Thr Phe Ile  Cys Leu Val 
    1640                 1645                 1650             


Val Leu  Val Gly Ile Leu Ile  Tyr Trp Arg Lys Cys  Phe Gln Thr 
    1655                 1660                 1665             


Ala His  Phe Tyr Leu Glu Asp  Ser Thr Ser Pro Arg  Val Ile Ser 
    1670                 1675                 1680             


Thr Pro  Pro Thr Pro Ile Phe  Pro Ile Ser Asp Asp  Val Gly Ala 
    1685                 1690                 1695             


Ile Pro  Ile Lys His Phe Pro  Lys His Val Ala Asp  Leu His Ala 
    1700                 1705                 1710             


Ser Ser  Gly Phe Thr Glu Glu  Phe Glu Thr Leu Lys  Glu Phe Tyr 
    1715                 1720                 1725             


Gln Glu  Val Gln Ser Cys Thr  Val Asp Leu Gly Ile  Thr Ala Asp 
    1730                 1735                 1740             


Ser Ser  Asn His Pro Asp Asn  Lys His Lys Asn Arg  Tyr Ile Asn 
    1745                 1750                 1755             


Ile Val  Ala Tyr Asp His Ser  Arg Val Lys Leu Ala  Gln Leu Ala 
    1760                 1765                 1770             


Glu Lys  Asp Gly Lys Leu Thr  Asp Tyr Ile Asn Ala  Asn Tyr Val 
    1775                 1780                 1785             


Asp Gly  Tyr Asn Arg Pro Lys  Ala Tyr Ile Ala Ala  Gln Gly Pro 
    1790                 1795                 1800             


Leu Lys  Ser Thr Ala Glu Asp  Phe Trp Arg Met Ile  Trp Glu His 
    1805                 1810                 1815             


Asn Val  Glu Val Ile Val Met  Ile Thr Asn Leu Val  Glu Lys Gly 
    1820                 1825                 1830             


Arg Arg  Lys Cys Asp Gln Tyr  Trp Pro Ala Asp Gly  Ser Glu Glu 
    1835                 1840                 1845             


Tyr Gly  Asn Phe Leu Val Thr  Gln Lys Ser Val Gln  Val Leu Ala 
    1850                 1855                 1860             


Tyr Tyr  Thr Val Arg Asn Phe  Thr Leu Arg Asn Thr  Lys Ile Lys 
    1865                 1870                 1875             


Lys Gly  Ser Gln Lys Gly Arg  Pro Ser Gly Arg Val  Val Thr Gln 
    1880                 1885                 1890             


Tyr His  Tyr Thr Gln Trp Pro  Asp Met Gly Val Pro  Glu Tyr Ser 
    1895                 1900                 1905             


Leu Pro  Val Leu Thr Phe Val  Arg Lys Ala Ala Tyr  Ala Lys Arg 
    1910                 1915                 1920             


His Ala  Val Gly Pro Val Val  Val His Cys Ser Ala  Gly Val Gly 
    1925                 1930                 1935             


Arg Thr  Gly Thr Tyr Ile Val  Leu Asp Ser Met Leu  Gln Gln Ile 
    1940                 1945                 1950             


Gln His  Glu Gly Thr Val Asn  Ile Phe Gly Phe Leu  Lys His Ile 
    1955                 1960                 1965             


Arg Ser  Gln Arg Asn Tyr Leu  Val Gln Thr Glu Glu  Gln Tyr Val 
    1970                 1975                 1980             


Phe Ile  His Asp Thr Leu Val  Glu Ala Ile Leu Ser  Lys Glu Thr 
    1985                 1990                 1995             


Glu Val  Leu Asp Ser His Ile  His Ala Tyr Val Asn  Ala Leu Leu 
    2000                 2005                 2010             


Ile Pro  Gly Pro Ala Gly Lys  Thr Lys Leu Glu Lys  Gln Phe Gln 
    2015                 2020                 2025             


Leu Leu  Ser Gln Ser Asn Ile  Gln Gln Ser Asp Tyr  Ser Ala Ala 
    2030                 2035                 2040             


Leu Lys  Gln Cys Asn Arg Glu  Lys Asn Arg Thr Ser  Ser Ile Ile 
    2045                 2050                 2055             


Pro Val  Glu Arg Ser Arg Val  Gly Ile Ser Ser Leu  Ser Gly Glu 
    2060                 2065                 2070             


Gly Thr  Asp Tyr Ile Asn Ala  Ser Tyr Ile Met Gly  Tyr Tyr Gln 
    2075                 2080                 2085             


Ser Asn  Glu Phe Ile Ile Thr  Gln His Pro Leu Leu  His Thr Ile 
    2090                 2095                 2100             


Lys Asp  Phe Trp Arg Met Ile  Trp Asp His Asn Ala  Gln Leu Val 
    2105                 2110                 2115             


Val Met  Ile Pro Asp Gly Gln  Asn Met Ala Glu Asp  Glu Phe Val 
    2120                 2125                 2130             


Tyr Trp  Pro Asn Lys Asp Glu  Pro Ile Asn Cys Glu  Ser Phe Lys 
    2135                 2140                 2145             


Val Thr  Leu Met Ala Glu Glu  His Lys Cys Leu Ser  Asn Glu Glu 
    2150                 2155                 2160             


Lys Leu  Ile Ile Gln Asp Phe  Ile Leu Glu Ala Thr  Gln Asp Asp 
    2165                 2170                 2175             


Tyr Val  Leu Glu Val Arg His  Phe Gln Cys Pro Lys  Trp Pro Asn 
    2180                 2185                 2190             


Pro Asp  Ser Pro Ile Ser Lys  Thr Phe Glu Leu Ile  Ser Val Ile 
    2195                 2200                 2205             


Lys Glu  Glu Ala Ala Asn Arg  Asp Gly Pro Met Ile  Val His Asp 
    2210                 2215                 2220             


Glu His  Gly Gly Val Thr Ala  Gly Thr Phe Cys Ala  Leu Thr Thr 
    2225                 2230                 2235             


Leu Met  His Gln Leu Glu Lys  Glu Asn Ser Val Asp  Val Tyr Gln 
    2240                 2245                 2250             


Val Ala  Lys Met Ile Asn Leu  Met Arg Pro Gly Val  Phe Ala Asp 
    2255                 2260                 2265             


Ile Glu  Gln Tyr Gln Phe Leu  Tyr Lys Val Ile Leu  Ser Leu Val 
    2270                 2275                 2280             


Ser Thr  Arg Gln Glu Glu Asn  Pro Ser Thr Ser Leu  Asp Ser Asn 
    2285                 2290                 2295             


Gly Ala  Ala Leu Pro Asp Gly  Asn Ile Ala Glu Ser  Leu Glu Ser 
    2300                 2305                 2310             


Leu Val  
    2315 


<210>  3963
<211>  381
<212>  PRT
<213>  homo sapiens

<400>  3963

Met His Leu Leu Ala Ile Leu Phe Cys Ala Leu Trp Ser Ala Val Leu 
1               5                   10                  15      


Ala Glu Asn Ser Asp Asp Tyr Asp Leu Met Tyr Val Asn Leu Asp Asn 
            20                  25                  30          


Glu Ile Asp Asn Gly Leu His Pro Thr Glu Asp Pro Thr Pro Cys Ala 
        35                  40                  45              


Cys Gly Gln Glu His Ser Glu Trp Asp Lys Leu Phe Ile Met Leu Glu 
    50                  55                  60                  


Asn Ser Gln Met Arg Glu Arg Met Leu Leu Gln Ala Thr Asp Asp Val 
65                  70                  75                  80  


Leu Arg Gly Glu Leu Gln Arg Leu Arg Glu Glu Leu Gly Arg Leu Ala 
                85                  90                  95      


Glu Ser Leu Ala Arg Pro Cys Ala Pro Gly Ala Pro Ala Glu Ala Arg 
            100                 105                 110         


Leu Thr Ser Ala Leu Asp Glu Leu Leu Gln Ala Thr Arg Asp Ala Gly 
        115                 120                 125             


Arg Arg Leu Ala Arg Met Glu Gly Ala Glu Ala Gln Arg Pro Glu Glu 
    130                 135                 140                 


Ala Gly Arg Ala Leu Ala Ala Val Leu Glu Glu Leu Arg Gln Thr Arg 
145                 150                 155                 160 


Ala Asp Leu His Ala Val Gln Gly Trp Ala Ala Arg Ser Trp Leu Pro 
                165                 170                 175     


Ala Gly Cys Glu Thr Ala Ile Leu Phe Pro Met Arg Ser Lys Lys Ile 
            180                 185                 190         


Phe Gly Ser Val His Pro Val Arg Pro Met Arg Leu Glu Ser Phe Ser 
        195                 200                 205             


Ala Cys Ile Trp Val Lys Ala Thr Asp Val Leu Asn Lys Thr Ile Leu 
    210                 215                 220                 


Phe Ser Tyr Gly Thr Lys Arg Asn Pro Tyr Glu Ile Gln Leu Tyr Leu 
225                 230                 235                 240 


Ser Tyr Gln Ser Ile Val Phe Val Val Gly Gly Glu Glu Asn Lys Leu 
                245                 250                 255     


Val Ala Glu Ala Met Val Ser Leu Gly Arg Trp Thr His Leu Cys Gly 
            260                 265                 270         


Thr Trp Asn Ser Glu Glu Gly Leu Thr Ser Leu Trp Val Asn Gly Glu 
        275                 280                 285             


Leu Ala Ala Thr Thr Val Glu Met Ala Thr Gly His Ile Val Pro Glu 
    290                 295                 300                 


Gly Gly Ile Leu Gln Ile Gly Gln Glu Lys Asn Gly Cys Cys Val Gly 
305                 310                 315                 320 


Gly Gly Phe Asp Glu Thr Leu Ala Phe Ser Gly Arg Leu Thr Gly Phe 
                325                 330                 335     


Asn Ile Trp Asp Ser Val Leu Ser Asn Glu Glu Ile Arg Glu Thr Gly 
            340                 345                 350         


Gly Ala Glu Ser Cys His Ile Arg Gly Asn Ile Val Gly Trp Gly Val 
        355                 360                 365             


Thr Glu Ile Gln Pro His Gly Gly Ala Gln Tyr Val Ser 
    370                 375                 380     


<210>  3964
<211>  549
<212>  PRT
<213>  homo sapiens

<400>  3964

Met Ala Arg Thr Leu Arg Pro Ser Pro Leu Cys Pro Gly Gly Gly Lys 
1               5                   10                  15      


Ala Gln Leu Ser Ser Ala Ser Leu Leu Gly Ala Gly Leu Leu Leu Gln 
            20                  25                  30          


Pro Pro Thr Pro Pro Pro Leu Leu Leu Leu Leu Phe Pro Leu Leu Leu 
        35                  40                  45              


Phe Ser Arg Leu Cys Gly Ala Leu Ala Gly Pro Ile Ile Val Glu Pro 
    50                  55                  60                  


His Val Thr Ala Val Trp Gly Lys Asn Val Ser Leu Lys Cys Leu Ile 
65                  70                  75                  80  


Glu Val Asn Glu Thr Ile Thr Gln Ile Ser Trp Glu Lys Ile His Gly 
                85                  90                  95      


Lys Ser Ser Gln Thr Val Ala Val His His Pro Gln Tyr Gly Phe Ser 
            100                 105                 110         


Val Gln Gly Glu Tyr Gln Gly Arg Val Leu Phe Lys Asn Tyr Ser Leu 
        115                 120                 125             


Asn Asp Ala Thr Ile Thr Leu His Asn Ile Gly Phe Ser Asp Ser Gly 
    130                 135                 140                 


Lys Tyr Ile Cys Lys Ala Val Thr Phe Pro Leu Gly Asn Ala Gln Ser 
145                 150                 155                 160 


Ser Thr Thr Val Thr Val Leu Val Glu Pro Thr Val Ser Leu Ile Lys 
                165                 170                 175     


Gly Pro Asp Ser Leu Ile Asp Gly Gly Asn Glu Thr Val Ala Ala Ile 
            180                 185                 190         


Cys Ile Ala Ala Thr Gly Lys Pro Val Ala His Ile Asp Trp Glu Gly 
        195                 200                 205             


Asp Leu Gly Glu Met Glu Ser Thr Thr Thr Ser Phe Pro Asn Glu Thr 
    210                 215                 220                 


Ala Thr Ile Ile Ser Gln Tyr Lys Leu Phe Pro Thr Arg Phe Ala Arg 
225                 230                 235                 240 


Gly Arg Arg Ile Thr Cys Val Val Lys His Pro Ala Leu Glu Lys Asp 
                245                 250                 255     


Ile Arg Tyr Ser Phe Ile Leu Asp Ile Gln Tyr Ala Pro Glu Val Ser 
            260                 265                 270         


Val Thr Gly Tyr Asp Gly Asn Trp Phe Val Gly Arg Lys Gly Val Asn 
        275                 280                 285             


Leu Lys Cys Asn Ala Asp Ala Asn Pro Pro Pro Phe Lys Ser Val Trp 
    290                 295                 300                 


Ser Arg Leu Asp Gly Gln Trp Pro Asp Gly Leu Leu Ala Ser Asp Asn 
305                 310                 315                 320 


Thr Leu His Phe Val His Pro Leu Thr Phe Asn Tyr Ser Gly Val Tyr 
                325                 330                 335     


Ile Cys Lys Val Thr Asn Ser Leu Gly Gln Arg Ser Asp Gln Lys Val 
            340                 345                 350         


Ile Tyr Ile Ser Asp Pro Pro Thr Thr Thr Thr Leu Gln Pro Thr Ile 
        355                 360                 365             


Gln Trp His Pro Ser Thr Ala Asp Ile Glu Asp Leu Ala Thr Glu Pro 
    370                 375                 380                 


Lys Lys Leu Pro Phe Pro Leu Ser Thr Leu Ala Thr Ile Lys Asp Asp 
385                 390                 395                 400 


Thr Ile Ala Thr Ile Ile Ala Ser Val Val Gly Gly Ala Leu Phe Ile 
                405                 410                 415     


Val Leu Val Ser Val Leu Ala Gly Ile Phe Cys Tyr Arg Arg Arg Arg 
            420                 425                 430         


Thr Phe Arg Gly Asp Tyr Phe Ala Lys Asn Tyr Ile Pro Pro Ser Asp 
        435                 440                 445             


Met Gln Lys Glu Ser Gln Ile Asp Val Leu Gln Gln Asp Glu Leu Asp 
    450                 455                 460                 


Ser Tyr Pro Asp Ser Val Lys Lys Glu Asn Lys Asn Pro Val Asn Asn 
465                 470                 475                 480 


Leu Ile Arg Lys Asp Tyr Leu Glu Glu Pro Glu Lys Thr Gln Trp Asn 
                485                 490                 495     


Asn Val Glu Asn Leu Asn Arg Phe Glu Arg Pro Met Asp Tyr Tyr Glu 
            500                 505                 510         


Asp Leu Lys Met Gly Met Lys Phe Val Ser Asp Glu His Tyr Asp Glu 
        515                 520                 525             


Asn Glu Asp Asp Leu Val Ser His Val Asp Gly Ser Val Ile Ser Arg 
    530                 535                 540                 


Arg Glu Trp Tyr Val 
545                 


<210>  3965
<211>  339
<212>  PRT
<213>  homo sapiens

<400>  3965

Met Asp Glu Thr Val Ala Glu Phe Ile Lys Arg Thr Ile Leu Lys Ile 
1               5                   10                  15      


Pro Met Asn Glu Leu Thr Thr Ile Leu Lys Ala Trp Asp Phe Leu Ser 
            20                  25                  30          


Glu Asn Gln Leu Gln Thr Val Asn Phe Arg Gln Arg Lys Glu Ser Val 
        35                  40                  45              


Val Gln His Leu Ile His Leu Cys Glu Glu Lys Arg Ala Ser Ile Ser 
    50                  55                  60                  


Asp Ala Ala Leu Leu Asp Ile Ile Tyr Met Gln Phe His Gln His Gln 
65                  70                  75                  80  


Lys Val Trp Glu Val Phe Gln Met Ser Lys Gly Pro Gly Glu Asp Val 
                85                  90                  95      


Asp Leu Phe Asp Met Lys Gln Phe Lys Asn Ser Phe Lys Lys Ile Leu 
            100                 105                 110         


Gln Arg Ala Leu Lys Asn Val Thr Val Ser Phe Arg Glu Thr Glu Glu 
        115                 120                 125             


Asn Ala Val Trp Ile Arg Ile Ala Trp Gly Thr Gln Tyr Thr Lys Pro 
    130                 135                 140                 


Asn Gln Tyr Lys Pro Thr Tyr Val Val Tyr Tyr Ser Gln Thr Pro Tyr 
145                 150                 155                 160 


Ala Phe Thr Ser Ser Ser Met Leu Arg Arg Asn Thr Pro Leu Leu Gly 
                165                 170                 175     


Gln Ala Leu Thr Ile Ala Ser Lys His His Gln Ile Val Lys Met Asp 
            180                 185                 190         


Leu Arg Ser Arg Tyr Leu Asp Ser Leu Lys Ala Ile Val Phe Lys Gln 
        195                 200                 205             


Tyr Asn Gln Thr Phe Glu Thr His Asn Ser Thr Thr Pro Leu Gln Glu 
    210                 215                 220                 


Arg Ser Leu Gly Leu Asp Ile Asn Met Asp Ser Arg Ile Ile His Glu 
225                 230                 235                 240 


Asn Ile Val Glu Lys Glu Arg Val Gln Arg Ile Thr Gln Glu Thr Phe 
                245                 250                 255     


Gly Asp Tyr Pro Gln Pro Gln Leu Glu Phe Ala Gln Tyr Lys Leu Glu 
            260                 265                 270         


Thr Lys Phe Lys Ser Gly Leu Asn Gly Ser Ile Leu Ala Glu Arg Glu 
        275                 280                 285             


Glu Pro Leu Arg Cys Leu Ile Lys Phe Ser Ser Pro His Leu Leu Glu 
    290                 295                 300                 


Ala Leu Lys Ser Leu Ala Pro Ala Gly Ile Ala Asp Ala Pro Leu Ser 
305                 310                 315                 320 


Pro Leu Leu Thr Cys Ile Pro Asn Lys Arg Met Asn Tyr Phe Lys Ile 
                325                 330                 335     


Arg Asp Lys 
            


<210>  3966
<211>  498
<212>  PRT
<213>  homo sapiens

<400>  3966

Met Ala Ala Ala Ala Ala Ala Ala Pro Ser Gly Gly Gly Gly Gly Gly 
1               5                   10                  15      


Glu Glu Glu Arg Leu Glu Glu Lys Ser Glu Asp Gln Asp Leu Gln Gly 
            20                  25                  30          


Leu Lys Asp Lys Pro Leu Lys Phe Lys Lys Val Lys Lys Asp Lys Lys 
        35                  40                  45              


Glu Glu Lys Glu Gly Lys His Glu Pro Val Gln Pro Ser Ala His His 
    50                  55                  60                  


Ser Ala Glu Pro Ala Glu Ala Gly Lys Ala Glu Thr Ser Glu Gly Ser 
65                  70                  75                  80  


Gly Ser Ala Pro Ala Val Pro Glu Ala Ser Ala Ser Pro Lys Gln Arg 
                85                  90                  95      


Arg Ser Ile Ile Arg Asp Arg Gly Pro Met Tyr Asp Asp Pro Thr Leu 
            100                 105                 110         


Pro Glu Gly Trp Thr Arg Lys Leu Lys Gln Arg Lys Ser Gly Arg Ser 
        115                 120                 125             


Ala Gly Lys Tyr Asp Val Tyr Leu Ile Asn Pro Gln Gly Lys Ala Phe 
    130                 135                 140                 


Arg Ser Lys Val Glu Leu Ile Ala Tyr Phe Glu Lys Val Gly Asp Thr 
145                 150                 155                 160 


Ser Leu Asp Pro Asn Asp Phe Asp Phe Thr Val Thr Gly Arg Gly Ser 
                165                 170                 175     


Pro Ser Arg Arg Glu Gln Lys Pro Pro Lys Lys Pro Lys Ser Pro Lys 
            180                 185                 190         


Ala Pro Gly Thr Gly Arg Gly Arg Gly Arg Pro Lys Gly Ser Gly Thr 
        195                 200                 205             


Thr Arg Pro Lys Ala Ala Thr Ser Glu Gly Val Gln Val Lys Arg Val 
    210                 215                 220                 


Leu Glu Lys Ser Pro Gly Lys Leu Leu Val Lys Met Pro Phe Gln Thr 
225                 230                 235                 240 


Ser Pro Gly Gly Lys Ala Glu Gly Gly Gly Ala Thr Thr Ser Thr Gln 
                245                 250                 255     


Val Met Val Ile Lys Arg Pro Gly Arg Lys Arg Lys Ala Glu Ala Asp 
            260                 265                 270         


Pro Gln Ala Ile Pro Lys Lys Arg Gly Arg Lys Pro Gly Ser Val Val 
        275                 280                 285             


Ala Ala Ala Ala Ala Glu Ala Lys Lys Lys Ala Val Lys Glu Ser Ser 
    290                 295                 300                 


Ile Arg Ser Val Gln Glu Thr Val Leu Pro Ile Lys Lys Arg Lys Thr 
305                 310                 315                 320 


Arg Glu Thr Val Ser Ile Glu Val Lys Glu Val Val Lys Pro Leu Leu 
                325                 330                 335     


Val Ser Thr Leu Gly Glu Lys Ser Gly Lys Gly Leu Lys Thr Cys Lys 
            340                 345                 350         


Ser Pro Gly Arg Lys Ser Lys Glu Ser Ser Pro Lys Gly Arg Ser Ser 
        355                 360                 365             


Ser Ala Ser Ser Pro Pro Lys Lys Glu His His His His His His His 
    370                 375                 380                 


Ser Glu Ser Pro Lys Ala Pro Val Pro Leu Leu Pro Pro Leu Pro Pro 
385                 390                 395                 400 


Pro Pro Pro Glu Pro Glu Ser Ser Glu Asp Pro Thr Ser Pro Pro Glu 
                405                 410                 415     


Pro Gln Asp Leu Ser Ser Ser Val Cys Lys Glu Glu Lys Met Pro Arg 
            420                 425                 430         


Gly Gly Ser Leu Glu Ser Asp Gly Cys Pro Lys Glu Pro Ala Lys Thr 
        435                 440                 445             


Gln Pro Ala Val Ala Thr Ala Ala Thr Ala Ala Glu Lys Tyr Lys His 
    450                 455                 460                 


Arg Gly Glu Gly Glu Arg Lys Asp Ile Val Ser Ser Ser Met Pro Arg 
465                 470                 475                 480 


Pro Asn Arg Glu Glu Pro Val Asp Ser Arg Thr Pro Val Thr Glu Arg 
                485                 490                 495     


Val Ser 
        


<210>  3967
<211>  550
<212>  PRT
<213>  homo sapiens

<400>  3967

Met Val Arg Gly Trp Glu Pro Pro Pro Gly Leu Asp Cys Ala Ile Ser 
1               5                   10                  15      


Glu Gly His Lys Ser Glu Gly Thr Met Pro Pro Asn Lys Glu Ala Ser 
            20                  25                  30          


Gly Leu Ser Ser Ser Pro Ala Gly Leu Ile Cys Leu Pro Pro Ile Ser 
        35                  40                  45              


Glu Glu Leu Gln Leu Val Trp Thr Gln Ala Ala Gln Thr Ser Glu Leu 
    50                  55                  60                  


Asp Ser Asn Glu His Leu Leu Lys Thr Phe Ser Tyr Phe Pro Tyr Pro 
65                  70                  75                  80  


Ser Leu Ala Asp Ile Ala Leu Leu Cys Leu Arg Tyr Gly Leu Gln Met 
                85                  90                  95      


Glu Lys Val Lys Thr Trp Phe Met Ala Gln Arg Leu Arg Cys Gly Ile 
            100                 105                 110         


Ser Trp Ser Ser Glu Glu Ile Glu Glu Thr Arg Ala Arg Val Val Tyr 
        115                 120                 125             


Arg Arg Asp Gln Leu His Phe Lys Ser Leu Leu Ser Phe Thr His His 
    130                 135                 140                 


Ala Gly Arg Pro Pro Glu Glu Val Pro Pro Pro Pro Val Pro Ala Pro 
145                 150                 155                 160 


Glu Gln Val Gly Ile Gly Ile Gly Pro Pro Thr Leu Ser Lys Pro Thr 
                165                 170                 175     


Gln Thr Lys Gly Leu Lys Val Glu Pro Glu Glu Pro Ser Gln Met Pro 
            180                 185                 190         


Pro Leu Pro Gln Ser His Gln Lys Leu Lys Glu Ser Leu Met Thr Pro 
        195                 200                 205             


Gly Ser Gly Ala Phe Pro Tyr Gln Ser Asp Phe Trp Gln His Leu Gln 
    210                 215                 220                 


Ser Ser Gly Leu Ser Lys Glu Gln Ala Gly Arg Gly Pro Asn Gln Ser 
225                 230                 235                 240 


His Gly Ile Gly Thr Ala Ser Trp Asn His Ser Thr Thr Val Pro Gln 
                245                 250                 255     


Pro Gln Ala Arg Asp Lys Pro Pro Pro Ile Ala Leu Ile Ala Ser Ser 
            260                 265                 270         


Cys Lys Glu Glu Ser Ala Ser Ser Val Thr Pro Ser Ser Ser Ser Thr 
        275                 280                 285             


Ser Ser Ser Phe Gln Val Leu Ala Asn Gly Ala Thr Ala Ala Ser Lys 
    290                 295                 300                 


Pro Leu Gln Pro Leu Gly Cys Val Pro Gln Ser Val Ser Pro Ser Glu 
305                 310                 315                 320 


Gln Ala Leu Pro Pro His Leu Glu Pro Ala Trp Pro Gln Gly Leu Arg 
                325                 330                 335     


His Asn Ser Val Pro Gly Arg Val Gly Pro Thr Glu Tyr Leu Ser Pro 
            340                 345                 350         


Asp Met Gln Arg Gln Arg Lys Thr Lys Arg Lys Thr Lys Glu Gln Leu 
        355                 360                 365             


Ala Ile Leu Lys Ser Phe Phe Leu Gln Cys Gln Trp Ala Arg Arg Glu 
    370                 375                 380                 


Asp Tyr Gln Lys Leu Glu Gln Ile Thr Gly Leu Pro Arg Pro Glu Ile 
385                 390                 395                 400 


Ile Gln Trp Phe Gly Asp Thr Arg Tyr Ala Leu Lys His Gly Gln Leu 
                405                 410                 415     


Lys Trp Phe Arg Asp Asn Ala Val Pro Gly Ala Pro Ser Phe Gln Asp 
            420                 425                 430         


Pro Ala Ile Pro Thr Pro Pro Pro Ser Thr Arg Ser Leu Asn Glu Arg 
        435                 440                 445             


Ala Glu Thr Pro Pro Leu Pro Ile Pro Pro Pro Pro Pro Asp Ile Gln 
    450                 455                 460                 


Pro Leu Glu Arg Tyr Trp Ala Ala His Gln Gln Leu Arg Glu Thr Asp 
465                 470                 475                 480 


Ile Pro Gln Leu Ser Gln Ala Ser Arg Leu Ser Thr Gln Gln Val Leu 
                485                 490                 495     


Asp Trp Phe Asp Ser Arg Leu Pro Gln Pro Ala Glu Val Val Val Cys 
            500                 505                 510         


Leu Asp Glu Glu Glu Glu Glu Glu Glu Glu Glu Leu Pro Glu Asp Asp 
        515                 520                 525             


Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp Asp Asp Asp Asp Asp Asp 
    530                 535                 540                 


Asp Val Ile Ile Gln Asp 
545                 550 


<210>  3968
<211>  721
<212>  PRT
<213>  homo sapiens

<400>  3968

Met Gly Asp Ala Glu Ser Cys Leu Leu Arg Gln Gln Thr Arg Glu Val 
1               5                   10                  15      


Arg Lys Lys Pro Leu Ile Asn Tyr Arg Phe Leu Arg Ala Ala Ala Asn 
            20                  25                  30          


Ala Glu Pro Arg Gly Pro Gln Ala Gln Arg Thr Ser Cys Ala Lys Arg 
        35                  40                  45              


Glu Cys Gly Ala Phe Thr Gln Arg Val Arg Glu Arg Ala Gly Arg Gln 
    50                  55                  60                  


Pro Pro Ala Gly Gly Thr Arg His Ser Arg Ala Glu Arg Gly Arg Arg 
65                  70                  75                  80  


Arg Ser His Pro Arg Ser Arg Thr Arg Thr Thr Ala Leu Leu Arg Ser 
                85                  90                  95      


Ser Gln Thr Lys Glu Met Ala Thr Lys Glu Lys Leu Gln Cys Leu Lys 
            100                 105                 110         


Asp Phe His Lys Asp Ile Leu Lys Pro Ser Pro Gly Lys Ser Pro Gly 
        115                 120                 125             


Thr Arg Pro Glu Asp Glu Ala Glu Gly Lys Pro Pro Gln Arg Glu Lys 
    130                 135                 140                 


Trp Ser Ser Lys Ile Asp Phe Val Leu Ser Val Ala Gly Gly Phe Val 
145                 150                 155                 160 


Gly Leu Gly Asn Val Trp Arg Phe Pro Tyr Leu Cys Tyr Lys Asn Gly 
                165                 170                 175     


Gly Gly Ala Phe Leu Ile Pro Tyr Phe Ile Phe Leu Phe Gly Ser Gly 
            180                 185                 190         


Leu Pro Val Phe Phe Leu Glu Ile Ile Ile Gly Gln Tyr Thr Ser Glu 
        195                 200                 205             


Gly Gly Ile Thr Cys Trp Glu Lys Ile Cys Pro Leu Phe Ser Gly Ile 
    210                 215                 220                 


Gly Tyr Ala Ser Val Val Ile Val Ser Leu Leu Asn Val Tyr Tyr Ile 
225                 230                 235                 240 


Val Ile Leu Ala Trp Ala Thr Tyr Tyr Leu Phe Gln Ser Phe Gln Lys 
                245                 250                 255     


Glu Leu Pro Trp Ala His Cys Asn His Ser Trp Asn Thr Pro His Cys 
            260                 265                 270         


Met Glu Asp Thr Met Arg Lys Asn Lys Ser Val Trp Ile Thr Ile Ser 
        275                 280                 285             


Ser Thr Asn Phe Thr Ser Pro Val Ile Glu Phe Trp Glu Arg Asn Val 
    290                 295                 300                 


Leu Ser Leu Ser Pro Gly Ile Asp His Pro Gly Ser Leu Lys Trp Asp 
305                 310                 315                 320 


Leu Ala Leu Cys Leu Leu Leu Val Trp Leu Val Cys Phe Phe Cys Ile 
                325                 330                 335     


Trp Lys Gly Val Arg Ser Thr Gly Lys Val Val Tyr Phe Thr Ala Thr 
            340                 345                 350         


Phe Pro Phe Ala Met Leu Leu Val Leu Leu Val Arg Gly Leu Thr Leu 
        355                 360                 365             


Pro Gly Ala Gly Ala Gly Ile Lys Phe Tyr Leu Tyr Pro Asp Ile Thr 
    370                 375                 380                 


Arg Leu Glu Asp Pro Gln Val Trp Ile Asp Ala Gly Thr Gln Ile Phe 
385                 390                 395                 400 


Phe Ser Tyr Ala Ile Cys Leu Gly Ala Met Thr Ser Leu Gly Ser Tyr 
                405                 410                 415     


Asn Lys Tyr Lys Tyr Asn Ser Tyr Arg Asp Cys Met Leu Leu Gly Cys 
            420                 425                 430         


Leu Asn Ser Gly Thr Ser Phe Val Ser Gly Phe Ala Ile Phe Ser Ile 
        435                 440                 445             


Leu Gly Phe Met Ala Gln Glu Gln Gly Val Asp Ile Ala Asp Val Ala 
    450                 455                 460                 


Glu Ser Gly Pro Gly Leu Ala Phe Ile Ala Tyr Pro Lys Ala Val Thr 
465                 470                 475                 480 


Met Met Pro Leu Pro Thr Phe Trp Ser Ile Leu Phe Phe Ile Met Leu 
                485                 490                 495     


Leu Leu Leu Gly Leu Asp Ser Gln Phe Val Glu Val Glu Gly Gln Ile 
            500                 505                 510         


Thr Ser Leu Val Asp Leu Tyr Pro Ser Phe Leu Arg Lys Gly Tyr Arg 
        515                 520                 525             


Arg Glu Ile Phe Ile Ala Phe Val Cys Ser Ile Ser Tyr Leu Leu Gly 
    530                 535                 540                 


Leu Thr Met Val Thr Glu Gly Gly Met Tyr Val Phe Gln Leu Phe Asp 
545                 550                 555                 560 


Tyr Tyr Ala Ala Ser Gly Val Cys Leu Leu Trp Val Ala Phe Phe Glu 
                565                 570                 575     


Cys Phe Val Ile Ala Trp Ile Tyr Gly Gly Asp Asn Leu Tyr Asp Gly 
            580                 585                 590         


Ile Glu Asp Met Ile Gly Tyr Arg Pro Gly Pro Trp Met Lys Tyr Ser 
        595                 600                 605             


Trp Ala Val Ile Thr Pro Val Leu Cys Val Gly Cys Phe Ile Phe Ser 
    610                 615                 620                 


Leu Val Lys Tyr Val Pro Leu Thr Tyr Asn Lys Thr Tyr Val Tyr Pro 
625                 630                 635                 640 


Asn Trp Ala Ile Gly Leu Gly Trp Ser Leu Ala Leu Ser Ser Met Leu 
                645                 650                 655     


Cys Val Pro Leu Val Ile Val Ile Arg Leu Cys Gln Thr Glu Gly Pro 
            660                 665                 670         


Phe Leu Val Arg Val Lys Tyr Leu Leu Thr Pro Arg Glu Pro Asn Arg 
        675                 680                 685             


Trp Ala Val Glu Arg Glu Gly Ala Thr Pro Tyr Asn Ser Arg Thr Val 
    690                 695                 700                 


Met Asn Gly Ala Leu Val Lys Pro Thr His Ile Ile Val Glu Thr Met 
705                 710                 715                 720 


Met 
    


<210>  3969
<211>  252
<212>  PRT
<213>  homo sapiens

<400>  3969

Met Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala Gly Ser Gly Lys Arg 
1               5                   10                  15      


Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val Gln Ile Leu Arg Asp 
            20                  25                  30          


Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro Ser Glu Gln Glu Lys 
        35                  40                  45              


Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr Leu Gln Val Cys Asn 
    50                  55                  60                  


Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro Asp Met Leu Arg Lys 
65                  70                  75                  80  


Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile Ser Arg Arg Gly Ala Lys 
                85                  90                  95      


Ile Ser Glu Thr Ser Ser Val Glu Ser Val Met Gly Ile Lys Asn Phe 
            100                 105                 110         


Met Pro Ala Leu Glu Glu Thr Pro Phe His Ser Cys Thr Ala Gly Pro 
        115                 120                 125             


Asn Pro Thr Leu Gly Arg Pro Leu Ser Pro Lys Pro Ser Ser Pro Gly 
    130                 135                 140                 


Ser Val Leu Ala Arg Pro Ser Val Ile Cys His Thr Thr Val Thr Ala 
145                 150                 155                 160 


Leu Lys Asp Val Pro Phe Ser Leu Cys Gln Ser Val Gly Val Gly Gln 
                165                 170                 175     


Asn Thr Asp Ile Gln Gln Ile Ala Ala Lys Asn Phe Thr Asp Thr Ser 
            180                 185                 190         


Leu Met Tyr Pro Glu Asp Thr Cys Lys Ser Gly Pro Ser Thr Asn Thr 
        195                 200                 205             


Gln Ser Gly Leu Phe Asn Thr Pro Pro Pro Thr Pro Pro Asp Leu Asn 
    210                 215                 220                 


Gln Asp Phe Ser Gly Phe Gln Leu Leu Val Asp Val Ala Leu Lys Arg 
225                 230                 235                 240 


Ala Ala Glu Met Glu Leu Gln Ala Lys Leu Thr Ala 
                245                 250         


<210>  3970
<211>  472
<212>  PRT
<213>  homo sapiens

<400>  3970

Met Met Gln His Ala Ser Pro Ala Pro Ala Leu Thr Met Met Ala Thr 
1               5                   10                  15      


Gln Asn Val Pro Pro Pro Pro Tyr Gln Asp Ser Pro Gln Met Thr Ala 
            20                  25                  30          


Thr Ala Gln Pro Pro Ser Lys Ala Gln Ala Val His Ile Ser Ala Pro 
        35                  40                  45              


Ser Ala Ala Ala Ser Thr Pro Val Pro Ser Ala Pro Ile Asp Pro Gln 
    50                  55                  60                  


Ala Gln Leu Glu Ala Asp Lys Arg Ala Val Tyr Arg His Pro Leu Phe 
65                  70                  75                  80  


Pro Leu Leu Thr Leu Leu Phe Glu Lys Cys Glu Gln Ala Thr Gln Gly 
                85                  90                  95      


Ser Glu Cys Ile Thr Ser Ala Ser Phe Asp Val Asp Ile Glu Asn Phe 
            100                 105                 110         


Val His Gln Gln Glu Gln Glu His Lys Pro Phe Phe Ser Asp Asp Pro 
        115                 120                 125             


Glu Leu Asp Asn Leu Met Val Lys Ala Ile Gln Val Leu Arg Ile His 
    130                 135                 140                 


Leu Leu Glu Leu Glu Lys Val Asn Glu Leu Cys Lys Asp Phe Cys Asn 
145                 150                 155                 160 


Arg Tyr Ile Thr Cys Leu Lys Thr Lys Met His Ser Asp Asn Leu Leu 
                165                 170                 175     


Arg Asn Asp Leu Gly Gly Pro Tyr Ser Pro Asn Gln Pro Ser Ile Asn 
            180                 185                 190         


Leu His Ser Gln Asp Leu Leu Gln Asn Ser Pro Asn Ser Met Ser Gly 
        195                 200                 205             


Val Ser Asn Asn Pro Gln Gly Ile Val Val Pro Ala Ser Ala Leu Gln 
    210                 215                 220                 


Gln Gly Asn Ile Ala Met Thr Thr Val Asn Ser Gln Val Val Ser Gly 
225                 230                 235                 240 


Gly Ala Leu Tyr Gln Pro Val Thr Met Val Thr Ser Gln Gly Gln Val 
                245                 250                 255     


Val Thr Gln Ala Ile Pro Gln Gly Ala Ile Gln Ile Gln Asn Thr Gln 
            260                 265                 270         


Val Asn Leu Asp Leu Thr Ser Leu Leu Asp Asn Glu Asp Lys Lys Ser 
        275                 280                 285             


Lys Asn Lys Arg Gly Val Leu Pro Lys His Ala Thr Asn Ile Met Arg 
    290                 295                 300                 


Ser Trp Leu Phe Gln His Leu Met His Pro Tyr Pro Thr Glu Asp Glu 
305                 310                 315                 320 


Lys Arg Gln Ile Ala Ala Gln Thr Asn Leu Thr Leu Leu Gln Val Asn 
                325                 330                 335     


Asn Trp Phe Ile Asn Ala Arg Arg Arg Ile Leu Gln Pro Met Leu Asp 
            340                 345                 350         


Ala Ser Asn Pro Asp Pro Ala Pro Lys Ala Lys Lys Ile Lys Ser Gln 
        355                 360                 365             


His Arg Pro Thr Gln Arg Phe Trp Pro Asn Ser Ile Ala Ala Gly Val 
    370                 375                 380                 


Leu Gln Gln Gln Gly Gly Ala Pro Gly Thr Asn Pro Asp Gly Ser Ile 
385                 390                 395                 400 


Asn Leu Asp Asn Leu Gln Ser Leu Ser Ser Asp Ser Ala Thr Met Ala 
                405                 410                 415     


Met Gln Gln Ala Met Met Ala Ala His Asp Asp Ser Leu Asp Gly Thr 
            420                 425                 430         


Glu Glu Glu Asp Glu Asp Glu Met Glu Glu Glu Glu Glu Glu Glu Leu 
        435                 440                 445             


Glu Glu Glu Val Asp Glu Leu Gln Thr Thr Asn Val Ser Asp Leu Gly 
    450                 455                 460                 


Leu Glu His Ser Asp Ser Leu Glu 
465                 470         


<210>  3971
<211>  500
<212>  PRT
<213>  homo sapiens

<400>  3971

Met Ala Thr Val Ile Pro Gly Asp Leu Ser Glu Val Arg Asp Thr Gln 
1               5                   10                  15      


Lys Val Pro Ser Gly Lys Arg Lys Arg Gly Glu Thr Lys Pro Arg Lys 
            20                  25                  30          


Asn Phe Pro Cys Gln Leu Cys Asp Lys Ala Phe Asn Ser Val Glu Lys 
        35                  40                  45              


Leu Lys Val His Ser Tyr Ser His Thr Gly Glu Arg Pro Tyr Lys Cys 
    50                  55                  60                  


Ile Gln Gln Asp Cys Thr Lys Ala Phe Val Ser Lys Tyr Lys Leu Gln 
65                  70                  75                  80  


Arg His Met Ala Thr His Ser Pro Glu Lys Thr His Lys Cys Asn Tyr 
                85                  90                  95      


Cys Glu Lys Met Phe His Arg Lys Asp His Leu Lys Asn His Leu His 
            100                 105                 110         


Thr His Asp Pro Asn Lys Glu Thr Phe Lys Cys Glu Glu Cys Gly Lys 
        115                 120                 125             


Asn Tyr Asn Thr Lys Leu Gly Phe Lys Arg His Leu Ala Leu His Ala 
    130                 135                 140                 


Ala Thr Ser Gly Asp Leu Thr Cys Lys Val Cys Leu Gln Thr Phe Glu 
145                 150                 155                 160 


Ser Thr Gly Val Leu Leu Glu His Leu Lys Ser His Ala Gly Lys Ser 
                165                 170                 175     


Ser Gly Gly Val Lys Glu Lys Lys His Gln Cys Glu His Cys Asp Arg 
            180                 185                 190         


Arg Phe Tyr Thr Arg Lys Asp Val Arg Arg His Met Val Val His Thr 
        195                 200                 205             


Gly Arg Lys Asp Phe Leu Cys Gln Tyr Cys Ala Gln Arg Phe Gly Arg 
    210                 215                 220                 


Lys Asp His Leu Thr Arg His Met Lys Lys Ser His Asn Gln Glu Leu 
225                 230                 235                 240 


Leu Lys Val Lys Thr Glu Pro Val Asp Phe Leu Asp Pro Phe Thr Cys 
                245                 250                 255     


Asn Val Ser Val Pro Ile Lys Asp Glu Leu Leu Pro Val Met Ser Leu 
            260                 265                 270         


Pro Ser Ser Glu Leu Leu Ser Lys Pro Phe Thr Asn Thr Leu Gln Leu 
        275                 280                 285             


Asn Leu Tyr Asn Thr Pro Phe Gln Ser Met Gln Ser Ser Gly Ser Ala 
    290                 295                 300                 


His Gln Met Ile Thr Thr Leu Pro Leu Gly Met Thr Cys Pro Ile Asp 
305                 310                 315                 320 


Met Asp Thr Val His Pro Ser His His Leu Ser Phe Lys Tyr Pro Phe 
                325                 330                 335     


Ser Ser Thr Ser Tyr Ala Ile Ser Ile Pro Glu Lys Glu Gln Pro Leu 
            340                 345                 350         


Lys Gly Glu Ile Glu Ser Tyr Leu Met Glu Leu Gln Gly Gly Val Pro 
        355                 360                 365             


Ser Ser Ser Gln Asp Ser Gln Ala Ser Ser Ser Ser Lys Leu Gly Leu 
    370                 375                 380                 


Asp Pro Gln Ile Gly Ser Leu Asp Asp Gly Ala Gly Asp Leu Ser Leu 
385                 390                 395                 400 


Ser Lys Ser Ser Ile Ser Ile Ser Asp Pro Leu Asn Thr Pro Ala Leu 
                405                 410                 415     


Asp Phe Ser Gln Leu Phe Asn Phe Ile Pro Leu Asn Gly Pro Pro Tyr 
            420                 425                 430         


Asn Pro Leu Ser Val Gly Ser Leu Gly Met Ser Tyr Ser Gln Glu Glu 
        435                 440                 445             


Ala His Ser Ser Val Ser Gln Leu Pro Pro Gln Thr Gln Asp Leu Gln 
    450                 455                 460                 


Asp Pro Ala Asn Thr Ile Gly Leu Gly Ser Leu His Ser Leu Ser Ala 
465                 470                 475                 480 


Ala Phe Thr Ser Ser Leu Ser Thr Ser Thr Thr Leu Pro Arg Phe His 
                485                 490                 495     


Gln Ala Phe Gln 
            500 


<210>  3972
<211>  297
<212>  PRT
<213>  homo sapiens

<400>  3972

Met Glu Asp Tyr Thr Lys Ile Glu Lys Ile Gly Glu Gly Thr Tyr Gly 
1               5                   10                  15      


Val Val Tyr Lys Gly Arg His Lys Thr Thr Gly Gln Val Val Ala Met 
            20                  25                  30          


Lys Lys Ile Arg Leu Glu Ser Glu Glu Glu Gly Val Pro Ser Thr Ala 
        35                  40                  45              


Ile Arg Glu Ile Ser Leu Leu Lys Glu Leu Arg His Pro Asn Ile Val 
    50                  55                  60                  


Ser Leu Gln Asp Val Leu Met Gln Asp Ser Arg Leu Tyr Leu Ile Phe 
65                  70                  75                  80  


Glu Phe Leu Ser Met Asp Leu Lys Lys Tyr Leu Asp Ser Ile Pro Pro 
                85                  90                  95      


Gly Gln Tyr Met Asp Ser Ser Leu Val Lys Ser Tyr Leu Tyr Gln Ile 
            100                 105                 110         


Leu Gln Gly Ile Val Phe Cys His Ser Arg Arg Val Leu His Arg Asp 
        115                 120                 125             


Leu Lys Pro Gln Asn Leu Leu Ile Asp Asp Lys Gly Thr Ile Lys Leu 
    130                 135                 140                 


Ala Asp Phe Gly Leu Ala Arg Ala Phe Gly Ile Pro Ile Arg Val Tyr 
145                 150                 155                 160 


Thr His Glu Val Val Thr Leu Trp Tyr Arg Ser Pro Glu Val Leu Leu 
                165                 170                 175     


Gly Ser Ala Arg Tyr Ser Thr Pro Val Asp Ile Trp Ser Ile Gly Thr 
            180                 185                 190         


Ile Phe Ala Glu Leu Ala Thr Lys Lys Pro Leu Phe His Gly Asp Ser 
        195                 200                 205             


Glu Ile Asp Gln Leu Phe Arg Ile Phe Arg Ala Leu Gly Thr Pro Asn 
    210                 215                 220                 


Asn Glu Val Trp Pro Glu Val Glu Ser Leu Gln Asp Tyr Lys Asn Thr 
225                 230                 235                 240 


Phe Pro Lys Trp Lys Pro Gly Ser Leu Ala Ser His Val Lys Asn Leu 
                245                 250                 255     


Asp Glu Asn Gly Leu Asp Leu Leu Ser Lys Met Leu Ile Tyr Asp Pro 
            260                 265                 270         


Ala Lys Arg Ile Ser Gly Lys Met Ala Leu Asn His Pro Tyr Phe Asn 
        275                 280                 285             


Asp Leu Asp Asn Gln Ile Lys Lys Met 
    290                 295         


<210>  3973
<211>  537
<212>  PRT
<213>  homo sapiens

<400>  3973

Met Glu Arg Val Asn Asp Ala Ser Cys Gly Pro Ser Gly Cys Tyr Thr 
1               5                   10                  15      


Tyr Gln Val Ser Arg His Ser Thr Glu Met Leu His Asn Leu Asn Gln 
            20                  25                  30          


Gln Arg Lys Asn Gly Gly Arg Phe Cys Asp Val Leu Leu Arg Val Gly 
        35                  40                  45              


Asp Glu Ser Phe Pro Ala His Arg Ala Val Leu Ala Ala Cys Ser Glu 
    50                  55                  60                  


Tyr Phe Glu Ser Val Phe Ser Ala Gln Leu Gly Asp Gly Gly Ala Ala 
65                  70                  75                  80  


Asp Gly Gly Pro Ala Asp Val Gly Gly Ala Thr Ala Ala Pro Gly Gly 
                85                  90                  95      


Gly Ala Gly Gly Ser Arg Glu Leu Glu Met His Thr Ile Ser Ser Lys 
            100                 105                 110         


Val Phe Gly Asp Ile Leu Asp Phe Ala Tyr Thr Ser Arg Ile Val Val 
        115                 120                 125             


Arg Leu Glu Ser Phe Pro Glu Leu Met Thr Ala Ala Lys Phe Leu Leu 
    130                 135                 140                 


Met Arg Ser Val Ile Glu Ile Cys Gln Glu Val Ile Lys Gln Ser Asn 
145                 150                 155                 160 


Val Gln Ile Leu Val Pro Pro Ala Arg Ala Asp Ile Met Leu Phe Arg 
                165                 170                 175     


Pro Pro Gly Thr Ser Asp Leu Gly Phe Pro Leu Asp Met Thr Asn Gly 
            180                 185                 190         


Ala Ala Leu Ala Ala Asn Ser Asn Gly Ile Ala Gly Ser Met Gln Pro 
        195                 200                 205             


Glu Glu Glu Ala Ala Arg Ala Ala Gly Ala Ala Ile Ala Gly Gln Ala 
    210                 215                 220                 


Ser Leu Pro Val Leu Pro Gly Val Asp Arg Leu Pro Met Val Ala Gly 
225                 230                 235                 240 


Pro Leu Ser Pro Gln Leu Leu Thr Ser Pro Phe Pro Ser Val Ala Ser 
                245                 250                 255     


Ser Ala Pro Pro Leu Thr Gly Lys Arg Gly Arg Gly Arg Pro Arg Lys 
            260                 265                 270         


Ala Asn Leu Leu Asp Ser Met Phe Gly Ser Pro Gly Gly Leu Arg Glu 
        275                 280                 285             


Ala Gly Ile Leu Pro Cys Gly Leu Cys Gly Lys Val Phe Thr Asp Ala 
    290                 295                 300                 


Asn Arg Leu Arg Gln His Glu Ala Gln His Gly Val Thr Ser Leu Gln 
305                 310                 315                 320 


Leu Gly Tyr Ile Asp Leu Pro Pro Pro Arg Leu Gly Glu Asn Gly Leu 
                325                 330                 335     


Pro Ile Ser Glu Asp Pro Asp Gly Pro Arg Lys Arg Ser Arg Thr Arg 
            340                 345                 350         


Lys Gln Val Ala Cys Glu Ile Cys Gly Lys Ile Phe Arg Asp Val Tyr 
        355                 360                 365             


His Leu Asn Arg His Lys Leu Ser His Ser Gly Glu Lys Pro Tyr Ser 
    370                 375                 380                 


Cys Pro Val Cys Gly Leu Arg Phe Lys Arg Lys Asp Arg Met Ser Tyr 
385                 390                 395                 400 


His Val Arg Ser His Asp Gly Ser Val Gly Lys Pro Tyr Ile Cys Gln 
                405                 410                 415     


Ser Cys Gly Lys Gly Phe Ser Arg Pro Asp His Leu Asn Gly His Ile 
            420                 425                 430         


Lys Gln Val His Thr Ser Glu Arg Pro His Lys Cys Gln Thr Cys Asn 
        435                 440                 445             


Ala Ser Phe Ala Thr Arg Asp Arg Leu Arg Ser His Leu Ala Cys His 
    450                 455                 460                 


Glu Asp Lys Val Pro Cys Gln Val Cys Gly Lys Tyr Leu Arg Ala Ala 
465                 470                 475                 480 


Tyr Met Ala Asp His Leu Lys Lys His Ser Glu Gly Pro Ser Asn Phe 
                485                 490                 495     


Cys Ser Ile Cys Asn Arg Gly Leu Gln Ala Pro Gly Ala His Pro Glu 
            500                 505                 510         


Trp Gly Ser Ser Val Pro Leu Arg Gln Asp Leu Trp Gln Gln Arg Arg 
        515                 520                 525             


Pro Glu Met Leu Thr Ser Gly Ser Asp 
    530                 535         


<210>  3974
<211>  90
<212>  PRT
<213>  homo sapiens

<400>  3974

Met Ala Asp Val Glu Asp Gly Glu Glu Thr Cys Ala Leu Ala Ser His 
1               5                   10                  15      


Ser Gly Ser Ser Gly Ser Lys Ser Gly Gly Asp Lys Met Phe Ser Leu 
            20                  25                  30          


Lys Lys Trp Asn Ala Val Ala Met Trp Ser Trp Asp Val Glu Cys Asp 
        35                  40                  45              


Thr Cys Ala Ile Cys Arg Val Gln Met Pro Val Leu Asp Val Lys Leu 
    50                  55                  60                  


Lys Thr Asn Lys Arg Thr Val Leu Trp Ser Gly Glu Asn Val Ile Ile 
65                  70                  75                  80  


Pro Ser Thr Thr Ala Ala Cys Pro Cys Gly 
                85                  90  


<210>  3975
<211>  1378
<212>  PRT
<213>  homo sapiens

<400>  3975

Met Ser Leu Leu Met Phe Thr Gln Leu Leu Leu Cys Gly Phe Leu Tyr 
1               5                   10                  15      


Val Arg Val Asp Gly Ser Arg Leu Arg Gln Glu Asp Phe Pro Pro Arg 
            20                  25                  30          


Ile Val Glu His Pro Ser Asp Val Ile Val Ser Lys Gly Glu Pro Thr 
        35                  40                  45              


Thr Leu Asn Cys Lys Ala Glu Gly Arg Pro Thr Pro Thr Ile Glu Trp 
    50                  55                  60                  


Tyr Lys Asp Gly Glu Arg Val Glu Thr Asp Lys Asp Asp Pro Arg Ser 
65                  70                  75                  80  


His Arg Met Leu Leu Pro Ser Gly Ser Leu Phe Phe Leu Arg Ile Val 
                85                  90                  95      


His Gly Arg Arg Ser Lys Pro Asp Glu Gly Ser Tyr Val Cys Val Ala 
            100                 105                 110         


Arg Asn Tyr Leu Gly Glu Ala Val Ser Arg Asn Ala Ser Leu Glu Val 
        115                 120                 125             


Ala Leu Leu Arg Asp Asp Phe Arg Gln Asn Pro Thr Asp Val Val Val 
    130                 135                 140                 


Ala Ala Gly Glu Pro Ala Ile Leu Glu Cys Gln Pro Pro Arg Gly His 
145                 150                 155                 160 


Pro Glu Pro Thr Ile Tyr Trp Lys Lys Asp Lys Val Arg Ile Asp Asp 
                165                 170                 175     


Lys Glu Glu Arg Ile Ser Ile Arg Gly Gly Lys Leu Met Ile Ser Asn 
            180                 185                 190         


Thr Arg Lys Ser Asp Ala Gly Met Tyr Thr Cys Val Gly Thr Asn Met 
        195                 200                 205             


Val Gly Glu Arg Asp Ser Asp Pro Ala Glu Leu Thr Val Phe Glu Arg 
    210                 215                 220                 


Pro Thr Phe Leu Arg Arg Pro Ile Asn Gln Val Val Leu Glu Glu Glu 
225                 230                 235                 240 


Ala Val Glu Phe Arg Cys Gln Val Gln Gly Asp Pro Gln Pro Thr Val 
                245                 250                 255     


Arg Trp Lys Lys Asp Asp Ala Asp Leu Pro Arg Gly Arg Tyr Asp Ile 
            260                 265                 270         


Lys Asp Asp Tyr Thr Leu Arg Ile Lys Lys Thr Met Ser Thr Asp Glu 
        275                 280                 285             


Gly Thr Tyr Met Cys Ile Ala Glu Asn Arg Val Gly Lys Met Glu Ala 
    290                 295                 300                 


Ser Ala Thr Leu Thr Val Arg Ala Pro Pro Gln Phe Val Val Arg Pro 
305                 310                 315                 320 


Arg Asp Gln Ile Val Ala Gln Gly Arg Thr Val Thr Phe Pro Cys Glu 
                325                 330                 335     


Thr Lys Gly Asn Pro Gln Pro Ala Val Phe Trp Gln Lys Glu Gly Ser 
            340                 345                 350         


Gln Asn Leu Leu Phe Pro Asn Gln Pro Gln Gln Pro Asn Ser Arg Cys 
        355                 360                 365             


Ser Val Ser Pro Thr Gly Asp Leu Thr Ile Thr Asn Ile Gln Arg Ser 
    370                 375                 380                 


Asp Ala Gly Tyr Tyr Ile Cys Gln Ala Leu Thr Val Ala Gly Ser Ile 
385                 390                 395                 400 


Leu Ala Lys Ala Gln Leu Glu Val Thr Asp Val Leu Thr Asp Arg Pro 
                405                 410                 415     


Pro Pro Ile Ile Leu Gln Gly Pro Ala Asn Gln Thr Leu Ala Val Asp 
            420                 425                 430         


Gly Thr Ala Leu Leu Lys Cys Lys Ala Thr Gly Asp Pro Leu Pro Val 
        435                 440                 445             


Ile Ser Trp Leu Lys Glu Gly Phe Thr Phe Pro Gly Arg Asp Pro Arg 
    450                 455                 460                 


Ala Thr Ile Gln Glu Gln Gly Thr Leu Gln Ile Lys Asn Leu Arg Ile 
465                 470                 475                 480 


Ser Asp Thr Gly Thr Tyr Thr Cys Val Ala Thr Ser Ser Ser Gly Glu 
                485                 490                 495     


Thr Ser Trp Ser Ala Val Leu Asp Val Thr Glu Ser Gly Ala Thr Ile 
            500                 505                 510         


Ser Lys Asn Tyr Asp Leu Ser Asp Leu Pro Gly Pro Pro Ser Lys Pro 
        515                 520                 525             


Gln Val Thr Asp Val Thr Lys Asn Ser Val Thr Leu Ser Trp Gln Pro 
    530                 535                 540                 


Gly Thr Pro Gly Thr Leu Pro Ala Ser Ala Tyr Ile Ile Glu Ala Phe 
545                 550                 555                 560 


Ser Gln Ser Val Ser Asn Ser Trp Gln Thr Val Ala Asn His Val Lys 
                565                 570                 575     


Thr Thr Leu Tyr Thr Val Arg Gly Leu Arg Pro Asn Thr Ile Tyr Leu 
            580                 585                 590         


Phe Met Val Arg Ala Ile Asn Pro Gln Gly Leu Ser Asp Pro Ser Pro 
        595                 600                 605             


Met Ser Asp Pro Val Arg Thr Gln Asp Ile Ser Pro Pro Ala Gln Gly 
    610                 615                 620                 


Val Asp His Arg Gln Val Gln Lys Glu Leu Gly Asp Val Leu Val Arg 
625                 630                 635                 640 


Leu His Asn Pro Val Val Leu Thr Pro Thr Thr Val Gln Val Thr Trp 
                645                 650                 655     


Thr Val Asp Arg Gln Pro Gln Phe Ile Gln Gly Tyr Arg Val Met Tyr 
            660                 665                 670         


Arg Gln Thr Ser Gly Leu Gln Ala Thr Ser Ser Trp Gln Asn Leu Asp 
        675                 680                 685             


Ala Lys Val Pro Thr Glu Arg Ser Ala Val Leu Val Asn Leu Lys Lys 
    690                 695                 700                 


Gly Val Thr Tyr Glu Ile Lys Val Arg Pro Tyr Phe Asn Glu Phe Gln 
705                 710                 715                 720 


Gly Met Asp Ser Glu Ser Lys Thr Val Arg Thr Thr Glu Glu Ala Pro 
                725                 730                 735     


Ser Ala Pro Pro Gln Ser Val Thr Val Leu Thr Val Gly Ser Tyr Asn 
            740                 745                 750         


Ser Thr Ser Ile Ser Val Ser Trp Asp Pro Pro Pro Pro Asp His Gln 
        755                 760                 765             


Asn Gly Ile Ile Gln Glu Tyr Lys Ile Trp Cys Leu Gly Asn Glu Thr 
    770                 775                 780                 


Arg Phe His Ile Asn Lys Thr Val Asp Ala Ala Ile Arg Ser Val Ile 
785                 790                 795                 800 


Ile Gly Gly Leu Phe Pro Gly Ile Gln Tyr Arg Val Glu Val Ala Ala 
                805                 810                 815     


Ser Thr Ser Ala Gly Val Gly Val Lys Ser Glu Pro Gln Pro Ile Ile 
            820                 825                 830         


Ile Gly Arg Arg Asn Glu Val Val Ile Thr Glu Asn Asn Asn Ser Ile 
        835                 840                 845             


Thr Glu Gln Ile Thr Asp Val Val Lys Gln Pro Ala Phe Ile Ala Gly 
    850                 855                 860                 


Ile Gly Gly Ala Cys Trp Val Ile Leu Met Gly Phe Ser Ile Trp Leu 
865                 870                 875                 880 


Tyr Trp Arg Arg Lys Lys Arg Lys Gly Leu Ser Asn Tyr Ala Val Thr 
                885                 890                 895     


Phe Gln Arg Gly Asp Gly Gly Leu Met Ser Asn Gly Ser Arg Pro Gly 
            900                 905                 910         


Leu Leu Asn Ala Gly Asp Pro Ser Tyr Pro Trp Leu Ala Asp Ser Trp 
        915                 920                 925             


Pro Ala Thr Ser Leu Pro Val Asn Asn Ser Asn Ser Gly Pro Asn Glu 
    930                 935                 940                 


Ile Gly Asn Phe Gly Arg Gly Asp Val Leu Pro Pro Val Pro Gly Gln 
945                 950                 955                 960 


Gly Asp Lys Thr Ala Thr Met Leu Ser Asp Gly Ala Ile Tyr Ser Ser 
                965                 970                 975     


Ile Asp Phe Thr Thr Lys Thr Ser Tyr Asn Ser Ser Ser Gln Ile Thr 
            980                 985                 990         


Gln Ala Thr Pro Tyr Ala Thr Thr  Gln Ile Leu His Ser  Asn Ser Ile 
        995                 1000                 1005             


His Glu  Leu Ala Val Asp Leu  Pro Asp Pro Gln Trp  Lys Ser Ser 
    1010                 1015                 1020             


Ile Gln  Gln Lys Thr Asp Leu  Met Gly Phe Gly Tyr  Ser Leu Pro 
    1025                 1030                 1035             


Asp Gln  Asn Lys Gly Asn Asn  Gly Gly Lys Gly Gly  Lys Lys Lys 
    1040                 1045                 1050             


Lys Asn  Lys Asn Ser Ser Lys  Pro Gln Lys Asn Asn  Gly Ser Thr 
    1055                 1060                 1065             


Trp Ala  Asn Val Pro Leu Pro  Pro Pro Pro Val Gln  Pro Leu Pro 
    1070                 1075                 1080             


Gly Thr  Glu Leu Glu His Tyr  Ala Val Glu Gln Gln  Glu Asn Gly 
    1085                 1090                 1095             


Tyr Asp  Ser Asp Ser Trp Cys  Pro Pro Leu Pro Val  Gln Thr Tyr 
    1100                 1105                 1110             


Leu His  Gln Gly Leu Glu Asp  Glu Leu Glu Glu Asp  Asp Asp Arg 
    1115                 1120                 1125             


Val Pro  Thr Pro Pro Val Arg  Gly Val Ala Ser Ser  Pro Ala Ile 
    1130                 1135                 1140             


Ser Phe  Gly Gln Gln Ser Thr  Ala Thr Leu Thr Pro  Ser Pro Arg 
    1145                 1150                 1155             


Glu Glu  Met Gln Pro Met Leu  Gln Ala His Leu Asp  Glu Leu Thr 
    1160                 1165                 1170             


Arg Ala  Tyr Gln Phe Asp Ile  Ala Lys Gln Thr Trp  His Ile Gln 
    1175                 1180                 1185             


Ser Asn  Asn Gln Pro Pro Gln  Pro Pro Val Pro Pro  Leu Gly Tyr 
    1190                 1195                 1200             


Val Ser  Gly Ala Leu Ile Ser  Asp Leu Glu Thr Asp  Val Ala Asp 
    1205                 1210                 1215             


Asp Asp  Ala Asp Asp Glu Glu  Glu Ala Leu Glu Ile  Pro Arg Pro 
    1220                 1225                 1230             


Leu Arg  Ala Leu Asp Gln Thr  Pro Gly Ser Ser Met  Asp Asn Leu 
    1235                 1240                 1245             


Asp Ser  Ser Val Thr Gly Lys  Ala Phe Thr Ser Ser  Gln Arg Pro 
    1250                 1255                 1260             


Arg Pro  Thr Ser Pro Phe Ser  Thr Asp Ser Asn Thr  Ser Ala Ala 
    1265                 1270                 1275             


Leu Ser  Gln Ser Gln Arg Pro  Arg Pro Thr Lys Lys  His Lys Gly 
    1280                 1285                 1290             


Gly Arg  Met Asp Gln Gln Pro  Ala Leu Pro His Arg  Arg Glu Gly 
    1295                 1300                 1305             


Met Thr  Asp Glu Glu Ala Leu  Val Pro Tyr Ser Lys  Pro Ser Phe 
    1310                 1315                 1320             


Pro Ser  Pro Gly Gly His Ser  Ser Ser Gly Thr Ala  Ser Ser Lys 
    1325                 1330                 1335             


Gly Ser  Thr Gly Pro Arg Lys  Thr Glu Val Leu Arg  Ala Gly His 
    1340                 1345                 1350             


Gln Arg  Asn Ala Ser Asp Leu  Leu Asp Ile Gly Tyr  Met Gly Ser 
    1355                 1360                 1365             


Asn Ser  Gln Gly Gln Phe Thr  Gly Glu Leu 
    1370                 1375             


<210>  3976
<211>  140
<212>  PRT
<213>  homo sapiens

<400>  3976

Met Ala Glu Glu Pro Gln Ser Val Leu Gln Leu Pro Thr Ser Ile Ala 
1               5                   10                  15      


Ala Gly Gly Glu Gly Leu Thr Asp Val Ser Pro Glu Thr Thr Thr Pro 
            20                  25                  30          


Glu Pro Pro Ser Ser Ala Ala Val Ser Pro Gly Thr Glu Glu Pro Ala 
        35                  40                  45              


Gly Asp Thr Lys Lys Lys Ile Asp Ile Leu Leu Lys Ala Val Gly Asp 
    50                  55                  60                  


Thr Pro Ile Met Lys Thr Lys Lys Trp Ala Val Glu Arg Thr Arg Thr 
65                  70                  75                  80  


Ile Gln Gly Leu Ile Asp Phe Ile Lys Lys Phe Leu Lys Leu Val Ala 
                85                  90                  95      


Ser Glu Gln Leu Phe Ile Tyr Val Asn Gln Ser Phe Ala Pro Ser Pro 
            100                 105                 110         


Asp Gln Glu Val Gly Thr Leu Tyr Glu Cys Phe Gly Ser Asp Gly Lys 
        115                 120                 125             


Leu Val Leu His Tyr Cys Lys Ser Gln Ala Trp Gly 
    130                 135                 140 


<210>  3977
<211>  1342
<212>  PRT
<213>  homo sapiens

<400>  3977

Met Asp Thr Lys Leu Met Cys Leu Leu Phe Phe Phe Ser Leu Pro Pro 
1               5                   10                  15      


Leu Leu Val Ser Asn His Thr Gly Arg Ile Lys Val Val Phe Thr Pro 
            20                  25                  30          


Ser Ile Cys Lys Val Thr Cys Thr Lys Gly Ser Cys Gln Asn Ser Cys 
        35                  40                  45              


Glu Lys Gly Asn Thr Thr Thr Leu Ile Ser Glu Asn Gly His Ala Ala 
    50                  55                  60                  


Asp Thr Leu Thr Ala Thr Asn Phe Arg Val Val Ile Cys His Leu Pro 
65                  70                  75                  80  


Cys Met Asn Gly Gly Gln Cys Ser Ser Arg Asp Lys Cys Gln Cys Pro 
                85                  90                  95      


Pro Asn Phe Thr Gly Lys Leu Cys Gln Ile Pro Val His Gly Ala Ser 
            100                 105                 110         


Val Pro Lys Leu Tyr Gln His Ser Gln Gln Pro Gly Lys Ala Leu Gly 
        115                 120                 125             


Thr His Val Ile His Ser Thr His Thr Leu Pro Leu Thr Val Thr Ser 
    130                 135                 140                 


Gln Gln Gly Val Lys Val Lys Phe Pro Pro Asn Ile Val Asn Ile His 
145                 150                 155                 160 


Val Lys His Pro Pro Glu Ala Ser Val Gln Ile His Gln Val Ser Arg 
                165                 170                 175     


Ile Asp Gly Pro Thr Gly Gln Lys Thr Lys Glu Ala Gln Pro Gly Gln 
            180                 185                 190         


Ser Gln Val Ser Tyr Gln Gly Leu Pro Val Gln Lys Thr Gln Thr Ile 
        195                 200                 205             


His Ser Thr Tyr Ser His Gln Gln Val Ile Pro His Val Tyr Pro Val 
    210                 215                 220                 


Ala Ala Lys Thr Gln Leu Gly Arg Cys Phe Gln Glu Thr Ile Gly Ser 
225                 230                 235                 240 


Gln Cys Gly Lys Ala Leu Pro Gly Leu Ser Lys Gln Glu Asp Cys Cys 
                245                 250                 255     


Gly Thr Val Gly Thr Ser Trp Gly Phe Asn Lys Cys Gln Lys Cys Pro 
            260                 265                 270         


Lys Lys Pro Ser Tyr His Gly Tyr Asn Gln Met Met Glu Cys Leu Pro 
        275                 280                 285             


Gly Tyr Lys Arg Val Asn Asn Thr Phe Cys Gln Asp Ile Asn Glu Cys 
    290                 295                 300                 


Gln Leu Gln Gly Val Cys Pro Asn Gly Glu Cys Leu Asn Thr Met Gly 
305                 310                 315                 320 


Ser Tyr Arg Cys Thr Cys Lys Ile Gly Phe Gly Pro Asp Pro Thr Phe 
                325                 330                 335     


Ser Ser Cys Val Pro Asp Pro Pro Val Ile Ser Glu Glu Lys Gly Pro 
            340                 345                 350         


Cys Tyr Arg Leu Val Ser Ser Gly Arg Gln Cys Met His Pro Leu Ser 
        355                 360                 365             


Val His Leu Thr Lys Gln Leu Cys Cys Cys Ser Val Gly Lys Ala Trp 
    370                 375                 380                 


Gly Pro His Cys Glu Lys Cys Pro Leu Pro Gly Thr Ala Lys Glu Glu 
385                 390                 395                 400 


Pro Val Glu Ala Leu Thr Phe Ser Arg Glu His Gly Pro Gly Val Ala 
                405                 410                 415     


Glu Pro Glu Val Ala Thr Ala Pro Pro Glu Lys Glu Ile Pro Ser Leu 
            420                 425                 430         


Asp Gln Glu Lys Thr Lys Leu Glu Pro Gly Gln Pro Gln Leu Ser Pro 
        435                 440                 445             


Gly Ile Ser Thr Ile His Leu His Pro Gln Phe Pro Val Val Ile Glu 
    450                 455                 460                 


Lys Thr Ser Pro Pro Val Pro Val Glu Val Ala Pro Glu Ala Ser Thr 
465                 470                 475                 480 


Ser Ser Ala Ser Gln Val Ile Ala Pro Thr Gln Val Thr Glu Ile Asn 
                485                 490                 495     


Glu Cys Thr Val Asn Pro Asp Ile Cys Gly Ala Gly His Cys Ile Asn 
            500                 505                 510         


Leu Pro Val Arg Tyr Thr Cys Ile Cys Tyr Glu Gly Tyr Arg Phe Ser 
        515                 520                 525             


Glu Gln Gln Arg Lys Cys Val Asp Ile Asp Glu Cys Thr Gln Val Gln 
    530                 535                 540                 


His Leu Cys Ser Gln Gly Arg Cys Glu Asn Thr Glu Gly Ser Phe Leu 
545                 550                 555                 560 


Cys Ile Cys Pro Ala Gly Phe Met Ala Ser Glu Glu Gly Thr Asn Cys 
                565                 570                 575     


Ile Asp Val Asp Glu Cys Leu Arg Pro Asp Val Cys Gly Glu Gly His 
            580                 585                 590         


Cys Val Asn Thr Val Gly Ala Phe Arg Cys Glu Tyr Cys Asp Ser Gly 
        595                 600                 605             


Tyr Arg Met Thr Gln Arg Gly Arg Cys Glu Asp Ile Asp Glu Cys Leu 
    610                 615                 620                 


Asn Pro Ser Thr Cys Pro Asp Glu Gln Cys Val Asn Ser Pro Gly Ser 
625                 630                 635                 640 


Tyr Gln Cys Val Pro Cys Thr Glu Gly Phe Arg Gly Trp Asn Gly Gln 
                645                 650                 655     


Cys Leu Asp Val Asp Glu Cys Leu Glu Pro Asn Val Cys Ala Asn Gly 
            660                 665                 670         


Asp Cys Ser Asn Leu Glu Gly Ser Tyr Met Cys Ser Cys His Lys Gly 
        675                 680                 685             


Tyr Thr Arg Thr Pro Asp His Lys His Cys Arg Asp Ile Asp Glu Cys 
    690                 695                 700                 


Gln Gln Gly Asn Leu Cys Val Asn Gly Gln Cys Lys Asn Thr Glu Gly 
705                 710                 715                 720 


Ser Phe Arg Cys Thr Cys Gly Gln Gly Tyr Gln Leu Ser Ala Ala Lys 
                725                 730                 735     


Asp Gln Cys Glu Asp Ile Asp Glu Cys Gln His Arg His Leu Cys Ala 
            740                 745                 750         


His Gly Gln Cys Arg Asn Thr Glu Gly Ser Phe Gln Cys Val Cys Asp 
        755                 760                 765             


Gln Gly Tyr Arg Ala Ser Gly Leu Gly Asp His Cys Glu Asp Ile Asn 
    770                 775                 780                 


Glu Cys Leu Glu Asp Lys Ser Val Cys Gln Arg Gly Asp Cys Ile Asn 
785                 790                 795                 800 


Thr Ala Gly Ser Tyr Asp Cys Thr Cys Pro Asp Gly Phe Gln Leu Asp 
                805                 810                 815     


Asp Asn Lys Thr Cys Gln Asp Ile Asn Glu Cys Glu His Pro Gly Leu 
            820                 825                 830         


Cys Gly Pro Gln Gly Glu Cys Leu Asn Thr Glu Gly Ser Phe His Cys 
        835                 840                 845             


Val Cys Gln Gln Gly Phe Ser Ile Ser Ala Asp Gly Arg Thr Cys Glu 
    850                 855                 860                 


Asp Ile Asp Glu Cys Val Asn Asn Thr Val Cys Asp Ser His Gly Phe 
865                 870                 875                 880 


Cys Asp Asn Thr Ala Gly Ser Phe Arg Cys Leu Cys Tyr Gln Gly Phe 
                885                 890                 895     


Gln Ala Pro Gln Asp Gly Gln Gly Cys Val Asp Val Asn Glu Cys Glu 
            900                 905                 910         


Leu Leu Ser Gly Val Cys Gly Glu Ala Phe Cys Glu Asn Val Glu Gly 
        915                 920                 925             


Ser Phe Leu Cys Val Cys Ala Asp Glu Asn Gln Glu Tyr Ser Pro Met 
    930                 935                 940                 


Thr Gly Gln Cys Arg Ser Arg Thr Ser Thr Asp Leu Asp Val Asp Val 
945                 950                 955                 960 


Asp Gln Pro Lys Glu Glu Lys Lys Glu Cys Tyr Tyr Asn Leu Asn Asp 
                965                 970                 975     


Ala Ser Leu Cys Asp Asn Val Leu Ala Pro Asn Val Thr Lys Gln Glu 
            980                 985                 990         


Cys Cys Cys Thr Ser Gly Ala Gly  Trp Gly Asp Asn Cys  Glu Ile Phe 
        995                 1000                 1005             


Pro Cys  Pro Val Leu Gly Thr  Ala Glu Phe Thr Glu  Met Cys Pro 
    1010                 1015                 1020             


Lys Gly  Lys Gly Phe Val Pro  Ala Gly Glu Ser Ser  Ser Glu Ala 
    1025                 1030                 1035             


Gly Gly  Glu Asn Tyr Lys Asp  Ala Asp Glu Cys Leu  Leu Phe Gly 
    1040                 1045                 1050             


Gln Glu  Ile Cys Lys Asn Gly  Phe Cys Leu Asn Thr  Arg Pro Gly 
    1055                 1060                 1065             


Tyr Glu  Cys Tyr Cys Lys Gln  Gly Thr Tyr Tyr Asp  Pro Val Lys 
    1070                 1075                 1080             


Leu Gln  Cys Phe Asp Met Asp  Glu Cys Gln Asp Pro  Ser Ser Cys 
    1085                 1090                 1095             


Ile Asp  Gly Gln Cys Val Asn  Thr Glu Gly Ser Tyr  Asn Cys Phe 
    1100                 1105                 1110             


Cys Thr  His Pro Met Val Leu  Asp Ala Ser Glu Lys  Arg Cys Ile 
    1115                 1120                 1125             


Arg Pro  Ala Glu Ser Asn Glu  Gln Ile Glu Glu Thr  Asp Val Tyr 
    1130                 1135                 1140             


Gln Asp  Leu Cys Trp Glu His  Leu Ser Asp Glu Tyr  Val Cys Ser 
    1145                 1150                 1155             


Arg Pro  Leu Val Gly Lys Gln  Thr Thr Tyr Thr Glu  Cys Cys Cys 
    1160                 1165                 1170             


Leu Tyr  Gly Glu Ala Trp Gly  Met Gln Cys Ala Leu  Cys Pro Leu 
    1175                 1180                 1185             


Lys Asp  Ser Asp Asp Tyr Ala  Gln Leu Cys Asn Ile  Pro Val Thr 
    1190                 1195                 1200             


Gly Arg  Arg Gln Pro Tyr Gly  Arg Asp Ala Leu Val  Asp Phe Ser 
    1205                 1210                 1215             


Glu Gln  Tyr Thr Pro Glu Ala  Asp Pro Tyr Phe Ile  Gln Asp Arg 
    1220                 1225                 1230             


Phe Leu  Asn Ser Phe Glu Glu  Leu Gln Ala Glu Glu  Cys Gly Ile 
    1235                 1240                 1245             


Leu Asn  Gly Cys Glu Asn Gly  Arg Cys Val Arg Val  Gln Glu Gly 
    1250                 1255                 1260             


Tyr Thr  Cys Asp Cys Phe Asp  Gly Tyr His Leu Asp  Thr Ala Lys 
    1265                 1270                 1275             


Met Thr  Cys Val Asp Val Asn  Glu Cys Asp Glu Leu  Asn Asn Arg 
    1280                 1285                 1290             


Met Ser  Leu Cys Lys Asn Ala  Lys Cys Ile Asn Thr  Asp Gly Ser 
    1295                 1300                 1305             


Tyr Lys  Cys Leu Cys Leu Pro  Gly Tyr Val Pro Ser  Asp Lys Pro 
    1310                 1315                 1320             


Asn Tyr  Cys Thr Pro Leu Asn  Thr Ala Leu Asn Leu  Glu Lys Asp 
    1325                 1330                 1335             


Ser Asp  Leu Glu 
    1340         


<210>  3978
<211>  1300
<212>  PRT
<213>  homo sapiens

<400>  3978

Met Asp Thr Lys Leu Met Cys Leu Leu Phe Phe Phe Ser Leu Pro Pro 
1               5                   10                  15      


Leu Leu Val Ser Asn His Thr Gly Arg Ile Lys Val Val Phe Thr Pro 
            20                  25                  30          


Ser Ile Cys Lys Val Thr Cys Thr Lys Gly Ser Cys Gln Asn Ser Cys 
        35                  40                  45              


Glu Lys Gly Asn Thr Thr Thr Leu Ile Ser Glu Asn Gly His Ala Ala 
    50                  55                  60                  


Asp Thr Leu Thr Ala Thr Asn Phe Arg Val Val Ile Cys His Leu Pro 
65                  70                  75                  80  


Cys Met Asn Gly Gly Gln Cys Ser Ser Arg Asp Lys Cys Gln Cys Pro 
                85                  90                  95      


Pro Asn Phe Thr Gly Lys Leu Cys Gln Ile Pro Val His Gly Ala Ser 
            100                 105                 110         


Val Pro Lys Leu Tyr Gln His Ser Gln Gln Pro Gly Lys Ala Leu Gly 
        115                 120                 125             


Thr His Val Ile His Ser Thr His Thr Leu Pro Leu Thr Val Thr Ser 
    130                 135                 140                 


Gln Gln Gly Val Lys Val Lys Phe Pro Pro Asn Ile Val Asn Ile His 
145                 150                 155                 160 


Val Lys His Pro Pro Glu Ala Ser Val Gln Ile His Gln Val Ser Arg 
                165                 170                 175     


Ile Asp Gly Pro Thr Gly Gln Lys Thr Lys Glu Ala Gln Pro Gly Gln 
            180                 185                 190         


Ser Gln Val Ser Tyr Gln Gly Leu Pro Val Gln Lys Thr Gln Thr Ile 
        195                 200                 205             


His Ser Thr Tyr Ser His Gln Gln Val Ile Pro His Val Tyr Pro Val 
    210                 215                 220                 


Ala Ala Lys Thr Gln Leu Gly Arg Cys Phe Gln Glu Thr Ile Gly Ser 
225                 230                 235                 240 


Gln Cys Gly Lys Ala Leu Pro Gly Leu Ser Lys Gln Glu Asp Cys Cys 
                245                 250                 255     


Gly Thr Val Gly Thr Ser Trp Gly Phe Asn Lys Cys Gln Lys Cys Pro 
            260                 265                 270         


Lys Lys Pro Ser Tyr His Gly Tyr Asn Gln Met Met Glu Cys Leu Pro 
        275                 280                 285             


Gly Tyr Lys Arg Val Asn Asn Thr Phe Cys Gln Asp Ile Asn Glu Cys 
    290                 295                 300                 


Gln Leu Gln Gly Val Cys Pro Asn Gly Glu Cys Leu Asn Thr Met Gly 
305                 310                 315                 320 


Ser Tyr Arg Cys Thr Cys Lys Ile Gly Phe Gly Pro Asp Pro Thr Phe 
                325                 330                 335     


Ser Ser Cys Val Pro Asp Pro Pro Val Ile Ser Glu Glu Lys Gly Pro 
            340                 345                 350         


Cys Tyr Arg Leu Val Ser Ser Gly Arg Gln Cys Met His Pro Leu Ser 
        355                 360                 365             


Val His Leu Thr Lys Gln Leu Cys Cys Cys Ser Val Gly Lys Ala Trp 
    370                 375                 380                 


Gly Pro His Cys Glu Lys Cys Pro Leu Pro Gly Thr Ala Lys Glu Glu 
385                 390                 395                 400 


Pro Val Glu Ala Leu Thr Phe Ser Arg Glu His Gly Pro Gly Val Ala 
                405                 410                 415     


Glu Pro Glu Val Ala Thr Ala Pro Pro Glu Lys Glu Ile Pro Ser Leu 
            420                 425                 430         


Asp Gln Glu Lys Thr Lys Leu Glu Pro Gly Gln Pro Gln Leu Ser Pro 
        435                 440                 445             


Gly Ile Ser Thr Ile His Leu His Pro Gln Phe Pro Val Val Ile Glu 
    450                 455                 460                 


Lys Thr Ser Pro Pro Val Pro Val Glu Val Ala Pro Glu Ala Ser Thr 
465                 470                 475                 480 


Ser Ser Ala Ser Gln Val Ile Ala Pro Thr Gln Val Thr Glu Ile Asn 
                485                 490                 495     


Glu Cys Thr Val Asn Pro Asp Ile Cys Gly Ala Gly His Cys Ile Asn 
            500                 505                 510         


Leu Pro Val Arg Tyr Thr Cys Ile Cys Tyr Glu Gly Tyr Arg Phe Ser 
        515                 520                 525             


Glu Gln Gln Arg Lys Cys Val Asp Ile Asp Glu Cys Thr Gln Val Gln 
    530                 535                 540                 


His Leu Cys Ser Gln Gly Arg Cys Glu Asn Thr Glu Gly Ser Phe Leu 
545                 550                 555                 560 


Cys Ile Cys Pro Ala Gly Phe Met Ala Ser Glu Glu Gly Thr Asn Cys 
                565                 570                 575     


Ile Asp Val Asp Glu Cys Leu Arg Pro Asp Val Cys Gly Glu Gly His 
            580                 585                 590         


Cys Val Asn Thr Val Gly Ala Phe Arg Cys Glu Tyr Cys Asp Ser Gly 
        595                 600                 605             


Tyr Arg Met Thr Gln Arg Gly Arg Cys Glu Asp Ile Asp Glu Cys Leu 
    610                 615                 620                 


Asn Pro Ser Thr Cys Pro Asp Glu Gln Cys Val Asn Ser Pro Gly Ser 
625                 630                 635                 640 


Tyr Gln Cys Val Pro Cys Thr Glu Gly Phe Arg Gly Trp Asn Gly Gln 
                645                 650                 655     


Cys Leu Asp Val Asp Glu Cys Leu Glu Pro Asn Val Cys Ala Asn Gly 
            660                 665                 670         


Asp Cys Ser Asn Leu Glu Gly Ser Tyr Met Cys Ser Cys His Lys Gly 
        675                 680                 685             


Tyr Thr Arg Thr Pro Asp His Lys His Cys Arg Asp Ile Asp Glu Cys 
    690                 695                 700                 


Gln Gln Gly Asn Leu Cys Val Asn Gly Gln Cys Lys Asn Thr Glu Gly 
705                 710                 715                 720 


Ser Phe Arg Cys Thr Cys Gly Gln Gly Tyr Gln Leu Ser Ala Ala Lys 
                725                 730                 735     


Asp Gln Cys Glu Asp Ile Asp Glu Cys Gln His Arg His Leu Cys Ala 
            740                 745                 750         


His Gly Gln Cys Arg Asn Thr Glu Gly Ser Phe Gln Cys Val Cys Asp 
        755                 760                 765             


Gln Gly Tyr Arg Ala Ser Gly Leu Gly Asp His Cys Glu Asp Ile Asn 
    770                 775                 780                 


Glu Cys Leu Glu Asp Lys Ser Val Cys Gln Arg Gly Asp Cys Ile Asn 
785                 790                 795                 800 


Thr Ala Gly Ser Tyr Asp Cys Thr Cys Pro Asp Gly Phe Gln Leu Asp 
                805                 810                 815     


Asp Asn Lys Thr Cys Gln Asp Ile Asn Glu Cys Glu His Pro Gly Leu 
            820                 825                 830         


Cys Gly Pro Gln Gly Glu Cys Leu Asn Thr Glu Gly Ser Phe His Cys 
        835                 840                 845             


Val Cys Gln Gln Gly Phe Ser Ile Ser Ala Asp Gly Arg Thr Cys Glu 
    850                 855                 860                 


Asp Val Asn Glu Cys Glu Leu Leu Ser Gly Val Cys Gly Glu Ala Phe 
865                 870                 875                 880 


Cys Glu Asn Val Glu Gly Ser Phe Leu Cys Val Cys Ala Asp Glu Asn 
                885                 890                 895     


Gln Glu Tyr Ser Pro Met Thr Gly Gln Cys Arg Ser Arg Thr Ser Thr 
            900                 905                 910         


Asp Leu Asp Val Asp Val Asp Gln Pro Lys Glu Glu Lys Lys Glu Cys 
        915                 920                 925             


Tyr Tyr Asn Leu Asn Asp Ala Ser Leu Cys Asp Asn Val Leu Ala Pro 
    930                 935                 940                 


Asn Val Thr Lys Gln Glu Cys Cys Cys Thr Ser Gly Ala Gly Trp Gly 
945                 950                 955                 960 


Asp Asn Cys Glu Ile Phe Pro Cys Pro Val Leu Gly Thr Ala Glu Phe 
                965                 970                 975     


Thr Glu Met Cys Pro Lys Gly Lys Gly Phe Val Pro Ala Gly Glu Ser 
            980                 985                 990         


Ser Ser Glu Ala Gly Gly Glu Asn  Tyr Lys Asp Ala Asp  Glu Cys Leu 
        995                 1000                 1005             


Leu Phe  Gly Gln Glu Ile Cys  Lys Asn Gly Phe Cys  Leu Asn Thr 
    1010                 1015                 1020             


Arg Pro  Gly Tyr Glu Cys Tyr  Cys Lys Gln Gly Thr  Tyr Tyr Asp 
    1025                 1030                 1035             


Pro Val  Lys Leu Gln Cys Phe  Asp Met Asp Glu Cys  Gln Asp Pro 
    1040                 1045                 1050             


Ser Ser  Cys Ile Asp Gly Gln  Cys Val Asn Thr Glu  Gly Ser Tyr 
    1055                 1060                 1065             


Asn Cys  Phe Cys Thr His Pro  Met Val Leu Asp Ala  Ser Glu Lys 
    1070                 1075                 1080             


Arg Cys  Ile Arg Pro Ala Glu  Ser Asn Glu Gln Ile  Glu Glu Thr 
    1085                 1090                 1095             


Asp Val  Tyr Gln Asp Leu Cys  Trp Glu His Leu Ser  Asp Glu Tyr 
    1100                 1105                 1110             


Val Cys  Ser Arg Pro Leu Val  Gly Lys Gln Thr Thr  Tyr Thr Glu 
    1115                 1120                 1125             


Cys Cys  Cys Leu Tyr Gly Glu  Ala Trp Gly Met Gln  Cys Ala Leu 
    1130                 1135                 1140             


Cys Pro  Leu Lys Asp Ser Asp  Asp Tyr Ala Gln Leu  Cys Asn Ile 
    1145                 1150                 1155             


Pro Val  Thr Gly Arg Arg Gln  Pro Tyr Gly Arg Asp  Ala Leu Val 
    1160                 1165                 1170             


Asp Phe  Ser Glu Gln Tyr Thr  Pro Glu Ala Asp Pro  Tyr Phe Ile 
    1175                 1180                 1185             


Gln Asp  Arg Phe Leu Asn Ser  Phe Glu Glu Leu Gln  Ala Glu Glu 
    1190                 1195                 1200             


Cys Gly  Ile Leu Asn Gly Cys  Glu Asn Gly Arg Cys  Val Arg Val 
    1205                 1210                 1215             


Gln Glu  Gly Tyr Thr Cys Asp  Cys Phe Asp Gly Tyr  His Leu Asp 
    1220                 1225                 1230             


Thr Ala  Lys Met Thr Cys Val  Asp Val Asn Glu Cys  Asp Glu Leu 
    1235                 1240                 1245             


Asn Asn  Arg Met Ser Leu Cys  Lys Asn Ala Lys Cys  Ile Asn Thr 
    1250                 1255                 1260             


Asp Gly  Ser Tyr Lys Cys Leu  Cys Leu Pro Gly Tyr  Val Pro Ser 
    1265                 1270                 1275             


Asp Lys  Pro Asn Tyr Cys Thr  Pro Leu Asn Thr Ala  Leu Asn Leu 
    1280                 1285                 1290             


Glu Lys  Asp Ser Asp Leu Glu  
    1295                 1300 


<210>  3979
<211>  346
<212>  PRT
<213>  homo sapiens

<400>  3979

Met Lys Phe Ser Pro Ala His Tyr Leu Leu Pro Leu Leu Pro Ala Leu 
1               5                   10                  15      


Val Leu Ser Thr Arg Gln Asp Tyr Glu Glu Leu Glu Lys Gln Leu Lys 
            20                  25                  30          


Glu Val Phe Lys Glu Arg Ser Thr Ile Leu Arg Gln Leu Thr Lys Thr 
        35                  40                  45              


Ser Arg Glu Leu Asp Gly Ile Lys Val Asn Leu Gln Ser Leu Lys Asn 
    50                  55                  60                  


Asp Glu Gln Ser Ala Lys Thr Asp Val Gln Lys Leu Leu Glu Leu Gly 
65                  70                  75                  80  


Gln Lys Gln Arg Glu Glu Met Lys Ser Leu Gln Glu Ala Leu Gln Asn 
                85                  90                  95      


Gln Leu Lys Glu Thr Ser Glu Lys Ala Glu Lys His Gln Ala Thr Ile 
            100                 105                 110         


Asn Phe Leu Lys Thr Glu Val Glu Arg Lys Ser Lys Met Ile Arg Asp 
        115                 120                 125             


Leu Gln Asn Glu Asn Lys Ser Leu Lys Asn Lys Leu Leu Ser Gly Asn 
    130                 135                 140                 


Lys Leu Cys Gly Ile His Ala Glu Glu Ser Lys Lys Ile Gln Ala Gln 
145                 150                 155                 160 


Leu Lys Glu Leu Arg Tyr Gly Lys Lys Asp Leu Leu Phe Lys Ala Gln 
                165                 170                 175     


Gln Leu Thr Asp Leu Glu Gln Lys Leu Ala Val Ala Lys Asn Glu Leu 
            180                 185                 190         


Glu Lys Ala Ala Leu Asp Arg Glu Ser Gln Met Lys Ala Met Lys Glu 
        195                 200                 205             


Thr Val Gln Leu Cys Leu Thr Ser Val Phe Arg Asp Gln Pro Pro Pro 
    210                 215                 220                 


Pro Leu Ser Leu Ile Thr Ser Asn Pro Thr Arg Met Leu Leu Pro Pro 
225                 230                 235                 240 


Arg Asn Ile Ala Ser Lys Leu Pro Asp Ala Ala Ala Lys Ser Lys Pro 
                245                 250                 255     


Gln Gln Ser Ala Ser Gly Asn Asn Glu Ser Ser Gln Val Glu Ser Thr 
            260                 265                 270         


Lys Glu Gly Asn Pro Ser Thr Thr Ala Cys Asp Ser Gln Asp Glu Gly 
        275                 280                 285             


Arg Pro Cys Ser Met Lys His Lys Glu Ser Pro Pro Ser Asn Ala Thr 
    290                 295                 300                 


Ala Glu Thr Glu Pro Ile Pro Gln Lys Leu Gln Met Pro Pro Cys Ser 
305                 310                 315                 320 


Glu Cys Glu Val Lys Lys Ala Pro Glu Lys Pro Leu Thr Ser Phe Glu 
                325                 330                 335     


Gly Met Ala Ala Arg Glu Glu Lys Ile Leu 
            340                 345     


<210>  3980
<211>  1214
<212>  PRT
<213>  homo sapiens

<400>  3980

Met Lys Gln Pro Ile Met Ala Asp Gly Pro Arg Cys Lys Arg Arg Lys 
1               5                   10                  15      


Gln Ala Asn Pro Arg Arg Lys Asn Val Val Asn Tyr Asp Asn Val Val 
            20                  25                  30          


Asp Thr Gly Ser Glu Thr Asp Glu Glu Asp Lys Leu His Ile Ala Glu 
        35                  40                  45              


Asp Asp Gly Ile Ala Asn Pro Leu Asp Gln Glu Thr Ser Pro Ala Ser 
    50                  55                  60                  


Val Pro Asn His Glu Ser Ser Pro His Val Ser Gln Ala Leu Leu Pro 
65                  70                  75                  80  


Arg Glu Glu Glu Glu Asp Glu Ile Arg Glu Gly Gly Val Glu His Pro 
                85                  90                  95      


Trp His Asn Asn Glu Ile Leu Gln Ala Ser Val Asp Gly Pro Glu Glu 
            100                 105                 110         


Met Lys Glu Asp Tyr Asp Thr Met Gly Pro Glu Ala Thr Ile Gln Thr 
        115                 120                 125             


Ala Ile Asn Asn Gly Thr Val Lys Asn Ala Asn Cys Thr Ser Asp Phe 
    130                 135                 140                 


Glu Glu Tyr Phe Ala Lys Arg Lys Leu Glu Glu Arg Asp Gly His Ala 
145                 150                 155                 160 


Val Ser Ile Glu Glu Tyr Leu Gln Arg Ser Asp Thr Ala Ile Ile Tyr 
                165                 170                 175     


Pro Glu Ala Pro Glu Glu Leu Ser Arg Leu Gly Thr Pro Glu Ala Asn 
            180                 185                 190         


Gly Gln Glu Glu Asn Asp Leu Pro Pro Gly Thr Pro Asp Ala Phe Ala 
        195                 200                 205             


Gln Leu Leu Thr Cys Pro Tyr Cys Asp Arg Gly Tyr Lys Arg Leu Thr 
    210                 215                 220                 


Ser Leu Lys Glu His Ile Lys Tyr Arg His Glu Lys Asn Glu Glu Asn 
225                 230                 235                 240 


Phe Ser Cys Pro Leu Cys Ser Tyr Thr Phe Ala Tyr Arg Thr Gln Leu 
                245                 250                 255     


Glu Arg His Met Val Thr His Lys Pro Gly Thr Asp Gln His Gln Met 
            260                 265                 270         


Leu Thr Gln Gly Ala Gly Asn Arg Lys Phe Lys Cys Thr Glu Cys Gly 
        275                 280                 285             


Lys Ala Phe Lys Tyr Lys His His Leu Lys Glu His Leu Arg Ile His 
    290                 295                 300                 


Ser Gly Glu Lys Pro Tyr Glu Cys Pro Asn Cys Lys Lys Arg Phe Ser 
305                 310                 315                 320 


His Ser Gly Ser Tyr Ser Ser His Ile Ser Ser Lys Lys Cys Ile Gly 
                325                 330                 335     


Leu Ile Ser Val Asn Gly Arg Met Arg Asn Asn Ile Lys Thr Gly Ser 
            340                 345                 350         


Ser Pro Asn Ser Val Ser Ser Ser Pro Thr Asn Ser Ala Ile Thr Gln 
        355                 360                 365             


Leu Arg Asn Lys Leu Glu Asn Gly Lys Pro Leu Ser Met Ser Glu Gln 
    370                 375                 380                 


Thr Gly Leu Leu Lys Ile Lys Thr Glu Pro Leu Asp Phe Asn Asp Tyr 
385                 390                 395                 400 


Lys Val Leu Met Ala Thr His Gly Phe Ser Gly Thr Ser Pro Phe Met 
                405                 410                 415     


Asn Gly Gly Leu Gly Ala Thr Ser Pro Leu Gly Val His Pro Ser Ala 
            420                 425                 430         


Gln Ser Pro Met Gln His Leu Gly Val Gly Met Glu Ala Pro Leu Leu 
        435                 440                 445             


Gly Phe Pro Thr Met Asn Ser Asn Leu Ser Glu Val Gln Lys Val Leu 
    450                 455                 460                 


Gln Ile Val Asp Asn Thr Val Ser Arg Gln Lys Met Asp Cys Lys Ala 
465                 470                 475                 480 


Glu Glu Ile Ser Lys Leu Lys Gly Tyr His Met Lys Asp Pro Cys Ser 
                485                 490                 495     


Gln Pro Glu Glu Gln Gly Val Thr Ser Pro Asn Ile Pro Pro Val Gly 
            500                 505                 510         


Leu Pro Val Val Ser His Asn Gly Ala Thr Lys Ser Ile Ile Asp Tyr 
        515                 520                 525             


Thr Leu Glu Lys Val Asn Glu Ala Lys Ala Cys Leu Gln Ser Leu Thr 
    530                 535                 540                 


Thr Asp Ser Arg Arg Gln Ile Ser Asn Ile Lys Lys Glu Lys Leu Arg 
545                 550                 555                 560 


Thr Leu Ile Asp Leu Val Thr Asp Asp Lys Met Ile Glu Asn His Asn 
                565                 570                 575     


Ile Ser Thr Pro Phe Ser Cys Gln Phe Cys Lys Glu Ser Phe Pro Gly 
            580                 585                 590         


Pro Ile Pro Leu His Gln His Glu Arg Tyr Leu Cys Lys Met Asn Glu 
        595                 600                 605             


Glu Ile Lys Ala Val Leu Gln Pro His Glu Asn Ile Val Pro Asn Lys 
    610                 615                 620                 


Ala Gly Val Phe Val Asp Asn Lys Ala Leu Leu Leu Ser Ser Val Leu 
625                 630                 635                 640 


Ser Glu Lys Gly Met Thr Ser Pro Ile Asn Pro Tyr Lys Asp His Met 
                645                 650                 655     


Ser Val Leu Lys Ala Tyr Tyr Ala Met Asn Met Glu Pro Asn Ser Asp 
            660                 665                 670         


Glu Leu Leu Lys Ile Ser Ile Ala Val Gly Leu Pro Gln Glu Phe Val 
        675                 680                 685             


Lys Glu Trp Phe Glu Gln Arg Lys Val Tyr Gln Tyr Ser Asn Ser Arg 
    690                 695                 700                 


Ser Pro Ser Leu Glu Arg Ser Ser Lys Pro Leu Ala Pro Asn Ser Asn 
705                 710                 715                 720 


Pro Pro Thr Lys Asp Ser Leu Leu Pro Arg Ser Pro Val Lys Pro Met 
                725                 730                 735     


Asp Ser Ile Thr Ser Pro Ser Ile Ala Glu Leu His Asn Ser Val Thr 
            740                 745                 750         


Asn Cys Asp Pro Pro Leu Arg Leu Thr Lys Pro Ser His Phe Thr Asn 
        755                 760                 765             


Ile Lys Pro Val Glu Lys Leu Asp His Ser Arg Ser Asn Thr Pro Ser 
    770                 775                 780                 


Pro Leu Asn Leu Ser Ser Thr Ser Ser Lys Asn Ser His Ser Ser Ser 
785                 790                 795                 800 


Tyr Thr Pro Asn Ser Phe Ser Ser Glu Glu Leu Gln Ala Glu Pro Leu 
                805                 810                 815     


Asp Leu Ser Leu Pro Lys Gln Met Lys Glu Pro Lys Ser Ile Ile Ala 
            820                 825                 830         


Thr Lys Asn Lys Thr Lys Ala Ser Ser Ile Ser Leu Asp His Asn Ser 
        835                 840                 845             


Val Ser Ser Ser Ser Glu Asn Ser Asp Glu Pro Leu Asn Leu Thr Phe 
    850                 855                 860                 


Ile Lys Lys Glu Phe Ser Asn Ser Asn Asn Leu Asp Asn Lys Ser Thr 
865                 870                 875                 880 


Asn Pro Val Phe Ser Met Asn Pro Phe Ser Ala Lys Pro Leu Tyr Thr 
                885                 890                 895     


Ala Leu Pro Pro Gln Ser Ala Phe Pro Pro Ala Thr Phe Met Pro Pro 
            900                 905                 910         


Val Gln Thr Ser Ile Pro Gly Leu Arg Pro Tyr Pro Gly Leu Asp Gln 
        915                 920                 925             


Met Ser Phe Leu Pro His Met Ala Tyr Thr Tyr Pro Thr Gly Ala Ala 
    930                 935                 940                 


Thr Phe Ala Asp Met Gln Gln Arg Arg Lys Tyr Gln Arg Lys Gln Gly 
945                 950                 955                 960 


Phe Gln Gly Glu Leu Leu Asp Gly Ala Gln Asp Tyr Met Ser Gly Leu 
                965                 970                 975     


Asp Asp Met Thr Asp Ser Asp Ser Cys Leu Ser Arg Lys Lys Ile Lys 
            980                 985                 990         


Lys Thr Glu Ser Gly Met Tyr Ala  Cys Asp Leu Cys Asp  Lys Thr Phe 
        995                 1000                 1005             


Gln Lys  Ser Ser Ser Leu Leu  Arg His Lys Tyr Glu  His Thr Gly 
    1010                 1015                 1020             


Lys Arg  Pro His Gln Cys Gln  Ile Cys Lys Lys Ala  Phe Lys His 
    1025                 1030                 1035             


Lys His  His Leu Ile Glu His  Ser Arg Leu His Ser  Gly Glu Lys 
    1040                 1045                 1050             


Pro Tyr  Gln Cys Asp Lys Cys  Gly Lys Arg Phe Ser  His Ser Gly 
    1055                 1060                 1065             


Ser Tyr  Ser Gln His Met Asn  His Arg Tyr Ser Tyr  Cys Lys Arg 
    1070                 1075                 1080             


Glu Ala  Glu Glu Arg Glu Ala  Ala Glu Arg Glu Ala  Arg Glu Lys 
    1085                 1090                 1095             


Gly His  Leu Glu Pro Thr Glu  Leu Leu Met Asn Arg  Ala Tyr Leu 
    1100                 1105                 1110             


Gln Ser  Ile Thr Pro Gln Gly  Tyr Ser Asp Ser Glu  Glu Arg Glu 
    1115                 1120                 1125             


Ser Met  Pro Arg Asp Gly Glu  Ser Glu Lys Glu His  Glu Lys Glu 
    1130                 1135                 1140             


Gly Glu  Asp Gly Tyr Gly Lys  Leu Gly Arg Gln Asp  Gly Asp Glu 
    1145                 1150                 1155             


Glu Phe  Glu Glu Glu Glu Glu  Glu Ser Glu Asn Lys  Ser Met Asp 
    1160                 1165                 1170             


Thr Asp  Pro Glu Thr Ile Arg  Asp Glu Glu Glu Thr  Gly Asp His 
    1175                 1180                 1185             


Ser Met  Asp Asp Ser Ser Glu  Asp Gly Lys Met Glu  Thr Lys Ser 
    1190                 1195                 1200             


Asp His  Glu Glu Asp Asn Met  Glu Asp Gly Met 
    1205                 1210                 


<210>  3981
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  3981

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Met Gln Asp Leu 
1               5                   10                  15      


Leu Glu Ser Thr Asp Phe Thr Glu His Glu Ile Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Arg Asp Cys Pro Ser Gly His Leu Ser Met Glu Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Gly Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Ala Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Lys Ala Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Glu Lys Ile Phe Arg Gln Met Asp Thr Asn Arg 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Gly Gln 
            180                 185                 190         


Phe 
    


<210>  3982
<211>  182
<212>  PRT
<213>  homo sapiens

<400>  3982

Met Arg Ala Ala Tyr Leu Phe Leu Leu Phe Leu Pro Gly Leu Leu Ala 
1               5                   10                  15      


Gln Gly Gln Tyr Asp Leu Asp Pro Leu Pro Pro Phe Pro Asp His Val 
            20                  25                  30          


Gln Tyr Thr His Tyr Ser Asp Gln Ile Asp Asn Pro Asp Tyr Tyr Asp 
        35                  40                  45              


Tyr Gln Glu Val Thr Pro Arg Pro Ser Glu Glu Gln Phe Gln Phe Gln 
    50                  55                  60                  


Ser Gln Gln Gln Val Gln Gln Glu Val Ile Pro Ala Pro Thr Pro Glu 
65                  70                  75                  80  


Pro Gly Asn Ala Glu Leu Glu Pro Thr Glu Pro Gly Pro Leu Asp Cys 
                85                  90                  95      


Arg Glu Glu Gln Tyr Pro Cys Thr Arg Leu Tyr Ser Ile His Arg Pro 
            100                 105                 110         


Cys Lys Gln Cys Leu Asn Glu Val Cys Phe Tyr Ser Leu Arg Arg Val 
        115                 120                 125             


Tyr Val Ile Asn Lys Glu Ile Cys Val Arg Thr Val Cys Ala His Glu 
    130                 135                 140                 


Glu Leu Leu Arg Ala Asp Leu Cys Arg Asp Lys Phe Ser Lys Cys Gly 
145                 150                 155                 160 


Val Met Ala Ser Ser Gly Leu Cys Gln Ser Val Ala Ala Ser Cys Ala 
                165                 170                 175     


Arg Ser Cys Gly Ser Cys 
            180         


<210>  3983
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  3983

Met Ala Gln Ala Ser Leu Leu Ala Cys Glu Gly Leu Ala Gly Val Ser 
1               5                   10                  15      


Leu Val Pro Thr Ala Ala Ser Lys Lys Met Met Leu Ser Gln Ile Ala 
            20                  25                  30          


Ser Lys Gln Ala Glu Asn Gly Glu Arg Ala Gly Ser Pro Asp Val Leu 
        35                  40                  45              


Arg Cys Ser Ser Gln Gly His Arg Lys Asp Ser Asp Lys Ser Arg Ser 
    50                  55                  60                  


Arg Lys Asp Asp Asp Ser Leu Ser Glu Ala Ser His Ser Lys Lys Thr 
65                  70                  75                  80  


Val Lys Lys Val Val Val Val Glu Gln Asn Gly Ser Phe Gln Val Lys 
                85                  90                  95      


Ile Pro Lys Asn Phe Val Cys Glu His Cys Phe Gly Ala Phe Arg Ser 
            100                 105                 110         


Ser Tyr His Leu Lys Arg His Ile Leu Ile His Thr Gly Glu Lys Pro 
        115                 120                 125             


Phe Glu Cys Asp Ile Cys Asp Met Arg Phe Ile Gln Lys Tyr His Leu 
    130                 135                 140                 


Glu Arg His Lys Arg Val His Ser Gly Glu Lys Pro Tyr Gln Cys Glu 
145                 150                 155                 160 


Arg Cys His Gln Cys Phe Ser Arg Thr Asp Arg Leu Leu Arg His Lys 
                165                 170                 175     


Arg Met Cys Gln Gly Cys Gln Ser Lys Thr Ser Asp Gly Gln Phe Ser 
            180                 185                 190         


Leu 
    


<210>  3984
<211>  530
<212>  PRT
<213>  homo sapiens

<400>  3984

Met Ala Thr Pro Asp Val Ser Val His Met Glu Glu Val Val Val Val 
1               5                   10                  15      


Thr Thr Pro Asp Thr Ala Val Asp Gly Ser Gly Val Glu Gly Val Lys 
            20                  25                  30          


Thr Val Leu Val Thr Thr Asn Leu Ala Pro His Gly Gly Asp Leu Thr 
        35                  40                  45              


Glu Asp Asn Met Glu Thr Glu Asn Ala Ala Ala Ala Ala Ala Ala Ala 
    50                  55                  60                  


Phe Thr Ala Ser Ser Gln Leu Lys Glu Ala Val Leu Val Lys Met Ala 
65                  70                  75                  80  


Glu Glu Gly Glu Asn Leu Glu Ala Glu Ile Val Tyr Pro Ile Thr Cys 
                85                  90                  95      


Gly Asp Ser Arg Ala Asn Leu Ile Trp Arg Lys Phe Val Cys Pro Gly 
            100                 105                 110         


Ile Asn Val Lys Cys Val Gln Tyr Asp Glu His Val Ile Ser Pro Lys 
        115                 120                 125             


Glu Phe Val His Leu Ala Gly Lys Ser Thr Leu Lys Asp Trp Lys Arg 
    130                 135                 140                 


Ala Ile Arg Met Asn Gly Ile Met Leu Arg Lys Ile Met Asp Ser Gly 
145                 150                 155                 160 


Glu Leu Asp Phe Tyr Gln His Asp Lys Val Cys Ser Asn Thr Cys Arg 
                165                 170                 175     


Ser Thr Lys Ile Asp Leu Ser Gly Ala Arg Val Ser Leu Ser Ser Pro 
            180                 185                 190         


Thr Ser Ala Glu Tyr Ile Pro Leu Thr Pro Ala Ala Ala Asp Val Asn 
        195                 200                 205             


Gly Ser Pro Ala Thr Ile Thr Ile Glu Thr Cys Glu Asp Pro Gly Asp 
    210                 215                 220                 


Trp Thr Ala Ala Ile Gly Asp Asp Thr Phe Thr Phe Trp Arg Gly Leu 
225                 230                 235                 240 


Lys Asp Ala Gly Leu Leu Asp Glu Val Ile Gln Glu Phe His Gln Glu 
                245                 250                 255     


Leu Val Glu Thr Met Arg Gly Leu Gln Gln Arg Val Gln Asp Pro Pro 
            260                 265                 270         


Leu Gln Leu Arg Asp Ala Val Leu Leu Asn Asn Ile Val Gln Asn Phe 
        275                 280                 285             


Gly Met Leu Asp Leu Val Lys Lys Val Leu Ala Ser His Lys Cys Gln 
    290                 295                 300                 


Met Asp Arg Ser Arg Glu Gln Tyr Ala Arg Asp Leu Ala Ala Leu Glu 
305                 310                 315                 320 


Gln Gln Cys Asp Glu His Arg Arg Arg Ala Lys Glu Leu Lys His Lys 
                325                 330                 335     


Ser Gln His Leu Ser Asn Val Leu Met Thr Leu Thr Pro Val Ser Leu 
            340                 345                 350         


Pro Pro Pro Val Lys Arg Pro Arg Leu Ala Arg Ala Thr Ser Gly Pro 
        355                 360                 365             


Ala Ala Met Ala Ser Gln Val Leu Thr Gln Ser Ala Gln Leu Ala Leu 
    370                 375                 380                 


Gly Pro Gly Val Pro Val Pro Gln Leu Thr Ser Val Pro Leu Gly Lys 
385                 390                 395                 400 


Val Val Ser Thr Leu Pro Ser Thr Val Leu Gly Lys Gly Ser Leu Gln 
                405                 410                 415     


Ala Pro Pro Ala Ser Ser Pro Ala Ser Pro Leu Leu Gly Gly Tyr Thr 
            420                 425                 430         


Val Leu Ala Ser Ser Gly Ser Thr Tyr Pro Ser Thr Val Glu Ile His 
        435                 440                 445             


Pro Asp Ala Ser Ser Leu Thr Val Leu Ser Thr Ala Ala Val Gln Asp 
    450                 455                 460                 


Gly Ser Thr Val Phe Lys Val Val Ser Pro Leu Gln Leu Leu Thr Leu 
465                 470                 475                 480 


Pro Gly Leu Gly Pro Thr Leu Gln Asn Val Ala Gln Ala Ser Pro Gly 
                485                 490                 495     


Ser Ser Thr Ile Val Thr Val Pro Ala Gly Ala Ala Pro Gly Pro Glu 
            500                 505                 510         


Glu His Thr Ala Thr Ile Glu Val Ala Ala Met Ala Glu Asp His Glu 
        515                 520                 525             


Arg Lys 
    530 


<210>  3985
<211>  333
<212>  PRT
<213>  homo sapiens

<400>  3985

Met Ala Val Arg Arg Asp Ser Val Trp Lys Tyr Cys Trp Gly Val Leu 
1               5                   10                  15      


Met Val Leu Cys Arg Thr Ala Ile Ser Lys Ser Ile Val Leu Glu Pro 
            20                  25                  30          


Ile Tyr Trp Asn Ser Ser Asn Ser Lys Phe Leu Pro Gly Gln Gly Leu 
        35                  40                  45              


Val Leu Tyr Pro Gln Ile Gly Asp Lys Leu Asp Ile Ile Cys Pro Lys 
    50                  55                  60                  


Val Asp Ser Lys Thr Val Gly Gln Tyr Glu Tyr Tyr Lys Val Tyr Met 
65                  70                  75                  80  


Val Asp Lys Asp Gln Ala Asp Arg Cys Thr Ile Lys Lys Glu Asn Thr 
                85                  90                  95      


Pro Leu Leu Asn Cys Ala Lys Pro Asp Gln Asp Ile Lys Phe Thr Ile 
            100                 105                 110         


Lys Phe Gln Glu Phe Ser Pro Asn Leu Trp Gly Leu Glu Phe Gln Lys 
        115                 120                 125             


Asn Lys Asp Tyr Tyr Ile Ile Ser Thr Ser Asn Gly Ser Leu Glu Gly 
    130                 135                 140                 


Leu Asp Asn Gln Glu Gly Gly Val Cys Gln Thr Arg Ala Met Lys Ile 
145                 150                 155                 160 


Leu Met Lys Val Gly Gln Asp Ala Ser Ser Ala Gly Ser Thr Arg Asn 
                165                 170                 175     


Lys Asp Pro Thr Arg Arg Pro Glu Leu Glu Ala Gly Thr Asn Gly Arg 
            180                 185                 190         


Ser Ser Thr Thr Ser Pro Phe Val Lys Pro Asn Pro Gly Ser Ser Thr 
        195                 200                 205             


Asp Gly Asn Ser Ala Gly His Ser Gly Asn Asn Ile Leu Gly Ser Glu 
    210                 215                 220                 


Val Ala Leu Phe Ala Gly Ile Ala Ser Gly Cys Ile Ile Phe Ile Val 
225                 230                 235                 240 


Ile Ile Ile Thr Leu Val Val Leu Leu Leu Lys Tyr Arg Arg Arg His 
                245                 250                 255     


Arg Lys His Ser Pro Gln His Thr Thr Thr Leu Ser Leu Ser Thr Leu 
            260                 265                 270         


Ala Thr Pro Lys Arg Ser Gly Asn Asn Asn Gly Ser Glu Pro Ser Asp 
        275                 280                 285             


Ile Ile Ile Pro Leu Arg Thr Ala Asp Ser Val Phe Cys Pro His Tyr 
    290                 295                 300                 


Glu Lys Val Ser Gly Asp Tyr Gly His Pro Val Tyr Ile Val Gln Glu 
305                 310                 315                 320 


Met Pro Pro Gln Ser Pro Ala Asn Ile Tyr Tyr Lys Val 
                325                 330             


<210>  3986
<211>  508
<212>  PRT
<213>  homo sapiens

<400>  3986

Met Ile Tyr Glu Glu Ser Lys Met Asn Leu Glu Gln Glu Arg Pro Phe 
1               5                   10                  15      


Val Cys Ser Ala Pro Gly Cys Ser Gln Arg Phe Pro Thr Glu Asp His 
            20                  25                  30          


Leu Met Ile His Arg His Lys His Glu Met Thr Leu Lys Phe Pro Ser 
        35                  40                  45              


Ile Lys Thr Asp Asn Met Leu Ser Asp Gln Thr Pro Thr Pro Thr Arg 
    50                  55                  60                  


Phe Leu Lys Asn Cys Glu Glu Val Gly Leu Phe Ser Glu Leu Asp Cys 
65                  70                  75                  80  


Ser Leu Glu His Glu Phe Arg Lys Ala Gln Glu Glu Glu Ser Ser Lys 
                85                  90                  95      


Arg Asn Ile Ser Met His Asn Ala Val Gly Gly Ala Met Thr Gly Pro 
            100                 105                 110         


Gly Thr His Gln Leu Ser Ser Ala Arg Leu Pro Asn His Asp Thr Asn 
        115                 120                 125             


Val Val Ile Gln Gln Ala Met Pro Ser Pro Gln Ser Ser Ser Val Ile 
    130                 135                 140                 


Thr Gln Ala Pro Ser Thr Asn Arg Gln Ile Gly Pro Val Pro Gly Ser 
145                 150                 155                 160 


Leu Ser Ser Leu Leu His Leu His Asn Arg Gln Arg Gln Pro Met Pro 
                165                 170                 175     


Ala Ser Met Pro Gly Thr Leu Pro Asn Pro Thr Met Pro Gly Ser Ser 
            180                 185                 190         


Ala Val Leu Met Pro Met Glu Arg Gln Met Ser Val Asn Ser Ser Ile 
        195                 200                 205             


Met Gly Met Gln Gly Pro Asn Leu Ser Asn Pro Cys Ala Ser Pro Gln 
    210                 215                 220                 


Val Gln Pro Met His Ser Glu Ala Lys Met Arg Leu Lys Ala Ala Leu 
225                 230                 235                 240 


Thr His His Pro Ala Ala Met Ser Asn Gly Asn Met Asn Thr Met Gly 
                245                 250                 255     


His Met Met Glu Met Met Gly Ser Arg Gln Asp Gln Thr Pro His His 
            260                 265                 270         


His Met His Ser His Pro His Gln His Gln Thr Leu Pro Pro His His 
        275                 280                 285             


Pro Tyr Pro His Gln His Gln His Pro Ala His His Pro His Pro Gln 
    290                 295                 300                 


Pro His His Gln Gln Asn His Pro His His His Ser His Ser His Leu 
305                 310                 315                 320 


His Ala His Pro Ala His His Gln Thr Ser Pro His Pro Pro Leu His 
                325                 330                 335     


Thr Gly Asn Gln Ala Gln Val Ser Pro Ala Thr Gln Gln Met Gln Pro 
            340                 345                 350         


Thr Gln Thr Ile Gln Pro Pro Gln Pro Thr Gly Gly Arg Arg Arg Arg 
        355                 360                 365             


Val Val Asp Glu Asp Pro Asp Glu Arg Arg Arg Lys Phe Leu Glu Arg 
    370                 375                 380                 


Asn Arg Ala Ala Ala Thr Arg Cys Arg Gln Lys Arg Lys Val Trp Val 
385                 390                 395                 400 


Met Ser Leu Glu Lys Lys Ala Glu Glu Leu Thr Gln Thr Asn Met Gln 
                405                 410                 415     


Leu Gln Asn Glu Val Ser Met Leu Lys Asn Glu Val Ala Gln Leu Lys 
            420                 425                 430         


Gln Leu Leu Leu Thr His Lys Asp Cys Pro Ile Thr Ala Met Gln Lys 
        435                 440                 445             


Glu Ser Gln Gly Tyr Leu Ser Pro Glu Ser Ser Pro Pro Ala Ser Pro 
    450                 455                 460                 


Val Pro Ala Cys Ser Gln Gln Gln Val Ile Gln His Asn Thr Ile Thr 
465                 470                 475                 480 


Thr Ser Ser Ser Val Ser Glu Val Val Gly Ser Ser Thr Leu Ser Gln 
                485                 490                 495     


Leu Thr Thr His Arg Thr Asp Leu Asn Pro Ile Leu 
            500                 505             


<210>  3987
<211>  2363
<212>  PRT
<213>  homo sapiens

<400>  3987

Met Pro Val Leu Gly Val Ala Ser Lys Leu Arg Gln Pro Ala Val Gly 
1               5                   10                  15      


Ser Lys Pro Val His Thr Ala Leu Pro Ile Pro Asn Leu Gly Thr Thr 
            20                  25                  30          


Gly Ser Gln His Cys Ser Ser Arg Pro Leu Glu Leu Thr Glu Thr Glu 
        35                  40                  45              


Ser Ser Met Leu Ser Cys Gln Leu Ala Leu Lys Ser Thr Cys Glu Phe 
    50                  55                  60                  


Gly Glu Lys Lys Pro Leu Gln Gly Lys Ala Lys Glu Lys Glu Asp Ser 
65                  70                  75                  80  


Lys Ile Tyr Thr Asp Trp Ala Asn His Tyr Leu Ala Lys Ser Gly His 
                85                  90                  95      


Lys Arg Leu Ile Lys Asp Leu Gln Gln Asp Ile Ala Asp Gly Val Leu 
            100                 105                 110         


Leu Ala Glu Ile Ile Gln Ile Ile Ala Asn Glu Lys Val Glu Asp Ile 
        115                 120                 125             


Asn Gly Cys Pro Arg Ser Gln Ser Gln Met Ile Glu Asn Val Asp Val 
    130                 135                 140                 


Cys Leu Ser Phe Leu Ala Ala Arg Gly Val Asn Val Gln Gly Leu Ser 
145                 150                 155                 160 


Ala Glu Glu Ile Arg Asn Gly Asn Leu Lys Ala Ile Leu Gly Leu Phe 
                165                 170                 175     


Phe Ser Leu Ser Arg Tyr Lys Gln Gln Gln His His Gln Gln Gln Tyr 
            180                 185                 190         


Tyr Gln Ser Leu Val Glu Leu Gln Gln Arg Val Thr His Ala Ser Pro 
        195                 200                 205             


Pro Ser Glu Ala Ser Gln Ala Lys Thr Gln Gln Asp Met Gln Ser Ser 
    210                 215                 220                 


Leu Ala Ala Arg Tyr Ala Thr Gln Ser Asn His Ser Gly Ile Ala Thr 
225                 230                 235                 240 


Ser Gln Lys Lys Pro Thr Arg Leu Pro Gly Pro Ser Arg Val Pro Ala 
                245                 250                 255     


Ala Gly Ser Ser Ser Lys Val Gln Gly Ala Ser Asn Leu Asn Arg Arg 
            260                 265                 270         


Ser Gln Ser Phe Asn Ser Ile Asp Lys Asn Lys Pro Pro Asn Tyr Ala 
        275                 280                 285             


Asn Gly Asn Glu Lys Asp Ser Ser Lys Gly Pro Gln Ser Ser Ser Gly 
    290                 295                 300                 


Val Asn Gly Asn Val Gln Pro Pro Ser Thr Ala Gly Gln Pro Pro Ala 
305                 310                 315                 320 


Ser Ala Ile Pro Ser Pro Ser Ala Ser Lys Pro Trp Arg Ser Lys Ser 
                325                 330                 335     


Met Asn Val Lys His Ser Ala Thr Ser Thr Met Leu Thr Val Lys Gln 
            340                 345                 350         


Ser Ser Thr Ala Thr Ser Pro Thr Pro Ser Ser Asp Arg Leu Lys Pro 
        355                 360                 365             


Pro Val Ser Glu Gly Val Lys Thr Ala Pro Ser Gly Gln Lys Ser Met 
    370                 375                 380                 


Leu Glu Lys Phe Lys Leu Val Asn Ala Arg Thr Ala Leu Arg Pro Pro 
385                 390                 395                 400 


Gln Pro Pro Ser Ser Gly Pro Ser Asp Gly Gly Lys Asp Asp Asp Ala 
                405                 410                 415     


Phe Ser Glu Ser Gly Glu Met Glu Gly Phe Asn Ser Gly Leu Asn Ser 
            420                 425                 430         


Gly Gly Ser Thr Asn Ser Ser Pro Lys Val Ser Pro Lys Leu Ala Pro 
        435                 440                 445             


Pro Lys Ala Gly Ser Lys Asn Leu Ser Asn Lys Lys Ser Leu Leu Gln 
    450                 455                 460                 


Pro Lys Glu Lys Glu Glu Lys Asn Arg Asp Lys Asn Lys Val Cys Thr 
465                 470                 475                 480 


Glu Lys Pro Val Lys Glu Glu Lys Asp Gln Val Thr Glu Met Ala Pro 
                485                 490                 495     


Lys Lys Thr Ser Lys Ile Ala Ser Leu Ile Pro Lys Gly Ser Lys Thr 
            500                 505                 510         


Thr Ala Ala Lys Lys Glu Ser Leu Ile Pro Ser Ser Ser Gly Ile Pro 
        515                 520                 525             


Lys Pro Gly Ser Lys Val Pro Thr Val Lys Gln Thr Ile Ser Pro Gly 
    530                 535                 540                 


Ser Thr Ala Ser Lys Glu Ser Glu Lys Phe Arg Thr Thr Lys Gly Ser 
545                 550                 555                 560 


Pro Ser Gln Ser Leu Ser Lys Pro Ile Thr Met Glu Lys Ala Ser Ala 
                565                 570                 575     


Ser Ser Cys Pro Ala Pro Leu Glu Gly Arg Glu Ala Gly Gln Ala Ser 
            580                 585                 590         


Pro Ser Gly Ser Cys Thr Met Thr Val Ala Gln Ser Ser Gly Gln Ser 
        595                 600                 605             


Thr Gly Asn Gly Ala Val Gln Leu Pro Gln Gln Gln Gln His Ser His 
    610                 615                 620                 


Pro Asn Thr Ala Thr Val Ala Pro Phe Ile Tyr Arg Ala His Ser Glu 
625                 630                 635                 640 


Asn Glu Gly Thr Ala Leu Pro Ser Ala Asp Ser Cys Thr Ser Pro Thr 
                645                 650                 655     


Lys Met Asp Leu Ser Tyr Ser Lys Thr Ala Lys Gln Cys Leu Glu Glu 
            660                 665                 670         


Ile Ser Gly Glu Asp Pro Glu Thr Arg Arg Met Arg Thr Val Lys Asn 
        675                 680                 685             


Ile Ala Asp Leu Arg Gln Asn Leu Glu Glu Thr Met Ser Ser Leu Arg 
    690                 695                 700                 


Gly Thr Gln Ile Ser His Ser Thr Leu Glu Thr Thr Phe Asp Ser Thr 
705                 710                 715                 720 


Val Thr Thr Glu Val Asn Gly Arg Thr Ile Pro Asn Leu Thr Ser Arg 
                725                 730                 735     


Pro Thr Pro Met Thr Trp Arg Leu Gly Gln Ala Cys Pro Arg Leu Gln 
            740                 745                 750         


Ala Gly Asp Ala Pro Ser Leu Gly Ala Gly Tyr Pro Arg Ser Gly Thr 
        755                 760                 765             


Ser Arg Phe Ile His Thr Asp Pro Ser Arg Phe Met Tyr Thr Thr Pro 
    770                 775                 780                 


Leu Arg Arg Ala Ala Val Ser Arg Leu Gly Asn Met Ser Gln Ile Asp 
785                 790                 795                 800 


Met Ser Glu Lys Ala Ser Ser Asp Leu Asp Met Ser Ser Glu Val Asp 
                805                 810                 815     


Val Gly Gly Tyr Met Ser Asp Gly Asp Ile Leu Gly Lys Ser Leu Arg 
            820                 825                 830         


Thr Asp Asp Ile Asn Ser Gly Tyr Met Thr Asp Gly Gly Leu Asn Leu 
        835                 840                 845             


Tyr Thr Arg Ser Leu Asn Arg Ile Pro Asp Thr Ala Thr Ser Arg Asp 
    850                 855                 860                 


Ile Ile Gln Arg Gly Val His Asp Val Thr Val Asp Ala Asp Ser Trp 
865                 870                 875                 880 


Asp Asp Ser Ser Ser Val Ser Ser Gly Leu Ser Asp Thr Leu Asp Asn 
                885                 890                 895     


Ile Ser Thr Asp Asp Leu Asn Thr Thr Ser Ser Val Ser Ser Tyr Ser 
            900                 905                 910         


Asn Ile Thr Val Pro Ser Arg Lys Asn Thr Gln Leu Arg Thr Asp Ser 
        915                 920                 925             


Glu Lys Arg Ser Thr Thr Asp Glu Thr Trp Asp Ser Pro Glu Glu Leu 
    930                 935                 940                 


Lys Lys Pro Glu Glu Asp Phe Asp Ser His Gly Asp Ala Gly Gly Lys 
945                 950                 955                 960 


Trp Lys Thr Val Ser Ser Gly Leu Pro Glu Asp Pro Glu Lys Ala Gly 
                965                 970                 975     


Gln Lys Ala Ser Leu Ser Val Ser Gln Thr Gly Ser Trp Arg Arg Gly 
            980                 985                 990         


Met Ser Ala Gln Gly Gly Ala Pro  Ser Arg Gln Lys Ala  Gly Thr Ser 
        995                 1000                 1005             


Ala Leu  Lys Thr Pro Gly Lys  Thr Asp Asp Ala Lys  Ala Ser Glu 
    1010                 1015                 1020             


Lys Gly  Lys Ala Pro Leu Lys  Gly Ser Ser Leu Gln  Arg Ser Pro 
    1025                 1030                 1035             


Ser Asp  Ala Gly Lys Ser Ser  Gly Asp Glu Gly Lys  Lys Pro Pro 
    1040                 1045                 1050             


Ser Gly  Ile Gly Arg Ser Thr  Ala Thr Ser Ser Phe  Gly Phe Lys 
    1055                 1060                 1065             


Lys Pro  Ser Gly Val Gly Ser  Ser Ala Met Ile Thr  Ser Ser Gly 
    1070                 1075                 1080             


Ala Thr  Ile Thr Ser Gly Ser  Ala Thr Leu Gly Lys  Ile Pro Lys 
    1085                 1090                 1095             


Ser Ala  Ala Ile Gly Gly Lys  Ser Asn Ala Gly Arg  Lys Thr Ser 
    1100                 1105                 1110             


Leu Asp  Gly Ser Gln Asn Gln  Asp Asp Val Val Leu  His Val Ser 
    1115                 1120                 1125             


Ser Lys  Thr Thr Leu Gln Tyr  Arg Ser Leu Pro Arg  Pro Ser Lys 
    1130                 1135                 1140             


Ser Ser  Thr Ser Gly Ile Pro  Gly Arg Gly Gly His  Arg Ser Ser 
    1145                 1150                 1155             


Thr Ser  Ser Ile Asp Ser Asn  Val Ser Ser Lys Ser  Ala Gly Ala 
    1160                 1165                 1170             


Thr Thr  Ser Lys Leu Arg Glu  Pro Thr Lys Ile Gly  Ser Gly Arg 
    1175                 1180                 1185             


Ser Ser  Pro Val Thr Val Asn  Gln Thr Asp Lys Glu  Lys Glu Lys 
    1190                 1195                 1200             


Val Ala  Val Ser Asp Ser Glu  Ser Val Ser Leu Ser  Gly Ser Pro 
    1205                 1210                 1215             


Lys Ser  Ser Pro Thr Ser Ala  Ser Ala Cys Gly Ala  Gln Gly Leu 
    1220                 1225                 1230             


Arg Gln  Pro Gly Ser Lys Tyr  Pro Asp Ile Ala Ser  Pro Thr Phe 
    1235                 1240                 1245             


Arg Arg  Leu Phe Gly Ala Lys  Ala Gly Gly Lys Ser  Ala Ser Ala 
    1250                 1255                 1260             


Pro Asn  Thr Glu Gly Val Lys  Ser Ser Ser Val Met  Pro Ser Pro 
    1265                 1270                 1275             


Ser Thr  Thr Leu Ala Arg Gln  Gly Ser Leu Glu Ser  Pro Ser Ser 
    1280                 1285                 1290             


Gly Thr  Gly Ser Met Gly Ser  Ala Gly Gly Leu Ser  Gly Ser Ser 
    1295                 1300                 1305             


Ser Pro  Leu Phe Asn Lys Pro  Ser Asp Leu Thr Thr  Asp Val Ile 
    1310                 1315                 1320             


Ser Leu  Ser His Ser Leu Ala  Ser Ser Pro Ala Ser  Val His Ser 
    1325                 1330                 1335             


Phe Thr  Ser Gly Gly Leu Val  Trp Ala Ala Asn Met  Ser Ser Ser 
    1340                 1345                 1350             


Ser Ala  Gly Ser Lys Asp Thr  Pro Ser Tyr Gln Ser  Met Thr Ser 
    1355                 1360                 1365             


Leu His  Thr Ser Ser Glu Ser  Ile Asp Leu Pro Leu  Ser His His 
    1370                 1375                 1380             


Gly Ser  Leu Ser Gly Leu Thr  Thr Gly Thr His Glu  Val Gln Ser 
    1385                 1390                 1395             


Leu Leu  Met Arg Thr Gly Ser  Val Arg Ser Thr Leu  Ser Glu Ser 
    1400                 1405                 1410             


Met Gln  Leu Asp Arg Asn Thr  Leu Pro Lys Lys Gly  Leu Arg Tyr 
    1415                 1420                 1425             


Thr Pro  Ser Ser Arg Gln Ala  Asn Gln Glu Glu Gly  Lys Glu Trp 
    1430                 1435                 1440             


Leu Arg  Ser His Ser Thr Gly  Gly Leu Gln Asp Thr  Gly Asn Gln 
    1445                 1450                 1455             


Ser Pro  Leu Val Ser Pro Ser  Ala Met Ser Ser Ser  Ala Ala Gly 
    1460                 1465                 1470             


Lys Tyr  His Phe Ser Asn Leu  Val Ser Pro Thr Asn  Leu Ser Gln 
    1475                 1480                 1485             


Phe Asn  Leu Pro Gly Pro Ser  Met Met Arg Ser Asn  Ser Ile Pro 
    1490                 1495                 1500             


Ala Gln  Asp Ser Ser Phe Asp  Leu Tyr Asp Asp Ser  Gln Leu Cys 
    1505                 1510                 1515             


Gly Ser  Ala Thr Ser Leu Glu  Glu Arg Pro Arg Ala  Ile Ser His 
    1520                 1525                 1530             


Ser Gly  Ser Phe Arg Asp Ser  Met Glu Glu Val His  Gly Ser Ser 
    1535                 1540                 1545             


Leu Ser  Leu Val Ser Ser Thr  Ser Ser Leu Tyr Ser  Thr Ala Glu 
    1550                 1555                 1560             


Glu Lys  Ala His Ser Glu Gln  Ile His Lys Leu Arg  Arg Glu Leu 
    1565                 1570                 1575             


Val Ala  Ser Gln Glu Lys Val  Ala Thr Leu Thr Ser  Gln Leu Ser 
    1580                 1585                 1590             


Ala Asn  Ala His Leu Val Ala  Ala Phe Glu Lys Ser  Leu Gly Asn 
    1595                 1600                 1605             


Met Thr  Gly Arg Leu Gln Ser  Leu Thr Met Thr Ala  Glu Gln Lys 
    1610                 1615                 1620             


Glu Ser  Glu Leu Ile Glu Leu  Arg Glu Thr Ile Glu  Met Leu Lys 
    1625                 1630                 1635             


Ala Gln  Asn Ser Ala Ala Gln  Ala Ala Ile Gln Gly  Ala Leu Asn 
    1640                 1645                 1650             


Gly Pro  Asp His Pro Pro Lys  Asp Leu Arg Ile Arg  Arg Gln His 
    1655                 1660                 1665             


Ser Ser  Glu Ser Val Ser Ser  Ile Asn Ser Ala Thr  Ser His Ser 
    1670                 1675                 1680             


Ser Ile  Gly Ser Gly Asn Asp  Ala Asp Ser Lys Lys  Lys Lys Lys 
    1685                 1690                 1695             


Lys Asn  Trp Val Asn Ser Arg  Gly Ser Glu Leu Arg  Ser Ser Phe 
    1700                 1705                 1710             


Lys Gln  Ala Phe Gly Lys Lys  Lys Ser Thr Lys Pro  Pro Ser Ser 
    1715                 1720                 1725             


His Ser  Asp Ile Glu Glu Leu  Thr Asp Ser Ser Leu  Pro Ala Ser 
    1730                 1735                 1740             


Pro Lys  Leu Pro His Asn Ala  Gly Asp Cys Gly Ser  Ala Ser Met 
    1745                 1750                 1755             


Lys Pro  Ser Gln Ser Ala Ser  Ala Ile Cys Glu Cys  Thr Glu Ala 
    1760                 1765                 1770             


Glu Ala  Glu Ile Ile Leu Gln  Leu Lys Ser Glu Leu  Arg Glu Lys 
    1775                 1780                 1785             


Glu Leu  Lys Leu Thr Asp Ile  Arg Leu Glu Ala Leu  Ser Ser Ala 
    1790                 1795                 1800             


His His  Leu Asp Gln Ile Arg  Glu Ala Met Asn Arg  Met Gln Asn 
    1805                 1810                 1815             


Glu Ile  Glu Ile Leu Lys Ala  Glu Asn Asp Arg Leu  Lys Ala Glu 
    1820                 1825                 1830             


Thr Gly  Asn Thr Ala Lys Pro  Thr Arg Pro Pro Ser  Glu Ser Ser 
    1835                 1840                 1845             


Ser Ser  Thr Ser Ser Ser Ser  Ser Arg Gln Ser Leu  Gly Leu Ser 
    1850                 1855                 1860             


Leu Asn  Asn Leu Asn Ile Thr  Glu Ala Val Ser Ser  Asp Ile Leu 
    1865                 1870                 1875             


Leu Asp  Asp Ala Gly Asp Ala  Thr Gly His Lys Asp  Gly Arg Ser 
    1880                 1885                 1890             


Val Lys  Ile Ile Val Ser Ile  Ser Lys Gly Tyr Gly  Arg Ala Lys 
    1895                 1900                 1905             


Asp Gln  Lys Ser Gln Ala Tyr  Leu Ile Gly Ser Ile  Gly Val Ser 
    1910                 1915                 1920             


Gly Lys  Thr Lys Trp Asp Val  Leu Asp Gly Val Ile  Arg Arg Leu 
    1925                 1930                 1935             


Phe Lys  Glu Tyr Val Phe Arg  Ile Asp Thr Ser Thr  Ser Leu Gly 
    1940                 1945                 1950             


Leu Ser  Ser Asp Cys Ile Ala  Ser Tyr Cys Ile Gly  Asp Leu Ile 
    1955                 1960                 1965             


Arg Ser  His Asn Leu Glu Val  Pro Glu Leu Leu Pro  Cys Gly Tyr 
    1970                 1975                 1980             


Leu Val  Gly Asp Asn Asn Ile  Ile Thr Val Asn Leu  Lys Gly Val 
    1985                 1990                 1995             


Glu Glu  Asn Ser Leu Asp Ser  Phe Val Phe Asp Thr  Leu Ile Pro 
    2000                 2005                 2010             


Lys Pro  Ile Thr Gln Arg Tyr  Phe Asn Leu Leu Met  Glu His His 
    2015                 2020                 2025             


Arg Ile  Ile Leu Ser Gly Pro  Ser Gly Thr Gly Lys  Thr Tyr Leu 
    2030                 2035                 2040             


Ala Asn  Lys Leu Ala Glu Tyr  Val Ile Thr Lys Ser  Gly Arg Lys 
    2045                 2050                 2055             


Lys Thr  Glu Asp Ala Ile Ala  Thr Phe Asn Val Asp  His Lys Ser 
    2060                 2065                 2070             


Ser Lys  Glu Leu Gln Gln Tyr  Leu Ala Asn Leu Ala  Glu Gln Cys 
    2075                 2080                 2085             


Ser Ala  Asp Asn Asn Gly Val  Glu Leu Pro Val Val  Ile Ile Leu 
    2090                 2095                 2100             


Asp Asn  Leu His His Val Gly  Ser Leu Ser Asp Ile  Phe Asn Gly 
    2105                 2110                 2115             


Phe Leu  Asn Cys Lys Tyr Asn  Lys Cys Pro Tyr Ile  Ile Gly Thr 
    2120                 2125                 2130             


Met Asn  Gln Gly Val Ser Ser  Ser Pro Asn Leu Glu  Leu His His 
    2135                 2140                 2145             


Asn Phe  Arg Trp Val Leu Cys  Ala Asn His Thr Glu  Pro Val Lys 
    2150                 2155                 2160             


Gly Phe  Leu Gly Arg Tyr Leu  Arg Arg Lys Leu Ile  Glu Ile Glu 
    2165                 2170                 2175             


Ile Glu  Arg Asn Ile Arg Asn  Asn Asp Leu Val Lys  Ile Ile Asp 
    2180                 2185                 2190             


Trp Ile  Pro Lys Thr Trp His  His Leu Asn Ser Phe  Leu Glu Thr 
    2195                 2200                 2205             


His Ser  Ser Ser Asp Val Thr  Ile Gly Pro Arg Leu  Phe Leu Pro 
    2210                 2215                 2220             


Cys Pro  Met Asp Val Glu Gly  Ser Arg Val Trp Phe  Met Asp Leu 
    2225                 2230                 2235             


Trp Asn  Tyr Ser Leu Val Pro  Tyr Ile Leu Glu Ala  Val Arg Glu 
    2240                 2245                 2250             


Gly Leu  Gln Met Tyr Gly Lys  Arg Thr Pro Trp Glu  Asp Pro Ser 
    2255                 2260                 2265             


Lys Trp  Val Leu Asp Thr Tyr  Pro Trp Ser Ser Ala  Thr Leu Pro 
    2270                 2275                 2280             


Gln Glu  Ser Pro Ala Leu Leu  Gln Leu Arg Pro Glu  Asp Val Gly 
    2285                 2290                 2295             


Tyr Glu  Ser Cys Thr Ser Thr  Lys Glu Ala Thr Thr  Ser Lys His 
    2300                 2305                 2310             


Ile Pro  Gln Thr Asp Thr Glu  Gly Asp Pro Leu Met  Asn Met Leu 
    2315                 2320                 2325             


Met Lys  Leu Gln Glu Ala Ala  Asn Tyr Ser Ser Thr  Gln Ser Cys 
    2330                 2335                 2340             


Asp Ser  Glu Ser Thr Ser His  His Glu Asp Ile Leu  Asp Ser Ser 
    2345                 2350                 2355             


Leu Glu  Ser Thr Leu 
    2360             


<210>  3988
<211>  556
<212>  PRT
<213>  homo sapiens

<400>  3988

Met Asn Glu Gly Ala Pro Gly Asp Ser Asp Leu Glu Thr Glu Ala Arg 
1               5                   10                  15      


Val Pro Trp Ser Ile Met Gly His Cys Leu Arg Thr Gly Gln Ala Arg 
            20                  25                  30          


Met Ser Ala Thr Pro Thr Pro Ala Gly Glu Gly Ala Arg Arg Asp Glu 
        35                  40                  45              


Leu Phe Gly Ile Leu Gln Ile Leu His Gln Cys Ile Leu Ser Ser Gly 
    50                  55                  60                  


Asp Ala Phe Val Leu Thr Gly Val Cys Cys Ser Trp Arg Gln Asn Gly 
65                  70                  75                  80  


Lys Pro Pro Tyr Ser Gln Lys Glu Asp Lys Glu Val Gln Thr Gly Tyr 
                85                  90                  95      


Met Asn Ala Gln Ile Glu Ile Ile Pro Cys Lys Ile Cys Gly Asp Lys 
            100                 105                 110         


Ser Ser Gly Ile His Tyr Gly Val Ile Thr Cys Glu Gly Cys Lys Gly 
        115                 120                 125             


Phe Phe Arg Arg Ser Gln Gln Ser Asn Ala Thr Tyr Ser Cys Pro Arg 
    130                 135                 140                 


Gln Lys Asn Cys Leu Ile Asp Arg Thr Ser Arg Asn Arg Cys Gln His 
145                 150                 155                 160 


Cys Arg Leu Gln Lys Cys Leu Ala Val Gly Met Ser Arg Asp Ala Val 
                165                 170                 175     


Lys Phe Gly Arg Met Ser Lys Lys Gln Arg Asp Ser Leu Tyr Ala Glu 
            180                 185                 190         


Val Gln Lys His Arg Met Gln Gln Gln Gln Arg Asp His Gln Gln Gln 
        195                 200                 205             


Pro Gly Glu Ala Glu Pro Leu Thr Pro Thr Tyr Asn Ile Ser Ala Asn 
    210                 215                 220                 


Gly Leu Thr Glu Leu His Asp Asp Leu Ser Asn Tyr Ile Asp Gly His 
225                 230                 235                 240 


Thr Pro Glu Gly Ser Lys Ala Asp Ser Ala Val Ser Ser Phe Tyr Leu 
                245                 250                 255     


Asp Ile Gln Pro Ser Pro Asp Gln Ser Gly Leu Asp Ile Asn Gly Ile 
            260                 265                 270         


Lys Pro Glu Pro Ile Cys Asp Tyr Thr Pro Ala Ser Gly Phe Phe Pro 
        275                 280                 285             


Tyr Cys Ser Phe Thr Asn Gly Glu Thr Ser Pro Thr Val Ser Met Ala 
    290                 295                 300                 


Glu Leu Glu His Leu Ala Gln Asn Ile Ser Lys Ser His Leu Glu Thr 
305                 310                 315                 320 


Cys Gln Tyr Leu Arg Glu Glu Leu Gln Gln Ile Thr Trp Gln Thr Phe 
                325                 330                 335     


Leu Gln Glu Glu Ile Glu Asn Tyr Gln Asn Lys Gln Arg Glu Val Met 
            340                 345                 350         


Trp Gln Leu Cys Ala Ile Lys Ile Thr Glu Ala Ile Gln Tyr Val Val 
        355                 360                 365             


Glu Phe Ala Lys Arg Ile Asp Gly Phe Met Glu Leu Cys Gln Asn Asp 
    370                 375                 380                 


Gln Ile Val Leu Leu Lys Ala Gly Ser Leu Glu Val Val Phe Ile Arg 
385                 390                 395                 400 


Met Cys Arg Ala Phe Asp Ser Gln Asn Asn Thr Val Tyr Phe Asp Gly 
                405                 410                 415     


Lys Tyr Ala Ser Pro Asp Val Phe Lys Ser Leu Gly Cys Glu Asp Phe 
            420                 425                 430         


Ile Ser Phe Val Phe Glu Phe Gly Lys Ser Leu Cys Ser Met His Leu 
        435                 440                 445             


Thr Glu Asp Glu Ile Ala Leu Phe Ser Ala Phe Val Leu Met Ser Ala 
    450                 455                 460                 


Asp Arg Ser Trp Leu Gln Glu Lys Val Lys Ile Glu Lys Leu Gln Gln 
465                 470                 475                 480 


Lys Ile Gln Leu Ala Leu Gln His Val Leu Gln Lys Asn His Arg Glu 
                485                 490                 495     


Asp Gly Ile Leu Thr Lys Leu Ile Cys Lys Val Ser Thr Leu Arg Ala 
            500                 505                 510         


Leu Cys Gly Arg His Thr Glu Lys Leu Met Ala Phe Lys Ala Ile Tyr 
        515                 520                 525             


Pro Asp Ile Val Arg Leu His Phe Pro Pro Leu Tyr Lys Glu Leu Phe 
    530                 535                 540                 


Thr Ser Glu Phe Glu Pro Ala Met Gln Ile Asp Gly 
545                 550                 555     


<210>  3989
<211>  523
<212>  PRT
<213>  homo sapiens

<400>  3989

Met Glu Ser Ala Pro Ala Ala Pro Asp Pro Ala Ala Ser Glu Pro Gly 
1               5                   10                  15      


Ser Ser Gly Ala Asp Ala Ala Ala Gly Ser Arg Glu Thr Pro Leu Asn 
            20                  25                  30          


Gln Glu Ser Ala Arg Lys Ser Glu Pro Pro Ala Pro Val Arg Arg Gln 
        35                  40                  45              


Ser Tyr Ser Ser Thr Ser Arg Gly Ile Ser Val Thr Lys Lys Thr His 
    50                  55                  60                  


Thr Ser Gln Ile Glu Ile Ile Pro Cys Lys Ile Cys Gly Asp Lys Ser 
65                  70                  75                  80  


Ser Gly Ile His Tyr Gly Val Ile Thr Cys Glu Gly Cys Lys Gly Phe 
                85                  90                  95      


Phe Arg Arg Ser Gln Gln Ser Asn Ala Thr Tyr Ser Cys Pro Arg Gln 
            100                 105                 110         


Lys Asn Cys Leu Ile Asp Arg Thr Ser Arg Asn Arg Cys Gln His Cys 
        115                 120                 125             


Arg Leu Gln Lys Cys Leu Ala Val Gly Met Ser Arg Asp Ala Val Lys 
    130                 135                 140                 


Phe Gly Arg Met Ser Lys Lys Gln Arg Asp Ser Leu Tyr Ala Glu Val 
145                 150                 155                 160 


Gln Lys His Arg Met Gln Gln Gln Gln Arg Asp His Gln Gln Gln Pro 
                165                 170                 175     


Gly Glu Ala Glu Pro Leu Thr Pro Thr Tyr Asn Ile Ser Ala Asn Gly 
            180                 185                 190         


Leu Thr Glu Leu His Asp Asp Leu Ser Asn Tyr Ile Asp Gly His Thr 
        195                 200                 205             


Pro Glu Gly Ser Lys Ala Asp Ser Ala Val Ser Ser Phe Tyr Leu Asp 
    210                 215                 220                 


Ile Gln Pro Ser Pro Asp Gln Ser Gly Leu Asp Ile Asn Gly Ile Lys 
225                 230                 235                 240 


Pro Glu Pro Ile Cys Asp Tyr Thr Pro Ala Ser Gly Phe Phe Pro Tyr 
                245                 250                 255     


Cys Ser Phe Thr Asn Gly Glu Thr Ser Pro Thr Val Ser Met Ala Glu 
            260                 265                 270         


Leu Glu His Leu Ala Gln Asn Ile Ser Lys Ser His Leu Glu Thr Cys 
        275                 280                 285             


Gln Tyr Leu Arg Glu Glu Leu Gln Gln Ile Thr Trp Gln Thr Phe Leu 
    290                 295                 300                 


Gln Glu Glu Ile Glu Asn Tyr Gln Asn Lys Gln Arg Glu Val Met Trp 
305                 310                 315                 320 


Gln Leu Cys Ala Ile Lys Ile Thr Glu Ala Ile Gln Tyr Val Val Glu 
                325                 330                 335     


Phe Ala Lys Arg Ile Asp Gly Phe Met Glu Leu Cys Gln Asn Asp Gln 
            340                 345                 350         


Ile Val Leu Leu Lys Ala Gly Ser Leu Glu Val Val Phe Ile Arg Met 
        355                 360                 365             


Cys Arg Ala Phe Asp Ser Gln Asn Asn Thr Val Tyr Phe Asp Gly Lys 
    370                 375                 380                 


Tyr Ala Ser Pro Asp Val Phe Lys Ser Leu Gly Cys Glu Asp Phe Ile 
385                 390                 395                 400 


Ser Phe Val Phe Glu Phe Gly Lys Ser Leu Cys Ser Met His Leu Thr 
                405                 410                 415     


Glu Asp Glu Ile Ala Leu Phe Ser Ala Phe Val Leu Met Ser Ala Asp 
            420                 425                 430         


Arg Ser Trp Leu Gln Glu Lys Val Lys Ile Glu Lys Leu Gln Gln Lys 
        435                 440                 445             


Ile Gln Leu Ala Leu Gln His Val Leu Gln Lys Asn His Arg Glu Asp 
    450                 455                 460                 


Gly Ile Leu Thr Lys Leu Ile Cys Lys Val Ser Thr Leu Arg Ala Leu 
465                 470                 475                 480 


Cys Gly Arg His Thr Glu Lys Leu Met Ala Phe Lys Ala Ile Tyr Pro 
                485                 490                 495     


Asp Ile Val Arg Leu His Phe Pro Pro Leu Tyr Lys Glu Leu Phe Thr 
            500                 505                 510         


Ser Glu Phe Glu Pro Ala Met Gln Ile Asp Gly 
        515                 520             


<210>  3990
<211>  727
<212>  PRT
<213>  homo sapiens

<400>  3990

Met Asn Gln Lys Leu Leu Lys Leu Glu Asn Leu Leu Arg Phe His Thr 
1               5                   10                  15      


Ile Tyr Arg Gln Leu His Ser Leu Cys Gln Arg Arg Ala Leu Arg Gln 
            20                  25                  30          


Trp Arg His Gly Phe Ser Ser Ala Tyr Pro Val Trp Thr Ala Gln Leu 
        35                  40                  45              


Cys Ala Trp Pro Trp Pro Thr Asp Val Leu Thr Gly Ala Ala Leu Ser 
    50                  55                  60                  


Gln Tyr Arg Leu Leu Val Thr Lys Lys Glu Glu Gly Pro Trp Lys Ser 
65                  70                  75                  80  


Gln Leu Ser Ser Thr Lys Ser Lys Lys Val Val Glu Val Trp Ile Gly 
                85                  90                  95      


Met Thr Ile Glu Glu Leu Ala Arg Ala Met Glu Lys Asn Thr Asp Tyr 
            100                 105                 110         


Val Tyr Glu Ala Leu Leu Asn Thr Asp Ile Asp Ile Asp Ser Leu Glu 
        115                 120                 125             


Ala Asp Ser His Leu Asp Glu Val Trp Ile Lys Glu Val Ile Thr Lys 
    130                 135                 140                 


Ala Gly Met Lys Leu Lys Trp Ser Lys Leu Lys Gln Asp Lys Val Arg 
145                 150                 155                 160 


Lys Asn Lys Asp Ala Val Arg Arg Pro Gln Ala Asp Pro Ala Leu Leu 
                165                 170                 175     


Thr Pro Arg Ser Pro Val Val Thr Ile Met Gly His Val Asp His Gly 
            180                 185                 190         


Lys Thr Thr Leu Leu Asp Lys Phe Arg Lys Thr Gln Val Ala Ala Val 
        195                 200                 205             


Glu Thr Gly Gly Ile Thr Gln His Ile Gly Ala Phe Leu Val Ser Leu 
    210                 215                 220                 


Pro Ser Gly Glu Lys Ile Thr Phe Leu Asp Thr Pro Gly His Ala Ala 
225                 230                 235                 240 


Phe Ser Ala Met Arg Ala Arg Gly Ala Gln Val Thr Asp Ile Val Val 
                245                 250                 255     


Leu Val Val Ala Ala Asp Asp Gly Val Met Lys Gln Thr Val Glu Ser 
            260                 265                 270         


Ile Gln His Ala Lys Asp Ala Gln Val Pro Ile Ile Leu Ala Val Asn 
        275                 280                 285             


Lys Cys Asp Lys Ala Glu Ala Asp Pro Glu Lys Val Lys Lys Glu Leu 
    290                 295                 300                 


Leu Ala Tyr Asp Val Val Cys Glu Asp Tyr Gly Gly Asp Val Gln Ala 
305                 310                 315                 320 


Val Pro Val Ser Ala Leu Thr Gly Asp Asn Leu Met Ala Leu Ala Glu 
                325                 330                 335     


Ala Thr Val Ala Leu Ala Glu Met Leu Glu Leu Lys Ala Asp Pro Asn 
            340                 345                 350         


Gly Pro Val Glu Gly Thr Val Ile Glu Ser Phe Thr Asp Lys Gly Arg 
        355                 360                 365             


Gly Leu Val Thr Thr Ala Ile Ile Gln Arg Gly Thr Leu Arg Lys Gly 
    370                 375                 380                 


Ser Val Leu Val Ala Gly Lys Cys Trp Ala Lys Val Arg Leu Met Phe 
385                 390                 395                 400 


Asp Glu Asn Gly Lys Thr Ile Asp Glu Ala Tyr Pro Ser Met Pro Val 
                405                 410                 415     


Gly Ile Thr Gly Trp Arg Asp Leu Pro Ser Ala Gly Glu Glu Ile Leu 
            420                 425                 430         


Glu Val Glu Ser Glu Pro Arg Ala Arg Glu Val Val Asp Trp Arg Lys 
        435                 440                 445             


Tyr Glu Gln Glu Gln Glu Lys Gly Gln Glu Asp Leu Lys Ile Ile Glu 
    450                 455                 460                 


Glu Lys Arg Lys Glu His Lys Glu Ala His Gln Lys Ala Arg Glu Lys 
465                 470                 475                 480 


Tyr Gly His Leu Leu Trp Lys Lys Arg Ser Ile Leu Arg Phe Leu Glu 
                485                 490                 495     


Arg Lys Glu Gln Ile Pro Leu Lys Pro Lys Glu Lys Arg Glu Arg Asp 
            500                 505                 510         


Ser Asn Val Leu Ser Val Ile Ile Lys Gly Asp Val Asp Gly Ser Val 
        515                 520                 525             


Glu Ala Ile Leu Asn Ile Ile Asp Thr Tyr Asp Ala Ser His Glu Cys 
    530                 535                 540                 


Glu Leu Glu Leu Val His Phe Gly Val Gly Asp Val Ser Ala Asn Asp 
545                 550                 555                 560 


Val Asn Leu Ala Glu Thr Phe Asp Gly Val Ile Tyr Gly Phe Asn Val 
                565                 570                 575     


Asn Ala Gly Asn Val Ile Gln Gln Ser Ala Ala Lys Lys Gly Val Lys 
            580                 585                 590         


Ile Lys Leu His Lys Ile Ile Tyr Arg Leu Val Glu Asp Leu Gln Glu 
        595                 600                 605             


Glu Leu Ser Ser Arg Leu Pro Cys Ala Val Glu Glu His Pro Val Gly 
    610                 615                 620                 


Glu Ala Ser Ile Leu Ala Thr Phe Ser Val Thr Glu Gly Lys Lys Lys 
625                 630                 635                 640 


Val Pro Val Ala Gly Cys Arg Val Gln Lys Gly Gln Leu Glu Lys Gln 
                645                 650                 655     


Lys Lys Phe Lys Leu Thr Arg Asn Gly His Val Ile Trp Lys Gly Ser 
            660                 665                 670         


Leu Thr Ser Leu Lys His His Lys Asp Asp Ile Ser Ile Val Lys Thr 
        675                 680                 685             


Gly Met Asp Cys Gly Leu Ser Leu Asp Glu Asp Asn Met Glu Phe Gln 
    690                 695                 700                 


Val Gly Asp Arg Ile Val Cys Tyr Glu Glu Lys Gln Ile Gln Ala Lys 
705                 710                 715                 720 


Thr Ser Trp Asp Pro Gly Phe 
                725         


<210>  3991
<211>  78
<212>  PRT
<213>  homo sapiens

<400>  3991

Met Ser Glu Val Leu Pro Tyr Gly Asp Glu Lys Leu Ser Pro Tyr Gly 
1               5                   10                  15      


Asp Gly Gly Asp Val Gly Gln Ile Phe Ser Cys Arg Leu Gln Asp Thr 
            20                  25                  30          


Asn Asn Phe Phe Gly Ala Gly Gln Asn Lys Arg Pro Pro Lys Leu Gly 
        35                  40                  45              


Gln Ile Gly Arg Ser Lys Arg Val Val Ile Glu Asp Asp Arg Ile Asp 
    50                  55                  60                  


Asp Val Leu Lys Asn Met Thr Asp Lys Ala Pro Pro Gly Val 
65                  70                  75              


<210>  3992
<211>  499
<212>  PRT
<213>  homo sapiens

<400>  3992

Met Ser Phe Gly Ser Glu His Tyr Leu Cys Ser Ser Ser Ser Tyr Arg 
1               5                   10                  15      


Lys Val Phe Gly Asp Gly Ser Arg Leu Ser Ala Arg Leu Ser Gly Ala 
            20                  25                  30          


Gly Gly Ala Gly Gly Phe Arg Ser Gln Ser Leu Ser Arg Ser Asn Val 
        35                  40                  45              


Ala Ser Ser Ala Ala Cys Ser Ser Ala Ser Ser Leu Gly Leu Gly Leu 
    50                  55                  60                  


Ala Tyr Arg Arg Pro Pro Ala Ser Asp Gly Leu Asp Leu Ser Gln Ala 
65                  70                  75                  80  


Ala Ala Arg Thr Asn Glu Tyr Lys Ile Ile Arg Thr Asn Glu Lys Glu 
                85                  90                  95      


Gln Leu Gln Gly Leu Asn Asp Arg Phe Ala Val Phe Ile Glu Lys Val 
            100                 105                 110         


His Gln Leu Glu Thr Gln Asn Arg Ala Leu Glu Ala Glu Leu Ala Ala 
        115                 120                 125             


Leu Arg Gln Arg His Ala Glu Pro Ser Arg Val Gly Glu Leu Phe Gln 
    130                 135                 140                 


Arg Glu Leu Arg Asp Leu Arg Ala Gln Leu Glu Glu Ala Ser Ser Ala 
145                 150                 155                 160 


Arg Ser Gln Ala Leu Leu Glu Arg Asp Gly Leu Ala Glu Glu Val Gln 
                165                 170                 175     


Arg Leu Arg Ala Arg Cys Glu Glu Glu Ser Arg Gly Arg Glu Gly Ala 
            180                 185                 190         


Glu Arg Ala Leu Lys Ala Gln Gln Arg Asp Val Asp Gly Ala Thr Leu 
        195                 200                 205             


Ala Arg Leu Asp Leu Glu Lys Lys Val Glu Ser Leu Leu Asp Glu Leu 
    210                 215                 220                 


Ala Phe Val Arg Gln Val His Asp Glu Glu Val Ala Glu Leu Leu Ala 
225                 230                 235                 240 


Thr Leu Gln Ala Ser Ser Gln Ala Ala Ala Glu Val Asp Val Thr Val 
                245                 250                 255     


Ala Lys Pro Asp Leu Thr Ser Ala Leu Arg Glu Ile Arg Ala Gln Tyr 
            260                 265                 270         


Glu Ser Leu Ala Ala Lys Asn Leu Gln Ser Ala Glu Glu Trp Tyr Lys 
        275                 280                 285             


Ser Lys Phe Ala Asn Leu Asn Glu Gln Ala Ala Arg Ser Thr Glu Ala 
    290                 295                 300                 


Ile Arg Ala Ser Arg Glu Glu Ile His Glu Tyr Arg Arg Gln Leu Gln 
305                 310                 315                 320 


Ala Arg Thr Ile Glu Ile Glu Gly Leu Arg Gly Ala Asn Glu Ser Leu 
                325                 330                 335     


Glu Arg Gln Ile Leu Glu Leu Glu Glu Arg His Ser Ala Glu Val Ala 
            340                 345                 350         


Gly Tyr Gln Asp Ser Ile Gly Gln Leu Glu Asn Asp Leu Arg Asn Thr 
        355                 360                 365             


Lys Ser Glu Met Ala Arg His Leu Arg Glu Tyr Gln Asp Leu Leu Asn 
    370                 375                 380                 


Val Lys Met Ala Leu Asp Ile Glu Ile Ala Ala Tyr Arg Lys Leu Leu 
385                 390                 395                 400 


Glu Gly Glu Glu Thr Arg Phe Ser Thr Ser Gly Leu Ser Ile Ser Gly 
                405                 410                 415     


Leu Asn Pro Leu Pro Asn Pro Ser Tyr Leu Leu Pro Pro Arg Ile Leu 
            420                 425                 430         


Ser Ala Thr Thr Ser Lys Val Ser Ser Thr Gly Leu Ser Leu Lys Lys 
        435                 440                 445             


Glu Glu Glu Glu Glu Glu Ala Ser Lys Val Ala Ser Lys Lys Thr Ser 
    450                 455                 460                 


Gln Ile Gly Glu Ser Phe Glu Glu Ile Leu Glu Glu Thr Val Ile Ser 
465                 470                 475                 480 


Thr Lys Lys Thr Glu Lys Ser Asn Ile Glu Glu Thr Thr Ile Ser Ser 
                485                 490                 495     


Gln Lys Ile 
            


<210>  3993
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  3993

Met Ala Ser Gln Pro Pro Glu Asp Thr Ala Glu Ser Gln Ala Ser Asp 
1               5                   10                  15      


Glu Leu Glu Cys Lys Ile Cys Tyr Asn Arg Tyr Asn Leu Lys Gln Arg 
            20                  25                  30          


Lys Pro Lys Val Leu Glu Cys Cys His Arg Val Cys Ala Lys Cys Leu 
        35                  40                  45              


Tyr Lys Ile Ile Asp Phe Gly Asp Ser Pro Gln Gly Val Ile Val Cys 
    50                  55                  60                  


Pro Phe Cys Arg Phe Glu Thr Cys Leu Pro Asp Asp Glu Val Ser Ser 
65                  70                  75                  80  


Leu Pro Asp Asp Asn Asn Ile Leu Val Asn Leu Thr Cys Gly Gly Lys 
                85                  90                  95      


Gly Lys Lys Cys Leu Pro Glu Asn Pro Thr Glu Leu Leu Leu Thr Pro 
            100                 105                 110         


Lys Arg Leu Ala Ser Leu Val Ser Pro Ser His Thr Ser Ser Asn Cys 
        115                 120                 125             


Leu Val Ile Thr Ile Met Glu Val Gln Arg Glu Ser Ser Pro Ser Leu 
    130                 135                 140                 


Ser Ser Thr Pro Val Val Glu Phe Tyr Arg Pro Ala Ser Phe Asp Ser 
145                 150                 155                 160 


Val Thr Thr Val Ser His Asn Trp Thr Val Trp Asn Cys Thr Ser Leu 
                165                 170                 175     


Leu Phe Gln Thr Ser Ile Arg Val Leu Val Trp Leu Leu Gly Leu Leu 
            180                 185                 190         


Tyr Phe Ser Ser Leu Pro Leu Gly Ile Tyr Leu Leu Val Ser Lys Lys 
        195                 200                 205             


Val Thr Leu Gly Val Val Phe Val Ser Leu Val Pro Ser Ser Leu Val 
    210                 215                 220                 


Ile Leu Met Val Tyr Gly Phe Cys Gln Cys Val Cys His Glu Phe Leu 
225                 230                 235                 240 


Asp Cys Met Ala Pro Pro Ser 
                245         


<210>  3994
<211>  846
<212>  PRT
<213>  homo sapiens

<400>  3994

Met Phe Lys Cys Trp Ser Val Val Leu Val Leu Gly Phe Ile Phe Leu 
1               5                   10                  15      


Glu Ser Glu Gly Arg Pro Thr Lys Glu Gly Gly Tyr Gly Leu Lys Ser 
            20                  25                  30          


Tyr Gln Pro Leu Met Arg Leu Arg His Lys Glu Lys Asn Gln Glu Ser 
        35                  40                  45              


Ser Arg Val Lys Gly Phe Met Ile Gln Asp Gly Pro Phe Gly Ser Cys 
    50                  55                  60                  


Glu Asn Lys Tyr Cys Gly Leu Gly Arg His Cys Val Thr Ser Arg Glu 
65                  70                  75                  80  


Thr Gly Gln Ala Glu Cys Ala Cys Met Asp Leu Cys Lys Arg His Tyr 
                85                  90                  95      


Lys Pro Val Cys Gly Ser Asp Gly Glu Phe Tyr Glu Asn His Cys Glu 
            100                 105                 110         


Val His Arg Ala Ala Cys Leu Lys Lys Gln Lys Ile Thr Ile Val His 
        115                 120                 125             


Asn Glu Asp Cys Phe Phe Lys Gly Asp Lys Cys Lys Thr Thr Glu Tyr 
    130                 135                 140                 


Ser Lys Met Lys Asn Met Leu Leu Asp Leu Gln Asn Gln Lys Tyr Ile 
145                 150                 155                 160 


Met Gln Glu Asn Glu Asn Pro Asn Gly Asp Asp Ile Ser Arg Lys Lys 
                165                 170                 175     


Leu Leu Val Asp Gln Met Phe Lys Tyr Phe Asp Ala Asp Ser Asn Gly 
            180                 185                 190         


Leu Val Asp Ile Asn Glu Leu Thr Gln Val Ile Lys Gln Glu Glu Leu 
        195                 200                 205             


Gly Lys Asp Leu Phe Asp Cys Thr Leu Tyr Val Leu Leu Lys Tyr Asp 
    210                 215                 220                 


Asp Phe Asn Ala Asp Lys His Leu Ala Leu Glu Glu Phe Tyr Arg Ala 
225                 230                 235                 240 


Phe Gln Val Ile Gln Leu Ser Leu Pro Glu Asp Gln Lys Leu Ser Ile 
                245                 250                 255     


Thr Ala Ala Thr Val Gly Gln Ser Ala Val Leu Ser Cys Ala Ile Gln 
            260                 265                 270         


Gly Thr Leu Arg Pro Pro Ile Ile Trp Lys Arg Asn Asn Ile Ile Leu 
        275                 280                 285             


Asn Asn Leu Asp Leu Glu Asp Ile Asn Asp Phe Gly Asp Asp Gly Ser 
    290                 295                 300                 


Leu Tyr Ile Thr Lys Val Thr Thr Thr His Val Gly Asn Tyr Thr Cys 
305                 310                 315                 320 


Tyr Ala Asp Gly Tyr Glu Gln Val Tyr Gln Thr His Ile Phe Gln Val 
                325                 330                 335     


Asn Val Pro Pro Val Ile Arg Val Tyr Pro Glu Ser Gln Ala Arg Glu 
            340                 345                 350         


Pro Gly Val Thr Ala Ser Leu Arg Cys His Ala Glu Gly Ile Pro Lys 
        355                 360                 365             


Pro Gln Leu Gly Trp Leu Lys Asn Gly Ile Asp Ile Thr Pro Lys Leu 
    370                 375                 380                 


Ser Lys Gln Leu Thr Leu Gln Ala Asn Gly Ser Glu Val His Ile Ser 
385                 390                 395                 400 


Asn Val Arg Tyr Glu Asp Thr Gly Ala Tyr Thr Cys Ile Ala Lys Asn 
                405                 410                 415     


Glu Ala Gly Val Asp Glu Asp Ile Ser Ser Leu Phe Val Glu Asp Ser 
            420                 425                 430         


Ala Arg Lys Thr Leu Ala Asn Ile Leu Trp Arg Glu Glu Gly Leu Gly 
        435                 440                 445             


Ile Gly Asn Met Phe Tyr Val Phe Tyr Glu Asp Gly Ile Lys Val Ile 
    450                 455                 460                 


Gln Pro Ile Glu Cys Glu Phe Gln Arg His Ile Lys Pro Ser Glu Lys 
465                 470                 475                 480 


Leu Leu Gly Phe Gln Asp Glu Val Cys Pro Lys Ala Glu Gly Asp Glu 
                485                 490                 495     


Val Gln Arg Cys Val Trp Ala Ser Ala Val Asn Val Lys Asp Lys Phe 
            500                 505                 510         


Ile Tyr Val Ala Gln Pro Thr Leu Asp Arg Val Leu Ile Val Asp Val 
        515                 520                 525             


Gln Ser Gln Lys Val Val Gln Ala Val Ser Thr Asp Pro Val Pro Val 
    530                 535                 540                 


Lys Leu His Tyr Asp Lys Ser His Asp Gln Val Trp Val Leu Ser Trp 
545                 550                 555                 560 


Gly Thr Leu Glu Lys Thr Ser Pro Thr Leu Gln Val Ile Thr Leu Ala 
                565                 570                 575     


Ser Gly Asn Val Pro His His Thr Ile His Thr Gln Pro Val Gly Lys 
            580                 585                 590         


Gln Phe Asp Arg Val Asp Asp Phe Phe Ile Pro Thr Thr Thr Leu Ile 
        595                 600                 605             


Ile Thr His Met Arg Phe Gly Phe Ile Leu His Lys Asp Glu Ala Ala 
    610                 615                 620                 


Leu Gln Lys Ile Asp Leu Glu Thr Met Ser Tyr Ile Lys Thr Ile Asn 
625                 630                 635                 640 


Leu Lys Asp Tyr Lys Cys Val Pro Gln Ser Leu Ala Tyr Thr His Leu 
                645                 650                 655     


Gly Gly Tyr Tyr Phe Ile Gly Cys Lys Pro Asp Ser Thr Gly Ala Val 
            660                 665                 670         


Ser Pro Gln Val Met Val Asp Gly Val Thr Asp Ser Val Ile Gly Phe 
        675                 680                 685             


Asn Ser Asp Val Thr Gly Thr Pro Tyr Val Ser Pro Asp Gly His Tyr 
    690                 695                 700                 


Leu Val Ser Ile Asn Asp Val Lys Gly Leu Val Arg Val Gln Tyr Ile 
705                 710                 715                 720 


Thr Ile Arg Gly Glu Ile Gln Glu Ala Phe Asp Ile Tyr Thr Asn Leu 
                725                 730                 735     


His Ile Ser Asp Leu Ala Phe Gln Pro Ser Phe Thr Glu Ala His Gln 
            740                 745                 750         


Tyr Asn Ile Tyr Gly Ser Ser Ser Thr Gln Thr Asp Val Leu Phe Val 
        755                 760                 765             


Glu Leu Ser Ser Gly Lys Val Lys Met Ile Lys Ser Leu Lys Glu Pro 
    770                 775                 780                 


Leu Lys Ala Glu Glu Trp Pro Trp Asn Arg Lys Asn Arg Gln Ile Gln 
785                 790                 795                 800 


Asp Ser Gly Leu Phe Gly Gln Tyr Leu Met Thr Pro Ser Lys Asp Ser 
                805                 810                 815     


Leu Phe Ile Leu Asp Gly Arg Leu Asn Lys Leu Asn Cys Glu Ile Thr 
            820                 825                 830         


Glu Val Glu Lys Gly Asn Thr Val Ile Trp Val Gly Asp Ala 
        835                 840                 845     


<210>  3995
<211>  671
<212>  PRT
<213>  homo sapiens

<400>  3995

Met Gln Phe Val Ser Thr Arg Pro Gln Pro Gln Gln Leu Gly Ile Gln 
1               5                   10                  15      


Gly Leu Gly Leu Asp Ser Gly Ser Trp Ser Trp Ala Gln Ala Leu Pro 
            20                  25                  30          


Pro Glu Glu Val Cys His Gln Glu Pro Ala Leu Arg Gly Glu Met Ala 
        35                  40                  45              


Glu Gly Met Pro Pro Met Gln Ala Gln Glu Trp Asp Met Asp Ala Arg 
    50                  55                  60                  


Arg Pro Met Pro Phe Gln Phe Pro Pro Phe Pro Asp Arg Ala Pro Val 
65                  70                  75                  80  


Phe Pro Asp Arg Met Met Arg Glu Pro Gln Leu Pro Thr Ala Glu Ile 
                85                  90                  95      


Ser Leu Trp Thr Val Val Ala Ala Ile Gln Ala Val Glu Arg Lys Val 
            100                 105                 110         


Asp Ala Gln Ala Ser Gln Leu Leu Asn Leu Glu Gly Arg Thr Gly Thr 
        115                 120                 125             


Ala Glu Lys Lys Leu Ala Asp Cys Glu Lys Thr Ala Val Glu Phe Gly 
    130                 135                 140                 


Asn His Met Glu Ser Lys Trp Ala Val Leu Gly Thr Leu Leu Gln Glu 
145                 150                 155                 160 


Tyr Gly Leu Leu Gln Arg Arg Leu Glu Asn Leu Glu Asn Leu Leu Arg 
                165                 170                 175     


Asn Arg Asn Phe Trp Val Leu Arg Leu Pro Pro Gly Ser Lys Gly Glu 
            180                 185                 190         


Ala Pro Lys Val Pro Val Thr Phe Val Asp Ile Ala Val Tyr Phe Ser 
        195                 200                 205             


Glu Asp Glu Trp Lys Asn Leu Asp Glu Trp Gln Lys Glu Leu Tyr Asn 
    210                 215                 220                 


Asn Leu Val Lys Glu Asn Tyr Lys Thr Leu Met Ser Leu Asp Ala Glu 
225                 230                 235                 240 


Gly Ser Val Pro Lys Pro Asp Ala Pro Val Gln Ala Glu Pro Arg Glu 
                245                 250                 255     


Glu Pro Cys Val Trp Glu Gln Arg His Pro Glu Glu Arg Glu Ile Pro 
            260                 265                 270         


Met Asp Pro Glu Ala Gly Ala Glu Pro Leu Val Pro Ala Gln Asp Ala 
        275                 280                 285             


Ser Ser Gln Val Lys Arg Glu Asp Thr Leu Cys Val Arg Gly Gln Arg 
    290                 295                 300                 


Gly Leu Glu Glu Arg Ala Ile Pro Thr Glu Ser Ile Thr Asp Ser Pro 
305                 310                 315                 320 


Ile Ser Ala Gln Asp Leu Leu Ser Arg Ile Lys Gln Glu Glu His Gln 
                325                 330                 335     


Cys Val Trp Asp Gln Gln Asp Leu Ala Asp Arg Asp Ile Pro Thr Asp 
            340                 345                 350         


Pro Asn Ser Glu Ser Leu Ile Ser Ala His Asp Ile Leu Ser Trp Ile 
        355                 360                 365             


Lys Gln Glu Glu Gln Pro Tyr Pro Trp Gly Pro Arg Asp Ser Met Asp 
    370                 375                 380                 


Gly Glu Leu Gly Leu Asp Ser Gly Pro Ser Asp Ser Leu Leu Met Val 
385                 390                 395                 400 


Lys Asn Pro Pro Pro Ala Pro Pro Gln Pro Gln Pro Gln Pro Gln Pro 
                405                 410                 415     


Pro Gln Pro Gln Leu Gln Ser Gln Pro Gln Pro Gln Ser Leu Pro Pro 
            420                 425                 430         


Ile Ala Val Ala Glu Asn Pro Gly Gly Pro Pro Ser Arg Gly Leu Leu 
        435                 440                 445             


Asp Asp Gly Phe Gln Val Leu Pro Gly Glu Arg Gly Ser Gly Glu Ala 
    450                 455                 460                 


Pro Pro Gly Gly Asp Arg Ser Thr Gly Gly Gly Gly Gly Asp Gly Gly 
465                 470                 475                 480 


Gly Gly Gly Gly Gly Ala Glu Ala Gly Thr Gly Ala Gly Gly Gly Cys 
                485                 490                 495     


Gly Ser Cys Cys Pro Gly Gly Leu Arg Arg Ser Leu Leu Leu His Gly 
            500                 505                 510         


Ala Arg Ser Lys Pro Tyr Ser Cys Pro Glu Cys Gly Lys Ser Phe Gly 
        515                 520                 525             


Val Arg Lys Ser Leu Ile Ile His His Arg Ser His Thr Lys Glu Arg 
    530                 535                 540                 


Pro Tyr Glu Cys Ala Glu Cys Glu Lys Ser Phe Asn Cys His Ser Gly 
545                 550                 555                 560 


Leu Ile Arg His Gln Met Thr His Arg Gly Glu Arg Pro Tyr Lys Cys 
                565                 570                 575     


Ser Glu Cys Glu Lys Thr Tyr Ser Arg Lys Glu His Leu Gln Asn His 
            580                 585                 590         


Gln Arg Leu His Thr Gly Glu Arg Pro Phe Gln Cys Ala Leu Cys Gly 
        595                 600                 605             


Lys Ser Phe Ile Arg Lys Gln Asn Leu Leu Lys His Gln Arg Ile His 
    610                 615                 620                 


Thr Gly Glu Arg Pro Tyr Thr Cys Gly Glu Cys Gly Lys Ser Phe Arg 
625                 630                 635                 640 


Tyr Lys Glu Ser Leu Lys Asp His Leu Arg Val His Ser Gly Gly Pro 
                645                 650                 655     


Gly Pro Gly Ala Pro Arg Gln Leu Pro Pro Pro Pro Glu Arg Asp 
            660                 665                 670     


<210>  3996
<211>  526
<212>  PRT
<213>  homo sapiens

<400>  3996

Met Ala Gly Thr Val Arg Thr Ala Cys Leu Val Val Ala Met Leu Leu 
1               5                   10                  15      


Ser Leu Asp Phe Pro Gly Gln Ala Gln Pro Pro Pro Pro Pro Pro Asp 
            20                  25                  30          


Ala Thr Cys His Gln Val Arg Ser Phe Phe Gln Arg Leu Gln Pro Gly 
        35                  40                  45              


Leu Lys Trp Val Pro Glu Thr Pro Val Pro Glu Ala Phe Glu Ile Val 
    50                  55                  60                  


Val Arg His Ala Lys Asn Tyr Thr Asn Ala Met Phe Lys Asn Asn Tyr 
65                  70                  75                  80  


Pro Ser Leu Thr Pro Gln Ala Phe Glu Phe Val Gly Glu Phe Phe Thr 
                85                  90                  95      


Asp Val Ser Leu Tyr Ile Leu Gly Ser Asp Ile Asn Val Asp Asp Met 
            100                 105                 110         


Val Asn Glu Leu Phe Asp Ser Leu Phe Pro Val Ile Tyr Thr Gln Leu 
        115                 120                 125             


Met Asn Pro Gly Leu Pro Asp Ser Ala Leu Asp Ile Asn Glu Cys Leu 
    130                 135                 140                 


Arg Gly Ala Arg Arg Asp Leu Lys Val Phe Gly Asn Phe Pro Lys Leu 
145                 150                 155                 160 


Ile Met Thr Gln Val Ser Lys Ser Leu Gln Val Thr Arg Ile Phe Leu 
                165                 170                 175     


Gln Ala Leu Asn Leu Gly Ile Glu Val Ile Asn Thr Thr Asp His Leu 
            180                 185                 190         


Lys Phe Ser Lys Asp Cys Gly Arg Met Leu Thr Arg Met Trp Tyr Cys 
        195                 200                 205             


Ser Tyr Cys Gln Gly Leu Met Met Val Lys Pro Cys Gly Gly Tyr Cys 
    210                 215                 220                 


Asn Val Val Met Gln Gly Cys Met Ala Gly Val Val Glu Ile Asp Lys 
225                 230                 235                 240 


Tyr Trp Arg Glu Tyr Ile Leu Ser Leu Glu Glu Leu Val Asn Gly Met 
                245                 250                 255     


Tyr Arg Ile Tyr Asp Met Glu Asn Val Leu Leu Gly Leu Phe Ser Thr 
            260                 265                 270         


Ile His Asp Ser Ile Gln Tyr Val Gln Lys Asn Ala Gly Lys Leu Thr 
        275                 280                 285             


Thr Thr Ile Gly Lys Leu Cys Ala His Ser Gln Gln Arg Gln Tyr Arg 
    290                 295                 300                 


Ser Ala Tyr Tyr Pro Glu Asp Leu Phe Ile Asp Lys Lys Val Leu Lys 
305                 310                 315                 320 


Val Ala His Val Glu His Glu Glu Thr Leu Ser Ser Arg Arg Arg Glu 
                325                 330                 335     


Leu Ile Gln Lys Leu Lys Ser Phe Ile Ser Phe Tyr Ser Ala Leu Pro 
            340                 345                 350         


Gly Tyr Ile Cys Ser His Ser Pro Val Ala Glu Asn Asp Thr Leu Cys 
        355                 360                 365             


Trp Asn Gly Gln Glu Leu Val Glu Arg Tyr Ser Gln Lys Ala Ala Arg 
    370                 375                 380                 


Asn Gly Met Lys Asn Gln Phe Asn Leu His Glu Leu Lys Met Lys Gly 
385                 390                 395                 400 


Pro Glu Pro Val Val Ser Gln Ile Ile Asp Lys Leu Lys His Ile Asn 
                405                 410                 415     


Gln Leu Leu Arg Thr Met Ser Met Pro Lys Gly Arg Val Leu Asp Lys 
            420                 425                 430         


Asn Leu Asp Glu Glu Gly Phe Glu Ser Gly Asp Cys Gly Asp Asp Glu 
        435                 440                 445             


Asp Glu Cys Ile Gly Gly Ser Gly Asp Gly Met Ile Lys Val Lys Asn 
    450                 455                 460                 


Gln Leu Arg Phe Leu Ala Glu Leu Ala Tyr Asp Leu Asp Val Asp Asp 
465                 470                 475                 480 


Ala Pro Gly Asn Ser Gln Gln Ala Thr Pro Lys Asp Asn Glu Ile Ser 
                485                 490                 495     


Thr Phe His Asn Leu Gly Asn Val His Ser Pro Leu Lys Leu Leu Thr 
            500                 505                 510         


Ser Met Ala Ile Ser Val Val Cys Phe Phe Phe Leu Val His 
        515                 520                 525     


<210>  3997
<211>  207
<212>  PRT
<213>  homo sapiens

<400>  3997

Met Asn Ser Lys Gly Gln Tyr Pro Thr Gln Pro Thr Tyr Pro Val Gln 
1               5                   10                  15      


Pro Pro Gly Asn Pro Val Tyr Pro Gln Thr Leu His Leu Pro Gln Ala 
            20                  25                  30          


Pro Pro Tyr Thr Asp Ala Pro Pro Ala Tyr Ser Glu Leu Tyr Arg Pro 
        35                  40                  45              


Ser Phe Val His Pro Gly Ala Ala Thr Val Pro Thr Met Ser Ala Ala 
    50                  55                  60                  


Phe Pro Gly Ala Ser Leu Tyr Leu Pro Met Ala Gln Ser Val Ala Val 
65                  70                  75                  80  


Gly Pro Leu Gly Ser Thr Ile Pro Met Ala Tyr Tyr Pro Val Gly Pro 
                85                  90                  95      


Ile Tyr Pro Pro Ala Ser Thr Ser Trp Met Pro Ser Gln Cys Cys Ser 
            100                 105                 110         


Ala Cys Ser His Ala Gly Ser Gln Arg Pro Arg Asn Ser Ala Glu Gly 
        115                 120                 125             


Glu Leu Leu His Gly Trp Phe Arg Trp Trp Leu His His Leu Val Arg 
    130                 135                 140                 


Asn Gln Gly His Leu Cys Ala Gly Lys Asp Ile Thr Tyr Leu Gln His 
145                 150                 155                 160 


Phe Ser Gln Cys Asn Cys Phe Ser His Ile Asn Leu Lys Leu Gln Phe 
                165                 170                 175     


Arg His Met Leu Leu Gly Cys Leu Ser Gly Ala Gln Thr Phe Arg His 
            180                 185                 190         


Phe Ser Asn Leu Ile Arg Asn His Val Met Val Ala Val Pro Pro 
        195                 200                 205         


<210>  3998
<211>  1056
<212>  PRT
<213>  homo sapiens

<400>  3998

Met Ala Cys Pro Ala Leu Gly Leu Glu Ala Leu Gln Pro Leu Gln Pro 
1               5                   10                  15      


Glu Pro Pro Pro Glu Pro Ala Phe Ser Glu Ala Gln Lys Trp Ile Glu 
            20                  25                  30          


Gln Val Thr Gly Arg Ser Phe Gly Asp Lys Asp Phe Arg Thr Gly Leu 
        35                  40                  45              


Glu Asn Gly Ile Leu Leu Cys Glu Leu Leu Asn Ala Ile Lys Pro Gly 
    50                  55                  60                  


Leu Val Lys Lys Ile Asn Arg Leu Pro Thr Pro Ile Ala Gly Leu Asp 
65                  70                  75                  80  


Asn Ile Ile Leu Phe Leu Arg Gly Cys Lys Glu Leu Gly Leu Lys Glu 
                85                  90                  95      


Ser Gln Leu Phe Asp Pro Ser Asp Leu Gln Asp Thr Ser Asn Arg Val 
            100                 105                 110         


Thr Val Lys Ser Leu Asp Tyr Ser Arg Lys Leu Lys Asn Val Leu Val 
        115                 120                 125             


Thr Ile Tyr Trp Leu Gly Lys Ala Ala Asn Ser Cys Thr Ser Tyr Ser 
    130                 135                 140                 


Gly Thr Thr Leu Asn Leu Lys Glu Phe Glu Gly Leu Leu Ala Gln Met 
145                 150                 155                 160 


Arg Lys Asp Thr Asp Asp Ile Glu Ser Pro Lys Arg Ser Ile Arg Asp 
                165                 170                 175     


Ser Gly Tyr Ile Asp Cys Trp Asp Ser Glu Arg Ser Asp Ser Leu Ser 
            180                 185                 190         


Pro Pro Arg His Gly Arg Asp Asp Ser Phe Asp Ser Leu Asp Ser Phe 
        195                 200                 205             


Gly Ser Arg Ser Arg Gln Thr Pro Ser Pro Asp Val Val Leu Arg Gly 
    210                 215                 220                 


Ser Ser Asp Gly Arg Gly Ser Asp Ser Glu Ser Asp Leu Pro His Arg 
225                 230                 235                 240 


Lys Leu Pro Asp Val Lys Lys Asp Asp Met Ser Ala Arg Arg Thr Ser 
                245                 250                 255     


His Gly Glu Pro Lys Ser Ala Val Pro Phe Asn Gln Tyr Leu Pro Asn 
            260                 265                 270         


Lys Ser Asn Gln Thr Ala Tyr Val Pro Ala Pro Leu Arg Lys Lys Lys 
        275                 280                 285             


Ala Glu Arg Glu Glu Tyr Arg Lys Ser Trp Ser Thr Ala Thr Ser Pro 
    290                 295                 300                 


Leu Gly Gly Glu Arg Pro Phe Arg Tyr Gly Pro Arg Thr Pro Val Ser 
305                 310                 315                 320 


Asp Asp Ala Glu Ser Thr Ser Met Phe Asp Met Arg Cys Glu Glu Glu 
                325                 330                 335     


Ala Ala Val Gln Pro His Ser Arg Ala Arg Gln Glu Gln Leu Gln Leu 
            340                 345                 350         


Ile Asn Asn Gln Leu Arg Glu Glu Asp Asp Lys Trp Gln Asp Asp Leu 
        355                 360                 365             


Ala Arg Trp Lys Ser Arg Arg Arg Ser Val Ser Gln Asp Leu Ile Lys 
    370                 375                 380                 


Lys Glu Glu Glu Arg Lys Lys Met Glu Lys Leu Leu Ala Gly Glu Asp 
385                 390                 395                 400 


Gly Thr Ser Glu Arg Arg Lys Ser Ile Lys Thr Tyr Arg Glu Ile Val 
                405                 410                 415     


Gln Glu Lys Glu Arg Arg Glu Arg Glu Leu His Glu Ala Tyr Lys Asn 
            420                 425                 430         


Ala Arg Ser Gln Glu Glu Ala Glu Gly Ile Leu Gln Gln Tyr Ile Glu 
        435                 440                 445             


Arg Phe Thr Ile Ser Glu Ala Val Leu Glu Arg Leu Glu Met Pro Lys 
    450                 455                 460                 


Ile Leu Glu Arg Ser His Ser Thr Glu Pro Asn Leu Ser Ser Phe Leu 
465                 470                 475                 480 


Asn Asp Pro Asn Pro Met Lys Tyr Leu Arg Gln Gln Ser Leu Pro Pro 
                485                 490                 495     


Pro Lys Phe Thr Ala Thr Val Glu Thr Thr Ile Ala Arg Ala Ser Val 
            500                 505                 510         


Leu Asp Thr Ser Met Ser Ala Gly Ser Gly Ser Pro Ser Lys Thr Val 
        515                 520                 525             


Thr Pro Lys Ala Val Pro Met Leu Thr Pro Lys Pro Tyr Ser Gln Pro 
    530                 535                 540                 


Lys Asn Ser Gln Asp Val Leu Lys Thr Phe Lys Val Asp Gly Lys Val 
545                 550                 555                 560 


Ser Val Asn Gly Glu Thr Val His Arg Glu Glu Glu Lys Glu Arg Glu 
                565                 570                 575     


Cys Pro Thr Val Ala Pro Ala His Ser Leu Thr Lys Ser Gln Met Phe 
            580                 585                 590         


Glu Gly Val Ala Arg Val His Gly Ser Pro Leu Glu Leu Lys Gln Asp 
        595                 600                 605             


Asn Gly Ser Ile Glu Ile Asn Ile Lys Lys Pro Asn Ser Val Pro Gln 
    610                 615                 620                 


Glu Leu Ala Ala Thr Thr Glu Lys Thr Glu Pro Asn Ser Gln Glu Asp 
625                 630                 635                 640 


Lys Asn Asp Gly Gly Lys Ser Arg Lys Gly Asn Ile Glu Leu Ala Ser 
                645                 650                 655     


Ser Glu Pro Gln His Phe Thr Thr Thr Val Thr Arg Cys Ser Pro Thr 
            660                 665                 670         


Val Ala Phe Val Glu Phe Pro Ser Ser Pro Gln Leu Lys Asn Asp Val 
        675                 680                 685             


Ser Glu Glu Lys Asp Gln Lys Lys Pro Glu Asn Glu Met Ser Gly Lys 
    690                 695                 700                 


Val Glu Leu Val Leu Ser Gln Lys Val Val Lys Pro Lys Ser Pro Glu 
705                 710                 715                 720 


Pro Glu Ala Thr Leu Thr Phe Pro Phe Leu Asp Lys Met Pro Glu Ala 
                725                 730                 735     


Asn Gln Leu His Leu Pro Asn Leu Asn Ser Gln Val Asp Ser Pro Ser 
            740                 745                 750         


Ser Glu Lys Ser Pro Val Met Thr Pro Phe Lys Phe Trp Ala Trp Asp 
        755                 760                 765             


Pro Glu Glu Glu Arg Arg Arg Gln Glu Lys Trp Gln Gln Glu Gln Glu 
    770                 775                 780                 


Arg Leu Leu Gln Glu Arg Tyr Gln Lys Glu Gln Asp Lys Leu Lys Glu 
785                 790                 795                 800 


Glu Trp Glu Lys Ala Gln Lys Glu Val Glu Glu Glu Glu Arg Arg Tyr 
                805                 810                 815     


Tyr Glu Glu Glu Arg Lys Ile Ile Glu Asp Thr Val Val Pro Phe Thr 
            820                 825                 830         


Val Ser Ser Ser Ser Ala Asp Gln Leu Ser Thr Ser Ser Ser Met Thr 
        835                 840                 845             


Glu Gly Ser Gly Thr Met Asn Lys Ile Asp Leu Gly Asn Cys Gln Asp 
    850                 855                 860                 


Glu Lys Gln Asp Arg Arg Trp Lys Lys Ser Phe Gln Gly Asp Asp Ser 
865                 870                 875                 880 


Asp Leu Leu Leu Lys Thr Arg Glu Ser Asp Arg Leu Glu Glu Lys Gly 
                885                 890                 895     


Ser Leu Thr Glu Gly Ala Leu Ala His Ser Gly Asn Pro Val Ser Lys 
            900                 905                 910         


Gly Val His Glu Asp His Gln Leu Asp Thr Glu Ala Gly Ala Pro His 
        915                 920                 925             


Cys Gly Thr Asn Pro Gln Leu Ala Gln Asp Pro Ser Gln Asn Gln Gln 
    930                 935                 940                 


Thr Ser Asn Pro Thr His Ser Ser Glu Asp Val Lys Pro Lys Thr Leu 
945                 950                 955                 960 


Pro Leu Asp Lys Ser Ile Asn His Gln Ile Glu Ser Pro Ser Glu Arg 
                965                 970                 975     


Arg Lys Ser Ile Ser Gly Lys Lys Leu Cys Ser Ser Cys Gly Leu Pro 
            980                 985                 990         


Leu Gly Lys Gly Ala Ala Met Ile  Ile Glu Thr Leu Asn  Leu Tyr Phe 
        995                 1000                 1005             


His Ile  Gln Cys Phe Arg Cys  Gly Ile Cys Lys Gly  Gln Leu Gly 
    1010                 1015                 1020             


Asp Ala  Val Ser Gly Thr Asp  Val Arg Ile Arg Asn  Gly Leu Leu 
    1025                 1030                 1035             


Asn Cys  Asn Asp Cys Tyr Met  Arg Ser Arg Ser Ala  Gly Gln Pro 
    1040                 1045                 1050             


Thr Thr  Leu 
    1055     


<210>  3999
<211>  505
<212>  PRT
<213>  homo sapiens

<400>  3999

Met Asp Pro Gly Asn Glu Asn Ser Ala Thr Glu Ala Ala Ala Ile Ile 
1               5                   10                  15      


Asp Leu Asp Pro Asp Phe Glu Pro Gln Ser Arg Pro Arg Ser Cys Thr 
            20                  25                  30          


Trp Pro Leu Pro Arg Pro Glu Ile Ala Asn Gln Pro Ser Glu Pro Pro 
        35                  40                  45              


Glu Val Glu Pro Asp Leu Gly Glu Lys Val His Thr Glu Gly Arg Ser 
    50                  55                  60                  


Glu Pro Ile Leu Leu Pro Ser Arg Leu Pro Glu Pro Ala Gly Gly Pro 
65                  70                  75                  80  


Gln Pro Gly Ile Leu Gly Ala Val Thr Gly Pro Arg Lys Gly Gly Ser 
                85                  90                  95      


Arg Arg Asn Ala Trp Gly Asn Gln Ser Tyr Ala Glu Leu Ile Ser Gln 
            100                 105                 110         


Ala Ile Glu Ser Ala Pro Glu Lys Arg Leu Thr Leu Ala Gln Ile Tyr 
        115                 120                 125             


Glu Trp Met Val Arg Thr Val Pro Tyr Phe Lys Asp Lys Gly Asp Ser 
    130                 135                 140                 


Asn Ser Ser Ala Gly Trp Lys Asn Ser Ile Arg His Asn Leu Ser Leu 
145                 150                 155                 160 


His Ser Lys Phe Ile Lys Val His Asn Glu Ala Thr Gly Lys Ser Ser 
                165                 170                 175     


Trp Trp Met Leu Asn Pro Glu Gly Gly Lys Ser Gly Lys Ala Pro Arg 
            180                 185                 190         


Arg Arg Ala Ala Ser Met Asp Ser Ser Ser Lys Leu Leu Arg Gly Arg 
        195                 200                 205             


Ser Lys Ala Pro Lys Lys Lys Pro Ser Val Leu Pro Ala Pro Pro Glu 
    210                 215                 220                 


Gly Ala Thr Pro Thr Ser Pro Val Gly His Phe Ala Lys Trp Ser Gly 
225                 230                 235                 240 


Ser Pro Cys Ser Arg Asn Arg Glu Glu Ala Asp Met Trp Thr Thr Phe 
                245                 250                 255     


Arg Pro Arg Ser Ser Ser Asn Ala Ser Ser Val Ser Thr Arg Leu Ser 
            260                 265                 270         


Pro Leu Arg Pro Glu Ser Glu Val Leu Ala Glu Glu Ile Pro Ala Ser 
        275                 280                 285             


Val Ser Ser Tyr Ala Gly Gly Val Pro Pro Thr Leu Asn Glu Gly Leu 
    290                 295                 300                 


Glu Leu Leu Asp Gly Leu Asn Leu Thr Ser Ser His Ser Leu Leu Ser 
305                 310                 315                 320 


Arg Ser Gly Leu Ser Gly Phe Ser Leu Gln His Pro Gly Val Thr Gly 
                325                 330                 335     


Pro Leu His Thr Tyr Ser Ser Ser Leu Phe Ser Pro Ala Glu Gly Pro 
            340                 345                 350         


Leu Ser Ala Gly Glu Gly Cys Phe Ser Ser Ser Gln Ala Leu Glu Ala 
        355                 360                 365             


Leu Leu Thr Ser Asp Thr Pro Pro Pro Pro Ala Asp Val Leu Met Thr 
    370                 375                 380                 


Gln Val Asp Pro Ile Leu Ser Gln Ala Pro Thr Leu Leu Leu Leu Gly 
385                 390                 395                 400 


Gly Leu Pro Ser Ser Ser Lys Leu Ala Thr Gly Val Gly Leu Cys Pro 
                405                 410                 415     


Lys Pro Leu Glu Ala Pro Gly Pro Ser Ser Leu Val Pro Thr Leu Ser 
            420                 425                 430         


Met Ile Ala Pro Pro Pro Val Met Ala Ser Ala Pro Ile Pro Lys Ala 
        435                 440                 445             


Leu Gly Thr Pro Val Leu Thr Pro Pro Thr Glu Ala Ala Ser Gln Asp 
    450                 455                 460                 


Arg Met Pro Gln Asp Leu Asp Leu Asp Met Tyr Met Glu Asn Leu Glu 
465                 470                 475                 480 


Cys Asp Met Asp Asn Ile Ile Ser Asp Leu Met Asp Glu Gly Glu Gly 
                485                 490                 495     


Leu Asp Phe Asn Phe Glu Pro Asp Pro 
            500                 505 


<210>  4000
<211>  183
<212>  PRT
<213>  homo sapiens

<400>  4000

Met Arg Ala Ala Tyr Leu Phe Leu Leu Phe Leu Pro Ala Gly Leu Leu 
1               5                   10                  15      


Ala Gln Gly Gln Tyr Asp Leu Asp Pro Leu Pro Pro Phe Pro Asp His 
            20                  25                  30          


Val Gln Tyr Thr His Tyr Ser Asp Gln Ile Asp Asn Pro Asp Tyr Tyr 
        35                  40                  45              


Asp Tyr Gln Glu Val Thr Pro Arg Pro Ser Glu Glu Gln Phe Gln Phe 
    50                  55                  60                  


Gln Ser Gln Gln Gln Val Gln Gln Glu Val Ile Pro Ala Pro Thr Pro 
65                  70                  75                  80  


Glu Pro Gly Asn Ala Glu Leu Glu Pro Thr Glu Pro Gly Pro Leu Asp 
                85                  90                  95      


Cys Arg Glu Glu Gln Tyr Pro Cys Thr Arg Leu Tyr Ser Ile His Arg 
            100                 105                 110         


Pro Cys Lys Gln Cys Leu Asn Glu Val Cys Phe Tyr Ser Leu Arg Arg 
        115                 120                 125             


Val Tyr Val Ile Asn Lys Glu Ile Cys Val Arg Thr Val Cys Ala His 
    130                 135                 140                 


Glu Glu Leu Leu Arg Ala Asp Leu Cys Arg Asp Lys Phe Ser Lys Cys 
145                 150                 155                 160 


Gly Val Met Ala Ser Ser Gly Leu Cys Gln Ser Val Ala Ala Ser Cys 
                165                 170                 175     


Ala Arg Ser Cys Gly Ser Cys 
            180             


<210>  4001
<211>  332
<212>  PRT
<213>  homo sapiens

<400>  4001

Met Val Phe Arg Ser Pro Leu Asp Leu Tyr Ser Ser His Phe Leu Leu 
1               5                   10                  15      


Pro Asn Phe Ala Asp Ser His His Arg Ser Ile Leu Leu Ala Ser Ser 
            20                  25                  30          


Gly Gly Gly Asn Gly Ala Gly Gly Gly Gly Gly Ala Gly Gly Gly Ser 
        35                  40                  45              


Gly Gly Gly Asn Gly Ala Gly Gly Gly Gly Ala Gly Gly Ala Gly Gly 
    50                  55                  60                  


Gly Gly Gly Gly Gly Ser Arg Ala Pro Pro Glu Glu Leu Ser Met Phe 
65                  70                  75                  80  


Gln Leu Pro Thr Leu Asn Phe Ser Pro Glu Gln Val Ala Ser Val Cys 
                85                  90                  95      


Glu Thr Leu Glu Glu Thr Gly Asp Ile Glu Arg Leu Gly Arg Phe Leu 
            100                 105                 110         


Trp Ser Leu Pro Val Ala Pro Gly Ala Cys Glu Ala Ile Asn Lys His 
        115                 120                 125             


Glu Ser Ile Leu Arg Ala Arg Ala Val Val Ala Phe His Thr Gly Asn 
    130                 135                 140                 


Phe Arg Asp Leu Tyr His Ile Leu Glu Asn His Lys Phe Thr Lys Glu 
145                 150                 155                 160 


Ser His Gly Lys Leu Gln Ala Met Trp Leu Glu Ala His Tyr Gln Glu 
                165                 170                 175     


Ala Glu Lys Leu Arg Gly Arg Pro Leu Gly Pro Val Asp Lys Tyr Arg 
            180                 185                 190         


Val Arg Lys Lys Phe Pro Leu Pro Arg Thr Ile Trp Asp Gly Glu Gln 
        195                 200                 205             


Lys Thr His Cys Phe Lys Glu Arg Thr Arg Ser Leu Leu Arg Glu Trp 
    210                 215                 220                 


Tyr Leu Gln Asp Pro Tyr Pro Asn Pro Ser Lys Lys Arg Glu Leu Ala 
225                 230                 235                 240 


Gln Ala Thr Gly Leu Thr Pro Thr Gln Val Gly Asn Trp Phe Lys Asn 
                245                 250                 255     


Arg Arg Gln Arg Asp Arg Ala Ala Ala Ala Lys Asn Arg Leu Gln His 
            260                 265                 270         


Gln Ala Ile Gly Pro Ser Gly Met Arg Ser Leu Ala Glu Pro Gly Cys 
        275                 280                 285             


Pro Thr His Gly Ser Ala Glu Ser Pro Ser Thr Ala Ala Ser Pro Thr 
    290                 295                 300                 


Thr Ser Val Ser Ser Leu Thr Glu Arg Ala Asp Thr Gly Thr Ser Ile 
305                 310                 315                 320 


Leu Ser Val Thr Ser Ser Asp Ser Glu Cys Asp Val 
                325                 330         


<210>  4002
<211>  1649
<212>  PRT
<213>  homo sapiens

<400>  4002

Met Ala Gly Gly Arg Gly Ala Pro Gly Arg Gly Arg Asp Glu Pro Pro 
1               5                   10                  15      


Glu Ser Tyr Pro Gln Arg Gln Asp His Glu Leu Gln Ala Leu Glu Ala 
            20                  25                  30          


Ile Tyr Gly Ala Asp Phe Gln Asp Leu Arg Pro Asp Ala Cys Gly Pro 
        35                  40                  45              


Val Lys Glu Pro Pro Glu Ile Asn Leu Val Leu Tyr Pro Gln Gly Leu 
    50                  55                  60                  


Thr Gly Glu Glu Val Tyr Val Lys Val Asp Leu Arg Val Lys Cys Pro 
65                  70                  75                  80  


Pro Thr Tyr Pro Asp Val Val Pro Glu Ile Glu Leu Lys Asn Ala Lys 
                85                  90                  95      


Gly Leu Ser Asn Glu Ser Val Asn Leu Leu Lys Ser Arg Leu Glu Glu 
            100                 105                 110         


Leu Ala Lys Lys His Cys Gly Glu Val Met Ile Phe Glu Leu Ala Tyr 
        115                 120                 125             


His Val Gln Ser Phe Leu Ser Glu His Asn Lys Pro Pro Pro Lys Ser 
    130                 135                 140                 


Phe His Glu Glu Met Leu Glu Arg Arg Ala Gln Glu Glu Gln Gln Arg 
145                 150                 155                 160 


Leu Leu Glu Ala Lys Arg Lys Glu Glu Gln Glu Gln Arg Glu Ile Leu 
                165                 170                 175     


His Glu Ile Gln Arg Arg Lys Glu Glu Ile Lys Glu Glu Lys Lys Arg 
            180                 185                 190         


Lys Glu Met Ala Lys Gln Glu Arg Leu Glu Ile Ala Ser Leu Ser Asn 
        195                 200                 205             


Gln Asp His Thr Ser Lys Lys Asp Pro Gly Gly His Arg Thr Ala Ala 
    210                 215                 220                 


Ile Leu His Gly Gly Ser Pro Asp Phe Val Gly Asn Gly Lys His Arg 
225                 230                 235                 240 


Ala Asn Ser Ser Gly Arg Ser Arg Arg Glu Arg Gln Tyr Ser Val Cys 
                245                 250                 255     


Asn Ser Glu Asp Ser Pro Gly Ser Cys Glu Ile Leu Tyr Phe Asn Met 
            260                 265                 270         


Gly Ser Pro Asp Gln Leu Met Val His Lys Gly Lys Cys Ile Gly Ser 
        275                 280                 285             


Asp Glu Gln Leu Gly Lys Leu Val Tyr Asn Ala Leu Glu Thr Ala Thr 
    290                 295                 300                 


Gly Gly Phe Val Leu Leu Tyr Glu Trp Val Leu Gln Trp Gln Lys Lys 
305                 310                 315                 320 


Met Gly Pro Phe Leu Thr Ser Gln Glu Lys Glu Lys Ile Asp Lys Cys 
                325                 330                 335     


Lys Lys Gln Ile Gln Gly Thr Glu Thr Glu Phe Asn Ser Leu Val Lys 
            340                 345                 350         


Leu Ser His Pro Asn Val Val Arg Tyr Leu Ala Met Asn Leu Lys Glu 
        355                 360                 365             


Gln Asp Asp Ser Ile Val Val Asp Ile Leu Val Glu His Ile Ser Gly 
    370                 375                 380                 


Val Ser Leu Ala Ala His Leu Ser His Ser Gly Pro Ile Pro Val His 
385                 390                 395                 400 


Gln Leu Arg Arg Tyr Thr Ala Gln Leu Leu Ser Gly Leu Asp Tyr Leu 
                405                 410                 415     


His Ser Asn Ser Val Val His Lys Val Leu Ser Ala Ser Asn Val Leu 
            420                 425                 430         


Val Asp Ala Glu Gly Thr Val Lys Ile Thr Asp Tyr Ser Ile Ser Lys 
        435                 440                 445             


Arg Leu Ala Asp Ile Cys Lys Glu Asp Val Phe Glu Gln Thr Arg Val 
    450                 455                 460                 


Arg Phe Ser Asp Asn Ala Leu Pro Tyr Lys Thr Gly Lys Lys Gly Asp 
465                 470                 475                 480 


Val Trp Arg Leu Gly Leu Leu Leu Leu Ser Leu Ser Gln Gly Gln Glu 
                485                 490                 495     


Cys Gly Glu Tyr Pro Val Thr Ile Pro Ser Asp Leu Pro Ala Asp Phe 
            500                 505                 510         


Gln Asp Phe Leu Lys Lys Cys Val Cys Leu Asp Asp Lys Glu Arg Trp 
        515                 520                 525             


Ser Pro Gln Gln Leu Leu Lys His Ser Phe Ile Asn Pro Gln Pro Lys 
    530                 535                 540                 


Met Pro Leu Val Glu Gln Ser Pro Glu Asp Ser Glu Gly Gln Asp Tyr 
545                 550                 555                 560 


Val Glu Thr Val Ile Pro Ser Asn Arg Leu Pro Ser Ala Ala Phe Phe 
                565                 570                 575     


Ser Glu Thr Gln Arg Gln Phe Ser Arg Tyr Phe Ile Glu Phe Glu Glu 
            580                 585                 590         


Leu Gln Leu Leu Gly Lys Gly Ala Phe Gly Ala Val Ile Lys Val Gln 
        595                 600                 605             


Asn Lys Leu Asp Gly Cys Cys Tyr Ala Val Lys Arg Ile Pro Ile Asn 
    610                 615                 620                 


Pro Ala Ser Arg Gln Phe Arg Arg Ile Lys Gly Glu Val Thr Leu Leu 
625                 630                 635                 640 


Ser Arg Leu His His Glu Asn Ile Val Arg Tyr Tyr Asn Ala Trp Ile 
                645                 650                 655     


Glu Arg His Glu Arg Pro Ala Gly Pro Gly Thr Pro Pro Pro Asp Ser 
            660                 665                 670         


Gly Pro Leu Ala Lys Asp Asp Arg Ala Ala Arg Gly Gln Pro Ala Ser 
        675                 680                 685             


Asp Thr Asp Gly Leu Asp Ser Val Glu Ala Ala Ala Pro Pro Pro Ile 
    690                 695                 700                 


Leu Ser Ser Ser Val Glu Trp Ser Thr Ser Gly Glu Arg Ser Ala Ser 
705                 710                 715                 720 


Ala Arg Phe Pro Ala Thr Gly Pro Gly Ser Ser Asp Asp Glu Asp Asp 
                725                 730                 735     


Asp Glu Asp Glu His Gly Gly Val Phe Ser Gln Ser Phe Leu Pro Ala 
            740                 745                 750         


Ser Asp Ser Glu Ser Asp Ile Ile Phe Asp Asn Glu Asp Glu Asn Ser 
        755                 760                 765             


Lys Ser Gln Asn Gln Asp Glu Asp Cys Asn Glu Lys Asn Gly Cys His 
    770                 775                 780                 


Glu Ser Glu Pro Ser Val Thr Thr Glu Ala Val His Tyr Leu Tyr Ile 
785                 790                 795                 800 


Gln Met Glu Tyr Cys Glu Lys Ser Thr Leu Arg Asp Thr Ile Asp Gln 
                805                 810                 815     


Gly Leu Tyr Arg Asp Thr Val Arg Leu Trp Arg Leu Phe Arg Glu Ile 
            820                 825                 830         


Leu Asp Gly Leu Ala Tyr Ile His Glu Lys Gly Met Ile His Arg Asp 
        835                 840                 845             


Leu Lys Pro Val Asn Ile Phe Leu Asp Ser Asp Asp His Val Lys Ile 
    850                 855                 860                 


Gly Asp Phe Gly Leu Ala Thr Asp His Leu Ala Phe Ser Ala Asp Ser 
865                 870                 875                 880 


Lys Gln Asp Asp Gln Thr Gly Asp Leu Ile Lys Ser Asp Pro Ser Gly 
                885                 890                 895     


His Leu Thr Gly Met Val Gly Thr Ala Leu Tyr Val Ser Pro Glu Val 
            900                 905                 910         


Gln Gly Ser Thr Lys Ser Ala Tyr Asn Gln Lys Val Asp Leu Phe Ser 
        915                 920                 925             


Leu Gly Ile Ile Phe Phe Glu Met Ser Tyr His Pro Met Val Thr Ala 
    930                 935                 940                 


Ser Glu Arg Ile Phe Val Leu Asn Gln Leu Arg Asp Pro Thr Ser Pro 
945                 950                 955                 960 


Lys Phe Pro Glu Asp Phe Asp Asp Gly Glu His Ala Lys Gln Lys Ser 
                965                 970                 975     


Val Ile Ser Trp Leu Leu Asn His Asp Pro Ala Lys Arg Pro Thr Ala 
            980                 985                 990         


Thr Glu Leu Leu Lys Ser Glu Leu  Leu Pro Pro Pro Gln  Met Glu Glu 
        995                 1000                 1005             


Ser Glu  Leu His Glu Val Leu  His His Thr Leu Thr  Asn Val Asp 
    1010                 1015                 1020             


Gly Lys  Ala Tyr Arg Thr Met  Met Ala Gln Ile Phe  Ser Gln Arg 
    1025                 1030                 1035             


Ile Ser  Pro Ala Ile Asp Tyr  Thr Tyr Asp Ser Asp  Ile Leu Lys 
    1040                 1045                 1050             


Gly Asn  Phe Ser Ile Arg Thr  Ala Lys Met Gln Gln  His Val Cys 
    1055                 1060                 1065             


Glu Thr  Ile Ile Arg Ile Phe  Lys Arg His Gly Ala  Val Gln Leu 
    1070                 1075                 1080             


Cys Thr  Pro Leu Leu Leu Pro  Arg Asn Arg Gln Ile  Tyr Glu His 
    1085                 1090                 1095             


Asn Glu  Ala Ala Leu Phe Met  Asp His Ser Gly Met  Leu Val Met 
    1100                 1105                 1110             


Leu Pro  Phe Asp Leu Arg Ile  Pro Phe Ala Arg Tyr  Val Ala Arg 
    1115                 1120                 1125             


Asn Asn  Ile Leu Asn Leu Lys  Arg Tyr Cys Ile Glu  Arg Val Phe 
    1130                 1135                 1140             


Arg Pro  Arg Lys Leu Asp Arg  Phe His Pro Lys Glu  Leu Leu Glu 
    1145                 1150                 1155             


Cys Ala  Phe Asp Ile Val Thr  Ser Thr Thr Asn Ser  Phe Leu Pro 
    1160                 1165                 1170             


Thr Ala  Glu Ile Ile Tyr Thr  Ile Tyr Glu Ile Ile  Gln Glu Phe 
    1175                 1180                 1185             


Pro Ala  Leu Gln Glu Arg Asn  Tyr Ser Ile Tyr Leu  Asn His Thr 
    1190                 1195                 1200             


Met Leu  Leu Lys Ala Ile Leu  Leu His Cys Gly Ile  Pro Glu Asp 
    1205                 1210                 1215             


Lys Leu  Ser Gln Val Tyr Ile  Ile Leu Tyr Asp Ala  Val Thr Glu 
    1220                 1225                 1230             


Lys Leu  Thr Arg Arg Glu Val  Glu Ala Lys Phe Cys  Asn Leu Ser 
    1235                 1240                 1245             


Leu Ser  Ser Asn Ser Leu Cys  Arg Leu Tyr Lys Phe  Ile Glu Gln 
    1250                 1255                 1260             


Lys Gly  Asp Leu Gln Asp Leu  Met Pro Thr Ile Asn  Ser Leu Ile 
    1265                 1270                 1275             


Lys Gln  Lys Thr Gly Ile Ala  Gln Leu Val Lys Tyr  Gly Leu Lys 
    1280                 1285                 1290             


Asp Leu  Glu Glu Val Val Gly  Leu Leu Lys Lys Leu  Gly Ile Lys 
    1295                 1300                 1305             


Leu Gln  Val Leu Ile Asn Leu  Gly Leu Val Tyr Lys  Val Gln Gln 
    1310                 1315                 1320             


His Asn  Gly Ile Ile Phe Gln  Phe Val Ala Phe Ile  Lys Arg Arg 
    1325                 1330                 1335             


Gln Arg  Ala Val Pro Glu Ile  Leu Ala Ala Gly Gly  Arg Tyr Asp 
    1340                 1345                 1350             


Leu Leu  Ile Pro Gln Phe Arg  Gly Pro Gln Ala Leu  Gly Pro Val 
    1355                 1360                 1365             


Pro Thr  Ala Ile Gly Val Ser  Ile Ala Ile Asp Lys  Ile Ser Ala 
    1370                 1375                 1380             


Ala Val  Leu Asn Met Glu Glu  Ser Val Thr Ile Ser  Ser Cys Asp 
    1385                 1390                 1395             


Leu Leu  Val Val Ser Val Gly  Gln Met Ser Met Ser  Arg Ala Ile 
    1400                 1405                 1410             


Asn Leu  Thr Gln Lys Leu Trp  Thr Ala Gly Ile Thr  Ala Glu Ile 
    1415                 1420                 1425             


Met Tyr  Asp Trp Ser Gln Ser  Gln Glu Glu Leu Gln  Glu Tyr Cys 
    1430                 1435                 1440             


Arg His  His Glu Ile Thr Tyr  Val Ala Leu Val Ser  Asp Lys Glu 
    1445                 1450                 1455             


Gly Ser  His Val Lys Val Lys  Ser Phe Glu Lys Glu  Arg Gln Thr 
    1460                 1465                 1470             


Glu Lys  Arg Val Leu Glu Thr  Glu Leu Val Asp His  Val Leu Gln 
    1475                 1480                 1485             


Lys Leu  Arg Thr Lys Val Thr  Asp Glu Arg Asn Gly  Arg Glu Ala 
    1490                 1495                 1500             


Ser Asp  Asn Leu Ala Val Gln  Asn Leu Lys Gly Ser  Phe Ser Asn 
    1505                 1510                 1515             


Ala Ser  Gly Leu Phe Glu Ile  His Gly Ala Thr Val  Val Pro Ile 
    1520                 1525                 1530             


Val Ser  Val Leu Ala Pro Glu  Lys Leu Ser Ala Ser  Thr Arg Arg 
    1535                 1540                 1545             


Arg Tyr  Glu Thr Gln Val Gln  Thr Arg Leu Gln Thr  Ser Leu Ala 
    1550                 1555                 1560             


Asn Leu  His Gln Lys Ser Ser  Glu Ile Glu Ile Leu  Ala Val Asp 
    1565                 1570                 1575             


Leu Pro  Lys Glu Thr Ile Leu  Gln Phe Leu Ser Leu  Glu Trp Asp 
    1580                 1585                 1590             


Ala Asp  Glu Gln Ala Phe Asn  Thr Thr Val Lys Gln  Leu Leu Ser 
    1595                 1600                 1605             


Arg Leu  Pro Lys Gln Arg Tyr  Leu Lys Leu Val Cys  Asp Glu Ile 
    1610                 1615                 1620             


Tyr Asn  Ile Lys Val Glu Lys  Lys Val Ser Val Leu  Phe Leu Tyr 
    1625                 1630                 1635             


Ser Tyr  Arg Asp Asp Tyr Tyr  Arg Ile Leu Phe 
    1640                 1645                 


<210>  4003
<211>  332
<212>  PRT
<213>  homo sapiens

<400>  4003

Met Gly Ile Val Gln Ile Cys Lys Gly Glu Tyr Phe Trp Leu Glu Pro 
1               5                   10                  15      


Lys Asn Ala Phe Glu Asn Phe Gln Glu Pro Asp Ile Gly Leu Val Ala 
            20                  25                  30          


Leu Ala Phe Leu Gln Gly Ser Phe Ala Tyr Gly Gly Trp Asn Phe Leu 
        35                  40                  45              


Asn Tyr Val Thr Glu Glu Leu Val Asp Pro Tyr Lys Asn Leu Pro Arg 
    50                  55                  60                  


Ala Ile Phe Ile Ser Ile Pro Leu Val Thr Phe Val Tyr Val Phe Ala 
65                  70                  75                  80  


Asn Val Ala Tyr Val Thr Ala Met Ser Pro Gln Glu Leu Leu Ala Ser 
                85                  90                  95      


Asn Ala Val Ala Val Thr Phe Gly Glu Lys Leu Leu Gly Val Met Ala 
            100                 105                 110         


Trp Ile Met Pro Ile Ser Val Ala Leu Ser Thr Phe Gly Gly Val Asn 
        115                 120                 125             


Gly Ser Leu Phe Thr Ser Ser Arg Leu Phe Phe Ala Gly Ala Arg Glu 
    130                 135                 140                 


Gly His Leu Pro Ser Val Leu Ala Met Ile His Val Lys Arg Cys Thr 
145                 150                 155                 160 


Pro Ile Pro Ala Leu Leu Phe Thr Cys Ile Ser Thr Leu Leu Met Leu 
                165                 170                 175     


Val Thr Ser Asp Met Tyr Thr Leu Ile Asn Tyr Val Gly Phe Ile Asn 
            180                 185                 190         


Tyr Leu Phe Tyr Gly Val Thr Val Ala Gly Gln Ile Val Leu Arg Trp 
        195                 200                 205             


Lys Lys Pro Asp Ile Pro Arg Pro Ile Lys Ile Asn Leu Leu Phe Pro 
    210                 215                 220                 


Ile Ile Tyr Leu Leu Phe Trp Ala Phe Leu Leu Val Phe Ser Leu Trp 
225                 230                 235                 240 


Ser Glu Pro Val Val Cys Gly Ile Gly Leu Ala Ile Met Leu Thr Gly 
                245                 250                 255     


Val Pro Val Tyr Phe Leu Gly Val Tyr Trp Gln His Lys Pro Lys Cys 
            260                 265                 270         


Phe Ser Asp Phe Ile Glu Leu Leu Thr Leu Val Ser Gln Lys Met Cys 
        275                 280                 285             


Val Val Val Tyr Pro Glu Val Glu Arg Gly Ser Gly Thr Glu Glu Ala 
    290                 295                 300                 


Asn Glu Asp Met Glu Glu Gln Gln Gln Pro Met Tyr Gln Pro Thr Pro 
305                 310                 315                 320 


Thr Lys Asp Lys Asp Val Ala Gly Gln Pro Gln Pro 
                325                 330         


<210>  4004
<211>  1828
<212>  PRT
<213>  homo sapiens

<400>  4004

Met Ala Ala Ser Glu Leu Tyr Thr Lys Phe Ala Arg Val Trp Ile Pro 
1               5                   10                  15      


Asp Pro Glu Glu Val Trp Lys Ser Ala Glu Leu Leu Lys Asp Tyr Lys 
            20                  25                  30          


Pro Gly Asp Lys Val Leu Leu Leu His Leu Glu Glu Gly Lys Asp Leu 
        35                  40                  45              


Glu Tyr His Leu Asp Pro Lys Thr Lys Glu Leu Pro His Leu Arg Asn 
    50                  55                  60                  


Pro Asp Ile Leu Val Gly Glu Asn Asp Leu Thr Ala Leu Ser Tyr Leu 
65                  70                  75                  80  


His Glu Pro Ala Val Leu His Asn Leu Arg Val Arg Phe Ile Asp Ser 
                85                  90                  95      


Lys Leu Ile Tyr Thr Tyr Cys Gly Ile Val Leu Val Ala Ile Asn Pro 
            100                 105                 110         


Tyr Glu Gln Leu Pro Ile Tyr Gly Glu Asp Ile Ile Asn Ala Tyr Ser 
        115                 120                 125             


Gly Gln Asn Met Gly Asp Met Asp Pro His Ile Phe Ala Val Ala Glu 
    130                 135                 140                 


Glu Ala Tyr Lys Gln Met Ala Arg Asp Glu Arg Asn Gln Ser Ile Ile 
145                 150                 155                 160 


Val Ser Gly Glu Ser Gly Ala Gly Lys Thr Val Ser Ala Lys Tyr Ala 
                165                 170                 175     


Met Arg Tyr Phe Ala Thr Val Ser Gly Ser Ala Ser Glu Ala Asn Val 
            180                 185                 190         


Glu Glu Lys Val Leu Ala Ser Asn Pro Ile Met Glu Ser Ile Gly Asn 
        195                 200                 205             


Ala Lys Thr Thr Arg Asn Asp Asn Ser Ser Arg Phe Gly Lys Tyr Ile 
    210                 215                 220                 


Glu Ile Gly Phe Asp Lys Arg Tyr Arg Ile Ile Gly Ala Asn Met Arg 
225                 230                 235                 240 


Thr Tyr Leu Leu Glu Lys Ser Arg Val Val Phe Gln Ala Glu Glu Glu 
                245                 250                 255     


Arg Asn Tyr His Ile Phe Tyr Gln Leu Cys Ala Ser Ala Lys Leu Pro 
            260                 265                 270         


Glu Phe Lys Met Leu Arg Leu Gly Asn Ala Asp Asn Phe Asn Tyr Thr 
        275                 280                 285             


Lys Gln Gly Gly Ser Pro Val Ile Glu Gly Val Asp Asp Ala Lys Glu 
    290                 295                 300                 


Met Ala His Thr Arg Gln Ala Cys Thr Leu Leu Gly Ile Ser Glu Ser 
305                 310                 315                 320 


His Gln Met Gly Ile Phe Arg Ile Leu Ala Gly Ile Leu His Leu Gly 
                325                 330                 335     


Asn Val Gly Phe Thr Ser Arg Asp Ala Asp Ser Cys Thr Ile Pro Pro 
            340                 345                 350         


Lys His Glu Pro Leu Cys Ile Phe Cys Asp Leu Met Gly Val Asp Tyr 
        355                 360                 365             


Glu Glu Met Cys His Trp Leu Cys His Arg Lys Leu Ala Thr Ala Thr 
    370                 375                 380                 


Glu Thr Tyr Ile Lys Pro Ile Ser Lys Leu Gln Ala Thr Asn Ala Arg 
385                 390                 395                 400 


Asp Ala Leu Ala Lys His Ile Tyr Ala Lys Leu Phe Asn Trp Ile Val 
                405                 410                 415     


Asp Asn Val Asn Gln Ala Leu His Ser Ala Val Lys Gln His Ser Phe 
            420                 425                 430         


Ile Gly Val Leu Asp Ile Tyr Gly Phe Glu Thr Phe Glu Ile Asn Ser 
        435                 440                 445             


Phe Glu Gln Phe Cys Ile Asn Tyr Ala Asn Glu Lys Leu Gln Gln Gln 
    450                 455                 460                 


Phe Asn Met His Val Phe Lys Leu Glu Gln Glu Glu Tyr Met Lys Glu 
465                 470                 475                 480 


Gln Ile Pro Trp Thr Leu Ile Asp Phe Tyr Asp Asn Gln Pro Cys Ile 
                485                 490                 495     


Asn Leu Ile Glu Ser Lys Leu Gly Ile Leu Asp Leu Leu Asp Glu Glu 
            500                 505                 510         


Cys Lys Met Pro Lys Gly Thr Asp Asp Thr Trp Ala Gln Lys Leu Tyr 
        515                 520                 525             


Asn Thr His Leu Asn Lys Cys Ala Leu Phe Glu Lys Pro Arg Leu Ser 
    530                 535                 540                 


Asn Lys Ala Phe Ile Ile Gln His Phe Ala Asp Lys Val Glu Tyr Gln 
545                 550                 555                 560 


Cys Glu Gly Phe Leu Glu Lys Asn Lys Asp Thr Val Phe Glu Glu Gln 
                565                 570                 575     


Ile Lys Val Leu Lys Ser Ser Lys Phe Lys Met Leu Pro Glu Leu Phe 
            580                 585                 590         


Gln Asp Asp Glu Lys Ala Ile Ser Pro Thr Ser Ala Thr Ser Ser Gly 
        595                 600                 605             


Arg Thr Pro Leu Thr Arg Thr Pro Ala Lys Pro Thr Lys Gly Arg Pro 
    610                 615                 620                 


Gly Gln Met Ala Lys Glu His Lys Lys Thr Val Gly His Gln Phe Arg 
625                 630                 635                 640 


Asn Ser Leu His Leu Leu Met Glu Thr Leu Asn Ala Thr Thr Pro His 
                645                 650                 655     


Tyr Val Arg Cys Ile Lys Pro Asn Asp Phe Lys Phe Pro Phe Thr Phe 
            660                 665                 670         


Asp Glu Lys Arg Ala Val Gln Gln Leu Arg Ala Cys Gly Val Leu Glu 
        675                 680                 685             


Thr Ile Arg Ile Ser Ala Ala Gly Phe Pro Ser Arg Trp Thr Tyr Gln 
    690                 695                 700                 


Glu Phe Phe Ser Arg Tyr Arg Val Leu Met Lys Gln Lys Asp Val Leu 
705                 710                 715                 720 


Ser Asp Arg Lys Gln Thr Cys Lys Asn Val Leu Glu Lys Leu Ile Leu 
                725                 730                 735     


Asp Lys Asp Lys Tyr Gln Phe Gly Lys Thr Lys Ile Phe Phe Arg Ala 
            740                 745                 750         


Gly Gln Val Ala Tyr Leu Glu Lys Leu Arg Ala Asp Lys Leu Arg Ala 
        755                 760                 765             


Ala Cys Ile Arg Ile Gln Lys Thr Ile Arg Gly Trp Leu Leu Arg Lys 
    770                 775                 780                 


Lys Tyr Leu Arg Met Arg Lys Ala Ala Ile Thr Met Gln Arg Tyr Val 
785                 790                 795                 800 


Arg Gly Tyr Gln Ala Arg Cys Tyr Ala Lys Phe Leu Arg Arg Thr Lys 
                805                 810                 815     


Ala Ala Thr Ile Ile Gln Lys Tyr Trp Arg Met Tyr Val Val Arg Arg 
            820                 825                 830         


Arg Tyr Lys Ile Arg Arg Ala Ala Thr Ile Val Leu Gln Ser Tyr Leu 
        835                 840                 845             


Arg Gly Phe Leu Ala Arg Asn Arg Tyr Arg Lys Ile Leu Arg Glu His 
    850                 855                 860                 


Lys Ala Val Ile Ile Gln Lys Arg Val Arg Gly Trp Leu Ala Arg Thr 
865                 870                 875                 880 


His Tyr Lys Arg Ser Met His Ala Ile Ile Tyr Leu Gln Cys Cys Phe 
                885                 890                 895     


Arg Arg Met Met Ala Lys Arg Glu Leu Lys Lys Leu Lys Ile Glu Ala 
            900                 905                 910         


Arg Ser Val Glu Arg Tyr Lys Lys Leu His Ile Gly Met Glu Asn Lys 
        915                 920                 925             


Ile Met Gln Leu Gln Arg Lys Val Asp Glu Gln Asn Lys Asp Tyr Lys 
    930                 935                 940                 


Cys Leu Val Glu Lys Leu Thr Asn Leu Glu Gly Ile Tyr Asn Ser Glu 
945                 950                 955                 960 


Thr Glu Lys Leu Arg Ser Asp Leu Glu Arg Leu Gln Leu Ser Glu Glu 
                965                 970                 975     


Glu Ala Lys Val Ala Thr Gly Arg Val Leu Ser Leu Gln Glu Glu Ile 
            980                 985                 990         


Ala Lys Leu Arg Lys Asp Leu Glu  Gln Thr Arg Ser Glu  Lys Lys Cys 
        995                 1000                 1005             


Ile Glu  Glu His Ala Asp Arg  Tyr Lys Gln Glu Thr  Glu Gln Leu 
    1010                 1015                 1020             


Val Ser  Asn Leu Lys Glu Glu  Asn Thr Leu Leu Lys  Gln Glu Lys 
    1025                 1030                 1035             


Glu Ala  Leu Asn His Arg Ile  Val Gln Gln Ala Lys  Glu Met Thr 
    1040                 1045                 1050             


Glu Thr  Met Glu Lys Lys Leu  Val Glu Glu Thr Lys  Gln Leu Glu 
    1055                 1060                 1065             


Leu Asp  Leu Asn Asp Glu Arg  Leu Arg Tyr Gln Asn  Leu Leu Asn 
    1070                 1075                 1080             


Glu Phe  Ser Arg Leu Glu Glu  Arg Tyr Asp Asp Leu  Lys Glu Glu 
    1085                 1090                 1095             


Met Thr  Leu Met Val His Val  Pro Lys Pro Gly His  Lys Arg Thr 
    1100                 1105                 1110             


Asp Ser  Thr His Ser Ser Asn  Glu Ser Glu Tyr Ile  Phe Ser Ser 
    1115                 1120                 1125             


Glu Ile  Ala Glu Met Glu Asp  Ile Pro Ser Arg Thr  Glu Glu Pro 
    1130                 1135                 1140             


Ser Glu  Lys Lys Val Pro Leu  Asp Met Ser Leu Phe  Leu Lys Leu 
    1145                 1150                 1155             


Gln Lys  Arg Val Thr Glu Leu  Glu Gln Glu Lys Gln  Val Met Gln 
    1160                 1165                 1170             


Asp Glu  Leu Asp Arg Lys Glu  Glu Gln Val Leu Arg  Ser Lys Ala 
    1175                 1180                 1185             


Lys Glu  Glu Glu Arg Pro Gln  Ile Arg Gly Ala Glu  Leu Glu Tyr 
    1190                 1195                 1200             


Glu Ser  Leu Lys Arg Gln Glu  Leu Glu Ser Glu Asn  Lys Lys Leu 
    1205                 1210                 1215             


Lys Asn  Glu Leu Asn Glu Leu  Arg Lys Ala Leu Ser  Glu Lys Ser 
    1220                 1225                 1230             


Ala Pro  Glu Val Thr Ala Pro  Gly Ala Pro Ala Tyr  Arg Val Leu 
    1235                 1240                 1245             


Met Glu  Gln Leu Thr Ser Val  Ser Glu Glu Leu Asp  Val Arg Lys 
    1250                 1255                 1260             


Glu Glu  Val Leu Ile Leu Arg  Ser Gln Leu Val Ser  Gln Lys Glu 
    1265                 1270                 1275             


Ala Ile  Gln Pro Lys Asp Asp  Lys Asn Thr Met Thr  Asp Ser Thr 
    1280                 1285                 1290             


Ile Leu  Leu Glu Asp Val Gln  Lys Met Lys Asp Lys  Gly Glu Ile 
    1295                 1300                 1305             


Ala Gln  Ala Tyr Ile Gly Leu  Lys Glu Thr Asn Arg  Leu Leu Glu 
    1310                 1315                 1320             


Ser Gln  Leu Gln Ser Gln Lys  Arg Ser His Glu Asn  Glu Ala Glu 
    1325                 1330                 1335             


Ala Leu  Arg Gly Glu Ile Gln  Ser Leu Lys Glu Glu  Asn Asn Arg 
    1340                 1345                 1350             


Gln Gln  Gln Leu Leu Ala Gln  Asn Leu Gln Leu Pro  Pro Glu Ala 
    1355                 1360                 1365             


Arg Ile  Glu Ala Ser Leu Gln  His Glu Ile Thr Arg  Leu Thr Asn 
    1370                 1375                 1380             


Glu Asn  Leu Asp Leu Met Glu  Gln Leu Glu Lys Gln  Asp Lys Thr 
    1385                 1390                 1395             


Val Arg  Lys Leu Lys Lys Gln  Leu Lys Val Phe Ala  Lys Lys Ile 
    1400                 1405                 1410             


Gly Glu  Leu Glu Val Gly Gln  Met Glu Asn Ile Ser  Pro Gly Gln 
    1415                 1420                 1425             


Ile Ile  Asp Glu Pro Ile Arg  Pro Val Asn Ile Pro  Arg Lys Glu 
    1430                 1435                 1440             


Lys Asp  Phe Gln Gly Met Leu  Glu Tyr Lys Lys Glu  Asp Glu Gln 
    1445                 1450                 1455             


Lys Leu  Val Lys Asn Leu Ile  Leu Glu Leu Lys Pro  Arg Gly Val 
    1460                 1465                 1470             


Ala Val  Asn Leu Ile Pro Gly  Leu Pro Ala Tyr Ile  Leu Phe Met 
    1475                 1480                 1485             


Cys Val  Arg His Ala Asp Tyr  Leu Asn Asp Asp Gln  Lys Val Arg 
    1490                 1495                 1500             


Ser Leu  Leu Thr Ser Thr Ile  Asn Ser Ile Lys Lys  Val Leu Lys 
    1505                 1510                 1515             


Lys Arg  Gly Asp Asp Phe Glu  Thr Val Ser Phe Trp  Leu Ser Asn 
    1520                 1525                 1530             


Thr Cys  Arg Phe Leu His Cys  Leu Lys Gln Tyr Ser  Gly Glu Glu 
    1535                 1540                 1545             


Gly Phe  Met Lys His Asn Thr  Ser Arg Gln Asn Glu  His Cys Leu 
    1550                 1555                 1560             


Thr Asn  Phe Asp Leu Ala Glu  Tyr Arg Gln Val Leu  Ser Asp Leu 
    1565                 1570                 1575             


Ala Ile  Gln Ile Tyr Gln Gln  Leu Val Arg Val Leu  Glu Asn Ile 
    1580                 1585                 1590             


Leu Gln  Pro Met Ile Val Ser  Gly Met Leu Glu His  Glu Thr Ile 
    1595                 1600                 1605             


Gln Gly  Val Ser Gly Val Lys  Pro Thr Gly Leu Arg  Lys Arg Thr 
    1610                 1615                 1620             


Ser Ser  Ile Ala Asp Glu Gly  Thr Tyr Thr Leu Asp  Ser Ile Leu 
    1625                 1630                 1635             


Arg Gln  Leu Asn Ser Phe His  Ser Val Met Cys Gln  His Gly Met 
    1640                 1645                 1650             


Asp Pro  Glu Leu Ile Lys Gln  Val Val Lys Gln Met  Phe Tyr Ile 
    1655                 1660                 1665             


Ile Gly  Ala Ile Thr Leu Asn  Asn Leu Leu Leu Arg  Lys Asp Met 
    1670                 1675                 1680             


Cys Ser  Trp Ser Lys Gly Met  Gln Ile Arg Tyr Asn  Val Ser Gln 
    1685                 1690                 1695             


Leu Glu  Glu Trp Leu Arg Asp  Lys Asn Leu Met Asn  Ser Gly Ala 
    1700                 1705                 1710             


Lys Glu  Thr Leu Glu Pro Leu  Ile Gln Ala Ala Gln  Leu Leu Gln 
    1715                 1720                 1725             


Val Lys  Lys Lys Thr Asp Asp  Asp Ala Glu Ala Ile  Cys Ser Met 
    1730                 1735                 1740             


Cys Asn  Ala Leu Thr Thr Ala  Gln Ile Val Lys Val  Leu Asn Leu 
    1745                 1750                 1755             


Tyr Thr  Pro Val Asn Glu Phe  Glu Glu Arg Val Ser  Val Ser Phe 
    1760                 1765                 1770             


Ile Arg  Thr Ile Gln Met Arg  Leu Arg Asp Arg Lys  Asp Ser Pro 
    1775                 1780                 1785             


Gln Leu  Leu Met Asp Ala Lys  His Ile Phe Pro Val  Thr Phe Pro 
    1790                 1795                 1800             


Phe Asn  Pro Ser Ser Leu Ala  Leu Glu Thr Ile Gln  Ile Pro Ala 
    1805                 1810                 1815             


Ser Leu  Gly Leu Gly Phe Ile  Ser Arg Val 
    1820                 1825             


<210>  4005
<211>  666
<212>  PRT
<213>  homo sapiens

<400>  4005

Met Glu Gln Glu Pro Gln Asn Gly Glu Pro Ala Glu Ile Lys Ile Ile 
1               5                   10                  15      


Arg Glu Ala Tyr Lys Lys Ala Phe Leu Phe Val Asn Lys Gly Leu Asn 
            20                  25                  30          


Thr Asp Glu Leu Gly Gln Lys Glu Glu Ala Lys Asn Tyr Tyr Lys Gln 
        35                  40                  45              


Gly Ile Gly His Leu Leu Arg Gly Ile Ser Ile Ser Ser Lys Glu Ser 
    50                  55                  60                  


Glu His Thr Gly Pro Gly Trp Glu Ser Ala Arg Gln Met Gln Gln Lys 
65                  70                  75                  80  


Met Lys Glu Thr Leu Gln Asn Val Arg Thr Arg Leu Glu Ile Leu Glu 
                85                  90                  95      


Lys Gly Leu Ala Thr Ser Leu Gln Asn Asp Leu Gln Glu Val Pro Lys 
            100                 105                 110         


Leu Tyr Pro Glu Phe Pro Pro Lys Asp Met Cys Glu Lys Leu Pro Glu 
        115                 120                 125             


Pro Gln Ser Phe Ser Ser Ala Pro Gln His Ala Glu Val Asn Gly Asn 
    130                 135                 140                 


Thr Ser Thr Pro Ser Ala Gly Ala Val Ala Ala Pro Ala Ser Leu Ser 
145                 150                 155                 160 


Leu Pro Ser Gln Ser Cys Pro Ala Glu Ala Pro Pro Ala Tyr Thr Pro 
                165                 170                 175     


Gln Ala Ala Glu Gly His Tyr Thr Val Ser Tyr Gly Thr Asp Ser Gly 
            180                 185                 190         


Glu Phe Ser Ser Val Gly Glu Glu Phe Tyr Arg Asn His Ser Gln Pro 
        195                 200                 205             


Pro Pro Leu Glu Thr Leu Gly Leu Asp Ala Asp Glu Leu Ile Leu Ile 
    210                 215                 220                 


Pro Asn Gly Val Gln Ile Phe Phe Val Asn Pro Ala Gly Glu Val Ser 
225                 230                 235                 240 


Ala Pro Ser Tyr Pro Gly Tyr Leu Arg Ile Val Arg Phe Leu Asp Asn 
                245                 250                 255     


Ser Leu Asp Thr Val Leu Asn Arg Pro Pro Gly Phe Leu Gln Val Cys 
            260                 265                 270         


Asp Trp Leu Tyr Pro Leu Val Pro Asp Arg Ser Pro Val Leu Lys Cys 
        275                 280                 285             


Thr Ala Gly Ala Tyr Met Phe Pro Asp Thr Met Leu Gln Ala Ala Gly 
    290                 295                 300                 


Cys Phe Val Gly Val Val Leu Ser Ser Glu Leu Pro Glu Asp Asp Arg 
305                 310                 315                 320 


Glu Leu Phe Glu Asp Leu Leu Arg Gln Met Ser Asp Leu Arg Leu Gln 
                325                 330                 335     


Ala Asn Trp Asn Arg Ala Glu Glu Glu Asn Glu Phe Gln Ile Pro Gly 
            340                 345                 350         


Arg Thr Arg Pro Ser Ser Asp Gln Leu Lys Glu Ala Ser Gly Thr Asp 
        355                 360                 365             


Val Lys Gln Leu Asp Gln Gly Asn Lys Asp Val Arg His Lys Gly Lys 
    370                 375                 380                 


Arg Gly Lys Arg Ala Lys Asp Thr Ser Ser Glu Glu Val Asn Leu Ser 
385                 390                 395                 400 


His Ile Val Pro Cys Glu Pro Val Pro Glu Glu Lys Pro Lys Glu Leu 
                405                 410                 415     


Pro Glu Trp Ser Glu Lys Val Ala His Asn Ile Leu Ser Gly Ala Ser 
            420                 425                 430         


Trp Val Ser Trp Gly Leu Val Lys Gly Ala Glu Ile Thr Gly Lys Ala 
        435                 440                 445             


Ile Gln Lys Gly Ala Ser Lys Leu Arg Glu Arg Ile Gln Pro Glu Glu 
    450                 455                 460                 


Lys Pro Val Glu Val Ser Pro Ala Val Thr Lys Gly Leu Tyr Ile Ala 
465                 470                 475                 480 


Lys Gln Ala Thr Gly Gly Ala Ala Lys Val Ser Gln Phe Leu Val Asp 
                485                 490                 495     


Gly Val Cys Thr Val Ala Asn Cys Val Gly Lys Glu Leu Ala Pro His 
            500                 505                 510         


Val Lys Lys His Gly Ser Lys Leu Val Pro Glu Ser Leu Lys Lys Asp 
        515                 520                 525             


Lys Asp Gly Lys Ser Pro Leu Asp Gly Ala Met Val Val Ala Ala Ser 
    530                 535                 540                 


Ser Val Gln Gly Phe Ser Thr Val Trp Gln Gly Leu Glu Cys Ala Ala 
545                 550                 555                 560 


Lys Cys Ile Val Asn Asn Val Ser Ala Glu Thr Val Gln Thr Val Arg 
                565                 570                 575     


Tyr Lys Tyr Gly Tyr Asn Ala Gly Glu Ala Thr His His Ala Val Asp 
            580                 585                 590         


Ser Ala Val Asn Val Gly Val Thr Ala Tyr Asn Ile Asn Asn Ile Gly 
        595                 600                 605             


Ile Lys Ala Met Val Lys Lys Thr Ala Thr Gln Thr Gly His Thr Leu 
    610                 615                 620                 


Leu Glu Asp Tyr Gln Ile Val Asp Asn Ser Gln Arg Glu Asn Gln Glu 
625                 630                 635                 640 


Gly Ala Ala Asn Val Asn Val Arg Gly Glu Lys Asp Glu Gln Thr Lys 
                645                 650                 655     


Glu Val Lys Glu Ala Lys Lys Lys Asp Lys 
            660                 665     


<210>  4006
<211>  296
<212>  PRT
<213>  homo sapiens

<400>  4006

Met Tyr Phe Ser Gln Glu Glu Trp Glu Leu Leu Asp Pro Thr Gln Lys 
1               5                   10                  15      


Ala Leu Tyr Asn Asp Val Met Gln Glu Asn Tyr Glu Thr Val Ile Ser 
            20                  25                  30          


Leu Ala Leu Phe Val Leu Pro Lys Pro Lys Val Ile Ser Cys Leu Glu 
        35                  40                  45              


Gln Gly Glu Glu Pro Trp Val Gln Val Ser Pro Glu Phe Lys Asp Ser 
    50                  55                  60                  


Ala Gly Lys Ser Pro Thr Gly Leu Lys Leu Lys Asn Asp Thr Glu Asn 
65                  70                  75                  80  


His Gln Pro Val Ser Leu Ser Asp Leu Glu Ile Gln Ala Ser Ala Gly 
                85                  90                  95      


Val Ile Ser Lys Lys Ala Lys Val Lys Val Pro Gln Lys Thr Ala Gly 
            100                 105                 110         


Lys Glu Asn His Phe Asp Met His Arg Val Gly Lys Trp His Gln Asp 
        115                 120                 125             


Phe Pro Val Lys Lys Arg Lys Lys Leu Ser Thr Trp Lys Gln Glu Leu 
    130                 135                 140                 


Leu Lys Leu Met Asp Arg His Lys Lys Asp Cys Ala Arg Glu Lys Pro 
145                 150                 155                 160 


Phe Lys Cys Gln Glu Cys Gly Lys Thr Phe Arg Val Ser Ser Asp Leu 
                165                 170                 175     


Ile Lys His Gln Arg Ile His Thr Glu Glu Lys Pro Tyr Lys Cys Gln 
            180                 185                 190         


Gln Cys Asp Lys Arg Phe Arg Trp Ser Ser Asp Leu Asn Lys His Leu 
        195                 200                 205             


Thr Thr His Gln Gly Ile Lys Pro Tyr Lys Cys Ser Trp Cys Gly Lys 
    210                 215                 220                 


Ser Phe Ser Gln Asn Thr Asn Leu His Thr His Gln Arg Thr His Thr 
225                 230                 235                 240 


Gly Glu Lys Pro Phe Thr Cys His Glu Cys Gly Lys Lys Phe Ser Gln 
                245                 250                 255     


Asn Ser His Leu Ile Lys His Arg Arg Thr His Thr Gly Glu Gln Pro 
            260                 265                 270         


Tyr Thr Cys Ser Ile Cys Arg Arg Asn Phe Ser Arg Arg Ser Ser Leu 
        275                 280                 285             


Leu Arg His Gln Lys Leu His Leu 
    290                 295     


<210>  4007
<211>  342
<212>  PRT
<213>  homo sapiens

<400>  4007

Met Ala Ala Glu Glu Glu Asp Glu Val Glu Trp Val Val Glu Ser Ile 
1               5                   10                  15      


Ala Gly Phe Leu Arg Gly Pro Asp Trp Ser Ile Pro Ile Leu Asp Phe 
            20                  25                  30          


Val Glu Gln Lys Cys Glu Val Phe Asp Asp Glu Glu Glu Ser Lys Leu 
        35                  40                  45              


Thr Tyr Thr Glu Ile His Gln Glu Tyr Lys Glu Leu Val Glu Lys Leu 
    50                  55                  60                  


Leu Glu Gly Tyr Leu Lys Glu Ile Gly Ile Asn Glu Asp Gln Phe Gln 
65                  70                  75                  80  


Glu Ala Cys Thr Ser Pro Leu Ala Lys Thr His Thr Ser Gln Ala Ile 
                85                  90                  95      


Leu Gln Pro Val Leu Ala Ala Glu Asp Phe Thr Ile Phe Lys Ala Met 
            100                 105                 110         


Met Val Gln Lys Asn Ile Glu Met Gln Leu Gln Ala Ile Arg Ile Ile 
        115                 120                 125             


Gln Glu Arg Asn Gly Val Leu Pro Asp Cys Leu Thr Asp Gly Ser Asp 
    130                 135                 140                 


Val Val Ser Asp Leu Glu His Glu Glu Met Lys Ile Leu Arg Glu Val 
145                 150                 155                 160 


Leu Arg Lys Ser Lys Glu Glu Tyr Asp Gln Glu Glu Glu Arg Lys Arg 
                165                 170                 175     


Lys Lys Gln Leu Ser Glu Ala Lys Thr Glu Glu Pro Thr Val His Ser 
            180                 185                 190         


Ser Glu Ala Ala Ile Met Asn Asn Ser Gln Gly Asp Gly Glu His Phe 
        195                 200                 205             


Ala His Pro Pro Ser Glu Val Lys Met His Phe Ala Asn Gln Ser Ile 
    210                 215                 220                 


Glu Pro Leu Gly Arg Lys Val Glu Arg Ser Glu Thr Ser Ser Leu Pro 
225                 230                 235                 240 


Gln Lys Asp Leu Lys Ile Pro Gly Leu Glu His Ala Ser Ile Glu Gly 
                245                 250                 255     


Pro Ile Ala Asn Leu Ser Val Leu Gly Thr Glu Glu Leu Arg Gln Arg 
            260                 265                 270         


Glu His Tyr Leu Lys Gln Lys Arg Asp Lys Leu Met Ser Met Arg Lys 
        275                 280                 285             


Asp Met Arg Thr Lys Gln Ile Gln Asn Met Glu Gln Lys Gly Lys Pro 
    290                 295                 300                 


Thr Gly Glu Val Glu Glu Met Thr Glu Lys Pro Glu Met Thr Ala Glu 
305                 310                 315                 320 


Glu Lys Gln Thr Leu Leu Lys Arg Arg Leu Leu Ala Glu Lys Leu Lys 
                325                 330                 335     


Glu Glu Val Ile Asn Lys 
            340         


<210>  4008
<211>  682
<212>  PRT
<213>  homo sapiens

<400>  4008

Met Gln Leu Glu His Cys Leu Ser Pro Ser Ile Met Leu Ser Lys Lys 
1               5                   10                  15      


Phe Leu Asn Val Ser Ser Ser Tyr Pro His Ser Gly Gly Ser Glu Leu 
            20                  25                  30          


Val Leu His Asp His Pro Ile Ile Ser Thr Thr Asp Asn Leu Glu Arg 
        35                  40                  45              


Ser Ser Pro Leu Lys Lys Ile Thr Arg Gly Met Thr Asn Gln Ser Asp 
    50                  55                  60                  


Thr Asp Asn Phe Pro Asp Ser Lys Asp Ser Pro Gly Asp Val Gln Arg 
65                  70                  75                  80  


Ser Lys Leu Ser Pro Val Leu Asp Gly Val Ser Glu Leu Arg His Ser 
                85                  90                  95      


Phe Asp Gly Ser Ala Ala Asp Arg Tyr Leu Leu Ser Gln Ser Ser Gln 
            100                 105                 110         


Pro Gln Ser Ala Ala Thr Ala Pro Ser Ala Met Phe Pro Tyr Pro Gly 
        115                 120                 125             


Gln His Gly Pro Ala His Pro Ala Phe Ser Ile Gly Ser Pro Ser Arg 
    130                 135                 140                 


Tyr Met Ala His His Pro Val Ile Thr Asn Gly Ala Tyr Asn Ser Leu 
145                 150                 155                 160 


Leu Ser Asn Ser Ser Pro Gln Gly Tyr Pro Thr Ala Gly Tyr Pro Tyr 
                165                 170                 175     


Pro Gln Gln Tyr Gly His Ser Tyr Gln Gly Ala Pro Phe Tyr Gln Phe 
            180                 185                 190         


Ser Ser Thr Gln Pro Gly Leu Val Pro Gly Lys Ala Gln Val Tyr Leu 
        195                 200                 205             


Cys Asn Arg Pro Leu Trp Leu Lys Phe His Arg His Gln Thr Glu Met 
    210                 215                 220                 


Ile Ile Thr Lys Gln Gly Arg Arg Met Phe Pro Phe Leu Ser Phe Asn 
225                 230                 235                 240 


Ile Ser Gly Leu Asp Pro Thr Ala His Tyr Asn Ile Phe Val Asp Val 
                245                 250                 255     


Ile Leu Ala Asp Pro Asn His Trp Arg Phe Gln Gly Gly Lys Trp Val 
            260                 265                 270         


Pro Cys Gly Lys Ala Asp Thr Asn Val Gln Gly Asn Arg Val Tyr Met 
        275                 280                 285             


His Pro Asp Ser Pro Asn Thr Gly Ala His Trp Met Arg Gln Glu Ile 
    290                 295                 300                 


Ser Phe Gly Lys Leu Lys Leu Thr Asn Asn Lys Gly Ala Ser Asn Asn 
305                 310                 315                 320 


Asn Gly Gln Met Val Val Leu Gln Ser Leu His Lys Tyr Gln Pro Arg 
                325                 330                 335     


Leu His Val Val Glu Val Asn Glu Asp Gly Thr Glu Asp Thr Ser Gln 
            340                 345                 350         


Pro Gly Arg Val Gln Thr Phe Thr Phe Pro Glu Thr Gln Phe Ile Ala 
        355                 360                 365             


Val Thr Ala Tyr Gln Asn Thr Asp Ile Thr Gln Leu Lys Ile Asp His 
    370                 375                 380                 


Asn Pro Phe Ala Lys Gly Phe Arg Asp Asn Tyr Asp Thr Ile Tyr Thr 
385                 390                 395                 400 


Gly Cys Asp Met Asp Arg Leu Thr Pro Ser Pro Asn Asp Ser Pro Arg 
                405                 410                 415     


Ser Gln Ile Val Pro Gly Ala Arg Tyr Ala Met Ala Gly Ser Phe Leu 
            420                 425                 430         


Gln Asp Gln Phe Val Ser Asn Tyr Ala Lys Ala Arg Phe His Pro Gly 
        435                 440                 445             


Ala Gly Ala Gly Pro Gly Pro Gly Thr Asp Arg Ser Val Pro His Thr 
    450                 455                 460                 


Asn Gly Leu Leu Ser Pro Gln Gln Ala Glu Asp Pro Gly Ala Pro Ser 
465                 470                 475                 480 


Pro Gln Arg Trp Phe Val Thr Pro Ala Asn Asn Arg Leu Asp Phe Ala 
                485                 490                 495     


Ala Ser Ala Tyr Asp Thr Ala Thr Asp Phe Ala Gly Asn Ala Ala Thr 
            500                 505                 510         


Leu Leu Ser Tyr Ala Ala Ala Gly Val Lys Ala Leu Pro Leu Gln Ala 
        515                 520                 525             


Ala Gly Cys Thr Gly Arg Pro Leu Gly Tyr Tyr Ala Asp Pro Ser Gly 
    530                 535                 540                 


Trp Gly Ala Arg Ser Pro Pro Gln Tyr Cys Gly Thr Lys Ser Gly Ser 
545                 550                 555                 560 


Val Leu Pro Cys Trp Pro Asn Ser Ala Ala Ala Ala Ala Arg Met Ala 
                565                 570                 575     


Gly Ala Asn Pro Tyr Leu Gly Glu Glu Ala Glu Gly Leu Ala Ala Glu 
            580                 585                 590         


Arg Ser Pro Leu Pro Pro Gly Ala Ala Glu Asp Ala Lys Pro Lys Asp 
        595                 600                 605             


Leu Ser Asp Ser Ser Trp Ile Glu Thr Pro Ser Ser Ile Lys Ser Ile 
    610                 615                 620                 


Asp Ser Ser Asp Ser Gly Ile Tyr Glu Gln Ala Lys Arg Arg Arg Ile 
625                 630                 635                 640 


Ser Pro Ala Asp Thr Pro Val Ser Glu Ser Ser Ser Pro Leu Lys Ser 
                645                 650                 655     


Glu Val Leu Ala Gln Arg Asp Cys Glu Lys Asn Cys Ala Lys Asp Ile 
            660                 665                 670         


Ser Gly Tyr Tyr Gly Phe Tyr Ser His Ser 
        675                 680         


<210>  4009
<211>  100
<212>  PRT
<213>  homo sapiens

<400>  4009

Met Gln Lys Pro Cys Lys Glu Asn Glu Gly Lys Pro Lys Cys Ser Val 
1               5                   10                  15      


Pro Lys Arg Glu Glu Lys Arg Pro Tyr Gly Glu Phe Glu Arg Gln Gln 
            20                  25                  30          


Thr Glu Gly Asn Phe Arg Gln Arg Leu Leu Gln Ser Leu Glu Glu Phe 
        35                  40                  45              


Lys Glu Asp Ile Asp Tyr Arg His Phe Lys Asp Glu Glu Met Thr Arg 
    50                  55                  60                  


Glu Gly Asp Glu Met Glu Arg Cys Leu Glu Glu Ile Arg Gly Leu Arg 
65                  70                  75                  80  


Lys Lys Phe Arg Ala Leu His Ser Asn His Arg His Ser Arg Asp Arg 
                85                  90                  95      


Pro Tyr Pro Ile 
            100 


<210>  4010
<211>  471
<212>  PRT
<213>  homo sapiens

<400>  4010

Met Ser Tyr Pro Gln Gly Tyr Leu Tyr Gln Ala Pro Gly Ser Leu Ala 
1               5                   10                  15      


Leu Tyr Ser Cys Pro Ala Tyr Gly Ala Ser Ala Leu Ala Ala Pro Arg 
            20                  25                  30          


Ser Glu Glu Leu Ala Arg Ser Ala Ser Gly Ser Ala Phe Ser Pro Tyr 
        35                  40                  45              


Pro Gly Ser Ala Ala Phe Thr Ala Gln Ala Ala Thr Gly Phe Gly Ser 
    50                  55                  60                  


Pro Leu Gln Tyr Ser Ala Asp Ala Ala Ala Ala Ala Ala Gly Phe Pro 
65                  70                  75                  80  


Ser Tyr Met Gly Ala Pro Tyr Asp Ala His Thr Thr Gly Met Thr Gly 
                85                  90                  95      


Ala Ile Ser Tyr His Pro Tyr Gly Ser Ala Ala Tyr Pro Tyr Gln Leu 
            100                 105                 110         


Asn Asp Pro Ala Tyr Arg Lys Asn Ala Thr Arg Asp Ala Thr Ala Thr 
        115                 120                 125             


Leu Lys Ala Trp Leu Asn Glu His Arg Lys Asn Pro Tyr Pro Thr Lys 
    130                 135                 140                 


Gly Glu Lys Ile Met Leu Ala Ile Ile Thr Lys Met Thr Leu Thr Gln 
145                 150                 155                 160 


Val Ser Thr Trp Phe Ala Asn Ala Arg Arg Arg Leu Lys Lys Glu Asn 
                165                 170                 175     


Lys Met Thr Trp Ala Pro Arg Asn Lys Ser Glu Asp Glu Asp Glu Asp 
            180                 185                 190         


Glu Gly Asp Ala Thr Arg Ser Lys Asp Glu Ser Pro Asp Lys Ala Gln 
        195                 200                 205             


Glu Gly Thr Glu Thr Ser Ala Glu Asp Glu Gly Ile Ser Leu His Val 
    210                 215                 220                 


Asp Ser Leu Thr Asp His Ser Cys Ser Ala Glu Ser Asp Gly Glu Lys 
225                 230                 235                 240 


Leu Pro Cys Arg Ala Gly Asp Pro Leu Cys Glu Ser Gly Ser Glu Cys 
                245                 250                 255     


Lys Asp Lys Tyr Asp Asp Leu Glu Asp Asp Glu Asp Asp Asp Glu Glu 
            260                 265                 270         


Gly Glu Arg Gly Leu Ala Pro Pro Lys Pro Val Thr Ser Ser Pro Leu 
        275                 280                 285             


Thr Gly Leu Glu Ala Pro Leu Leu Ser Pro Pro Pro Glu Ala Ala Pro 
    290                 295                 300                 


Arg Gly Gly Arg Lys Thr Pro Gln Gly Ser Arg Thr Ser Pro Gly Ala 
305                 310                 315                 320 


Pro Pro Pro Ala Ser Lys Pro Lys Leu Trp Ser Leu Ala Glu Ile Ala 
                325                 330                 335     


Thr Ser Asp Leu Lys Gln Pro Ser Leu Gly Pro Gly Cys Gly Pro Pro 
            340                 345                 350         


Gly Leu Pro Ala Ala Ala Ala Pro Ala Ser Thr Gly Ala Pro Pro Gly 
        355                 360                 365             


Gly Ser Pro Tyr Pro Ala Ser Pro Leu Leu Gly Arg Pro Leu Tyr Tyr 
    370                 375                 380                 


Thr Ser Pro Phe Tyr Gly Asn Tyr Thr Asn Tyr Gly Asn Leu Asn Ala 
385                 390                 395                 400 


Ala Leu Gln Gly Gln Gly Leu Leu Arg Tyr Asn Ser Ala Ala Ala Ala 
                405                 410                 415     


Pro Gly Glu Ala Leu His Thr Ala Pro Lys Ala Ala Ser Asp Ala Gly 
            420                 425                 430         


Lys Ala Gly Ala His Pro Leu Glu Ser His Tyr Arg Ser Pro Gly Gly 
        435                 440                 445             


Gly Tyr Glu Pro Lys Lys Asp Ala Ser Glu Gly Cys Thr Val Val Gly 
    450                 455                 460                 


Gly Gly Val Gln Pro Tyr Leu 
465                 470     


<210>  4011
<211>  471
<212>  PRT
<213>  homo sapiens

<400>  4011

Met Ser Tyr Pro Gln Gly Tyr Leu Tyr Gln Ala Pro Gly Ser Leu Ala 
1               5                   10                  15      


Leu Tyr Ser Cys Pro Ala Tyr Gly Ala Ser Ala Leu Ala Ala Pro Arg 
            20                  25                  30          


Ser Glu Glu Leu Ala Arg Ser Ala Ser Gly Ser Ala Phe Ser Pro Tyr 
        35                  40                  45              


Pro Gly Ser Ala Ala Phe Thr Ala Gln Ala Ala Thr Gly Phe Gly Ser 
    50                  55                  60                  


Pro Leu Gln Tyr Ser Ala Asp Ala Ala Ala Ala Ala Ala Gly Phe Pro 
65                  70                  75                  80  


Ser Tyr Met Gly Ala Pro Tyr Asp Ala His Thr Thr Gly Met Thr Gly 
                85                  90                  95      


Ala Ile Ser Tyr His Pro Tyr Gly Ser Ala Ala Tyr Pro Tyr Gln Leu 
            100                 105                 110         


Asn Asp Pro Ala Tyr Arg Lys Asn Ala Thr Arg Asp Ala Thr Ala Thr 
        115                 120                 125             


Leu Lys Ala Trp Leu Asn Glu His Arg Lys Asn Pro Tyr Pro Thr Lys 
    130                 135                 140                 


Gly Glu Lys Ile Met Leu Ala Ile Ile Thr Lys Met Thr Leu Thr Gln 
145                 150                 155                 160 


Val Ser Thr Trp Phe Ala Asn Ala Arg Arg Arg Leu Lys Lys Glu Asn 
                165                 170                 175     


Lys Met Thr Trp Ala Pro Arg Asn Lys Ser Glu Asp Glu Asp Glu Asp 
            180                 185                 190         


Glu Gly Asp Ala Thr Arg Ser Lys Asp Glu Ser Pro Asp Lys Ala Gln 
        195                 200                 205             


Glu Gly Thr Glu Thr Ser Ala Glu Asp Glu Gly Ile Ser Leu His Val 
    210                 215                 220                 


Asp Ser Leu Thr Asp His Ser Cys Ser Ala Glu Ser Asp Gly Glu Lys 
225                 230                 235                 240 


Leu Pro Cys Arg Ala Gly Asp Pro Leu Cys Glu Ser Gly Ser Glu Cys 
                245                 250                 255     


Lys Asp Lys Tyr Asp Asp Leu Glu Asp Asp Glu Asp Asp Asp Glu Glu 
            260                 265                 270         


Gly Glu Arg Gly Leu Ala Pro Pro Lys Pro Val Thr Ser Ser Pro Leu 
        275                 280                 285             


Thr Gly Leu Glu Ala Pro Leu Leu Ser Pro Pro Pro Glu Ala Ala Pro 
    290                 295                 300                 


Arg Gly Gly Arg Lys Thr Pro Gln Gly Ser Arg Thr Ser Pro Gly Ala 
305                 310                 315                 320 


Pro Pro Pro Ala Ser Lys Pro Lys Leu Trp Ser Leu Ala Glu Ile Ala 
                325                 330                 335     


Thr Ser Asp Leu Lys Gln Pro Ser Leu Gly Pro Gly Cys Gly Pro Pro 
            340                 345                 350         


Gly Leu Pro Ala Ala Ala Ala Pro Ala Ser Thr Gly Ala Pro Pro Gly 
        355                 360                 365             


Gly Ser Pro Tyr Pro Ala Ser Pro Leu Leu Gly Arg Pro Leu Tyr Tyr 
    370                 375                 380                 


Thr Ser Pro Phe Tyr Gly Asn Tyr Thr Asn Tyr Gly Asn Leu Asn Ala 
385                 390                 395                 400 


Ala Leu Gln Gly Gln Gly Leu Leu Arg Tyr Asn Ser Ala Ala Ala Ala 
                405                 410                 415     


Pro Gly Glu Ala Leu His Thr Ala Pro Lys Ala Ala Ser Asp Ala Gly 
            420                 425                 430         


Lys Ala Gly Ala His Pro Leu Glu Ser His Tyr Arg Ser Pro Gly Gly 
        435                 440                 445             


Gly Tyr Glu Pro Lys Lys Asp Ala Ser Glu Gly Cys Thr Val Val Gly 
    450                 455                 460                 


Gly Gly Val Gln Pro Tyr Leu 
465                 470     


<210>  4012
<211>  1534
<212>  PRT
<213>  homo sapiens

<400>  4012

Met Ala Leu Thr Pro Gly Trp Gly Ser Ser Ala Gly Pro Val Arg Pro 
1               5                   10                  15      


Glu Leu Trp Leu Leu Leu Trp Ala Ala Ala Trp Arg Leu Gly Ala Ser 
            20                  25                  30          


Ala Cys Pro Ala Leu Cys Thr Cys Thr Gly Thr Thr Val Asp Cys His 
        35                  40                  45              


Gly Thr Gly Leu Gln Ala Ile Pro Lys Asn Ile Pro Arg Asn Thr Glu 
    50                  55                  60                  


Arg Leu Glu Leu Asn Gly Asn Asn Ile Thr Arg Ile His Lys Asn Asp 
65                  70                  75                  80  


Phe Ala Gly Leu Lys Gln Leu Arg Val Leu Gln Leu Met Glu Asn Gln 
                85                  90                  95      


Ile Gly Ala Val Glu Arg Gly Ala Phe Asp Asp Met Lys Glu Leu Glu 
            100                 105                 110         


Arg Leu Arg Leu Asn Arg Asn Gln Leu His Met Leu Pro Glu Leu Leu 
        115                 120                 125             


Phe Gln Asn Asn Gln Ala Leu Ser Arg Leu Asp Leu Ser Glu Asn Ala 
    130                 135                 140                 


Ile Gln Ala Ile Pro Arg Lys Ala Phe Arg Gly Ala Thr Asp Leu Lys 
145                 150                 155                 160 


Asn Leu Gln Leu Asp Lys Asn Gln Ile Ser Cys Ile Glu Glu Gly Ala 
                165                 170                 175     


Phe Arg Ala Leu Arg Gly Leu Glu Val Leu Thr Leu Asn Asn Asn Asn 
            180                 185                 190         


Ile Thr Thr Ile Pro Val Ser Ser Phe Asn His Met Pro Lys Leu Arg 
        195                 200                 205             


Thr Phe Arg Leu His Ser Asn His Leu Phe Cys Asp Cys His Leu Ala 
    210                 215                 220                 


Trp Leu Ser Gln Trp Leu Arg Gln Arg Pro Thr Ile Gly Leu Phe Thr 
225                 230                 235                 240 


Gln Cys Ser Gly Pro Ala Ser Leu Arg Gly Leu Asn Val Ala Glu Val 
                245                 250                 255     


Gln Lys Ser Glu Phe Ser Cys Ser Gly Gln Gly Glu Ala Gly Arg Val 
            260                 265                 270         


Pro Thr Cys Thr Leu Ser Ser Gly Ser Cys Pro Ala Met Cys Thr Cys 
        275                 280                 285             


Ser Asn Gly Ile Val Asp Cys Arg Gly Lys Gly Leu Thr Ala Ile Pro 
    290                 295                 300                 


Ala Asn Leu Pro Glu Thr Met Thr Glu Ile Arg Leu Glu Leu Asn Gly 
305                 310                 315                 320 


Ile Lys Ser Ile Pro Pro Gly Ala Phe Ser Pro Tyr Arg Lys Leu Arg 
                325                 330                 335     


Arg Ile Asp Leu Ser Asn Asn Gln Ile Ala Glu Ile Ala Pro Asp Ala 
            340                 345                 350         


Phe Gln Gly Leu Arg Ser Leu Asn Ser Leu Val Leu Tyr Gly Asn Lys 
        355                 360                 365             


Ile Thr Asp Leu Pro Arg Gly Val Phe Gly Gly Leu Tyr Thr Leu Gln 
    370                 375                 380                 


Leu Leu Leu Leu Asn Ala Asn Lys Ile Asn Cys Ile Arg Pro Asp Ala 
385                 390                 395                 400 


Phe Gln Asp Leu Gln Asn Leu Ser Leu Leu Ser Leu Tyr Asp Asn Lys 
                405                 410                 415     


Ile Gln Ser Leu Ala Lys Gly Thr Phe Thr Ser Leu Arg Ala Ile Gln 
            420                 425                 430         


Thr Leu His Leu Ala Gln Asn Pro Phe Ile Cys Asp Cys Asn Leu Lys 
        435                 440                 445             


Trp Leu Ala Asp Phe Leu Arg Thr Asn Pro Ile Glu Thr Ser Gly Ala 
    450                 455                 460                 


Arg Cys Ala Ser Pro Arg Arg Leu Ala Asn Lys Arg Ile Gly Gln Ile 
465                 470                 475                 480 


Lys Ser Lys Lys Phe Arg Cys Ser Ala Lys Glu Gln Tyr Phe Ile Pro 
                485                 490                 495     


Gly Thr Glu Asp Tyr Gln Leu Asn Ser Glu Cys Asn Ser Asp Val Val 
            500                 505                 510         


Cys Pro His Lys Cys Arg Cys Glu Ala Asn Val Val Glu Cys Ser Ser 
        515                 520                 525             


Leu Lys Leu Thr Lys Ile Pro Glu Arg Ile Pro Gln Ser Thr Ala Glu 
    530                 535                 540                 


Leu Arg Leu Asn Asn Asn Glu Ile Ser Ile Leu Glu Ala Thr Gly Met 
545                 550                 555                 560 


Phe Lys Lys Leu Thr His Leu Lys Lys Ile Asn Leu Ser Asn Asn Lys 
                565                 570                 575     


Val Ser Glu Ile Glu Asp Gly Ala Phe Glu Gly Ala Ala Ser Val Ser 
            580                 585                 590         


Glu Leu His Leu Thr Ala Asn Gln Leu Glu Ser Ile Arg Ser Gly Met 
        595                 600                 605             


Phe Arg Gly Leu Asp Gly Leu Arg Thr Leu Met Leu Arg Asn Asn Arg 
    610                 615                 620                 


Ile Ser Cys Ile His Asn Asp Ser Phe Thr Gly Leu Arg Asn Val Arg 
625                 630                 635                 640 


Leu Leu Ser Leu Tyr Asp Asn Gln Ile Thr Thr Val Ser Pro Gly Ala 
                645                 650                 655     


Phe Asp Thr Leu Gln Ser Leu Ser Thr Leu Asn Leu Leu Ala Asn Pro 
            660                 665                 670         


Phe Asn Cys Asn Cys Gln Leu Ala Trp Leu Gly Gly Trp Leu Arg Lys 
        675                 680                 685             


Arg Lys Ile Val Thr Gly Asn Pro Arg Cys Gln Asn Pro Asp Phe Leu 
    690                 695                 700                 


Arg Gln Ile Pro Leu Gln Asp Val Ala Phe Pro Asp Phe Arg Cys Glu 
705                 710                 715                 720 


Glu Gly Gln Glu Glu Gly Gly Cys Leu Pro Arg Pro Gln Cys Pro Gln 
                725                 730                 735     


Glu Cys Ala Cys Leu Asp Thr Val Val Arg Cys Ser Asn Lys His Leu 
            740                 745                 750         


Arg Ala Leu Pro Lys Gly Ile Pro Lys Asn Val Thr Glu Leu Tyr Leu 
        755                 760                 765             


Asp Gly Asn Gln Phe Thr Leu Val Pro Gly Gln Leu Ser Thr Phe Lys 
    770                 775                 780                 


Tyr Leu Gln Leu Val Asp Leu Ser Asn Asn Lys Ile Ser Ser Leu Ser 
785                 790                 795                 800 


Asn Ser Ser Phe Thr Asn Met Ser Gln Leu Thr Thr Leu Ile Leu Ser 
                805                 810                 815     


Tyr Asn Ala Leu Gln Cys Ile Pro Pro Leu Ala Phe Gln Gly Leu Arg 
            820                 825                 830         


Ser Leu Arg Leu Leu Ser Leu His Gly Asn Asp Ile Ser Thr Leu Gln 
        835                 840                 845             


Glu Gly Ile Phe Ala Asp Val Thr Ser Leu Ser His Leu Ala Ile Gly 
    850                 855                 860                 


Ala Asn Pro Leu Tyr Cys Asp Cys His Leu Arg Trp Leu Ser Ser Trp 
865                 870                 875                 880 


Val Lys Thr Gly Tyr Lys Glu Pro Gly Ile Ala Arg Cys Ala Gly Pro 
                885                 890                 895     


Gln Asp Met Glu Gly Lys Leu Leu Leu Thr Thr Pro Ala Lys Lys Phe 
            900                 905                 910         


Glu Cys Gln Gly Pro Pro Thr Leu Ala Val Gln Ala Lys Cys Asp Leu 
        915                 920                 925             


Cys Leu Ser Ser Pro Cys Gln Asn Gln Gly Thr Cys His Asn Asp Pro 
    930                 935                 940                 


Leu Glu Val Tyr Arg Cys Ala Cys Pro Ser Gly Tyr Lys Gly Arg Asp 
945                 950                 955                 960 


Cys Glu Val Ser Leu Asp Ser Cys Ser Ser Gly Pro Cys Glu Asn Gly 
                965                 970                 975     


Gly Thr Cys His Ala Gln Glu Gly Glu Asp Ala Pro Phe Thr Cys Ser 
            980                 985                 990         


Cys Pro Thr Gly Phe Glu Gly Pro  Thr Cys Gly Val Asn  Thr Asp Asp 
        995                 1000                 1005             


Cys Val  Asp His Ala Cys Ala  Asn Gly Gly Val Cys  Val Asp Gly 
    1010                 1015                 1020             


Val Gly  Asn Tyr Thr Cys Gln  Cys Pro Leu Gln Tyr  Glu Gly Lys 
    1025                 1030                 1035             


Ala Cys  Glu Gln Leu Val Asp  Leu Cys Ser Pro Asp  Leu Asn Pro 
    1040                 1045                 1050             


Cys Gln  His Glu Ala Gln Cys  Val Gly Thr Pro Asp  Gly Pro Arg 
    1055                 1060                 1065             


Cys Glu  Cys Met Pro Gly Tyr  Ala Gly Asp Asn Cys  Ser Glu Asn 
    1070                 1075                 1080             


Gln Asp  Asp Cys Arg Asp His  Arg Cys Gln Asn Gly  Ala Gln Cys 
    1085                 1090                 1095             


Met Asp  Glu Val Asn Ser Tyr  Ser Cys Leu Cys Ala  Glu Gly Tyr 
    1100                 1105                 1110             


Ser Gly  Gln Leu Cys Glu Ile  Pro Pro His Leu Pro  Ala Pro Lys 
    1115                 1120                 1125             


Ser Pro  Cys Glu Gly Thr Glu  Cys Gln Asn Gly Ala  Asn Cys Val 
    1130                 1135                 1140             


Asp Gln  Gly Asn Arg Pro Val  Cys Gln Cys Leu Pro  Gly Phe Gly 
    1145                 1150                 1155             


Gly Pro  Glu Cys Glu Lys Leu  Leu Ser Val Asn Phe  Val Asp Arg 
    1160                 1165                 1170             


Asp Thr  Tyr Leu Gln Phe Thr  Asp Leu Gln Asn Trp  Pro Arg Ala 
    1175                 1180                 1185             


Asn Ile  Thr Leu Gln Val Ser  Thr Ala Glu Asp Asn  Gly Ile Leu 
    1190                 1195                 1200             


Leu Tyr  Asn Gly Asp Asn Asp  His Ile Ala Val Glu  Leu Tyr Gln 
    1205                 1210                 1215             


Gly His  Val Arg Val Ser Tyr  Asp Pro Gly Ser Tyr  Pro Ser Ser 
    1220                 1225                 1230             


Ala Ile  Tyr Ser Ala Glu Thr  Ile Asn Asp Gly Gln  Phe His Thr 
    1235                 1240                 1245             


Val Glu  Leu Val Ala Phe Asp  Gln Met Val Asn Leu  Ser Ile Asp 
    1250                 1255                 1260             


Gly Gly  Ser Pro Met Thr Met  Asp Asn Phe Gly Lys  His Tyr Thr 
    1265                 1270                 1275             


Leu Asn  Ser Glu Ala Pro Leu  Tyr Val Gly Gly Met  Pro Val Asp 
    1280                 1285                 1290             


Val Asn  Ser Ala Ala Phe Arg  Leu Trp Gln Ile Leu  Asn Gly Thr 
    1295                 1300                 1305             


Gly Phe  His Gly Cys Ile Arg  Asn Leu Tyr Ile Asn  Asn Glu Leu 
    1310                 1315                 1320             


Gln Asp  Phe Thr Lys Thr Gln  Met Lys Pro Gly Val  Val Pro Gly 
    1325                 1330                 1335             


Cys Glu  Pro Cys Arg Lys Leu  Tyr Cys Leu His Gly  Ile Cys Gln 
    1340                 1345                 1350             


Pro Asn  Ala Thr Pro Gly Pro  Met Cys His Cys Glu  Ala Gly Trp 
    1355                 1360                 1365             


Val Gly  Leu His Cys Asp Gln  Pro Ala Asp Gly Pro  Cys His Gly 
    1370                 1375                 1380             


His Lys  Cys Val His Gly Gln  Cys Val Pro Leu Asp  Ala Leu Ser 
    1385                 1390                 1395             


Tyr Ser  Cys Gln Cys Gln Asp  Gly Tyr Ser Gly Ala  Leu Cys Asn 
    1400                 1405                 1410             


Gln Ala  Gly Ala Leu Ala Glu  Pro Cys Arg Gly Leu  Gln Cys Leu 
    1415                 1420                 1425             


His Gly  His Cys Gln Ala Ser  Gly Thr Lys Gly Ala  His Cys Val 
    1430                 1435                 1440             


Cys Asp  Pro Gly Phe Ser Gly  Glu Leu Cys Glu Gln  Glu Ser Glu 
    1445                 1450                 1455             


Cys Arg  Gly Asp Pro Val Arg  Asp Phe His Gln Val  Gln Arg Gly 
    1460                 1465                 1470             


Tyr Ala  Ile Cys Gln Thr Thr  Arg Pro Leu Ser Trp  Val Glu Cys 
    1475                 1480                 1485             


Arg Gly  Ser Cys Pro Gly Gln  Gly Cys Cys Gln Gly  Leu Arg Leu 
    1490                 1495                 1500             


Lys Arg  Arg Lys Phe Thr Phe  Glu Cys Ser Asp Gly  Thr Ser Phe 
    1505                 1510                 1515             


Ala Glu  Glu Val Glu Lys Pro  Thr Lys Cys Gly Cys  Ala Leu Cys 
    1520                 1525                 1530             


Ala 
    


<210>  4013
<211>  1194
<212>  PRT
<213>  homo sapiens

<400>  4013

Met Glu Thr Arg Arg Arg Leu Glu Gln Glu Arg Ala Thr Met Gln Met 
1               5                   10                  15      


Thr Pro Gly Glu Phe Arg Arg Pro Arg Leu Ala Ser Phe Gly Gly Met 
            20                  25                  30          


Gly Thr Thr Ser Ser Leu Pro Ser Phe Val Gly Ser Gly Asn His Asn 
        35                  40                  45              


Pro Ala Lys His Gln Leu Gln Asn Gly Tyr Gln Gly Asn Gly Asp Tyr 
    50                  55                  60                  


Gly Ser Tyr Ala Pro Ala Ala Pro Thr Thr Ser Ser Met Gly Ser Ser 
65                  70                  75                  80  


Ile Arg His Ser Pro Leu Ser Ser Gly Ile Ser Thr Pro Val Thr Asn 
                85                  90                  95      


Val Ser Pro Met His Leu Gln His Ile Arg Glu Gln Met Ala Ile Ala 
            100                 105                 110         


Leu Lys Arg Leu Lys Glu Leu Glu Glu Gln Val Arg Thr Ile Pro Val 
        115                 120                 125             


Leu Gln Val Lys Ile Ser Val Leu Gln Glu Glu Lys Arg Gln Leu Val 
    130                 135                 140                 


Ser Gln Leu Lys Asn Gln Arg Ala Ala Ser Gln Ile Asn Val Cys Gly 
145                 150                 155                 160 


Val Arg Lys Arg Ser Tyr Ser Ala Gly Asn Ala Ser Gln Leu Glu Gln 
                165                 170                 175     


Leu Ser Arg Ala Arg Arg Ser Gly Gly Glu Leu Tyr Ile Asp Tyr Glu 
            180                 185                 190         


Glu Glu Glu Met Glu Thr Val Glu Gln Ser Thr Gln Arg Ile Lys Glu 
        195                 200                 205             


Phe Arg Gln Leu Thr Ala Asp Met Gln Ala Leu Glu Gln Lys Ile Gln 
    210                 215                 220                 


Asp Ser Ser Cys Glu Ala Ser Ser Glu Leu Arg Glu Asn Gly Glu Cys 
225                 230                 235                 240 


Arg Ser Val Ala Val Gly Ala Glu Glu Asn Met Asn Asp Ile Val Val 
                245                 250                 255     


Tyr His Arg Gly Ser Arg Ser Cys Lys Asp Ala Ala Val Gly Thr Leu 
            260                 265                 270         


Val Glu Met Arg Asn Cys Gly Val Ser Val Thr Glu Ala Met Leu Gly 
        275                 280                 285             


Val Met Thr Glu Ala Asp Lys Glu Ile Glu Leu Gln Gln Gln Thr Ile 
    290                 295                 300                 


Glu Ser Leu Lys Glu Lys Ile Tyr Arg Leu Glu Val Gln Leu Arg Glu 
305                 310                 315                 320 


Thr Thr His Asp Arg Glu Met Thr Lys Leu Lys Gln Glu Leu Gln Ala 
                325                 330                 335     


Ala Gly Ser Arg Lys Lys Val Asp Lys Ala Thr Met Ala Gln Pro Leu 
            340                 345                 350         


Val Phe Ser Lys Val Val Glu Ala Val Val Gln Thr Arg Asp Gln Met 
        355                 360                 365             


Val Gly Ser His Met Asp Leu Val Asp Thr Cys Val Gly Thr Ser Val 
    370                 375                 380                 


Glu Thr Asn Ser Val Gly Ile Ser Cys Gln Pro Glu Cys Lys Asn Lys 
385                 390                 395                 400 


Val Val Gly Pro Glu Leu Pro Met Asn Trp Trp Ile Val Lys Glu Arg 
                405                 410                 415     


Val Glu Met His Asp Arg Cys Ala Gly Arg Ser Val Glu Met Cys Asp 
            420                 425                 430         


Lys Ser Val Ser Val Glu Val Ser Val Cys Glu Thr Gly Ser Asn Thr 
        435                 440                 445             


Glu Glu Ser Val Asn Asp Leu Thr Leu Leu Lys Thr Asn Leu Asn Leu 
    450                 455                 460                 


Lys Glu Val Arg Ser Ile Gly Cys Gly Asp Cys Ser Val Asp Val Thr 
465                 470                 475                 480 


Val Cys Ser Pro Lys Glu Cys Ala Ser Arg Gly Val Asn Thr Glu Ala 
                485                 490                 495     


Val Ser Gln Val Glu Ala Ala Val Met Ala Val Pro Arg Thr Ala Asp 
            500                 505                 510         


Gln Asp Thr Ser Thr Asp Leu Glu Gln Val His Gln Phe Thr Asn Thr 
        515                 520                 525             


Glu Thr Ala Thr Leu Ile Glu Ser Cys Thr Asn Thr Cys Leu Ser Thr 
    530                 535                 540                 


Leu Asp Lys Gln Thr Ser Thr Gln Thr Val Glu Thr Arg Thr Val Ala 
545                 550                 555                 560 


Val Gly Glu Gly Arg Val Lys Asp Ile Asn Ser Ser Thr Lys Thr Arg 
                565                 570                 575     


Ser Ile Gly Val Gly Thr Leu Leu Ser Gly His Ser Gly Phe Asp Arg 
            580                 585                 590         


Pro Ser Ala Val Lys Thr Lys Glu Ser Gly Val Gly Gln Ile Asn Ile 
        595                 600                 605             


Asn Asp Asn Tyr Leu Val Gly Leu Lys Met Arg Thr Ile Ala Cys Gly 
    610                 615                 620                 


Pro Pro Gln Leu Thr Val Gly Leu Thr Ala Ser Arg Arg Ser Val Gly 
625                 630                 635                 640 


Val Gly Asp Asp Pro Val Gly Glu Ser Leu Glu Asn Pro Gln Pro Gln 
                645                 650                 655     


Ala Pro Leu Gly Met Met Thr Gly Leu Asp His Tyr Ile Glu Arg Ile 
            660                 665                 670         


Gln Lys Leu Leu Ala Glu Gln Gln Thr Leu Leu Ala Glu Asn Tyr Ser 
        675                 680                 685             


Glu Leu Ala Glu Ala Phe Gly Glu Pro His Ser Gln Met Gly Ser Leu 
    690                 695                 700                 


Asn Ser Gln Leu Ile Ser Thr Leu Ser Ser Ile Asn Ser Val Met Lys 
705                 710                 715                 720 


Ser Ala Ser Thr Glu Glu Leu Arg Asn Pro Asp Phe Gln Lys Thr Ser 
                725                 730                 735     


Leu Gly Lys Ile Thr Gly Asn Tyr Leu Gly Tyr Thr Cys Lys Cys Gly 
            740                 745                 750         


Gly Leu Gln Ser Gly Ser Pro Leu Ser Ser Gln Thr Ser Gln Pro Glu 
        755                 760                 765             


Gln Glu Val Gly Thr Ser Glu Gly Lys Pro Ile Ser Ser Leu Asp Ala 
    770                 775                 780                 


Phe Pro Thr Gln Glu Gly Thr Leu Ser Pro Val Asn Leu Thr Asp Asp 
785                 790                 795                 800 


Gln Ile Ala Ala Gly Leu Tyr Ala Cys Thr Asn Asn Glu Ser Thr Leu 
                805                 810                 815     


Lys Ser Ile Met Lys Lys Lys Asp Gly Asn Lys Asp Ser Asn Gly Ala 
            820                 825                 830         


Lys Lys Asn Leu Gln Phe Val Gly Ile Asn Gly Gly Tyr Glu Thr Thr 
        835                 840                 845             


Ser Ser Asp Asp Ser Ser Ser Asp Glu Ser Ser Ser Ser Glu Ser Asp 
    850                 855                 860                 


Asp Glu Cys Asp Val Ile Glu Tyr Pro Leu Glu Glu Glu Glu Glu Glu 
865                 870                 875                 880 


Glu Asp Glu Asp Thr Arg Gly Met Ala Glu Gly His His Ala Val Asn 
                885                 890                 895     


Ile Glu Gly Leu Lys Ser Ala Arg Val Glu Asp Glu Met Gln Val Gln 
            900                 905                 910         


Glu Cys Glu Pro Glu Lys Val Glu Ile Arg Glu Arg Tyr Glu Leu Ser 
        915                 920                 925             


Glu Lys Met Leu Ser Ala Cys Asn Leu Leu Lys Asn Thr Ile Asn Asp 
    930                 935                 940                 


Pro Lys Ala Leu Thr Ser Lys Asp Met Arg Phe Cys Leu Asn Thr Leu 
945                 950                 955                 960 


Gln His Glu Trp Phe Arg Val Ser Ser Gln Lys Ser Ala Ile Pro Ala 
                965                 970                 975     


Met Val Gly Asp Tyr Ile Ala Ala Phe Glu Ala Ile Ser Pro Asp Val 
            980                 985                 990         


Leu Arg Tyr Val Ile Asn Leu Ala  Asp Gly Asn Gly Asn  Thr Ala Leu 
        995                 1000                 1005             


His Tyr  Ser Val Ser His Ser  Asn Phe Glu Ile Val  Lys Leu Leu 
    1010                 1015                 1020             


Leu Asp  Ala Asp Val Cys Asn  Val Asp His Gln Asn  Lys Ala Gly 
    1025                 1030                 1035             


Tyr Thr  Pro Ile Met Leu Ala  Ala Leu Ala Ala Val  Glu Ala Glu 
    1040                 1045                 1050             


Lys Asp  Met Arg Ile Val Glu  Glu Leu Phe Gly Cys  Gly Asp Val 
    1055                 1060                 1065             


Asn Ala  Lys Ala Ser Gln Ala  Gly Gln Thr Ala Leu  Met Leu Ala 
    1070                 1075                 1080             


Val Ser  His Gly Arg Ile Asp  Met Val Lys Gly Leu  Leu Ala Cys 
    1085                 1090                 1095             


Gly Ala  Asp Val Asn Ile Gln  Asp Asp Glu Gly Ser  Thr Ala Leu 
    1100                 1105                 1110             


Met Cys  Ala Ser Glu His Gly  His Val Glu Ile Val  Lys Leu Leu 
    1115                 1120                 1125             


Leu Ala  Gln Pro Gly Cys Asn  Gly His Leu Glu Asp  Asn Asp Gly 
    1130                 1135                 1140             


Ser Thr  Ala Leu Ser Ile Ala  Leu Glu Ala Gly His  Lys Asp Ile 
    1145                 1150                 1155             


Ala Val  Leu Leu Tyr Ala His  Val Asn Phe Ala Lys  Ala Gln Ser 
    1160                 1165                 1170             


Pro Gly  Thr Pro Arg Leu Gly  Arg Lys Thr Ser Pro  Gly Pro Thr 
    1175                 1180                 1185             


His Arg  Gly Ser Phe Asp 
    1190                 


<210>  4014
<211>  671
<212>  PRT
<213>  homo sapiens

<400>  4014

Met His His Gln Gln Arg Met Ala Ala Leu Gly Thr Asp Lys Glu Leu 
1               5                   10                  15      


Ser Asp Leu Leu Asp Phe Ser Ala Met Phe Ser Pro Pro Val Ser Ser 
            20                  25                  30          


Gly Lys Asn Gly Pro Thr Ser Leu Ala Ser Gly His Phe Thr Gly Ser 
        35                  40                  45              


Asn Val Glu Asp Arg Ser Ser Ser Gly Ser Trp Gly Asn Gly Gly His 
    50                  55                  60                  


Pro Ser Pro Ser Arg Asn Tyr Gly Asp Gly Thr Pro Tyr Asp His Met 
65                  70                  75                  80  


Thr Ser Arg Asp Leu Gly Ser His Asp Asn Leu Ser Pro Pro Phe Val 
                85                  90                  95      


Asn Ser Arg Ile Gln Ser Lys Thr Glu Arg Gly Ser Tyr Ser Ser Tyr 
            100                 105                 110         


Gly Arg Glu Ser Asn Leu Gln Gly Cys His Gln Gln Ser Leu Leu Gly 
        115                 120                 125             


Gly Asp Met Asp Met Gly Asn Pro Gly Thr Leu Ser Pro Thr Lys Pro 
    130                 135                 140                 


Gly Ser Gln Tyr Tyr Gln Tyr Ser Ser Asn Asn Pro Arg Arg Arg Pro 
145                 150                 155                 160 


Leu His Ser Ser Ala Met Glu Val Gln Thr Lys Lys Val Arg Lys Val 
                165                 170                 175     


Pro Pro Gly Leu Pro Ser Ser Val Tyr Ala Pro Ser Ala Ser Thr Ala 
            180                 185                 190         


Asp Tyr Asn Arg Asp Ser Pro Gly Tyr Pro Ser Ser Lys Pro Ala Thr 
        195                 200                 205             


Ser Thr Phe Pro Ser Ser Phe Phe Met Gln Asp Gly His His Ser Ser 
    210                 215                 220                 


Asp Pro Trp Ser Ser Ser Ser Gly Met Asn Gln Pro Gly Tyr Ala Gly 
225                 230                 235                 240 


Met Leu Gly Asn Ser Ser His Ile Pro Gln Ser Ser Ser Tyr Cys Ser 
                245                 250                 255     


Leu His Pro His Glu Arg Leu Ser Tyr Pro Ser His Ser Ser Ala Asp 
            260                 265                 270         


Ile Asn Ser Ser Leu Pro Pro Met Ser Thr Phe His Arg Ser Gly Thr 
        275                 280                 285             


Asn His Tyr Ser Thr Ser Ser Cys Thr Pro Pro Ala Asn Gly Thr Asp 
    290                 295                 300                 


Ser Ile Met Ala Asn Arg Gly Ser Gly Ala Ala Gly Ser Ser Gln Thr 
305                 310                 315                 320 


Gly Asp Ala Leu Gly Lys Ala Leu Ala Ser Ile Tyr Ser Pro Asp His 
                325                 330                 335     


Thr Asn Asn Ser Phe Ser Ser Asn Pro Ser Thr Pro Val Gly Ser Pro 
            340                 345                 350         


Pro Ser Leu Ser Ala Gly Thr Ala Val Trp Ser Arg Asn Gly Gly Gln 
        355                 360                 365             


Ala Ser Ser Ser Pro Asn Tyr Glu Gly Pro Leu His Ser Leu Gln Ser 
    370                 375                 380                 


Arg Ile Glu Asp Arg Leu Glu Arg Leu Asp Asp Ala Ile His Val Leu 
385                 390                 395                 400 


Arg Asn His Ala Val Gly Pro Ser Thr Ala Met Pro Gly Gly His Gly 
                405                 410                 415     


Asp Met His Gly Ile Ile Gly Pro Ser His Asn Gly Ala Met Gly Gly 
            420                 425                 430         


Leu Gly Ser Gly Tyr Gly Thr Gly Leu Leu Ser Ala Asn Arg His Ser 
        435                 440                 445             


Leu Met Val Gly Thr His Arg Glu Asp Gly Val Ala Leu Arg Gly Ser 
    450                 455                 460                 


His Ser Leu Leu Pro Asn Gln Val Pro Val Pro Gln Leu Pro Val Gln 
465                 470                 475                 480 


Ser Ala Thr Ser Pro Asp Leu Asn Pro Pro Gln Asp Pro Tyr Arg Gly 
                485                 490                 495     


Met Pro Pro Gly Leu Gln Gly Gln Ser Val Ser Ser Gly Ser Ser Glu 
            500                 505                 510         


Ile Lys Ser Asp Asp Glu Gly Asp Glu Asn Leu Gln Asp Thr Lys Ser 
        515                 520                 525             


Ser Glu Asp Lys Lys Leu Asp Asp Asp Lys Lys Asp Ile Lys Ser Ile 
    530                 535                 540                 


Thr Arg Ser Arg Ser Ser Asn Asn Asp Asp Glu Asp Leu Thr Pro Glu 
545                 550                 555                 560 


Gln Lys Ala Glu Arg Glu Lys Glu Arg Arg Met Ala Asn Asn Ala Arg 
                565                 570                 575     


Glu Arg Leu Arg Val Arg Asp Ile Asn Glu Ala Phe Lys Glu Leu Gly 
            580                 585                 590         


Arg Met Val Gln Leu His Leu Lys Ser Asp Lys Pro Gln Thr Lys Leu 
        595                 600                 605             


Leu Ile Leu His Gln Ala Val Ala Val Ile Leu Ser Leu Glu Gln Gln 
    610                 615                 620                 


Val Arg Glu Arg Asn Leu Asn Pro Lys Ala Ala Cys Leu Lys Arg Arg 
625                 630                 635                 640 


Glu Glu Glu Lys Val Ser Ser Glu Pro Pro Pro Leu Ser Leu Ala Gly 
                645                 650                 655     


Pro His Pro Gly Met Gly Asp Ala Ser Asn His Met Gly Gln Met 
            660                 665                 670     


<210>  4015
<211>  588
<212>  PRT
<213>  homo sapiens

<400>  4015

Met Pro Gln Leu Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ser Gly 
1               5                   10                  15      


Gly Gly Gly Gly Ser Ser Ala Gly Ala Ala Gly Gly Gly Asp Asp Leu 
            20                  25                  30          


Gly Ala Asn Asp Glu Leu Ile Pro Phe Gln Asp Glu Gly Gly Glu Glu 
        35                  40                  45              


Gln Glu Pro Ser Ser Asp Ser Ala Ser Ala Gln Arg Asp Leu Asp Glu 
    50                  55                  60                  


Val Lys Ser Ser Leu Val Asn Glu Ser Glu Asn Gln Ser Ser Ser Ser 
65                  70                  75                  80  


Asp Ser Glu Ala Glu Arg Arg Pro Gln Pro Val Arg Asp Thr Phe Gln 
                85                  90                  95      


Lys Pro Arg Asp Tyr Phe Ala Glu Val Arg Arg Pro Gln Asp Ser Ala 
            100                 105                 110         


Phe Phe Lys Gly Pro Pro Tyr Pro Gly Tyr Pro Phe Leu Met Ile Pro 
        115                 120                 125             


Asp Leu Ser Ser Pro Tyr Leu Ser Asn Gly Pro Leu Ser Pro Gly Gly 
    130                 135                 140                 


Ala Arg Thr Tyr Leu Gln Met Lys Trp Pro Leu Leu Asp Val Pro Ser 
145                 150                 155                 160 


Ser Ala Thr Val Lys Asp Thr Arg Ser Pro Ser Pro Ala His Leu Ser 
                165                 170                 175     


Asn Lys Val Pro Val Val Gln His Pro His His Met His Pro Leu Thr 
            180                 185                 190         


Pro Leu Ile Thr Tyr Ser Asn Asp His Phe Ser Pro Gly Ser Pro Pro 
        195                 200                 205             


Thr His Leu Ser Pro Glu Ile Asp Pro Lys Thr Gly Ile Pro Arg Pro 
    210                 215                 220                 


Pro His Pro Ser Glu Leu Ser Pro Tyr Tyr Pro Leu Ser Pro Gly Ala 
225                 230                 235                 240 


Val Gly Gln Ile Pro His Pro Leu Gly Trp Leu Val Pro Gln Gln Gly 
                245                 250                 255     


Gln Pro Met Tyr Ser Leu Pro Pro Gly Gly Phe Arg His Pro Tyr Pro 
            260                 265                 270         


Ala Leu Ala Met Asn Ala Ser Met Ser Ser Leu Val Ser Ser Arg Phe 
        275                 280                 285             


Ser Pro His Met Val Ala Pro Ala His Pro Gly Leu Pro Thr Ser Gly 
    290                 295                 300                 


Ile Pro His Pro Ala Ile Val Ser Pro Ile Val Lys Gln Glu Pro Ala 
305                 310                 315                 320 


Pro Pro Ser Leu Ser Pro Ala Val Ser Val Lys Ser Pro Val Thr Val 
                325                 330                 335     


Lys Lys Glu Glu Glu Lys Lys Pro His Val Lys Lys Pro Leu Asn Ala 
            340                 345                 350         


Phe Met Leu Tyr Met Lys Glu Met Arg Ala Lys Val Val Ala Glu Cys 
        355                 360                 365             


Thr Leu Lys Glu Ser Ala Ala Ile Asn Gln Ile Leu Gly Arg Lys Trp 
    370                 375                 380                 


His Asn Leu Ser Arg Glu Glu Gln Ala Lys Tyr Tyr Glu Leu Ala Arg 
385                 390                 395                 400 


Lys Glu Arg Gln Leu His Ser Gln Leu Tyr Pro Thr Trp Ser Ala Arg 
                405                 410                 415     


Asp Asn Tyr Gly Lys Lys Lys Lys Arg Lys Arg Glu Lys Gln Leu Ser 
            420                 425                 430         


Gln Thr Gln Ser Gln Gln Gln Val Gln Glu Ala Glu Gly Ala Leu Ala 
        435                 440                 445             


Ser Lys Ser Lys Lys Pro Cys Val Gln Tyr Leu Pro Pro Glu Lys Pro 
    450                 455                 460                 


Cys Asp Ser Pro Ala Ser Ser His Gly Ser Met Leu Asp Ser Pro Ala 
465                 470                 475                 480 


Thr Pro Ser Ala Ala Leu Ala Ser Pro Ala Ala Pro Ala Ala Thr His 
                485                 490                 495     


Ser Glu Gln Ala Gln Pro Leu Ser Leu Thr Thr Lys Pro Glu Thr Arg 
            500                 505                 510         


Ala Gln Leu Ala Leu His Ser Ala Ala Phe Leu Ser Ala Lys Ala Ala 
        515                 520                 525             


Ala Ser Ser Ser Gly Gln Met Gly Ser Gln Pro Pro Leu Leu Ser Arg 
    530                 535                 540                 


Pro Leu Pro Leu Gly Ser Met Pro Thr Ala Leu Leu Ala Ser Pro Pro 
545                 550                 555                 560 


Ser Phe Pro Ala Thr Leu His Ala His Gln Ala Leu Pro Val Leu Gln 
                565                 570                 575     


Ala Gln Pro Leu Ser Leu Val Thr Lys Ser Ala His 
            580                 585             


<210>  4016
<211>  426
<212>  PRT
<213>  homo sapiens

<400>  4016

Met Glu Pro Ser Ser Trp Ser Gly Ser Glu Ser Pro Ala Glu Asn Met 
1               5                   10                  15      


Glu Arg Met Ser Asp Ser Ala Asp Lys Pro Ile Asp Asn Asp Ala Glu 
            20                  25                  30          


Gly Val Trp Ser Pro Asp Ile Glu Gln Ser Phe Gln Glu Ala Leu Ala 
        35                  40                  45              


Ile Tyr Pro Pro Cys Gly Arg Arg Lys Ile Ile Leu Ser Asp Glu Gly 
    50                  55                  60                  


Lys Met Tyr Gly Arg Asn Glu Leu Ile Ala Arg Tyr Ile Lys Leu Arg 
65                  70                  75                  80  


Thr Gly Lys Thr Arg Thr Arg Lys Gln Val Ser Ser His Ile Gln Val 
                85                  90                  95      


Leu Ala Arg Arg Lys Ser Arg Asp Phe His Ser Lys Leu Lys Asp Gln 
            100                 105                 110         


Thr Ala Lys Asp Lys Ala Leu Gln His Met Ala Ala Met Ser Ser Ala 
        115                 120                 125             


Gln Ile Val Ser Ala Thr Ala Ile His Asn Lys Leu Gly Leu Pro Gly 
    130                 135                 140                 


Ile Pro Arg Pro Thr Phe Pro Gly Ala Pro Gly Phe Trp Pro Gly Met 
145                 150                 155                 160 


Ile Gln Thr Gly Gln Pro Gly Ser Ser Gln Asp Val Lys Pro Phe Val 
                165                 170                 175     


Gln Gln Ala Tyr Pro Ile Gln Pro Ala Val Thr Ala Pro Ile Pro Gly 
            180                 185                 190         


Phe Glu Pro Ala Ser Ala Pro Ala Pro Ser Val Pro Ala Trp Gln Gly 
        195                 200                 205             


Arg Ser Ile Gly Thr Thr Lys Leu Arg Leu Val Glu Phe Ser Ala Phe 
    210                 215                 220                 


Leu Glu Gln Gln Arg Asp Pro Asp Ser Tyr Asn Lys His Leu Phe Val 
225                 230                 235                 240 


His Ile Gly His Ala Asn His Ser Tyr Ser Asp Pro Leu Leu Glu Ser 
                245                 250                 255     


Val Asp Ile Arg Gln Ile Tyr Asp Lys Phe Pro Glu Lys Lys Gly Gly 
            260                 265                 270         


Leu Lys Glu Leu Phe Gly Lys Gly Pro Gln Asn Ala Phe Phe Leu Val 
        275                 280                 285             


Lys Phe Trp Ala Asp Leu Asn Cys Asn Ile Gln Asp Asp Ala Gly Ala 
    290                 295                 300                 


Phe Tyr Gly Val Thr Ser Gln Tyr Glu Ser Ser Glu Asn Met Thr Val 
305                 310                 315                 320 


Thr Cys Ser Thr Lys Val Cys Ser Phe Gly Lys Gln Val Val Glu Lys 
                325                 330                 335     


Val Glu Thr Glu Tyr Ala Arg Phe Glu Asn Gly Arg Phe Val Tyr Arg 
            340                 345                 350         


Ile Asn Arg Ser Pro Met Cys Glu Tyr Met Ile Asn Phe Ile His Lys 
        355                 360                 365             


Leu Lys His Leu Pro Glu Lys Tyr Met Met Asn Ser Val Leu Glu Asn 
    370                 375                 380                 


Phe Thr Ile Leu Leu Val Val Thr Asn Arg Asp Thr Gln Glu Thr Leu 
385                 390                 395                 400 


Leu Cys Met Ala Cys Val Phe Glu Val Ser Asn Ser Glu His Gly Ala 
                405                 410                 415     


Gln His His Ile Tyr Arg Leu Val Lys Asp 
            420                 425     


<210>  4017
<211>  447
<212>  PRT
<213>  homo sapiens

<400>  4017

Met Gly Glu Pro Arg Ala Gly Ala Ala Leu Asp Asp Gly Ser Gly Trp 
1               5                   10                  15      


Thr Gly Ser Glu Glu Gly Ser Glu Glu Gly Thr Gly Gly Ser Glu Gly 
            20                  25                  30          


Ala Gly Gly Asp Gly Gly Pro Asp Ala Glu Gly Val Trp Ser Pro Asp 
        35                  40                  45              


Ile Glu Gln Ser Phe Gln Glu Ala Leu Ala Ile Tyr Pro Pro Cys Gly 
    50                  55                  60                  


Arg Arg Lys Ile Ile Leu Ser Asp Glu Gly Lys Met Tyr Gly Arg Asn 
65                  70                  75                  80  


Glu Leu Ile Ala Arg Tyr Ile Lys Leu Arg Thr Gly Lys Thr Arg Thr 
                85                  90                  95      


Arg Lys Gln Val Ser Ser His Ile Gln Val Leu Ala Arg Arg Lys Ser 
            100                 105                 110         


Arg Glu Ile Gln Ser Lys Leu Lys Asp Gln Val Ser Lys Asp Lys Ala 
        115                 120                 125             


Phe Gln Thr Met Ala Thr Met Ser Ser Ala Gln Leu Ile Ser Ala Pro 
    130                 135                 140                 


Ser Leu Gln Ala Lys Leu Gly Pro Thr Gly Pro Gln Ala Ser Glu Leu 
145                 150                 155                 160 


Phe Gln Phe Trp Ser Gly Gly Ser Gly Pro Pro Trp Asn Val Pro Asp 
                165                 170                 175     


Val Lys Pro Phe Ser Gln Thr Pro Phe Thr Leu Ser Leu Thr Pro Pro 
            180                 185                 190         


Ser Thr Asp Leu Pro Gly Tyr Glu Pro Pro Gln Ala Leu Ser Pro Leu 
        195                 200                 205             


Pro Pro Pro Thr Pro Ser Pro Pro Ala Trp Gln Ala Arg Gly Leu Gly 
    210                 215                 220                 


Thr Ala Arg Leu Gln Leu Val Glu Phe Ser Ala Phe Val Glu Pro Pro 
225                 230                 235                 240 


Asp Ala Val Asp Ser Tyr Gln Arg His Leu Phe Val His Ile Ser Gln 
                245                 250                 255     


His Cys Pro Ser Pro Gly Ala Pro Pro Leu Glu Ser Val Asp Val Arg 
            260                 265                 270         


Gln Ile Tyr Asp Lys Phe Pro Glu Lys Lys Gly Gly Leu Arg Glu Leu 
        275                 280                 285             


Tyr Asp Arg Gly Pro Pro His Ala Phe Phe Leu Val Lys Phe Trp Ala 
    290                 295                 300                 


Asp Leu Asn Trp Gly Pro Ser Gly Glu Glu Ala Gly Ala Gly Gly Ser 
305                 310                 315                 320 


Ile Ser Ser Gly Gly Phe Tyr Gly Val Ser Ser Gln Tyr Glu Ser Leu 
                325                 330                 335     


Glu His Met Thr Leu Thr Cys Ser Ser Lys Val Cys Ser Phe Gly Lys 
            340                 345                 350         


Gln Val Val Glu Lys Val Glu Thr Glu Arg Ala Gln Leu Glu Asp Gly 
        355                 360                 365             


Arg Phe Val Tyr Arg Leu Leu Arg Ser Pro Met Cys Glu Tyr Leu Val 
    370                 375                 380                 


Asn Phe Leu His Lys Leu Arg Gln Leu Pro Glu Arg Tyr Met Met Asn 
385                 390                 395                 400 


Ser Val Leu Glu Asn Phe Thr Ile Leu Gln Val Val Thr Asn Arg Asp 
                405                 410                 415     


Thr Gln Glu Leu Leu Leu Cys Thr Ala Tyr Val Phe Glu Val Ser Thr 
            420                 425                 430         


Ser Glu Arg Gly Ala Gln His His Ile Tyr Arg Leu Val Arg Asp 
        435                 440                 445         


<210>  4018
<211>  303
<212>  PRT
<213>  homo sapiens

<400>  4018

Met Ser Asp Ala Gly Gly Gly Lys Lys Pro Pro Val Asp Pro Gln Ala 
1               5                   10                  15      


Gly Pro Gly Pro Gly Pro Gly Arg Ala Ala Gly Glu Arg Gly Leu Ser 
            20                  25                  30          


Gly Ser Phe Pro Leu Val Leu Lys Lys Leu Met Glu Asn Pro Pro Arg 
        35                  40                  45              


Glu Ala Arg Leu Asp Lys Glu Lys Gly Lys Glu Lys Leu Glu Glu Asp 
    50                  55                  60                  


Glu Ala Ala Ala Ala Ser Thr Met Ala Val Ser Ala Ser Leu Met Pro 
65                  70                  75                  80  


Pro Ile Trp Asp Lys Thr Ile Pro Tyr Asp Gly Glu Ser Phe His Leu 
                85                  90                  95      


Glu Tyr Met Asp Leu Asp Glu Phe Leu Leu Glu Asn Gly Ile Pro Ala 
            100                 105                 110         


Ser Pro Thr His Leu Ala His Asn Leu Leu Leu Pro Val Ala Glu Leu 
        115                 120                 125             


Glu Gly Lys Glu Ser Ala Ser Ser Ser Thr Ala Ser Pro Pro Ser Ser 
    130                 135                 140                 


Ser Thr Ala Ile Phe Gln Pro Ser Glu Thr Val Ser Ser Thr Glu Ser 
145                 150                 155                 160 


Ser Leu Glu Lys Glu Arg Glu Thr Pro Ser Pro Ile Asp Pro Asn Cys 
                165                 170                 175     


Val Glu Val Asp Val Asn Phe Asn Pro Asp Pro Ala Asp Leu Val Leu 
            180                 185                 190         


Ser Ser Val Pro Gly Gly Glu Leu Phe Asn Pro Arg Lys His Lys Phe 
        195                 200                 205             


Ala Glu Glu Asp Leu Lys Pro Gln Pro Met Ile Lys Lys Ala Lys Lys 
    210                 215                 220                 


Val Phe Val Pro Asp Glu Gln Lys Asp Glu Lys Tyr Trp Thr Arg Arg 
225                 230                 235                 240 


Lys Lys Asn Asn Val Ala Ala Lys Arg Ser Arg Asp Ala Arg Arg Leu 
                245                 250                 255     


Lys Glu Asn Gln Ile Thr Ile Arg Ala Ala Phe Leu Glu Lys Glu Asn 
            260                 265                 270         


Thr Ala Leu Arg Thr Glu Val Ala Glu Leu Arg Lys Glu Val Gly Lys 
        275                 280                 285             


Cys Lys Thr Ile Val Ser Lys Tyr Glu Thr Lys Tyr Gly Pro Leu 
    290                 295                 300             


<210>  4019
<211>  273
<212>  PRT
<213>  homo sapiens

<400>  4019

Met Asp Met Pro Glu Val Leu Lys Ser Leu Leu Glu His Ser Leu Pro 
1               5                   10                  15      


Trp Pro Glu Lys Arg Thr Asp Lys Glu Lys Gly Lys Glu Lys Leu Glu 
            20                  25                  30          


Glu Asp Glu Ala Ala Ala Ala Ser Thr Met Ala Val Ser Ala Ser Leu 
        35                  40                  45              


Met Pro Pro Ile Trp Asp Lys Thr Ile Pro Tyr Asp Gly Glu Ser Phe 
    50                  55                  60                  


His Leu Glu Tyr Met Asp Leu Asp Glu Phe Leu Leu Glu Asn Gly Ile 
65                  70                  75                  80  


Pro Ala Ser Pro Thr His Leu Ala His Asn Leu Leu Leu Pro Val Ala 
                85                  90                  95      


Glu Leu Glu Gly Lys Glu Ser Ala Ser Ser Ser Thr Ala Ser Pro Pro 
            100                 105                 110         


Ser Ser Ser Thr Ala Ile Phe Gln Pro Ser Glu Thr Val Ser Ser Thr 
        115                 120                 125             


Glu Ser Ser Leu Glu Lys Glu Arg Glu Thr Pro Ser Pro Ile Asp Pro 
    130                 135                 140                 


Asn Cys Val Glu Val Asp Val Asn Phe Asn Pro Asp Pro Ala Asp Leu 
145                 150                 155                 160 


Val Leu Ser Ser Val Pro Gly Gly Glu Leu Phe Asn Pro Arg Lys His 
                165                 170                 175     


Lys Phe Ala Glu Glu Asp Leu Lys Pro Gln Pro Met Ile Lys Lys Ala 
            180                 185                 190         


Lys Lys Val Phe Val Pro Asp Glu Gln Lys Asp Glu Lys Tyr Trp Thr 
        195                 200                 205             


Arg Arg Lys Lys Asn Asn Val Ala Ala Lys Arg Ser Arg Asp Ala Arg 
    210                 215                 220                 


Arg Leu Lys Glu Asn Gln Ile Thr Ile Arg Ala Ala Phe Leu Glu Lys 
225                 230                 235                 240 


Glu Asn Thr Ala Leu Arg Thr Glu Val Ala Glu Leu Arg Lys Glu Val 
                245                 250                 255     


Gly Lys Cys Lys Thr Ile Val Ser Lys Tyr Glu Thr Lys Tyr Gly Pro 
            260                 265                 270         


Leu 
    


<210>  4020
<211>  419
<212>  PRT
<213>  homo sapiens

<400>  4020

Met Ala Glu Asp Val Ser Ser Ala Ala Pro Ser Pro Arg Gly Cys Ala 
1               5                   10                  15      


Asp Gly Arg Asp Ala Asp Pro Thr Glu Glu Gln Met Ala Glu Thr Glu 
            20                  25                  30          


Arg Asn Asp Glu Glu Gln Phe Glu Cys Gln Glu Leu Leu Glu Cys Gln 
        35                  40                  45              


Val Gln Val Gly Ala Pro Glu Glu Glu Glu Glu Glu Glu Glu Asp Ala 
    50                  55                  60                  


Gly Leu Val Ala Glu Ala Glu Ala Val Ala Ala Gly Trp Met Leu Asp 
65                  70                  75                  80  


Phe Leu Cys Leu Ser Leu Cys Arg Ala Phe Arg Asp Gly Arg Ser Glu 
                85                  90                  95      


Asp Phe Arg Arg Thr Arg Asn Ser Ala Glu Ala Ile Ile His Gly Leu 
            100                 105                 110         


Ser Ser Leu Thr Ala Cys Gln Leu Arg Thr Ile Tyr Ile Cys Gln Phe 
        115                 120                 125             


Leu Thr Arg Ile Ala Ala Gly Lys Thr Leu Asp Ala Gln Phe Glu Asn 
    130                 135                 140                 


Asp Glu Arg Ile Thr Pro Leu Glu Ser Ala Leu Met Ile Trp Gly Ser 
145                 150                 155                 160 


Ile Glu Lys Glu His Asp Lys Leu His Glu Glu Ile Gln Asn Leu Ile 
                165                 170                 175     


Lys Ile Gln Ala Ile Ala Val Cys Met Glu Asn Gly Asn Phe Lys Glu 
            180                 185                 190         


Ala Glu Glu Val Phe Glu Arg Ile Phe Gly Asp Pro Asn Ser His Met 
        195                 200                 205             


Pro Phe Lys Ser Lys Leu Leu Met Ile Ile Ser Gln Lys Asp Thr Phe 
    210                 215                 220                 


His Ser Phe Phe Gln His Phe Ser Tyr Asn His Met Met Glu Lys Ile 
225                 230                 235                 240 


Lys Ser Tyr Val Asn Tyr Val Leu Ser Glu Lys Ser Ser Thr Phe Leu 
                245                 250                 255     


Met Lys Ala Ala Ala Lys Val Val Glu Ser Lys Arg Thr Arg Thr Ile 
            260                 265                 270         


Thr Ser Gln Asp Lys Pro Ser Gly Asn Asp Val Glu Met Glu Thr Glu 
        275                 280                 285             


Ala Asn Leu Asp Thr Arg Lys Arg Ser His Lys Asn Leu Phe Leu Ser 
    290                 295                 300                 


Lys Leu Gln His Gly Thr Gln Gln Gln Asp Leu Asn Lys Lys Glu Arg 
305                 310                 315                 320 


Arg Val Gly Thr Pro Gln Ser Thr Lys Lys Lys Lys Glu Ser Arg Arg 
                325                 330                 335     


Ala Thr Glu Ser Arg Ile Pro Val Ser Lys Ser Gln Pro Val Thr Pro 
            340                 345                 350         


Glu Lys His Arg Ala Arg Lys Arg Gln Ala Trp Leu Trp Glu Glu Asp 
        355                 360                 365             


Lys Asn Leu Arg Ser Gly Val Arg Lys Tyr Gly Glu Gly Asn Trp Ser 
    370                 375                 380                 


Lys Ile Leu Leu His Tyr Lys Phe Asn Asn Arg Thr Ser Val Met Leu 
385                 390                 395                 400 


Lys Asp Arg Trp Arg Thr Met Lys Lys Leu Lys Leu Ile Ser Ser Asp 
                405                 410                 415     


Ser Glu Asp 
            


<210>  4021
<211>  198
<212>  PRT
<213>  homo sapiens

<400>  4021

Met Ala Pro Thr Cys Val Phe Leu Ala Ser Lys Val Glu Glu Phe Gly 
1               5                   10                  15      


Val Val Ser Asn Thr Arg Leu Ile Ala Ala Ala Thr Ser Val Leu Lys 
            20                  25                  30          


Thr Arg Phe Ser Tyr Ala Phe Pro Lys Glu Phe Pro Tyr Arg Met Asn 
        35                  40                  45              


His Ile Leu Glu Cys Glu Phe Tyr Leu Leu Glu Leu Met Asp Cys Cys 
    50                  55                  60                  


Leu Ile Val Tyr His Pro Tyr Arg Pro Leu Leu Gln Tyr Val Gln Asp 
65                  70                  75                  80  


Met Gly Gln Glu Asp Met Leu Leu Pro Leu Ala Trp Arg Ile Val Asn 
                85                  90                  95      


Asp Thr Tyr Arg Thr Asp Leu Cys Leu Leu Tyr Pro Pro Phe Met Ile 
            100                 105                 110         


Ala Leu Ala Cys Leu His Val Ala Cys Val Val Gln Gln Lys Asp Ala 
        115                 120                 125             


Arg Gln Trp Phe Ala Glu Leu Ser Val Asp Met Glu Lys Ile Leu Glu 
    130                 135                 140                 


Ile Ile Arg Val Ile Leu Lys Leu Tyr Glu Gln Trp Lys Asn Phe Asp 
145                 150                 155                 160 


Glu Arg Lys Glu Met Ala Thr Ile Leu Ser Lys Met Pro Lys Pro Lys 
                165                 170                 175     


Pro Pro Pro Asn Ser Glu Gly Glu Gln Gly Pro Asn Gly Ser Gln Asn 
            180                 185                 190         


Ser Ser Tyr Ser Gln Ser 
        195             


<210>  4022
<211>  252
<212>  PRT
<213>  homo sapiens

<400>  4022

Met Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala Gly Ser Gly Lys Arg 
1               5                   10                  15      


Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val Gln Ile Leu Arg Asp 
            20                  25                  30          


Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro Ser Glu Gln Glu Lys 
        35                  40                  45              


Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr Leu Gln Val Cys Asn 
    50                  55                  60                  


Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro Asp Met Leu Arg Lys 
65                  70                  75                  80  


Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile Ser Arg Arg Gly Ala Lys 
                85                  90                  95      


Ile Ser Glu Thr Ser Ser Val Glu Ser Val Met Gly Ile Lys Asn Phe 
            100                 105                 110         


Met Pro Ala Leu Glu Glu Thr Pro Phe His Ser Cys Thr Ala Gly Pro 
        115                 120                 125             


Asn Pro Thr Leu Gly Arg Pro Leu Ser Pro Lys Pro Ser Ser Pro Gly 
    130                 135                 140                 


Ser Val Leu Ala Arg Pro Ser Val Ile Cys His Thr Thr Val Thr Ala 
145                 150                 155                 160 


Leu Lys Asp Val Pro Phe Ser Leu Cys Gln Ser Val Gly Val Gly Gln 
                165                 170                 175     


Asn Thr Asp Ile Gln Gln Ile Ala Ala Lys Asn Phe Thr Asp Thr Ser 
            180                 185                 190         


Leu Met Tyr Pro Glu Asp Thr Cys Lys Ser Gly Pro Ser Thr Asn Thr 
        195                 200                 205             


Gln Ser Gly Leu Phe Asn Thr Pro Pro Pro Thr Pro Pro Asp Leu Asn 
    210                 215                 220                 


Gln Asp Phe Ser Gly Phe Gln Leu Leu Val Asp Val Ala Leu Lys Arg 
225                 230                 235                 240 


Ala Ala Glu Met Glu Leu Gln Ala Lys Leu Thr Ala 
                245                 250         


<210>  4023
<211>  1170
<212>  PRT
<213>  homo sapiens

<400>  4023

Met Gly Leu Ala Trp Gly Leu Gly Val Leu Phe Leu Met His Val Cys 
1               5                   10                  15      


Gly Thr Asn Arg Ile Pro Glu Ser Gly Gly Asp Asn Ser Val Phe Asp 
            20                  25                  30          


Ile Phe Glu Leu Thr Gly Ala Ala Arg Lys Gly Ser Gly Arg Arg Leu 
        35                  40                  45              


Val Lys Gly Pro Asp Pro Ser Ser Pro Ala Phe Arg Ile Glu Asp Ala 
    50                  55                  60                  


Asn Leu Ile Pro Pro Val Pro Asp Asp Lys Phe Gln Asp Leu Val Asp 
65                  70                  75                  80  


Ala Val Arg Ala Glu Lys Gly Phe Leu Leu Leu Ala Ser Leu Arg Gln 
                85                  90                  95      


Met Lys Lys Thr Arg Gly Thr Leu Leu Ala Leu Glu Arg Lys Asp His 
            100                 105                 110         


Ser Gly Gln Val Phe Ser Val Val Ser Asn Gly Lys Ala Gly Thr Leu 
        115                 120                 125             


Asp Leu Ser Leu Thr Val Gln Gly Lys Gln His Val Val Ser Val Glu 
    130                 135                 140                 


Glu Ala Leu Leu Ala Thr Gly Gln Trp Lys Ser Ile Thr Leu Phe Val 
145                 150                 155                 160 


Gln Glu Asp Arg Ala Gln Leu Tyr Ile Asp Cys Glu Lys Met Glu Asn 
                165                 170                 175     


Ala Glu Leu Asp Val Pro Ile Gln Ser Val Phe Thr Arg Asp Leu Ala 
            180                 185                 190         


Ser Ile Ala Arg Leu Arg Ile Ala Lys Gly Gly Val Asn Asp Asn Phe 
        195                 200                 205             


Gln Gly Val Leu Gln Asn Val Arg Phe Val Phe Gly Thr Thr Pro Glu 
    210                 215                 220                 


Asp Ile Leu Arg Asn Lys Gly Cys Ser Ser Ser Thr Ser Val Leu Leu 
225                 230                 235                 240 


Thr Leu Asp Asn Asn Val Val Asn Gly Ser Ser Pro Ala Ile Arg Thr 
                245                 250                 255     


Asn Tyr Ile Gly His Lys Thr Lys Asp Leu Gln Ala Ile Cys Gly Ile 
            260                 265                 270         


Ser Cys Asp Glu Leu Ser Ser Met Val Leu Glu Leu Arg Gly Leu Arg 
        275                 280                 285             


Thr Ile Val Thr Thr Leu Gln Asp Ser Ile Arg Lys Val Thr Glu Glu 
    290                 295                 300                 


Asn Lys Glu Leu Ala Asn Glu Leu Arg Arg Pro Pro Leu Cys Tyr His 
305                 310                 315                 320 


Asn Gly Val Gln Tyr Arg Asn Asn Glu Glu Trp Thr Val Asp Ser Cys 
                325                 330                 335     


Thr Glu Cys His Cys Gln Asn Ser Val Thr Ile Cys Lys Lys Val Ser 
            340                 345                 350         


Cys Pro Ile Met Pro Cys Ser Asn Ala Thr Val Pro Asp Gly Glu Cys 
        355                 360                 365             


Cys Pro Arg Cys Trp Pro Ser Asp Ser Ala Asp Asp Gly Trp Ser Pro 
    370                 375                 380                 


Trp Ser Glu Trp Thr Ser Cys Ser Thr Ser Cys Gly Asn Gly Ile Gln 
385                 390                 395                 400 


Gln Arg Gly Arg Ser Cys Asp Ser Leu Asn Asn Arg Cys Glu Gly Ser 
                405                 410                 415     


Ser Val Gln Thr Arg Thr Cys His Ile Gln Glu Cys Asp Lys Arg Phe 
            420                 425                 430         


Lys Gln Asp Gly Gly Trp Ser His Trp Ser Pro Trp Ser Ser Cys Ser 
        435                 440                 445             


Val Thr Cys Gly Asp Gly Val Ile Thr Arg Ile Arg Leu Cys Asn Ser 
    450                 455                 460                 


Pro Ser Pro Gln Met Asn Gly Lys Pro Cys Glu Gly Glu Ala Arg Glu 
465                 470                 475                 480 


Thr Lys Ala Cys Lys Lys Asp Ala Cys Pro Ile Asn Gly Gly Trp Gly 
                485                 490                 495     


Pro Trp Ser Pro Trp Asp Ile Cys Ser Val Thr Cys Gly Gly Gly Val 
            500                 505                 510         


Gln Lys Arg Ser Arg Leu Cys Asn Asn Pro Thr Pro Gln Phe Gly Gly 
        515                 520                 525             


Lys Asp Cys Val Gly Asp Val Thr Glu Asn Gln Ile Cys Asn Lys Gln 
    530                 535                 540                 


Asp Cys Pro Ile Asp Gly Cys Leu Ser Asn Pro Cys Phe Ala Gly Val 
545                 550                 555                 560 


Lys Cys Thr Ser Tyr Pro Asp Gly Ser Trp Lys Cys Gly Ala Cys Pro 
                565                 570                 575     


Pro Gly Tyr Ser Gly Asn Gly Ile Gln Cys Thr Asp Val Asp Glu Cys 
            580                 585                 590         


Lys Glu Val Pro Asp Ala Cys Phe Asn His Asn Gly Glu His Arg Cys 
        595                 600                 605             


Glu Asn Thr Asp Pro Gly Tyr Asn Cys Leu Pro Cys Pro Pro Arg Phe 
    610                 615                 620                 


Thr Gly Ser Gln Pro Phe Gly Gln Gly Val Glu His Ala Thr Ala Asn 
625                 630                 635                 640 


Lys Gln Val Cys Lys Pro Arg Asn Pro Cys Thr Asp Gly Thr His Asp 
                645                 650                 655     


Cys Asn Lys Asn Ala Lys Cys Asn Tyr Leu Gly His Tyr Ser Asp Pro 
            660                 665                 670         


Met Tyr Arg Cys Glu Cys Lys Pro Gly Tyr Ala Gly Asn Gly Ile Ile 
        675                 680                 685             


Cys Gly Glu Asp Thr Asp Leu Asp Gly Trp Pro Asn Glu Asn Leu Val 
    690                 695                 700                 


Cys Val Ala Asn Ala Thr Tyr His Cys Lys Lys Asp Asn Cys Pro Asn 
705                 710                 715                 720 


Leu Pro Asn Ser Gly Gln Glu Asp Tyr Asp Lys Asp Gly Ile Gly Asp 
                725                 730                 735     


Ala Cys Asp Asp Asp Asp Asp Asn Asp Lys Ile Pro Asp Asp Arg Asp 
            740                 745                 750         


Asn Cys Pro Phe His Tyr Asn Pro Ala Gln Tyr Asp Tyr Asp Arg Asp 
        755                 760                 765             


Asp Val Gly Asp Arg Cys Asp Asn Cys Pro Tyr Asn His Asn Pro Asp 
    770                 775                 780                 


Gln Ala Asp Thr Asp Asn Asn Gly Glu Gly Asp Ala Cys Ala Ala Asp 
785                 790                 795                 800 


Ile Asp Gly Asp Gly Ile Leu Asn Glu Arg Asp Asn Cys Gln Tyr Val 
                805                 810                 815     


Tyr Asn Val Asp Gln Arg Asp Thr Asp Met Asp Gly Val Gly Asp Gln 
            820                 825                 830         


Cys Asp Asn Cys Pro Leu Glu His Asn Pro Asp Gln Leu Asp Ser Asp 
        835                 840                 845             


Ser Asp Arg Ile Gly Asp Thr Cys Asp Asn Asn Gln Asp Ile Asp Glu 
    850                 855                 860                 


Asp Gly His Gln Asn Asn Leu Asp Asn Cys Pro Tyr Val Pro Asn Ala 
865                 870                 875                 880 


Asn Gln Ala Asp His Asp Lys Asp Gly Lys Gly Asp Ala Cys Asp His 
                885                 890                 895     


Asp Asp Asp Asn Asp Gly Ile Pro Asp Asp Lys Asp Asn Cys Arg Leu 
            900                 905                 910         


Val Pro Asn Pro Asp Gln Lys Asp Ser Asp Gly Asp Gly Arg Gly Asp 
        915                 920                 925             


Ala Cys Lys Asp Asp Phe Asp His Asp Ser Val Pro Asp Ile Asp Asp 
    930                 935                 940                 


Ile Cys Pro Glu Asn Val Asp Ile Ser Glu Thr Asp Phe Arg Arg Phe 
945                 950                 955                 960 


Gln Met Ile Pro Leu Asp Pro Lys Gly Thr Ser Gln Asn Asp Pro Asn 
                965                 970                 975     


Trp Val Val Arg His Gln Gly Lys Glu Leu Val Gln Thr Val Asn Cys 
            980                 985                 990         


Asp Pro Gly Leu Ala Val Gly Tyr  Asp Glu Phe Asn Ala  Val Asp Phe 
        995                 1000                 1005             


Ser Gly  Thr Phe Phe Ile Asn  Thr Glu Arg Asp Asp  Asp Tyr Ala 
    1010                 1015                 1020             


Gly Phe  Val Phe Gly Tyr Gln  Ser Ser Ser Arg Phe  Tyr Val Val 
    1025                 1030                 1035             


Met Trp  Lys Gln Val Thr Gln  Ser Tyr Trp Asp Thr  Asn Pro Thr 
    1040                 1045                 1050             


Arg Ala  Gln Gly Tyr Ser Gly  Leu Ser Val Lys Val  Val Asn Ser 
    1055                 1060                 1065             


Thr Thr  Gly Pro Gly Glu His  Leu Arg Asn Ala Leu  Trp His Thr 
    1070                 1075                 1080             


Gly Asn  Thr Pro Gly Gln Val  Arg Thr Leu Trp His  Asp Pro Arg 
    1085                 1090                 1095             


His Ile  Gly Trp Lys Asp Phe  Thr Ala Tyr Arg Trp  Arg Leu Ser 
    1100                 1105                 1110             


His Arg  Pro Lys Thr Gly Phe  Ile Arg Val Val Met  Tyr Glu Gly 
    1115                 1120                 1125             


Lys Lys  Ile Met Ala Asp Ser  Gly Pro Ile Tyr Asp  Lys Thr Tyr 
    1130                 1135                 1140             


Ala Gly  Gly Arg Leu Gly Leu  Phe Val Phe Ser Gln  Glu Met Val 
    1145                 1150                 1155             


Phe Phe  Ser Asp Leu Lys Tyr  Glu Cys Arg Asp Pro  
    1160                 1165                 1170 


<210>  4024
<211>  490
<212>  PRT
<213>  homo sapiens

<400>  4024

Met Glu Gln Lys Pro Ser Lys Val Glu Cys Gly Ser Asp Pro Glu Glu 
1               5                   10                  15      


Asn Ser Ala Arg Ser Pro Asp Gly Lys Arg Lys Arg Lys Asn Gly Gln 
            20                  25                  30          


Cys Ser Leu Lys Thr Ser Met Ser Gly Tyr Ile Pro Ser Tyr Leu Asp 
        35                  40                  45              


Lys Asp Glu Gln Cys Val Val Cys Gly Asp Lys Ala Thr Gly Tyr His 
    50                  55                  60                  


Tyr Arg Cys Ile Thr Cys Glu Gly Cys Lys Gly Phe Phe Arg Arg Thr 
65                  70                  75                  80  


Ile Gln Lys Asn Leu His Pro Thr Tyr Ser Cys Lys Tyr Asp Ser Cys 
                85                  90                  95      


Cys Val Ile Asp Lys Ile Thr Arg Asn Gln Cys Gln Leu Cys Arg Phe 
            100                 105                 110         


Lys Lys Cys Ile Ala Val Gly Met Ala Met Asp Leu Val Leu Asp Asp 
        115                 120                 125             


Ser Lys Arg Val Ala Lys Arg Lys Leu Ile Glu Gln Asn Arg Glu Arg 
    130                 135                 140                 


Arg Arg Lys Glu Glu Met Ile Arg Ser Leu Gln Gln Arg Pro Glu Pro 
145                 150                 155                 160 


Thr Pro Glu Glu Trp Asp Leu Ile His Ile Ala Thr Glu Ala His Arg 
                165                 170                 175     


Ser Thr Asn Ala Gln Gly Ser His Trp Lys Gln Arg Arg Lys Phe Leu 
            180                 185                 190         


Pro Asp Asp Ile Gly Gln Ser Pro Ile Val Ser Met Pro Asp Gly Asp 
        195                 200                 205             


Lys Val Asp Leu Glu Ala Phe Ser Glu Phe Thr Lys Ile Ile Thr Pro 
    210                 215                 220                 


Ala Ile Thr Arg Val Val Asp Phe Ala Lys Lys Leu Pro Met Phe Ser 
225                 230                 235                 240 


Glu Leu Pro Cys Glu Asp Gln Ile Ile Leu Leu Lys Gly Cys Cys Met 
                245                 250                 255     


Glu Ile Met Ser Leu Arg Ala Ala Val Arg Tyr Asp Pro Glu Ser Asp 
            260                 265                 270         


Thr Leu Thr Leu Ser Gly Glu Met Ala Val Lys Arg Glu Gln Leu Lys 
        275                 280                 285             


Asn Gly Gly Leu Gly Val Val Ser Asp Ala Ile Phe Glu Leu Gly Lys 
    290                 295                 300                 


Ser Leu Ser Ala Phe Asn Leu Asp Asp Thr Glu Val Ala Leu Leu Gln 
305                 310                 315                 320 


Ala Val Leu Leu Met Ser Thr Asp Arg Ser Gly Leu Leu Cys Val Asp 
                325                 330                 335     


Lys Ile Glu Lys Ser Gln Glu Ala Tyr Leu Leu Ala Phe Glu His Tyr 
            340                 345                 350         


Val Asn His Arg Lys His Asn Ile Pro His Phe Trp Pro Lys Leu Leu 
        355                 360                 365             


Met Lys Glu Arg Glu Val Gln Ser Ser Ile Leu Tyr Lys Gly Ala Ala 
    370                 375                 380                 


Ala Glu Gly Arg Pro Gly Gly Ser Leu Gly Val His Pro Glu Gly Gln 
385                 390                 395                 400 


Gln Leu Leu Gly Met His Val Val Gln Gly Pro Gln Val Arg Gln Leu 
                405                 410                 415     


Glu Gln Gln Leu Gly Glu Ala Gly Ser Leu Gln Gly Pro Val Leu Gln 
            420                 425                 430         


His Gln Ser Pro Lys Ser Pro Gln Gln Arg Leu Leu Glu Leu Leu His 
        435                 440                 445             


Arg Ser Gly Ile Leu His Ala Arg Ala Val Cys Gly Glu Asp Asp Ser 
    450                 455                 460                 


Ser Glu Ala Asp Ser Pro Ser Ser Ser Glu Glu Glu Pro Glu Val Cys 
465                 470                 475                 480 


Glu Asp Leu Ala Gly Asn Ala Ala Ser Pro 
                485                 490 


<210>  4025
<211>  385
<212>  PRT
<213>  homo sapiens

<400>  4025

Met Ala Arg Glu Asn Gly Glu Ser Ser Ser Ser Trp Lys Lys Gln Ala 
1               5                   10                  15      


Glu Asp Ile Lys Lys Ile Phe Glu Phe Lys Glu Thr Leu Gly Thr Gly 
            20                  25                  30          


Ala Phe Ser Glu Val Val Leu Ala Glu Glu Lys Ala Thr Gly Lys Leu 
        35                  40                  45              


Phe Ala Val Lys Cys Ile Pro Lys Lys Ala Leu Lys Gly Lys Glu Ser 
    50                  55                  60                  


Ser Ile Glu Asn Glu Ile Ala Val Leu Arg Lys Ile Lys His Glu Asn 
65                  70                  75                  80  


Ile Val Ala Leu Glu Asp Ile Tyr Glu Ser Pro Asn His Leu Tyr Leu 
                85                  90                  95      


Val Met Gln Leu Val Ser Gly Gly Glu Leu Phe Asp Arg Ile Val Glu 
            100                 105                 110         


Lys Gly Phe Tyr Thr Glu Lys Asp Ala Ser Thr Leu Ile Arg Gln Val 
        115                 120                 125             


Leu Asp Ala Val Tyr Tyr Leu His Arg Met Gly Ile Val His Arg Asp 
    130                 135                 140                 


Leu Lys Pro Glu Asn Leu Leu Tyr Tyr Ser Gln Asp Glu Glu Ser Lys 
145                 150                 155                 160 


Ile Met Ile Ser Asp Phe Gly Leu Ser Lys Met Glu Gly Lys Gly Asp 
                165                 170                 175     


Val Met Ser Thr Ala Cys Gly Thr Pro Gly Tyr Val Ala Pro Glu Val 
            180                 185                 190         


Leu Ala Gln Lys Pro Tyr Ser Lys Ala Val Asp Cys Trp Ser Ile Gly 
        195                 200                 205             


Val Ile Ala Tyr Ile Leu Leu Cys Gly Tyr Pro Pro Phe Tyr Asp Glu 
    210                 215                 220                 


Asn Asp Ser Lys Leu Phe Glu Gln Ile Leu Lys Ala Glu Tyr Glu Phe 
225                 230                 235                 240 


Asp Ser Pro Tyr Trp Asp Asp Ile Ser Asp Ser Ala Lys Asp Phe Ile 
                245                 250                 255     


Arg Asn Leu Met Glu Lys Asp Pro Asn Lys Arg Tyr Thr Cys Glu Gln 
            260                 265                 270         


Ala Ala Arg His Pro Trp Ile Ala Gly Asp Thr Ala Leu Asn Lys Asn 
        275                 280                 285             


Ile His Glu Ser Val Ser Ala Gln Ile Arg Lys Asn Phe Ala Lys Ser 
    290                 295                 300                 


Lys Trp Arg Gln Ala Phe Asn Ala Thr Ala Val Val Arg His Met Arg 
305                 310                 315                 320 


Lys Leu His Leu Gly Ser Ser Leu Asp Ser Ser Asn Ala Ser Val Ser 
                325                 330                 335     


Ser Ser Leu Ser Leu Ala Ser Gln Lys Asp Cys Leu Ala Pro Ser Thr 
            340                 345                 350         


Leu Cys Ser Phe Ile Ser Ser Ser Ser Gly Val Ser Gly Val Gly Ala 
        355                 360                 365             


Glu Arg Arg Pro Arg Pro Thr Thr Val Thr Ala Val His Ser Gly Ser 
    370                 375                 380                 


Lys 
385 


<210>  4026
<211>  733
<212>  PRT
<213>  homo sapiens

<400>  4026

Met Ala Glu Val Gly Glu Asp Ser Gly Ala Arg Ala Leu Leu Ala Leu 
1               5                   10                  15      


Arg Ser Ala Pro Cys Ser Pro Val Leu Cys Ala Ala Ala Ala Ala Ala 
            20                  25                  30          


Ala Phe Pro Ala Ala Ala Pro Pro Pro Ala Pro Ala Gln Pro Gln Pro 
        35                  40                  45              


Pro Pro Gly Pro Pro Pro Pro Pro Pro Pro Pro Leu Pro Pro Gly Ala 
    50                  55                  60                  


Ile Ala Gly Ala Gly Ser Ser Gly Gly Ser Ser Gly Val Ser Gly Asp 
65                  70                  75                  80  


Ser Ala Val Ala Gly Ala Ala Pro Ala Leu Val Ala Ala Ala Ala Ala 
                85                  90                  95      


Ser Val Arg Gln Ser Pro Gly Pro Ala Leu Ala Arg Leu Glu Gly Arg 
            100                 105                 110         


Glu Phe Glu Phe Leu Met Arg Gln Pro Ser Val Thr Ile Gly Arg Asn 
        115                 120                 125             


Ser Ser Gln Gly Ser Val Asp Leu Ser Met Gly Leu Ser Ser Phe Ile 
    130                 135                 140                 


Ser Arg Arg His Leu Gln Leu Ser Phe Gln Glu Pro His Phe Tyr Leu 
145                 150                 155                 160 


Arg Cys Leu Gly Lys Asn Gly Val Phe Val Asp Gly Ala Phe Gln Arg 
                165                 170                 175     


Arg Gly Ala Pro Ala Leu Gln Leu Pro Lys Gln Cys Thr Phe Arg Phe 
            180                 185                 190         


Pro Ser Thr Ala Ile Lys Ile Gln Phe Thr Ser Leu Tyr His Lys Glu 
        195                 200                 205             


Glu Ala Pro Ala Ser Pro Leu Arg Pro Leu Tyr Pro Gln Ile Ser Pro 
    210                 215                 220                 


Leu Lys Ile His Ile Pro Glu Pro Asp Leu Arg Ser Met Val Ser Pro 
225                 230                 235                 240 


Val Pro Ser Pro Thr Gly Thr Ile Ser Val Pro Asn Ser Cys Pro Ala 
                245                 250                 255     


Ser Pro Arg Gly Ala Gly Ser Ser Ser Tyr Arg Phe Val Gln Asn Val 
            260                 265                 270         


Thr Ser Asp Leu Gln Leu Ala Ala Glu Phe Ala Ala Lys Ala Ala Ser 
        275                 280                 285             


Glu Gln Gln Ala Asp Thr Ser Gly Gly Asp Ser Pro Lys Asp Glu Ser 
    290                 295                 300                 


Lys Pro Pro Phe Ser Tyr Ala Gln Leu Ile Val Gln Ala Ile Ser Ser 
305                 310                 315                 320 


Ala Gln Asp Arg Gln Leu Thr Leu Ser Gly Ile Tyr Ala His Ile Thr 
                325                 330                 335     


Lys His Tyr Pro Tyr Tyr Arg Thr Ala Asp Lys Gly Trp Gln Asn Ser 
            340                 345                 350         


Ile Arg His Asn Leu Ser Leu Asn Arg Tyr Phe Ile Lys Val Pro Arg 
        355                 360                 365             


Ser Gln Glu Glu Pro Gly Lys Gly Ser Phe Trp Arg Ile Asp Pro Ala 
    370                 375                 380                 


Ser Glu Ala Lys Leu Val Glu Gln Ala Phe Arg Lys Arg Arg Gln Arg 
385                 390                 395                 400 


Gly Val Ser Cys Phe Arg Thr Pro Phe Gly Pro Leu Ser Ser Arg Ser 
                405                 410                 415     


Ala Pro Ala Ser Pro Thr His Pro Gly Leu Met Ser Pro Arg Ser Gly 
            420                 425                 430         


Gly Leu Gln Thr Pro Glu Cys Leu Ser Arg Glu Gly Ser Pro Ile Pro 
        435                 440                 445             


His Asp Pro Glu Phe Gly Ser Lys Leu Ala Ser Val Pro Glu Tyr Arg 
    450                 455                 460                 


Tyr Ser Gln Ser Ala Pro Gly Ser Pro Val Ser Ala Gln Pro Val Ile 
465                 470                 475                 480 


Met Ala Val Pro Pro Arg Pro Ser Ser Leu Val Ala Lys Pro Val Ala 
                485                 490                 495     


Tyr Met Pro Ala Ser Ile Val Thr Ser Gln Gln Pro Ala Gly His Ala 
            500                 505                 510         


Ile His Val Val Gln Gln Ala Pro Thr Val Thr Met Val Arg Val Val 
        515                 520                 525             


Thr Thr Ser Ala Asn Ser Ala Asn Gly Tyr Ile Leu Thr Ser Gln Gly 
    530                 535                 540                 


Ala Ala Gly Gly Ser His Asp Ala Ala Gly Ala Ala Val Leu Asp Leu 
545                 550                 555                 560 


Gly Ser Glu Ala Arg Gly Leu Glu Glu Lys Pro Thr Ile Ala Phe Ala 
                565                 570                 575     


Thr Ile Pro Ala Ala Gly Gly Val Ile Gln Thr Val Ala Ser Gln Met 
            580                 585                 590         


Ala Pro Gly Val Pro Gly His Thr Val Thr Ile Leu Gln Pro Ala Thr 
        595                 600                 605             


Pro Val Thr Leu Gly Gln His His Leu Pro Val Arg Ala Val Thr Gln 
    610                 615                 620                 


Asn Gly Lys His Ala Val Pro Thr Asn Ser Leu Ala Gly Asn Ala Tyr 
625                 630                 635                 640 


Ala Leu Thr Ser Pro Leu Gln Leu Leu Ala Thr Gln Ala Ser Ser Ser 
                645                 650                 655     


Ala Pro Val Val Val Thr Arg Val Cys Glu Val Gly Pro Lys Glu Pro 
            660                 665                 670         


Ala Ala Ala Val Ala Ala Thr Ala Thr Thr Thr Pro Ala Thr Ala Thr 
        675                 680                 685             


Thr Ala Ser Ala Ser Ala Ser Ser Thr Gly Glu Pro Glu Val Lys Arg 
    690                 695                 700                 


Ser Arg Val Glu Glu Pro Ser Gly Ala Val Thr Thr Pro Ala Gly Val 
705                 710                 715                 720 


Ile Ala Ala Ala Gly Pro Gln Gly Pro Gly Thr Gly Glu 
                725                 730             


<210>  4027
<211>  748
<212>  PRT
<213>  homo sapiens

<400>  4027

Met Lys Thr Ser Pro Arg Arg Pro Leu Ile Leu Lys Arg Arg Arg Leu 
1               5                   10                  15      


Pro Leu Pro Val Gln Asn Ala Pro Ser Glu Thr Ser Glu Glu Glu Pro 
            20                  25                  30          


Lys Arg Ser Pro Ala Gln Gln Glu Ser Asn Gln Ala Glu Ala Ser Lys 
        35                  40                  45              


Glu Val Ala Glu Ser Asn Ser Cys Lys Phe Pro Ala Gly Ile Lys Ile 
    50                  55                  60                  


Ile Asn His Pro Thr Met Pro Asn Thr Gln Val Val Ala Ile Pro Asn 
65                  70                  75                  80  


Asn Ala Asn Ile His Ser Ile Ile Thr Ala Leu Thr Ala Lys Gly Lys 
                85                  90                  95      


Glu Ser Gly Ser Ser Gly Pro Asn Lys Phe Ile Leu Ile Ser Cys Gly 
            100                 105                 110         


Gly Ala Pro Thr Gln Pro Pro Gly Leu Arg Pro Gln Thr Gln Thr Ser 
        115                 120                 125             


Tyr Asp Ala Lys Arg Thr Glu Val Thr Leu Glu Thr Leu Gly Pro Lys 
    130                 135                 140                 


Pro Ala Ala Arg Asp Val Asn Leu Pro Arg Pro Pro Gly Ala Leu Cys 
145                 150                 155                 160 


Glu Gln Lys Arg Glu Thr Cys Ala Asp Gly Glu Ala Ala Gly Cys Thr 
                165                 170                 175     


Ile Asn Asn Ser Leu Ser Asn Ile Gln Trp Leu Arg Lys Met Ser Ser 
            180                 185                 190         


Asp Gly Leu Gly Ser Arg Ser Ile Lys Gln Glu Met Glu Glu Lys Glu 
        195                 200                 205             


Asn Cys His Leu Glu Gln Arg Gln Val Lys Val Glu Glu Pro Ser Arg 
    210                 215                 220                 


Pro Ser Ala Ser Trp Gln Asn Ser Val Ser Glu Arg Pro Pro Tyr Ser 
225                 230                 235                 240 


Tyr Met Ala Met Ile Gln Phe Ala Ile Asn Ser Thr Glu Arg Lys Arg 
                245                 250                 255     


Met Thr Leu Lys Asp Ile Tyr Thr Trp Ile Glu Asp His Phe Pro Tyr 
            260                 265                 270         


Phe Lys His Ile Ala Lys Pro Gly Trp Lys Asn Ser Ile Arg His Asn 
        275                 280                 285             


Leu Ser Leu His Asp Met Phe Val Arg Glu Thr Ser Ala Asn Gly Lys 
    290                 295                 300                 


Val Ser Phe Trp Thr Ile His Pro Ser Ala Asn Arg Tyr Leu Thr Leu 
305                 310                 315                 320 


Asp Gln Val Phe Lys Gln Gln Lys Arg Pro Asn Pro Glu Leu Arg Arg 
                325                 330                 335     


Asn Met Thr Ile Lys Thr Glu Leu Pro Leu Gly Ala Arg Arg Lys Met 
            340                 345                 350         


Lys Pro Leu Leu Pro Arg Val Ser Ser Tyr Leu Val Pro Ile Gln Phe 
        355                 360                 365             


Pro Val Asn Gln Ser Leu Val Leu Gln Pro Ser Val Lys Val Pro Leu 
    370                 375                 380                 


Pro Leu Ala Ala Ser Leu Met Ser Ser Glu Leu Ala Arg His Ser Lys 
385                 390                 395                 400 


Arg Val Arg Ile Ala Pro Lys Val Leu Leu Ala Glu Glu Gly Ile Ala 
                405                 410                 415     


Pro Leu Ser Ser Ala Gly Pro Gly Lys Glu Glu Lys Leu Leu Phe Gly 
            420                 425                 430         


Glu Gly Phe Ser Pro Leu Leu Pro Val Gln Thr Ile Lys Glu Glu Glu 
        435                 440                 445             


Ile Gln Pro Gly Glu Glu Met Pro His Leu Ala Arg Pro Ile Lys Val 
    450                 455                 460                 


Glu Ser Pro Pro Leu Glu Glu Trp Pro Ser Pro Ala Pro Ser Phe Lys 
465                 470                 475                 480 


Glu Glu Ser Ser His Ser Trp Glu Asp Ser Ser Gln Ser Pro Thr Pro 
                485                 490                 495     


Arg Pro Lys Lys Ser Tyr Ser Gly Leu Arg Ser Pro Thr Arg Cys Val 
            500                 505                 510         


Ser Glu Met Leu Val Ile Gln His Arg Glu Arg Arg Glu Arg Ser Arg 
        515                 520                 525             


Ser Arg Arg Lys Gln His Leu Leu Pro Pro Cys Val Asp Glu Pro Glu 
    530                 535                 540                 


Leu Leu Phe Ser Glu Gly Pro Ser Thr Ser Arg Trp Ala Ala Glu Leu 
545                 550                 555                 560 


Pro Phe Pro Ala Asp Ser Ser Asp Pro Ala Ser Gln Leu Ser Tyr Ser 
                565                 570                 575     


Gln Glu Val Gly Gly Pro Phe Lys Thr Pro Ile Lys Glu Thr Leu Pro 
            580                 585                 590         


Ile Ser Ser Thr Pro Ser Lys Ser Val Leu Pro Arg Thr Pro Glu Ser 
        595                 600                 605             


Trp Arg Leu Thr Pro Pro Ala Lys Val Gly Gly Leu Asp Phe Ser Pro 
    610                 615                 620                 


Val Gln Thr Ser Gln Gly Ala Ser Asp Pro Leu Pro Asp Pro Leu Gly 
625                 630                 635                 640 


Leu Met Asp Leu Ser Thr Thr Pro Leu Gln Ser Ala Pro Pro Leu Glu 
                645                 650                 655     


Ser Pro Gln Arg Leu Leu Ser Ser Glu Pro Leu Asp Leu Ile Ser Val 
            660                 665                 670         


Pro Phe Gly Asn Ser Ser Pro Ser Asp Ile Asp Val Pro Lys Pro Gly 
        675                 680                 685             


Ser Pro Glu Pro Gln Val Ser Gly Leu Ala Ala Asn Arg Ser Leu Thr 
    690                 695                 700                 


Glu Gly Leu Val Leu Asp Thr Met Asn Asp Ser Leu Ser Lys Ile Leu 
705                 710                 715                 720 


Leu Asp Ile Ser Phe Pro Gly Leu Asp Glu Asp Pro Leu Gly Pro Asp 
                725                 730                 735     


Asn Ile Asn Trp Ser Gln Phe Ile Pro Glu Leu Gln 
            740                 745             


<210>  4028
<211>  492
<212>  PRT
<213>  homo sapiens

<400>  4028

Met Lys Ala Thr Thr Pro Leu Gln Thr Val Asp Arg Pro Lys Asp Trp 
1               5                   10                  15      


Tyr Lys Thr Met Phe Lys Gln Ile His Met Val His Lys Pro Asp Asp 
            20                  25                  30          


Asp Thr Asp Met Tyr Asn Thr Pro Tyr Thr Tyr Asn Ala Gly Leu Tyr 
        35                  40                  45              


Asn Pro Pro Tyr Ser Ala Gln Ser His Pro Ala Ala Lys Thr Gln Thr 
    50                  55                  60                  


Tyr Arg Pro Leu Ser Lys Ser His Ser Asp Asn Ser Pro Asn Ala Phe 
65                  70                  75                  80  


Lys Asp Ala Ser Ser Pro Val Pro Pro Pro His Val Pro Pro Pro Val 
                85                  90                  95      


Pro Pro Leu Arg Pro Arg Asp Arg Ser Ser Thr Glu Lys His Asp Trp 
            100                 105                 110         


Asp Pro Pro Asp Arg Lys Val Asp Thr Arg Lys Phe Arg Ser Glu Pro 
        115                 120                 125             


Arg Ser Ile Phe Glu Tyr Glu Pro Gly Lys Ser Ser Ile Leu Gln His 
    130                 135                 140                 


Glu Arg Pro Ala Ser Leu Tyr Gln Ser Ser Ile Asp Arg Ser Leu Glu 
145                 150                 155                 160 


Arg Pro Met Ser Ser Ala Ser Met Ala Ser Asp Phe Arg Lys Arg Arg 
                165                 170                 175     


Lys Ser Glu Pro Ala Val Gly Pro Pro Arg Gly Leu Gly Asp Gln Ser 
            180                 185                 190         


Ala Ser Arg Thr Ser Pro Gly Arg Val Asp Leu Pro Gly Ser Ser Thr 
        195                 200                 205             


Thr Leu Thr Lys Ser Phe Thr Ser Ser Ser Pro Ser Ser Pro Ser Arg 
    210                 215                 220                 


Ala Lys Asp Arg Glu Ser Pro Arg Ser Tyr Ser Ser Thr Leu Thr Asp 
225                 230                 235                 240 


Met Gly Arg Ser Ala Pro Arg Glu Arg Arg Gly Thr Pro Glu Lys Glu 
                245                 250                 255     


Lys Leu Pro Ala Lys Ala Val Tyr Asp Phe Lys Ala Gln Thr Ser Lys 
            260                 265                 270         


Glu Leu Ser Phe Lys Lys Gly Asp Thr Val Tyr Ile Leu Arg Lys Ile 
        275                 280                 285             


Asp Gln Asn Trp Tyr Glu Gly Glu His His Gly Arg Val Gly Ile Phe 
    290                 295                 300                 


Pro Ile Ser Tyr Val Glu Lys Leu Thr Pro Pro Glu Lys Ala Gln Pro 
305                 310                 315                 320 


Ala Arg Pro Pro Pro Pro Ala Gln Pro Gly Glu Ile Gly Glu Ala Ile 
                325                 330                 335     


Ala Lys Tyr Asn Phe Asn Ala Asp Thr Asn Val Glu Leu Ser Leu Arg 
            340                 345                 350         


Lys Gly Asp Arg Val Ile Leu Leu Lys Arg Val Asp Gln Asn Trp Tyr 
        355                 360                 365             


Glu Gly Lys Ile Pro Gly Thr Asn Arg Gln Gly Ile Phe Pro Val Ser 
    370                 375                 380                 


Tyr Val Glu Val Val Lys Lys Asn Thr Lys Gly Ala Glu Asp Tyr Pro 
385                 390                 395                 400 


Asp Pro Pro Ile Pro His Ser Tyr Ser Ser Asp Arg Ile His Ser Leu 
                405                 410                 415     


Ser Ser Asn Lys Pro Gln Arg Pro Val Phe Thr His Glu Asn Ile Gln 
            420                 425                 430         


Gly Gly Gly Glu Pro Phe Gln Ala Leu Tyr Asn Tyr Thr Pro Arg Asn 
        435                 440                 445             


Glu Asp Glu Leu Glu Leu Arg Glu Ser Asp Val Ile Asp Val Met Glu 
    450                 455                 460                 


Lys Cys Asp Asp Gly Trp Phe Val Gly Thr Ser Arg Arg Thr Lys Phe 
465                 470                 475                 480 


Phe Gly Thr Phe Pro Gly Asn Tyr Val Lys Arg Leu 
                485                 490         


<210>  4029
<211>  357
<212>  PRT
<213>  homo sapiens

<400>  4029

Met Ala Arg Glu Asn Gly Glu Ser Ser Ser Ser Trp Lys Lys Gln Ala 
1               5                   10                  15      


Glu Asp Ile Lys Lys Ile Phe Glu Phe Lys Glu Thr Leu Gly Thr Gly 
            20                  25                  30          


Ala Phe Ser Glu Val Val Leu Ala Glu Glu Lys Ala Thr Gly Lys Leu 
        35                  40                  45              


Phe Ala Val Lys Cys Ile Pro Lys Lys Ala Leu Lys Gly Lys Glu Ser 
    50                  55                  60                  


Ser Ile Glu Asn Glu Ile Ala Val Leu Arg Lys Ile Lys His Glu Asn 
65                  70                  75                  80  


Ile Val Ala Leu Glu Asp Ile Tyr Glu Ser Pro Asn His Leu Tyr Leu 
                85                  90                  95      


Val Met Gln Leu Val Ser Gly Gly Glu Leu Phe Asp Arg Ile Val Glu 
            100                 105                 110         


Lys Gly Phe Tyr Thr Glu Lys Asp Ala Ser Thr Leu Ile Arg Gln Val 
        115                 120                 125             


Leu Asp Ala Val Tyr Tyr Leu His Arg Met Gly Ile Val His Arg Asp 
    130                 135                 140                 


Leu Lys Pro Glu Asn Leu Leu Tyr Tyr Ser Gln Asp Glu Glu Ser Lys 
145                 150                 155                 160 


Ile Met Ile Ser Asp Phe Gly Leu Ser Lys Met Glu Gly Lys Gly Asp 
                165                 170                 175     


Val Met Ser Thr Ala Cys Gly Thr Pro Gly Tyr Val Ala Pro Glu Val 
            180                 185                 190         


Leu Ala Gln Lys Pro Tyr Ser Lys Ala Val Asp Cys Trp Ser Ile Gly 
        195                 200                 205             


Val Ile Ala Tyr Ile Leu Leu Cys Gly Tyr Pro Pro Phe Tyr Asp Glu 
    210                 215                 220                 


Asn Asp Ser Lys Leu Phe Glu Gln Ile Leu Lys Ala Glu Tyr Glu Phe 
225                 230                 235                 240 


Asp Ser Pro Tyr Trp Asp Asp Ile Ser Asp Ser Ala Lys Asp Phe Ile 
                245                 250                 255     


Arg Asn Leu Met Glu Lys Asp Pro Asn Lys Arg Tyr Thr Cys Glu Gln 
            260                 265                 270         


Ala Ala Arg His Pro Trp Ile Ala Gly Asp Thr Ala Leu Asn Lys Asn 
        275                 280                 285             


Ile His Glu Ser Val Ser Ala Gln Ile Arg Lys Asn Phe Ala Lys Ser 
    290                 295                 300                 


Lys Trp Arg Gln Ala Phe Asn Ala Thr Ala Val Val Arg His Met Arg 
305                 310                 315                 320 


Lys Leu His Leu Gly Ser Ser Leu Asp Ser Ser Asn Ala Ser Val Ser 
                325                 330                 335     


Ser Ser Leu Ser Leu Ala Ser Gln Lys Asp Cys Ala Tyr Val Ala Lys 
            340                 345                 350         


Pro Glu Ser Leu Ser 
        355         


<210>  4030
<211>  685
<212>  PRT
<213>  homo sapiens

<400>  4030

Met Asn Gln Ser Arg Ser Arg Ser Asp Gly Gly Ser Glu Glu Thr Leu 
1               5                   10                  15      


Pro Gln Asp His Asn His His Glu Asn Glu Arg Arg Trp Gln Gln Glu 
            20                  25                  30          


Arg Leu His Arg Glu Glu Ala Tyr Tyr Gln Phe Ile Asn Glu Leu Asn 
        35                  40                  45              


Asp Glu Asp Tyr Arg Leu Met Arg Asp His Asn Leu Leu Gly Thr Pro 
    50                  55                  60                  


Gly Glu Ile Thr Ser Glu Glu Leu Gln Gln Arg Leu Asp Gly Val Lys 
65                  70                  75                  80  


Glu Gln Leu Ala Ser Gln Pro Asp Leu Arg Asp Gly Thr Asn Tyr Arg 
                85                  90                  95      


Asp Ser Glu Val Pro Arg Glu Ser Ser His Glu Asp Ser Leu Leu Glu 
            100                 105                 110         


Trp Leu Asn Thr Phe Arg Arg Thr Gly Asn Ala Thr Arg Ser Gly Gln 
        115                 120                 125             


Asn Gly Asn Gln Thr Trp Arg Ala Val Ser Arg Thr Asn Pro Asn Asn 
    130                 135                 140                 


Gly Glu Phe Arg Phe Ser Leu Glu Ile His Val Asn His Glu Asn Arg 
145                 150                 155                 160 


Gly Phe Glu Ile His Gly Glu Asp Tyr Thr Asp Ile Pro Leu Ser Asp 
                165                 170                 175     


Ser Asn Arg Asp His Thr Ala Asn Arg Gln Gln Arg Ser Thr Ser Pro 
            180                 185                 190         


Val Ala Arg Arg Thr Arg Ser Gln Thr Ser Val Asn Phe Asn Gly Ser 
        195                 200                 205             


Ser Ser Asn Ile Pro Arg Thr Arg Leu Ala Ser Arg Gly Gln Asn Pro 
    210                 215                 220                 


Ala Glu Gly Ser Phe Ser Thr Leu Gly Arg Leu Arg Asn Gly Ile Gly 
225                 230                 235                 240 


Gly Ala Ala Gly Ile Pro Arg Ala Asn Ala Ser Arg Thr Asn Phe Ser 
                245                 250                 255     


Ser His Thr Asn Gln Ser Gly Gly Ser Glu Leu Arg Gln Arg Glu Gly 
            260                 265                 270         


Gln Arg Phe Gly Ala Ala His Val Trp Glu Asn Gly Ala Arg Ser Asn 
        275                 280                 285             


Val Thr Val Arg Asn Thr Asn Gln Arg Leu Glu Pro Ile Arg Leu Arg 
    290                 295                 300                 


Ser Thr Ser Asn Ser Arg Ser Arg Ser Pro Ile Gln Arg Gln Ser Gly 
305                 310                 315                 320 


Thr Val Tyr His Asn Ser Gln Arg Glu Ser Arg Pro Val Gln Gln Thr 
                325                 330                 335     


Thr Arg Arg Ser Val Arg Arg Arg Gly Arg Thr Arg Val Phe Leu Glu 
            340                 345                 350         


Gln Asp Arg Glu Arg Glu Arg Arg Gly Thr Ala Tyr Thr Pro Phe Ser 
        355                 360                 365             


Asn Ser Arg Leu Val Ser Arg Ile Thr Val Glu Glu Gly Glu Glu Ser 
    370                 375                 380                 


Ser Arg Ser Ser Thr Ala Val Arg Arg His Pro Thr Ile Thr Leu Asp 
385                 390                 395                 400 


Leu Gln Val Arg Arg Ile Arg Pro Gly Glu Asn Arg Asp Arg Asp Ser 
                405                 410                 415     


Ile Ala Asn Arg Thr Arg Ser Arg Val Gly Leu Ala Glu Asn Thr Val 
            420                 425                 430         


Thr Ile Glu Ser Asn Ser Gly Gly Phe Arg Arg Thr Ile Ser Arg Leu 
        435                 440                 445             


Glu Arg Ser Gly Ile Arg Thr Tyr Val Ser Thr Ile Thr Val Pro Leu 
    450                 455                 460                 


Arg Arg Ile Ser Glu Asn Glu Leu Val Glu Pro Ser Ser Val Ala Leu 
465                 470                 475                 480 


Arg Ser Ile Leu Arg Gln Ile Met Thr Gly Phe Gly Glu Leu Ser Ser 
                485                 490                 495     


Leu Met Glu Ala Asp Ser Glu Ser Glu Leu Gln Arg Asn Gly Gln His 
            500                 505                 510         


Leu Pro Asp Met His Ser Glu Leu Ser Asn Leu Gly Thr Asp Asn Asn 
        515                 520                 525             


Arg Ser Gln His Arg Glu Gly Ser Ser Gln Asp Arg Gln Ala Gln Gly 
    530                 535                 540                 


Asp Ser Thr Glu Met His Gly Glu Asn Glu Thr Thr Gln Pro His Thr 
545                 550                 555                 560 


Arg Asn Ser Asp Ser Arg Gly Gly Arg Gln Leu Arg Asn Pro Asn Asn 
                565                 570                 575     


Leu Val Glu Thr Gly Thr Leu Pro Ile Leu Arg Leu Ala His Phe Phe 
            580                 585                 590         


Leu Leu Asn Glu Ser Asp Asp Asp Asp Arg Ile Arg Gly Leu Thr Lys 
        595                 600                 605             


Glu Gln Ile Asp Asn Leu Ser Thr Arg His Tyr Glu His Asn Ser Ile 
    610                 615                 620                 


Asp Ser Glu Leu Gly Lys Ile Cys Ser Val Cys Ile Ser Asp Tyr Val 
625                 630                 635                 640 


Thr Gly Asn Lys Leu Arg Gln Leu Pro Cys Met His Glu Phe His Ile 
                645                 650                 655     


His Cys Ile Asp Arg Trp Leu Ser Glu Asn Cys Thr Cys Pro Ile Cys 
            660                 665                 670         


Arg Gln Pro Val Leu Gly Ser Asn Ile Ala Asn Asn Gly 
        675                 680                 685 


<210>  4031
<211>  255
<212>  PRT
<213>  homo sapiens

<400>  4031

Met Thr Met Thr Thr Met Pro Glu Ser Leu Asn Ser Pro Val Ser Gly 
1               5                   10                  15      


Lys Ala Val Phe Met Glu Phe Gly Pro Pro Asn Gln Gln Met Ser Pro 
            20                  25                  30          


Ser Pro Met Ser His Gly His Tyr Ser Met His Cys Leu His Ser Ala 
        35                  40                  45              


Gly His Ser Gln Pro Asp Gly Ala Tyr Ser Ser Ala Ser Ser Phe Ser 
    50                  55                  60                  


Arg Pro Leu Gly Tyr Pro Tyr Val Asn Ser Val Ser Ser His Ala Ser 
65                  70                  75                  80  


Ser Pro Tyr Ile Ser Ser Val Gln Ser Tyr Pro Gly Ser Ala Ser Leu 
                85                  90                  95      


Ala Gln Ser Arg Leu Glu Asp Pro Gly Ala Asp Ser Glu Lys Ser Thr 
            100                 105                 110         


Val Val Glu Gly Gly Glu Val Arg Phe Asn Gly Lys Gly Lys Lys Ile 
        115                 120                 125             


Arg Lys Pro Arg Thr Ile Tyr Ser Ser Leu Gln Leu Gln Ala Leu Asn 
    130                 135                 140                 


Arg Arg Phe Gln Gln Thr Gln Tyr Leu Ala Leu Pro Glu Arg Ala Glu 
145                 150                 155                 160 


Leu Ala Ala Ser Leu Gly Leu Thr Gln Thr Gln Val Lys Ile Trp Phe 
                165                 170                 175     


Gln Asn Lys Arg Ser Lys Phe Lys Lys Leu Met Lys Gln Gly Gly Ala 
            180                 185                 190         


Ala Leu Glu Gly Ser Ala Leu Ala Asn Gly Arg Ala Leu Ser Ala Gly 
        195                 200                 205             


Ser Pro Pro Val Pro Pro Gly Trp Asn Pro Asn Ser Ser Ser Gly Lys 
    210                 215                 220                 


Gly Ser Gly Gly Asn Ala Gly Ser Tyr Ile Pro Ser Tyr Thr Ser Trp 
225                 230                 235                 240 


Tyr Pro Ser Ala His Gln Glu Ala Met Gln Gln Pro Gln Leu Met 
                245                 250                 255 


<210>  4032
<211>  440
<212>  PRT
<213>  homo sapiens

<400>  4032

Met Ile Ile Pro Ser Leu Glu Glu Leu Asp Ser Leu Lys Tyr Ser Asp 
1               5                   10                  15      


Leu Gln Asn Leu Ala Lys Ser Leu Gly Leu Arg Ala Asn Leu Arg Ala 
            20                  25                  30          


Thr Lys Leu Leu Lys Ala Leu Lys Gly Tyr Ile Lys His Glu Ala Arg 
        35                  40                  45              


Lys Gly Asn Glu Asn Gln Asp Glu Ser Gln Thr Ser Ala Ser Ser Cys 
    50                  55                  60                  


Asp Glu Thr Glu Ile Gln Ile Ser Asn Gln Glu Glu Ala Glu Arg Gln 
65                  70                  75                  80  


Pro Leu Gly His Val Thr Lys Thr Arg Arg Arg Cys Lys Thr Val Arg 
                85                  90                  95      


Val Asp Pro Asp Ser Gln Gln Asn His Ser Glu Ile Lys Ile Ser Asn 
            100                 105                 110         


Pro Thr Glu Phe Gln Asn His Glu Lys Gln Glu Ser Gln Asp Leu Arg 
        115                 120                 125             


Ala Thr Ala Lys Val Pro Ser Pro Pro Asp Glu His Gln Glu Ala Glu 
    130                 135                 140                 


Asn Ala Val Ser Ser Gly Asn Arg Asp Ser Lys Val Pro Ser Glu Gly 
145                 150                 155                 160 


Lys Lys Ser Leu Tyr Thr Asp Glu Ser Ser Lys Pro Gly Lys Asn Lys 
                165                 170                 175     


Arg Thr Ala Ile Thr Thr Pro Asn Phe Lys Lys Leu His Glu Ala His 
            180                 185                 190         


Phe Lys Glu Met Glu Ser Ile Asp Gln Tyr Ile Glu Arg Lys Lys Lys 
        195                 200                 205             


His Phe Glu Glu His Asn Ser Met Asn Glu Leu Lys Gln Pro Ile Asn 
    210                 215                 220                 


Lys Gly Gly Val Arg Thr Pro Val Pro Pro Arg Gly Arg Leu Ser Val 
225                 230                 235                 240 


Ala Ser Thr Pro Ile Ser Gln Arg Arg Ser Gln Gly Arg Ser Cys Gly 
                245                 250                 255     


Pro Ala Ser Gln Ser Thr Leu Gly Leu Lys Gly Ser Leu Lys Arg Ser 
            260                 265                 270         


Ala Ile Ser Ala Ala Lys Thr Gly Val Arg Phe Ser Ala Ala Thr Lys 
        275                 280                 285             


Asp Asn Glu His Lys Arg Ser Leu Thr Lys Thr Pro Ala Arg Lys Ser 
    290                 295                 300                 


Ala His Val Thr Val Ser Gly Gly Thr Pro Lys Gly Glu Ala Val Leu 
305                 310                 315                 320 


Gly Thr His Lys Leu Lys Thr Ile Thr Gly Asn Ser Ala Ala Val Ile 
                325                 330                 335     


Thr Pro Phe Lys Leu Thr Thr Glu Ala Thr Gln Thr Pro Val Ser Asn 
            340                 345                 350         


Lys Lys Pro Val Phe Asp Leu Lys Ala Ser Leu Ser Arg Pro Leu Asn 
        355                 360                 365             


Tyr Glu Pro His Lys Gly Lys Leu Lys Pro Trp Gly Gln Ser Lys Glu 
    370                 375                 380                 


Asn Asn Tyr Leu Asn Gln His Val Asn Arg Ile Asn Phe Tyr Lys Lys 
385                 390                 395                 400 


Thr Tyr Lys Gln Pro His Leu Gln Thr Lys Glu Glu Gln Arg Lys Lys 
                405                 410                 415     


Arg Glu Gln Glu Arg Lys Glu Lys Lys Ala Lys Val Leu Gly Met Arg 
            420                 425                 430         


Arg Gly Leu Ile Leu Ala Glu Asp 
        435                 440 


<210>  4033
<211>  232
<212>  PRT
<213>  homo sapiens

<400>  4033

Met Pro Ser Leu Trp Asp Arg Phe Ser Ser Ser Ser Thr Ser Ser Ser 
1               5                   10                  15      


Pro Ser Ser Leu Pro Arg Thr Pro Thr Pro Asp Arg Pro Pro Arg Ser 
            20                  25                  30          


Ala Trp Gly Ser Ala Thr Arg Glu Glu Gly Phe Asp Arg Ser Thr Ser 
        35                  40                  45              


Leu Glu Ser Ser Asp Cys Glu Ser Leu Asp Ser Ser Asn Ser Gly Phe 
    50                  55                  60                  


Gly Pro Glu Glu Asp Thr Ala Tyr Leu Asp Gly Val Ser Leu Pro Asp 
65                  70                  75                  80  


Phe Glu Leu Leu Ser Asp Pro Glu Asp Glu His Leu Cys Ala Asn Leu 
                85                  90                  95      


Met Gln Leu Leu Gln Glu Ser Leu Ala Gln Ala Arg Leu Gly Ser Arg 
            100                 105                 110         


Arg Pro Ala Arg Leu Leu Met Pro Ser Gln Leu Val Ser Gln Val Gly 
        115                 120                 125             


Lys Glu Leu Leu Arg Leu Ala Tyr Ser Glu Pro Cys Gly Leu Arg Gly 
    130                 135                 140                 


Ala Leu Leu Asp Val Cys Val Glu Gln Gly Lys Ser Cys His Ser Val 
145                 150                 155                 160 


Gly Gln Leu Ala Leu Asp Pro Ser Leu Val Pro Thr Phe Gln Leu Thr 
                165                 170                 175     


Leu Val Leu Arg Leu Asp Ser Arg Leu Trp Pro Lys Ile Gln Gly Leu 
            180                 185                 190         


Phe Ser Ser Ala Asn Ser Pro Phe Leu Pro Gly Phe Ser Gln Ser Leu 
        195                 200                 205             


Thr Leu Ser Thr Gly Phe Arg Val Ile Lys Lys Lys Leu Tyr Ser Ser 
    210                 215                 220                 


Glu Gln Leu Leu Ile Glu Glu Cys 
225                 230         


<210>  4034
<211>  343
<212>  PRT
<213>  homo sapiens

<400>  4034

Met Pro Arg Arg Ser Leu His Ala Ala Ala Val Leu Leu Leu Val Ile 
1               5                   10                  15      


Leu Lys Glu Gln Pro Ser Ser Pro Ala Pro Val Asn Gly Ser Lys Trp 
            20                  25                  30          


Thr Tyr Phe Gly Pro Asp Gly Glu Asn Ser Trp Ser Lys Lys Tyr Pro 
        35                  40                  45              


Ser Cys Gly Gly Leu Leu Gln Ser Pro Ile Asp Leu His Ser Asp Ile 
    50                  55                  60                  


Leu Gln Tyr Asp Ala Ser Leu Thr Pro Leu Glu Phe Gln Gly Tyr Asn 
65                  70                  75                  80  


Leu Ser Ala Asn Lys Gln Phe Leu Leu Thr Asn Asn Gly His Ser Val 
                85                  90                  95      


Lys Leu Asn Leu Pro Ser Asp Met His Ile Gln Gly Leu Gln Ser Arg 
            100                 105                 110         


Tyr Ser Ala Thr Gln Leu His Leu His Trp Gly Asn Pro Asn Asp Pro 
        115                 120                 125             


His Gly Ser Glu His Thr Val Ser Gly Gln His Phe Ala Ala Glu Leu 
    130                 135                 140                 


His Ile Val His Tyr Asn Ser Asp Leu Tyr Pro Asp Ala Ser Thr Ala 
145                 150                 155                 160 


Ser Asn Lys Ser Glu Gly Leu Ala Val Leu Ala Val Leu Ile Glu Met 
                165                 170                 175     


Gly Ser Phe Asn Pro Ser Tyr Asp Lys Ile Phe Ser His Leu Gln His 
            180                 185                 190         


Val Lys Tyr Lys Gly Gln Glu Ala Phe Val Pro Gly Phe Asn Ile Glu 
        195                 200                 205             


Glu Leu Leu Pro Glu Arg Thr Ala Glu Tyr Tyr Arg Tyr Arg Gly Ser 
    210                 215                 220                 


Leu Thr Thr Pro Pro Cys Asn Pro Thr Val Leu Trp Thr Val Phe Arg 
225                 230                 235                 240 


Asn Pro Val Gln Ile Ser Gln Glu Gln Leu Leu Ala Leu Glu Thr Ala 
                245                 250                 255     


Leu Tyr Cys Thr His Met Asp Asp Pro Ser Pro Arg Glu Met Ile Asn 
            260                 265                 270         


Asn Phe Arg Gln Val Gln Lys Phe Asp Glu Arg Leu Val Tyr Thr Ser 
        275                 280                 285             


Phe Ser Gln Gly Ile Ile Leu Ser Leu Ala Leu Ala Gly Ile Leu Gly 
    290                 295                 300                 


Ile Cys Ile Val Val Val Val Ser Ile Trp Leu Phe Arg Arg Lys Ser 
305                 310                 315                 320 


Ile Lys Lys Gly Asp Asn Lys Gly Val Ile Tyr Lys Pro Ala Thr Lys 
                325                 330                 335     


Met Glu Thr Glu Ala His Ala 
            340             


<210>  4035
<211>  503
<212>  PRT
<213>  homo sapiens

<400>  4035

Met Glu Glu His Gly Val Thr Gln Thr Glu His Met Ala Thr Ile Glu 
1               5                   10                  15      


Ala His Ala Val Ala Gln Gln Val Gln Gln Val His Val Ala Thr Tyr 
            20                  25                  30          


Thr Glu His Ser Met Leu Ser Ala Asp Glu Asp Ser Pro Ser Ser Pro 
        35                  40                  45              


Glu Asp Thr Ser Tyr Asp Asp Ser Asp Ile Leu Asn Ser Thr Ala Ala 
    50                  55                  60                  


Asp Glu Val Thr Ala His Leu Ala Ala Ala Gly Pro Val Gly Met Ala 
65                  70                  75                  80  


Ala Ala Ala Ala Val Ala Thr Gly Lys Lys Arg Lys Arg Pro His Val 
                85                  90                  95      


Phe Glu Ser Asn Pro Ser Ile Arg Lys Arg Gln Gln Thr Arg Leu Leu 
            100                 105                 110         


Arg Lys Leu Arg Ala Thr Leu Asp Glu Tyr Thr Thr Arg Val Gly Gln 
        115                 120                 125             


Gln Ala Ile Val Leu Cys Ile Ser Pro Ser Lys Pro Asn Pro Val Phe 
    130                 135                 140                 


Lys Val Phe Gly Ala Ala Pro Leu Glu Asn Val Val Arg Lys Tyr Lys 
145                 150                 155                 160 


Ser Met Ile Leu Glu Asp Leu Glu Ser Ala Leu Ala Glu His Ala Pro 
                165                 170                 175     


Ala Pro Gln Glu Val Asn Ser Glu Leu Pro Pro Leu Thr Ile Asp Gly 
            180                 185                 190         


Ile Pro Val Ser Val Asp Lys Met Thr Gln Ala Gln Leu Arg Ala Phe 
        195                 200                 205             


Ile Pro Glu Met Leu Lys Tyr Ser Thr Gly Arg Gly Lys Pro Gly Trp 
    210                 215                 220                 


Gly Lys Glu Ser Cys Lys Pro Ile Trp Trp Pro Glu Asp Ile Pro Trp 
225                 230                 235                 240 


Ala Asn Val Arg Ser Asp Val Arg Thr Glu Glu Gln Lys Gln Arg Val 
                245                 250                 255     


Ser Trp Thr Gln Ala Leu Arg Thr Ile Val Lys Asn Cys Tyr Lys Gln 
            260                 265                 270         


His Gly Arg Glu Asp Leu Leu Tyr Ala Phe Glu Asp Gln Gln Thr Gln 
        275                 280                 285             


Thr Gln Ala Thr Ala Thr His Ser Ile Ala His Leu Val Pro Ser Gln 
    290                 295                 300                 


Thr Val Val Gln Thr Phe Ser Asn Pro Asp Gly Thr Val Ser Leu Ile 
305                 310                 315                 320 


Gln Val Gly Thr Gly Ala Thr Val Ala Thr Leu Ala Asp Ala Ser Glu 
                325                 330                 335     


Leu Pro Thr Thr Val Thr Val Ala Gln Val Asn Tyr Ser Ala Val Ala 
            340                 345                 350         


Asp Gly Glu Val Glu Gln Asn Trp Ala Thr Leu Gln Gly Gly Glu Met 
        355                 360                 365             


Thr Ile Gln Thr Thr Gln Ala Ser Glu Ala Thr Gln Ala Val Ala Ser 
    370                 375                 380                 


Leu Ala Glu Ala Ala Val Ala Ala Ser Gln Glu Met Gln Gln Gly Ala 
385                 390                 395                 400 


Thr Val Thr Met Ala Leu Asn Ser Glu Ala Ala Ala His Ala Val Ala 
                405                 410                 415     


Thr Leu Ala Glu Ala Thr Leu Gln Gly Gly Gly Gln Ile Val Leu Ser 
            420                 425                 430         


Gly Glu Thr Ala Ala Ala Val Gly Ala Leu Thr Gly Val Gln Asp Ala 
        435                 440                 445             


Asn Gly Leu Val Gln Ile Pro Val Ser Met Tyr Gln Thr Val Val Thr 
    450                 455                 460                 


Ser Leu Ala Gln Gly Asn Gly Pro Val Gln Val Ala Met Ala Pro Val 
465                 470                 475                 480 


Thr Thr Arg Ile Ser Asp Ser Ala Val Thr Met Asp Gly Gln Ala Val 
                485                 490                 495     


Glu Val Val Thr Leu Glu Gln 
            500             


<210>  4036
<211>  661
<212>  PRT
<213>  homo sapiens

<400>  4036

Met Ala Ser Thr Asp Tyr Ser Thr Tyr Ser Gln Ala Ala Ala Gln Gln 
1               5                   10                  15      


Gly Tyr Ser Ala Tyr Thr Ala Gln Pro Thr Gln Gly Tyr Ala Gln Thr 
            20                  25                  30          


Thr Gln Ala Tyr Gly Gln Gln Ser Tyr Gly Thr Tyr Gly Gln Pro Thr 
        35                  40                  45              


Asp Val Ser Tyr Thr Gln Ala Gln Thr Thr Ala Thr Tyr Gly Gln Thr 
    50                  55                  60                  


Ala Tyr Ala Thr Ser Tyr Gly Gln Pro Pro Thr Val Glu Gly Thr Ser 
65                  70                  75                  80  


Thr Gly Tyr Thr Thr Pro Thr Ala Pro Gln Ala Tyr Ser Gln Pro Val 
                85                  90                  95      


Gln Gly Tyr Gly Thr Gly Ala Tyr Asp Thr Thr Thr Ala Thr Val Thr 
            100                 105                 110         


Thr Thr Gln Ala Ser Tyr Ala Ala Gln Ser Ala Tyr Gly Thr Gln Pro 
        115                 120                 125             


Ala Tyr Pro Ala Tyr Gly Gln Gln Pro Ala Ala Thr Ala Pro Thr Arg 
    130                 135                 140                 


Pro Gln Asp Gly Asn Lys Pro Thr Glu Thr Ser Gln Pro Gln Ser Ser 
145                 150                 155                 160 


Thr Gly Gly Tyr Asn Gln Pro Ser Leu Gly Tyr Gly Gln Ser Asn Tyr 
                165                 170                 175     


Ser Tyr Pro Gln Val Pro Gly Ser Tyr Pro Met Gln Pro Val Thr Ala 
            180                 185                 190         


Pro Pro Ser Tyr Pro Pro Thr Ser Tyr Ser Ser Thr Gln Pro Thr Ser 
        195                 200                 205             


Tyr Asp Gln Ser Ser Tyr Ser Gln Gln Asn Thr Tyr Gly Gln Pro Ser 
    210                 215                 220                 


Ser Tyr Gly Gln Gln Ser Ser Tyr Gly Gln Gln Ser Ser Tyr Gly Gln 
225                 230                 235                 240 


Gln Pro Pro Thr Ser Tyr Pro Pro Gln Thr Gly Ser Tyr Ser Gln Ala 
                245                 250                 255     


Pro Ser Gln Tyr Ser Gln Gln Ser Ser Ser Tyr Gly Gln Gln Ser Ser 
            260                 265                 270         


Phe Arg Gln Asp His Pro Ser Ser Met Gly Val Tyr Gly Gln Glu Ser 
        275                 280                 285             


Gly Gly Phe Ser Gly Pro Gly Glu Asn Arg Ser Met Ser Gly Pro Asp 
    290                 295                 300                 


Asn Arg Gly Arg Gly Arg Gly Gly Phe Asp Arg Gly Gly Met Ser Arg 
305                 310                 315                 320 


Gly Gly Arg Gly Gly Gly Arg Gly Gly Met Gly Ala Gly Glu Arg Gly 
                325                 330                 335     


Gly Phe Asn Lys Pro Gly Gly Pro Met Asp Glu Gly Pro Asp Leu Asp 
            340                 345                 350         


Leu Gly Pro Pro Val Asp Pro Asp Glu Asp Ser Asp Asn Ser Ala Ile 
        355                 360                 365             


Tyr Val Gln Gly Leu Asn Asp Ser Val Thr Leu Asp Asp Leu Ala Asp 
    370                 375                 380                 


Phe Phe Lys Gln Cys Gly Val Val Lys Met Asn Lys Arg Thr Gly Gln 
385                 390                 395                 400 


Pro Met Ile His Ile Tyr Leu Asp Lys Glu Thr Gly Lys Pro Lys Gly 
                405                 410                 415     


Asp Ala Thr Val Ser Tyr Glu Asp Pro Pro Thr Ala Lys Ala Ala Val 
            420                 425                 430         


Glu Trp Phe Asp Gly Lys Asp Phe Gln Gly Ser Lys Leu Lys Val Ser 
        435                 440                 445             


Leu Ala Arg Lys Lys Pro Pro Met Asn Ser Met Arg Gly Gly Leu Pro 
    450                 455                 460                 


Pro Arg Glu Gly Arg Gly Met Pro Pro Pro Leu Arg Gly Gly Pro Gly 
465                 470                 475                 480 


Gly Pro Gly Gly Pro Gly Gly Pro Met Gly Arg Met Gly Gly Arg Gly 
                485                 490                 495     


Gly Asp Arg Gly Gly Phe Pro Pro Arg Gly Pro Arg Gly Ser Arg Gly 
            500                 505                 510         


Asn Pro Ser Gly Gly Gly Asn Val Gln His Arg Ala Gly Asp Trp Gln 
        515                 520                 525             


Cys Pro Asn Pro Gly Cys Gly Asn Gln Asn Phe Ala Trp Arg Thr Glu 
    530                 535                 540                 


Cys Asn Gln Cys Lys Ala Pro Lys Pro Glu Gly Phe Leu Pro Pro Pro 
545                 550                 555                 560 


Phe Pro Pro Pro Gly Gly Asp Arg Gly Arg Gly Gly Pro Gly Gly Met 
                565                 570                 575     


Arg Gly Gly Arg Gly Gly Leu Met Asp Arg Gly Gly Pro Gly Gly Met 
            580                 585                 590         


Phe Arg Gly Gly Arg Gly Gly Asp Arg Gly Gly Phe Arg Gly Gly Arg 
        595                 600                 605             


Gly Met Asp Arg Gly Gly Phe Gly Gly Gly Arg Arg Gly Gly Pro Gly 
    610                 615                 620                 


Gly Pro Pro Gly Pro Leu Met Glu Gln Met Gly Gly Arg Arg Gly Gly 
625                 630                 635                 640 


Arg Gly Gly Pro Gly Lys Met Asp Lys Gly Glu His Arg Gln Glu Arg 
                645                 650                 655     


Arg Asp Arg Pro Tyr 
            660     


<210>  4037
<211>  158
<212>  PRT
<213>  homo sapiens

<400>  4037

Met Ser Ser Ala Ile Glu Arg Lys Ser Leu Asp Pro Ser Glu Glu Pro 
1               5                   10                  15      


Val Asp Glu Val Leu Gln Ile Pro Pro Ser Leu Leu Thr Cys Gly Gly 
            20                  25                  30          


Cys Gln Gln Asn Ile Gly Asp Arg Tyr Phe Leu Lys Ala Ile Asp Gln 
        35                  40                  45              


Tyr Trp His Glu Asp Cys Leu Ser Cys Asp Leu Cys Gly Cys Arg Leu 
    50                  55                  60                  


Gly Glu Val Gly Arg Arg Leu Tyr Tyr Lys Leu Gly Arg Lys Leu Cys 
65                  70                  75                  80  


Arg Arg Asp Tyr Leu Arg Leu Phe Gly Gln Asp Gly Leu Cys Ala Ser 
                85                  90                  95      


Cys Asp Lys Arg Ile Arg Ala Tyr Glu Met Thr Met Arg Val Lys Asp 
            100                 105                 110         


Lys Val Tyr His Leu Glu Cys Phe Lys Cys Ala Ala Cys Gln Lys His 
        115                 120                 125             


Phe Cys Val Gly Asp Arg Tyr Leu Leu Ile Asn Ser Asp Ile Val Cys 
    130                 135                 140                 


Glu Gln Asp Ile Tyr Glu Trp Thr Lys Ile Asn Gly Met Ile 
145                 150                 155             


<210>  4038
<211>  1818
<212>  PRT
<213>  homo sapiens

<400>  4038

Met Glu Pro Trp Ser Ser Arg Trp Lys Thr Lys Arg Trp Leu Trp Asp 
1               5                   10                  15      


Phe Thr Val Thr Thr Leu Ala Leu Thr Phe Leu Phe Gln Ala Arg Glu 
            20                  25                  30          


Val Arg Gly Ala Ala Pro Val Asp Val Leu Lys Ala Leu Asp Phe His 
        35                  40                  45              


Asn Ser Pro Glu Gly Ile Ser Lys Thr Thr Gly Phe Cys Thr Asn Arg 
    50                  55                  60                  


Lys Asn Ser Lys Gly Ser Asp Thr Ala Tyr Arg Val Ser Lys Gln Ala 
65                  70                  75                  80  


Gln Leu Ser Ala Pro Thr Lys Gln Leu Phe Pro Gly Gly Thr Phe Pro 
                85                  90                  95      


Glu Asp Phe Ser Ile Leu Phe Thr Val Lys Pro Lys Lys Gly Ile Gln 
            100                 105                 110         


Ser Phe Leu Leu Ser Ile Tyr Asn Glu His Gly Ile Gln Gln Ile Gly 
        115                 120                 125             


Val Glu Val Gly Arg Ser Pro Val Phe Leu Phe Glu Asp His Thr Gly 
    130                 135                 140                 


Lys Pro Ala Pro Glu Asp Tyr Pro Leu Phe Arg Thr Val Asn Ile Ala 
145                 150                 155                 160 


Asp Gly Lys Trp His Arg Val Ala Ile Ser Val Glu Lys Lys Thr Val 
                165                 170                 175     


Thr Met Ile Val Asp Cys Lys Lys Lys Thr Thr Lys Pro Leu Asp Arg 
            180                 185                 190         


Ser Glu Arg Ala Ile Val Asp Thr Asn Gly Ile Thr Val Phe Gly Thr 
        195                 200                 205             


Arg Ile Leu Asp Glu Glu Val Phe Glu Gly Asp Ile Gln Gln Phe Leu 
    210                 215                 220                 


Ile Thr Gly Asp Pro Lys Ala Ala Tyr Asp Tyr Cys Glu His Tyr Ser 
225                 230                 235                 240 


Pro Asp Cys Asp Ser Ser Ala Pro Lys Ala Ala Gln Ala Gln Glu Pro 
                245                 250                 255     


Gln Ile Asp Glu Lys Lys Lys Ser Asn Phe Lys Lys Lys Met Arg Thr 
            260                 265                 270         


Val Ala Thr Lys Ser Lys Glu Lys Ser Lys Lys Phe Thr Pro Pro Lys 
        275                 280                 285             


Ser Glu Lys Phe Ser Ser Lys Lys Lys Lys Ser Tyr Gln Ala Ser Ala 
    290                 295                 300                 


Lys Ala Lys Leu Gly Val Lys Ala Asn Ile Val Asp Asp Phe Gln Glu 
305                 310                 315                 320 


Tyr Asn Tyr Gly Thr Met Glu Ser Tyr Gln Thr Glu Ala Pro Arg His 
                325                 330                 335     


Val Ser Gly Thr Asn Glu Pro Asn Pro Val Glu Glu Ile Phe Thr Glu 
            340                 345                 350         


Glu Tyr Leu Thr Gly Glu Asp Tyr Asp Ser Gln Arg Lys Asn Ser Glu 
        355                 360                 365             


Asp Thr Leu Tyr Glu Asn Lys Glu Ile Asp Gly Arg Asp Ser Asp Leu 
    370                 375                 380                 


Leu Val Asp Gly Asp Leu Gly Glu Tyr Asp Phe Tyr Glu Tyr Lys Glu 
385                 390                 395                 400 


Tyr Glu Asp Lys Pro Thr Ser Pro Pro Asn Glu Glu Phe Gly Pro Gly 
                405                 410                 415     


Val Pro Ala Glu Thr Asp Ile Thr Glu Thr Ser Ile Asn Gly His Gly 
            420                 425                 430         


Ala Tyr Gly Glu Lys Gly Gln Lys Gly Glu Pro Ala Val Val Glu Pro 
        435                 440                 445             


Gly Met Leu Val Glu Gly Pro Pro Gly Pro Ala Gly Pro Ala Gly Ile 
    450                 455                 460                 


Met Gly Pro Pro Gly Leu Gln Gly Pro Thr Gly Pro Pro Gly Asp Pro 
465                 470                 475                 480 


Gly Asp Arg Gly Pro Pro Gly Arg Pro Gly Leu Pro Gly Ala Asp Gly 
                485                 490                 495     


Leu Pro Gly Pro Pro Gly Thr Met Leu Met Leu Pro Phe Arg Tyr Gly 
            500                 505                 510         


Gly Asp Gly Ser Lys Gly Pro Thr Ile Ser Ala Gln Glu Ala Gln Ala 
        515                 520                 525             


Gln Ala Ile Leu Gln Gln Ala Arg Ile Ala Leu Arg Gly Pro Pro Gly 
    530                 535                 540                 


Pro Met Gly Leu Thr Gly Arg Pro Gly Pro Val Gly Gly Pro Gly Ser 
545                 550                 555                 560 


Ser Gly Ala Lys Gly Glu Ser Gly Asp Pro Gly Pro Gln Gly Pro Arg 
                565                 570                 575     


Gly Val Gln Gly Pro Pro Gly Pro Thr Gly Lys Pro Gly Lys Arg Gly 
            580                 585                 590         


Arg Pro Gly Ala Asp Gly Gly Arg Gly Met Pro Gly Glu Pro Gly Ala 
        595                 600                 605             


Lys Gly Asp Arg Gly Phe Asp Gly Leu Pro Gly Leu Pro Gly Asp Lys 
    610                 615                 620                 


Gly His Arg Gly Glu Arg Gly Pro Gln Gly Pro Pro Gly Pro Pro Gly 
625                 630                 635                 640 


Asp Asp Gly Met Arg Gly Glu Asp Gly Glu Ile Gly Pro Arg Gly Leu 
                645                 650                 655     


Pro Gly Glu Ala Gly Pro Arg Gly Leu Leu Gly Pro Arg Gly Thr Pro 
            660                 665                 670         


Gly Ala Pro Gly Gln Pro Gly Met Ala Gly Val Asp Gly Pro Pro Gly 
        675                 680                 685             


Pro Lys Gly Asn Met Gly Pro Gln Gly Glu Pro Gly Pro Pro Gly Gln 
    690                 695                 700                 


Gln Gly Asn Pro Gly Pro Gln Gly Leu Pro Gly Pro Gln Gly Pro Ile 
705                 710                 715                 720 


Gly Pro Pro Gly Glu Lys Gly Pro Gln Gly Lys Pro Gly Leu Ala Gly 
                725                 730                 735     


Leu Pro Gly Ala Asp Gly Pro Pro Gly His Pro Gly Lys Glu Gly Gln 
            740                 745                 750         


Ser Gly Glu Lys Gly Ala Leu Gly Pro Pro Gly Pro Gln Gly Pro Ile 
        755                 760                 765             


Gly Tyr Pro Gly Pro Arg Gly Val Lys Gly Ala Asp Gly Val Arg Gly 
    770                 775                 780                 


Leu Lys Gly Ser Lys Gly Glu Lys Gly Glu Asp Gly Phe Pro Gly Phe 
785                 790                 795                 800 


Lys Gly Asp Met Gly Leu Lys Gly Asp Arg Gly Glu Val Gly Gln Ile 
                805                 810                 815     


Gly Pro Arg Gly Glu Asp Gly Pro Glu Gly Pro Lys Gly Arg Ala Gly 
            820                 825                 830         


Pro Thr Gly Asp Pro Gly Pro Ser Gly Gln Ala Gly Glu Lys Gly Lys 
        835                 840                 845             


Leu Gly Val Pro Gly Leu Pro Gly Tyr Pro Gly Arg Gln Gly Pro Lys 
    850                 855                 860                 


Gly Ser Thr Gly Phe Pro Gly Phe Pro Gly Ala Asn Gly Glu Lys Gly 
865                 870                 875                 880 


Ala Arg Gly Val Ala Gly Lys Pro Gly Pro Arg Gly Gln Arg Gly Pro 
                885                 890                 895     


Thr Gly Pro Arg Gly Ser Arg Gly Ala Arg Gly Pro Thr Gly Lys Pro 
            900                 905                 910         


Gly Pro Lys Gly Thr Ser Gly Gly Asp Gly Pro Pro Gly Pro Pro Gly 
        915                 920                 925             


Glu Arg Gly Pro Gln Gly Pro Gln Gly Pro Val Gly Phe Pro Gly Pro 
    930                 935                 940                 


Lys Gly Pro Pro Gly Pro Pro Gly Lys Asp Gly Leu Pro Gly His Pro 
945                 950                 955                 960 


Gly Gln Arg Gly Glu Thr Gly Phe Gln Gly Lys Thr Gly Pro Pro Gly 
                965                 970                 975     


Pro Gly Gly Val Val Gly Pro Gln Gly Pro Thr Gly Glu Thr Gly Pro 
            980                 985                 990         


Ile Gly Glu Arg Gly His Pro Gly  Pro Pro Gly Pro Pro  Gly Glu Gln 
        995                 1000                 1005             


Gly Leu  Pro Gly Ala Ala Gly  Lys Glu Gly Ala Lys  Gly Asp Pro 
    1010                 1015                 1020             


Gly Pro  Gln Gly Ile Ser Gly  Lys Asp Gly Pro Ala  Gly Leu Arg 
    1025                 1030                 1035             


Gly Phe  Pro Gly Glu Arg Gly  Leu Pro Gly Ala Gln  Gly Ala Pro 
    1040                 1045                 1050             


Gly Leu  Lys Gly Gly Glu Gly  Pro Gln Gly Pro Pro  Gly Pro Val 
    1055                 1060                 1065             


Gly Ser  Pro Gly Glu Arg Gly  Ser Ala Gly Thr Ala  Gly Pro Ile 
    1070                 1075                 1080             


Gly Leu  Pro Gly Arg Pro Gly  Pro Gln Gly Pro Pro  Gly Pro Ala 
    1085                 1090                 1095             


Gly Glu  Lys Gly Ala Pro Gly  Glu Lys Gly Pro Gln  Gly Pro Ala 
    1100                 1105                 1110             


Gly Arg  Asp Gly Val Gln Gly  Pro Val Gly Leu Pro  Gly Pro Ala 
    1115                 1120                 1125             


Gly Pro  Ala Gly Ser Pro Gly  Glu Asp Gly Asp Lys  Gly Glu Ile 
    1130                 1135                 1140             


Gly Glu  Pro Gly Gln Lys Gly  Ser Lys Gly Asp Lys  Gly Glu Asn 
    1145                 1150                 1155             


Gly Pro  Pro Gly Pro Pro Gly  Leu Gln Gly Pro Val  Gly Ala Pro 
    1160                 1165                 1170             


Gly Ile  Ala Gly Gly Asp Gly  Glu Pro Gly Pro Arg  Gly Gln Gln 
    1175                 1180                 1185             


Gly Met  Phe Gly Gln Lys Gly  Asp Glu Gly Ala Arg  Gly Phe Pro 
    1190                 1195                 1200             


Gly Pro  Pro Gly Pro Ile Gly  Leu Gln Gly Leu Pro  Gly Pro Pro 
    1205                 1210                 1215             


Gly Glu  Lys Gly Glu Asn Gly  Asp Val Gly Pro Met  Gly Pro Pro 
    1220                 1225                 1230             


Gly Pro  Pro Gly Pro Arg Gly  Pro Gln Gly Pro Asn  Gly Ala Asp 
    1235                 1240                 1245             


Gly Pro  Gln Gly Pro Pro Gly  Ser Val Gly Ser Val  Gly Gly Val 
    1250                 1255                 1260             


Gly Glu  Lys Gly Glu Pro Gly  Glu Ala Gly Asn Pro  Gly Pro Pro 
    1265                 1270                 1275             


Gly Glu  Ala Gly Val Gly Gly  Pro Lys Gly Glu Arg  Gly Glu Lys 
    1280                 1285                 1290             


Gly Glu  Ala Gly Pro Pro Gly  Ala Ala Gly Pro Pro  Gly Ala Lys 
    1295                 1300                 1305             


Gly Pro  Pro Gly Asp Asp Gly  Pro Lys Gly Asn Pro  Gly Pro Val 
    1310                 1315                 1320             


Gly Phe  Pro Gly Asp Pro Gly  Pro Pro Gly Glu Pro  Gly Pro Ala 
    1325                 1330                 1335             


Gly Gln  Asp Gly Val Gly Gly  Asp Lys Gly Glu Asp  Gly Asp Pro 
    1340                 1345                 1350             


Gly Gln  Pro Gly Pro Pro Gly  Pro Ser Gly Glu Ala  Gly Pro Pro 
    1355                 1360                 1365             


Gly Pro  Pro Gly Lys Arg Gly  Pro Pro Gly Ala Ala  Gly Ala Glu 
    1370                 1375                 1380             


Gly Arg  Gln Gly Glu Lys Gly  Ala Lys Gly Glu Ala  Gly Ala Glu 
    1385                 1390                 1395             


Gly Pro  Pro Gly Lys Thr Gly  Pro Val Gly Pro Gln  Gly Pro Ala 
    1400                 1405                 1410             


Gly Lys  Pro Gly Pro Glu Gly  Leu Arg Gly Ile Pro  Gly Pro Val 
    1415                 1420                 1425             


Gly Glu  Gln Gly Leu Pro Gly  Ala Ala Gly Gln Asp  Gly Pro Pro 
    1430                 1435                 1440             


Gly Pro  Met Gly Pro Pro Gly  Leu Pro Gly Leu Lys  Gly Asp Pro 
    1445                 1450                 1455             


Gly Ser  Lys Gly Glu Lys Gly  His Pro Gly Leu Ile  Gly Leu Ile 
    1460                 1465                 1470             


Gly Pro  Pro Gly Glu Gln Gly  Glu Lys Gly Asp Arg  Gly Leu Pro 
    1475                 1480                 1485             


Gly Thr  Gln Gly Ser Pro Gly  Ala Lys Gly Asp Gly  Gly Ile Pro 
    1490                 1495                 1500             


Gly Pro  Ala Gly Pro Leu Gly  Pro Pro Gly Pro Pro  Gly Leu Pro 
    1505                 1510                 1515             


Gly Pro  Gln Gly Pro Lys Gly  Asn Lys Gly Ser Thr  Gly Pro Ala 
    1520                 1525                 1530             


Gly Gln  Lys Gly Asp Ser Gly  Leu Pro Gly Pro Pro  Gly Ser Pro 
    1535                 1540                 1545             


Gly Pro  Pro Gly Glu Val Ile  Gln Pro Leu Pro Ile  Leu Ser Ser 
    1550                 1555                 1560             


Lys Lys  Thr Arg Arg His Thr  Glu Gly Met Gln Ala  Asp Ala Asp 
    1565                 1570                 1575             


Asp Asn  Ile Leu Asp Tyr Ser  Asp Gly Met Glu Glu  Ile Phe Gly 
    1580                 1585                 1590             


Ser Leu  Asn Ser Leu Lys Gln  Asp Ile Glu His Met  Lys Phe Pro 
    1595                 1600                 1605             


Met Gly  Thr Gln Thr Asn Pro  Ala Arg Thr Cys Lys  Asp Leu Gln 
    1610                 1615                 1620             


Leu Ser  His Pro Asp Phe Pro  Asp Gly Glu Tyr Trp  Ile Asp Pro 
    1625                 1630                 1635             


Asn Gln  Gly Cys Ser Gly Asp  Ser Phe Lys Val Tyr  Cys Asn Phe 
    1640                 1645                 1650             


Thr Ser  Gly Gly Glu Thr Cys  Ile Tyr Pro Asp Lys  Lys Ser Glu 
    1655                 1660                 1665             


Gly Val  Arg Ile Ser Ser Trp  Pro Lys Glu Lys Pro  Gly Ser Trp 
    1670                 1675                 1680             


Phe Ser  Glu Phe Lys Arg Gly  Lys Leu Leu Ser Tyr  Leu Asp Val 
    1685                 1690                 1695             


Glu Gly  Asn Ser Ile Asn Met  Val Gln Met Thr Phe  Leu Lys Leu 
    1700                 1705                 1710             


Leu Thr  Ala Ser Ala Arg Gln  Asn Phe Thr Tyr His  Cys His Gln 
    1715                 1720                 1725             


Ser Ala  Ala Trp Tyr Asp Val  Ser Ser Gly Ser Tyr  Asp Lys Ala 
    1730                 1735                 1740             


Leu Arg  Phe Leu Gly Ser Asn  Asp Glu Glu Met Ser  Tyr Asp Asn 
    1745                 1750                 1755             


Asn Pro  Phe Ile Lys Thr Leu  Tyr Asp Gly Cys Ala  Ser Arg Lys 
    1760                 1765                 1770             


Gly Tyr  Glu Lys Thr Val Ile  Glu Ile Asn Thr Pro  Lys Ile Asp 
    1775                 1780                 1785             


Gln Val  Pro Ile Val Asp Val  Met Ile Asn Asp Phe  Gly Asp Gln 
    1790                 1795                 1800             


Asn Gln  Lys Phe Gly Phe Glu  Val Gly Pro Val Cys  Phe Leu Gly 
    1805                 1810                 1815             


<210>  4039
<211>  557
<212>  PRT
<213>  homo sapiens

<400>  4039

Met Ala Gly Ala Gly Leu Arg Ala Ala Ala Arg Arg Trp Leu Leu Cys 
1               5                   10                  15      


Gly Gly His Gly Gly Pro Arg Ala Ala Ser Ser Ser Pro Ser Cys Pro 
            20                  25                  30          


Gly Cys Gly Pro Pro Gly Pro Gly Ala His Cys Pro Gly Val Pro Arg 
        35                  40                  45              


Ser Ala Pro Ala Gln Ala Pro Thr Ser Gly Ala Asp Leu Ser Ala His 
    50                  55                  60                  


Leu Trp Ala Arg Tyr Gln Asp Met Arg Arg Leu Val His Asp Leu Leu 
65                  70                  75                  80  


Pro Pro Glu Val Cys Ser Leu Leu Asn Pro Ala Ala Ile Tyr Ala Asn 
                85                  90                  95      


Asn Glu Ile Ser Leu Arg Asp Val Glu Val Tyr Gly Phe Asp Tyr Asp 
            100                 105                 110         


Tyr Thr Leu Ala Gln Tyr Ala Asp Ala Leu His Pro Glu Ile Phe Ser 
        115                 120                 125             


Thr Ala Arg Asp Ile Leu Ile Glu His Tyr Lys Tyr Pro Glu Gly Ile 
    130                 135                 140                 


Arg Lys Tyr Asp Tyr Asn Pro Ser Phe Ala Ile Arg Gly Leu His Tyr 
145                 150                 155                 160 


Asp Ile Gln Lys Ser Leu Leu Met Lys Ile Asp Ala Phe His Tyr Val 
                165                 170                 175     


Gln Leu Gly Thr Ala Tyr Arg Gly Leu Gln Pro Val Pro Asp Glu Glu 
            180                 185                 190         


Val Ile Glu Leu Tyr Gly Gly Thr Gln His Ile Pro Leu Tyr Gln Met 
        195                 200                 205             


Ser Gly Phe Tyr Gly Lys Gly Pro Ser Ile Lys Gln Phe Met Asp Ile 
    210                 215                 220                 


Phe Ser Leu Pro Glu Met Ala Leu Leu Ser Cys Val Val Asp Tyr Phe 
225                 230                 235                 240 


Leu Gly His Ser Leu Glu Phe Asp Gln Ala His Leu Tyr Lys Asp Val 
                245                 250                 255     


Thr Asp Ala Ile Arg Asp Val His Val Lys Gly Leu Met Tyr Gln Trp 
            260                 265                 270         


Ile Glu Gln Asp Met Glu Lys Tyr Ile Leu Arg Gly Asp Glu Thr Phe 
        275                 280                 285             


Ala Val Leu Ser Arg Leu Val Ala His Gly Lys Gln Leu Phe Leu Ile 
    290                 295                 300                 


Thr Asn Ser Pro Phe Ser Phe Val Asp Lys Gly Met Arg His Met Val 
305                 310                 315                 320 


Gly Pro Asp Trp Arg Gln Leu Phe Asp Val Val Ile Val Gln Ala Asp 
                325                 330                 335     


Lys Pro Ser Phe Phe Thr Asp Arg Arg Lys Pro Phe Arg Lys Leu Asp 
            340                 345                 350         


Glu Lys Gly Ser Leu Gln Trp Asp Arg Ile Thr Arg Leu Glu Lys Gly 
        355                 360                 365             


Lys Ile Tyr Arg Gln Gly Asn Leu Phe Asp Phe Leu Arg Leu Thr Glu 
    370                 375                 380                 


Trp Arg Gly Pro Arg Val Leu Tyr Phe Gly Asp His Leu Tyr Ser Asp 
385                 390                 395                 400 


Leu Ala Asp Leu Met Leu Arg His Gly Trp Arg Thr Gly Ala Ile Ile 
                405                 410                 415     


Pro Glu Leu Glu Arg Glu Ile Arg Ile Ile Asn Thr Glu Gln Tyr Met 
            420                 425                 430         


His Ser Leu Thr Trp Gln Gln Ala Leu Thr Gly Leu Leu Glu Arg Met 
        435                 440                 445             


Gln Thr Tyr Gln Asp Ala Glu Ser Arg Gln Val Leu Ala Ala Trp Met 
    450                 455                 460                 


Lys Glu Arg Gln Glu Leu Arg Cys Ile Thr Lys Ala Leu Phe Asn Ala 
465                 470                 475                 480 


Gln Phe Gly Ser Ile Phe Arg Thr Phe His Asn Pro Thr Tyr Phe Ser 
                485                 490                 495     


Arg Arg Leu Val Arg Phe Ser Asp Leu Tyr Met Ala Ser Leu Ser Cys 
            500                 505                 510         


Leu Leu Asn Tyr Arg Val Asp Phe Thr Phe Tyr Pro Arg Arg Thr Pro 
        515                 520                 525             


Leu Gln His Glu Ala Pro Leu Trp Met Asp Gln Leu Cys Thr Gly Cys 
    530                 535                 540                 


Met Lys Thr Pro Phe Leu Gly Asp Met Ala His Ile Arg 
545                 550                 555         


<210>  4040
<211>  464
<212>  PRT
<213>  homo sapiens

<400>  4040

Met Glu Thr Leu Ser Phe Pro Arg Tyr Asn Val Ala Glu Ile Val Ile 
1               5                   10                  15      


His Ile Arg Asn Lys Ile Leu Thr Gly Ala Asp Gly Lys Asn Leu Thr 
            20                  25                  30          


Lys Asn Asp Leu Tyr Pro Asn Pro Lys Pro Glu Val Leu His Met Ile 
        35                  40                  45              


Tyr Met Arg Ala Leu Gln Ile Val Tyr Gly Ile Arg Leu Glu His Phe 
    50                  55                  60                  


Tyr Met Met Pro Val Asn Ser Glu Val Met Tyr Pro His Leu Met Glu 
65                  70                  75                  80  


Gly Phe Leu Pro Phe Ser Asn Leu Val Thr His Leu Asp Ser Phe Leu 
                85                  90                  95      


Pro Ile Cys Arg Val Asn Asp Phe Glu Thr Ala Asp Ile Leu Cys Pro 
            100                 105                 110         


Lys Ala Lys Arg Thr Ser Arg Phe Leu Ser Gly Ile Ile Asn Phe Ile 
        115                 120                 125             


His Phe Arg Glu Ala Cys Arg Glu Thr Tyr Met Glu Phe Leu Trp Gln 
    130                 135                 140                 


Tyr Lys Ser Ser Ala Asp Lys Met Gln Gln Leu Asn Ala Ala His Gln 
145                 150                 155                 160 


Glu Ala Leu Met Lys Leu Glu Arg Leu Asp Ser Val Pro Val Glu Glu 
                165                 170                 175     


Gln Glu Glu Phe Lys Gln Leu Ser Asp Gly Ile Gln Glu Leu Gln Gln 
            180                 185                 190         


Ser Leu Asn Gln Asp Phe His Gln Lys Thr Ile Val Leu Gln Glu Gly 
        195                 200                 205             


Asn Ser Gln Lys Lys Ser Asn Ile Ser Glu Lys Thr Lys Arg Leu Asn 
    210                 215                 220                 


Glu Leu Lys Leu Ser Val Val Ser Leu Lys Glu Ile Gln Glu Ser Leu 
225                 230                 235                 240 


Lys Thr Lys Ile Val Asp Ser Pro Glu Lys Leu Lys Asn Tyr Lys Glu 
                245                 250                 255     


Lys Met Lys Asp Thr Val Gln Lys Leu Lys Asn Ala Arg Gln Glu Val 
            260                 265                 270         


Val Glu Lys Tyr Glu Ile Tyr Gly Asp Ser Val Asp Cys Leu Pro Ser 
        275                 280                 285             


Cys Gln Leu Glu Val Gln Leu Tyr Gln Lys Lys Ile Gln Asp Leu Ser 
    290                 295                 300                 


Asp Asn Arg Glu Lys Leu Ala Ser Ile Leu Lys Glu Ser Leu Asn Leu 
305                 310                 315                 320 


Glu Asp Gln Ile Glu Ser Asp Glu Ser Glu Leu Lys Lys Leu Lys Thr 
                325                 330                 335     


Glu Glu Asn Ser Phe Lys Arg Leu Met Ile Val Lys Lys Glu Lys Leu 
            340                 345                 350         


Ala Thr Ala Gln Phe Lys Ile Asn Lys Lys His Glu Asp Val Lys Gln 
        355                 360                 365             


Tyr Lys Arg Thr Val Ile Glu Asp Cys Asn Lys Val Gln Glu Lys Arg 
    370                 375                 380                 


Gly Ala Val Tyr Glu Arg Val Thr Thr Ile Asn Gln Glu Ile Gln Lys 
385                 390                 395                 400 


Ile Lys Leu Gly Ile Gln Gln Leu Lys Asp Ala Ala Glu Arg Glu Lys 
                405                 410                 415     


Leu Lys Ser Gln Glu Ile Phe Leu Asn Leu Lys Thr Ala Leu Glu Lys 
            420                 425                 430         


Tyr His Asp Gly Ile Glu Lys Ala Ala Glu Asp Ser Tyr Ala Lys Ile 
        435                 440                 445             


Asp Glu Lys Thr Ala Glu Leu Lys Arg Lys Met Phe Lys Met Ser Thr 
    450                 455                 460                 


<210>  4041
<211>  464
<212>  PRT
<213>  homo sapiens

<400>  4041

Met Glu Thr Leu Ser Phe Pro Arg Tyr Asn Val Ala Glu Ile Val Ile 
1               5                   10                  15      


His Ile Arg Asn Lys Ile Leu Thr Gly Ala Asp Gly Lys Asn Leu Thr 
            20                  25                  30          


Lys Asn Asp Leu Tyr Pro Asn Pro Lys Pro Glu Val Leu His Met Ile 
        35                  40                  45              


Tyr Met Arg Ala Leu Gln Ile Val Tyr Gly Ile Arg Leu Glu His Phe 
    50                  55                  60                  


Tyr Met Met Pro Val Asn Ser Glu Val Met Tyr Pro His Leu Met Glu 
65                  70                  75                  80  


Gly Phe Leu Pro Phe Ser Asn Leu Val Thr His Leu Asp Ser Phe Leu 
                85                  90                  95      


Pro Ile Cys Arg Val Asn Asp Phe Glu Thr Ala Asp Ile Leu Cys Pro 
            100                 105                 110         


Lys Ala Lys Arg Thr Ser Arg Phe Leu Ser Gly Ile Ile Asn Phe Ile 
        115                 120                 125             


His Phe Arg Glu Ala Cys Arg Glu Thr Tyr Met Glu Phe Leu Trp Gln 
    130                 135                 140                 


Tyr Lys Ser Ser Ala Asp Lys Met Gln Gln Leu Asn Ala Ala His Gln 
145                 150                 155                 160 


Glu Ala Leu Met Lys Leu Glu Arg Leu Asp Ser Val Pro Val Glu Glu 
                165                 170                 175     


Gln Glu Glu Phe Lys Gln Leu Ser Asp Gly Ile Gln Glu Leu Gln Gln 
            180                 185                 190         


Ser Leu Asn Gln Asp Phe His Gln Lys Thr Ile Val Leu Gln Glu Gly 
        195                 200                 205             


Asn Ser Gln Lys Lys Ser Asn Ile Ser Glu Lys Thr Lys Arg Leu Asn 
    210                 215                 220                 


Glu Leu Lys Leu Ser Val Val Ser Leu Lys Glu Ile Gln Glu Ser Leu 
225                 230                 235                 240 


Lys Thr Lys Ile Val Asp Ser Pro Glu Lys Leu Lys Asn Tyr Lys Glu 
                245                 250                 255     


Lys Met Lys Asp Thr Val Gln Lys Leu Lys Asn Ala Arg Gln Glu Val 
            260                 265                 270         


Val Glu Lys Tyr Glu Ile Tyr Gly Asp Ser Val Asp Cys Leu Pro Ser 
        275                 280                 285             


Cys Gln Leu Glu Val Gln Leu Tyr Gln Lys Lys Ile Gln Asp Leu Ser 
    290                 295                 300                 


Asp Asn Arg Glu Lys Leu Ala Ser Ile Leu Lys Glu Ser Leu Asn Leu 
305                 310                 315                 320 


Glu Asp Gln Ile Glu Ser Asp Glu Ser Glu Leu Lys Lys Leu Lys Thr 
                325                 330                 335     


Glu Glu Asn Ser Phe Lys Arg Leu Met Ile Val Lys Lys Glu Lys Leu 
            340                 345                 350         


Ala Thr Ala Gln Phe Lys Ile Asn Lys Lys His Glu Asp Val Lys Gln 
        355                 360                 365             


Tyr Lys Arg Thr Val Ile Glu Asp Cys Asn Lys Val Gln Glu Lys Arg 
    370                 375                 380                 


Gly Ala Val Tyr Glu Arg Val Thr Thr Ile Asn Gln Glu Ile Gln Lys 
385                 390                 395                 400 


Ile Lys Leu Gly Ile Gln Gln Leu Lys Asp Ala Ala Glu Arg Glu Lys 
                405                 410                 415     


Leu Lys Ser Gln Glu Ile Phe Leu Asn Leu Lys Thr Ala Leu Glu Lys 
            420                 425                 430         


Tyr His Asp Gly Ile Glu Lys Ala Ala Glu Asp Ser Tyr Ala Lys Ile 
        435                 440                 445             


Asp Glu Lys Thr Ala Glu Leu Lys Arg Lys Met Phe Lys Met Ser Thr 
    450                 455                 460                 


<210>  4042
<211>  326
<212>  PRT
<213>  homo sapiens

<400>  4042

Met Lys Gln Asp Ala Ser Arg Asn Ala Ala Tyr Thr Val Asp Cys Glu 
1               5                   10                  15      


Asp Tyr Val His Val Val Glu Phe Asn Pro Phe Glu Asn Gly Asp Ser 
            20                  25                  30          


Gly Asn Leu Ile Ala Tyr Gly Gly Asn Asn Tyr Val Val Ile Gly Thr 
        35                  40                  45              


Cys Thr Phe Gln Glu Glu Glu Ala Asp Val Glu Gly Ile Gln Tyr Lys 
    50                  55                  60                  


Thr Leu Arg Thr Phe His His Gly Val Arg Val Asp Gly Ile Ala Trp 
65                  70                  75                  80  


Ser Pro Glu Thr Arg Leu Asp Ser Leu Pro Pro Val Ile Lys Phe Cys 
                85                  90                  95      


Thr Ser Ala Ala Asp Met Lys Ile Arg Leu Phe Thr Ser Asp Leu Gln 
            100                 105                 110         


Asp Lys Asn Glu Tyr Lys Val Leu Glu Gly His Thr Asp Phe Ile Asn 
        115                 120                 125             


Gly Leu Val Phe Asp Pro Lys Glu Gly Gln Glu Ile Ala Ser Val Ser 
    130                 135                 140                 


Asp Asp His Thr Cys Arg Ile Trp Asn Leu Glu Gly Val Gln Thr Ala 
145                 150                 155                 160 


His Phe Val Leu His Ser Pro Gly Met Ser Val Cys Trp His Pro Glu 
                165                 170                 175     


Glu Thr Phe Lys Leu Met Val Ala Glu Lys Asn Gly Thr Ile Arg Phe 
            180                 185                 190         


Tyr Asp Leu Leu Ala Gln Gln Ala Ile Leu Ser Leu Glu Ser Glu Gln 
        195                 200                 205             


Val Pro Leu Met Ser Ala His Trp Cys Leu Lys Asn Thr Phe Lys Val 
    210                 215                 220                 


Gly Ala Val Ala Gly Asn Asp Trp Leu Ile Trp Asp Ile Thr Arg Ser 
225                 230                 235                 240 


Ser Tyr Pro Gln Asn Lys Arg Pro Val His Met Asp Arg Ala Cys Leu 
                245                 250                 255     


Phe Arg Trp Ser Thr Ile Ser Glu Asn Leu Phe Ala Thr Thr Gly Tyr 
            260                 265                 270         


Pro Gly Lys Met Ala Ser Gln Phe Gln Ile His His Leu Gly His Pro 
        275                 280                 285             


Gln Pro Ile Leu Met Gly Ser Val Ala Val Gly Ser Gly Leu Ser Trp 
    290                 295                 300                 


His Arg Thr Leu Pro Leu Cys Val Ile Gly Gly Asp His Lys Leu Leu 
305                 310                 315                 320 


Phe Trp Val Thr Glu Val 
                325     


<210>  4043
<211>  599
<212>  PRT
<213>  homo sapiens

<400>  4043

Met Ser Thr Gly Phe Ser Phe Gly Ser Gly Thr Leu Gly Ser Thr Thr 
1               5                   10                  15      


Val Ala Ala Gly Gly Thr Ser Thr Gly Gly Val Phe Ser Phe Gly Thr 
            20                  25                  30          


Gly Ala Ser Ser Asn Pro Ser Val Gly Leu Asn Phe Gly Asn Leu Gly 
        35                  40                  45              


Ser Thr Ser Thr Pro Ala Thr Thr Ser Ala Pro Ser Ser Gly Phe Gly 
    50                  55                  60                  


Thr Gly Leu Phe Gly Ser Lys Pro Ala Thr Gly Phe Thr Leu Gly Gly 
65                  70                  75                  80  


Thr Asn Thr Gly Ile Ala Thr Thr Ile Thr Thr Gly Leu Thr Leu Gly 
                85                  90                  95      


Thr Pro Ala Thr Thr Ser Ala Ala Thr Thr Gly Phe Ser Leu Gly Phe 
            100                 105                 110         


Asn Lys Pro Ala Ala Ser Ala Thr Pro Phe Ala Leu Pro Ile Thr Ser 
        115                 120                 125             


Thr Ser Ala Ser Gly Leu Thr Leu Ser Ser Ala Leu Thr Ser Thr Pro 
    130                 135                 140                 


Ala Ala Ser Thr Gly Phe Thr Leu Asn Asn Leu Gly Gly Thr Thr Ala 
145                 150                 155                 160 


Thr Thr Thr Thr Ala Ser Thr Gly Leu Ser Leu Gly Gly Ala Leu Ala 
                165                 170                 175     


Gly Leu Gly Gly Ser Leu Phe Gln Ser Thr Asn Thr Gly Thr Ser Gly 
            180                 185                 190         


Leu Gly Gln Asn Ala Leu Gly Leu Thr Leu Gly Thr Thr Ala Ala Thr 
        195                 200                 205             


Ser Thr Ala Gly Asn Glu Gly Leu Gly Gly Ile Asp Phe Ser Ser Ser 
    210                 215                 220                 


Ser Asp Lys Lys Ser Asp Lys Thr Gly Thr Arg Pro Glu Asp Ser Lys 
225                 230                 235                 240 


Ala Leu Lys Asp Glu Asn Leu Pro Pro Val Ile Cys Gln Asp Val Glu 
                245                 250                 255     


Asn Leu Gln Lys Phe Val Lys Glu Gln Lys Gln Val Gln Glu Glu Ile 
            260                 265                 270         


Ser Arg Met Ser Ser Lys Ala Met Leu Lys Val Gln Glu Asp Ile Lys 
        275                 280                 285             


Ala Leu Lys Gln Leu Leu Ser Leu Ala Ala Asn Gly Ile Gln Arg Asn 
    290                 295                 300                 


Thr Leu Asn Ile Asp Lys Leu Lys Ile Glu Thr Ala Gln Glu Leu Lys 
305                 310                 315                 320 


Asn Ala Glu Ile Ala Leu Arg Thr Gln Lys Thr Pro Pro Gly Leu Gln 
                325                 330                 335     


His Glu Tyr Ala Ala Pro Ala Asp Tyr Phe Arg Ile Leu Val Gln Gln 
            340                 345                 350         


Phe Glu Val Gln Leu Gln Gln Tyr Arg Gln Gln Ile Glu Glu Leu Glu 
        355                 360                 365             


Asn His Leu Ala Thr Gln Ala Asn Asn Ser His Ile Thr Pro Gln Asp 
    370                 375                 380                 


Leu Ser Met Ala Met Gln Lys Ile Tyr Gln Thr Phe Val Ala Leu Ala 
385                 390                 395                 400 


Ala Gln Leu Gln Ser Ile His Glu Asn Val Lys Val Leu Lys Glu Gln 
                405                 410                 415     


Tyr Leu Gly Tyr Arg Lys Met Phe Leu Gly Asp Ala Val Asp Val Phe 
            420                 425                 430         


Glu Thr Arg Arg Ala Glu Ala Lys Lys Trp Gln Asn Thr Pro Arg Val 
        435                 440                 445             


Thr Thr Gly Pro Thr Pro Phe Ser Thr Met Pro Asn Ala Ala Ala Val 
    450                 455                 460                 


Ala Met Ala Ala Thr Leu Thr Gln Gln Gln Gln Pro Ala Thr Gly Pro 
465                 470                 475                 480 


Gln Pro Ser Leu Gly Val Ser Phe Gly Thr Pro Phe Gly Ser Gly Ile 
                485                 490                 495     


Gly Thr Gly Leu Gln Ser Ser Gly Leu Gly Ser Ser Asn Leu Gly Gly 
            500                 505                 510         


Phe Gly Thr Ser Ser Gly Phe Gly Cys Ser Thr Thr Gly Ala Ser Thr 
        515                 520                 525             


Phe Gly Phe Gly Thr Thr Asn Lys Pro Ser Gly Ser Leu Ser Ala Gly 
    530                 535                 540                 


Phe Gly Ser Ser Ser Thr Ser Gly Phe Asn Phe Ser Asn Pro Gly Ile 
545                 550                 555                 560 


Thr Ala Ser Ala Gly Leu Thr Phe Gly Val Ser Asn Pro Ala Ser Ala 
                565                 570                 575     


Gly Phe Gly Thr Gly Gly Gln Leu Leu Gln Leu Lys Lys Pro Pro Ala 
            580                 585                 590         


Gly Asn Lys Arg Gly Lys Arg 
        595                 


<210>  4044
<211>  587
<212>  PRT
<213>  homo sapiens

<400>  4044

Met Ser Thr Gly Phe Ser Phe Gly Ser Gly Thr Leu Gly Ser Thr Thr 
1               5                   10                  15      


Val Ala Ala Gly Gly Thr Ser Thr Gly Gly Val Phe Ser Phe Gly Thr 
            20                  25                  30          


Gly Ala Ser Ser Asn Pro Ser Val Gly Leu Asn Phe Gly Asn Leu Gly 
        35                  40                  45              


Ser Thr Ser Thr Pro Ala Thr Thr Ser Ala Pro Ser Ser Gly Phe Gly 
    50                  55                  60                  


Thr Gly Leu Phe Gly Ser Lys Pro Ala Thr Gly Phe Thr Leu Gly Gly 
65                  70                  75                  80  


Thr Asn Thr Gly Thr Pro Ala Thr Thr Ser Ala Ala Thr Thr Gly Phe 
                85                  90                  95      


Ser Leu Gly Phe Asn Lys Pro Ala Ala Ser Ala Thr Pro Phe Ala Leu 
            100                 105                 110         


Pro Ile Thr Ser Thr Ser Ala Ser Gly Leu Thr Leu Ser Ser Ala Leu 
        115                 120                 125             


Thr Ser Thr Pro Ala Ala Ser Thr Gly Phe Thr Leu Asn Asn Leu Gly 
    130                 135                 140                 


Gly Thr Thr Ala Thr Thr Thr Thr Ala Ser Thr Gly Leu Ser Leu Gly 
145                 150                 155                 160 


Gly Ala Leu Ala Gly Leu Gly Gly Ser Leu Phe Gln Ser Thr Asn Thr 
                165                 170                 175     


Gly Thr Ser Gly Leu Gly Gln Asn Ala Leu Gly Leu Thr Leu Gly Thr 
            180                 185                 190         


Thr Ala Ala Thr Ser Thr Ala Gly Asn Glu Gly Leu Gly Gly Ile Asp 
        195                 200                 205             


Phe Ser Ser Ser Ser Asp Lys Lys Ser Asp Lys Thr Gly Thr Arg Pro 
    210                 215                 220                 


Glu Asp Ser Lys Ala Leu Lys Asp Glu Asn Leu Pro Pro Val Ile Cys 
225                 230                 235                 240 


Gln Asp Val Glu Asn Leu Gln Lys Phe Val Lys Glu Gln Lys Gln Val 
                245                 250                 255     


Gln Glu Glu Ile Ser Arg Met Ser Ser Lys Ala Met Leu Lys Val Gln 
            260                 265                 270         


Glu Asp Ile Lys Ala Leu Lys Gln Leu Leu Ser Leu Ala Ala Asn Gly 
        275                 280                 285             


Ile Gln Arg Asn Thr Leu Asn Ile Asp Lys Leu Lys Ile Glu Thr Ala 
    290                 295                 300                 


Gln Glu Leu Lys Asn Ala Glu Ile Ala Leu Arg Thr Gln Lys Thr Pro 
305                 310                 315                 320 


Pro Gly Leu Gln His Glu Tyr Ala Ala Pro Ala Asp Tyr Phe Arg Ile 
                325                 330                 335     


Leu Val Gln Gln Phe Glu Val Gln Leu Gln Gln Tyr Arg Gln Gln Ile 
            340                 345                 350         


Glu Glu Leu Glu Asn His Leu Ala Thr Gln Ala Asn Asn Ser His Ile 
        355                 360                 365             


Thr Pro Gln Asp Leu Ser Met Ala Met Gln Lys Ile Tyr Gln Thr Phe 
    370                 375                 380                 


Val Ala Leu Ala Ala Gln Leu Gln Ser Ile His Glu Asn Val Lys Val 
385                 390                 395                 400 


Leu Lys Glu Gln Tyr Leu Gly Tyr Arg Lys Met Phe Leu Gly Asp Ala 
                405                 410                 415     


Val Asp Val Phe Glu Thr Arg Arg Ala Glu Ala Lys Lys Trp Gln Asn 
            420                 425                 430         


Thr Pro Arg Val Thr Thr Gly Pro Thr Pro Phe Ser Thr Met Pro Asn 
        435                 440                 445             


Ala Ala Ala Val Ala Met Ala Ala Thr Leu Thr Gln Gln Gln Gln Pro 
    450                 455                 460                 


Ala Thr Gly Pro Gln Pro Ser Leu Gly Val Ser Phe Gly Thr Pro Phe 
465                 470                 475                 480 


Gly Ser Gly Ile Gly Thr Gly Leu Gln Ser Ser Gly Leu Gly Ser Ser 
                485                 490                 495     


Asn Leu Gly Gly Phe Gly Thr Ser Ser Gly Phe Gly Cys Ser Thr Thr 
            500                 505                 510         


Gly Ala Ser Thr Phe Gly Phe Gly Thr Thr Asn Lys Pro Ser Gly Ser 
        515                 520                 525             


Leu Ser Ala Gly Phe Gly Ser Ser Ser Thr Ser Gly Phe Asn Phe Ser 
    530                 535                 540                 


Asn Pro Gly Ile Thr Ala Ser Ala Gly Leu Thr Phe Gly Val Ser Asn 
545                 550                 555                 560 


Pro Ala Ser Ala Gly Phe Gly Thr Gly Gly Gln Leu Leu Gln Leu Lys 
                565                 570                 575     


Lys Pro Pro Ala Gly Asn Lys Arg Gly Lys Arg 
            580                 585         


<210>  4045
<211>  552
<212>  PRT
<213>  homo sapiens

<400>  4045

Met Ser Pro Leu Trp Trp Gly Phe Leu Leu Ser Cys Leu Gly Cys Lys 
1               5                   10                  15      


Ile Leu Pro Gly Ala Gln Gly Gln Phe Pro Arg Val Cys Met Thr Val 
            20                  25                  30          


Asp Ser Leu Val Asn Lys Glu Cys Cys Pro Arg Leu Gly Ala Glu Ser 
        35                  40                  45              


Ala Asn Val Cys Gly Ser Gln Gln Gly Arg Gly Gln Cys Thr Glu Val 
    50                  55                  60                  


Arg Ala Asp Thr Arg Pro Trp Ser Gly Pro Tyr Ile Leu Arg Asn Gln 
65                  70                  75                  80  


Asp Asp Arg Glu Leu Trp Pro Arg Lys Phe Phe His Arg Thr Cys Lys 
                85                  90                  95      


Cys Thr Gly Asn Phe Ala Gly Tyr Asn Cys Gly Asp Cys Lys Phe Gly 
            100                 105                 110         


Trp Thr Gly Pro Asn Cys Glu Arg Lys Lys Pro Pro Val Ile Arg Gln 
        115                 120                 125             


Asn Ile His Ser Leu Ser Pro Gln Glu Arg Glu Gln Phe Leu Gly Ala 
    130                 135                 140                 


Leu Asp Leu Ala Lys Lys Arg Val His Pro Asp Tyr Val Ile Thr Thr 
145                 150                 155                 160 


Gln His Trp Leu Gly Leu Leu Gly Pro Asn Gly Thr Gln Pro Gln Phe 
                165                 170                 175     


Ala Asn Cys Ser Val Tyr Asp Phe Phe Val Trp Leu His Tyr Tyr Ser 
            180                 185                 190         


Val Arg Asp Thr Leu Leu Gly Pro Gly Arg Pro Tyr Arg Ala Ile Asp 
        195                 200                 205             


Phe Ser His Gln Gly Pro Ala Phe Val Thr Trp His Arg Tyr His Leu 
    210                 215                 220                 


Leu Cys Leu Glu Arg Asp Leu Gln Arg Leu Ile Gly Asn Glu Ser Phe 
225                 230                 235                 240 


Ala Leu Pro Tyr Trp Asn Phe Ala Thr Gly Arg Asn Glu Cys Asp Val 
                245                 250                 255     


Cys Thr Asp Gln Leu Phe Gly Ala Ala Arg Pro Asp Asp Pro Thr Leu 
            260                 265                 270         


Ile Ser Arg Asn Ser Arg Phe Ser Ser Trp Glu Thr Val Cys Asp Ser 
        275                 280                 285             


Leu Asp Asp Tyr Asn His Leu Val Thr Leu Cys Asn Gly Thr Tyr Glu 
    290                 295                 300                 


Gly Leu Leu Arg Arg Asn Gln Met Gly Arg Asn Ser Met Lys Leu Pro 
305                 310                 315                 320 


Thr Leu Lys Asp Ile Arg Asp Cys Leu Ser Leu Gln Lys Phe Asp Asn 
                325                 330                 335     


Pro Pro Phe Phe Gln Asn Ser Thr Phe Ser Phe Arg Asn Ala Leu Glu 
            340                 345                 350         


Gly Phe Asp Lys Ala Asp Gly Thr Leu Asp Ser Gln Val Met Ser Leu 
        355                 360                 365             


His Asn Leu Val His Ser Phe Leu Asn Gly Thr Asn Ala Leu Pro His 
    370                 375                 380                 


Ser Ala Ala Asn Asp Pro Ile Phe Val Val Ile Ser Asn Arg Leu Leu 
385                 390                 395                 400 


Tyr Asn Ala Thr Thr Asn Ile Leu Glu His Val Arg Lys Glu Lys Ala 
                405                 410                 415     


Thr Lys Glu Leu Pro Ser Leu His Val Leu Val Leu His Ser Phe Thr 
            420                 425                 430         


Asp Ala Ile Phe Asp Glu Trp Met Lys Arg Phe Asn Pro Pro Ala Asp 
        435                 440                 445             


Ala Trp Pro Gln Glu Leu Ala Pro Ile Gly His Asn Arg Met Tyr Asn 
    450                 455                 460                 


Met Val Pro Phe Phe Pro Pro Val Thr Asn Glu Glu Leu Phe Leu Thr 
465                 470                 475                 480 


Ser Asp Gln Leu Gly Tyr Ser Tyr Ala Ile Asp Leu Pro Val Ser Val 
                485                 490                 495     


Glu Glu Thr Pro Gly Trp Pro Thr Thr Leu Leu Val Val Met Gly Thr 
            500                 505                 510         


Leu Val Ala Leu Val Gly Leu Phe Val Leu Leu Ala Phe Leu Gln Tyr 
        515                 520                 525             


Arg Arg Leu Arg Lys Gly Tyr Thr Pro Leu Met Glu Thr His Leu Ser 
    530                 535                 540                 


Ser Lys Arg Tyr Thr Glu Glu Ala 
545                 550         


<210>  4046
<211>  233
<212>  PRT
<213>  homo sapiens

<400>  4046

Met Ala Leu Pro Gly Ser Ser Gln Asp Gln Ala Trp Ser Leu Glu Pro 
1               5                   10                  15      


Pro Ala Ala Thr Ala Ala Ala Ser Ser Ser Ser Gly Pro Gln Glu Arg 
            20                  25                  30          


Glu Gly Ala Gly Ser Pro Ala Ala Pro Gly Thr Leu Pro Leu Glu Lys 
        35                  40                  45              


Val Lys Arg Pro Met Asn Ala Phe Met Val Trp Ser Ser Ala Gln Arg 
    50                  55                  60                  


Arg Gln Met Ala Gln Gln Asn Pro Lys Met His Asn Ser Glu Ile Ser 
65                  70                  75                  80  


Lys Arg Leu Gly Ala Gln Trp Lys Leu Leu Asp Glu Asp Glu Lys Arg 
                85                  90                  95      


Pro Phe Val Glu Glu Ala Lys Arg Leu Arg Ala Arg His Leu Arg Asp 
            100                 105                 110         


Tyr Pro Asp Tyr Lys Tyr Arg Pro Arg Arg Lys Ala Lys Ser Ser Gly 
        115                 120                 125             


Ala Gly Pro Ser Arg Cys Gly Gln Gly Arg Gly Asn Leu Ala Ser Gly 
    130                 135                 140                 


Gly Pro Leu Trp Gly Pro Gly Tyr Ala Thr Thr Gln Pro Ser Arg Gly 
145                 150                 155                 160 


Phe Gly Tyr Arg Pro Pro Ser Tyr Ser Thr Ala Tyr Leu Pro Gly Ser 
                165                 170                 175     


Tyr Gly Ser Ser His Cys Lys Leu Glu Ala Pro Ser Pro Cys Ser Leu 
            180                 185                 190         


Pro Gln Ser Asp Pro Arg Leu Gln Gly Glu Leu Leu Pro Thr Tyr Thr 
        195                 200                 205             


His Tyr Leu Pro Pro Gly Ser Pro Thr Pro Tyr Asn Pro Pro Leu Ala 
    210                 215                 220                 


Gly Ala Pro Met Pro Leu Thr His Leu 
225                 230             


<210>  4047
<211>  115
<212>  PRT
<213>  homo sapiens

<400>  4047

Met Ala Val Ala Val Leu Leu Cys Gly Cys Ile Val Ala Thr Val Ser 
1               5                   10                  15      


Phe Phe Trp Glu Glu Ser Leu Thr Gln His Val Ala Gly Leu Leu Phe 
            20                  25                  30          


Leu Met Thr Gly Ile Phe Cys Thr Ile Ser Leu Cys Thr Tyr Ala Ala 
        35                  40                  45              


Ser Ile Ser Tyr Asp Leu Asn Arg Leu Pro Lys Leu Ile Tyr Ser Leu 
    50                  55                  60                  


Pro Ala Asp Val Glu His Gly Tyr Ser Trp Ser Ile Phe Cys Ala Trp 
65                  70                  75                  80  


Cys Ser Leu Gly Phe Ile Val Ala Ala Gly Gly Leu Cys Ile Ala Tyr 
                85                  90                  95      


Pro Phe Ile Ser Arg Thr Lys Ile Ala Gln Leu Lys Ser Gly Arg Asp 
            100                 105                 110         


Ser Thr Val 
        115 


<210>  4048
<211>  297
<212>  PRT
<213>  homo sapiens

<400>  4048

Met Glu Pro Arg Ala Leu Val Thr Ala Leu Ser Leu Gly Leu Ser Leu 
1               5                   10                  15      


Cys Ser Leu Gly Leu Leu Val Thr Ala Ile Phe Thr Asp His Trp Tyr 
            20                  25                  30          


Glu Thr Asp Pro Arg Arg His Lys Glu Ser Cys Glu Arg Ser Arg Ala 
        35                  40                  45              


Gly Ala Asp Pro Pro Asp Gln Lys Asn Arg Leu Met Pro Leu Ser His 
    50                  55                  60                  


Leu Pro Leu Arg Asp Ser Pro Pro Leu Gly Arg Arg Leu Leu Pro Gly 
65                  70                  75                  80  


Gly Pro Gly Arg Ala Asp Pro Glu Ser Trp Arg Ser Leu Leu Gly Leu 
                85                  90                  95      


Gly Gly Leu Asp Ala Glu Cys Gly Arg Pro Leu Phe Ala Thr Tyr Ser 
            100                 105                 110         


Gly Leu Trp Arg Lys Cys Tyr Phe Leu Gly Ile Asp Arg Asp Ile Asp 
        115                 120                 125             


Thr Leu Ile Leu Lys Gly Ile Ala Gln Arg Cys Thr Ala Ile Lys Tyr 
    130                 135                 140                 


His Phe Ser Gln Pro Ile Arg Leu Arg Asn Ile Pro Phe Asn Leu Thr 
145                 150                 155                 160 


Lys Thr Ile Gln Gln Asp Glu Trp His Leu Leu His Leu Arg Arg Ile 
                165                 170                 175     


Thr Ala Gly Phe Leu Gly Met Ala Val Ala Val Leu Leu Cys Gly Cys 
            180                 185                 190         


Ile Val Ala Thr Val Ser Phe Phe Trp Glu Glu Ser Leu Thr Gln His 
        195                 200                 205             


Val Ala Gly Leu Leu Phe Leu Met Thr Gly Ile Phe Cys Thr Ile Ser 
    210                 215                 220                 


Leu Cys Thr Tyr Ala Ala Ser Ile Ser Tyr Asp Leu Asn Arg Leu Pro 
225                 230                 235                 240 


Lys Leu Ile Tyr Ser Leu Pro Ala Asp Val Glu His Gly Tyr Ser Trp 
                245                 250                 255     


Ser Ile Phe Cys Ala Trp Cys Ser Leu Gly Phe Ile Val Ala Ala Gly 
            260                 265                 270         


Gly Leu Cys Ile Ala Tyr Pro Phe Ile Ser Arg Thr Lys Ile Ala Gln 
        275                 280                 285             


Leu Lys Ser Gly Arg Asp Ser Thr Val 
    290                 295         


<210>  4049
<211>  1383
<212>  PRT
<213>  homo sapiens

<400>  4049

Met Tyr Ala Thr Asp Ser Arg Gly His Ser Pro Ala Phe Leu Gln Pro 
1               5                   10                  15      


Gln Asn Gly Asn Ser Arg His Pro Ser Gly Tyr Val Pro Gly Lys Val 
            20                  25                  30          


Val Pro Leu Arg Pro Pro Pro Pro Pro Lys Ser Gln Ala Ser Ala Lys 
        35                  40                  45              


Phe Thr Ser Ile Arg Arg Glu Asp Arg Ala Thr Phe Ala Phe Ser Pro 
    50                  55                  60                  


Glu Glu Gln Gln Ala Gln Arg Glu Ser Gln Lys Gln Lys Arg His Lys 
65                  70                  75                  80  


Asn Thr Phe Ile Cys Phe Ala Ile Thr Ser Phe Ser Phe Phe Ile Ala 
                85                  90                  95      


Leu Ala Ile Ile Leu Gly Ile Ser Ser Lys Tyr Ala Pro Asp Glu Asn 
            100                 105                 110         


Cys Pro Asp Gln Asn Pro Arg Leu Arg Asn Trp Asp Pro Gly Gln Asp 
        115                 120                 125             


Ser Ala Lys Gln Val Val Ile Lys Glu Gly Asp Met Leu Arg Leu Thr 
    130                 135                 140                 


Ser Asp Ala Thr Val His Ser Ile Val Ile Gln Asp Gly Gly Leu Leu 
145                 150                 155                 160 


Val Phe Gly Asp Asn Lys Asp Gly Ser Arg Asn Ile Thr Leu Arg Thr 
                165                 170                 175     


His Tyr Ile Leu Ile Gln Asp Gly Gly Ala Leu His Ile Gly Ala Glu 
            180                 185                 190         


Lys Cys Arg Tyr Lys Ser Lys Ala Thr Ile Thr Leu Tyr Gly Lys Ser 
        195                 200                 205             


Asp Glu Gly Glu Ser Met Pro Thr Phe Gly Lys Lys Phe Ile Gly Val 
    210                 215                 220                 


Glu Ala Gly Gly Thr Leu Glu Leu His Gly Ala Arg Lys Ala Ser Trp 
225                 230                 235                 240 


Thr Leu Leu Ala Arg Thr Leu Asn Ser Ser Gly Leu Pro Phe Gly Ser 
                245                 250                 255     


Tyr Thr Phe Glu Lys Asp Phe Ser Arg Gly Leu Asn Val Arg Val Ile 
            260                 265                 270         


Asp Gln Asp Thr Ala Lys Ile Leu Glu Ser Glu Arg Phe Asp Thr His 
        275                 280                 285             


Glu Tyr Arg Asn Glu Ser Arg Arg Leu Gln Glu Phe Leu Arg Phe Gln 
    290                 295                 300                 


Asp Pro Gly Arg Ile Val Ala Ile Ala Val Gly Asp Ser Ala Ala Lys 
305                 310                 315                 320 


Ser Leu Leu Gln Gly Thr Ile Gln Met Ile Gln Glu Arg Leu Gly Ser 
                325                 330                 335     


Glu Leu Ile Gln Gly Leu Gly Tyr Arg Gln Ala Trp Ala Leu Val Gly 
            340                 345                 350         


Val Ile Asp Gly Gly Ser Thr Ser Cys Asn Glu Ser Val Arg Asn Tyr 
        355                 360                 365             


Glu Asn His Ser Ser Gly Gly Lys Ala Leu Ala Gln Arg Glu Phe Tyr 
    370                 375                 380                 


Thr Val Asp Gly Gln Lys Phe Ser Val Thr Ala Tyr Ser Glu Trp Ile 
385                 390                 395                 400 


Glu Gly Val Ser Leu Ser Gly Phe Arg Val Glu Val Val Asp Gly Val 
                405                 410                 415     


Lys Leu Asn Leu Leu Asp Asp Val Ser Ser Trp Lys Pro Gly Asp Gln 
            420                 425                 430         


Ile Val Val Ala Ser Thr Asp Tyr Ser Met Tyr Gln Ala Glu Glu Phe 
        435                 440                 445             


Thr Leu Leu Pro Cys Ser Glu Cys Ser His Phe Gln Val Lys Val Lys 
    450                 455                 460                 


Glu Thr Pro Gln Phe Leu His Met Gly Glu Ile Ile Asp Gly Val Asp 
465                 470                 475                 480 


Met Arg Ala Glu Val Gly Ile Leu Thr Arg Asn Ile Val Ile Gln Gly 
                485                 490                 495     


Glu Val Glu Asp Ser Cys Tyr Ala Glu Asn Gln Cys Gln Phe Phe Asp 
            500                 505                 510         


Tyr Asp Thr Phe Gly Gly His Ile Met Ile Met Lys Asn Phe Thr Ser 
        515                 520                 525             


Val His Leu Ser Tyr Val Glu Leu Lys His Met Gly Gln Gln Gln Met 
    530                 535                 540                 


Gly Arg Tyr Pro Val His Phe His Leu Cys Gly Asp Val Asp Tyr Lys 
545                 550                 555                 560 


Gly Gly Tyr Arg His Ala Thr Phe Val Asp Gly Leu Ser Ile His His 
                565                 570                 575     


Ser Phe Ser Arg Cys Ile Thr Val His Gly Thr Asn Gly Leu Leu Ile 
            580                 585                 590         


Lys Asp Thr Ile Gly Phe Asp Thr Leu Gly His Cys Phe Phe Leu Glu 
        595                 600                 605             


Asp Gly Ile Glu Gln Arg Asn Thr Leu Phe His Asn Leu Gly Leu Leu 
    610                 615                 620                 


Thr Lys Pro Gly Thr Leu Leu Pro Thr Asp Arg Asn Asn Ser Met Cys 
625                 630                 635                 640 


Thr Thr Met Arg Asp Lys Val Phe Gly Asn Tyr Ile Pro Val Pro Ala 
                645                 650                 655     


Thr Asp Cys Met Ala Val Ser Thr Phe Trp Ile Ala His Pro Asn Asn 
            660                 665                 670         


Asn Leu Ile Asn Asn Ala Ala Ala Gly Ser Gln Asp Ala Gly Ile Trp 
        675                 680                 685             


Tyr Leu Phe His Lys Glu Pro Thr Gly Glu Ser Ser Gly Leu Gln Leu 
    690                 695                 700                 


Leu Ala Lys Pro Glu Leu Thr Pro Leu Gly Ile Phe Tyr Asn Asn Arg 
705                 710                 715                 720 


Val His Ser Asn Phe Lys Ala Gly Leu Phe Ile Asp Lys Gly Val Lys 
                725                 730                 735     


Thr Thr Asn Ser Ser Ala Ala Asp Pro Arg Glu Tyr Leu Cys Leu Asp 
            740                 745                 750         


Asn Ser Ala Arg Phe Arg Pro His Gln Asp Ala Asn Pro Glu Lys Pro 
        755                 760                 765             


Arg Val Ala Ala Leu Ile Asp Arg Leu Ile Ala Phe Lys Asn Asn Asp 
    770                 775                 780                 


Asn Gly Ala Trp Val Arg Gly Gly Asp Ile Ile Val Gln Asn Ser Ala 
785                 790                 795                 800 


Phe Ala Asp Asn Gly Ile Gly Leu Thr Phe Ala Ser Asp Gly Ser Phe 
                805                 810                 815     


Pro Ser Asp Glu Gly Ser Ser Gln Glu Val Ser Glu Ser Leu Phe Val 
            820                 825                 830         


Gly Glu Ser Arg Asn Tyr Gly Phe Gln Gly Gly Gln Asn Lys Tyr Val 
        835                 840                 845             


Gly Thr Gly Gly Ile Asp Gln Lys Pro Arg Thr Leu Pro Arg Asn Arg 
    850                 855                 860                 


Thr Phe Pro Ile Arg Gly Phe Gln Ile Tyr Asp Gly Pro Ile His Leu 
865                 870                 875                 880 


Thr Arg Ser Thr Phe Lys Lys Tyr Val Pro Thr Pro Asp Arg Tyr Ser 
                885                 890                 895     


Ser Ala Ile Gly Phe Leu Met Lys Asn Ser Trp Gln Ile Thr Pro Arg 
            900                 905                 910         


Asn Asn Ile Ser Leu Val Lys Phe Gly Pro His Val Ser Leu Asn Val 
        915                 920                 925             


Phe Phe Gly Lys Pro Gly Pro Trp Phe Glu Asp Cys Glu Met Asp Gly 
    930                 935                 940                 


Asp Lys Asn Ser Ile Phe His Asp Ile Asp Gly Ser Val Thr Gly Tyr 
945                 950                 955                 960 


Lys Asp Ala Tyr Val Gly Arg Met Asp Asn Tyr Leu Ile Arg His Pro 
                965                 970                 975     


Ser Cys Val Asn Val Ser Lys Trp Asn Ala Val Ile Cys Ser Gly Thr 
            980                 985                 990         


Tyr Ala Gln Val Tyr Val Gln Thr  Trp Ser Thr Gln Asn  Leu Ser Met 
        995                 1000                 1005             


Thr Ile  Thr Arg Asp Glu Tyr  Pro Ser Asn Pro Met  Val Leu Arg 
    1010                 1015                 1020             


Gly Ile  Asn Gln Lys Ala Ala  Phe Pro Gln Tyr Gln  Pro Val Val 
    1025                 1030                 1035             


Met Leu  Glu Lys Gly Tyr Thr  Ile His Trp Asn Gly  Pro Ala Pro 
    1040                 1045                 1050             


Arg Thr  Thr Phe Leu Tyr Leu  Val Asn Phe Asn Lys  Asn Asp Trp 
    1055                 1060                 1065             


Ile Arg  Val Gly Leu Cys Tyr  Pro Ser Asn Thr Ser  Phe Gln Val 
    1070                 1075                 1080             


Thr Phe  Gly Tyr Leu Gln Arg  Gln Asn Gly Ser Leu  Ser Lys Ile 
    1085                 1090                 1095             


Glu Glu  Tyr Glu Pro Val His  Ser Leu Glu Glu Leu  Gln Arg Lys 
    1100                 1105                 1110             


Gln Ser  Glu Arg Lys Phe Tyr  Phe Asp Ser Ser Thr  Gly Leu Leu 
    1115                 1120                 1125             


Phe Leu  Tyr Leu Lys Ala Lys  Ser His Arg His Gly  His Ser Tyr 
    1130                 1135                 1140             


Cys Ser  Ser Gln Gly Cys Glu  Arg Val Lys Ile Gln  Ala Ala Thr 
    1145                 1150                 1155             


Asp Ser  Lys Asp Ile Ser Asn  Cys Met Ala Lys Ala  Tyr Pro Gln 
    1160                 1165                 1170             


Tyr Tyr  Arg Lys Pro Ser Val  Val Lys Arg Met Pro  Ala Met Leu 
    1175                 1180                 1185             


Thr Gly  Leu Cys Gln Gly Cys  Gly Thr Arg Gln Val  Val Phe Thr 
    1190                 1195                 1200             


Ser Asp  Pro His Lys Ser Tyr  Leu Pro Val Gln Phe  Gln Ser Pro 
    1205                 1210                 1215             


Asp Lys  Ala Glu Thr Gln Arg  Gly Asp Pro Ser Val  Ile Ser Val 
    1220                 1225                 1230             


Asn Gly  Thr Asp Phe Thr Phe  Arg Ser Ala Gly Val  Leu Leu Leu 
    1235                 1240                 1245             


Val Val  Asp Pro Cys Ser Val  Pro Phe Arg Leu Thr  Glu Lys Thr 
    1250                 1255                 1260             


Val Phe  Pro Leu Ala Asp Val  Ser Arg Ile Glu Glu  Tyr Leu Lys 
    1265                 1270                 1275             


Thr Gly  Ile Pro Pro Arg Ser  Ile Val Leu Leu Ser  Thr Arg Gly 
    1280                 1285                 1290             


Glu Ile  Lys Gln Leu Asn Ile  Ser His Leu Leu Val  Pro Leu Gly 
    1295                 1300                 1305             


Leu Ala  Lys Pro Ala His Leu  Tyr Asp Lys Gly Ser  Thr Ile Phe 
    1310                 1315                 1320             


Leu Gly  Phe Ser Gly Asn Phe  Lys Pro Ser Trp Thr  Lys Leu Phe 
    1325                 1330                 1335             


Thr Ser  Pro Ala Gly Gln Gly  Leu Gly Val Leu Glu  Gln Phe Ile 
    1340                 1345                 1350             


Pro Leu  Gln Leu Asp Glu Tyr  Gly Cys Pro Arg Ala  Thr Thr Val 
    1355                 1360                 1365             


Arg Arg  Arg Asp Leu Glu Leu  Leu Lys Gln Ala Ser  Lys Ala His 
    1370                 1375                 1380             


<210>  4050
<211>  1320
<212>  PRT
<213>  homo sapiens

<400>  4050

Met Tyr Ala Thr Asp Ser Arg Gly His Ser Pro Ala Phe Leu Gln Pro 
1               5                   10                  15      


Gln Asn Gly Asn Ser Arg His Pro Ser Gly Tyr Val Pro Gly Lys Val 
            20                  25                  30          


Val Pro Leu Arg Pro Pro Pro Pro Pro Lys Ser Gln Ala Ser Ala Lys 
        35                  40                  45              


Phe Thr Ser Ile Arg Arg Glu Asp Arg Ala Thr Phe Ala Phe Ser Pro 
    50                  55                  60                  


Glu Glu Gln Gln Ala Gln Arg Glu Ser Gln Lys Gln Lys Arg His Lys 
65                  70                  75                  80  


Asn Thr Phe Ile Cys Phe Ala Ile Thr Ser Phe Ser Phe Phe Ile Ala 
                85                  90                  95      


Leu Ala Ile Ile Leu Gly Ile Ser Ser Lys Tyr Ala Pro Asp Glu Asn 
            100                 105                 110         


Cys Pro Asp Gln Asn Pro Arg Leu Arg Asn Trp Asp Pro Gly Gln Asp 
        115                 120                 125             


Ser Ala Lys Gln Val Val Ile Lys Glu Gly Asp Met Leu Arg Leu Thr 
    130                 135                 140                 


Ser Asp Ala Thr Val His Ser Ile Val Ile Gln Asp Gly Gly Leu Leu 
145                 150                 155                 160 


Val Phe Gly Asp Asn Lys Asp Gly Ser Arg Asn Ile Thr Leu Arg Thr 
                165                 170                 175     


His Tyr Ile Leu Ile Gln Asp Gly Gly Ala Leu His Ile Gly Ala Glu 
            180                 185                 190         


Lys Cys Arg Tyr Lys Ser Lys Ala Thr Ile Thr Leu Tyr Gly Lys Ser 
        195                 200                 205             


Asp Glu Gly Glu Ser Met Pro Thr Phe Gly Lys Lys Phe Ile Gly Val 
    210                 215                 220                 


Glu Ala Gly Gly Thr Leu Glu Leu His Gly Ala Arg Lys Ala Ser Trp 
225                 230                 235                 240 


Thr Leu Leu Ala Arg Thr Leu Asn Ser Ser Gly Leu Pro Phe Gly Ser 
                245                 250                 255     


Tyr Thr Phe Glu Lys Asp Phe Ser Arg Gly Leu Asn Val Arg Val Ile 
            260                 265                 270         


Asp Gln Asp Thr Ala Lys Ile Leu Glu Ser Glu Arg Phe Asp Thr His 
        275                 280                 285             


Glu Tyr Arg Asn Glu Ser Arg Arg Leu Gln Glu Phe Leu Arg Phe Gln 
    290                 295                 300                 


Asp Pro Gly Arg Ile Val Ala Ile Ala Val Gly Asp Ser Ala Ala Lys 
305                 310                 315                 320 


Ser Leu Leu Gln Gly Thr Ile Gln Met Ile Gln Glu Arg Leu Gly Ser 
                325                 330                 335     


Glu Leu Ile Gln Gly Leu Gly Tyr Arg Gln Ala Trp Ala Leu Val Gly 
            340                 345                 350         


Val Ile Asp Gly Gly Ser Thr Ser Cys Asn Glu Ser Val Arg Asn Tyr 
        355                 360                 365             


Glu Asn His Ser Ser Gly Gly Lys Ala Leu Ala Gln Arg Glu Phe Tyr 
    370                 375                 380                 


Thr Val Asp Gly Gln Lys Phe Ser Val Thr Ala Tyr Ser Glu Trp Ile 
385                 390                 395                 400 


Glu Glu Thr Pro Gln Phe Leu His Met Gly Glu Ile Ile Asp Gly Val 
                405                 410                 415     


Asp Met Arg Ala Glu Val Gly Ile Leu Thr Arg Asn Ile Val Ile Gln 
            420                 425                 430         


Gly Glu Val Glu Asp Ser Cys Tyr Ala Glu Asn Gln Cys Gln Phe Phe 
        435                 440                 445             


Asp Tyr Asp Thr Phe Gly Gly His Ile Met Ile Met Lys Asn Phe Thr 
    450                 455                 460                 


Ser Val His Leu Ser Tyr Val Glu Leu Lys His Met Gly Gln Gln Gln 
465                 470                 475                 480 


Met Gly Arg Tyr Pro Val His Phe His Leu Cys Gly Asp Val Asp Tyr 
                485                 490                 495     


Lys Gly Gly Tyr Arg His Ala Thr Phe Val Asp Gly Leu Ser Ile His 
            500                 505                 510         


His Ser Phe Ser Arg Cys Ile Thr Val His Gly Thr Asn Gly Leu Leu 
        515                 520                 525             


Ile Lys Asp Thr Ile Gly Phe Asp Thr Leu Gly His Cys Phe Phe Leu 
    530                 535                 540                 


Glu Asp Gly Ile Glu Gln Arg Asn Thr Leu Phe His Asn Leu Gly Leu 
545                 550                 555                 560 


Leu Thr Lys Pro Gly Thr Leu Leu Pro Thr Asp Arg Asn Asn Ser Met 
                565                 570                 575     


Cys Thr Thr Met Arg Asp Lys Val Phe Gly Asn Tyr Ile Pro Val Pro 
            580                 585                 590         


Ala Thr Asp Cys Met Ala Val Ser Thr Phe Trp Ile Ala His Pro Asn 
        595                 600                 605             


Asn Asn Leu Ile Asn Asn Ala Ala Ala Gly Ser Gln Asp Ala Gly Ile 
    610                 615                 620                 


Trp Tyr Leu Phe His Lys Glu Pro Thr Gly Glu Ser Ser Gly Leu Gln 
625                 630                 635                 640 


Leu Leu Ala Lys Pro Glu Leu Thr Pro Leu Gly Ile Phe Tyr Asn Asn 
                645                 650                 655     


Arg Val His Ser Asn Phe Lys Ala Gly Leu Phe Ile Asp Lys Gly Val 
            660                 665                 670         


Lys Thr Thr Asn Ser Ser Ala Ala Asp Pro Arg Glu Tyr Leu Cys Leu 
        675                 680                 685             


Asp Asn Ser Ala Arg Phe Arg Pro His Gln Asp Ala Asn Pro Glu Lys 
    690                 695                 700                 


Pro Arg Val Ala Ala Leu Ile Asp Arg Leu Ile Ala Phe Lys Asn Asn 
705                 710                 715                 720 


Asp Asn Gly Ala Trp Val Arg Gly Gly Asp Ile Ile Val Gln Asn Ser 
                725                 730                 735     


Ala Phe Ala Asp Asn Gly Ile Gly Leu Thr Phe Ala Ser Asp Gly Ser 
            740                 745                 750         


Phe Pro Ser Asp Glu Gly Ser Ser Gln Glu Val Ser Glu Ser Leu Phe 
        755                 760                 765             


Val Gly Glu Ser Arg Asn Tyr Gly Phe Gln Gly Gly Gln Asn Lys Tyr 
    770                 775                 780                 


Val Gly Thr Gly Gly Ile Asp Gln Lys Pro Arg Thr Leu Pro Arg Asn 
785                 790                 795                 800 


Arg Thr Phe Pro Ile Arg Gly Phe Gln Ile Tyr Asp Gly Pro Ile His 
                805                 810                 815     


Leu Thr Arg Ser Thr Phe Lys Lys Tyr Val Pro Thr Pro Asp Arg Tyr 
            820                 825                 830         


Ser Ser Ala Ile Gly Phe Leu Met Lys Asn Ser Trp Gln Ile Thr Pro 
        835                 840                 845             


Arg Asn Asn Ile Ser Leu Val Lys Phe Gly Pro His Val Ser Leu Asn 
    850                 855                 860                 


Val Phe Phe Gly Lys Pro Gly Pro Trp Phe Glu Asp Cys Glu Met Asp 
865                 870                 875                 880 


Gly Asp Lys Asn Ser Ile Phe His Asp Ile Asp Gly Ser Val Thr Gly 
                885                 890                 895     


Tyr Lys Asp Ala Tyr Val Gly Arg Met Asp Asn Tyr Leu Ile Arg His 
            900                 905                 910         


Pro Ser Cys Val Asn Val Ser Lys Trp Asn Ala Val Ile Cys Ser Gly 
        915                 920                 925             


Thr Tyr Ala Gln Val Tyr Val Gln Thr Trp Ser Thr Gln Asn Leu Ser 
    930                 935                 940                 


Met Thr Ile Thr Arg Asp Glu Tyr Pro Ser Asn Pro Met Val Leu Arg 
945                 950                 955                 960 


Gly Ile Asn Gln Lys Ala Ala Phe Pro Gln Tyr Gln Pro Val Val Met 
                965                 970                 975     


Leu Glu Lys Gly Tyr Thr Ile His Trp Asn Gly Pro Ala Pro Arg Thr 
            980                 985                 990         


Thr Phe Leu Tyr Leu Val Asn Phe  Asn Lys Asn Asp Trp  Ile Arg Val 
        995                 1000                 1005             


Gly Leu  Cys Tyr Pro Ser Asn  Thr Ser Phe Gln Val  Thr Phe Gly 
    1010                 1015                 1020             


Tyr Leu  Gln Arg Gln Asn Gly  Ser Leu Ser Lys Ile  Glu Glu Tyr 
    1025                 1030                 1035             


Glu Pro  Val His Ser Leu Glu  Glu Leu Gln Arg Lys  Gln Ser Glu 
    1040                 1045                 1050             


Arg Lys  Phe Tyr Phe Asp Ser  Ser Thr Gly Leu Leu  Phe Leu Tyr 
    1055                 1060                 1065             


Leu Lys  Ala Lys Ser His Arg  His Gly His Ser Tyr  Cys Ser Ser 
    1070                 1075                 1080             


Gln Gly  Cys Glu Arg Val Lys  Ile Gln Ala Ala Thr  Asp Ser Lys 
    1085                 1090                 1095             


Asp Ile  Ser Asn Cys Met Ala  Lys Ala Tyr Pro Gln  Tyr Tyr Arg 
    1100                 1105                 1110             


Lys Pro  Ser Val Val Lys Arg  Met Pro Ala Met Leu  Thr Gly Leu 
    1115                 1120                 1125             


Cys Gln  Gly Cys Gly Thr Arg  Gln Val Val Phe Thr  Ser Asp Pro 
    1130                 1135                 1140             


His Lys  Ser Tyr Leu Pro Val  Gln Phe Gln Ser Pro  Asp Lys Ala 
    1145                 1150                 1155             


Glu Thr  Gln Arg Gly Asp Pro  Ser Val Ile Ser Val  Asn Gly Thr 
    1160                 1165                 1170             


Asp Phe  Thr Phe Arg Ser Ala  Gly Val Leu Leu Leu  Val Val Asp 
    1175                 1180                 1185             


Pro Cys  Ser Val Pro Phe Arg  Leu Thr Glu Lys Thr  Val Phe Pro 
    1190                 1195                 1200             


Leu Ala  Asp Val Ser Arg Ile  Glu Glu Tyr Leu Lys  Thr Gly Ile 
    1205                 1210                 1215             


Pro Pro  Arg Ser Ile Val Leu  Leu Ser Thr Arg Gly  Glu Ile Lys 
    1220                 1225                 1230             


Gln Leu  Asn Ile Ser His Leu  Leu Val Pro Leu Gly  Leu Ala Lys 
    1235                 1240                 1245             


Pro Ala  His Leu Tyr Asp Lys  Gly Ser Thr Ile Phe  Leu Gly Phe 
    1250                 1255                 1260             


Ser Gly  Asn Phe Lys Pro Ser  Trp Thr Lys Leu Phe  Thr Ser Pro 
    1265                 1270                 1275             


Ala Gly  Gln Gly Leu Gly Val  Leu Glu Gln Phe Ile  Pro Leu Gln 
    1280                 1285                 1290             


Leu Asp  Glu Tyr Gly Cys Pro  Arg Ala Thr Thr Val  Arg Arg Arg 
    1295                 1300                 1305             


Asp Leu  Glu Leu Leu Lys Gln  Ala Ser Lys Ala His  
    1310                 1315                 1320 


<210>  4051
<211>  253
<212>  PRT
<213>  homo sapiens

<400>  4051

Met Met Ala Gln Ser Lys Ala Asn Gly Ser His Tyr Ala Leu Thr Ala 
1               5                   10                  15      


Ile Gly Leu Gly Met Leu Val Leu Gly Val Ile Met Ala Met Trp Asn 
            20                  25                  30          


Leu Val Pro Gly Phe Ser Ala Ala Glu Lys Pro Thr Ala Gln Gly Ser 
        35                  40                  45              


Asn Lys Thr Glu Val Gly Gly Gly Ile Leu Lys Ser Lys Thr Phe Ser 
    50                  55                  60                  


Val Ala Tyr Val Leu Val Gly Ala Gly Val Met Leu Leu Leu Leu Ser 
65                  70                  75                  80  


Ile Cys Leu Ser Ile Arg Asp Lys Arg Lys Gln Arg Gln Gly Glu Asp 
                85                  90                  95      


Leu Ala His Val Gln His Pro Thr Gly Ala Gly Pro His Ala Gln Glu 
            100                 105                 110         


Glu Asp Ser Gln Glu Glu Glu Glu Glu Asp Glu Glu Ala Ala Ser Arg 
        115                 120                 125             


Tyr Tyr Val Pro Ser Tyr Glu Glu Val Met Asn Thr Asn Tyr Ser Glu 
    130                 135                 140                 


Ala Arg Gly Glu Glu Gln Asn Pro Arg Leu Ser Ile Ser Leu Pro Ser 
145                 150                 155                 160 


Tyr Glu Ser Leu Thr Gly Leu Asp Glu Thr Thr Pro Thr Ser Thr Arg 
                165                 170                 175     


Ala Asp Val Glu Ala Ser Pro Gly Asn Pro Pro Asp Arg Gln Asn Ser 
            180                 185                 190         


Lys Leu Ala Lys Arg Leu Lys Pro Leu Lys Val Arg Arg Ile Lys Ser 
        195                 200                 205             


Glu Lys Leu His Leu Lys Asp Phe Arg Ile Asn Leu Pro Asp Lys Asn 
    210                 215                 220                 


Val Pro Pro Pro Ser Ile Glu Pro Leu Thr Pro Pro Pro Gln Tyr Asp 
225                 230                 235                 240 


Glu Val Gln Glu Lys Ala Pro Asp Thr Arg Pro Pro Asp 
                245                 250             


<210>  4052
<211>  253
<212>  PRT
<213>  homo sapiens

<400>  4052

Met Met Ala Gln Ser Lys Ala Asn Gly Ser His Tyr Ala Leu Thr Ala 
1               5                   10                  15      


Ile Gly Leu Gly Met Leu Val Leu Gly Val Ile Met Ala Met Trp Asn 
            20                  25                  30          


Leu Val Pro Gly Phe Ser Ala Ala Glu Lys Pro Thr Ala Gln Gly Ser 
        35                  40                  45              


Asn Lys Thr Glu Val Gly Gly Gly Ile Leu Lys Ser Lys Thr Phe Ser 
    50                  55                  60                  


Val Ala Tyr Val Leu Val Gly Ala Gly Val Met Leu Leu Leu Leu Ser 
65                  70                  75                  80  


Ile Cys Leu Ser Ile Arg Asp Lys Arg Lys Gln Arg Gln Gly Glu Asp 
                85                  90                  95      


Leu Ala His Val Gln His Pro Thr Gly Ala Gly Pro His Ala Gln Glu 
            100                 105                 110         


Glu Asp Ser Gln Glu Glu Glu Glu Glu Asp Glu Glu Ala Ala Ser Arg 
        115                 120                 125             


Tyr Tyr Val Pro Ser Tyr Glu Glu Val Met Asn Thr Asn Tyr Ser Glu 
    130                 135                 140                 


Ala Arg Gly Glu Glu Gln Asn Pro Arg Leu Ser Ile Ser Leu Pro Ser 
145                 150                 155                 160 


Tyr Glu Ser Leu Thr Gly Leu Asp Glu Thr Thr Pro Thr Ser Thr Arg 
                165                 170                 175     


Ala Asp Val Glu Ala Ser Pro Gly Asn Pro Pro Asp Arg Gln Asn Ser 
            180                 185                 190         


Lys Leu Ala Lys Arg Leu Lys Pro Leu Lys Val Arg Arg Ile Lys Ser 
        195                 200                 205             


Glu Lys Leu His Leu Lys Asp Phe Arg Ile Asn Leu Pro Asp Lys Asn 
    210                 215                 220                 


Val Pro Pro Pro Ser Ile Glu Pro Leu Thr Pro Pro Pro Gln Tyr Asp 
225                 230                 235                 240 


Glu Val Gln Glu Lys Ala Pro Asp Thr Arg Pro Pro Asp 
                245                 250             


<210>  4053
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  4053

Met Ala Ser Gln Pro Pro Glu Asp Thr Ala Glu Ser Gln Ala Ser Asp 
1               5                   10                  15      


Glu Leu Glu Cys Lys Ile Cys Tyr Asn Arg Tyr Asn Leu Lys Gln Arg 
            20                  25                  30          


Lys Pro Lys Val Leu Glu Cys Cys His Arg Val Cys Ala Lys Cys Leu 
        35                  40                  45              


Tyr Lys Ile Ile Asp Phe Gly Asp Ser Pro Gln Gly Val Ile Val Cys 
    50                  55                  60                  


Pro Phe Cys Arg Phe Glu Thr Cys Leu Pro Asp Asp Glu Val Ser Ser 
65                  70                  75                  80  


Leu Pro Asp Asp Asn Asn Ile Leu Val Asn Leu Thr Cys Gly Gly Lys 
                85                  90                  95      


Gly Lys Lys Cys Leu Pro Glu Asn Pro Thr Glu Leu Leu Leu Thr Pro 
            100                 105                 110         


Lys Arg Leu Ala Ser Leu Val Ser Pro Ser His Thr Ser Ser Asn Cys 
        115                 120                 125             


Leu Val Ile Thr Ile Met Glu Val Gln Arg Glu Ser Ser Pro Ser Leu 
    130                 135                 140                 


Ser Ser Thr Pro Val Val Glu Phe Tyr Arg Pro Ala Ser Phe Asp Ser 
145                 150                 155                 160 


Val Thr Thr Val Ser His Asn Trp Thr Val Trp Asn Cys Thr Ser Leu 
                165                 170                 175     


Leu Phe Gln Thr Ser Ile Arg Val Leu Val Trp Leu Leu Gly Leu Leu 
            180                 185                 190         


Tyr Phe Ser Ser Leu Pro Leu Gly Ile Tyr Leu Leu Val Ser Lys Lys 
        195                 200                 205             


Val Thr Leu Gly Val Val Phe Val Ser Leu Val Pro Ser Ser Leu Val 
    210                 215                 220                 


Ile Leu Met Val Tyr Gly Phe Cys Gln Cys Val Cys His Glu Phe Leu 
225                 230                 235                 240 


Asp Cys Met Ala Pro Pro Ser 
                245         


<210>  4054
<211>  521
<212>  PRT
<213>  homo sapiens

<400>  4054

Met Thr Ser Ala Phe Lys Leu Asp Phe Leu Pro Asp Met Met Val Glu 
1               5                   10                  15      


Gly Arg Leu Leu Val Pro Asp Arg Ile Asn Gly Thr Ala Asn Lys Met 
            20                  25                  30          


Asn Gly Ala Leu Asp His Ser Asp Gln Pro Asp Pro Asp Ala Ile Lys 
        35                  40                  45              


Met Phe Val Gly Gln Ile Pro Arg Ser Trp Ser Glu Lys Glu Leu Lys 
    50                  55                  60                  


Glu Leu Phe Glu Pro Tyr Gly Ala Val Tyr Gln Ile Asn Val Leu Arg 
65                  70                  75                  80  


Asp Arg Ser Gln Asn Pro Pro Gln Ser Lys Gly Cys Cys Phe Val Thr 
                85                  90                  95      


Phe Tyr Thr Arg Lys Ala Ala Leu Glu Ala Gln Asn Ala Leu His Asn 
            100                 105                 110         


Ile Lys Thr Leu Pro Gly Met His His Pro Ile Gln Met Lys Pro Ala 
        115                 120                 125             


Asp Ser Glu Lys Ser Asn Ala Val Glu Asp Arg Lys Leu Phe Ile Gly 
    130                 135                 140                 


Met Val Ser Lys Lys Cys Asn Glu Asn Asp Ile Arg Val Met Phe Ser 
145                 150                 155                 160 


Pro Phe Gly Gln Ile Glu Glu Cys Arg Ile Leu Arg Gly Pro Asp Gly 
                165                 170                 175     


Leu Ser Arg Gly Cys Ala Phe Val Thr Phe Ser Thr Arg Ala Met Ala 
            180                 185                 190         


Gln Asn Ala Ile Lys Ala Met His Gln Ser Gln Thr Met Glu Gly Cys 
        195                 200                 205             


Ser Ser Pro Ile Val Val Lys Phe Ala Asp Thr Gln Lys Asp Lys Glu 
    210                 215                 220                 


Gln Arg Arg Leu Gln Gln Gln Leu Ala Gln Gln Met Gln Gln Leu Asn 
225                 230                 235                 240 


Thr Ala Thr Trp Gly Asn Leu Thr Gly Leu Gly Gly Leu Thr Pro Gln 
                245                 250                 255     


Tyr Leu Ala Leu Leu Gln Gln Ala Thr Ser Ser Ser Asn Leu Gly Ala 
            260                 265                 270         


Phe Ser Gly Ile Gln Gln Met Ala Gly Met Asn Ala Leu Gln Leu Gln 
        275                 280                 285             


Asn Leu Ala Thr Leu Ala Ala Ala Ala Ala Ala Ala Gln Thr Ser Ala 
    290                 295                 300                 


Thr Ser Thr Asn Ala Asn Pro Leu Ser Thr Thr Ser Ser Ala Leu Gly 
305                 310                 315                 320 


Ala Leu Thr Ser Pro Val Ala Ala Ser Thr Pro Asn Ser Thr Ala Gly 
                325                 330                 335     


Ala Ala Met Asn Ser Leu Thr Ser Leu Gly Thr Leu Gln Gly Leu Ala 
            340                 345                 350         


Gly Ala Thr Val Gly Leu Asn Asn Ile Asn Ala Leu Ala Val Ala Gln 
        355                 360                 365             


Met Leu Ser Gly Met Ala Ala Leu Asn Gly Gly Leu Gly Ala Thr Gly 
    370                 375                 380                 


Leu Thr Asn Gly Thr Ala Gly Thr Met Asp Ala Leu Thr Gln Ala Tyr 
385                 390                 395                 400 


Ser Gly Ile Gln Gln Tyr Ala Ala Ala Ala Leu Pro Thr Leu Tyr Ser 
                405                 410                 415     


Gln Ser Leu Leu Gln Gln Gln Ser Ala Ala Gly Ser Gln Lys Glu Gly 
            420                 425                 430         


Pro Glu Gly Ala Asn Leu Phe Ile Tyr His Leu Pro Gln Glu Phe Gly 
        435                 440                 445             


Asp Gln Asp Ile Leu Gln Met Phe Met Pro Phe Gly Asn Val Ile Ser 
    450                 455                 460                 


Ala Lys Val Phe Ile Asp Lys Gln Thr Asn Leu Ser Lys Cys Phe Gly 
465                 470                 475                 480 


Phe Val Ser Tyr Asp Asn Pro Val Ser Ala Gln Ala Ala Ile Gln Ala 
                485                 490                 495     


Met Asn Gly Phe Gln Ile Gly Met Lys Arg Leu Lys Val Gln Leu Lys 
            500                 505                 510         


Arg Ser Lys Asn Asp Ser Lys Pro Tyr 
        515                 520     


<210>  4055
<211>  488
<212>  PRT
<213>  homo sapiens

<400>  4055

Met Asn Gly Ala Leu Asp His Ser Asp Gln Pro Asp Pro Asp Ala Ile 
1               5                   10                  15      


Lys Met Phe Val Gly Gln Ile Pro Arg Ser Trp Ser Glu Lys Glu Leu 
            20                  25                  30          


Lys Glu Leu Phe Glu Pro Tyr Gly Ala Val Tyr Gln Ile Asn Val Leu 
        35                  40                  45              


Arg Asp Arg Ser Gln Asn Pro Pro Gln Ser Lys Gly Cys Cys Phe Val 
    50                  55                  60                  


Thr Phe Tyr Thr Arg Lys Ala Ala Leu Glu Ala Gln Asn Ala Leu His 
65                  70                  75                  80  


Asn Ile Lys Thr Leu Pro Gly Met His His Pro Ile Gln Met Lys Pro 
                85                  90                  95      


Ala Asp Ser Glu Lys Ser Asn Ala Val Glu Asp Arg Lys Leu Phe Ile 
            100                 105                 110         


Gly Met Val Ser Lys Lys Cys Asn Glu Asn Asp Ile Arg Val Met Phe 
        115                 120                 125             


Ser Pro Phe Gly Gln Ile Glu Glu Cys Arg Ile Leu Arg Gly Pro Asp 
    130                 135                 140                 


Gly Leu Ser Arg Gly Cys Ala Phe Val Thr Phe Ser Thr Arg Ala Met 
145                 150                 155                 160 


Ala Gln Asn Ala Ile Lys Ala Met His Gln Ser Gln Thr Met Glu Gly 
                165                 170                 175     


Cys Ser Ser Pro Ile Val Val Lys Phe Ala Asp Thr Gln Lys Asp Lys 
            180                 185                 190         


Glu Gln Arg Arg Leu Gln Gln Gln Leu Ala Gln Gln Met Gln Gln Leu 
        195                 200                 205             


Asn Thr Ala Thr Trp Gly Asn Leu Thr Gly Leu Gly Gly Leu Thr Pro 
    210                 215                 220                 


Gln Tyr Leu Ala Leu Leu Gln Gln Ala Thr Ser Ser Ser Asn Leu Gly 
225                 230                 235                 240 


Ala Phe Ser Gly Ile Gln Gln Met Ala Gly Met Asn Ala Leu Gln Leu 
                245                 250                 255     


Gln Asn Leu Ala Thr Leu Ala Ala Ala Ala Ala Ala Ala Gln Thr Ser 
            260                 265                 270         


Ala Thr Ser Thr Asn Ala Asn Pro Leu Ser Thr Thr Ser Ser Ala Leu 
        275                 280                 285             


Gly Ala Leu Thr Ser Pro Val Ala Ala Ser Thr Pro Asn Ser Thr Ala 
    290                 295                 300                 


Gly Ala Ala Met Asn Ser Leu Thr Ser Leu Gly Thr Leu Gln Gly Leu 
305                 310                 315                 320 


Ala Gly Ala Thr Val Gly Leu Asn Asn Ile Asn Ala Leu Ala Gly Thr 
                325                 330                 335     


Ile Asn Ser Met Ala Ala Leu Asn Gly Gly Leu Gly Ala Thr Gly Leu 
            340                 345                 350         


Thr Asn Gly Thr Ala Gly Thr Met Asp Ala Leu Thr Gln Ala Tyr Ser 
        355                 360                 365             


Gly Ile Gln Gln Tyr Ala Ala Ala Ala Leu Pro Thr Leu Tyr Ser Gln 
    370                 375                 380                 


Ser Leu Leu Gln Gln Gln Ser Ala Ala Gly Ser Gln Lys Glu Gly Pro 
385                 390                 395                 400 


Glu Gly Ala Asn Leu Phe Ile Tyr His Leu Pro Gln Glu Phe Gly Asp 
                405                 410                 415     


Gln Asp Ile Leu Gln Met Phe Met Pro Phe Gly Asn Val Ile Ser Ala 
            420                 425                 430         


Lys Val Phe Ile Asp Lys Gln Thr Asn Leu Ser Lys Cys Phe Gly Phe 
        435                 440                 445             


Val Ser Tyr Asp Asn Pro Val Ser Ala Gln Ala Ala Ile Gln Ala Met 
    450                 455                 460                 


Asn Gly Phe Gln Ile Gly Met Lys Arg Leu Lys Val Gln Leu Lys Arg 
465                 470                 475                 480 


Ser Lys Asn Asp Ser Lys Pro Tyr 
                485             


<210>  4056
<211>  1170
<212>  PRT
<213>  homo sapiens

<400>  4056

Met Thr Asn Pro Ser Asp Arg Val Leu Pro Ala Asn Ser Met Ala Glu 
1               5                   10                  15      


Ser Arg Glu Gly Asp Phe Gly Cys Thr Val Met Glu Leu Arg Lys Leu 
            20                  25                  30          


Met Glu Leu Arg Ser Arg Asp Ala Leu Thr Gln Ile Asn Val His Tyr 
        35                  40                  45              


Gly Gly Val Gln Asn Leu Cys Ser Arg Leu Lys Thr Ser Pro Val Glu 
    50                  55                  60                  


Gly Leu Ser Gly Asn Pro Ala Asp Leu Glu Lys Arg Arg Gln Val Phe 
65                  70                  75                  80  


Gly His Asn Val Ile Pro Pro Lys Lys Pro Lys Thr Phe Leu Glu Leu 
                85                  90                  95      


Val Trp Glu Ala Leu Gln Asp Val Thr Leu Ile Ile Leu Glu Ile Ala 
            100                 105                 110         


Ala Ile Ile Ser Leu Val Leu Ser Phe Tyr Arg Pro Ala Gly Glu Glu 
        115                 120                 125             


Asn Glu Leu Cys Gly Gln Val Ala Thr Thr Pro Glu Asp Glu Asn Glu 
    130                 135                 140                 


Ala Gln Ala Gly Trp Ile Glu Gly Ala Ala Ile Leu Phe Ser Val Ile 
145                 150                 155                 160 


Ile Val Val Leu Val Thr Ala Phe Asn Asp Trp Ser Lys Glu Lys Gln 
                165                 170                 175     


Phe Arg Gly Leu Gln Cys Arg Ile Glu Gln Glu Gln Lys Phe Ser Ile 
            180                 185                 190         


Ile Arg Asn Gly Gln Leu Ile Gln Leu Pro Val Ala Glu Ile Val Val 
        195                 200                 205             


Gly Asp Ile Ala Gln Val Lys Tyr Gly Asp Leu Leu Pro Ala Asp Gly 
    210                 215                 220                 


Ile Leu Ile Gln Gly Asn Asp Leu Lys Ile Asp Glu Ser Ser Leu Thr 
225                 230                 235                 240 


Gly Glu Ser Asp His Val Lys Lys Ser Leu Asp Lys Asp Pro Met Leu 
                245                 250                 255     


Leu Ser Gly Thr His Val Met Glu Gly Ser Gly Arg Met Val Val Thr 
            260                 265                 270         


Ala Val Gly Val Asn Ser Gln Thr Gly Ile Ile Leu Thr Leu Leu Gly 
        275                 280                 285             


Val Asn Glu Asp Asp Glu Gly Glu Lys Lys Lys Lys Gly Lys Lys Gln 
    290                 295                 300                 


Gly Val Pro Glu Asn Arg Asn Lys Ala Lys Thr Gln Asp Gly Val Ala 
305                 310                 315                 320 


Leu Glu Ile Gln Pro Leu Asn Ser Gln Glu Gly Ile Asp Asn Glu Glu 
                325                 330                 335     


Lys Asp Lys Lys Ala Val Lys Val Pro Lys Lys Glu Lys Ser Val Leu 
            340                 345                 350         


Gln Gly Lys Leu Thr Arg Leu Ala Val Gln Ile Gly Lys Ala Gly Leu 
        355                 360                 365             


Leu Met Ser Ala Leu Thr Val Phe Ile Leu Ile Leu Tyr Phe Val Ile 
    370                 375                 380                 


Asp Asn Phe Val Ile Asn Arg Arg Pro Trp Leu Pro Glu Cys Thr Pro 
385                 390                 395                 400 


Ile Tyr Ile Gln Tyr Phe Val Lys Phe Phe Ile Ile Gly Ile Thr Val 
                405                 410                 415     


Leu Val Val Ala Val Pro Glu Gly Leu Pro Leu Ala Val Thr Ile Ser 
            420                 425                 430         


Leu Ala Tyr Ser Val Lys Lys Met Met Lys Asp Asn Asn Leu Val Arg 
        435                 440                 445             


His Leu Asp Ala Cys Glu Thr Met Gly Asn Ala Thr Ala Ile Cys Ser 
    450                 455                 460                 


Asp Lys Thr Gly Thr Leu Thr Met Asn Arg Met Thr Val Val Gln Ala 
465                 470                 475                 480 


Tyr Ile Gly Gly Ile His Tyr Arg Gln Ile Pro Ser Pro Asp Val Phe 
                485                 490                 495     


Leu Pro Lys Val Leu Asp Leu Ile Val Asn Gly Ile Ser Ile Asn Ser 
            500                 505                 510         


Ala Tyr Thr Ser Lys Ile Leu Pro Pro Glu Lys Glu Gly Gly Leu Pro 
        515                 520                 525             


Arg Gln Val Gly Asn Lys Thr Glu Cys Ala Leu Leu Gly Phe Val Thr 
    530                 535                 540                 


Asp Leu Lys Gln Asp Tyr Gln Ala Val Arg Asn Glu Val Pro Glu Glu 
545                 550                 555                 560 


Lys Leu Tyr Lys Val Tyr Thr Phe Asn Ser Val Arg Lys Ser Met Ser 
                565                 570                 575     


Thr Val Ile Arg Asn Pro Asn Gly Gly Phe Arg Met Tyr Ser Lys Gly 
            580                 585                 590         


Ala Ser Glu Ile Ile Leu Arg Lys Cys Asn Arg Ile Leu Asp Arg Lys 
        595                 600                 605             


Gly Glu Ala Val Pro Phe Lys Asn Lys Asp Arg Asp Asp Met Val Arg 
    610                 615                 620                 


Thr Val Ile Glu Pro Met Ala Cys Asp Gly Leu Arg Thr Ile Cys Ile 
625                 630                 635                 640 


Ala Tyr Arg Asp Phe Asp Asp Thr Glu Pro Ser Trp Asp Asn Glu Asn 
                645                 650                 655     


Glu Ile Leu Thr Glu Leu Thr Cys Ile Ala Val Val Gly Ile Glu Asp 
            660                 665                 670         


Pro Val Arg Pro Glu Val Pro Asp Ala Ile Ala Lys Cys Lys Gln Ala 
        675                 680                 685             


Gly Ile Thr Val Arg Met Val Thr Gly Asp Asn Ile Asn Thr Ala Arg 
    690                 695                 700                 


Ala Ile Ala Thr Lys Cys Gly Ile Leu Thr Pro Gly Asp Asp Phe Leu 
705                 710                 715                 720 


Cys Leu Glu Gly Lys Glu Phe Asn Arg Leu Ile Arg Asn Glu Lys Gly 
                725                 730                 735     


Glu Val Glu Gln Glu Lys Leu Asp Lys Ile Trp Pro Lys Leu Arg Val 
            740                 745                 750         


Leu Ala Arg Ser Ser Pro Thr Asp Lys His Thr Leu Val Lys Gly Ile 
        755                 760                 765             


Ile Asp Ser Thr Val Gly Glu His Arg Gln Val Val Ala Val Thr Gly 
    770                 775                 780                 


Asp Gly Thr Asn Asp Gly Pro Ala Leu Lys Lys Ala Asp Val Gly Phe 
785                 790                 795                 800 


Ala Met Gly Ile Ala Gly Thr Asp Val Ala Lys Glu Ala Ser Asp Ile 
                805                 810                 815     


Ile Leu Thr Asp Asp Asn Phe Thr Ser Ile Val Lys Ala Val Met Trp 
            820                 825                 830         


Gly Arg Asn Val Tyr Asp Ser Ile Ser Lys Phe Leu Gln Phe Gln Leu 
        835                 840                 845             


Thr Val Asn Val Val Ala Val Ile Val Ala Phe Thr Gly Ala Cys Ile 
    850                 855                 860                 


Thr Gln Asp Ser Pro Leu Lys Ala Val Gln Met Leu Trp Val Asn Leu 
865                 870                 875                 880 


Ile Met Asp Thr Phe Ala Ser Leu Ala Leu Ala Thr Glu Pro Pro Thr 
                885                 890                 895     


Glu Ser Leu Leu Lys Arg Arg Pro Tyr Gly Arg Asn Lys Pro Leu Ile 
            900                 905                 910         


Ser Arg Thr Met Met Lys Asn Ile Leu Gly His Ala Phe Tyr Gln Leu 
        915                 920                 925             


Ile Val Ile Phe Ile Leu Val Phe Ala Gly Glu Lys Phe Phe Asp Ile 
    930                 935                 940                 


Asp Ser Gly Arg Lys Ala Pro Leu His Ser Pro Pro Ser Gln His Tyr 
945                 950                 955                 960 


Thr Ile Val Phe Asn Thr Phe Val Leu Met Gln Leu Phe Asn Glu Ile 
                965                 970                 975     


Asn Ser Arg Lys Ile His Gly Glu Lys Asn Val Phe Ser Gly Ile Tyr 
            980                 985                 990         


Arg Asn Ile Ile Phe Cys Ser Val  Val Leu Gly Thr Phe  Ile Cys Gln 
        995                 1000                 1005             


Ile Phe  Ile Val Glu Phe Gly  Gly Lys Pro Phe Ser  Cys Thr Ser 
    1010                 1015                 1020             


Leu Ser  Leu Ser Gln Trp Leu  Trp Cys Leu Phe Ile  Gly Ile Gly 
    1025                 1030                 1035             


Glu Leu  Leu Trp Gly Gln Phe  Ile Ser Ala Ile Pro  Thr Arg Ser 
    1040                 1045                 1050             


Leu Lys  Phe Leu Lys Glu Ala  Gly His Gly Thr Thr  Lys Glu Glu 
    1055                 1060                 1065             


Ile Thr  Lys Asp Ala Glu Gly  Leu Asp Glu Ile Asp  His Ala Glu 
    1070                 1075                 1080             


Met Glu  Leu Arg Arg Gly Gln  Ile Leu Trp Phe Arg  Gly Leu Asn 
    1085                 1090                 1095             


Arg Ile  Gln Thr Gln Ile Asp  Val Ile Asn Thr Phe  Gln Thr Gly 
    1100                 1105                 1110             


Ala Ser  Phe Lys Gly Val Leu  Arg Arg Gln Asn Met  Gly Gln His 
    1115                 1120                 1125             


Leu Asp  Val Lys Leu Val Pro  Ser Ser Ser Tyr Val  Ala Val Ala 
    1130                 1135                 1140             


Pro Val  Lys Ser Ser Pro Thr  Thr Ser Val Pro Ala  Val Ser Ser 
    1145                 1150                 1155             


Pro Pro  Met Gly Asn Gln Ser  Gly Gln Ser Val Pro  
    1160                 1165                 1170 


<210>  4057
<211>  460
<212>  PRT
<213>  homo sapiens

<400>  4057

Met Phe Leu Ala Thr Leu Tyr Phe Ala Leu Pro Leu Leu Asp Leu Leu 
1               5                   10                  15      


Leu Ser Ala Glu Val Ser Gly Gly Asp Arg Leu Asp Cys Val Lys Ala 
            20                  25                  30          


Ser Asp Gln Cys Leu Lys Glu Gln Ser Cys Ser Thr Lys Tyr Arg Thr 
        35                  40                  45              


Leu Arg Gln Cys Val Ala Gly Lys Glu Thr Asn Phe Ser Leu Ala Ser 
    50                  55                  60                  


Gly Leu Glu Ala Lys Asp Glu Cys Arg Ser Ala Met Glu Ala Leu Lys 
65                  70                  75                  80  


Gln Lys Ser Leu Tyr Asn Cys Arg Cys Lys Arg Gly Met Lys Lys Glu 
                85                  90                  95      


Lys Asn Cys Leu Arg Ile Tyr Trp Ser Met Tyr Gln Ser Leu Gln Gly 
            100                 105                 110         


Asn Asp Leu Leu Glu Asp Ser Pro Tyr Glu Pro Val Asn Ser Arg Leu 
        115                 120                 125             


Ser Asp Ile Phe Arg Val Val Pro Phe Ile Ser Val Glu His Ile Pro 
    130                 135                 140                 


Lys Gly Asn Asn Cys Leu Asp Ala Ala Lys Ala Cys Asn Leu Asp Asp 
145                 150                 155                 160 


Ile Cys Lys Lys Tyr Arg Ser Ala Tyr Ile Thr Pro Cys Thr Thr Ser 
                165                 170                 175     


Val Ser Asn Asp Val Cys Asn Arg Arg Lys Cys His Lys Ala Leu Arg 
            180                 185                 190         


Gln Phe Phe Asp Lys Val Pro Ala Lys His Ser Tyr Gly Met Leu Phe 
        195                 200                 205             


Cys Ser Cys Arg Asp Ile Ala Cys Thr Glu Arg Arg Arg Gln Thr Ile 
    210                 215                 220                 


Val Pro Val Cys Ser Tyr Glu Glu Arg Glu Lys Pro Asn Cys Leu Asn 
225                 230                 235                 240 


Leu Gln Asp Ser Cys Lys Thr Asn Tyr Ile Cys Arg Ser Arg Leu Ala 
                245                 250                 255     


Asp Phe Phe Thr Asn Cys Gln Pro Glu Ser Arg Ser Val Ser Ser Cys 
            260                 265                 270         


Leu Lys Glu Asn Tyr Ala Asp Cys Leu Leu Ala Tyr Ser Gly Leu Ile 
        275                 280                 285             


Gly Thr Val Met Thr Pro Asn Tyr Ile Asp Ser Ser Ser Leu Ser Val 
    290                 295                 300                 


Ala Pro Trp Cys Asp Cys Ser Asn Ser Gly Asn Asp Leu Glu Glu Cys 
305                 310                 315                 320 


Leu Lys Phe Leu Asn Phe Phe Lys Asp Asn Thr Cys Leu Lys Asn Ala 
                325                 330                 335     


Ile Gln Ala Phe Gly Asn Gly Ser Asp Val Thr Val Trp Gln Pro Ala 
            340                 345                 350         


Phe Pro Val Gln Thr Thr Thr Ala Thr Thr Thr Thr Ala Leu Arg Val 
        355                 360                 365             


Lys Asn Lys Pro Leu Gly Pro Ala Gly Ser Glu Asn Glu Ile Pro Thr 
    370                 375                 380                 


His Val Leu Pro Pro Cys Ala Asn Leu Gln Ala Gln Lys Leu Lys Ser 
385                 390                 395                 400 


Asn Val Ser Gly Asn Thr His Leu Cys Ile Ser Asn Gly Asn Tyr Glu 
                405                 410                 415     


Lys Glu Gly Leu Gly Ala Ser Ser His Ile Thr Thr Lys Ser Met Ala 
            420                 425                 430         


Ala Pro Pro Ser Cys Gly Leu Ser Pro Leu Leu Val Leu Val Val Thr 
        435                 440                 445             


Ala Leu Ser Thr Leu Leu Ser Leu Thr Glu Thr Ser 
    450                 455                 460 


<210>  4058
<211>  318
<212>  PRT
<213>  homo sapiens

<400>  4058

Met Ala Ser Pro Gly Cys Leu Leu Cys Val Leu Gly Leu Leu Leu Cys 
1               5                   10                  15      


Gly Ala Ala Ser Leu Glu Leu Ser Arg Pro His Gly Asp Thr Ala Lys 
            20                  25                  30          


Lys Pro Ile Ile Gly Ile Leu Met Gln Lys Cys Arg Asn Lys Val Met 
        35                  40                  45              


Lys Asn Tyr Gly Arg Tyr Tyr Ile Ala Ala Ser Tyr Val Lys Tyr Leu 
    50                  55                  60                  


Glu Ser Ala Gly Ala Arg Val Val Pro Val Arg Leu Asp Leu Thr Glu 
65                  70                  75                  80  


Lys Asp Tyr Glu Ile Leu Phe Lys Ser Ile Asn Gly Ile Leu Phe Pro 
                85                  90                  95      


Gly Gly Ser Val Asp Leu Arg Arg Ser Asp Tyr Ala Lys Val Ala Lys 
            100                 105                 110         


Ile Phe Tyr Asn Leu Ser Ile Gln Ser Phe Asp Asp Gly Asp Tyr Phe 
        115                 120                 125             


Pro Val Trp Gly Thr Cys Leu Gly Phe Glu Glu Leu Ser Leu Leu Ile 
    130                 135                 140                 


Ser Gly Glu Cys Leu Leu Thr Ala Thr Asp Thr Val Asp Val Ala Met 
145                 150                 155                 160 


Pro Leu Asn Phe Thr Gly Gly Gln Leu His Ser Arg Met Phe Gln Asn 
                165                 170                 175     


Phe Pro Thr Glu Leu Leu Leu Ser Leu Ala Val Glu Pro Leu Thr Ala 
            180                 185                 190         


Asn Phe His Lys Trp Ser Leu Ser Val Lys Asn Phe Thr Met Asn Glu 
        195                 200                 205             


Lys Leu Lys Lys Phe Phe Asn Val Leu Thr Thr Asn Thr Asp Gly Lys 
    210                 215                 220                 


Ile Glu Phe Ile Ser Thr Met Glu Gly Tyr Lys Tyr Pro Val Tyr Gly 
225                 230                 235                 240 


Val Gln Trp His Pro Glu Lys Ala Pro Tyr Glu Trp Lys Asn Leu Asp 
                245                 250                 255     


Gly Ile Ser His Ala Pro Asn Ala Val Lys Thr Ala Phe Tyr Leu Ala 
            260                 265                 270         


Glu Phe Phe Val Asn Glu Ala Arg Lys Asn Asn His His Phe Lys Ser 
        275                 280                 285             


Glu Ser Glu Glu Glu Lys Ala Leu Ile Tyr Gln Phe Ser Pro Ile Tyr 
    290                 295                 300                 


Thr Gly Asn Ile Ser Ser Phe Gln Gln Cys Tyr Ile Phe Asp 
305                 310                 315             


<210>  4059
<211>  106
<212>  PRT
<213>  homo sapiens

<400>  4059

Met Ser Ala Arg Gly Glu Gly Ala Gly Gln Pro Ser Thr Ser Ala Gln 
1               5                   10                  15      


Gly Gln Pro Ala Ala Pro Ala Pro Gln Lys Arg Gly Arg Gly Arg Pro 
            20                  25                  30          


Arg Lys Gln Gln Gln Glu Pro Thr Gly Glu Pro Ser Pro Lys Arg Pro 
        35                  40                  45              


Arg Gly Arg Pro Lys Gly Ser Lys Asn Lys Ser Pro Ser Lys Ala Ala 
    50                  55                  60                  


Gln Lys Lys Ala Glu Ala Thr Gly Glu Lys Arg Pro Arg Gly Arg Pro 
65                  70                  75                  80  


Arg Lys Trp Asp Asn Leu Leu Pro Arg Thr Ser Ser Lys Lys Lys Thr 
                85                  90                  95      


Ser Leu Gly Asn Ser Thr Lys Arg Ser His 
            100                 105     


<210>  4060
<211>  554
<212>  PRT
<213>  homo sapiens

<400>  4060

Met Asn Val Leu Leu Phe Trp Lys Thr Phe Leu Leu Tyr Asn Gln Gly 
1               5                   10                  15      


Pro Glu Tyr His Tyr Leu His Gln Met Leu Gly Leu Gly Leu Cys Leu 
            20                  25                  30          


Ser Arg Ala Ser Ala Ser Val Leu Asn Leu Asn Cys Ser Leu Ile Leu 
        35                  40                  45              


Leu Pro Met Cys Arg Thr Leu Leu Ala Tyr Leu Arg Gly Ser Gln Lys 
    50                  55                  60                  


Val Pro Ser Arg Arg Thr Arg Arg Leu Leu Asp Lys Ser Arg Thr Phe 
65                  70                  75                  80  


His Ile Thr Cys Gly Val Thr Ile Cys Ile Phe Ser Gly Val His Val 
                85                  90                  95      


Ala Ala His Leu Val Asn Ala Leu Asn Phe Ser Val Asn Tyr Ser Glu 
            100                 105                 110         


Asp Phe Val Glu Leu Asn Ala Ala Arg Tyr Arg Asp Glu Asp Pro Arg 
        115                 120                 125             


Lys Leu Leu Phe Thr Thr Val Pro Gly Leu Thr Gly Val Cys Met Val 
    130                 135                 140                 


Val Val Leu Phe Leu Met Ile Thr Ala Ser Thr Tyr Ala Ile Arg Val 
145                 150                 155                 160 


Ser Asn Tyr Asp Ile Phe Trp Tyr Thr His Asn Leu Phe Phe Val Phe 
                165                 170                 175     


Tyr Met Leu Leu Thr Leu His Val Ser Gly Gly Leu Leu Lys Tyr Gln 
            180                 185                 190         


Thr Asn Leu Asp Thr His Pro Pro Gly Cys Ile Ser Leu Asn Arg Thr 
        195                 200                 205             


Ser Ser Gln Asn Ile Ser Leu Pro Glu Tyr Phe Ser Glu His Phe His 
    210                 215                 220                 


Glu Pro Phe Pro Glu Gly Phe Ser Lys Pro Ala Glu Phe Thr Gln His 
225                 230                 235                 240 


Lys Phe Val Lys Ile Cys Met Glu Glu Pro Arg Phe Gln Ala Asn Phe 
                245                 250                 255     


Pro Gln Thr Trp Leu Trp Ile Ser Gly Pro Leu Cys Leu Tyr Cys Ala 
            260                 265                 270         


Glu Arg Leu Tyr Arg Tyr Ile Arg Ser Asn Lys Pro Val Thr Ile Ile 
        275                 280                 285             


Ser Val Ile Ser His Pro Ser Asp Val Met Glu Ile Arg Met Val Lys 
    290                 295                 300                 


Glu Asn Phe Lys Ala Arg Pro Gly Gln Tyr Ile Thr Leu His Cys Pro 
305                 310                 315                 320 


Ser Val Ser Ala Leu Glu Asn His Pro Phe Thr Leu Thr Met Cys Pro 
                325                 330                 335     


Thr Glu Thr Lys Ala Thr Phe Gly Val His Leu Lys Ile Val Gly Asp 
            340                 345                 350         


Trp Thr Glu Arg Phe Arg Asp Leu Leu Leu Pro Pro Ser Ser Gln Asp 
        355                 360                 365             


Ser Glu Ile Leu Pro Phe Ile Gln Ser Arg Asn Tyr Pro Lys Leu Tyr 
    370                 375                 380                 


Ile Asp Gly Pro Phe Gly Ser Pro Phe Glu Glu Ser Leu Asn Tyr Glu 
385                 390                 395                 400 


Val Ser Leu Cys Val Ala Gly Gly Ile Gly Val Thr Pro Phe Ala Ser 
                405                 410                 415     


Ile Leu Asn Thr Leu Leu Asp Asp Trp Lys Pro Tyr Lys Leu Arg Arg 
            420                 425                 430         


Leu Tyr Phe Ile Trp Val Cys Arg Asp Ile Gln Ser Phe Arg Trp Phe 
        435                 440                 445             


Ala Asp Leu Leu Cys Met Leu His Asn Lys Phe Trp Gln Glu Asn Arg 
    450                 455                 460                 


Pro Asp Tyr Val Asn Ile Gln Leu Tyr Leu Ser Gln Thr Asp Gly Ile 
465                 470                 475                 480 


Gln Lys Ile Ile Gly Glu Lys Tyr His Ala Leu Asn Ser Arg Leu Phe 
                485                 490                 495     


Ile Gly Arg Pro Arg Trp Lys Leu Leu Phe Asp Glu Ile Ala Lys Tyr 
            500                 505                 510         


Asn Arg Gly Lys Thr Val Gly Val Phe Cys Cys Gly Pro Asn Ser Leu 
        515                 520                 525             


Ser Lys Thr Leu His Lys Leu Ser Asn Gln Asn Asn Ser Tyr Gly Thr 
    530                 535                 540                 


Arg Phe Glu Tyr Asn Lys Glu Ser Phe Ser 
545                 550                 


<210>  4061
<211>  231
<212>  PRT
<213>  homo sapiens

<400>  4061

Met Ala Gly Lys Lys Val Leu Ile Val Tyr Ala His Gln Glu Pro Lys 
1               5                   10                  15      


Ser Phe Asn Gly Ser Leu Lys Asn Val Ala Val Asp Glu Leu Ser Arg 
            20                  25                  30          


Gln Gly Cys Thr Val Thr Val Ser Asp Leu Tyr Ala Met Asn Leu Glu 
        35                  40                  45              


Pro Arg Ala Thr Asp Lys Asp Ile Thr Gly Thr Leu Ser Asn Pro Glu 
    50                  55                  60                  


Val Phe Asn Tyr Gly Val Glu Thr His Glu Ala Tyr Lys Gln Arg Ser 
65                  70                  75                  80  


Leu Ala Ser Asp Ile Thr Asp Glu Gln Lys Lys Val Arg Glu Ala Asp 
                85                  90                  95      


Leu Val Ile Phe Gln Phe Pro Leu Tyr Trp Phe Ser Val Pro Ala Ile 
            100                 105                 110         


Leu Lys Gly Trp Met Asp Arg Val Leu Cys Gln Gly Phe Ala Phe Asp 
        115                 120                 125             


Ile Pro Gly Phe Tyr Asp Ser Gly Leu Leu Gln Gly Lys Leu Ala Leu 
    130                 135                 140                 


Leu Ser Val Thr Thr Gly Gly Thr Ala Glu Met Tyr Thr Lys Thr Gly 
145                 150                 155                 160 


Val Asn Gly Asp Ser Arg Tyr Phe Leu Trp Pro Leu Gln His Gly Thr 
                165                 170                 175     


Leu His Phe Cys Gly Phe Lys Val Leu Ala Pro Gln Ile Ser Phe Ala 
            180                 185                 190         


Pro Glu Ile Ala Ser Glu Glu Glu Arg Lys Gly Met Val Ala Ala Trp 
        195                 200                 205             


Ser Gln Arg Leu Gln Thr Ile Trp Lys Glu Glu Pro Ile Pro Cys Thr 
    210                 215                 220                 


Ala His Trp His Phe Gly Gln 
225                 230     


<210>  4062
<211>  133
<212>  PRT
<213>  homo sapiens

<400>  4062

Met Arg Met Ser Leu Ala Gln Arg Val Leu Leu Thr Trp Leu Phe Thr 
1               5                   10                  15      


Leu Leu Phe Leu Ile Met Leu Val Leu Lys Leu Asp Glu Lys Ala Pro 
            20                  25                  30          


Trp Asn Trp Phe Leu Ile Phe Ile Pro Val Trp Ile Phe Asp Thr Ile 
        35                  40                  45              


Leu Leu Val Leu Leu Ile Val Lys Met Ala Gly Arg Cys Lys Ser Gly 
    50                  55                  60                  


Phe Asp Pro Arg His Gly Ser His Asn Ile Lys Lys Lys Ala Trp Tyr 
65                  70                  75                  80  


Leu Ile Ala Met Leu Leu Lys Leu Ala Phe Cys Leu Ala Leu Cys Ala 
                85                  90                  95      


Lys Leu Glu Gln Phe Thr Thr Met Asn Leu Ser Tyr Val Phe Ile Pro 
            100                 105                 110         


Leu Trp Ala Leu Leu Ala Gly Ala Leu Thr Glu Leu Gly Tyr Asn Val 
        115                 120                 125             


Phe Phe Val Arg Asp 
    130             


<210>  4063
<211>  351
<212>  PRT
<213>  homo sapiens

<400>  4063

Met Ala Leu Pro Phe Gln Lys Glu Leu Glu Lys Tyr Lys Asn Ile Asp 
1               5                   10                  15      


Glu Asp Glu Leu Leu Gly Lys Leu Ser Glu Glu Glu Leu Lys Gln Leu 
            20                  25                  30          


Glu Asn Val Leu Asp Asp Leu Asp Pro Glu Ser Ala Met Leu Pro Ala 
        35                  40                  45              


Gly Phe Arg Gln Lys Asp Gln Thr Gln Lys Ala Ala Thr Gly Pro Phe 
    50                  55                  60                  


Asp Arg Glu His Leu Leu Met Tyr Leu Glu Lys Glu Ala Leu Glu Gln 
65                  70                  75                  80  


Lys Asp Arg Glu Asp Phe Val Pro Phe Thr Gly Glu Lys Lys Gly Arg 
                85                  90                  95      


Val Phe Ile Pro Lys Glu Lys Pro Ile Glu Thr Arg Lys Glu Glu Lys 
            100                 105                 110         


Val Thr Leu Asp Pro Glu Leu Glu Glu Ala Leu Ala Ser Ala Ser Asp 
        115                 120                 125             


Thr Glu Leu Tyr Asp Leu Ala Ala Val Leu Gly Val His Asn Leu Leu 
    130                 135                 140                 


Asn Asn Pro Lys Phe Asp Glu Glu Thr Ala Asn Asn Lys Gly Gly Lys 
145                 150                 155                 160 


Gly Pro Val Arg Asn Val Val Lys Gly Glu Lys Val Lys Pro Val Phe 
                165                 170                 175     


Glu Glu Pro Pro Asn Pro Thr Asn Val Glu Ile Ser Leu Gln Gln Met 
            180                 185                 190         


Lys Ala Asn Asp Pro Ser Leu Gln Glu Val Asn Leu Asn Asn Ile Lys 
        195                 200                 205             


Asn Ile Pro Ile Pro Thr Leu Arg Glu Phe Ala Lys Ala Leu Glu Thr 
    210                 215                 220                 


Asn Thr His Val Lys Lys Phe Ser Leu Ala Ala Thr Arg Ser Asn Asp 
225                 230                 235                 240 


Pro Val Ala Ile Ala Phe Ala Asp Met Leu Lys Val Asn Lys Thr Leu 
                245                 250                 255     


Thr Ser Leu Asn Ile Glu Ser Asn Phe Ile Thr Gly Thr Gly Ile Leu 
            260                 265                 270         


Ala Leu Val Glu Ala Leu Lys Glu Asn Asp Thr Leu Thr Glu Ile Lys 
        275                 280                 285             


Ile Asp Asn Gln Arg Gln Gln Leu Gly Thr Ala Val Glu Met Glu Ile 
    290                 295                 300                 


Ala Gln Met Leu Glu Glu Asn Ser Arg Ile Leu Lys Phe Gly Tyr Gln 
305                 310                 315                 320 


Phe Thr Lys Gln Gly Pro Arg Thr Arg Val Ala Ala Ala Ile Thr Lys 
                325                 330                 335     


Asn Asn Asp Leu Val Arg Lys Lys Arg Val Glu Ala Asp Arg Arg 
            340                 345                 350     


<210>  4064
<211>  520
<212>  PRT
<213>  homo sapiens

<400>  4064

Met Pro Gly Ser Leu Pro Leu Asn Ala Glu Ala Cys Trp Pro Lys Asp 
1               5                   10                  15      


Val Gly Ile Val Ala Leu Glu Ile Tyr Phe Pro Ser Gln Tyr Val Asp 
            20                  25                  30          


Gln Ala Glu Leu Glu Lys Tyr Asp Gly Val Asp Ala Gly Lys Tyr Thr 
        35                  40                  45              


Ile Gly Leu Gly Gln Ala Lys Met Gly Phe Cys Thr Asp Arg Glu Asp 
    50                  55                  60                  


Ile Asn Ser Leu Cys Met Thr Val Val Gln Asn Leu Met Glu Arg Asn 
65                  70                  75                  80  


Asn Leu Ser Tyr Asp Cys Ile Gly Arg Leu Glu Val Gly Thr Glu Thr 
                85                  90                  95      


Ile Ile Asp Lys Ser Lys Ser Val Lys Thr Asn Leu Met Gln Leu Phe 
            100                 105                 110         


Glu Glu Ser Gly Asn Thr Asp Ile Glu Gly Ile Asp Thr Thr Asn Ala 
        115                 120                 125             


Cys Tyr Gly Gly Thr Ala Ala Val Phe Asn Ala Val Asn Trp Ile Glu 
    130                 135                 140                 


Ser Ser Ser Trp Asp Gly Arg Tyr Ala Leu Val Val Ala Gly Asp Ile 
145                 150                 155                 160 


Ala Val Tyr Ala Thr Gly Asn Ala Arg Pro Thr Gly Gly Val Gly Ala 
                165                 170                 175     


Val Ala Leu Leu Ile Gly Pro Asn Ala Pro Leu Ile Phe Glu Arg Gly 
            180                 185                 190         


Leu Arg Gly Thr His Met Gln His Ala Tyr Asp Phe Tyr Lys Pro Asp 
        195                 200                 205             


Met Leu Ser Glu Tyr Pro Ile Val Asp Gly Lys Leu Ser Ile Gln Cys 
    210                 215                 220                 


Tyr Leu Ser Ala Leu Asp Arg Cys Tyr Ser Val Tyr Cys Lys Lys Ile 
225                 230                 235                 240 


His Ala Gln Trp Gln Lys Glu Gly Asn Asp Lys Asp Phe Thr Leu Asn 
                245                 250                 255     


Asp Phe Gly Phe Met Ile Phe His Ser Pro Tyr Cys Lys Leu Val Gln 
            260                 265                 270         


Lys Ser Leu Ala Arg Met Leu Leu Asn Asp Phe Leu Asn Asp Gln Asn 
        275                 280                 285             


Arg Asp Lys Asn Ser Ile Tyr Ser Gly Leu Glu Ala Phe Gly Asp Val 
    290                 295                 300                 


Lys Leu Glu Asp Thr Tyr Phe Asp Arg Asp Val Glu Lys Ala Phe Met 
305                 310                 315                 320 


Lys Ala Ser Ser Glu Leu Phe Ser Gln Lys Thr Lys Ala Ser Leu Leu 
                325                 330                 335     


Val Ser Asn Gln Asn Gly Asn Met Tyr Thr Ser Ser Val Tyr Gly Ser 
            340                 345                 350         


Leu Ala Ser Val Leu Ala Gln Tyr Ser Pro Gln Gln Leu Ala Gly Lys 
        355                 360                 365             


Arg Ile Gly Val Phe Ser Tyr Gly Ser Gly Leu Ala Ala Thr Leu Tyr 
    370                 375                 380                 


Ser Leu Lys Val Thr Gln Asp Ala Thr Pro Gly Ser Ala Leu Asp Lys 
385                 390                 395                 400 


Ile Thr Ala Ser Leu Cys Asp Leu Lys Ser Arg Leu Asp Ser Arg Thr 
                405                 410                 415     


Gly Val Ala Pro Asp Val Phe Ala Glu Asn Met Lys Leu Arg Glu Asp 
            420                 425                 430         


Thr His His Leu Val Asn Tyr Ile Pro Gln Gly Ser Ile Asp Ser Leu 
        435                 440                 445             


Phe Glu Gly Thr Trp Tyr Leu Val Arg Val Asp Glu Lys His Arg Arg 
    450                 455                 460                 


Thr Tyr Ala Arg Arg Pro Thr Pro Asn Asp Asp Thr Leu Asp Glu Gly 
465                 470                 475                 480 


Val Gly Leu Val His Ser Asn Ile Ala Thr Glu His Ile Pro Ser Pro 
                485                 490                 495     


Ala Lys Lys Val Pro Arg Leu Pro Ala Thr Ala Ala Glu Pro Glu Ala 
            500                 505                 510         


Ala Val Ile Ser Asn Gly Glu His 
        515                 520 


<210>  4065
<211>  180
<212>  PRT
<213>  homo sapiens

<400>  4065

Met Ala Ser Thr Ser Tyr Asp Tyr Cys Arg Val Pro Met Glu Asp Gly 
1               5                   10                  15      


Asp Lys Arg Cys Lys Leu Leu Leu Gly Ile Gly Ile Leu Val Leu Leu 
            20                  25                  30          


Ile Ile Val Ile Leu Gly Val Pro Leu Ile Ile Phe Thr Ile Lys Ala 
        35                  40                  45              


Asn Ser Glu Ala Cys Arg Asp Gly Leu Arg Ala Val Met Glu Cys Arg 
    50                  55                  60                  


Asn Val Thr His Leu Leu Gln Gln Glu Leu Thr Glu Ala Gln Lys Gly 
65                  70                  75                  80  


Phe Gln Asp Val Glu Ala Gln Ala Ala Thr Cys Asn His Thr Val Met 
                85                  90                  95      


Ala Leu Met Ala Ser Leu Asp Ala Glu Lys Ala Gln Gly Gln Lys Lys 
            100                 105                 110         


Val Glu Glu Leu Glu Gly Glu Ile Thr Thr Leu Asn His Lys Leu Gln 
        115                 120                 125             


Asp Ala Ser Ala Glu Val Glu Arg Leu Arg Arg Glu Asn Gln Val Leu 
    130                 135                 140                 


Ser Val Arg Ile Ala Asp Lys Lys Tyr Tyr Pro Ser Ser Gln Asp Ser 
145                 150                 155                 160 


Ser Ser Ala Ala Ala Pro Gln Leu Leu Ile Val Leu Leu Gly Leu Ser 
                165                 170                 175     


Ala Leu Leu Gln 
            180 


<210>  4066
<211>  334
<212>  PRT
<213>  homo sapiens

<400>  4066

Met Thr Glu Asn Ser Asp Lys Val Pro Ile Ala Leu Val Gly Pro Asp 
1               5                   10                  15      


Asp Val Glu Phe Cys Ser Pro Pro Ala Tyr Ala Thr Leu Thr Val Lys 
            20                  25                  30          


Pro Ser Ser Pro Ala Arg Leu Leu Lys Val Gly Ala Val Val Leu Ile 
        35                  40                  45              


Ser Gly Ala Val Leu Leu Leu Phe Gly Ala Ile Gly Ala Phe Tyr Phe 
    50                  55                  60                  


Trp Lys Gly Ser Asp Ser His Ile Tyr Asn Val His Tyr Thr Met Ser 
65                  70                  75                  80  


Ile Asn Gly Lys Leu Gln Asp Gly Ser Met Glu Ile Asp Ala Gly Asn 
                85                  90                  95      


Asn Leu Glu Thr Phe Lys Met Gly Ser Gly Ala Glu Glu Ala Ile Ala 
            100                 105                 110         


Val Asn Asp Phe Gln Asn Gly Ile Thr Gly Ile Arg Phe Ala Gly Gly 
        115                 120                 125             


Glu Lys Cys Tyr Ile Lys Ala Gln Val Lys Ala Arg Ile Pro Glu Val 
    130                 135                 140                 


Gly Ala Val Thr Lys Gln Ser Ile Ser Ser Lys Leu Glu Gly Lys Ile 
145                 150                 155                 160 


Met Pro Val Lys Tyr Glu Glu Asn Ser Leu Ile Trp Val Ala Val Asp 
                165                 170                 175     


Gln Pro Val Lys Asp Asn Ser Phe Leu Ser Ser Lys Val Leu Glu Leu 
            180                 185                 190         


Cys Gly Asp Leu Pro Ile Phe Trp Leu Lys Pro Thr Tyr Pro Lys Glu 
        195                 200                 205             


Ile Gln Arg Glu Arg Arg Glu Val Val Arg Lys Ile Val Pro Thr Thr 
    210                 215                 220                 


Thr Lys Arg Pro His Ser Gly Pro Arg Ser Asn Pro Gly Ala Gly Arg 
225                 230                 235                 240 


Leu Asn Asn Glu Thr Arg Pro Ser Val Gln Glu Asp Ser Gln Ala Phe 
                245                 250                 255     


Asn Pro Asp Asn Pro Tyr His Gln Gln Glu Gly Glu Ser Met Thr Phe 
            260                 265                 270         


Asp Pro Arg Leu Asp His Glu Gly Ile Cys Cys Ile Glu Cys Arg Arg 
        275                 280                 285             


Ser Tyr Thr His Cys Gln Lys Ile Cys Glu Pro Leu Gly Gly Tyr Tyr 
    290                 295                 300                 


Pro Trp Pro Tyr Asn Tyr Gln Gly Cys Arg Ser Ala Cys Arg Val Ile 
305                 310                 315                 320 


Met Pro Cys Ser Trp Trp Val Ala Arg Ile Leu Gly Met Val 
                325                 330                 


<210>  4067
<211>  682
<212>  PRT
<213>  homo sapiens

<400>  4067

Met Asn Pro Gln Gln Gln Arg Met Ala Ala Ile Gly Thr Asp Lys Glu 
1               5                   10                  15      


Leu Ser Asp Leu Leu Asp Phe Ser Ala Met Phe Ser Pro Pro Val Asn 
            20                  25                  30          


Ser Gly Lys Thr Arg Pro Thr Thr Leu Gly Ser Ser Gln Phe Ser Gly 
        35                  40                  45              


Ser Gly Ile Asp Glu Arg Gly Gly Thr Thr Ser Trp Gly Thr Ser Gly 
    50                  55                  60                  


Gln Pro Ser Pro Ser Tyr Asp Ser Ser Arg Gly Phe Thr Asp Ser Pro 
65                  70                  75                  80  


His Tyr Ser Asp His Leu Asn Asp Ser Arg Leu Gly Ala His Glu Gly 
                85                  90                  95      


Leu Ser Pro Thr Pro Phe Met Asn Ser Asn Leu Met Gly Lys Thr Ser 
            100                 105                 110         


Glu Arg Gly Ser Phe Ser Leu Tyr Ser Arg Asp Thr Gly Leu Pro Gly 
        115                 120                 125             


Cys Gln Ser Ser Leu Leu Arg Gln Asp Leu Gly Leu Gly Ser Pro Ala 
    130                 135                 140                 


Gln Leu Ser Ser Ser Gly Lys Pro Gly Thr Ala Tyr Tyr Ser Phe Ser 
145                 150                 155                 160 


Ala Thr Ser Ser Arg Arg Arg Pro Leu His Asp Ser Ala Ala Leu Asp 
                165                 170                 175     


Pro Leu Gln Ala Lys Lys Val Arg Lys Val Pro Pro Gly Leu Pro Ser 
            180                 185                 190         


Ser Val Tyr Ala Pro Ser Pro Asn Ser Asp Asp Phe Asn Arg Glu Ser 
        195                 200                 205             


Pro Ser Tyr Pro Ser Pro Lys Pro Pro Thr Ser Met Phe Ala Ser Thr 
    210                 215                 220                 


Phe Phe Met Gln Asp Gly Thr His Asn Ser Ser Asp Leu Trp Ser Ser 
225                 230                 235                 240 


Ser Asn Gly Met Ser Gln Pro Gly Phe Gly Gly Ile Leu Gly Thr Ser 
                245                 250                 255     


Thr Ser His Met Ser Gln Ser Ser Ser Tyr Gly Asn Leu His Ser His 
            260                 265                 270         


Asp Arg Leu Ser Tyr Pro Pro His Ser Val Ser Pro Thr Asp Ile Asn 
        275                 280                 285             


Thr Ser Leu Pro Pro Met Ser Ser Phe His Arg Gly Ser Thr Ser Ser 
    290                 295                 300                 


Ser Pro Tyr Val Ala Ala Ser His Thr Pro Pro Ile Asn Gly Ser Asp 
305                 310                 315                 320 


Ser Ile Leu Gly Thr Arg Gly Asn Ala Ala Gly Ser Ser Gln Thr Gly 
                325                 330                 335     


Asp Ala Leu Gly Lys Ala Leu Ala Ser Ile Tyr Ser Pro Asp His Thr 
            340                 345                 350         


Ser Ser Ser Phe Pro Ser Asn Pro Ser Thr Pro Val Gly Ser Pro Ser 
        355                 360                 365             


Pro Leu Thr Gly Thr Ser Gln Trp Pro Arg Pro Gly Gly Gln Ala Pro 
    370                 375                 380                 


Ser Ser Pro Ser Tyr Glu Asn Ser Leu His Ser Leu Gln Ser Arg Met 
385                 390                 395                 400 


Glu Asp Arg Leu Asp Arg Leu Asp Asp Ala Ile His Val Leu Arg Asn 
                405                 410                 415     


His Ala Val Gly Pro Ser Thr Ser Leu Pro Ala Gly His Ser Asp Ile 
            420                 425                 430         


His Ser Leu Leu Gly Pro Ser His Asn Ala Pro Ile Gly Ser Leu Asn 
        435                 440                 445             


Ser Asn Tyr Gly Gly Ser Ser Leu Val Ala Ser Ser Arg Ser Ala Ser 
    450                 455                 460                 


Met Val Gly Thr His Arg Glu Asp Ser Val Ser Leu Asn Gly Asn His 
465                 470                 475                 480 


Ser Val Leu Ser Ser Thr Val Thr Thr Ser Ser Thr Asp Leu Asn His 
                485                 490                 495     


Lys Thr Gln Glu Asn Tyr Arg Gly Gly Leu Gln Ser Gln Ser Gly Thr 
            500                 505                 510         


Val Val Thr Thr Glu Ile Lys Thr Glu Asn Lys Glu Lys Asp Glu Asn 
        515                 520                 525             


Leu His Glu Pro Pro Ser Ser Asp Asp Met Lys Ser Asp Asp Glu Ser 
    530                 535                 540                 


Ser Gln Lys Asp Ile Lys Val Ser Ser Arg Gly Arg Thr Ser Ser Thr 
545                 550                 555                 560 


Asn Glu Asp Glu Asp Leu Asn Pro Glu Gln Lys Ile Glu Arg Glu Lys 
                565                 570                 575     


Glu Arg Arg Met Ala Asn Asn Ala Arg Glu Arg Leu Arg Val Arg Asp 
            580                 585                 590         


Ile Asn Glu Ala Phe Lys Glu Leu Gly Arg Met Cys Gln Leu His Leu 
        595                 600                 605             


Lys Ser Glu Lys Pro Gln Thr Lys Leu Leu Ile Leu His Gln Ala Val 
    610                 615                 620                 


Ala Val Ile Leu Ser Leu Glu Gln Gln Val Arg Glu Arg Asn Leu Asn 
625                 630                 635                 640 


Pro Lys Ala Ala Cys Leu Lys Arg Arg Glu Glu Glu Lys Val Ser Ala 
                645                 650                 655     


Val Ser Ala Glu Pro Pro Thr Thr Leu Pro Gly Thr His Pro Gly Leu 
            660                 665                 670         


Ser Glu Thr Thr Asn Pro Met Gly His Met 
        675                 680         


<210>  4068
<211>  412
<212>  PRT
<213>  homo sapiens

<400>  4068

Met Thr Asp Leu Tyr Tyr Leu Ser Gln Thr Asp Gly Ala Gly Asp Trp 
1               5                   10                  15      


Arg Glu Lys Glu Ala Lys Asp Leu Thr Glu Leu Val Gln Arg Arg Ile 
            20                  25                  30          


Thr Tyr Leu Gln Asn Pro Lys Asp Cys Ser Lys Ala Lys Lys Leu Val 
        35                  40                  45              


Cys Asn Ile Asn Lys Gly Cys Gly Tyr Gly Cys Gln Leu His His Val 
    50                  55                  60                  


Val Tyr Cys Phe Met Ile Ala Tyr Gly Thr Gln Arg Thr Leu Ile Leu 
65                  70                  75                  80  


Glu Ser Gln Asn Trp Arg Tyr Ala Thr Gly Gly Trp Glu Thr Val Phe 
                85                  90                  95      


Arg Pro Val Ser Glu Thr Cys Thr Asp Arg Ser Gly Ile Ser Thr Gly 
            100                 105                 110         


His Trp Ser Gly Glu Val Lys Asp Lys Asn Val Gln Val Val Glu Leu 
        115                 120                 125             


Pro Ile Val Asp Ser Leu His Pro Arg Pro Pro Tyr Leu Pro Leu Ala 
    130                 135                 140                 


Val Pro Glu Asp Leu Ala Asp Arg Leu Val Arg Val His Gly Asp Pro 
145                 150                 155                 160 


Ala Val Trp Trp Val Ser Gln Phe Val Lys Tyr Leu Ile Arg Pro Gln 
                165                 170                 175     


Pro Trp Leu Glu Lys Glu Ile Glu Glu Ala Thr Lys Lys Leu Gly Phe 
            180                 185                 190         


Lys His Pro Val Ile Gly Val His Val Arg Arg Thr Asp Lys Val Gly 
        195                 200                 205             


Thr Glu Ala Ala Phe His Pro Ile Glu Glu Tyr Met Val His Val Glu 
    210                 215                 220                 


Glu His Phe Gln Leu Leu Ala Arg Arg Met Gln Val Asp Lys Lys Arg 
225                 230                 235                 240 


Val Tyr Leu Ala Thr Asp Asp Pro Ser Leu Leu Lys Glu Ala Lys Thr 
                245                 250                 255     


Lys Tyr Pro Asn Tyr Glu Phe Ile Ser Asp Asn Ser Ile Ser Trp Ser 
            260                 265                 270         


Ala Gly Leu His Asn Arg Tyr Thr Glu Asn Ser Leu Arg Gly Val Ile 
        275                 280                 285             


Leu Asp Ile His Phe Leu Ser Gln Ala Asp Phe Leu Val Cys Thr Phe 
    290                 295                 300                 


Ser Ser Gln Val Cys Arg Val Ala Tyr Glu Ile Met Gln Thr Leu His 
305                 310                 315                 320 


Pro Asp Ala Ser Ala Asn Phe His Ser Leu Asp Asp Ile Tyr Tyr Phe 
                325                 330                 335     


Gly Gly Gln Asn Ala His Asn Gln Ile Ala Ile Tyr Ala His Gln Pro 
            340                 345                 350         


Arg Thr Ala Asp Glu Ile Pro Met Glu Pro Gly Asp Ile Ile Gly Val 
        355                 360                 365             


Ala Gly Asn His Trp Asp Gly Tyr Ser Lys Gly Val Asn Arg Lys Leu 
    370                 375                 380                 


Gly Arg Thr Gly Leu Tyr Pro Ser Tyr Lys Val Arg Glu Lys Ile Glu 
385                 390                 395                 400 


Thr Val Lys Tyr Pro Thr Tyr Pro Glu Ala Glu Lys 
                405                 410         


<210>  4069
<211>  570
<212>  PRT
<213>  homo sapiens

<400>  4069

Met Ala Asn Pro Lys Glu Lys Thr Ala Met Cys Leu Val Asn Glu Leu 
1               5                   10                  15      


Ala Arg Phe Asn Arg Val Gln Pro Gln Tyr Lys Leu Leu Asn Glu Arg 
            20                  25                  30          


Gly Pro Ala His Ser Lys Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
        35                  40                  45              


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
    50                  55                  60                  


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
65                  70                  75                  80  


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
                85                  90                  95      


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
            100                 105                 110         


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
        115                 120                 125             


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
    130                 135                 140                 


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
145                 150                 155                 160 


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
                165                 170                 175     


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
            180                 185                 190         


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
        195                 200                 205             


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
    210                 215                 220                 


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
225                 230                 235                 240 


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
                245                 250                 255     


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
            260                 265                 270         


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
        275                 280                 285             


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
    290                 295                 300                 


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
305                 310                 315                 320 


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
                325                 330                 335     


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
            340                 345                 350         


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
        355                 360                 365             


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
    370                 375                 380                 


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
385                 390                 395                 400 


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
                405                 410                 415     


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
            420                 425                 430         


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
        435                 440                 445             


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
    450                 455                 460                 


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
465                 470                 475                 480 


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
                485                 490                 495     


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Ala Ala 
            500                 505                 510         


Leu Ser Ala Leu Lys Gln Phe Ser Glu Gln Gly Leu Asp Pro Ile Asp 
        515                 520                 525             


Gly Ala Met Asn Ile Glu Lys Gly Ser Leu Glu Lys Gln Ala Lys His 
    530                 535                 540                 


Leu Arg Glu Lys Ala Asp Asn Asn Gln Ala Pro Pro Gly Ser Ile Ala 
545                 550                 555                 560 


Gln Asp Cys Lys Lys Ser Asn Ser Ala Val 
                565                 570 


<210>  4070
<211>  538
<212>  PRT
<213>  homo sapiens

<400>  4070

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15      


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30          


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45              


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60                  


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80  


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95      


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
            100                 105                 110         


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
        115                 120                 125             


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
    130                 135                 140                 


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
145                 150                 155                 160 


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
                165                 170                 175     


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
            180                 185                 190         


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
        195                 200                 205             


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
    210                 215                 220                 


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
225                 230                 235                 240 


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
                245                 250                 255     


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
            260                 265                 270         


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
        275                 280                 285             


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
    290                 295                 300                 


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
305                 310                 315                 320 


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
                325                 330                 335     


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
            340                 345                 350         


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
        355                 360                 365             


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
    370                 375                 380                 


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
385                 390                 395                 400 


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
                405                 410                 415     


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
            420                 425                 430         


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
        435                 440                 445             


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
    450                 455                 460                 


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Ala Ala 
465                 470                 475                 480 


Leu Ser Ala Leu Lys Gln Phe Ser Glu Gln Gly Leu Asp Pro Ile Asp 
                485                 490                 495     


Gly Ala Met Asn Ile Glu Lys Gly Ser Leu Glu Lys Gln Ala Lys His 
            500                 505                 510         


Leu Arg Glu Lys Ala Asp Asn Asn Gln Ala Pro Pro Gly Ser Ile Ala 
        515                 520                 525             


Gln Asp Cys Lys Lys Ser Asn Ser Ala Val 
    530                 535             


<210>  4071
<211>  504
<212>  PRT
<213>  homo sapiens

<400>  4071

Met Lys Arg Gly Glu Pro Ala Ile Tyr Arg Pro Leu Asp Pro Lys Pro 
1               5                   10                  15      


Phe Pro Asn Tyr Arg Ala Asn Tyr Asn Phe Arg Gly Met Tyr Asn Gln 
            20                  25                  30          


Arg Tyr His Cys Pro Val Pro Lys Ile Phe Tyr Val Gln Leu Thr Val 
        35                  40                  45              


Gly Asn Asn Glu Phe Phe Gly Glu Gly Lys Thr Arg Gln Ala Ala Arg 
    50                  55                  60                  


His Asn Ala Ala Met Lys Ala Leu Gln Ala Leu Gln Asn Glu Pro Ile 
65                  70                  75                  80  


Pro Glu Arg Ser Pro Gln Asn Gly Glu Ser Gly Lys Asp Val Asp Asp 
                85                  90                  95      


Asp Lys Asp Ala Asn Lys Ser Glu Ile Ser Leu Val Phe Glu Ile Ala 
            100                 105                 110         


Leu Lys Arg Asn Met Pro Val Ser Phe Glu Val Ile Lys Glu Ser Gly 
        115                 120                 125             


Pro Pro His Met Lys Ser Phe Val Thr Arg Val Ser Val Gly Glu Phe 
    130                 135                 140                 


Ser Ala Glu Gly Glu Gly Asn Ser Lys Lys Leu Ser Lys Lys Arg Ala 
145                 150                 155                 160 


Ala Thr Thr Val Leu Gln Glu Leu Lys Lys Leu Pro Pro Leu Pro Val 
                165                 170                 175     


Val Glu Lys Pro Lys Leu Phe Phe Lys Lys Arg Pro Lys Thr Ile Val 
            180                 185                 190         


Lys Ala Gly Pro Glu Tyr Gly Gln Gly Met Asn Pro Ile Ser Arg Leu 
        195                 200                 205             


Ala Gln Ile Gln Gln Ala Lys Lys Glu Lys Glu Pro Asp Tyr Val Leu 
    210                 215                 220                 


Leu Ser Glu Arg Gly Met Pro Arg Arg Arg Glu Phe Val Met Gln Val 
225                 230                 235                 240 


Lys Val Gly Asn Glu Val Ala Thr Gly Thr Gly Pro Asn Lys Lys Ile 
                245                 250                 255     


Ala Lys Lys Asn Ala Ala Glu Ala Met Leu Leu Gln Leu Gly Tyr Lys 
            260                 265                 270         


Ala Ser Thr Asn Leu Gln Asp Gln Leu Glu Lys Thr Gly Glu Asn Lys 
        275                 280                 285             


Gly Trp Ser Gly Pro Lys Pro Gly Phe Pro Glu Pro Thr Asn Asn Thr 
    290                 295                 300                 


Pro Lys Gly Ile Leu His Leu Ser Pro Asp Val Tyr Gln Glu Met Glu 
305                 310                 315                 320 


Ala Ser Arg His Lys Val Ile Ser Gly Thr Thr Leu Gly Tyr Leu Ser 
                325                 330                 335     


Pro Lys Asp Met Asn Gln Pro Ser Ser Ser Phe Phe Ser Ile Ser Pro 
            340                 345                 350         


Thr Ser Asn Ser Ser Ala Thr Ile Ala Arg Glu Leu Leu Met Asn Gly 
        355                 360                 365             


Thr Ser Ser Thr Ala Glu Ala Ile Gly Leu Lys Gly Ser Ser Pro Thr 
    370                 375                 380                 


Pro Pro Cys Ser Pro Val Gln Pro Ser Lys Gln Leu Glu Tyr Leu Ala 
385                 390                 395                 400 


Arg Ile Gln Gly Phe Gln Val His Tyr Cys Asp Arg Gln Ser Gly Lys 
                405                 410                 415     


Glu Cys Val Thr Cys Leu Thr Leu Ala Pro Val Gln Met Thr Phe His 
            420                 425                 430         


Ala Ile Gly Ser Ser Ile Glu Ala Ser His Asp Gln Ala Ala Leu Ser 
        435                 440                 445             


Ala Leu Lys Gln Phe Ser Glu Gln Gly Leu Asp Pro Ile Asp Gly Ala 
    450                 455                 460                 


Met Asn Ile Glu Lys Gly Ser Leu Glu Lys Gln Ala Lys His Leu Arg 
465                 470                 475                 480 


Glu Lys Ala Asp Asn Asn Gln Ala Pro Pro Gly Ser Ile Ala Gln Asp 
                485                 490                 495     


Cys Lys Lys Ser Asn Ser Ala Val 
            500                 


<210>  4072
<211>  778
<212>  PRT
<213>  homo sapiens

<400>  4072

Met Asp Ser Lys Glu Ser Leu Thr Pro Gly Arg Glu Glu Asn Pro Ser 
1               5                   10                  15      


Ser Val Leu Ala Gln Glu Arg Gly Asp Val Met Asp Phe Tyr Lys Thr 
            20                  25                  30          


Leu Arg Gly Gly Ala Thr Val Lys Val Ser Ala Ser Ser Pro Ser Leu 
        35                  40                  45              


Ala Val Ala Ser Gln Ser Asp Ser Lys Gln Arg Arg Leu Leu Val Asp 
    50                  55                  60                  


Phe Pro Lys Gly Ser Val Ser Asn Ala Gln Gln Pro Asp Leu Ser Lys 
65                  70                  75                  80  


Ala Val Ser Leu Ser Met Gly Leu Tyr Met Gly Glu Thr Glu Thr Lys 
                85                  90                  95      


Val Met Gly Asn Asp Leu Gly Phe Pro Gln Gln Gly Gln Ile Ser Leu 
            100                 105                 110         


Ser Ser Gly Glu Thr Asp Leu Lys Leu Leu Glu Glu Ser Ile Ala Asn 
        115                 120                 125             


Leu Asn Arg Ser Thr Ser Val Pro Glu Asn Pro Lys Ser Ser Ala Ser 
    130                 135                 140                 


Thr Ala Val Ser Ala Ala Pro Thr Glu Lys Glu Phe Pro Lys Thr His 
145                 150                 155                 160 


Ser Asp Val Ser Ser Glu Gln Gln His Leu Lys Gly Gln Thr Gly Thr 
                165                 170                 175     


Asn Gly Gly Asn Val Lys Leu Tyr Thr Thr Asp Gln Ser Thr Phe Asp 
            180                 185                 190         


Ile Leu Gln Asp Leu Glu Phe Ser Ser Gly Ser Pro Gly Lys Glu Thr 
        195                 200                 205             


Asn Glu Ser Pro Trp Arg Ser Asp Leu Leu Ile Asp Glu Asn Cys Leu 
    210                 215                 220                 


Leu Ser Pro Leu Ala Gly Glu Asp Asp Ser Phe Leu Leu Glu Gly Asn 
225                 230                 235                 240 


Ser Asn Glu Asp Cys Lys Pro Leu Ile Leu Pro Asp Thr Lys Pro Lys 
                245                 250                 255     


Ile Lys Asp Asn Gly Asp Leu Val Leu Ser Ser Pro Ser Asn Val Thr 
            260                 265                 270         


Leu Pro Gln Val Lys Thr Glu Lys Glu Asp Phe Ile Glu Leu Cys Thr 
        275                 280                 285             


Pro Gly Val Ile Lys Gln Glu Lys Leu Gly Thr Val Tyr Cys Gln Ala 
    290                 295                 300                 


Ser Phe Pro Gly Ala Asn Ile Ile Gly Asn Lys Met Ser Ala Ile Ser 
305                 310                 315                 320 


Val His Gly Val Ser Thr Ser Gly Gly Gln Met Tyr His Tyr Asp Met 
                325                 330                 335     


Asn Thr Ala Ser Leu Ser Gln Gln Gln Asp Gln Lys Pro Ile Phe Asn 
            340                 345                 350         


Val Ile Pro Pro Ile Pro Val Gly Ser Glu Asn Trp Asn Arg Cys Gln 
        355                 360                 365             


Gly Ser Gly Asp Asp Asn Leu Thr Ser Leu Gly Thr Leu Asn Phe Pro 
    370                 375                 380                 


Gly Arg Thr Val Phe Ser Asn Gly Tyr Ser Ser Pro Ser Met Arg Pro 
385                 390                 395                 400 


Asp Val Ser Ser Pro Pro Ser Ser Ser Ser Thr Ala Thr Thr Gly Pro 
                405                 410                 415     


Pro Pro Lys Leu Cys Leu Val Cys Ser Asp Glu Ala Ser Gly Cys His 
            420                 425                 430         


Tyr Gly Val Leu Thr Cys Gly Ser Cys Lys Val Phe Phe Lys Arg Ala 
        435                 440                 445             


Val Glu Gly Arg Gln His Asn Tyr Leu Cys Ala Gly Arg Asn Asp Cys 
    450                 455                 460                 


Ile Ile Asp Lys Ile Arg Arg Lys Asn Cys Pro Ala Cys Arg Tyr Arg 
465                 470                 475                 480 


Lys Cys Leu Gln Ala Gly Met Asn Leu Glu Ala Arg Lys Thr Lys Lys 
                485                 490                 495     


Lys Ile Lys Gly Ile Gln Gln Ala Thr Thr Gly Val Ser Gln Glu Thr 
            500                 505                 510         


Ser Glu Asn Pro Gly Asn Lys Thr Ile Val Pro Ala Thr Leu Pro Gln 
        515                 520                 525             


Leu Thr Pro Thr Leu Val Ser Leu Leu Glu Val Ile Glu Pro Glu Val 
    530                 535                 540                 


Leu Tyr Ala Gly Tyr Asp Ser Ser Val Pro Asp Ser Thr Trp Arg Ile 
545                 550                 555                 560 


Met Thr Thr Leu Asn Met Leu Gly Gly Arg Gln Val Ile Ala Ala Val 
                565                 570                 575     


Lys Trp Ala Lys Ala Ile Pro Gly Phe Arg Asn Leu His Leu Asp Asp 
            580                 585                 590         


Gln Met Thr Leu Leu Gln Tyr Ser Trp Met Phe Leu Met Ala Phe Ala 
        595                 600                 605             


Leu Gly Trp Arg Ser Tyr Arg Gln Ser Ser Ala Asn Leu Leu Cys Phe 
    610                 615                 620                 


Ala Pro Asp Leu Ile Ile Asn Glu Gln Arg Met Thr Leu Pro Cys Met 
625                 630                 635                 640 


Tyr Asp Gln Cys Lys His Met Leu Tyr Val Ser Ser Glu Leu His Arg 
                645                 650                 655     


Leu Gln Val Ser Tyr Glu Glu Tyr Leu Cys Met Lys Thr Leu Leu Leu 
            660                 665                 670         


Leu Ser Ser Val Pro Lys Asp Gly Leu Lys Ser Gln Glu Leu Phe Asp 
        675                 680                 685             


Glu Ile Arg Met Thr Tyr Ile Lys Glu Leu Gly Lys Ala Ile Val Lys 
    690                 695                 700                 


Arg Glu Gly Asn Ser Ser Gln Asn Trp Gln Arg Phe Tyr Gln Leu Thr 
705                 710                 715                 720 


Lys Leu Leu Asp Ser Met His Glu Val Val Glu Asn Leu Leu Asn Tyr 
                725                 730                 735     


Cys Phe Gln Thr Phe Leu Asp Lys Thr Met Ser Ile Glu Phe Pro Glu 
            740                 745                 750         


Met Leu Ala Glu Ile Ile Thr Asn Gln Ile Pro Lys Tyr Ser Asn Gly 
        755                 760                 765             


Asn Ile Lys Lys Leu Leu Phe His Gln Lys 
    770                 775             


<210>  4073
<211>  381
<212>  PRT
<213>  homo sapiens

<400>  4073

Met Ser Cys Leu His Pro Arg Gln Thr Trp Lys Gly Ala Ala Leu Val 
1               5                   10                  15      


His Arg Lys Ala Trp Trp Met Gly Arg Ser Leu Asp Gly Arg Leu Gln 
            20                  25                  30          


Val Ser His Arg Lys Gly Leu Pro His Val Ile Tyr Cys Arg Leu Trp 
        35                  40                  45              


Arg Trp Pro Asp Leu His Ser His His Glu Leu Arg Ala Met Glu Leu 
    50                  55                  60                  


Cys Glu Phe Ala Phe Asn Met Lys Lys Asp Glu Val Cys Val Asn Pro 
65                  70                  75                  80  


Tyr His Tyr Gln Arg Val Glu Thr Pro Val Leu Pro Pro Val Leu Val 
                85                  90                  95      


Pro Arg His Thr Glu Ile Pro Ala Glu Phe Pro Pro Leu Asp Asp Tyr 
            100                 105                 110         


Ser His Ser Ile Pro Glu Asn Thr Asn Phe Pro Ala Gly Ile Glu Pro 
        115                 120                 125             


Gln Ser Asn Ile Pro Glu Thr Pro Pro Pro Gly Tyr Leu Ser Glu Asp 
    130                 135                 140                 


Gly Glu Thr Ser Asp His Gln Met Asn His Ser Met Asp Ala Gly Ser 
145                 150                 155                 160 


Pro Asn Leu Ser Pro Asn Pro Met Ser Pro Ala His Asn Asn Leu Asp 
                165                 170                 175     


Leu Gln Pro Val Thr Tyr Cys Glu Pro Ala Phe Trp Cys Ser Ile Ser 
            180                 185                 190         


Tyr Tyr Glu Leu Asn Gln Arg Val Gly Glu Thr Phe His Ala Ser Gln 
        195                 200                 205             


Pro Ser Met Thr Val Asp Gly Phe Thr Asp Pro Ser Asn Ser Glu Arg 
    210                 215                 220                 


Phe Cys Leu Gly Leu Leu Ser Asn Val Asn Arg Asn Ala Ala Val Glu 
225                 230                 235                 240 


Leu Thr Arg Arg His Ile Gly Arg Gly Val Arg Leu Tyr Tyr Ile Gly 
                245                 250                 255     


Gly Glu Val Phe Ala Glu Cys Leu Ser Asp Ser Ala Ile Phe Val Gln 
            260                 265                 270         


Ser Pro Asn Cys Asn Gln Arg Tyr Gly Trp His Pro Ala Thr Val Cys 
        275                 280                 285             


Lys Ile Pro Pro Gly Cys Asn Leu Lys Ile Phe Asn Asn Gln Glu Phe 
    290                 295                 300                 


Ala Ala Leu Leu Ala Gln Ser Val Asn Gln Gly Phe Glu Ala Val Tyr 
305                 310                 315                 320 


Gln Leu Thr Arg Met Cys Thr Ile Arg Met Ser Phe Val Lys Gly Trp 
                325                 330                 335     


Gly Ala Glu Tyr Arg Arg Gln Thr Val Thr Ser Thr Pro Cys Trp Ile 
            340                 345                 350         


Glu Leu His Leu Asn Gly Pro Leu Gln Trp Leu Asp Lys Val Leu Thr 
        355                 360                 365             


Gln Met Gly Ser Pro Ser Ile Arg Cys Ser Ser Val Ser 
    370                 375                 380     


<210>  4074
<211>  230
<212>  PRT
<213>  homo sapiens

<400>  4074

Met Asn His Ser Met Asp Ala Gly Ser Pro Asn Leu Ser Pro Asn Pro 
1               5                   10                  15      


Met Ser Pro Ala His Asn Asn Leu Asp Leu Gln Pro Val Thr Tyr Cys 
            20                  25                  30          


Glu Pro Ala Phe Trp Cys Ser Ile Ser Tyr Tyr Glu Leu Asn Gln Arg 
        35                  40                  45              


Val Gly Glu Thr Phe His Ala Ser Gln Pro Ser Met Thr Val Asp Gly 
    50                  55                  60                  


Phe Thr Asp Pro Ser Asn Ser Glu Arg Phe Cys Leu Gly Leu Leu Ser 
65                  70                  75                  80  


Asn Val Asn Arg Asn Ala Ala Val Glu Leu Thr Arg Arg His Ile Gly 
                85                  90                  95      


Arg Gly Val Arg Leu Tyr Tyr Ile Gly Gly Glu Val Phe Ala Glu Cys 
            100                 105                 110         


Leu Ser Asp Ser Ala Ile Phe Val Gln Ser Pro Asn Cys Asn Gln Arg 
        115                 120                 125             


Tyr Gly Trp His Pro Ala Thr Val Cys Lys Ile Pro Pro Gly Cys Asn 
    130                 135                 140                 


Leu Lys Ile Phe Asn Asn Gln Glu Phe Ala Ala Leu Leu Ala Gln Ser 
145                 150                 155                 160 


Val Asn Gln Gly Phe Glu Ala Val Tyr Gln Leu Thr Arg Met Cys Thr 
                165                 170                 175     


Ile Arg Met Ser Phe Val Lys Gly Trp Gly Ala Glu Tyr Arg Arg Gln 
            180                 185                 190         


Thr Val Thr Ser Thr Pro Cys Trp Ile Glu Leu His Leu Asn Gly Pro 
        195                 200                 205             


Leu Gln Trp Leu Asp Lys Val Leu Thr Gln Met Gly Ser Pro Ser Ile 
    210                 215                 220                 


Arg Cys Ser Ser Val Ser 
225                 230 


<210>  4075
<211>  1223
<212>  PRT
<213>  homo sapiens

<400>  4075

Met Arg Arg Leu Ala Ala Glu Glu Leu Gly Val Val Thr Met Gln Arg 
1               5                   10                  15      


Ile Phe Asn Ser Phe Val Tyr Thr Glu Lys Ile Ser Asn Gly Glu Ser 
            20                  25                  30          


Glu Val Gln Gln Leu Ala Lys Lys Ile Arg Glu Lys Phe Asn Arg Tyr 
        35                  40                  45              


Leu Asp Val Val Asn Arg Asn Lys Gln Val Val Glu Ala Ser Tyr Thr 
    50                  55                  60                  


Ala His Leu Thr Ser Pro Leu Thr Ala Ile Gln Asp Cys Cys Thr Ile 
65                  70                  75                  80  


Pro Pro Ser Met Met Glu Phe Asp Gly Asn Phe Asn Thr Asn Val Ser 
                85                  90                  95      


Arg Thr Ile Ser Cys Asp Arg Leu Ser Thr Thr Val Asn Ser Arg Ala 
            100                 105                 110         


Phe Asn Pro Gly Arg Asp Leu Asn Ser Val Leu Ala Asp Asn Leu Lys 
        115                 120                 125             


Ser Asn Pro Gly Ile Lys Trp Gln Tyr Phe Ser Ser Glu Glu Gly Ile 
    130                 135                 140                 


Phe Thr Val Phe Pro Ala His Lys Phe Arg Cys Lys Gly Ser Tyr Glu 
145                 150                 155                 160 


His Arg Ser Arg Pro Ile Tyr Val Ser Thr Val Arg Pro Gln Ser Lys 
                165                 170                 175     


His Ile Val Val Ile Leu Asp His Gly Ala Ser Val Thr Asp Thr Gln 
            180                 185                 190         


Leu Gln Ile Ala Lys Asp Ala Ala Gln Val Ile Leu Ser Ala Ile Asp 
        195                 200                 205             


Glu His Asp Lys Ile Ser Val Leu Thr Val Ala Asp Thr Val Arg Thr 
    210                 215                 220                 


Cys Ser Leu Asp Gln Cys Tyr Lys Thr Phe Leu Ser Pro Ala Thr Ser 
225                 230                 235                 240 


Glu Thr Lys Arg Lys Met Ser Thr Phe Val Ser Ser Val Lys Ser Ser 
                245                 250                 255     


Asp Ser Pro Thr Gln His Ala Val Gly Phe Gln Lys Ala Phe Gln Leu 
            260                 265                 270         


Ile Arg Ser Thr Asn Asn Asn Thr Lys Phe Gln Ala Asn Thr Asp Met 
        275                 280                 285             


Val Ile Ile Tyr Leu Ser Ala Gly Ile Thr Ser Lys Asp Ser Ser Glu 
    290                 295                 300                 


Glu Asp Lys Lys Ala Thr Leu Gln Val Ile Asn Glu Glu Asn Ser Phe 
305                 310                 315                 320 


Leu Asn Asn Ser Val Met Ile Leu Thr Tyr Ala Leu Met Asn Asp Gly 
                325                 330                 335     


Val Thr Gly Leu Lys Glu Leu Ala Phe Leu Arg Asp Leu Ala Glu Gln 
            340                 345                 350         


Asn Ser Gly Lys Tyr Gly Val Pro Asp Arg Met Ala Leu Pro Val Ile 
        355                 360                 365             


Lys Gly Ser Met Met Val Leu Asn Gln Leu Ser Asn Leu Glu Thr Thr 
    370                 375                 380                 


Val Gly Arg Phe Tyr Thr Asn Leu Pro Asn Arg Met Ile Asp Glu Ala 
385                 390                 395                 400 


Val Phe Ser Leu Pro Phe Ser Asp Glu Met Gly Asp Gly Leu Ile Met 
                405                 410                 415     


Thr Val Ser Lys Pro Cys Tyr Phe Gly Asn Leu Leu Leu Gly Ile Val 
            420                 425                 430         


Gly Val Asp Val Asn Leu Ala Tyr Ile Leu Glu Asp Val Thr Tyr Tyr 
        435                 440                 445             


Gln Asp Ser Leu Ala Ser Tyr Thr Phe Leu Ile Asp Asp Lys Gly Tyr 
    450                 455                 460                 


Thr Leu Met His Pro Ser Leu Thr Arg Pro Tyr Leu Leu Ser Glu Pro 
465                 470                 475                 480 


Pro Leu His Thr Asp Ile Ile His Tyr Glu Asn Ile Pro Lys Phe Glu 
                485                 490                 495     


Leu Val Arg Gln Asn Ile Leu Ser Leu Pro Leu Gly Ser Gln Ile Ile 
            500                 505                 510         


Ala Val Pro Val Asn Ser Ser Leu Ser Trp His Ile Asn Lys Leu Arg 
        515                 520                 525             


Glu Thr Gly Lys Glu Ala Tyr Asn Val Ser Tyr Ala Trp Lys Met Val 
    530                 535                 540                 


Gln Asp Thr Ser Phe Ile Leu Cys Ile Val Val Ile Gln Pro Glu Ile 
545                 550                 555                 560 


Pro Val Lys Gln Leu Lys Asn Leu Asn Thr Val Pro Ser Ser Lys Leu 
                565                 570                 575     


Leu Tyr His Arg Leu Asp Leu Leu Gly Gln Pro Ser Ala Cys Leu His 
            580                 585                 590         


Phe Lys Gln Leu Ala Thr Leu Glu Ser Pro Thr Ile Met Leu Ser Ala 
        595                 600                 605             


Gly Ser Phe Ser Ser Pro Tyr Glu His Leu Ser Gln Pro Glu Thr Lys 
    610                 615                 620                 


Arg Met Val Glu His Tyr Thr Ala Tyr Leu Ser Asp Asn Thr Arg Leu 
625                 630                 635                 640 


Ile Ala Asn Pro Gly Leu Lys Phe Ser Val Arg Asn Glu Val Met Ala 
                645                 650                 655     


Thr Ser His Val Thr Asp Glu Trp Met Thr Gln Met Glu Met Ser Ser 
            660                 665                 670         


Leu Asn Thr Tyr Ile Val Arg Arg Tyr Ile Ala Thr Pro Asn Gly Val 
        675                 680                 685             


Leu Arg Ile Tyr Pro Gly Ser Leu Met Asp Lys Ala Phe Asp Pro Thr 
    690                 695                 700                 


Arg Arg Gln Trp Tyr Leu His Ala Val Ala Asn Pro Gly Leu Ile Ser 
705                 710                 715                 720 


Leu Thr Gly Pro Tyr Leu Asp Val Gly Gly Ala Gly Tyr Val Val Thr 
                725                 730                 735     


Ile Ser His Thr Ile His Ser Ser Ser Thr Gln Leu Ser Ser Gly His 
            740                 745                 750         


Thr Val Ala Val Met Gly Ile Asp Phe Thr Leu Arg Tyr Phe Tyr Lys 
        755                 760                 765             


Val Leu Met Asp Leu Leu Pro Val Cys Asn Gln Asp Gly Gly Asn Lys 
    770                 775                 780                 


Ile Arg Cys Phe Ile Met Glu Asp Arg Gly Tyr Leu Val Ala His Pro 
785                 790                 795                 800 


Thr Leu Ile Asp Pro Lys Gly His Ala Pro Val Glu Gln Gln His Ile 
                805                 810                 815     


Thr His Lys Glu Pro Leu Val Ala Asn Asp Ile Leu Asn His Pro Asn 
            820                 825                 830         


Phe Val Lys Lys Asn Leu Cys Asn Ser Phe Ser Asp Arg Thr Val Gln 
        835                 840                 845             


Arg Phe Tyr Lys Phe Asn Thr Ser Leu Ala Gly Asp Leu Thr Asn Leu 
    850                 855                 860                 


Val His Gly Ser His Cys Ser Lys Tyr Arg Leu Ala Arg Ile Pro Gly 
865                 870                 875                 880 


Thr Asn Ala Phe Val Gly Ile Val Asn Glu Thr Cys Asp Ser Leu Ala 
                885                 890                 895     


Phe Cys Ala Cys Ser Met Val Asp Arg Leu Cys Leu Asn Cys His Arg 
            900                 905                 910         


Met Glu Gln Asn Glu Cys Glu Cys Pro Cys Glu Cys Pro Leu Glu Val 
        915                 920                 925             


Asn Glu Cys Thr Gly Asn Leu Thr Asn Ala Glu Asn Arg Asn Pro Ser 
    930                 935                 940                 


Cys Glu Val His Gln Glu Pro Val Thr Tyr Thr Ala Ile Asp Pro Gly 
945                 950                 955                 960 


Leu Gln Asp Ala Leu His Gln Cys Val Asn Ser Arg Cys Ser Gln Arg 
                965                 970                 975     


Leu Glu Ser Gly Asp Cys Phe Gly Val Leu Asp Cys Glu Trp Cys Met 
            980                 985                 990         


Val Asp Ser Asp Gly Lys Thr His  Leu Asp Lys Pro Tyr  Cys Ala Pro 
        995                 1000                 1005             


Gln Lys  Glu Cys Phe Gly Gly  Ile Val Gly Ala Lys  Ser Pro Tyr 
    1010                 1015                 1020             


Val Asp  Asp Met Gly Ala Ile  Gly Asp Glu Val Ile  Thr Leu Asn 
    1025                 1030                 1035             


Met Ile  Lys Ser Ala Pro Val  Gly Pro Val Ala Gly  Gly Ile Met 
    1040                 1045                 1050             


Gly Cys  Ile Met Val Leu Val  Leu Ala Val Tyr Ala  Tyr Arg His 
    1055                 1060                 1065             


Gln Ile  His Arg Arg Ser His  Gln His Met Ser Pro  Leu Ala Ala 
    1070                 1075                 1080             


Gln Glu  Met Ser Val Arg Met  Ser Asn Leu Glu Asn  Asp Arg Asp 
    1085                 1090                 1095             


Glu Arg  Asp Asp Asp Ser His  Glu Asp Arg Gly Ile  Ile Ser Asn 
    1100                 1105                 1110             


Thr Arg  Phe Ile Ala Ala Val  Ile Glu Arg His Ala  His Ser Pro 
    1115                 1120                 1125             


Glu Arg  Arg Arg Arg Tyr Trp  Gly Arg Ser Gly Thr  Glu Ser Asp 
    1130                 1135                 1140             


His Gly  Tyr Ser Thr Met Ser  Pro Gln Glu Asp Ser  Glu Asn Pro 
    1145                 1150                 1155             


Pro Cys  Asn Asn Asp Pro Leu  Ser Ala Gly Val Asp  Val Gly Asn 
    1160                 1165                 1170             


His Asp  Glu Asp Leu Asp Leu  Asp Thr Pro Pro Gln  Thr Ala Ala 
    1175                 1180                 1185             


Leu Leu  Ser His Lys Phe His  His Tyr Arg Ser His  His Pro Thr 
    1190                 1195                 1200             


Leu His  His Ser His His Leu  Gln Ala Ala Val Thr  Val His Thr 
    1205                 1210                 1215             


Val Asp  Ala Glu Cys 
    1220             


<210>  4076
<211>  401
<212>  PRT
<213>  homo sapiens

<400>  4076

Met Arg Arg Ala Pro Ala Ala Glu Arg Leu Leu Glu Leu Gly Phe Pro 
1               5                   10                  15      


Pro Arg Cys Gly Arg Gln Glu Pro Pro Phe Pro Leu Gly Val Thr Arg 
            20                  25                  30          


Gly Trp Gly Arg Trp Pro Ile Gln Lys Arg Arg Glu Gly Ala Arg Pro 
        35                  40                  45              


Val Pro Phe Ser Glu Arg Ser Gln Glu Asp Gly Arg Gly Pro Ala Ala 
    50                  55                  60                  


Arg Ser Ser Gly Thr Leu Trp Arg Ile Arg Thr Arg Leu Ser Leu Cys 
65                  70                  75                  80  


Arg Asp Pro Glu Pro Pro Pro Pro Leu Cys Leu Leu Arg Val Ser Leu 
                85                  90                  95      


Leu Cys Ala Leu Arg Ala Gly Gly Arg Gly Ser Arg Trp Gly Glu Asp 
            100                 105                 110         


Gly Ala Arg Leu Leu Leu Leu Pro Pro Ala Arg Ala Ala Gly Asn Gly 
        115                 120                 125             


Glu Ala Glu Pro Ser Gly Gly Pro Ser Tyr Ala Gly Arg Met Leu Glu 
    130                 135                 140                 


Ser Ser Gly Cys Lys Ala Leu Lys Glu Gly Val Leu Glu Lys Arg Ser 
145                 150                 155                 160 


Asp Gly Leu Leu Gln Leu Trp Lys Lys Lys Cys Cys Ile Leu Thr Glu 
                165                 170                 175     


Glu Gly Leu Leu Leu Ile Pro Pro Lys Gln Leu Gln His Gln Gln Gln 
            180                 185                 190         


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Pro Gly Gln Gly 
        195                 200                 205             


Pro Ala Glu Pro Ser Gln Pro Ser Gly Pro Ala Val Ala Ser Leu Glu 
    210                 215                 220                 


Pro Pro Val Lys Leu Lys Glu Leu His Phe Ser Asn Met Lys Thr Val 
225                 230                 235                 240 


Asp Cys Val Glu Arg Lys Gly Lys Tyr Met Tyr Phe Thr Val Val Met 
                245                 250                 255     


Ala Glu Gly Lys Glu Ile Asp Phe Arg Cys Pro Gln Asp Gln Gly Trp 
            260                 265                 270         


Asn Ala Glu Ile Thr Leu Gln Met Val Gln Tyr Lys Asn Arg Gln Ala 
        275                 280                 285             


Ile Leu Ala Val Lys Ser Thr Arg Gln Lys Gln Gln His Leu Val Gln 
    290                 295                 300                 


Gln Gln Pro Pro Ser Gln Pro Gln Pro Gln Pro Gln Leu Gln Pro Gln 
305                 310                 315                 320 


Pro Gln Pro Gln Pro Gln Pro Gln Pro Gln Pro Gln Ser Gln Pro Gln 
                325                 330                 335     


Pro Gln Pro Gln Pro Lys Pro Gln Pro Gln Gln Leu His Pro Tyr Pro 
            340                 345                 350         


His Pro His Pro His Pro His Ser His Pro His Ser His Pro His Pro 
        355                 360                 365             


His Pro His Pro His Pro His Gln Ile Pro His Pro His Pro Gln Pro 
    370                 375                 380                 


His Ser Gln Pro His Gly His Arg Leu Leu Arg Ser Thr Ser Asn Ser 
385                 390                 395                 400 


Ala 
    


<210>  4077
<211>  348
<212>  PRT
<213>  homo sapiens

<400>  4077

Met Ser Leu Val Asp Leu Gly Lys Lys Leu Leu Glu Ala Ala Arg Ala 
1               5                   10                  15      


Gly Gln Asp Asp Glu Val Arg Ile Leu Met Ala Asn Gly Ala Pro Phe 
            20                  25                  30          


Thr Thr Asp Trp Leu Gly Thr Ser Pro Leu His Leu Ala Ala Gln Tyr 
        35                  40                  45              


Gly His Tyr Ser Thr Thr Glu Val Leu Leu Arg Ala Gly Val Ser Arg 
    50                  55                  60                  


Asp Ala Arg Thr Lys Val Asp Arg Thr Pro Leu His Met Ala Ala Ser 
65                  70                  75                  80  


Glu Gly His Ala Ser Ile Val Glu Val Leu Leu Lys His Gly Ala Asp 
                85                  90                  95      


Val Asn Ala Lys Asp Met Leu Lys Met Thr Ala Leu His Trp Ala Thr 
            100                 105                 110         


Glu His Asn His Gln Glu Val Val Glu Leu Leu Ile Lys Tyr Gly Ala 
        115                 120                 125             


Asp Val His Thr Gln Ser Lys Phe Cys Lys Thr Ala Phe Asp Ile Ser 
    130                 135                 140                 


Ile Asp Asn Gly Asn Glu Asp Leu Ala Glu Ile Leu Gln Ile Ala Met 
145                 150                 155                 160 


Gln Asn Gln Ile Asn Thr Asn Pro Glu Ser Pro Asp Thr Val Thr Ile 
                165                 170                 175     


His Ala Ala Thr Pro Gln Phe Ile Ile Gly Pro Gly Gly Val Val Asn 
            180                 185                 190         


Leu Thr Asp Glu Thr Gly Val Ser Ala Val Gln Phe Gly Asn Ser Ser 
        195                 200                 205             


Thr Ser Val Leu Ala Thr Leu Ala Ala Leu Ala Glu Ala Ser Ala Pro 
    210                 215                 220                 


Leu Ser Asn Ser Ser Glu Thr Pro Val Val Ala Thr Glu Glu Val Val 
225                 230                 235                 240 


Thr Ala Glu Ser Val Asp Gly Ala Ile Gln Gln Val Val Ser Ser Gly 
                245                 250                 255     


Gly Gln Gln Val Ile Thr Ile Val Thr Asp Gly Ile Gln Leu Gly Asn 
            260                 265                 270         


Leu His Ser Ile Pro Thr Ser Gly Ile Gly Gln Pro Ile Ile Val Thr 
        275                 280                 285             


Met Pro Asp Gly Gln Gln Val Leu Thr Val Pro Ala Thr Asp Ile Ala 
    290                 295                 300                 


Glu Glu Thr Val Ile Ser Glu Glu Pro Pro Ala Lys Arg Gln Cys Ile 
305                 310                 315                 320 


Glu Ile Ile Glu Asn Arg Val Glu Ser Ala Glu Ile Glu Val Arg Ser 
                325                 330                 335     


Leu Leu Pro Gly Val Leu Cys Arg Ser His Pro Lys 
            340                 345             


<210>  4078
<211>  322
<212>  PRT
<213>  homo sapiens

<400>  4078

Met Pro Val Thr Val Thr Arg Thr Thr Ile Thr Thr Thr Thr Thr Ser 
1               5                   10                  15      


Ser Ser Gly Leu Gly Ser Pro Met Ile Val Gly Ser Pro Arg Ala Leu 
            20                  25                  30          


Thr Gln Pro Leu Gly Leu Leu Arg Leu Leu Gln Leu Val Ser Thr Cys 
        35                  40                  45              


Val Ala Phe Ser Leu Val Ala Ser Val Gly Ala Trp Thr Gly Ser Met 
    50                  55                  60                  


Gly Asn Trp Ser Met Phe Thr Trp Cys Phe Cys Phe Ser Val Thr Leu 
65                  70                  75                  80  


Ile Ile Leu Ile Val Glu Leu Cys Gly Leu Gln Ala Arg Phe Pro Leu 
                85                  90                  95      


Ser Trp Arg Asn Phe Pro Ile Thr Phe Ala Cys Tyr Ala Ala Leu Phe 
            100                 105                 110         


Cys Leu Ser Ala Ser Ile Ile Tyr Pro Thr Thr Tyr Val Gln Phe Leu 
        115                 120                 125             


Ser His Gly Arg Ser Arg Asp His Ala Ile Ala Ala Thr Phe Phe Ser 
    130                 135                 140                 


Cys Ile Ala Cys Val Ala Tyr Ala Thr Glu Val Ala Trp Thr Arg Ala 
145                 150                 155                 160 


Arg Pro Gly Glu Ile Thr Gly Tyr Met Ala Thr Val Pro Gly Leu Leu 
                165                 170                 175     


Lys Val Leu Glu Thr Phe Val Ala Cys Ile Ile Phe Ala Phe Ile Ser 
            180                 185                 190         


Asp Pro Asn Leu Tyr Gln His Gln Pro Ala Leu Glu Trp Cys Val Ala 
        195                 200                 205             


Val Tyr Ala Ile Cys Phe Ile Leu Ala Ala Ile Ala Ile Leu Leu Asn 
    210                 215                 220                 


Leu Gly Glu Cys Thr Asn Val Leu Pro Ile Pro Phe Pro Ser Phe Leu 
225                 230                 235                 240 


Ser Gly Leu Ala Leu Leu Ser Val Leu Leu Tyr Ala Thr Ala Leu Val 
                245                 250                 255     


Leu Trp Pro Leu Tyr Gln Phe Asp Glu Lys Tyr Gly Gly Gln Pro Arg 
            260                 265                 270         


Arg Ser Arg Asp Val Ser Cys Ser Arg Ser His Ala Tyr Tyr Val Cys 
        275                 280                 285             


Ala Trp Asp Arg Arg Leu Ala Val Ala Ile Leu Thr Ala Ile Asn Leu 
    290                 295                 300                 


Leu Ala Tyr Val Ala Asp Leu Val His Ser Ala His Leu Val Phe Val 
305                 310                 315                 320 


Lys Val 
        


<210>  4079
<211>  731
<212>  PRT
<213>  homo sapiens

<400>  4079

Met Val Val Glu His Pro Glu Phe Leu Lys Ala Gly Lys Glu Pro Gly 
1               5                   10                  15      


Leu Gln Ile Trp Arg Val Glu Lys Phe Asp Leu Val Pro Val Pro Thr 
            20                  25                  30          


Asn Leu Tyr Gly Asp Phe Phe Thr Gly Asp Ala Tyr Val Ile Leu Lys 
        35                  40                  45              


Thr Val Gln Leu Arg Asn Gly Asn Leu Gln Tyr Asp Leu His Tyr Trp 
    50                  55                  60                  


Leu Gly Asn Glu Cys Ser Gln Asp Glu Ser Gly Ala Ala Ala Ile Phe 
65                  70                  75                  80  


Thr Val Gln Leu Asp Asp Tyr Leu Asn Gly Arg Ala Val Gln His Arg 
                85                  90                  95      


Glu Val Gln Gly Phe Glu Ser Ala Thr Phe Leu Gly Tyr Phe Lys Ser 
            100                 105                 110         


Gly Leu Lys Tyr Lys Lys Gly Gly Val Ala Ser Gly Phe Lys His Val 
        115                 120                 125             


Val Pro Asn Glu Val Val Val Gln Arg Leu Phe Gln Val Lys Gly Arg 
    130                 135                 140                 


Arg Val Val Arg Ala Thr Glu Val Pro Val Ser Trp Glu Ser Phe Asn 
145                 150                 155                 160 


Asn Gly Asp Cys Phe Ile Leu Asp Leu Gly Asn Asn Ile His Gln Trp 
                165                 170                 175     


Cys Gly Ser Asn Ser Asn Arg Tyr Glu Arg Leu Lys Ala Thr Gln Val 
            180                 185                 190         


Ser Lys Gly Ile Arg Asp Asn Glu Arg Ser Gly Arg Ala Arg Val His 
        195                 200                 205             


Val Ser Glu Glu Gly Thr Glu Pro Glu Ala Met Leu Gln Val Leu Gly 
    210                 215                 220                 


Pro Lys Pro Ala Leu Pro Ala Gly Thr Glu Asp Thr Ala Lys Glu Asp 
225                 230                 235                 240 


Ala Ala Asn Arg Lys Leu Ala Lys Leu Tyr Lys Val Ser Asn Gly Ala 
                245                 250                 255     


Gly Thr Met Ser Val Ser Leu Val Ala Asp Glu Asn Pro Phe Ala Gln 
            260                 265                 270         


Gly Ala Leu Lys Ser Glu Asp Cys Phe Ile Leu Asp His Gly Lys Asp 
        275                 280                 285             


Gly Lys Ile Phe Val Trp Lys Gly Lys Gln Ala Asn Thr Glu Glu Arg 
    290                 295                 300                 


Lys Ala Ala Leu Lys Thr Ala Ser Asp Phe Ile Thr Lys Met Asp Tyr 
305                 310                 315                 320 


Pro Lys Gln Thr Gln Val Ser Val Leu Pro Glu Gly Gly Glu Thr Pro 
                325                 330                 335     


Leu Phe Lys Gln Phe Phe Lys Asn Trp Arg Asp Pro Asp Gln Thr Asp 
            340                 345                 350         


Gly Leu Gly Leu Ser Tyr Leu Ser Ser His Ile Ala Asn Val Glu Arg 
        355                 360                 365             


Val Pro Phe Asp Ala Ala Thr Leu His Thr Ser Thr Ala Met Ala Ala 
    370                 375                 380                 


Gln His Gly Met Asp Asp Asp Gly Thr Gly Gln Lys Gln Ile Trp Arg 
385                 390                 395                 400 


Ile Glu Gly Ser Asn Lys Val Pro Val Asp Pro Ala Thr Tyr Gly Gln 
                405                 410                 415     


Phe Tyr Gly Gly Asp Ser Tyr Ile Ile Leu Tyr Asn Tyr Arg His Gly 
            420                 425                 430         


Gly Arg Gln Gly Gln Ile Ile Tyr Asn Trp Gln Gly Ala Gln Ser Thr 
        435                 440                 445             


Gln Asp Glu Val Ala Ala Ser Ala Ile Leu Thr Ala Gln Leu Asp Glu 
    450                 455                 460                 


Glu Leu Gly Gly Thr Pro Val Gln Ser Arg Val Val Gln Gly Lys Glu 
465                 470                 475                 480 


Pro Ala His Leu Met Ser Leu Phe Gly Gly Lys Pro Met Ile Ile Tyr 
                485                 490                 495     


Lys Gly Gly Thr Ser Arg Glu Gly Gly Gln Thr Ala Pro Ala Ser Thr 
            500                 505                 510         


Arg Leu Phe Gln Val Arg Ala Asn Ser Ala Gly Ala Thr Arg Ala Val 
        515                 520                 525             


Glu Val Leu Pro Lys Ala Gly Ala Leu Asn Ser Asn Asp Ala Phe Val 
    530                 535                 540                 


Leu Lys Thr Pro Ser Ala Ala Tyr Leu Trp Val Gly Thr Gly Ala Ser 
545                 550                 555                 560 


Glu Ala Glu Lys Thr Gly Ala Gln Glu Leu Leu Arg Val Leu Arg Ala 
                565                 570                 575     


Gln Pro Val Gln Val Ala Glu Gly Ser Glu Pro Asp Gly Phe Trp Glu 
            580                 585                 590         


Ala Leu Gly Gly Lys Ala Ala Tyr Arg Thr Ser Pro Arg Leu Lys Asp 
        595                 600                 605             


Lys Lys Met Asp Ala His Pro Pro Arg Leu Phe Ala Cys Ser Asn Lys 
    610                 615                 620                 


Ile Gly Arg Phe Val Ile Glu Glu Val Pro Gly Glu Leu Met Gln Glu 
625                 630                 635                 640 


Asp Leu Ala Thr Asp Asp Val Met Leu Leu Asp Thr Trp Asp Gln Val 
                645                 650                 655     


Phe Val Trp Val Gly Lys Asp Ser Gln Glu Glu Glu Lys Thr Glu Ala 
            660                 665                 670         


Leu Thr Ser Ala Lys Arg Tyr Ile Glu Thr Asp Pro Ala Asn Arg Asp 
        675                 680                 685             


Arg Arg Thr Pro Ile Thr Val Val Lys Gln Gly Phe Glu Pro Pro Ser 
    690                 695                 700                 


Phe Val Gly Trp Phe Leu Gly Trp Asp Asp Asp Tyr Trp Ser Val Asp 
705                 710                 715                 720 


Pro Leu Asp Arg Ala Met Ala Glu Leu Ala Ala 
                725                 730     


<210>  4080
<211>  344
<212>  PRT
<213>  homo sapiens

<400>  4080

Met Ala Gln Lys Glu Asn Ser Tyr Pro Trp Pro Tyr Gly Arg Gln Thr 
1               5                   10                  15      


Ala Pro Ser Gly Leu Ser Thr Leu Pro Gln Arg Val Leu Arg Lys Glu 
            20                  25                  30          


Pro Val Thr Pro Ser Ala Leu Val Leu Met Ser Arg Ser Asn Val Gln 
        35                  40                  45              


Pro Thr Ala Ala Pro Gly Gln Lys Val Met Glu Asn Ser Ser Gly Thr 
    50                  55                  60                  


Pro Asp Ile Leu Thr Arg His Phe Thr Ile Asp Asp Phe Glu Ile Gly 
65                  70                  75                  80  


Arg Pro Leu Gly Lys Gly Lys Phe Gly Asn Val Tyr Leu Ala Arg Glu 
                85                  90                  95      


Lys Lys Ser His Phe Ile Val Ala Leu Lys Val Leu Phe Lys Ser Gln 
            100                 105                 110         


Ile Glu Lys Glu Gly Val Glu His Gln Leu Arg Arg Glu Ile Glu Ile 
        115                 120                 125             


Gln Ala His Leu His His Pro Asn Ile Leu Arg Leu Tyr Asn Tyr Phe 
    130                 135                 140                 


Tyr Asp Arg Arg Arg Ile Tyr Leu Ile Leu Glu Tyr Ala Pro Arg Gly 
145                 150                 155                 160 


Glu Leu Tyr Lys Glu Leu Gln Lys Ser Cys Thr Phe Asp Glu Gln Arg 
                165                 170                 175     


Thr Ala Thr Ile Met Glu Glu Leu Ala Asp Ala Leu Met Tyr Cys His 
            180                 185                 190         


Gly Lys Lys Val Ile His Arg Asp Ile Lys Pro Glu Asn Leu Leu Leu 
        195                 200                 205             


Gly Leu Lys Gly Glu Leu Lys Ile Ala Asp Phe Gly Trp Ser Val His 
    210                 215                 220                 


Ala Pro Ser Leu Arg Arg Lys Thr Met Cys Gly Thr Leu Asp Tyr Leu 
225                 230                 235                 240 


Pro Pro Glu Met Ile Glu Gly Arg Met His Asn Glu Lys Val Asp Leu 
                245                 250                 255     


Trp Cys Ile Gly Val Leu Cys Tyr Glu Leu Leu Val Gly Asn Pro Pro 
            260                 265                 270         


Phe Glu Ser Ala Ser His Asn Glu Thr Tyr Arg Arg Ile Val Lys Val 
        275                 280                 285             


Asp Leu Lys Phe Pro Ala Ser Val Pro Met Gly Ala Gln Asp Leu Ile 
    290                 295                 300                 


Ser Lys Leu Leu Arg His Asn Pro Ser Glu Arg Leu Pro Leu Ala Gln 
305                 310                 315                 320 


Val Ser Ala His Pro Trp Val Arg Ala Asn Ser Arg Arg Val Leu Pro 
                325                 330                 335     


Pro Ser Ala Leu Gln Ser Val Ala 
            340                 


<210>  4081
<211>  268
<212>  PRT
<213>  homo sapiens

<400>  4081

Met Leu Leu Lys Glu Tyr Arg Ile Cys Met Pro Leu Thr Val Asp Glu 
1               5                   10                  15      


Tyr Lys Ile Gly Gln Leu Tyr Met Ile Ser Lys His Ser His Glu Gln 
            20                  25                  30          


Ser Asp Arg Gly Glu Gly Val Glu Val Val Gln Asn Glu Pro Phe Glu 
        35                  40                  45              


Asp Pro His His Gly Asn Gly Gln Phe Thr Glu Lys Arg Val Tyr Leu 
    50                  55                  60                  


Asn Ser Lys Leu Pro Ser Trp Ala Arg Ala Val Val Pro Lys Ile Phe 
65                  70                  75                  80  


Tyr Val Thr Glu Lys Ala Trp Asn Tyr Tyr Pro Tyr Thr Ile Thr Glu 
                85                  90                  95      


Tyr Thr Cys Ser Phe Leu Pro Lys Phe Ser Ile His Ile Glu Thr Lys 
            100                 105                 110         


Tyr Glu Asp Asn Lys Gly Ser Asn Asp Thr Ile Phe Asp Asn Glu Ala 
        115                 120                 125             


Lys Asp Val Glu Arg Glu Val Cys Phe Ile Asp Ile Ala Cys Asp Glu 
    130                 135                 140                 


Ile Pro Glu Arg Tyr Tyr Lys Glu Ser Glu Asp Pro Lys His Phe Lys 
145                 150                 155                 160 


Ser Glu Lys Thr Gly Arg Gly Gln Leu Arg Glu Gly Trp Arg Asp Ser 
                165                 170                 175     


His Gln Pro Ile Met Cys Ser Tyr Lys Leu Val Thr Val Lys Phe Glu 
            180                 185                 190         


Val Trp Gly Leu Gln Thr Arg Val Glu Gln Phe Val His Lys Val Val 
        195                 200                 205             


Arg Asp Ile Leu Leu Ile Gly His Arg Gln Ala Phe Ala Trp Val Asp 
    210                 215                 220                 


Glu Trp Tyr Asp Met Thr Met Asp Asp Val Arg Glu Tyr Glu Lys Asn 
225                 230                 235                 240 


Met His Glu Gln Thr Asn Ile Lys Val Cys Asn Gln His Ser Ser Pro 
                245                 250                 255     


Val Asp Asp Ile Glu Ser His Ala Gln Thr Ser Thr 
            260                 265             


<210>  4082
<211>  119
<212>  PRT
<213>  homo sapiens

<400>  4082

Met Val Arg Ile Ser Lys Pro Lys Thr Phe Gln Ala Tyr Leu Asp Asp 
1               5                   10                  15      


Cys His Arg Arg Tyr Ser Cys Ala His Cys Arg Ala His Leu Ala Asn 
            20                  25                  30          


His Asp Asp Leu Ile Ser Lys Ser Phe Gln Gly Ser Gln Gly Arg Ala 
        35                  40                  45              


Tyr Leu Phe Asn Ser Val Val Asn Val Gly Cys Gly Pro Ala Glu Glu 
    50                  55                  60                  


Arg Val Leu Leu Thr Gly Leu His Ala Val Ala Asp Ile His Cys Glu 
65                  70                  75                  80  


Asn Cys Lys Thr Thr Leu Gly Trp Lys Tyr Glu Gln Ala Phe Glu Ser 
                85                  90                  95      


Ser Gln Lys Tyr Lys Glu Gly Lys Tyr Ile Ile Glu Leu Asn His Met 
            100                 105                 110         


Ile Lys Asp Asn Gly Trp Asp 
        115                 


<210>  4083
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  4083

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  4084
<211>  1332
<212>  PRT
<213>  homo sapiens

<400>  4084

Met Gln Gln Ala Pro Gln Pro Tyr Glu Phe Phe Ser Glu Glu Asn Ser 
1               5                   10                  15      


Pro Lys Trp Arg Gly Leu Leu Val Ser Ala Leu Arg Lys Val Gln Glu 
            20                  25                  30          


Gln Val His Pro Thr Leu Ser Ala Asn Glu Glu Ser Leu Tyr Tyr Ile 
        35                  40                  45              


Glu Glu Leu Ile Phe Gln Leu Leu Asn Lys Leu Cys Met Ala Gln Pro 
    50                  55                  60                  


Arg Thr Val Gln Asp Val Glu Glu Arg Val Gln Lys Thr Phe Pro His 
65                  70                  75                  80  


Pro Ile Asp Lys Trp Ala Ile Ala Asp Ala Gln Ser Ala Ile Glu Lys 
                85                  90                  95      


Arg Lys Arg Arg Asn Pro Leu Leu Leu Pro Val Asp Lys Ile His Pro 
            100                 105                 110         


Ser Leu Lys Glu Val Leu Gly Tyr Lys Val Asp Tyr His Val Ser Leu 
        115                 120                 125             


Tyr Ile Val Ala Val Leu Glu Tyr Ile Ser Ala Asp Ile Leu Lys Leu 
    130                 135                 140                 


Ala Gly Asn Tyr Val Phe Asn Ile Arg His Tyr Glu Ile Ser Gln Gln 
145                 150                 155                 160 


Asp Ile Lys Val Ser Met Cys Ala Asp Lys Val Leu Met Asp Met Phe 
                165                 170                 175     


Asp Gln Asp Asp Ile Gly Leu Val Ser Leu Cys Glu Asp Glu Pro Ser 
            180                 185                 190         


Ser Ser Gly Glu Leu Asn Tyr Tyr Asp Leu Val Arg Thr Glu Ile Ala 
        195                 200                 205             


Glu Glu Arg Gln Tyr Leu Arg Glu Leu Asn Met Ile Ile Lys Val Phe 
    210                 215                 220                 


Arg Glu Ala Phe Leu Ser Asp Arg Lys Leu Phe Lys Pro Ser Asp Ile 
225                 230                 235                 240 


Glu Lys Ile Phe Ser Asn Ile Ser Asp Ile His Glu Leu Thr Val Lys 
                245                 250                 255     


Leu Leu Gly Leu Ile Glu Asp Thr Val Glu Met Thr Asp Glu Ser Ser 
            260                 265                 270         


Pro His Pro Leu Ala Gly Ser Cys Phe Glu Asp Leu Ala Glu Glu Gln 
        275                 280                 285             


Ala Phe Asp Pro Tyr Glu Thr Leu Ser Gln Asp Ile Leu Ser Pro Glu 
    290                 295                 300                 


Phe His Glu His Phe Asn Lys Leu Met Ala Arg Pro Ala Val Ala Leu 
305                 310                 315                 320 


His Phe Gln Ser Ile Ala Asp Gly Phe Lys Glu Ala Val Arg Tyr Val 
                325                 330                 335     


Leu Pro Arg Leu Met Leu Val Pro Val Tyr His Cys Trp His Tyr Phe 
            340                 345                 350         


Glu Leu Leu Lys Gln Leu Lys Ala Cys Ser Glu Glu Gln Glu Asp Arg 
        355                 360                 365             


Glu Cys Leu Asn Gln Ala Ile Thr Ala Leu Met Asn Leu Gln Gly Ser 
    370                 375                 380                 


Met Asp Arg Ile Tyr Lys Gln Tyr Ser Pro Arg Arg Arg Pro Gly Asp 
385                 390                 395                 400 


Pro Val Cys Pro Phe Tyr Ser His Gln Leu Arg Ser Lys His Leu Ala 
                405                 410                 415     


Ile Lys Lys Met Asn Glu Ile Gln Lys Asn Ile Asp Gly Trp Glu Gly 
            420                 425                 430         


Lys Asp Ile Gly Gln Cys Cys Asn Glu Phe Ile Met Glu Gly Pro Leu 
        435                 440                 445             


Thr Arg Ile Gly Ala Lys His Glu Arg His Ile Phe Leu Phe Asp Gly 
    450                 455                 460                 


Leu Met Ile Ser Cys Lys Pro Asn His Gly Gln Thr Arg Leu Pro Gly 
465                 470                 475                 480 


Tyr Ser Ser Ala Glu Tyr Arg Leu Lys Glu Lys Phe Val Met Arg Lys 
                485                 490                 495     


Ile Gln Ile Cys Asp Lys Glu Asp Thr Cys Glu His Lys His Ala Phe 
            500                 505                 510         


Glu Leu Val Ser Lys Asp Glu Asn Ser Ile Ile Phe Ala Ala Lys Ser 
        515                 520                 525             


Ala Glu Glu Lys Asn Asn Trp Met Ala Ala Leu Ile Ser Leu His Tyr 
    530                 535                 540                 


Arg Ser Thr Leu Asp Arg Met Leu Asp Ser Val Leu Leu Lys Glu Glu 
545                 550                 555                 560 


Asn Glu Gln Pro Leu Arg Leu Pro Ser Pro Glu Val Tyr Arg Phe Val 
                565                 570                 575     


Val Lys Asp Ser Glu Glu Asn Ile Val Phe Glu Asp Asn Leu Gln Ser 
            580                 585                 590         


Arg Ser Gly Ile Pro Ile Ile Lys Gly Gly Thr Val Val Lys Leu Ile 
        595                 600                 605             


Glu Arg Leu Thr Tyr His Met Tyr Ala Asp Pro Asn Phe Val Arg Thr 
    610                 615                 620                 


Phe Leu Thr Thr Tyr Arg Ser Phe Cys Lys Pro Gln Glu Leu Leu Ser 
625                 630                 635                 640 


Leu Leu Ile Glu Arg Phe Glu Ile Pro Glu Pro Glu Pro Thr Asp Ala 
                645                 650                 655     


Asp Lys Leu Ala Ile Glu Lys Gly Glu Gln Pro Ile Ser Ala Asp Leu 
            660                 665                 670         


Lys Arg Phe Arg Lys Glu Tyr Val Gln Pro Val Gln Leu Arg Ile Leu 
        675                 680                 685             


Asn Val Phe Arg His Trp Val Glu His His Phe Tyr Asp Phe Glu Arg 
    690                 695                 700                 


Asp Leu Glu Leu Leu Glu Arg Leu Glu Ser Phe Ile Ser Ser Val Arg 
705                 710                 715                 720 


Gly Lys Ala Met Lys Lys Trp Val Glu Ser Ile Ala Lys Ile Ile Arg 
                725                 730                 735     


Arg Lys Lys Gln Ala Gln Ala Asn Gly Val Ser His Asn Ile Thr Phe 
            740                 745                 750         


Glu Ser Pro Pro Pro Pro Ile Glu Trp His Ile Ser Lys Pro Gly Gln 
        755                 760                 765             


Phe Glu Thr Phe Asp Leu Met Thr Leu His Pro Ile Glu Ile Ala Arg 
    770                 775                 780                 


Gln Leu Thr Leu Leu Glu Ser Asp Leu Tyr Arg Lys Val Gln Pro Ser 
785                 790                 795                 800 


Glu Leu Val Gly Ser Val Trp Thr Lys Glu Asp Lys Glu Ile Asn Ser 
                805                 810                 815     


Pro Asn Leu Leu Lys Met Ile Arg His Thr Thr Asn Leu Thr Leu Trp 
            820                 825                 830         


Phe Glu Lys Cys Ile Val Glu Ala Glu Asn Phe Glu Glu Arg Val Ala 
        835                 840                 845             


Val Leu Ser Arg Ile Ile Glu Ile Leu Gln Val Phe Gln Asp Leu Asn 
    850                 855                 860                 


Asn Phe Asn Gly Val Leu Glu Ile Val Ser Ala Val Asn Ser Val Ser 
865                 870                 875                 880 


Val Tyr Arg Leu Asp His Thr Phe Glu Ala Leu Gln Glu Arg Lys Arg 
                885                 890                 895     


Lys Ile Leu Asp Glu Ala Val Glu Leu Ser Gln Asp His Phe Lys Lys 
            900                 905                 910         


Tyr Leu Val Lys Leu Lys Ser Ile Asn Pro Pro Cys Val Pro Phe Phe 
        915                 920                 925             


Gly Ile Tyr Leu Thr Asn Ile Leu Lys Thr Glu Glu Gly Asn Asn Asp 
    930                 935                 940                 


Phe Leu Lys Lys Lys Gly Lys Asp Leu Ile Asn Phe Ser Lys Arg Arg 
945                 950                 955                 960 


Lys Val Ala Glu Ile Thr Gly Glu Ile Gln Gln Tyr Gln Asn Gln Pro 
                965                 970                 975     


Tyr Cys Leu Arg Ile Glu Pro Asp Met Arg Arg Phe Phe Glu Asn Leu 
            980                 985                 990         


Asn Pro Met Gly Ser Ala Ser Glu  Lys Glu Phe Thr Asp  Tyr Leu Phe 
        995                 1000                 1005             


Asn Lys  Ser Leu Glu Ile Glu  Pro Arg Asn Cys Lys  Gln Pro Pro 
    1010                 1015                 1020             


Arg Phe  Pro Arg Lys Ser Thr  Phe Ser Leu Lys Ser  Pro Gly Ile 
    1025                 1030                 1035             


Arg Pro  Asn Thr Gly Arg His  Gly Ser Thr Ser Gly  Thr Leu Arg 
    1040                 1045                 1050             


Gly His  Pro Thr Pro Leu Glu  Arg Glu Pro Cys Lys  Ile Ser Phe 
    1055                 1060                 1065             


Ser Arg  Ile Ala Glu Thr Glu  Leu Glu Ser Thr Val  Ser Ala Pro 
    1070                 1075                 1080             


Thr Ser  Pro Asn Thr Pro Ser  Thr Pro Pro Val Ser  Ala Ser Ser 
    1085                 1090                 1095             


Asp Leu  Ser Val Phe Leu Asp  Val Asp Leu Asn Ser  Ser Cys Gly 
    1100                 1105                 1110             


Ser Asn  Ser Ile Phe Ala Pro  Val Leu Leu Pro His  Ser Lys Ser 
    1115                 1120                 1125             


Phe Phe  Ser Ser Cys Gly Ser  Leu His Lys Leu Ser  Glu Glu Pro 
    1130                 1135                 1140             


Leu Ile  Pro Pro Pro Leu Pro  Pro Arg Lys Lys Phe  Asp His Asp 
    1145                 1150                 1155             


Ala Ser  Asn Ser Lys Gly Asn  Met Lys Ser Asp Asp  Asp Pro Pro 
    1160                 1165                 1170             


Ala Ile  Pro Pro Arg Gln Pro  Pro Pro Pro Lys Val  Lys Pro Arg 
    1175                 1180                 1185             


Val Pro  Val Pro Thr Gly Ala  Phe Asp Gly Pro Leu  His Ser Pro 
    1190                 1195                 1200             


Pro Pro  Pro Pro Pro Arg Asp  Pro Leu Pro Asp Thr  Pro Pro Pro 
    1205                 1210                 1215             


Val Pro  Leu Arg Pro Pro Glu  His Phe Ile Asn Cys  Pro Phe Asn 
    1220                 1225                 1230             


Leu Gln  Pro Pro Pro Leu Gly  His Leu His Arg Asp  Ser Asp Trp 
    1235                 1240                 1245             


Leu Arg  Asp Ile Ser Thr Cys  Pro Asn Ser Pro Ser  Thr Pro Pro 
    1250                 1255                 1260             


Ser Thr  Pro Ser Pro Arg Val  Pro Arg Arg Cys Tyr  Val Leu Ser 
    1265                 1270                 1275             


Ser Ser  Gln Asn Asn Leu Ala  His Pro Pro Ala Pro  Pro Val Pro 
    1280                 1285                 1290             


Pro Arg  Gln Asn Ser Ser Pro  His Leu Pro Lys Leu  Pro Pro Lys 
    1295                 1300                 1305             


Thr Tyr  Lys Arg Glu Leu Ser  His Pro Pro Leu Tyr  Arg Leu Pro 
    1310                 1315                 1320             


Leu Leu  Glu Asn Ala Glu Thr  Pro Gln 
    1325                 1330         


<210>  4085
<211>  93
<212>  PRT
<213>  homo sapiens

<400>  4085

Met Ser Gly Leu Arg Val Tyr Ser Thr Ser Val Thr Gly Ser Arg Glu 
1               5                   10                  15      


Ile Lys Ser Gln Gln Ser Glu Val Thr Arg Ile Leu Asp Gly Lys Arg 
            20                  25                  30          


Ile Gln Tyr Gln Leu Val Asp Ile Ser Gln Asp Asn Ala Leu Arg Asp 
        35                  40                  45              


Glu Met Arg Ala Leu Ala Gly Asn Pro Lys Ala Thr Pro Pro Gln Ile 
    50                  55                  60                  


Val Asn Gly Asp Gln Tyr Cys Gly Asp Tyr Glu Leu Phe Val Glu Ala 
65                  70                  75                  80  


Val Glu Gln Asn Thr Leu Gln Glu Phe Leu Lys Leu Ala 
                85                  90              


<210>  4086
<211>  1669
<212>  PRT
<213>  homo sapiens

<400>  4086

Met Gly Pro Arg Leu Ser Val Trp Leu Leu Leu Leu Pro Ala Ala Leu 
1               5                   10                  15      


Leu Leu His Glu Glu His Ser Arg Ala Ala Ala Lys Gly Gly Cys Ala 
            20                  25                  30          


Gly Ser Gly Cys Gly Lys Cys Asp Cys His Gly Val Lys Gly Gln Lys 
        35                  40                  45              


Gly Glu Arg Gly Leu Pro Gly Leu Gln Gly Val Ile Gly Phe Pro Gly 
    50                  55                  60                  


Met Gln Gly Pro Glu Gly Pro Gln Gly Pro Pro Gly Gln Lys Gly Asp 
65                  70                  75                  80  


Thr Gly Glu Pro Gly Leu Pro Gly Thr Lys Gly Thr Arg Gly Pro Pro 
                85                  90                  95      


Gly Ala Ser Gly Tyr Pro Gly Asn Pro Gly Leu Pro Gly Ile Pro Gly 
            100                 105                 110         


Gln Asp Gly Pro Pro Gly Pro Pro Gly Ile Pro Gly Cys Asn Gly Thr 
        115                 120                 125             


Lys Gly Glu Arg Gly Pro Leu Gly Pro Pro Gly Leu Pro Gly Phe Ala 
    130                 135                 140                 


Gly Asn Pro Gly Pro Pro Gly Leu Pro Gly Met Lys Gly Asp Pro Gly 
145                 150                 155                 160 


Glu Ile Leu Gly His Val Pro Gly Met Leu Leu Lys Gly Glu Arg Gly 
                165                 170                 175     


Phe Pro Gly Ile Pro Gly Thr Pro Gly Pro Pro Gly Leu Pro Gly Leu 
            180                 185                 190         


Gln Gly Pro Val Gly Pro Pro Gly Phe Thr Gly Pro Pro Gly Pro Pro 
        195                 200                 205             


Gly Pro Pro Gly Pro Pro Gly Glu Lys Gly Gln Met Gly Leu Ser Phe 
    210                 215                 220                 


Gln Gly Pro Lys Gly Asp Lys Gly Asp Gln Gly Val Ser Gly Pro Pro 
225                 230                 235                 240 


Gly Val Pro Gly Gln Ala Gln Val Gln Glu Lys Gly Asp Phe Ala Thr 
                245                 250                 255     


Lys Gly Glu Lys Gly Gln Lys Gly Glu Pro Gly Phe Gln Gly Met Pro 
            260                 265                 270         


Gly Val Gly Glu Lys Gly Glu Pro Gly Lys Pro Gly Pro Arg Gly Lys 
        275                 280                 285             


Pro Gly Lys Asp Gly Asp Lys Gly Glu Lys Gly Ser Pro Gly Phe Pro 
    290                 295                 300                 


Gly Glu Pro Gly Tyr Pro Gly Leu Ile Gly Arg Gln Gly Pro Gln Gly 
305                 310                 315                 320 


Glu Lys Gly Glu Ala Gly Pro Pro Gly Pro Pro Gly Ile Val Ile Gly 
                325                 330                 335     


Thr Gly Pro Leu Gly Glu Lys Gly Glu Arg Gly Tyr Pro Gly Thr Pro 
            340                 345                 350         


Gly Pro Arg Gly Glu Pro Gly Pro Lys Gly Phe Pro Gly Leu Pro Gly 
        355                 360                 365             


Gln Pro Gly Pro Pro Gly Leu Pro Val Pro Gly Gln Ala Gly Ala Pro 
    370                 375                 380                 


Gly Phe Pro Gly Glu Arg Gly Glu Lys Gly Asp Arg Gly Phe Pro Gly 
385                 390                 395                 400 


Thr Ser Leu Pro Gly Pro Ser Gly Arg Asp Gly Leu Pro Gly Pro Pro 
                405                 410                 415     


Gly Ser Pro Gly Pro Pro Gly Gln Pro Gly Tyr Thr Asn Gly Ile Val 
            420                 425                 430         


Glu Cys Gln Pro Gly Pro Pro Gly Asp Gln Gly Pro Pro Gly Ile Pro 
        435                 440                 445             


Gly Gln Pro Gly Phe Ile Gly Glu Ile Gly Glu Lys Gly Gln Lys Gly 
    450                 455                 460                 


Glu Ser Cys Leu Ile Cys Asp Ile Asp Gly Tyr Arg Gly Pro Pro Gly 
465                 470                 475                 480 


Pro Gln Gly Pro Pro Gly Glu Ile Gly Phe Pro Gly Gln Pro Gly Ala 
                485                 490                 495     


Lys Gly Asp Arg Gly Leu Pro Gly Arg Asp Gly Val Ala Gly Val Pro 
            500                 505                 510         


Gly Pro Gln Gly Thr Pro Gly Leu Ile Gly Gln Pro Gly Ala Lys Gly 
        515                 520                 525             


Glu Pro Gly Glu Phe Tyr Phe Asp Leu Arg Leu Lys Gly Asp Lys Gly 
    530                 535                 540                 


Asp Pro Gly Phe Pro Gly Gln Pro Gly Met Pro Gly Arg Ala Gly Ser 
545                 550                 555                 560 


Pro Gly Arg Asp Gly His Pro Gly Leu Pro Gly Pro Lys Gly Ser Pro 
                565                 570                 575     


Gly Ser Val Gly Leu Lys Gly Glu Arg Gly Pro Pro Gly Gly Val Gly 
            580                 585                 590         


Phe Pro Gly Ser Arg Gly Asp Thr Gly Pro Pro Gly Pro Pro Gly Tyr 
        595                 600                 605             


Gly Pro Ala Gly Pro Ile Gly Asp Lys Gly Gln Ala Gly Phe Pro Gly 
    610                 615                 620                 


Gly Pro Gly Ser Pro Gly Leu Pro Gly Pro Lys Gly Glu Pro Gly Lys 
625                 630                 635                 640 


Ile Val Pro Leu Pro Gly Pro Pro Gly Ala Glu Gly Leu Pro Gly Ser 
                645                 650                 655     


Pro Gly Phe Pro Gly Pro Gln Gly Asp Arg Gly Phe Pro Gly Thr Pro 
            660                 665                 670         


Gly Arg Pro Gly Leu Pro Gly Glu Lys Gly Ala Val Gly Gln Pro Gly 
        675                 680                 685             


Ile Gly Phe Pro Gly Pro Pro Gly Pro Lys Gly Val Asp Gly Leu Pro 
    690                 695                 700                 


Gly Asp Met Gly Pro Pro Gly Thr Pro Gly Arg Pro Gly Phe Asn Gly 
705                 710                 715                 720 


Leu Pro Gly Asn Pro Gly Val Gln Gly Gln Lys Gly Glu Pro Gly Val 
                725                 730                 735     


Gly Leu Pro Gly Leu Lys Gly Leu Pro Gly Leu Pro Gly Ile Pro Gly 
            740                 745                 750         


Thr Pro Gly Glu Lys Gly Ser Ile Gly Val Pro Gly Val Pro Gly Glu 
        755                 760                 765             


His Gly Ala Ile Gly Pro Pro Gly Leu Gln Gly Ile Arg Gly Glu Pro 
    770                 775                 780                 


Gly Pro Pro Gly Leu Pro Gly Ser Val Gly Ser Pro Gly Val Pro Gly 
785                 790                 795                 800 


Ile Gly Pro Pro Gly Ala Arg Gly Pro Pro Gly Gly Gln Gly Pro Pro 
                805                 810                 815     


Gly Leu Ser Gly Pro Pro Gly Ile Lys Gly Glu Lys Gly Phe Pro Gly 
            820                 825                 830         


Phe Pro Gly Leu Asp Met Pro Gly Pro Lys Gly Asp Lys Gly Ala Gln 
        835                 840                 845             


Gly Leu Pro Gly Ile Thr Gly Gln Ser Gly Leu Pro Gly Leu Pro Gly 
    850                 855                 860                 


Gln Gln Gly Ala Pro Gly Ile Pro Gly Phe Pro Gly Ser Lys Gly Glu 
865                 870                 875                 880 


Met Gly Val Met Gly Thr Pro Gly Gln Pro Gly Ser Pro Gly Pro Val 
                885                 890                 895     


Gly Ala Pro Gly Leu Pro Gly Glu Lys Gly Asp His Gly Phe Pro Gly 
            900                 905                 910         


Ser Ser Gly Pro Arg Gly Asp Pro Gly Leu Lys Gly Asp Lys Gly Asp 
        915                 920                 925             


Val Gly Leu Pro Gly Lys Pro Gly Ser Met Asp Lys Val Asp Met Gly 
    930                 935                 940                 


Ser Met Lys Gly Gln Lys Gly Asp Gln Gly Glu Lys Gly Gln Ile Gly 
945                 950                 955                 960 


Pro Ile Gly Glu Lys Gly Ser Arg Gly Asp Pro Gly Thr Pro Gly Val 
                965                 970                 975     


Pro Gly Lys Asp Gly Gln Ala Gly Gln Pro Gly Gln Pro Gly Pro Lys 
            980                 985                 990         


Gly Asp Pro Gly Ile Ser Gly Thr  Pro Gly Ala Pro Gly  Leu Pro Gly 
        995                 1000                 1005             


Pro Lys  Gly Ser Val Gly Gly  Met Gly Leu Pro Gly  Thr Pro Gly 
    1010                 1015                 1020             


Glu Lys  Gly Val Pro Gly Ile  Pro Gly Pro Gln Gly  Ser Pro Gly 
    1025                 1030                 1035             


Leu Pro  Gly Asp Lys Gly Ala  Lys Gly Glu Lys Gly  Gln Ala Gly 
    1040                 1045                 1050             


Pro Pro  Gly Ile Gly Ile Pro  Gly Leu Arg Gly Glu  Lys Gly Asp 
    1055                 1060                 1065             


Gln Gly  Ile Ala Gly Phe Pro  Gly Ser Pro Gly Glu  Lys Gly Glu 
    1070                 1075                 1080             


Lys Gly  Ser Ile Gly Ile Pro  Gly Met Pro Gly Ser  Pro Gly Leu 
    1085                 1090                 1095             


Lys Gly  Ser Pro Gly Ser Val  Gly Tyr Pro Gly Ser  Pro Gly Leu 
    1100                 1105                 1110             


Pro Gly  Glu Lys Gly Asp Lys  Gly Leu Pro Gly Leu  Asp Gly Ile 
    1115                 1120                 1125             


Pro Gly  Val Lys Gly Glu Ala  Gly Leu Pro Gly Thr  Pro Gly Pro 
    1130                 1135                 1140             


Thr Gly  Pro Ala Gly Gln Lys  Gly Glu Pro Gly Ser  Asp Gly Ile 
    1145                 1150                 1155             


Pro Gly  Ser Ala Gly Glu Lys  Gly Glu Pro Gly Leu  Pro Gly Arg 
    1160                 1165                 1170             


Gly Phe  Pro Gly Phe Pro Gly  Ala Lys Gly Asp Lys  Gly Ser Lys 
    1175                 1180                 1185             


Gly Glu  Val Gly Phe Pro Gly  Leu Ala Gly Ser Pro  Gly Ile Pro 
    1190                 1195                 1200             


Gly Ser  Lys Gly Glu Gln Gly  Phe Met Gly Pro Pro  Gly Pro Gln 
    1205                 1210                 1215             


Gly Gln  Pro Gly Leu Pro Gly  Ser Pro Gly His Ala  Thr Glu Gly 
    1220                 1225                 1230             


Pro Lys  Gly Asp Arg Gly Pro  Gln Gly Gln Pro Gly  Leu Pro Gly 
    1235                 1240                 1245             


Leu Pro  Gly Pro Met Gly Pro  Pro Gly Leu Pro Gly  Ile Asp Gly 
    1250                 1255                 1260             


Val Lys  Gly Asp Lys Gly Asn  Pro Gly Trp Pro Gly  Ala Pro Gly 
    1265                 1270                 1275             


Val Pro  Gly Pro Lys Gly Asp  Pro Gly Phe Gln Gly  Met Pro Gly 
    1280                 1285                 1290             


Ile Gly  Gly Ser Pro Gly Ile  Thr Gly Ser Lys Gly  Asp Met Gly 
    1295                 1300                 1305             


Pro Pro  Gly Val Pro Gly Phe  Gln Gly Pro Lys Gly  Leu Pro Gly 
    1310                 1315                 1320             


Leu Gln  Gly Ile Lys Gly Asp  Gln Gly Asp Gln Gly  Val Pro Gly 
    1325                 1330                 1335             


Ala Lys  Gly Leu Pro Gly Pro  Pro Gly Pro Pro Gly  Pro Tyr Asp 
    1340                 1345                 1350             


Ile Ile  Lys Gly Glu Pro Gly  Leu Pro Gly Pro Glu  Gly Pro Pro 
    1355                 1360                 1365             


Gly Leu  Lys Gly Leu Gln Gly  Leu Pro Gly Pro Lys  Gly Gln Gln 
    1370                 1375                 1380             


Gly Val  Thr Gly Leu Val Gly  Ile Pro Gly Pro Pro  Gly Ile Pro 
    1385                 1390                 1395             


Gly Phe  Asp Gly Ala Pro Gly  Gln Lys Gly Glu Met  Gly Pro Ala 
    1400                 1405                 1410             


Gly Pro  Thr Gly Pro Arg Gly  Phe Pro Gly Pro Pro  Gly Pro Asp 
    1415                 1420                 1425             


Gly Leu  Pro Gly Ser Met Gly  Pro Pro Gly Thr Pro  Ser Val Asp 
    1430                 1435                 1440             


His Gly  Phe Leu Val Thr Arg  His Ser Gln Thr Ile  Asp Asp Pro 
    1445                 1450                 1455             


Gln Cys  Pro Ser Gly Thr Lys  Ile Leu Tyr His Gly  Tyr Ser Leu 
    1460                 1465                 1470             


Leu Tyr  Val Gln Gly Asn Glu  Arg Ala His Gly Gln  Asp Leu Gly 
    1475                 1480                 1485             


Thr Ala  Gly Ser Cys Leu Arg  Lys Phe Ser Thr Met  Pro Phe Leu 
    1490                 1495                 1500             


Phe Cys  Asn Ile Asn Asn Val  Cys Asn Phe Ala Ser  Arg Asn Asp 
    1505                 1510                 1515             


Tyr Ser  Tyr Trp Leu Ser Thr  Pro Glu Pro Met Pro  Met Ser Met 
    1520                 1525                 1530             


Ala Pro  Ile Thr Gly Glu Asn  Ile Arg Pro Phe Ile  Ser Arg Cys 
    1535                 1540                 1545             


Ala Val  Cys Glu Ala Pro Ala  Met Val Met Ala Val  His Ser Gln 
    1550                 1555                 1560             


Thr Ile  Gln Ile Pro Pro Cys  Pro Ser Gly Trp Ser  Ser Leu Trp 
    1565                 1570                 1575             


Ile Gly  Tyr Ser Phe Val Met  His Thr Ser Ala Gly  Ala Glu Gly 
    1580                 1585                 1590             


Ser Gly  Gln Ala Leu Ala Ser  Pro Gly Ser Cys Leu  Glu Glu Phe 
    1595                 1600                 1605             


Arg Ser  Ala Pro Phe Ile Glu  Cys His Gly Arg Gly  Thr Cys Asn 
    1610                 1615                 1620             


Tyr Tyr  Ala Asn Ala Tyr Ser  Phe Trp Leu Ala Thr  Ile Glu Arg 
    1625                 1630                 1635             


Ser Glu  Met Phe Lys Lys Pro  Thr Pro Ser Thr Leu  Lys Ala Gly 
    1640                 1645                 1650             


Glu Leu  Arg Thr His Val Ser  Arg Cys Gln Val Cys  Met Arg Arg 
    1655                 1660                 1665             


Thr 
    


<210>  4087
<211>  180
<212>  PRT
<213>  homo sapiens

<400>  4087

Met Ala Ala Ala Glu Glu Glu Asp Gly Gly Pro Glu Gly Pro Asn Arg 
1               5                   10                  15      


Glu Arg Gly Gly Ala Gly Ala Thr Phe Glu Cys Asn Ile Cys Leu Glu 
            20                  25                  30          


Thr Ala Arg Glu Ala Val Val Ser Val Cys Gly His Leu Tyr Cys Trp 
        35                  40                  45              


Pro Cys Leu His Gln Trp Leu Glu Thr Arg Pro Glu Arg Gln Glu Cys 
    50                  55                  60                  


Pro Val Cys Lys Ala Gly Ile Ser Arg Glu Lys Val Val Pro Leu Tyr 
65                  70                  75                  80  


Gly Arg Gly Ser Gln Lys Pro Gln Asp Pro Arg Leu Lys Thr Pro Pro 
                85                  90                  95      


Arg Pro Gln Gly Gln Arg Pro Ala Pro Glu Ser Arg Gly Gly Phe Gln 
            100                 105                 110         


Pro Phe Gly Asp Thr Gly Gly Phe His Phe Ser Phe Gly Val Gly Ala 
        115                 120                 125             


Phe Pro Phe Gly Phe Phe Thr Thr Val Phe Asn Ala His Glu Pro Phe 
    130                 135                 140                 


Arg Arg Gly Thr Gly Val Asp Leu Gly Gln Gly His Pro Ala Ser Ser 
145                 150                 155                 160 


Trp Gln Asp Ser Leu Phe Leu Phe Leu Ala Ile Phe Phe Phe Phe Trp 
                165                 170                 175     


Leu Leu Ser Ile 
            180 


<210>  4088
<211>  685
<212>  PRT
<213>  homo sapiens

<400>  4088

Met Asn Gln Ser Arg Ser Arg Ser Asp Gly Gly Ser Glu Glu Thr Leu 
1               5                   10                  15      


Pro Gln Asp His Asn His His Glu Asn Glu Arg Arg Trp Gln Gln Glu 
            20                  25                  30          


Arg Leu His Arg Glu Glu Ala Tyr Tyr Gln Phe Ile Asn Glu Leu Asn 
        35                  40                  45              


Asp Glu Asp Tyr Arg Leu Met Arg Asp His Asn Leu Leu Gly Thr Pro 
    50                  55                  60                  


Gly Glu Ile Thr Ser Glu Glu Leu Gln Gln Arg Leu Asp Gly Val Lys 
65                  70                  75                  80  


Glu Gln Leu Ala Ser Gln Pro Asp Leu Arg Asp Gly Thr Asn Tyr Arg 
                85                  90                  95      


Asp Ser Glu Val Pro Arg Glu Ser Ser His Glu Asp Ser Leu Leu Glu 
            100                 105                 110         


Trp Leu Asn Thr Phe Arg Arg Thr Gly Asn Ala Thr Arg Ser Gly Gln 
        115                 120                 125             


Asn Gly Asn Gln Thr Trp Arg Ala Val Ser Arg Thr Asn Pro Asn Asn 
    130                 135                 140                 


Gly Glu Phe Arg Phe Ser Leu Glu Ile His Val Asn His Glu Asn Arg 
145                 150                 155                 160 


Gly Phe Glu Ile His Gly Glu Asp Tyr Thr Asp Ile Pro Leu Ser Asp 
                165                 170                 175     


Ser Asn Arg Asp His Thr Ala Asn Arg Gln Gln Arg Ser Thr Ser Pro 
            180                 185                 190         


Val Ala Arg Arg Thr Arg Ser Gln Thr Ser Val Asn Phe Asn Gly Ser 
        195                 200                 205             


Ser Ser Asn Ile Pro Arg Thr Arg Leu Ala Ser Arg Gly Gln Asn Pro 
    210                 215                 220                 


Ala Glu Gly Ser Phe Ser Thr Leu Gly Arg Leu Arg Asn Gly Ile Gly 
225                 230                 235                 240 


Gly Ala Ala Gly Ile Pro Arg Ala Asn Ala Ser Arg Thr Asn Phe Ser 
                245                 250                 255     


Ser His Thr Asn Gln Ser Gly Gly Ser Glu Leu Arg Gln Arg Glu Gly 
            260                 265                 270         


Gln Arg Phe Gly Ala Ala His Val Trp Glu Asn Gly Ala Arg Ser Asn 
        275                 280                 285             


Val Thr Val Arg Asn Thr Asn Gln Arg Leu Glu Pro Ile Arg Leu Arg 
    290                 295                 300                 


Ser Thr Ser Asn Ser Arg Ser Arg Ser Pro Ile Gln Arg Gln Ser Gly 
305                 310                 315                 320 


Thr Val Tyr His Asn Ser Gln Arg Glu Ser Arg Pro Val Gln Gln Thr 
                325                 330                 335     


Thr Arg Arg Ser Val Arg Arg Arg Gly Arg Thr Arg Val Phe Leu Glu 
            340                 345                 350         


Gln Asp Arg Glu Arg Glu Arg Arg Gly Thr Ala Tyr Thr Pro Phe Ser 
        355                 360                 365             


Asn Ser Arg Leu Val Ser Arg Ile Thr Val Glu Glu Gly Glu Glu Ser 
    370                 375                 380                 


Ser Arg Ser Ser Thr Ala Val Arg Arg His Pro Thr Ile Thr Leu Asp 
385                 390                 395                 400 


Leu Gln Val Arg Arg Ile Arg Pro Gly Glu Asn Arg Asp Arg Asp Ser 
                405                 410                 415     


Ile Ala Asn Arg Thr Arg Ser Arg Val Gly Leu Ala Glu Asn Thr Val 
            420                 425                 430         


Thr Ile Glu Ser Asn Ser Gly Gly Phe Arg Arg Thr Ile Ser Arg Leu 
        435                 440                 445             


Glu Arg Ser Gly Ile Arg Thr Tyr Val Ser Thr Ile Thr Val Pro Leu 
    450                 455                 460                 


Arg Arg Ile Ser Glu Asn Glu Leu Val Glu Pro Ser Ser Val Ala Leu 
465                 470                 475                 480 


Arg Ser Ile Leu Arg Gln Ile Met Thr Gly Phe Gly Glu Leu Ser Ser 
                485                 490                 495     


Leu Met Glu Ala Asp Ser Glu Ser Glu Leu Gln Arg Asn Gly Gln His 
            500                 505                 510         


Leu Pro Asp Met His Ser Glu Leu Ser Asn Leu Gly Thr Asp Asn Asn 
        515                 520                 525             


Arg Ser Gln His Arg Glu Gly Ser Ser Gln Asp Arg Gln Ala Gln Gly 
    530                 535                 540                 


Asp Ser Thr Glu Met His Gly Glu Asn Glu Thr Thr Gln Pro His Thr 
545                 550                 555                 560 


Arg Asn Ser Asp Ser Arg Gly Gly Arg Gln Leu Arg Asn Pro Asn Asn 
                565                 570                 575     


Leu Val Glu Thr Gly Thr Leu Pro Ile Leu Arg Leu Ala His Phe Phe 
            580                 585                 590         


Leu Leu Asn Glu Ser Asp Asp Asp Asp Arg Ile Arg Gly Leu Thr Lys 
        595                 600                 605             


Glu Gln Ile Asp Asn Leu Ser Thr Arg His Tyr Glu His Asn Ser Ile 
    610                 615                 620                 


Asp Ser Glu Leu Gly Lys Ile Cys Ser Val Cys Ile Ser Asp Tyr Val 
625                 630                 635                 640 


Thr Gly Asn Lys Leu Arg Gln Leu Pro Cys Met His Glu Phe His Ile 
                645                 650                 655     


His Cys Ile Asp Arg Trp Leu Ser Glu Asn Cys Thr Cys Pro Ile Cys 
            660                 665                 670         


Arg Gln Pro Val Leu Gly Ser Asn Ile Ala Asn Asn Gly 
        675                 680                 685 


<210>  4089
<211>  565
<212>  PRT
<213>  homo sapiens

<400>  4089

Met Gly Gln Thr Ser Val Ser Thr Leu Ser Pro Gln Pro Gly Ser Val 
1               5                   10                  15      


Asp Gly Leu Asp Lys Ala Ser Ile Ala Asn Ser Asp Gly Pro Thr Ala 
            20                  25                  30          


Gly Ser Gln Thr Pro Pro Phe Lys Arg Lys Gly Lys Leu Ser Thr Ile 
        35                  40                  45              


Gly Lys Ile Phe Lys Pro Trp Lys Trp Arg Lys Lys Lys Thr Ser Asp 
    50                  55                  60                  


Lys Phe Arg Glu Thr Ser Ala Val Leu Glu Arg Lys Ile Ser Thr Arg 
65                  70                  75                  80  


Gln Ser Arg Glu Glu Leu Ile Arg Arg Gly Val Leu Lys Glu Leu Pro 
                85                  90                  95      


Asp Gln Asp Gly Asp Val Thr Val Asn Phe Glu Asn Ser Asn Gly His 
            100                 105                 110         


Met Ile Pro Ile Gly Glu Glu Ser Thr Arg Glu Glu Asn Val Val Lys 
        115                 120                 125             


Ser Glu Glu Gly Asn Gly Ser Val Ser Glu Lys Thr Pro Pro Leu Glu 
    130                 135                 140                 


Glu Gln Ala Glu Asp Lys Lys Ala Gly Ser Ser His Ser Lys Lys Thr 
145                 150                 155                 160 


Thr Gly Ser Lys Ala Ser Ala Ser Pro Ser Thr Ser Ser Thr Ser Ser 
                165                 170                 175     


Arg Pro Lys Ala Ser Lys Glu Thr Val Ser Ser Lys Ala Gly Thr Val 
            180                 185                 190         


Gly Thr Thr Lys Gly Lys Arg Lys Thr Asp Lys Gln Pro Ile Thr Ser 
        195                 200                 205             


His Leu Ser Ser Asp Thr Thr Thr Ser Gly Thr Ser Asp Leu Lys Gly 
    210                 215                 220                 


Glu Pro Ala Glu Thr Arg Val Glu Ser Phe Lys Leu Glu Gln Thr Val 
225                 230                 235                 240 


Pro Gly Ala Glu Glu Gln Asn Thr Gly Lys Phe Lys Ser Met Val Pro 
                245                 250                 255     


Pro Pro Pro Val Ala Pro Ala Pro Ser Pro Leu Ala Pro Pro Leu Pro 
            260                 265                 270         


Leu Glu Asp Gln Cys Ile Thr Ala Ser Asp Thr Pro Val Val Leu Val 
        275                 280                 285             


Ser Val Gly Ala Asp Leu Pro Val Ser Ala Leu Asp Pro Ser Gln Leu 
    290                 295                 300                 


Leu Trp Ala Glu Glu Pro Thr Asn Arg Thr Thr Leu Tyr Ser Gly Thr 
305                 310                 315                 320 


Gly Leu Ser Val Asn Arg Glu Asn Ala Lys Cys Phe Thr Thr Lys Glu 
                325                 330                 335     


Glu Leu Gly Lys Thr Val Pro Gln Leu Leu Thr Pro Gly Leu Met Gly 
            340                 345                 350         


Glu Ser Ser Glu Ser Phe Ser Ala Ser Glu Asp Glu Gly His Arg Glu 
        355                 360                 365             


Tyr Gln Ala Asn Asp Ser Asp Ser Asp Gly Pro Ile Leu Tyr Thr Asp 
    370                 375                 380                 


Asp Glu Asp Glu Asp Glu Asp Glu Asp Gly Ser Gly Glu Ser Ala Leu 
385                 390                 395                 400 


Ala Ser Lys Ile Arg Arg Arg Asp Thr Leu Ala Ile Lys Leu Gly Asn 
                405                 410                 415     


Arg Pro Ser Lys Lys Glu Leu Glu Asp Lys Asn Ile Leu Gln Arg Thr 
            420                 425                 430         


Ser Glu Glu Glu Arg Gln Glu Ile Arg Gln Gln Ile Gly Thr Lys Leu 
        435                 440                 445             


Val Arg Arg Leu Ser Gln Arg Pro Thr Thr Glu Glu Leu Glu Gln Arg 
    450                 455                 460                 


Asn Ile Leu Lys Gln Lys Asn Glu Glu Glu Glu Gln Glu Ala Lys Met 
465                 470                 475                 480 


Glu Leu Lys Arg Arg Leu Ser Arg Lys Leu Ser Leu Arg Pro Thr Val 
                485                 490                 495     


Ala Glu Leu Gln Ala Arg Arg Ile Leu Arg Phe Asn Glu Tyr Val Glu 
            500                 505                 510         


Val Thr Asp Ser Pro Asp Tyr Asp Arg Arg Ala Asp Lys Pro Trp Ala 
        515                 520                 525             


Arg Leu Thr Pro Ala Asp Lys Ala Ala Ile Arg Lys Glu Leu Asn Glu 
    530                 535                 540                 


Phe Lys Ser Thr Glu Met Glu Val His Glu Glu Ser Arg Gln Phe Thr 
545                 550                 555                 560 


Arg Phe His Arg Pro 
                565 


<210>  4090
<211>  554
<212>  PRT
<213>  homo sapiens

<400>  4090

Met Asp Asn Ala Val Asp Gly Leu Asp Lys Ala Ser Ile Ala Asn Ser 
1               5                   10                  15      


Asp Gly Pro Thr Ala Gly Ser Gln Thr Pro Pro Phe Lys Arg Lys Gly 
            20                  25                  30          


Lys Leu Ser Thr Ile Gly Lys Ile Phe Lys Pro Trp Lys Trp Arg Lys 
        35                  40                  45              


Lys Lys Thr Ser Asp Lys Phe Arg Glu Thr Ser Ala Val Leu Glu Arg 
    50                  55                  60                  


Lys Ile Ser Thr Arg Gln Ser Arg Glu Glu Leu Ile Arg Arg Gly Val 
65                  70                  75                  80  


Leu Lys Glu Leu Pro Asp Gln Asp Gly Asp Val Thr Val Asn Phe Glu 
                85                  90                  95      


Asn Ser Asn Gly His Met Ile Pro Ile Gly Glu Glu Ser Thr Arg Glu 
            100                 105                 110         


Glu Asn Val Val Lys Ser Glu Glu Gly Asn Gly Ser Val Ser Glu Lys 
        115                 120                 125             


Thr Pro Pro Leu Glu Glu Gln Ala Glu Asp Lys Lys Ala Gly Ser Ser 
    130                 135                 140                 


His Ser Lys Lys Thr Thr Gly Ser Lys Ala Ser Ala Ser Pro Ser Thr 
145                 150                 155                 160 


Ser Ser Thr Ser Ser Arg Pro Lys Ala Ser Lys Glu Thr Val Ser Ser 
                165                 170                 175     


Lys Ala Gly Thr Val Gly Thr Thr Lys Gly Lys Arg Lys Thr Asp Lys 
            180                 185                 190         


Gln Pro Ile Thr Ser His Leu Ser Ser Asp Thr Thr Thr Ser Gly Thr 
        195                 200                 205             


Ser Asp Leu Lys Gly Glu Pro Ala Glu Thr Arg Val Glu Ser Phe Lys 
    210                 215                 220                 


Leu Glu Gln Thr Val Pro Gly Ala Glu Glu Gln Asn Thr Gly Lys Phe 
225                 230                 235                 240 


Lys Ser Met Val Pro Pro Pro Pro Val Ala Pro Ala Pro Ser Pro Leu 
                245                 250                 255     


Ala Pro Pro Leu Pro Leu Glu Asp Gln Cys Ile Thr Ala Ser Asp Thr 
            260                 265                 270         


Pro Val Val Leu Val Ser Val Gly Ala Asp Leu Pro Val Ser Ala Leu 
        275                 280                 285             


Asp Pro Ser Gln Leu Leu Trp Ala Glu Glu Pro Thr Asn Arg Thr Thr 
    290                 295                 300                 


Leu Tyr Ser Gly Thr Gly Leu Ser Val Asn Arg Glu Asn Ala Lys Cys 
305                 310                 315                 320 


Phe Thr Thr Lys Glu Glu Leu Gly Lys Thr Val Pro Gln Leu Leu Thr 
                325                 330                 335     


Pro Gly Leu Met Gly Glu Ser Ser Glu Ser Phe Ser Ala Ser Glu Asp 
            340                 345                 350         


Glu Gly His Arg Glu Tyr Gln Ala Asn Asp Ser Asp Ser Asp Gly Pro 
        355                 360                 365             


Ile Leu Tyr Thr Asp Asp Glu Asp Glu Asp Glu Asp Glu Asp Gly Ser 
    370                 375                 380                 


Gly Glu Ser Ala Leu Ala Ser Lys Ile Arg Arg Arg Asp Thr Leu Ala 
385                 390                 395                 400 


Ile Lys Leu Gly Asn Arg Pro Ser Lys Lys Glu Leu Glu Asp Lys Asn 
                405                 410                 415     


Ile Leu Gln Arg Thr Ser Glu Glu Glu Arg Gln Glu Ile Arg Gln Gln 
            420                 425                 430         


Ile Gly Thr Lys Leu Val Arg Arg Leu Ser Gln Arg Pro Thr Thr Glu 
        435                 440                 445             


Glu Leu Glu Gln Arg Asn Ile Leu Lys Gln Lys Asn Glu Glu Glu Glu 
    450                 455                 460                 


Gln Glu Ala Lys Met Glu Leu Lys Arg Arg Leu Ser Arg Lys Leu Ser 
465                 470                 475                 480 


Leu Arg Pro Thr Val Ala Glu Leu Gln Ala Arg Arg Ile Leu Arg Phe 
                485                 490                 495     


Asn Glu Tyr Val Glu Val Thr Asp Ser Pro Asp Tyr Asp Arg Arg Ala 
            500                 505                 510         


Asp Lys Pro Trp Ala Arg Leu Thr Pro Ala Asp Lys Ala Ala Ile Arg 
        515                 520                 525             


Lys Glu Leu Asn Glu Phe Lys Ser Thr Glu Met Glu Val His Glu Glu 
    530                 535                 540                 


Ser Arg Gln Phe Thr Arg Phe His Arg Pro 
545                 550                 


<210>  4091
<211>  314
<212>  PRT
<213>  homo sapiens

<400>  4091

Met Gln Asn Val Ile Asn Thr Val Lys Gly Lys Ala Leu Glu Val Ala 
1               5                   10                  15      


Glu Tyr Leu Thr Pro Val Leu Lys Glu Ser Lys Phe Lys Glu Thr Gly 
            20                  25                  30          


Val Ile Thr Pro Glu Glu Phe Val Ala Ala Gly Asp His Leu Val His 
        35                  40                  45              


His Cys Pro Thr Trp Gln Trp Ala Thr Gly Glu Glu Leu Lys Val Lys 
    50                  55                  60                  


Ala Tyr Leu Pro Thr Gly Lys Gln Phe Leu Val Thr Lys Asn Val Pro 
65                  70                  75                  80  


Cys Tyr Lys Arg Cys Lys Gln Met Glu Tyr Ser Asp Glu Leu Glu Ala 
                85                  90                  95      


Ile Ile Glu Glu Asp Asp Gly Asp Gly Gly Trp Val Asp Thr Tyr His 
            100                 105                 110         


Asn Thr Gly Ile Thr Gly Ile Thr Glu Ala Val Lys Glu Ile Thr Leu 
        115                 120                 125             


Glu Asn Lys Asp Asn Ile Arg Leu Gln Asp Cys Ser Ala Leu Cys Glu 
    130                 135                 140                 


Glu Glu Glu Asp Glu Asp Glu Gly Glu Ala Ala Asp Met Glu Glu Tyr 
145                 150                 155                 160 


Glu Glu Ser Gly Leu Leu Glu Thr Asp Glu Ala Thr Leu Asp Thr Arg 
                165                 170                 175     


Lys Ile Val Glu Ala Cys Lys Ala Lys Thr Asp Ala Gly Gly Glu Asp 
            180                 185                 190         


Ala Ile Leu Gln Thr Arg Thr Tyr Asp Leu Tyr Ile Thr Tyr Asp Lys 
        195                 200                 205             


Tyr Tyr Gln Thr Pro Arg Leu Trp Leu Phe Gly Tyr Asp Glu Gln Arg 
    210                 215                 220                 


Gln Pro Leu Thr Val Glu His Met Tyr Glu Asp Ile Ser Gln Asp His 
225                 230                 235                 240 


Val Lys Lys Thr Val Thr Ile Glu Asn His Pro His Leu Pro Pro Pro 
                245                 250                 255     


Pro Met Cys Ser Val His Pro Cys Arg His Ala Glu Val Met Lys Lys 
            260                 265                 270         


Ile Ile Glu Thr Val Ala Glu Gly Gly Gly Glu Leu Gly Val His Met 
        275                 280                 285             


Tyr Leu Leu Ile Phe Leu Lys Phe Val Gln Ala Val Ile Pro Thr Ile 
    290                 295                 300                 


Glu Tyr Asp Tyr Thr Arg His Phe Thr Met 
305                 310                 


<210>  4092
<211>  256
<212>  PRT
<213>  homo sapiens

<400>  4092

Met His Pro Glu Gly Gly Gln Phe Val Pro Gln Leu Leu Gly His Leu 
1               5                   10                  15      


Leu Ala Thr Lys Leu Lys Arg Phe Leu Leu Ser Lys Gly Gly Arg Arg 
            20                  25                  30          


Ala Gln Ile Pro Asp Val Ser Arg Ala Thr Pro His Thr Ile Asp Glu 
        35                  40                  45              


Met Pro Glu Ala Ala Val Lys Ser Thr Ala Asn Lys Tyr Gln Val Phe 
    50                  55                  60                  


Phe Phe Gly Thr His Glu Thr Ala Phe Leu Gly Pro Lys Asp Leu Phe 
65                  70                  75                  80  


Pro Tyr Glu Glu Ser Lys Glu Lys Phe Gly Lys Pro Asn Lys Arg Lys 
                85                  90                  95      


Gly Phe Ser Glu Gly Leu Trp Glu Ile Glu Asn Asn Pro Thr Val Lys 
            100                 105                 110         


Ala Ser Gly Tyr Gln Ser Ser Gln Lys Lys Ser Cys Val Glu Glu Pro 
        115                 120                 125             


Glu Pro Glu Pro Glu Ala Ala Glu Gly Asp Gly Asp Lys Lys Gly Asn 
    130                 135                 140                 


Ala Glu Gly Ser Ser Asp Glu Glu Gly Lys Leu Val Ile Asp Glu Pro 
145                 150                 155                 160 


Ala Lys Glu Lys Asn Glu Lys Gly Ala Leu Lys Arg Arg Ala Gly Asp 
                165                 170                 175     


Leu Leu Glu Asp Ser Pro Lys Arg Pro Lys Glu Ala Glu Asn Pro Glu 
            180                 185                 190         


Gly Glu Glu Lys Glu Ala Ala Thr Leu Glu Val Glu Arg Pro Leu Pro 
        195                 200                 205             


Met Glu Val Glu Lys Asn Ser Thr Pro Ser Glu Pro Gly Ser Gly Arg 
    210                 215                 220                 


Gly Pro Pro Gln Glu Glu Glu Glu Glu Glu Asp Glu Glu Glu Glu Ala 
225                 230                 235                 240 


Thr Lys Glu Asp Ala Glu Ala Pro Gly Ile Arg Asp His Glu Ser Leu 
                245                 250                 255     


<210>  4093
<211>  233
<212>  PRT
<213>  homo sapiens

<400>  4093

Met Glu Gln Arg Ala Gly Gly Asn Arg Val Gln Thr Ser Thr Leu Asn 
1               5                   10                  15      


Cys Ala Gly Ala Ala Val Ile Asp Glu Met Pro Glu Ala Ala Val Lys 
            20                  25                  30          


Ser Thr Ala Asn Lys Tyr Gln Val Phe Phe Phe Gly Thr His Glu Thr 
        35                  40                  45              


Ala Phe Leu Gly Pro Lys Asp Leu Phe Pro Tyr Glu Glu Ser Lys Glu 
    50                  55                  60                  


Lys Phe Gly Lys Pro Asn Lys Arg Lys Gly Phe Ser Glu Gly Leu Trp 
65                  70                  75                  80  


Glu Ile Glu Asn Asn Pro Thr Val Lys Ala Ser Gly Tyr Gln Ser Ser 
                85                  90                  95      


Gln Lys Lys Ser Cys Val Glu Glu Pro Glu Pro Glu Pro Glu Ala Ala 
            100                 105                 110         


Glu Gly Asp Gly Asp Lys Lys Gly Asn Ala Glu Gly Ser Ser Asp Glu 
        115                 120                 125             


Glu Gly Lys Leu Val Ile Asp Glu Pro Ala Lys Glu Lys Asn Glu Lys 
    130                 135                 140                 


Gly Ala Leu Lys Arg Arg Ala Gly Asp Leu Leu Glu Asp Ser Pro Lys 
145                 150                 155                 160 


Arg Pro Lys Glu Ala Glu Asn Pro Glu Gly Glu Glu Lys Glu Ala Ala 
                165                 170                 175     


Thr Leu Glu Val Glu Arg Pro Leu Pro Met Glu Val Glu Lys Asn Ser 
            180                 185                 190         


Thr Pro Ser Glu Pro Gly Ser Gly Arg Gly Pro Pro Gln Glu Glu Glu 
        195                 200                 205             


Glu Glu Glu Asp Glu Glu Glu Glu Ala Thr Lys Glu Asp Ala Glu Ala 
    210                 215                 220                 


Pro Gly Ile Arg Asp His Glu Ser Leu 
225                 230             


<210>  4094
<211>  1150
<212>  PRT
<213>  homo sapiens

<400>  4094

Met Ala Gln Phe Gly Gly Gln Lys Asn Pro Pro Trp Ala Thr Gln Phe 
1               5                   10                  15      


Thr Ala Thr Ala Val Ser Gln Pro Ala Ala Leu Gly Val Gln Gln Pro 
            20                  25                  30          


Ser Leu Leu Gly Ala Ser Pro Thr Ile Tyr Thr Gln Gln Thr Ala Leu 
        35                  40                  45              


Ala Ala Ala Gly Leu Thr Thr Gln Thr Pro Ala Asn Tyr Gln Leu Thr 
    50                  55                  60                  


Gln Thr Ala Ala Leu Gln Gln Gln Ala Ala Ala Ala Ala Ala Ala Leu 
65                  70                  75                  80  


Gln Gln Gln Tyr Ser Gln Pro Gln Gln Ala Leu Tyr Ser Val Gln Gln 
                85                  90                  95      


Gln Leu Gln Gln Pro Gln Gln Thr Leu Leu Thr Gln Pro Ala Val Ala 
            100                 105                 110         


Leu Pro Thr Ser Leu Ser Leu Ser Thr Pro Gln Pro Thr Ala Gln Ile 
        115                 120                 125             


Thr Val Ser Tyr Pro Thr Pro Arg Ser Ser Gln Gln Gln Thr Gln Pro 
    130                 135                 140                 


Gln Lys Gln Arg Val Phe Thr Gly Val Val Thr Lys Leu His Asp Thr 
145                 150                 155                 160 


Phe Gly Phe Val Asp Glu Asp Val Phe Phe Gln Leu Ser Ala Val Lys 
                165                 170                 175     


Gly Lys Thr Pro Gln Val Gly Asp Arg Val Leu Val Glu Ala Thr Tyr 
            180                 185                 190         


Asn Pro Asn Met Pro Phe Lys Trp Asn Ala Gln Arg Ile Gln Thr Leu 
        195                 200                 205             


Pro Asn Gln Asn Gln Ser Gln Thr Gln Pro Leu Leu Lys Thr Pro Pro 
    210                 215                 220                 


Ala Val Leu Gln Pro Ile Ala Pro Gln Thr Thr Phe Gly Val Gln Thr 
225                 230                 235                 240 


Gln Pro Gln Pro Gln Ser Leu Leu Gln Ala Gln Ile Ser Ala Ala Ser 
                245                 250                 255     


Ile Thr Pro Leu Leu Gln Thr Gln Pro Gln Pro Leu Leu Gln Gln Pro 
            260                 265                 270         


Gln Gln Lys Ala Gly Leu Leu Gln Pro Pro Val Arg Ile Val Ser Gln 
        275                 280                 285             


Pro Gln Pro Ala Arg Arg Leu Asp Pro Pro Ser Arg Phe Ser Gly Arg 
    290                 295                 300                 


Asn Asp Arg Gly Asp Gln Val Pro Asn Arg Lys Asp Asp Arg Ser Arg 
305                 310                 315                 320 


Glu Arg Glu Arg Glu Arg Arg Arg Ser Arg Glu Arg Ser Pro Gln Arg 
                325                 330                 335     


Lys Arg Ser Arg Glu Arg Ser Pro Arg Arg Glu Arg Glu Arg Ser Pro 
            340                 345                 350         


Arg Arg Val Arg Arg Val Val Pro Arg Tyr Thr Val Gln Phe Ser Lys 
        355                 360                 365             


Phe Ser Leu Asp Cys Pro Ser Cys Asp Met Met Glu Leu Arg Arg Arg 
    370                 375                 380                 


Tyr Gln Asn Leu Tyr Ile Pro Ser Asp Phe Phe Asp Ala Gln Phe Thr 
385                 390                 395                 400 


Trp Val Asp Ala Phe Pro Leu Ser Arg Pro Phe Gln Leu Gly Asn Tyr 
                405                 410                 415     


Cys Asn Phe Tyr Val Met His Arg Glu Val Glu Ser Leu Glu Lys Asn 
            420                 425                 430         


Met Ala Ile Leu Asp Pro Pro Asp Ala Asp His Leu Tyr Ser Ala Lys 
        435                 440                 445             


Val Met Leu Met Ala Ser Pro Ser Met Glu Asp Leu Tyr His Lys Ser 
    450                 455                 460                 


Cys Ala Leu Ala Glu Asp Pro Gln Glu Leu Arg Asp Gly Phe Gln His 
465                 470                 475                 480 


Pro Ala Arg Leu Val Lys Phe Leu Val Gly Met Lys Gly Lys Asp Glu 
                485                 490                 495     


Ala Met Ala Ile Gly Gly His Trp Ser Pro Ser Leu Asp Gly Pro Asp 
            500                 505                 510         


Pro Glu Lys Asp Pro Ser Val Leu Ile Lys Thr Ala Ile Arg Cys Cys 
        515                 520                 525             


Lys Ala Leu Thr Gly Ile Asp Leu Ser Val Cys Thr Gln Trp Tyr Arg 
    530                 535                 540                 


Phe Ala Glu Ile Arg Tyr His Arg Pro Glu Glu Thr His Lys Gly Arg 
545                 550                 555                 560 


Thr Val Pro Ala His Val Glu Thr Val Val Leu Phe Phe Pro Asp Val 
                565                 570                 575     


Trp His Cys Leu Pro Thr Arg Ser Glu Trp Glu Thr Leu Ser Arg Gly 
            580                 585                 590         


Tyr Lys Gln Gln Leu Val Glu Lys Leu Gln Gly Glu Arg Lys Glu Ala 
        595                 600                 605             


Asp Gly Glu Gln Asp Glu Glu Glu Lys Asp Asp Gly Glu Ala Lys Glu 
    610                 615                 620                 


Ile Ser Thr Pro Thr His Trp Ser Lys Leu Asp Pro Lys Thr Met Lys 
625                 630                 635                 640 


Val Asn Asp Leu Arg Lys Glu Leu Glu Ser Arg Ala Leu Ser Ser Lys 
                645                 650                 655     


Gly Leu Lys Ser Gln Leu Ile Ala Arg Leu Thr Lys Gln Leu Lys Val 
            660                 665                 670         


Glu Glu Gln Lys Glu Glu Gln Lys Glu Leu Glu Lys Ser Glu Lys Glu 
        675                 680                 685             


Glu Asp Glu Asp Asp Asp Arg Lys Ser Glu Asp Asp Lys Glu Glu Glu 
    690                 695                 700                 


Glu Arg Lys Arg Gln Glu Glu Ile Glu Arg Gln Arg Arg Glu Arg Arg 
705                 710                 715                 720 


Tyr Ile Leu Pro Asp Glu Pro Ala Ile Ile Val His Pro Asn Trp Ala 
                725                 730                 735     


Ala Lys Ser Gly Lys Phe Asp Cys Ser Ile Met Ser Leu Ser Val Leu 
            740                 745                 750         


Leu Asp Tyr Arg Leu Glu Asp Asn Lys Glu His Ser Phe Glu Val Ser 
        755                 760                 765             


Leu Phe Ala Glu Leu Phe Asn Glu Met Leu Gln Arg Asp Phe Gly Val 
    770                 775                 780                 


Arg Ile Tyr Lys Ser Leu Leu Ser Leu Pro Glu Lys Glu Asp Lys Lys 
785                 790                 795                 800 


Glu Lys Asp Lys Lys Ser Lys Lys Asp Glu Arg Lys Asp Lys Lys Glu 
                805                 810                 815     


Glu Arg Asp Asp Glu Thr Asp Glu Pro Lys Pro Lys Arg Arg Lys Ser 
            820                 825                 830         


Gly Asp Asp Lys Asp Lys Lys Glu Asp Arg Asp Glu Arg Lys Lys Glu 
        835                 840                 845             


Asp Lys Arg Lys Asp Asp Ser Lys Asp Asp Asp Glu Thr Glu Glu Asp 
    850                 855                 860                 


Asn Asn Gln Asp Glu Tyr Asp Pro Met Glu Ala Glu Glu Ala Glu Asp 
865                 870                 875                 880 


Glu Glu Asp Asp Arg Asp Glu Glu Glu Met Thr Lys Arg Asp Asp Lys 
                885                 890                 895     


Arg Asp Ile Asn Arg Tyr Cys Lys Glu Arg Pro Ser Lys Asp Lys Glu 
            900                 905                 910         


Lys Glu Lys Thr Gln Met Ile Thr Ile Asn Arg Asp Leu Leu Met Ala 
        915                 920                 925             


Phe Val Tyr Phe Asp Gln Ser His Cys Gly Tyr Leu Leu Glu Lys Asp 
    930                 935                 940                 


Leu Glu Glu Ile Leu Tyr Thr Leu Gly Leu His Leu Ser Arg Ala Gln 
945                 950                 955                 960 


Val Lys Lys Leu Leu Asn Lys Val Val Leu Arg Glu Ser Cys Phe Tyr 
                965                 970                 975     


Arg Lys Leu Thr Asp Thr Ser Lys Asp Glu Glu Asn His Glu Glu Ser 
            980                 985                 990         


Glu Ser Leu Gln Glu Asp Met Leu  Gly Asn Arg Leu Leu  Leu Pro Thr 
        995                 1000                 1005             


Pro Thr  Val Lys Gln Glu Ser  Lys Asp Val Glu Glu  Asn Val Gly 
    1010                 1015                 1020             


Leu Ile  Val Tyr Asn Gly Ala  Met Val Asp Val Gly  Ser Leu Leu 
    1025                 1030                 1035             


Gln Lys  Leu Glu Lys Ser Glu  Lys Val Arg Ala Glu  Val Glu Gln 
    1040                 1045                 1050             


Lys Leu  Gln Leu Leu Glu Glu  Lys Thr Asp Glu Asp  Glu Lys Thr 
    1055                 1060                 1065             


Ile Leu  Asn Leu Glu Asn Ser  Asn Lys Ser Leu Ser  Gly Glu Leu 
    1070                 1075                 1080             


Arg Glu  Val Lys Lys Asp Leu  Ser Gln Leu Gln Glu  Asn Leu Lys 
    1085                 1090                 1095             


Ile Ser  Glu Asn Met Asn Leu  Gln Phe Glu Asn Gln  Met Asn Lys 
    1100                 1105                 1110             


Thr Ile  Arg Asn Leu Ser Thr  Val Met Asp Glu Ile  His Thr Val 
    1115                 1120                 1125             


Leu Lys  Lys Asp Asn Val Lys  Asn Glu Asp Lys Asp  Gln Lys Ser 
    1130                 1135                 1140             


Lys Glu  Asn Gly Ala Ser Val  
    1145                 1150 


<210>  4095
<211>  517
<212>  PRT
<213>  homo sapiens

<400>  4095

Met Pro Pro Pro Gly Lys Val Pro Arg Lys Glu Asn Leu Trp Leu Gln 
1               5                   10                  15      


Cys Glu Trp Gly Ser Cys Ser Phe Val Cys Ser Thr Met Glu Lys Phe 
            20                  25                  30          


Phe Glu His Val Thr Gln His Leu Gln Gln His Leu His Gly Ser Gly 
        35                  40                  45              


Glu Glu Glu Glu Glu Glu Glu Glu Asp Asp Pro Leu Glu Glu Glu Phe 
    50                  55                  60                  


Ser Cys Leu Trp Gln Glu Cys Gly Phe Cys Ser Leu Asp Ser Ser Ala 
65                  70                  75                  80  


Asp Leu Ile Arg His Val Tyr Phe His Cys Tyr His Thr Lys Leu Lys 
                85                  90                  95      


Gln Trp Gly Leu Gln Ala Leu Gln Ser Gln Ala Asp Leu Gly Pro Cys 
            100                 105                 110         


Ile Leu Asp Phe Gln Ser Arg Asn Val Ile Pro Asp Ile Pro Asp His 
        115                 120                 125             


Phe Leu Cys Leu Trp Glu His Cys Glu Asn Ser Phe Asp Asn Pro Glu 
    130                 135                 140                 


Trp Phe Tyr Arg His Val Glu Ala His Ser Leu Cys Cys Glu Tyr Glu 
145                 150                 155                 160 


Ala Val Gly Lys Asp Asn Pro Val Val Leu Cys Gly Trp Lys Gly Cys 
                165                 170                 175     


Thr Cys Thr Phe Lys Asp Arg Ser Lys Leu Arg Glu His Leu Arg Ser 
            180                 185                 190         


His Thr Gln Glu Lys Val Val Ala Cys Pro Thr Cys Gly Gly Met Phe 
        195                 200                 205             


Ala Asn Asn Thr Lys Phe Leu Asp His Ile Arg Arg Gln Thr Ser Leu 
    210                 215                 220                 


Asp Gln Gln His Phe Gln Cys Ser His Cys Ser Lys Arg Phe Ala Thr 
225                 230                 235                 240 


Glu Arg Leu Leu Arg Asp His Met Arg Asn His Val Asn His Tyr Lys 
                245                 250                 255     


Cys Pro Leu Cys Asp Met Thr Cys Pro Leu Pro Ser Ser Leu Arg Asn 
            260                 265                 270         


His Met Arg Phe Arg His Ser Glu Asp Arg Pro Phe Lys Cys Asp Cys 
        275                 280                 285             


Cys Asp Tyr Ser Cys Lys Asn Leu Ile Asp Leu Gln Lys His Leu Asp 
    290                 295                 300                 


Thr His Ser Glu Glu Pro Ala Tyr Arg Cys Asp Phe Glu Asn Cys Thr 
305                 310                 315                 320 


Phe Ser Ala Arg Ser Leu Cys Ser Ile Lys Ser His Tyr Arg Lys Val 
                325                 330                 335     


His Glu Gly Asp Ser Glu Pro Arg Tyr Lys Cys His Val Cys Asp Lys 
            340                 345                 350         


Cys Phe Thr Arg Gly Asn Asn Leu Thr Val His Leu Arg Lys Lys His 
        355                 360                 365             


Gln Phe Lys Trp Pro Ser Gly His Pro Arg Phe Arg Tyr Lys Glu His 
    370                 375                 380                 


Glu Asp Gly Tyr Met Arg Leu Gln Leu Val Arg Tyr Glu Ser Val Glu 
385                 390                 395                 400 


Leu Thr Gln Gln Leu Leu Arg Gln Pro Gln Glu Gly Ser Gly Leu Gly 
                405                 410                 415     


Thr Ser Leu Asn Glu Ser Ser Leu Gln Gly Ile Ile Leu Glu Thr Val 
            420                 425                 430         


Pro Gly Glu Pro Gly Arg Lys Glu Glu Glu Glu Glu Gly Lys Gly Ser 
        435                 440                 445             


Glu Gly Thr Ala Leu Ser Ala Ser Gln Asp Asn Pro Ser Ser Val Ile 
    450                 455                 460                 


His Val Val Asn Gln Thr Asn Ala Gln Gly Gln Gln Glu Ile Val Tyr 
465                 470                 475                 480 


Tyr Val Leu Ser Glu Ala Pro Gly Glu Pro Pro Pro Ala Pro Glu Pro 
                485                 490                 495     


Pro Ser Gly Gly Ile Met Glu Lys Leu Gln Gly Ile Ala Glu Glu Pro 
            500                 505                 510         


Glu Ile Gln Met Val 
        515         


<210>  4096
<211>  161
<212>  PRT
<213>  homo sapiens

<400>  4096

Met Lys Ala Val Ser Pro Val Arg Pro Ser Gly Arg Lys Ala Pro Ser 
1               5                   10                  15      


Gly Cys Gly Gly Gly Glu Leu Ala Leu Arg Cys Leu Ala Glu His Gly 
            20                  25                  30          


His Ser Leu Gly Gly Ser Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala 
        35                  40                  45              


Arg Cys Lys Ala Ala Glu Ala Ala Ala Asp Glu Pro Ala Leu Cys Leu 
    50                  55                  60                  


Gln Cys Asp Met Asn Asp Cys Tyr Ser Arg Leu Arg Arg Leu Val Pro 
65                  70                  75                  80  


Thr Ile Pro Pro Asn Lys Lys Val Ser Lys Val Glu Ile Leu Gln His 
                85                  90                  95      


Val Ile Asp Tyr Ile Leu Asp Leu Gln Leu Ala Leu Glu Thr His Pro 
            100                 105                 110         


Ala Leu Leu Arg Gln Pro Pro Pro Pro Ala Pro Pro His His Pro Ala 
        115                 120                 125             


Gly Thr Cys Pro Ala Ala Pro Pro Arg Thr Pro Leu Thr Ala Leu Asn 
    130                 135                 140                 


Thr Asp Pro Ala Gly Ala Val Asn Lys Gln Gly Asp Ser Ile Leu Cys 
145                 150                 155                 160 


Arg 
    


<210>  4097
<211>  1216
<212>  PRT
<213>  homo sapiens

<400>  4097

Met Ala Gly Ala Gln Pro Gly Val His Ala Leu Gln Leu Lys Pro Val 
1               5                   10                  15      


Cys Val Ser Asp Ser Leu Lys Lys Gly Thr Lys Phe Val Lys Trp Asp 
            20                  25                  30          


Asp Asp Ser Thr Ile Val Thr Pro Ile Ile Leu Arg Thr Asp Pro Gln 
        35                  40                  45              


Gly Phe Phe Phe Tyr Trp Thr Asp Gln Asn Lys Glu Thr Glu Leu Leu 
    50                  55                  60                  


Asp Leu Ser Leu Val Lys Asp Ala Arg Cys Gly Arg His Ala Lys Ala 
65                  70                  75                  80  


Pro Lys Asp Pro Lys Leu Arg Glu Leu Leu Asp Val Gly Asn Ile Gly 
                85                  90                  95      


Arg Leu Glu Gln Arg Met Ile Thr Val Val Tyr Gly Pro Asp Leu Val 
            100                 105                 110         


Asn Ile Ser His Leu Asn Leu Val Ala Phe Gln Glu Glu Val Ala Lys 
        115                 120                 125             


Glu Trp Thr Asn Glu Val Phe Ser Leu Ala Thr Asn Leu Leu Ala Gln 
    130                 135                 140                 


Asn Met Ser Arg Asp Ala Phe Leu Glu Lys Ala Tyr Thr Lys Leu Lys 
145                 150                 155                 160 


Leu Gln Val Thr Pro Glu Gly Arg Ile Pro Leu Lys Asn Ile Tyr Arg 
                165                 170                 175     


Leu Phe Ser Ala Asp Arg Lys Arg Val Glu Thr Ala Leu Glu Ala Cys 
            180                 185                 190         


Ser Leu Pro Ser Ser Arg Asn Asp Ser Ile Pro Gln Glu Asp Phe Thr 
        195                 200                 205             


Pro Glu Val Tyr Arg Val Phe Leu Asn Asn Leu Cys Pro Arg Pro Glu 
    210                 215                 220                 


Ile Asp Asn Ile Phe Ser Glu Phe Gly Ala Lys Ser Lys Pro Tyr Leu 
225                 230                 235                 240 


Thr Val Asp Gln Met Met Asp Phe Ile Asn Leu Lys Gln Arg Asp Pro 
                245                 250                 255     


Arg Leu Asn Glu Ile Leu Tyr Pro Pro Leu Lys Gln Glu Gln Val Gln 
            260                 265                 270         


Val Leu Ile Glu Lys Tyr Glu Pro Asn Asn Ser Leu Ala Arg Lys Gly 
        275                 280                 285             


Gln Ile Ser Val Asp Gly Phe Met Arg Tyr Leu Ser Gly Glu Glu Asn 
    290                 295                 300                 


Gly Val Val Ser Pro Glu Lys Leu Asp Leu Asn Glu Asp Met Ser Gln 
305                 310                 315                 320 


Pro Leu Ser His Tyr Phe Ile Asn Ser Ser His Asn Thr Tyr Leu Thr 
                325                 330                 335     


Ala Gly Gln Leu Ala Gly Asn Ser Ser Val Glu Met Tyr Arg Gln Val 
            340                 345                 350         


Leu Leu Ser Gly Cys Arg Cys Val Glu Leu Asp Cys Trp Lys Gly Arg 
        355                 360                 365             


Thr Ala Glu Glu Glu Pro Val Ile Thr His Gly Phe Thr Met Thr Thr 
    370                 375                 380                 


Glu Ile Ser Phe Lys Glu Val Ile Glu Ala Ile Ala Glu Cys Ala Phe 
385                 390                 395                 400 


Lys Thr Ser Pro Phe Pro Ile Leu Leu Ser Phe Glu Asn His Val Asp 
                405                 410                 415     


Ser Pro Lys Gln Gln Ala Lys Met Ala Glu Tyr Cys Arg Leu Ile Phe 
            420                 425                 430         


Gly Asp Ala Leu Leu Met Glu Pro Leu Glu Lys Tyr Pro Leu Glu Ser 
        435                 440                 445             


Gly Val Pro Leu Pro Ser Pro Met Asp Leu Met Tyr Lys Ile Leu Val 
    450                 455                 460                 


Lys Asn Lys Lys Lys Ser His Lys Ser Ser Glu Gly Ser Gly Lys Lys 
465                 470                 475                 480 


Lys Leu Ser Glu Gln Ala Ser Asn Thr Tyr Ser Asp Ser Ser Ser Met 
                485                 490                 495     


Phe Glu Pro Ser Ser Pro Gly Ala Gly Glu Ala Asp Thr Glu Ser Asp 
            500                 505                 510         


Asp Asp Asp Asp Asp Asp Asp Cys Lys Lys Ser Ser Met Asp Glu Gly 
        515                 520                 525             


Thr Ala Gly Ser Glu Ala Met Ala Thr Glu Glu Met Ser Asn Leu Val 
    530                 535                 540                 


Asn Tyr Ile Gln Pro Val Lys Phe Glu Ser Phe Glu Ile Ser Lys Lys 
545                 550                 555                 560 


Arg Asn Lys Ser Phe Glu Met Ser Ser Phe Val Glu Thr Lys Gly Leu 
                565                 570                 575     


Glu Gln Leu Thr Lys Ser Pro Val Glu Phe Val Glu Tyr Asn Lys Met 
            580                 585                 590         


Gln Leu Ser Arg Ile Tyr Pro Lys Gly Thr Arg Val Asp Ser Ser Asn 
        595                 600                 605             


Tyr Met Pro Gln Leu Phe Trp Asn Ala Gly Cys Gln Met Val Ala Leu 
    610                 615                 620                 


Asn Phe Gln Thr Met Asp Leu Ala Met Gln Ile Asn Met Gly Met Tyr 
625                 630                 635                 640 


Glu Tyr Asn Gly Lys Ser Gly Tyr Arg Leu Lys Pro Glu Phe Met Arg 
                645                 650                 655     


Arg Pro Asp Lys His Phe Asp Pro Phe Thr Glu Gly Ile Val Asp Gly 
            660                 665                 670         


Ile Val Ala Asn Thr Leu Ser Val Lys Ile Ile Ser Gly Gln Phe Leu 
        675                 680                 685             


Ser Asp Lys Lys Val Gly Thr Tyr Val Glu Val Asp Met Phe Gly Leu 
    690                 695                 700                 


Pro Val Asp Thr Arg Arg Lys Ala Phe Lys Thr Lys Thr Ser Gln Gly 
705                 710                 715                 720 


Asn Ala Val Asn Pro Val Trp Glu Glu Glu Pro Ile Val Phe Lys Lys 
                725                 730                 735     


Val Val Leu Pro Thr Leu Ala Cys Leu Arg Ile Ala Val Tyr Glu Glu 
            740                 745                 750         


Gly Gly Lys Phe Ile Gly His Arg Ile Leu Pro Val Gln Ala Ile Arg 
        755                 760                 765             


Pro Gly Tyr His Tyr Ile Cys Leu Arg Asn Glu Arg Asn Gln Pro Leu 
    770                 775                 780                 


Thr Leu Pro Ala Val Phe Val Tyr Ile Glu Val Lys Asp Tyr Val Pro 
785                 790                 795                 800 


Asp Thr Tyr Ala Asp Val Ile Glu Ala Leu Ser Asn Pro Ile Arg Tyr 
                805                 810                 815     


Val Asn Leu Met Glu Gln Arg Ala Lys Gln Leu Ala Ala Leu Thr Leu 
            820                 825                 830         


Glu Asp Glu Glu Glu Val Lys Lys Glu Ala Asp Pro Gly Glu Thr Pro 
        835                 840                 845             


Ser Glu Ala Pro Ser Glu Ala Arg Thr Thr Pro Ala Glu Asn Gly Val 
    850                 855                 860                 


Asn His Thr Thr Thr Leu Thr Pro Lys Pro Pro Ser Gln Ala Leu His 
865                 870                 875                 880 


Ser Gln Pro Ala Pro Gly Ser Val Lys Ala Pro Ala Lys Thr Glu Asp 
                885                 890                 895     


Leu Ile Gln Ser Val Leu Thr Glu Val Glu Ala Gln Thr Ile Glu Glu 
            900                 905                 910         


Leu Lys Gln Gln Lys Ser Phe Val Lys Leu Gln Lys Lys His Tyr Lys 
        915                 920                 925             


Glu Met Lys Asp Leu Val Lys Arg His His Lys Lys Thr Thr Asp Leu 
    930                 935                 940                 


Ile Lys Glu His Thr Thr Lys Tyr Asn Glu Ile Gln Asn Asp Tyr Leu 
945                 950                 955                 960 


Arg Arg Arg Ala Ala Leu Glu Lys Ser Ala Lys Lys Asp Ser Lys Lys 
                965                 970                 975     


Lys Ser Glu Pro Ser Ser Pro Asp His Gly Ser Ser Thr Ile Glu Gln 
            980                 985                 990         


Asp Leu Ala Ala Leu Asp Ala Glu  Met Thr Gln Lys Leu  Ile Asp Leu 
        995                 1000                 1005             


Lys Asp  Lys Gln Gln Gln Gln  Leu Leu Asn Leu Arg  Gln Glu Gln 
    1010                 1015                 1020             


Tyr Tyr  Ser Glu Lys Tyr Gln  Lys Arg Glu His Ile  Lys Leu Leu 
    1025                 1030                 1035             


Ile Gln  Lys Leu Thr Asp Val  Ala Glu Glu Cys Gln  Asn Asn Gln 
    1040                 1045                 1050             


Leu Lys  Lys Leu Lys Glu Ile  Cys Glu Lys Glu Lys  Lys Glu Leu 
    1055                 1060                 1065             


Lys Lys  Lys Met Asp Lys Lys  Arg Gln Glu Lys Ile  Thr Glu Ala 
    1070                 1075                 1080             


Lys Ser  Lys Asp Lys Ser Gln  Met Glu Glu Glu Lys  Thr Glu Met 
    1085                 1090                 1095             


Ile Arg  Ser Tyr Ile Gln Glu  Val Val Gln Tyr Ile  Lys Arg Leu 
    1100                 1105                 1110             


Glu Glu  Ala Gln Ser Lys Arg  Gln Glu Lys Leu Val  Glu Lys His 
    1115                 1120                 1125             


Lys Glu  Ile Arg Gln Gln Ile  Leu Asp Glu Lys Pro  Lys Leu Gln 
    1130                 1135                 1140             


Val Glu  Leu Glu Gln Glu Tyr  Gln Asp Lys Phe Lys  Arg Leu Pro 
    1145                 1150                 1155             


Leu Glu  Ile Leu Glu Phe Val  Gln Glu Ala Met Lys  Gly Lys Ile 
    1160                 1165                 1170             


Ser Glu  Asp Ser Asn His Gly  Ser Ala Pro Leu Ser  Leu Ser Ser 
    1175                 1180                 1185             


Asp Pro  Gly Lys Val Asn His  Lys Thr Pro Ser Ser  Glu Glu Leu 
    1190                 1195                 1200             


Gly Gly  Asp Ile Pro Gly Lys  Glu Phe Asp Thr Pro  Leu 
    1205                 1210                 1215     


<210>  4098
<211>  1173
<212>  PRT
<213>  homo sapiens

<400>  4098

Met Ala Gly Ala Gln Pro Gly Val His Ala Leu Gln Leu Lys Pro Val 
1               5                   10                  15      


Cys Val Ser Asp Ser Leu Lys Lys Gly Thr Lys Phe Val Lys Trp Asp 
            20                  25                  30          


Asp Asp Ser Thr Ile Val Thr Pro Ile Ile Leu Arg Thr Asp Pro Gln 
        35                  40                  45              


Gly Phe Phe Phe Tyr Trp Thr Asp Gln Asn Lys Glu Thr Glu Leu Leu 
    50                  55                  60                  


Asp Leu Ser Leu Val Lys Asp Ala Arg Cys Gly Arg His Ala Lys Ala 
65                  70                  75                  80  


Pro Lys Asp Pro Lys Leu Arg Glu Leu Leu Asp Val Gly Asn Ile Gly 
                85                  90                  95      


Arg Leu Glu Gln Arg Met Ile Thr Val Val Tyr Gly Pro Asp Leu Val 
            100                 105                 110         


Asn Ile Ser His Leu Asn Leu Val Ala Phe Gln Glu Glu Val Ala Lys 
        115                 120                 125             


Glu Trp Thr Asn Glu Val Phe Ser Leu Ala Thr Asn Leu Leu Ala Gln 
    130                 135                 140                 


Asn Met Ser Arg Asp Ala Phe Leu Glu Lys Ala Tyr Thr Lys Leu Lys 
145                 150                 155                 160 


Leu Gln Val Thr Pro Glu Gly Arg Ile Pro Leu Lys Asn Ile Tyr Arg 
                165                 170                 175     


Leu Phe Ser Ala Asp Arg Lys Arg Val Glu Thr Ala Leu Glu Ala Cys 
            180                 185                 190         


Ser Leu Pro Ser Ser Arg Asn Asp Ser Ile Pro Gln Glu Asp Phe Thr 
        195                 200                 205             


Pro Glu Val Tyr Arg Val Phe Leu Asn Asn Leu Cys Pro Arg Pro Glu 
    210                 215                 220                 


Ile Asp Asn Ile Phe Ser Glu Phe Gly Ala Lys Ser Lys Pro Tyr Leu 
225                 230                 235                 240 


Thr Val Asp Gln Met Met Asp Phe Ile Asn Leu Lys Gln Arg Asp Pro 
                245                 250                 255     


Arg Leu Asn Glu Ile Leu Tyr Pro Pro Leu Lys Gln Glu Gln Val Gln 
            260                 265                 270         


Val Leu Ile Glu Lys Tyr Glu Pro Asn Asn Ser Leu Ala Arg Lys Gly 
        275                 280                 285             


Gln Ile Ser Val Asp Gly Phe Met Arg Tyr Leu Ser Gly Glu Glu Asn 
    290                 295                 300                 


Gly Val Val Ser Pro Glu Lys Leu Asp Leu Asn Glu Asp Met Ser Gln 
305                 310                 315                 320 


Pro Leu Ser His Tyr Phe Ile Asn Ser Ser His Asn Thr Tyr Leu Thr 
                325                 330                 335     


Ala Gly Gln Leu Ala Gly Asn Ser Ser Val Glu Met Tyr Arg Gln Val 
            340                 345                 350         


Leu Leu Ser Gly Cys Arg Cys Val Glu Leu Asp Cys Trp Lys Gly Arg 
        355                 360                 365             


Thr Ala Glu Glu Glu Pro Val Ile Thr His Gly Phe Thr Met Thr Thr 
    370                 375                 380                 


Glu Ile Ser Phe Lys Glu Val Ile Glu Ala Ile Ala Glu Cys Ala Phe 
385                 390                 395                 400 


Lys Thr Ser Pro Phe Pro Ile Leu Leu Ser Phe Glu Asn His Val Asp 
                405                 410                 415     


Ser Pro Lys Gln Gln Ala Lys Met Ala Glu Tyr Cys Arg Leu Ile Phe 
            420                 425                 430         


Gly Asp Ala Leu Leu Met Glu Pro Leu Glu Lys Tyr Pro Leu Glu Ser 
        435                 440                 445             


Gly Val Pro Leu Pro Ser Pro Met Asp Leu Met Tyr Lys Ile Leu Val 
    450                 455                 460                 


Lys Asn Lys Lys Lys Ser His Lys Ser Ser Glu Gly Ser Gly Lys Lys 
465                 470                 475                 480 


Lys Leu Ser Glu Gln Ala Ser Asn Thr Tyr Ser Asp Ser Ser Ser Met 
                485                 490                 495     


Phe Glu Pro Ser Ser Pro Gly Ala Gly Glu Ala Asp Thr Glu Ser Asp 
            500                 505                 510         


Asp Asp Asp Asp Asp Asp Asp Cys Lys Lys Ser Ser Met Asp Glu Gly 
        515                 520                 525             


Thr Ala Gly Ser Glu Ala Met Ala Thr Glu Glu Met Ser Asn Leu Val 
    530                 535                 540                 


Asn Tyr Ile Gln Pro Val Lys Phe Glu Ser Phe Glu Ile Ser Lys Lys 
545                 550                 555                 560 


Arg Asn Lys Ser Phe Glu Met Ser Ser Phe Val Glu Thr Lys Gly Leu 
                565                 570                 575     


Glu Gln Leu Thr Lys Ser Pro Val Glu Phe Val Glu Tyr Asn Lys Met 
            580                 585                 590         


Gln Leu Ser Arg Ile Tyr Pro Lys Gly Thr Arg Val Asp Ser Ser Asn 
        595                 600                 605             


Tyr Met Pro Gln Leu Phe Trp Asn Ala Gly Cys Gln Met Val Ala Leu 
    610                 615                 620                 


Asn Phe Gln Thr Met Asp Leu Ala Met Gln Ile Asn Met Gly Met Tyr 
625                 630                 635                 640 


Glu Tyr Asn Gly Lys Ser Gly Tyr Arg Leu Lys Pro Glu Phe Met Arg 
                645                 650                 655     


Arg Pro Asp Lys His Phe Asp Pro Phe Thr Glu Gly Ile Val Asp Gly 
            660                 665                 670         


Ile Val Ala Asn Thr Leu Ser Val Lys Ile Ile Ser Gly Gln Phe Leu 
        675                 680                 685             


Ser Asp Lys Lys Val Gly Thr Tyr Val Glu Val Asp Met Phe Gly Leu 
    690                 695                 700                 


Pro Val Asp Thr Arg Arg Lys Ala Phe Lys Thr Lys Thr Ser Gln Gly 
705                 710                 715                 720 


Asn Ala Val Asn Pro Val Trp Glu Glu Glu Pro Ile Val Phe Lys Lys 
                725                 730                 735     


Val Val Leu Pro Thr Leu Ala Cys Leu Arg Ile Ala Val Tyr Glu Glu 
            740                 745                 750         


Gly Gly Lys Phe Ile Gly His Arg Ile Leu Pro Val Gln Ala Ile Arg 
        755                 760                 765             


Pro Gly Tyr His Tyr Ile Cys Leu Arg Asn Glu Arg Asn Gln Pro Leu 
    770                 775                 780                 


Thr Leu Pro Ala Val Phe Val Tyr Ile Glu Val Lys Asp Tyr Val Pro 
785                 790                 795                 800 


Asp Thr Tyr Ala Asp Val Ile Glu Ala Leu Ser Asn Pro Ile Arg Tyr 
                805                 810                 815     


Val Asn Leu Met Glu Gln Arg Ala Lys Gln Leu Ala Ala Leu Thr Leu 
            820                 825                 830         


Glu Asp Glu Glu Glu Val Lys Lys Glu Ala Asp Pro Gly Glu Thr Pro 
        835                 840                 845             


Ser Glu Ala Pro Ser Glu Ala Arg Thr Thr Pro Ala Glu Asn Gly Val 
    850                 855                 860                 


Asn His Thr Thr Thr Leu Thr Pro Lys Pro Pro Ser Gln Ala Leu His 
865                 870                 875                 880 


Ser Gln Pro Ala Pro Gly Ser Val Lys Ala Pro Ala Lys Thr Glu Asp 
                885                 890                 895     


Leu Ile Gln Ser Val Leu Thr Glu Val Glu Ala Gln Thr Ile Glu Glu 
            900                 905                 910         


Leu Lys Gln Gln Lys Ser Phe Val Lys Leu Gln Lys Lys His Tyr Lys 
        915                 920                 925             


Glu Met Lys Asp Leu Val Lys Arg His His Lys Lys Thr Thr Asp Leu 
    930                 935                 940                 


Ile Lys Glu His Thr Thr Lys Tyr Asn Glu Ile Gln Asn Asp Tyr Leu 
945                 950                 955                 960 


Arg Arg Arg Ala Ala Leu Glu Lys Ser Ala Lys Lys Asp Ser Lys Lys 
                965                 970                 975     


Lys Ser Glu Pro Ser Ser Pro Asp His Gly Ser Ser Thr Ile Glu Gln 
            980                 985                 990         


Asp Leu Ala Ala Leu Asp Ala Glu  Met Thr Gln Lys Leu  Ile Asp Leu 
        995                 1000                 1005             


Lys Asp  Lys Gln Gln Gln Gln  Leu Leu Asn Leu Arg  Gln Glu Gln 
    1010                 1015                 1020             


Tyr Tyr  Ser Glu Lys Tyr Gln  Lys Arg Glu His Ile  Lys Leu Leu 
    1025                 1030                 1035             


Ile Gln  Lys Leu Thr Asp Val  Ala Glu Glu Cys Gln  Asn Asn Gln 
    1040                 1045                 1050             


Leu Lys  Lys Leu Lys Glu Ile  Cys Glu Lys Glu Lys  Lys Glu Leu 
    1055                 1060                 1065             


Lys Lys  Lys Met Asp Lys Lys  Arg Gln Glu Lys Ile  Thr Glu Ala 
    1070                 1075                 1080             


Lys Ser  Lys Asp Lys Ser Gln  Met Glu Glu Glu Lys  Thr Glu Met 
    1085                 1090                 1095             


Ile Arg  Ser Tyr Ile Gln Glu  Val Val Gln Tyr Ile  Lys Arg Leu 
    1100                 1105                 1110             


Glu Glu  Ala Gln Ser Lys Arg  Gln Glu Lys Leu Val  Glu Lys His 
    1115                 1120                 1125             


Lys Glu  Ile Arg Gln Gln Ile  Leu Asp Glu Lys Pro  Lys Gly Glu 
    1130                 1135                 1140             


Gly Ser  Ser Ser Phe Leu Ser  Glu Thr Cys His Glu  Asp Pro Ser 
    1145                 1150                 1155             


Val Ser  Pro Asn Phe Thr Pro  Pro Asn Pro Gln Ala  Leu Lys Trp 
    1160                 1165                 1170             


<210>  4099
<211>  172
<212>  PRT
<213>  homo sapiens

<400>  4099

Met Ser Val Pro Gly Pro Ser Ser Pro Asp Gly Ala Leu Thr Arg Pro 
1               5                   10                  15      


Pro Tyr Cys Leu Glu Ala Gly Glu Pro Thr Pro Gly Leu Ser Asp Thr 
            20                  25                  30          


Ser Pro Asp Glu Gly Leu Ile Glu Asp Leu Thr Ile Glu Asp Lys Ala 
        35                  40                  45              


Val Glu Gln Leu Ala Glu Gly Leu Leu Ser His Tyr Leu Pro Asp Leu 
    50                  55                  60                  


Gln Arg Ser Lys Gln Ala Leu Gln Glu Leu Thr Gln Asn Gln Val Val 
65                  70                  75                  80  


Leu Leu Asp Thr Leu Glu Gln Glu Ile Ser Lys Phe Lys Glu Cys His 
                85                  90                  95      


Ser Met Leu Asp Ile Asn Ala Leu Phe Ala Glu Ala Lys His Tyr His 
            100                 105                 110         


Ala Lys Leu Val Asn Ile Arg Lys Glu Met Leu Met Leu His Glu Lys 
        115                 120                 125             


Thr Ser Lys Leu Lys Lys Arg Ala Leu Lys Leu Gln Gln Lys Arg Gln 
    130                 135                 140                 


Lys Glu Glu Leu Glu Arg Glu Gln Gln Arg Glu Lys Glu Phe Glu Arg 
145                 150                 155                 160 


Glu Lys Gln Leu Thr Ala Arg Pro Ala Lys Arg Met 
                165                 170         


<210>  4100
<211>  290
<212>  PRT
<213>  homo sapiens

<400>  4100

Met Trp Met His Val Ala Lys Val His Pro Lys Gly Gly Glu Met Val 
1               5                   10                  15      


Gly Ala Ile Arg Asn Ala Ala Phe Leu Ala Lys Pro Ser Ile Pro Gln 
            20                  25                  30          


Val Pro Asn Tyr Arg Leu Ser Met Thr Ile Pro Asp Trp Leu Gln Ala 
        35                  40                  45              


Ile Gln Asn Tyr Met Lys Thr Leu Gln Tyr Asn His Thr Gly Thr Gln 
    50                  55                  60                  


Phe Phe Glu Ile Arg Lys Met Arg Pro Leu Ser Gly Leu Met Glu Thr 
65                  70                  75                  80  


Ala Lys Glu Met Thr Arg Glu Ser Leu Pro Ile Lys Cys Leu Glu Ala 
                85                  90                  95      


Val Ile Leu Gly Ile Tyr Leu Thr Asn Gly Gln Pro Ser Ile Glu Arg 
            100                 105                 110         


Phe Pro Ile Ser Phe Lys Thr Tyr Phe Ser Gly Asn Tyr Phe His His 
        115                 120                 125             


Val Val Leu Gly Ile Tyr Cys Asn Gly Arg Tyr Gly Ser Leu Gly Met 
    130                 135                 140                 


Ser Arg Arg Ala Glu Leu Met Asp Lys Pro Leu Thr Phe Arg Thr Leu 
145                 150                 155                 160 


Ser Asp Leu Ile Phe Asp Phe Glu Asp Ser Tyr Lys Lys Tyr Leu His 
                165                 170                 175     


Thr Val Lys Lys Val Lys Ile Gly Leu Tyr Val Pro His Glu Pro His 
            180                 185                 190         


Ser Phe Gln Pro Ile Glu Trp Lys Gln Leu Val Leu Asn Val Ser Lys 
        195                 200                 205             


Met Leu Arg Ala Asp Ile Arg Lys Glu Leu Glu Lys Tyr Ala Arg Asp 
    210                 215                 220                 


Met Arg Met Lys Ile Leu Lys Pro Ala Ser Ala His Ser Pro Thr Gln 
225                 230                 235                 240 


Val Arg Ser Arg Gly Lys Ser Leu Ser Pro Arg Arg Arg Gln Ala Ser 
                245                 250                 255     


Pro Pro Arg Arg Leu Gly Arg Arg Glu Lys Ser Pro Ala Leu Pro Glu 
            260                 265                 270         


Lys Lys Val Ala Asp Leu Ser Thr Leu Asn Glu Val Gly Tyr Gln Ile 
        275                 280                 285             


Arg Ile 
    290 


<210>  4101
<211>  251
<212>  PRT
<213>  homo sapiens

<400>  4101

Met Thr Ile Pro Asp Trp Leu Gln Ala Ile Gln Asn Tyr Met Lys Thr 
1               5                   10                  15      


Leu Gln Tyr Asn His Thr Gly Thr Gln Phe Phe Glu Ile Arg Lys Met 
            20                  25                  30          


Arg Pro Leu Ser Gly Leu Met Glu Thr Ala Lys Glu Met Thr Arg Glu 
        35                  40                  45              


Ser Leu Pro Ile Lys Cys Leu Glu Ala Val Ile Leu Gly Ile Tyr Leu 
    50                  55                  60                  


Thr Asn Gly Gln Pro Ser Ile Glu Arg Phe Pro Ile Ser Phe Lys Thr 
65                  70                  75                  80  


Tyr Phe Ser Gly Asn Tyr Phe His His Val Val Leu Gly Ile Tyr Cys 
                85                  90                  95      


Asn Gly Arg Tyr Gly Ser Leu Gly Met Ser Arg Arg Ala Glu Leu Met 
            100                 105                 110         


Asp Lys Pro Leu Thr Phe Arg Thr Leu Ser Asp Leu Ile Phe Asp Phe 
        115                 120                 125             


Glu Asp Ser Tyr Lys Lys Tyr Leu His Thr Val Lys Lys Val Lys Ile 
    130                 135                 140                 


Gly Leu Tyr Val Pro His Glu Pro His Ser Phe Gln Pro Ile Glu Trp 
145                 150                 155                 160 


Lys Gln Leu Val Leu Asn Val Ser Lys Met Leu Arg Ala Asp Ile Arg 
                165                 170                 175     


Lys Glu Leu Glu Lys Tyr Ala Arg Asp Met Arg Met Lys Ile Leu Lys 
            180                 185                 190         


Pro Ala Ser Ala His Ser Pro Thr Gln Val Arg Ser Arg Gly Lys Ser 
        195                 200                 205             


Leu Ser Pro Arg Arg Arg Gln Ala Ser Pro Pro Arg Arg Leu Gly Arg 
    210                 215                 220                 


Arg Glu Lys Ser Pro Ala Leu Pro Glu Lys Lys Val Ala Asp Leu Ser 
225                 230                 235                 240 


Thr Leu Asn Glu Val Gly Tyr Gln Ile Arg Ile 
                245                 250     


<210>  4102
<211>  287
<212>  PRT
<213>  homo sapiens

<400>  4102

Met Pro Ile Phe Thr Phe Leu Ser Glu Gln Gly Thr Leu Lys Leu Pro 
1               5                   10                  15      


Glu Lys Arg Thr Asn Gly Leu Arg Arg Thr Pro Lys Gln Val Asp Pro 
            20                  25                  30          


Gly Leu Pro Lys Met Gln Val Ile Arg Asn Tyr Ser Gly Thr Pro Pro 
        35                  40                  45              


Pro Ala Leu His Glu Gly Pro Pro Leu Gln Leu Gln Ala Gly Asp Thr 
    50                  55                  60                  


Val Glu Leu Leu Lys Gly Asp Ala His Ser Leu Phe Trp Gln Gly Arg 
65                  70                  75                  80  


Asn Leu Ala Ser Gly Glu Val Gly Phe Phe Pro Ser Asp Ala Val Lys 
                85                  90                  95      


Pro Cys Pro Cys Val Pro Lys Pro Val Asp Tyr Ser Cys Gln Pro Trp 
            100                 105                 110         


Tyr Ala Gly Ala Met Glu Arg Leu Gln Ala Glu Thr Glu Leu Ile Asn 
        115                 120                 125             


Arg Val Asn Ser Thr Tyr Leu Val Arg His Arg Thr Lys Glu Ser Gly 
    130                 135                 140                 


Glu Tyr Ala Ile Ser Ile Lys Tyr Asn Asn Glu Ala Lys His Ile Lys 
145                 150                 155                 160 


Ile Leu Thr Arg Asp Gly Phe Phe His Ile Ala Glu Asn Arg Lys Phe 
                165                 170                 175     


Lys Ser Leu Met Glu Leu Val Glu Tyr Tyr Lys His His Ser Leu Lys 
            180                 185                 190         


Glu Gly Phe Arg Thr Leu Asp Thr Thr Leu Gln Phe Pro Tyr Lys Glu 
        195                 200                 205             


Pro Glu His Ser Ala Gly Gln Arg Gly Asn Arg Ala Gly Asn Ser Leu 
    210                 215                 220                 


Leu Ser Pro Lys Val Leu Gly Ile Ala Ile Ala Arg Tyr Asp Phe Cys 
225                 230                 235                 240 


Ala Arg Asp Met Arg Glu Leu Ser Leu Leu Lys Gly Asp Val Val Lys 
                245                 250                 255     


Ile Tyr Thr Lys Met Ser Ala Asn Gly Trp Trp Arg Gly Glu Val Asn 
            260                 265                 270         


Gly Arg Val Gly Trp Phe Pro Ser Thr Tyr Val Glu Glu Asp Glu 
        275                 280                 285         


<210>  4103
<211>  2715
<212>  PRT
<213>  homo sapiens

<400>  4103

Met Lys Met Lys Ile Gln Lys Lys Glu Lys Gln Leu Ser Asn Leu Lys 
1               5                   10                  15      


Val Leu Asn His Ser Pro Met Ser Asp Ala Ser Val Asn Phe Asp Tyr 
            20                  25                  30          


Lys Ser Pro Ser Pro Phe Asp Cys Ser Thr Asp Gln Glu Glu Lys Ile 
        35                  40                  45              


Glu Asp Val Ala Ser His Cys Leu Pro Gln Lys Asp Leu Tyr Thr Ala 
    50                  55                  60                  


Glu Glu Glu Ala Ala Thr Leu Phe Pro Arg Lys Met Thr Ser His Asn 
65                  70                  75                  80  


Gly Met Glu Asp Ser Gly Gly Gly Gly Thr Gly Val Lys Lys Lys Arg 
                85                  90                  95      


Lys Lys Lys Glu Pro Gly Asp Gln Glu Gly Ala Ala Lys Gly Ser Lys 
            100                 105                 110         


Asp Arg Glu Pro Lys Pro Lys Arg Lys Arg Glu Pro Lys Glu Pro Lys 
        115                 120                 125             


Glu Pro Arg Lys Ala Lys Glu Pro Lys Lys Ala Lys Glu His Lys Glu 
    130                 135                 140                 


Pro Lys Gln Lys Asp Gly Ala Lys Lys Ala Arg Lys Pro Arg Glu Ala 
145                 150                 155                 160 


Ser Gly Thr Lys Glu Ala Lys Glu Lys Arg Ser Cys Thr Asp Ser Ala 
                165                 170                 175     


Ala Arg Thr Lys Ser Arg Lys Ala Ser Lys Glu Gln Gly Pro Thr Pro 
            180                 185                 190         


Val Glu Lys Lys Lys Lys Gly Lys Arg Lys Ser Glu Thr Thr Val Glu 
        195                 200                 205             


Ser Leu Glu Leu Asp Gln Gly Leu Thr Asn Pro Ser Leu Arg Ser Pro 
    210                 215                 220                 


Glu Glu Ser Thr Glu Ser Thr Asp Ser Gln Lys Arg Arg Ser Gly Arg 
225                 230                 235                 240 


Gln Val Lys Arg Arg Lys Tyr Asn Glu Asp Leu Asp Phe Lys Val Val 
                245                 250                 255     


Asp Asp Asp Gly Glu Thr Ile Ala Val Leu Gly Ala Gly Arg Thr Ser 
            260                 265                 270         


Ala Leu Ser Ala Ser Thr Leu Ala Trp Gln Ala Glu Glu Pro Pro Glu 
        275                 280                 285             


Asp Asp Ala Asn Ile Ile Glu Lys Ile Leu Ala Ser Lys Thr Val Gln 
    290                 295                 300                 


Glu Val His Pro Gly Glu Pro Pro Phe Asp Leu Glu Leu Phe Tyr Val 
305                 310                 315                 320 


Lys Tyr Arg Asn Phe Ser Tyr Leu His Cys Lys Trp Ala Thr Met Glu 
                325                 330                 335     


Glu Leu Glu Lys Asp Pro Arg Ile Ala Gln Lys Ile Lys Arg Phe Arg 
            340                 345                 350         


Asn Lys Gln Ala Gln Met Lys His Ile Phe Thr Glu Pro Asp Glu Asp 
        355                 360                 365             


Leu Phe Asn Pro Asp Tyr Val Glu Val Asp Arg Ile Leu Glu Val Ala 
    370                 375                 380                 


His Thr Lys Asp Ala Glu Thr Gly Glu Glu Val Thr His Tyr Leu Val 
385                 390                 395                 400 


Lys Trp Cys Ser Leu Pro Tyr Glu Glu Ser Thr Trp Glu Leu Glu Glu 
                405                 410                 415     


Asp Val Asp Pro Ala Lys Val Lys Glu Phe Glu Ser Leu Gln Val Leu 
            420                 425                 430         


Pro Glu Ile Lys His Val Glu Arg Pro Ala Ser Asp Ser Trp Gln Lys 
        435                 440                 445             


Leu Glu Lys Ser Arg Glu Tyr Lys Asn Ser Asn Gln Leu Arg Glu Tyr 
    450                 455                 460                 


Gln Leu Glu Gly Met Asn Trp Leu Leu Phe Asn Trp Tyr Asn Arg Lys 
465                 470                 475                 480 


Asn Cys Ile Leu Ala Asp Glu Met Gly Leu Gly Lys Thr Ile Gln Ser 
                485                 490                 495     


Ile Thr Phe Leu Ser Glu Ile Phe Leu Arg Gly Ile His Gly Pro Phe 
            500                 505                 510         


Leu Ile Ile Ala Pro Leu Ser Thr Ile Thr Asn Trp Glu Arg Glu Phe 
        515                 520                 525             


Arg Thr Trp Thr Glu Met Asn Ala Ile Val Tyr His Gly Ser Gln Ile 
    530                 535                 540                 


Ser Arg Gln Met Ile Gln Gln Tyr Glu Met Val Tyr Arg Asp Ala Gln 
545                 550                 555                 560 


Gly Asn Pro Leu Ser Gly Val Phe Lys Phe His Val Val Ile Thr Thr 
                565                 570                 575     


Phe Glu Met Ile Leu Ala Asp Cys Pro Glu Leu Lys Lys Ile His Trp 
            580                 585                 590         


Ser Cys Val Ile Ile Asp Glu Ala His Arg Leu Lys Asn Arg Asn Cys 
        595                 600                 605             


Lys Leu Leu Glu Gly Leu Lys Leu Met Ala Leu Glu His Lys Val Leu 
    610                 615                 620                 


Leu Thr Gly Thr Pro Leu Gln Asn Ser Val Glu Glu Leu Phe Ser Leu 
625                 630                 635                 640 


Leu Asn Phe Leu Glu Pro Ser Gln Phe Pro Ser Glu Thr Ala Phe Leu 
                645                 650                 655     


Glu Glu Phe Gly Asp Leu Lys Thr Glu Glu Gln Val Lys Lys Leu Gln 
            660                 665                 670         


Ser Ile Leu Lys Pro Met Met Leu Arg Arg Leu Lys Asp Asp Val Glu 
        675                 680                 685             


Lys Asn Leu Ala Pro Lys Gln Glu Thr Ile Ile Glu Val Glu Leu Thr 
    690                 695                 700                 


Asn Ile Gln Lys Lys Tyr Tyr Arg Ala Ile Leu Glu Lys Asn Phe Ser 
705                 710                 715                 720 


Phe Leu Thr Lys Gly Ala Asn Gln His Asn Met Pro Asn Leu Ile Asn 
                725                 730                 735     


Thr Met Met Glu Leu Arg Lys Cys Cys Asn His Pro Tyr Leu Ile Asn 
            740                 745                 750         


Gly Ala Glu Glu Lys Ile Leu Glu Asp Phe Arg Lys Thr His Ser Pro 
        755                 760                 765             


Asp Ala Pro Asp Phe Gln Leu Gln Ala Met Ile Gln Ala Ala Gly Lys 
    770                 775                 780                 


Leu Val Leu Ile Asp Lys Leu Leu Pro Lys Leu Ile Ala Gly Gly His 
785                 790                 795                 800 


Lys Val Leu Ile Phe Ser Gln Met Val Arg Cys Leu Asp Ile Leu Glu 
                805                 810                 815     


Asp Tyr Leu Ile Gln Arg Arg Tyr Thr Tyr Glu Arg Ile Asp Gly Arg 
            820                 825                 830         


Val Arg Gly Asn Leu Arg Gln Ala Ala Ile Asp Arg Phe Cys Lys Pro 
        835                 840                 845             


Asp Ser Asp Arg Phe Val Phe Leu Leu Cys Thr Arg Ala Gly Gly Leu 
    850                 855                 860                 


Gly Ile Asn Leu Thr Ala Ala Asp Thr Cys Ile Ile Phe Asp Ser Asp 
865                 870                 875                 880 


Trp Asn Pro Gln Asn Asp Leu Gln Ala Gln Ala Arg Cys His Arg Ile 
                885                 890                 895     


Gly Gln Ser Lys Ala Val Lys Val Tyr Arg Leu Ile Thr Arg Asn Ser 
            900                 905                 910         


Tyr Glu Arg Glu Met Phe Asp Lys Ala Ser Leu Lys Leu Gly Leu Asp 
        915                 920                 925             


Lys Ala Val Leu Gln Asp Ile Asn Arg Lys Gly Gly Thr Asn Gly Val 
    930                 935                 940                 


Gln Gln Leu Ser Lys Met Glu Val Glu Asp Leu Leu Arg Lys Gly Ala 
945                 950                 955                 960 


Tyr Gly Ala Leu Met Asp Glu Glu Asp Glu Gly Ser Lys Phe Cys Glu 
                965                 970                 975     


Glu Asp Ile Asp Gln Ile Leu Gln Arg Arg Thr His Thr Ile Thr Ile 
            980                 985                 990         


Gln Ser Glu Gly Lys Gly Ser Thr  Phe Ala Lys Ala Ser  Phe Val Ala 
        995                 1000                 1005             


Ser Gly  Asn Arg Thr Asp Ile  Ser Leu Asp Asp Pro  Asn Phe Trp 
    1010                 1015                 1020             


Gln Lys  Trp Ala Lys Ile Ala  Glu Leu Asp Thr Glu  Ala Lys Asn 
    1025                 1030                 1035             


Glu Lys  Glu Ser Leu Val Ile  Asp Arg Pro Arg Val  Arg Lys Gln 
    1040                 1045                 1050             


Thr Lys  His Tyr Asn Ser Phe  Glu Glu Asp Glu Leu  Met Glu Phe 
    1055                 1060                 1065             


Ser Glu  Leu Asp Ser Asp Ser  Asp Glu Arg Pro Thr  Arg Ser Arg 
    1070                 1075                 1080             


Arg Leu  Asn Asp Lys Ala Arg  Arg Tyr Leu Arg Ala  Glu Cys Phe 
    1085                 1090                 1095             


Arg Val  Glu Lys Asn Leu Leu  Ile Phe Gly Trp Gly  Arg Trp Lys 
    1100                 1105                 1110             


Asp Ile  Leu Thr His Gly Arg  Phe Lys Trp His Leu  Asn Glu Lys 
    1115                 1120                 1125             


Asp Met  Glu Met Ile Cys Arg  Ala Leu Leu Val Tyr  Cys Val Lys 
    1130                 1135                 1140             


His Tyr  Lys Gly Asp Glu Lys  Ile Lys Ser Phe Ile  Trp Glu Leu 
    1145                 1150                 1155             


Ile Thr  Pro Thr Lys Asp Gly  Gln Ala Gln Thr Leu  Gln Asn His 
    1160                 1165                 1170             


Ser Gly  Leu Ser Ala Pro Val  Pro Arg Gly Arg Lys  Gly Lys Lys 
    1175                 1180                 1185             


Thr Lys  Asn Gln Leu Leu Ile  Pro Glu Leu Lys Asp  Ala Asp Trp 
    1190                 1195                 1200             


Leu Ala  Thr Cys Asn Pro Glu  Val Val Leu His Asp  Asp Gly Tyr 
    1205                 1210                 1215             


Lys Lys  His Leu Lys Gln His  Cys Asn Lys Val Leu  Leu Arg Val 
    1220                 1225                 1230             


Arg Met  Leu Tyr Tyr Leu Lys  Ala Glu Ile Leu Gly  Glu Ala Ala 
    1235                 1240                 1245             


Glu Lys  Ala Phe Glu Gly Ser  Pro Ala Arg Glu Leu  Asp Val Pro 
    1250                 1255                 1260             


Leu Pro  Asp Ile Asp Tyr Met  Glu Ile Pro Val Asp  Trp Trp Asp 
    1265                 1270                 1275             


Ala Glu  Ala Asp Lys Ser Leu  Leu Ile Gly Val Phe  Lys His Gly 
    1280                 1285                 1290             


Tyr Glu  Arg Tyr Asn Ala Met  Arg Ala Asp Pro Ala  Leu Cys Phe 
    1295                 1300                 1305             


Leu Glu  Lys Val Gly Met Pro  Asp Glu Lys Ser Leu  Ser Ala Glu 
    1310                 1315                 1320             


Gln Gly  Val Thr Asp Gly Thr  Ser Asp Ile Pro Glu  Arg Gly Asn 
    1325                 1330                 1335             


Thr Asp  Lys Glu Asp Asn Ala  Glu Asp Lys Val Asp  Gly Leu Gln 
    1340                 1345                 1350             


Lys Gln  Thr Glu Ser Ser Ser  Asp Gly Gly Asp Gly  Val Phe Ser 
    1355                 1360                 1365             


Glu Lys  Lys Asp Asp Ser Arg  Ala Ala Gln Asp Gly  Ser Asp Pro 
    1370                 1375                 1380             


Asp Lys  Ser Pro Trp Pro Val  Ser Ser Ala Leu Thr  Ala Arg Leu 
    1385                 1390                 1395             


Arg Arg  Leu Val Thr Val Tyr  Gln Arg Cys Asn Arg  Lys Glu Leu 
    1400                 1405                 1410             


Cys Arg  Pro Glu Ile Leu Gly  Pro Gly Asn Gln Gly  Tyr Trp Val 
    1415                 1420                 1425             


Gln Glu  Glu Met Phe Arg Arg  Thr Ser Glu Met Asp  Leu Ile Asn 
    1430                 1435                 1440             


Lys Glu  Ala Gln Lys Arg Trp  Thr Arg Arg Glu Gln  Ala Asp Phe 
    1445                 1450                 1455             


Tyr Arg  Thr Val Ser Ser Phe  Gly Val Val Tyr Asp  Gln Glu Lys 
    1460                 1465                 1470             


Lys Thr  Phe Asp Trp Thr Gln  Phe Arg Ile Ile Ser  Arg Leu Asp 
    1475                 1480                 1485             


Lys Lys  Ser Asp Glu Ser Leu  Glu Gln Tyr Phe Tyr  Ser Phe Val 
    1490                 1495                 1500             


Ala Met  Cys Arg Asn Val Cys  Arg Leu Pro Thr Trp  Lys Asp Gly 
    1505                 1510                 1515             


Gly Pro  Pro Asp Thr Thr Ile  Tyr Val Glu Pro Ile  Thr Glu Glu 
    1520                 1525                 1530             


Arg Ala  Ala Arg Thr Leu Tyr  Arg Ile Glu Leu Leu  Arg Lys Val 
    1535                 1540                 1545             


Arg Glu  Gln Val Leu Lys Cys  Pro Gln Leu His Glu  Arg Leu Gln 
    1550                 1555                 1560             


Leu Cys  Arg Pro Ser Leu Tyr  Leu Pro Val Trp Trp  Glu Cys Gly 
    1565                 1570                 1575             


Lys His  Asp Arg Asp Leu Leu  Ile Gly Thr Ala Lys  His Gly Leu 
    1580                 1585                 1590             


Asn Arg  Thr Asp Cys Tyr Ile  Met Asn Asp Pro Gln  Leu Ser Phe 
    1595                 1600                 1605             


Leu Asp  Ala Tyr Arg Asn Tyr  Ala Gln His Lys Arg  Ser Gly Thr 
    1610                 1615                 1620             


Gln Ala  Pro Gly Asn Leu Cys  Cys Leu Tyr Gln Thr  Asn Ser Lys 
    1625                 1630                 1635             


Leu Tyr  Glu Ser Leu Thr Tyr  Ser Gln Met Ser Arg  Thr Ser Glu 
    1640                 1645                 1650             


Ser Leu  Glu Asn Glu Pro Glu  Asn Leu Val Arg Val  Glu Ser Arg 
    1655                 1660                 1665             


Asp Asp  His Leu Ser Leu Pro  Asp Val Thr Cys Glu  Asn Phe Ile 
    1670                 1675                 1680             


Ser Lys  Val Gln Asp Val Ile  Ser Ile Asn His Asp  Glu Ser Leu 
    1685                 1690                 1695             


Leu Pro  Glu Ser Leu Glu Ser  Met Met Tyr Gly Lys  Lys Val Leu 
    1700                 1705                 1710             


Ser Gln  Glu Pro Ser Ser Phe  Gln Glu Ser Pro Ser  Thr Asn Thr 
    1715                 1720                 1725             


Glu Ser  Arg Lys Asp Val Ile  Thr Ile Ser Ile Ser  Lys Asp Gly 
    1730                 1735                 1740             


Asn Cys  Gln Ser Gly Gly Pro  Glu Ala Glu Ile Ala  Ser Gly Pro 
    1745                 1750                 1755             


Thr Phe  Met Gly Ser Leu Glu  Ala Gly Gly Val Ala  Gln Ala Asn 
    1760                 1765                 1770             


Ile Lys  Asn Gly Lys His Leu  Leu Met Ser Ile Ser  Lys Glu Gly 
    1775                 1780                 1785             


Glu Leu  Cys Cys Ser Glu Ala  Gly Gln Arg Pro Glu  Asn Ile Gly 
    1790                 1795                 1800             


Gln Leu  Glu Ala Lys Cys Leu  Ala Ser Pro Ser Leu  Asn Pro Gly 
    1805                 1810                 1815             


Asn Glu  Ser Gly Phe Val Asp  Met Cys Ser Leu Ser  Val Cys Asp 
    1820                 1825                 1830             


Ser Lys  Arg Asn Leu Ser Ser  Asp Gln Gln Leu Ile  Asp Leu Leu 
    1835                 1840                 1845             


Glu Asn  Lys Ser Leu Glu Ser  Lys Leu Ile Leu Ser  Gln Asn His 
    1850                 1855                 1860             


Ser Asp  Glu Glu Glu Glu Glu  Glu Glu Asn Glu Glu  Glu Asn Leu 
    1865                 1870                 1875             


Ala Met  Ala Val Gly Met Gly  Glu Arg Pro Glu Val  Leu His Leu 
    1880                 1885                 1890             


Thr Glu  Pro Thr Thr Asn Ile  Ser Arg Glu Lys Asn  Gln Gly Phe 
    1895                 1900                 1905             


Gln Asp  Glu Thr Lys Lys Gly  Ser Leu Glu Val Ala  Asn Gln Thr 
    1910                 1915                 1920             


Pro Gly  Leu Gln Arg Ala Phe  Pro Ala Pro Ala Ala  Cys Gln Cys 
    1925                 1930                 1935             


His Cys  Lys His Met Glu Arg  Trp Met His Gly Leu  Glu Asn Asp 
    1940                 1945                 1950             


Glu Phe  Glu Ile Glu Lys Pro  Lys Ala Tyr Ile Pro  Asp Leu Phe 
    1955                 1960                 1965             


Lys Ser  Lys Thr Asn Thr Ile  Ala Met Glu Gly Glu  Pro Thr Ala 
    1970                 1975                 1980             


Ile Pro  Ser Gln Pro Phe Lys  Val Lys His Glu Leu  Leu Lys Glu 
    1985                 1990                 1995             


Pro Trp  Lys Glu Ser Ala Glu  Gly Gln Asn Val Phe  Pro Thr Tyr 
    2000                 2005                 2010             


Pro Leu  Glu Gly Ser Glu Leu  Lys Ser Glu Asp Met  Asp Phe Glu 
    2015                 2020                 2025             


Asn Lys  Asp Asp Tyr Asp Arg  Asp Gly Asn Cys His  Ser Gln Asp 
    2030                 2035                 2040             


Tyr Pro  Gly Lys Tyr Ser Glu  Glu Glu Ser Lys Ser  Ser Thr Ser 
    2045                 2050                 2055             


Gly Ile  Thr Gly Asp Ile Gly  Asp Glu Leu Gln Glu  Ala Arg Ala 
    2060                 2065                 2070             


Pro Thr  Ile Ala Gln Leu Leu  Gln Glu Lys Thr Leu  Tyr Ser Phe 
    2075                 2080                 2085             


Ser Glu  Trp Pro Lys Asp Arg  Val Ile Ile Asn Arg  Leu Asp Asn 
    2090                 2095                 2100             


Ile Cys  His Val Val Leu Lys  Gly Lys Trp Pro Ser  Ser Gln Gln 
    2105                 2110                 2115             


Tyr Glu  Pro Ser Gly Thr Leu  Pro Thr Pro Val Leu  Thr Ser Ser 
    2120                 2125                 2130             


Ala Gly  Ser Arg Thr Ser Leu  Ser Glu Pro Glu Ala  Ala Glu His 
    2135                 2140                 2145             


Ser Phe  Ser Asn Gly Ala Ala  Leu Ala Ala Gln Ile  His Lys Glu 
    2150                 2155                 2160             


Ser Phe  Leu Ala Pro Val Phe  Thr Lys Asp Glu Gln  Lys His Arg 
    2165                 2170                 2175             


Arg Pro  Tyr Glu Phe Glu Val  Glu Arg Asp Ala Lys  Ala Arg Gly 
    2180                 2185                 2190             


Leu Glu  Gln Phe Ser Ala Thr  His Gly His Thr Pro  Ile Ile Leu 
    2195                 2200                 2205             


Asn Gly  Trp His Gly Glu Ser  Ala Met Asp Leu Ser  Cys Ser Ser 
    2210                 2215                 2220             


Glu Gly  Ser Pro Gly Ala Thr  Ser Pro Phe Pro Val  Ser Ala Ser 
    2225                 2230                 2235             


Thr Pro  Lys Ile Gly Ala Ile  Ser Ser Leu Gln Gly  Ala Leu Gly 
    2240                 2245                 2250             


Met Asp  Leu Ser Gly Ile Leu  Gln Ala Gly Leu Ile  His Pro Val 
    2255                 2260                 2265             


Thr Gly  Gln Ile Val Asn Gly  Ser Leu Arg Arg Asp  Asp Ala Ala 
    2270                 2275                 2280             


Thr Arg  Arg Arg Arg Gly Arg  Arg Lys His Val Glu  Gly Gly Met 
    2285                 2290                 2295             


Asp Leu  Ile Phe Leu Lys Glu  Gln Thr Leu Gln Ala  Gly Ile Leu 
    2300                 2305                 2310             


Glu Val  His Glu Asp Pro Gly  Gln Ala Thr Leu Ser  Thr Thr His 
    2315                 2320                 2325             


Pro Glu  Gly Pro Gly Pro Ala  Thr Ser Ala Pro Glu  Pro Ala Thr 
    2330                 2335                 2340             


Ala Ala  Ser Ser Gln Ala Glu  Lys Ser Ile Pro Ser  Lys Ser Leu 
    2345                 2350                 2355             


Leu Asp  Trp Leu Arg Gln Gln  Ala Asp Tyr Ser Leu  Glu Val Pro 
    2360                 2365                 2370             


Gly Phe  Gly Ala Asn Phe Ser  Asp Lys Pro Lys Gln  Arg Arg Pro 
    2375                 2380                 2385             


Arg Cys  Lys Glu Pro Gly Lys  Leu Asp Val Ser Ser  Leu Ser Gly 
    2390                 2395                 2400             


Glu Glu  Arg Val Pro Ala Ile  Pro Lys Glu Pro Gly  Leu Arg Gly 
    2405                 2410                 2415             


Phe Leu  Pro Glu Asn Lys Phe  Asn His Thr Leu Ala  Glu Pro Ile 
    2420                 2425                 2430             


Leu Arg  Asp Thr Gly Pro Arg  Arg Arg Gly Arg Arg  Pro Arg Ser 
    2435                 2440                 2445             


Glu Leu  Leu Lys Ala Pro Ser  Ile Val Ala Asp Ser  Pro Ser Gly 
    2450                 2455                 2460             


Met Gly  Pro Leu Phe Met Asn  Gly Leu Ile Ala Gly  Met Asp Leu 
    2465                 2470                 2475             


Val Gly  Leu Gln Asn Met Arg  Asn Met Pro Gly Ile  Pro Leu Thr 
    2480                 2485                 2490             


Gly Leu  Val Gly Phe Pro Ala  Gly Phe Ala Thr Met  Pro Thr Gly 
    2495                 2500                 2505             


Glu Glu  Val Lys Ser Thr Leu  Ser Met Leu Pro Met  Met Leu Pro 
    2510                 2515                 2520             


Gly Met  Ala Ala Val Pro Gln  Met Phe Gly Val Gly  Gly Leu Leu 
    2525                 2530                 2535             


Ser Pro  Pro Met Ala Thr Thr  Cys Thr Ser Thr Ala  Pro Ala Ser 
    2540                 2545                 2550             


Leu Ser  Ser Thr Thr Lys Ser  Gly Thr Ala Val Thr  Glu Lys Thr 
    2555                 2560                 2565             


Ala Glu  Asp Lys Pro Ser Ser  His Asp Val Lys Thr  Asp Thr Leu 
    2570                 2575                 2580             


Ala Glu  Asp Lys Pro Gly Pro  Gly Pro Phe Ser Asp  Gln Ser Glu 
    2585                 2590                 2595             


Pro Ala  Ile Thr Thr Ser Ser  Pro Val Ala Phe Asn  Pro Phe Leu 
    2600                 2605                 2610             


Ile Pro  Gly Val Ser Pro Gly  Leu Ile Tyr Pro Ser  Met Phe Leu 
    2615                 2620                 2625             


Ser Pro  Gly Met Gly Met Ala  Leu Pro Ala Met Gln  Gln Ala Arg 
    2630                 2635                 2640             


His Ser  Glu Ile Val Gly Leu  Glu Ser Gln Lys Arg  Lys Lys Lys 
    2645                 2650                 2655             


Lys Thr  Lys Gly Asp Asn Pro  Asn Ser His Pro Glu  Pro Ala Pro 
    2660                 2665                 2670             


Ser Cys  Glu Arg Glu Pro Ser  Gly Asp Glu Asn Cys  Ala Glu Pro 
    2675                 2680                 2685             


Ser Ala  Pro Leu Pro Ala Glu  Arg Glu His Gly Ala  Gln Ala Gly 
    2690                 2695                 2700             


Glu Gly  Ala Leu Lys Asp Ser  Asn Asn Asp Thr Asn  
    2705                 2710                 2715 


<210>  4104
<211>  183
<212>  PRT
<213>  homo sapiens

<400>  4104

Met Thr Thr Ala Ser Thr Ser Gln Val Arg Gln Asn Tyr His Gln Asp 
1               5                   10                  15      


Ser Glu Ala Ala Ile Asn Arg Gln Ile Asn Leu Glu Leu Tyr Ala Ser 
            20                  25                  30          


Tyr Val Tyr Leu Ser Met Ser Tyr Tyr Phe Asp Arg Asp Asp Val Ala 
        35                  40                  45              


Leu Lys Asn Phe Ala Lys Tyr Phe Leu His Gln Ser His Glu Glu Arg 
    50                  55                  60                  


Glu His Ala Glu Lys Leu Met Lys Leu Gln Asn Gln Arg Gly Gly Arg 
65                  70                  75                  80  


Ile Phe Leu Gln Asp Ile Lys Lys Pro Asp Cys Asp Asp Trp Glu Ser 
                85                  90                  95      


Gly Leu Asn Ala Met Glu Cys Ala Leu His Leu Glu Lys Asn Val Asn 
            100                 105                 110         


Gln Ser Leu Leu Glu Leu His Lys Leu Ala Thr Asp Lys Asn Asp Pro 
        115                 120                 125             


His Leu Cys Asp Phe Ile Glu Thr His Tyr Leu Asn Glu Gln Val Lys 
    130                 135                 140                 


Ala Ile Lys Glu Leu Gly Asp His Val Thr Asn Leu Arg Lys Met Gly 
145                 150                 155                 160 


Ala Pro Glu Ser Gly Leu Ala Glu Tyr Leu Phe Asp Lys His Thr Leu 
                165                 170                 175     


Gly Asp Ser Asp Asn Glu Ser 
            180             


<210>  4105
<211>  572
<212>  PRT
<213>  homo sapiens

<400>  4105

Met Ala Glu Leu Val Gln Gly Gln Ser Ala Pro Val Gly Met Lys Ala 
1               5                   10                  15      


Glu Gly Phe Val Asp Ala Leu His Arg Val Arg Gln Ile Ala Ala Lys 
            20                  25                  30          


Ile Asp Ser Ile Pro His Leu Asn Asn Ser Thr Pro Leu Val Asp Pro 
        35                  40                  45              


Ser Val Tyr Gly Tyr Gly Val Gln Lys Arg Pro Leu Asp Asp Gly Val 
    50                  55                  60                  


Gly Asn Gln Leu Gly Ala Leu Val His Gln Arg Thr Val Ile Thr Glu 
65                  70                  75                  80  


Glu Phe Lys Val Pro Asp Lys Met Val Gly Phe Ile Ile Gly Arg Gly 
                85                  90                  95      


Gly Glu Gln Ile Ser Arg Ile Gln Ala Glu Ser Gly Cys Lys Ile Gln 
            100                 105                 110         


Ile Ala Ser Glu Ser Ser Gly Ile Pro Glu Arg Pro Cys Val Leu Thr 
        115                 120                 125             


Gly Thr Pro Glu Ser Ile Glu Gln Ala Lys Arg Leu Leu Gly Gln Ile 
    130                 135                 140                 


Val Asp Arg Cys Arg Asn Gly Pro Gly Phe His Asn Asp Ile Asp Ser 
145                 150                 155                 160 


Asn Ser Thr Ile Gln Glu Ile Leu Ile Pro Ala Ser Lys Val Gly Leu 
                165                 170                 175     


Val Ile Gly Arg Gly Gly Glu Thr Ile Lys Gln Leu Gln Glu Arg Thr 
            180                 185                 190         


Gly Val Lys Met Val Met Ile Gln Asp Gly Pro Leu Pro Thr Gly Ala 
        195                 200                 205             


Asp Lys Pro Leu Arg Ile Thr Gly Asp Ala Phe Lys Val Gln Gln Ala 
    210                 215                 220                 


Arg Glu Met Val Leu Glu Ile Ile Arg Glu Lys Asp Gln Ala Asp Phe 
225                 230                 235                 240 


Arg Gly Val Arg Gly Asp Phe Asn Ser Arg Met Gly Gly Gly Ser Ile 
                245                 250                 255     


Glu Val Ser Val Pro Arg Phe Ala Val Gly Ile Val Ile Gly Arg Asn 
            260                 265                 270         


Gly Glu Met Ile Lys Lys Ile Gln Asn Asp Ala Gly Val Arg Ile Gln 
        275                 280                 285             


Phe Lys Pro Asp Asp Gly Ile Ser Pro Glu Arg Ala Ala Gln Val Met 
    290                 295                 300                 


Gly Pro Pro Asp Arg Cys Gln His Ala Ala His Ile Ile Ser Glu Leu 
305                 310                 315                 320 


Ile Leu Thr Ala Gln Glu Arg Asp Gly Phe Gly Gly Leu Ala Ala Ala 
                325                 330                 335     


Arg Gly Arg Gly Arg Gly Arg Gly Asp Trp Ser Val Gly Ala Pro Gly 
            340                 345                 350         


Gly Val Gln Glu Ile Thr Tyr Thr Val Pro Ala Asp Lys Cys Gly Leu 
        355                 360                 365             


Val Ile Gly Lys Gly Gly Glu Asn Ile Lys Ser Ile Asn Gln Gln Ser 
    370                 375                 380                 


Gly Ala His Val Glu Leu Gln Arg Asn Pro Pro Pro Asn Ser Asp Pro 
385                 390                 395                 400 


Asn Leu Arg Arg Phe Thr Ile Arg Gly Val Pro Gln Gln Ile Glu Val 
                405                 410                 415     


Ala Arg Gln Leu Ile Asp Glu Lys Val Gly Gly Thr Asn Leu Gly Ala 
            420                 425                 430         


Pro Gly Ala Phe Gly Gln Ser Pro Phe Ser Gln Pro Pro Ala Pro Pro 
        435                 440                 445             


His Gln Asn Thr Phe Pro Pro Arg Ser Ser Gly Cys Phe Pro Asn Met 
    450                 455                 460                 


Ala Ala Lys Val Asn Gly Asn Pro His Ser Thr Pro Val Ser Gly Pro 
465                 470                 475                 480 


Pro Ala Phe Leu Thr Gln Gly Trp Gly Ser Thr Tyr Gln Ala Trp Gln 
                485                 490                 495     


Gln Pro Thr Gln Gln Val Pro Ser Gln Gln Ser Gln Pro Gln Ser Ser 
            500                 505                 510         


Gln Pro Asn Tyr Ser Lys Ala Trp Glu Asp Tyr Tyr Lys Lys Gln Ser 
        515                 520                 525             


His Ala Ala Ser Ala Ala Pro Gln Ala Ser Ser Pro Pro Asp Tyr Thr 
    530                 535                 540                 


Met Ala Trp Ala Glu Tyr Tyr Arg Gln Gln Val Ala Phe Tyr Gly Gln 
545                 550                 555                 560 


Thr Leu Gly Gln Ala Gln Ala His Ser Gln Glu Gln 
                565                 570         


<210>  4106
<211>  575
<212>  PRT
<213>  homo sapiens

<400>  4106

Met Arg Pro Trp Thr Gly Ser Trp Arg Trp Ile Met Leu Ile Leu Phe 
1               5                   10                  15      


Ala Trp Gly Thr Leu Leu Phe Tyr Ile Gly Gly His Leu Val Arg Asp 
            20                  25                  30          


Asn Asp His Pro Asp His Ser Ser Arg Glu Leu Ser Lys Ile Leu Ala 
        35                  40                  45              


Lys Leu Glu Arg Leu Lys Gln Gln Asn Glu Asp Leu Arg Arg Met Ala 
    50                  55                  60                  


Glu Ser Leu Arg Ile Pro Glu Gly Pro Ile Asp Gln Gly Pro Ala Ile 
65                  70                  75                  80  


Gly Arg Val Arg Val Leu Glu Glu Gln Leu Val Lys Ala Lys Glu Gln 
                85                  90                  95      


Ile Glu Asn Tyr Lys Lys Gln Thr Arg Asn Gly Leu Gly Lys Asp His 
            100                 105                 110         


Glu Ile Leu Arg Arg Arg Ile Glu Asn Gly Ala Lys Glu Leu Trp Phe 
        115                 120                 125             


Phe Leu Gln Ser Glu Leu Lys Lys Leu Lys Asn Leu Glu Gly Asn Glu 
    130                 135                 140                 


Leu Gln Arg His Ala Asp Glu Phe Leu Leu Asp Leu Gly His His Glu 
145                 150                 155                 160 


Arg Ser Ile Met Thr Asp Leu Tyr Tyr Leu Ser Gln Thr Asp Gly Ala 
                165                 170                 175     


Gly Asp Trp Arg Glu Lys Glu Ala Lys Asp Leu Thr Glu Leu Val Gln 
            180                 185                 190         


Arg Arg Ile Thr Tyr Leu Gln Asn Pro Lys Asp Cys Ser Lys Ala Lys 
        195                 200                 205             


Lys Leu Val Cys Asn Ile Asn Lys Gly Cys Gly Tyr Gly Cys Gln Leu 
    210                 215                 220                 


His His Val Val Tyr Cys Phe Met Ile Ala Tyr Gly Thr Gln Arg Thr 
225                 230                 235                 240 


Leu Ile Leu Glu Ser Gln Asn Trp Arg Tyr Ala Thr Gly Gly Trp Glu 
                245                 250                 255     


Thr Val Phe Arg Pro Val Ser Glu Thr Cys Thr Asp Arg Ser Gly Ile 
            260                 265                 270         


Ser Thr Gly His Trp Ser Gly Glu Val Lys Asp Lys Asn Val Gln Val 
        275                 280                 285             


Val Glu Leu Pro Ile Val Asp Ser Leu His Pro Arg Pro Pro Tyr Leu 
    290                 295                 300                 


Pro Leu Ala Val Pro Glu Asp Leu Ala Asp Arg Leu Val Arg Val His 
305                 310                 315                 320 


Gly Asp Pro Ala Val Trp Trp Val Ser Gln Phe Val Lys Tyr Leu Ile 
                325                 330                 335     


Arg Pro Gln Pro Trp Leu Glu Lys Glu Ile Glu Glu Ala Thr Lys Lys 
            340                 345                 350         


Leu Gly Phe Lys His Pro Val Ile Gly Val His Val Arg Arg Thr Asp 
        355                 360                 365             


Lys Val Gly Thr Glu Ala Ala Phe His Pro Ile Glu Glu Tyr Met Val 
    370                 375                 380                 


His Val Glu Glu His Phe Gln Leu Leu Ala Arg Arg Met Gln Val Asp 
385                 390                 395                 400 


Lys Lys Arg Val Tyr Leu Ala Thr Asp Asp Pro Ser Leu Leu Lys Glu 
                405                 410                 415     


Ala Lys Thr Lys Tyr Pro Asn Tyr Glu Phe Ile Ser Asp Asn Ser Ile 
            420                 425                 430         


Ser Trp Ser Ala Gly Leu His Asn Arg Tyr Thr Glu Asn Ser Leu Arg 
        435                 440                 445             


Gly Val Ile Leu Asp Ile His Phe Leu Ser Gln Ala Asp Phe Leu Val 
    450                 455                 460                 


Cys Thr Phe Ser Ser Gln Val Cys Arg Val Ala Tyr Glu Ile Met Gln 
465                 470                 475                 480 


Thr Leu His Pro Asp Ala Ser Ala Asn Phe His Ser Leu Asp Asp Ile 
                485                 490                 495     


Tyr Tyr Phe Gly Gly Gln Asn Ala His Asn Gln Ile Ala Ile Tyr Ala 
            500                 505                 510         


His Gln Pro Arg Thr Ala Asp Glu Ile Pro Met Glu Pro Gly Asp Ile 
        515                 520                 525             


Ile Gly Val Ala Gly Asn His Trp Asp Gly Tyr Ser Lys Gly Val Asn 
    530                 535                 540                 


Arg Lys Leu Gly Arg Thr Gly Leu Tyr Pro Ser Tyr Lys Val Arg Glu 
545                 550                 555                 560 


Lys Ile Glu Thr Val Lys Tyr Pro Thr Tyr Pro Glu Ala Glu Lys 
                565                 570                 575 


<210>  4107
<211>  497
<212>  PRT
<213>  homo sapiens

<400>  4107

Met Gly Arg Lys Lys Ile Gln Ile Thr Arg Ile Met Asp Glu Arg Asn 
1               5                   10                  15      


Arg Gln Val Thr Phe Thr Lys Arg Lys Phe Gly Leu Met Lys Lys Ala 
            20                  25                  30          


Tyr Glu Leu Ser Val Leu Cys Asp Cys Glu Ile Ala Leu Ile Ile Phe 
        35                  40                  45              


Asn Ser Ser Asn Lys Leu Phe Gln Tyr Ala Ser Thr Asp Met Asp Lys 
    50                  55                  60                  


Val Leu Leu Lys Tyr Thr Glu Tyr Asn Glu Pro His Glu Ser Arg Thr 
65                  70                  75                  80  


Asn Ser Asp Ile Val Glu Thr Leu Arg Lys Lys Gly Leu Asn Gly Cys 
                85                  90                  95      


Glu Ser Pro Asp Ala Asp Asp Tyr Phe Glu His Ser Pro Leu Ser Glu 
            100                 105                 110         


Asp Arg Phe Ser Lys Leu Asn Glu Asp Ser Asp Phe Ile Phe Lys Arg 
        115                 120                 125             


Gly Pro Pro Gly Leu Pro Pro Gln Asn Phe Ser Met Ser Val Thr Val 
    130                 135                 140                 


Pro Val Thr Ser Pro Asn Ala Leu Ser Tyr Thr Asn Pro Gly Ser Ser 
145                 150                 155                 160 


Leu Val Ser Pro Ser Leu Ala Ala Ser Ser Thr Leu Thr Asp Ser Ser 
                165                 170                 175     


Met Leu Ser Pro Pro Gln Thr Thr Leu His Arg Asn Val Ser Pro Gly 
            180                 185                 190         


Ala Pro Gln Arg Pro Pro Ser Thr Gly Asn Ala Gly Gly Met Leu Ser 
        195                 200                 205             


Thr Thr Asp Leu Thr Val Pro Asn Gly Ala Gly Ser Ser Pro Val Gly 
    210                 215                 220                 


Asn Gly Phe Val Asn Ser Arg Ala Ser Pro Asn Leu Ile Gly Ala Thr 
225                 230                 235                 240 


Gly Ala Asn Ser Leu Gly Lys Val Met Pro Thr Lys Ser Pro Pro Pro 
                245                 250                 255     


Pro Gly Gly Gly Asn Leu Gly Met Asn Ser Arg Lys Pro Asp Leu Arg 
            260                 265                 270         


Val Val Ile Pro Pro Ser Ser Lys Gly Met Met Pro Pro Leu Asn Thr 
        275                 280                 285             


Gln Arg Ile Ser Ser Ser Gln Ala Thr Gln Pro Leu Ala Thr Pro Val 
    290                 295                 300                 


Val Ser Val Thr Thr Pro Ser Leu Pro Pro Gln Gly Leu Val Tyr Ser 
305                 310                 315                 320 


Ala Met Pro Thr Ala Tyr Asn Thr Asp Tyr Ser Leu Thr Ser Ala Asp 
                325                 330                 335     


Leu Ser Ala Leu Gln Gly Phe Asn Ser Pro Gly Met Leu Ser Leu Gly 
            340                 345                 350         


Gln Val Ser Ala Trp Gln Gln His His Leu Gly Gln Ala Ala Leu Ser 
        355                 360                 365             


Ser Leu Val Ala Gly Gly Gln Leu Ser Gln Gly Ser Asn Leu Ser Ile 
    370                 375                 380                 


Asn Thr Asn Gln Asn Ile Ser Ile Lys Ser Glu Pro Ile Ser Pro Pro 
385                 390                 395                 400 


Arg Asp Arg Met Thr Pro Ser Gly Phe Gln Gln Gln Gln Gln Gln Gln 
                405                 410                 415     


Gln Gln Gln Gln Pro Pro Pro Pro Pro Gln Pro Gln Pro Gln Pro Pro 
            420                 425                 430         


Gln Pro Gln Pro Arg Gln Glu Met Gly Arg Ser Pro Val Asp Ser Leu 
        435                 440                 445             


Ser Ser Ser Ser Ser Ser Tyr Asp Gly Ser Asp Arg Glu Asp Pro Arg 
    450                 455                 460                 


Gly Asp Phe His Ser Pro Ile Val Leu Gly Arg Pro Pro Asn Thr Glu 
465                 470                 475                 480 


Asp Arg Glu Ser Pro Ser Val Lys Arg Met Arg Met Asp Ala Trp Val 
                485                 490                 495     


Thr 
    


<210>  4108
<211>  575
<212>  PRT
<213>  homo sapiens

<400>  4108

Met Arg Pro Trp Thr Gly Ser Trp Arg Trp Ile Met Leu Ile Leu Phe 
1               5                   10                  15      


Ala Trp Gly Thr Leu Leu Phe Tyr Ile Gly Gly His Leu Val Arg Asp 
            20                  25                  30          


Asn Asp His Pro Asp His Ser Ser Arg Glu Leu Ser Lys Ile Leu Ala 
        35                  40                  45              


Lys Leu Glu Arg Leu Lys Gln Gln Asn Glu Asp Leu Arg Arg Met Ala 
    50                  55                  60                  


Glu Ser Leu Arg Ile Pro Glu Gly Pro Ile Asp Gln Gly Pro Ala Ile 
65                  70                  75                  80  


Gly Arg Val Arg Val Leu Glu Glu Gln Leu Val Lys Ala Lys Glu Gln 
                85                  90                  95      


Ile Glu Asn Tyr Lys Lys Gln Thr Arg Asn Gly Leu Gly Lys Asp His 
            100                 105                 110         


Glu Ile Leu Arg Arg Arg Ile Glu Asn Gly Ala Lys Glu Leu Trp Phe 
        115                 120                 125             


Phe Leu Gln Ser Glu Leu Lys Lys Leu Lys Asn Leu Glu Gly Asn Glu 
    130                 135                 140                 


Leu Gln Arg His Ala Asp Glu Phe Leu Leu Asp Leu Gly His His Glu 
145                 150                 155                 160 


Arg Ser Ile Met Thr Asp Leu Tyr Tyr Leu Ser Gln Thr Asp Gly Ala 
                165                 170                 175     


Gly Asp Trp Arg Glu Lys Glu Ala Lys Asp Leu Thr Glu Leu Val Gln 
            180                 185                 190         


Arg Arg Ile Thr Tyr Leu Gln Asn Pro Lys Asp Cys Ser Lys Ala Lys 
        195                 200                 205             


Lys Leu Val Cys Asn Ile Asn Lys Gly Cys Gly Tyr Gly Cys Gln Leu 
    210                 215                 220                 


His His Val Val Tyr Cys Phe Met Ile Ala Tyr Gly Thr Gln Arg Thr 
225                 230                 235                 240 


Leu Ile Leu Glu Ser Gln Asn Trp Arg Tyr Ala Thr Gly Gly Trp Glu 
                245                 250                 255     


Thr Val Phe Arg Pro Val Ser Glu Thr Cys Thr Asp Arg Ser Gly Ile 
            260                 265                 270         


Ser Thr Gly His Trp Ser Gly Glu Val Lys Asp Lys Asn Val Gln Val 
        275                 280                 285             


Val Glu Leu Pro Ile Val Asp Ser Leu His Pro Arg Pro Pro Tyr Leu 
    290                 295                 300                 


Pro Leu Ala Val Pro Glu Asp Leu Ala Asp Arg Leu Val Arg Val His 
305                 310                 315                 320 


Gly Asp Pro Ala Val Trp Trp Val Ser Gln Phe Val Lys Tyr Leu Ile 
                325                 330                 335     


Arg Pro Gln Pro Trp Leu Glu Lys Glu Ile Glu Glu Ala Thr Lys Lys 
            340                 345                 350         


Leu Gly Phe Lys His Pro Val Ile Gly Val His Val Arg Arg Thr Asp 
        355                 360                 365             


Lys Val Gly Thr Glu Ala Ala Phe His Pro Ile Glu Glu Tyr Met Val 
    370                 375                 380                 


His Val Glu Glu His Phe Gln Leu Leu Ala Arg Arg Met Gln Val Asp 
385                 390                 395                 400 


Lys Lys Arg Val Tyr Leu Ala Thr Asp Asp Pro Ser Leu Leu Lys Glu 
                405                 410                 415     


Ala Lys Thr Lys Tyr Pro Asn Tyr Glu Phe Ile Ser Asp Asn Ser Ile 
            420                 425                 430         


Ser Trp Ser Ala Gly Leu His Asn Arg Tyr Thr Glu Asn Ser Leu Arg 
        435                 440                 445             


Gly Val Ile Leu Asp Ile His Phe Leu Ser Gln Ala Asp Phe Leu Val 
    450                 455                 460                 


Cys Thr Phe Ser Ser Gln Val Cys Arg Val Ala Tyr Glu Ile Met Gln 
465                 470                 475                 480 


Thr Leu His Pro Asp Ala Ser Ala Asn Phe His Ser Leu Asp Asp Ile 
                485                 490                 495     


Tyr Tyr Phe Gly Gly Gln Asn Ala His Asn Gln Ile Ala Ile Tyr Ala 
            500                 505                 510         


His Gln Pro Arg Thr Ala Asp Glu Ile Pro Met Glu Pro Gly Asp Ile 
        515                 520                 525             


Ile Gly Val Ala Gly Asn His Trp Asp Gly Tyr Ser Lys Gly Val Asn 
    530                 535                 540                 


Arg Lys Leu Gly Arg Thr Gly Leu Tyr Pro Ser Tyr Lys Val Arg Glu 
545                 550                 555                 560 


Lys Ile Glu Thr Val Lys Tyr Pro Thr Tyr Pro Glu Ala Glu Lys 
                565                 570                 575 


<210>  4109
<211>  305
<212>  PRT
<213>  homo sapiens

<400>  4109

Met Ala Arg Glu Asp Ser Val Lys Cys Leu Arg Cys Leu Leu Tyr Ala 
1               5                   10                  15      


Leu Asn Leu Leu Phe Trp Leu Met Ser Ile Ser Val Leu Ala Val Ser 
            20                  25                  30          


Ala Trp Met Arg Asp Tyr Leu Asn Asn Val Leu Thr Leu Thr Ala Glu 
        35                  40                  45              


Thr Arg Val Glu Glu Ala Val Ile Leu Thr Tyr Phe Pro Val Val His 
    50                  55                  60                  


Pro Val Met Ile Ala Val Cys Cys Phe Leu Ile Ile Val Gly Met Leu 
65                  70                  75                  80  


Gly Tyr Cys Gly Thr Val Lys Arg Asn Leu Leu Leu Leu Ala Trp Tyr 
                85                  90                  95      


Phe Gly Ser Leu Leu Val Ile Phe Cys Val Glu Leu Ala Cys Gly Val 
            100                 105                 110         


Trp Thr Tyr Glu Gln Glu Leu Met Val Pro Val Gln Trp Ser Asp Met 
        115                 120                 125             


Val Thr Leu Lys Ala Arg Met Thr Asn Tyr Gly Leu Pro Arg Tyr Arg 
    130                 135                 140                 


Trp Leu Thr His Ala Trp Asn Phe Phe Gln Arg Glu Phe Lys Cys Cys 
145                 150                 155                 160 


Gly Val Val Tyr Phe Thr Asp Trp Leu Glu Met Thr Glu Met Asp Trp 
                165                 170                 175     


Pro Pro Asp Ser Cys Cys Val Arg Glu Phe Pro Gly Cys Ser Lys Gln 
            180                 185                 190         


Ala His Gln Glu Asp Leu Ser Asp Leu Tyr Gln Glu Gly Cys Gly Lys 
        195                 200                 205             


Lys Met Tyr Ser Phe Leu Arg Gly Thr Lys Gln Leu Gln Val Leu Arg 
    210                 215                 220                 


Phe Leu Gly Ile Ser Ile Gly Val Thr Gln Ile Leu Ala Met Ile Leu 
225                 230                 235                 240 


Thr Ile Thr Leu Leu Trp Ala Leu Tyr Tyr Asp Arg Arg Glu Pro Gly 
                245                 250                 255     


Thr Asp Gln Met Met Ser Leu Lys Asn Asp Asn Ser Gln His Leu Ser 
            260                 265                 270         


Cys Pro Ser Val Glu Leu Leu Lys Pro Ser Leu Ser Arg Ile Phe Glu 
        275                 280                 285             


His Thr Ser Met Ala Asn Ser Phe Asn Thr His Phe Glu Met Glu Glu 
    290                 295                 300                 


Leu 
305 


<210>  4110
<211>  297
<212>  PRT
<213>  homo sapiens

<400>  4110

Met Ala Lys Val Ser Glu Leu Tyr Asp Val Thr Trp Glu Glu Met Arg 
1               5                   10                  15      


Asp Lys Met Arg Lys Trp Arg Glu Glu Asn Ser Arg Asn Ser Glu Gln 
            20                  25                  30          


Ile Val Glu Val Gly Glu Glu Leu Ile Asn Glu Tyr Ala Ser Lys Leu 
        35                  40                  45              


Gly Asp Asp Ile Trp Ile Ile Tyr Glu Gln Val Met Ile Ala Ala Leu 
    50                  55                  60                  


Asp Tyr Gly Arg Asp Asp Leu Ala Leu Phe Cys Leu Gln Glu Leu Arg 
65                  70                  75                  80  


Arg Gln Phe Pro Gly Ser His Arg Val Lys Arg Leu Thr Gly Met Arg 
                85                  90                  95      


Phe Glu Ala Met Glu Arg Tyr Asp Asp Ala Ile Gln Leu Tyr Asp Arg 
            100                 105                 110         


Ile Leu Gln Glu Asp Pro Thr Asn Thr Ala Ala Arg Lys Arg Lys Ile 
        115                 120                 125             


Ala Ile Arg Lys Ala Gln Gly Lys Asn Val Glu Ala Ile Arg Glu Leu 
    130                 135                 140                 


Asn Glu Tyr Leu Glu Gln Phe Val Gly Asp Gln Glu Ala Trp His Glu 
145                 150                 155                 160 


Leu Ala Glu Leu Tyr Ile Asn Glu His Asp Tyr Ala Lys Ala Ala Phe 
                165                 170                 175     


Cys Leu Glu Glu Leu Met Met Thr Asn Pro His Asn His Leu Tyr Cys 
            180                 185                 190         


Gln Gln Tyr Ala Glu Val Lys Tyr Thr Gln Gly Gly Leu Glu Asn Leu 
        195                 200                 205             


Glu Leu Ser Arg Lys Tyr Phe Ala Gln Ala Leu Lys Leu Asn Asn Arg 
    210                 215                 220                 


Asn Met Arg Ala Leu Phe Gly Leu Tyr Met Ser Ala Ser His Ile Ala 
225                 230                 235                 240 


Ser Asn Pro Lys Ala Ser Ala Lys Thr Lys Lys Asp Asn Met Lys Tyr 
                245                 250                 255     


Ala Ser Trp Ala Ala Ser Gln Ile Asn Arg Ala Tyr Gln Phe Ala Gly 
            260                 265                 270         


Arg Ser Lys Lys Glu Thr Lys Tyr Ser Leu Lys Ala Val Glu Asp Met 
        275                 280                 285             


Leu Glu Thr Leu Gln Ile Thr Gln Ser 
    290                 295         


<210>  4111
<211>  857
<212>  PRT
<213>  homo sapiens

<400>  4111

Met Glu Ser Glu Asp Leu Ser Gly Arg Glu Leu Thr Ile Asp Ser Ile 
1               5                   10                  15      


Met Asn Lys Val Arg Asp Ile Lys Asn Lys Phe Lys Asn Glu Asp Leu 
            20                  25                  30          


Thr Asp Glu Leu Ser Leu Asn Lys Ile Ser Ala Asp Thr Thr Asp Asn 
        35                  40                  45              


Ser Gly Thr Val Asn Gln Ile Met Met Met Ala Asn Asn Pro Glu Asp 
    50                  55                  60                  


Trp Leu Ser Leu Leu Leu Lys Leu Glu Lys Asn Ser Val Pro Leu Ser 
65                  70                  75                  80  


Asp Ala Leu Leu Asn Lys Leu Ile Gly Arg Tyr Ser Gln Ala Ile Glu 
                85                  90                  95      


Ala Leu Pro Pro Asp Lys Tyr Gly Gln Asn Glu Ser Phe Ala Arg Ile 
            100                 105                 110         


Gln Val Arg Phe Ala Glu Leu Lys Ala Ile Gln Glu Pro Asp Asp Ala 
        115                 120                 125             


Arg Asp Tyr Phe Gln Met Ala Arg Ala Asn Cys Lys Lys Phe Ala Phe 
    130                 135                 140                 


Val His Ile Ser Phe Ala Gln Phe Glu Leu Ser Gln Gly Asn Val Lys 
145                 150                 155                 160 


Lys Ser Lys Gln Leu Leu Gln Lys Ala Val Glu Arg Gly Ala Val Pro 
                165                 170                 175     


Leu Glu Met Leu Glu Ile Ala Leu Arg Asn Leu Asn Leu Gln Lys Lys 
            180                 185                 190         


Gln Leu Leu Ser Glu Glu Glu Lys Lys Asn Leu Ser Ala Ser Thr Val 
        195                 200                 205             


Leu Thr Ala Gln Glu Ser Phe Ser Gly Ser Leu Gly His Leu Gln Asn 
    210                 215                 220                 


Arg Asn Asn Ser Cys Asp Ser Arg Gly Gln Thr Thr Lys Ala Arg Phe 
225                 230                 235                 240 


Leu Tyr Gly Glu Asn Met Pro Pro Gln Asp Ala Glu Ile Gly Tyr Arg 
                245                 250                 255     


Asn Ser Leu Arg Gln Thr Asn Lys Thr Lys Gln Ser Cys Pro Phe Gly 
            260                 265                 270         


Arg Val Pro Val Asn Leu Leu Asn Ser Pro Asp Cys Asp Val Lys Thr 
        275                 280                 285             


Asp Asp Ser Val Val Pro Cys Phe Met Lys Arg Gln Thr Ser Arg Ser 
    290                 295                 300                 


Glu Cys Arg Asp Leu Val Val Pro Gly Ser Lys Pro Ser Gly Asn Asp 
305                 310                 315                 320 


Ser Cys Glu Leu Arg Asn Leu Lys Ser Val Gln Asn Ser His Phe Lys 
                325                 330                 335     


Glu Pro Leu Val Ser Asp Glu Lys Ser Ser Glu Leu Ile Ile Thr Asp 
            340                 345                 350         


Ser Ile Thr Leu Lys Asn Lys Thr Glu Ser Ser Leu Leu Ala Lys Leu 
        355                 360                 365             


Glu Glu Thr Lys Glu Tyr Gln Glu Pro Glu Val Pro Glu Ser Asn Gln 
    370                 375                 380                 


Lys Gln Trp Gln Ser Lys Arg Lys Ser Glu Cys Ile Asn Gln Asn Pro 
385                 390                 395                 400 


Ala Ala Ser Ser Asn His Trp Gln Ile Pro Glu Leu Ala Arg Lys Val 
                405                 410                 415     


Asn Thr Glu Gln Lys His Thr Thr Phe Glu Gln Pro Val Phe Ser Val 
            420                 425                 430         


Ser Lys Gln Ser Pro Pro Ile Ser Thr Ser Lys Trp Phe Asp Pro Lys 
        435                 440                 445             


Ser Ile Cys Lys Thr Pro Ser Ser Asn Thr Leu Asp Asp Tyr Met Ser 
    450                 455                 460                 


Cys Phe Arg Thr Pro Val Val Lys Asn Asp Phe Pro Pro Ala Cys Gln 
465                 470                 475                 480 


Leu Ser Thr Pro Tyr Gly Gln Pro Ala Cys Phe Gln Gln Gln Gln His 
                485                 490                 495     


Gln Ile Leu Ala Thr Pro Leu Gln Asn Leu Gln Val Leu Ala Ser Ser 
            500                 505                 510         


Ser Ala Asn Glu Cys Ile Ser Val Lys Gly Arg Ile Tyr Ser Ile Leu 
        515                 520                 525             


Lys Gln Ile Gly Ser Gly Gly Ser Ser Lys Val Phe Gln Val Leu Asn 
    530                 535                 540                 


Glu Lys Lys Gln Ile Tyr Ala Ile Lys Tyr Val Asn Leu Glu Glu Ala 
545                 550                 555                 560 


Asp Asn Gln Thr Leu Asp Ser Tyr Arg Asn Glu Ile Ala Tyr Leu Asn 
                565                 570                 575     


Lys Leu Gln Gln His Ser Asp Lys Ile Ile Arg Leu Tyr Asp Tyr Glu 
            580                 585                 590         


Ile Thr Asp Gln Tyr Ile Tyr Met Val Met Glu Cys Gly Asn Ile Asp 
        595                 600                 605             


Leu Asn Ser Trp Leu Lys Lys Lys Lys Ser Ile Asp Pro Trp Glu Arg 
    610                 615                 620                 


Lys Ser Tyr Trp Lys Asn Met Leu Glu Ala Val His Thr Ile His Gln 
625                 630                 635                 640 


His Gly Ile Val His Ser Asp Leu Lys Pro Ala Asn Phe Leu Ile Val 
                645                 650                 655     


Asp Gly Met Leu Lys Leu Ile Asp Phe Gly Ile Ala Asn Gln Met Gln 
            660                 665                 670         


Pro Asp Thr Thr Ser Val Val Lys Asp Ser Gln Val Gly Thr Val Asn 
        675                 680                 685             


Tyr Met Pro Pro Glu Ala Ile Lys Asp Met Ser Ser Ser Arg Glu Asn 
    690                 695                 700                 


Gly Lys Ser Lys Ser Lys Ile Ser Pro Lys Ser Asp Val Trp Ser Leu 
705                 710                 715                 720 


Gly Cys Ile Leu Tyr Tyr Met Thr Tyr Gly Lys Thr Pro Phe Gln Gln 
                725                 730                 735     


Ile Ile Asn Gln Ile Ser Lys Leu His Ala Ile Ile Asp Pro Asn His 
            740                 745                 750         


Glu Ile Glu Phe Pro Asp Ile Pro Glu Lys Asp Leu Gln Asp Val Leu 
        755                 760                 765             


Lys Cys Cys Leu Lys Arg Asp Pro Lys Gln Arg Ile Ser Ile Pro Glu 
    770                 775                 780                 


Leu Leu Ala His Pro Tyr Val Gln Ile Gln Thr His Pro Val Asn Gln 
785                 790                 795                 800 


Met Ala Lys Gly Thr Thr Glu Glu Met Lys Tyr Val Leu Gly Gln Leu 
                805                 810                 815     


Val Gly Leu Asn Ser Pro Asn Ser Ile Leu Lys Ala Ala Lys Thr Leu 
            820                 825                 830         


Tyr Glu His Tyr Ser Gly Gly Glu Ser His Asn Ser Ser Ser Ser Lys 
        835                 840                 845             


Thr Phe Glu Lys Lys Arg Gly Lys Lys 
    850                 855         


<210>  4112
<211>  856
<212>  PRT
<213>  homo sapiens

<400>  4112

Met Glu Ser Glu Asp Leu Ser Gly Arg Glu Leu Thr Ile Asp Ser Ile 
1               5                   10                  15      


Met Asn Lys Val Arg Asp Ile Lys Asn Lys Phe Lys Asn Glu Asp Leu 
            20                  25                  30          


Thr Asp Glu Leu Ser Leu Asn Lys Ile Ser Ala Asp Thr Thr Asp Asn 
        35                  40                  45              


Ser Gly Thr Val Asn Gln Ile Met Met Met Ala Asn Asn Pro Glu Asp 
    50                  55                  60                  


Trp Leu Ser Leu Leu Leu Lys Leu Glu Lys Asn Ser Val Pro Leu Ser 
65                  70                  75                  80  


Asp Ala Leu Leu Asn Lys Leu Ile Gly Arg Tyr Ser Gln Ala Ile Glu 
                85                  90                  95      


Ala Leu Pro Pro Asp Lys Tyr Gly Gln Asn Glu Ser Phe Ala Arg Ile 
            100                 105                 110         


Gln Val Arg Phe Ala Glu Leu Lys Ala Ile Gln Glu Pro Asp Asp Ala 
        115                 120                 125             


Arg Asp Tyr Phe Gln Met Ala Arg Ala Asn Cys Lys Lys Phe Ala Phe 
    130                 135                 140                 


Val His Ile Ser Phe Ala Gln Phe Glu Leu Ser Gln Gly Asn Val Lys 
145                 150                 155                 160 


Lys Ser Lys Gln Leu Leu Gln Lys Ala Val Glu Arg Gly Ala Val Pro 
                165                 170                 175     


Leu Glu Met Leu Glu Ile Ala Leu Arg Asn Leu Asn Leu Gln Lys Lys 
            180                 185                 190         


Gln Leu Leu Ser Glu Glu Glu Lys Lys Asn Leu Ser Ala Ser Thr Val 
        195                 200                 205             


Leu Thr Ala Gln Glu Ser Phe Ser Gly Ser Leu Gly His Leu Gln Asn 
    210                 215                 220                 


Arg Asn Asn Ser Cys Asp Ser Arg Gly Gln Thr Thr Lys Ala Arg Phe 
225                 230                 235                 240 


Leu Tyr Gly Glu Asn Met Pro Pro Gln Asp Ala Glu Ile Gly Tyr Arg 
                245                 250                 255     


Asn Ser Leu Arg Gln Thr Asn Lys Thr Lys Gln Ser Cys Pro Phe Gly 
            260                 265                 270         


Arg Val Pro Val Asn Leu Leu Asn Ser Pro Asp Cys Asp Val Lys Thr 
        275                 280                 285             


Asp Asp Ser Val Val Pro Cys Phe Met Lys Arg Gln Thr Ser Arg Ser 
    290                 295                 300                 


Glu Cys Arg Asp Leu Val Val Pro Gly Ser Lys Pro Ser Gly Asn Asp 
305                 310                 315                 320 


Ser Cys Glu Leu Arg Asn Leu Lys Ser Val Gln Asn Ser His Phe Lys 
                325                 330                 335     


Glu Pro Leu Val Ser Asp Glu Lys Ser Ser Glu Leu Ile Ile Thr Asp 
            340                 345                 350         


Ser Ile Thr Leu Lys Asn Lys Thr Glu Ser Ser Leu Leu Ala Lys Leu 
        355                 360                 365             


Glu Glu Thr Lys Glu Tyr Gln Glu Pro Glu Val Pro Glu Ser Asn Gln 
    370                 375                 380                 


Lys Gln Trp Gln Ser Lys Arg Lys Ser Glu Cys Ile Asn Gln Asn Pro 
385                 390                 395                 400 


Ala Ala Ser Ser Asn His Trp Gln Ile Pro Glu Leu Ala Arg Lys Val 
                405                 410                 415     


Asn Thr Glu Lys His Thr Thr Phe Glu Gln Pro Val Phe Ser Val Ser 
            420                 425                 430         


Lys Gln Ser Pro Pro Ile Ser Thr Ser Lys Trp Phe Asp Pro Lys Ser 
        435                 440                 445             


Ile Cys Lys Thr Pro Ser Ser Asn Thr Leu Asp Asp Tyr Met Ser Cys 
    450                 455                 460                 


Phe Arg Thr Pro Val Val Lys Asn Asp Phe Pro Pro Ala Cys Gln Leu 
465                 470                 475                 480 


Ser Thr Pro Tyr Gly Gln Pro Ala Cys Phe Gln Gln Gln Gln His Gln 
                485                 490                 495     


Ile Leu Ala Thr Pro Leu Gln Asn Leu Gln Val Leu Ala Ser Ser Ser 
            500                 505                 510         


Ala Asn Glu Cys Ile Ser Val Lys Gly Arg Ile Tyr Ser Ile Leu Lys 
        515                 520                 525             


Gln Ile Gly Ser Gly Gly Ser Ser Lys Val Phe Gln Val Leu Asn Glu 
    530                 535                 540                 


Lys Lys Gln Ile Tyr Ala Ile Lys Tyr Val Asn Leu Glu Glu Ala Asp 
545                 550                 555                 560 


Asn Gln Thr Leu Asp Ser Tyr Arg Asn Glu Ile Ala Tyr Leu Asn Lys 
                565                 570                 575     


Leu Gln Gln His Ser Asp Lys Ile Ile Arg Leu Tyr Asp Tyr Glu Ile 
            580                 585                 590         


Thr Asp Gln Tyr Ile Tyr Met Val Met Glu Cys Gly Asn Ile Asp Leu 
        595                 600                 605             


Asn Ser Trp Leu Lys Lys Lys Lys Ser Ile Asp Pro Trp Glu Arg Lys 
    610                 615                 620                 


Ser Tyr Trp Lys Asn Met Leu Glu Ala Val His Thr Ile His Gln His 
625                 630                 635                 640 


Gly Ile Val His Ser Asp Leu Lys Pro Ala Asn Phe Leu Ile Val Asp 
                645                 650                 655     


Gly Met Leu Lys Leu Ile Asp Phe Gly Ile Ala Asn Gln Met Gln Pro 
            660                 665                 670         


Asp Thr Thr Ser Val Val Lys Asp Ser Gln Val Gly Thr Val Asn Tyr 
        675                 680                 685             


Met Pro Pro Glu Ala Ile Lys Asp Met Ser Ser Ser Arg Glu Asn Gly 
    690                 695                 700                 


Lys Ser Lys Ser Lys Ile Ser Pro Lys Ser Asp Val Trp Ser Leu Gly 
705                 710                 715                 720 


Cys Ile Leu Tyr Tyr Met Thr Tyr Gly Lys Thr Pro Phe Gln Gln Ile 
                725                 730                 735     


Ile Asn Gln Ile Ser Lys Leu His Ala Ile Ile Asp Pro Asn His Glu 
            740                 745                 750         


Ile Glu Phe Pro Asp Ile Pro Glu Lys Asp Leu Gln Asp Val Leu Lys 
        755                 760                 765             


Cys Cys Leu Lys Arg Asp Pro Lys Gln Arg Ile Ser Ile Pro Glu Leu 
    770                 775                 780                 


Leu Ala His Pro Tyr Val Gln Ile Gln Thr His Pro Val Asn Gln Met 
785                 790                 795                 800 


Ala Lys Gly Thr Thr Glu Glu Met Lys Tyr Val Leu Gly Gln Leu Val 
                805                 810                 815     


Gly Leu Asn Ser Pro Asn Ser Ile Leu Lys Ala Ala Lys Thr Leu Tyr 
            820                 825                 830         


Glu His Tyr Ser Gly Gly Glu Ser His Asn Ser Ser Ser Ser Lys Thr 
        835                 840                 845             


Phe Glu Lys Lys Arg Gly Lys Lys 
    850                 855     


<210>  4113
<211>  450
<212>  PRT
<213>  homo sapiens

<400>  4113

Met Gly Ala Pro Pro Gly Tyr Arg Pro Ser Ala Trp Val His Leu Leu 
1               5                   10                  15      


His Gln Leu Pro Arg Ala Asp Phe Gln Leu Arg Pro Val Pro Ser Val 
            20                  25                  30          


Phe Ala Pro Gln Glu Gln Glu Tyr Gln Gln Ala Leu Leu Leu Val Ala 
        35                  40                  45              


Ala Leu Ala Gly Leu Gly Leu Gly Leu Ser Leu Ile Phe Ile Ala Val 
    50                  55                  60                  


Tyr Leu Ile Arg Phe Cys Cys Cys Arg Pro Pro Glu Pro Pro Gly Ser 
65                  70                  75                  80  


Lys Ile Pro Ser Pro Gly Gly Gly Cys Val Thr Trp Ser Cys Ile Val 
                85                  90                  95      


Ala Leu Leu Ala Gly Cys Thr Gly Ile Gly Ile Gly Phe Tyr Gly Asn 
            100                 105                 110         


Ser Glu Thr Ser Asp Gly Val Ser Gln Leu Ser Ser Ala Leu Leu His 
        115                 120                 125             


Ala Asn His Thr Leu Ser Thr Ile Asp His Leu Val Leu Glu Thr Val 
    130                 135                 140                 


Glu Arg Leu Gly Glu Ala Val Arg Thr Glu Leu Thr Thr Leu Glu Glu 
145                 150                 155                 160 


Val Leu Glu Pro Arg Thr Glu Leu Val Ala Ala Ala Arg Gly Ala Arg 
                165                 170                 175     


Arg Gln Ala Glu Ala Ala Ala Gln Gln Leu Gln Gly Leu Ala Phe Trp 
            180                 185                 190         


Gln Gly Val Pro Leu Ser Pro Leu Gln Val Ala Glu Asn Val Ser Phe 
        195                 200                 205             


Val Glu Glu Tyr Arg Trp Leu Ala Tyr Val Leu Leu Leu Leu Leu Glu 
    210                 215                 220                 


Leu Leu Val Cys Leu Phe Thr Leu Leu Gly Leu Ala Lys Gln Ser Lys 
225                 230                 235                 240 


Trp Leu Val Ile Val Met Thr Val Met Ser Leu Leu Val Leu Val Leu 
                245                 250                 255     


Ser Trp Gly Ser Met Gly Leu Glu Ala Ala Thr Ala Val Gly Leu Ser 
            260                 265                 270         


Asp Phe Cys Ser Asn Pro Asp Pro Tyr Val Leu Asn Leu Thr Gln Glu 
        275                 280                 285             


Glu Thr Gly Leu Ser Ser Asp Ile Leu Ser Tyr Tyr Leu Leu Cys Asn 
    290                 295                 300                 


Arg Ala Val Ser Asn Pro Phe Gln Gln Arg Leu Thr Leu Ser Gln Arg 
305                 310                 315                 320 


Ala Leu Ala Asn Ile His Ser Gln Leu Leu Gly Leu Glu Arg Glu Ala 
                325                 330                 335     


Val Pro Gln Phe Pro Ser Ala Gln Lys Pro Leu Leu Ser Leu Glu Glu 
            340                 345                 350         


Thr Leu Asn Val Thr Glu Gly Asn Phe His Gln Leu Val Ala Leu Leu 
        355                 360                 365             


His Cys Arg Ser Leu His Lys Asp Tyr Gly Ala Ala Leu Arg Gly Leu 
    370                 375                 380                 


Cys Glu Asp Ala Leu Glu Gly Leu Leu Phe Leu Leu Leu Phe Ser Leu 
385                 390                 395                 400 


Leu Ser Ala Gly Ala Leu Ala Thr Ala Leu Cys Ser Leu Pro Arg Ala 
                405                 410                 415     


Trp Ala Leu Phe Pro Pro Ser Asp Asp Tyr Asp Asp Thr Asp Asp Asp 
            420                 425                 430         


Asp Pro Phe Asn Pro Gln Glu Ser Lys Arg Phe Val Gln Trp Gln Ser 
        435                 440                 445             


Ser Ile 
    450 


<210>  4114
<211>  460
<212>  PRT
<213>  homo sapiens

<400>  4114

Met Gly Ala Pro Pro Gly Tyr Arg Pro Ser Ala Trp Val His Leu Leu 
1               5                   10                  15      


His Gln Leu Pro Arg Ala Asp Phe Gln Leu Arg Pro Val Pro Ser Val 
            20                  25                  30          


Phe Ala Pro Gln Glu Gln Glu Tyr Gln Gln Ala Leu Leu Leu Val Ala 
        35                  40                  45              


Ala Leu Ala Gly Leu Gly Leu Gly Leu Ser Leu Ile Phe Ile Ala Val 
    50                  55                  60                  


Tyr Leu Ile Arg Phe Cys Cys Cys Arg Pro Pro Glu Pro Pro Gly Ser 
65                  70                  75                  80  


Lys Ile Pro Ser Pro Gly Gly Gly Cys Val Thr Trp Ser Cys Ile Val 
                85                  90                  95      


Ala Leu Leu Ala Gly Cys Thr Gly Ile Gly Ile Gly Phe Tyr Gly Asn 
            100                 105                 110         


Ser Glu Thr Ser Asp Gly Val Ser Gln Leu Ser Ser Ala Leu Leu His 
        115                 120                 125             


Ala Asn His Thr Leu Ser Thr Ile Asp His Leu Val Leu Glu Thr Val 
    130                 135                 140                 


Glu Arg Leu Gly Glu Ala Val Arg Thr Glu Leu Thr Thr Leu Glu Glu 
145                 150                 155                 160 


Val Leu Glu Pro Arg Thr Glu Leu Val Ala Ala Ala Arg Gly Ala Arg 
                165                 170                 175     


Arg Gln Ala Glu Ala Ala Ala Gln Gln Leu Gln Gly Leu Ala Phe Trp 
            180                 185                 190         


Gln Gly Val Pro Leu Ser Pro Leu Gln Val Ala Glu Asn Val Ser Phe 
        195                 200                 205             


Val Glu Glu Tyr Arg Trp Leu Ala Tyr Val Leu Leu Leu Leu Leu Glu 
    210                 215                 220                 


Leu Leu Val Cys Leu Phe Thr Leu Leu Gly Leu Ala Lys Gln Ser Lys 
225                 230                 235                 240 


Trp Leu Val Ile Val Met Thr Val Met Ser Leu Leu Val Leu Val Leu 
                245                 250                 255     


Ser Trp Gly Ser Met Gly Leu Glu Ala Ala Thr Ala Val Gly Leu Ser 
            260                 265                 270         


Asp Phe Cys Ser Asn Pro Asp Pro Tyr Val Leu Asn Leu Thr Gln Glu 
        275                 280                 285             


Glu Thr Gly Leu Ser Ser Asp Ile Leu Ser Tyr Tyr Leu Leu Cys Asn 
    290                 295                 300                 


Arg Ala Val Ser Asn Pro Phe Gln Gln Arg Leu Thr Leu Ser Gln Arg 
305                 310                 315                 320 


Ala Leu Ala Asn Ile His Ser Gln Leu Leu Gly Leu Glu Arg Glu Ala 
                325                 330                 335     


Val Pro Gln Phe Pro Ser Ala Gln Lys Pro Leu Leu Ser Leu Glu Glu 
            340                 345                 350         


Thr Leu Asn Val Thr Glu Gly Asn Phe His Gln Leu Val Ala Leu Leu 
        355                 360                 365             


His Cys Arg Ser Leu His Lys Asp Tyr Gly Ala Ala Leu Arg Gly Leu 
    370                 375                 380                 


Cys Glu Asp Ala Leu Glu Gly Leu Leu Phe Leu Leu Leu Phe Ser Leu 
385                 390                 395                 400 


Leu Ser Ala Gly Ala Leu Ala Thr Ala Leu Cys Ser Leu Pro Arg Ala 
                405                 410                 415     


Trp Ala Leu Phe Pro Pro Arg Asn Pro Ser Ala Leu Cys Ser Gly Ser 
            420                 425                 430         


Arg Leu Ser Glu Pro Leu Leu Pro Ala Gly Leu Glu Pro Gly Ser Pro 
        435                 440                 445             


Leu Arg Ser Phe Pro Gly Cys Arg Arg Arg Pro His 
    450                 455                 460 


<210>  4115
<211>  449
<212>  PRT
<213>  homo sapiens

<400>  4115

Met Arg Glu Cys Ile Ser Ile His Val Gly Gln Ala Gly Val Gln Ile 
1               5                   10                  15      


Gly Asn Ala Cys Trp Glu Leu Tyr Cys Leu Glu His Gly Ile Gln Pro 
            20                  25                  30          


Asp Gly Gln Met Pro Ser Asp Lys Thr Ile Gly Gly Gly Asp Asp Ser 
        35                  40                  45              


Phe Asn Thr Phe Phe Ser Glu Thr Gly Ala Gly Lys His Val Pro Arg 
    50                  55                  60                  


Ala Val Phe Val Asp Leu Glu Pro Thr Val Ile Asp Glu Val Arg Thr 
65                  70                  75                  80  


Gly Thr Tyr Arg Gln Leu Phe His Pro Glu Gln Leu Ile Thr Gly Lys 
                85                  90                  95      


Glu Asp Ala Ala Asn Asn Tyr Ala Arg Gly His Tyr Thr Ile Gly Lys 
            100                 105                 110         


Glu Ile Ile Asp Leu Val Leu Asp Arg Ile Arg Lys Leu Ala Asp Gln 
        115                 120                 125             


Cys Thr Gly Leu Gln Gly Phe Leu Val Phe His Ser Phe Gly Gly Gly 
    130                 135                 140                 


Thr Gly Ser Gly Phe Thr Ser Leu Leu Met Glu Arg Leu Ser Val Asp 
145                 150                 155                 160 


Tyr Gly Lys Lys Ser Lys Leu Glu Phe Ser Ile Tyr Pro Ala Pro Gln 
                165                 170                 175     


Val Ser Thr Ala Val Val Glu Pro Tyr Asn Ser Ile Leu Thr Thr His 
            180                 185                 190         


Thr Thr Leu Glu His Ser Asp Cys Ala Phe Met Val Asp Asn Glu Ala 
        195                 200                 205             


Ile Tyr Asp Ile Cys Arg Arg Asn Leu Asp Ile Glu Arg Pro Thr Tyr 
    210                 215                 220                 


Thr Asn Leu Asn Arg Leu Ile Ser Gln Ile Val Ser Ser Ile Thr Ala 
225                 230                 235                 240 


Ser Leu Arg Phe Asp Gly Ala Leu Asn Val Asp Leu Thr Glu Phe Gln 
                245                 250                 255     


Thr Asn Leu Val Pro Tyr Pro Arg Ile His Phe Pro Leu Ala Thr Tyr 
            260                 265                 270         


Ala Pro Val Ile Ser Ala Glu Lys Ala Tyr His Glu Gln Leu Thr Val 
        275                 280                 285             


Ala Glu Ile Thr Asn Ala Cys Phe Glu Pro Ala Asn Gln Met Val Lys 
    290                 295                 300                 


Cys Asp Pro Arg His Gly Lys Tyr Met Ala Cys Cys Leu Leu Tyr Arg 
305                 310                 315                 320 


Gly Asp Val Val Pro Lys Asp Val Asn Ala Ala Ile Ala Thr Ile Lys 
                325                 330                 335     


Thr Lys Arg Thr Ile Gln Phe Val Asp Trp Cys Pro Thr Gly Phe Lys 
            340                 345                 350         


Val Gly Ile Asn Tyr Gln Pro Pro Thr Val Val Pro Gly Gly Asp Leu 
        355                 360                 365             


Ala Lys Val Gln Arg Ala Val Cys Met Leu Ser Asn Thr Thr Ala Val 
    370                 375                 380                 


Ala Glu Ala Trp Ala Arg Leu Asp His Lys Phe Asp Leu Met Tyr Ala 
385                 390                 395                 400 


Lys Arg Ala Phe Val His Trp Tyr Val Gly Glu Gly Met Glu Glu Gly 
                405                 410                 415     


Glu Phe Ser Glu Ala Arg Glu Asp Met Ala Ala Leu Glu Lys Asp Tyr 
            420                 425                 430         


Glu Glu Val Gly Ala Asp Ser Ala Asp Gly Glu Asp Glu Gly Glu Glu 
        435                 440                 445             


Tyr 
    


<210>  4116
<211>  382
<212>  PRT
<213>  homo sapiens

<400>  4116

Met Ser Val Leu Arg Arg Met Met Arg Val Ser Asn Arg Ser Leu Leu 
1               5                   10                  15      


Ala Phe Ile Phe Phe Phe Ser Leu Ser Ser Ser Cys Leu Tyr Phe Ile 
            20                  25                  30          


Tyr Val Ala Pro Gly Ile Ala Asn Thr Tyr Leu Phe Met Val Gln Ala 
        35                  40                  45              


Arg Gly Ile Met Leu Arg Glu Asn Val Lys Thr Ile Gly His Met Ile 
    50                  55                  60                  


Arg Leu Tyr Thr Asn Lys Asn Ser Thr Leu Asn Gly Thr Asp Tyr Pro 
65                  70                  75                  80  


Glu Gly Asn Asn Ser Ser Asp Tyr Leu Val Gln Thr Thr Thr Tyr Leu 
                85                  90                  95      


Pro Glu Asn Phe Thr Tyr Ser Pro Tyr Leu Pro Cys Pro Glu Lys Leu 
            100                 105                 110         


Pro Tyr Met Arg Gly Phe Leu Asn Val Asn Val Ser Glu Val Ser Phe 
        115                 120                 125             


Asp Glu Ile His Gln Leu Phe Ser Lys Asp Leu Asp Ile Glu Pro Gly 
    130                 135                 140                 


Gly His Trp Arg Pro Lys Asp Cys Lys Pro Arg Trp Lys Val Ala Val 
145                 150                 155                 160 


Leu Ile Pro Phe Arg Asn Arg His Glu His Leu Pro Ile Phe Phe Leu 
                165                 170                 175     


His Leu Ile Pro Met Leu Gln Lys Gln Arg Leu Glu Phe Ala Phe Tyr 
            180                 185                 190         


Val Ile Glu Gln Thr Gly Thr Gln Pro Phe Asn Arg Ala Met Leu Phe 
        195                 200                 205             


Asn Val Gly Phe Lys Glu Ala Met Lys Asp Ser Val Trp Asp Cys Val 
    210                 215                 220                 


Ile Phe His Asp Val Asp His Leu Pro Glu Asn Asp Arg Asn Tyr Tyr 
225                 230                 235                 240 


Gly Cys Gly Glu Met Pro Arg His Phe Ala Ala Lys Leu Asp Lys Tyr 
                245                 250                 255     


Met Tyr Ile Leu Pro Tyr Lys Glu Phe Phe Gly Gly Val Ser Gly Leu 
            260                 265                 270         


Thr Val Glu Gln Phe Arg Lys Ile Asn Gly Phe Pro Asn Ala Phe Trp 
        275                 280                 285             


Gly Trp Gly Gly Glu Asp Asp Asp Leu Trp Asn Arg Val His Tyr Ala 
    290                 295                 300                 


Gly Tyr Asn Val Thr Arg Pro Glu Gly Asp Leu Gly Lys Tyr Lys Ser 
305                 310                 315                 320 


Ile Pro His His His Arg Gly Glu Val Gln Phe Leu Gly Arg Tyr Lys 
                325                 330                 335     


Leu Leu Arg Tyr Ser Lys Glu Arg Gln Tyr Ile Asp Gly Leu Asn Asn 
            340                 345                 350         


Leu Ile Tyr Arg Pro Lys Ile Leu Val Asp Arg Leu Tyr Thr Asn Ile 
        355                 360                 365             


Ser Val Asn Leu Met Pro Glu Leu Ala Pro Ile Glu Asp Tyr 
    370                 375                 380         


<210>  4117
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  4117

Met Glu Glu Gln Pro Gln Met Gln Asp Ala Asp Glu Pro Ala Asp Ser 
1               5                   10                  15      


Gly Gly Glu Gly Arg Ala Gly Gly Pro Pro Gln Val Ala Gly Ala Gln 
            20                  25                  30          


Ala Ala Cys Ser Glu Asp Arg Met Thr Leu Leu Leu Arg Leu Arg Ala 
        35                  40                  45              


Gln Thr Lys Gln Gln Leu Leu Glu Tyr Lys Ser Met Val Asp Ala Ser 
    50                  55                  60                  


Glu Glu Lys Thr Pro Glu Gln Ile Met Gln Glu Lys Gln Ile Glu Ala 
65                  70                  75                  80  


Lys Ile Glu Asp Leu Glu Asn Glu Ile Glu Glu Val Lys Val Ala Phe 
                85                  90                  95      


Glu Ile Lys Lys Leu Ala Leu Asp Arg Met Arg Leu Ser Thr Ala Leu 
            100                 105                 110         


Lys Lys Asn Leu Glu Lys Ile Ser Arg Gln Ser Ser Val Leu Met Asp 
        115                 120                 125             


Asn Met Lys His Leu Leu Glu Leu Asn Lys Leu Ile Met Lys Ser Gln 
    130                 135                 140                 


Gln Glu Ser Trp Asp Leu Glu Glu Lys Leu Leu Asp Ile Arg Lys Lys 
145                 150                 155                 160 


Arg Leu Gln Leu Lys Gln Ala Ser Glu Ser Lys Leu Leu Glu Ile Gln 
                165                 170                 175     


Thr Glu Lys Asn Lys Gln Lys Ile Asp Leu Asp Ser Met Glu Asn Ser 
            180                 185                 190         


Glu Arg Ile Lys Ile Ile Arg Gln Asn Leu Gln Met Glu Ile Lys Ile 
        195                 200                 205             


Thr Thr Val Ile Gln His Val Phe Gln Asn Leu Ile Leu Gly Ser Lys 
    210                 215                 220                 


Val Asn Trp Ala Glu Asp Pro Ala Leu Lys Glu Ile Val Leu Gln Leu 
225                 230                 235                 240 


Glu Lys Asn Val Asp Met Met 
                245         


<210>  4118
<211>  132
<212>  PRT
<213>  homo sapiens

<400>  4118

Met Ser Asn Lys Phe Leu Gly Thr Trp Lys Leu Val Ser Ser Glu Asn 
1               5                   10                  15      


Phe Asp Asp Tyr Met Lys Ala Leu Gly Val Gly Leu Ala Thr Arg Lys 
            20                  25                  30          


Leu Gly Asn Leu Ala Lys Pro Thr Val Ile Ile Ser Lys Lys Gly Asp 
        35                  40                  45              


Ile Ile Thr Ile Arg Thr Glu Ser Thr Phe Lys Asn Thr Glu Ile Ser 
    50                  55                  60                  


Phe Lys Leu Gly Gln Glu Phe Glu Glu Thr Thr Ala Asp Asn Arg Lys 
65                  70                  75                  80  


Thr Lys Ser Ile Val Thr Leu Gln Arg Gly Ser Leu Asn Gln Val Gln 
                85                  90                  95      


Arg Trp Asp Gly Lys Glu Thr Thr Ile Lys Arg Lys Leu Val Asn Gly 
            100                 105                 110         


Lys Met Val Ala Glu Cys Lys Met Lys Gly Val Val Cys Thr Arg Ile 
        115                 120                 125             


Tyr Glu Lys Val 
    130         


<210>  4119
<211>  720
<212>  PRT
<213>  homo sapiens

<400>  4119

Met Thr Thr Glu Lys Ser Leu Val Thr Glu Ala Glu Asn Ser Gln His 
1               5                   10                  15      


Gln Gln Lys Glu Glu Gly Glu Glu Ala Ile Asn Ser Gly Gln Gln Glu 
            20                  25                  30          


Pro Gln Gln Glu Glu Ser Cys Gln Thr Ala Ala Glu Gly Asp Asn Trp 
        35                  40                  45              


Cys Glu Gln Lys Leu Lys Ala Ser Asn Gly Asp Thr Pro Thr His Glu 
    50                  55                  60                  


Asp Leu Thr Lys Asn Lys Glu Arg Thr Ser Glu Ser Arg Gly Leu Ser 
65                  70                  75                  80  


Arg Leu Phe Ser Ser Phe Leu Lys Arg Pro Lys Ser Gln Val Ser Glu 
                85                  90                  95      


Glu Glu Gly Lys Glu Val Glu Ser Asp Lys Glu Lys Gly Glu Gly Gly 
            100                 105                 110         


Gln Lys Glu Ile Glu Phe Gly Thr Ser Leu Asp Glu Glu Ile Ile Leu 
        115                 120                 125             


Lys Ala Pro Ile Ala Ala Pro Glu Pro Glu Leu Lys Thr Asp Pro Ser 
    130                 135                 140                 


Leu Asp Leu His Ser Leu Ser Ser Ala Glu Thr Gln Pro Ala Gln Glu 
145                 150                 155                 160 


Glu Leu Arg Glu Asp Pro Asp Phe Glu Ile Lys Glu Gly Glu Gly Leu 
                165                 170                 175     


Glu Glu Cys Ser Lys Ile Glu Val Lys Glu Glu Ser Pro Gln Ser Lys 
            180                 185                 190         


Ala Glu Thr Glu Leu Lys Ala Ser Gln Lys Pro Ile Arg Lys His Arg 
        195                 200                 205             


Asn Met His Cys Lys Val Ser Leu Leu Asp Asp Thr Val Tyr Glu Cys 
    210                 215                 220                 


Val Val Glu Lys His Ala Lys Gly Gln Asp Leu Leu Lys Arg Val Cys 
225                 230                 235                 240 


Glu His Leu Asn Leu Leu Glu Glu Asp Tyr Phe Gly Leu Ala Ile Trp 
                245                 250                 255     


Asp Asn Ala Thr Ser Lys Thr Trp Leu Asp Ser Ala Lys Glu Ile Lys 
            260                 265                 270         


Lys Gln Val Arg Gly Val Pro Trp Asn Phe Thr Phe Asn Val Lys Phe 
        275                 280                 285             


Tyr Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr 
    290                 295                 300                 


Leu Cys Leu Gln Leu Arg Gln Asp Ile Val Ala Gly Arg Leu Pro Cys 
305                 310                 315                 320 


Ser Phe Ala Thr Leu Ala Leu Leu Gly Ser Tyr Thr Ile Gln Ser Glu 
                325                 330                 335     


Leu Gly Asp Tyr Asp Pro Glu Leu His Gly Val Asp Tyr Val Ser Asp 
            340                 345                 350         


Phe Lys Leu Ala Pro Asn Gln Thr Lys Glu Leu Glu Glu Lys Val Met 
        355                 360                 365             


Glu Leu His Lys Ser Tyr Arg Ser Met Thr Pro Ala Gln Ala Asp Leu 
    370                 375                 380                 


Glu Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu 
385                 390                 395                 400 


His Lys Ala Lys Asp Leu Glu Gly Val Asp Ile Ile Leu Gly Val Cys 
                405                 410                 415     


Ser Ser Gly Leu Leu Val Tyr Lys Asp Lys Leu Arg Ile Asn Arg Phe 
            420                 425                 430         


Pro Trp Pro Lys Val Leu Lys Ile Ser Tyr Lys Arg Ser Ser Phe Phe 
        435                 440                 445             


Ile Lys Ile Arg Pro Gly Glu Gln Glu Gln Tyr Glu Ser Thr Ile Gly 
    450                 455                 460                 


Phe Lys Leu Pro Ser Tyr Arg Ala Ala Lys Lys Leu Trp Lys Val Cys 
465                 470                 475                 480 


Val Glu His His Thr Phe Phe Arg Leu Thr Ser Thr Asp Thr Ile Pro 
                485                 490                 495     


Lys Ser Lys Phe Leu Ala Leu Gly Ser Lys Phe Arg Tyr Ser Gly Arg 
            500                 505                 510         


Thr Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala 
        515                 520                 525             


Pro His Phe Glu Arg Thr Ala Ser Lys Arg Ala Ser Arg Ser Leu Asp 
    530                 535                 540                 


Gly Ala Ala Ala Val Asp Ser Ala Asp Arg Ser Pro Arg Pro Thr Ser 
545                 550                 555                 560 


Ala Pro Ala Ile Thr Gln Gly Gln Val Ala Glu Gly Gly Val Leu Asp 
                565                 570                 575     


Ala Ser Ala Lys Lys Thr Val Val Pro Lys Ala Gln Lys Glu Thr Val 
            580                 585                 590         


Lys Ala Glu Val Lys Lys Glu Asp Glu Pro Pro Glu Gln Ala Glu Pro 
        595                 600                 605             


Glu Pro Thr Glu Ala Trp Lys Val Glu Lys Thr His Ile Glu Val Thr 
    610                 615                 620                 


Val Pro Thr Ser Asn Gly Asp Gln Thr Gln Lys Lys Arg Glu Arg Leu 
625                 630                 635                 640 


Asp Gly Glu Asn Ile Tyr Ile Arg His Ser Asn Leu Met Leu Glu Asp 
                645                 650                 655     


Leu Asp Lys Ser Gln Glu Glu Ile Lys Lys His His Ala Ser Ile Ser 
            660                 665                 670         


Glu Leu Lys Lys Asn Phe Met Glu Ser Val Pro Glu Pro Arg Pro Ser 
        675                 680                 685             


Glu Trp Asp Lys Arg Leu Ser Thr His Ser Pro Phe Arg Thr Leu Asn 
    690                 695                 700                 


Ile Asn Gly Gln Ile Pro Thr Gly Glu Gly Val Ser Thr Leu Ser Thr 
705                 710                 715                 720 


<210>  4120
<211>  254
<212>  PRT
<213>  homo sapiens

<400>  4120

Met Ser Ala Gly Gly Asp Phe Gly Asn Pro Leu Arg Lys Phe Lys Leu 
1               5                   10                  15      


Val Phe Leu Gly Glu Gln Ser Val Ala Lys Thr Ser Leu Ile Thr Arg 
            20                  25                  30          


Phe Arg Tyr Asp Ser Phe Asp Asn Thr Tyr Gln Ala Ile Ile Gly Ile 
        35                  40                  45              


Asp Phe Leu Ser Lys Thr Met Tyr Leu Glu Asp Gly Thr Ile Gly Leu 
    50                  55                  60                  


Arg Leu Trp Asp Thr Ala Gly Gln Glu Arg Leu Arg Ser Leu Ile Pro 
65                  70                  75                  80  


Arg Tyr Ile Arg Asp Ser Ala Ala Ala Val Val Val Tyr Asp Ile Thr 
                85                  90                  95      


Asn Val Asn Ser Phe Gln Gln Thr Thr Lys Trp Ile Asp Asp Val Arg 
            100                 105                 110         


Thr Glu Arg Gly Ser Asp Val Ile Ile Thr Leu Val Gly Asn Arg Thr 
        115                 120                 125             


Asp Leu Ala Asp Lys Arg Gln Val Ser Val Glu Glu Gly Glu Arg Lys 
    130                 135                 140                 


Ala Lys Gly Leu Asn Val Thr Phe Ile Glu Thr Arg Ala Lys Ala Gly 
145                 150                 155                 160 


Tyr Asn Val Lys Gln Leu Phe Arg Arg Val Ala Ala Ala Leu Pro Gly 
                165                 170                 175     


Met Glu Ser Thr Gln Asp Gly Ser Arg Glu Asp Met Ser Asp Ile Lys 
            180                 185                 190         


Leu Glu Lys Pro Gln Glu Gln Thr Val Ser Glu Gly Gly Cys Ser Cys 
        195                 200                 205             


Tyr Ser Pro Met Ser Ser Ser Thr Leu Pro Gln Lys Pro Pro Tyr Ser 
    210                 215                 220                 


Phe Ile Asp Cys Ser Val Asn Ile Gly Leu Asn Leu Phe Pro Ser Leu 
225                 230                 235                 240 


Ile Thr Phe Cys Asn Ser Ser Leu Leu Pro Val Ser Trp Arg 
                245                 250                 


<210>  4121
<211>  254
<212>  PRT
<213>  homo sapiens

<400>  4121

Met Ser Ala Gly Gly Asp Phe Gly Asn Pro Leu Arg Lys Phe Lys Leu 
1               5                   10                  15      


Val Phe Leu Gly Glu Gln Ser Val Ala Lys Thr Ser Leu Ile Thr Arg 
            20                  25                  30          


Phe Arg Tyr Asp Ser Phe Asp Asn Thr Tyr Gln Ala Ile Ile Gly Ile 
        35                  40                  45              


Asp Phe Leu Ser Lys Thr Met Tyr Leu Glu Asp Gly Thr Ile Gly Leu 
    50                  55                  60                  


Arg Leu Trp Asp Thr Ala Gly Gln Glu Arg Leu Arg Ser Leu Ile Pro 
65                  70                  75                  80  


Arg Tyr Ile Arg Asp Ser Ala Ala Ala Val Val Val Tyr Asp Ile Thr 
                85                  90                  95      


Asn Val Asn Ser Phe Gln Gln Thr Thr Lys Trp Ile Asp Asp Val Arg 
            100                 105                 110         


Thr Glu Gly Gly Ser Asp Val Ile Ile Thr Leu Val Gly Asn Lys Thr 
        115                 120                 125             


Asp Leu Ala Asp Lys Arg Gln Val Ser Ile Glu Glu Gly Glu Arg Lys 
    130                 135                 140                 


Ala Lys Gly Leu Asn Val Thr Phe Ile Glu Thr Arg Ala Lys Ala Gly 
145                 150                 155                 160 


Tyr Asn Val Lys Gln Leu Phe Arg Arg Val Ala Ala Ala Leu Pro Gly 
                165                 170                 175     


Met Glu Ser Thr Gln Asp Gly Ser Arg Glu Asp Met Ser Asp Ile Lys 
            180                 185                 190         


Leu Glu Lys Pro Gln Glu Gln Thr Val Ser Glu Gly Gly Cys Ser Cys 
        195                 200                 205             


Tyr Ser Pro Met Ser Ser Ser Thr Leu Pro Gln Lys Pro Pro Tyr Ser 
    210                 215                 220                 


Phe Ile Asp Cys Ser Val Asn Ile Gly Leu Asn Leu Phe Pro Ser Leu 
225                 230                 235                 240 


Ile Thr Phe Cys Asn Ser Ser Leu Leu Pro Val Ser Trp Arg 
                245                 250                 


<210>  4122
<211>  4128
<212>  PRT
<213>  homo sapiens

<400>  4122

Met Ala Gly Ser Gly Ala Gly Val Arg Cys Ser Leu Leu Arg Leu Gln 
1               5                   10                  15      


Glu Thr Leu Ser Ala Ala Asp Arg Cys Gly Ala Ala Leu Ala Gly His 
            20                  25                  30          


Gln Leu Ile Arg Gly Leu Gly Gln Glu Cys Val Leu Ser Ser Ser Pro 
        35                  40                  45              


Ala Val Leu Ala Leu Gln Thr Ser Leu Val Phe Ser Arg Asp Phe Gly 
    50                  55                  60                  


Leu Leu Val Phe Val Arg Lys Ser Leu Asn Ser Ile Glu Phe Arg Glu 
65                  70                  75                  80  


Cys Arg Glu Glu Ile Leu Lys Phe Leu Cys Ile Phe Leu Glu Lys Met 
                85                  90                  95      


Gly Gln Lys Ile Ala Pro Tyr Ser Val Glu Ile Lys Asn Thr Cys Thr 
            100                 105                 110         


Ser Val Tyr Thr Lys Asp Arg Ala Ala Lys Cys Lys Ile Pro Ala Leu 
        115                 120                 125             


Asp Leu Leu Ile Lys Leu Leu Gln Thr Phe Arg Ser Ser Arg Leu Met 
    130                 135                 140                 


Asp Glu Phe Lys Ile Gly Glu Leu Phe Ser Lys Phe Tyr Gly Glu Leu 
145                 150                 155                 160 


Ala Leu Lys Lys Lys Ile Pro Asp Thr Val Leu Glu Lys Val Tyr Glu 
                165                 170                 175     


Leu Leu Gly Leu Leu Gly Glu Val His Pro Ser Glu Met Ile Asn Asn 
            180                 185                 190         


Ala Glu Asn Leu Phe Arg Ala Phe Leu Gly Glu Leu Lys Thr Gln Met 
        195                 200                 205             


Thr Ser Ala Val Arg Glu Pro Lys Leu Pro Val Leu Ala Gly Cys Leu 
    210                 215                 220                 


Lys Gly Leu Ser Ser Leu Leu Cys Asn Phe Thr Lys Ser Met Glu Glu 
225                 230                 235                 240 


Asp Pro Gln Thr Ser Arg Glu Ile Phe Asn Phe Val Leu Lys Ala Ile 
                245                 250                 255     


Arg Pro Gln Ile Asp Leu Lys Arg Tyr Ala Val Pro Ser Ala Gly Leu 
            260                 265                 270         


Arg Leu Phe Ala Leu His Ala Ser Gln Phe Ser Thr Cys Leu Leu Asp 
        275                 280                 285             


Asn Tyr Val Ser Leu Phe Glu Val Leu Leu Lys Trp Cys Ala His Thr 
    290                 295                 300                 


Asn Val Glu Leu Lys Lys Ala Ala Leu Ser Ala Leu Glu Ser Phe Leu 
305                 310                 315                 320 


Lys Gln Val Ser Asn Met Val Ala Lys Asn Ala Glu Met His Lys Asn 
                325                 330                 335     


Lys Leu Gln Tyr Phe Met Glu Gln Phe Tyr Gly Ile Ile Arg Asn Val 
            340                 345                 350         


Asp Ser Asn Asn Lys Glu Leu Ser Ile Ala Ile Arg Gly Tyr Gly Leu 
        355                 360                 365             


Phe Ala Gly Pro Cys Lys Val Ile Asn Ala Lys Asp Val Asp Phe Met 
    370                 375                 380                 


Tyr Val Glu Leu Ile Gln Arg Cys Lys Gln Met Phe Leu Thr Gln Thr 
385                 390                 395                 400 


Asp Thr Gly Asp Asp Arg Val Tyr Gln Met Pro Ser Phe Leu Gln Ser 
                405                 410                 415     


Val Ala Ser Val Leu Leu Tyr Leu Asp Thr Val Pro Glu Val Tyr Thr 
            420                 425                 430         


Pro Val Leu Glu His Leu Val Val Met Gln Ile Asp Ser Phe Pro Gln 
        435                 440                 445             


Tyr Ser Pro Lys Met Gln Leu Val Cys Cys Arg Ala Ile Val Lys Val 
    450                 455                 460                 


Phe Leu Ala Leu Ala Ala Lys Gly Pro Val Leu Arg Asn Cys Ile Ser 
465                 470                 475                 480 


Thr Val Val His Gln Gly Leu Ile Arg Ile Cys Ser Lys Pro Val Val 
                485                 490                 495     


Leu Pro Lys Gly Pro Glu Ser Glu Ser Glu Asp His Arg Ala Ser Gly 
            500                 505                 510         


Glu Val Arg Thr Gly Lys Trp Lys Val Pro Thr Tyr Lys Asp Tyr Val 
        515                 520                 525             


Asp Leu Phe Arg His Leu Leu Ser Ser Asp Gln Met Met Asp Ser Ile 
    530                 535                 540                 


Leu Ala Asp Glu Ala Phe Phe Ser Val Asn Ser Ser Ser Glu Ser Leu 
545                 550                 555                 560 


Asn His Leu Leu Tyr Asp Glu Phe Val Lys Ser Val Leu Lys Ile Val 
                565                 570                 575     


Glu Lys Leu Asp Leu Thr Leu Glu Ile Gln Thr Val Gly Glu Gln Glu 
            580                 585                 590         


Asn Gly Asp Glu Ala Pro Gly Val Trp Met Ile Pro Thr Ser Asp Pro 
        595                 600                 605             


Ala Ala Asn Leu His Pro Ala Lys Pro Lys Asp Phe Ser Ala Phe Ile 
    610                 615                 620                 


Asn Leu Val Glu Phe Cys Arg Glu Ile Leu Pro Glu Lys Gln Ala Glu 
625                 630                 635                 640 


Phe Phe Glu Pro Trp Val Tyr Ser Phe Ser Tyr Glu Leu Ile Leu Gln 
                645                 650                 655     


Ser Thr Arg Leu Pro Leu Ile Ser Gly Phe Tyr Lys Leu Leu Ser Ile 
            660                 665                 670         


Thr Val Arg Asn Ala Lys Lys Ile Lys Tyr Phe Glu Gly Val Ser Pro 
        675                 680                 685             


Lys Ser Leu Lys His Ser Pro Glu Asp Pro Glu Lys Tyr Ser Cys Phe 
    690                 695                 700                 


Ala Leu Phe Val Lys Phe Gly Lys Glu Val Ala Val Lys Met Lys Gln 
705                 710                 715                 720 


Tyr Lys Asp Glu Leu Leu Ala Ser Cys Leu Thr Phe Leu Leu Ser Leu 
                725                 730                 735     


Pro His Asn Ile Ile Glu Leu Asp Val Arg Ala Tyr Val Pro Ala Leu 
            740                 745                 750         


Gln Met Ala Phe Lys Leu Gly Leu Ser Tyr Thr Pro Leu Ala Glu Val 
        755                 760                 765             


Gly Leu Asn Ala Leu Glu Glu Trp Ser Ile Tyr Ile Asp Arg His Val 
    770                 775                 780                 


Met Gln Pro Tyr Tyr Lys Asp Ile Leu Pro Cys Leu Asp Gly Tyr Leu 
785                 790                 795                 800 


Lys Thr Ser Ala Leu Ser Asp Glu Thr Lys Asn Asn Trp Glu Val Ser 
                805                 810                 815     


Ala Leu Ser Arg Ala Ala Gln Lys Gly Phe Asn Lys Val Val Leu Lys 
            820                 825                 830         


His Leu Lys Lys Thr Lys Asn Leu Ser Ser Asn Glu Ala Ile Ser Leu 
        835                 840                 845             


Glu Glu Ile Arg Ile Arg Val Val Gln Met Leu Gly Ser Leu Gly Gly 
    850                 855                 860                 


Gln Ile Asn Lys Asn Leu Leu Thr Val Thr Ser Ser Asp Glu Met Met 
865                 870                 875                 880 


Lys Ser Tyr Val Ala Trp Asp Arg Glu Lys Arg Leu Ser Phe Ala Val 
                885                 890                 895     


Pro Phe Arg Glu Met Lys Pro Val Ile Phe Leu Asp Val Phe Leu Pro 
            900                 905                 910         


Arg Val Thr Glu Leu Ala Leu Thr Ala Ser Asp Arg Gln Thr Lys Val 
        915                 920                 925             


Ala Ala Cys Glu Leu Leu His Ser Met Val Met Phe Met Leu Gly Lys 
    930                 935                 940                 


Ala Thr Gln Met Pro Glu Gly Gly Gln Gly Ala Pro Pro Met Tyr Gln 
945                 950                 955                 960 


Leu Tyr Lys Arg Thr Phe Pro Val Leu Leu Arg Leu Ala Cys Asp Val 
                965                 970                 975     


Asp Gln Val Thr Arg Gln Leu Tyr Glu Pro Leu Val Met Gln Leu Ile 
            980                 985                 990         


His Trp Phe Thr Asn Asn Lys Lys  Phe Glu Ser Gln Asp  Thr Val Ala 
        995                 1000                 1005             


Leu Leu  Glu Ala Ile Leu Asp  Gly Ile Val Asp Pro  Val Asp Ser 
    1010                 1015                 1020             


Thr Leu  Arg Asp Phe Cys Gly  Arg Cys Ile Arg Glu  Phe Leu Lys 
    1025                 1030                 1035             


Trp Ser  Ile Lys Gln Ile Thr  Pro Gln Gln Gln Glu  Lys Ser Pro 
    1040                 1045                 1050             


Val Asn  Thr Lys Ser Leu Phe  Lys Arg Leu Tyr Ser  Leu Ala Leu 
    1055                 1060                 1065             


His Pro  Asn Ala Phe Lys Arg  Leu Gly Ala Ser Leu  Ala Phe Asn 
    1070                 1075                 1080             


Asn Ile  Tyr Arg Glu Phe Arg  Glu Glu Glu Ser Leu  Val Glu Gln 
    1085                 1090                 1095             


Phe Val  Phe Glu Ala Leu Val  Ile Tyr Met Glu Ser  Leu Ala Leu 
    1100                 1105                 1110             


Ala His  Ala Asp Glu Lys Ser  Leu Gly Thr Ile Gln  Gln Cys Cys 
    1115                 1120                 1125             


Asp Ala  Ile Asp His Leu Cys  Arg Ile Ile Glu Lys  Lys His Val 
    1130                 1135                 1140             


Ser Leu  Asn Lys Ala Lys Lys  Arg Arg Leu Pro Arg  Gly Phe Pro 
    1145                 1150                 1155             


Pro Ser  Ala Ser Leu Cys Leu  Leu Asp Leu Val Lys  Trp Leu Leu 
    1160                 1165                 1170             


Ala His  Cys Gly Arg Pro Gln  Thr Glu Cys Arg His  Lys Ser Ile 
    1175                 1180                 1185             


Glu Leu  Phe Tyr Lys Phe Val  Pro Leu Leu Pro Gly  Asn Arg Ser 
    1190                 1195                 1200             


Pro Asn  Leu Trp Leu Lys Asp  Val Leu Lys Glu Glu  Gly Val Ser 
    1205                 1210                 1215             


Phe Leu  Ile Asn Thr Phe Glu  Gly Gly Gly Cys Gly  Gln Pro Ser 
    1220                 1225                 1230             


Gly Ile  Leu Ala Gln Pro Thr  Leu Leu Tyr Leu Arg  Gly Pro Phe 
    1235                 1240                 1245             


Ser Leu  Gln Ala Thr Leu Cys  Trp Leu Asp Leu Leu  Leu Ala Ala 
    1250                 1255                 1260             


Leu Glu  Cys Tyr Asn Thr Phe  Ile Gly Glu Arg Thr  Val Gly Ala 
    1265                 1270                 1275             


Leu Gln  Val Leu Gly Thr Glu  Ala Gln Ser Ser Leu  Leu Lys Ala 
    1280                 1285                 1290             


Val Ala  Phe Phe Leu Glu Ser  Ile Ala Met His Asp  Ile Ile Ala 
    1295                 1300                 1305             


Ala Glu  Lys Cys Phe Gly Thr  Gly Ala Ala Gly Asn  Arg Thr Ser 
    1310                 1315                 1320             


Pro Gln  Glu Gly Glu Arg Tyr  Asn Tyr Ser Lys Cys  Thr Val Val 
    1325                 1330                 1335             


Val Arg  Ile Met Glu Phe Thr  Thr Thr Leu Leu Asn  Thr Ser Pro 
    1340                 1345                 1350             


Glu Gly  Trp Lys Leu Leu Lys  Lys Asp Leu Cys Asn  Thr His Leu 
    1355                 1360                 1365             


Met Arg  Val Leu Val Gln Thr  Leu Cys Glu Pro Ala  Ser Ile Gly 
    1370                 1375                 1380             


Phe Asn  Ile Gly Asp Val Gln  Val Met Ala His Leu  Pro Asp Val 
    1385                 1390                 1395             


Cys Val  Asn Leu Met Lys Ala  Leu Lys Met Ser Pro  Tyr Lys Asp 
    1400                 1405                 1410             


Ile Leu  Glu Thr His Leu Arg  Glu Lys Ile Thr Ala  Gln Ser Ile 
    1415                 1420                 1425             


Glu Glu  Leu Cys Ala Val Asn  Leu Tyr Gly Pro Asp  Ala Gln Val 
    1430                 1435                 1440             


Asp Arg  Ser Arg Leu Ala Ala  Val Val Ser Ala Cys  Lys Gln Leu 
    1445                 1450                 1455             


His Arg  Ala Gly Leu Leu His  Asn Ile Leu Pro Ser  Gln Ser Thr 
    1460                 1465                 1470             


Asp Leu  His His Ser Val Gly  Thr Glu Leu Leu Ser  Leu Val Tyr 
    1475                 1480                 1485             


Lys Gly  Ile Ala Pro Gly Asp  Glu Arg Gln Cys Leu  Pro Ser Leu 
    1490                 1495                 1500             


Asp Leu  Ser Cys Lys Gln Leu  Ala Ser Gly Leu Leu  Glu Leu Ala 
    1505                 1510                 1515             


Phe Ala  Phe Gly Gly Leu Cys  Glu Arg Leu Val Ser  Leu Leu Leu 
    1520                 1525                 1530             


Asn Pro  Ala Val Leu Ser Thr  Ala Ser Leu Gly Ser  Ser Gln Gly 
    1535                 1540                 1545             


Ser Val  Ile His Phe Ser His  Gly Glu Tyr Phe Tyr  Ser Leu Phe 
    1550                 1555                 1560             


Ser Glu  Thr Ile Asn Thr Glu  Leu Leu Lys Asn Leu  Asp Leu Ala 
    1565                 1570                 1575             


Val Leu  Glu Leu Met Gln Ser  Ser Val Asp Asn Thr  Lys Met Val 
    1580                 1585                 1590             


Ser Ala  Val Leu Asn Gly Met  Leu Asp Gln Ser Phe  Arg Glu Arg 
    1595                 1600                 1605             


Ala Asn  Gln Lys His Gln Gly  Leu Lys Leu Ala Thr  Thr Ile Leu 
    1610                 1615                 1620             


Gln His  Trp Lys Lys Cys Asp  Ser Trp Trp Ala Lys  Asp Ser Pro 
    1625                 1630                 1635             


Leu Glu  Thr Lys Met Ala Val  Leu Ala Leu Leu Ala  Lys Ile Leu 
    1640                 1645                 1650             


Gln Ile  Asp Ser Ser Val Ser  Phe Asn Thr Ser His  Gly Ser Phe 
    1655                 1660                 1665             


Pro Glu  Val Phe Thr Thr Tyr  Ile Ser Leu Leu Ala  Asp Thr Lys 
    1670                 1675                 1680             


Leu Asp  Leu His Leu Lys Gly  Gln Ala Val Thr Leu  Leu Pro Phe 
    1685                 1690                 1695             


Phe Thr  Ser Leu Thr Gly Gly  Ser Leu Glu Glu Leu  Arg Arg Val 
    1700                 1705                 1710             


Leu Glu  Gln Leu Ile Val Ala  His Phe Pro Met Gln  Ser Arg Glu 
    1715                 1720                 1725             


Phe Pro  Pro Gly Thr Pro Arg  Phe Asn Asn Tyr Val  Asp Cys Met 
    1730                 1735                 1740             


Lys Lys  Phe Leu Asp Ala Leu  Glu Leu Ser Gln Ser  Pro Met Leu 
    1745                 1750                 1755             


Leu Glu  Leu Met Thr Glu Val  Leu Cys Arg Glu Gln  Gln His Val 
    1760                 1765                 1770             


Met Glu  Glu Leu Phe Gln Ser  Ser Phe Arg Arg Ile  Ala Arg Arg 
    1775                 1780                 1785             


Gly Ser  Cys Val Thr Gln Val  Gly Leu Leu Glu Ser  Val Tyr Glu 
    1790                 1795                 1800             


Met Phe  Arg Lys Asp Asp Pro  Arg Leu Ser Phe Thr  Arg Gln Ser 
    1805                 1810                 1815             


Phe Val  Asp Arg Ser Leu Leu  Thr Leu Leu Trp His  Cys Ser Leu 
    1820                 1825                 1830             


Asp Ala  Leu Arg Glu Phe Phe  Ser Thr Ile Val Val  Asp Ala Ile 
    1835                 1840                 1845             


Asp Val  Leu Lys Ser Arg Phe  Thr Lys Leu Asn Glu  Ser Thr Phe 
    1850                 1855                 1860             


Asp Thr  Gln Ile Thr Lys Lys  Met Gly Tyr Tyr Lys  Ile Leu Asp 
    1865                 1870                 1875             


Val Met  Tyr Ser Arg Leu Pro  Lys Asp Asp Val His  Ala Lys Glu 
    1880                 1885                 1890             


Ser Lys  Ile Asn Gln Val Phe  His Gly Ser Cys Ile  Thr Glu Gly 
    1895                 1900                 1905             


Asn Glu  Leu Thr Lys Thr Leu  Ile Lys Leu Cys Tyr  Asp Ala Phe 
    1910                 1915                 1920             


Thr Glu  Asn Met Ala Gly Glu  Asn Gln Leu Leu Glu  Arg Arg Arg 
    1925                 1930                 1935             


Leu Tyr  His Cys Ala Ala Tyr  Asn Cys Ala Ile Ser  Val Ile Cys 
    1940                 1945                 1950             


Cys Val  Phe Asn Glu Leu Lys  Phe Tyr Gln Gly Phe  Leu Phe Ser 
    1955                 1960                 1965             


Glu Lys  Pro Glu Lys Asn Leu  Leu Ile Phe Glu Asn  Leu Ile Asp 
    1970                 1975                 1980             


Leu Lys  Arg Arg Tyr Asn Phe  Pro Val Glu Val Glu  Val Pro Met 
    1985                 1990                 1995             


Glu Arg  Lys Lys Lys Tyr Ile  Glu Ile Arg Lys Glu  Ala Arg Glu 
    2000                 2005                 2010             


Ala Ala  Asn Gly Asp Ser Asp  Gly Pro Ser Tyr Met  Ser Ser Leu 
    2015                 2020                 2025             


Ser Tyr  Leu Ala Asp Ser Thr  Leu Ser Glu Glu Met  Ser Gln Phe 
    2030                 2035                 2040             


Asp Phe  Ser Thr Gly Val Gln  Ser Tyr Ser Tyr Ser  Ser Gln Asp 
    2045                 2050                 2055             


Pro Arg  Pro Ala Thr Gly Arg  Phe Arg Arg Arg Glu  Gln Arg Asp 
    2060                 2065                 2070             


Pro Thr  Val His Asp Asp Val  Leu Glu Leu Glu Met  Asp Glu Leu 
    2075                 2080                 2085             


Asn Arg  His Glu Cys Met Ala  Pro Leu Thr Ala Leu  Val Lys His 
    2090                 2095                 2100             


Met His  Arg Ser Leu Gly Pro  Pro Gln Gly Glu Glu  Asp Ser Val 
    2105                 2110                 2115             


Pro Arg  Asp Leu Pro Ser Trp  Met Lys Phe Leu His  Gly Lys Leu 
    2120                 2125                 2130             


Gly Asn  Pro Ile Val Pro Leu  Asn Ile Arg Leu Phe  Leu Ala Lys 
    2135                 2140                 2145             


Leu Val  Ile Asn Thr Glu Glu  Val Phe Arg Pro Tyr  Ala Lys His 
    2150                 2155                 2160             


Trp Leu  Ser Pro Leu Leu Gln  Leu Ala Ala Ser Glu  Asn Asn Gly 
    2165                 2170                 2175             


Gly Glu  Gly Ile His Tyr Met  Val Val Glu Ile Val  Ala Thr Ile 
    2180                 2185                 2190             


Leu Ser  Trp Thr Gly Leu Ala  Thr Pro Thr Gly Val  Pro Lys Asp 
    2195                 2200                 2205             


Glu Val  Leu Ala Asn Arg Leu  Leu Asn Phe Leu Met  Lys His Val 
    2210                 2215                 2220             


Phe His  Pro Lys Arg Ala Val  Phe Arg His Asn Leu  Glu Ile Ile 
    2225                 2230                 2235             


Lys Thr  Leu Val Glu Cys Trp  Lys Asp Cys Leu Ser  Ile Pro Tyr 
    2240                 2245                 2250             


Arg Leu  Ile Phe Glu Lys Phe  Ser Gly Lys Asp Pro  Asn Ser Lys 
    2255                 2260                 2265             


Asp Asn  Ser Val Gly Ile Gln  Leu Leu Gly Ile Val  Met Ala Asn 
    2270                 2275                 2280             


Asp Leu  Pro Pro Tyr Asp Pro  Gln Cys Gly Ile Gln  Ser Ser Glu 
    2285                 2290                 2295             


Tyr Phe  Gln Ala Leu Val Asn  Asn Met Ser Phe Val  Arg Tyr Lys 
    2300                 2305                 2310             


Glu Val  Tyr Ala Ala Ala Ala  Glu Val Leu Gly Leu  Ile Leu Arg 
    2315                 2320                 2325             


Tyr Val  Met Glu Arg Lys Asn  Ile Leu Glu Glu Ser  Leu Cys Glu 
    2330                 2335                 2340             


Leu Val  Ala Lys Gln Leu Lys  Gln His Gln Asn Thr  Met Glu Asp 
    2345                 2350                 2355             


Lys Phe  Ile Val Cys Leu Asn  Lys Val Thr Lys Ser  Phe Pro Pro 
    2360                 2365                 2370             


Leu Ala  Asp Arg Phe Met Asn  Ala Val Phe Phe Leu  Leu Pro Lys 
    2375                 2380                 2385             


Phe His  Gly Val Leu Lys Thr  Leu Cys Leu Glu Val  Val Leu Cys 
    2390                 2395                 2400             


Arg Val  Glu Gly Met Thr Glu  Leu Tyr Phe Gln Leu  Lys Ser Lys 
    2405                 2410                 2415             


Asp Phe  Val Gln Val Met Arg  His Arg Asp Asp Glu  Arg Gln Lys 
    2420                 2425                 2430             


Val Cys  Leu Asp Ile Ile Tyr  Lys Met Met Pro Lys  Leu Lys Pro 
    2435                 2440                 2445             


Val Glu  Leu Arg Glu Leu Leu  Asn Pro Val Val Glu  Phe Val Ser 
    2450                 2455                 2460             


His Pro  Ser Thr Thr Cys Arg  Glu Gln Met Tyr Asn  Ile Leu Met 
    2465                 2470                 2475             


Trp Ile  His Asp Asn Tyr Arg  Asp Pro Glu Ser Glu  Thr Asp Asn 
    2480                 2485                 2490             


Asp Ser  Gln Glu Ile Phe Lys  Leu Ala Lys Asp Val  Leu Ile Gln 
    2495                 2500                 2505             


Gly Leu  Ile Asp Glu Asn Pro  Gly Leu Gln Leu Ile  Ile Arg Asn 
    2510                 2515                 2520             


Phe Trp  Ser His Glu Thr Arg  Leu Pro Ser Asn Thr  Leu Asp Arg 
    2525                 2530                 2535             


Leu Leu  Ala Leu Asn Ser Leu  Tyr Ser Pro Lys Ile  Glu Val His 
    2540                 2545                 2550             


Phe Leu  Ser Leu Ala Thr Asn  Phe Leu Leu Glu Met  Thr Ser Met 
    2555                 2560                 2565             


Ser Pro  Asp Tyr Pro Asn Pro  Met Phe Glu His Pro  Leu Ser Glu 
    2570                 2575                 2580             


Cys Glu  Phe Gln Glu Tyr Thr  Ile Asp Ser Asp Trp  Arg Phe Arg 
    2585                 2590                 2595             


Ser Thr  Val Leu Thr Pro Met  Phe Val Glu Thr Gln  Ala Ser Gln 
    2600                 2605                 2610             


Gly Thr  Leu Gln Thr Arg Thr  Gln Glu Gly Ser Leu  Ser Ala Arg 
    2615                 2620                 2625             


Trp Pro  Val Ala Gly Gln Ile  Arg Ala Thr Gln Gln  Gln His Asp 
    2630                 2635                 2640             


Phe Thr  Leu Thr Gln Thr Ala  Asp Gly Arg Ser Ser  Phe Asp Trp 
    2645                 2650                 2655             


Leu Thr  Gly Ser Ser Thr Asp  Pro Leu Val Asp His  Thr Ser Pro 
    2660                 2665                 2670             


Ser Ser  Asp Ser Leu Leu Phe  Ala His Lys Arg Ser  Glu Arg Leu 
    2675                 2680                 2685             


Gln Arg  Ala Pro Leu Lys Ser  Val Gly Pro Asp Phe  Gly Lys Lys 
    2690                 2695                 2700             


Arg Leu  Gly Leu Pro Gly Asp  Glu Val Asp Asn Lys  Val Lys Gly 
    2705                 2710                 2715             


Ala Ala  Gly Arg Thr Asp Leu  Leu Arg Leu Arg Arg  Arg Phe Met 
    2720                 2725                 2730             


Arg Asp  Gln Glu Lys Leu Ser  Leu Met Tyr Ala Arg  Lys Gly Val 
    2735                 2740                 2745             


Ala Glu  Gln Lys Arg Glu Lys  Glu Ile Lys Ser Glu  Leu Lys Met 
    2750                 2755                 2760             


Lys Gln  Asp Ala Gln Val Val  Leu Tyr Arg Ser Tyr  Arg His Gly 
    2765                 2770                 2775             


Asp Leu  Pro Asp Ile Gln Ile  Lys His Ser Ser Leu  Ile Thr Pro 
    2780                 2785                 2790             


Leu Gln  Ala Val Ala Gln Arg  Asp Pro Ile Ile Ala  Lys Gln Leu 
    2795                 2800                 2805             


Phe Ser  Ser Leu Phe Ser Gly  Ile Leu Lys Glu Met  Asp Lys Phe 
    2810                 2815                 2820             


Lys Thr  Leu Ser Glu Lys Asn  Asn Ile Thr Gln Lys  Leu Leu Gln 
    2825                 2830                 2835             


Asp Phe  Asn Arg Phe Leu Asn  Thr Thr Phe Ser Phe  Phe Pro Pro 
    2840                 2845                 2850             


Phe Val  Ser Cys Ile Gln Asp  Ile Ser Cys Gln His  Ala Ala Leu 
    2855                 2860                 2865             


Leu Ser  Leu Asp Pro Ala Ala  Val Ser Ala Gly Cys  Leu Ala Ser 
    2870                 2875                 2880             


Leu Gln  Gln Pro Val Gly Ile  Arg Leu Leu Glu Glu  Ala Leu Leu 
    2885                 2890                 2895             


Arg Leu  Leu Pro Ala Glu Leu  Pro Ala Lys Arg Val  Arg Gly Lys 
    2900                 2905                 2910             


Ala Arg  Leu Pro Pro Asp Val  Leu Arg Trp Val Glu  Leu Ala Lys 
    2915                 2920                 2925             


Leu Tyr  Arg Ser Ile Gly Glu  Tyr Asp Val Leu Arg  Gly Ile Phe 
    2930                 2935                 2940             


Thr Ser  Glu Ile Gly Thr Lys  Gln Ile Thr Gln Ser  Ala Leu Leu 
    2945                 2950                 2955             


Ala Glu  Ala Arg Ser Asp Tyr  Ser Glu Ala Ala Lys  Gln Tyr Asp 
    2960                 2965                 2970             


Glu Ala  Leu Asn Lys Gln Asp  Trp Val Asp Gly Glu  Pro Thr Glu 
    2975                 2980                 2985             


Ala Glu  Lys Asp Phe Trp Glu  Leu Ala Ser Leu Asp  Cys Tyr Asn 
    2990                 2995                 3000             


His Leu  Ala Glu Trp Lys Ser  Leu Glu Tyr Cys Ser  Thr Ala Ser 
    3005                 3010                 3015             


Ile Asp  Ser Glu Asn Pro Pro  Asp Leu Asn Lys Ile  Trp Ser Glu 
    3020                 3025                 3030             


Pro Phe  Tyr Gln Glu Thr Tyr  Leu Pro Tyr Met Ile  Arg Ser Lys 
    3035                 3040                 3045             


Leu Lys  Leu Leu Leu Gln Gly  Glu Ala Asp Gln Ser  Leu Leu Thr 
    3050                 3055                 3060             


Phe Ile  Asp Lys Ala Met His  Gly Glu Leu Gln Lys  Ala Ile Leu 
    3065                 3070                 3075             


Glu Leu  His Tyr Ser Gln Glu  Leu Ser Leu Leu Tyr  Leu Leu Gln 
    3080                 3085                 3090             


Asp Asp  Val Asp Arg Ala Lys  Tyr Tyr Ile Gln Asn  Gly Ile Gln 
    3095                 3100                 3105             


Ser Phe  Met Gln Asn Tyr Ser  Ser Ile Asp Val Leu  Leu His Gln 
    3110                 3115                 3120             


Ser Arg  Leu Thr Lys Leu Gln  Ser Val Gln Ala Leu  Thr Glu Ile 
    3125                 3130                 3135             


Gln Glu  Phe Ile Ser Phe Ile  Ser Lys Gln Gly Asn  Leu Ser Ser 
    3140                 3145                 3150             


Gln Val  Pro Leu Lys Arg Leu  Leu Asn Thr Trp Thr  Asn Arg Tyr 
    3155                 3160                 3165             


Pro Asp  Ala Lys Met Asp Pro  Met Asn Ile Trp Asp  Asp Ile Ile 
    3170                 3175                 3180             


Thr Asn  Arg Cys Phe Phe Leu  Ser Lys Ile Glu Glu  Lys Leu Thr 
    3185                 3190                 3195             


Pro Leu  Pro Glu Asp Asn Ser  Met Asn Val Asp Gln  Asp Gly Asp 
    3200                 3205                 3210             


Pro Ser  Asp Arg Met Glu Val  Gln Glu Gln Glu Glu  Asp Ile Ser 
    3215                 3220                 3225             


Ser Leu  Ile Arg Ser Cys Lys  Phe Ser Met Lys Met  Lys Met Ile 
    3230                 3235                 3240             


Asp Ser  Ala Arg Lys Gln Asn  Asn Phe Ser Leu Ala  Met Lys Leu 
    3245                 3250                 3255             


Leu Lys  Glu Leu His Lys Glu  Ser Lys Thr Arg Asp  Asp Trp Leu 
    3260                 3265                 3270             


Val Ser  Trp Val Gln Ser Tyr  Cys Arg Leu Ser His  Cys Arg Ser 
    3275                 3280                 3285             


Arg Ser  Gln Gly Cys Ser Glu  Gln Val Leu Thr Val  Leu Lys Thr 
    3290                 3295                 3300             


Val Ser  Leu Leu Asp Glu Asn  Asn Val Ser Ser Tyr  Leu Ser Lys 
    3305                 3310                 3315             


Asn Ile  Leu Ala Phe Arg Asp  Gln Asn Ile Leu Leu  Gly Thr Thr 
    3320                 3325                 3330             


Tyr Arg  Ile Ile Ala Asn Ala  Leu Ser Ser Glu Pro  Ala Cys Leu 
    3335                 3340                 3345             


Ala Glu  Ile Glu Glu Asp Lys  Ala Arg Arg Ile Leu  Glu Leu Ser 
    3350                 3355                 3360             


Gly Ser  Ser Ser Glu Asp Ser  Glu Lys Val Ile Ala  Gly Leu Tyr 
    3365                 3370                 3375             


Gln Arg  Ala Phe Gln His Leu  Ser Glu Ala Val Gln  Ala Ala Glu 
    3380                 3385                 3390             


Glu Glu  Ala Gln Pro Pro Ser  Trp Ser Cys Gly Pro  Ala Ala Gly 
    3395                 3400                 3405             


Val Ile  Asp Ala Tyr Met Thr  Leu Ala Asp Phe Cys  Asp Gln Gln 
    3410                 3415                 3420             


Leu Arg  Lys Glu Glu Glu Asn  Ala Ser Val Ile Asp  Ser Ala Glu 
    3425                 3430                 3435             


Leu Gln  Ala Tyr Pro Ala Leu  Val Val Glu Lys Met  Leu Lys Ala 
    3440                 3445                 3450             


Leu Lys  Leu Asn Ser Asn Glu  Ala Arg Leu Lys Phe  Pro Arg Leu 
    3455                 3460                 3465             


Leu Gln  Ile Ile Glu Arg Tyr  Pro Glu Glu Thr Leu  Ser Leu Met 
    3470                 3475                 3480             


Thr Lys  Glu Ile Ser Ser Val  Pro Cys Trp Gln Phe  Ile Ser Trp 
    3485                 3490                 3495             


Ile Ser  His Met Val Ala Leu  Leu Asp Lys Asp Gln  Ala Val Ala 
    3500                 3505                 3510             


Val Gln  His Ser Val Glu Glu  Ile Thr Asp Asn Tyr  Pro Gln Ala 
    3515                 3520                 3525             


Ile Val  Tyr Pro Phe Ile Ile  Ser Ser Glu Ser Tyr  Ser Phe Lys 
    3530                 3535                 3540             


Asp Thr  Ser Thr Gly His Lys  Asn Lys Glu Phe Val  Ala Arg Ile 
    3545                 3550                 3555             


Lys Ser  Lys Leu Asp Gln Gly  Gly Val Ile Gln Asp  Phe Ile Asn 
    3560                 3565                 3570             


Ala Leu  Asp Gln Leu Ser Asn  Pro Glu Leu Leu Phe  Lys Asp Trp 
    3575                 3580                 3585             


Ser Asn  Asp Val Arg Ala Glu  Leu Ala Lys Thr Pro  Val Asn Lys 
    3590                 3595                 3600             


Lys Asn  Ile Glu Lys Met Tyr  Glu Arg Met Tyr Ala  Ala Leu Gly 
    3605                 3610                 3615             


Asp Pro  Lys Ala Pro Gly Leu  Gly Ala Phe Arg Arg  Lys Phe Ile 
    3620                 3625                 3630             


Gln Thr  Phe Gly Lys Glu Phe  Asp Lys His Phe Gly  Lys Gly Gly 
    3635                 3640                 3645             


Ser Lys  Leu Leu Arg Met Lys  Leu Ser Asp Phe Asn  Asp Ile Thr 
    3650                 3655                 3660             


Asn Met  Leu Leu Leu Lys Met  Asn Lys Asp Ser Lys  Pro Pro Gly 
    3665                 3670                 3675             


Asn Leu  Lys Glu Cys Ser Pro  Trp Met Ser Asp Phe  Lys Val Glu 
    3680                 3685                 3690             


Phe Leu  Arg Asn Glu Leu Glu  Ile Pro Gly Gln Tyr  Asp Gly Arg 
    3695                 3700                 3705             


Gly Lys  Pro Leu Pro Glu Tyr  His Val Arg Ile Ala  Gly Phe Asp 
    3710                 3715                 3720             


Glu Arg  Val Thr Val Met Ala  Ser Leu Arg Arg Pro  Lys Arg Ile 
    3725                 3730                 3735             


Ile Ile  Arg Gly His Asp Glu  Arg Glu His Pro Phe  Leu Val Lys 
    3740                 3745                 3750             


Gly Gly  Glu Asp Leu Arg Gln  Asp Gln Arg Val Glu  Gln Leu Phe 
    3755                 3760                 3765             


Gln Val  Met Asn Gly Ile Leu  Ala Gln Asp Ser Ala  Cys Ser Gln 
    3770                 3775                 3780             


Arg Ala  Leu Gln Leu Arg Thr  Tyr Ser Val Val Pro  Met Thr Ser 
    3785                 3790                 3795             


Arg Leu  Gly Leu Ile Glu Trp  Leu Glu Asn Thr Val  Thr Leu Lys 
    3800                 3805                 3810             


Asp Leu  Leu Leu Asn Thr Met  Ser Gln Glu Glu Lys  Ala Ala Tyr 
    3815                 3820                 3825             


Leu Ser  Asp Pro Arg Ala Pro  Pro Cys Glu Tyr Lys  Asp Trp Leu 
    3830                 3835                 3840             


Thr Lys  Met Ser Gly Lys His  Asp Val Gly Ala Tyr  Met Leu Met 
    3845                 3850                 3855             


Tyr Lys  Gly Ala Asn Arg Thr  Glu Thr Val Thr Ser  Phe Arg Lys 
    3860                 3865                 3870             


Arg Glu  Ser Lys Val Pro Ala  Asp Leu Leu Lys Arg  Ala Phe Val 
    3875                 3880                 3885             


Arg Met  Ser Thr Ser Pro Glu  Ala Phe Leu Ala Leu  Arg Ser His 
    3890                 3895                 3900             


Phe Ala  Ser Ser His Ala Leu  Ile Cys Ile Ser His  Trp Ile Leu 
    3905                 3910                 3915             


Gly Ile  Gly Asp Arg His Leu  Asn Asn Phe Met Val  Ala Met Glu 
    3920                 3925                 3930             


Thr Gly  Gly Val Ile Gly Ile  Asp Phe Gly His Ala  Phe Gly Ser 
    3935                 3940                 3945             


Ala Thr  Gln Phe Leu Pro Val  Pro Glu Leu Met Pro  Phe Arg Leu 
    3950                 3955                 3960             


Thr Arg  Gln Phe Ile Asn Leu  Met Leu Pro Met Lys  Glu Thr Gly 
    3965                 3970                 3975             


Leu Met  Tyr Ser Ile Met Val  His Ala Leu Arg Ala  Phe Arg Ser 
    3980                 3985                 3990             


Asp Pro  Gly Leu Leu Thr Asn  Thr Met Asp Val Phe  Val Lys Glu 
    3995                 4000                 4005             


Pro Ser  Phe Asp Trp Lys Asn  Phe Glu Gln Lys Met  Leu Lys Lys 
    4010                 4015                 4020             


Gly Gly  Ser Trp Ile Gln Glu  Ile Asn Val Ala Glu  Lys Asn Trp 
    4025                 4030                 4035             


Tyr Pro  Arg Gln Lys Ile Cys  Tyr Ala Lys Arg Lys  Leu Ala Gly 
    4040                 4045                 4050             


Ala Asn  Pro Ala Val Ile Thr  Cys Asp Glu Leu Leu  Leu Gly His 
    4055                 4060                 4065             


Glu Lys  Ala Pro Ala Phe Arg  Asp Tyr Val Ala Val  Ala Arg Gly 
    4070                 4075                 4080             


Ser Lys  Asp His Asn Ile Arg  Ala Gln Glu Pro Glu  Ser Gly Leu 
    4085                 4090                 4095             


Ser Glu  Glu Thr Gln Val Lys  Cys Leu Met Asp Gln  Ala Thr Asp 
    4100                 4105                 4110             


Pro Asn  Ile Leu Gly Arg Thr  Trp Glu Gly Trp Glu  Pro Trp Met 
    4115                 4120                 4125             


<210>  4123
<211>  475
<212>  PRT
<213>  homo sapiens

<400>  4123

Met Glu Arg Asp Glu Pro Pro Pro Ser Gly Gly Gly Gly Gly Gly Gly 
1               5                   10                  15      


Ser Ala Gly Phe Leu Glu Pro Pro Ala Ala Leu Pro Pro Pro Pro Arg 
            20                  25                  30          


Asn Gly Phe Cys Gln Asp Glu Leu Ala Glu Leu Asp Pro Gly Thr Asn 
        35                  40                  45              


Asp Arg Ala Glu Gln Arg Thr Cys Leu Ile Cys Gly Asp Arg Ala Thr 
    50                  55                  60                  


Gly Leu His Tyr Gly Ile Ile Ser Cys Glu Gly Cys Lys Gly Phe Phe 
65                  70                  75                  80  


Lys Arg Ser Ile Cys Asn Lys Arg Val Tyr Arg Cys Ser Arg Asp Lys 
                85                  90                  95      


Asn Cys Val Met Ser Arg Lys Gln Arg Asn Arg Cys Gln Tyr Cys Arg 
            100                 105                 110         


Leu Leu Lys Cys Leu Gln Met Gly Met Asn Arg Lys Ala Ile Arg Glu 
        115                 120                 125             


Asp Gly Met Pro Gly Gly Arg Asn Lys Ser Ile Gly Pro Val Gln Ile 
    130                 135                 140                 


Ser Glu Glu Glu Ile Glu Arg Ile Met Ser Gly Gln Glu Phe Glu Glu 
145                 150                 155                 160 


Glu Ala Asn His Trp Ser Asn His Gly Asp Ser Asp His Ser Ser Pro 
                165                 170                 175     


Gly Asn Arg Ala Ser Glu Ser Asn Gln Pro Ser Pro Gly Ser Thr Leu 
            180                 185                 190         


Ser Ser Arg Ser Val Glu Leu Asn Gly Phe Met Ala Phe Arg Glu Gln 
        195                 200                 205             


Tyr Met Gly Met Ser Val Pro Pro His Tyr Gln Tyr Ile Pro His Leu 
    210                 215                 220                 


Phe Ser Tyr Ser Gly His Ser Pro Leu Leu Pro Gln Gln Ala Arg Ser 
225                 230                 235                 240 


Leu Asp Pro Gln Ser Tyr Ser Leu Ile His Gln Leu Leu Ser Ala Glu 
                245                 250                 255     


Asp Leu Glu Pro Leu Gly Thr Pro Met Leu Ile Glu Asp Gly Tyr Ala 
            260                 265                 270         


Val Thr Gln Ala Glu Leu Phe Ala Leu Leu Cys Arg Leu Ala Asp Glu 
        275                 280                 285             


Leu Leu Phe Arg Gln Ile Ala Trp Ile Lys Lys Leu Pro Phe Phe Cys 
    290                 295                 300                 


Glu Leu Ser Ile Lys Asp Tyr Thr Cys Leu Leu Ser Ser Thr Trp Gln 
305                 310                 315                 320 


Glu Leu Ile Leu Leu Ser Ser Leu Thr Val Tyr Ser Lys Gln Ile Phe 
                325                 330                 335     


Gly Glu Leu Ala Asp Val Thr Ala Lys Tyr Ser Pro Ser Asp Glu Glu 
            340                 345                 350         


Leu His Arg Phe Ser Asp Glu Gly Met Glu Val Ile Glu Arg Leu Ile 
        355                 360                 365             


Tyr Leu Tyr His Lys Phe His Gln Leu Lys Val Ser Asn Glu Glu Tyr 
    370                 375                 380                 


Ala Cys Met Lys Ala Ile Asn Phe Leu Asn Gln Asp Ile Arg Gly Leu 
385                 390                 395                 400 


Thr Ser Ala Ser Gln Leu Glu Gln Leu Asn Lys Arg Tyr Trp Tyr Ile 
                405                 410                 415     


Cys Gln Asp Phe Thr Glu Tyr Lys Tyr Thr His Gln Pro Asn Arg Phe 
            420                 425                 430         


Pro Asp Leu Met Met Cys Leu Pro Glu Ile Arg Tyr Ile Ala Gly Lys 
        435                 440                 445             


Met Val Asn Val Pro Leu Glu Gln Leu Pro Leu Leu Phe Lys Val Val 
    450                 455                 460                 


Leu His Ser Cys Lys Thr Ser Val Gly Lys Glu 
465                 470                 475 


<210>  4124
<211>  500
<212>  PRT
<213>  homo sapiens

<400>  4124

Met Ala Thr Val Ile Pro Gly Asp Leu Ser Glu Val Arg Asp Thr Gln 
1               5                   10                  15      


Lys Val Pro Ser Gly Lys Arg Lys Arg Gly Glu Thr Lys Pro Arg Lys 
            20                  25                  30          


Asn Phe Pro Cys Gln Leu Cys Asp Lys Ala Phe Asn Ser Val Glu Lys 
        35                  40                  45              


Leu Lys Val His Ser Tyr Ser His Thr Gly Glu Arg Pro Tyr Lys Cys 
    50                  55                  60                  


Ile Gln Gln Asp Cys Thr Lys Ala Phe Val Ser Lys Tyr Lys Leu Gln 
65                  70                  75                  80  


Arg His Met Ala Thr His Ser Pro Glu Lys Thr His Lys Cys Asn Tyr 
                85                  90                  95      


Cys Glu Lys Met Phe His Arg Lys Asp His Leu Lys Asn His Leu His 
            100                 105                 110         


Thr His Asp Pro Asn Lys Glu Thr Phe Lys Cys Glu Glu Cys Gly Lys 
        115                 120                 125             


Asn Tyr Asn Thr Lys Leu Gly Phe Lys Arg His Leu Ala Leu His Ala 
    130                 135                 140                 


Ala Thr Ser Gly Asp Leu Thr Cys Lys Val Cys Leu Gln Thr Phe Glu 
145                 150                 155                 160 


Ser Thr Gly Val Leu Leu Glu His Leu Lys Ser His Ala Gly Lys Ser 
                165                 170                 175     


Ser Gly Gly Val Lys Glu Lys Lys His Gln Cys Glu His Cys Asp Arg 
            180                 185                 190         


Arg Phe Tyr Thr Arg Lys Asp Val Arg Arg His Met Val Val His Thr 
        195                 200                 205             


Gly Arg Lys Asp Phe Leu Cys Gln Tyr Cys Ala Gln Arg Phe Gly Arg 
    210                 215                 220                 


Lys Asp His Leu Thr Arg His Met Lys Lys Ser His Asn Gln Glu Leu 
225                 230                 235                 240 


Leu Lys Val Lys Thr Glu Pro Val Asp Phe Leu Asp Pro Phe Thr Cys 
                245                 250                 255     


Asn Val Ser Val Pro Ile Lys Asp Glu Leu Leu Pro Val Met Ser Leu 
            260                 265                 270         


Pro Ser Ser Glu Leu Leu Ser Lys Pro Phe Thr Asn Thr Leu Gln Leu 
        275                 280                 285             


Asn Leu Tyr Asn Thr Pro Phe Gln Ser Met Gln Ser Ser Gly Ser Ala 
    290                 295                 300                 


His Gln Met Ile Thr Thr Leu Pro Leu Gly Met Thr Cys Pro Ile Asp 
305                 310                 315                 320 


Met Asp Thr Val His Pro Ser His His Leu Ser Phe Lys Tyr Pro Phe 
                325                 330                 335     


Ser Ser Thr Ser Tyr Ala Ile Ser Ile Pro Glu Lys Glu Gln Pro Leu 
            340                 345                 350         


Lys Gly Glu Ile Glu Ser Tyr Leu Met Glu Leu Gln Gly Gly Val Pro 
        355                 360                 365             


Ser Ser Ser Gln Asp Ser Gln Ala Ser Ser Ser Ser Lys Leu Gly Leu 
    370                 375                 380                 


Asp Pro Gln Ile Gly Ser Leu Asp Asp Gly Ala Gly Asp Leu Ser Leu 
385                 390                 395                 400 


Ser Lys Ser Ser Ile Ser Ile Ser Asp Pro Leu Asn Thr Pro Ala Leu 
                405                 410                 415     


Asp Phe Ser Gln Leu Phe Asn Phe Ile Pro Leu Asn Gly Pro Pro Tyr 
            420                 425                 430         


Asn Pro Leu Ser Val Gly Ser Leu Gly Met Ser Tyr Ser Gln Glu Glu 
        435                 440                 445             


Ala His Ser Ser Val Ser Gln Leu Pro Pro Gln Thr Gln Asp Leu Gln 
    450                 455                 460                 


Asp Pro Ala Asn Thr Ile Gly Leu Gly Ser Leu His Ser Leu Ser Ala 
465                 470                 475                 480 


Ala Phe Thr Ser Ser Leu Ser Thr Ser Thr Thr Leu Pro Arg Phe His 
                485                 490                 495     


Gln Ala Phe Gln 
            500 


<210>  4125
<211>  418
<212>  PRT
<213>  homo sapiens

<400>  4125

Met Ala Thr His Ser Pro Glu Lys Thr His Lys Cys Asn Tyr Cys Glu 
1               5                   10                  15      


Lys Met Phe His Arg Lys Asp His Leu Lys Asn His Leu His Thr His 
            20                  25                  30          


Asp Pro Asn Lys Glu Thr Phe Lys Cys Glu Glu Cys Gly Lys Asn Tyr 
        35                  40                  45              


Asn Thr Lys Leu Gly Phe Lys Arg His Leu Ala Leu His Ala Ala Thr 
    50                  55                  60                  


Ser Gly Asp Leu Thr Cys Lys Val Cys Leu Gln Thr Phe Glu Ser Thr 
65                  70                  75                  80  


Gly Val Leu Leu Glu His Leu Lys Ser His Ala Gly Lys Ser Ser Gly 
                85                  90                  95      


Gly Val Lys Glu Lys Lys His Gln Cys Glu His Cys Asp Arg Arg Phe 
            100                 105                 110         


Tyr Thr Arg Lys Asp Val Arg Arg His Met Val Val His Thr Gly Arg 
        115                 120                 125             


Lys Asp Phe Leu Cys Gln Tyr Cys Ala Gln Arg Phe Gly Arg Lys Asp 
    130                 135                 140                 


His Leu Thr Arg His Met Lys Lys Ser His Asn Gln Glu Leu Leu Lys 
145                 150                 155                 160 


Val Lys Thr Glu Pro Val Asp Phe Leu Asp Pro Phe Thr Cys Asn Val 
                165                 170                 175     


Ser Val Pro Ile Lys Asp Glu Leu Leu Pro Val Met Ser Leu Pro Ser 
            180                 185                 190         


Ser Glu Leu Leu Ser Lys Pro Phe Thr Asn Thr Leu Gln Leu Asn Leu 
        195                 200                 205             


Tyr Asn Thr Pro Phe Gln Ser Met Gln Ser Ser Gly Ser Ala His Gln 
    210                 215                 220                 


Met Ile Thr Thr Leu Pro Leu Gly Met Thr Cys Pro Ile Asp Met Asp 
225                 230                 235                 240 


Thr Val His Pro Ser His His Leu Ser Phe Lys Tyr Pro Phe Ser Ser 
                245                 250                 255     


Thr Ser Tyr Ala Ile Ser Ile Pro Glu Lys Glu Gln Pro Leu Lys Gly 
            260                 265                 270         


Glu Ile Glu Ser Tyr Leu Met Glu Leu Gln Gly Gly Val Pro Ser Ser 
        275                 280                 285             


Ser Gln Asp Ser Gln Ala Ser Ser Ser Ser Lys Leu Gly Leu Asp Pro 
    290                 295                 300                 


Gln Ile Gly Ser Leu Asp Asp Gly Ala Gly Asp Leu Ser Leu Ser Lys 
305                 310                 315                 320 


Ser Ser Ile Ser Ile Ser Asp Pro Leu Asn Thr Pro Ala Leu Asp Phe 
                325                 330                 335     


Ser Gln Leu Phe Asn Phe Ile Pro Leu Asn Gly Pro Pro Tyr Asn Pro 
            340                 345                 350         


Leu Ser Val Gly Ser Leu Gly Met Ser Tyr Ser Gln Glu Glu Ala His 
        355                 360                 365             


Ser Ser Val Ser Gln Leu Pro Pro Gln Thr Gln Asp Leu Gln Asp Pro 
    370                 375                 380                 


Ala Asn Thr Ile Gly Leu Gly Ser Leu His Ser Leu Ser Ala Ala Phe 
385                 390                 395                 400 


Thr Ser Ser Leu Ser Thr Ser Thr Thr Leu Pro Arg Phe His Gln Ala 
                405                 410                 415     


Phe Gln 
        


<210>  4126
<211>  837
<212>  PRT
<213>  homo sapiens

<400>  4126

Met Phe Lys Cys Trp Ser Val Val Leu Val Leu Gly Phe Ile Phe Leu 
1               5                   10                  15      


Glu Ser Glu Gly Arg Pro Thr Lys Glu Gly Gly Tyr Gly Leu Lys Ser 
            20                  25                  30          


Tyr Gln Pro Leu Met Arg Leu Arg His Lys Glu Lys Asn Gln Glu Ser 
        35                  40                  45              


Ser Arg Val Lys Gly Phe Met Ile Gln Asp Gly Pro Phe Gly Ser Cys 
    50                  55                  60                  


Glu Asn Lys Tyr Cys Gly Leu Gly Arg His Cys Val Thr Ser Arg Glu 
65                  70                  75                  80  


Thr Gly Gln Ala Glu Cys Ala Cys Met Asp Leu Cys Lys Arg His Tyr 
                85                  90                  95      


Lys Pro Val Cys Gly Ser Asp Gly Glu Phe Tyr Glu Asn His Cys Glu 
            100                 105                 110         


Val His Arg Ala Ala Cys Leu Lys Lys Gln Lys Ile Thr Ile Val His 
        115                 120                 125             


Asn Glu Asp Cys Phe Phe Lys Gly Asp Lys Cys Lys Thr Thr Glu Tyr 
    130                 135                 140                 


Ser Lys Met Lys Asn Met Leu Leu Asp Leu Gln Asn Gln Lys Tyr Ile 
145                 150                 155                 160 


Met Gln Glu Asn Glu Asn Pro Asn Gly Asp Asp Ile Ser Arg Lys Lys 
                165                 170                 175     


Leu Leu Val Asp Gln Met Phe Lys Tyr Phe Asp Ala Asp Ser Asn Gly 
            180                 185                 190         


Leu Val Asp Ile Asn Glu Leu Thr Gln Val Ile Lys Gln Glu Glu Leu 
        195                 200                 205             


Gly Lys Asp Leu Phe Asp Cys Thr Leu Tyr Val Leu Leu Lys Tyr Asp 
    210                 215                 220                 


Asp Phe Asn Ala Asp Lys His Leu Ala Leu Glu Glu Phe Tyr Arg Ala 
225                 230                 235                 240 


Phe Gln Val Ile Gln Leu Ser Leu Pro Glu Asp Gln Lys Leu Ser Ile 
                245                 250                 255     


Thr Ala Ala Thr Val Gly Gln Ser Ala Val Leu Ser Cys Ala Ile Gln 
            260                 265                 270         


Gly Thr Leu Arg Pro Pro Ile Ile Trp Lys Arg Asn Asn Ile Ile Leu 
        275                 280                 285             


Asn Asn Leu Asp Leu Glu Asp Ile Asn Asp Phe Gly Asp Asp Gly Ser 
    290                 295                 300                 


Leu Tyr Ile Thr Lys Val Thr Thr Thr His Val Gly Asn Tyr Thr Cys 
305                 310                 315                 320 


Tyr Ala Asp Gly Tyr Glu Gln Val Tyr Gln Thr His Ile Phe Gln Val 
                325                 330                 335     


Asn Val Pro Pro Val Ile Arg Val Tyr Pro Glu Ser Gln Ala Arg Glu 
            340                 345                 350         


Pro Gly Val Thr Ala Ser Leu Arg Cys His Ala Glu Gly Ile Pro Lys 
        355                 360                 365             


Pro Gln Leu Gly Trp Leu Lys Asn Gly Ile Asp Ile Thr Pro Lys Leu 
    370                 375                 380                 


Ser Lys Gln Leu Thr Leu Gln Ala Asn Gly Ser Glu Val His Ile Ser 
385                 390                 395                 400 


Asn Val Arg Tyr Glu Asp Thr Gly Ala Tyr Thr Cys Ile Ala Lys Asn 
                405                 410                 415     


Glu Ala Gly Val Asp Glu Asp Ile Ser Ser Leu Phe Val Glu Asp Ser 
            420                 425                 430         


Ala Arg Lys Thr Arg Leu Gly Ile Gly Asn Met Phe Tyr Val Phe Tyr 
        435                 440                 445             


Glu Asp Gly Ile Lys Val Ile Gln Pro Ile Glu Cys Glu Phe Gln Arg 
    450                 455                 460                 


His Ile Lys Pro Ser Glu Lys Leu Leu Gly Phe Gln Asp Glu Val Cys 
465                 470                 475                 480 


Pro Lys Ala Glu Gly Asp Glu Val Gln Arg Cys Val Trp Ala Ser Ala 
                485                 490                 495     


Val Asn Val Lys Asp Lys Phe Ile Tyr Val Ala Gln Pro Thr Leu Asp 
            500                 505                 510         


Arg Val Leu Ile Val Asp Val Gln Ser Gln Lys Val Val Gln Ala Val 
        515                 520                 525             


Ser Thr Asp Pro Val Pro Val Lys Leu His Tyr Asp Lys Ser His Asp 
    530                 535                 540                 


Gln Val Trp Val Leu Ser Trp Gly Thr Leu Glu Lys Thr Ser Pro Thr 
545                 550                 555                 560 


Leu Gln Val Ile Thr Leu Ala Ser Gly Asn Val Pro His His Thr Ile 
                565                 570                 575     


His Thr Gln Pro Val Gly Lys Gln Phe Asp Arg Val Asp Asp Phe Phe 
            580                 585                 590         


Ile Pro Thr Thr Thr Leu Ile Ile Thr His Met Arg Phe Gly Phe Ile 
        595                 600                 605             


Leu His Lys Asp Glu Ala Ala Leu Gln Lys Ile Asp Leu Glu Thr Met 
    610                 615                 620                 


Ser Tyr Ile Lys Thr Ile Asn Leu Lys Asp Tyr Lys Cys Val Pro Gln 
625                 630                 635                 640 


Ser Leu Ala Tyr Thr His Leu Gly Gly Tyr Tyr Phe Ile Gly Cys Lys 
                645                 650                 655     


Pro Asp Ser Thr Gly Ala Val Ser Pro Gln Val Met Val Asp Gly Val 
            660                 665                 670         


Thr Asp Ser Val Ile Gly Phe Asn Ser Asp Val Thr Gly Thr Pro Tyr 
        675                 680                 685             


Val Ser Pro Asp Gly His Tyr Leu Val Ser Ile Asn Asp Val Lys Gly 
    690                 695                 700                 


Leu Val Arg Val Gln Tyr Ile Thr Ile Arg Gly Glu Ile Gln Glu Ala 
705                 710                 715                 720 


Phe Asp Ile Tyr Thr Asn Leu His Ile Ser Asp Leu Ala Phe Gln Pro 
                725                 730                 735     


Ser Phe Thr Glu Ala His Gln Tyr Asn Ile Tyr Gly Ser Ser Ser Thr 
            740                 745                 750         


Gln Thr Asp Val Leu Phe Val Glu Leu Ser Ser Gly Lys Val Lys Met 
        755                 760                 765             


Ile Lys Ser Leu Lys Glu Pro Leu Lys Ala Glu Glu Trp Pro Trp Asn 
    770                 775                 780                 


Arg Lys Asn Arg Gln Ile Gln Asp Ser Gly Leu Phe Gly Gln Tyr Leu 
785                 790                 795                 800 


Met Thr Pro Ser Lys Asp Ser Leu Phe Ile Leu Asp Gly Arg Leu Asn 
                805                 810                 815     


Lys Leu Asn Cys Glu Ile Thr Glu Val Glu Lys Gly Asn Thr Val Ile 
            820                 825                 830         


Trp Val Gly Asp Ala 
        835         


<210>  4127
<211>  740
<212>  PRT
<213>  homo sapiens

<400>  4127

Met Ser Ser Glu Cys Asp Gly Gly Ser Lys Ala Val Met Asn Gly Leu 
1               5                   10                  15      


Ala Pro Gly Ser Asn Gly Gln Asp Lys Asp Met Asp Pro Thr Lys Ile 
            20                  25                  30          


Cys Thr Gly Lys Gly Ala Val Thr Leu Arg Ala Ser Ser Ser Tyr Arg 
        35                  40                  45              


Glu Thr Pro Ser Ser Ser Pro Ala Ser Pro Gln Glu Thr Arg Gln His 
    50                  55                  60                  


Glu Ser Lys Pro Asp Glu Trp Arg Leu Ser Ser Ser Ala Asp Ala Asn 
65                  70                  75                  80  


Gly Asn Ala Gln Pro Ser Ser Leu Ala Ala Lys Gly Tyr Arg Ser Val 
                85                  90                  95      


His Pro Asn Leu Pro Ser Asp Lys Ser Gln Asp Ser Ser Pro Leu Leu 
            100                 105                 110         


Asn Glu Val Ser Ser Ser Leu Ile Gly Thr Asp Ser Gln Ala Phe Pro 
        115                 120                 125             


Ser Val Ser Lys Pro Ser Ser Ala Tyr Pro Ser Thr Thr Ile Val Asn 
    130                 135                 140                 


Pro Thr Ile Val Leu Leu Gln His Asn Arg Glu Gln Gln Lys Arg Leu 
145                 150                 155                 160 


Ser Ser Leu Ser Asp Pro Val Ser Glu Arg Arg Val Gly Glu Gln Asp 
                165                 170                 175     


Ser Ala Pro Thr Gln Glu Lys Pro Thr Ser Pro Gly Lys Ala Ile Glu 
            180                 185                 190         


Lys Arg Ala Lys Asp Asp Ser Arg Arg Val Val Lys Ser Thr Gln Asp 
        195                 200                 205             


Leu Ser Asp Val Ser Met Asp Glu Val Gly Ile Pro Leu Arg Asn Thr 
    210                 215                 220                 


Glu Arg Ser Lys Asp Trp Tyr Lys Thr Met Phe Lys Gln Ile His Lys 
225                 230                 235                 240 


Leu Asn Arg Asp Asp Asp Ser Asp Leu Tyr Ser Pro Arg Tyr Ser Phe 
                245                 250                 255     


Ser Glu Asp Thr Lys Ser Pro Leu Ser Val Pro Arg Ser Lys Ser Glu 
            260                 265                 270         


Met Ser Tyr Ile Asp Gly Glu Lys Val Val Lys Arg Ser Ala Thr Leu 
        275                 280                 285             


Pro Leu Pro Ala Arg Ser Ser Ser Leu Lys Ser Ser Ser Glu Arg Asn 
    290                 295                 300                 


Asp Trp Glu Pro Pro Asp Lys Lys Val Asp Thr Arg Lys Tyr Arg Ala 
305                 310                 315                 320 


Glu Pro Lys Ser Ile Tyr Glu Tyr Gln Pro Gly Lys Ser Ser Val Leu 
                325                 330                 335     


Thr Asn Glu Lys Met Ser Ser Ala Ile Ser Pro Thr Pro Glu Ile Ser 
            340                 345                 350         


Ser Glu Thr Pro Gly Tyr Ile Tyr Ser Ser Asn Phe His Ala Val Lys 
        355                 360                 365             


Arg Glu Ser Asp Gly Ala Pro Gly Asp Leu Thr Ser Leu Glu Asn Glu 
    370                 375                 380                 


Arg Gln Ile Tyr Lys Ser Val Leu Glu Gly Gly Asp Ile Pro Leu Gln 
385                 390                 395                 400 


Gly Leu Ser Gly Leu Lys Arg Pro Ser Ser Ser Ala Ser Thr Lys Asp 
                405                 410                 415     


Ser Glu Ser Pro Arg His Phe Ile Pro Ala Asp Tyr Leu Glu Ser Thr 
            420                 425                 430         


Glu Glu Phe Ile Arg Arg Arg His Asp Asp Lys Glu Lys Leu Leu Ala 
        435                 440                 445             


Asp Gln Arg Arg Leu Lys Arg Glu Gln Glu Glu Ala Asp Ile Ala Ala 
    450                 455                 460                 


Arg Arg His Thr Gly Val Ile Pro Thr His His Gln Phe Ile Thr Asn 
465                 470                 475                 480 


Glu Arg Phe Gly Asp Leu Leu Asn Ile Asp Asp Thr Ala Lys Arg Lys 
                485                 490                 495     


Ser Gly Ser Glu Met Arg Pro Ala Arg Ala Lys Phe Asp Phe Lys Ala 
            500                 505                 510         


Gln Thr Leu Lys Glu Leu Pro Leu Gln Lys Gly Asp Ile Val Tyr Ile 
        515                 520                 525             


Tyr Lys Gln Ile Asp Gln Asn Trp Tyr Glu Gly Glu His His Gly Arg 
    530                 535                 540                 


Val Gly Ile Phe Pro Arg Thr Tyr Ile Glu Leu Leu Pro Pro Ala Glu 
545                 550                 555                 560 


Lys Ala Gln Pro Lys Lys Leu Thr Pro Val Gln Val Leu Glu Tyr Gly 
                565                 570                 575     


Glu Ala Ile Ala Lys Phe Asn Phe Asn Gly Asp Thr Gln Val Glu Met 
            580                 585                 590         


Ser Phe Arg Lys Gly Glu Arg Ile Thr Leu Leu Arg Gln Val Asp Glu 
        595                 600                 605             


Asn Trp Tyr Glu Gly Arg Ile Pro Gly Thr Ser Arg Gln Gly Ile Phe 
    610                 615                 620                 


Pro Ile Thr Tyr Val Asp Val Ile Lys Arg Pro Leu Val Lys Asn Pro 
625                 630                 635                 640 


Val Asp Tyr Met Asp Leu Pro Phe Ser Ser Ser Pro Ser Arg Ser Ala 
                645                 650                 655     


Thr Ala Ser Pro Gln Gln Pro Gln Ala Gln Gln Arg Arg Val Thr Pro 
            660                 665                 670         


Asp Arg Ser Gln Thr Ser Gln Asp Leu Phe Ser Tyr Gln Ala Leu Tyr 
        675                 680                 685             


Ser Tyr Ile Pro Gln Asn Asp Asp Glu Leu Glu Leu Arg Asp Gly Asp 
    690                 695                 700                 


Ile Val Asp Val Met Glu Lys Cys Asp Asp Gly Trp Phe Val Gly Thr 
705                 710                 715                 720 


Ser Arg Arg Thr Lys Gln Phe Gly Thr Phe Pro Gly Asn Tyr Val Lys 
                725                 730                 735     


Pro Leu Tyr Leu 
            740 


<210>  4128
<211>  711
<212>  PRT
<213>  homo sapiens

<400>  4128

Met Glu Ser Gly Ala Val Leu Leu Glu Ser Lys Ser Ser Pro Phe Asn 
1               5                   10                  15      


Leu Leu His Glu Met His Glu Leu Arg Leu Leu Gly His Leu Cys Asp 
            20                  25                  30          


Val Thr Val Ser Val Glu Tyr Gln Gly Val Arg Lys Asp Phe Met Ala 
        35                  40                  45              


His Lys Ala Val Leu Ala Ala Thr Ser Lys Phe Phe Lys Glu Val Phe 
    50                  55                  60                  


Leu Asn Glu Lys Ser Val Asp Gly Thr Arg Thr Asn Val Tyr Leu Asn 
65                  70                  75                  80  


Glu Val Gln Val Ala Asp Phe Ala Ser Phe Leu Glu Phe Val Tyr Thr 
                85                  90                  95      


Ala Lys Val Gln Val Glu Glu Asp Arg Val Gln Arg Met Leu Glu Val 
            100                 105                 110         


Ala Glu Lys Leu Lys Cys Leu Asp Leu Ser Glu Thr Cys Phe Gln Leu 
        115                 120                 125             


Lys Lys Gln Met Leu Glu Ser Val Leu Leu Glu Leu Gln Asn Phe Ser 
    130                 135                 140                 


Glu Ser Gln Glu Val Glu Val Ser Ser Gly Ser Gln Val Ser Ala Ala 
145                 150                 155                 160 


Pro Ala Pro Arg Ala Ser Val Ala Thr Asp Gly Pro His Pro Ser Gly 
                165                 170                 175     


Leu Thr Asp Ser Leu Asp Tyr Pro Gly Glu Arg Ala Ser Asn Gly Met 
            180                 185                 190         


Ser Ser Asp Leu Pro Pro Lys Lys Ser Lys Asp Lys Leu Asp Lys Lys 
        195                 200                 205             


Lys Glu Val Val Lys Pro Pro Tyr Pro Lys Ile Arg Arg Ala Ser Gly 
    210                 215                 220                 


Arg Leu Ala Gly Arg Lys Val Phe Val Glu Ile Pro Lys Lys Lys Tyr 
225                 230                 235                 240 


Thr Arg Arg Leu Arg Glu Gln Gln Lys Thr Ala Glu Gly Asp Val Gly 
                245                 250                 255     


Asp Tyr Arg Cys Pro Gln Asp Gln Ser Pro Asp Arg Val Gly Thr Glu 
            260                 265                 270         


Met Glu Gln Val Ser Lys Asn Glu Gly Cys Gln Ala Gly Ala Glu Leu 
        275                 280                 285             


Glu Glu Leu Ser Lys Lys Ala Gly Pro Glu Glu Glu Glu Glu Glu Glu 
    290                 295                 300                 


Glu Glu Asp Glu Glu Gly Glu Lys Lys Lys Ser Asn Phe Lys Cys Ser 
305                 310                 315                 320 


Ile Cys Glu Lys Ala Phe Leu Tyr Glu Lys Ser Phe Leu Lys His Ser 
                325                 330                 335     


Lys His Arg His Gly Val Ala Thr Glu Val Val Tyr Arg Cys Asp Thr 
            340                 345                 350         


Cys Gly Gln Thr Phe Ala Asn Arg Cys Asn Leu Lys Ser His Gln Arg 
        355                 360                 365             


His Val His Ser Ser Glu Arg His Phe Pro Cys Glu Leu Cys Gly Lys 
    370                 375                 380                 


Lys Phe Lys Arg Lys Lys Asp Val Lys Arg His Val Leu Gln Val His 
385                 390                 395                 400 


Glu Gly Gly Gly Glu Arg His Arg Cys Gly Gln Cys Gly Lys Gly Leu 
                405                 410                 415     


Ser Ser Lys Thr Ala Leu Arg Leu His Glu Arg Thr His Thr Gly Asp 
            420                 425                 430         


Arg Pro Tyr Gly Cys Thr Glu Cys Gly Ala Arg Phe Ser Gln Pro Ser 
        435                 440                 445             


Ala Leu Lys Thr His Met Arg Ile His Thr Gly Glu Lys Pro Phe Val 
    450                 455                 460                 


Cys Asp Glu Cys Gly Ala Arg Phe Thr Gln Asn His Met Leu Ile Tyr 
465                 470                 475                 480 


His Lys Arg Cys His Thr Gly Glu Arg Pro Phe Met Cys Glu Thr Cys 
                485                 490                 495     


Gly Lys Ser Phe Ala Ser Lys Glu Tyr Leu Lys His His Asn Arg Ile 
            500                 505                 510         


His Thr Gly Ser Lys Pro Phe Lys Cys Glu Val Cys Phe Arg Thr Phe 
        515                 520                 525             


Ala Gln Arg Asn Ser Leu Tyr Gln His Ile Lys Val His Thr Gly Glu 
    530                 535                 540                 


Arg Pro Tyr Cys Cys Asp Gln Cys Gly Lys Gln Phe Thr Gln Leu Asn 
545                 550                 555                 560 


Ala Leu Gln Arg His Arg Arg Ile His Thr Gly Glu Arg Pro Phe Met 
                565                 570                 575     


Cys Asn Ala Cys Gly Arg Thr Phe Thr Asp Lys Ser Thr Leu Arg Arg 
            580                 585                 590         


His Thr Ser Ile His Asp Lys Asn Thr Pro Trp Lys Ser Phe Leu Val 
        595                 600                 605             


Ile Val Asp Gly Ser Pro Lys Asn Asp Asp Gly His Lys Thr Glu Gln 
    610                 615                 620                 


Pro Asp Glu Glu Tyr Val Ser Ser Lys Leu Ser Asp Lys Leu Leu Ser 
625                 630                 635                 640 


Phe Ala Glu Asn Gly His Phe His Asn Leu Ala Ala Val Gln Asp Thr 
                645                 650                 655     


Val Pro Thr Met Gln Glu Asn Ser Ser Ala Asp Thr Ala Cys Lys Ala 
            660                 665                 670         


Asp Asp Ser Val Val Ser Gln Asp Thr Leu Leu Ala Thr Thr Ile Ser 
        675                 680                 685             


Glu Leu Ser Glu Leu Thr Pro Gln Thr Asp Ser Met Pro Thr Gln Leu 
    690                 695                 700                 


His Ser Leu Ser Asn Met Glu 
705                 710     


<210>  4129
<211>  580
<212>  PRT
<213>  homo sapiens

<400>  4129

Met Ala Gly Thr Val Arg Thr Ala Cys Leu Val Val Ala Met Leu Leu 
1               5                   10                  15      


Ser Leu Asp Phe Pro Gly Gln Ala Gln Pro Pro Pro Pro Pro Pro Asp 
            20                  25                  30          


Ala Thr Cys His Gln Val Arg Ser Phe Phe Gln Arg Leu Gln Pro Gly 
        35                  40                  45              


Leu Lys Trp Val Pro Glu Thr Pro Val Pro Gly Ser Asp Leu Gln Val 
    50                  55                  60                  


Cys Leu Pro Lys Gly Pro Thr Cys Cys Ser Arg Lys Met Glu Glu Lys 
65                  70                  75                  80  


Tyr Gln Leu Thr Ala Arg Leu Asn Met Glu Gln Leu Leu Gln Ser Ala 
                85                  90                  95      


Ser Met Glu Leu Lys Phe Leu Ile Ile Gln Asn Ala Ala Val Phe Gln 
            100                 105                 110         


Glu Ala Phe Glu Ile Val Val Arg His Ala Lys Asn Tyr Thr Asn Ala 
        115                 120                 125             


Met Phe Lys Asn Asn Tyr Pro Ser Leu Thr Pro Gln Ala Phe Glu Phe 
    130                 135                 140                 


Val Gly Glu Phe Phe Thr Asp Val Ser Leu Tyr Ile Leu Gly Ser Asp 
145                 150                 155                 160 


Ile Asn Val Asp Asp Met Val Asn Glu Leu Phe Asp Ser Leu Phe Pro 
                165                 170                 175     


Val Ile Tyr Thr Gln Leu Met Asn Pro Gly Leu Pro Asp Ser Ala Leu 
            180                 185                 190         


Asp Ile Asn Glu Cys Leu Arg Gly Ala Arg Arg Asp Leu Lys Val Phe 
        195                 200                 205             


Gly Asn Phe Pro Lys Leu Ile Met Thr Gln Val Ser Lys Ser Leu Gln 
    210                 215                 220                 


Val Thr Arg Ile Phe Leu Gln Ala Leu Asn Leu Gly Ile Glu Val Ile 
225                 230                 235                 240 


Asn Thr Thr Asp His Leu Lys Phe Ser Lys Asp Cys Gly Arg Met Leu 
                245                 250                 255     


Thr Arg Met Trp Tyr Cys Ser Tyr Cys Gln Gly Leu Met Met Val Lys 
            260                 265                 270         


Pro Cys Gly Gly Tyr Cys Asn Val Val Met Gln Gly Cys Met Ala Gly 
        275                 280                 285             


Val Val Glu Ile Asp Lys Tyr Trp Arg Glu Tyr Ile Leu Ser Leu Glu 
    290                 295                 300                 


Glu Leu Val Asn Gly Met Tyr Arg Ile Tyr Asp Met Glu Asn Val Leu 
305                 310                 315                 320 


Leu Gly Leu Phe Ser Thr Ile His Asp Ser Ile Gln Tyr Val Gln Lys 
                325                 330                 335     


Asn Ala Gly Lys Leu Thr Thr Thr Ile Gly Lys Leu Cys Ala His Ser 
            340                 345                 350         


Gln Gln Arg Gln Tyr Arg Ser Ala Tyr Tyr Pro Glu Asp Leu Phe Ile 
        355                 360                 365             


Asp Lys Lys Val Leu Lys Val Ala His Val Glu His Glu Glu Thr Leu 
    370                 375                 380                 


Ser Ser Arg Arg Arg Glu Leu Ile Gln Lys Leu Lys Ser Phe Ile Ser 
385                 390                 395                 400 


Phe Tyr Ser Ala Leu Pro Gly Tyr Ile Cys Ser His Ser Pro Val Ala 
                405                 410                 415     


Glu Asn Asp Thr Leu Cys Trp Asn Gly Gln Glu Leu Val Glu Arg Tyr 
            420                 425                 430         


Ser Gln Lys Ala Ala Arg Asn Gly Met Lys Asn Gln Phe Asn Leu His 
        435                 440                 445             


Glu Leu Lys Met Lys Gly Pro Glu Pro Val Val Ser Gln Ile Ile Asp 
    450                 455                 460                 


Lys Leu Lys His Ile Asn Gln Leu Leu Arg Thr Met Ser Met Pro Lys 
465                 470                 475                 480 


Gly Arg Val Leu Asp Lys Asn Leu Asp Glu Glu Gly Phe Glu Ser Gly 
                485                 490                 495     


Asp Cys Gly Asp Asp Glu Asp Glu Cys Ile Gly Gly Ser Gly Asp Gly 
            500                 505                 510         


Met Ile Lys Val Lys Asn Gln Leu Arg Phe Leu Ala Glu Leu Ala Tyr 
        515                 520                 525             


Asp Leu Asp Val Asp Asp Ala Pro Gly Asn Ser Gln Gln Ala Thr Pro 
    530                 535                 540                 


Lys Asp Asn Glu Ile Ser Thr Phe His Asn Leu Gly Asn Val His Ser 
545                 550                 555                 560 


Pro Leu Lys Leu Leu Thr Ser Met Ala Ile Ser Val Val Cys Phe Phe 
                565                 570                 575     


Phe Leu Val His 
            580 


<210>  4130
<211>  441
<212>  PRT
<213>  homo sapiens

<400>  4130

Met Lys Thr Leu Pro Leu His Ser His Cys Thr Glu Met Gln Arg Leu 
1               5                   10                  15      


Leu Pro Lys Leu Glu Met Leu Thr Leu Gly Ser Ser Phe Cys Ser Leu 
            20                  25                  30          


Gln Gly Glu Phe Cys Gln Ala Met Asp Ser Phe Thr Thr Val Ser His 
        35                  40                  45              


Val Gly Met Cys Glu Glu Thr Asp Ala Ser Phe Asn Val Phe Ser Pro 
    50                  55                  60                  


Lys Phe Gln Phe Asp Arg Ser His Cys Gln Ser Leu Arg Phe His Gln 
65                  70                  75                  80  


Asn Met Glu Leu Asp Phe Gly His Phe Asp Glu Arg Asp Lys Thr Ser 
                85                  90                  95      


Arg Asn Met Arg Gly Ser Arg Met Asn Gly Leu Pro Ser Pro Thr His 
            100                 105                 110         


Ser Ala His Cys Ser Phe Tyr Arg Thr Arg Thr Leu Gln Ala Leu Ser 
        115                 120                 125             


Asn Glu Lys Lys Ala Lys Lys Val Arg Phe Tyr Arg Asn Gly Asp Arg 
    130                 135                 140                 


Tyr Phe Lys Gly Ile Val Tyr Ala Val Ser Ser Asp Arg Phe Arg Ser 
145                 150                 155                 160 


Phe Asp Ala Leu Leu Ala Asp Leu Thr Arg Ser Leu Ser Asp Asn Ile 
                165                 170                 175     


Asn Leu Pro Gln Gly Val Arg Tyr Ile Tyr Thr Ile Asp Gly Ser Arg 
            180                 185                 190         


Lys Ile Gly Ser Met Asp Glu Leu Glu Glu Gly Glu Ser Tyr Val Cys 
        195                 200                 205             


Ser Ser Asp Asn Phe Phe Lys Lys Val Glu Tyr Thr Lys Asn Val Asn 
    210                 215                 220                 


Pro Asn Trp Ser Val Asn Val Lys Thr Ser Ala Asn Met Lys Ala Pro 
225                 230                 235                 240 


Gln Ser Leu Ala Ser Ser Asn Ser Ala Gln Ala Arg Glu Asn Lys Asp 
                245                 250                 255     


Phe Val Arg Pro Lys Leu Val Thr Ile Ile Arg Ser Gly Val Lys Pro 
            260                 265                 270         


Arg Lys Ala Val Arg Val Leu Leu Asn Lys Lys Thr Ala His Ser Phe 
        275                 280                 285             


Glu Gln Val Leu Thr Asp Ile Thr Glu Ala Ile Lys Leu Glu Thr Gly 
    290                 295                 300                 


Val Val Lys Lys Leu Tyr Thr Leu Asp Gly Lys Gln Val Thr Cys Leu 
305                 310                 315                 320 


His Asp Phe Phe Gly Asp Asp Asp Val Phe Ile Ala Cys Gly Pro Glu 
                325                 330                 335     


Lys Phe Arg Tyr Ala Gln Asp Asp Phe Ser Leu Asp Glu Asn Glu Cys 
            340                 345                 350         


Arg Val Met Lys Gly Asn Pro Ser Ala Thr Ala Gly Pro Lys Ala Ser 
        355                 360                 365             


Pro Thr Pro Gln Lys Thr Ser Ala Lys Ser Pro Gly Pro Met Arg Arg 
    370                 375                 380                 


Ser Lys Ser Pro Ala Asp Ser Ala Asn Gly Thr Ser Ser Ser Gln Leu 
385                 390                 395                 400 


Ser Thr Pro Lys Ser Lys Gln Ser Pro Ile Ser Thr Pro Thr Ser Pro 
                405                 410                 415     


Gly Ser Leu Arg Lys His Lys Asp Leu Tyr Leu Pro Leu Ser Leu Asp 
            420                 425                 430         


Asp Ser Asp Ser Leu Gly Asp Ser Met 
        435                 440     


<210>  4131
<211>  875
<212>  PRT
<213>  homo sapiens

<400>  4131

Met Asp Glu Glu Glu Asp Asn Leu Ser Leu Leu Thr Ala Leu Leu Glu 
1               5                   10                  15      


Glu Asn Glu Ser Ala Leu Asp Cys Asn Ser Glu Glu Asn Asn Phe Leu 
            20                  25                  30          


Thr Arg Glu Asn Gly Glu Pro Asp Ala Phe Asp Glu Leu Phe Asp Ala 
        35                  40                  45              


Asp Gly Asp Gly Glu Ser Tyr Thr Glu Glu Ala Asp Asp Gly Glu Thr 
    50                  55                  60                  


Gly Glu Thr Arg Asp Glu Lys Glu Asn Leu Ala Thr Leu Phe Gly Asp 
65                  70                  75                  80  


Met Glu Asp Leu Thr Asp Glu Glu Glu Val Pro Ala Ser Gln Ser Thr 
                85                  90                  95      


Glu Asn Arg Val Leu Pro Ala Pro Ala Pro Arg Arg Glu Lys Thr Asn 
            100                 105                 110         


Glu Glu Leu Gln Glu Glu Leu Arg Asn Leu Gln Glu Gln Met Lys Ala 
        115                 120                 125             


Leu Gln Glu Gln Leu Lys Val Thr Thr Ile Lys Gln Thr Ala Ser Pro 
    130                 135                 140                 


Ala Arg Leu Gln Lys Ser Pro Val Glu Lys Ser Pro Arg Pro Pro Leu 
145                 150                 155                 160 


Lys Glu Arg Arg Val Gln Arg Ile Gln Glu Ser Thr Cys Phe Ser Ala 
                165                 170                 175     


Glu Leu Asp Val Pro Ala Leu Pro Arg Thr Lys Arg Val Ala Arg Thr 
            180                 185                 190         


Pro Lys Ala Ser Pro Pro Asp Pro Lys Ser Ser Ser Ser Arg Met Thr 
        195                 200                 205             


Ser Ala Pro Ser Gln Pro Leu Gln Thr Ile Ser Arg Asn Lys Pro Ser 
    210                 215                 220                 


Gly Ile Thr Arg Gly Gln Ile Val Gly Thr Pro Gly Ser Ser Gly Glu 
225                 230                 235                 240 


Thr Thr Gln Pro Ile Cys Val Glu Ala Phe Ser Gly Leu Arg Leu Arg 
                245                 250                 255     


Arg Pro Arg Val Ser Ser Thr Glu Met Asn Lys Lys Met Thr Gly Arg 
            260                 265                 270         


Lys Leu Ile Arg Leu Ser Gln Ile Lys Glu Lys Met Ala Arg Glu Lys 
        275                 280                 285             


Leu Glu Glu Ile Asp Trp Val Thr Phe Gly Val Ile Leu Lys Lys Val 
    290                 295                 300                 


Thr Pro Gln Ser Val Asn Ser Gly Lys Thr Phe Ser Ile Trp Lys Leu 
305                 310                 315                 320 


Asn Asp Leu Arg Asp Leu Thr Gln Cys Val Ser Leu Phe Leu Phe Gly 
                325                 330                 335     


Glu Val His Lys Ala Leu Trp Lys Thr Glu Gln Gly Thr Val Val Gly 
            340                 345                 350         


Ile Leu Asn Ala Asn Pro Met Lys Pro Lys Asp Gly Ser Glu Glu Val 
        355                 360                 365             


Cys Leu Ser Ile Asp His Pro Gln Lys Val Leu Ile Met Gly Glu Ala 
    370                 375                 380                 


Leu Asp Leu Gly Thr Cys Lys Ala Lys Lys Lys Asn Gly Glu Pro Cys 
385                 390                 395                 400 


Thr Gln Thr Val Asn Leu Arg Asp Cys Glu Tyr Cys Gln Tyr His Val 
                405                 410                 415     


Gln Ala Gln Tyr Lys Lys Leu Ser Ala Lys Arg Ala Asp Leu Gln Ser 
            420                 425                 430         


Thr Phe Ser Gly Gly Arg Ile Pro Lys Lys Phe Ala Arg Arg Gly Thr 
        435                 440                 445             


Ser Leu Lys Glu Arg Leu Cys Gln Asp Gly Phe Tyr Tyr Gly Gly Val 
    450                 455                 460                 


Ser Ser Ala Ser Tyr Ala Ala Ser Ile Ala Ala Ala Val Ala Pro Lys 
465                 470                 475                 480 


Lys Lys Ile Gln Thr Thr Leu Ser Asn Leu Val Val Lys Gly Thr Asn 
                485                 490                 495     


Leu Ile Ile Gln Glu Thr Arg Gln Lys Leu Gly Ile Pro Gln Lys Ser 
            500                 505                 510         


Leu Ser Cys Ser Glu Glu Phe Lys Glu Leu Met Asp Leu Pro Thr Cys 
        515                 520                 525             


Gly Ala Arg Asn Leu Lys Gln His Leu Ala Lys Ala Thr Ala Ser Gly 
    530                 535                 540                 


Ile Met Gly Ser Pro Lys Pro Ala Ile Lys Ser Ile Ser Ala Ser Ala 
545                 550                 555                 560 


Leu Leu Lys Gln Gln Lys Gln Arg Met Leu Glu Met Arg Arg Arg Lys 
                565                 570                 575     


Ser Glu Glu Ile Gln Lys Arg Phe Leu Gln Ser Ser Ser Glu Val Glu 
            580                 585                 590         


Ser Pro Ala Val Pro Ser Ser Ser Arg Gln Pro Pro Ala Gln Pro Pro 
        595                 600                 605             


Arg Thr Gly Ser Glu Phe Pro Arg Leu Glu Gly Ala Pro Ala Thr Met 
    610                 615                 620                 


Thr Pro Lys Leu Gly Arg Gly Val Leu Glu Gly Asp Asp Val Leu Phe 
625                 630                 635                 640 


Tyr Asp Glu Ser Pro Pro Pro Arg Pro Lys Leu Ser Ala Leu Ala Glu 
                645                 650                 655     


Ala Lys Lys Leu Ala Ala Ile Thr Lys Leu Arg Ala Lys Gly Gln Val 
            660                 665                 670         


Leu Thr Lys Thr Asn Pro Asn Ser Ile Lys Lys Lys Gln Lys Asp Pro 
        675                 680                 685             


Gln Asp Ile Leu Glu Val Lys Glu Arg Val Glu Lys Asn Thr Met Phe 
    690                 695                 700                 


Ser Ser Gln Ala Glu Asp Glu Leu Glu Pro Ala Arg Lys Lys Arg Arg 
705                 710                 715                 720 


Glu Gln Leu Ala Tyr Leu Glu Ser Glu Glu Phe Gln Lys Ile Leu Lys 
                725                 730                 735     


Ala Lys Ser Lys His Thr Gly Ile Leu Lys Glu Ala Glu Ala Glu Met 
            740                 745                 750         


Gln Glu Arg Tyr Phe Glu Pro Leu Val Lys Lys Glu Gln Met Glu Glu 
        755                 760                 765             


Lys Met Arg Asn Ile Arg Glu Val Lys Cys Arg Val Val Thr Cys Lys 
    770                 775                 780                 


Thr Cys Ala Tyr Thr His Phe Lys Leu Leu Glu Thr Cys Val Ser Glu 
785                 790                 795                 800 


Gln His Glu Tyr His Trp His Asp Gly Val Lys Arg Phe Phe Lys Cys 
                805                 810                 815     


Pro Cys Gly Asn Arg Ser Ile Ser Leu Asp Arg Leu Pro Asn Lys His 
            820                 825                 830         


Cys Ser Asn Cys Gly Leu Tyr Lys Trp Glu Arg Asp Gly Met Leu Lys 
        835                 840                 845             


Glu Lys Thr Gly Pro Lys Ile Gly Gly Glu Thr Leu Leu Pro Arg Gly 
    850                 855                 860                 


Glu Glu His Ala Lys Phe Leu Asn Ser Leu Lys 
865                 870                 875 


<210>  4132
<211>  863
<212>  PRT
<213>  homo sapiens

<400>  4132

Met Ser Ser Pro Ala Ser Thr Pro Ser Arg Arg Gly Ser Arg Arg Gly 
1               5                   10                  15      


Arg Ala Thr Pro Ala Gln Thr Pro Arg Ser Glu Asp Ala Arg Ser Ser 
            20                  25                  30          


Pro Ser Gln Arg Arg Arg Gly Glu Asp Ser Thr Ser Thr Gly Glu Leu 
        35                  40                  45              


Gln Pro Met Pro Thr Ser Pro Gly Val Asp Leu Gln Ser Pro Ala Ala 
    50                  55                  60                  


Gln Asp Val Leu Phe Ser Ser Pro Pro Gln Met His Ser Ser Ala Ile 
65                  70                  75                  80  


Pro Leu Asp Phe Asp Val Ser Ser Pro Leu Thr Tyr Gly Thr Pro Ser 
                85                  90                  95      


Ser Arg Val Glu Gly Thr Pro Arg Ser Gly Val Arg Gly Thr Pro Val 
            100                 105                 110         


Arg Gln Arg Pro Asp Leu Gly Ser Ala Gln Lys Gly Leu Gln Val Asp 
        115                 120                 125             


Leu Gln Ser Asp Gly Ala Ala Ala Glu Asp Ile Val Ala Ser Glu Gln 
    130                 135                 140                 


Ser Leu Gly Gln Lys Leu Val Ile Trp Gly Thr Asp Val Asn Val Ala 
145                 150                 155                 160 


Ala Cys Lys Glu Asn Phe Gln Arg Phe Leu Gln Arg Phe Ile Asp Pro 
                165                 170                 175     


Leu Ala Lys Glu Glu Glu Asn Val Gly Ile Asp Ile Thr Glu Pro Leu 
            180                 185                 190         


Tyr Met Gln Arg Leu Gly Glu Ile Asn Val Ile Gly Glu Pro Phe Leu 
        195                 200                 205             


Asn Val Asn Cys Glu His Ile Lys Ser Phe Asp Lys Asn Leu Tyr Arg 
    210                 215                 220                 


Gln Leu Ile Ser Tyr Pro Gln Glu Val Ile Pro Thr Phe Asp Met Ala 
225                 230                 235                 240 


Val Asn Glu Ile Phe Phe Asp Arg Tyr Pro Asp Ser Ile Leu Glu His 
                245                 250                 255     


Gln Ile Gln Val Arg Pro Phe Asn Ala Leu Lys Thr Lys Asn Met Arg 
            260                 265                 270         


Asn Leu Asn Pro Glu Asp Ile Asp Gln Leu Ile Thr Ile Ser Gly Met 
        275                 280                 285             


Val Ile Arg Thr Ser Gln Leu Ile Pro Glu Met Gln Glu Ala Phe Phe 
    290                 295                 300                 


Gln Cys Gln Val Cys Ala His Thr Thr Arg Val Glu Met Asp Arg Gly 
305                 310                 315                 320 


Arg Ile Ala Glu Pro Ser Val Cys Gly Arg Cys His Thr Thr His Ser 
                325                 330                 335     


Met Ala Leu Ile His Asn Arg Ser Leu Phe Ser Asp Lys Gln Met Ile 
            340                 345                 350         


Lys Leu Gln Glu Ser Pro Glu Asp Met Pro Ala Gly Gln Thr Pro His 
        355                 360                 365             


Thr Val Ile Leu Phe Ala His Asn Asp Leu Val Asp Lys Val Gln Pro 
    370                 375                 380                 


Gly Asp Arg Val Asn Val Thr Gly Ile Tyr Arg Ala Val Pro Ile Arg 
385                 390                 395                 400 


Val Asn Pro Arg Val Ser Asn Val Lys Ser Val Tyr Lys Thr His Ile 
                405                 410                 415     


Asp Val Ile His Tyr Arg Lys Thr Asp Ala Lys Arg Leu His Gly Leu 
            420                 425                 430         


Asp Glu Glu Ala Glu Gln Lys Leu Phe Ser Glu Lys Arg Val Glu Leu 
        435                 440                 445             


Leu Lys Glu Leu Ser Arg Lys Pro Asp Ile Tyr Glu Arg Leu Ala Ser 
    450                 455                 460                 


Ala Leu Ala Pro Ser Ile Tyr Glu His Glu Asp Ile Lys Lys Gly Ile 
465                 470                 475                 480 


Leu Leu Gln Leu Phe Gly Gly Thr Arg Lys Asp Phe Ser His Thr Gly 
                485                 490                 495     


Arg Gly Lys Phe Arg Ala Glu Ile Asn Ile Leu Leu Cys Gly Asp Pro 
            500                 505                 510         


Gly Thr Ser Lys Ser Gln Leu Leu Gln Tyr Val Tyr Asn Leu Val Pro 
        515                 520                 525             


Arg Gly Gln Tyr Thr Ser Gly Lys Gly Ser Ser Ala Val Gly Leu Thr 
    530                 535                 540                 


Ala Tyr Val Met Lys Asp Pro Glu Thr Arg Gln Leu Val Leu Gln Thr 
545                 550                 555                 560 


Gly Ala Leu Val Leu Ser Asp Asn Gly Ile Cys Cys Ile Asp Glu Phe 
                565                 570                 575     


Asp Lys Met Asn Glu Ser Thr Arg Ser Val Leu His Glu Val Met Glu 
            580                 585                 590         


Gln Gln Thr Leu Ser Ile Ala Lys Ala Gly Ile Ile Cys Gln Leu Asn 
        595                 600                 605             


Ala Arg Thr Ser Val Leu Ala Ala Ala Asn Pro Ile Glu Ser Gln Trp 
    610                 615                 620                 


Asn Pro Lys Lys Thr Thr Ile Glu Asn Ile Gln Leu Pro His Thr Leu 
625                 630                 635                 640 


Leu Ser Arg Phe Asp Leu Ile Phe Leu Leu Leu Asp Pro Gln Asp Glu 
                645                 650                 655     


Ala Tyr Asp Arg Arg Leu Ala His His Leu Val Ala Leu Tyr Tyr Gln 
            660                 665                 670         


Ser Glu Glu Gln Ala Glu Glu Glu Leu Leu Asp Met Ala Val Leu Lys 
        675                 680                 685             


Asp Tyr Ile Ala Tyr Ala His Ser Thr Ile Met Pro Arg Leu Ser Glu 
    690                 695                 700                 


Glu Ala Ser Gln Ala Leu Ile Glu Ala Tyr Val Asp Met Arg Lys Ile 
705                 710                 715                 720 


Gly Ser Ser Arg Gly Met Val Ser Ala Tyr Pro Arg Gln Leu Glu Ser 
                725                 730                 735     


Leu Ile Arg Leu Ala Glu Ala His Ala Lys Val Arg Leu Ser Asn Lys 
            740                 745                 750         


Val Glu Ala Ile Asp Val Glu Glu Ala Lys Arg Leu His Arg Glu Ala 
        755                 760                 765             


Leu Lys Gln Ser Ala Thr Asp Pro Arg Thr Gly Ile Val Asp Ile Ser 
    770                 775                 780                 


Ile Leu Thr Thr Gly Met Ser Ala Thr Ser Arg Lys Arg Lys Glu Glu 
785                 790                 795                 800 


Leu Ala Glu Ala Leu Lys Lys Leu Ile Leu Ser Lys Gly Lys Thr Pro 
                805                 810                 815     


Ala Leu Lys Tyr Gln Gln Leu Phe Glu Asp Ile Arg Gly Gln Ser Asp 
            820                 825                 830         


Ile Ala Ile Thr Lys Asp Met Phe Glu Glu Ala Leu Arg Ala Leu Ala 
        835                 840                 845             


Asp Asp Asp Phe Leu Thr Val Thr Gly Lys Thr Val Arg Leu Leu 
    850                 855                 860             


<210>  4133
<211>  277
<212>  PRT
<213>  homo sapiens

<400>  4133

Met Glu Ala Ala Glu Thr Glu Ala Glu Ala Ala Ala Leu Glu Val Leu 
1               5                   10                  15      


Ala Glu Val Ala Gly Ile Leu Glu Pro Val Gly Leu Gln Glu Glu Ala 
            20                  25                  30          


Glu Leu Pro Ala Lys Ile Leu Val Glu Phe Val Val Asp Ser Gln Lys 
        35                  40                  45              


Lys Asp Lys Leu Leu Cys Ser Gln Leu Gln Val Ala Asp Phe Leu Gln 
    50                  55                  60                  


Asn Ile Leu Ala Gln Glu Asp Thr Ala Lys Gly Leu Asp Pro Leu Ala 
65                  70                  75                  80  


Ser Glu Asp Thr Ser Arg Gln Lys Ala Ile Ala Ala Lys Glu Gln Trp 
                85                  90                  95      


Lys Glu Leu Lys Ala Thr Tyr Arg Glu His Val Glu Ala Ile Lys Ile 
            100                 105                 110         


Gly Leu Thr Lys Ala Leu Thr Gln Met Glu Glu Ala Gln Arg Lys Arg 
        115                 120                 125             


Thr Gln Leu Arg Glu Ala Phe Glu Gln Leu Gln Ala Lys Lys Gln Met 
    130                 135                 140                 


Ala Met Glu Lys Arg Arg Ala Val Gln Asn Gln Trp Gln Leu Gln Gln 
145                 150                 155                 160 


Glu Lys His Leu Gln His Leu Ala Glu Val Ser Ala Glu Val Arg Glu 
                165                 170                 175     


Arg Lys Thr Gly Thr Gln Gln Glu Leu Asp Arg Val Phe Gln Lys Leu 
            180                 185                 190         


Gly Asn Leu Lys Gln Gln Ala Glu Gln Glu Arg Asp Lys Leu Gln Arg 
        195                 200                 205             


Tyr Gln Thr Phe Leu Gln Leu Leu Tyr Thr Leu Gln Gly Lys Leu Leu 
    210                 215                 220                 


Phe Pro Glu Ala Glu Ala Glu Ala Glu Asn Leu Pro Asp Asp Lys Pro 
225                 230                 235                 240 


Gln Gln Pro Thr Arg Pro Gln Glu Gln Ser Thr Gly Asp Thr Met Gly 
                245                 250                 255     


Arg Asp Pro Gly Val Ser Phe Lys Ala Val Gly Leu Gln Pro Ala Gly 
            260                 265                 270         


Asp Val Asn Leu Pro 
        275         


<210>  4134
<211>  145
<212>  PRT
<213>  homo sapiens

<400>  4134

Met Gly Cys Gly Gly Ser Arg Ala Asp Ala Ile Glu Pro Arg Tyr Tyr 
1               5                   10                  15      


Glu Ser Trp Thr Arg Glu Thr Glu Ser Thr Trp Leu Thr Tyr Thr Asp 
            20                  25                  30          


Ser Asp Ala Pro Pro Ser Ala Ala Ala Pro Asp Ser Gly Pro Glu Ala 
        35                  40                  45              


Gly Gly Leu His Ser Gly Met Leu Glu Asp Gly Leu Pro Ser Asn Gly 
    50                  55                  60                  


Val Pro Arg Ser Thr Ala Pro Gly Gly Ile Pro Asn Pro Glu Lys Lys 
65                  70                  75                  80  


Thr Asn Cys Glu Thr Gln Cys Pro Asn Pro Gln Ser Leu Ser Ser Gly 
                85                  90                  95      


Pro Leu Thr Gln Lys Gln Asn Gly Leu Gln Thr Thr Glu Ala Lys Arg 
            100                 105                 110         


Asp Ala Lys Arg Met Pro Ala Lys Glu Val Thr Ile Asn Val Thr Asp 
        115                 120                 125             


Ser Ile Gln Gln Met Asp Arg Ser Arg Arg Ile Thr Lys Asn Cys Val 
    130                 135                 140                 


Asn 
145 


<210>  4135
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  4135

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Met Gln Asp Leu 
1               5                   10                  15      


Leu Glu Ser Thr Asp Phe Thr Glu His Glu Ile Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Arg Asp Cys Pro Ser Gly His Leu Ser Met Glu Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Gly Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Ala Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Lys Ala Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Glu Lys Ile Phe Arg Gln Met Asp Thr Asn Arg 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Gly Gln 
            180                 185                 190         


Phe 
    


<210>  4136
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  4136

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Met Gln Asp Leu 
1               5                   10                  15      


Leu Glu Ser Thr Asp Phe Thr Glu His Glu Ile Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Arg Asp Cys Pro Ser Gly His Leu Ser Met Glu Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Gly Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Ala Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Lys Ala Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Glu Lys Ile Phe Arg Gln Met Asp Thr Asn Arg 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Gly Gln 
            180                 185                 190         


Phe 
    


<210>  4137
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  4137

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Met Gln Asp Leu 
1               5                   10                  15      


Leu Glu Ser Thr Asp Phe Thr Glu His Glu Ile Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Arg Asp Cys Pro Ser Gly His Leu Ser Met Glu Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Gly Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Ala Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Lys Ala Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Glu Lys Ile Phe Arg Gln Met Asp Thr Asn Arg 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Gly Gln 
            180                 185                 190         


Phe 
    


<210>  4138
<211>  208
<212>  PRT
<213>  homo sapiens

<400>  4138

Met Ser Thr Gly Gly Asp Phe Gly Asn Pro Leu Arg Lys Phe Lys Leu 
1               5                   10                  15      


Val Phe Leu Gly Glu Gln Ser Val Gly Lys Thr Ser Leu Ile Thr Arg 
            20                  25                  30          


Phe Met Tyr Asp Ser Phe Asp Asn Thr Tyr Gln Ala Thr Ile Gly Ile 
        35                  40                  45              


Asp Phe Leu Ser Lys Thr Met Tyr Leu Glu Asp Arg Thr Val Arg Leu 
    50                  55                  60                  


Gln Leu Trp Asp Thr Ala Gly Gln Glu Arg Phe Arg Ser Leu Ile Pro 
65                  70                  75                  80  


Ser Tyr Ile Arg Asp Ser Thr Val Ala Val Val Val Tyr Asp Ile Thr 
                85                  90                  95      


Asn Val Asn Ser Phe Gln Gln Thr Thr Lys Trp Ile Asp Asp Val Arg 
            100                 105                 110         


Thr Glu Arg Gly Ser Asp Val Ile Ile Met Leu Val Gly Asn Lys Thr 
        115                 120                 125             


Asp Leu Ala Asp Lys Arg Gln Val Ser Ile Glu Glu Gly Glu Arg Lys 
    130                 135                 140                 


Ala Lys Glu Leu Asn Val Met Phe Ile Glu Thr Ser Ala Lys Ala Gly 
145                 150                 155                 160 


Tyr Asn Val Lys Gln Leu Phe Arg Arg Val Ala Ala Ala Leu Pro Gly 
                165                 170                 175     


Met Glu Ser Thr Gln Asp Arg Ser Arg Glu Asp Met Ile Asp Ile Lys 
            180                 185                 190         


Leu Glu Lys Pro Gln Glu Gln Pro Val Ser Glu Gly Gly Cys Ser Cys 
        195                 200                 205             


<210>  4139
<211>  305
<212>  PRT
<213>  homo sapiens

<400>  4139

Met Glu Arg Leu Val Ala Arg Gly Thr Phe Pro Val Leu Val Arg Thr 
1               5                   10                  15      


Ser Ala Cys Arg Ser Leu Phe Gly Pro Val Asp His Glu Glu Leu Ser 
            20                  25                  30          


Arg Glu Leu Gln Ala Arg Leu Ala Glu Leu Asn Ala Glu Asp Gln Asn 
        35                  40                  45              


Arg Trp Asp Tyr Asp Phe Gln Gln Asp Met Pro Leu Arg Gly Pro Gly 
    50                  55                  60                  


Arg Leu Gln Trp Thr Glu Val Asp Ser Asp Ser Val Pro Ala Phe Tyr 
65                  70                  75                  80  


Arg Glu Thr Val Gln Val Gly Arg Cys Arg Leu Leu Leu Ala Pro Arg 
                85                  90                  95      


Pro Val Ala Val Ala Val Ala Val Ser Pro Pro Leu Glu Pro Ala Ala 
            100                 105                 110         


Glu Ser Leu Asp Gly Leu Glu Glu Ala Pro Glu Gln Leu Pro Ser Val 
        115                 120                 125             


Pro Val Pro Ala Pro Ala Ser Thr Pro Pro Pro Val Pro Val Leu Ala 
    130                 135                 140                 


Pro Ala Pro Ala Pro Ala Pro Ala Pro Val Ala Ala Pro Val Ala Ala 
145                 150                 155                 160 


Pro Val Ala Val Ala Val Leu Ala Pro Ala Pro Ala Pro Ala Pro Ala 
                165                 170                 175     


Pro Ala Pro Ala Pro Ala Pro Val Ala Ala Pro Ala Pro Ala Pro Ala 
            180                 185                 190         


Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Asp Ala Ala 
        195                 200                 205             


Pro Gln Glu Ser Ala Glu Gln Gly Ala Asn Gln Gly Gln Arg Gly Gln 
    210                 215                 220                 


Glu Pro Leu Ala Asp Gln Leu His Ser Gly Ile Ser Gly Arg Pro Ala 
225                 230                 235                 240 


Ala Gly Thr Ala Ala Ala Ser Ala Asn Gly Ala Ala Ile Lys Lys Leu 
                245                 250                 255     


Ser Gly Pro Leu Ile Ser Asp Phe Phe Ala Lys Arg Lys Arg Ser Ala 
            260                 265                 270         


Pro Glu Lys Ser Ser Gly Asp Val Pro Ala Pro Cys Pro Ser Pro Ser 
        275                 280                 285             


Ala Ala Pro Gly Val Gly Ser Val Glu Gln Thr Pro Arg Lys Arg Leu 
    290                 295                 300                 


Arg 
305 


<210>  4140
<211>  333
<212>  PRT
<213>  homo sapiens

<400>  4140

Met Pro Leu Gly Leu Gly Arg Arg Lys Lys Ala Pro Pro Leu Val Glu 
1               5                   10                  15      


Asn Glu Glu Ala Glu Pro Gly Arg Gly Gly Leu Gly Val Gly Glu Pro 
            20                  25                  30          


Gly Pro Leu Gly Gly Gly Gly Ser Gly Gly Pro Gln Met Gly Leu Pro 
        35                  40                  45              


Pro Pro Pro Pro Ala Leu Arg Pro Arg Leu Val Phe His Thr Gln Leu 
    50                  55                  60                  


Ala His Gly Ser Pro Thr Gly Arg Ile Glu Gly Phe Thr Asn Val Lys 
65                  70                  75                  80  


Glu Leu Tyr Gly Lys Ile Ala Glu Ala Phe Arg Leu Pro Thr Ala Glu 
                85                  90                  95      


Val Met Phe Cys Thr Leu Asn Thr His Lys Val Asp Met Asp Lys Leu 
            100                 105                 110         


Leu Gly Gly Gln Ile Gly Leu Glu Asp Phe Ile Phe Ala His Val Lys 
        115                 120                 125             


Gly Gln Arg Lys Glu Val Glu Val Phe Lys Ser Glu Asp Ala Leu Gly 
    130                 135                 140                 


Leu Thr Ile Thr Asp Asn Gly Ala Gly Tyr Ala Phe Ile Lys Arg Ile 
145                 150                 155                 160 


Lys Glu Gly Ser Val Ile Asp His Ile His Leu Ile Ser Val Gly Asp 
                165                 170                 175     


Met Ile Glu Ala Ile Asn Gly Gln Ser Leu Leu Gly Cys Arg His Tyr 
            180                 185                 190         


Glu Val Ala Arg Leu Leu Lys Glu Leu Pro Arg Gly Arg Thr Phe Thr 
        195                 200                 205             


Leu Lys Leu Thr Glu Pro Arg Lys Ala Phe Asp Met Ile Ser Gln Arg 
    210                 215                 220                 


Ser Ala Gly Gly Arg Pro Gly Ser Gly Pro Gln Leu Gly Thr Gly Arg 
225                 230                 235                 240 


Gly Thr Leu Arg Leu Arg Ser Arg Gly Pro Ala Thr Val Glu Asp Leu 
                245                 250                 255     


Pro Ser Ala Phe Glu Glu Lys Ala Ile Glu Lys Val Asp Asp Leu Leu 
            260                 265                 270         


Glu Ser Tyr Met Gly Ile Arg Asp Thr Glu Leu Ala Ala Thr Met Val 
        275                 280                 285             


Glu Leu Gly Lys Asp Lys Arg Asn Pro Asp Glu Leu Ala Glu Ala Leu 
    290                 295                 300                 


Asp Glu Arg Leu Gly Asp Phe Ala Phe Pro Asp Glu Phe Val Phe Asp 
305                 310                 315                 320 


Val Trp Gly Ala Ile Gly Asp Ala Lys Val Gly Arg Tyr 
                325                 330             


<210>  4141
<211>  54
<212>  PRT
<213>  homo sapiens

<400>  4141

Met Gly Cys Gly Gly Ser Arg Ala Asp Ala Ile Glu Pro Arg Tyr Tyr 
1               5                   10                  15      


Glu Ser Trp Thr Arg Glu Thr Glu Ser Thr Trp Leu Thr Tyr Thr Asp 
            20                  25                  30          


Ser Asp Ala Pro Pro Ser Ala Ala Ala Pro Asp Ser Gly Pro Glu Ala 
        35                  40                  45              


Gly Gly Leu His Ser Gly 
    50                  


<210>  4142
<211>  1051
<212>  PRT
<213>  homo sapiens

<400>  4142

Met Lys Ser Glu Asp Tyr Pro His Glu Thr Met Ala Pro Asp Ile His 
1               5                   10                  15      


Glu Glu Arg Gln Tyr Arg Cys Glu Asp Cys Asp Gln Leu Phe Glu Ser 
            20                  25                  30          


Lys Ala Glu Leu Ala Asp His Gln Lys Phe Pro Cys Ser Thr Pro His 
        35                  40                  45              


Ser Ala Phe Ser Met Val Glu Glu Asp Phe Gln Gln Lys Leu Glu Ser 
    50                  55                  60                  


Glu Asn Asp Leu Gln Glu Ile His Thr Ile Gln Glu Cys Lys Glu Cys 
65                  70                  75                  80  


Asp Gln Val Phe Pro Asp Leu Gln Ser Leu Glu Lys His Met Leu Ser 
                85                  90                  95      


His Thr Glu Glu Arg Glu Tyr Lys Cys Asp Gln Cys Pro Lys Ala Phe 
            100                 105                 110         


Asn Trp Lys Ser Asn Leu Ile Arg His Gln Met Ser His Asp Ser Gly 
        115                 120                 125             


Lys His Tyr Glu Cys Glu Asn Cys Ala Lys Val Phe Thr Asp Pro Ser 
    130                 135                 140                 


Asn Leu Gln Arg His Ile Arg Ser Gln His Val Gly Ala Arg Ala His 
145                 150                 155                 160 


Ala Cys Pro Glu Cys Gly Lys Thr Phe Ala Thr Ser Ser Gly Leu Lys 
                165                 170                 175     


Gln His Lys His Ile His Ser Ser Val Lys Pro Phe Ile Cys Glu Val 
            180                 185                 190         


Cys His Lys Ser Tyr Thr Gln Phe Ser Asn Leu Cys Arg His Lys Arg 
        195                 200                 205             


Met His Ala Asp Cys Arg Thr Gln Ile Lys Cys Lys Asp Cys Gly Gln 
    210                 215                 220                 


Met Phe Ser Thr Thr Ser Ser Leu Asn Lys His Arg Arg Phe Cys Glu 
225                 230                 235                 240 


Gly Lys Asn His Phe Ala Ala Gly Gly Phe Phe Gly Gln Gly Ile Ser 
                245                 250                 255     


Leu Pro Gly Thr Pro Ala Met Asp Lys Thr Ser Met Val Asn Met Ser 
            260                 265                 270         


His Ala Asn Pro Gly Leu Ala Asp Tyr Phe Gly Ala Asn Arg His Pro 
        275                 280                 285             


Ala Gly Leu Thr Phe Pro Thr Ala Pro Gly Phe Ser Phe Ser Phe Pro 
    290                 295                 300                 


Gly Leu Phe Pro Ser Gly Leu Tyr His Arg Pro Pro Leu Ile Pro Ala 
305                 310                 315                 320 


Ser Ser Pro Val Lys Gly Leu Ser Ser Thr Glu Gln Thr Asn Lys Ser 
                325                 330                 335     


Gln Ser Pro Leu Met Thr His Pro Gln Ile Leu Pro Ala Thr Gln Asp 
            340                 345                 350         


Ile Leu Lys Ala Leu Ser Lys His Pro Ser Val Gly Asp Asn Lys Pro 
        355                 360                 365             


Val Glu Leu Gln Pro Glu Arg Ser Ser Glu Glu Arg Pro Phe Glu Lys 
    370                 375                 380                 


Ile Ser Asp Gln Ser Glu Ser Ser Asp Leu Asp Asp Val Ser Thr Pro 
385                 390                 395                 400 


Ser Gly Ser Asp Leu Glu Thr Thr Ser Gly Ser Asp Leu Glu Ser Asp 
                405                 410                 415     


Ile Glu Ser Asp Lys Glu Lys Phe Lys Glu Asn Gly Lys Met Phe Lys 
            420                 425                 430         


Asp Lys Val Ser Pro Leu Gln Asn Leu Ala Ser Ile Asn Asn Lys Lys 
        435                 440                 445             


Glu Tyr Ser Asn His Ser Ile Phe Ser Pro Ser Leu Glu Glu Gln Thr 
    450                 455                 460                 


Ala Val Ser Gly Ala Val Asn Asp Ser Ile Lys Ala Ile Ala Ser Ile 
465                 470                 475                 480 


Ala Glu Lys Tyr Phe Gly Ser Thr Gly Leu Val Gly Leu Gln Asp Lys 
                485                 490                 495     


Lys Val Gly Ala Leu Pro Tyr Pro Ser Met Phe Pro Leu Pro Phe Phe 
            500                 505                 510         


Pro Ala Phe Ser Gln Ser Met Tyr Pro Phe Pro Asp Arg Asp Leu Arg 
        515                 520                 525             


Ser Leu Pro Leu Lys Met Glu Pro Gln Ser Pro Gly Glu Val Lys Lys 
    530                 535                 540                 


Leu Gln Lys Gly Ser Ser Glu Ser Pro Phe Asp Leu Thr Thr Lys Arg 
545                 550                 555                 560 


Lys Asp Glu Lys Pro Leu Thr Pro Val Pro Ser Lys Pro Pro Val Thr 
                565                 570                 575     


Pro Ala Thr Ser Gln Asp Gln Pro Leu Asp Leu Ser Met Gly Ser Arg 
            580                 585                 590         


Ser Arg Ala Ser Gly Thr Lys Leu Thr Glu Pro Arg Lys Asn His Val 
        595                 600                 605             


Phe Gly Gly Lys Lys Gly Ser Asn Val Glu Ser Arg Pro Ala Ser Asp 
    610                 615                 620                 


Gly Ser Leu Gln His Ala Arg Pro Thr Pro Phe Phe Met Asp Pro Ile 
625                 630                 635                 640 


Tyr Arg Val Glu Lys Arg Lys Leu Thr Asp Pro Leu Glu Ala Leu Lys 
                645                 650                 655     


Glu Lys Tyr Leu Arg Pro Ser Pro Gly Phe Leu Phe His Pro Gln Phe 
            660                 665                 670         


Gln Leu Pro Asp Gln Arg Thr Trp Met Ser Ala Ile Glu Asn Met Ala 
        675                 680                 685             


Glu Lys Leu Glu Ser Phe Ser Ala Leu Lys Pro Glu Ala Ser Glu Leu 
    690                 695                 700                 


Leu Gln Ser Val Pro Ser Met Phe Asn Phe Arg Ala Pro Pro Asn Ala 
705                 710                 715                 720 


Leu Pro Glu Asn Leu Leu Arg Lys Gly Lys Glu Arg Tyr Thr Cys Arg 
                725                 730                 735     


Tyr Cys Gly Lys Ile Phe Pro Arg Ser Ala Asn Leu Thr Arg His Leu 
            740                 745                 750         


Arg Thr His Thr Gly Glu Gln Pro Tyr Arg Cys Lys Tyr Cys Asp Arg 
        755                 760                 765             


Ser Phe Ser Ile Ser Ser Asn Leu Gln Arg His Val Arg Asn Ile His 
    770                 775                 780                 


Asn Lys Glu Lys Pro Phe Lys Cys His Leu Cys Asp Arg Cys Phe Gly 
785                 790                 795                 800 


Gln Gln Thr Asn Leu Asp Arg His Leu Lys Lys His Glu Asn Gly Asn 
                805                 810                 815     


Met Ser Gly Thr Ala Thr Ser Ser Pro His Ser Glu Leu Glu Ser Thr 
            820                 825                 830         


Gly Ala Ile Leu Asp Asp Lys Glu Asp Ala Tyr Phe Thr Glu Ile Arg 
        835                 840                 845             


Asn Phe Ile Gly Asn Ser Asn His Gly Ser Gln Ser Pro Arg Asn Val 
    850                 855                 860                 


Glu Glu Arg Met Asn Gly Ser His Phe Lys Asp Glu Lys Ala Leu Val 
865                 870                 875                 880 


Thr Ser Gln Asn Ser Asp Leu Leu Asp Asp Glu Glu Val Glu Asp Glu 
                885                 890                 895     


Val Leu Leu Asp Glu Glu Asp Glu Asp Asn Asp Ile Thr Gly Lys Thr 
            900                 905                 910         


Gly Lys Glu Pro Val Thr Ser Asn Leu His Glu Gly Asn Pro Glu Asp 
        915                 920                 925             


Asp Tyr Glu Glu Thr Ser Ala Leu Glu Met Ser Cys Lys Thr Ser Pro 
    930                 935                 940                 


Val Arg Tyr Lys Glu Glu Glu Tyr Lys Ser Gly Leu Ser Ala Leu Asp 
945                 950                 955                 960 


His Ile Arg His Phe Thr Asp Ser Leu Lys Met Arg Lys Met Glu Asp 
                965                 970                 975     


Asn Gln Tyr Ser Glu Ala Glu Leu Ser Ser Phe Ser Thr Ser His Val 
            980                 985                 990         


Pro Glu Glu Leu Lys Gln Pro Leu  His Arg Lys Ser Lys  Ser Gln Ala 
        995                 1000                 1005             


Tyr Ala  Met Met Leu Ser Leu  Ser Asp Lys Glu Ser  Leu His Ser 
    1010                 1015                 1020             


Thr Ser  His Ser Ser Ser Asn  Val Trp His Ser Met  Ala Arg Ala 
    1025                 1030                 1035             


Ala Ala  Glu Ser Ser Ala Ile  Gln Ser Ile Ser His  Val 
    1040                 1045                 1050     


<210>  4143
<211>  1116
<212>  PRT
<213>  homo sapiens

<400>  4143

Met Ile Leu Asp Glu Phe Tyr Asn Val Lys Phe Cys Ile Asp Ala Ser 
1               5                   10                  15      


Gln Pro Asp Val Gly Ser Trp Leu Lys Tyr Ile Arg Phe Ala Gly Cys 
            20                  25                  30          


Tyr Asp Gln His Asn Leu Val Ala Cys Gln Ile Asn Asp Gln Ile Phe 
        35                  40                  45              


Tyr Arg Val Val Ala Asp Ile Ala Pro Gly Glu Glu Leu Leu Leu Phe 
    50                  55                  60                  


Met Lys Ser Glu Asp Tyr Pro His Glu Thr Met Ala Pro Asp Ile His 
65                  70                  75                  80  


Glu Glu Arg Gln Tyr Arg Cys Glu Asp Cys Asp Gln Leu Phe Glu Ser 
                85                  90                  95      


Lys Ala Glu Leu Ala Asp His Gln Lys Phe Pro Cys Ser Thr Pro His 
            100                 105                 110         


Ser Ala Phe Ser Met Val Glu Glu Asp Phe Gln Gln Lys Leu Glu Ser 
        115                 120                 125             


Glu Asn Asp Leu Gln Glu Ile His Thr Ile Gln Glu Cys Lys Glu Cys 
    130                 135                 140                 


Asp Gln Val Phe Pro Asp Leu Gln Ser Leu Glu Lys His Met Leu Ser 
145                 150                 155                 160 


His Thr Glu Glu Arg Glu Tyr Lys Cys Asp Gln Cys Pro Lys Ala Phe 
                165                 170                 175     


Asn Trp Lys Ser Asn Leu Ile Arg His Gln Met Ser His Asp Ser Gly 
            180                 185                 190         


Lys His Tyr Glu Cys Glu Asn Cys Ala Lys Gln Val Phe Thr Asp Pro 
        195                 200                 205             


Ser Asn Leu Gln Arg His Ile Arg Ser Gln His Val Gly Ala Arg Ala 
    210                 215                 220                 


His Ala Cys Pro Glu Cys Gly Lys Thr Phe Ala Thr Ser Ser Gly Leu 
225                 230                 235                 240 


Lys Gln His Lys His Ile His Ser Ser Val Lys Pro Phe Ile Cys Glu 
                245                 250                 255     


Val Cys His Lys Ser Tyr Thr Gln Phe Ser Asn Leu Cys Arg His Lys 
            260                 265                 270         


Arg Met His Ala Asp Cys Arg Thr Gln Ile Lys Cys Lys Asp Cys Gly 
        275                 280                 285             


Gln Met Phe Ser Thr Thr Ser Ser Leu Asn Lys His Arg Arg Phe Cys 
    290                 295                 300                 


Glu Gly Lys Asn His Phe Ala Ala Gly Gly Phe Phe Gly Gln Gly Ile 
305                 310                 315                 320 


Ser Leu Pro Gly Thr Pro Ala Met Asp Lys Thr Ser Met Val Asn Met 
                325                 330                 335     


Ser His Ala Asn Pro Gly Leu Ala Asp Tyr Phe Gly Ala Asn Arg His 
            340                 345                 350         


Pro Ala Gly Leu Thr Phe Pro Thr Ala Pro Gly Phe Ser Phe Ser Phe 
        355                 360                 365             


Pro Gly Leu Phe Pro Ser Gly Leu Tyr His Arg Pro Pro Leu Ile Pro 
    370                 375                 380                 


Ala Ser Ser Pro Val Lys Gly Leu Ser Ser Thr Glu Gln Thr Asn Lys 
385                 390                 395                 400 


Ser Gln Ser Pro Leu Met Thr His Pro Gln Ile Leu Pro Ala Thr Gln 
                405                 410                 415     


Asp Ile Leu Lys Ala Leu Ser Lys His Pro Ser Val Gly Asp Asn Lys 
            420                 425                 430         


Pro Val Glu Leu Gln Pro Glu Arg Ser Ser Glu Glu Arg Pro Phe Glu 
        435                 440                 445             


Lys Ile Ser Asp Gln Ser Glu Ser Ser Asp Leu Asp Asp Val Ser Thr 
    450                 455                 460                 


Pro Ser Gly Ser Asp Leu Glu Thr Thr Ser Gly Ser Asp Leu Glu Ser 
465                 470                 475                 480 


Asp Ile Glu Ser Asp Lys Glu Lys Phe Lys Glu Asn Gly Lys Met Phe 
                485                 490                 495     


Lys Asp Lys Val Ser Pro Leu Gln Asn Leu Ala Ser Ile Asn Asn Lys 
            500                 505                 510         


Lys Glu Tyr Ser Asn His Ser Ile Phe Ser Pro Ser Leu Glu Glu Gln 
        515                 520                 525             


Thr Ala Val Ser Gly Ala Val Asn Asp Ser Ile Lys Ala Ile Ala Ser 
    530                 535                 540                 


Ile Ala Glu Lys Tyr Phe Gly Ser Thr Gly Leu Val Gly Leu Gln Asp 
545                 550                 555                 560 


Lys Lys Val Gly Ala Leu Pro Tyr Pro Ser Met Phe Pro Leu Pro Phe 
                565                 570                 575     


Phe Pro Ala Phe Ser Gln Ser Met Tyr Pro Phe Pro Asp Arg Asp Leu 
            580                 585                 590         


Arg Ser Leu Pro Leu Lys Met Glu Pro Gln Ser Pro Gly Glu Val Lys 
        595                 600                 605             


Lys Leu Gln Lys Gly Ser Ser Glu Ser Pro Phe Asp Leu Thr Thr Lys 
    610                 615                 620                 


Arg Lys Asp Glu Lys Pro Leu Thr Pro Val Pro Ser Lys Pro Pro Val 
625                 630                 635                 640 


Thr Pro Ala Thr Ser Gln Asp Gln Pro Leu Asp Leu Ser Met Gly Ser 
                645                 650                 655     


Arg Ser Arg Ala Ser Gly Thr Lys Leu Thr Glu Pro Arg Lys Asn His 
            660                 665                 670         


Val Phe Gly Gly Lys Lys Gly Ser Asn Val Glu Ser Arg Pro Ala Ser 
        675                 680                 685             


Asp Gly Ser Leu Gln His Ala Arg Pro Thr Pro Phe Phe Met Asp Pro 
    690                 695                 700                 


Ile Tyr Arg Val Glu Lys Arg Lys Leu Thr Asp Pro Leu Glu Ala Leu 
705                 710                 715                 720 


Lys Glu Lys Tyr Leu Arg Pro Ser Pro Gly Phe Leu Phe His Pro Gln 
                725                 730                 735     


Phe Gln Leu Pro Asp Gln Arg Thr Trp Met Ser Ala Ile Glu Asn Met 
            740                 745                 750         


Ala Glu Lys Leu Glu Ser Phe Ser Ala Leu Lys Pro Glu Ala Ser Glu 
        755                 760                 765             


Leu Leu Gln Ser Val Pro Ser Met Phe Asn Phe Arg Ala Pro Pro Asn 
    770                 775                 780                 


Ala Leu Pro Glu Asn Leu Leu Arg Lys Gly Lys Glu Arg Tyr Thr Cys 
785                 790                 795                 800 


Arg Tyr Cys Gly Lys Ile Phe Pro Arg Ser Ala Asn Leu Thr Arg His 
                805                 810                 815     


Leu Arg Thr His Thr Gly Glu Gln Pro Tyr Arg Cys Lys Tyr Cys Asp 
            820                 825                 830         


Arg Ser Phe Ser Ile Ser Ser Asn Leu Gln Arg His Val Arg Asn Ile 
        835                 840                 845             


His Asn Lys Glu Lys Pro Phe Lys Cys His Leu Cys Asp Arg Cys Phe 
    850                 855                 860                 


Gly Gln Gln Thr Asn Leu Asp Arg His Leu Lys Lys His Glu Asn Gly 
865                 870                 875                 880 


Asn Met Ser Gly Thr Ala Thr Ser Ser Pro His Ser Glu Leu Glu Ser 
                885                 890                 895     


Thr Gly Ala Ile Leu Asp Asp Lys Glu Asp Ala Tyr Phe Thr Glu Ile 
            900                 905                 910         


Arg Asn Phe Ile Gly Asn Ser Asn His Gly Ser Gln Ser Pro Arg Asn 
        915                 920                 925             


Val Glu Glu Arg Met Asn Gly Ser His Phe Lys Asp Glu Lys Ala Leu 
    930                 935                 940                 


Val Thr Ser Gln Asn Ser Asp Leu Leu Asp Asp Glu Glu Val Glu Asp 
945                 950                 955                 960 


Glu Val Leu Leu Asp Glu Glu Asp Glu Asp Asn Asp Ile Thr Gly Lys 
                965                 970                 975     


Thr Gly Lys Glu Pro Val Thr Ser Asn Leu His Glu Gly Asn Pro Glu 
            980                 985                 990         


Asp Asp Tyr Glu Glu Thr Ser Ala  Leu Glu Met Ser Cys  Lys Thr Ser 
        995                 1000                 1005             


Pro Val  Arg Tyr Lys Glu Glu  Glu Tyr Lys Ser Gly  Leu Ser Ala 
    1010                 1015                 1020             


Leu Asp  His Ile Arg His Phe  Thr Asp Ser Leu Lys  Met Arg Lys 
    1025                 1030                 1035             


Met Glu  Asp Asn Gln Tyr Ser  Glu Ala Glu Leu Ser  Ser Phe Ser 
    1040                 1045                 1050             


Thr Ser  His Val Pro Glu Glu  Leu Lys Gln Pro Leu  His Arg Lys 
    1055                 1060                 1065             


Ser Lys  Ser Gln Ala Tyr Ala  Met Met Leu Ser Leu  Ser Asp Lys 
    1070                 1075                 1080             


Glu Ser  Leu His Ser Thr Ser  His Ser Ser Ser Asn  Val Trp His 
    1085                 1090                 1095             


Ser Met  Ala Arg Ala Ala Ala  Glu Ser Ser Ala Ile  Gln Ser Ile 
    1100                 1105                 1110             


Ser His  Val 
    1115     


<210>  4144
<211>  1239
<212>  PRT
<213>  homo sapiens

<400>  4144

Met Arg Ser Lys Gly Arg Ala Arg Lys Leu Ala Thr Asn Asn Glu Cys 
1               5                   10                  15      


Val Tyr Gly Asn Tyr Pro Glu Ile Pro Leu Glu Glu Met Pro Asp Ala 
            20                  25                  30          


Asp Gly Val Ala Ser Thr Pro Ser Leu Asn Ile Gln Glu Pro Cys Ser 
        35                  40                  45              


Pro Ala Thr Ser Ser Glu Ala Phe Thr Pro Lys Glu Gly Ser Pro Tyr 
    50                  55                  60                  


Lys Ala Pro Ile Tyr Ile Pro Asp Asp Ile Pro Ile Pro Ala Glu Phe 
65                  70                  75                  80  


Glu Leu Arg Glu Ser Asn Met Pro Gly Ala Gly Leu Gly Ile Trp Thr 
                85                  90                  95      


Lys Arg Lys Ile Glu Val Gly Glu Lys Phe Gly Pro Tyr Val Gly Glu 
            100                 105                 110         


Gln Arg Ser Asn Leu Lys Asp Pro Ser Tyr Gly Trp Glu Ile Leu Asp 
        115                 120                 125             


Glu Phe Tyr Asn Val Lys Phe Cys Ile Asp Ala Ser Gln Pro Asp Val 
    130                 135                 140                 


Gly Ser Trp Leu Lys Tyr Ile Arg Phe Ala Gly Cys Tyr Asp Gln His 
145                 150                 155                 160 


Asn Leu Val Ala Cys Gln Ile Asn Asp Gln Ile Phe Tyr Arg Val Val 
                165                 170                 175     


Ala Asp Ile Ala Pro Gly Glu Glu Leu Leu Leu Phe Met Lys Ser Glu 
            180                 185                 190         


Asp Tyr Pro His Glu Thr Met Ala Pro Asp Ile His Glu Glu Arg Gln 
        195                 200                 205             


Tyr Arg Cys Glu Asp Cys Asp Gln Leu Phe Glu Ser Lys Ala Glu Leu 
    210                 215                 220                 


Ala Asp His Gln Lys Phe Pro Cys Ser Thr Pro His Ser Ala Phe Ser 
225                 230                 235                 240 


Met Val Glu Glu Asp Phe Gln Gln Lys Leu Glu Ser Glu Asn Asp Leu 
                245                 250                 255     


Gln Glu Ile His Thr Ile Gln Glu Cys Lys Glu Cys Asp Gln Val Phe 
            260                 265                 270         


Pro Asp Leu Gln Ser Leu Glu Lys His Met Leu Ser His Thr Glu Glu 
        275                 280                 285             


Arg Glu Tyr Lys Cys Asp Gln Cys Pro Lys Ala Phe Asn Trp Lys Ser 
    290                 295                 300                 


Asn Leu Ile Arg His Gln Met Ser His Asp Ser Gly Lys His Tyr Glu 
305                 310                 315                 320 


Cys Glu Asn Cys Ala Lys Val Phe Thr Asp Pro Ser Asn Leu Gln Arg 
                325                 330                 335     


His Ile Arg Ser Gln His Val Gly Ala Arg Ala His Ala Cys Pro Glu 
            340                 345                 350         


Cys Gly Lys Thr Phe Ala Thr Ser Ser Gly Leu Lys Gln His Lys His 
        355                 360                 365             


Ile His Ser Ser Val Lys Pro Phe Ile Cys Glu Val Cys His Lys Ser 
    370                 375                 380                 


Tyr Thr Gln Phe Ser Asn Leu Cys Arg His Lys Arg Met His Ala Asp 
385                 390                 395                 400 


Cys Arg Thr Gln Ile Lys Cys Lys Asp Cys Gly Gln Met Phe Ser Thr 
                405                 410                 415     


Thr Ser Ser Leu Asn Lys His Arg Arg Phe Cys Glu Gly Lys Asn His 
            420                 425                 430         


Phe Ala Ala Gly Gly Phe Phe Gly Gln Gly Ile Ser Leu Pro Gly Thr 
        435                 440                 445             


Pro Ala Met Asp Lys Thr Ser Met Val Asn Met Ser His Ala Asn Pro 
    450                 455                 460                 


Gly Leu Ala Asp Tyr Phe Gly Ala Asn Arg His Pro Ala Gly Leu Thr 
465                 470                 475                 480 


Phe Pro Thr Ala Pro Gly Phe Ser Phe Ser Phe Pro Gly Leu Phe Pro 
                485                 490                 495     


Ser Gly Leu Tyr His Arg Pro Pro Leu Ile Pro Ala Ser Ser Pro Val 
            500                 505                 510         


Lys Gly Leu Ser Ser Thr Glu Gln Thr Asn Lys Ser Gln Ser Pro Leu 
        515                 520                 525             


Met Thr His Pro Gln Ile Leu Pro Ala Thr Gln Asp Ile Leu Lys Ala 
    530                 535                 540                 


Leu Ser Lys His Pro Ser Val Gly Asp Asn Lys Pro Val Glu Leu Gln 
545                 550                 555                 560 


Pro Glu Arg Ser Ser Glu Glu Arg Pro Phe Glu Lys Ile Ser Asp Gln 
                565                 570                 575     


Ser Glu Ser Ser Asp Leu Asp Asp Val Ser Thr Pro Ser Gly Ser Asp 
            580                 585                 590         


Leu Glu Thr Thr Ser Gly Ser Asp Leu Glu Ser Asp Ile Glu Ser Asp 
        595                 600                 605             


Lys Glu Lys Phe Lys Glu Asn Gly Lys Met Phe Lys Asp Lys Val Ser 
    610                 615                 620                 


Pro Leu Gln Asn Leu Ala Ser Ile Asn Asn Lys Lys Glu Tyr Ser Asn 
625                 630                 635                 640 


His Ser Ile Phe Ser Pro Ser Leu Glu Glu Gln Thr Ala Val Ser Gly 
                645                 650                 655     


Ala Val Asn Asp Ser Ile Lys Ala Ile Ala Ser Ile Ala Glu Lys Tyr 
            660                 665                 670         


Phe Gly Ser Thr Gly Leu Val Gly Leu Gln Asp Lys Lys Val Gly Ala 
        675                 680                 685             


Leu Pro Tyr Pro Ser Met Phe Pro Leu Pro Phe Phe Pro Ala Phe Ser 
    690                 695                 700                 


Gln Ser Met Tyr Pro Phe Pro Asp Arg Asp Leu Arg Ser Leu Pro Leu 
705                 710                 715                 720 


Lys Met Glu Pro Gln Ser Pro Gly Glu Val Lys Lys Leu Gln Lys Gly 
                725                 730                 735     


Ser Ser Glu Ser Pro Phe Asp Leu Thr Thr Lys Arg Lys Asp Glu Lys 
            740                 745                 750         


Pro Leu Thr Pro Val Pro Ser Lys Pro Pro Val Thr Pro Ala Thr Ser 
        755                 760                 765             


Gln Asp Gln Pro Leu Asp Leu Ser Met Gly Ser Arg Ser Arg Ala Ser 
    770                 775                 780                 


Gly Thr Lys Leu Thr Glu Pro Arg Lys Asn His Val Phe Gly Gly Lys 
785                 790                 795                 800 


Lys Gly Ser Asn Val Glu Ser Arg Pro Ala Ser Asp Gly Ser Leu Gln 
                805                 810                 815     


His Ala Arg Pro Thr Pro Phe Phe Met Asp Pro Ile Tyr Arg Val Glu 
            820                 825                 830         


Lys Arg Lys Leu Thr Asp Pro Leu Glu Ala Leu Lys Glu Lys Tyr Leu 
        835                 840                 845             


Arg Pro Ser Pro Gly Phe Leu Phe His Pro Gln Phe Gln Leu Pro Asp 
    850                 855                 860                 


Gln Arg Thr Trp Met Ser Ala Ile Glu Asn Met Ala Glu Lys Leu Glu 
865                 870                 875                 880 


Ser Phe Ser Ala Leu Lys Pro Glu Ala Ser Glu Leu Leu Gln Ser Val 
                885                 890                 895     


Pro Ser Met Phe Asn Phe Arg Ala Pro Pro Asn Ala Leu Pro Glu Asn 
            900                 905                 910         


Leu Leu Arg Lys Gly Lys Glu Arg Tyr Thr Cys Arg Tyr Cys Gly Lys 
        915                 920                 925             


Ile Phe Pro Arg Ser Ala Asn Leu Thr Arg His Leu Arg Thr His Thr 
    930                 935                 940                 


Gly Glu Gln Pro Tyr Arg Cys Lys Tyr Cys Asp Arg Ser Phe Ser Ile 
945                 950                 955                 960 


Ser Ser Asn Leu Gln Arg His Val Arg Asn Ile His Asn Lys Glu Lys 
                965                 970                 975     


Pro Phe Lys Cys His Leu Cys Asp Arg Cys Phe Gly Gln Gln Thr Asn 
            980                 985                 990         


Leu Asp Arg His Leu Lys Lys His  Glu Asn Gly Asn Met  Ser Gly Thr 
        995                 1000                 1005             


Ala Thr  Ser Ser Pro His Ser  Glu Leu Glu Ser Thr  Gly Ala Ile 
    1010                 1015                 1020             


Leu Asp  Asp Lys Glu Asp Ala  Tyr Phe Thr Glu Ile  Arg Asn Phe 
    1025                 1030                 1035             


Ile Gly  Asn Ser Asn His Gly  Ser Gln Ser Pro Arg  Asn Val Glu 
    1040                 1045                 1050             


Glu Arg  Met Asn Gly Ser His  Phe Lys Asp Glu Lys  Ala Leu Val 
    1055                 1060                 1065             


Thr Ser  Gln Asn Ser Asp Leu  Leu Asp Asp Glu Glu  Val Glu Asp 
    1070                 1075                 1080             


Glu Val  Leu Leu Asp Glu Glu  Asp Glu Asp Asn Asp  Ile Thr Gly 
    1085                 1090                 1095             


Lys Thr  Gly Lys Glu Pro Val  Thr Ser Asn Leu His  Glu Gly Asn 
    1100                 1105                 1110             


Pro Glu  Asp Asp Tyr Glu Glu  Thr Ser Ala Leu Glu  Met Ser Cys 
    1115                 1120                 1125             


Lys Thr  Ser Pro Val Arg Tyr  Lys Glu Glu Glu Tyr  Lys Ser Gly 
    1130                 1135                 1140             


Leu Ser  Ala Leu Asp His Ile  Arg His Phe Thr Asp  Ser Leu Lys 
    1145                 1150                 1155             


Met Arg  Lys Met Glu Asp Asn  Gln Tyr Ser Glu Ala  Glu Leu Ser 
    1160                 1165                 1170             


Ser Phe  Ser Thr Ser His Val  Pro Glu Glu Leu Lys  Gln Pro Leu 
    1175                 1180                 1185             


His Arg  Lys Ser Lys Ser Gln  Ala Tyr Ala Met Met  Leu Ser Leu 
    1190                 1195                 1200             


Ser Asp  Lys Glu Ser Leu His  Ser Thr Ser His Ser  Ser Ser Asn 
    1205                 1210                 1215             


Val Trp  His Ser Met Ala Arg  Ala Ala Ala Glu Ser  Ser Ala Ile 
    1220                 1225                 1230             


Gln Ser  Ile Ser His Val 
    1235                 


<210>  4145
<211>  1043
<212>  PRT
<213>  homo sapiens

<400>  4145

Met Lys Ser Glu Asp Tyr Pro His Glu Thr Met Ala Pro Asp Ile His 
1               5                   10                  15      


Glu Glu Arg Gln Tyr Arg Cys Glu Asp Cys Asp Gln Leu Phe Glu Ser 
            20                  25                  30          


Lys Ala Glu Leu Ala Asp His Gln Lys Phe Pro Cys Ser Thr Pro His 
        35                  40                  45              


Ser Ala Phe Ser Met Val Glu Glu Asp Phe Gln Gln Lys Leu Glu Ser 
    50                  55                  60                  


Glu Asn Asp Leu Gln Glu Ile His Thr Ile Gln Glu Cys Lys Glu Cys 
65                  70                  75                  80  


Asp Gln Val Phe Pro Asp Leu Gln Ser Leu Glu Lys His Met Leu Ser 
                85                  90                  95      


His Thr Glu Glu Arg Glu Tyr Lys Cys Asp Gln Cys Pro Lys Ala Phe 
            100                 105                 110         


Asn Trp Lys Ser Asn Leu Ile Arg His Gln Met Ser His Asp Ser Gly 
        115                 120                 125             


Lys His Tyr Glu Cys Glu Asn Cys Ala Lys Gln Val Phe Thr Asp Pro 
    130                 135                 140                 


Ser Asn Leu Gln Arg His Ile Arg Ser Gln His Val Gly Ala Arg Ala 
145                 150                 155                 160 


His Ala Cys Pro Glu Cys Gly Lys Thr Phe Ala Thr Ser Ser Gly Leu 
                165                 170                 175     


Lys Gln His Lys His Ile His Ser Ser Val Lys Pro Phe Ile Cys Glu 
            180                 185                 190         


Val Cys His Lys Ser Tyr Thr Gln Phe Ser Asn Leu Cys Arg His Lys 
        195                 200                 205             


Arg Met His Ala Asp Cys Arg Thr Gln Ile Lys Cys Lys Asp Cys Gly 
    210                 215                 220                 


Gln Met Phe Ser Thr Thr Ser Ser Leu Asn Lys His Arg Arg Phe Cys 
225                 230                 235                 240 


Glu Gly Lys Asn His Phe Ala Ala Gly Gly Phe Phe Gly Gln Gly Ile 
                245                 250                 255     


Ser Leu Pro Gly Thr Pro Ala Met Asp Lys Thr Ser Met Val Asn Met 
            260                 265                 270         


Ser His Ala Asn Pro Gly Leu Ala Asp Tyr Phe Gly Ala Asn Arg His 
        275                 280                 285             


Pro Ala Gly Leu Thr Phe Pro Thr Ala Pro Gly Phe Ser Phe Ser Phe 
    290                 295                 300                 


Pro Gly Leu Phe Pro Ser Gly Leu Tyr His Arg Pro Pro Leu Ile Pro 
305                 310                 315                 320 


Ala Ser Ser Pro Val Lys Gly Leu Ser Ser Thr Glu Gln Thr Asn Lys 
                325                 330                 335     


Ser Gln Ser Pro Leu Met Thr His Pro Gln Ile Leu Pro Ala Thr Gln 
            340                 345                 350         


Asp Ile Leu Lys Ala Leu Ser Lys His Pro Ser Val Gly Asp Asn Lys 
        355                 360                 365             


Pro Val Glu Leu Gln Pro Glu Arg Ser Ser Glu Glu Arg Pro Phe Glu 
    370                 375                 380                 


Lys Ile Ser Asp Gln Ser Glu Ser Ser Asp Leu Asp Asp Val Ser Thr 
385                 390                 395                 400 


Pro Ser Gly Ser Asp Leu Glu Thr Thr Ser Gly Ser Asp Leu Glu Ser 
                405                 410                 415     


Asp Ile Glu Ser Asp Lys Glu Lys Phe Lys Glu Asn Gly Lys Met Phe 
            420                 425                 430         


Lys Asp Lys Val Ser Pro Leu Gln Asn Leu Ala Ser Ile Asn Asn Lys 
        435                 440                 445             


Lys Glu Tyr Ser Asn His Ser Ile Phe Ser Pro Ser Leu Glu Glu Gln 
    450                 455                 460                 


Thr Ala Val Ser Gly Ala Val Asn Asp Ser Ile Lys Ala Ile Ala Ser 
465                 470                 475                 480 


Ile Ala Glu Lys Tyr Phe Gly Ser Thr Gly Leu Val Gly Leu Gln Asp 
                485                 490                 495     


Lys Lys Val Gly Ala Leu Pro Tyr Pro Ser Met Phe Pro Leu Pro Phe 
            500                 505                 510         


Phe Pro Ala Phe Ser Gln Ser Met Tyr Pro Phe Pro Asp Arg Asp Leu 
        515                 520                 525             


Arg Ser Leu Pro Leu Lys Met Glu Pro Gln Ser Pro Gly Glu Val Lys 
    530                 535                 540                 


Lys Leu Gln Lys Gly Ser Ser Glu Ser Pro Phe Asp Leu Thr Thr Lys 
545                 550                 555                 560 


Arg Lys Asp Glu Lys Pro Leu Thr Pro Val Pro Ser Lys Pro Pro Val 
                565                 570                 575     


Thr Pro Ala Thr Ser Gln Asp Gln Pro Leu Asp Leu Ser Met Gly Ser 
            580                 585                 590         


Arg Ser Arg Ala Ser Gly Thr Lys Leu Thr Glu Pro Arg Lys Asn His 
        595                 600                 605             


Val Phe Gly Gly Lys Lys Gly Ser Asn Val Glu Ser Arg Pro Ala Ser 
    610                 615                 620                 


Asp Gly Ser Leu Gln His Ala Arg Pro Thr Pro Phe Phe Met Asp Pro 
625                 630                 635                 640 


Ile Tyr Arg Val Glu Lys Arg Lys Leu Thr Asp Pro Leu Glu Ala Leu 
                645                 650                 655     


Lys Glu Lys Tyr Leu Arg Pro Ser Pro Gly Phe Leu Phe His Pro Gln 
            660                 665                 670         


Met Ser Ala Ile Glu Asn Met Ala Glu Lys Leu Glu Ser Phe Ser Ala 
        675                 680                 685             


Leu Lys Pro Glu Ala Ser Glu Leu Leu Gln Ser Val Pro Ser Met Phe 
    690                 695                 700                 


Asn Phe Arg Ala Pro Pro Asn Ala Leu Pro Glu Asn Leu Leu Arg Lys 
705                 710                 715                 720 


Gly Lys Glu Arg Tyr Thr Cys Arg Tyr Cys Gly Lys Ile Phe Pro Arg 
                725                 730                 735     


Ser Ala Asn Leu Thr Arg His Leu Arg Thr His Thr Gly Glu Gln Pro 
            740                 745                 750         


Tyr Arg Cys Lys Tyr Cys Asp Arg Ser Phe Ser Ile Ser Ser Asn Leu 
        755                 760                 765             


Gln Arg His Val Arg Asn Ile His Asn Lys Glu Lys Pro Phe Lys Cys 
    770                 775                 780                 


His Leu Cys Asp Arg Cys Phe Gly Gln Gln Thr Asn Leu Asp Arg His 
785                 790                 795                 800 


Leu Lys Lys His Glu Asn Gly Asn Met Ser Gly Thr Ala Thr Ser Ser 
                805                 810                 815     


Pro His Ser Glu Leu Glu Ser Thr Gly Ala Ile Leu Asp Asp Lys Glu 
            820                 825                 830         


Asp Ala Tyr Phe Thr Glu Ile Arg Asn Phe Ile Gly Asn Ser Asn His 
        835                 840                 845             


Gly Ser Gln Ser Pro Arg Asn Val Glu Glu Arg Met Asn Gly Ser His 
    850                 855                 860                 


Phe Lys Asp Glu Lys Ala Leu Val Thr Ser Gln Asn Ser Asp Leu Leu 
865                 870                 875                 880 


Asp Asp Glu Glu Val Glu Asp Glu Val Leu Leu Asp Glu Glu Asp Glu 
                885                 890                 895     


Asp Asn Asp Ile Thr Gly Lys Thr Gly Lys Glu Pro Val Thr Ser Asn 
            900                 905                 910         


Leu His Glu Gly Asn Pro Glu Asp Asp Tyr Glu Glu Thr Ser Ala Leu 
        915                 920                 925             


Glu Met Ser Cys Lys Thr Ser Pro Val Arg Tyr Lys Glu Glu Glu Tyr 
    930                 935                 940                 


Lys Ser Gly Leu Ser Ala Leu Asp His Ile Arg His Phe Thr Asp Ser 
945                 950                 955                 960 


Leu Lys Met Arg Lys Met Glu Asp Asn Gln Tyr Ser Glu Ala Glu Leu 
                965                 970                 975     


Ser Ser Phe Ser Thr Ser His Val Pro Glu Glu Leu Lys Gln Pro Leu 
            980                 985                 990         


His Arg Lys Ser Lys Ser Gln Ala  Tyr Ala Met Met Leu  Ser Leu Ser 
        995                 1000                 1005             


Asp Lys  Glu Ser Leu His Ser  Thr Ser His Ser Ser  Ser Asn Val 
    1010                 1015                 1020             


Trp His  Ser Met Ala Arg Ala  Ala Ala Glu Ser Ser  Ala Ile Gln 
    1025                 1030                 1035             


Ser Ile  Ser His Val 
    1040             


<210>  4146
<211>  2046
<212>  PRT
<213>  homo sapiens

<400>  4146

Met Glu Leu Ala His Ser Leu Leu Leu Asn Glu Glu Ala Tyr Asn Gln 
1               5                   10                  15      


Leu Gly Glu Val Gln Lys Ala Glu Phe Ile Phe Glu Trp Leu Arg Tyr 
            20                  25                  30          


Leu Glu Lys Leu Leu Leu Ala Thr Ser Arg Asn Asp Val Arg Glu Lys 
        35                  40                  45              


Gln Lys Thr Leu Val Glu Gln Leu Leu Ser Leu Leu Asn Ser Ser Pro 
    50                  55                  60                  


Gly Pro Pro Thr Arg Lys Leu Leu Ala Lys Asn Leu Ala Ile Leu Tyr 
65                  70                  75                  80  


Ser Ile Gly Asp Thr Phe Ser Val His Glu Ala Ile Asp Lys Cys Asn 
                85                  90                  95      


Asp Leu Ile Arg Ser Lys Asp Asp Ser Pro Ser Tyr Leu Pro Thr Lys 
            100                 105                 110         


Leu Ala Ala Val Val Cys Leu Gly Ser Leu Tyr Lys Lys Leu Gly Arg 
        115                 120                 125             


Ile Leu Gly Asn Thr Phe Thr Asp Thr Val Gly Asn Ile Leu Lys Ala 
    130                 135                 140                 


Met Lys Ser Ala Glu Ser Gln Gly Arg Tyr Glu Ile Met Leu Ser Leu 
145                 150                 155                 160 


Gln Asn Ile Leu Asn Gly Leu Gly Ala Ala Ala Ala Pro Cys His Arg 
                165                 170                 175     


Asp Val Tyr Lys Ala Ala Arg Ser Cys Leu Thr Asp Arg Ser Met Ala 
            180                 185                 190         


Val Arg Cys Ala Ala Ala Lys Cys Leu Leu Glu Leu Gln Asn Glu Ala 
        195                 200                 205             


Ile Phe Met Trp Ser Thr Asp Leu Asp Ser Val Ala Thr Leu Cys Phe 
    210                 215                 220                 


Lys Ser Phe Glu Gly Ser Asn Tyr Asp Val Arg Ile Ser Val Ser Lys 
225                 230                 235                 240 


Leu Leu Gly Ile Ile Leu Ala Lys Ala Val Ile Ser Lys His Pro Gly 
                245                 250                 255     


Thr Ala Ala Ser Arg Gln Ser Ile Arg Arg Val Ser Leu Glu Glu Val 
            260                 265                 270         


Leu Glu Leu Leu Gly Thr Gly Phe Leu Arg Gly Ser Ser Gly Phe Leu 
        275                 280                 285             


Arg Ala Ser Gly Asp Met Leu Lys Gly Thr Ser Ser Val Ser Arg Asp 
    290                 295                 300                 


Val Arg Val Gly Val Thr Gln Ala Tyr Val Val Phe Val Ser Thr Leu 
305                 310                 315                 320 


Gly Gly Ala Trp Leu Glu Lys Asn Phe Ala Ala Phe Phe Ser His Ile 
                325                 330                 335     


Leu Ser Leu Ala Ser Pro Ser His Pro Lys Ala Thr Gln Thr Gln Ile 
            340                 345                 350         


Asp Ala Val Cys Cys Arg Arg Cys Val Ser Phe Ile Leu Arg Thr Thr 
        355                 360                 365             


Ile Gly Gly Leu Leu Gly Glu Lys Ala Gln Leu Ala Ala Val Lys Asp 
    370                 375                 380                 


Ile Cys Gln Ala Ile Trp Lys Leu Lys Lys Val Met Asp Ala Val Met 
385                 390                 395                 400 


Ser Asp Gly Asn Leu Glu Thr Arg Leu Gly Ser Thr Asp Val Ala Ala 
                405                 410                 415     


Ser Gln His Met Leu Val Cys Ala Leu Gln Glu Leu Gly Asn Leu Ile 
            420                 425                 430         


His Asn Leu Gly Thr Thr Ala Ala Pro Leu Leu Gln Asp Ser Ser Thr 
        435                 440                 445             


Gly Leu Leu Asp Ser Ile Leu Ser Val Ile Leu His Pro Ser Ile Ser 
    450                 455                 460                 


Val Arg Leu Ala Ala Ala Trp Cys Leu His Cys Ile Ala Val Ala Leu 
465                 470                 475                 480 


Pro Ser Tyr Leu Thr Pro Leu Leu Asp Arg Cys Leu Glu Arg Leu Thr 
                485                 490                 495     


Gly His Lys Ser Ser Pro Glu Ala Val Thr Gly Phe Ser Phe Ala Val 
            500                 505                 510         


Ala Ala Leu Leu Gly Ala Val Lys His Cys Pro Leu Gly Ile Pro His 
        515                 520                 525             


Gly Lys Gly Lys Ile Ile Met Thr Leu Ala Glu Asp Leu Leu Cys Ser 
    530                 535                 540                 


Ala Ala Gln Asn Ser Arg Leu Ser Ala Gln Arg Thr Gln Ala Gly Trp 
545                 550                 555                 560 


Leu Leu Ile Ser Ala Leu Met Thr Leu Gly Pro Ala Val Val Ser His 
                565                 570                 575     


His Leu Ala Arg Val Leu Leu Leu Trp Lys Cys Val Phe Pro Ala Ser 
            580                 585                 590         


Pro Lys Asp Leu Glu Thr Glu Lys Ser Arg Gly Asp Ser Phe Thr Trp 
        595                 600                 605             


Gln Val Thr Leu Glu Gly Arg Ala Gly Ala Leu Cys Ala Ile Lys Ser 
    610                 615                 620                 


Phe Val Ser His Cys Gly Asp Leu Leu Thr Glu Glu Val Thr Gln Arg 
625                 630                 635                 640 


Leu Leu Pro Pro Leu Pro Cys Ala Val Asp Leu Leu Thr Gln Leu Ser 
                645                 650                 655     


Ser Ile Leu Lys Met Tyr Gly Ser Pro Leu Lys Thr Pro Ser Val Val 
            660                 665                 670         


Tyr Arg Gln Arg Leu Tyr Glu Leu Leu Ile Leu Leu Pro Pro Glu Thr 
        675                 680                 685             


Tyr Glu Gly Asn Leu Cys Ala Ile Leu Arg Glu Leu Ala Ala Asp Leu 
    690                 695                 700                 


Thr Ala Pro Asp Ile Gln Val Ala Ala Ser Thr Phe Leu Leu Pro Pro 
705                 710                 715                 720 


Leu Cys His Gln Asp Asp Leu Leu Ile Leu Ser Pro Phe Leu Gln Glu 
                725                 730                 735     


Thr Asp His Arg Phe Ile Glu Glu Gln Leu Leu Leu Gly Asn Gly Val 
            740                 745                 750         


Ala Cys Gly Ser Leu Glu Tyr Asp Pro Tyr Ser Ile Tyr Glu Lys Asp 
        755                 760                 765             


Val Glu Gly Asp Ser Val Pro Lys Pro Leu Pro Pro Ala Leu Ser Val 
    770                 775                 780                 


Ile Ser Ser Ala Ser Lys Leu Phe Gly Val Val Cys Ala His Val Gly 
785                 790                 795                 800 


Glu Thr Gln Arg Leu Leu Ile Leu Glu Gln Leu Leu Asp Ser Ile Lys 
                805                 810                 815     


His Thr Lys Gly Ala Arg Gln Gln Val Val Gln Leu His Val Val Ser 
            820                 825                 830         


Ser Val Ser Ser Phe Leu Lys Tyr Val Ala Gly Ser Lys Gly Cys Leu 
        835                 840                 845             


Gly Pro Glu Glu Met Lys Arg Phe Ala Leu Thr Leu Val Met Gly Ala 
    850                 855                 860                 


Leu Glu Ser Pro Asn Pro Leu Leu Arg Cys Ala Ala Ala Glu Ser Trp 
865                 870                 875                 880 


Ala Arg Leu Ala Gln Val Val Asp Asp Gly Ala Phe Thr Ala Gly Leu 
                885                 890                 895     


Ala Gln Val Ser Phe Asp Lys Leu Lys Ser Ala Arg Asp Val Val Thr 
            900                 905                 910         


Arg Thr Gly His Ser Leu Ala Leu Gly Ser Leu His Arg Tyr Leu Gly 
        915                 920                 925             


Gly Ile Ser Ser Ser Gln His Leu Asn Ser Cys Ile Gly Ile Leu Tyr 
    930                 935                 940                 


Thr Leu Ala Gln Asp Ser Thr Ser Pro Asp Val Gln Thr Trp Ala Leu 
945                 950                 955                 960 


His Ser Leu Ser Leu Ile Ile Asp Ser Ala Gly Pro Leu Tyr Tyr Val 
                965                 970                 975     


His Val Glu Pro Thr Leu Ser Leu Ile Ile Met Leu Leu Leu Asn Val 
            980                 985                 990         


Pro Pro Thr His Ala Glu Val His  Gln Ser Leu Gly Arg  Cys Leu Asn 
        995                 1000                 1005             


Ala Leu  Ile Thr Thr Leu Gly  Pro Glu Leu Gln Gly  Asn Ser Thr 
    1010                 1015                 1020             


Ser Ile  Ser Thr Leu Arg Thr  Ser Cys Leu Leu Gly  Cys Ala Val 
    1025                 1030                 1035             


Met Gln  Asp Asn Pro Asp Cys  Leu Val Gln Ala Gln  Ala Ile Ser 
    1040                 1045                 1050             


Cys Leu  Gln Gln Leu His Met  Phe Ala Pro Arg His  Val Asn Leu 
    1055                 1060                 1065             


Ser Ser  Leu Val Ser Cys Leu  Cys Val Asn Leu Cys  Ser Pro Tyr 
    1070                 1075                 1080             


Leu Leu  Leu Arg Arg Ala Val  Leu Ala Cys Leu Arg  Gln Leu Val 
    1085                 1090                 1095             


Gln Arg  Glu Ala Ala Glu Val  Ser Glu His Ala Val  Met Leu Ala 
    1100                 1105                 1110             


Lys Asp  Ser Arg Glu Glu Leu  Thr Pro Asp Ala Asn  Ile Arg Glu 
    1115                 1120                 1125             


Val Gly  Leu Glu Gly Ala Leu  Leu Ile Leu Leu Asp  Lys Glu Thr 
    1130                 1135                 1140             


Asp Glu  Arg Leu Cys His Asp  Ile Lys Glu Thr Leu  Asn Tyr Met 
    1145                 1150                 1155             


Leu Thr  Ser Met Ala Val Glu  Lys Leu Ser Leu Trp  Leu Lys Leu 
    1160                 1165                 1170             


Cys Lys  Asp Val Leu Ala Ala  Ser Ala Asp Phe Thr  Ala Val Thr 
    1175                 1180                 1185             


Cys Val  Asp Thr Met Gln Glu  Glu Glu Gly Asp Lys  Gly Asp Asp 
    1190                 1195                 1200             


Ala Ser  Val Leu Thr Thr Arg  Arg Asp Glu Lys Ser  His Pro Phe 
    1205                 1210                 1215             


Thr Asn  Pro Arg Trp Ala Thr  Arg Val Phe Ala Ala  Glu Cys Val 
    1220                 1225                 1230             


Cys Arg  Ile Ile Asn Gln Cys  Glu Asn Ala Asn Ser  Ala His Phe 
    1235                 1240                 1245             


Asp Ile  Ala Leu Ala Gln Glu  Met Lys Lys Arg Asp  Ser Arg Asn 
    1250                 1255                 1260             


Asp Phe  Leu Val Leu His Leu  Ala Asp Leu Ile Arg  Met Ala Phe 
    1265                 1270                 1275             


Met Ala  Ala Thr Asp His Ser  Asp Gln Leu Arg Leu  Ser Gly Leu 
    1280                 1285                 1290             


Glu Met  Leu Leu Val Val Ile  Arg Arg Phe Ala Thr  Val Pro Glu 
    1295                 1300                 1305             


Pro Glu  Phe Pro Gly His Val  Ile Leu Glu Gln Tyr  Gln Ala Asn 
    1310                 1315                 1320             


Val Gly  Ala Ala Leu Arg Pro  Ala Phe Thr Ser Glu  Thr Pro Pro 
    1325                 1330                 1335             


Asp Val  Thr Ala Lys Ala Cys  Gln Val Cys Ser Ala  Trp Ile Ala 
    1340                 1345                 1350             


Ser Gly  Val Val Ser Asp Leu  Asn Asp Leu Arg Arg  Val His Gln 
    1355                 1360                 1365             


Leu Leu  Val Ser Ser Leu Thr  Lys Ile Gln Ala Gly  Lys Glu Ala 
    1370                 1375                 1380             


Leu Ser  His Leu Tyr Asn Glu  Ser Ala Ser Thr Met  Glu Ile Leu 
    1385                 1390                 1395             


Ala Val  Leu Lys Ala Trp Ala  Glu Val Tyr Ile Ile  Ala Val Gln 
    1400                 1405                 1410             


Arg His  Lys Asn His Arg Gln  Pro Leu Lys Thr Thr  Thr Cys Leu 
    1415                 1420                 1425             


Glu Asp  Gly Ile Arg Asn Gly  Ser Cys Ser Ser Asp  Gly Leu Leu 
    1430                 1435                 1440             


Asp Leu  Val Tyr Ala Asp Leu  Gly Thr Leu Ser Arg  Leu Trp Leu 
    1445                 1450                 1455             


Ala Ala  Leu Gln Asp Phe Ala  Leu Leu Thr Leu Pro  Ser Glu Phe 
    1460                 1465                 1470             


Ala Ser  Gln Leu Pro Ala Glu  Gly Gly Ala Phe Tyr  Thr Ala Glu 
    1475                 1480                 1485             


Thr Ser  Glu Asn Ala Lys Leu  His Tyr Tyr Asn Ser  Trp Ala Leu 
    1490                 1495                 1500             


Ile Leu  His Ala Thr Ala Leu  Trp Leu Thr Ser Thr  Gly Phe Val 
    1505                 1510                 1515             


Val Ala  Asp Pro Asp Glu Gly  Ala Ser Asn Leu Ser  Arg Pro Val 
    1520                 1525                 1530             


Thr Pro  Thr Ser Met Cys Gln  Gly Ser Ser Ser Gly  Ala Thr Ile 
    1535                 1540                 1545             


Lys Ser  Pro Glu Asp Val Tyr  Thr Asp Arg Phe His  Leu Ile Leu 
    1550                 1555                 1560             


Gly Ile  Ser Val Glu Phe Leu  Cys Ser Leu Arg Ser  Asp Ala Thr 
    1565                 1570                 1575             


Met Glu  Ser Ile Thr Ala Cys  Leu His Ala Leu Gln  Ala Leu Leu 
    1580                 1585                 1590             


Asp Val  Pro Trp Pro Arg Ser  Lys Ile Gly Ser Asp  Gln Asp Leu 
    1595                 1600                 1605             


Gly Ile  Glu Leu Leu Asn Val  Leu His Arg Val Ile  Leu Thr Arg 
    1610                 1615                 1620             


Glu Ser  Pro Ser Ile Gln Leu  Ala Ser Leu Glu Val  Val Arg Gln 
    1625                 1630                 1635             


Ile Ile  Cys Ala Ala Gln Glu  His Val Lys Glu Lys  Arg Arg Ser 
    1640                 1645                 1650             


Ala Glu  Val Asp Asp Gly Ala  Ala Glu Lys Glu Thr  Leu Pro Glu 
    1655                 1660                 1665             


Phe Gly  Glu Gly Lys Asp Thr  Gly Gly Leu Val Pro  Gly Lys Ser 
    1670                 1675                 1680             


Leu Val  Phe Ala Thr Leu Glu  Leu Cys Val Cys Ile  Leu Val Arg 
    1685                 1690                 1695             


Gln Leu  Pro Glu Leu Asn Pro  Lys Leu Thr Gly Ser  Pro Gly Val 
    1700                 1705                 1710             


Lys Ala  Thr Lys Pro Gln Ile  Leu Leu Glu Asp Gly  Ser Arg Leu 
    1715                 1720                 1725             


Val Ser  Ala Ala Leu Val Ile  Leu Ser Glu Leu Pro  Ala Val Cys 
    1730                 1735                 1740             


Ser Pro  Glu Gly Ser Ile Ser  Ile Leu Pro Thr Ile  Leu Tyr Leu 
    1745                 1750                 1755             


Thr Ile  Gly Val Leu Arg Glu  Thr Ala Val Lys Leu  Pro Gly Gly 
    1760                 1765                 1770             


Gln Leu  Ser Ser Thr Val Ala  Ala Ser Leu Gln Ala  Leu Lys Gly 
    1775                 1780                 1785             


Ile Leu  Ser Ser Pro Met Ala  Arg Ala Glu Lys Ser  Arg Thr Ala 
    1790                 1795                 1800             


Trp Thr  Asp Leu Leu Arg Ser  Ala Leu Thr Thr Ile  Leu Asp Cys 
    1805                 1810                 1815             


Trp Asp  Pro Val Asp Glu Thr  His Gln Glu Leu Asp  Glu Val Ser 
    1820                 1825                 1830             


Leu Leu  Thr Ala Ile Thr Val  Phe Ile Leu Ser Thr  Ser Pro Glu 
    1835                 1840                 1845             


Val Thr  Thr Ile Pro Cys Leu  Gln Lys Arg Cys Ile  Asp Lys Phe 
    1850                 1855                 1860             


Lys Ala  Thr Leu Glu Ile Lys  Asp Pro Val Val Gln  Ile Lys Thr 
    1865                 1870                 1875             


Tyr Gln  Leu Leu His Ser Ile  Phe Gln Tyr Pro Asn  Pro Ala Val 
    1880                 1885                 1890             


Ser Tyr  Pro Tyr Ile Tyr Ser  Leu Ala Ser Cys Ile  Met Glu Lys 
    1895                 1900                 1905             


Leu Gln  Glu Ile Asp Lys Arg  Lys Pro Glu Asn Thr  Ala Glu Leu 
    1910                 1915                 1920             


Glu Ile  Phe Gln Glu Gly Ile  Lys Val Leu Glu Thr  Leu Val Thr 
    1925                 1930                 1935             


Val Ala  Glu Glu His His Arg  Ala Gln Leu Val Ala  Cys Leu Leu 
    1940                 1945                 1950             


Pro Ile  Leu Ile Ser Phe Leu  Leu Asp Glu Asn Ser  Leu Gly Ser 
    1955                 1960                 1965             


Ala Thr  Ser Ile Met Arg Asn  Leu His Asp Phe Ala  Leu Gln Asn 
    1970                 1975                 1980             


Leu Met  Gln Ile Gly Pro Gln  Tyr Ser Ser Val Phe  Lys Ser Leu 
    1985                 1990                 1995             


Val Ala  Ser Ser Pro Ala Leu  Lys Ala Arg Leu Glu  Ala Ala Ile 
    2000                 2005                 2010             


Lys Gly  Asn Gln Glu Ser Val  Lys Val Lys Ile Pro  Thr Ser Lys 
    2015                 2020                 2025             


Tyr Thr  Lys Ser Pro Gly Lys  Asn Ser Ser Ile Gln  Leu Lys Thr 
    2030                 2035                 2040             


Ser Phe  Leu 
    2045     


<210>  4147
<211>  406
<212>  PRT
<213>  homo sapiens

<400>  4147

Met Ile His Thr Asn Leu Lys Lys Lys Phe Ser Cys Cys Val Leu Val 
1               5                   10                  15      


Phe Leu Leu Phe Ala Val Ile Cys Val Trp Lys Glu Lys Lys Lys Gly 
            20                  25                  30          


Ser Tyr Tyr Asp Ser Phe Lys Leu Gln Thr Lys Glu Phe Gln Val Leu 
        35                  40                  45              


Lys Ser Leu Gly Lys Leu Ala Met Gly Ser Asp Ser Gln Ser Val Ser 
    50                  55                  60                  


Ser Ser Ser Thr Gln Asp Pro His Arg Gly Arg Gln Thr Leu Gly Ser 
65                  70                  75                  80  


Leu Arg Gly Leu Ala Lys Ala Lys Pro Glu Ala Ser Phe Gln Val Trp 
                85                  90                  95      


Asn Lys Asp Ser Ser Ser Lys Asn Leu Ile Pro Arg Leu Gln Lys Ile 
            100                 105                 110         


Trp Lys Asn Tyr Leu Ser Met Asn Lys Tyr Lys Val Ser Tyr Lys Gly 
        115                 120                 125             


Pro Gly Pro Gly Ile Lys Phe Ser Ala Glu Ala Leu Arg Cys His Leu 
    130                 135                 140                 


Arg Asp His Val Asn Val Ser Met Val Glu Val Thr Asp Phe Pro Phe 
145                 150                 155                 160 


Asn Thr Ser Glu Trp Glu Gly Tyr Leu Pro Lys Glu Ser Ile Arg Thr 
                165                 170                 175     


Lys Ala Gly Pro Trp Gly Arg Cys Ala Val Val Ser Ser Ala Gly Ser 
            180                 185                 190         


Leu Lys Ser Ser Gln Leu Gly Arg Glu Ile Asp Asp His Asp Ala Val 
        195                 200                 205             


Leu Arg Phe Asn Gly Ala Pro Thr Ala Asn Phe Gln Gln Asp Val Gly 
    210                 215                 220                 


Thr Lys Thr Thr Ile Arg Leu Met Asn Ser Gln Leu Val Thr Thr Glu 
225                 230                 235                 240 


Lys Arg Phe Leu Lys Asp Ser Leu Tyr Asn Glu Gly Ile Leu Ile Val 
                245                 250                 255     


Trp Asp Pro Ser Val Tyr His Ser Asp Ile Pro Lys Trp Tyr Gln Asn 
            260                 265                 270         


Pro Asp Tyr Asn Phe Phe Asn Asn Tyr Lys Thr Tyr Arg Lys Leu His 
        275                 280                 285             


Pro Asn Gln Pro Phe Tyr Ile Leu Lys Pro Gln Met Pro Trp Glu Leu 
    290                 295                 300                 


Trp Asp Ile Leu Gln Glu Ile Ser Pro Glu Glu Ile Gln Pro Asn Pro 
305                 310                 315                 320 


Pro Ser Ser Gly Met Leu Gly Ile Ile Ile Met Met Thr Leu Cys Asp 
                325                 330                 335     


Gln Val Asp Ile Tyr Glu Phe Leu Pro Ser Lys Arg Lys Thr Asp Val 
            340                 345                 350         


Cys Tyr Tyr Tyr Gln Lys Phe Phe Asp Ser Ala Cys Thr Met Gly Ala 
        355                 360                 365             


Tyr His Pro Leu Leu Tyr Glu Lys Asn Leu Val Lys His Leu Asn Gln 
    370                 375                 380                 


Gly Thr Asp Glu Asp Ile Tyr Leu Leu Gly Lys Ala Thr Leu Pro Gly 
385                 390                 395                 400 


Phe Arg Thr Ile His Cys 
                405     


<210>  4148
<211>  387
<212>  PRT
<213>  homo sapiens

<400>  4148

Met Thr Met Glu Gly Ala Ser Gly Ser Ser Phe Gly Ile Asp Thr Ile 
1               5                   10                  15      


Leu Ser Ser Ala Ser Ser Gly Ser Pro Gly Met Met Asn Gly Asp Phe 
            20                  25                  30          


Arg Pro Leu Gly Glu Ala Arg Thr Ala Asp Phe Arg Ser Gln Ala Thr 
        35                  40                  45              


Pro Ser Pro Cys Ser Glu Ile Asp Thr Val Gly Thr Ala Pro Ser Ser 
    50                  55                  60                  


Pro Ile Ser Val Thr Met Glu Pro Pro Glu Pro His Leu Val Ala Asp 
65                  70                  75                  80  


Ala Thr Gln His His His His Leu His His Ser Gln Gln Pro Pro Pro 
                85                  90                  95      


Pro Ala Ala Ala Pro Thr Gln Ser Leu Gln Pro Leu Pro Gln Gln Gln 
            100                 105                 110         


Gln Pro Leu Pro Pro Gln Gln Pro Pro Pro Pro Pro Pro Gln Gln Leu 
        115                 120                 125             


Gly Ser Ala Ala Ser Ala Pro Arg Thr Ser Thr Ser Ser Phe Leu Ile 
    130                 135                 140                 


Lys Asp Ile Leu Gly Asp Ser Lys Pro Leu Ala Ala Cys Ala Pro Tyr 
145                 150                 155                 160 


Ser Thr Ser Val Ser Ser Pro His His Thr Pro Lys Gln Glu Ser Asn 
                165                 170                 175     


Ala Val His Glu Ser Phe Arg Pro Lys Leu Glu Gln Glu Asp Ser Lys 
            180                 185                 190         


Thr Lys Leu Asp Lys Arg Glu Asp Ser Gln Ser Asp Ile Lys Cys His 
        195                 200                 205             


Gly Thr Lys Glu Glu Gly Asp Arg Glu Ile Thr Ser Ser Arg Glu Ser 
    210                 215                 220                 


Pro Pro Val Arg Ala Lys Lys Pro Arg Lys Ala Arg Thr Ala Phe Ser 
225                 230                 235                 240 


Asp His Gln Leu Asn Gln Leu Glu Arg Ser Phe Glu Arg Gln Lys Tyr 
                245                 250                 255     


Leu Ser Val Gln Asp Arg Met Asp Leu Ala Ala Ala Leu Asn Leu Thr 
            260                 265                 270         


Asp Thr Gln Val Lys Thr Trp Tyr Gln Asn Arg Arg Thr Lys Trp Lys 
        275                 280                 285             


Arg Gln Thr Ala Val Gly Leu Glu Leu Leu Ala Glu Ala Gly Asn Tyr 
    290                 295                 300                 


Ser Ala Leu Gln Arg Met Phe Pro Ser Pro Tyr Phe Tyr His Pro Ser 
305                 310                 315                 320 


Leu Leu Gly Ser Met Asp Ser Thr Thr Ala Ala Ala Ala Ala Ala Ala 
                325                 330                 335     


Met Tyr Ser Ser Met Tyr Arg Thr Pro Pro Ala Pro His Pro Gln Leu 
            340                 345                 350         


Gln Arg Pro Leu Val Pro Arg Val Leu Ile His Gly Leu Gly Pro Gly 
        355                 360                 365             


Gly Gln Pro Ala Leu Asn Pro Leu Ser Ser Pro Ile Pro Gly Thr Pro 
    370                 375                 380                 


His Pro Arg 
385         


<210>  4149
<211>  632
<212>  PRT
<213>  homo sapiens

<400>  4149

Met Asp Thr Met Met Leu Asn Val Arg Asn Leu Phe Glu Gln Leu Val 
1               5                   10                  15      


Arg Arg Val Glu Ile Leu Ser Glu Gly Asn Glu Val Gln Phe Ile Gln 
            20                  25                  30          


Leu Ala Lys Asp Phe Glu Asp Phe Arg Lys Lys Trp Gln Arg Thr Asp 
        35                  40                  45              


His Glu Leu Gly Lys Tyr Lys Asp Leu Leu Met Lys Ala Glu Thr Glu 
    50                  55                  60                  


Arg Ser Ala Leu Asp Val Lys Leu Lys His Ala Arg Asn Gln Val Asp 
65                  70                  75                  80  


Val Glu Ile Lys Arg Arg Gln Arg Ala Glu Ala Asp Cys Glu Lys Leu 
                85                  90                  95      


Glu Arg Gln Ile Gln Leu Ile Arg Glu Met Leu Met Cys Asp Thr Ser 
            100                 105                 110         


Gly Ser Ile Gln Leu Ser Glu Glu Gln Lys Ser Ala Leu Ala Phe Leu 
        115                 120                 125             


Asn Arg Gly Gln Pro Ser Ser Ser Asn Ala Gly Asn Lys Arg Leu Ser 
    130                 135                 140                 


Thr Ile Asp Glu Ser Gly Ser Ile Leu Ser Asp Ile Ser Phe Asp Lys 
145                 150                 155                 160 


Thr Asp Glu Ser Leu Asp Trp Asp Ser Ser Leu Val Lys Thr Phe Lys 
                165                 170                 175     


Leu Lys Lys Arg Glu Lys Arg Arg Ser Thr Ser Arg Gln Phe Val Asp 
            180                 185                 190         


Gly Pro Pro Gly Pro Val Lys Lys Thr Arg Ser Ile Gly Ser Ala Val 
        195                 200                 205             


Asp Gln Gly Asn Glu Ser Ile Val Ala Lys Thr Thr Val Thr Val Pro 
    210                 215                 220                 


Asn Asp Gly Gly Pro Ile Glu Ala Val Ser Thr Ile Glu Thr Val Pro 
225                 230                 235                 240 


Tyr Trp Thr Arg Ser Arg Arg Lys Thr Gly Thr Leu Gln Pro Trp Asn 
                245                 250                 255     


Ser Asp Ser Thr Leu Asn Ser Arg Gln Leu Glu Pro Arg Thr Glu Thr 
            260                 265                 270         


Asp Ser Val Gly Thr Pro Gln Ser Asn Gly Gly Met Arg Leu His Asp 
        275                 280                 285             


Phe Val Ser Lys Thr Val Ile Lys Pro Glu Ser Cys Val Pro Cys Gly 
    290                 295                 300                 


Lys Arg Ile Lys Phe Gly Lys Leu Ser Leu Lys Cys Arg Asp Cys Arg 
305                 310                 315                 320 


Val Val Ser His Pro Glu Cys Arg Asp Arg Cys Pro Leu Pro Cys Ile 
                325                 330                 335     


Pro Thr Leu Ile Gly Thr Pro Val Lys Ile Gly Glu Gly Met Leu Ala 
            340                 345                 350         


Asp Phe Val Ser Gln Thr Ser Pro Met Ile Pro Ser Ile Val Val His 
        355                 360                 365             


Cys Val Asn Glu Ile Glu Gln Arg Gly Leu Thr Glu Thr Gly Leu Tyr 
    370                 375                 380                 


Arg Ile Ser Gly Cys Asp Arg Thr Val Lys Glu Leu Lys Glu Lys Phe 
385                 390                 395                 400 


Leu Arg Val Lys Thr Val Pro Leu Leu Ser Lys Val Asp Asp Ile His 
                405                 410                 415     


Ala Ile Cys Ser Leu Leu Lys Asp Phe Leu Arg Asn Leu Lys Glu Pro 
            420                 425                 430         


Leu Leu Thr Phe Arg Leu Asn Arg Ala Phe Met Glu Ala Ala Glu Ile 
        435                 440                 445             


Thr Asp Glu Asp Asn Ser Ile Ala Ala Met Tyr Gln Ala Val Gly Glu 
    450                 455                 460                 


Leu Pro Gln Ala Asn Arg Asp Thr Leu Ala Phe Leu Met Ile His Leu 
465                 470                 475                 480 


Gln Arg Val Ala Gln Ser Pro His Thr Lys Met Asp Val Ala Asn Leu 
                485                 490                 495     


Ala Lys Val Phe Gly Pro Thr Ile Val Ala His Ala Val Pro Asn Pro 
            500                 505                 510         


Asp Pro Val Thr Met Leu Gln Asp Ile Lys Arg Gln Pro Lys Val Val 
        515                 520                 525             


Glu Arg Leu Leu Ser Leu Pro Leu Glu Tyr Trp Ser Gln Phe Met Met 
    530                 535                 540                 


Val Glu Gln Glu Asn Ile Asp Pro Leu His Val Ile Glu Asn Ser Asn 
545                 550                 555                 560 


Ala Phe Ser Thr Pro Gln Thr Pro Asp Ile Lys Val Ser Leu Leu Gly 
                565                 570                 575     


Pro Val Thr Thr Pro Glu His Gln Leu Leu Lys Thr Pro Ser Ser Ser 
            580                 585                 590         


Ser Leu Ser Gln Arg Val Arg Ser Thr Leu Thr Lys Asn Thr Pro Arg 
        595                 600                 605             


Phe Gly Ser Lys Ser Lys Ser Ala Thr Asn Leu Gly Arg Gln Gly Asn 
    610                 615                 620                 


Phe Phe Ala Ser Pro Met Leu Lys 
625                 630         


<210>  4150
<211>  1207
<212>  PRT
<213>  homo sapiens

<400>  4150

Met Leu Leu Thr Leu Ile Ile Leu Leu Pro Val Val Ser Lys Phe Ser 
1               5                   10                  15      


Phe Val Ser Leu Ser Ala Pro Gln His Trp Ser Cys Pro Glu Gly Thr 
            20                  25                  30          


Leu Ala Gly Asn Gly Asn Ser Thr Cys Val Gly Pro Ala Pro Phe Leu 
        35                  40                  45              


Ile Phe Ser His Gly Asn Ser Ile Phe Arg Ile Asp Thr Glu Gly Thr 
    50                  55                  60                  


Asn Tyr Glu Gln Leu Val Val Asp Ala Gly Val Ser Val Ile Met Asp 
65                  70                  75                  80  


Phe His Tyr Asn Glu Lys Arg Ile Tyr Trp Val Asp Leu Glu Arg Gln 
                85                  90                  95      


Leu Leu Gln Arg Val Phe Leu Asn Gly Ser Arg Gln Glu Arg Val Cys 
            100                 105                 110         


Asn Ile Glu Lys Asn Val Ser Gly Met Ala Ile Asn Trp Ile Asn Glu 
        115                 120                 125             


Glu Val Ile Trp Ser Asn Gln Gln Glu Gly Ile Ile Thr Val Thr Asp 
    130                 135                 140                 


Met Lys Gly Asn Asn Ser His Ile Leu Leu Ser Ala Leu Lys Tyr Pro 
145                 150                 155                 160 


Ala Asn Val Ala Val Asp Pro Val Glu Arg Phe Ile Phe Trp Ser Ser 
                165                 170                 175     


Glu Val Ala Gly Ser Leu Tyr Arg Ala Asp Leu Asp Gly Val Gly Val 
            180                 185                 190         


Lys Ala Leu Leu Glu Thr Ser Glu Lys Ile Thr Ala Val Ser Leu Asp 
        195                 200                 205             


Val Leu Asp Lys Arg Leu Phe Trp Ile Gln Tyr Asn Arg Glu Gly Ser 
    210                 215                 220                 


Asn Ser Leu Ile Cys Ser Cys Asp Tyr Asp Gly Gly Ser Val His Ile 
225                 230                 235                 240 


Ser Lys His Pro Thr Gln His Asn Leu Phe Ala Met Ser Leu Phe Gly 
                245                 250                 255     


Asp Arg Ile Phe Tyr Ser Thr Trp Lys Met Lys Thr Ile Trp Ile Ala 
            260                 265                 270         


Asn Lys His Thr Gly Lys Asp Met Val Arg Ile Asn Leu His Ser Ser 
        275                 280                 285             


Phe Val Pro Leu Gly Glu Leu Lys Val Val His Pro Leu Ala Gln Pro 
    290                 295                 300                 


Lys Ala Glu Asp Asp Thr Trp Glu Pro Glu Gln Lys Leu Cys Lys Leu 
305                 310                 315                 320 


Arg Lys Gly Asn Cys Ser Ser Thr Val Cys Gly Gln Asp Leu Gln Ser 
                325                 330                 335     


His Leu Cys Met Cys Ala Glu Gly Tyr Ala Leu Ser Arg Asp Arg Lys 
            340                 345                 350         


Tyr Cys Glu Asp Val Asn Glu Cys Ala Phe Trp Asn His Gly Cys Thr 
        355                 360                 365             


Leu Gly Cys Lys Asn Thr Pro Gly Ser Tyr Tyr Cys Thr Cys Pro Val 
    370                 375                 380                 


Gly Phe Val Leu Leu Pro Asp Gly Lys Arg Cys His Gln Leu Val Ser 
385                 390                 395                 400 


Cys Pro Arg Asn Val Ser Glu Cys Ser His Asp Cys Val Leu Thr Ser 
                405                 410                 415     


Glu Gly Pro Leu Cys Phe Cys Pro Glu Gly Ser Val Leu Glu Arg Asp 
            420                 425                 430         


Gly Lys Thr Cys Ser Gly Cys Ser Ser Pro Asp Asn Gly Gly Cys Ser 
        435                 440                 445             


Gln Leu Cys Val Pro Leu Ser Pro Val Ser Trp Glu Cys Asp Cys Phe 
    450                 455                 460                 


Pro Gly Tyr Asp Leu Gln Leu Asp Glu Lys Ser Cys Ala Ala Ser Gly 
465                 470                 475                 480 


Pro Gln Pro Phe Leu Leu Phe Ala Asn Ser Gln Asp Ile Arg His Met 
                485                 490                 495     


His Phe Asp Gly Thr Asp Tyr Gly Thr Leu Leu Ser Gln Gln Met Gly 
            500                 505                 510         


Met Val Tyr Ala Leu Asp His Asp Pro Val Glu Asn Lys Ile Tyr Phe 
        515                 520                 525             


Ala His Thr Ala Leu Lys Trp Ile Glu Arg Ala Asn Met Asp Gly Ser 
    530                 535                 540                 


Gln Arg Glu Arg Leu Ile Glu Glu Gly Val Asp Val Pro Glu Gly Leu 
545                 550                 555                 560 


Ala Val Asp Trp Ile Gly Arg Arg Phe Tyr Trp Thr Asp Arg Gly Lys 
                565                 570                 575     


Ser Leu Ile Gly Arg Ser Asp Leu Asn Gly Lys Arg Ser Lys Ile Ile 
            580                 585                 590         


Thr Lys Glu Asn Ile Ser Gln Pro Arg Gly Ile Ala Val His Pro Met 
        595                 600                 605             


Ala Lys Arg Leu Phe Trp Thr Asp Thr Gly Ile Asn Pro Arg Ile Glu 
    610                 615                 620                 


Ser Ser Ser Leu Gln Gly Leu Gly Arg Leu Val Ile Ala Ser Ser Asp 
625                 630                 635                 640 


Leu Ile Trp Pro Ser Gly Ile Thr Ile Asp Phe Leu Thr Asp Lys Leu 
                645                 650                 655     


Tyr Trp Cys Asp Ala Lys Gln Ser Val Ile Glu Met Ala Asn Leu Asp 
            660                 665                 670         


Gly Ser Lys Arg Arg Arg Leu Thr Gln Asn Asp Val Gly His Pro Phe 
        675                 680                 685             


Ala Val Ala Val Phe Glu Asp Tyr Val Trp Phe Ser Asp Trp Ala Met 
    690                 695                 700                 


Pro Ser Val Met Arg Val Asn Lys Arg Thr Gly Lys Asp Arg Val Arg 
705                 710                 715                 720 


Leu Gln Gly Ser Met Leu Lys Pro Ser Ser Leu Val Val Val His Pro 
                725                 730                 735     


Leu Ala Lys Pro Gly Ala Asp Pro Cys Leu Tyr Gln Asn Gly Gly Cys 
            740                 745                 750         


Glu His Ile Cys Lys Lys Arg Leu Gly Thr Ala Trp Cys Ser Cys Arg 
        755                 760                 765             


Glu Gly Phe Met Lys Ala Ser Asp Gly Lys Thr Cys Leu Ala Leu Asp 
    770                 775                 780                 


Gly His Gln Leu Leu Ala Gly Gly Glu Val Asp Leu Lys Asn Gln Val 
785                 790                 795                 800 


Thr Pro Leu Asp Ile Leu Ser Lys Thr Arg Val Ser Glu Asp Asn Ile 
                805                 810                 815     


Thr Glu Ser Gln His Met Leu Val Ala Glu Ile Met Val Ser Asp Gln 
            820                 825                 830         


Asp Asp Cys Ala Pro Val Gly Cys Ser Met Tyr Ala Arg Cys Ile Ser 
        835                 840                 845             


Glu Gly Glu Asp Ala Thr Cys Gln Cys Leu Lys Gly Phe Ala Gly Asp 
    850                 855                 860                 


Gly Lys Leu Cys Ser Asp Ile Asp Glu Cys Glu Met Gly Val Pro Val 
865                 870                 875                 880 


Cys Pro Pro Ala Ser Ser Lys Cys Ile Asn Thr Glu Gly Gly Tyr Val 
                885                 890                 895     


Cys Arg Cys Ser Glu Gly Tyr Gln Gly Asp Gly Ile His Cys Leu Asp 
            900                 905                 910         


Ile Asp Glu Cys Gln Leu Gly Glu His Ser Cys Gly Glu Asn Ala Ser 
        915                 920                 925             


Cys Thr Asn Thr Glu Gly Gly Tyr Thr Cys Met Cys Ala Gly Arg Leu 
    930                 935                 940                 


Ser Glu Pro Gly Leu Ile Cys Pro Asp Ser Thr Pro Pro Pro His Leu 
945                 950                 955                 960 


Arg Glu Asp Asp His His Tyr Ser Val Arg Asn Ser Asp Ser Glu Cys 
                965                 970                 975     


Pro Leu Ser His Asp Gly Tyr Cys Leu His Asp Gly Val Cys Met Tyr 
            980                 985                 990         


Ile Glu Ala Leu Asp Lys Tyr Ala  Cys Asn Cys Val Val  Gly Tyr Ile 
        995                 1000                 1005             


Gly Glu  Arg Cys Gln Tyr Arg  Asp Leu Lys Trp Trp  Glu Leu Arg 
    1010                 1015                 1020             


His Ala  Gly His Gly Gln Gln  Gln Lys Val Ile Val  Val Ala Val 
    1025                 1030                 1035             


Cys Val  Val Val Leu Val Met  Leu Leu Leu Leu Ser  Leu Trp Gly 
    1040                 1045                 1050             


Ala His  Tyr Tyr Arg Thr Gln  Lys Leu Leu Ser Lys  Asn Pro Lys 
    1055                 1060                 1065             


Asn Pro  Tyr Glu Glu Ser Ser  Arg Asp Val Arg Ser  Arg Arg Pro 
    1070                 1075                 1080             


Ala Asp  Thr Glu Asp Gly Met  Ser Ser Cys Pro Gln  Pro Trp Phe 
    1085                 1090                 1095             


Val Val  Ile Lys Glu His Gln  Asp Leu Lys Asn Gly  Gly Gln Pro 
    1100                 1105                 1110             


Val Ala  Gly Glu Asp Gly Gln  Ala Ala Asp Gly Ser  Met Gln Pro 
    1115                 1120                 1125             


Thr Ser  Trp Arg Gln Glu Pro  Gln Leu Cys Gly Met  Gly Thr Glu 
    1130                 1135                 1140             


Gln Gly  Cys Trp Ile Pro Val  Ser Ser Asp Lys Gly  Ser Cys Pro 
    1145                 1150                 1155             


Gln Val  Met Glu Arg Ser Phe  His Met Pro Ser Tyr  Gly Thr Gln 
    1160                 1165                 1170             


Thr Leu  Glu Gly Gly Val Glu  Lys Pro His Ser Leu  Leu Ser Ala 
    1175                 1180                 1185             


Asn Pro  Leu Trp Gln Gln Arg  Ala Leu Asp Pro Pro  His Gln Met 
    1190                 1195                 1200             


Glu Leu  Thr Gln 
    1205         


<210>  4151
<211>  3703
<212>  PRT
<213>  homo sapiens

<400>  4151

Met Glu Gly Cys Asp Ser Pro Val Val Ser Gly Lys Asp Asn Gly Cys 
1               5                   10                  15      


Gly Ile Pro Gln His Gln Gln Trp Thr Glu Leu Asn Ser Thr His Leu 
            20                  25                  30          


Pro Asp Lys Pro Ser Ser Met Glu Gln Ser Thr Gly Glu Ser His Gly 
        35                  40                  45              


Pro Leu Asp Ser Leu Arg Ala Pro Phe Asn Glu Arg Leu Ala Glu Ser 
    50                  55                  60                  


Thr Ala Ser Ala Gly Pro Pro Ser Glu Pro Ala Ser Lys Glu Val Thr 
65                  70                  75                  80  


Cys Asn Glu Cys Ser Ala Ser Phe Ala Ser Leu Gln Thr Tyr Met Glu 
                85                  90                  95      


His His Cys Pro Ser Ala Arg Pro Pro Pro Pro Leu Arg Glu Glu Ser 
            100                 105                 110         


Ala Ser Asp Thr Gly Glu Glu Gly Asp Glu Glu Ser Asp Val Glu Asn 
        115                 120                 125             


Leu Ala Gly Glu Ile Val Tyr Gln Pro Asp Gly Ser Ala Tyr Ile Val 
    130                 135                 140                 


Glu Ser Leu Ser Gln Leu Thr Gln Gly Gly Gly Ala Cys Gly Ser Gly 
145                 150                 155                 160 


Ser Gly Ser Gly Pro Leu Pro Ser Leu Phe Leu Asn Ser Leu Pro Gly 
                165                 170                 175     


Ala Gly Gly Lys Gln Gly Asp Pro Ser Cys Ala Ala Pro Val Tyr Pro 
            180                 185                 190         


Gln Ile Ile Asn Thr Phe His Ile Ala Ser Ser Phe Gly Lys Trp Phe 
        195                 200                 205             


Glu Gly Pro Asp Gln Ala Phe Pro Asn Thr Ser Ala Leu Ala Gly Leu 
    210                 215                 220                 


Ser Pro Val Leu His Ser Phe Arg Val Phe Asp Val Arg His Lys Ser 
225                 230                 235                 240 


Asn Lys Asp Tyr Leu Asn Ser Asp Gly Ser Ala Lys Ser Ser Cys Val 
                245                 250                 255     


Ser Lys Asp Val Pro Asn Asn Val Asp Leu Ser Lys Phe Asp Gly Phe 
            260                 265                 270         


Val Leu Tyr Gly Lys Arg Lys Pro Ile Leu Met Cys Phe Leu Cys Lys 
        275                 280                 285             


Leu Ser Phe Gly Tyr Val Arg Ser Phe Val Thr His Ala Val His Asp 
    290                 295                 300                 


His Arg Met Thr Leu Ser Glu Asp Glu Arg Lys Ile Leu Ser Asn Lys 
305                 310                 315                 320 


Asn Ile Ser Ala Ile Ile Gln Gly Ile Gly Lys Asp Lys Glu Pro Leu 
                325                 330                 335     


Val Ser Phe Leu Glu Pro Lys Asn Lys Asn Phe Gln His Pro Leu Val 
            340                 345                 350         


Ser Thr Ala Asn Leu Ile Gly Pro Gly His Ser Phe Tyr Gly Lys Phe 
        355                 360                 365             


Ser Gly Ile Arg Met Glu Gly Glu Glu Ala Leu Pro Ala Gly Ser Ala 
    370                 375                 380                 


Ala Gly Pro Glu Gln Pro Gln Ala Gly Leu Leu Thr Pro Ser Thr Leu 
385                 390                 395                 400 


Leu Asn Leu Gly Gly Leu Thr Ser Ser Val Leu Lys Thr Pro Ile Thr 
                405                 410                 415     


Ser Val Pro Leu Gly Pro Leu Ala Ser Ser Pro Thr Lys Ser Ser Glu 
            420                 425                 430         


Gly Lys Asp Ser Gly Ala Ala Glu Gly Glu Lys Gln Glu Val Gly Asp 
        435                 440                 445             


Gly Asp Cys Phe Ser Glu Lys Val Glu Pro Ala Glu Glu Glu Ala Glu 
    450                 455                 460                 


Glu Glu Glu Glu Glu Glu Glu Ala Glu Glu Glu Glu Glu Glu Glu Glu 
465                 470                 475                 480 


Glu Glu Glu Glu Glu Glu Glu Asp Glu Gly Cys Lys Gly Leu Phe Pro 
                485                 490                 495     


Ser Glu Leu Asp Glu Glu Leu Glu Asp Arg Pro His Glu Glu Pro Gly 
            500                 505                 510         


Ala Ala Ala Gly Ser Ser Ser Lys Lys Asp Leu Ala Leu Ser Asn Gln 
        515                 520                 525             


Ser Ile Ser Asn Ser Pro Leu Met Pro Asn Val Leu Gln Thr Leu Ser 
    530                 535                 540                 


Arg Gly Thr Ala Ser Thr Ser Ser Asn Ser Ala Ser Ser Phe Val Val 
545                 550                 555                 560 


Phe Asp Gly Ala Asn Arg Arg Asn Arg Leu Ser Phe Asn Ser Glu Gly 
                565                 570                 575     


Val Arg Ala Asn Val Ala Glu Gly Gly Arg Arg Leu Asp Phe Ala Asp 
            580                 585                 590         


Glu Ser Ala Asn Lys Asp Asn Ala Thr Ala Pro Glu Pro Asn Glu Ser 
        595                 600                 605             


Thr Glu Gly Asp Asp Gly Gly Phe Val Pro His His Gln His Ala Gly 
    610                 615                 620                 


Ser Leu Cys Glu Leu Gly Val Gly Glu Cys Pro Ser Gly Ser Gly Val 
625                 630                 635                 640 


Glu Cys Pro Lys Cys Asp Thr Val Leu Gly Ser Ser Arg Ser Leu Gly 
                645                 650                 655     


Gly His Met Thr Met Met His Ser Arg Asn Ser Cys Lys Thr Leu Lys 
            660                 665                 670         


Cys Pro Lys Cys Asn Trp His Tyr Lys Tyr Gln Gln Thr Leu Glu Ala 
        675                 680                 685             


His Met Lys Glu Lys His Pro Glu Pro Gly Gly Ser Cys Val Tyr Cys 
    690                 695                 700                 


Lys Ser Gly Gln Pro His Pro Arg Leu Ala Arg Gly Glu Ser Tyr Thr 
705                 710                 715                 720 


Cys Gly Tyr Lys Pro Phe Arg Cys Glu Val Cys Asn Tyr Ser Thr Thr 
                725                 730                 735     


Thr Lys Gly Asn Leu Ser Ile His Met Gln Ser Asp Lys His Leu Asn 
            740                 745                 750         


Asn Met Gln Asn Leu Gln Asn Gly Gly Gly Glu Gln Val Phe Ser His 
        755                 760                 765             


Thr Ala Gly Ala Ala Ala Ala Ala Val Ala Ala Ala Ala Ala Ala Ala 
    770                 775                 780                 


Asn Ile Ser Ser Ser Cys Gly Ala Pro Ser Pro Thr Lys Pro Lys Thr 
785                 790                 795                 800 


Lys Pro Thr Trp Arg Cys Glu Val Cys Asp Tyr Glu Thr Asn Val Ala 
                805                 810                 815     


Arg Asn Leu Arg Ile His Met Thr Ser Glu Lys His Met His Asn Met 
            820                 825                 830         


Met Leu Leu Gln Gln Asn Met Thr Gln Ile Gln His Asn Arg His Leu 
        835                 840                 845             


Gly Leu Gly Ser Leu Pro Ser Pro Ala Glu Ala Glu Leu Tyr Gln Tyr 
    850                 855                 860                 


Tyr Leu Ala Gln Asn Met Asn Leu Pro Asn Leu Lys Met Asp Ser Ala 
865                 870                 875                 880 


Ala Ser Asp Ala Gln Phe Met Met Ser Gly Phe Gln Leu Asp Pro Ala 
                885                 890                 895     


Gly Pro Met Ala Ala Met Thr Pro Ala Leu Val Gly Gly Glu Ile Pro 
            900                 905                 910         


Leu Asp Met Arg Leu Gly Gly Gly Gln Leu Val Ser Glu Glu Leu Met 
        915                 920                 925             


Asn Leu Gly Glu Ser Phe Ile Gln Thr Asn Asp Pro Ser Leu Lys Leu 
    930                 935                 940                 


Phe Gln Cys Ala Val Cys Asn Lys Phe Thr Thr Asp Asn Leu Asp Met 
945                 950                 955                 960 


Leu Gly Leu His Met Asn Val Glu Arg Ser Leu Ser Glu Asp Glu Trp 
                965                 970                 975     


Lys Ala Val Met Gly Asp Ser Tyr Gln Cys Lys Leu Cys Arg Tyr Asn 
            980                 985                 990         


Thr Gln Leu Lys Ala Asn Phe Gln  Leu His Cys Lys Thr  Asp Lys His 
        995                 1000                 1005             


Val Gln  Lys Tyr Gln Leu Val  Ala His Ile Lys Glu  Gly Gly Lys 
    1010                 1015                 1020             


Ala Asn  Glu Trp Arg Leu Lys  Cys Val Ala Ile Gly  Asn Pro Val 
    1025                 1030                 1035             


His Leu  Lys Cys Asn Ala Cys  Asp Tyr Tyr Thr Asn  Ser Leu Glu 
    1040                 1045                 1050             


Lys Leu  Arg Leu His Thr Val  Asn Ser Arg His Glu  Ala Ser Leu 
    1055                 1060                 1065             


Lys Leu  Tyr Lys His Leu Gln  Gln His Glu Ser Gly  Val Glu Gly 
    1070                 1075                 1080             


Glu Ser  Cys Tyr Tyr His Cys  Val Leu Cys Asn Tyr  Ser Thr Lys 
    1085                 1090                 1095             


Ala Lys  Leu Asn Leu Ile Gln  His Val Arg Ser Met  Lys His Gln 
    1100                 1105                 1110             


Arg Ser  Glu Ser Leu Arg Lys  Leu Gln Arg Leu Gln  Lys Gly Leu 
    1115                 1120                 1125             


Pro Glu  Glu Asp Glu Asp Leu  Gly Gln Ile Phe Thr  Ile Arg Arg 
    1130                 1135                 1140             


Cys Pro  Ser Thr Asp Pro Glu  Glu Ala Ile Glu Asp  Val Glu Gly 
    1145                 1150                 1155             


Pro Ser  Glu Thr Ala Ala Asp  Pro Glu Glu Leu Ala  Lys Asp Gln 
    1160                 1165                 1170             


Glu Gly  Gly Ala Ser Ser Ser  Gln Ala Glu Lys Glu  Leu Thr Asp 
    1175                 1180                 1185             


Ser Pro  Ala Thr Ser Lys Arg  Ile Ser Phe Pro Gly  Ser Ser Glu 
    1190                 1195                 1200             


Ser Pro  Leu Ser Ser Lys Arg  Pro Lys Thr Ala Glu  Glu Ile Lys 
    1205                 1210                 1215             


Pro Glu  Gln Met Tyr Gln Cys  Pro Tyr Cys Lys Tyr  Ser Asn Ala 
    1220                 1225                 1230             


Asp Val  Asn Arg Leu Arg Val  His Ala Met Thr Gln  His Ser Val 
    1235                 1240                 1245             


Gln Pro  Met Leu Arg Cys Pro  Leu Cys Gln Asp Met  Leu Asn Asn 
    1250                 1255                 1260             


Lys Ile  His Leu Gln Leu His  Leu Thr His Leu His  Ser Val Ala 
    1265                 1270                 1275             


Pro Asp  Cys Val Glu Lys Leu  Ile Met Thr Val Thr  Thr Pro Glu 
    1280                 1285                 1290             


Met Val  Met Pro Ser Ser Met  Phe Leu Pro Ala Ala  Val Pro Asp 
    1295                 1300                 1305             


Arg Asp  Gly Asn Ser Asn Leu  Glu Glu Ala Gly Lys  Gln Pro Glu 
    1310                 1315                 1320             


Thr Ser  Glu Asp Leu Gly Lys  Asn Ile Leu Pro Ser  Ala Ser Thr 
    1325                 1330                 1335             


Glu Gln  Ser Gly Asp Leu Lys  Pro Ser Pro Ala Asp  Pro Gly Ser 
    1340                 1345                 1350             


Val Arg  Glu Asp Ser Gly Phe  Ile Cys Trp Lys Lys  Gly Cys Asn 
    1355                 1360                 1365             


Gln Val  Phe Lys Thr Ser Ala  Ala Leu Gln Thr His  Phe Asn Glu 
    1370                 1375                 1380             


Val His  Ala Lys Arg Pro Gln  Leu Pro Val Ser Asp  Arg His Val 
    1385                 1390                 1395             


Tyr Lys  Tyr Arg Cys Asn Gln  Cys Ser Leu Ala Phe  Lys Thr Ile 
    1400                 1405                 1410             


Glu Lys  Leu Gln Leu His Ser  Gln Tyr His Val Ile  Arg Ala Ala 
    1415                 1420                 1425             


Thr Met  Cys Cys Leu Cys Gln  Arg Ser Phe Arg Thr  Phe Gln Ala 
    1430                 1435                 1440             


Leu Lys  Lys His Leu Glu Thr  Ser His Leu Glu Leu  Ser Glu Ala 
    1445                 1450                 1455             


Asp Ile  Gln Gln Leu Tyr Gly  Gly Leu Leu Ala Asn  Gly Asp Leu 
    1460                 1465                 1470             


Leu Ala  Met Gly Asp Pro Thr  Leu Ala Glu Asp His  Thr Ile Ile 
    1475                 1480                 1485             


Val Glu  Glu Asp Lys Glu Glu  Glu Ser Asp Leu Glu  Asp Lys Gln 
    1490                 1495                 1500             


Ser Pro  Thr Gly Ser Asp Ser  Gly Ser Val Gln Glu  Asp Ser Gly 
    1505                 1510                 1515             


Ser Glu  Pro Lys Arg Ala Leu  Pro Phe Arg Lys Gly  Pro Asn Phe 
    1520                 1525                 1530             


Thr Met  Glu Lys Phe Leu Asp  Pro Ser Arg Pro Tyr  Lys Cys Thr 
    1535                 1540                 1545             


Val Cys  Lys Glu Ser Phe Thr  Gln Lys Asn Ile Leu  Leu Val His 
    1550                 1555                 1560             


Tyr Asn  Ser Val Ser His Leu  His Lys Leu Lys Arg  Ala Leu Gln 
    1565                 1570                 1575             


Glu Ser  Ala Thr Gly Gln Pro  Glu Pro Thr Ser Ser  Pro Asp Asn 
    1580                 1585                 1590             


Lys Pro  Phe Lys Cys Asn Thr  Cys Asn Val Ala Tyr  Ser Gln Ser 
    1595                 1600                 1605             


Ser Thr  Leu Glu Ile His Met  Arg Ser Val Leu His  Gln Thr Lys 
    1610                 1615                 1620             


Ala Arg  Ala Ala Lys Leu Glu  Ala Ala Ser Gly Ser  Ser Asn Gly 
    1625                 1630                 1635             


Thr Gly  Asn Ser Ser Ser Ile  Ser Leu Ser Ser Ser  Thr Pro Ser 
    1640                 1645                 1650             


Pro Val  Ser Thr Ser Gly Ser  Asn Thr Phe Thr Thr  Ser Asn Pro 
    1655                 1660                 1665             


Ser Ser  Ala Gly Ile Ala Pro  Ser Ser Asn Leu Leu  Ser Gln Val 
    1670                 1675                 1680             


Pro Thr  Glu Ser Val Gly Met  Pro Pro Leu Gly Asn  Pro Ile Gly 
    1685                 1690                 1695             


Ala Asn  Ile Ala Ser Pro Ser  Glu Pro Lys Glu Ala  Asn Arg Lys 
    1700                 1705                 1710             


Lys Leu  Ala Asp Met Ile Ala  Ser Arg Gln Gln Gln  Gln Gln Gln 
    1715                 1720                 1725             


Gln Gln  Gln Gln Gln Gln Gln  Gln Gln Gln Gln Gln  Gln Ala Gln 
    1730                 1735                 1740             


Thr Leu  Ala Gln Ala Gln Ala  Gln Val Gln Ala His  Leu Gln Gln 
    1745                 1750                 1755             


Glu Leu  Gln Gln Gln Ala Ala  Leu Ile Gln Ser Gln  Leu Phe Asn 
    1760                 1765                 1770             


Pro Thr  Leu Leu Pro His Phe  Pro Met Thr Thr Glu  Thr Leu Leu 
    1775                 1780                 1785             


Gln Leu  Gln Gln Gln Gln His  Leu Leu Phe Pro Phe  Tyr Ile Pro 
    1790                 1795                 1800             


Ser Ala  Glu Phe Gln Leu Asn  Pro Glu Val Ser Leu  Pro Val Thr 
    1805                 1810                 1815             


Ser Gly  Ala Leu Thr Leu Thr  Gly Thr Gly Pro Gly  Leu Leu Glu 
    1820                 1825                 1830             


Asp Leu  Lys Ala Gln Val Gln  Val Pro Gln Gln Ser  His Gln Gln 
    1835                 1840                 1845             


Ile Leu  Pro Gln Gln Gln Gln  Asn Gln Leu Ser Ile  Ala Gln Ser 
    1850                 1855                 1860             


His Ser  Ala Leu Leu Gln Pro  Ser Gln His Pro Glu  Lys Lys Asn 
    1865                 1870                 1875             


Lys Leu  Val Ile Lys Glu Lys  Glu Lys Glu Ser Gln  Arg Glu Arg 
    1880                 1885                 1890             


Asp Ser  Ala Glu Gly Gly Glu  Gly Asn Thr Gly Pro  Lys Glu Thr 
    1895                 1900                 1905             


Leu Pro  Asp Ala Leu Lys Ala  Lys Glu Lys Lys Glu  Leu Ala Pro 
    1910                 1915                 1920             


Gly Gly  Gly Ser Glu Pro Ser  Met Leu Pro Pro Arg  Ile Ala Ser 
    1925                 1930                 1935             


Asp Ala  Arg Gly Asn Ala Thr  Lys Ala Leu Leu Glu  Asn Phe Gly 
    1940                 1945                 1950             


Phe Glu  Leu Val Ile Gln Tyr  Asn Glu Asn Lys Gln  Lys Val Gln 
    1955                 1960                 1965             


Lys Lys  Asn Gly Lys Thr Asp  Gln Gly Glu Asn Leu  Glu Lys Leu 
    1970                 1975                 1980             


Glu Cys  Asp Ser Cys Gly Lys  Leu Phe Ser Asn Ile  Leu Ile Leu 
    1985                 1990                 1995             


Lys Ser  His Gln Glu His Val  His Gln Asn Tyr Phe  Pro Phe Lys 
    2000                 2005                 2010             


Gln Leu  Glu Arg Phe Ala Lys  Gln Tyr Arg Asp His  Tyr Asp Lys 
    2015                 2020                 2025             


Leu Tyr  Pro Leu Arg Pro Gln  Thr Pro Glu Pro Pro  Pro Pro Pro 
    2030                 2035                 2040             


Pro Pro  Pro Pro Pro Pro Pro  Leu Pro Ala Ala Pro  Pro Gln Pro 
    2045                 2050                 2055             


Ala Ser  Thr Pro Ala Ile Pro  Ala Ser Ala Pro Pro  Ile Thr Ser 
    2060                 2065                 2070             


Pro Thr  Ile Ala Pro Ala Gln  Pro Ser Val Pro Leu  Thr Gln Leu 
    2075                 2080                 2085             


Ser Met  Pro Met Glu Leu Pro  Ile Phe Ser Pro Leu  Met Met Gln 
    2090                 2095                 2100             


Thr Met  Pro Leu Gln Thr Leu  Pro Ala Gln Leu Pro  Pro Gln Leu 
    2105                 2110                 2115             


Gly Pro  Val Glu Pro Leu Pro  Ala Asp Leu Ala Gln  Leu Tyr Gln 
    2120                 2125                 2130             


His Gln  Leu Asn Pro Thr Leu  Leu Gln Gln Gln Asn  Lys Arg Pro 
    2135                 2140                 2145             


Arg Thr  Arg Ile Thr Asp Asp  Gln Leu Arg Val Leu  Arg Gln Tyr 
    2150                 2155                 2160             


Phe Asp  Ile Asn Asn Ser Pro  Ser Glu Glu Gln Ile  Lys Glu Met 
    2165                 2170                 2175             


Ala Asp  Lys Ser Gly Leu Pro  Gln Lys Val Ile Lys  His Trp Phe 
    2180                 2185                 2190             


Arg Asn  Thr Leu Phe Lys Glu  Arg Gln Arg Asn Lys  Asp Ser Pro 
    2195                 2200                 2205             


Tyr Asn  Phe Ser Asn Pro Pro  Ile Thr Ser Leu Glu  Glu Leu Lys 
    2210                 2215                 2220             


Ile Asp  Ser Arg Pro Pro Ser  Pro Glu Pro Pro Lys  Gln Glu Tyr 
    2225                 2230                 2235             


Trp Gly  Ser Lys Arg Ser Ser  Arg Thr Arg Phe Thr  Asp Tyr Gln 
    2240                 2245                 2250             


Leu Arg  Val Leu Gln Asp Phe  Phe Asp Ala Asn Ala  Tyr Pro Lys 
    2255                 2260                 2265             


Asp Asp  Glu Phe Glu Gln Leu  Ser Asn Leu Leu Asn  Leu Pro Thr 
    2270                 2275                 2280             


Arg Val  Ile Val Val Trp Phe  Gln Asn Ala Arg Gln  Lys Ala Arg 
    2285                 2290                 2295             


Lys Asn  Tyr Glu Asn Gln Gly  Glu Gly Lys Asp Gly  Glu Arg Arg 
    2300                 2305                 2310             


Glu Leu  Thr Asn Asp Arg Tyr  Ile Arg Thr Ser Asn  Leu Asn Tyr 
    2315                 2320                 2325             


Gln Cys  Lys Lys Cys Ser Leu  Val Phe Gln Arg Ile  Phe Asp Leu 
    2330                 2335                 2340             


Ile Lys  His Gln Lys Lys Leu  Cys Tyr Lys Asp Glu  Asp Glu Glu 
    2345                 2350                 2355             


Gly Gln  Asp Asp Ser Gln Asn  Glu Asp Ser Met Asp  Ala Met Glu 
    2360                 2365                 2370             


Ile Leu  Thr Pro Thr Ser Ser  Ser Cys Ser Thr Pro  Met Pro Ser 
    2375                 2380                 2385             


Gln Ala  Tyr Ser Ala Pro Ala  Pro Ser Ala Asn Asn  Thr Ala Ser 
    2390                 2395                 2400             


Ser Ala  Phe Leu Gln Leu Thr  Ala Glu Ala Glu Glu  Leu Ala Thr 
    2405                 2410                 2415             


Phe Asn  Ser Lys Thr Glu Ala  Gly Asp Glu Lys Pro  Lys Leu Ala 
    2420                 2425                 2430             


Glu Ala  Pro Ser Ala Gln Pro  Asn Gln Thr Gln Glu  Lys Gln Gly 
    2435                 2440                 2445             


Gln Pro  Lys Pro Glu Leu Gln  Gln Gln Glu Gln Pro  Glu Gln Lys 
    2450                 2455                 2460             


Thr Asn  Thr Pro Gln Gln Lys  Leu Pro Gln Leu Val  Ser Leu Pro 
    2465                 2470                 2475             


Ser Leu  Pro Gln Pro Pro Pro  Gln Ala Pro Pro Pro  Gln Cys Pro 
    2480                 2485                 2490             


Leu Pro  Gln Ser Ser Pro Ser  Pro Ser Gln Leu Ser  His Leu Pro 
    2495                 2500                 2505             


Leu Lys  Pro Leu His Thr Ser  Thr Pro Gln Gln Leu  Ala Asn Leu 
    2510                 2515                 2520             


Pro Pro  Gln Leu Ile Pro Tyr  Gln Cys Asp Gln Cys  Lys Leu Ala 
    2525                 2530                 2535             


Phe Pro  Ser Phe Glu His Trp  Gln Glu His Gln Gln  Leu His Phe 
    2540                 2545                 2550             


Leu Ser  Ala Gln Asn Gln Phe  Ile His Pro Gln Phe  Leu Asp Arg 
    2555                 2560                 2565             


Ser Leu  Asp Met Pro Phe Met  Leu Phe Asp Pro Ser  Asn Pro Leu 
    2570                 2575                 2580             


Leu Ala  Ser Gln Leu Leu Ser  Gly Ala Ile Pro Gln  Ile Pro Ala 
    2585                 2590                 2595             


Ser Ser  Ala Thr Ser Pro Ser  Thr Pro Thr Ser Thr  Met Asn Thr 
    2600                 2605                 2610             


Leu Lys  Arg Lys Leu Glu Glu  Lys Ala Ser Ala Ser  Pro Gly Glu 
    2615                 2620                 2625             


Asn Asp  Ser Gly Thr Gly Gly  Glu Glu Pro Gln Arg  Asp Lys Arg 
    2630                 2635                 2640             


Leu Arg  Thr Thr Ile Thr Pro  Glu Gln Leu Glu Ile  Leu Tyr Gln 
    2645                 2650                 2655             


Lys Tyr  Leu Leu Asp Ser Asn  Pro Thr Arg Lys Met  Leu Asp His 
    2660                 2665                 2670             


Ile Ala  His Glu Val Gly Leu  Lys Lys Arg Val Val  Gln Val Trp 
    2675                 2680                 2685             


Phe Gln  Asn Thr Arg Ala Arg  Glu Arg Lys Gly Gln  Phe Arg Ala 
    2690                 2695                 2700             


Val Gly  Pro Ala Gln Ala His  Arg Arg Cys Pro Phe  Cys Arg Ala 
    2705                 2710                 2715             


Leu Phe  Lys Ala Lys Thr Ala  Leu Glu Ala His Ile  Arg Ser Arg 
    2720                 2725                 2730             


His Trp  His Glu Ala Lys Arg  Ala Gly Tyr Asn Leu  Thr Leu Ser 
    2735                 2740                 2745             


Ala Met  Leu Leu Asp Cys Asp  Gly Gly Leu Gln Met  Lys Gly Asp 
    2750                 2755                 2760             


Ile Phe  Asp Gly Thr Ser Phe  Ser His Leu Pro Pro  Ser Ser Ser 
    2765                 2770                 2775             


Asp Gly  Gln Gly Val Pro Leu  Ser Pro Val Ser Lys  Thr Met Glu 
    2780                 2785                 2790             


Leu Ser  Pro Arg Thr Leu Leu  Ser Pro Ser Ser Ile  Lys Val Glu 
    2795                 2800                 2805             


Gly Ile  Glu Asp Phe Glu Ser  Pro Ser Met Ser Ser  Val Asn Leu 
    2810                 2815                 2820             


Asn Phe  Asp Gln Thr Lys Leu  Asp Asn Asp Asp Cys  Ser Ser Val 
    2825                 2830                 2835             


Asn Thr  Ala Ile Thr Asp Thr  Thr Thr Gly Asp Glu  Gly Asn Ala 
    2840                 2845                 2850             


Asp Asn  Asp Ser Ala Thr Gly  Ile Ala Thr Glu Thr  Lys Ser Ser 
    2855                 2860                 2865             


Ser Ala  Pro Asn Glu Gly Leu  Thr Lys Ala Ala Met  Met Ala Met 
    2870                 2875                 2880             


Ser Glu  Tyr Glu Asp Arg Leu  Ser Ser Gly Leu Val  Ser Pro Ala 
    2885                 2890                 2895             


Pro Ser  Phe Tyr Ser Lys Glu  Tyr Asp Asn Glu Gly  Thr Val Asp 
    2900                 2905                 2910             


Tyr Ser  Glu Thr Ser Ser Leu  Ala Asp Pro Cys Ser  Pro Ser Pro 
    2915                 2920                 2925             


Gly Ala  Ser Gly Ser Ala Gly  Lys Ser Gly Asp Ser  Gly Asp Arg 
    2930                 2935                 2940             


Pro Gly  Gln Lys Arg Phe Arg  Thr Gln Met Thr Asn  Leu Gln Leu 
    2945                 2950                 2955             


Lys Val  Leu Lys Ser Cys Phe  Asn Asp Tyr Arg Thr  Pro Thr Met 
    2960                 2965                 2970             


Leu Glu  Cys Glu Val Leu Gly  Asn Asp Ile Gly Leu  Pro Lys Arg 
    2975                 2980                 2985             


Val Val  Gln Val Trp Phe Gln  Asn Ala Arg Ala Lys  Glu Lys Lys 
    2990                 2995                 3000             


Ser Lys  Leu Ser Met Ala Lys  His Phe Gly Ile Asn  Gln Thr Ser 
    3005                 3010                 3015             


Tyr Glu  Gly Pro Lys Thr Glu  Cys Thr Leu Cys Gly  Ile Lys Tyr 
    3020                 3025                 3030             


Ser Ala  Arg Leu Ser Val Arg  Asp His Ile Phe Ser  Gln Gln His 
    3035                 3040                 3045             


Ile Ser  Lys Val Lys Asp Thr  Ile Gly Ser Gln Leu  Asp Lys Glu 
    3050                 3055                 3060             


Lys Glu  Tyr Phe Asp Pro Ala  Thr Val Arg Gln Leu  Met Ala Gln 
    3065                 3070                 3075             


Gln Glu  Leu Asp Arg Ile Lys  Lys Ala Asn Glu Val  Leu Gly Leu 
    3080                 3085                 3090             


Ala Ala  Gln Gln Gln Gly Met  Phe Asp Asn Thr Pro  Leu Gln Ala 
    3095                 3100                 3105             


Leu Asn  Leu Pro Thr Ala Tyr  Pro Ala Leu Gln Gly  Ile Pro Pro 
    3110                 3115                 3120             


Val Leu  Leu Pro Gly Leu Asn  Ser Pro Ser Leu Pro  Gly Phe Thr 
    3125                 3130                 3135             


Pro Ser  Asn Thr Ala Leu Thr  Ser Pro Lys Pro Asn  Leu Met Gly 
    3140                 3145                 3150             


Leu Pro  Ser Thr Thr Val Pro  Ser Pro Gly Leu Pro  Thr Ser Gly 
    3155                 3160                 3165             


Leu Pro  Asn Lys Pro Ser Ser  Ala Ser Leu Ser Ser  Pro Thr Pro 
    3170                 3175                 3180             


Ala Gln  Ala Thr Met Ala Met  Gly Pro Gln Gln Pro  Pro Gln Gln 
    3185                 3190                 3195             


Gln Gln  Gln Gln Gln Gln Pro  Gln Val Gln Gln Pro  Pro Pro Pro 
    3200                 3205                 3210             


Pro Ala  Ala Gln Pro Pro Pro  Thr Pro Gln Leu Pro  Leu Gln Gln 
    3215                 3220                 3225             


Gln Gln  Gln Arg Lys Asp Lys  Asp Ser Glu Lys Val  Lys Glu Lys 
    3230                 3235                 3240             


Glu Lys  Ala His Lys Gly Lys  Gly Glu Pro Leu Pro  Val Pro Lys 
    3245                 3250                 3255             


Lys Glu  Lys Gly Glu Ala Pro  Thr Ala Thr Ala Ala  Thr Ile Ser 
    3260                 3265                 3270             


Ala Pro  Leu Pro Thr Met Glu  Tyr Ala Val Asp Pro  Ala Gln Leu 
    3275                 3280                 3285             


Gln Ala  Leu Gln Ala Ala Leu  Thr Ser Asp Pro Thr  Ala Leu Leu 
    3290                 3295                 3300             


Thr Ser  Gln Phe Leu Pro Tyr  Phe Val Pro Gly Phe  Ser Pro Tyr 
    3305                 3310                 3315             


Tyr Ala  Pro Gln Ile Pro Gly  Ala Leu Gln Ser Gly  Tyr Leu Gln 
    3320                 3325                 3330             


Pro Met  Tyr Gly Met Glu Gly  Leu Phe Pro Tyr Ser  Pro Ala Leu 
    3335                 3340                 3345             


Ser Gln  Ala Leu Met Gly Leu  Ser Pro Gly Ser Leu  Leu Gln Gln 
    3350                 3355                 3360             


Tyr Gln  Gln Tyr Gln Gln Ser  Leu Gln Glu Ala Ile  Gln Gln Gln 
    3365                 3370                 3375             


Gln Gln  Arg Gln Leu Gln Gln  Gln Gln Gln Gln Lys  Val Gln Gln 
    3380                 3385                 3390             


Gln Gln  Pro Lys Ala Ser Gln  Thr Pro Val Pro Pro  Gly Ala Pro 
    3395                 3400                 3405             


Ser Pro  Asp Lys Asp Pro Ala  Lys Glu Ser Pro Lys  Pro Glu Glu 
    3410                 3415                 3420             


Gln Lys  Asn Thr Pro Arg Glu  Val Ser Pro Leu Leu  Pro Lys Leu 
    3425                 3430                 3435             


Pro Glu  Glu Pro Glu Ala Glu  Ser Lys Ser Ala Asp  Ser Leu Tyr 
    3440                 3445                 3450             


Asp Pro  Phe Ile Val Pro Lys  Val Gln Tyr Lys Leu  Val Cys Arg 
    3455                 3460                 3465             


Lys Cys  Gln Ala Gly Phe Ser  Asp Glu Glu Ala Ala  Arg Ser His 
    3470                 3475                 3480             


Leu Lys  Ser Leu Cys Phe Phe  Gly Gln Ser Val Val  Asn Leu Gln 
    3485                 3490                 3495             


Glu Met  Val Leu His Val Pro  Thr Gly Gly Gly Gly  Gly Gly Ser 
    3500                 3505                 3510             


Gly Gly  Gly Gly Gly Gly Gly  Gly Gly Gly Gly Gly  Gly Gly Ser 
    3515                 3520                 3525             


Tyr His  Cys Leu Ala Cys Glu  Ser Ala Leu Cys Gly  Glu Glu Ala 
    3530                 3535                 3540             


Leu Ser  Gln His Leu Glu Ser  Ala Leu His Lys His  Arg Thr Ile 
    3545                 3550                 3555             


Thr Arg  Ala Ala Arg Asn Ala  Lys Glu His Pro Ser  Leu Leu Pro 
    3560                 3565                 3570             


His Ser  Ala Cys Phe Pro Asp  Pro Ser Thr Ala Ser  Thr Ser Gln 
    3575                 3580                 3585             


Ser Ala  Ala His Ser Asn Asp  Ser Pro Pro Pro Pro  Ser Ala Ala 
    3590                 3595                 3600             


Ala Pro  Ser Ser Ala Ser Pro  His Ala Ser Arg Lys  Ser Trp Pro 
    3605                 3610                 3615             


Gln Val  Val Ser Arg Ala Ser  Ala Ala Lys Pro Pro  Ser Phe Pro 
    3620                 3625                 3630             


Pro Leu  Ser Ser Ser Ser Thr  Val Thr Ser Ser Ser  Cys Ser Thr 
    3635                 3640                 3645             


Ser Gly  Val Gln Pro Ser Met  Pro Thr Asp Asp Tyr  Ser Glu Glu 
    3650                 3655                 3660             


Ser Asp  Thr Asp Leu Ser Gln  Lys Ser Asp Gly Pro  Ala Ser Pro 
    3665                 3670                 3675             


Val Glu  Gly Pro Lys Asp Pro  Ser Cys Pro Lys Asp  Ser Gly Leu 
    3680                 3685                 3690             


Thr Ser  Val Gly Thr Asp Thr  Phe Arg Leu 
    3695                 3700             


<210>  4152
<211>  653
<212>  PRT
<213>  homo sapiens

<400>  4152

Met His Trp Thr Pro Glu His Ala Gln Pro Leu Asn Gln Trp Pro Glu 
1               5                   10                  15      


Gln His Leu Asp Val Ser Ser Thr Thr Pro Ser Pro Ala His Lys Leu 
            20                  25                  30          


Glu Leu Pro Pro Gly Gly Arg Gln Arg Cys His Tyr Ala Trp Ala His 
        35                  40                  45              


Asp Asp Ile Ser Ala Leu Thr Ala Ser Asn Leu Leu Lys Arg Tyr Ala 
    50                  55                  60                  


Glu Lys Tyr Ser Gly Val Leu Asp Ser Pro Tyr Glu Arg Pro Ala Leu 
65                  70                  75                  80  


Gly Gly Tyr Ser Asp Ala Ser Phe Leu Asn Gly Ala Lys Gly Asp Pro 
                85                  90                  95      


Glu Pro Trp Pro Gly Pro Glu Pro Pro Tyr Pro Leu Ala Ser Leu His 
            100                 105                 110         


Glu Gly Leu Pro Gly Thr Lys Ser Gly Gly Gly Gly Gly Ser Gly Ala 
        115                 120                 125             


Leu Gly Gly Ser Pro Val Leu Ala Gly Asn Leu Pro Glu Pro Leu Tyr 
    130                 135                 140                 


Ala Gly Asn Ala Cys Gly Gly Pro Ser Ala Ala Pro Glu Tyr Ala Ala 
145                 150                 155                 160 


Gly Tyr Gly Gly Gly Tyr Leu Ala Pro Gly Tyr Cys Ala Gln Thr Gly 
                165                 170                 175     


Ala Ala Leu Pro Pro Pro Pro Pro Ala Ala Leu Leu Gln Pro Pro Pro 
            180                 185                 190         


Pro Pro Gly Tyr Gly Pro Ser Ala Pro Leu Tyr Asn Tyr Pro Ala Gly 
        195                 200                 205             


Gly Tyr Ala Ala Gln Pro Gly Tyr Gly Ala Leu Pro Pro Pro Pro Gly 
    210                 215                 220                 


Pro Pro Pro Ala Pro Tyr Leu Thr Pro Gly Leu Pro Ala Pro Thr Pro 
225                 230                 235                 240 


Leu Pro Ala Pro Ala Pro Pro Thr Ala Tyr Gly Phe Pro Thr Ala Ala 
                245                 250                 255     


Pro Gly Ala Glu Ser Gly Leu Ser Leu Lys Arg Lys Ala Ala Asp Glu 
            260                 265                 270         


Gly Pro Glu Gly Arg Tyr Arg Lys Tyr Ala Tyr Glu Pro Ala Lys Ala 
        275                 280                 285             


Pro Val Ala Asp Gly Ala Ser Tyr Pro Ala Ala Asp Asn Gly Glu Cys 
    290                 295                 300                 


Arg Gly Asn Gly Phe Arg Ala Lys Pro Pro Gly Ala Ala Glu Glu Ala 
305                 310                 315                 320 


Ser Gly Lys Tyr Gly Gly Gly Val Pro Leu Lys Val Leu Gly Ser Pro 
                325                 330                 335     


Val Tyr Gly Pro Gln Leu Glu Pro Phe Glu Lys Phe Pro Glu Arg Ala 
            340                 345                 350         


Pro Ala Pro Arg Gly Gly Phe Ala Val Pro Ser Gly Glu Thr Pro Lys 
        355                 360                 365             


Gly Val Asp Pro Gly Ala Leu Glu Leu Val Thr Ser Lys Met Val Asp 
    370                 375                 380                 


Cys Gly Pro Pro Val Gln Trp Ala Asp Val Ala Gly Gln Gly Ala Leu 
385                 390                 395                 400 


Lys Ala Ala Leu Glu Glu Glu Leu Val Trp Pro Leu Leu Arg Pro Pro 
                405                 410                 415     


Ala Tyr Pro Gly Ser Leu Arg Pro Pro Arg Thr Val Leu Leu Phe Gly 
            420                 425                 430         


Pro Arg Gly Ala Gly Lys Ala Leu Leu Gly Arg Cys Leu Ala Thr Gln 
        435                 440                 445             


Leu Gly Ala Thr Leu Leu Arg Leu Arg Gly Ala Thr Leu Ala Ala Pro 
    450                 455                 460                 


Gly Ala Ala Glu Gly Ala Arg Leu Leu Gln Ala Ala Phe Ala Ala Ala 
465                 470                 475                 480 


Arg Cys Arg Pro Pro Ser Val Leu Leu Ile Ser Glu Leu Glu Ala Leu 
                485                 490                 495     


Leu Pro Ala Arg Asp Asp Gly Ala Ala Ala Gly Gly Ala Leu Gln Val 
            500                 505                 510         


Pro Leu Leu Ala Cys Leu Asp Gly Gly Cys Gly Ala Gly Ala Asp Gly 
        515                 520                 525             


Val Leu Val Val Gly Thr Thr Ser Arg Pro Ala Ala Leu Asp Glu Ala 
    530                 535                 540                 


Thr Arg Arg Arg Phe Ser Leu Arg Phe Tyr Val Ala Leu Pro Asp Ser 
545                 550                 555                 560 


Pro Ala Arg Gly Gln Ile Leu Gln Arg Ala Leu Ala Gln Gln Gly Cys 
                565                 570                 575     


Ala Leu Ser Glu Arg Glu Leu Ala Ala Leu Val Gln Gly Thr Gln Gly 
            580                 585                 590         


Phe Ser Gly Gly Glu Leu Gly Gln Leu Cys Gln Gln Ala Ala Ala Gly 
        595                 600                 605             


Ala Gly Leu Pro Gly Leu Gln Arg Pro Leu Ser Tyr Lys Asp Leu Glu 
    610                 615                 620                 


Ala Ala Leu Ala Lys Val Gly Pro Arg Ala Ser Ala Lys Glu Leu Asp 
625                 630                 635                 640 


Ser Phe Val Glu Trp Asp Lys Met Tyr Gly Ser Gly His 
                645                 650             


<210>  4153
<211>  227
<212>  PRT
<213>  homo sapiens

<400>  4153

Met Gly Gly Lys Leu Ser Lys Lys Lys Lys Gly Tyr Asn Val Asn Asp 
1               5                   10                  15      


Glu Lys Ala Lys Glu Lys Asp Lys Lys Ala Glu Gly Ala Ala Thr Glu 
            20                  25                  30          


Glu Glu Gly Thr Pro Lys Glu Ser Glu Pro Gln Ala Ala Ala Glu Pro 
        35                  40                  45              


Ala Glu Ala Lys Glu Gly Lys Glu Lys Pro Asp Gln Asp Ala Glu Gly 
    50                  55                  60                  


Lys Ala Glu Glu Lys Glu Gly Glu Lys Asp Ala Ala Ala Ala Lys Glu 
65                  70                  75                  80  


Glu Ala Pro Lys Ala Glu Pro Glu Lys Thr Glu Gly Ala Ala Glu Ala 
                85                  90                  95      


Lys Ala Glu Pro Pro Lys Ala Pro Glu Gln Glu Gln Ala Ala Pro Gly 
            100                 105                 110         


Pro Ala Ala Gly Gly Glu Ala Pro Lys Ala Ala Glu Ala Ala Ala Ala 
        115                 120                 125             


Pro Ala Glu Ser Ala Ala Pro Ala Ala Gly Glu Glu Pro Ser Lys Glu 
    130                 135                 140                 


Glu Gly Glu Pro Lys Lys Thr Glu Ala Pro Ala Ala Pro Ala Ala Gln 
145                 150                 155                 160 


Glu Thr Lys Ser Asp Gly Ala Pro Ala Ser Asp Ser Lys Pro Gly Ser 
                165                 170                 175     


Ser Glu Ala Ala Pro Ser Ser Lys Glu Thr Pro Ala Ala Thr Glu Ala 
            180                 185                 190         


Pro Ser Ser Thr Pro Lys Ala Gln Gly Pro Ala Ala Ser Ala Glu Glu 
        195                 200                 205             


Pro Lys Pro Val Glu Ala Pro Ala Ala Asn Ser Asp Gln Thr Val Thr 
    210                 215                 220                 


Val Lys Glu 
225         


<210>  4154
<211>  112
<212>  PRT
<213>  homo sapiens

<400>  4154

Met Gln Asp Thr Gly Ser Val Val Pro Leu His Trp Phe Gly Phe Gly 
1               5                   10                  15      


Tyr Ala Ala Leu Val Ala Ser Gly Gly Ile Ile Gly Tyr Val Lys Ala 
            20                  25                  30          


Gly Ser Val Pro Ser Leu Ala Ala Gly Leu Leu Phe Gly Ser Leu Ala 
        35                  40                  45              


Gly Leu Gly Ala Tyr Gln Leu Ser Gln Asp Pro Arg Asn Val Trp Val 
    50                  55                  60                  


Phe Leu Ala Thr Ser Gly Thr Leu Ala Gly Ile Met Gly Met Arg Phe 
65                  70                  75                  80  


Tyr His Ser Gly Lys Phe Met Pro Ala Gly Leu Ile Ala Gly Ala Ser 
                85                  90                  95      


Leu Leu Met Val Ala Lys Val Gly Val Ser Met Phe Asn Arg Pro His 
            100                 105                 110         


<210>  4155
<211>  1214
<212>  PRT
<213>  homo sapiens

<400>  4155

Met Ala Val Arg Lys Lys Asp Gly Gly Pro Asn Val Lys Tyr Tyr Glu 
1               5                   10                  15      


Ala Ala Asp Thr Val Thr Gln Phe Asp Asn Val Arg Leu Trp Leu Gly 
            20                  25                  30          


Lys Asn Tyr Lys Lys Tyr Ile Gln Ala Glu Pro Pro Thr Asn Lys Ser 
        35                  40                  45              


Leu Ser Ser Leu Val Val Gln Leu Leu Gln Phe Gln Glu Glu Val Phe 
    50                  55                  60                  


Gly Lys His Val Ser Asn Ala Pro Leu Thr Lys Leu Pro Ile Lys Cys 
65                  70                  75                  80  


Phe Leu Asp Phe Lys Ala Gly Gly Ser Leu Cys His Ile Leu Ala Ala 
                85                  90                  95      


Ala Tyr Lys Phe Lys Ser Asp Gln Gly Trp Arg Arg Tyr Asp Phe Gln 
            100                 105                 110         


Asn Pro Ser Arg Met Asp Arg Asn Val Glu Met Phe Met Thr Ile Glu 
        115                 120                 125             


Lys Ser Leu Val Gln Asn Asn Cys Leu Ser Arg Pro Asn Ile Phe Leu 
    130                 135                 140                 


Cys Pro Glu Ile Glu Pro Lys Leu Leu Gly Lys Leu Lys Asp Ile Ile 
145                 150                 155                 160 


Lys Arg His Gln Gly Thr Val Thr Glu Asp Lys Asn Asn Ala Ser His 
                165                 170                 175     


Val Val Tyr Pro Val Pro Gly Asn Leu Glu Glu Glu Glu Trp Val Arg 
            180                 185                 190         


Pro Val Met Lys Arg Asp Lys Gln Val Leu Leu His Trp Gly Tyr Tyr 
        195                 200                 205             


Pro Asp Ser Tyr Asp Thr Trp Ile Pro Ala Ser Glu Ile Glu Ala Ser 
    210                 215                 220                 


Val Glu Asp Ala Pro Thr Pro Glu Lys Pro Arg Lys Val His Ala Lys 
225                 230                 235                 240 


Trp Ile Leu Asp Thr Asp Thr Phe Asn Glu Trp Met Asn Glu Glu Asp 
                245                 250                 255     


Tyr Glu Val Asn Asp Asp Lys Asn Pro Val Ser Arg Arg Lys Lys Ile 
            260                 265                 270         


Ser Ala Lys Thr Leu Thr Asp Glu Val Asn Ser Pro Asp Ser Asp Arg 
        275                 280                 285             


Arg Asp Lys Lys Gly Gly Asn Tyr Lys Lys Arg Lys Arg Ser Pro Ser 
    290                 295                 300                 


Pro Ser Pro Thr Pro Glu Ala Lys Lys Lys Asn Ala Lys Lys Gly Pro 
305                 310                 315                 320 


Ser Thr Pro Tyr Thr Lys Ser Lys Arg Gly His Arg Glu Glu Glu Gln 
                325                 330                 335     


Glu Asp Leu Thr Lys Asp Met Asp Glu Pro Ser Pro Val Pro Asn Val 
            340                 345                 350         


Glu Glu Val Thr Leu Pro Lys Thr Val Asn Thr Lys Lys Asp Ser Glu 
        355                 360                 365             


Ser Ala Pro Val Lys Gly Gly Thr Met Thr Asp Leu Asp Glu Gln Glu 
    370                 375                 380                 


Asp Glu Ser Met Glu Thr Thr Gly Lys Asp Glu Asp Glu Asn Ser Thr 
385                 390                 395                 400 


Gly Asn Lys Gly Glu Gln Thr Lys Asn Pro Asp Leu His Glu Asp Asn 
                405                 410                 415     


Val Thr Glu Gln Thr His His Ile Ile Ile Pro Ser Tyr Ala Ala Trp 
            420                 425                 430         


Phe Asp Tyr Asn Ser Val His Ala Ile Glu Arg Arg Ala Leu Pro Glu 
        435                 440                 445             


Phe Phe Asn Gly Lys Asn Lys Ser Lys Thr Pro Glu Ile Tyr Leu Ala 
    450                 455                 460                 


Tyr Arg Asn Phe Met Ile Asp Thr Tyr Arg Leu Asn Pro Gln Glu Tyr 
465                 470                 475                 480 


Leu Thr Ser Thr Ala Cys Arg Arg Asn Leu Ala Gly Asp Val Cys Ala 
                485                 490                 495     


Ile Met Arg Val His Ala Phe Leu Glu Gln Trp Gly Leu Ile Asn Tyr 
            500                 505                 510         


Gln Val Asp Ala Glu Ser Arg Pro Thr Pro Met Gly Pro Pro Pro Thr 
        515                 520                 525             


Ser His Phe His Val Leu Ala Asp Thr Pro Ser Gly Leu Val Pro Leu 
    530                 535                 540                 


Gln Pro Lys Thr Pro Gln Gln Thr Ser Ala Ser Gln Gln Met Leu Asn 
545                 550                 555                 560 


Phe Pro Asp Lys Gly Lys Glu Lys Pro Thr Asp Met Gln Asn Phe Gly 
                565                 570                 575     


Leu Arg Thr Asp Met Tyr Thr Lys Lys Asn Val Pro Ser Lys Ser Lys 
            580                 585                 590         


Ala Ala Ala Ser Ala Thr Arg Glu Trp Thr Glu Gln Glu Thr Leu Leu 
        595                 600                 605             


Leu Leu Glu Ala Leu Glu Met Tyr Lys Asp Asp Trp Asn Lys Val Ser 
    610                 615                 620                 


Glu His Val Gly Ser Arg Thr Gln Asp Glu Cys Ile Leu His Phe Leu 
625                 630                 635                 640 


Arg Leu Pro Ile Glu Asp Pro Tyr Leu Glu Asp Ser Glu Ala Ser Leu 
                645                 650                 655     


Gly Pro Leu Ala Tyr Gln Pro Ile Pro Phe Ser Gln Ser Gly Asn Pro 
            660                 665                 670         


Val Met Ser Thr Val Ala Phe Leu Ala Ser Val Val Asp Pro Arg Val 
        675                 680                 685             


Ala Ser Ala Ala Ala Lys Ser Ala Leu Glu Glu Phe Ser Lys Met Lys 
    690                 695                 700                 


Glu Glu Val Pro Thr Ala Leu Val Glu Ala His Val Arg Lys Val Glu 
705                 710                 715                 720 


Glu Ala Ala Lys Val Thr Gly Lys Ala Asp Pro Ala Phe Gly Leu Glu 
                725                 730                 735     


Ser Ser Gly Ile Ala Gly Thr Thr Ser Asp Glu Pro Glu Arg Ile Glu 
            740                 745                 750         


Glu Ser Gly Asn Asp Glu Ala Arg Val Glu Gly Gln Ala Thr Asp Glu 
        755                 760                 765             


Lys Lys Glu Pro Lys Glu Pro Arg Glu Gly Gly Gly Ala Ile Glu Glu 
    770                 775                 780                 


Glu Ala Lys Glu Lys Thr Ser Glu Ala Pro Lys Lys Asp Glu Glu Lys 
785                 790                 795                 800 


Gly Lys Glu Gly Asp Ser Glu Lys Glu Ser Glu Lys Ser Asp Gly Asp 
                805                 810                 815     


Pro Ile Val Asp Pro Glu Lys Glu Lys Glu Pro Lys Glu Gly Gln Glu 
            820                 825                 830         


Glu Val Leu Lys Glu Val Val Glu Ser Glu Gly Glu Arg Lys Thr Lys 
        835                 840                 845             


Val Glu Arg Asp Ile Gly Glu Gly Asn Leu Ser Thr Ala Ala Ala Ala 
    850                 855                 860                 


Ala Leu Ala Ala Ala Ala Val Lys Ala Lys His Leu Ala Ala Val Glu 
865                 870                 875                 880 


Glu Arg Lys Ile Lys Ser Leu Val Ala Leu Leu Val Glu Thr Gln Met 
                885                 890                 895     


Lys Lys Leu Glu Ile Lys Leu Arg His Phe Glu Glu Leu Glu Thr Ile 
            900                 905                 910         


Met Asp Arg Glu Arg Glu Ala Leu Glu Tyr Gln Arg Gln Gln Leu Leu 
        915                 920                 925             


Ala Asp Arg Gln Ala Phe His Met Glu Gln Leu Lys Tyr Ala Glu Met 
    930                 935                 940                 


Arg Ala Arg Gln Gln His Phe Gln Gln Met His Gln Gln Gln Gln Gln 
945                 950                 955                 960 


Pro Pro Pro Ala Leu Pro Pro Gly Ser Gln Pro Ile Pro Pro Thr Gly 
                965                 970                 975     


Ala Ala Gly Pro Pro Ala Val His Gly Leu Ala Val Ala Pro Ala Ser 
            980                 985                 990         


Val Val Pro Ala Pro Ala Gly Ser  Gly Ala Pro Pro Gly  Ser Leu Gly 
        995                 1000                 1005             


Pro Ser  Glu Gln Ile Gly Gln  Ala Gly Ser Thr Ala  Gly Pro Gln 
    1010                 1015                 1020             


Gln Gln  Gln Pro Ala Gly Ala  Pro Gln Pro Gly Ala  Val Pro Pro 
    1025                 1030                 1035             


Gly Val  Pro Pro Pro Gly Pro  His Gly Pro Ser Pro  Phe Pro Asn 
    1040                 1045                 1050             


Gln Gln  Thr Pro Pro Ser Met  Met Pro Gly Ala Val  Pro Gly Ser 
    1055                 1060                 1065             


Gly His  Pro Gly Val Ala Gly  Asn Ala Pro Leu Gly  Leu Pro Phe 
    1070                 1075                 1080             


Gly Met  Pro Pro Pro Pro Pro  Pro Pro Ala Pro Ser  Ile Ile Pro 
    1085                 1090                 1095             


Phe Gly  Ser Leu Ala Asp Ser  Ile Ser Ile Asn Leu  Pro Ala Pro 
    1100                 1105                 1110             


Pro Asn  Leu His Gly His His  His His Leu Pro Phe  Ala Pro Gly 
    1115                 1120                 1125             


Thr Leu  Pro Pro Pro Asn Leu  Pro Val Ser Met Ala  Asn Pro Leu 
    1130                 1135                 1140             


His Pro  Asn Leu Pro Ala Thr  Thr Thr Met Pro Ser  Ser Leu Pro 
    1145                 1150                 1155             


Leu Gly  Pro Gly Leu Gly Ser  Ala Ala Ala Gln Ser  Pro Ala Ile 
    1160                 1165                 1170             


Val Ala  Ala Val Gln Gly Asn  Leu Leu Pro Ser Ala  Ser Pro Leu 
    1175                 1180                 1185             


Pro Asp  Pro Gly Thr Pro Leu  Pro Pro Asp Pro Thr  Ala Pro Ser 
    1190                 1195                 1200             


Pro Gly  Thr Val Thr Pro Val  Pro Pro Pro Gln 
    1205                 1210                 


<210>  4156
<211>  1130
<212>  PRT
<213>  homo sapiens

<400>  4156

Met Ala Val Arg Lys Lys Asp Gly Gly Pro Asn Val Lys Tyr Tyr Glu 
1               5                   10                  15      


Ala Ala Asp Thr Val Thr Gln Phe Asp Asn Val Arg Leu Trp Leu Gly 
            20                  25                  30          


Lys Asn Tyr Lys Lys Tyr Ile Gln Ala Glu Pro Pro Thr Asn Lys Ser 
        35                  40                  45              


Leu Ser Ser Leu Val Val Gln Leu Leu Gln Phe Gln Glu Glu Val Phe 
    50                  55                  60                  


Gly Lys His Val Ser Asn Ala Pro Leu Thr Lys Leu Pro Ile Lys Cys 
65                  70                  75                  80  


Phe Leu Asp Phe Lys Ala Gly Gly Ser Leu Cys His Ile Leu Ala Ala 
                85                  90                  95      


Ala Tyr Lys Phe Lys Ser Asp Gln Gly Trp Arg Arg Tyr Asp Phe Gln 
            100                 105                 110         


Asn Pro Ser Arg Met Asp Arg Asn Val Glu Met Phe Met Thr Ile Glu 
        115                 120                 125             


Lys Ser Leu Val Gln Asn Asn Cys Leu Ser Arg Pro Asn Ile Phe Leu 
    130                 135                 140                 


Cys Pro Glu Ile Glu Pro Lys Leu Leu Gly Lys Leu Lys Asp Ile Ile 
145                 150                 155                 160 


Lys Arg His Gln Gly Thr Val Thr Glu Asp Lys Asn Asn Ala Ser His 
                165                 170                 175     


Val Val Tyr Pro Val Pro Gly Asn Leu Glu Glu Glu Glu Trp Val Arg 
            180                 185                 190         


Pro Val Met Lys Arg Asp Lys Gln Val Leu Leu His Trp Gly Tyr Tyr 
        195                 200                 205             


Pro Asp Ser Tyr Asp Thr Trp Ile Pro Ala Ser Glu Ile Glu Ala Ser 
    210                 215                 220                 


Val Glu Asp Ala Pro Thr Pro Glu Lys Pro Arg Lys Val His Ala Lys 
225                 230                 235                 240 


Trp Ile Leu Asp Thr Asp Thr Phe Asn Glu Trp Met Asn Glu Glu Asp 
                245                 250                 255     


Tyr Glu Val Asn Asp Asp Lys Asn Pro Val Ser Arg Arg Lys Lys Ile 
            260                 265                 270         


Ser Ala Lys Thr Leu Thr Asp Glu Val Asn Ser Pro Asp Ser Asp Arg 
        275                 280                 285             


Arg Asp Lys Lys Gly Gly Asn Tyr Lys Lys Arg Lys Arg Ser Pro Ser 
    290                 295                 300                 


Pro Ser Pro Thr Pro Glu Ala Lys Lys Lys Asn Ala Lys Lys Gly Pro 
305                 310                 315                 320 


Ser Thr Pro Tyr Thr Lys Ser Lys Arg Gly His Arg Glu Glu Glu Gln 
                325                 330                 335     


Glu Asp Leu Thr Lys Asp Met Asp Glu Pro Ser Pro Val Pro Asn Val 
            340                 345                 350         


Glu Glu Val Thr Leu Pro Lys Thr Val Asn Thr Lys Lys Asp Ser Glu 
        355                 360                 365             


Ser Ala Pro Val Lys Gly Gly Thr Met Thr Asp Leu Asp Glu Gln Glu 
    370                 375                 380                 


Asp Glu Ser Met Glu Thr Thr Gly Lys Asp Glu Asp Glu Asn Ser Thr 
385                 390                 395                 400 


Gly Asn Lys Gly Glu Gln Thr Lys Asn Pro Asp Leu His Glu Asp Asn 
                405                 410                 415     


Val Thr Glu Gln Thr His His Ile Ile Ile Pro Ser Tyr Ala Ala Trp 
            420                 425                 430         


Phe Asp Tyr Asn Ser Val His Ala Ile Glu Arg Arg Ala Leu Pro Glu 
        435                 440                 445             


Phe Phe Asn Gly Lys Asn Lys Ser Lys Thr Pro Glu Ile Tyr Leu Ala 
    450                 455                 460                 


Tyr Arg Asn Phe Met Ile Asp Thr Tyr Arg Leu Asn Pro Gln Glu Tyr 
465                 470                 475                 480 


Leu Thr Ser Thr Ala Cys Arg Arg Asn Leu Ala Gly Asp Val Cys Ala 
                485                 490                 495     


Ile Met Arg Val His Ala Phe Leu Glu Gln Trp Gly Leu Ile Asn Tyr 
            500                 505                 510         


Gln Val Asp Ala Glu Ser Arg Pro Thr Pro Met Gly Pro Pro Pro Thr 
        515                 520                 525             


Ser His Phe His Val Leu Ala Asp Thr Pro Ser Gly Leu Val Pro Leu 
    530                 535                 540                 


Gln Pro Lys Thr Pro Gln Gly Arg Gln Val Asp Ala Asp Thr Lys Ala 
545                 550                 555                 560 


Gly Arg Lys Gly Lys Glu Leu Asp Asp Leu Val Pro Glu Thr Ala Lys 
                565                 570                 575     


Gly Lys Pro Glu Leu Gln Thr Ser Ala Ser Gln Gln Met Leu Asn Phe 
            580                 585                 590         


Pro Asp Lys Gly Lys Glu Lys Pro Thr Asp Met Gln Asn Phe Gly Leu 
        595                 600                 605             


Arg Thr Asp Met Tyr Thr Lys Lys Asn Val Pro Ser Lys Ser Lys Ala 
    610                 615                 620                 


Ala Ala Ser Ala Thr Arg Glu Trp Thr Glu Gln Glu Thr Leu Leu Leu 
625                 630                 635                 640 


Leu Glu Ala Leu Glu Met Tyr Lys Asp Asp Trp Asn Lys Val Ser Glu 
                645                 650                 655     


His Val Gly Ser Arg Thr Gln Asp Glu Cys Ile Leu His Phe Leu Arg 
            660                 665                 670         


Leu Pro Ile Glu Asp Pro Tyr Leu Glu Asp Ser Glu Ala Ser Leu Gly 
        675                 680                 685             


Pro Leu Ala Tyr Gln Pro Ile Pro Phe Ser Gln Ser Gly Asn Pro Val 
    690                 695                 700                 


Met Ser Thr Val Ala Phe Leu Ala Ser Val Val Asp Pro Arg Val Ala 
705                 710                 715                 720 


Ser Ala Ala Ala Lys Ser Ala Leu Glu Glu Phe Ser Lys Met Lys Glu 
                725                 730                 735     


Glu Val Pro Thr Ala Leu Val Glu Ala His Val Arg Lys Val Glu Glu 
            740                 745                 750         


Ala Ala Lys Val Thr Gly Lys Ala Asp Pro Ala Phe Gly Leu Glu Ser 
        755                 760                 765             


Ser Gly Ile Ala Gly Thr Thr Ser Asp Glu Pro Glu Arg Ile Glu Glu 
    770                 775                 780                 


Ser Gly Asn Asp Glu Ala Arg Val Glu Gly Gln Ala Thr Asp Glu Lys 
785                 790                 795                 800 


Lys Glu Pro Lys Glu Pro Arg Glu Gly Gly Gly Ala Ile Glu Glu Glu 
                805                 810                 815     


Ala Lys Glu Lys Thr Ser Glu Ala Pro Lys Lys Asp Glu Glu Lys Gly 
            820                 825                 830         


Lys Glu Gly Asp Ser Glu Lys Glu Ser Glu Lys Ser Asp Gly Asp Pro 
        835                 840                 845             


Ile Val Asp Pro Glu Lys Glu Lys Glu Pro Lys Glu Gly Gln Glu Glu 
    850                 855                 860                 


Val Leu Lys Glu Val Val Glu Ser Glu Gly Glu Arg Lys Thr Lys Val 
865                 870                 875                 880 


Glu Arg Asp Ile Gly Glu Gly Asn Leu Ser Thr Ala Ala Ala Ala Ala 
                885                 890                 895     


Leu Ala Ala Ala Ala Val Lys Ala Lys His Leu Ala Ala Val Glu Glu 
            900                 905                 910         


Arg Lys Ile Lys Ser Leu Val Ala Leu Leu Val Glu Thr Gln Met Lys 
        915                 920                 925             


Lys Leu Glu Ile Lys Leu Arg His Phe Glu Glu Leu Glu Thr Ile Met 
    930                 935                 940                 


Asp Arg Glu Arg Glu Ala Leu Glu Tyr Gln Arg Gln Gln Leu Leu Ala 
945                 950                 955                 960 


Asp Arg Gln Ala Phe His Met Glu Gln Leu Lys Tyr Ala Glu Met Arg 
                965                 970                 975     


Ala Arg Gln Gln His Phe Gln Gln Met His Gln Gln Gln Gln Gln Pro 
            980                 985                 990         


Pro Pro Ala Leu Pro Pro Gly Ser  Gln Pro Ile Pro Pro  Thr Gly Ala 
        995                 1000                 1005             


Ala Gly  Pro Pro Ala Val His  Gly Leu Ala Val Ala  Pro Ala Ser 
    1010                 1015                 1020             


Val Val  Pro Ala Pro Ala Gly  Ser Gly Ala Pro Pro  Gly Ser Leu 
    1025                 1030                 1035             


Gly Pro  Ser Glu Gln Ile Gly  Gln Ala Gly Ser Thr  Ala Gly Pro 
    1040                 1045                 1050             


Gln Gln  Gln Gln Pro Ala Gly  Ala Pro Gln Pro Gly  Ala Val Pro 
    1055                 1060                 1065             


Pro Gly  Val Pro Pro Pro Gly  Pro His Gly Pro Ser  Pro Phe Pro 
    1070                 1075                 1080             


Asn Gln  Gln Thr Pro Pro Ser  Met Met Pro Gly Ala  Val Pro Gly 
    1085                 1090                 1095             


Ser Gly  His Pro Gly Val Ala  Asp Pro Gly Thr Pro  Leu Pro Pro 
    1100                 1105                 1110             


Asp Pro  Thr Ala Pro Ser Pro  Gly Thr Val Thr Pro  Val Pro Pro 
    1115                 1120                 1125             


Pro Gln  
    1130 


<210>  4157
<211>  672
<212>  PRT
<213>  homo sapiens

<400>  4157

Met Ala Asp Val Phe Pro Gly Asn Asp Ser Thr Ala Ser Gln Asp Val 
1               5                   10                  15      


Ala Asn Arg Phe Ala Arg Lys Gly Ala Leu Arg Gln Lys Asn Val His 
            20                  25                  30          


Glu Val Lys Asp His Lys Phe Ile Ala Arg Phe Phe Lys Gln Pro Thr 
        35                  40                  45              


Phe Cys Ser His Cys Thr Asp Phe Ile Trp Gly Phe Gly Lys Gln Gly 
    50                  55                  60                  


Phe Gln Cys Gln Val Cys Cys Phe Val Val His Lys Arg Cys His Glu 
65                  70                  75                  80  


Phe Val Thr Phe Ser Cys Pro Gly Ala Asp Lys Gly Pro Asp Thr Asp 
                85                  90                  95      


Asp Pro Arg Ser Lys His Lys Phe Lys Ile His Thr Tyr Gly Ser Pro 
            100                 105                 110         


Thr Phe Cys Asp His Cys Gly Ser Leu Leu Tyr Gly Leu Ile His Gln 
        115                 120                 125             


Gly Met Lys Cys Asp Thr Cys Asp Met Asn Val His Lys Gln Cys Val 
    130                 135                 140                 


Ile Asn Val Pro Ser Leu Cys Gly Met Asp His Thr Glu Lys Arg Gly 
145                 150                 155                 160 


Arg Ile Tyr Leu Lys Ala Glu Val Ala Asp Glu Lys Leu His Val Thr 
                165                 170                 175     


Val Arg Asp Ala Lys Asn Leu Ile Pro Met Asp Pro Asn Gly Leu Ser 
            180                 185                 190         


Asp Pro Tyr Val Lys Leu Lys Leu Ile Pro Asp Pro Lys Asn Glu Ser 
        195                 200                 205             


Lys Gln Lys Thr Lys Thr Ile Arg Ser Thr Leu Asn Pro Gln Trp Asn 
    210                 215                 220                 


Glu Ser Phe Thr Phe Lys Leu Lys Pro Ser Asp Lys Asp Arg Arg Leu 
225                 230                 235                 240 


Ser Val Glu Ile Trp Asp Trp Asp Arg Thr Thr Arg Asn Asp Phe Met 
                245                 250                 255     


Gly Ser Leu Ser Phe Gly Val Ser Glu Leu Met Lys Met Pro Ala Ser 
            260                 265                 270         


Gly Trp Tyr Lys Leu Leu Asn Gln Glu Glu Gly Glu Tyr Tyr Asn Val 
        275                 280                 285             


Pro Ile Pro Glu Gly Asp Glu Glu Gly Asn Met Glu Leu Arg Gln Lys 
    290                 295                 300                 


Phe Glu Lys Ala Lys Leu Gly Pro Ala Gly Asn Lys Val Ile Ser Pro 
305                 310                 315                 320 


Ser Glu Asp Arg Lys Gln Pro Ser Asn Asn Leu Asp Arg Val Lys Leu 
                325                 330                 335     


Thr Asp Phe Asn Phe Leu Met Val Leu Gly Lys Gly Ser Phe Gly Lys 
            340                 345                 350         


Val Met Leu Ala Asp Arg Lys Gly Thr Glu Glu Leu Tyr Ala Ile Lys 
        355                 360                 365             


Ile Leu Lys Lys Asp Val Val Ile Gln Asp Asp Asp Val Glu Cys Thr 
    370                 375                 380                 


Met Val Glu Lys Arg Val Leu Ala Leu Leu Asp Lys Pro Pro Phe Leu 
385                 390                 395                 400 


Thr Gln Leu His Ser Cys Phe Gln Thr Val Asp Arg Leu Tyr Phe Val 
                405                 410                 415     


Met Glu Tyr Val Asn Gly Gly Asp Leu Met Tyr His Ile Gln Gln Val 
            420                 425                 430         


Gly Lys Phe Lys Glu Pro Gln Ala Val Phe Tyr Ala Ala Glu Ile Ser 
        435                 440                 445             


Ile Gly Leu Phe Phe Leu His Lys Arg Gly Ile Ile Tyr Arg Asp Leu 
    450                 455                 460                 


Lys Leu Asp Asn Val Met Leu Asp Ser Glu Gly His Ile Lys Ile Ala 
465                 470                 475                 480 


Asp Phe Gly Met Cys Lys Glu His Met Met Asp Gly Val Thr Thr Arg 
                485                 490                 495     


Thr Phe Cys Gly Thr Pro Asp Tyr Ile Ala Pro Glu Ile Ile Ala Tyr 
            500                 505                 510         


Gln Pro Tyr Gly Lys Ser Val Asp Trp Trp Ala Tyr Gly Val Leu Leu 
        515                 520                 525             


Tyr Glu Met Leu Ala Gly Gln Pro Pro Phe Asp Gly Glu Asp Glu Asp 
    530                 535                 540                 


Glu Leu Phe Gln Ser Ile Met Glu His Asn Val Ser Tyr Pro Lys Ser 
545                 550                 555                 560 


Leu Ser Lys Glu Ala Val Ser Ile Cys Lys Gly Leu Met Thr Lys His 
                565                 570                 575     


Pro Ala Lys Arg Leu Gly Cys Gly Pro Glu Gly Glu Arg Asp Val Arg 
            580                 585                 590         


Glu His Ala Phe Phe Arg Arg Ile Asp Trp Glu Lys Leu Glu Asn Arg 
        595                 600                 605             


Glu Ile Gln Pro Pro Phe Lys Pro Lys Val Cys Gly Lys Gly Ala Glu 
    610                 615                 620                 


Asn Phe Asp Lys Phe Phe Thr Arg Gly Gln Pro Val Leu Thr Pro Pro 
625                 630                 635                 640 


Asp Gln Leu Val Ile Ala Asn Ile Asp Gln Ser Asp Phe Glu Gly Phe 
                645                 650                 655     


Ser Tyr Val Asn Pro Gln Phe Val His Pro Ile Leu Gln Ser Ala Val 
            660                 665                 670         


<210>  4158
<211>  1556
<212>  PRT
<213>  homo sapiens

<400>  4158

Met Pro Leu Leu His Arg Lys Pro Phe Val Arg Gln Lys Pro Pro Ala 
1               5                   10                  15      


Asp Leu Arg Pro Asp Glu Glu Val Phe Tyr Cys Lys Val Thr Asn Glu 
            20                  25                  30          


Ile Phe Arg His Tyr Asp Asp Phe Phe Glu Arg Thr Ile Leu Cys Asn 
        35                  40                  45              


Ser Leu Val Trp Ser Cys Ala Val Thr Gly Arg Pro Gly Leu Thr Tyr 
    50                  55                  60                  


Gln Glu Ala Leu Glu Ser Glu Lys Lys Ala Arg Gln Asn Leu Gln Ser 
65                  70                  75                  80  


Phe Pro Glu Pro Leu Ile Ile Pro Val Leu Tyr Leu Thr Ser Leu Thr 
                85                  90                  95      


His Arg Ser Arg Leu His Glu Ile Cys Asp Asp Ile Phe Ala Tyr Val 
            100                 105                 110         


Lys Asp Arg Tyr Phe Val Glu Glu Thr Val Glu Val Ile Arg Asn Asn 
        115                 120                 125             


Gly Ala Arg Leu Gln Cys Arg Ile Leu Glu Val Leu Pro Pro Ser His 
    130                 135                 140                 


Gln Asn Gly Phe Ala Asn Gly His Val Asn Ser Val Asp Gly Glu Thr 
145                 150                 155                 160 


Ile Ile Ile Ser Asp Ser Asp Asp Ser Glu Thr Gln Ser Cys Ser Phe 
                165                 170                 175     


Gln Asn Gly Lys Lys Lys Asp Ala Ile Asp Pro Leu Leu Phe Lys Tyr 
            180                 185                 190         


Lys Val Gln Pro Thr Lys Lys Glu Leu His Glu Ser Ala Ile Val Lys 
        195                 200                 205             


Ala Thr Gln Ile Ser Arg Arg Lys His Leu Phe Ser Arg Asp Lys Leu 
    210                 215                 220                 


Lys Leu Phe Leu Lys Gln His Cys Glu Pro Gln Asp Gly Val Ile Lys 
225                 230                 235                 240 


Ile Lys Ala Ser Ser Leu Ser Thr Tyr Lys Ile Ala Glu Gln Asp Phe 
                245                 250                 255     


Ser Tyr Phe Phe Pro Asp Asp Pro Pro Thr Phe Ile Phe Ser Pro Ala 
            260                 265                 270         


Asn Arg Arg Arg Gly Arg Pro Pro Lys Arg Ile His Ile Ser Gln Glu 
        275                 280                 285             


Asp Asn Val Ala Asn Lys Gln Thr Leu Ala Ser Tyr Arg Ser Lys Ala 
    290                 295                 300                 


Thr Lys Glu Arg Asp Lys Leu Leu Lys Gln Glu Glu Met Lys Ser Leu 
305                 310                 315                 320 


Ala Phe Glu Lys Ala Lys Leu Lys Arg Glu Lys Ala Asp Ala Leu Glu 
                325                 330                 335     


Ala Lys Lys Lys Glu Lys Glu Asp Lys Glu Lys Lys Arg Glu Glu Leu 
            340                 345                 350         


Lys Lys Ile Val Glu Glu Glu Arg Leu Lys Lys Lys Glu Glu Lys Glu 
        355                 360                 365             


Arg Leu Lys Val Glu Arg Glu Lys Glu Arg Glu Lys Leu Arg Glu Glu 
    370                 375                 380                 


Lys Arg Lys Tyr Val Glu Tyr Leu Lys Gln Trp Ser Lys Pro Arg Glu 
385                 390                 395                 400 


Asp Met Glu Cys Asp Asp Leu Lys Glu Leu Pro Glu Pro Thr Pro Val 
                405                 410                 415     


Lys Thr Arg Leu Pro Pro Glu Ile Phe Gly Asp Ala Leu Met Val Leu 
            420                 425                 430         


Glu Phe Leu Asn Ala Phe Gly Glu Leu Phe Asp Leu Gln Asp Glu Phe 
        435                 440                 445             


Pro Asp Gly Val Thr Leu Glu Val Leu Glu Glu Ala Leu Val Gly Asn 
    450                 455                 460                 


Asp Ser Glu Gly Pro Leu Cys Glu Leu Leu Phe Phe Phe Leu Thr Ala 
465                 470                 475                 480 


Ile Phe Gln Ala Ile Ala Glu Glu Glu Glu Glu Val Ala Lys Glu Gln 
                485                 490                 495     


Leu Thr Asp Ala Asp Thr Lys Asp Leu Thr Glu Ala Leu Asp Glu Asp 
            500                 505                 510         


Ala Asp Pro Thr Lys Ser Ala Leu Ser Ala Val Ala Ser Leu Ala Ala 
        515                 520                 525             


Ala Trp Pro Gln Leu His Gln Gly Cys Ser Leu Lys Ser Leu Asp Leu 
    530                 535                 540                 


Asp Ser Cys Thr Leu Ser Glu Ile Leu Arg Leu His Ile Leu Ala Ser 
545                 550                 555                 560 


Gly Ala Asp Val Thr Ser Ala Asn Ala Lys Tyr Arg Tyr Gln Lys Arg 
                565                 570                 575     


Gly Gly Phe Asp Ala Thr Asp Asp Ala Cys Met Glu Leu Arg Leu Ser 
            580                 585                 590         


Asn Pro Ser Leu Val Lys Lys Leu Ser Ser Thr Ser Val Tyr Asp Leu 
        595                 600                 605             


Thr Pro Gly Glu Lys Met Lys Ile Leu His Ala Leu Cys Gly Lys Leu 
    610                 615                 620                 


Leu Thr Leu Val Ser Thr Arg Asp Phe Ile Glu Asp Tyr Val Asp Ile 
625                 630                 635                 640 


Leu Arg Gln Ala Lys Gln Glu Phe Arg Glu Leu Lys Ala Glu Gln His 
                645                 650                 655     


Arg Lys Glu Arg Glu Glu Ala Ala Ala Arg Ile Arg Lys Arg Lys Glu 
            660                 665                 670         


Glu Lys Leu Lys Glu Gln Glu Gln Lys Met Lys Glu Lys Gln Glu Lys 
        675                 680                 685             


Leu Lys Glu Asp Glu Gln Arg Asn Ser Thr Ala Asp Ile Ser Ile Gly 
    690                 695                 700                 


Glu Glu Glu Arg Glu Asp Phe Asp Thr Ser Ile Glu Ser Lys Asp Thr 
705                 710                 715                 720 


Glu Gln Lys Glu Leu Asp Gln Asp Met Val Thr Glu Asp Glu Asp Asp 
                725                 730                 735     


Pro Gly Ser His Lys Arg Gly Arg Arg Gly Lys Arg Gly Gln Asn Gly 
            740                 745                 750         


Phe Lys Glu Phe Thr Arg Gln Glu Gln Ile Asn Cys Val Thr Arg Glu 
        755                 760                 765             


Pro Leu Thr Ala Asp Glu Glu Glu Ala Leu Lys Gln Glu His Gln Arg 
    770                 775                 780                 


Lys Glu Lys Glu Leu Leu Glu Lys Ile Gln Ser Ala Ile Ala Cys Thr 
785                 790                 795                 800 


Asn Ile Phe Pro Leu Gly Arg Asp Arg Met Tyr Arg Arg Tyr Trp Ile 
                805                 810                 815     


Phe Pro Ser Ile Pro Gly Leu Phe Ile Glu Glu Asp Tyr Ser Gly Leu 
            820                 825                 830         


Thr Glu Asp Met Leu Leu Pro Arg Pro Ser Ser Phe Gln Asn Asn Val 
        835                 840                 845             


Gln Ser Gln Asp Pro Gln Val Ser Thr Lys Thr Gly Glu Pro Leu Met 
    850                 855                 860                 


Ser Glu Ser Thr Ser Asn Ile Asp Gln Gly Pro Arg Asp His Ser Val 
865                 870                 875                 880 


Gln Leu Pro Lys Pro Val His Lys Pro Asn Arg Trp Cys Phe Tyr Ser 
                885                 890                 895     


Ser Cys Glu Gln Leu Asp Gln Leu Ile Glu Ala Leu Asn Ser Arg Gly 
            900                 905                 910         


His Arg Glu Ser Ala Leu Lys Glu Thr Leu Leu Gln Glu Lys Ser Arg 
        915                 920                 925             


Ile Cys Ala Gln Leu Ala Arg Phe Ser Glu Glu Lys Phe His Phe Ser 
    930                 935                 940                 


Asp Lys Pro Gln Pro Asp Ser Lys Pro Thr Tyr Ser Arg Gly Arg Ser 
945                 950                 955                 960 


Ser Asn Ala Tyr Asp Pro Ser Gln Met Cys Ala Glu Lys Gln Leu Glu 
                965                 970                 975     


Leu Arg Leu Arg Asp Phe Leu Leu Asp Ile Glu Asp Arg Ile Tyr Gln 
            980                 985                 990         


Gly Thr Leu Gly Ala Ile Lys Val  Thr Asp Arg His Ile  Trp Arg Ser 
        995                 1000                 1005             


Ala Leu  Glu Ser Gly Arg Tyr  Glu Leu Leu Ser Glu  Glu Asn Lys 
    1010                 1015                 1020             


Glu Asn  Gly Ile Ile Lys Thr  Val Asn Glu Asp Val  Glu Glu Met 
    1025                 1030                 1035             


Glu Ile  Asp Glu Gln Thr Lys  Val Ile Val Lys Asp  Arg Leu Leu 
    1040                 1045                 1050             


Gly Ile  Lys Thr Glu Thr Pro  Ser Thr Val Ser Thr  Asn Ala Ser 
    1055                 1060                 1065             


Thr Pro  Gln Ser Val Ser Ser  Val Val His Tyr Leu  Ala Met Ala 
    1070                 1075                 1080             


Leu Phe  Gln Ile Glu Gln Gly  Ile Glu Arg Arg Phe  Leu Lys Ala 
    1085                 1090                 1095             


Pro Leu  Asp Ala Ser Asp Ser  Gly Arg Ser Tyr Lys  Thr Val Leu 
    1100                 1105                 1110             


Asp Arg  Trp Arg Glu Ser Leu  Leu Ser Ser Ala Ser  Leu Ser Gln 
    1115                 1120                 1125             


Val Phe  Leu His Leu Ser Thr  Leu Asp Arg Ser Val  Ile Trp Ser 
    1130                 1135                 1140             


Lys Ser  Ile Leu Asn Ala Arg  Cys Lys Ile Cys Arg  Lys Lys Gly 
    1145                 1150                 1155             


Asp Ala  Glu Asn Met Val Leu  Cys Asp Gly Cys Asp  Arg Gly His 
    1160                 1165                 1170             


His Thr  Tyr Cys Val Arg Pro  Lys Leu Lys Thr Val  Pro Glu Gly 
    1175                 1180                 1185             


Asp Trp  Phe Cys Pro Glu Cys  Arg Pro Lys Gln Arg  Ser Arg Arg 
    1190                 1195                 1200             


Leu Ser  Ser Arg Gln Arg Pro  Ser Leu Glu Ser Asp  Glu Asp Val 
    1205                 1210                 1215             


Glu Asp  Ser Met Gly Gly Glu  Asp Asp Glu Val Asp  Gly Asp Glu 
    1220                 1225                 1230             


Glu Glu  Gly Gln Ser Glu Glu  Glu Glu Tyr Glu Val  Glu Gln Asp 
    1235                 1240                 1245             


Glu Asp  Asp Ser Gln Glu Glu  Glu Glu Val Ser Leu  Pro Lys Arg 
    1250                 1255                 1260             


Gly Arg  Pro Gln Val Arg Leu  Pro Val Lys Thr Arg  Gly Lys Leu 
    1265                 1270                 1275             


Ser Ser  Ser Phe Ser Ser Arg  Gly Gln Gln Gln Glu  Pro Gly Arg 
    1280                 1285                 1290             


Tyr Pro  Ser Arg Ser Gln Gln  Ser Thr Pro Lys Thr  Thr Val Ser 
    1295                 1300                 1305             


Ser Lys  Thr Gly Arg Ser Leu  Arg Lys Ile Asn Ser  Ala Pro Pro 
    1310                 1315                 1320             


Thr Glu  Thr Lys Ser Leu Arg  Ile Ala Ser Arg Ser  Thr Arg His 
    1325                 1330                 1335             


Ser His  Gly Pro Leu Gln Ala  Asp Val Phe Val Glu  Leu Leu Ser 
    1340                 1345                 1350             


Pro Arg  Arg Lys Arg Arg Gly  Arg Lys Ser Ala Asn  Asn Thr Pro 
    1355                 1360                 1365             


Glu Asn  Ser Pro Asn Phe Pro  Asn Phe Arg Val Ile  Ala Thr Lys 
    1370                 1375                 1380             


Ser Ser  Glu Gln Ser Arg Ser  Val Asn Ile Ala Ser  Lys Leu Ser 
    1385                 1390                 1395             


Leu Gln  Glu Ser Glu Ser Lys  Arg Arg Cys Arg Lys  Arg Gln Ser 
    1400                 1405                 1410             


Pro Glu  Pro Ser Pro Val Thr  Leu Gly Arg Arg Ser  Ser Gly Arg 
    1415                 1420                 1425             


Gln Gly  Gly Val His Glu Leu  Ser Ala Phe Glu Gln  Leu Val Val 
    1430                 1435                 1440             


Glu Leu  Val Arg His Asp Asp  Ser Trp Pro Phe Leu  Lys Leu Val 
    1445                 1450                 1455             


Ser Lys  Ile Gln Val Pro Asp  Tyr Tyr Asp Ile Ile  Lys Lys Pro 
    1460                 1465                 1470             


Ile Ala  Leu Asn Ile Ile Arg  Glu Lys Val Asn Lys  Cys Glu Tyr 
    1475                 1480                 1485             


Lys Leu  Ala Ser Glu Phe Ile  Asp Asp Ile Glu Leu  Met Phe Ser 
    1490                 1495                 1500             


Asn Cys  Phe Glu Tyr Asn Pro  Arg Asn Thr Ser Glu  Ala Lys Ala 
    1505                 1510                 1515             


Gly Thr  Arg Leu Gln Ala Phe  Phe His Ile Gln Ala  Gln Lys Leu 
    1520                 1525                 1530             


Gly Leu  His Val Thr Pro Ser  Asn Val Asp Gln Val  Ser Thr Pro 
    1535                 1540                 1545             


Pro Ala  Ala Lys Lys Ser Arg  Ile 
    1550                 1555     


<210>  4159
<211>  614
<212>  PRT
<213>  homo sapiens

<400>  4159

Met Asn Lys Leu Asn Phe His Asn Asn Arg Val Met Gln Asp Arg Arg 
1               5                   10                  15      


Ser Val Cys Ile Phe Leu Pro Asn Asp Glu Ser Leu Asn Ile Ile Ile 
            20                  25                  30          


Asn Val Lys Ile Leu Cys His Gln Leu Leu Val Gln Val Cys Asp Leu 
        35                  40                  45              


Leu Arg Leu Lys Asp Cys His Leu Phe Gly Leu Ser Val Ile Gln Asn 
    50                  55                  60                  


Asn Glu His Val Tyr Met Glu Leu Ser Gln Lys Leu Tyr Lys Tyr Cys 
65                  70                  75                  80  


Pro Lys Glu Trp Lys Lys Glu Ala Ser Lys Gly Ile Asp Gln Phe Gly 
                85                  90                  95      


Pro Pro Met Ile Ile His Phe Arg Val Gln Tyr Tyr Val Glu Asn Gly 
            100                 105                 110         


Arg Leu Ile Ser Asp Arg Ala Ala Arg Tyr Tyr Tyr Tyr Trp His Leu 
        115                 120                 125             


Arg Lys Gln Val Leu His Ser Gln Cys Val Leu Arg Glu Glu Ala Tyr 
    130                 135                 140                 


Phe Leu Leu Ala Ala Phe Ala Leu Gln Ala Asp Leu Gly Asn Phe Lys 
145                 150                 155                 160 


Arg Asn Lys His Tyr Gly Lys Tyr Phe Glu Pro Glu Ala Tyr Phe Pro 
                165                 170                 175     


Ser Trp Val Val Ser Lys Arg Gly Lys Asp Tyr Ile Leu Lys His Ile 
            180                 185                 190         


Pro Asn Met His Lys Asp Gln Phe Ala Leu Thr Ala Ser Glu Ala His 
        195                 200                 205             


Leu Lys Tyr Ile Lys Glu Ala Val Arg Leu Asp Asp Val Ala Val His 
    210                 215                 220                 


Tyr Tyr Arg Leu Tyr Lys Asp Lys Arg Glu Ile Glu Ala Ser Leu Thr 
225                 230                 235                 240 


Leu Gly Leu Thr Met Arg Gly Ile Gln Ile Phe Gln Asn Leu Asp Glu 
                245                 250                 255     


Glu Lys Gln Leu Leu Tyr Asp Phe Pro Trp Thr Asn Val Gly Lys Leu 
            260                 265                 270         


Val Phe Val Gly Lys Lys Phe Glu Ile Leu Pro Asp Gly Leu Pro Ser 
        275                 280                 285             


Ala Arg Lys Leu Ile Tyr Tyr Thr Gly Cys Pro Met Arg Ser Arg His 
    290                 295                 300                 


Leu Leu Gln Leu Leu Ser Asn Ser His Arg Leu Tyr Met Asn Leu Gln 
305                 310                 315                 320 


Pro Val Leu Arg His Ile Arg Lys Leu Glu Glu Asn Glu Glu Lys Lys 
                325                 330                 335     


Gln Tyr Arg Glu Ser Tyr Ile Ser Asp Asn Leu Asp Leu Asp Met Asp 
            340                 345                 350         


Gln Leu Glu Lys Arg Ser Arg Ala Ser Gly Ser Ser Ala Gly Ser Met 
        355                 360                 365             


Lys His Lys Arg Leu Ser Arg His Ser Thr Ala Ser His Ser Ser Ser 
    370                 375                 380                 


His Thr Ser Gly Ile Glu Ala Asp Thr Lys Pro Arg Asp Thr Gly Pro 
385                 390                 395                 400 


Glu Asp Ser Tyr Ser Ser Ser Ala Ile His Arg Lys Leu Lys Thr Cys 
                405                 410                 415     


Ser Ser Met Thr Ser His Gly Ser Ser His Thr Ser Gly Val Glu Ser 
            420                 425                 430         


Gly Gly Lys Asp Arg Leu Glu Glu Asp Leu Gln Asp Asp Glu Ile Glu 
        435                 440                 445             


Met Leu Val Asp Asp Pro Arg Asp Leu Glu Gln Met Asn Glu Glu Ser 
    450                 455                 460                 


Leu Glu Val Ser Pro Asp Met Cys Ile Tyr Ile Thr Glu Asp Met Leu 
465                 470                 475                 480 


Met Ser Arg Lys Leu Asn Gly His Ser Gly Leu Ile Val Lys Glu Ile 
                485                 490                 495     


Gly Ser Ser Thr Ser Ser Ser Ser Glu Thr Val Val Lys Leu Arg Gly 
            500                 505                 510         


Gln Ser Thr Asp Ser Leu Pro Gln Thr Ile Cys Arg Lys Pro Lys Thr 
        515                 520                 525             


Ser Thr Asp Arg His Ser Leu Ser Leu Asp Asp Ile Arg Leu Tyr Gln 
    530                 535                 540                 


Lys Asp Phe Leu Arg Ile Ala Gly Leu Cys Gln Asp Thr Ala Gln Ser 
545                 550                 555                 560 


Tyr Thr Phe Gly Cys Gly His Glu Leu Asp Glu Glu Gly Leu Tyr Cys 
                565                 570                 575     


Asn Ser Cys Leu Ala Gln Gln Cys Ile Asn Ile Gln Asp Ala Phe Pro 
            580                 585                 590         


Val Lys Arg Thr Ser Lys Tyr Phe Ser Leu Asp Leu Thr His Asp Glu 
        595                 600                 605             


Val Pro Glu Phe Val Val 
    610                 


<210>  4160
<211>  240
<212>  PRT
<213>  homo sapiens

<400>  4160

Met Glu Asp Tyr Thr Lys Ile Glu Lys Ile Gly Glu Gly Thr Tyr Gly 
1               5                   10                  15      


Val Val Tyr Lys Gly Arg His Lys Thr Thr Gly Gln Val Val Ala Met 
            20                  25                  30          


Lys Lys Ile Arg Leu Glu Ser Glu Glu Glu Gly Val Pro Ser Thr Ala 
        35                  40                  45              


Ile Arg Glu Ile Ser Leu Leu Lys Glu Leu Arg His Pro Asn Ile Val 
    50                  55                  60                  


Ser Leu Gln Asp Val Leu Met Gln Asp Ser Arg Leu Tyr Leu Ile Phe 
65                  70                  75                  80  


Glu Phe Leu Ser Met Asp Leu Lys Lys Tyr Leu Asp Ser Ile Pro Pro 
                85                  90                  95      


Gly Gln Tyr Met Asp Ser Ser Leu Val Lys Val Val Thr Leu Trp Tyr 
            100                 105                 110         


Arg Ser Pro Glu Val Leu Leu Gly Ser Ala Arg Tyr Ser Thr Pro Val 
        115                 120                 125             


Asp Ile Trp Ser Ile Gly Thr Ile Phe Ala Glu Leu Ala Thr Lys Lys 
    130                 135                 140                 


Pro Leu Phe His Gly Asp Ser Glu Ile Asp Gln Leu Phe Arg Ile Phe 
145                 150                 155                 160 


Arg Ala Leu Gly Thr Pro Asn Asn Glu Val Trp Pro Glu Val Glu Ser 
                165                 170                 175     


Leu Gln Asp Tyr Lys Asn Thr Phe Pro Lys Trp Lys Pro Gly Ser Leu 
            180                 185                 190         


Ala Ser His Val Lys Asn Leu Asp Glu Asn Gly Leu Asp Leu Leu Ser 
        195                 200                 205             


Lys Met Leu Ile Tyr Asp Pro Ala Lys Arg Ile Ser Gly Lys Met Ala 
    210                 215                 220                 


Leu Asn His Pro Tyr Phe Asn Asp Leu Asp Asn Gln Ile Lys Lys Met 
225                 230                 235                 240 


<210>  4161
<211>  742
<212>  PRT
<213>  homo sapiens

<400>  4161

Met Asp Ser Lys Glu Ser Leu Thr Pro Gly Arg Glu Glu Asn Pro Ser 
1               5                   10                  15      


Ser Val Leu Ala Gln Glu Arg Gly Asp Val Met Asp Phe Tyr Lys Thr 
            20                  25                  30          


Leu Arg Gly Gly Ala Thr Val Lys Val Ser Ala Ser Ser Pro Ser Leu 
        35                  40                  45              


Ala Val Ala Ser Gln Ser Asp Ser Lys Gln Arg Arg Leu Leu Val Asp 
    50                  55                  60                  


Phe Pro Lys Gly Ser Val Ser Asn Ala Gln Gln Pro Asp Leu Ser Lys 
65                  70                  75                  80  


Ala Val Ser Leu Ser Met Gly Leu Tyr Met Gly Glu Thr Glu Thr Lys 
                85                  90                  95      


Val Met Gly Asn Asp Leu Gly Phe Pro Gln Gln Gly Gln Ile Ser Leu 
            100                 105                 110         


Ser Ser Gly Glu Thr Asp Leu Lys Leu Leu Glu Glu Ser Ile Ala Asn 
        115                 120                 125             


Leu Asn Arg Ser Thr Ser Val Pro Glu Asn Pro Lys Ser Ser Ala Ser 
    130                 135                 140                 


Thr Ala Val Ser Ala Ala Pro Thr Glu Lys Glu Phe Pro Lys Thr His 
145                 150                 155                 160 


Ser Asp Val Ser Ser Glu Gln Gln His Leu Lys Gly Gln Thr Gly Thr 
                165                 170                 175     


Asn Gly Gly Asn Val Lys Leu Tyr Thr Thr Asp Gln Ser Thr Phe Asp 
            180                 185                 190         


Ile Leu Gln Asp Leu Glu Phe Ser Ser Gly Ser Pro Gly Lys Glu Thr 
        195                 200                 205             


Asn Glu Ser Pro Trp Arg Ser Asp Leu Leu Ile Asp Glu Asn Cys Leu 
    210                 215                 220                 


Leu Ser Pro Leu Ala Gly Glu Asp Asp Ser Phe Leu Leu Glu Gly Asn 
225                 230                 235                 240 


Ser Asn Glu Asp Cys Lys Pro Leu Ile Leu Pro Asp Thr Lys Pro Lys 
                245                 250                 255     


Ile Lys Asp Asn Gly Asp Leu Val Leu Ser Ser Pro Ser Asn Val Thr 
            260                 265                 270         


Leu Pro Gln Val Lys Thr Glu Lys Glu Asp Phe Ile Glu Leu Cys Thr 
        275                 280                 285             


Pro Gly Val Ile Lys Gln Glu Lys Leu Gly Thr Val Tyr Cys Gln Ala 
    290                 295                 300                 


Ser Phe Pro Gly Ala Asn Ile Ile Gly Asn Lys Met Ser Ala Ile Ser 
305                 310                 315                 320 


Val His Gly Val Ser Thr Ser Gly Gly Gln Met Tyr His Tyr Asp Met 
                325                 330                 335     


Asn Thr Ala Ser Leu Ser Gln Gln Gln Asp Gln Lys Pro Ile Phe Asn 
            340                 345                 350         


Val Ile Pro Pro Ile Pro Val Gly Ser Glu Asn Trp Asn Arg Cys Gln 
        355                 360                 365             


Gly Ser Gly Asp Asp Asn Leu Thr Ser Leu Gly Thr Leu Asn Phe Pro 
    370                 375                 380                 


Gly Arg Thr Val Phe Ser Asn Gly Tyr Ser Ser Pro Ser Met Arg Pro 
385                 390                 395                 400 


Asp Val Ser Ser Pro Pro Ser Ser Ser Ser Thr Ala Thr Thr Gly Pro 
                405                 410                 415     


Pro Pro Lys Leu Cys Leu Val Cys Ser Asp Glu Ala Ser Gly Cys His 
            420                 425                 430         


Tyr Gly Val Leu Thr Cys Gly Ser Cys Lys Val Phe Phe Lys Arg Ala 
        435                 440                 445             


Val Glu Gly Gln His Asn Tyr Leu Cys Ala Gly Arg Asn Asp Cys Ile 
    450                 455                 460                 


Ile Asp Lys Ile Arg Arg Lys Asn Cys Pro Ala Cys Arg Tyr Arg Lys 
465                 470                 475                 480 


Cys Leu Gln Ala Gly Met Asn Leu Glu Ala Arg Lys Thr Lys Lys Lys 
                485                 490                 495     


Ile Lys Gly Ile Gln Gln Ala Thr Thr Gly Val Ser Gln Glu Thr Ser 
            500                 505                 510         


Glu Asn Pro Gly Asn Lys Thr Ile Val Pro Ala Thr Leu Pro Gln Leu 
        515                 520                 525             


Thr Pro Thr Leu Val Ser Leu Leu Glu Val Ile Glu Pro Glu Val Leu 
    530                 535                 540                 


Tyr Ala Gly Tyr Asp Ser Ser Val Pro Asp Ser Thr Trp Arg Ile Met 
545                 550                 555                 560 


Thr Thr Leu Asn Met Leu Gly Gly Arg Gln Val Ile Ala Ala Val Lys 
                565                 570                 575     


Trp Ala Lys Ala Ile Pro Gly Phe Arg Asn Leu His Leu Asp Asp Gln 
            580                 585                 590         


Met Thr Leu Leu Gln Tyr Ser Trp Met Phe Leu Met Ala Phe Ala Leu 
        595                 600                 605             


Gly Trp Arg Ser Tyr Arg Gln Ser Ser Ala Asn Leu Leu Cys Phe Ala 
    610                 615                 620                 


Pro Asp Leu Ile Ile Asn Glu Gln Arg Met Thr Leu Pro Cys Met Tyr 
625                 630                 635                 640 


Asp Gln Cys Lys His Met Leu Tyr Val Ser Ser Glu Leu His Arg Leu 
                645                 650                 655     


Gln Val Ser Tyr Glu Glu Tyr Leu Cys Met Lys Thr Leu Leu Leu Leu 
            660                 665                 670         


Ser Ser Val Pro Lys Asp Gly Leu Lys Ser Gln Glu Leu Phe Asp Glu 
        675                 680                 685             


Ile Arg Met Thr Tyr Ile Lys Glu Leu Gly Lys Ala Ile Val Lys Arg 
    690                 695                 700                 


Glu Gly Asn Ser Ser Gln Asn Trp Gln Arg Phe Tyr Gln Leu Thr Lys 
705                 710                 715                 720 


Leu Leu Asp Ser Met His Glu Asn Val Met Trp Leu Lys Pro Glu Ser 
                725                 730                 735     


Thr Ser His Thr Leu Ile 
            740         


<210>  4162
<211>  1524
<212>  PRT
<213>  homo sapiens

<400>  4162

Met Pro Leu Leu His Arg Lys Pro Phe Val Arg Gln Lys Pro Pro Ala 
1               5                   10                  15      


Asp Leu Arg Pro Asp Glu Glu Val Phe Tyr Cys Lys Val Thr Asn Glu 
            20                  25                  30          


Ile Phe Arg His Tyr Asp Asp Phe Phe Glu Arg Thr Ile Leu Cys Asn 
        35                  40                  45              


Ser Leu Val Trp Ser Cys Ala Val Thr Gly Arg Pro Gly Leu Thr Tyr 
    50                  55                  60                  


Gln Glu Ala Leu Glu Ser Glu Lys Lys Ala Arg Gln Asn Leu Gln Ser 
65                  70                  75                  80  


Phe Pro Glu Pro Leu Ile Ile Pro Val Leu Tyr Leu Thr Ser Leu Thr 
                85                  90                  95      


His Arg Ser Arg Leu His Glu Ile Cys Asp Asp Ile Phe Ala Tyr Val 
            100                 105                 110         


Lys Asp Arg Tyr Phe Val Glu Glu Thr Val Glu Val Ile Arg Asn Asn 
        115                 120                 125             


Gly Ala Arg Leu Gln Cys Arg Ile Leu Glu Val Leu Pro Pro Ser His 
    130                 135                 140                 


Gln Asn Gly Phe Ala Asn Gly His Val Asn Ser Val Asp Gly Glu Thr 
145                 150                 155                 160 


Ile Ile Ile Ser Asp Ser Asp Asp Ser Glu Thr Gln Ser Cys Ser Phe 
                165                 170                 175     


Gln Asn Gly Lys Lys Lys Asp Ala Ile Asp Pro Leu Leu Phe Lys Tyr 
            180                 185                 190         


Lys Val Gln Pro Thr Lys Lys Glu Leu His Glu Ser Ala Ile Val Lys 
        195                 200                 205             


Ala Thr Gln Ile Ser Arg Arg Lys His Leu Phe Ser Arg Asp Lys Leu 
    210                 215                 220                 


Lys Leu Phe Leu Lys Gln His Cys Glu Pro Gln Asp Gly Val Ile Lys 
225                 230                 235                 240 


Ile Lys Ala Ser Ser Leu Ser Thr Tyr Lys Ile Ala Glu Gln Asp Phe 
                245                 250                 255     


Ser Tyr Phe Phe Pro Asp Asp Pro Pro Thr Phe Ile Phe Ser Pro Ala 
            260                 265                 270         


Asn Arg Arg Arg Gly Arg Pro Pro Lys Arg Ile His Ile Ser Gln Glu 
        275                 280                 285             


Asp Asn Val Ala Asn Lys Gln Thr Leu Ala Ser Tyr Arg Ser Lys Ala 
    290                 295                 300                 


Thr Lys Glu Arg Asp Lys Leu Leu Lys Gln Glu Glu Met Lys Ser Leu 
305                 310                 315                 320 


Ala Phe Glu Lys Ala Lys Leu Lys Arg Glu Lys Ala Asp Ala Leu Glu 
                325                 330                 335     


Ala Lys Lys Lys Glu Lys Glu Asp Lys Glu Lys Lys Arg Glu Glu Leu 
            340                 345                 350         


Lys Lys Ile Val Glu Glu Glu Arg Leu Lys Lys Lys Glu Glu Lys Glu 
        355                 360                 365             


Arg Leu Lys Val Glu Arg Glu Lys Glu Arg Glu Lys Leu Arg Glu Glu 
    370                 375                 380                 


Lys Arg Lys Tyr Val Glu Tyr Leu Lys Gln Trp Ser Lys Pro Arg Glu 
385                 390                 395                 400 


Asp Met Glu Cys Asp Asp Leu Lys Glu Leu Pro Glu Pro Thr Pro Val 
                405                 410                 415     


Lys Thr Arg Leu Pro Pro Glu Ile Phe Gly Asp Ala Leu Met Val Leu 
            420                 425                 430         


Glu Phe Leu Asn Ala Phe Gly Glu Leu Phe Asp Leu Gln Asp Glu Phe 
        435                 440                 445             


Pro Asp Gly Val Thr Leu Glu Val Leu Glu Glu Ala Leu Val Gly Asn 
    450                 455                 460                 


Asp Ser Glu Gly Pro Leu Cys Glu Leu Leu Phe Phe Phe Leu Thr Ala 
465                 470                 475                 480 


Ile Phe Gln Ala Ile Ala Glu Glu Glu Glu Glu Val Ala Lys Glu Gln 
                485                 490                 495     


Leu Thr Asp Ala Asp Thr Lys Gly Cys Ser Leu Lys Ser Leu Asp Leu 
            500                 505                 510         


Asp Ser Cys Thr Leu Ser Glu Ile Leu Arg Leu His Ile Leu Ala Ser 
        515                 520                 525             


Gly Ala Asp Val Thr Ser Ala Asn Ala Lys Tyr Arg Tyr Gln Lys Arg 
    530                 535                 540                 


Gly Gly Phe Asp Ala Thr Asp Asp Ala Cys Met Glu Leu Arg Leu Ser 
545                 550                 555                 560 


Asn Pro Ser Leu Val Lys Lys Leu Ser Ser Thr Ser Val Tyr Asp Leu 
                565                 570                 575     


Thr Pro Gly Glu Lys Met Lys Ile Leu His Ala Leu Cys Gly Lys Leu 
            580                 585                 590         


Leu Thr Leu Val Ser Thr Arg Asp Phe Ile Glu Asp Tyr Val Asp Ile 
        595                 600                 605             


Leu Arg Gln Ala Lys Gln Glu Phe Arg Glu Leu Lys Ala Glu Gln His 
    610                 615                 620                 


Arg Lys Glu Arg Glu Glu Ala Ala Ala Arg Ile Arg Lys Arg Lys Glu 
625                 630                 635                 640 


Glu Lys Leu Lys Glu Gln Glu Gln Lys Met Lys Glu Lys Gln Glu Lys 
                645                 650                 655     


Leu Lys Glu Asp Glu Gln Arg Asn Ser Thr Ala Asp Ile Ser Ile Gly 
            660                 665                 670         


Glu Glu Glu Arg Glu Asp Phe Asp Thr Ser Ile Glu Ser Lys Asp Thr 
        675                 680                 685             


Glu Gln Lys Glu Leu Asp Gln Asp Met Val Thr Glu Asp Glu Asp Asp 
    690                 695                 700                 


Pro Gly Ser His Lys Arg Gly Arg Arg Gly Lys Arg Gly Gln Asn Gly 
705                 710                 715                 720 


Phe Lys Glu Phe Thr Arg Gln Glu Gln Ile Asn Cys Val Thr Arg Glu 
                725                 730                 735     


Pro Leu Thr Ala Asp Glu Glu Glu Ala Leu Lys Gln Glu His Gln Arg 
            740                 745                 750         


Lys Glu Lys Glu Leu Leu Glu Lys Ile Gln Ser Ala Ile Ala Cys Thr 
        755                 760                 765             


Asn Ile Phe Pro Leu Gly Arg Asp Arg Met Tyr Arg Arg Tyr Trp Ile 
    770                 775                 780                 


Phe Pro Ser Ile Pro Gly Leu Phe Ile Glu Glu Asp Tyr Ser Gly Leu 
785                 790                 795                 800 


Thr Glu Asp Met Leu Leu Pro Arg Pro Ser Ser Phe Gln Asn Asn Val 
                805                 810                 815     


Gln Ser Gln Asp Pro Gln Val Ser Thr Lys Thr Gly Glu Pro Leu Met 
            820                 825                 830         


Ser Glu Ser Thr Ser Asn Ile Asp Gln Gly Pro Arg Asp His Ser Val 
        835                 840                 845             


Gln Leu Pro Lys Pro Val His Lys Pro Asn Arg Trp Cys Phe Tyr Ser 
    850                 855                 860                 


Ser Cys Glu Gln Leu Asp Gln Leu Ile Glu Ala Leu Asn Ser Arg Gly 
865                 870                 875                 880 


His Arg Glu Ser Ala Leu Lys Glu Thr Leu Leu Gln Glu Lys Ser Arg 
                885                 890                 895     


Ile Cys Ala Gln Leu Ala Arg Phe Ser Glu Glu Lys Phe His Phe Ser 
            900                 905                 910         


Asp Lys Pro Gln Pro Asp Ser Lys Pro Thr Tyr Ser Arg Gly Arg Ser 
        915                 920                 925             


Ser Asn Ala Tyr Asp Pro Ser Gln Met Cys Ala Glu Lys Gln Leu Glu 
    930                 935                 940                 


Leu Arg Leu Arg Asp Phe Leu Leu Asp Ile Glu Asp Arg Ile Tyr Gln 
945                 950                 955                 960 


Gly Thr Leu Gly Ala Ile Lys Val Thr Asp Arg His Ile Trp Arg Ser 
                965                 970                 975     


Ala Leu Glu Ser Gly Arg Tyr Glu Leu Leu Ser Glu Glu Asn Lys Glu 
            980                 985                 990         


Asn Gly Ile Ile Lys Thr Val Asn  Glu Asp Val Glu Glu  Met Glu Ile 
        995                 1000                 1005             


Asp Glu  Gln Thr Lys Val Ile  Val Lys Asp Arg Leu  Leu Gly Ile 
    1010                 1015                 1020             


Lys Thr  Glu Thr Pro Ser Thr  Val Ser Thr Asn Ala  Ser Thr Pro 
    1025                 1030                 1035             


Gln Ser  Val Ser Ser Val Val  His Tyr Leu Ala Met  Ala Leu Phe 
    1040                 1045                 1050             


Gln Ile  Glu Gln Gly Ile Glu  Arg Arg Phe Leu Lys  Ala Pro Leu 
    1055                 1060                 1065             


Asp Ala  Ser Asp Ser Gly Arg  Ser Tyr Lys Thr Val  Leu Asp Arg 
    1070                 1075                 1080             


Trp Arg  Glu Ser Leu Leu Ser  Ser Ala Ser Leu Ser  Gln Val Phe 
    1085                 1090                 1095             


Leu His  Leu Ser Thr Leu Asp  Arg Ser Val Ile Trp  Ser Lys Ser 
    1100                 1105                 1110             


Ile Leu  Asn Ala Arg Cys Lys  Ile Cys Arg Lys Lys  Gly Asp Ala 
    1115                 1120                 1125             


Glu Asn  Met Val Leu Cys Asp  Gly Cys Asp Arg Gly  His His Thr 
    1130                 1135                 1140             


Tyr Cys  Val Arg Pro Lys Leu  Lys Thr Val Pro Glu  Gly Asp Trp 
    1145                 1150                 1155             


Phe Cys  Pro Glu Cys Arg Pro  Lys Gln Arg Ser Arg  Arg Leu Ser 
    1160                 1165                 1170             


Ser Arg  Gln Arg Pro Ser Leu  Glu Ser Asp Glu Asp  Val Glu Asp 
    1175                 1180                 1185             


Ser Met  Gly Gly Glu Asp Asp  Glu Val Asp Gly Asp  Glu Glu Glu 
    1190                 1195                 1200             


Gly Gln  Ser Glu Glu Glu Glu  Tyr Glu Val Glu Gln  Asp Glu Asp 
    1205                 1210                 1215             


Asp Ser  Gln Glu Glu Glu Glu  Val Ser Leu Pro Lys  Arg Gly Arg 
    1220                 1225                 1230             


Pro Gln  Val Arg Leu Pro Val  Lys Thr Arg Gly Lys  Leu Ser Ser 
    1235                 1240                 1245             


Ser Phe  Ser Ser Arg Gly Gln  Gln Gln Glu Pro Gly  Arg Tyr Pro 
    1250                 1255                 1260             


Ser Arg  Ser Gln Gln Ser Thr  Pro Lys Thr Thr Val  Ser Ser Lys 
    1265                 1270                 1275             


Thr Gly  Arg Ser Leu Arg Lys  Ile Asn Ser Ala Pro  Pro Thr Glu 
    1280                 1285                 1290             


Thr Lys  Ser Leu Arg Ile Ala  Ser Arg Ser Thr Arg  His Ser His 
    1295                 1300                 1305             


Gly Pro  Leu Gln Ala Asp Val  Phe Val Glu Leu Leu  Ser Pro Arg 
    1310                 1315                 1320             


Arg Lys  Arg Arg Gly Arg Lys  Ser Ala Asn Asn Thr  Pro Glu Asn 
    1325                 1330                 1335             


Ser Pro  Asn Phe Pro Asn Phe  Arg Val Ile Ala Thr  Lys Ser Ser 
    1340                 1345                 1350             


Glu Gln  Ser Arg Ser Val Asn  Ile Ala Ser Lys Leu  Ser Leu Gln 
    1355                 1360                 1365             


Glu Ser  Glu Ser Lys Arg Arg  Cys Arg Lys Arg Gln  Ser Pro Glu 
    1370                 1375                 1380             


Pro Ser  Pro Val Thr Leu Gly  Arg Arg Ser Ser Gly  Arg Gln Gly 
    1385                 1390                 1395             


Gly Val  His Glu Leu Ser Ala  Phe Glu Gln Leu Val  Val Glu Leu 
    1400                 1405                 1410             


Val Arg  His Asp Asp Ser Trp  Pro Phe Leu Lys Leu  Val Ser Lys 
    1415                 1420                 1425             


Ile Gln  Val Pro Asp Tyr Tyr  Asp Ile Ile Lys Lys  Pro Ile Ala 
    1430                 1435                 1440             


Leu Asn  Ile Ile Arg Glu Lys  Val Asn Lys Cys Glu  Tyr Lys Leu 
    1445                 1450                 1455             


Ala Ser  Glu Phe Ile Asp Asp  Ile Glu Leu Met Phe  Ser Asn Cys 
    1460                 1465                 1470             


Phe Glu  Tyr Asn Pro Arg Asn  Thr Ser Glu Ala Lys  Ala Gly Thr 
    1475                 1480                 1485             


Arg Leu  Gln Ala Phe Phe His  Ile Gln Ala Gln Lys  Leu Gly Leu 
    1490                 1495                 1500             


His Val  Thr Pro Ser Asn Val  Asp Gln Val Ser Thr  Pro Pro Ala 
    1505                 1510                 1515             


Ala Lys  Lys Ser Arg Ile 
    1520                 


<210>  4163
<211>  280
<212>  PRT
<213>  homo sapiens

<400>  4163

Met Pro Ala Asp Ile Met Glu Lys Asn Ser Ser Ser Pro Val Ala Ala 
1               5                   10                  15      


Thr Pro Ala Ser Val Asn Thr Thr Pro Asp Lys Pro Lys Thr Ala Ser 
            20                  25                  30          


Glu His Arg Lys Ser Ser Lys Pro Ile Met Glu Lys Arg Arg Arg Ala 
        35                  40                  45              


Arg Ile Asn Glu Ser Leu Ser Gln Leu Lys Thr Leu Ile Leu Asp Ala 
    50                  55                  60                  


Leu Lys Lys Asp Ser Ser Arg His Ser Lys Leu Glu Lys Ala Asp Ile 
65                  70                  75                  80  


Leu Glu Met Thr Val Lys His Leu Arg Asn Leu Gln Arg Ala Gln Met 
                85                  90                  95      


Thr Ala Ala Leu Ser Thr Asp Pro Ser Val Leu Gly Lys Tyr Arg Ala 
            100                 105                 110         


Gly Phe Ser Glu Cys Met Asn Glu Val Thr Arg Phe Leu Ser Thr Cys 
        115                 120                 125             


Glu Gly Val Asn Thr Glu Val Arg Thr Arg Leu Leu Gly His Leu Ala 
    130                 135                 140                 


Asn Cys Met Thr Gln Ile Asn Ala Met Thr Tyr Pro Gly Gln Pro His 
145                 150                 155                 160 


Pro Ala Leu Gln Ala Pro Pro Pro Pro Pro Pro Gly Pro Gly Gly Pro 
                165                 170                 175     


Gln His Ala Pro Phe Ala Pro Pro Pro Pro Leu Val Pro Ile Pro Gly 
            180                 185                 190         


Gly Ala Ala Pro Pro Pro Gly Gly Ala Pro Cys Lys Leu Gly Ser Gln 
        195                 200                 205             


Ala Gly Glu Ala Ala Lys Val Phe Gly Gly Phe Gln Val Val Pro Ala 
    210                 215                 220                 


Pro Asp Gly Gln Phe Ala Phe Leu Ile Pro Asn Gly Ala Phe Ala His 
225                 230                 235                 240 


Ser Gly Pro Val Ile Pro Val Tyr Thr Ser Asn Ser Gly Thr Ser Val 
                245                 250                 255     


Gly Pro Asn Ala Val Ser Pro Ser Ser Gly Pro Ser Leu Thr Ala Asp 
            260                 265                 270         


Ser Met Trp Arg Pro Trp Arg Asn 
        275                 280 


<210>  4164
<211>  221
<212>  PRT
<213>  homo sapiens

<400>  4164

Met Ala Ala Asp Thr Pro Gly Lys Pro Ser Ala Ser Pro Met Ala Gly 
1               5                   10                  15      


Ala Pro Ala Ser Ala Ser Arg Thr Pro Asp Lys Pro Arg Ser Ala Ala 
            20                  25                  30          


Glu His Arg Lys Ser Ser Lys Pro Val Met Glu Lys Arg Arg Arg Ala 
        35                  40                  45              


Arg Ile Asn Glu Ser Leu Ala Gln Leu Lys Thr Leu Ile Leu Asp Ala 
    50                  55                  60                  


Leu Arg Lys Glu Ser Ser Arg His Ser Lys Leu Glu Lys Ala Asp Ile 
65                  70                  75                  80  


Leu Glu Met Thr Val Arg His Leu Arg Ser Leu Arg Arg Val Gln Val 
                85                  90                  95      


Thr Ala Ala Leu Ser Ala Asp Pro Ala Val Leu Gly Lys Tyr Arg Ala 
            100                 105                 110         


Gly Phe His Glu Cys Leu Ala Glu Val Asn Arg Phe Leu Ala Gly Cys 
        115                 120                 125             


Glu Gly Val Pro Ala Asp Val Arg Ser Arg Leu Leu Gly His Leu Ala 
    130                 135                 140                 


Ala Cys Leu Arg Gln Leu Gly Pro Ser Arg Arg Pro Ala Ser Leu Ser 
145                 150                 155                 160 


Pro Ala Ala Pro Ala Glu Ala Pro Ala Pro Glu Val Tyr Ala Gly Arg 
                165                 170                 175     


Pro Leu Leu Pro Ser Leu Gly Gly Pro Phe Pro Leu Leu Ala Pro Pro 
            180                 185                 190         


Leu Leu Pro Gly Leu Thr Arg Ala Leu Pro Ala Ala Pro Arg Ala Gly 
        195                 200                 205             


Pro Gln Gly Pro Gly Gly Pro Trp Arg Pro Trp Leu Arg 
    210                 215                 220     


<210>  4165
<211>  247
<212>  PRT
<213>  homo sapiens

<400>  4165

Met Ala Ala Asp Thr Pro Gly Lys Pro Ser Ala Ser Pro Met Ala Gly 
1               5                   10                  15      


Ala Pro Ala Ser Ala Ser Arg Thr Pro Asp Lys Pro Arg Ser Ala Ala 
            20                  25                  30          


Glu His Arg Lys Val Gly Ser Arg Pro Gly Val Arg Gly Ala Thr Gly 
        35                  40                  45              


Gly Arg Glu Gly Arg Gly Thr Gln Pro Val Pro Asp Pro Gln Ser Ser 
    50                  55                  60                  


Lys Pro Val Met Glu Lys Arg Arg Arg Ala Arg Ile Asn Glu Ser Leu 
65                  70                  75                  80  


Ala Gln Leu Lys Thr Leu Ile Leu Asp Ala Leu Arg Lys Glu Ser Ser 
                85                  90                  95      


Arg His Ser Lys Leu Glu Lys Ala Asp Ile Leu Glu Met Thr Val Arg 
            100                 105                 110         


His Leu Arg Ser Leu Arg Arg Val Gln Val Thr Ala Ala Leu Ser Ala 
        115                 120                 125             


Asp Pro Ala Val Leu Gly Lys Tyr Arg Ala Gly Phe His Glu Cys Leu 
    130                 135                 140                 


Ala Glu Val Asn Arg Phe Leu Ala Gly Cys Glu Gly Val Pro Ala Asp 
145                 150                 155                 160 


Val Arg Ser Arg Leu Leu Gly His Leu Ala Ala Cys Leu Arg Gln Leu 
                165                 170                 175     


Gly Pro Ser Arg Arg Pro Ala Ser Leu Ser Pro Ala Ala Pro Ala Glu 
            180                 185                 190         


Ala Pro Ala Pro Glu Val Tyr Ala Gly Arg Pro Leu Leu Pro Ser Leu 
        195                 200                 205             


Gly Gly Pro Phe Pro Leu Leu Ala Pro Pro Leu Leu Pro Gly Leu Thr 
    210                 215                 220                 


Arg Ala Leu Pro Ala Ala Pro Arg Ala Gly Pro Gln Gly Pro Gly Gly 
225                 230                 235                 240 


Pro Trp Arg Pro Trp Leu Arg 
                245         


<210>  4166
<211>  166
<212>  PRT
<213>  homo sapiens

<400>  4166

Met Ala Pro Ser Thr Val Ala Val Glu Leu Leu Ser Pro Lys Glu Lys 
1               5                   10                  15      


Asn Arg Leu Arg Lys Pro Val Val Glu Lys Met Arg Arg Asp Arg Ile 
            20                  25                  30          


Asn Ser Ser Ile Glu Gln Leu Lys Leu Leu Leu Glu Gln Glu Phe Ala 
        35                  40                  45              


Arg His Gln Pro Asn Ser Lys Leu Glu Lys Ala Asp Ile Leu Glu Met 
    50                  55                  60                  


Ala Val Ser Tyr Leu Lys His Ser Lys Ala Phe Val Ala Ala Ala Gly 
65                  70                  75                  80  


Pro Lys Ser Leu His Gln Asp Tyr Ser Glu Gly Tyr Ser Trp Cys Leu 
                85                  90                  95      


Gln Glu Ala Val Gln Phe Leu Thr Leu His Ala Ala Ser Asp Thr Gln 
            100                 105                 110         


Met Lys Leu Leu Tyr His Phe Gln Arg Pro Pro Ala Ala Pro Ala Ala 
        115                 120                 125             


Pro Ala Lys Glu Pro Lys Ala Pro Gly Ala Ala Pro Pro Pro Ala Leu 
    130                 135                 140                 


Ser Ala Lys Ala Thr Ala Ala Ala Ala Ala Ala His Gln Pro Ala Cys 
145                 150                 155                 160 


Gly Leu Trp Arg Pro Trp 
                165     


<210>  4167
<211>  308
<212>  PRT
<213>  homo sapiens

<400>  4167

Met Lys Arg Ala His Pro Glu Tyr Ser Ser Ser Asp Ser Glu Leu Asp 
1               5                   10                  15      


Glu Thr Ile Glu Val Glu Lys Glu Ser Ala Asp Glu Asn Gly Asn Leu 
            20                  25                  30          


Ser Ser Ala Leu Gly Ser Met Ser Pro Thr Thr Ser Ser Gln Ile Leu 
        35                  40                  45              


Ala Arg Lys Arg Arg Arg Gly Ile Ile Glu Lys Arg Arg Arg Asp Arg 
    50                  55                  60                  


Ile Asn Asn Ser Leu Ser Glu Leu Arg Arg Leu Val Pro Ser Ala Phe 
65                  70                  75                  80  


Glu Lys Gln Val Met Glu Gln Gly Ser Ala Lys Leu Glu Lys Ala Glu 
                85                  90                  95      


Ile Leu Gln Met Thr Val Asp His Leu Lys Met Leu His Thr Ala Gly 
            100                 105                 110         


Gly Lys Gly Tyr Phe Asp Ala His Ala Leu Ala Met Asp Tyr Arg Ser 
        115                 120                 125             


Leu Gly Phe Arg Glu Cys Leu Ala Glu Val Ala Arg Tyr Leu Ser Ile 
    130                 135                 140                 


Ile Glu Gly Leu Asp Ala Ser Asp Pro Leu Arg Val Arg Leu Val Ser 
145                 150                 155                 160 


His Leu Asn Asn Tyr Ala Ser Gln Arg Glu Ala Ala Ser Gly Ala His 
                165                 170                 175     


Ala Gly Leu Gly His Ile Pro Trp Gly Thr Val Phe Gly His His Pro 
            180                 185                 190         


His Ile Ala His Pro Leu Leu Leu Pro Gln Asn Gly His Gly Asn Ala 
        195                 200                 205             


Gly Thr Thr Ala Ser Pro Thr Glu Pro His His Gln Gly Arg Leu Gly 
    210                 215                 220                 


Ser Ala His Pro Glu Ala Pro Ala Leu Arg Ala Pro Pro Ser Gly Ser 
225                 230                 235                 240 


Leu Gly Pro Val Leu Pro Val Val Thr Ser Ala Ser Lys Leu Ser Pro 
                245                 250                 255     


Pro Leu Leu Ser Ser Val Ala Ser Leu Ser Ala Phe Pro Phe Ser Phe 
            260                 265                 270         


Gly Ser Phe His Leu Leu Ser Pro Asn Ala Leu Ser Pro Ser Ala Pro 
        275                 280                 285             


Thr Gln Ala Ala Asn Leu Gly Lys Pro Tyr Arg Pro Trp Gly Thr Glu 
    290                 295                 300                 


Ile Gly Ala Phe 
305             


<210>  4168
<211>  304
<212>  PRT
<213>  homo sapiens

<400>  4168

Met Lys Arg Ala His Pro Glu Tyr Ser Ser Ser Asp Ser Glu Leu Asp 
1               5                   10                  15      


Glu Thr Ile Glu Val Glu Lys Glu Ser Ala Asp Glu Asn Gly Asn Leu 
            20                  25                  30          


Ser Ser Ala Leu Gly Ser Met Ser Pro Thr Thr Ser Ser Gln Ile Leu 
        35                  40                  45              


Ala Arg Lys Arg Arg Arg Gly Ile Ile Glu Lys Arg Arg Arg Asp Arg 
    50                  55                  60                  


Ile Asn Asn Ser Leu Ser Glu Leu Arg Arg Leu Val Pro Ser Ala Phe 
65                  70                  75                  80  


Glu Lys Gln Gly Ser Ala Lys Leu Glu Lys Ala Glu Ile Leu Gln Met 
                85                  90                  95      


Thr Val Asp His Leu Lys Met Leu His Thr Ala Gly Gly Lys Gly Tyr 
            100                 105                 110         


Phe Asp Ala His Ala Leu Ala Met Asp Tyr Arg Ser Leu Gly Phe Arg 
        115                 120                 125             


Glu Cys Leu Ala Glu Val Ala Arg Tyr Leu Ser Ile Ile Glu Gly Leu 
    130                 135                 140                 


Asp Ala Ser Asp Pro Leu Arg Val Arg Leu Val Ser His Leu Asn Asn 
145                 150                 155                 160 


Tyr Ala Ser Gln Arg Glu Ala Ala Ser Gly Ala His Ala Gly Leu Gly 
                165                 170                 175     


His Ile Pro Trp Gly Thr Val Phe Gly His His Pro His Ile Ala His 
            180                 185                 190         


Pro Leu Leu Leu Pro Gln Asn Gly His Gly Asn Ala Gly Thr Thr Ala 
        195                 200                 205             


Ser Pro Thr Glu Pro His His Gln Gly Arg Leu Gly Ser Ala His Pro 
    210                 215                 220                 


Glu Ala Pro Ala Leu Arg Ala Pro Pro Ser Gly Ser Leu Gly Pro Val 
225                 230                 235                 240 


Leu Pro Val Val Thr Ser Ala Ser Lys Leu Ser Pro Pro Leu Leu Ser 
                245                 250                 255     


Ser Val Ala Ser Leu Ser Ala Phe Pro Phe Ser Phe Gly Ser Phe His 
            260                 265                 270         


Leu Leu Ser Pro Asn Ala Leu Ser Pro Ser Ala Pro Thr Gln Ala Ala 
        275                 280                 285             


Asn Leu Gly Lys Pro Tyr Arg Pro Trp Gly Thr Glu Ile Gly Ala Phe 
    290                 295                 300                 


<210>  4169
<211>  506
<212>  PRT
<213>  homo sapiens

<400>  4169

Met Ser Val Glu Pro Pro Pro Glu Leu Glu Glu Lys Ala Ala Ser Glu 
1               5                   10                  15      


Pro Glu Ala Gly Ala Met Pro Glu Lys Arg Ala Gly Ala Gln Ala Ala 
            20                  25                  30          


Gly Ser Thr Trp Leu Gln Gly Phe Gly Arg Pro Ser Val Tyr His Ala 
        35                  40                  45              


Ala Ile Val Ile Phe Leu Glu Phe Phe Ala Trp Gly Leu Leu Thr Thr 
    50                  55                  60                  


Pro Met Leu Thr Val Leu His Glu Thr Phe Ser Gln His Thr Phe Leu 
65                  70                  75                  80  


Met Asn Gly Leu Ile Gln Gly Val Lys Gly Leu Leu Ser Phe Leu Ser 
                85                  90                  95      


Ala Pro Leu Ile Gly Ala Leu Ser Asp Val Trp Gly Arg Lys Pro Phe 
            100                 105                 110         


Leu Leu Gly Thr Val Phe Phe Thr Cys Phe Pro Ile Pro Leu Met Arg 
        115                 120                 125             


Ile Ser Pro Trp Trp Tyr Phe Ala Met Ile Ser Val Ser Gly Val Phe 
    130                 135                 140                 


Ser Val Thr Phe Ser Val Ile Phe Ala Tyr Val Ala Asp Val Thr Gln 
145                 150                 155                 160 


Glu His Glu Arg Ser Thr Ala Tyr Gly Trp Val Ser Ala Thr Phe Ala 
                165                 170                 175     


Ala Ser Leu Val Ser Ser Pro Ala Ile Gly Ala Tyr Leu Ser Ala Ser 
            180                 185                 190         


Tyr Gly Asp Ser Leu Val Val Leu Val Ala Thr Val Val Ala Leu Leu 
        195                 200                 205             


Asp Ile Cys Phe Ile Leu Val Ala Val Pro Glu Ser Leu Pro Glu Lys 
    210                 215                 220                 


Met Arg Pro Val Ser Trp Gly Ala Gln Ile Ser Trp Lys Gln Ala Asp 
225                 230                 235                 240 


Pro Phe Ala Ser Leu Lys Lys Val Gly Lys Asp Ser Thr Val Leu Leu 
                245                 250                 255     


Ile Cys Ile Thr Val Phe Leu Ser Tyr Leu Pro Glu Ala Gly Gln Tyr 
            260                 265                 270         


Ser Ser Phe Phe Leu Tyr Leu Arg Gln Val Ile Gly Phe Gly Ser Val 
        275                 280                 285             


Lys Ile Ala Ala Phe Ile Ala Met Val Gly Ile Leu Ser Ile Val Ala 
    290                 295                 300                 


Gln Thr Ala Phe Leu Ser Ile Leu Met Arg Ser Leu Gly Asn Lys Asn 
305                 310                 315                 320 


Thr Val Leu Leu Gly Leu Gly Phe Gln Met Leu Gln Leu Ala Trp Tyr 
                325                 330                 335     


Gly Phe Gly Ser Gln Ala Trp Met Met Trp Ala Ala Gly Thr Val Ala 
            340                 345                 350         


Ala Met Ser Ser Ile Thr Phe Pro Ala Ile Ser Ala Leu Val Ser Arg 
        355                 360                 365             


Asn Ala Glu Ser Asp Gln Gln Gly Val Ala Gln Gly Ile Ile Thr Gly 
    370                 375                 380                 


Ile Arg Gly Leu Cys Asn Gly Leu Gly Pro Ala Leu Tyr Gly Phe Ile 
385                 390                 395                 400 


Phe Tyr Met Phe His Val Glu Leu Thr Glu Leu Gly Pro Lys Leu Asn 
                405                 410                 415     


Ser Asn Asn Val Pro Leu Gln Gly Ala Val Ile Pro Gly Pro Pro Phe 
            420                 425                 430         


Leu Phe Gly Ala Cys Ile Val Leu Met Ser Phe Leu Val Ala Leu Phe 
        435                 440                 445             


Ile Pro Glu Tyr Ser Lys Ala Ser Gly Val Gln Lys His Ser Asn Ser 
    450                 455                 460                 


Ser Ser Gly Ser Leu Thr Asn Thr Pro Glu Arg Gly Ser Asp Glu Asp 
465                 470                 475                 480 


Ile Glu Pro Leu Leu Gln Asp Ser Ser Ile Trp Glu Leu Ser Ser Phe 
                485                 490                 495     


Glu Glu Pro Gly Asn Gln Cys Thr Glu Leu 
            500                 505     


<210>  4170
<211>  161
<212>  PRT
<213>  homo sapiens

<400>  4170

Met Ser Val Pro Gly Pro Tyr Gln Ala Ala Thr Gly Pro Ser Ser Ala 
1               5                   10                  15      


Pro Ser Ala Pro Pro Ser Tyr Glu Glu Thr Val Ala Val Asn Ser Tyr 
            20                  25                  30          


Tyr Pro Thr Pro Pro Ala Pro Met Pro Gly Pro Thr Thr Gly Leu Val 
        35                  40                  45              


Thr Gly Pro Asp Gly Lys Gly Met Asn Pro Pro Ser Tyr Tyr Thr Gln 
    50                  55                  60                  


Pro Ala Pro Ile Pro Asn Asn Asn Pro Ile Thr Val Gln Thr Val Tyr 
65                  70                  75                  80  


Val Gln His Pro Ile Thr Phe Leu Asp Arg Pro Ile Gln Met Cys Cys 
                85                  90                  95      


Pro Ser Cys Asn Lys Met Ile Val Ser Gln Leu Ser Tyr Asn Ala Gly 
            100                 105                 110         


Ala Leu Thr Trp Leu Ser Cys Gly Ser Leu Cys Leu Leu Gly Cys Ile 
        115                 120                 125             


Ala Gly Cys Cys Phe Ile Pro Phe Cys Val Asp Ala Leu Gln Asp Val 
    130                 135                 140                 


Asp His Tyr Cys Pro Asn Cys Arg Ala Leu Leu Gly Thr Tyr Lys Arg 
145                 150                 155                 160 


Leu 
    


<210>  4171
<211>  457
<212>  PRT
<213>  homo sapiens

<400>  4171

Met Thr Thr Asp Glu Gly Ala Lys Asn Asn Glu Glu Ser Pro Thr Ala 
1               5                   10                  15      


Thr Val Ala Glu Gln Gly Glu Asp Ile Thr Ser Lys Lys Asp Arg Gly 
            20                  25                  30          


Val Leu Lys Ile Val Lys Arg Val Gly Asn Gly Glu Glu Thr Pro Met 
        35                  40                  45              


Ile Gly Asp Lys Val Tyr Val His Tyr Lys Gly Lys Leu Ser Asn Gly 
    50                  55                  60                  


Lys Lys Phe Asp Ser Ser His Asp Arg Asn Glu Pro Phe Val Phe Ser 
65                  70                  75                  80  


Leu Gly Lys Gly Gln Val Ile Lys Ala Trp Asp Ile Gly Val Ala Thr 
                85                  90                  95      


Met Lys Lys Gly Glu Ile Cys His Leu Leu Cys Lys Pro Glu Tyr Ala 
            100                 105                 110         


Tyr Gly Ser Ala Gly Ser Leu Pro Lys Ile Pro Ser Asn Ala Thr Leu 
        115                 120                 125             


Phe Phe Glu Ile Glu Leu Leu Asp Phe Lys Gly Glu Asp Leu Phe Glu 
    130                 135                 140                 


Asp Gly Gly Ile Ile Arg Arg Thr Lys Arg Lys Gly Glu Gly Tyr Ser 
145                 150                 155                 160 


Asn Pro Asn Glu Gly Ala Thr Val Glu Ile His Leu Glu Gly Arg Cys 
                165                 170                 175     


Gly Gly Arg Met Phe Asp Cys Arg Asp Val Ala Phe Thr Val Gly Glu 
            180                 185                 190         


Gly Glu Asp His Asp Ile Pro Ile Gly Ile Asp Lys Ala Leu Glu Lys 
        195                 200                 205             


Met Gln Arg Glu Glu Gln Cys Ile Leu Tyr Leu Gly Pro Arg Tyr Gly 
    210                 215                 220                 


Phe Gly Glu Ala Gly Lys Pro Lys Phe Gly Ile Glu Pro Asn Ala Glu 
225                 230                 235                 240 


Leu Ile Tyr Glu Val Thr Leu Lys Ser Phe Glu Lys Ala Lys Glu Ser 
                245                 250                 255     


Trp Glu Met Asp Thr Lys Glu Lys Leu Glu Gln Ala Ala Ile Val Lys 
            260                 265                 270         


Glu Lys Gly Thr Val Tyr Phe Lys Gly Gly Lys Tyr Met Gln Ala Val 
        275                 280                 285             


Ile Gln Tyr Gly Lys Ile Val Ser Trp Leu Glu Met Glu Tyr Gly Leu 
    290                 295                 300                 


Ser Glu Lys Glu Ser Lys Ala Ser Glu Ser Phe Leu Leu Ala Ala Phe 
305                 310                 315                 320 


Leu Asn Leu Ala Met Cys Tyr Leu Lys Leu Arg Glu Tyr Thr Lys Ala 
                325                 330                 335     


Val Glu Cys Cys Asp Lys Ala Leu Gly Leu Asp Ser Ala Asn Glu Lys 
            340                 345                 350         


Gly Leu Tyr Arg Arg Gly Glu Ala Gln Leu Leu Met Asn Glu Phe Glu 
        355                 360                 365             


Ser Ala Lys Gly Asp Phe Glu Lys Val Leu Glu Val Asn Pro Gln Asn 
    370                 375                 380                 


Lys Ala Ala Arg Leu Gln Ile Ser Met Cys Gln Lys Lys Ala Lys Glu 
385                 390                 395                 400 


His Asn Glu Arg Asp Arg Arg Ile Tyr Ala Asn Met Phe Lys Lys Phe 
                405                 410                 415     


Ala Glu Gln Asp Ala Lys Glu Glu Ala Asn Lys Ala Met Gly Lys Lys 
            420                 425                 430         


Thr Ser Glu Gly Val Thr Asn Glu Lys Gly Thr Asp Ser Gln Ala Met 
        435                 440                 445             


Glu Glu Glu Lys Pro Glu Gly His Val 
    450                 455         


<210>  4172
<211>  158
<212>  PRT
<213>  homo sapiens

<400>  4172

Met Ser Ser Ala Ile Glu Arg Lys Ser Leu Asp Pro Ser Glu Glu Pro 
1               5                   10                  15      


Val Asp Glu Val Leu Gln Ile Pro Pro Ser Leu Leu Thr Cys Gly Gly 
            20                  25                  30          


Cys Gln Gln Asn Ile Gly Asp Arg Tyr Phe Leu Lys Ala Ile Asp Gln 
        35                  40                  45              


Tyr Trp His Glu Asp Cys Leu Ser Cys Asp Leu Cys Gly Cys Arg Leu 
    50                  55                  60                  


Gly Glu Val Gly Arg Arg Leu Tyr Tyr Lys Leu Gly Arg Lys Leu Cys 
65                  70                  75                  80  


Arg Arg Asp Tyr Leu Arg Leu Phe Gly Gln Asp Gly Leu Cys Ala Ser 
                85                  90                  95      


Cys Asp Lys Arg Ile Arg Ala Tyr Glu Met Thr Met Arg Val Lys Asp 
            100                 105                 110         


Lys Val Tyr His Leu Glu Cys Phe Lys Cys Ala Ala Cys Gln Lys His 
        115                 120                 125             


Phe Cys Val Gly Asp Arg Tyr Leu Leu Ile Asn Ser Asp Ile Val Cys 
    130                 135                 140                 


Glu Gln Asp Ile Tyr Glu Trp Thr Lys Ile Asn Gly Met Ile 
145                 150                 155             


<210>  4173
<211>  1268
<212>  PRT
<213>  homo sapiens

<400>  4173

Met Ser Ala Pro Ala Gly Ser Ser His Pro Ala Ala Ser Ala Arg Ile 
1               5                   10                  15      


Pro Pro Lys Phe Gly Gly Ala Ala Val Ser Gly Ala Ala Ala Pro Ala 
            20                  25                  30          


Gly Pro Gly Ala Gly Pro Ala Pro His Gln Gln Asn Gly Pro Ala Gln 
        35                  40                  45              


Asn Gln Met Gln Val Pro Ser Gly Tyr Gly Leu His His Gln Asn Tyr 
    50                  55                  60                  


Ile Ala Pro Ser Gly His Tyr Ser Gln Gly Pro Gly Lys Met Thr Ser 
65                  70                  75                  80  


Leu Pro Leu Asp Thr Gln Cys Gly Asp Tyr Tyr Ser Ala Leu Tyr Thr 
                85                  90                  95      


Val Pro Thr Gln Asn Val Thr Pro Asn Thr Val Asn Gln Gln Pro Gly 
            100                 105                 110         


Ala Gln Gln Leu Tyr Ser Arg Gly Pro Pro Ala Pro His Ile Val Gly 
        115                 120                 125             


Ser Thr Leu Gly Ser Phe Gln Gly Ala Ala Ser Ser Ala Ser His Leu 
    130                 135                 140                 


His Thr Ser Ala Ser Gln Pro Tyr Ser Ser Phe Val Asn His Tyr Asn 
145                 150                 155                 160 


Ser Pro Ala Met Tyr Ser Ala Ser Ser Ser Val Ala Ser Gln Gly Phe 
                165                 170                 175     


Pro Ser Thr Cys Gly His Tyr Ala Met Ser Thr Val Ser Asn Ala Ala 
            180                 185                 190         


Tyr Pro Ser Val Ser Tyr Pro Ser Leu Pro Ala Gly Asp Thr Tyr Gly 
        195                 200                 205             


Gln Met Phe Thr Ser Gln Asn Ala Pro Thr Val Arg Pro Val Lys Asp 
    210                 215                 220                 


Asn Ser Phe Ser Gly Gln Asn Thr Ala Ile Ser His Pro Ser Pro Leu 
225                 230                 235                 240 


Pro Pro Leu Pro Ser Gln Gln His His Gln Gln Gln Ser Leu Ser Gly 
                245                 250                 255     


Tyr Ser Thr Leu Thr Trp Ser Ser Pro Gly Leu Pro Ser Thr Gln Asp 
            260                 265                 270         


Asn Leu Ile Arg Asn His Thr Gly Ser Leu Ala Val Ala Asn Asn Asn 
        275                 280                 285             


Pro Thr Ile Thr Val Ala Asp Ser Leu Ser Cys Pro Val Met Gln Asn 
    290                 295                 300                 


Val Gln Pro Pro Lys Ser Ser Pro Val Val Ser Thr Val Leu Ser Gly 
305                 310                 315                 320 


Ser Ser Gly Ser Ser Ser Thr Arg Thr Pro Pro Thr Ala Asn His Pro 
                325                 330                 335     


Val Glu Pro Val Thr Ser Val Thr Gln Pro Ser Glu Leu Leu Gln Gln 
            340                 345                 350         


Lys Gly Val Gln Tyr Gly Glu Tyr Val Asn Asn Gln Ala Ser Ser Ala 
        355                 360                 365             


Pro Thr Pro Leu Ser Ser Thr Ser Asp Asp Glu Glu Glu Glu Glu Glu 
    370                 375                 380                 


Asp Glu Glu Ala Gly Val Asp Ser Ser Ser Thr Thr Ser Ser Ala Ser 
385                 390                 395                 400 


Pro Met Pro Asn Ser Tyr Asp Ala Leu Glu Gly Gly Ser Tyr Pro Asp 
                405                 410                 415     


Met Leu Ser Ser Ser Ala Ser Ser Pro Ala Pro Asp Pro Ala Pro Glu 
            420                 425                 430         


Pro Asp Pro Ala Ser Ala Pro Ala Pro Ala Ser Ala Pro Ala Pro Val 
        435                 440                 445             


Val Pro Gln Pro Ser Lys Met Ala Lys Pro Phe Gly Tyr Gly Tyr Pro 
    450                 455                 460                 


Thr Leu Gln Pro Gly Tyr Gln Asn Ala Thr Ala Pro Leu Ile Ser Gly 
465                 470                 475                 480 


Val Gln Pro Ser Asn Pro Val Tyr Ser Gly Phe Gln Gln Tyr Pro Gln 
                485                 490                 495     


Gln Tyr Pro Gly Val Asn Gln Leu Ser Ser Ser Ile Gly Gly Leu Ser 
            500                 505                 510         


Leu Gln Ser Ser Pro Gln Pro Glu Ser Leu Arg Pro Val Asn Leu Thr 
        515                 520                 525             


Gln Glu Arg Asn Ile Leu Pro Met Thr Pro Val Trp Ala Pro Val Pro 
    530                 535                 540                 


Asn Leu Asn Ala Asp Leu Lys Lys Leu Asn Cys Ser Pro Asp Ser Phe 
545                 550                 555                 560 


Arg Cys Thr Leu Thr Asn Ile Pro Gln Thr Gln Ala Leu Leu Asn Lys 
                565                 570                 575     


Ala Lys Leu Pro Leu Gly Leu Leu Leu His Pro Phe Arg Asp Leu Thr 
            580                 585                 590         


Gln Leu Pro Val Ile Thr Ser Asn Thr Ile Val Arg Cys Arg Ser Cys 
        595                 600                 605             


Arg Thr Tyr Ile Asn Pro Phe Val Ser Phe Ile Asp Gln Arg Arg Trp 
    610                 615                 620                 


Lys Cys Asn Leu Cys Tyr Arg Val Asn Asp Val Pro Glu Glu Phe Met 
625                 630                 635                 640 


Tyr Asn Pro Leu Thr Arg Ser Tyr Gly Glu Pro His Lys Arg Pro Glu 
                645                 650                 655     


Val Gln Asn Ser Thr Val Glu Phe Ile Ala Ser Ser Asp Tyr Met Leu 
            660                 665                 670         


Arg Pro Pro Gln Pro Ala Val Tyr Leu Phe Val Leu Asp Val Ser His 
        675                 680                 685             


Asn Ala Val Glu Ala Gly Tyr Leu Thr Ile Leu Cys Gln Ser Leu Leu 
    690                 695                 700                 


Glu Asn Leu Asp Lys Leu Pro Gly Asp Ser Arg Thr Arg Ile Gly Phe 
705                 710                 715                 720 


Met Thr Phe Asp Ser Thr Ile His Phe Tyr Asn Leu Gln Glu Gly Leu 
                725                 730                 735     


Ser Gln Pro Gln Met Leu Ile Val Ser Asp Ile Asp Asp Val Phe Leu 
            740                 745                 750         


Pro Thr Pro Asp Ser Leu Leu Val Asn Leu Tyr Glu Ser Lys Glu Leu 
        755                 760                 765             


Ile Lys Asp Leu Leu Asn Ala Leu Pro Asn Met Phe Thr Asn Thr Arg 
    770                 775                 780                 


Glu Thr His Ser Ala Leu Gly Pro Ala Leu Gln Ala Ala Phe Lys Leu 
785                 790                 795                 800 


Met Ser Pro Thr Gly Gly Arg Val Ser Val Phe Gln Thr Gln Leu Pro 
                805                 810                 815     


Ser Leu Gly Ala Gly Leu Leu Gln Ser Arg Glu Asp Pro Asn Gln Arg 
            820                 825                 830         


Ser Ser Thr Lys Val Val Gln His Leu Gly Pro Ala Thr Asp Phe Tyr 
        835                 840                 845             


Lys Lys Leu Ala Leu Asp Cys Ser Gly Gln Gln Thr Ala Val Asp Leu 
    850                 855                 860                 


Phe Leu Leu Ser Ser Gln Tyr Ser Asp Leu Ala Ser Leu Ala Cys Met 
865                 870                 875                 880 


Ser Lys Tyr Ser Ala Gly Cys Ile Tyr Tyr Tyr Pro Ser Phe His Tyr 
                885                 890                 895     


Thr His Asn Pro Ser Gln Ala Glu Lys Leu Gln Lys Asp Leu Lys Arg 
            900                 905                 910         


Tyr Leu Thr Arg Lys Ile Gly Phe Glu Ala Val Met Arg Ile Arg Cys 
        915                 920                 925             


Thr Lys Gly Leu Ser Met His Thr Phe His Gly Asn Phe Phe Val Arg 
    930                 935                 940                 


Ser Thr Asp Leu Leu Ser Leu Ala Asn Ile Asn Pro Asp Ala Gly Phe 
945                 950                 955                 960 


Ala Val Gln Leu Ser Ile Glu Glu Ser Leu Thr Asp Thr Ser Leu Val 
                965                 970                 975     


Cys Phe Gln Thr Ala Leu Leu Tyr Thr Ser Ser Lys Gly Glu Arg Arg 
            980                 985                 990         


Ile Arg Val His Thr Leu Cys Leu  Pro Val Val Ser Ser  Leu Ala Asp 
        995                 1000                 1005             


Val Tyr  Ala Gly Val Asp Val  Gln Ala Ala Ile Cys  Leu Leu Ala 
    1010                 1015                 1020             


Asn Met  Ala Val Asp Arg Ser  Val Ser Ser Ser Leu  Ser Asp Ala 
    1025                 1030                 1035             


Arg Asp  Ala Leu Val Asn Ala  Val Val Asp Ser Leu  Ser Ala Tyr 
    1040                 1045                 1050             


Gly Ser  Thr Val Ser Asn Leu  Gln His Ser Ala Leu  Met Ala Pro 
    1055                 1060                 1065             


Ser Ser  Leu Lys Leu Phe Pro  Leu Tyr Val Leu Ala  Leu Leu Lys 
    1070                 1075                 1080             


Gln Lys  Ala Phe Arg Thr Gly  Thr Ser Thr Arg Leu  Asp Asp Arg 
    1085                 1090                 1095             


Val Tyr  Ala Met Cys Gln Ile  Lys Ser Gln Pro Leu  Val His Leu 
    1100                 1105                 1110             


Met Lys  Met Ile His Pro Asn  Leu Tyr Arg Ile Asp  Arg Leu Thr 
    1115                 1120                 1125             


Asp Glu  Gly Ala Val His Val  Asn Asp Arg Ile Val  Pro Gln Pro 
    1130                 1135                 1140             


Pro Leu  Gln Lys Leu Ser Ala  Glu Lys Leu Thr Arg  Glu Gly Ala 
    1145                 1150                 1155             


Phe Leu  Met Asp Cys Gly Ser  Val Phe Tyr Ile Trp  Val Gly Lys 
    1160                 1165                 1170             


Gly Cys  Asp Asn Asn Phe Ile  Glu Asp Val Leu Gly  Tyr Thr Asn 
    1175                 1180                 1185             


Phe Ala  Ser Ile Pro Gln Lys  Met Thr His Leu Pro  Glu Leu Asp 
    1190                 1195                 1200             


Thr Leu  Ser Ser Glu Arg Ala  Arg Ser Phe Ile Thr  Trp Leu Arg 
    1205                 1210                 1215             


Asp Ser  Arg Pro Leu Ser Pro  Ile Leu His Ile Val  Lys Asp Glu 
    1220                 1225                 1230             


Ser Pro  Ala Lys Ala Glu Phe  Phe Gln His Leu Ile  Glu Asp Arg 
    1235                 1240                 1245             


Thr Glu  Ala Ala Phe Ser Tyr  Tyr Glu Phe Leu Leu  His Val Gln 
    1250                 1255                 1260             


Gln Gln  Ile Cys Lys 
    1265             


<210>  4174
<211>  392
<212>  PRT
<213>  homo sapiens

<400>  4174

Met Glu Ala Pro Leu Val Ser Leu Asp Glu Glu Phe Glu Asp Leu Arg 
1               5                   10                  15      


Pro Ser Cys Ser Glu Asp Pro Glu Glu Lys Pro Gln Cys Phe Tyr Gly 
            20                  25                  30          


Ser Ser Pro His His Leu Glu Asp Pro Ser Leu Ser Glu Leu Glu Asn 
        35                  40                  45              


Phe Ser Ser Glu Ile Ile Ser Phe Lys Ser Met Glu Asp Leu Val Asn 
    50                  55                  60                  


Glu Phe Asp Glu Lys Leu Asn Val Cys Phe Arg Asn Tyr Asn Ala Lys 
65                  70                  75                  80  


Thr Glu Asn Leu Ala Pro Val Lys Asn Gln Leu Gln Ile Gln Glu Glu 
                85                  90                  95      


Glu Glu Thr Leu Gln Asp Glu Glu Val Trp Asp Ala Leu Thr Asp Asn 
            100                 105                 110         


Tyr Ile Pro Ser Leu Ser Glu Asp Trp Arg Asp Pro Asn Ile Glu Ala 
        115                 120                 125             


Leu Asn Gly Asn Cys Ser Asp Thr Glu Ile His Glu Lys Glu Glu Glu 
    130                 135                 140                 


Glu Phe Asn Glu Lys Ser Glu Asn Asp Ser Gly Ile Asn Glu Glu Pro 
145                 150                 155                 160 


Leu Leu Thr Ala Asp Gln Val Ile Glu Glu Ile Glu Glu Met Met Gln 
                165                 170                 175     


Asn Ser Pro Asp Pro Glu Glu Glu Glu Glu Val Leu Glu Glu Glu Asp 
            180                 185                 190         


Gly Gly Glu Thr Ser Ser Gln Ala Asp Ser Val Leu Leu Gln Glu Met 
        195                 200                 205             


Gln Ala Leu Thr Gln Thr Phe Asn Asn Asn Trp Ser Tyr Glu Gly Leu 
    210                 215                 220                 


Arg His Met Ser Gly Ser Glu Leu Thr Glu Leu Leu Asp Gln Val Glu 
225                 230                 235                 240 


Gly Ala Ile Arg Asp Phe Ser Glu Glu Leu Val Gln Gln Leu Ala Arg 
                245                 250                 255     


Arg Asp Glu Leu Glu Phe Glu Lys Glu Val Lys Asn Ser Phe Ile Thr 
            260                 265                 270         


Val Leu Ile Glu Val Gln Asn Lys Gln Lys Glu Gln Arg Glu Leu Met 
        275                 280                 285             


Lys Lys Arg Arg Lys Glu Lys Gly Leu Ser Leu Gln Ser Ser Arg Ile 
    290                 295                 300                 


Glu Lys Gly Asn Gln Met Pro Leu Lys Arg Phe Ser Met Glu Gly Ile 
305                 310                 315                 320 


Ser Asn Ile Leu Gln Ser Gly Ile Arg Gln Thr Phe Gly Ser Ser Gly 
                325                 330                 335     


Thr Asp Lys Gln Tyr Leu Asn Thr Val Ile Pro Tyr Glu Lys Lys Ala 
            340                 345                 350         


Ser Pro Pro Ser Val Glu Asp Leu Gln Met Leu Thr Asn Ile Leu Phe 
        355                 360                 365             


Ala Met Lys Glu Asp Asn Glu Lys Val Pro Thr Leu Leu Thr Asp Tyr 
    370                 375                 380                 


Ile Leu Lys Val Leu Cys Pro Thr 
385                 390         


<210>  4175
<211>  1905
<212>  PRT
<213>  homo sapiens

<400>  4175

Met Glu Met Glu Ala Asn Asp His Phe Asn Phe Thr Gly Leu Pro Pro 
1               5                   10                  15      


Ala Pro Ala Ala Ser Gly Leu Lys Pro Ser Pro Ser Ser Gly Glu Gly 
            20                  25                  30          


Leu Tyr Thr Asn Gly Ser Pro Met Asn Phe Pro Gln Gln Gly Lys Ser 
        35                  40                  45              


Leu Asn Gly Asp Val Asn Val Asn Gly Leu Ser Thr Val Ser His Thr 
    50                  55                  60                  


Thr Thr Ser Gly Ile Leu Asn Ser Ala Pro His Ser Ser Ser Thr Ser 
65                  70                  75                  80  


His Leu His His Pro Ser Val Ala Tyr Asp Cys Leu Trp Asn Tyr Ser 
                85                  90                  95      


Gln Tyr Pro Ser Ala Asn Pro Gly Ser Asn Leu Lys Asp Pro Pro Leu 
            100                 105                 110         


Leu Ser Gln Phe Ser Gly Gly Gln Tyr Pro Leu Asn Gly Ile Leu Gly 
        115                 120                 125             


Gly Ser Arg Gln Pro Ser Ser Pro Ser His Asn Thr Asn Leu Arg Ala 
    130                 135                 140                 


Gly Ser Gln Glu Phe Trp Ala Asn Gly Thr Gln Ser Pro Met Gly Leu 
145                 150                 155                 160 


Asn Phe Asp Ser Gln Glu Leu Tyr Asp Ser Phe Pro Asp Gln Asn Phe 
                165                 170                 175     


Glu Val Met Pro Asn Gly Pro Pro Ser Phe Phe Thr Ser Pro Gln Thr 
            180                 185                 190         


Ser Pro Met Leu Gly Ser Ser Ile Gln Thr Phe Ala Pro Ser Gln Glu 
        195                 200                 205             


Val Gly Ser Gly Ile His Pro Asp Glu Ala Ala Glu Lys Glu Met Thr 
    210                 215                 220                 


Ser Val Val Ala Glu Asn Gly Thr Gly Leu Val Gly Ser Leu Glu Leu 
225                 230                 235                 240 


Glu Glu Glu Gln Pro Glu Leu Lys Met Cys Gly Tyr Asn Gly Ser Val 
                245                 250                 255     


Pro Ser Val Glu Ser Leu His Gln Glu Val Ser Val Leu Val Pro Asp 
            260                 265                 270         


Pro Thr Val Ser Cys Leu Asp Asp Pro Ser His Leu Pro Asp Gln Leu 
        275                 280                 285             


Glu Asp Thr Pro Ile Leu Ser Glu Asp Ser Leu Glu Pro Phe Asn Ser 
    290                 295                 300                 


Leu Ala Pro Glu Pro Val Ser Gly Gly Leu Tyr Gly Ile Asp Asp Thr 
305                 310                 315                 320 


Glu Leu Met Gly Ala Glu Asp Lys Leu Pro Leu Glu Asp Ser Pro Val 
                325                 330                 335     


Ile Ser Ala Leu Asp Cys Pro Ser Leu Asn Asn Ala Thr Ala Phe Ser 
            340                 345                 350         


Leu Leu Ala Asp Asp Ser Gln Thr Ser Thr Ser Ile Phe Ala Ser Pro 
        355                 360                 365             


Thr Ser Pro Pro Val Leu Gly Glu Ser Val Leu Gln Asp Asn Ser Phe 
    370                 375                 380                 


Asp Leu Asn Asn Gly Ser Asp Ala Glu Gln Glu Glu Met Glu Thr Gln 
385                 390                 395                 400 


Ser Ser Asp Phe Pro Pro Ser Leu Thr Gln Pro Ala Pro Asp Gln Ser 
                405                 410                 415     


Ser Thr Ile Gln Leu His Pro Ala Thr Ser Pro Ala Val Ser Pro Thr 
            420                 425                 430         


Thr Ser Pro Ala Val Ser Leu Val Val Ser Pro Ala Ala Ser Pro Glu 
        435                 440                 445             


Ile Ser Pro Glu Val Cys Pro Ala Ala Ser Thr Val Val Ser Pro Ala 
    450                 455                 460                 


Val Phe Ser Val Val Ser Pro Ala Ser Ser Ala Val Leu Pro Ala Val 
465                 470                 475                 480 


Ser Leu Glu Val Pro Leu Thr Ala Ser Val Thr Ser Pro Lys Ala Ser 
                485                 490                 495     


Pro Val Thr Ser Pro Ala Ala Ala Phe Pro Thr Ala Ser Pro Ala Asn 
            500                 505                 510         


Lys Asp Val Ser Ser Phe Leu Glu Thr Thr Ala Asp Val Glu Glu Ile 
        515                 520                 525             


Thr Gly Glu Gly Leu Thr Ala Ser Gly Ser Gly Asp Val Met Arg Arg 
    530                 535                 540                 


Arg Ile Ala Thr Pro Glu Glu Val Arg Leu Pro Leu Gln His Gly Trp 
545                 550                 555                 560 


Arg Arg Glu Val Arg Ile Lys Lys Gly Ser His Arg Trp Gln Gly Glu 
                565                 570                 575     


Thr Trp Tyr Tyr Gly Pro Cys Gly Lys Arg Met Lys Gln Phe Pro Glu 
            580                 585                 590         


Val Ile Lys Tyr Leu Ser Arg Asn Val Val His Ser Val Arg Arg Glu 
        595                 600                 605             


His Phe Ser Phe Ser Pro Arg Met Pro Val Gly Asp Phe Phe Glu Glu 
    610                 615                 620                 


Arg Asp Thr Pro Glu Gly Leu Gln Trp Val Gln Leu Ser Ala Glu Glu 
625                 630                 635                 640 


Ile Pro Ser Arg Ile Gln Ala Ile Thr Gly Lys Arg Gly Arg Pro Arg 
                645                 650                 655     


Asn Thr Glu Lys Ala Lys Thr Lys Glu Val Pro Lys Val Lys Arg Gly 
            660                 665                 670         


Arg Gly Arg Pro Pro Lys Val Lys Ile Thr Glu Leu Leu Asn Lys Thr 
        675                 680                 685             


Asp Asn Arg Pro Leu Lys Lys Leu Glu Ala Gln Glu Thr Leu Asn Glu 
    690                 695                 700                 


Glu Asp Lys Ala Lys Ile Ala Lys Ser Lys Lys Lys Met Arg Gln Lys 
705                 710                 715                 720 


Val Gln Arg Gly Glu Cys Gln Thr Thr Ile Gln Gly Gln Ala Arg Asn 
                725                 730                 735     


Lys Arg Lys Gln Glu Thr Lys Ser Leu Lys Gln Lys Glu Ala Lys Lys 
            740                 745                 750         


Lys Ser Lys Ala Glu Lys Glu Lys Gly Lys Thr Lys Gln Glu Lys Leu 
        755                 760                 765             


Lys Glu Lys Val Lys Arg Glu Lys Lys Glu Lys Val Lys Met Lys Glu 
    770                 775                 780                 


Lys Glu Glu Val Thr Lys Ala Lys Pro Ala Cys Lys Ala Asp Lys Thr 
785                 790                 795                 800 


Leu Ala Thr Gln Arg Arg Leu Glu Glu Arg Gln Arg Gln Gln Met Ile 
                805                 810                 815     


Leu Glu Glu Met Lys Lys Pro Thr Glu Asp Met Cys Leu Thr Asp His 
            820                 825                 830         


Gln Pro Leu Pro Asp Phe Ser Arg Val Pro Gly Leu Thr Leu Pro Ser 
        835                 840                 845             


Gly Ala Phe Ser Asp Cys Leu Thr Ile Val Glu Phe Leu His Ser Phe 
    850                 855                 860                 


Gly Lys Val Leu Gly Phe Asp Pro Ala Lys Asp Val Pro Ser Leu Gly 
865                 870                 875                 880 


Val Leu Gln Glu Gly Leu Leu Cys Gln Gly Asp Ser Leu Gly Glu Val 
                885                 890                 895     


Gln Asp Leu Leu Val Arg Leu Leu Lys Ala Ala Leu His Asp Pro Gly 
            900                 905                 910         


Phe Pro Ser Tyr Cys Gln Ser Leu Lys Ile Leu Gly Glu Lys Val Ser 
        915                 920                 925             


Glu Ile Pro Leu Thr Arg Asp Asn Val Ser Glu Ile Leu Arg Cys Phe 
    930                 935                 940                 


Leu Met Ala Tyr Gly Val Glu Pro Ala Leu Cys Asp Arg Leu Arg Thr 
945                 950                 955                 960 


Gln Pro Phe Gln Ala Gln Pro Pro Gln Gln Lys Ala Ala Val Leu Ala 
                965                 970                 975     


Phe Leu Val His Glu Leu Asn Gly Ser Thr Leu Ile Ile Asn Glu Ile 
            980                 985                 990         


Asp Lys Thr Leu Glu Ser Met Ser  Ser Tyr Arg Lys Asn  Lys Trp Ile 
        995                 1000                 1005             


Val Glu  Gly Arg Leu Arg Arg  Leu Lys Thr Val Leu  Ala Lys Arg 
    1010                 1015                 1020             


Thr Gly  Arg Ser Glu Val Glu  Met Glu Gly Pro Glu  Glu Cys Leu 
    1025                 1030                 1035             


Gly Arg  Arg Arg Ser Ser Arg  Ile Met Glu Glu Thr  Ser Gly Met 
    1040                 1045                 1050             


Glu Glu  Glu Glu Glu Glu Glu  Ser Ile Ala Ala Val  Pro Gly Arg 
    1055                 1060                 1065             


Arg Gly  Arg Arg Asp Gly Glu  Val Asp Ala Thr Ala  Ser Ser Ile 
    1070                 1075                 1080             


Pro Glu  Leu Glu Arg Gln Ile  Glu Lys Leu Ser Lys  Arg Gln Leu 
    1085                 1090                 1095             


Phe Phe  Arg Lys Lys Leu Leu  His Ser Ser Gln Met  Leu Arg Ala 
    1100                 1105                 1110             


Val Ser  Leu Gly Gln Asp Arg  Tyr Arg Arg Arg Tyr  Trp Val Leu 
    1115                 1120                 1125             


Pro Tyr  Leu Ala Gly Ile Phe  Val Glu Gly Thr Glu  Gly Asn Leu 
    1130                 1135                 1140             


Val Pro  Glu Glu Val Ile Lys  Lys Glu Thr Asp Ser  Leu Lys Val 
    1145                 1150                 1155             


Ala Ala  His Ala Ser Leu Asn  Pro Ala Leu Phe Ser  Met Lys Met 
    1160                 1165                 1170             


Glu Leu  Ala Gly Ser Asn Thr  Thr Ala Ser Ser Pro  Ala Arg Ala 
    1175                 1180                 1185             


Arg Gly  Arg Pro Arg Lys Thr  Lys Pro Gly Ser Met  Gln Pro Arg 
    1190                 1195                 1200             


His Leu  Lys Ser Pro Val Arg  Gly Gln Asp Ser Glu  Gln Pro Gln 
    1205                 1210                 1215             


Ala Gln  Leu Gln Pro Glu Ala  Gln Leu His Ala Pro  Ala Gln Pro 
    1220                 1225                 1230             


Gln Pro  Gln Leu Gln Leu Gln  Leu Gln Ser His Lys  Gly Phe Leu 
    1235                 1240                 1245             


Glu Gln  Glu Gly Ser Pro Leu  Ser Leu Gly Gln Ser  Gln His Asp 
    1250                 1255                 1260             


Leu Ser  Gln Ser Ala Phe Leu  Ser Trp Leu Ser Gln  Thr Gln Ser 
    1265                 1270                 1275             


His Ser  Ser Leu Leu Ser Ser  Ser Val Leu Thr Pro  Asp Ser Ser 
    1280                 1285                 1290             


Pro Gly  Lys Leu Asp Pro Ala  Pro Ser Gln Pro Pro  Glu Glu Pro 
    1295                 1300                 1305             


Glu Pro  Asp Glu Ala Glu Ser  Ser Pro Asp Pro Gln  Ala Leu Trp 
    1310                 1315                 1320             


Phe Asn  Ile Ser Ala Gln Met  Pro Cys Asn Ala Ala  Pro Thr Pro 
    1325                 1330                 1335             


Pro Pro  Ala Val Ser Glu Asp  Gln Pro Thr Pro Ser  Pro Gln Gln 
    1340                 1345                 1350             


Leu Ala  Ser Ser Lys Pro Met  Asn Arg Pro Ser Ala  Ala Asn Pro 
    1355                 1360                 1365             


Cys Ser  Pro Val Gln Phe Ser  Ser Thr Pro Leu Ala  Gly Leu Ala 
    1370                 1375                 1380             


Pro Lys  Arg Arg Ala Gly Asp  Pro Gly Glu Met Pro  Gln Ser Pro 
    1385                 1390                 1395             


Thr Gly  Leu Gly Gln Pro Lys  Arg Arg Gly Arg Pro  Pro Ser Lys 
    1400                 1405                 1410             


Phe Phe  Lys Gln Met Glu Gln  Arg Tyr Leu Thr Gln  Leu Thr Ala 
    1415                 1420                 1425             


Gln Pro  Val Pro Pro Glu Met  Cys Ser Gly Trp Trp  Trp Ile Arg 
    1430                 1435                 1440             


Asp Pro  Glu Met Leu Asp Ala  Met Leu Lys Ala Leu  His Pro Arg 
    1445                 1450                 1455             


Gly Ile  Arg Glu Lys Ala Leu  His Lys His Leu Asn  Lys His Arg 
    1460                 1465                 1470             


Asp Phe  Leu Gln Glu Val Cys  Leu Arg Pro Ser Ala  Asp Pro Ile 
    1475                 1480                 1485             


Phe Glu  Pro Arg Gln Leu Pro  Ala Phe Gln Glu Gly  Ile Met Ser 
    1490                 1495                 1500             


Trp Ser  Pro Lys Glu Lys Thr  Tyr Glu Thr Asp Leu  Ala Val Leu 
    1505                 1510                 1515             


Gln Trp  Val Glu Glu Leu Glu  Gln Arg Val Ile Met  Ser Asp Leu 
    1520                 1525                 1530             


Gln Ile  Arg Gly Trp Thr Cys  Pro Ser Pro Asp Ser  Thr Arg Glu 
    1535                 1540                 1545             


Asp Leu  Ala Tyr Cys Glu His  Leu Ser Asp Ser Gln  Glu Asp Ile 
    1550                 1555                 1560             


Thr Trp  Arg Gly Arg Gly Arg  Glu Gly Leu Ala Pro  Gln Arg Lys 
    1565                 1570                 1575             


Thr Thr  Asn Pro Leu Asp Leu  Ala Val Met Arg Leu  Ala Ala Leu 
    1580                 1585                 1590             


Glu Gln  Asn Val Glu Arg Arg  Tyr Leu Arg Glu Pro  Leu Trp Pro 
    1595                 1600                 1605             


Thr His  Glu Val Val Leu Glu  Lys Ala Leu Leu Ser  Thr Pro Asn 
    1610                 1615                 1620             


Gly Ala  Pro Glu Gly Thr Thr  Thr Glu Ile Ser Tyr  Glu Ile Thr 
    1625                 1630                 1635             


Pro Arg  Ile Arg Val Trp Arg  Gln Thr Leu Glu Arg  Cys Arg Ser 
    1640                 1645                 1650             


Ala Ala  Gln Val Cys Leu Cys  Leu Gly Gln Leu Glu  Arg Ser Ile 
    1655                 1660                 1665             


Ala Trp  Glu Lys Ser Val Asn  Lys Val Thr Cys Leu  Val Cys Arg 
    1670                 1675                 1680             


Lys Gly  Asp Asn Asp Glu Phe  Leu Leu Leu Cys Asp  Gly Cys Asp 
    1685                 1690                 1695             


Arg Gly  Cys His Ile Tyr Cys  His Arg Pro Lys Met  Glu Ala Val 
    1700                 1705                 1710             


Pro Glu  Gly Asp Trp Phe Cys  Thr Val Cys Leu Ala  Gln Gln Val 
    1715                 1720                 1725             


Glu Gly  Glu Phe Thr Gln Lys  Pro Gly Phe Pro Lys  Arg Gly Gln 
    1730                 1735                 1740             


Lys Arg  Lys Ser Gly Tyr Ser  Leu Asn Phe Ser Glu  Gly Asp Gly 
    1745                 1750                 1755             


Arg Arg  Arg Arg Val Leu Leu  Arg Gly Arg Glu Ser  Pro Ala Ala 
    1760                 1765                 1770             


Gly Pro  Arg Tyr Ser Glu Glu  Gly Leu Ser Pro Ser  Lys Arg Arg 
    1775                 1780                 1785             


Arg Leu  Ser Met Arg Asn His  His Ser Asp Leu Thr  Phe Cys Glu 
    1790                 1795                 1800             


Ile Ile  Leu Met Glu Met Glu  Ser His Asp Ala Ala  Trp Pro Phe 
    1805                 1810                 1815             


Leu Glu  Pro Val Asn Pro Arg  Leu Val Ser Gly Tyr  Arg Arg Ile 
    1820                 1825                 1830             


Ile Lys  Asn Pro Met Asp Phe  Ser Thr Met Arg Glu  Arg Leu Leu 
    1835                 1840                 1845             


Arg Gly  Gly Tyr Thr Ser Ser  Glu Glu Phe Ala Ala  Asp Ala Leu 
    1850                 1855                 1860             


Leu Val  Phe Asp Asn Cys Gln  Thr Phe Asn Glu Asp  Asp Ser Glu 
    1865                 1870                 1875             


Val Gly  Lys Ala Gly His Ile  Met Arg Arg Phe Phe  Glu Ser Arg 
    1880                 1885                 1890             


Trp Glu  Glu Phe Tyr Gln Gly  Lys Gln Ala Asn Leu  
    1895                 1900                 1905 


<210>  4176
<211>  1393
<212>  PRT
<213>  homo sapiens

<400>  4176

Met Val Glu Pro Gly Gln Asp Leu Leu Leu Ala Ala Leu Ser Glu Ser 
1               5                   10                  15      


Gly Ile Ser Pro Asn Asp Leu Phe Asp Ile Asp Gly Gly Asp Ala Gly 
            20                  25                  30          


Leu Ala Thr Pro Met Pro Thr Pro Ser Val Gln Gln Ser Val Pro Leu 
        35                  40                  45              


Ser Ala Leu Glu Leu Gly Leu Glu Thr Glu Ala Ala Val Pro Val Lys 
    50                  55                  60                  


Gln Glu Pro Glu Thr Val Pro Thr Pro Ala Leu Leu Asn Val Arg Gln 
65                  70                  75                  80  


Gln Pro Pro Ser Thr Thr Thr Phe Val Leu Asn Gln Ile Asn His Leu 
                85                  90                  95      


Pro Pro Leu Gly Ser Thr Ile Val Met Thr Lys Thr Pro Pro Val Thr 
            100                 105                 110         


Thr Asn Arg Gln Thr Ile Thr Leu Thr Lys Phe Ile Gln Thr Thr Ala 
        115                 120                 125             


Ser Thr Arg Pro Ser Val Ser Ala Pro Thr Val Arg Asn Ala Met Thr 
    130                 135                 140                 


Ser Ala Pro Ser Lys Asp Gln Val Gln Leu Lys Asp Leu Leu Lys Asn 
145                 150                 155                 160 


Asn Ser Leu Asn Glu Leu Met Lys Leu Lys Pro Pro Ala Asn Ile Ala 
                165                 170                 175     


Gln Pro Val Ala Thr Ala Ala Thr Asp Val Ser Asn Gly Thr Val Lys 
            180                 185                 190         


Lys Glu Ser Ser Asn Lys Glu Gly Ala Arg Met Trp Ile Asn Asp Met 
        195                 200                 205             


Lys Met Arg Ser Phe Ser Pro Thr Met Lys Val Pro Val Val Lys Glu 
    210                 215                 220                 


Asp Asp Glu Pro Glu Glu Glu Asp Glu Glu Glu Met Gly His Ala Glu 
225                 230                 235                 240 


Thr Tyr Ala Glu Tyr Met Pro Ile Lys Leu Lys Ile Gly Leu Arg His 
                245                 250                 255     


Pro Asp Ala Val Val Glu Thr Ser Ser Leu Ser Ser Val Thr Pro Pro 
            260                 265                 270         


Asp Val Trp Tyr Lys Thr Ser Ile Ser Glu Glu Thr Ile Asp Asn Gly 
        275                 280                 285             


Trp Leu Ser Ala Leu Gln Leu Glu Ala Ile Thr Tyr Ala Ala Gln Gln 
    290                 295                 300                 


His Glu Thr Phe Leu Pro Asn Gly Asp Arg Ala Gly Phe Leu Ile Gly 
305                 310                 315                 320 


Asp Gly Ala Gly Val Gly Lys Gly Arg Thr Ile Ala Gly Ile Ile Tyr 
                325                 330                 335     


Glu Asn Tyr Leu Leu Ser Arg Lys Arg Ala Leu Trp Phe Ser Val Ser 
            340                 345                 350         


Asn Asp Leu Lys Tyr Asp Ala Glu Arg Asp Leu Arg Asp Ile Gly Ala 
        355                 360                 365             


Lys Asn Ile Leu Val His Ser Leu Asn Lys Phe Lys Tyr Gly Lys Ile 
    370                 375                 380                 


Ser Ser Lys His Asn Gly Ser Val Lys Lys Gly Val Ile Phe Ala Thr 
385                 390                 395                 400 


Tyr Ser Ser Leu Ile Gly Glu Ser Gln Ser Gly Gly Lys Tyr Lys Thr 
                405                 410                 415     


Arg Leu Lys Gln Leu Leu His Trp Cys Gly Asp Asp Phe Asp Gly Val 
            420                 425                 430         


Ile Val Phe Asp Glu Cys His Lys Ala Lys Asn Leu Cys Pro Val Gly 
        435                 440                 445             


Ser Ser Lys Pro Thr Lys Thr Gly Leu Ala Val Leu Glu Leu Gln Asn 
    450                 455                 460                 


Lys Leu Pro Lys Ala Arg Val Val Tyr Ala Ser Ala Thr Gly Ala Ser 
465                 470                 475                 480 


Glu Pro Arg Asn Met Ala Tyr Met Asn Arg Leu Gly Ile Trp Gly Glu 
                485                 490                 495     


Gly Thr Pro Phe Arg Glu Phe Ser Asp Phe Ile Gln Ala Val Glu Arg 
            500                 505                 510         


Arg Gly Val Gly Ala Met Glu Ile Val Ala Met Asp Met Lys Leu Arg 
        515                 520                 525             


Gly Met Tyr Ile Ala Arg Gln Leu Ser Phe Thr Gly Val Thr Phe Lys 
    530                 535                 540                 


Ile Glu Glu Val Leu Leu Ser Gln Ser Tyr Val Lys Met Tyr Asn Lys 
545                 550                 555                 560 


Ala Val Lys Leu Trp Val Ile Ala Arg Glu Arg Phe Gln Gln Ala Ala 
                565                 570                 575     


Asp Leu Ile Asp Ala Glu Gln Arg Met Lys Lys Ser Met Trp Gly Gln 
            580                 585                 590         


Phe Trp Ser Ala His Gln Arg Phe Phe Lys Tyr Leu Cys Ile Ala Ser 
        595                 600                 605             


Lys Val Lys Arg Val Val Gln Leu Ala Arg Glu Glu Ile Lys Asn Gly 
    610                 615                 620                 


Lys Cys Val Val Ile Gly Leu Gln Ser Thr Gly Glu Ala Arg Thr Leu 
625                 630                 635                 640 


Glu Ala Leu Glu Glu Gly Gly Gly Glu Leu Asn Asp Phe Val Ser Thr 
                645                 650                 655     


Ala Lys Gly Val Leu Gln Ser Leu Ile Glu Lys His Phe Pro Ala Pro 
            660                 665                 670         


Asp Arg Lys Lys Leu Tyr Ser Leu Leu Gly Ile Asp Leu Thr Ala Pro 
        675                 680                 685             


Ser Asn Asn Ser Ser Pro Arg Asp Ser Pro Cys Lys Glu Asn Lys Ile 
    690                 695                 700                 


Lys Lys Arg Lys Gly Glu Glu Ile Thr Arg Glu Ala Lys Lys Ala Arg 
705                 710                 715                 720 


Lys Val Gly Gly Leu Thr Gly Ser Ser Ser Asp Asp Ser Gly Ser Glu 
                725                 730                 735     


Ser Asp Ala Ser Asp Asn Glu Glu Ser Asp Tyr Glu Ser Ser Lys Asn 
            740                 745                 750         


Met Ser Ser Gly Asp Asp Asp Asp Phe Asn Pro Phe Leu Asp Glu Ser 
        755                 760                 765             


Asn Glu Asp Asp Glu Asn Asp Pro Trp Leu Ile Arg Lys Asp His Lys 
    770                 775                 780                 


Lys Asn Lys Glu Lys Lys Lys Lys Lys Ser Ile Asp Pro Asp Ser Ile 
785                 790                 795                 800 


Gln Ser Ala Leu Leu Ala Ser Gly Leu Gly Ser Lys Arg Pro Ser Phe 
                805                 810                 815     


Ser Ser Thr Pro Val Ile Ser Pro Ala Pro Asn Ser Thr Pro Ala Asn 
            820                 825                 830         


Ser Asn Thr Asn Ser Asn Ser Ser Leu Ile Thr Ser Gln Asp Ala Val 
        835                 840                 845             


Glu Arg Ala Gln Gln Met Lys Lys Asp Leu Leu Asp Lys Leu Glu Lys 
    850                 855                 860                 


Leu Ala Glu Asp Leu Pro Pro Asn Thr Leu Asp Glu Leu Ile Asp Glu 
865                 870                 875                 880 


Leu Gly Gly Pro Glu Asn Val Ala Glu Met Thr Gly Arg Lys Gly Arg 
                885                 890                 895     


Val Val Ser Asn Asp Asp Gly Ser Ile Ser Tyr Glu Ser Arg Ser Glu 
            900                 905                 910         


Leu Asp Val Pro Val Glu Ile Leu Asn Ile Thr Glu Lys Gln Arg Phe 
        915                 920                 925             


Met Asp Gly Asp Lys Asn Ile Ala Ile Ile Ser Glu Ala Ala Ser Ser 
    930                 935                 940                 


Gly Ile Ser Leu Gln Ala Asp Arg Arg Ala Lys Asn Gln Arg Arg Arg 
945                 950                 955                 960 


Val His Met Thr Leu Glu Leu Pro Trp Ser Ala Asp Arg Ala Ile Gln 
                965                 970                 975     


Gln Phe Gly Arg Thr His Arg Ser Asn Gln Val Thr Ala Pro Glu Tyr 
            980                 985                 990         


Val Phe Leu Ile Ser Glu Leu Ala  Gly Glu Gln Arg Phe  Ala Ser Ile 
        995                 1000                 1005             


Val Ala  Lys Arg Leu Glu Ser  Leu Gly Ala Leu Thr  His Gly Asp 
    1010                 1015                 1020             


Arg Arg  Ala Thr Glu Ser Arg  Asp Leu Ser Arg Phe  Asn Phe Asp 
    1025                 1030                 1035             


Asn Lys  Tyr Gly Arg Asn Ala  Leu Glu Ile Val Met  Lys Ser Ile 
    1040                 1045                 1050             


Val Asn  Leu Asp Ser Pro Met  Val Ser Pro Pro Pro  Asp Tyr Pro 
    1055                 1060                 1065             


Gly Glu  Phe Phe Lys Asp Val  Arg Gln Gly Leu Ile  Gly Val Gly 
    1070                 1075                 1080             


Leu Ile  Asn Val Glu Asp Arg  Ser Gly Ile Leu Thr  Leu Asp Lys 
    1085                 1090                 1095             


Asp Tyr  Asn Asn Ile Gly Lys  Phe Leu Asn Arg Ile  Leu Gly Met 
    1100                 1105                 1110             


Glu Val  His Gln Gln Asn Ala  Leu Phe Gln Tyr Phe  Ala Asp Thr 
    1115                 1120                 1125             


Leu Thr  Ala Val Val Gln Asn  Ala Lys Lys Asn Gly  Arg Tyr Asp 
    1130                 1135                 1140             


Met Gly  Ile Leu Asp Leu Gly  Ser Gly Asp Glu Lys  Val Arg Lys 
    1145                 1150                 1155             


Ser Asp  Val Lys Lys Phe Leu  Thr Pro Gly Tyr Ser  Thr Ser Gly 
    1160                 1165                 1170             


His Val  Glu Leu Tyr Thr Ile  Ser Val Glu Arg Gly  Met Ser Trp 
    1175                 1180                 1185             


Glu Glu  Ala Thr Lys Ile Trp  Ala Glu Leu Thr Gly  Pro Asp Asp 
    1190                 1195                 1200             


Gly Phe  Tyr Leu Ser Leu Gln  Ile Arg Asn Asn Lys  Lys Thr Ala 
    1205                 1210                 1215             


Ile Leu  Val Lys Glu Val Asn  Pro Lys Lys Lys Leu  Phe Leu Val 
    1220                 1225                 1230             


Tyr Arg  Pro Asn Thr Gly Lys  Gln Leu Lys Leu Glu  Ile Tyr Ala 
    1235                 1240                 1245             


Asp Leu  Lys Lys Lys Tyr Lys  Lys Val Val Ser Asp  Asp Ala Leu 
    1250                 1255                 1260             


Met His  Trp Leu Asp Gln Tyr  Asn Ser Ser Ala Asp  Thr Cys Thr 
    1265                 1270                 1275             


His Ala  Tyr Trp Arg Gly Asn  Cys Lys Lys Ala Ser  Leu Gly Leu 
    1280                 1285                 1290             


Val Cys  Glu Ile Gly Leu Arg  Cys Arg Thr Tyr Tyr  Val Leu Cys 
    1295                 1300                 1305             


Gly Ser  Val Leu Ser Val Trp  Thr Lys Val Glu Gly  Val Leu Ala 
    1310                 1315                 1320             


Ser Val  Ser Gly Thr Asn Val  Lys Met Gln Ile Val  Arg Leu Arg 
    1325                 1330                 1335             


Thr Glu  Asp Gly Gln Arg Ile  Val Gly Leu Ile Ile  Pro Ala Asn 
    1340                 1345                 1350             


Cys Val  Ser Pro Leu Val Asn  Leu Leu Ser Thr Ser  Asp Gln Ser 
    1355                 1360                 1365             


Gln Gln  Leu Ala Val Gln Gln  Lys Gln Leu Trp Gln  Gln His His 
    1370                 1375                 1380             


Pro Gln  Ser Ile Thr Asn Leu  Ser Asn Ala 
    1385                 1390             


<210>  4177
<211>  393
<212>  PRT
<213>  homo sapiens

<400>  4177

Met Ala Ser Gly Arg Ala Arg Cys Thr Arg Lys Leu Arg Asn Trp Val 
1               5                   10                  15      


Val Glu Gln Val Glu Ser Gly Gln Phe Pro Gly Val Cys Trp Asp Asp 
            20                  25                  30          


Thr Ala Lys Thr Met Phe Arg Ile Pro Trp Lys His Ala Gly Lys Gln 
        35                  40                  45              


Asp Phe Arg Glu Asp Gln Asp Ala Ala Phe Phe Lys Ala Trp Ala Ile 
    50                  55                  60                  


Phe Lys Gly Lys Tyr Lys Glu Gly Asp Thr Gly Gly Pro Ala Val Trp 
65                  70                  75                  80  


Lys Thr Arg Leu Arg Cys Ala Leu Asn Lys Ser Ser Glu Phe Lys Glu 
                85                  90                  95      


Val Pro Glu Arg Gly Arg Met Asp Val Ala Glu Pro Tyr Lys Val Tyr 
            100                 105                 110         


Gln Leu Leu Pro Pro Gly Ile Val Ser Gly Gln Pro Gly Thr Gln Lys 
        115                 120                 125             


Val Pro Ser Lys Arg Gln His Ser Ser Val Ser Ser Glu Arg Lys Glu 
    130                 135                 140                 


Glu Glu Asp Ala Met Gln Asn Cys Thr Leu Ser Pro Ser Val Leu Gln 
145                 150                 155                 160 


Asp Ser Leu Asn Asn Glu Glu Glu Gly Ala Ser Gly Gly Ala Val His 
                165                 170                 175     


Ser Asp Ile Gly Ser Ser Ser Ser Ser Ser Ser Pro Glu Pro Gln Glu 
            180                 185                 190         


Val Thr Asp Thr Thr Glu Ala Pro Phe Gln Gly Asp Gln Arg Ser Leu 
        195                 200                 205             


Glu Phe Leu Leu Pro Pro Glu Pro Asp Tyr Ser Leu Leu Leu Thr Phe 
    210                 215                 220                 


Ile Tyr Asn Gly Arg Val Val Gly Glu Ala Gln Val Gln Ser Leu Asp 
225                 230                 235                 240 


Cys Arg Leu Val Ala Glu Pro Ser Gly Ser Glu Ser Ser Met Glu Gln 
                245                 250                 255     


Val Leu Phe Pro Lys Pro Gly Pro Leu Glu Pro Thr Gln Arg Leu Leu 
            260                 265                 270         


Ser Gln Leu Glu Arg Gly Ile Leu Val Ala Ser Asn Pro Arg Gly Leu 
        275                 280                 285             


Phe Val Gln Arg Leu Cys Pro Ile Pro Ile Ser Trp Asn Ala Pro Gln 
    290                 295                 300                 


Ala Pro Pro Gly Pro Gly Pro His Leu Leu Pro Ser Asn Glu Cys Val 
305                 310                 315                 320 


Glu Leu Phe Arg Thr Ala Tyr Phe Cys Arg Asp Leu Val Arg Tyr Phe 
                325                 330                 335     


Gln Gly Leu Gly Pro Pro Pro Lys Phe Gln Val Thr Leu Asn Phe Trp 
            340                 345                 350         


Glu Glu Ser His Gly Ser Ser His Thr Pro Gln Asn Leu Ile Thr Val 
        355                 360                 365             


Lys Met Glu Gln Ala Phe Ala Arg Tyr Leu Leu Glu Gln Thr Pro Glu 
    370                 375                 380                 


Gln Gln Ala Ala Ile Leu Ser Leu Val 
385                 390             


<210>  4178
<211>  163
<212>  PRT
<213>  homo sapiens

<400>  4178

Met Met Pro Gly Gln Ile Pro Asp Pro Ser Val Thr Thr Gly Ser Leu 
1               5                   10                  15      


Pro Gly Leu Gly Pro Leu Thr Gly Leu Pro Ser Ser Ala Leu Thr Val 
            20                  25                  30          


Glu Glu Leu Lys Tyr Ala Asp Ile Arg Asn Leu Gly Ala Met Ile Ala 
        35                  40                  45              


Pro Leu His Phe Leu Glu Val Lys Leu Gly Lys Arg Pro Gln Pro Val 
    50                  55                  60                  


Lys Ser Glu Leu Asp Glu Glu Glu Glu Arg Arg Lys Arg Arg Arg Glu 
65                  70                  75                  80  


Lys Asn Lys Val Ala Ala Ala Arg Cys Arg Asn Lys Lys Lys Glu Arg 
                85                  90                  95      


Thr Glu Phe Leu Gln Arg Glu Ser Glu Arg Leu Glu Leu Met Asn Ala 
            100                 105                 110         


Glu Leu Lys Thr Gln Ile Glu Glu Leu Lys Gln Glu Arg Gln Gln Leu 
        115                 120                 125             


Ile Leu Met Leu Asn Arg His Arg Pro Thr Cys Ile Val Arg Thr Asp 
    130                 135                 140                 


Ser Val Lys Thr Pro Glu Ser Glu Gly Asn Pro Leu Leu Glu Gln Leu 
145                 150                 155                 160 


Glu Lys Lys 
            


<210>  4179
<211>  350
<212>  PRT
<213>  homo sapiens

<400>  4179

Met Ser His Gln Thr Gly Ile Gln Ala Ser Glu Asp Val Lys Glu Ile 
1               5                   10                  15      


Phe Ala Arg Ala Arg Asn Gly Lys Tyr Arg Leu Leu Lys Ile Ser Ile 
            20                  25                  30          


Glu Asn Glu Gln Leu Val Ile Gly Ser Tyr Ser Gln Pro Ser Asp Ser 
        35                  40                  45              


Trp Asp Lys Asp Tyr Asp Ser Phe Val Leu Pro Leu Leu Glu Asp Lys 
    50                  55                  60                  


Gln Pro Cys Tyr Ile Leu Phe Arg Leu Asp Ser Gln Asn Ala Gln Gly 
65                  70                  75                  80  


Tyr Glu Trp Ile Phe Ile Ala Trp Ser Pro Asp His Ser His Val Arg 
                85                  90                  95      


Gln Lys Met Leu Tyr Ala Ala Thr Arg Ala Thr Leu Lys Lys Glu Phe 
            100                 105                 110         


Gly Gly Gly His Ile Lys Asp Glu Val Phe Gly Thr Val Lys Glu Asp 
        115                 120                 125             


Val Ser Leu His Gly Tyr Lys Lys Tyr Leu Leu Ser Gln Ser Ser Pro 
    130                 135                 140                 


Ala Pro Leu Thr Ala Ala Glu Glu Glu Leu Arg Gln Ile Lys Ile Asn 
145                 150                 155                 160 


Glu Val Gln Thr Asp Val Gly Val Asp Thr Lys His Gln Thr Leu Gln 
                165                 170                 175     


Gly Val Ala Phe Pro Ile Ser Arg Glu Ala Phe Gln Ala Leu Glu Lys 
            180                 185                 190         


Leu Asn Asn Arg Gln Leu Asn Tyr Val Gln Leu Glu Ile Asp Ile Lys 
        195                 200                 205             


Asn Glu Ile Ile Ile Leu Ala Asn Thr Thr Asn Thr Glu Leu Lys Asp 
    210                 215                 220                 


Leu Pro Lys Arg Ile Pro Lys Asp Ser Ala Arg Tyr His Phe Phe Leu 
225                 230                 235                 240 


Tyr Lys His Ser His Glu Gly Asp Tyr Leu Glu Ser Ile Val Phe Ile 
                245                 250                 255     


Tyr Ser Met Pro Gly Tyr Thr Cys Ser Ile Arg Glu Arg Met Leu Tyr 
            260                 265                 270         


Ser Ser Cys Lys Ser Arg Leu Leu Glu Ile Val Glu Arg Gln Leu Gln 
        275                 280                 285             


Met Asp Val Ile Arg Lys Ile Glu Ile Asp Asn Gly Asp Glu Leu Thr 
    290                 295                 300                 


Ala Asp Phe Leu Tyr Glu Glu Val His Pro Lys Gln His Ala His Lys 
305                 310                 315                 320 


Gln Ser Phe Ala Lys Pro Lys Gly Pro Ala Gly Lys Arg Gly Ile Arg 
                325                 330                 335     


Arg Leu Ile Arg Gly Pro Ala Glu Thr Glu Ala Thr Thr Asp 
            340                 345                 350 


<210>  4180
<211>  348
<212>  PRT
<213>  homo sapiens

<400>  4180

Met Gly Lys Asp Tyr Tyr Lys Ile Leu Gly Ile Pro Ser Gly Ala Asn 
1               5                   10                  15      


Glu Asp Glu Ile Lys Lys Ala Tyr Arg Lys Met Ala Leu Lys Tyr His 
            20                  25                  30          


Pro Asp Lys Asn Lys Glu Pro Asn Ala Glu Glu Lys Phe Lys Glu Ile 
        35                  40                  45              


Ala Glu Ala Tyr Asp Val Leu Ser Asp Pro Lys Lys Arg Gly Leu Tyr 
    50                  55                  60                  


Asp Gln Tyr Gly Glu Glu Gly Leu Lys Thr Gly Gly Gly Thr Ser Gly 
65                  70                  75                  80  


Gly Ser Ser Gly Ser Phe His Tyr Thr Phe His Gly Asp Pro His Ala 
                85                  90                  95      


Thr Phe Ala Ser Phe Phe Gly Gly Ser Asn Pro Phe Asp Ile Phe Phe 
            100                 105                 110         


Ala Ser Ser Arg Ser Thr Arg Pro Phe Ser Gly Phe Asp Pro Asp Asp 
        115                 120                 125             


Met Asp Val Asp Glu Asp Glu Asp Pro Phe Gly Ala Phe Gly Arg Phe 
    130                 135                 140                 


Gly Phe Asn Gly Leu Ser Arg Gly Pro Arg Arg Ala Pro Glu Pro Leu 
145                 150                 155                 160 


Tyr Pro Arg Arg Lys Val Gln Asp Pro Pro Val Val His Glu Leu Arg 
                165                 170                 175     


Val Ser Leu Glu Glu Ile Tyr His Gly Ser Thr Lys Arg Met Lys Ile 
            180                 185                 190         


Thr Arg Arg Arg Leu Asn Pro Asp Gly Arg Thr Val Arg Thr Glu Asp 
        195                 200                 205             


Lys Ile Leu His Ile Val Ile Lys Arg Gly Trp Lys Glu Gly Thr Lys 
    210                 215                 220                 


Ile Thr Phe Pro Lys Glu Gly Asp Ala Thr Pro Asp Asn Ile Pro Ala 
225                 230                 235                 240 


Asp Ile Val Phe Val Leu Lys Asp Lys Pro His Ala His Phe Arg Arg 
                245                 250                 255     


Asp Gly Thr Asn Val Leu Tyr Ser Ala Leu Ile Ser Leu Lys Glu Ala 
            260                 265                 270         


Leu Cys Gly Cys Thr Val Asn Ile Pro Thr Ile Asp Gly Arg Val Ile 
        275                 280                 285             


Pro Leu Pro Cys Asn Asp Val Ile Lys Pro Gly Thr Val Lys Arg Leu 
    290                 295                 300                 


Arg Gly Glu Gly Leu Pro Phe Pro Lys Val Pro Thr Gln Arg Gly Asp 
305                 310                 315                 320 


Leu Ile Val Glu Phe Lys Val Arg Phe Pro Asp Arg Leu Thr Pro Gln 
                325                 330                 335     


Thr Arg Gln Ile Leu Lys Gln His Leu Pro Cys Ser 
            340                 345             


<210>  4181
<211>  144
<212>  PRT
<213>  homo sapiens

<400>  4181

Met Pro Lys Asn Lys Gly Lys Gly Gly Lys Asn Arg Arg Arg Gly Lys 
1               5                   10                  15      


Asn Glu Asn Glu Ser Glu Lys Arg Glu Leu Val Phe Lys Glu Asp Gly 
            20                  25                  30          


Gln Glu Tyr Ala Gln Val Ile Lys Met Leu Gly Asn Gly Arg Leu Glu 
        35                  40                  45              


Ala Met Cys Phe Asp Gly Val Lys Arg Leu Cys His Ile Arg Gly Lys 
    50                  55                  60                  


Leu Arg Lys Lys Val Trp Ile Asn Thr Ser Asp Ile Ile Leu Val Gly 
65                  70                  75                  80  


Leu Arg Asp Tyr Gln Asp Asn Lys Ala Asp Val Ile Leu Lys Tyr Asn 
                85                  90                  95      


Ala Asp Glu Ala Arg Ser Leu Lys Ala Tyr Gly Glu Leu Pro Glu His 
            100                 105                 110         


Ala Lys Ile Asn Glu Thr Asp Thr Phe Gly Pro Gly Asp Asp Asp Glu 
        115                 120                 125             


Ile Gln Phe Asp Asp Ile Gly Asp Asp Asp Glu Asp Ile Asp Asp Ile 
    130                 135                 140                 


<210>  4182
<211>  371
<212>  PRT
<213>  homo sapiens

<400>  4182

Met Ala Ala Thr Cys Glu Ile Ser Asn Ile Phe Ser Asn Tyr Phe Ser 
1               5                   10                  15      


Ala Met Tyr Ser Ser Glu Asp Ser Thr Leu Ala Ser Val Pro Pro Ala 
            20                  25                  30          


Ala Thr Phe Gly Ala Asp Asp Leu Val Leu Thr Leu Ser Asn Pro Gln 
        35                  40                  45              


Met Ser Leu Glu Gly Thr Glu Lys Ala Ser Trp Leu Gly Glu Gln Pro 
    50                  55                  60                  


Gln Phe Trp Ser Lys Thr Gln Val Leu Asp Trp Ile Ser Tyr Gln Val 
65                  70                  75                  80  


Glu Lys Asn Lys Tyr Asp Ala Ser Ala Ile Asp Phe Ser Arg Cys Asp 
                85                  90                  95      


Met Asp Gly Ala Thr Leu Cys Asn Cys Ala Leu Glu Glu Leu Arg Leu 
            100                 105                 110         


Val Phe Gly Pro Leu Gly Asp Gln Leu His Ala Gln Leu Arg Asp Leu 
        115                 120                 125             


Thr Ser Ser Ser Ser Asp Glu Leu Ser Trp Ile Ile Glu Leu Leu Glu 
    130                 135                 140                 


Lys Asp Gly Met Ala Phe Gln Glu Ala Leu Asp Pro Gly Pro Phe Asp 
145                 150                 155                 160 


Gln Gly Ser Pro Phe Ala Gln Glu Leu Leu Asp Asp Gly Gln Gln Ala 
                165                 170                 175     


Ser Pro Tyr His Pro Gly Ser Cys Gly Ala Gly Ala Pro Ser Pro Gly 
            180                 185                 190         


Ser Ser Asp Val Ser Thr Ala Gly Thr Gly Ala Ser Arg Ser Ser His 
        195                 200                 205             


Ser Ser Asp Ser Gly Gly Ser Asp Val Asp Leu Asp Pro Thr Asp Gly 
    210                 215                 220                 


Lys Leu Phe Pro Ser Asp Gly Phe Arg Asp Cys Lys Lys Gly Asp Pro 
225                 230                 235                 240 


Lys His Gly Lys Arg Lys Arg Gly Arg Pro Arg Lys Leu Ser Lys Glu 
                245                 250                 255     


Tyr Trp Asp Cys Leu Glu Gly Lys Lys Ser Lys His Ala Pro Arg Gly 
            260                 265                 270         


Thr His Leu Trp Glu Phe Ile Arg Asp Ile Leu Ile His Pro Glu Leu 
        275                 280                 285             


Asn Glu Gly Leu Met Lys Trp Glu Asn Arg His Glu Gly Val Phe Lys 
    290                 295                 300                 


Phe Leu Arg Ser Glu Ala Val Ala Gln Leu Trp Gly Gln Lys Lys Lys 
305                 310                 315                 320 


Asn Ser Asn Met Thr Tyr Glu Lys Leu Ser Arg Ala Met Arg Tyr Tyr 
                325                 330                 335     


Tyr Lys Arg Glu Ile Leu Glu Arg Val Asp Gly Arg Arg Leu Val Tyr 
            340                 345                 350         


Lys Phe Gly Lys Asn Ser Ser Gly Trp Lys Glu Glu Glu Val Leu Gln 
        355                 360                 365             


Ser Arg Asn 
    370     


<210>  4183
<211>  255
<212>  PRT
<213>  homo sapiens

<400>  4183

Met Val Leu Glu Leu Asn Ala Ser Asp Asp Arg Gly Ile Asp Ile Ile 
1               5                   10                  15      


Arg Gly Pro Ile Leu Ser Phe Ala Ser Thr Arg Thr Ile Phe Lys Lys 
            20                  25                  30          


Gly Phe Lys Leu Val Ile Leu Asp Glu Ala Asp Ala Met Thr Gln Asp 
        35                  40                  45              


Ala Gln Asn Ala Leu Arg Arg Val Ile Glu Lys Phe Thr Glu Asn Thr 
    50                  55                  60                  


Arg Phe Cys Leu Ile Cys Asn Tyr Leu Ser Lys Ile Ile Pro Ala Leu 
65                  70                  75                  80  


Gln Ser Arg Cys Thr Arg Phe Arg Phe Gly Pro Leu Thr Pro Glu Leu 
                85                  90                  95      


Met Val Pro Arg Leu Glu His Val Val Glu Glu Glu Lys Val Asp Ile 
            100                 105                 110         


Ser Glu Asp Gly Met Lys Ala Leu Val Thr Leu Ser Ser Gly Asp Met 
        115                 120                 125             


Arg Arg Ala Leu Asn Ile Leu Gln Ser Thr Asn Met Ala Phe Gly Lys 
    130                 135                 140                 


Val Thr Glu Glu Thr Val Tyr Thr Cys Thr Gly His Pro Leu Lys Ser 
145                 150                 155                 160 


Asp Ile Ala Asn Ile Leu Asp Trp Met Leu Asn Gln Asp Phe Thr Thr 
                165                 170                 175     


Ala Tyr Arg Asn Ile Thr Glu Leu Lys Thr Leu Lys Gly Leu Ala Leu 
            180                 185                 190         


His Asp Ile Leu Thr Glu Ile His Leu Phe Val His Arg Val Asp Phe 
        195                 200                 205             


Pro Ser Ser Val Arg Ile His Leu Leu Thr Lys Met Ala Asp Ile Glu 
    210                 215                 220                 


Tyr Arg Leu Ser Val Gly Thr Asn Glu Lys Ile Gln Leu Ser Ser Leu 
225                 230                 235                 240 


Ile Ala Ala Phe Gln Val Thr Arg Asp Leu Ile Val Ala Glu Ala 
                245                 250                 255 


<210>  4184
<211>  341
<212>  PRT
<213>  homo sapiens

<400>  4184

Met Thr Met Glu Ser Gly Ala Glu Asn Gln Gln Ser Gly Asp Ala Ala 
1               5                   10                  15      


Val Thr Glu Ala Glu Asn Gln Gln Met Thr Val Gln Ala Gln Pro Gln 
            20                  25                  30          


Ile Ala Thr Leu Ala Gln Val Ser Met Pro Ala Ala His Ala Thr Ser 
        35                  40                  45              


Ser Ala Pro Thr Val Thr Leu Val Gln Leu Pro Asn Gly Gln Thr Val 
    50                  55                  60                  


Gln Val His Gly Val Ile Gln Ala Ala Gln Pro Ser Val Ile Gln Ser 
65                  70                  75                  80  


Pro Gln Val Gln Thr Val Gln Ser Ser Cys Lys Asp Leu Lys Arg Leu 
                85                  90                  95      


Phe Ser Gly Thr Gln Ile Ser Thr Ile Ala Glu Ser Glu Asp Ser Gln 
            100                 105                 110         


Glu Ser Val Asp Ser Val Thr Asp Ser Gln Lys Arg Arg Glu Ile Leu 
        115                 120                 125             


Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Asp Leu Ser Ser Asp 
    130                 135                 140                 


Ala Pro Gly Val Pro Arg Ile Glu Glu Glu Lys Ser Glu Glu Glu Thr 
145                 150                 155                 160 


Ser Ala Pro Ala Ile Thr Thr Val Thr Val Pro Thr Pro Ile Tyr Gln 
                165                 170                 175     


Thr Ser Ser Gly Gln Tyr Ile Ala Ile Thr Gln Gly Gly Ala Ile Gln 
            180                 185                 190         


Leu Ala Asn Asn Gly Thr Asp Gly Val Gln Gly Leu Gln Thr Leu Thr 
        195                 200                 205             


Met Thr Asn Ala Ala Ala Thr Gln Pro Gly Thr Thr Ile Leu Gln Tyr 
    210                 215                 220                 


Ala Gln Thr Thr Asp Gly Gln Gln Ile Leu Val Pro Ser Asn Gln Val 
225                 230                 235                 240 


Val Val Gln Ala Ala Ser Gly Asp Val Gln Thr Tyr Gln Ile Arg Thr 
                245                 250                 255     


Ala Pro Thr Ser Thr Ile Ala Pro Gly Val Val Met Ala Ser Ser Pro 
            260                 265                 270         


Ala Leu Pro Thr Gln Pro Ala Glu Glu Ala Ala Arg Lys Arg Glu Val 
        275                 280                 285             


Arg Leu Met Lys Asn Arg Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys 
    290                 295                 300                 


Lys Glu Tyr Val Lys Cys Leu Glu Asn Arg Val Ala Val Leu Glu Asn 
305                 310                 315                 320 


Gln Asn Lys Thr Leu Ile Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr 
                325                 330                 335     


Cys His Lys Ser Asp 
            340     


<210>  4185
<211>  313
<212>  PRT
<213>  homo sapiens

<400>  4185

Met Ile Gly Gln Lys Thr Leu Tyr Ser Phe Phe Ser Pro Ser Pro Ala 
1               5                   10                  15      


Arg Lys Arg His Ala Pro Ser Pro Glu Pro Ala Val Gln Gly Thr Gly 
            20                  25                  30          


Val Ala Gly Val Pro Glu Glu Ser Gly Asp Ala Ala Ala Ile Pro Ala 
        35                  40                  45              


Lys Lys Ala Pro Ala Gly Gln Glu Glu Pro Gly Thr Pro Pro Ser Ser 
    50                  55                  60                  


Pro Leu Ser Ala Glu Gln Leu Asp Arg Ile Gln Arg Asn Lys Ala Ala 
65                  70                  75                  80  


Ala Leu Leu Arg Leu Ala Ala Arg Asn Val Pro Val Gly Phe Gly Glu 
                85                  90                  95      


Ser Trp Lys Lys His Leu Ser Gly Glu Phe Gly Lys Pro Tyr Phe Ile 
            100                 105                 110         


Lys Leu Met Gly Phe Val Ala Glu Glu Arg Lys His Tyr Thr Val Tyr 
        115                 120                 125             


Pro Pro Pro His Gln Val Phe Thr Trp Thr Gln Met Cys Asp Ile Lys 
    130                 135                 140                 


Asp Val Lys Val Val Ile Leu Gly Gln Asp Pro Tyr His Gly Pro Asn 
145                 150                 155                 160 


Gln Ala His Gly Leu Cys Phe Ser Val Gln Arg Pro Val Pro Pro Pro 
                165                 170                 175     


Pro Ser Leu Glu Asn Ile Tyr Lys Glu Leu Ser Thr Asp Ile Glu Asp 
            180                 185                 190         


Phe Val His Pro Gly His Gly Asp Leu Ser Gly Trp Ala Lys Gln Gly 
        195                 200                 205             


Val Leu Leu Leu Asn Ala Val Leu Thr Val Arg Ala His Gln Ala Asn 
    210                 215                 220                 


Ser His Lys Glu Arg Gly Trp Glu Gln Phe Thr Asp Ala Val Val Ser 
225                 230                 235                 240 


Trp Leu Asn Gln Asn Ser Asn Gly Leu Val Phe Leu Leu Trp Gly Ser 
                245                 250                 255     


Tyr Ala Gln Lys Lys Gly Ser Ala Ile Asp Arg Lys Arg His His Val 
            260                 265                 270         


Leu Gln Thr Ala His Pro Ser Pro Leu Ser Val Tyr Arg Gly Phe Phe 
        275                 280                 285             


Gly Cys Arg His Phe Ser Lys Thr Asn Glu Leu Leu Gln Lys Ser Gly 
    290                 295                 300                 


Lys Lys Pro Ile Asp Trp Lys Glu Leu 
305                 310             


<210>  4186
<211>  305
<212>  PRT
<213>  homo sapiens

<400>  4186

Met Ser Ala Leu Leu Arg Leu Leu Arg Thr Gly Ala Pro Ala Ala Ala 
1               5                   10                  15      


Cys Leu Arg Leu Gly Thr Ser Ala Gly Thr Gly Ser Arg Arg Ala Met 
            20                  25                  30          


Ala Leu Tyr His Thr Glu Glu Arg Gly Gln Pro Cys Ser Gln Asn Tyr 
        35                  40                  45              


Arg Leu Phe Phe Lys Asn Val Thr Gly His Tyr Ile Ser Pro Phe His 
    50                  55                  60                  


Asp Ile Pro Leu Lys Val Asn Ser Lys Glu Glu Asn Gly Ile Pro Met 
65                  70                  75                  80  


Lys Lys Ala Arg Asn Asp Glu Tyr Glu Asn Leu Phe Asn Met Ile Val 
                85                  90                  95      


Glu Ile Pro Arg Trp Thr Asn Ala Lys Met Glu Ile Ala Thr Lys Glu 
            100                 105                 110         


Pro Met Asn Pro Ile Lys Gln Tyr Val Lys Asp Gly Lys Leu Arg Tyr 
        115                 120                 125             


Val Ala Asn Ile Phe Pro Tyr Lys Gly Tyr Ile Trp Asn Tyr Gly Thr 
    130                 135                 140                 


Leu Pro Gln Ile Leu Ser Cys Gly Glu Val Ile His Val Lys Ile Leu 
145                 150                 155                 160 


Gly Ile Leu Ala Leu Ile Asp Glu Gly Glu Thr Asp Trp Lys Leu Ile 
                165                 170                 175     


Ala Ile Asn Ala Asn Asp Pro Glu Ala Ser Lys Phe His Asp Ile Asp 
            180                 185                 190         


Asp Val Lys Lys Phe Lys Pro Gly Tyr Leu Glu Ala Thr Leu Asn Trp 
        195                 200                 205             


Phe Arg Leu Tyr Lys Val Pro Asp Gly Lys Pro Glu Asn Gln Phe Ala 
    210                 215                 220                 


Phe Asn Gly Glu Phe Lys Asn Lys Ala Phe Ala Leu Glu Val Ile Lys 
225                 230                 235                 240 


Ser Thr His Gln Cys Trp Lys Ala Leu Leu Met Lys Lys Cys Asn Gly 
                245                 250                 255     


Gly Ala Ile Asn Cys Thr Asn Val Gln Ile Ser Asp Ser Pro Phe Arg 
            260                 265                 270         


Cys Thr Gln Glu Glu Ala Arg Ser Leu Val Glu Ser Val Ser Ser Ser 
        275                 280                 285             


Pro Asn Lys Glu Ser Asn Glu Glu Glu Gln Val Trp His Phe Leu Gly 
    290                 295                 300                 


Lys 
305 


<210>  4187
<211>  564
<212>  PRT
<213>  homo sapiens

<400>  4187

Met Ala Gly Thr Val Arg Thr Ala Cys Leu Val Val Ala Met Leu Leu 
1               5                   10                  15      


Ser Leu Asp Phe Pro Gly Gln Ala Gln Pro Pro Pro Pro Pro Pro Asp 
            20                  25                  30          


Ala Thr Cys His Gln Val Arg Ser Phe Phe Gln Arg Leu Gln Pro Gly 
        35                  40                  45              


Leu Lys Trp Val Pro Glu Thr Pro Val Pro Gly Ser Asp Leu Gln Val 
    50                  55                  60                  


Cys Leu Pro Lys Gly Pro Thr Cys Cys Ser Arg Lys Met Glu Glu Lys 
65                  70                  75                  80  


Tyr Gln Leu Thr Ala Arg Leu Asn Met Glu Gln Leu Leu Gln Ser Ala 
                85                  90                  95      


Lys Ala Phe Glu Ile Val Val Arg His Ala Lys Asn Tyr Thr Asn Ala 
            100                 105                 110         


Met Phe Lys Asn Asn Tyr Pro Ser Leu Thr Pro Gln Ala Phe Glu Phe 
        115                 120                 125             


Val Gly Glu Phe Phe Thr Asp Val Ser Leu Tyr Ile Leu Gly Ser Asp 
    130                 135                 140                 


Ile Asn Val Asp Asp Met Val Asn Glu Leu Phe Asp Ser Leu Phe Pro 
145                 150                 155                 160 


Val Ile Tyr Thr Gln Leu Met Asn Pro Gly Leu Pro Asp Ser Ala Leu 
                165                 170                 175     


Asp Ile Asn Glu Cys Leu Arg Gly Ala Arg Arg Asp Leu Lys Val Phe 
            180                 185                 190         


Gly Asn Phe Pro Lys Leu Ile Met Thr Gln Val Ser Lys Ser Leu Gln 
        195                 200                 205             


Val Thr Arg Ile Phe Leu Gln Ala Leu Asn Leu Gly Ile Glu Val Ile 
    210                 215                 220                 


Asn Thr Thr Asp His Leu Lys Phe Ser Lys Asp Cys Gly Arg Met Leu 
225                 230                 235                 240 


Thr Arg Met Trp Tyr Cys Ser Tyr Cys Gln Gly Leu Met Met Val Lys 
                245                 250                 255     


Pro Cys Gly Gly Tyr Cys Asn Val Val Met Gln Gly Cys Met Ala Gly 
            260                 265                 270         


Val Val Glu Ile Asp Lys Tyr Trp Arg Glu Tyr Ile Leu Ser Leu Glu 
        275                 280                 285             


Glu Leu Val Asn Gly Met Tyr Arg Ile Tyr Asp Met Glu Asn Val Leu 
    290                 295                 300                 


Leu Gly Leu Phe Ser Thr Ile His Asp Ser Ile Gln Tyr Val Gln Lys 
305                 310                 315                 320 


Asn Ala Gly Lys Leu Thr Thr Thr Ile Gly Lys Leu Cys Ala His Ser 
                325                 330                 335     


Gln Gln Arg Gln Tyr Arg Ser Ala Tyr Tyr Pro Glu Asp Leu Phe Ile 
            340                 345                 350         


Asp Lys Lys Val Leu Lys Val Ala His Val Glu His Glu Glu Thr Leu 
        355                 360                 365             


Ser Ser Arg Arg Arg Glu Leu Ile Gln Lys Leu Lys Ser Phe Ile Ser 
    370                 375                 380                 


Phe Tyr Ser Ala Leu Pro Gly Tyr Ile Cys Ser His Ser Pro Val Ala 
385                 390                 395                 400 


Glu Asn Asp Thr Leu Cys Trp Asn Gly Gln Glu Leu Val Glu Arg Tyr 
                405                 410                 415     


Ser Gln Lys Ala Ala Arg Asn Gly Met Lys Asn Gln Phe Asn Leu His 
            420                 425                 430         


Glu Leu Lys Met Lys Gly Pro Glu Pro Val Val Ser Gln Ile Ile Asp 
        435                 440                 445             


Lys Leu Lys His Ile Asn Gln Leu Leu Arg Thr Met Ser Met Pro Lys 
    450                 455                 460                 


Gly Arg Val Leu Asp Lys Asn Leu Asp Glu Glu Gly Phe Glu Ser Gly 
465                 470                 475                 480 


Asp Cys Gly Asp Asp Glu Asp Glu Cys Ile Gly Gly Ser Gly Asp Gly 
                485                 490                 495     


Met Ile Lys Val Lys Asn Gln Leu Arg Phe Leu Ala Glu Leu Ala Tyr 
            500                 505                 510         


Asp Leu Asp Val Asp Asp Ala Pro Gly Asn Ser Gln Gln Ala Thr Pro 
        515                 520                 525             


Lys Asp Asn Glu Ile Ser Thr Phe His Asn Leu Gly Asn Val His Ser 
    530                 535                 540                 


Pro Leu Lys Leu Leu Thr Ser Met Ala Ile Ser Val Val Cys Phe Phe 
545                 550                 555                 560 


Phe Leu Val His 
                


<210>  4188
<211>  190
<212>  PRT
<213>  homo sapiens

<400>  4188

Met Ser Thr Arg Lys Arg Arg Gly Gly Ala Ile Asn Ser Arg Gln Ala 
1               5                   10                  15      


Gln Lys Arg Thr Arg Glu Ala Thr Ser Thr Pro Glu Ile Ser Leu Glu 
            20                  25                  30          


Ala Glu Pro Ile Glu Leu Val Glu Thr Ala Gly Asp Glu Ile Val Asp 
        35                  40                  45              


Leu Thr Cys Glu Ser Leu Glu Pro Val Val Val Asp Leu Thr His Asn 
    50                  55                  60                  


Asp Ser Val Val Ile Val Asp Glu Arg Arg Arg Pro Arg Arg Asn Ala 
65                  70                  75                  80  


Arg Arg Leu Pro Gln Asp His Ala Asp Ser Cys Val Val Ser Ser Asp 
                85                  90                  95      


Asp Glu Glu Leu Ser Arg Asp Arg Asp Val Tyr Val Thr Thr His Thr 
            100                 105                 110         


Pro Arg Asn Ala Arg Asp Glu Gly Ala Thr Gly Leu Arg Pro Ser Gly 
        115                 120                 125             


Thr Val Ser Cys Pro Ile Cys Met Asp Gly Tyr Ser Glu Ile Val Gln 
    130                 135                 140                 


Asn Gly Arg Leu Ile Val Ser Thr Glu Cys Gly His Val Phe Cys Ser 
145                 150                 155                 160 


Gln Cys Leu Arg Asp Ser Leu Lys Asn Ala Asn Thr Cys Pro Thr Cys 
                165                 170                 175     


Arg Lys Lys Ile Asn His Lys Arg Tyr His Pro Ile Tyr Ile 
            180                 185                 190 


<210>  4189
<211>  503
<212>  PRT
<213>  homo sapiens

<400>  4189

Met Pro Val Pro Pro Pro Pro Ala Pro Pro Pro Pro Pro Thr Phe Ala 
1               5                   10                  15      


Leu Ala Asn Thr Glu Lys Pro Thr Leu Asn Lys Thr Glu Gln Ala Gly 
            20                  25                  30          


Arg Asn Ala Leu Leu Ser Asp Ile Ser Lys Gly Lys Lys Leu Lys Lys 
        35                  40                  45              


Thr Val Thr Asn Asp Arg Ser Ala Pro Ile Leu Asp Lys Pro Lys Gly 
    50                  55                  60                  


Ala Gly Ala Gly Gly Gly Gly Gly Gly Phe Gly Gly Gly Gly Gly Phe 
65                  70                  75                  80  


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ser Phe Gly Gly Gly Gly 
                85                  90                  95      


Pro Pro Gly Leu Gly Gly Leu Phe Gln Ala Gly Met Pro Lys Leu Arg 
            100                 105                 110         


Ser Thr Ala Asn Arg Asp Asn Asp Ser Gly Gly Ser Arg Pro Pro Leu 
        115                 120                 125             


Leu Pro Pro Gly Gly Arg Ser Thr Ser Ala Lys Pro Phe Ser Pro Pro 
    130                 135                 140                 


Ser Gly Pro Gly Arg Phe Pro Val Pro Ser Pro Gly His Arg Ser Gly 
145                 150                 155                 160 


Pro Pro Glu Pro Gln Arg Asn Arg Met Pro Pro Pro Arg Pro Asp Val 
                165                 170                 175     


Gly Ser Lys Pro Asp Ser Ile Pro Pro Pro Val Pro Ser Thr Pro Arg 
            180                 185                 190         


Pro Ile Gln Ser Ser Pro His Asn Arg Gly Ser Pro Pro Val Pro Gly 
        195                 200                 205             


Gly Pro Arg Gln Pro Ser Pro Gly Pro Thr Pro Pro Pro Phe Pro Gly 
    210                 215                 220                 


Asn Arg Gly Thr Ala Leu Gly Gly Gly Ser Ile Arg Gln Ser Pro Leu 
225                 230                 235                 240 


Ser Ser Ser Ser Pro Phe Ser Asn Arg Pro Pro Leu Pro Pro Thr Pro 
                245                 250                 255     


Ser Arg Ala Leu Asp Asp Lys Pro Pro Pro Pro Pro Pro Pro Val Gly 
            260                 265                 270         


Asn Arg Pro Ser Ile His Arg Glu Ala Val Pro Pro Pro Pro Pro Gln 
        275                 280                 285             


Asn Asn Lys Pro Pro Val Pro Ser Thr Pro Arg Pro Ser Ala Ser Ser 
    290                 295                 300                 


Gln Ala Pro Pro Pro Pro Pro Pro Pro Ser Arg Pro Gly Pro Pro Pro 
305                 310                 315                 320 


Leu Pro Pro Ser Ser Ser Gly Asn Asp Glu Thr Pro Arg Leu Pro Gln 
                325                 330                 335     


Arg Asn Leu Ser Leu Ser Ser Ser Thr Pro Pro Leu Pro Ser Pro Gly 
            340                 345                 350         


Arg Ser Gly Pro Leu Pro Pro Pro Pro Ser Glu Arg Pro Pro Pro Pro 
        355                 360                 365             


Val Arg Asp Pro Pro Gly Arg Ser Gly Pro Leu Pro Pro Pro Pro Pro 
    370                 375                 380                 


Val Ser Arg Asn Gly Ser Thr Ser Arg Ala Leu Pro Ala Thr Pro Gln 
385                 390                 395                 400 


Leu Pro Ser Arg Ser Gly Val Asp Ser Pro Arg Ser Gly Pro Arg Pro 
                405                 410                 415     


Pro Leu Pro Pro Asp Arg Pro Ser Ala Gly Ala Pro Pro Pro Pro Pro 
            420                 425                 430         


Pro Ser Thr Ser Ile Arg Asn Gly Phe Gln Asp Ser Pro Cys Glu Asp 
        435                 440                 445             


Glu Trp Glu Ser Arg Phe Tyr Phe His Pro Ile Ser Asp Leu Pro Pro 
    450                 455                 460                 


Pro Glu Pro Tyr Val Gln Thr Thr Lys Ser Tyr Pro Ser Lys Leu Ala 
465                 470                 475                 480 


Arg Asn Glu Ser Arg Ser Gly Ser Asn Arg Arg Glu Arg Gly Ala Pro 
                485                 490                 495     


Pro Leu Pro Pro Ile Pro Arg 
            500             


<210>  4190
<211>  359
<212>  PRT
<213>  homo sapiens

<400>  4190

Met Pro Ser Leu Leu Leu Leu Phe Thr Ala Ala Leu Leu Ser Ser Trp 
1               5                   10                  15      


Ala Gln Leu Leu Thr Asp Ala Asn Ser Trp Trp Ser Leu Ala Leu Asn 
            20                  25                  30          


Pro Val Gln Arg Pro Glu Met Phe Ile Ile Gly Ala Gln Pro Val Cys 
        35                  40                  45              


Ser Gln Leu Pro Gly Leu Ser Pro Gly Gln Arg Lys Leu Cys Gln Leu 
    50                  55                  60                  


Tyr Gln Glu His Met Ala Tyr Ile Gly Glu Gly Ala Lys Thr Gly Ile 
65                  70                  75                  80  


Lys Glu Cys Gln His Gln Phe Arg Gln Arg Arg Trp Asn Cys Ser Thr 
                85                  90                  95      


Ala Asp Asn Ala Ser Val Phe Gly Arg Val Met Gln Ile Gly Ser Arg 
            100                 105                 110         


Glu Thr Ala Phe Thr His Ala Val Ser Ala Ala Gly Val Val Asn Ala 
        115                 120                 125             


Ile Ser Arg Ala Cys Arg Glu Gly Glu Leu Ser Thr Cys Gly Cys Ser 
    130                 135                 140                 


Arg Thr Ala Arg Pro Lys Asp Leu Pro Arg Asp Trp Leu Trp Gly Gly 
145                 150                 155                 160 


Cys Gly Asp Asn Val Glu Tyr Gly Tyr Arg Phe Ala Lys Glu Phe Val 
                165                 170                 175     


Asp Ala Arg Glu Arg Glu Lys Asn Phe Ala Lys Gly Ser Glu Glu Gln 
            180                 185                 190         


Gly Arg Val Leu Met Asn Leu Gln Asn Asn Glu Ala Gly Arg Arg Ala 
        195                 200                 205             


Val Tyr Lys Met Ala Asp Val Ala Cys Lys Cys His Gly Val Ser Gly 
    210                 215                 220                 


Ser Cys Ser Leu Lys Thr Cys Trp Leu Gln Leu Ala Glu Phe Arg Lys 
225                 230                 235                 240 


Val Gly Asp Arg Leu Lys Glu Lys Tyr Asp Ser Ala Ala Ala Met Arg 
                245                 250                 255     


Val Thr Arg Lys Gly Arg Leu Glu Leu Val Asn Ser Arg Phe Thr Gln 
            260                 265                 270         


Pro Thr Pro Glu Asp Leu Val Tyr Val Asp Pro Ser Pro Asp Tyr Cys 
        275                 280                 285             


Leu Arg Asn Glu Ser Thr Gly Ser Leu Gly Thr Gln Gly Arg Leu Cys 
    290                 295                 300                 


Asn Lys Thr Ser Glu Gly Met Asp Gly Cys Glu Leu Met Cys Cys Gly 
305                 310                 315                 320 


Arg Gly Tyr Asn Gln Phe Lys Ser Val Gln Val Glu Arg Cys His Cys 
                325                 330                 335     


Lys Phe His Trp Cys Cys Phe Val Arg Cys Lys Lys Cys Thr Glu Ile 
            340                 345                 350         


Val Asp Gln Tyr Ile Cys Lys 
        355                 


<210>  4191
<211>  1515
<212>  PRT
<213>  homo sapiens

<400>  4191

Met Glu Pro Arg Ser Met Glu Tyr Phe Cys Ala Gln Val Gln Gln Lys 
1               5                   10                  15      


Asp Val Gly Gly Arg Leu Gln Val Gly Gln Glu Leu Leu Leu Tyr Leu 
            20                  25                  30          


Gly Ala Pro Gly Ala Ile Ser Asp Leu Glu Glu Asp Leu Gly Arg Leu 
        35                  40                  45              


Gly Lys Thr Val Asp Ala Leu Thr Gly Trp Val Gly Ser Ser Asn Tyr 
    50                  55                  60                  


Arg Val Ser Leu Met Gly Leu Glu Ile Leu Ser Ala Phe Val Asp Arg 
65                  70                  75                  80  


Leu Ser Thr Arg Phe Lys Ser Tyr Val Ala Met Val Ile Val Ala Leu 
                85                  90                  95      


Ile Asp Arg Met Gly Asp Ala Lys Asp Lys Val Arg Asp Glu Ala Gln 
            100                 105                 110         


Thr Leu Ile Leu Lys Leu Met Asp Gln Val Ala Pro Pro Met Tyr Ile 
        115                 120                 125             


Trp Glu Gln Leu Ala Ser Gly Phe Lys His Lys Asn Phe Arg Ser Arg 
    130                 135                 140                 


Glu Gly Val Cys Leu Cys Leu Ile Glu Thr Leu Asn Ile Phe Gly Ala 
145                 150                 155                 160 


Gln Pro Leu Val Ile Ser Lys Leu Ile Pro His Leu Cys Ile Leu Phe 
                165                 170                 175     


Gly Asp Ser Asn Ser Gln Val Arg Asp Ala Ala Ile Leu Ala Ile Val 
            180                 185                 190         


Glu Ile Tyr Arg His Val Gly Glu Lys Val Arg Met Asp Leu Tyr Lys 
        195                 200                 205             


Arg Gly Ile Pro Pro Ala Arg Leu Glu Met Ile Phe Ala Lys Phe Asp 
    210                 215                 220                 


Glu Val Gln Ser Ser Gly Gly Met Ile Leu Ser Val Cys Lys Asp Lys 
225                 230                 235                 240 


Ser Phe Asp Asp Glu Glu Ser Val Asp Gly Asn Arg Pro Ser Ser Ala 
                245                 250                 255     


Ala Ser Ala Phe Lys Val Pro Ala Pro Lys Thr Ser Gly Asn Pro Ala 
            260                 265                 270         


Asn Ser Ala Arg Lys Pro Gly Ser Ala Gly Gly Pro Lys Val Gly Ala 
        275                 280                 285             


Gly Ala Ser Lys Glu Gly Gly Ala Gly Ala Val Asp Glu Asp Asp Phe 
    290                 295                 300                 


Ile Lys Ala Phe Thr Asp Val Pro Ser Ile Gln Ile Tyr Ser Ser Arg 
305                 310                 315                 320 


Glu Leu Glu Glu Thr Leu Asn Lys Ile Arg Glu Ile Leu Ser Asp Asp 
                325                 330                 335     


Lys His Asp Trp Asp Gln Arg Ala Asn Ala Leu Lys Lys Ile Arg Ser 
            340                 345                 350         


Leu Leu Val Ala Gly Ala Ala Gln Tyr Asp Cys Phe Phe Gln His Leu 
        355                 360                 365             


Arg Leu Leu Asp Gly Ala Leu Lys Leu Ser Ala Lys Asp Leu Arg Ser 
    370                 375                 380                 


Gln Val Val Arg Glu Ala Cys Ile Thr Val Ala His Leu Ser Thr Val 
385                 390                 395                 400 


Leu Gly Asn Lys Phe Asp His Gly Ala Glu Ala Ile Val Pro Thr Leu 
                405                 410                 415     


Phe Asn Leu Val Pro Asn Ser Ala Lys Val Met Ala Thr Ser Gly Cys 
            420                 425                 430         


Ala Ala Ile Arg Phe Ile Ile Arg His Thr His Val Pro Arg Leu Ile 
        435                 440                 445             


Pro Leu Ile Thr Ser Asn Cys Thr Ser Lys Ser Val Pro Val Arg Arg 
    450                 455                 460                 


Arg Ser Phe Glu Phe Leu Asp Leu Leu Leu Gln Glu Trp Gln Thr His 
465                 470                 475                 480 


Ser Leu Glu Arg His Ala Ala Val Leu Val Glu Thr Ile Lys Lys Gly 
                485                 490                 495     


Ile His Asp Ala Asp Ala Glu Ala Arg Val Glu Ala Arg Lys Thr Tyr 
            500                 505                 510         


Met Gly Leu Arg Asn His Phe Pro Gly Glu Ala Glu Thr Leu Tyr Asn 
        515                 520                 525             


Ser Leu Glu Pro Ser Tyr Gln Lys Ser Leu Gln Thr Tyr Leu Lys Ser 
    530                 535                 540                 


Ser Gly Ser Val Ala Ser Leu Pro Gln Ser Asp Arg Ser Ser Ser Ser 
545                 550                 555                 560 


Ser Gln Glu Ser Leu Asn Arg Pro Phe Ser Ser Lys Trp Ser Thr Ala 
                565                 570                 575     


Asn Pro Ser Thr Val Ala Gly Arg Val Ser Ala Gly Ser Ser Lys Ala 
            580                 585                 590         


Ser Ser Leu Pro Gly Ser Leu Gln Arg Ser Arg Ser Asp Ile Asp Val 
        595                 600                 605             


Asn Ala Ala Ala Gly Ala Lys Ala His His Ala Ala Gly Gln Ser Val 
    610                 615                 620                 


Arg Ser Gly Arg Leu Gly Ala Gly Ala Leu Asn Ala Gly Ser Tyr Ala 
625                 630                 635                 640 


Ser Leu Glu Asp Thr Ser Asp Lys Leu Asp Gly Thr Ala Ser Glu Asp 
                645                 650                 655     


Gly Arg Val Arg Ala Lys Leu Ser Ala Pro Leu Ala Gly Met Gly Asn 
            660                 665                 670         


Ala Lys Ala Asp Ser Arg Gly Arg Ser Arg Thr Lys Met Val Ser Gln 
        675                 680                 685             


Ser Gln Pro Gly Ser Arg Ser Gly Ser Pro Gly Arg Val Leu Thr Thr 
    690                 695                 700                 


Thr Ala Leu Ser Thr Val Ser Ser Gly Val Gln Arg Val Leu Val Asn 
705                 710                 715                 720 


Ser Ala Ser Ala Gln Lys Arg Ser Lys Ile Pro Arg Ser Gln Gly Cys 
                725                 730                 735     


Ser Arg Glu Ala Ser Pro Ser Arg Leu Ser Val Ala Arg Ser Ser Arg 
            740                 745                 750         


Ile Pro Arg Pro Ser Val Ser Gln Gly Cys Ser Arg Glu Ala Ser Arg 
        755                 760                 765             


Glu Ser Ser Arg Asp Thr Ser Pro Val Arg Ser Phe Gln Pro Leu Gly 
    770                 775                 780                 


Pro Gly Tyr Gly Ile Ser Gln Ser Ser Arg Leu Ser Ser Ser Val Ser 
785                 790                 795                 800 


Ala Met Arg Val Leu Asn Thr Gly Ser Asp Val Glu Glu Ala Val Ala 
                805                 810                 815     


Asp Ala Leu Leu Leu Gly Asp Ile Arg Thr Lys Lys Lys Pro Ala Arg 
            820                 825                 830         


Arg Arg Tyr Glu Ser Tyr Gly Met His Ser Asp Asp Asp Ala Asn Ser 
        835                 840                 845             


Asp Ala Ser Ser Ala Cys Ser Glu Arg Ser Tyr Ser Ser Arg Asn Gly 
    850                 855                 860                 


Ser Ile Pro Thr Tyr Met Arg Gln Thr Glu Asp Val Ala Glu Val Leu 
865                 870                 875                 880 


Asn Arg Cys Ala Ser Ser Asn Trp Ser Glu Arg Lys Glu Gly Leu Leu 
                885                 890                 895     


Gly Leu Gln Asn Leu Leu Lys Asn Gln Arg Thr Leu Ser Arg Val Glu 
            900                 905                 910         


Leu Lys Arg Leu Cys Glu Ile Phe Thr Arg Met Phe Ala Asp Pro His 
        915                 920                 925             


Gly Lys Arg Val Phe Ser Met Phe Leu Glu Thr Leu Val Asp Phe Ile 
    930                 935                 940                 


Gln Val His Lys Asp Asp Leu Gln Asp Trp Leu Phe Val Leu Leu Thr 
945                 950                 955                 960 


Gln Leu Leu Lys Lys Met Gly Ala Asp Leu Leu Gly Ser Val Gln Ala 
                965                 970                 975     


Lys Val Gln Lys Ala Leu Asp Val Thr Arg Glu Ser Phe Pro Asn Asp 
            980                 985                 990         


Leu Gln Phe Asn Ile Leu Met Arg  Phe Thr Val Asp Gln  Thr Gln Thr 
        995                 1000                 1005             


Pro Ser  Leu Lys Val Lys Val  Ala Ile Leu Lys Tyr  Ile Glu Thr 
    1010                 1015                 1020             


Leu Ala  Lys Gln Met Asp Pro  Gly Asp Phe Ile Asn  Ser Ser Glu 
    1025                 1030                 1035             


Thr Arg  Leu Ala Val Ser Arg  Val Ile Thr Trp Thr  Thr Glu Pro 
    1040                 1045                 1050             


Lys Ser  Ser Asp Val Arg Lys  Ala Ala Gln Ser Val  Leu Ile Ser 
    1055                 1060                 1065             


Leu Phe  Glu Leu Asn Thr Pro  Glu Phe Thr Met Leu  Leu Gly Ala 
    1070                 1075                 1080             


Leu Pro  Lys Thr Phe Gln Asp  Gly Ala Thr Lys Leu  Leu His Asn 
    1085                 1090                 1095             


His Leu  Arg Asn Thr Gly Asn  Gly Thr Gln Ser Ser  Met Gly Ser 
    1100                 1105                 1110             


Pro Leu  Thr Arg Pro Thr Pro  Arg Ser Pro Ala Asn  Trp Ser Ser 
    1115                 1120                 1125             


Pro Leu  Thr Ser Pro Thr Asn  Thr Ser Gln Asn Thr  Leu Ser Pro 
    1130                 1135                 1140             


Ser Ala  Phe Asp Tyr Asp Thr  Glu Asn Met Asn Ser  Glu Asp Ile 
    1145                 1150                 1155             


Tyr Ser  Ser Leu Arg Gly Val  Thr Glu Ala Ile Gln  Asn Phe Ser 
    1160                 1165                 1170             


Phe Arg  Ser Gln Glu Asp Met  Asn Glu Pro Leu Lys  Arg Asp Ser 
    1175                 1180                 1185             


Lys Lys  Asp Asp Gly Asp Ser  Met Cys Gly Gly Pro  Gly Met Ser 
    1190                 1195                 1200             


Asp Pro  Arg Ala Gly Gly Asp  Ala Thr Asp Ser Ser  Gln Thr Ala 
    1205                 1210                 1215             


Leu Asp  Asn Lys Ala Ser Leu  Leu His Ser Met Pro  Thr His Ser 
    1220                 1225                 1230             


Ser Pro  Arg Ser Arg Asp Tyr  Asn Pro Tyr Asn Tyr  Ser Asp Ser 
    1235                 1240                 1245             


Ile Ser  Pro Phe Asn Lys Ser  Ala Leu Lys Glu Ala  Met Phe Asp 
    1250                 1255                 1260             


Asp Asp  Ala Asp Gln Phe Pro  Asp Asp Leu Ser Leu  Asp His Ser 
    1265                 1270                 1275             


Asp Leu  Val Ala Glu Leu Leu  Lys Glu Leu Ser Asn  His Asn Glu 
    1280                 1285                 1290             


Arg Val  Glu Glu Arg Lys Ile  Ala Leu Tyr Glu Leu  Met Lys Leu 
    1295                 1300                 1305             


Thr Gln  Glu Glu Ser Phe Ser  Val Trp Asp Glu His  Phe Lys Thr 
    1310                 1315                 1320             


Ile Leu  Leu Leu Leu Leu Glu  Thr Leu Gly Asp Lys  Glu Pro Thr 
    1325                 1330                 1335             


Ile Arg  Ala Leu Ala Leu Lys  Val Leu Arg Glu Ile  Leu Arg His 
    1340                 1345                 1350             


Gln Pro  Ala Arg Phe Lys Asn  Tyr Ala Glu Leu Thr  Val Met Lys 
    1355                 1360                 1365             


Thr Leu  Glu Ala His Lys Asp  Pro His Lys Glu Val  Val Arg Ser 
    1370                 1375                 1380             


Ala Glu  Glu Ala Ala Ser Val  Leu Ala Thr Ser Ile  Ser Pro Glu 
    1385                 1390                 1395             


Gln Cys  Ile Lys Val Leu Cys  Pro Ile Ile Gln Thr  Ala Asp Tyr 
    1400                 1405                 1410             


Pro Ile  Asn Leu Ala Ala Ile  Lys Met Gln Thr Lys  Val Ile Glu 
    1415                 1420                 1425             


Arg Val  Ser Lys Glu Thr Leu  Asn Leu Leu Leu Pro  Glu Ile Met 
    1430                 1435                 1440             


Pro Gly  Leu Ile Gln Gly Tyr  Asp Asn Ser Glu Ser  Ser Val Arg 
    1445                 1450                 1455             


Lys Ala  Cys Val Phe Cys Leu  Val Ala Val His Ala  Val Ile Gly 
    1460                 1465                 1470             


Asp Glu  Leu Lys Pro His Leu  Ser Gln Leu Thr Gly  Ser Lys Met 
    1475                 1480                 1485             


Lys Leu  Leu Asn Leu Tyr Ile  Lys Arg Ala Gln Thr  Gly Ser Gly 
    1490                 1495                 1500             


Gly Ala  Asp Pro Thr Thr Asp  Val Ser Gly Gln Ser  
    1505                 1510                 1515 


<210>  4192
<211>  418
<212>  PRT
<213>  homo sapiens

<400>  4192

Met Arg Thr Lys Ala Ala Gly Cys Ala Glu Arg Arg Pro Leu Gln Pro 
1               5                   10                  15      


Arg Thr Glu Ala Ala Ala Ala Pro Ala Gly Arg Ala Met Pro Ser Glu 
            20                  25                  30          


Tyr Thr Tyr Val Lys Leu Arg Ser Asp Cys Ser Arg Pro Ser Leu Gln 
        35                  40                  45              


Trp Tyr Thr Arg Ala Gln Ser Lys Met Arg Arg Pro Ser Leu Leu Leu 
    50                  55                  60                  


Lys Asp Ile Leu Lys Cys Thr Leu Leu Val Phe Gly Val Trp Ile Leu 
65                  70                  75                  80  


Tyr Ile Leu Lys Leu Asn Tyr Thr Thr Glu Glu Cys Asp Met Lys Lys 
                85                  90                  95      


Met His Tyr Val Asp Pro Asp His Val Lys Arg Ala Gln Lys Tyr Ala 
            100                 105                 110         


Gln Gln Val Leu Gln Lys Glu Cys Arg Pro Lys Phe Ala Lys Thr Ser 
        115                 120                 125             


Met Ala Leu Leu Phe Glu His Arg Tyr Ser Val Asp Leu Leu Pro Phe 
    130                 135                 140                 


Val Gln Lys Ala Pro Lys Asp Ser Glu Ala Glu Ser Lys Tyr Asp Pro 
145                 150                 155                 160 


Pro Phe Gly Phe Arg Lys Phe Ser Ser Lys Val Gln Thr Leu Leu Glu 
                165                 170                 175     


Leu Leu Pro Glu His Asp Leu Pro Glu His Leu Lys Ala Lys Thr Cys 
            180                 185                 190         


Arg Arg Cys Val Val Ile Gly Ser Gly Gly Ile Leu His Gly Leu Glu 
        195                 200                 205             


Leu Gly His Thr Leu Asn Gln Phe Asp Val Val Ile Arg Leu Asn Ser 
    210                 215                 220                 


Ala Pro Val Glu Gly Tyr Ser Glu His Val Gly Asn Lys Thr Thr Ile 
225                 230                 235                 240 


Arg Met Thr Tyr Pro Glu Gly Ala Pro Leu Ser Asp Leu Glu Tyr Tyr 
                245                 250                 255     


Ser Asn Asp Leu Phe Val Ala Val Leu Phe Lys Ser Val Asp Phe Asn 
            260                 265                 270         


Trp Leu Gln Ala Met Val Lys Lys Glu Thr Leu Pro Phe Trp Val Arg 
        275                 280                 285             


Leu Phe Phe Trp Lys Gln Val Ala Glu Lys Ile Pro Leu Gln Pro Lys 
    290                 295                 300                 


His Phe Arg Ile Leu Asn Pro Val Ile Ile Lys Glu Thr Ala Phe Asp 
305                 310                 315                 320 


Ile Leu Gln Tyr Ser Glu Pro Gln Ser Arg Phe Trp Gly Arg Asp Lys 
                325                 330                 335     


Asn Val Pro Thr Ile Gly Val Ile Ala Val Val Leu Ala Thr His Leu 
            340                 345                 350         


Cys Asp Glu Val Ser Leu Ala Gly Phe Gly Tyr Asp Leu Asn Gln Pro 
        355                 360                 365             


Arg Thr Pro Leu His Tyr Phe Asp Ser Gln Cys Met Ala Ala Met Asn 
    370                 375                 380                 


Phe Gln Thr Met His Asn Val Thr Thr Glu Thr Lys Phe Leu Leu Lys 
385                 390                 395                 400 


Leu Val Lys Glu Gly Val Val Lys Asp Leu Ser Gly Gly Ile Asp Arg 
                405                 410                 415     


Glu Phe 
        


<210>  4193
<211>  81
<212>  PRT
<213>  homo sapiens

<400>  4193

Met Asn Arg Glu Gly Ala Pro Gly Lys Ser Pro Glu Glu Met Tyr Ile 
1               5                   10                  15      


Gln Gln Lys Val Arg Val Leu Leu Met Leu Arg Lys Met Gly Ser Asn 
            20                  25                  30          


Leu Thr Ala Ser Glu Glu Glu Phe Leu Arg Thr Tyr Ala Gly Val Val 
        35                  40                  45              


Asn Ser Gln Leu Ser Gln Leu Pro Pro His Ser Ile Asp Gln Gly Ala 
    50                  55                  60                  


Glu Asp Val Val Met Ala Phe Ser Arg Ser Glu Thr Glu Asp Arg Arg 
65                  70                  75                  80  


Gln 
    


<210>  4194
<211>  168
<212>  PRT
<213>  homo sapiens

<400>  4194

Met Arg Ser Ile Arg Lys Arg Trp Thr Ile Cys Thr Ile Ser Leu Leu 
1               5                   10                  15      


Leu Ile Phe Tyr Lys Thr Lys Glu Ile Ala Arg Thr Glu Glu His Gln 
            20                  25                  30          


Glu Thr Gln Leu Ile Gly Asp Gly Glu Leu Ser Leu Ser Arg Ser Leu 
        35                  40                  45              


Val Asn Ser Ser Asp Lys Ile Ile Arg Lys Ala Gly Ser Ser Ile Phe 
    50                  55                  60                  


Gln His Asn Val Glu Gly Trp Lys Ile Asn Ser Ser Leu Val Leu Glu 
65                  70                  75                  80  


Ile Arg Lys Asn Ile Leu Arg Phe Leu Asp Ala Glu Arg Asp Val Ser 
                85                  90                  95      


Val Val Lys Ser Ser Phe Lys Pro Gly Asp Val Ile His Tyr Val Leu 
            100                 105                 110         


Asp Arg Arg Arg Thr Leu Asn Ile Ser His Asp Leu His Ser Leu Leu 
        115                 120                 125             


Pro Glu Val Ser Pro Met Lys Asn Arg Arg Phe Lys Thr Cys Ala Val 
    130                 135                 140                 


Val Gly Asn Ser Gly Ile Leu Leu Asp Ser Glu Cys Gly Lys Glu Ile 
145                 150                 155                 160 


Asp Ser His Asn Phe Val Ile Arg 
                165             


<210>  4195
<211>  1231
<212>  PRT
<213>  homo sapiens

<400>  4195

Met Ile Ala Ala Pro Glu Ile Pro Thr Asp Phe Asn Leu Leu Gln Glu 
1               5                   10                  15      


Ser Glu Thr His Phe Ser Ser Asp Thr Asp Phe Glu Asp Ile Glu Gly 
            20                  25                  30          


Lys Asn Gln Lys Gln Gly Lys Gly Lys Thr Cys Lys Lys Gly Lys Lys 
        35                  40                  45              


Gly Pro Ala Glu Lys Gly Lys Gly Gly Asn Gly Gly Gly Lys Pro Pro 
    50                  55                  60                  


Ser Gly Pro Asn Arg Met Asn Gly His His Gln Gln Asn Gly Val Glu 
65                  70                  75                  80  


Asn Met Met Leu Phe Glu Val Val Lys Met Gly Lys Ser Ala Met Gln 
                85                  90                  95      


Ser Val Val Asp Asp Trp Ile Glu Ser Tyr Lys His Asp Arg Asp Ile 
            100                 105                 110         


Ala Leu Leu Asp Leu Ile Asn Phe Phe Ile Gln Cys Ser Gly Cys Lys 
        115                 120                 125             


Gly Val Val Thr Ala Glu Met Phe Arg His Met Gln Asn Ser Glu Ile 
    130                 135                 140                 


Ile Arg Lys Met Thr Glu Glu Phe Asp Glu Asp Ser Gly Asp Tyr Pro 
145                 150                 155                 160 


Leu Thr Met Ala Gly Pro Gln Trp Lys Lys Phe Lys Ser Ser Phe Cys 
                165                 170                 175     


Glu Phe Ile Gly Val Leu Val Arg Gln Cys Gln Tyr Ser Ile Ile Tyr 
            180                 185                 190         


Asp Glu Tyr Met Met Asp Thr Val Ile Ser Leu Leu Thr Gly Leu Ser 
        195                 200                 205             


Asp Ser Gln Val Arg Ala Phe Arg His Thr Ser Thr Leu Ala Ala Met 
    210                 215                 220                 


Lys Leu Met Thr Ala Leu Val Asn Val Ala Leu Asn Leu Ser Ile Asn 
225                 230                 235                 240 


Met Asp Asn Thr Gln Arg Gln Tyr Glu Ala Glu Arg Asn Lys Met Ile 
                245                 250                 255     


Gly Lys Arg Ala Asn Glu Arg Leu Glu Leu Leu Leu Gln Lys Arg Lys 
            260                 265                 270         


Glu Leu Gln Glu Asn Gln Asp Glu Ile Glu Asn Met Met Asn Ala Ile 
        275                 280                 285             


Phe Lys Gly Val Phe Val His Arg Tyr Arg Asp Ala Ile Ala Glu Ile 
    290                 295                 300                 


Arg Ala Ile Cys Ile Glu Glu Ile Gly Ile Trp Met Lys Met Tyr Ser 
305                 310                 315                 320 


Asp Ala Phe Leu Asn Asp Ser Tyr Leu Lys Tyr Val Gly Trp Thr Met 
                325                 330                 335     


His Asp Lys Gln Gly Glu Val Arg Leu Lys Cys Leu Thr Ala Leu Gln 
            340                 345                 350         


Gly Leu Tyr Tyr Asn Lys Glu Leu Asn Ser Lys Leu Glu Leu Phe Thr 
        355                 360                 365             


Ser Arg Phe Lys Asp Arg Ile Val Ser Met Thr Leu Asp Lys Glu Tyr 
    370                 375                 380                 


Asp Val Ala Val Gln Ala Ile Lys Leu Leu Thr Leu Val Leu Gln Ser 
385                 390                 395                 400 


Ser Glu Glu Val Leu Thr Ala Glu Asp Cys Glu Asn Val Tyr His Leu 
                405                 410                 415     


Val Tyr Ser Ala His Arg Pro Val Ala Val Ala Ala Gly Glu Phe Leu 
            420                 425                 430         


Tyr Lys Lys Leu Phe Ser Arg Arg Asp Pro Glu Glu Asp Gly Met Met 
        435                 440                 445             


Lys Arg Arg Gly Arg Gln Gly Pro Asn Ala Asn Leu Val Lys Thr Leu 
    450                 455                 460                 


Val Phe Phe Phe Leu Glu Ser Glu Leu His Glu His Ala Ala Tyr Leu 
465                 470                 475                 480 


Val Asp Ser Met Trp Asp Cys Ala Thr Glu Leu Leu Lys Asp Trp Glu 
                485                 490                 495     


Cys Met Asn Ser Leu Leu Leu Glu Glu Pro Leu Ser Gly Glu Glu Ala 
            500                 505                 510         


Leu Thr Asp Arg Gln Glu Ser Ala Leu Ile Glu Ile Met Leu Cys Thr 
        515                 520                 525             


Ile Arg Gln Ala Ala Glu Cys His Pro Pro Val Gly Arg Gly Thr Gly 
    530                 535                 540                 


Lys Arg Val Leu Thr Ala Lys Glu Lys Lys Thr Gln Leu Asp Asp Arg 
545                 550                 555                 560 


Thr Lys Ile Thr Glu Leu Phe Ala Val Ala Leu Pro Gln Leu Leu Ala 
                565                 570                 575     


Lys Tyr Ser Val Asp Ala Glu Lys Val Thr Asn Leu Leu Gln Leu Pro 
            580                 585                 590         


Gln Tyr Phe Asp Leu Glu Ile Tyr Thr Thr Gly Arg Leu Glu Lys His 
        595                 600                 605             


Leu Asp Ala Leu Leu Arg Gln Ile Arg Asn Ile Val Glu Lys His Thr 
    610                 615                 620                 


Asp Thr Asp Val Leu Glu Ala Cys Ser Lys Thr Tyr His Ala Leu Cys 
625                 630                 635                 640 


Asn Glu Glu Phe Thr Ile Phe Asn Arg Val Asp Ile Ser Arg Ser Gln 
                645                 650                 655     


Leu Ile Asp Glu Leu Ala Asp Lys Phe Asn Arg Leu Leu Glu Asp Phe 
            660                 665                 670         


Leu Gln Glu Gly Glu Glu Pro Asp Glu Asp Asp Ala Tyr Gln Val Leu 
        675                 680                 685             


Ser Thr Leu Lys Arg Ile Thr Ala Phe His Asn Ala His Asp Leu Ser 
    690                 695                 700                 


Lys Trp Asp Leu Phe Ala Cys Asn Tyr Lys Leu Leu Lys Thr Gly Ile 
705                 710                 715                 720 


Glu Asn Gly Asp Met Pro Glu Gln Ile Val Ile His Ala Leu Gln Cys 
                725                 730                 735     


Thr His Tyr Val Ile Leu Trp Gln Leu Ala Lys Ile Thr Glu Ser Ser 
            740                 745                 750         


Ser Thr Lys Glu Asp Leu Leu Arg Leu Lys Lys Gln Met Arg Val Phe 
        755                 760                 765             


Cys Gln Ile Cys Gln His Tyr Leu Thr Asn Val Asn Thr Thr Val Lys 
    770                 775                 780                 


Glu Gln Ala Phe Thr Ile Leu Cys Asp Ile Leu Met Ile Phe Ser His 
785                 790                 795                 800 


Gln Ile Met Ser Gly Gly Arg Asp Met Leu Glu Pro Leu Val Tyr Thr 
                805                 810                 815     


Pro Asp Ser Ser Leu Gln Ser Glu Leu Leu Ser Phe Ile Leu Asp His 
            820                 825                 830         


Val Phe Ile Glu Gln Asp Asp Asp Asn Asn Ser Ala Asp Gly Gln Gln 
        835                 840                 845             


Glu Asp Glu Ala Ser Lys Ile Glu Ala Leu His Lys Arg Arg Asn Leu 
    850                 855                 860                 


Leu Ala Ala Phe Cys Lys Leu Ile Val Tyr Thr Val Val Glu Met Asn 
865                 870                 875                 880 


Thr Ala Ala Asp Ile Phe Lys Gln Tyr Met Lys Tyr Tyr Asn Asp Tyr 
                885                 890                 895     


Gly Asp Ile Ile Lys Glu Thr Met Ser Lys Thr Arg Gln Ile Asp Lys 
            900                 905                 910         


Ile Gln Cys Ala Lys Thr Leu Ile Leu Ser Leu Gln Gln Leu Phe Asn 
        915                 920                 925             


Glu Met Ile Gln Glu Asn Gly Tyr Asn Phe Asp Arg Ser Ser Ser Thr 
    930                 935                 940                 


Phe Ser Gly Ile Lys Glu Leu Ala Arg Arg Phe Ala Leu Thr Phe Gly 
945                 950                 955                 960 


Leu Asp Gln Leu Lys Thr Arg Glu Ala Ile Ala Met Leu His Lys Asp 
                965                 970                 975     


Gly Ile Glu Phe Ala Phe Lys Glu Pro Asn Pro Gln Gly Glu Ser His 
            980                 985                 990         


Pro Pro Leu Asn Leu Ala Phe Leu  Asp Ile Leu Ser Glu  Phe Ser Ser 
        995                 1000                 1005             


Lys Leu  Leu Arg Gln Asp Lys  Arg Thr Val Tyr Val  Tyr Leu Glu 
    1010                 1015                 1020             


Lys Phe  Met Thr Phe Gln Met  Ser Leu Arg Arg Glu  Asp Val Trp 
    1025                 1030                 1035             


Leu Pro  Leu Met Ser Tyr Arg  Asn Ser Leu Leu Ala  Gly Gly Asp 
    1040                 1045                 1050             


Asp Asp  Thr Met Ser Val Ile  Ser Gly Ile Ser Ser  Arg Gly Ser 
    1055                 1060                 1065             


Thr Val  Arg Ser Lys Lys Ser  Lys Pro Ser Thr Gly  Lys Arg Lys 
    1070                 1075                 1080             


Val Val  Glu Gly Met Gln Leu  Ser Leu Thr Glu Glu  Ser Ser Ser 
    1085                 1090                 1095             


Ser Asp  Ser Met Trp Leu Ser  Arg Glu Gln Thr Leu  His Thr Pro 
    1100                 1105                 1110             


Val Met  Met Gln Thr Pro Gln  Leu Thr Ser Thr Ile  Met Arg Glu 
    1115                 1120                 1125             


Pro Lys  Arg Leu Arg Pro Glu  Asp Ser Phe Met Ser  Val Tyr Pro 
    1130                 1135                 1140             


Met Gln  Thr Glu His His Gln  Thr Pro Leu Asp Tyr  Asn Arg Arg 
    1145                 1150                 1155             


Gly Thr  Ser Leu Met Glu Asp  Asp Glu Glu Pro Ile  Val Glu Asp 
    1160                 1165                 1170             


Val Met  Met Ser Ser Glu Gly  Arg Ile Glu Asp Leu  Asn Glu Gly 
    1175                 1180                 1185             


Met Asp  Phe Asp Thr Met Asp  Ile Asp Leu Pro Pro  Ser Lys Asn 
    1190                 1195                 1200             


Arg Arg  Glu Arg Thr Glu Leu  Lys Pro Asp Phe Phe  Asp Pro Ala 
    1205                 1210                 1215             


Ser Ile  Met Asp Glu Ser Val  Leu Gly Val Ser Met  Phe 
    1220                 1225                 1230     


<210>  4196
<211>  1268
<212>  PRT
<213>  homo sapiens

<400>  4196

Met Ile Ala Ala Pro Glu Ile Pro Thr Asp Phe Asn Leu Leu Gln Glu 
1               5                   10                  15      


Ser Glu Thr His Phe Ser Ser Asp Thr Asp Phe Glu Asp Ile Glu Gly 
            20                  25                  30          


Lys Asn Gln Lys Gln Gly Lys Gly Lys Thr Cys Lys Lys Gly Lys Lys 
        35                  40                  45              


Gly Pro Ala Glu Lys Gly Lys Gly Gly Asn Gly Gly Gly Lys Pro Pro 
    50                  55                  60                  


Ser Gly Pro Asn Arg Met Asn Gly His His Gln Gln Asn Gly Val Glu 
65                  70                  75                  80  


Asn Met Met Leu Phe Glu Val Val Lys Met Gly Lys Ser Ala Met Gln 
                85                  90                  95      


Ser Val Val Asp Asp Trp Ile Glu Ser Tyr Lys His Asp Arg Asp Ile 
            100                 105                 110         


Ala Leu Leu Asp Leu Ile Asn Phe Phe Ile Gln Cys Ser Gly Cys Lys 
        115                 120                 125             


Gly Val Val Thr Ala Glu Met Phe Arg His Met Gln Asn Ser Glu Ile 
    130                 135                 140                 


Ile Arg Lys Met Thr Glu Glu Phe Asp Glu Asp Ser Gly Asp Tyr Pro 
145                 150                 155                 160 


Leu Thr Met Ala Gly Pro Gln Trp Lys Lys Phe Lys Ser Ser Phe Cys 
                165                 170                 175     


Glu Phe Ile Gly Val Leu Val Arg Gln Cys Gln Tyr Ser Ile Ile Tyr 
            180                 185                 190         


Asp Glu Tyr Met Met Asp Thr Val Ile Ser Leu Leu Thr Gly Leu Ser 
        195                 200                 205             


Asp Ser Gln Val Arg Ala Phe Arg His Thr Ser Thr Leu Ala Ala Met 
    210                 215                 220                 


Lys Leu Met Thr Ala Leu Val Asn Val Ala Leu Asn Leu Ser Ile Asn 
225                 230                 235                 240 


Met Asp Asn Thr Gln Arg Gln Tyr Glu Ala Glu Arg Asn Lys Met Ile 
                245                 250                 255     


Gly Lys Arg Ala Asn Glu Arg Leu Glu Leu Leu Leu Gln Lys Arg Lys 
            260                 265                 270         


Glu Leu Gln Glu Asn Gln Asp Glu Ile Glu Asn Met Met Asn Ala Ile 
        275                 280                 285             


Phe Lys Gly Val Phe Val His Arg Tyr Arg Asp Ala Ile Ala Glu Ile 
    290                 295                 300                 


Arg Ala Ile Cys Ile Glu Glu Ile Gly Ile Trp Met Lys Met Tyr Ser 
305                 310                 315                 320 


Asp Ala Phe Leu Asn Asp Ser Tyr Leu Lys Tyr Val Gly Trp Thr Met 
                325                 330                 335     


His Asp Lys Gln Gly Glu Val Arg Leu Lys Cys Leu Thr Ala Leu Gln 
            340                 345                 350         


Gly Leu Tyr Tyr Asn Lys Glu Leu Asn Ser Lys Leu Glu Leu Phe Thr 
        355                 360                 365             


Ser Arg Phe Lys Asp Arg Ile Val Ser Met Thr Leu Asp Lys Glu Tyr 
    370                 375                 380                 


Asp Val Ala Val Gln Ala Ile Lys Leu Leu Thr Leu Val Leu Gln Ser 
385                 390                 395                 400 


Ser Glu Glu Val Leu Thr Ala Glu Asp Cys Glu Asn Val Tyr His Leu 
                405                 410                 415     


Val Tyr Ser Ala His Arg Pro Val Ala Val Ala Ala Gly Glu Phe Leu 
            420                 425                 430         


Tyr Lys Lys Leu Phe Ser Arg Arg Asp Pro Glu Glu Asp Gly Met Met 
        435                 440                 445             


Lys Arg Arg Gly Arg Gln Gly Pro Asn Ala Asn Leu Val Lys Thr Leu 
    450                 455                 460                 


Val Phe Phe Phe Leu Glu Ser Glu Leu His Glu His Ala Ala Tyr Leu 
465                 470                 475                 480 


Val Asp Ser Met Trp Asp Cys Ala Thr Glu Leu Leu Lys Asp Trp Glu 
                485                 490                 495     


Cys Met Asn Ser Leu Leu Leu Glu Glu Pro Leu Ser Gly Glu Glu Ala 
            500                 505                 510         


Leu Thr Asp Arg Gln Glu Ser Ala Leu Ile Glu Ile Met Leu Cys Thr 
        515                 520                 525             


Ile Arg Gln Ala Ala Glu Cys His Pro Pro Val Gly Arg Gly Thr Gly 
    530                 535                 540                 


Lys Arg Val Leu Thr Ala Lys Glu Lys Lys Thr Gln Leu Asp Asp Arg 
545                 550                 555                 560 


Thr Lys Ile Thr Glu Leu Phe Ala Val Ala Leu Pro Gln Leu Leu Ala 
                565                 570                 575     


Lys Tyr Ser Val Asp Ala Glu Lys Val Thr Asn Leu Leu Gln Leu Pro 
            580                 585                 590         


Gln Tyr Phe Asp Leu Glu Ile Tyr Thr Thr Gly Arg Leu Glu Lys His 
        595                 600                 605             


Leu Asp Ala Leu Leu Arg Gln Ile Arg Asn Ile Val Glu Lys His Thr 
    610                 615                 620                 


Asp Thr Asp Val Leu Glu Ala Cys Ser Lys Thr Tyr His Ala Leu Cys 
625                 630                 635                 640 


Asn Glu Glu Phe Thr Ile Phe Asn Arg Val Asp Ile Ser Arg Ser Gln 
                645                 650                 655     


Leu Ile Asp Glu Leu Ala Asp Lys Phe Asn Arg Leu Leu Glu Asp Phe 
            660                 665                 670         


Leu Gln Glu Gly Glu Glu Pro Asp Glu Asp Asp Ala Tyr Gln Val Leu 
        675                 680                 685             


Ser Thr Leu Lys Arg Ile Thr Ala Phe His Asn Ala His Asp Leu Ser 
    690                 695                 700                 


Lys Trp Asp Leu Phe Ala Cys Asn Tyr Lys Leu Leu Lys Thr Gly Ile 
705                 710                 715                 720 


Glu Asn Gly Asp Met Pro Glu Gln Ile Val Ile His Ala Leu Gln Cys 
                725                 730                 735     


Thr His Tyr Val Ile Leu Trp Gln Leu Ala Lys Ile Thr Glu Ser Ser 
            740                 745                 750         


Ser Thr Lys Glu Asp Leu Leu Arg Leu Lys Lys Gln Met Arg Val Phe 
        755                 760                 765             


Cys Gln Ile Cys Gln His Tyr Leu Thr Asn Val Asn Thr Thr Val Lys 
    770                 775                 780                 


Glu Gln Ala Phe Thr Ile Leu Cys Asp Ile Leu Met Ile Phe Ser His 
785                 790                 795                 800 


Gln Ile Met Ser Gly Gly Arg Asp Met Leu Glu Pro Leu Val Tyr Thr 
                805                 810                 815     


Pro Asp Ser Ser Leu Gln Ser Glu Leu Leu Ser Phe Ile Leu Asp His 
            820                 825                 830         


Val Phe Ile Glu Gln Asp Asp Asp Asn Asn Ser Ala Asp Gly Gln Gln 
        835                 840                 845             


Glu Asp Glu Ala Ser Lys Ile Glu Ala Leu His Lys Arg Arg Asn Leu 
    850                 855                 860                 


Leu Ala Ala Phe Cys Lys Leu Ile Val Tyr Thr Val Val Glu Met Asn 
865                 870                 875                 880 


Thr Ala Ala Asp Ile Phe Lys Gln Tyr Met Lys Tyr Tyr Asn Asp Tyr 
                885                 890                 895     


Gly Asp Ile Ile Lys Glu Thr Met Ser Lys Thr Arg Gln Ile Asp Lys 
            900                 905                 910         


Ile Gln Cys Ala Lys Thr Leu Ile Leu Ser Leu Gln Gln Leu Phe Asn 
        915                 920                 925             


Glu Met Ile Gln Glu Asn Gly Tyr Asn Phe Asp Arg Ser Ser Ser Thr 
    930                 935                 940                 


Phe Ser Gly Ile Lys Glu Leu Ala Arg Arg Phe Ala Leu Thr Phe Gly 
945                 950                 955                 960 


Leu Asp Gln Leu Lys Thr Arg Glu Ala Ile Ala Met Leu His Lys Asp 
                965                 970                 975     


Gly Ile Glu Phe Ala Phe Lys Glu Pro Asn Pro Gln Gly Glu Ser His 
            980                 985                 990         


Pro Pro Leu Asn Leu Ala Phe Leu  Asp Ile Leu Ser Glu  Phe Ser Ser 
        995                 1000                 1005             


Lys Leu  Leu Arg Gln Asp Lys  Arg Thr Val Tyr Val  Tyr Leu Glu 
    1010                 1015                 1020             


Lys Phe  Met Thr Phe Gln Met  Ser Leu Arg Arg Glu  Asp Val Trp 
    1025                 1030                 1035             


Leu Pro  Leu Met Ser Tyr Arg  Asn Ser Leu Leu Ala  Gly Gly Asp 
    1040                 1045                 1050             


Asp Asp  Thr Met Ser Val Ile  Ser Gly Ile Ser Ser  Arg Gly Ser 
    1055                 1060                 1065             


Thr Val  Arg Ser Lys Lys Ser  Lys Pro Ser Thr Gly  Lys Arg Lys 
    1070                 1075                 1080             


Val Val  Glu Gly Met Gln Leu  Ser Leu Thr Glu Glu  Ser Ser Ser 
    1085                 1090                 1095             


Ser Asp  Ser Met Trp Leu Ser  Arg Glu Gln Thr Leu  His Thr Pro 
    1100                 1105                 1110             


Val Met  Met Gln Thr Pro Gln  Leu Thr Ser Thr Ile  Met Arg Glu 
    1115                 1120                 1125             


Pro Lys  Arg Leu Arg Pro Glu  Asp Ser Phe Met Ser  Val Tyr Pro 
    1130                 1135                 1140             


Met Gln  Thr Glu His His Gln  Thr Pro Leu Asp Tyr  Asn Thr Gln 
    1145                 1150                 1155             


Val Thr  Trp Met Leu Ala Gln  Arg Gln Gln Glu Glu  Ala Arg Gln 
    1160                 1165                 1170             


Gln Gln  Glu Arg Ala Ala Met  Ser Tyr Val Lys Leu  Arg Thr Asn 
    1175                 1180                 1185             


Leu Gln  His Ala Ile Arg Arg  Gly Thr Ser Leu Met  Glu Asp Asp 
    1190                 1195                 1200             


Glu Glu  Pro Ile Val Glu Asp  Val Met Met Ser Ser  Glu Gly Arg 
    1205                 1210                 1215             


Ile Glu  Asp Leu Asn Glu Gly  Met Asp Phe Asp Thr  Met Asp Ile 
    1220                 1225                 1230             


Asp Leu  Pro Pro Ser Lys Asn  Arg Arg Glu Arg Thr  Glu Leu Lys 
    1235                 1240                 1245             


Pro Asp  Phe Phe Asp Pro Ala  Ser Ile Met Asp Glu  Ser Val Leu 
    1250                 1255                 1260             


Gly Val  Ser Met Phe 
    1265             


<210>  4197
<211>  68
<212>  PRT
<213>  homo sapiens

<400>  4197

Met Ser Gly Ser Ser Ser Val Ala Ala Met Lys Lys Val Val Gln Gln 
1               5                   10                  15      


Leu Arg Leu Glu Ala Gly Leu Asn Arg Val Lys Val Ser Gln Ala Ala 
            20                  25                  30          


Ala Asp Leu Lys Gln Phe Cys Leu Gln Asn Ala Gln His Asp Pro Leu 
        35                  40                  45              


Leu Thr Gly Val Ser Ser Ser Thr Asn Pro Phe Arg Pro Gln Lys Val 
    50                  55                  60                  


Cys Ser Phe Leu 
65              


<210>  4198
<211>  371
<212>  PRT
<213>  homo sapiens

<400>  4198

Met Ala Ala Thr Cys Glu Ile Ser Asn Ile Phe Ser Asn Tyr Phe Ser 
1               5                   10                  15      


Ala Met Tyr Ser Ser Glu Asp Ser Thr Leu Ala Ser Val Pro Pro Ala 
            20                  25                  30          


Ala Thr Phe Gly Ala Asp Asp Leu Val Leu Thr Leu Ser Asn Pro Gln 
        35                  40                  45              


Met Ser Leu Glu Gly Thr Glu Lys Ala Ser Trp Leu Gly Glu Gln Pro 
    50                  55                  60                  


Gln Phe Trp Ser Lys Thr Gln Val Leu Asp Trp Ile Ser Tyr Gln Val 
65                  70                  75                  80  


Glu Lys Asn Lys Tyr Asp Ala Ser Ala Ile Asp Phe Ser Arg Cys Asp 
                85                  90                  95      


Met Asp Gly Ala Thr Leu Cys Asn Cys Ala Leu Glu Glu Leu Arg Leu 
            100                 105                 110         


Val Phe Gly Pro Leu Gly Asp Gln Leu His Ala Gln Leu Arg Asp Leu 
        115                 120                 125             


Thr Ser Ser Ser Ser Asp Glu Leu Ser Trp Ile Ile Glu Leu Leu Glu 
    130                 135                 140                 


Lys Asp Gly Met Ala Phe Gln Glu Ala Leu Asp Pro Gly Pro Phe Asp 
145                 150                 155                 160 


Gln Gly Ser Pro Phe Ala Gln Glu Leu Leu Asp Asp Gly Gln Gln Ala 
                165                 170                 175     


Ser Pro Tyr His Pro Gly Ser Cys Gly Ala Gly Ala Pro Ser Pro Gly 
            180                 185                 190         


Ser Ser Asp Val Ser Thr Ala Gly Thr Gly Ala Ser Arg Ser Ser His 
        195                 200                 205             


Ser Ser Asp Ser Gly Gly Ser Asp Val Asp Leu Asp Pro Thr Asp Gly 
    210                 215                 220                 


Lys Leu Phe Pro Ser Asp Gly Phe Arg Asp Cys Lys Lys Gly Asp Pro 
225                 230                 235                 240 


Lys His Gly Lys Arg Lys Arg Gly Arg Pro Arg Lys Leu Ser Lys Glu 
                245                 250                 255     


Tyr Trp Asp Cys Leu Glu Gly Lys Lys Ser Lys His Ala Pro Arg Gly 
            260                 265                 270         


Thr His Leu Trp Glu Phe Ile Arg Asp Ile Leu Ile His Pro Glu Leu 
        275                 280                 285             


Asn Glu Gly Leu Met Lys Trp Glu Asn Arg His Glu Gly Val Phe Lys 
    290                 295                 300                 


Phe Leu Arg Ser Glu Ala Val Ala Gln Leu Trp Gly Gln Lys Lys Lys 
305                 310                 315                 320 


Asn Ser Asn Met Thr Tyr Glu Lys Leu Ser Arg Ala Met Arg Tyr Tyr 
                325                 330                 335     


Tyr Lys Arg Glu Ile Leu Glu Arg Val Asp Gly Arg Arg Leu Val Tyr 
            340                 345                 350         


Lys Phe Gly Lys Asn Ser Ser Gly Trp Lys Glu Glu Glu Val Leu Gln 
        355                 360                 365             


Ser Arg Asn 
    370     


<210>  4199
<211>  1331
<212>  PRT
<213>  homo sapiens

<400>  4199

Met Gln Ala Ala Pro Arg Ala Gly Cys Gly Ala Ala Leu Leu Leu Trp 
1               5                   10                  15      


Ile Val Ser Ser Cys Leu Cys Arg Ala Trp Thr Ala Pro Ser Thr Ser 
            20                  25                  30          


Gln Lys Cys Asp Glu Pro Leu Val Ser Gly Leu Pro His Val Ala Phe 
        35                  40                  45              


Ser Ser Ser Ser Ser Ile Ser Gly Ser Tyr Ser Pro Gly Tyr Ala Lys 
    50                  55                  60                  


Ile Asn Lys Arg Gly Gly Ala Gly Gly Trp Ser Pro Ser Asp Ser Asp 
65                  70                  75                  80  


His Tyr Gln Trp Leu Gln Val Asp Phe Gly Asn Arg Lys Gln Ile Ser 
                85                  90                  95      


Ala Ile Ala Thr Gln Gly Arg Tyr Ser Ser Ser Asp Trp Val Thr Gln 
            100                 105                 110         


Tyr Arg Met Leu Tyr Ser Asp Thr Gly Arg Asn Trp Lys Pro Tyr His 
        115                 120                 125             


Gln Asp Gly Asn Ile Trp Ala Phe Pro Gly Asn Ile Asn Ser Asp Gly 
    130                 135                 140                 


Val Val Arg His Glu Leu Gln His Pro Ile Ile Ala Arg Tyr Val Arg 
145                 150                 155                 160 


Ile Val Pro Leu Asp Trp Asn Gly Glu Gly Arg Ile Gly Leu Arg Ile 
                165                 170                 175     


Glu Val Tyr Gly Cys Ser Tyr Trp Ala Asp Val Ile Asn Phe Asp Gly 
            180                 185                 190         


His Val Val Leu Pro Tyr Arg Phe Arg Asn Lys Lys Met Lys Thr Leu 
        195                 200                 205             


Lys Asp Val Ile Ala Leu Asn Phe Lys Thr Ser Glu Ser Glu Gly Val 
    210                 215                 220                 


Ile Leu His Gly Glu Gly Gln Gln Gly Asp Tyr Ile Thr Leu Glu Leu 
225                 230                 235                 240 


Lys Lys Ala Lys Leu Val Leu Ser Leu Asn Leu Gly Ser Asn Gln Leu 
                245                 250                 255     


Gly Pro Ile Tyr Gly His Thr Ser Val Met Thr Gly Ser Leu Leu Asp 
            260                 265                 270         


Asp His His Trp His Ser Val Val Ile Glu Arg Gln Gly Arg Ser Ile 
        275                 280                 285             


Asn Leu Thr Leu Asp Arg Ser Met Gln His Phe Arg Thr Asn Gly Glu 
    290                 295                 300                 


Phe Asp Tyr Leu Asp Leu Asp Tyr Glu Ile Thr Phe Gly Gly Ile Pro 
305                 310                 315                 320 


Phe Ser Gly Lys Pro Ser Ser Ser Ser Arg Lys Asn Phe Lys Gly Cys 
                325                 330                 335     


Met Glu Ser Ile Asn Tyr Asn Gly Val Asn Ile Thr Asp Leu Ala Arg 
            340                 345                 350         


Arg Lys Lys Leu Glu Pro Ser Asn Val Gly Asn Leu Ser Phe Ser Cys 
        355                 360                 365             


Val Glu Pro Tyr Thr Val Pro Val Phe Phe Asn Ala Thr Ser Tyr Leu 
    370                 375                 380                 


Glu Val Pro Gly Arg Leu Asn Gln Asp Leu Phe Ser Val Ser Phe Gln 
385                 390                 395                 400 


Phe Arg Thr Trp Asn Pro Asn Gly Leu Leu Val Phe Ser His Phe Ala 
                405                 410                 415     


Asp Asn Leu Gly Asn Val Glu Ile Asp Leu Thr Glu Ser Lys Val Gly 
            420                 425                 430         


Val His Ile Asn Ile Thr Gln Thr Lys Met Ser Gln Ile Asp Ile Ser 
        435                 440                 445             


Ser Gly Ser Gly Leu Asn Asp Gly Gln Trp His Glu Val Arg Phe Leu 
    450                 455                 460                 


Ala Lys Glu Asn Phe Ala Ile Leu Thr Ile Asp Gly Asp Glu Ala Ser 
465                 470                 475                 480 


Ala Val Arg Thr Asn Ser Pro Leu Gln Val Lys Thr Gly Glu Lys Tyr 
                485                 490                 495     


Phe Phe Gly Gly Phe Leu Asn Gln Met Asn Asn Ser Ser His Ser Val 
            500                 505                 510         


Leu Gln Pro Ser Phe Gln Gly Cys Met Gln Leu Ile Gln Val Asp Asp 
        515                 520                 525             


Gln Leu Val Asn Leu Tyr Glu Val Ala Gln Arg Lys Pro Gly Ser Phe 
    530                 535                 540                 


Ala Asn Val Ser Ile Asp Met Cys Ala Ile Ile Asp Arg Cys Val Pro 
545                 550                 555                 560 


Asn His Cys Glu His Gly Gly Lys Cys Ser Gln Thr Trp Asp Ser Phe 
                565                 570                 575     


Lys Cys Thr Cys Asp Glu Thr Gly Tyr Ser Gly Ala Thr Cys His Asn 
            580                 585                 590         


Ser Ile Tyr Glu Pro Ser Cys Glu Ala Tyr Lys His Leu Gly Gln Thr 
        595                 600                 605             


Ser Asn Tyr Tyr Trp Ile Asp Pro Asp Gly Ser Gly Pro Leu Gly Pro 
    610                 615                 620                 


Leu Lys Val Tyr Cys Asn Met Thr Glu Asp Lys Val Trp Thr Ile Val 
625                 630                 635                 640 


Ser His Asp Leu Gln Met Gln Thr Pro Val Val Gly Tyr Asn Pro Glu 
                645                 650                 655     


Lys Tyr Ser Val Thr Gln Leu Val Tyr Ser Ala Ser Met Asp Gln Ile 
            660                 665                 670         


Ser Ala Ile Thr Asp Ser Ala Glu Tyr Cys Glu Gln Tyr Val Ser Tyr 
        675                 680                 685             


Phe Cys Lys Met Ser Arg Leu Leu Asn Thr Pro Asp Gly Ser Pro Tyr 
    690                 695                 700                 


Thr Trp Trp Val Gly Lys Ala Asn Glu Lys His Tyr Tyr Trp Gly Gly 
705                 710                 715                 720 


Ser Gly Pro Gly Ile Gln Lys Cys Ala Cys Gly Ile Glu Arg Asn Cys 
                725                 730                 735     


Thr Asp Pro Lys Tyr Tyr Cys Asn Cys Asp Ala Asp Tyr Lys Gln Trp 
            740                 745                 750         


Arg Lys Asp Ala Gly Phe Leu Ser Tyr Lys Asp His Leu Pro Val Ser 
        755                 760                 765             


Gln Val Val Val Gly Asp Thr Asp Arg Gln Gly Ser Glu Ala Lys Leu 
    770                 775                 780                 


Ser Val Gly Pro Leu Arg Cys Gln Gly Asp Arg Asn Tyr Trp Asn Ala 
785                 790                 795                 800 


Ala Ser Phe Pro Asn Pro Ser Ser Tyr Leu His Phe Ser Thr Phe Gln 
                805                 810                 815     


Gly Glu Thr Ser Ala Asp Ile Ser Phe Tyr Phe Lys Thr Leu Thr Pro 
            820                 825                 830         


Trp Gly Val Phe Leu Glu Asn Met Gly Lys Glu Asp Phe Ile Lys Leu 
        835                 840                 845             


Glu Leu Lys Ser Ala Thr Glu Val Ser Phe Ser Phe Asp Val Gly Asn 
    850                 855                 860                 


Gly Pro Val Glu Ile Val Val Arg Ser Pro Thr Pro Leu Asn Asp Asp 
865                 870                 875                 880 


Gln Trp His Arg Val Thr Ala Glu Arg Asn Val Lys Gln Ala Ser Leu 
                885                 890                 895     


Gln Val Asp Arg Leu Pro Gln Gln Ile Arg Lys Ala Pro Thr Glu Gly 
            900                 905                 910         


His Thr Arg Leu Glu Leu Tyr Ser Gln Leu Phe Val Gly Gly Ala Gly 
        915                 920                 925             


Gly Gln Gln Gly Phe Leu Gly Cys Ile Arg Ser Leu Arg Met Asn Gly 
    930                 935                 940                 


Val Thr Leu Asp Leu Glu Glu Arg Ala Lys Val Thr Ser Gly Phe Ile 
945                 950                 955                 960 


Ser Gly Cys Ser Gly His Cys Thr Ser Tyr Gly Thr Asn Cys Glu Asn 
                965                 970                 975     


Gly Gly Lys Cys Leu Glu Arg Tyr His Gly Tyr Ser Cys Asp Cys Ser 
            980                 985                 990         


Asn Thr Ala Tyr Asp Gly Thr Phe  Cys Asn Lys Asp Val  Gly Ala Phe 
        995                 1000                 1005             


Phe Glu  Glu Gly Met Trp Leu  Arg Tyr Asn Phe Gln  Ala Pro Ala 
    1010                 1015                 1020             


Thr Asn  Ala Arg Asp Ser Ser  Ser Arg Val Asp Asn  Ala Pro Asp 
    1025                 1030                 1035             


Gln Gln  Asn Ser His Pro Asp  Leu Ala Gln Glu Glu  Ile Arg Phe 
    1040                 1045                 1050             


Ser Phe  Ser Thr Thr Lys Ala  Pro Cys Ile Leu Leu  Tyr Ile Ser 
    1055                 1060                 1065             


Ser Phe  Thr Thr Asp Phe Leu  Ala Val Leu Val Lys  Pro Thr Gly 
    1070                 1075                 1080             


Ser Leu  Gln Ile Arg Tyr Asn  Leu Gly Gly Thr Arg  Glu Pro Tyr 
    1085                 1090                 1095             


Asn Ile  Asp Val Asp His Arg  Asn Met Ala Asn Gly  Gln Pro His 
    1100                 1105                 1110             


Ser Val  Asn Ile Thr Arg His  Glu Lys Thr Ile Phe  Leu Lys Leu 
    1115                 1120                 1125             


Asp His  Tyr Pro Ser Val Ser  Tyr His Leu Pro Ser  Ser Ser Asp 
    1130                 1135                 1140             


Thr Leu  Phe Asn Ser Pro Lys  Ser Leu Phe Leu Gly  Lys Val Ile 
    1145                 1150                 1155             


Glu Thr  Gly Lys Ile Asp Gln  Glu Ile His Lys Tyr  Asn Thr Pro 
    1160                 1165                 1170             


Gly Phe  Thr Gly Cys Leu Ser  Arg Val Gln Phe Asn  Gln Ile Ala 
    1175                 1180                 1185             


Pro Leu  Lys Ala Ala Leu Arg  Gln Thr Asn Ala Ser  Ala His Val 
    1190                 1195                 1200             


His Ile  Gln Gly Glu Leu Val  Glu Ser Asn Cys Gly  Ala Ser Pro 
    1205                 1210                 1215             


Leu Thr  Leu Ser Pro Met Ser  Ser Ala Thr Asp Pro  Trp His Leu 
    1220                 1225                 1230             


Asp His  Leu Asp Ser Ala Ser  Ala Asp Phe Pro Tyr  Asn Pro Gly 
    1235                 1240                 1245             


Gln Gly  Gln Ala Ile Arg Asn  Gly Val Asn Arg Asn  Ser Ala Ile 
    1250                 1255                 1260             


Ile Gly  Gly Val Ile Ala Val  Val Ile Phe Thr Ile  Leu Cys Thr 
    1265                 1270                 1275             


Leu Val  Phe Leu Ile Arg Tyr  Met Phe Arg His Lys  Gly Thr Tyr 
    1280                 1285                 1290             


His Thr  Asn Glu Ala Lys Gly  Ala Glu Ser Ala Glu  Ser Ala Asp 
    1295                 1300                 1305             


Ala Ala  Ile Met Asn Asn Asp  Pro Asn Phe Thr Glu  Thr Ile Asp 
    1310                 1315                 1320             


Glu Ser  Lys Lys Glu Trp Leu  Ile 
    1325                 1330     


<210>  4200
<211>  706
<212>  PRT
<213>  homo sapiens

<400>  4200

Met Asn Pro Gln Gln Gln Arg Met Ala Ala Ile Gly Thr Asp Lys Glu 
1               5                   10                  15      


Leu Ser Asp Leu Leu Asp Phe Ser Ala Met Phe Ser Pro Pro Val Asn 
            20                  25                  30          


Ser Gly Lys Thr Arg Pro Thr Thr Leu Gly Ser Ser Gln Phe Ser Gly 
        35                  40                  45              


Ser Gly Ile Asp Glu Arg Gly Gly Thr Thr Ser Trp Gly Thr Ser Gly 
    50                  55                  60                  


Gln Pro Ser Pro Ser Tyr Asp Ser Ser Arg Gly Phe Thr Asp Ser Pro 
65                  70                  75                  80  


His Tyr Ser Asp His Leu Asn Asp Ser Arg Leu Gly Ala His Glu Gly 
                85                  90                  95      


Leu Ser Pro Thr Pro Phe Met Asn Ser Asn Leu Met Gly Lys Thr Ser 
            100                 105                 110         


Glu Arg Gly Ser Phe Ser Leu Tyr Ser Arg Asp Thr Gly Leu Pro Gly 
        115                 120                 125             


Cys Gln Ser Ser Leu Leu Arg Gln Asp Leu Gly Leu Gly Ser Pro Ala 
    130                 135                 140                 


Gln Leu Ser Ser Ser Gly Lys Pro Gly Thr Ala Tyr Tyr Ser Phe Ser 
145                 150                 155                 160 


Ala Thr Ser Ser Arg Arg Arg Pro Leu His Asp Ser Ala Ala Leu Asp 
                165                 170                 175     


Pro Leu Gln Ala Lys Lys Val Arg Lys Val Pro Pro Gly Leu Pro Ser 
            180                 185                 190         


Ser Val Tyr Ala Pro Ser Pro Asn Ser Asp Asp Phe Asn Arg Glu Ser 
        195                 200                 205             


Pro Ser Tyr Pro Ser Pro Lys Pro Pro Thr Ser Met Phe Ala Ser Thr 
    210                 215                 220                 


Phe Phe Met Gln Asp Gly Thr His Asn Ser Ser Asp Leu Trp Ser Ser 
225                 230                 235                 240 


Ser Asn Gly Met Ser Gln Pro Gly Phe Gly Gly Ile Leu Gly Thr Ser 
                245                 250                 255     


Thr Ser His Met Ser Gln Ser Ser Ser Tyr Gly Asn Leu His Ser His 
            260                 265                 270         


Asp Arg Leu Ser Tyr Pro Pro His Ser Val Ser Pro Thr Asp Ile Asn 
        275                 280                 285             


Thr Ser Leu Pro Pro Met Ser Ser Phe His Arg Gly Ser Thr Ser Ser 
    290                 295                 300                 


Ser Pro Tyr Val Ala Ala Ser His Thr Pro Pro Ile Asn Gly Ser Asp 
305                 310                 315                 320 


Ser Ile Leu Gly Thr Arg Gly Asn Ala Ala Gly Ser Ser Gln Thr Gly 
                325                 330                 335     


Asp Ala Leu Gly Lys Ala Leu Ala Ser Ile Tyr Ser Pro Asp His Thr 
            340                 345                 350         


Ser Ser Ser Phe Pro Ser Asn Pro Ser Thr Pro Val Gly Ser Pro Ser 
        355                 360                 365             


Pro Leu Thr Gly Thr Ser Gln Trp Pro Arg Pro Gly Gly Gln Ala Pro 
    370                 375                 380                 


Ser Ser Pro Ser Tyr Glu Asn Ser Leu His Ser Leu Lys Asn Arg Val 
385                 390                 395                 400 


Glu Gln Gln Leu His Glu His Leu Gln Asp Ala Met Ser Phe Leu Lys 
                405                 410                 415     


Asp Val Cys Glu Gln Ser Arg Met Glu Asp Arg Leu Asp Arg Leu Asp 
            420                 425                 430         


Asp Ala Ile His Val Leu Arg Asn His Ala Val Gly Pro Ser Thr Ser 
        435                 440                 445             


Leu Pro Ala Gly His Ser Asp Ile His Ser Leu Leu Gly Pro Ser His 
    450                 455                 460                 


Asn Ala Pro Ile Gly Ser Leu Asn Ser Asn Tyr Gly Gly Ser Ser Leu 
465                 470                 475                 480 


Val Ala Ser Ser Arg Ser Ala Ser Met Val Gly Thr His Arg Glu Asp 
                485                 490                 495     


Ser Val Ser Leu Asn Gly Asn His Ser Val Leu Ser Ser Thr Val Thr 
            500                 505                 510         


Thr Ser Ser Thr Asp Leu Asn His Lys Thr Gln Glu Asn Tyr Arg Gly 
        515                 520                 525             


Gly Leu Gln Ser Gln Ser Gly Thr Val Val Thr Thr Glu Ile Lys Thr 
    530                 535                 540                 


Glu Asn Lys Glu Lys Asp Glu Asn Leu His Glu Pro Pro Ser Ser Asp 
545                 550                 555                 560 


Asp Met Lys Ser Asp Asp Glu Ser Ser Gln Lys Asp Ile Lys Val Ser 
                565                 570                 575     


Ser Arg Gly Arg Thr Ser Ser Thr Asn Glu Asp Glu Asp Leu Asn Pro 
            580                 585                 590         


Glu Gln Lys Ile Glu Arg Glu Lys Glu Arg Arg Met Ala Asn Asn Ala 
        595                 600                 605             


Arg Glu Arg Leu Arg Val Arg Asp Ile Asn Glu Ala Phe Lys Glu Leu 
    610                 615                 620                 


Gly Arg Met Cys Gln Leu His Leu Lys Ser Glu Lys Pro Gln Thr Lys 
625                 630                 635                 640 


Leu Leu Ile Leu His Gln Ala Val Ala Val Ile Leu Ser Leu Glu Gln 
                645                 650                 655     


Gln Val Arg Glu Arg Asn Leu Asn Pro Lys Ala Ala Cys Leu Lys Arg 
            660                 665                 670         


Arg Glu Glu Glu Lys Val Ser Ala Val Ser Ala Glu Pro Pro Thr Thr 
        675                 680                 685             


Leu Pro Gly Thr His Pro Gly Leu Ser Glu Thr Thr Asn Pro Met Gly 
    690                 695                 700                 


His Met 
705     


<210>  4201
<211>  919
<212>  PRT
<213>  homo sapiens

<400>  4201

Met Ala Ser Ala Thr Ala Ala Ala Ala Arg Arg Gly Leu Gly Arg Ala 
1               5                   10                  15      


Leu Pro Leu Leu Trp Arg Gly Tyr Gln Thr Glu Arg Gly Val Tyr Gly 
            20                  25                  30          


Tyr Arg Pro Arg Lys Pro Glu Ser Arg Glu Pro Gln Gly Ala Leu Glu 
        35                  40                  45              


Arg Pro Pro Val Asp His Gly Leu Ala Arg Leu Val Thr Val Tyr Cys 
    50                  55                  60                  


Glu His Gly His Lys Ala Ala Lys Ile Asn Pro Leu Phe Thr Gly Gln 
65                  70                  75                  80  


Ala Leu Leu Glu Asn Val Pro Glu Ile Gln Ala Leu Val Gln Thr Leu 
                85                  90                  95      


Gln Gly Pro Phe His Thr Ala Gly Leu Leu Asn Met Gly Lys Glu Glu 
            100                 105                 110         


Ala Ser Leu Glu Glu Val Leu Val Tyr Leu Asn Gln Ile Tyr Cys Gly 
        115                 120                 125             


Gln Ile Ser Ile Glu Thr Ser Gln Leu Gln Ser Gln Asp Glu Lys Asp 
    130                 135                 140                 


Trp Phe Ala Lys Arg Phe Glu Glu Leu Gln Lys Glu Thr Phe Thr Thr 
145                 150                 155                 160 


Glu Glu Arg Lys His Leu Ser Lys Leu Met Leu Glu Ser Gln Glu Phe 
                165                 170                 175     


Asp His Phe Leu Ala Thr Lys Phe Ser Thr Val Lys Arg Tyr Gly Gly 
            180                 185                 190         


Glu Gly Ala Glu Ser Met Met Gly Phe Phe His Glu Leu Leu Lys Met 
        195                 200                 205             


Ser Ala Tyr Ser Gly Ile Thr Asp Val Ile Ile Gly Met Pro His Arg 
    210                 215                 220                 


Gly Arg Leu Asn Leu Leu Thr Gly Leu Leu Gln Phe Pro Pro Glu Leu 
225                 230                 235                 240 


Met Phe Arg Lys Met Arg Gly Leu Ser Glu Phe Pro Glu Asn Phe Ser 
                245                 250                 255     


Ala Thr Gly Asp Val Leu Ser His Leu Thr Ser Ser Val Asp Leu Tyr 
            260                 265                 270         


Phe Gly Ala His His Pro Leu His Val Thr Met Leu Pro Asn Pro Ser 
        275                 280                 285             


His Leu Glu Ala Val Asn Pro Val Ala Val Gly Lys Thr Arg Gly Arg 
    290                 295                 300                 


Gln Gln Ser Arg Gln Asp Gly Asp Tyr Ser Pro Asp Asn Ser Ala Gln 
305                 310                 315                 320 


Pro Gly Asp Arg Val Ile Cys Leu Gln Val His Gly Asp Ala Ser Phe 
                325                 330                 335     


Cys Gly Gln Gly Ile Val Pro Glu Thr Phe Thr Leu Ser Asn Leu Pro 
            340                 345                 350         


His Phe Arg Ile Gly Gly Ser Val His Leu Ile Val Asn Asn Gln Leu 
        355                 360                 365             


Gly Tyr Thr Thr Pro Ala Glu Arg Gly Arg Ser Ser Leu Tyr Cys Ser 
    370                 375                 380                 


Asp Ile Gly Lys Leu Val Gly Cys Ala Ile Ile His Val Asn Gly Asp 
385                 390                 395                 400 


Ser Pro Glu Glu Val Val Arg Ala Thr Arg Leu Ala Phe Glu Tyr Gln 
                405                 410                 415     


Arg Gln Phe Arg Lys Asp Val Ile Ile Asp Leu Leu Cys Tyr Arg Gln 
            420                 425                 430         


Trp Gly His Asn Glu Leu Asp Glu Pro Phe Tyr Thr Asn Pro Ile Met 
        435                 440                 445             


Tyr Lys Ile Ile Arg Ala Arg Lys Ser Ile Pro Asp Thr Tyr Ala Glu 
    450                 455                 460                 


His Leu Ile Ala Gly Gly Leu Met Thr Gln Glu Glu Val Ser Glu Ile 
465                 470                 475                 480 


Lys Ser Ser Tyr Tyr Ala Lys Leu Asn Asp His Leu Asn Asn Met Ala 
                485                 490                 495     


His Tyr Arg Pro Pro Ala Leu Asn Leu Gln Ala His Trp Gln Gly Leu 
            500                 505                 510         


Ala Gln Pro Glu Ala Gln Ile Thr Thr Trp Ser Thr Gly Val Pro Leu 
        515                 520                 525             


Asp Leu Leu Arg Phe Val Gly Met Lys Ser Val Glu Val Pro Arg Glu 
    530                 535                 540                 


Leu Gln Met His Ser His Leu Leu Lys Thr His Val Gln Ser Arg Met 
545                 550                 555                 560 


Glu Lys Met Met Asp Gly Ile Lys Leu Asp Trp Ala Thr Ala Glu Ala 
                565                 570                 575     


Leu Ala Leu Gly Ser Leu Leu Ala Gln Gly Phe Asn Val Arg Leu Ser 
            580                 585                 590         


Gly Gln Asp Val Gly Arg Gly Thr Phe Ser Gln Arg His Ala Ile Val 
        595                 600                 605             


Val Cys Gln Glu Thr Asp Asp Thr Tyr Ile Pro Leu Asn His Met Asp 
    610                 615                 620                 


Pro Asn Gln Lys Gly Phe Leu Glu Val Ser Asn Ser Pro Leu Ser Glu 
625                 630                 635                 640 


Glu Ala Val Leu Gly Phe Glu Tyr Gly Met Ser Ile Glu Ser Pro Lys 
                645                 650                 655     


Leu Leu Pro Leu Trp Glu Ala Gln Phe Gly Asp Phe Phe Asn Gly Ala 
            660                 665                 670         


Gln Ile Ile Phe Asp Thr Phe Ile Ser Gly Gly Glu Ala Lys Trp Leu 
        675                 680                 685             


Leu Gln Ser Gly Ile Val Ile Leu Leu Pro His Gly Tyr Asp Gly Ala 
    690                 695                 700                 


Gly Pro Asp His Ser Ser Cys Arg Ile Glu Arg Phe Leu Gln Met Cys 
705                 710                 715                 720 


Asp Ser Ala Glu Glu Gly Val Asp Gly Asp Thr Val Asn Met Phe Val 
                725                 730                 735     


Val His Pro Thr Thr Pro Ala Gln Tyr Phe His Leu Leu Arg Arg Gln 
            740                 745                 750         


Met Val Arg Asn Phe Arg Lys Pro Leu Ile Val Ala Ser Pro Lys Met 
        755                 760                 765             


Leu Leu Arg Leu Pro Ala Ala Val Ser Thr Leu Gln Glu Met Ala Pro 
    770                 775                 780                 


Gly Thr Thr Phe Asn Pro Val Ile Gly Asp Ser Ser Val Asp Pro Lys 
785                 790                 795                 800 


Lys Val Lys Thr Leu Val Phe Cys Ser Gly Lys His Phe Tyr Ser Leu 
                805                 810                 815     


Val Lys Gln Arg Glu Ser Leu Gly Ala Lys Lys His Asp Phe Ala Ile 
            820                 825                 830         


Ile Arg Val Glu Glu Leu Cys Pro Phe Pro Leu Asp Ser Leu Gln Gln 
        835                 840                 845             


Glu Met Ser Lys Tyr Lys His Val Lys Asp His Ile Trp Ser Gln Glu 
    850                 855                 860                 


Glu Pro Gln Asn Met Gly Pro Trp Ser Phe Val Ser Pro Arg Phe Glu 
865                 870                 875                 880 


Lys Gln Leu Ala Cys Lys Leu Arg Leu Val Gly Arg Pro Pro Leu Pro 
                885                 890                 895     


Val Pro Ala Val Gly Ile Gly Thr Val His Leu His Gln His Glu Asp 
            900                 905                 910         


Ile Leu Ala Lys Thr Phe Ala 
        915                 


<210>  4202
<211>  548
<212>  PRT
<213>  homo sapiens

<400>  4202

Met Ala Thr Gly Ala Asn Ala Thr Pro Leu Asp Phe Pro Ser Lys Lys 
1               5                   10                  15      


Arg Lys Arg Ser Arg Trp Asn Gln Asp Thr Met Glu Gln Lys Thr Val 
            20                  25                  30          


Ile Pro Gly Met Pro Thr Val Ile Pro Pro Gly Leu Thr Arg Glu Gln 
        35                  40                  45              


Glu Arg Ala Tyr Ile Val Gln Leu Gln Ile Glu Asp Leu Thr Arg Lys 
    50                  55                  60                  


Leu Arg Thr Gly Asp Leu Gly Ile Pro Pro Asn Pro Glu Asp Arg Ser 
65                  70                  75                  80  


Pro Ser Pro Glu Pro Ile Tyr Asn Ser Glu Gly Lys Arg Leu Asn Thr 
                85                  90                  95      


Arg Glu Phe Arg Thr Arg Lys Lys Leu Glu Glu Glu Arg His Asn Leu 
            100                 105                 110         


Ile Thr Glu Met Val Ala Leu Asn Pro Asp Phe Lys Pro Pro Ala Asp 
        115                 120                 125             


Tyr Lys Pro Pro Ala Thr Arg Val Ser Asp Lys Val Met Ile Pro Gln 
    130                 135                 140                 


Asp Glu Tyr Pro Glu Ile Asn Phe Val Gly Leu Leu Ile Gly Pro Arg 
145                 150                 155                 160 


Gly Asn Thr Leu Lys Asn Ile Glu Lys Glu Cys Asn Ala Lys Ile Met 
                165                 170                 175     


Ile Arg Gly Lys Gly Ser Val Lys Glu Gly Lys Val Gly Arg Lys Asp 
            180                 185                 190         


Gly Gln Met Leu Pro Gly Glu Asp Glu Pro Leu His Ala Leu Val Thr 
        195                 200                 205             


Ala Asn Thr Met Glu Asn Val Lys Lys Ala Val Glu Gln Ile Arg Asn 
    210                 215                 220                 


Ile Leu Lys Gln Gly Ile Glu Thr Pro Glu Asp Gln Asn Asp Leu Arg 
225                 230                 235                 240 


Lys Met Gln Leu Arg Glu Leu Ala Arg Leu Asn Gly Thr Leu Arg Glu 
                245                 250                 255     


Asp Asp Asn Arg Ile Leu Arg Pro Trp Gln Ser Ser Glu Thr Arg Ser 
            260                 265                 270         


Ile Thr Asn Thr Thr Val Cys Thr Lys Cys Gly Gly Ala Gly His Ile 
        275                 280                 285             


Ala Ser Asp Cys Lys Phe Gln Arg Pro Gly Asp Pro Gln Ser Ala Gln 
    290                 295                 300                 


Asp Lys Ala Arg Met Asp Lys Glu Tyr Leu Ser Leu Met Ala Glu Leu 
305                 310                 315                 320 


Gly Glu Ala Pro Val Pro Ala Ser Val Gly Ser Thr Ser Gly Pro Ala 
                325                 330                 335     


Thr Thr Pro Leu Ala Ser Ala Pro Arg Pro Ala Ala Pro Ala Asn Asn 
            340                 345                 350         


Pro Pro Pro Pro Ser Leu Met Ser Thr Thr Gln Ser Arg Pro Pro Trp 
        355                 360                 365             


Met Asn Ser Gly Pro Ser Glu Ser Arg Pro Tyr His Gly Met His Gly 
    370                 375                 380                 


Gly Gly Pro Gly Gly Pro Gly Gly Gly Pro His Ser Phe Pro His Pro 
385                 390                 395                 400 


Leu Pro Ser Leu Thr Gly Gly His Gly Gly His Pro Met Gln His Asn 
                405                 410                 415     


Pro Asn Gly Pro Pro Pro Pro Trp Met Gln Pro Pro Pro Pro Pro Met 
            420                 425                 430         


Asn Gln Gly Pro His Pro Pro Gly His His Gly Pro Pro Pro Met Asp 
        435                 440                 445             


Gln Tyr Leu Gly Ser Thr Pro Val Gly Ser Gly Val Tyr Arg Leu His 
    450                 455                 460                 


Gln Gly Lys Gly Met Met Pro Pro Pro Pro Met Gly Met Met Pro Pro 
465                 470                 475                 480 


Pro Pro Pro Pro Pro Ser Gly Gln Pro Pro Pro Pro Pro Ser Gly Pro 
                485                 490                 495     


Leu Pro Pro Trp Gln Gln Gln Gln Gln Gln Pro Pro Pro Pro Pro Pro 
            500                 505                 510         


Pro Ser Ser Ser Met Ala Ser Ser Thr Pro Leu Pro Trp Gln Gln Arg 
        515                 520                 525             


Ser Leu Pro Ala Ala Ala Met Ala Arg Ala Met Arg Val Arg Thr Phe 
    530                 535                 540                 


Arg Ala His Trp 
545             


<210>  4203
<211>  365
<212>  PRT
<213>  homo sapiens

<400>  4203

Met Glu Leu Asp Phe Gly His Phe Asp Glu Arg Asp Lys Thr Ser Arg 
1               5                   10                  15      


Asn Met Arg Gly Ser Arg Met Asn Gly Leu Pro Ser Pro Thr His Ser 
            20                  25                  30          


Ala His Cys Ser Phe Tyr Arg Thr Arg Thr Leu Gln Ala Leu Ser Asn 
        35                  40                  45              


Glu Lys Lys Ala Lys Lys Val Arg Phe Tyr Arg Asn Gly Asp Arg Tyr 
    50                  55                  60                  


Phe Lys Gly Ile Val Tyr Ala Val Ser Ser Asp Arg Phe Arg Ser Phe 
65                  70                  75                  80  


Asp Ala Leu Leu Ala Asp Leu Thr Arg Ser Leu Ser Asp Asn Ile Asn 
                85                  90                  95      


Leu Pro Gln Gly Val Arg Tyr Ile Tyr Thr Ile Asp Gly Ser Arg Lys 
            100                 105                 110         


Ile Gly Ser Met Asp Glu Leu Glu Glu Gly Glu Ser Tyr Val Cys Ser 
        115                 120                 125             


Ser Asp Asn Phe Phe Lys Lys Val Glu Tyr Thr Lys Asn Val Asn Pro 
    130                 135                 140                 


Asn Trp Ser Val Asn Val Lys Thr Ser Ala Asn Met Lys Ala Pro Gln 
145                 150                 155                 160 


Ser Leu Ala Ser Ser Asn Ser Ala Gln Ala Arg Glu Asn Lys Asp Phe 
                165                 170                 175     


Val Arg Pro Lys Leu Val Thr Ile Ile Arg Ser Gly Val Lys Pro Arg 
            180                 185                 190         


Lys Ala Val Arg Val Leu Leu Asn Lys Lys Thr Ala His Ser Phe Glu 
        195                 200                 205             


Gln Val Leu Thr Asp Ile Thr Glu Ala Ile Lys Leu Glu Thr Gly Val 
    210                 215                 220                 


Val Lys Lys Leu Tyr Thr Leu Asp Gly Lys Gln Val Thr Cys Leu His 
225                 230                 235                 240 


Asp Phe Phe Gly Asp Asp Asp Val Phe Ile Ala Cys Gly Pro Glu Lys 
                245                 250                 255     


Phe Arg Tyr Ala Gln Asp Asp Phe Ser Leu Asp Glu Asn Glu Cys Arg 
            260                 265                 270         


Val Met Lys Gly Asn Pro Ser Ala Thr Ala Gly Pro Lys Ala Ser Pro 
        275                 280                 285             


Thr Pro Gln Lys Thr Ser Ala Lys Ser Pro Gly Pro Met Arg Arg Ser 
    290                 295                 300                 


Lys Ser Pro Ala Asp Ser Gly Asn Asp Gln Asp Ala Asn Gly Thr Ser 
305                 310                 315                 320 


Ser Ser Gln Leu Ser Thr Pro Lys Ser Lys Gln Ser Pro Ile Ser Thr 
                325                 330                 335     


Pro Thr Ser Pro Gly Ser Leu Arg Lys His Lys Asp Leu Tyr Leu Pro 
            340                 345                 350         


Leu Ser Leu Asp Asp Ser Asp Ser Leu Gly Asp Ser Met 
        355                 360                 365 


<210>  4204
<211>  308
<212>  PRT
<213>  homo sapiens

<400>  4204

Met Phe Asn Gly Glu Pro Gly Pro Ala Ser Ser Gly Ala Ser Arg Asn 
1               5                   10                  15      


Val Val Arg Ser Ser Ser Ile Ser Gly Glu Ile Cys Gly Ser Gln Gln 
            20                  25                  30          


Ala Gly Gly Gly Ala Gly Thr Thr Thr Ala Lys Lys Arg Arg Ser Ser 
        35                  40                  45              


Leu Gly Ala Lys Met Val Ala Ile Val Gly Leu Thr Gln Trp Ser Lys 
    50                  55                  60                  


Ser Thr Leu Gln Leu Pro Gln Pro Glu Gly Ala Thr Lys Lys Leu Arg 
65                  70                  75                  80  


Ser Asn Ile Arg Arg Ser Thr Glu Thr Gly Ile Ala Val Glu Met Arg 
                85                  90                  95      


Ser Arg Val Thr Arg Gln Gly Ser Arg Glu Ser Thr Asp Gly Ser Thr 
            100                 105                 110         


Asn Ser Asn Ser Ser Asp Gly Thr Phe Ile Phe Pro Thr Thr Arg Leu 
        115                 120                 125             


Gly Ala Glu Ser Gln Phe Ser Asp Phe Leu Asp Gly Leu Gly Pro Ala 
    130                 135                 140                 


Gln Ile Val Gly Arg Gln Thr Leu Ala Thr Pro Pro Met Gly Asp Val 
145                 150                 155                 160 


His Ile Ala Ile Met Asp Arg Ser Gly Gln Leu Glu Val Glu Val Ile 
                165                 170                 175     


Glu Ala Arg Gly Leu Thr Pro Lys Pro Gly Ser Lys Ser Leu Pro Ala 
            180                 185                 190         


Thr Tyr Ile Lys Val Tyr Leu Leu Glu Asn Gly Ala Cys Leu Ala Lys 
        195                 200                 205             


Lys Lys Thr Lys Met Thr Lys Lys Thr Cys Asp Pro Leu Tyr Gln Gln 
    210                 215                 220                 


Ala Leu Leu Phe Asp Glu Gly Pro Gln Gly Lys Val Leu Gln Val Ile 
225                 230                 235                 240 


Val Trp Gly Asp Tyr Gly Arg Met Asp His Lys Cys Phe Met Gly Met 
                245                 250                 255     


Ala Gln Ile Met Leu Asp Glu Leu Asp Leu Ser Ala Ala Val Thr Gly 
            260                 265                 270         


Trp Tyr Lys Leu Phe Pro Thr Ser Ser Val Ala Asp Ser Thr Leu Gly 
        275                 280                 285             


Ser Leu Thr Arg Arg Leu Ser Gln Ser Ser Leu Glu Ser Ala Thr Ser 
    290                 295                 300                 


Pro Ser Cys Ser 
305             


<210>  4205
<211>  360
<212>  PRT
<213>  homo sapiens

<400>  4205

Met Ser Leu Val Asp Leu Gly Lys Lys Leu Leu Glu Ala Ala Arg Ala 
1               5                   10                  15      


Gly Gln Asp Asp Glu Val Arg Ile Leu Met Ala Asn Gly Ala Pro Phe 
            20                  25                  30          


Thr Thr Asp Trp Leu Gly Thr Ser Pro Leu His Leu Ala Ala Gln Tyr 
        35                  40                  45              


Gly His Tyr Ser Thr Thr Glu Val Leu Leu Arg Ala Gly Val Ser Arg 
    50                  55                  60                  


Asp Ala Arg Thr Lys Val Asp Arg Thr Pro Leu His Met Ala Ala Ser 
65                  70                  75                  80  


Glu Gly His Ala Ser Ile Val Glu Val Leu Leu Lys His Gly Ala Asp 
                85                  90                  95      


Val Asn Ala Lys Asp Met Leu Lys Met Thr Ala Leu His Trp Ala Thr 
            100                 105                 110         


Glu His Asn His Gln Glu Val Val Glu Leu Leu Ile Lys Tyr Gly Ala 
        115                 120                 125             


Asp Val His Thr Gln Ser Lys Phe Cys Lys Thr Ala Phe Asp Ile Ser 
    130                 135                 140                 


Ile Asp Asn Gly Asn Glu Asp Leu Ala Glu Ile Leu Gln Ile Ala Met 
145                 150                 155                 160 


Gln Asn Gln Ile Asn Thr Asn Pro Glu Ser Pro Asp Thr Val Thr Ile 
                165                 170                 175     


His Ala Ala Thr Pro Gln Phe Ile Ile Gly Pro Gly Gly Val Val Asn 
            180                 185                 190         


Leu Thr Gly Leu Val Ser Ser Glu Asn Ser Ser Lys Ala Thr Asp Glu 
        195                 200                 205             


Thr Gly Val Ser Ala Val Gln Phe Gly Asn Ser Ser Thr Ser Val Leu 
    210                 215                 220                 


Ala Thr Leu Ala Ala Leu Ala Glu Ala Ser Ala Pro Leu Ser Asn Ser 
225                 230                 235                 240 


Ser Glu Thr Pro Val Val Ala Thr Glu Glu Val Val Thr Ala Glu Ser 
                245                 250                 255     


Val Asp Gly Ala Ile Gln Gln Val Val Ser Ser Gly Gly Gln Gln Val 
            260                 265                 270         


Ile Thr Ile Val Thr Asp Gly Ile Gln Leu Gly Asn Leu His Ser Ile 
        275                 280                 285             


Pro Thr Ser Gly Ile Gly Gln Pro Ile Ile Val Thr Met Pro Asp Gly 
    290                 295                 300                 


Gln Gln Val Leu Thr Val Pro Ala Thr Asp Ile Ala Glu Glu Thr Val 
305                 310                 315                 320 


Ile Ser Glu Glu Pro Pro Ala Lys Arg Gln Cys Ile Glu Ile Ile Glu 
                325                 330                 335     


Asn Arg Val Glu Ser Ala Glu Ile Glu Val Arg Ser Leu Leu Pro Gly 
            340                 345                 350         


Val Leu Cys Arg Ser His Pro Lys 
        355                 360 


<210>  4206
<211>  348
<212>  PRT
<213>  homo sapiens

<400>  4206

Met Ser Ala Ala Phe Pro Pro Ser Leu Met Met Met Gln Arg Pro Leu 
1               5                   10                  15      


Gly Ser Ser Thr Ala Phe Ser Ile Asp Ser Leu Ile Gly Ser Pro Pro 
            20                  25                  30          


Gln Pro Ser Pro Gly His Phe Val Tyr Thr Gly Tyr Pro Met Phe Met 
        35                  40                  45              


Pro Tyr Arg Pro Val Val Leu Pro Pro Pro Pro Pro Pro Pro Pro Ala 
    50                  55                  60                  


Leu Pro Gln Ala Ala Leu Gln Pro Ala Leu Pro Pro Ala His Pro His 
65                  70                  75                  80  


His Gln Ile Pro Ser Leu Pro Thr Gly Phe Cys Ser Ser Leu Ala Gln 
                85                  90                  95      


Gly Met Ala Leu Thr Ser Thr Leu Met Ala Thr Leu Pro Gly Gly Phe 
            100                 105                 110         


Ser Ala Ser Pro Gln His Gln Glu Ala Ala Ala Ala Arg Lys Phe Ala 
        115                 120                 125             


Pro Gln Pro Leu Pro Gly Gly Gly Asn Phe Asp Lys Ala Glu Ala Leu 
    130                 135                 140                 


Gln Ala Asp Ala Glu Asp Gly Lys Gly Phe Leu Ala Lys Glu Gly Ser 
145                 150                 155                 160 


Leu Leu Ala Phe Ser Ala Ala Glu Thr Val Gln Ala Ser Leu Val Gly 
                165                 170                 175     


Ala Val Arg Gly Gln Gly Lys Asp Glu Ser Lys Val Glu Asp Asp Pro 
            180                 185                 190         


Lys Gly Lys Glu Glu Ser Phe Ser Leu Glu Ser Asp Val Asp Tyr Ser 
        195                 200                 205             


Ser Asp Asp Asn Leu Thr Gly Gln Ala Ala His Lys Glu Glu Asp Pro 
    210                 215                 220                 


Gly His Ala Leu Glu Glu Thr Pro Pro Ser Ser Gly Ala Ala Gly Ser 
225                 230                 235                 240 


Thr Thr Ser Thr Gly Lys Asn Arg Arg Arg Arg Thr Ala Phe Thr Ser 
                245                 250                 255     


Glu Gln Leu Leu Glu Leu Glu Lys Glu Phe His Cys Lys Lys Tyr Leu 
            260                 265                 270         


Ser Leu Thr Glu Arg Ser Gln Ile Ala His Ala Leu Lys Leu Ser Glu 
        275                 280                 285             


Val Gln Val Lys Ile Trp Phe Gln Asn Arg Arg Ala Lys Trp Lys Arg 
    290                 295                 300                 


Val Lys Ala Gly Asn Ala Asn Ser Lys Thr Gly Glu Pro Ser Arg Asn 
305                 310                 315                 320 


Pro Lys Ile Val Val Pro Ile Pro Val His Val Ser Arg Phe Ala Ile 
                325                 330                 335     


Arg Ser Gln His Gln Gln Leu Glu Gln Ala Arg Pro 
            340                 345             


<210>  4207
<211>  308
<212>  PRT
<213>  homo sapiens

<400>  4207

Met Pro Gly Gln Glu Leu Arg Thr Val Asn Gly Ser Gln Met Leu Leu 
1               5                   10                  15      


Val Leu Leu Val Leu Ser Trp Leu Pro His Gly Gly Ala Leu Ser Leu 
            20                  25                  30          


Ala Glu Ala Ser Arg Ala Ser Phe Pro Gly Pro Ser Glu Leu His Ser 
        35                  40                  45              


Glu Asp Ser Arg Phe Arg Glu Leu Arg Lys Arg Tyr Glu Asp Leu Leu 
    50                  55                  60                  


Thr Arg Leu Arg Ala Asn Gln Ser Trp Glu Asp Ser Asn Thr Asp Leu 
65                  70                  75                  80  


Val Pro Ala Pro Ala Val Arg Ile Leu Thr Pro Glu Val Arg Leu Gly 
                85                  90                  95      


Ser Gly Gly His Leu His Leu Arg Ile Ser Arg Ala Ala Leu Pro Glu 
            100                 105                 110         


Gly Leu Pro Glu Ala Ser Arg Leu His Arg Ala Leu Phe Arg Leu Ser 
        115                 120                 125             


Pro Thr Ala Ser Arg Ser Trp Asp Val Thr Arg Pro Leu Arg Arg Gln 
    130                 135                 140                 


Leu Ser Leu Ala Arg Pro Gln Ala Pro Ala Leu His Leu Arg Leu Ser 
145                 150                 155                 160 


Pro Pro Pro Ser Gln Ser Asp Gln Leu Leu Ala Glu Ser Ser Ser Ala 
                165                 170                 175     


Arg Pro Gln Leu Glu Leu His Leu Arg Pro Gln Ala Ala Arg Gly Arg 
            180                 185                 190         


Arg Arg Ala Arg Ala Arg Asn Gly Asp His Cys Pro Leu Gly Pro Gly 
        195                 200                 205             


Arg Cys Cys Arg Leu His Thr Val Arg Ala Ser Leu Glu Asp Leu Gly 
    210                 215                 220                 


Trp Ala Asp Trp Val Leu Ser Pro Arg Glu Val Gln Val Thr Met Cys 
225                 230                 235                 240 


Ile Gly Ala Cys Pro Ser Gln Phe Arg Ala Ala Asn Met His Ala Gln 
                245                 250                 255     


Ile Lys Thr Ser Leu His Arg Leu Lys Pro Asp Thr Val Pro Ala Pro 
            260                 265                 270         


Cys Cys Val Pro Ala Ser Tyr Asn Pro Met Val Leu Ile Gln Lys Thr 
        275                 280                 285             


Asp Thr Gly Val Ser Leu Gln Thr Tyr Asp Asp Leu Leu Ala Lys Asp 
    290                 295                 300                 


Cys His Cys Ile 
305             


<210>  4208
<211>  208
<212>  PRT
<213>  homo sapiens

<400>  4208

Met Arg Ser Gly Glu Glu Leu Asp Gly Phe Glu Gly Glu Ala Ser Ser 
1               5                   10                  15      


Thr Ser Met Ile Ser Gly Ala Ser Ser Pro Tyr Gln Pro Thr Thr Glu 
            20                  25                  30          


Pro Val Ser Gln Arg Arg Gly Leu Ala Gly Leu Arg Cys Asp Pro Asp 
        35                  40                  45              


Tyr Leu Arg Gly Ala Leu Gly Arg Leu Lys Val Ala Gln Val Ile Leu 
    50                  55                  60                  


Ala Leu Ile Ala Phe Ile Cys Ile Glu Thr Ile Met Ala Cys Ser Pro 
65                  70                  75                  80  


Cys Glu Gly Leu Tyr Phe Phe Glu Phe Val Ser Cys Ser Ala Phe Val 
                85                  90                  95      


Val Thr Gly Val Leu Leu Ile Met Phe Ser Leu Asn Leu His Met Arg 
            100                 105                 110         


Ile Pro Gln Ile Asn Trp Asn Leu Thr Asp Leu Val Asn Thr Gly Leu 
        115                 120                 125             


Ser Ala Phe Leu Phe Phe Ile Ala Ser Ile Val Leu Ala Ala Leu Asn 
    130                 135                 140                 


His Arg Ala Gly Ala Glu Ile Ala Ala Val Ile Phe Gly Phe Leu Ala 
145                 150                 155                 160 


Thr Ala Ala Tyr Ala Val Asn Thr Phe Leu Ala Val Gln Lys Trp Arg 
                165                 170                 175     


Val Ser Val Arg Gln Gln Ser Thr Asn Asp Tyr Ile Arg Ala Arg Thr 
            180                 185                 190         


Glu Ser Arg Asp Val Asp Ser Arg Pro Glu Ile Gln Arg Leu Asp Thr 
        195                 200                 205             


<210>  4209
<211>  582
<212>  PRT
<213>  homo sapiens

<400>  4209

Met Glu Ser Val Lys Gln Arg Ile Leu Ala Pro Gly Lys Glu Gly Leu 
1               5                   10                  15      


Lys Asn Phe Ala Gly Lys Ser Leu Gly Gln Ile Tyr Arg Val Leu Glu 
            20                  25                  30          


Lys Lys Gln Asp Thr Gly Glu Thr Ile Glu Leu Thr Glu Asp Gly Lys 
        35                  40                  45              


Pro Leu Glu Val Pro Glu Arg Lys Ala Pro Leu Cys Asp Cys Thr Cys 
    50                  55                  60                  


Phe Gly Leu Pro Arg Arg Tyr Ile Ile Ala Ile Met Ser Gly Leu Gly 
65                  70                  75                  80  


Phe Cys Ile Ser Phe Gly Ile Arg Cys Asn Leu Gly Val Ala Ile Val 
                85                  90                  95      


Asp Met Val Asn Asn Ser Thr Ile His Arg Gly Gly Lys Val Ile Lys 
            100                 105                 110         


Glu Lys Ala Lys Phe Asn Trp Asp Pro Glu Thr Val Gly Met Ile His 
        115                 120                 125             


Gly Ser Phe Phe Trp Gly Tyr Ile Ile Thr Gln Ile Pro Gly Gly Tyr 
    130                 135                 140                 


Ile Ala Ser Arg Leu Ala Ala Asn Arg Val Phe Gly Ala Ala Ile Leu 
145                 150                 155                 160 


Leu Thr Ser Thr Leu Asn Met Leu Ile Pro Ser Ala Ala Arg Val His 
                165                 170                 175     


Tyr Gly Cys Val Ile Phe Val Arg Ile Leu Gln Gly Leu Val Glu Gly 
            180                 185                 190         


Val Thr Tyr Pro Ala Cys His Gly Ile Trp Ser Lys Trp Ala Pro Pro 
        195                 200                 205             


Leu Glu Arg Ser Arg Leu Ala Thr Thr Ser Phe Cys Gly Ser Tyr Ala 
    210                 215                 220                 


Gly Ala Val Ile Ala Met Pro Leu Ala Gly Ile Leu Val Gln Tyr Thr 
225                 230                 235                 240 


Gly Trp Ser Ser Val Phe Tyr Val Tyr Gly Ser Phe Gly Met Val Trp 
                245                 250                 255     


Tyr Met Phe Trp Leu Leu Val Ser Tyr Glu Ser Pro Ala Lys His Pro 
            260                 265                 270         


Thr Ile Thr Asp Glu Glu Arg Arg Tyr Ile Glu Glu Ser Ile Gly Glu 
        275                 280                 285             


Ser Ala Asn Leu Leu Gly Ala Met Glu Lys Phe Lys Thr Pro Trp Arg 
    290                 295                 300                 


Lys Phe Phe Thr Ser Met Pro Val Tyr Ala Ile Ile Val Ala Asn Phe 
305                 310                 315                 320 


Cys Arg Ser Trp Thr Phe Tyr Leu Leu Leu Ile Ser Gln Pro Ala Tyr 
                325                 330                 335     


Phe Glu Glu Val Phe Gly Phe Glu Ile Ser Lys Val Gly Met Leu Ser 
            340                 345                 350         


Ala Val Pro His Leu Val Met Thr Ile Ile Val Pro Ile Gly Gly Gln 
        355                 360                 365             


Ile Ala Asp Phe Leu Arg Ser Lys Gln Ile Leu Ser Thr Thr Thr Val 
    370                 375                 380                 


Arg Lys Ile Met Asn Cys Gly Gly Phe Gly Met Glu Ala Thr Leu Leu 
385                 390                 395                 400 


Leu Val Val Gly Tyr Ser His Thr Arg Gly Val Ala Ile Ser Phe Leu 
                405                 410                 415     


Val Leu Ala Val Gly Phe Ser Gly Phe Ala Ile Ser Gly Phe Asn Val 
            420                 425                 430         


Asn His Leu Asp Ile Ala Pro Arg Tyr Ala Ser Ile Leu Met Gly Ile 
        435                 440                 445             


Ser Asn Gly Val Gly Thr Leu Ser Gly Met Val Cys Pro Ile Ile Val 
    450                 455                 460                 


Gly Ala Met Thr Lys Asn Lys Ser Arg Glu Glu Trp Gln Tyr Val Phe 
465                 470                 475                 480 


Leu Ile Ala Ala Leu Val His Tyr Gly Gly Val Ile Phe Tyr Ala Ile 
                485                 490                 495     


Phe Ala Ser Gly Glu Lys Gln Pro Trp Ala Asp Pro Glu Glu Thr Ser 
            500                 505                 510         


Glu Glu Lys Cys Gly Phe Ile His Glu Asp Glu Leu Asp Glu Glu Thr 
        515                 520                 525             


Gly Asp Ile Thr Gln Asn Tyr Ile Asn Tyr Gly Thr Thr Lys Ser Tyr 
    530                 535                 540                 


Gly Ala Thr Thr Gln Ala Asn Gly Gly Trp Pro Ser Gly Trp Glu Lys 
545                 550                 555                 560 


Lys Glu Glu Phe Val Gln Gly Glu Val Gln Asp Ser His Ser Tyr Lys 
                565                 570                 575     


Asp Arg Val Asp Tyr Ser 
            580         


<210>  4210
<211>  574
<212>  PRT
<213>  homo sapiens

<400>  4210

Met Ala Ser Thr Glu Gly Ala Asn Asn Met Pro Lys Gln Val Glu Val 
1               5                   10                  15      


Arg Met His Asp Ser His Leu Gly Ser Glu Glu Pro Lys His Arg His 
            20                  25                  30          


Leu Gly Leu Arg Leu Cys Asp Lys Leu Gly Lys Asn Leu Leu Leu Thr 
        35                  40                  45              


Leu Thr Val Phe Gly Val Ile Leu Gly Ala Val Cys Gly Gly Leu Leu 
    50                  55                  60                  


Arg Leu Ala Ser Pro Ile His Pro Asp Val Val Met Leu Ile Ala Phe 
65                  70                  75                  80  


Pro Gly Asp Ile Leu Met Arg Met Leu Lys Met Leu Ile Leu Pro Leu 
                85                  90                  95      


Ile Ile Ser Ser Leu Ile Thr Gly Leu Ser Gly Leu Asp Ala Lys Ala 
            100                 105                 110         


Ser Gly Arg Leu Gly Thr Arg Ala Met Val Tyr Tyr Met Ser Thr Thr 
        115                 120                 125             


Ile Ile Ala Ala Val Leu Gly Val Ile Leu Val Leu Ala Ile His Pro 
    130                 135                 140                 


Gly Asn Pro Lys Leu Lys Lys Gln Leu Gly Pro Gly Lys Lys Asn Asp 
145                 150                 155                 160 


Glu Val Ser Ser Leu Asp Ala Phe Leu Asp Leu Ile Arg Asn Leu Phe 
                165                 170                 175     


Pro Glu Asn Leu Val Gln Ala Cys Phe Gln Gln Ile Gln Thr Val Thr 
            180                 185                 190         


Lys Lys Val Leu Val Ala Pro Pro Pro Asp Glu Glu Ala Asn Ala Thr 
        195                 200                 205             


Ser Ala Val Val Ser Leu Leu Asn Glu Thr Val Thr Glu Val Pro Glu 
    210                 215                 220                 


Glu Thr Lys Met Val Ile Lys Lys Gly Leu Glu Phe Lys Asp Gly Met 
225                 230                 235                 240 


Asn Val Leu Gly Leu Ile Gly Phe Phe Ile Ala Phe Gly Ile Ala Met 
                245                 250                 255     


Gly Lys Met Gly Asp Gln Ala Lys Leu Met Val Asp Phe Phe Asn Ile 
            260                 265                 270         


Leu Asn Glu Ile Val Met Lys Leu Val Ile Met Ile Met Trp Tyr Ser 
        275                 280                 285             


Pro Leu Gly Ile Ala Cys Leu Ile Cys Gly Lys Ile Ile Ala Ile Lys 
    290                 295                 300                 


Asp Leu Glu Val Val Ala Arg Gln Leu Gly Met Tyr Met Val Thr Val 
305                 310                 315                 320 


Ile Ile Gly Leu Ile Ile His Gly Gly Ile Phe Leu Pro Leu Ile Tyr 
                325                 330                 335     


Phe Val Val Thr Arg Lys Asn Pro Phe Ser Phe Phe Ala Gly Ile Phe 
            340                 345                 350         


Gln Ala Trp Ile Thr Ala Leu Gly Thr Ala Ser Ser Ala Gly Thr Leu 
        355                 360                 365             


Pro Val Thr Phe Arg Cys Leu Glu Glu Asn Leu Gly Ile Asp Lys Arg 
    370                 375                 380                 


Val Thr Arg Phe Val Leu Pro Val Gly Ala Thr Ile Asn Met Asp Gly 
385                 390                 395                 400 


Thr Ala Leu Tyr Glu Ala Val Ala Ala Ile Phe Ile Ala Gln Met Asn 
                405                 410                 415     


Gly Val Val Leu Asp Gly Gly Gln Ile Val Thr Val Ser Leu Thr Ala 
            420                 425                 430         


Thr Leu Ala Ser Val Gly Ala Ala Ser Ile Pro Ser Ala Gly Leu Val 
        435                 440                 445             


Thr Met Leu Leu Ile Leu Thr Ala Val Gly Leu Pro Thr Glu Asp Ile 
    450                 455                 460                 


Ser Leu Leu Val Ala Val Asp Trp Leu Leu Asp Arg Met Arg Thr Ser 
465                 470                 475                 480 


Val Asn Val Val Gly Asp Ser Phe Gly Ala Gly Ile Val Tyr His Leu 
                485                 490                 495     


Ser Lys Ser Glu Leu Asp Thr Ile Asp Ser Gln His Arg Val His Glu 
            500                 505                 510         


Asp Ile Glu Met Thr Lys Thr Gln Ser Ile Tyr Asp Asp Met Lys Asn 
        515                 520                 525             


His Arg Glu Ser Asn Ser Asn Gln Cys Val Tyr Ala Ala His Asn Ser 
    530                 535                 540                 


Val Ile Val Asp Glu Cys Lys Val Thr Leu Ala Ala Asn Gly Lys Ser 
545                 550                 555                 560 


Ala Asp Cys Ser Val Glu Glu Glu Pro Trp Lys Arg Glu Lys 
                565                 570                 


<210>  4211
<211>  532
<212>  PRT
<213>  homo sapiens

<400>  4211

Met Glu Lys Ser Asn Glu Thr Asn Gly Tyr Leu Asp Ser Ala Gln Ala 
1               5                   10                  15      


Gly Pro Ala Ala Gly Pro Gly Ala Pro Gly Thr Ala Ala Gly Arg Ala 
            20                  25                  30          


Arg Arg Cys Ala Gly Phe Leu Arg Arg Gln Ala Leu Val Leu Leu Thr 
        35                  40                  45              


Val Ser Gly Val Leu Ala Gly Ala Gly Leu Gly Ala Ala Leu Arg Gly 
    50                  55                  60                  


Leu Ser Leu Ser Arg Thr Gln Val Thr Tyr Leu Ala Phe Pro Gly Glu 
65                  70                  75                  80  


Met Leu Leu Arg Met Leu Arg Met Ile Ile Leu Pro Leu Val Val Cys 
                85                  90                  95      


Ser Leu Val Ser Gly Ala Ala Ser Leu Asp Ala Ser Cys Leu Gly Arg 
            100                 105                 110         


Leu Gly Gly Ile Ala Val Ala Tyr Phe Gly Leu Thr Thr Leu Ser Ala 
        115                 120                 125             


Ser Ala Leu Ala Val Ala Leu Ala Phe Ile Ile Lys Pro Gly Ser Gly 
    130                 135                 140                 


Ala Gln Thr Leu Gln Ser Ser Asp Leu Gly Leu Glu Asp Ser Gly Pro 
145                 150                 155                 160 


Pro Pro Val Pro Lys Glu Thr Val Asp Ser Phe Leu Asp Leu Ala Arg 
                165                 170                 175     


Asn Leu Phe Pro Ser Asn Leu Val Val Ala Ala Phe Arg Thr Tyr Ala 
            180                 185                 190         


Thr Asp Tyr Lys Val Val Thr Gln Asn Ser Ser Ser Gly Asn Val Thr 
        195                 200                 205             


His Glu Lys Ile Pro Ile Gly Thr Glu Ile Glu Gly Met Asn Ile Leu 
    210                 215                 220                 


Gly Leu Val Leu Phe Ala Leu Val Leu Gly Val Ala Leu Lys Lys Leu 
225                 230                 235                 240 


Gly Ser Glu Gly Glu Asp Leu Ile Arg Phe Phe Asn Ser Leu Asn Glu 
                245                 250                 255     


Ala Thr Met Val Leu Val Ser Trp Ile Met Trp Tyr Val Pro Val Gly 
            260                 265                 270         


Ile Met Phe Leu Val Gly Ser Lys Ile Val Glu Met Lys Asp Ile Ile 
        275                 280                 285             


Val Leu Val Thr Ser Leu Gly Lys Tyr Ile Phe Ala Ser Ile Leu Gly 
    290                 295                 300                 


His Val Ile His Gly Gly Ile Val Leu Pro Leu Ile Tyr Phe Val Phe 
305                 310                 315                 320 


Thr Arg Lys Asn Pro Phe Arg Phe Leu Leu Gly Leu Leu Ala Pro Phe 
                325                 330                 335     


Ala Thr Ala Phe Ala Thr Cys Ser Ser Ser Ala Thr Leu Pro Ser Met 
            340                 345                 350         


Met Lys Cys Ile Glu Glu Asn Asn Gly Val Asp Lys Arg Ile Ser Arg 
        355                 360                 365             


Phe Ile Leu Pro Ile Gly Ala Thr Val Asn Met Asp Gly Ala Ala Ile 
    370                 375                 380                 


Phe Gln Cys Val Ala Ala Val Phe Ile Ala Gln Leu Asn Asn Val Glu 
385                 390                 395                 400 


Leu Asn Ala Gly Gln Ile Phe Thr Ile Leu Val Thr Ala Thr Ala Ser 
                405                 410                 415     


Ser Val Gly Ala Ala Gly Val Pro Ala Gly Gly Val Leu Thr Ile Ala 
            420                 425                 430         


Ile Ile Leu Glu Ala Ile Gly Leu Pro Thr His Asp Leu Pro Leu Ile 
        435                 440                 445             


Leu Ala Val Asp Trp Ile Val Asp Arg Thr Thr Thr Val Val Asn Val 
    450                 455                 460                 


Glu Gly Asp Ala Leu Gly Ala Gly Ile Leu His His Leu Asn Gln Lys 
465                 470                 475                 480 


Ala Thr Lys Lys Gly Glu Gln Glu Leu Ala Glu Val Lys Val Glu Ala 
                485                 490                 495     


Ile Pro Asn Cys Lys Ser Glu Glu Glu Thr Ser Pro Leu Val Thr His 
            500                 505                 510         


Gln Asn Pro Ala Gly Pro Val Ala Ser Ala Pro Glu Leu Glu Ser Lys 
        515                 520                 525             


Glu Ser Val Leu 
    530         


<210>  4212
<211>  283
<212>  PRT
<213>  homo sapiens

<400>  4212

Met Ala Gly Asn Phe Trp Gln Ser Ser His Tyr Leu Gln Trp Ile Leu 
1               5                   10                  15      


Asp Lys Gln Asp Leu Leu Lys Glu Arg Gln Lys Asp Leu Lys Phe Leu 
            20                  25                  30          


Ser Glu Glu Glu Tyr Trp Lys Leu Gln Ile Phe Phe Thr Asn Val Ile 
        35                  40                  45              


Gln Ala Leu Gly Glu His Leu Lys Leu Arg Gln Gln Val Ile Ala Thr 
    50                  55                  60                  


Ala Thr Val Tyr Phe Lys Arg Phe Tyr Ala Arg Tyr Ser Leu Lys Ser 
65                  70                  75                  80  


Ile Asp Pro Val Leu Met Ala Pro Thr Cys Val Phe Leu Ala Ser Lys 
                85                  90                  95      


Val Glu Glu Phe Gly Val Val Ser Asn Thr Arg Leu Ile Ala Ala Ala 
            100                 105                 110         


Thr Ser Val Leu Lys Thr Arg Phe Ser Tyr Ala Phe Pro Lys Glu Phe 
        115                 120                 125             


Pro Tyr Arg Met Asn His Ile Leu Glu Cys Glu Phe Tyr Leu Leu Glu 
    130                 135                 140                 


Leu Met Asp Cys Cys Leu Ile Val Tyr His Pro Tyr Arg Pro Leu Leu 
145                 150                 155                 160 


Gln Tyr Val Gln Asp Met Gly Gln Glu Asp Met Leu Leu Pro Leu Ala 
                165                 170                 175     


Trp Arg Ile Val Asn Asp Thr Tyr Arg Thr Asp Leu Cys Leu Leu Tyr 
            180                 185                 190         


Pro Pro Phe Met Ile Ala Leu Ala Cys Leu His Val Ala Cys Val Val 
        195                 200                 205             


Gln Gln Lys Asp Ala Arg Gln Trp Phe Ala Glu Leu Ser Val Asp Met 
    210                 215                 220                 


Glu Lys Ile Leu Glu Ile Ile Arg Val Ile Leu Lys Leu Tyr Glu Gln 
225                 230                 235                 240 


Trp Lys Asn Phe Asp Glu Arg Lys Glu Met Ala Thr Ile Leu Ser Lys 
                245                 250                 255     


Met Pro Lys Pro Lys Pro Pro Pro Asn Ser Glu Gly Glu Gln Gly Pro 
            260                 265                 270         


Asn Gly Ser Gln Asn Ser Ser Tyr Ser Gln Ser 
        275                 280             


<210>  4213
<211>  1268
<212>  PRT
<213>  homo sapiens

<400>  4213

Met Asp Gln Lys Ile Leu Ser Leu Ala Ala Glu Lys Thr Ala Asp Lys 
1               5                   10                  15      


Leu Gln Glu Phe Leu Gln Thr Leu Arg Glu Gly Asp Leu Thr Asn Leu 
            20                  25                  30          


Leu Gln Asn Gln Ala Val Lys Gly Lys Val Ala Gly Ala Leu Leu Arg 
        35                  40                  45              


Ala Ile Phe Lys Gly Ser Pro Cys Ser Glu Glu Ala Gly Thr Leu Arg 
    50                  55                  60                  


Arg Arg Lys Ile Tyr Thr Cys Cys Ile Gln Leu Val Glu Ser Gly Asp 
65                  70                  75                  80  


Leu Gln Lys Glu Ile Ala Ser Glu Ile Ile Gly Leu Leu Met Leu Glu 
                85                  90                  95      


Ala His His Phe Pro Gly Pro Leu Leu Val Glu Leu Ala Asn Glu Phe 
            100                 105                 110         


Ile Ser Ala Val Arg Glu Gly Ser Leu Val Asn Gly Lys Ser Leu Glu 
        115                 120                 125             


Leu Leu Pro Ile Ile Leu Thr Ala Leu Ala Thr Lys Lys Glu Asn Leu 
    130                 135                 140                 


Ala Tyr Gly Lys Gly Val Leu Ser Gly Glu Glu Cys Lys Lys Gln Leu 
145                 150                 155                 160 


Ile Asn Thr Leu Cys Ser Gly Arg Trp Asp Gln Gln Tyr Val Ile Gln 
                165                 170                 175     


Leu Thr Ser Met Phe Lys Asp Val Pro Leu Thr Ala Glu Glu Val Glu 
            180                 185                 190         


Phe Val Val Glu Lys Ala Leu Ser Met Phe Ser Lys Met Asn Leu Gln 
        195                 200                 205             


Glu Ile Pro Pro Leu Val Tyr Gln Leu Leu Val Leu Ser Ser Lys Gly 
    210                 215                 220                 


Ser Arg Lys Ser Val Leu Glu Gly Ile Ile Ala Phe Phe Ser Ala Leu 
225                 230                 235                 240 


Asp Lys Gln His Asn Glu Glu Gln Ser Gly Asp Glu Leu Leu Asp Val 
                245                 250                 255     


Val Thr Val Pro Ser Gly Glu Leu Arg His Val Glu Gly Thr Ile Ile 
            260                 265                 270         


Leu His Ile Val Phe Ala Ile Lys Leu Asp Tyr Glu Leu Gly Arg Glu 
        275                 280                 285             


Leu Val Lys His Leu Lys Val Gly Gln Gln Gly Asp Ser Asn Asn Asn 
    290                 295                 300                 


Leu Ser Pro Phe Ser Ile Ala Leu Leu Leu Ser Val Thr Arg Ile Gln 
305                 310                 315                 320 


Arg Phe Gln Asp Gln Val Leu Asp Leu Leu Lys Thr Ser Val Val Lys 
                325                 330                 335     


Ser Phe Lys Asp Leu Gln Leu Leu Gln Gly Ser Lys Phe Leu Gln Asn 
            340                 345                 350         


Leu Val Pro His Arg Ser Tyr Val Ser Thr Met Ile Leu Glu Val Val 
        355                 360                 365             


Lys Asn Ser Val His Ser Trp Asp His Val Thr Gln Gly Leu Val Glu 
    370                 375                 380                 


Leu Gly Phe Ile Leu Met Asp Ser Tyr Gly Pro Lys Lys Val Leu Asp 
385                 390                 395                 400 


Gly Lys Thr Ile Glu Thr Ser Pro Ser Leu Ser Arg Met Pro Asn Gln 
                405                 410                 415     


His Ala Cys Lys Leu Gly Ala Asn Ile Leu Leu Glu Thr Phe Lys Ile 
            420                 425                 430         


His Glu Met Ile Arg Gln Glu Ile Leu Glu Gln Val Leu Asn Arg Val 
        435                 440                 445             


Val Thr Arg Ala Ser Ser Pro Ile Ser His Phe Leu Asp Leu Leu Ser 
    450                 455                 460                 


Asn Ile Val Met Tyr Ala Pro Leu Val Leu Gln Ser Cys Ser Ser Lys 
465                 470                 475                 480 


Val Thr Glu Ala Phe Asp Tyr Leu Ser Phe Leu Pro Leu Gln Thr Val 
                485                 490                 495     


Gln Arg Leu Leu Lys Ala Val Gln Pro Leu Leu Lys Val Ser Met Ser 
            500                 505                 510         


Met Arg Asp Cys Leu Ile Leu Val Leu Arg Lys Ala Met Phe Ala Asn 
        515                 520                 525             


Gln Leu Asp Ala Arg Lys Ser Ala Val Ala Gly Phe Leu Leu Leu Leu 
    530                 535                 540                 


Lys Asn Phe Lys Val Leu Gly Ser Leu Ser Ser Ser Gln Cys Ser Gln 
545                 550                 555                 560 


Ser Leu Ser Val Ser Gln Val His Val Asp Val His Ser His Tyr Asn 
                565                 570                 575     


Ser Val Ala Asn Glu Thr Phe Cys Leu Glu Ile Met Asp Ser Leu Arg 
            580                 585                 590         


Arg Cys Leu Ser Gln Gln Ala Asp Val Arg Leu Met Leu Tyr Glu Gly 
        595                 600                 605             


Phe Tyr Asp Val Leu Arg Arg Asn Ser Gln Leu Ala Asn Ser Val Met 
    610                 615                 620                 


Gln Thr Leu Leu Ser Gln Leu Lys Gln Phe Tyr Glu Pro Lys Pro Asp 
625                 630                 635                 640 


Leu Leu Pro Pro Leu Lys Leu Glu Ala Cys Ile Leu Thr Gln Gly Asp 
                645                 650                 655     


Lys Ile Ser Leu Gln Glu Pro Leu Asp Tyr Leu Leu Cys Cys Ile Gln 
            660                 665                 670         


His Cys Leu Ala Trp Tyr Lys Asn Thr Val Ile Pro Leu Gln Gln Gly 
        675                 680                 685             


Glu Glu Glu Glu Glu Glu Glu Glu Ala Phe Tyr Glu Asp Leu Asp Asp 
    690                 695                 700                 


Ile Leu Glu Ser Ile Thr Asn Arg Met Ile Lys Ser Glu Leu Glu Asp 
705                 710                 715                 720 


Phe Glu Leu Asp Lys Ser Ala Asp Phe Ser Gln Ser Thr Ser Ile Gly 
                725                 730                 735     


Ile Lys Asn Asn Ile Cys Ala Phe Leu Val Met Gly Val Cys Glu Val 
            740                 745                 750         


Leu Ile Glu Tyr Asn Phe Ser Ile Ser Ser Phe Ser Lys Asn Arg Phe 
        755                 760                 765             


Glu Asp Ile Leu Ser Leu Phe Met Cys Tyr Lys Lys Leu Ser Asp Ile 
    770                 775                 780                 


Leu Asn Glu Lys Ala Gly Lys Ala Lys Thr Lys Met Ala Asn Lys Thr 
785                 790                 795                 800 


Ser Asp Ser Leu Leu Ser Met Lys Phe Val Ser Ser Leu Leu Thr Ala 
                805                 810                 815     


Leu Phe Arg Val Leu Leu Trp Arg Tyr Thr Ser Ile Pro Thr Ser Val 
            820                 825                 830         


Glu Glu Ser Gly Lys Lys Glu Lys Gly Lys Ser Ile Ser Leu Leu Cys 
        835                 840                 845             


Leu Glu Gly Leu Gln Lys Ile Phe Ser Ala Val Gln Gln Phe Tyr Gln 
    850                 855                 860                 


Pro Lys Ile Gln Gln Phe Leu Arg Ala Leu Asp Val Thr Asp Lys Glu 
865                 870                 875                 880 


Gly Glu Glu Arg Glu Asp Ala Asp Val Ser Val Thr Gln Arg Thr Ala 
                885                 890                 895     


Phe Gln Ile Arg Gln Phe Gln Arg Ser Leu Leu Asn Leu Leu Ser Ser 
            900                 905                 910         


Gln Glu Glu Asp Phe Asn Ser Lys Glu Ala Leu Leu Leu Val Thr Val 
        915                 920                 925             


Leu Thr Ser Leu Ser Lys Leu Leu Glu Pro Ser Ser Pro Gln Phe Val 
    930                 935                 940                 


Gln Met Leu Ser Trp Thr Ser Lys Ile Cys Lys Glu Asn Ser Arg Glu 
945                 950                 955                 960 


Asp Ala Leu Phe Cys Lys Ser Leu Met Asn Leu Leu Phe Ser Leu His 
                965                 970                 975     


Val Ser Tyr Lys Ser Pro Val Ile Leu Leu Arg Asp Leu Ser Gln Asp 
            980                 985                 990         


Ile His Gly His Leu Gly Asp Ile  Asp Gln Asp Val Glu  Val Glu Lys 
        995                 1000                 1005             


Thr Asn  His Phe Ala Ile Val  Asn Leu Arg Thr Ala  Ala Pro Thr 
    1010                 1015                 1020             


Val Cys  Leu Leu Val Leu Ser  Gln Ala Glu Lys Val  Leu Glu Glu 
    1025                 1030                 1035             


Val Asp  Trp Leu Ile Thr Lys  Leu Lys Gly Gln Val  Ser Gln Glu 
    1040                 1045                 1050             


Thr Leu  Ser Glu Glu Ala Ser  Ser Gln Ala Thr Leu  Pro Asn Gln 
    1055                 1060                 1065             


Pro Val  Glu Lys Ala Ile Ile  Met Gln Leu Gly Thr  Leu Leu Thr 
    1070                 1075                 1080             


Phe Phe  His Glu Leu Val Gln  Thr Ala Leu Pro Ser  Gly Ser Cys 
    1085                 1090                 1095             


Val Asp  Thr Leu Leu Lys Asp  Leu Cys Lys Met Tyr  Thr Thr Leu 
    1100                 1105                 1110             


Thr Ala  Leu Val Arg Tyr Tyr  Leu Gln Val Cys Gln  Ser Ser Gly 
    1115                 1120                 1125             


Gly Ile  Pro Lys Asn Met Glu  Lys Leu Val Lys Leu  Ser Gly Ser 
    1130                 1135                 1140             


His Leu  Thr Pro Leu Cys Tyr  Ser Phe Ile Ser Tyr  Val Gln Asn 
    1145                 1150                 1155             


Lys Ser  Lys Ser Leu Asn Tyr  Thr Gly Glu Lys Lys  Glu Lys Pro 
    1160                 1165                 1170             


Ala Ala  Val Ala Thr Ala Met  Ala Arg Val Leu Arg  Glu Thr Lys 
    1175                 1180                 1185             


Pro Ile  Pro Asn Leu Ile Phe  Ala Ile Glu Gln Tyr  Glu Lys Phe 
    1190                 1195                 1200             


Leu Ile  His Leu Ser Lys Lys  Ser Lys Val Asn Leu  Met Gln His 
    1205                 1210                 1215             


Met Lys  Leu Ser Thr Ser Arg  Asp Phe Lys Ile Lys  Gly Asn Ile 
    1220                 1225                 1230             


Leu Asp  Met Val Leu Arg Glu  Asp Gly Glu Asp Glu  Asn Glu Glu 
    1235                 1240                 1245             


Gly Thr  Ala Ser Glu His Gly  Gly Gln Asn Lys Glu  Pro Ala Lys 
    1250                 1255                 1260             


Lys Lys  Arg Lys Lys 
    1265             


<210>  4214
<211>  329
<212>  PRT
<213>  homo sapiens

<400>  4214

Met Val Arg Thr Lys Thr Trp Thr Leu Lys Lys His Phe Val Gly Tyr 
1               5                   10                  15      


Pro Thr Asn Ser Asp Phe Glu Leu Lys Thr Ala Glu Leu Pro Pro Leu 
            20                  25                  30          


Lys Asn Gly Glu Val Leu Leu Glu Ala Leu Phe Leu Thr Val Asp Pro 
        35                  40                  45              


Tyr Met Arg Val Ala Ala Lys Arg Leu Lys Glu Gly Asp Thr Met Met 
    50                  55                  60                  


Gly Gln Gln Val Ala Lys Val Val Glu Ser Lys Asn Val Ala Leu Pro 
65                  70                  75                  80  


Lys Gly Thr Ile Val Leu Ala Ser Pro Gly Trp Thr Thr His Ser Ile 
                85                  90                  95      


Ser Asp Gly Lys Asp Leu Glu Lys Leu Leu Thr Glu Trp Pro Asp Thr 
            100                 105                 110         


Ile Pro Leu Ser Leu Ala Leu Gly Thr Val Gly Met Pro Gly Leu Thr 
        115                 120                 125             


Ala Tyr Phe Gly Leu Leu Glu Ile Cys Gly Val Lys Gly Gly Glu Thr 
    130                 135                 140                 


Val Met Val Asn Ala Ala Ala Gly Ala Val Gly Ser Val Val Gly Gln 
145                 150                 155                 160 


Ile Ala Lys Leu Lys Gly Cys Lys Val Val Gly Ala Val Gly Ser Asp 
                165                 170                 175     


Glu Lys Val Ala Tyr Leu Gln Lys Leu Gly Phe Asp Val Val Phe Asn 
            180                 185                 190         


Tyr Lys Thr Val Glu Ser Leu Glu Glu Thr Leu Lys Lys Ala Ser Pro 
        195                 200                 205             


Asp Gly Tyr Asp Cys Tyr Phe Asp Asn Val Gly Gly Glu Phe Ser Asn 
    210                 215                 220                 


Thr Val Ile Gly Gln Met Lys Lys Phe Gly Arg Ile Ala Ile Cys Gly 
225                 230                 235                 240 


Ala Ile Ser Thr Tyr Asn Arg Thr Gly Pro Leu Pro Pro Gly Pro Pro 
                245                 250                 255     


Pro Glu Ile Val Ile Tyr Gln Glu Leu Arg Met Glu Ala Phe Val Val 
            260                 265                 270         


Tyr Arg Trp Gln Gly Asp Ala Arg Gln Lys Ala Leu Lys Asp Leu Leu 
        275                 280                 285             


Lys Trp Val Leu Glu Gly Lys Ile Gln Tyr Lys Glu Tyr Ile Ile Glu 
    290                 295                 300                 


Gly Phe Glu Asn Met Pro Ala Ala Phe Met Gly Met Leu Lys Gly Asp 
305                 310                 315                 320 


Asn Leu Gly Lys Thr Ile Val Lys Ala 
                325                 


<210>  4215
<211>  405
<212>  PRT
<213>  homo sapiens

<400>  4215

Met Phe Ser Thr Leu Arg Phe Phe Glu Gly Phe Cys Leu Ala Gly Ile 
1               5                   10                  15      


Ile Leu Thr Leu Tyr Ala Leu Arg Ile Glu Leu Cys Pro Pro Gly Lys 
            20                  25                  30          


Arg Phe Met Ile Thr Met Val Ala Ser Phe Val Ala Met Ala Gly Gln 
        35                  40                  45              


Phe Leu Met Pro Gly Leu Ala Ala Leu Cys Arg Asp Trp Gln Val Leu 
    50                  55                  60                  


Gln Ala Leu Ile Ile Cys Pro Phe Leu Leu Met Leu Leu Tyr Trp Ser 
65                  70                  75                  80  


Ile Phe Pro Glu Ser Leu Arg Trp Leu Met Ala Thr Gln Gln Phe Glu 
                85                  90                  95      


Ser Ala Lys Arg Leu Ile Leu His Phe Thr Gln Lys Asn Arg Met Asn 
            100                 105                 110         


Pro Glu Gly Asp Ile Lys Gly Val Ile Pro Glu Leu Glu Lys Glu Leu 
        115                 120                 125             


Ser Arg Arg Pro Lys Lys Val Cys Ile Val Lys Val Val Gly Thr Arg 
    130                 135                 140                 


Asn Leu Trp Lys Asn Ile Val Val Leu Cys Val Asn Ser Leu Thr Gly 
145                 150                 155                 160 


Tyr Gly Ile His His Cys Phe Ala Arg Ser Met Met Gly His Glu Val 
                165                 170                 175     


Lys Val Pro Leu Leu Glu Asn Phe Tyr Ala Asp Tyr Tyr Thr Thr Ala 
            180                 185                 190         


Ser Ile Ala Leu Val Ser Cys Leu Ala Met Cys Val Val Val Arg Phe 
        195                 200                 205             


Leu Gly Arg Arg Gly Gly Leu Leu Leu Phe Met Ile Leu Thr Ala Leu 
    210                 215                 220                 


Ala Ser Leu Leu Gln Leu Gly Leu Leu Asn Leu Ile Gly Lys Tyr Ser 
225                 230                 235                 240 


Gln His Pro Asp Ser Gly Met Ser Asp Ser Val Lys Asp Lys Phe Ser 
                245                 250                 255     


Ile Ala Phe Ser Ile Val Gly Met Phe Ala Ser His Ala Val Gly Ser 
            260                 265                 270         


Leu Ser Val Phe Phe Cys Ala Glu Ile Thr Pro Thr Val Ile Arg Cys 
        275                 280                 285             


Gly Gly Leu Gly Leu Val Leu Ala Ser Ala Gly Phe Gly Met Leu Thr 
    290                 295                 300                 


Ala Pro Ile Ile Glu Leu His Asn Gln Lys Gly Tyr Phe Leu His His 
305                 310                 315                 320 


Ile Ile Phe Ala Cys Cys Thr Leu Ile Cys Ile Ile Cys Ile Leu Leu 
                325                 330                 335     


Leu Pro Glu Ser Arg Asp Gln Asn Leu Pro Glu Asn Ile Ser Asn Gly 
            340                 345                 350         


Glu His Tyr Thr Arg Gln Pro Leu Leu Pro His Lys Lys Gly Glu Gln 
        355                 360                 365             


Pro Leu Leu Leu Thr Asn Ala Glu Leu Lys Asp Tyr Ser Gly Leu His 
    370                 375                 380                 


Asp Ala Ala Ala Ala Gly Asp Thr Leu Pro Glu Gly Ala Thr Ala Asn 
385                 390                 395                 400 


Gly Met Lys Ala Met 
                405 


<210>  4216
<211>  686
<212>  PRT
<213>  homo sapiens

<400>  4216

Met Ala Ile Asp Arg Arg Arg Glu Ala Ala Gly Gly Gly Pro Gly Arg 
1               5                   10                  15      


Gln Pro Ala Pro Ala Glu Glu Asn Gly Ser Leu Pro Pro Gly Asp Ala 
            20                  25                  30          


Ala Ala Ser Ala Pro Leu Gly Gly Arg Ala Gly Pro Gly Gly Gly Ala 
        35                  40                  45              


Glu Ile Gln Pro Leu Pro Pro Leu His Pro Gly Gly Gly Pro His Pro 
    50                  55                  60                  


Ser Cys Cys Ser Ala Ala Ala Ala Pro Ser Leu Leu Leu Leu Asp Tyr 
65                  70                  75                  80  


Asp Gly Ser Val Leu Pro Phe Leu Gly Gly Leu Gly Gly Gly Tyr Gln 
                85                  90                  95      


Lys Thr Leu Val Leu Leu Thr Trp Ile Pro Ala Leu Phe Ile Gly Phe 
            100                 105                 110         


Ser Gln Phe Ser Asp Ser Phe Leu Leu Asp Gln Pro Asn Phe Trp Cys 
        115                 120                 125             


Arg Gly Ala Gly Lys Gly Thr Glu Leu Ala Gly Val Thr Thr Thr Gly 
    130                 135                 140                 


Arg Gly Gly Asp Met Gly Asn Trp Thr Ser Leu Pro Thr Thr Pro Phe 
145                 150                 155                 160 


Ala Thr Ala Pro Trp Glu Ala Ala Gly Asn Arg Ser Asn Ser Ser Gly 
                165                 170                 175     


Ala Asp Gly Gly Asp Thr Pro Pro Leu Pro Ser Pro Pro Asp Lys Gly 
            180                 185                 190         


Asp Asn Ala Ser Asn Cys Asp Cys Arg Ala Trp Asp Tyr Gly Ile Arg 
        195                 200                 205             


Ala Gly Leu Val Gln Asn Val Val Ser Lys Trp Asp Leu Val Cys Asp 
    210                 215                 220                 


Asn Ala Trp Lys Val His Ile Ala Lys Phe Ser Leu Leu Val Gly Leu 
225                 230                 235                 240 


Ile Phe Gly Tyr Leu Ile Thr Gly Cys Ile Ala Asp Trp Val Gly Arg 
                245                 250                 255     


Arg Pro Val Leu Leu Phe Ser Ile Ile Phe Ile Leu Ile Phe Gly Leu 
            260                 265                 270         


Thr Val Ala Leu Ser Val Asn Val Thr Met Phe Ser Thr Leu Arg Phe 
        275                 280                 285             


Phe Glu Gly Phe Cys Leu Ala Gly Ile Ile Leu Thr Leu Tyr Ala Leu 
    290                 295                 300                 


Arg Ile Glu Leu Cys Pro Pro Gly Lys Arg Phe Met Ile Thr Met Val 
305                 310                 315                 320 


Ala Ser Phe Val Ala Met Ala Gly Gln Phe Leu Met Pro Gly Leu Ala 
                325                 330                 335     


Ala Leu Cys Arg Asp Trp Gln Val Leu Gln Ala Leu Ile Ile Cys Pro 
            340                 345                 350         


Phe Leu Leu Met Leu Leu Tyr Trp Ser Ile Phe Pro Glu Ser Leu Arg 
        355                 360                 365             


Trp Leu Met Ala Thr Gln Gln Phe Glu Ser Ala Lys Arg Leu Ile Leu 
    370                 375                 380                 


His Phe Thr Gln Lys Asn Arg Met Asn Pro Glu Gly Asp Ile Lys Gly 
385                 390                 395                 400 


Val Ile Pro Glu Leu Glu Lys Glu Leu Ser Arg Arg Pro Lys Lys Val 
                405                 410                 415     


Cys Ile Val Lys Val Val Gly Thr Arg Asn Leu Trp Lys Asn Ile Val 
            420                 425                 430         


Val Leu Cys Val Asn Ser Leu Thr Gly Tyr Gly Ile His His Cys Phe 
        435                 440                 445             


Ala Arg Ser Met Met Gly His Glu Val Lys Val Pro Leu Leu Glu Asn 
    450                 455                 460                 


Phe Tyr Ala Asp Tyr Tyr Thr Thr Ala Ser Ile Ala Leu Val Ser Cys 
465                 470                 475                 480 


Leu Ala Met Cys Val Val Val Arg Phe Leu Gly Arg Arg Gly Gly Leu 
                485                 490                 495     


Leu Leu Phe Met Ile Leu Thr Ala Leu Ala Ser Leu Leu Gln Leu Gly 
            500                 505                 510         


Leu Leu Asn Leu Ile Gly Lys Tyr Ser Gln His Pro Asp Ser Gly Met 
        515                 520                 525             


Ser Asp Ser Val Lys Asp Lys Phe Ser Ile Ala Phe Ser Ile Val Gly 
    530                 535                 540                 


Met Phe Ala Ser His Ala Val Gly Ser Leu Ser Val Phe Phe Cys Ala 
545                 550                 555                 560 


Glu Ile Thr Pro Thr Val Ile Arg Cys Gly Gly Leu Gly Leu Val Leu 
                565                 570                 575     


Ala Ser Ala Gly Phe Gly Met Leu Thr Ala Pro Ile Ile Glu Leu His 
            580                 585                 590         


Asn Gln Lys Gly Tyr Phe Leu His His Ile Ile Phe Ala Cys Cys Thr 
        595                 600                 605             


Leu Ile Cys Ile Ile Cys Ile Leu Leu Leu Pro Glu Ser Arg Asp Gln 
    610                 615                 620                 


Asn Leu Pro Glu Asn Ile Ser Asn Gly Glu His Tyr Thr Arg Gln Pro 
625                 630                 635                 640 


Leu Leu Pro His Lys Lys Gly Glu Gln Pro Leu Leu Leu Thr Asn Ala 
                645                 650                 655     


Glu Leu Lys Asp Tyr Ser Gly Leu His Asp Ala Ala Ala Ala Gly Asp 
            660                 665                 670         


Thr Leu Pro Glu Gly Ala Thr Ala Asn Gly Met Lys Ala Met 
        675                 680                 685     


<210>  4217
<211>  321
<212>  PRT
<213>  homo sapiens

<400>  4217

Met Ala Thr Gly Gly Gln Gln Lys Glu Asn Thr Leu Leu His Leu Phe 
1               5                   10                  15      


Ala Gly Gly Cys Gly Gly Thr Val Gly Ala Ile Phe Thr Cys Pro Leu 
            20                  25                  30          


Glu Val Ile Lys Thr Arg Leu Gln Ser Ser Arg Leu Ala Leu Arg Thr 
        35                  40                  45              


Val Tyr Tyr Pro Gln Val His Leu Gly Thr Ile Ser Gly Ala Gly Met 
    50                  55                  60                  


Val Arg Pro Thr Ser Val Thr Pro Gly Leu Phe Gln Val Leu Lys Ser 
65                  70                  75                  80  


Ile Leu Glu Lys Glu Gly Pro Lys Ser Leu Phe Arg Gly Leu Gly Pro 
                85                  90                  95      


Asn Leu Val Gly Val Ala Pro Ser Arg Ala Val Tyr Phe Ala Cys Tyr 
            100                 105                 110         


Ser Lys Ala Lys Glu Gln Phe Asn Gly Ile Phe Val Pro Asn Ser Asn 
        115                 120                 125             


Ile Val His Ile Phe Ser Ala Gly Ser Ala Ala Phe Ile Thr Asn Ser 
    130                 135                 140                 


Leu Met Asn Pro Ile Trp Met Val Lys Thr Arg Met Gln Leu Glu Gln 
145                 150                 155                 160 


Lys Val Arg Gly Ser Lys Gln Met Asn Thr Leu Gln Cys Ala Arg Tyr 
                165                 170                 175     


Val Tyr Gln Thr Glu Gly Ile Arg Gly Phe Tyr Arg Gly Leu Thr Ala 
            180                 185                 190         


Ser Tyr Ala Gly Ile Ser Glu Thr Ile Ile Cys Phe Ala Ile Tyr Glu 
        195                 200                 205             


Ser Leu Lys Lys Tyr Leu Lys Glu Ala Pro Leu Ala Ser Ser Ala Asn 
    210                 215                 220                 


Gly Thr Glu Lys Asn Ser Thr Ser Phe Phe Gly Leu Met Ala Ala Ala 
225                 230                 235                 240 


Ala Leu Ser Lys Gly Cys Ala Ser Cys Ile Ala Tyr Pro His Glu Val 
                245                 250                 255     


Ile Arg Thr Arg Leu Arg Glu Glu Gly Thr Lys Tyr Lys Ser Phe Val 
            260                 265                 270         


Gln Thr Ala Arg Leu Val Phe Arg Glu Glu Gly Tyr Leu Ala Phe Tyr 
        275                 280                 285             


Arg Gly Leu Phe Ala Gln Leu Ile Arg Gln Ile Pro Asn Thr Ala Ile 
    290                 295                 300                 


Val Leu Ser Thr Tyr Glu Leu Ile Val Tyr Leu Leu Glu Asp Arg Thr 
305                 310                 315                 320 


Gln 
    


<210>  4218
<211>  599
<212>  PRT
<213>  homo sapiens

<400>  4218

Met Ala Thr Asn Gly Ser Lys Val Ala Asp Gly Gln Ile Ser Thr Glu 
1               5                   10                  15      


Val Ser Glu Ala Pro Val Ala Asn Asp Lys Pro Lys Thr Leu Val Val 
            20                  25                  30          


Lys Val Gln Lys Lys Ala Ala Asp Leu Pro Asp Arg Asp Thr Trp Lys 
        35                  40                  45              


Gly Arg Phe Asp Phe Leu Met Ser Cys Val Gly Tyr Ala Ile Gly Leu 
    50                  55                  60                  


Gly Asn Val Trp Arg Phe Pro Tyr Leu Cys Gly Lys Asn Gly Gly Gly 
65                  70                  75                  80  


Ala Phe Leu Ile Pro Tyr Phe Leu Thr Leu Ile Phe Ala Gly Val Pro 
                85                  90                  95      


Leu Phe Leu Leu Glu Cys Ser Leu Gly Gln Tyr Thr Ser Ile Gly Gly 
            100                 105                 110         


Leu Gly Val Trp Lys Leu Ala Pro Met Phe Lys Gly Val Gly Leu Ala 
        115                 120                 125             


Ala Ala Val Leu Ser Phe Trp Leu Asn Ile Tyr Tyr Ile Val Ile Ile 
    130                 135                 140                 


Ser Trp Ala Ile Tyr Tyr Leu Tyr Asn Ser Phe Thr Thr Thr Leu Pro 
145                 150                 155                 160 


Trp Lys Gln Cys Asp Asn Pro Trp Asn Thr Asp Arg Cys Phe Ser Asn 
                165                 170                 175     


Tyr Ser Met Val Asn Thr Thr Asn Met Thr Ser Ala Val Val Glu Phe 
            180                 185                 190         


Trp Glu Arg Asn Met His Gln Met Thr Asp Gly Leu Asp Lys Pro Gly 
        195                 200                 205             


Gln Ile Arg Trp Pro Leu Ala Ile Thr Leu Ala Ile Ala Trp Ile Leu 
    210                 215                 220                 


Val Tyr Phe Cys Ile Trp Lys Gly Val Gly Trp Thr Gly Lys Val Val 
225                 230                 235                 240 


Tyr Phe Ser Ala Thr Tyr Pro Tyr Ile Met Leu Ile Ile Leu Phe Phe 
                245                 250                 255     


Arg Gly Val Thr Leu Pro Gly Ala Lys Glu Gly Ile Leu Phe Tyr Ile 
            260                 265                 270         


Thr Pro Asn Phe Arg Lys Leu Ser Asp Ser Glu Val Trp Leu Asp Ala 
        275                 280                 285             


Ala Thr Gln Ile Phe Phe Ser Tyr Gly Leu Gly Leu Gly Ser Leu Ile 
    290                 295                 300                 


Ala Leu Gly Ser Tyr Asn Ser Phe His Asn Asn Val Tyr Arg Asp Ser 
305                 310                 315                 320 


Ile Ile Val Cys Cys Ile Asn Ser Cys Thr Ser Met Phe Ala Gly Phe 
                325                 330                 335     


Val Ile Phe Ser Ile Val Gly Phe Met Ala His Val Thr Lys Arg Ser 
            340                 345                 350         


Ile Ala Asp Val Ala Ala Ser Gly Pro Gly Leu Ala Phe Leu Ala Tyr 
        355                 360                 365             


Pro Glu Ala Val Thr Gln Leu Pro Ile Ser Pro Leu Trp Ala Ile Leu 
    370                 375                 380                 


Phe Phe Ser Met Leu Leu Met Leu Gly Ile Asp Ser Gln Phe Cys Thr 
385                 390                 395                 400 


Val Glu Gly Phe Ile Thr Ala Leu Val Asp Glu Tyr Pro Arg Leu Leu 
                405                 410                 415     


Arg Asn Arg Arg Glu Leu Phe Ile Ala Ala Val Cys Ile Ile Ser Tyr 
            420                 425                 430         


Leu Ile Gly Leu Ser Asn Ile Thr Gln Gly Gly Ile Tyr Val Phe Lys 
        435                 440                 445             


Leu Phe Asp Tyr Tyr Ser Ala Ser Gly Met Ser Leu Leu Phe Leu Val 
    450                 455                 460                 


Phe Phe Glu Cys Val Ser Ile Ser Trp Phe Tyr Gly Val Asn Arg Phe 
465                 470                 475                 480 


Tyr Asp Asn Ile Gln Glu Met Val Gly Ser Arg Pro Cys Ile Trp Trp 
                485                 490                 495     


Lys Leu Cys Trp Ser Phe Phe Thr Pro Ile Ile Val Ala Gly Val Phe 
            500                 505                 510         


Ile Phe Ser Ala Val Gln Met Thr Pro Leu Thr Met Gly Asn Tyr Val 
        515                 520                 525             


Phe Pro Lys Trp Gly Gln Gly Val Gly Trp Leu Met Ala Leu Ser Ser 
    530                 535                 540                 


Met Val Leu Ile Pro Gly Tyr Met Ala Tyr Met Phe Leu Thr Leu Lys 
545                 550                 555                 560 


Gly Ser Leu Lys Gln Arg Ile Gln Val Met Val Gln Pro Ser Glu Asp 
                565                 570                 575     


Ile Val Arg Pro Glu Asn Gly Pro Glu Gln Pro Gln Ala Gly Ser Ser 
            580                 585                 590         


Thr Ser Lys Glu Ala Tyr Ile 
        595                 


<210>  4219
<211>  620
<212>  PRT
<213>  homo sapiens

<400>  4219

Met Ala Thr Lys Glu Lys Leu Gln Cys Leu Lys Asp Phe His Lys Asp 
1               5                   10                  15      


Ile Leu Lys Pro Ser Pro Gly Lys Ser Pro Gly Thr Arg Pro Glu Asp 
            20                  25                  30          


Glu Ala Glu Gly Lys Pro Pro Gln Arg Glu Lys Trp Ser Ser Lys Ile 
        35                  40                  45              


Asp Phe Val Leu Ser Val Ala Gly Gly Phe Val Gly Leu Gly Asn Val 
    50                  55                  60                  


Trp Arg Phe Pro Tyr Leu Cys Tyr Lys Asn Gly Gly Gly Ala Phe Leu 
65                  70                  75                  80  


Ile Pro Tyr Phe Ile Phe Leu Phe Gly Ser Gly Leu Pro Val Phe Phe 
                85                  90                  95      


Leu Glu Ile Ile Ile Gly Gln Tyr Thr Ser Glu Gly Gly Ile Thr Cys 
            100                 105                 110         


Trp Glu Lys Ile Cys Pro Leu Phe Ser Gly Ile Gly Tyr Ala Ser Val 
        115                 120                 125             


Val Ile Val Ser Leu Leu Asn Val Tyr Tyr Ile Val Ile Leu Ala Trp 
    130                 135                 140                 


Ala Thr Tyr Tyr Leu Phe Gln Ser Phe Gln Lys Glu Leu Pro Trp Ala 
145                 150                 155                 160 


His Cys Asn His Ser Trp Asn Thr Pro His Cys Met Glu Asp Thr Met 
                165                 170                 175     


Arg Lys Asn Lys Ser Val Trp Ile Thr Ile Ser Ser Thr Asn Phe Thr 
            180                 185                 190         


Ser Pro Val Ile Glu Phe Trp Glu Arg Asn Val Leu Ser Leu Ser Pro 
        195                 200                 205             


Gly Ile Asp His Pro Gly Ser Leu Lys Trp Asp Leu Ala Leu Cys Leu 
    210                 215                 220                 


Leu Leu Val Trp Leu Val Cys Phe Phe Cys Ile Trp Lys Gly Val Arg 
225                 230                 235                 240 


Ser Thr Gly Lys Val Val Tyr Phe Thr Ala Thr Phe Pro Phe Ala Met 
                245                 250                 255     


Leu Leu Val Leu Leu Val Arg Gly Leu Thr Leu Pro Gly Ala Gly Ala 
            260                 265                 270         


Gly Ile Lys Phe Tyr Leu Tyr Pro Asp Ile Thr Arg Leu Glu Asp Pro 
        275                 280                 285             


Gln Val Trp Ile Asp Ala Gly Thr Gln Ile Phe Phe Ser Tyr Ala Ile 
    290                 295                 300                 


Cys Leu Gly Ala Met Thr Ser Leu Gly Ser Tyr Asn Lys Tyr Lys Tyr 
305                 310                 315                 320 


Asn Ser Tyr Arg Asp Cys Met Leu Leu Gly Cys Leu Asn Ser Gly Thr 
                325                 330                 335     


Ser Phe Val Ser Gly Phe Ala Ile Phe Ser Ile Leu Gly Phe Met Ala 
            340                 345                 350         


Gln Glu Gln Gly Val Asp Ile Ala Asp Val Ala Glu Ser Gly Pro Gly 
        355                 360                 365             


Leu Ala Phe Ile Ala Tyr Pro Lys Ala Val Thr Met Met Pro Leu Pro 
    370                 375                 380                 


Thr Phe Trp Ser Ile Leu Phe Phe Ile Met Leu Leu Leu Leu Gly Leu 
385                 390                 395                 400 


Asp Ser Gln Phe Val Glu Val Glu Gly Gln Ile Thr Ser Leu Val Asp 
                405                 410                 415     


Leu Tyr Pro Ser Phe Leu Arg Lys Gly Tyr Arg Arg Glu Ile Phe Ile 
            420                 425                 430         


Ala Phe Val Cys Ser Ile Ser Tyr Leu Leu Gly Leu Thr Met Val Thr 
        435                 440                 445             


Glu Gly Gly Met Tyr Val Phe Gln Leu Phe Asp Tyr Tyr Ala Ala Ser 
    450                 455                 460                 


Gly Val Cys Leu Leu Trp Val Ala Phe Phe Glu Cys Phe Val Ile Ala 
465                 470                 475                 480 


Trp Ile Tyr Gly Gly Asp Asn Leu Tyr Asp Gly Ile Glu Asp Met Ile 
                485                 490                 495     


Gly Tyr Arg Pro Gly Pro Trp Met Lys Tyr Ser Trp Ala Val Ile Thr 
            500                 505                 510         


Pro Val Leu Cys Val Gly Cys Phe Ile Phe Ser Leu Val Lys Tyr Val 
        515                 520                 525             


Pro Leu Thr Tyr Asn Lys Thr Tyr Val Tyr Pro Asn Trp Ala Ile Gly 
    530                 535                 540                 


Leu Gly Trp Ser Leu Ala Leu Ser Ser Met Leu Cys Val Pro Leu Val 
545                 550                 555                 560 


Ile Val Ile Arg Leu Cys Gln Thr Glu Gly Pro Phe Leu Val Arg Val 
                565                 570                 575     


Lys Tyr Leu Leu Thr Pro Arg Glu Pro Asn Arg Trp Ala Val Glu Arg 
            580                 585                 590         


Glu Gly Ala Thr Pro Tyr Asn Ser Arg Thr Val Met Asn Gly Ala Leu 
        595                 600                 605             


Val Lys Pro Thr His Ile Ile Val Glu Thr Met Met 
    610                 615                 620 


<210>  4220
<211>  200
<212>  PRT
<213>  homo sapiens

<400>  4220

Met Ala Thr Lys Glu Lys Leu Gln Cys Leu Lys Asp Phe His Lys Asp 
1               5                   10                  15      


Ile Leu Lys Pro Ser Pro Gly Lys Ser Pro Gly Thr Arg Pro Glu Asp 
            20                  25                  30          


Glu Ala Glu Gly Lys Pro Pro Gln Arg Glu Lys Trp Ser Ser Lys Ile 
        35                  40                  45              


Asp Phe Val Leu Ser Val Ala Gly Gly Phe Val Gly Leu Gly Asn Val 
    50                  55                  60                  


Trp Arg Phe Pro Tyr Leu Cys Tyr Lys Asn Gly Gly Gly Ala Phe Leu 
65                  70                  75                  80  


Ile Pro Tyr Phe Ile Phe Leu Phe Gly Ser Gly Leu Pro Val Phe Phe 
                85                  90                  95      


Leu Glu Ile Ile Ile Gly Gln Tyr Thr Ser Glu Gly Gly Ile Thr Cys 
            100                 105                 110         


Trp Glu Lys Ile Cys Pro Leu Phe Ser Gly Ile Gly Tyr Ala Ser Val 
        115                 120                 125             


Val Ile Val Ser Leu Leu Asn Val Tyr Tyr Ile Val Ile Leu Ala Trp 
    130                 135                 140                 


Ala Thr Tyr Tyr Leu Phe Gln Ser Phe Gln Lys Glu Leu Pro Trp Ala 
145                 150                 155                 160 


His Cys Asn His Ser Trp Asn Thr Pro His Cys Met Glu Asp Thr Met 
                165                 170                 175     


Arg Lys Asn Lys Ser Val Trp Ile Thr Ile Ser Ser Thr Asn Phe Thr 
            180                 185                 190         


Ser Pro Val Ile Glu Phe Trp Glu 
        195                 200 


<210>  4221
<211>  109
<212>  PRT
<213>  homo sapiens

<400>  4221

Met Glu Asp Tyr Thr Lys Ile Glu Lys Ile Gly Glu Gly Thr Tyr Gly 
1               5                   10                  15      


Val Val Tyr Lys Gly Arg His Lys Thr Thr Gly Gln Val Val Ala Met 
            20                  25                  30          


Lys Lys Ile Arg Leu Glu Ser Glu Glu Glu Gly Val Pro Ser Thr Ala 
        35                  40                  45              


Ile Arg Glu Ile Ser Leu Leu Lys Glu Leu Arg His Pro Asn Ile Val 
    50                  55                  60                  


Ser Leu Gln Asp Val Leu Met Gln Asp Ser Arg Leu Tyr Leu Ile Phe 
65                  70                  75                  80  


Glu Phe Leu Ser Met Asp Leu Lys Lys Tyr Leu Asp Ser Ile Pro Pro 
                85                  90                  95      


Gly Gln Tyr Met Asp Ser Ser Leu Val Lys Val Lys Ala 
            100                 105                 


<210>  4222
<211>  559
<212>  PRT
<213>  homo sapiens

<400>  4222

Met Pro Leu Val Lys Arg Asn Ile Asp Pro Arg His Leu Cys His Thr 
1               5                   10                  15      


Ala Leu Pro Arg Gly Ile Lys Asn Glu Leu Glu Cys Val Thr Asn Ile 
            20                  25                  30          


Ser Leu Ala Asn Ile Ile Arg Gln Leu Ser Ser Leu Ser Lys Tyr Ala 
        35                  40                  45              


Glu Asp Ile Phe Gly Glu Leu Phe Asn Glu Ala His Ser Phe Ser Phe 
    50                  55                  60                  


Arg Val Asn Ser Leu Gln Glu Arg Val Asp Arg Leu Ser Val Ser Val 
65                  70                  75                  80  


Thr Gln Leu Asp Pro Lys Glu Glu Glu Leu Ser Leu Gln Asp Ile Thr 
                85                  90                  95      


Met Arg Lys Ala Phe Arg Ser Ser Thr Ile Gln Asp Gln Gln Leu Phe 
            100                 105                 110         


Asp Arg Lys Thr Leu Pro Ile Pro Leu Gln Glu Thr Tyr Asp Val Cys 
        115                 120                 125             


Glu Gln Pro Pro Pro Leu Asn Ile Leu Thr Pro Tyr Arg Asp Asp Gly 
    130                 135                 140                 


Lys Glu Gly Leu Lys Phe Tyr Thr Asn Pro Ser Tyr Phe Phe Asp Leu 
145                 150                 155                 160 


Trp Lys Glu Lys Met Leu Gln Asp Thr Glu Asp Lys Arg Lys Glu Lys 
                165                 170                 175     


Arg Lys Gln Lys Gln Lys Asn Leu Asp Arg Pro His Glu Pro Glu Lys 
            180                 185                 190         


Val Pro Arg Ala Pro His Asp Arg Arg Arg Glu Trp Gln Lys Leu Ala 
        195                 200                 205             


Gln Gly Pro Glu Leu Ala Glu Asp Asp Ala Asn Leu Leu His Lys His 
    210                 215                 220                 


Ile Glu Val Ala Asn Gly Pro Ala Ser His Phe Glu Thr Arg Pro Gln 
225                 230                 235                 240 


Thr Tyr Val Asp His Met Asp Gly Ser Tyr Ser Leu Ser Ala Leu Pro 
                245                 250                 255     


Phe Ser Gln Met Ser Glu Leu Leu Thr Arg Ala Glu Glu Arg Val Leu 
            260                 265                 270         


Val Arg Pro His Glu Pro Pro Pro Pro Pro Pro Met His Gly Ala Gly 
        275                 280                 285             


Asp Ala Lys Pro Ile Pro Thr Cys Ile Ser Ser Ala Thr Gly Leu Ile 
    290                 295                 300                 


Glu Asn Arg Pro Gln Ser Pro Ala Thr Gly Arg Thr Pro Val Phe Val 
305                 310                 315                 320 


Ser Pro Thr Pro Pro Pro Pro Pro Pro Pro Leu Pro Ser Ala Leu Ser 
                325                 330                 335     


Thr Ser Ser Leu Arg Ala Ser Met Thr Ser Thr Pro Pro Pro Pro Val 
            340                 345                 350         


Pro Pro Pro Pro Pro Pro Pro Ala Thr Ala Leu Gln Ala Pro Ala Val 
        355                 360                 365             


Pro Pro Pro Pro Ala Pro Leu Gln Ile Ala Pro Gly Val Leu His Pro 
    370                 375                 380                 


Ala Pro Pro Pro Ile Ala Pro Pro Leu Val Gln Pro Ser Pro Pro Val 
385                 390                 395                 400 


Ala Arg Ala Ala Pro Val Cys Glu Thr Val Pro Val His Pro Leu Pro 
                405                 410                 415     


Gln Gly Glu Val Gln Gly Leu Pro Pro Pro Pro Pro Pro Pro Pro Leu 
            420                 425                 430         


Pro Pro Pro Gly Ile Arg Pro Ser Ser Pro Val Thr Val Thr Ala Leu 
        435                 440                 445             


Ala His Pro Pro Ser Gly Leu His Pro Thr Pro Ser Thr Ala Pro Gly 
    450                 455                 460                 


Pro His Val Pro Leu Met Pro Pro Ser Pro Pro Ser Gln Val Ile Pro 
465                 470                 475                 480 


Ala Ser Glu Pro Lys Arg His Pro Ser Thr Leu Pro Val Ile Ser Asp 
                485                 490                 495     


Ala Arg Ser Val Leu Leu Glu Ala Ile Arg Lys Gly Ile Gln Leu Arg 
            500                 505                 510         


Lys Val Glu Glu Gln Arg Glu Gln Glu Ala Lys His Glu Arg Ile Glu 
        515                 520                 525             


Asn Asp Val Ala Thr Ile Leu Ser Arg Arg Ile Ala Val Glu Tyr Ser 
    530                 535                 540                 


Asp Ser Glu Asp Asp Ser Glu Phe Asp Glu Val Asp Trp Leu Glu 
545                 550                 555                 


<210>  4223
<211>  847
<212>  PRT
<213>  homo sapiens

<400>  4223

Met Ser Leu Phe Lys Ala Arg Asp Trp Trp Ser Thr Ile Leu Gly Asp 
1               5                   10                  15      


Lys Glu Glu Phe Asp Gln Gly Cys Leu Cys Leu Ala Asn Val Asp Asn 
            20                  25                  30          


Ser Gly Asn Gly Gln Asp Lys Ile Ile Val Gly Ser Phe Met Gly Tyr 
        35                  40                  45              


Leu Arg Ile Phe Ser Pro His Pro Ala Lys Thr Gly Asp Gly Ala Gln 
    50                  55                  60                  


Ala Glu Asp Leu Leu Leu Glu Val Asp Leu Arg Asp Pro Val Leu Gln 
65                  70                  75                  80  


Val Glu Val Gly Lys Phe Val Ser Gly Thr Glu Met Leu His Leu Ala 
                85                  90                  95      


Val Leu His Ser Arg Lys Leu Cys Val Tyr Ser Val Ser Gly Thr Leu 
            100                 105                 110         


Gly Asn Val Glu His Gly Asn Gln Cys Gln Met Lys Leu Met Tyr Glu 
        115                 120                 125             


His Asn Leu Gln Arg Thr Ala Cys Asn Met Thr Tyr Gly Ser Phe Gly 
    130                 135                 140                 


Gly Val Lys Gly Arg Asp Leu Ile Cys Ile Gln Ser Met Asp Gly Met 
145                 150                 155                 160 


Leu Met Val Phe Glu Gln Glu Ser Tyr Ala Phe Gly Arg Phe Leu Pro 
                165                 170                 175     


Gly Phe Leu Leu Pro Gly Pro Leu Ala Tyr Ser Ser Arg Thr Asp Ser 
            180                 185                 190         


Phe Leu Thr Val Ser Ser Cys Gln Gln Val Glu Ser Tyr Lys Tyr Gln 
        195                 200                 205             


Val Leu Ala Phe Ala Thr Asp Ala Asp Lys Arg Gln Glu Thr Glu Gln 
    210                 215                 220                 


Gln Lys Leu Gly Ser Gly Lys Arg Leu Val Val Asp Trp Thr Leu Asn 
225                 230                 235                 240 


Ile Gly Glu Gln Ala Leu Asp Ile Cys Ile Val Ser Phe Asn Gln Ser 
                245                 250                 255     


Ala Ser Ser Val Phe Val Leu Gly Glu Arg Asn Phe Phe Cys Leu Lys 
            260                 265                 270         


Asp Asn Gly Gln Ile Arg Phe Met Lys Lys Leu Asp Trp Ser Pro Ser 
        275                 280                 285             


Cys Phe Leu Pro Tyr Cys Ser Val Ser Glu Gly Thr Ile Asn Thr Leu 
    290                 295                 300                 


Ile Gly Asn His Asn Asn Met Leu His Ile Tyr Gln Asp Val Thr Leu 
305                 310                 315                 320 


Lys Trp Ala Thr Gln Leu Pro His Ile Pro Val Ala Val Arg Val Gly 
                325                 330                 335     


Cys Leu His Asp Leu Lys Gly Val Ile Val Thr Leu Ser Asp Asp Gly 
            340                 345                 350         


His Leu Gln Cys Ser Tyr Leu Gly Thr Asp Pro Ser Leu Phe Gln Ala 
        355                 360                 365             


Pro Asn Val Gln Ser Arg Glu Leu Asn Tyr Asp Glu Leu Asp Val Glu 
    370                 375                 380                 


Met Lys Glu Leu Gln Lys Ile Ile Lys Asp Val Asn Lys Ser Gln Gly 
385                 390                 395                 400 


Val Trp Pro Met Thr Glu Arg Glu Asp Asp Leu Asn Val Ser Val Val 
                405                 410                 415     


Val Ser Pro Asn Phe Asp Ser Val Ser Gln Ala Thr Asp Val Glu Val 
            420                 425                 430         


Gly Thr Asp Leu Val Pro Ser Val Thr Val Lys Val Thr Leu Gln Asn 
        435                 440                 445             


Arg Val Ile Leu Gln Lys Ala Lys Leu Ser Val Tyr Val Gln Pro Pro 
    450                 455                 460                 


Leu Glu Leu Thr Cys Asp Gln Phe Thr Phe Glu Phe Met Ser Ile Pro 
465                 470                 475                 480 


Arg Val Ile Gln Cys Lys Phe Arg Leu Pro Leu Lys Leu Ile Cys Leu 
                485                 490                 495     


Pro Gly Gln Pro Ser Lys Thr Ala Ser His Lys Ile Thr Ile Asp Thr 
            500                 505                 510         


Asn Lys Ser Pro Val Ser Leu Leu Ser Leu Phe Pro Gly Phe Ala Ser 
        515                 520                 525             


Gln Ser Asp Asp Asp Gln Val Asn Val Met Gly Phe His Phe Leu Gly 
    530                 535                 540                 


Gly Ala Arg Ile Thr Val Leu Ala Ser Lys Thr Ser Gln Arg Tyr Arg 
545                 550                 555                 560 


Ile Gln Ser Glu Gln Phe Glu Asp Leu Trp Leu Ile Thr Asn Glu Leu 
                565                 570                 575     


Ile Leu Arg Leu Gln Glu Tyr Phe Glu Lys Gln Gly Val Lys Asp Phe 
            580                 585                 590         


Ala Cys Ser Phe Ser Gly Ser Ile Pro Leu Gln Glu Tyr Phe Glu Leu 
        595                 600                 605             


Ile Asp His His Phe Glu Leu Arg Ile Asn Gly Glu Lys Leu Glu Glu 
    610                 615                 620                 


Leu Leu Ser Glu Arg Ala Val Gln Phe Arg Ala Ile Gln Arg Arg Leu 
625                 630                 635                 640 


Leu Ala Arg Phe Lys Asp Lys Thr Pro Ala Pro Leu Gln His Leu Asp 
                645                 650                 655     


Thr Leu Leu Asp Gly Thr Tyr Lys Gln Val Ile Ala Leu Ala Asp Ala 
            660                 665                 670         


Val Glu Glu Asn Gln Gly Asn Leu Phe Gln Ser Phe Thr Arg Leu Lys 
        675                 680                 685             


Ser Ala Thr His Leu Val Ile Leu Leu Ile Ala Leu Trp Gln Lys Leu 
    690                 695                 700                 


Ser Ala Asp Gln Val Ala Ile Leu Glu Ala Ala Phe Leu Pro Leu Gln 
705                 710                 715                 720 


Glu Asp Thr Gln Glu Leu Gly Trp Glu Glu Thr Val Asp Ala Ala Ile 
                725                 730                 735     


Ser His Leu Leu Lys Thr Cys Leu Ser Lys Ser Ser Lys Glu Gln Ala 
            740                 745                 750         


Leu Asn Leu Asn Ser Gln Leu Asn Ile Pro Lys Asp Thr Ser Gln Leu 
        755                 760                 765             


Lys Lys His Ile Thr Leu Leu Cys Asp Arg Leu Ser Lys Gly Gly Arg 
    770                 775                 780                 


Leu Cys Leu Ser Thr Asp Ala Ala Ala Pro Gln Thr Met Val Met Pro 
785                 790                 795                 800 


Gly Gly Cys Thr Thr Ile Pro Glu Ser Asp Leu Glu Glu Arg Ser Val 
                805                 810                 815     


Glu Gln Asp Ser Thr Glu Leu Phe Thr Asn His Arg His Leu Thr Ala 
            820                 825                 830         


Glu Thr Pro Arg Pro Glu Val Ser Pro Leu Gln Gly Val Ser Glu 
        835                 840                 845         


<210>  4224
<211>  238
<212>  PRT
<213>  homo sapiens

<400>  4224

Met Arg Phe Lys Asn Arg Phe Gln Arg Phe Met Asn His Arg Ala Pro 
1               5                   10                  15      


Ala Asn Gly Arg Tyr Lys Pro Thr Cys Tyr Glu His Ala Ala Asn Cys 
            20                  25                  30          


Tyr Thr His Ala Phe Leu Ile Val Pro Ala Ile Val Gly Ser Ala Leu 
        35                  40                  45              


Leu His Arg Leu Ser Asp Asp Cys Trp Glu Lys Ile Thr Ala Trp Ile 
    50                  55                  60                  


Tyr Gly Met Gly Leu Cys Ala Leu Phe Ile Val Ser Thr Val Phe His 
65                  70                  75                  80  


Ile Val Ser Trp Lys Lys Ser His Leu Arg Thr Val Glu His Cys Phe 
                85                  90                  95      


His Met Cys Asp Arg Met Val Ile Tyr Phe Phe Ile Ala Ala Ser Tyr 
            100                 105                 110         


Ala Pro Trp Leu Asn Leu Arg Glu Leu Gly Pro Leu Ala Ser His Met 
        115                 120                 125             


Arg Trp Phe Ile Trp Leu Met Ala Ala Gly Gly Thr Ile Tyr Val Phe 
    130                 135                 140                 


Leu Tyr His Glu Lys Tyr Lys Val Val Glu Leu Phe Phe Tyr Leu Thr 
145                 150                 155                 160 


Met Gly Phe Ser Pro Ala Leu Val Val Thr Ser Met Asn Asn Thr Asp 
                165                 170                 175     


Gly Leu Gln Glu Leu Ala Cys Gly Gly Leu Ile Tyr Cys Leu Gly Val 
            180                 185                 190         


Val Phe Phe Lys Ser Asp Gly Ile Ile Pro Phe Ala His Ala Ile Trp 
        195                 200                 205             


His Leu Phe Val Ala Thr Ala Ala Ala Val His Tyr Tyr Ala Ile Trp 
    210                 215                 220                 


Lys Tyr Leu Tyr Arg Ser Pro Thr Asp Phe Met Arg His Leu 
225                 230                 235             


<210>  4225
<211>  582
<212>  PRT
<213>  homo sapiens

<400>  4225

Met Ser Pro Ala Pro Arg Pro Pro Arg Cys Leu Leu Leu Pro Leu Leu 
1               5                   10                  15      


Thr Leu Gly Thr Ala Leu Ala Ser Leu Gly Ser Ala Gln Ser Ser Ser 
            20                  25                  30          


Phe Ser Pro Glu Ala Trp Leu Gln Gln Tyr Gly Tyr Leu Pro Pro Gly 
        35                  40                  45              


Asp Leu Arg Thr His Thr Gln Arg Ser Pro Gln Ser Leu Ser Ala Ala 
    50                  55                  60                  


Ile Ala Ala Met Gln Lys Phe Tyr Gly Leu Gln Val Thr Gly Lys Ala 
65                  70                  75                  80  


Asp Ala Asp Thr Met Lys Ala Met Arg Arg Pro Arg Cys Gly Val Pro 
                85                  90                  95      


Asp Lys Phe Gly Ala Glu Ile Lys Ala Asn Val Arg Arg Lys Arg Tyr 
            100                 105                 110         


Ala Ile Gln Gly Leu Lys Trp Gln His Asn Glu Ile Thr Phe Cys Ile 
        115                 120                 125             


Gln Asn Tyr Thr Pro Lys Val Gly Glu Tyr Ala Thr Tyr Glu Ala Ile 
    130                 135                 140                 


Arg Lys Ala Phe Arg Val Trp Glu Ser Ala Thr Pro Leu Arg Phe Arg 
145                 150                 155                 160 


Glu Val Pro Tyr Ala Tyr Ile Arg Glu Gly His Glu Lys Gln Ala Asp 
                165                 170                 175     


Ile Met Ile Phe Phe Ala Glu Gly Phe His Gly Asp Ser Thr Pro Phe 
            180                 185                 190         


Asp Gly Glu Gly Gly Phe Leu Ala His Ala Tyr Phe Pro Gly Pro Asn 
        195                 200                 205             


Ile Gly Gly Asp Thr His Phe Asp Ser Ala Glu Pro Trp Thr Val Arg 
    210                 215                 220                 


Asn Glu Asp Leu Asn Gly Asn Asp Ile Phe Leu Val Ala Val His Glu 
225                 230                 235                 240 


Leu Gly His Ala Leu Gly Leu Glu His Ser Ser Asp Pro Ser Ala Ile 
                245                 250                 255     


Met Ala Pro Phe Tyr Gln Trp Met Asp Thr Glu Asn Phe Val Leu Pro 
            260                 265                 270         


Asp Asp Asp Arg Arg Gly Ile Gln Gln Leu Tyr Gly Gly Glu Ser Gly 
        275                 280                 285             


Phe Pro Thr Lys Met Pro Pro Gln Pro Arg Thr Thr Ser Arg Pro Ser 
    290                 295                 300                 


Val Pro Asp Lys Pro Lys Asn Pro Thr Tyr Gly Pro Asn Ile Cys Asp 
305                 310                 315                 320 


Gly Asn Phe Asp Thr Val Ala Met Leu Arg Gly Glu Met Phe Val Phe 
                325                 330                 335     


Lys Glu Arg Trp Phe Trp Arg Val Arg Asn Asn Gln Val Met Asp Gly 
            340                 345                 350         


Tyr Pro Met Pro Ile Gly Gln Phe Trp Arg Gly Leu Pro Ala Ser Ile 
        355                 360                 365             


Asn Thr Ala Tyr Glu Arg Lys Asp Gly Lys Phe Val Phe Phe Lys Gly 
    370                 375                 380                 


Asp Lys His Trp Val Phe Asp Glu Ala Ser Leu Glu Pro Gly Tyr Pro 
385                 390                 395                 400 


Lys His Ile Lys Glu Leu Gly Arg Gly Leu Pro Thr Asp Lys Ile Asp 
                405                 410                 415     


Ala Ala Leu Phe Trp Met Pro Asn Gly Lys Thr Tyr Phe Phe Arg Gly 
            420                 425                 430         


Asn Lys Tyr Tyr Arg Phe Asn Glu Glu Leu Arg Ala Val Asp Ser Glu 
        435                 440                 445             


Tyr Pro Lys Asn Ile Lys Val Trp Glu Gly Ile Pro Glu Ser Pro Arg 
    450                 455                 460                 


Gly Ser Phe Met Gly Ser Asp Glu Val Phe Thr Tyr Phe Tyr Lys Gly 
465                 470                 475                 480 


Asn Lys Tyr Trp Lys Phe Asn Asn Gln Lys Leu Lys Val Glu Pro Gly 
                485                 490                 495     


Tyr Pro Lys Ser Ala Leu Arg Asp Trp Met Gly Cys Pro Ser Gly Gly 
            500                 505                 510         


Arg Pro Asp Glu Gly Thr Glu Glu Glu Thr Glu Val Ile Ile Ile Glu 
        515                 520                 525             


Val Asp Glu Glu Gly Gly Gly Ala Val Ser Ala Ala Ala Val Val Leu 
    530                 535                 540                 


Pro Val Leu Leu Leu Leu Leu Val Leu Ala Val Gly Leu Ala Val Phe 
545                 550                 555                 560 


Phe Phe Arg Arg His Gly Thr Pro Arg Arg Leu Leu Tyr Cys Gln Arg 
                565                 570                 575     


Ser Leu Leu Asp Lys Val 
            580         


<210>  4226
<211>  582
<212>  PRT
<213>  homo sapiens

<400>  4226

Met Ser Ile Glu Thr Leu Leu Glu Ala Ala Arg Phe Leu Glu Trp Gln 
1               5                   10                  15      


Ala Gln Gln Gln Gln Arg Ala Arg Glu Glu Gln Glu Arg Leu Arg Leu 
            20                  25                  30          


Glu Gln Glu Arg Glu Gln Glu Gln Lys Lys Ala Asn Ser Leu Ala Arg 
        35                  40                  45              


Leu Ala His Thr Leu Pro Val Glu Glu Pro Arg Met Glu Ala Pro Pro 
    50                  55                  60                  


Leu Pro Leu Ser Pro Pro Ala Pro Pro Pro Ala Pro Pro Pro Pro Leu 
65                  70                  75                  80  


Ala Thr Pro Ala Pro Leu Thr Val Ile Pro Ile Pro Val Val Thr Asn 
                85                  90                  95      


Ser Pro Gln Pro Leu Pro Pro Pro Pro Pro Leu Pro Ala Ala Ala Gln 
            100                 105                 110         


Pro Leu Pro Leu Ala Pro Arg Gln Pro Ala Leu Val Gly Ala Pro Gly 
        115                 120                 125             


Leu Ser Ile Lys Glu Pro Ala Pro Leu Pro Ser Arg Pro Gln Val Pro 
    130                 135                 140                 


Thr Pro Ala Pro Leu Leu Pro Asp Ser Lys Ala Thr Ile Pro Pro Asn 
145                 150                 155                 160 


Gly Ser Pro Lys Pro Leu Gln Pro Leu Pro Thr Pro Val Leu Thr Ile 
                165                 170                 175     


Ala Pro His Pro Gly Val Gln Pro Gln Leu Ala Pro Gln Gln Pro Pro 
            180                 185                 190         


Pro Pro Thr Leu Gly Thr Leu Lys Leu Ala Pro Ala Glu Glu Val Lys 
        195                 200                 205             


Ser Ser Glu Gln Lys Lys Arg Pro Gly Gly Ile Gly Thr Arg Glu Val 
    210                 215                 220                 


His Asn Lys Leu Glu Lys Asn Arg Arg Ala His Leu Lys Glu Cys Phe 
225                 230                 235                 240 


Glu Thr Leu Lys Arg Asn Ile Pro Asn Val Asp Asp Lys Lys Thr Ser 
                245                 250                 255     


Asn Leu Ser Val Leu Arg Thr Ala Leu Arg Tyr Ile Gln Ser Leu Lys 
            260                 265                 270         


Arg Lys Glu Lys Glu Tyr Glu His Glu Met Glu Arg Leu Ala Arg Glu 
        275                 280                 285             


Lys Ile Ala Thr Gln Gln Arg Leu Ala Glu Leu Lys His Glu Leu Ser 
    290                 295                 300                 


Gln Trp Met Asp Val Leu Glu Ile Asp Arg Val Leu Arg Gln Thr Gly 
305                 310                 315                 320 


Gln Pro Glu Asp Asp Gln Ala Ser Thr Ser Thr Ala Ser Glu Gly Glu 
                325                 330                 335     


Asp Asn Ile Asp Glu Asp Met Glu Glu Asp Arg Ala Gly Leu Gly Pro 
            340                 345                 350         


Pro Lys Leu Ser His Arg Pro Gln Pro Glu Leu Leu Lys Ser Thr Leu 
        355                 360                 365             


Pro Pro Pro Ser Thr Thr Pro Ala Pro Leu Pro Pro His Pro His Pro 
    370                 375                 380                 


His Pro His Ser Val Ala Leu Pro Pro Ala His Leu Pro Val Gln Gln 
385                 390                 395                 400 


Gln Gln Pro Gln Gln Lys Thr Pro Leu Pro Ala Pro Pro Pro Pro Pro 
                405                 410                 415     


Ala Ala Pro Ala Gln Thr Leu Val Pro Ala Pro Ala His Leu Val Ala 
            420                 425                 430         


Thr Ala Gly Gly Gly Ser Thr Val Ile Ala His Thr Ala Thr Thr His 
        435                 440                 445             


Ala Ser Val Ile Gln Thr Val Asn His Val Leu Gln Gly Pro Gly Gly 
    450                 455                 460                 


Lys His Ile Ala His Ile Ala Pro Ser Ala Pro Ser Pro Ala Val Gln 
465                 470                 475                 480 


Leu Ala Pro Ala Thr Pro Pro Ile Gly His Ile Thr Val His Pro Ala 
                485                 490                 495     


Thr Leu Asn His Val Ala His Leu Gly Ser Gln Leu Pro Leu Tyr Pro 
            500                 505                 510         


Gln Pro Val Ala Val Ser His Ile Ala His Thr Leu Ser His Gln Gln 
        515                 520                 525             


Val Asn Gly Thr Ala Gly Leu Gly Pro Pro Ala Thr Val Met Ala Lys 
    530                 535                 540                 


Pro Ala Val Gly Ala Gln Val Val His His Pro Gln Leu Val Gly Gln 
545                 550                 555                 560 


Thr Val Leu Asn Pro Val Thr Met Val Thr Met Pro Ser Phe Pro Val 
                565                 570                 575     


Ser Thr Leu Lys Leu Ala 
            580         


<210>  4227
<211>  371
<212>  PRT
<213>  homo sapiens

<400>  4227

Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Pro Gly Gln Thr Pro Glu Ala Ala Lys Glu Ala Glu Leu Ala Ala Arg 
            20                  25                  30          


Ile Leu Leu Asp Gln Gly Gln Thr His Ser Val Glu Thr Pro Tyr Gly 
        35                  40                  45              


Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg Pro Ala 
    50                  55                  60                  


Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys Phe Gln 
65                  70                  75                  80  


Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn Phe Val 
                85                  90                  95      


Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro Val Phe 
            100                 105                 110         


Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp Met Ile 
        115                 120                 125             


Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly Val Gly 
    130                 135                 140                 


Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn His Pro 
145                 150                 155                 160 


Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn Ala Lys 
                165                 170                 175     


Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr Ser Ser 
            180                 185                 190         


Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu Leu Ser 
        195                 200                 205             


Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr His Ala 
    210                 215                 220                 


Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn Asn Arg 
225                 230                 235                 240 


Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg Cys Pro 
                245                 250                 255     


Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala Val Val 
            260                 265                 270         


Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu Lys Met 
        275                 280                 285             


Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Gln Pro Gly Lys Leu Thr 
    290                 295                 300                 


Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr Met Ala Ser Ser 
305                 310                 315                 320 


Cys Met Thr Arg Leu Ser Arg Ser Arg Thr Ala Ser Leu Thr Ser Ala 
                325                 330                 335     


Ala Ser Val Asp Gly Asn Arg Ser Arg Ser Arg Thr Leu Ser Gln Ser 
            340                 345                 350         


Ser Glu Ser Gly Thr Leu Ser Ser Gly Pro Pro Gly His Thr Met Glu 
        355                 360                 365             


Val Ser Cys 
    370     


<210>  4228
<211>  357
<212>  PRT
<213>  homo sapiens

<400>  4228

Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Pro Gly Gln Thr Pro Glu Ala Ala Lys Thr His Ser Val Glu Thr Pro 
            20                  25                  30          


Tyr Gly Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg 
        35                  40                  45              


Pro Ala Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys 
    50                  55                  60                  


Phe Gln Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn 
65                  70                  75                  80  


Phe Val Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro 
                85                  90                  95      


Val Phe Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp 
            100                 105                 110         


Met Ile Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly 
        115                 120                 125             


Val Gly Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn 
    130                 135                 140                 


His Pro Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn 
145                 150                 155                 160 


Ala Lys Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr 
                165                 170                 175     


Ser Ser Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu 
            180                 185                 190         


Leu Ser Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr 
        195                 200                 205             


His Ala Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn 
    210                 215                 220                 


Asn Arg Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg 
225                 230                 235                 240 


Cys Pro Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala 
                245                 250                 255     


Val Val Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu 
            260                 265                 270         


Lys Met Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Gln Pro Gly Lys 
        275                 280                 285             


Leu Thr Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr Met Ala 
    290                 295                 300                 


Ser Ser Cys Met Thr Arg Leu Ser Arg Ser Arg Thr Ala Ser Leu Thr 
305                 310                 315                 320 


Ser Ala Ala Ser Val Asp Gly Asn Arg Ser Arg Ser Arg Thr Leu Ser 
                325                 330                 335     


Gln Ser Ser Glu Ser Gly Thr Leu Ser Ser Gly Pro Pro Gly His Thr 
            340                 345                 350         


Met Glu Val Ser Cys 
        355         


<210>  4229
<211>  399
<212>  PRT
<213>  homo sapiens

<400>  4229

Met Glu Asp Gly Val Tyr Glu Pro Pro Asp Leu Thr Pro Glu Glu Arg 
1               5                   10                  15      


Met Glu Leu Glu Asn Ile Arg Arg Arg Lys Gln Glu Leu Leu Val Glu 
            20                  25                  30          


Ile Gln Arg Leu Arg Glu Glu Leu Ser Glu Ala Met Ser Glu Val Glu 
        35                  40                  45              


Gly Leu Glu Ala Asn Glu Gly Ser Lys Thr Leu Gln Arg Asn Arg Lys 
    50                  55                  60                  


Met Ala Met Gly Arg Lys Lys Phe Asn Met Asp Pro Lys Lys Gly Ile 
65                  70                  75                  80  


Gln Phe Leu Val Glu Asn Glu Leu Leu Gln Asn Thr Pro Glu Glu Ile 
                85                  90                  95      


Ala Arg Phe Leu Tyr Lys Gly Glu Gly Leu Asn Lys Thr Ala Ile Gly 
            100                 105                 110         


Asp Tyr Leu Gly Glu Arg Glu Glu Leu Asn Leu Ala Val Leu His Ala 
        115                 120                 125             


Phe Val Asp Leu His Glu Phe Thr Asp Leu Asn Leu Val Gln Ala Leu 
    130                 135                 140                 


Arg Gln Phe Leu Trp Ser Phe Arg Leu Pro Gly Glu Ala Gln Lys Ile 
145                 150                 155                 160 


Asp Arg Met Met Glu Ala Phe Ala Gln Arg Tyr Cys Leu Cys Asn Pro 
                165                 170                 175     


Gly Val Phe Gln Ser Thr Asp Thr Cys Tyr Val Leu Ser Phe Ala Val 
            180                 185                 190         


Ile Met Leu Asn Thr Ser Leu His Asn Pro Asn Val Arg Asp Lys Pro 
        195                 200                 205             


Gly Leu Glu Arg Phe Val Ala Met Asn Arg Gly Ile Asn Glu Gly Gly 
    210                 215                 220                 


Asp Leu Pro Glu Glu Leu Leu Arg Asn Leu Tyr Asp Ser Ile Arg Asn 
225                 230                 235                 240 


Glu Pro Phe Lys Ile Pro Glu Asp Asp Gly Asn Asp Leu Thr His Thr 
                245                 250                 255     


Phe Phe Asn Pro Asp Arg Glu Gly Trp Leu Leu Lys Leu Gly Gly Arg 
            260                 265                 270         


Val Lys Thr Trp Lys Arg Arg Trp Phe Ile Leu Thr Asp Asn Cys Leu 
        275                 280                 285             


Tyr Tyr Phe Glu Tyr Thr Thr Asp Lys Glu Pro Arg Gly Ile Ile Pro 
    290                 295                 300                 


Leu Glu Asn Leu Ser Ile Arg Glu Val Asp Asp Pro Arg Lys Pro Asn 
305                 310                 315                 320 


Cys Phe Glu Leu Tyr Ile Pro Asn Asn Lys Gly Gln Leu Ile Lys Ala 
                325                 330                 335     


Cys Lys Thr Glu Ala Asp Gly Arg Val Val Glu Gly Asn His Met Val 
            340                 345                 350         


Tyr Arg Ile Ser Ala Pro Thr Gln Glu Glu Lys Asp Glu Trp Ile Lys 
        355                 360                 365             


Ser Ile Gln Ala Ala Val Ser Val Asp Pro Phe Tyr Glu Met Leu Ala 
    370                 375                 380                 


Ala Arg Lys Lys Arg Ile Ser Val Lys Lys Lys Gln Glu Gln Pro 
385                 390                 395                 


<210>  4230
<211>  413
<212>  PRT
<213>  homo sapiens

<400>  4230

Met Ala Glu Ala Gly Pro Gln Ala Pro Pro Pro Pro Gly Thr Pro Ser 
1               5                   10                  15      


Arg His Glu Lys Ser Leu Gly Leu Leu Thr Thr Lys Phe Val Ser Leu 
            20                  25                  30          


Leu Gln Glu Ala Lys Asp Gly Val Leu Asp Leu Lys Leu Ala Ala Asp 
        35                  40                  45              


Thr Leu Ala Val Arg Gln Lys Arg Arg Ile Tyr Asp Ile Thr Asn Val 
    50                  55                  60                  


Leu Glu Gly Ile Gly Leu Ile Glu Lys Lys Ser Lys Asn Ser Ile Gln 
65                  70                  75                  80  


Trp Lys Gly Val Gly Pro Gly Cys Asn Thr Arg Glu Ile Ala Asp Lys 
                85                  90                  95      


Leu Ile Glu Leu Lys Ala Glu Ile Glu Glu Leu Gln Gln Arg Glu Gln 
            100                 105                 110         


Glu Leu Asp Gln His Lys Val Trp Val Gln Gln Ser Ile Arg Asn Val 
        115                 120                 125             


Thr Glu Asp Val Gln Asn Ser Cys Leu Ala Tyr Val Thr His Glu Asp 
    130                 135                 140                 


Ile Cys Arg Cys Phe Ala Gly Asp Thr Leu Leu Ala Ile Arg Ala Pro 
145                 150                 155                 160 


Ser Gly Thr Ser Leu Glu Val Pro Ile Pro Glu Gly Leu Asn Gly Gln 
                165                 170                 175     


Lys Lys Tyr Gln Ile His Leu Lys Ser Val Ser Gly Pro Ile Glu Val 
            180                 185                 190         


Leu Leu Val Asn Lys Glu Ala Trp Ser Ser Pro Pro Val Ala Val Pro 
        195                 200                 205             


Val Pro Pro Pro Glu Asp Leu Leu Gln Ser Pro Ser Ala Val Ser Thr 
    210                 215                 220                 


Pro Pro Pro Leu Pro Lys Pro Ala Leu Ala Gln Ser Gln Glu Ala Ser 
225                 230                 235                 240 


Arg Pro Asn Ser Pro Gln Leu Thr Pro Thr Ala Val Pro Gly Ser Ala 
                245                 250                 255     


Glu Val Gln Gly Met Ala Gly Pro Ala Ala Glu Ile Thr Val Ser Gly 
            260                 265                 270         


Gly Pro Gly Thr Asp Ser Lys Asp Ser Gly Glu Leu Ser Ser Leu Pro 
        275                 280                 285             


Leu Gly Pro Thr Thr Leu Asp Thr Arg Pro Leu Gln Ser Ser Ala Leu 
    290                 295                 300                 


Leu Asp Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Asn 
305                 310                 315                 320 


Ser Asn Ser Ser Ser Ser Ser Gly Pro Asn Pro Ser Thr Ser Phe Glu 
                325                 330                 335     


Pro Ile Lys Ala Asp Pro Thr Gly Val Leu Glu Leu Pro Lys Glu Leu 
            340                 345                 350         


Ser Glu Ile Phe Asp Pro Thr Arg Glu Cys Met Ser Ser Glu Leu Leu 
        355                 360                 365             


Glu Glu Leu Met Ser Ser Glu Val Phe Ala Pro Leu Leu Arg Leu Ser 
    370                 375                 380                 


Pro Pro Pro Gly Asp His Asp Tyr Ile Tyr Asn Leu Asp Glu Ser Glu 
385                 390                 395                 400 


Gly Val Cys Asp Leu Phe Asp Val Pro Val Leu Asn Leu 
                405                 410             


<210>  4231
<211>  193
<212>  PRT
<213>  homo sapiens

<400>  4231

Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Leu Gln Asp Leu 
1               5                   10                  15      


Arg Glu Asn Thr Glu Phe Thr Asp His Glu Leu Gln Glu Trp Tyr Lys 
            20                  25                  30          


Gly Phe Leu Lys Asp Cys Pro Thr Gly His Leu Thr Val Asp Glu Phe 
        35                  40                  45              


Lys Lys Ile Tyr Ala Asn Phe Phe Pro Tyr Gly Asp Ala Ser Lys Phe 
    50                  55                  60                  


Ala Glu His Val Phe Arg Thr Phe Asp Thr Asn Gly Asp Gly Thr Ile 
65                  70                  75                  80  


Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser Val Thr Ser Arg Gly Lys 
                85                  90                  95      


Leu Glu Gln Lys Leu Lys Trp Ala Phe Ser Met Tyr Asp Leu Asp Gly 
            100                 105                 110         


Asn Gly Tyr Ile Ser Arg Ser Glu Met Leu Glu Ile Val Gln Ala Ile 
        115                 120                 125             


Tyr Lys Met Val Ser Ser Val Met Lys Met Pro Glu Asp Glu Ser Thr 
    130                 135                 140                 


Pro Glu Lys Arg Thr Asp Lys Ile Phe Arg Gln Met Asp Thr Asn Asn 
145                 150                 155                 160 


Asp Gly Lys Leu Ser Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp 
                165                 170                 175     


Pro Ser Ile Val Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Ser Gln 
            180                 185                 190         


Phe 
    


<210>  4232
<211>  503
<212>  PRT
<213>  homo sapiens

<400>  4232

Met Glu Glu His Gly Val Thr Gln Thr Glu His Met Ala Thr Ile Glu 
1               5                   10                  15      


Ala His Ala Val Ala Gln Gln Val Gln Gln Val His Val Ala Thr Tyr 
            20                  25                  30          


Thr Glu His Ser Met Leu Ser Ala Asp Glu Asp Ser Pro Ser Ser Pro 
        35                  40                  45              


Glu Asp Thr Ser Tyr Asp Asp Ser Asp Ile Leu Asn Ser Thr Ala Ala 
    50                  55                  60                  


Asp Glu Val Thr Ala His Leu Ala Ala Ala Gly Pro Val Gly Met Ala 
65                  70                  75                  80  


Ala Ala Ala Ala Val Ala Thr Gly Lys Lys Arg Lys Arg Pro His Val 
                85                  90                  95      


Phe Glu Ser Asn Pro Ser Ile Arg Lys Arg Gln Gln Thr Arg Leu Leu 
            100                 105                 110         


Arg Lys Leu Arg Ala Thr Leu Asp Glu Tyr Thr Thr Arg Val Gly Gln 
        115                 120                 125             


Gln Ala Ile Val Leu Cys Ile Ser Pro Ser Lys Pro Asn Pro Val Phe 
    130                 135                 140                 


Lys Val Phe Gly Ala Ala Pro Leu Glu Asn Val Val Arg Lys Tyr Lys 
145                 150                 155                 160 


Ser Met Ile Leu Glu Asp Leu Glu Ser Ala Leu Ala Glu His Ala Pro 
                165                 170                 175     


Ala Pro Gln Glu Val Asn Ser Glu Leu Pro Pro Leu Thr Ile Asp Gly 
            180                 185                 190         


Ile Pro Val Ser Val Asp Lys Met Thr Gln Ala Gln Leu Arg Ala Phe 
        195                 200                 205             


Ile Pro Glu Met Leu Lys Tyr Ser Thr Gly Arg Gly Lys Pro Gly Trp 
    210                 215                 220                 


Gly Lys Glu Ser Cys Lys Pro Ile Trp Trp Pro Glu Asp Ile Pro Trp 
225                 230                 235                 240 


Ala Asn Val Arg Ser Asp Val Arg Thr Glu Glu Gln Lys Gln Arg Val 
                245                 250                 255     


Ser Trp Thr Gln Ala Leu Arg Thr Ile Val Lys Asn Cys Tyr Lys Gln 
            260                 265                 270         


His Gly Arg Glu Asp Leu Leu Tyr Ala Phe Glu Asp Gln Gln Thr Gln 
        275                 280                 285             


Thr Gln Ala Thr Ala Thr His Ser Ile Ala His Leu Val Pro Ser Gln 
    290                 295                 300                 


Thr Val Val Gln Thr Phe Ser Asn Pro Asp Gly Thr Val Ser Leu Ile 
305                 310                 315                 320 


Gln Val Gly Thr Gly Ala Thr Val Ala Thr Leu Ala Asp Ala Ser Glu 
                325                 330                 335     


Leu Pro Thr Thr Val Thr Val Ala Gln Val Asn Tyr Ser Ala Val Ala 
            340                 345                 350         


Asp Gly Glu Val Glu Gln Asn Trp Ala Thr Leu Gln Gly Gly Glu Met 
        355                 360                 365             


Thr Ile Gln Thr Thr Gln Ala Ser Glu Ala Thr Gln Ala Val Ala Ser 
    370                 375                 380                 


Leu Ala Glu Ala Ala Val Ala Ala Ser Gln Glu Met Gln Gln Gly Ala 
385                 390                 395                 400 


Thr Val Thr Met Ala Leu Asn Ser Glu Ala Ala Ala His Ala Val Ala 
                405                 410                 415     


Thr Leu Ala Glu Ala Thr Leu Gln Gly Gly Gly Gln Ile Val Leu Ser 
            420                 425                 430         


Gly Glu Thr Ala Ala Ala Val Gly Ala Leu Thr Gly Val Gln Asp Ala 
        435                 440                 445             


Asn Gly Leu Val Gln Ile Pro Val Ser Met Tyr Gln Thr Val Val Thr 
    450                 455                 460                 


Ser Leu Ala Gln Gly Asn Gly Pro Val Gln Val Ala Met Ala Pro Val 
465                 470                 475                 480 


Thr Thr Arg Ile Ser Asp Ser Ala Val Thr Met Asp Gly Gln Ala Val 
                485                 490                 495     


Glu Val Val Thr Leu Glu Gln 
            500             


<210>  4233
<211>  309
<212>  PRT
<213>  homo sapiens

<400>  4233

Met Asp Asp Lys Ala Phe Thr Lys Glu Leu Asp Gln Trp Val Glu Gln 
1               5                   10                  15      


Leu Asn Glu Cys Lys Gln Leu Asn Glu Asn Gln Val Arg Thr Leu Cys 
            20                  25                  30          


Glu Lys Ala Lys Glu Ile Leu Thr Lys Glu Ser Asn Val Gln Glu Val 
        35                  40                  45              


Arg Cys Pro Val Thr Val Cys Gly Asp Val His Gly Gln Phe His Asp 
    50                  55                  60                  


Leu Met Glu Leu Phe Arg Ile Gly Gly Lys Ser Pro Asp Thr Asn Tyr 
65                  70                  75                  80  


Leu Phe Met Gly Asp Tyr Val Asp Arg Gly Tyr Tyr Ser Val Glu Thr 
                85                  90                  95      


Val Thr Leu Leu Val Ala Leu Lys Val Arg Tyr Pro Glu Arg Ile Thr 
            100                 105                 110         


Ile Leu Arg Gly Asn His Glu Ser Arg Gln Ile Thr Gln Val Tyr Gly 
        115                 120                 125             


Phe Tyr Asp Glu Cys Leu Arg Lys Tyr Gly Asn Ala Asn Val Trp Lys 
    130                 135                 140                 


Tyr Phe Thr Asp Leu Phe Asp Tyr Leu Pro Leu Thr Ala Leu Val Asp 
145                 150                 155                 160 


Gly Gln Ile Phe Cys Leu His Gly Gly Leu Ser Pro Ser Ile Asp Thr 
                165                 170                 175     


Leu Asp His Ile Arg Ala Leu Asp Arg Leu Gln Glu Val Pro His Glu 
            180                 185                 190         


Gly Pro Met Cys Asp Leu Leu Trp Ser Asp Pro Asp Asp Arg Gly Gly 
        195                 200                 205             


Trp Gly Ile Ser Pro Arg Gly Ala Gly Tyr Thr Phe Gly Gln Asp Ile 
    210                 215                 220                 


Ser Glu Thr Phe Asn His Ala Asn Gly Leu Thr Leu Val Ser Arg Ala 
225                 230                 235                 240 


His Gln Leu Val Met Glu Gly Tyr Asn Trp Cys His Asp Arg Asn Val 
                245                 250                 255     


Val Thr Ile Phe Ser Ala Pro Asn Tyr Cys Tyr Arg Cys Gly Asn Gln 
            260                 265                 270         


Ala Ala Ile Met Glu Leu Asp Asp Thr Leu Lys Tyr Ser Phe Leu Gln 
        275                 280                 285             


Phe Asp Pro Ala Pro Arg Arg Gly Glu Pro His Val Thr Arg Arg Thr 
    290                 295                 300                 


Pro Asp Tyr Phe Leu 
305                 


<210>  4234
<211>  392
<212>  PRT
<213>  homo sapiens

<400>  4234

Met Ala Val Val Ala Ala Ala Ala Gly Trp Leu Leu Arg Leu Arg Ala 
1               5                   10                  15      


Ala Gly Ala Glu Gly His Trp Arg Arg Leu Pro Gly Ala Gly Leu Ala 
            20                  25                  30          


Arg Gly Phe Leu His Pro Ala Ala Thr Val Glu Asp Ala Ala Gln Arg 
        35                  40                  45              


Arg Gln Val Ala His Phe Thr Phe Gln Pro Asp Pro Glu Pro Arg Glu 
    50                  55                  60                  


Tyr Gly Gln Thr Gln Lys Met Asn Leu Phe Gln Ser Val Thr Ser Ala 
65                  70                  75                  80  


Leu Asp Asn Ser Leu Ala Lys Asp Pro Thr Ala Val Ile Phe Gly Glu 
                85                  90                  95      


Asp Val Ala Phe Gly Gly Val Phe Arg Cys Thr Val Gly Leu Arg Asp 
            100                 105                 110         


Lys Tyr Gly Lys Asp Arg Val Phe Asn Thr Pro Leu Cys Glu Gln Gly 
        115                 120                 125             


Ile Val Gly Phe Gly Ile Gly Ile Ala Val Thr Gly Ala Thr Ala Ile 
    130                 135                 140                 


Ala Glu Ile Gln Phe Ala Asp Tyr Ile Phe Pro Ala Phe Asp Gln Ile 
145                 150                 155                 160 


Val Asn Glu Ala Ala Lys Tyr Arg Tyr Arg Ser Gly Asp Leu Phe Asn 
                165                 170                 175     


Cys Gly Ser Leu Thr Ile Arg Ser Pro Trp Gly Cys Val Gly His Gly 
            180                 185                 190         


Ala Leu Tyr His Ser Gln Ser Pro Glu Ala Phe Phe Ala His Cys Pro 
        195                 200                 205             


Gly Ile Lys Val Val Ile Pro Arg Ser Pro Phe Gln Ala Lys Gly Leu 
    210                 215                 220                 


Leu Leu Ser Cys Ile Glu Asp Lys Asn Pro Cys Ile Phe Phe Glu Pro 
225                 230                 235                 240 


Lys Ile Leu Tyr Arg Ala Ala Ala Glu Glu Val Pro Ile Glu Pro Tyr 
                245                 250                 255     


Asn Ile Pro Leu Ser Gln Ala Glu Val Ile Gln Glu Gly Ser Asp Val 
            260                 265                 270         


Thr Leu Val Ala Trp Gly Thr Gln Val His Val Ile Arg Glu Val Ala 
        275                 280                 285             


Ser Met Ala Lys Glu Lys Leu Gly Val Ser Cys Glu Val Ile Asp Leu 
    290                 295                 300                 


Arg Thr Ile Ile Pro Trp Asp Val Asp Thr Ile Cys Lys Ser Val Ile 
305                 310                 315                 320 


Lys Thr Gly Arg Leu Leu Ile Ser His Glu Ala Pro Leu Thr Gly Gly 
                325                 330                 335     


Phe Ala Ser Glu Ile Ser Ser Thr Val Gln Glu Glu Cys Phe Leu Asn 
            340                 345                 350         


Leu Glu Ala Pro Ile Ser Arg Val Cys Gly Tyr Asp Thr Pro Phe Pro 
        355                 360                 365             


His Ile Phe Glu Pro Phe Tyr Ile Pro Asp Lys Trp Lys Cys Tyr Asp 
    370                 375                 380                 


Ala Leu Arg Lys Met Ile Asn Tyr 
385                 390         


<210>  4235
<211>  433
<212>  PRT
<213>  homo sapiens

<400>  4235

Met Ala Leu Arg Val Thr Arg Asn Ser Lys Ile Asn Ala Glu Asn Lys 
1               5                   10                  15      


Ala Lys Ile Asn Met Ala Gly Ala Lys Arg Val Pro Thr Ala Pro Ala 
            20                  25                  30          


Ala Thr Ser Lys Pro Gly Leu Arg Pro Arg Thr Ala Leu Gly Asp Ile 
        35                  40                  45              


Gly Asn Lys Val Ser Glu Gln Leu Gln Ala Lys Met Pro Met Lys Lys 
    50                  55                  60                  


Glu Ala Lys Pro Ser Ala Thr Gly Lys Val Ile Asp Lys Lys Leu Pro 
65                  70                  75                  80  


Lys Pro Leu Glu Lys Val Pro Met Leu Val Pro Val Pro Val Ser Glu 
                85                  90                  95      


Pro Val Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Val Lys Glu 
            100                 105                 110         


Glu Lys Leu Ser Pro Glu Pro Ile Leu Val Asp Thr Ala Ser Pro Ser 
        115                 120                 125             


Pro Met Glu Thr Ser Gly Cys Ala Pro Ala Glu Glu Asp Leu Cys Gln 
    130                 135                 140                 


Ala Phe Ser Asp Val Ile Leu Ala Val Asn Asp Val Asp Ala Glu Asp 
145                 150                 155                 160 


Gly Ala Asp Pro Asn Leu Cys Ser Glu Tyr Val Lys Asp Ile Tyr Ala 
                165                 170                 175     


Tyr Leu Arg Gln Leu Glu Glu Glu Gln Ala Val Arg Pro Lys Tyr Leu 
            180                 185                 190         


Leu Gly Arg Glu Val Thr Gly Asn Met Arg Ala Ile Leu Ile Asp Trp 
        195                 200                 205             


Leu Val Gln Val Gln Met Lys Phe Arg Leu Leu Gln Glu Thr Met Tyr 
    210                 215                 220                 


Met Thr Val Ser Ile Ile Asp Arg Phe Met Gln Asn Asn Cys Val Pro 
225                 230                 235                 240 


Lys Lys Met Leu Gln Leu Val Gly Val Thr Ala Met Phe Ile Ala Ser 
                245                 250                 255     


Lys Tyr Glu Glu Met Tyr Pro Pro Glu Ile Gly Asp Phe Ala Phe Val 
            260                 265                 270         


Thr Asp Asn Thr Tyr Thr Lys His Gln Ile Arg Gln Met Glu Met Lys 
        275                 280                 285             


Ile Leu Arg Ala Leu Asn Phe Gly Leu Gly Arg Pro Leu Pro Leu His 
    290                 295                 300                 


Phe Leu Arg Arg Ala Ser Lys Ile Gly Glu Val Asp Val Glu Gln His 
305                 310                 315                 320 


Thr Leu Ala Lys Tyr Leu Met Glu Leu Thr Met Leu Asp Tyr Asp Met 
                325                 330                 335     


Val His Phe Pro Pro Ser Gln Ile Ala Ala Gly Ala Phe Cys Leu Ala 
            340                 345                 350         


Leu Lys Ile Leu Asp Asn Gly Glu Trp Thr Pro Thr Leu Gln His Tyr 
        355                 360                 365             


Leu Ser Tyr Thr Glu Glu Ser Leu Leu Pro Val Met Gln His Leu Ala 
    370                 375                 380                 


Lys Asn Val Val Met Val Asn Gln Gly Leu Thr Lys His Met Thr Val 
385                 390                 395                 400 


Lys Asn Lys Tyr Ala Thr Ser Lys His Ala Lys Ile Ser Thr Leu Pro 
                405                 410                 415     


Gln Leu Asn Ser Ala Leu Val Gln Asp Leu Ala Lys Ala Val Ala Lys 
            420                 425                 430         


Val 
    


<210>  4236
<211>  1395
<212>  PRT
<213>  homo sapiens

<400>  4236

Met Asp Thr Lys Leu Met Cys Leu Leu Phe Phe Phe Ser Leu Pro Pro 
1               5                   10                  15      


Leu Leu Val Ser Asn His Thr Gly Arg Ile Lys Val Val Phe Thr Pro 
            20                  25                  30          


Ser Ile Cys Lys Val Thr Cys Thr Lys Gly Ser Cys Gln Asn Ser Cys 
        35                  40                  45              


Glu Lys Gly Asn Thr Thr Thr Leu Ile Ser Glu Asn Gly His Ala Ala 
    50                  55                  60                  


Asp Thr Leu Thr Ala Thr Asn Phe Arg Val Val Ile Cys His Leu Pro 
65                  70                  75                  80  


Cys Met Asn Gly Gly Gln Cys Ser Ser Arg Asp Lys Cys Gln Cys Pro 
                85                  90                  95      


Pro Asn Phe Thr Gly Lys Leu Cys Gln Ile Pro Val His Gly Ala Ser 
            100                 105                 110         


Val Pro Lys Leu Tyr Gln His Ser Gln Gln Pro Gly Lys Ala Leu Gly 
        115                 120                 125             


Thr His Val Ile His Ser Thr His Thr Leu Pro Leu Thr Val Thr Ser 
    130                 135                 140                 


Gln Gln Gly Val Lys Val Lys Phe Pro Pro Asn Ile Val Asn Ile His 
145                 150                 155                 160 


Val Lys His Pro Pro Glu Ala Ser Val Gln Ile His Gln Val Ser Arg 
                165                 170                 175     


Ile Asp Gly Pro Thr Gly Gln Lys Thr Lys Glu Ala Gln Pro Gly Gln 
            180                 185                 190         


Ser Gln Val Ser Tyr Gln Gly Leu Pro Val Gln Lys Thr Gln Thr Ile 
        195                 200                 205             


His Ser Thr Tyr Ser His Gln Gln Val Ile Pro His Val Tyr Pro Val 
    210                 215                 220                 


Ala Ala Lys Thr Gln Leu Gly Arg Cys Phe Gln Glu Thr Ile Gly Ser 
225                 230                 235                 240 


Gln Cys Gly Lys Ala Leu Pro Gly Leu Ser Lys Gln Glu Asp Cys Cys 
                245                 250                 255     


Gly Thr Val Gly Thr Ser Trp Gly Phe Asn Lys Cys Gln Lys Cys Pro 
            260                 265                 270         


Lys Lys Pro Ser Tyr His Gly Tyr Asn Gln Met Met Glu Cys Leu Pro 
        275                 280                 285             


Gly Tyr Lys Arg Val Asn Asn Thr Phe Cys Gln Asp Ile Asn Glu Cys 
    290                 295                 300                 


Gln Leu Gln Gly Val Cys Pro Asn Gly Glu Cys Leu Asn Thr Met Gly 
305                 310                 315                 320 


Ser Tyr Arg Cys Thr Cys Lys Ile Gly Phe Gly Pro Asp Pro Thr Phe 
                325                 330                 335     


Ser Ser Cys Val Pro Asp Pro Pro Val Ile Ser Glu Glu Lys Gly Pro 
            340                 345                 350         


Cys Tyr Arg Leu Val Ser Ser Gly Arg Gln Cys Met His Pro Leu Ser 
        355                 360                 365             


Val His Leu Thr Lys Gln Leu Cys Cys Cys Ser Val Gly Lys Ala Trp 
    370                 375                 380                 


Gly Pro His Cys Glu Lys Cys Pro Leu Pro Gly Thr Ala Ala Phe Lys 
385                 390                 395                 400 


Glu Ile Cys Pro Gly Gly Met Gly Tyr Thr Val Ser Gly Val His Arg 
                405                 410                 415     


Arg Arg Pro Ile His His His Val Gly Lys Gly Pro Val Phe Val Lys 
            420                 425                 430         


Pro Lys Asn Thr Gln Pro Val Ala Lys Ser Thr His Pro Pro Pro Leu 
        435                 440                 445             


Pro Ala Lys Glu Glu Pro Val Glu Ala Leu Thr Phe Ser Arg Glu His 
    450                 455                 460                 


Gly Pro Gly Val Ala Glu Pro Glu Val Ala Thr Ala Pro Pro Glu Lys 
465                 470                 475                 480 


Glu Ile Pro Ser Leu Asp Gln Glu Lys Thr Lys Leu Glu Pro Gly Gln 
                485                 490                 495     


Pro Gln Leu Ser Pro Gly Ile Ser Thr Ile His Leu His Pro Gln Phe 
            500                 505                 510         


Pro Val Val Ile Glu Lys Thr Ser Pro Pro Val Pro Val Glu Val Ala 
        515                 520                 525             


Pro Glu Ala Ser Thr Ser Ser Ala Ser Gln Val Ile Ala Pro Thr Gln 
    530                 535                 540                 


Val Thr Glu Ile Asn Glu Cys Thr Val Asn Pro Asp Ile Cys Gly Ala 
545                 550                 555                 560 


Gly His Cys Ile Asn Leu Pro Val Arg Tyr Thr Cys Ile Cys Tyr Glu 
                565                 570                 575     


Gly Tyr Arg Phe Ser Glu Gln Gln Arg Lys Cys Val Asp Ile Asp Glu 
            580                 585                 590         


Cys Thr Gln Val Gln His Leu Cys Ser Gln Gly Arg Cys Glu Asn Thr 
        595                 600                 605             


Glu Gly Ser Phe Leu Cys Ile Cys Pro Ala Gly Phe Met Ala Ser Glu 
    610                 615                 620                 


Glu Gly Thr Asn Cys Ile Asp Val Asp Glu Cys Leu Arg Pro Asp Val 
625                 630                 635                 640 


Cys Gly Glu Gly His Cys Val Asn Thr Val Gly Ala Phe Arg Cys Glu 
                645                 650                 655     


Tyr Cys Asp Ser Gly Tyr Arg Met Thr Gln Arg Gly Arg Cys Glu Asp 
            660                 665                 670         


Ile Asp Glu Cys Leu Asn Pro Ser Thr Cys Pro Asp Glu Gln Cys Val 
        675                 680                 685             


Asn Ser Pro Gly Ser Tyr Gln Cys Val Pro Cys Thr Glu Gly Phe Arg 
    690                 695                 700                 


Gly Trp Asn Gly Gln Cys Leu Asp Val Asp Glu Cys Leu Glu Pro Asn 
705                 710                 715                 720 


Val Cys Ala Asn Gly Asp Cys Ser Asn Leu Glu Gly Ser Tyr Met Cys 
                725                 730                 735     


Ser Cys His Lys Gly Tyr Thr Arg Thr Pro Asp His Lys His Cys Arg 
            740                 745                 750         


Asp Ile Asp Glu Cys Gln Gln Gly Asn Leu Cys Val Asn Gly Gln Cys 
        755                 760                 765             


Lys Asn Thr Glu Gly Ser Phe Arg Cys Thr Cys Gly Gln Gly Tyr Gln 
    770                 775                 780                 


Leu Ser Ala Ala Lys Asp Gln Cys Glu Asp Ile Asp Glu Cys Gln His 
785                 790                 795                 800 


Arg His Leu Cys Ala His Gly Gln Cys Arg Asn Thr Glu Gly Ser Phe 
                805                 810                 815     


Gln Cys Val Cys Asp Gln Gly Tyr Arg Ala Ser Gly Leu Gly Asp His 
            820                 825                 830         


Cys Glu Asp Ile Asn Glu Cys Leu Glu Asp Lys Ser Val Cys Gln Arg 
        835                 840                 845             


Gly Asp Cys Ile Asn Thr Ala Gly Ser Tyr Asp Cys Thr Cys Pro Asp 
    850                 855                 860                 


Gly Phe Gln Leu Asp Asp Asn Lys Thr Cys Gln Asp Ile Asn Glu Cys 
865                 870                 875                 880 


Glu His Pro Gly Leu Cys Gly Pro Gln Gly Glu Cys Leu Asn Thr Glu 
                885                 890                 895     


Gly Ser Phe His Cys Val Cys Gln Gln Gly Phe Ser Ile Ser Ala Asp 
            900                 905                 910         


Gly Arg Thr Cys Glu Asp Ile Asp Glu Cys Val Asn Asn Thr Val Cys 
        915                 920                 925             


Asp Ser His Gly Phe Cys Asp Asn Thr Ala Gly Ser Phe Arg Cys Leu 
    930                 935                 940                 


Cys Tyr Gln Gly Phe Gln Ala Pro Gln Asp Gly Gln Gly Cys Val Asp 
945                 950                 955                 960 


Val Asn Glu Cys Glu Leu Leu Ser Gly Val Cys Gly Glu Ala Phe Cys 
                965                 970                 975     


Glu Asn Val Glu Gly Ser Phe Leu Cys Val Cys Ala Asp Glu Asn Gln 
            980                 985                 990         


Glu Tyr Ser Pro Met Thr Gly Gln  Cys Arg Ser Arg Thr  Ser Thr Asp 
        995                 1000                 1005             


Leu Asp  Val Asp Val Asp Gln  Pro Lys Glu Glu Lys  Lys Glu Cys 
    1010                 1015                 1020             


Tyr Tyr  Asn Leu Asn Asp Ala  Ser Leu Cys Asp Asn  Val Leu Ala 
    1025                 1030                 1035             


Pro Asn  Val Thr Lys Gln Glu  Cys Cys Cys Thr Ser  Gly Ala Gly 
    1040                 1045                 1050             


Trp Gly  Asp Asn Cys Glu Ile  Phe Pro Cys Pro Val  Leu Gly Thr 
    1055                 1060                 1065             


Ala Glu  Phe Thr Glu Met Cys  Pro Lys Gly Lys Gly  Phe Val Pro 
    1070                 1075                 1080             


Ala Gly  Glu Ser Ser Ser Glu  Ala Gly Gly Glu Asn  Tyr Lys Asp 
    1085                 1090                 1095             


Ala Asp  Glu Cys Leu Leu Phe  Gly Gln Glu Ile Cys  Lys Asn Gly 
    1100                 1105                 1110             


Phe Cys  Leu Asn Thr Arg Pro  Gly Tyr Glu Cys Tyr  Cys Lys Gln 
    1115                 1120                 1125             


Gly Thr  Tyr Tyr Asp Pro Val  Lys Leu Gln Cys Phe  Asp Met Asp 
    1130                 1135                 1140             


Glu Cys  Gln Asp Pro Ser Ser  Cys Ile Asp Gly Gln  Cys Val Asn 
    1145                 1150                 1155             


Thr Glu  Gly Ser Tyr Asn Cys  Phe Cys Thr His Pro  Met Val Leu 
    1160                 1165                 1170             


Asp Ala  Ser Glu Lys Arg Cys  Ile Arg Pro Ala Glu  Ser Asn Glu 
    1175                 1180                 1185             


Gln Ile  Glu Glu Thr Asp Val  Tyr Gln Asp Leu Cys  Trp Glu His 
    1190                 1195                 1200             


Leu Ser  Asp Glu Tyr Val Cys  Ser Arg Pro Leu Val  Gly Lys Gln 
    1205                 1210                 1215             


Thr Thr  Tyr Thr Glu Cys Cys  Cys Leu Tyr Gly Glu  Ala Trp Gly 
    1220                 1225                 1230             


Met Gln  Cys Ala Leu Cys Pro  Leu Lys Asp Ser Asp  Asp Tyr Ala 
    1235                 1240                 1245             


Gln Leu  Cys Asn Ile Pro Val  Thr Gly Arg Arg Gln  Pro Tyr Gly 
    1250                 1255                 1260             


Arg Asp  Ala Leu Val Asp Phe  Ser Glu Gln Tyr Thr  Pro Glu Ala 
    1265                 1270                 1275             


Asp Pro  Tyr Phe Ile Gln Asp  Arg Phe Leu Asn Ser  Phe Glu Glu 
    1280                 1285                 1290             


Leu Gln  Ala Glu Glu Cys Gly  Ile Leu Asn Gly Cys  Glu Asn Gly 
    1295                 1300                 1305             


Arg Cys  Val Arg Val Gln Glu  Gly Tyr Thr Cys Asp  Cys Phe Asp 
    1310                 1315                 1320             


Gly Tyr  His Leu Asp Thr Ala  Lys Met Thr Cys Val  Asp Val Asn 
    1325                 1330                 1335             


Glu Cys  Asp Glu Leu Asn Asn  Arg Met Ser Leu Cys  Lys Asn Ala 
    1340                 1345                 1350             


Lys Cys  Ile Asn Thr Asp Gly  Ser Tyr Lys Cys Leu  Cys Leu Pro 
    1355                 1360                 1365             


Gly Tyr  Val Pro Ser Asp Lys  Pro Asn Tyr Cys Thr  Pro Leu Asn 
    1370                 1375                 1380             


Thr Ala  Leu Asn Leu Glu Lys  Asp Ser Asp Leu Glu  
    1385                 1390                 1395 


<210>  4237
<211>  1353
<212>  PRT
<213>  homo sapiens

<400>  4237

Met Asp Thr Lys Leu Met Cys Leu Leu Phe Phe Phe Ser Leu Pro Pro 
1               5                   10                  15      


Leu Leu Val Ser Asn His Thr Gly Arg Ile Lys Val Val Phe Thr Pro 
            20                  25                  30          


Ser Ile Cys Lys Val Thr Cys Thr Lys Gly Ser Cys Gln Asn Ser Cys 
        35                  40                  45              


Glu Lys Gly Asn Thr Thr Thr Leu Ile Ser Glu Asn Gly His Ala Ala 
    50                  55                  60                  


Asp Thr Leu Thr Ala Thr Asn Phe Arg Val Val Ile Cys His Leu Pro 
65                  70                  75                  80  


Cys Met Asn Gly Gly Gln Cys Ser Ser Arg Asp Lys Cys Gln Cys Pro 
                85                  90                  95      


Pro Asn Phe Thr Gly Lys Leu Cys Gln Ile Pro Val His Gly Ala Ser 
            100                 105                 110         


Val Pro Lys Leu Tyr Gln His Ser Gln Gln Pro Gly Lys Ala Leu Gly 
        115                 120                 125             


Thr His Val Ile His Ser Thr His Thr Leu Pro Leu Thr Val Thr Ser 
    130                 135                 140                 


Gln Gln Gly Val Lys Val Lys Phe Pro Pro Asn Ile Val Asn Ile His 
145                 150                 155                 160 


Val Lys His Pro Pro Glu Ala Ser Val Gln Ile His Gln Val Ser Arg 
                165                 170                 175     


Ile Asp Gly Pro Thr Gly Gln Lys Thr Lys Glu Ala Gln Pro Gly Gln 
            180                 185                 190         


Ser Gln Val Ser Tyr Gln Gly Leu Pro Val Gln Lys Thr Gln Thr Ile 
        195                 200                 205             


His Ser Thr Tyr Ser His Gln Gln Val Ile Pro His Val Tyr Pro Val 
    210                 215                 220                 


Ala Ala Lys Thr Gln Leu Gly Arg Cys Phe Gln Glu Thr Ile Gly Ser 
225                 230                 235                 240 


Gln Cys Gly Lys Ala Leu Pro Gly Leu Ser Lys Gln Glu Asp Cys Cys 
                245                 250                 255     


Gly Thr Val Gly Thr Ser Trp Gly Phe Asn Lys Cys Gln Lys Cys Pro 
            260                 265                 270         


Lys Lys Pro Ser Tyr His Gly Tyr Asn Gln Met Met Glu Cys Leu Pro 
        275                 280                 285             


Gly Tyr Lys Arg Val Asn Asn Thr Phe Cys Gln Asp Ile Asn Glu Cys 
    290                 295                 300                 


Gln Leu Gln Gly Val Cys Pro Asn Gly Glu Cys Leu Asn Thr Met Gly 
305                 310                 315                 320 


Ser Tyr Arg Cys Thr Cys Lys Ile Gly Phe Gly Pro Asp Pro Thr Phe 
                325                 330                 335     


Ser Ser Cys Val Pro Asp Pro Pro Val Ile Ser Glu Glu Lys Gly Pro 
            340                 345                 350         


Cys Tyr Arg Leu Val Ser Ser Gly Arg Gln Cys Met His Pro Leu Ser 
        355                 360                 365             


Val His Leu Thr Lys Gln Leu Cys Cys Cys Ser Val Gly Lys Ala Trp 
    370                 375                 380                 


Gly Pro His Cys Glu Lys Cys Pro Leu Pro Gly Thr Ala Ala Phe Lys 
385                 390                 395                 400 


Glu Ile Cys Pro Gly Gly Met Gly Tyr Thr Val Ser Gly Val His Arg 
                405                 410                 415     


Arg Arg Pro Ile His His His Val Gly Lys Gly Pro Val Phe Val Lys 
            420                 425                 430         


Pro Lys Asn Thr Gln Pro Val Ala Lys Ser Thr His Pro Pro Pro Leu 
        435                 440                 445             


Pro Ala Lys Glu Glu Pro Val Glu Ala Leu Thr Phe Ser Arg Glu His 
    450                 455                 460                 


Gly Pro Gly Val Ala Glu Pro Glu Val Ala Thr Ala Pro Pro Glu Lys 
465                 470                 475                 480 


Glu Ile Pro Ser Leu Asp Gln Glu Lys Thr Lys Leu Glu Pro Gly Gln 
                485                 490                 495     


Pro Gln Leu Ser Pro Gly Ile Ser Thr Ile His Leu His Pro Gln Phe 
            500                 505                 510         


Pro Val Val Ile Glu Lys Thr Ser Pro Pro Val Pro Val Glu Val Ala 
        515                 520                 525             


Pro Glu Ala Ser Thr Ser Ser Ala Ser Gln Val Ile Ala Pro Thr Gln 
    530                 535                 540                 


Val Thr Glu Ile Asn Glu Cys Thr Val Asn Pro Asp Ile Cys Gly Ala 
545                 550                 555                 560 


Gly His Cys Ile Asn Leu Pro Val Arg Tyr Thr Cys Ile Cys Tyr Glu 
                565                 570                 575     


Gly Tyr Arg Phe Ser Glu Gln Gln Arg Lys Cys Val Asp Ile Asp Glu 
            580                 585                 590         


Cys Thr Gln Val Gln His Leu Cys Ser Gln Gly Arg Cys Glu Asn Thr 
        595                 600                 605             


Glu Gly Ser Phe Leu Cys Ile Cys Pro Ala Gly Phe Met Ala Ser Glu 
    610                 615                 620                 


Glu Gly Thr Asn Cys Ile Asp Val Asp Glu Cys Leu Arg Pro Asp Val 
625                 630                 635                 640 


Cys Gly Glu Gly His Cys Val Asn Thr Val Gly Ala Phe Arg Cys Glu 
                645                 650                 655     


Tyr Cys Asp Ser Gly Tyr Arg Met Thr Gln Arg Gly Arg Cys Glu Asp 
            660                 665                 670         


Ile Asp Glu Cys Leu Asn Pro Ser Thr Cys Pro Asp Glu Gln Cys Val 
        675                 680                 685             


Asn Ser Pro Gly Ser Tyr Gln Cys Val Pro Cys Thr Glu Gly Phe Arg 
    690                 695                 700                 


Gly Trp Asn Gly Gln Cys Leu Asp Val Asp Glu Cys Leu Glu Pro Asn 
705                 710                 715                 720 


Val Cys Ala Asn Gly Asp Cys Ser Asn Leu Glu Gly Ser Tyr Met Cys 
                725                 730                 735     


Ser Cys His Lys Gly Tyr Thr Arg Thr Pro Asp His Lys His Cys Arg 
            740                 745                 750         


Asp Ile Asp Glu Cys Gln Gln Gly Asn Leu Cys Val Asn Gly Gln Cys 
        755                 760                 765             


Lys Asn Thr Glu Gly Ser Phe Arg Cys Thr Cys Gly Gln Gly Tyr Gln 
    770                 775                 780                 


Leu Ser Ala Ala Lys Asp Gln Cys Glu Asp Ile Asp Glu Cys Gln His 
785                 790                 795                 800 


Arg His Leu Cys Ala His Gly Gln Cys Arg Asn Thr Glu Gly Ser Phe 
                805                 810                 815     


Gln Cys Val Cys Asp Gln Gly Tyr Arg Ala Ser Gly Leu Gly Asp His 
            820                 825                 830         


Cys Glu Asp Ile Asn Glu Cys Leu Glu Asp Lys Ser Val Cys Gln Arg 
        835                 840                 845             


Gly Asp Cys Ile Asn Thr Ala Gly Ser Tyr Asp Cys Thr Cys Pro Asp 
    850                 855                 860                 


Gly Phe Gln Leu Asp Asp Asn Lys Thr Cys Gln Asp Ile Asn Glu Cys 
865                 870                 875                 880 


Glu His Pro Gly Leu Cys Gly Pro Gln Gly Glu Cys Leu Asn Thr Glu 
                885                 890                 895     


Gly Ser Phe His Cys Val Cys Gln Gln Gly Phe Ser Ile Ser Ala Asp 
            900                 905                 910         


Gly Arg Thr Cys Glu Asp Val Asn Glu Cys Glu Leu Leu Ser Gly Val 
        915                 920                 925             


Cys Gly Glu Ala Phe Cys Glu Asn Val Glu Gly Ser Phe Leu Cys Val 
    930                 935                 940                 


Cys Ala Asp Glu Asn Gln Glu Tyr Ser Pro Met Thr Gly Gln Cys Arg 
945                 950                 955                 960 


Ser Arg Thr Ser Thr Asp Leu Asp Val Asp Val Asp Gln Pro Lys Glu 
                965                 970                 975     


Glu Lys Lys Glu Cys Tyr Tyr Asn Leu Asn Asp Ala Ser Leu Cys Asp 
            980                 985                 990         


Asn Val Leu Ala Pro Asn Val Thr  Lys Gln Glu Cys Cys  Cys Thr Ser 
        995                 1000                 1005             


Gly Ala  Gly Trp Gly Asp Asn  Cys Glu Ile Phe Pro  Cys Pro Val 
    1010                 1015                 1020             


Leu Gly  Thr Ala Glu Phe Thr  Glu Met Cys Pro Lys  Gly Lys Gly 
    1025                 1030                 1035             


Phe Val  Pro Ala Gly Glu Ser  Ser Ser Glu Ala Gly  Gly Glu Asn 
    1040                 1045                 1050             


Tyr Lys  Asp Ala Asp Glu Cys  Leu Leu Phe Gly Gln  Glu Ile Cys 
    1055                 1060                 1065             


Lys Asn  Gly Phe Cys Leu Asn  Thr Arg Pro Gly Tyr  Glu Cys Tyr 
    1070                 1075                 1080             


Cys Lys  Gln Gly Thr Tyr Tyr  Asp Pro Val Lys Leu  Gln Cys Phe 
    1085                 1090                 1095             


Asp Met  Asp Glu Cys Gln Asp  Pro Ser Ser Cys Ile  Asp Gly Gln 
    1100                 1105                 1110             


Cys Val  Asn Thr Glu Gly Ser  Tyr Asn Cys Phe Cys  Thr His Pro 
    1115                 1120                 1125             


Met Val  Leu Asp Ala Ser Glu  Lys Arg Cys Ile Arg  Pro Ala Glu 
    1130                 1135                 1140             


Ser Asn  Glu Gln Ile Glu Glu  Thr Asp Val Tyr Gln  Asp Leu Cys 
    1145                 1150                 1155             


Trp Glu  His Leu Ser Asp Glu  Tyr Val Cys Ser Arg  Pro Leu Val 
    1160                 1165                 1170             


Gly Lys  Gln Thr Thr Tyr Thr  Glu Cys Cys Cys Leu  Tyr Gly Glu 
    1175                 1180                 1185             


Ala Trp  Gly Met Gln Cys Ala  Leu Cys Pro Leu Lys  Asp Ser Asp 
    1190                 1195                 1200             


Asp Tyr  Ala Gln Leu Cys Asn  Ile Pro Val Thr Gly  Arg Arg Gln 
    1205                 1210                 1215             


Pro Tyr  Gly Arg Asp Ala Leu  Val Asp Phe Ser Glu  Gln Tyr Thr 
    1220                 1225                 1230             


Pro Glu  Ala Asp Pro Tyr Phe  Ile Gln Asp Arg Phe  Leu Asn Ser 
    1235                 1240                 1245             


Phe Glu  Glu Leu Gln Ala Glu  Glu Cys Gly Ile Leu  Asn Gly Cys 
    1250                 1255                 1260             


Glu Asn  Gly Arg Cys Val Arg  Val Gln Glu Gly Tyr  Thr Cys Asp 
    1265                 1270                 1275             


Cys Phe  Asp Gly Tyr His Leu  Asp Thr Ala Lys Met  Thr Cys Val 
    1280                 1285                 1290             


Asp Val  Asn Glu Cys Asp Glu  Leu Asn Asn Arg Met  Ser Leu Cys 
    1295                 1300                 1305             


Lys Asn  Ala Lys Cys Ile Asn  Thr Asp Gly Ser Tyr  Lys Cys Leu 
    1310                 1315                 1320             


Cys Leu  Pro Gly Tyr Val Pro  Ser Asp Lys Pro Asn  Tyr Cys Thr 
    1325                 1330                 1335             


Pro Leu  Asn Thr Ala Leu Asn  Leu Glu Lys Asp Ser  Asp Leu Glu 
    1340                 1345                 1350             


<210>  4238
<211>  323
<212>  PRT
<213>  homo sapiens

<400>  4238

Met Asp Ser Asp Ala Ser Leu Val Ser Ser Arg Pro Ser Ser Pro Glu 
1               5                   10                  15      


Pro Asp Asp Leu Phe Leu Pro Ala Arg Ser Lys Gly Ser Ser Gly Ser 
            20                  25                  30          


Ala Phe Thr Gly Gly Thr Val Ser Ser Ser Thr Pro Ser Asp Cys Pro 
        35                  40                  45              


Pro Glu Leu Ser Ala Glu Leu Arg Gly Ala Met Gly Ser Ala Gly Ala 
    50                  55                  60                  


His Pro Gly Asp Lys Leu Gly Gly Ser Gly Phe Lys Ser Ser Ser Ser 
65                  70                  75                  80  


Ser Thr Ser Ser Ser Thr Ser Ser Ala Ala Ala Ser Ser Thr Lys Lys 
                85                  90                  95      


Asp Lys Lys Gln Met Thr Glu Pro Glu Leu Gln Gln Leu Arg Leu Lys 
            100                 105                 110         


Ile Asn Ser Arg Glu Arg Lys Arg Met His Asp Leu Asn Ile Ala Met 
        115                 120                 125             


Asp Gly Leu Arg Glu Val Met Pro Tyr Ala His Gly Pro Ser Val Arg 
    130                 135                 140                 


Lys Leu Ser Lys Ile Ala Thr Leu Leu Leu Ala Arg Asn Tyr Ile Leu 
145                 150                 155                 160 


Met Leu Thr Asn Ser Leu Glu Glu Met Lys Arg Leu Val Ser Glu Ile 
                165                 170                 175     


Tyr Gly Gly His His Ala Gly Phe His Pro Ser Ala Cys Gly Gly Leu 
            180                 185                 190         


Ala His Ser Ala Pro Leu Pro Ala Ala Thr Ala His Pro Ala Ala Ala 
        195                 200                 205             


Ala His Ala Ala His His Pro Ala Val His His Pro Ile Leu Pro Pro 
    210                 215                 220                 


Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Val Ser Ser 
225                 230                 235                 240 


Ala Ser Leu Pro Gly Ser Gly Leu Pro Ser Val Gly Ser Ile Arg Pro 
                245                 250                 255     


Pro His Gly Leu Leu Lys Ser Pro Ser Ala Ala Ala Ala Ala Pro Leu 
            260                 265                 270         


Gly Gly Gly Gly Gly Gly Ser Gly Ala Ser Gly Gly Phe Gln His Trp 
        275                 280                 285             


Gly Gly Met Pro Cys Pro Cys Ser Met Cys Gln Val Pro Pro Pro His 
    290                 295                 300                 


His His Val Ser Ala Met Gly Ala Gly Ser Leu Pro Arg Leu Thr Ser 
305                 310                 315                 320 


Asp Ala Lys 
            


<210>  4239
<211>  258
<212>  PRT
<213>  homo sapiens

<400>  4239

Met Leu Cys Gly Arg Pro Arg Ser Ser Ser Asp Asn Arg Asn Phe Leu 
1               5                   10                  15      


Arg Glu Arg Ala Gly Leu Ser Ser Ala Ala Val Gln Thr Arg Ile Gly 
            20                  25                  30          


Asn Ser Ala Ala Ser Arg Arg Ser Pro Ala Ala Arg Pro Pro Val Pro 
        35                  40                  45              


Ala Pro Pro Ala Leu Pro Arg Gly Arg Pro Gly Thr Glu Gly Ser Thr 
    50                  55                  60                  


Ser Leu Ser Ala Pro Ala Val Leu Val Val Ala Val Ala Val Val Val 
65                  70                  75                  80  


Val Val Val Ser Ala Val Ala Trp Ala Met Ala Asn Tyr Ile His Val 
                85                  90                  95      


Pro Pro Gly Ser Pro Glu Val Pro Lys Leu Asn Val Thr Val Gln Asp 
            100                 105                 110         


Gln Glu Glu His Arg Cys Arg Glu Gly Ala Leu Ser Leu Leu Gln His 
        115                 120                 125             


Leu Arg Pro His Trp Asp Pro Gln Glu Val Thr Leu Gln Leu Phe Thr 
    130                 135                 140                 


Asp Gly Ile Thr Asn Lys Leu Ile Gly Cys Tyr Val Gly Asn Thr Met 
145                 150                 155                 160 


Glu Asp Val Val Leu Val Arg Ile Tyr Gly Asn Lys Thr Glu Leu Leu 
                165                 170                 175     


Val Asp Arg Asp Glu Glu Val Lys Ser Phe Arg Val Leu Gln Ala His 
            180                 185                 190         


Gly Cys Ala Pro Gln Leu Tyr Cys Thr Phe Asn Asn Gly Leu Cys Tyr 
        195                 200                 205             


Glu Phe Ile Gln Gly Glu Ala Leu Asp Pro Lys His Val Cys Asn Pro 
    210                 215                 220                 


Ala Ile Phe Ser Leu Ser Ser Leu Thr Leu Cys Lys Gly Lys Thr Thr 
225                 230                 235                 240 


Arg Cys Phe Gly Leu Thr Gly Cys Arg Gly Ser Arg Leu Leu Leu Ser 
                245                 250                 255     


Phe Phe 
        


<210>  4240
<211>  1217
<212>  PRT
<213>  homo sapiens

<400>  4240

Met Tyr Ile Lys Gln Val Ile Ile Gln Gly Phe Arg Ser Tyr Arg Asp 
1               5                   10                  15      


Gln Thr Ile Val Asp Pro Phe Ser Ser Lys His Asn Val Ile Val Gly 
            20                  25                  30          


Arg Asn Gly Ser Gly Lys Ser Asn Phe Phe Tyr Ala Ile Gln Phe Val 
        35                  40                  45              


Leu Ser Asp Glu Phe Ser His Leu Arg Pro Glu Gln Arg Leu Ala Leu 
    50                  55                  60                  


Leu His Glu Gly Thr Gly Pro Arg Val Ile Ser Ala Phe Val Glu Ile 
65                  70                  75                  80  


Ile Phe Asp Asn Ser Asp Asn Arg Leu Pro Ile Asp Lys Glu Glu Val 
                85                  90                  95      


Ser Leu Arg Arg Val Ile Gly Ala Lys Lys Asp Gln Tyr Phe Leu Asp 
            100                 105                 110         


Lys Lys Met Val Thr Lys Asn Asp Val Met Asn Leu Leu Glu Ser Ala 
        115                 120                 125             


Gly Phe Ser Arg Ser Asn Pro Tyr Tyr Ile Val Lys Gln Gly Lys Ile 
    130                 135                 140                 


Asn Gln Met Ala Thr Ala Pro Asp Ser Gln Arg Leu Lys Leu Leu Arg 
145                 150                 155                 160 


Glu Val Ala Gly Thr Arg Val Tyr Asp Glu Arg Lys Glu Glu Ser Ile 
                165                 170                 175     


Ser Leu Met Lys Glu Thr Glu Gly Lys Arg Glu Lys Ile Asn Glu Leu 
            180                 185                 190         


Leu Lys Tyr Ile Glu Glu Arg Leu His Thr Leu Glu Glu Glu Lys Glu 
        195                 200                 205             


Glu Leu Ala Gln Tyr Gln Lys Trp Asp Lys Met Arg Arg Ala Leu Glu 
    210                 215                 220                 


Tyr Thr Ile Tyr Asn Gln Glu Leu Asn Glu Thr Arg Ala Lys Leu Asp 
225                 230                 235                 240 


Glu Leu Ser Ala Lys Arg Glu Thr Ser Gly Glu Lys Ser Arg Gln Leu 
                245                 250                 255     


Arg Asp Ala Gln Gln Asp Ala Arg Asp Lys Met Glu Asp Ile Glu Arg 
            260                 265                 270         


Gln Val Arg Glu Leu Lys Thr Lys Ile Ser Ala Met Lys Glu Glu Lys 
        275                 280                 285             


Glu Gln Leu Ser Ala Glu Arg Gln Glu Gln Ile Lys Gln Arg Thr Lys 
    290                 295                 300                 


Leu Glu Leu Lys Ala Lys Asp Leu Gln Asp Glu Leu Ala Gly Asn Ser 
305                 310                 315                 320 


Glu Gln Arg Lys Arg Leu Leu Lys Glu Arg Gln Lys Leu Leu Glu Lys 
                325                 330                 335     


Ile Glu Glu Lys Gln Lys Glu Leu Ala Glu Thr Glu Pro Lys Phe Asn 
            340                 345                 350         


Ser Val Lys Glu Lys Glu Glu Arg Gly Ile Ala Arg Leu Ala Gln Ala 
        355                 360                 365             


Thr Gln Glu Arg Thr Asp Leu Tyr Ala Lys Gln Gly Arg Gly Ser Gln 
    370                 375                 380                 


Phe Thr Ser Lys Glu Glu Arg Asp Lys Trp Ile Lys Lys Glu Leu Lys 
385                 390                 395                 400 


Ser Leu Asp Gln Ala Ile Asn Asp Lys Lys Arg Gln Ile Ala Ala Ile 
                405                 410                 415     


His Lys Asp Leu Glu Asp Thr Glu Ala Asn Lys Glu Lys Asn Leu Glu 
            420                 425                 430         


Gln Tyr Asn Lys Leu Asp Gln Asp Leu Asn Glu Val Lys Ala Arg Val 
        435                 440                 445             


Glu Glu Leu Asp Arg Lys Tyr Tyr Glu Val Lys Asn Lys Lys Asp Glu 
    450                 455                 460                 


Leu Gln Ser Glu Arg Asn Tyr Leu Trp Arg Glu Glu Asn Ala Glu Gln 
465                 470                 475                 480 


Gln Ala Leu Ala Ala Lys Arg Glu Asp Leu Glu Lys Lys Gln Gln Leu 
                485                 490                 495     


Leu Arg Ala Ala Thr Gly Lys Ala Ile Leu Asn Gly Ile Asp Ser Ile 
            500                 505                 510         


Asn Lys Val Leu Asp His Phe Arg Arg Lys Gly Ile Asn Gln His Val 
        515                 520                 525             


Gln Asn Gly Tyr His Gly Ile Val Met Asn Asn Phe Glu Cys Glu Pro 
    530                 535                 540                 


Ala Phe Tyr Thr Cys Val Glu Val Thr Ala Gly Asn Arg Leu Phe Tyr 
545                 550                 555                 560 


His Ile Val Asp Ser Asp Glu Val Ser Thr Lys Ile Leu Met Glu Phe 
                565                 570                 575     


Asn Lys Met Asn Leu Pro Gly Glu Val Thr Phe Leu Pro Leu Asn Lys 
            580                 585                 590         


Leu Asp Val Arg Asp Thr Ala Tyr Pro Glu Thr Asn Asp Ala Ile Pro 
        595                 600                 605             


Met Ile Ser Lys Leu Arg Tyr Asn Pro Arg Phe Asp Lys Ala Phe Lys 
    610                 615                 620                 


His Val Phe Gly Lys Thr Leu Ile Cys Arg Ser Met Glu Val Ser Thr 
625                 630                 635                 640 


Gln Leu Ala Arg Ala Phe Thr Met Asp Cys Ile Thr Leu Glu Gly Asp 
                645                 650                 655     


Gln Val Ser His Arg Gly Ala Leu Thr Gly Gly Tyr Tyr Asp Thr Arg 
            660                 665                 670         


Lys Ser Arg Leu Glu Leu Gln Lys Asp Val Arg Lys Ala Glu Glu Glu 
        675                 680                 685             


Leu Gly Glu Leu Glu Ala Lys Leu Asn Glu Asn Leu Arg Arg Asn Ile 
    690                 695                 700                 


Glu Arg Ile Asn Asn Glu Ile Asp Gln Leu Met Asn Gln Met Gln Gln 
705                 710                 715                 720 


Ile Glu Thr Gln Gln Arg Lys Phe Lys Ala Ser Arg Asp Ser Ile Leu 
                725                 730                 735     


Ser Glu Met Lys Met Leu Lys Glu Lys Arg Gln Gln Ser Glu Lys Thr 
            740                 745                 750         


Phe Met Pro Lys Gln Arg Ser Leu Gln Ser Leu Glu Ala Ser Leu His 
        755                 760                 765             


Ala Met Glu Ser Thr Arg Glu Ser Leu Lys Ala Glu Leu Gly Thr Asp 
    770                 775                 780                 


Leu Leu Ser Gln Leu Ser Leu Glu Asp Gln Lys Arg Val Asp Ala Leu 
785                 790                 795                 800 


Asn Asp Glu Ile Arg Gln Leu Gln Gln Glu Asn Arg Gln Leu Leu Asn 
                805                 810                 815     


Glu Arg Ile Lys Leu Glu Gly Ile Ile Thr Arg Val Glu Thr Tyr Leu 
            820                 825                 830         


Asn Glu Asn Leu Arg Lys Arg Leu Asp Gln Val Glu Gln Glu Leu Asn 
        835                 840                 845             


Glu Leu Arg Glu Thr Glu Gly Gly Thr Val Leu Thr Ala Thr Thr Ser 
    850                 855                 860                 


Glu Leu Glu Ala Ile Asn Lys Arg Val Lys Asp Thr Met Ala Arg Ser 
865                 870                 875                 880 


Glu Asp Leu Asp Asn Ser Ile Asp Lys Thr Glu Ala Gly Ile Lys Glu 
                885                 890                 895     


Leu Gln Lys Ser Met Glu Arg Trp Lys Asn Met Glu Lys Glu His Met 
            900                 905                 910         


Asp Ala Ile Asn His Asp Thr Lys Glu Leu Glu Lys Met Thr Asn Arg 
        915                 920                 925             


Gln Gly Met Leu Leu Lys Lys Lys Glu Glu Cys Met Lys Lys Ile Arg 
    930                 935                 940                 


Glu Leu Gly Ser Leu Pro Gln Glu Ala Phe Glu Lys Tyr Gln Thr Leu 
945                 950                 955                 960 


Ser Leu Lys Gln Leu Phe Arg Lys Leu Glu Gln Cys Asn Thr Glu Leu 
                965                 970                 975     


Lys Lys Tyr Ser His Val Asn Lys Lys Ala Leu Asp Gln Phe Val Asn 
            980                 985                 990         


Phe Ser Glu Gln Lys Glu Lys Leu  Ile Lys Arg Gln Glu  Glu Leu Asp 
        995                 1000                 1005             


Arg Gly  Tyr Lys Ser Ile Met  Glu Leu Met Asn Val  Leu Glu Leu 
    1010                 1015                 1020             


Arg Lys  Tyr Glu Ala Ile Gln  Leu Thr Phe Lys Gln  Val Ser Lys 
    1025                 1030                 1035             


Asn Phe  Ser Glu Val Phe Gln  Lys Leu Val Pro Gly  Gly Lys Ala 
    1040                 1045                 1050             


Thr Leu  Val Met Lys Lys Gly  Asp Val Glu Gly Ser  Gln Ser Gln 
    1055                 1060                 1065             


Asp Glu  Gly Glu Gly Ser Gly  Glu Ser Glu Arg Gly  Ser Gly Ser 
    1070                 1075                 1080             


Gln Ser  Ser Val Pro Ser Val  Asp Gln Phe Thr Gly  Val Gly Ile 
    1085                 1090                 1095             


Arg Val  Ser Phe Thr Gly Lys  Gln Gly Glu Met Arg  Glu Met Gln 
    1100                 1105                 1110             


Gln Leu  Ser Gly Gly Gln Lys  Ser Leu Val Ala Leu  Ala Leu Ile 
    1115                 1120                 1125             


Phe Ala  Ile Gln Lys Cys Asp  Pro Ala Pro Phe Tyr  Leu Phe Asp 
    1130                 1135                 1140             


Glu Ile  Asp Gln Ala Leu Asp  Ala Gln His Arg Lys  Ala Val Ser 
    1145                 1150                 1155             


Asp Met  Ile Met Glu Leu Ala  Val His Ala Gln Phe  Ile Thr Thr 
    1160                 1165                 1170             


Thr Phe  Arg Pro Glu Leu Leu  Glu Ser Ala Asp Lys  Phe Tyr Gly 
    1175                 1180                 1185             


Val Lys  Phe Arg Asn Lys Val  Ser His Ile Asp Val  Ile Thr Ala 
    1190                 1195                 1200             


Glu Met  Ala Lys Asp Phe Val  Glu Asp Asp Thr Thr  His Gly 
    1205                 1210                 1215         


<210>  4241
<211>  484
<212>  PRT
<213>  homo sapiens

<400>  4241

Met Phe Pro Asn Ser Ile Leu Gly Arg Pro Pro Phe Thr Pro Asn His 
1               5                   10                  15      


Gln Gln His Asn Asn Phe Phe Thr Leu Ser Pro Thr Val Tyr Ser His 
            20                  25                  30          


Gln Gln Leu Ile Asp Ala Gln Phe Asn Phe Gln Asn Ala Asp Leu Ser 
        35                  40                  45              


Arg Ala Val Ser Leu Gln Gln Leu Thr Tyr Gly Asn Val Ser Pro Ile 
    50                  55                  60                  


Gln Thr Ser Ala Ser Pro Leu Phe Arg Gly Arg Lys Arg Leu Ser Asp 
65                  70                  75                  80  


Glu Lys Asn Leu Pro Leu Asp Gly Lys Arg Gln Arg Phe His Ser Pro 
                85                  90                  95      


His Gln Glu Pro Thr Val Val Asn Gln Ile Val Pro Leu Ser Gly Glu 
            100                 105                 110         


Arg Arg Tyr Ser Met Pro Pro Leu Phe His Thr His Tyr Val Pro Asp 
        115                 120                 125             


Ile Val Arg Cys Val Pro Pro Phe Arg Glu Ile Ala Phe Leu Glu Pro 
    130                 135                 140                 


Arg Glu Ile Thr Leu Pro Glu Ala Lys Asp Lys Leu Ser Gln Gln Ile 
145                 150                 155                 160 


Leu Glu Leu Phe Glu Thr Cys Gln Gln Gln Ile Ser Asp Leu Lys Lys 
                165                 170                 175     


Lys Glu Leu Cys Arg Thr Gln Leu Gln Arg Glu Ile Gln Leu Leu Phe 
            180                 185                 190         


Pro Gln Ser Arg Leu Phe Leu Val Gly Ser Ser Leu Asn Gly Phe Gly 
        195                 200                 205             


Thr Arg Ser Ser Asp Gly Asp Leu Cys Leu Val Val Lys Glu Glu Pro 
    210                 215                 220                 


Cys Phe Phe Gln Val Asn Gln Lys Thr Glu Ala Arg His Ile Leu Thr 
225                 230                 235                 240 


Leu Val His Lys His Phe Cys Thr Arg Leu Ser Gly Tyr Ile Glu Arg 
                245                 250                 255     


Pro Gln Leu Ile Arg Ala Lys Val Pro Ile Val Lys Phe Arg Asp Lys 
            260                 265                 270         


Val Ser Cys Val Glu Phe Asp Leu Asn Val Asn Asn Ile Val Gly Ile 
        275                 280                 285             


Arg Asn Thr Phe Leu Leu Arg Thr Tyr Ala Tyr Leu Glu Asn Arg Val 
    290                 295                 300                 


Arg Pro Leu Val Leu Val Ile Lys Lys Trp Ala Ser His His Gln Ile 
305                 310                 315                 320 


Asn Asp Ala Ser Arg Gly Thr Leu Ser Ser Tyr Ser Leu Val Leu Met 
                325                 330                 335     


Val Leu His Tyr Leu Gln Thr Leu Pro Glu Pro Ile Leu Pro Ser Leu 
            340                 345                 350         


Gln Lys Ile Tyr Pro Glu Ser Phe Ser Pro Ala Ile Gln Leu His Leu 
        355                 360                 365             


Val His Gln Ala Pro Cys Asn Val Pro Pro Tyr Leu Ser Lys Asn Glu 
    370                 375                 380                 


Ser Asn Leu Gly Asp Leu Leu Leu Gly Phe Leu Lys Tyr Tyr Ala Thr 
385                 390                 395                 400 


Glu Phe Asp Trp Asn Ser Gln Met Ile Ser Val Arg Glu Ala Lys Ala 
                405                 410                 415     


Ile Pro Arg Pro Asp Gly Ile Glu Trp Arg Asn Lys Tyr Ile Cys Val 
            420                 425                 430         


Glu Glu Pro Phe Asp Gly Thr Asn Thr Ala Arg Ala Val His Glu Lys 
        435                 440                 445             


Gln Lys Phe Asp Met Ile Lys Asp Gln Phe Leu Lys Ser Trp His Arg 
    450                 455                 460                 


Leu Lys Asn Lys Arg Asp Leu Asn Ser Ile Leu Pro Val Arg Ala Ala 
465                 470                 475                 480 


Val Leu Lys Arg 
                


<210>  4242
<211>  295
<212>  PRT
<213>  homo sapiens

<400>  4242

Met Ile Glu Val Leu Thr Thr Thr Asp Ser Gln Lys Leu Leu His Gln 
1               5                   10                  15      


Leu Asn Ala Leu Leu Glu Gln Glu Ser Arg Cys Gln Pro Lys Val Cys 
            20                  25                  30          


Gly Leu Arg Leu Ile Glu Ser Ala His Asp Asn Gly Leu Arg Met Thr 
        35                  40                  45              


Ala Arg Leu Arg Asp Phe Glu Val Lys Asp Leu Leu Ser Leu Thr Gln 
    50                  55                  60                  


Phe Phe Gly Phe Asp Thr Glu Thr Phe Ser Leu Ala Val Asn Leu Leu 
65                  70                  75                  80  


Asp Arg Phe Leu Ser Lys Met Lys Val Gln Pro Lys His Leu Gly Cys 
                85                  90                  95      


Val Gly Leu Ser Cys Phe Tyr Leu Ala Val Lys Ser Ile Glu Glu Glu 
            100                 105                 110         


Arg Asn Val Pro Leu Ala Thr Asp Leu Ile Arg Ile Ser Gln Tyr Arg 
        115                 120                 125             


Phe Thr Val Ser Asp Leu Met Arg Met Glu Lys Ile Val Leu Glu Lys 
    130                 135                 140                 


Val Cys Trp Lys Val Lys Ala Thr Thr Ala Phe Gln Phe Leu Gln Leu 
145                 150                 155                 160 


Tyr Tyr Ser Leu Leu Gln Glu Asn Leu Pro Leu Glu Arg Arg Asn Ser 
                165                 170                 175     


Ile Asn Phe Glu Arg Leu Glu Ala Gln Leu Lys Ala Cys His Cys Arg 
            180                 185                 190         


Ile Ile Phe Ser Lys Ala Lys Pro Ser Val Leu Ala Leu Ser Ile Ile 
        195                 200                 205             


Ala Leu Glu Ile Gln Ala Gln Lys Cys Val Glu Leu Thr Glu Gly Ile 
    210                 215                 220                 


Glu Cys Leu Gln Lys His Ser Lys Ile Asn Gly Arg Asp Leu Thr Phe 
225                 230                 235                 240 


Trp Gln Glu Leu Val Ser Lys Cys Leu Thr Glu Tyr Ser Ser Asn Lys 
                245                 250                 255     


Cys Ser Lys Pro Asn Val Gln Lys Leu Lys Trp Ile Val Ser Gly Arg 
            260                 265                 270         


Thr Ala Arg Gln Leu Lys His Ser Tyr Tyr Arg Ile Thr His Leu Pro 
        275                 280                 285             


Thr Ile Pro Glu Met Val Pro 
    290                 295 


<210>  4243
<211>  682
<212>  PRT
<213>  homo sapiens

<400>  4243

Met Ser Thr Pro Ala Val Pro Gln Asp Leu Gln Leu Pro Pro Ser Gln 
1               5                   10                  15      


Arg Ala Gln Ser Ala Phe Lys Glu Gln Arg Arg Gln Lys Leu Lys Glu 
            20                  25                  30          


His Leu Leu Arg Arg Lys Thr Leu Phe Ala Tyr Lys Gln Glu Asn Glu 
        35                  40                  45              


Met Leu Ser Ser Arg Asp Gln Arg Val Val Thr Ser Glu Asp Gln Val 
    50                  55                  60                  


Gln Glu Gly Thr Lys Val Leu Lys Leu Lys Thr Lys Met Ala Asp Lys 
65                  70                  75                  80  


Glu Asn Met Lys Arg Pro Ala Glu Ser Lys Asn Asn Thr Val Val Gly 
                85                  90                  95      


Lys His Cys Ile Pro Leu Lys Pro Ser Asn Glu Leu Thr Asn Ser Thr 
            100                 105                 110         


Val Val Ile Asp Thr His Lys Pro Lys Asp Ser Asn Gln Thr Pro His 
        115                 120                 125             


Leu Leu Leu Thr Glu Asp Asp Pro Gln Ser Gln His Met Thr Leu Ser 
    130                 135                 140                 


Gln Ala Phe His Leu Lys Asn Asn Ser Lys Lys Lys Gln Met Thr Thr 
145                 150                 155                 160 


Glu Lys Gln Lys Gln Asp Ala Asn Met Pro Lys Lys Pro Val Leu Gly 
                165                 170                 175     


Ser Tyr Arg Gly Gln Ile Val Gln Ser Lys Ile Asn Ser Phe Arg Lys 
            180                 185                 190         


Pro Leu Gln Val Lys Asp Glu Ser Ser Ala Ala Thr Lys Lys Leu Ser 
        195                 200                 205             


Ala Thr Ile Pro Lys Ala Thr Lys Pro Gln Pro Val Asn Thr Ser Ser 
    210                 215                 220                 


Val Thr Val Lys Ser Asn Arg Ser Ser Asn Met Thr Ala Thr Thr Lys 
225                 230                 235                 240 


Phe Val Ser Thr Thr Ser Gln Asn Thr Gln Leu Val Arg Pro Pro Ile 
                245                 250                 255     


Arg Ser His His Ser Asn Thr Arg Asp Thr Val Lys Gln Gly Ile Ser 
            260                 265                 270         


Arg Thr Ser Ala Asn Val Thr Ile Arg Lys Gly Pro His Glu Lys Glu 
        275                 280                 285             


Leu Leu Gln Ser Lys Thr Ala Leu Ser Ser Val Lys Thr Ser Ser Ser 
    290                 295                 300                 


Gln Gly Ile Ile Arg Asn Lys Thr Leu Ser Arg Ser Ile Ala Ser Glu 
305                 310                 315                 320 


Val Ile Ala Arg Pro Ala Ser Leu Ser Asn Asp Lys Leu Met Glu Lys 
                325                 330                 335     


Ser Glu Pro Val Asp Gln Arg Arg His Thr Ala Gly Lys Ala Ile Val 
            340                 345                 350         


Asp Ser Arg Ser Ala Gln Pro Lys Glu Thr Ser Glu Glu Arg Lys Ala 
        355                 360                 365             


Arg Leu Ser Glu Trp Lys Ala Gly Lys Gly Arg Val Leu Lys Arg Pro 
    370                 375                 380                 


Pro Asn Ser Val Val Thr Gln His Glu Pro Ala Gly Gln Asn Glu Lys 
385                 390                 395                 400 


Pro Val Gly Ser Phe Trp Thr Thr Met Ala Glu Glu Asp Glu Gln Arg 
                405                 410                 415     


Leu Phe Thr Glu Lys Val Asn Asn Thr Phe Ser Glu Cys Leu Asn Leu 
            420                 425                 430         


Ile Asn Glu Gly Cys Pro Lys Glu Asp Ile Leu Val Thr Leu Asn Asp 
        435                 440                 445             


Leu Ile Lys Asn Ile Pro Asp Ala Lys Lys Leu Val Lys Tyr Trp Ile 
    450                 455                 460                 


Cys Leu Ala Leu Ile Glu Pro Ile Thr Ser Pro Ile Glu Asn Ile Ile 
465                 470                 475                 480 


Ala Ile Tyr Glu Lys Ala Ile Leu Ala Gly Ala Gln Pro Ile Glu Glu 
                485                 490                 495     


Met Arg His Thr Ile Val Asp Ile Leu Thr Met Lys Ser Gln Glu Lys 
            500                 505                 510         


Ala Asn Leu Gly Glu Asn Met Glu Lys Ser Cys Ala Ser Lys Glu Glu 
        515                 520                 525             


Val Lys Glu Val Ser Ile Glu Asp Thr Gly Val Asp Val Asp Pro Glu 
    530                 535                 540                 


Lys Leu Glu Met Glu Ser Lys Leu His Arg Asn Leu Leu Phe Gln Asp 
545                 550                 555                 560 


Cys Glu Lys Glu Gln Asp Asn Lys Thr Lys Asp Pro Thr His Asp Val 
                565                 570                 575     


Lys Thr Pro Asn Thr Glu Thr Arg Thr Ser Cys Leu Ile Lys Tyr Asn 
            580                 585                 590         


Val Ser Thr Thr Pro Tyr Leu Gln Ser Val Lys Lys Lys Val Gln Phe 
        595                 600                 605             


Asp Gly Thr Asn Ser Ala Phe Lys Glu Leu Lys Phe Leu Thr Pro Val 
    610                 615                 620                 


Arg Arg Ser Arg Arg Leu Gln Glu Lys Thr Ser Lys Leu Pro Asp Met 
625                 630                 635                 640 


Leu Lys Asp His Tyr Pro Cys Val Ser Ser Leu Glu Gln Leu Thr Glu 
                645                 650                 655     


Leu Gly Arg Glu Thr Asp Ala Phe Val Cys Arg Pro Asn Ala Ala Leu 
            660                 665                 670         


Cys Arg Val Tyr Tyr Glu Ala Asp Thr Thr 
        675                 680         


<210>  4244
<211>  1366
<212>  PRT
<213>  homo sapiens

<400>  4244

Met Leu Ser Phe Val Asp Thr Arg Thr Leu Leu Leu Leu Ala Val Thr 
1               5                   10                  15      


Leu Cys Leu Ala Thr Cys Gln Ser Leu Gln Glu Glu Thr Val Arg Lys 
            20                  25                  30          


Gly Pro Ala Gly Asp Arg Gly Pro Arg Gly Glu Arg Gly Pro Pro Gly 
        35                  40                  45              


Pro Pro Gly Arg Asp Gly Glu Asp Gly Pro Thr Gly Pro Pro Gly Pro 
    50                  55                  60                  


Pro Gly Pro Pro Gly Pro Pro Gly Leu Gly Gly Asn Phe Ala Ala Gln 
65                  70                  75                  80  


Tyr Asp Gly Lys Gly Val Gly Leu Gly Pro Gly Pro Met Gly Leu Met 
                85                  90                  95      


Gly Pro Arg Gly Pro Pro Gly Ala Ala Gly Ala Pro Gly Pro Gln Gly 
            100                 105                 110         


Phe Gln Gly Pro Ala Gly Glu Pro Gly Glu Pro Gly Gln Thr Gly Pro 
        115                 120                 125             


Ala Gly Ala Arg Gly Pro Ala Gly Pro Pro Gly Lys Ala Gly Glu Asp 
    130                 135                 140                 


Gly His Pro Gly Lys Pro Gly Arg Pro Gly Glu Arg Gly Val Val Gly 
145                 150                 155                 160 


Pro Gln Gly Ala Arg Gly Phe Pro Gly Thr Pro Gly Leu Pro Gly Phe 
                165                 170                 175     


Lys Gly Ile Arg Gly His Asn Gly Leu Asp Gly Leu Lys Gly Gln Pro 
            180                 185                 190         


Gly Ala Pro Gly Val Lys Gly Glu Pro Gly Ala Pro Gly Glu Asn Gly 
        195                 200                 205             


Thr Pro Gly Gln Thr Gly Ala Arg Gly Leu Pro Gly Glu Arg Gly Arg 
    210                 215                 220                 


Val Gly Ala Pro Gly Pro Ala Gly Ala Arg Gly Ser Asp Gly Ser Val 
225                 230                 235                 240 


Gly Pro Val Gly Pro Ala Gly Pro Ile Gly Ser Ala Gly Pro Pro Gly 
                245                 250                 255     


Phe Pro Gly Ala Pro Gly Pro Lys Gly Glu Ile Gly Ala Val Gly Asn 
            260                 265                 270         


Ala Gly Pro Ala Gly Pro Ala Gly Pro Arg Gly Glu Val Gly Leu Pro 
        275                 280                 285             


Gly Leu Ser Gly Pro Val Gly Pro Pro Gly Asn Pro Gly Ala Asn Gly 
    290                 295                 300                 


Leu Thr Gly Ala Lys Gly Ala Ala Gly Leu Pro Gly Val Ala Gly Ala 
305                 310                 315                 320 


Pro Gly Leu Pro Gly Pro Arg Gly Ile Pro Gly Pro Val Gly Ala Ala 
                325                 330                 335     


Gly Ala Thr Gly Ala Arg Gly Leu Val Gly Glu Pro Gly Pro Ala Gly 
            340                 345                 350         


Ser Lys Gly Glu Ser Gly Asn Lys Gly Glu Pro Gly Ser Ala Gly Pro 
        355                 360                 365             


Gln Gly Pro Pro Gly Pro Ser Gly Glu Glu Gly Lys Arg Gly Pro Asn 
    370                 375                 380                 


Gly Glu Ala Gly Ser Ala Gly Pro Pro Gly Pro Pro Gly Leu Arg Gly 
385                 390                 395                 400 


Ser Pro Gly Ser Arg Gly Leu Pro Gly Ala Asp Gly Arg Ala Gly Val 
                405                 410                 415     


Met Gly Pro Pro Gly Ser Arg Gly Ala Ser Gly Pro Ala Gly Val Arg 
            420                 425                 430         


Gly Pro Asn Gly Asp Ala Gly Arg Pro Gly Glu Pro Gly Leu Met Gly 
        435                 440                 445             


Pro Arg Gly Leu Pro Gly Ser Pro Gly Asn Ile Gly Pro Ala Gly Lys 
    450                 455                 460                 


Glu Gly Pro Val Gly Leu Pro Gly Ile Asp Gly Arg Pro Gly Pro Ile 
465                 470                 475                 480 


Gly Pro Ala Gly Ala Arg Gly Glu Pro Gly Asn Ile Gly Phe Pro Gly 
                485                 490                 495     


Pro Lys Gly Pro Thr Gly Asp Pro Gly Lys Asn Gly Asp Lys Gly His 
            500                 505                 510         


Ala Gly Leu Ala Gly Ala Arg Gly Ala Pro Gly Pro Asp Gly Asn Asn 
        515                 520                 525             


Gly Ala Gln Gly Pro Pro Gly Pro Gln Gly Val Gln Gly Gly Lys Gly 
    530                 535                 540                 


Glu Gln Gly Pro Pro Gly Pro Pro Gly Phe Gln Gly Leu Pro Gly Pro 
545                 550                 555                 560 


Ser Gly Pro Ala Gly Glu Val Gly Lys Pro Gly Glu Arg Gly Leu His 
                565                 570                 575     


Gly Glu Phe Gly Leu Pro Gly Pro Ala Gly Pro Arg Gly Glu Arg Gly 
            580                 585                 590         


Pro Pro Gly Glu Ser Gly Ala Ala Gly Pro Thr Gly Pro Ile Gly Ser 
        595                 600                 605             


Arg Gly Pro Ser Gly Pro Pro Gly Pro Asp Gly Asn Lys Gly Glu Pro 
    610                 615                 620                 


Gly Val Val Gly Ala Val Gly Thr Ala Gly Pro Ser Gly Pro Ser Gly 
625                 630                 635                 640 


Leu Pro Gly Glu Arg Gly Ala Ala Gly Ile Pro Gly Gly Lys Gly Glu 
                645                 650                 655     


Lys Gly Glu Pro Gly Leu Arg Gly Glu Ile Gly Asn Pro Gly Arg Asp 
            660                 665                 670         


Gly Ala Arg Gly Ala Pro Gly Ala Val Gly Ala Pro Gly Pro Ala Gly 
        675                 680                 685             


Ala Thr Gly Asp Arg Gly Glu Ala Gly Ala Ala Gly Pro Ala Gly Pro 
    690                 695                 700                 


Ala Gly Pro Arg Gly Ser Pro Gly Glu Arg Gly Glu Val Gly Pro Ala 
705                 710                 715                 720 


Gly Pro Asn Gly Phe Ala Gly Pro Ala Gly Ala Ala Gly Gln Pro Gly 
                725                 730                 735     


Ala Lys Gly Glu Arg Gly Ala Lys Gly Pro Lys Gly Glu Asn Gly Val 
            740                 745                 750         


Val Gly Pro Thr Gly Pro Val Gly Ala Ala Gly Pro Ala Gly Pro Asn 
        755                 760                 765             


Gly Pro Pro Gly Pro Ala Gly Ser Arg Gly Asp Gly Gly Pro Pro Gly 
    770                 775                 780                 


Met Thr Gly Phe Pro Gly Ala Ala Gly Arg Thr Gly Pro Pro Gly Pro 
785                 790                 795                 800 


Ser Gly Ile Ser Gly Pro Pro Gly Pro Pro Gly Pro Ala Gly Lys Glu 
                805                 810                 815     


Gly Leu Arg Gly Pro Arg Gly Asp Gln Gly Pro Val Gly Arg Thr Gly 
            820                 825                 830         


Glu Val Gly Ala Val Gly Pro Pro Gly Phe Ala Gly Glu Lys Gly Pro 
        835                 840                 845             


Ser Gly Glu Ala Gly Thr Ala Gly Pro Pro Gly Thr Pro Gly Pro Gln 
    850                 855                 860                 


Gly Leu Leu Gly Ala Pro Gly Ile Leu Gly Leu Pro Gly Ser Arg Gly 
865                 870                 875                 880 


Glu Arg Gly Leu Pro Gly Val Ala Gly Ala Val Gly Glu Pro Gly Pro 
                885                 890                 895     


Leu Gly Ile Ala Gly Pro Pro Gly Ala Arg Gly Pro Pro Gly Ala Val 
            900                 905                 910         


Gly Ser Pro Gly Val Asn Gly Ala Pro Gly Glu Ala Gly Arg Asp Gly 
        915                 920                 925             


Asn Pro Gly Asn Asp Gly Pro Pro Gly Arg Asp Gly Gln Pro Gly His 
    930                 935                 940                 


Lys Gly Glu Arg Gly Tyr Pro Gly Asn Ile Gly Pro Val Gly Ala Ala 
945                 950                 955                 960 


Gly Ala Pro Gly Pro His Gly Pro Val Gly Pro Ala Gly Lys His Gly 
                965                 970                 975     


Asn Arg Gly Glu Thr Gly Pro Ser Gly Pro Val Gly Pro Ala Gly Ala 
            980                 985                 990         


Val Gly Pro Arg Gly Pro Ser Gly  Pro Gln Gly Ile Arg  Gly Asp Lys 
        995                 1000                 1005             


Gly Glu  Pro Gly Glu Lys Gly  Pro Arg Gly Leu Pro  Gly Leu Lys 
    1010                 1015                 1020             


Gly His  Asn Gly Leu Gln Gly  Leu Pro Gly Ile Ala  Gly His His 
    1025                 1030                 1035             


Gly Asp  Gln Gly Ala Pro Gly  Ser Val Gly Pro Ala  Gly Pro Arg 
    1040                 1045                 1050             


Gly Pro  Ala Gly Pro Ser Gly  Pro Ala Gly Lys Asp  Gly Arg Thr 
    1055                 1060                 1065             


Gly His  Pro Gly Thr Val Gly  Pro Ala Gly Ile Arg  Gly Pro Gln 
    1070                 1075                 1080             


Gly His  Gln Gly Pro Ala Gly  Pro Pro Gly Pro Pro  Gly Pro Pro 
    1085                 1090                 1095             


Gly Pro  Pro Gly Val Ser Gly  Gly Gly Tyr Asp Phe  Gly Tyr Asp 
    1100                 1105                 1110             


Gly Asp  Phe Tyr Arg Ala Asp  Gln Pro Arg Ser Ala  Pro Ser Leu 
    1115                 1120                 1125             


Arg Pro  Lys Asp Tyr Glu Val  Asp Ala Thr Leu Lys  Ser Leu Asn 
    1130                 1135                 1140             


Asn Gln  Ile Glu Thr Leu Leu  Thr Pro Glu Gly Ser  Arg Lys Asn 
    1145                 1150                 1155             


Pro Ala  Arg Thr Cys Arg Asp  Leu Arg Leu Ser His  Pro Glu Trp 
    1160                 1165                 1170             


Ser Ser  Gly Tyr Tyr Trp Ile  Asp Pro Asn Gln Gly  Cys Thr Met 
    1175                 1180                 1185             


Asp Ala  Ile Lys Val Tyr Cys  Asp Phe Ser Thr Gly  Glu Thr Cys 
    1190                 1195                 1200             


Ile Arg  Ala Gln Pro Glu Asn  Ile Pro Ala Lys Asn  Trp Tyr Arg 
    1205                 1210                 1215             


Ser Ser  Lys Asp Lys Lys His  Val Trp Leu Gly Glu  Thr Ile Asn 
    1220                 1225                 1230             


Ala Gly  Ser Gln Phe Glu Tyr  Asn Val Glu Gly Val  Thr Ser Lys 
    1235                 1240                 1245             


Glu Met  Ala Thr Gln Leu Ala  Phe Met Arg Leu Leu  Ala Asn Tyr 
    1250                 1255                 1260             


Ala Ser  Gln Asn Ile Thr Tyr  His Cys Lys Asn Ser  Ile Ala Tyr 
    1265                 1270                 1275             


Met Asp  Glu Glu Thr Gly Asn  Leu Lys Lys Ala Val  Ile Leu Gln 
    1280                 1285                 1290             


Gly Ser  Asn Asp Val Glu Leu  Val Ala Glu Gly Asn  Ser Arg Phe 
    1295                 1300                 1305             


Thr Tyr  Thr Val Leu Val Asp  Gly Cys Ser Lys Lys  Thr Asn Glu 
    1310                 1315                 1320             


Trp Gly  Lys Thr Ile Ile Glu  Tyr Lys Thr Asn Lys  Pro Ser Arg 
    1325                 1330                 1335             


Leu Pro  Phe Leu Asp Ile Ala  Pro Leu Asp Ile Gly  Gly Ala Asp 
    1340                 1345                 1350             


Gln Glu  Phe Phe Val Asp Ile  Gly Pro Val Cys Phe  Lys 
    1355                 1360                 1365     


<210>  4245
<211>  196
<212>  PRT
<213>  homo sapiens

<400>  4245

Met Phe Cys Glu Lys Ala Met Glu Leu Ile Arg Glu Leu His Arg Ala 
1               5                   10                  15      


Pro Glu Gly Gln Leu Pro Ala Phe Asn Glu Asp Gly Leu Arg Gln Val 
            20                  25                  30          


Leu Glu Glu Met Lys Ala Leu Tyr Glu Gln Asn Gln Ser Asp Val Asn 
        35                  40                  45              


Glu Ala Lys Ser Gly Gly Arg Ser Asp Leu Ile Pro Thr Ile Lys Phe 
    50                  55                  60                  


Arg His Cys Ser Leu Leu Arg Asn Arg Arg Cys Thr Val Ala Tyr Leu 
65                  70                  75                  80  


Tyr Asp Arg Leu Leu Arg Ile Arg Ala Leu Arg Trp Glu Tyr Gly Ser 
                85                  90                  95      


Val Leu Pro Asn Ala Leu Arg Phe His Met Ala Ala Glu Glu Met Glu 
            100                 105                 110         


Trp Phe Asn Asn Tyr Lys Arg Ser Leu Ala Thr Tyr Met Arg Ser Leu 
        115                 120                 125             


Gly Gly Asp Glu Gly Leu Asp Ile Thr Gln Asp Met Lys Pro Pro Lys 
    130                 135                 140                 


Ser Leu Tyr Ile Glu Val Arg Cys Leu Lys Asp Tyr Gly Glu Phe Glu 
145                 150                 155                 160 


Val Asp Asp Gly Thr Ser Val Leu Leu Lys Lys Asn Ser Gln His Phe 
                165                 170                 175     


Leu Pro Arg Trp Lys Cys Glu Gln Leu Ile Arg Gln Gly Val Leu Glu 
            180                 185                 190         


His Ile Leu Ser 
        195     


<210>  4246
<211>  559
<212>  PRT
<213>  homo sapiens

<400>  4246

Met Pro Leu Val Lys Arg Asn Ile Asp Pro Arg His Leu Cys His Thr 
1               5                   10                  15      


Ala Leu Pro Arg Gly Ile Lys Asn Glu Leu Glu Cys Val Thr Asn Ile 
            20                  25                  30          


Ser Leu Ala Asn Ile Ile Arg Gln Leu Ser Ser Leu Ser Lys Tyr Ala 
        35                  40                  45              


Glu Asp Ile Phe Gly Glu Leu Phe Asn Glu Ala His Ser Phe Ser Phe 
    50                  55                  60                  


Arg Val Asn Ser Leu Gln Glu Arg Val Asp Arg Leu Ser Val Ser Val 
65                  70                  75                  80  


Thr Gln Leu Asp Pro Lys Glu Glu Glu Leu Ser Leu Gln Asp Ile Thr 
                85                  90                  95      


Met Arg Lys Ala Phe Arg Ser Ser Thr Ile Gln Asp Gln Gln Leu Phe 
            100                 105                 110         


Asp Arg Lys Thr Leu Pro Ile Pro Leu Gln Glu Thr Tyr Asp Val Cys 
        115                 120                 125             


Glu Gln Pro Pro Pro Leu Asn Ile Leu Thr Pro Tyr Arg Asp Asp Gly 
    130                 135                 140                 


Lys Glu Gly Leu Lys Phe Tyr Thr Asn Pro Ser Tyr Phe Phe Asp Leu 
145                 150                 155                 160 


Trp Lys Glu Lys Met Leu Gln Asp Thr Glu Asp Lys Arg Lys Glu Lys 
                165                 170                 175     


Arg Lys Gln Lys Gln Lys Asn Leu Asp Arg Pro His Glu Pro Glu Lys 
            180                 185                 190         


Val Pro Arg Ala Pro His Asp Arg Arg Arg Glu Trp Gln Lys Leu Ala 
        195                 200                 205             


Gln Gly Pro Glu Leu Ala Glu Asp Asp Ala Asn Leu Leu His Lys His 
    210                 215                 220                 


Ile Glu Val Ala Asn Gly Pro Ala Ser His Phe Glu Thr Arg Pro Gln 
225                 230                 235                 240 


Thr Tyr Val Asp His Met Asp Gly Ser Tyr Ser Leu Ser Ala Leu Pro 
                245                 250                 255     


Phe Ser Gln Met Ser Glu Leu Leu Thr Arg Ala Glu Glu Arg Val Leu 
            260                 265                 270         


Val Arg Pro His Glu Pro Pro Pro Pro Pro Pro Met His Gly Ala Gly 
        275                 280                 285             


Asp Ala Lys Pro Ile Pro Thr Cys Ile Ser Ser Ala Thr Gly Leu Ile 
    290                 295                 300                 


Glu Asn Arg Pro Gln Ser Pro Ala Thr Gly Arg Thr Pro Val Phe Val 
305                 310                 315                 320 


Ser Pro Thr Pro Pro Pro Pro Pro Pro Pro Leu Pro Ser Ala Leu Ser 
                325                 330                 335     


Thr Ser Ser Leu Arg Ala Ser Met Thr Ser Thr Pro Pro Pro Pro Val 
            340                 345                 350         


Pro Pro Pro Pro Pro Pro Pro Ala Thr Ala Leu Gln Ala Pro Ala Val 
        355                 360                 365             


Pro Pro Pro Pro Ala Pro Leu Gln Ile Ala Pro Gly Val Leu His Pro 
    370                 375                 380                 


Ala Pro Pro Pro Ile Ala Pro Pro Leu Val Gln Pro Ser Pro Pro Val 
385                 390                 395                 400 


Ala Arg Ala Ala Pro Val Cys Glu Thr Val Pro Val His Pro Leu Pro 
                405                 410                 415     


Gln Gly Glu Val Gln Gly Leu Pro Pro Pro Pro Pro Pro Pro Pro Leu 
            420                 425                 430         


Pro Pro Pro Gly Ile Arg Pro Ser Ser Pro Val Thr Val Thr Ala Leu 
        435                 440                 445             


Ala His Pro Pro Ser Gly Leu His Pro Thr Pro Ser Thr Ala Pro Gly 
    450                 455                 460                 


Pro His Val Pro Leu Met Pro Pro Ser Pro Pro Ser Gln Val Ile Pro 
465                 470                 475                 480 


Ala Ser Glu Pro Lys Arg His Pro Ser Thr Leu Pro Val Ile Ser Asp 
                485                 490                 495     


Ala Arg Ser Val Leu Leu Glu Ala Ile Arg Lys Gly Ile Gln Leu Arg 
            500                 505                 510         


Lys Val Glu Glu Gln Arg Glu Gln Glu Ala Lys His Glu Arg Ile Glu 
        515                 520                 525             


Asn Asp Val Ala Thr Ile Leu Ser Arg Arg Ile Ala Val Glu Tyr Ser 
    530                 535                 540                 


Asp Ser Glu Asp Asp Ser Glu Phe Asp Glu Val Asp Trp Leu Glu 
545                 550                 555                 


<210>  4247
<211>  729
<212>  PRT
<213>  homo sapiens

<400>  4247

Met Ser Phe Gly Arg Asp Met Glu Leu Glu His Phe Asp Glu Arg Asp 
1               5                   10                  15      


Lys Ala Gln Arg Tyr Ser Arg Gly Ser Arg Val Asn Gly Leu Pro Ser 
            20                  25                  30          


Pro Thr His Ser Ala His Cys Ser Phe Tyr Arg Thr Arg Thr Leu Gln 
        35                  40                  45              


Thr Leu Ser Ser Glu Lys Lys Ala Lys Lys Val Arg Phe Tyr Arg Asn 
    50                  55                  60                  


Gly Asp Arg Tyr Phe Lys Gly Ile Val Tyr Ala Ile Ser Pro Asp Arg 
65                  70                  75                  80  


Phe Arg Ser Phe Glu Ala Leu Leu Ala Asp Leu Thr Arg Thr Leu Ser 
                85                  90                  95      


Asp Asn Val Asn Leu Pro Gln Gly Val Arg Thr Ile Tyr Thr Ile Asp 
            100                 105                 110         


Gly Leu Lys Lys Ile Ser Ser Leu Asp Gln Leu Val Glu Gly Glu Ser 
        115                 120                 125             


Tyr Val Cys Gly Ser Ile Glu Pro Phe Lys Lys Leu Glu Tyr Thr Lys 
    130                 135                 140                 


Asn Val Asn Pro Asn Trp Ser Val Asn Val Lys Thr Thr Ser Ala Ser 
145                 150                 155                 160 


Arg Ala Val Ser Ser Leu Ala Thr Ala Lys Gly Ser Pro Ser Glu Val 
                165                 170                 175     


Arg Glu Asn Lys Asp Phe Ile Arg Pro Lys Leu Val Thr Ile Ile Arg 
            180                 185                 190         


Ser Gly Val Lys Pro Arg Lys Ala Val Arg Ile Leu Leu Asn Lys Lys 
        195                 200                 205             


Thr Ala His Ser Phe Glu Gln Val Leu Thr Asp Ile Thr Asp Ala Ile 
    210                 215                 220                 


Lys Leu Asp Ser Gly Val Val Lys Arg Leu Tyr Thr Leu Asp Gly Lys 
225                 230                 235                 240 


Gln Val Met Cys Leu Gln Asp Phe Phe Gly Asp Asp Asp Ile Phe Ile 
                245                 250                 255     


Ala Cys Gly Pro Glu Lys Phe Arg Tyr Gln Asp Asp Phe Leu Leu Asp 
            260                 265                 270         


Glu Ser Glu Cys Arg Val Val Lys Ser Thr Ser Tyr Thr Lys Ile Ala 
        275                 280                 285             


Ser Ser Ser Arg Arg Ser Thr Thr Lys Ser Pro Gly Pro Ser Arg Arg 
    290                 295                 300                 


Ser Lys Ser Pro Ala Ser Thr Ser Ser Val Asn Gly Thr Pro Gly Ser 
305                 310                 315                 320 


Gln Leu Ser Thr Pro Arg Ser Gly Lys Ser Pro Ser Pro Ser Pro Thr 
                325                 330                 335     


Ser Pro Gly Ser Leu Arg Lys Gln Arg Ser Ser Gln His Gly Gly Ser 
            340                 345                 350         


Ser Thr Ser Leu Ala Ser Thr Lys Val Cys Ser Ser Met Asp Glu Asn 
        355                 360                 365             


Asp Gly Pro Gly Glu Glu Val Ser Glu Glu Gly Phe Gln Ile Pro Ala 
    370                 375                 380                 


Thr Ile Thr Glu Arg Tyr Lys Val Gly Arg Thr Ile Gly Asp Gly Asn 
385                 390                 395                 400 


Phe Ala Val Val Lys Glu Cys Val Glu Arg Ser Thr Ala Arg Glu Tyr 
                405                 410                 415     


Ala Leu Lys Ile Ile Lys Lys Ser Lys Cys Arg Gly Lys Glu His Met 
            420                 425                 430         


Ile Gln Asn Glu Val Ser Ile Leu Arg Arg Val Lys His Pro Asn Ile 
        435                 440                 445             


Val Leu Leu Ile Glu Glu Met Asp Val Pro Thr Glu Leu Tyr Leu Val 
    450                 455                 460                 


Met Glu Leu Val Lys Gly Gly Asp Leu Phe Asp Ala Ile Thr Ser Thr 
465                 470                 475                 480 


Asn Lys Tyr Thr Glu Arg Asp Ala Ser Gly Met Leu Tyr Asn Leu Ala 
                485                 490                 495     


Ser Ala Ile Lys Tyr Leu His Ser Leu Asn Ile Val His Arg Asp Ile 
            500                 505                 510         


Lys Pro Glu Asn Leu Leu Val Tyr Glu His Gln Asp Gly Ser Lys Ser 
        515                 520                 525             


Leu Lys Leu Gly Asp Phe Gly Leu Ala Thr Ile Val Asp Gly Pro Leu 
    530                 535                 540                 


Tyr Thr Val Cys Gly Thr Pro Thr Tyr Val Ala Pro Glu Ile Ile Ala 
545                 550                 555                 560 


Glu Thr Gly Tyr Gly Leu Lys Val Asp Ile Trp Ala Ala Gly Val Ile 
                565                 570                 575     


Thr Tyr Ile Leu Leu Cys Gly Phe Pro Pro Phe Arg Gly Ser Gly Asp 
            580                 585                 590         


Asp Gln Glu Val Leu Phe Asp Gln Ile Leu Met Gly Gln Val Asp Phe 
        595                 600                 605             


Pro Ser Pro Tyr Trp Asp Asn Val Ser Asp Ser Ala Lys Glu Leu Ile 
    610                 615                 620                 


Thr Met Met Leu Leu Val Asp Val Asp Gln Arg Phe Ser Ala Val Gln 
625                 630                 635                 640 


Val Leu Glu His Pro Trp Val Asn Asp Asp Gly Leu Pro Glu Asn Glu 
                645                 650                 655     


His Gln Leu Ser Val Ala Gly Lys Ile Lys Lys His Phe Asn Thr Gly 
            660                 665                 670         


Pro Lys Pro Asn Ser Thr Ala Ala Gly Val Ser Val Ile Ala Leu Asp 
        675                 680                 685             


His Gly Phe Thr Ile Lys Arg Ser Gly Ser Leu Asp Tyr Tyr Gln Gln 
    690                 695                 700                 


Pro Gly Met Tyr Trp Ile Arg Pro Pro Leu Leu Ile Arg Arg Gly Arg 
705                 710                 715                 720 


Phe Ser Asp Glu Asp Ala Thr Arg Met 
                725                 


<210>  4248
<211>  1794
<212>  PRT
<213>  homo sapiens

<400>  4248

Met Gly Asp Val Lys Leu Val Ala Ser Ser His Ile Ser Lys Thr Ser 
1               5                   10                  15      


Leu Ser Val Asp Pro Ser Arg Val Asp Ser Met Pro Leu Thr Glu Ala 
            20                  25                  30          


Pro Ala Phe Ile Leu Pro Pro Arg Asn Leu Cys Ile Lys Glu Gly Ala 
        35                  40                  45              


Thr Ala Lys Phe Glu Gly Arg Val Arg Gly Tyr Pro Glu Pro Gln Val 
    50                  55                  60                  


Thr Trp His Arg Asn Gly Gln Pro Ile Thr Ser Gly Gly Arg Phe Leu 
65                  70                  75                  80  


Leu Asp Cys Gly Ile Arg Gly Thr Phe Ser Leu Val Ile His Ala Val 
                85                  90                  95      


His Glu Glu Asp Arg Gly Lys Tyr Thr Cys Glu Ala Thr Asn Gly Ser 
            100                 105                 110         


Gly Ala Arg Gln Val Thr Val Glu Leu Thr Val Glu Gly Ser Phe Ala 
        115                 120                 125             


Lys Gln Leu Gly Gln Pro Val Val Ser Lys Thr Leu Gly Asp Arg Phe 
    130                 135                 140                 


Ser Ala Pro Ala Val Glu Thr Arg Pro Ser Ile Trp Gly Glu Cys Pro 
145                 150                 155                 160 


Pro Lys Phe Ala Thr Lys Leu Gly Arg Val Val Val Lys Glu Gly Gln 
                165                 170                 175     


Met Gly Arg Phe Ser Cys Lys Ile Thr Gly Arg Pro Gln Pro Gln Val 
            180                 185                 190         


Thr Trp Leu Lys Gly Asn Val Pro Leu Gln Pro Ser Ala Arg Val Ser 
        195                 200                 205             


Val Ser Glu Lys Asn Gly Met Gln Val Leu Glu Ile His Gly Val Asn 
    210                 215                 220                 


Gln Asp Asp Val Gly Val Tyr Thr Cys Leu Val Val Asn Gly Ser Gly 
225                 230                 235                 240 


Lys Ala Ser Met Ser Ala Glu Leu Ser Ile Gln Gly Leu Asp Ser Ala 
                245                 250                 255     


Asn Arg Ser Phe Val Arg Glu Thr Lys Ala Thr Asn Ser Asp Val Arg 
            260                 265                 270         


Lys Glu Val Thr Asn Val Ile Ser Lys Glu Ser Lys Leu Asp Ser Leu 
        275                 280                 285             


Glu Ala Ala Ala Lys Ser Lys Asn Cys Ser Ser Pro Gln Arg Gly Gly 
    290                 295                 300                 


Ser Pro Pro Trp Ala Ala Asn Ser Gln Pro Gln Pro Pro Arg Glu Ser 
305                 310                 315                 320 


Lys Leu Glu Ser Cys Lys Asp Ser Pro Arg Thr Ala Pro Gln Thr Pro 
                325                 330                 335     


Val Leu Gln Lys Thr Ser Ser Ser Ile Thr Leu Gln Ala Ala Arg Val 
            340                 345                 350         


Gln Pro Glu Pro Arg Ala Pro Gly Leu Gly Val Leu Ser Pro Ser Gly 
        355                 360                 365             


Glu Glu Arg Lys Arg Pro Ala Pro Pro Arg Pro Ala Thr Phe Pro Thr 
    370                 375                 380                 


Arg Gln Pro Gly Leu Gly Ser Gln Asp Val Val Ser Lys Ala Ala Asn 
385                 390                 395                 400 


Arg Arg Ile Pro Met Glu Gly Gln Arg Asp Ser Ala Phe Pro Lys Phe 
                405                 410                 415     


Glu Ser Lys Pro Gln Ser Gln Glu Val Lys Glu Asn Gln Thr Val Lys 
            420                 425                 430         


Phe Arg Cys Glu Gly Leu Ala Val Met Glu Val Ala Pro Ser Phe Ser 
        435                 440                 445             


Ser Val Leu Lys Asp Cys Ala Val Ile Glu Gly Gln Asp Phe Val Leu 
    450                 455                 460                 


Gln Cys Ser Val Arg Gly Thr Pro Val Pro Arg Ile Thr Trp Leu Leu 
465                 470                 475                 480 


Asn Gly Gln Pro Ile Gln Tyr Ala Arg Ser Thr Cys Glu Ala Gly Val 
                485                 490                 495     


Ala Glu Leu His Ile Gln Asp Ala Leu Pro Glu Asp His Gly Thr Tyr 
            500                 505                 510         


Thr Cys Leu Ala Glu Asn Ala Leu Gly Gln Val Ser Cys Ser Ala Trp 
        515                 520                 525             


Val Thr Val His Glu Lys Lys Ser Ser Arg Lys Ser Glu Tyr Leu Leu 
    530                 535                 540                 


Pro Val Ala Pro Ser Lys Pro Thr Ala Pro Ile Phe Leu Gln Gly Leu 
545                 550                 555                 560 


Ser Asp Leu Lys Val Met Asp Gly Ser Gln Val Thr Met Thr Val Gln 
                565                 570                 575     


Val Ser Gly Asn Pro Pro Pro Glu Val Ile Trp Leu His Asn Gly Asn 
            580                 585                 590         


Glu Ile Gln Glu Ser Glu Asp Phe His Phe Glu Gln Arg Gly Thr Gln 
        595                 600                 605             


His Ser Leu Cys Ile Gln Glu Val Phe Pro Glu Asp Thr Gly Thr Tyr 
    610                 615                 620                 


Thr Cys Glu Ala Trp Asn Ser Ala Gly Glu Val Arg Thr Gln Ala Val 
625                 630                 635                 640 


Leu Thr Val Gln Glu Pro His Asp Gly Thr Gln Pro Trp Phe Ile Ser 
                645                 650                 655     


Lys Pro Arg Ser Val Thr Ala Ser Leu Gly Gln Ser Val Leu Ile Ser 
            660                 665                 670         


Cys Ala Ile Ala Gly Asp Pro Phe Pro Thr Val His Trp Leu Arg Asp 
        675                 680                 685             


Gly Lys Ala Leu Cys Lys Asp Thr Gly His Phe Glu Val Leu Gln Asn 
    690                 695                 700                 


Glu Asp Val Phe Thr Leu Val Leu Lys Lys Val Gln Pro Trp His Ala 
705                 710                 715                 720 


Gly Gln Tyr Glu Ile Leu Leu Lys Asn Arg Val Gly Glu Cys Ser Cys 
                725                 730                 735     


Gln Val Ser Leu Met Leu Gln Asn Ser Ser Ala Arg Ala Leu Pro Arg 
            740                 745                 750         


Gly Arg Glu Pro Ala Ser Cys Glu Asp Leu Cys Gly Gly Gly Val Gly 
        755                 760                 765             


Ala Asp Gly Gly Gly Ser Asp Arg Tyr Gly Ser Leu Arg Pro Gly Trp 
    770                 775                 780                 


Pro Ala Arg Gly Gln Gly Trp Leu Glu Glu Glu Asp Gly Glu Asp Val 
785                 790                 795                 800 


Arg Gly Val Leu Lys Arg Arg Val Glu Thr Arg Gln His Thr Glu Glu 
                805                 810                 815     


Ala Ile Arg Gln Gln Glu Val Glu Gln Leu Asp Phe Arg Asp Leu Leu 
            820                 825                 830         


Gly Lys Lys Val Ser Thr Lys Thr Leu Ser Glu Asp Asp Leu Lys Glu 
        835                 840                 845             


Ile Pro Ala Glu Gln Met Asp Phe Arg Ala Asn Leu Gln Arg Gln Val 
    850                 855                 860                 


Lys Pro Lys Thr Val Ser Glu Glu Glu Arg Lys Val His Ser Pro Gln 
865                 870                 875                 880 


Gln Val Asp Phe Arg Ser Val Leu Ala Lys Lys Gly Thr Ser Lys Thr 
                885                 890                 895     


Pro Val Pro Glu Lys Val Pro Pro Pro Lys Pro Ala Thr Pro Asp Phe 
            900                 905                 910         


Arg Ser Val Leu Gly Gly Lys Lys Lys Leu Pro Ala Glu Asn Gly Ser 
        915                 920                 925             


Ser Ser Ala Glu Thr Leu Asn Ala Lys Ala Val Glu Ser Ser Lys Pro 
    930                 935                 940                 


Leu Ser Asn Ala Gln Pro Ser Gly Pro Leu Lys Pro Val Gly Asn Ala 
945                 950                 955                 960 


Lys Pro Ala Glu Thr Leu Lys Pro Met Gly Asn Ala Lys Pro Ala Glu 
                965                 970                 975     


Thr Leu Lys Pro Met Gly Asn Ala Lys Pro Asp Glu Asn Leu Lys Ser 
            980                 985                 990         


Ala Ser Lys Glu Glu Leu Lys Lys  Asp Val Lys Asn Asp  Val Asn Cys 
        995                 1000                 1005             


Lys Arg  Gly His Ala Gly Thr  Thr Asp Asn Glu Lys  Arg Ser Glu 
    1010                 1015                 1020             


Ser Gln  Gly Thr Ala Pro Ala  Phe Lys Gln Lys Leu  Gln Asp Val 
    1025                 1030                 1035             


His Val  Ala Glu Gly Lys Lys  Leu Leu Leu Gln Cys  Gln Val Ser 
    1040                 1045                 1050             


Ser Asp  Pro Pro Ala Thr Ile  Ile Trp Thr Leu Asn  Gly Lys Thr 
    1055                 1060                 1065             


Leu Lys  Thr Thr Lys Phe Ile  Ile Leu Ser Gln Glu  Gly Ser Leu 
    1070                 1075                 1080             


Cys Ser  Val Ser Ile Glu Lys  Ala Leu Pro Glu Asp  Arg Gly Leu 
    1085                 1090                 1095             


Tyr Lys  Cys Val Ala Lys Asn  Asp Ala Gly Gln Ala  Glu Cys Ser 
    1100                 1105                 1110             


Cys Gln  Val Thr Val Asp Asp  Ala Pro Ala Ser Glu  Asn Thr Lys 
    1115                 1120                 1125             


Ala Pro  Glu Met Lys Ser Arg  Arg Pro Lys Ser Ser  Leu Pro Pro 
    1130                 1135                 1140             


Val Leu  Gly Thr Glu Ser Asp  Ala Thr Val Lys Lys  Lys Pro Ala 
    1145                 1150                 1155             


Pro Lys  Thr Pro Pro Lys Ala  Ala Met Pro Pro Gln  Ile Ile Gln 
    1160                 1165                 1170             


Phe Pro  Glu Asp Gln Lys Val  Arg Ala Gly Glu Ser  Val Glu Leu 
    1175                 1180                 1185             


Phe Gly  Lys Val Thr Gly Thr  Gln Pro Ile Thr Cys  Thr Trp Met 
    1190                 1195                 1200             


Lys Phe  Arg Lys Gln Ile Gln  Glu Ser Glu His Met  Lys Val Glu 
    1205                 1210                 1215             


Asn Ser  Glu Asn Gly Ser Lys  Leu Thr Ile Leu Ala  Ala Arg Gln 
    1220                 1225                 1230             


Glu His  Cys Gly Cys Tyr Thr  Leu Leu Val Glu Asn  Lys Leu Gly 
    1235                 1240                 1245             


Ser Arg  Gln Ala Gln Val Asn  Leu Thr Val Val Asp  Lys Pro Asp 
    1250                 1255                 1260             


Pro Pro  Ala Gly Thr Pro Cys  Ala Ser Asp Ile Arg  Ser Ser Ser 
    1265                 1270                 1275             


Leu Thr  Leu Ser Trp Tyr Gly  Ser Ser Tyr Asp Gly  Gly Ser Ala 
    1280                 1285                 1290             


Val Gln  Ser Tyr Ser Ile Glu  Ile Trp Asp Ser Ala  Asn Lys Thr 
    1295                 1300                 1305             


Trp Lys  Glu Leu Ala Thr Cys  Arg Ser Thr Ser Phe  Asn Val Gln 
    1310                 1315                 1320             


Asp Leu  Leu Pro Asp His Glu  Tyr Lys Phe Arg Val  Arg Ala Ile 
    1325                 1330                 1335             


Asn Val  Tyr Gly Thr Ser Glu  Pro Ser Gln Glu Ser  Glu Leu Thr 
    1340                 1345                 1350             


Thr Val  Gly Glu Lys Pro Glu  Glu Pro Lys Asp Glu  Val Glu Val 
    1355                 1360                 1365             


Ser Asp  Asp Asp Glu Lys Glu  Pro Glu Val Asp Tyr  Arg Thr Val 
    1370                 1375                 1380             


Thr Ile  Asn Thr Glu Gln Lys  Val Ser Asp Phe Tyr  Asp Ile Glu 
    1385                 1390                 1395             


Glu Arg  Leu Gly Ser Gly Lys  Phe Gly Gln Val Phe  Arg Leu Val 
    1400                 1405                 1410             


Glu Lys  Lys Thr Arg Lys Val  Trp Ala Gly Lys Phe  Phe Lys Ala 
    1415                 1420                 1425             


Tyr Ser  Ala Lys Glu Lys Glu  Asn Ile Arg Gln Glu  Ile Ser Ile 
    1430                 1435                 1440             


Met Asn  Cys Leu His His Pro  Lys Leu Val Gln Cys  Val Asp Ala 
    1445                 1450                 1455             


Phe Glu  Glu Lys Ala Asn Ile  Val Met Val Leu Glu  Ile Val Ser 
    1460                 1465                 1470             


Gly Gly  Glu Leu Phe Glu Arg  Ile Ile Asp Glu Asp  Phe Glu Leu 
    1475                 1480                 1485             


Thr Glu  Arg Glu Cys Ile Lys  Tyr Met Arg Gln Ile  Ser Glu Gly 
    1490                 1495                 1500             


Val Glu  Tyr Ile His Lys Gln  Gly Ile Val His Leu  Asp Leu Lys 
    1505                 1510                 1515             


Pro Glu  Asn Ile Met Cys Val  Asn Lys Thr Gly Thr  Arg Ile Lys 
    1520                 1525                 1530             


Leu Ile  Asp Phe Gly Leu Ala  Arg Arg Leu Glu Asn  Ala Gly Ser 
    1535                 1540                 1545             


Leu Lys  Val Leu Phe Gly Thr  Pro Glu Phe Val Ala  Pro Glu Val 
    1550                 1555                 1560             


Ile Asn  Tyr Glu Pro Ile Gly  Tyr Ala Thr Asp Met  Trp Ser Ile 
    1565                 1570                 1575             


Gly Val  Ile Cys Tyr Ile Leu  Asn Arg Leu Asp Cys  Thr Gln Cys 
    1580                 1585                 1590             


Leu Gln  His Pro Trp Leu Met  Lys Asp Thr Lys Asn  Met Glu Ala 
    1595                 1600                 1605             


Lys Lys  Leu Ser Lys Asp Arg  Met Lys Lys Tyr Met  Ala Arg Arg 
    1610                 1615                 1620             


Lys Trp  Gln Lys Thr Gly Asn  Ala Val Arg Ala Ile  Gly Arg Leu 
    1625                 1630                 1635             


Ser Ser  Met Ala Met Ile Ser  Gly Leu Ser Gly Arg  Lys Ser Ser 
    1640                 1645                 1650             


Thr Gly  Ser Pro Thr Ser Pro  Leu Asn Ala Glu Lys  Leu Glu Ser 
    1655                 1660                 1665             


Glu Glu  Asp Val Ser Gln Ala  Phe Leu Glu Ala Val  Ala Glu Glu 
    1670                 1675                 1680             


Lys Pro  His Val Lys Pro Tyr  Phe Ser Lys Thr Ile  Arg Asp Leu 
    1685                 1690                 1695             


Glu Val  Val Glu Gly Ser Ala  Ala Arg Phe Asp Cys  Lys Ile Glu 
    1700                 1705                 1710             


Gly Tyr  Pro Asp Pro Glu Val  Val Trp Phe Lys Asp  Asp Gln Ser 
    1715                 1720                 1725             


Ile Arg  Glu Ser Arg His Phe  Gln Ile Asp Tyr Asp  Glu Asp Gly 
    1730                 1735                 1740             


Asn Cys  Ser Leu Ile Ile Ser  Asp Val Cys Gly Asp  Asp Asp Ala 
    1745                 1750                 1755             


Lys Tyr  Thr Cys Lys Ala Val  Asn Ser Leu Gly Glu  Ala Thr Cys 
    1760                 1765                 1770             


Thr Ala  Glu Leu Ile Val Glu  Thr Met Glu Glu Gly  Glu Gly Glu 
    1775                 1780                 1785             


Gly Glu  Glu Glu Glu Glu 
    1790                 


<210>  4249
<211>  296
<212>  PRT
<213>  homo sapiens

<400>  4249

Met Glu His Leu Lys Ala Phe Asp Asp Glu Ile Asn Ala Phe Leu Asp 
1               5                   10                  15      


Asn Met Phe Gly Pro Arg Asp Ser Arg Val Arg Gly Trp Phe Met Leu 
            20                  25                  30          


Asp Ser Tyr Leu Pro Thr Phe Phe Leu Thr Val Met Tyr Leu Leu Ser 
        35                  40                  45              


Ile Trp Leu Gly Asn Lys Tyr Met Lys Asn Arg Pro Ala Leu Ser Leu 
    50                  55                  60                  


Arg Gly Ile Leu Thr Leu Tyr Asn Leu Gly Ile Thr Leu Leu Ser Ala 
65                  70                  75                  80  


Tyr Met Leu Ala Glu Leu Ile Leu Ser Thr Trp Glu Gly Gly Tyr Asn 
                85                  90                  95      


Leu Gln Cys Gln Asp Leu Thr Ser Ala Gly Glu Ala Asp Ile Arg Val 
            100                 105                 110         


Ala Lys Val Leu Trp Trp Tyr Tyr Phe Ser Lys Ser Val Glu Phe Leu 
        115                 120                 125             


Asp Thr Ile Phe Phe Val Leu Arg Lys Lys Thr Ser Gln Ile Thr Phe 
    130                 135                 140                 


Leu His Val Tyr His His Ala Ser Met Phe Asn Ile Trp Trp Cys Val 
145                 150                 155                 160 


Leu Asn Trp Ile Pro Cys Gly Gln Ser Phe Phe Gly Pro Thr Leu Asn 
                165                 170                 175     


Ser Phe Ile His Ile Leu Met Tyr Ser Tyr Tyr Gly Leu Ser Val Phe 
            180                 185                 190         


Pro Ser Met His Lys Tyr Leu Trp Trp Lys Lys Tyr Leu Thr Gln Ala 
        195                 200                 205             


Gln Leu Val Gln Phe Val Leu Thr Ile Thr His Thr Met Ser Ala Val 
    210                 215                 220                 


Val Lys Pro Cys Gly Phe Pro Phe Gly Cys Leu Ile Phe Gln Ser Ser 
225                 230                 235                 240 


Tyr Met Leu Thr Leu Val Ile Leu Phe Leu Asn Phe Tyr Val Gln Thr 
                245                 250                 255     


Tyr Arg Lys Lys Pro Met Lys Lys Asp Met Gln Glu Pro Pro Ala Gly 
            260                 265                 270         


Lys Glu Val Lys Asn Gly Phe Ser Lys Ala Tyr Phe Thr Ala Ala Asn 
        275                 280                 285             


Gly Val Met Asn Lys Lys Ala Gln 
    290                 295     


<210>  4250
<211>  522
<212>  PRT
<213>  homo sapiens

<400>  4250

Met Glu Phe Pro Asp His Ser Arg His Leu Leu Gln Cys Leu Ser Glu 
1               5                   10                  15      


Gln Arg His Gln Gly Phe Leu Cys Asp Cys Thr Val Leu Val Gly Asp 
            20                  25                  30          


Ala Gln Phe Arg Ala His Arg Ala Val Leu Ala Ser Cys Ser Met Tyr 
        35                  40                  45              


Phe His Leu Phe Tyr Lys Asp Gln Leu Asp Lys Arg Asp Ile Val His 
    50                  55                  60                  


Leu Asn Ser Asp Ile Val Thr Ala Pro Ala Phe Ala Leu Leu Leu Glu 
65                  70                  75                  80  


Phe Met Tyr Glu Gly Lys Leu Gln Phe Lys Asp Leu Pro Ile Glu Asp 
                85                  90                  95      


Val Leu Ala Ala Ala Ser Tyr Leu His Met Tyr Asp Ile Val Lys Val 
            100                 105                 110         


Cys Lys Lys Lys Leu Lys Glu Lys Ala Thr Thr Glu Ala Asp Ser Thr 
        115                 120                 125             


Lys Lys Glu Glu Asp Ala Ser Ser Cys Ser Asp Lys Val Glu Ser Leu 
    130                 135                 140                 


Ser Asp Gly Ser Ser His Ile Ala Gly Asp Leu Pro Ser Asp Glu Asp 
145                 150                 155                 160 


Glu Gly Glu Asp Glu Lys Leu Asn Ile Leu Pro Ser Lys Arg Asp Leu 
                165                 170                 175     


Ala Ala Glu Pro Gly Asn Met Trp Met Arg Leu Pro Ser Asp Ser Ala 
            180                 185                 190         


Gly Ile Pro Gln Ala Gly Gly Glu Ala Glu Pro His Ala Thr Ala Ala 
        195                 200                 205             


Gly Lys Thr Val Ala Ser Pro Cys Ser Ser Thr Glu Ser Leu Ser Gln 
    210                 215                 220                 


Arg Ser Val Thr Ser Val Arg Asp Ser Ala Asp Val Asp Cys Val Leu 
225                 230                 235                 240 


Asp Leu Ser Val Lys Ser Ser Leu Ser Gly Val Glu Asn Leu Asn Ser 
                245                 250                 255     


Ser Tyr Phe Ser Ser Gln Asp Val Leu Arg Ser Asn Leu Val Gln Val 
            260                 265                 270         


Lys Val Glu Lys Glu Ala Ser Cys Asp Glu Ser Asp Val Gly Thr Asn 
        275                 280                 285             


Asp Tyr Asp Met Glu His Ser Thr Val Lys Glu Ser Val Ser Thr Asn 
    290                 295                 300                 


Asn Arg Val Gln Tyr Glu Pro Ala His Leu Ala Pro Leu Arg Glu Asp 
305                 310                 315                 320 


Ser Val Leu Arg Glu Leu Asp Arg Glu Asp Lys Ala Ser Asp Asp Glu 
                325                 330                 335     


Met Met Thr Pro Glu Ser Glu Arg Val Gln Val Glu Gly Gly Met Glu 
            340                 345                 350         


Ser Ser Leu Leu Pro Tyr Val Ser Asn Ile Leu Ser Pro Ala Gly Gln 
        355                 360                 365             


Ile Phe Met Cys Pro Leu Cys Asn Lys Val Phe Pro Ser Pro His Ile 
    370                 375                 380                 


Leu Gln Ile His Leu Ser Thr His Phe Arg Glu Gln Asp Gly Ile Arg 
385                 390                 395                 400 


Ser Lys Pro Ala Ala Asp Val Asn Val Pro Thr Cys Ser Leu Cys Gly 
                405                 410                 415     


Lys Thr Phe Ser Cys Met Tyr Thr Leu Lys Arg His Glu Arg Thr His 
            420                 425                 430         


Ser Gly Glu Lys Pro Tyr Thr Cys Thr Gln Cys Gly Lys Ser Phe Gln 
        435                 440                 445             


Tyr Ser His Asn Leu Ser Arg His Ala Val Val His Thr Arg Glu Lys 
    450                 455                 460                 


Pro His Ala Cys Lys Trp Cys Glu Arg Arg Phe Thr Gln Ser Gly Asp 
465                 470                 475                 480 


Leu Tyr Arg His Ile Arg Lys Phe His Cys Glu Leu Val Asn Ser Leu 
                485                 490                 495     


Ser Val Lys Ser Glu Ala Leu Ser Leu Pro Thr Val Arg Asp Trp Thr 
            500                 505                 510         


Leu Glu Asp Ser Ser Gln Glu Leu Trp Lys 
        515                 520         


<210>  4251
<211>  216
<212>  PRT
<213>  homo sapiens

<400>  4251

Met Gly Pro Arg Asn Pro Ser Pro Asp His Leu Ser Glu Ser Glu Ser 
1               5                   10                  15      


Glu Glu Glu Glu Asn Ile Ser Tyr Leu Asn Glu Ser Ser Gly Glu Glu 
            20                  25                  30          


Trp Asp Ser Ser Glu Glu Glu Asp Ser Met Val Pro Asn Leu Ser Pro 
        35                  40                  45              


Leu Glu Ser Leu Ala Trp Gln Val Lys Cys Leu Leu Lys Tyr Ser Thr 
    50                  55                  60                  


Thr Trp Lys Pro Leu Asn Pro Asn Ser Trp Leu Tyr His Ala Lys Leu 
65                  70                  75                  80  


Leu Asp Pro Ser Thr Pro Val His Ile Leu Arg Glu Ile Gly Leu Arg 
                85                  90                  95      


Leu Ser His Cys Ser His Cys Val Pro Lys Leu Glu Pro Ile Pro Glu 
            100                 105                 110         


Trp Pro Pro Leu Ala Ser Cys Gly Val Pro Pro Phe Gln Lys Pro Leu 
        115                 120                 125             


Thr Ser Pro Ser Arg Leu Ser Arg Asp His Ala Thr Leu Asn Gly Ala 
    130                 135                 140                 


Leu Gln Phe Ala Thr Lys Gln Leu Ser Arg Thr Leu Ser Arg Ala Thr 
145                 150                 155                 160 


Pro Ile Pro Glu Tyr Leu Lys Gln Ile Pro Asn Ser Cys Val Ser Gly 
                165                 170                 175     


Cys Cys Cys Gly Trp Leu Thr Lys Thr Val Lys Glu Thr Thr Arg Thr 
            180                 185                 190         


Glu Pro Ile Asn Thr Thr Tyr Ser Tyr Thr Asp Phe Gln Lys Ala Val 
        195                 200                 205             


Asn Lys Leu Leu Thr Ala Ser Leu 
    210                 215     


<210>  4252
<211>  1584
<212>  PRT
<213>  homo sapiens

<400>  4252

Met Ser Leu Thr Ser Trp Phe Leu Val Ser Ser Gly Gly Thr Arg His 
1               5                   10                  15      


Arg Leu Pro Arg Glu Met Ile Phe Val Gly Arg Asp Asp Cys Glu Leu 
            20                  25                  30          


Met Leu Gln Ser Arg Ser Val Asp Lys Gln His Ala Val Ile Asn Tyr 
        35                  40                  45              


Asp Ala Ser Thr Asp Glu His Leu Val Lys Asp Leu Gly Ser Leu Asn 
    50                  55                  60                  


Gly Thr Phe Val Asn Asp Val Arg Ile Pro Glu Gln Thr Tyr Ile Thr 
65                  70                  75                  80  


Leu Lys Leu Glu Asp Lys Leu Arg Phe Gly Tyr Asp Thr Asn Leu Phe 
                85                  90                  95      


Thr Val Val Gln Gly Glu Met Arg Val Pro Glu Glu Ala Leu Lys His 
            100                 105                 110         


Glu Lys Phe Thr Ile Gln Leu Gln Leu Ser Gln Lys Ser Ser Glu Ser 
        115                 120                 125             


Glu Leu Ser Lys Ser Ala Ser Ala Lys Ser Ile Asp Ser Lys Val Ala 
    130                 135                 140                 


Asp Ala Ala Thr Glu Val Gln His Lys Thr Thr Glu Ala Leu Lys Ser 
145                 150                 155                 160 


Glu Glu Lys Ala Met Asp Ile Ser Ala Met Pro Arg Gly Thr Pro Leu 
                165                 170                 175     


Tyr Gly Gln Pro Ser Trp Trp Gly Asp Asp Glu Val Asp Glu Lys Arg 
            180                 185                 190         


Ala Phe Lys Thr Asn Gly Lys Pro Glu Glu Lys Asn His Glu Ala Gly 
        195                 200                 205             


Thr Ser Gly Cys Gly Ile Asp Ala Lys Gln Val Glu Glu Gln Ser Ala 
    210                 215                 220                 


Ala Ala Asn Glu Glu Val Leu Phe Pro Phe Cys Arg Glu Pro Ser Tyr 
225                 230                 235                 240 


Phe Glu Ile Pro Thr Lys Glu Phe Gln Gln Pro Ser Gln Ile Thr Glu 
                245                 250                 255     


Ser Thr Ile His Glu Ile Pro Thr Lys Asp Thr Pro Ser Ser His Ile 
            260                 265                 270         


Thr Gly Ala Gly His Ala Ser Phe Thr Ile Glu Phe Asp Asp Ser Thr 
        275                 280                 285             


Pro Gly Lys Val Thr Ile Arg Asp His Val Thr Lys Phe Thr Ser Asp 
    290                 295                 300                 


Gln Arg His Lys Ser Lys Lys Ser Ser Pro Gly Thr Gln Asp Leu Leu 
305                 310                 315                 320 


Gly Ile Gln Thr Gly Met Met Ala Pro Glu Asn Lys Val Ala Asp Trp 
                325                 330                 335     


Leu Ala Gln Asn Asn Pro Pro Gln Met Leu Trp Glu Arg Thr Glu Glu 
            340                 345                 350         


Asp Ser Lys Ser Ile Lys Ser Asp Val Pro Val Tyr Leu Lys Arg Leu 
        355                 360                 365             


Lys Gly Asn Lys His Asp Asp Gly Thr Gln Ser Asp Ser Glu Asn Ala 
    370                 375                 380                 


Gly Ala His Arg Arg Cys Ser Lys Arg Ala Thr Leu Glu Glu His Leu 
385                 390                 395                 400 


Arg Arg His His Ser Glu His Lys Lys Leu Gln Lys Val Gln Ala Thr 
                405                 410                 415     


Glu Lys His Gln Asp Gln Ala Val Thr Ser Ser Ala His His Arg Gly 
            420                 425                 430         


Gly His Gly Val Pro His Gly Lys Leu Leu Lys Gln Lys Ser Glu Glu 
        435                 440                 445             


Pro Ser Val Ser Ile Pro Phe Leu Gln Thr Ala Leu Leu Arg Ser Ser 
    450                 455                 460                 


Gly Ser Leu Gly His Arg Pro Ser Gln Glu Met Asp Lys Met Leu Lys 
465                 470                 475                 480 


Asn Gln Ala Thr Ser Ala Thr Ser Glu Lys Asp Asn Asp Asp Asp Gln 
                485                 490                 495     


Ser Asp Lys Gly Thr Tyr Thr Ile Glu Leu Glu Asn Pro Asn Ser Glu 
            500                 505                 510         


Glu Val Glu Ala Arg Lys Met Ile Asp Lys Val Phe Gly Val Asp Asp 
        515                 520                 525             


Asn Gln Asp Tyr Asn Arg Pro Val Ile Asn Glu Lys His Lys Asp Leu 
    530                 535                 540                 


Ile Lys Asp Trp Ala Leu Ser Ser Ala Ala Ala Val Met Glu Glu Arg 
545                 550                 555                 560 


Lys Pro Leu Thr Thr Ser Gly Phe His His Ser Glu Glu Gly Thr Ser 
                565                 570                 575     


Ser Ser Gly Ser Lys Arg Trp Val Ser Gln Trp Ala Ser Leu Ala Ala 
            580                 585                 590         


Asn His Thr Arg His Asp Gln Glu Glu Arg Ile Met Glu Phe Ser Ala 
        595                 600                 605             


Pro Leu Pro Leu Glu Asn Glu Thr Glu Ile Ser Glu Ser Gly Met Thr 
    610                 615                 620                 


Val Arg Ser Thr Gly Ser Ala Thr Ser Leu Ala Ser Gln Gly Glu Arg 
625                 630                 635                 640 


Arg Arg Arg Thr Leu Pro Gln Leu Pro Asn Glu Glu Lys Ser Leu Glu 
                645                 650                 655     


Ser His Arg Ala Lys Val Val Thr Gln Arg Ser Glu Ile Gly Glu Lys 
            660                 665                 670         


Gln Asp Thr Glu Leu Gln Glu Lys Glu Thr Pro Thr Gln Val Tyr Gln 
        675                 680                 685             


Lys Asp Lys Gln Asp Ala Asp Arg Pro Leu Ser Lys Met Asn Arg Ala 
    690                 695                 700                 


Val Asn Gly Glu Thr Leu Lys Thr Gly Gly Asp Asn Lys Thr Leu Leu 
705                 710                 715                 720 


His Leu Gly Ser Ser Ala Pro Gly Lys Glu Lys Ser Glu Thr Asp Lys 
                725                 730                 735     


Glu Thr Ser Leu Val Lys Gln Thr Leu Ala Lys Leu Gln Gln Gln Glu 
            740                 745                 750         


Gln Arg Glu Glu Ala Gln Trp Thr Pro Thr Lys Leu Ser Ser Lys Asn 
        755                 760                 765             


Val Ser Gly Gln Thr Asp Lys Cys Arg Glu Glu Thr Phe Lys Gln Glu 
    770                 775                 780                 


Ser Gln Pro Pro Glu Lys Asn Ser Gly His Ser Thr Ser Lys Gly Asp 
785                 790                 795                 800 


Arg Val Ala Gln Ser Glu Ser Lys Arg Arg Lys Ala Glu Glu Ile Leu 
                805                 810                 815     


Lys Ser Gln Thr Pro Lys Gly Gly Asp Lys Lys Glu Ser Ser Lys Ser 
            820                 825                 830         


Leu Val Arg Gln Gly Ser Phe Thr Ile Glu Lys Pro Ser Pro Asn Ile 
        835                 840                 845             


Pro Ile Glu Leu Ile Pro His Ile Asn Lys Gln Thr Ser Ser Thr Pro 
    850                 855                 860                 


Ser Ser Leu Ala Leu Thr Ser Ala Ser Arg Ile Arg Glu Arg Ser Glu 
865                 870                 875                 880 


Ser Leu Asp Pro Asp Ser Ser Met Asp Thr Thr Leu Ile Leu Lys Asp 
                885                 890                 895     


Thr Glu Ala Val Met Ala Phe Leu Glu Ala Lys Leu Arg Glu Asp Asn 
            900                 905                 910         


Lys Thr Asp Glu Gly Pro Asp Thr Pro Ser Tyr Asn Arg Asp Asn Ser 
        915                 920                 925             


Ile Ser Pro Glu Ser Asp Val Asp Thr Ala Ser Thr Ile Ser Leu Val 
    930                 935                 940                 


Thr Gly Glu Thr Glu Arg Lys Ser Thr Gln Lys Arg Lys Ser Phe Thr 
945                 950                 955                 960 


Ser Leu Tyr Lys Asp Arg Cys Ser Thr Gly Ser Pro Ser Lys Asp Val 
                965                 970                 975     


Thr Lys Ser Ser Ser Ser Gly Ala Arg Glu Lys Met Glu Lys Lys Thr 
            980                 985                 990         


Lys Ser Arg Ser Thr Asp Val Gly  Ser Arg Ala Asp Gly  Arg Lys Phe 
        995                 1000                 1005             


Val Gln  Ser Ser Gly Arg Ile  Arg Gln Pro Ser Val  Asp Leu Thr 
    1010                 1015                 1020             


Asp Asp  Asp Gln Thr Ser Ser  Val Pro His Ser Ala  Ile Ser Asp 
    1025                 1030                 1035             


Ile Met  Ser Ser Asp Gln Glu  Thr Tyr Ser Cys Lys  Pro His Gly 
    1040                 1045                 1050             


Arg Thr  Pro Leu Thr Ser Ala  Asp Glu His Val His  Ser Lys Leu 
    1055                 1060                 1065             


Glu Gly  Ser Lys Val Thr Lys  Ser Lys Thr Ser Pro  Val Val Ser 
    1070                 1075                 1080             


Gly Ser  Ser Ser Lys Ser Thr  Thr Leu Pro Arg Pro  Arg Pro Thr 
    1085                 1090                 1095             


Arg Thr  Ser Leu Leu Arg Arg  Ala Arg Leu Gly Glu  Ala Ser Asp 
    1100                 1105                 1110             


Ser Glu  Leu Ala Asp Ala Asp  Lys Ala Ser Val Ala  Ser Glu Val 
    1115                 1120                 1125             


Ser Thr  Thr Ser Ser Thr Ser  Lys Pro Pro Thr Gly  Arg Arg Asn 
    1130                 1135                 1140             


Ile Ser  Arg Ile Asp Leu Leu  Ala Gln Pro Arg Arg  Thr Arg Leu 
    1145                 1150                 1155             


Gly Ser  Leu Ser Ala Arg Ser  Asp Ser Glu Ala Thr  Ile Ser Arg 
    1160                 1165                 1170             


Ser Ser  Ala Ser Ser Arg Thr  Ala Glu Ala Ile Ile  Arg Ser Gly 
    1175                 1180                 1185             


Ala Arg  Leu Val Pro Ser Asp  Lys Phe Ser Pro Arg  Ile Arg Ala 
    1190                 1195                 1200             


Asn Ser  Ile Ser Arg Leu Ser  Asp Ser Lys Val Lys  Ser Met Thr 
    1205                 1210                 1215             


Ser Ala  His Gly Ser Ala Ser  Val Asn Ser Arg Trp  Arg Arg Phe 
    1220                 1225                 1230             


Pro Thr  Asp Tyr Ala Ser Thr  Ser Glu Asp Glu Phe  Gly Ser Asn 
    1235                 1240                 1245             


Arg Asn  Ser Pro Lys His Thr  Arg Leu Arg Thr Ser  Pro Ala Leu 
    1250                 1255                 1260             


Lys Thr  Thr Arg Leu Gln Ser  Ala Gly Ser Ala Met  Pro Thr Ser 
    1265                 1270                 1275             


Ser Ser  Phe Lys His Arg Ile  Lys Glu Gln Glu Asp  Tyr Ile Arg 
    1280                 1285                 1290             


Asp Trp  Thr Ala His Arg Glu  Glu Ile Ala Arg Ile  Ser Gln Asp 
    1295                 1300                 1305             


Leu Ala  Leu Ile Ala Arg Glu  Ile Asn Asp Val Ala  Gly Glu Ile 
    1310                 1315                 1320             


Asp Ser  Val Thr Ser Ser Gly  Thr Ala Pro Ser Thr  Thr Val Ser 
    1325                 1330                 1335             


Thr Ala  Ala Thr Thr Pro Gly  Ser Ala Ile Asp Thr  Arg Glu Glu 
    1340                 1345                 1350             


Leu Val  Asp Arg Val Phe Asp  Glu Ser Leu Asn Phe  Arg Lys Ile 
    1355                 1360                 1365             


Pro Pro  Leu Val His Ser Lys  Thr Pro Glu Gly Asn  Asn Gly Arg 
    1370                 1375                 1380             


Ser Gly  Asp Pro Arg Pro Gln  Ala Ala Glu Pro Pro  Asp His Leu 
    1385                 1390                 1395             


Thr Ile  Thr Arg Arg Arg Thr  Trp Ser Arg Asp Glu  Val Met Gly 
    1400                 1405                 1410             


Asp Asn  Leu Leu Leu Ser Ser  Val Phe Gln Phe Ser  Lys Lys Ile 
    1415                 1420                 1425             


Arg Gln  Ser Ile Asp Lys Thr  Ala Gly Lys Ile Arg  Ile Leu Phe 
    1430                 1435                 1440             


Lys Asp  Lys Asp Arg Asn Trp  Asp Asp Ile Glu Ser  Lys Leu Arg 
    1445                 1450                 1455             


Ala Glu  Ser Glu Val Pro Ile  Val Lys Thr Ser Ser  Met Glu Ile 
    1460                 1465                 1470             


Ser Ser  Ile Leu Gln Glu Leu  Lys Arg Val Glu Lys  Gln Leu Gln 
    1475                 1480                 1485             


Ala Ile  Asn Ala Met Ile Asp  Pro Asp Gly Thr Leu  Glu Ala Leu 
    1490                 1495                 1500             


Asn Asn  Met Gly Phe Pro Ser  Ala Met Leu Pro Ser  Pro Pro Lys 
    1505                 1510                 1515             


Gln Lys  Ser Ser Pro Val Asn  Asn His His Ser Pro  Gly Gln Thr 
    1520                 1525                 1530             


Pro Thr  Leu Gly Gln Pro Glu  Ala Arg Ala Leu His  Pro Ala Ala 
    1535                 1540                 1545             


Val Ser  Ala Ala Ala Glu Phe  Glu Asn Ala Glu Ser  Glu Ala Asp 
    1550                 1555                 1560             


Phe Ser  Ile His Phe Asn Arg  Phe Asn Pro Asp Gly  Glu Glu Glu 
    1565                 1570                 1575             


Asp Val  Thr Val Gln Glu 
    1580                 


<210>  4253
<211>  816
<212>  PRT
<213>  homo sapiens

<400>  4253

Met Glu Ser Arg Val Leu Leu Arg Thr Phe Cys Leu Ile Phe Gly Leu 
1               5                   10                  15      


Gly Ala Val Trp Gly Leu Gly Val Asp Pro Ser Leu Gln Ile Asp Val 
            20                  25                  30          


Leu Thr Glu Leu Glu Leu Gly Glu Ser Thr Thr Gly Val Arg Gln Val 
        35                  40                  45              


Pro Gly Leu His Asn Gly Thr Lys Ala Phe Leu Phe Gln Asp Thr Pro 
    50                  55                  60                  


Arg Ser Ile Lys Ala Ser Thr Ala Thr Ala Glu Gln Phe Phe Gln Lys 
65                  70                  75                  80  


Leu Arg Asn Lys His Glu Phe Thr Ile Leu Val Thr Leu Lys Gln Thr 
                85                  90                  95      


His Leu Asn Ser Gly Val Ile Leu Ser Ile His His Leu Asp His Arg 
            100                 105                 110         


Tyr Leu Glu Leu Glu Ser Ser Gly His Arg Asn Glu Val Arg Leu His 
        115                 120                 125             


Tyr Arg Ser Gly Ser His Arg Pro His Thr Glu Val Phe Pro Tyr Ile 
    130                 135                 140                 


Leu Ala Asp Asp Lys Trp His Lys Leu Ser Leu Ala Ile Ser Ala Ser 
145                 150                 155                 160 


His Leu Ile Leu His Ile Asp Cys Asn Lys Ile Tyr Glu Arg Val Val 
                165                 170                 175     


Glu Lys Pro Ser Thr Asp Leu Pro Leu Gly Thr Thr Phe Trp Leu Gly 
            180                 185                 190         


Gln Arg Asn Asn Ala His Gly Tyr Phe Lys Gly Ile Met Gln Asp Val 
        195                 200                 205             


Gln Leu Leu Val Met Pro Gln Gly Phe Ile Ala Gln Cys Pro Asp Leu 
    210                 215                 220                 


Asn Arg Thr Cys Pro Thr Cys Asn Asp Phe His Gly Leu Val Gln Lys 
225                 230                 235                 240 


Ile Met Glu Leu Gln Asp Ile Leu Ala Lys Thr Ser Ala Lys Leu Ser 
                245                 250                 255     


Arg Ala Glu Gln Arg Met Asn Arg Leu Asp Gln Cys Tyr Cys Glu Arg 
            260                 265                 270         


Thr Cys Thr Met Lys Gly Thr Thr Tyr Arg Glu Phe Glu Ser Trp Ile 
        275                 280                 285             


Asp Gly Cys Lys Asn Cys Thr Cys Leu Asn Gly Thr Ile Gln Cys Glu 
    290                 295                 300                 


Thr Leu Ile Cys Pro Asn Pro Asp Cys Pro Leu Lys Ser Ala Leu Ala 
305                 310                 315                 320 


Tyr Val Asp Gly Lys Cys Cys Lys Glu Cys Lys Ser Ile Cys Gln Phe 
                325                 330                 335     


Gln Gly Arg Thr Tyr Phe Glu Gly Glu Arg Asn Thr Val Tyr Ser Ser 
            340                 345                 350         


Ser Gly Val Cys Val Leu Tyr Glu Cys Lys Asp Gln Thr Met Lys Leu 
        355                 360                 365             


Val Glu Ser Ser Gly Cys Pro Ala Leu Asp Cys Pro Glu Ser His Gln 
    370                 375                 380                 


Ile Thr Leu Ser His Ser Cys Cys Lys Val Cys Lys Gly Tyr Asp Phe 
385                 390                 395                 400 


Cys Ser Glu Arg His Asn Cys Met Glu Asn Ser Ile Cys Arg Asn Leu 
                405                 410                 415     


Asn Asp Arg Ala Val Cys Ser Cys Arg Asp Gly Phe Arg Ala Leu Arg 
            420                 425                 430         


Glu Asp Asn Ala Tyr Cys Glu Asp Ile Asp Glu Cys Ala Glu Gly Arg 
        435                 440                 445             


His Tyr Cys Arg Glu Asn Thr Met Cys Val Asn Thr Pro Gly Ser Phe 
    450                 455                 460                 


Met Cys Ile Cys Lys Thr Gly Tyr Ile Arg Ile Asp Asp Tyr Ser Cys 
465                 470                 475                 480 


Thr Glu His Asp Glu Cys Ile Thr Asn Gln His Asn Cys Asp Glu Asn 
                485                 490                 495     


Ala Leu Cys Phe Asn Thr Val Gly Gly His Asn Cys Val Cys Lys Pro 
            500                 505                 510         


Gly Tyr Thr Gly Asn Gly Thr Thr Cys Lys Ala Phe Cys Lys Asp Gly 
        515                 520                 525             


Cys Arg Asn Gly Gly Ala Cys Ile Ala Ala Asn Val Cys Ala Cys Pro 
    530                 535                 540                 


Gln Gly Phe Thr Gly Pro Ser Cys Glu Thr Asp Ile Asp Glu Cys Ser 
545                 550                 555                 560 


Asp Gly Phe Val Gln Cys Asp Ser Arg Ala Asn Cys Ile Asn Leu Pro 
                565                 570                 575     


Gly Trp Tyr His Cys Glu Cys Arg Asp Gly Tyr His Asp Asn Gly Met 
            580                 585                 590         


Phe Ser Pro Ser Gly Glu Ser Cys Glu Asp Ile Asp Glu Cys Gly Thr 
        595                 600                 605             


Gly Arg His Ser Cys Ala Asn Asp Thr Ile Cys Phe Asn Leu Asp Gly 
    610                 615                 620                 


Gly Tyr Asp Cys Arg Cys Pro His Gly Lys Asn Cys Thr Gly Asp Cys 
625                 630                 635                 640 


Ile His Asp Gly Lys Val Lys His Asn Gly Gln Ile Trp Val Leu Glu 
                645                 650                 655     


Asn Asp Arg Cys Ser Val Cys Ser Cys Gln Asn Gly Phe Val Met Cys 
            660                 665                 670         


Arg Arg Met Val Cys Asp Cys Glu Asn Pro Thr Val Asp Leu Phe Cys 
        675                 680                 685             


Cys Pro Glu Cys Asp Pro Arg Leu Ser Ser Gln Cys Leu His Gln Asn 
    690                 695                 700                 


Gly Glu Thr Leu Tyr Asn Ser Gly Asp Thr Trp Val Gln Asn Cys Gln 
705                 710                 715                 720 


Gln Cys Arg Cys Leu Gln Gly Glu Val Asp Cys Trp Pro Leu Pro Cys 
                725                 730                 735     


Pro Asp Val Glu Cys Glu Phe Ser Ile Leu Pro Glu Asn Glu Cys Cys 
            740                 745                 750         


Pro Arg Cys Val Thr Asp Pro Cys Gln Ala Asp Thr Ile Arg Asn Asp 
        755                 760                 765             


Ile Thr Lys Thr Cys Leu Asp Glu Met Asn Val Val Arg Phe Thr Gly 
    770                 775                 780                 


Ser Ser Trp Ile Lys His Gly Thr Glu Cys Thr Leu Cys Gln Cys Lys 
785                 790                 795                 800 


Asn Gly His Ile Cys Cys Ser Val Asp Pro Gln Cys Leu Gln Glu Leu 
                805                 810                 815     


<210>  4254
<211>  333
<212>  PRT
<213>  homo sapiens

<400>  4254

Met Pro Leu Gly Leu Gly Arg Arg Lys Lys Ala Pro Pro Leu Val Glu 
1               5                   10                  15      


Asn Glu Glu Ala Glu Pro Gly Arg Gly Gly Leu Gly Val Gly Glu Pro 
            20                  25                  30          


Gly Pro Leu Gly Gly Gly Gly Ser Gly Gly Pro Gln Met Gly Leu Pro 
        35                  40                  45              


Pro Pro Pro Pro Ala Leu Arg Pro Arg Leu Val Phe His Thr Gln Leu 
    50                  55                  60                  


Ala His Gly Ser Pro Thr Gly Arg Ile Glu Gly Phe Thr Asn Val Lys 
65                  70                  75                  80  


Glu Leu Tyr Gly Lys Ile Ala Glu Ala Phe Arg Leu Pro Thr Ala Glu 
                85                  90                  95      


Val Met Phe Cys Thr Leu Asn Thr His Lys Val Asp Met Asp Lys Leu 
            100                 105                 110         


Leu Gly Gly Gln Ile Gly Leu Glu Asp Phe Ile Phe Ala His Val Lys 
        115                 120                 125             


Gly Gln Arg Lys Glu Val Glu Val Phe Lys Ser Glu Asp Ala Leu Gly 
    130                 135                 140                 


Leu Thr Ile Thr Asp Asn Gly Ala Gly Tyr Ala Phe Ile Lys Arg Ile 
145                 150                 155                 160 


Lys Glu Gly Ser Val Ile Asp His Ile His Leu Ile Ser Val Gly Asp 
                165                 170                 175     


Met Ile Glu Ala Ile Asn Gly Gln Ser Leu Leu Gly Cys Arg His Tyr 
            180                 185                 190         


Glu Val Ala Arg Leu Leu Lys Glu Leu Pro Arg Gly Arg Thr Phe Thr 
        195                 200                 205             


Leu Lys Leu Thr Glu Pro Arg Lys Ala Phe Asp Met Ile Ser Gln Arg 
    210                 215                 220                 


Ser Ala Gly Gly Arg Pro Gly Ser Gly Pro Gln Leu Gly Thr Gly Arg 
225                 230                 235                 240 


Gly Thr Leu Arg Leu Arg Ser Arg Gly Pro Ala Thr Val Glu Asp Leu 
                245                 250                 255     


Pro Ser Ala Phe Glu Glu Lys Ala Ile Glu Lys Val Asp Asp Leu Leu 
            260                 265                 270         


Glu Ser Tyr Met Gly Ile Arg Asp Thr Glu Leu Ala Ala Thr Met Val 
        275                 280                 285             


Glu Leu Gly Lys Asp Lys Arg Asn Pro Asp Glu Leu Ala Glu Ala Leu 
    290                 295                 300                 


Asp Glu Arg Leu Gly Asp Phe Ala Phe Pro Asp Glu Phe Val Phe Asp 
305                 310                 315                 320 


Val Trp Gly Ala Ile Gly Asp Ala Lys Val Gly Arg Tyr 
                325                 330             


<210>  4255
<211>  236
<212>  PRT
<213>  homo sapiens

<400>  4255

Met Phe Cys Thr Leu Asn Thr His Lys Val Asp Met Asp Lys Leu Leu 
1               5                   10                  15      


Gly Gly Gln Ile Gly Leu Glu Asp Phe Ile Phe Ala His Val Lys Gly 
            20                  25                  30          


Gln Arg Lys Glu Val Glu Val Phe Lys Ser Glu Asp Ala Leu Gly Leu 
        35                  40                  45              


Thr Ile Thr Asp Asn Gly Ala Gly Tyr Ala Phe Ile Lys Arg Ile Lys 
    50                  55                  60                  


Glu Gly Ser Val Ile Asp His Ile His Leu Ile Ser Val Gly Asp Met 
65                  70                  75                  80  


Ile Glu Ala Ile Asn Gly Gln Ser Leu Leu Gly Cys Arg His Tyr Glu 
                85                  90                  95      


Val Ala Arg Leu Leu Lys Glu Leu Pro Arg Gly Arg Thr Phe Thr Leu 
            100                 105                 110         


Lys Leu Thr Glu Pro Arg Lys Ala Phe Asp Met Ile Ser Gln Arg Ser 
        115                 120                 125             


Ala Gly Gly Arg Pro Gly Ser Gly Pro Gln Leu Gly Thr Gly Arg Gly 
    130                 135                 140                 


Thr Leu Arg Leu Arg Ser Arg Gly Pro Ala Thr Val Glu Asp Leu Pro 
145                 150                 155                 160 


Ser Ala Phe Glu Glu Lys Ala Ile Glu Lys Val Asp Asp Leu Leu Glu 
                165                 170                 175     


Ser Tyr Met Gly Ile Arg Asp Thr Glu Leu Ala Ala Thr Met Val Glu 
            180                 185                 190         


Leu Gly Lys Asp Lys Arg Asn Pro Asp Glu Leu Ala Glu Ala Leu Asp 
        195                 200                 205             


Glu Arg Leu Gly Asp Phe Ala Phe Pro Asp Glu Phe Val Phe Asp Val 
    210                 215                 220                 


Trp Gly Ala Ile Gly Asp Ala Lys Val Gly Arg Tyr 
225                 230                 235     


<210>  4256
<211>  477
<212>  PRT
<213>  homo sapiens

<400>  4256

Met Ala Asn Met Gln Gly Leu Val Glu Arg Leu Glu Arg Ala Val Ser 
1               5                   10                  15      


Arg Leu Glu Ser Leu Ser Ala Glu Ser His Arg Pro Pro Gly Asn Cys 
            20                  25                  30          


Gly Glu Val Asn Gly Val Ile Ala Gly Val Ala Pro Ser Val Glu Ala 
        35                  40                  45              


Phe Asp Lys Leu Met Asp Ser Met Val Ala Glu Phe Leu Lys Asn Ser 
    50                  55                  60                  


Arg Ile Leu Ala Gly Asp Val Glu Thr His Ala Glu Met Val His Ser 
65                  70                  75                  80  


Ala Phe Gln Ala Gln Arg Ala Phe Leu Leu Met Ala Ser Gln Tyr Gln 
                85                  90                  95      


Gln Pro His Glu Asn Asp Val Ala Ala Leu Leu Lys Pro Ile Ser Glu 
            100                 105                 110         


Lys Ile Gln Glu Ile Gln Thr Phe Arg Glu Arg Asn Arg Gly Ser Asn 
        115                 120                 125             


Met Phe Asn His Leu Ser Ala Val Ser Glu Ser Ile Pro Ala Leu Gly 
    130                 135                 140                 


Trp Ile Ala Val Ser Pro Lys Pro Gly Pro Tyr Val Lys Glu Met Asn 
145                 150                 155                 160 


Asp Ala Ala Thr Phe Tyr Thr Asn Arg Val Leu Lys Asp Tyr Lys His 
                165                 170                 175     


Ser Asp Leu Arg His Val Asp Trp Val Lys Ser Tyr Leu Asn Ile Trp 
            180                 185                 190         


Ser Glu Leu Gln Ala Tyr Ile Lys Glu His His Thr Thr Gly Leu Thr 
        195                 200                 205             


Trp Ser Lys Thr Gly Pro Val Ala Ser Thr Val Ser Ala Phe Ser Val 
    210                 215                 220                 


Leu Ser Ser Gly Pro Gly Leu Pro Pro Pro Pro Pro Pro Leu Pro Pro 
225                 230                 235                 240 


Pro Gly Pro Pro Pro Leu Phe Glu Asn Glu Gly Lys Lys Glu Glu Ser 
                245                 250                 255     


Ser Pro Ser Arg Ser Ala Leu Phe Ala Gln Leu Asn Gln Gly Glu Ala 
            260                 265                 270         


Ile Thr Lys Gly Leu Arg His Val Thr Asp Asp Gln Lys Thr Tyr Lys 
        275                 280                 285             


Asn Pro Ser Leu Arg Ala Gln Gly Gly Gln Thr Gln Ser Pro Thr Lys 
    290                 295                 300                 


Ser His Thr Pro Ser Pro Thr Ser Pro Lys Ser Tyr Pro Ser Gln Lys 
305                 310                 315                 320 


His Ala Pro Val Leu Glu Leu Glu Gly Lys Lys Trp Arg Val Glu Tyr 
                325                 330                 335     


Gln Glu Asp Arg Asn Asp Leu Val Ile Ser Glu Thr Glu Leu Lys Gln 
            340                 345                 350         


Val Ala Tyr Ile Phe Lys Cys Glu Lys Ser Thr Ile Gln Ile Lys Gly 
        355                 360                 365             


Lys Val Asn Ser Ile Ile Ile Asp Asn Cys Lys Lys Leu Gly Leu Val 
    370                 375                 380                 


Phe Asp Asn Val Val Gly Ile Val Glu Val Ile Asn Ser Gln Asp Ile 
385                 390                 395                 400 


Gln Ile Gln Val Met Gly Arg Val Pro Thr Ile Ser Ile Asn Lys Thr 
                405                 410                 415     


Glu Gly Cys His Ile Tyr Leu Ser Glu Asp Ala Leu Asp Cys Glu Ile 
            420                 425                 430         


Val Ser Ala Lys Ser Ser Glu Met Asn Ile Leu Ile Pro Gln Asp Gly 
        435                 440                 445             


Asp Tyr Arg Glu Phe Pro Ile Pro Glu Gln Phe Lys Thr Ala Trp Asp 
    450                 455                 460                 


Gly Ser Lys Leu Ile Thr Glu Pro Ala Glu Ile Met Ala 
465                 470                 475         


<210>  4257
<211>  277
<212>  PRT
<213>  homo sapiens

<400>  4257

Met Pro Arg Leu His Asp His Phe Trp Ser Cys Ser Cys Ala His Ser 
1               5                   10                  15      


Ala Arg Arg Arg Gly Pro Pro Arg Ala Ser Ala Ala Gly Leu Ala Ala 
            20                  25                  30          


Lys Val Gly Glu Met Ile Asn Val Ser Val Ser Gly Pro Ser Leu Leu 
        35                  40                  45              


Ala Ala His Gly Ala Pro Asp Ala Asp Pro Ala Pro Arg Gly Arg Ser 
    50                  55                  60                  


Ala Ala Met Ser Gly Pro Glu Pro Gly Ser Pro Tyr Pro Asn Thr Trp 
65                  70                  75                  80  


His His Arg Leu Leu Gln Arg Ser Leu Val Leu Phe Ser Val Gly Val 
                85                  90                  95      


Val Leu Ala Leu Val Leu Asn Leu Leu Gln Ile Gln Arg Asn Val Thr 
            100                 105                 110         


Leu Phe Pro Glu Glu Val Ile Ala Thr Ile Phe Ser Ser Ala Trp Trp 
        115                 120                 125             


Val Pro Pro Cys Cys Gly Thr Ala Ala Ala Val Val Gly Leu Leu Tyr 
    130                 135                 140                 


Pro Cys Ile Asp Ser His Leu Gly Glu Pro His Lys Phe Lys Arg Glu 
145                 150                 155                 160 


Trp Ala Ser Val Met Arg Cys Ile Ala Val Phe Val Gly Ile Asn His 
                165                 170                 175     


Ala Ser Ala Lys Leu Asp Phe Ala Asn Asn Val Gln Leu Ser Leu Thr 
            180                 185                 190         


Leu Ala Ala Leu Ser Leu Gly Leu Trp Trp Thr Phe Asp Arg Ser Arg 
        195                 200                 205             


Ser Gly Leu Gly Leu Gly Ile Thr Ile Ala Phe Leu Ala Thr Leu Ile 
    210                 215                 220                 


Thr Gln Phe Leu Val Tyr Asn Gly Val Tyr Gln Tyr Thr Ser Pro Asp 
225                 230                 235                 240 


Phe Leu Tyr Ile Arg Ser Trp Leu Pro Cys Ile Phe Phe Ser Gly Gly 
                245                 250                 255     


Val Thr Val Gly Asn Ile Gly Arg Gln Leu Ala Met Gly Val Pro Glu 
            260                 265                 270         


Lys Pro His Ser Asp 
        275         


<210>  4258
<211>  164
<212>  PRT
<213>  homo sapiens

<400>  4258

Met Pro Arg Leu His Asp His Phe Trp Ser Cys Ser Cys Ala His Ser 
1               5                   10                  15      


Ala Arg Arg Arg Gly Pro Pro Arg Ala Ser Ala Ala Gly Leu Ala Ala 
            20                  25                  30          


Lys Val Gly Glu Met Ile Asn Val Ser Val Ser Gly Pro Ser Leu Leu 
        35                  40                  45              


Ala Ala His Gly Ala Pro Asp Ala Asp Pro Ala Pro Arg Gly Arg Ser 
    50                  55                  60                  


Ala Ala Met Ser Gly Pro Glu Pro Gly Ser Pro Tyr Pro Asn Thr Trp 
65                  70                  75                  80  


His His Arg Leu Leu Gln Arg Ser Leu Val Leu Phe Ser Val Gly Val 
                85                  90                  95      


Val Leu Ala Leu Val Leu Asn Leu Leu Gln Ile Gln Arg Asn Val Thr 
            100                 105                 110         


Leu Phe Pro Glu Glu Val Ile Ala Thr Ile Phe Ser Ser Ala Trp Trp 
        115                 120                 125             


Val Pro Pro Cys Cys Gly Thr Ala Ala Gly Ile His Pro Gln Ile Ser 
    130                 135                 140                 


Ser Ile Phe Val Leu Gly Ser Leu Val Tyr Phe Ser Gln Glu Ala Ser 
145                 150                 155                 160 


Arg Trp Gly Thr 
                


<210>  4259
<211>  140
<212>  PRT
<213>  homo sapiens

<400>  4259

Met Gly Pro Arg Arg Arg Ser Arg Lys Pro Glu Ala Pro Arg Arg Arg 
1               5                   10                  15      


Ser Pro Ser Pro Thr Pro Thr Pro Gly Pro Ser Arg Arg Gly Pro Ser 
            20                  25                  30          


Leu Gly Ala Ser Ser His Gln His Ser Arg Arg Arg Gln Gly Trp Leu 
        35                  40                  45              


Lys Glu Ile Arg Lys Leu Gln Lys Ser Thr His Leu Leu Ile Arg Lys 
    50                  55                  60                  


Leu Pro Phe Ser Arg Leu Ala Arg Glu Ile Cys Val Lys Phe Thr Arg 
65                  70                  75                  80  


Gly Val Asp Phe Asn Trp Gln Ala Gln Ala Leu Leu Ala Leu Gln Glu 
                85                  90                  95      


Ala Ala Glu Ala Phe Leu Val His Leu Phe Glu Asp Ala Tyr Leu Leu 
            100                 105                 110         


Thr Leu His Ala Gly Arg Val Thr Leu Phe Pro Lys Asp Val Gln Leu 
        115                 120                 125             


Ala Arg Arg Ile Arg Gly Leu Glu Glu Gly Leu Gly 
    130                 135                 140 


<210>  4260
<211>  178
<212>  PRT
<213>  homo sapiens

<400>  4260

Met Pro Arg Leu His Asp His Phe Trp Ser Cys Ser Cys Ala His Ser 
1               5                   10                  15      


Ala Arg Arg Arg Gly Pro Pro Arg Ala Ser Ala Lys Leu Asp Phe Ala 
            20                  25                  30          


Asn Asn Val Gln Leu Ser Leu Thr Leu Ala Ala Leu Ser Leu Gly Leu 
        35                  40                  45              


Trp Trp Thr Phe Asp Arg Ser Arg Ser Gly Leu Gly Leu Gly Ile Thr 
    50                  55                  60                  


Ile Ala Phe Leu Ala Thr Leu Ile Thr Gln Phe Leu Val Tyr Asn Gly 
65                  70                  75                  80  


Val Tyr Gln Tyr Thr Ser Pro Asp Phe Leu Tyr Ile Arg Ser Trp Leu 
                85                  90                  95      


Pro Cys Ile Phe Phe Ser Gly Gly Val Thr Val Gly Asn Ile Gly Arg 
            100                 105                 110         


Gln Leu Ala Met Leu Ile Pro Phe Cys Glu Glu Leu Asn Leu Lys Thr 
        115                 120                 125             


Thr Trp Leu Phe His Lys Thr Arg Ser Asn Tyr Arg Val Phe Leu Lys 
    130                 135                 140                 


Ser Pro Ile Val Ile Glu Ser Ser Lys Pro Pro Ile Leu Arg Ala Arg 
145                 150                 155                 160 


Lys Ile Leu Glu Glu Asn Leu Thr Val Asp Tyr Asp Lys Asp Tyr Leu 
                165                 170                 175     


Phe Ser 
        


<210>  4261
<211>  510
<212>  PRT
<213>  homo sapiens

<400>  4261

Met Pro Arg Gly Phe Leu Val Lys Arg Ser Lys Lys Ser Thr Pro Val 
1               5                   10                  15      


Ser Tyr Arg Val Arg Gly Gly Glu Asp Gly Asp Arg Ala Leu Leu Leu 
            20                  25                  30          


Ser Pro Ser Cys Gly Gly Ala Arg Ala Glu Pro Pro Ala Pro Ser Pro 
        35                  40                  45              


Val Pro Gly Pro Leu Pro Pro Pro Pro Pro Ala Glu Arg Ala His Ala 
    50                  55                  60                  


Ala Leu Ala Ala Ala Leu Ala Cys Ala Pro Gly Pro Gln Pro Pro Pro 
65                  70                  75                  80  


Gln Gly Pro Arg Ala Ala His Phe Gly Asn Pro Glu Ala Ala His Pro 
                85                  90                  95      


Ala Pro Leu Tyr Ser Pro Thr Arg Pro Val Ser Arg Glu His Glu Lys 
            100                 105                 110         


His Lys Tyr Phe Glu Arg Ser Phe Asn Leu Gly Ser Pro Val Ser Ala 
        115                 120                 125             


Glu Ser Phe Pro Thr Pro Ala Ala Leu Leu Gly Gly Gly Gly Gly Gly 
    130                 135                 140                 


Gly Ala Ser Gly Ala Gly Gly Gly Gly Thr Cys Gly Gly Asp Pro Leu 
145                 150                 155                 160 


Leu Phe Ala Pro Ala Glu Leu Lys Met Gly Thr Ala Phe Ser Ala Gly 
                165                 170                 175     


Ala Glu Ala Ala Arg Gly Pro Gly Pro Gly Pro Pro Leu Pro Pro Ala 
            180                 185                 190         


Ala Ala Leu Arg Pro Pro Gly Lys Arg Pro Pro Pro Pro Thr Ala Ala 
        195                 200                 205             


Glu Pro Pro Ala Lys Ala Val Lys Ala Pro Gly Ala Lys Lys Pro Lys 
    210                 215                 220                 


Ala Ile Arg Lys Leu His Phe Glu Asp Glu Val Thr Thr Ser Pro Val 
225                 230                 235                 240 


Leu Gly Leu Lys Ile Lys Glu Gly Pro Val Glu Ala Pro Arg Gly Arg 
                245                 250                 255     


Ala Gly Gly Ala Ala Arg Pro Leu Gly Glu Phe Ile Cys Gln Leu Cys 
            260                 265                 270         


Lys Glu Glu Tyr Ala Asp Pro Phe Ala Leu Ala Gln His Lys Cys Ser 
        275                 280                 285             


Arg Ile Val Arg Val Glu Tyr Arg Cys Pro Glu Cys Ala Lys Val Phe 
    290                 295                 300                 


Ser Cys Pro Ala Asn Leu Ala Ser His Arg Arg Trp His Lys Pro Arg 
305                 310                 315                 320 


Pro Ala Pro Ala Ala Ala Arg Ala Pro Glu Pro Glu Ala Ala Ala Arg 
                325                 330                 335     


Ala Glu Ala Arg Glu Ala Pro Gly Gly Gly Ser Asp Arg Asp Thr Pro 
            340                 345                 350         


Ser Pro Gly Gly Val Ser Glu Ser Gly Ser Glu Asp Gly Leu Tyr Glu 
        355                 360                 365             


Cys His His Cys Ala Lys Lys Phe Arg Arg Gln Ala Tyr Leu Arg Lys 
    370                 375                 380                 


His Leu Leu Ala His His Gln Ala Leu Gln Ala Lys Gly Ala Pro Leu 
385                 390                 395                 400 


Ala Pro Pro Ala Glu Asp Leu Leu Ala Leu Tyr Pro Gly Pro Asp Glu 
                405                 410                 415     


Lys Ala Pro Gln Glu Ala Ala Gly Asp Gly Glu Gly Ala Gly Val Leu 
            420                 425                 430         


Gly Leu Ser Ala Ser Ala Glu Cys His Leu Cys Pro Val Cys Gly Glu 
        435                 440                 445             


Ser Phe Ala Ser Lys Gly Ala Gln Glu Arg His Leu Arg Leu Leu His 
    450                 455                 460                 


Ala Ala Gln Val Phe Pro Cys Lys Tyr Cys Pro Ala Thr Phe Tyr Ser 
465                 470                 475                 480 


Ser Pro Gly Leu Thr Arg His Ile Asn Lys Cys His Pro Ser Glu Asn 
                485                 490                 495     


Arg Gln Val Ile Leu Leu Gln Val Pro Val Arg Pro Ala Cys 
            500                 505                 510 


<210>  4262
<211>  1115
<212>  PRT
<213>  homo sapiens

<400>  4262

Met Pro Glu Asp Gln Val Gly Lys Leu Glu Ala Thr Glu Asn Thr Ile 
1               5                   10                  15      


Ser Ala Met Ala Ala Ala Ala Ala Glu Gln Gln Gln Phe Tyr Leu Leu 
            20                  25                  30          


Leu Gly Asn Leu Leu Ser Pro Asp Asn Val Val Arg Lys Gln Ala Glu 
        35                  40                  45              


Glu Thr Tyr Glu Asn Ile Pro Gly Gln Ser Lys Ile Thr Phe Leu Leu 
    50                  55                  60                  


Gln Ala Ile Arg Asn Thr Thr Ala Ala Glu Glu Ala Arg Gln Met Ala 
65                  70                  75                  80  


Ala Val Leu Leu Arg Arg Leu Leu Ser Ser Ala Phe Asp Glu Val Tyr 
                85                  90                  95      


Pro Ala Leu Pro Ser Asp Val Gln Thr Ala Ile Lys Ser Glu Leu Leu 
            100                 105                 110         


Met Ile Ile Gln Met Glu Thr Gln Ser Ser Met Arg Lys Lys Val Cys 
        115                 120                 125             


Asp Ile Ala Ala Glu Leu Ala Arg Asn Leu Ile Asp Glu Asp Gly Asn 
    130                 135                 140                 


Asn Gln Trp Pro Glu Gly Leu Lys Phe Leu Phe Asp Ser Val Ser Ser 
145                 150                 155                 160 


Gln Asn Val Gly Leu Arg Glu Ala Ala Leu His Ile Phe Trp Asn Phe 
                165                 170                 175     


Pro Gly Ile Phe Gly Asn Gln Gln Gln His Tyr Leu Asp Val Ile Lys 
            180                 185                 190         


Arg Met Leu Val Gln Cys Met Gln Asp Gln Glu His Pro Ser Ile Arg 
        195                 200                 205             


Thr Leu Ser Ala Arg Ala Thr Ala Ala Phe Ile Leu Ala Asn Glu His 
    210                 215                 220                 


Asn Val Ala Leu Phe Lys His Phe Ala Asp Leu Leu Pro Gly Phe Leu 
225                 230                 235                 240 


Gln Ala Val Asn Asp Ser Cys Tyr Gln Asn Asp Asp Ser Val Leu Lys 
                245                 250                 255     


Ser Leu Val Glu Ile Ala Asp Thr Val Pro Lys Tyr Leu Arg Pro His 
            260                 265                 270         


Leu Glu Ala Thr Leu Gln Leu Ser Leu Lys Leu Cys Gly Asp Thr Ser 
        275                 280                 285             


Leu Asn Asn Met Gln Arg Gln Leu Ala Leu Glu Val Ile Val Thr Leu 
    290                 295                 300                 


Ser Glu Thr Ala Ala Ala Met Leu Arg Lys His Thr Asn Ile Val Ala 
305                 310                 315                 320 


Gln Thr Ile Pro Gln Met Leu Ala Met Met Val Asp Leu Glu Glu Asp 
                325                 330                 335     


Glu Asp Trp Ala Asn Ala Asp Glu Leu Glu Asp Asp Asp Phe Asp Ser 
            340                 345                 350         


Asn Ala Val Ala Gly Glu Ser Ala Leu Asp Arg Met Ala Cys Gly Leu 
        355                 360                 365             


Gly Gly Lys Leu Val Leu Pro Met Ile Lys Glu His Ile Met Gln Met 
    370                 375                 380                 


Leu Gln Asn Pro Asp Trp Lys Tyr Arg His Ala Gly Leu Met Ala Leu 
385                 390                 395                 400 


Ser Ala Ile Gly Glu Gly Cys His Gln Gln Met Glu Gly Ile Leu Asn 
                405                 410                 415     


Glu Ile Val Asn Phe Val Leu Leu Phe Leu Gln Asp Pro His Pro Arg 
            420                 425                 430         


Val Arg Tyr Ala Ala Cys Asn Ala Val Gly Gln Met Ala Thr Asp Phe 
        435                 440                 445             


Ala Pro Gly Phe Gln Lys Lys Phe His Glu Lys Val Ile Ala Ala Leu 
    450                 455                 460                 


Leu Gln Thr Met Glu Asp Gln Gly Asn Gln Arg Val Gln Ala His Ala 
465                 470                 475                 480 


Ala Ala Ala Leu Ile Asn Phe Thr Glu Asp Cys Pro Lys Ser Leu Leu 
                485                 490                 495     


Ile Pro Tyr Leu Asp Asn Leu Val Lys His Leu His Ser Ile Met Val 
            500                 505                 510         


Leu Lys Leu Gln Glu Leu Ile Gln Lys Gly Thr Lys Leu Val Leu Glu 
        515                 520                 525             


Gln Val Val Thr Ser Ile Ala Ser Val Ala Asp Thr Ala Glu Glu Lys 
    530                 535                 540                 


Phe Val Pro Tyr Tyr Asp Leu Phe Met Pro Ser Leu Lys His Ile Val 
545                 550                 555                 560 


Glu Asn Ala Val Gln Lys Glu Leu Arg Leu Leu Arg Gly Lys Thr Ile 
                565                 570                 575     


Glu Cys Ile Ser Leu Ile Gly Leu Ala Val Gly Lys Glu Lys Phe Met 
            580                 585                 590         


Gln Asp Ala Ser Asp Val Met Gln Leu Leu Leu Lys Thr Gln Thr Asp 
        595                 600                 605             


Phe Asn Asp Met Glu Asp Asp Asp Pro Gln Ile Ser Tyr Met Ile Ser 
    610                 615                 620                 


Ala Trp Ala Arg Met Cys Lys Ile Leu Gly Lys Glu Phe Gln Gln Tyr 
625                 630                 635                 640 


Leu Pro Val Val Met Gly Pro Leu Met Lys Thr Ala Ser Ile Lys Pro 
                645                 650                 655     


Glu Val Ala Leu Leu Asp Thr Gln Asp Met Glu Asn Met Ser Asp Asp 
            660                 665                 670         


Asp Gly Trp Glu Phe Val Asn Leu Gly Asp Gln Gln Ser Phe Gly Ile 
        675                 680                 685             


Lys Thr Ala Gly Leu Glu Glu Lys Ser Thr Ala Cys Gln Met Leu Val 
    690                 695                 700                 


Cys Tyr Ala Lys Glu Leu Lys Glu Gly Phe Val Glu Tyr Thr Glu Gln 
705                 710                 715                 720 


Val Val Lys Leu Met Val Pro Leu Leu Lys Phe Tyr Phe His Asp Gly 
                725                 730                 735     


Val Arg Val Ala Ala Ala Glu Ser Met Pro Leu Leu Leu Glu Cys Ala 
            740                 745                 750         


Arg Val Arg Gly Pro Glu Tyr Leu Thr Gln Met Trp His Phe Met Cys 
        755                 760                 765             


Asp Ala Leu Ile Lys Ala Ile Gly Thr Glu Pro Asp Ser Asp Val Leu 
    770                 775                 780                 


Ser Glu Ile Met His Ser Phe Ala Lys Cys Ile Glu Val Met Gly Asp 
785                 790                 795                 800 


Gly Cys Leu Asn Asn Glu His Phe Glu Glu Leu Gly Gly Ile Leu Lys 
                805                 810                 815     


Ala Lys Leu Glu Glu His Phe Lys Asn Gln Glu Leu Arg Gln Val Lys 
            820                 825                 830         


Arg Gln Asp Glu Asp Tyr Asp Glu Gln Val Glu Glu Ser Leu Gln Asp 
        835                 840                 845             


Glu Asp Asp Asn Asp Val Tyr Ile Leu Thr Lys Val Ser Asp Ile Leu 
    850                 855                 860                 


His Ser Ile Phe Ser Ser Tyr Lys Glu Lys Val Leu Pro Trp Phe Glu 
865                 870                 875                 880 


Gln Leu Leu Pro Leu Ile Val Asn Leu Ile Cys Pro His Arg Pro Trp 
                885                 890                 895     


Pro Asp Arg Gln Trp Gly Leu Cys Ile Phe Asp Asp Val Ile Glu His 
            900                 905                 910         


Cys Ser Pro Ala Ser Phe Lys Tyr Ala Glu Tyr Phe Leu Arg Pro Met 
        915                 920                 925             


Leu Gln Tyr Val Cys Asp Asn Ser Pro Glu Val Arg Gln Ala Ala Ala 
    930                 935                 940                 


Tyr Gly Leu Gly Val Met Ala Gln Tyr Gly Gly Asp Asn Tyr Arg Pro 
945                 950                 955                 960 


Phe Cys Thr Glu Ala Leu Pro Leu Leu Val Arg Val Ile Gln Ser Ala 
                965                 970                 975     


Asp Ser Lys Thr Lys Glu Asn Val Asn Ala Thr Glu Asn Cys Ile Ser 
            980                 985                 990         


Ala Val Gly Lys Ile Met Lys Phe  Lys Pro Asp Cys Val  Asn Val Glu 
        995                 1000                 1005             


Glu Val  Leu Pro His Trp Leu  Ser Trp Leu Pro Leu  His Glu Asp 
    1010                 1015                 1020             


Lys Glu  Glu Ala Val Gln Thr  Phe Asn Tyr Leu Cys  Asp Leu Ile 
    1025                 1030                 1035             


Glu Ser  Asn His Pro Ile Val  Leu Gly Pro Asn Asn  Thr Asn Leu 
    1040                 1045                 1050             


Pro Lys  Ile Phe Ser Ile Ile  Ala Glu Gly Glu Met  His Glu Ala 
    1055                 1060                 1065             


Ile Lys  His Glu Asp Pro Cys  Ala Lys Arg Leu Ala  Asn Val Val 
    1070                 1075                 1080             


Arg Gln  Val Gln Thr Ser Gly  Gly Leu Trp Thr Glu  Cys Ile Ala 
    1085                 1090                 1095             


Gln Leu  Ser Pro Glu Gln Gln  Ala Ala Ile Gln Glu  Leu Leu Asn 
    1100                 1105                 1110             


Ser Ala  
    1115 


<210>  4263
<211>  887
<212>  PRT
<213>  homo sapiens

<400>  4263

Met Ser Leu Phe Lys Ala Arg Asp Trp Trp Ser Thr Ile Leu Gly Asp 
1               5                   10                  15      


Lys Glu Glu Phe Asp Gln Gly Cys Leu Cys Leu Ala Asn Val Asp Asn 
            20                  25                  30          


Ser Gly Asn Gly Gln Asp Lys Ile Ile Val Gly Ser Phe Met Gly Tyr 
        35                  40                  45              


Leu Arg Ile Phe Ser Pro His Pro Ala Lys Thr Gly Asp Gly Ala Gln 
    50                  55                  60                  


Ala Glu Asp Leu Leu Leu Glu Val Asp Leu Arg Asp Pro Val Leu Gln 
65                  70                  75                  80  


Val Glu Val Gly Lys Phe Val Ser Gly Thr Glu Met Leu His Leu Ala 
                85                  90                  95      


Val Leu His Ser Arg Lys Leu Cys Val Tyr Ser Val Ser Gly Thr Leu 
            100                 105                 110         


Gly Asn Val Glu His Gly Asn Gln Cys Gln Met Lys Leu Met Tyr Glu 
        115                 120                 125             


His Asn Leu Gln Arg Thr Ala Cys Asn Met Thr Tyr Gly Ser Phe Gly 
    130                 135                 140                 


Gly Val Lys Gly Arg Asp Leu Ile Cys Ile Gln Ser Met Asp Gly Met 
145                 150                 155                 160 


Leu Met Val Phe Glu Gln Glu Ser Tyr Ala Phe Gly Arg Phe Leu Pro 
                165                 170                 175     


Gly Phe Leu Leu Pro Gly Pro Leu Ala Tyr Ser Ser Arg Thr Asp Ser 
            180                 185                 190         


Phe Leu Thr Val Ser Ser Cys Gln Gln Val Glu Ser Tyr Lys Tyr Gln 
        195                 200                 205             


Val Leu Ala Phe Ala Thr Asp Ala Asp Lys Arg Gln Glu Thr Glu Gln 
    210                 215                 220                 


Gln Lys Leu Gly Ser Gly Lys Arg Leu Val Val Asp Trp Thr Leu Asn 
225                 230                 235                 240 


Ile Gly Glu Gln Ala Leu Asp Ile Cys Ile Val Ser Phe Asn Gln Ser 
                245                 250                 255     


Ala Ser Ser Val Phe Val Leu Gly Glu Arg Asn Phe Phe Cys Leu Lys 
            260                 265                 270         


Asp Asn Gly Gln Ile Arg Phe Met Lys Lys Leu Asp Trp Ser Pro Ser 
        275                 280                 285             


Cys Phe Leu Pro Tyr Cys Ser Val Ser Glu Gly Thr Ile Asn Thr Leu 
    290                 295                 300                 


Ile Gly Asn His Asn Asn Met Leu His Ile Tyr Gln Asp Val Thr Leu 
305                 310                 315                 320 


Lys Trp Ala Thr Gln Leu Pro His Ile Pro Val Ala Val Arg Val Gly 
                325                 330                 335     


Cys Leu His Asp Leu Lys Gly Val Ile Val Thr Leu Ser Asp Asp Gly 
            340                 345                 350         


His Leu Gln Cys Ser Tyr Leu Gly Thr Asp Pro Ser Leu Phe Gln Ala 
        355                 360                 365             


Pro Asn Val Gln Ser Arg Glu Leu Asn Tyr Asp Glu Leu Asp Val Glu 
    370                 375                 380                 


Met Lys Glu Leu Gln Lys Ile Ile Lys Asp Val Asn Lys Ser Gln Gly 
385                 390                 395                 400 


Val Trp Pro Met Thr Glu Arg Glu Asp Asp Leu Asn Val Ser Val Val 
                405                 410                 415     


Val Ser Pro Asn Phe Asp Ser Val Ser Gln Ala Thr Asp Val Glu Val 
            420                 425                 430         


Gly Thr Asp Leu Val Pro Ser Val Thr Val Lys Val Thr Leu Gln Asn 
        435                 440                 445             


Arg Val Ile Leu Gln Lys Ala Lys Leu Ser Val Tyr Val Gln Pro Pro 
    450                 455                 460                 


Leu Glu Leu Thr Cys Asp Gln Phe Thr Phe Glu Phe Met Thr Pro Asp 
465                 470                 475                 480 


Leu Thr Arg Thr Val Ser Phe Ser Val Tyr Leu Lys Arg Ser Tyr Thr 
                485                 490                 495     


Pro Ser Glu Leu Glu Gly Asn Ala Val Val Ser Tyr Ser Arg Pro Thr 
            500                 505                 510         


Asp Arg Asn Pro Asp Gly Ile Pro Arg Val Ile Gln Cys Lys Phe Arg 
        515                 520                 525             


Leu Pro Leu Lys Leu Ile Cys Leu Pro Gly Gln Pro Ser Lys Thr Ala 
    530                 535                 540                 


Ser His Lys Ile Thr Ile Asp Thr Asn Lys Ser Pro Val Ser Leu Leu 
545                 550                 555                 560 


Ser Leu Phe Pro Gly Phe Ala Ser Gln Ser Asp Asp Asp Gln Val Asn 
                565                 570                 575     


Val Met Gly Phe His Phe Leu Gly Gly Ala Arg Ile Thr Val Leu Ala 
            580                 585                 590         


Ser Lys Thr Ser Gln Arg Tyr Arg Ile Gln Ser Glu Gln Phe Glu Asp 
        595                 600                 605             


Leu Trp Leu Ile Thr Asn Glu Leu Ile Leu Arg Leu Gln Glu Tyr Phe 
    610                 615                 620                 


Glu Lys Gln Gly Val Lys Asp Phe Ala Cys Ser Phe Ser Gly Ser Ile 
625                 630                 635                 640 


Pro Leu Gln Glu Tyr Phe Glu Leu Ile Asp His His Phe Glu Leu Arg 
                645                 650                 655     


Ile Asn Gly Glu Lys Leu Glu Glu Leu Leu Ser Glu Arg Ala Val Gln 
            660                 665                 670         


Phe Arg Ala Ile Gln Arg Arg Leu Leu Ala Arg Phe Lys Asp Lys Thr 
        675                 680                 685             


Pro Ala Pro Leu Gln His Leu Asp Thr Leu Leu Asp Gly Thr Tyr Lys 
    690                 695                 700                 


Gln Val Ile Ala Leu Ala Asp Ala Val Glu Glu Asn Gln Gly Asn Leu 
705                 710                 715                 720 


Phe Gln Ser Phe Thr Arg Leu Lys Ser Ala Thr His Leu Val Ile Leu 
                725                 730                 735     


Leu Ile Ala Leu Trp Gln Lys Leu Ser Ala Asp Gln Val Ala Ile Leu 
            740                 745                 750         


Glu Ala Ala Phe Leu Pro Leu Gln Glu Asp Thr Gln Glu Leu Gly Trp 
        755                 760                 765             


Glu Glu Thr Val Asp Ala Ala Ile Ser His Leu Leu Lys Thr Cys Leu 
    770                 775                 780                 


Ser Lys Ser Ser Lys Glu Gln Ala Leu Asn Leu Asn Ser Gln Leu Asn 
785                 790                 795                 800 


Ile Pro Lys Asp Thr Ser Gln Leu Lys Lys His Ile Thr Leu Leu Cys 
                805                 810                 815     


Asp Arg Leu Ser Lys Gly Gly Arg Leu Cys Leu Ser Thr Asp Ala Ala 
            820                 825                 830         


Ala Pro Gln Thr Met Val Met Pro Gly Gly Cys Thr Thr Ile Pro Glu 
        835                 840                 845             


Ser Asp Leu Glu Glu Arg Ser Val Glu Gln Asp Ser Thr Glu Leu Phe 
    850                 855                 860                 


Thr Asn His Arg His Leu Thr Ala Glu Thr Pro Arg Pro Glu Val Ser 
865                 870                 875                 880 


Pro Leu Gln Gly Val Ser Glu 
                885         


<210>  4264
<211>  1336
<212>  PRT
<213>  homo sapiens

<400>  4264

Met Ala Pro Arg Cys Pro Trp Pro Trp Pro Arg Arg Arg Arg Leu Leu 
1               5                   10                  15      


Asp Val Leu Ala Pro Leu Val Leu Leu Leu Gly Val Arg Ala Ala Ser 
            20                  25                  30          


Ala Glu Pro Glu Arg Ile Ser Glu Glu Val Gly Leu Leu Gln Leu Leu 
        35                  40                  45              


Gly Asp Pro Pro Pro Gln Gln Val Thr Gln Thr Asp Asp Pro Asp Val 
    50                  55                  60                  


Gly Leu Ala Tyr Val Phe Gly Pro Asp Ala Asn Ser Gly Gln Val Ala 
65                  70                  75                  80  


Arg Tyr His Phe Pro Ser Leu Phe Phe Arg Asp Phe Ser Leu Leu Phe 
                85                  90                  95      


His Ile Arg Pro Ala Thr Glu Gly Pro Gly Val Leu Phe Ala Ile Thr 
            100                 105                 110         


Asp Ser Ala Gln Ala Met Val Leu Leu Gly Val Lys Leu Ser Gly Val 
        115                 120                 125             


Gln Asp Gly His Gln Asp Ile Ser Leu Leu Tyr Thr Glu Pro Gly Ala 
    130                 135                 140                 


Gly Gln Thr His Thr Ala Ala Ser Phe Arg Leu Pro Ala Phe Val Gly 
145                 150                 155                 160 


Gln Trp Thr His Leu Ala Leu Ser Val Ala Gly Gly Phe Val Ala Leu 
                165                 170                 175     


Tyr Val Asp Cys Glu Glu Phe Gln Arg Met Pro Leu Ala Arg Ser Ser 
            180                 185                 190         


Arg Gly Leu Glu Leu Glu Pro Gly Ala Gly Leu Phe Val Ala Gln Ala 
        195                 200                 205             


Gly Gly Ala Asp Pro Asp Lys Phe Gln Gly Val Ile Ala Glu Leu Lys 
    210                 215                 220                 


Val Arg Arg Asp Pro Gln Val Ser Pro Met His Cys Leu Asp Glu Glu 
225                 230                 235                 240 


Gly Asp Asp Ser Asp Gly Ala Ser Gly Asp Ser Gly Ser Gly Leu Gly 
                245                 250                 255     


Asp Ala Arg Glu Leu Leu Arg Glu Glu Thr Gly Ala Ala Leu Lys Pro 
            260                 265                 270         


Arg Leu Pro Ala Pro Pro Pro Val Thr Thr Pro Pro Leu Ala Gly Gly 
        275                 280                 285             


Ser Ser Thr Glu Asp Ser Arg Ser Glu Glu Val Glu Glu Gln Thr Thr 
    290                 295                 300                 


Val Ala Ser Leu Gly Ala Gln Thr Leu Pro Gly Ser Asp Ser Val Ser 
305                 310                 315                 320 


Thr Trp Asp Gly Ser Val Arg Thr Pro Gly Gly Arg Val Lys Glu Gly 
                325                 330                 335     


Gly Leu Lys Gly Gln Lys Gly Glu Pro Gly Val Pro Gly Pro Pro Gly 
            340                 345                 350         


Arg Ala Gly Pro Pro Gly Ser Pro Cys Leu Pro Gly Pro Pro Gly Leu 
        355                 360                 365             


Pro Cys Pro Val Ser Pro Leu Gly Pro Ala Gly Pro Ala Leu Gln Thr 
    370                 375                 380                 


Val Pro Gly Pro Gln Gly Pro Pro Gly Pro Pro Gly Arg Asp Gly Thr 
385                 390                 395                 400 


Pro Gly Arg Asp Gly Glu Pro Gly Asp Pro Gly Glu Asp Gly Lys Pro 
                405                 410                 415     


Gly Asp Thr Gly Pro Gln Gly Phe Pro Gly Thr Pro Gly Asp Val Gly 
            420                 425                 430         


Pro Lys Gly Asp Lys Gly Asp Pro Gly Val Gly Glu Arg Gly Pro Pro 
        435                 440                 445             


Gly Pro Gln Gly Pro Pro Gly Pro Pro Gly Pro Ser Phe Arg His Asp 
    450                 455                 460                 


Lys Leu Thr Phe Ile Asp Met Glu Gly Ser Gly Phe Gly Gly Asp Leu 
465                 470                 475                 480 


Glu Ala Leu Arg Gly Pro Arg Gly Phe Pro Gly Pro Pro Gly Pro Pro 
                485                 490                 495     


Gly Val Pro Gly Leu Pro Gly Glu Pro Gly Arg Phe Gly Val Asn Ser 
            500                 505                 510         


Ser Asp Val Pro Gly Pro Ala Gly Leu Pro Gly Val Pro Gly Arg Glu 
        515                 520                 525             


Gly Pro Pro Gly Phe Pro Gly Leu Pro Gly Pro Pro Gly Pro Pro Gly 
    530                 535                 540                 


Arg Glu Gly Pro Pro Gly Arg Thr Gly Gln Lys Gly Ser Leu Gly Glu 
545                 550                 555                 560 


Ala Gly Ala Pro Gly His Lys Gly Ser Lys Gly Ala Pro Gly Pro Ala 
                565                 570                 575     


Gly Ala Arg Gly Glu Ser Gly Leu Ala Gly Ala Pro Gly Pro Ala Gly 
            580                 585                 590         


Pro Pro Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly Pro Gly Leu Pro 
        595                 600                 605             


Ala Gly Phe Asp Asp Met Glu Gly Ser Gly Gly Pro Phe Trp Ser Thr 
    610                 615                 620                 


Ala Arg Ser Ala Asp Gly Pro Gln Gly Pro Pro Gly Leu Pro Gly Leu 
625                 630                 635                 640 


Lys Gly Asp Pro Gly Val Pro Gly Leu Pro Gly Ala Lys Gly Glu Val 
                645                 650                 655     


Gly Ala Asp Gly Val Pro Gly Phe Pro Gly Leu Pro Gly Arg Glu Gly 
            660                 665                 670         


Ile Ala Gly Pro Gln Gly Pro Lys Gly Asp Arg Gly Ser Arg Gly Glu 
        675                 680                 685             


Lys Gly Asp Pro Gly Lys Asp Gly Val Gly Gln Pro Gly Leu Pro Gly 
    690                 695                 700                 


Pro Pro Gly Pro Pro Gly Pro Val Val Tyr Val Ser Glu Gln Asp Gly 
705                 710                 715                 720 


Ser Val Leu Ser Val Pro Gly Pro Glu Gly Arg Pro Gly Phe Ala Gly 
                725                 730                 735     


Phe Pro Gly Pro Ala Gly Pro Lys Gly Asn Leu Gly Ser Lys Gly Glu 
            740                 745                 750         


Arg Gly Ser Pro Gly Pro Lys Gly Glu Lys Gly Glu Pro Gly Ser Ile 
        755                 760                 765             


Phe Ser Pro Asp Gly Gly Ala Leu Gly Pro Ala Gln Lys Gly Ala Lys 
    770                 775                 780                 


Gly Glu Pro Gly Phe Arg Gly Pro Pro Gly Pro Tyr Gly Arg Pro Gly 
785                 790                 795                 800 


Tyr Lys Gly Glu Ile Gly Phe Pro Gly Arg Pro Gly Arg Pro Gly Met 
                805                 810                 815     


Asn Gly Leu Lys Gly Glu Lys Gly Glu Pro Gly Asp Ala Ser Leu Gly 
            820                 825                 830         


Phe Gly Met Arg Gly Met Pro Gly Pro Pro Gly Pro Pro Gly Pro Pro 
        835                 840                 845             


Gly Pro Pro Gly Thr Pro Val Tyr Asp Ser Asn Val Phe Ala Glu Ser 
    850                 855                 860                 


Ser Arg Pro Gly Pro Pro Gly Leu Pro Gly Asn Gln Gly Pro Pro Gly 
865                 870                 875                 880 


Pro Lys Gly Ala Lys Gly Glu Val Gly Pro Pro Gly Pro Pro Gly Gln 
                885                 890                 895     


Phe Pro Phe Asp Phe Leu Gln Leu Glu Ala Glu Met Lys Gly Glu Lys 
            900                 905                 910         


Gly Asp Arg Gly Asp Ala Gly Gln Lys Gly Glu Arg Gly Glu Pro Gly 
        915                 920                 925             


Gly Gly Gly Phe Phe Gly Ser Ser Leu Pro Gly Pro Pro Gly Pro Pro 
    930                 935                 940                 


Gly Pro Arg Gly Tyr Pro Gly Ile Pro Gly Pro Lys Gly Glu Ser Ile 
945                 950                 955                 960 


Arg Gly Gln Pro Gly Pro Pro Gly Pro Gln Gly Pro Pro Gly Ile Gly 
                965                 970                 975     


Tyr Glu Gly Arg Gln Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly Pro 
            980                 985                 990         


Pro Ser Phe Pro Gly Pro His Arg  Gln Thr Ile Ser Val  Pro Gly Pro 
        995                 1000                 1005             


Pro Gly  Pro Pro Gly Pro Pro  Gly Pro Pro Gly Thr  Met Gly Ala 
    1010                 1015                 1020             


Ser Ser  Gly Val Arg Leu Trp  Ala Thr Arg Gln Ala  Met Leu Gly 
    1025                 1030                 1035             


Gln Val  His Glu Val Pro Glu  Gly Trp Leu Ile Phe  Val Ala Glu 
    1040                 1045                 1050             


Gln Glu  Glu Leu Tyr Val Arg  Val Gln Asn Gly Phe  Arg Lys Val 
    1055                 1060                 1065             


Gln Leu  Glu Ala Arg Thr Pro  Leu Pro Arg Gly Thr  Asp Asn Glu 
    1070                 1075                 1080             


Val Ala  Ala Leu Gln Pro Pro  Val Val Gln Leu His  Asp Ser Asn 
    1085                 1090                 1095             


Pro Tyr  Pro Arg Arg Glu His  Pro His Pro Thr Ala  Arg Pro Trp 
    1100                 1105                 1110             


Arg Ala  Asp Asp Ile Leu Ala  Ser Pro Pro Arg Leu  Pro Glu Pro 
    1115                 1120                 1125             


Gln Pro  Tyr Pro Gly Ala Pro  His His Ser Ser Tyr  Val His Leu 
    1130                 1135                 1140             


Arg Pro  Ala Arg Pro Thr Ser  Pro Pro Ala His Ser  His Arg Asp 
    1145                 1150                 1155             


Phe Gln  Pro Val Leu His Leu  Val Ala Leu Asn Ser  Pro Leu Ser 
    1160                 1165                 1170             


Gly Gly  Met Arg Gly Ile Arg  Gly Ala Asp Phe Gln  Cys Phe Gln 
    1175                 1180                 1185             


Gln Ala  Arg Ala Val Gly Leu  Ala Gly Thr Phe Arg  Ala Phe Leu 
    1190                 1195                 1200             


Ser Ser  Arg Leu Gln Asp Leu  Tyr Ser Ile Val Arg  Arg Ala Asp 
    1205                 1210                 1215             


Arg Ala  Ala Val Pro Ile Val  Asn Leu Lys Asp Glu  Leu Leu Phe 
    1220                 1225                 1230             


Pro Ser  Trp Glu Ala Leu Phe  Ser Gly Ser Glu Gly  Pro Leu Lys 
    1235                 1240                 1245             


Pro Gly  Ala Arg Ile Phe Ser  Phe Asp Gly Lys Asp  Val Leu Arg 
    1250                 1255                 1260             


His Pro  Thr Trp Pro Gln Lys  Ser Val Trp His Gly  Ser Asp Pro 
    1265                 1270                 1275             


Asn Gly  Arg Arg Leu Thr Glu  Ser Tyr Cys Glu Thr  Trp Arg Thr 
    1280                 1285                 1290             


Glu Ala  Pro Ser Ala Thr Gly  Gln Ala Ser Ser Leu  Leu Gly Gly 
    1295                 1300                 1305             


Arg Leu  Leu Gly Gln Ser Ala  Ala Ser Cys His His  Ala Tyr Ile 
    1310                 1315                 1320             


Val Leu  Cys Ile Glu Asn Ser  Phe Met Thr Ala Ser  Lys 
    1325                 1330                 1335     


<210>  4265
<211>  167
<212>  PRT
<213>  homo sapiens

<400>  4265

Met Ser Leu Ala Leu Arg Ser Glu Leu Val Val Asp Lys Thr Lys Arg 
1               5                   10                  15      


Lys Lys Arg Arg Glu Leu Ser Glu Glu Gln Lys Gln Glu Ile Lys Asp 
            20                  25                  30          


Ala Phe Glu Leu Phe Asp Thr Asp Lys Asp Glu Ala Ile Asp Tyr His 
        35                  40                  45              


Glu Leu Lys Val Ala Met Arg Ala Leu Gly Phe Asp Val Lys Lys Ala 
    50                  55                  60                  


Asp Val Leu Lys Ile Leu Lys Asp Tyr Asp Arg Glu Ala Thr Gly Lys 
65                  70                  75                  80  


Ile Thr Phe Glu Asp Phe Asn Glu Val Val Thr Asp Trp Ile Leu Glu 
                85                  90                  95      


Arg Asp Pro His Glu Glu Ile Leu Lys Ala Phe Lys Leu Phe Asp Asp 
            100                 105                 110         


Asp Asp Ser Gly Lys Ile Ser Leu Arg Asn Leu Arg Arg Val Ala Arg 
        115                 120                 125             


Glu Leu Gly Glu Asn Met Ser Asp Glu Glu Leu Arg Ala Met Ile Glu 
    130                 135                 140                 


Glu Phe Asp Lys Asp Gly Asp Gly Glu Ile Asn Gln Glu Glu Phe Ile 
145                 150                 155                 160 


Ala Ile Met Thr Gly Asp Ile 
                165         


<210>  4266
<211>  552
<212>  PRT
<213>  homo sapiens

<400>  4266

Met Glu Thr Ser Arg Ser Arg Gly Gly Gly Gly Ala Val Ser Glu Arg 
1               5                   10                  15      


Gly Gly Ala Gly Ala Ser Val Gly Val Cys Arg Arg Lys Ala Glu Ala 
            20                  25                  30          


Gly Ala Gly Thr Gly Thr Leu Ala Ala Asp Met Asp Leu His Cys Asp 
        35                  40                  45              


Cys Ala Ala Glu Thr Pro Ala Ala Glu Pro Pro Ser Gly Lys Ile Asn 
    50                  55                  60                  


Lys Ala Ala Phe Lys Leu Phe Lys Lys Arg Lys Ser Gly Gly Thr Met 
65                  70                  75                  80  


Pro Ser Ile Phe Gly Val Lys Asn Lys Gly Asp Gly Lys Ser Ser Gly 
                85                  90                  95      


Pro Thr Gly Leu Val Arg Ser Arg Thr His Asp Gly Leu Ala Glu Val 
            100                 105                 110         


Leu Val Leu Glu Ser Gly Arg Lys Glu Glu Pro Arg Gly Gly Gly Asp 
        115                 120                 125             


Ser Gly Gly Gly Gly Gly Gly Arg Pro Asn Pro Gly Pro Pro Arg Ala 
    130                 135                 140                 


Ala Gly Pro Gly Gly Gly Ser Leu Ala Ser Ser Ser Val Ala Lys Ser 
145                 150                 155                 160 


His Ser Phe Phe Ser Leu Leu Lys Lys Asn Gly Arg Ser Glu Asn Gly 
                165                 170                 175     


Lys Gly Glu Pro Val Asp Ala Ser Lys Ala Gly Gly Lys Gln Lys Arg 
            180                 185                 190         


Gly Leu Arg Gly Leu Phe Ser Gly Met Arg Trp His Arg Lys Asp Lys 
        195                 200                 205             


Arg Ala Lys Ala Glu Ala Ala Glu Gly Arg Ala Pro Gly Gly Gly Leu 
    210                 215                 220                 


Ile Leu Pro Gly Ser Leu Thr Ala Ser Leu Glu Cys Val Lys Glu Glu 
225                 230                 235                 240 


Thr Pro Arg Ala Ala Arg Glu Pro Glu Glu Pro Ser Gln Asp Ala Pro 
                245                 250                 255     


Arg Asp Pro Ala Gly Cys Gly Asp Ile Ile Ala Asp Gln Glu Glu Glu 
            260                 265                 270         


Ala Gly Pro Ser Cys Asp Lys His Val Pro Gly Pro Gly Lys Pro Ala 
        275                 280                 285             


Leu Ser Lys Lys Asn Pro Gly Val Val Ala Tyr Gln Gly Gly Gly Glu 
    290                 295                 300                 


Glu Met Ala Ser Pro Asp Glu Val Asp Asp Thr Tyr Leu Gln Glu Phe 
305                 310                 315                 320 


Trp Asp Met Leu Ser Gln Thr Glu Glu Gln Gly Pro Glu Pro Gln Glu 
                325                 330                 335     


Gly Ala Ala Lys Val Ala Ala Ala Leu Glu Thr Lys Val Val Pro Glu 
            340                 345                 350         


Thr Pro Lys Asp Thr Arg Cys Val Glu Ala Ala Lys Asp Ala Ser Ser 
        355                 360                 365             


Val Lys Arg Arg Arg Leu Asn Arg Ile Pro Ile Glu Pro His Pro Lys 
    370                 375                 380                 


Glu Glu Pro Lys His Pro Glu Lys Glu Gln Gln Glu Gly Val Pro Asn 
385                 390                 395                 400 


Ser Asp Glu Gly Tyr Trp Asp Ser Thr Thr Pro Gly Pro Glu Glu Asp 
                405                 410                 415     


Ser Ser Ser Ser Gly Lys Lys Ala Gly Ile Pro Arg Asp Ser Tyr Ser 
            420                 425                 430         


Gly Asp Ala Leu Tyr Asp Leu Tyr Ala Asp Pro Asp Gly Ser Pro Ala 
        435                 440                 445             


Thr Leu Pro Gly Gly Lys Asp Asn Glu Glu Thr Ser Ser Leu Ser Arg 
    450                 455                 460                 


Leu Lys Pro Val Ser Pro Gly Thr Ile Thr Cys Pro Leu Arg Thr Pro 
465                 470                 475                 480 


Gly Ser Leu Leu Lys Asp Ser Lys Ile Pro Ile Ser Ile Lys His Leu 
                485                 490                 495     


Thr Asn Leu Pro Ser Ser His Pro Val Val His Gln Gln Pro Ser Arg 
            500                 505                 510         


Ser Glu Met Pro Arg Thr Lys Ile Pro Val Ser Lys Val Leu Val Arg 
        515                 520                 525             


Arg Val Ser Asn Arg Gly Leu Ala Gly Thr Thr Ile Arg Ala Thr Ala 
    530                 535                 540                 


Cys His Asp Ser Ala Lys Lys Leu 
545                 550         


<210>  4267
<211>  109
<212>  PRT
<213>  homo sapiens

<400>  4267

Met Glu Asp Tyr Thr Lys Ile Glu Lys Ile Gly Glu Gly Thr Tyr Gly 
1               5                   10                  15      


Val Val Tyr Lys Gly Arg His Lys Thr Thr Gly Gln Val Val Ala Met 
            20                  25                  30          


Lys Lys Ile Arg Leu Glu Ser Glu Glu Glu Gly Val Pro Ser Thr Ala 
        35                  40                  45              


Ile Arg Glu Ile Ser Leu Leu Lys Glu Leu Arg His Pro Asn Ile Val 
    50                  55                  60                  


Ser Leu Gln Asp Val Leu Met Gln Asp Ser Arg Leu Tyr Leu Ile Phe 
65                  70                  75                  80  


Glu Phe Leu Ser Met Asp Leu Lys Lys Tyr Leu Asp Ser Ile Pro Pro 
                85                  90                  95      


Gly Gln Tyr Met Asp Ser Ser Leu Val Lys Val Lys Ala 
            100                 105                 


<210>  4268
<211>  1486
<212>  PRT
<213>  homo sapiens

<400>  4268

Met Ser Leu Thr Ser Trp Phe Leu Val Ser Ser Gly Gly Thr Arg His 
1               5                   10                  15      


Arg Leu Pro Arg Glu Met Ile Phe Val Gly Arg Asp Asp Cys Glu Leu 
            20                  25                  30          


Met Leu Gln Ser Arg Ser Val Asp Lys Gln His Ala Val Ile Asn Tyr 
        35                  40                  45              


Asp Ala Ser Thr Asp Glu His Leu Val Lys Asp Leu Gly Ser Leu Asn 
    50                  55                  60                  


Gly Thr Phe Val Asn Asp Val Arg Ile Pro Glu Gln Thr Tyr Ile Thr 
65                  70                  75                  80  


Leu Lys Leu Glu Asp Lys Leu Arg Phe Gly Tyr Asp Thr Asn Leu Phe 
                85                  90                  95      


Thr Val Val Gln Gly Glu Met Arg Val Pro Glu Glu Ala Leu Lys His 
            100                 105                 110         


Glu Lys Phe Thr Ile Gln Leu Gln Leu Ser Gln Lys Ser Ser Glu Ser 
        115                 120                 125             


Glu Leu Ser Lys Ser Ala Ser Ala Lys Ser Ile Asp Ser Lys Val Ala 
    130                 135                 140                 


Asp Ala Ala Thr Glu Val Gln His Lys Thr Thr Glu Ala Leu Lys Ser 
145                 150                 155                 160 


Glu Glu Lys Ala Met Asp Ile Ser Ala Met Pro Arg Gly Thr Pro Leu 
                165                 170                 175     


Tyr Gly Gln Pro Ser Trp Trp Gly Asp Asp Glu Val Asp Glu Lys Arg 
            180                 185                 190         


Ala Phe Lys Thr Asn Gly Lys Pro Glu Glu Lys Asn His Glu Ala Gly 
        195                 200                 205             


Thr Ser Gly Cys Gly Ile Asp Ala Lys Gln Val Glu Glu Gln Ser Ala 
    210                 215                 220                 


Ala Ala Asn Glu Glu Val Leu Phe Pro Phe Cys Arg Glu Pro Ser Tyr 
225                 230                 235                 240 


Phe Glu Ile Pro Thr Lys Glu Phe Gln Gln Pro Ser Gln Ile Thr Glu 
                245                 250                 255     


Ser Thr Ile His Glu Ile Pro Thr Lys Asp Thr Pro Ser Ser His Ile 
            260                 265                 270         


Thr Gly Ala Gly His Ala Ser Phe Thr Ile Glu Phe Asp Asp Ser Thr 
        275                 280                 285             


Pro Gly Lys Val Thr Ile Arg Asp His Val Thr Lys Phe Thr Ser Asp 
    290                 295                 300                 


Gln Arg His Lys Ser Lys Lys Ser Ser Pro Gly Thr Gln Asp Leu Leu 
305                 310                 315                 320 


Gly Ile Gln Thr Gly Met Met Ala Pro Glu Asn Lys Val Ala Asp Trp 
                325                 330                 335     


Leu Ala Gln Asn Asn Pro Pro Gln Met Leu Trp Glu Arg Thr Glu Glu 
            340                 345                 350         


Asp Ser Lys Ser Ile Lys Ser Asp Val Pro Val Tyr Leu Lys Arg Leu 
        355                 360                 365             


Lys Gly Asn Lys His Asp Asp Gly Thr Gln Ser Asp Ser Glu Asn Ala 
    370                 375                 380                 


Gly Ala His Arg Arg Cys Ser Lys Arg Ala Thr Leu Glu Glu His Leu 
385                 390                 395                 400 


Arg Arg His His Ser Glu His Lys Lys Leu Gln Lys Val Gln Ala Thr 
                405                 410                 415     


Glu Lys His Gln Asp Gln Ala Val Val Phe Gly Val Asp Asp Asn Gln 
            420                 425                 430         


Asp Tyr Asn Arg Pro Val Ile Asn Glu Lys His Lys Asp Leu Ile Lys 
        435                 440                 445             


Asp Trp Ala Leu Ser Ser Ala Ala Ala Val Met Glu Glu Arg Lys Pro 
    450                 455                 460                 


Leu Thr Thr Ser Gly Phe His His Ser Glu Glu Gly Thr Ser Ser Ser 
465                 470                 475                 480 


Gly Ser Lys Arg Trp Val Ser Gln Trp Ala Ser Leu Ala Ala Asn His 
                485                 490                 495     


Thr Arg His Asp Gln Glu Glu Arg Ile Met Glu Phe Ser Ala Pro Leu 
            500                 505                 510         


Pro Leu Glu Asn Glu Thr Glu Ile Ser Glu Ser Gly Met Thr Val Arg 
        515                 520                 525             


Ser Thr Gly Ser Ala Thr Ser Leu Ala Ser Gln Gly Glu Arg Arg Arg 
    530                 535                 540                 


Arg Thr Leu Pro Gln Leu Pro Asn Glu Glu Lys Ser Leu Glu Ser His 
545                 550                 555                 560 


Arg Ala Lys Val Val Thr Gln Arg Ser Glu Ile Gly Glu Lys Gln Asp 
                565                 570                 575     


Thr Glu Leu Gln Glu Lys Glu Thr Pro Thr Gln Val Tyr Gln Lys Asp 
            580                 585                 590         


Lys Gln Asp Ala Asp Arg Pro Leu Ser Lys Met Asn Arg Ala Val Asn 
        595                 600                 605             


Gly Glu Thr Leu Lys Thr Gly Gly Asp Asn Lys Thr Leu Leu His Leu 
    610                 615                 620                 


Gly Ser Ser Ala Pro Gly Lys Glu Lys Ser Glu Thr Asp Lys Glu Thr 
625                 630                 635                 640 


Ser Leu Val Lys Gln Thr Leu Ala Lys Leu Gln Gln Gln Glu Gln Arg 
                645                 650                 655     


Glu Glu Ala Gln Trp Thr Pro Thr Lys Leu Ser Ser Lys Asn Val Ser 
            660                 665                 670         


Gly Gln Thr Asp Lys Cys Arg Glu Glu Thr Phe Lys Gln Glu Ser Gln 
        675                 680                 685             


Pro Pro Glu Lys Asn Ser Gly His Ser Thr Ser Lys Gly Asp Arg Val 
    690                 695                 700                 


Ala Gln Ser Glu Ser Lys Arg Arg Lys Ala Glu Glu Ile Leu Lys Ser 
705                 710                 715                 720 


Gln Thr Pro Lys Gly Gly Asp Lys Lys Glu Ser Ser Lys Ser Leu Val 
                725                 730                 735     


Arg Gln Gly Ser Phe Thr Ile Glu Lys Pro Ser Pro Asn Ile Pro Ile 
            740                 745                 750         


Glu Leu Ile Pro His Ile Asn Lys Gln Thr Ser Ser Thr Pro Ser Ser 
        755                 760                 765             


Leu Ala Leu Thr Ser Ala Ser Arg Ile Arg Glu Arg Ser Glu Ser Leu 
    770                 775                 780                 


Asp Pro Asp Ser Ser Met Asp Thr Thr Leu Ile Leu Lys Asp Thr Glu 
785                 790                 795                 800 


Ala Val Met Ala Phe Leu Glu Ala Lys Leu Arg Glu Asp Asn Lys Thr 
                805                 810                 815     


Asp Glu Gly Pro Asp Thr Pro Ser Tyr Asn Arg Asp Asn Ser Ile Ser 
            820                 825                 830         


Pro Glu Ser Asp Val Asp Thr Ala Ser Thr Ile Ser Leu Val Thr Gly 
        835                 840                 845             


Glu Thr Glu Arg Lys Ser Thr Gln Lys Arg Lys Ser Phe Thr Ser Leu 
    850                 855                 860                 


Tyr Lys Asp Arg Cys Ser Thr Gly Ser Pro Ser Lys Asp Val Thr Lys 
865                 870                 875                 880 


Ser Ser Ser Ser Gly Ala Arg Glu Lys Met Glu Lys Lys Thr Lys Ser 
                885                 890                 895     


Arg Ser Thr Asp Val Gly Ser Arg Ala Asp Gly Arg Lys Phe Val Gln 
            900                 905                 910         


Ser Ser Gly Arg Ile Arg Gln Pro Ser Val Asp Leu Thr Asp Asp Asp 
        915                 920                 925             


Gln Thr Ser Ser Val Pro His Ser Ala Ile Ser Asp Ile Met Ser Ser 
    930                 935                 940                 


Asp Gln Glu Thr Tyr Ser Cys Lys Pro His Gly Arg Thr Pro Leu Thr 
945                 950                 955                 960 


Ser Ala Asp Glu His Val His Ser Lys Leu Glu Gly Ser Lys Val Thr 
                965                 970                 975     


Lys Ser Lys Thr Ser Pro Val Val Ser Gly Ser Ser Ser Lys Ser Thr 
            980                 985                 990         


Thr Leu Pro Arg Pro Arg Pro Thr  Arg Thr Ser Leu Leu  Arg Arg Ala 
        995                 1000                 1005             


Arg Leu  Gly Glu Ala Ser Asp  Ser Glu Leu Ala Asp  Ala Asp Lys 
    1010                 1015                 1020             


Ala Ser  Val Ala Ser Glu Val  Ser Thr Thr Ser Ser  Thr Ser Lys 
    1025                 1030                 1035             


Pro Pro  Thr Gly Arg Arg Asn  Ile Ser Arg Ile Asp  Leu Leu Ala 
    1040                 1045                 1050             


Gln Pro  Arg Arg Thr Arg Leu  Gly Ser Leu Ser Ala  Arg Ser Asp 
    1055                 1060                 1065             


Ser Glu  Ala Thr Ile Ser Arg  Ser Ser Ala Ser Ser  Arg Thr Ala 
    1070                 1075                 1080             


Glu Ala  Ile Ile Arg Ser Gly  Ala Arg Leu Val Pro  Ser Asp Lys 
    1085                 1090                 1095             


Phe Ser  Pro Arg Ile Arg Ala  Asn Ser Ile Ser Arg  Leu Ser Asp 
    1100                 1105                 1110             


Ser Lys  Val Lys Ser Met Thr  Ser Ala His Gly Ser  Ala Ser Val 
    1115                 1120                 1125             


Asn Ser  Arg Trp Arg Arg Phe  Pro Thr Asp Tyr Ala  Ser Thr Ser 
    1130                 1135                 1140             


Glu Asp  Glu Phe Gly Ser Asn  Arg Asn Ser Pro Lys  His Thr Arg 
    1145                 1150                 1155             


Leu Arg  Thr Ser Pro Ala Leu  Lys Thr Thr Arg Leu  Gln Ser Ala 
    1160                 1165                 1170             


Gly Ser  Ala Met Pro Thr Ser  Ser Ser Phe Lys His  Arg Ile Lys 
    1175                 1180                 1185             


Glu Gln  Glu Asp Tyr Ile Arg  Asp Trp Thr Ala His  Arg Glu Glu 
    1190                 1195                 1200             


Ile Ala  Arg Ile Ser Gln Asp  Leu Ala Leu Ile Ala  Arg Glu Ile 
    1205                 1210                 1215             


Asn Asp  Val Ala Gly Glu Ile  Asp Ser Val Thr Ser  Ser Gly Thr 
    1220                 1225                 1230             


Ala Pro  Ser Thr Thr Val Ser  Thr Ala Ala Thr Thr  Pro Gly Ser 
    1235                 1240                 1245             


Ala Ile  Asp Thr Arg Glu Glu  Leu Val Asp Arg Val  Phe Asp Glu 
    1250                 1255                 1260             


Ser Leu  Asn Phe Arg Lys Ile  Pro Pro Leu Val His  Ser Lys Thr 
    1265                 1270                 1275             


Pro Glu  Gly Asn Asn Gly Arg  Ser Gly Asp Pro Arg  Pro Gln Ala 
    1280                 1285                 1290             


Ala Glu  Pro Pro Asp His Leu  Thr Ile Thr Arg Arg  Arg Thr Trp 
    1295                 1300                 1305             


Ser Arg  Asp Glu Val Met Gly  Asp Asn Leu Leu Leu  Ser Ser Val 
    1310                 1315                 1320             


Phe Gln  Phe Ser Lys Lys Ile  Arg Gln Ser Ile Asp  Lys Thr Ala 
    1325                 1330                 1335             


Gly Lys  Ile Arg Ile Leu Phe  Lys Asp Lys Asp Arg  Asn Trp Asp 
    1340                 1345                 1350             


Asp Ile  Glu Ser Lys Leu Arg  Ala Glu Ser Glu Val  Pro Ile Val 
    1355                 1360                 1365             


Lys Thr  Ser Ser Met Glu Ile  Ser Ser Ile Leu Gln  Glu Leu Lys 
    1370                 1375                 1380             


Arg Val  Glu Lys Gln Leu Gln  Ala Ile Asn Ala Met  Ile Asp Pro 
    1385                 1390                 1395             


Asp Gly  Thr Leu Glu Ala Leu  Asn Asn Met Gly Phe  Pro Ser Ala 
    1400                 1405                 1410             


Met Leu  Pro Ser Pro Pro Lys  Gln Lys Ser Ser Pro  Val Asn Asn 
    1415                 1420                 1425             


His His  Ser Pro Gly Gln Thr  Pro Thr Leu Gly Gln  Pro Glu Ala 
    1430                 1435                 1440             


Arg Ala  Leu His Pro Ala Ala  Val Ser Ala Ala Ala  Glu Phe Glu 
    1445                 1450                 1455             


Asn Ala  Glu Ser Glu Ala Asp  Phe Ser Ile His Phe  Asn Arg Phe 
    1460                 1465                 1470             


Asn Pro  Asp Gly Glu Glu Glu  Asp Val Thr Val Gln  Glu 
    1475                 1480                 1485     


<210>  4269
<211>  497
<212>  PRT
<213>  homo sapiens

<400>  4269

Met Gly Arg Lys Lys Ile Gln Ile Thr Arg Ile Met Asp Glu Arg Asn 
1               5                   10                  15      


Arg Gln Val Thr Phe Thr Lys Arg Lys Phe Gly Leu Met Lys Lys Ala 
            20                  25                  30          


Tyr Glu Leu Ser Val Leu Cys Asp Cys Glu Ile Ala Leu Ile Ile Phe 
        35                  40                  45              


Asn Ser Ser Asn Lys Leu Phe Gln Tyr Ala Ser Thr Asp Met Asp Lys 
    50                  55                  60                  


Val Leu Leu Lys Tyr Thr Glu Tyr Asn Glu Pro His Glu Ser Arg Thr 
65                  70                  75                  80  


Asn Ser Asp Ile Val Glu Thr Leu Arg Lys Lys Gly Leu Asn Gly Cys 
                85                  90                  95      


Glu Ser Pro Asp Ala Asp Asp Tyr Phe Glu His Ser Pro Leu Ser Glu 
            100                 105                 110         


Asp Arg Phe Ser Lys Leu Asn Glu Asp Ser Asp Phe Ile Phe Lys Arg 
        115                 120                 125             


Gly Pro Pro Gly Leu Pro Pro Gln Asn Phe Ser Met Ser Val Thr Val 
    130                 135                 140                 


Pro Val Thr Ser Pro Asn Ala Leu Ser Tyr Thr Asn Pro Gly Ser Ser 
145                 150                 155                 160 


Leu Val Ser Pro Ser Leu Ala Ala Ser Ser Thr Leu Thr Asp Ser Ser 
                165                 170                 175     


Met Leu Ser Pro Pro Gln Thr Thr Leu His Arg Asn Val Ser Pro Gly 
            180                 185                 190         


Ala Pro Gln Arg Pro Pro Ser Thr Gly Asn Ala Gly Gly Met Leu Ser 
        195                 200                 205             


Thr Thr Asp Leu Thr Val Pro Asn Gly Ala Gly Ser Ser Pro Val Gly 
    210                 215                 220                 


Asn Gly Phe Val Asn Ser Arg Ala Ser Pro Asn Leu Ile Gly Ala Thr 
225                 230                 235                 240 


Gly Ala Asn Ser Leu Gly Lys Val Met Pro Thr Lys Ser Pro Pro Pro 
                245                 250                 255     


Pro Gly Gly Gly Asn Leu Gly Met Asn Ser Arg Lys Pro Asp Leu Arg 
            260                 265                 270         


Val Val Ile Pro Pro Ser Ser Lys Gly Met Met Pro Pro Leu Asn Thr 
        275                 280                 285             


Gln Arg Ile Ser Ser Ser Gln Ala Thr Gln Pro Leu Ala Thr Pro Val 
    290                 295                 300                 


Val Ser Val Thr Thr Pro Ser Leu Pro Pro Gln Gly Leu Val Tyr Ser 
305                 310                 315                 320 


Ala Met Pro Thr Ala Tyr Asn Thr Asp Tyr Ser Leu Thr Ser Ala Asp 
                325                 330                 335     


Leu Ser Ala Leu Gln Gly Phe Asn Ser Pro Gly Met Leu Ser Leu Gly 
            340                 345                 350         


Gln Val Ser Ala Trp Gln Gln His His Leu Gly Gln Ala Ala Leu Ser 
        355                 360                 365             


Ser Leu Val Ala Gly Gly Gln Leu Ser Gln Gly Ser Asn Leu Ser Ile 
    370                 375                 380                 


Asn Thr Asn Gln Asn Ile Ser Ile Lys Ser Glu Pro Ile Ser Pro Pro 
385                 390                 395                 400 


Arg Asp Arg Met Thr Pro Ser Gly Phe Gln Gln Gln Gln Gln Gln Gln 
                405                 410                 415     


Gln Gln Gln Gln Pro Pro Pro Pro Pro Gln Pro Gln Pro Gln Pro Pro 
            420                 425                 430         


Gln Pro Gln Pro Arg Gln Glu Met Gly Arg Ser Pro Val Asp Ser Leu 
        435                 440                 445             


Ser Ser Ser Ser Ser Ser Tyr Asp Gly Ser Asp Arg Glu Asp Pro Arg 
    450                 455                 460                 


Gly Asp Phe His Ser Pro Ile Val Leu Gly Arg Pro Pro Asn Thr Glu 
465                 470                 475                 480 


Asp Arg Glu Ser Pro Ser Val Lys Arg Met Arg Met Asp Ala Trp Val 
                485                 490                 495     


Thr 
    


<210>  4270
<211>  708
<212>  PRT
<213>  homo sapiens

<400>  4270

Met Lys Asp Met Pro Leu Arg Ile His Val Leu Leu Gly Leu Ala Ile 
1               5                   10                  15      


Thr Thr Leu Val Gln Ala Val Asp Lys Lys Val Asp Cys Pro Arg Leu 
            20                  25                  30          


Cys Thr Cys Glu Ile Arg Pro Trp Phe Thr Pro Arg Ser Ile Tyr Met 
        35                  40                  45              


Glu Ala Ser Thr Val Asp Cys Asn Asp Leu Gly Leu Leu Thr Phe Pro 
    50                  55                  60                  


Ala Arg Leu Pro Ala Asn Thr Gln Ile Leu Leu Leu Gln Thr Asn Asn 
65                  70                  75                  80  


Ile Ala Lys Ile Glu Tyr Ser Thr Asp Phe Pro Val Asn Leu Thr Gly 
                85                  90                  95      


Leu Asp Leu Ser Gln Asn Asn Leu Ser Ser Val Thr Asn Ile Asn Val 
            100                 105                 110         


Lys Lys Met Pro Gln Leu Leu Ser Val Tyr Leu Glu Glu Asn Lys Leu 
        115                 120                 125             


Thr Glu Leu Pro Glu Lys Cys Leu Ser Glu Leu Ser Asn Leu Gln Glu 
    130                 135                 140                 


Leu Tyr Ile Asn His Asn Leu Leu Ser Thr Ile Ser Pro Gly Ala Phe 
145                 150                 155                 160 


Ile Gly Leu His Asn Leu Leu Arg Leu His Leu Asn Ser Asn Arg Leu 
                165                 170                 175     


Gln Met Ile Asn Ser Lys Trp Phe Asp Ala Leu Pro Asn Leu Glu Ile 
            180                 185                 190         


Leu Met Ile Gly Glu Asn Pro Ile Ile Arg Ile Lys Asp Met Asn Phe 
        195                 200                 205             


Lys Pro Leu Ile Asn Leu Arg Ser Leu Val Ile Ala Gly Ile Asn Leu 
    210                 215                 220                 


Thr Glu Ile Pro Asp Asn Ala Leu Val Gly Leu Glu Asn Leu Glu Ser 
225                 230                 235                 240 


Ile Ser Phe Tyr Asp Asn Arg Leu Ile Lys Val Pro His Val Ala Leu 
                245                 250                 255     


Gln Lys Val Val Asn Leu Lys Phe Leu Asp Leu Asn Lys Asn Pro Ile 
            260                 265                 270         


Asn Arg Ile Arg Arg Gly Asp Phe Ser Asn Met Leu His Leu Lys Glu 
        275                 280                 285             


Leu Gly Ile Asn Asn Met Pro Glu Leu Ile Ser Ile Asp Ser Leu Ala 
    290                 295                 300                 


Val Asp Asn Leu Pro Asp Leu Arg Lys Ile Glu Ala Thr Asn Asn Pro 
305                 310                 315                 320 


Arg Leu Ser Tyr Ile His Pro Asn Ala Phe Phe Arg Leu Pro Lys Leu 
                325                 330                 335     


Glu Ser Leu Met Leu Asn Ser Asn Ala Leu Ser Ala Leu Tyr His Gly 
            340                 345                 350         


Thr Ile Glu Ser Leu Pro Asn Leu Lys Glu Ile Ser Ile His Ser Asn 
        355                 360                 365             


Pro Ile Arg Cys Asp Cys Val Ile Arg Trp Met Asn Met Asn Lys Thr 
    370                 375                 380                 


Asn Ile Arg Phe Met Glu Pro Asp Ser Leu Phe Cys Val Asp Pro Pro 
385                 390                 395                 400 


Glu Phe Gln Gly Gln Asn Val Arg Gln Val His Phe Arg Asp Met Met 
                405                 410                 415     


Glu Ile Cys Leu Pro Leu Ile Ala Pro Glu Ser Phe Pro Ser Asn Leu 
            420                 425                 430         


Asn Val Glu Ala Gly Ser Tyr Val Ser Phe His Cys Arg Ala Thr Ala 
        435                 440                 445             


Glu Pro Gln Pro Glu Ile Tyr Trp Ile Thr Pro Ser Gly Gln Lys Leu 
    450                 455                 460                 


Leu Pro Asn Thr Leu Thr Asp Lys Phe Tyr Val His Ser Glu Gly Thr 
465                 470                 475                 480 


Leu Asp Ile Asn Gly Val Thr Pro Lys Glu Gly Gly Leu Tyr Thr Cys 
                485                 490                 495     


Ile Ala Thr Asn Leu Val Gly Ala Asp Leu Lys Ser Val Met Ile Lys 
            500                 505                 510         


Val Asp Gly Ser Phe Pro Gln Asp Asn Asn Gly Ser Leu Asn Ile Lys 
        515                 520                 525             


Ile Arg Asp Ile Gln Ala Asn Ser Val Leu Val Ser Trp Lys Ala Ser 
    530                 535                 540                 


Ser Lys Ile Leu Lys Ser Ser Val Lys Trp Thr Ala Phe Val Lys Thr 
545                 550                 555                 560 


Glu Asn Ser His Ala Ala Gln Ser Ala Arg Ile Pro Ser Asp Val Lys 
                565                 570                 575     


Val Tyr Asn Leu Thr His Leu Asn Pro Ser Thr Glu Tyr Lys Ile Cys 
            580                 585                 590         


Ile Asp Ile Pro Thr Ile Tyr Gln Lys Asn Arg Lys Lys Cys Val Asn 
        595                 600                 605             


Val Thr Thr Lys Gly Leu His Pro Asp Gln Lys Glu Tyr Glu Lys Asn 
    610                 615                 620                 


Asn Thr Thr Thr Leu Met Ala Cys Leu Gly Gly Leu Leu Gly Ile Ile 
625                 630                 635                 640 


Gly Val Ile Cys Leu Ile Ser Cys Leu Ser Pro Glu Met Asn Cys Asp 
                645                 650                 655     


Gly Gly His Ser Tyr Val Arg Asn Tyr Leu Gln Lys Pro Thr Phe Ala 
            660                 665                 670         


Leu Gly Glu Leu Tyr Pro Pro Leu Ile Asn Leu Trp Glu Ala Gly Lys 
        675                 680                 685             


Glu Lys Ser Thr Ser Leu Lys Val Lys Ala Thr Val Ile Gly Leu Pro 
    690                 695                 700                 


Thr Asn Met Ser 
705             


<210>  4271
<211>  80
<212>  PRT
<213>  homo sapiens

<400>  4271

Met Ser Leu Arg Lys Gln Thr Pro Ser Asp Phe Leu Lys Gln Ile Ile 
1               5                   10                  15      


Gly Arg Pro Val Val Val Lys Leu Asn Ser Gly Val Asp Tyr Arg Gly 
            20                  25                  30          


Val Leu Ala Cys Leu Asp Gly Tyr Met Asn Ile Ala Leu Glu Gln Thr 
        35                  40                  45              


Glu Glu Tyr Val Asn Gly Gln Leu Lys Asn Lys Tyr Gly Asp Ala Phe 
    50                  55                  60                  


Ile Arg Gly Asn Asn Val Leu Tyr Ile Ser Thr Gln Lys Arg Arg Met 
65                  70                  75                  80  


<210>  4272
<211>  1721
<212>  PRT
<213>  homo sapiens

<400>  4272

Met Ala Gly Ala Trp Leu Arg Trp Gly Leu Leu Leu Trp Ala Gly Leu 
1               5                   10                  15      


Leu Ala Ser Ser Ala His Gly Arg Leu Arg Arg Ile Thr Tyr Val Val 
            20                  25                  30          


His Pro Gly Pro Gly Leu Ala Ala Gly Ala Leu Pro Leu Ser Gly Pro 
        35                  40                  45              


Pro Arg Ser Arg Thr Phe Asn Val Ala Leu Asn Ala Arg Tyr Ser Arg 
    50                  55                  60                  


Ser Ser Ala Ala Ala Gly Ala Pro Ser Arg Ala Ser Pro Gly Val Pro 
65                  70                  75                  80  


Ser Glu Arg Thr Arg Arg Thr Ser Lys Pro Gly Gly Ala Ala Leu Gln 
                85                  90                  95      


Gly Leu Arg Pro Pro Pro Pro Pro Pro Pro Glu Pro Ala Arg Pro Ala 
            100                 105                 110         


Val Pro Gly Gly Gln Leu His Pro Asn Pro Gly Gly His Pro Ala Ala 
        115                 120                 125             


Ala Pro Phe Thr Lys Gln Gly Arg Gln Val Val Arg Ser Lys Val Pro 
    130                 135                 140                 


Gln Glu Thr Gln Ser Gly Gly Gly Ser Arg Leu Gln Val His Gln Lys 
145                 150                 155                 160 


Gln Gln Leu Gln Gly Val Asn Val Cys Gly Gly Arg Cys Cys His Gly 
                165                 170                 175     


Trp Ser Lys Ala Pro Gly Ser Gln Arg Cys Thr Lys Pro Ser Cys Val 
            180                 185                 190         


Pro Pro Cys Gln Asn Gly Gly Met Cys Leu Arg Pro Gln Leu Cys Val 
        195                 200                 205             


Cys Lys Pro Gly Thr Lys Gly Lys Ala Cys Glu Thr Ile Ala Ala Gln 
    210                 215                 220                 


Asp Thr Ser Ser Pro Val Phe Gly Gly Gln Ser Pro Gly Ala Ala Ser 
225                 230                 235                 240 


Ser Trp Gly Pro Pro Glu Gln Ala Ala Lys His Thr Ser Ser Lys Lys 
                245                 250                 255     


Ala Asp Thr Leu Pro Arg Val Ser Pro Val Ala Gln Met Thr Leu Thr 
            260                 265                 270         


Leu Lys Pro Lys Pro Ser Val Gly Leu Pro Gln Gln Ile His Ser Gln 
        275                 280                 285             


Val Thr Pro Leu Ser Ser Gln Ser Val Val Ile His His Gly Gln Thr 
    290                 295                 300                 


Gln Glu Tyr Val Leu Lys Pro Lys Tyr Phe Pro Ala Gln Lys Gly Ile 
305                 310                 315                 320 


Ser Gly Glu Gln Ser Thr Glu Gly Ser Phe Pro Leu Arg Tyr Val Gln 
                325                 330                 335     


Asp Gln Val Ala Ala Pro Phe Gln Leu Ser Asn His Thr Gly Arg Ile 
            340                 345                 350         


Lys Val Val Phe Thr Pro Ser Ile Cys Lys Val Thr Cys Thr Lys Gly 
        355                 360                 365             


Ser Cys Gln Asn Ser Cys Glu Lys Gly Asn Thr Thr Thr Leu Ile Ser 
    370                 375                 380                 


Glu Asn Gly His Ala Ala Asp Thr Leu Thr Ala Thr Asn Phe Arg Val 
385                 390                 395                 400 


Val Ile Cys His Leu Pro Cys Met Asn Gly Gly Gln Cys Ser Ser Arg 
                405                 410                 415     


Asp Lys Cys Gln Cys Pro Pro Asn Phe Thr Gly Lys Leu Cys Gln Ile 
            420                 425                 430         


Pro Val His Gly Ala Ser Val Pro Lys Leu Tyr Gln His Ser Gln Gln 
        435                 440                 445             


Pro Gly Lys Ala Leu Gly Thr His Val Ile His Ser Thr His Thr Leu 
    450                 455                 460                 


Pro Leu Thr Val Thr Ser Gln Gln Gly Val Lys Val Lys Phe Pro Pro 
465                 470                 475                 480 


Asn Ile Val Asn Ile His Val Lys His Pro Pro Glu Ala Ser Val Gln 
                485                 490                 495     


Ile His Gln Val Ser Arg Ile Asp Gly Pro Thr Gly Gln Lys Thr Lys 
            500                 505                 510         


Glu Ala Gln Pro Gly Gln Ser Gln Val Ser Tyr Gln Gly Leu Pro Val 
        515                 520                 525             


Gln Lys Thr Gln Thr Ile His Ser Thr Tyr Ser His Gln Gln Val Ile 
    530                 535                 540                 


Pro His Val Tyr Pro Val Ala Ala Lys Thr Gln Leu Gly Arg Cys Phe 
545                 550                 555                 560 


Gln Glu Thr Ile Gly Ser Gln Cys Gly Lys Ala Leu Pro Gly Leu Ser 
                565                 570                 575     


Lys Gln Glu Asp Cys Cys Gly Thr Val Gly Thr Ser Trp Gly Phe Asn 
            580                 585                 590         


Lys Cys Gln Lys Cys Pro Lys Lys Pro Ser Tyr His Gly Tyr Asn Gln 
        595                 600                 605             


Met Met Glu Cys Leu Pro Gly Tyr Lys Arg Val Asn Asn Thr Phe Cys 
    610                 615                 620                 


Gln Asp Ile Asn Glu Cys Gln Leu Gln Gly Val Cys Pro Asn Gly Glu 
625                 630                 635                 640 


Cys Leu Asn Thr Met Gly Ser Tyr Arg Cys Thr Cys Lys Ile Gly Phe 
                645                 650                 655     


Gly Pro Asp Pro Thr Phe Ser Ser Cys Val Pro Asp Pro Pro Val Ile 
            660                 665                 670         


Ser Glu Glu Lys Gly Pro Cys Tyr Arg Leu Val Ser Ser Gly Arg Gln 
        675                 680                 685             


Cys Met His Pro Leu Ser Val His Leu Thr Lys Gln Leu Cys Cys Cys 
    690                 695                 700                 


Ser Val Gly Lys Ala Trp Gly Pro His Cys Glu Lys Cys Pro Leu Pro 
705                 710                 715                 720 


Gly Thr Ala Ala Phe Lys Glu Ile Cys Pro Gly Gly Met Gly Tyr Thr 
                725                 730                 735     


Val Ser Gly Val His Arg Arg Arg Pro Ile His His His Val Gly Lys 
            740                 745                 750         


Gly Pro Val Phe Val Lys Pro Lys Asn Thr Gln Pro Val Ala Lys Ser 
        755                 760                 765             


Thr His Pro Pro Pro Leu Pro Ala Lys Glu Glu Pro Val Glu Ala Leu 
    770                 775                 780                 


Thr Phe Ser Arg Glu His Gly Pro Gly Val Ala Glu Pro Glu Val Ala 
785                 790                 795                 800 


Thr Ala Pro Pro Glu Lys Glu Ile Pro Ser Leu Asp Gln Glu Lys Thr 
                805                 810                 815     


Lys Leu Glu Pro Gly Gln Pro Gln Leu Ser Pro Gly Ile Ser Thr Ile 
            820                 825                 830         


His Leu His Pro Gln Phe Pro Val Val Ile Glu Lys Thr Ser Pro Pro 
        835                 840                 845             


Val Pro Val Glu Val Ala Pro Glu Ala Ser Thr Ser Ser Ala Ser Gln 
    850                 855                 860                 


Val Ile Ala Pro Thr Gln Val Thr Glu Ile Asn Glu Cys Thr Val Asn 
865                 870                 875                 880 


Pro Asp Ile Cys Gly Ala Gly His Cys Ile Asn Leu Pro Val Arg Tyr 
                885                 890                 895     


Thr Cys Ile Cys Tyr Glu Gly Tyr Arg Phe Ser Glu Gln Gln Arg Lys 
            900                 905                 910         


Cys Val Asp Ile Asp Glu Cys Thr Gln Val Gln His Leu Cys Ser Gln 
        915                 920                 925             


Gly Arg Cys Glu Asn Thr Glu Gly Ser Phe Leu Cys Ile Cys Pro Ala 
    930                 935                 940                 


Gly Phe Met Ala Ser Glu Glu Gly Thr Asn Cys Ile Asp Val Asp Glu 
945                 950                 955                 960 


Cys Leu Arg Pro Asp Val Cys Gly Glu Gly His Cys Val Asn Thr Val 
                965                 970                 975     


Gly Ala Phe Arg Cys Glu Tyr Cys Asp Ser Gly Tyr Arg Met Thr Gln 
            980                 985                 990         


Arg Gly Arg Cys Glu Asp Ile Asp  Glu Cys Leu Asn Pro  Ser Thr Cys 
        995                 1000                 1005             


Pro Asp  Glu Gln Cys Val Asn  Ser Pro Gly Ser Tyr  Gln Cys Val 
    1010                 1015                 1020             


Pro Cys  Thr Glu Gly Phe Arg  Gly Trp Asn Gly Gln  Cys Leu Asp 
    1025                 1030                 1035             


Val Asp  Glu Cys Leu Glu Pro  Asn Val Cys Ala Asn  Gly Asp Cys 
    1040                 1045                 1050             


Ser Asn  Leu Glu Gly Ser Tyr  Met Cys Ser Cys His  Lys Gly Tyr 
    1055                 1060                 1065             


Thr Arg  Thr Pro Asp His Lys  His Cys Arg Asp Ile  Asp Glu Cys 
    1070                 1075                 1080             


Gln Gln  Gly Asn Leu Cys Val  Asn Gly Gln Cys Lys  Asn Thr Glu 
    1085                 1090                 1095             


Gly Ser  Phe Arg Cys Thr Cys  Gly Gln Gly Tyr Gln  Leu Ser Ala 
    1100                 1105                 1110             


Ala Lys  Asp Gln Cys Glu Asp  Ile Asp Glu Cys Gln  His Arg His 
    1115                 1120                 1125             


Leu Cys  Ala His Gly Gln Cys  Arg Asn Thr Glu Gly  Ser Phe Gln 
    1130                 1135                 1140             


Cys Val  Cys Asp Gln Gly Tyr  Arg Ala Ser Gly Leu  Gly Asp His 
    1145                 1150                 1155             


Cys Glu  Asp Ile Asn Glu Cys  Leu Glu Asp Lys Ser  Val Cys Gln 
    1160                 1165                 1170             


Arg Gly  Asp Cys Ile Asn Thr  Ala Gly Ser Tyr Asp  Cys Thr Cys 
    1175                 1180                 1185             


Pro Asp  Gly Phe Gln Leu Asp  Asp Asn Lys Thr Cys  Gln Asp Ile 
    1190                 1195                 1200             


Asn Glu  Cys Glu His Pro Gly  Leu Cys Gly Pro Gln  Gly Glu Cys 
    1205                 1210                 1215             


Leu Asn  Thr Glu Gly Ser Phe  His Cys Val Cys Gln  Gln Gly Phe 
    1220                 1225                 1230             


Ser Ile  Ser Ala Asp Gly Arg  Thr Cys Glu Asp Ile  Asp Glu Cys 
    1235                 1240                 1245             


Val Asn  Asn Thr Val Cys Asp  Ser His Gly Phe Cys  Asp Asn Thr 
    1250                 1255                 1260             


Ala Gly  Ser Phe Arg Cys Leu  Cys Tyr Gln Gly Phe  Gln Ala Pro 
    1265                 1270                 1275             


Gln Asp  Gly Gln Gly Cys Val  Asp Val Asn Glu Cys  Glu Leu Leu 
    1280                 1285                 1290             


Ser Gly  Val Cys Gly Glu Ala  Phe Cys Glu Asn Val  Glu Gly Ser 
    1295                 1300                 1305             


Phe Leu  Cys Val Cys Ala Asp  Glu Asn Gln Glu Tyr  Ser Pro Met 
    1310                 1315                 1320             


Thr Gly  Gln Cys Arg Ser Arg  Thr Ser Thr Asp Leu  Asp Val Asp 
    1325                 1330                 1335             


Val Asp  Gln Pro Lys Glu Glu  Lys Lys Glu Cys Tyr  Tyr Asn Leu 
    1340                 1345                 1350             


Asn Asp  Ala Ser Leu Cys Asp  Asn Val Leu Ala Pro  Asn Val Thr 
    1355                 1360                 1365             


Lys Gln  Glu Cys Cys Cys Thr  Ser Gly Ala Gly Trp  Gly Asp Asn 
    1370                 1375                 1380             


Cys Glu  Ile Phe Pro Cys Pro  Val Leu Gly Thr Ala  Glu Phe Thr 
    1385                 1390                 1395             


Glu Met  Cys Pro Lys Gly Lys  Gly Phe Val Pro Ala  Gly Glu Ser 
    1400                 1405                 1410             


Ser Ser  Glu Ala Gly Gly Glu  Asn Tyr Lys Asp Ala  Asp Glu Cys 
    1415                 1420                 1425             


Leu Leu  Phe Gly Gln Glu Ile  Cys Lys Asn Gly Phe  Cys Leu Asn 
    1430                 1435                 1440             


Thr Arg  Pro Gly Tyr Glu Cys  Tyr Cys Lys Gln Gly  Thr Tyr Tyr 
    1445                 1450                 1455             


Asp Pro  Val Lys Leu Gln Cys  Phe Asp Met Asp Glu  Cys Gln Asp 
    1460                 1465                 1470             


Pro Ser  Ser Cys Ile Asp Gly  Gln Cys Val Asn Thr  Glu Gly Ser 
    1475                 1480                 1485             


Tyr Asn  Cys Phe Cys Thr His  Pro Met Val Leu Asp  Ala Ser Glu 
    1490                 1495                 1500             


Lys Arg  Cys Ile Arg Pro Ala  Glu Ser Asn Glu Gln  Ile Glu Glu 
    1505                 1510                 1515             


Thr Asp  Val Tyr Gln Asp Leu  Cys Trp Glu His Leu  Ser Asp Glu 
    1520                 1525                 1530             


Tyr Val  Cys Ser Arg Pro Leu  Val Gly Lys Gln Thr  Thr Tyr Thr 
    1535                 1540                 1545             


Glu Cys  Cys Cys Leu Tyr Gly  Glu Ala Trp Gly Met  Gln Cys Ala 
    1550                 1555                 1560             


Leu Cys  Pro Leu Lys Asp Ser  Asp Asp Tyr Ala Gln  Leu Cys Asn 
    1565                 1570                 1575             


Ile Pro  Val Thr Gly Arg Arg  Gln Pro Tyr Gly Arg  Asp Ala Leu 
    1580                 1585                 1590             


Val Asp  Phe Ser Glu Gln Tyr  Thr Pro Glu Ala Asp  Pro Tyr Phe 
    1595                 1600                 1605             


Ile Gln  Asp Arg Phe Leu Asn  Ser Phe Glu Glu Leu  Gln Ala Glu 
    1610                 1615                 1620             


Glu Cys  Gly Ile Leu Asn Gly  Cys Glu Asn Gly Arg  Cys Val Arg 
    1625                 1630                 1635             


Val Gln  Glu Gly Tyr Thr Cys  Asp Cys Phe Asp Gly  Tyr His Leu 
    1640                 1645                 1650             


Asp Thr  Ala Lys Met Thr Cys  Val Asp Val Asn Glu  Cys Asp Glu 
    1655                 1660                 1665             


Leu Asn  Asn Arg Met Ser Leu  Cys Lys Asn Ala Lys  Cys Ile Asn 
    1670                 1675                 1680             


Thr Asp  Gly Ser Tyr Lys Cys  Leu Cys Leu Pro Gly  Tyr Val Pro 
    1685                 1690                 1695             


Ser Asp  Lys Pro Asn Tyr Cys  Thr Pro Leu Asn Thr  Ala Leu Asn 
    1700                 1705                 1710             


Leu Glu  Lys Asp Ser Asp Leu  Glu 
    1715                 1720     


<210>  4273
<211>  468
<212>  PRT
<213>  homo sapiens

<400>  4273

Met Met Tyr Phe Val Ile Ala Ala Met Lys Ala Gln Ile Glu Ile Ile 
1               5                   10                  15      


Pro Cys Lys Ile Cys Gly Asp Lys Ser Ser Gly Ile His Tyr Gly Val 
            20                  25                  30          


Ile Thr Cys Glu Gly Cys Lys Gly Phe Phe Arg Arg Ser Gln Gln Ser 
        35                  40                  45              


Asn Ala Thr Tyr Ser Cys Pro Arg Gln Lys Asn Cys Leu Ile Asp Arg 
    50                  55                  60                  


Thr Ser Arg Asn Arg Cys Gln His Cys Arg Leu Gln Lys Cys Leu Ala 
65                  70                  75                  80  


Val Gly Met Ser Arg Asp Ala Val Lys Phe Gly Arg Met Ser Lys Lys 
                85                  90                  95      


Gln Arg Asp Ser Leu Tyr Ala Glu Val Gln Lys His Arg Met Gln Gln 
            100                 105                 110         


Gln Gln Arg Asp His Gln Gln Gln Pro Gly Glu Ala Glu Pro Leu Thr 
        115                 120                 125             


Pro Thr Tyr Asn Ile Ser Ala Asn Gly Leu Thr Glu Leu His Asp Asp 
    130                 135                 140                 


Leu Ser Asn Tyr Ile Asp Gly His Thr Pro Glu Gly Ser Lys Ala Asp 
145                 150                 155                 160 


Ser Ala Val Ser Ser Phe Tyr Leu Asp Ile Gln Pro Ser Pro Asp Gln 
                165                 170                 175     


Ser Gly Leu Asp Ile Asn Gly Ile Lys Pro Glu Pro Ile Cys Asp Tyr 
            180                 185                 190         


Thr Pro Ala Ser Gly Phe Phe Pro Tyr Cys Ser Phe Thr Asn Gly Glu 
        195                 200                 205             


Thr Ser Pro Thr Val Ser Met Ala Glu Leu Glu His Leu Ala Gln Asn 
    210                 215                 220                 


Ile Ser Lys Ser His Leu Glu Thr Cys Gln Tyr Leu Arg Glu Glu Leu 
225                 230                 235                 240 


Gln Gln Ile Thr Trp Gln Thr Phe Leu Gln Glu Glu Ile Glu Asn Tyr 
                245                 250                 255     


Gln Asn Lys Gln Arg Glu Val Met Trp Gln Leu Cys Ala Ile Lys Ile 
            260                 265                 270         


Thr Glu Ala Ile Gln Tyr Val Val Glu Phe Ala Lys Arg Ile Asp Gly 
        275                 280                 285             


Phe Met Glu Leu Cys Gln Asn Asp Gln Ile Val Leu Leu Lys Ala Gly 
    290                 295                 300                 


Ser Leu Glu Val Val Phe Ile Arg Met Cys Arg Ala Phe Asp Ser Gln 
305                 310                 315                 320 


Asn Asn Thr Val Tyr Phe Asp Gly Lys Tyr Ala Ser Pro Asp Val Phe 
                325                 330                 335     


Lys Ser Leu Gly Cys Glu Asp Phe Ile Ser Phe Val Phe Glu Phe Gly 
            340                 345                 350         


Lys Ser Leu Cys Ser Met His Leu Thr Glu Asp Glu Ile Ala Leu Phe 
        355                 360                 365             


Ser Ala Phe Val Leu Met Ser Ala Asp Arg Ser Trp Leu Gln Glu Lys 
    370                 375                 380                 


Val Lys Ile Glu Lys Leu Gln Gln Lys Ile Gln Leu Ala Leu Gln His 
385                 390                 395                 400 


Val Leu Gln Lys Asn His Arg Glu Asp Gly Ile Leu Thr Lys Leu Ile 
                405                 410                 415     


Cys Lys Val Ser Thr Leu Arg Ala Leu Cys Gly Arg His Thr Glu Lys 
            420                 425                 430         


Leu Met Ala Phe Lys Ala Ile Tyr Pro Asp Ile Val Arg Leu His Phe 
        435                 440                 445             


Pro Pro Leu Tyr Lys Glu Leu Phe Thr Ser Glu Phe Glu Pro Ala Met 
    450                 455                 460                 


Gln Ile Asp Gly 
465             


<210>  4274
<211>  676
<212>  PRT
<213>  homo sapiens

<400>  4274

Met Ser Asp Gln Ile Lys Phe Ile Met Asp Ser Leu Asn Lys Glu Pro 
1               5                   10                  15      


Phe Arg Lys Asn Tyr Asn Leu Ile Thr Phe Asp Ser Leu Glu Pro Met 
            20                  25                  30          


Gln Leu Leu Gln Val Leu Ser Asp Val Leu Ala Glu Ile Asp Pro Lys 
        35                  40                  45              


Gln Leu Val Asp Ile Arg Glu Glu Met Pro Glu Gln Thr Ala Lys Arg 
    50                  55                  60                  


Met Leu Ser Leu Leu Gly Ile Leu Lys Tyr Lys Pro Ser Gly Asn Ala 
65                  70                  75                  80  


Thr Asp Met Ser Thr Phe Arg Gln Gly Leu Val Ile Gly Ser Lys Pro 
                85                  90                  95      


Val Ile Tyr Pro Val Leu His Trp Leu Leu Gln Arg Thr Asn Glu Leu 
            100                 105                 110         


Lys Lys Arg Ala Tyr Leu Ala Arg Phe Leu Ile Lys Leu Glu Val Pro 
        115                 120                 125             


Ser Glu Phe Leu Gln Asp Glu Thr Val Ala Asp Thr Asn Lys Gln Tyr 
    130                 135                 140                 


Glu Glu Leu Met Glu Ala Phe Lys Thr Leu His Lys Glu Tyr Glu Gln 
145                 150                 155                 160 


Leu Lys Ile Ser Gly Phe Ser Thr Ala Glu Ile Arg Lys Asp Ile Ser 
                165                 170                 175     


Ala Met Glu Glu Glu Lys Asp Gln Leu Ile Lys Arg Val Glu His Leu 
            180                 185                 190         


Lys Lys Arg Val Glu Thr Ala Gln Asn His Gln Trp Met Leu Lys Ile 
        195                 200                 205             


Ala Arg Gln Leu Arg Val Glu Lys Glu Arg Glu Glu Tyr Leu Ala Gln 
    210                 215                 220                 


Gln Lys Gln Glu Gln Lys Asn Gln Leu Phe His Ala Val Gln Arg Leu 
225                 230                 235                 240 


Gln Arg Val Gln Asn Gln Leu Lys Ser Met Arg Gln Ala Ala Ala Asp 
                245                 250                 255     


Ala Lys Pro Glu Ser Leu Met Lys Arg Leu Glu Glu Glu Ile Lys Phe 
            260                 265                 270         


Asn Leu Tyr Met Val Thr Glu Lys Phe Pro Lys Glu Leu Glu Asn Lys 
        275                 280                 285             


Lys Lys Glu Leu His Phe Leu Gln Lys Val Val Ser Glu Pro Ala Met 
    290                 295                 300                 


Gly His Ser Asp Leu Leu Glu Leu Glu Ser Lys Ile Asn Glu Ile Asn 
305                 310                 315                 320 


Thr Glu Ile Asn Gln Leu Ile Glu Lys Lys Met Met Arg Asn Glu Pro 
                325                 330                 335     


Ile Glu Gly Lys Leu Ser Leu Tyr Arg Gln Gln Ala Ser Ile Ile Ser 
            340                 345                 350         


Arg Lys Lys Glu Ala Lys Ala Glu Glu Leu Gln Glu Ala Lys Glu Lys 
        355                 360                 365             


Leu Ala Ser Leu Glu Arg Glu Ala Ser Val Lys Arg Asn Gln Thr Arg 
    370                 375                 380                 


Glu Phe Asp Gly Thr Glu Val Leu Lys Gly Asp Glu Phe Lys Arg Tyr 
385                 390                 395                 400 


Val Asn Lys Leu Arg Ser Lys Ser Thr Val Phe Lys Lys Lys His Gln 
                405                 410                 415     


Ile Ile Ala Glu Leu Lys Ala Glu Phe Gly Leu Leu Gln Arg Thr Glu 
            420                 425                 430         


Glu Leu Leu Lys Gln Arg His Glu Asn Ile Gln Gln Gln Leu Gln Thr 
        435                 440                 445             


Met Glu Glu Lys Lys Gly Ile Ser Gly Tyr Ser Tyr Thr Gln Glu Glu 
    450                 455                 460                 


Leu Glu Arg Val Ser Ala Leu Lys Ser Glu Val Asp Glu Met Lys Gly 
465                 470                 475                 480 


Arg Thr Leu Asp Asp Met Ser Glu Met Val Lys Lys Leu Tyr Ser Leu 
                485                 490                 495     


Val Ser Glu Lys Lys Ser Ala Leu Ala Ser Val Ile Lys Glu Leu Arg 
            500                 505                 510         


Gln Leu Arg Gln Lys Tyr Gln Glu Leu Thr Gln Glu Cys Asp Glu Lys 
        515                 520                 525             


Lys Ser Gln Tyr Asp Ser Cys Ala Ala Gly Leu Glu Ser Asn Arg Ser 
    530                 535                 540                 


Lys Leu Glu Gln Glu Val Arg Arg Leu Arg Glu Glu Cys Leu Gln Glu 
545                 550                 555                 560 


Glu Ser Arg Tyr His Tyr Thr Asn Cys Met Ile Lys Asn Leu Glu Val 
                565                 570                 575     


Gln Leu Arg Arg Ala Thr Asp Glu Met Lys Ala Tyr Ile Ser Ser Asp 
            580                 585                 590         


Gln Gln Glu Lys Arg Lys Ala Ile Arg Glu Gln Tyr Thr Lys Asn Thr 
        595                 600                 605             


Ala Glu Gln Glu Asn Leu Gly Lys Lys Leu Arg Glu Lys Gln Lys Val 
    610                 615                 620                 


Ile Arg Glu Ser His Gly Pro Asn Met Lys Gln Ala Lys Met Trp Arg 
625                 630                 635                 640 


Asp Leu Glu Gln Leu Met Glu Cys Lys Lys Gln Cys Phe Leu Lys Gln 
                645                 650                 655     


Gln Ser Gln Thr Ser Ile Gly Gln Val Ile Gln Glu Gly Gly Glu Asp 
            660                 665                 670         


Arg Leu Ile Leu 
        675     


<210>  4275
<211>  445
<212>  PRT
<213>  homo sapiens

<400>  4275

Met Ser Lys Leu Pro Arg Glu Leu Thr Arg Asp Leu Glu Arg Ser Leu 
1               5                   10                  15      


Pro Ala Val Ala Ser Leu Gly Ser Ser Leu Ser His Ser Gln Ser Leu 
            20                  25                  30          


Ser Ser His Leu Leu Pro Pro Pro Glu Lys Arg Arg Ala Ile Ser Asp 
        35                  40                  45              


Val Arg Arg Thr Phe Cys Leu Phe Val Thr Phe Asp Leu Leu Phe Ile 
    50                  55                  60                  


Ser Leu Leu Trp Ile Ile Glu Leu Asn Thr Asn Thr Gly Ile Arg Lys 
65                  70                  75                  80  


Asn Leu Glu Gln Glu Ile Ile Gln Tyr Asn Phe Lys Thr Ser Phe Phe 
                85                  90                  95      


Asp Ile Phe Val Leu Ala Phe Phe Arg Phe Ser Gly Leu Leu Leu Gly 
            100                 105                 110         


Tyr Ala Val Leu Arg Leu Arg His Trp Trp Val Ile Ala Val Thr Thr 
        115                 120                 125             


Leu Val Ser Ser Ala Phe Leu Ile Val Lys Val Ile Leu Ser Glu Leu 
    130                 135                 140                 


Leu Ser Lys Gly Ala Phe Gly Tyr Leu Leu Pro Ile Val Ser Phe Val 
145                 150                 155                 160 


Leu Ala Trp Leu Glu Thr Trp Phe Leu Asp Phe Lys Val Leu Pro Gln 
                165                 170                 175     


Glu Ala Glu Glu Glu Arg Trp Tyr Leu Ala Ala Gln Val Ala Val Ala 
            180                 185                 190         


Arg Gly Pro Leu Leu Phe Ser Gly Ala Leu Ser Glu Gly Gln Phe Tyr 
        195                 200                 205             


Ser Pro Pro Glu Ser Phe Ala Gly Ser Asp Asn Glu Ser Asp Glu Glu 
    210                 215                 220                 


Val Ala Gly Lys Lys Ser Phe Ser Ala Gln Glu Arg Glu Tyr Ile Arg 
225                 230                 235                 240 


Gln Gly Lys Glu Ala Thr Ala Val Val Asp Gln Ile Leu Ala Gln Glu 
                245                 250                 255     


Glu Asn Trp Lys Phe Glu Lys Asn Asn Glu Tyr Gly Asp Thr Val Tyr 
            260                 265                 270         


Thr Ile Glu Val Pro Phe His Gly Lys Thr Phe Ile Leu Lys Thr Phe 
        275                 280                 285             


Leu Pro Cys Pro Ala Glu Leu Val Tyr Gln Glu Val Ile Leu Gln Pro 
    290                 295                 300                 


Glu Arg Met Val Leu Trp Asn Lys Thr Val Thr Ala Cys Gln Ile Leu 
305                 310                 315                 320 


Gln Arg Val Glu Asp Asn Thr Leu Ile Ser Tyr Asp Val Ser Ala Gly 
                325                 330                 335     


Ala Ala Gly Gly Val Val Ser Pro Arg Asp Phe Val Asn Val Arg Arg 
            340                 345                 350         


Ile Glu Arg Arg Arg Asp Arg Tyr Leu Ser Ser Gly Ile Ala Thr Ser 
        355                 360                 365             


His Ser Ala Lys Pro Pro Thr His Lys Tyr Val Arg Gly Glu Asn Gly 
    370                 375                 380                 


Pro Gly Gly Phe Ile Val Leu Lys Ser Ala Ser Asn Pro Arg Val Cys 
385                 390                 395                 400 


Thr Phe Val Trp Ile Leu Asn Thr Asp Leu Lys Gly Arg Leu Pro Arg 
                405                 410                 415     


Tyr Leu Ile His Gln Ser Leu Ala Ala Thr Met Phe Glu Phe Ala Phe 
            420                 425                 430         


His Leu Arg Gln Arg Ile Ser Glu Leu Gly Ala Arg Ala 
        435                 440                 445 


<210>  4276
<211>  445
<212>  PRT
<213>  homo sapiens

<400>  4276

Met Ser Lys Leu Pro Arg Glu Leu Thr Arg Asp Leu Glu Arg Ser Leu 
1               5                   10                  15      


Pro Ala Val Ala Ser Leu Gly Ser Ser Leu Ser His Ser Gln Ser Leu 
            20                  25                  30          


Ser Ser His Leu Leu Pro Pro Pro Glu Lys Arg Arg Ala Ile Ser Asp 
        35                  40                  45              


Val Arg Arg Thr Phe Cys Leu Phe Val Thr Phe Asp Leu Leu Phe Ile 
    50                  55                  60                  


Ser Leu Leu Trp Ile Ile Glu Leu Asn Thr Asn Thr Gly Ile Arg Lys 
65                  70                  75                  80  


Asn Leu Glu Gln Glu Ile Ile Gln Tyr Asn Phe Lys Thr Ser Phe Phe 
                85                  90                  95      


Asp Ile Phe Val Leu Ala Phe Phe Arg Phe Ser Gly Leu Leu Leu Gly 
            100                 105                 110         


Tyr Ala Val Leu Arg Leu Arg His Trp Ser Arg Arg Trp Cys Pro Val 
        115                 120                 125             


His Ser Ser Leu Ser Arg Ser Ser Ser Leu Ser Cys Ser Ala Lys Gly 
    130                 135                 140                 


His Leu Ala Thr Cys Ser Pro Ser Ser Leu Leu Ser Ser Pro Gly Trp 
145                 150                 155                 160 


Arg Pro Gly Ser Leu Thr Ser Lys Ser Tyr Pro Arg Lys Leu Lys Arg 
                165                 170                 175     


Ser Asp Ser Ala Pro Pro Gly Tyr Leu Ala Ala Gln Val Ala Val Ala 
            180                 185                 190         


Arg Gly Pro Leu Leu Phe Ser Gly Ala Leu Ser Glu Gly Gln Phe Tyr 
        195                 200                 205             


Ser Pro Pro Glu Ser Phe Ala Gly Ser Asp Asn Glu Ser Asp Glu Glu 
    210                 215                 220                 


Val Ala Gly Lys Lys Ser Phe Ser Ala Gln Glu Arg Glu Tyr Ile Arg 
225                 230                 235                 240 


Gln Gly Lys Glu Ala Thr Ala Val Val Asp Gln Ile Leu Ala Gln Glu 
                245                 250                 255     


Glu Asn Trp Lys Phe Glu Lys Asn Asn Glu Tyr Gly Asp Thr Val Tyr 
            260                 265                 270         


Thr Ile Glu Val Pro Phe His Gly Lys Thr Phe Ile Leu Lys Thr Phe 
        275                 280                 285             


Leu Pro Cys Pro Ala Glu Leu Val Tyr Gln Glu Val Ile Leu Gln Pro 
    290                 295                 300                 


Glu Arg Met Val Leu Trp Asn Lys Thr Val Thr Ala Cys Gln Ile Leu 
305                 310                 315                 320 


Gln Arg Val Glu Asp Asn Thr Leu Ile Ser Tyr Asp Val Ser Ala Gly 
                325                 330                 335     


Ala Ala Gly Gly Val Val Ser Pro Arg Asp Phe Val Asn Val Arg Arg 
            340                 345                 350         


Ile Glu Arg Arg Arg Asp Arg Tyr Leu Ser Ser Gly Ile Ala Thr Ser 
        355                 360                 365             


His Ser Ala Lys Pro Pro Thr His Lys Tyr Val Arg Gly Glu Asn Gly 
    370                 375                 380                 


Pro Gly Gly Phe Ile Val Leu Lys Ser Ala Ser Asn Pro Arg Val Cys 
385                 390                 395                 400 


Thr Phe Val Trp Ile Leu Asn Thr Asp Leu Lys Gly Arg Leu Pro Arg 
                405                 410                 415     


Tyr Leu Ile His Gln Ser Leu Ala Ala Thr Met Phe Glu Phe Ala Phe 
            420                 425                 430         


His Leu Arg Gln Arg Ile Ser Glu Leu Gly Ala Arg Ala 
        435                 440                 445 


<210>  4277
<211>  329
<212>  PRT
<213>  homo sapiens

<400>  4277

Met Val Arg Thr Lys Thr Trp Thr Leu Lys Lys His Phe Val Gly Tyr 
1               5                   10                  15      


Pro Thr Asn Ser Asp Phe Glu Leu Lys Thr Ala Glu Leu Pro Pro Leu 
            20                  25                  30          


Lys Asn Gly Glu Val Leu Leu Glu Ala Leu Phe Leu Thr Val Asp Pro 
        35                  40                  45              


Tyr Met Arg Val Ala Ala Lys Arg Leu Lys Glu Gly Asp Thr Met Met 
    50                  55                  60                  


Gly Gln Gln Val Ala Lys Val Val Glu Ser Lys Asn Val Ala Leu Pro 
65                  70                  75                  80  


Lys Gly Thr Ile Val Leu Ala Ser Pro Gly Trp Thr Thr His Ser Ile 
                85                  90                  95      


Ser Asp Gly Lys Asp Leu Glu Lys Leu Leu Thr Glu Trp Pro Asp Thr 
            100                 105                 110         


Ile Pro Leu Ser Leu Ala Leu Gly Thr Val Gly Met Pro Gly Leu Thr 
        115                 120                 125             


Ala Tyr Phe Gly Leu Leu Glu Ile Cys Gly Val Lys Gly Gly Glu Thr 
    130                 135                 140                 


Val Met Val Asn Ala Ala Ala Gly Ala Val Gly Ser Val Val Gly Gln 
145                 150                 155                 160 


Ile Ala Lys Leu Lys Gly Cys Lys Val Val Gly Ala Val Gly Ser Asp 
                165                 170                 175     


Glu Lys Val Ala Tyr Leu Gln Lys Leu Gly Phe Asp Val Val Phe Asn 
            180                 185                 190         


Tyr Lys Thr Val Glu Ser Leu Glu Glu Thr Leu Lys Lys Ala Ser Pro 
        195                 200                 205             


Asp Gly Tyr Asp Cys Tyr Phe Asp Asn Val Gly Gly Glu Phe Ser Asn 
    210                 215                 220                 


Thr Val Ile Gly Gln Met Lys Lys Phe Gly Arg Ile Ala Ile Cys Gly 
225                 230                 235                 240 


Ala Ile Ser Thr Tyr Asn Arg Thr Gly Pro Leu Pro Pro Gly Pro Pro 
                245                 250                 255     


Pro Glu Ile Val Ile Tyr Gln Glu Leu Arg Met Glu Ala Phe Val Val 
            260                 265                 270         


Tyr Arg Trp Gln Gly Asp Ala Arg Gln Lys Ala Leu Lys Asp Leu Leu 
        275                 280                 285             


Lys Trp Val Leu Glu Gly Lys Ile Gln Tyr Lys Glu Tyr Ile Ile Glu 
    290                 295                 300                 


Gly Phe Glu Asn Met Pro Ala Ala Phe Met Gly Met Leu Lys Gly Asp 
305                 310                 315                 320 


Asn Leu Gly Lys Thr Ile Val Lys Ala 
                325                 


<210>  4278
<211>  2466
<212>  PRT
<213>  homo sapiens

<400>  4278

Met His Val Ser Leu Ala Glu Ala Leu Glu Val Arg Gly Gly Pro Leu 
1               5                   10                  15      


Gln Glu Glu Glu Ile Trp Ala Val Leu Asn Gln Ser Ala Glu Ser Leu 
            20                  25                  30          


Gln Glu Leu Phe Arg Lys Val Ser Leu Ala Asp Pro Ala Ala Leu Gly 
        35                  40                  45              


Phe Ile Ile Ser Pro Trp Ser Leu Leu Leu Leu Pro Ser Gly Ser Val 
    50                  55                  60                  


Ser Phe Thr Asp Glu Asn Ile Ser Asn Gln Asp Leu Arg Ala Phe Thr 
65                  70                  75                  80  


Ala Pro Glu Val Leu Gln Asn Gln Ser Leu Thr Ser Leu Ser Asp Val 
                85                  90                  95      


Glu Lys Ile His Ile Tyr Ser Leu Gly Met Thr Leu Tyr Trp Gly Ala 
            100                 105                 110         


Asp Tyr Glu Val Pro Gln Ser Gln Pro Ile Lys Leu Gly Asp His Leu 
        115                 120                 125             


Asn Ser Ile Leu Leu Gly Met Cys Glu Asp Val Ile Tyr Ala Arg Val 
    130                 135                 140                 


Ser Val Arg Thr Val Leu Asp Ala Cys Ser Ala His Ile Arg Asn Ser 
145                 150                 155                 160 


Asn Cys Ala Pro Ser Phe Ser Tyr Val Lys His Leu Val Lys Leu Val 
                165                 170                 175     


Leu Gly Asn Leu Ser Gly Thr Asp Gln Leu Ser Cys Asn Ser Glu Gln 
            180                 185                 190         


Lys Pro Asp Arg Ser Gln Ala Ile Arg Asp Arg Leu Arg Gly Lys Gly 
        195                 200                 205             


Leu Pro Thr Gly Arg Ser Ser Thr Ser Asp Val Leu Asp Ile Gln Lys 
    210                 215                 220                 


Pro Pro Leu Ser His Gln Thr Phe Leu Asn Lys Gly Leu Ser Lys Ser 
225                 230                 235                 240 


Met Gly Phe Leu Ser Ile Lys Asp Thr Gln Asp Glu Asn Tyr Phe Lys 
                245                 250                 255     


Asp Ile Leu Ser Asp Asn Ser Gly Arg Glu Asp Ser Glu Asn Thr Phe 
            260                 265                 270         


Ser Pro Tyr Gln Phe Lys Thr Ser Gly Pro Glu Lys Lys Pro Ile Pro 
        275                 280                 285             


Gly Ile Asp Val Leu Ser Lys Lys Lys Ile Trp Ala Ser Ser Met Asp 
    290                 295                 300                 


Leu Leu Cys Thr Ala Asp Arg Asp Phe Ser Ser Gly Glu Thr Ala Thr 
305                 310                 315                 320 


Tyr Arg Arg Cys His Pro Glu Ala Val Thr Val Arg Thr Ser Thr Thr 
                325                 330                 335     


Pro Arg Lys Lys Glu Ala Arg Tyr Ser Asp Gly Ser Ile Ala Leu Asp 
            340                 345                 350         


Ile Phe Gly Pro Gln Lys Met Asp Pro Ile Tyr His Thr Arg Glu Leu 
        355                 360                 365             


Pro Thr Ser Ser Ala Ile Ser Ser Ala Leu Asp Arg Ile Arg Glu Arg 
    370                 375                 380                 


Gln Lys Lys Leu Gln Val Leu Arg Glu Ala Met Asn Val Glu Glu Pro 
385                 390                 395                 400 


Val Arg Arg Tyr Lys Thr Tyr His Gly Asp Val Phe Ser Thr Ser Ser 
                405                 410                 415     


Glu Ser Pro Ser Ile Ile Ser Ser Glu Ser Asp Phe Arg Gln Val Arg 
            420                 425                 430         


Arg Ser Glu Ala Ser Lys Arg Phe Glu Ser Ser Ser Gly Leu Pro Gly 
        435                 440                 445             


Val Asp Glu Thr Leu Ser Gln Gly Gln Ser Gln Arg Pro Ser Arg Gln 
    450                 455                 460                 


Tyr Glu Thr Pro Phe Glu Gly Asn Leu Ile Asn Gln Glu Ile Met Leu 
465                 470                 475                 480 


Lys Arg Gln Glu Glu Glu Leu Met Gln Leu Gln Ala Lys Met Ala Leu 
                485                 490                 495     


Arg Gln Ser Arg Leu Ser Leu Tyr Pro Gly Asp Thr Ile Lys Ala Ser 
            500                 505                 510         


Met Leu Asp Ile Thr Arg Asp Pro Leu Arg Glu Ile Ala Leu Glu Thr 
        515                 520                 525             


Ala Met Thr Gln Arg Lys Leu Arg Asn Phe Phe Gly Pro Glu Phe Val 
    530                 535                 540                 


Lys Met Thr Ile Glu Pro Phe Ile Ser Leu Asp Leu Pro Arg Ser Ile 
545                 550                 555                 560 


Leu Thr Lys Lys Gly Lys Asn Glu Asp Asn Arg Arg Lys Val Asn Ile 
                565                 570                 575     


Met Leu Leu Asn Gly Gln Arg Leu Glu Leu Thr Cys Asp Thr Lys Thr 
            580                 585                 590         


Ile Cys Lys Asp Val Phe Asp Met Val Val Ala His Ile Gly Leu Val 
        595                 600                 605             


Glu His His Leu Phe Ala Leu Ala Thr Leu Lys Asp Asn Glu Tyr Phe 
    610                 615                 620                 


Phe Val Asp Pro Asp Leu Lys Leu Thr Lys Val Ala Pro Glu Gly Trp 
625                 630                 635                 640 


Lys Glu Glu Pro Lys Lys Lys Thr Lys Ala Thr Val Asn Phe Thr Leu 
                645                 650                 655     


Phe Phe Arg Ile Lys Phe Phe Met Asp Asp Val Ser Leu Ile Gln His 
            660                 665                 670         


Thr Leu Thr Cys His Gln Tyr Tyr Leu Gln Leu Arg Lys Asp Ile Leu 
        675                 680                 685             


Glu Glu Arg Met His Cys Asp Asp Glu Thr Ser Leu Leu Leu Ala Ser 
    690                 695                 700                 


Leu Ala Leu Gln Ala Glu Tyr Gly Asp Tyr Gln Pro Glu Val His Gly 
705                 710                 715                 720 


Val Ser Tyr Phe Arg Met Glu His Tyr Leu Pro Ala Arg Val Met Glu 
                725                 730                 735     


Lys Leu Asp Leu Ser Tyr Ile Lys Glu Glu Leu Pro Lys Leu His Asn 
            740                 745                 750         


Thr Tyr Val Gly Ala Ser Glu Lys Glu Thr Glu Leu Glu Phe Leu Lys 
        755                 760                 765             


Val Cys Gln Arg Leu Thr Glu Tyr Gly Val His Phe His Arg Val His 
    770                 775                 780                 


Pro Glu Lys Lys Ser Gln Thr Gly Ile Leu Leu Gly Val Cys Ser Lys 
785                 790                 795                 800 


Gly Val Leu Val Phe Glu Val His Asn Gly Val Arg Thr Leu Val Leu 
                805                 810                 815     


Arg Phe Pro Trp Arg Glu Thr Lys Lys Ile Ser Phe Ser Lys Lys Lys 
            820                 825                 830         


Ile Thr Leu Gln Asn Thr Ser Asp Gly Ile Lys His Gly Phe Gln Thr 
        835                 840                 845             


Asp Asn Ser Lys Ile Cys Gln Tyr Leu Leu His Leu Cys Ser Tyr Gln 
    850                 855                 860                 


His Lys Phe Gln Leu Gln Met Arg Ala Arg Gln Ser Asn Gln Asp Ala 
865                 870                 875                 880 


Gln Asp Ile Glu Arg Ala Ser Phe Arg Ser Leu Asn Leu Gln Ala Glu 
                885                 890                 895     


Ser Val Arg Gly Phe Asn Met Gly Arg Ala Ile Ser Thr Gly Ser Leu 
            900                 905                 910         


Ala Ser Ser Thr Leu Asn Lys Leu Ala Val Arg Pro Leu Ser Val Gln 
        915                 920                 925             


Ala Glu Ile Leu Lys Arg Leu Ser Cys Ser Glu Leu Ser Leu Tyr Gln 
    930                 935                 940                 


Pro Leu Gln Asn Ser Ser Lys Glu Lys Asn Asp Lys Ala Ser Trp Glu 
945                 950                 955                 960 


Glu Lys Pro Arg Glu Met Ser Lys Ser Tyr His Asp Leu Ser Gln Ala 
                965                 970                 975     


Ser Leu Tyr Pro His Arg Lys Asn Val Ile Val Asn Met Glu Pro Pro 
            980                 985                 990         


Pro Gln Thr Val Ala Glu Leu Val  Gly Lys Pro Ser His  Gln Met Ser 
        995                 1000                 1005             


Arg Ser  Asp Ala Glu Ser Leu  Ala Gly Val Thr Lys  Leu Asn Asn 
    1010                 1015                 1020             


Ser Lys  Ser Val Ala Ser Leu  Asn Arg Ser Pro Glu  Arg Arg Lys 
    1025                 1030                 1035             


His Glu  Ser Asp Ser Ser Ser  Ile Glu Asp Pro Gly  Gln Ala Tyr 
    1040                 1045                 1050             


Val Leu  Asp Val Leu His Lys  Arg Trp Ser Ile Val  Ser Ser Pro 
    1055                 1060                 1065             


Glu Arg  Glu Ile Thr Leu Val  Asn Leu Lys Lys Asp  Ala Lys Tyr 
    1070                 1075                 1080             


Gly Leu  Gly Phe Gln Ile Ile  Gly Gly Glu Lys Met  Gly Arg Leu 
    1085                 1090                 1095             


Asp Leu  Gly Ile Phe Ile Ser  Ser Val Ala Pro Gly  Gly Pro Ala 
    1100                 1105                 1110             


Asp Leu  Asp Gly Cys Leu Lys  Pro Gly Asp Arg Leu  Ile Ser Val 
    1115                 1120                 1125             


Asn Ser  Val Ser Leu Glu Gly  Val Ser His His Ala  Ala Ile Glu 
    1130                 1135                 1140             


Ile Leu  Gln Asn Ala Pro Glu  Asp Val Thr Leu Val  Ile Ser Gln 
    1145                 1150                 1155             


Pro Lys  Glu Lys Ile Ser Lys  Val Pro Ser Thr Pro  Val His Leu 
    1160                 1165                 1170             


Thr Asn  Glu Met Lys Asn Tyr  Met Lys Lys Ser Ser  Tyr Met Gln 
    1175                 1180                 1185             


Asp Ser  Ala Ile Asp Ser Ser  Ser Lys Asp His His  Trp Ser Arg 
    1190                 1195                 1200             


Gly Thr  Leu Arg His Ile Ser  Glu Asn Ser Phe Gly  Pro Ser Gly 
    1205                 1210                 1215             


Gly Leu  Arg Glu Gly Ser Leu  Ser Ser Gln Asp Ser  Arg Thr Glu 
    1220                 1225                 1230             


Ser Ala  Ser Leu Ser Gln Ser  Gln Val Asn Gly Phe  Phe Ala Ser 
    1235                 1240                 1245             


His Leu  Gly Asp Gln Thr Trp  Gln Glu Ser Gln His  Gly Ser Pro 
    1250                 1255                 1260             


Ser Pro  Ser Val Ile Ser Lys  Ala Thr Glu Lys Glu  Thr Phe Thr 
    1265                 1270                 1275             


Asp Ser  Asn Gln Ser Lys Thr  Lys Lys Pro Gly Ile  Ser Asp Val 
    1280                 1285                 1290             


Thr Asp  Tyr Ser Asp Arg Gly  Asp Ser Asp Met Asp  Glu Ala Thr 
    1295                 1300                 1305             


Tyr Ser  Ser Ser Gln Asp His  Gln Thr Pro Lys Gln  Glu Ser Ser 
    1310                 1315                 1320             


Ser Ser  Val Asn Thr Ser Asn  Lys Met Asn Phe Lys  Thr Phe Ser 
    1325                 1330                 1335             


Ser Ser  Pro Pro Lys Pro Gly  Asp Ile Phe Glu Val  Glu Leu Ala 
    1340                 1345                 1350             


Lys Asn  Asp Asn Ser Leu Gly  Ile Ser Val Thr Gly  Gly Val Asn 
    1355                 1360                 1365             


Thr Ser  Val Arg His Gly Gly  Ile Tyr Val Lys Ala  Val Ile Pro 
    1370                 1375                 1380             


Gln Gly  Ala Ala Glu Ser Asp  Gly Arg Ile His Lys  Gly Asp Arg 
    1385                 1390                 1395             


Val Leu  Ala Val Asn Gly Val  Ser Leu Glu Gly Ala  Thr His Lys 
    1400                 1405                 1410             


Gln Ala  Val Glu Thr Leu Arg  Asn Thr Gly Gln Val  Val His Leu 
    1415                 1420                 1425             


Leu Leu  Glu Lys Gly Gln Ser  Pro Thr Ser Lys Glu  His Val Pro 
    1430                 1435                 1440             


Val Thr  Pro Gln Cys Thr Leu  Ser Asp Gln Asn Ala  Gln Gly Gln 
    1445                 1450                 1455             


Gly Pro  Glu Lys Val Lys Lys  Thr Thr Gln Val Lys  Asp Tyr Ser 
    1460                 1465                 1470             


Phe Val  Thr Glu Glu Asn Thr  Phe Glu Val Lys Leu  Phe Lys Asn 
    1475                 1480                 1485             


Ser Ser  Gly Leu Gly Phe Ser  Phe Ser Arg Glu Asp  Asn Leu Ile 
    1490                 1495                 1500             


Pro Glu  Gln Ile Asn Ala Ser  Ile Val Arg Val Lys  Lys Leu Phe 
    1505                 1510                 1515             


Pro Gly  Gln Pro Ala Ala Glu  Ser Gly Lys Ile Asp  Val Gly Asp 
    1520                 1525                 1530             


Val Ile  Leu Lys Val Asn Gly  Ala Ser Leu Lys Gly  Leu Ser Gln 
    1535                 1540                 1545             


Gln Glu  Val Ile Ser Ala Leu  Arg Gly Thr Ala Pro  Glu Val Phe 
    1550                 1555                 1560             


Leu Leu  Leu Cys Arg Pro Pro  Pro Gly Val Leu Pro  Glu Ile Asp 
    1565                 1570                 1575             


Thr Ala  Leu Leu Thr Pro Leu  Gln Ser Pro Ala Gln  Val Leu Pro 
    1580                 1585                 1590             


Asn Ser  Ser Lys Asp Ser Ser  Gln Pro Ser Cys Val  Glu Gln Ser 
    1595                 1600                 1605             


Thr Ser  Ser Asp Glu Asn Glu  Met Ser Asp Lys Ser  Lys Lys Gln 
    1610                 1615                 1620             


Cys Lys  Ser Pro Ser Arg Arg  Asp Ser Tyr Ser Asp  Ser Ser Gly 
    1625                 1630                 1635             


Ser Gly  Glu Asp Asp Leu Val  Thr Ala Pro Ala Asn  Ile Ser Asn 
    1640                 1645                 1650             


Ser Thr  Trp Ser Ser Ala Leu  His Gln Thr Leu Ser  Asn Met Val 
    1655                 1660                 1665             


Ser Gln  Ala Gln Ser His His  Glu Ala Pro Lys Ser  Gln Glu Asp 
    1670                 1675                 1680             


Thr Ile  Cys Thr Met Phe Tyr  Tyr Pro Gln Lys Ile  Pro Asn Lys 
    1685                 1690                 1695             


Pro Glu  Phe Glu Asp Ser Asn  Pro Ser Pro Leu Pro  Pro Asp Met 
    1700                 1705                 1710             


Ala Pro  Gly Gln Ser Tyr Gln  Pro Gln Ser Glu Ser  Ala Ser Ser 
    1715                 1720                 1725             


Ser Ser  Met Asp Lys Tyr His  Ile His His Ile Ser  Glu Pro Thr 
    1730                 1735                 1740             


Arg Gln  Glu Asn Trp Thr Pro  Leu Lys Asn Asp Leu  Glu Asn His 
    1745                 1750                 1755             


Leu Glu  Asp Phe Glu Leu Glu  Val Glu Leu Leu Ile  Thr Leu Ile 
    1760                 1765                 1770             


Lys Ser  Glu Lys Gly Ser Leu  Gly Phe Thr Val Thr  Lys Gly Asn 
    1775                 1780                 1785             


Gln Arg  Ile Gly Cys Tyr Val  His Asp Val Ile Gln  Asp Pro Ala 
    1790                 1795                 1800             


Lys Ser  Asp Gly Arg Leu Lys  Pro Gly Asp Arg Leu  Ile Lys Val 
    1805                 1810                 1815             


Asn Asp  Thr Asp Val Thr Asn  Met Thr His Thr Asp  Ala Val Asn 
    1820                 1825                 1830             


Leu Leu  Arg Ala Ala Ser Lys  Thr Val Arg Leu Val  Ile Gly Arg 
    1835                 1840                 1845             


Val Leu  Glu Leu Pro Arg Ile  Pro Met Leu Pro His  Leu Leu Pro 
    1850                 1855                 1860             


Asp Ile  Thr Leu Thr Cys Asn  Lys Glu Glu Leu Gly  Phe Ser Leu 
    1865                 1870                 1875             


Cys Gly  Gly His Asp Ser Leu  Tyr Gln Val Val Tyr  Ile Ser Asp 
    1880                 1885                 1890             


Ile Asn  Pro Arg Ser Val Ala  Ala Ile Glu Gly Asn  Leu Gln Leu 
    1895                 1900                 1905             


Leu Asp  Val Ile His Tyr Val  Asn Gly Val Ser Thr  Gln Gly Met 
    1910                 1915                 1920             


Thr Leu  Glu Glu Val Asn Arg  Ala Leu Asp Met Ser  Leu Pro Ser 
    1925                 1930                 1935             


Leu Val  Leu Lys Ala Thr Arg  Asn Asp Leu Pro Val  Val Pro Ser 
    1940                 1945                 1950             


Ser Lys  Arg Ser Ala Val Ser  Ala Pro Lys Ser Thr  Lys Gly Asn 
    1955                 1960                 1965             


Gly Ser  Tyr Ser Val Gly Ser  Cys Ser Gln Pro Ala  Leu Thr Pro 
    1970                 1975                 1980             


Asn Asp  Ser Phe Ser Thr Val  Ala Gly Glu Glu Ile  Asn Glu Ile 
    1985                 1990                 1995             


Ser Tyr  Pro Lys Gly Lys Cys  Ser Thr Tyr Gln Ile  Lys Gly Ser 
    2000                 2005                 2010             


Pro Asn  Leu Thr Leu Pro Lys  Glu Ser Tyr Ile Gln  Glu Asp Asp 
    2015                 2020                 2025             


Ile Tyr  Asp Asp Ser Gln Glu  Ala Glu Val Ile Gln  Ser Leu Leu 
    2030                 2035                 2040             


Asp Val  Val Asp Glu Glu Ala  Gln Asn Leu Leu Asn  Glu Asn Asn 
    2045                 2050                 2055             


Ala Ala  Gly Tyr Ser Cys Gly  Pro Gly Thr Leu Lys  Met Asn Gly 
    2060                 2065                 2070             


Lys Leu  Ser Glu Glu Arg Thr  Glu Asp Thr Asp Cys  Asp Gly Ser 
    2075                 2080                 2085             


Pro Leu  Pro Glu Tyr Phe Thr  Glu Ala Thr Lys Met  Asn Gly Cys 
    2090                 2095                 2100             


Glu Glu  Tyr Cys Glu Glu Lys  Val Lys Ser Glu Ser  Leu Ile Gln 
    2105                 2110                 2115             


Lys Pro  Gln Glu Lys Lys Thr  Asp Asp Asp Glu Ile  Thr Trp Gly 
    2120                 2125                 2130             


Asn Asp  Glu Leu Pro Ile Glu  Arg Thr Asn His Glu  Asp Ser Asp 
    2135                 2140                 2145             


Lys Asp  His Ser Phe Leu Thr  Asn Asp Glu Leu Ala  Val Leu Pro 
    2150                 2155                 2160             


Val Val  Lys Val Leu Pro Ser  Gly Lys Tyr Thr Gly  Ala Asn Leu 
    2165                 2170                 2175             


Lys Ser  Val Ile Arg Val Leu  Arg Gly Leu Leu Asp  Gln Gly Ile 
    2180                 2185                 2190             


Pro Ser  Lys Glu Leu Glu Asn  Leu Gln Glu Leu Lys  Pro Leu Asp 
    2195                 2200                 2205             


Gln Cys  Leu Ile Gly Gln Thr  Lys Glu Asn Arg Arg  Lys Asn Arg 
    2210                 2215                 2220             


Tyr Lys  Asn Ile Leu Pro Tyr  Asp Ala Thr Arg Val  Pro Leu Gly 
    2225                 2230                 2235             


Asp Glu  Gly Gly Tyr Ile Asn  Ala Ser Phe Ile Lys  Ile Pro Val 
    2240                 2245                 2250             


Gly Lys  Glu Glu Phe Val Tyr  Ile Ala Cys Gln Gly  Pro Leu Pro 
    2255                 2260                 2265             


Thr Thr  Val Gly Asp Phe Trp  Gln Met Ile Trp Glu  Gln Lys Ser 
    2270                 2275                 2280             


Thr Val  Ile Ala Met Met Thr  Gln Glu Val Glu Gly  Glu Lys Ile 
    2285                 2290                 2295             


Lys Cys  Gln Arg Tyr Trp Pro  Asn Ile Leu Gly Lys  Thr Thr Met 
    2300                 2305                 2310             


Val Ser  Asn Arg Leu Arg Leu  Ala Leu Val Arg Met  Gln Gln Leu 
    2315                 2320                 2325             


Lys Gly  Phe Val Val Arg Ala  Met Thr Leu Glu Asp  Ile Gln Thr 
    2330                 2335                 2340             


Arg Glu  Val Arg His Ile Ser  His Leu Asn Phe Thr  Ala Trp Pro 
    2345                 2350                 2355             


Asp His  Asp Thr Pro Ser Gln  Pro Asp Asp Leu Leu  Thr Phe Ile 
    2360                 2365                 2370             


Ser Tyr  Met Arg His Ile His  Arg Ser Gly Pro Ile  Ile Thr His 
    2375                 2380                 2385             


Cys Ser  Ala Gly Ile Gly Arg  Ser Gly Thr Leu Ile  Cys Ile Asp 
    2390                 2395                 2400             


Val Val  Leu Gly Leu Ile Ser  Gln Asp Leu Asp Phe  Asp Ile Ser 
    2405                 2410                 2415             


Asp Leu  Val Arg Cys Met Arg  Leu Gln Arg His Gly  Met Val Gln 
    2420                 2425                 2430             


Thr Glu  Asp Gln Tyr Ile Phe  Cys Tyr Gln Val Ile  Leu Tyr Val 
    2435                 2440                 2445             


Leu Thr  Arg Leu Gln Ala Glu  Glu Glu Gln Lys Gln  Gln Pro Gln 
    2450                 2455                 2460             


Leu Leu  Lys 
    2465     


<210>  4279
<211>  1083
<212>  PRT
<213>  homo sapiens

<400>  4279

Met Ala Cys Pro Ala Leu Gly Leu Glu Ala Leu Gln Pro Leu Gln Pro 
1               5                   10                  15      


Glu Pro Pro Pro Glu Pro Ala Phe Ser Glu Ala Gln Lys Trp Ile Glu 
            20                  25                  30          


Gln Val Thr Gly Arg Ser Phe Gly Asp Lys Asp Phe Arg Thr Gly Leu 
        35                  40                  45              


Glu Asn Gly Ile Leu Leu Cys Glu Leu Leu Asn Ala Ile Lys Pro Gly 
    50                  55                  60                  


Leu Val Lys Lys Ile Asn Arg Leu Pro Thr Pro Ile Ala Gly Leu Asp 
65                  70                  75                  80  


Asn Ile Ile Leu Phe Leu Arg Gly Cys Lys Glu Leu Gly Leu Lys Glu 
                85                  90                  95      


Ser Gln Leu Phe Asp Pro Ser Asp Leu Gln Asp Thr Ser Asn Arg Val 
            100                 105                 110         


Thr Val Lys Ser Leu Asp Tyr Ser Arg Lys Leu Lys Asn Val Leu Val 
        115                 120                 125             


Thr Ile Tyr Trp Leu Gly Lys Ala Ala Asn Ser Cys Thr Ser Tyr Ser 
    130                 135                 140                 


Gly Thr Thr Leu Asn Leu Lys Glu Phe Glu Gly Leu Leu Ala Gln Met 
145                 150                 155                 160 


Arg Lys Asp Thr Asp Asp Ile Glu Ser Pro Lys Arg Ser Ile Arg Asp 
                165                 170                 175     


Ser Gly Tyr Ile Asp Cys Trp Asp Ser Glu Arg Ser Asp Ser Leu Ser 
            180                 185                 190         


Pro Pro Arg His Gly Arg Asp Asp Ser Phe Asp Ser Leu Asp Ser Phe 
        195                 200                 205             


Gly Ser Arg Ser Arg Gln Thr Pro Ser Pro Asp Val Val Leu Arg Gly 
    210                 215                 220                 


Ser Ser Asp Gly Arg Gly Ser Asp Ser Glu Ser Asp Leu Pro His Arg 
225                 230                 235                 240 


Lys Leu Pro Asp Val Lys Lys Asp Asp Met Ser Ala Arg Arg Thr Ser 
                245                 250                 255     


His Gly Glu Pro Lys Ser Ala Val Pro Phe Asn Gln Tyr Leu Pro Asn 
            260                 265                 270         


Lys Ser Asn Gln Thr Ala Tyr Val Pro Ala Pro Leu Arg Lys Lys Lys 
        275                 280                 285             


Ala Glu Arg Glu Glu Tyr Arg Lys Ser Trp Ser Thr Ala Thr Ser Pro 
    290                 295                 300                 


Leu Gly Gly Glu Arg Pro Phe Arg Tyr Gly Pro Arg Thr Pro Val Ser 
305                 310                 315                 320 


Asp Asp Ala Glu Ser Thr Ser Met Phe Asp Met Arg Cys Glu Glu Glu 
                325                 330                 335     


Ala Ala Val Gln Pro His Ser Arg Ala Arg Gln Glu Gln Leu Gln Leu 
            340                 345                 350         


Ile Asn Asn Gln Leu Arg Glu Glu Asp Asp Lys Trp Gln Asp Asp Leu 
        355                 360                 365             


Ala Arg Trp Lys Ser Arg Arg Arg Ser Val Ser Gln Asp Leu Ile Lys 
    370                 375                 380                 


Lys Glu Glu Glu Arg Lys Lys Met Glu Lys Leu Leu Ala Gly Glu Asp 
385                 390                 395                 400 


Gly Thr Ser Glu Arg Arg Lys Ser Ile Lys Thr Tyr Arg Glu Ile Val 
                405                 410                 415     


Gln Glu Lys Glu Arg Arg Glu Arg Glu Leu His Glu Ala Tyr Lys Asn 
            420                 425                 430         


Ala Arg Ser Gln Glu Glu Ala Glu Gly Ile Leu Gln Gln Tyr Ile Glu 
        435                 440                 445             


Arg Phe Thr Ile Ser Glu Ala Val Leu Glu Arg Leu Glu Met Pro Lys 
    450                 455                 460                 


Ile Leu Glu Arg Ser His Ser Thr Glu Pro Asn Leu Ser Ser Phe Leu 
465                 470                 475                 480 


Asn Asp Pro Asn Pro Met Lys Tyr Leu Arg Gln Gln Ser Leu Pro Pro 
                485                 490                 495     


Pro Lys Phe Thr Ala Thr Val Glu Thr Thr Ile Ala Arg Ala Ser Val 
            500                 505                 510         


Leu Asp Thr Ser Met Ser Ala Gly Ser Gly Ser Pro Ser Lys Thr Val 
        515                 520                 525             


Thr Pro Lys Ala Val Pro Met Leu Thr Pro Lys Pro Tyr Ser Gln Pro 
    530                 535                 540                 


Lys Asn Ser Gln Asp Val Leu Lys Thr Phe Lys Val Asp Gly Lys Val 
545                 550                 555                 560 


Ser Val Asn Gly Glu Thr Val His Arg Glu Glu Glu Lys Glu Arg Glu 
                565                 570                 575     


Cys Pro Thr Val Ala Pro Ala His Ser Leu Thr Lys Ser Gln Met Phe 
            580                 585                 590         


Glu Gly Val Ala Arg Val His Gly Ser Pro Leu Glu Leu Lys Gln Asp 
        595                 600                 605             


Asn Gly Ser Ile Glu Ile Asn Ile Lys Lys Pro Asn Ser Val Pro Gln 
    610                 615                 620                 


Glu Leu Ala Ala Thr Thr Glu Lys Thr Glu Pro Asn Ser Gln Glu Asp 
625                 630                 635                 640 


Lys Asn Asp Gly Gly Lys Ser Arg Lys Gly Asn Ile Glu Leu Ala Ser 
                645                 650                 655     


Ser Glu Pro Gln His Phe Thr Thr Thr Val Thr Arg Cys Ser Pro Thr 
            660                 665                 670         


Val Ala Phe Val Glu Phe Pro Ser Ser Pro Gln Leu Lys Asn Asp Val 
        675                 680                 685             


Ser Glu Glu Lys Asp Gln Lys Lys Pro Glu Asn Glu Met Ser Gly Lys 
    690                 695                 700                 


Val Glu Leu Val Leu Ser Gln Lys Val Val Lys Pro Lys Ser Pro Glu 
705                 710                 715                 720 


Pro Glu Ala Thr Leu Thr Phe Pro Phe Leu Asp Lys Met Pro Glu Ala 
                725                 730                 735     


Asn Gln Leu His Leu Pro Asn Leu Asn Ser Gln Val Asp Ser Pro Ser 
            740                 745                 750         


Ser Glu Lys Ser Pro Val Met Thr Pro Gln Phe Lys Phe Trp Ala Trp 
        755                 760                 765             


Asp Pro Glu Glu Glu Arg Arg Arg Gln Glu Lys Trp Gln Gln Glu Gln 
    770                 775                 780                 


Glu Arg Leu Leu Gln Glu Arg Tyr Gln Lys Glu Gln Asp Lys Leu Lys 
785                 790                 795                 800 


Glu Glu Trp Glu Lys Ala Gln Lys Glu Val Glu Glu Glu Glu Arg Arg 
                805                 810                 815     


Tyr Tyr Glu Glu Glu Arg Lys Ile Ile Glu Asp Thr Val Val Pro Phe 
            820                 825                 830         


Thr Val Ser Ser Ser Ser Ala Asp Gln Leu Ser Thr Ser Ser Ser Met 
        835                 840                 845             


Thr Glu Gly Ser Gly Thr Met Asn Lys Ile Asp Leu Gly Asn Cys Gln 
    850                 855                 860                 


Asp Glu Lys Gln Asp Arg Arg Trp Lys Lys Ser Phe Gln Gly Asp Asp 
865                 870                 875                 880 


Ser Asp Leu Leu Leu Lys Thr Arg Glu Ser Asp Arg Leu Glu Glu Lys 
                885                 890                 895     


Gly Ser Leu Thr Glu Gly Ala Leu Ala His Ser Gly Asn Pro Val Ser 
            900                 905                 910         


Lys Gly Val His Glu Asp His Gln Leu Asp Thr Glu Ala Gly Ala Pro 
        915                 920                 925             


His Cys Gly Thr Asn Pro Gln Leu Ala Gln Asp Pro Ser Gln Asn Gln 
    930                 935                 940                 


Gln Thr Ser Asn Pro Thr His Ser Ser Glu Asp Val Lys Pro Lys Thr 
945                 950                 955                 960 


Leu Pro Leu Asp Lys Ser Ile Asn His Gln Ile Glu Ser Pro Ser Glu 
                965                 970                 975     


Arg Arg Lys Lys Ser Pro Arg Glu His Phe Gln Ala Gly Pro Phe Ser 
            980                 985                 990         


Pro Cys Ser Pro Thr Pro Pro Gly  Gln Ser Pro Asn Arg  Ser Ile Ser 
        995                 1000                 1005             


Gly Lys  Lys Leu Cys Ser Ser  Cys Gly Leu Pro Leu  Gly Lys Gly 
    1010                 1015                 1020             


Ala Ala  Met Ile Ile Glu Thr  Leu Asn Leu Tyr Phe  His Ile Gln 
    1025                 1030                 1035             


Cys Phe  Arg Cys Gly Ile Cys  Lys Gly Gln Leu Gly  Asp Ala Val 
    1040                 1045                 1050             


Ser Gly  Thr Asp Val Arg Ile  Arg Asn Gly Leu Leu  Asn Cys Asn 
    1055                 1060                 1065             


Asp Cys  Tyr Met Arg Ser Arg  Ser Ala Gly Gln Pro  Thr Thr Leu 
    1070                 1075                 1080             


<210>  4280
<211>  90
<212>  PRT
<213>  homo sapiens

<400>  4280

Met Ala Cys Pro Leu Asp Gln Ala Ile Gly Leu Leu Val Ala Ile Phe 
1               5                   10                  15      


His Lys Tyr Ser Gly Arg Glu Gly Asp Lys His Thr Leu Ser Lys Lys 
            20                  25                  30          


Glu Leu Lys Glu Leu Ile Gln Lys Glu Leu Thr Ile Gly Ser Lys Leu 
        35                  40                  45              


Gln Asp Ala Glu Ile Ala Arg Leu Met Glu Asp Leu Asp Arg Asn Lys 
    50                  55                  60                  


Asp Gln Glu Val Asn Phe Gln Glu Tyr Val Thr Phe Leu Gly Ala Leu 
65                  70                  75                  80  


Ala Leu Ile Tyr Asn Glu Ala Leu Lys Gly 
                85                  90  


<210>  4281
<211>  852
<212>  PRT
<213>  homo sapiens

<400>  4281

Met Ser Leu Phe Lys Ala Arg Asp Trp Trp Ser Thr Ile Leu Gly Asp 
1               5                   10                  15      


Lys Glu Glu Phe Asp Gln Gly Cys Leu Cys Leu Ala Asn Val Asp Asn 
            20                  25                  30          


Ser Gly Asn Gly Gln Asp Lys Ile Ile Val Gly Ser Phe Met Gly Tyr 
        35                  40                  45              


Leu Arg Ile Phe Ser Pro His Pro Ala Lys Thr Gly Asp Gly Ala Gln 
    50                  55                  60                  


Ala Glu Asp Leu Leu Leu Glu Val Asp Leu Arg Asp Pro Val Leu Gln 
65                  70                  75                  80  


Val Glu Val Gly Lys Phe Val Ser Gly Thr Glu Met Leu His Leu Ala 
                85                  90                  95      


Val Leu His Ser Arg Lys Leu Cys Val Tyr Ser Val Ser Gly Thr Leu 
            100                 105                 110         


Gly Asn Val Glu His Gly Asn Gln Cys Gln Met Lys Leu Met Tyr Glu 
        115                 120                 125             


His Asn Leu Gln Arg Thr Ala Cys Asn Met Thr Tyr Gly Ser Phe Gly 
    130                 135                 140                 


Gly Val Lys Gly Arg Asp Leu Ile Cys Ile Gln Ser Met Asp Gly Met 
145                 150                 155                 160 


Leu Met Val Phe Glu Gln Glu Ser Tyr Ala Phe Gly Arg Phe Leu Pro 
                165                 170                 175     


Gly Phe Leu Leu Pro Gly Pro Leu Ala Tyr Ser Ser Arg Thr Asp Ser 
            180                 185                 190         


Phe Leu Thr Val Ser Ser Cys Gln Gln Val Glu Ser Tyr Lys Tyr Gln 
        195                 200                 205             


Val Leu Ala Phe Ala Thr Asp Ala Asp Lys Arg Gln Glu Thr Glu Gln 
    210                 215                 220                 


Gln Lys Leu Gly Ser Gly Lys Arg Leu Val Val Asp Trp Thr Leu Asn 
225                 230                 235                 240 


Ile Gly Glu Gln Ala Leu Asp Ile Cys Ile Val Ser Phe Asn Gln Ser 
                245                 250                 255     


Ala Ser Ser Val Phe Val Leu Gly Glu Arg Asn Phe Phe Cys Leu Lys 
            260                 265                 270         


Asp Asn Gly Gln Ile Arg Phe Met Lys Lys Leu Asp Trp Ser Pro Ser 
        275                 280                 285             


Cys Phe Leu Pro Tyr Cys Ser Val Ser Glu Gly Thr Ile Asn Thr Leu 
    290                 295                 300                 


Ile Gly Asn His Asn Asn Met Leu His Ile Tyr Gln Asp Val Thr Leu 
305                 310                 315                 320 


Lys Trp Ala Thr Gln Leu Pro His Ile Pro Val Ala Val Arg Val Gly 
                325                 330                 335     


Cys Leu His Asp Leu Lys Gly Val Ile Val Thr Leu Ser Asp Asp Gly 
            340                 345                 350         


His Leu Gln Cys Ser Tyr Leu Gly Thr Asp Pro Ser Leu Phe Gln Ala 
        355                 360                 365             


Pro Asn Val Gln Ser Arg Glu Leu Asn Tyr Asp Glu Leu Asp Val Glu 
    370                 375                 380                 


Met Lys Glu Leu Gln Lys Ile Ile Lys Asp Val Asn Lys Ser Gln Gly 
385                 390                 395                 400 


Val Trp Pro Met Thr Glu Arg Glu Asp Asp Leu Asn Val Ser Val Val 
                405                 410                 415     


Val Ser Pro Asn Phe Asp Ser Val Ser Gln Ala Thr Asp Val Glu Val 
            420                 425                 430         


Gly Thr Asp Leu Val Pro Ser Val Thr Val Lys Val Thr Leu Gln Asn 
        435                 440                 445             


Arg Val Ile Leu Gln Lys Ala Lys Leu Ser Val Tyr Val Gln Pro Pro 
    450                 455                 460                 


Leu Glu Leu Thr Cys Asp Gln Phe Thr Phe Glu Phe Met Asn Arg Asn 
465                 470                 475                 480 


Pro Asp Gly Ile Pro Arg Val Ile Gln Cys Lys Phe Arg Leu Pro Leu 
                485                 490                 495     


Lys Leu Ile Cys Leu Pro Gly Gln Pro Ser Lys Thr Ala Ser His Lys 
            500                 505                 510         


Ile Thr Ile Asp Thr Asn Lys Ser Pro Val Ser Leu Leu Ser Leu Phe 
        515                 520                 525             


Pro Gly Phe Ala Ser Gln Ser Asp Asp Asp Gln Val Asn Val Met Gly 
    530                 535                 540                 


Phe His Phe Leu Gly Gly Ala Arg Ile Thr Val Leu Ala Ser Lys Thr 
545                 550                 555                 560 


Ser Gln Arg Tyr Arg Ile Gln Ser Glu Gln Phe Glu Asp Leu Trp Leu 
                565                 570                 575     


Ile Thr Asn Glu Leu Ile Leu Arg Leu Gln Glu Tyr Phe Glu Lys Gln 
            580                 585                 590         


Gly Val Lys Asp Phe Ala Cys Ser Phe Ser Gly Ser Ile Pro Leu Gln 
        595                 600                 605             


Glu Tyr Phe Glu Leu Ile Asp His His Phe Glu Leu Arg Ile Asn Gly 
    610                 615                 620                 


Glu Lys Leu Glu Glu Leu Leu Ser Glu Arg Ala Val Gln Phe Arg Ala 
625                 630                 635                 640 


Ile Gln Arg Arg Leu Leu Ala Arg Phe Lys Asp Lys Thr Pro Ala Pro 
                645                 650                 655     


Leu Gln His Leu Asp Thr Leu Leu Asp Gly Thr Tyr Lys Gln Val Ile 
            660                 665                 670         


Ala Leu Ala Asp Ala Val Glu Glu Asn Gln Gly Asn Leu Phe Gln Ser 
        675                 680                 685             


Phe Thr Arg Leu Lys Ser Ala Thr His Leu Val Ile Leu Leu Ile Ala 
    690                 695                 700                 


Leu Trp Gln Lys Leu Ser Ala Asp Gln Val Ala Ile Leu Glu Ala Ala 
705                 710                 715                 720 


Phe Leu Pro Leu Gln Glu Asp Thr Gln Glu Leu Gly Trp Glu Glu Thr 
                725                 730                 735     


Val Asp Ala Ala Ile Ser His Leu Leu Lys Thr Cys Leu Ser Lys Ser 
            740                 745                 750         


Ser Lys Glu Gln Ala Leu Asn Leu Asn Ser Gln Leu Asn Ile Pro Lys 
        755                 760                 765             


Asp Thr Ser Gln Leu Lys Lys His Ile Thr Leu Leu Cys Asp Arg Leu 
    770                 775                 780                 


Ser Lys Gly Gly Arg Leu Cys Leu Ser Thr Asp Ala Ala Ala Pro Gln 
785                 790                 795                 800 


Thr Met Val Met Pro Gly Gly Cys Thr Thr Ile Pro Glu Ser Asp Leu 
                805                 810                 815     


Glu Glu Arg Ser Val Glu Gln Asp Ser Thr Glu Leu Phe Thr Asn His 
            820                 825                 830         


Arg His Leu Thr Ala Glu Thr Pro Arg Pro Glu Val Ser Pro Leu Gln 
        835                 840                 845             


Gly Val Ser Glu 
    850         


<210>  4282
<211>  685
<212>  PRT
<213>  homo sapiens

<400>  4282

Met Asn Gln Ser Arg Ser Arg Ser Asp Gly Gly Ser Glu Glu Thr Leu 
1               5                   10                  15      


Pro Gln Asp His Asn His His Glu Asn Glu Arg Arg Trp Gln Gln Glu 
            20                  25                  30          


Arg Leu His Arg Glu Glu Ala Tyr Tyr Gln Phe Ile Asn Glu Leu Asn 
        35                  40                  45              


Asp Glu Asp Tyr Arg Leu Met Arg Asp His Asn Leu Leu Gly Thr Pro 
    50                  55                  60                  


Gly Glu Ile Thr Ser Glu Glu Leu Gln Gln Arg Leu Asp Gly Val Lys 
65                  70                  75                  80  


Glu Gln Leu Ala Ser Gln Pro Asp Leu Arg Asp Gly Thr Asn Tyr Arg 
                85                  90                  95      


Asp Ser Glu Val Pro Arg Glu Ser Ser His Glu Asp Ser Leu Leu Glu 
            100                 105                 110         


Trp Leu Asn Thr Phe Arg Arg Thr Gly Asn Ala Thr Arg Ser Gly Gln 
        115                 120                 125             


Asn Gly Asn Gln Thr Trp Arg Ala Val Ser Arg Thr Asn Pro Asn Asn 
    130                 135                 140                 


Gly Glu Phe Arg Phe Ser Leu Glu Ile His Val Asn His Glu Asn Arg 
145                 150                 155                 160 


Gly Phe Glu Ile His Gly Glu Asp Tyr Thr Asp Ile Pro Leu Ser Asp 
                165                 170                 175     


Ser Asn Arg Asp His Thr Ala Asn Arg Gln Gln Arg Ser Thr Ser Pro 
            180                 185                 190         


Val Ala Arg Arg Thr Arg Ser Gln Thr Ser Val Asn Phe Asn Gly Ser 
        195                 200                 205             


Ser Ser Asn Ile Pro Arg Thr Arg Leu Ala Ser Arg Gly Gln Asn Pro 
    210                 215                 220                 


Ala Glu Gly Ser Phe Ser Thr Leu Gly Arg Leu Arg Asn Gly Ile Gly 
225                 230                 235                 240 


Gly Ala Ala Gly Ile Pro Arg Ala Asn Ala Ser Arg Thr Asn Phe Ser 
                245                 250                 255     


Ser His Thr Asn Gln Ser Gly Gly Ser Glu Leu Arg Gln Arg Glu Gly 
            260                 265                 270         


Gln Arg Phe Gly Ala Ala His Val Trp Glu Asn Gly Ala Arg Ser Asn 
        275                 280                 285             


Val Thr Val Arg Asn Thr Asn Gln Arg Leu Glu Pro Ile Arg Leu Arg 
    290                 295                 300                 


Ser Thr Ser Asn Ser Arg Ser Arg Ser Pro Ile Gln Arg Gln Ser Gly 
305                 310                 315                 320 


Thr Val Tyr His Asn Ser Gln Arg Glu Ser Arg Pro Val Gln Gln Thr 
                325                 330                 335     


Thr Arg Arg Ser Val Arg Arg Arg Gly Arg Thr Arg Val Phe Leu Glu 
            340                 345                 350         


Gln Asp Arg Glu Arg Glu Arg Arg Gly Thr Ala Tyr Thr Pro Phe Ser 
        355                 360                 365             


Asn Ser Arg Leu Val Ser Arg Ile Thr Val Glu Glu Gly Glu Glu Ser 
    370                 375                 380                 


Ser Arg Ser Ser Thr Ala Val Arg Arg His Pro Thr Ile Thr Leu Asp 
385                 390                 395                 400 


Leu Gln Val Arg Arg Ile Arg Pro Gly Glu Asn Arg Asp Arg Asp Ser 
                405                 410                 415     


Ile Ala Asn Arg Thr Arg Ser Arg Val Gly Leu Ala Glu Asn Thr Val 
            420                 425                 430         


Thr Ile Glu Ser Asn Ser Gly Gly Phe Arg Arg Thr Ile Ser Arg Leu 
        435                 440                 445             


Glu Arg Ser Gly Ile Arg Thr Tyr Val Ser Thr Ile Thr Val Pro Leu 
    450                 455                 460                 


Arg Arg Ile Ser Glu Asn Glu Leu Val Glu Pro Ser Ser Val Ala Leu 
465                 470                 475                 480 


Arg Ser Ile Leu Arg Gln Ile Met Thr Gly Phe Gly Glu Leu Ser Ser 
                485                 490                 495     


Leu Met Glu Ala Asp Ser Glu Ser Glu Leu Gln Arg Asn Gly Gln His 
            500                 505                 510         


Leu Pro Asp Met His Ser Glu Leu Ser Asn Leu Gly Thr Asp Asn Asn 
        515                 520                 525             


Arg Ser Gln His Arg Glu Gly Ser Ser Gln Asp Arg Gln Ala Gln Gly 
    530                 535                 540                 


Asp Ser Thr Glu Met His Gly Glu Asn Glu Thr Thr Gln Pro His Thr 
545                 550                 555                 560 


Arg Asn Ser Asp Ser Arg Gly Gly Arg Gln Leu Arg Asn Pro Asn Asn 
                565                 570                 575     


Leu Val Glu Thr Gly Thr Leu Pro Ile Leu Arg Leu Ala His Phe Phe 
            580                 585                 590         


Leu Leu Asn Glu Ser Asp Asp Asp Asp Arg Ile Arg Gly Leu Thr Lys 
        595                 600                 605             


Glu Gln Ile Asp Asn Leu Ser Thr Arg His Tyr Glu His Asn Ser Ile 
    610                 615                 620                 


Asp Ser Glu Leu Gly Lys Ile Cys Ser Val Cys Ile Ser Asp Tyr Val 
625                 630                 635                 640 


Thr Gly Asn Lys Leu Arg Gln Leu Pro Cys Met His Glu Phe His Ile 
                645                 650                 655     


His Cys Ile Asp Arg Trp Leu Ser Glu Asn Cys Thr Cys Pro Ile Cys 
            660                 665                 670         


Arg Gln Pro Val Leu Gly Ser Asn Ile Ala Asn Asn Gly 
        675                 680                 685 


<210>  4283
<211>  725
<212>  PRT
<213>  homo sapiens

<400>  4283

Met Ala Met Asp Ser Ser Leu Gln Ala Arg Leu Phe Pro Gly Leu Ala 
1               5                   10                  15      


Ile Lys Ile Gln Arg Ser Asn Gly Leu Ile His Ser Ala Asn Val Arg 
            20                  25                  30          


Thr Val Asn Leu Glu Lys Ser Cys Val Ser Val Glu Trp Ala Glu Gly 
        35                  40                  45              


Gly Ala Thr Lys Gly Lys Glu Ile Asp Phe Asp Asp Val Ala Ala Ile 
    50                  55                  60                  


Asn Pro Glu Leu Leu Gln Leu Leu Pro Leu His Pro Lys Asp Asn Leu 
65                  70                  75                  80  


Pro Leu Gln Glu Asn Val Thr Ile Gln Lys Gln Lys Arg Arg Ser Val 
                85                  90                  95      


Asn Ser Lys Ile Pro Ala Pro Lys Glu Ser Leu Arg Ser Arg Ser Thr 
            100                 105                 110         


Arg Met Ser Thr Val Ser Glu Leu Arg Ile Thr Ala Gln Glu Asn Asp 
        115                 120                 125             


Met Glu Val Glu Leu Pro Ala Ala Ala Asn Ser Arg Lys Gln Phe Ser 
    130                 135                 140                 


Val Pro Pro Ala Pro Thr Arg Pro Ser Cys Pro Ala Val Ala Glu Ile 
145                 150                 155                 160 


Pro Leu Arg Met Val Ser Glu Glu Met Glu Glu Gln Val His Ser Ile 
                165                 170                 175     


Arg Gly Ser Ser Ser Ala Asn Pro Val Asn Ser Val Arg Arg Lys Ser 
            180                 185                 190         


Cys Leu Val Lys Glu Val Glu Lys Met Lys Asn Lys Arg Glu Glu Lys 
        195                 200                 205             


Lys Ala Gln Asn Ser Glu Met Arg Met Lys Arg Ala Gln Glu Tyr Asp 
    210                 215                 220                 


Ser Ser Phe Pro Asn Trp Glu Phe Ala Arg Met Ile Lys Glu Phe Arg 
225                 230                 235                 240 


Ala Thr Leu Glu Cys His Pro Leu Thr Met Thr Asp Pro Ile Glu Glu 
                245                 250                 255     


His Arg Ile Cys Val Cys Val Arg Lys Arg Pro Leu Asn Lys Gln Glu 
            260                 265                 270         


Leu Ala Lys Lys Glu Ile Asp Val Ile Ser Ile Pro Ser Lys Cys Leu 
        275                 280                 285             


Leu Leu Val His Glu Pro Lys Leu Lys Val Asp Leu Thr Lys Tyr Leu 
    290                 295                 300                 


Glu Asn Gln Ala Phe Cys Phe Asp Phe Ala Phe Asp Glu Thr Ala Ser 
305                 310                 315                 320 


Asn Glu Val Val Tyr Arg Phe Thr Ala Arg Pro Leu Val Gln Thr Ile 
                325                 330                 335     


Phe Glu Gly Gly Lys Ala Thr Cys Phe Ala Tyr Gly Gln Thr Gly Ser 
            340                 345                 350         


Gly Lys Thr His Thr Met Gly Gly Asp Leu Ser Gly Lys Ala Gln Asn 
        355                 360                 365             


Ala Ser Lys Gly Ile Tyr Ala Met Ala Ser Arg Asp Val Phe Leu Leu 
    370                 375                 380                 


Lys Asn Gln Pro Cys Tyr Arg Lys Leu Gly Leu Glu Val Tyr Val Thr 
385                 390                 395                 400 


Phe Phe Glu Ile Tyr Asn Gly Lys Leu Phe Asp Leu Leu Asn Lys Lys 
                405                 410                 415     


Ala Lys Leu Arg Val Leu Glu Asp Gly Lys Gln Gln Val Gln Val Val 
            420                 425                 430         


Gly Leu Gln Glu His Leu Val Asn Ser Ala Asp Asp Val Ile Lys Met 
        435                 440                 445             


Ile Asp Met Gly Ser Ala Cys Arg Thr Ser Gly Gln Thr Phe Ala Asn 
    450                 455                 460                 


Ser Asn Ser Ser Arg Ser His Ala Cys Phe Gln Ile Ile Leu Arg Ala 
465                 470                 475                 480 


Lys Gly Arg Met His Gly Lys Phe Ser Leu Val Asp Leu Ala Gly Asn 
                485                 490                 495     


Glu Arg Gly Ala Asp Thr Ser Ser Ala Asp Arg Gln Thr Arg Met Glu 
            500                 505                 510         


Gly Ala Glu Ile Asn Lys Ser Leu Leu Ala Leu Lys Glu Cys Ile Arg 
        515                 520                 525             


Ala Leu Gly Gln Asn Lys Ala His Thr Pro Phe Arg Glu Ser Lys Leu 
    530                 535                 540                 


Thr Gln Val Leu Arg Asp Ser Phe Ile Gly Glu Asn Ser Arg Thr Cys 
545                 550                 555                 560 


Met Ile Ala Thr Ile Ser Pro Gly Ile Ser Ser Cys Glu Tyr Thr Leu 
                565                 570                 575     


Asn Thr Leu Arg Tyr Ala Asp Arg Val Lys Glu Leu Ser Pro His Ser 
            580                 585                 590         


Gly Pro Ser Gly Glu Gln Leu Ile Gln Met Glu Thr Glu Glu Met Glu 
        595                 600                 605             


Ala Cys Ser Asn Gly Ala Leu Ile Pro Gly Asn Leu Ser Lys Glu Glu 
    610                 615                 620                 


Glu Glu Leu Ser Ser Gln Met Ser Ser Phe Asn Glu Ala Met Thr Gln 
625                 630                 635                 640 


Ile Arg Glu Leu Glu Glu Lys Ala Met Glu Glu Leu Lys Glu Ile Ile 
                645                 650                 655     


Gln Gln Gly Pro Asp Trp Leu Glu Leu Ser Glu Met Thr Glu Gln Pro 
            660                 665                 670         


Asp Tyr Asp Leu Glu Thr Phe Val Asn Lys Ala Glu Ser Ala Leu Ala 
        675                 680                 685             


Gln Gln Ala Lys His Phe Ser Ala Leu Arg Asp Val Ile Lys Ala Leu 
    690                 695                 700                 


Arg Leu Ala Met Gln Leu Glu Glu Gln Ala Ser Arg Gln Ile Ser Ser 
705                 710                 715                 720 


Lys Lys Arg Pro Gln 
                725 


<210>  4284
<211>  699
<212>  PRT
<213>  homo sapiens

<400>  4284

Met Pro Ile Asn Lys Ser Glu Lys Pro Glu Ser Cys Asp Asn Val Lys 
1               5                   10                  15      


Val Val Val Arg Cys Arg Pro Leu Asn Glu Arg Glu Lys Ser Met Cys 
            20                  25                  30          


Tyr Lys Gln Ala Val Ser Val Asp Glu Met Arg Gly Thr Ile Thr Val 
        35                  40                  45              


His Lys Thr Asp Ser Ser Asn Glu Pro Pro Lys Thr Phe Thr Phe Asp 
    50                  55                  60                  


Thr Val Phe Gly Pro Glu Ser Lys Gln Leu Asp Val Tyr Asn Leu Thr 
65                  70                  75                  80  


Ala Arg Pro Ile Ile Asp Ser Val Leu Glu Gly Tyr Asn Gly Thr Ile 
                85                  90                  95      


Phe Ala Tyr Gly Gln Thr Gly Thr Gly Lys Thr Phe Thr Met Glu Gly 
            100                 105                 110         


Val Arg Ala Ile Pro Glu Leu Arg Gly Ile Ile Pro Asn Ser Phe Ala 
        115                 120                 125             


His Ile Phe Gly His Ile Ala Lys Ala Glu Gly Asp Thr Arg Phe Leu 
    130                 135                 140                 


Val Arg Val Ser Tyr Leu Glu Ile Tyr Asn Glu Glu Val Arg Asp Leu 
145                 150                 155                 160 


Leu Gly Lys Asp Gln Thr Gln Arg Leu Glu Val Lys Glu Arg Pro Asp 
                165                 170                 175     


Val Gly Val Tyr Ile Lys Asp Leu Ser Ala Tyr Val Val Asn Asn Ala 
            180                 185                 190         


Asp Asp Met Asp Arg Ile Met Thr Leu Gly His Lys Asn Arg Ser Val 
        195                 200                 205             


Gly Ala Thr Asn Met Asn Glu His Ser Ser Arg Ser His Ala Ile Phe 
    210                 215                 220                 


Thr Ile Thr Ile Glu Cys Ser Glu Lys Gly Ile Asp Gly Asn Met His 
225                 230                 235                 240 


Val Arg Met Gly Lys Leu His Leu Val Asp Leu Ala Gly Ser Glu Arg 
                245                 250                 255     


Gln Ala Lys Thr Gly Ala Thr Gly Gln Arg Leu Lys Glu Ala Thr Lys 
            260                 265                 270         


Ile Asn Leu Ser Leu Ser Thr Leu Gly Asn Val Ile Ser Ala Leu Val 
        275                 280                 285             


Asp Gly Lys Ser Thr His Val Pro Tyr Arg Asn Ser Lys Leu Thr Arg 
    290                 295                 300                 


Leu Leu Gln Asp Ser Leu Gly Gly Asn Ser Lys Thr Met Met Cys Ala 
305                 310                 315                 320 


Asn Ile Gly Pro Ala Asp Tyr Asn Tyr Asp Glu Thr Ile Ser Thr Leu 
                325                 330                 335     


Arg Tyr Ala Asn Arg Ala Lys Asn Ile Lys Asn Lys Ala Arg Ile Asn 
            340                 345                 350         


Glu Asp Pro Lys Asp Ala Leu Leu Arg Gln Phe Gln Lys Glu Ile Glu 
        355                 360                 365             


Glu Leu Lys Lys Lys Leu Glu Glu Gly Glu Glu Ile Ser Gly Ser Asp 
    370                 375                 380                 


Ile Ser Gly Ser Glu Glu Asp Asp Asp Glu Glu Gly Glu Val Gly Glu 
385                 390                 395                 400 


Asp Gly Glu Lys Arg Lys Lys Arg Arg Gly Lys Lys Lys Val Ser Pro 
                405                 410                 415     


Asp Lys Met Ile Glu Met Gln Ala Lys Ile Asp Glu Glu Arg Lys Ala 
            420                 425                 430         


Leu Glu Thr Lys Leu Asp Met Glu Glu Glu Glu Arg Asn Lys Ala Arg 
        435                 440                 445             


Ala Glu Leu Glu Lys Arg Glu Lys Asp Leu Leu Lys Ala Gln Gln Glu 
    450                 455                 460                 


His Gln Ser Leu Leu Glu Lys Leu Ser Ala Leu Glu Lys Lys Val Ile 
465                 470                 475                 480 


Val Gly Gly Val Asp Leu Leu Ala Lys Ala Glu Glu Gln Glu Lys Leu 
                485                 490                 495     


Leu Glu Glu Ser Asn Met Glu Leu Glu Glu Arg Arg Lys Arg Ala Glu 
            500                 505                 510         


Gln Leu Arg Arg Glu Leu Glu Glu Lys Glu Gln Glu Arg Leu Asp Ile 
        515                 520                 525             


Glu Glu Lys Tyr Thr Ser Leu Gln Glu Glu Ala Gln Gly Lys Thr Lys 
    530                 535                 540                 


Lys Leu Lys Lys Val Trp Thr Met Leu Met Ala Ala Lys Ser Glu Met 
545                 550                 555                 560 


Ala Asp Leu Gln Gln Glu His Gln Arg Glu Ile Glu Gly Leu Leu Glu 
                565                 570                 575     


Asn Ile Arg Gln Leu Ser Arg Glu Leu Arg Leu Gln Met Leu Ile Ile 
            580                 585                 590         


Asp Asn Phe Ile Pro Arg Asp Tyr Gln Glu Met Ile Glu Asn Tyr Val 
        595                 600                 605             


His Trp Asn Glu Asp Ile Gly Glu Trp Gln Leu Lys Cys Val Ala Tyr 
    610                 615                 620                 


Thr Gly Asn Asn Met Arg Lys Gln Thr Pro Val Pro Asp Lys Lys Glu 
625                 630                 635                 640 


Lys Asp Pro Phe Glu Val Asp Leu Ser His Val Tyr Leu Ala Tyr Thr 
                645                 650                 655     


Glu Glu Ser Leu Arg Gln Ser Leu Met Lys Leu Glu Arg Pro Arg Thr 
            660                 665                 670         


Ser Lys Gly Lys Ala Arg Pro Lys Thr Gly Arg Arg Lys Arg Ser Ala 
        675                 680                 685             


Lys Pro Glu Thr Val Ile Asp Ser Leu Leu Gln 
    690                 695                 


<210>  4285
<211>  480
<212>  PRT
<213>  homo sapiens

<400>  4285

Met Leu Asn Phe Gly Ala Ser Leu Gln Gln Thr Ala Glu Glu Arg Met 
1               5                   10                  15      


Glu Met Ile Ser Glu Arg Pro Lys Glu Ser Met Tyr Ser Trp Asn Lys 
            20                  25                  30          


Thr Ala Glu Lys Ser Asp Phe Glu Ala Val Glu Ala Leu Met Ser Met 
        35                  40                  45              


Ser Cys Ser Trp Lys Ser Asp Phe Lys Lys Tyr Val Glu Asn Arg Pro 
    50                  55                  60                  


Val Thr Pro Val Ser Asp Leu Ser Glu Glu Glu Asn Leu Leu Pro Gly 
65                  70                  75                  80  


Thr Pro Asp Phe His Thr Ile Pro Ala Phe Cys Leu Thr Pro Pro Tyr 
                85                  90                  95      


Ser Pro Ser Asp Phe Glu Pro Ser Gln Val Ser Asn Leu Met Ala Pro 
            100                 105                 110         


Ala Pro Ser Thr Val His Phe Lys Ser Leu Ser Asp Thr Ala Lys Pro 
        115                 120                 125             


His Ile Ala Ala Pro Phe Lys Glu Glu Glu Lys Ser Pro Val Ser Ala 
    130                 135                 140                 


Pro Lys Leu Pro Lys Ala Gln Ala Thr Ser Val Ile Arg His Thr Ala 
145                 150                 155                 160 


Asp Ala Gln Leu Cys Asn His Gln Thr Cys Pro Met Lys Ala Ala Ser 
                165                 170                 175     


Ile Leu Asn Tyr Gln Asn Asn Ser Phe Arg Arg Arg Thr His Leu Asn 
            180                 185                 190         


Val Glu Ala Ala Arg Lys Asn Ile Pro Cys Ala Ala Val Ser Pro Asn 
        195                 200                 205             


Arg Ser Lys Cys Glu Arg Asn Thr Val Ala Asp Val Asp Glu Lys Ala 
    210                 215                 220                 


Ser Ala Ala Leu Tyr Asp Phe Ser Val Pro Ser Ser Glu Thr Val Ile 
225                 230                 235                 240 


Cys Arg Ser Gln Pro Ala Pro Val Ser Pro Gln Gln Lys Ser Val Leu 
                245                 250                 255     


Val Ser Pro Pro Ala Val Ser Ala Gly Gly Val Pro Pro Met Pro Val 
            260                 265                 270         


Ile Cys Gln Met Val Pro Leu Pro Ala Asn Asn Pro Val Val Thr Thr 
        275                 280                 285             


Val Val Pro Ser Thr Pro Pro Ser Gln Pro Pro Ala Val Cys Pro Pro 
    290                 295                 300                 


Val Val Phe Met Gly Thr Gln Val Pro Lys Gly Ala Val Met Phe Val 
305                 310                 315                 320 


Val Pro Gln Pro Val Val Gln Ser Ser Lys Pro Pro Val Val Ser Pro 
                325                 330                 335     


Asn Gly Thr Arg Leu Ser Pro Ile Ala Pro Ala Pro Gly Phe Ser Pro 
            340                 345                 350         


Ser Ala Ala Lys Val Thr Pro Gln Ile Asp Ser Ser Arg Ile Arg Ser 
        355                 360                 365             


His Ile Cys Ser His Pro Gly Cys Gly Lys Thr Tyr Phe Lys Ser Ser 
    370                 375                 380                 


His Leu Lys Ala His Thr Arg Thr His Thr Gly Glu Lys Pro Phe Ser 
385                 390                 395                 400 


Cys Ser Trp Lys Gly Cys Glu Arg Arg Phe Ala Arg Ser Asp Glu Leu 
                405                 410                 415     


Ser Arg His Arg Arg Thr His Thr Gly Glu Lys Lys Phe Ala Cys Pro 
            420                 425                 430         


Met Cys Asp Arg Arg Phe Met Arg Ser Asp His Leu Thr Lys His Ala 
        435                 440                 445             


Arg Arg His Leu Ser Ala Lys Lys Leu Pro Asn Trp Gln Met Glu Val 
    450                 455                 460                 


Ser Lys Leu Asn Asp Ile Ala Leu Pro Pro Thr Pro Ala Pro Thr Gln 
465                 470                 475                 480 


<210>  4286
<211>  523
<212>  PRT
<213>  homo sapiens

<400>  4286

Met Met Leu Arg Gly Asn Leu Lys Gln Val Arg Ile Glu Lys Asn Pro 
1               5                   10                  15      


Ala Arg Leu Arg Ala Leu Glu Ser Ala Val Gly Glu Ser Glu Pro Ala 
            20                  25                  30          


Ala Ala Ala Ala Met Ala Leu Ala Leu Ala Gly Glu Pro Ala Pro Pro 
        35                  40                  45              


Ala Pro Ala Pro Pro Glu Asp His Pro Asp Glu Glu Met Gly Phe Thr 
    50                  55                  60                  


Ile Asp Ile Lys Ser Phe Leu Lys Pro Gly Glu Lys Thr Tyr Thr Gln 
65                  70                  75                  80  


Arg Cys Arg Leu Phe Val Gly Asn Leu Pro Thr Asp Ile Thr Glu Glu 
                85                  90                  95      


Asp Phe Lys Arg Leu Phe Glu Arg Tyr Gly Glu Pro Ser Glu Val Phe 
            100                 105                 110         


Ile Asn Arg Asp Arg Gly Phe Gly Phe Ile Arg Leu Glu Ser Arg Thr 
        115                 120                 125             


Leu Ala Glu Ile Ala Lys Ala Glu Leu Asp Gly Thr Ile Leu Lys Ser 
    130                 135                 140                 


Arg Pro Leu Arg Ile Arg Phe Ala Thr His Gly Ala Ala Leu Thr Val 
145                 150                 155                 160 


Lys Asn Leu Ser Pro Val Val Ser Asn Glu Leu Leu Glu Gln Ala Phe 
                165                 170                 175     


Ser Gln Phe Gly Pro Val Glu Lys Ala Val Val Val Val Asp Asp Arg 
            180                 185                 190         


Gly Arg Ala Thr Gly Lys Gly Phe Val Glu Phe Ala Ala Lys Pro Pro 
        195                 200                 205             


Ala Arg Lys Ala Leu Glu Arg Cys Gly Asp Gly Ala Phe Leu Leu Thr 
    210                 215                 220                 


Thr Thr Pro Arg Pro Val Ile Val Glu Pro Met Glu Gln Phe Asp Asp 
225                 230                 235                 240 


Glu Asp Gly Leu Pro Glu Lys Leu Met Gln Lys Thr Gln Gln Tyr His 
                245                 250                 255     


Lys Glu Arg Glu Gln Pro Pro Arg Phe Ala Gln Pro Gly Thr Phe Glu 
            260                 265                 270         


Phe Glu Tyr Ala Ser Arg Trp Lys Ala Leu Asp Glu Met Glu Lys Gln 
        275                 280                 285             


Gln Arg Glu Gln Val Asp Arg Asn Ile Arg Glu Ala Lys Glu Lys Leu 
    290                 295                 300                 


Glu Ala Glu Met Glu Ala Ala Arg His Glu His Gln Leu Met Leu Met 
305                 310                 315                 320 


Arg Gln Asp Leu Met Arg Arg Gln Glu Glu Leu Arg Arg Leu Glu Glu 
                325                 330                 335     


Leu Arg Asn Gln Glu Leu Gln Lys Arg Lys Gln Ile Gln Leu Arg His 
            340                 345                 350         


Glu Glu Glu His Arg Arg Arg Glu Glu Glu Met Ile Arg His Arg Glu 
        355                 360                 365             


Gln Glu Glu Leu Arg Arg Gln Gln Glu Gly Phe Lys Pro Asn Tyr Met 
    370                 375                 380                 


Glu Asn Arg Glu Gln Glu Met Arg Met Gly Asp Met Gly Pro Arg Gly 
385                 390                 395                 400 


Ala Ile Asn Met Gly Asp Ala Phe Ser Pro Ala Pro Ala Gly Asn Gln 
                405                 410                 415     


Gly Pro Pro Pro Met Met Gly Met Asn Met Asn Asn Arg Ala Thr Ile 
            420                 425                 430         


Pro Gly Pro Pro Met Gly Pro Gly Pro Ala Met Gly Pro Glu Gly Ala 
        435                 440                 445             


Ala Asn Met Gly Thr Pro Met Met Pro Asp Asn Gly Ala Val His Asn 
    450                 455                 460                 


Asp Arg Phe Pro Gln Gly Pro Pro Ser Gln Met Gly Ser Pro Met Gly 
465                 470                 475                 480 


Ser Arg Thr Gly Ser Glu Thr Pro Gln Ala Pro Met Ser Gly Val Gly 
                485                 490                 495     


Pro Val Ser Gly Gly Pro Gly Gly Phe Gly Arg Gly Ser Gln Gly Gly 
            500                 505                 510         


Asn Phe Glu Gly Pro Asn Lys Arg Arg Arg Tyr 
        515                 520             


<210>  4287
<211>  484
<212>  PRT
<213>  homo sapiens

<400>  4287

Met Glu Arg Arg Met Lys Ala Gly Tyr Leu Asp Gln Gln Val Pro Tyr 
1               5                   10                  15      


Thr Phe Ser Ser Lys Ser Pro Gly Asn Gly Ser Leu Arg Glu Ala Leu 
            20                  25                  30          


Ile Gly Pro Leu Gly Lys Leu Met Asp Pro Gly Ser Leu Pro Pro Leu 
        35                  40                  45              


Asp Ser Glu Asp Leu Phe Gln Asp Leu Ser His Phe Gln Glu Thr Trp 
    50                  55                  60                  


Leu Ala Glu Ala Gln Val Pro Asp Ser Asp Glu Gln Phe Val Pro Asp 
65                  70                  75                  80  


Phe His Ser Glu Asn Leu Ala Phe His Ser Pro Thr Thr Arg Ile Lys 
                85                  90                  95      


Lys Glu Pro Gln Ser Pro Arg Thr Asp Pro Ala Leu Ser Cys Ser Arg 
            100                 105                 110         


Lys Pro Pro Leu Pro Tyr His His Gly Glu Gln Cys Leu Tyr Ser Ser 
        115                 120                 125             


Ala Tyr Asp Pro Pro Arg Gln Ile Ala Ile Lys Ser Pro Ala Pro Gly 
    130                 135                 140                 


Ala Leu Gly Gln Ser Pro Leu Gln Pro Phe Pro Arg Ala Glu Gln Arg 
145                 150                 155                 160 


Asn Phe Leu Arg Ser Ser Gly Thr Ser Gln Pro His Pro Gly His Gly 
                165                 170                 175     


Tyr Leu Gly Glu His Ser Ser Val Phe Gln Gln Pro Leu Asp Ile Cys 
            180                 185                 190         


His Ser Phe Thr Ser Gln Gly Gly Gly Arg Glu Pro Leu Pro Ala Pro 
        195                 200                 205             


Tyr Gln His Gln Leu Ser Glu Pro Cys Pro Pro Tyr Pro Gln Gln Ser 
    210                 215                 220                 


Phe Lys Gln Glu Tyr His Asp Pro Leu Tyr Glu Gln Ala Gly Gln Pro 
225                 230                 235                 240 


Ala Val Asp Gln Gly Gly Val Asn Gly His Arg Tyr Pro Gly Ala Gly 
                245                 250                 255     


Val Val Ile Lys Gln Glu Gln Thr Asp Phe Ala Tyr Asp Ser Asp Val 
            260                 265                 270         


Thr Gly Cys Ala Ser Met Tyr Leu His Thr Glu Gly Phe Ser Gly Pro 
        275                 280                 285             


Ser Pro Gly Asp Gly Ala Met Gly Tyr Gly Tyr Glu Lys Pro Leu Arg 
    290                 295                 300                 


Pro Phe Pro Asp Asp Val Cys Val Val Pro Glu Lys Phe Glu Gly Asp 
305                 310                 315                 320 


Ile Lys Gln Glu Gly Val Gly Ala Phe Arg Glu Gly Pro Pro Tyr Gln 
                325                 330                 335     


Arg Arg Gly Ala Leu Gln Leu Trp Gln Phe Leu Val Ala Leu Leu Asp 
            340                 345                 350         


Asp Pro Thr Asn Ala His Phe Ile Ala Trp Thr Gly Arg Gly Met Glu 
        355                 360                 365             


Phe Lys Leu Ile Glu Pro Glu Glu Val Ala Arg Leu Trp Gly Ile Gln 
    370                 375                 380                 


Lys Asn Arg Pro Ala Met Asn Tyr Asp Lys Leu Ser Arg Ser Leu Arg 
385                 390                 395                 400 


Tyr Tyr Tyr Glu Lys Gly Ile Met Gln Lys Val Ala Gly Glu Arg Tyr 
                405                 410                 415     


Val Tyr Lys Phe Val Cys Glu Pro Glu Ala Leu Phe Ser Leu Ala Phe 
            420                 425                 430         


Pro Asp Asn Gln Arg Pro Ala Leu Lys Ala Glu Phe Asp Arg Pro Val 
        435                 440                 445             


Ser Glu Glu Asp Thr Val Pro Leu Ser His Leu Asp Glu Ser Pro Ala 
    450                 455                 460                 


Tyr Leu Pro Glu Leu Ala Gly Pro Ala Gln Pro Phe Gly Pro Lys Gly 
465                 470                 475                 480 


Gly Tyr Ser Tyr 
                


<210>  4288
<211>  441
<212>  PRT
<213>  homo sapiens

<400>  4288

Met Ile Ile Pro Ser Leu Glu Glu Leu Asp Ser Leu Lys Tyr Ser Asp 
1               5                   10                  15      


Leu Gln Asn Leu Ala Lys Ser Leu Gly Leu Arg Ala Asn Leu Arg Ala 
            20                  25                  30          


Thr Lys Leu Leu Lys Ala Leu Lys Gly Tyr Ile Lys His Glu Ala Arg 
        35                  40                  45              


Lys Gly Asn Glu Asn Gln Asp Glu Ser Gln Thr Ser Ala Ser Ser Cys 
    50                  55                  60                  


Asp Glu Thr Glu Ile Gln Ile Ser Asn Gln Glu Glu Ala Glu Arg Gln 
65                  70                  75                  80  


Pro Leu Gly His Val Thr Lys Thr Arg Arg Arg Cys Lys Thr Val Arg 
                85                  90                  95      


Val Asp Pro Asp Ser Gln Gln Asn His Ser Glu Ile Lys Ile Ser Asn 
            100                 105                 110         


Pro Thr Glu Phe Gln Asn His Glu Lys Gln Glu Ser Gln Asp Leu Arg 
        115                 120                 125             


Ala Thr Ala Lys Val Pro Ser Pro Pro Asp Glu His Gln Glu Ala Glu 
    130                 135                 140                 


Asn Ala Val Ser Ser Gly Asn Arg Asp Ser Lys Val Pro Ser Glu Gly 
145                 150                 155                 160 


Lys Lys Ser Leu Tyr Thr Asp Glu Ser Ser Lys Pro Gly Lys Asn Lys 
                165                 170                 175     


Arg Thr Ala Ile Thr Thr Pro Asn Phe Lys Lys Leu His Glu Ala His 
            180                 185                 190         


Phe Lys Glu Met Glu Ser Ile Asp Gln Tyr Ile Glu Arg Lys Lys Lys 
        195                 200                 205             


His Phe Glu Glu His Asn Ser Met Asn Glu Leu Lys Gln Gln Pro Ile 
    210                 215                 220                 


Asn Lys Gly Gly Val Arg Thr Pro Val Pro Pro Arg Gly Arg Leu Ser 
225                 230                 235                 240 


Val Ala Ser Thr Pro Ile Ser Gln Arg Arg Ser Gln Gly Arg Ser Cys 
                245                 250                 255     


Gly Pro Ala Ser Gln Ser Thr Leu Gly Leu Lys Gly Ser Leu Lys Arg 
            260                 265                 270         


Ser Ala Ile Ser Ala Ala Lys Thr Gly Val Arg Phe Ser Ala Ala Thr 
        275                 280                 285             


Lys Asp Asn Glu His Lys Arg Ser Leu Thr Lys Thr Pro Ala Arg Lys 
    290                 295                 300                 


Ser Ala His Val Thr Val Ser Gly Gly Thr Pro Lys Gly Glu Ala Val 
305                 310                 315                 320 


Leu Gly Thr His Lys Leu Lys Thr Ile Thr Gly Asn Ser Ala Ala Val 
                325                 330                 335     


Ile Thr Pro Phe Lys Leu Thr Thr Glu Ala Thr Gln Thr Pro Val Ser 
            340                 345                 350         


Asn Lys Lys Pro Val Phe Asp Leu Lys Ala Ser Leu Ser Arg Pro Leu 
        355                 360                 365             


Asn Tyr Glu Pro His Lys Gly Lys Leu Lys Pro Trp Gly Gln Ser Lys 
    370                 375                 380                 


Glu Asn Asn Tyr Leu Asn Gln His Val Asn Arg Ile Asn Phe Tyr Lys 
385                 390                 395                 400 


Lys Thr Tyr Lys Gln Pro His Leu Gln Thr Lys Glu Glu Gln Arg Lys 
                405                 410                 415     


Lys Arg Glu Gln Glu Arg Lys Glu Lys Lys Ala Lys Val Leu Gly Met 
            420                 425                 430         


Arg Arg Gly Leu Ile Leu Ala Glu Asp 
        435                 440     


<210>  4289
<211>  638
<212>  PRT
<213>  homo sapiens

<400>  4289

Met Ser Asp Lys Ser Glu Leu Lys Ala Glu Leu Glu Arg Lys Lys Gln 
1               5                   10                  15      


Arg Leu Ala Gln Ile Arg Glu Glu Lys Lys Arg Lys Glu Glu Glu Arg 
            20                  25                  30          


Lys Lys Lys Glu Thr Asp Gln Lys Lys Glu Ala Val Ala Pro Val Gln 
        35                  40                  45              


Glu Glu Ser Asp Leu Glu Lys Lys Arg Arg Glu Ala Glu Ala Leu Leu 
    50                  55                  60                  


Gln Ser Met Gly Leu Thr Pro Glu Ser Pro Ile Val Phe Ser Glu Tyr 
65                  70                  75                  80  


Trp Val Pro Pro Pro Met Ser Pro Ser Ser Lys Ser Val Ser Thr Pro 
                85                  90                  95      


Ser Glu Ala Gly Ser Gln Asp Ser Gly Asp Gly Ala Val Gly Ser Arg 
            100                 105                 110         


Thr Leu His Trp Asp Thr Asp Pro Ser Val Leu Gln Leu His Ser Asp 
        115                 120                 125             


Ser Asp Leu Gly Arg Gly Pro Ile Lys Leu Gly Met Ala Lys Ile Thr 
    130                 135                 140                 


Gln Val Asp Phe Pro Pro Arg Glu Ile Val Thr Tyr Thr Lys Glu Thr 
145                 150                 155                 160 


Gln Thr Pro Val Met Ala Gln Pro Lys Glu Asp Glu Glu Glu Asp Asp 
                165                 170                 175     


Asp Val Val Ala Pro Lys Pro Pro Ile Glu Pro Glu Glu Glu Lys Thr 
            180                 185                 190         


Leu Lys Lys Asp Glu Glu Asn Asp Ser Lys Ala Pro Pro His Glu Leu 
        195                 200                 205             


Thr Glu Glu Glu Lys Gln Gln Ile Leu His Ser Glu Glu Phe Leu Ser 
    210                 215                 220                 


Phe Phe Asp His Ser Thr Arg Ile Val Glu Arg Ala Leu Ser Glu Gln 
225                 230                 235                 240 


Ile Asn Ile Phe Phe Asp Tyr Ser Gly Arg Asp Leu Glu Asp Lys Glu 
                245                 250                 255     


Gly Glu Ile Gln Ala Gly Ala Lys Leu Ser Leu Asn Arg Gln Phe Phe 
            260                 265                 270         


Asp Glu Arg Trp Ser Lys His Arg Val Val Ser Cys Leu Asp Trp Ser 
        275                 280                 285             


Ser Gln Tyr Pro Glu Leu Leu Val Ala Ser Tyr Asn Asn Asn Glu Asp 
    290                 295                 300                 


Ala Pro His Glu Pro Asp Gly Val Ala Leu Val Trp Asn Met Lys Tyr 
305                 310                 315                 320 


Lys Lys Thr Thr Pro Glu Tyr Val Phe His Cys Gln Ser Ala Val Met 
                325                 330                 335     


Ser Ala Thr Phe Ala Lys Phe His Pro Asn Leu Val Val Gly Gly Thr 
            340                 345                 350         


Tyr Ser Gly Gln Ile Val Leu Trp Asp Asn Arg Ser Asn Lys Arg Thr 
        355                 360                 365             


Pro Val Gln Arg Thr Pro Leu Ser Ala Ala Ala His Thr His Pro Val 
    370                 375                 380                 


Tyr Cys Val Asn Val Val Gly Thr Gln Asn Ala His Asn Leu Ile Ser 
385                 390                 395                 400 


Ile Ser Thr Asp Gly Lys Ile Cys Ser Trp Ser Leu Asp Met Leu Ser 
                405                 410                 415     


His Pro Gln Asp Ser Met Glu Leu Val His Lys Gln Ser Lys Ala Val 
            420                 425                 430         


Ala Val Thr Ser Met Ser Phe Pro Val Gly Asp Val Asn Asn Phe Val 
        435                 440                 445             


Val Gly Ser Glu Glu Gly Ser Val Tyr Thr Ala Cys Arg His Gly Ser 
    450                 455                 460                 


Lys Ala Gly Ile Ser Glu Met Phe Glu Gly His Gln Gly Pro Ile Thr 
465                 470                 475                 480 


Gly Ile His Cys His Ala Ala Val Gly Ala Val Asp Phe Ser His Leu 
                485                 490                 495     


Phe Val Thr Ser Ser Phe Asp Trp Thr Val Lys Leu Trp Thr Thr Lys 
            500                 505                 510         


Asn Asn Lys Pro Leu Tyr Ser Phe Glu Asp Asn Ala Asp Tyr Val Tyr 
        515                 520                 525             


Asp Val Met Trp Ser Pro Thr His Pro Ala Leu Phe Ala Cys Val Asp 
    530                 535                 540                 


Gly Met Gly Arg Leu Asp Leu Trp Asn Leu Asn Asn Asp Thr Glu Val 
545                 550                 555                 560 


Pro Thr Ala Ser Ile Ser Val Glu Gly Asn Pro Ala Leu Asn Arg Val 
                565                 570                 575     


Arg Trp Thr His Ser Gly Arg Glu Ile Ala Val Gly Asp Ser Glu Gly 
            580                 585                 590         


Gln Ile Val Ile Tyr Asp Val Gly Glu Gln Ile Ala Val Pro Arg Asn 
        595                 600                 605             


Asp Glu Trp Ala Arg Phe Gly Arg Thr Leu Ala Glu Ile Asn Ala Asn 
    610                 615                 620                 


Arg Ala Asp Ala Glu Glu Glu Ala Ala Thr Arg Ile Pro Ala 
625                 630                 635             


<210>  4290
<211>  882
<212>  PRT
<213>  homo sapiens

<400>  4290

Met Ser Leu Phe Lys Ala Arg Asp Trp Trp Ser Thr Ile Leu Gly Asp 
1               5                   10                  15      


Lys Glu Glu Phe Asp Gln Gly Cys Leu Cys Leu Ala Asn Val Asp Asn 
            20                  25                  30          


Ser Gly Asn Gly Gln Asp Lys Ile Ile Val Gly Ser Phe Met Gly Tyr 
        35                  40                  45              


Leu Arg Ile Phe Ser Pro His Pro Ala Lys Thr Gly Asp Gly Ala Gln 
    50                  55                  60                  


Ala Glu Asp Leu Leu Leu Glu Val Asp Leu Arg Asp Pro Val Leu Gln 
65                  70                  75                  80  


Val Glu Val Gly Lys Phe Val Ser Gly Thr Glu Met Leu His Leu Ala 
                85                  90                  95      


Val Leu His Ser Arg Lys Leu Cys Val Tyr Ser Val Ser Gly Thr Leu 
            100                 105                 110         


Gly Asn Val Glu His Gly Asn Gln Cys Gln Met Lys Leu Met Tyr Glu 
        115                 120                 125             


His Asn Leu Gln Arg Thr Ala Cys Asn Met Thr Tyr Gly Ser Phe Gly 
    130                 135                 140                 


Gly Val Lys Gly Arg Asp Leu Ile Cys Ile Gln Ser Met Asp Gly Met 
145                 150                 155                 160 


Leu Met Val Phe Glu Gln Glu Ser Tyr Ala Phe Gly Arg Phe Leu Pro 
                165                 170                 175     


Gly Phe Leu Leu Pro Gly Pro Leu Ala Tyr Ser Ser Arg Thr Asp Ser 
            180                 185                 190         


Phe Leu Thr Val Ser Ser Cys Gln Gln Val Glu Ser Tyr Lys Tyr Gln 
        195                 200                 205             


Val Leu Ala Phe Ala Thr Asp Ala Asp Lys Arg Gln Glu Thr Glu Gln 
    210                 215                 220                 


Gln Lys Leu Gly Ser Gly Lys Arg Leu Val Val Asp Trp Thr Leu Asn 
225                 230                 235                 240 


Ile Gly Glu Gln Ala Leu Asp Ile Cys Ile Val Ser Phe Asn Gln Ser 
                245                 250                 255     


Ala Ser Ser Val Phe Val Leu Gly Glu Arg Asn Phe Phe Cys Leu Lys 
            260                 265                 270         


Asp Asn Gly Gln Ile Arg Phe Met Lys Lys Leu Asp Trp Ser Pro Ser 
        275                 280                 285             


Cys Phe Leu Pro Tyr Cys Ser Val Ser Glu Gly Thr Ile Asn Thr Leu 
    290                 295                 300                 


Ile Gly Asn His Asn Asn Met Leu His Ile Tyr Gln Asp Val Thr Leu 
305                 310                 315                 320 


Lys Trp Ala Thr Gln Leu Pro His Ile Pro Val Ala Val Arg Val Gly 
                325                 330                 335     


Cys Leu His Asp Leu Lys Gly Val Ile Val Thr Leu Ser Asp Asp Gly 
            340                 345                 350         


His Leu Gln Cys Ser Tyr Leu Gly Thr Asp Pro Ser Leu Phe Gln Ala 
        355                 360                 365             


Pro Asn Val Gln Ser Arg Glu Leu Asn Tyr Asp Glu Leu Asp Val Glu 
    370                 375                 380                 


Met Lys Glu Leu Gln Lys Ile Ile Lys Asp Val Asn Lys Ser Gln Gly 
385                 390                 395                 400 


Val Trp Pro Met Thr Glu Arg Glu Asp Asp Leu Asn Val Ser Val Val 
                405                 410                 415     


Val Ser Pro Asn Phe Asp Ser Val Ser Gln Ala Thr Asp Val Glu Val 
            420                 425                 430         


Gly Thr Asp Leu Val Pro Ser Val Thr Val Lys Val Thr Leu Gln Asn 
        435                 440                 445             


Arg Val Ile Leu Gln Lys Ala Lys Leu Ser Val Tyr Val Gln Pro Pro 
    450                 455                 460                 


Leu Glu Leu Thr Cys Asp Gln Phe Thr Phe Glu Phe Met Thr Pro Asp 
465                 470                 475                 480 


Leu Thr Arg Thr Val Ser Phe Ser Val Tyr Leu Lys Arg Ser Tyr Thr 
                485                 490                 495     


Pro Ser Glu Leu Glu Gly Asn Ala Val Val Ser Tyr Ser Arg Pro Thr 
            500                 505                 510         


Gly Ile Pro Arg Val Ile Gln Cys Lys Phe Arg Leu Pro Leu Lys Leu 
        515                 520                 525             


Ile Cys Leu Pro Gly Gln Pro Ser Lys Thr Ala Ser His Lys Ile Thr 
    530                 535                 540                 


Ile Asp Thr Asn Lys Ser Pro Val Ser Leu Leu Ser Leu Phe Pro Gly 
545                 550                 555                 560 


Phe Ala Ser Gln Ser Asp Asp Asp Gln Val Asn Val Met Gly Phe His 
                565                 570                 575     


Phe Leu Gly Gly Ala Arg Ile Thr Val Leu Ala Ser Lys Thr Ser Gln 
            580                 585                 590         


Arg Tyr Arg Ile Gln Ser Glu Gln Phe Glu Asp Leu Trp Leu Ile Thr 
        595                 600                 605             


Asn Glu Leu Ile Leu Arg Leu Gln Glu Tyr Phe Glu Lys Gln Gly Val 
    610                 615                 620                 


Lys Asp Phe Ala Cys Ser Phe Ser Gly Ser Ile Pro Leu Gln Glu Tyr 
625                 630                 635                 640 


Phe Glu Leu Ile Asp His His Phe Glu Leu Arg Ile Asn Gly Glu Lys 
                645                 650                 655     


Leu Glu Glu Leu Leu Ser Glu Arg Ala Val Gln Phe Arg Ala Ile Gln 
            660                 665                 670         


Arg Arg Leu Leu Ala Arg Phe Lys Asp Lys Thr Pro Ala Pro Leu Gln 
        675                 680                 685             


His Leu Asp Thr Leu Leu Asp Gly Thr Tyr Lys Gln Val Ile Ala Leu 
    690                 695                 700                 


Ala Asp Ala Val Glu Glu Asn Gln Gly Asn Leu Phe Gln Ser Phe Thr 
705                 710                 715                 720 


Arg Leu Lys Ser Ala Thr His Leu Val Ile Leu Leu Ile Ala Leu Trp 
                725                 730                 735     


Gln Lys Leu Ser Ala Asp Gln Val Ala Ile Leu Glu Ala Ala Phe Leu 
            740                 745                 750         


Pro Leu Gln Glu Asp Thr Gln Glu Leu Gly Trp Glu Glu Thr Val Asp 
        755                 760                 765             


Ala Ala Ile Ser His Leu Leu Lys Thr Cys Leu Ser Lys Ser Ser Lys 
    770                 775                 780                 


Glu Gln Ala Leu Asn Leu Asn Ser Gln Leu Asn Ile Pro Lys Asp Thr 
785                 790                 795                 800 


Ser Gln Leu Lys Lys His Ile Thr Leu Leu Cys Asp Arg Leu Ser Lys 
                805                 810                 815     


Gly Gly Arg Leu Cys Leu Ser Thr Asp Ala Ala Ala Pro Gln Thr Met 
            820                 825                 830         


Val Met Pro Gly Gly Cys Thr Thr Ile Pro Glu Ser Asp Leu Glu Glu 
        835                 840                 845             


Arg Ser Val Glu Gln Asp Ser Thr Glu Leu Phe Thr Asn His Arg His 
    850                 855                 860                 


Leu Thr Ala Glu Thr Pro Arg Pro Glu Val Ser Pro Leu Gln Gly Val 
865                 870                 875                 880 


Ser Glu 
        


<210>  4291
<211>  671
<212>  PRT
<213>  homo sapiens

<400>  4291

Met Ala Gln Leu Phe Leu Pro Leu Leu Ala Ala Leu Val Leu Ala Gln 
1               5                   10                  15      


Ala Pro Ala Ala Leu Ala Asp Val Leu Glu Gly Asp Ser Ser Glu Asp 
            20                  25                  30          


Arg Ala Phe Arg Val Arg Ile Ala Gly Asp Ala Pro Leu Gln Gly Val 
        35                  40                  45              


Leu Gly Gly Ala Leu Thr Ile Pro Cys His Val His Tyr Leu Arg Pro 
    50                  55                  60                  


Pro Pro Ser Arg Arg Ala Val Leu Gly Ser Pro Arg Val Lys Trp Thr 
65                  70                  75                  80  


Phe Leu Ser Arg Gly Arg Glu Ala Glu Val Leu Val Ala Arg Gly Val 
                85                  90                  95      


Arg Val Lys Val Asn Glu Ala Tyr Arg Phe Arg Val Ala Leu Pro Ala 
            100                 105                 110         


Tyr Pro Ala Ser Leu Thr Asp Val Ser Leu Ala Leu Ser Glu Leu Arg 
        115                 120                 125             


Pro Asn Asp Ser Gly Ile Tyr Arg Cys Glu Val Gln His Gly Ile Asp 
    130                 135                 140                 


Asp Ser Ser Asp Ala Val Glu Val Lys Val Lys Gly Val Val Phe Leu 
145                 150                 155                 160 


Tyr Arg Glu Gly Ser Ala Arg Tyr Ala Phe Ser Phe Ser Gly Ala Gln 
                165                 170                 175     


Glu Ala Cys Ala Arg Ile Gly Ala His Ile Ala Thr Pro Glu Gln Leu 
            180                 185                 190         


Tyr Ala Ala Tyr Leu Gly Gly Tyr Glu Gln Cys Asp Ala Gly Trp Leu 
        195                 200                 205             


Ser Asp Gln Thr Val Arg Tyr Pro Ile Gln Thr Pro Arg Glu Ala Cys 
    210                 215                 220                 


Tyr Gly Asp Met Asp Gly Phe Pro Gly Val Arg Asn Tyr Gly Val Val 
225                 230                 235                 240 


Asp Pro Asp Asp Leu Tyr Asp Val Tyr Cys Tyr Ala Glu Asp Leu Asn 
                245                 250                 255     


Gly Glu Leu Phe Leu Gly Asp Pro Pro Glu Lys Leu Thr Leu Glu Glu 
            260                 265                 270         


Ala Arg Ala Tyr Cys Gln Glu Arg Gly Ala Glu Ile Ala Thr Thr Gly 
        275                 280                 285             


Gln Leu Tyr Ala Ala Trp Asp Gly Gly Leu Asp His Cys Ser Pro Gly 
    290                 295                 300                 


Trp Leu Ala Asp Gly Ser Val Arg Tyr Pro Ile Val Thr Pro Ser Gln 
305                 310                 315                 320 


Arg Cys Gly Gly Gly Leu Pro Gly Val Lys Thr Leu Phe Leu Phe Pro 
                325                 330                 335     


Asn Gln Thr Gly Phe Pro Asn Lys His Ser Arg Phe Asn Val Tyr Cys 
            340                 345                 350         


Phe Arg Asp Ser Ala Gln Pro Ser Ala Ile Pro Glu Ala Ser Asn Pro 
        355                 360                 365             


Ala Ser Asn Pro Ala Ser Asp Gly Leu Glu Ala Ile Val Thr Val Thr 
    370                 375                 380                 


Glu Thr Leu Glu Glu Leu Gln Leu Pro Gln Glu Ala Thr Glu Ser Glu 
385                 390                 395                 400 


Ser Arg Gly Ala Ile Tyr Ser Ile Pro Ile Met Glu Asp Gly Gly Gly 
                405                 410                 415     


Gly Ser Ser Thr Pro Glu Asp Pro Ala Glu Ala Pro Arg Thr Leu Leu 
            420                 425                 430         


Glu Phe Glu Thr Gln Ser Met Val Pro Pro Thr Gly Phe Ser Glu Glu 
        435                 440                 445             


Glu Gly Lys Ala Leu Glu Glu Glu Glu Lys Tyr Glu Asp Glu Glu Glu 
    450                 455                 460                 


Lys Glu Glu Glu Glu Glu Glu Glu Glu Val Glu Asp Glu Ala Leu Trp 
465                 470                 475                 480 


Ala Trp Pro Ser Glu Leu Ser Ser Pro Gly Pro Glu Ala Ser Leu Pro 
                485                 490                 495     


Thr Glu Pro Ala Ala Gln Glu Glu Ser Leu Ser Gln Ala Pro Ala Arg 
            500                 505                 510         


Ala Val Leu Gln Pro Gly Ala Ser Pro Leu Pro Asp Gly Glu Ser Glu 
        515                 520                 525             


Ala Ser Arg Pro Pro Arg Val His Gly Pro Pro Thr Glu Thr Leu Pro 
    530                 535                 540                 


Thr Pro Arg Glu Arg Asn Leu Ala Ser Pro Ser Pro Ser Thr Leu Val 
545                 550                 555                 560 


Glu Ala Arg Glu Val Gly Glu Ala Thr Gly Gly Pro Glu Leu Ser Gly 
                565                 570                 575     


Val Pro Arg Gly Glu Ser Glu Glu Thr Gly Ser Ser Glu Gly Ala Pro 
            580                 585                 590         


Ser Leu Leu Pro Ala Thr Arg Ala Pro Glu Gly Thr Arg Glu Leu Glu 
        595                 600                 605             


Ala Pro Ser Glu Asp Asn Ser Gly Arg Thr Ala Pro Ala Gly Thr Ser 
    610                 615                 620                 


Val Gln Ala Gln Pro Val Leu Pro Thr Asp Ser Ala Ser Arg Gly Gly 
625                 630                 635                 640 


Val Ala Val Val Pro Ala Ser Gly Asn Ser Ala Gln Gly Ser Thr Ala 
                645                 650                 655     


Leu Ser Ile Leu Leu Leu Phe Phe Pro Leu Gln Leu Trp Val Thr 
            660                 665                 670     


<210>  4292
<211>  808
<212>  PRT
<213>  homo sapiens

<400>  4292

Met Trp Leu Arg Leu Gly Pro Pro Ser Leu Ser Leu Ser Pro Lys Pro 
1               5                   10                  15      


Thr Val Gly Arg Ser Leu Cys Leu Thr Leu Trp Phe Leu Ser Leu Ala 
            20                  25                  30          


Leu Arg Ala Ser Thr Gln Ala Pro Ala Pro Thr Val Asn Thr His Phe 
        35                  40                  45              


Gly Lys Leu Arg Gly Ala Arg Val Pro Leu Pro Ser Glu Ile Leu Gly 
    50                  55                  60                  


Pro Val Asp Gln Tyr Leu Gly Val Pro Tyr Ala Ala Pro Pro Ile Gly 
65                  70                  75                  80  


Glu Lys Arg Phe Leu Pro Pro Glu Pro Pro Pro Ser Trp Ser Gly Ile 
                85                  90                  95      


Arg Asn Ala Thr His Phe Pro Pro Val Cys Pro Gln Asn Ile His Thr 
            100                 105                 110         


Ala Val Pro Glu Val Met Leu Pro Val Trp Phe Thr Ala Asn Leu Asp 
        115                 120                 125             


Ile Val Ala Thr Tyr Ile Gln Glu Pro Asn Glu Asp Cys Leu Tyr Leu 
    130                 135                 140                 


Asn Val Tyr Val Pro Thr Glu Asp Asp Ile Arg Asp Ser Gly Ala Lys 
145                 150                 155                 160 


Pro Val Met Val Tyr Ile His Gly Gly Ser Tyr Met Glu Gly Thr Gly 
                165                 170                 175     


Asn Met Ile Asp Gly Ser Ile Leu Ala Ser Tyr Gly Asn Val Ile Val 
            180                 185                 190         


Ile Thr Leu Asn Tyr Arg Val Gly Val Leu Gly Phe Leu Ser Thr Gly 
        195                 200                 205             


Asp Gln Ala Ala Lys Gly Asn Tyr Gly Leu Leu Asp Gln Ile Gln Ala 
    210                 215                 220                 


Leu Arg Trp Val Ser Glu Asn Ile Ala Phe Phe Gly Gly Asp Pro Arg 
225                 230                 235                 240 


Arg Ile Thr Val Phe Gly Ser Gly Ile Gly Ala Ser Cys Val Ser Leu 
                245                 250                 255     


Leu Thr Leu Ser His His Ser Glu Gly Leu Phe Gln Arg Ala Ile Ile 
            260                 265                 270         


Gln Ser Gly Ser Ala Leu Ser Ser Trp Ala Val Asn Tyr Gln Pro Val 
        275                 280                 285             


Lys Tyr Thr Ser Leu Leu Ala Asp Lys Val Gly Cys Asn Val Leu Asp 
    290                 295                 300                 


Thr Val Asp Met Val Asp Cys Leu Arg Gln Lys Ser Ala Lys Glu Leu 
305                 310                 315                 320 


Val Glu Gln Asp Ile Gln Pro Ala Arg Tyr His Val Ala Phe Gly Pro 
                325                 330                 335     


Val Ile Asp Gly Asp Val Ile Pro Asp Asp Pro Glu Ile Leu Met Glu 
            340                 345                 350         


Gln Gly Glu Phe Leu Asn Tyr Asp Ile Met Leu Gly Val Asn Gln Gly 
        355                 360                 365             


Glu Gly Leu Lys Phe Val Glu Gly Val Val Asp Pro Glu Asp Gly Val 
    370                 375                 380                 


Ser Gly Thr Asp Phe Asp Tyr Ser Val Ser Asn Phe Val Asp Asn Leu 
385                 390                 395                 400 


Tyr Gly Tyr Pro Glu Gly Lys Asp Thr Leu Arg Glu Thr Ile Lys Phe 
                405                 410                 415     


Met Tyr Thr Asp Trp Ala Asp Arg Asp Asn Pro Glu Thr Arg Arg Lys 
            420                 425                 430         


Thr Leu Val Ala Leu Phe Thr Asp His Gln Trp Val Glu Pro Ser Val 
        435                 440                 445             


Val Thr Ala Asp Leu His Ala Arg Tyr Gly Ser Pro Thr Tyr Phe Tyr 
    450                 455                 460                 


Ala Phe Tyr His His Cys Gln Ser Leu Met Lys Pro Ala Trp Ser Asp 
465                 470                 475                 480 


Ala Ala His Gly Asp Glu Val Pro Tyr Val Phe Gly Val Pro Met Val 
                485                 490                 495     


Gly Pro Thr Asp Leu Phe Pro Cys Asn Phe Ser Lys Asn Asp Val Met 
            500                 505                 510         


Leu Ser Ala Val Val Met Thr Tyr Trp Thr Asn Phe Ala Lys Thr Gly 
        515                 520                 525             


Asp Pro Asn Lys Pro Val Pro Gln Asp Thr Lys Phe Ile His Thr Lys 
    530                 535                 540                 


Ala Asn Arg Phe Glu Glu Val Ala Trp Ser Lys Tyr Asn Pro Arg Asp 
545                 550                 555                 560 


Gln Leu Tyr Leu His Ile Gly Leu Lys Pro Arg Val Arg Asp His Tyr 
                565                 570                 575     


Arg Ala Thr Lys Val Ala Phe Trp Lys His Leu Val Pro His Leu Tyr 
            580                 585                 590         


Asn Leu His Asp Met Phe His Tyr Thr Ser Thr Thr Thr Lys Val Pro 
        595                 600                 605             


Pro Pro Asp Thr Thr His Ser Ser His Ile Thr Arg Arg Pro Asn Gly 
    610                 615                 620                 


Lys Thr Trp Ser Thr Lys Arg Pro Ala Ile Ser Pro Ala Tyr Ser Asn 
625                 630                 635                 640 


Glu Asn Ala Gln Gly Ser Trp Asn Gly Asp Gln Asp Ala Gly Pro Leu 
                645                 650                 655     


Leu Val Glu Asn Pro Arg Asp Tyr Ser Thr Glu Leu Ser Val Thr Ile 
            660                 665                 670         


Ala Val Gly Ala Ser Leu Leu Phe Leu Asn Val Leu Ala Phe Ala Ala 
        675                 680                 685             


Leu Tyr Tyr Arg Lys Asp Lys Arg Arg Gln Glu Pro Leu Arg Gln Pro 
    690                 695                 700                 


Ser Pro Gln Arg Gly Ala Gly Ala Pro Glu Leu Gly Ala Ala Pro Glu 
705                 710                 715                 720 


Glu Glu Leu Ala Ala Leu Gln Leu Gly Pro Thr His His Glu Cys Glu 
                725                 730                 735     


Ala Gly Pro Pro His Asp Thr Leu Arg Leu Thr Ala Leu Pro Asp Tyr 
            740                 745                 750         


Thr Leu Thr Leu Arg Arg Ser Pro Asp Asp Ile Pro Leu Met Thr Pro 
        755                 760                 765             


Asn Thr Ile Thr Met Ile Pro Asn Ser Leu Val Gly Leu Gln Thr Leu 
    770                 775                 780                 


His Pro Tyr Asn Thr Phe Ala Ala Gly Phe Asn Ser Thr Gly Leu Pro 
785                 790                 795                 800 


His Ser His Ser Thr Thr Arg Val 
                805             


<210>  4293
<211>  257
<212>  PRT
<213>  homo sapiens

<400>  4293

Met Val Gln Leu Arg Pro Arg Ala Ser Arg Ala Pro Ala Ser Ala Glu 
1               5                   10                  15      


Ala Met Val Asp Glu Gly Gln Leu Ala Ser Glu Glu Glu Glu Ala Glu 
            20                  25                  30          


His Gly Leu Leu Leu Gly Gln Pro Ser Ser Gly Ala Ala Ala Glu Pro 
        35                  40                  45              


Leu Glu Glu Asp Glu Glu Gly Asp Asp Glu Phe Asp Asp Glu Ala Pro 
    50                  55                  60                  


Glu Glu Leu Thr Phe Ala Ser Ala Gln Ala Glu Ala Arg Glu Glu Glu 
65                  70                  75                  80  


Arg Arg Val Arg Glu Thr Val Arg Arg Asp Lys Thr Leu Leu Lys Glu 
                85                  90                  95      


Lys Arg Lys Arg Arg Glu Glu Leu Phe Ile Glu Gln Lys Lys Arg Lys 
            100                 105                 110         


Leu Leu Pro Asp Thr Ile Leu Glu Lys Leu Thr Thr Ala Ser Gln Thr 
        115                 120                 125             


Asn Ile Lys Lys Ser Pro Gly Lys Val Lys Glu Val Asn Leu Gln Lys 
    130                 135                 140                 


Lys Asn Glu Asp Cys Glu Lys Gly Asn Asp Ser Lys Lys Val Lys Val 
145                 150                 155                 160 


Gln Lys Val Gln Ser Val Ser Gln Asn Lys Ser Tyr Leu Ala Val Arg 
                165                 170                 175     


Leu Lys Asp Gln Asp Leu Arg Asp Ser Arg Gln Gln Ala Ala Gln Ala 
            180                 185                 190         


Phe Ile His Asn Ser Leu Tyr Gly Pro Gly Thr Asn Arg Thr Thr Val 
        195                 200                 205             


Asn Lys Phe Leu Ser Leu Ala Asn Lys Arg Leu Pro Val Lys Arg Ala 
    210                 215                 220                 


Ala Val Gln Phe Leu Asn Asn Ala Trp Gly Ile Gln Lys Lys Gln Asn 
225                 230                 235                 240 


Ala Lys Arg Phe Lys Arg Arg Trp Met Val Arg Lys Met Lys Thr Lys 
                245                 250                 255     


Lys 
    


<210>  4294
<211>  529
<212>  PRT
<213>  homo sapiens

<400>  4294

Met Leu Val Leu Phe Glu Thr Ser Val Gly Tyr Ala Ile Phe Lys Val 
1               5                   10                  15      


Leu Asn Glu Lys Lys Leu Gln Glu Val Asp Ser Leu Trp Lys Glu Phe 
            20                  25                  30          


Glu Thr Pro Glu Lys Ala Asn Lys Ile Val Lys Leu Lys His Phe Glu 
        35                  40                  45              


Lys Phe Gln Asp Thr Ala Glu Ala Leu Ala Ala Phe Thr Ala Leu Met 
    50                  55                  60                  


Glu Gly Lys Ile Asn Lys Gln Leu Lys Lys Val Leu Lys Lys Ile Val 
65                  70                  75                  80  


Lys Glu Ala His Glu Pro Leu Ala Val Ala Asp Ala Lys Leu Gly Gly 
                85                  90                  95      


Val Ile Lys Glu Lys Leu Asn Leu Ser Cys Ile His Ser Pro Val Val 
            100                 105                 110         


Asn Glu Leu Met Arg Gly Ile Arg Ser Gln Met Asp Gly Leu Ile Pro 
        115                 120                 125             


Gly Val Glu Pro Arg Glu Met Ala Ala Met Cys Leu Gly Leu Ala His 
    130                 135                 140                 


Ser Leu Ser Arg Tyr Arg Leu Lys Phe Ser Ala Asp Lys Val Asp Thr 
145                 150                 155                 160 


Met Ile Val Gln Ala Ile Ser Leu Leu Asp Asp Leu Asp Lys Glu Leu 
                165                 170                 175     


Asn Asn Tyr Ile Met Arg Cys Arg Glu Trp Tyr Gly Trp His Phe Pro 
            180                 185                 190         


Glu Leu Gly Lys Ile Ile Ser Asp Asn Leu Thr Tyr Cys Lys Cys Leu 
        195                 200                 205             


Gln Lys Val Gly Asp Arg Lys Asn Tyr Ala Ser Ala Lys Leu Ser Glu 
    210                 215                 220                 


Leu Leu Pro Glu Glu Val Glu Ala Glu Val Lys Ala Ala Ala Glu Ile 
225                 230                 235                 240 


Ser Met Gly Thr Glu Val Ser Glu Glu Asp Ile Cys Asn Ile Leu His 
                245                 250                 255     


Leu Cys Thr Gln Val Ile Glu Ile Ser Glu Tyr Arg Thr Gln Leu Tyr 
            260                 265                 270         


Glu Tyr Leu Gln Asn Arg Met Met Ala Ile Ala Pro Asn Val Thr Val 
        275                 280                 285             


Met Val Gly Glu Leu Val Gly Ala Arg Leu Ile Ala His Ala Gly Ser 
    290                 295                 300                 


Leu Leu Asn Leu Ala Lys His Ala Ala Ser Thr Val Gln Ile Leu Gly 
305                 310                 315                 320 


Ala Glu Lys Ala Leu Phe Arg Ala Leu Lys Ser Arg Arg Asp Thr Pro 
                325                 330                 335     


Lys Tyr Gly Leu Ile Tyr His Ala Ser Leu Val Gly Gln Thr Ser Pro 
            340                 345                 350         


Lys His Lys Gly Lys Ile Ser Arg Met Leu Ala Ala Lys Thr Val Leu 
        355                 360                 365             


Ala Ile Arg Tyr Asp Ala Phe Gly Glu Asp Ser Ser Ser Ala Met Gly 
    370                 375                 380                 


Val Glu Asn Arg Ala Lys Leu Glu Ala Arg Leu Arg Thr Leu Glu Asp 
385                 390                 395                 400 


Arg Gly Ile Arg Lys Ile Ser Gly Thr Gly Lys Ala Leu Ala Lys Thr 
                405                 410                 415     


Glu Lys Tyr Glu His Lys Ser Glu Val Lys Thr Tyr Asp Pro Ser Gly 
            420                 425                 430         


Asp Ser Thr Leu Pro Thr Cys Ser Lys Lys Arg Lys Ile Glu Gln Val 
        435                 440                 445             


Asp Lys Glu Asp Glu Ile Thr Glu Lys Lys Ala Lys Lys Ala Lys Ile 
    450                 455                 460                 


Lys Val Lys Val Glu Glu Glu Glu Glu Glu Lys Val Ala Glu Glu Glu 
465                 470                 475                 480 


Glu Thr Ser Val Lys Lys Lys Lys Lys Arg Gly Lys Lys Lys His Ile 
                485                 490                 495     


Lys Glu Glu Pro Leu Ser Glu Glu Glu Pro Cys Thr Ser Thr Ala Ile 
            500                 505                 510         


Ala Ser Pro Glu Lys Lys Lys Lys Lys Lys Lys Lys Arg Glu Asn Glu 
        515                 520                 525             


Asp 
    


<210>  4295
<211>  153
<212>  PRT
<213>  homo sapiens

<400>  4295

Met Asn Ser Lys Gly Gln Tyr Pro Thr Gln Pro Thr Tyr Pro Val Gln 
1               5                   10                  15      


Pro Pro Gly Asn Pro Val Tyr Pro Gln Thr Leu His Leu Pro Gln Ala 
            20                  25                  30          


Pro Pro Tyr Thr Asp Ala Pro Pro Ala Tyr Ser Glu Leu Tyr Arg Pro 
        35                  40                  45              


Ser Phe Val His Pro Gly Ala Ala Thr Val Pro Thr Met Ser Ala Ala 
    50                  55                  60                  


Phe Pro Gly Ala Ser Leu Tyr Leu Pro Met Ala Gln Ser Val Ala Val 
65                  70                  75                  80  


Gly Pro Leu Gly Ser Thr Ile Pro Met Ala Tyr Tyr Pro Val Gly Pro 
                85                  90                  95      


Ile Tyr Pro Pro Gly Ser Thr Val Leu Val Glu Gly Gly Tyr Asp Ala 
            100                 105                 110         


Gly Ala Arg Phe Gly Ala Gly Ala Thr Ala Gly Asn Ile Pro Val Lys 
        115                 120                 125             


Glu Asp Gln Asp His Asp Arg Glu Gln Gly Glu Glu Asp Asn Gly Asp 
    130                 135                 140                 


Asn Asn Leu Glu Arg Arg Gly Lys Met 
145                 150             


<210>  4296
<211>  734
<212>  PRT
<213>  homo sapiens

<400>  4296

Met Arg Pro Ala Val Leu Gly Ser Pro Asp Arg Ala Pro Pro Glu Asp 
1               5                   10                  15      


Glu Gly Pro Val Met Val Lys Leu Glu Asp Ser Glu Glu Glu Gly Glu 
            20                  25                  30          


Ala Ala Leu Trp Asp Pro Gly Pro Glu Ala Ala Arg Leu Arg Phe Arg 
        35                  40                  45              


Cys Phe Arg Tyr Glu Glu Ala Thr Gly Pro Gln Glu Ala Leu Ala Gln 
    50                  55                  60                  


Leu Arg Glu Leu Cys Arg Gln Trp Leu Arg Pro Glu Val Arg Ser Lys 
65                  70                  75                  80  


Glu Gln Met Leu Glu Leu Leu Val Leu Glu Gln Phe Leu Gly Ala Leu 
                85                  90                  95      


Pro Pro Glu Ile Gln Ala Arg Val Gln Gly Gln Arg Pro Gly Ser Pro 
            100                 105                 110         


Glu Glu Ala Ala Ala Leu Val Asp Gly Leu Arg Arg Glu Pro Gly Gly 
        115                 120                 125             


Pro Arg Arg Trp Val Thr Val Gln Val Gln Gly Gln Glu Val Leu Ser 
    130                 135                 140                 


Glu Lys Met Glu Pro Ser Ser Phe Gln Pro Leu Pro Glu Thr Glu Pro 
145                 150                 155                 160 


Pro Thr Pro Glu Pro Gly Pro Lys Thr Pro Pro Arg Thr Met Gln Glu 
                165                 170                 175     


Ser Pro Leu Gly Leu Gln Val Lys Glu Glu Ser Glu Val Thr Glu Asp 
            180                 185                 190         


Ser Asp Phe Leu Glu Ser Gly Pro Leu Ala Ala Thr Gln Glu Ser Val 
        195                 200                 205             


Pro Thr Leu Leu Pro Glu Glu Ala Gln Arg Cys Gly Thr Val Leu Asp 
    210                 215                 220                 


Gln Ile Phe Pro His Ser Lys Thr Gly Pro Glu Gly Pro Ser Trp Arg 
225                 230                 235                 240 


Glu His Pro Arg Ala Leu Trp His Glu Glu Ala Gly Gly Ile Phe Ser 
                245                 250                 255     


Pro Gly Phe Ala Leu Gln Leu Gly Ser Ile Ser Ala Gly Pro Gly Ser 
            260                 265                 270         


Val Ser Pro His Leu His Val Pro Trp Asp Leu Gly Met Ala Gly Leu 
        275                 280                 285             


Ser Gly Gln Ile Gln Ser Pro Ser Arg Glu Gly Gly Phe Ala His Ala 
    290                 295                 300                 


Leu Leu Leu Pro Ser Asp Leu Arg Ser Glu Gln Asp Pro Thr Asp Glu 
305                 310                 315                 320 


Asp Pro Cys Arg Gly Val Gly Pro Ala Leu Ile Thr Thr Arg Trp Arg 
                325                 330                 335     


Ser Pro Arg Gly Arg Ser Arg Gly Arg Pro Ser Thr Gly Gly Gly Val 
            340                 345                 350         


Val Arg Gly Gly Arg Cys Asp Val Cys Gly Lys Val Phe Ser Gln Arg 
        355                 360                 365             


Ser Asn Leu Leu Arg His Gln Lys Ile His Thr Gly Glu Arg Pro Phe 
    370                 375                 380                 


Val Cys Ser Glu Cys Gly Arg Ser Phe Ser Arg Ser Ser His Leu Leu 
385                 390                 395                 400 


Arg His Gln Leu Thr His Thr Glu Glu Arg Pro Phe Val Cys Gly Asp 
                405                 410                 415     


Cys Gly Gln Gly Phe Val Arg Ser Ala Arg Leu Glu Glu His Arg Arg 
            420                 425                 430         


Val His Thr Gly Glu Gln Pro Phe Arg Cys Ala Glu Cys Gly Gln Ser 
        435                 440                 445             


Phe Arg Gln Arg Ser Asn Leu Leu Gln His Gln Arg Ile His Gly Asp 
    450                 455                 460                 


Pro Pro Gly Pro Gly Ala Lys Pro Pro Ala Pro Pro Gly Ala Pro Glu 
465                 470                 475                 480 


Pro Pro Gly Pro Phe Pro Cys Ser Glu Cys Arg Glu Ser Phe Ala Arg 
                485                 490                 495     


Arg Ala Val Leu Leu Glu His Gln Ala Val His Thr Gly Asp Lys Ser 
            500                 505                 510         


Phe Gly Cys Val Glu Cys Gly Glu Arg Phe Gly Arg Arg Ser Val Leu 
        515                 520                 525             


Leu Gln His Arg Arg Val His Ser Gly Glu Arg Pro Phe Ala Cys Ala 
    530                 535                 540                 


Glu Cys Gly Gln Ser Phe Arg Gln Arg Ser Asn Leu Thr Gln His Arg 
545                 550                 555                 560 


Arg Ile His Thr Gly Glu Arg Pro Phe Ala Cys Ala Glu Cys Gly Lys 
                565                 570                 575     


Ala Phe Arg Gln Arg Pro Thr Leu Thr Gln His Leu Arg Val His Thr 
            580                 585                 590         


Gly Glu Lys Pro Phe Ala Cys Pro Glu Cys Gly Gln Arg Phe Ser Gln 
        595                 600                 605             


Arg Leu Lys Leu Thr Arg His Gln Arg Thr His Thr Gly Glu Lys Pro 
    610                 615                 620                 


Tyr His Cys Gly Glu Cys Gly Leu Gly Phe Thr Gln Val Ser Arg Leu 
625                 630                 635                 640 


Thr Glu His Gln Arg Ile His Thr Gly Glu Arg Pro Phe Ala Cys Pro 
                645                 650                 655     


Glu Cys Gly Gln Ser Phe Arg Gln His Ala Asn Leu Thr Gln His Arg 
            660                 665                 670         


Arg Ile His Thr Gly Glu Arg Pro Tyr Ala Cys Pro Glu Cys Gly Lys 
        675                 680                 685             


Ala Phe Arg Gln Arg Pro Thr Leu Thr Gln His Leu Arg Thr His Arg 
    690                 695                 700                 


Arg Glu Lys Pro Phe Ala Cys Gln Asp Cys Gly Arg Arg Phe His Gln 
705                 710                 715                 720 


Ser Thr Lys Leu Ile Gln His Gln Arg Val His Ser Ala Glu 
                725                 730                 


<210>  4297
<211>  734
<212>  PRT
<213>  homo sapiens

<400>  4297

Met Arg Pro Ala Val Leu Gly Ser Pro Asp Arg Ala Pro Pro Glu Asp 
1               5                   10                  15      


Glu Gly Pro Val Met Val Lys Leu Glu Asp Ser Glu Glu Glu Gly Glu 
            20                  25                  30          


Ala Ala Leu Trp Asp Pro Gly Pro Glu Ala Ala Arg Leu Arg Phe Arg 
        35                  40                  45              


Cys Phe Arg Tyr Glu Glu Ala Thr Gly Pro Gln Glu Ala Leu Ala Gln 
    50                  55                  60                  


Leu Arg Glu Leu Cys Arg Gln Trp Leu Arg Pro Glu Val Arg Ser Lys 
65                  70                  75                  80  


Glu Gln Met Leu Glu Leu Leu Val Leu Glu Gln Phe Leu Gly Ala Leu 
                85                  90                  95      


Pro Pro Glu Ile Gln Ala Arg Val Gln Gly Gln Arg Pro Gly Ser Pro 
            100                 105                 110         


Glu Glu Ala Ala Ala Leu Val Asp Gly Leu Arg Arg Glu Pro Gly Gly 
        115                 120                 125             


Pro Arg Arg Trp Val Thr Val Gln Val Gln Gly Gln Glu Val Leu Ser 
    130                 135                 140                 


Glu Lys Met Glu Pro Ser Ser Phe Gln Pro Leu Pro Glu Thr Glu Pro 
145                 150                 155                 160 


Pro Thr Pro Glu Pro Gly Pro Lys Thr Pro Pro Arg Thr Met Gln Glu 
                165                 170                 175     


Ser Pro Leu Gly Leu Gln Val Lys Glu Glu Ser Glu Val Thr Glu Asp 
            180                 185                 190         


Ser Asp Phe Leu Glu Ser Gly Pro Leu Ala Ala Thr Gln Glu Ser Val 
        195                 200                 205             


Pro Thr Leu Leu Pro Glu Glu Ala Gln Arg Cys Gly Thr Val Leu Asp 
    210                 215                 220                 


Gln Ile Phe Pro His Ser Lys Thr Gly Pro Glu Gly Pro Ser Trp Arg 
225                 230                 235                 240 


Glu His Pro Arg Ala Leu Trp His Glu Glu Ala Gly Gly Ile Phe Ser 
                245                 250                 255     


Pro Gly Phe Ala Leu Gln Leu Gly Ser Ile Ser Ala Gly Pro Gly Ser 
            260                 265                 270         


Val Ser Pro His Leu His Val Pro Trp Asp Leu Gly Met Ala Gly Leu 
        275                 280                 285             


Ser Gly Gln Ile Gln Ser Pro Ser Arg Glu Gly Gly Phe Ala His Ala 
    290                 295                 300                 


Leu Leu Leu Pro Ser Asp Leu Arg Ser Glu Gln Asp Pro Thr Asp Glu 
305                 310                 315                 320 


Asp Pro Cys Arg Gly Val Gly Pro Ala Leu Ile Thr Thr Arg Trp Arg 
                325                 330                 335     


Ser Pro Arg Gly Arg Ser Arg Gly Arg Pro Ser Thr Gly Gly Gly Val 
            340                 345                 350         


Val Arg Gly Gly Arg Cys Asp Val Cys Gly Lys Val Phe Ser Gln Arg 
        355                 360                 365             


Ser Asn Leu Leu Arg His Gln Lys Ile His Thr Gly Glu Arg Pro Phe 
    370                 375                 380                 


Val Cys Ser Glu Cys Gly Arg Ser Phe Ser Arg Ser Ser His Leu Leu 
385                 390                 395                 400 


Arg His Gln Leu Thr His Thr Glu Glu Arg Pro Phe Val Cys Gly Asp 
                405                 410                 415     


Cys Gly Gln Gly Phe Val Arg Ser Ala Arg Leu Glu Glu His Arg Arg 
            420                 425                 430         


Val His Thr Gly Glu Gln Pro Phe Arg Cys Ala Glu Cys Gly Gln Ser 
        435                 440                 445             


Phe Arg Gln Arg Ser Asn Leu Leu Gln His Gln Arg Ile His Gly Asp 
    450                 455                 460                 


Pro Pro Gly Pro Gly Ala Lys Pro Pro Ala Pro Pro Gly Ala Pro Glu 
465                 470                 475                 480 


Pro Pro Gly Pro Phe Pro Cys Ser Glu Cys Arg Glu Ser Phe Ala Arg 
                485                 490                 495     


Arg Ala Val Leu Leu Glu His Gln Ala Val His Thr Gly Asp Lys Ser 
            500                 505                 510         


Phe Gly Cys Val Glu Cys Gly Glu Arg Phe Gly Arg Arg Ser Val Leu 
        515                 520                 525             


Leu Gln His Arg Arg Val His Ser Gly Glu Arg Pro Phe Ala Cys Ala 
    530                 535                 540                 


Glu Cys Gly Gln Ser Phe Arg Gln Arg Ser Asn Leu Thr Gln His Arg 
545                 550                 555                 560 


Arg Ile His Thr Gly Glu Arg Pro Phe Ala Cys Ala Glu Cys Gly Lys 
                565                 570                 575     


Ala Phe Arg Gln Arg Pro Thr Leu Thr Gln His Leu Arg Val His Thr 
            580                 585                 590         


Gly Glu Lys Pro Phe Ala Cys Pro Glu Cys Gly Gln Arg Phe Ser Gln 
        595                 600                 605             


Arg Leu Lys Leu Thr Arg His Gln Arg Thr His Thr Gly Glu Lys Pro 
    610                 615                 620                 


Tyr His Cys Gly Glu Cys Gly Leu Gly Phe Thr Gln Val Ser Arg Leu 
625                 630                 635                 640 


Thr Glu His Gln Arg Ile His Thr Gly Glu Arg Pro Phe Ala Cys Pro 
                645                 650                 655     


Glu Cys Gly Gln Ser Phe Arg Gln His Ala Asn Leu Thr Gln His Arg 
            660                 665                 670         


Arg Ile His Thr Gly Glu Arg Pro Tyr Ala Cys Pro Glu Cys Gly Lys 
        675                 680                 685             


Ala Phe Arg Gln Arg Pro Thr Leu Thr Gln His Leu Arg Thr His Arg 
    690                 695                 700                 


Arg Glu Lys Pro Phe Ala Cys Gln Asp Cys Gly Arg Arg Phe His Gln 
705                 710                 715                 720 


Ser Thr Lys Leu Ile Gln His Gln Arg Val His Ser Ala Glu 
                725                 730                 


<210>  4298
<211>  169
<212>  PRT
<213>  homo sapiens

<400>  4298

Met Lys Gly Ser Arg Ile Glu Leu Gly Asp Val Thr Pro His Asn Ile 
1               5                   10                  15      


Lys Gln Leu Lys Arg Leu Asn Gln Val Ile Phe Pro Val Ser Tyr Asn 
            20                  25                  30          


Asp Lys Phe Tyr Lys Asp Val Leu Glu Val Gly Glu Leu Ala Lys Leu 
        35                  40                  45              


Ala Tyr Phe Asn Asp Ile Ala Val Gly Ala Val Cys Cys Arg Val Asp 
    50                  55                  60                  


His Ser Gln Asn Gln Lys Arg Leu Tyr Ile Met Thr Leu Gly Cys Leu 
65                  70                  75                  80  


Ala Pro Tyr Arg Arg Leu Gly Ile Gly Thr Lys Met Leu Asn His Val 
                85                  90                  95      


Leu Asn Ile Cys Glu Lys Asp Gly Thr Phe Asp Asn Ile Tyr Leu His 
            100                 105                 110         


Val Gln Ile Ser Asn Glu Ser Ala Ile Asp Phe Tyr Arg Lys Phe Gly 
        115                 120                 125             


Phe Glu Ile Ile Glu Thr Lys Lys Asn Tyr Tyr Lys Arg Ile Glu Pro 
    130                 135                 140                 


Ala Asp Ala His Val Leu Gln Lys Asn Leu Lys Val Pro Ser Gly Gln 
145                 150                 155                 160 


Asn Ala Asp Val Gln Lys Thr Asp Asn 
                165                 


<210>  4299
<211>  730
<212>  PRT
<213>  homo sapiens

<400>  4299

Met Leu Phe Asn Ser Val Leu Arg Gln Pro Gln Leu Gly Val Leu Arg 
1               5                   10                  15      


Asn Gly Trp Ser Ser Gln Tyr Pro Leu Gln Ser Leu Leu Thr Gly Tyr 
            20                  25                  30          


Gln Cys Ser Gly Asn Asp Glu His Thr Ser Tyr Gly Glu Thr Gly Val 
        35                  40                  45              


Pro Val Pro Pro Phe Gly Cys Thr Phe Ser Ser Ala Pro Asn Met Glu 
    50                  55                  60                  


His Val Leu Ala Val Ala Asn Glu Glu Gly Phe Val Arg Leu Tyr Asn 
65                  70                  75                  80  


Thr Glu Ser Gln Ser Phe Arg Lys Lys Cys Phe Lys Glu Trp Met Ala 
                85                  90                  95      


His Trp Asn Ala Val Phe Asp Leu Ala Trp Val Pro Gly Glu Leu Lys 
            100                 105                 110         


Leu Val Thr Ala Ala Gly Asp Gln Thr Ala Lys Phe Trp Asp Val Lys 
        115                 120                 125             


Ala Gly Glu Leu Ile Gly Thr Cys Lys Gly His Gln Cys Ser Leu Lys 
    130                 135                 140                 


Ser Val Ala Phe Ser Lys Phe Glu Lys Ala Val Phe Cys Thr Gly Gly 
145                 150                 155                 160 


Arg Asp Gly Asn Ile Met Val Trp Asp Thr Arg Cys Asn Lys Lys Asp 
                165                 170                 175     


Gly Phe Tyr Arg Gln Val Asn Gln Ile Ser Gly Ala His Asn Thr Ser 
            180                 185                 190         


Asp Lys Gln Thr Pro Ser Lys Pro Lys Lys Lys Gln Asn Ser Lys Gly 
        195                 200                 205             


Leu Ala Pro Ser Val Asp Phe Gln Gln Ser Val Thr Val Val Leu Phe 
    210                 215                 220                 


Gln Asp Glu Asn Thr Leu Val Ser Ala Gly Ala Val Asp Gly Ile Ile 
225                 230                 235                 240 


Lys Val Trp Asp Leu Arg Lys Asn Tyr Thr Ala Tyr Arg Gln Glu Pro 
                245                 250                 255     


Ile Ala Ser Lys Ser Phe Leu Tyr Pro Gly Ser Ser Thr Arg Lys Leu 
            260                 265                 270         


Gly Tyr Ser Ser Leu Ile Leu Asp Ser Thr Gly Ser Thr Leu Phe Ala 
        275                 280                 285             


Asn Cys Thr Asp Asp Asn Ile Tyr Met Phe Asn Met Thr Gly Leu Lys 
    290                 295                 300                 


Thr Ser Pro Val Ala Ile Phe Asn Gly His Gln Asn Ser Thr Phe Tyr 
305                 310                 315                 320 


Val Lys Ser Ser Leu Ser Pro Asp Asp Gln Phe Leu Val Ser Gly Ser 
                325                 330                 335     


Ser Asp Glu Ala Ala Tyr Ile Trp Lys Val Ser Thr Pro Trp Gln Pro 
            340                 345                 350         


Pro Thr Val Leu Leu Gly His Ser Gln Glu Val Thr Ser Val Cys Trp 
        355                 360                 365             


Cys Pro Ser Asp Phe Thr Lys Ile Ala Thr Cys Ser Asp Asp Asn Thr 
    370                 375                 380                 


Leu Lys Ile Trp Arg Leu Asn Arg Gly Leu Glu Glu Lys Pro Gly Gly 
385                 390                 395                 400 


Asp Lys Leu Ser Thr Val Gly Trp Ala Ser Gln Lys Lys Lys Glu Ser 
                405                 410                 415     


Arg Pro Gly Leu Val Thr Val Thr Ser Ser Gln Ser Thr Pro Ala Lys 
            420                 425                 430         


Ala Pro Arg Val Lys Cys Asn Pro Ser Asn Ser Ser Pro Ser Ser Ala 
        435                 440                 445             


Ala Cys Ala Pro Ser Cys Ala Gly Asp Leu Pro Leu Pro Ser Asn Thr 
    450                 455                 460                 


Pro Thr Phe Ser Ile Lys Thr Ser Pro Ala Lys Ala Arg Ser Pro Ile 
465                 470                 475                 480 


Asn Arg Arg Gly Ser Val Ser Ser Val Ser Pro Lys Pro Pro Ser Ser 
                485                 490                 495     


Phe Lys Met Ser Ile Arg Asn Trp Val Thr Arg Thr Pro Ser Ser Ser 
            500                 505                 510         


Pro Pro Ile Thr Pro Pro Ala Ser Glu Thr Lys Ile Met Ser Pro Arg 
        515                 520                 525             


Lys Ala Leu Ile Pro Val Ser Gln Lys Ser Ser Gln Ala Glu Ala Cys 
    530                 535                 540                 


Ser Glu Ser Arg Asn Arg Val Lys Arg Arg Leu Asp Ser Ser Cys Leu 
545                 550                 555                 560 


Glu Ser Val Lys Gln Lys Cys Val Lys Ser Cys Asn Cys Val Thr Glu 
                565                 570                 575     


Leu Asp Gly Gln Val Glu Asn Leu His Leu Asp Leu Cys Cys Leu Ala 
            580                 585                 590         


Gly Asn Gln Glu Asp Leu Ser Lys Asp Ser Leu Gly Pro Thr Lys Ser 
        595                 600                 605             


Ser Lys Ile Glu Gly Ala Gly Thr Ser Ile Ser Glu Pro Pro Ser Pro 
    610                 615                 620                 


Ile Ser Pro Tyr Ala Ser Glu Ser Cys Gly Thr Leu Pro Leu Pro Leu 
625                 630                 635                 640 


Arg Pro Cys Gly Glu Gly Ser Glu Met Val Gly Lys Glu Asn Ser Ser 
                645                 650                 655     


Pro Glu Asn Lys Asn Trp Leu Leu Ala Met Ala Ala Lys Arg Lys Ala 
            660                 665                 670         


Glu Asn Pro Ser Pro Arg Ser Pro Ser Ser Gln Thr Pro Asn Ser Arg 
        675                 680                 685             


Arg Gln Ser Gly Lys Thr Leu Pro Ser Pro Val Thr Ile Thr Pro Ser 
    690                 695                 700                 


Ser Met Arg Lys Ile Cys Thr Tyr Phe His Arg Lys Ser Gln Glu Asp 
705                 710                 715                 720 


Phe Cys Gly Pro Glu His Ser Thr Glu Leu 
                725                 730 


<210>  4300
<211>  103
<212>  PRT
<213>  homo sapiens

<400>  4300

Met Ser Gly Arg Gly Lys Gly Gly Lys Gly Leu Gly Lys Gly Gly Ala 
1               5                   10                  15      


Lys Arg His Arg Lys Val Leu Arg Asp Asn Ile Gln Gly Ile Thr Lys 
            20                  25                  30          


Pro Ala Ile Arg Arg Leu Ala Arg Arg Gly Gly Val Lys Arg Ile Ser 
        35                  40                  45              


Gly Leu Ile Tyr Glu Glu Thr Arg Gly Val Leu Lys Val Phe Leu Glu 
    50                  55                  60                  


Asn Val Ile Arg Asp Ala Val Thr Tyr Thr Glu His Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Val Thr Ala Met Asp Val Val Tyr Ala Leu Lys Arg Gln Gly Arg 
                85                  90                  95      


Thr Leu Tyr Gly Phe Gly Gly 
            100             


<210>  4301
<211>  371
<212>  PRT
<213>  homo sapiens

<400>  4301

Met Pro Gln Leu Ser Gly Gly Gly Gly Gly Gly Gly Gly Asp Pro Glu 
1               5                   10                  15      


Leu Cys Ala Thr Asp Glu Met Ile Pro Phe Lys Asp Glu Gly Asp Pro 
            20                  25                  30          


Gln Lys Glu Lys Ile Phe Ala Glu Ile Ser His Pro Glu Glu Glu Gly 
        35                  40                  45              


Asp Leu Ala Asp Ile Lys Ser Ser Leu Val Asn Glu Ser Glu Ile Ile 
    50                  55                  60                  


Pro Ala Ser Asn Gly His Glu Val Ala Arg Gln Ala Gln Thr Ser Gln 
65                  70                  75                  80  


Glu Pro Tyr His Asp Lys Ala Arg Glu His Pro Asp Asp Gly Lys His 
                85                  90                  95      


Pro Asp Gly Gly Leu Tyr Asn Lys Gly Pro Ser Tyr Ser Ser Tyr Ser 
            100                 105                 110         


Gly Tyr Ile Met Met Pro Asn Met Asn Asn Asp Pro Tyr Met Ser Asn 
        115                 120                 125             


Gly Ser Leu Ser Pro Pro Ile Pro Arg Thr Ser Asn Lys Val Pro Val 
    130                 135                 140                 


Val Gln Pro Ser His Ala Val His Pro Leu Thr Pro Leu Ile Thr Tyr 
145                 150                 155                 160 


Ser Asp Glu His Phe Ser Pro Gly Ser His Pro Ser His Ile Pro Ser 
                165                 170                 175     


Asp Val Asn Ser Lys Gln Gly Met Ser Arg His Pro Pro Ala Pro Asp 
            180                 185                 190         


Ile Pro Thr Phe Tyr Pro Leu Ser Pro Gly Gly Val Gly Gln Ile Thr 
        195                 200                 205             


Pro Pro Leu Gly Trp Phe Ser His His Met Ile Pro Gly Pro Pro Gly 
    210                 215                 220                 


Pro His Thr Thr Gly Ile Pro His Pro Ala Ile Val Thr Pro Gln Val 
225                 230                 235                 240 


Lys Gln Glu His Pro His Thr Asp Ser Asp Leu Met His Val Lys Pro 
                245                 250                 255     


Gln His Glu Gln Arg Lys Glu Gln Glu Pro Lys Arg Pro His Ile Lys 
            260                 265                 270         


Lys Pro Leu Asn Ala Phe Met Leu Tyr Met Lys Glu Met Arg Ala Asn 
        275                 280                 285             


Val Val Ala Glu Cys Thr Leu Lys Glu Ser Ala Ala Ile Asn Gln Ile 
    290                 295                 300                 


Leu Gly Arg Arg Trp His Ala Leu Ser Arg Glu Glu Gln Ala Lys Tyr 
305                 310                 315                 320 


Tyr Glu Leu Ala Arg Lys Glu Arg Gln Leu His Met Gln Leu Tyr Pro 
                325                 330                 335     


Gly Trp Ser Ala Arg Asp Asn Tyr Gly Lys Lys Lys Lys Arg Lys Arg 
            340                 345                 350         


Glu Lys Leu Gln Glu Ser Ala Ser Gly Thr Gly Pro Arg Met Thr Ala 
        355                 360                 365             


Ala Tyr Ile 
    370     


<210>  4302
<211>  691
<212>  PRT
<213>  homo sapiens

<400>  4302

Met Ser Ala Leu Leu Gln Asp Pro Met Ile Ala Gly Gln Val Ser Lys 
1               5                   10                  15      


Pro Leu Leu Ser Val Arg Ser Glu Met Asn Ala Glu Leu Arg Gly Glu 
            20                  25                  30          


Asp Lys Ala Ala Thr Ser Asp Ser Glu Leu Asn Glu Pro Leu Leu Ala 
        35                  40                  45              


Pro Val Glu Ser Asn Asp Ser Glu Asp Thr Pro Ser Lys Leu Phe Gly 
    50                  55                  60                  


Ala Arg Gly Asn Pro Ala Leu Ser Asp Pro Gly Thr Pro Asp Gln His 
65                  70                  75                  80  


Gln Ala Ser Gln Thr His Pro Pro Phe Pro Val Gly Pro Gln Pro Leu 
                85                  90                  95      


Leu Thr Ala Gln Gln Leu Ala Ser Ala Val Ala Gly Val Met Pro Gly 
            100                 105                 110         


Gly Pro Pro Ala Leu Asn Gln Pro Ile Leu Ile Pro Phe Asn Met Ala 
        115                 120                 125             


Gly Gln Leu Gly Gly Gln Gln Gly Leu Val Leu Thr Leu Pro Thr Ala 
    130                 135                 140                 


Asn Leu Thr Asn Ile Gln Gly Leu Val Ala Ala Ala Ala Ala Gly Gly 
145                 150                 155                 160 


Ile Met Thr Leu Pro Leu Gln Asn Leu Gln Ala Thr Ser Ser Leu Asn 
                165                 170                 175     


Ser Gln Leu Gln Gln Leu Gln Leu Gln Leu Gln Gln Gln Gln Gln Gln 
            180                 185                 190         


Gln Gln Gln Gln Pro Pro Pro Ser Thr Asn Gln His Pro Gln Pro Ala 
        195                 200                 205             


Pro Gln Ala Pro Ser Gln Ser Gln Gln Gln Pro Leu Gln Pro Thr Pro 
    210                 215                 220                 


Pro Gln Gln Pro Pro Pro Ala Ser Gln Gln Pro Pro Ala Pro Thr Ser 
225                 230                 235                 240 


Gln Leu Gln Gln Ala Pro Gln Pro Gln Gln His Gln Pro His Ser His 
                245                 250                 255     


Ser Gln Asn Gln Asn Gln Pro Ser Pro Thr Gln Gln Ser Ser Ser Pro 
            260                 265                 270         


Pro Gln Lys Pro Ser Gln Ser Pro Gly His Gly Leu Pro Ser Pro Leu 
        275                 280                 285             


Thr Pro Pro Asn Pro Leu Gln Leu Val Asn Asn Pro Leu Ala Ser Gln 
    290                 295                 300                 


Ala Ala Ala Ala Ala Ala Ala Met Ser Ser Ile Ala Ser Ser Gln Ala 
305                 310                 315                 320 


Phe Gly Asn Ala Leu Ser Ser Leu Gln Gly Val Thr Gly Gln Leu Val 
                325                 330                 335     


Thr Asn Ala Gln Gly Gln Ile Ile Gly Thr Ile Pro Leu Met Pro Asn 
            340                 345                 350         


Pro Gly Pro Ser Ser Gln Ala Ala Ser Gly Thr Gln Gly Leu Gln Val 
        355                 360                 365             


Gln Pro Ile Thr Pro Gln Leu Leu Thr Asn Ala Gln Gly Gln Ile Ile 
    370                 375                 380                 


Ala Thr Val Ile Gly Asn Gln Ile Leu Pro Val Ile Asn Thr Gln Gly 
385                 390                 395                 400 


Ile Thr Leu Ser Pro Ile Lys Pro Gly Gln Gln Leu His Gln Pro Ser 
                405                 410                 415     


Gln Thr Ser Val Gly Gln Ala Ala Ser Gln Gly Asn Leu Leu His Leu 
            420                 425                 430         


Ala His Ser Gln Ala Ser Met Ser Gln Ser Pro Val Arg Gln Ala Ser 
        435                 440                 445             


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ala Leu Ser Val Gly Gln 
    450                 455                 460                 


Leu Val Ser Asn Pro Gln Thr Ala Ala Gly Glu Val Asp Gly Val Asn 
465                 470                 475                 480 


Leu Glu Glu Ile Arg Glu Phe Ala Lys Ala Phe Lys Ile Arg Arg Leu 
                485                 490                 495     


Ser Leu Gly Leu Thr Gln Thr Gln Val Gly Gln Ala Leu Ser Ala Thr 
            500                 505                 510         


Glu Gly Pro Ala Tyr Ser Gln Ser Ala Ile Cys Arg His Thr Ile Leu 
        515                 520                 525             


Arg Ser His Phe Phe Leu Pro Gln Glu Ala Gln Glu Asn Thr Ile Ala 
    530                 535                 540                 


Ser Ser Leu Thr Ala Lys Leu Asn Pro Gly Leu Leu Tyr Pro Ala Arg 
545                 550                 555                 560 


Phe Glu Lys Leu Asp Ile Thr Pro Lys Ser Ala Gln Lys Ile Lys Pro 
                565                 570                 575     


Val Leu Glu Arg Trp Met Ala Glu Ala Glu Ala Arg His Arg Ala Gly 
            580                 585                 590         


Met Gln Asn Leu Thr Glu Phe Ile Gly Ser Glu Pro Ser Lys Lys Arg 
        595                 600                 605             


Lys Arg Arg Thr Ser Phe Thr Pro Gln Ala Leu Glu Ile Leu Asn Ala 
    610                 615                 620                 


His Phe Glu Lys Asn Thr His Pro Ser Gly Gln Glu Met Thr Glu Ile 
625                 630                 635                 640 


Ala Glu Lys Leu Asn Tyr Asp Arg Glu Val Val Arg Val Trp Phe Cys 
                645                 650                 655     


Asn Lys Arg Gln Ala Leu Lys Asn Thr Ile Lys Arg Leu Lys Gln His 
            660                 665                 670         


Glu Pro Ala Thr Ala Val Pro Leu Glu Pro Leu Thr Asp Ser Leu Glu 
        675                 680                 685             


Glu Asn Ser 
    690     


<210>  4303
<211>  595
<212>  PRT
<213>  homo sapiens

<400>  4303

Met Ala Ala Val Val Gln Gln Asn Asp Leu Val Phe Glu Phe Ala Ser 
1               5                   10                  15      


Asn Val Met Glu Asp Glu Arg Gln Leu Gly Asp Pro Ala Ile Phe Pro 
            20                  25                  30          


Ala Val Ile Val Glu His Val Pro Gly Ala Asp Ile Leu Asn Ser Tyr 
        35                  40                  45              


Ala Gly Leu Ala Cys Val Glu Glu Pro Asn Asp Met Ile Thr Glu Ser 
    50                  55                  60                  


Ser Leu Asp Val Ala Glu Glu Glu Ile Ile Asp Asp Asp Asp Asp Asp 
65                  70                  75                  80  


Ile Thr Leu Thr Val Glu Ala Ser Cys His Asp Gly Asp Glu Thr Ile 
                85                  90                  95      


Glu Thr Ile Glu Ala Ala Glu Ala Leu Leu Asn Met Asp Ser Pro Gly 
            100                 105                 110         


Pro Met Leu Asp Glu Lys Arg Ile Asn Gly Ile Pro Glu Val Met Glu 
        115                 120                 125             


Thr Gln Gln Val Gln Glu Lys Tyr Ala Asp Ser Pro Gly Ala Ser Ser 
    130                 135                 140                 


Pro Glu Gln Pro Lys Arg Lys Lys Gly Arg Lys Thr Lys Pro Pro Arg 
145                 150                 155                 160 


Pro Asp Ser Pro Ala Thr Thr Pro Asn Ile Ser Val Lys Lys Lys Asn 
                165                 170                 175     


Lys Asp Gly Lys Gly Asn Thr Ile Tyr Leu Trp Glu Phe Leu Leu Ala 
            180                 185                 190         


Leu Leu Gln Asp Lys Ala Thr Cys Pro Lys Tyr Ile Lys Trp Thr Gln 
        195                 200                 205             


Arg Glu Lys Gly Ile Phe Lys Leu Val Asp Ser Lys Ala Val Ser Arg 
    210                 215                 220                 


Leu Trp Gly Lys His Lys Asn Lys Pro Asp Met Asn Tyr Glu Thr Met 
225                 230                 235                 240 


Gly Arg Ala Leu Arg Tyr Tyr Tyr Gln Arg Gly Ile Leu Ala Lys Val 
                245                 250                 255     


Glu Gly Gln Arg Leu Val Tyr Gln Phe Lys Glu Met Pro Lys Asp Leu 
            260                 265                 270         


Ile Tyr Ile Asn Asp Glu Asp Pro Ser Ser Ser Ile Glu Ser Ser Asp 
        275                 280                 285             


Pro Ser Leu Ser Ser Ser Ala Thr Ser Asn Arg Asn Gln Thr Ser Arg 
    290                 295                 300                 


Ser Arg Val Ser Ser Ser Pro Gly Val Lys Gly Gly Ala Thr Thr Val 
305                 310                 315                 320 


Leu Lys Pro Gly Asn Ser Lys Ala Ala Lys Pro Lys Asp Pro Val Glu 
                325                 330                 335     


Val Ala Gln Pro Ser Glu Val Leu Arg Thr Val Gln Pro Thr Gln Ser 
            340                 345                 350         


Pro Tyr Pro Thr Gln Leu Phe Arg Thr Val His Val Val Gln Pro Val 
        355                 360                 365             


Gln Ala Val Pro Glu Gly Glu Ala Ala Arg Thr Ser Thr Met Gln Asp 
    370                 375                 380                 


Glu Thr Leu Asn Ser Ser Val Gln Ser Ile Arg Thr Ile Gln Ala Pro 
385                 390                 395                 400 


Thr Gln Val Pro Val Val Val Ser Pro Arg Asn Gln Gln Leu His Thr 
                405                 410                 415     


Val Thr Leu Gln Thr Val Pro Leu Thr Thr Val Ile Ala Ser Thr Asp 
            420                 425                 430         


Pro Ser Ala Gly Thr Gly Ser Gln Lys Phe Ile Leu Gln Ala Ile Pro 
        435                 440                 445             


Ser Ser Gln Pro Met Thr Val Leu Lys Glu Asn Val Met Leu Gln Ser 
    450                 455                 460                 


Gln Lys Ala Gly Ser Pro Pro Ser Ile Val Leu Gly Pro Ala Gln Val 
465                 470                 475                 480 


Gln Gln Val Leu Thr Ser Asn Val Gln Thr Ile Cys Asn Gly Thr Val 
                485                 490                 495     


Ser Val Ala Ser Ser Pro Ser Phe Ser Ala Thr Ala Pro Val Val Thr 
            500                 505                 510         


Phe Ser Pro Arg Ser Ser Gln Leu Val Ala His Pro Pro Gly Thr Val 
        515                 520                 525             


Ile Thr Ser Val Ile Lys Thr Gln Glu Thr Lys Thr Leu Thr Gln Glu 
    530                 535                 540                 


Val Glu Lys Lys Glu Ser Glu Asp His Leu Lys Glu Asn Thr Glu Lys 
545                 550                 555                 560 


Thr Glu Gln Gln Pro Gln Pro Tyr Val Met Val Val Ser Ser Ser Asn 
                565                 570                 575     


Gly Phe Thr Ser Gln Val Ala Met Lys Gln Asn Glu Leu Leu Glu Pro 
            580                 585                 590         


Asn Ser Phe 
        595 


<210>  4304
<211>  419
<212>  PRT
<213>  homo sapiens

<400>  4304

Met Leu Gln Asp Leu Ser Ala Ser Val Phe Phe Pro Pro Cys Ser Gln 
1               5                   10                  15      


His Arg Thr Leu Val Ala Phe His Gly Leu Pro Leu Lys Ile Lys Lys 
            20                  25                  30          


Glu Pro His Ser Pro Cys Ser Glu Ile Ser Ser Ala Cys Ser Gln Glu 
        35                  40                  45              


Gln Pro Phe Lys Phe Ser Tyr Gly Glu Lys Cys Leu Tyr Asn Val Ser 
    50                  55                  60                  


Ala Tyr Asp Gln Lys Pro Gln Val Gly Met Arg Pro Ser Asn Pro Pro 
65                  70                  75                  80  


Thr Pro Ser Ser Thr Pro Val Ser Pro Leu His His Ala Ser Pro Asn 
                85                  90                  95      


Ser Thr His Thr Pro Lys Pro Asp Arg Ala Phe Pro Ala His Leu Pro 
            100                 105                 110         


Pro Ser Gln Ser Ile Pro Asp Ser Ser Tyr Pro Met Asp His Arg Phe 
        115                 120                 125             


Arg Arg Gln Leu Ser Glu Pro Cys Asn Ser Phe Pro Pro Leu Pro Thr 
    130                 135                 140                 


Met Pro Arg Glu Gly Arg Pro Met Tyr Gln Arg Gln Met Ser Glu Pro 
145                 150                 155                 160 


Asn Ile Pro Phe Pro Pro Gln Gly Phe Lys Gln Glu Tyr His Asp Pro 
                165                 170                 175     


Val Tyr Glu His Asn Thr Met Val Gly Ser Ala Ala Ser Gln Ser Phe 
            180                 185                 190         


Pro Pro Pro Leu Met Ile Lys Gln Glu Pro Arg Asp Phe Ala Tyr Asp 
        195                 200                 205             


Ser Glu Val Pro Ser Cys His Ser Ile Tyr Met Arg Gln Glu Gly Phe 
    210                 215                 220                 


Leu Ala His Pro Ser Arg Thr Glu Gly Cys Met Phe Glu Lys Gly Pro 
225                 230                 235                 240 


Arg Gln Phe Tyr Asp Asp Thr Cys Val Val Pro Glu Lys Phe Asp Gly 
                245                 250                 255     


Asp Ile Lys Gln Glu Pro Gly Met Tyr Arg Glu Gly Pro Thr Tyr Gln 
            260                 265                 270         


Arg Arg Gly Ser Leu Gln Leu Trp Gln Phe Leu Val Ala Leu Leu Asp 
        275                 280                 285             


Asp Pro Ser Asn Ser His Phe Ile Ala Trp Thr Gly Arg Gly Met Glu 
    290                 295                 300                 


Phe Lys Leu Ile Glu Pro Glu Glu Val Ala Arg Arg Trp Gly Ile Gln 
305                 310                 315                 320 


Lys Asn Arg Pro Ala Met Asn Tyr Asp Lys Leu Ser Arg Ser Leu Arg 
                325                 330                 335     


Tyr Tyr Tyr Glu Lys Gly Ile Met Gln Lys Val Ala Gly Glu Arg Tyr 
            340                 345                 350         


Val Tyr Lys Phe Val Cys Asp Pro Glu Ala Leu Phe Ser Met Ala Phe 
        355                 360                 365             


Pro Asp Asn Gln Arg Pro Leu Leu Lys Thr Asp Met Glu Arg His Ile 
    370                 375                 380                 


Asn Glu Glu Asp Thr Val Pro Leu Ser His Phe Asp Glu Ser Met Ala 
385                 390                 395                 400 


Tyr Met Pro Glu Gly Gly Cys Cys Asn Pro His Pro Tyr Asn Glu Gly 
                405                 410                 415     


Tyr Val Tyr 
            


<210>  4305
<211>  1742
<212>  PRT
<213>  homo sapiens

<400>  4305

Met Ala Val Ala Glu Leu Tyr Thr Gln Tyr Asn Arg Val Trp Ile Pro 
1               5                   10                  15      


Asp Pro Glu Glu Val Trp Lys Ser Ala Glu Ile Ala Lys Asp Tyr Arg 
            20                  25                  30          


Val Gly Asp Lys Val Leu Arg Leu Leu Leu Glu Asp Gly Thr Glu Leu 
        35                  40                  45              


Asp Tyr Ser Val Asn Pro Glu Ser Leu Pro Pro Leu Arg Asn Pro Asp 
    50                  55                  60                  


Ile Leu Val Gly Glu Asn Asp Leu Thr Ala Leu Ser Tyr Leu His Glu 
65                  70                  75                  80  


Pro Ala Val Leu His Asn Leu Arg Ile Arg Phe Ala Glu Ser Lys Leu 
                85                  90                  95      


Ile Tyr Thr Tyr Ser Gly Ile Ile Leu Val Ala Met Asn Pro Tyr Lys 
            100                 105                 110         


Gln Leu Pro Ile Tyr Gly Asp Ala Ile Ile His Ala Tyr Ser Gly Gln 
        115                 120                 125             


Asn Met Gly Asp Met Asp Pro His Ile Phe Ala Val Ala Glu Glu Ala 
    130                 135                 140                 


Tyr Lys Gln Met Ala Arg Asn Asn Arg Asn Gln Ser Ile Ile Val Ser 
145                 150                 155                 160 


Gly Glu Ser Gly Ala Gly Lys Thr Val Ser Ala Arg Tyr Ala Met Arg 
                165                 170                 175     


Tyr Phe Ala Thr Val Ser Lys Ser Gly Ser Asn Ala His Val Glu Asp 
            180                 185                 190         


Lys Val Leu Ala Ser Asn Pro Ile Thr Glu Ala Val Gly Asn Ala Lys 
        195                 200                 205             


Thr Thr Arg Asn Asp Asn Ser Ser Arg Phe Gly Lys Tyr Thr Glu Ile 
    210                 215                 220                 


Ser Phe Asp Glu Gln Asn Gln Ile Ile Gly Ala Asn Met Ser Thr Tyr 
225                 230                 235                 240 


Leu Leu Glu Lys Ser Arg Val Val Phe Gln Ser Glu Asn Glu Arg Asn 
                245                 250                 255     


Tyr His Ile Phe Tyr Gln Leu Cys Ala Ser Ala Gln Gln Ser Glu Phe 
            260                 265                 270         


Lys His Leu Lys Leu Gly Ser Ala Glu Glu Phe Asn Tyr Thr Arg Met 
        275                 280                 285             


Gly Gly Asn Thr Val Ile Glu Gly Val Asn Asp Arg Ala Glu Met Val 
    290                 295                 300                 


Glu Thr Gln Lys Thr Phe Thr Leu Leu Gly Phe Lys Glu Asp Phe Gln 
305                 310                 315                 320 


Met Asp Val Phe Lys Ile Leu Ala Ala Ile Leu His Leu Gly Asn Val 
                325                 330                 335     


Gln Ile Thr Ala Val Gly Asn Glu Arg Ser Ser Val Ser Glu Asp Asp 
            340                 345                 350         


Ser His Leu Lys Val Phe Cys Glu Leu Leu Gly Leu Glu Ser Gly Arg 
        355                 360                 365             


Val Ala Gln Trp Leu Cys Asn Arg Lys Ile Val Thr Ser Ser Glu Thr 
    370                 375                 380                 


Val Val Lys Pro Met Thr Arg Pro Gln Ala Val Asn Ala Arg Asp Ala 
385                 390                 395                 400 


Leu Ala Lys Lys Ile Tyr Ala His Leu Phe Asp Phe Ile Val Glu Arg 
                405                 410                 415     


Ile Asn Gln Ala Leu Gln Phe Ser Gly Lys Gln His Thr Phe Ile Gly 
            420                 425                 430         


Val Leu Asp Ile Tyr Gly Phe Glu Thr Phe Asp Val Asn Ser Phe Glu 
        435                 440                 445             


Gln Phe Cys Ile Asn Tyr Ala Asn Glu Lys Leu Gln Gln Gln Phe Asn 
    450                 455                 460                 


Met His Val Phe Lys Leu Glu Gln Glu Glu Tyr Met Lys Glu Asp Ile 
465                 470                 475                 480 


Pro Trp Thr Leu Ile Asp Phe Tyr Asp Asn Gln Pro Val Ile Asp Leu 
                485                 490                 495     


Ile Glu Ala Lys Met Gly Ile Leu Glu Leu Leu Asp Glu Glu Cys Leu 
            500                 505                 510         


Leu Pro His Gly Thr Asp Glu Asn Trp Leu Gln Lys Leu Tyr Asn Asn 
        515                 520                 525             


Phe Val Asn Arg Asn Pro Leu Phe Glu Lys Pro Arg Met Ser Asn Thr 
    530                 535                 540                 


Ser Phe Val Ile Gln His Phe Ala Asp Lys Val Glu Tyr Lys Cys Glu 
545                 550                 555                 560 


Gly Phe Leu Glu Lys Asn Arg Asp Thr Val Tyr Asp Met Leu Val Glu 
                565                 570                 575     


Ile Leu Arg Ala Ser Lys Phe His Leu Cys Ala Asn Phe Phe Gln Glu 
            580                 585                 590         


Asn Pro Thr Pro Pro Ser Pro Phe Gly Ser Met Ile Thr Val Lys Ser 
        595                 600                 605             


Ala Lys Gln Val Ile Lys Pro Asn Ser Lys His Phe Arg Thr Thr Val 
    610                 615                 620                 


Gly Ser Lys Phe Arg Ser Ser Leu Tyr Leu Leu Met Glu Thr Leu Asn 
625                 630                 635                 640 


Ala Thr Thr Pro His Tyr Val Arg Cys Ile Lys Pro Asn Asp Glu Lys 
                645                 650                 655     


Leu Pro Phe Glu Phe Asp Ser Lys Arg Ile Val Gln Gln Leu Arg Ala 
            660                 665                 670         


Cys Gly Val Leu Glu Thr Ile Arg Ile Ser Ala Gln Ser Tyr Pro Ser 
        675                 680                 685             


Arg Trp Thr Tyr Ile Glu Phe Tyr Ser Arg Tyr Gly Ile Leu Met Thr 
    690                 695                 700                 


Lys Gln Glu Leu Ser Phe Ser Asp Lys Lys Glu Val Cys Lys Val Val 
705                 710                 715                 720 


Leu His Arg Leu Ile Gln Asp Ser Asn Gln Tyr Gln Phe Gly Lys Thr 
                725                 730                 735     


Lys Ile Phe Phe Arg Ala Gly Gln Val Ala Tyr Leu Glu Lys Leu Arg 
            740                 745                 750         


Leu Asp Lys Leu Arg Gln Ser Cys Val Met Val Gln Lys His Met Arg 
        755                 760                 765             


Gly Trp Leu Gln Arg Lys Lys Phe Leu Arg Glu Arg Arg Ala Ala Leu 
    770                 775                 780                 


Ile Ile Gln Gln Tyr Phe Arg Gly Gln Gln Thr Val Arg Lys Ala Ile 
785                 790                 795                 800 


Thr Ala Val Ala Leu Lys Glu Ala Trp Ala Ala Ile Ile Ile Gln Lys 
                805                 810                 815     


His Cys Arg Gly Tyr Leu Val Arg Ser Leu Tyr Gln Leu Ile Arg Met 
            820                 825                 830         


Ala Thr Ile Thr Met Gln Ala Tyr Ser Arg Gly Phe Leu Ala Arg Arg 
        835                 840                 845             


Arg Tyr Arg Lys Met Leu Glu Glu His Lys Ala Val Ile Leu Gln Lys 
    850                 855                 860                 


Tyr Ala Arg Ala Trp Leu Ala Arg Arg Arg Phe Gln Ser Ile Arg Arg 
865                 870                 875                 880 


Phe Val Leu Asn Ile Gln Leu Thr Tyr Arg Val Gln Arg Leu Gln Lys 
                885                 890                 895     


Lys Leu Glu Asp Gln Asn Lys Glu Asn His Gly Leu Val Glu Lys Leu 
            900                 905                 910         


Thr Ser Leu Ala Ala Leu Arg Ala Gly Asp Val Glu Lys Ile Gln Lys 
        915                 920                 925             


Leu Glu Ala Glu Leu Glu Lys Ala Ala Thr His Arg Arg Asn Tyr Glu 
    930                 935                 940                 


Glu Lys Gly Lys Arg Tyr Arg Asp Ala Val Glu Glu Lys Leu Ala Lys 
945                 950                 955                 960 


Leu Gln Lys His Asn Ser Glu Leu Glu Thr Gln Lys Glu Gln Ile Gln 
                965                 970                 975     


Leu Lys Leu Gln Glu Lys Thr Glu Glu Leu Lys Glu Lys Met Asp Asn 
            980                 985                 990         


Leu Thr Lys Gln Leu Phe Asp Asp  Val Gln Lys Glu Glu  Arg Gln Arg 
        995                 1000                 1005             


Met Leu  Leu Glu Lys Ser Phe  Glu Leu Lys Thr Gln  Asp Tyr Glu 
    1010                 1015                 1020             


Lys Gln  Ile Gln Ser Leu Lys  Glu Glu Ile Lys Ala  Leu Lys Asp 
    1025                 1030                 1035             


Glu Lys  Met Gln Leu Gln His  Leu Val Glu Gly Glu  His Val Thr 
    1040                 1045                 1050             


Ser Asp  Gly Leu Lys Ala Glu  Val Ala Arg Leu Ser  Lys Gln Val 
    1055                 1060                 1065             


Lys Thr  Ile Ser Glu Phe Glu  Lys Glu Ile Glu Leu  Leu Gln Ala 
    1070                 1075                 1080             


Gln Lys  Ile Asp Val Glu Lys  His Val Gln Ser Gln  Lys Arg Glu 
    1085                 1090                 1095             


Met Arg  Glu Lys Met Ser Glu  Ile Thr Lys Gln Leu  Leu Glu Ser 
    1100                 1105                 1110             


Tyr Asp  Ile Glu Asp Val Arg  Ser Arg Leu Ser Val  Glu Asp Leu 
    1115                 1120                 1125             


Glu His  Leu Asn Glu Asp Gly  Glu Leu Trp Phe Ala  Tyr Glu Gly 
    1130                 1135                 1140             


Leu Lys  Lys Ala Thr Arg Val  Leu Glu Ser His Phe  Gln Ser Gln 
    1145                 1150                 1155             


Lys Asp  Cys Tyr Glu Lys Glu  Ile Glu Ala Leu Asn  Phe Lys Val 
    1160                 1165                 1170             


Val His  Leu Ser Gln Glu Ile  Asn His Leu Gln Lys  Leu Phe Arg 
    1175                 1180                 1185             


Glu Glu  Asn Asp Ile Asn Glu  Ser Ile Arg His Glu  Val Thr Arg 
    1190                 1195                 1200             


Leu Thr  Ser Glu Asn Met Met  Ile Pro Asp Phe Lys  Gln Gln Ile 
    1205                 1210                 1215             


Ser Glu  Leu Glu Lys Gln Lys  Gln Asp Leu Glu Ile  Arg Leu Asn 
    1220                 1225                 1230             


Glu Gln  Ala Glu Lys Met Lys  Gly Lys Leu Glu Glu  Leu Ser Asn 
    1235                 1240                 1245             


Gln Leu  His Arg Ser Gln Glu  Glu Glu Gly Thr Gln  Arg Lys Ala 
    1250                 1255                 1260             


Leu Glu  Ala Gln Asn Glu Ile  His Thr Lys Glu Lys  Glu Lys Leu 
    1265                 1270                 1275             


Ile Asp  Lys Ile Gln Glu Met  Gln Glu Ala Ser Asp  His Leu Lys 
    1280                 1285                 1290             


Lys Gln  Phe Glu Thr Glu Ser  Glu Val Lys Cys Asn  Phe Arg Gln 
    1295                 1300                 1305             


Glu Ala  Ser Arg Leu Thr Leu  Glu Asn Arg Asp Leu  Glu Glu Glu 
    1310                 1315                 1320             


Leu Asp  Met Lys Asp Arg Val  Ile Lys Lys Leu Gln  Asp Gln Val 
    1325                 1330                 1335             


Lys Thr  Leu Ser Lys Thr Ile  Gly Lys Ala Asn Asp  Val His Ser 
    1340                 1345                 1350             


Ser Ser  Gly Pro Lys Glu Tyr  Leu Gly Met Leu Gln  Tyr Lys Arg 
    1355                 1360                 1365             


Glu Asp  Glu Ala Lys Leu Ile  Gln Asn Leu Ile Leu  Asp Leu Lys 
    1370                 1375                 1380             


Pro Arg  Gly Val Val Val Asn  Met Ile Pro Gly Leu  Pro Ala His 
    1385                 1390                 1395             


Ile Leu  Phe Met Cys Val Arg  Tyr Ala Asp Ser Leu  Asn Asp Ala 
    1400                 1405                 1410             


Asn Met  Leu Lys Ser Leu Met  Asn Ser Thr Ile Asn  Gly Ile Lys 
    1415                 1420                 1425             


Gln Val  Val Lys Glu His Leu  Glu Asp Phe Glu Met  Leu Ser Phe 
    1430                 1435                 1440             


Trp Leu  Ser Asn Thr Cys His  Phe Leu Asn Cys Leu  Lys Gln Tyr 
    1445                 1450                 1455             


Ser Gly  Glu Glu Glu Phe Met  Lys His Asn Ser Pro  Gln Gln Asn 
    1460                 1465                 1470             


Lys Asn  Cys Leu Asn Asn Phe  Asp Leu Ser Glu Tyr  Arg Gln Ile 
    1475                 1480                 1485             


Leu Ser  Asp Val Ala Ile Arg  Ile Tyr His Gln Phe  Ile Ile Ile 
    1490                 1495                 1500             


Met Glu  Lys Asn Ile Gln Pro  Ile Ile Val Pro Gly  Met Leu Glu 
    1505                 1510                 1515             


Tyr Glu  Ser Leu Gln Gly Ile  Ser Gly Leu Lys Pro  Thr Gly Phe 
    1520                 1525                 1530             


Arg Lys  Arg Ser Ser Ser Ile  Asp Asp Thr Asp Gly  Tyr Thr Met 
    1535                 1540                 1545             


Thr Ser  Val Leu Gln Gln Leu  Ser Tyr Phe Tyr Thr  Thr Met Cys 
    1550                 1555                 1560             


Gln Asn  Gly Leu Asp Pro Glu  Leu Val Arg Gln Ala  Val Lys Gln 
    1565                 1570                 1575             


Leu Phe  Phe Leu Ile Gly Ala  Val Thr Leu Asn Ser  Leu Phe Leu 
    1580                 1585                 1590             


Arg Lys  Asp Met Cys Ser Cys  Arg Lys Gly Met Gln  Ile Arg Cys 
    1595                 1600                 1605             


Asn Ile  Ser Tyr Leu Glu Glu  Trp Leu Lys Asp Lys  Asn Leu Gln 
    1610                 1615                 1620             


Asn Ser  Leu Ala Lys Glu Thr  Leu Glu Pro Leu Ser  Gln Ala Ala 
    1625                 1630                 1635             


Trp Leu  Leu Gln Val Lys Lys  Thr Thr Asp Ser Asp  Ala Lys Glu 
    1640                 1645                 1650             


Ile Tyr  Glu Arg Cys Thr Ser  Leu Ser Ala Val Gln  Ile Ile Lys 
    1655                 1660                 1665             


Ile Leu  Asn Ser Tyr Thr Pro  Ile Asp Asp Phe Glu  Lys Arg Val 
    1670                 1675                 1680             


Thr Pro  Ser Phe Val Arg Lys  Val Gln Ala Leu Leu  Asn Ser Arg 
    1685                 1690                 1695             


Glu Asp  Ser Ser Gln Leu Met  Leu Asp Thr Lys Tyr  Leu Phe Gln 
    1700                 1705                 1710             


Val Thr  Phe Pro Phe Thr Pro  Ser Pro His Ala Leu  Glu Met Ile 
    1715                 1720                 1725             


Gln Ile  Pro Ser Ser Phe Lys  Leu Gly Phe Leu Asn  Arg Leu 
    1730                 1735                 1740         


<210>  4306
<211>  476
<212>  PRT
<213>  homo sapiens

<400>  4306

Met Met Thr Ala Lys Ala Val Asp Lys Ile Pro Val Thr Leu Ser Gly 
1               5                   10                  15      


Phe Val His Gln Leu Ser Asp Asn Ile Tyr Pro Val Glu Asp Leu Ala 
            20                  25                  30          


Ala Thr Ser Val Thr Ile Phe Pro Asn Ala Glu Leu Gly Gly Pro Phe 
        35                  40                  45              


Asp Gln Met Asn Gly Val Ala Gly Asp Gly Met Ile Asn Ile Asp Met 
    50                  55                  60                  


Thr Gly Glu Lys Arg Ser Leu Asp Leu Pro Tyr Pro Ser Ser Phe Ala 
65                  70                  75                  80  


Pro Val Ser Ala Pro Arg Asn Gln Thr Phe Thr Tyr Met Gly Lys Phe 
                85                  90                  95      


Ser Ile Asp Pro Gln Tyr Pro Gly Ala Ser Cys Tyr Pro Glu Gly Ile 
            100                 105                 110         


Ile Asn Ile Val Ser Ala Gly Ile Leu Gln Gly Val Thr Ser Pro Ala 
        115                 120                 125             


Ser Thr Thr Ala Ser Ser Ser Val Thr Ser Ala Ser Pro Asn Pro Leu 
    130                 135                 140                 


Ala Thr Gly Pro Leu Gly Val Cys Thr Met Ser Gln Thr Gln Pro Asp 
145                 150                 155                 160 


Leu Asp His Leu Tyr Ser Pro Pro Pro Pro Pro Pro Pro Tyr Ser Gly 
                165                 170                 175     


Cys Ala Gly Asp Leu Tyr Gln Asp Pro Ser Ala Phe Leu Ser Ala Ala 
            180                 185                 190         


Thr Thr Ser Thr Ser Ser Ser Leu Ala Tyr Pro Pro Pro Pro Ser Tyr 
        195                 200                 205             


Pro Ser Pro Lys Pro Ala Thr Asp Pro Gly Leu Phe Pro Met Ile Pro 
    210                 215                 220                 


Asp Tyr Pro Gly Phe Phe Pro Ser Gln Cys Gln Arg Asp Leu His Gly 
225                 230                 235                 240 


Thr Ala Gly Pro Asp Arg Lys Pro Phe Pro Cys Pro Leu Asp Thr Leu 
                245                 250                 255     


Arg Val Pro Pro Pro Leu Thr Pro Leu Ser Thr Ile Arg Asn Phe Thr 
            260                 265                 270         


Leu Gly Gly Pro Ser Ala Gly Val Thr Gly Pro Gly Ala Ser Gly Gly 
        275                 280                 285             


Ser Glu Gly Pro Arg Leu Pro Gly Ser Ser Ser Ala Ala Ala Ala Ala 
    290                 295                 300                 


Ala Ala Ala Ala Ala Tyr Asn Pro His His Leu Pro Leu Arg Pro Ile 
305                 310                 315                 320 


Leu Arg Pro Arg Lys Tyr Pro Asn Arg Pro Ser Lys Thr Pro Val His 
                325                 330                 335     


Glu Arg Pro Tyr Pro Cys Pro Ala Glu Gly Cys Asp Arg Arg Phe Ser 
            340                 345                 350         


Arg Ser Asp Glu Leu Thr Arg His Ile Arg Ile His Thr Gly His Lys 
        355                 360                 365             


Pro Phe Gln Cys Arg Ile Cys Met Arg Asn Phe Ser Arg Ser Asp His 
    370                 375                 380                 


Leu Thr Thr His Ile Arg Thr His Thr Gly Glu Lys Pro Phe Ala Cys 
385                 390                 395                 400 


Asp Tyr Cys Gly Arg Lys Phe Ala Arg Ser Asp Glu Arg Lys Arg His 
                405                 410                 415     


Thr Lys Ile His Leu Arg Gln Lys Glu Arg Lys Ser Ser Ala Pro Ser 
            420                 425                 430         


Ala Ser Val Pro Ala Pro Ser Thr Ala Ser Cys Ser Gly Gly Val Gln 
        435                 440                 445             


Pro Gly Gly Thr Leu Cys Ser Ser Asn Ser Ser Ser Leu Gly Gly Gly 
    450                 455                 460                 


Pro Leu Ala Pro Cys Ser Ser Arg Thr Arg Thr Pro 
465                 470                 475     


<210>  4307
<211>  217
<212>  PRT
<213>  homo sapiens

<400>  4307

Met Thr Ser Ser Tyr Gly His Val Leu Glu Arg Gln Pro Ala Leu Gly 
1               5                   10                  15      


Gly Arg Leu Asp Ser Pro Gly Asn Leu Asp Thr Leu Gln Ala Lys Lys 
            20                  25                  30          


Asn Phe Ser Val Ser His Leu Leu Asp Leu Glu Glu Ala Gly Asp Met 
        35                  40                  45              


Val Ala Ala Gln Ala Asp Glu Asn Val Gly Glu Ala Gly Arg Ser Leu 
    50                  55                  60                  


Leu Glu Ser Pro Gly Leu Thr Ser Gly Ser Asp Thr Pro Gln Gln Asp 
65                  70                  75                  80  


Asn Asp Gln Leu Asn Ser Glu Glu Lys Lys Lys Arg Lys Gln Arg Arg 
                85                  90                  95      


Asn Arg Thr Thr Phe Asn Ser Ser Gln Leu Gln Ala Leu Glu Arg Val 
            100                 105                 110         


Phe Glu Arg Thr His Tyr Pro Asp Ala Phe Val Arg Glu Asp Leu Ala 
        115                 120                 125             


Arg Arg Val Asn Leu Thr Glu Ala Arg Val Gln Val Trp Phe Gln Asn 
    130                 135                 140                 


Arg Arg Ala Lys Phe Arg Arg Asn Glu Arg Ala Met Leu Ala Asn Lys 
145                 150                 155                 160 


Asn Ala Ser Leu Leu Lys Ser Tyr Ser Gly Asp Val Thr Ala Val Glu 
                165                 170                 175     


Gln Pro Ile Val Pro Arg Pro Ala Pro Arg Pro Thr Asp Tyr Leu Ser 
            180                 185                 190         


Trp Gly Thr Ala Ser Pro Tyr Arg Ser Ser Ser Leu Pro Arg Cys Cys 
        195                 200                 205             


Leu His Glu Gly Leu His Asn Gly Phe 
    210                 215         


<210>  4308
<211>  735
<212>  PRT
<213>  homo sapiens

<400>  4308

Met Glu Gly Ala Gly Gly Ala Asn Asp Lys Lys Lys Ile Ser Ser Glu 
1               5                   10                  15      


Arg Arg Lys Glu Lys Ser Arg Asp Ala Ala Arg Ser Arg Arg Ser Lys 
            20                  25                  30          


Glu Ser Glu Val Phe Tyr Glu Leu Ala His Gln Leu Pro Leu Pro His 
        35                  40                  45              


Asn Val Ser Ser His Leu Asp Lys Ala Ser Val Met Arg Leu Thr Ile 
    50                  55                  60                  


Ser Tyr Leu Arg Val Arg Lys Leu Leu Asp Ala Gly Asp Leu Asp Ile 
65                  70                  75                  80  


Glu Asp Asp Met Lys Ala Gln Met Asn Cys Phe Tyr Leu Lys Ala Leu 
                85                  90                  95      


Asp Gly Phe Val Met Val Leu Thr Asp Asp Gly Asp Met Ile Tyr Ile 
            100                 105                 110         


Ser Asp Asn Val Asn Lys Tyr Met Gly Leu Thr Gln Phe Glu Leu Thr 
        115                 120                 125             


Gly His Ser Val Phe Asp Phe Thr His Pro Cys Asp His Glu Glu Met 
    130                 135                 140                 


Arg Glu Met Leu Thr His Arg Asn Gly Leu Val Lys Lys Gly Lys Glu 
145                 150                 155                 160 


Gln Asn Thr Gln Arg Ser Phe Phe Leu Arg Met Lys Cys Thr Leu Thr 
                165                 170                 175     


Ser Arg Gly Arg Thr Met Asn Ile Lys Ser Ala Thr Trp Lys Val Leu 
            180                 185                 190         


His Cys Thr Gly His Ile His Val Tyr Asp Thr Asn Ser Asn Gln Pro 
        195                 200                 205             


Gln Cys Gly Tyr Lys Lys Pro Pro Met Thr Cys Leu Val Leu Ile Cys 
    210                 215                 220                 


Glu Pro Ile Pro His Pro Ser Asn Ile Glu Ile Pro Leu Asp Ser Lys 
225                 230                 235                 240 


Thr Phe Leu Ser Arg His Ser Leu Asp Met Lys Phe Ser Tyr Cys Asp 
                245                 250                 255     


Glu Arg Ile Thr Glu Leu Met Gly Tyr Glu Pro Glu Glu Leu Leu Gly 
            260                 265                 270         


Arg Ser Ile Tyr Glu Tyr Tyr His Ala Leu Asp Ser Asp His Leu Thr 
        275                 280                 285             


Lys Thr His His Asp Met Phe Thr Lys Gly Gln Val Thr Thr Gly Gln 
    290                 295                 300                 


Tyr Arg Met Leu Ala Lys Arg Gly Gly Tyr Val Trp Val Glu Thr Gln 
305                 310                 315                 320 


Ala Thr Val Ile Tyr Asn Thr Lys Asn Ser Gln Pro Gln Cys Ile Val 
                325                 330                 335     


Cys Val Asn Tyr Val Val Ser Gly Ile Ile Gln His Asp Leu Ile Phe 
            340                 345                 350         


Ser Leu Gln Gln Thr Glu Cys Val Leu Lys Pro Val Glu Ser Ser Asp 
        355                 360                 365             


Met Lys Met Thr Gln Leu Phe Thr Lys Val Glu Ser Glu Asp Thr Ser 
    370                 375                 380                 


Ser Leu Phe Asp Lys Leu Lys Lys Glu Pro Asp Ala Leu Thr Leu Leu 
385                 390                 395                 400 


Ala Pro Ala Ala Gly Asp Thr Ile Ile Ser Leu Asp Phe Gly Ser Asn 
                405                 410                 415     


Asp Thr Glu Thr Asp Asp Gln Gln Leu Glu Glu Val Pro Leu Tyr Asn 
            420                 425                 430         


Asp Val Met Leu Pro Ser Pro Asn Glu Lys Leu Gln Asn Ile Asn Leu 
        435                 440                 445             


Ala Met Ser Pro Leu Pro Thr Ala Glu Thr Pro Lys Pro Leu Arg Ser 
    450                 455                 460                 


Ser Ala Asp Pro Ala Leu Asn Gln Glu Val Ala Leu Lys Leu Glu Pro 
465                 470                 475                 480 


Asn Pro Glu Ser Leu Glu Leu Ser Phe Thr Met Pro Gln Ile Gln Asp 
                485                 490                 495     


Gln Thr Pro Ser Pro Ser Asp Gly Ser Thr Arg Gln Ser Ser Pro Glu 
            500                 505                 510         


Pro Asn Ser Pro Ser Glu Tyr Cys Phe Tyr Val Asp Ser Asp Met Val 
        515                 520                 525             


Asn Glu Phe Lys Leu Glu Leu Val Glu Lys Leu Phe Ala Glu Asp Thr 
    530                 535                 540                 


Glu Ala Lys Asn Pro Phe Ser Thr Gln Asp Thr Asp Leu Asp Leu Glu 
545                 550                 555                 560 


Met Leu Ala Pro Tyr Ile Pro Met Asp Asp Asp Phe Gln Leu Arg Ser 
                565                 570                 575     


Phe Asp Gln Leu Ser Pro Leu Glu Ser Ser Ser Ala Ser Pro Glu Ser 
            580                 585                 590         


Ala Ser Pro Gln Ser Thr Val Thr Val Phe Gln Gln Thr Gln Ile Gln 
        595                 600                 605             


Glu Pro Thr Ala Asn Ala Thr Thr Thr Thr Ala Thr Thr Asp Glu Leu 
    610                 615                 620                 


Lys Thr Val Thr Lys Asp Arg Met Glu Asp Ile Lys Ile Leu Ile Ala 
625                 630                 635                 640 


Ser Pro Ser Pro Thr His Ile His Lys Glu Thr Thr Ser Ala Thr Ser 
                645                 650                 655     


Ser Pro Tyr Arg Asp Thr Gln Ser Arg Thr Ala Ser Pro Asn Arg Ala 
            660                 665                 670         


Gly Lys Gly Val Ile Glu Gln Thr Glu Lys Ser His Pro Arg Ser Pro 
        675                 680                 685             


Asn Val Leu Ser Val Ala Leu Ser Gln Arg Thr Thr Val Pro Glu Glu 
    690                 695                 700                 


Glu Leu Asn Pro Lys Ile Leu Ala Leu Gln Asn Ala Gln Arg Lys Arg 
705                 710                 715                 720 


Lys Met Glu His Asp Gly Ser Leu Phe Gln Ala Val Gly Ile Ile 
                725                 730                 735 


<210>  4309
<211>  316
<212>  PRT
<213>  homo sapiens

<400>  4309

Met Ser Asp Ala Ser Leu Arg Ser Thr Ser Thr Met Glu Arg Leu Val 
1               5                   10                  15      


Ala Arg Gly Thr Phe Pro Val Leu Val Arg Thr Ser Ala Cys Arg Ser 
            20                  25                  30          


Leu Phe Gly Pro Val Asp His Glu Glu Leu Ser Arg Glu Leu Gln Ala 
        35                  40                  45              


Arg Leu Ala Glu Leu Asn Ala Glu Asp Gln Asn Arg Trp Asp Tyr Asp 
    50                  55                  60                  


Phe Gln Gln Asp Met Pro Leu Arg Gly Pro Gly Arg Leu Gln Trp Thr 
65                  70                  75                  80  


Glu Val Asp Ser Asp Ser Val Pro Ala Phe Tyr Arg Glu Thr Val Gln 
                85                  90                  95      


Val Gly Arg Cys Arg Leu Leu Leu Ala Pro Arg Pro Val Ala Val Ala 
            100                 105                 110         


Val Ala Val Ser Pro Pro Leu Glu Pro Ala Ala Glu Ser Leu Asp Gly 
        115                 120                 125             


Leu Glu Glu Ala Pro Glu Gln Leu Pro Ser Val Pro Val Pro Ala Pro 
    130                 135                 140                 


Ala Ser Thr Pro Pro Pro Val Pro Val Leu Ala Pro Ala Pro Ala Pro 
145                 150                 155                 160 


Ala Pro Ala Pro Val Ala Ala Pro Val Ala Ala Pro Val Ala Val Ala 
                165                 170                 175     


Val Leu Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro 
            180                 185                 190         


Ala Pro Val Ala Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro 
        195                 200                 205             


Ala Pro Ala Pro Ala Pro Ala Pro Asp Ala Ala Pro Gln Glu Ser Ala 
    210                 215                 220                 


Glu Gln Gly Ala Asn Gln Gly Gln Arg Gly Gln Glu Pro Leu Ala Asp 
225                 230                 235                 240 


Gln Leu His Ser Gly Ile Ser Gly Arg Pro Ala Ala Gly Thr Ala Ala 
                245                 250                 255     


Ala Ser Ala Asn Gly Ala Ala Ile Lys Lys Leu Ser Gly Pro Leu Ile 
            260                 265                 270         


Ser Asp Phe Phe Ala Lys Arg Lys Arg Ser Ala Pro Glu Lys Ser Ser 
        275                 280                 285             


Gly Asp Val Pro Ala Pro Cys Pro Ser Pro Ser Ala Ala Pro Gly Val 
    290                 295                 300                 


Gly Ser Val Glu Gln Thr Pro Arg Lys Arg Leu Arg 
305                 310                 315     


<210>  4310
<211>  589
<212>  PRT
<213>  homo sapiens

<400>  4310

Met Ala Ala Ala Asp Gly Asp Asp Ser Leu Tyr Pro Ile Ala Val Leu 
1               5                   10                  15      


Ile Asp Glu Leu Arg Asn Glu Asp Val Gln Leu Arg Leu Asn Ser Ile 
            20                  25                  30          


Lys Lys Leu Ser Thr Ile Ala Leu Ala Leu Gly Val Glu Arg Thr Arg 
        35                  40                  45              


Ser Glu Leu Leu Pro Phe Leu Thr Asp Thr Ile Tyr Asp Glu Asp Glu 
    50                  55                  60                  


Val Leu Leu Ala Leu Ala Glu Gln Leu Gly Thr Phe Thr Thr Leu Val 
65                  70                  75                  80  


Gly Gly Pro Glu Tyr Val His Cys Leu Leu Pro Pro Leu Glu Ser Leu 
                85                  90                  95      


Ala Thr Val Glu Glu Thr Val Val Arg Asp Lys Ala Val Glu Ser Leu 
            100                 105                 110         


Arg Ala Ile Ser His Glu His Ser Pro Ser Asp Leu Glu Ala His Phe 
        115                 120                 125             


Val Pro Leu Val Lys Arg Leu Ala Gly Gly Asp Trp Phe Thr Ser Arg 
    130                 135                 140                 


Thr Ser Ala Cys Gly Leu Phe Ser Val Cys Tyr Pro Arg Val Ser Ser 
145                 150                 155                 160 


Ala Val Lys Ala Glu Leu Arg Gln Tyr Phe Arg Asn Leu Cys Ser Asp 
                165                 170                 175     


Asp Thr Pro Met Val Arg Arg Ala Ala Ala Ser Lys Leu Gly Glu Phe 
            180                 185                 190         


Ala Lys Val Leu Glu Leu Asp Asn Val Lys Ser Glu Ile Ile Pro Met 
        195                 200                 205             


Phe Ser Asn Leu Ala Ser Asp Glu Gln Asp Ser Val Arg Leu Leu Ala 
    210                 215                 220                 


Val Glu Ala Cys Val Asn Ile Ala Gln Leu Leu Pro Gln Glu Asp Leu 
225                 230                 235                 240 


Glu Ala Leu Val Met Pro Thr Leu Arg Gln Ala Ala Glu Asp Lys Ser 
                245                 250                 255     


Trp Arg Val Arg Tyr Met Val Ala Asp Lys Phe Thr Glu Leu Gln Lys 
            260                 265                 270         


Ala Val Gly Pro Glu Ile Thr Lys Thr Asp Leu Val Pro Ala Phe Gln 
        275                 280                 285             


Asn Leu Met Lys Asp Cys Glu Ala Glu Val Arg Ala Ala Ala Ser His 
    290                 295                 300                 


Lys Val Lys Glu Phe Cys Glu Asn Leu Ser Ala Asp Cys Arg Glu Asn 
305                 310                 315                 320 


Val Ile Met Ser Gln Ile Leu Pro Cys Ile Lys Glu Leu Val Ser Asp 
                325                 330                 335     


Ala Asn Gln His Val Lys Ser Ala Leu Ala Ser Val Ile Met Gly Leu 
            340                 345                 350         


Ser Pro Ile Leu Gly Lys Asp Asn Thr Ile Glu His Leu Leu Pro Leu 
        355                 360                 365             


Phe Leu Ala Gln Leu Lys Asp Glu Cys Pro Glu Val Arg Leu Asn Ile 
    370                 375                 380                 


Ile Ser Asn Leu Asp Cys Val Asn Glu Val Ile Gly Ile Arg Gln Leu 
385                 390                 395                 400 


Ser Gln Ser Leu Leu Pro Ala Ile Val Glu Leu Ala Glu Asp Ala Lys 
                405                 410                 415     


Trp Arg Val Arg Leu Ala Ile Ile Glu Tyr Met Pro Leu Leu Ala Gly 
            420                 425                 430         


Gln Leu Gly Val Glu Phe Phe Asp Glu Lys Leu Asn Ser Leu Cys Met 
        435                 440                 445             


Ala Trp Leu Val Asp His Val Tyr Ala Ile Arg Glu Ala Ala Thr Ser 
    450                 455                 460                 


Asn Leu Lys Lys Leu Val Glu Lys Phe Gly Lys Glu Trp Ala His Ala 
465                 470                 475                 480 


Thr Ile Ile Pro Lys Val Leu Ala Met Ser Gly Asp Pro Asn Tyr Leu 
                485                 490                 495     


His Arg Met Thr Thr Leu Phe Cys Ile Asn Val Leu Ser Glu Val Cys 
            500                 505                 510         


Gly Gln Asp Ile Thr Thr Lys His Met Leu Pro Thr Val Leu Arg Met 
        515                 520                 525             


Ala Gly Asp Pro Val Ala Asn Val Arg Phe Asn Val Ala Lys Ser Leu 
    530                 535                 540                 


Gln Lys Ile Gly Pro Ile Leu Asp Asn Ser Thr Leu Gln Ser Glu Val 
545                 550                 555                 560 


Lys Pro Ile Leu Glu Lys Leu Thr Gln Asp Gln Asp Val Asp Val Lys 
                565                 570                 575     


Tyr Phe Ala Gln Glu Ala Leu Thr Val Leu Ser Leu Ala 
            580                 585                 


<210>  4311
<211>  132
<212>  PRT
<213>  homo sapiens

<400>  4311

Met Lys Ala Glu Gly Gly Asp His Ser Met Ile Asn Leu Ser Val Gln 
1               5                   10                  15      


Gln Val Leu Ser Leu Trp Ala His Gly Thr Val Leu Arg Asn Leu Thr 
            20                  25                  30          


Glu Met Trp Tyr Trp Ile Phe Leu Trp Ala Leu Phe Ser Ser Leu Phe 
        35                  40                  45              


Val His Gly Ala Ala Gly Val Leu Met Phe Val Met Leu Gln Arg His 
    50                  55                  60                  


Arg Gln Gly Arg Val Ile Ser Val Ile Ala Val Ser Ile Gly Phe Leu 
65                  70                  75                  80  


Ala Ser Val Thr Gly Ala Met Ile Thr Ser Ala Ala Val Ala Gly Ile 
                85                  90                  95      


Tyr Arg Val Ala Gly Lys Asn Met Ala Pro Leu Glu Ala Leu Val Trp 
            100                 105                 110         


Gly Val Gly Gln Thr Val Leu Thr Leu Ile Ile Ser Phe Ser Arg Ile 
        115                 120                 125             


Leu Ala Thr Leu 
    130         


<210>  4312
<211>  503
<212>  PRT
<213>  homo sapiens

<400>  4312

Met Pro Val Pro Pro Pro Pro Ala Pro Pro Pro Pro Pro Thr Phe Ala 
1               5                   10                  15      


Leu Ala Asn Thr Glu Lys Pro Thr Leu Asn Lys Thr Glu Gln Ala Gly 
            20                  25                  30          


Arg Asn Ala Leu Leu Ser Asp Ile Ser Lys Gly Lys Lys Leu Lys Lys 
        35                  40                  45              


Thr Val Thr Asn Asp Arg Ser Ala Pro Ile Leu Asp Lys Pro Lys Gly 
    50                  55                  60                  


Ala Gly Ala Gly Gly Gly Gly Gly Gly Phe Gly Gly Gly Gly Gly Phe 
65                  70                  75                  80  


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ser Phe Gly Gly Gly Gly 
                85                  90                  95      


Pro Pro Gly Leu Gly Gly Leu Phe Gln Ala Gly Met Pro Lys Leu Arg 
            100                 105                 110         


Ser Thr Ala Asn Arg Asp Asn Asp Ser Gly Gly Ser Arg Pro Pro Leu 
        115                 120                 125             


Leu Pro Pro Gly Gly Arg Ser Thr Ser Ala Lys Pro Phe Ser Pro Pro 
    130                 135                 140                 


Ser Gly Pro Gly Arg Phe Pro Val Pro Ser Pro Gly His Arg Ser Gly 
145                 150                 155                 160 


Pro Pro Glu Pro Gln Arg Asn Arg Met Pro Pro Pro Arg Pro Asp Val 
                165                 170                 175     


Gly Ser Lys Pro Asp Ser Ile Pro Pro Pro Val Pro Ser Thr Pro Arg 
            180                 185                 190         


Pro Ile Gln Ser Ser Pro His Asn Arg Gly Ser Pro Pro Val Pro Gly 
        195                 200                 205             


Gly Pro Arg Gln Pro Ser Pro Gly Pro Thr Pro Pro Pro Phe Pro Gly 
    210                 215                 220                 


Asn Arg Gly Thr Ala Leu Gly Gly Gly Ser Ile Arg Gln Ser Pro Leu 
225                 230                 235                 240 


Ser Ser Ser Ser Pro Phe Ser Asn Arg Pro Pro Leu Pro Pro Thr Pro 
                245                 250                 255     


Ser Arg Ala Leu Asp Asp Lys Pro Pro Pro Pro Pro Pro Pro Val Gly 
            260                 265                 270         


Asn Arg Pro Ser Ile His Arg Glu Ala Val Pro Pro Pro Pro Pro Gln 
        275                 280                 285             


Asn Asn Lys Pro Pro Val Pro Ser Thr Pro Arg Pro Ser Ala Ser Ser 
    290                 295                 300                 


Gln Ala Pro Pro Pro Pro Pro Pro Pro Ser Arg Pro Gly Pro Pro Pro 
305                 310                 315                 320 


Leu Pro Pro Ser Ser Ser Gly Asn Asp Glu Thr Pro Arg Leu Pro Gln 
                325                 330                 335     


Arg Asn Leu Ser Leu Ser Ser Ser Thr Pro Pro Leu Pro Ser Pro Gly 
            340                 345                 350         


Arg Ser Gly Pro Leu Pro Pro Pro Pro Ser Glu Arg Pro Pro Pro Pro 
        355                 360                 365             


Val Arg Asp Pro Pro Gly Arg Ser Gly Pro Leu Pro Pro Pro Pro Pro 
    370                 375                 380                 


Val Ser Arg Asn Gly Ser Thr Ser Arg Ala Leu Pro Ala Thr Pro Gln 
385                 390                 395                 400 


Leu Pro Ser Arg Ser Gly Val Asp Ser Pro Arg Ser Gly Pro Arg Pro 
                405                 410                 415     


Pro Leu Pro Pro Asp Arg Pro Ser Ala Gly Ala Pro Pro Pro Pro Pro 
            420                 425                 430         


Pro Ser Thr Ser Ile Arg Asn Gly Phe Gln Asp Ser Pro Cys Glu Asp 
        435                 440                 445             


Glu Trp Glu Ser Arg Phe Tyr Phe His Pro Ile Ser Asp Leu Pro Pro 
    450                 455                 460                 


Pro Glu Pro Tyr Val Gln Thr Thr Lys Ser Tyr Pro Ser Lys Leu Ala 
465                 470                 475                 480 


Arg Asn Glu Ser Arg Ser Gly Ser Asn Arg Arg Glu Arg Gly Ala Pro 
                485                 490                 495     


Pro Leu Pro Pro Ile Pro Arg 
            500             


<210>  4313
<211>  911
<212>  PRT
<213>  homo sapiens

<400>  4313

Met Ala Gln Leu Phe Leu Pro Leu Leu Ala Ala Leu Val Leu Ala Gln 
1               5                   10                  15      


Ala Pro Ala Ala Leu Ala Asp Val Leu Glu Gly Asp Ser Ser Glu Asp 
            20                  25                  30          


Arg Ala Phe Arg Val Arg Ile Ala Gly Asp Ala Pro Leu Gln Gly Val 
        35                  40                  45              


Leu Gly Gly Ala Leu Thr Ile Pro Cys His Val His Tyr Leu Arg Pro 
    50                  55                  60                  


Pro Pro Ser Arg Arg Ala Val Leu Gly Ser Pro Arg Val Lys Trp Thr 
65                  70                  75                  80  


Phe Leu Ser Arg Gly Arg Glu Ala Glu Val Leu Val Ala Arg Gly Val 
                85                  90                  95      


Arg Val Lys Val Asn Glu Ala Tyr Arg Phe Arg Val Ala Leu Pro Ala 
            100                 105                 110         


Tyr Pro Ala Ser Leu Thr Asp Val Ser Leu Ala Leu Ser Glu Leu Arg 
        115                 120                 125             


Pro Asn Asp Ser Gly Ile Tyr Arg Cys Glu Val Gln His Gly Ile Asp 
    130                 135                 140                 


Asp Ser Ser Asp Ala Val Glu Val Lys Val Lys Gly Val Val Phe Leu 
145                 150                 155                 160 


Tyr Arg Glu Gly Ser Ala Arg Tyr Ala Phe Ser Phe Ser Gly Ala Gln 
                165                 170                 175     


Glu Ala Cys Ala Arg Ile Gly Ala His Ile Ala Thr Pro Glu Gln Leu 
            180                 185                 190         


Tyr Ala Ala Tyr Leu Gly Gly Tyr Glu Gln Cys Asp Ala Gly Trp Leu 
        195                 200                 205             


Ser Asp Gln Thr Val Arg Tyr Pro Ile Gln Thr Pro Arg Glu Ala Cys 
    210                 215                 220                 


Tyr Gly Asp Met Asp Gly Phe Pro Gly Val Arg Asn Tyr Gly Val Val 
225                 230                 235                 240 


Asp Pro Asp Asp Leu Tyr Asp Val Tyr Cys Tyr Ala Glu Asp Leu Asn 
                245                 250                 255     


Gly Glu Leu Phe Leu Gly Asp Pro Pro Glu Lys Leu Thr Leu Glu Glu 
            260                 265                 270         


Ala Arg Ala Tyr Cys Gln Glu Arg Gly Ala Glu Ile Ala Thr Thr Gly 
        275                 280                 285             


Gln Leu Tyr Ala Ala Trp Asp Gly Gly Leu Asp His Cys Ser Pro Gly 
    290                 295                 300                 


Trp Leu Ala Asp Gly Ser Val Arg Tyr Pro Ile Val Thr Pro Ser Gln 
305                 310                 315                 320 


Arg Cys Gly Gly Gly Leu Pro Gly Val Lys Thr Leu Phe Leu Phe Pro 
                325                 330                 335     


Asn Gln Thr Gly Phe Pro Asn Lys His Ser Arg Phe Asn Val Tyr Cys 
            340                 345                 350         


Phe Arg Asp Ser Ala Gln Pro Ser Ala Ile Pro Glu Ala Ser Asn Pro 
        355                 360                 365             


Ala Ser Asn Pro Ala Ser Asp Gly Leu Glu Ala Ile Val Thr Val Thr 
    370                 375                 380                 


Glu Thr Leu Glu Glu Leu Gln Leu Pro Gln Glu Ala Thr Glu Ser Glu 
385                 390                 395                 400 


Ser Arg Gly Ala Ile Tyr Ser Ile Pro Ile Met Glu Asp Gly Gly Gly 
                405                 410                 415     


Gly Ser Ser Thr Pro Glu Asp Pro Ala Glu Ala Pro Arg Thr Leu Leu 
            420                 425                 430         


Glu Phe Glu Thr Gln Ser Met Val Pro Pro Thr Gly Phe Ser Glu Glu 
        435                 440                 445             


Glu Gly Lys Ala Leu Glu Glu Glu Glu Lys Tyr Glu Asp Glu Glu Glu 
    450                 455                 460                 


Lys Glu Glu Glu Glu Glu Glu Glu Glu Val Glu Asp Glu Ala Leu Trp 
465                 470                 475                 480 


Ala Trp Pro Ser Glu Leu Ser Ser Pro Gly Pro Glu Ala Ser Leu Pro 
                485                 490                 495     


Thr Glu Pro Ala Ala Gln Glu Glu Ser Leu Ser Gln Ala Pro Ala Arg 
            500                 505                 510         


Ala Val Leu Gln Pro Gly Ala Ser Pro Leu Pro Asp Gly Glu Ser Glu 
        515                 520                 525             


Ala Ser Arg Pro Pro Arg Val His Gly Pro Pro Thr Glu Thr Leu Pro 
    530                 535                 540                 


Thr Pro Arg Glu Arg Asn Leu Ala Ser Pro Ser Pro Ser Thr Leu Val 
545                 550                 555                 560 


Glu Ala Arg Glu Val Gly Glu Ala Thr Gly Gly Pro Glu Leu Ser Gly 
                565                 570                 575     


Val Pro Arg Gly Glu Ser Glu Glu Thr Gly Ser Ser Glu Gly Ala Pro 
            580                 585                 590         


Ser Leu Leu Pro Ala Thr Arg Ala Pro Glu Gly Thr Arg Glu Leu Glu 
        595                 600                 605             


Ala Pro Ser Glu Asp Asn Ser Gly Arg Thr Ala Pro Ala Gly Thr Ser 
    610                 615                 620                 


Val Gln Ala Gln Pro Val Leu Pro Thr Asp Ser Ala Ser Arg Gly Gly 
625                 630                 635                 640 


Val Ala Val Val Pro Ala Ser Gly Asp Cys Val Pro Ser Pro Cys His 
                645                 650                 655     


Asn Gly Gly Thr Cys Leu Glu Glu Glu Glu Gly Val Arg Cys Leu Cys 
            660                 665                 670         


Leu Pro Gly Tyr Gly Gly Asp Leu Cys Asp Val Gly Leu Arg Phe Cys 
        675                 680                 685             


Asn Pro Gly Trp Asp Ala Phe Gln Gly Ala Cys Tyr Lys His Phe Ser 
    690                 695                 700                 


Thr Arg Arg Ser Trp Glu Glu Ala Glu Thr Gln Cys Arg Met Tyr Gly 
705                 710                 715                 720 


Ala His Leu Ala Ser Ile Ser Thr Pro Glu Glu Gln Asp Phe Ile Asn 
                725                 730                 735     


Asn Arg Tyr Arg Glu Tyr Gln Trp Ile Gly Leu Asn Asp Arg Thr Ile 
            740                 745                 750         


Glu Gly Asp Phe Leu Trp Ser Asp Gly Val Pro Leu Leu Tyr Glu Asn 
        755                 760                 765             


Trp Asn Pro Gly Gln Pro Asp Ser Tyr Phe Leu Ser Gly Glu Asn Cys 
    770                 775                 780                 


Val Val Met Val Trp His Asp Gln Gly Gln Trp Ser Asp Val Pro Cys 
785                 790                 795                 800 


Asn Tyr His Leu Ser Tyr Thr Cys Lys Met Gly Leu Val Ser Cys Gly 
                805                 810                 815     


Pro Pro Pro Glu Leu Pro Leu Ala Gln Val Phe Gly Arg Pro Arg Leu 
            820                 825                 830         


Arg Tyr Glu Val Asp Thr Val Leu Arg Tyr Arg Cys Arg Glu Gly Leu 
        835                 840                 845             


Ala Gln Arg Asn Leu Pro Leu Ile Arg Cys Gln Glu Asn Gly Arg Trp 
    850                 855                 860                 


Glu Ala Pro Gln Ile Ser Cys Val Pro Arg Arg Pro Ala Arg Ala Leu 
865                 870                 875                 880 


His Pro Glu Glu Asp Pro Glu Gly Arg Gln Gly Arg Leu Leu Gly Arg 
                885                 890                 895     


Trp Lys Ala Leu Leu Ile Pro Pro Ser Ser Pro Met Pro Gly Pro 
            900                 905                 910     


<210>  4314
<211>  434
<212>  PRT
<213>  homo sapiens

<400>  4314

Met Gly Met Gly Arg Gly Ala Gly Arg Ser Ala Leu Gly Phe Trp Pro 
1               5                   10                  15      


Thr Leu Ala Phe Leu Leu Cys Ser Phe Pro Ala Ala Thr Ser Pro Cys 
            20                  25                  30          


Lys Ile Leu Lys Cys Asn Ser Glu Phe Trp Ser Ala Thr Ser Gly Ser 
        35                  40                  45              


His Ala Pro Ala Ser Asp Asp Thr Pro Glu Phe Cys Ala Ala Leu Arg 
    50                  55                  60                  


Ser Tyr Ala Leu Cys Thr Arg Arg Thr Ala Arg Thr Cys Arg Gly Asp 
65                  70                  75                  80  


Leu Ala Tyr His Ser Ala Val His Gly Ile Glu Asp Leu Met Ser Gln 
                85                  90                  95      


His Asn Cys Ser Lys Asp Gly Pro Thr Ser Gln Pro Arg Leu Arg Thr 
            100                 105                 110         


Leu Pro Pro Ala Gly Asp Ser Gln Glu Arg Ser Asp Ser Pro Glu Ile 
        115                 120                 125             


Cys His Tyr Glu Lys Ser Phe His Lys His Ser Ala Thr Pro Asn Tyr 
    130                 135                 140                 


Thr His Cys Gly Leu Phe Gly Asp Pro His Leu Arg Thr Phe Thr Asp 
145                 150                 155                 160 


Arg Phe Gln Thr Cys Lys Val Gln Gly Ala Trp Pro Leu Ile Asp Asn 
                165                 170                 175     


Asn Tyr Leu Asn Val Gln Val Thr Asn Thr Pro Val Leu Pro Gly Ser 
            180                 185                 190         


Ala Ala Thr Ala Thr Ser Lys Leu Thr Ile Ile Phe Lys Asn Phe Gln 
        195                 200                 205             


Glu Cys Val Asp Gln Lys Val Tyr Gln Ala Glu Met Asp Glu Leu Pro 
    210                 215                 220                 


Ala Ala Phe Val Asp Gly Ser Lys Asn Gly Gly Asp Lys His Gly Ala 
225                 230                 235                 240 


Asn Ser Leu Lys Ile Thr Glu Lys Val Ser Gly Gln His Val Glu Ile 
                245                 250                 255     


Gln Ala Lys Tyr Ile Gly Thr Thr Ile Val Val Arg Gln Val Gly Arg 
            260                 265                 270         


Tyr Leu Thr Phe Ala Val Arg Met Pro Glu Glu Val Val Asn Ala Val 
        275                 280                 285             


Glu Asp Trp Asp Ser Gln Gly Leu Tyr Leu Cys Leu Arg Gly Cys Pro 
    290                 295                 300                 


Leu Asn Gln Gln Ile Asp Phe Gln Ala Phe His Thr Asn Ala Glu Gly 
305                 310                 315                 320 


Thr Gly Ala Arg Arg Leu Ala Ala Ala Ser Pro Ala Pro Thr Ala Pro 
                325                 330                 335     


Glu Thr Phe Pro Tyr Glu Thr Ala Val Ala Lys Cys Lys Glu Lys Leu 
            340                 345                 350         


Pro Val Glu Asp Leu Tyr Tyr Gln Ala Cys Val Phe Asp Leu Leu Thr 
        355                 360                 365             


Thr Gly Asp Val Asn Phe Thr Leu Ala Ala Tyr Tyr Ala Leu Glu Asp 
    370                 375                 380                 


Val Lys Met Leu His Ser Asn Lys Asp Lys Leu His Leu Tyr Glu Arg 
385                 390                 395                 400 


Thr Arg Asp Leu Pro Gly Arg Ala Ala Ala Gly Leu Pro Leu Ala Pro 
                405                 410                 415     


Arg Pro Leu Leu Gly Ala Leu Val Pro Leu Leu Ala Leu Leu Pro Val 
            420                 425                 430         


Phe Cys 
        


<210>  4315
<211>  450
<212>  PRT
<213>  homo sapiens

<400>  4315

Met Asp Pro Gly Asn Glu Asn Ser Ala Thr Glu Ala Ala Ala Ile Ile 
1               5                   10                  15      


Asp Leu Asp Pro Asp Phe Glu Pro Gln Ser Arg Pro Arg Ser Cys Thr 
            20                  25                  30          


Trp Pro Leu Pro Arg Pro Glu Ile Ala Asn Gln Pro Ser Glu Pro Pro 
        35                  40                  45              


Glu Val Glu Pro Asp Leu Gly Glu Lys Ala Ile Glu Ser Ala Pro Glu 
    50                  55                  60                  


Lys Arg Leu Thr Leu Ala Gln Ile Tyr Glu Trp Met Val Arg Thr Val 
65                  70                  75                  80  


Pro Tyr Phe Lys Asp Lys Gly Asp Ser Asn Ser Ser Ala Gly Trp Lys 
                85                  90                  95      


Asn Ser Ile Arg His Asn Leu Ser Leu His Ser Lys Phe Ile Lys Val 
            100                 105                 110         


His Asn Glu Ala Thr Gly Lys Ser Ser Trp Trp Met Leu Asn Pro Glu 
        115                 120                 125             


Gly Gly Lys Ser Gly Lys Ala Pro Arg Arg Arg Ala Ala Ser Met Asp 
    130                 135                 140                 


Ser Ser Ser Lys Leu Leu Arg Gly Arg Ser Lys Ala Pro Lys Lys Lys 
145                 150                 155                 160 


Pro Ser Val Leu Pro Ala Pro Pro Glu Gly Ala Thr Pro Thr Ser Pro 
                165                 170                 175     


Val Gly His Phe Ala Lys Trp Ser Gly Ser Pro Cys Ser Arg Asn Arg 
            180                 185                 190         


Glu Glu Ala Asp Met Trp Thr Thr Phe Arg Pro Arg Ser Ser Ser Asn 
        195                 200                 205             


Ala Ser Ser Val Ser Thr Arg Leu Ser Pro Leu Arg Pro Glu Ser Glu 
    210                 215                 220                 


Val Leu Ala Glu Glu Ile Pro Ala Ser Val Ser Ser Tyr Ala Gly Gly 
225                 230                 235                 240 


Val Pro Pro Thr Leu Asn Glu Gly Leu Glu Leu Leu Asp Gly Leu Asn 
                245                 250                 255     


Leu Thr Ser Ser His Ser Leu Leu Ser Arg Ser Gly Leu Ser Gly Phe 
            260                 265                 270         


Ser Leu Gln His Pro Gly Val Thr Gly Pro Leu His Thr Tyr Ser Ser 
        275                 280                 285             


Ser Leu Phe Ser Pro Ala Glu Gly Pro Leu Ser Ala Gly Glu Gly Cys 
    290                 295                 300                 


Phe Ser Ser Ser Gln Ala Leu Glu Ala Leu Leu Thr Ser Asp Thr Pro 
305                 310                 315                 320 


Pro Pro Pro Ala Asp Val Leu Met Thr Gln Val Asp Pro Ile Leu Ser 
                325                 330                 335     


Gln Ala Pro Thr Leu Leu Leu Leu Gly Gly Leu Pro Ser Ser Ser Lys 
            340                 345                 350         


Leu Ala Thr Gly Val Gly Leu Cys Pro Lys Pro Leu Glu Ala Pro Gly 
        355                 360                 365             


Pro Ser Ser Leu Val Pro Thr Leu Ser Met Ile Ala Pro Pro Pro Val 
    370                 375                 380                 


Met Ala Ser Ala Pro Ile Pro Lys Ala Leu Gly Thr Pro Val Leu Thr 
385                 390                 395                 400 


Pro Pro Thr Glu Ala Ala Ser Gln Asp Arg Met Pro Gln Asp Leu Asp 
                405                 410                 415     


Leu Asp Met Tyr Met Glu Asn Leu Glu Cys Asp Met Asp Asn Ile Ile 
            420                 425                 430         


Ser Asp Leu Met Asp Glu Gly Glu Gly Leu Asp Phe Asn Phe Glu Pro 
        435                 440                 445             


Asp Pro 
    450 


<210>  4316
<211>  135
<212>  PRT
<213>  homo sapiens

<400>  4316

Met Met Leu Ser Pro Asp Gln Ala Ala Asp Ser Asp His Pro Ser Ser 
1               5                   10                  15      


Ala His Ser Asp Pro Glu Ser Leu Gly Gly Thr Asp Thr Lys Val Leu 
            20                  25                  30          


Gly Ser Val Ser Asp Leu Glu Pro Val Glu Glu Ala Glu Gly Asp Gly 
        35                  40                  45              


Lys Gly Gly Ser Arg Ala Ala Leu Tyr Pro His Pro Gln Gln Leu Ser 
    50                  55                  60                  


Arg Glu Glu Lys Arg Arg Arg Arg Arg Ala Thr Ala Lys Tyr Arg Ser 
65                  70                  75                  80  


Ala His Ala Thr Arg Glu Arg Ile Arg Val Glu Ala Phe Asn Leu Ala 
                85                  90                  95      


Phe Ala Glu Leu Arg Lys Leu Leu Pro Thr Leu Pro Pro Asp Lys Lys 
            100                 105                 110         


Leu Ser Lys Ile Glu Ile Leu Arg Leu Ala Ile Cys Tyr Ile Ser Tyr 
        115                 120                 125             


Leu Asn His Val Leu Asp Val 
    130                 135 


<210>  4317
<211>  168
<212>  PRT
<213>  homo sapiens

<400>  4317

Met Ala Glu Pro Trp Gly Asn Glu Leu Ala Ser Ala Ala Ala Arg Gly 
1               5                   10                  15      


Asp Leu Glu Gln Leu Thr Ser Leu Leu Gln Asn Asn Val Asn Val Asn 
            20                  25                  30          


Ala Gln Asn Gly Phe Gly Arg Thr Ala Leu Gln Val Met Lys Leu Gly 
        35                  40                  45              


Asn Pro Glu Ile Ala Arg Arg Leu Leu Leu Arg Gly Ala Asn Pro Asp 
    50                  55                  60                  


Leu Lys Asp Arg Thr Gly Phe Ala Val Ile His Asp Ala Ala Arg Ala 
65                  70                  75                  80  


Gly Phe Leu Asp Thr Leu Gln Thr Leu Leu Glu Phe Gln Ala Asp Val 
                85                  90                  95      


Asn Ile Glu Asp Asn Glu Gly Asn Leu Pro Leu His Leu Ala Ala Lys 
            100                 105                 110         


Glu Gly His Leu Arg Val Val Glu Phe Leu Val Lys His Thr Ala Ser 
        115                 120                 125             


Asn Val Gly His Arg Asn His Lys Gly Asp Thr Ala Cys Asp Leu Ala 
    130                 135                 140                 


Arg Leu Tyr Gly Arg Asn Glu Val Val Ser Leu Met Gln Ala Asn Gly 
145                 150                 155                 160 


Ala Gly Gly Ala Thr Asn Leu Gln 
                165             


<210>  4318
<211>  288
<212>  PRT
<213>  homo sapiens

<400>  4318

Met Ala Glu Lys Arg His Thr Arg Asp Ser Glu Ala Gln Arg Leu Pro 
1               5                   10                  15      


Asp Ser Phe Lys Asp Ser Pro Ser Lys Gly Leu Gly Pro Cys Gly Trp 
            20                  25                  30          


Ile Leu Val Ala Phe Ser Phe Leu Phe Thr Val Ile Thr Phe Pro Ile 
        35                  40                  45              


Ser Ile Trp Met Cys Ile Lys Ile Ile Lys Glu Tyr Glu Arg Ala Ile 
    50                  55                  60                  


Ile Phe Arg Leu Gly Arg Ile Leu Gln Gly Gly Ala Lys Gly Pro Gly 
65                  70                  75                  80  


Leu Phe Phe Ile Leu Pro Cys Thr Asp Ser Phe Ile Lys Val Asp Met 
                85                  90                  95      


Arg Thr Ile Ser Phe Asp Ile Pro Pro Gln Glu Ile Leu Thr Lys Asp 
            100                 105                 110         


Ser Val Thr Ile Ser Val Asp Gly Val Val Tyr Tyr Arg Val Gln Asn 
        115                 120                 125             


Ala Thr Leu Ala Val Ala Asn Ile Thr Asn Ala Asp Ser Ala Thr Arg 
    130                 135                 140                 


Leu Leu Ala Gln Thr Thr Leu Arg Asn Val Leu Gly Thr Lys Asn Leu 
145                 150                 155                 160 


Ser Gln Ile Leu Ser Asp Arg Glu Glu Ile Ala His Asn Met Gln Ser 
                165                 170                 175     


Thr Leu Asp Asp Ala Thr Asp Ala Trp Gly Ile Lys Val Glu Arg Val 
            180                 185                 190         


Glu Ile Lys Asp Val Lys Leu Pro Val Gln Leu Gln Arg Ala Met Ala 
        195                 200                 205             


Ala Glu Ala Glu Ala Ser Arg Glu Ala Arg Ala Lys Val Ile Ala Ala 
    210                 215                 220                 


Glu Gly Glu Met Asn Ala Ser Arg Ala Leu Lys Glu Ala Ser Met Val 
225                 230                 235                 240 


Ile Thr Glu Ser Pro Ala Ala Leu Gln Leu Arg Tyr Leu Gln Thr Leu 
                245                 250                 255     


Thr Thr Ile Ala Ala Glu Lys Asn Ser Thr Ile Val Phe Pro Leu Pro 
            260                 265                 270         


Ile Asp Met Leu Gln Gly Ile Ile Gly Ala Lys His Ser His Leu Gly 
        275                 280                 285             


<210>  4319
<211>  643
<212>  PRT
<213>  homo sapiens

<400>  4319

Met Leu Glu Asn Tyr Gly Asn Val Ala Ser Leu Gly Phe Pro Leu Leu 
1               5                   10                  15      


Lys Pro Ala Val Ile Ser Gln Leu Glu Gly Gly Ser Glu Leu Gly Gly 
            20                  25                  30          


Ser Ser Pro Leu Ala Ala Gly Thr Gly Leu Gln Gly Leu Gln Thr Asp 
        35                  40                  45              


Ile Gln Thr Asp Asn Asp Leu Thr Lys Glu Met Tyr Glu Gly Lys Glu 
    50                  55                  60                  


Asn Val Ser Phe Glu Leu Gln Arg Asp Phe Ser Gln Glu Thr Asp Phe 
65                  70                  75                  80  


Ser Glu Ala Ser Leu Leu Glu Lys Gln Gln Glu Val His Ser Ala Gly 
                85                  90                  95      


Asn Ile Lys Lys Glu Lys Ser Asn Thr Ile Asp Gly Thr Val Lys Asp 
            100                 105                 110         


Glu Thr Ser Pro Val Glu Glu Cys Phe Phe Ser Gln Ser Ser Asn Ser 
        115                 120                 125             


Tyr Gln Cys His Thr Ile Thr Gly Glu Gln Pro Ser Gly Cys Thr Gly 
    130                 135                 140                 


Leu Gly Lys Ser Ile Ser Phe Asp Thr Lys Leu Val Lys His Glu Ile 
145                 150                 155                 160 


Ile Asn Ser Glu Glu Arg Pro Phe Lys Cys Glu Glu Leu Val Glu Pro 
                165                 170                 175     


Phe Arg Cys Asp Ser Gln Leu Ile Gln His Gln Glu Asn Asn Thr Glu 
            180                 185                 190         


Glu Lys Pro Tyr Gln Cys Ser Glu Cys Gly Lys Ala Phe Ser Ile Asn 
        195                 200                 205             


Glu Lys Leu Ile Trp His Gln Arg Leu His Ser Gly Glu Lys Pro Phe 
    210                 215                 220                 


Lys Cys Val Glu Cys Gly Lys Ser Phe Ser Tyr Ser Ser His Tyr Ile 
225                 230                 235                 240 


Thr His Gln Thr Ile His Ser Gly Glu Lys Pro Tyr Gln Cys Lys Met 
                245                 250                 255     


Cys Gly Lys Ala Phe Ser Val Asn Gly Ser Leu Ser Arg His Gln Arg 
            260                 265                 270         


Ile His Thr Gly Glu Lys Pro Tyr Gln Cys Lys Glu Cys Gly Asn Gly 
        275                 280                 285             


Phe Ser Cys Ser Ser Ala Tyr Ile Thr His Gln Arg Val His Thr Gly 
    290                 295                 300                 


Glu Lys Pro Tyr Glu Cys Asn Asp Cys Gly Lys Ala Phe Asn Val Asn 
305                 310                 315                 320 


Ala Lys Leu Ile Gln His Gln Arg Ile His Thr Gly Glu Lys Pro Tyr 
                325                 330                 335     


Glu Cys Asn Glu Cys Gly Lys Gly Phe Arg Cys Ser Ser Gln Leu Arg 
            340                 345                 350         


Gln His Gln Ser Ile His Thr Gly Glu Lys Pro Tyr Gln Cys Lys Glu 
        355                 360                 365             


Cys Gly Lys Gly Phe Asn Asn Asn Thr Lys Leu Ile Gln His Gln Arg 
    370                 375                 380                 


Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Thr Glu Cys Gly Lys Ala 
385                 390                 395                 400 


Phe Ser Val Lys Gly Lys Leu Ile Gln His Gln Arg Ile His Thr Gly 
                405                 410                 415     


Glu Lys Pro Tyr Glu Cys Asn Glu Cys Gly Lys Ala Phe Arg Cys Asn 
            420                 425                 430         


Ser Gln Phe Arg Gln His Leu Arg Ile His Thr Gly Glu Lys Pro Tyr 
        435                 440                 445             


Glu Cys Asn Glu Cys Gly Lys Ala Phe Ser Val Asn Gly Lys Leu Met 
    450                 455                 460                 


Arg His Gln Arg Ile His Thr Gly Glu Lys Pro Phe Glu Cys Asn Glu 
465                 470                 475                 480 


Cys Gly Arg Cys Phe Thr Ser Lys Arg Asn Leu Leu Asp His His Arg 
                485                 490                 495     


Ile His Thr Gly Glu Lys Pro Tyr Gln Cys Lys Glu Cys Gly Lys Ala 
            500                 505                 510         


Phe Ser Ile Asn Ala Lys Leu Thr Arg His Gln Arg Ile His Thr Gly 
        515                 520                 525             


Glu Lys Pro Phe Lys Cys Met Glu Cys Glu Lys Ala Phe Ser Cys Ser 
    530                 535                 540                 


Ser Asn Tyr Ile Val His Gln Arg Ile His Thr Gly Glu Lys Pro Phe 
545                 550                 555                 560 


Gln Cys Lys Glu Cys Gly Lys Ala Phe His Val Asn Ala His Leu Ile 
                565                 570                 575     


Arg His Gln Arg Ser His Thr Gly Glu Lys Pro Phe Arg Cys Val Glu 
            580                 585                 590         


Cys Gly Lys Gly Phe Ser Phe Ser Ser Asp Tyr Ile Ile His Gln Thr 
        595                 600                 605             


Val His Thr Trp Lys Lys Pro Tyr Met Cys Ser Val Cys Gly Lys Ala 
    610                 615                 620                 


Phe Arg Phe Ser Phe Gln Leu Ser Gln His Gln Ser Val His Ser Glu 
625                 630                 635                 640 


Gly Lys Ser 
            


<210>  4320
<211>  137
<212>  PRT
<213>  homo sapiens

<400>  4320

Met Pro Asn Phe Ala Gly Thr Trp Lys Met Arg Ser Ser Glu Asn Phe 
1               5                   10                  15      


Asp Glu Leu Leu Lys Ala Leu Gly Val Asn Ala Met Leu Arg Lys Val 
            20                  25                  30          


Ala Val Ala Ala Ala Ser Lys Pro His Val Glu Ile Arg Gln Asp Gly 
        35                  40                  45              


Asp Gln Phe Tyr Ile Lys Thr Ser Thr Thr Val Arg Thr Thr Glu Ile 
    50                  55                  60                  


Asn Phe Lys Val Gly Glu Gly Phe Glu Glu Glu Thr Val Asp Gly Arg 
65                  70                  75                  80  


Lys Cys Arg Ser Leu Ala Thr Trp Glu Asn Glu Asn Lys Ile His Cys 
                85                  90                  95      


Thr Gln Thr Leu Leu Glu Gly Asp Gly Pro Lys Thr Tyr Trp Thr Arg 
            100                 105                 110         


Glu Leu Ala Asn Asp Glu Leu Ile Leu Thr Phe Gly Ala Asp Asp Val 
        115                 120                 125             


Val Cys Thr Arg Ile Tyr Val Arg Glu 
    130                 135         


<210>  4321
<211>  195
<212>  PRT
<213>  homo sapiens

<400>  4321

Met Ala Pro Ala Ala Ser Arg Leu Arg Ala Glu Ala Gly Leu Gly Ala 
1               5                   10                  15      


Leu Pro Arg Arg Ala Leu Ala Gln Tyr Leu Leu Phe Leu Arg Leu Tyr 
            20                  25                  30          


Pro Val Leu Thr Lys Ala Ala Thr Ser Gly Ile Leu Ser Ala Leu Gly 
        35                  40                  45              


Asn Phe Leu Ala Gln Met Ile Glu Lys Lys Arg Lys Lys Glu Asn Ser 
    50                  55                  60                  


Arg Ser Leu Asp Val Gly Gly Pro Leu Arg Tyr Ala Val Tyr Gly Phe 
65                  70                  75                  80  


Phe Phe Thr Gly Pro Leu Ser His Phe Phe Tyr Phe Phe Met Glu His 
                85                  90                  95      


Trp Ile Pro Pro Glu Val Pro Leu Ala Gly Leu Arg Arg Leu Leu Leu 
            100                 105                 110         


Asp Arg Leu Val Phe Ala Pro Ala Phe Leu Met Leu Phe Phe Leu Ile 
        115                 120                 125             


Met Asn Phe Leu Glu Gly Lys Asp Ala Ser Ala Phe Ala Ala Lys Met 
    130                 135                 140                 


Arg Gly Gly Phe Trp Pro Ala Leu Arg Met Asn Trp Arg Val Trp Thr 
145                 150                 155                 160 


Pro Leu Gln Phe Ile Asn Ile Asn Tyr Val Pro Leu Lys Phe Arg Val 
                165                 170                 175     


Leu Phe Ala Asn Leu Ala Ala Leu Phe Trp Tyr Ala Tyr Leu Ala Ser 
            180                 185                 190         


Leu Gly Lys 
        195 


<210>  4322
<211>  742
<212>  PRT
<213>  homo sapiens

<400>  4322

Met Glu Lys Leu Phe Cys Cys Phe Pro Asn Ser Met Val Val Glu His 
1               5                   10                  15      


Pro Glu Phe Leu Lys Ala Gly Lys Glu Pro Gly Leu Gln Ile Trp Arg 
            20                  25                  30          


Val Glu Lys Phe Asp Leu Val Pro Val Pro Thr Asn Leu Tyr Gly Asp 
        35                  40                  45              


Phe Phe Thr Gly Asp Ala Tyr Val Ile Leu Lys Thr Val Gln Leu Arg 
    50                  55                  60                  


Asn Gly Asn Leu Gln Tyr Asp Leu His Tyr Trp Leu Gly Asn Glu Cys 
65                  70                  75                  80  


Ser Gln Asp Glu Ser Gly Ala Ala Ala Ile Phe Thr Val Gln Leu Asp 
                85                  90                  95      


Asp Tyr Leu Asn Gly Arg Ala Val Gln His Arg Glu Val Gln Gly Phe 
            100                 105                 110         


Glu Ser Ala Thr Phe Leu Gly Tyr Phe Lys Ser Gly Leu Lys Tyr Lys 
        115                 120                 125             


Lys Gly Gly Val Ala Ser Gly Phe Lys His Val Val Pro Asn Glu Val 
    130                 135                 140                 


Val Val Gln Arg Leu Phe Gln Val Lys Gly Arg Arg Val Val Arg Ala 
145                 150                 155                 160 


Thr Glu Val Pro Val Ser Trp Glu Ser Phe Asn Asn Gly Asp Cys Phe 
                165                 170                 175     


Ile Leu Asp Leu Gly Asn Asn Ile His Gln Trp Cys Gly Ser Asn Ser 
            180                 185                 190         


Asn Arg Tyr Glu Arg Leu Lys Ala Thr Gln Val Ser Lys Gly Ile Arg 
        195                 200                 205             


Asp Asn Glu Arg Ser Gly Arg Ala Arg Val His Val Ser Glu Glu Gly 
    210                 215                 220                 


Thr Glu Pro Glu Ala Met Leu Gln Val Leu Gly Pro Lys Pro Ala Leu 
225                 230                 235                 240 


Pro Ala Gly Thr Glu Asp Thr Ala Lys Glu Asp Ala Ala Asn Arg Lys 
                245                 250                 255     


Leu Ala Lys Leu Tyr Lys Val Ser Asn Gly Ala Gly Thr Met Ser Val 
            260                 265                 270         


Ser Leu Val Ala Asp Glu Asn Pro Phe Ala Gln Gly Ala Leu Lys Ser 
        275                 280                 285             


Glu Asp Cys Phe Ile Leu Asp His Gly Lys Asp Gly Lys Ile Phe Val 
    290                 295                 300                 


Trp Lys Gly Lys Gln Ala Asn Thr Glu Glu Arg Lys Ala Ala Leu Lys 
305                 310                 315                 320 


Thr Ala Ser Asp Phe Ile Thr Lys Met Asp Tyr Pro Lys Gln Thr Gln 
                325                 330                 335     


Val Ser Val Leu Pro Glu Gly Gly Glu Thr Pro Leu Phe Lys Gln Phe 
            340                 345                 350         


Phe Lys Asn Trp Arg Asp Pro Asp Gln Thr Asp Gly Leu Gly Leu Ser 
        355                 360                 365             


Tyr Leu Ser Ser His Ile Ala Asn Val Glu Arg Val Pro Phe Asp Ala 
    370                 375                 380                 


Ala Thr Leu His Thr Ser Thr Ala Met Ala Ala Gln His Gly Met Asp 
385                 390                 395                 400 


Asp Asp Gly Thr Gly Gln Lys Gln Ile Trp Arg Ile Glu Gly Ser Asn 
                405                 410                 415     


Lys Val Pro Val Asp Pro Ala Thr Tyr Gly Gln Phe Tyr Gly Gly Asp 
            420                 425                 430         


Ser Tyr Ile Ile Leu Tyr Asn Tyr Arg His Gly Gly Arg Gln Gly Gln 
        435                 440                 445             


Ile Ile Tyr Asn Trp Gln Gly Ala Gln Ser Thr Gln Asp Glu Val Ala 
    450                 455                 460                 


Ala Ser Ala Ile Leu Thr Ala Gln Leu Asp Glu Glu Leu Gly Gly Thr 
465                 470                 475                 480 


Pro Val Gln Ser Arg Val Val Gln Gly Lys Glu Pro Ala His Leu Met 
                485                 490                 495     


Ser Leu Phe Gly Gly Lys Pro Met Ile Ile Tyr Lys Gly Gly Thr Ser 
            500                 505                 510         


Arg Glu Gly Gly Gln Thr Ala Pro Ala Ser Thr Arg Leu Phe Gln Val 
        515                 520                 525             


Arg Ala Asn Ser Ala Gly Ala Thr Arg Ala Val Glu Val Leu Pro Lys 
    530                 535                 540                 


Ala Gly Ala Leu Asn Ser Asn Asp Ala Phe Val Leu Lys Thr Pro Ser 
545                 550                 555                 560 


Ala Ala Tyr Leu Trp Val Gly Thr Gly Ala Ser Glu Ala Glu Lys Thr 
                565                 570                 575     


Gly Ala Gln Glu Leu Leu Arg Val Leu Arg Ala Gln Pro Val Gln Val 
            580                 585                 590         


Ala Glu Gly Ser Glu Pro Asp Gly Phe Trp Glu Ala Leu Gly Gly Lys 
        595                 600                 605             


Ala Ala Tyr Arg Thr Ser Pro Arg Leu Lys Asp Lys Lys Met Asp Ala 
    610                 615                 620                 


His Pro Pro Arg Leu Phe Ala Cys Ser Asn Lys Ile Gly Arg Phe Val 
625                 630                 635                 640 


Ile Glu Glu Val Pro Gly Glu Leu Met Gln Glu Asp Leu Ala Thr Asp 
                645                 650                 655     


Asp Val Met Leu Leu Asp Thr Trp Asp Gln Val Phe Val Trp Val Gly 
            660                 665                 670         


Lys Asp Ser Gln Glu Glu Glu Lys Thr Glu Ala Leu Thr Ser Ala Lys 
        675                 680                 685             


Arg Tyr Ile Glu Thr Asp Pro Ala Asn Arg Asp Arg Arg Thr Pro Ile 
    690                 695                 700                 


Thr Val Val Lys Gln Gly Phe Glu Pro Pro Ser Phe Val Gly Trp Phe 
705                 710                 715                 720 


Leu Gly Trp Asp Asp Asp Tyr Trp Ser Val Asp Pro Leu Asp Arg Ala 
                725                 730                 735     


Met Ala Glu Leu Ala Ala 
            740         


<210>  4323
<211>  742
<212>  PRT
<213>  homo sapiens

<400>  4323

Met Glu Lys Leu Phe Cys Cys Phe Pro Asn Ser Met Val Val Glu His 
1               5                   10                  15      


Pro Glu Phe Leu Lys Ala Gly Lys Glu Pro Gly Leu Gln Ile Trp Arg 
            20                  25                  30          


Val Glu Lys Phe Asp Leu Val Pro Val Pro Thr Asn Leu Tyr Gly Asp 
        35                  40                  45              


Phe Phe Thr Gly Asp Ala Tyr Val Ile Leu Lys Thr Val Gln Leu Arg 
    50                  55                  60                  


Asn Gly Asn Leu Gln Tyr Asp Leu His Tyr Trp Leu Gly Asn Glu Cys 
65                  70                  75                  80  


Ser Gln Asp Glu Ser Gly Ala Ala Ala Ile Phe Thr Val Gln Leu Asp 
                85                  90                  95      


Asp Tyr Leu Asn Gly Arg Ala Val Gln His Arg Glu Val Gln Gly Phe 
            100                 105                 110         


Glu Ser Ala Thr Phe Leu Gly Tyr Phe Lys Ser Gly Leu Lys Tyr Lys 
        115                 120                 125             


Lys Gly Gly Val Ala Ser Gly Phe Lys His Val Val Pro Asn Glu Val 
    130                 135                 140                 


Val Val Gln Arg Leu Phe Gln Val Lys Gly Arg Arg Val Val Arg Ala 
145                 150                 155                 160 


Thr Glu Val Pro Val Ser Trp Glu Ser Phe Asn Asn Gly Asp Cys Phe 
                165                 170                 175     


Ile Leu Asp Leu Gly Asn Asn Ile His Gln Trp Cys Gly Ser Asn Ser 
            180                 185                 190         


Asn Arg Tyr Glu Arg Leu Lys Ala Thr Gln Val Ser Lys Gly Ile Arg 
        195                 200                 205             


Asp Asn Glu Arg Ser Gly Arg Ala Arg Val His Val Ser Glu Glu Gly 
    210                 215                 220                 


Thr Glu Pro Glu Ala Met Leu Gln Val Leu Gly Pro Lys Pro Ala Leu 
225                 230                 235                 240 


Pro Ala Gly Thr Glu Asp Thr Ala Lys Glu Asp Ala Ala Asn Arg Lys 
                245                 250                 255     


Leu Ala Lys Leu Tyr Lys Val Ser Asn Gly Ala Gly Thr Met Ser Val 
            260                 265                 270         


Ser Leu Val Ala Asp Glu Asn Pro Phe Ala Gln Gly Ala Leu Lys Ser 
        275                 280                 285             


Glu Asp Cys Phe Ile Leu Asp His Gly Lys Asp Gly Lys Ile Phe Val 
    290                 295                 300                 


Trp Lys Gly Lys Gln Ala Asn Thr Glu Glu Arg Lys Ala Ala Leu Lys 
305                 310                 315                 320 


Thr Ala Ser Asp Phe Ile Thr Lys Met Asp Tyr Pro Lys Gln Thr Gln 
                325                 330                 335     


Val Ser Val Leu Pro Glu Gly Gly Glu Thr Pro Leu Phe Lys Gln Phe 
            340                 345                 350         


Phe Lys Asn Trp Arg Asp Pro Asp Gln Thr Asp Gly Leu Gly Leu Ser 
        355                 360                 365             


Tyr Leu Ser Ser His Ile Ala Asn Val Glu Arg Val Pro Phe Asp Ala 
    370                 375                 380                 


Ala Thr Leu His Thr Ser Thr Ala Met Ala Ala Gln His Gly Met Asp 
385                 390                 395                 400 


Asp Asp Gly Thr Gly Gln Lys Gln Ile Trp Arg Ile Glu Gly Ser Asn 
                405                 410                 415     


Lys Val Pro Val Asp Pro Ala Thr Tyr Gly Gln Phe Tyr Gly Gly Asp 
            420                 425                 430         


Ser Tyr Ile Ile Leu Tyr Asn Tyr Arg His Gly Gly Arg Gln Gly Gln 
        435                 440                 445             


Ile Ile Tyr Asn Trp Gln Gly Ala Gln Ser Thr Gln Asp Glu Val Ala 
    450                 455                 460                 


Ala Ser Ala Ile Leu Thr Ala Gln Leu Asp Glu Glu Leu Gly Gly Thr 
465                 470                 475                 480 


Pro Val Gln Ser Arg Val Val Gln Gly Lys Glu Pro Ala His Leu Met 
                485                 490                 495     


Ser Leu Phe Gly Gly Lys Pro Met Ile Ile Tyr Lys Gly Gly Thr Ser 
            500                 505                 510         


Arg Glu Gly Gly Gln Thr Ala Pro Ala Ser Thr Arg Leu Phe Gln Val 
        515                 520                 525             


Arg Ala Asn Ser Ala Gly Ala Thr Arg Ala Val Glu Val Leu Pro Lys 
    530                 535                 540                 


Ala Gly Ala Leu Asn Ser Asn Asp Ala Phe Val Leu Lys Thr Pro Ser 
545                 550                 555                 560 


Ala Ala Tyr Leu Trp Val Gly Thr Gly Ala Ser Glu Ala Glu Lys Thr 
                565                 570                 575     


Gly Ala Gln Glu Leu Leu Arg Val Leu Arg Ala Gln Pro Val Gln Val 
            580                 585                 590         


Ala Glu Gly Ser Glu Pro Asp Gly Phe Trp Glu Ala Leu Gly Gly Lys 
        595                 600                 605             


Ala Ala Tyr Arg Thr Ser Pro Arg Leu Lys Asp Lys Lys Met Asp Ala 
    610                 615                 620                 


His Pro Pro Arg Leu Phe Ala Cys Ser Asn Lys Ile Gly Arg Phe Val 
625                 630                 635                 640 


Ile Glu Glu Val Pro Gly Glu Leu Met Gln Glu Asp Leu Ala Thr Asp 
                645                 650                 655     


Asp Val Met Leu Leu Asp Thr Trp Asp Gln Val Phe Val Trp Val Gly 
            660                 665                 670         


Lys Asp Ser Gln Glu Glu Glu Lys Thr Glu Ala Leu Thr Ser Ala Lys 
        675                 680                 685             


Arg Tyr Ile Glu Thr Asp Pro Ala Asn Arg Asp Arg Arg Thr Pro Ile 
    690                 695                 700                 


Thr Val Val Lys Gln Gly Phe Glu Pro Pro Ser Phe Val Gly Trp Phe 
705                 710                 715                 720 


Leu Gly Trp Asp Asp Asp Tyr Trp Ser Val Asp Pro Leu Asp Arg Ala 
                725                 730                 735     


Met Ala Glu Leu Ala Ala 
            740         


<210>  4324
<211>  501
<212>  PRT
<213>  homo sapiens

<400>  4324

Met Asn Leu Glu Gln Glu Arg Pro Phe Val Cys Ser Ala Pro Gly Cys 
1               5                   10                  15      


Ser Gln Arg Phe Pro Thr Glu Asp His Leu Met Ile His Arg His Lys 
            20                  25                  30          


His Glu Met Thr Leu Lys Phe Pro Ser Ile Lys Thr Asp Asn Met Leu 
        35                  40                  45              


Ser Asp Gln Thr Pro Thr Pro Thr Arg Phe Leu Lys Asn Cys Glu Glu 
    50                  55                  60                  


Val Gly Leu Phe Ser Glu Leu Asp Cys Ser Leu Glu His Glu Phe Arg 
65                  70                  75                  80  


Lys Ala Gln Glu Glu Glu Ser Ser Lys Arg Asn Ile Ser Met His Asn 
                85                  90                  95      


Ala Val Gly Gly Ala Met Thr Gly Pro Gly Thr His Gln Leu Ser Ser 
            100                 105                 110         


Ala Arg Leu Pro Asn His Asp Thr Asn Val Val Ile Gln Gln Ala Met 
        115                 120                 125             


Pro Ser Pro Gln Ser Ser Ser Val Ile Thr Gln Ala Pro Ser Thr Asn 
    130                 135                 140                 


Arg Gln Ile Gly Pro Val Pro Gly Ser Leu Ser Ser Leu Leu His Leu 
145                 150                 155                 160 


His Asn Arg Gln Arg Gln Pro Met Pro Ala Ser Met Pro Gly Thr Leu 
                165                 170                 175     


Pro Asn Pro Thr Met Pro Gly Ser Ser Ala Val Leu Met Pro Met Glu 
            180                 185                 190         


Arg Gln Met Ser Val Asn Ser Ser Ile Met Gly Met Gln Gly Pro Asn 
        195                 200                 205             


Leu Ser Asn Pro Cys Ala Ser Pro Gln Val Gln Pro Met His Ser Glu 
    210                 215                 220                 


Ala Lys Met Arg Leu Lys Ala Ala Leu Thr His His Pro Ala Ala Met 
225                 230                 235                 240 


Ser Asn Gly Asn Met Asn Thr Met Gly His Met Met Glu Met Met Gly 
                245                 250                 255     


Ser Arg Gln Asp Gln Thr Pro His His His Met His Ser His Pro His 
            260                 265                 270         


Gln His Gln Thr Leu Pro Pro His His Pro Tyr Pro His Gln His Gln 
        275                 280                 285             


His Pro Ala His His Pro His Pro Gln Pro His His Gln Gln Asn His 
    290                 295                 300                 


Pro His His His Ser His Ser His Leu His Ala His Pro Ala His His 
305                 310                 315                 320 


Gln Thr Ser Pro His Pro Pro Leu His Thr Gly Asn Gln Ala Gln Val 
                325                 330                 335     


Ser Pro Ala Thr Gln Gln Met Gln Pro Thr Gln Thr Ile Gln Pro Pro 
            340                 345                 350         


Gln Pro Thr Gly Gly Arg Arg Arg Arg Val Val Asp Glu Asp Pro Asp 
        355                 360                 365             


Glu Arg Arg Arg Lys Phe Leu Glu Arg Asn Arg Ala Ala Ala Thr Arg 
    370                 375                 380                 


Cys Arg Gln Lys Arg Lys Val Trp Val Met Ser Leu Glu Lys Lys Ala 
385                 390                 395                 400 


Glu Glu Leu Thr Gln Thr Asn Met Gln Leu Gln Asn Glu Val Ser Met 
                405                 410                 415     


Leu Lys Asn Glu Val Ala Gln Leu Lys Gln Leu Leu Leu Thr His Lys 
            420                 425                 430         


Asp Cys Pro Ile Thr Ala Met Gln Lys Glu Ser Gln Gly Tyr Leu Ser 
        435                 440                 445             


Pro Glu Ser Ser Pro Pro Ala Ser Pro Val Pro Ala Cys Ser Gln Gln 
    450                 455                 460                 


Gln Val Ile Gln His Asn Thr Ile Thr Thr Ser Ser Ser Val Ser Glu 
465                 470                 475                 480 


Val Val Gly Ser Ser Thr Leu Ser Gln Leu Thr Thr His Arg Thr Asp 
                485                 490                 495     


Leu Asn Pro Ile Leu 
            500     


<210>  4325
<211>  1690
<212>  PRT
<213>  homo sapiens

<400>  4325

Met His Pro Gly Leu Trp Leu Leu Leu Val Thr Leu Cys Leu Thr Glu 
1               5                   10                  15      


Glu Leu Ala Ala Ala Gly Glu Lys Ser Tyr Gly Lys Pro Cys Gly Gly 
            20                  25                  30          


Gln Asp Cys Ser Gly Ser Cys Gln Cys Phe Pro Glu Lys Gly Ala Arg 
        35                  40                  45              


Gly Arg Pro Gly Pro Ile Gly Ile Gln Gly Pro Thr Gly Pro Gln Gly 
    50                  55                  60                  


Phe Thr Gly Ser Thr Gly Leu Ser Gly Leu Lys Gly Glu Arg Gly Phe 
65                  70                  75                  80  


Pro Gly Leu Leu Gly Pro Tyr Gly Pro Lys Gly Asp Lys Gly Pro Met 
                85                  90                  95      


Gly Val Pro Gly Phe Leu Gly Ile Asn Gly Ile Pro Gly His Pro Gly 
            100                 105                 110         


Gln Pro Gly Pro Arg Gly Pro Pro Gly Leu Asp Gly Cys Asn Gly Thr 
        115                 120                 125             


Gln Gly Ala Val Gly Phe Pro Gly Pro Asp Gly Tyr Pro Gly Leu Leu 
    130                 135                 140                 


Gly Pro Pro Gly Leu Pro Gly Gln Lys Gly Ser Lys Gly Asp Pro Val 
145                 150                 155                 160 


Leu Ala Pro Gly Ser Phe Lys Gly Met Lys Gly Asp Pro Gly Leu Pro 
                165                 170                 175     


Gly Leu Asp Gly Ile Thr Gly Pro Gln Gly Ala Pro Gly Phe Pro Gly 
            180                 185                 190         


Ala Val Gly Pro Ala Gly Pro Pro Gly Leu Gln Gly Pro Pro Gly Pro 
        195                 200                 205             


Pro Gly Pro Leu Gly Pro Asp Gly Asn Met Gly Leu Gly Phe Gln Gly 
    210                 215                 220                 


Glu Lys Gly Val Lys Gly Asp Val Gly Leu Pro Gly Pro Ala Gly Pro 
225                 230                 235                 240 


Pro Pro Ser Thr Gly Glu Leu Glu Phe Met Gly Phe Pro Lys Gly Lys 
                245                 250                 255     


Lys Gly Ser Lys Gly Glu Pro Gly Pro Lys Gly Phe Pro Gly Ile Ser 
            260                 265                 270         


Gly Pro Pro Gly Phe Pro Gly Leu Gly Thr Thr Gly Glu Lys Gly Glu 
        275                 280                 285             


Lys Gly Glu Lys Gly Ile Pro Gly Leu Pro Gly Pro Arg Gly Pro Met 
    290                 295                 300                 


Gly Ser Glu Gly Val Gln Gly Pro Pro Gly Gln Gln Gly Lys Lys Gly 
305                 310                 315                 320 


Thr Leu Gly Phe Pro Gly Leu Asn Gly Phe Gln Gly Ile Glu Gly Gln 
                325                 330                 335     


Lys Gly Asp Ile Gly Leu Pro Gly Pro Asp Val Phe Ile Asp Ile Asp 
            340                 345                 350         


Gly Ala Val Ile Ser Gly Asn Pro Gly Asp Pro Gly Val Pro Gly Leu 
        355                 360                 365             


Pro Gly Leu Lys Gly Asp Glu Gly Ile Gln Gly Leu Arg Gly Pro Ser 
    370                 375                 380                 


Gly Val Pro Gly Leu Pro Ala Leu Ser Gly Val Pro Gly Ala Leu Gly 
385                 390                 395                 400 


Pro Gln Gly Phe Pro Gly Leu Lys Gly Asp Gln Gly Asn Pro Gly Arg 
                405                 410                 415     


Thr Thr Ile Gly Ala Ala Gly Leu Pro Gly Arg Asp Gly Leu Pro Gly 
            420                 425                 430         


Pro Pro Gly Pro Pro Gly Pro Pro Ser Pro Glu Phe Glu Thr Glu Thr 
        435                 440                 445             


Leu His Asn Lys Glu Ser Gly Phe Pro Gly Leu Arg Gly Glu Gln Gly 
    450                 455                 460                 


Pro Lys Gly Asn Leu Gly Leu Lys Gly Ile Lys Gly Asp Ser Gly Phe 
465                 470                 475                 480 


Cys Ala Cys Asp Gly Gly Val Pro Asn Thr Gly Pro Pro Gly Glu Pro 
                485                 490                 495     


Gly Pro Pro Gly Pro Trp Gly Leu Ile Gly Leu Pro Gly Leu Lys Gly 
            500                 505                 510         


Ala Arg Gly Asp Arg Gly Ser Gly Gly Ala Gln Gly Pro Ala Gly Ala 
        515                 520                 525             


Pro Gly Leu Val Gly Pro Leu Gly Pro Ser Gly Pro Lys Gly Lys Lys 
    530                 535                 540                 


Gly Glu Pro Ile Leu Ser Thr Ile Gln Gly Met Pro Gly Asp Arg Gly 
545                 550                 555                 560 


Asp Ser Gly Ser Gln Gly Phe Arg Gly Val Ile Gly Glu Pro Gly Lys 
                565                 570                 575     


Asp Gly Val Pro Gly Leu Pro Gly Leu Pro Gly Leu Pro Gly Asp Gly 
            580                 585                 590         


Gly Gln Gly Phe Pro Gly Glu Lys Gly Leu Pro Gly Leu Pro Gly Glu 
        595                 600                 605             


Lys Gly His Pro Gly Pro Pro Gly Leu Pro Gly Asn Gly Leu Pro Gly 
    610                 615                 620                 


Leu Pro Gly Pro Arg Gly Leu Pro Gly Asp Lys Gly Lys Asp Gly Leu 
625                 630                 635                 640 


Pro Gly Gln Gln Gly Leu Pro Gly Ser Lys Gly Ile Thr Leu Pro Cys 
                645                 650                 655     


Ile Ile Pro Gly Ser Tyr Gly Pro Ser Gly Phe Pro Gly Thr Pro Gly 
            660                 665                 670         


Phe Pro Gly Pro Lys Gly Ser Arg Gly Leu Pro Gly Thr Pro Gly Gln 
        675                 680                 685             


Pro Gly Ser Ser Gly Ser Lys Gly Glu Pro Gly Ser Pro Gly Leu Val 
    690                 695                 700                 


His Leu Pro Glu Leu Pro Gly Phe Pro Gly Pro Arg Gly Glu Lys Gly 
705                 710                 715                 720 


Leu Pro Gly Phe Pro Gly Leu Pro Gly Lys Asp Gly Leu Pro Gly Met 
                725                 730                 735     


Ile Gly Ser Pro Gly Leu Pro Gly Ser Lys Gly Ala Thr Gly Asp Ile 
            740                 745                 750         


Phe Gly Ala Glu Asn Gly Ala Pro Gly Glu Gln Gly Leu Gln Gly Leu 
        755                 760                 765             


Thr Gly His Lys Gly Phe Leu Gly Asp Ser Gly Leu Pro Gly Leu Lys 
    770                 775                 780                 


Gly Val His Gly Lys Pro Gly Leu Leu Gly Pro Lys Gly Glu Arg Gly 
785                 790                 795                 800 


Ser Pro Gly Thr Pro Gly Gln Val Gly Gln Pro Gly Thr Pro Gly Ser 
                805                 810                 815     


Ser Gly Pro Tyr Gly Ile Lys Gly Lys Ser Gly Leu Pro Gly Ala Pro 
            820                 825                 830         


Gly Phe Pro Gly Ile Ser Gly His Pro Gly Lys Lys Gly Thr Arg Gly 
        835                 840                 845             


Lys Lys Gly Pro Pro Gly Ser Ile Val Lys Lys Gly Leu Pro Gly Leu 
    850                 855                 860                 


Lys Gly Leu Pro Gly Asn Pro Gly Leu Val Gly Leu Lys Gly Ser Pro 
865                 870                 875                 880 


Gly Ser Pro Gly Val Ala Gly Leu Pro Ala Leu Ser Gly Pro Lys Gly 
                885                 890                 895     


Glu Lys Gly Ser Val Gly Phe Val Gly Phe Pro Gly Ile Pro Gly Leu 
            900                 905                 910         


Pro Gly Ile Pro Gly Thr Arg Gly Leu Lys Gly Ile Pro Gly Ser Thr 
        915                 920                 925             


Gly Lys Met Gly Pro Ser Gly Arg Ala Gly Thr Pro Gly Glu Lys Gly 
    930                 935                 940                 


Asp Arg Gly Asn Pro Gly Pro Val Gly Ile Pro Ser Pro Arg Arg Pro 
945                 950                 955                 960 


Met Ser Asn Leu Trp Leu Lys Gly Asp Lys Gly Ser Gln Gly Ser Ala 
                965                 970                 975     


Gly Ser Asn Gly Phe Pro Gly Pro Arg Gly Asp Lys Gly Glu Ala Gly 
            980                 985                 990         


Arg Pro Gly Pro Pro Gly Leu Pro  Gly Ala Pro Gly Leu  Pro Gly Ile 
        995                 1000                 1005             


Ile Lys  Gly Val Ser Gly Lys  Pro Gly Pro Pro Gly  Phe Met Gly 
    1010                 1015                 1020             


Ile Arg  Gly Leu Pro Gly Leu  Lys Gly Ser Ser Gly  Ile Thr Gly 
    1025                 1030                 1035             


Phe Pro  Gly Met Pro Gly Glu  Ser Gly Ser Gln Gly  Ile Arg Gly 
    1040                 1045                 1050             


Ser Pro  Gly Leu Pro Gly Ala  Ser Gly Leu Pro Gly  Leu Lys Gly 
    1055                 1060                 1065             


Asp Asn  Gly Gln Thr Val Glu  Ile Ser Gly Ser Pro  Gly Pro Lys 
    1070                 1075                 1080             


Gly Gln  Pro Gly Glu Ser Gly  Phe Lys Gly Thr Lys  Gly Arg Asp 
    1085                 1090                 1095             


Gly Leu  Ile Gly Asn Ile Gly  Phe Pro Gly Asn Lys  Gly Glu Asp 
    1100                 1105                 1110             


Gly Lys  Val Gly Val Ser Gly  Asp Val Gly Leu Pro  Gly Ala Pro 
    1115                 1120                 1125             


Gly Phe  Pro Gly Val Ala Gly  Met Arg Gly Glu Pro  Gly Leu Pro 
    1130                 1135                 1140             


Gly Ser  Ser Gly His Gln Gly  Ala Ile Gly Pro Leu  Gly Ser Pro 
    1145                 1150                 1155             


Gly Leu  Ile Gly Pro Lys Gly  Phe Pro Gly Phe Pro  Gly Leu His 
    1160                 1165                 1170             


Gly Leu  Asn Gly Leu Pro Gly  Thr Lys Gly Thr His  Gly Thr Pro 
    1175                 1180                 1185             


Gly Pro  Ser Ile Thr Gly Val  Pro Gly Pro Ala Gly  Leu Pro Gly 
    1190                 1195                 1200             


Pro Lys  Gly Glu Lys Gly Tyr  Pro Gly Ile Gly Ile  Gly Ala Pro 
    1205                 1210                 1215             


Gly Lys  Pro Gly Leu Arg Gly  Gln Lys Gly Asp Arg  Gly Phe Pro 
    1220                 1225                 1230             


Gly Leu  Gln Gly Pro Ala Gly  Leu Pro Gly Ala Pro  Gly Ile Ser 
    1235                 1240                 1245             


Leu Pro  Ser Leu Ile Ala Gly  Gln Pro Gly Asp Pro  Gly Arg Pro 
    1250                 1255                 1260             


Gly Leu  Asp Gly Glu Arg Gly  Arg Pro Gly Pro Ala  Gly Pro Pro 
    1265                 1270                 1275             


Gly Pro  Pro Gly Pro Ser Ser  Asn Gln Gly Asp Thr  Gly Asp Pro 
    1280                 1285                 1290             


Gly Phe  Pro Gly Ile Pro Gly  Pro Lys Gly Pro Lys  Gly Asp Gln 
    1295                 1300                 1305             


Gly Ile  Pro Gly Phe Ser Gly  Leu Pro Gly Glu Leu  Gly Leu Lys 
    1310                 1315                 1320             


Gly Met  Arg Gly Glu Pro Gly  Phe Met Gly Thr Pro  Gly Lys Val 
    1325                 1330                 1335             


Gly Pro  Pro Gly Asp Pro Gly  Phe Pro Gly Met Lys  Gly Lys Ala 
    1340                 1345                 1350             


Gly Pro  Arg Gly Ser Ser Gly  Leu Gln Gly Asp Pro  Gly Gln Thr 
    1355                 1360                 1365             


Pro Thr  Ala Glu Ala Val Gln  Val Pro Pro Gly Pro  Leu Gly Leu 
    1370                 1375                 1380             


Pro Gly  Ile Asp Gly Ile Pro  Gly Leu Thr Gly Asp  Pro Gly Ala 
    1385                 1390                 1395             


Gln Gly  Pro Val Gly Leu Gln  Gly Ser Lys Gly Leu  Pro Gly Ile 
    1400                 1405                 1410             


Pro Gly  Lys Asp Gly Pro Ser  Gly Leu Pro Gly Pro  Pro Gly Ala 
    1415                 1420                 1425             


Leu Gly  Asp Pro Gly Leu Pro  Gly Leu Gln Gly Pro  Pro Gly Phe 
    1430                 1435                 1440             


Glu Gly  Ala Pro Gly Gln Gln  Gly Pro Phe Gly Met  Pro Gly Met 
    1445                 1450                 1455             


Pro Gly  Gln Ser Met Arg Val  Gly Tyr Thr Leu Val  Lys His Ser 
    1460                 1465                 1470             


Gln Ser  Glu Gln Val Pro Pro  Cys Pro Ile Gly Met  Ser Gln Leu 
    1475                 1480                 1485             


Trp Val  Gly Tyr Ser Leu Leu  Phe Val Glu Gly Gln  Glu Lys Ala 
    1490                 1495                 1500             


His Asn  Gln Asp Leu Gly Phe  Ala Gly Ser Cys Leu  Pro Arg Phe 
    1505                 1510                 1515             


Ser Thr  Met Pro Phe Ile Tyr  Cys Asn Ile Asn Glu  Val Cys His 
    1520                 1525                 1530             


Tyr Ala  Arg Arg Asn Asp Lys  Ser Tyr Trp Leu Ser  Thr Thr Ala 
    1535                 1540                 1545             


Pro Ile  Pro Met Met Pro Val  Ser Gln Thr Gln Ile  Pro Gln Tyr 
    1550                 1555                 1560             


Ile Ser  Arg Cys Ser Val Cys  Glu Ala Pro Ser Gln  Ala Ile Ala 
    1565                 1570                 1575             


Val His  Ser Gln Asp Ile Thr  Ile Pro Gln Cys Pro  Leu Gly Trp 
    1580                 1585                 1590             


Arg Ser  Leu Trp Ile Gly Tyr  Ser Phe Leu Met His  Thr Ala Ala 
    1595                 1600                 1605             


Gly Ala  Glu Gly Gly Gly Gln  Ser Leu Val Ser Pro  Gly Ser Cys 
    1610                 1615                 1620             


Leu Glu  Asp Phe Arg Ala Thr  Pro Phe Ile Glu Cys  Ser Gly Ala 
    1625                 1630                 1635             


Arg Gly  Thr Cys His Tyr Phe  Ala Asn Lys Tyr Ser  Phe Trp Leu 
    1640                 1645                 1650             


Thr Thr  Val Glu Glu Arg Gln  Gln Phe Gly Glu Leu  Pro Val Ser 
    1655                 1660                 1665             


Glu Thr  Leu Lys Ala Gly Gln  Leu His Thr Arg Val  Ser Arg Cys 
    1670                 1675                 1680             


Gln Val  Cys Met Lys Ser Leu  
    1685                 1690 


<210>  4326
<211>  672
<212>  PRT
<213>  homo sapiens

<400>  4326

Met Glu Ser Arg Lys Leu Ile Ser Ala Thr Asp Ile Gln Tyr Ser Gly 
1               5                   10                  15      


Ser Leu Leu Asn Ser Leu Asn Glu Gln Arg Gly His Gly Leu Phe Cys 
            20                  25                  30          


Asp Val Thr Val Ile Val Glu Asp Arg Lys Phe Arg Ala His Lys Asn 
        35                  40                  45              


Ile Leu Ser Ala Ser Ser Thr Tyr Phe His Gln Leu Phe Ser Val Ala 
    50                  55                  60                  


Gly Gln Val Val Glu Leu Ser Phe Ile Arg Ala Glu Ile Phe Ala Glu 
65                  70                  75                  80  


Ile Leu Asn Tyr Ile Tyr Ser Ser Lys Ile Val Arg Val Arg Ser Asp 
                85                  90                  95      


Leu Leu Asp Glu Leu Ile Lys Ser Gly Gln Leu Leu Gly Val Lys Phe 
            100                 105                 110         


Ile Ala Glu Leu Gly Val Pro Leu Ser Gln Val Lys Ser Ile Ser Gly 
        115                 120                 125             


Thr Ala Gln Asp Gly Asn Thr Glu Pro Leu Pro Pro Asp Ser Gly Asp 
    130                 135                 140                 


Lys Asn Leu Val Ile Gln Lys Ser Lys Asp Glu Ala Gln Asp Asn Gly 
145                 150                 155                 160 


Ala Thr Ile Met Pro Ile Ile Thr Glu Ser Phe Ser Leu Ser Ala Glu 
                165                 170                 175     


Asp Tyr Glu Met Lys Lys Ile Ile Val Thr Asp Ser Asp Asp Asp Asp 
            180                 185                 190         


Asp Asp Val Ile Phe Cys Ser Glu Ile Leu Pro Thr Lys Glu Thr Leu 
        195                 200                 205             


Pro Ser Asn Asn Thr Val Ala Gln Val Gln Ser Asn Pro Gly Pro Val 
    210                 215                 220                 


Ala Ile Ser Asp Val Ala Pro Ser Ala Ser Asn Asn Ser Pro Pro Leu 
225                 230                 235                 240 


Thr Asn Ile Thr Pro Thr Gln Lys Leu Pro Thr Pro Val Asn Gln Ala 
                245                 250                 255     


Thr Leu Ser Gln Thr Gln Gly Ser Glu Lys Leu Leu Val Ser Ser Ala 
            260                 265                 270         


Pro Thr His Leu Thr Pro Asn Ile Ile Leu Leu Asn Gln Thr Pro Leu 
        275                 280                 285             


Ser Thr Pro Pro Asn Val Ser Ser Ser Leu Pro Asn His Met Pro Ser 
    290                 295                 300                 


Ser Ile Asn Leu Leu Val Gln Asn Gln Gln Thr Pro Asn Ser Ala Ile 
305                 310                 315                 320 


Leu Thr Gly Asn Lys Ala Asn Glu Glu Glu Glu Glu Glu Ile Ile Asp 
                325                 330                 335     


Asp Asp Asp Asp Thr Ile Ser Ser Ser Pro Asp Ser Ala Val Ser Asn 
            340                 345                 350         


Thr Ser Leu Val Pro Gln Ala Asp Thr Ser Gln Asn Thr Ser Phe Asp 
        355                 360                 365             


Gly Ser Leu Ile Gln Lys Met Gln Ile Pro Thr Leu Leu Gln Glu Pro 
    370                 375                 380                 


Leu Ser Asn Ser Leu Lys Ile Ser Asp Ile Ile Thr Arg Asn Thr Asn 
385                 390                 395                 400 


Asp Pro Gly Val Gly Ser Lys His Leu Met Glu Gly Gln Lys Ile Ile 
                405                 410                 415     


Thr Leu Asp Thr Ala Thr Glu Ile Glu Gly Leu Ser Thr Gly Cys Lys 
            420                 425                 430         


Val Tyr Ala Asn Ile Gly Glu Asp Thr Tyr Asp Ile Val Ile Pro Val 
        435                 440                 445             


Lys Asp Asp Pro Asp Glu Gly Glu Ala Arg Leu Glu Asn Glu Ile Pro 
    450                 455                 460                 


Lys Thr Ser Gly Ser Glu Met Ala Asn Lys Arg Met Lys Val Lys His 
465                 470                 475                 480 


Asp Asp His Tyr Glu Leu Ile Val Asp Gly Arg Val Tyr Tyr Ile Cys 
                485                 490                 495     


Ile Val Cys Lys Arg Ser Tyr Val Cys Leu Thr Ser Leu Arg Arg His 
            500                 505                 510         


Phe Asn Ile His Ser Trp Glu Lys Lys Tyr Pro Cys Arg Tyr Cys Glu 
        515                 520                 525             


Lys Val Phe Pro Leu Ala Glu Tyr Arg Thr Lys His Glu Ile His His 
    530                 535                 540                 


Thr Gly Glu Arg Arg Tyr Gln Cys Leu Ala Cys Gly Lys Ser Phe Ile 
545                 550                 555                 560 


Asn Tyr Gln Phe Met Ser Ser His Ile Lys Ser Val His Ser Gln Asp 
                565                 570                 575     


Pro Ser Gly Asp Ser Lys Leu Tyr Arg Leu His Pro Cys Arg Ser Leu 
            580                 585                 590         


Gln Ile Arg Gln Tyr Ala Tyr Leu Ser Asp Arg Ser Ser Thr Ile Pro 
        595                 600                 605             


Ala Met Lys Asp Asp Gly Ile Gly Tyr Lys Val Asp Thr Gly Lys Glu 
    610                 615                 620                 


Pro Pro Val Gly Thr Thr Thr Ser Thr Gln Asn Lys Pro Met Thr Trp 
625                 630                 635                 640 


Glu Asp Ile Phe Ile Gln Gln Glu Asn Asp Ser Ile Phe Lys Gln Asn 
                645                 650                 655     


Val Thr Asp Gly Ser Thr Glu Phe Glu Phe Ile Ile Pro Glu Ser Tyr 
            660                 665                 670         


<210>  4327
<211>  517
<212>  PRT
<213>  homo sapiens

<400>  4327

Met Gly Arg Arg Ala Leu Leu Leu Leu Leu Leu Ser Phe Leu Ala Pro 
1               5                   10                  15      


Trp Ala Thr Ile Ala Leu Arg Pro Ala Leu Arg Ala Leu Gly Ser Leu 
            20                  25                  30          


His Leu Pro Thr Asn Pro Thr Ser Leu Pro Ala Val Ala Lys Asn Tyr 
        35                  40                  45              


Ser Val Leu Tyr Phe Gln Gln Lys Ala Leu Ala Ala Gly Gln Leu His 
    50                  55                  60                  


Ile Cys Ile Ile Gln Leu Asn His Tyr Lys Thr Pro Leu Val Asp His 
65                  70                  75                  80  


Phe Gly Phe Asn Thr Val Lys Thr Phe Asn Gln Arg Tyr Leu Val Ala 
                85                  90                  95      


Asp Lys Tyr Trp Lys Lys Asn Gly Gly Ser Ile Leu Phe Tyr Thr Gly 
            100                 105                 110         


Asn Glu Gly Asp Ile Ile Trp Phe Cys Asn Asn Thr Gly Phe Met Trp 
        115                 120                 125             


Asp Val Ala Glu Glu Leu Lys Ala Met Leu Val Phe Ala Glu His Arg 
    130                 135                 140                 


Tyr Tyr Gly Glu Ser Leu Pro Phe Gly Asp Asn Ser Phe Lys Asp Ser 
145                 150                 155                 160 


Arg His Leu Asn Phe Leu Thr Ser Glu Gln Ala Leu Ala Asp Phe Ala 
                165                 170                 175     


Glu Leu Ile Lys His Leu Lys Arg Thr Ile Pro Gly Ala Glu Asn Gln 
            180                 185                 190         


Pro Val Ile Ala Ile Gly Gly Ser Tyr Gly Gly Met Leu Ala Ala Trp 
        195                 200                 205             


Phe Arg Met Lys Tyr Pro His Met Val Val Gly Ala Leu Ala Ala Ser 
    210                 215                 220                 


Ala Pro Ile Trp Gln Phe Glu Asp Leu Val Pro Cys Gly Val Phe Met 
225                 230                 235                 240 


Lys Ile Val Thr Thr Asp Phe Arg Lys Ser Gly Pro His Cys Ser Glu 
                245                 250                 255     


Ser Ile His Arg Ser Trp Asp Ala Ile Asn Arg Leu Ser Asn Thr Gly 
            260                 265                 270         


Ser Gly Leu Gln Trp Leu Thr Gly Ala Leu His Leu Cys Ser Pro Leu 
        275                 280                 285             


Thr Ser Gln Asp Ile Gln His Leu Lys Asp Trp Ile Ser Glu Thr Trp 
    290                 295                 300                 


Val Asn Leu Ala Met Val Asp Tyr Pro Tyr Ala Ser Asn Phe Leu Gln 
305                 310                 315                 320 


Pro Leu Pro Ala Trp Pro Ile Lys Val Val Cys Gln Tyr Leu Lys Asn 
                325                 330                 335     


Pro Asn Val Ser Asp Ser Leu Leu Leu Gln Asn Ile Phe Gln Ala Leu 
            340                 345                 350         


Asn Val Tyr Tyr Asn Tyr Ser Gly Gln Val Lys Cys Leu Asn Ile Ser 
        355                 360                 365             


Glu Thr Ala Thr Ser Ser Leu Gly Thr Leu Gly Trp Ser Tyr Gln Ala 
    370                 375                 380                 


Cys Thr Glu Val Val Met Pro Phe Cys Thr Asn Gly Val Asp Asp Met 
385                 390                 395                 400 


Phe Glu Pro His Ser Trp Asn Leu Lys Glu Leu Ser Asp Asp Cys Phe 
                405                 410                 415     


Gln Gln Trp Gly Val Arg Pro Arg Pro Ser Trp Ile Thr Thr Met Tyr 
            420                 425                 430         


Gly Gly Lys Asn Ile Ser Ser His Thr Asn Ile Val Phe Ser Asn Gly 
        435                 440                 445             


Glu Leu Asp Pro Trp Ser Gly Gly Gly Val Thr Lys Asp Ile Thr Asp 
    450                 455                 460                 


Thr Leu Val Ala Val Thr Ile Ser Glu Gly Ala His His Leu Asp Leu 
465                 470                 475                 480 


Arg Thr Lys Asn Ala Leu Asp Pro Met Ser Val Leu Leu Ala Arg Ser 
                485                 490                 495     


Leu Glu Val Arg His Met Lys Asn Trp Ile Arg Asp Phe Tyr Asp Ser 
            500                 505                 510         


Ala Gly Lys Gln His 
        515         


<210>  4328
<211>  640
<212>  PRT
<213>  homo sapiens

<400>  4328

Met Ala Leu Ser Arg Gly Leu Pro Arg Glu Leu Ala Glu Ala Val Ala 
1               5                   10                  15      


Gly Gly Arg Val Leu Val Val Gly Ala Gly Gly Ile Gly Cys Glu Leu 
            20                  25                  30          


Leu Lys Asn Leu Val Leu Thr Gly Phe Ser His Ile Asp Leu Ile Asp 
        35                  40                  45              


Leu Asp Thr Ile Asp Val Ser Asn Leu Asn Arg Gln Phe Leu Phe Gln 
    50                  55                  60                  


Lys Lys His Val Gly Arg Ser Lys Ala Gln Val Ala Lys Glu Ser Val 
65                  70                  75                  80  


Leu Gln Phe Tyr Pro Lys Ala Asn Ile Val Ala Tyr His Asp Ser Ile 
                85                  90                  95      


Met Asn Pro Asp Tyr Asn Val Glu Phe Phe Arg Gln Phe Ile Leu Val 
            100                 105                 110         


Met Asn Ala Leu Asp Asn Arg Ala Ala Arg Asn His Val Asn Arg Met 
        115                 120                 125             


Cys Leu Ala Ala Asp Val Pro Leu Ile Glu Ser Gly Thr Ala Gly Tyr 
    130                 135                 140                 


Leu Gly Gln Val Thr Thr Ile Lys Lys Gly Val Thr Glu Cys Tyr Glu 
145                 150                 155                 160 


Cys His Pro Lys Pro Thr Gln Arg Thr Phe Pro Gly Cys Thr Ile Arg 
                165                 170                 175     


Asn Thr Pro Ser Glu Pro Ile His Cys Ile Val Trp Ala Lys Tyr Leu 
            180                 185                 190         


Phe Asn Gln Leu Phe Gly Glu Glu Asp Ala Asp Gln Glu Val Ser Pro 
        195                 200                 205             


Asp Arg Ala Asp Pro Glu Ala Ala Trp Glu Pro Thr Glu Ala Glu Ala 
    210                 215                 220                 


Arg Ala Arg Ala Ser Asn Glu Asp Gly Asp Ile Lys Arg Ile Ser Thr 
225                 230                 235                 240 


Lys Glu Trp Ala Lys Ser Thr Gly Tyr Asp Pro Val Lys Leu Phe Thr 
                245                 250                 255     


Lys Leu Phe Lys Asp Asp Ile Arg Tyr Leu Leu Thr Met Asp Lys Leu 
            260                 265                 270         


Trp Arg Lys Arg Lys Pro Pro Val Pro Leu Asp Trp Ala Glu Val Gln 
        275                 280                 285             


Ser Gln Gly Glu Glu Thr Asn Ala Ser Asp Gln Gln Asn Glu Pro Gln 
    290                 295                 300                 


Leu Gly Leu Lys Asp Gln Gln Val Leu Asp Val Lys Ser Tyr Ala Arg 
305                 310                 315                 320 


Leu Phe Ser Lys Ser Ile Glu Thr Leu Arg Val His Leu Ala Glu Lys 
                325                 330                 335     


Gly Asp Gly Ala Glu Leu Ile Trp Asp Lys Asp Asp Pro Ser Ala Met 
            340                 345                 350         


Asp Phe Val Thr Ser Ala Ala Asn Leu Arg Met His Ile Phe Ser Met 
        355                 360                 365             


Asn Met Lys Ser Arg Phe Asp Ile Lys Ser Met Ala Gly Asn Ile Ile 
    370                 375                 380                 


Pro Ala Ile Ala Thr Thr Asn Ala Val Ile Ala Gly Leu Ile Val Leu 
385                 390                 395                 400 


Glu Gly Leu Lys Ile Leu Ser Gly Lys Ile Asp Gln Cys Arg Thr Ile 
                405                 410                 415     


Phe Leu Asn Lys Gln Pro Asn Pro Arg Lys Lys Leu Leu Val Pro Cys 
            420                 425                 430         


Ala Leu Asp Pro Pro Asn Pro Asn Cys Tyr Val Cys Ala Ser Lys Pro 
        435                 440                 445             


Glu Val Thr Val Arg Leu Asn Val His Lys Val Thr Val Leu Thr Leu 
    450                 455                 460                 


Gln Asp Lys Ile Val Lys Glu Lys Phe Ala Met Val Ala Pro Asp Val 
465                 470                 475                 480 


Gln Ile Glu Asp Gly Lys Gly Thr Ile Leu Ile Ser Ser Glu Glu Gly 
                485                 490                 495     


Glu Thr Glu Ala Asn Asn His Lys Lys Leu Ser Glu Phe Gly Ile Arg 
            500                 505                 510         


Asn Gly Ser Arg Leu Gln Ala Asp Asp Phe Leu Gln Asp Tyr Thr Leu 
        515                 520                 525             


Leu Ile Asn Ile Leu His Ser Glu Asp Leu Gly Lys Asp Val Glu Phe 
    530                 535                 540                 


Glu Val Val Gly Asp Ala Pro Glu Lys Val Gly Pro Lys Gln Ala Glu 
545                 550                 555                 560 


Asp Ala Ala Lys Ser Ile Thr Asn Gly Ser Asp Asp Gly Ala Gln Pro 
                565                 570                 575     


Ser Thr Ser Thr Ala Gln Glu Gln Asp Asp Val Leu Ile Val Asp Ser 
            580                 585                 590         


Asp Glu Glu Asp Ser Ser Asn Asn Ala Asp Val Ser Glu Glu Glu Arg 
        595                 600                 605             


Ser Arg Lys Arg Lys Leu Asp Glu Lys Glu Asn Leu Ser Ala Lys Arg 
    610                 615                 620                 


Ser Arg Ile Glu Gln Lys Glu Glu Leu Asp Asp Val Ile Ala Leu Asp 
625                 630                 635                 640 


<210>  4329
<211>  545
<212>  PRT
<213>  homo sapiens

<400>  4329

Met Ser Asn Asn Gly Leu Asp Ile Gln Asp Lys Pro Pro Ala Pro Pro 
1               5                   10                  15      


Met Arg Asn Thr Ser Thr Met Ile Gly Ala Gly Ser Lys Asp Ala Gly 
            20                  25                  30          


Thr Leu Asn His Gly Ser Lys Pro Leu Pro Pro Asn Pro Glu Glu Lys 
        35                  40                  45              


Lys Lys Lys Asp Arg Phe Tyr Arg Ser Ile Leu Pro Gly Asp Lys Thr 
    50                  55                  60                  


Asn Lys Lys Lys Glu Lys Glu Arg Pro Glu Ile Ser Leu Pro Ser Asp 
65                  70                  75                  80  


Phe Glu His Thr Ile His Val Gly Phe Asp Ala Val Thr Gly Glu Phe 
                85                  90                  95      


Thr Gly Met Pro Glu Gln Trp Ala Arg Leu Leu Gln Thr Ser Asn Ile 
            100                 105                 110         


Thr Lys Ser Glu Gln Lys Lys Asn Pro Gln Ala Val Leu Asp Val Leu 
        115                 120                 125             


Glu Phe Tyr Asn Ser Lys Lys Thr Ser Asn Ser Gln Lys Tyr Met Ser 
    130                 135                 140                 


Phe Thr Asp Lys Ser Ala Glu Asp Tyr Asn Ser Ser Asn Ala Leu Asn 
145                 150                 155                 160 


Val Lys Ala Val Ser Glu Thr Pro Ala Val Pro Pro Val Ser Glu Asp 
                165                 170                 175     


Glu Asp Asp Asp Asp Asp Asp Ala Thr Pro Pro Pro Val Ile Ala Pro 
            180                 185                 190         


Arg Pro Glu His Thr Lys Ser Val Tyr Thr Arg Ser Val Ile Glu Pro 
        195                 200                 205             


Leu Pro Val Thr Pro Thr Arg Asp Val Ala Thr Ser Pro Ile Ser Pro 
    210                 215                 220                 


Thr Glu Asn Asn Thr Thr Pro Pro Asp Ala Leu Thr Arg Asn Thr Glu 
225                 230                 235                 240 


Lys Gln Lys Lys Lys Pro Lys Met Ser Asp Glu Glu Ile Leu Glu Lys 
                245                 250                 255     


Leu Arg Ser Ile Val Ser Val Gly Asp Pro Lys Lys Lys Tyr Thr Arg 
            260                 265                 270         


Phe Glu Lys Ile Gly Gln Gly Ala Ser Gly Thr Val Tyr Thr Ala Met 
        275                 280                 285             


Asp Val Ala Thr Gly Gln Glu Val Ala Ile Lys Gln Met Asn Leu Gln 
    290                 295                 300                 


Gln Gln Pro Lys Lys Glu Leu Ile Ile Asn Glu Ile Leu Val Met Arg 
305                 310                 315                 320 


Glu Asn Lys Asn Pro Asn Ile Val Asn Tyr Leu Asp Ser Tyr Leu Val 
                325                 330                 335     


Gly Asp Glu Leu Trp Val Val Met Glu Tyr Leu Ala Gly Gly Ser Leu 
            340                 345                 350         


Thr Asp Val Val Thr Glu Thr Cys Met Asp Glu Gly Gln Ile Ala Ala 
        355                 360                 365             


Val Cys Arg Glu Cys Leu Gln Ala Leu Glu Phe Leu His Ser Asn Gln 
    370                 375                 380                 


Val Ile His Arg Asp Ile Lys Ser Asp Asn Ile Leu Leu Gly Met Asp 
385                 390                 395                 400 


Gly Ser Val Lys Leu Thr Asp Phe Gly Phe Cys Ala Gln Ile Thr Pro 
                405                 410                 415     


Glu Gln Ser Lys Arg Ser Thr Met Val Gly Thr Pro Tyr Trp Met Ala 
            420                 425                 430         


Pro Glu Val Val Thr Arg Lys Ala Tyr Gly Pro Lys Val Asp Ile Trp 
        435                 440                 445             


Ser Leu Gly Ile Met Ala Ile Glu Met Ile Glu Gly Glu Pro Pro Tyr 
    450                 455                 460                 


Leu Asn Glu Asn Pro Leu Arg Ala Leu Tyr Leu Ile Ala Thr Asn Gly 
465                 470                 475                 480 


Thr Pro Glu Leu Gln Asn Pro Glu Lys Leu Ser Ala Ile Phe Arg Asp 
                485                 490                 495     


Phe Leu Asn Arg Cys Leu Glu Met Asp Val Glu Lys Arg Gly Ser Ala 
            500                 505                 510         


Lys Glu Leu Leu Gln His Gln Phe Leu Lys Ile Ala Lys Pro Leu Ser 
        515                 520                 525             


Ser Leu Thr Pro Leu Ile Ala Ala Ala Lys Glu Ala Thr Lys Asn Asn 
    530                 535                 540                 


His 
545 


<210>  4330
<211>  449
<212>  PRT
<213>  homo sapiens

<400>  4330

Met Gly Arg Val Gly Gly Met Ala Gln Pro Met Gly Arg Ala Gly Ala 
1               5                   10                  15      


Pro Lys Pro Met Gly Arg Ala Gly Ser Ala Arg Arg Gly Arg Phe Lys 
            20                  25                  30          


Gly Cys Trp Ser Glu Gly Ser Pro Val His Pro Val Pro Ala Val Leu 
        35                  40                  45              


Ser Trp Leu Leu Ala Leu Leu Arg Cys Ala Ser Thr Met Leu Ser Leu 
    50                  55                  60                  


Arg Val Pro Leu Ala Pro Ile Thr Asp Pro Gln Gln Leu Gln Leu Ser 
65                  70                  75                  80  


Pro Leu Lys Gly Leu Ser Leu Val Asp Lys Glu Asn Thr Pro Pro Ala 
                85                  90                  95      


Leu Ser Gly Thr Arg Val Leu Ala Ser Lys Thr Ala Arg Arg Ile Phe 
            100                 105                 110         


Gln Glu Pro Thr Glu Pro Lys Thr Lys Ala Ala Ala Pro Gly Val Glu 
        115                 120                 125             


Asp Glu Pro Leu Leu Arg Glu Asn Pro Arg Arg Phe Val Ile Phe Pro 
    130                 135                 140                 


Ile Glu Tyr His Asp Ile Trp Gln Met Tyr Lys Lys Ala Glu Ala Ser 
145                 150                 155                 160 


Phe Trp Thr Ala Glu Glu Val Asp Leu Ser Lys Asp Ile Gln His Trp 
                165                 170                 175     


Glu Ser Leu Lys Pro Glu Glu Arg Tyr Phe Ile Ser His Val Leu Ala 
            180                 185                 190         


Phe Phe Ala Ala Ser Asp Gly Ile Val Asn Glu Asn Leu Val Glu Arg 
        195                 200                 205             


Phe Ser Gln Glu Val Gln Ile Thr Glu Ala Arg Cys Phe Tyr Gly Phe 
    210                 215                 220                 


Gln Ile Ala Met Glu Asn Ile His Ser Glu Met Tyr Ser Leu Leu Ile 
225                 230                 235                 240 


Asp Thr Tyr Ile Lys Asp Pro Lys Glu Arg Glu Phe Leu Phe Asn Ala 
                245                 250                 255     


Ile Glu Thr Met Pro Cys Val Lys Lys Lys Ala Asp Trp Ala Leu Arg 
            260                 265                 270         


Trp Ile Gly Asp Lys Glu Ala Thr Tyr Gly Glu Arg Val Val Ala Phe 
        275                 280                 285             


Ala Ala Val Glu Gly Ile Phe Phe Ser Gly Ser Phe Ala Ser Ile Phe 
    290                 295                 300                 


Trp Leu Lys Lys Arg Gly Leu Met Pro Gly Leu Thr Phe Ser Asn Glu 
305                 310                 315                 320 


Leu Ile Ser Arg Asp Glu Gly Leu His Cys Asp Phe Ala Cys Leu Met 
                325                 330                 335     


Phe Lys His Leu Val His Lys Pro Ser Glu Glu Arg Val Arg Glu Ile 
            340                 345                 350         


Ile Ile Asn Ala Val Arg Ile Glu Gln Glu Phe Leu Thr Glu Ala Leu 
        355                 360                 365             


Pro Val Lys Leu Ile Gly Met Asn Cys Thr Leu Met Lys Gln Tyr Ile 
    370                 375                 380                 


Glu Phe Val Ala Asp Arg Leu Met Leu Glu Leu Gly Phe Ser Lys Val 
385                 390                 395                 400 


Phe Arg Val Glu Asn Pro Phe Asp Phe Met Glu Asn Ile Ser Leu Glu 
                405                 410                 415     


Gly Lys Thr Asn Phe Phe Glu Lys Arg Val Gly Glu Tyr Gln Arg Met 
            420                 425                 430         


Gly Val Met Ser Ser Pro Thr Glu Asn Ser Phe Thr Leu Asp Ala Asp 
        435                 440                 445             


Phe 
    


<210>  4331
<211>  272
<212>  PRT
<213>  homo sapiens

<400>  4331

Met His Leu Arg Leu Ile Ser Trp Leu Phe Ile Ile Leu Asn Phe Met 
1               5                   10                  15      


Glu Tyr Ile Gly Ser Gln Asn Ala Ser Arg Gly Arg Arg Gln Arg Arg 
            20                  25                  30          


Met His Pro Asn Val Ser Gln Gly Cys Gln Gly Gly Cys Ala Thr Cys 
        35                  40                  45              


Ser Asp Tyr Asn Gly Cys Leu Ser Cys Lys Pro Arg Leu Phe Phe Ala 
    50                  55                  60                  


Leu Glu Arg Ile Gly Met Lys Gln Ile Gly Val Cys Leu Ser Ser Cys 
65                  70                  75                  80  


Pro Ser Gly Tyr Tyr Gly Thr Arg Tyr Pro Asp Ile Asn Lys Cys Thr 
                85                  90                  95      


Lys Cys Lys Ala Asp Cys Asp Thr Cys Phe Asn Lys Asn Phe Cys Thr 
            100                 105                 110         


Lys Cys Lys Ser Gly Phe Tyr Leu His Leu Gly Lys Cys Leu Asp Asn 
        115                 120                 125             


Cys Pro Glu Gly Leu Glu Ala Asn Asn His Thr Met Glu Cys Val Ser 
    130                 135                 140                 


Ile Val His Cys Glu Val Ser Glu Trp Asn Pro Trp Ser Pro Cys Thr 
145                 150                 155                 160 


Lys Lys Gly Lys Thr Cys Gly Phe Lys Arg Gly Thr Glu Thr Arg Val 
                165                 170                 175     


Arg Glu Ile Ile Gln His Pro Ser Ala Lys Gly Asn Leu Cys Pro Pro 
            180                 185                 190         


Thr Asn Glu Thr Arg Lys Cys Thr Val Gln Arg Lys Lys Cys Gln Lys 
        195                 200                 205             


Gly Glu Arg Gly Lys Lys Gly Arg Glu Arg Lys Arg Lys Lys Pro Asn 
    210                 215                 220                 


Lys Gly Glu Ser Lys Glu Ala Ile Pro Asp Ser Lys Ser Leu Glu Ser 
225                 230                 235                 240 


Ser Lys Glu Ile Pro Glu Gln Arg Glu Asn Lys Gln Gln Gln Lys Lys 
                245                 250                 255     


Arg Lys Val Gln Asp Lys Gln Lys Ser Val Ser Val Ser Thr Val His 
            260                 265                 270         


<210>  4332
<211>  348
<212>  PRT
<213>  homo sapiens

<400>  4332

Met Ser Leu Val Asp Leu Gly Lys Lys Leu Leu Glu Ala Ala Arg Ala 
1               5                   10                  15      


Gly Gln Asp Asp Glu Val Arg Ile Leu Met Ala Asn Gly Ala Pro Phe 
            20                  25                  30          


Thr Thr Asp Trp Leu Gly Thr Ser Pro Leu His Leu Ala Ala Gln Tyr 
        35                  40                  45              


Gly His Tyr Ser Thr Thr Glu Val Leu Leu Arg Ala Gly Val Ser Arg 
    50                  55                  60                  


Asp Ala Arg Thr Lys Val Asp Arg Thr Pro Leu His Met Ala Ala Ser 
65                  70                  75                  80  


Glu Gly His Ala Ser Ile Val Glu Val Leu Leu Lys His Gly Ala Asp 
                85                  90                  95      


Val Asn Ala Lys Asp Met Leu Lys Met Thr Ala Leu His Trp Ala Thr 
            100                 105                 110         


Glu His Asn His Gln Glu Val Val Glu Leu Leu Ile Lys Tyr Gly Ala 
        115                 120                 125             


Asp Val His Thr Gln Ser Lys Phe Cys Lys Thr Ala Phe Asp Ile Ser 
    130                 135                 140                 


Ile Asp Asn Gly Asn Glu Asp Leu Ala Glu Ile Leu Gln Ile Ala Met 
145                 150                 155                 160 


Gln Asn Gln Ile Asn Thr Asn Pro Glu Ser Pro Asp Thr Val Thr Ile 
                165                 170                 175     


His Ala Ala Thr Pro Gln Phe Ile Ile Gly Pro Gly Gly Val Val Asn 
            180                 185                 190         


Leu Thr Asp Glu Thr Gly Val Ser Ala Val Gln Phe Gly Asn Ser Ser 
        195                 200                 205             


Thr Ser Val Leu Ala Thr Leu Ala Ala Leu Ala Glu Ala Ser Ala Pro 
    210                 215                 220                 


Leu Ser Asn Ser Ser Glu Thr Pro Val Val Ala Thr Glu Glu Val Val 
225                 230                 235                 240 


Thr Ala Glu Ser Val Asp Gly Ala Ile Gln Gln Val Val Ser Ser Gly 
                245                 250                 255     


Gly Gln Gln Val Ile Thr Ile Val Thr Asp Gly Ile Gln Leu Gly Asn 
            260                 265                 270         


Leu His Ser Ile Pro Thr Ser Gly Ile Gly Gln Pro Ile Ile Val Thr 
        275                 280                 285             


Met Pro Asp Gly Gln Gln Val Leu Thr Val Pro Ala Thr Asp Ile Ala 
    290                 295                 300                 


Glu Glu Thr Val Ile Ser Glu Glu Pro Pro Ala Lys Arg Gln Cys Ile 
305                 310                 315                 320 


Glu Ile Ile Glu Asn Arg Val Glu Ser Ala Glu Ile Glu Val Arg Ser 
                325                 330                 335     


Leu Leu Pro Gly Val Leu Cys Arg Ser His Pro Lys 
            340                 345             


<210>  4333
<211>  473
<212>  PRT
<213>  homo sapiens

<400>  4333

Met Trp Gly Leu Ala Gly Gly Arg Leu Phe Gly Ile Phe Ser Ala Pro 
1               5                   10                  15      


Val Leu Val Ala Val Val Cys Cys Ala Gln Ser Val Asn Asp Pro Gly 
            20                  25                  30          


Asn Met Ser Phe Val Lys Glu Thr Val Asp Lys Leu Leu Lys Gly Tyr 
        35                  40                  45              


Asp Ile Arg Leu Arg Pro Asp Phe Gly Gly Pro Pro Val Cys Val Gly 
    50                  55                  60                  


Met Asn Ile Asp Ile Ala Ser Ile Asp Met Val Ser Glu Val Asn Met 
65                  70                  75                  80  


Asp Tyr Thr Leu Thr Met Tyr Phe Gln Gln Tyr Trp Arg Asp Lys Arg 
                85                  90                  95      


Leu Ala Tyr Ser Gly Ile Pro Leu Asn Leu Thr Leu Asp Asn Arg Val 
            100                 105                 110         


Ala Asp Gln Leu Trp Val Pro Asp Thr Tyr Phe Leu Asn Asp Lys Lys 
        115                 120                 125             


Ser Phe Val His Gly Val Thr Val Lys Asn Arg Met Ile Arg Leu His 
    130                 135                 140                 


Pro Asp Gly Thr Val Leu Tyr Gly Leu Arg Ile Thr Thr Thr Ala Ala 
145                 150                 155                 160 


Cys Met Met Asp Leu Arg Arg Tyr Pro Leu Asp Glu Gln Asn Cys Thr 
                165                 170                 175     


Leu Glu Ile Glu Ser Tyr Gly Tyr Thr Thr Asp Asp Ile Glu Phe Tyr 
            180                 185                 190         


Trp Arg Gly Gly Asp Lys Ala Val Thr Gly Val Glu Arg Ile Glu Leu 
        195                 200                 205             


Pro Gln Phe Ser Ile Val Glu His Arg Leu Val Ser Arg Asn Val Val 
    210                 215                 220                 


Phe Ala Thr Gly Ala Tyr Pro Arg Leu Ser Leu Ser Phe Arg Leu Lys 
225                 230                 235                 240 


Arg Asn Ile Gly Tyr Phe Ile Leu Gln Thr Tyr Met Pro Ser Ile Leu 
                245                 250                 255     


Ile Thr Ile Leu Ser Trp Val Ser Phe Trp Ile Asn Tyr Asp Ala Ser 
            260                 265                 270         


Ala Ala Arg Val Ala Leu Gly Ile Thr Thr Val Leu Thr Met Thr Thr 
        275                 280                 285             


Ile Asn Thr His Leu Arg Glu Thr Leu Pro Lys Ile Pro Tyr Val Lys 
    290                 295                 300                 


Ala Ile Asp Met Tyr Leu Met Gly Cys Phe Val Phe Val Phe Leu Ala 
305                 310                 315                 320 


Leu Leu Glu Tyr Ala Phe Val Asn Tyr Ile Phe Phe Gly Arg Gly Pro 
                325                 330                 335     


Gln Arg Gln Lys Lys Leu Ala Glu Lys Thr Ala Lys Ala Lys Asn Asp 
            340                 345                 350         


Arg Ser Lys Ser Glu Ser Asn Arg Val Asp Ala His Gly Asn Ile Leu 
        355                 360                 365             


Leu Thr Ser Leu Glu Val His Asn Glu Met Asn Glu Val Ser Gly Gly 
    370                 375                 380                 


Ile Gly Asp Thr Arg Asn Ser Ala Ile Ser Phe Asp Asn Ser Gly Ile 
385                 390                 395                 400 


Gln Tyr Arg Lys Gln Ser Met Pro Arg Glu Gly His Gly Arg Phe Leu 
                405                 410                 415     


Gly Asp Arg Ser Leu Pro His Lys Lys Thr His Leu Arg Arg Arg Ser 
            420                 425                 430         


Ser Gln Leu Lys Ile Lys Ile Pro Asp Leu Thr Asp Val Asn Ala Ile 
        435                 440                 445             


Asp Arg Trp Ser Arg Ile Val Phe Pro Phe Thr Phe Ser Leu Phe Asn 
    450                 455                 460                 


Leu Val Tyr Trp Leu Tyr Tyr Val Asn 
465                 470             


<210>  4334
<211>  602
<212>  PRT
<213>  homo sapiens

<400>  4334

Met His Ser Lys Val Thr Ile Ile Cys Ile Arg Phe Leu Phe Trp Phe 
1               5                   10                  15      


Leu Leu Leu Cys Met Leu Ile Gly Lys Ser His Thr Glu Asp Asp Ile 
            20                  25                  30          


Ile Ile Ala Thr Lys Asn Gly Lys Val Arg Gly Met Asn Leu Thr Val 
        35                  40                  45              


Phe Gly Gly Thr Val Thr Ala Phe Leu Gly Ile Pro Tyr Ala Gln Pro 
    50                  55                  60                  


Pro Leu Gly Arg Leu Arg Phe Lys Lys Pro Gln Ser Leu Thr Lys Trp 
65                  70                  75                  80  


Ser Asp Ile Trp Asn Ala Thr Lys Tyr Ala Asn Ser Cys Cys Gln Asn 
                85                  90                  95      


Ile Asp Gln Ser Phe Pro Gly Phe His Gly Ser Glu Met Trp Asn Pro 
            100                 105                 110         


Asn Thr Asp Leu Ser Glu Asp Cys Leu Tyr Leu Asn Val Trp Ile Pro 
        115                 120                 125             


Ala Pro Lys Pro Lys Asn Ala Thr Val Leu Ile Trp Ile Tyr Gly Gly 
    130                 135                 140                 


Gly Phe Gln Thr Gly Thr Ser Ser Leu His Val Tyr Asp Gly Lys Phe 
145                 150                 155                 160 


Leu Ala Arg Val Glu Arg Val Ile Val Val Ser Met Asn Tyr Arg Val 
                165                 170                 175     


Gly Ala Leu Gly Phe Leu Ala Leu Pro Gly Asn Pro Glu Ala Pro Gly 
            180                 185                 190         


Asn Met Gly Leu Phe Asp Gln Gln Leu Ala Leu Gln Trp Val Gln Lys 
        195                 200                 205             


Asn Ile Ala Ala Phe Gly Gly Asn Pro Lys Ser Val Thr Leu Phe Gly 
    210                 215                 220                 


Glu Ser Ala Gly Ala Ala Ser Val Ser Leu His Leu Leu Ser Pro Gly 
225                 230                 235                 240 


Ser His Ser Leu Phe Thr Arg Ala Ile Leu Gln Ser Gly Ser Phe Asn 
                245                 250                 255     


Ala Pro Trp Ala Val Thr Ser Leu Tyr Glu Ala Arg Asn Arg Thr Leu 
            260                 265                 270         


Asn Leu Ala Lys Leu Thr Gly Cys Ser Arg Glu Asn Glu Thr Glu Ile 
        275                 280                 285             


Ile Lys Cys Leu Arg Asn Lys Asp Pro Gln Glu Ile Leu Leu Asn Glu 
    290                 295                 300                 


Ala Phe Val Val Pro Tyr Gly Thr Pro Leu Ser Val Asn Phe Gly Pro 
305                 310                 315                 320 


Thr Val Asp Gly Asp Phe Leu Thr Asp Met Pro Asp Ile Leu Leu Glu 
                325                 330                 335     


Leu Gly Gln Phe Lys Lys Thr Gln Ile Leu Val Gly Val Asn Lys Asp 
            340                 345                 350         


Glu Gly Thr Ala Phe Leu Val Tyr Gly Ala Pro Gly Phe Ser Lys Asp 
        355                 360                 365             


Asn Asn Ser Ile Ile Thr Arg Lys Glu Phe Gln Glu Gly Leu Lys Ile 
    370                 375                 380                 


Phe Phe Pro Gly Val Ser Glu Phe Gly Lys Glu Ser Ile Leu Phe His 
385                 390                 395                 400 


Tyr Thr Asp Trp Val Asp Asp Gln Arg Pro Glu Asn Tyr Arg Glu Ala 
                405                 410                 415     


Leu Gly Asp Val Val Gly Asp Tyr Asn Phe Ile Cys Pro Ala Leu Glu 
            420                 425                 430         


Phe Thr Lys Lys Phe Ser Glu Trp Gly Asn Asn Ala Phe Phe Tyr Tyr 
        435                 440                 445             


Phe Glu His Arg Ser Ser Lys Leu Pro Trp Pro Glu Trp Met Gly Val 
    450                 455                 460                 


Met His Gly Tyr Glu Ile Glu Phe Val Phe Gly Leu Pro Leu Glu Arg 
465                 470                 475                 480 


Arg Asp Asn Tyr Thr Lys Ala Glu Glu Ile Leu Ser Arg Ser Ile Val 
                485                 490                 495     


Lys Arg Trp Ala Asn Phe Ala Lys Tyr Gly Asn Pro Asn Glu Thr Gln 
            500                 505                 510         


Asn Asn Ser Thr Ser Trp Pro Val Phe Lys Ser Thr Glu Gln Lys Tyr 
        515                 520                 525             


Leu Thr Leu Asn Thr Glu Ser Thr Arg Ile Met Thr Lys Leu Arg Ala 
    530                 535                 540                 


Gln Gln Cys Arg Phe Trp Thr Ser Phe Phe Pro Lys Val Leu Glu Met 
545                 550                 555                 560 


Thr Gly Asn Ile Asp Glu Ala Glu Trp Glu Trp Lys Ala Gly Phe His 
                565                 570                 575     


Arg Trp Asn Asn Tyr Met Met Asp Trp Lys Asn Gln Phe Asn Asp Tyr 
            580                 585                 590         


Thr Ser Lys Lys Glu Ser Cys Val Gly Leu 
        595                 600         


<210>  4335
<211>  473
<212>  PRT
<213>  homo sapiens

<400>  4335

Met Cys Ser Gly Leu Leu Glu Leu Leu Leu Pro Ile Trp Leu Ser Trp 
1               5                   10                  15      


Thr Leu Gly Thr Arg Gly Ser Glu Pro Arg Ser Val Asn Asp Pro Gly 
            20                  25                  30          


Asn Met Ser Phe Val Lys Glu Thr Val Asp Lys Leu Leu Lys Gly Tyr 
        35                  40                  45              


Asp Ile Arg Leu Arg Pro Asp Phe Gly Gly Pro Pro Val Cys Val Gly 
    50                  55                  60                  


Met Asn Ile Asp Ile Ala Ser Ile Asp Met Val Ser Glu Val Asn Met 
65                  70                  75                  80  


Asp Tyr Thr Leu Thr Met Tyr Phe Gln Gln Tyr Trp Arg Asp Lys Arg 
                85                  90                  95      


Leu Ala Tyr Ser Gly Ile Pro Leu Asn Leu Thr Leu Asp Asn Arg Val 
            100                 105                 110         


Ala Asp Gln Leu Trp Val Pro Asp Thr Tyr Phe Leu Asn Asp Lys Lys 
        115                 120                 125             


Ser Phe Val His Gly Val Thr Val Lys Asn Arg Met Ile Arg Leu His 
    130                 135                 140                 


Pro Asp Gly Thr Val Leu Tyr Gly Leu Arg Ile Thr Thr Thr Ala Ala 
145                 150                 155                 160 


Cys Met Met Asp Leu Arg Arg Tyr Pro Leu Asp Glu Gln Asn Cys Thr 
                165                 170                 175     


Leu Glu Ile Glu Ser Tyr Gly Tyr Thr Thr Asp Asp Ile Glu Phe Tyr 
            180                 185                 190         


Trp Arg Gly Gly Asp Lys Ala Val Thr Gly Val Glu Arg Ile Glu Leu 
        195                 200                 205             


Pro Gln Phe Ser Ile Val Glu His Arg Leu Val Ser Arg Asn Val Val 
    210                 215                 220                 


Phe Ala Thr Gly Ala Tyr Pro Arg Leu Ser Leu Ser Phe Arg Leu Lys 
225                 230                 235                 240 


Arg Asn Ile Gly Tyr Phe Ile Leu Gln Thr Tyr Met Pro Ser Ile Leu 
                245                 250                 255     


Ile Thr Ile Leu Ser Trp Val Ser Phe Trp Ile Asn Tyr Asp Ala Ser 
            260                 265                 270         


Ala Ala Arg Val Ala Leu Gly Ile Thr Thr Val Leu Thr Met Thr Thr 
        275                 280                 285             


Ile Asn Thr His Leu Arg Glu Thr Leu Pro Lys Ile Pro Tyr Val Lys 
    290                 295                 300                 


Ala Ile Asp Met Tyr Leu Met Gly Cys Phe Val Phe Val Phe Leu Ala 
305                 310                 315                 320 


Leu Leu Glu Tyr Ala Phe Val Asn Tyr Ile Phe Phe Gly Arg Gly Pro 
                325                 330                 335     


Gln Arg Gln Lys Lys Leu Ala Glu Lys Thr Ala Lys Ala Lys Asn Asp 
            340                 345                 350         


Arg Ser Lys Ser Glu Ser Asn Arg Val Asp Ala His Gly Asn Ile Leu 
        355                 360                 365             


Leu Thr Ser Leu Glu Val His Asn Glu Met Asn Glu Val Ser Gly Gly 
    370                 375                 380                 


Ile Gly Asp Thr Arg Asn Ser Ala Ile Ser Phe Asp Asn Ser Gly Ile 
385                 390                 395                 400 


Gln Tyr Arg Lys Gln Ser Met Pro Arg Glu Gly His Gly Arg Phe Leu 
                405                 410                 415     


Gly Asp Arg Ser Leu Pro His Lys Lys Thr His Leu Arg Arg Arg Ser 
            420                 425                 430         


Ser Gln Leu Lys Ile Lys Ile Pro Asp Leu Thr Asp Val Asn Ala Ile 
        435                 440                 445             


Asp Arg Trp Ser Arg Ile Val Phe Pro Phe Thr Phe Ser Leu Phe Asn 
    450                 455                 460                 


Leu Val Tyr Trp Leu Tyr Tyr Val Asn 
465                 470             


<210>  4336
<211>  376
<212>  PRT
<213>  homo sapiens

<400>  4336

Met Val Val Val Ala Ala Ala Pro Asn Pro Ala Asp Gly Thr Pro Lys 
1               5                   10                  15      


Val Leu Leu Leu Ser Gly Gln Pro Ala Ser Ala Ala Gly Ala Pro Ala 
            20                  25                  30          


Gly Gln Ala Leu Pro Leu Met Val Pro Ala Gln Arg Gly Ala Ser Pro 
        35                  40                  45              


Glu Ala Ala Ser Gly Gly Leu Pro Gln Ala Arg Lys Arg Gln Arg Leu 
    50                  55                  60                  


Thr His Leu Ser Pro Glu Glu Lys Ala Leu Arg Arg Lys Leu Lys Asn 
65                  70                  75                  80  


Arg Val Ala Ala Gln Thr Ala Arg Asp Arg Lys Lys Ala Arg Met Ser 
                85                  90                  95      


Glu Leu Glu Gln Gln Val Val Asp Leu Glu Glu Glu Asn Gln Lys Leu 
            100                 105                 110         


Leu Leu Glu Asn Gln Leu Leu Arg Glu Lys Thr His Gly Leu Val Val 
        115                 120                 125             


Glu Asn Gln Glu Leu Arg Gln Arg Leu Gly Met Asp Ala Leu Val Ala 
    130                 135                 140                 


Glu Glu Glu Ala Glu Ala Lys Gly Asn Glu Val Arg Pro Val Ala Gly 
145                 150                 155                 160 


Ser Ala Glu Ser Ala Ala Gly Ala Gly Pro Val Val Thr Pro Pro Glu 
                165                 170                 175     


His Leu Pro Met Asp Ser Gly Gly Ile Asp Ser Ser Asp Ser Glu Ser 
            180                 185                 190         


Asp Ile Leu Leu Gly Ile Leu Asp Asn Leu Asp Pro Val Met Phe Phe 
        195                 200                 205             


Lys Cys Pro Ser Pro Glu Pro Ala Ser Leu Glu Glu Leu Pro Glu Val 
    210                 215                 220                 


Tyr Pro Glu Gly Pro Ser Ser Leu Pro Ala Ser Leu Ser Leu Ser Val 
225                 230                 235                 240 


Gly Thr Ser Ser Ala Lys Leu Glu Ala Ile Asn Glu Leu Ile Arg Phe 
                245                 250                 255     


Asp His Ile Tyr Thr Lys Pro Leu Val Leu Glu Ile Pro Ser Glu Thr 
            260                 265                 270         


Glu Ser Gln Ala Asn Val Val Val Lys Ile Glu Glu Ala Pro Leu Ser 
        275                 280                 285             


Pro Ser Glu Asn Asp His Pro Glu Phe Ile Val Ser Val Lys Glu Glu 
    290                 295                 300                 


Pro Val Glu Asp Asp Leu Val Pro Glu Leu Gly Ile Ser Asn Leu Leu 
305                 310                 315                 320 


Ser Ser Ser His Cys Pro Lys Pro Ser Ser Cys Leu Leu Asp Ala Tyr 
                325                 330                 335     


Ser Asp Cys Gly Tyr Gly Gly Ser Leu Ser Pro Phe Ser Asp Met Ser 
            340                 345                 350         


Ser Leu Leu Gly Val Asn His Ser Trp Glu Asp Thr Phe Ala Asn Glu 
        355                 360                 365             


Leu Phe Pro Gln Leu Ile Ser Val 
    370                 375     


<210>  4337
<211>  959
<212>  PRT
<213>  homo sapiens

<400>  4337

Met Val Ala Ala Pro Cys Ala Arg Arg Leu Ala Arg Arg Ser His Ser 
1               5                   10                  15      


Ala Leu Leu Ala Ala Leu Thr Val Leu Leu Leu Gln Thr Leu Val Val 
            20                  25                  30          


Trp Asn Phe Ser Ser Leu Asp Ser Gly Ala Gly Glu Arg Arg Gly Gly 
        35                  40                  45              


Ala Ala Val Gly Gly Gly Glu Gln Pro Pro Pro Ala Pro Ala Pro Arg 
    50                  55                  60                  


Arg Glu Arg Arg Asp Leu Pro Ala Glu Pro Ala Ala Ala Arg Gly Gly 
65                  70                  75                  80  


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Arg Gly Pro Gln Ala Arg 
                85                  90                  95      


Ala Arg Gly Gly Gly Pro Gly Glu Pro Arg Gly Gln Gln Pro Ala Ser 
            100                 105                 110         


Arg Gly Ala Leu Pro Ala Arg Ala Leu Asp Pro His Pro Ser Pro Leu 
        115                 120                 125             


Ile Thr Leu Glu Thr Gln Asp Gly Tyr Phe Ser His Arg Pro Lys Glu 
    130                 135                 140                 


Lys Val Arg Thr Asp Ser Asn Asn Glu Asn Ser Val Pro Lys Asp Phe 
145                 150                 155                 160 


Glu Asn Val Asp Asn Ser Asn Phe Ala Pro Arg Thr Gln Lys Gln Lys 
                165                 170                 175     


His Gln Pro Glu Leu Ala Lys Lys Pro Pro Ser Arg Gln Lys Glu Leu 
            180                 185                 190         


Leu Lys Arg Lys Leu Glu Gln Gln Glu Lys Gly Lys Gly His Thr Phe 
        195                 200                 205             


Pro Gly Lys Gly Pro Gly Glu Val Leu Pro Pro Gly Asp Arg Ala Ala 
    210                 215                 220                 


Ala Asn Ser Ser His Gly Lys Asp Val Ser Arg Pro Pro His Ala Arg 
225                 230                 235                 240 


Lys Thr Gly Gly Ser Ser Pro Glu Thr Lys Tyr Asp Gln Pro Pro Lys 
                245                 250                 255     


Cys Asp Ile Ser Gly Lys Glu Ala Ile Ser Ala Leu Ser Arg Ala Lys 
            260                 265                 270         


Ser Lys His Cys Arg Gln Glu Ile Gly Glu Thr Tyr Cys Arg His Lys 
        275                 280                 285             


Leu Gly Leu Leu Met Pro Glu Lys Val Thr Arg Phe Cys Pro Leu Glu 
    290                 295                 300                 


Gly Lys Ala Asn Lys Asn Val Gln Trp Asp Glu Asp Ser Val Glu Tyr 
305                 310                 315                 320 


Met Pro Ala Asn Pro Val Arg Ile Ala Phe Val Leu Val Val His Gly 
                325                 330                 335     


Arg Ala Ser Arg Gln Leu Gln Arg Met Phe Lys Ala Ile Tyr His Lys 
            340                 345                 350         


Asp His Phe Tyr Tyr Ile His Val Asp Lys Arg Ser Asn Tyr Leu His 
        355                 360                 365             


Arg Gln Val Leu Gln Val Ser Arg Gln Tyr Ser Asn Val Arg Val Thr 
    370                 375                 380                 


Pro Trp Arg Met Ala Thr Ile Trp Gly Gly Ala Ser Leu Leu Ser Thr 
385                 390                 395                 400 


Tyr Leu Gln Ser Met Arg Asp Leu Leu Glu Met Thr Asp Trp Pro Trp 
                405                 410                 415     


Asp Phe Phe Ile Asn Leu Ser Ala Ala Asp Tyr Pro Ile Arg Thr Asn 
            420                 425                 430         


Asp Gln Leu Val Ala Phe Leu Ser Arg Tyr Arg Asp Met Asn Phe Leu 
        435                 440                 445             


Lys Ser His Gly Arg Asp Asn Ala Arg Phe Ile Arg Lys Gln Gly Leu 
    450                 455                 460                 


Asp Arg Leu Phe Leu Glu Cys Asp Ala His Met Trp Arg Leu Gly Asp 
465                 470                 475                 480 


Arg Arg Ile Pro Glu Gly Ile Ala Val Asp Gly Gly Ser Asp Trp Phe 
                485                 490                 495     


Leu Leu Asn Arg Arg Phe Val Glu Tyr Val Thr Phe Ser Thr Asp Asp 
            500                 505                 510         


Leu Val Thr Lys Met Lys Gln Phe Tyr Ser Tyr Thr Leu Leu Pro Ala 
        515                 520                 525             


Glu Ser Phe Phe His Thr Val Leu Glu Asn Ser Pro His Cys Asp Thr 
    530                 535                 540                 


Met Val Asp Asn Asn Leu Arg Ile Thr Asn Trp Asn Arg Lys Leu Gly 
545                 550                 555                 560 


Cys Lys Cys Gln Tyr Lys His Ile Val Asp Trp Cys Gly Cys Ser Pro 
                565                 570                 575     


Asn Asp Phe Lys Pro Gln Asp Phe His Arg Phe Gln Gln Thr Ala Arg 
            580                 585                 590         


Pro Thr Phe Phe Ala Arg Lys Phe Glu Ala Val Val Asn Gln Glu Ile 
        595                 600                 605             


Ile Gly Gln Leu Asp Tyr Tyr Leu Tyr Gly Asn Tyr Pro Ala Gly Thr 
    610                 615                 620                 


Pro Gly Leu Arg Ser Tyr Trp Glu Asn Val Tyr Asp Glu Pro Asp Gly 
625                 630                 635                 640 


Ile His Ser Leu Ser Asp Val Thr Leu Thr Leu Tyr His Ser Phe Ala 
                645                 650                 655     


Arg Leu Gly Leu Arg Arg Ala Glu Thr Ser Leu His Thr Asp Gly Glu 
            660                 665                 670         


Asn Ser Cys Arg Tyr Tyr Pro Met Gly His Pro Ala Ser Val His Leu 
        675                 680                 685             


Tyr Phe Leu Ala Asp Arg Phe Gln Gly Phe Leu Ile Lys His His Ala 
    690                 695                 700                 


Thr Asn Leu Ala Val Ser Lys Leu Glu Thr Leu Glu Thr Trp Val Met 
705                 710                 715                 720 


Pro Lys Lys Val Phe Lys Ile Ala Ser Pro Pro Ser Asp Phe Gly Arg 
                725                 730                 735     


Leu Gln Phe Ser Glu Val Gly Thr Asp Trp Asp Ala Lys Glu Arg Leu 
            740                 745                 750         


Phe Arg Asn Phe Gly Gly Leu Leu Gly Pro Met Asp Glu Pro Val Gly 
        755                 760                 765             


Met Gln Lys Trp Gly Lys Gly Pro Asn Val Thr Val Thr Val Ile Trp 
    770                 775                 780                 


Val Asp Pro Val Asn Val Ile Ala Ala Thr Tyr Asp Ile Leu Ile Glu 
785                 790                 795                 800 


Ser Thr Ala Glu Phe Thr His Tyr Lys Pro Pro Leu Asn Leu Pro Leu 
                805                 810                 815     


Arg Pro Gly Val Trp Thr Val Lys Ile Leu His His Trp Val Pro Val 
            820                 825                 830         


Ala Glu Thr Lys Phe Leu Val Ala Pro Leu Thr Phe Ser Asn Arg Gln 
        835                 840                 845             


Pro Ile Lys Pro Glu Glu Ala Leu Lys Leu His Asn Gly Pro Leu Arg 
    850                 855                 860                 


Asn Ala Tyr Met Glu Gln Ser Phe Gln Ser Leu Asn Pro Val Leu Ser 
865                 870                 875                 880 


Leu Pro Ile Asn Pro Ala Gln Val Glu Gln Ala Arg Arg Asn Ala Ala 
                885                 890                 895     


Ser Thr Gly Thr Ala Leu Glu Gly Trp Leu Asp Ser Leu Val Gly Gly 
            900                 905                 910         


Met Trp Thr Ala Met Asp Ile Cys Ala Thr Gly Pro Thr Ala Cys Pro 
        915                 920                 925             


Val Met Gln Thr Cys Ser Gln Thr Ala Trp Ser Ser Phe Ser Pro Asp 
    930                 935                 940                 


Pro Lys Ser Glu Leu Gly Ala Val Lys Pro Asp Gly Arg Leu Arg 
945                 950                 955                 


<210>  4338
<211>  514
<212>  PRT
<213>  homo sapiens

<400>  4338

Met Val Glu Glu Val Gln Lys His Ser Val His Thr Leu Val Phe Arg 
1               5                   10                  15      


Ser Leu Lys Arg Thr His Asp Met Phe Val Ala Asp Asn Gly Lys Pro 
            20                  25                  30          


Val Pro Leu Asp Glu Glu Ser His Lys Arg Lys Met Ala Ile Lys Leu 
        35                  40                  45              


Arg Asn Glu Tyr Gly Pro Val Leu His Met Pro Thr Ser Lys Glu Asn 
    50                  55                  60                  


Leu Lys Glu Lys Gly Pro Gln Asn Ala Thr Asp Ser Tyr Val His Lys 
65                  70                  75                  80  


Gln Tyr Pro Ala Asn Gln Gly Gln Glu Val Glu Tyr Phe Val Ala Gly 
                85                  90                  95      


Thr His Pro Tyr Pro Pro Gly Pro Gly Val Ala Leu Thr Ala Asp Thr 
            100                 105                 110         


Lys Ile Gln Arg Met Pro Ser Glu Ser Ala Ala Gln Ser Leu Ala Val 
        115                 120                 125             


Ala Leu Pro Leu Gln Thr Lys Ala Asp Ala Asn Arg Thr Ala Pro Ser 
    130                 135                 140                 


Gly Ser Glu Tyr Arg His Pro Gly Ala Ser Asp Arg Pro Gln Pro Thr 
145                 150                 155                 160 


Ala Met Asn Ser Ile Val Met Glu Thr Gly Asn Thr Lys Asn Ser Ala 
                165                 170                 175     


Leu Met Ala Lys Lys Ala Pro Thr Met Pro Lys Pro Gln Trp His Pro 
            180                 185                 190         


Pro Trp Lys Leu Tyr Arg Val Ile Ser Gly His Leu Gly Trp Val Arg 
        195                 200                 205             


Cys Ile Ala Val Glu Pro Gly Asn Gln Trp Phe Val Thr Gly Ser Ala 
    210                 215                 220                 


Asp Arg Thr Ile Lys Ile Trp Asp Leu Ala Ser Gly Lys Leu Lys Leu 
225                 230                 235                 240 


Ser Leu Thr Gly His Ile Ser Thr Val Arg Gly Val Ile Val Ser Thr 
                245                 250                 255     


Arg Ser Pro Tyr Leu Phe Ser Cys Gly Glu Asp Lys Gln Val Lys Cys 
            260                 265                 270         


Trp Asp Leu Glu Tyr Asn Lys Val Ile Arg His Tyr His Gly His Leu 
        275                 280                 285             


Ser Ala Val Tyr Gly Leu Asp Leu His Pro Thr Ile Asp Val Leu Val 
    290                 295                 300                 


Thr Cys Ser Arg Asp Ser Thr Ala Arg Ile Trp Asp Val Arg Thr Lys 
305                 310                 315                 320 


Ala Ser Val His Thr Leu Ser Gly His Thr Asn Ala Val Ala Thr Val 
                325                 330                 335     


Arg Cys Gln Ala Ala Glu Pro Gln Ile Ile Thr Gly Ser His Asp Thr 
            340                 345                 350         


Thr Ile Arg Leu Trp Asp Leu Val Ala Gly Lys Thr Arg Val Thr Leu 
        355                 360                 365             


Thr Asn His Lys Lys Ser Val Arg Ala Val Val Leu His Pro Arg His 
    370                 375                 380                 


Tyr Thr Phe Ala Ser Gly Ser Pro Asp Asn Ile Lys Gln Trp Lys Phe 
385                 390                 395                 400 


Pro Asp Gly Ser Phe Ile Gln Asn Leu Ser Gly His Asn Ala Ile Ile 
                405                 410                 415     


Asn Thr Leu Thr Val Asn Ser Asp Gly Val Leu Val Ser Gly Ala Asp 
            420                 425                 430         


Asn Gly Thr Met His Leu Trp Asp Trp Arg Thr Gly Tyr Asn Phe Gln 
        435                 440                 445             


Arg Val His Ala Ala Val Gln Pro Gly Ser Leu Asp Ser Glu Ser Gly 
    450                 455                 460                 


Ile Phe Ala Cys Ala Phe Asp Gln Ser Glu Ser Arg Leu Leu Thr Ala 
465                 470                 475                 480 


Glu Ala Asp Lys Thr Ile Lys Val Tyr Arg Glu Asp Asp Thr Ala Thr 
                485                 490                 495     


Glu Glu Thr His Pro Val Ser Trp Lys Pro Glu Ile Ile Lys Arg Lys 
            500                 505                 510         


Arg Phe 
        


<210>  4339
<211>  443
<212>  PRT
<213>  homo sapiens

<400>  4339

Met Ala Thr Ala Ala Ser Asn His Tyr Ser Leu Leu Thr Ser Ser Ala 
1               5                   10                  15      


Ser Ile Val His Ala Glu Pro Pro Gly Gly Met Gln Gln Gly Ala Gly 
            20                  25                  30          


Gly Tyr Arg Glu Ala Gln Ser Leu Val Gln Gly Asp Tyr Gly Ala Leu 
        35                  40                  45              


Gln Ser Asn Gly His Pro Leu Ser His Ala His Gln Trp Ile Thr Ala 
    50                  55                  60                  


Leu Ser His Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly 
65                  70                  75                  80  


Gly Gly Gly Gly Gly Gly Gly Gly Asp Gly Ser Pro Trp Ser Thr Ser 
                85                  90                  95      


Pro Leu Gly Gln Pro Asp Ile Lys Pro Ser Val Val Val Gln Gln Gly 
            100                 105                 110         


Gly Arg Gly Asp Glu Leu His Gly Pro Gly Ala Leu Gln Gln Gln His 
        115                 120                 125             


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln 
    130                 135                 140                 


Gln Gln Gln Gln Gln Arg Pro Pro His Leu Val His His Ala Ala Asn 
145                 150                 155                 160 


His His Pro Gly Pro Gly Ala Trp Arg Ser Ala Ala Ala Ala Ala His 
                165                 170                 175     


Leu Pro Pro Ser Met Gly Ala Ser Asn Gly Gly Leu Leu Tyr Ser Gln 
            180                 185                 190         


Pro Ser Phe Thr Val Asn Gly Met Leu Gly Ala Gly Gly Gln Pro Ala 
        195                 200                 205             


Gly Leu His His His Gly Leu Arg Asp Ala His Asp Glu Pro His His 
    210                 215                 220                 


Ala Asp His His Pro His Pro His Ser His Pro His Gln Gln Pro Pro 
225                 230                 235                 240 


Pro Pro Pro Pro Pro Gln Gly Pro Pro Gly His Pro Gly Ala His His 
                245                 250                 255     


Asp Pro His Ser Asp Glu Asp Thr Pro Thr Ser Asp Asp Leu Glu Gln 
            260                 265                 270         


Phe Ala Lys Gln Phe Lys Gln Arg Arg Ile Lys Leu Gly Phe Thr Gln 
        275                 280                 285             


Ala Asp Val Gly Leu Ala Leu Gly Thr Leu Tyr Gly Asn Val Phe Ser 
    290                 295                 300                 


Gln Thr Thr Ile Cys Arg Phe Glu Ala Leu Gln Leu Ser Phe Lys Asn 
305                 310                 315                 320 


Met Cys Lys Leu Lys Pro Leu Leu Asn Lys Trp Leu Glu Glu Ala Asp 
                325                 330                 335     


Ser Ser Ser Gly Ser Pro Thr Ser Ile Asp Lys Ile Ala Ala Gln Gly 
            340                 345                 350         


Arg Lys Arg Lys Lys Arg Thr Ser Ile Glu Val Ser Val Lys Gly Ala 
        355                 360                 365             


Leu Glu Ser His Phe Leu Lys Cys Pro Lys Pro Ser Ala Gln Glu Ile 
    370                 375                 380                 


Thr Ser Leu Ala Asp Ser Leu Gln Leu Glu Lys Glu Val Val Arg Val 
385                 390                 395                 400 


Trp Phe Cys Asn Arg Arg Gln Lys Glu Lys Arg Met Thr Pro Pro Gly 
                405                 410                 415     


Gly Thr Leu Pro Gly Ala Glu Asp Val Tyr Gly Gly Ser Arg Asp Thr 
            420                 425                 430         


Pro Pro His His Gly Val Gln Thr Pro Val Gln 
        435                 440             


<210>  4340
<211>  587
<212>  PRT
<213>  homo sapiens

<400>  4340

Met Ala Ser Glu Asp Ile Ala Lys Leu Ala Glu Thr Leu Ala Lys Thr 
1               5                   10                  15      


Gln Val Ala Gly Gly Gln Leu Ser Phe Lys Gly Lys Ser Leu Lys Leu 
            20                  25                  30          


Asn Thr Ala Glu Asp Ala Lys Asp Val Ile Lys Glu Ile Glu Asp Phe 
        35                  40                  45              


Asp Ser Leu Glu Ala Leu Arg Leu Glu Gly Asn Thr Val Gly Val Glu 
    50                  55                  60                  


Ala Ala Arg Val Ile Ala Lys Ala Leu Glu Lys Lys Ser Glu Leu Lys 
65                  70                  75                  80  


Arg Cys His Trp Ser Asp Met Phe Thr Gly Arg Leu Arg Thr Glu Ile 
                85                  90                  95      


Pro Pro Ala Leu Ile Ser Leu Gly Glu Gly Leu Ile Thr Ala Gly Ala 
            100                 105                 110         


Gln Leu Val Glu Leu Asp Leu Ser Asp Asn Ala Phe Gly Pro Asp Gly 
        115                 120                 125             


Val Gln Gly Phe Glu Ala Leu Leu Lys Ser Ser Ala Cys Phe Thr Leu 
    130                 135                 140                 


Gln Glu Leu Lys Leu Asn Asn Cys Gly Met Gly Ile Gly Gly Gly Lys 
145                 150                 155                 160 


Ile Leu Ala Ala Ala Leu Thr Glu Cys His Arg Lys Ser Ser Ala Gln 
                165                 170                 175     


Gly Lys Pro Leu Ala Leu Lys Val Phe Val Ala Gly Arg Asn Arg Leu 
            180                 185                 190         


Glu Asn Asp Gly Ala Thr Ala Leu Ala Glu Ala Phe Arg Val Ile Gly 
        195                 200                 205             


Thr Leu Glu Glu Val His Met Pro Gln Asn Gly Ile Asn His Pro Gly 
    210                 215                 220                 


Ile Thr Ala Leu Ala Gln Ala Phe Ala Val Asn Pro Leu Leu Arg Val 
225                 230                 235                 240 


Ile Asn Leu Asn Asp Asn Thr Phe Thr Glu Lys Gly Ala Val Ala Met 
                245                 250                 255     


Ala Glu Thr Leu Lys Thr Leu Arg Gln Val Glu Val Ile Asn Phe Gly 
            260                 265                 270         


Asp Cys Leu Val Arg Ser Lys Gly Ala Val Ala Ile Ala Asp Ala Ile 
        275                 280                 285             


Arg Gly Gly Leu Pro Lys Leu Lys Glu Leu Asn Leu Ser Phe Cys Glu 
    290                 295                 300                 


Ile Lys Arg Asp Ala Ala Leu Ala Val Ala Glu Ala Met Ala Asp Lys 
305                 310                 315                 320 


Ala Glu Leu Glu Lys Leu Asp Leu Asn Gly Asn Thr Leu Gly Glu Glu 
                325                 330                 335     


Gly Cys Glu Gln Leu Gln Glu Val Leu Glu Gly Phe Asn Met Ala Lys 
            340                 345                 350         


Val Leu Ala Ser Leu Ser Asp Asp Glu Asp Glu Glu Glu Glu Glu Glu 
        355                 360                 365             


Gly Glu Glu Glu Glu Glu Glu Ala Glu Glu Glu Glu Glu Glu Asp Glu 
    370                 375                 380                 


Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Pro Gln Gln 
385                 390                 395                 400 


Arg Gly Gln Gly Glu Lys Ser Ala Thr Pro Ser Arg Lys Ile Leu Asp 
                405                 410                 415     


Pro Asn Thr Gly Glu Pro Ala Pro Val Leu Ser Ser Pro Pro Pro Ala 
            420                 425                 430         


Asp Val Ser Thr Phe Leu Ala Phe Pro Ser Pro Glu Lys Leu Leu Arg 
        435                 440                 445             


Leu Gly Pro Lys Ser Ser Val Leu Ile Ala Gln Gln Thr Asp Thr Ser 
    450                 455                 460                 


Asp Pro Glu Lys Val Val Ser Ala Phe Leu Lys Val Ser Ser Val Phe 
465                 470                 475                 480 


Lys Asp Glu Ala Thr Val Arg Met Ala Val Gln Asp Ala Val Asp Ala 
                485                 490                 495     


Leu Met Gln Lys Ala Phe Asn Ser Ser Ser Phe Asn Ser Asn Thr Phe 
            500                 505                 510         


Leu Thr Arg Leu Leu Val His Met Gly Leu Leu Lys Ser Glu Asp Lys 
        515                 520                 525             


Val Lys Ala Ile Ala Asn Leu Tyr Gly Pro Leu Met Ala Leu Asn His 
    530                 535                 540                 


Met Val Gln Gln Asp Tyr Phe Pro Lys Ala Leu Ala Pro Leu Leu Leu 
545                 550                 555                 560 


Ala Phe Val Thr Lys Pro Asn Ser Ala Leu Glu Ser Cys Ser Phe Ala 
                565                 570                 575     


Arg His Ser Leu Leu Gln Thr Leu Tyr Lys Val 
            580                 585         


<210>  4341
<211>  305
<212>  PRT
<213>  homo sapiens

<400>  4341

Met Glu Arg Leu Val Ala Arg Gly Thr Phe Pro Val Leu Val Arg Thr 
1               5                   10                  15      


Ser Ala Cys Arg Ser Leu Phe Gly Pro Val Asp His Glu Glu Leu Ser 
            20                  25                  30          


Arg Glu Leu Gln Ala Arg Leu Ala Glu Leu Asn Ala Glu Asp Gln Asn 
        35                  40                  45              


Arg Trp Asp Tyr Asp Phe Gln Gln Asp Met Pro Leu Arg Gly Pro Gly 
    50                  55                  60                  


Arg Leu Gln Trp Thr Glu Val Asp Ser Asp Ser Val Pro Ala Phe Tyr 
65                  70                  75                  80  


Arg Glu Thr Val Gln Val Gly Arg Cys Arg Leu Leu Leu Ala Pro Arg 
                85                  90                  95      


Pro Val Ala Val Ala Val Ala Val Ser Pro Pro Leu Glu Pro Ala Ala 
            100                 105                 110         


Glu Ser Leu Asp Gly Leu Glu Glu Ala Pro Glu Gln Leu Pro Ser Val 
        115                 120                 125             


Pro Val Pro Ala Pro Ala Ser Thr Pro Pro Pro Val Pro Val Leu Ala 
    130                 135                 140                 


Pro Ala Pro Ala Pro Ala Pro Ala Pro Val Ala Ala Pro Val Ala Ala 
145                 150                 155                 160 


Pro Val Ala Val Ala Val Leu Ala Pro Ala Pro Ala Pro Ala Pro Ala 
                165                 170                 175     


Pro Ala Pro Ala Pro Ala Pro Val Ala Ala Pro Ala Pro Ala Pro Ala 
            180                 185                 190         


Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Asp Ala Ala 
        195                 200                 205             


Pro Gln Glu Ser Ala Glu Gln Gly Ala Asn Gln Gly Gln Arg Gly Gln 
    210                 215                 220                 


Glu Pro Leu Ala Asp Gln Leu His Ser Gly Ile Ser Gly Arg Pro Ala 
225                 230                 235                 240 


Ala Gly Thr Ala Ala Ala Ser Ala Asn Gly Ala Ala Ile Lys Lys Leu 
                245                 250                 255     


Ser Gly Pro Leu Ile Ser Asp Phe Phe Ala Lys Arg Lys Arg Ser Ala 
            260                 265                 270         


Pro Glu Lys Ser Ser Gly Asp Val Pro Ala Pro Cys Pro Ser Pro Ser 
        275                 280                 285             


Ala Ala Pro Gly Val Gly Ser Val Glu Gln Thr Pro Arg Lys Arg Leu 
    290                 295                 300                 


Arg 
305 


<210>  4342
<211>  185
<212>  PRT
<213>  homo sapiens

<400>  4342

Met Asp Ala Ala Glu Val Glu Phe Leu Ala Glu Lys Glu Leu Val Thr 
1               5                   10                  15      


Ile Ile Pro Asn Phe Ser Leu Asp Lys Ile Tyr Leu Ile Gly Gly Asp 
            20                  25                  30          


Leu Gly Pro Phe Asn Pro Gly Leu Pro Val Glu Val Pro Leu Trp Leu 
        35                  40                  45              


Ala Ile Asn Leu Lys Gln Arg Gln Lys Cys Arg Leu Leu Pro Pro Glu 
    50                  55                  60                  


Trp Met Asp Val Glu Lys Leu Glu Lys Met Arg Asp His Glu Arg Lys 
65                  70                  75                  80  


Glu Glu Thr Phe Thr Pro Met Pro Ser Pro Tyr Tyr Met Glu Leu Thr 
                85                  90                  95      


Lys Leu Leu Leu Asn His Ala Ser Asp Asn Ile Pro Lys Ala Asp Glu 
            100                 105                 110         


Ile Arg Thr Leu Val Lys Asp Met Trp Asp Thr Arg Ile Ala Lys Leu 
        115                 120                 125             


Arg Val Ser Ala Asp Ser Phe Val Arg Gln Gln Glu Ala His Ala Lys 
    130                 135                 140                 


Leu Asp Asn Leu Thr Leu Met Glu Ile Asn Thr Ser Gly Thr Phe Leu 
145                 150                 155                 160 


Thr Gln Ala Leu Asn His Met Tyr Lys Leu Arg Thr Asn Leu Gln Pro 
                165                 170                 175     


Leu Glu Ser Thr Gln Ser Gln Asp Phe 
            180                 185 


<210>  4343
<211>  288
<212>  PRT
<213>  homo sapiens

<400>  4343

Met Ala Ala Ala Ala Tyr Val Asp His Phe Ala Ala Glu Cys Leu Val 
1               5                   10                  15      


Ser Met Ser Ser Arg Ala Val Val His Gly Pro Arg Glu Gly Pro Glu 
            20                  25                  30          


Ser Arg Pro Glu Gly Ala Ala Val Ala Ala Thr Pro Thr Leu Pro Arg 
        35                  40                  45              


Val Glu Glu Arg Arg Asp Gly Lys Asp Ser Ala Ser Leu Phe Val Val 
    50                  55                  60                  


Ala Arg Ile Leu Ala Asp Leu Asn Gln Gln Ala Pro Ala Pro Ala Pro 
65                  70                  75                  80  


Ala Glu Arg Arg Glu Gly Ala Ala Ala Arg Lys Ala Arg Thr Pro Cys 
                85                  90                  95      


Arg Leu Pro Pro Pro Ala Pro Glu Pro Thr Ser Pro Gly Ala Glu Gly 
            100                 105                 110         


Ala Ala Ala Ala Pro Pro Ser Pro Ala Trp Ser Glu Pro Glu Pro Glu 
        115                 120                 125             


Ala Gly Leu Glu Pro Glu Arg Glu Pro Gly Pro Ala Gly Ser Gly Glu 
    130                 135                 140                 


Pro Gly Leu Arg Gln Arg Val Arg Arg Gly Arg Ser Arg Ala Asp Leu 
145                 150                 155                 160 


Glu Ser Pro Gln Arg Lys His Lys Cys His Tyr Ala Gly Cys Glu Lys 
                165                 170                 175     


Val Tyr Gly Lys Ser Ser His Leu Lys Ala His Leu Arg Thr His Thr 
            180                 185                 190         


Gly Glu Arg Pro Phe Ala Cys Ser Trp Gln Asp Cys Asn Lys Lys Phe 
        195                 200                 205             


Ala Arg Ser Asp Glu Leu Ala Arg His Tyr Arg Thr His Thr Gly Glu 
    210                 215                 220                 


Lys Lys Phe Ser Cys Pro Ile Cys Glu Lys Arg Phe Met Arg Ser Asp 
225                 230                 235                 240 


His Leu Thr Lys His Ala Arg Arg His Ala Asn Phe His Pro Gly Met 
                245                 250                 255     


Leu Gln Arg Arg Gly Gly Gly Ser Arg Thr Gly Ser Leu Ser Asp Tyr 
            260                 265                 270         


Ser Arg Ser Asp Ala Ser Ser Pro Thr Ile Ser Pro Ala Ser Ser Pro 
        275                 280                 285             


<210>  4344
<211>  292
<212>  PRT
<213>  homo sapiens

<400>  4344

Met Met Ala Phe Ala Pro Pro Lys Asn Thr Asp Gly Pro Lys Met Gln 
1               5                   10                  15      


Thr Lys Met Ser Thr Trp Thr Pro Leu Asn His Gln Leu Leu Asn Asp 
            20                  25                  30          


Arg Val Phe Glu Glu Arg Arg Ala Leu Leu Gly Lys Trp Phe Asp Lys 
        35                  40                  45              


Trp Thr Asp Ser Gln Arg Arg Arg Ile Leu Thr Gly Leu Leu Glu Arg 
    50                  55                  60                  


Cys Ser Leu Ser Gln Gln Lys Phe Cys Cys Arg Lys Leu Gln Glu Lys 
65                  70                  75                  80  


Ile Pro Ala Glu Ala Leu Asp Phe Thr Thr Lys Leu Pro Arg Val Leu 
                85                  90                  95      


Ser Leu Tyr Ile Phe Ser Phe Leu Asp Pro Arg Ser Leu Cys Arg Cys 
            100                 105                 110         


Ala Gln Val Cys Trp His Trp Lys Asn Leu Ala Glu Leu Asp Gln Leu 
        115                 120                 125             


Trp Met Leu Lys Cys Leu Arg Phe Asn Trp Tyr Ile Asn Phe Ser Pro 
    130                 135                 140                 


Thr Pro Phe Glu Gln Gly Ile Trp Lys Lys His Tyr Ile Gln Met Val 
145                 150                 155                 160 


Lys Glu Leu His Ile Thr Lys Pro Lys Thr Pro Pro Lys Asp Gly Phe 
                165                 170                 175     


Val Ile Ala Asp Val Gln Leu Val Thr Ser Asn Ser Pro Glu Glu Lys 
            180                 185                 190         


Gln Ser Pro Leu Ser Ala Phe Arg Ser Ser Ser Ser Leu Arg Lys Lys 
        195                 200                 205             


Asn Asn Ser Gly Glu Lys Ala Leu Pro Pro Trp Arg Ser Ser Asp Lys 
    210                 215                 220                 


His Pro Thr Asp Ile Ile Arg Phe Asn Tyr Leu Asp Asn Arg Asp Pro 
225                 230                 235                 240 


Met Glu Thr Val Gln Gln Gly Arg Arg Lys Arg Asn Gln Met Thr Pro 
                245                 250                 255     


Asp Phe Ser Arg Gln Ser His Asp Lys Lys Asn Lys Leu Gln Asp Arg 
            260                 265                 270         


Thr Arg Leu Arg Lys Ala Gln Ser Met Met Ser Arg Arg Asn Pro Phe 
        275                 280                 285             


Pro Leu Cys Pro 
    290         


<210>  4345
<211>  477
<212>  PRT
<213>  homo sapiens

<400>  4345

Met Phe Pro Val Phe Pro Cys Thr Leu Leu Ala Pro Pro Phe Pro Val 
1               5                   10                  15      


Leu Gly Leu Asp Ser Arg Gly Val Gly Gly Leu Met Asn Ser Phe Pro 
            20                  25                  30          


Pro Pro Gln Gly His Ala Gln Asn Pro Leu Gln Val Gly Ala Glu Leu 
        35                  40                  45              


Gln Ser Arg Phe Phe Ala Ser Gln Gly Cys Ala Gln Ser Pro Phe Gln 
    50                  55                  60                  


Ala Ala Pro Ala Pro Pro Pro Thr Pro Gln Ala Pro Ala Ala Glu Pro 
65                  70                  75                  80  


Leu Gln Val Asp Leu Leu Pro Val Leu Ala Ala Ala Gln Glu Ser Ala 
                85                  90                  95      


Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Val Ala Ala Ala 
            100                 105                 110         


Pro Pro Ala Pro Ala Ala Ala Ser Thr Val Asp Thr Ala Ala Leu Lys 
        115                 120                 125             


Gln Pro Pro Ala Pro Pro Pro Pro Pro Pro Pro Val Ser Ala Pro Ala 
    130                 135                 140                 


Ala Glu Ala Ala Pro Pro Ala Ser Ala Ala Thr Ile Ala Ala Ala Ala 
145                 150                 155                 160 


Ala Thr Ala Val Val Ala Pro Thr Ser Thr Val Ala Val Ala Pro Val 
                165                 170                 175     


Ala Ser Ala Leu Glu Lys Lys Thr Lys Ser Lys Gly Pro Tyr Ile Cys 
            180                 185                 190         


Ala Leu Cys Ala Lys Glu Phe Lys Asn Gly Tyr Asn Leu Arg Arg His 
        195                 200                 205             


Glu Ala Ile His Thr Gly Ala Lys Ala Gly Arg Val Pro Ser Gly Ala 
    210                 215                 220                 


Met Lys Met Pro Thr Met Val Pro Leu Ser Leu Leu Ser Val Pro Gln 
225                 230                 235                 240 


Leu Ser Gly Ala Gly Gly Gly Gly Gly Glu Ala Gly Ala Gly Gly Gly 
                245                 250                 255     


Ala Ala Ala Val Ala Ala Gly Gly Val Val Thr Thr Thr Ala Ser Gly 
            260                 265                 270         


Lys Arg Ile Arg Lys Asn His Ala Cys Glu Met Cys Gly Lys Ala Phe 
        275                 280                 285             


Arg Asp Val Tyr His Leu Asn Arg His Lys Leu Ser His Ser Asp Glu 
    290                 295                 300                 


Lys Pro Tyr Gln Cys Pro Val Cys Gln Gln Arg Phe Lys Arg Lys Asp 
305                 310                 315                 320 


Arg Met Ser Tyr His Val Arg Ser His Asp Gly Ala Val His Lys Pro 
                325                 330                 335     


Tyr Asn Cys Ser His Cys Gly Lys Ser Phe Ser Arg Pro Asp His Leu 
            340                 345                 350         


Asn Ser His Val Arg Gln Val His Ser Thr Glu Arg Pro Phe Lys Cys 
        355                 360                 365             


Glu Lys Cys Glu Ala Ala Phe Ala Thr Lys Asp Arg Leu Arg Ala His 
    370                 375                 380                 


Thr Val Arg His Glu Glu Lys Val Pro Cys His Val Cys Gly Lys Met 
385                 390                 395                 400 


Leu Ser Ser Ala Tyr Ile Ser Asp His Met Lys Val His Ser Gln Gly 
                405                 410                 415     


Pro His His Val Cys Glu Leu Cys Asn Lys Gly Thr Gly Glu Val Cys 
            420                 425                 430         


Pro Met Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala 
        435                 440                 445             


Val Ala Ala Pro Pro Thr Ala Val Gly Ser Leu Ser Gly Ala Glu Gly 
    450                 455                 460                 


Val Pro Val Ser Ser Gln Pro Leu Pro Ser Gln Pro Trp 
465                 470                 475         


<210>  4346
<211>  411
<212>  PRT
<213>  homo sapiens

<400>  4346

Met Arg Arg Arg Arg Ala Gly Gly Arg Thr Met Val Glu Arg Ala Ser 
1               5                   10                  15      


Lys Phe Val Leu Val Val Ala Gly Ser Val Cys Phe Met Leu Ile Leu 
            20                  25                  30          


Tyr Gln Tyr Ala Gly Pro Gly Leu Ser Leu Gly Ala Pro Gly Gly Arg 
        35                  40                  45              


Ala Pro Pro Asp Asp Leu Asp Leu Phe Pro Thr Pro Asp Pro His Tyr 
    50                  55                  60                  


Glu Lys Lys Tyr Tyr Phe Pro Val Arg Glu Leu Glu Arg Ser Leu Arg 
65                  70                  75                  80  


Phe Asp Met Lys Gly Asp Asp Val Ile Val Phe Leu His Ile Gln Lys 
                85                  90                  95      


Thr Gly Gly Thr Thr Phe Gly Arg His Leu Val Gln Asn Val Arg Leu 
            100                 105                 110         


Glu Val Pro Cys Asp Cys Arg Pro Gly Gln Lys Lys Cys Thr Cys Tyr 
        115                 120                 125             


Arg Pro Asn Arg Arg Glu Thr Trp Leu Phe Ser Arg Phe Ser Thr Gly 
    130                 135                 140                 


Trp Ser Cys Gly Leu His Ala Asp Trp Thr Glu Leu Thr Asn Cys Val 
145                 150                 155                 160 


Pro Gly Val Leu Asp Arg Arg Asp Ser Ala Ala Leu Arg Thr Pro Arg 
                165                 170                 175     


Lys Phe Tyr Tyr Ile Thr Leu Leu Arg Asp Pro Val Ser Arg Tyr Leu 
            180                 185                 190         


Ser Glu Trp Arg His Val Gln Arg Gly Ala Thr Trp Lys Thr Ser Leu 
        195                 200                 205             


His Met Cys Asp Gly Arg Thr Pro Thr Pro Glu Glu Leu Pro Pro Cys 
    210                 215                 220                 


Tyr Glu Gly Thr Asp Trp Ser Gly Cys Thr Leu Gln Glu Phe Met Asp 
225                 230                 235                 240 


Cys Pro Tyr Asn Leu Ala Asn Asn Arg Gln Val Arg Met Leu Ala Asp 
                245                 250                 255     


Leu Ser Leu Val Gly Cys Tyr Asn Leu Ser Phe Ile Pro Glu Gly Lys 
            260                 265                 270         


Arg Ala Gln Leu Leu Leu Glu Ser Ala Lys Lys Asn Leu Arg Gly Met 
        275                 280                 285             


Ala Phe Phe Gly Leu Thr Glu Phe Gln Arg Lys Thr Gln Tyr Leu Phe 
    290                 295                 300                 


Glu Arg Thr Phe Asn Leu Lys Phe Ile Arg Pro Phe Met Gln Tyr Asn 
305                 310                 315                 320 


Ser Thr Arg Ala Gly Gly Val Glu Val Asp Glu Asp Thr Ile Arg Arg 
                325                 330                 335     


Ile Glu Glu Leu Asn Asp Leu Asp Met Gln Leu Tyr Asp Tyr Ala Lys 
            340                 345                 350         


Asp Leu Phe Gln Gln Arg Tyr Gln Tyr Lys Arg Gln Leu Glu Arg Arg 
        355                 360                 365             


Glu Gln Arg Leu Arg Ser Arg Glu Glu Arg Leu Leu His Arg Ala Lys 
    370                 375                 380                 


Glu Ala Leu Pro Arg Glu Asp Ala Asp Glu Pro Gly Arg Val Pro Thr 
385                 390                 395                 400 


Glu Asp Tyr Met Ser His Ile Ile Glu Lys Trp 
                405                 410     


<210>  4347
<211>  676
<212>  PRT
<213>  homo sapiens

<400>  4347

Met Ser Asp Gln Ile Lys Phe Ile Met Asp Ser Leu Asn Lys Glu Pro 
1               5                   10                  15      


Phe Arg Lys Asn Tyr Asn Leu Ile Thr Phe Asp Ser Leu Glu Pro Met 
            20                  25                  30          


Gln Leu Leu Gln Val Leu Ser Asp Val Leu Ala Glu Ile Asp Pro Lys 
        35                  40                  45              


Gln Leu Val Asp Ile Arg Glu Glu Met Pro Glu Gln Thr Ala Lys Arg 
    50                  55                  60                  


Met Leu Ser Leu Leu Gly Ile Leu Lys Tyr Lys Pro Ser Gly Asn Ala 
65                  70                  75                  80  


Thr Asp Met Ser Thr Phe Arg Gln Gly Leu Val Ile Gly Ser Lys Pro 
                85                  90                  95      


Val Ile Tyr Pro Val Leu His Trp Leu Leu Gln Arg Thr Asn Glu Leu 
            100                 105                 110         


Lys Lys Arg Ala Tyr Leu Ala Arg Phe Leu Ile Lys Leu Glu Val Pro 
        115                 120                 125             


Ser Glu Phe Leu Gln Asp Glu Thr Val Ala Asp Thr Asn Lys Gln Tyr 
    130                 135                 140                 


Glu Glu Leu Met Glu Ala Phe Lys Thr Leu His Lys Glu Tyr Glu Gln 
145                 150                 155                 160 


Leu Lys Ile Ser Gly Phe Ser Thr Ala Glu Ile Arg Lys Asp Ile Ser 
                165                 170                 175     


Ala Met Glu Glu Glu Lys Asp Gln Leu Ile Lys Arg Val Glu His Leu 
            180                 185                 190         


Lys Lys Arg Val Glu Thr Ala Gln Asn His Gln Trp Met Leu Lys Ile 
        195                 200                 205             


Ala Arg Gln Leu Arg Val Glu Lys Glu Arg Glu Glu Tyr Leu Ala Gln 
    210                 215                 220                 


Gln Lys Gln Glu Gln Lys Asn Gln Leu Phe His Ala Val Gln Arg Leu 
225                 230                 235                 240 


Gln Arg Val Gln Asn Gln Leu Lys Ser Met Arg Gln Ala Ala Ala Asp 
                245                 250                 255     


Ala Lys Pro Glu Ser Leu Met Lys Arg Leu Glu Glu Glu Ile Lys Phe 
            260                 265                 270         


Asn Leu Tyr Met Val Thr Glu Lys Phe Pro Lys Glu Leu Glu Asn Lys 
        275                 280                 285             


Lys Lys Glu Leu His Phe Leu Gln Lys Val Val Ser Glu Pro Ala Met 
    290                 295                 300                 


Gly His Ser Asp Leu Leu Glu Leu Glu Ser Lys Ile Asn Glu Ile Asn 
305                 310                 315                 320 


Thr Glu Ile Asn Gln Leu Ile Glu Lys Lys Met Met Arg Asn Glu Pro 
                325                 330                 335     


Ile Glu Gly Lys Leu Ser Leu Tyr Arg Gln Gln Ala Ser Ile Ile Ser 
            340                 345                 350         


Arg Lys Lys Glu Ala Lys Ala Glu Glu Leu Gln Glu Ala Lys Glu Lys 
        355                 360                 365             


Leu Ala Ser Leu Glu Arg Glu Ala Ser Val Lys Arg Asn Gln Thr Arg 
    370                 375                 380                 


Glu Phe Asp Gly Thr Glu Val Leu Lys Gly Asp Glu Phe Lys Arg Tyr 
385                 390                 395                 400 


Val Asn Lys Leu Arg Ser Lys Ser Thr Val Phe Lys Lys Lys His Gln 
                405                 410                 415     


Ile Ile Ala Glu Leu Lys Ala Glu Phe Gly Leu Leu Gln Arg Thr Glu 
            420                 425                 430         


Glu Leu Leu Lys Gln Arg His Glu Asn Ile Gln Gln Gln Leu Gln Thr 
        435                 440                 445             


Met Glu Glu Lys Lys Gly Ile Ser Gly Tyr Ser Tyr Thr Gln Glu Glu 
    450                 455                 460                 


Leu Glu Arg Val Ser Ala Leu Lys Ser Glu Val Asp Glu Met Lys Gly 
465                 470                 475                 480 


Arg Thr Leu Asp Asp Met Ser Glu Met Val Lys Lys Leu Tyr Ser Leu 
                485                 490                 495     


Val Ser Glu Lys Lys Ser Ala Leu Ala Ser Val Ile Lys Glu Leu Arg 
            500                 505                 510         


Gln Leu Arg Gln Lys Tyr Gln Glu Leu Thr Gln Glu Cys Asp Glu Lys 
        515                 520                 525             


Lys Ser Gln Tyr Asp Ser Cys Ala Ala Gly Leu Glu Ser Asn Arg Ser 
    530                 535                 540                 


Lys Leu Glu Gln Glu Val Arg Arg Leu Arg Glu Glu Cys Leu Gln Glu 
545                 550                 555                 560 


Glu Ser Arg Tyr His Tyr Thr Asn Cys Met Ile Lys Asn Leu Glu Val 
                565                 570                 575     


Gln Leu Arg Arg Ala Thr Asp Glu Met Lys Ala Tyr Ile Ser Ser Asp 
            580                 585                 590         


Gln Gln Glu Lys Arg Lys Ala Ile Arg Glu Gln Tyr Thr Lys Asn Thr 
        595                 600                 605             


Ala Glu Gln Glu Asn Leu Gly Lys Lys Leu Arg Glu Lys Gln Lys Val 
    610                 615                 620                 


Ile Arg Glu Ser His Gly Pro Asn Met Lys Gln Ala Lys Met Trp Arg 
625                 630                 635                 640 


Asp Leu Glu Gln Leu Met Glu Cys Lys Lys Gln Cys Phe Leu Lys Gln 
                645                 650                 655     


Gln Ser Gln Thr Ser Ile Gly Gln Val Ile Gln Glu Gly Gly Glu Asp 
            660                 665                 670         


Arg Leu Ile Leu 
        675     


<210>  4348
<211>  812
<212>  PRT
<213>  homo sapiens

<400>  4348

Met Thr Gly Leu Glu Asp Gln Glu Phe Asp Phe Glu Phe Leu Phe Glu 
1               5                   10                  15      


Phe Asn Gln Arg Asp Glu Gly Ala Ala Ala Ala Ala Pro Glu His Tyr 
            20                  25                  30          


Gly Tyr Ala Ser Ser Asn Val Ser Pro Ala Leu Pro Leu Pro Thr Ala 
        35                  40                  45              


His Ser Thr Leu Pro Ala Pro Cys His Asn Leu Gln Thr Ser Thr Pro 
    50                  55                  60                  


Gly Ile Ile Pro Pro Ala Asp His Pro Ser Gly Tyr Gly Ala Ala Leu 
65                  70                  75                  80  


Asp Gly Gly Pro Ala Gly Tyr Phe Leu Ser Ser Gly His Thr Arg Pro 
                85                  90                  95      


Asp Gly Ala Pro Ala Leu Glu Ser Pro Arg Ile Glu Ile Thr Ser Cys 
            100                 105                 110         


Leu Gly Leu Tyr His Asn Asn Asn Gln Phe Phe His Asp Val Glu Val 
        115                 120                 125             


Glu Asp Val Leu Pro Ser Ser Lys Arg Ser Pro Ser Thr Ala Thr Leu 
    130                 135                 140                 


Ser Leu Pro Ser Leu Glu Ala Tyr Arg Asp Pro Ser Cys Leu Ser Pro 
145                 150                 155                 160 


Ala Ser Ser Leu Ser Ser Arg Ser Cys Asn Ser Glu Ala Ser Ser Tyr 
                165                 170                 175     


Glu Ser Asn Tyr Ser Tyr Pro Tyr Ala Ser Pro Gln Thr Ser Pro Trp 
            180                 185                 190         


Gln Ser Pro Cys Val Ser Pro Lys Thr Thr Asp Pro Glu Glu Gly Phe 
        195                 200                 205             


Pro Arg Gly Leu Gly Ala Cys Thr Leu Leu Gly Ser Pro Arg His Ser 
    210                 215                 220                 


Pro Ser Thr Ser Pro Arg Ala Ser Val Thr Glu Glu Ser Trp Leu Gly 
225                 230                 235                 240 


Ala Arg Ser Ser Arg Pro Ala Ser Pro Cys Asn Lys Arg Lys Tyr Ser 
                245                 250                 255     


Leu Asn Gly Arg Gln Pro Pro Tyr Ser Pro His His Ser Pro Thr Pro 
            260                 265                 270         


Ser Pro His Gly Ser Pro Arg Val Ser Val Thr Asp Asp Ser Trp Leu 
        275                 280                 285             


Gly Asn Thr Thr Gln Tyr Thr Ser Ser Ala Ile Val Ala Ala Ile Asn 
    290                 295                 300                 


Ala Leu Thr Thr Asp Ser Ser Leu Asp Leu Gly Asp Gly Val Pro Val 
305                 310                 315                 320 


Lys Ser Arg Lys Thr Thr Leu Glu Gln Pro Pro Ser Val Ala Leu Lys 
                325                 330                 335     


Val Glu Pro Val Gly Glu Asp Leu Gly Ser Pro Pro Pro Pro Ala Asp 
            340                 345                 350         


Phe Ala Pro Glu Asp Tyr Ser Ser Phe Gln His Ile Arg Lys Gly Gly 
        355                 360                 365             


Phe Cys Asp Gln Tyr Leu Ala Val Pro Gln His Pro Tyr Gln Trp Ala 
    370                 375                 380                 


Lys Pro Lys Pro Leu Ser Pro Thr Ser Tyr Met Ser Pro Thr Leu Pro 
385                 390                 395                 400 


Ala Leu Asp Trp Gln Leu Pro Ser His Ser Gly Pro Tyr Glu Leu Arg 
                405                 410                 415     


Ile Glu Val Gln Pro Lys Ser His His Arg Ala His Tyr Glu Thr Glu 
            420                 425                 430         


Gly Ser Arg Gly Ala Val Lys Ala Ser Ala Gly Gly His Pro Ile Val 
        435                 440                 445             


Gln Leu His Gly Tyr Leu Glu Asn Glu Pro Leu Met Leu Gln Leu Phe 
    450                 455                 460                 


Ile Gly Thr Ala Asp Asp Arg Leu Leu Arg Pro His Ala Phe Tyr Gln 
465                 470                 475                 480 


Val His Arg Ile Thr Gly Lys Thr Val Ser Thr Thr Ser His Glu Ala 
                485                 490                 495     


Ile Leu Ser Asn Thr Lys Val Leu Glu Ile Pro Leu Leu Pro Glu Asn 
            500                 505                 510         


Ser Met Arg Ala Val Ile Asp Cys Ala Gly Ile Leu Lys Leu Arg Asn 
        515                 520                 525             


Ser Asp Ile Glu Leu Arg Lys Gly Glu Thr Asp Ile Gly Arg Lys Asn 
    530                 535                 540                 


Thr Arg Val Arg Leu Val Phe Arg Val His Val Pro Gln Pro Ser Gly 
545                 550                 555                 560 


Arg Thr Leu Ser Leu Gln Val Ala Ser Asn Pro Ile Glu Cys Ser Gln 
                565                 570                 575     


Arg Ser Ala Gln Glu Leu Pro Leu Val Glu Lys Gln Ser Thr Asp Ser 
            580                 585                 590         


Tyr Pro Val Val Gly Gly Lys Lys Met Val Leu Ser Gly His Asn Phe 
        595                 600                 605             


Leu Gln Asp Ser Lys Val Ile Phe Val Glu Lys Ala Pro Asp Gly His 
    610                 615                 620                 


His Val Trp Glu Met Glu Ala Lys Thr Asp Arg Asp Leu Cys Lys Pro 
625                 630                 635                 640 


Asn Ser Leu Val Val Glu Ile Pro Pro Phe Arg Asn Gln Arg Ile Thr 
                645                 650                 655     


Ser Pro Val His Val Ser Phe Tyr Val Cys Asn Gly Lys Arg Lys Arg 
            660                 665                 670         


Ser Gln Tyr Gln Arg Phe Thr Tyr Leu Pro Ala Asn Val Pro Ile Ile 
        675                 680                 685             


Lys Thr Glu Pro Thr Asp Asp Tyr Glu Pro Ala Pro Thr Cys Gly Pro 
    690                 695                 700                 


Val Ser Gln Gly Leu Ser Pro Leu Pro Arg Pro Tyr Tyr Ser Gln Gln 
705                 710                 715                 720 


Leu Ala Met Pro Pro Asp Pro Ser Ser Cys Leu Val Ala Gly Phe Pro 
                725                 730                 735     


Pro Cys Pro Gln Arg Ser Thr Leu Met Pro Ala Ala Pro Gly Val Ser 
            740                 745                 750         


Pro Lys Leu His Asp Leu Ser Pro Ala Ala Tyr Thr Lys Gly Val Ala 
        755                 760                 765             


Ser Pro Gly His Cys His Leu Gly Leu Pro Gln Pro Ala Gly Glu Ala 
    770                 775                 780                 


Pro Ala Val Gln Asp Val Pro Arg Pro Val Ala Thr His Pro Gly Ser 
785                 790                 795                 800 


Pro Gly Gln Pro Pro Pro Ala Leu Leu Pro Gln Gln 
                805                 810         


<210>  4349
<211>  468
<212>  PRT
<213>  homo sapiens

<400>  4349

Met Gly Phe Leu Gly Thr Gly Thr Trp Ile Leu Val Leu Val Leu Pro 
1               5                   10                  15      


Ile Gln Ala Phe Pro Lys Pro Gly Gly Ser Gln Asp Lys Ser Leu His 
            20                  25                  30          


Asn Arg Glu Leu Ser Ala Glu Arg Pro Leu Asn Glu Gln Ile Ala Glu 
        35                  40                  45              


Ala Glu Glu Asp Lys Ile Lys Lys Thr Tyr Pro Pro Glu Asn Lys Pro 
    50                  55                  60                  


Gly Gln Ser Asn Tyr Ser Phe Val Asp Asn Leu Asn Leu Leu Lys Ala 
65                  70                  75                  80  


Ile Thr Glu Lys Glu Lys Ile Glu Lys Glu Arg Gln Ser Ile Arg Ser 
                85                  90                  95      


Ser Pro Leu Asp Asn Lys Leu Asn Val Glu Asp Val Asp Ser Thr Lys 
            100                 105                 110         


Asn Arg Lys Leu Ile Asp Asp Tyr Asp Ser Thr Lys Ser Gly Leu Asp 
        115                 120                 125             


His Lys Phe Gln Asp Asp Pro Asp Gly Leu His Gln Leu Asp Gly Thr 
    130                 135                 140                 


Pro Leu Thr Ala Glu Asp Ile Val His Lys Ile Ala Ala Arg Ile Tyr 
145                 150                 155                 160 


Glu Glu Asn Asp Arg Ala Val Phe Asp Lys Ile Val Ser Lys Leu Leu 
                165                 170                 175     


Asn Leu Gly Leu Ile Thr Glu Ser Gln Ala His Thr Leu Glu Asp Glu 
            180                 185                 190         


Val Ala Glu Val Leu Gln Lys Leu Ile Ser Lys Glu Ala Asn Asn Tyr 
        195                 200                 205             


Glu Glu Asp Pro Asn Lys Pro Thr Ser Trp Thr Glu Asn Gln Ala Gly 
    210                 215                 220                 


Lys Ile Pro Glu Lys Val Thr Pro Met Ala Ala Ile Gln Asp Gly Leu 
225                 230                 235                 240 


Ala Lys Gly Glu Asn Asp Glu Thr Val Ser Asn Thr Leu Thr Leu Thr 
                245                 250                 255     


Asn Gly Leu Glu Arg Arg Thr Lys Thr Tyr Ser Glu Asp Asn Phe Glu 
            260                 265                 270         


Glu Leu Gln Tyr Phe Pro Asn Phe Tyr Ala Leu Leu Lys Ser Ile Asp 
        275                 280                 285             


Ser Glu Lys Glu Ala Lys Glu Lys Glu Thr Leu Ile Thr Ile Met Lys 
    290                 295                 300                 


Thr Leu Ile Asp Phe Val Lys Met Met Val Lys Tyr Gly Thr Ile Ser 
305                 310                 315                 320 


Pro Glu Glu Gly Val Ser Tyr Leu Glu Asn Leu Asp Glu Met Ile Ala 
                325                 330                 335     


Leu Gln Thr Lys Asn Lys Leu Glu Lys Asn Ala Thr Asp Asn Ile Ser 
            340                 345                 350         


Lys Leu Phe Pro Ala Pro Ser Glu Lys Ser His Glu Glu Thr Asp Ser 
        355                 360                 365             


Thr Lys Glu Glu Ala Ala Lys Met Glu Lys Glu Tyr Gly Ser Leu Lys 
    370                 375                 380                 


Asp Ser Thr Lys Asp Asp Asn Ser Asn Pro Gly Gly Lys Thr Asp Glu 
385                 390                 395                 400 


Pro Lys Gly Lys Thr Glu Ala Tyr Leu Glu Ala Ile Arg Lys Asn Ile 
                405                 410                 415     


Glu Trp Leu Lys Lys His Asp Lys Lys Gly Asn Lys Glu Asp Tyr Asp 
            420                 425                 430         


Leu Ser Lys Met Arg Asp Phe Ile Asn Lys Gln Ala Asp Ala Tyr Val 
        435                 440                 445             


Glu Lys Gly Ile Leu Asp Lys Glu Glu Ala Glu Ala Ile Lys Arg Ile 
    450                 455                 460                 


Tyr Ser Ser Leu 
465             


<210>  4350
<211>  236
<212>  PRT
<213>  homo sapiens

<400>  4350

Met Ala Ala Ile Gln Asp Gly Leu Ala Lys Gly Glu Asn Asp Glu Thr 
1               5                   10                  15      


Val Ser Asn Thr Leu Thr Leu Thr Asn Gly Leu Glu Arg Arg Thr Lys 
            20                  25                  30          


Thr Tyr Ser Glu Asp Asn Phe Glu Glu Leu Gln Tyr Phe Pro Asn Phe 
        35                  40                  45              


Tyr Ala Leu Leu Lys Ser Ile Asp Ser Glu Lys Glu Ala Lys Glu Lys 
    50                  55                  60                  


Glu Thr Leu Ile Thr Ile Met Lys Thr Leu Ile Asp Phe Val Lys Met 
65                  70                  75                  80  


Met Val Lys Tyr Gly Thr Ile Ser Pro Glu Glu Gly Val Ser Tyr Leu 
                85                  90                  95      


Glu Asn Leu Asp Glu Met Ile Ala Leu Gln Thr Lys Asn Lys Leu Glu 
            100                 105                 110         


Lys Asn Ala Thr Asp Asn Ile Ser Lys Leu Phe Pro Ala Pro Ser Glu 
        115                 120                 125             


Lys Ser His Glu Glu Thr Asp Ser Thr Lys Glu Glu Ala Ala Lys Met 
    130                 135                 140                 


Glu Lys Glu Tyr Gly Ser Leu Lys Asp Ser Thr Lys Asp Asp Asn Ser 
145                 150                 155                 160 


Asn Pro Gly Gly Lys Thr Asp Glu Pro Lys Gly Lys Thr Glu Ala Tyr 
                165                 170                 175     


Leu Glu Ala Ile Arg Lys Asn Ile Glu Trp Leu Lys Lys His Asp Lys 
            180                 185                 190         


Lys Gly Asn Lys Glu Asp Tyr Asp Leu Ser Lys Met Arg Asp Phe Ile 
        195                 200                 205             


Asn Lys Gln Ala Asp Ala Tyr Val Glu Lys Gly Ile Leu Asp Lys Glu 
    210                 215                 220                 


Glu Ala Glu Ala Ile Lys Arg Ile Tyr Ser Ser Leu 
225                 230                 235     


<210>  4351
<211>  75
<212>  PRT
<213>  homo sapiens

<400>  4351

Met Lys Ala Thr Ile Ile Leu Leu Leu Leu Ala Gln Val Ser Trp Ala 
1               5                   10                  15      


Gly Pro Phe Gln Gln Arg Gly Leu Phe Asp Phe Met Leu Glu Asp Glu 
            20                  25                  30          


Ala Ser Gly Ile Gly Pro Glu Val Pro Asp Asp Arg Asp Phe Glu Pro 
        35                  40                  45              


Ser Leu Gly Pro Val Cys Pro Phe Arg Cys Gln Cys His Leu Arg Val 
    50                  55                  60                  


Val Gln Cys Ser Asp Leu Gly Cys Leu Pro Ser 
65                  70                  75  


<210>  4352
<211>  1051
<212>  PRT
<213>  homo sapiens

<400>  4352

Met Lys Ser Glu Asp Tyr Pro His Glu Thr Met Ala Pro Asp Ile His 
1               5                   10                  15      


Glu Glu Arg Gln Tyr Arg Cys Glu Asp Cys Asp Gln Leu Phe Glu Ser 
            20                  25                  30          


Lys Ala Glu Leu Ala Asp His Gln Lys Phe Pro Cys Ser Thr Pro His 
        35                  40                  45              


Ser Ala Phe Ser Met Val Glu Glu Asp Phe Gln Gln Lys Leu Glu Ser 
    50                  55                  60                  


Glu Asn Asp Leu Gln Glu Ile His Thr Ile Gln Glu Cys Lys Glu Cys 
65                  70                  75                  80  


Asp Gln Val Phe Pro Asp Leu Gln Ser Leu Glu Lys His Met Leu Ser 
                85                  90                  95      


His Thr Glu Glu Arg Glu Tyr Lys Cys Asp Gln Cys Pro Lys Ala Phe 
            100                 105                 110         


Asn Trp Lys Ser Asn Leu Ile Arg His Gln Met Ser His Asp Ser Gly 
        115                 120                 125             


Lys His Tyr Glu Cys Glu Asn Cys Ala Lys Val Phe Thr Asp Pro Ser 
    130                 135                 140                 


Asn Leu Gln Arg His Ile Arg Ser Gln His Val Gly Ala Arg Ala His 
145                 150                 155                 160 


Ala Cys Pro Glu Cys Gly Lys Thr Phe Ala Thr Ser Ser Gly Leu Lys 
                165                 170                 175     


Gln His Lys His Ile His Ser Ser Val Lys Pro Phe Ile Cys Glu Val 
            180                 185                 190         


Cys His Lys Ser Tyr Thr Gln Phe Ser Asn Leu Cys Arg His Lys Arg 
        195                 200                 205             


Met His Ala Asp Cys Arg Thr Gln Ile Lys Cys Lys Asp Cys Gly Gln 
    210                 215                 220                 


Met Phe Ser Thr Thr Ser Ser Leu Asn Lys His Arg Arg Phe Cys Glu 
225                 230                 235                 240 


Gly Lys Asn His Phe Ala Ala Gly Gly Phe Phe Gly Gln Gly Ile Ser 
                245                 250                 255     


Leu Pro Gly Thr Pro Ala Met Asp Lys Thr Ser Met Val Asn Met Ser 
            260                 265                 270         


His Ala Asn Pro Gly Leu Ala Asp Tyr Phe Gly Ala Asn Arg His Pro 
        275                 280                 285             


Ala Gly Leu Thr Phe Pro Thr Ala Pro Gly Phe Ser Phe Ser Phe Pro 
    290                 295                 300                 


Gly Leu Phe Pro Ser Gly Leu Tyr His Arg Pro Pro Leu Ile Pro Ala 
305                 310                 315                 320 


Ser Ser Pro Val Lys Gly Leu Ser Ser Thr Glu Gln Thr Asn Lys Ser 
                325                 330                 335     


Gln Ser Pro Leu Met Thr His Pro Gln Ile Leu Pro Ala Thr Gln Asp 
            340                 345                 350         


Ile Leu Lys Ala Leu Ser Lys His Pro Ser Val Gly Asp Asn Lys Pro 
        355                 360                 365             


Val Glu Leu Gln Pro Glu Arg Ser Ser Glu Glu Arg Pro Phe Glu Lys 
    370                 375                 380                 


Ile Ser Asp Gln Ser Glu Ser Ser Asp Leu Asp Asp Val Ser Thr Pro 
385                 390                 395                 400 


Ser Gly Ser Asp Leu Glu Thr Thr Ser Gly Ser Asp Leu Glu Ser Asp 
                405                 410                 415     


Ile Glu Ser Asp Lys Glu Lys Phe Lys Glu Asn Gly Lys Met Phe Lys 
            420                 425                 430         


Asp Lys Val Ser Pro Leu Gln Asn Leu Ala Ser Ile Asn Asn Lys Lys 
        435                 440                 445             


Glu Tyr Ser Asn His Ser Ile Phe Ser Pro Ser Leu Glu Glu Gln Thr 
    450                 455                 460                 


Ala Val Ser Gly Ala Val Asn Asp Ser Ile Lys Ala Ile Ala Ser Ile 
465                 470                 475                 480 


Ala Glu Lys Tyr Phe Gly Ser Thr Gly Leu Val Gly Leu Gln Asp Lys 
                485                 490                 495     


Lys Val Gly Ala Leu Pro Tyr Pro Ser Met Phe Pro Leu Pro Phe Phe 
            500                 505                 510         


Pro Ala Phe Ser Gln Ser Met Tyr Pro Phe Pro Asp Arg Asp Leu Arg 
        515                 520                 525             


Ser Leu Pro Leu Lys Met Glu Pro Gln Ser Pro Gly Glu Val Lys Lys 
    530                 535                 540                 


Leu Gln Lys Gly Ser Ser Glu Ser Pro Phe Asp Leu Thr Thr Lys Arg 
545                 550                 555                 560 


Lys Asp Glu Lys Pro Leu Thr Pro Val Pro Ser Lys Pro Pro Val Thr 
                565                 570                 575     


Pro Ala Thr Ser Gln Asp Gln Pro Leu Asp Leu Ser Met Gly Ser Arg 
            580                 585                 590         


Ser Arg Ala Ser Gly Thr Lys Leu Thr Glu Pro Arg Lys Asn His Val 
        595                 600                 605             


Phe Gly Gly Lys Lys Gly Ser Asn Val Glu Ser Arg Pro Ala Ser Asp 
    610                 615                 620                 


Gly Ser Leu Gln His Ala Arg Pro Thr Pro Phe Phe Met Asp Pro Ile 
625                 630                 635                 640 


Tyr Arg Val Glu Lys Arg Lys Leu Thr Asp Pro Leu Glu Ala Leu Lys 
                645                 650                 655     


Glu Lys Tyr Leu Arg Pro Ser Pro Gly Phe Leu Phe His Pro Gln Phe 
            660                 665                 670         


Gln Leu Pro Asp Gln Arg Thr Trp Met Ser Ala Ile Glu Asn Met Ala 
        675                 680                 685             


Glu Lys Leu Glu Ser Phe Ser Ala Leu Lys Pro Glu Ala Ser Glu Leu 
    690                 695                 700                 


Leu Gln Ser Val Pro Ser Met Phe Asn Phe Arg Ala Pro Pro Asn Ala 
705                 710                 715                 720 


Leu Pro Glu Asn Leu Leu Arg Lys Gly Lys Glu Arg Tyr Thr Cys Arg 
                725                 730                 735     


Tyr Cys Gly Lys Ile Phe Pro Arg Ser Ala Asn Leu Thr Arg His Leu 
            740                 745                 750         


Arg Thr His Thr Gly Glu Gln Pro Tyr Arg Cys Lys Tyr Cys Asp Arg 
        755                 760                 765             


Ser Phe Ser Ile Ser Ser Asn Leu Gln Arg His Val Arg Asn Ile His 
    770                 775                 780                 


Asn Lys Glu Lys Pro Phe Lys Cys His Leu Cys Asp Arg Cys Phe Gly 
785                 790                 795                 800 


Gln Gln Thr Asn Leu Asp Arg His Leu Lys Lys His Glu Asn Gly Asn 
                805                 810                 815     


Met Ser Gly Thr Ala Thr Ser Ser Pro His Ser Glu Leu Glu Ser Thr 
            820                 825                 830         


Gly Ala Ile Leu Asp Asp Lys Glu Asp Ala Tyr Phe Thr Glu Ile Arg 
        835                 840                 845             


Asn Phe Ile Gly Asn Ser Asn His Gly Ser Gln Ser Pro Arg Asn Val 
    850                 855                 860                 


Glu Glu Arg Met Asn Gly Ser His Phe Lys Asp Glu Lys Ala Leu Val 
865                 870                 875                 880 


Thr Ser Gln Asn Ser Asp Leu Leu Asp Asp Glu Glu Val Glu Asp Glu 
                885                 890                 895     


Val Leu Leu Asp Glu Glu Asp Glu Asp Asn Asp Ile Thr Gly Lys Thr 
            900                 905                 910         


Gly Lys Glu Pro Val Thr Ser Asn Leu His Glu Gly Asn Pro Glu Asp 
        915                 920                 925             


Asp Tyr Glu Glu Thr Ser Ala Leu Glu Met Ser Cys Lys Thr Ser Pro 
    930                 935                 940                 


Val Arg Tyr Lys Glu Glu Glu Tyr Lys Ser Gly Leu Ser Ala Leu Asp 
945                 950                 955                 960 


His Ile Arg His Phe Thr Asp Ser Leu Lys Met Arg Lys Met Glu Asp 
                965                 970                 975     


Asn Gln Tyr Ser Glu Ala Glu Leu Ser Ser Phe Ser Thr Ser His Val 
            980                 985                 990         


Pro Glu Glu Leu Lys Gln Pro Leu  His Arg Lys Ser Lys  Ser Gln Ala 
        995                 1000                 1005             


Tyr Ala  Met Met Leu Ser Leu  Ser Asp Lys Glu Ser  Leu His Ser 
    1010                 1015                 1020             


Thr Ser  His Ser Ser Ser Asn  Val Trp His Ser Met  Ala Arg Ala 
    1025                 1030                 1035             


Ala Ala  Glu Ser Ser Ala Ile  Gln Ser Ile Ser His  Val 
    1040                 1045                 1050     


<210>  4353
<211>  603
<212>  PRT
<213>  homo sapiens

<400>  4353

Met Ala Gly Thr Val Arg Thr Ala Cys Leu Val Val Ala Met Leu Leu 
1               5                   10                  15      


Ser Leu Asp Phe Pro Gly Gln Ala Gln Pro Pro Pro Pro Pro Pro Asp 
            20                  25                  30          


Ala Thr Cys His Gln Val Arg Ser Phe Phe Gln Arg Leu Gln Pro Gly 
        35                  40                  45              


Leu Lys Trp Val Pro Glu Thr Pro Val Pro Gly Ser Asp Leu Gln Val 
    50                  55                  60                  


Cys Leu Pro Lys Gly Pro Thr Cys Cys Ser Arg Lys Met Glu Glu Lys 
65                  70                  75                  80  


Tyr Gln Leu Thr Ala Arg Leu Asn Met Glu Gln Leu Leu Gln Ser Ala 
                85                  90                  95      


Ser Met Glu Leu Lys Phe Leu Ile Ile Gln Asn Ala Ala Val Phe Gln 
            100                 105                 110         


Glu Ala Phe Glu Ile Val Val Arg His Ala Lys Asn Tyr Thr Asn Ala 
        115                 120                 125             


Met Phe Lys Asn Asn Tyr Pro Ser Leu Thr Pro Gln Ala Phe Glu Phe 
    130                 135                 140                 


Val Gly Glu Phe Phe Thr Asp Val Ser Leu Tyr Ile Leu Gly Ser Asp 
145                 150                 155                 160 


Ile Asn Val Asp Asp Met Val Asn Glu Leu Phe Asp Ser Leu Phe Pro 
                165                 170                 175     


Val Ile Tyr Thr Gln Leu Met Asn Pro Gly Leu Pro Asp Ser Ala Leu 
            180                 185                 190         


Asp Ile Asn Glu Cys Leu Arg Gly Ala Arg Arg Asp Leu Lys Val Phe 
        195                 200                 205             


Gly Asn Phe Pro Lys Leu Ile Met Thr Gln Val Ser Lys Ser Leu Gln 
    210                 215                 220                 


Val Thr Arg Ile Phe Leu Gln Ala Leu Asn Leu Gly Ile Glu Val Ile 
225                 230                 235                 240 


Asn Thr Thr Asp His Leu Lys Phe Ser Lys Asp Cys Gly Arg Met Leu 
                245                 250                 255     


Thr Arg Met Trp Tyr Cys Ser Tyr Cys Gln Gly Leu Met Met Val Lys 
            260                 265                 270         


Pro Cys Gly Gly Tyr Cys Asn Val Val Met Gln Gly Cys Met Ala Gly 
        275                 280                 285             


Val Val Glu Ile Asp Lys Tyr Trp Arg Glu Tyr Ile Leu Ser Leu Glu 
    290                 295                 300                 


Glu Leu Val Asn Gly Met Tyr Arg Ile Tyr Asp Met Glu Asn Val Leu 
305                 310                 315                 320 


Leu Gly Leu Phe Ser Thr Ile His Asp Ser Ile Gln Tyr Val Gln Lys 
                325                 330                 335     


Asn Ala Gly Lys Leu Thr Thr Thr Glu Thr Glu Lys Lys Ile Trp His 
            340                 345                 350         


Phe Lys Tyr Pro Ile Phe Phe Leu Cys Ile Gly Leu Asp Leu Gln Ile 
        355                 360                 365             


Gly Lys Leu Cys Ala His Ser Gln Gln Arg Gln Tyr Arg Ser Ala Tyr 
    370                 375                 380                 


Tyr Pro Glu Asp Leu Phe Ile Asp Lys Lys Val Leu Lys Val Ala His 
385                 390                 395                 400 


Val Glu His Glu Glu Thr Leu Ser Ser Arg Arg Arg Glu Leu Ile Gln 
                405                 410                 415     


Lys Leu Lys Ser Phe Ile Ser Phe Tyr Ser Ala Leu Pro Gly Tyr Ile 
            420                 425                 430         


Cys Ser His Ser Pro Val Ala Glu Asn Asp Thr Leu Cys Trp Asn Gly 
        435                 440                 445             


Gln Glu Leu Val Glu Arg Tyr Ser Gln Lys Ala Ala Arg Asn Gly Met 
    450                 455                 460                 


Lys Asn Gln Phe Asn Leu His Glu Leu Lys Met Lys Gly Pro Glu Pro 
465                 470                 475                 480 


Val Val Ser Gln Ile Ile Asp Lys Leu Lys His Ile Asn Gln Leu Leu 
                485                 490                 495     


Arg Thr Met Ser Met Pro Lys Gly Arg Val Leu Asp Lys Asn Leu Asp 
            500                 505                 510         


Glu Glu Gly Phe Glu Ser Gly Asp Cys Gly Asp Asp Glu Asp Glu Cys 
        515                 520                 525             


Ile Gly Gly Ser Gly Asp Gly Met Ile Lys Val Lys Asn Gln Leu Arg 
    530                 535                 540                 


Phe Leu Ala Glu Leu Ala Tyr Asp Leu Asp Val Asp Asp Ala Pro Gly 
545                 550                 555                 560 


Asn Ser Gln Gln Ala Thr Pro Lys Asp Asn Glu Ile Ser Thr Phe His 
                565                 570                 575     


Asn Leu Gly Asn Val His Ser Pro Leu Lys Leu Leu Thr Ser Met Ala 
            580                 585                 590         


Ile Ser Val Val Cys Phe Phe Phe Leu Val His 
        595                 600             


<210>  4354
<211>  500
<212>  PRT
<213>  homo sapiens

<400>  4354

Met Ala Thr Ala Ala Ser Asn Pro Tyr Leu Pro Gly Asn Ser Leu Leu 
1               5                   10                  15      


Ala Ala Gly Ser Ile Val His Ser Asp Ala Ala Gly Ala Gly Gly Gly 
            20                  25                  30          


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Gly Gly Gly Gly 
        35                  40                  45              


Gly Gly Met Gln Pro Gly Ser Ala Ala Val Thr Ser Gly Ala Tyr Arg 
    50                  55                  60                  


Gly Asp Pro Ser Ser Val Lys Met Val Gln Ser Asp Phe Met Gln Gly 
65                  70                  75                  80  


Ala Met Ala Ala Ser Asn Gly Gly His Met Leu Ser His Ala His Gln 
                85                  90                  95      


Trp Val Thr Ala Leu Pro His Ala Ala Ala Ala Ala Ala Ala Ala Ala 
            100                 105                 110         


Ala Ala Ala Val Glu Ala Ser Ser Pro Trp Ser Gly Ser Ala Val Gly 
        115                 120                 125             


Met Ala Gly Ser Pro Gln Gln Pro Pro Gln Pro Pro Pro Pro Pro Pro 
    130                 135                 140                 


Gln Gly Pro Asp Val Lys Gly Gly Ala Gly Arg Asp Asp Leu His Ala 
145                 150                 155                 160 


Gly Thr Ala Leu His His Arg Gly Pro Pro His Leu Gly Pro Pro Pro 
                165                 170                 175     


Pro Pro Pro His Gln Gly His Pro Gly Gly Trp Gly Ala Ala Ala Ala 
            180                 185                 190         


Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala His Leu Pro Ser 
        195                 200                 205             


Met Ala Gly Gly Gln Gln Pro Pro Pro Gln Ser Leu Leu Tyr Ser Gln 
    210                 215                 220                 


Pro Gly Gly Phe Thr Val Asn Gly Met Leu Ser Ala Pro Pro Gly Pro 
225                 230                 235                 240 


Gly Gly Gly Gly Gly Gly Ala Gly Gly Gly Ala Gln Ser Leu Val His 
                245                 250                 255     


Pro Gly Leu Val Arg Gly Asp Thr Pro Glu Leu Ala Glu His His His 
            260                 265                 270         


His His His His His Ala His Pro His Pro Pro His Pro His His Ala 
        275                 280                 285             


Gln Gly Pro Pro His His Gly Gly Gly Gly Gly Gly Ala Gly Pro Gly 
    290                 295                 300                 


Leu Asn Ser His Asp Pro His Ser Asp Glu Asp Thr Pro Thr Ser Asp 
305                 310                 315                 320 


Asp Leu Glu Gln Phe Ala Lys Gln Phe Lys Gln Arg Arg Ile Lys Leu 
                325                 330                 335     


Gly Phe Thr Gln Ala Asp Val Gly Leu Ala Leu Gly Thr Leu Tyr Gly 
            340                 345                 350         


Asn Val Phe Ser Gln Thr Thr Ile Cys Arg Phe Glu Ala Leu Gln Leu 
        355                 360                 365             


Ser Phe Lys Asn Met Cys Lys Leu Lys Pro Leu Leu Asn Lys Trp Leu 
    370                 375                 380                 


Glu Glu Ala Asp Ser Ser Thr Gly Ser Pro Thr Ser Ile Asp Lys Ile 
385                 390                 395                 400 


Ala Ala Gln Gly Arg Lys Arg Lys Lys Arg Thr Ser Ile Glu Val Ser 
                405                 410                 415     


Val Lys Gly Ala Leu Glu Ser His Phe Leu Lys Cys Pro Lys Pro Ser 
            420                 425                 430         


Ala Gln Glu Ile Thr Asn Leu Ala Asp Ser Leu Gln Leu Glu Lys Glu 
        435                 440                 445             


Val Val Arg Val Trp Phe Cys Asn Arg Arg Gln Lys Glu Lys Arg Met 
    450                 455                 460                 


Thr Pro Pro Gly Ile Gln Gln Gln Thr Pro Asp Asp Val Tyr Ser Gln 
465                 470                 475                 480 


Val Gly Thr Val Ser Ala Asp Thr Pro Pro Pro His His Gly Leu Gln 
                485                 490                 495     


Thr Ser Val Gln 
            500 


<210>  4355
<211>  727
<212>  PRT
<213>  homo sapiens

<400>  4355

Met Ala Phe Gln Lys Ala Val Lys Gly Thr Ile Leu Val Gly Gly Gly 
1               5                   10                  15      


Ala Leu Ala Thr Val Leu Gly Leu Ser Gln Phe Ala His Tyr Arg Arg 
            20                  25                  30          


Lys Gln Met Asn Leu Ala Tyr Val Lys Ala Ala Asp Cys Ile Ser Glu 
        35                  40                  45              


Pro Val Asn Arg Glu Pro Pro Ser Arg Glu Ala Gln Leu Leu Thr Leu 
    50                  55                  60                  


Gln Asn Thr Ser Glu Phe Asp Ile Leu Val Ile Gly Gly Gly Ala Thr 
65                  70                  75                  80  


Gly Ser Gly Cys Ala Leu Asp Ala Val Thr Arg Gly Leu Lys Thr Ala 
                85                  90                  95      


Leu Val Glu Arg Asp Asp Phe Ser Ser Gly Thr Ser Ser Arg Ser Thr 
            100                 105                 110         


Lys Leu Ile His Gly Gly Val Arg Tyr Leu Gln Lys Ala Ile Met Lys 
        115                 120                 125             


Leu Asp Ile Glu Gln Tyr Arg Met Val Lys Glu Ala Leu His Glu Arg 
    130                 135                 140                 


Ala Asn Leu Leu Glu Ile Ala Pro His Leu Ser Ala Pro Leu Pro Ile 
145                 150                 155                 160 


Met Leu Pro Val Tyr Lys Trp Trp Gln Leu Pro Tyr Tyr Trp Val Gly 
                165                 170                 175     


Ile Lys Leu Tyr Asp Leu Val Ala Gly Ser Asn Cys Leu Lys Ser Ser 
            180                 185                 190         


Tyr Val Leu Ser Lys Ser Arg Ala Leu Glu His Phe Pro Met Leu Gln 
        195                 200                 205             


Lys Asp Lys Leu Val Gly Ala Ile Val Tyr Tyr Asp Gly Gln His Asn 
    210                 215                 220                 


Asp Ala Arg Met Asn Leu Ala Ile Ala Leu Thr Ala Ala Arg Tyr Gly 
225                 230                 235                 240 


Ala Ala Thr Ala Asn Tyr Met Glu Val Val Ser Leu Leu Lys Lys Thr 
                245                 250                 255     


Asp Pro Gln Thr Gly Lys Val Arg Val Ser Gly Ala Arg Cys Lys Asp 
            260                 265                 270         


Val Leu Thr Gly Gln Glu Phe Asp Val Arg Ala Lys Cys Val Ile Asn 
        275                 280                 285             


Ala Thr Gly Pro Phe Thr Asp Ser Val Arg Lys Met Asp Asp Lys Asp 
    290                 295                 300                 


Ala Ala Ala Ile Cys Gln Pro Ser Ala Gly Val His Ile Val Met Pro 
305                 310                 315                 320 


Gly Tyr Tyr Ser Pro Glu Ser Met Gly Leu Leu Asp Pro Ala Thr Ser 
                325                 330                 335     


Asp Gly Arg Val Ile Phe Phe Leu Pro Trp Gln Lys Met Thr Ile Ala 
            340                 345                 350         


Gly Thr Thr Asp Thr Pro Thr Asp Val Thr His His Pro Ile Pro Ser 
        355                 360                 365             


Glu Glu Asp Ile Asn Phe Ile Leu Asn Glu Val Arg Asn Tyr Leu Ser 
    370                 375                 380                 


Cys Asp Val Glu Val Arg Arg Gly Asp Val Leu Ala Ala Trp Ser Gly 
385                 390                 395                 400 


Ile Arg Pro Leu Val Thr Asp Pro Lys Ser Ala Asp Thr Gln Ser Ile 
                405                 410                 415     


Ser Arg Asn His Val Val Asp Ile Ser Glu Ser Gly Leu Ile Thr Ile 
            420                 425                 430         


Ala Gly Gly Lys Trp Thr Thr Tyr Arg Ser Met Ala Glu Asp Thr Ile 
        435                 440                 445             


Asn Ala Ala Val Lys Thr His Asn Leu Lys Ala Gly Pro Ser Arg Thr 
    450                 455                 460                 


Val Gly Leu Phe Leu Gln Gly Gly Lys Asp Trp Ser Pro Thr Leu Tyr 
465                 470                 475                 480 


Ile Arg Leu Val Gln Asp Tyr Gly Leu Glu Ser Glu Val Ala Gln His 
                485                 490                 495     


Leu Ala Ala Thr Tyr Gly Asp Lys Ala Phe Glu Val Ala Lys Met Ala 
            500                 505                 510         


Ser Val Thr Gly Lys Arg Trp Pro Ile Val Gly Val Arg Leu Val Ser 
        515                 520                 525             


Glu Phe Pro Tyr Ile Glu Ala Glu Val Lys Tyr Gly Ile Lys Glu Tyr 
    530                 535                 540                 


Ala Cys Thr Ala Val Asp Met Ile Ser Arg Arg Thr Arg Leu Ala Phe 
545                 550                 555                 560 


Leu Asn Val Gln Ala Ala Glu Glu Ala Leu Pro Arg Ile Val Glu Leu 
                565                 570                 575     


Met Gly Arg Glu Leu Asn Trp Asp Asp Tyr Lys Lys Gln Glu Gln Leu 
            580                 585                 590         


Glu Thr Ala Arg Lys Phe Leu Tyr Tyr Glu Met Gly Tyr Lys Ser Arg 
        595                 600                 605             


Ser Glu Gln Leu Thr Asp Arg Ser Glu Ile Ser Leu Leu Pro Ser Asp 
    610                 615                 620                 


Ile Asp Arg Tyr Lys Lys Arg Phe His Lys Phe Asp Ala Asp Gln Lys 
625                 630                 635                 640 


Gly Phe Ile Thr Ile Val Asp Val Gln Arg Val Leu Glu Ser Ile Asn 
                645                 650                 655     


Val Gln Met Asp Glu Asn Thr Leu His Glu Ile Leu Asn Glu Val Asp 
            660                 665                 670         


Leu Asn Lys Asn Gly Gln Val Glu Leu Asn Glu Phe Leu Gln Leu Met 
        675                 680                 685             


Ser Ala Ile Gln Lys Gly Arg Val Ser Gly Ser Arg Leu Ala Ile Leu 
    690                 695                 700                 


Met Lys Thr Ala Glu Glu Asn Leu Asp Arg Arg Val Pro Ile Pro Val 
705                 710                 715                 720 


Asp Arg Ser Cys Gly Gly Leu 
                725         


<210>  4356
<211>  333
<212>  PRT
<213>  homo sapiens

<400>  4356

Met Pro Leu Gly Leu Gly Arg Arg Lys Lys Ala Pro Pro Leu Val Glu 
1               5                   10                  15      


Asn Glu Glu Ala Glu Pro Gly Arg Gly Gly Leu Gly Val Gly Glu Pro 
            20                  25                  30          


Gly Pro Leu Gly Gly Gly Gly Ser Gly Gly Pro Gln Met Gly Leu Pro 
        35                  40                  45              


Pro Pro Pro Pro Ala Leu Arg Pro Arg Leu Val Phe His Thr Gln Leu 
    50                  55                  60                  


Ala His Gly Ser Pro Thr Gly Arg Ile Glu Gly Phe Thr Asn Val Lys 
65                  70                  75                  80  


Glu Leu Tyr Gly Lys Ile Ala Glu Ala Phe Arg Leu Pro Thr Ala Glu 
                85                  90                  95      


Val Met Phe Cys Thr Leu Asn Thr His Lys Val Asp Met Asp Lys Leu 
            100                 105                 110         


Leu Gly Gly Gln Ile Gly Leu Glu Asp Phe Ile Phe Ala His Val Lys 
        115                 120                 125             


Gly Gln Arg Lys Glu Val Glu Val Phe Lys Ser Glu Asp Ala Leu Gly 
    130                 135                 140                 


Leu Thr Ile Thr Asp Asn Gly Ala Gly Tyr Ala Phe Ile Lys Arg Ile 
145                 150                 155                 160 


Lys Glu Gly Ser Val Ile Asp His Ile His Leu Ile Ser Val Gly Asp 
                165                 170                 175     


Met Ile Glu Ala Ile Asn Gly Gln Ser Leu Leu Gly Cys Arg His Tyr 
            180                 185                 190         


Glu Val Ala Arg Leu Leu Lys Glu Leu Pro Arg Gly Arg Thr Phe Thr 
        195                 200                 205             


Leu Lys Leu Thr Glu Pro Arg Lys Ala Phe Asp Met Ile Ser Gln Arg 
    210                 215                 220                 


Ser Ala Gly Gly Arg Pro Gly Ser Gly Pro Gln Leu Gly Thr Gly Arg 
225                 230                 235                 240 


Gly Thr Leu Arg Leu Arg Ser Arg Gly Pro Ala Thr Val Glu Asp Leu 
                245                 250                 255     


Pro Ser Ala Phe Glu Glu Lys Ala Ile Glu Lys Val Asp Asp Leu Leu 
            260                 265                 270         


Glu Ser Tyr Met Gly Ile Arg Asp Thr Glu Leu Ala Ala Thr Met Val 
        275                 280                 285             


Glu Leu Gly Lys Asp Lys Arg Asn Pro Asp Glu Leu Ala Glu Ala Leu 
    290                 295                 300                 


Asp Glu Arg Leu Gly Asp Phe Ala Phe Pro Asp Glu Phe Val Phe Asp 
305                 310                 315                 320 


Val Trp Gly Ala Ile Gly Asp Ala Lys Val Gly Arg Tyr 
                325                 330             


<210>  4357
<211>  395
<212>  PRT
<213>  homo sapiens

<400>  4357

Met Trp Ser Gly Leu Pro Ser Arg Gly Ser Thr Cys His Thr Thr Thr 
1               5                   10                  15      


Leu Pro Ala Leu Val Arg Thr Pro Thr Leu Met Met Gln Pro Ser Leu 
            20                  25                  30          


Asp Ile Lys Pro Phe Met Ser Phe Pro Val Asp Ser Ser Ser Ala Val 
        35                  40                  45              


Gly Leu Phe Pro Asn Phe Asn Thr Met Asp Pro Val Gln Lys Ala Val 
    50                  55                  60                  


Ile Asn His Thr Phe Gly Val Ser Ile Pro Pro Lys Lys Lys Gln Val 
65                  70                  75                  80  


Ile Ser Cys Asn Val Cys Gln Leu Arg Phe Asn Ser Asp Ser Gln Ala 
                85                  90                  95      


Glu Ala His Tyr Lys Gly Ser Lys His Ala Lys Lys Val Lys Ala Leu 
            100                 105                 110         


Asp Ala Thr Lys Asn Lys Pro Lys Met Val Pro Ser Lys Asp Ser Ala 
        115                 120                 125             


Lys Ala Asn Pro Ser Cys Ser Ile Thr Pro Ile Thr Gly Asn Asn Ser 
    130                 135                 140                 


Asp Lys Ser Glu Asp Lys Gly Lys Leu Lys Ala Ser Ser Ser Ser Gln 
145                 150                 155                 160 


Pro Ser Ser Ser Glu Ser Gly Ser Phe Leu Leu Lys Ser Gly Thr Thr 
                165                 170                 175     


Pro Leu Pro Pro Gly Ala Ala Thr Ser Pro Ser Lys Ser Thr Asn Gly 
            180                 185                 190         


Ala Pro Gly Thr Val Val Glu Ser Glu Glu Glu Lys Ala Lys Lys Leu 
        195                 200                 205             


Leu Tyr Cys Ser Leu Cys Lys Val Ala Val Asn Ser Leu Ser Gln Leu 
    210                 215                 220                 


Glu Ala His Asn Thr Gly Ser Lys His Lys Thr Met Val Glu Ala Arg 
225                 230                 235                 240 


Asn Gly Ala Gly Pro Ile Lys Ser Tyr Pro Arg Pro Gly Ser Arg Leu 
                245                 250                 255     


Lys Met Gln Asn Gly Ser Lys Gly Ser Gly Leu Gln Asn Lys Thr Phe 
            260                 265                 270         


His Cys Glu Ile Cys Asp Val His Val Asn Ser Glu Ile Gln Leu Lys 
        275                 280                 285             


Gln His Ile Ser Ser Arg Arg His Lys Asp Arg Val Ala Gly Lys Pro 
    290                 295                 300                 


Leu Lys Pro Lys Tyr Ser Pro Tyr Asn Lys Leu Gln Arg Ser Pro Ser 
305                 310                 315                 320 


Ile Leu Ala Ala Lys Leu Ala Phe Gln Lys Asp Met Met Lys Pro Leu 
                325                 330                 335     


Ala Pro Ala Phe Leu Ser Ser Pro Leu Ala Ala Ala Ala Ala Val Ser 
            340                 345                 350         


Ser Ala Leu Ser Leu Pro Pro Arg Pro Ser Ala Ser Leu Phe Gln Ala 
        355                 360                 365             


Pro Ala Ile Pro Pro Ala Leu Leu Arg Pro Gly His Gly Pro Ile Arg 
    370                 375                 380                 


Ala Thr Pro Ala Ser Ile Leu Phe Ala Pro Tyr 
385                 390                 395 


<210>  4358
<211>  1443
<212>  PRT
<213>  homo sapiens

<400>  4358

Met Tyr Ala Val Tyr Lys Gln Ala His Pro Pro Thr Gly Leu Glu Phe 
1               5                   10                  15      


Ser Met Tyr Cys Asn Phe Phe Asn Asn Ser Glu Arg Asn Leu Val Val 
            20                  25                  30          


Ala Gly Thr Ser Gln Leu Tyr Val Tyr Arg Leu Asn Arg Asp Ala Glu 
        35                  40                  45              


Ala Leu Thr Lys Asn Asp Arg Ser Thr Glu Gly Lys Ala His Arg Glu 
    50                  55                  60                  


Lys Leu Glu Leu Ala Ala Ser Phe Ser Phe Phe Gly Asn Val Met Ser 
65                  70                  75                  80  


Met Ala Ser Val Gln Leu Ala Gly Ala Lys Arg Asp Ala Leu Leu Leu 
                85                  90                  95      


Ser Phe Lys Asp Ala Lys Leu Ser Val Val Glu Tyr Asp Pro Gly Thr 
            100                 105                 110         


His Asp Leu Lys Thr Leu Ser Leu His Tyr Phe Glu Glu Pro Glu Leu 
        115                 120                 125             


Arg Asp Gly Phe Val Gln Asn Val His Thr Pro Arg Val Arg Val Asp 
    130                 135                 140                 


Pro Asp Gly Arg Cys Ala Ala Met Leu Val Tyr Gly Thr Arg Leu Val 
145                 150                 155                 160 


Val Leu Pro Phe Arg Arg Glu Ser Leu Ala Glu Glu His Glu Gly Leu 
                165                 170                 175     


Val Gly Glu Gly Gln Arg Ser Ser Phe Leu Pro Ser Tyr Ile Ile Asp 
            180                 185                 190         


Val Arg Ala Leu Asp Glu Lys Leu Leu Asn Ile Ile Asp Leu Gln Phe 
        195                 200                 205             


Leu His Gly Tyr Tyr Glu Pro Thr Leu Leu Ile Leu Phe Glu Pro Asn 
    210                 215                 220                 


Gln Thr Trp Pro Gly Arg Val Ala Val Arg Gln Asp Thr Cys Ser Ile 
225                 230                 235                 240 


Val Ala Ile Ser Leu Asn Ile Thr Gln Lys Val His Pro Val Ile Trp 
                245                 250                 255     


Ser Leu Thr Ser Leu Pro Phe Asp Cys Thr Gln Ala Leu Ala Val Pro 
            260                 265                 270         


Lys Pro Ile Gly Gly Val Val Val Phe Ala Val Asn Ser Leu Leu Tyr 
        275                 280                 285             


Leu Asn Gln Ser Val Pro Pro Tyr Gly Val Ala Leu Asn Ser Leu Thr 
    290                 295                 300                 


Thr Gly Thr Thr Ala Phe Pro Leu Arg Thr Gln Glu Gly Val Arg Ile 
305                 310                 315                 320 


Thr Leu Asp Cys Ala Gln Ala Thr Phe Ile Ser Tyr Asp Lys Met Val 
                325                 330                 335     


Ile Ser Leu Lys Gly Gly Glu Ile Tyr Val Leu Thr Leu Ile Thr Asp 
            340                 345                 350         


Gly Met Arg Ser Val Arg Ala Phe His Phe Asp Lys Ala Ala Ala Ser 
        355                 360                 365             


Val Leu Thr Thr Ser Met Val Thr Met Glu Pro Gly Tyr Leu Phe Leu 
    370                 375                 380                 


Gly Ser Arg Leu Gly Asn Ser Leu Leu Leu Lys Tyr Thr Glu Lys Leu 
385                 390                 395                 400 


Gln Glu Pro Pro Ala Ser Ala Val Arg Glu Ala Ala Asp Lys Glu Glu 
                405                 410                 415     


Pro Pro Ser Lys Lys Lys Arg Val Asp Ala Thr Ala Gly Trp Ser Ala 
            420                 425                 430         


Ala Gly Lys Ser Val Pro Gln Asp Glu Val Asp Glu Ile Glu Val Tyr 
        435                 440                 445             


Gly Ser Glu Ala Gln Ser Gly Thr Gln Leu Ala Thr Tyr Ser Phe Glu 
    450                 455                 460                 


Val Cys Asp Ser Ile Leu Asn Ile Gly Pro Cys Ala Asn Ala Ala Val 
465                 470                 475                 480 


Gly Glu Pro Ala Phe Leu Ser Glu Glu Phe Gln Asn Ser Pro Glu Pro 
                485                 490                 495     


Asp Leu Glu Ile Val Val Cys Ser Gly His Gly Lys Asn Gly Ala Leu 
            500                 505                 510         


Ser Val Leu Gln Lys Ser Ile Arg Pro Gln Val Val Thr Thr Phe Glu 
        515                 520                 525             


Leu Pro Gly Cys Tyr Asp Met Trp Thr Val Ile Ala Pro Val Arg Lys 
    530                 535                 540                 


Glu Glu Glu Asp Asn Pro Lys Gly Glu Gly Thr Glu Gln Glu Pro Ser 
545                 550                 555                 560 


Thr Thr Pro Glu Ala Asp Asp Asp Gly Arg Arg His Gly Phe Leu Ile 
                565                 570                 575     


Leu Ser Arg Glu Asp Ser Thr Met Ile Leu Gln Thr Gly Gln Glu Ile 
            580                 585                 590         


Met Glu Leu Asp Thr Ser Gly Phe Ala Thr Gln Gly Pro Thr Val Phe 
        595                 600                 605             


Ala Gly Asn Ile Gly Asp Asn Arg Tyr Ile Val Gln Val Ser Pro Leu 
    610                 615                 620                 


Gly Ile Arg Leu Leu Glu Gly Val Asn Gln Leu His Phe Ile Pro Val 
625                 630                 635                 640 


Asp Leu Gly Ala Pro Ile Val Gln Cys Ala Val Ala Asp Pro Tyr Val 
                645                 650                 655     


Val Ile Met Ser Ala Glu Gly His Val Thr Met Phe Leu Leu Lys Ser 
            660                 665                 670         


Asp Ser Tyr Gly Gly Arg His His Arg Leu Ala Leu His Lys Pro Pro 
        675                 680                 685             


Leu His His Gln Ser Lys Val Ile Thr Leu Cys Leu Tyr Arg Asp Leu 
    690                 695                 700                 


Ser Gly Met Phe Thr Thr Glu Ser Arg Leu Gly Gly Ala Arg Asp Glu 
705                 710                 715                 720 


Leu Gly Gly Arg Ser Gly Pro Glu Ala Glu Gly Leu Gly Ser Glu Thr 
                725                 730                 735     


Ser Pro Thr Val Asp Asp Glu Glu Glu Met Leu Tyr Gly Asp Ser Gly 
            740                 745                 750         


Ser Leu Phe Ser Pro Ser Lys Glu Glu Ala Arg Arg Ser Ser Gln Pro 
        755                 760                 765             


Pro Ala Asp Arg Asp Pro Ala Pro Phe Arg Ala Glu Pro Thr His Trp 
    770                 775                 780                 


Cys Leu Leu Val Arg Glu Asn Gly Thr Met Glu Ile Tyr Gln Leu Pro 
785                 790                 795                 800 


Asp Trp Arg Leu Val Phe Leu Val Lys Asn Phe Pro Val Gly Gln Arg 
                805                 810                 815     


Val Leu Val Asp Ser Ser Phe Gly Gln Pro Thr Thr Gln Gly Glu Ala 
            820                 825                 830         


Arg Arg Glu Glu Ala Thr Arg Gln Gly Glu Leu Pro Leu Val Lys Glu 
        835                 840                 845             


Val Leu Leu Val Ala Leu Gly Ser Arg Gln Ser Arg Pro Tyr Leu Leu 
    850                 855                 860                 


Val His Val Asp Gln Glu Leu Leu Ile Tyr Glu Ala Phe Pro His Asp 
865                 870                 875                 880 


Ser Gln Leu Gly Gln Gly Asn Leu Lys Val Arg Phe Lys Lys Val Pro 
                885                 890                 895     


His Asn Ile Asn Phe Arg Glu Lys Lys Pro Lys Pro Ser Lys Lys Lys 
            900                 905                 910         


Ala Glu Gly Gly Gly Ala Glu Glu Gly Ala Gly Ala Arg Gly Arg Val 
        915                 920                 925             


Ala Arg Phe Arg Tyr Phe Glu Asp Ile Tyr Gly Tyr Ser Gly Val Phe 
    930                 935                 940                 


Ile Cys Gly Pro Ser Pro His Trp Leu Leu Val Thr Gly Arg Gly Ala 
945                 950                 955                 960 


Leu Arg Leu His Pro Met Ala Ile Asp Gly Pro Val Asp Ser Phe Ala 
                965                 970                 975     


Pro Phe His Asn Val Asn Cys Pro Arg Gly Phe Leu Tyr Phe Asn Arg 
            980                 985                 990         


Gln Gly Glu Leu Arg Ile Ser Val  Leu Pro Ala Tyr Leu  Ser Tyr Asp 
        995                 1000                 1005             


Ala Pro  Trp Pro Val Arg Lys  Ile Pro Leu Arg Cys  Thr Ala His 
    1010                 1015                 1020             


Tyr Val  Ala Tyr His Val Glu  Ser Lys Val Tyr Ala  Val Ala Thr 
    1025                 1030                 1035             


Ser Thr  Asn Thr Pro Cys Ala  Arg Ile Pro Arg Met  Thr Gly Glu 
    1040                 1045                 1050             


Glu Lys  Glu Phe Glu Thr Ile  Glu Arg Asp Glu Arg  Tyr Ile His 
    1055                 1060                 1065             


Pro Gln  Gln Glu Ala Phe Ser  Ile Gln Leu Ile Ser  Pro Val Ser 
    1070                 1075                 1080             


Trp Glu  Ala Ile Pro Asn Ala  Arg Ile Glu Leu Gln  Glu Trp Glu 
    1085                 1090                 1095             


His Val  Thr Cys Met Lys Thr  Val Ser Leu Arg Ser  Glu Glu Thr 
    1100                 1105                 1110             


Val Ser  Gly Leu Lys Gly Tyr  Val Ala Ala Gly Thr  Cys Leu Met 
    1115                 1120                 1125             


Gln Gly  Glu Glu Val Thr Cys  Arg Gly Arg Ile Leu  Ile Met Asp 
    1130                 1135                 1140             


Val Ile  Glu Val Val Pro Glu  Pro Gly Gln Pro Leu  Thr Lys Asn 
    1145                 1150                 1155             


Lys Phe  Lys Val Leu Tyr Glu  Lys Glu Gln Lys Gly  Pro Val Thr 
    1160                 1165                 1170             


Ala Leu  Cys His Cys Asn Gly  His Leu Val Ser Ala  Ile Gly Gln 
    1175                 1180                 1185             


Lys Ile  Phe Leu Trp Ser Leu  Arg Ala Ser Glu Leu  Thr Gly Met 
    1190                 1195                 1200             


Ala Phe  Ile Asp Thr Gln Leu  Tyr Ile His Gln Met  Ile Ser Val 
    1205                 1210                 1215             


Lys Asn  Phe Ile Leu Ala Ala  Asp Val Met Lys Ser  Ile Ser Leu 
    1220                 1225                 1230             


Leu Arg  Tyr Gln Glu Glu Ser  Lys Thr Leu Ser Leu  Val Ser Arg 
    1235                 1240                 1245             


Asp Ala  Lys Pro Leu Glu Val  Tyr Ser Val Asp Phe  Met Val Asp 
    1250                 1255                 1260             


Asn Ala  Gln Leu Gly Phe Leu  Val Ser Asp Arg Asp  Arg Asn Leu 
    1265                 1270                 1275             


Met Val  Tyr Met Tyr Leu Pro  Glu Ala Lys Glu Ser  Phe Gly Gly 
    1280                 1285                 1290             


Met Arg  Leu Leu Arg Arg Ala  Asp Phe His Val Gly  Ala His Val 
    1295                 1300                 1305             


Asn Thr  Phe Trp Arg Thr Pro  Cys Arg Gly Ala Thr  Glu Gly Leu 
    1310                 1315                 1320             


Ser Lys  Lys Ser Val Val Trp  Glu Asn Lys His Ile  Thr Trp Phe 
    1325                 1330                 1335             


Ala Thr  Leu Asp Gly Gly Ile  Gly Leu Leu Leu Pro  Met Gln Glu 
    1340                 1345                 1350             


Lys Thr  Tyr Arg Arg Leu Leu  Met Leu Gln Asn Ala  Leu Thr Thr 
    1355                 1360                 1365             


Met Leu  Pro His His Ala Gly  Leu Asn Pro Arg Ala  Phe Arg Met 
    1370                 1375                 1380             


Leu His  Val Asp Arg Arg Thr  Leu Gln Asn Ala Val  Arg Asn Val 
    1385                 1390                 1395             


Leu Asp  Gly Glu Leu Leu Asn  Arg Tyr Leu Tyr Leu  Ser Thr Met 
    1400                 1405                 1410             


Glu Arg  Ser Glu Leu Ala Lys  Lys Ile Gly Thr Thr  Pro Asp Ile 
    1415                 1420                 1425             


Ile Leu  Asp Asp Leu Leu Glu  Thr Asp Arg Val Thr  Ala His Phe 
    1430                 1435                 1440             


<210>  4359
<211>  141
<212>  PRT
<213>  homo sapiens

<400>  4359

Met Pro Pro Phe Gly Tyr Lys Thr Glu Thr Ser Thr Ala Val Glu Lys 
1               5                   10                  15      


Lys Glu Lys Pro Leu Pro Arg Leu Asn Ile His Ser Gly Phe Trp Ile 
            20                  25                  30          


Leu Ala Ser Ile Val Val Thr Tyr Tyr Val Asp Phe Phe Lys Thr Leu 
        35                  40                  45              


Lys Glu Asn Phe His Thr Ser Ser Trp Phe Leu Cys Gly Ser Ala Leu 
    50                  55                  60                  


Leu Leu Val Ser Leu Ser Ile Ala Phe Tyr Cys Ile Val Tyr Leu Glu 
65                  70                  75                  80  


Trp Tyr Cys Gly Ile Gly Glu Tyr Asp Val Lys Tyr Pro Ala Leu Ile 
                85                  90                  95      


Pro Ile Thr Thr Ala Ser Phe Ile Ala Ala Gly Ile Cys Phe Asn Ile 
            100                 105                 110         


Ala Leu Trp His Val Trp Ser Phe Phe Thr Pro Leu Leu Leu Phe Thr 
        115                 120                 125             


Gln Phe Met Gly Val Val Met Phe Ile Thr Leu Leu Gly 
    130                 135                 140     


<210>  4360
<211>  475
<212>  PRT
<213>  homo sapiens

<400>  4360

Met Ser Asp Phe Asp Glu Phe Glu Arg Gln Leu Asn Glu Asn Lys Gln 
1               5                   10                  15      


Glu Arg Asp Lys Glu Asn Arg His Arg Lys Arg Ser His Ser Arg Ser 
            20                  25                  30          


Arg Ser Arg Asp Arg Lys Arg Arg Ser Arg Ser Arg Asp Arg Arg Asn 
        35                  40                  45              


Arg Asp Gln Arg Ser Ala Ser Arg Asp Arg Arg Arg Arg Ser Lys Pro 
    50                  55                  60                  


Leu Thr Arg Gly Ala Lys Glu Glu His Gly Gly Leu Ile Arg Ser Pro 
65                  70                  75                  80  


Arg His Glu Lys Lys Lys Lys Val Arg Lys Tyr Trp Asp Val Pro Pro 
                85                  90                  95      


Pro Gly Phe Glu His Ile Thr Pro Met Gln Tyr Lys Ala Met Gln Ala 
            100                 105                 110         


Ala Gly Gln Ile Pro Ala Thr Ala Leu Leu Pro Thr Met Thr Pro Asp 
        115                 120                 125             


Gly Leu Ala Val Thr Pro Thr Pro Val Pro Val Val Gly Ser Gln Met 
    130                 135                 140                 


Thr Arg Gln Ala Arg Arg Leu Tyr Val Gly Asn Ile Pro Phe Gly Ile 
145                 150                 155                 160 


Thr Glu Glu Ala Met Met Asp Phe Phe Asn Ala Gln Met Arg Leu Gly 
                165                 170                 175     


Gly Leu Thr Gln Ala Pro Gly Asn Pro Val Leu Ala Val Gln Ile Asn 
            180                 185                 190         


Gln Asp Lys Asn Phe Ala Phe Leu Glu Phe Arg Ser Val Asp Glu Thr 
        195                 200                 205             


Thr Gln Ala Met Ala Phe Asp Gly Ile Ile Phe Gln Gly Gln Ser Leu 
    210                 215                 220                 


Lys Ile Arg Arg Pro His Asp Tyr Gln Pro Leu Pro Gly Met Ser Glu 
225                 230                 235                 240 


Asn Pro Ser Val Tyr Val Pro Gly Val Val Ser Thr Val Val Pro Asp 
                245                 250                 255     


Ser Ala His Lys Leu Phe Ile Gly Gly Leu Pro Asn Tyr Leu Asn Asp 
            260                 265                 270         


Asp Gln Val Lys Glu Leu Leu Thr Ser Phe Gly Pro Leu Lys Ala Phe 
        275                 280                 285             


Asn Leu Val Lys Asp Ser Ala Thr Gly Leu Ser Lys Gly Tyr Ala Phe 
    290                 295                 300                 


Cys Glu Tyr Val Asp Ile Asn Val Thr Asp Gln Ala Ile Ala Gly Leu 
305                 310                 315                 320 


Asn Gly Met Gln Leu Gly Asp Lys Lys Leu Leu Val Gln Arg Ala Ser 
                325                 330                 335     


Val Gly Ala Lys Asn Ala Thr Leu Val Ser Pro Pro Ser Thr Ile Asn 
            340                 345                 350         


Gln Thr Pro Val Thr Leu Gln Val Pro Gly Leu Met Ser Ser Gln Val 
        355                 360                 365             


Gln Met Gly Gly His Pro Thr Glu Val Leu Cys Leu Met Asn Met Val 
    370                 375                 380                 


Leu Pro Glu Glu Leu Leu Asp Asp Glu Glu Tyr Glu Glu Ile Val Glu 
385                 390                 395                 400 


Asp Val Arg Asp Glu Cys Ser Lys Tyr Gly Leu Val Lys Ser Ile Glu 
                405                 410                 415     


Ile Pro Arg Pro Val Asp Gly Val Glu Val Pro Gly Cys Gly Lys Ile 
            420                 425                 430         


Phe Val Glu Phe Thr Ser Val Phe Asp Cys Gln Lys Ala Met Gln Gly 
        435                 440                 445             


Leu Thr Gly Arg Lys Phe Ala Asn Arg Val Val Val Thr Lys Tyr Cys 
    450                 455                 460                 


Asp Pro Asp Ser Tyr His Arg Arg Asp Phe Trp 
465                 470                 475 


<210>  4361
<211>  61
<212>  PRT
<213>  homo sapiens

<400>  4361

Met Asp Pro Asn Cys Ser Cys Ala Ala Gly Asp Ser Cys Thr Cys Ala 
1               5                   10                  15      


Gly Ser Cys Lys Cys Lys Glu Cys Lys Cys Thr Ser Cys Lys Lys Ser 
            20                  25                  30          


Cys Cys Ser Cys Cys Pro Val Gly Cys Ala Lys Cys Ala Gln Gly Cys 
        35                  40                  45              


Ile Cys Lys Gly Ala Ser Asp Lys Cys Ser Cys Cys Ala 
    50                  55                  60      


<210>  4362
<211>  460
<212>  PRT
<213>  homo sapiens

<400>  4362

Met Phe Leu Ala Thr Leu Tyr Phe Ala Leu Pro Leu Leu Asp Leu Leu 
1               5                   10                  15      


Leu Ser Ala Glu Val Ser Gly Gly Asp Arg Leu Asp Cys Val Lys Ala 
            20                  25                  30          


Ser Asp Gln Cys Leu Lys Glu Gln Ser Cys Ser Thr Lys Tyr Arg Thr 
        35                  40                  45              


Leu Arg Gln Cys Val Ala Gly Lys Glu Thr Asn Phe Ser Leu Ala Ser 
    50                  55                  60                  


Gly Leu Glu Ala Lys Asp Glu Cys Arg Ser Ala Met Glu Ala Leu Lys 
65                  70                  75                  80  


Gln Lys Ser Leu Tyr Asn Cys Arg Cys Lys Arg Gly Met Lys Lys Glu 
                85                  90                  95      


Lys Asn Cys Leu Arg Ile Tyr Trp Ser Met Tyr Gln Ser Leu Gln Gly 
            100                 105                 110         


Asn Asp Leu Leu Glu Asp Ser Pro Tyr Glu Pro Val Asn Ser Arg Leu 
        115                 120                 125             


Ser Asp Ile Phe Arg Val Val Pro Phe Ile Ser Val Glu His Ile Pro 
    130                 135                 140                 


Lys Gly Asn Asn Cys Leu Asp Ala Ala Lys Ala Cys Asn Leu Asp Asp 
145                 150                 155                 160 


Ile Cys Lys Lys Tyr Arg Ser Ala Tyr Ile Thr Pro Cys Thr Thr Ser 
                165                 170                 175     


Val Ser Asn Asp Val Cys Asn Arg Arg Lys Cys His Lys Ala Leu Arg 
            180                 185                 190         


Gln Phe Phe Asp Lys Val Pro Ala Lys His Ser Tyr Gly Met Leu Phe 
        195                 200                 205             


Cys Ser Cys Arg Asp Ile Ala Cys Thr Glu Arg Arg Arg Gln Thr Ile 
    210                 215                 220                 


Val Pro Val Cys Ser Tyr Glu Glu Arg Glu Lys Pro Asn Cys Leu Asn 
225                 230                 235                 240 


Leu Gln Asp Ser Cys Lys Thr Asn Tyr Ile Cys Arg Ser Arg Leu Ala 
                245                 250                 255     


Asp Phe Phe Thr Asn Cys Gln Pro Glu Ser Arg Ser Val Ser Ser Cys 
            260                 265                 270         


Leu Lys Glu Asn Tyr Ala Asp Cys Leu Leu Ala Tyr Ser Gly Leu Ile 
        275                 280                 285             


Gly Thr Val Met Thr Pro Asn Tyr Ile Asp Ser Ser Ser Leu Ser Val 
    290                 295                 300                 


Ala Pro Trp Cys Asp Cys Ser Asn Ser Gly Asn Asp Leu Glu Glu Cys 
305                 310                 315                 320 


Leu Lys Phe Leu Asn Phe Phe Lys Asp Asn Thr Cys Leu Lys Asn Ala 
                325                 330                 335     


Ile Gln Ala Phe Gly Asn Gly Ser Asp Val Thr Val Trp Gln Pro Ala 
            340                 345                 350         


Phe Pro Val Gln Thr Thr Thr Ala Thr Thr Thr Thr Ala Leu Arg Val 
        355                 360                 365             


Lys Asn Lys Pro Leu Gly Pro Ala Gly Ser Glu Asn Glu Ile Pro Thr 
    370                 375                 380                 


His Val Leu Pro Pro Cys Ala Asn Leu Gln Ala Gln Lys Leu Lys Ser 
385                 390                 395                 400 


Asn Val Ser Gly Asn Thr His Leu Cys Ile Ser Asn Gly Asn Tyr Glu 
                405                 410                 415     


Lys Glu Gly Leu Gly Ala Ser Ser His Ile Thr Thr Lys Ser Met Ala 
            420                 425                 430         


Ala Pro Pro Ser Cys Gly Leu Ser Pro Leu Leu Val Leu Val Val Thr 
        435                 440                 445             


Ala Leu Ser Thr Leu Leu Ser Leu Thr Glu Thr Ser 
    450                 455                 460 


<210>  4363
<211>  795
<212>  PRT
<213>  homo sapiens

<400>  4363

Met Ser Ala Arg Thr Pro Leu Pro Thr Val Asn Glu Arg Asp Thr Glu 
1               5                   10                  15      


Asn His Thr Ser Val Asp Gly Tyr Thr Glu Pro His Ile Gln Pro Thr 
            20                  25                  30          


Lys Ser Ser Ser Arg Gln Asn Ile Pro Arg Cys Arg Asn Ser Ile Thr 
        35                  40                  45              


Ser Ala Thr Asp Glu Gln Pro His Ile Gly Asn Tyr Arg Leu Gln Lys 
    50                  55                  60                  


Thr Ile Gly Lys Gly Asn Phe Ala Lys Val Lys Leu Ala Arg His Val 
65                  70                  75                  80  


Leu Thr Gly Arg Glu Val Ala Val Lys Ile Ile Asp Lys Thr Gln Leu 
                85                  90                  95      


Asn Pro Thr Ser Leu Gln Lys Leu Phe Arg Glu Val Arg Ile Met Lys 
            100                 105                 110         


Ile Leu Asn His Pro Asn Ile Val Lys Leu Phe Glu Val Ile Glu Thr 
        115                 120                 125             


Glu Lys Thr Leu Tyr Leu Val Met Glu Tyr Ala Ser Gly Gly Glu Val 
    130                 135                 140                 


Phe Asp Tyr Leu Val Ala His Gly Arg Met Lys Glu Lys Glu Ala Arg 
145                 150                 155                 160 


Ala Lys Phe Arg Gln Ile Val Ser Ala Val Gln Tyr Cys His Gln Lys 
                165                 170                 175     


Tyr Ile Val His Arg Asp Leu Lys Ala Glu Asn Leu Leu Leu Asp Gly 
            180                 185                 190         


Asp Met Asn Ile Lys Ile Ala Asp Phe Gly Phe Ser Asn Glu Phe Thr 
        195                 200                 205             


Val Gly Asn Lys Leu Asp Thr Phe Cys Gly Ser Pro Pro Tyr Ala Ala 
    210                 215                 220                 


Pro Glu Leu Phe Gln Gly Lys Lys Tyr Asp Gly Pro Glu Val Asp Val 
225                 230                 235                 240 


Trp Ser Leu Gly Val Ile Leu Tyr Thr Leu Val Ser Gly Ser Leu Pro 
                245                 250                 255     


Phe Asp Gly Gln Asn Leu Lys Glu Leu Arg Glu Arg Val Leu Arg Gly 
            260                 265                 270         


Lys Tyr Arg Ile Pro Phe Tyr Met Ser Thr Asp Cys Glu Asn Leu Leu 
        275                 280                 285             


Lys Lys Leu Leu Val Leu Asn Pro Ile Lys Arg Gly Ser Leu Glu Gln 
    290                 295                 300                 


Ile Met Lys Asp Arg Trp Met Asn Val Gly His Glu Glu Glu Glu Leu 
305                 310                 315                 320 


Lys Pro Tyr Thr Glu Pro Asp Pro Asp Phe Asn Asp Thr Lys Arg Ile 
                325                 330                 335     


Asp Ile Met Val Thr Met Gly Phe Ala Arg Asp Glu Ile Asn Asp Ala 
            340                 345                 350         


Leu Ile Asn Gln Lys Tyr Asp Glu Val Met Ala Thr Tyr Ile Leu Leu 
        355                 360                 365             


Gly Arg Lys Pro Pro Glu Phe Glu Gly Gly Glu Ser Leu Ser Ser Gly 
    370                 375                 380                 


Asn Leu Cys Gln Arg Ser Arg Pro Ser Ser Asp Leu Asn Asn Ser Thr 
385                 390                 395                 400 


Leu Gln Ser Pro Ala His Leu Lys Val Gln Arg Ser Ile Ser Ala Asn 
                405                 410                 415     


Gln Lys Gln Arg Arg Phe Ser Asp His Ala Gly Pro Ser Ile Pro Pro 
            420                 425                 430         


Ala Val Ser Tyr Thr Lys Arg Pro Gln Ala Asn Ser Val Glu Ser Glu 
        435                 440                 445             


Gln Lys Glu Glu Trp Asp Lys Asp Val Ala Arg Lys Leu Gly Ser Thr 
    450                 455                 460                 


Thr Val Gly Ser Lys Ser Glu Met Thr Ala Ser Pro Leu Val Gly Pro 
465                 470                 475                 480 


Glu Arg Lys Lys Ser Ser Thr Ile Pro Ser Asn Asn Val Tyr Ser Gly 
                485                 490                 495     


Gly Ser Met Ala Arg Arg Asn Thr Tyr Val Cys Glu Arg Thr Thr Asp 
            500                 505                 510         


Arg Tyr Val Ala Leu Gln Asn Gly Lys Asp Ser Ser Leu Thr Glu Met 
        515                 520                 525             


Ser Val Ser Ser Ile Ser Ser Ala Gly Ser Ser Val Ala Ser Ala Val 
    530                 535                 540                 


Pro Ser Ala Arg Pro Arg His Gln Lys Ser Met Ser Thr Ser Gly His 
545                 550                 555                 560 


Pro Ile Lys Val Thr Leu Pro Thr Ile Lys Asp Gly Ser Glu Ala Tyr 
                565                 570                 575     


Arg Pro Gly Thr Thr Gln Arg Val Pro Ala Ala Ser Pro Ser Ala His 
            580                 585                 590         


Ser Ile Ser Thr Ala Thr Pro Asp Arg Thr Arg Phe Pro Arg Gly Ser 
        595                 600                 605             


Ser Ser Arg Ser Thr Phe His Gly Glu Gln Leu Arg Glu Arg Arg Ser 
    610                 615                 620                 


Val Ala Tyr Asn Gly Pro Pro Ala Ser Pro Ser His Glu Thr Gly Ala 
625                 630                 635                 640 


Phe Ala His Ala Arg Arg Gly Thr Ser Thr Gly Ile Ile Ser Lys Ile 
                645                 650                 655     


Thr Ser Lys Phe Val Arg Arg Asp Pro Ser Glu Gly Glu Ala Ser Gly 
            660                 665                 670         


Arg Thr Asp Thr Ser Arg Ser Thr Ser Gly Glu Pro Lys Glu Arg Asp 
        675                 680                 685             


Lys Glu Glu Gly Lys Asp Ser Lys Pro Arg Ser Leu Arg Phe Thr Trp 
    690                 695                 700                 


Ser Met Lys Thr Thr Ser Ser Met Asp Pro Asn Asp Met Met Arg Glu 
705                 710                 715                 720 


Ile Arg Lys Val Leu Asp Ala Asn Asn Cys Asp Tyr Glu Gln Lys Glu 
                725                 730                 735     


Arg Phe Leu Leu Phe Cys Val His Gly Asp Ala Arg Gln Asp Ser Leu 
            740                 745                 750         


Val Gln Trp Glu Met Glu Val Cys Lys Leu Pro Arg Leu Ser Leu Asn 
        755                 760                 765             


Gly Val Arg Phe Lys Arg Ile Ser Gly Thr Ser Ile Ala Phe Lys Asn 
    770                 775                 780                 


Ile Ala Ser Lys Ile Ala Asn Glu Leu Lys Leu 
785                 790                 795 


<210>  4364
<211>  365
<212>  PRT
<213>  homo sapiens

<400>  4364

Met Asn Ile Met Asp Phe Asn Val Lys Lys Leu Ala Ala Asp Ala Gly 
1               5                   10                  15      


Thr Phe Leu Ser Arg Ala Val Gln Phe Thr Glu Glu Lys Leu Gly Gln 
            20                  25                  30          


Ala Glu Lys Thr Glu Leu Asp Ala His Leu Glu Asn Leu Leu Ser Lys 
        35                  40                  45              


Ala Glu Cys Thr Lys Ile Trp Thr Glu Lys Ile Met Lys Gln Thr Glu 
    50                  55                  60                  


Val Leu Leu Gln Pro Asn Pro Asn Ala Arg Ile Glu Glu Phe Val Tyr 
65                  70                  75                  80  


Glu Lys Leu Asp Arg Lys Ala Pro Ser Arg Ile Asn Asn Pro Glu Leu 
                85                  90                  95      


Leu Gly Gln Tyr Met Ile Asp Ala Gly Thr Glu Phe Gly Pro Gly Thr 
            100                 105                 110         


Ala Tyr Gly Asn Ala Leu Ile Lys Cys Gly Glu Thr Gln Lys Arg Ile 
        115                 120                 125             


Gly Thr Ala Asp Arg Glu Leu Ile Gln Thr Ser Ala Leu Asn Phe Leu 
    130                 135                 140                 


Thr Pro Leu Arg Asn Phe Ile Glu Gly Asp Tyr Lys Thr Ile Ala Lys 
145                 150                 155                 160 


Glu Arg Lys Leu Leu Gln Asn Lys Arg Leu Asp Leu Asp Ala Ala Lys 
                165                 170                 175     


Thr Arg Leu Lys Lys Ala Lys Ala Ala Glu Thr Arg Asn Ser Ser Glu 
            180                 185                 190         


Gln Glu Leu Arg Ile Thr Gln Ser Glu Phe Asp Arg Gln Ala Glu Ile 
        195                 200                 205             


Thr Arg Leu Leu Leu Glu Gly Ile Ser Ser Thr His Ala His His Leu 
    210                 215                 220                 


Arg Cys Leu Asn Asp Phe Val Glu Ala Gln Met Thr Tyr Tyr Ala Gln 
225                 230                 235                 240 


Cys Tyr Gln Tyr Met Leu Asp Leu Gln Lys Gln Leu Gly Ser Phe Pro 
                245                 250                 255     


Ser Asn Tyr Leu Ser Asn Asn Asn Gln Thr Ser Val Thr Pro Val Pro 
            260                 265                 270         


Ser Val Leu Pro Asn Ala Ile Gly Ser Ser Ala Met Ala Ser Thr Ser 
        275                 280                 285             


Gly Leu Val Ile Thr Ser Pro Ser Asn Leu Ser Asp Leu Lys Glu Cys 
    290                 295                 300                 


Ser Gly Ser Arg Lys Ala Arg Val Leu Tyr Asp Tyr Asp Ala Ala Asn 
305                 310                 315                 320 


Ser Thr Glu Leu Ser Leu Leu Ala Asp Glu Val Ile Thr Val Phe Ser 
                325                 330                 335     


Val Val Gly Met Asp Ser Asp Trp Leu Met Gly Glu Arg Gly Asn Gln 
            340                 345                 350         


Lys Gly Lys Val Pro Ile Thr Tyr Leu Glu Leu Leu Asn 
        355                 360                 365 


<210>  4365
<211>  437
<212>  PRT
<213>  homo sapiens

<400>  4365

Met Ala Leu Ala Gly Ala Pro Ala Gly Gly Pro Cys Ala Pro Ala Leu 
1               5                   10                  15      


Glu Ala Leu Leu Gly Ala Gly Ala Leu Arg Leu Leu Asp Ser Ser Gln 
            20                  25                  30          


Ile Val Ile Ile Ser Ala Ala Gln Asp Ala Ser Ala Pro Pro Ala Pro 
        35                  40                  45              


Thr Gly Pro Ala Ala Pro Ala Ala Gly Pro Cys Asp Pro Asp Leu Leu 
    50                  55                  60                  


Leu Phe Ala Thr Pro Gln Ala Pro Arg Pro Thr Pro Ser Ala Pro Arg 
65                  70                  75                  80  


Pro Ala Leu Gly Arg Pro Pro Val Lys Arg Arg Leu Asp Leu Glu Thr 
                85                  90                  95      


Asp His Gln Tyr Leu Ala Glu Ser Ser Gly Pro Ala Arg Gly Arg Gly 
            100                 105                 110         


Arg His Pro Gly Lys Gly Val Lys Ser Pro Gly Glu Lys Ser Arg Tyr 
        115                 120                 125             


Glu Thr Ser Leu Asn Leu Thr Thr Lys Arg Phe Leu Glu Leu Leu Ser 
    130                 135                 140                 


His Ser Ala Asp Gly Val Val Asp Leu Asn Trp Ala Ala Glu Val Leu 
145                 150                 155                 160 


Lys Val Gln Lys Arg Arg Ile Tyr Asp Ile Thr Asn Val Leu Glu Gly 
                165                 170                 175     


Ile Gln Leu Ile Ala Lys Lys Ser Lys Asn His Ile Gln Trp Leu Gly 
            180                 185                 190         


Ser His Thr Thr Val Gly Val Gly Gly Arg Leu Glu Gly Leu Thr Gln 
        195                 200                 205             


Asp Leu Arg Gln Leu Gln Glu Ser Glu Gln Gln Leu Asp His Leu Met 
    210                 215                 220                 


Asn Ile Cys Thr Thr Gln Leu Arg Leu Leu Ser Glu Asp Thr Asp Ser 
225                 230                 235                 240 


Gln Arg Leu Ala Tyr Val Thr Cys Gln Asp Leu Arg Ser Ile Ala Asp 
                245                 250                 255     


Pro Ala Glu Gln Met Val Met Val Ile Lys Ala Pro Pro Glu Thr Gln 
            260                 265                 270         


Leu Gln Ala Val Asp Ser Ser Glu Asn Phe Gln Ile Ser Leu Lys Ser 
        275                 280                 285             


Lys Gln Gly Pro Ile Asp Val Phe Leu Cys Pro Glu Glu Thr Val Gly 
    290                 295                 300                 


Gly Ile Ser Pro Gly Lys Thr Pro Ser Gln Glu Val Thr Ser Glu Glu 
305                 310                 315                 320 


Glu Asn Arg Ala Thr Asp Ser Ala Thr Ile Val Ser Pro Pro Pro Ser 
                325                 330                 335     


Ser Pro Pro Ser Ser Leu Thr Thr Asp Pro Ser Gln Ser Leu Leu Ser 
            340                 345                 350         


Leu Glu Gln Glu Pro Leu Leu Ser Arg Met Gly Ser Leu Arg Ala Pro 
        355                 360                 365             


Val Asp Glu Asp Arg Leu Ser Pro Leu Val Ala Ala Asp Ser Leu Leu 
    370                 375                 380                 


Glu His Val Arg Glu Asp Phe Ser Gly Leu Leu Pro Glu Glu Phe Ile 
385                 390                 395                 400 


Ser Leu Ser Pro Pro His Glu Ala Leu Asp Tyr His Phe Gly Leu Glu 
                405                 410                 415     


Glu Gly Glu Gly Ile Arg Asp Leu Phe Asp Cys Asp Phe Gly Asp Leu 
            420                 425                 430         


Thr Pro Leu Asp Phe 
        435         


<210>  4366
<211>  686
<212>  PRT
<213>  homo sapiens

<400>  4366

Met Gln Leu Gly Glu Gln Leu Leu Val Ser Ser Val Asn Leu Pro Gly 
1               5                   10                  15      


Ala His Phe Tyr Pro Leu Glu Ser Ala Arg Gly Gly Ser Gly Gly Ser 
            20                  25                  30          


Ala Gly His Leu Pro Ser Ala Ala Pro Ser Pro Gln Lys Leu Asp Leu 
        35                  40                  45              


Asp Lys Ala Ser Lys Lys Phe Ser Gly Ser Leu Ser Cys Glu Ala Val 
    50                  55                  60                  


Ser Gly Glu Pro Ala Ala Ala Ser Ala Gly Ala Pro Ala Ala Met Leu 
65                  70                  75                  80  


Ser Asp Thr Asp Ala Gly Asp Ala Phe Ala Ser Ala Ala Ala Val Ala 
                85                  90                  95      


Lys Pro Gly Pro Pro Asp Gly Arg Lys Gly Ser Pro Cys Gly Glu Glu 
            100                 105                 110         


Glu Leu Pro Ser Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala 
        115                 120                 125             


Ala Ala Thr Ala Arg Tyr Ser Met Asp Ser Leu Ser Ser Glu Arg Tyr 
    130                 135                 140                 


Tyr Leu Gln Ser Pro Gly Pro Gln Gly Ser Glu Leu Ala Ala Pro Cys 
145                 150                 155                 160 


Ser Leu Phe Pro Tyr Gln Ala Ala Ala Gly Ala Pro His Gly Pro Val 
                165                 170                 175     


Tyr Pro Ala Pro Asn Gly Ala Arg Tyr Pro Tyr Gly Ser Met Leu Pro 
            180                 185                 190         


Pro Gly Gly Phe Pro Ala Ala Val Cys Pro Pro Gly Arg Ala Gln Phe 
        195                 200                 205             


Gly Pro Gly Ala Gly Ala Gly Ser Gly Ala Gly Gly Ser Ser Gly Gly 
    210                 215                 220                 


Gly Gly Gly Pro Gly Thr Tyr Gln Tyr Ser Gln Gly Ala Pro Leu Tyr 
225                 230                 235                 240 


Gly Pro Tyr Pro Gly Ala Ala Ala Ala Gly Ser Cys Gly Gly Leu Gly 
                245                 250                 255     


Gly Leu Gly Val Pro Gly Ser Gly Phe Arg Ala His Val Tyr Leu Cys 
            260                 265                 270         


Asn Arg Pro Leu Trp Leu Lys Phe His Arg His Gln Thr Glu Met Ile 
        275                 280                 285             


Ile Thr Lys Gln Gly Arg Arg Met Phe Pro Phe Leu Ser Phe Asn Ile 
    290                 295                 300                 


Asn Gly Leu Asn Pro Thr Ala His Tyr Asn Val Phe Val Glu Val Val 
305                 310                 315                 320 


Leu Ala Asp Pro Asn His Trp Arg Phe Gln Gly Gly Lys Trp Val Thr 
                325                 330                 335     


Cys Gly Lys Ala Asp Asn Asn Met Gln Gly Asn Lys Met Tyr Val His 
            340                 345                 350         


Pro Glu Ser Pro Asn Thr Gly Ser His Trp Met Arg Gln Glu Ile Ser 
        355                 360                 365             


Phe Gly Lys Leu Lys Leu Thr Asn Asn Lys Gly Ala Asn Asn Asn Asn 
    370                 375                 380                 


Thr Gln Met Ile Val Leu Gln Ser Leu His Lys Tyr Gln Pro Arg Leu 
385                 390                 395                 400 


His Ile Val Glu Val Thr Glu Asp Gly Val Glu Asp Leu Asn Glu Pro 
                405                 410                 415     


Ser Lys Thr Gln Thr Phe Thr Phe Ser Glu Thr Gln Phe Ile Ala Val 
            420                 425                 430         


Thr Ala Tyr Gln Asn Thr Asp Ile Thr Gln Leu Lys Ile Asp His Asn 
        435                 440                 445             


Pro Phe Ala Lys Gly Phe Arg Asp Asn Tyr Asp Ser Ser His Gln Ile 
    450                 455                 460                 


Val Pro Gly Gly Arg Tyr Gly Val Gln Ser Phe Phe Pro Glu Pro Phe 
465                 470                 475                 480 


Val Asn Thr Leu Pro Gln Ala Arg Tyr Tyr Asn Gly Glu Arg Thr Val 
                485                 490                 495     


Pro Gln Thr Asn Gly Leu Leu Ser Pro Gln Gln Ser Glu Glu Val Ala 
            500                 505                 510         


Asn Pro Pro Gln Arg Trp Leu Val Thr Pro Val Gln Gln Pro Gly Thr 
        515                 520                 525             


Asn Lys Leu Asp Ile Ser Ser Tyr Glu Ser Glu Tyr Thr Ser Ser Thr 
    530                 535                 540                 


Leu Leu Pro Tyr Gly Ile Lys Ser Leu Pro Leu Gln Thr Ser His Ala 
545                 550                 555                 560 


Leu Gly Tyr Tyr Pro Asp Pro Thr Phe Pro Ala Met Ala Gly Trp Gly 
                565                 570                 575     


Gly Arg Gly Ser Tyr Gln Arg Lys Met Ala Ala Gly Leu Pro Trp Thr 
            580                 585                 590         


Ser Arg Thr Ser Pro Thr Val Phe Ser Glu Asp Gln Leu Ser Lys Glu 
        595                 600                 605             


Lys Val Lys Glu Glu Ile Gly Ser Ser Trp Ile Glu Thr Pro Pro Ser 
    610                 615                 620                 


Ile Lys Ser Leu Asp Ser Asn Asp Ser Gly Val Tyr Thr Ser Ala Cys 
625                 630                 635                 640 


Lys Arg Arg Arg Leu Ser Pro Ser Asn Ser Ser Asn Glu Asn Ser Pro 
                645                 650                 655     


Ser Ile Lys Cys Glu Asp Ile Asn Ala Glu Glu Tyr Ser Lys Asp Thr 
            660                 665                 670         


Ser Lys Gly Met Gly Gly Tyr Tyr Ala Phe Tyr Thr Thr Pro 
        675                 680                 685     


<210>  4367
<211>  2414
<212>  PRT
<213>  homo sapiens

<400>  4367

Met Ala Glu Asn Val Val Glu Pro Gly Pro Pro Ser Ala Lys Arg Pro 
1               5                   10                  15      


Lys Leu Ser Ser Pro Ala Leu Ser Ala Ser Ala Ser Asp Gly Thr Asp 
            20                  25                  30          


Phe Gly Ser Leu Phe Asp Leu Glu His Asp Leu Pro Asp Glu Leu Ile 
        35                  40                  45              


Asn Ser Thr Glu Leu Gly Leu Thr Asn Gly Gly Asp Ile Asn Gln Leu 
    50                  55                  60                  


Gln Thr Ser Leu Gly Met Val Gln Asp Ala Ala Ser Lys His Lys Gln 
65                  70                  75                  80  


Leu Ser Glu Leu Leu Arg Ser Gly Ser Ser Pro Asn Leu Asn Met Gly 
                85                  90                  95      


Val Gly Gly Pro Gly Gln Val Met Ala Ser Gln Ala Gln Gln Ser Ser 
            100                 105                 110         


Pro Gly Leu Gly Leu Ile Asn Ser Met Val Lys Ser Pro Met Thr Gln 
        115                 120                 125             


Ala Gly Leu Thr Ser Pro Asn Met Gly Met Gly Thr Ser Gly Pro Asn 
    130                 135                 140                 


Gln Gly Pro Thr Gln Ser Thr Gly Met Met Asn Ser Pro Val Asn Gln 
145                 150                 155                 160 


Pro Ala Met Gly Met Asn Thr Gly Met Asn Ala Gly Met Asn Pro Gly 
                165                 170                 175     


Met Leu Ala Ala Gly Asn Gly Gln Gly Ile Met Pro Asn Gln Val Met 
            180                 185                 190         


Asn Gly Ser Ile Gly Ala Gly Arg Gly Arg Gln Asn Met Gln Tyr Pro 
        195                 200                 205             


Asn Pro Gly Met Gly Ser Ala Gly Asn Leu Leu Thr Glu Pro Leu Gln 
    210                 215                 220                 


Gln Gly Ser Pro Gln Met Gly Gly Gln Thr Gly Leu Arg Gly Pro Gln 
225                 230                 235                 240 


Pro Leu Lys Met Gly Met Met Asn Asn Pro Asn Pro Tyr Gly Ser Pro 
                245                 250                 255     


Tyr Thr Gln Asn Pro Gly Gln Gln Ile Gly Ala Ser Gly Leu Gly Leu 
            260                 265                 270         


Gln Ile Gln Thr Lys Thr Val Leu Ser Asn Asn Leu Ser Pro Phe Ala 
        275                 280                 285             


Met Asp Lys Lys Ala Val Pro Gly Gly Gly Met Pro Asn Met Gly Gln 
    290                 295                 300                 


Gln Pro Ala Pro Gln Val Gln Gln Pro Gly Leu Val Thr Pro Val Ala 
305                 310                 315                 320 


Gln Gly Met Gly Ser Gly Ala His Thr Ala Asp Pro Glu Lys Arg Lys 
                325                 330                 335     


Leu Ile Gln Gln Gln Leu Val Leu Leu Leu His Ala His Lys Cys Gln 
            340                 345                 350         


Arg Arg Glu Gln Ala Asn Gly Glu Val Arg Gln Cys Asn Leu Pro His 
        355                 360                 365             


Cys Arg Thr Met Lys Asn Val Leu Asn His Met Thr His Cys Gln Ser 
    370                 375                 380                 


Gly Lys Ser Cys Gln Val Ala His Cys Ala Ser Ser Arg Gln Ile Ile 
385                 390                 395                 400 


Ser His Trp Lys Asn Cys Thr Arg His Asp Cys Pro Val Cys Leu Pro 
                405                 410                 415     


Leu Lys Asn Ala Gly Asp Lys Arg Asn Gln Gln Pro Ile Leu Thr Gly 
            420                 425                 430         


Ala Pro Val Gly Leu Gly Asn Pro Ser Ser Leu Gly Val Gly Gln Gln 
        435                 440                 445             


Ser Ala Pro Asn Leu Ser Thr Val Ser Gln Ile Asp Pro Ser Ser Ile 
    450                 455                 460                 


Glu Arg Ala Tyr Ala Ala Leu Gly Leu Pro Tyr Gln Val Asn Gln Met 
465                 470                 475                 480 


Pro Thr Gln Pro Gln Val Gln Ala Lys Asn Gln Gln Asn Gln Gln Pro 
                485                 490                 495     


Gly Gln Ser Pro Gln Gly Met Arg Pro Met Ser Asn Met Ser Ala Ser 
            500                 505                 510         


Pro Met Gly Val Asn Gly Gly Val Gly Val Gln Thr Pro Ser Leu Leu 
        515                 520                 525             


Ser Asp Ser Met Leu His Ser Ala Ile Asn Ser Gln Asn Pro Met Met 
    530                 535                 540                 


Ser Glu Asn Ala Ser Val Pro Ser Leu Gly Pro Met Pro Thr Ala Ala 
545                 550                 555                 560 


Gln Pro Ser Thr Thr Gly Ile Arg Lys Gln Trp His Glu Asp Ile Thr 
                565                 570                 575     


Gln Asp Leu Arg Asn His Leu Val His Lys Leu Val Gln Ala Ile Phe 
            580                 585                 590         


Pro Thr Pro Asp Pro Ala Ala Leu Lys Asp Arg Arg Met Glu Asn Leu 
        595                 600                 605             


Val Ala Tyr Ala Arg Lys Val Glu Gly Asp Met Tyr Glu Ser Ala Asn 
    610                 615                 620                 


Asn Arg Ala Glu Tyr Tyr His Leu Leu Ala Glu Lys Ile Tyr Lys Ile 
625                 630                 635                 640 


Gln Lys Glu Leu Glu Glu Lys Arg Arg Thr Arg Leu Gln Lys Gln Asn 
                645                 650                 655     


Met Leu Pro Asn Ala Ala Gly Met Val Pro Val Ser Met Asn Pro Gly 
            660                 665                 670         


Pro Asn Met Gly Gln Pro Gln Pro Gly Met Thr Ser Asn Gly Pro Leu 
        675                 680                 685             


Pro Asp Pro Ser Met Ile Arg Gly Ser Val Pro Asn Gln Met Met Pro 
    690                 695                 700                 


Arg Ile Thr Pro Gln Ser Gly Leu Asn Gln Phe Gly Gln Met Ser Met 
705                 710                 715                 720 


Ala Gln Pro Pro Ile Val Pro Arg Gln Thr Pro Pro Leu Gln His His 
                725                 730                 735     


Gly Gln Leu Ala Gln Pro Gly Ala Leu Asn Pro Pro Met Gly Tyr Gly 
            740                 745                 750         


Pro Arg Met Gln Gln Pro Ser Asn Gln Gly Gln Phe Leu Pro Gln Thr 
        755                 760                 765             


Gln Phe Pro Ser Gln Gly Met Asn Val Thr Asn Ile Pro Leu Ala Pro 
    770                 775                 780                 


Ser Ser Gly Gln Ala Pro Val Ser Gln Ala Gln Met Ser Ser Ser Ser 
785                 790                 795                 800 


Cys Pro Val Asn Ser Pro Ile Met Pro Pro Gly Ser Gln Gly Ser His 
                805                 810                 815     


Ile His Cys Pro Gln Leu Pro Gln Pro Ala Leu His Gln Asn Ser Pro 
            820                 825                 830         


Ser Pro Val Pro Ser Arg Thr Pro Thr Pro His His Thr Pro Pro Ser 
        835                 840                 845             


Ile Gly Ala Gln Gln Pro Pro Ala Thr Thr Ile Pro Ala Pro Val Pro 
    850                 855                 860                 


Thr Pro Pro Ala Met Pro Pro Gly Pro Gln Ser Gln Ala Leu His Pro 
865                 870                 875                 880 


Pro Pro Arg Gln Thr Pro Thr Pro Pro Thr Thr Gln Leu Pro Gln Gln 
                885                 890                 895     


Val Gln Pro Ser Leu Pro Ala Ala Pro Ser Ala Asp Gln Pro Gln Gln 
            900                 905                 910         


Gln Pro Arg Ser Gln Gln Ser Thr Ala Ala Ser Val Pro Thr Pro Thr 
        915                 920                 925             


Ala Pro Leu Leu Pro Pro Gln Pro Ala Thr Pro Leu Ser Gln Pro Ala 
    930                 935                 940                 


Val Ser Ile Glu Gly Gln Val Ser Asn Pro Pro Ser Thr Ser Ser Thr 
945                 950                 955                 960 


Glu Val Asn Ser Gln Ala Ile Ala Glu Lys Gln Pro Ser Gln Glu Val 
                965                 970                 975     


Lys Met Glu Ala Lys Met Glu Val Asp Gln Pro Glu Pro Ala Asp Thr 
            980                 985                 990         


Gln Pro Glu Asp Ile Ser Glu Ser  Lys Val Glu Asp Cys  Lys Met Glu 
        995                 1000                 1005             


Ser Thr  Glu Thr Glu Glu Arg  Ser Thr Glu Leu Lys  Thr Glu Ile 
    1010                 1015                 1020             


Lys Glu  Glu Glu Asp Gln Pro  Ser Thr Ser Ala Thr  Gln Ser Ser 
    1025                 1030                 1035             


Pro Ala  Pro Gly Gln Ser Lys  Lys Lys Ile Phe Lys  Pro Glu Glu 
    1040                 1045                 1050             


Leu Arg  Gln Ala Leu Met Pro  Thr Leu Glu Ala Leu  Tyr Arg Gln 
    1055                 1060                 1065             


Asp Pro  Glu Ser Leu Pro Phe  Arg Gln Pro Val Asp  Pro Gln Leu 
    1070                 1075                 1080             


Leu Gly  Ile Pro Asp Tyr Phe  Asp Ile Val Lys Ser  Pro Met Asp 
    1085                 1090                 1095             


Leu Ser  Thr Ile Lys Arg Lys  Leu Asp Thr Gly Gln  Tyr Gln Glu 
    1100                 1105                 1110             


Pro Trp  Gln Tyr Val Asp Asp  Ile Trp Leu Met Phe  Asn Asn Ala 
    1115                 1120                 1125             


Trp Leu  Tyr Asn Arg Lys Thr  Ser Arg Val Tyr Lys  Tyr Cys Ser 
    1130                 1135                 1140             


Lys Leu  Ser Glu Val Phe Glu  Gln Glu Ile Asp Pro  Val Met Gln 
    1145                 1150                 1155             


Ser Leu  Gly Tyr Cys Cys Gly  Arg Lys Leu Glu Phe  Ser Pro Gln 
    1160                 1165                 1170             


Thr Leu  Cys Cys Tyr Gly Lys  Gln Leu Cys Thr Ile  Pro Arg Asp 
    1175                 1180                 1185             


Ala Thr  Tyr Tyr Ser Tyr Gln  Asn Arg Tyr His Phe  Cys Glu Lys 
    1190                 1195                 1200             


Cys Phe  Asn Glu Ile Gln Gly  Glu Ser Val Ser Leu  Gly Asp Asp 
    1205                 1210                 1215             


Pro Ser  Gln Pro Gln Thr Thr  Ile Asn Lys Glu Gln  Phe Ser Lys 
    1220                 1225                 1230             


Arg Lys  Asn Asp Thr Leu Asp  Pro Glu Leu Phe Val  Glu Cys Thr 
    1235                 1240                 1245             


Glu Cys  Gly Arg Lys Met His  Gln Ile Cys Val Leu  His His Glu 
    1250                 1255                 1260             


Ile Ile  Trp Pro Ala Gly Phe  Val Cys Asp Gly Cys  Leu Lys Lys 
    1265                 1270                 1275             


Ser Ala  Arg Thr Arg Lys Glu  Asn Lys Phe Ser Ala  Lys Arg Leu 
    1280                 1285                 1290             


Pro Ser  Thr Arg Leu Gly Thr  Phe Leu Glu Asn Arg  Val Asn Asp 
    1295                 1300                 1305             


Phe Leu  Arg Arg Gln Asn His  Pro Glu Ser Gly Glu  Val Thr Val 
    1310                 1315                 1320             


Arg Val  Val His Ala Ser Asp  Lys Thr Val Glu Val  Lys Pro Gly 
    1325                 1330                 1335             


Met Lys  Ala Arg Phe Val Asp  Ser Gly Glu Met Ala  Glu Ser Phe 
    1340                 1345                 1350             


Pro Tyr  Arg Thr Lys Ala Leu  Phe Ala Phe Glu Glu  Ile Asp Gly 
    1355                 1360                 1365             


Val Asp  Leu Cys Phe Phe Gly  Met His Val Gln Glu  Tyr Gly Ser 
    1370                 1375                 1380             


Asp Cys  Pro Pro Pro Asn Gln  Arg Arg Val Tyr Ile  Ser Tyr Leu 
    1385                 1390                 1395             


Asp Ser  Val His Phe Phe Arg  Pro Lys Cys Leu Arg  Thr Ala Val 
    1400                 1405                 1410             


Tyr His  Glu Ile Leu Ile Gly  Tyr Leu Glu Tyr Val  Lys Lys Leu 
    1415                 1420                 1425             


Gly Tyr  Thr Thr Gly His Ile  Trp Ala Cys Pro Pro  Ser Glu Gly 
    1430                 1435                 1440             


Asp Asp  Tyr Ile Phe His Cys  His Pro Pro Asp Gln  Lys Ile Pro 
    1445                 1450                 1455             


Lys Pro  Lys Arg Leu Gln Glu  Trp Tyr Lys Lys Met  Leu Asp Lys 
    1460                 1465                 1470             


Ala Val  Ser Glu Arg Ile Val  His Asp Tyr Lys Asp  Ile Phe Lys 
    1475                 1480                 1485             


Gln Ala  Thr Glu Asp Arg Leu  Thr Ser Ala Lys Glu  Leu Pro Tyr 
    1490                 1495                 1500             


Phe Glu  Gly Asp Phe Trp Pro  Asn Val Leu Glu Glu  Ser Ile Lys 
    1505                 1510                 1515             


Glu Leu  Glu Gln Glu Glu Glu  Glu Arg Lys Arg Glu  Glu Asn Thr 
    1520                 1525                 1530             


Ser Asn  Glu Ser Thr Asp Val  Thr Lys Gly Asp Ser  Lys Asn Ala 
    1535                 1540                 1545             


Lys Lys  Lys Asn Asn Lys Lys  Thr Ser Lys Asn Lys  Ser Ser Leu 
    1550                 1555                 1560             


Ser Arg  Gly Asn Lys Lys Lys  Pro Gly Met Pro Asn  Val Ser Asn 
    1565                 1570                 1575             


Asp Leu  Ser Gln Lys Leu Tyr  Ala Thr Met Glu Lys  His Lys Glu 
    1580                 1585                 1590             


Val Phe  Phe Val Ile Arg Leu  Ile Ala Gly Pro Ala  Ala Asn Ser 
    1595                 1600                 1605             


Leu Pro  Pro Ile Val Asp Pro  Asp Pro Leu Ile Pro  Cys Asp Leu 
    1610                 1615                 1620             


Met Asp  Gly Arg Asp Ala Phe  Leu Thr Leu Ala Arg  Asp Lys His 
    1625                 1630                 1635             


Leu Glu  Phe Ser Ser Leu Arg  Arg Ala Gln Trp Ser  Thr Met Cys 
    1640                 1645                 1650             


Met Leu  Val Glu Leu His Thr  Gln Ser Gln Asp Arg  Phe Val Tyr 
    1655                 1660                 1665             


Thr Cys  Asn Glu Cys Lys His  His Val Glu Thr Arg  Trp His Cys 
    1670                 1675                 1680             


Thr Val  Cys Glu Asp Tyr Asp  Leu Cys Ile Thr Cys  Tyr Asn Thr 
    1685                 1690                 1695             


Lys Asn  His Asp His Lys Met  Glu Lys Leu Gly Leu  Gly Leu Asp 
    1700                 1705                 1710             


Asp Glu  Ser Asn Asn Gln Gln  Ala Ala Ala Thr Gln  Ser Pro Gly 
    1715                 1720                 1725             


Asp Ser  Arg Arg Leu Ser Ile  Gln Arg Cys Ile Gln  Ser Leu Val 
    1730                 1735                 1740             


His Ala  Cys Gln Cys Arg Asn  Ala Asn Cys Ser Leu  Pro Ser Cys 
    1745                 1750                 1755             


Gln Lys  Met Lys Arg Val Val  Gln His Thr Lys Gly  Cys Lys Arg 
    1760                 1765                 1770             


Lys Thr  Asn Gly Gly Cys Pro  Ile Cys Lys Gln Leu  Ile Ala Leu 
    1775                 1780                 1785             


Cys Cys  Tyr His Ala Lys His  Cys Gln Glu Asn Lys  Cys Pro Val 
    1790                 1795                 1800             


Pro Phe  Cys Leu Asn Ile Lys  Gln Lys Leu Arg Gln  Gln Gln Leu 
    1805                 1810                 1815             


Gln His  Arg Leu Gln Gln Ala  Gln Met Leu Arg Arg  Arg Met Ala 
    1820                 1825                 1830             


Ser Met  Gln Arg Thr Gly Val  Val Gly Gln Gln Gln  Gly Leu Pro 
    1835                 1840                 1845             


Ser Pro  Thr Pro Ala Thr Pro  Thr Thr Pro Thr Gly  Gln Gln Pro 
    1850                 1855                 1860             


Thr Thr  Pro Gln Thr Pro Gln  Pro Thr Ser Gln Pro  Gln Pro Thr 
    1865                 1870                 1875             


Pro Pro  Asn Ser Met Pro Pro  Tyr Leu Pro Arg Thr  Gln Ala Ala 
    1880                 1885                 1890             


Gly Pro  Val Ser Gln Gly Lys  Ala Ala Gly Gln Val  Thr Pro Pro 
    1895                 1900                 1905             


Thr Pro  Pro Gln Thr Ala Gln  Pro Pro Leu Pro Gly  Pro Pro Pro 
    1910                 1915                 1920             


Ala Ala  Val Glu Met Ala Met  Gln Ile Gln Arg Ala  Ala Glu Thr 
    1925                 1930                 1935             


Gln Arg  Gln Met Ala His Val  Gln Ile Phe Gln Arg  Pro Ile Gln 
    1940                 1945                 1950             


His Gln  Met Pro Pro Met Thr  Pro Met Ala Pro Met  Gly Met Asn 
    1955                 1960                 1965             


Pro Pro  Pro Met Thr Arg Gly  Pro Ser Gly His Leu  Glu Pro Gly 
    1970                 1975                 1980             


Met Gly  Pro Thr Gly Met Gln  Gln Gln Pro Pro Trp  Ser Gln Gly 
    1985                 1990                 1995             


Gly Leu  Pro Gln Pro Gln Gln  Leu Gln Ser Gly Met  Pro Arg Pro 
    2000                 2005                 2010             


Ala Met  Met Ser Val Ala Gln  His Gly Gln Pro Leu  Asn Met Ala 
    2015                 2020                 2025             


Pro Gln  Pro Gly Leu Gly Gln  Val Gly Ile Ser Pro  Leu Lys Pro 
    2030                 2035                 2040             


Gly Thr  Val Ser Gln Gln Ala  Leu Gln Asn Leu Leu  Arg Thr Leu 
    2045                 2050                 2055             


Arg Ser  Pro Ser Ser Pro Leu  Gln Gln Gln Gln Val  Leu Ser Ile 
    2060                 2065                 2070             


Leu His  Ala Asn Pro Gln Leu  Leu Ala Ala Phe Ile  Lys Gln Arg 
    2075                 2080                 2085             


Ala Ala  Lys Tyr Ala Asn Ser  Asn Pro Gln Pro Ile  Pro Gly Gln 
    2090                 2095                 2100             


Pro Gly  Met Pro Gln Gly Gln  Pro Gly Leu Gln Pro  Pro Thr Met 
    2105                 2110                 2115             


Pro Gly  Gln Gln Gly Val His  Ser Asn Pro Ala Met  Gln Asn Met 
    2120                 2125                 2130             


Asn Pro  Met Gln Ala Gly Val  Gln Arg Ala Gly Leu  Pro Gln Gln 
    2135                 2140                 2145             


Gln Pro  Gln Gln Gln Leu Gln  Pro Pro Met Gly Gly  Met Ser Pro 
    2150                 2155                 2160             


Gln Ala  Gln Gln Met Asn Met  Asn His Asn Thr Met  Pro Ser Gln 
    2165                 2170                 2175             


Phe Arg  Asp Ile Leu Arg Arg  Gln Gln Met Met Gln  Gln Gln Gln 
    2180                 2185                 2190             


Gln Gln  Gly Ala Gly Pro Gly  Ile Gly Pro Gly Met  Ala Asn His 
    2195                 2200                 2205             


Asn Gln  Phe Gln Gln Pro Gln  Gly Val Gly Tyr Pro  Pro Gln Gln 
    2210                 2215                 2220             


Gln Gln  Arg Met Gln His His  Met Gln Gln Met Gln  Gln Gly Asn 
    2225                 2230                 2235             


Met Gly  Gln Ile Gly Gln Leu  Pro Gln Ala Leu Gly  Ala Glu Ala 
    2240                 2245                 2250             


Gly Ala  Ser Leu Gln Ala Tyr  Gln Gln Arg Leu Leu  Gln Gln Gln 
    2255                 2260                 2265             


Met Gly  Ser Pro Val Gln Pro  Asn Pro Met Ser Pro  Gln Gln His 
    2270                 2275                 2280             


Met Leu  Pro Asn Gln Ala Gln  Ser Pro His Leu Gln  Gly Gln Gln 
    2285                 2290                 2295             


Ile Pro  Asn Ser Leu Ser Asn  Gln Val Arg Ser Pro  Gln Pro Val 
    2300                 2305                 2310             


Pro Ser  Pro Arg Pro Gln Ser  Gln Pro Pro His Ser  Ser Pro Ser 
    2315                 2320                 2325             


Pro Arg  Met Gln Pro Gln Pro  Ser Pro His His Val  Ser Pro Gln 
    2330                 2335                 2340             


Thr Ser  Ser Pro His Pro Gly  Leu Val Ala Ala Gln  Ala Asn Pro 
    2345                 2350                 2355             


Met Glu  Gln Gly His Phe Ala  Ser Pro Asp Gln Asn  Ser Met Leu 
    2360                 2365                 2370             


Ser Gln  Leu Ala Ser Asn Pro  Gly Met Ala Asn Leu  His Gly Ala 
    2375                 2380                 2385             


Ser Ala  Thr Asp Leu Gly Leu  Ser Thr Asp Asn Ser  Asp Leu Asn 
    2390                 2395                 2400             


Ser Asn  Leu Ser Gln Ser Thr  Leu Asp Ile His 
    2405                 2410                 


<210>  4368
<211>  700
<212>  PRT
<213>  homo sapiens

<400>  4368

Met Ser Arg Arg Thr Arg Cys Glu Asp Leu Asp Glu Leu His Tyr Gln 
1               5                   10                  15      


Asp Thr Asp Ser Asp Val Pro Glu Gln Arg Asp Ser Lys Cys Lys Val 
            20                  25                  30          


Lys Trp Thr His Glu Glu Asp Glu Gln Leu Arg Ala Leu Val Arg Gln 
        35                  40                  45              


Phe Gly Gln Gln Asp Trp Lys Phe Leu Ala Ser His Phe Pro Asn Arg 
    50                  55                  60                  


Thr Asp Gln Gln Cys Gln Tyr Arg Trp Leu Arg Val Leu Asn Pro Asp 
65                  70                  75                  80  


Leu Val Lys Gly Pro Trp Thr Lys Glu Glu Asp Gln Lys Val Ile Glu 
                85                  90                  95      


Leu Val Lys Lys Tyr Gly Thr Lys Gln Trp Thr Leu Ile Ala Lys His 
            100                 105                 110         


Leu Lys Gly Arg Leu Gly Lys Gln Cys Arg Glu Arg Trp His Asn His 
        115                 120                 125             


Leu Asn Pro Glu Val Lys Lys Ser Cys Trp Thr Glu Glu Glu Asp Arg 
    130                 135                 140                 


Ile Ile Cys Glu Ala His Lys Val Leu Gly Asn Arg Trp Ala Glu Ile 
145                 150                 155                 160 


Ala Lys Met Leu Pro Gly Arg Thr Asp Asn Ala Val Lys Asn His Trp 
                165                 170                 175     


Asn Ser Thr Ile Lys Arg Lys Val Asp Thr Gly Gly Phe Leu Ser Glu 
            180                 185                 190         


Ser Lys Asp Cys Lys Pro Pro Val Tyr Leu Leu Leu Glu Leu Glu Asp 
        195                 200                 205             


Lys Asp Gly Leu Gln Ser Ala Gln Pro Thr Glu Gly Gln Gly Ser Leu 
    210                 215                 220                 


Leu Thr Asn Trp Pro Ser Val Pro Pro Thr Ile Lys Glu Glu Glu Asn 
225                 230                 235                 240 


Ser Glu Glu Glu Leu Ala Ala Ala Thr Thr Ser Lys Glu Gln Glu Pro 
                245                 250                 255     


Ile Gly Thr Asp Leu Asp Ala Val Arg Thr Pro Glu Pro Leu Glu Glu 
            260                 265                 270         


Phe Pro Lys Arg Glu Asp Gln Glu Gly Ser Pro Pro Glu Thr Ser Leu 
        275                 280                 285             


Pro Tyr Lys Trp Val Val Glu Ala Ala Asn Leu Leu Ile Pro Ala Val 
    290                 295                 300                 


Gly Ser Ser Leu Ser Glu Ala Leu Asp Leu Ile Glu Ser Asp Pro Asp 
305                 310                 315                 320 


Ala Trp Cys Asp Leu Ser Lys Phe Asp Leu Pro Glu Glu Pro Ser Ala 
                325                 330                 335     


Glu Asp Ser Ile Asn Asn Ser Leu Val Gln Leu Gln Ala Ser His Gln 
            340                 345                 350         


Gln Gln Val Leu Pro Pro Arg Gln Pro Ser Ala Leu Val Pro Ser Val 
        355                 360                 365             


Thr Glu Tyr Arg Leu Asp Gly His Thr Ile Ser Asp Leu Ser Arg Ser 
    370                 375                 380                 


Ser Arg Gly Glu Leu Ile Pro Ile Ser Pro Ser Thr Glu Val Gly Gly 
385                 390                 395                 400 


Ser Gly Ile Gly Thr Pro Pro Ser Val Leu Lys Arg Gln Arg Lys Arg 
                405                 410                 415     


Arg Val Ala Leu Ser Pro Val Thr Glu Asn Ser Thr Ser Leu Ser Phe 
            420                 425                 430         


Leu Asp Ser Cys Asn Ser Leu Thr Pro Lys Ser Thr Pro Val Lys Thr 
        435                 440                 445             


Leu Pro Phe Ser Pro Ser Gln Phe Leu Asn Phe Trp Asn Lys Gln Asp 
    450                 455                 460                 


Thr Leu Glu Leu Glu Ser Pro Ser Leu Thr Ser Thr Pro Val Cys Ser 
465                 470                 475                 480 


Gln Lys Val Val Val Thr Thr Pro Leu His Arg Asp Lys Thr Pro Leu 
                485                 490                 495     


His Gln Lys His Ala Ala Phe Val Thr Pro Asp Gln Lys Tyr Ser Met 
            500                 505                 510         


Asp Asn Thr Pro His Thr Pro Thr Pro Phe Lys Asn Ala Leu Glu Lys 
        515                 520                 525             


Tyr Gly Pro Leu Lys Pro Leu Pro Gln Thr Pro His Leu Glu Glu Asp 
    530                 535                 540                 


Leu Lys Glu Val Leu Arg Ser Glu Ala Gly Ile Glu Leu Ile Ile Glu 
545                 550                 555                 560 


Asp Asp Ile Arg Pro Glu Lys Gln Lys Arg Lys Pro Gly Leu Arg Arg 
                565                 570                 575     


Ser Pro Ile Lys Lys Val Arg Lys Ser Leu Ala Leu Asp Ile Val Asp 
            580                 585                 590         


Glu Asp Val Lys Leu Met Met Ser Thr Leu Pro Lys Ser Leu Ser Leu 
        595                 600                 605             


Pro Thr Thr Ala Pro Ser Asn Ser Ser Ser Leu Thr Leu Ser Gly Ile 
    610                 615                 620                 


Lys Glu Asp Asn Ser Leu Leu Asn Gln Gly Phe Leu Gln Ala Lys Pro 
625                 630                 635                 640 


Glu Lys Ala Ala Val Ala Gln Lys Pro Arg Ser His Phe Thr Thr Pro 
                645                 650                 655     


Ala Pro Met Ser Ser Ala Trp Lys Thr Val Ala Cys Gly Gly Thr Arg 
            660                 665                 670         


Asp Gln Leu Phe Met Gln Glu Lys Ala Arg Gln Leu Leu Gly Arg Leu 
        675                 680                 685             


Lys Pro Ser His Thr Ser Arg Thr Leu Ile Leu Ser 
    690                 695                 700 


<210>  4369
<211>  84
<212>  PRT
<213>  homo sapiens

<400>  4369

Met Leu Ala Glu Ile His Pro Lys Ala Gly Leu Gln Ser Leu Gln Phe 
1               5                   10                  15      


Ile Met Glu Leu Leu Tyr Trp Leu Leu Glu Gly Gly Asp Ser Glu Asp 
            20                  25                  30          


Lys Glu Asp Ala Thr Gly Asn Val Glu Met Lys Asn Ile Gln Pro Leu 
        35                  40                  45              


Val Phe Glu Ile Ser Cys Asp Val Phe Gln Ser Arg Cys Lys Glu His 
    50                  55                  60                  


Gly Lys Ile Lys Val Leu Glu Trp Phe Lys Tyr Val Leu Gly Ile Pro 
65                  70                  75                  80  


Val Tyr Arg Leu 
                


<210>  4370
<211>  841
<212>  DNA
<213>  homo sapiens

<400>  4370
ggaggagagg tgagcccccg cccgggccag gccctctggc cgcgccgtcc gcccctctag       60

tcgtgtcccc tcgtgggccg aacggacgcg gcggtgcccc gcgcccgacc agacgtcccg      120

tgggctaggg cctgggcctc gggccgcgtc ggcgccggtc gagcctctcc gggtgtcggg      180

gttcggggcg ggcgcgcgtg ggcgtggctc ctctgtccac gcctgttccc ttcgtcgccg      240

cggctctcgt ccgggacacg gctttccgga gtagagccct tggaggtgtt aagtgtgatg      300

cttccataat acatttggat gctgtcagct aagttcactt ctgaactaag gggttcctcc      360

aaatgttggc tgaaattcat cccaaggctg gtctgcaaag tctgcaattc ataatggagc      420

tactgtactg gctattggaa ggaggagatt ctgaagataa ggaggatgcc actggaaatg      480

ttgaaatgaa aaatattcag ccgttggtct ttgaaatttc ctgtgatgtg tttcaatcta      540

gatgcaaaga acatggaaaa atcaaagtgc tcgagtggtt taaatatgtt ttgggtattc      600

ctgtttatag actataatac ttttccaatt aaaatcctca gttgtcacgc agaagaaggt      660

taagctgtat ttgattgcca gttttactga aaatgcttag tattttacag tatcaccaaa      720

tatattttgt ttagccaagg tataggaaaa ataaaataaa ttgtataggt tgactttttt      780

ctaaaatgtc tttattggat tgaatgaatg tttatacctg aaaaaaaaag gttcaaaaaa      840

a                                                                      841


<210>  4371
<211>  924
<212>  DNA
<213>  homo sapiens

<400>  4371
ggaggagagg tgagcccccg cccgggccag gccctctggc cgcgccgtcc gcccctctag       60

tcgtgtcccc tcgtgggccg aacggacgcg gcggtgcccc gcgcccgacc agacgtcccg      120

tgggctaggg cctgggcctc gggccgcgtc ggcgccggtc gagcctctcc gggtgtcggg      180

gttcggggcg ggcgcgcgtg ggcgtggctc ctctgtccac gcctgttccc ttcgtcgccg      240

cggctctcgt ccgggacacg gctttccgga gtagagccct tggaggtgtt aagtgtgatg      300

cttccataat acatttggat gctgtcagct aagttcactt ctgaactaag gggttcctcc      360

aaatgttggc tgaaattcat cccaaggctg gtctgcaaag tctgcaattc ataatggagc      420

tactgtactg gctattggaa ggaggagatt ctgaagataa ggaggtaaaa cctgtttaga      480

aattaaaaat gagttacgat ttaaagaaaa ttcagatgac tcattgtgag tgctagttct      540

cttgtaggat gccactggaa atgttgaaat gaaaaatatt cagccgttgg tctttgaaat      600

ttcctgtgat gtgtttcaat ctagatgcaa agaacatgga aaaatcaaag tgctcgagtg      660

gtttaaatat gttttgggta ttcctgttta tagactataa tacttttcca attaaaatcc      720

tcagttgtca cgcagaagaa ggttaagctg tatttgattg ccagttttac tgaaaatgct      780

tagtatttta cagtatcacc aaatatattt tgtttagcca aggtatagga aaaataaaat      840

aaattgtata ggttgacttt tttctaaaat gtctttattg gattgaatga atgtttatac      900

ctgaaaaaaa aaggttcaaa aaaa                                             924


<210>  4372
<211>  1146
<212>  DNA
<213>  homo sapiens

<400>  4372
ggggtctcga tcgcgctatt gtcatggaga cgggaagctg gctgcagcgg cggcggggac       60

cgtggggccg aggtggctgc cagccggcca atgtctaagc gaggcggagc ggcccaggcg      120

gcccgagcct gggggagcgc gcagccggcc agtggcggcc tcgccggcgg cctcttcccg      180

ggctcgcagt aggcccgagt cgtcgccggg agctcctggg agcagcgtcc ccgccctgct      240

cccctcgctc ccgcctcttg cggccccacg gcccctcagc gcccgccccc ggctccgccc      300

gccgcagccg cagcccctgg cgctaacggt cggtaacggc ccgcgcgcgc cgcccgccgg      360

gggctcgcgc cagccacgag ggagcgtccg cggcccgcgc gcccgcgcgg cggaggagag      420

gtgttaagtg tgatgcttcc ataatacatt tggatgctgt cagctaagtt cacttctgaa      480

ctaaggggtt cctccaaatg ttggctgaaa ttcatcccaa ggctggtctg caattaccta      540

tttcttttaa gaataaattt agtgggaata tcagttccag tcatgggtac caaacttttt      600

tagtgacaga gtacacacag agtctgcaat tcataatgga gctactgtac tggctattgg      660

aaggaggaga ttctgaagat aaggaggtaa aacctgttta gaaattaaaa atgagttacg      720

atttaaagaa aattcagatg actcattgtg agtgctagtt ctcttgtagg atgccactgg      780

aaatgttgaa atgaaaaata ttcagccgtt ggtctttgaa atttcctgtg atgtgtttca      840

atctagatgc aaagaacatg gaaaaatcaa agtgctcgag tggtttaaat atgttttggg      900

tattcctgtt tatagactat aatacttttc caattaaaat cctcagttgt cacgcagaag      960

aaggttaagc tgtatttgat tgccagtttt actgaaaatg cttagtattt tacagtatca     1020

ccaaatatat tttgtttagc caaggtatag gaaaaataaa ataaattgta taggttgact     1080

tttttctaaa atgtctttat tggattgaat gaatgtttat acctgaaaaa aaaaggttca     1140

aaaaaa                                                                1146


<210>  4373
<211>  1059
<212>  DNA
<213>  homo sapiens

<400>  4373
ggggtctcga tcgcgctatt gtcatggaga cgggaagctg gctgcagcgg cggcggggac       60

cgtggggccg aggtggctgc cagccggcca atgtctaagc gaggcggagc ggcccaggcg      120

gcccgagcct gggggagcgc gcagccggcc agtggcggcc tcgccggcgg cctcttcccg      180

ggctcgcagt aggcccgagt cgtcgccggg agctcctggg agcagcgtcc ccgccctgct      240

cccctcgctc ccgcctcttg cggccccacg gcccctcagc gcccgccccc ggctccgccc      300

gccgcagccg cagcccctgg cgctaacggt cggtaacggc ccgcgcgcgc cgcccgccgg      360

gggctcgcgc cagccacgag ggagcgtccg cggcccgcgc gcccgcgcgg cggaggagag      420

gtgttaagtg tgatgcttcc ataatacatt tggatgctgt cagctaagtt cacttctgaa      480

ctaaggggtt cctccaaatg ttggctgaaa ttcatcccaa ggctggtctg caaagtctgc      540

aattcataat ggagctactg tactggctat tggaaggagg agattctgaa gataaggagg      600

taaaacctgt ttagaaatta aaaatgagtt acgatttaaa gaaaattcag atgactcatt      660

gtgagtgcta gttctcttgt aggatgccac tggaaatgtt gaaatgaaaa atattcagcc      720

gttggtcttt gaaatttcct gtgatgtgtt tcaatctaga tgcaaagaac atggaaaaat      780

caaagtgctc gagtggttta aatatgtttt gggtattcct gtttatagac tataatactt      840

ttccaattaa aatcctcagt tgtcacgcag aagaaggtta agctgtattt gattgccagt      900

tttactgaaa atgcttagta ttttacagta tcaccaaata tattttgttt agccaaggta      960

taggaaaaat aaaataaatt gtataggttg acttttttct aaaatgtctt tattggattg     1020

aatgaatgtt tatacctgaa aaaaaaaggt tcaaaaaaa                            1059


<210>  4374
<211>  852
<212>  DNA
<213>  homo sapiens

<400>  4374
ggaggagagg tgagcccccg cccgggccag gccctctggc cgcgccgtcc gcccctctag       60

tcgtgtcccc tcgtgggccg aacggacgcg gcggtgcccc gcgcccgacc agacgtcccg      120

tgggctaggg cctgggcctc gggccgcgtc ggcgccggtc gagcctctcc gggtgtcggg      180

gttcggggcg ggcgcgcgtg ggcgtggctc ctctgtccac gcctgttccc ttcgtcgccg      240

cggctctcgt ccgggacacg gctttccgga gtagagccct tggaggtgtt aagtgtgatg      300

cttccataat acatttggat gctgtcagct aagttcactt ctgaactaag gggttcctcc      360

aaatgttggc tgaaattcat cccaaggctg gtctgcaaag tctgcaattc ataatggagc      420

tactgtactg gctattggaa ggaggagatt ctgaagataa ggagttctct tgtaggatgc      480

cactggaaat gttgaaatga aaaatattca gccgttggtc tttgaaattt cctgtgatgt      540

gtttcaatct agatgcaaag aacatggaaa aatcaaagtg ctcgagtggt ttaaatatgt      600

tttgggtatt cctgtttata gactataata cttttccaat taaaatcctc agttgtcacg      660

cagaagaagg ttaagctgta tttgattgcc agttttactg aaaatgctta gtattttaca      720

gtatcaccaa atatattttg tttagccaag gtataggaaa aataaaataa attgtatagg      780

ttgacttttt tctaaaatgt ctttattgga ttgaatgaat gtttatacct gaaaaaaaaa      840

ggttcaaaaa aa                                                          852


<210>  4375
<211>  284
<212>  DNA
<213>  homo sapiens

<400>  4375
actgatgctt ctgatactgg atgtttagct tcttactgca aaaacataag taaaacagtc       60

aactttacca tttccgtatt ctccatagat tgaagaaatt tataccacat atcgcatatg      120

accatctttc catcaaatca atgtagagat aatgtaaact gaaaaaaaat ctgcaagata      180

atgtaactga atgttttaaa aacagaactt gtcactttat ataaaagaat agtatgctct      240

atttcctgaa tggatgtgga aatgaaagct agcgcacctg cact                       284


<210>  4376
<211>  434
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (86)..(86)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (95)..(95)
<223>  n is a, c, g, or t

<400>  4376
aatgctatac tgtcaaggta cttgcttgtg tctgaactct agtgcactta tgattttgta       60

gaccatgtga aatttaataa gatacntttt ttttnccttt ctttgtgtgt agtgcagcaa      120

cagtttggtc tgcatttgtt agaagtttaa ctcctaacaa cccaaagacc tatttaacaa      180

ttggtgcata aatgaaagta gtactgtata cttgaaactg tttaagtaca agttgaacaa      240

aaattatgaa aaggtatatt tgcttctcgg gaaagcaaag aagctgcttt aaaaaataaa      300

aaggggacta aaaatttgtt ttgtataaag aggttagccc tgcgcacgta ggactgaatt      360

cagtgatatc cctatacact gccatttagt ggataggtta ttgtacttcc attcatactc      420

tgggcacttg tgtt                                                        434


<210>  4377
<211>  379
<212>  DNA
<213>  homo sapiens

<400>  4377
gctgcaggtt ttttgaactc acttctggag gtgcagagcc acaaacgcac tttcggggcc       60

tagttttgct cgaatatgaa tttagatagg tatcaagctg taactaagac aatattgata      120

aatgttggat gacatttaat ttaatggagc atgtacttat ttgcatttgc tggcagttca      180

ggcatagtta aagtgagagt tctcctatat ttcataataa gtggtctgcc aaaacccatg      240

tattaaataa attgtccaag tgaaactcga ctaactttgg cctttgtgta tttcctgaag      300

gtaatattgt taactgttaa taaatacttc tgacactaca tttaaatgtt tgcagattct      360

gcaaactaat tgctcattg                                                   379


<210>  4378
<211>  188
<212>  DNA
<213>  homo sapiens

<400>  4378
gtgttcatct gaggactgca tcggtggaca ctggtattta tttatgttag ctccaagcgg       60

accggtggtt caaaagtgca ttatttagtt tgagctctgt aggtaaaaag gaggtgggaa      120

aaattttaaa acttgagggt aaaaatgtgg aaaacaaacc ctcccatccc ttgtagatta      180

taaataaa                                                               188


<210>  4379
<211>  412
<212>  DNA
<213>  homo sapiens

<400>  4379
ttctccggac ttcgcgtaga acctgcgaat ttcgaagagg aggtggcaaa gtgggagaaa       60

agaggtgtta gggtttgggg tttttttgtt tttgtttttg ttttttaatt tcttgatttc      120

aacattttct cccaccctct cggctgcagc caacgcctct tacctgttct gcggcgccgc      180

gcaccgctgg cagctgaggg ttagaaagcg gggtgtattt tagattttaa gcaaaaattt      240

taaagataaa tccatttttc tctcccaccc ccaacgccat ctccactgca tccgatctca      300

ttatttcggt ggttgcttgg gggtgaacaa ttttgtggct ttttttcccc tataattctg      360

acccgctcag gcttgagggt ttctccggcc tccgctcact gcgtgcacct gg              412


<210>  4380
<211>  451
<212>  DNA
<213>  homo sapiens

<400>  4380
tctttatcct gcgacaacac tttcagcaga ctagcctctc cttatctcac agatcacaag       60

cacccctaga tagtgtgatt ctgtcagata gcatttatgc aaaaatctat gaagttaaaa      120

gatcgtagaa gccaaatgaa atgtacatat ctactgactg atgacaaggg aatttcatta      180

ggaagaaggt aaagaaacat cgttgagtag cctaccttga tttctgtcaa gttcataacc      240

agcttcatat tttaaaggct tcaggtttga aattaagtca actgcatgca gctttgctga      300

taaatgaata attctctttg atgccattta tgagaaaaga cttcaatatc tgttgcctgt      360

catatttaag aaaaattact gtttctactc tctgtatctg attttaaaag aaaaaactat      420

tcatacctgg cttccaggta attgactttg a                                     451


<210>  4381
<211>  343
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (45)..(47)
<223>  n is a, c, g, or t

<400>  4381
gatgtttgat ctgtgttggt catgaagttg tttttttttt ttttnnnaaa aagaaaacca       60

tgatcaacaa gctttgccac gaatttaaga gttttatcaa gatatatcga atacttctac      120

ccatctgttc atagtttatg gactgatgtt ccaagtttgt atcattcctt tgcatataat      180

taaacctgga acaacatgca ctagatttat gtcagaaata tctgttggtt ttccaaaggt      240

tgttaacaga tgaagtttat gtgcaaaaaa gggtaagata taaattcaag gaagaaaaaa      300

agttgatagc taaaaggtag agtgtgtctt cgatataatc caa                        343


<210>  4382
<211>  305
<212>  DNA
<213>  homo sapiens

<400>  4382
ctgcctcttc atatttgaca tgtgtgagag aggggtacaa ctcacgaatc ccttctacag       60

tatctggact acagacattg gaacagagct ggccatggcc ttcatcatcg tggctggaat      120

ctgcctctgc ctctacttcc tgtttctatg cttcatggta tttcaggtgt ttcggaacat      180

cagtgggaag cagtccagcc tgccagctat gagcaaagtc cggcggctac actatgaggg      240

gctaattttt aggttcaagt tcctcatgct tatcaccttg gcctgcgctg ccatgactgt      300

catct                                                                  305


<210>  4383
<211>  385
<212>  DNA
<213>  homo sapiens

<400>  4383
gtaaactgtg catgactcct gcttagcggt cattatcgtg tctgttggtg aaatttttat       60

taaaaggaaa attctgtaga tgcacttatt gaatatgtga ttaggatcta cgtctgagac      120

taggagtcct gaactgctga cgcgaaagag gcgcagttcc caattaatac ggaaatcgct      180

gtgggagaag aatgaaataa gacgtgaagt gtaggaaatc atgaaaagaa caattttgca      240

aattgcattc tgatgcttgt gatgaacaca aatgtacttg tgtagagaca tttccttaag      300

agaaagccta ggagaagccg atttggaggt taatgctgta gaataggact gtataccaaa      360

tgtaatcttt ccaatgctcc aatga                                            385


<210>  4384
<211>  499
<212>  DNA
<213>  homo sapiens

<400>  4384
ttaggtgaag tcgagcactc taattagaga actggaggaa ccacatataa cacttaactt       60

cccctaccct gcccctcccc aaaagaaacc atgacaaacc tagcttttaa aaaatatttt      120

aagaaagaga atgaactgtg gaatttattg gcagccaagg aatgtgtcca agacacatgc      180

tgaggttttg aataaaaagt gaacttttgt aatttgaatt gggtcccgct tagttcttga      240

attgttatga aaatcctata tctgtttgta tatttgcaaa ccctttgtat tataattgtt      300

gatattttcc ctttttaaaa aataccattg aaatcagcat gacaaaaata acactgttgg      360

cacttatagg taacgtgatt gattcagtat cttagagttt acagtttgtg ttttaaaaaa      420

actgaaggtt ttttttttaa gtgcaacatt tctgtatact gtaaaagtta taataactga      480

actgtttggt cgagtcttt                                                   499


<210>  4385
<211>  554
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (345)..(345)
<223>  n is a, c, g, or t

<400>  4385
attataagcg attcccctca acaatccaga gaaagtagtt ctttaaataa gagataattt       60

aaagaaaaat aaatactaga catcaaattt agatctggtt tatgtcaaag gttttaacac      120

tgtacataaa tgttcaattt acttttacaa agatcaagaa tactgcccat tactgtcaca      180

attttccaga tattatataa tgaactcgta atgtaacatt tccttctagc ttcctactga      240

attgtgagct gttacttgtt gaaaaaccat atcacttttc tgttgccatg attttttttt      300

tttcaacaaa aaaccaaagt gcattgtacg ccctttggcc agtcntgtat gtgccttgat      360

ccaacgctac atgtattcag cttttaaaac tccacaaatt tttcatactc cttaaatatg      420

aaaaattatg gtcttattgc tgaataaaac ttttaaaaag tacagaataa ttgtgcttgc      480

tttttcagga ttgtgttact atcactaagt agcaaattgc ccagcacatt agtcctaaac      540

gtcccatgta tttt                                                        554


<210>  4386
<211>  162
<212>  DNA
<213>  homo sapiens

<400>  4386
tagatcttat attggtttgc acaagttccc tggagaaaaa aattgctctg tgtatatctc       60

ttggaaaata agacaatagt atttctcctt tgcaatagca gttataacag atgtgaaaat      120

atacttgact ctaatatgat tatacaaaag agcatggatg ca                         162


<210>  4387
<211>  316
<212>  DNA
<213>  homo sapiens

<400>  4387
tttagaccaa agattgggtt ctagaaaatg cacttggtat actaagtatt aaaacaaaca       60

aaaaggaaag ttgtttcagt tggcaacact gcccattcaa ttgaatcaga aggggacaaa      120

attaacgatt gccttcagtt tgtgttgtgt atattttgat gtatgtggtc actaacaggt      180

cacttttatt ttttctaaat gtagtgaaat gttaatacct attgtactta taggtaaacc      240

ttgcaaatat gtaacctgtg ttgcgcaaat gccgcataaa tttgagtgat tgttaatgtt      300

gtcttaaaat ttcttg                                                      316


<210>  4388
<211>  344
<212>  DNA
<213>  homo sapiens

<400>  4388
atggctgcac gaaacatacc ggtaagtggg gcaagactgt tatcgagtac cggtcacaga       60

agacctcacg cctccccatc attgacattg cacccatgga cataggaggg cccgagcagg      120

aattcggtgt ggacataggg ccggtctgct tcttgtaaaa acctgaaccc agaaacaaca      180

caatccgttg caaacccaaa ggacccaagt actttccaat ctcagtcact ctaggactct      240

gcactgaatg gctgacctga cctgatgtcc attcatccca ccctctcaca gttcggactt      300

ttctcccctc tctttctaag agacctgaac tgggcagact gcaa                       344


<210>  4389
<211>  534
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (252)..(252)
<223>  n is a, c, g, or t

<400>  4389
attttggcgc tcgaagttga tctccccagc gagggcccca gcgtgaagcc agggcccggg       60

aagcaaatgc gagcctgtaa gatagctaac agtgcactta aaggaaaggg gcgtcttgtt      120

cttgttctct tctttatcat acaccaacca aggtttttat atcaaaccaa agggaaataa      180

tactctgcta gaatatggac tgttgaagtc accaaactgt gattattgat tctgtacata      240

ccattgttat tnaaaaaaaa aaaaaaaaga acagagcttt gtatatttga aatgttataa      300

cgcaattgca ctcagcgtgg tatggtaaaa gtttgtcctc ccgtagattc ttactgtgtt      360

gtagatacgg tagggttcct agacaaatat ttatgtactc aagcccttta tttaacttat      420

taactgtaga ggcttccgaa accttcaaga taaaggcaat ggtacagtac ttttgtgtaa      480

tgtgtaattg ttaccacttt tccttgctat ctagtggaga agtgtcacgc tcaa            534


<210>  4390
<211>  64
<212>  DNA
<213>  homo sapiens

<400>  4390
tcctctccaa aggaaagcga ggtggacatt catctgtttc cactgagtct gagtcttcaa       60

gttt                                                                    64


<210>  4391
<211>  166
<212>  DNA
<213>  homo sapiens

<400>  4391
aagacaaaac aggtttgcct tggcatcaga gagcacaaag attaaaagtt actttaaatt       60

tgccaatatt ttgggagaac aataaaacta cattttttcc tcttccatac tggtagatgc      120

gaaatttatc tgtgcatgaa agggtcactt ctgtaatagt gcaaca                     166


<210>  4392
<211>  400
<212>  DNA
<213>  homo sapiens

<400>  4392
gcttttgagg ataatgttac tagactttat gccatggtgc tttcagttta atgctgtgtc       60

tctgtcagat aaactctcaa ataattaaaa aggactgtat tgttgaacag agggacaatt      120

gttttacttt tctttggtta attttgtttt ggccagagat gaattttaca ttggaagaat      180

aacaaaataa gatttgttgt ccattgttca ttgttattgg tatgtacctt attacaaaaa      240

aaatgatgaa aacatattta tactacaagg tgacttaaca actataaatg tagtttatgt      300

gttataatcg aatgtcacgt ttttgagaag atagtcatat aagttatatt gcaaaaggga      360

tttgtattaa tttaagacta tttttgtaaa gctctactgt                            400


<210>  4393
<211>  369
<212>  DNA
<213>  homo sapiens

<400>  4393
cccagcgcgc cgaggatgtg agtcctgctc gcctctggcg gagcagcagc cactcgcgcg       60

cggagccgga gcgcagcgca gcgcagccgc gggcgctctc cgggccgctc gcgcgagtgc      120

cgcgctcttg ccctagcggc gtcccccggc ctctcgccgg cgccaccgcc gcagcagccc      180

gcgggccgtc cccggccggc cgcccccggc cccagcgccg ctgaccctgt ccgccgcggg      240

cggggacgcg ggcggaggag gcgccgcggc ggagcccccg gacgcgacca tgtcggaggt      300

gctgccctac ggcgacgaga agctgagccc ctacggcgac ggcggcgacg tgggccagat      360

cttctcctg                                                              369


<210>  4394
<211>  550
<212>  DNA
<213>  homo sapiens

<400>  4394
aatgcagtag ccagcacgtt cgaggcggtt tccaggaaga gtgtgcttgt catctgccac       60

tttcgggagg gtggatccac tgtgcaggag tggccgggga agctggcagc actcagtgag      120

gccgcccggc acacaaggca cgtttggcat ttctctttga gagagtttat cattgggaga      180

agccgcgggg acagaactga acgtcctgca gcttcggggc aagtgagaca atcacagctc      240

ctcgctgcgt ctccatcaac actgcgccgg gtaccatgga cggccccgtc agccacacct      300

gtcagcccaa gcagagtgat tcaggggctc cccgggggca gacacctgtg caccccatga      360

gtagtgccca cttgaggctg gcactcccct gacctcacct ttgcaaagtt acagatgcac      420

cccaacattg agatgtgttt ttaatgttaa aatattgatt tctacgttat gaaaacagat      480

gcccccgtga atgcttacct gtgagataac cacaaccagg aagaacaaat ctgggcattg      540

agcaagctat                                                             550


<210>  4395
<211>  47
<212>  DNA
<213>  homo sapiens

<400>  4395
caggaatcca agcgctttgt gcagtggcag tcgtctatct gagcccc                     47


<210>  4396
<211>  493
<212>  DNA
<213>  homo sapiens

<400>  4396
catgttgtca gtggccaagg ctacacagaa ggctccctgc tgcccggagc aggtacatcc       60

accagagcaa agggaaccac ttttattttg catgagtttg gtaactgatt actctcccct      120

caaagaaaag acattcaggt gtttctcaac gacatcttct gtccagcaag ctcggtttga      180

atacgtcact taccagtgcc attgcaggac ccaaattcac agttcataaa agatgtgacc      240

actacatgta aaaatagcat tctacttgat cttacagtat gtatgtatgt atgtatggag      300

acatatgtgt gcgtgtggat gtctacatgg ttaatggaaa gcactgtgct ctgaagtgga      360

tcagtctcaa gtgtctggta acagcagcag tgcttagaaa attcttttgt tgaaaagagt      420

tactgttatt atcagaattt gccaacctaa agaatgaatt tttaaattca taacttggtc      480

atgttcacaa caa                                                         493


<210>  4397
<211>  518
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (428)..(428)
<223>  n is a, c, g, or t

<400>  4397
cctgatggct ttaggcagcg ttgcagtcac caaggatgat ggctgctatc ggggagagcc       60

atcctggttt cacaggaaag cccagcagaa tcggagaggc ttttccgagg agcagcttcg      120

ccagggacag aacgtaatag gcctgcagat gggcagcaac aagggagcct cccaggcggg      180

catgacaggg tacgggatgc ccaggcagat catgttagga cgcggcatcc tgcccctggt      240

agagaggacg aatgttccac accatggtct ctacgaaaaa gaaatagtta gtcaccttct      300

gaccttctcc tctttctcaa agccttctgt ccctggtttt tgcaagtgct gcatttccgc      360

cgagaatccg cgttgcctac tgctgccacc tcctgttcat ttagaactat gcaaagactc      420

cgcttccntt ttcctgagct cctcgggccc cagagtctct gtttgattat ttatttattt      480

atttatttat ttgccaaaaa ttctcctctt caacttat                              518


<210>  4398
<211>  438
<212>  DNA
<213>  homo sapiens

<400>  4398
caagattgtc ttacaagtcg tgctggctaa tttttagttt gtattcataa gtggttttta       60

aaagcctttt ttaaagtgta atttgcatgt tctactttga ttgtatgtaa acatatttta      120

gaacaaaaaa tgtatttgta ttttattgaa tatagaggca agaaaattgt acattgtttg      180

aaatgttctt tttgtaacag tttttattca taaagcattt ttgtacattt aaaatgaaca      240

tggacttgct gttatttgag gcgtagatac atctagcatg cttactgtca tgctcctcca      300

tggtcttaga tgttgggttt taaacatttt tttctaaaag aaagctcagt cttttccgct      360

accagatcag gttagcacag tatagagcac ttaactatta aaaaaaaaaa gttaatccta      420

ttcatatgtt attcattg                                                    438


<210>  4399
<211>  356
<212>  DNA
<213>  homo sapiens

<400>  4399
ggacagcaat agcagcaacg acattaacaa gcgggagatg aagcccttca agcgctacgt       60

gaagaagaaa gccaagccca agaaatgtgc ccggcgtttc accgactact gtgacctgaa      120

caaagacaag gtcatttcac tgcctgagct gaagggctgc ctgggtgtta gcaaagaagt      180

aggacgcctc gtctaaggag cagaaaaccc aagggcaggt ggagagtcca gggaggcagg      240

atggatcacc agacacctaa ccttcagcgt tgcccatggc cctgccacat cccgtgtaac      300

ataagtggtg cccaccatgt ttgcactttt aataactctt acttgcgtgt tttgtt          356


<210>  4400
<211>  509
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (261)..(261)
<223>  n is a, c, g, or t

<400>  4400
tagatgaggg ctatcgactg ccacccccca tggactgccc agctgccttg tatcagctga       60

tgctggactg ctggcagaaa gacaggaaca acagacccaa gtttgagcag attgttagta      120

ttctggacaa gcttatccgg aatcccggca gcctgaagat catcaccagt gcagccgcaa      180

ggccatcaaa ccttcttctg gaccaaagca atgtggatat cactaccttc cgcacaacag      240

gtgactggct taatggtgtc nggacagcac actgcaagga aatcttcacg ggtgtggagt      300

acagttcttg tgacacaata gccaagattt ccacagatga catgaaaaag gttggtgtca      360

ccgtggttgg gccacagaag aagatcatca gtagcattaa agctctagaa acgcaatcaa      420

agaatggccc agttcccgtg taaagcacgg gacggaagtg cttctggacg gaagtggtgg      480

ctgtggaagg cgtagcatca tcctgcaga                                        509


<210>  4401
<211>  69
<212>  DNA
<213>  homo sapiens

<400>  4401
acaggaatac gatgaagccg ggccttccat tgtccaccgc aaatgcttct aaaacacttt       60

cctgctcct                                                               69


<210>  4402
<211>  239
<212>  DNA
<213>  homo sapiens

<400>  4402
gcagtggccc catccagcat gtgtgtgtct ctatcttgca tctacctgct ccttggccta       60

gtcagatgga tgtagataca gatccgcatg tgtctgtatt catacagcac tacttactta      120

gagatgctac tgtcagtgtc ctcagggctc taccaagaca taatgcactg gggtaccaca      180

tggtccattt catgtgatct attactctga cataaaccca tctgtaatat attgccagt       239


<210>  4403
<211>  303
<212>  DNA
<213>  homo sapiens

<400>  4403
gtgcccggcc tctggttttg ttttgttttt tttttttaat gggggacaaa agagagggaa       60

agacccctat aaatctatat ataacaatgt aaccatatac ttgcatgtct aatacaaact      120

gaagaaatta gcctaactgc caatatcaag ttgcagattt taatccatgg aaattgtgtt      180

ttgtgctgaa ttgtatttgc tgattacctg aaattggctt ctttttattg ggcttctctg      240

gagaatttct cccactcccc acctctgcag aagaaaattt tgctcttata aaacctcatg      300

ttt                                                                    303


<210>  4404
<211>  286
<212>  DNA
<213>  homo sapiens

<400>  4404
gagtagaggt ctccggctat tccagaaaga aaagtgagcc acatgcaggc tgatgaatgc       60

cgacacttcc agaatgtata gaaatagtcc ctgtcctggc ctgccactga ccctgtctgt      120

attttctcgg aggttgtttt tctccttctc cttcccagga aggtctttgt atgtcgaatc      180

cagtgcactc aagtttggcc aagggactcc acagcaccca gaagactgca tgcctcaagg      240

tttatgtcac tcctctgctg ggctgttcat tgtcattgct gtgttc                     286


<210>  4405
<211>  237
<212>  DNA
<213>  homo sapiens

<400>  4405
attgctggcc tgttgtaggt ggtagggaca cagatgaccg acctggtcac tcctcctgcc       60

aacattcagt ctggtatgtg aggcgtgcgt gaagcaagaa ctcctggagc tacagggaca      120

gggagccatc attcctgcct gggaatcctg gaagacttcc tgcaggagtc agcgttcaat      180

cttgaccttg aagatgggaa ggatgttctt tttacgtacc aattcttttg tcttttg         237


<210>  4406
<211>  276
<212>  DNA
<213>  homo sapiens

<400>  4406
atgtacttca tctggttggg ctggattccc tctgataagc cttcccagtt gactgaaaga       60

tgaggctagg ctctagcaag ttgaagtcaa accagctcct tcaagaagct ttgagcagaa      120

tgaagtgggg aggacccagc ttccagccca ggaagcccac tgtacctgga gccatctggg      180

ataagacttt gacccatgac tcccatatcc acagcctgtc catcctagcc catcccagtt      240

tatcctgtat catttgagct gggattccca catcct                                276


<210>  4407
<211>  236
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (67)..(67)
<223>  n is a, c, g, or t

<400>  4407
agcactggga acaacccgtc tacacacagc tcactcgacc ttgaggaggc ctcccacgaa       60

gggcgangat ggccgagatg atcctaaaaa taaccgaaga aagagaggac caaccagaat      120

tccctttgga catttgtgtt tttttgtttt tttattttgt tttgtttttt cttcttcttc      180

ttcttcctta aagacattta agctaaaggc aactcgtacc caaatttcca agacac          236


<210>  4408
<211>  498
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (161)..(161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (163)..(164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (167)..(170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (184)..(199)
<223>  n is a, c, g, or t

<400>  4408
tggatttacc tgctgagttc cagcagcgtg atgggctgac atcccaccta caagtatgac       60

acctgtgtaa caccagctag gtacggctgg agaaggctga agagagaatg ccattaaatg      120

gaagaatgta ctgattgtag tgaccttctc cacacacaca nanncannnn cacacacaca      180

cacnnnnnnn nnnnnnnnnc tacagtaata cagcaagcgt ggaataatca gccaatatat      240

aacattccat cagtatttta ttaaggaaat aacctgaatg tggttgattt tgacatagct      300

gcaattacag ttttcttcta tttttcaagc cacaataagg aaaataaact actcatggtc      360

taaatactag agataaagta gattcatggc ttggtaagga aattttaagc attccttcaa      420

agattgacgt gctaaaataa gcattgatgt tttgagtttt tttacaccta ggatttttag      480

cttgggtgtg taggtgaa                                                    498


<210>  4409
<211>  124
<212>  DNA
<213>  homo sapiens

<400>  4409
caatttggcg cggagtgcaa ataccagttc caggcctggg gagaatgtga cctgaacaca       60

gccctgaaga ccagaactgg aagtctgaag cgagccctgc acaatgccga atgccagaag      120

actg                                                                   124


<210>  4410
<211>  337
<212>  DNA
<213>  homo sapiens

<400>  4410
aaggagattg cctaccaagg acaaaacaat aaatttaaaa atcaaacgat ttctccatac       60

gctcatagtc acatatggaa ttttgagaaa ataaagcatg ctgtctttag gaatttttat      120

acttctttgt ctttcttcct taatatttgc ttctagctgc tcttggcaat gatgaattgt      180

tatgtatgca ttaatgtttt gcagcccaaa agttgttcac atttttccta tataagatct      240

gtggagtgtg tgtttcaaag agagaactac agaaatgtta aagcaggaaa acctgaatgt      300

gatgtgcaca ttttcatccc acatggacaa tgtatgt                               337


<210>  4411
<211>  579
<212>  DNA
<213>  homo sapiens

<400>  4411
tctgggtctt attctcaaca catgaatcat cgctactcct actgtaagag agaagcggaa       60

gaacgtgaca gcacagagca ggaagaggca gggcctgaaa tcctctcgaa tgagcacgtg      120

ggtgccaggg cgtctccctc acagggcgac tcggacgaga gagagagttt gacaagggaa      180

gaggatgaag acagtgaaaa agaggaagag gaggaggata aagagatgga agaattgcag      240

gaagaaaaag aatgtgaaaa accacaaggg gatgaggaag aggaggagga ggaggaagaa      300

gtggaagaag aagaggtaga agaggcagag aatgagggag aagaagcaaa aactgaaggt      360

ctgatgaagg atgacagggc tgaaagtcaa gcaagcagct taggacaaaa agtaggcgag      420

agtagtgagc aagtgtctga agaaaagaca aatgaagcct aatcgttttt ctagaaggaa      480

aataaattct aattgataat gaatttcgtt caatattatc cttgcttttc atggaaacac      540

agtaacctgt atgctgtgat tcctgttcac tactgtgta                             579


<210>  4412
<211>  518
<212>  DNA
<213>  homo sapiens

<400>  4412
cctttatgaa ggtggtttat tacaaataag cacactaacc cctcggaagt tgttttacct       60

actttaaaag ttttaatgga ttgcacctct gtaaactatt cctaaaatgt gtatgatata      120

tttgaaaagg cttccattaa tataatagct ttgcttgcag ccttccaatc tatgttggtt      180

tacctgtagt gttttataaa gtgtggtcag aggcccctat agaatgtatt gtttgaaagt      240

gtagtgatat atttgtgttt ttatttcaag taagtcattt taaccgaatg ttcattcata      300

ttcatttata aaaagtacct gtatcaaagg aattttaaca aagagcaatc agtattattg      360

gaccaaattt ggtgtttgtt ttcaccttga cgctcttctt ttcattattt ctaatgctac      420

aagaatgctg taaagtgtct tctaaaatga tgtagcctga caagacattt ttttcagtgt      480

ataaaactag gtagtattgt gcactgattt gaccattg                              518


<210>  4413
<211>  388
<212>  DNA
<213>  homo sapiens

<400>  4413
gttactacat ttaagctctg attctatata aaatgtcacc aaaaagttga ctttgaattt       60

gttggacttt taaaaaacca gttggaaata taggttgggt ttttttctta ttgttttctc      120

cccagggtta gaaaaattgg tataagttcc taattaaaag ctgaataaac tttgagaaat      180

tatttctgag ttgaccaata aataaaaata ccactttctt taaaaaagcc tagggaattg      240

aagctctgta catatactaa tgatgccttt acaacccagt ccttgataat accagattct      300

cggtgcattg ttcatgtctg tatctgcaag cctgttctgc cattgcagtg tgatgaacct      360

agaggtaact accatgtgaa cttgaact                                         388


<210>  4414
<211>  268
<212>  DNA
<213>  homo sapiens

<400>  4414
gtaatactaa gtcctcagag ctccatgctg ttctgaaagg gatggccaca agttctttcc       60

cagcctcttc cattcccttt cttttcatgc ccatcccgat gaacctgcat cattccccga      120

cactgccaag ccaaccctgg aaaaggagtt cgctggccat tggctagaat cagggtggag      180

aagttccctg aaccttcctg tctcccaggg acatgtatgc ttccagggac aagcttaggt      240

catgaacatg gtcagaacct ttggacaa                                         268


<210>  4415
<211>  169
<212>  DNA
<213>  homo sapiens

<400>  4415
ggagtcgctg gctctgatcc cattacaggc ccctctgaag accatgctgc agattggggt       60

gatgcccatg ctcaatgagc ggacctggcg tggggtgcag atcccactac ctgagggcat      120

caactttgtg catgaggtgg tgacgaacca tgcgggattc ctcaccatc                  169


<210>  4416
<211>  518
<212>  DNA
<213>  homo sapiens

<400>  4416
tgggcgagtt gctttctcca atcagcagag ctatattgct gccattagtg ctcggtttgt       60

tcagcttcag catggtgata ttgataaacg tgtggaggta aagccatatg tgctagatga      120

ccagatgtgt gatgaatgcc agggcgcacg ctgtggtgga aaatttgctc cctttttttg      180

tgccaatgtc acttgcctgc agtattactg tgagttttgt tgggcaaata tccactctcg      240

tgctggacgt gagttccata agccattggt aaaggaaggt gctgatcgcc cacgtcagat      300

ccacttccgc tggaactaag aatagcaaac tggcctctgt ttaacaagga aagaaagggt      360

gcatgtggct tactgtgtct gaagatactg acatgcagaa gaaataagtg cattcttctg      420

cttttcaccc cagctatcaa tacatgcatc tttatcagca gccaaaacac tacaagcctc      480

ttgtttttca ccaaaaccct acatctcagg cttactaa                              518


<210>  4417
<211>  396
<212>  DNA
<213>  homo sapiens

<400>  4417
atgttgttgg tctgatctga ttcttctttg tttgtgggtg gaacggcact gagagaagta       60

tagtttttta aacttgaaca tgttcagtag ttacattgcc ttagaaaacc cagacacata      120

gcagtggaaa tgaaagaaat ggcatcagaa gtgacttaat ttagcaattg tgattcctct      180

tgtaaaacaa aacaaaaaaa caatgccata ttttttggag aaaagttggc aatatagggg      240

tttcgttgtc tgtttcacaa gaagactcat ttgttctttt gggggaacca gtgccttaca      300

gattttgtat atactgtaat tattcaggac tagggaacaa acaattgtat tgtatttgtt      360

acagattgta tatggctttg ttttaacatt ccccta                                396


<210>  4418
<211>  460
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (294)..(294)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (297)..(297)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (304)..(304)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (312)..(312)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (316)..(316)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (318)..(318)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (322)..(322)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (324)..(324)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (327)..(328)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (333)..(335)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (337)..(339)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (342)..(342)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (350)..(350)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (354)..(354)
<223>  n is a, c, g, or t

<400>  4418
aagctttggt acaagctgac ctttctatag cgtgctgcat tggtaaatga aaaaaaatgg       60

ggcaaacgtt ggagtccttt ccttgtaaat tgccagcatc agcttaaaaa ctcctgtatg      120

ttacatatcg taccatttta atctcttcaa ctttctttgt accttctggc tgtatgcttt      180

ctcttttaac tttttatatt gtcattttat attaaatttc tgtgtatata atgtaaaacc      240

acaatttttg aataaaattt agttcctgca gcttgattta aatagaggac tttnacnggc      300

accngcatct cnccanangc angnacnnag agnnncnnnc anacaaaaan aaanacataa      360

aaacaaagca agcaatgcac tattaattat acattttgat gttctatcat taatattgta      420

cagtacattt tggttcacac aattaaatcc actgttttct                            460


<210>  4419
<211>  447
<212>  DNA
<213>  homo sapiens

<400>  4419
tcctgaccac aatccgggat gagccagagg ttccggtgag tggggggccc agtggagact       60

tcgagctgcc agaagaagag accacacaac cagacacagc caatgaggtg gtagctgtgg      120

gaggggctgc ggccaaggca tcatctccac ctgggacact gcccaagggt gcccgcccgg      180

gccctggcct cctggacaat gccatcgact cgggcagctc agctgctcag ctgcctcaga      240

agagtatcct ggagcggaag gaggtgctcg tagctgtgat tgtgggcggg gtggtgggcg      300

ccctctttgc tgccttcttg gtcacactgc tcatctatcg tatgaagaaa aaggatgagg      360

gcagctacac gctggaggaa cccaagcagg cgagcgtcac ataccagaag cctgacaagc      420

aggaggagtt ctatgcctag tggagcc                                          447


<210>  4420
<211>  204
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (55)..(55)
<223>  n is a, c, g, or t

<400>  4420
gtgtagctat cctcctgacg agcaacccgt ctgcgtacct aagtgtggct ccccngtggg       60

tcagcgtcct ggtagcatgg atccagtctg aaaggtgagg acaacgtgga aactcatgag      120

ctgagcctgc ccgctgggac acgtctcctt cccgcgtcac cttctggttt agggagccgt      180

caggtcccta aacgttccct acaa                                             204


<210>  4421
<211>  507
<212>  DNA
<213>  homo sapiens

<400>  4421
gagctgtagt tattcatcct tctgtacaaa atgaaaagtt tggaaattgt ttgccctgat       60

accttgaaaa agaagccaga atatttattt gcttcatcaa cttcagtgta tatcattttg      120

tgttatttta tacgaaaaca tgtttattat tttcattttt gtaaaaggaa gtaaaaggtc      180

aacattttct ctcatgtacc aaccttgttt gtatttctat tttctgtaat gtttaagtat      240

gatgttgaag aaattcacat tctcttatag tttggatggg aagactattg actatttcag      300

aaacagactt atttcagagg cttattgttt tctctgtatt tacctaatat tttataactt      360

ttatgaatca gaataatgtc cttcataaat ttgtttaatt gaagtcatct acttctaaca      420

ggacagatac acaactattt gaggtttaca aattacatct ttgataaggg aaatggtttc      480

gtgacatgta cacagttgct attaaaa                                          507


<210>  4422
<211>  201
<212>  DNA
<213>  homo sapiens

<400>  4422
gattgtagaa actcagcaga agctggtaaa aacatgggga gcccggagga caggctgctg       60

tccagggcag aggccatgaa gaagtgcttc cgtggccgac agtctggaaa tgaatccatc      120

atacattagt gccatagagt ttagtaaccg tccagcaagt gtcatcactt ttacagaaaa      180

caaggtccag taatagcaag t                                                201


<210>  4423
<211>  340
<212>  DNA
<213>  homo sapiens

<400>  4423
acggagtacg agatcttcaa aatggaacag gatgcccggg ggcgctatct gctgttcaac       60

ggtcagaggc ccagcgacgg gtccagccca gacaggccag agaagagagc cacgtcctac      120

cagatgccct tggtccagtg tgcctcctct tcgccgaggg cagaggacct cgcagaagac      180

agtggaagca gcctgtatgg ccgggcccct gggaggcaca cctggtccct gctgctggct      240

gcacttgcct gccttgtccc tctgctgcat tggaacatcc gcagatagaa gttttagaaa      300

gttctatttt tccaaaccag gattccttac tattgacaga                            340


<210>  4424
<211>  487
<212>  DNA
<213>  homo sapiens

<400>  4424
gatgtgtcag cctgcgaggt gttccgcttc tacaagctgg tgactctcaa gggcctgatc       60

gagcccatct ccatgatcgt gccccggagg tcagattcct accaggaaga catttaccca      120

atgacaccag gcacggagcc agcactgacc ccggatgaat ggctgggagg catcaaccga      180

gatcccgtgc tgatgtcttt gaaagaaggc tataagaagt cctcaaaaat ggtatttaag      240

gctcccatca aagaaaagaa gagtgttgtg gtcaacggaa tagatttatt agaaaatgtc      300

ccacccagga cagagaatga gctccttcga atgttcttcc ggcagcagga tgagattcga      360

cggttgaaag aggagctggc ccagaaggac atccgcattc ggcagctcca gctggaactg      420

aaaaacttgc gcaacagccc caagaactgt tagctcccca gctgggctgt tttctaagcc      480

gatctct                                                                487


<210>  4425
<211>  349
<212>  DNA
<213>  homo sapiens

<400>  4425
agttcgccca atttaagccc agtagtgtca gttttcctaa tctcagtcca ggtaggaatt       60

aagaaatatc tcaagtgttg atgctatcca agcatgttgg ggtggaaggg aattggtgcc      120

cagaaaatgg gactggagtg aggaatatct tttcttttga gagtaccccc agtttatttc      180

tactgtgctt tattgctact gttctttatt gtgaatgttg taacatttta aaaatgtttt      240

gccatagctt tttaggactt ggtgttaaag gagccagtgg tctctctggg tgggtactat      300

aatgagttat tgtgacccac agctgtgtgg gaccacatca cttgttaat                  349


<210>  4426
<211>  467
<212>  DNA
<213>  homo sapiens

<400>  4426
tgaagacatt ttaccctacc tactctagaa atatacaaca atgttatatt ttacactcct       60

tggaaacatt tgaggaaaaa aatgcaattt gcacttcact ttgttggaat atcccatagc      120

actcaataaa ctcagctgct agagtgccga tgtcaggagg gctgtgtcgg gtaatgcgtg      180

tggctgaatg ggcataacca ctgtggcttc ttgtgctgca gaagctcgtt gacaagactg      240

aggaggattt caagagcaac caagtaaagt catgcatttt ctaattttgt gtatatggaa      300

tatattttta aatagagatt tttctacttt agataatgtg ttaatattgc tattacctag      360

gttaagcact attgtctgtg ctagtaagaa aaagaaagga aaaccatcat tgctttatag      420

tagcttatat caatttagat ttcatcatta ctattttgca tactgga                    467


<210>  4427
<211>  488
<212>  DNA
<213>  homo sapiens

<400>  4427
tattatcttt ctccctgtta cttggctggg gaaagagata gaagctgtat aaacaaattc       60

tcttccatgc tcaaagcaag tgttccatgt gcacaacctg ctgcagactg gggcccttct      120

cagttaattg ggtttcacaa gcaataattt ctccacaaca aaaaccacaa cttgaagtga      180

gttgaaaaga gatcaatagt ggaaacagtc gcctcagtac tttttctttc tggatttcat      240

ctctagaaat ttgaagtgtt tgagacagag tccacccttt gtgcaaggcg agaaccaatg      300

aatggactcc ttgtgtgaat tattgcatct tcttccaaag caggttcatc aagactttca      360

cagagattca tttttgttga gaagtaaggg ttaataggag gatagaattt ggatccaaat      420

ctagtgataa aagtgtccaa gcaatcaaaa agtaagatat tttagggaca taccaacatc      480

ttcccttt                                                               488


<210>  4428
<211>  505
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (32)..(32)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (88)..(88)
<223>  n is a, c, g, or t

<400>  4428
aagtgactcc agacattagg tccagacatt angttaaaaa tagaaagagg aataaagaca       60

tctcttctct ctagaaaaga taacaccnca attaataatc cttcccactt tcattgagat      120

cagcttgtct gataacctga tatgagtgtg ataatgataa acatgataat agtggtactt      180

ttgtaatttt gctggtgcat ttaagaagat agtaaatgat gagttcatct tttcttcgaa      240

cattcctatt cctagatgta gtttacctca aattgggaat tataactgtc taatttttgt      300

tgtgtacctg atgccccttt tgctttaata ccacagtgta acaattaaat atcacactat      360

gacatatgat ttaagtagga tattttaaag ataaatttta ggggtaaatg tttacttcaa      420

aatgactcca tatttcaaat atctgtttag actgtgaagg ccaaataatt tttaagaaaa      480

catttgaaga gtagtgtgtt tgcat                                            505


<210>  4429
<211>  378
<212>  DNA
<213>  homo sapiens

<400>  4429
tacgattatt attcagcagc acattctgag gggggaacaa ttcacaccac caataataac       60

ctggtaagat ttcaggaggt aaagaaggtg gaataattga cggggagata gcgcctgaaa      120

taaacaaaat atgggcatgc atgctaaagg gaaaatgtgt gcaggtctac tgcattaaat      180

cctgtgtgct cctcttttgg atttacagaa atgtgtcaaa tgtaaatctt tcaaagccat      240

ttaaaaatat tcactttagt tctctgtgaa gaagaggaga aaagcaatcc tcctgattgt      300

attgttttaa actttaagaa tttatcaaaa tgccggtact taggacctaa atttatctat      360

gtctgtcata cgctaaaa                                                    378


<210>  4430
<211>  526
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (420)..(420)
<223>  n is a, c, g, or t

<400>  4430
aggaccttga tgttgcttgc caccttttgt tttcgtactc tcacagactg cttgaggaag       60

gatgtcagcc caatcagcgg gccctgcaga gttactgatg ttctttcaga aggcaggact      120

gaatggcaga gctagctttg caggaatcat tacagttgct cctttttctc tctggttttc      180

ctggactatg tgaccaggag gactgtcttt tcaaagggaa tttagagcct cactctcctg      240

gatacctgtt acttcctggc tgtcaaccct taaaggaccc cagtgaaatg atgtgcatat      300

gaaaatgtag tttggggatg actctacctg aaaactccaa acagggaaaa agacctcaat      360

tacgagaggc atagtgacct gcctcaccta atcctcaccc ttgctgctcc tgatgcaaan      420

ccaggcacaa caagggaaat ccatgtccaa agcatagtgt ggtctcaact cttagaaact      480

ccctgggttt cccttttctc ttagccacat gctaaccagt tgcttc                     526


<210>  4431
<211>  365
<212>  DNA
<213>  homo sapiens

<400>  4431
gactcaacag ccacgacccg cactcggacg aggacacgcc gacgtcggac gacctggagc       60

agttcgccaa gcagttcaag cagcggcgca tcaagctggg cttcacgcag gccgacgtgg      120

ggttggcgct gggcacactc tacggcaacg tgttctcgca gaccaccatc tgccgcttcg      180

aggccctgca gctgagcttc aagaacatgt gcaagctcaa gccgctgctg aacaagtggc      240

tggaggaggc ggactcaagc accggcagcc ccacaagcat cgacaagatc gcggcgcagg      300

gccgcaagcg caagaagcgg acctctatcg aggtgagcgt caagggcgcg ctggagagcc      360

acttc                                                                  365


<210>  4432
<211>  447
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (109)..(109)
<223>  n is a, c, g, or t

<400>  4432
tcaacgacgg gaaaagctac acaaggtggc tccaaaaatc aaagccctga tgatggagtc       60

aggtacgacc atggttggct accagcccca aggggacaag gccaacttnc ttccggatgg      120

tcatctccaa cccagccgct acccagtctg acattgactt cctcattgag gagatagaaa      180

gactgggcca ggatctgtaa tcattccttc gcagaaccat gagctttatg ggaatggcct      240

tttccctctg gcacttccag aacaaacctc tatatgttgc tgaaacacac aggccatttc      300

attgagggaa aacataatat cttgaagaat attgttaaaa ccttacttaa agcttgtttg      360

ttctagttag caggaaatag tgttcttttt aaaaagttgc acattaggaa cagagtatat      420

atgtacagtt atacatacct ctctcta                                          447


<210>  4433
<211>  485
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (227)..(227)
<223>  n is a, c, g, or t

<400>  4433
aaaggcggca cacttcacta cagacactct attaagatac atttgcgctg acctttgctt       60

tcacgccatt taatactgtc actgcgctct ccagtatata cttcctttct agaacccgac      120

ttgcccacgt ttaggggttc actctgcacc ctgatgtggg aggctttggc gcaggggaca      180

ctttcaggaa agggaggagc acaaggactc tgtgcatctt gactgcnccc caaagaggct      240

ccaggatcag gagtgaaaga ttttaaagca gcctccgaag cttaacaaat gagcattcca      300

agctcagttt tgtgcaaatc gcctttctga ctcttgagta ggatggaggc ttaaatttaa      360

tggcgacttg gggggaaggg agccaccctg ggggagtctg aggagttcag actgtgccct      420

tgggaatttc cactctggct ttccgtgcca ctcttcttcc tttccatccc aaaagtctct      480

tgcgg                                                                  485


<210>  4434
<211>  516
<212>  DNA
<213>  homo sapiens

<400>  4434
gacatgcgaa agtttgcctt tgtaccatat aaagggggag ggaaatagct aataatgtta       60

accaaggaaa tatattttac catacattta aagttttggc caccacatgt atcacgggtc      120

acttgaaatt ctttcagcta tcagtaggct aatgtcaaaa ttgtttaaaa attcttgaaa      180

gaattttcct gagacaaatt ttaacttctt gtctatagtt gtcagtatta ttctactata      240

ctgtacatga aagtagcagt gtgaagtaca ataattcata ttcttcatat ccttcttaca      300

cgactaagtt gaattagtaa agttagatta aataaaactt aaatctcact ctaggagttc      360

agtggagagg ttagagccag ccacacttga acctaatacc ctgcccttga catctggaaa      420

cctctacata tttatataac gtgatacatt tggataaaca acattgagat tatgatgaaa      480

acctacatat tccatgtttg gaagaccctt ggaaga                                516


<210>  4435
<211>  510
<212>  DNA
<213>  homo sapiens

<400>  4435
gatggcgacc tggtcacact aggcaccacc atcggccgca aggtgctaga gagcggggtg       60

aacgtgaccg tgtcccagcc cacgctgctg gtcaacggca ggactcgaag gttcacgaac      120

attgagttcc agtactccac gctgctgctc agcatccgct atggcctcac ccccgacacc      180

ctggacgaag agaaggcccg cgtcctggac caggcgagac agagggccct gggcacggcc      240

tgggccaagg agcagcagaa agccagggac gggagagagg ggagccgcct gtggactgag      300

ggcgagaagc agcagcttct gagcaccggg cgcgtgcaag ggtacgaggg atattacgtg      360

cttcccgtgg agcaataccc agagcttgca gacagtagca gcaacatcca gtttttaaga      420

cagaatgaga tgggaaagag gtaacaaaat aatctgctgc cattccttgt ctgaatggct      480

cagcaggagt aactgttatc tcctctccta                                       510


<210>  4436
<211>  532
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (373)..(374)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (385)..(385)
<223>  n is a, c, g, or t

<400>  4436
cctccaggta aagcctagag gccaaagaac tttccaggtc agccggacag ctccagcagc       60

tccacgttcc aggcagcctc gcccgccggc tgcgctccca gcactggggt ttggggggag      120

gggggtggcc aaggggcgtt tcctctgctt ttggtgtttg tacatgttaa gaattgacca      180

gtgaagccat cctatttgtt tccggggaac aatgacgggg tgggagaggg gagaggagag      240

agtttgggaa agggagatgg agaagaactc aaggacattg caaccctgcc cggcgcagat      300

ctgattttca catctctacc tggacattga gcctccaggc accatgttga ggagagatga      360

aaaccagggc ggnngaactt caggntgaag gacagagtcc tgggtggggc agcggctgca      420

gggcgcacca gagaacccag ccagaggggt tgtgagtacc agtggtgttg cttccaccct      480

gcagcaggtg ggatgaggtc tgtgtgtgtg tgtgaaccat cattttttga tc              532


<210>  4437
<211>  428
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (304)..(304)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (306)..(306)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (319)..(319)
<223>  n is a, c, g, or t

<400>  4437
gaagacggcg tgctatgaca ttgacgtgga ggtggaggag ccattaaagg ggcagatgag       60

cagcttcctc ctatccacgg ccaaccagca ggagatcggt gctctggaca gtaagatcca      120

tgagacgatt gagtccataa accagctcaa gatccagagg gacttcatgc taagcttctc      180

cagagacccc aaaggctatg tccaagacct gctccgctcc cagagccggg acctcaaggt      240

gatgacagat gtagccggca accctgaaga ggagcgccgg gctgagttct accaccagcc      300

ctgntnccag gaggccgtna gtcgctactt ctactgcaag atccagcagc gcaggcagga      360

gctggagcag tcgctggttg tgcgcaacac ctaggagccc aaaaataagc agcacgacgg      420

aactttca                                                               428


<210>  4438
<211>  153
<212>  DNA
<213>  homo sapiens

<400>  4438
ttgaatgaac ctgcaaagca tcctgcagcg tgagcagctc ctccacctgg agctccgaag       60

catcttctca ggccaaagcg gcattacccg tgaatctgtc ttctccgcca cagcatggtt      120

tgaggcgcag tctgttaata tagctgggcc atg                                   153


<210>  4439
<211>  360
<212>  DNA
<213>  homo sapiens

<400>  4439
agccgttgcc aaggtgaaat gtgaggccag gtcagccttg accaagccga agaataacca       60

taactgtaaa aaagtctcaa atgaagaaaa accaaaggtt gccattggtg aagagtgcag      120

ggcagatgaa caagccttct tggtggcact ttataaatac atgaaagaaa ggaaaacgcc      180

gatagaacga ataccctatt taggttttaa acagattaac ctttggacta tgtttcaagc      240

tgctcaaaaa ctgggaggat atgaaacaat aacagcccgc cgtcagtgga aacatattta      300

tgatgaatta ggcggtaatc ctgggagcac cagcgctgcc acttgtaccc gcagacatta      360


<210>  4440
<211>  89
<212>  DNA
<213>  homo sapiens

<400>  4440
aaaacaagtg ggacatattt tcctgagagc agcacaggaa tcttcttctt ggcagctgca       60

gtctgtcagg atgagatatc agattaggt                                         89


<210>  4441
<211>  388
<212>  DNA
<213>  homo sapiens

<400>  4441
tccgtctgcc cagcaaagtt tgaccaaatc gagcagttca acgaccacat gaggatgcat       60

gtgtctgacg gataagtagt atctttctct ctttcttatg aacaaaacaa aacaacaaca      120

aaaaacaaac aaacaaaaaa gctatggcac tagaatttaa gaaatgtttt ggtttcattt      180

ttactttctg tttttgtttt tgtttcgttt cattttgtac tacatgaaga actgtttttt      240

gcctgctggt acattacatt tccggaggct tgggtgaata atagttttcc cagtctccct      300

cggatggtgg ccttaaggcc tggtagtgct tcaagaggtc cactggttgg atctctagct      360

actggcctct aaatacaacc cttcttta                                         388


<210>  4442
<211>  425
<212>  DNA
<213>  homo sapiens

<400>  4442
ggaaggtctc tccttcaaca agctggtcct cagcctgcca gtgaatgtga gatgttccaa       60

gacagacaat gctgagtggt cgattcaagg aatgacagca ttacctccag atatagaaag      120

accctataaa gcagaacctt tggtgtgtgg cacgtcttct tcctcttccc tgcacagaga      180

tttctccatc aacttgcttg tttgccttct gctactcagc tgcacgctga gcaccaagag      240

cttgtgatca aaattctgtt ggacttgaca atgttttcta tgatctgaac ctgtcatttg      300

aagtacaggt taaagactgt gtccactttg ggcatgaaga gtgtggagac ttttcttccc      360

cattttccct ccctcctttt tcctttccat gttacatgag agacatcaat caggttctct      420

tctct                                                                  425


<210>  4443
<211>  521
<212>  DNA
<213>  homo sapiens

<400>  4443
gatagtgatg ttctgttcta aactgttctg ttttagtgaa ggtagatttt tataaaacaa       60

gcatggggat tcttttctaa ggtaatatta atgagaaggg aaaaaagtat ctttaacagc      120

tctttgttga agcctgtggt agcacattat gtttataatt gcacatgtgc acataatcta      180

ttatgatcca atgcaaatac agctccaaaa atattaaatg tatatatatt ttaaaatgcc      240

tgaggaaata catttttctt aataaactga agagtctcag tatggctatt aaaataatta      300

ttagcctcct gttgtgtggc tgcaaaacat cacaaagtga ccggtcttga gacctgtgaa      360

ctgctgccct gtttagtaaa taaaattaat gcatttctag agggggaata tctgccatcc      420

agtggtggaa atgtggagta aagaagctgg tggtctgctt ctgtgctgta tgccagcctt      480

ttgccttaag ttgagaggag gtcaacttta gctactgtct t                          521


<210>  4444
<211>  491
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (312)..(312)
<223>  n is a, c, g, or t

<400>  4444
gatgcaccca gatggtacca ttgatgggac caaggacgaa aacagcgact acactctctt       60

caatctaatt cccgtgggcc tgcgtgtagt ggccatccaa ggagtgaagg ctagcctcta      120

tgtggccatg aatggtgaag gctatctcta cagttcagat gttttcactc cagaatgcaa      180

attcaaggaa tctgtgtttg aaaactacta tgtgatctat tcttccacac tgtaccgcca      240

gcaagaatca ggccgagctt ggtttctggg actcaataaa gaaggtcaaa ttatgaaggg      300

gaacagagtg anagaaaacc aagccctcat cacattttgt accgaaacct attgaagtgt      360

gtatgtacag agaaccatcg ctacatgaaa ttggagaaaa acaagggcgt tcaaggaaaa      420

gttctggaac accaaccatg aatggaggca aagttgtgaa tcaagattca acatagctga      480

gaactctccc c                                                           491


<210>  4445
<211>  421
<212>  DNA
<213>  homo sapiens

<400>  4445
acattagcta cttcattatg gtttcttgaa cttctgaaaa aaattagaaa tgtattaaac       60

ttatcagtaa cataaaaact tattttgttt cacctaacga atactgcgtt tgtaaaaata      120

aatttaatat agaatatatt tttaaattaa atatttgaat ataaaatagc tctaagaaag      180

aagcaaatta tcactgaaca tatttcttat tatttctggc tttgaattat acgtaactta      240

aattgtctta aatgatacag aatattggag aatatgatac tttcacataa tatactatga      300

acctgttcat ataactctga ttgactacta acttctgttt tatgtattta ttaaagagct      360

gacactgtag tttgtggtga gatgtttatt tttctaacag agcttataac agttaggaca      420

a                                                                      421


<210>  4446
<211>  48
<212>  DNA
<213>  homo sapiens

<400>  4446
gaattatcgt aattaagctc tccaactcgt taagtcagaa tataatat                    48


<210>  4447
<211>  283
<212>  DNA
<213>  homo sapiens

<400>  4447
gggcttgcaa tcatttgaat tgttctgttt cacaataaag gagattcact gggttctgca       60

ttttcaggat tcaatagaac tgctccatta aaaaaataat ccttagcaag cattcgaatc      120

ctaactgctt tgatgcactt gccctcgggc acctgtcatt tccaatatgg taggtgtcaa      180

agtcaaaagt atttactggg agaaaaaaga gaggagtggt tgtagaagtc tccctaaatc      240

agacatgtca agcaatcagc caacgtggtg tatttctcat tca                        283


<210>  4448
<211>  538
<212>  DNA
<213>  homo sapiens

<400>  4448
atggagcatt ctcaagacag tttgtcatgg ctctgttgat tgcaactcct tgtatagctt       60

gtattttgat ttagtttata ttctgcttat tatgtatact gtgttcttat atatgagaaa      120

gcacaaatgc gaaagaggtc atgtcttctc aaaatctagc aaaggaagta gtctgcattg      180

gtgtgcatta cagtattttg cttaatgaaa gcctcagttc tgaatgttga tatgagtagt      240

taaaaggaag tggggccatt ttatgtgttt atctgtgtca agtatttctg gtaataagaa      300

gcacttaatt tacacatatt ttaatcctgt gaaagattcc acatagagaa aagaaagata      360

cctaaccttc aacaaatgtt atttttggaa acacaatttt tgtcattaaa tgttatatta      420

tttcacatat ataaaacaga tgttatgtaa gaatgttgta tattttaaca taaatcattt      480

agagaaatta tctagattca ttaattttca tagtgccttt ttcacatgag tcagctgg        538


<210>  4449
<211>  303
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (88)..(88)
<223>  n is a, c, g, or t

<400>  4449
tggagaatgt tttctctcaa atttcctctg acccatggga atgaaaatac ttaaatactg       60

taaagcatat ctattaataa ttcccccnat tttttaaact aacaaaatgg aatgttaact      120

gaatggaatt aaacatagca attgtcaagc catcaaaatt atatatcgaa ccacttaggc      180

atgttacggg gtaaagtcct cacccctgca tttgagaaat attttattat ttttatttta      240

aggcaaaaca gtgtttactg tgatgggcag aacagccttt tgtatctagg agtccatttg      300

agt                                                                    303


<210>  4450
<211>  294
<212>  DNA
<213>  homo sapiens

<400>  4450
ggaggagcct ttcaacgaac actggcaaac cgtctactca ctctgccatc cctgccacat       60

ccactatgac ctcgtgggca agtacgagac actggaagag gattctaatt acgtcctgca      120

gctggcagga gtgggcagct acctgaagtt ccccacctat gcaaagtcta cgagaactac      180

tgatgaaatg accacagaat tcttccagaa catcagctca gagcaccaaa cgcagctgta      240

cgaagtctac aaactcgatt ttttaatgtt caattactca gtgccaagct acct            294


<210>  4451
<211>  516
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (45)..(45)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (70)..(70)
<223>  n is a, c, g, or t

<400>  4451
ggatttatgg cattgagtat cacactcagc tctgctgtgt taacntttgt gaaactggat       60

ggaacaaacn tttaacttac caagcaccaa gtgtgaaagt gactttcacg gttccttcat      120

aaaactataa taatatccga cactttgata gaaaaaaatt caaagctgtg cctttgagcc      180

tatactatac tgtgtatgtg tggaaataaa aatgtattgt acttttggag aattttttgt      240

aggcattttt ctgtcagatt tgtagtaatt tgtgaggttt gttagagatt aatataggtt      300

ttctttctgt attataaaat gcaccaagca attatggtgg acctattacc ctatgggtaa      360

gaaataaatg gaaatatgac atcggatgtt tcagcaactg ttctgtaaat aaaatctttg      420

atcacaccac tcagtgtgat aattgtgtct acagctaaaa tggaaatagt tttatctgta      480

cagttgtgca agatatgaat ggtttcacac tcaaat                                516


<210>  4452
<211>  431
<212>  DNA
<213>  homo sapiens

<400>  4452
aacccatgag tgctaagagc ctctggaagg gagggcttca ggcccgaagg tctctctggc       60

tctaggaccc ccagtgctca cacaatcaga ccaaggaaca agacccccag gaaggaaaca      120

gatttaagca agaccatggg gtggaaggag aaaggggcta gcactggatg gagctggagg      180

gtcgtagggg agagatctcc aactctctct gtgtccgtgt ggagggctgc agagcctgca      240

gggtgacctg cttccccaaa ggccaacagc attggcctgg ccagaccagg tgaccttaga      300

tttggtgaac aacgtactat ggaagccaca tcactattgg gcccccaggt ctgatctggg      360

ttttgcctct gcccttgggg aaatgctatc agaaattcgc cccattttct ttacagtctt      420

ttgtgtctgt c                                                           431


<210>  4453
<211>  511
<212>  DNA
<213>  homo sapiens

<400>  4453
ggaaaggctg aaccccatag tgcagcccaa aaccactttg acctccagat agactcctgg       60

ggaagcattc accaagccag tggtaacaag atgatgaatg tggaggggga aaagactgct      120

ggaagacttc atctccattc ctgaaacatt ttttttaaaa cagtgtcagg gattatattc      180

gttttactat acaaaaggac atcattgagg aaaagcttgt ttctaggctg tatcacagta      240

aataatcttg attgtttcta gaacaggggt agaaaagtcc caagatcttc agaagggctt      300

ggttttttcc tcccaggatt cttgctcagt gatgagttga aagcacagga taagcttcta      360

agggaggaag gcagcattgg ggagcaggag gctgatggtc ctcctcaggg tctcagtgta      420

aatgataaat tgtctaaaaa taaggaatat tcctgcctct agagaaataa ggtgtacata      480

gttaatgtag catatctggt cgacgttgta t                                     511


<210>  4454
<211>  336
<212>  DNA
<213>  homo sapiens

<400>  4454
tgaaaggcca ggttgtagtc ccagctctta tctgccatct tggacaaagc ttttcccatc       60

tccagtctca gtttcccatc cataaaatgg gggaagtggt aggtcttgct gattgcatcc      120

acattcattc ctccatttcc tttcccagca accccccatt tctgtttggg aattcatatg      180

atctgccaga gcctctccag gggtggaata catgtcctgg actaagccaa tgacaccttc      240

catctttcca gctatggtga ctgggttagg tatgatcttg tgagttaaga caatgaagcc      300

agagggaatt tcaagactta tgggaatgct gggtag                                336


<210>  4455
<211>  346
<212>  DNA
<213>  homo sapiens

<400>  4455
agctcccact ctcagtgggc tgcagttgcc caaccacagg aagaaaggga aggaggtaga       60

gggaagaaac agaagcagtg ttccattttc ttcctcacca atgacattct tttcttttct      120

cctttcgtac tcctccctga gagtcccctc ccttctccca cactcgtttc cctttgctca      180

tgactcctgt agggaagttt cttcaaacaa aacccagctc ctgagtctcc agatgttgtt      240

ctgtcagttg ccaaaggact ttgctgacca ctgcatgggg atccaaccaa ttcaattaat      300

gtcttcatat tgaagaagag atgtaccttc aattgaaaac ctcgtt                     346


<210>  4456
<211>  433
<212>  DNA
<213>  homo sapiens

<400>  4456
ataaccacct tgtgttgcac cttaaaaata tcaagaccat gtaatttcca taacaaaata       60

ggtggcctgg ctatggtatt atagcataca attaggacac tatgcccctg caaaattttg      120

taaatcaaat tcagaggcaa aaacatattt tagaatcata cagtttgcac acgacaagta      180

ggtaataact gtctctaaaa atgttttctc cttagtccgc aatgagctaa gattcagaat      240

agtgtcaaca gcatgctcct atatgaagtt gtttttttta aagcacattt gtttatgaca      300

agcctacatt ctcagtgaat atggcattta gtatttcttt tgaaaacaaa cttaagcatc      360

atgagccaaa gttgcacttt gactcccaac tacggtagca ttatggacat ctcacaatgt      420

caagggtttc tgt                                                         433


<210>  4457
<211>  508
<212>  DNA
<213>  homo sapiens

<400>  4457
tcatacctgt tgtacacttg ggtgaaaagt atggcagtgg gagactaaga tgtattaacc       60

tacctgtgaa tcatatgttg taggaaaagc tgttcccatg tctaacagga cttgaattca      120

aagcatgtca agtggatagt agatctgtgg cgatatgaga gggatgcagt gcctttcccc      180

attcattcct gatggaattg ttatactagg ttaacatttg taattttttt ctagttgtaa      240

tgtgtatgtc tggtaaatag gtattatatt ttggccttac aataccgtaa caatgtttgt      300

cattttgaaa tacttaatgc caagtaacaa tgcatgcttt ggaaatttgg aagatggttt      360

tattctttga gaagcaaata tgtttgcatt aaatgctttg attgttcata tcaagaaatt      420

gattgaacgt tctcaaaccc tgtttacggt acttggtaag agggagccgg tttgggagag      480

accattgcat cgctgtccaa gtgtttct                                         508


<210>  4458
<211>  576
<212>  DNA
<213>  homo sapiens

<400>  4458
aattatctta gcatcttacc tggaatttcc actaaattca ccaatttatg atttgtgaaa       60

tctgatttta ctttttgaaa attttcatgt gaatttccca ttttcagtgt tgtagcacct      120

ctctcttcct ctaagatcct ccaagctcat caaaagccat gatcttatta taccagcagt      180

tttatttatt caatctttca acaagtagtt attgaacttc tataatgtgc caggctctgg      240

agctcgcctt acaccaaaca gacacaatcg atccattcga agtgtcgtaa ttacacattg      300

agggaccaac tagacctttt ctcattgtaa acttggagca aaagtaaatt cattaaaata      360

aatttacatt atagtgccac aaaaaaatga acagaaccag aaagcatttt ttacaaaaat      420

taacagaaca gtgtgataga ggggaaaagg atgtgagatc atggtgccct accttcaata      480

gggtggccag aaaacacctc tctgaagaag cagcatttga gctgagacct gaagaacgag      540

gagtcagtga tgcagagaac ctcaggagat gccttc                                576


<210>  4459
<211>  151
<212>  DNA
<213>  homo sapiens

<400>  4459
ggcgggctca gccattcggc ttggggcacc aggctcccca gagacaatgc tcagtattca       60

ttcatacaca gacgatggaa gaagccactt cttccctggg cggtgtgggt ttcccccagc      120

tcttcccaca cgtgtgttag gaaatgcccg t                                     151


<210>  4460
<211>  397
<212>  DNA
<213>  homo sapiens

<400>  4460
aatttcagtg tcttacagcg gccaaaccat gacgtgaaga atgagatagg agacaggaga       60

tcaccataag cgtccctgat atagcagcac acattttcac gtttccactt aaatcgtttt      120

gcacaaagtc ttgcttcgct cagatgagat gagatatgat ttcctagaga tgtaaaaata      180

agaatgaatg tggcgccccc ttcttccaga tgtaatagaa agctctgccc tatcacaagg      240

ggggtgttga agcgcccctt gtgttttaac tgtatttaac tgagcacaag atgcacaagc      300

tgtggtggga aaccctcagt ttacctttgg agtcttccct gcagatcgca gacctgtttc      360

caggctgatg tttctggtgt gtaattgcta gcgtttc                               397


<210>  4461
<211>  549
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (242)..(242)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (462)..(462)
<223>  n is a, c, g, or t

<400>  4461
ccgactgtgc cacgtggtag gacacatagg acacaggaat tcctgggtcc ttgcccatga       60

ctgtgccatg tggtaggaca caggacacag gaattcctgg aaagtggtgg cttcagaagt      120

gatcttggct cgcaggcacc agtgccacct accaagctgt gaaactaaac cttctccact      180

aaacgtcgtt agggcctcag ttctagacga gtcatacctg attcacctgc actgcttccc      240

cngtgtgctg agcatagagc atacaatagc gcctacttca cggaaacttg tgcctttaaa      300

ctttgtaaac ttaaacacag ccgagaagtt gcttctttgt actttttcta cttttcctac      360

ttttttgtag aaaaaaaaga taatgcctct gcttctattt ctctgggggt gggggtgggg      420

gccgggagcc gtcgcagacc cgtttcatgc agcgtctccc tnggcaccgc gttcggagga      480

cgcaccctca ctcccctgct gccttcactc ctttctgacc aagcaacgct aacttttgta      540

cagatcgat                                                              549


<210>  4462
<211>  457
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (45)..(45)
<223>  n is a, c, g, or t

<400>  4462
gggctacatg tagataccac accaaggctg gaggctggtc tgtcntaaga cagaaagaaa       60

gacgctgggc ccaattttga cttggccagg ggacaccttg gtgtgtttgt tatctttatc      120

tgtgggtagg ctagctgacc catctccttg agtcattccc tttgggaaac cccactgcca      180

gtattgatct cctttttgcc ttgtactgaa tgacacatta cctccacact ctcccggact      240

aggtggtcaa cagggccaca gggttgcttt ctgtctttgg tggggcaggg gagttgacag      300

ggatgagggt ccaaggaata agcatgaatg acaagaaaac aagggaaaga gttaacctgt      360

cacatagcag gttaactttt tcagggtttg cagttagagg tattcgacca ttcactggct      420

gagccagatc acgggaactt gagagctttt actgtga                               457


<210>  4463
<211>  418
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (181)..(181)
<223>  n is a, c, g, or t

<400>  4463
gggtggatct gatgccattg atatatctaa aatgtgggat aaaacttctt taatagctag       60

aaatcaccat aaataagaat gctaaacaga attgaaaatt atatcaactt aaaattttaa      120

gacagcccag aagacattaa tgactctcac ttatgaaatt gtttggcttt tgccactttc      180

ntccttgcct ttgctatatg gtagaatcac agaacttact tagagaataa atatgtctat      240

tgttcaagag taacaggttt aactcatgac caagtgatgt acatccaagt gatgtattct      300

ggaaacgatg gaattttaca gttacagttc cattgagtca aatcccattt tatatataca      360

taaaaattaa gttctgagtg agttctagct aaatataagt gcgactgtaa acgcagcc        418


<210>  4464
<211>  518
<212>  DNA
<213>  homo sapiens

<400>  4464
taatgatggg ttctctcacc actgtcttga tgctctgagc aagttacctc ttccctctga       60

ccctcagttt ccatatttgt aaaatgagaa taaacatacc aacttaataa agatattgtg      120

aggattaatg ggtacagagt gactagaatg atatttgata gaaattaaat ggtagcagta      180

taactattct gatcactgac attaatattc ctattgttat tattctttac tcacgagggt      240

atacaactct tgttttgctg ttgggctgcc ctctttatgt aggtttactg ttaatgctga      300

ggatatactc ggactcaaat gtctcagcag aaggctgaga gacaccaaat gaagtggtca      360

tctagctgaa tgtaggaaaa atgaaatgta gtagcaaatc agtatattct aaggaaattt      420

tcaaggaata ttaatcttca cccaaatttt gaatttttat gtaaaaaatt ataatttaag      480

ggtaaacata gatgacacag ctttcgagtg atttcatt                              518


<210>  4465
<211>  508
<212>  DNA
<213>  homo sapiens

<400>  4465
tcagtagtac gattttgtcc tctcccactg aggaggaggg aagaaggggg aagccagtgg       60

gagttccaca cacgtggtca gtgctgtaag ttcccggata tcagtgtctc tcacatcaac      120

acagaaatag ggcacttctc aacattaatt ttggaattat tcaccattta aaaattgtca      180

ctgctctttt tcattactgt agataactga gagttagctg ttctaggaaa aggccatgtt      240

tcagttagtg ctatgacttc ttttttcgat taaggttgaa gcagtgttct cttagtagcc      300

tgaacacttc tcaaagcgac ttatcactag cggctttaat attgagcttc tatatcgttg      360

tgtccacctc actttttaag gctgttcata cctggcaata ttcacttact ctgctatttt      420

taaaaactat tttaaagttt taagcacaat gttgactctt ctgtaatttc ctaaaattat      480

attgttttcc tacagacagc tcaacttt                                         508


<210>  4466
<211>  438
<212>  DNA
<213>  homo sapiens

<400>  4466
tgcgctgctt ggtgtgaccc acggaggatc cactcccagg atgacgtgct ccgtagctct       60

gctgctgata ctgggtctgc gatgcagcgg cgtgaggcct gggctggttg gagaaggtca      120

caacccttct ctgttggtct gccttctgct gaaagactcg agaaccaagc agggaagctg      180

tcctggaggt ccctggtcgg agaccgacat agaatctgtg acctctgaca actgtgaagc      240

caccctgggc tacagaaacc acagtcttcc cagcaattat tacaattctt gaattccttg      300

gggatttttt actgcccttt caaagcactt aagtgttaga tctaacgtgt tccagtgtct      360

gtctgaggtg acttaaaaaa tcagaacaaa acttctatta tccagagtca tgggagagta      420

caccctttcc aggaataa                                                    438


<210>  4467
<211>  201
<212>  DNA
<213>  homo sapiens

<400>  4467
atttgaatca gtcaggaaca gggttgaatc agtcgaggac gggcatcaac cagccaccat       60

ccctgacgcc cagcaatttt ccttcaccca accaaagttc cagggctttt caaggaactg      120

accacagcag tgacttagct tttgacttcc tcagccaaca aaatgataac atgggccctg      180

ccctaaacag tgatgctgat t                                                201


<210>  4468
<211>  433
<212>  DNA
<213>  homo sapiens

<400>  4468
tgccgtgtcg tctgaggtac ccgttcttat cctagtggtt caggaagaga aaacgcagtt       60

tgcactttca agacagcttc tctaaggctg gcatgttatc tccttgcttt gctttttgcc      120

gttttaaaat gtgtaattgt tccagcattc caatggtctt gtgcatagca ggggactgta      180

accaaaaata aacatgtatt tgtgtaattg gtttgaagaa gtcttgaata gctctttact      240

gtcttacttg gggttgataa gatttgagtg tttgcaattt tttactaaat gtagctccaa      300

agtcttaaat ggcttgtttg ttcttaaact gttaattgat gaaactgtgc ataagtttac      360

aatgtactaa cttattttgc ttattatata tagtgtttta ttggaaattg taaccacaca      420

cttcagcatg atg                                                         433


<210>  4469
<211>  494
<212>  DNA
<213>  homo sapiens

<400>  4469
atgtttggcc tagattgacc catgcctgcc ctcttctcaa cagctgagta gggaaccagc       60

catctgaatg agctgatcgt tgtttatgtt caaatgagta aatgtccaga ccacttaaaa      120

ctacagctgc ttttctggca gtctcgtctg cggggccaaa acttaataaa ccacaggaaa      180

tagactgtca ttcttagttt gctgccaggg cttattttag attgagagca tactggtaca      240

tgagagcagt agtgttgttt gctcttattt tcaaccaggg agctatctgg caccttttgt      300

gctcctggct tttttcaatc atagcactat tgcatctcct agctatttct tttgcccagc      360

agggtaatat tgagtcccat tgcaagtatg gacaaggcct ctggttctcc tcaccaccca      420

ccttttcagc catagaacat cactgaaaat gcctaatgcc tggatctgtg ttctacttta      480

gtttcactgg gaag                                                        494


<210>  4470
<211>  544
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (89)..(89)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (309)..(309)
<223>  n is a, c, g, or t

<400>  4470
ttggtgggag ggctctcaat cagcagggcc ccaggaggga agaagaagtg gggcaaagcc       60

tggcctcgcc gctcgggagc tttgccatnt gagccacgcc tcctccaggc catgctcctt      120

gaacttggaa atgtcaaccg gagcccttac accagccctc cagcatctaa tagacttgaa      180

tctactctaa acgaatattt aatccaacct cactacattg tagctcagtc caacgactaa      240

ccctgaaatg ggggtgttcc agccttcagc gagatggcca agcggtcccc tgggggctgt      300

ggcagcggnc ttatccttct ctgttgccaa ccttgccgtc cgacctcctc cgcccccatg      360

cggtgacccc gtccgtgtct gtgtctgtcc atacgtgtga gtccagctaa aaagacaaaa      420

cagaacccgt gggcccagct cggaaggtgc gtggagaagg ctccgacgtc tccgaagtgc      480

agcccttggg atggcattcc gttgtgtgcc ttattcctgg agaatctgta tacggctcgc      540

ctat                                                                   544


<210>  4471
<211>  487
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (306)..(306)
<223>  n is a, c, g, or t

<400>  4471
cacggcttgt ggcattggca tacttgccct ttacaggtgg agtatcttcg tcacacatct       60

aaatgagaaa tcagtgacaa caagtctttg aaatggtgct atggatttac cattccttat      120

tatcactaat catctaaaca actcactgga aatccaatta acaattttac aacataagat      180

agaatggaga cctgaataat tctgtgtaat ataaatggtt tataactgct tttgtaccta      240

gctaggctgc tattattact ataatgagta aatcataaag ccttcatcac tcccacattt      300

ttcttnacgg tcggagcatc agaacaagcg tctagactcc ttgggaccgt gagttcctag      360

agcttggctg ggtctaggct gttctgtgcc tccaaggact gtctggcaat gacttgtatt      420

ggccaccaac tgtagatgta tatatggtgc ccttctgatg ctaagactcc agaccttttg      480

tttttgc                                                                487


<210>  4472
<211>  186
<212>  DNA
<213>  homo sapiens

<400>  4472
gataacaatt ctgggcacgg tgaagcccaa tgcaaacaga attgctttag atttccaaag       60

agggaatgat gttgccttcc actttaaccc acgcttcaat gagaacaaca ggagagtcat      120

tgtttgcaat acaaagctgg ataataactg gggaagggaa gaaagacagt cggttttccc      180

atttga                                                                 186


<210>  4473
<211>  590
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (398)..(398)
<223>  n is a, c, g, or t

<400>  4473
aaactggaca agtacgactc ggtggaggcc atcaaggcat ttaacaaaaa caacttgatc       60

ctagaggaaa gaaacaaata cttcaaccca catctcactg ggaagaccta ttctaatgcc      120

tactttacag atctcaataa ttatgatgag tactaacagc tttcatgttt ttggcttctt      180

gtaaatcccc agttcctcaa ggcctgtgcc ccatgactgc ccatgtttct gaggcttcag      240

agtcgaagtt tggatacatt tcaagtgcat ttcaagccac cagagtgtcc cattgctgcc      300

aaaaatacac gtctttaaaa gcaacaaaaa ttgaaataag acatcgtgaa aatcttgacc      360

attgttgaat gagccagggt ggtgaagttt ttaattgntg ttcatcctat ttttctgaca      420

agtccattgg tttgtttttt gagcattatt ttataaatgt gccacccaca ttggaaggag      480

tctttcttta gaactttgga gtgtaaatct tcatgatgtt gtaaattcaa gaaaataggc      540

actttctctg aaagacctgc tccttccaca agaagtgcat aggtccataa                 590


<210>  4474
<211>  316
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (126)..(126)
<223>  n is a, c, g, or t

<400>  4474
aatatcctgt acttgtcact catgtaaaac taatgtatca aaattagcat atatggaaga       60

aaaatcacta ttcaaaaata gtttcaattg ggcaaatgtg tgtctacaac tttgttgaaa      120

tggcanagtc tgtgttgatc ctcatataca ataatgttgt tgtaacacaa gtgttattag      180

accatagcca caaaatattt aatgtgttgt gccttcatga tgtaacagaa cattctccag      240

gtagggtagt tgggggaaat aaagggataa atctctaatt attgctgttt aactgtttgt      300

tatcatagtt ggtcaa                                                      316


<210>  4475
<211>  315
<212>  DNA
<213>  homo sapiens

<400>  4475
caatgccatc ttgcgctaca tcgctcgcaa gcacaacatg tgtggtgaga ctgaagaaga       60

aaagattcga gtggacatca tagagaacca agtaatggat ttccgcacac aactgataag      120

gctctgttac agctctgacc acgaaaaact gaagcctcag tacttggaag agctacctgg      180

acaactgaaa caattctcca tgtttctggg gaaattctca tggtttgccg gggaaaagct      240

cacctttgtg gattttctca cctatgatat cttggatcag aaccgtatat ttgaccccaa      300

gtgcctggat gagtt                                                       315


<210>  4476
<211>  249
<212>  DNA
<213>  homo sapiens

<400>  4476
caaaggcatg attattagaa actatttaag cttttttctt tgaaaaacaa gctcctttta       60

cagaatataa acaacagtag tgcctgtggt ttagcccacc aatcttgatg actaaaagta      120

gctgatgcat tgtgcatatg atgcttgaga tggtttttgc aaaagcagaa atcgctgcaa      180

ggtaatcaca atagataaaa gtggtatttt aaacctttga aataaatgga tgtaactgta      240

ccttggtac                                                              249


<210>  4477
<211>  386
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (178)..(178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (182)..(182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (191)..(191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (217)..(217)
<223>  n is a, c, g, or t

<400>  4477
aataatgggg cctatgactt gaatgaatag aaatgaataa gctggtgttt gttttttcaa       60

aatggaagta atttagattt gttctcctca tacataaaat gattttagtt cagttttaac      120

cagtgaaaac tttgttttta tgaaaaaaaa aaggaaaatg gtttcccatt tggttttnat      180

antgtgttaa nataaaaatg tgtaaagtaa cccaccnaaa tgttattaga atttttcttc      240

tagcatttat aattttttca actcctattg tgtttctttg tgtgtgatat tttaatcaaa      300

agtggttgag ttgttaacag tgttctttga aagaatctct aaaaggctta taaatgtttg      360

aaatatcaca caaaggctga tttcta                                           386


<210>  4478
<211>  403
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (67)..(67)
<223>  n is a, c, g, or t

<400>  4478
ctgtatctat tcttctgacc atctagtgac tcaggatatt aggcccagtt gaagtggagt       60

tataggnatt ttccacacat tcacgcatac ttggatatca accctctcta caggtccgtt      120

tccttacaca ttttatcccc ctcagaacac gataaaccat ggccaattca gtttcacttt      180

ggggcccaat tacttgaagt atcccacaga aaatgtaaac tgctcgcctt attcccccaa      240

actttttgtt catgtggcag ggagcagtac acaactatgg aatagattat taaaactgaa      300

cttgaagcta acgttagaat agtggttaac agagctaaga aataaggcta accatcgaaa      360

agaacatggg ccgcgggtaa actagctttg ctctttagat gca                        403


<210>  4479
<211>  358
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (112)..(112)
<223>  n is a, c, g, or t

<400>  4479
aaatttacta ttcctaaccc gaatgaaatt agcctttgcc ttattctgtg catgggtaag       60

taacttattt ctgcactgtt ttgttgaact ttgtggaaac attctttcga gntttgtttt      120

tgtcattttc gtaacagtcg tcgaactagg cctcaaaaac atacgtaacg aaaaggccta      180

gcgaggcaaa ttctgattga tttgaatcta tatttttctt taaaaagtca agggttctat      240

attgtgagta aattaaattt acatttgagt tgtttgttgc taagaggtag taaatgtaag      300

agagtactgg ttccttcagt agtgagtatt tctcatagtg cagctttatt tatctcca        358


<210>  4480
<211>  549
<212>  DNA
<213>  homo sapiens

<400>  4480
acgccgactt taccaaccaa gatattgtat gtgtgtgaca ttcagctaac attgatctag       60

gcacttagtt tgctaccaca ttgttccctt cattgattga aactgtaaat aacataacac      120

tttaaggcag ctaagcaaat attttaataa gccatgaaag gcaagatgcc agagaaaatc      180

tgtatattca gctatttgga gaactcgtgt tttccacaaa ttaaactgga gatgtcattt      240

gaaattttct tcccttaaac atgctgtcac aacatggatt ccttctcatg gatgtctttc      300

taggcttata aatatatggt gtgattgcta taattttgtg aaattttatt cagcaattaa      360

tagtgatttc agcaatatgt actaagattc caaggcagaa ataaatgtat aaaggatttg      420

agcctgtatg tgtaagaaga aactctctct tcagtcatat ttcctaaatt cagtgtaagt      480

acctcgctga tttagcactg gagttattcc ttgaatgtgt aaataatgat gttctattct      540

gacctaatg                                                              549


<210>  4481
<211>  434
<212>  DNA
<213>  homo sapiens

<400>  4481
gaggatctgc accatagtga ccggcctggg ttgtggcctc ctcctcctgg tggcgctcac       60

tgccctcatg ggttgctgtg tttccgacct catctccagg acagtgggaa gagtggctgg      120

aggaattcag tttcttgggg gcttgttgat tggtgctggc tgtgccctct accccttggg      180

ctgggacagt gaggaagtcc ggcagacttg tggctacact tctggccagt ttgacctggg      240

gaagtgtgaa atcggctggg cctactactg cacgggagca ggtgccactg ccgccatgct      300

gctgtgcacg tggctggctt gcttttcggg caagaaacag aagcactacc catactgaga      360

tggagctacc aagagcagac agaggagaag atgggccaaa ggggcttgga gaggtcaaaa      420

catccaccta cctt                                                        434


<210>  4482
<211>  525
<212>  DNA
<213>  homo sapiens

<400>  4482
aaactctaca ctctggatgg aaaacaggta acttgtctcc atgatttctt tggtgatgat       60

gatgtgttta ttgcctgtgg tcctgaaaaa tttcgctatg ctcaggatga tttttctctg      120

gatgaaaatg aatgccgagt catgaaggga aacccatcag ccacagctgg cccaaaggca      180

tccccaacac ctcagaagac ttcagccaag agccctggtc ctatgcgccg aagcaagtct      240

ccagctgact caggtaacga ccaagacgca aacggaacct ccagcagcca gctctctacc      300

cccaagtcta agcagtctcc catctctacg cccaccagtc ctggcagcct ccggaagcac      360

aaggtagacc tgtacctgcc tctgtccttg gatgactcgg actcgcttgg tgattccatg      420

taaaggaggg gagagtgctc agagtccaga gtacaaatcc aagcctatca ttgtagtagg      480

gtacttctgc tcaagtgtcc aacagggcta ttggtgcttt caagt                      525


<210>  4483
<211>  203
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (49)..(49)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (139)..(139)
<223>  n is a, c, g, or t

<400>  4483
gccagacatc aaattaagct caaattaagc tctcgtttaa atgtttaanc acctaattta       60

tattctaatt gatcccagcc actgatgcat gtactttagc tacttctgct aaataagcat      120

attaattttc cacatcagnc catcagatct tgagaaccaa cagttatcta gaattccgtg      180

tctactaatg tttcacctgc atg                                              203


<210>  4484
<211>  477
<212>  DNA
<213>  homo sapiens

<400>  4484
tcttctttat ttcttgggtc tcactctcat cacccaggct agagtgcagt ggcacaaaaa       60

tctcggctca ctgcagcctt gacttcccag gctcaggctc aggtgatcct cacaccttag      120

cctcccaagt acctgggact acaggcacgc accaccatgc ctagctattc ttttgtattt      180

ttggtagaga cagggttttg ctgtgttgct caggctggtc tggaacccct aggctcaaat      240

gatgtgccca actcggcctc ccaaagtgct gggattacag gcatgaaccg ccatgcctgg      300

cccttgattt tttcttttta agaaaaaaat atctaggagt ttcttagacc ctatgtagat      360

tattaatgaa caaaagatta aactccaaaa tattaaatag taagcctgaa ggaatctgaa      420

acacttgtac ttccaatttt ctttaaataa tcccaaatag accagaattg gcccata         477


<210>  4485
<211>  569
<212>  DNA
<213>  homo sapiens

<400>  4485
agcctgcggc ccgtttacgc ggacgccgcg ggcactgctc tgcccgccgc gcgcccggag       60

gacggccgac cgcggctggt ggtgacgccg gccagcagcg gcggcgacgc ggcgggcgtg      120

agcttccaga agacggtgct ggtgggggcg cgccagcagg gccgcctgct ggtccgccac      180

gcctacagct tccaccagag cagcgaggag gccggcgact tcctggcgca cgccgacctg      240

cagcggcgca actccgagta cctggttgag aacgccctgc acctgcacct catcgtcaag      300

cccgtatacc acacccttat ccggaccccc aagtagcctc ggggtctggg aataaaggcc      360

tggcctaggt ggtccctgtg ggtctgggaa gggcaaggcg agcctggagg tggcaacaag      420

cctggtcccc tggatggcca ggcgccggcc accctagggc tggggtggag tccaggtgag      480

gcgtggtaga caagatgcct ggtttcaaga gctgatttca cagctgactt gaaggaacgt      540

tcttggtcct gaataaaccg atgctcaga                                        569


<210>  4486
<211>  457
<212>  DNA
<213>  homo sapiens

<400>  4486
acttcatcaa tgagggactc cgcgctgctg acaacgaccc cacggcaccc ccctatgact       60

ccctgctggt cttcgactac gaggggagcg gctccaccgc aggctccgtc agctccctga      120

actcatccag ttccggggac caagactacg attacctcaa cgactggggg cccagattca      180

agaagctggc ggacatgtat ggaggtggtg aagaggattg actgacctcg catcttcgga      240

ccgaagtgag agccgtgctc ggacgccgga ggagcaggac tgagcagagg cggccggtct      300

tcccgactcc ctgcggctgt gtccttagtg ctgttaggag gccccccaat ccccacgttg      360

agctgtctag catgagcacc cacccccaca gcgccctgca cccggccgct gcccagcacc      420

gcgctggctg gcactgaagg acagcaagag gcactct                               457


<210>  4487
<211>  549
<212>  DNA
<213>  homo sapiens

<400>  4487
ggtttaggtc tcagtcaagc agcagcaaca ggggctttgg ctgcagcagc tgccagtgcc       60

aacccagcag cagcagcagc caatttattg gccacctatg ccagtgaagc ctcagccagt      120

ggcagcacag ctggtggtac ggcggggaca tttgcattag gtagcctggc tgctgctact      180

gctgcaacca atggatattt tggagctgct tctcccctag ctgccagtgc cattctagga      240

acagaaaagt ccacagatgg atccaaggat gtagttgaaa tagcagtgcc agaaaactta      300

gttggtgcaa tacttggcaa aggagggaaa acattagtgg aataccagga gttgactggt      360

gcaaggatac agatctccaa aaaaggagaa ttcgtacctg gcacaaggaa tcggaaggta      420

accattactg gaacaccagc tgcaacacag gctgctcaat atttaattac acaaaggatc      480

acatatgagc aaggagttcg ggctgccaat cctcagaaag tgggttgagt gccccagtta      540

cacatcaga                                                              549


<210>  4488
<211>  514
<212>  DNA
<213>  homo sapiens

<400>  4488
aatacatcat ccgaactctg agccgagtgg aattcctggg aatgattggt ctctttggag       60

catttttcag tggaattcaa ttagctataa tggagcataa ggaactgttg aaggtgccct      120

gggactggca aataggactg ctctacgttg gctttagtgc ctgcatgttt ggtctctaca      180

gctttatgcc agtcgtcata aagaaaacca gtgccacttc agtcaacctc tccttgctca      240

cagcagactt gtacagcctg ttctgtggat tgtttctctt ccactacaag ttttcaggac      300

tttatctcct gtctttcttc accatcctca ttgggctggt gctctactcc tccacctcca      360

cctacatagc ccaggacccc cgagtgtata agcagttccg caatccttca ggacctgttg      420

tggacttacc gaccacagct caggtggaac cctcagtcac ctacaccagc ctgggccagg      480

agaccgaaga ggagcctcat gttcgtgtgg ccta                                  514


<210>  4489
<211>  356
<212>  DNA
<213>  homo sapiens

<400>  4489
aggcttccaa gctgcccatg tccatcatca tcgtgggcgt gggcaatgcg gacttcgctg       60

ccatggagtt cctggatggg gacagccgca tgctgcgctc ccacacgggg gaggaggcag      120

cccgcgatat tgtgcagttc gttccctttc gagagttccg caacgcagca aaagagacct      180

tggccaaagc tgtgctggcg gagctgcccc aacaagttgt gcagtatttc aagcataaaa      240

acctgccccc caccaactcg gagcccgcct gagctccagt gcccagcagc agcatgtcag      300

ctgagcctcc tgccctcccc caggaacatg cacgctcact ctgcttcctt gtgggt          356


<210>  4490
<211>  413
<212>  DNA
<213>  homo sapiens

<400>  4490
tgcagcccat ctggcggagc ggcggcggcg gcggcggcgg cggcaggaga atggcatcag       60

aactggcaat gagcaactcc gacctgccca ccagtcccct ggccatggaa tatgttaatg      120

acttcgatct gatgaagttt gaagtgaaaa aggaaccggt ggagaccgac cgcatcatca      180

gccagtgcgg ccgtctcatc gccgggggct cgctgtcctc cacccccatg agcacgccgt      240

gcagctcggt gcccccttcc cccagcttct cggcgcccag cccgggctcg ggcagcgagc      300

agaaggcgca cctggaagac tactactgga tgaccggcta cccgcagcag ctgaaccccg      360

aggcgctggg cttcagcccc gaggacgcgg tcgaggcgct catcagcaac agc             413


<210>  4491
<211>  104
<212>  DNA
<213>  homo sapiens

<400>  4491
gaaagttctg tctcctttag cccggtttgt ttctccctgc tcaggtctag aatcccaagc       60

agtgttcttt tctggtgaac actgtgagcc gcagatgtga cttt                       104


<210>  4492
<211>  328
<212>  DNA
<213>  homo sapiens

<400>  4492
gagtcattca cctaaccaag ctaagaaacc tttccagctt ggacctacgt catatcactg       60

aactggataa tgaaaccgtg atggaaattg tcaagaggtg caaaaatctt agctctctca      120

atctctgtct gaactggatc ataaatgaca ggtgtgtgga ggtcattgca aaggaaggac      180

aaaacctgaa agagctatat ttggtgtcct gtaaaatcac agattatgca ctgatagcca      240

ttgggcgata cagcatgaca atagagactg tggatgtcgg atggtgtaaa gaaatcacag      300

accaaggagc caccctgatt gcacagag                                         328


<210>  4493
<211>  303
<212>  DNA
<213>  homo sapiens

<400>  4493
ttcatcctag gagggcccag cttgggagtc tgcctccccc tgatcccagg accacccaca       60

ggagaggggc agtgtccatc tttctgaagg gaccctttgg agatctcgtc ctaagtgtgg      120

agaggactga cgtggccctg tcatctcaac acatcccagg gtcaggcagg cctcagctga      180

aacaatgtca gggtcctcaa gggtcccatt tagacagacc cacggcttgt aacagtgcgc      240

tcctcaggag gcagcactag cgcataccca ctccccacgg acactgagtt cctggtgaca      300

gct                                                                    303


<210>  4494
<211>  135
<212>  DNA
<213>  homo sapiens

<400>  4494
gctttttctt gccagcttgg gccattcttg cttagacagt cagcatttgt ctcctccttt       60

aactgagtca tcatcttagt ccaactaatg cagtcgatac aatgcgtaga tagaagaagc      120

cccacgggag ccagg                                                       135


<210>  4495
<211>  330
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (103)..(103)
<223>  n is a, c, g, or t

<400>  4495
gagatgctaa gagaatgcct gcaaaagaag tcaccattaa tgtaacagat agcatccaac       60

agatggacag aagtcgaaga atcacaaaga actgtgtcaa ctnagcagag agtccaagca      120

gaagggcaga tggacttctt cagtgtcctt cacggcactg gatcccatca aagaaccttg      180

aagaagtggc tgccccttgc tggacctgaa ttctactgag tccctggcaa gactgtctta      240

cctggcagca aactgctgcc tgatttgttg ggaccttctg agccttctac ttatcatgta      300

aatgtattgg cacagtgctt acatatgtta                                       330


<210>  4496
<211>  493
<212>  DNA
<213>  homo sapiens

<400>  4496
gaaaagcaac tcgacctgtt cagagtctcg cacttagttg atttagcttc tcaaaaaaat       60

gaatgttcat taaaatctga ggcaccacga gcagctccct tgaagtgatc atcctgtgga      120

ttccggagac ctgattttct tctcccatgg agcccgagag aatcttggag gcttcctggt      180

gcagagttat atttatggcg gtgactccgt ctgaactctg ccgaggcaag cccagccaag      240

gacgtgccag cggccgaggc acccggctgt ggttgtcctg atagcattat tcatctggtc      300

ttggccatgg agacagtcat ccaggatatt gattttgctt ttgtctgtag tccaagattg      360

tcaagcaaac attttgaccc ttctggaaac aaaaggtacc tttgttccag catagaaaga      420

ttctgtggca tctcataagc catcagcacc ccttttcctc ctcttccttc tcacgatctt      480

actgctgtct gaa                                                         493


<210>  4497
<211>  533
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (63)..(63)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (103)..(106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (342)..(342)
<223>  n is a, c, g, or t

<400>  4497
gaccttaagg gttgccatca catctttctc acactctcct cttgataata ataataataa       60

aangtttgct aaggattaaa gaaatgggaa aaataaaaaa aannnncttc aaatttacag      120

gaatgaatca ttgttcttag ctttgttgca tacacaaact tcttggattt tgttgtgcag      180

tattgacgtg agataaagct caacattgaa taatctttca gtggtacttt tcaaagtctt      240

cccctcctct gcctcataat taagggaaaa gacaaaattg aaagacacac tgtctttatc      300

tatcctggtg tatgttggca ccttagctac tttttttttt tncctttttg cacaaggtgc      360

tttcctgata tgttcaacat gccatctttg ggtgataatg tatatgccgt gatggggctc      420

aggcccctta ggggagtgtc tataagaact gcctatttat gctcatttac ctcaagactg      480

tcctctctac cctaatctag ttgtcatcac tccatctttt gtactgctgt tga             533


<210>  4498
<211>  310
<212>  DNA
<213>  homo sapiens

<400>  4498
agtgatctct ggaagcgcta aagctaaaat ttctgttctt gaaacacttc agctttgcaa       60

ctaaaatatt acagattaat aataaattaa accaaccaat gataaacact actcagtcca      120

ccaacaacaa acgtgtttga attcacctta ccaatattaa tcccagcgtg tgtaaaacag      180

aacagtaact ctatgtgacc ccagataaca ttttgtaaca ttgtgcttcc ttgtagtttg      240

taatgtgagt tcaatcagta tttatgttga aatttctaac attaaatcta gtctctatcc      300

tgttaattta                                                             310


<210>  4499
<211>  244
<212>  DNA
<213>  homo sapiens

<400>  4499
taaaaacagt ttggatctct tagtattgcc tttgaaactg caacataagc aactcaacaa       60

tattagttgc attcctttat agacatacca tgtcaaagac gtttttctat caagttgtat      120

tctttcctgt tctataacct ttgtcatctg ttagactctg tatgtgtgat ttgtaaaaag      180

caggctgaaa ctatggacat gatttctgaa gagcacatct ccactgactt tcataaagca      240

aatg                                                                   244


<210>  4500
<211>  205
<212>  DNA
<213>  homo sapiens

<400>  4500
cctgagccac ggctggagag accgagaccc ggcgcaagag agcgcagcct tagtaggaga       60

ggaacgcgag acgcggcaga gcgcgttcag cactgacttt tgctgctgct tctgcttttt      120

ttttttctta gaaacaagaa ggcgccagcg gcagcctcac acgcgagcgc cacgcgaggc      180

tcccgaagcc aacccgcgaa gggag                                            205


<210>  4501
<211>  476
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (255)..(255)
<223>  n is a, c, g, or t

<400>  4501
aattttgcat tgtgtgagct tctacagatt ttagacaagg accgttttta ctaagtaaaa       60

gggtggagag gttcctgggg tggattccta agcagtgctt gtaaaccatc gcgtgcaatg      120

agccagatgg agtaccatga gggttgctat ttgttgtttt taacaactaa tcaagagtga      180

gtgaacaact atttataaac tagatctcct atttttcaga atgctcttct acgtataaat      240

atgaaatgat aaagntgtca aatatctcag aggctatagc tgggaacccg actgtgaaag      300

tatgtgatat ctgaacacat actagaaagc tctgcatgtg tgttgtcctt cagcataatt      360

cggaagggaa aacagtcgat caagggatgt attggaacat gtcggagtag aaattgttcc      420

tgatgtgcca gaacttcgac cctttctctg agagagatga tcgtgcctat aaatag          476


<210>  4502
<211>  537
<212>  DNA
<213>  homo sapiens

<400>  4502
ccccgaagaa tgatgatacc ccaaataggc agtactggga tgaagatctg ttaatgaaag       60

tgctggaata cctcaaccaa gaaaaggcag aaaagggaag ggagcatatt gctaagagag      120

caatggaaaa tatgtaagct gctttcatta attaccctac tttcattcct cccaccccaa      180

gcaaatccca acatttctct tcagtgtgtt gacttctatc ctgttaacac tgtaatatct      240

ttaaatgatg tacaggcaga tgaaaccagg tcactgggga gtctgcttca tttcctctga      300

gctgttatct tgtgtatgga tatgtgtaaa tgttatgact ccttgataaa aaatttatta      360

tgtccattat tcaagaaaga tatctatgac tgtgtttaat agtatatcta atggctgtgg      420

cattgttgat gctcacatat gataaaaaag tgtcctataa ttctattgaa agtttttaat      480

atttattgaa ttattttgtt actgtctgta gctgttttgt ggagtactgg accaaaa         537


<210>  4503
<211>  250
<212>  DNA
<213>  homo sapiens

<400>  4503
gatatgtcca atttcctggc tcatttcatt gtgctctatg ggtacgtata aaaagcaaga       60

attctgtttc ctaggcaaac attgcaactc agggctaaag tcatccagtg aaacttttag      120

agccagaagt aactttgtcc cagtcctaca atgtgaaaag agtgaatagt tgcctctttt      180

tagccatttt catggctggt acatattcgt acgcattact tttcagaatc aatacgcact      240

ttcagatatt                                                             250


<210>  4504
<211>  466
<212>  DNA
<213>  homo sapiens

<400>  4504
gttatacatg tgacttactt ttgactcagc ctgagaggag gaaatgtaaa gagataagag       60

atttggccca aagcagcaag agactagtaa ccttgagcca ggacgaagcc aagacaacgt      120

gactcccaag tagcaggagc agaggtcggt cacctgtggc attctgtttc attccctttt      180

aaaattatga gactttatag gcagtgtaaa acatcagcag gcagcgatgt gataggatgt      240

gcgaaaaagc tggtctgata ccatggctat aattacagag ctttagttca attaggattt      300

tgtaaatgag caaatgacct ttttttccag tgccccttgt aatagttaat atgagtccat      360

gcaatcttgt gatgccattc tcctgaaggt gttgatttct ggtacccagc cagcttagct      420

ttggctgctg gaagcacagt aggtactgat gattacttcc tggaaa                     466


<210>  4505
<211>  137
<212>  DNA
<213>  homo sapiens

<400>  4505
caaaatgcag ctcctgggct gggttttggg ggaaaaaaaa aaaatgtgtt ctgtcctggt       60

ctggagtccg ttgctgcagt ctccttggtt agttaagaca aagccctcat taacgtttgc      120

tgcaggactt aaaattt                                                     137


<210>  4506
<211>  268
<212>  DNA
<213>  homo sapiens

<400>  4506
attgcactga cacttaagac ttgggaagcc tgacatttct atctggacag tgtgactatc       60

ttatgtcagg accttcatgt gccaaacgtc agtggtgttt tcatatggta acttctcact      120

agtcaggcta gtggagagat gaccaggtgt acagttctga ccatcctgtg ttgtaagtac      180

ccgtggaatg gatttgtaag gtaatcttta tagataaacc tcaagcaacg attcatgttg      240

taaccgcttc atatggttta gttttcaa                                         268


<210>  4507
<211>  387
<212>  DNA
<213>  homo sapiens

<400>  4507
aggtcaattg tatttcctct tggaaagcag tttaacatgt aagcgttcaa agatgtgatt       60

cagataaaaa tacccaggtc catagtgaaa gatgtttttc agtatgttac ttatggttta      120

gctactagcc agggaggtgg tagcccagag aaggcaaacc acatacagat cacctggagt      180

tgattatatg agtctatgct tttgagctct ttaggcaaca cattctcatt cctgtcatta      240

tcagttgaac ctccatgcca cacatttcta agaattaaat gcctagatgg attaaatgta      300

gtatgtgaat gttctatgta aaagccaata gagtatacaa gtgacttgaa tgatttttcc      360

taacttgttt gcaactgata gctcata                                          387


<210>  4508
<211>  273
<212>  DNA
<213>  homo sapiens

<400>  4508
tttctctgtc aagcttgaac taatgtaaat aattgaaata atgtaaagtt atattttcat       60

gtttttatag atacaacatg acaagaatac ataatgtaag agtatttcaa ctatggataa      120

tgttgattgg ataatgcaca tctcagttac aagcagtact catagtttaa tatccatgta      180

acggtgcatc aatatattgc tatataaata tgtctgtgtg catataagtg aaaagtggtc      240

aaacaagagt gatgacagct gtctaaaggt ttt                                   273


<210>  4509
<211>  527
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (376)..(376)
<223>  n is a, c, g, or t

<400>  4509
gatatcacaa tcacttttct tactttctgt ccatagtact ttttcatgaa agaaatttgc       60

taaataagac atgaaaacaa gactgggtag ttgtagattt ctgcttttta aattacattt      120

gctaatttta gattatttca caattttaag gagcaaaata ggttcacgat tcatatccaa      180

attatgcttt gcaattggaa aagggtttaa aattttattt atatttctgg tagtacctgt      240

actaactgaa ttgaaggtag tgcttatgtt atttttgttc tttttttctg acttcggttt      300

atgttttcat ttctttggag taatgctgct ctagattgtt ctaaatagaa tgtgggcttc      360

ataatttttt tttccnacaa aaacagagta gtcaacttat atagtcaatt acatcaggac      420

attttgtgtt tcttacagaa gcaaaccata ggctcctctt ttccttaaaa ctacttagat      480

aaactgtatt cgtgaactgc atgctggaaa atgctactat tatgcta                    527


<210>  4510
<211>  539
<212>  DNA
<213>  homo sapiens

<400>  4510
atcaggtgtc ctacgattac agcgcgggct acagccgcac cgcctattcc agcctttgga       60

gatccgacgg ggtttgggaa ggggcgccgg gggaggaggg ggcgcaccgg gactgacttc      120

gaggcacgct tcccttcatt agagacggct gtggagagcg ccgcgcctcc gtgggtttct      180

cctaaatctg aagaacgatg ggaaaatgca cgtggagatg aaaccagatt tttaaaaatt      240

caattaataa aagcaacttc agaaaaaaga gatgaagacg agttggggat tgtttaatca      300

caacctcaag tgttaaaaca aaaacaaaca aacacgtttg taggttctta ctggaccaga      360

ggagtcaaga aaccaagatg gtttggggta tggggtgggg acggcaaaag gggtaagagc      420

tggcttctgt agccacctgt cccttctatt tttcagcgaa ggtcagtgta tttagtgtaa      480

ttaccccttc taaacagtgt cctagtccct cccttccctc tccttgagtg cattttgaa       539


<210>  4511
<211>  199
<212>  DNA
<213>  homo sapiens

<400>  4511
ggtacttgtt ttcaccattg ggctaacttt gctgctagga gttcaagcca tgcctgcaaa       60

tcgcctctct tgctacagaa agatactaaa agatcacaac tgtcacaacc ttccggaagg      120

agtagctgac ctgacacaga ttgatgtcaa tgtccaggat catttctggg atgggaaggg      180

atgtgagatg atctgttac                                                   199


<210>  4512
<211>  366
<212>  DNA
<213>  homo sapiens

<400>  4512
tgaatctgct gttctaccca tgtgtctcac attcatttgt attatttcaa gaaatgtact       60

aatttccagt tcactcaggc cttactaatc cataccaaat tagcctaaag acaaggcatt      120

ttatattcat ttctattttc agcatgtttc taccaaagct attagaacca acacgtacct      180

ctgaatgccc gattataaga agacatgaga agactttaaa agttttggaa atttacagag      240

ccatgatttt tgaacctaat tgaaagaaaa ccatctgaat tgttgcaggt ccacattttt      300

gccaaagata cactctatag atgcttagta gtggcctgat ttttttccat gtattgccac      360

gacaaa                                                                 366


<210>  4513
<211>  115
<212>  DNA
<213>  homo sapiens

<400>  4513
gtgcccatgg aacactgcat aacccgtttc tttgaggagt gtgaccccaa caaggataag       60

cacatcaccc tgaaggagtg gggccactgc tttggaatta aagaagagga catag           115


<210>  4514
<211>  446
<212>  DNA
<213>  homo sapiens

<400>  4514
atacacatgc tataagttcg ccttaagatt tcaattcttg gataatcagg ctctgtttgc       60

actttatatt ttagcagata cagtctctta gtcactaggc tttgcatttg tatgtagctg      120

tatgtttccg tccattttct taatcctgaa cctgtatgtt aaatgaagat ggcaattttt      180

ttcttgtata gtacttgtat tttctttcgc tgatgcagct ctgtctcaat ttttaaacct      240

ttgctgttaa atgcaatact ttataaagaa tgaacaaaat tactggaagc agtattgtaa      300

gtaatgaggt agtattaatc agttttatct tttgaaaggc acagtctaaa tcgaaaccct      360

aaactcaatg ctgcaagtat gaatttaatt catatataag atctatttaa atataagagt      420

agcaatactg cacctggtga tcacaa                                           446


<210>  4515
<211>  489
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (164)..(164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (180)..(180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (206)..(206)
<223>  n is a, c, g, or t

<400>  4515
catttaatgg atgcaactca gtttatttaa ccattcccat gttgttaact atttaggttg       60

tttctaattt tcattattat aaagttgcag aaatttggtg tacataaaac tgtctccata      120

taattgatta ttaggatata ttcccatgaa ggattctttt tttnaaaaaa atgtgaaatn      180

tcatcttgta cttacacctt tcatgnaaag ggatttcctg cttttgtact gcatgggtgg      240

cagttgtgag gaaaagccag tcaaatgacc tttttacaaa agaaatgcag tggtcacttc      300

agttgagagt gactttttaa tacaacaaga tcaactagaa gaattcaact gtctcaagaa      360

tcaaggtacc ccaatatatc tcgcaattcc aaactttgtt tgagggactc gttatccagc      420

tcttggtagc cacacctgca atgtaaaatg gaagaaaatg caaagaaacc aaatgtgccg      480

agtgaataa                                                              489


<210>  4516
<211>  480
<212>  DNA
<213>  homo sapiens

<400>  4516
ctagactagg agctttatca ggttctagga ggtcctttag gaagactctc aaaggcaaat       60

ccctgatccc ccgccccacc cttagccctg ccctctcacc agagcaaaat tcactgggga      120

cttttcccac cacacatgga aatctgtcca ctcggaatac ctctgttttc catttcaaat      180

tgtaggggga ggggatggaa cacttccagt gatggtaaga gatctgttat gaaacgaaac      240

accccccgtg ttaataactt ggtctgaaat ctgtttttat gagccgggcc ccctgtgcct      300

ctagtatact tgtattgact ctcatagtta cccttttagt tttactgtgt tctgtgaaaa      360

tttgtaattg gttgagaatc actgtgggcg tccattctta ttcaactaaa tctccacagg      420

ttttttgagc tggtgtggat tagtttaact cttgtattca accattagtg ctaccacctt      480


<210>  4517
<211>  491
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (179)..(179)
<223>  n is a, c, g, or t

<400>  4517
aaagcaccac tacaatgtcc attttaatgg cctggaatgc aaaacgcctg aagaatacaa       60

aggatggtct gtgggaaaat atattagaag ttactatgaa gaatgcccca aagacaagtt      120

accagcatat cctgagtcat ttgaccaaga cacagaagat gatgaatggg aaaaaaaanc      180

atagagatca caccgcaaag aagcaaagcg taataattac tatagtagga taaggtagaa      240

attgttctga ttgtaattag ttttgtattt tctatactgg tgttagaaaa catatgttta      300

catttgatta actgtgttgc ctatttatgc agggtaatcc agctaaagga agctttcttt      360

aattataagt attattgtga ctattatagt aatcaagaga atgctatcat cctgcttgcc      420

tgtccatttg tggaacagca tctggtgata tgcaattcca cactggtaac ctgcagcagt      480

tgggtcctaa t                                                           491


<210>  4518
<211>  230
<212>  DNA
<213>  homo sapiens

<400>  4518
tgtcagtatc atgttctcta attatcttgc caaattttga aactacacac aaaaagcata       60

cttgcattat ttataataaa attgcattca gtggcttttt aaaaaaatgt ttgattcaaa      120

actttaacat actgataagt aagaaacaat tataatttct ttacatactc aaaaccaaga      180

tagaaaaagg tgctatcgtt caacttcaaa acatgtttcc tagtattaag                 230


<210>  4519
<211>  574
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (396)..(396)
<223>  n is a, c, g, or t

<400>  4519
gggttgctgc aagcactcat caccgctctg gggacctctt caagttctgc caccctaccc       60

atcaccttca agtgcctgga agagaacaat ggcgtggaca agcgcgtcac cagattcgtg      120

ctccccgtag gagccaccat taacatggat gggactgccc tctatgaggc tttggctgcc      180

attttcattg ctcaagttaa caactttgaa ctgaacttcg gacaaattat tacaatcagc      240

atcacagcca cagctgccag tattggggca gctggaattc ctcaggcggg cctggtcact      300

atggtcattg tgctgacatc tgtcggcctg cccactgacg acatcacgct catcatcgcg      360

gtggactggt tcctggatcg cctccggacc accacncaac gtactgggag actccctggg      420

agctgggatt gtggagcact tgtcacgaca tgaactgaag aacagagatg ttgaaatggg      480

taactcagtg attgaagaga atgaaatgaa gaaaccatat caactgattg cacaggacaa      540

tgaaactgag aaacccatcg acagtgaaac caag                                  574


<210>  4520
<211>  129
<212>  DNA
<213>  homo sapiens

<400>  4520
aaccatcggt ccacacctgg gcatttggtg agagtcaaag ctgaccatgg atccctgggg       60

ccaacggcaa cagcatgggc ctcacctcct ctgtgatttc tttctttgca ccaaagacat      120

cagtctcca                                                              129


<210>  4521
<211>  262
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (112)..(112)
<223>  n is a, c, g, or t

<400>  4521
aacattatct cctcttgtac agagtctatt tcttgtaacc atttgttaaa ctcttttctt       60

tttctgatct catggcatgc ttttatgtat tttgtacagg aggcaaaaaa antacttaaa      120

ataagcaaag aaactgaaca gaattgcata cattgggttg ttttttctgt gctgtctgta      180

cattgcttct gctgctgtga tttctaaacc tgtgctgtta ttcaactgac ttttttttgt      240

actttgaccc acgttttttt ga                                               262


<210>  4522
<211>  369
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (246)..(246)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (321)..(321)
<223>  n is a, c, g, or t

<400>  4522
gttaaacaag ggtaccacaa tatcatttat aattgatgtc aatattagta gtccacttta       60

tgcttaaaat aaaatcataa aaaatcaagt tttaaggtta tattttttaa aataatgaat      120

tttctatctc taggcaacat gtctttatta ttcaagctga atgtttaaga gagattttgg      180

tcttaaaggc ttcacatcat gaaagtgtac atgcatatgc aagtgtgaat tacgtggtat      240

ggatgnttgc ttgtttatta actaaagatg tacagcaaac tgcccgttta gagtcctgtt      300

aatattgatg tcctaacact nggtctgctt atgctagttc agtatttggt ctaggcttca      360

ttttgatat                                                              369


<210>  4523
<211>  522
<212>  DNA
<213>  homo sapiens

<400>  4523
attctatcgg tataaaggca tcgatatttt agatgcaccc gtgtttgtaa aaatgtagag       60

cacaatggaa ttatgctgga agtctcaaat aatatttttt tcctatttta tactcatgga      120

agagataagc taaagagggg acaataatga gaaatgttgg tgtgcttttc taagcattta      180

aaacataatt gccaattgaa accctaaata tgtttacata ccattaagat atgattcatg      240

taacaatgtt aaattaatta taatgggatt gggtttgtta tctgtggtag tatatatcct      300

agtgttccta tagtgaaata agtagggttc agccaaagct ttctttgttt tgtaccttaa      360

attgttcgat tacgtcatca aaagagatga aaggtatgta gaacaggttc acgtgattac      420

ctttttcttt tggcttggat taatattcat agtagaactt tataaaacgt gtttgtattg      480

taggtggtgt ttgtattatg cttatgacta tgtatggttt ga                         522


<210>  4524
<211>  450
<212>  DNA
<213>  homo sapiens

<400>  4524
attcagtttt ggtgtcctgg aaagcaagtt ctaaaattct caaatctagt gttaaatgga       60

cagcctttgt caagactgaa aattctcatg ctgcgcaaag tgctcgaata ccatctgatg      120

tcaaggtata taatcttact catctgaatc catcaactga gtataaaatt tgtattgata      180

ttcccaccat ctatcagaaa aacagaaaaa aatgtgtaaa tgtcaccacc aaaggtttgc      240

accctgatca aaaagagtat gaaaagaata ataccacaac acttatggcc tgtcttggag      300

gccttctggg gattattggt gtgatatgtc ttatcagctg cctctctcca gaaatgaact      360

gtgatggtgg acacagctat gtgaggaatt acttacagaa accaaccttt gcattaggtg      420

agctttatcc tcctctgata aatctctggg                                       450


<210>  4525
<211>  464
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (94)..(94)
<223>  n is a, c, g, or t

<400>  4525
tgcggatccc aaactgttcc ctttttcatt tcttgaaatg ttaccactac agacattttt       60

ttaaggtgaa taaacagttg tgatgtgctg tacntaaaat catgtttaat cgtataagga      120

aacatttcaa tacacttata caggaagaaa actatagatg aagtacatgt gtgtgattca      180

gtctgattca cagaattctg agagtaatat ggaataaaac aactccactt agatgataac      240

tgaagcattt cctgccttgt gaaaatttgg attttaaatt gctgttagaa tgggaaattt      300

ggacacttta tatcattgta taatttcaga atttagtttc tgtatctttt ggaaaacatg      360

attatagcaa aaacatagaa aataatctat tactaaaaca ccataaatgt aaaactagta      420

tgcttggctg ttaactctaa agatgttact tatgtctgtt ttta                       464


<210>  4526
<211>  504
<212>  DNA
<213>  homo sapiens

<400>  4526
gtgtaaactg aacccttatc cttgtcttca atcttcctcc ctgtagacat ctatcttatt       60

atggttatta ttcagaaaac ccagggatac aggtttgtct tcttactttg ataactcttc      120

ttagtttaaa ataataataa taacacatct ttggtcatct atgtcacaca aaaattttcc      180

tttgtttgcg gggggctggg gatgcagtgt tttttggggg gtcttggttt atgctccctg      240

cccttgagcc cctcagccgt ttgccctgcc cccacctcgg ctccatggtg ggagggggct      300

ctggtctttt ctaaagtggg cggtttgtct tttgatcttt cccttttgga tgtgcgtgtg      360

tgtctgcgtg tgccatgtgc gtggcacgca tatgagtgtg tgtgcgtgtg aacggctttg      420

ggtcctgctg gttttgctgt gagctgcagt gttctgtggg tctgtggtat ctgacactgt      480

ggacattaat gtacttcttg gaca                                             504


<210>  4527
<211>  450
<212>  DNA
<213>  homo sapiens

<400>  4527
ggatggctcc gcctgcactt ttgaaacccc ggtttccttc aacgtccaca ttccaggtga       60

ccacacgtgt ctcctcctcc tcatcttagc ttccaggttc accctaaccc tgtactaacc      120

tgcttggtgg acttggaaaa gacttggctc tgtcgggaaa ggagagacgg ggcctccatc      180

acgcctgtta ccagaggatc cccgagagcc acaccagctc tggacatcac cgcccctgga      240

actggggcca ccagccctgg gcacgagatt tgctctgact ttatttatat ggcatgaaat      300

ctctggttta ttttgggatt ttttgttgtt ggtgttgtca aagtttgttt tttctaaagt      360

tgtgtgatta tatatttgac attttacatt tcaaagaaag gtatgttgtc taacagggga      420

ccaacagaag gtagtattga caactgttcc                                       450


<210>  4528
<211>  467
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (398)..(398)
<223>  n is a, c, g, or t

<400>  4528
tgggaccacc atcagagcaa cggcctgcca cgacagtgcc aaaaagttgt gaggtcttcc       60

aggccaaggt ggatgggccc catgccaagg aatacaactt ttccctggaa accactaaag      120

taagttttgc ttttcctaaa gaaagtcttt taggacacca cccgtccccc gccctgctcc      180

agagcgtgga ccgaggaggt ctttgtgccc tgagcaggga ccggataaca ccagaaagag      240

ggatgctaca cgggggtttc tcctctcaag ataagtccct gagaattatt ttcaagcact      300

tttttctttt ttacctttaa gtttttcttc cttttgcttt aatatactga acacttggaa      360

gtcaccttta cttgcctttg cagaaaacag aacttagncc aaacctaagt aagagtcatg      420

cctggatatt gggataagcc agtgtctaga ggcctgaagg aaccgct                    467


<210>  4529
<211>  269
<212>  DNA
<213>  homo sapiens

<400>  4529
agccacaaca gtgactcggt ccacgtcccg ggcggtaaca gttgctgcaa gacctatgac       60

caccactgcc tttcccacca cgcagaggcc ctggaccccc tcaccctccc acaggccccc      120

tacaaccact gaggtgatca ctgccaggag accctcagtt tcagagaatc tttaccctcc      180

atcccggaag gatcagcaca gggagaggcc acagacaacc aggaggccca gcaaggccac      240

cagcttggag agcttcacaa atgcccctc                                        269


<210>  4530
<211>  370
<212>  DNA
<213>  homo sapiens

<400>  4530
tgcctgccac gagttctttg aacatgagtg agattagaaa gcagccaaac ctttcctgta       60

acagagacgg tcatgcaaga aagcagacag caagggcttg cagcctagta ggagctgagc      120

tttccagccg tgttgtagct aattaggaag cttgatttgc tttgtgattg aaaaattgaa      180

aacctctttc caaaggctgt tttaacggcc tgcatcattc tttctgctat attaggcctg      240

tgtgtaagct gactggcccc agggactctt gttaacagta acttaggagt caggtctcag      300

tgataaagcg tgcaccgtgc agcccgccat ggccgtgtag accctaaccc ggagggaacc      360

ctgactacag                                                             370


<210>  4531
<211>  490
<212>  DNA
<213>  homo sapiens

<400>  4531
gggactgtct gtcaaaagac tctgtatatc ttttgtggat gagttttgtg agagaacaga       60

gagaccattg tacctggcac aagggctcgt tcatgaaaag ggagacttac tgggaggtgc      120

aagacagtgg catttctcct ctcctcttgc tgctcagcac agccctggat tgcagccccg      180

aggctgagac cagacaaagc ccgggaggca gaaagatgct ccaagaacca acactatcaa      240

tgtctttgca aatcctcaca ggattcctgt gggtccagct ttggaactgg gaaacctttc      300

ttcggatccg cactcattcc actgatgcca gctgcccctg aaggatgcca gtactgtggt      360

gtgtgagtct cagcagccgc ccacacgctc ctaactctgc tgcatggcag atgcctaggt      420

ggaaatagca aaaacaaggc ccaggctggg gccagggcca gaggggaagg ccctggattc      480

tcactcatgt                                                             490


<210>  4532
<211>  343
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (46)..(46)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (126)..(126)
<223>  n is a, c, g, or t

<400>  4532
taacgtagag gcgatccgca gccggacaca ggaagcggga gctctnggtg tgtctgaccg       60

tggttcctgg agagacgcgg acagtaggaa tgaccaggca gttggtgtga gctttaaggc      120

ctctgntggg gaaggagacc aggcccacag agaacagggc aaggagcagg ccatgtttga      180

taagaaggtg cagctccaga gaatggtaga ccaaaggtcg gtgatttcag atgaaaagaa      240

agttgccctc ctctatctag acaatgagga ggaggagaat gatgggcatt ggttttaata      300

agcagaaaca ttttgtttta atggcagcct gttggcgacg tgc                        343


<210>  4533
<211>  127
<212>  DNA
<213>  homo sapiens

<400>  4533
tggagctggc catcccaaat tcaatcagtc catagagacg aacagaatga gaccttccgg       60

cccaagcgtg gcgctgcggg cactttggta gactgtgcca ccacggcgtg tgttgtgaaa      120

cgtgaaa                                                                127


<210>  4534
<211>  157
<212>  DNA
<213>  homo sapiens

<400>  4534
agcacttaca atcactaatt cccttaaggt tgaaactgta atgacataaa aagggtcgat       60

gatatttcac tgatggtaga tcgcagcccc tgcaacgtag cctttgttac atgaagtccg      120

ctgggaaata gatgttctgt ctctatgaca atatatt                               157


<210>  4535
<211>  574
<212>  DNA
<213>  homo sapiens

<400>  4535
atacacatat ccatctgcag accatggtcc ctaaacctgc agtttcttcc tgctggtgca       60

ggtacacaca cacacacaca cacacacaca cacacacaca cacactccat accatttcca      120

ttcaactcaa tctgcttagt tcgggtttga tccatttttc tcctctccat agttctacca      180

cccttcactg ctagtgtaca gctcacagca tctctcctac caccctggga aaagtcacat      240

tctaggctgg attctactga agtagaggcc tggtggttta acagccgaag acacacgcct      300

agggatgagc accctctttg tgacacttca tcctgatgcc aagatttttt ggagaacatc      360

tgcactttct tatatatata tataatatta aaaaaagcaa ctgggtatat atcactaaca      420

gctttgtagg aagcactttt aatgttttct ctctcacaca caaagattca aaagaaatgt      480

gcatatattt attctgtaat ttcagtgatt ataaattgta aaggtaatgt ttaatcattg      540

tatagtgatt atgcctctgg tatagctttc ctaa                                  574


<210>  4536
<211>  324
<212>  DNA
<213>  homo sapiens

<400>  4536
cactttacag actttgctgg agtttcaagc tgatgttaac atcgaggata atgaagggaa       60

cctgcccttg cacttggctg ccaaagaagg ccacctccgg gtggtggagt tcctggtgaa      120

gcacacggcc agcaatgtgg ggcatcggaa ccataagggg gacaccgcct gtgatttggc      180

caggctctat gggaggaatg aggttgttag cctgatgcag gcaaacgggg ctgggggagc      240

cacaaatctt caataaacgt ggggagggct cccccacgtt gcctctactt tatcaattaa      300

ctgagtagct ctcctgactt ttaa                                             324


<210>  4537
<211>  293
<212>  DNA
<213>  homo sapiens

<400>  4537
ggaaagcagg attccatcgc tggaacaatt acatgatgga ctggaaaaat caatttaacg       60

attacactag caagaaagaa agttgtgtgg gtctctaatt aatagattta ccctttatag      120

aacatatttt cctttagatc aaggcaaaaa tatcaggagc ttttttacac acctactaaa      180

aaagttatta tgtagctgaa acaaaaatgc cagaaggata atattgattc ctcacatctt      240

taacttagta ttttacctag catttcaaaa cccaaatggc tagaacatgt tta             293


<210>  4538
<211>  436
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (91)..(91)
<223>  n is a, c, g, or t

<400>  4538
taaataatac gaatatgcca acattatata atcattgctt tctgcaactg tttactataa       60

tttcaaaatt aatatcctat taactgttcc nataaattat caaatttggc aagtgtatta      120

ctagcaggag atggacctta aattatgaca actttatatt ttttgatagc atctcttgaa      180

aaagaatttt aatgattcta ataagaggtt ctttttcttt tttccatttc cttgacaaat      240

agtactcatt taaaaactag agggctaggc ttagtggctc acgcctgtaa tctcagcact      300

ttgggaggct gaggcgggca gatcgcttga ggtcaggagt tcaagaccag cccgggcaac      360

gtggtgaaac ccggtctgta ctaaaaaaaa aaaaaaagaa aaagaaaaag aaaaaagaat      420

acccaggtgt ggtagt                                                      436


<210>  4539
<211>  341
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (26)..(26)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (28)..(33)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (35)..(36)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (41)..(42)
<223>  n is a, c, g, or t

<400>  4539
aatccgtctg ccttttgatg ccgtantnnn nnntnngtcc nnctctgctg gttgcgcagc       60

cacctcggga tactgcacac ggagaggagg gaaaataagc gaggcaccgc cgcaccacgc      120

gggagaccta cggagaccca cagcgcccga gccctggaag agcactactg gatgtcagcg      180

gagaaatggc tttgagctca gcctggcgct cggttctgcc tctgtggctc ctctggagcg      240

ctgcctgctc ccgcgccgcg tccggggacg acaacgcttt tccttttgac attgaaggga      300

gctcagcggt tggcaggcaa gacccgcctg agacgagcga a                          341


<210>  4540
<211>  422
<212>  DNA
<213>  homo sapiens

<400>  4540
attgggataa caactttcat caccaatcat tggacttttg tgaagtcgac accagctaag       60

gctgcttaaa ataagttctg atcattatat aagaagggaa atgcctggca gacaccatgt      120

aagttataag tgtctgtctt atctttacta cacatattgt aacaaattca atatcctagt      180

cttcatttgt atgaatggtt tgtattgtac atagtttaac caagtgttat ttgagctgct      240

tattaatatt aacttgtact tgtctctctg cttgttattg gttaagaaaa aaggatatga      300

ggaattcatt ttatcaatgt agctgtgaag gccattaaaa agacaaactt aatgtacaga      360

gcattttatt cagatcaagt attgttgaaa gctatacata tacaacatta cagtctgtct      420

gt                                                                     422


<210>  4541
<211>  538
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (47)..(47)
<223>  n is a, c, g, or t

<400>  4541
ttcgccattc aatctctgtg ctgcagtaag agcaatctta aacagtntaa atcacacaca       60

cacacacaca cacacacaca cacacacaca caagtccctc aggaaaaatt ccaagctctt      120

gagaagatca catgagcccc ttcatgacct ggcgcttgct tatttcttcc aggacttctc      180

tcacttctat ccagctattc ccgtcagcaa atgaacctcc aaagcagcac atggagcact      240

gcatagacta tttcctcagt gcgtaactcc tccctgtctc ctctttacct gagtaacttg      300

tactcatcct tcaatactcc aactgaattt tacttaccct gaaaagattt ccatggctat      360

ccaccacccc cctgcctgtg agactgagtt aggtgccctt tttcatgtct ttcccccatc      420

acggcactta ccatactgcg ttgtaattgc ctgtgtactc gtctgtataa ctactagact      480

gtaagctcct tgagggcagg gactgtgtct atcttgttca cagttgtatc cccagcac        538


<210>  4542
<211>  513
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (392)..(392)
<223>  n is a, c, g, or t

<400>  4542
tggtttagct actctcttcc atcttccacc caactgcaag aggactgtat gtctggaaac       60

aggtagtcag aatgtgcagc tctgtacagc cattctaaaa ctggcctttc caccgcaatt      120

cataggaagc atgtacatgt ttcctttgct gtatgcactt ttccagtctg cagaagcggg      180

gatttttgtt ttaatctata aaatgtatgg aagtgaaatg ttgcacaagc gagatcctct      240

agatgaagat gaagatacag atatttctta taaaaaacta aaagaagagg aaatggcaga      300

cacttcctat ggcacagtga aagcagaaaa tataataatg atggaaaccg ctcagacttc      360

tctctaaatg tggagataca caggagcttc tntcttgctg aaatattgct tcatatttat      420

agcctgtggt agtgcacatg gttaacataa aagataacac tggttcacat catacatgta      480

acaattctga tctttttaag gttcactggt gta                                   513


<210>  4543
<211>  455
<212>  DNA
<213>  homo sapiens

<400>  4543
acatgatttt ctcatttcgg gaggaactct gttgcttcgc ctggacaaga aggaaaatgc       60

tgatttcctc cttgggtaga aagagggagc gagggcaaat ggggagtaga gagaaaacag      120

gcgagaacaa gcactctaat tccagtgggc tttaaaataa gacaaaatca gctttacaac      180

aatccctaga ggctcgacca cagaataatg ccagtcacca ccctgaacgc acaatctcca      240

gtgcaggatc taatgactgt acatattatt gttattatta ttattgttat tattgttgtt      300

ctgtaaacat gttgcacaag cttagccttt ttgcgttctg ttgtgtgtgg ctgtaaaacc      360

ccatgctttg tgaaatgaga atcttgacat ttttcttgtg aaatttggaa aatgtgatca      420

attgaaatca actgtgtttt gtgttctcta tgtca                                 455


<210>  4544
<211>  524
<212>  DNA
<213>  homo sapiens

<400>  4544
ctgtgtgtga attcctttag actaagggca ggaagacttc cagctttctc tttgttcttc       60

aatgtgaaac tgagaccaag tctctctaag acaaatgcag tgtatttaat gtttgtaagc      120

aattctaagt gagatgtttg gcaagaaatc ccctaactga tttccatcca aacctacctt      180

atagagcaca atattaagtg ttgtacaatt actgtgagaa ctgtgaatat gtgtaacttt      240

tttttagtat ttgcccgggg ggaaaaagat attgtattat catatatgct ttttttgcaa      300

taaggattta ttctcagaac accaagtaaa tctatctcta tataaaaaat atatgtaata      360

tatacatatt caaagtatat acagagcctg ttttaaaaaa tacagtatta tttagtaaaa      420

ttatctgttc tatggaccaa atgtaaaata tttataaatg aagatgcatt ttaaatgtct      480

ataaatggtg tcataactag agcacgggcg ttatgtaagt ttct                       524


<210>  4545
<211>  114
<212>  DNA
<213>  homo sapiens

<400>  4545
ttttaccatc tttatccaaa tttatcatat tgatggtagg actaacaggc tttttagaag       60

ctggctttaa ctttgagtct caagctacaa tgctgttggg cagcctggtc ttcc            114


<210>  4546
<211>  482
<212>  DNA
<213>  homo sapiens

<400>  4546
ctctggtgac caagatatca acgtggtttc tacatatatc tccaaaatga aagtaattta       60

tccagcagtt gaaggtcgga tcaagttttc cacaggaagt cactgccatg gaagcttttc      120

tttaatattt ctttcacttt gggcagtgat ctttgtttta taccaatagc caaaaattct      180

ccttgccttt aatgtgtgaa actgcatttt ttcaagtgag attcaaatct gccttttagg      240

acctggcttt gtgacagcaa aaaccatctt tacaggctcc tagaagctga aggttagagc      300

attataaaat gaagagacag acatgattac tcagggtcag caacctagtg agttagaaaa      360

aaaattaaca tagggcccta taaggagaaa gccaactatg ttaagtttac gtgtccaaat      420

tttaatgaaa ttttactaac aattttaaac catatttttc ttcttcatat ccatttctaa      480

tc                                                                     482


<210>  4547
<211>  297
<212>  DNA
<213>  homo sapiens

<400>  4547
gaaagcacta tgaatttgtc catttaaaaa tgatctgtag tttttttggt gctataacat       60

tctgacacat atcattctgt gattaaatct ccagcttact ataaatgata tctatattct      120

aaagagctac ttctaattat tccaatatga ccttaaggaa aagtaaggga ataaattttt      180

gtctttgttg gagtgaagca tttaaaagag taagggtaaa aaagataaag tcctgaacct      240

ttcaaaatgg aaaattaatt ctaaacttag aaatatgctt ctgcctattg ctgatac         297


<210>  4548
<211>  495
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (454)..(454)
<223>  n is a, c, g, or t

<400>  4548
aaacttgaat gctgtgtcta tccaatgcca aaatgctcag aagaaaagtg aataattcag       60

tcattcatct ggatgtagtt ttctgtgtaa tctcaaatat ctgaatattg aaaaaactag      120

gttgctaact tttttcattc cttatgcaaa tgtttagcat catagtgctg tttcagatac      180

agatctgttt catcaaatat cctcaattac aagtctaaga cagttatatg taaagaaaat      240

gtattatttt agatgaacaa tgtggataac tgaactaaaa cgatatttgt gaactttgct      300

ataatgaaat cttttatttt tatagctcag gtattgtaat tagcactaat tgcagcagag      360

actgaaataa ttattgacac cgtagagtac catagagtag gttgaactgg ccagacctag      420

acaatgaaga aaacacatac tgtttactta gganacattt tcttagtcgt gtgtatagtc      480

ctaaatttcc ccaaa                                                       495


<210>  4549
<211>  582
<212>  DNA
<213>  homo sapiens

<400>  4549
tgagaccaca ccatttctgc taagccaata ttctctagaa tgagcacaaa acaaatcgaa       60

taacagctaa acaaatcgaa taacagctaa acgaatcgaa taacagcttt tgtacatcaa      120

catcaagaag gaatacgcct gagagagatc agagtatata gatgaatatg aacaagaatg      180

gaacattcac ttgtcaacgc actttctaaa tctagatcag cagagatggg agtgattttc      240

tggaaagaga tgtgatcatg gattaaacac cagctcattg gaaactcatt ggatgagatc      300

agaaaacgtt catgaaaaat catattcagg aaataaggaa gaggaatata aatgctctag      360

agttaacatg taaaatatat acgtactgag gtttgtaaac tgtccttttt aaatcaaact      420

gaaaacaaaa agctttaacc tttcaacaga atttttaaaa aggcagttag ttctaaatta      480

ttcctatctc aatagccaag aggctgatca agcgtcattt attgaggaag catcttagaa      540

aatgcctctg aatgttttca taggagccgt gacctttggt tc                         582


<210>  4550
<211>  335
<212>  DNA
<213>  homo sapiens

<400>  4550
cagacacaca gccaaagcac aaagtcactt agaaaattgg aattgtacca tggaacttca       60

taatagattc tctgggagca gacgagaagc atcatcttaa aaccacagct cttgccagta      120

catttttctt tacaactgtt tttggtacaa ctgcactgaa gtgttatttt tgatgttgag      180

ctttcttctt ttagaagcat attgcatggc tacattttct taaaaaaaaa aaactgtgac      240

cttatgctac ttcattgtga ctggaagact gctggagaat tcagaaagta tatagtattt      300

ctgtgttaga gcaagctggc tttgtagcac atttt                                 335


<210>  4551
<211>  91
<212>  DNA
<213>  homo sapiens

<400>  4551
aataacacgg cccaataact ctttgtgttt atggagtgtt gttttcttag aataatggag       60

atgcagatat agataccata gtcaaggtac c                                      91


<210>  4552
<211>  150
<212>  DNA
<213>  homo sapiens

<400>  4552
agaaatatta ttccagcata gcaggaaaac aaacaaaagt attggactgt cggaggtgag       60

cctgtgcgtc tgtaaccctt tgtgactcct gagcgtgcgc tgtcttctag gttaactcac      120

gaagtacatt ctctgtctta ctgatactgt                                       150


<210>  4553
<211>  443
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (269)..(269)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (275)..(275)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (282)..(282)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (406)..(406)
<223>  n is a, c, g, or t

<400>  4553
aagctatgtg tatcttctgt gtaaagcagt ggcttcactg gaaaaatggt gtggctagca       60

tttccctttg agtcatgatg acagatggtg tgaaaaccat ctaagtttgc ttttgaccat      120

cacctcccag tagcaatttg ctttcataat ccatttagca atccaaggcc tctgttgaaa      180

agataatatg agggagaagg gaacacattt ccttctgaac ttacttccct aagtcacttt      240

ccttatgtat catctaatac aatgatggnt tgagntgaaa antacagaag gggtgtttga      300

gtattcagat ttcataaaac acttccttgg aatatagctg cattaacttg gaaagaagcc      360

tgttgggcca gaagacagaa actccaactg gcaaaaaagc aagcantcta agaaaaaaaa      420

ccaccaaagt tcttgaattt act                                              443


<210>  4554
<211>  399
<212>  DNA
<213>  homo sapiens

<400>  4554
aagagttccc ctttgcttta ggagtgcaga ctctgcctca aacttgtgat gaacccaaag       60

cccacaccag cttccaaatc tccctaagtg tcagttacac agggagccgc tctgcctcca      120

acatggcgat cgttgatgtg aagatggtct ctggcttcat tcccctgaag ccaacagtga      180

aaatgcttga aagatctaac catgtgagcc ggacagaagt cagcagcaac catgtcttga      240

tttaccttga taaggtgtca aatcagacac tgagcttgtt cttcacggtt ctgcaagatg      300

tcccagtaag agatctgaaa ccagccatag tgaaagtcta tgattactac gagacggatg      360

agtttgcaat tgctgagtac aatgctcctt gcagcaaag                             399


<210>  4555
<211>  177
<212>  DNA
<213>  homo sapiens

<400>  4555
caaacggact gatgtcactg gctcaatagc tttagcaatt ggattttctg ttgcaattgg       60

acatttattt gcaatcaatt atactggtgc cagcatgaat cccgcccgat cctttggacc      120

tgcagttatc atgggaaatt gggaaaacca ttggatatat tgggttgggc ccatcat         177


<210>  4556
<211>  590
<212>  DNA
<213>  homo sapiens

<400>  4556
tggtgagatc ccctcggagc agcaccctgg ggccagcgct tctccacctt gtgcttcgcc       60

gccagtctca gcgccggcct cctgggactt tggtgtgccg cagcggatgg cgggcggcgg      120

tggtccgggc agtggcggca gcggcgccgg cagctcgggc tccagcccga gcagcgcggc      180

ctcggctttt ctgggcaact acccctggta ccaccagacc tcgggatccg cctcacacct      240

gcaggccacg gcgccgctgc tgcaccccac tcagaccccg cagccgcatc accaccacca      300

ccatcacggc ggcgggggcg ccccggtgag cgcggggacg attttctaac cccagggaga      360

actcgccaga gactgagagc agagaccact tatcctcatt gcttaccccg agccggggtt      420

ccctcctccc ggcccgctgc cgccacccac ctctcctgca ggctgcgacc tgcagtggcc      480

cgtctcaggc cctgctcact cccggggcca ccaaacgggc ccctctctcg ggggaaccgg      540

acagcagctt ggcaaaggcc tccctaaaag gccgcatttc tgacctgagc                 590


<210>  4557
<211>  437
<212>  DNA
<213>  homo sapiens

<400>  4557
taacccaaaa ctgccgattt caggggcggg tgcattgtag ttattatttt aaaatagaaa       60

ctaccccacc gactcatctt tccttctcta agcacaaagt gatttggtta ttttggtacc      120

tgagaacgta acagaattaa aaggcagttg ctgtggaaac agtttgggtt atttgggggt      180

tctgttggct ttttaaaatt ttcttttttg gatgtgtaaa tttatcaatg atgaggtaag      240

tgcgcaatgc taagctgttt gctcacgtga ctgccagccc catcggagtc taagccggct      300

ttcctctatt ttggtttatt tttgccacgt ttaacacaaa tggtaaactc ctccacgtgc      360

ttcctgcgtt ccgtgcaagc cgcctcggcg ctgcctgcgt tgcaaactgg gctttgtagc      420

gtctgccgtg taacacc                                                     437


<210>  4558
<211>  278
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (31)..(31)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (34)..(34)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (39)..(39)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (45)..(45)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (48)..(48)
<223>  n is a, c, g, or t

<400>  4558
agtccaggtg acagttcctg aaggggcttc ntgnggaana taccntangg aggctccagc       60

ccagcccagg ccctctcccc ctaccctggg caccagatct tccatcaggg ccggagtaaa      120

tccctaagtg cctcaactgc cctctccctg gcagccatct tgtcccctct attcctctag      180

ggagcactgt gcccactctt tctgggtttt ccaagggaat gggcttgcag gatggagtgt      240

ctgtaaaatc aacaggaaat aaaactgtgt atgagccc                              278


<210>  4559
<211>  593
<212>  DNA
<213>  homo sapiens

<400>  4559
aaaggtctcc agattctagg tcagaccctc aaagccagca tgagagaatt gggcctcctg       60

atattctttc tcttcatagg ggtcatcctt ttctctagtg ctgtgtattt tgcagaggcc      120

gatgagcgag agtcccagtt ccccagcatc ccagatgcct tctggtgggc agtcgtctcc      180

atgacaactg taggctatgg agacatggtt ccgactacca ttgggggaaa gatagtgggt      240

tccctatgtg cgattgcagg tgtgttaact attgccttac cggtccctgt cattgtgtcc      300

aatttcaact acttctacca ccgggagaca gagggagagg aacaggccca atacttgcaa      360

gtgacaagct gtccaaagat cccatcctcc cctgacctaa agaaaagtag aagtgcctct      420

accattagta agtctgatta catggagatc caggagggtg taaataacag taatgaggac      480

tttagagagg aaaacttgaa aacagccaac tgtaccttgg ctaacacaaa ctatgtgaat      540

attaccaaaa tgttaactga tgtctgattg aaacctatta ccgtactcac agc             593


<210>  4560
<211>  139
<212>  DNA
<213>  homo sapiens

<400>  4560
gaaataccca aagataatag tgcatagctc ctttcagcct ctagccttca ctcctgggct       60

ccaaaagcta tcccagttgc ctgtttttca aatgaggttc aaggtgctgc tttgcatgcc      120

tgccaaccca tggaagttg                                                   139


<210>  4561
<211>  375
<212>  DNA
<213>  homo sapiens

<400>  4561
gtgtgatccg ggtctggttt caaaacaagc ggtgcaagga caagaagcga agcatcatga       60

tgaagcaact ccagcagcag cagcccaatg acaaaactaa tatccagggg atgacaggaa      120

ctcccatggt ggctgccagt ccagagagac acgacggtgg cttacaggct aacccagtgg      180

aagtacaaag ttaccagcca ccttggaaag tactgagcga cttcgccttg cagagtgaca      240

tagatcagcc tgcttttcag caactggtca atttttcaga aggaggaccg ggctctaatt      300

ccactggcag tgaagtagca tcaatgtcct ctcaacttcc agatacacct aacagcatgg      360

tagccagtcc tattg                                                       375


<210>  4562
<211>  488
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (46)..(46)
<223>  n is a, c, g, or t

<400>  4562
aaatccctat tcttggaaaa tacacaataa agtattttga ggtaangggc cataatgtat       60

gcaatctact ctcaaaaaat tcagaaacat atatttgtgt gcatttgcat gtgcaacagt      120

acacacaaac atacataaag agagcaattg ataaggcaaa taaggtaaca tttaacaata      180

atctgataca cataaataga gaaagagcaa ttgataaagt aaatgaggta aaatttaaca      240

ataatctgag caaaaggtat atgtgttttc tttgagacag tctgattctt gcaacttatt      300

ctgtaagttg gaacttattt ccaaacatga ttgaaaaaaa accccgcact tggcaacttc      360

ttctcttttt cagcctagaa atgtctgtgt taagtggttt tttatttatt gttgttgttt      420

gttgttattg ttgttttgtt gccaggctcc aactcacaaa atacgagttt aaaaactgcg      480

ttgttatt                                                               488


<210>  4563
<211>  207
<212>  DNA
<213>  homo sapiens

<400>  4563
gaaagcaact tagaactcga gattcacctt tcgtttccct ttccccaaaa gtagcgtaac       60

caacatttaa gcttgcttaa aaacgaaaac caaccgcctt gcatccagtg ttcccgattt      120

actaaaatag gtaaccaggc gtctcacagt cgccgtcctg tcaagagcgc taatgaacgt      180

tctcattaac acgcaggagt accggga                                          207


<210>  4564
<211>  509
<212>  DNA
<213>  homo sapiens

<400>  4564
gtcattttgg tctaaggttg ccattgctgc taaaggttac cgatttcaaa gtccagatac       60

caagcatgtg gatatgttta gctacgttta ctcacagcca gcgaactgac attaaaataa      120

ctaacaaaca gattctttta tgtgatgctg gaactcttga cagctataat tattattcag      180

aaatgacttt ttgaaagtaa aagcagcata aagaatttgt cacaggaagg ctgtctcaga      240

taaattatgg taaaattttg taagggagca gacttttaaa gacttgcaca aatacggatc      300

ctgcactgac tctggaaaag gcatatatgt actagtggca tggagaatgc accatactca      360

tgcatgcaaa ttagacaacc aagtatgaat ctatttgtgg gtgtgctata gctttagccg      420

tgtcacgggc atcattctct aatatccact tgtccatgtg aaacatgttg ccaaaatggt      480

ggcctggctt gtcttctgaa cgtttggtt                                        509


<210>  4565
<211>  516
<212>  DNA
<213>  homo sapiens

<400>  4565
tcagccatgc ttggatactc acattaggag gaccatgtgg ttggaaggat agactgcccc       60

ctacctccca ccaccaccat gaagtttggt gacttgaggc tggagctccc tctgttacct      120

ttccatctag caagttccca aaggcaagac tctctctgat ggtcactttg tggtctgtgc      180

tttcagaaat acaggaatct gatatcaaca tatcctaggg tttctaccaa tctctgttga      240

aagaagccag ggtttgccac tgtgaagctt gatttctgct ggtgacttct gaccataagc      300

tagaaccatg gtcgccactg ttttccctct gtagtttctc aagtgaacac tctcaggata      360

cccagttccc tcatagcctc tgttctcaga gaattggagt tggcccaaga aacataaaca      420

tataaccacc catatctatc ctggattctg aactcttcaa tttggagtga ctaacacaag      480

ttgttatcta aacctttaaa cctatcttcc aggcag                                516


<210>  4566
<211>  539
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (249)..(249)
<223>  n is a, c, g, or t

<400>  4566
gcctcttcct ttgtatccag tactaggaga gtactcactg gacagctgtg atttgggact       60

gctttccagc ccttgctggc ggctgcccgg agtctactgg caaaacggac tctctcctgg      120

agtccagagc accttggaac caagtacagc gaagcccact gagttcagtt ggccggggac      180

acagaagcag caagaggcac ccgtagaaga ggtggggcag gcagaggaac ccgacagact      240

caggctccng cagcttccct ggagcagtcc tctccatccc tgggacagac agcaggacac      300

cgaggtctgt gacagcgggt gccttttgga acgccgccat cctcctgccc tccagccgtg      360

gcgccacctc ccgggtttct cagactgcct ggagtggatt cttcgcgttg gttttgccgc      420

gttctctgta ctctgggcgt gctgttcacg gatctgtgga gctaagcagc cttagatagc      480

agcagaaggc tttttggatt ctcctccttg aaaagattct cagttaccaa acgtctcca       539


<210>  4567
<211>  366
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (235)..(235)
<223>  n is a, c, g, or t

<400>  4567
tatgcgtgac cgttaagata ttatcattta ggtgaaggtt tcaactcaaa accacccaac       60

ccggtggtta acgatttaat acatataacc aaaccggcag cgtttagagt tgggatatac      120

atttaaacat tttcctggtt aaggttccca agagagtgta aaggttttag cagaaagcaa      180

aatatcttgc atctttatgg aagtttaaag catgtttgca aatattgcag cccantgaaa      240

gaatttgcat gtacaggaaa gttgtggatg gagacggttt gtggaatttt aagtgctcat      300

tgtagtaaac ttttgctttg tagatttgaa ggtacagact tatacaggca agttcacaaa      360

atcatg                                                                 366


<210>  4568
<211>  518
<212>  DNA
<213>  homo sapiens

<400>  4568
atgtgttctc aaatgattgt ttactatatt acatttctgg atgttctagg tgcctgtcgt       60

tgagtattgc cttgtttgac attctatagg ttaattttca aagcagagta ttacaaaaga      120

gaagttagaa ttacagctac tgacaatata aagggttttg ttgaatcaac aatgtgatac      180

gtaaattata gaaaaagaaa agaaacacaa aagctataga tatacagata tcagcttacc      240

tattgccttc tatacttata atttaaagga ttggtgtctt agtacacttg tggtcacagg      300

gatcaacgaa tagtaaataa tgaactcgtg caagacaaaa ctgaaaccct ctttccagga      360

cctcagtagg caccgttgag gtgtcctttg tttttgtgtg tgtgtgttct tttttaattt      420

tcgcattgtt gacagataca aacagttata ctcaatgtac tgtaataatc gcaaaggaaa      480

aagttttggg ataacttatt tgtatgttgg tagctgag                              518


<210>  4569
<211>  538
<212>  DNA
<213>  homo sapiens

<400>  4569
tataagcaag cttttcccag caccatcaga gaagagtcat gaagaaacag acagtaccaa       60

ggaagaagca gctaagatgg aaaaggaata tggaagcttg aaggattcca caaaagatga      120

taactccaac ccaggaggaa agacagatga acccaaagga aaaacagaag cctatttgga      180

agccatcaga aaaaatattg aatggttgaa gaaacatgac aaaaagggaa ataaagaaga      240

ttatgacctt tcaaagatga gagacttcat caataaacaa gctgatgctt atgtggagaa      300

aggcatcctt gacaaggaag aagccgaggc catcaagcgc atttatagca gcctgtaaaa      360

atggcaaaag atccaggagt ctttcaactg tttcagaaaa cataatatag cttaaaacac      420

ttctaattct gtgattaaaa ttttttgacc caagggttat tagaaagtgc tgaatttaca      480

gtagttaacc ttttacaagt ggttaaaaca tagctttctt cccgtaaaaa ctatctga        538


<210>  4570
<211>  544
<212>  DNA
<213>  homo sapiens

<400>  4570
tactgcttct gttcatcgtg tatgcgtaca tgtatattct ctggaaggct cacagccacg       60

ccgtccgcat gattcagcgt ggcacccaga agagcatcat catccacacg tctgaggatg      120

ggaaggtaca ggtgacccgg ccagaccaag cccgcatgga cattaggtta gccaagaccc      180

tggtcctgat cctggtggtg ttgatcatct gctggggccc tctgcttgca atcatggtgt      240

atgatgtctt tgggaagatg aacaagctca ttaagacggt gtttgcattc tgcagtatgc      300

tctgcctgct gaactccacc gtgaacccca tcatctatgc tctgaggagt aaggacctgc      360

gacacgcttt ccggagcatg tttccctctt gtgaaggcac tgcgcagcct ctggataaca      420

gcatggggga ctcggactgc ctgcacaaac acgcaaacaa tgcagccagt gttcacaggg      480

ccgcagaaag ctgcatcaag agcacaggtc aagattgcca aggtaaccat gtctgtgtcc      540

acag                                                                   544


<210>  4571
<211>  216
<212>  DNA
<213>  homo sapiens

<400>  4571
gcagagactt ctagctggac aacctacaca aaccttagcg tctagagtca ctctaacctt       60

gctaaggaag gatgcagagt tccctagaga gacttgcact gatggggtga cttctgcttt      120

ggtccttcca ccacccccac caagtaaacc acctgtggca gcggctgttc cctcaacctg      180

ctacttctgc gtccataagg gtcctgcacg ttgcct                                216


<210>  4572
<211>  188
<212>  DNA
<213>  homo sapiens

<400>  4572
atctccagga ggcaggtaga gcagttctga ccgagaggat agactgctgt tgctgtcttt       60

ccccagctct gaactagttt taaggtagct taggatgaaa aatggagaat gattgggggt      120

tccaaaccac tttcttctcc cttggcttat atctcttcac catttggtgg tcaactgtgg      180

gcctaccc                                                               188


<210>  4573
<211>  498
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (223)..(224)
<223>  n is a, c, g, or t

<400>  4573
aattctttgt atcactttga agtacatata tttaaaggga agatggatac aatttgtttt       60

tattatataa atctaggtaa ggtgaaatgc ttttgtcaac aaaaatacag tgtagtgaat      120

tttatatttg tcacttgatt aggtaaactg aaaactaaca atagaaatat tattttactg      180

cattgaaata ccatgaactt tcagacttgt tagttctaca agnnagttgt gctaccttaa      240

ttttgtgttt ccagaaataa aaattaacct tagttatgct gtcattttta actaataaaa      300

aaagtataat tcataaaact tttggcttta taagataatt ataaaattat atattttttt      360

ctgtttttgt ggggttggga aaacattttc ttatttctat tcactcttca aatgcaggtc      420

tcataatatg tgtcaatgat ataagatgat ggaagacttt gtaataaaaa catatgtcat      480

tatcttcaat ttgttcaa                                                    498


<210>  4574
<211>  148
<212>  DNA
<213>  homo sapiens

<400>  4574
aagagaagaa gcttaaagtc ctggctaatt gtgtggtcat tggaaaactc tgcaatacaa       60

taattttctt tattttcttt ttctttttta aattcttagt gtaattgaaa cgtgctctat      120

agatattgac tctgtgttcc ctctttta                                         148


<210>  4575
<211>  405
<212>  DNA
<213>  homo sapiens

<400>  4575
aatatggcca ttcttctgtc acatgccaat tcagttgtca atcccattgt ctatgcttac       60

cggaaccgag acttccgcta cacttttcac aaaattatct ccaggtatct tctctgccaa      120

gcagatgtca agagtgggaa tggtcaggct ggggtacagc ctgctctcgg tgtgggccta      180

tgatctaggc tctcgcctct tccaggagaa gatacaaatc cacaagaaac aaagaggaca      240

cggctggttt tcattgtgaa agatagctac acctcacaag gaaatggact gcctctcttg      300

agcacttccc tggagctacc acgtatctag ctaatatgta tgtgtcagta gtaggctcca      360

aggattgaca aatatattta tgatctattc agctgctttt actgt                      405


<210>  4576
<211>  282
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (245)..(245)
<223>  n is a, c, g, or t

<400>  4576
aaatgtcctc aactgtcatc attctatgtt tactttctcc caatcacatc acctgaggta       60

gaagagattt ttcagttgct atttctcttc gtaatgaatt ttctttacat cctgtccaca      120

ctgctggaga tactaagtcc caacctaaat gatggaagga gcatctcccc tcttgtctgt      180

ggaagatatc acatgaacta cctaattttc aagcatggat ctccatattt caaaggaaag      240

ttttnaaaat gtttttaaaa cttcaaatat ctcaccacag tg                         282


<210>  4577
<211>  557
<212>  DNA
<213>  homo sapiens

<400>  4577
cccttgaaat tcattagttt gtcataaagt tttaggaaag gtaggacccg gaaagaagtt       60

ctaattagtt gtctaaatat ttttcagtga gccaagaaat tcaccatgaa aaaacaagaa      120

taacaaatag aagggaagag ataggatggg aaagctaaca aattaaagtt ttggcaaaaa      180

ggaatatatg taaatagcta attatttact tttgtgctta ctttatttag attatttcta      240

tcagttacaa tctttttcta gttaagtgta cctaatttat ggaatgggtg ctatcctgtt      300

tatgtgtgtc ttggtttttc ttggctacag aaaaactgtt gcagggcaac actagtttga      360

tatttgattt actctccaat gagactcaat ggctgggccg tggtagactc atagttcctc      420

ttgttcttta ttaaattcat cctgctaatt agatttctag tgacttgtaa catgtagttt      480

acactgaatt gcaattacag atgcatacaa ctactatact agaaaaaatt gtcatttctg      540

atgtgccaat aaatgat                                                     557


<210>  4578
<211>  535
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (37)..(37)
<223>  n is a, c, g, or t

<400>  4578
gcacattaat ttgcagtggc tgcttcatat gaggagntat ggtggacagg ctaatttttc       60

cttgaaaatg tggcttcttc aactcctttc aaatttagga tggaatactt cctgaaataa      120

aactgggctt tatgcaggat tctctttgaa aattcttgta tgtccagaac aaaagataaa      180

actaattgta ttcctcacat tcacaatccc cattggtctg aagtcacgta gcacagagca      240

tctatagcac atagtgttta aagactaatg aatgcaaaaa gataaaatct tcaactaatt      300

tttgaattgt ttctcatata tgctactaga aaatgccttg ttgatgaagc acattttggg      360

tagttgaggt cttttgtttt cgcctttagc tttctaagct ttcttacaat gtggactgat      420

tactgtaaca tttcacgtgt aaaataactg gatattcttt atatactgga aataacctgt      480

gaatccaata tttcactaag tgttttaact tttgtgtata tatctctcat caata           535


<210>  4579
<211>  569
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (261)..(261)
<223>  n is a, c, g, or t

<400>  4579
acacacctac ttttactgac tattcaacat aaattgaatc tttaacatga ctttaaaggc       60

tatttacaaa gctgttttaa agtttttcaa acatgataga aattttctaa attttagtaa      120

gagagaagct tttaaaacag tacattcctg aataaaacaa caatattgta tcttaatcaa      180

ggctgtctga tgcagatgat tgcatttttt ggcaaatttt agaagcattt attgctttgt      240

ctttagtgta acaagatcac nggattaaat ataaacattc aggttaatta tctagatttt      300

tgtccacagt atatgatcca tccagacatt tgcaaacgtc aggagaaaaa tgtgaattat      360

ttatccagat gcatgtcatc tcaaggacaa agcctgtgaa agtacaagtg agatggttgc      420

attgtagtat gcattaatct ttcaatgtag tggtgtaaaa atgcagtgct aaactaatga      480

agcaggtgac tgcagccttt ggctcaagct cacaactctg ataactgtca gtgcctgagg      540

ttgtgattgg tgacattctg acactgccc                                        569


<210>  4580
<211>  478
<212>  DNA
<213>  homo sapiens

<400>  4580
gaaacctaat aatctctccg agggagaaag gggttctctg cggtattcca gtgaaactca       60

tttgatggtt tcttttgaat tagttagaca cttgaacggt gttttttaga actcttcatg      120

ttaaagacgt ggtttagtac tcccaatgct gtgtatcatg acactatctt cgtctgtagt      180

atttatgatg ttaagataat gcgggtaaca gacaatataa tagccccgac cttaaacgaa      240

gcttttgtac tgcagaatac atctggctgt gtgatttttt tttttaagca agatttgttt      300

tactataaat aagtggatta tttcaatgca ggcaaaattg tgaagttctg ttgggaaaga      360

tagcatgctt ttcgtgtgca agtacctgtc agtaataagc cttttttttt ttttttttta      420

atttaaatgt ttgtagctgc tatgtggaca gttgttttct agtgtggtct gtagccca        478


<210>  4581
<211>  445
<212>  DNA
<213>  homo sapiens

<400>  4581
aagccctagg aaaagcagcg cagatagcac ttcagctcgg ccatctcaga tcccaactcc       60

agtgaataac aacacaaaga agcgagattc caaaactgac agcacagaat ccagtggaac      120

ccaaagtcct aagcgccatt ctgggtctta ccttgtgaca tctgtttaaa agagaggaag      180

aatgaaacta agaaaattct atgttaatta caactgctat atagacattt tgtttcaaat      240

gaaactttaa aagactgaaa aattttgtaa ataggtttga ttcttgttag agggtttttg      300

ttctggaagc catatttgat agtatacttt gtcttcactg gtcttatttt gggaggcact      360

ctcttgatgg ttaggaaaaa aatagtaaag ccaagtatgt ttgtacagta tgttttacat      420

gtatttaaag tagcatccca tccca                                            445


<210>  4582
<211>  55
<212>  DNA
<213>  homo sapiens

<400>  4582
agagaaaata aactacccct cctattcaga agtttatagt ttatggagat ggatg            55


<210>  4583
<211>  501
<212>  DNA
<213>  homo sapiens

<400>  4583
attttggcgt gtttaaccat taagaaatgc tgtattctta aatatgaaac agttaatcta       60

aagtcttatt atttcttcta gtaaaataaa atattgttag attagttctc attaaattta      120

ttatatgcta aagaataaaa ctccagttag atttaaaaaa atcccattta caagcattgc      180

acctttaaga agaaaacaaa tatgacagta tggtagctat acttgtgatg tctgacgcat      240

gatggcctat ggttttaaaa atagtattgt ggaatatatt tttgggtaat aagaatggtt      300

gagtgcaaca tcatgtatta atatcaaatg aaagacaagg gtgctgtatc tttgattatt      360

tatcaaaaaa gtataaatct tttaaggaaa atgttagaat tttaaagttt ttttttgatt      420

gttgaagcat ttatcttgtt gatttcttac aaaagaaaaa ggacgatgtc agtcaagcag      480

cactttttca gaatatacag a                                                501


<210>  4584
<211>  265
<212>  DNA
<213>  homo sapiens

<400>  4584
ctgggtcatt ttgaccttgc tttgttaata atatctttaa aaacaaagac aatccttaaa       60

gctttgctcc tcacacatta ccttctaatt atagtttgaa aatagattcc ctacacatac      120

atacatatgt atgcacagat agggtcttgc tatgttgccc aggctggtct tgaactcctg      180

gcctcaagca atcctctctc ctcagcctcc caaagtgctg ggattacaag tgtgagccac      240

cacacctggc tccagaaatt ttatt                                            265


<210>  4585
<211>  415
<212>  DNA
<213>  homo sapiens

<400>  4585
gatcttttgt gactacaact tcttttgtaa ataatgatat atggtatttc catcgtcagt       60

taccgagtat agccactggg tatcactact ttgtgttaaa gtgccttcgc actttaagta      120

cattacttaa atgttgcttt tagctttgat aaattgaaaa tattttaatg tgttgtattt      180

ttgaaattga aaacactgta aaatagattg atgtgtcagc tatattaagt caacgtacag      240

tttgcttgag ttatagaaac cagcctgtca tcaaatgatt ctagttctag gactttgtag      300

gcttaactat aaaatatttc ctttcctctg ggtttaagtg attttattta agtcaactaa      360

ggggatttaa cagtggacta gaggtaataa gccacctcag tcaggattaa taatt           415


<210>  4586
<211>  391
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (109)..(109)
<223>  n is a, c, g, or t

<400>  4586
atggaagccc tggaaaatcg cctgagatac agatgaagat tagaaatcgc gacacatttg       60

tagtcattgt atcacggatt acaatgaacg cagtgcagag ccccaaagnc tcaggctatt      120

gttaaatcaa taatgttgtg aagtaaaaca atcagtactg agaaacctgg tttgccacag      180

aacaaagaca agaagtatac actaacttgt ataaatttat ctaggaaaaa aatccttcag      240

aattctaaga tgaatttacc aggtgagaat gaataagcta tgcaaggtat tttgtaatat      300

actgtggaca caacttgctt ctgcctcatc ctgccttagt gtgcaatctc atttgactat      360

acgataaagt ttgcacagtc ttacttctgt a                                     391


<210>  4587
<211>  482
<212>  DNA
<213>  homo sapiens

<400>  4587
tcacttaagg gatcttccag aagatatcta aaagtctgta ataagcttag aagttcagat       60

aaatctaggc aggatactgc atttttgtgg ttttaaaaaa gtccttagga cagactgaat      120

tatcataact tatggcatca ggaggaaact ttaaaatatc aaggaatcac tcagtcaccc      180

tcctgttttg ttgaaggatc aaccccaaat tctgggtatt tgagtacatg tgaatcatgg      240

atttggtatt caactttttc cctggatgct ttggaatcgt gtcttccatg ctccactggg      300

ttcaatttaa aataggagag gctttctctt ctgaaagatc cattttaggt ctttttcaag      360

aatagtgaac acatttttta acaaaataag ttgtaatttt aaaaggaaag ttttgcctat      420

tttattaaga tggaaatttc tttttaggct aatttgaaat ccaactgaag ctttttaacc      480

aa                                                                     482


<210>  4588
<211>  522
<212>  DNA
<213>  homo sapiens

<400>  4588
gcagcacacc aggagccatg agaagtgcct tggaaaccaa cagggaaaca gaactatctt       60

tatacacatc ccctcatgga caagagattt atttttgcag acagactctt ccataagtcc      120

tttgagtttt gtatgttgtt gacagtttgc agatatatat tcgataaatc agtgtacttg      180

acagtgttat ctgtcactta tttaaaaaaa aaacacaaaa ggaatgctcc acatttgacg      240

tgtagtgcta taaaacacag aatatttcat tgtcttcatt aggtgaaatc gcaaaaaata      300

tttctttaga aacataagca gaatcttaaa gtatattttc atataacata atttgatatt      360

ctgtattact ttcactgtta aattctcaga gtattatttg gaacggcatg aaaaattaaa      420

atttcggtca tgttttagag acagtggagt gtaaatctgt ggctaattct gttggtcgtt      480

tgtattataa atgtaaaata gtattccagc tattgtgcaa ta                         522


<210>  4589
<211>  370
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (166)..(166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (250)..(250)
<223>  n is a, c, g, or t

<400>  4589
atatactctt atatgggcta aaaagacccc atgaataaat agcaggttca gtagttgagg       60

agtggagttt agtaggtttg ttttcagtat aaattagata acatgtggag gtcacagcat      120

tttggaaatt gagtgtcccc aagtgagctt tgtttataaa ctttcnaaat gtcggaagtg      180

gacaggtttg ttaaatcttg tctgccagca cccttttctt cctttgttcc ttttcctctc      240

tgtgttattn gcctgcggca gccagtcctt catactagat agagttcaga taaagcaaac      300

gtttggcaaa aacatactgt ttgacctcct ccccctctgc ttatgaaggg gtagcatgat      360

tctgtgtttt                                                             370


<210>  4590
<211>  472
<212>  DNA
<213>  homo sapiens

<400>  4590
gaggctcatg ttaatatata cccaattact tcatttcagc tcatttttga aggtatccga       60

ggtcctggaa tagaaggtga cattgctatt gatgatgtat caattgcaga aggagaatgt      120

gcaaaacaag acctagcaac taagaattcc gttgatggtg ctgttgggat tttggttcat      180

atatggcttt ttcccattat cgtcctcatc tctatcttaa gtcctcgaag gtgaccttat      240

cctggcagag gctataaaag attcaccagg cactggcatg aagaaagagt ctttgtaaat      300

ggacattgaa caaacaaact accaaagatt cctccactga ctactgactc aaaaataaaa      360

taataaaaac aaattttttt aagcactggg gataaaaaga catcatggaa gtataactta      420

ttccagacta aacataaaag ataatcttga cctgagtaga gaagagacct tc              472


<210>  4591
<211>  446
<212>  DNA
<213>  homo sapiens

<400>  4591
aaggaagcaa tgtgtgtcag gcctctgtgc agtcaaccca gcctcctccc gccagtgcta       60

accccgtgtt gagcctgcat gctgacactg tggccgatct ggactctaga agtgctagtt      120

tgaaatatat ccattactgt catttccttt tgagcttgtg gacaagctga atgtcaggac      180

tgacttctcc agctcccagc cctgcggggg tgtccttggc atcccatcag cagaggagat      240

gcgtccctgt tgcattttgg cgtttggggc tttgggttta tccacatgag ctctgaacgt      300

ccgttatagt tagggtgatt ggaaggtctc catcactggg tgttttaaag gtgattcacc      360

accatttgtg aaaggaccaa cgtgctgata aacaggaccg atccgagtgc tacatgactg      420

tgcgtttgct atttcaatgg gcctga                                           446


<210>  4592
<211>  366
<212>  DNA
<213>  homo sapiens

<400>  4592
gattgtgaca cattcttagt agctagtgtc tgttctagtc actgcactgg agtctacgag       60

ccggaactcg ctatatgcac gtgtgtgtgt ccgtatgtaa gaaagtgtgc accgagtgac      120

tgaatggttg agatgaattg gaatgctgaa gactaacgaa gaaactagag actgatatcg      180

agcattctgc ccacctcgct ctgtatttaa ttaattgtgc tatatgttgc tttaacaacc      240

cattgagcag tcagggaatg tgagtaagct tgctgccaaa ggtaactagg aaagcattca      300

tctgctgcct ccttgttttt gctcctagag agtgaaaata caggcaattt tactgtgagt      360

gtttca                                                                 366


<210>  4593
<211>  142
<212>  DNA
<213>  homo sapiens

<400>  4593
ttgggtggag tttcgtaatt tcccagacta ttttcaagca acctggtcca cccaggatta       60

gtgaccaggt tttcaggaaa ggatttgctt ctctctagaa aatgtctgaa aggattttat      120

tttctgatga aaggctgtat ga                                               142


<210>  4594
<211>  441
<212>  DNA
<213>  homo sapiens

<400>  4594
gaagcacacg ctagcccgag aggatgtctt tccggccaat gccctcctgg aaatccggcc       60

attccaagtt tggctccatc atctcgacca caaaggggag gccacagtgc acatggatac      120

cttccaggtg gcccgcatcg cctactgcac cgccgaccac aacgtgagcc ccaacatctt      180

cgcctgggtc tacagggaga tcaatgatga cctgtcctac cagatggact gccacgccgt      240

ggagtgcgag agcaagctcg aggccaagaa actggcccac gccatgatgg aggccttcag      300

gaagactttc cacagtatga agagcgacgg gcggatccac agcaacagct cctccgaaga      360

ggtttcccag gaattggaat ccgatgatgg ctgaatgaac ttgagacgct tcagcaaagg      420

cagcattggt cacggagttc a                                                441


<210>  4595
<211>  494
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (424)..(424)
<223>  n is a, c, g, or t

<400>  4595
attgatgtta tcagacagag cactgactat gtactatcaa actatctaac aatctgcata       60

agtctgattc tatttctatg actttgaatt tagaatcact taaagctttt ataaagaatc      120

gataaattca cctgtatttg ttgttagaaa aaaactgggt gtctgtacat tttgtggtgt      180

aaaatatgta attgaagatt actattttaa gaagtcatca gtcatatcac tcacacagaa      240

ttttatttta catagttttg tgacttaatt acacatgaat ataaaatcta taattctata      300

tgaatatata gagatataga aacatctgaa ctggtaaaga ataactataa aatatgaaag      360

ctctaaattt aaaataaatt tagagataga atcatggtac attattgttt cagtattcca      420

tgtnaaaatt ttatagctta aatgtagtca gtgtttgatt aatgaaaaaa ttcttcatga      480

gtcagccttc aaaa                                                        494


<210>  4596
<211>  541
<212>  DNA
<213>  homo sapiens

<400>  4596
tctcccttgt acagccttat tttgttggtg ctttgcattt tgatattgct gtgagccttg       60

catgacatca tgaggccgga tgaaacttct cagtccagca gtttccagtc ctaacaaatg      120

ctcccacctg aatttgtata tgactgcatt tgtgggtgtg tgtgtgtttt cagcaaattc      180

cagatttgtt tccttttggc ctcctgcaaa gtctccagaa gaaaatttgc caatctttcc      240

tactttctat ttttatgatg acaatcaaag ccggcctgag aaacactatt tgtgactttt      300

taaacgatta gtgatgtcct taaaatgtgg tctgccaatc tgtacaaaat ggtcctattt      360

ttgtgaagag ggacataaga taaaatgatg ttatacatca atatgtatat atgtatttct      420

atatagactt ggagaatact gccaaaacat ttatgacaag ctgtatcact gccttcgttt      480

atattttttt aactgtgata atccccacag gcacattaac tgttgcactt ttgaatgtcc      540

a                                                                      541


<210>  4597
<211>  462
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (81)..(81)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (173)..(173)
<223>  n is a, c, g, or t

<400>  4597
gagaaccact gaggtccaat gatgagactt ggaggtctgg atccagtctc tctttgtttt       60

aatgtgactt aggtgctgtc nacattagca agataatgga aatcacgacg ccagtgggtg      120

cttacctccc tgctaggcat gcaggggctg gcggttggca ggggaaggag gcncagtgag      180

ccgggtccct taggggaggg agagtttgtc ctctttgccc cacagtctac ccttcagggc      240

cttgtggcag tgccagtgtt cggggggtgt ctgggccact gagtacccac tcggtcgtgg      300

ttgtgctggc ctcttgggtg agtgaacctg tgaagcccag gaggtggtgt tggctgcagg      360

gtacacaaat actgagtggt ggtcttttgt tacaggctta gcaacaaagc tgtgccctgg      420

gcatgggggg ctgtagtgta gctacagttg tgcgtttgtg aa                         462


<210>  4598
<211>  299
<212>  DNA
<213>  homo sapiens

<400>  4598
gaaagggcac ttggaaccca ccgagctgct gatgaaccgg gcttacttgc agagcattac       60

ccctcagggg tactctgact cggaggagag ggagagtatg ccgagggatg gcgagagcga      120

gaaggagcac gagaaagaag gcgaggatgg ctacgggaag ctgggcagac agggtggcga      180

cgaggagttc gaggaggaag aggaagaaag tgaaaataaa agtatggata cggatcccga      240

aacgatacga gatgaagaag agactggaga tcactccatg gacgatagtt cggaggatg       299


<210>  4599
<211>  556
<212>  DNA
<213>  homo sapiens

<400>  4599
ctctggagac catcaaggca ttcaaagaca agcagatcca cccgggcttt ggcagcctgc       60

cccagccgcc gctcaccctc aagcccatcc ggccccgcaa gtaccccaac cggcctagca      120

agacaccgct ccacgaacgg ccccacgcgt gcccggccga gggctgcgac cgccgtttca      180

gccgttcgga cgagctgacc cggcacctgc gcatccacac gggccacaag cccttccagt      240

gccggatctg catgcggagc ttcagccgca gcgaccacct caccactcac atccgcactc      300

atacgggcga gaagcccttt gcctgcgagt tctgcgggcg caagtttgcg cgcagcgacg      360

agcgcaagcg ccacgccaag atccacctca agcaaaagga gaagaaggcg gagaagggcg      420

gtgcaccctc tgcatcctcg gcgccccccg tgtcgctggc ccccgtggtc accacctgcg      480

cctgaggatc gggcccccag atccccactt ttcccctcca gtgcctcccg gctgctagcc      540

tgaaagcagc gggaaa                                                      556


<210>  4600
<211>  513
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (31)..(31)
<223>  n is a, c, g, or t

<400>  4600
gagagccacg ttccccaaga aaatgaagaa naagaggaaa aagagcccag tcaggcagct       60

gccatccacc ccgacaactg tgaagaaagt gaagtcagcg agagggaggc ccaacctccc      120

tgtcccgagg cccatgggga ggagttgggg ggatttccag aggtaggcag cccagcctct      180

ccgccagcca gtggagggct caccgaggag cccctggggc ccatggaggg ggagctccca      240

ggagaggcct gcacactcac tgcccatgaa ggaagagggg gcaagtgtac cgaggaaggg      300

gatgcctcac agcaagaggg ctgcacctta ggttctgacc ccatctgcct cagtgagagc      360

caggtttctg aggaacaaga agagatggga gggcaaagca gcgcggccca ggccacggcc      420

agtgtgaatg cagaggagat caaggtagcc cgtattcatg agtgtcagtg ggtggtggag      480

gatgctccaa acccggatgt cctgctgtca cac                                   513


<210>  4601
<211>  536
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (109)..(109)
<223>  n is a, c, g, or t

<400>  4601
agacctactc ttacctggca gtttacttaa cttactgttt tgagtcctaa acttagagtt       60

gttaatgctt atatataatc taaccaaaga gttacccagt agggttttna gtttttgaac      120

ttttattttc ttgttgatta taaatcctga ttttggaatc tattgcgcaa aagaagtttc      180

attttggtta cttagaccta agatcactta ttaaaaatcc ttattttctc caagcccagc      240

aaacgttgac ttctgggcaa acctgaaaac ctgaaaatgc cactttcatg cagtttgttt      300

gaagttaagt ggaatccttt caaatgacga gctgcagaga actcagcacc aagggctgcc      360

tatctgtaga tagctgtaaa atggaatatt tttaaatgaa ggcaaataag tacttaaaag      420

tgagctgagc aataaaatgg tccaataata ggtaaatgca acagaaacag aaggagacct      480

ggttgcctta tgcctttact cttacatgga ataaattccc aatgcatatc ctatgt          536


<210>  4602
<211>  478
<212>  DNA
<213>  homo sapiens

<400>  4602
tattttcaag tagtataccc ctgtggtttt acaatgtttc atcatttttt tgcattaata       60

acaactgggt ttaatttaat gagtattttt ttctaaatga tagtgttaag gttttaattc      120

tttccaactg cccaaggaat taattactat tatatctcat tacagaaatc tgaggttttg      180

attcatttca gagcttgcat ctcatgattc taatcacttc tgtctatagt gtacttgctc      240

tatttaagaa ggcatatcta catttccaaa ctcattctaa cattctatat attcgtgttt      300

gaaaaccatg tcatttattt ctacatcatg tatttaaaaa gaaatatttc tctactacta      360

tgctcatgac aaaatgaaac aaagcatatt gtgagcaata ctgaacatca ataataccct      420

tagtttatat acttattatt ttatctttaa gcatgctact tttacttggc caatattt        478


<210>  4603
<211>  175
<212>  DNA
<213>  homo sapiens

<400>  4603
ggccaccata tgtgtgtgcc taggtcctcc ttctgcacga tccaatagga gacaccagtt       60

ctgactgaac catgccccca cctaagtcac aaaatgaggg aagtggggag ttagatttca      120

gagtccaggc cctaggttgg gacccactcc aaataatctc ctcggtgtgg gtggt           175


<210>  4604
<211>  282
<212>  DNA
<213>  homo sapiens

<400>  4604
tagtaggtgt tggaccagca gaatttgatg caatggtcga attggatgga gatgatgtaa       60

gagtctcctc tagaggaaaa tatgctgaaa gagacattgt gcagtttgtg ccattcaggg      120

attatattga cagaagtgga aaccacatac tgagcatggc tagattggct aaagatgtcc      180

tagctgagat ccctgagcag tttctctcct atatgagagc ccgaggaatc aagccatcac      240

ctgcgcctcc cccatacacc ccacctacac atgtgttaca ga                         282


<210>  4605
<211>  523
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (33)..(33)
<223>  n is a, c, g, or t

<400>  4605
accggcgtgt gaaccccgag agtgcccgcg ccntgctccc gggggacccg caaggacccg       60

ggaccgccgc tcctcgcgcg ctcggactcc cgccccgctg cgaaccggtc ggtgcgcccc      120

tcgccgcgct cgccctggcc cgggagcgcc gggagcgggg ccgctttcct cgtccttgta      180

aatgtttatt ttttaactct tcccagtgcg aactctgctg tgagtgtgtg cggggaggcg      240

cgcccgcgct gagtcggcgg cgggtagcca ctccatgccc ttgtccgatg gtttgcaact      300

ccgattttgc acaccgctcc accgtgcccc ccagcgcaca cccattcaca ctcacgccaa      360

cactctcgct gaacactttt ataattgtta ggcgtggccg ttgggacttt gggcgcagcg      420

cggctgctac tgcgtctgga ggattgatat ttatttttgc attgcgatgg ctgaaggcat      480

ttatttaacg atctttttac ctggatatgt ctgtgaggct cct                        523


<210>  4606
<211>  67
<212>  DNA
<213>  homo sapiens

<400>  4606
caaggaaatg gtagaactag tgatctcacc cagcctcact gtaaacagcg attgtctgga       60

taaactg                                                                 67


<210>  4607
<211>  457
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (45)..(45)
<223>  n is a, c, g, or t

<400>  4607
ttttggaagc atgctcatct cctcacactg ctgccctatg gaagntccct ctgcttaagc       60

ttaaacagta gtgcacaaaa tatgctgctt acgtgccccc agcccactgc ctccaagtca      120

ggcagacctt ggtgaatctg gaagcaagag gacctgagcc agatgcacac catctctgat      180

ggcctcccaa accaatgtgc ctgtttctct tcctttggtg ggaagaatga gagttatcca      240

gaacaattag gatctgtcat gaccagattg ggagagccag cacctaacat atgtgggata      300

ggactgaatt attaagcatg acattgtctg atgacccaaa ctgcccatgt catttgtttc      360

cagaaacgag gaccaataat tctctcacac tggcatttgt gctggtagta caagtccttt      420

aatatgtcca ggaagggagc cattgcccag tggtcca                               457


<210>  4608
<211>  323
<212>  DNA
<213>  homo sapiens

<400>  4608
agctgagcaa gcaattctgg tggaaagtca aacctgtcag tgctccacac cagggctgtg       60

gtcctcccag acatgcatag gaatggccac aggtttacac tgccttccca gcaattataa      120

gcacaccaga ttcagggaga ctgaccacca agggatagtg taaaaggaca ttttctcagt      180

tgggtccatc agcagttttt cttcctgcat ttattgttga aaactattgt ttcatttctt      240

cttttatagg ccttattact gcttaatcca aatgtgtacc attggtgaga cacatacaat      300

gctctgaata cactacgaat ttg                                              323


<210>  4609
<211>  177
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (104)..(104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (124)..(124)
<223>  n is a, c, g, or t

<400>  4609
gagctcttca catctctgac taattatcat cattaccatg gagcccaaca gtcccaaaaa       60

gatacagttt gccgtgcctg tattccagag tcagattgca cctngaagca gcagagcaga      120

tcanggaaaa gaagacctac accagcatca cttgtgattc tcaatgagca taacccc         177


<210>  4610
<211>  66
<212>  DNA
<213>  homo sapiens

<400>  4610
atatttttgt ttacctcgct agcttcagaa ttttgccaac ctctgaattt gcacattttg       60

tataat                                                                  66


<210>  4611
<211>  232
<212>  DNA
<213>  homo sapiens

<400>  4611
accaatagga agatctcagt gcagaggctc gcgagctata gaagaatcac cagcagcaag       60

tgtcccaaag aagctgtgat cttcaagacc attgtggcca aggagatctg tgctgacccc      120

aagcagaagt gggttcagga ttccatggac cacctggaca agcaaaccca aactccgaag      180

acttgaacac tcactccaca acccaagaat ctgcagctaa cttattttcc cc              232


<210>  4612
<211>  589
<212>  DNA
<213>  homo sapiens

<400>  4612
tagtgggtcc cctgtgtaac tcctatgatg ctgctggttt gctaccaggt cagtggttag       60

aagcagaaga ggataatgat actgaaagtg gtgatgatga agacggtgaa gaattagata      120

cagaagatga agaaatggaa aacaatctaa atccaaaacc accaagaagg aaaagcagac      180

ggcgaatatt ttgtcagcta atgcaccacc tcactgaaaa ccacaagata tggaaggaaa      240

tcgtagagga agaagaaaaa tgtaaagctg atgggaataa actgcaggtg gagaattcct      300

ccttacctca agcagatgag attcaggtaa ttgaagaggc agatgaagag gaatagcgac      360

agtttgagta aaagaaaagt catattgaag aagcccagag ggttgtgccc aggggcagaa      420

atcattgcct agtgttcacc ggctgactct caactgacca ttcccatgtg gacaggcctt      480

aatactgtga gaggatcctt gctctgctgg cagtttccca ctcctatgca ctttcacagg      540

aactagaaaa ctattcttaa accaaaaata ccatccgtgt tgacccatg                  589


<210>  4613
<211>  367
<212>  DNA
<213>  homo sapiens

<400>  4613
ggttttatcc aatgtctcaa gcaagcaatg tctgggaata tcatagagta acaagtgctg       60

gtcagccaaa gaaacattca ctgctggtga accaatacca taagcatgta ttatctaagc      120

acttgatcaa gaaatataca tgttgtacaa gctctcaatt ttgttcattt attatcaaat      180

ttttaaaata caagtttggt atgtgatttg gaaaagatgc cttctggatc ttaagccagt      240

tgtcagtgga ggtcctcagg gctgcaaatg tcaagacata accctgttcc tcaccatcat      300

gataccagat acaggtgaat acataggaac tatctgcctg tgtcctcaat ctcccttcaa      360

acaagat                                                                367


<210>  4614
<211>  166
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (130)..(130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (139)..(139)
<223>  n is a, c, g, or t

<400>  4614
tcgaagaaga ggctgagtgc gtccctgata actgcgtcta agaccagagc cccgcagccc       60

ctggggcccc ccggagccat ggggtgtcgg gggctcctgt gcaggctcat gctgcaggcg      120

gccgagggcn acagggggnt ttcgcgctgc tcctgaccgc ggtgag                     166


<210>  4615
<211>  313
<212>  DNA
<213>  homo sapiens

<400>  4615
acatttccac tatggtcggt ttcaggaatt tcaaaagaaa tctgacgtca atgcaattat       60

ccattattta aaagctataa aaatagaaca ggcatcatta acaagggata aaagtatcaa      120

ttctttgaag aaattggttt taaggaaact tcggagaaag gcattagatc tggaaagctt      180

gagcctcctt gggttcgtct acaaattgga aggaaatatg aatgaagccc tggagtacta      240

tgagcgggcc ctgagactgg ctgctgactt tgagaactct gtgagacaag gtccttaggc      300

acccagatat cag                                                         313


<210>  4616
<211>  400
<212>  DNA
<213>  homo sapiens

<400>  4616
cctgttccac atccggaggg tgatgaagac gggcggcgag aacacggaca agctggagaa       60

gctcatggtg cgtatcgggc tcttctctgt gctgtacacc gtgccggcca cctgtgtgat      120

cgcctgctac ttttacgaac gcctcaacat ggattactgg aagatcctgg cggcgcagca      180

caagtgcaaa atgaacaacc agactaaaac gctggactgc ctgatggccg cctccatccc      240

cgccgtggag atcttcatgg tgaagatctt tatgctgctg gtggtgggga tcaccagcgg      300

gatgtggatt tggacctcca agactctgca gtcctggcag caggtgtgca gccgtaggtt      360

aaagaagaag agccggagaa aaccggccag cgtgatcacc                            400


<210>  4617
<211>  529
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (225)..(225)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (241)..(241)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (251)..(251)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (287)..(287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (298)..(298)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (305)..(305)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (309)..(309)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (351)..(351)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (364)..(364)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (375)..(375)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (379)..(380)
<223>  n is a, c, g, or t

<400>  4617
atctatatat aacgccacac tgtcttctgt ttagtgtatg gggaaagacc aatccaactg       60

tccatctgtg gctgggacag cccagggggt gtgcccacgg ctgacccagg ggtgtgcaca      120

cggctgagct gggagtcccg ctggtctccc tgaggactga gggtgaactt cgctctttgc      180

cttaaacctc tttatttcat tgcagtaata gttttacgtt gtacnataat agtgtaaacc      240

nttttaaaaa nggaaagtat aaaaacaaaa gttgtaattt aaaagtnctg aataaccnat      300

ctgcntgcnt taggaaactc aatgaaatga catgcctttt tagcaggaag ncaaagttgg      360

tttnctgttt tttgntttnn tttgttgttt tagtttataa aacatgtgca ttttacagtt      420

ccagtatcaa atatttataa tcttatgaga aatgaatgaa tgtttctatt tacaactgtg      480

cttatcaaaa ttgtgaacac ccccaccccc gcatttttgt gtgttgaaa                  529


<210>  4618
<211>  129
<212>  DNA
<213>  homo sapiens

<400>  4618
aggtcactcc gagaagcccc taagttattg accggtttca gtgttgtata tataaatatg       60

caagatgtgc cttacaatga agttgttgga agctatttcc aatcacattg gtactgtttg      120

gtatttgca                                                              129


<210>  4619
<211>  61
<212>  DNA
<213>  homo sapiens

<400>  4619
aatgaagaac tctttttaac ctcagaccaa cttggctaca gctatgccat cgatctgcca       60

g                                                                       61


<210>  4620
<211>  230
<212>  DNA
<213>  homo sapiens

<400>  4620
tcatcctgtt tcaaccccag aagaatgttg tcacacacag actgcacctc aacaggttca       60

gtgtcagtgg aactgggacc acatactctc agtcctctgc aagcacgtat gtgccaacgg      120

tgtgcaatgg gcgggaagtc ctcgactcca ccacctcatc tctgtgattg tgaattgcag      180

ttcagttctt gtgtttttag actgttagac aaaagtgctc acgtgcagct                 230


<210>  4621
<211>  520
<212>  DNA
<213>  homo sapiens

<400>  4621
aaacctgtgc ttgatctgac atttgtatac ataaaagttt acatgaattt tacaacaaac       60

tagtgcatga ttcaccaagc agtactacag aacaaaggca aattaaaagc agctttgtga      120

acttttatgt gtgcaaagga tcaagttcac atgttccaac tttcaggttt gataataata      180

gtagtaacca cctacaatag ctttcaattt caattaactc ccttggctat aagcatctaa      240

actcatcttc tttcaatata attgatgcta tctcctaatt acttggtggc taataaatgt      300

tacattcttt gttacttaaa tgcattatat aaactcctat gtatacataa ggtattaatg      360

atatagttat tgagaattta tattaacttt tttttcaaga acccttggat ttatgtgagg      420

tcaaaaccaa actcttattc tcagtggaaa actccagttg taatgcatat ttttaaagac      480

aatttggatc taaatatgta tttcataatt ctcccataat                            520


<210>  4622
<211>  546
<212>  DNA
<213>  homo sapiens

<400>  4622
agaacatagt ttagcaagtt tatatttgat atcctgagcc atatttcttt aatttctctt       60

tatatgtggt atttgtgtat gttagtatat ttgaatttta tgttttttta acataattaa      120

gcgtgcatgt ttgtttttca ttaacggtta aaagatattt gatgaattgt gtgtttgatt      180

aacctattaa ctgaaaaaaa ctcaacagta gaaatggaat tataatcaca tcataaatat      240

aagcagtttt taatgatcaa tttttatatc tgtacagttt ttttggattg ttttagttcc      300

ttagaaaaat tagctaaatg acagaaacat ggatattgaa atatgaaata gtacaatata      360

aagatagata gaaaagtatg ctgagttgac atgttgaaaa acacagtctc ttgaagatat      420

actggaatac attatttttg aatattttga atattttttg aatattttta aataaagtct      480

taaaagcata aataggtaac tacttttaaa aaaaaagtca tgagaaatca cactcaagca      540

ttatca                                                                 546


<210>  4623
<211>  506
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (174)..(176)
<223>  n is a, c, g, or t

<400>  4623
tcaatggaga caaggcctcg gtccgcagca gccccacgct cccagagaga gacctcgtcc       60

ccaggccaga ttcgccggca cagcagttaa agtcgccctt ccagccggta cgcgacaact      120

ctctggcccc gcaggaggga acgccgcgga tcctagcagc cctcccgtcc gccnnntgat      180

taagggtctt cttttacttt tgcggggggg aggggggagg agttggggag ggagggaatg      240

tgggaggaat taagacaaat atttcagact ggtgtaaagg acaaatatga caacgacgtc      300

aaggactcgc atccgtcgct ttctgcagaa aggggcttct tcggtcccga gctcgcgtcc      360

aggtggccag gcctctgccg gcggctccag tggctgcgat tatcgggttc ggtaaatgcc      420

cccacgtgct tgtgtctctt tccccccttt tctgtatata gagtggtttc agattgtaaa      480

tagcgcgtca gcgaacttgt ctaaat                                           506


<210>  4624
<211>  558
<212>  DNA
<213>  homo sapiens

<400>  4624
aagaacatca ctgggcgagc ggtaaatcct aaagaaggtg ataaatgtca gtagtttctt       60

attaaatatt ctaattttag gttcccaaac cttcaggaaa tatatcttaa tgcagacaaa      120

caaacataaa acttctttag tacttacatc aggaaatttg gggcagattt tagagggggg      180

aaattatagg aggaaagaag ttcacatcag aacagacaat cacagcaatg ctctattcct      240

tagaaattag tgccacaaat aagttacatc tacaaacagg tggtaaaaat tctttctggc      300

ccagttaatt tgcacagaac ttttctcagt ttggtatttt ttactgcttg gagatccaga      360

agagaattag aaacaacata gcaaattaaa ataggtttgt caataataga gctcagacac      420

ctgtgtgctg tagattcaca tacaggccgt gaacctaagt ggggaaaatc ctacctatcc      480

accttctggc tagattacct agcttagtga aaagatagcc aaataattgg catgtgaatt      540

atttcctgct tattcata                                                    558


<210>  4625
<211>  551
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (36)..(36)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (42)..(42)
<223>  n is a, c, g, or t

<400>  4625
gaaagtctat gcttaggcca gtcagtacac ccaatnttta anaaaataac atattcttgc       60

tttcacaaat atagttgaac aagatttccc taaaaattcc accaggatta atctctaaaa      120

ttctagtctc tgatttgcaa atgcacattt gtcactgaat aatggaatta tgtataacaa      180

gccaaacatt cttattttag acaaccatag aactgtccca caaaatattt ctaagcttat      240

ttctaactat taggaggaat gtgcttttcc atctaaaata ctcaccaaaa tatagttaat      300

tgtggcttta tgaagttaac agtctcatta cagatttagt ttaccaatca acagcatgtc      360

tactgcttgg atccatacaa aactatcggt tcaagttgat gtgacaaggg aagggagcac      420

cagatgacac ataaatctgt ctgattctat gcctgtattt ccaacaaact tactgtcaga      480

gaatatgacc taaatccatt ttctaaactg ttttcatgtg ttgcaaatta ttctagtcaa      540

ctgctgtttt a                                                           551


<210>  4626
<211>  480
<212>  DNA
<213>  homo sapiens

<400>  4626
ctaaatggtt tagctccctc ttttttctct aaaaacaatc agctaataaa aaaaaaattt       60

gagggcctaa attatttcaa tggttgtttg aaatattcag ttcagtttgt acctgttagc      120

agtctttcag tttgggggag aattaaatac tgtgctaagc tggtgcttgg atacatatta      180

cagcatcttg tgttttattt gacaaacaga attttggtgc cataatattt tgagaattag      240

agaagattgt gatgcatata tataaacact atttttaaaa aatatctaaa tatgtctcac      300

atatttatat aatcctcaaa tatactgtac cattttagat attttttaaa cagattaatt      360

tggagaagtt ttattcatta cctaattctg tggcaaaaat ggtgcctctg atgttgtgat      420

atagtattgt cagtgtgtac atatataaaa cctgtgtaaa cctctgtcct tatgaaccat      480


<210>  4627
<211>  451
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (264)..(265)
<223>  n is a, c, g, or t

<400>  4627
ttcagctctc tagtgagatg cccgtgtctg tgcgtgtgcg tgtgtgtttc atacagctag       60

cattagatgg gtgatgtttc ttacttatca tccctaacta ttgcaacttg accttaaaaa      120

gacaaaaccc cacaaaactc ttcctgccac gggcttgcag attgaagcac tttcgatgtt      180

gggcgctggc gtttgtgttc tgggcaccac cgtgaccctg cccagatggc tataatatta      240

ttttatacac aaaccttttt tttnnataaa tgttataatt ttgtgtctgt ctttataaac      300

tattataagt actatttttg ttataattca aaatagatat ttagtataaa gtttttgctg      360

ttaaatattt gttatttagt aaaatatgaa ttttgctcta ttgtaaacat ggttcaaaat      420

attaatatgt ttttatcaca gtcgttttaa t                                     451


<210>  4628
<211>  190
<212>  DNA
<213>  homo sapiens

<400>  4628
gatgcagcta gcctgaaagg actgaataat ttggctaagt tgggattgag tttcaacagc       60

atctctgctg ttgacaatgg ctctctggcc aacacgcctc atctgaggga gcttcacttg      120

gacaacaaca agcttaccag agtacctggt gggctggcag agcataagta catccaggtt      180

gtctaccttc                                                             190


<210>  4629
<211>  443
<212>  DNA
<213>  homo sapiens

<400>  4629
acataaagtc ctgctggtga cagcttctaa caggttcaag acactaatga ccaataaatc       60

agaacaggat ggggacagca gcaagaccat cgagatcagc gacatgaagt accacatttt      120

tcagatgatg atgcagtatc tgtactacgg aggaacagaa tccatggaga tccccaccac      180

tgacatcctg gagctgctgt cagctgccag cctgttccag ctggatgccc tgcagaggca      240

ctgcgagatc ctgtgctccc agaccctcag catggagagt gccgtgaaca cctacaaata      300

tgccaagatc cacaatgccc cagaactggc cctgttctgt gagggcttct tcctcaagca      360

catgaaggcc ctactggagc aggatgcctt ccggcagctc atctacggcc gcagcagcaa      420

agtgcagggc ctggatccac tgc                                              443


<210>  4630
<211>  293
<212>  DNA
<213>  homo sapiens

<400>  4630
tcttccgcgt gtgcctcaag cactaccagg ccagcgtgtc ccccgagccg ccctgcacct       60

acggcagcgc cgtcaccccc gtgctgggcg tcgactcctt cagtctgccc gacggcgggg      120

gcgccgactc cgcgttcagc aaccccatcc gcttcccctt cggcttcacc tggccgggca      180

ccttctctct gattattgaa gctctccaca cagattctcc tgatgacctc gcaacagaaa      240

acccagaaag actcatcagc cgcctggcca cccagaggca cctgacggtg ggc             293


<210>  4631
<211>  447
<212>  DNA
<213>  homo sapiens

<400>  4631
aaattcctag gatgcagtgt ctcattgtcc ccaactttac tactgctgcc gtcaatggtg       60

ctactatata tgatcaagat aacatgctga ctagtaacca tgaagattca gatgtacctc      120

agcaatgcgc cagagcaaag tctctattat ttttctacta aagaaataag gaagtgaatt      180

tactttttgg gtccagaatg actttctcca agaattataa gatgaaaatt atatattttg      240

cccagttact aaaatggtac attaaaaatt caattaagag aagagtcaca ttgagtaaaa      300

taaaagactg cagtttgtgg gaagaattat ttttcacggt gctactaatc ctgctgtatc      360

ccgggttttt aatataaagg tgttaagctt attttgcttt gtaagtaaag aatgtgtata      420

ttgtgaacag ccttttagct caaaatg                                          447


<210>  4632
<211>  135
<212>  DNA
<213>  homo sapiens

<400>  4632
gtaaagatct aatttccagg cgctttcagg gcactgtaat ttcaacaata ctggaatcat       60

tttggcgctg cttctcattc attttaaggc ttctctgaat tgtgctcatt ccaaattaac      120

ccatgtatag aatct                                                       135


<210>  4633
<211>  479
<212>  DNA
<213>  homo sapiens

<400>  4633
gattcttgcg atgtatgtgc cttattttat gttaatcttg tcaatgagag ggaccagttg       60

gtgttgccca atcagcactc caaggctgtg tgtgcaccag ccagagagcg cacggtggta      120

gcagagtcga ggctgtcttg tatcctggtt tcatgtgttg ttttgaactg ataggaggat      180

gttctcttct gacaagttac ccttgtgtat cctgcagaca tgtaaaataa aatacaagtt      240

catttttttc acctttttta gattttttta aaaaataaaa tgtgtaatcc tttttttaaa      300

agaaacacat gtaaatacat ttaagtattg taggcatagc gttcagatgt gactggccca      360

ggcgttcctc ggacaagcct gcattccccg tgatcacgcc cacctcaagc ccaggggctg      420

cagcccagcc acagatgaac tctacctttg ctttcagaac cacttagtcc ttttgtaac       479


<210>  4634
<211>  540
<212>  DNA
<213>  homo sapiens

<400>  4634
ttgcagccga cacggtctcg gatcaggctc ccaggagcct gcccagcccc ctggtacttt       60

gagctcccac ttctgccaga tgtcctaatg gtgatgcagt cttagatcat agttttattt      120

atatttattg actcttgagt tgtttttgta tattggtttt atgatgacgt acaagtagtt      180

ctgtatttga aagtgccttt gcagctcaga accacagcaa cgatcacaaa tgactttatt      240

atttattttt tttaattgta tttttgttgt tgggggaggg gagactttga tgtcagcagt      300

tgctggtaaa atgaagaatt taaagaaaaa aatgtccaaa agtagaactt tgtatagtta      360

tgtaaataat tcttttttat taatcactgt gtatatttga tttattaact taataatcaa      420

gagccttaaa acatcattcc tttttattta tatgtatgtg tttagaattg aaggtttttg      480

atagcattgt aagcgtatgg ctttattttt ttgaactctt ctcattactt gttgcctata      540


<210>  4635
<211>  138
<212>  DNA
<213>  homo sapiens

<400>  4635
ttttgttctt tacatcaaga aattttatgt ttaaatatgc ggagaatgta tattgcctct       60

gctcctatca gggttgctaa accctggtac atcgtatata aaatgtatta aaactggggt      120

ttgttaccag ttgctgta                                                    138


<210>  4636
<211>  514
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (463)..(463)
<223>  n is a, c, g, or t

<400>  4636
gcgttggacc ttcatgaaca gtggcctggc tggcgtggca gggccaaggc ccacccactg       60

ccatccccct tctgtgtgtc cctctccccc agttatgagg cccagggcct gagctctctt      120

ccccagcatt gcccccaccc ggaaacccca cctttggaga gttaattgtc tgtgtgaggt      180

gcttaaccta tcagccctga gaacacaaag caataatctt tgttactgag atgcgcggct      240

gttcgtgttt tgggtttttt ttttttttaa tgtttcctaa taaaagagaa gctgcatttt      300

attggttttt atttttaatt ttctacacgt ttgagctgag tcctgagaca cttagcttcc      360

ctctccctca ttcccggacc cttccacccc actgggccca accatgggct caggaccctg      420

gaattccgtt ttctgatttg ctttgggatt tttttttttt ttnaagatgt tacatggtgt      480

ttcgaagcca gcaagttacc atcctccggt gtct                                  514


<210>  4637
<211>  425
<212>  DNA
<213>  homo sapiens

<400>  4637
caagaccgaa aagctggagc ggctcatggt gcgcatcggc gtcttctccg tgctctacac       60

agtgcccgcc accatcgtca tcgcttgcta cttctacgag caggccttcc gcgagcactg      120

ggagcgctcg tgggtgagcc agcactgcaa gagcctggcc atcccgtgcc cggcgcacta      180

cacgccgcgc atgtcgcccg acttcacggt ctacatgatc aaatacctca tgacgctcat      240

cgtgggcatc acgtcgggct tctggatctg gtcgggcaag acgctgcact cgtggaggaa      300

gttctacact cgcctcacca acagccgaca cggtgagacc accgtgtgag ggacgccccc      360

aggccggaac cgcgcggcgc tttcctccgc ccggggtggg gcccctacag actccgtatt      420

ttatt                                                                  425


<210>  4638
<211>  471
<212>  DNA
<213>  homo sapiens

<400>  4638
tccatactgt tttaggcagc accgtttatg tgacagagtc cgtgtttctc aaatgcatgg       60

tgttcctcag gtggagagtg ggcagaagtt tttgcaacac ttttttttta agttattggg      120

tgcaaaatcc caaaccagga tatgtgtatg tctgtgtgtt tatgtttttt atttgaccct      180

cccctctttc aacctacccc cttttatatc taatgtagaa aaagcgaaat tgaatctgga      240

aagcaaactg ttgtatatag ttgcggtaac aatcatgaag agagagccgg gctgtcccct      300

cagtaattca ttttaaataa caaattattt aaaaataaaa ttcatgccag agccagctga      360

agaggccttc cttcatcacc actgaggcca cccccaatct gggccctctg tccatctggc      420

atgtctcctc ccagcaagat tcatctgttc aatgccattt gcgtttcaat a               471


<210>  4639
<211>  306
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (58)..(58)
<223>  n is a, c, g, or t

<400>  4639
tcattattta taagtggcct ctcttagctc agttactcaa ttcatacgta gatatttntt       60

taaaataatt ttatatctgt gtaccacccc atatatttca tattactgtt tcacatgtac      120

agctttctac ttctttgtaa gaacaccaac caaccaaggt ttaagtgatt aataggcttg      180

agcaccgggt ggcagatgtt ctatgcagtg tggttcaagt ttctttgacc gcacttatat      240

gcattgctaa tatggaattt aagataccat acacagtctc tcatggacct atctctattg      300

tagaat                                                                 306


<210>  4640
<211>  315
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (213)..(213)
<223>  n is a, c, g, or t

<400>  4640
gcaaccccca aaatggattc tgcgaggatg acaatgtttg caggtgccag cctggctggc       60

agggtcccct ttgtgaccag tgcgtgacct ctcccggctg ccttcacgga ctctgtggag      120

aacccgggca gtgcatttgc accgacggct gggacgggga gctctgtgat agagatgttc      180

gggcctgctc ctcggccccc tgtgccaaca acnggacctg cgtgagcctg gacgatggcc      240

tctatgaatg ctcctgtgcc cccgggtact cgggaaagga ctgccagaaa aaggacgggc      300

cctgtgtgat caacg                                                       315


<210>  4641
<211>  513
<212>  DNA
<213>  homo sapiens

<400>  4641
agatcactgt tcaaaccctg tcatgcttta aaactgatgc gagatgattt tgttttttgc       60

ataatcaata cttaagggtg caatcaactg ttagtaattg tgcagtaaag taaagccctg      120

tggtgtatca actactagtt aagagtctca gttgatttct gtaatgtttg acctaataat      180

agcccgtttc gtctctgacc caacagagga agcacagatc aaatcacctt ggagtggtca      240

ccagggggac agggagcccc ccaccaatgt atcaatgggt gatttatgat gccttctgcc      300

ctttggcgag tgaatgggtt tcccataggg gaagttggcc tccctccgtg agctttggaa      360

atgttttcta atagacacag ggaggccagt tctgtttcag agcaattatc ttcccaaatt      420

ctctgttctg gtgttggaac tgtgtgccct ggtttctgtt ttcctttcta ctgctgtaat      480

tctctgtctc atcatccttc tcttttgttt cca                                   513


<210>  4642
<211>  503
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (90)..(90)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (104)..(104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (129)..(129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (182)..(182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (191)..(191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (202)..(202)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (220)..(220)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (222)..(222)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (224)..(224)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (232)..(232)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (234)..(234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (242)..(242)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (246)..(247)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (251)..(251)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (280)..(280)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (286)..(286)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (289)..(289)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (304)..(304)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (313)..(313)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (343)..(343)
<223>  n is a, c, g, or t

<400>  4642
aagatgctgc aatgtgagtt atcacttcat ttatcttaaa gaaagactaa actggttgtc       60

agttacatct gacagaaaaa aaaaaaaaan tcactgtgta accnggttaa gtggtaaaat      120

aatccaggnc gtcagtcaaa ggcattttgc tgactttaat attgattata tttttaacag      180

gnaatttaag naaaatatta cnggaattaa aaatatatan tntnttaaac angnaatttt      240

cnttgnnctc ngtctagctt aaactactac tcaagctgcn ttaagntcnt taagtattgt      300

ttgntaatca ccnaataaat aagtgcattt gtaattcatc agncattatt agcttttatt      360

aaaagaagat tacgttttac aatgtaacta taatctcttg aatttggtat cttattaatg      420

agttttaaag atgtaaaacc taaccttttt taaagctcca ttgtcttatg tttttagagg      480

cttttccgta aacatatatc tta                                              503


<210>  4643
<211>  217
<212>  DNA
<213>  homo sapiens

<400>  4643
ggaaatcacg ttgagaagtt ggtctgtcat ctcccattga gcaaagactg gcaggagata       60

ataaaaataa atatgggcac acatgtatta atatacagca cgcatttaca agtttatttt      120

ccagataaaa ttgtgctata agaacagctc taccaagaca gtctgcacca tttccaagtc      180

tcagttaatt tacagcaact gctgctttcg gagatgg                               217


<210>  4644
<211>  479
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (281)..(281)
<223>  n is a, c, g, or t

<400>  4644
gggacactgt caacctctat accagctctg gctgcctctg ccctccactt aatgttaatg       60

aggaatatat catcatgggc tatgaagatg aggaacgttc cagattactc ttggtggaag      120

gctctatagc tgagaagtgg aaggatcgac tcggtaaaaa agttaagcgc tgggatatga      180

agcttcgtca tcttggactc agtaaaagtg attctagcaa tagtgattcc actcagagtc      240

agaagtctgg caggaactcg aacccccggc aagcacgcaa nctaaatccc gaaatacaaa      300

aagtaacaca gtggacttcc tattaagact tacttgcatt gctggactag caaaggaaaa      360

ttgcactatt gcacatcata ttctattgtt tactataaaa atcatgtgat aactgattat      420

tacttctgtt tctcttttgg tttctgcttc tctcttctct caaccccttt gtaatggtt       479


<210>  4645
<211>  537
<212>  DNA
<213>  homo sapiens

<400>  4645
attgaggaag gctatcggtt accccctcca atggactgcc ccattgcgct ccaccagctg       60

atgctagact gctggcagaa ggagaggagc gacaggccta aatttgggca gattgtcaac      120

atgttggaca aactcatccg caaccccaac agcttgaaga ggacagggac ggagagctcc      180

agacctaaca ctgccttgtt ggatccaagc tcccctgaat tctctgctgt ggtatcagtg      240

ggcgattggc tccaggccat taaaatggac cggtataagg ataacttcac agctgctggt      300

tataccacac tagaggctgt ggtgcacgtg aaccaggagt aagtactcaa cgatgtaaca      360

cgaaagggga cctggcaaga attggtatca cagccatcac gcaccagaat aagattttga      420

gcagtgtcca ggcaatgcga acccaaatgc agcagatgca cggcagaatg gttcccgtct      480

gagccagtac tgaataaact caaaactctt gaaattagtt tacctcatcc atgcact         537


<210>  4646
<211>  212
<212>  DNA
<213>  homo sapiens

<400>  4646
catcctccac tatagataca acggactttg actaaaagca gtgaagggga tttgcttcct       60

tgttatgtaa agtttctcgg tgtgttctgt taatgtaaga cgatgaacag ttgtgtatag      120

tgttttaccc tcttcttttt cttggaactc ctcaacacgt atggagggat ttttcaggtt      180

tcagcatgaa catgggcttc ttgctgtctg tc                                    212


<210>  4647
<211>  358
<212>  DNA
<213>  homo sapiens

<400>  4647
tcctggttct caaagctcta gtttcttcta atttctggat catcgcaagt ctggccctct       60

ttgaacttta aaacataatg tctaattcca ccccaatttt cagcatttct tcaactaaat      120

cgataaagct gtctccatta tgagaaaggc cagaataata ctccgagtaa gcataagaaa      180

gctggtcatt ttacaacttc tcccgactct aggaagtaat atgatgccat ttgttgagca      240

tctacagtgt gccaagcaca tggttcatct ctgcaaactg ctgctacatt ctgtaaagca      300

agtattatcc gcattttagg gattaggaac agcttcctga tctcttgcca aaagtcac        358


<210>  4648
<211>  419
<212>  DNA
<213>  homo sapiens

<400>  4648
tagtcagaac acctcagaca ctcagaacgc ctcatttaat tctgtctagt agttcccagc       60

gtcctgtaat ttatcagtgg aacaaagcaa cacaattatt cactaaccaa actgacattc      120

ctaacatgga ggatgtgtac gcagtgaagc acttctcagt gaaaggggac gtgtacattt      180

gcttgacaag attcattggt gattccaaag tcatgaaatg gggaggctcc tcgttccagg      240

atattcagag gatgccatcg cgaggatcca tggtgttcca gcctcttcaa ataaataatt      300

accaatatgc aattcttgga agtgattact cctttactca agtgtataac tgggatgcag      360

agaaagccaa atttgtgaaa tttcaggaat taaatgttca ggcaccaaga tcattcaca       419


<210>  4649
<211>  191
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (44)..(44)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (48)..(48)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (107)..(107)
<223>  n is a, c, g, or t

<400>  4649
aaccgtgagg ctaatctagc tgctattatt gaacgtctgc aggnaaanag gagaggcatg       60

ctgcggaggt gcgcaggaac aaggaactcc aggttgaact gtctggnctg aagcaaggga      120

gggtctggca cgccccacca atagtaaatc cccctgccta tattataatg gatcatgcga      180

tatcaggatg g                                                           191


<210>  4650
<211>  250
<212>  DNA
<213>  homo sapiens

<400>  4650
gttagcagac ctaaagcaag cctgaattgg ctatgcagta cattgtattc tgtttggggg       60

aatttgtttt agccattttc tttaattacc agttttccag aacactctta gctatgttga      120

catgaggcag ttccttccag gtgattctgt ttccttaagt attatataaa ctgtgccaat      180

acagacaaag cataatcaat ataatctgaa ttattgttat ctttacctcc tgagtaataa      240

gcatggtgtc                                                             250


<210>  4651
<211>  514
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (40)..(40)
<223>  n is a, c, g, or t

<400>  4651
tggactgtct tccatcgaga ctcttctgac taacatacan ggggctgttg aaagttgcca       60

tagataatgc cagagctcaa gagaaacagg tccaactgga aaaaactgag ctgaagatgg      120

attttttaag ggaaagagaa ctaagggaaa cacttgagaa gcagttggct atggaacaaa      180

agaatagagc catagttcaa aagaggctaa agaaggagaa gaaggcaaag agaaaattgc      240

aggaagcact tgagtttgag acgaaacggc gtgaacaagc agaacagacg ctaaaacagg      300

cagcttcaac agatagtctc agggtcttaa atgactctct gaccccagag atagaggctg      360

accgcagtgg cggcagaaca gatgctgaaa ggacaataca agatggaaga ctgtatttga      420

aaactactgt catgtactga atctttcctg ttgaagaaat ccatgttata gaaaagaact      480

ttgcagtcag acattcgtca tgggaaagtt caga                                  514


<210>  4652
<211>  242
<212>  DNA
<213>  homo sapiens

<400>  4652
gatgtcaaag tgattgtgca agctaaatga agtaggctca gcgatagtgg tcctcttaca       60

gagaaacggg gagcaggacg acgggggggc tgggggtggc gggggagggt gcccacaaaa      120

agaatcagga cttgtactgg gaaaaaaacc cctaaattaa ttatatttct tggacattcc      180

ctttcctaac atcctgaggc ttaaaaccct gatgcaaact tctcctttca gtggttggag      240

aa                                                                     242


<210>  4653
<211>  449
<212>  DNA
<213>  homo sapiens

<400>  4653
tagccctgac tcagatctgc agtgaccctg acacttcctc acccagtgat gatcagctga       60

gccttacggc cctgtgtggc tatcactagc aaggccaagc cccgggtacc ctcagtgatg      120

gcagaggcca gattaacatt aggaatctca gtgcagaggt cctcagaggc tccagcatct      180

ctagtactac ctgaaggctc tcctaaccct ctccacacat tccatttaca gagtatgaga      240

gtcgtaggac ccttacaaga cccaacaagc cactcgatgc atttttctat cacattctca      300

atagttccag ctcaggatga aaggatagac acaaaattgt ttgaaaaaca ttttccaggc      360

ctggctccaa cctaaagcct gactgtcacg tgccttgctt gattttatat atattgtttc      420

aagaatagtc caatatagca ttccccaaa                                        449


<210>  4654
<211>  498
<212>  DNA
<213>  homo sapiens

<400>  4654
atgggtgccg gagattcgat gccactgtcc caaagccccc atcatcctag ttggaacgca       60

gtcggatctc agagaagatg tcaaagtcct cattgagttg gacaaatgca aagaaaagcc      120

agtgcctgaa gaggcggcta agctgtgcgc cgaggaaatc aaagccgcct cctacatcga      180

gtgttcagcc ttgactcaaa aaaacctcaa agaggtcttt gatgcagcca tcgtcgctgg      240

cattcaatac tcggacactc agcaacagcc aaagaagtct aaaagcagga ctccagataa      300

aatgaaaaac ctctccaagt cctggtggaa gaagtactgc tgtttcgtat gatgctggca      360

agacacccag aaaggctatt ttcagatgaa atcgatatta gaagctatat tagctgaaac      420

aactcctttt actgcgtaga acctatatcg agagtgtgtg tatatgtatt ataggaggag      480

ctctcaattt tatgtatt                                                    498


<210>  4655
<211>  382
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (79)..(80)
<223>  n is a, c, g, or t

<400>  4655
gcaaggccat tgcaacaggc atttaaaaat tattatcaaa catgcacatg cttgtacaca       60

cacacacaca cacacacann aacaggggca tttgtaaagg tgtccctgga atgtaagatt      120

tataatgttt aaggcaaggt gaaggcattg ccaagtgtgt gtcgctcata ggactagtgt      180

atattcactg aaagttaacc tgatgatttg ttattgtttg aaccatatgc tgatttgctt      240

ctggtttctg tttagtgtgt tctctctgat aaggggctga aagattctgc atcacacatc      300

ctctgagacc taccatgtcg cacactttgt taatgacaaa cttcactcta cactatacag      360

taccttgttg atatattcag ta                                               382


<210>  4656
<211>  108
<212>  DNA
<213>  homo sapiens

<400>  4656
acagtcagca ggcaactccg aaggacaacg agataagcac ctttcacaac ctcgggaacg       60

ttcattcccc gctgaagctt ctcaccagca tggccatctc ggtggtgt                   108


<210>  4657
<211>  457
<212>  DNA
<213>  homo sapiens

<400>  4657
aatgcgttct cctacagctg taagtgcttg gagggccatg gaggtgtcct ctgtgatgaa       60

gaggaggatc tgtttaaccc atgccaggcg atcaagtgca agcatgggaa gtgcaggctt      120

tcaggtctgg ggcagcccta ctgtgaatgc agcagtggat acacggggga cagctgtgat      180

cgagaaatct cttgtcgagg ggaaaggata agagattatt accaaaagca gcagggctat      240

gctgcttgcc aaacaaccaa gaaggtgtcc cgattagagt gcagaggtgg gtgtgcagga      300

gggcagtgct gtggaccgct gaggagcaag cggcggaaat actctttcga atgcactgac      360

ggctcctcct ttgtggacga ggttgagaaa gtggtgaagt gcggctgtac gaggtgtgtg      420

tcctaaacac actcccggca gctctgtctt tggaaaa                               457


<210>  4658
<211>  196
<212>  DNA
<213>  homo sapiens

<400>  4658
ggagttccag cgaggaaact gtgcccgggg agagaccgac tgccgctttg cacaccccgc       60

agacagcacc atgatcgaca caagtgacaa caccgtaacc gtttgtatgg attacataaa      120

ggggcgttgc atgagggaga aatgcaaata ttttcaccct cctgcacact tgcaggccaa      180

aatcaaagct gcgcag                                                      196


<210>  4659
<211>  327
<212>  DNA
<213>  homo sapiens

<400>  4659
agatctttat agttcgtgct tcataagcca attcttatta ttatttttgg gggactcttc       60

ttcaaagagc ttgccaatga agatttaaag acagagcagg agcttcttcc aggagttctg      120

agccttggtt gtggacaaaa caatcttaag ttgggcagct ttcctcaaca caaaaaaaag      180

ttattaatgg tcattgaacc ataactagga ctttatcaga aactcaaagc ttgggggata      240

aaaaggagca agagaatact gtaacaaact tcgtacagag ttcggtctat taattgtttc      300

atgttagata ttctatgtgt ttacctc                                          327


<210>  4660
<211>  457
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (354)..(354)
<223>  n is a, c, g, or t

<400>  4660
aactggtaca tcaatttctc tccaactccc tttgagcagg ggatctggaa gaagcactat       60

attcaaatgg tgaaagaact tcatattacc aagcctaaga cacccccaaa ggatggattt      120

gtaatcgctg acgttcaact agttacaagc aattctccag aggaaaaaca gtccccttta      180

tcagcttttc ggtcctcttc ctctttaaga aagaagaata actcagggga gaaagcactt      240

ccaccctggc gatcttctga taagcaccca acagatatca ttcgttttaa ttacctagac      300

aaccgtgacc ccatggagac tgtccagcaa ggaagaagaa aaagaaacca aatnacccca      360

gacttcagcc gacagtcaca tgataagaaa aataaattgc aggacagaac taggctaaga      420

aaagcacaat caatgatgtc gaggagaaat cccttcc                               457


<210>  4661
<211>  290
<212>  DNA
<213>  homo sapiens

<400>  4661
ctcttacttg atagacttac taataaaatg tgaagactag accaattgtc atgcttgaca       60

caactgctgt ggctggttgg tgctttgttt atggtagtag tttttctgta acacagaata      120

taggataaga aataagaata aagtaccttg actttgttca cagcatgtag ggtgatgagc      180

actcacaatt gttgactaaa atgctgcttt taaaacatag gaaagtagaa tggttgagtg      240

caaatccata gcacaagata aattgagcta gttaaggcaa atcaggtaaa                 290


<210>  4662
<211>  260
<212>  DNA
<213>  homo sapiens

<400>  4662
acctggagta caagataaca cacacacaca cacacacaca cacacacaca cacacacaca       60

cacacgccac ctttgggagc tcagcagccc cgagaggatt tgatagcttc accgcttcac      120

ctggttttac aaatgcggag actgaggttt agggcagtta agcttcttgc ttagcatcat      180

gtaggtaaag aatggtggaa agatatttga acccgacctg ggcaattcca cctctgaggg      240

ctgtcctcag aatgaatctt                                                  260


<210>  4663
<211>  417
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (173)..(173)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (306)..(306)
<223>  n is a, c, g, or t

<400>  4663
ggtagtatac aagatgtgcc cctttgtcta aataaatgtt ggcttaattt gcagaataga       60

taaaacaatt gatgtttttg tgtgttcaag aatgcattaa attcttttaa tagtaaaaag      120

tcaaattacg accataatga gtattttaat cttgttcttg ttcagtattt tgngtagatt      180

tttattgtaa ttgtcctgag ttctacagta tgtgaacaat atcgtgtgaa gtgtgttttt      240

gcatttgtgc atttaaatta tttatgtaac tagggctgtg agtaacactt tttttttttt      300

tttttnggtt aaagaaaagc tatatttaaa tattcaaata attatatatt tccatgtaaa      360

actaatgtga agactaatgt attttttata ttgcagtgta aaagctaaac ttgtttt         417


<210>  4664
<211>  292
<212>  DNA
<213>  homo sapiens

<400>  4664
ggttgtggaa gcctatggta ttcttggcta ttgcagctgt ggctctgtat gtgttaccca       60

acatgcgaca gcaggagtca gagttctgcc tcatggagtg atggcagacc ttggccagcg      120

cgagggcaga tccccagtgg ccaccaccct cagctttggg caggacacac tgtgccagaa      180

ccctccccat atgttccatg tgtccccatc tcctcagcct cagtcaccca ggctgaaaag      240

gcttgtgggg agcggctgac ttccatctcc tgccttgtgt aagaacctga gt              292


<210>  4665
<211>  514
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (340)..(340)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (394)..(394)
<223>  n is a, c, g, or t

<400>  4665
aattccagct gaacaacgac tgctcctccc ccgagttcat tgtgaattgc acggtgaacg       60

ttcaagacat gtgtcagaaa gaagtgatgg agcaaagtgc cgggatcatg taccgcaagt      120

cctgtgcatc atcagcggcc tgtctcatcg cctctgccgg gtaccagtcc ttctgctccc      180

cagggaaact gaactcagtt tgcatcagct gctgcaacac ccctctttgt aacgggccaa      240

ggcccaagaa aaggggaagt tctgcctcgg ccctcaggcc agggctccgc accaccatcc      300

tgttcctcaa attagccctc ttctcggcac actgctgaan gctgaaggag atgccacccc      360

ctcctgcatt gttcttccag ccctcgcccc caanccccca cctccctgag tgagtttctt      420

ctgggtgtcc ttttattctg ggtagggagc gggagtccgt gttctctttt gttcctgtgc      480

aaataatgaa agagctcggt aaagcattct gaat                                  514


<210>  4666
<211>  580
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (126)..(126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (132)..(132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (180)..(180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (182)..(185)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (188)..(189)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (191)..(197)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (199)..(203)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (205)..(217)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (219)..(219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (221)..(224)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (226)..(227)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (229)..(231)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (234)..(234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (236)..(236)
<223>  n is a, c, g, or t

<400>  4666
gatgaggaac tgtggaatgc cttacaagag gtacaactta aagaaaccat tgaagatctt       60

cctggtaaaa tggatactga attagcagaa tcaggatcca attttagtgt tggacaaaga      120

caactngtgt gnccttgcca gggcaattct caggaaaaat cagatattga ttattgatgn      180

annnncgnna nnnnnnnann nnngnnnnnn nnnnnnnana nnnnannann naananaaaa      240

aaaaatccgg gagaaatttg cccactgcac cgtgctaacc attgcacaca gattgaacac      300

cattattgac agcgacaaga taatggtttt agattcagga agactgaaag aatatgatga      360

gccgtatgtt ttgctgcaaa ataaagagag cctattttac aagatggtgc aacaactggg      420

caaggcagaa gccgctgccc tcactgaaac agcaaaacag gtatacttca aaagaaatta      480

tccacatatt ggtcacactg accacatggt tacaaacact tccaatggac agccctcgac      540

cttaactatt ttcgagacag cactgtgaat ccaaccaaaa                            580


<210>  4667
<211>  498
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (142)..(142)
<223>  n is a, c, g, or t

<400>  4667
attgcagtac agcattacct acatgaactt gttatcaaaa cccttgtcca gcacaacctc       60

ttttatatgc tgcatcagtt cctgcagtac cacgtcctca gcgactccaa acctttggct      120

tgtctgctgt tatccctaga gngtttctat cctcctgctc atcagctatc tctggacatg      180

ctgaagcgac tttcaacagc aaatgatgaa atagtagaag ttctcctttc caaacaccaa      240

gtgttagctg ccttaaggtt tatccggggc attggtggcc atgacaacat ttctgcacga      300

aaatttttag atgctgcaaa gcagactgaa gacaacatgc ttttctatac aatattccgc      360

ttttttgaac agcgaaacca gcgtttgcga gggagcccca atttcacacc aggggaacac      420

tgtgaagaac atgttgcttt tttcaaacag atttttggag accaagctct aatgaggcct      480

acaacattct gaaatcac                                                    498


<210>  4668
<211>  391
<212>  DNA
<213>  homo sapiens

<400>  4668
attaaccaca ggcagctgtt acagaaagct gcattgtttc acattgagct gttacattag       60

ttcaggctaa atgttgggag ctccaaccac atccaagaat aaatctggaa acacactgct      120

gggatactgc tgttagagcc cttcttggcc ttgtattccc agaaatgagc tccctttcct      180

tagcttagaa gaatgtgatt atatccagga catcatgttc agaaaactta gtttactttc      240

agcatagaat gcattactgt tggaataatt ggcctctagc tcttaaatgt ctctgataac      300

ttattaatat ctatctttat aaaatagagt gcaactactt ttgtgtaaaa atgtttgcct      360

ttaaatttag tatttcatat cagcacatcg a                                     391


<210>  4669
<211>  544
<212>  DNA
<213>  homo sapiens

<400>  4669
gcaggagccc cattctcaga gaatgtgtgt gcagagtccc tgccgtttta ggacaatcag       60

ggcccatctt ctgccaagtg tctgacccca tggggttgtt ctgtgtttgc atttaagcaa      120

gtgacttctg ggaagtcccc ggccgcccgg ggttctatga tatttgtagt gccggggctc      180

gcacactgct gcccccagcc tgtagaggac tttcttcagg gcccgtagct gctgggcgta      240

cccctggcag gcgggctgtg ccgcgggcac atttgccttt tgtgaaggcc gaactcgagc      300

tgtatcctca taggaaacag tgatcacccc ggacgggcgt ccaggaccct gagggccatg      360

gccaaaaggc tcctgagtgt gcctggtggt ctggctgggg ctcacggtgg gctgtctggg      420

gagggtgggt gcctccacta tgatccttaa aggattcctc tgtgtgggtg gatgcgtgtg      480

ggcacgactt tgtactcaga aattgaactc tcagtcacgt ggaagccacg ggactgctcc      540

gaag                                                                   544


<210>  4670
<211>  309
<212>  DNA
<213>  homo sapiens

<400>  4670
agggggtcga tcctctgaag cttgagatct atctcaccga cgaagacttc gagtttgcac       60

tagacatgac gagggatgaa tacaacgccc tgcccgcctg gaagcaggtg aacctgaaga      120

aagcaaaagg cctgttctga gtggggagac gccagaggag cctcacggtc acgtccaaca      180

acaccactgc accagggaaa tggatatata tttttggact ggtgtttttc acaaagtatt      240

tttcaatcag agttttcaga acctgacatt gttaaagata ctgcttgtcc cggagttgtg      300

tattttgta                                                              309


<210>  4671
<211>  244
<212>  DNA
<213>  homo sapiens

<400>  4671
cttttcccca ctcttaaata ctgtactact tcactgtaag aacgaaagaa tagttaggat       60

accaatgagt aaaagggttc ctgttcactc tgactctgtg caaattgtat tacagtagac      120

cgctgacgtt cccaagtgac agatccaggg cctttcaaac atccccaaag tcatggccat      180

actcaccatt agccagtttc taacatctgt ttcagggtat ccagctgtag atgttcttat      240

cccc                                                                   244


<210>  4672
<211>  399
<212>  DNA
<213>  homo sapiens

<400>  4672
tggcccagcg ccaagtaaac agggtacctc aagccccatt tcctcacact aagagggcag       60

actgtgaact tgactgggtg agacccaaag cggtccctgt ccctctagtg ccttctttag      120

accctcgggc cccatcctca tccctgactg gccaaaccct tgctttcctg ggcctttgca      180

agatgcttgg ttgtgttgag gtttttaaat atatattttg tactttgtgg agagaatgtg      240

tgtgtgtggc agggggcccc gccagggctg gggacagagg gtgtcaaaca ttcgtgagct      300

ggggactcag ggaccggtgc tgcaggagtg tcctgcccat gccccagtcg gccccatctc      360

tcatcctttt ggataagttt ctattctgtc agtgttaaa                             399


<210>  4673
<211>  371
<212>  DNA
<213>  homo sapiens

<400>  4673
aggaggagtt gaaagctctg ctgttgtctc accctatctt aatgagagac aagtgaggtg       60

gagggcctgc cccccctccc tccaccagac actccttcca ggcctgagcc ccaacccctc      120

ttcaggcctt ccttccctag ctgtgtcttg gtcttcaatc ccagaacagg acctgtgagc      180

agctgcattg gcctggagct ggagagtaag gctgtaggat ctttggaatc tcttggttcc      240

taagagtttc ctcagagatc atacctcccc agagggaagc aggaatgagg ccaaaaagtg      300

tgcattggat aggggaacag caggcagggc tctgggtgac gcatgcctct ggtctaataa      360

actgggtttc a                                                           371


<210>  4674
<211>  377
<212>  DNA
<213>  homo sapiens

<400>  4674
catgcccggg ctgaaatatt tctcgtaata gcagaatatt tcatggccga actcttgata       60

gtgacaaatc agtaaataca accaagaaaa agaaaatgag gggtcagagt tgcaataccc      120

caaatgaaaa ataacagttt tttcagggct ttttggtacc agaactcagg cacttggatt      180

ttatgacctt atactttttc tgcatctctc taaaacttgt gttttcagac catcctgtgt      240

atagagcagg agagtttcta ctgcaagtga caatcagagg tgactatcta tatttgcact      300

taaaatcaaa gtagttcaac atgcaaatgc tagggtctag ccctgggtaa gggccatgct      360

ggtgtactgt gttgtga                                                     377


<210>  4675
<211>  332
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (248)..(248)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (283)..(283)
<223>  n is a, c, g, or t

<400>  4675
aagggtgtcc ttctaatttc aaaatatcaa ctcctaagag gtcagcagaa tttggagatt       60

tgggtcctta taagaatagc tggtgctctt ttcttgttca tgtctcaaaa caaagctgtt      120

gagagaactg ctgcgatgaa tcaaaccaga ggagtttgtc atgctcccca cagagagccc      180

aggacatttg cctgatgtat ggtgctgagc tccaccttca gaggaactct ctcttttttt      240

tttttttnaa ataactatta ttagcttgac aagaaaaaaa aangtgccca acagttttag      300

tgttaatctt ggtgctctat ggtgcattag ca                                    332


<210>  4676
<211>  381
<212>  DNA
<213>  homo sapiens

<400>  4676
aagatctgaa gtttggtatt tttgcattat gacagttgtt gagactagga ttttaagcta       60

ggatatgatt atatttccta tataactaaa aattttgttt cataaatttt aaaataatta      120

tttttgacta tgaacattag tccaaattta atatttgaca cagttcatac cagcttgcta      180

caataatgat aatttattag tctttctgtt atttaaagaa taaaaacatg cttataaaag      240

acttttaatg aaatgttgcc tttttaaaat aattatactt gcacatgaaa ataaaatata      300

aagtcaataa tagtccttgt agcccaatgg gaattgattc tgtttattgt ctgtaccatt      360

ttgctaccag ttacattgaa c                                                381


<210>  4677
<211>  243
<212>  DNA
<213>  homo sapiens

<400>  4677
tgggctgtgt gtgcgacgcg ggtcggaggg gcagtcgggg gaaccgcgaa gaagccgagg       60

agcccggagc cccgcgtgac gctcctctct cagtccaaaa gcggcttttg gttcggcgca      120

gagagacccg ggggtctagc ttttcctcga aaagcgccgc cctgcccttg gccccgagaa      180

cagacaaaga gcaccgcagg gccgatcacg ctgggggcgc tgaggccggc catggtcatg      240

gaa                                                                    243


<210>  4678
<211>  408
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (135)..(135)
<223>  n is a, c, g, or t

<400>  4678
agaccaggtg ccttgccgca gagaaaacac caaagtctcc tgttcgctca taaagaagtt       60

tttgggatgg gagagaatcc agaccatctt ggggcagcca ggcccttgcc ttcattttta      120

cagaggtagc acaantgatt ccaacacaaa actccttccc ctttttaaaa tgatttctgt      180

tctaatgcca tagatcaaag gcctcagaaa ccattgtgtg tttcctcttt gaagcaatga      240

caagcacttt actttcacgg tggtttttgt tttttcttat tgctgtggaa cctcttttgg      300

aggacgttaa aggcgtgttt tacttgtttt tttaagagtg tgtgatgtgt gttttgtaga      360

tttcttgaca gtgctgtaat acagacggca atgcaatagc ctatttaa                   408


<210>  4679
<211>  241
<212>  DNA
<213>  homo sapiens

<400>  4679
gaatataaaa tccaaagtct gaccagtttg taaagaaaaa caaatggtaa ctggtgctta       60

aagctgatca agaaagttaa caacaacata gaaaccacac gattgttcca ctgtctggaa      120

gcaccatccc ctatcgcagg actcctgggc cacaagcagt cggtcagtgc agacttcaag      180

tgtgtctgtt tgatgtggtg tgattgtgct ggccttgtcg aaaaagatgt gatgcttctc      240

a                                                                      241


<210>  4680
<211>  246
<212>  DNA
<213>  homo sapiens

<400>  4680
ctctgaagat gagcccgtgg gccagcgggg gtcacttcat gaatacggct gagcggatcc       60

ggctgcctga tgactgcacc atcggctaca tcgtggaggc cctgctgggt gtgcccctca      120

tccgcagcgg cctcttccac tcccacctgg agaacctgca gcaggtgccc acctcggagc      180

tccacgagca ggtgacgctg agctacggta tgtttgaaaa caagcggaac gccgtccacg      240

tgaagg                                                                 246


<210>  4681
<211>  538
<212>  DNA
<213>  homo sapiens

<400>  4681
aaggtggcgg gaactcagct tcaacctcga tgtcttcagg gtcttgtcca gaatgtagat       60

gggttccgta agaggcctgg tgctctctta ctctttcatc cacgtgcact tgtgcggcat      120

ctgcagttta caggaacggc tccttcccta aaatgagaag tccaaggtca tctctggccc      180

agtgaccaca gagagatctg cacctcccgg acttcaggcc tgcctttcca gcgagaattc      240

ttcatcctcc acggttcact agctcctacc tgaagaggaa agggggccat ttgacctgac      300

atgtcaggaa agccctaaac tgaatgtttg cgcctgggct gcagaagcca gggtgcatga      360

ccaggctgcg tggacgttat actgtcttcc cccacccccg gggaggggaa gcttgagctg      420

ctgctgtcac tcctccaccg agggaggcct cacaaaccac aggacgctgc aacgggtcag      480

gctggcgggc ccggcgtgct catcatctct gccccaggtg tacggtttct ctctgaca        538


<210>  4682
<211>  232
<212>  DNA
<213>  homo sapiens

<400>  4682
gaaggtaccc aaccctctgg gatagatgca ggaagcgatg gttaagaccc attttcaccc       60

aacttctcgc cgcaggtctg gcttaccaca cgctcctccc cattcccagt gagccgcttt      120

ttgcagcacc aggcgaacac ttacaccagt gctttgtaaa ggaatcttat tgtccacccc      180

gtgtcttggc aaaagaacag tgatcacaca gattcctact tgggctcttt cc              232


<210>  4683
<211>  465
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (79)..(79)
<223>  n is a, c, g, or t

<400>  4683
acattcctac tgttaaaaag gccagtatat cttaaacaaa tgaataggca tgaggcatat       60

tcagttgact tacaatgana aagttataca gacaacagta ataactaaaa gggtgaatct      120

gctaaatcct tttgaaatgc tgcagatttg ataaatattt attttagact aattggtttt      180

aggtgaattg gttttaggca aattaattta gtaatctttg atctttagtc ttcattttct      240

gtcactcagt gagtttctta ctggaaatga tgactcctga caacagaatt tccacatttg      300

ggggctattc taaggtgact atgccagcca acctgggaaa tacataaaag agatctctga      360

gtgagaggga aagaggtcag atttatacaa ctgagcgcca gaggggaaaa tgcaccttgt      420

tggagtgaga aatgttctga aactgaatta cttcttgtac agctg                      465


<210>  4684
<211>  516
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (107)..(107)
<223>  n is a, c, g, or t

<400>  4684
aggaattcca cacccttgtg ttgcgcccgg agcccgccct tcgcctccca gcccctcaag       60

acaccgctgg ctgctggaca ccctcttcac ttgtgtgtgt gtgtgtnagc ggaaaaggac      120

aagacggtgc agtcggctgc atactcccag tcgggagtgt ggtcagtctg cctgctgctg      180

tgcggtagct ccagaaccac ctcgttcctg gttttgtttg gattttggca tcttgttttt      240

ctaacaacaa acaatggaga aaaagaattg attcttagtg acacagaaga ttgccttacg      300

ctcgtgagcg tgagaagcca taagagagag accgaattct gtggctcagc acacaggact      360

gacccacagc ccaggcagcg ggtgtgtgga gatggcgccc tgtcctgcca aggggcgcca      420

ggagcagagc cagggcctgg cgagctggcg tggagcccac aggattcagc agcatggaca      480

gtcactcttg cactattcct tctccaagcc agaaac                                516


<210>  4685
<211>  210
<212>  DNA
<213>  homo sapiens

<400>  4685
aggacagcct gtcatcactg ggaaagaggc cagaagagcc gtttggccag ggtctccaat       60

ttaggctttc aacattatct ctaaagaagg ttatacatta tgtcggctcc actggctgat      120

gggatcaaag accctccttg tatatcctta aacctgtact ctattaccag gccactgtgc      180

ctgtggagca ctgtaagttc ctacctttta                                       210


<210>  4686
<211>  538
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (49)..(49)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (57)..(57)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (122)..(122)
<223>  n is a, c, g, or t

<400>  4686
aagagcttta tcaagaacta tcctgtggtc tccatcgaag acccctttng accaggnatg       60

actgggccac ttggacctcc ttcctctcgg gggtgaacat ccagattgtg ggggatgact      120

tnacagtcac caaccccaag aggattgccc aggccgttga gaagaaggcc tgcaactgtc      180

tgctgctgaa ggtcaaccag atcggctcgg tgaccgaatc gatccaggcg tgcaaactgg      240

ctcagtctaa tggctggggg gtgatggtga gccaccgctc tggggagact gaggacacat      300

tcattgctga ccttgtggtg gggctctgca caggacagat caagactggc gccccctgcc      360

gctcggagcg tctggccaaa tacaaccaac tcatgaggat cgaggaggct cttggggaca      420

aggcaatctt tgctggacgc aagttccgta acccgaaggc caagtgagaa gctggaggct      480

ccaggactcc actggacaga cccaggtctt ccagacctgc ttcctgaaat aaacactg        538


<210>  4687
<211>  73
<212>  DNA
<213>  homo sapiens

<400>  4687
agcaggccaa ggctgtgctc aagcatttca acgtgcgtgt cacccacgca gacatcttca       60

gccgctgcca ggc                                                          73


<210>  4688
<211>  180
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (60)..(60)
<223>  n is a, c, g, or t

<400>  4688
taatttaacc agaactgcat tatattcaat aacggatttt ctttataaca aacaacaggn       60

gaaaatggag ttggcacaca gtggatcact ttgatatttt taatagtcca agtctggatt      120

ttatttattc ctgagccaac aattttgaac agcatatttt ccatgtttct gactgtaaca      180


<210>  4689
<211>  445
<212>  DNA
<213>  homo sapiens

<400>  4689
gcaacagggt aaggtcctgt ctctacaaga tcaaaaactt agccgggtat ggtggtgcat       60

gtgtgcctgt agtccaagct acttgaaggc tgagacagga ggatcggttg agcccaggag      120

gttgtggctg cagtgagctg tgatgtgccc ttatgctata gcctgggcaa gagcgtgaga      180

ccctgtctca aagaagaaaa aaagagaaaa ataactcttt tgaacaaaca gacaaattag      240

ctagtagtat ggagatgtat accctctatt acacacataa aaccgtaaca aaattcattg      300

tggtgtatta taattagttt tgtgaataga aaaataaagc acttatgttt aaatttgtta      360

cagtgacttt taaaggatta atgttgaatc acattgtcag aattttttcc tcctcgctgt      420

tcaattttgt agtttttact ctcaa                                            445


<210>  4690
<211>  355
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (167)..(167)
<223>  n is a, c, g, or t

<400>  4690
gccctgcatg tgacggagcg caaatacctg aagcgagact ggtgcaaaac ccagccgctt       60

aagcagacca tccacgagga aggctgcaac agtcgcacca tcatcaaccg cttctgttac      120

ggccagtgca actctttcta catccccagg cacatccgga aggaggnaag gttcctttca      180

gtcctgctcc ttctgcaagc ccaagaaatt cactaccatg atggtcacac tcaactgccc      240

tgaactacag ccacctacca agaagaagag agtcacacgt gtgaagcagt gtcgttgcat      300

atccatcgat ttggattaag ccaaatccag gtgcacccag catgtcctag gaatg           355


<210>  4691
<211>  328
<212>  DNA
<213>  homo sapiens

<400>  4691
tgtttgtttg ccctctcatt tttcagtact tctacagaat tttctctaga gtcagtcatt       60

atgaaatgta cttccctcca tcttaaccta tcaactttct gcccctcctt caaggcccag      120

tataaatgcc acctcctcca tgaagccttc cctaattcca ccccaaaccc ccaccttcaa      180

caatatttca acgcttctgc aatgatgaaa aagaaacata gttgtagtac ttagcctacc      240

tagaccagca agcattcatt tttagctcgc tcatttttta ccatgttttc cagtctgttt      300

aacttctgca gtgccttcac tacactgc                                         328


<210>  4692
<211>  433
<212>  DNA
<213>  homo sapiens

<400>  4692
tgaggtagat tgctgtcccg ttaacatagt gctgaaacca aaggcagtgg gggtccaaac       60

tcgtggtgca gcaagtcaca ccagacagga aacgaatatg gacgtaattg cagaaggaac      120

ttcaaggaga tgaatgaatg ctaaaagggt tcttgactga tccattgcta acagcctgag      180

actcttcaat gcctttccga aaactggttt ctagtaaagc cttgaatgaa cacacacaca      240

cacacacaca cacacacaca cacacacaca cacacacaca ccgtcctaca ctttaagctg      300

ctcctttggt atgactctat acttatggaa atgtagaaac aaacattttt aaatagctgc      360

tgtacttttc acattttgat ttattaggta ctagcactga ggaaaaaaaa ttcagcactt      420

ggactatcat agg                                                         433


<210>  4693
<211>  445
<212>  DNA
<213>  homo sapiens

<400>  4693
ggaaagtgtt gctgcgacac cacctccatc accttcgctc cctgctaagc ctaagcctcc       60

ttcgagaaga gacccaactc caacctattc tgcaacagaa gacactttta aagacaccgc      120

aaatcttgtt aaagaagact ctgaagtata gctataccag ctatttaggg aataattaga      180

aacacacttt tgcacatata ttttttacaa acagatgaaa aaagttaaca ttcagtactt      240

tatgaaaaaa atatattttt ccctgtttgc ctatagttgg aggtatcctg tgtgtctttt      300

tttacttatg ccgtctcata tttttacaaa taattatcac aatgtactat atgtatatct      360

ttgcactgaa gttgtctgaa ggtaatacta taaatatatt gtatatttgt aaattttgga      420

aagattatcc tgttactgaa tttgc                                            445


<210>  4694
<211>  452
<212>  DNA
<213>  homo sapiens

<400>  4694
gaatttttat atctgagtgt tcaaaatatt tccaagcctg agtattgtct attggtatag       60

atttttagaa atcaataatt gattatttat ttgcacttat tacaatgcct gaaaaagtgc      120

accacatgga tgttaagtag aaattcaaga aagtaagatg tcttcagcaa ctcagtaaaa      180

ccttacgcca ccttttggtt tgtaaaaggt tttttataca tttcaaacag gttgcacaaa      240

agttaaaata atggggtctt ttataaatcc aaagtactgt gaaaacattt tacatatttt      300

ttaaatcttc tgactaatgc taaaacgtaa tctaattaaa tttcatacag ttactgcagt      360

aagcattagg aagtgaatat gatatacaaa atagtttata aagactctat agtttctata      420

atttatttta ctggcaaatg tcatgcaaca at                                    452


<210>  4695
<211>  48
<212>  DNA
<213>  homo sapiens

<400>  4695
gcggcaaaca tgcacgcgca gatcaagacg agcctgcacc gcctgaag                    48


<210>  4696
<211>  454
<212>  DNA
<213>  homo sapiens

<400>  4696
agaacaccac ataccttgtc cggaacatta caatggcttc tgcatgcatg ggaagtgtga       60

gcattctatc aatatgcagg agccatcttg caggtgtgat gctggttata ctggacaaca      120

ctgtgaaaaa aaggactaca gtgttctata cgttgttccc ggtcctgtac gatttcagta      180

tgtcttaatc gcagctgtga ttggaacaat tcagattgct gtcatctgtg tggtggtcct      240

ctgcatcaca aggaaatgcc ccagaagcaa cagaattcac agacagaagc aaaatacagg      300

gcactacagt tcagacaata caacaagagc gtccacgagg ttaatctaaa gggagcatgt      360

ttcacagtgg ctggactacc gagagcttgg actacacaat acagtattat agacaaaaga      420

ataagacaag agatctacac atgttgcctt gcat                                  454


<210>  4697
<211>  315
<212>  DNA
<213>  homo sapiens

<400>  4697
aagtcttatt tcctcaacgt tgctccccat caagcccttt acttgacctc ctaacaagta       60

gcaccctgga ttgatcggag cctcctctct caaactgggg cctccctggt cccttggaga      120

caaaatctta aatgccaggc ctggcaagtg ggtgaaagat ggaacttgct gctgagtgca      180

ccacttcaag tgaccaccag gaggtgctat cgcaccactg tgtatttaac tgccttgtgt      240

acagttattt atgcctctgt atttaaaaaa ctaacaccca gtctgttccc catggccact      300

tgggtcttcc ctgta                                                       315


<210>  4698
<211>  94
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (58)..(58)
<223>  n is a, c, g, or t

<400>  4698
tttataagaa cagtacagat tgttctcaag agggccatca gaaggaagcc aaagagtnca       60

cagcctcagc accaacaact caacatggtc atca                                   94


<210>  4699
<211>  225
<212>  DNA
<213>  homo sapiens

<400>  4699
gaaggcggcg tgttgtgtga gcgagagggt agcggatgtg tgtgtgcgtg tgcgcgcgtg       60

gctccgggtg tgcgccgctg cgatagcggg tcctttcccg gggcgggcga cgggcgggct      120

gggaaggtct cctcccctca ccacattgag aaatctcagt gagtcaccga gtggttctgc      180

atattaatga gctcgctcgc tgcgagggca ggagcggatt taaaa                      225


<210>  4700
<211>  551
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (475)..(475)
<223>  n is a, c, g, or t

<400>  4700
gggaccaatc atcagactcc ttgaactccc ccactctgct ggctctgtaa cccagtgcac       60

ctccctcccc agctccggag ggggtcctcc tcgctcctcc ttcccaggga ccagcacctt      120

caagcgctcc agggccgtga gggcaagagg gggacctgcc accagggagc ttcctggctc      180

tgggggaccc aggtgggact tagcagtgag tattggaaga cttgggttga tctcttagaa      240

gccatgggac ctcctccctc attcatcttg caagcaaatc ccatttcttg aaaagccttg      300

gagaactcgg tttggtagac ttggacatct ctctggcttc tgaagagcct gaagctggcc      360

tggaccattc ctgtcccttt gttaccatac tgtctctgga gtgatggtgt ccttccctgc      420

cccaccacgc atgctcagtg ccttttggtt tcaccttccc tcgacttgac ccttncctcc      480

cccagcgtca gtttcactcc ctcttggttt ttatcaaatt tgccatgaca tttcatctgg      540

gtggtctgaa t                                                           551


<210>  4701
<211>  485
<212>  DNA
<213>  homo sapiens

<400>  4701
acaattgaca atctggacta ccccaagatg gcacccaagt gtttggcttc tggctaccta       60

aggttaacat gtcactagag tatttttatg agagacaaac attataaaaa tctgatggca      120

aaagcaaaac aaaatggaaa gtaggggagg tggatgtgac aacaacttcc aaattggctc      180

tttggaggcg agaggaaggg gagaacttgg agaatagttt ttgctttggg ggtagaggct      240

tcttagattc tcccagcatc cgcctttccc tttagccagt ctgctgtcct gaaacccaga      300

agtgatggag agaaaccaac aagagatctc gaaccctgtc tagaaggaat gtatttgttg      360

ctaaatttcg tagcactgtt tacagttttc ctccatgtta tttatgaatt ttatattccg      420

tgaatgtata ttgtcttgta atgttgcata atgttcactt tttatagtgt gtcctttatt      480

ctaaa                                                                  485


<210>  4702
<211>  423
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (368)..(369)
<223>  n is a, c, g, or t

<400>  4702
ttatttactg ccacgctact gatattcaga ccttcatgat catccatctg gtgagcagag       60

cttcatttgt atataacact ttcagagcct tcccacccat aggtagttct taaaccaggt      120

gaaagagcaa agttcaagtg cctacttatg tgtcattcgc tcatgtaaga gtttttaaga      180

gagggctgat tatcacagcc ctcttttctc ctgaattttt aatgcagaag tttgaatgaa      240

gcaagggaag gcatgtaggg acaggaaagg aaacaatgga aggaaagtga ttctgtgaaa      300

aggacagtga agccagctat tttaccccca ggctggattt tttttttttt tttttttttt      360

tttttttnna ccgagtacac agagtaccca agtgaagaga acgtcatgag tgtaagtgca      420

aat                                                                    423


<210>  4703
<211>  494
<212>  DNA
<213>  homo sapiens

<400>  4703
tgaaactaca actctcacgt gtgctccagt tctaaaatta acctgtgcct ggtctctgaa       60

gccctttctt gctctgtgcc tttcagccac atccttaggt gctaacggcc atgagctccg      120

actctccaaa gtgagctcca ctttgggtct gaggagcccc tggcagagtc cacgctgcct      180

caggtatcat gggcgtaatg atcacccagg ctccgggaga tctcatggat gattactgta      240

tgagacagag gggacttcag tctttccagg gccttggtgg aatttttggc tctggtgttt      300

tcgccagaca ataaacttac actggaagct ttgattcacc ctccacagta ctccagaaag      360

gactgtccta taagttgtac actttaaaag gtcatgtaga ggttgtagta gaatggcttt      420

tcaccctggt gactttggaa gaaactcttg aatactgcct gcatccgggc accatggcca      480

ggttgcctag gagt                                                        494


<210>  4704
<211>  542
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (389)..(389)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (399)..(399)
<223>  n is a, c, g, or t

<400>  4704
gagtcagtgt ggacctcatg attatagagg ccaatggaac tggtcagtga ttctctaccc       60

caagtaggga aaacctccat cttttccctg tcttcatcct gttatcccct ggtgtacaca      120

tggaagagga ccaggacata ccacctgggg atgggctgac tcagggtccc gaggccagag      180

acaaagctgt gggagccaag aataagacag aaggcatcag atatttgcct ggctctggtc      240

acttcccttt gaagttgact tcaagcttag cttcctcaac tactgttttt cagaaggaag      300

aaagaatcaa atggaagaag aatcaagtcc atgcccaagc ccaaagcctg cacacattct      360

gcccttaatc caagtgttgc ctataaaant attttctgnt ttctcactct agttccccca      420

aagctgtagt cccaatcaat caaaggctac caactgagtc ctcaggttca tttctttttt      480

tttttttttt ctttttaact ctcctggtaa ctcacagaac agctcaggtt catttctagg      540

tg                                                                     542


<210>  4705
<211>  133
<212>  DNA
<213>  homo sapiens

<400>  4705
tttgatgtga tgattcactt ttcagttctc aaattaaaag aaaactgtta gatgcacact       60

gttgattttc atggtggatt caagaactcc ctagtgagga gctgaacttg ctcaatctaa      120

ggctgattgt cgt                                                         133


<210>  4706
<211>  498
<212>  DNA
<213>  homo sapiens

<400>  4706
tagtgtgaca ttccaatcat ttagtatttt aggacctgtg aataacttcc aacaaaatta       60

atgaatacca tattagtatt ataaaatatt ataaagtaat aattatatca tctatataac      120

ttcaaagtat gatgtttata caaagaatcc ttatttcagt ctagcagctt aacaacaaag      180

gataaatcag actatacaaa acctaagtgt attaatttga tgattgtcac gtacaacttt      240

ctttgccttc caagtagagg tgatcctaac aattggcatg atgcttttct tggtaatttg      300

atataagcaa gttgtaatgt acatagtaat tatttaatta ctgtggcttt tattttaaaa      360

agtaattaga ggtttttcca tttcatgtct tgaacaacat taatattaat tacactagaa      420

atattttttg attcagaact tagaattgta cctgatattt ataggtattt aaatgctttc      480

tgcaagttaa atatcgag                                                    498


<210>  4707
<211>  541
<212>  DNA
<213>  homo sapiens

<400>  4707
attacactgg agctgcatac gcacaatact cagcagctgc tgctgctgcc gccgccgctg       60

ctgcctatga ccagtacccc tatgcagcct ctccagctgc tgcaggatat gttactgctg      120

ggggctatgg ctacgcagtc cagcagccaa tcaccgcagc ggcacctggg acagctgccg      180

ccgccgctgc agcagctgct gccgctgcag catttggcca gtaccagcct cagcagctgc      240

agacagaccg aatgcaatag accagccatc tgatcaaagt tgaattgttt tctctttccc      300

tcccaatttt ccaattttta gtagctaata agagagttaa cattgactta acagctttaa      360

aaaaaaaaac agccatgcta ttgtgaagca gagttattat tttttttata ctccaggtag      420

tgttctagat gagaaagagg taagaatgag gggaatgggc acaattttgg aaatcaatcc      480

caaagagcct gagtaaatga aaggccacta cgaaatgacg ccaggagtaa caacggaact      540

t                                                                      541


<210>  4708
<211>  357
<212>  DNA
<213>  homo sapiens

<400>  4708
ggacactggg agcacataga gattcaccca tgtttgttga acttagagtc attctcatgc       60

ttttctttat aattcacaca tatatgcaga gaagatatgt tcttgttaac attgtataca      120

acatagcccc aaatatagta agatctatac tagataatcc tagatgaaat gttagagatg      180

ctatatgata caactgtggc catgactgag gaaaggagct cacgcccaga gactgggctg      240

ctctcccgga ggccaaaccc aagaaggtct ggcaaagtca ggctcaggga gactctgccc      300

tgctgcagac ctcggtgtgg acacacgctg catagagctc tccttgaaaa cagaggg         357


<210>  4709
<211>  379
<212>  DNA
<213>  homo sapiens

<400>  4709
agactccacc gcagacccgc aggaggcggc gtgccaagat caccggccgg gagcgcaagg       60

ccatgagggt cctgccggtg gtggtcgggg ccttcctgct gtgctggacg cccttcttcg      120

tggtgcacat cacgcaggcg ctgtgtcctg cctgctccgt gcccccgcgg ctggtcagcg      180

ccgtcacctg gctgggctac gtcaacagcg ccctcaaccc cgtcatctac actgtcttca      240

acgccgagtt ccgcaacgtc ttccgcaagg ccctgcgtgc ctgctgctga gccgggcacc      300

cccggacgcc ccccggcctg atggccaggc ctcagggacc aaggagatgg ggagggcgct      360

tttgtacgtt aattaaaca                                                   379


<210>  4710
<211>  519
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (484)..(484)
<223>  n is a, c, g, or t

<400>  4710
ttgtctgtgt caggacagtg tccctccctg ggaaatgtga catgagggcc gactggggcc       60

aggctcaggg gcagaggctg ggacacaagg ggctggcgag ggctgcgagg ccagggaagc      120

cctgagtttc tggcggggct gagcagtggg ggagcattgt gttgtgggtg tctgtgtgtg      180

aggtcaccct caaactgcac cgccggccag ataccctcct gaccccgagg acttggtctg      240

gtctctctgg tggctacaac cccagagttt taaggacttg gaaaggaaag cacaatcaga      300

gaagaaaaca gcccccgaac cagcaggagt ggcctggcac atggaccggc ctgagcgatg      360

tgcactccac ccaagccagg ctcccagggg gcctgatttc tctctcactg tctctttttt      420

taaaatggtt gcacggctct gccccatggg gggccttttt tacacactgc gaggcccagc      480

tttnctaggg gacttttgca catgtcatgc agctcagct                             519


<210>  4711
<211>  268
<212>  DNA
<213>  homo sapiens

<400>  4711
gcgcctggct tatactttct taataaaaag gagaaagaaa atcaacaaat gtgagtcata       60

aagaagggtt agggtgatgg tccagagcaa cagttcttca agtgtactct gtaggcttct      120

gggaggtccc ttttcagggg tgtccacaaa gtcaaagcta ttttcataat aatactaaca      180

tgttatttgc cttttgaatt ctcattatct taaaattgta ttgtggagtt ttccagaggc      240

cgtgtgacat gtgattacat catctttc                                         268


<210>  4712
<211>  162
<212>  DNA
<213>  homo sapiens

<400>  4712
aatactgcaa agacactcgg cagcaacatc agcagggaga tgaatcacag aaaatgagag       60

gggactatgg caagttaaag gccctcatca atagtcggaa aagtagaaac aggaggaatc      120

agttgccaga gtcataatat tttcttatgt gggtcttatg ct                         162


<210>  4713
<211>  560
<212>  DNA
<213>  homo sapiens

<400>  4713
aaaggcagcc ctttgggtac tactgctgca aagtgcaaat actccaagct tcaagtgata       60

tatgtattta ttgtcattac tgcctttgga agaaacaggg gatcaaagtt cctgttcacc      120

ttatgtatta ttttctatag ctcttctatt taaaaaataa aaaaatacag taaagtttaa      180

aaaatacacc acgaatttgg tgtggctgta ttcagatcgt attaattatc tgatcgggat      240

aacaaaatca caagcaataa ttaggatcta tgcaattttt aaactagtaa tgggccaatt      300

aaaatatata taaatatata tttttcaacc agcattttac tacttgttac ctttcccatg      360

ctgaattatt ttgttgtgat tttgtacaga atttttaatg actttttata atgtggattt      420

cctattttaa aaccatgcag cttcatcaat ttttatacat atcagaaaag tagaattata      480

tctaatttat acaaaataat ttaactaatt taaaccagca gaaaagtgct tagaaagtta      540

ttgtgttgcc ttagcacttc                                                  560


<210>  4714
<211>  531
<212>  DNA
<213>  homo sapiens

<400>  4714
gagctaccat atgtgctgtc tattataaat gggacaccaa acaaaatttt ctattacagt       60

tgtgtacttg caaacatttt gctatacagt acttcataga tgcatacaaa tgagctcact      120

tattacaaag acaaacgttt aatttgctaa atattttaac aagtttgtta tatattttat      180

ttaatttaaa agaaatctct taccaaccta catatttatt actataattt gctatgactt      240

caggttaatt tatttgtgtt tgcatagttt gagcaggatg ttttgtgaag tatgtttgta      300

tttatttgcc tactttgtac ttgatgtgtt ttgtaatgtg cactgaattt gttttctttt      360

caactatgtt aatgatcaat actgtaaatt gggtcttttg taaacaaaaa ggcaatgatg      420

tatgcatttt ttttaatttg aggtagtttg tttgtatact gtttctccaa acacttaata      480

tttcttacat caaagcaaca aaattgtgtt cagtgctgta catttggtgt a               531


<210>  4715
<211>  380
<212>  DNA
<213>  homo sapiens

<400>  4715
ggaagccaca gcatcagtga gtgaaggtgg gggactgcag ggcatcagca tgaaggacag       60

cgatgaggaa gacgaagaag acgattagac catttggtcc tagagtctgc tgggacagag      120

tcctgtaatc agtgcatgtc cttagtctgt tagttaaacc cattaggaat tttctgtcaa      180

ctaccatgcc catgagatgt ttatcaatac aactgccatt ttagctatgt ggtaccaaga      240

ttagcaaatg accttcatat ccactgattt cctgatgtcc atgtctatat gtttacaagc      300

aatatggagc accattcttt aaatactgtt catggagaat acatagtcta accactaggc      360

gtgtccctgt tatcagcaaa                                                  380


<210>  4716
<211>  427
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (116)..(116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (119)..(119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (122)..(122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (154)..(154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (179)..(179)
<223>  n is a, c, g, or t

<400>  4716
tgagctgagc atcagtcgcc tgtgacgtgg ccaccttctg tcctgctccc actcccgacc       60

catgctggac cccggaggac ctcctgcccc gcccccacca cacacccata tccccncanc      120

anttccaatt tgttctttcc cgtggggaat tttnttttcc cagcgtctcc atcccttcnt      180

acatatccac acacacacaa attggtctga tcttttttcc attggttaaa catttaactc      240

catgccagac cttgttttaa cccctctcac atcatgttct ttcctttttt gcgagttatt      300

ttgcattaac caactttgtc agtgacagat gcgtatctga gggtgtcaca cacgaccttc      360

agcagggaag acttctgggc catggagggc cgtctaatac atggacttat aaactgactg      420

catgagc                                                                427


<210>  4717
<211>  542
<212>  DNA
<213>  homo sapiens

<400>  4717
aatagcatac acctaatgtt gggttaggga attgcaattt ctactttcat agagtcatag       60

aattttaggt ggggaagagg cattttgctt gtcatttctt aatataactc aacaagaatt      120

gcaacatttg tgtaccaagc aataagtgca atgcataaaa tttcctgtct gtatattacc      180

ttcattttgc ttgtagtagc tgtttgggtg gttggaataa ttttattttt cttttaaaaa      240

agctaacatc agaccccttt ataatgtcct aaaattatga taatacattt cccaattcaa      300

ctcaaaatat tattggtgta ttttgtctat tctggatatt tgatctgttc aatgtactgt      360

gctagtgact ggaggccctg ctactgcaaa tataaaacat aaagtttgtt taaaaaaatg      420

caaatcattc tttaccttaa gaaaaaaaaa ataccctttg ctttgtgcct caaagtgatg      480

taatgtgatc acagcttttg ttgtgttgaa tgaaaatatg tggactgtca ttttgttgca      540

gc                                                                     542


<210>  4718
<211>  87
<212>  DNA
<213>  homo sapiens

<400>  4718
gttcctcctt gacaaaagta gctctgtgtg gataatatga ttttattact acagttccag       60

tcacttggtt atatttatct tagcatg                                           87


<210>  4719
<211>  324
<212>  DNA
<213>  homo sapiens

<400>  4719
atttgagatg tggtactgct tcctcacaag tctcccacag gccatgtaaa gggtattttt       60

ttgtggcttg ctgtgttgct gagatcatcg tatgcaacag ctgggtaata agactagcat      120

agctcaaact atcctgccaa acgctctcat ctgatttttc ctcccttctc ccccaacctc      180

caatcaccct gagtcacctg taaattcatt tgtcattcaa agcggaataa caagttgtcc      240

ctagcaaaac cgctgagcgc tttataattt tgtggtgtat ttttgtcagt aggtagcaga      300

ggcggaagta ttttttggtg taat                                             324


<210>  4720
<211>  317
<212>  DNA
<213>  homo sapiens

<400>  4720
tgacagcttc atgaatccgg cggcgccctc caaccacatg aacccggtca gcaacggcct       60

gtctcctcag gtgatgagca tcttgggcaa ccccagtgcg gtgcccccgc agccacaggc      120

tgacttctcc atctccccgc tgcatggcgg cctggactcg gccacctcca tctcagccag      180

ctgcagccag cgggccgact ccatcaagcc aggagacagc ctgcccacct cccaggccta      240

ctgcccaccc acctacagca ccaccggcta cagcgtggac cccgtggccg gctatcagta      300

cggccagtac ggccaga                                                     317


<210>  4721
<211>  440
<212>  DNA
<213>  homo sapiens

<400>  4721
agccccttaa ctgtttctga aggaatgaac ggtcagccgg gaaggtgtcc ggcttagacc       60

ttgacaacag acactaccca tctgtcagcc atgtgcagtg gttagaactc ttcttgaaag      120

tccaaagagc ctttaaaatg tgtataattt gtgttttgtt gcttctattt ctattgatta      180

gatgaaaaga cattctggcc ctctgatcct ctttcttctc cacaaaagtt ttacaaataa      240

aagatgttcc cctaaataca gaatatggct ttaagaagaa aatgaaatga agaattaaat      300

taagatttca gtgttggggg aaaaaataca gcttctggat gactggattg cataacattg      360

ccctggcctc acattgtact aggatgcagc ttaaatgaag tcatctctaa atctactaac      420

ctttcacctt cttatcaaaa                                                  440


<210>  4722
<211>  498
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (66)..(66)
<223>  n is a, c, g, or t

<400>  4722
catcaaacat gttgggacaa tgcccatagg aatggacctc cttccccgtc tccagctggg       60

actggngttt ttttagtctc tggagtatga tggttctcat gggtaggatg agatctttgg      120

cagaaaggtc ttcggtggtg ctctgagcct gcgctgcata ggactgagca gacccacctc      180

ctccagcttg ggtggccctg ccactcctgg ttccaagtct ctcctttcct ggcaggtctt      240

aagggaagat tgtacccctc accctttaca tacccagaat catcagtatg tcacttccta      300

atttctatca gtgtatctca ttatttcata ctgttttact aatcctaagt ctaaacagat      360

ttgctcaaaa ggagaccatt ctatttttta aagtacttag tgatacacgt ataagctttg      420

catggacgaa ttaaataagc acattgacct tttcttgtac attcagaacc tgaacatcca      480

tgtgaaaact gggtccat                                                    498


<210>  4723
<211>  182
<212>  DNA
<213>  homo sapiens

<400>  4723
catcattgaa gcgtgactgc ctgtctgcag ggagaaggat tccatttttc ttctcagctg       60

gtccccaggc ccacgggcac agggagaggg acaactgcag cagtggggag gaggcacagc      120

tagctgcaca gttctctctt ctccttgtcc tagtcagatg aaggaggctg cactacaaac      180

cc                                                                     182


<210>  4724
<211>  479
<212>  DNA
<213>  homo sapiens

<400>  4724
ttattttctt gctttcacgg gtattattgc caagaaaatc gtagggaaaa actttaaact       60

tttcttttca gttgatccct ttgacatcac ctctcatgtt taaaatcagg aaaacacacc      120

cctaaaattt gcactctctt ccgttttgaa aaagaaaacc cacacacaaa tgcacactat      180

taccgtcttt caccctgcgc tatatttcca aagtgtatta taatccagat attgccccat      240

ctcaaacatg ttaagtcaga ctgtgctgaa agactttcca gggacggtca acagggtata      300

tgttcagtgg ctgccctgaa atcctggtgg ggatgaggat cacgcttcat catcaagggg      360

atgcccatcc cctgataagc tcccagtcct tttggaagat ttctttgaat gttaattgca      420

ttttcagttt tgctcatttc ccaccccaat gttttgtctg caacatcgct tacactgga       479


<210>  4725
<211>  484
<212>  DNA
<213>  homo sapiens

<400>  4725
gcagataatt atccaggctt aaagtaatag cttacatgtt ttgaaaatcc ttgtacttat       60

ttttgttttt attgttgcaa aaaaatgtta atgggctgtt gaaatgacct ccatttactt      120

aaggtaatcc aataaggtct tttttaaata tacaaatttt actcaagttt aaattgtata      180

aaactgctta gaaacctgaa attttatagt gtgtaatatc ttatgtgtat atagcatcct      240

gagctgtgtg atacagtaga tttcttctta gcagaaacat gcgaggtaga tttaataaac      300

aacaaaaatc agcttatgtt tctacttatt gaatctgctt tactttttag caattttctt      360

ccttgtgaac atgaaccata taaagtgtct gtgacttaat gatttcatgt aagtctgtcg      420

catacatcct tcttttgtag cttacaccat gtggatgctc tgtctgtaga cactgcttga      480

taaa                                                                   484


<210>  4726
<211>  203
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (61)..(61)
<223>  n is a, c, g, or t

<400>  4726
aaatattgga ttggctttgg aagaattata ttaggtagaa tacacataca atcaaaattt       60

naaaaaaaaa agctaaataa cttaaaaaaa aactgaggcg tacaacggag caacaatatc      120

ggttctcagt gtctatttca agatacattt ggagacaacc gtccggattt tccacttcgg      180

ttctttcgag tttagtaata ctg                                              203


<210>  4727
<211>  332
<212>  DNA
<213>  homo sapiens

<400>  4727
tgcttacgcc tttccttttc ttgctccttc ttcaactcct ggtgtgtgtg agcatgccct       60

ttgcttgcca caccatatcc tttccccaga tccacctgtc ctgacactct agtcctccag      120

gatagtgctc ctcccccagc tccagggctc ctggatgtcc ttcctcaact ccctccaccc      180

ctagacaatc ctacctggtc ccatctgcct cttttctctc cccagcctgc cctgtgaccc      240

ttgcctcttc ctgatactcc caagagcagg ccccaggggt ctgtgtcaca tatctctgtg      300

tgattccttc tggttgcatc cccaatttca ta                                    332


<210>  4728
<211>  336
<212>  DNA
<213>  homo sapiens

<400>  4728
tttcctgggc aggtttatgt tgatgtttac ccactacaat tttttaaaaa tataagctca       60

catgcctttt ccctgccaca gccaaacccc cactgcaccc tacccaccca cccctagccc      120

aggtcagctt tcctggagct ggctaatcaa agcctcctca cctcttccca acccttacaa      180

gcaagggtgc taggggctca gctatacgac cattctccct gacagggagt ccaaacttgg      240

cctagcatcc ctcctggccc ccctctggcc acgacttggc ctgtgcctgg ttctctatca      300

gaaaggggat gctgaacaaa acctccttcc aagttt                                336


<210>  4729
<211>  566
<212>  DNA
<213>  homo sapiens

<400>  4729
cagaaccggc gctccaagga gcggaggatg aagcagctga gcgccctggg cgcccggcgc       60

cacgccttct tccgcagtcc gcgccggatg cggccgctgg tggaccgcct ggagccgggc      120

gagctcatcc ccaatggtcc cttctccttc tacggagatt accagagcga gtactacggg      180

cccgggggca actacgactt cttcccgcaa ggccccccgt cctcgcaggc ccagacacca      240

gtggacctac ccttcgtgcc gtcatctggg ccgtccggga cgcccctggg tggcctggag      300

cacccgctgc cgggccacca cccgtcgagc gaggcgcagc ggtttaccga catcctggcg      360

cacccacccg gggactcgcc cagccccgag cccagcctgc ccgggcctct gcactccatg      420

tcggccgagg tcttcggacc cagcccgccc ttctcgtcgc tgtcggtcaa cggtggggcg      480

agctacggaa accacctgtc ccaccccccc gaaatgaacg aggcggccgt gtggtagcgg      540

ggtctcgcac ggtctgcgga gttcgt                                           566


<210>  4730
<211>  298
<212>  DNA
<213>  homo sapiens

<400>  4730
tcagtctcag ttcagaaaat tccagaagaa gaaggctggg tctcagtcct agtgggagaa       60

ccccctccta gtccacctga aaacaccaaa ttcaaccatc atctgtcaag aaattaaaag      120

aacaacaccc tagagagaag tcatccacac acaatccaca cacgcatagc aaacctccaa      180

tgcatgtaca gaaacctgtg atatttatac ccttgtagga aggtatagac aatggaattg      240

tgagtagctt aatctctatg tttctctcca ttttcattcc tcctgcaact attttcct        298


<210>  4731
<211>  564
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (286)..(286)
<223>  n is a, c, g, or t

<400>  4731
gatgaatttc tgtgactgcc agtcagatct taacaggttt ctgttgagcc agaatctgtt       60

tcagatccaa gatggagagg aacactatgg aaacttccca ggtgactttc agagcagttg      120

tttcaaacac atcattgtcc ttttagggga accagttttt agaaggttgt gaattggctt      180

tttcacaaag catgattatc ttcctggctg atccaggaga aaattagaac agaaaaataa      240

tggttgtgga ttttgaaaca aagcaaggta aagccttttt tttttncacc ttgcattggc      300

aaaactacct cttcagtgtt tttaactttt gattcaaaag catcttacca ataaggataa      360

atatcatata catcgttatg aaaatattgc tatgagataa taagccacat atgaatgttg      420

tatacaactt tagggtttac atttaatcct gaagtgttac ctcctttcat gtctatttac      480

actattttcc catttactaa gtggggaggg ggtctcctta tatagtgctt catcgttaat      540

aagtcaatac ctgttgttcc tggg                                             564


<210>  4732
<211>  402
<212>  DNA
<213>  homo sapiens

<400>  4732
tgcagtgctt tgaccccaag gaggaccggt ggagcctgcg gtcaccagca cccttctcac       60

agcggtgtct cgaggctgtc tcccttgagg acaccatcta tgtcatgggg ggtctcatga      120

gcaaaatctt cacctatgat ccaggcacag atgtgtgggg ggaggcagct gtcctcccca      180

gccctgtgga aagctgtgga gtcactgtgt gtgacgggaa ggtccacatc cttggcgggc      240

gggatgatcg cggagaaagc accgataagg tcttcacctt tgaccccagc agtgggcagg      300

tggaggtcca gccatccctg cagcgctgca ccagctccca cggctgtgtc accatcatcc      360

agagcttggg caggtgattc agatttggac agcctgagcc ag                         402


<210>  4733
<211>  468
<212>  DNA
<213>  homo sapiens

<400>  4733
agcctccaaa atgatgctga gtccggacca agcagcagat tcggaccatc ccagctcggc       60

gcactcggat ccggagtccc tgggcggcac ggacaccaag gtgctcggca gcgtgtcgga      120

cctggagccg gtggaggagg ccgagggcga cggcaagggc ggcagccgag ccgcgctcta      180

cccgcacccg cagcagctga gccgcgagga gaagcgccgc cgccggcgcg ccacggccaa      240

gtaccgctcg gcccacgcca cccgcgagcg catccgcgtg gaagccttca acttggcctt      300

cgccgagctc cgcaaattgc tgcccacgct gcccccggac aagaagctct ccaagatcga      360

gatcctgcgc ctggccatct gctacatctc ctatctcaac cacgtcctgg acgtgtaggg      420

cggggtgcgc cgcggggggc cgcctgtccc ggcgtccgcg aaacgcta                   468


<210>  4734
<211>  63
<212>  DNA
<213>  homo sapiens

<400>  4734
ccgagaaacg tgacatgcat gacttctttg tgggacttat gggcaagagg agcgtccagc       60

cag                                                                     63


<210>  4735
<211>  45
<212>  DNA
<213>  homo sapiens

<400>  4735
agctatgtct gggctggtag tcccgccaat gtgagggact tctgt                       45


<210>  4736
<211>  283
<212>  DNA
<213>  homo sapiens

<400>  4736
gaatccaagt gtcctctgat ggtcaaagtt ctagatgctg tccgaggcag tcctgccatc       60

aatgtggccg tgcatgtgtt cagaaaggct gctgatgaca cctgggagcc atttgcctct      120

gggaaaacca gtgagtctgg agagctgcat gggctcacaa ctgaggagga atttgtagaa      180

gggatataca aagtggaaat agacaccaaa tcttactgga aggcacttgg catctcccca      240

ttccatgagc atgcagaggt ggtattcaca gccaacgact ccg                        283


<210>  4737
<211>  397
<212>  DNA
<213>  homo sapiens

<400>  4737
atgcttttta tgactatgcc taatgtaaag aaaatgtatt acattctgta tgtacaaaga       60

ttaaaaatca acctcttttt tgtgctttaa aatgactttg ggattaaaaa agcatatttc      120

ccaatcattg tcttcattcc actacaaagt cacctcacag catcttgctc cactcggcat      180

ctctgtgaaa gcaacatgaa atgaactgta gtaggtgtgt agtttgggga agtcaaatgg      240

ccattttatg tatgtgcatt tggtatcatg ggccgtggaa cagaatatat gttggacctc      300

tgaaaagttg taaggggcca attctaagta ttcttcacgg cagccagaag ttaatggtgg      360

tagcagctga ggtatggttg ttggacgagg ccgattt                               397


<210>  4738
<211>  282
<212>  DNA
<213>  homo sapiens

<400>  4738
gaattcttac tatacctgag tcttttgtaa gctatagttt tatgtacaac cttgtacagt       60

ttttttgaca tacaattcag aactttgttt attctcttgg actttgttct ggccaataca      120

ttttttttaa atctttaaga agaactgtga ttgttttagt gggtattttt ctaattaaat      180

gaaaacttgt ataatggtat tttagagaat gccagtaagt gcatgtttca agttaatgtt      240

tttctcatca cttgtatgtt tctaacacag catgggactt ta                         282


<210>  4739
<211>  484
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (260)..(260)
<223>  n is a, c, g, or t

<400>  4739
attctaagaa aatggacctg acagtaaatg gggaacaact ggatctggat cctggtcaaa       60

ctttaattta ttatgttgat gaaaaagcac ctgaattctc aatgcagggt ctaaaagctg      120

gtgttattgc tgttattgtg gttgtggtga tagcagttgt tgctggaatt gttgtgctgg      180

ttatttccag aaagaagaga atggcaaagt atgagaaggc tgagataaag gagatgggtg      240

agatgcatag ggaactcaan tgcataacta tataatttga agattataga agaagggaaa      300

tagcaaatgg acacaaatta caaatgtgtg tgcgtgggac gaagacatct ttgaaggtca      360

tgagtttgtt agtttaacat catatatttg taatagtgaa acctgtactc aaaatataag      420

cagcttgaaa ctggctttac caatcttgaa atttgaccac aagtgtctta tatatgcaga      480

tcta                                                                   484


<210>  4740
<211>  433
<212>  DNA
<213>  homo sapiens

<400>  4740
ttctgggcat gttcctctct ggcatggtgg ctcaaattga tgctaactgg aacttcctgg       60

attttgccta ccattttaca gtatttgtct tctattttgg agccttttta ttggaagcag      120

cagccacatc cctgcatgat ttgcattgca atacaaccat aaccgggcag ccactcctga      180

gtgataacca gtataacata aacgtagcag cctcaatttt tgcctttatg acgacagctt      240

gttatggttg cagtttgggt ctggctttac gaagatggcg accgtaacac tccttagaaa      300

ctggcagtcg tatgttagtt tcacttgtct actttatatg tctgatcaat ttggatacca      360

ttttgtccag atgcaaaaac attccaaaag taatgtgttt agtagagaga gactctaagc      420

tcaagttctg gtt                                                         433


<210>  4741
<211>  49
<212>  DNA
<213>  homo sapiens

<400>  4741
catctgtccc gctgcgtgtt ttcctcttga tcgggaactc ctgcttctc                   49


<210>  4742
<211>  230
<212>  DNA
<213>  homo sapiens

<400>  4742
gcgcctcggc caaggcttca acggaccaca ccaaaatgcc atctcaaatg gaacacgcca       60

tggaaaccat gatgtttaca tttcacaaat tcgctgggga taaaggctac ttaacaaagg      120

aggacctgag agtactcatg gaaaaggagt tccctggatt tttggaaaat caaaaagacc      180

ctctggctgt ggacaaaata atgaaggacc tggaccagtg tagagatggc                 230


<210>  4743
<211>  438
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (287)..(287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (353)..(353)
<223>  n is a, c, g, or t

<400>  4743
gcgtgtcccg gatcaggaat ggtttcattt ttcttaataa tgtgtgtgtg tgtatgtgtg       60

tgtgtgtgtg tgtgtgtttg tgtgtgtgtg tgtgtgtcct aattaagaga atttttactg      120

gctgcttgtt acatttgttg agggtacaac acactcaaga ataaagtaaa aggatagtca      180

ggatccagat gtttcttttc tagcatttaa tgtgtgtgaa ctcagaacac taccatgaaa      240

gaacacttcc ccccaaaact ggatgcagag gaagaaaaaa aaaaaangaa atggcacagt      300

tttttgtatt ttttttttta gttatttttt gttgttgttg tttgtattgt ttntcttttc      360

tgatagagta tggccacttc tgggggaaaa acatgtaatt aagtaaatgt atacattggt      420

tttcacgttt tacttttg                                                    438


<210>  4744
<211>  90
<212>  DNA
<213>  homo sapiens

<400>  4744
cctgtatgcc aacaacgtca tgtcgggggg caccacgatg taccctggga tcgctgaccg       60

catgcagaaa gagatcaccg cgctggcacc                                        90


<210>  4745
<211>  169
<212>  DNA
<213>  homo sapiens

<400>  4745
aattataaac ttacccattg gatctaaacc atccagatta gatgtcacca acagtgagag       60

cccagaaatt cctttgaatc caattttggc ctttgatgat gaagggacac ttgggcccct      120

gcctcaggta gatggtgttc agacacagca gactgcagaa gttatatga                  169


<210>  4746
<211>  338
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (78)..(78)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (87)..(87)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (92)..(92)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (102)..(103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (105)..(105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (107)..(109)
<223>  n is a, c, g, or t

<400>  4746
gagcgaccct cacatcaagc tacaacttca agcagaagag agaggagttg tgtctatcaa       60

aggagtgtgt gctaaccngt tacctgngct antgaaggaa gnngnannnt tactggcttc      120

taaatgtgtt acggatgagt gtttcttttt tgaacgattg gaatctaata actacaatac      180

ttaccggtca aggaaataca ccagttggta tgtggcactg aaacgaactg ggcagtataa      240

acttggatcc aaaacaggac ctgggcagaa agctatactt tttcttccaa tgtctgctaa      300

gagctgattt taatggccac atctaatctc atttcaca                              338


<210>  4747
<211>  233
<212>  DNA
<213>  homo sapiens

<400>  4747
cacaaacagg cagagaggga cgtgtaggga gagttctttc ctgttttctg tgctttcctt       60

tttacaggac tcccggaagg ccactcatgg ccatgccagg agctttctca gaaacagtca      120

taaacgatct cttgagtctc tttcttgtcc tcccagctga gctttcttat tccacccttt      180

ctggtgtcta taggaatgca tgagagaccc tggacgtttt tctgctctct tct             233


<210>  4748
<211>  272
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (202)..(202)
<223>  n is a, c, g, or t

<400>  4748
gaaatgcctg gcctgcatca aactgggctc tgaggacaaa gttctgggcc ggttggtcca       60

ctgccccata gagacccaag ttctgcggga ggctgaggag caccaggaga cccagtgcct      120

cagggtgcag cgggctggtg aggaccccca cagcttctac ttccctggac agttcgcctt      180

ctccaaggcc ctgccccgca gnctaagcca gcactgagat gcgtggtgcc tccaggaccg      240

ctgcgggggt aaccagtgga agaccccagc cc                                    272


<210>  4749
<211>  169
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (126)..(126)
<223>  n is a, c, g, or t

<400>  4749
gaccgtgtgc ccctttggga ggaagaagac aagccccact agggccaagg gcagcagagc       60

cctgccgagt gagaggctgt ggggcagcgg ctctgtcctg tgccttacca gccctgggga      120

gggggncatt tggctggaag actggaattt aattgccatc gtctttgat                  169


<210>  4750
<211>  277
<212>  DNA
<213>  homo sapiens

<400>  4750
gctatgaagt gacataggcc tcccccacgg tgcctgtgta cggagcctga tgacttcact       60

gggagccttc tggaatcctg cagagggtca aggagcaggg atgttggatg cccacctgtc      120

aagagttcag atcaaagttg cgctgagagc atcacaattt tggttcagcc ttgacgcgtt      180

tgtccaacag ctcattggct ccctttgtat gatatcgtgg tcttctcaca tggtgcccag      240

tcaccaatat ttataatgag gtctaactac agcagta                               277


<210>  4751
<211>  540
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (29)..(29)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (175)..(175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (180)..(180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (182)..(182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (184)..(196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (198)..(198)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (200)..(200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (229)..(231)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (233)..(233)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (295)..(295)
<223>  n is a, c, g, or t

<400>  4751
gcttattatg ttggccctga ggatgcttnc gaagtgaaaa taagaggctg caggatcagc       60

ggcaacagat gctctcccgt ttgcactaca gctttcacgg acaccattcc aaaaaggggc      120

aggttgcaaa gttagacttg gaatgcatgg tgccggtcag tgggcacgag aactnctgtn      180

tnannnnnnn nnnnnnanan gagacaagca gacctcagca acgataagnn ncntctcgct      240

tgttcactgg ggcatgtaca gtgggcacgg gaagctggaa ttcgtatgac ggagncttat      300

ctgaactaca cttactgaac agcttgaagg ccttttgagt tctgctggac aggagcactt      360

tatctgaaga caaactcatt taatcatctt tgagagacaa aatgacctct gcaaacagaa      420

tcttggatat ttcttctgaa ggattatttg cacagactta aatacagtta aatgtgttat      480

ttgcttttaa aattataaaa agcaaagaga agactttgta cacactgtca ccagggttat      540


<210>  4752
<211>  503
<212>  DNA
<213>  homo sapiens

<400>  4752
aaggcagctg atccaggcaa tcgttctgct ggccaagaag ttaaactatt ttgagcatta       60

gaatggagga aatccggtca gccaagtgca gagttcagac ttcgctaagg gcttgttttt      120

cttcagcatt tacttgaaga ttaatgtagg atgacaggct ctcctggctg tcctaccatc      180

agctctgcct tgcactgtgg tcgtcaactt tcctcaaatc aaaaacaggc aggtacaggt      240

agtgggctca caacgtttga cctcgactgg tttttctaag ttattttgta catttttcag      300

cagcaaaacc aaactgggtc ttcagcttta tccccgtttc ttgcaaggga agagccttta      360

tacaattgga cgcattttgg tttttcctca ttgagaattc aaatcctctt ttgtattgtt      420

tctacaataa tttgtaaaca tatttatttt tacctgcttt tttttttttt tttaattttc      480

aggtcaagtt ttttatactg cac                                              503


<210>  4753
<211>  35
<212>  DNA
<213>  homo sapiens

<400>  4753
gatgagatgg ttgttgccct agtctgttgg tagaa                                  35


<210>  4754
<211>  239
<212>  DNA
<213>  homo sapiens

<400>  4754
aatgggtaag aagtctactc caaacctagg tctctatgtc agaccagacc taggtgcttc       60

tctaggaggg aaacagggag acctggggtc ctgtggataa ctgagtgggg agtctgccag      120

gggagggcac cttcccattg tgccttctgt gtgtattgtg cattaacctc ttcctcacca      180

ctaggcttct ggggctgggt cccacatgcc cttgaccctg acaataaagt tctctattt       239


<210>  4755
<211>  378
<212>  DNA
<213>  homo sapiens

<400>  4755
cagtttggct ttgggccttt tgagttgcct cctcagtggc tctcagagac ccgaaacagc       60

aagaagcggc tgcttccccc cttgggcaac accccagaag agctgatcca gacaaaggtg      120

cccaaggtag gcagggtgga gcggaagatg agcagaaaca ataaagtgag catttttcca      180

aaggtggatt cctagcaagg attgtaaatt cttggaagca acggggagct tccatattcc      240

caccagagtg tgggaatgct gtggccatgt gattgtatga tctccttgca actcagtgtg      300

agttgattcc tccaatatgg gccagatgct tttgaatgat agggaaatct acataaaatc      360

cagtgtcctc tttattga                                                    378


<210>  4756
<211>  431
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (82)..(82)
<223>  n is a, c, g, or t

<400>  4756
ttcagaaagc acagtccacg cgcaagaaca aagtccaagc gccacagcct caaacgtggc       60

caccagtcac tccacggaga anagtggatg gagacacaca gacaacagtt gagaaagatg      120

gtttgtcaac agtgaccctg gttggaatca tagttggggt cttactagcc atcggcttca      180

ttggtggaat catcgttgtg gttatgcgaa aaatgtcggg aagggtactc gcccctaaag      240

agctgaaggg ttacgccctg ctgccaacgt gcttaaaaaa agaccgtttc tgactctgtg      300

ccctgtccct gagctcgtgg gagaagatga cccgtggaac acttgcctgg cccactcaga      360

atccacggtg acctctccgc ttgccaaaat aaccgaagga aagaccgttc accagacttg      420

gctcctctaa a                                                           431


<210>  4757
<211>  221
<212>  DNA
<213>  homo sapiens

<400>  4757
tgtctgccct ctttggcatc ccgatggcac tcatctgggg catttacttc gccattctct       60

ctttcctgca catctgggca gttgtaccat gcattaagag cttcctgatt gagattcagt      120

gcatcagccg tgtctattcc atctacgtcc acaccgtctg tgacccactc tttgaagctg      180

ttgggaaaat attcagcaat gtccgcatca acttgcagaa a                          221


<210>  4758
<211>  36
<212>  DNA
<213>  homo sapiens

<400>  4758
cttgggaact ctagtctcgc ctcgggttgc aatgga                                 36


<210>  4759
<211>  526
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (43)..(43)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (45)..(45)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (51)..(51)
<223>  n is a, c, g, or t

<400>  4759
gactcacaag ccttcaatcc tgataatcct tatcatcagc agnangggga naagcatgac       60

attcgaccct agactggatc acgaaggaat ctgttgtata gaatgtaggc ggagctacac      120

ccactgccag aagatctgtg aacccctggg gggctattac ccatggcctt ataattatca      180

aggctgccgt tcggcctgca gagtcatcat gccatgtagc tggtgggtgg cccgtatctt      240

gggcatggtg tgaaatcact tcatatatca tgtgctgtaa aataagaact agctgaagag      300

acaaccaaag aagcattaag gcaggttgat gctgatggga ccataaaata tttttacact      360

caacctgagc ggttattctt gacactctta acagaatttt ttcaattgtt ttccagaact      420

ttagtatatg caaatgtact gaaagggtag ttcaagtcta aaatgccata acccctttat      480

tatttgttat tttttatttg cattgctttg ccataagtct tccctt                     526


<210>  4760
<211>  511
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (374)..(374)
<223>  n is a, c, g, or t

<400>  4760
ggtttcgggt tgctctgaag acttttgaat taaatggata ccagattccc aagggctgga       60

atgttatcta cagtatctgt gatactcatg atgtggcaga gatcttcacc aacaaggaag      120

aatttaatcc tgaccgattc atgctgcctc acccagagga tgcatccagg ttcagcttca      180

ttccatttgg aggaggcctt aggagctgtg taggcaaaga atttgcaaaa attcttctca      240

aaatatttac agtggagctg gccaggcatt gtgactggca gcttctaaat ggacctccta      300

caatgaaaac cagtcccacc gtgtatcctg tggacaatct ccctgcaaga ttcacccatt      360

tccatgggga aatntgatga gcttgaatgt tcaaacctga gacttattgg aagtgtacat      420

atgagttttt aaggagtgtt gtgttgactt tatatttaat ttctaaatgt atattataat      480

atttatgtgt tttgactata ctaccacaat c                                     511


<210>  4761
<211>  306
<212>  DNA
<213>  homo sapiens

<400>  4761
acgatgatgc cgcagaacag gaggaatatg atgaagaaga gcaagaagag gaaaatgact       60

acattaattc atactttgaa gatggagatg attttggcgc agacagtgat gacaacatgg      120

atgaggcaac ctattaggca tgaaattttt caaaaaatat ttttatgatg cagcttctga      180

acatttggac agacttgatt tgtattttat ttctgataag gaataagtac ttgtttctgt      240

tgttttggac aaatagttgt taccaaaata ttcaaaacca ctttgagttt acatactagt      300

tacctt                                                                 306


<210>  4762
<211>  296
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (109)..(109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (202)..(202)
<223>  n is a, c, g, or t

<400>  4762
aaacaaacac atgcgagtcc actctggaga cagaccatac cagtgtgtgt attgtactaa       60

gaggttcaca gcctccagca tactccgcac acacatcagg cagcactcng gggagaagcc      120

cttcaaatgc aagtactgtg gtaaatcttt tgcatcccat gctgcccatg acagccatgt      180

ccggcgttca cacaaggagg angatggctg ctcatgcagc atctgtggga aaatcttctc      240

agatcaagaa acattctact cccacatgaa gtttcatgaa gactactagc cctgcc          296


<210>  4763
<211>  524
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (313)..(313)
<223>  n is a, c, g, or t

<400>  4763
atctctcttc tagtcatgct gtgcatgccg cttactctgt tggggtctat ataaatttgt       60

tgaactctta cctacattcc aaagaagttt caaggaacca taaatatatg tatacatata      120

catatataaa atatatatat taaaataaaa ttatcaggaa tactgcctca gttattgaac      180

tttttttttt aagaatactt tttttttaag ctgagaagta tagggatgaa aaagatgtta      240

tattgtgttt gactattttc caacttgtat tttcatataa tttatatttt ttaaaagctg      300

aaaatttaga agnaagatga aaaaaaggaa aagcaggtgc tttttaaaaa tcagaactga      360

ggtagcttag agatgtagcg atgtaagtgt cgatgttttt ttaaaaaaaa atgcaaaaaa      420

attcttatgg cggagttttt tgtttgttta ttttagtagc tgatgctggc acatcatttt      480

gctggagagt tttttatata ctgtagcctg atttcatatt gtat                       524


<210>  4764
<211>  147
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (72)..(72)
<223>  n is a, c, g, or t

<400>  4764
gaccgcctcc tggatctccc cgccgcagcc tcctcagaag acatcgagcg gtcctgagag       60

cctcctgggc angtttgtct gtgtgctgta acctgaagtc aaaccttaag ataatggata      120

atcttcggcc aatttatgca gagtcag                                          147


<210>  4765
<211>  515
<212>  DNA
<213>  homo sapiens

<400>  4765
gcataggact atagtcagca tgctagactg agaggtaaac actgatgcaa ttagaacagg       60

tactgatgct gtcagtgttt aacactatgt ttagctgtgt ttatgctata aaagtgcaat      120

attagacact agctagtact gctgcctcat gtaactccaa agaaaacagg atttcattaa      180

gtgcattgaa tgtggatatt tctctaagtt actcatattg tcctttgctt gaatgcaatg      240

ccgtgcagat ttatgaggct gctattttta ttttctgtgc attactttaa caccttaaag      300

ggagaagcaa acatttcctt cttcagctga ctggcaatgg ccctttaact gcaataggaa      360

gaaaaaaaaa aaaggtttgt gtgaaaattg gtgataactg gcacttaaga tcgaaaagaa      420

atttctgtat acttgatgcc ttaagatgcc caaagctgcc caaagctctg aaagacttta      480

agataggcag taatgcttac tacaatacta ctgag                                 515


<210>  4766
<211>  402
<212>  DNA
<213>  homo sapiens

<400>  4766
gcttgtgcct ggcatcccca agggagaagg tgccaggtca gcaggagcag cagcagggat       60

gtatagaaag aaccacagct ggcctctaaa ggatggcact gaggcaccgg agatcttgag      120

gcactggaga tcactgaggg gctggcctgt cccctgcaag gagtgtggga ccaggtgggg      180

caaggctggg agatgcaggc tctgtttgca gattatggcc cagagtctct gcttgtgggt      240

gcttgatcca cctgctggga ccctgcagtc ctcggccagc ctggctgtca gttggggatt      300

ccacctttct gctgagcgtc ttctcggagc tggaggccca tcttcagtga gagatcacaa      360

agcggccagg caggtgggag actgaatttg ccttgttcga ga                         402


<210>  4767
<211>  438
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (378)..(378)
<223>  n is a, c, g, or t

<400>  4767
gaaaccctcg tgcaggcccg aaagagaaag cgaaccagta tcgagaaccg agtgagaggc       60

aacctggaga atttgttcct gcagtgcccg aaacccacac tgcagcagat cagccacatc      120

gcccagcagc ttgggctcga gaaggatgtg gtccgagtgt ggttctgtaa ccggcgccag      180

aagggcaagc gatcaagcag cgactatgca caacgagagg attttgaggc tgctgggtct      240

cctttctcag ggggaccagt gtcctttcct ctggccccag ggccccattt tggtacccca      300

ggctatggga gccctcactt cactgcactg tactcctcgg tccctttccc tgagggggaa      360

gcctttcccc ctgtctcngt caccactctg ggctctccca tgcattcaaa ctgaggtgcc      420

tgcccttcta ggaatggg                                                    438


<210>  4768
<211>  402
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (184)..(184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (250)..(250)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (331)..(331)
<223>  n is a, c, g, or t

<400>  4768
cataggcgcc tagtgtagcc atcgagggac ttgacttgtg tgtgtttctg aagtgttcga       60

gggtaccagg agagctggcg atgactgaac tgctgatgga caaatgctct gtgctctcta      120

gtgagccctg aatttgcttc ctctgacaag ttacctcacc taatttttgc ttctcaggaa      180

tganaatctt tggccactgg agagcccttg ctcagttttc tctattctta ttattcactg      240

cactatattn taagcactta catgtggaga tactgtaacc tgagggcaga aagcccaatg      300

tgtcattgtt tacttgtcct gtcactggat ntgggctaaa gtcctccacc accactctgg      360

acctaagacc tggggttaag tgtgggttgt gcatccccaa tc                         402


<210>  4769
<211>  345
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (34)..(35)
<223>  n is a, c, g, or t

<400>  4769
gtatattgtg ctagcttgtc taagaataaa cttnnatact gttgggggag ggctgcacct       60

gtcaagataa cctgtcaatg tagtaggaaa acaggagggg acagtaacag aaaagcacgg      120

gaaaagatgg caaggttagt taaaatagaa aagtgctcag ttcctcatac ctgtaatccc      180

agcagtttag ggggccaagg caggtgggtc acttgagccc aagagttcaa ggccatcctg      240

ggcaatgtgg cgaaagtgtc tacaaaaaaa tacaaaaaga ggaagaaatg atatttcaca      300

agtttgtatc atttgtcatg atgtgactcg aatatattaa atctt                      345


<210>  4770
<211>  327
<212>  DNA
<213>  homo sapiens

<400>  4770
gacttcttgt tcatgttttg ctaatgctcg tatctccttg attacataat gttagtagca       60

ctgagacccc catggtaatg taacttaatt ataagctatg tcactaccct cctgtaaaat      120

actattggac agacacagag ggacccttgg ctcctgtgtc tggtccacac accacagaag      180

cttgtattat cagtgaatat aaatgtacta catttgcatg ccttttgggt ttgccttaat      240

tcttacctca tttgcatcct atcgatctgg aaagagctgt tttggatgaa tgcagtataa      300

aatgtaaaaa ccctgctaaa tgactta                                          327


<210>  4771
<211>  326
<212>  DNA
<213>  homo sapiens

<400>  4771
gctccgggat tatcgaaagg gtcaccggat tgcctgccac aggttttgga gctgtctttc       60

ctagacatcc accggattgg agcaaaatgt gtgcattgac aacgtactca gaagattatg      120

ttccaccata tgattatcag ccacatgctt atccctgtca agatgattat tccatagtcc      180

acagaaaatg ccgttctcag ttcacggatc taaatggttc taaaagattt ggcatcaaca      240

cttggcatga tgagagtggg atttatgcta attcagatgt aaaacagaaa ctctatccct      300

tgactagtgg gcctattgtg ccaatt                                           326


<210>  4772
<211>  331
<212>  DNA
<213>  homo sapiens

<400>  4772
agtgcccctt cctgttgaca agttggcacc tttacctctg gacaacattc ttccctttat       60

ggatccatta aagcttcttc tgaaaactct gggcatttct gttgagcacc ttgtggaggg      120

gctaaggaag tgtgtaaatg agctgggacc agaggcttct gaagctgtga agaaactgct      180

ggaggcgcta tcacacttgg tgtgacatca agataaagag cggaggtgga tggggatgga      240

agatgatgct cctatcctcc ctgcctgaaa cctgttctac caattataga tcaaatgccc      300

taaaatgtag tgacccgtga aaaggacaaa t                                     331


<210>  4773
<211>  504
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (410)..(410)
<223>  n is a, c, g, or t

<400>  4773
tgctcagttc ctccaggaca tgagaagata tatgccacca gctcacagga acttcctgtg       60

ctcattagag tcaaatccct cagtccgtga gtttgtcctt tcaaaaggtg atgctggcct      120

gcgggaagct tatgacgcct gtgtgaaagc tctggtctcc ctgaggagct accatctgca      180

aatcgtgact aagtacatcc tgattcctgc aagccagcag ccaaaggaga ataagacctc      240

tgaagaccct tcaaaactgg aagccaaagg aactggaggc actgatttaa tgaatttcct      300

gaagactgta agaagtacaa ctgagaaatc ccttttgaag gaaggttaat gtaacccaac      360

aagagcacat tttatcatag cagagacatc tgtatgcatt cctgtcattn acccattgta      420

acagagccac aaactaatac tatgcaatgt tttaccaata atgcaataca aaagacctca      480

aaatacctgt gcatttcttg tagg                                             504


<210>  4774
<211>  264
<212>  DNA
<213>  homo sapiens

<400>  4774
acgctcggcc tgaagtgact cgtaacgacg ttgcaccaac cctcatgagt gtcccccggt       60

atcttccccg ccctgccaat cccgatgaaa ttggaaattt tattgatgaa aatctgaaag      120

cggctgatac tgaccccaca gccccgcctt atgattctct gctcgtgttt gactatgaag      180

gaagcggttc cgaagctgct agtctgagct ccctgaactc ctcagagtca gacaaagacc      240

aggactatga ctacttgaac gaat                                             264


<210>  4775
<211>  471
<212>  DNA
<213>  homo sapiens

<400>  4775
tgagaaactc acagcctgga ccaagccaga ctgtatgaag agtactgagg ttgaagttct       60

ccttccaaaa tttaaactac aagaggatta tgacatggaa tctgtgcttc ggcatttggg      120

aattgttgat gccttccaac agggcaaggc tgacttgtcg gcaatgtcag cggagagaga      180

cctgtgtctg tccaagttcg tgcacaagag ttttgtggag gtgaatgaag aaggcaccga      240

ggcagcggca gcgtcgagct gctttgtagt tgcagagtgc tgcatggaat ctggccccag      300

gttctgtgct gaccaccctt tccttttctt catcaggcac aacagagcca acagcattct      360

gttctgtggc aggttctcat cgccataaag ggtgcactta ccgtgcactc ggccatttcc      420

ctcttcctgt gtccccagat ccccactaca gctccaagag gatgggccta g               471


<210>  4776
<211>  353
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (36)..(36)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (129)..(129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (160)..(160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (193)..(193)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (203)..(203)
<223>  n is a, c, g, or t

<400>  4776
ttgaggctct gcagcttagc ttcaagaaca tgtgtnagct gcggcccttg ctgcagaagt       60

gggtggagga agctgacaac aatgaaaatc ttcaggagat atgcaaagca gaaaccctcg      120

tgcaggccng aaagagaaag cgaaccagta tcgagaaccn agtgagaggc aacctggaga      180

atttgttcct gcngtgcccg aancccacac tgcagcagat cagccacatc gcccagcagc      240

ttgggctgga gaaggatgtg gtccgagtgt ggttctgtaa ccggcgccag aagggcaagc      300

gatcaagcag tggctatgca caacgagagg attttgaggc tgttgggtct cct             353


<210>  4777
<211>  352
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (248)..(248)
<223>  n is a, c, g, or t

<400>  4777
gatgcctggt gaacccgact gggaaccttc caatgtggag caaccagacc tggaacaatt       60

caacctggag caaccagacc cagaacatcc agtcctggag caaccactcc tggaacactc      120

agacctggtg cacccaatcc tggaacaatc aggcctggaa cagtcccttc tataactgtg      180

gagaggaatc tctgcagtcc tgcatgcagt tccagccaaa ttctcctgcc agtgacttgg      240

aggctgcntt ggaagctgct ggggaaggcc ttaatgtaat acagcagacc actaggtatt      300

ttagtactcc acaaaccatg gatttattcc taaactactc catgaacatg ca              352


<210>  4778
<211>  232
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (109)..(109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (172)..(172)
<223>  n is a, c, g, or t

<400>  4778
tgatcgtgtg cggaacctgc aaagtgaggt ggagggagtt aagaatatta tgacccagaa       60

tgtggagcgg atcctggccc ggggggaaaa cttggaacat ctccgcaana agacagagga      120

tctggaagcc acatctgagc acttcaagac gacatcgcag aaggtggctc gnaaattctg      180

gtggaagaac gtgaagatga ttgtccttat ctgcgtgatt gtttttatca tc              232


<210>  4779
<211>  459
<212>  DNA
<213>  homo sapiens

<400>  4779
tcactgtcct ttctatgtca gcattcagag ttactggctg tcatttttca tggtgatgat       60

tttatttgta gctttcataa cctgttggga agaagttact actttggtac aggctatcag      120

gataacttcc tatatgaatg aaactatctt atattttcct ttttcatccc actccagtta      180

tactgtgaga tctaaaaaaa tattcttatc caagctcatt gtctgttttc tcagtacctg      240

gttaccattt gtactacttc aggtaatcat tgttttactt aaagttcaga ttccagcata      300

tattgagatg aatattccct ggttatactt tgtcaatagt tttctcattg ctacagtgta      360

ttggtttaat tgtcacaagc ttaatttaaa agacattgga ttacctttgg atccatttgt      420

caactggaag tgctgcttca ttccacttac aattcctaa                             459


<210>  4780
<211>  243
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (168)..(168)
<223>  n is a, c, g, or t

<400>  4780
aataggtata tatttagtgg ccatttatta tcaatggtaa cacaatggag tactaagatg       60

gtatttgcac atttaagata tgttacttta ccaattttta atggtaatca actctgctac      120

tggcatgatg aaatagtaca taactggtca ttaattatga acatttantt ctccagtgcg      180

tttttatgaa gatctggttg aaaattgtat ttctatgtaa actcaacgat atgtttggtt      240

ttc                                                                    243


<210>  4781
<211>  367
<212>  DNA
<213>  homo sapiens

<400>  4781
tctggacgcg ctgggtggat gcggggggct cctgggaact gtgttggagc cgagcaagcg       60

ctagccaggc gcaagcgcgc acagactgta gccatccgag gacacccccg cccccccggc      120

ccacccggag acacccgcgc agaatcgcct ccggatcccc tgcagtcggc gggagtgttg      180

gaggtcggcg ccggcccccg ccttccgcgc cccccacggg aaggaagcac ccccggtatt      240

aaaacgaacg gggcggaaag aagccctcag tcgccggccg ggaggcgagc cgatgccgag      300

ctgctccacg tccaccatgc cgggcatgat ctgcaagaac ccagacctcg agtttgactc      360

gctacag                                                                367


<210>  4782
<211>  218
<212>  DNA
<213>  homo sapiens

<400>  4782
ctgatggaaa gttaagcgtg aaatttgggg tcctcttccg tgatgataaa tgtgccaacc       60

tctttgaagc attggtagga actcttaaag ctgcaaaacg aaggaagatt gtaacatatc      120

caggagagct gcttctgcaa ggtgttcatg atgatgttga cattatatta ctgcaagatt      180

aatgtggttt acatatcttt atgtactgcc attttttg                              218


<210>  4783
<211>  290
<212>  DNA
<213>  homo sapiens

<400>  4783
gggcaccaat aacaaggagc tcaccctgcc cgctcccaac ccccctcctg ctcctccctg       60

ccccccaagg ttctggttcc atttttcctc tgttcacaaa ctacctctgg acagttgtgt      120

tgttttttgt tcaatgttcc attcttcgac atccgtcatt gctgctgcta ccagcgccaa      180

atgttcatcc tcattgcctc ctgttctgcc cacgatcccc tcccccaaga tactctttgt      240

ggggaagagg ggctggggca tggcaggctg ggtgaccgac taccccagtc                 290


<210>  4784
<211>  110
<212>  DNA
<213>  homo sapiens

<400>  4784
tctcctccct gggctaagca ggggagaagc gggctggggg tagcctggat gtgggccaag       60

tccactgtcc tccttggcgg caaaagccca ttgaagaaga accagcccag                 110


<210>  4785
<211>  166
<212>  DNA
<213>  homo sapiens

<400>  4785
tttatgtatg ttacccttca gtaagttctc cccattttag ttttctagga ctgaaaggat       60

tcttttctac attatacatg tgtgttgtca tatttggctt ttgctatata ctttaacttc      120

attgttaaat ttttgtattg tatagtttct ttggtgtatc ttaaaa                     166


<210>  4786
<211>  400
<212>  DNA
<213>  homo sapiens

<400>  4786
ggcatccgtt gcagttgatc cacaaccgag tgtggtgact cgggtggtca acctgccctt       60

ggtgagctcc acgtatgacc tcatgtcctc agcctatctc agtacaaagg accagtatcc      120

ctacctgaag tctgtgtgtg agatggcaga gaacggtgtg aagaccatca cctccgtggc      180

catgaccagt gctctgccca tcatccagaa gctagagccg caaattgcag ttgccaatac      240

ctatgcctgt aaggggctag acaggattga ggagagactg cctattctga atcagccatc      300

aactcagatt gttgccaatg ccaaaggcgc tgtgactggg gcaaaagatg ctgtgacgac      360

tactgtgact ggggccaagg attctgtggc cagcacgatc                            400


<210>  4787
<211>  230
<212>  DNA
<213>  homo sapiens

<400>  4787
agatggacat ttaaagcacc agccatcgtg tggagcacta ccaaggggcc cctcagggcc       60

ttcctgggag gagtcccacc agccaggcct tatgaaagtg atcatactgg gcaggcgttg      120

gcgtggggtc ggacacccca gccctttctc cctcactcag ggcacctgcc ccctcctctt      180

cgtgaacacc agcagatacc tccttgtgcc tccactgatg caggagctgc                 230


<210>  4788
<211>  196
<212>  DNA
<213>  homo sapiens

<400>  4788
caagaacggg caggttatcg gcattggagc aggacagcag tctcgtatac actgcactcg       60

ccttgcagga gataaggcaa actattggtg gcttagacac catccacaag tgctttcgat      120

gaagtttaaa acaggagtga agagagcaga aatctccaat gccatcgatc aatatgtgac      180

tggaaccatt ggcgag                                                      196


<210>  4789
<211>  151
<212>  DNA
<213>  homo sapiens

<400>  4789
gagtatgcag aggagttttc aagaggctat ctggtgtgat attgtaatag gctgaatgca       60

aaagcagata caagattcca gctttcgtct gtcatcagac attgaagaga tttggagaaa      120

tgtaaagcag cagtactctt ctcactaatt t                                     151


<210>  4790
<211>  39
<212>  DNA
<213>  homo sapiens

<400>  4790
aatacctgga ctttaattgc acccatgaat gtggctagg                              39


<210>  4791
<211>  413
<212>  DNA
<213>  homo sapiens

<400>  4791
aagcctcagt tatataaccc acgaaaaaac agagcctcct agatgtaaca ttcctgatca       60

aggtacaatt ctttaaaatt cactaatgat tgaggtccat atttagtggt actctgaaat      120

tggtcacttt cctattacac ggagtgtgcc taaaactaaa aagcattttg aaacatacag      180

aatgttctat tgtcattggg aaatttttct ttctaaccca gtggaggtta gaaagaagtt      240

atattctggt agcaaattaa ctttacatcc tttttcctac ttgttatggt tgtttggacc      300

gataagtgtg cttaatcctg aggcaaagta gtgaatatgt tttatatgtt atgaagaaaa      360

gaattgttgt aagtttttga ttctactctt atatgctgga ctgcattcac aca             413


<210>  4792
<211>  281
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (155)..(155)
<223>  n is a, c, g, or t

<400>  4792
ctttcttaga ttttaggtag gaggggagca gaggaattat gaactggggt aaacccattt       60

tgaatattag cattgccaat atcctgtatt cttgttttac atttggatta gaaatttaac      120

atagtaattc ttaagtcttt tgtctgattt ttaanagtac tttcttataa atttggatca      180

tgttatgatt tgtaacattc acacaacacc tcacttttga atctataaaa gaattgcacg      240

tatgagaaac ctatatttca atactgctga aacagacatg a                          281


<210>  4793
<211>  324
<212>  DNA
<213>  homo sapiens

<400>  4793
tttttcaccc ctggcattag cagcttcgac ctcattttcc agatgcacca gctcctatta       60

ataagttagc aaggaaagtg tatgtcacgt gcaggaacag tgaggcaggg acaggggttc      120

tgctccttct cacttcacca ccggcacaca gcttgcccct gtctttgccc ccaaaggtat      180

tttgtgtcta gtgtcaaatt ggagctattc ttcactggtc cttaaccttg ggttttaaaa      240

agaaggcttc tctgtttggg tagcgtaaga gctgagtata gtaagtcctc ttccaaagag      300

atggcaatat gctgggcatc tact                                             324


<210>  4794
<211>  528
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (294)..(294)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (300)..(300)
<223>  n is a, c, g, or t

<400>  4794
aagccgcacg tggagatccg ccaggacggg gatcagttct acatcaagac atccaccacg       60

gtgcgcacca ctgagatcaa cttcaaggtc ggagaaggct ttgaggagga gaccgtggac      120

ggacgcaagt gcaggagttt agccacttgg gagaatgaga acaagatcca ctgcacgcaa      180

actcttcttg aaggggacgg ccccaaaacc tactggaccc gtgagctggc caacgatgaa      240

cttatcctga cgtttggcgc cgatgacgtg gtctgcacca gaatttatgt ccgnaggagn      300

tgaaggcagc tggcttgctc ctactttcag gaagggatgc aggctcccct gaggaatatg      360

tcatagttct gagctgccag tggaccgccc ttttccccta ccaatattag gtgatcccgt      420

tttccccatg acaatgttgt agtgtccccc acccccaccc cccaggcctt ggtgcctctt      480

gtatccctag tgctccatag tttggcattt gcacggtttc gaagtcat                   528


<210>  4795
<211>  186
<212>  DNA
<213>  homo sapiens

<400>  4795
actacatgta cattgaggcc tcccatatgg tgtatggaca aaaagcacgc ctcttgtcca       60

ggcctctgcg aggagtctct ggaaaacact gcttgacctt tttctaccac atgtatggag      120

ggggcactgg cctgctgagt gtttatctga aaaaggaaga agacagtgaa gagtccctct      180

tatgga                                                                 186


<210>  4796
<211>  159
<212>  DNA
<213>  homo sapiens

<400>  4796
cctgaatttg ccacagtcaa gtcaacgttc ccaccccact ggcttggtta cagggctctc       60

acatggggta ggggagccat actcccaccc ccttgcgtat tcccctgggt ttgttgatat      120

tttgcactct taacacctgc caataaagac ggtctacac                             159


<210>  4797
<211>  508
<212>  DNA
<213>  homo sapiens

<400>  4797
gactactttc tatgcaagac tgagatatgg aatagatagg aagagatatg tactgctggg       60

tacatggaca gtaagtgtgt tttcagatgg agtaccagca ccgaaaatgg gttgagggag      120

gatgggttgt atgtatgttt ctgcccacta attttgagca gccatattat gaattaaatc      180

gtcacagcca agtaataacc caagaatggt atgagtttca tgtgtaatag ctcaaatgga      240

ataagcatga atgctggagt ggaccattat cctcaaatat tctatgtcac ttctcattta      300

aagactcttg ttatgaacta ttagaaactt taggcaaaat caaaagtatt tgcggcaaaa      360

taaaggccta ttctactctt atttaaagtg aaacactgta tacttgtttc tctccaaagc      420

gaaattaagt atttataatt tcaattgcct cgataagttt ccaagtcact gaaatctgct      480

gaaggtttta ctgtattgtt gcacaact                                         508


<210>  4798
<211>  286
<212>  DNA
<213>  homo sapiens

<400>  4798
cccctgagcg taaatactct gtctggattg ggggctccat cctggcctct ctgtccacct       60

tccagcaaat gtggattagc aagcaagagt acgatgaggc aggcccatcc attgtcccca      120

ccgcaaaatg cttctaagat gccttctctc tccatctacc ttccagtcag gatgacggta      180

ttatgcttct tggagtcttc caaaccacct tccctcatct ttcatcaatc attgtacagt      240

ttgtttacac acgtgcaatt tgtttgtgct tctaatattt attgct                     286


<210>  4799
<211>  436
<212>  DNA
<213>  homo sapiens

<400>  4799
atggatgtct agaaaacacc cctgacactg cagagttcag tcgagagttc cagttgcacc       60

agcatctctt tgatccggaa catgactatc caggcttggg caagtggaac aagaaactcc      120

tttacgagaa gatgaaggga ggagagagac gaaagcggag gagtgtcaat ccatatctac      180

aaggacagag actggataat gttgttgcaa agaagtctgt cccccatttt tcagatgagg      240

ataagggatt ccagagtaaa gagaagatgc tagacgaaaa cccacattac ctgttaggcc      300

tcagcatggc ttatgtgcac gtgtaaatgg agtccctgtg aatgacagca tgtttcttac      360

atagataatt atggatacaa agcagctgta tgtagatagt gtattgtctt cacaccgatg      420

attctgcttt ttgcta                                                      436


<210>  4800
<211>  465
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (272)..(272)
<223>  n is a, c, g, or t

<400>  4800
gtcatcattt tagctgtggt tgtggttggc ttttcatgtc ggaagaaatt catttcttac       60

ctcaaaggca tctgctcagg tggtggagga ggtcccgaac gtgtgcacag agtccttttc      120

cggcggcgtt catgtccttc acgagttcct ggggcggagg acaatgcccg caacgagacc      180

ctgagtaaca gatacttgca gcccacccag gtctctgagc aggaaatcca aggtcaggag      240

ctggcagagc taacaggtgt gactgtagag tngccagagg agccacagcg tctgctggaa      300

caggcagaag ctgaagggtg tcagaggagg aggctgctgg ttccagtgaa tgacgctgac      360

tccgctgaca tcagcacctt gctggatgcc tcggcaacac tggaagaagg acatgcaaag      420

gaaacaattc aggaccaact ggtgggctcc gaaaagctct tttat                      465


<210>  4801
<211>  236
<212>  DNA
<213>  homo sapiens

<400>  4801
tgatattgat gcatttgacc ctacactggc tccagccaca ggaactcctg ttgtcggggg       60

actaacctat cgagaaggca tgtatattgc tgaggaaata cacaatacag ggttgctatc      120

agcactggat cttgttgaag tcaatcctca gttggccacc tcagaggaag aggcgaagac      180

tacagctaac ctggcagtag atgtgattgc ttcaagcttt ggtcagacaa gagaag          236


<210>  4802
<211>  286
<212>  DNA
<213>  homo sapiens

<400>  4802
tattttgtag cttcctcact ggtttgtgtt gctaagcaaa cgtatacaaa cagaaaaaga       60

gcttcctaaa ttgcacattt ttgcacctct tgtgcattct gcaagaagac aatgaatcca      120

tgtatttcta tataagtatc ttcttcattt ttaacctgtt ttcatttgta atgatgctac      180

ataattttgt ggctccctaa tgcaataatg tacagaagat aaaaaaattt ataattgaac      240

aatttgtctt tctgttcgct gaatatattg caggtcatgc tcccat                     286


<210>  4803
<211>  416
<212>  DNA
<213>  homo sapiens

<400>  4803
gtcatcatgg cttcagcgtc tgctcgtgga aaccaagata aagatgccca ttttccacca       60

ccaagcaagc agagcctgtt gttttgtcca aaatcaaaac tgcacatcca cagagcagag      120

atctcaaaga ttatgcgaga atgtcaggaa gaaagtttct ggaagagagc tctgcctttt      180

tctcttgtaa gcatgcttgt cacccaggga ctagtctacc aaggttattt ggcagctaat      240

tctagatttg gatcattgcc caaagttgca cttgctggtc tcttgggatt tggccttgga      300

aaggtatcat acataggagt atgccagagt aaattccatt tttttgaaga tcagctccgt      360

ggggctggtt ttggtccaca gcataacagg cactgcctcc ttacctgtga ggaatg          416


<210>  4804
<211>  472
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (37)..(37)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (439)..(442)
<223>  n is a, c, g, or t

<400>  4804
ctatgtggac ttcagcgatg tgggctggaa tgactgnatt gtggccccac caggctacca       60

ggccttctac tgccatgggg actgcccctt tccactggct gaccacctca actcaaccaa      120

ccatgccatt gtgcagaccc tggtcaattc tgtcaattcc agtatcccca aagcctgttg      180

tgtgcccact gaactgagtg ccatctccat gctgtacctg gatgagtatg ataaggtggt      240

actgaaaaat tatcaggaga tggtagtaga gggatgtggg tgccgctgag atcaggcagt      300

ccttgaggat agacagatat acacaccaca cacacacacc acatacacca cacacacacg      360

ttcccatcca ctcacccaca cactacacag actgcttcct tatagctgga cttttattta      420

aaaaaaaaaa aaaaaaaann nnggaaaaaa tccctaaaca ttcaccttga cc              472


<210>  4805
<211>  380
<212>  DNA
<213>  homo sapiens

<400>  4805
gagagcctgt gagattccta cctttgttct gctacccact gccagatgct gcaagcgagg       60

tccaagcaca tcttgtcaac atgcattgcc atgaatttct accagatgtg cttttattta      120

gctttacata ttcctttgac caaatagttt gtgggttaaa caaaatgaaa atatcttcac      180

ctctattctt gggaaacacc ctttagtgta catttatgtt cctttattta ggaaacacca      240

ttataaaaac acttatagta aatggggaca ttcactataa tgatctaaga agctacagat      300

tgtcatagtt gttttcctgc tttacaaaat tgctccagat ctggaatgcc agtttgacct      360

ttgtcttcta taatatttcc                                                  380


<210>  4806
<211>  367
<212>  DNA
<213>  homo sapiens

<400>  4806
aaagatgacc agctttacaa agactgcccg agaacagtat gaaaaactct ccaccatgca       60

caacaacatg atgaagctct atgagaatct tggagaatac ttcatttttg actcaaagac      120

agtgagcata gaagagttct ttggtgatct caacaacttc cgaactttgt ttttggaagc      180

agtgagagaa aacaataaga gaagagaaat ggaagagaag accaggaggg caaaacttgc      240

aaaagagaaa gctgaacaag aaaagttaga acgccagaag aaaaagaaac aactcattga      300

tataaacaaa gagggtgatg agactggtgt gatggataat cttctagaag ccctacaatc      360

aggtgca                                                                367


<210>  4807
<211>  412
<212>  DNA
<213>  homo sapiens

<400>  4807
ggtgtccaga tcagaaattg accttttgga cattcgaaca gagttcaaga agcattatgg       60

ctattcccta tattcagcaa ttaaatcgga tacttctgga gactatgaaa tcacactctt      120

aaaaatctgt ggtggagatg actgaaccaa gaagataatc tccaaaggtc cacgatgggc      180

ttttcccaac agctccacct tacttcttct catactattt aagagaacaa gcaaatataa      240

acagcaactt gtgttcctaa caggaatttt cattgttcta taacaacaac aacaaaagcg      300

attattattt tagagcatct catttataat gtagcagctc ataaatgaaa ttgaaaatgg      360

tattaaagat ctgcaactac tatccaactt atatttctgc tttcaaagtt aa              412


<210>  4808
<211>  94
<212>  DNA
<213>  homo sapiens

<400>  4808
taaaccataa gcttcaggac gcgtctgcag aggtggagcg actgagaaga gaaaaccagg       60

tcttaagcgt gagaatcgcg gacaagaagt acta                                   94


<210>  4809
<211>  469
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (38)..(38)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (128)..(128)
<223>  n is a, c, g, or t

<400>  4809
gtgcgtttag aggtacaccc catgtctcca cagggcanac agcatccgat ttaatctgga       60

tccattccgg cgccttcctc tcccagtcac ccagagggcc ccaaccccgg cggccctttc      120

ttcctcanat gtcctcggct ctataccgtg cctgggtctt ttctctttct ctctgcctgg      180

aacattcctt ctttcccctt ttgtcttgcc cactcctgtt tacccttcaa gtttcaagtt      240

catgtcactg tctcagagag gttttcctgt gctcgccctg tttctctcag gaagccttgc      300

tcttttccat catgcctcta atcacagctt ataatcggat atttatttct gtgtctacag      360

tcttgccctg ccagactgta agccccatgt gggcaggcgc tcatgattgt ttctgattgt      420

ttcacgcatg ctgctaaccc agagcctggg cccaaagcta gttagtact                  469


<210>  4810
<211>  235
<212>  DNA
<213>  homo sapiens

<400>  4810
agtcatctga ggttatgctt tgcaaaaggc tgacggtatg gaatatgttt ccatgtctga       60

gtcttagaaa ctggctgctc attgttagaa agtgatgctt tgtgagacta ttgtcttggg      120

gccaaaaata atcagggatt ttaaattggg caagggacaa ggtgctagaa tcctaagctc      180

tggaaatatt tcatgacact ggtgtattca ctcatgtgtt ccagatgtat tctaa           235


<210>  4811
<211>  256
<212>  DNA
<213>  homo sapiens

<400>  4811
accgtgccta gccaaggatg agatttttaa agtatgtttc agttctgtgt catggttgga       60

agacagagta ggaaggatat ggaaaaggtc atggggaagc agaggtgatt catggctctg      120

tgaatttgag gtgaatggtt ccttattgtc taggccactt gtgaagaata tgagtcagtt      180

attgccagcc ttggaattta cttctctagc ttacaatgga ccttttgaac tggaaaacac      240

cttgtctgca ttcact                                                      256


<210>  4812
<211>  480
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (245)..(245)
<223>  n is a, c, g, or t

<400>  4812
aaaaacacac tactgtattt tggatggatc aaacctcctt aattttaatt tctaatccta       60

aagtaaagag atgcaattgg gggccttcca tgtagaaagt ggggtcagga ggccaagaaa      120

gggaatatga atgtatatcc aagtcactca ggaactttta tgcaggtgct agaaacttta      180

tgtcaaagtg gccacaagat tgtttaatag gagacgaacg aatgtaactc catgtttact      240

gctanaaacc aaagctttgt gtaaaatctt gaatttatgg ggcgggaggg taggaaagcc      300

tgtacctgtc tgtttttttc ctgatccttt tccctcattc ctgaactgca ggagactgag      360

cccctttggg ctttggtgac cccatcactg gggtgtgttt atttgatggt tgattttgct      420

gtactgggta cttcctttcc cattttctaa tcatttttta acacaagctg actcttccct      480


<210>  4813
<211>  257
<212>  DNA
<213>  homo sapiens

<400>  4813
cgagctgata gtgagcggca gaatcaggag taccagcggc tcatggacat caagtcgcgg       60

ctggagcagg agattgccac ctaccgcagc ctgctcgagg gacaggaaga tcactacaac      120

aatttgtctg cctccaaggt cctctgaggc agcaggctct ggggcttctg ctgtcctttg      180

gagggtgtct tctgggtaga gggatgggaa ggaagggacc cttacccccg gctcttctcc      240

tgacctgcca ataaaaa                                                     257


<210>  4814
<211>  472
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (390)..(390)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (395)..(395)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (416)..(417)
<223>  n is a, c, g, or t

<400>  4814
tacctcattt gttgtgtgac tgagtaaaga atttttggat caagcggaaa gagtttaagt       60

gtctaacaaa cttaaagcta ctgtagtacc taaaaagtca gtgttgtaca tagcataaaa      120

actctgcaga gaagtattcc caataaggaa atagcattga aatgttaaat acaatttctg      180

aaagttatgt tttttttcta tcatctggta taccattgct ttatttttat aaattatttt      240

ctcattgcca ttggaataga tatctcagat tgtgtagata tgctatttaa ataatttatc      300

aggaaatact gcctgtagag ttagtatttc tatttttata taatgtttgc acactgaatt      360

gaagaattgt tggttttttc ttttttttgn tttgnttttt tttttttttt tttttnngct      420

tttgacctcc catttttact atttgccaat acctttttct aggaatgtgc tt              472


<210>  4815
<211>  320
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (229)..(230)
<223>  n is a, c, g, or t

<400>  4815
gatgaactga ggtccttgtt ttgttttgtt cataatacaa aggtgctaat taatagtatt       60

tcagatactt gaagaatgtt gatggtgcta gaagaatttg agaagaaata ctcctgtatt      120

gagttgtatc gtgtggtgta ttttttaaaa aatttgattt agcattcata ttttccatct      180

tattcccaat taaaagtatg cagattattt gcccaaagtt gtcctcttnn ttcagattca      240

gcatttgttc tttgccagtc tcattttcat cttcttccat ggttccacag aagctttgtt      300

tcttgggcaa gcagaaaaat                                                  320


<210>  4816
<211>  582
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (316)..(316)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (493)..(493)
<223>  n is a, c, g, or t

<400>  4816
tatatttcct atacgtgtgt ctttaaaaaa aaaatgtgaa cagtgaacgt ttcggttgct       60

gtgactggga agttgttggg tgtgcttttt cagccagctt ctccttccac tgcttaaagt      120

gtccatgatt ctttaaggtg agctgcagtt tatagcccca ggtcatacct aggaggggag      180

cataatgagc tcagggcctc cccaaagtga caaggttagg gagtgcttag cggttttgtg      240

ttcagcctta gctttgttta tagagggagg ttcagtttct tttctgtagt gcttgtaata      300

attctcactc ctaacngcac catcgttgtg tcttgaataa gttagaggta gcattataga      360

ggatctggca taaatatttg cagtagtgag agcctaagcg atggtgattg gtggagcttg      420

aattttaggc tggtgagatg gcagcttttg tgcctgagag gtagtgggtg gttcttaagc      480

ttcagtgatc ccnttttttt tttttttttt ttttttttaa ggaacttgtg ttataatttt      540

ggtaaaagta taaacccact ccctctggac aatacttagc ga                         582


<210>  4817
<211>  552
<212>  DNA
<213>  homo sapiens

<400>  4817
ttcctgtgca agtttggtgc tcaaggcagc ggctttgggc agatggaccg cccttccggc       60

atcgccatca cccccgacgg aatgatcgtt gtggtggact ttggcaacaa tcgaatcctc      120

gtcttctaat tgcatttcct aggtttctgt gtttggggtg tgtgtgcgtg tctctctctc      180

tctctctctc tttctctttc tctctctttt tgaatttcaa agaagaaaca gtctcaggga      240

aatttctttt ttcttttttt tttttaaaga gaacaagaaa agtacaacat tgcttaagtc      300

ctacctcatc tttatttttt tacagatgaa tgtacttatc ttttctgcag ggattgagcc      360

tgtgaagtga taatttctat ctacctcata aatctttaca tttccttctg caacaggccc      420

tcttcccctc ctcagtggag tttgcatttc cctcttcccc tgcgtggggc atgatatgca      480

caagcctggc atctgtatgg ctgggagggc actggatgtg tgtggtgggg tgtattctgt      540

agattgagcc aa                                                          552


<210>  4818
<211>  324
<212>  DNA
<213>  homo sapiens

<400>  4818
tgtccgagtt ggagagtgct ctgcagatgg agccagctgc cttccaggct ttatattctg       60

ctgagaagcc aaagctggaa gatgagcatc tcgttttctt ctgtcagatg ggcaagcggg      120

gcctccaggc cacgcagctg gcccggagtc ttggatacac tggggctcgc aactacgctg      180

gagcctatag agaatggttg gagaaagaga gttaggcagg aggcagctta ctgattgcca      240

ccccctggcc ccttaatggc caccttaact aagggtgtga acgggctgac ttggtgaatt      300

gggcaactcc ttatagtgtt gtgc                                             324


<210>  4819
<211>  566
<212>  DNA
<213>  homo sapiens

<400>  4819
ggtatcacct aaatattctt cagtcacact cactggtatt tctgaggctt tgtgtgttaa       60

caggccttgt aattgacatt attttggtta atgtaacccc aaaattgctt tagtaattgc      120

tctttggcat agtcaaacta taaatgaaaa tggcagcttt acaaatagta tatttaagtg      180

aactctggaa ctatggacat gaaaaaaatg atggctggga tttatgattt ttgtctggca      240

gcaaacaggt ttgtccagaa gtctaataat taagcagtca taaaaagtct gaatttagta      300

aaccagtgta tgatgttatt caaatagttt accttgggta tgagttcatt ttataatgtc      360

tgatgacatt agatctctta aaactttatg tatttttttt agttcaaagg aatagagtct      420

tgaagagaaa aaattatagg gcagaaaaga taagtgttca aaattggcaa ctggactatt      480

attatgtcta gcatctcatt ctaaataact aaagcttgat ttactcttgc taggattatg      540

tgactactag gtaggagcct cttaaa                                           566


<210>  4820
<211>  549
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (316)..(316)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (519)..(519)
<223>  n is a, c, g, or t

<400>  4820
gtgactgata cctaaaagcc ctttcttcct ctagtcgcca gctcatcaga aaaacatact       60

ttgaaaagat gcttgagatt ttcctgctgc atcgcactct agttttgaag gatttacatc      120

ttaggaaata acatgtatac tctagtaaat aagcgattta ggtgttccat tgaacagctt      180

tgattaactt aatgccacca ttgatttcaa agtgaagaaa atgtaacaga agccagtgaa      240

gcaatggaag ctggagtgtg actggaaaaa tactcagcaa acaaagttac caattccata      300

cagagatgat ctggtntctt cttttggaaa atggtattca aattctggaa tggaaatcta      360

gccaccaaaa cgggttaatc aaaagacgtc cttttccatt tttttttgct tttattttct      420

aaatcatttt taagggaatg aaacaggaat gtcatcagag attttttagt acaggcccaa      480

gagcctgttc tctaagaaag aaattgttgc catgttttng attttcgaat aagtgacttt      540

gcaggcttt                                                              549


<210>  4821
<211>  338
<212>  DNA
<213>  homo sapiens

<400>  4821
tggtcagcac ccagcttatc atgcctggtc aagaagcagg ccttgggcag gttccgctga       60

tcgtgggcat cttgctggtg ttgatggctg tggtccttgc atctctgata tataggcgca      120

gacttatgaa gcaagacttc tccgtacccc agttgccaca tagcagcagt cactggctgc      180

gtctaccccg catcttctgc tcttgtccca ttggtgagaa tagccccctc ctcagtgggc      240

agcaggtctg agtactctca tatgatgctg tgattttcct ggagttgaca gaaacaccta      300

tatttccccc agtcttccct gggagactac tattaact                              338


<210>  4822
<211>  247
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (106)..(106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (148)..(148)
<223>  n is a, c, g, or t

<400>  4822
gagcgagtca caccacctga gggttatgaa gtggtcactg tgttccccaa gtgagccagc       60

agatctgacc actgttctcc agcaggcctc tgctgcagct ttttcntctc agtgttctgg      120

ccctctcctc tcttgaaagt tctctgcntt actttggttt tccctctgct tgtaaaacat      180

tgagtcccct ccctgccttg gttaattgac tcacaccagc tgtgcgatgc ccgcttttac      240

aattaaa                                                                247


<210>  4823
<211>  525
<212>  DNA
<213>  homo sapiens

<400>  4823
agcagcgtgg agagctggcc attaaggatg ccaacgccaa gttgtccgag ctggaggccg       60

ccctgcagcg ggccaagcag gacatggcgc ggcagctgcg tgagtaccag gagctgatga      120

acgtcaagct ggccctggac atcgagatcg ccacctacag gaagctgctg gagggcgagg      180

agagccggct ggagtctggg atgcagaaca tgagtattca tacgaagacc accagcggct      240

atgcaggtgg tctgagctcg gcctatgggg gcctcacaag ccccggcctc agctacagcc      300

tgggctccag ctttggctct ggcgcgggct ccagctcctt cagccgcacc agctcctcca      360

gggccgtggt tgtgaagaag atcgagacac gtgatgggaa gctggtgtct gagtcctctg      420

acgtcctgcc caagtgaaca gctgcggcag cccctcccag cctacccctc ctgcgctgcc      480

ccagagcctg ggaaggaggc cgctatgcag ggtagcactg ggaac                      525


<210>  4824
<211>  228
<212>  DNA
<213>  homo sapiens

<400>  4824
caaagagggt gacaagttca agctcaacaa gtcagaacta aaggagctgc tgacccggga       60

gctgcccagc ttcttgggga aaaggacaga tgaagctgct ttccagaagc tgatgagcaa      120

cttggacagc aacagggaca acgaggtgga cttccaagag tactgtgtct tcctgtcctg      180

catcgccatg atgtgtaacg aattctttga aggcttccca gataagca                   228


<210>  4825
<211>  126
<212>  DNA
<213>  homo sapiens

<400>  4825
cactgtggtg cttcagtggc caccagcctc gtcacataca ccagcatctt tctgtacctc       60

ctccctttgg tgacctgaag tcactgtgac agttctccag gaaggaggag cttcctactt      120

ttgagt                                                                 126


<210>  4826
<211>  577
<212>  DNA
<213>  homo sapiens

<400>  4826
cctcgcggct taccgactgg aagacacgtt tggcccagac ccaactatga ttagagccaa       60

ctgcctggtc cagaccacag agtggagcgc ctgttccaag acctgtggga tgggcatctc      120

cacccgggtt accaatgaca acgcctcctg caggctagag aagcagagcc gcctgtgcat      180

ggtcaggcct tgcgaagctg acctggaaga gaacattaag aagggcaaaa agtgcatccg      240

tactcccaaa atctccaagc ctatcaagtt tgagctttct ggctgcacca gcatgaagac      300

ataccgagct aaattctgtg gagtatgtac cgacggccga tgctgcaccc cccacagaac      360

caccaccctg ccggtggagt tcaagtgccc tgacggcgag gtcatgaaga agaacatgat      420

gttcatcaag acctgtgcct gccattacaa ctgtcccgga gacaatgaca tctttgaatc      480

gctgtactac aggaagatgt acggagacat ggcatgaagc cagagagtga gagacattaa      540

ctcattagac tggaacttga actgattcac atctcat                               577


<210>  4827
<211>  465
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (106)..(106)
<223>  n is a, c, g, or t

<400>  4827
cctctctcac tttctatagc tttgttggac cagatggtga ggaaaggaat ggcctcttcc       60

cttctagagg gggctggctg gagtgagacc tggggcttgg cctggnaacc caccacacag      120

ccccaaagtc aggaagcctg gggaaaccag agctgagacc tcttcaacag ggtttctttg      180

agatcctaca cctccattgg gccctttttc agtcttcaat gggggcccag ttggctctag      240

aaggagaaga ggtgaagcag gatcctttgc cctgggggag tctgagggcg cggtccttgg      300

actcattcag gccgtctttg tagttggggg agttccactg ggcgatccca gcccctcccc      360

acccaccctc taatggacct cctcatagaa gccccatttc acttttgttt tatctacctc      420

ttagcaaaac aatagataaa ttaggtagtg gcagctccac ttgct                      465


<210>  4828
<211>  270
<212>  DNA
<213>  homo sapiens

<400>  4828
cgcctcgccg gatctgaggg agaacaagac cgatcggcgg ccactgcgcc cttaactgca       60

tccagcctgg ggctgaggct gaggcactgg cgaggagagg gcgctcctct ctgcacacct      120

actagtcacc agagacttta gggggtggga ttccactcgt gtgtttctat tttttgaaaa      180

gcagacattt taaaaaatgg tcacgtttgg tgcttctcag atttctgagg aaattgcttt      240

gtattgtata ttacaatgat caccgactga                                       270


<210>  4829
<211>  356
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (194)..(194)
<223>  n is a, c, g, or t

<400>  4829
gaagccggac ggcagggatg ggccccaact tcgccctgcc cacttgactt caccaaatcc       60

cttccttgga gactaaacct ggtgctcagg agcgaaggac tgtgaacttg tggcctgaag      120

agccagagct agctctggcc accagctggg cgacgtcacc ctgctcccac cccaccccca      180

agttctaagg tctnttcaga gcgtggaggt gtggaaggag tggctgctct ccaaactatg      240

ccaaggcggc ggcagagctg gtcttctggt ctccttggag aaaggttctg ttgccctgat      300

ttatgaactc tataatagag tatataggtt ttgtaccttt tttacaggaa ggtgac          356


<210>  4830
<211>  348
<212>  DNA
<213>  homo sapiens

<400>  4830
gattcacata caaaaagctg cacatattta atgtatccta ttgtgtaatt aatttttaat       60

ttttttgtgt acttcctaaa cttatagtcc tgcgagtctg ggaacagatc tgtttttcac      120

ttatcctgat ttaatgacag tttccaacat tgttttgtta ttacaagtag gggatctttt      180

tttttgcccg tttaatgaag atactaaaaa taatgcactg gaaggagtgg aagagttgga      240

aaatttgtaa ccatcataat acaggtgtaa taggtttggg aaagaatcct caaaaatgtt      300

aaagcaaggg aggaaagttt gttgagaagc aagatgttct tctctcct                   348


<210>  4831
<211>  325
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (114)..(114)
<223>  n is a, c, g, or t

<400>  4831
gatctgcaca gtttggtttt tgcacaaaag tcatttaaaa aaatctgagt aattgtcaaa       60

tattaaaaga aagatattct tcctgtaagg aatacagttt ttagtcaaag tggnccatta      120

catcctcttt ttaatttaca taatacagat acttgagaaa gttgttgtgg tgttgtatgc      180

caagaaaatt ctttttattg gtgcctatat tgtaacaatt atttttaatg cattgtattt      240

tgaagtaacg gttcagttaa atttttcacc tgctgtgtaa ctgaaacaca attacagttt      300

ataatcatct gtagaagtct ggaga                                            325


<210>  4832
<211>  272
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (207)..(207)
<223>  n is a, c, g, or t

<400>  4832
gaaactgact gggtctcttt gcctaccgta ttaacattaa acattgatgt tctgtattct       60

gtactttact gcacccagca gactttcaac aactcattga tccaaagata catgcacagt      120

ctgagcacca gctatggtgc tcataacttc tttaagactt gaaccctttc aatctgtgtg      180

attcattaaa ttggaccatt gatgatnaga atacacattg tatgtttctg tgcacatgac      240

agtgtgtgtg tgtgcacgta catactgtat ag                                    272


<210>  4833
<211>  556
<212>  DNA
<213>  homo sapiens

<400>  4833
tcagtgcatt actgcctcag acactccagt tgtcctcgtc agcgttggag ctgacctgcc       60

cgtctctgcc ttagacccaa gtcagcttct ttgggctgaa gagccgacga acagaaccac      120

tctctactca ggcactggct taagtgttaa cagagaaaat gcaaaatgtt tcacaaccaa      180

agaggagctg gggaagacag tgcctcagct actgactcct gggctgatgg gcgaatcttc      240

agaatccttt agtgcctcag aagatgaagg ccacagggaa taccaagcca atgactctga      300

ctcggacggg cctatcttgt acaccgatga tgaggacgaa gacgaagatg aggatggcag      360

tggagaaagt gctttggcaa gtaaaatacg ccggagggat actcttgcta tcaaacttgg      420

caacagacca tctaagaaag aactagagga caaaaacatc ttgcagcgta catctgaaga      480

agagaggcag gaaatccgac aacaaattgg aaccaagtta gtcaggaggc tgagccagag      540

gcccacaact gaagaa                                                      556


<210>  4834
<211>  517
<212>  DNA
<213>  homo sapiens

<400>  4834
gtgtttgtcg cctttatcat cttggggtcc ctggtggcag cctgttgctg cagatgtctc       60

cggcctaagc aggatcccca gcagagccga gccccagggg gtaaccgctt gatggagacc      120

atccccatga tccccagtgc cagcacctcc cgggggtcgt cctcacgcca gtccagcaca      180

gctgccagtt ccagctccag cgccaactca ggggcccggg cgcccccaac aaggtcacag      240

accaactgtt gcttgccgga agggaccatg aacaacgtgt atgtcaacat gcccacgaat      300

ttctctgtgc tgaactgtca gcaggccacc cagattgtgc cacatcaagg gcagtatctg      360

catcccccat acgtggggta cacggtgcag cacgactctg tgcccatgac agctgtgcca      420

cctttcatgg acggcctgca gcctggctac aggcagattc agtccccctt ccctcacacc      480

aacagtgaac agaagatgta cccagcggtg actgtat                               517


<210>  4835
<211>  417
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (81)..(81)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (93)..(98)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (100)..(102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (104)..(104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (108)..(108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (110)..(112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (114)..(117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (119)..(120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (123)..(127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (129)..(136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (141)..(146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (148)..(149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (153)..(153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (155)..(159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (163)..(163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (165)..(165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (170)..(171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (174)..(175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (177)..(177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (179)..(184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (187)..(187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (189)..(189)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (191)..(194)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (196)..(197)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (199)..(202)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (204)..(204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (206)..(207)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (210)..(211)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (219)..(219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (223)..(223)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (231)..(231)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (240)..(240)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (246)..(246)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (253)..(253)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (261)..(261)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (267)..(267)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (274)..(274)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (285)..(286)
<223>  n is a, c, g, or t

<400>  4835
actcctgcaa taacttcatc tatggaggct gccggggcaa taagaacagc taccgctctg       60

aggaggcctg catgctccgc ntgcttccgc cannnnnngn nncntccncn nncnnnngnn      120

tcnnnnntnn nnnnnntggc nnnnnngnnt ggngnnnnnt ggngnggctn ngtnngngnn      180

nnnnggntnt nnnntnncnn nntncnnggn ngcctccant ggntctacct ngatccgggn      240

tggcancgga ggnaaccagg nagcgtngcc ctgncgcacc gtctnnggag ctccggagat      300

gacaaggagc agctggtgaa gaacacatat gtcctgtgac cgccctgtcg ccaagaggac      360

tggggaaggg aggggagact atgtgtgagc tttttttaaa tagagggatt gactcgg         417


<210>  4836
<211>  333
<212>  DNA
<213>  homo sapiens

<400>  4836
tgacctgccc caaaaccaaa ttaaaaatat cctataagga tgccataaat cgctccatgg       60

tagaagatat cactgggctg cgccttctgg aagccgcctc cgtgtcgtcc aagggcttac      120

ccagccctta caacatgtct tcggctccgg ggctcccgct ccggctcccg ctcgggatct      180

cgctccggat ctcgctccgg gtcccgcagt gggtcccgga gaggaagctt tgacgccaca      240

gggaattctt cctactctta ttcctactca tttagcagta gttctattgg gcactagtag      300

tcagttggga gtggttgcta taccttgact tca                                   333


<210>  4837
<211>  511
<212>  DNA
<213>  homo sapiens

<400>  4837
cctatcctgt cccttgttta taacattgag aggttttcta gggcacatac tgagtgagag       60

cagtgttgag aagtcgggga aaatggtgac tacttttaga gcaaggctgg gcatcagcac      120

ctgtccagct ctacttgtgt gatgtttcag gaactcagcc cctttttctg cctaggataa      180

ggagctgaaa gattaacttg gatcttctaa tggtccaaat cttttggtca caataaagag      240

tctccaaatt agagactgca tgttagttct ggatggattt ggtggcctga catgataccc      300

tgccagctgt gaggggaccc cgtttttaag atgcatggcc aagctctctg caaatggaaa      360

tgcttacact gggtgttggg gatgtttgct acctcctgct atttttgtgg ttttggttct      420

cccactatgg taggacccct ggccagcatt gtggcttgtc atgtcagccc cattgactac      480

cttctcatgc tctgaggtac tactgcctct g                                     511


<210>  4838
<211>  429
<212>  DNA
<213>  homo sapiens

<400>  4838
ataacctata cggtagttgc tttagggggt ggggggatgc tatctgttag tgcttaaaag       60

ggggtaaatg cttgccgctt tagaggtgga tggtgctcat aaaaggcccc agtcgggggt      120

atttaaaaag gactgaacag aaatccttag ctagtagaat ggcagcacgc tgtaaaatta      180

ttactgtatt gtgtactggc tataagatgt agacaccttt cagtaagcca atcatttgta      240

accattctag cagtgtcata ttaggttaat aaggctgctg tgttttaaag ggcattttta      300

tttgggtttt ggtgaaattc tttaatttgt tgattatatt cacataaaat cagcattcat      360

tgacacatag ctctaatgac atatgtatga aaaaccatac actggatgac ctagtcgatt      420

atttaagca                                                              429


<210>  4839
<211>  525
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (456)..(456)
<223>  n is a, c, g, or t

<400>  4839
attccctcaa ctctgtgcat atgtgaatat cactgatgtg aacacattgt tcatttacat       60

aggtaaaata ttactctgtt tacagcaaaa ggctacctca tagttgatac atagcacacc      120

tgtatgtatg ctgttccagc cttacaggtg gctgataatt ctctggtaca gaaccttttt      180

atctgtatta taaatagcaa ttcacaactg catgtttctg acaaacactt gtgaataatg      240

aagcatctcg ttttagttag caaagtctcc aaacatttcc ttaaaataat catgtattta      300

gtttaaagaa ttatgggcac tgttcaactt aagcaaaaca gaacacggaa gcagtcttag      360

aagcaccact ttgcccagag gtggaggttg gaaggggtag cagggagagg ggttggtgta      420

tgcaggtatt catgctaggc aaagagttta aaagangcca atgtccttca tttactgtct      480

gtgctgccct gaagccaagc gtattgcagc attatagccc caggc                      525


<210>  4840
<211>  156
<212>  DNA
<213>  homo sapiens

<400>  4840
agagttaacc tgaaagagtg ctttacagct gcaaatctaa ttcattcaag tgatcctgac       60

ttccaaattt tggaggatgg ttcagtctat acaacaaata ctattctatt gtcctcggag      120

aagagaagtt ttaccatatt actttccaac actgag                                156


<210>  4841
<211>  543
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (464)..(464)
<223>  n is a, c, g, or t

<400>  4841
aattctgaac cccatctttg gcaggcatac atatttcact gtttccaaag ctatctactc       60

tgccaaacaa cacccagtcc tattccaaac tctcaacgat tctatcttgt tcctgttttt      120

ctatgtattt atggttgccg tttgtgtctg atttgatttt actgtttttt ccctgatttt      180

atggagtagc attgtgacct gttttccttt gtcttatata actttagtaa actaaccact      240

gtcaatgatt gagggcaggt ggcacgtggg gaagagggga cttggcacgc agtggctacc      300

tgggcatttg tggtcatttc agtttccatc tccccagcgg gggctccctg ggtgaaaggc      360

cacagtattt tgggttggta ggcaaattgc aacattctgg acatggcctg aggaaggcct      420

cttcttataa gattctcaga ccaaattcta gaccaaagac acangcagac caagtcccca      480

ggccccgcct ggaaggaagt cgttcctcaa ctctccccaa ggcacctgtc tccaatcaga      540

gcc                                                                    543


<210>  4842
<211>  169
<212>  DNA
<213>  homo sapiens

<400>  4842
aaggagatct gtgttcgtac agtgtgtgcc catgaggagc tcctccgagc tgacctctgt       60

cgggacaagt tctccaaatg tggcgtgatg gccagcagcg gcctgtgcca atccgtggcg      120

gcctcctgtg ccaggagctg tgggagctgc tagggtggtg ctggcatcc                  169


<210>  4843
<211>  318
<212>  DNA
<213>  homo sapiens

<400>  4843
ggaagttggc catcgagaac accatggctc tgttaggtac ggacggaaaa agagtctcag       60

aaatctttcc caaggaaatc ctggcccctt cagtgaatgt ggaccctgtt gtgtggaacc      120

agtacaccag catgctcaat ggcggtctgg ccgtgaagac caatgagatc tctgtgatcc      180

agagtggggg ggttcctacc ctcccggttt ccttgggggc cacctccgtt gtgaataacg      240

ccactgtctc caagatggat ggctcccagt cgggtatcag tgcagatgtg gaaaaaccaa      300

gtgctactga cggcgttc                                                    318


<210>  4844
<211>  475
<212>  DNA
<213>  homo sapiens

<400>  4844
aagacttatc gtaagctgca ccccaatcag cccttttaca tcctcaagcc ccagatgcct       60

tgggagctat gggacattct tcaagaaatc tccccagaag agattcagcc aaacccccca      120

tcctctggga tgcttggtat catcatcatg atgacgctgt gtgaccaggt ggatatttat      180

gagttcctcc catccaagcg caagactgac gtgtgctact actaccagaa gttcttcgat      240

agtgcctgca cgatgggtgc ctaccacccg ctgctctatg agaagaattt ggtgaagcat      300

ctcaaccagg gcacagatga ggacatctac ctgcttggaa aagccacact gcctggcttc      360

cggaccattc actgctaagc acaggctcct cactcttctc catcaggcat taaatgaatg      420

gtctcttggc caccccagcc tgggaagaac attttcctga acaattccag cctgc           475


<210>  4845
<211>  444
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (314)..(316)
<223>  n is a, c, g, or t

<400>  4845
acttgtccag ctgagcgcca ggatggaaca cggccacatc aaagaggctg aggctggcac       60

aggacatgcg gtagccagca cacagggcag tgagggaggg ctgtcatctg tgcactgccc      120

atggacaggc tggctccaga tgcagggcag tcattggctg tctcctagga aacccatatc      180

cttaccctcc ttgggactga aggggaaccc cggggtgccc acaggccgcc ctgcgggtga      240

acaaagcagc cacgaggtgc aacaaggtcc tctgtcagtc acagccaccc ctgagatccg      300

gcaacatcaa cccnnngagt cattcgttct gtggagggac aagtggactc agggcagcgc      360

caggctgacc acagcacagc caacacgcac ctgcctcagg actgcgacga aaccggtggg      420

gctggttctg taattgtgtg tgat                                             444


<210>  4846
<211>  220
<212>  DNA
<213>  homo sapiens

<400>  4846
ctggaactgc ggcaaagtag gagaagaaat ggggaggact cgggtggggg aggacgtccc       60

ggctgggatg aagtctggtg gtgggtcgta agtttaggag gtgactgcat cctccagcat      120

ctcaactccg tctgtctact gtgtgagact tcggcggacc attaggaatg agatccgtga      180

gatccttcca tcttcttgaa gtcgccttta gggtggctgc                            220


<210>  4847
<211>  191
<212>  DNA
<213>  homo sapiens

<400>  4847
agaagggctc caccatggag cgctggggac agaagcacat gaccgccgtg gtgaagctgt       60

tcgggccctt taccaggaat tactatgttc gggccgtcct gcatctcctg ctctcggtgc      120

ccgccggctt cctgctggcc accatccttg ggaccgcctg cctggccatt gcgagcggca      180

tctacctact g                                                           191


<210>  4848
<211>  393
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (53)..(53)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (71)..(71)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (81)..(81)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (88)..(88)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (105)..(109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (111)..(112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (115)..(115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (124)..(124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (129)..(133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (135)..(135)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (137)..(140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (142)..(142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (154)..(154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (160)..(160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (165)..(166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (173)..(174)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (176)..(180)
<223>  n is a, c, g, or t

<400>  4848
ggagctgctg agacgacgct cacagagctg agacgtacag tccagtcctt ggnagatcga       60

cctggactcc natgagaaat nctgaagngc cagcttggag aacannnnng nnggnaggtg      120

gagncccgnn nnncncnnnn anagatggag cagntcaacn ggganncctg ctnncnnnnn      180

gagtcagagc tggcacagac ccgggcagag ggacagcgcc aggcccagga gtatgaggcc      240

ctgctgaaca tcaaggtcaa gctggaggct gagatcgcca cctaccgccg cctgctggaa      300

gatggcgagg actttaatct tggtgatgcc ttggacagca gcaactccat gcaaaccatc      360

caaaagacca ccacccgccg gatagtggat ggc                                   393


<210>  4849
<211>  149
<212>  DNA
<213>  homo sapiens

<400>  4849
aaatagcccc gagattcacc gtcctagagc ttaggcctgt cttccacccc tcctgacccg       60

tatagtgtgc cacaggacct gggtcggtct agaactctct caggatgcct tttctacccc      120

atccctcaca gcctcttgct gctaaaata                                        149


<210>  4850
<211>  79
<212>  DNA
<213>  homo sapiens

<400>  4850
tgaactgaag gcgaaactgc agagttcccc tgactaccta caggtccttg aggagcaaac       60

agctttgaac aagatctag                                                    79


<210>  4851
<211>  113
<212>  DNA
<213>  homo sapiens

<400>  4851
gggaagggcc gcgttggagg ccgctggaag tgaggatgcc gccccggaca gtggcacctg       60

ggaagcctgg gagtgtttgt cccatcggta gcttgaaata aacgctcccc tca             113


<210>  4852
<211>  272
<212>  DNA
<213>  homo sapiens

<400>  4852
atgctgagca ataccacagc tgttgccgag gcctgggctc gcctggacca caagtttgac       60

ctgatgtatg ccaagcgtgc ctttgttcac tggtacgtgg gtgaggggat ggaggaaggc      120

gagttttcag aggcccgtga ggacatggct gcccttgaga aggattatga ggaggttgga      180

gcagatagtg ctgacggaga ggatgagggt gaagagtatt aacctgtgtg ctgtactttt      240

acactccttt gtcttggaac tgtcttattt tt                                    272


<210>  4853
<211>  166
<212>  DNA
<213>  homo sapiens

<400>  4853
tggtagttgg cactgaaaaa acttttcagg gctgtgtgaa ttgtgtgact gattgtccta       60

gatgcactac tttatttaaa aaataatgtt cataaggagt caatatgtag tttaagagac      120

aatcagtgtg tgtcttataa atggtacatc tgtggttttt aatctg                     166


<210>  4854
<211>  226
<212>  DNA
<213>  homo sapiens

<400>  4854
atgctcacag taccacctca agtgcctccc cagctcaatc tccttgttac agtaaccagt       60

cagatgacgg ctcagataca gagatggctt ctggttctaa cagaacacca gttttttcct      120

ttttagatct cacttactgg aaaagacaga agatatgttg tgggatcatc tataaaggcc      180

gttttgggga agtcctcatt gacacacatc tcttcaagcc ttgctg                     226


<210>  4855
<211>  326
<212>  DNA
<213>  homo sapiens

<400>  4855
aatctactac caagaaccag ctccaagaag aaaacatctc tgggaaacag taccaaaagg       60

agtcactgaa ttgtcattgg aggagtccag gatagctctt catgttattt tcaccttgag      120

gaattgtcca ttacatctat gagccttatg tgtggctttc tccgatatag aaacctatca      180

ggtgtctttt agatcatttc aaaacactgg cttattcttt cttatgtttc caactgaagt      240

ctgcatccca agatgtagtt tcactgctac cccatatggc acccttgtac gaatttgaaa      300

aaagtactca ctctaggcac atgcag                                           326


<210>  4856
<211>  496
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (59)..(59)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (69)..(69)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (80)..(80)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (91)..(91)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (96)..(96)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (104)..(104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (109)..(109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (117)..(117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (124)..(124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (128)..(128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (135)..(135)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (142)..(143)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (154)..(154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (161)..(161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (219)..(219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (227)..(227)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (241)..(241)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (244)..(244)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (263)..(263)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (265)..(266)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (269)..(269)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (271)..(273)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (275)..(280)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (282)..(282)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (287)..(287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (302)..(302)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (323)..(323)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (424)..(424)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (429)..(431)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (433)..(444)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (446)..(446)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (448)..(448)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (450)..(452)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (454)..(455)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (457)..(457)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (460)..(462)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (465)..(468)
<223>  n is a, c, g, or t

<400>  4856
agtatttgat aggtacaaga gttacagccc ttatgacatg ttggaaagca tcaggaaang       60

aggttaaang gagacctggn aaaatgcttt ncctgnaacc tggnttcang tgcattncag      120

aacnaagncc cctgntattt tnnctgatcg gctngtatga nctccatgaa gggcaagggg      180

acgcgagata aggtcctgat cagaatcatg gtctcccgnc agtgaangtg gacatgttga      240

naanattagg tctgaattca agnannaang nnngnnnnnn cnctgtnact attatatcca      300

gncaagacac taagggcgac tancagaaag cgctgctgta cctgtgtggt ggagatgact      360

gaagcccgac acggcctgag cgtccagaaa tggtgctcac catgcttcca gctaacaggt      420

ctanaaaann nannnnnnnn nnnncngncn nngnngngcn nnccnnnngt cccagctagt      480

ccggagctga ggcagg                                                      496


<210>  4857
<211>  224
<212>  DNA
<213>  homo sapiens

<400>  4857
gttttgagtc agctgatttt cacttcccac tgaggttgtc ataacatgca aattgcttca       60

attttctctg tggcccaaac ttgtgggtca caaaccctgt tgagataaag ctggctgtta      120

tctcaacatc ttcatcagct ccagactgag actcagtgtc taagtcttac aacaattcat      180

cattttatac cttcaatggg aacttaaact gttacatgta tcac                       224


<210>  4858
<211>  84
<212>  DNA
<213>  homo sapiens

<400>  4858
tgaggctgtc cctgtaggaa gaaagctctg ggactgagct gtacagtatg gttgccccta       60

tccaagtgtc gctatttaag ttaa                                              84


<210>  4859
<211>  442
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (327)..(327)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (391)..(392)
<223>  n is a, c, g, or t

<400>  4859
atccttccaa ggtccaccgt gatcaacatc cacagcgaga cctccgtgcc cgaccatgtc       60

gtctggtccc tgttcaacac cctcttcttg aactggtgct gtctgggctt catagcattc      120

gcctactccg tgaagtctag ggacaggaag atggttggcg acgtgaccgg ggcccaggcc      180

tatgcctcca ccgccaagtg cctgaacatc tgggccctga ttctgggcat cctcatgacc      240

attggattca tcctgttact ggtattcggc tctgtgacag tctaccatat tatgttacag      300

ataatacagg aaaaacgggg ttactangta gccgcccata gcctgcaacc tttgcactcc      360

actgtgcaat gctggccctg cacgctgggg nnctgttgcc cctgccccct tggtcctgcc      420

cctagataca gcagtttata cc                                               442


<210>  4860
<211>  378
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (100)..(100)
<223>  n is a, c, g, or t

<400>  4860
gggttttcaa gtttactcat ttctatggtt gcaaataact ctaaaactta ttatataaac       60

tttcatatta taggcagaac acaatggcta aatatctgtn tgcatgtact ttaaagttta      120

ttataaaata taaacagata tataaagatg ttgactctta cctgtgattt tgcatggtca      180

gactcggtgt caggtacgga gaggattctc atgactgtct tacctctact gaatattcta      240

gtgagttata tgatttacgg agtgattaac agaggtctat ataaagttac ttttcccctt      300

tacttaatta tattgtagtg tgcagataac aaaactgcta ccttctcatc caagtggtct      360

gtagaattca tgtccctt                                                    378


<210>  4861
<211>  183
<212>  DNA
<213>  homo sapiens

<400>  4861
aacctacagc atattcttca cgcagagatt ttcatctatt atactttatc aaagattggc       60

catgttccac ttggaaatgg catgcaaaag ccatcataga gaaacctgcg taactccatc      120

tgacaaattc aaaagagaga gagagatctt gagagagaaa tgctgttcgt tcaaaagtgg      180

agt                                                                    183


<210>  4862
<211>  337
<212>  DNA
<213>  homo sapiens

<400>  4862
gccaagcgca agagatcagc gcctgagaag tcgtcgggcg atgtccccgc gccgtgtccc       60

tctccaagcg ccgcccctgg cgtgggctcg gtggagcaga ccccgcgcaa gaggctgcgg      120

tgagccaatt tagagcccaa agagccccga gggaacctgc cggggcagcg gacgttggaa      180

gggcgctggg cctcggctgg gaccgttcat gtagcagcaa ccggcggcgg ctgccgcaga      240

gcagcgttcg gttttgtttt taaattttga aaactgtgca atgtattaat aacgtctttt      300

tatatctaaa tgtattctgc acgagaaggt acactgg                               337


<210>  4863
<211>  270
<212>  DNA
<213>  homo sapiens

<400>  4863
atcctgtacc aaatctgaca tattatgcct gaatgactcc actgtttttc tctaatgctt       60

gatttaggta gccttgtgtt ctgagtagag cttgtaataa atactgcagc ttgagttttt      120

agtggaagct tctaaatggt gctgcagatt tgatatttgc attgaggaaa tattaatttt      180

ccaatgcaca gttgccacat ttagtcctgt actgtatgga aacactgatt ttgtaaagtt      240

gcctttattt gctgttaact gttaactatg                                       270


<210>  4864
<211>  347
<212>  DNA
<213>  homo sapiens

<400>  4864
tctgttatta atgttgccac tgctttctgt ttgtctgcac tttcttgata aatatttgct       60

atcgttttac tccagtcatt cgatgttgct gagatttaca tatgactctt gtcaacatct      120

catcttttga cccaatctta ttcatttaat aagaggtctc attcatttgc atggaaaaat      180

gctcattgta tattgcaaag tgaaaataac gagttgcaaa acagtgtata catatatgtg      240

tgtatatatg tacactttat ttgtacattt ctatgtgaca taatgcaaag gaaagtgtct      300

gattttatta tacaccaaag gttaacagtg aatctctgtg tgatctc                    347


<210>  4865
<211>  383
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (169)..(169)
<223>  n is a, c, g, or t

<400>  4865
acactctcca aagaacttga cctaccttat gggttccata tttttcttct taaatgtgca       60

tcaatcatgc cttgccccca acctttaaat atattcttag acctggtaaa tgcactcaga      120

cttgcgtctt taggaatttt taactttctt tcactacatt ggcacttana attttttctt      180

tataaagctt tttgaaggtc ataaacaaag accataattg atgatagacc taatacattt      240

cctctgtgtg tgtgtgtaac attccaaata cttttttttt cttttccact gtttgtaagg      300

tgcaacaatt taatattttt aagggacttt ttaagagttc cttaagaacc aatttaaaat      360

tacttcagtg caatcctaca cag                                              383


<210>  4866
<211>  93
<212>  DNA
<213>  homo sapiens

<400>  4866
ccacgcttat gagttcagga tctacggcaa tgtgaatcat tcagatgttt acaataaaaa       60

acaccacatg agtaaatgaa ttcactaatg tta                                    93


<210>  4867
<211>  403
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (138)..(138)
<223>  n is a, c, g, or t

<400>  4867
cgaggtgtgt ttgaccggag actcaggggc cggcgagttc aagttcctga agccgattat       60

tcctaacctt ttgccccagg gcgctggtga agaaataggg aaaactgctg ccttccggaa      120

tagctttgga ttaaattnag agatctcgtg atgacgcgtt gttttctgcc atttatccca      180

aactttttca gatctagaat tcgagagtgt catggacaaa aatttcacct tgagattgag      240

cttttatttc cctttttaat ggatttgtct gttgaacttc atgctgtcca agtgttgaaa      300

agtcaatttt atttcattgc atttatttac atagtgtcat tccaaatcca tgcatgctgt      360

tgattttcct gagatttttt tctcttcttg ttggtatttg ttg                        403


<210>  4868
<211>  480
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (47)..(47)
<223>  n is a, c, g, or t

<400>  4868
tattcccttg ttgatttctg ttaacttgaa agatttggga ttttttnccc cacctcatca       60

tagatgggaa cttttgtttt cagtgcaaac aatgttggag ctgtaatagt aagagctttc      120

ttacaaagct ttgtattact gtgtggtttt gttttttttg ttgttgttta tttgattttg      180

attttttttt cttttatgtg atctttggga aaacacattc agaattatat ctcgtttcta      240

cttaaatgta gtgcttaggg ttaatttttt gtactgaagt ctttattggt gggtgcatgc      300

tactgggaac aagtttttgt acaaaagctt caatcagaat cactgtgcat tactgagact      360

ctgtttatca ctagccttct gtccctcccg cagaagactg ttggattgaa caaaataata      420

tgtattttga tttacttaaa gtgcttgtaa atttcttagg gacctgccac ttttgactgt      480


<210>  4869
<211>  459
<212>  DNA
<213>  homo sapiens


<220>
<221>  misc_feature
<222>  (211)..(211)
<223>  n is a, c, g, or t

<400>  4869
gccctacctt tgaatgttag tgaatactgt gtgcctagag gaaaccgtag gcggttccgc       60

gttaggcagc ccatcctgca gtatagatgg gacataatgc ataggcttgg agagccacag      120

gcaaggatga gagaggagaa tatggaaagg attggggagg aggtgagaca gctgatggaa      180

aagctgaggg aaaagcagtt gagtcatagt ntgcgggcag tcagcactga tccccctcac      240

catgaccatc acgatgagtt ttgccttatg ccctgaatcc tgatggtttc cctgaagtta      300

atagggagac ccctgcttcc taaacttaca catttgtggt gtacctttgt cgtaaacgtt      360

ttgatgttac ctatttcttg tgggtctcct attaccagct tctaaatgaa tgttgttttt      420

gacccagttt gtaagtttct gtcagcagga gagttttac                             459


<210>  4870
<211>  1563
<212>  DNA
<213>  homo sapiens

<400>  4870
gctcagcatt tggggacgct ctcagctctc ggcgcacggc ccagcttcct tcaaaatgtc       60

tactgttcac gaaatcctgt gcaagctcag cttggagggt gatcactcta cacccccaag      120

tgcatatggg tctgtcaaag cctatactaa ctttgatgct gagcgggatg ctttgaacat      180

tgaaacagcc atcaagacca aaggtgtgga tgaggtcacc attgtcaaca ttttgaccaa      240

ccgcagcaat gcacagagac aggatattgc cttcgcctac cagagaagga ccaaaaagga      300

acttgcatca gcactgaagt cagccttatc tggccacctg gagacggtga ttttgggcct      360

attgaagaca cctgctcagt atgacgcttc tgagctaaaa gcttccatga aggggctggg      420

aaccgacgag gactctctca ttgagatcat ctgctccaga accaaccagg agctgcagga      480

aattaacaga gtctacaagg aaatgtacaa gactgatctg gagaaggaca ttatttcgga      540

cacatctggt gacttccgca agctgatggt tgccctggca aagggtagaa gagcagagga      600

tggctctgtc attgattatg aactgattga ccaagatgct cgggatctct atgacgctgg      660

agtgaagagg aaaggaactg atgttcccaa gtggatcagc atcatgaccg agcggagcgt      720

gccccacctc cagaaagtat ttgataggta caagagttac agcccttatg acatgttgga      780

aagcatcagg aaagaggtta aaggagacct ggaaaatgct ttcctgaacc tggttcagtg      840

cattcagaac aagcccctgt attttgctga tcggctgtat gactccatga agggcaaggg      900

gacgcgagat aaggtcctga tcagaatcat ggtctcccgc agtgaagtgg acatgttgaa      960

aattaggtct gaattcaaga gaaagtacgg caagtccctg tactattata tccagcaaga     1020

cactaagggc gactaccaga aagcgctgct gtacctgtgt ggtggagatg actgaagccc     1080

gacacggcct gagcgtccag aaatggtgct caccatgctt ccagctaaca ggtctagaaa     1140

accagcttgc gaataacagt ccccgtggcc atccctgtga gggtgacgtt agcattaccc     1200

ccaacctcat tttagttgcc taagcattgc ctggccttcc tgtctagtct ctcctgtaag     1260

ccaaagaaat gaacattcca aggagttgga agtgaagtct atgatgtgaa acactttgcc     1320

tcctgtgtac tgtgtcataa acagatgaat aaactgaatt tgtactttag aaacacgtac     1380

tttgtggccc tgctttcaac tgaattgttt gaaaattaaa cgtgcttggg gttcagctgg     1440

tgaggctgtc cctgtaggaa gaaagctctg ggactgagct gtacagtatg gttgccccta     1500

tccaagtgtc gctatttaag ttaaatttaa atgaaataaa ataaaataaa atcaaaaaaa     1560

aaa                                                                   1563


<210>  4871
<211>  1665
<212>  DNA
<213>  homo sapiens

<400>  4871
gctcagcatt tggggacgct ctcagctctc ggcgcacggc ccagggtgaa aatgtttgcc       60

attaaactca catgaagtag gaaatattta tatggataca aaaggcacct gcatgggata      120

atgtcaaatt tcatagatac tgctttgtgc ttccttcaaa atgtctactg ttcacgaaat      180

cctgtgcaag ctcagcttgg agggtgatca ctctacaccc ccaagtgcat atgggtctgt      240

caaagcctat actaactttg atgctgagcg ggatgctttg aacattgaaa cagccatcaa      300

gaccaaaggt gtggatgagg tcaccattgt caacattttg accaaccgca gcaatgcaca      360

gagacaggat attgccttcg cctaccagag aaggaccaaa aaggaacttg catcagcact      420

gaagtcagcc ttatctggcc acctggagac ggtgattttg ggcctattga agacacctgc      480

tcagtatgac gcttctgagc taaaagcttc catgaagggg ctgggaaccg acgaggactc      540

tctcattgag atcatctgct ccagaaccaa ccaggagctg caggaaatta acagagtcta      600

caaggaaatg tacaagactg atctggagaa ggacattatt tcggacacat ctggtgactt      660

ccgcaagctg atggttgccc tggcaaaggg tagaagagca gaggatggct ctgtcattga      720

ttatgaactg attgaccaag atgctcggga tctctatgac gctggagtga agaggaaagg      780

aactgatgtt cccaagtgga tcagcatcat gaccgagcgg agcgtgcccc acctccagaa      840

agtatttgat aggtacaaga gttacagccc ttatgacatg ttggaaagca tcaggaaaga      900

ggttaaagga gacctggaaa atgctttcct gaacctggtt cagtgcattc agaacaagcc      960

cctgtatttt gctgatcggc tgtatgactc catgaagggc aaggggacgc gagataaggt     1020

cctgatcaga atcatggtct cccgcagtga agtggacatg ttgaaaatta ggtctgaatt     1080

caagagaaag tacggcaagt ccctgtacta ttatatccag caagacacta agggcgacta     1140

ccagaaagcg ctgctgtacc tgtgtggtgg agatgactga agcccgacac ggcctgagcg     1200

tccagaaatg gtgctcacca tgcttccagc taacaggtct agaaaaccag cttgcgaata     1260

acagtccccg tggccatccc tgtgagggtg acgttagcat tacccccaac ctcattttag     1320

ttgcctaagc attgcctggc cttcctgtct agtctctcct gtaagccaaa gaaatgaaca     1380

ttccaaggag ttggaagtga agtctatgat gtgaaacact ttgcctcctg tgtactgtgt     1440

cataaacaga tgaataaact gaatttgtac tttagaaaca cgtactttgt ggccctgctt     1500

tcaactgaat tgtttgaaaa ttaaacgtgc ttggggttca gctggtgagg ctgtccctgt     1560

aggaagaaag ctctgggact gagctgtaca gtatggttgc ccctatccaa gtgtcgctat     1620

ttaagttaaa tttaaatgaa ataaaataaa ataaaatcaa aaaaa                     1665


<210>  4872
<211>  1632
<212>  DNA
<213>  homo sapiens

<400>  4872
gctcagcatt tggggacgct ctcagctctc ggcgcacggc ccaggtaagc ggggcgcgcc       60

ctgcccgccc gcgatgggcc gccagctagc ggggtgtgga gacgctggga agaaggcttc      120

cttcaaaatg tctactgttc acgaaatcct gtgcaagctc agcttggagg gtgatcactc      180

tacaccccca agtgcatatg ggtctgtcaa agcctatact aactttgatg ctgagcggga      240

tgctttgaac attgaaacag ccatcaagac caaaggtgtg gatgaggtca ccattgtcaa      300

cattttgacc aaccgcagca atgcacagag acaggatatt gccttcgcct accagagaag      360

gaccaaaaag gaacttgcat cagcactgaa gtcagcctta tctggccacc tggagacggt      420

gattttgggc ctattgaaga cacctgctca gtatgacgct tctgagctaa aagcttccat      480

gaaggggctg ggaaccgacg aggactctct cattgagatc atctgctcca gaaccaacca      540

ggagctgcag gaaattaaca gagtctacaa ggaaatgtac aagactgatc tggagaagga      600

cattatttcg gacacatctg gtgacttccg caagctgatg gttgccctgg caaagggtag      660

aagagcagag gatggctctg tcattgatta tgaactgatt gaccaagatg ctcgggatct      720

ctatgacgct ggagtgaaga ggaaaggaac tgatgttccc aagtggatca gcatcatgac      780

cgagcggagc gtgccccacc tccagaaagt atttgatagg tacaagagtt acagccctta      840

tgacatgttg gaaagcatca ggaaagaggt taaaggagac ctggaaaatg ctttcctgaa      900

cctggttcag tgcattcaga acaagcccct gtattttgct gatcggctgt atgactccat      960

gaagggcaag gggacgcgag ataaggtcct gatcagaatc atggtctccc gcagtgaagt     1020

ggacatgttg aaaattaggt ctgaattcaa gagaaagtac ggcaagtccc tgtactatta     1080

tatccagcaa gacactaagg gcgactacca gaaagcgctg ctgtacctgt gtggtggaga     1140

tgactgaagc ccgacacggc ctgagcgtcc agaaatggtg ctcaccatgc ttccagctaa     1200

caggtctaga aaaccagctt gcgaataaca gtccccgtgg ccatccctgt gagggtgacg     1260

ttagcattac ccccaacctc attttagttg cctaagcatt gcctggcctt cctgtctagt     1320

ctctcctgta agccaaagaa atgaacattc caaggagttg gaagtgaagt ctatgatgtg     1380

aaacactttg cctcctgtgt actgtgtcat aaacagatga ataaactgaa tttgtacttt     1440

agaaacacgt actttgtggc cctgctttca actgaattgt ttgaaaatta aacgtgcttg     1500

gggttcagct ggtgaggctg tccctgtagg aagaaagctc tgggactgag ctgtacagta     1560

tggttgcccc tatccaagtg tcgctattta agttaaattt aaatgaaata aaataaaata     1620

aaatcaaaaa aa                                                         1632


<210>  4873
<211>  1644
<212>  DNA
<213>  homo sapiens

<400>  4873
gctcagcatt tggggacgct ctcagctctc ggcgcacggc ccaggttatc ttgtagcata       60

gcaacttcgg atttcactct acccggagag tttcccgctt ggttgaacac attggcctca      120

ggaagcttcc ttcaaaatgt ctactgttca cgaaatcctg tgcaagctca gcttggaggg      180

tgatcactct acacccccaa gtgcatatgg gtctgtcaaa gcctatacta actttgatgc      240

tgagcgggat gctttgaaca ttgaaacagc catcaagacc aaaggtgtgg atgaggtcac      300

cattgtcaac attttgacca accgcagcaa tgcacagaga caggatattg ccttcgccta      360

ccagagaagg accaaaaagg aacttgcatc agcactgaag tcagccttat ctggccacct      420

ggagacggtg attttgggcc tattgaagac acctgctcag tatgacgctt ctgagctaaa      480

agcttccatg aaggggctgg gaaccgacga ggactctctc attgagatca tctgctccag      540

aaccaaccag gagctgcagg aaattaacag agtctacaag gaaatgtaca agactgatct      600

ggagaaggac attatttcgg acacatctgg tgacttccgc aagctgatgg ttgccctggc      660

aaagggtaga agagcagagg atggctctgt cattgattat gaactgattg accaagatgc      720

tcgggatctc tatgacgctg gagtgaagag gaaaggaact gatgttccca agtggatcag      780

catcatgacc gagcggagcg tgccccacct ccagaaagta tttgataggt acaagagtta      840

cagcccttat gacatgttgg aaagcatcag gaaagaggtt aaaggagacc tggaaaatgc      900

tttcctgaac ctggttcagt gcattcagaa caagcccctg tattttgctg atcggctgta      960

tgactccatg aagggcaagg ggacgcgaga taaggtcctg atcagaatca tggtctcccg     1020

cagtgaagtg gacatgttga aaattaggtc tgaattcaag agaaagtacg gcaagtccct     1080

gtactattat atccagcaag acactaaggg cgactaccag aaagcgctgc tgtacctgtg     1140

tggtggagat gactgaagcc cgacacggcc tgagcgtcca gaaatggtgc tcaccatgct     1200

tccagctaac aggtctagaa aaccagcttg cgaataacag tccccgtggc catccctgtg     1260

agggtgacgt tagcattacc cccaacctca ttttagttgc ctaagcattg cctggccttc     1320

ctgtctagtc tctcctgtaa gccaaagaaa tgaacattcc aaggagttgg aagtgaagtc     1380

tatgatgtga aacactttgc ctcctgtgta ctgtgtcata aacagatgaa taaactgaat     1440

ttgtacttta gaaacacgta ctttgtggcc ctgctttcaa ctgaattgtt tgaaaattaa     1500

acgtgcttgg ggttcagctg gtgaggctgt ccctgtagga agaaagctct gggactgagc     1560

tgtacagtat ggttgcccct atccaagtgt cgctatttaa gttaaattta aatgaaataa     1620

aataaaataa aatcaaaaaa aaaa                                            1644


<210>  4874
<211>  6855
<212>  DNA
<213>  homo sapiens

<400>  4874
ggccggaggg cgcccgaggg gccccgggcc gcggcgctca gggcccgggc ggccggcggc       60

ggccccgggg ctggggggag tccagcccgg atattgagtg cagccattga gaaaagccaa      120

actcttgtgt gtgcgcgtct cgatagcccc caagatggcc gccaatgtgg gatcgatgtt      180

tcaatattgg aagcgatttg atctacggcg actccagaag gagcttaatt ccgtcgcttc      240

tgagctgtct gcacggcagg aggagagtga acattctcat aaacatttaa ttgaactccg      300

ccgggaattt aagaaaaatg tacctgagga aatcagagag atggtggctc ctgtattaaa      360

aagcttccaa gccgaggtgg tggcccttag taagagaagt caggaggcgg aggctgcttt      420

tctgagtgtt tacaagcaat taattgaagc accagacccc gtgcctgtgt ttgaggcggc      480

acgcagccta gacgacagac tgcagccccc cagctttgac cccagtgggc agccccggcg      540

agacctccac acttcgtgga agaggaaccc cgagctcctc agccccaaag agcagagaga      600

ggggacgtcg cctgccgggc ccacgctgac cgagggaagc cgcctcccag gcattcccgg      660

gaaagccctc ctgacagaaa ccttgctgca gagaaatgag gcggaaaaac aaaagggcct      720

tcaagaagta cagatcactt tggcggccag actgggggag gcagaggaga aaatcaaagt      780

cctacattca gcgctaaagg ctacgcaggc agagctgcta gagctgcggc ggaagtacga      840

cgaggaggca gcatccaagg cagatgaagt cggcctgatc atgaccaacc tggagaaagc      900

taatcagcga gctgaggctg cccagcggga ggtggaaagt ctccgggaac agctggcctc      960

tgtcaacagc tccatccgcc tggcttgctg ctctccccag gggcccagtg gggataaggt     1020

gaacttcact ctgtgctcgg gccctcggct ggaggccgcg ctggcctcca aggacaggga     1080

gatcctgcgg ctgctgaagg acgtgcagca cctccagagc tcactgcagg agctggagga     1140

ggcatccgcc aaccagatcg ccgacctgga gcggcagctc acggccaagt ccgaggccat     1200

agaaaagctg gaagagaagc tccaggccca gtctgactat gaggaaatta aaacggagct     1260

gagcatcctg aaagccatga agctggcctc cagcacctgc agcctccccc agggcatggc     1320

caagcctgaa gactcactgc ttattgcaaa ggaggccttc ttccccacgc agaaattcct     1380

tctggagaag cccagcctcc tggccagccc tgaggaagac ccatcagagg acgattccat     1440

caaggattca ctgggcacgg agcagtccta cccctcccct cagcagctcc cacctccacc     1500

agggccagaa gaccccctgt ctcccagccc cgggcagccc ctgctgggcc ccagcttggg     1560

gcctgacggc actcggactt tctcgctgtc ccccttcccc agcctggcat caggggagag     1620

actgatgatg cccccagccg ccttcaaggg agaggcgggc ggcctgctgg tgttcccccc     1680

agccttctat ggcgccaagc cccccacagc ccctgccacc ccggcccctg gccctgagcc     1740

actgggcggt cctgagcccg cggatggtgg tgggggcgga gcggcggggc ccggggcaga     1800

ggaggagcag ctggacacgg cagagatcgc cttccaggtg aaggagcagc tgctgaaaca     1860

caacatcggg cagcgggtgt ttgggcatta cgtgctgggg ctgtcgcagg gctcggtcag     1920

cgagatccta gcccggccca agccctggcg caagctcacg gtgaagggca aggagccctt     1980

catcaagatg aagcagttcc tgtcggatga gcagaatgta ctggcgctca ggaccatcca     2040

agtgcggcag cgaggcagca tcaccccgag aatccgcacg cctgagacag gctcagacga     2100

cgccatcaag agcattctag agcaggccaa gaaggagatc gagtcgcaga agggcggcga     2160

gcccaagacc tcggtggccc cgctgagcat cgccaacggc acgacccccg ccagcacctc     2220

ggaggacgcc atcaagagca tcctggagca ggcacgccgt gagatgcagg cgcaacagca     2280

ggcgctgctg gagatggagg tggcgcccag gggccgctcg gtgcccccct cgcccccgga     2340

gcggccatca ctggccaccg cgagccagaa cggggccccg gccttggtga agcaggagga     2400

gggcagcggg ggccccgcgc aggcgccgct cccggtcctg tcccccgccg ccttcgtgca     2460

gagcatcatc cgcaaggtca agtccgagat cggcgacgcc ggctacttcg accaccactg     2520

ggcctccgac cgcggcctgc tcagccgccc ctacgcctcc gtgtcgccct cgctgtcctc     2580

ctcctcctcc tctggctact ctggccagcc caacggccgc gcctggcccc gcggggacga     2640

ggcccctgtg ccccccgagg acgaggcggc ggcaggggcg gaggacgaac cccccaggac     2700

gggcgagctc aaggctgagg gcgcgacggc cgaggcgggc gcgcggctgc cctactaccc     2760

ggcctacgtg ccgcgcaccc tgaagcccac cgtgccgccg ctgacccccg agcagtacga     2820

gctgtacatg taccgtgagg tagacacgct ggagctcacc cgccaggtca aggagaagct     2880

ggccaagaac ggcatctgcc agaggatctt cggggagaag gtgctgggcc tgtcacaggg     2940

cagcgtgagc gacatgctgt cccggccgaa gccatggagc aagctgacgc agaaggggcg     3000

ggagcccttc atccgcatgc agctgtggct ctctgaccag ctcggccagg cagtgggcca     3060

gcagcctggt gcctcccagg ccagtcccac agaaccaagg tcctcaccat ccccaccccc     3120

cagccccaca gagcctgaga agagctccca ggagccgttg agcctgtccc tggagagcag     3180

caaggagaac cagcagccag agggccgctc cagctcctcg ttgagcggga agatgtactc     3240

aggcagccag gccccagggg gcatccagga gatcgtggcc atgtcccccg agctggacac     3300

gtactccatc accaagaggg tgaaggaggt cctcacagac aacaatctag ggcagcggct     3360

gtttggggaa agcatcctgg gtctgacaca gggctccgtg tctgacctgc tgtcccggcc     3420

caaaccctgg cacaagctga gcctgaaggg gcgggagcct tttgtccgca tgcagctgtg     3480

gctcaatgac ccccataacg tggagaagct gagggatatg aagaagctgg agaagaaagc     3540

ctacctgaaa cgtcgctatg gcctcatcag caccggctca gacagtgagt ccccggccac     3600

ccgctcagag tgccccagcc cctgcctgca gccccaggac ctgagcctcc tgcagatcaa     3660

gaagccccgg gtggtgctgg cacccgagga gaaggaggca ctgcggaagg cctatcagct     3720

ggaaccctac ccctcgcagc agaccatcga gctcctctcc ttccagctca acctcaagac     3780

caacaccgtc atcaactggt tccacaacta caggtcccgg atgcgccggg agatgttggt     3840

ggaggggacc caggatgagc cagaccttga tccaagcggg ggtcctggaa tcctaccgcc     3900

aggccactcc cacccagacc ccaccccgca gagccctgac tctgagactg aggaccagaa     3960

gccaaccgtg aaggaactgg agcttcagga gggccctgag gagaacagca cacccctgac     4020

cacccaggac aaggcccaag tgaggatcaa gcaggaacag atggaggagg atgctgagga     4080

agaggcaggc agccagcccc aggactcagg ggagctggac aaaggccaag gtccccccaa     4140

agaggagcat cccgaccctc cgggtaatga tggactccca aaagtggctc ccgggcccct     4200

ccttccaggt ggatccaccc cagactgtcc ctcacttcat ccccaacagg agagtgaggc     4260

cggggagcga cttcacccgg accctttaag ttttaagtca gcctcagagt cctcacgctg     4320

cagcctggag gtgtcactga actcgccctc ggccgcctcc tcaccaggcc tcatgatgtc     4380

tgtgtcacct gtcccctcct cctcagctcc catctcccca tccccacctg gcgccccccc     4440

tgccaaagtg ccgagtgcca gccccactgc tgacatggct ggagccttgc accccagtgc     4500

caaggtgaac cccaacttgc agcggcggca tgagaagatg gccaatctga acaacatcat     4560

ttaccgagta gagcgggctg ccaatcggga ggaggccctg gagtgggagt tctgaaggca     4620

gggtgagggg gcaagggaca taccctggta actaccttcc ttctcgcact tactctcctc     4680

aacaggatgg ggtaagggag ggaggaactc aaccatcaaa atgtggacag caatgttatg     4740

ccgtttacgt tttttgttgt aatcctagtt ctatgaagct gtgtgagcag gtgggtcaaa     4800

tgccattgcc tccacttttc tgcacccccc tgctcctctt caccctgacc cctctgcagg     4860

aggcagaagc aaaatggcac cacatattca cctgaaaact ccaaactctt ttagaaaaat     4920

aaataaatat ttatagacct cttttagata ttttaataaa ggatcctttg gaatttatcc     4980

cagctgatgc tgttttgata ttacagagag ttataaaatc aggatgctgt cacaactgtt     5040

gcgaagtata cactgaagtt gtgtcgtttt tgccactaga tgagattaaa agaagacaat     5100

tattcaaagc catcacaaaa cactataaga ctgaccaaaa tttagataac ctttgaacca     5160

cgattttttt ccacatctgt ctgtgagaca cagcgcaatg ctactgccct tccagaaact     5220

gtgctaaaaa gagaaagtcc aaaagactct aaacaaaaac ctcgacgccg ttgaggatgt     5280

gtttcattct ggtggtctgt tttgcaagct tgataacaga atgtccgtgc cattgtaaat     5340

gttgtagaga tgtgggccgt ggcccaaccg tcctatatga gatgtagcat ggtacagaac     5400

aaactgctta cacaggtctc actagttaga aacctgtggg ccatggaggt cagacatcca     5460

tcttgtccat ctataggcaa gaagtgtttc cagatccttt ggaaaggtgg gcatggggca     5520

ggtgcttgga gagtggcgtt tgagccagag cgaccccatt tcccgtgtga accataggca     5580

caacccagga agtttcccca cttgtaggag tgtgggtatt ccagagcaag actgtggcca     5640

ccatcttccc ctcttggtgt tttccgaaag tgacagtgtt ggtcatccca tgaccactga     5700

agcttagtaa ccagcgccaa aaagtagatt catcaaacta gagaccccag ctccccttct     5760

cgccatcttc tttctcaagt tgaccgtggt gctgtttctg gaaggcatct gcaactccaa     5820

gtccatgcag aactctggaa ggccaagttc atcgcagcat gttcaccata tcccagcctc     5880

caaatctatc ctcctacctt ccaacgcatg acctgttggg gagcagagac ttaaccccca     5940

actcagagga acccttcctc cagcgtcttt ggcatggttt ctagggtgag agttcccaat     6000

ttggatagaa cggccaccat attggttact gaatctctct cccttgtttt tattacgttt     6060

cctttttcaa actgtccatg ggaaggctga attgagtgac tccccagaat gaagatgaga     6120

aggtgaatat aatcaatgcc aatgtaatgc cagcgggtga gatggccgat ggaggtttca     6180

aagatgtagc tagcattttg aaaccatatg ggcaaaaccc ggcaaccaga aggggacaga     6240

taaggaccgt tccagaaatc ccaactctca cacccagccc aggctgcagt ctccacacca     6300

aacagtcaac aaaacacaaa ccctgaagga aaaccttttc catacaccca ggctatgcat     6360

tgaagagttt tccactgtat acatttttat ccagatgaag gtatttttat attttgacaa     6420

taggaaacag tgaccatttt cagagtaatc aaatctggaa caaatgaaac atcttttagc     6480

caccaccacc ctgttgcaat taagacaacc gtgggggaac acaccacttt ttactgttga     6540

aaccaacaca acgttgaaat ccaggcttat acgcagactc cgattcctag agaactaaat     6600

ttggctttag tgtgacggga tttgattaag cacttagtat agtcttttga acacggaaat     6660

cctgttgtac ttaaagctag cggacccgtg aacaactttg tcaggttcac gtcctataac     6720

ggttaaaaaa cacacacaca catacacaaa ccgtttctat gagagattga tgaactttgt     6780

ttaaaatttt aaaaaaagga acacgttctg taaacgagtc gctaaataca gaattgtata     6840

ataaaaaaaa aaaaa                                                      6855


<210>  4875
<211>  2239
<212>  DNA
<213>  homo sapiens

<400>  4875
ccccggcgca gcgcggccgc agcagcctcc gccccccgca cggtgtgagc gcccgacgcg       60

gccgaggcgg ccggagtccc gagctagccc cggcggccgc cgccgcccag accggacgac      120

aggccacctc gtcggcgtcc gcccgagtcc ccgcctcgcc gccaacgcca caaccaccgc      180

gcacggcccc ctgactccgt ccagtattga tcgggagagc cggagcgagc tcttcgggga      240

gcagcgatgc gaccctccgg gacggccggg gcagcgctcc tggcgctgct ggctgcgctc      300

tgcccggcga gtcgggctct ggaggaaaag aaagtttgcc aaggcacgag taacaagctc      360

acgcagttgg gcacttttga agatcatttt ctcagcctcc agaggatgtt caataactgt      420

gaggtggtcc ttgggaattt ggaaattacc tatgtgcaga ggaattatga tctttccttc      480

ttaaagacca tccaggaggt ggctggttat gtcctcattg ccctcaacac agtggagcga      540

attcctttgg aaaacctgca gatcatcaga ggaaatatgt actacgaaaa ttcctatgcc      600

ttagcagtct tatctaacta tgatgcaaat aaaaccggac tgaaggagct gcccatgaga      660

aatttacagg aaatcctgca tggcgccgtg cggttcagca acaaccctgc cctgtgcaac      720

gtggagagca tccagtggcg ggacatagtc agcagtgact ttctcagcaa catgtcgatg      780

gacttccaga accacctggg cagctgccaa aagtgtgatc caagctgtcc caatgggagc      840

tgctggggtg caggagagga gaactgccag aaactgacca aaatcatctg tgcccagcag      900

tgctccgggc gctgccgtgg caagtccccc agtgactgct gccacaacca gtgtgctgca      960

ggctgcacag gcccccggga gagcgactgc ctggtctgcc gcaaattccg agacgaagcc     1020

acgtgcaagg acacctgccc cccactcatg ctctacaacc ccaccacgta ccagatggat     1080

gtgaaccccg agggcaaata cagctttggt gccacctgcg tgaagaagtg tccccgtaat     1140

tatgtggtga cagatcacgg ctcgtgcgtc cgagcctgtg gggccgacag ctatgagatg     1200

gaggaagacg gcgtccgcaa gtgtaagaag tgcgaagggc cttgccgcaa agtgtgtaac     1260

ggaataggta ttggtgaatt taaagactca ctctccataa atgctacgaa tattaaacac     1320

ttcaaaaact gcacctccat cagtggcgat ctccacatcc tgccggtggc atttaggggt     1380

gactccttca cacatactcc tcctctggat ccacaggaac tggatattct gaaaaccgta     1440

aaggaaatca cagggttttt gctgattcag gcttggcctg aaaacaggac ggacctccat     1500

gcctttgaga acctagaaat catacgcggc aggaccaagc aacatggtca gttttctctt     1560

gcagtcgtca gcctgaacat aacatccttg ggattacgct ccctcaagga gataagtgat     1620

ggagatgtga taatttcagg aaacaaaaat ttgtgctatg caaatacaat aaactggaaa     1680

aaactgtttg ggacctccgg tcagaaaacc aaaattataa gcaacagagg tgaaaacagc     1740

tgcaaggcca caggccaggt ctgccatgcc ttgtgctccc ccgagggctg ctggggcccg     1800

gagcccaggg actgcgtctc ttgccggaat gtcagccgag gcagggaatg cgtggacaag     1860

tgcaaccttc tggagggtga gccaagggag tttgtggaga actctgagtg catacagtgc     1920

cacccagagt gcctgcctca ggccatgaac atcacctgca caggacgggg accagacaac     1980

tgtatccagt gtgcccacta cattgacggc ccccactgcg tcaagacctg cccggcagga     2040

gtcatgggag aaaacaacac cctggtctgg aagtacgcag acgccggcca tgtgtgccac     2100

ctgtgccatc caaactgcac ctacgggtcc taataaatct tcactgtctg actttagtct     2160

cccactaaaa ctgcatttcc tttctacaat ttcaatttct ccctttgctt caaataaagt     2220

cctgacacta ttcatttga                                                  2239


<210>  4876
<211>  1595
<212>  DNA
<213>  homo sapiens

<400>  4876
ccccggcgca gcgcggccgc agcagcctcc gccccccgca cggtgtgagc gcccgacgcg       60

gccgaggcgg ccggagtccc gagctagccc cggcggccgc cgccgcccag accggacgac      120

aggccacctc gtcggcgtcc gcccgagtcc ccgcctcgcc gccaacgcca caaccaccgc      180

gcacggcccc ctgactccgt ccagtattga tcgggagagc cggagcgagc tcttcgggga      240

gcagcgatgc gaccctccgg gacggccggg gcagcgctcc tggcgctgct ggctgcgctc      300

tgcccggcga gtcgggctct ggaggaaaag aaagtttgcc aaggcacgag taacaagctc      360

acgcagttgg gcacttttga agatcatttt ctcagcctcc agaggatgtt caataactgt      420

gaggtggtcc ttgggaattt ggaaattacc tatgtgcaga ggaattatga tctttccttc      480

ttaaagacca tccaggaggt ggctggttat gtcctcattg ccctcaacac agtggagcga      540

attcctttgg aaaacctgca gatcatcaga ggaaatatgt actacgaaaa ttcctatgcc      600

ttagcagtct tatctaacta tgatgcaaat aaaaccggac tgaaggagct gcccatgaga      660

aatttacagg aaatcctgca tggcgccgtg cggttcagca acaaccctgc cctgtgcaac      720

gtggagagca tccagtggcg ggacatagtc agcagtgact ttctcagcaa catgtcgatg      780

gacttccaga accacctggg cagctgccaa aagtgtgatc caagctgtcc caatgggagc      840

tgctggggtg caggagagga gaactgccag aaactgacca aaatcatctg tgcccagcag      900

tgctccgggc gctgccgtgg caagtccccc agtgactgct gccacaacca gtgtgctgca      960

ggctgcacag gcccccggga gagcgactgc ctggtctgcc gcaaattccg agacgaagcc     1020

acgtgcaagg acacctgccc cccactcatg ctctacaacc ccaccacgta ccagatggat     1080

gtgaaccccg agggcaaata cagctttggt gccacctgcg tgaagaagtg tccccgtaat     1140

tatgtggtga cagatcacgg ctcgtgcgtc cgagcctgtg gggccgacag ctatgagatg     1200

gaggaagacg gcgtccgcaa gtgtaagaag tgcgaagggc cttgccgcaa agtgtgtaac     1260

ggaataggta ttggtgaatt taaagactca ctctccataa atgctacgaa tattaaacac     1320

ttcaaaaact gcacctccat cagtggcgat ctccacatcc tgccggtggc atttaggggt     1380

gactccttca cacatactcc tcctctggat ccacaggaac tggatattct gaaaaccgta     1440

aaggaaatca caggtttgag ctgaattatc acatgaatat aaatgggaaa tcagtgtttt     1500

agagagagaa cttttcgaca tatttcctgt tcccttggaa taaaaacatt tcttctgaaa     1560

ttttaccgtt aaaaaaaaaa aaaaaaaaaa aaaaa                                1595


<210>  4877
<211>  2865
<212>  DNA
<213>  homo sapiens

<400>  4877
ccccggcgca gcgcggccgc agcagcctcc gccccccgca cggtgtgagc gcccgacgcg       60

gccgaggcgg ccggagtccc gagctagccc cggcggccgc cgccgcccag accggacgac      120

aggccacctc gtcggcgtcc gcccgagtcc ccgcctcgcc gccaacgcca caaccaccgc      180

gcacggcccc ctgactccgt ccagtattga tcgggagagc cggagcgagc tcttcgggga      240

gcagcgatgc gaccctccgg gacggccggg gcagcgctcc tggcgctgct ggctgcgctc      300

tgcccggcga gtcgggctct ggaggaaaag aaagtttgcc aaggcacgag taacaagctc      360

acgcagttgg gcacttttga agatcatttt ctcagcctcc agaggatgtt caataactgt      420

gaggtggtcc ttgggaattt ggaaattacc tatgtgcaga ggaattatga tctttccttc      480

ttaaagacca tccaggaggt ggctggttat gtcctcattg ccctcaacac agtggagcga      540

attcctttgg aaaacctgca gatcatcaga ggaaatatgt actacgaaaa ttcctatgcc      600

ttagcagtct tatctaacta tgatgcaaat aaaaccggac tgaaggagct gcccatgaga      660

aatttacagg aaatcctgca tggcgccgtg cggttcagca acaaccctgc cctgtgcaac      720

gtggagagca tccagtggcg ggacatagtc agcagtgact ttctcagcaa catgtcgatg      780

gacttccaga accacctggg cagctgccaa aagtgtgatc caagctgtcc caatgggagc      840

tgctggggtg caggagagga gaactgccag aaactgacca aaatcatctg tgcccagcag      900

tgctccgggc gctgccgtgg caagtccccc agtgactgct gccacaacca gtgtgctgca      960

ggctgcacag gcccccggga gagcgactgc ctggtctgcc gcaaattccg agacgaagcc     1020

acgtgcaagg acacctgccc cccactcatg ctctacaacc ccaccacgta ccagatggat     1080

gtgaaccccg agggcaaata cagctttggt gccacctgcg tgaagaagtg tccccgtaat     1140

tatgtggtga cagatcacgg ctcgtgcgtc cgagcctgtg gggccgacag ctatgagatg     1200

gaggaagacg gcgtccgcaa gtgtaagaag tgcgaagggc cttgccgcaa agtgtgtaac     1260

ggaataggta ttggtgaatt taaagactca ctctccataa atgctacgaa tattaaacac     1320

ttcaaaaact gcacctccat cagtggcgat ctccacatcc tgccggtggc atttaggggt     1380

gactccttca cacatactcc tcctctggat ccacaggaac tggatattct gaaaaccgta     1440

aaggaaatca cagggttttt gctgattcag gcttggcctg aaaacaggac ggacctccat     1500

gcctttgaga acctagaaat catacgcggc aggaccaagc aacatggtca gttttctctt     1560

gcagtcgtca gcctgaacat aacatccttg ggattacgct ccctcaagga gataagtgat     1620

ggagatgtga taatttcagg aaacaaaaat ttgtgctatg caaatacaat aaactggaaa     1680

aaactgtttg ggacctccgg tcagaaaacc aaaattataa gcaacagagg tgaaaacagc     1740

tgcaaggcca caggccaggt ctgccatgcc ttgtgctccc ccgagggctg ctggggcccg     1800

gagcccaggg actgcgtctc ttgccggaat gtcagccgag gcagggaatg cgtggacaag     1860

tgcaaccttc tggagggtga gccaagggag tttgtggaga actctgagtg catacagtgc     1920

cacccagagt gcctgcctca ggccatgaac atcacctgca caggacgggg accagacaac     1980

tgtatccagt gtgcccacta cattgacggc ccccactgcg tcaagacctg cccggcagga     2040

gtcatgggag aaaacaacac cctggtctgg aagtacgcag acgccggcca tgtgtgccac     2100

ctgtgccatc caaactgcac ctacgggcca ggaaatgaga gtctcaaagc catgttattc     2160

tgccttttta aactatcatc ctgtaatcaa agtaatgatg gcagcgtgtc ccaccagagc     2220

gggagcccag ctgctcagga gtcatgctta ggatggatcc cttctcttct gccgtcagag     2280

tttcagctgg gttggggtgg atgcagccac ctccatgcct ggccttctgc atctgtgatc     2340

atcacggcct cctcctgcca ctgagcctca tgccttcacg tgtctgttcc ccccgctttt     2400

cctttctgcc acccctgcac gtgggccgcc aggttcccaa gagtatccta cccatttcct     2460

tccttccact ccctttgcca gtgcctctca ccccaactag tagctaacca tcacccccag     2520

gactgacctc ttcctcctcg ctgccagatg attgttcaaa gcacagaatt tgtcagaaac     2580

ctgcagggac tccatgctgc cagccttctc cgtaattagc atggccccag tccatgcttc     2640

tagccttggt tccttctgcc cctctgtttg aaattctaga gccagctgtg ggacaattat     2700

ctgtgtcaaa agccagatgt gaaaacatct caataacaaa ctggctgctt tgttcaatgc     2760

tagaacaacg cctgtcacag agtagaaact caaaaatatt tgctgagtga atgaacaaat     2820

gaataaatgc ataataaata attaaccacc aatccaacat ccaga                     2865


<210>  4878
<211>  5616
<212>  DNA
<213>  homo sapiens

<400>  4878
ccccggcgca gcgcggccgc agcagcctcc gccccccgca cggtgtgagc gcccgacgcg       60

gccgaggcgg ccggagtccc gagctagccc cggcggccgc cgccgcccag accggacgac      120

aggccacctc gtcggcgtcc gcccgagtcc ccgcctcgcc gccaacgcca caaccaccgc      180

gcacggcccc ctgactccgt ccagtattga tcgggagagc cggagcgagc tcttcgggga      240

gcagcgatgc gaccctccgg gacggccggg gcagcgctcc tggcgctgct ggctgcgctc      300

tgcccggcga gtcgggctct ggaggaaaag aaagtttgcc aaggcacgag taacaagctc      360

acgcagttgg gcacttttga agatcatttt ctcagcctcc agaggatgtt caataactgt      420

gaggtggtcc ttgggaattt ggaaattacc tatgtgcaga ggaattatga tctttccttc      480

ttaaagacca tccaggaggt ggctggttat gtcctcattg ccctcaacac agtggagcga      540

attcctttgg aaaacctgca gatcatcaga ggaaatatgt actacgaaaa ttcctatgcc      600

ttagcagtct tatctaacta tgatgcaaat aaaaccggac tgaaggagct gcccatgaga      660

aatttacagg aaatcctgca tggcgccgtg cggttcagca acaaccctgc cctgtgcaac      720

gtggagagca tccagtggcg ggacatagtc agcagtgact ttctcagcaa catgtcgatg      780

gacttccaga accacctggg cagctgccaa aagtgtgatc caagctgtcc caatgggagc      840

tgctggggtg caggagagga gaactgccag aaactgacca aaatcatctg tgcccagcag      900

tgctccgggc gctgccgtgg caagtccccc agtgactgct gccacaacca gtgtgctgca      960

ggctgcacag gcccccggga gagcgactgc ctggtctgcc gcaaattccg agacgaagcc     1020

acgtgcaagg acacctgccc cccactcatg ctctacaacc ccaccacgta ccagatggat     1080

gtgaaccccg agggcaaata cagctttggt gccacctgcg tgaagaagtg tccccgtaat     1140

tatgtggtga cagatcacgg ctcgtgcgtc cgagcctgtg gggccgacag ctatgagatg     1200

gaggaagacg gcgtccgcaa gtgtaagaag tgcgaagggc cttgccgcaa agtgtgtaac     1260

ggaataggta ttggtgaatt taaagactca ctctccataa atgctacgaa tattaaacac     1320

ttcaaaaact gcacctccat cagtggcgat ctccacatcc tgccggtggc atttaggggt     1380

gactccttca cacatactcc tcctctggat ccacaggaac tggatattct gaaaaccgta     1440

aaggaaatca cagggttttt gctgattcag gcttggcctg aaaacaggac ggacctccat     1500

gcctttgaga acctagaaat catacgcggc aggaccaagc aacatggtca gttttctctt     1560

gcagtcgtca gcctgaacat aacatccttg ggattacgct ccctcaagga gataagtgat     1620

ggagatgtga taatttcagg aaacaaaaat ttgtgctatg caaatacaat aaactggaaa     1680

aaactgtttg ggacctccgg tcagaaaacc aaaattataa gcaacagagg tgaaaacagc     1740

tgcaaggcca caggccaggt ctgccatgcc ttgtgctccc ccgagggctg ctggggcccg     1800

gagcccaggg actgcgtctc ttgccggaat gtcagccgag gcagggaatg cgtggacaag     1860

tgcaaccttc tggagggtga gccaagggag tttgtggaga actctgagtg catacagtgc     1920

cacccagagt gcctgcctca ggccatgaac atcacctgca caggacgggg accagacaac     1980

tgtatccagt gtgcccacta cattgacggc ccccactgcg tcaagacctg cccggcagga     2040

gtcatgggag aaaacaacac cctggtctgg aagtacgcag acgccggcca tgtgtgccac     2100

ctgtgccatc caaactgcac ctacggatgc actgggccag gtcttgaagg ctgtccaacg     2160

aatgggccta agatcccgtc catcgccact gggatggtgg gggccctcct cttgctgctg     2220

gtggtggccc tggggatcgg cctcttcatg cgaaggcgcc acatcgttcg gaagcgcacg     2280

ctgcggaggc tgctgcagga gagggagctt gtggagcctc ttacacccag tggagaagct     2340

cccaaccaag ctctcttgag gatcttgaag gaaactgaat tcaaaaagat caaagtgctg     2400

ggctccggtg cgttcggcac ggtgtataag ggactctgga tcccagaagg tgagaaagtt     2460

aaaattcccg tcgctatcaa ggaattaaga gaagcaacat ctccgaaagc caacaaggaa     2520

atcctcgatg aagcctacgt gatggccagc gtggacaacc cccacgtgtg ccgcctgctg     2580

ggcatctgcc tcacctccac cgtgcagctc atcacgcagc tcatgccctt cggctgcctc     2640

ctggactatg tccgggaaca caaagacaat attggctccc agtacctgct caactggtgt     2700

gtgcagatcg caaagggcat gaactacttg gaggaccgtc gcttggtgca ccgcgacctg     2760

gcagccagga acgtactggt gaaaacaccg cagcatgtca agatcacaga ttttgggctg     2820

gccaaactgc tgggtgcgga agagaaagaa taccatgcag aaggaggcaa agtgcctatc     2880

aagtggatgg cattggaatc aattttacac agaatctata cccaccagag tgatgtctgg     2940

agctacgggg tgaccgtttg ggagttgatg acctttggat ccaagccata tgacggaatc     3000

cctgccagcg agatctcctc catcctggag aaaggagaac gcctccctca gccacccata     3060

tgtaccatcg atgtctacat gatcatggtc aagtgctgga tgatagacgc agatagtcgc     3120

ccaaagttcc gtgagttgat catcgaattc tccaaaatgg cccgagaccc ccagcgctac     3180

cttgtcattc agggggatga aagaatgcat ttgccaagtc ctacagactc caacttctac     3240

cgtgccctga tggatgaaga agacatggac gacgtggtgg atgccgacga gtacctcatc     3300

ccacagcagg gcttcttcag cagcccctcc acgtcacgga ctcccctcct gagctctctg     3360

agtgcaacca gcaacaattc caccgtggct tgcattgata gaaatgggct gcaaagctgt     3420

cccatcaagg aagacagctt cttgcagcga tacagctcag accccacagg cgccttgact     3480

gaggacagca tagacgacac cttcctccca gtgcctgaat acataaacca gtccgttccc     3540

aaaaggcccg ctggctctgt gcagaatcct gtctatcaca atcagcctct gaaccccgcg     3600

cccagcagag acccacacta ccaggacccc cacagcactg cagtgggcaa ccccgagtat     3660

ctcaacactg tccagcccac ctgtgtcaac agcacattcg acagccctgc ccactgggcc     3720

cagaaaggca gccaccaaat tagcctggac aaccctgact accagcagga cttctttccc     3780

aaggaagcca agccaaatgg catctttaag ggctccacag ctgaaaatgc agaataccta     3840

agggtcgcgc cacaaagcag tgaatttatt ggagcatgac cacggaggat agtatgagcc     3900

ctaaaaatcc agactctttc gatacccagg accaagccac agcaggtcct ccatcccaac     3960

agccatgccc gcattagctc ttagacccac agactggttt tgcaacgttt acaccgacta     4020

gccaggaagt acttccacct cgggcacatt ttgggaagtt gcattccttt gtcttcaaac     4080

tgtgaagcat ttacagaaac gcatccagca agaatattgt ccctttgagc agaaatttat     4140

ctttcaaaga ggtatatttg aaaaaaaaaa aaagtatatg tgaggatttt tattgattgg     4200

ggatcttgga gtttttcatt gtcgctattg atttttactt caatgggctc ttccaacaag     4260

gaagaagctt gctggtagca cttgctaccc tgagttcatc caggcccaac tgtgagcaag     4320

gagcacaagc cacaagtctt ccagaggatg cttgattcca gtggttctgc ttcaaggctt     4380

ccactgcaaa acactaaaga tccaagaagg ccttcatggc cccagcaggc cggatcggta     4440

ctgtatcaag tcatggcagg tacagtagga taagccactc tgtcccttcc tgggcaaaga     4500

agaaacggag gggatggaat tcttccttag acttactttt gtaaaaatgt ccccacggta     4560

cttactcccc actgatggac cagtggtttc cagtcatgag cgttagactg acttgtttgt     4620

cttccattcc attgttttga aactcagtat gctgcccctg tcttgctgtc atgaaatcag     4680

caagagagga tgacacatca aataataact cggattccag cccacattgg attcatcagc     4740

atttggacca atagcccaca gctgagaatg tggaatacct aaggatagca ccgcttttgt     4800

tctcgcaaaa acgtatctcc taatttgagg ctcagatgaa atgcatcagg tcctttgggg     4860

catagatcag aagactacaa aaatgaagct gctctgaaat ctcctttagc catcacccca     4920

accccccaaa attagtttgt gttacttatg gaagatagtt ttctcctttt acttcacttc     4980

aaaagctttt tactcaaaga gtatatgttc cctccaggtc agctgccccc aaaccccctc     5040

cttacgcttt gtcacacaaa aagtgtctct gccttgagtc atctattcaa gcacttacag     5100

ctctggccac aacagggcat tttacaggtg cgaatgacag tagcattatg agtagtgtgg     5160

aattcaggta gtaaatatga aactagggtt tgaaattgat aatgctttca caacatttgc     5220

agatgtttta gaaggaaaaa agttccttcc taaaataatt tctctacaat tggaagattg     5280

gaagattcag ctagttagga gcccaccttt tttcctaatc tgtgtgtgcc ctgtaacctg     5340

actggttaac agcagtcctt tgtaaacagt gttttaaact ctcctagtca atatccaccc     5400

catccaattt atcaaggaag aaatggttca gaaaatattt tcagcctaca gttatgttca     5460

gtcacacaca catacaaaat gttccttttg cttttaaagt aatttttgac tcccagatca     5520

gtcagagccc ctacagcatt gttaagaaag tatttgattt ttgtctcaat gaaaataaaa     5580

ctatattcat ttccactcta aaaaaaaaaa aaaaaa                               5616


<210>  4879
<211>  8284
<212>  DNA
<213>  homo sapiens

<400>  4879
gggctgtaac cttgaacttt cccagcgcgg tgacacattc tccccgctct ccctcccgcc       60

cgcccgctcg ccctcctgcg ccctcccgcg cccccctccc cgcctttttt gaaaaagcat      120

tttaccacca accaccaccc caatccaacc cacaccgaac cttcgcgcac cccctacacc      180

ccaacaacaa caacaactgc aaaatagaaa acaaatcccc aaacccaggc gaaaagcagc      240

caacaccggc ggcggcggcg gcctcggcaa gcacggccag cgcgctcgga ctgcaagagg      300

gttaaaagtg tagattggat ttcacccctg gaaatctagc acgccgagtg aacttgaatc      360

tttggctatt taaggaggac tgggtttgtt gtgaagttgc ggtgatccag cgcagagccc      420

cgtcctgatt gatcgcatcg cggggctcag atgactgtaa aatgaataga tgaaattctt      480

gcttctcgaa gattttcttg ggcatctccc ggaaagtgcg ttttaaggcg aagtcatgat      540

gtattctccc atctgtctca ctcaggatga atttcaccca ttcatcgagg cacttcttcc      600

acatgtccgt gcaattgcct atacttggtt caacctgcag gctcgaaaac gcaagtactt      660

taaaaagcat gagaagcgaa tgtcaaagga tgaagaaaga gcagtcaaag atgagcttct      720

cagtgaaaag cctgaaatca aacagaagtg ggcatccagg ctccttgcca aactgcgcaa      780

agatattcgc caggagtatc gagaggactt tgtgctcacc gtgactggca agaagcaccc      840

gtgctgtgtc ttatccaatc ccgaccagaa gggtaagatt aggagaatcg actgcctgcg      900

acaggcagac aaagtctggc gtctggatct agtcatggtg atcctgttca aaggcatccc      960

cttggaaagt accgatggag agcggctcat gaaatcccca cattgcacaa acccagcact     1020

ttgtgtccag ccacatcata tcacagtatc agttaaggag cttgatttgt ttttggcata     1080

ctacgtgcag gagcaagatt ctggacaatc aggaagtcca agccacaatg atcctgccaa     1140

gaatcctcca ggttaccttg aggatagttt tgtaaaatct ggagtcttca atgtatcaga     1200

acttgtaaga gtatccagaa cgcccataac ccagggaact ggagtcaact tcccaattgg     1260

agaaatccca agccaaccat actatcatga catgaactcg ggggtcaatc ttcagaggtc     1320

tctgtcttct ccaccaagca gcaaaagacc caaaactata tccatagatg aaaatatgga     1380

accaagtcct acaggagact tttacccctc tccaagttca ccagctgctg gaagtcgaac     1440

atggcacgaa agagatcaag atatgtcttc tccgactact atgaagaagc ctgaaaagcc     1500

attgttcagc tctgcatctc cacaggattc ttccccaaga ctgagcactt tcccccagca     1560

ccaccatccc ggaatacctg gagttgcaca cagtgtcatc tcaactcgaa ctccacctcc     1620

accttcaccg ttgccatttc caacacaagc tatccttcct ccagccccat cgagctactt     1680

ttctcatcca acaatcagat atcctcccca cctgaatcct caggatactc tgaagaacta     1740

tgtaccttct tatgacccat ccagtccaca aaccagccag tcctggtacc tgggctagct     1800

tggttccttt ccaagtgtca aataggacac ccatcttacc ggccaatgtc caaaattacg     1860

gtttgaacat aattggagaa cctttccttc aagcagaaac aagcaactga gggaaaaaga     1920

aacacaacaa tagtttaaga aatttttttt ttaaataaaa aaaaaggaaa agaggaagac     1980

tggacaaaac aacacaaagg cagaaaggaa agaaactgaa gaaagaagat aatagaccag     2040

caattgcagc acttacaatc actaattccc ttaaggttga aactgtaatg acataaaaag     2100

ggtcgatgat atttcactga tggtagatcg cagcccctgc aacgtagcct ttgttacatg     2160

aagtccgctg ggaaatagat gttctgtctc tatgacaata tattttaact gactttctag     2220

atgccttaat atttgcatga taagctagtt ttattggttt agtattcttg ttgtttacgc     2280

atggaatcac tattcctggt tatctcacca acgaaggcta ggaggcggcg tcagaggtgc     2340

tgggtgacag agccatgagc cagccatttt ataagcactc tgatttctaa aagttaaaaa     2400

aaatatatga aatctctgta gcctttagtt atcagtacag atttattaaa tttcggccct     2460

taacccagcc ttttccagtg tgtaacccag tttgaaatct taaaaaaaga aaaaatgaaa     2520

aaaaaaggaa aaaaagaaaa aaggaaaaaa acagtttgaa cacaaaggct ctatggaaga     2580

aatgcctcta tgtaggtgaa gtgttctctc tgcatgcaac agtaaaaatt aatataatat     2640

tttccccaca aaagaaacac ttaacagagg caagtgcaat ttataaattt atatctaaag     2700

gggaatcatg attataagtc cttcagccct tggactctaa attgagggga ttaaaaagaa     2760

tttaaaataa ttttgaacga atttattttc ccctcagttt ttgagggcat taaaaaggca     2820

ttaaatcaag acaaatcatg tgcttgagaa aaataaaatt aatgaaaaca cagcacttat     2880

gttggtttag ctgcagcctc cttggaggta gaatttattt atttaaaatt actggttgca     2940

tcaagaaccc atagggtgta caaaaggttc tataaaatct gcattataga gacaaagagg     3000

caggcaaatc catgtcacaa gggtaaagct tacagtttac aaactgggaa cgccagggtg     3060

taggatataa aaacgcactc ttgagaaaac aaatgtaatc agggtgctga aaacttgcat     3120

ggtgctttca gacattagcc ttgttcaaca aatttcttgt attgacagat ccatagtgtg     3180

catgggcaga cacattttgc ctctatgtct cttaaaattt taattaaaaa tactctttcc     3240

agtaatccta atttgcacga agatataatg tccacattac gtgccttgcc ttgaaatcta     3300

aaaaacaaaa aacaaaaaaa aaaaaacaaa aaaatacaac aaagtgacat cactacactt     3360

gttttgctgc atttattatc attttaaatc tttaccattt ttatgacaaa atattttgta     3420

ctccagacga agaaaaatgt gtgacatcat ggatttttta gacagttata cctttatctc     3480

acatttataa agcatatcat ggctgtgtat agttgccgct taaaaattgt aatcgaccag     3540

caatattttc agtattttgg tgtttttttc tattaacctt tcatgttttt catcttccaa     3600

ttaatatttg ggggggaggg gtttcaaatt tatacgaatt atgcaatacc aagttttgcc     3660

tatgtaggta gtgcttttag ctgtattggt tattataggt aagtacacag atttaaaaaa     3720

aaaataatgt atgctttttt gtttgtttgt ttgttttaat tgaccaaagt gggtactgct     3780

atttttgcag tgtgatgagg tccttttgtg tactgagaga tggacagggg atttttttta     3840

atatacatat atatatattc tggggtgggt gggaggattt ttaacacttt gcagtgtagc     3900

tgtgaagcag tgcaccctga gatgggcctg ggctgcaaag cgactgttct gcctactgtg     3960

acaaacttca acttacacag gttcccctct ctaacttccc acctgggttg caagctgaac     4020

tcattactgg ttttcataac aacacaatag taagaacaag caaacacaac aaattctcct     4080

ggaggcagac ttggcttaaa aaggcagact tggcttggtg atagtttttc ttgaaagttc     4140

cagatccaca gtggagagtg agcctgtctc atatttggca aaaatatttg ttgaaatgtc     4200

cacatagggg atgttggatg tttaacactt ttgagagttt aacacatgaa tattctttct     4260

cctagaaaac acattagacc tgttggaggg agtctcccgt attccttttc tgccactttt     4320

cgtccccatt tcatttcatt aatgatagga tatgatttac ctgtgactta ctacttcaaa     4380

tggatggcag tgcacttgga ttttttttta atatccagaa gattgaacag agggttgcta     4440

ttgttgaatg tatttggact gatagattaa aatcaaagtt caatttttaa ggaacaaaaa     4500

agtaaatcct gttttcattt tatctcccct tttaaaactg agaaccagag cagaagggaa     4560

atatagaatt ttaagcaatt aatcttcctg tggatgaatt aaacccatta gatgctgatg     4620

ggattttttt aaggaatggt accttaacta tatatttgat ttcgtttccc ctgagggcta     4680

gaggctgaat ggaggctggt tttattttgc ctttccctca ccgcccagtc ccattgagtg     4740

tattcattac tagaaggaaa atctttcaga attggtgaca catggtaggc tgtcttaagg     4800

agtcccctgg cccccttccc ctaggccatg gcctaataaa ataaactgtc aattgttctc     4860

acagcatatc atttaataat gaatacttta gaacaatgct tatgggctgg agaattgtat     4920

ttgattagcc cattcagttt gatagcccaa atgctgaaca gcacagcggg atcctagcag     4980

tgcaagttca aaagtaagtc caatcatttc tgtgatactc gccctggtag caaacagatc     5040

atctcagcca agctcttcat gtatctttga cctattaggt gaacaaatga acctcacagg     5100

acacacagta ttttttaaag gcagactcgc tctctttttt gccagtgagc agttctagct     5160

aaccaagtta cacactgtgg gtattcctgc ctgcctcttg aatacaaagg cctagttcaa     5220

gtgttgcttt ttttatttca aatcaatttt ttcttctttc ctttttgaga taaaactatt     5280

aaaagtacta ctatatatat aaaatctcaa atcaactttt cggcctcctc ctcgtgtacc     5340

aggaagtata ttctgacgaa gggccccact tttgcaggtc ttgcacgccc ctcccttacc     5400

cagaactgca gagcttcagg atggcgaagg tcacccaagg gcatgagtag ggagtggtgt     5460

ctccaaccat cagttccgtg gcactgttca gcctttgtgt gctgccctgc cacccaccac     5520

tcacagtgcc tctgaagcgt gttacccctg gagtgacgtg agcatttgag gcttgtctaa     5580

ggaaaaaaat aaaaggcagt gaaggagact gtacataaag acatggcaaa aatcttaatt     5640

atagcaatat agttatcggg taatgttcgg gtgggcagct ccattaaaaa atatgtgaat     5700

gaatctgtga agctgcaagt agcgagaaga gcgaaaggtc ttcttaatga accgcctacc     5760

ttgtagacag taatttgtac actgtatagt tttgttaaga atttttttta aattaaaatt     5820

cccatgtttg taaagctaac tttttaacaa ttataatgga actatatgtt gtttccattt     5880

ttaaagtaaa caagaatatt ccttgtttag agactggact tgagttaaaa ctctccagtc     5940

tcttaagtta tgtattaaaa agaaaatctg tccatgttag gagttatttc acagattcct     6000

gtgcttgaaa agcataggat actaatcctt taaaaaagtg taaatggaga aaagttatat     6060

tttatgaagg ttattttgtt gtatttagta ttggaaaagt tggtttccag agcatttcag     6120

aatgtcgaag caccactgtc tttttattag tatatacggc ctttagcaaa agtttttgtg     6180

attgttacgt gatggtattt aaggttaagt ttcacagagc attcaggata ggcagaaaac     6240

taaaacagtg ctatgtctca cataacgtgt cctcagggag cagaatcttg gatttgtgac     6300

ttgtagcttc ataaggactc aacgaaagag attgcacagg gacatcttca gcggtgtgac     6360

agcaggacat gttctttacc tagattcaaa ttctatgtac tgtgtgaaat gatgaaggct     6420

gcagaaagtt atcccatatt cagtgtacag tattcatttt taatgaaaca actctacaat     6480

attgctggca gataggcccc aagcatgaca ttcaatatag tttacatgtt cctgtcaagg     6540

tcttttgtta acattaacca gctgcatgct ttctggactt taagaaattg ggtttctata     6600

gaaaactttt tttttttttt tttttttaat gtgcaggcta ttcaagttca atagtaaaag     6660

ctcaaaaatg aatgttctac tccatgctga aggagctgaa agctgccttc ttcatatttt     6720

gcactttctg gtagttcccc tgttttttct aattccctaa aattgtgtgg gtggagtgga     6780

gccctgcagt tggggggtaa catggaccac tgattttgcc ctttgaccct gcacaatgac     6840

ctttgcatca gccaaactca ttgccatgac aactctttgt actgtgtccg tgccacagat     6900

ctgttggtca cattgttaat agtaaagggg acaagttgga gacggtcaat ttttacattt     6960

tttgttgcaa ttttttcttc aatggttgta agtagttttt tttttttttt aataataaaa     7020

gggttcacta gttaatactc tagaaatatc tgtgtgttgc aattcaaatg tatgttgaga     7080

ttgtgaaaag cgcttcagtg ccactagctt accggtacac tagactaagc ccttgatgac     7140

ttattgcatg atacagtacc aggaacaaca ggtggcctaa atacatgaaa agcagtgtaa     7200

gctagtgaca ctaaagccag tcttgtatta ctgtattttt gacagaatgg ttttgaaaac     7260

tgtgctacag ggactgatgt ggcaaatata tctctttatg cagaaggaag tctttttttt     7320

tctttttttt ttttttaaga agtatggctt tttatgcatc cttcatcgag ggcattgaag     7380

ttgcatggac tgataaaagt tgatgcaaaa caagaaagaa acaaacaaaa aaaaaaaacc     7440

agcaaaatgt ttaccaaaaa actcaaacaa atgagcagtg cctgttcaat ttcacagtct     7500

ctgttgagtt cagttgtaaa tatgtttcaa atgacatttt cttgggaaaa aaaatctcta     7560

caacattgta gaatgtgagg ggtaactaca tcccaggcat aggtttctca aagctgcagt     7620

agattatgtc ttcatcaagc tgttaatttg tgcttatatc atatagaact tttagcatcc     7680

tgggaagagc tgcccccacc tcaatgatat ttctctgaga acaacttttg taggactgtg     7740

tgtttcttta gatacattta gtacaactgt aggtgacgag tagtcagtta ttgcttgcta     7800

gctacacacc agggttgatc cattttaaaa cttttggcat tttgtcctca tgggccataa     7860

atacagaacc ttgtatttta attaaatttt tttacaaaag gaggcacatg cacaatctcc     7920

atgtaacaaa cctttagcag taggatgtat tatacgacag ttacttaatt tctagagttc     7980

aggcctctgg gatcaacccc agactgggcc agaatgttag tgaaggtttt attgtgcccg     8040

gttggaggat aacgttcttt gggtactttt tgtgggttgc aaatgaactc aattgccaca     8100

agttttaaac tggtgtaaat caagcttgac ttaatgtgat tgttactgtt atatccagcc     8160

tatactgcta gcagctgctc atactgcagt caattactgg aagcggatat atttcctatg     8220

caaaaactgt ttaaacaata aaatgagcta tgctacagac tctgaaaaaa aaaaaaaaaa     8280

aaaa                                                                  8284


<210>  4880
<211>  1135
<212>  DNA
<213>  homo sapiens

<400>  4880
gggcagaggg aataagaggc tgcctctgcc caccagtcct gccgcccagg acccgcagca       60

gagacgacgc ctgcagcaag gagaccagga aggggtgaga caaggaagag gatgtctgag      120

ctggagaagg ccatggtggc cctcatcgac gttttccacc aatattctgg aagggaggga      180

gacaagcaca agctgaagaa atccgaactg aaggagctca tcaacaatga gctttcccat      240

ttcttagagg aaatcaaaga gcaggaggtt gtggacaaag tcatggaaac actggacaat      300

gatggagacg gcgaatgtga cttccaggaa ttcatggcct ttgttgccat ggttactact      360

gcctgccacg agttctttga acatgagtga gattagaaag cagccaaacc tttcctgtaa      420

cagagacggt catgcaagaa agcagacagc aagggcttgc agcctagtag gagctgagct      480

ttccagccgt gttgtagcta attaggaagc ttgatttgct ttgtgattga aaaattgaaa      540

acctctttcc aaaggctgtt ttaacggcct gcatcattct ttctgctata ttaggcctgt      600

gtgtaagctg actggcccca gggactcttg ttaacagtaa cttaggagtc aggtctcagt      660

gataaagcgt gcaccgtgca gcccgccatg gccgtgtaga ccctaacccg gagggaaccc      720

tgactacaga aattaccccg gggcaccctt aaaacttcca ctacctttaa aaaacaaagc      780

cttatccagc attatttgaa aacactgctg ttctttaaat gcgttcctca tccatgcaga      840

taacagctgg ttggccggtg tggccctgca agggcgtggt ggcttcggcc tgcttcccgg      900

gatgcgcctg atcaccaggt gaacgctcag cgctggcagc gctcctggaa aaagcaactc      960

catcagaact cgcaatccga gccagctctg ggggctccag cgtggcctcc gtgacccatg     1020

cgattcaagt cgcggctgca ggatccttgc ctccaacgtg cctccagcac atgcggcttc     1080

cgagggcact accgggggct ctgagccacc gcgagggcct gcgttcaata aaaag          1135


<210>  4881
<211>  4108
<212>  DNA
<213>  homo sapiens

<400>  4881
ccggccgtct atgctccagg ccctctcctc gcggtgccgg tgaacccgcc agccgccccg       60

atgtacagca tgatgatgga gaccgacctg cactcgcccg gcggcgccca ggcccccacg      120

aacctctcgg gccccgccgg ggcgggcggc ggcgggggcg gaggcggggg cggcggcggc      180

ggcgggggcg ccaaggccaa ccaggaccgg gtcaaacggc ccatgaacgc cttcatggtg      240

tggtcccgcg ggcagcggcg caagatggcc caggagaacc ccaagatgca caactcggag      300

atcagcaagc gcctgggggc cgagtggaag gtcatgtccg aggccgagaa gcggccgttc      360

atcgacgagg ccaagcggct gcgcgcgctg cacatgaagg agcacccgga ttacaagtac      420

cggccgcgcc gcaagaccaa gacgctgctc aagaaggaca agtactcgct ggccggcggg      480

ctcctggcgg ccggcgcggg tggcggcggc gcggctgtgg ccatgggcgt gggcgtgggc      540

gtgggcgcgg cggccgtggg ccagcgcctg gagagcccag gcggcgcggc gggcggcggc      600

tacgcgcacg tcaacggctg ggccaacggc gcctaccccg gctcggtggc ggcggcggcg      660

gcggccgcgg ccatgatgca ggaggcgcag ctggcctacg ggcagcaccc gggcgcgggc      720

ggcgcgcacc cgcacgcgca ccccgcgcac ccgcacccgc accacccgca cgcgcacccg      780

cacaacccgc agcccatgca ccgctacgac atgggcgcgc tgcagtacag ccccatctcc      840

aactcgcagg gctacatgag cgcgtcgccc tcgggctacg gcggcctccc ctacggcgcc      900

gcggccgccg ccgccgccgc tgcgggcggc gcgcaccaga actcggccgt ggcggcggcg      960

gcggcggcgg cggccgcgtc gtcgggcgcc ctgggcgcgc tgggctctct ggtgaagtcg     1020

gagcccagcg gcagcccgcc cgccccagcg cactcgcggg cgccgtgccc cggggacctg     1080

cgcgagatga tcagcatgta cttgcccgcc ggcgaggggg gcgacccggc ggcggcagca     1140

gcggccgcgg cgcagagccg gctgcactcg ctgccgcagc actaccaggg cgcgggcgcg     1200

ggcgtgaacg gcacggtgcc cctgacgcac atctagcgcc ttcgggacgc cggggactct     1260

gcggcggcga cccacgagct cgcggcccgc gcccggctcc cgccccgccc cggcgcggcg     1320

tggcttttgt acagacgttc ccacattctt gtcaaaagga aaatactgga gacgaacgcc     1380

gggtgacgcg tgtcccccac tcaccttccc cggagaccct ggcgaccgcc gggcgctgac     1440

accagacttg ggttttagac tgaacttcgg tgttttcttg agactttttg tacagtattt     1500

atcacctacg gaggaagcgg aaagcgtttt ctttgctcga ggggacaaaa aagtcaaaac     1560

gaggcgagag gcgaagccca cttttgtata ccggccggcg cgctcacttt cctccgcgtt     1620

gcttccggac ggcgccgacc gccggagccc aagtgacgcg gagctcgtcg catttgttat     1680

aaatgtagta aggcaggtcc aagcacttac aagttttttg tagttgttac cgctcttttg     1740

ggttggtttg ttaatttata caaagagatt accaccacca ccccctcctt cagacggcgg     1800

agttatattc tgggttttgt aaaactttat gtatctgagc atttccattt ttttttttgg     1860

gttttgtatt atttcttgta aatgcattgt gaaaaatttt attttcggcg ttgcaatgcg     1920

gggaggagaa gtcagattat gtacatagtt ttctaaaaag cctttcttct aaaaacgaaa     1980

aaagaccccc cacccaaaat gtttcgagtc aacaaattta agagacagag cccattttct     2040

ccataaattt gtaacatgct atttttatgt gcatgtttta tgagttcaaa atgcaatgag     2100

gaaatctgac agggaaatta tctgtatgaa ctaaaagtaa gggaaccccg gggaatggga     2160

ggacaggatt tttcaaggaa cctttttcaa tgaaagagaa ggaagttaaa acctataggt     2220

tattttgtag agctgagtgt taatacgggc cgagaaataa aagtatcttc tgctccggct     2280

gtttcactgc ggacggctgg ggctgctgcg cgttaccttg ctgcaagcgg ggcgccttcc     2340

acctggctgg gggtctgcgc cacagtttgg tccagaggag ggaggaggaa gggaagaccc     2400

cagtggtggg accctggacc aggccatgga tgaaggacaa agaccagggc aggtcacggg     2460

tttcccaatt ccccagcaat taagatttcg agcagaattt atctaaatgt gtttcaagga     2520

aacacaatcg ctgaaccaaa acgtactgca gccgagcccc ctccgtccat cctctgcccc     2580

tccccctggc ttctttctct tgggaaaacg ggcaaaataa ttgtgctgga ttctcacaca     2640

cacagaaata tcgaccatca ccctcccccg cgtgaactgg gatgcaagtt gctaaccgat     2700

gtgaacgcaa aatgccttgt tcattattcc tgacgagatc ttgaggttgt ttgatgcttt     2760

aaatttttta attatattat tttctaggtg tttattggta cattgcagtt ttttttttga     2820

aatttaaaaa tttctgtaaa actttgtctt caagtaatct gacagcatta aatattgcat     2880

ttaaaaatta tactgtagca aatacattta aaaattaatc acaacgttaa gatgaaatta     2940

tatttttgga aaaaaaaaac acttgaagcc cagatggaaa tacgtttatt tcagcagcct     3000

taggtttccc ctcgctttct caacaccctt ccttgtcctg gagtatggac tgtccgtcca     3060

aaagtgagcc tatgctataa gtttaatgag aaccgaattc agcctgcatt cgagaatagc     3120

tttaagtata atgctgatct gacaattgac gtgtaatttg ggaagtcatt ttgataattt     3180

tgcttaaacc actcattcgt taaagtgatt acaaaaaagt tcaagaatga tgtccactgc     3240

tttctaacaa gataataaac cccccccctc ttttcttttt ctttattttt atttctttta     3300

gctatttgat cctttctgaa gcagttgttt ctggaagagt ctgtgcgccc atggatggct     3360

gagcaccact acgacttagt ccgggataag ggcctcccca gtcctctccg ggagatgatt     3420

tgggaaattt tataatgctt gttctgttaa ctcaccggga ccttgagggt ccaatgggac     3480

cttgagggtt ttctctgaaa tatacaaact taaaggactc tctctgaggt tctttgactg     3540

acgtccactc tcagtctggc ccctgtgctc ccctgtgtgt accctggagt ttctgtgtcc     3600

aattgttggc atctaggtct tggctcaaga ttaggatgtg ggccccactt tagaggcaca     3660

gactatgaaa agctgagtta gtgcgcccgg gacgccaggc aagcagcttt tacagtttgg     3720

catcttattg caggtgcttc gtgcacagtc agctgaaata gccaatgcca ggtgctccaa     3780

ccaccttatt tccttgtttt gttgattaga acaacacaga aaaaagcaaa tataaatttt     3840

taatgactcc atttaaaaat atcacagggt gggggcaagg aaattagctg agattcatct     3900

caggattgag attctatccc cccttccccg cccccagcag tgtcgctcca attcaaatta     3960

gtggagaaaa gattacagta ggccctgagc cgactgtgaa ttcggtgctt ggccaaggta     4020

acactcatcg tattcacgga gtgaaatact atatgatgat agttattata ttatatgacg     4080

acttcattca cttcccaaat cacagggt                                        4108


<210>  4882
<211>  2520
<212>  DNA
<213>  homo sapiens

<400>  4882
ggatggttgt ctattaactt gttcaaaaaa gtatcaggag ttgtcaaggc agagaagaga       60

gtgtttgcaa aagggggaaa gtagtttgct gcctctttaa gactaggact gagagaaaga      120

agaggagaga gaaagaaagg gagagaagtt tgagccccag gcttaagcct ttccaaaaaa      180

taataataac aatcatcggc ggcggcagga tcggccagag gaggagggaa gcgctttttt      240

tgatcctgat tccagtttgc ctctctcttt ttttccccca aattattctt cgcctgattt      300

tcctcgcgga gccctgcgct cccgacaccc ccgcccgcct cccctcctcc tctccccccg      360

cccgcgggcc ccccaaagtc ccggccgggc cgagggtcgg cggccgccgg cgggccgggc      420

ccgcgcacag cgcccgcatg tacaacatga tggagacgga gctgaagccg ccgggcccgc      480

agcaaacttc ggggggcggc ggcggcaact ccaccgcggc ggcggccggc ggcaaccaga      540

aaaacagccc ggaccgcgtc aagcggccca tgaatgcctt catggtgtgg tcccgcgggc      600

agcggcgcaa gatggcccag gagaacccca agatgcacaa ctcggagatc agcaagcgcc      660

tgggcgccga gtggaaactt ttgtcggaga cggagaagcg gccgttcatc gacgaggcta      720

agcggctgcg agcgctgcac atgaaggagc acccggatta taaataccgg ccccggcgga      780

aaaccaagac gctcatgaag aaggataagt acacgctgcc cggcgggctg ctggcccccg      840

gcggcaatag catggcgagc ggggtcgggg tgggcgccgg cctgggcgcg ggcgtgaacc      900

agcgcatgga cagttacgcg cacatgaacg gctggagcaa cggcagctac agcatgatgc      960

aggaccagct gggctacccg cagcacccgg gcctcaatgc gcacggcgca gcgcagatgc     1020

agcccatgca ccgctacgac gtgagcgccc tgcagtacaa ctccatgacc agctcgcaga     1080

cctacatgaa cggctcgccc acctacagca tgtcctactc gcagcagggc acccctggca     1140

tggctcttgg ctccatgggt tcggtggtca agtccgaggc cagctccagc ccccctgtgg     1200

ttacctcttc ctcccactcc agggcgccct gccaggccgg ggacctccgg gacatgatca     1260

gcatgtatct ccccggcgcc gaggtgccgg aacccgccgc ccccagcaga cttcacatgt     1320

cccagcacta ccagagcggc ccggtgcccg gcacggccat taacggcaca ctgcccctct     1380

cacacatgtg agggccggac agcgaactgg aggggggaga aattttcaaa gaaaaacgag     1440

ggaaatggga ggggtgcaaa agaggagagt aagaaacagc atggagaaaa cccggtacgc     1500

tcaaaaagaa aaaggaaaaa aaaaaatccc atcacccaca gcaaatgaca gctgcaaaag     1560

agaacaccaa tcccatccac actcacgcaa aaaccgcgat gccgacaaga aaacttttat     1620

gagagagatc ctggacttct ttttggggga ctatttttgt acagagaaaa cctggggagg     1680

gtggggaggg cgggggaatg gaccttgtat agatctggag gaaagaaagc tacgaaaaac     1740

tttttaaaag ttctagtggt acggtaggag ctttgcagga agtttgcaaa agtctttacc     1800

aataatattt agagctagtc tccaagcgac gaaaaaaatg ttttaatatt tgcaagcaac     1860

ttttgtacag tatttatcga gataaacatg gcaatcaaaa tgtccattgt ttataagctg     1920

agaatttgcc aatatttttc aaggagaggc ttcttgctga attttgattc tgcagctgaa     1980

atttaggaca gttgcaaacg tgaaaagaag aaaattattc aaatttggac attttaattg     2040

tttaaaaatt gtacaaaagg aaaaaattag aataagtact ggcgaaccat ctctgtggtc     2100

ttgtttaaaa agggcaaaag ttttagactg tactaaattt tataacttac tgttaaaagc     2160

aaaaatggcc atgcaggttg acaccgttgg taatttataa tagcttttgt tcgatcccaa     2220

ctttccattt tgttcagata aaaaaaacca tgaaattact gtgtttgaaa tattttctta     2280

tggtttgtaa tatttctgta aatttattgt gatattttaa ggttttcccc cctttatttt     2340

ccgtagttgt attttaaaag attcggctct gtattatttg aatcagtctg ccgagaatcc     2400

atgtatatat ttgaactaat atcatcctta taacaggtac attttcaact taagttttta     2460

ctccattatg cacagtttga gataaataaa tttttgaaat atggacactg aaaaaaaaaa     2520


<210>  4883
<211>  4053
<212>  DNA
<213>  homo sapiens

<400>  4883
gctttatttt tcaattcttc ctagtcccgg ttttgcattt ctaatgacag tgaactgaca       60

aagcgtgaaa gtggtctaag gagcaaaaca aagccagcaa gcctgcttct ggtgtgccaa      120

gattaatcaa tattccagaa acctcggggt ttccccctcc tccctgtgcg gtttccattc      180

cccactcctc ctttcccggg cacagactcc tccccttttc ttaagttgcc ctgatagtaa      240

cttgcagttt cagagcacat gcacactgtc agggctagcc tgcctgctta cgcgcgctgc      300

ggattgttgc tccgttgtac ctgctgggga attcacctcg ttactgcttg atatcttcca      360

ccccttacaa aatcagaaaa gttgtgtttt ctaataccaa agaggaggtt tggctttctg      420

tgggtgattc ccagacactg aagtgcaaag aagagaccct cctagaaaag taaaatatga      480

ctaaaagcaa tggagaagag cccaagatgg ggggcaggat ggagagattc cagcagggag      540

tccgtaaacg cacacttttg gccaagaaga aagtgcagaa cattacaaag gaggatgtta      600

aaagttacct gtttcggaat gcttttgtgc tgctcacagt caccgctgtc attgtgggta      660

caatccttgg atttaccctc cgaccataca gaatgagcta ccgggaagtc aagtacttct      720

cctttcctgg ggaacttctg atgaggatgt tacagatgct ggtcttacca cttatcatct      780

ccagtcttgt cacaggaatg gcggcgctag atagtaaggc atcagggaag atgggaatgc      840

gagctgtagt ctattatatg actaccacca tcattgctgt ggtgattggc ataatcattg      900

tcatcatcat ccatcctggg aagggcacaa aggaaaacat gcacagagaa ggcaaaattg      960

tacgagtgac agctgcagat gccttcctgg acttgatcag gaacatgttc cctccaaatc     1020

tggtagaagc ctgctttaaa cagtttaaaa ccaactatga gaagagaagc tttaaagtgc     1080

ccatccaggc caacgaaacg cttgtgggtg ctgtgataaa caatgtgtct gaggccatgg     1140

agactcttac ccgaatcaca gaggagctgg tcccagttcc aggatctgtg aatggagtca     1200

atgccctggg tctagttgtc ttctccatgt gcttcggttt tgtgattgga aacatgaagg     1260

aacaggggca ggccctgaga gagttctttg attctcttaa cgaagccatc atgagactgg     1320

tagcagtaat aatgtggtat gcccccgtgg gtattctctt cctgattgct gggaagattg     1380

tggagatgga agacatgggt gtgattgggg ggcagcttgc catgtacacc gtgactgtca     1440

ttgttggctt actcattcac gcagtcatcg tcttgccact cctctacttc ttggtaacac     1500

ggaaaaaccc ttgggttttt attggagggt tgctgcaagc actcatcacc gctctgggga     1560

cctcttcaag ttctgccacc ctacccatca ccttcaagtg cctggaagag aacaatggcg     1620

tggacaagcg cgtcaccaga ttcgtgctcc ccgtaggagc caccattaac atggatggga     1680

ctgccctcta tgaggctttg gctgccattt tcattgctca agttaacaac tttgaactga     1740

acttcggaca aattattaca atcagggatc gcctccggac caccaccaac gtactgggag     1800

actccctggg agctgggatt gtggagcact tgtcacgaca tgaactgaag aacagagatg     1860

ttgaaatggg taactcagtg attgaagaga atgaaatgaa gaaaccatat caactgattg     1920

cacaggacaa tgaaactgag aaacccatcg acagtgaaac caagatgtag actaacataa     1980

agaaacactt tcttgagcac caggtgttaa aaaccattat aaaatctttc catctcatta     2040

cagctcattc gctccagcaa gcccgtcatc ttccctttcc tcccttctga taagactgga     2100

aaatagtcct ccaaaacaca agggaggatt ttgggtggcc aaagtgtaca attttcatcc     2160

cacaattgaa atttttaaat catttcatgt tagtcttacc gaataaggta ccaagatcac     2220

aaatagtgtt gatcagatct tacaagttta tgtggcacac aatcctataa atgtgatttt     2280

tttatataag ttaaagagac aaatagtagg ctaaaaacat tttaaaatca acttttgaaa     2340

tttaaaaatc tttcagaata caattcagtt ttagtttcaa aatgttaaca acttgaatta     2400

caaccggtta tcagttggac agtaagattt tatccctttc tcttctgact ggtataccta     2460

tttcattagt agctaggtgc acatatacat ctagcacagc tgtgaggaca gacagaaggc     2520

aaagtttcca tgtggccttg agcaagtccc atctcacctc taggcctcag tgtcctcatc     2580

tataaaatga gggacttccc tagaagtctt catggtctct tccagcccag acatcctgtg     2640

atgtcatgaa agcacctgcc ctctgtttcc cctcagaaca ccctgtacca tccatggagc     2700

acgaggcctt cagaaaagac acttcaatgg gagtgaacat ttctaactaa ggacaggatg     2760

gctgtgtgtg gtggtcacca ggtcctgtga gcaaagtgca ggttatgcaa gtcgccaggc     2820

aggaggccat tccaggagtg ggattattca tcaaactctt tgcccagttc atcccaatgg     2880

gggaagtatt cccttctttc ctactctggg aagaatgtct cctgccactc ctcaactgat     2940

gatagacttc gaaaacagat gagaagacta gcagctagca agggtgcttg tggtcacact     3000

gtggaacact aaagagctag gaaagagttg agcacaggca acattacaaa caaaggattt     3060

gaaaacacca agagtacagg tcttctttaa ggaagaataa aaaagaagag gttcattttt     3120

ctggcttttt ttttcacctg aaacactttt tctcgagtcc aaaatcattc cccccgtgaa     3180

gtctgcttac caaaacataa gacgacttat atatttgaaa gaagtcaaat gaatgagctc     3240

tctaatagaa gtccatgagt tgagtgggta tttcttattt gaaagtgttt ttctttaatc     3300

aaaagtcctt agaatgaggg aaacaaaata tttatttgtt ttggaatccc acttatcaaa     3360

tcattcaaaa ctttcagctg gagtggggtt tgcttttgtt ttgtttgtgt ccataagaga     3420

aatggtagaa gatgaatcag tatgaagaca ctgtcaatga ggttatgaga aaaaaacagc     3480

aggggcatta gtttcaggca aggcagctcc caggtttaga gattaatttt taccccctaa     3540

ggaatatcca gtcaaagacg ctgagtggga gctgtcaggc agtagcagct gtgtttgagt     3600

ttctggctga aaatggtgaa gaatggactt aattatgcta acaaactgaa aaatctagac     3660

atagatcctc tgatatacaa ttagagatat ttttatatag accccaagca ttctgtgcat     3720

aaaagttaac attaggctgt ggtgcagtaa ccatttaatg tcgaggctct atttcggaaa     3780

tacactacaa atgttaaagt acgtggctgt cctcttaaga cactagtaga gcaaagactt     3840

aatcatatca acttaattct gttacacaat atgtgttttt taatatacta accatttctt     3900

atggaaaggt cctgtgggga gcccatcctc tcgccaagcc atcacaggct ctgcatacac     3960

atgcactcag tgtggactgg gaagcattac tttgtagatg tattttcaat aaagaaaaaa     4020

atagttttac attaaaaaaa aaaaaaaaaa aaa                                  4053


<210>  4884
<211>  1377
<212>  DNA
<213>  homo sapiens

<400>  4884
gctttatttt tcaattcttc ctagtcccgg ttttgcattt ctaatgacag tgaactgaca       60

aagcgtgaaa gtggtctaag gagcaaaaca aagccagcaa gcctgcttct ggtgtgccaa      120

gattaatcaa tattccagaa acctcggggt ttccccctcc tccctgtgcg gtttccattc      180

cccactcctc ctttcccggg cacagactcc tccccttttc ttaagttgcc ctgatagtaa      240

cttgcagttt cagagcacat gcacactgtc agggctagcc tgcctgctta cgcgcgctgc      300

ggattgttgc tccgttgtac ctgctgggga attcacctcg ttactgcttg atatcttcca      360

ccccttacaa aatcagaaaa gttgtgtttt ctaataccaa agaggaggtt tggctttctg      420

tgggtgattc ccagacactg aagtgcaaag aagagaccct cctagaaaag taaaatatga      480

ctaaaagcaa tggagaagag cccaagatgg ggggcaggat ggagagattc cagcagggag      540

tccgtaaacg cacacttttg gccaagaaga aagtgcagaa cattacaaag gaggatgtta      600

aaagttacct gtttcggaat gcttttgtgc tgctcacagt caccgctgtc attgtgggtg      660

agtcatttga ttaaaaacaa aaaaacctgt atcttgtttc tctggggcat ctggctgccc      720

ggggaatatt atcagatgaa ctagttgtag gtatcaaaat ggtagcctag gctttcctct      780

gaacttgatg atttttctcc ataaaaatga ctgttttggc ttgtttggag caatatatag      840

taaacacatc attaggcatc attaggcatt atgcaaatca attgtgtgag gaagaaaaat      900

aaataaaata ttttcccatt tcatgtaagg ataaggaagt gatcatttaa tcattaggca      960

tgacaaagca agcatgctag atttggccaa aatgtaatta tatacaatgt cagttgcact     1020

taaaactaat ttatacaatt agtacaccta aaatgacatg ttggttccaa atagtaatta     1080

tattctaact ggtgctgact tgaagctgag tatcaacgct taggcacaga gaccgaatat     1140

tttatgtgtt tgcactctct cacccagcaa ctgggaaagg tagattgggg aaaatgttaa     1200

cacagatctc tttcattcat tgctttgcag agcctgccat aaccagctat accttttttt     1260

gaatcatttc catctcttac taatttagca gggttgacag caatctgtac taataaaata     1320

ttattgtttt gttttgttta ttgatcttaa aaaaaaaaaa aaaaaaaaaa aaaaaaa        1377


<210>  4885
<211>  4188
<212>  DNA
<213>  homo sapiens

<400>  4885
gctttatttt tcaattcttc ctagtcccgg ttttgcattt ctaatgacag tgaactgaca       60

aagcgtgaaa gtggtctaag gagcaaaaca aagccagcaa gcctgcttct ggtgtgccaa      120

gattaatcaa tattccagaa acctcggggt ttccccctcc tccctgtgcg gtttccattc      180

cccactcctc ctttcccggg cacagactcc tccccttttc ttaagttgcc ctgatagtaa      240

cttgcagttt cagagcacat gcacactgtc agggctagcc tgcctgctta cgcgcgctgc      300

ggattgttgc tccgttgtac ctgctgggga attcacctcg ttactgcttg atatcttcca      360

ccccttacaa aatcagaaaa gttgtgtttt ctaataccaa agaggaggtt tggctttctg      420

tgggtgattc ccagacactg aagtgcaaag aagagaccct cctagaaaag taaaatatga      480

ctaaaagcaa tggagaagag cccaagatgg ggggcaggat ggagagattc cagcagggag      540

tccgtaaacg cacacttttg gccaagaaga aagtgcagaa cattacaaag gaggatgtta      600

aaagttacct gtttcggaat gcttttgtgc tgctcacagt caccgctgtc attgtgggta      660

caatccttgg atttaccctc cgaccataca gaatgagcta ccgggaagtc aagtacttct      720

cctttcctgg ggaacttctg atgaggatgt tacagatgct ggtcttacca cttatcatct      780

ccagtcttgt cacaggaatg gcggcgctag atagtaaggc atcagggaag atgggaatgc      840

gagctgtagt ctattatatg actaccacca tcattgctgt ggtgattggc ataatcattg      900

tcatcatcat ccatcctggg aagggcacaa aggaaaacat gcacagagaa ggcaaaattg      960

tacgagtgac agctgcagat gccttcctgg acttgatcag gaacatgttc cctccaaatc     1020

tggtagaagc ctgctttaaa cagtttaaaa ccaactatga gaagagaagc tttaaagtgc     1080

ccatccaggc caacgaaacg cttgtgggtg ctgtgataaa caatgtgtct gaggccatgg     1140

agactcttac ccgaatcaca gaggagctgg tcccagttcc aggatctgtg aatggagtca     1200

atgccctggg tctagttgtc ttctccatgt gcttcggttt tgtgattgga aacatgaagg     1260

aacaggggca ggccctgaga gagttctttg attctcttaa cgaagccatc atgagactgg     1320

tagcagtaat aatgtggtat gcccccgtgg gtattctctt cctgattgct gggaagattg     1380

tggagatgga agacatgggt gtgattgggg ggcagcttgc catgtacacc gtgactgtca     1440

ttgttggctt actcattcac gcagtcatcg tcttgccact cctctacttc ttggtaacac     1500

ggaaaaaccc ttgggttttt attggagggt tgctgcaagc actcatcacc gctctgggga     1560

cctcttcaag ttctgccacc ctacccatca ccttcaagtg cctggaagag aacaatggcg     1620

tggacaagcg cgtcaccaga ttcgtgctcc ccgtaggagc caccattaac atggatggga     1680

ctgccctcta tgaggctttg gctgccattt tcattgctca agttaacaac tttgaactga     1740

acttcggaca aattattaca atcagcatca cagccacagc tgccagtatt ggggcagctg     1800

gaattcctca ggcgggcctg gtcactatgg tcattgtgct gacatctgtc ggcctgccca     1860

ctgacgacat cacgctcatc atcgcggtgg actggttcct ggatcgcctc cggaccacca     1920

ccaacgtact gggagactcc ctgggagctg ggattgtgga gcacttgtca cgacatgaac     1980

tgaagaacag agatgttgaa atgggtaact cagtgattga agagaatgaa atgaagaaac     2040

catatcaact gattgcacag gacaatgaaa ctgagaaacc catcgacagt gaaaccaaga     2100

tgtagactaa cataaagaaa cactttcttg agcaccaggt gttaaaaacc attataaaat     2160

ctttccatct cattacagct cattcgctcc agcaagcccg tcatcttccc tttcctccct     2220

tctgataaga ctggaaaata gtcctccaaa acacaaggga ggattttggg tggccaaagt     2280

gtacaatttt catcccacaa ttgaaatttt taaatcattt catgttagtc ttaccgaata     2340

aggtaccaag atcacaaata gtgttgatca gatcttacaa gtttatgtgg cacacaatcc     2400

tataaatgtg atttttttat ataagttaaa gagacaaata gtaggctaaa aacattttaa     2460

aatcaacttt tgaaatttaa aaatctttca gaatacaatt cagttttagt ttcaaaatgt     2520

taacaacttg aattacaacc ggttatcagt tggacagtaa gattttatcc ctttctcttc     2580

tgactggtat acctatttca ttagtagcta ggtgcacata tacatctagc acagctgtga     2640

ggacagacag aaggcaaagt ttccatgtgg ccttgagcaa gtcccatctc acctctaggc     2700

ctcagtgtcc tcatctataa aatgagggac ttccctagaa gtcttcatgg tctcttccag     2760

cccagacatc ctgtgatgtc atgaaagcac ctgccctctg tttcccctca gaacaccctg     2820

taccatccat ggagcacgag gccttcagaa aagacacttc aatgggagtg aacatttcta     2880

actaaggaca ggatggctgt gtgtggtggt caccaggtcc tgtgagcaaa gtgcaggtta     2940

tgcaagtcgc caggcaggag gccattccag gagtgggatt attcatcaaa ctctttgccc     3000

agttcatccc aatgggggaa gtattccctt ctttcctact ctgggaagaa tgtctcctgc     3060

cactcctcaa ctgatgatag acttcgaaaa cagatgagaa gactagcagc tagcaagggt     3120

gcttgtggtc acactgtgga acactaaaga gctaggaaag agttgagcac aggcaacatt     3180

acaaacaaag gatttgaaaa caccaagagt acaggtcttc tttaaggaag aataaaaaag     3240

aagaggttca tttttctggc tttttttttc acctgaaaca ctttttctcg agtccaaaat     3300

cattcccccc gtgaagtctg cttaccaaaa cataagacga cttatatatt tgaaagaagt     3360

caaatgaatg agctctctaa tagaagtcca tgagttgagt gggtatttct tatttgaaag     3420

tgtttttctt taatcaaaag tccttagaat gagggaaaca aaatatttat ttgttttgga     3480

atcccactta tcaaatcatt caaaactttc agctggagtg gggtttgctt ttgttttgtt     3540

tgtgtccata agagaaatgg tagaagatga atcagtatga agacactgtc aatgaggtta     3600

tgagaaaaaa acagcagggg cattagtttc aggcaaggca gctcccaggt ttagagatta     3660

atttttaccc cctaaggaat atccagtcaa agacgctgag tgggagctgt caggcagtag     3720

cagctgtgtt tgagtttctg gctgaaaatg gtgaagaatg gacttaatta tgctaacaaa     3780

ctgaaaaatc tagacataga tcctctgata tacaattaga gatattttta tatagacccc     3840

aagcattctg tgcataaaag ttaacattag gctgtggtgc agtaaccatt taatgtcgag     3900

gctctatttc ggaaatacac tacaaatgtt aaagtacgtg gctgtcctct taagacacta     3960

gtagagcaaa gacttaatca tatcaactta attctgttac acaatatgtg ttttttaata     4020

tactaaccat ttcttatgga aaggtcctgt ggggagccca tcctctcgcc aagccatcac     4080

aggctctgca tacacatgca ctcagtgtgg actgggaagc attactttgt agatgtattt     4140

tcaataaaga aaaaaatagt tttacattaa aaaaaaaaaa aaaaaaaa                  4188


<210>  4886
<211>  2417
<212>  DNA
<213>  homo sapiens

<400>  4886
gcagcagaga ggagttgagg gcgatgagag cgggtactgc gaactgccgg gcgatgctgt       60

cgctgccgcc gtgatacgga gagcaacagt tccccagcaa cacccctccc cgacacaggc      120

acacaccccc cgacaggcac gcacacccac cccacagtgc ccggctcggc tgcgcctcct      180

ctattggccc aggaagccca cccagccccg ccacgcagag cccagaagga aagaaagcct      240

catgcctgag ccgaggggag caccatggat ctgacaaaaa tgggcatgat ccagctgcag      300

aaccctagcc accccacggg gctactgtgc aaggccaacc agatgcggct ggccgggact      360

ttgtgcgatg tggtcatcat ggtggacagc caggagttcc acgcccaccg gacggtgctg      420

gcctgcacca gcaagatgtt tgagatcctc ttccaccgca atagtcaaca ctatactttg      480

gacttcctct cgccaaagac cttccagcag attctggagt atgcatatac agccacgctg      540

caagccaagg cggaggacct ggatgacctg ctgtatgcgg ccgagatcct ggagatcgag      600

tacctggagg aacagtgcct gaagatgctg gagaccatcc aggcctcaga cgacaatgac      660

acggaggcca ccatggccga tggcggggcc gaggaagaag aggaccgcaa ggctcggtac      720

ctcaagaaca tcttcatctc gaagcattcc agcgaggaga gtgggtatgc cagtgtggct      780

ggacagagcc tccctgggcc catggtggac cagagccctt cagtctccac ttcatttggt      840

ctttcagcca tgagtcccac caaggctgca gtggacagtt tgatgaccat aggacagtct      900

ctcctgcagg gaactcttca gccacctgca gggcccgagg agccaactct ggctgggggt      960

gggcggcacc ctggggtggc tgaggtgaag acggagatga tgcaggtgga tgaggtgccc     1020

agccaggaca gccctggggc agccgagtcc agcatctcag gagggatggg ggacaaggtt     1080

gaggaaagag gcaaagaggg gcctgggacc ccgactcgaa gcagcgtcat caccagtgct     1140

agggagctac actatgggcg agaggagagt gccgagcagg tgccaccccc agctgaggct     1200

ggccaggccc ccactggccg acctgagcac ccagcacccc cgcctgagaa gcatctgggc     1260

atctactccg tgttgcccaa ccacaaggct gacgctgtat tgagcatgcc gtcttccgtg     1320

acctctggcc tccacgtgca gcctgccctg gctgtctcca tggacttcag cacctatggg     1380

gggctgctgc cccagggctt catccagagg gagctgttca gcaagctggg ggagctggct     1440

gtgggcatga agtcagagag ccggaccatc ggagagcagt gcagcgtgtg tggggtcgag     1500

cttcctgata acgaggctgt ggagcagcac aggaagctgc acagtgggat gaagacgtac     1560

gggtgcgagc tctgcgggaa gcggttcctg gatagtttgc ggctgagaat gcacttactg     1620

gctcattcag cgggtgccaa agcctttgtc tgtgatcagt gcggtgcaca gttttcgaag     1680

gaggatgccc tggagacaca caggcagacc catactggca ctgacatggc cgtcttctgt     1740

ctgctgtgtg ggaagcgctt ccaggcgcag agcgcactgc agcagcacat ggaggtccac     1800

gcgggcgtgc gcagctacat ctgcagtgag tgcaaccgca ccttccccag ccacacggct     1860

ctcaaacgcc acctgcgctc acatacaggc gaccacccct acgagtgtga gttctgtggc     1920

agctgcttcc gggatgagag cacactcaag agccacaaac gcatccacac gggtgagaaa     1980

ccctacgagt gcaatggctg tggcaagaag ttcagcctca agcatcagct ggagacgcac     2040

tatagggtgc acacaggtga gaagcccttt gagtgtaagc tctgccacca gcgctcccgg     2100

gactactcgg ccatgatcaa gcacctgaga acgcacaacg gcgcctcgcc ctaccagtgc     2160

accatctgca cagagtactg ccccagcctc tcctccatgc agaagcacat gaagggccac     2220

aagcccgagg agatcccgcc cgactggagg atagagaaga cgtacctcta cctgtgctat     2280

gtgtgaaggg aggcccgcgg cggtggagcc gagcggggag ccaggaaaga agagttggag     2340

tgagatgaag gaaggactat gacaaataaa aaaggaaaag aaaaaaaaaa acagaaggaa     2400

aaggaaaaaa aaaaaaa                                                    2417


<210>  4887
<211>  2262
<212>  DNA
<213>  homo sapiens

<400>  4887
gcgctcccgg ccgctctcgc ctcctctatt ggcccaggaa gcccacccag ccccgccacg       60

cagagcccag aaggaaagaa agcctcatgc ctgagccgag gggagcacca tggatctgac      120

aaaaatgggc atgatccagc tgcagaaccc tagccacccc acggggctac tgtgcaaggc      180

caaccagatg cggctggccg ggactttgtg cgatgtggtc atcatggtgg acagccagga      240

gttccacgcc caccggacgg tgctggcctg caccagcaag atgtttgaga tcctcttcca      300

ccgcaatagt caacactata ctttggactt cctctcgcca aagaccttcc agcagattct      360

ggagtatgca tatacagcca cgctgcaagc caaggcggag gacctggatg acctgctgta      420

tgcggccgag atcctggaga tcgagtacct ggaggaacag tgcctgaaga tgctggagac      480

catccaggcc tcagacgaca atgacacgga ggccaccatg gccgatggcg gggccgagga      540

agaagaggac cgcaaggctc ggtacctcaa gaacatcttc atctcgaagc attccagcga      600

ggagagtggg tatgccagtg tggctggaca gagcctccct gggcccatgg tggaccagag      660

cccttcagtc tccacttcat ttggtctttc agccatgagt cccaccaagg ctgcagtgga      720

cagtttgatg accataggac agtctctcct gcagggaact cttcagccac ctgcagggcc      780

cgaggagcca actctggctg ggggtgggcg gcaccctggg gtggctgagg tgaagacgga      840

gatgatgcag gtggatgagg tgcccagcca ggacagccct ggggcagccg agtccagcat      900

ctcaggaggg atgggggaca aggttgagga aagaggcaaa gaggggcctg ggaccccgac      960

tcgaagcagc gtcatcacca gtgctaggga gctacactat gggcgagagg agagtgccga     1020

gcaggtgcca cccccagctg aggctggcca ggcccccact ggccgacctg agcacccagc     1080

acccccgcct gagaagcatc tgggcatcta ctccgtgttg cccaaccaca aggctgacgc     1140

tgtattgagc atgccgtctt ccgtgacctc tggcctccac gtgcagcctg ccctggctgt     1200

ctccatggac ttcagcacct atggggggct gctgccccag ggcttcatcc agagggagct     1260

gttcagcaag ctgggggagc tggctgtggg catgaagtca gagagccgga ccatcggaga     1320

gcagtgcagc gtgtgtgggg tcgagcttcc tgataacgag gctgtggagc agcacaggaa     1380

gctgcacagt gggatgaaga cgtacgggtg cgagctctgc gggaagcggt tcctggatag     1440

tttgcggctg agaatgcact tactggctca ttcagcgggt gccaaagcct ttgtctgtga     1500

tcagtgcggt gcacagtttt cgaaggagga tgccctggag acacacaggc agacccatac     1560

tggcactgac atggccgtct tctgtctgct gtgtgggaag cgcttccagg cgcagagcgc     1620

actgcagcag cacatggagg tccacgcggg cgtgcgcagc tacatctgca gtgagtgcaa     1680

ccgcaccttc cccagccaca cggctctcaa acgccacctg cgctcacata caggcgacca     1740

cccctacgag tgtgagttct gtggcagctg cttccgggat gagagcacac tcaagagcca     1800

caaacgcatc cacacgggtg agaaacccta cgagtgcaat ggctgtggca agaagttcag     1860

cctcaagcat cagctggaga cgcactatag ggtgcacaca ggtgagaagc cctttgagtg     1920

taagctctgc caccagcgct cccgggacta ctcggccatg atcaagcacc tgagaacgca     1980

caacggcgcc tcgccctacc agtgcaccat ctgcacagag tactgcccca gcctctcctc     2040

catgcagaag cacatgaagg gccacaagcc cgaggagatc ccgcccgact ggaggataga     2100

gaagacgtac ctctacctgt gctatgtgtg aagggaggcc cgcggcggtg gagccgagcg     2160

gggagccagg aaagaagagt tggagtgaga tgaaggaagg actatgacaa ataaaaaagg     2220

aaaagaaaaa aaaaaacaga aggaaaagga aaaaaaaaaa aa                        2262


<210>  4888
<211>  5591
<212>  DNA
<213>  homo sapiens

<400>  4888
gctactccca ccccgccccg ccccgtcatt gtccccgtcg gtctcttttc tcttccgtcc       60

taaaagctct gcgagccgct cccttctccc ggtgccccgc gtctgtccat cctcagtggg      120

tcagacgagc aggatggagg gctgcatggg ggaggagtcg tttcagatgt gggagctcaa      180

tcggcgcctg gaggcctacc tggcccgggt caaggcgctg gaggagcaga atgagctgct      240

cagcgcggag ctcggggggc tccgggcaca atccgcggac acctcctggc gggcgcatgc      300

cgacgacgag ctggcggccc tgcgggccct cgttgaccaa cgctggcggg agaagcacgc      360

ggccgaggtg gcgcgcgaca acctggctga agagctggag ggcgtggcag gccgatgcca      420

gcagctgcgg ctggcccggg agcggacgac ggaggaggta gcccgcaacc ggcgcgccgt      480

cgaggcagag aaatgcgccc gggcctggct gagtagccag gtggcagagc tggagcgcga      540

gctagaggct ctacgcgtgg cgcacgagga ggagcgcgtc ggcctgaacg cgcaggctgc      600

ctgtgccccc cgctgccccg cgccgccccg cgggcctccc gcgccggccc cggaggtaga      660

ggagctggca aggcgactgg gcgaggcgtg gcgcggggca gtgcgcggct accaggagcg      720

cgtggcacac atggagacgt cgctgggcca ggcccgcgag cggctgggcc gggcggtgca      780

gggtgcccgc gagggccgcc tggagctgca gcagctccag gctgagcgcg gaggcctcct      840

ggagcgcagg gcagcgttgg aacagaggtt ggagggccgc tggcaggagc ggctgcgggc      900

tactgaaaag ttccagctgg ctgtggaggc cctggagcag gagaaacagg gcctacagag      960

ccagatcgct caggtcctgg aaggtcggca gcagctggcg cacctcaaga tgtccctcag     1020

cctggaggtg gccacgtaca ggaccctcct ggaggctgag aactcccggc tgcaaacacc     1080

tggcggtggc tccaagactt ccctcagctt tcaggacccc aagctggagc tgcaattccc     1140

taggacccca gagggccggc gtcttggatc tttgctccca gtcctgagcc caacttccct     1200

cccctcaccc ttgcctgcta cccttgagac acctgtgcca gcctttctta agaaccaaga     1260

attcctccag gcccgtaccc ctaccttggc cagcaccccc atccccccca cacctcaggc     1320

accctctcct gctgtagatg cagagatcag agcccaggat gctcctctct ctctgctcca     1380

gacacagggt gggaggaaac aggctccaga gcccctgcgg gctgaagcca gggtggccat     1440

tcctgccagc gtcctgcctg gaccagagga gcctgggggc cagcggcaag aggccagtac     1500

aggccagtcc ccagaggacc atgcctcctt ggcaccaccc ctcagccctg accactccag     1560

tttagaggct aaggatggag aatccggtgg gtctagagtg ttcagcatat gccgagggga     1620

aggtgaaggg caaatctggg ggttggtaga gaaagaaaca gccatagagg gcaaagtggt     1680

aagcagcttg cagcaggaaa tatgggaaga agaggatcta aacaggaagg aaatccagga     1740

ctcccaggtt cctttggaaa aagaaaccct gaagtctctg ggagaggaga ttcaagagtc     1800

actgaagact ctggaaaacc agagccatga gacactagaa agggagaatc aagaatgtcc     1860

gaggtcttta gaagaagact tagaaacact aaaaagtcta gaaaaggaaa ataaagagct     1920

attaaaggat gtggaggtag tgagacctct agaaaaagag gctgtaggcc aacttaagcc     1980

tacaggaaaa gaggacacac agacattgca atccctgcaa aaggagaatc aagaactaat     2040

gaaatctctt gaaggtaatc tagagacatt tttatttcca ggaacggaaa atcaagaatt     2100

agtaagttct ctgcaagaga acttagagtc attgacagct ctggaaaagg agaatcaaga     2160

gccactgaga tctccagaag taggggatga ggaggcactg agacctctga caaaggagaa     2220

tcaggaaccc ctgaggtctc ttgaagatga gaacaaagag gcctttagat ctctagaaaa     2280

agagaaccag gagccactga agactctaga agaagaggac cagagtattg tgagacctct     2340

agaaacagag aatcacaaat cactgaggtc tttagaagaa caggaccaag agacattgag     2400

aactcttgaa aaagagactc aacagcgacg gaggtctcta ggggaacagg atcagatgac     2460

attaagaccc ccagaaaaag tggatctaga accactgaag tctcttgacc aggagatagc     2520

tagacctctt gaaaatgaga atcaagagtt cttaaagtca ctcaaagaag agagcgtaga     2580

ggcagtaaaa tctttagaaa cagagatcct agaatcactg aagtctgcgg gacaagagaa     2640

cctggaaaca ctgaaatctc cagaaactca agcaccactg tggactccag aagaaataaa     2700

tcagggggca atgaatcctc tagaaaagga aattcaagaa ccactggagt ctgtggaagt     2760

gaaccaagag acattcagac tcctggaaga ggagaatcag gaatcattga gatctctggg     2820

agcatggaac ctggagaatt tgagatctcc agaggaggta gacaaggaaa gtcaaaggaa     2880

tctggaagag gaagagaacc tgggaaaggg agagtaccaa gagtcactga ggtctctgga     2940

ggaggaggga caggagctgc cgcagtctgc agatgtgcag aggtgggaag atacggtgga     3000

gaaggaccaa gaactggctc aggaaagccc tcctgggatg gctggagtgg aaaatgagga     3060

tgaggcagag ctgaatctga gggagcagga tggcttcact gggaaggagg aggtggtaga     3120

gcagggagag ctgaatgcca cagaggaggt ctggatccca ggcgaggggc acccagagag     3180

ccctgagccc aaagagcaga gaggcctggt tgagggagcc agtgtgaagg gaggggctga     3240

gggcctccag gaccctgaag ggcaatcaca acaggtgggg gccccaggcc tccaggctcc     3300

ccaggggctg ccagaggcga tagagcccct ggtggaagat gatgtggccc cagggggtga     3360

ccaagcctcc ccagaggtca tgttggggtc agagcctgcc atgggtgagt ctgctgcggg     3420

agctgagcca ggcccggggc agggggtggg agggctgggg gacccaggcc atctgaccag     3480

ggaagaggtg atggaaccac ccctggaaga ggagagtttg gaggcaaaga gggttcaggg     3540

cttggaaggg cctagaaagg acctagagga ggcaggtggt ctggggacag agttctccga     3600

gctgcctggg aagagcagag acccttggga gcctcccagg gagggtaggg aggagtcaga     3660

ggctgaggcc cccaggggag cagaggaggc gttccctgct gagaccctgg gccacactgg     3720

aagtgatgcc ccttcacctt ggcctctggg gtcagaggaa gctgaggagg atgtaccacc     3780

agtgctggtc tcccccagcc caacgtacac cccgatcctg gaagatgccc ctgggcctca     3840

gcctcaggct gaagggagtc aggaggctag ctggggggtg caggggaggg ctgaagccct     3900

ggggaaagta gagagcgagc aggaggagtt gggttctggg gagatccccg agggccccca     3960

ggaggaaggg gaggagagca gagaagagag cgaggaggat gagctcgggg agacccttcc     4020

agactccact cccctgggct tctacctcag gtcccccacc tcccccaggt gggaccccac     4080

tggagagcag aggccacccc ctcaagggga gactggaaag gagggctggg atcctgctgt     4140

cctggcttcc gagggccttg aggccccacc ctcagaaaag gaggaggggg aggagggaga     4200

agaggagtgt ggccgtgact ctgacctgtc agaagaattt gaggacctgg ggactgaggc     4260

accttttctt cctggggtcc ctggggaggt ggcagaacct ctgggccagg tgccccagct     4320

gctactggat cctgcagcct gggatcgaga tggggagtcc gatgggtttg cagatgagga     4380

agaaagtggg gaggagggag aggaggatca ggaggagggg agggagccag gggctgggcg     4440

gtgggggcca gggtcttctg ttggcagcct ccaggccctg agtagctccc agagagggga     4500

attcctggag tctgattctg tgagtgtcag tgtcccctgg gatgacagct tgaggggtgc     4560

agtggctggt gcccccaaga ctgccctgga aacggagtcc caggacagtg ctgagccttc     4620

tggctcagag gaagagtctg accctgtttc cttggagagg gaggacaaag tccctggccc     4680

tctagagatc cccagtggga tggaggatgc aggcccaggg gcagacatca ttggtgttaa     4740

tggccagggt cccaacttgg aggggaagtc acagcatgtg aatgggggag tgatgaacgg     4800

gctggagcag tctgaggaag tggggcaagg aatgccgcta gtctctgagg gagaccgagg     4860

gagccccttt caggaggagg aggggagtgc tctgaagacc tcttgggcag gggctcctgt     4920

tcacctgggc cagggtcagt tcctgaagtt cactcagagg gaaggagata gagagtcctg     4980

gtcctcaggg gaggactagg aaaagaccat ctgcccggca ctggggactt aggggtgcgg     5040

ggaggggaag gacgcctcca agcccgctcc ctgctcagga gcagcactct taacttacga     5100

tctcttgaca tatggtttct ggctgagagg cctggcccgc taaggtgaaa aggggtgtgg     5160

caaaggagcc tactccaaga atggaggctg taggaatata acctcccacc ctgcaaaggg     5220

aatctcttgc ctgctccatc tcataggcta agtcagctga atcccgatag tactaggtcc     5280

ccttccctcc gcatcccgtc agctggaaaa ggcctgtggc ccagaggctt ctccaaaggg     5340

agggtgacat gctggctttt gtgcccaagc tcaccagccc tgcgccacct cactgcagta     5400

gtgcaccatc tcactgcagt agcacgccct cctgggccgt ctggcctgtg gctaatggag     5460

gtgacggcac tcccatgtgc tgactccccc catccctgcc acgctgtggc cctgcctggc     5520

tagtccctgc ctgaataaag taatgcctcc gcttcaaaaa aaaaaaaaaa aaaaaaaaaa     5580

aaaaaaaaaa a                                                          5591


<210>  4889
<211>  339
<212>  PRT
<213>  homo sapiens

<400>  4889

Met Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu Gly Asp 
1               5                   10                  15      


His Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr Thr Asn 
            20                  25                  30          


Phe Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile Lys Thr 
        35                  40                  45              


Lys Gly Val Asp Glu Val Thr Ile Val Asn Ile Leu Thr Asn Arg Ser 
    50                  55                  60                  


Asn Ala Gln Arg Gln Asp Ile Ala Phe Ala Tyr Gln Arg Arg Thr Lys 
65                  70                  75                  80  


Lys Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His Leu Glu 
                85                  90                  95      


Thr Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp Ala Ser 
            100                 105                 110         


Glu Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp Ser Leu 
        115                 120                 125             


Ile Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu Ile Asn 
    130                 135                 140                 


Arg Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp Ile Ile 
145                 150                 155                 160 


Ser Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu Ala Lys 
                165                 170                 175     


Gly Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu Ile Asp 
            180                 185                 190         


Gln Asp Ala Arg Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys Gly Thr 
        195                 200                 205             


Asp Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val Pro His 
    210                 215                 220                 


Leu Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr Asp Met 
225                 230                 235                 240 


Leu Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn Ala Phe 
                245                 250                 255     


Leu Asn Leu Val Gln Cys Ile Gln Asn Lys Pro Leu Tyr Phe Ala Asp 
            260                 265                 270         


Arg Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys Val Leu 
        275                 280                 285             


Ile Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys Ile Arg 
    290                 295                 300                 


Ser Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr Ile Gln 
305                 310                 315                 320 


Gln Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu Cys Gly 
                325                 330                 335     


Gly Asp Asp 
            


<210>  4890
<211>  339
<212>  PRT
<213>  homo sapiens

<400>  4890

Met Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu Gly Asp 
1               5                   10                  15      


His Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr Thr Asn 
            20                  25                  30          


Phe Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile Lys Thr 
        35                  40                  45              


Lys Gly Val Asp Glu Val Thr Ile Val Asn Ile Leu Thr Asn Arg Ser 
    50                  55                  60                  


Asn Ala Gln Arg Gln Asp Ile Ala Phe Ala Tyr Gln Arg Arg Thr Lys 
65                  70                  75                  80  


Lys Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His Leu Glu 
                85                  90                  95      


Thr Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp Ala Ser 
            100                 105                 110         


Glu Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp Ser Leu 
        115                 120                 125             


Ile Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu Ile Asn 
    130                 135                 140                 


Arg Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp Ile Ile 
145                 150                 155                 160 


Ser Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu Ala Lys 
                165                 170                 175     


Gly Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu Ile Asp 
            180                 185                 190         


Gln Asp Ala Arg Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys Gly Thr 
        195                 200                 205             


Asp Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val Pro His 
    210                 215                 220                 


Leu Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr Asp Met 
225                 230                 235                 240 


Leu Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn Ala Phe 
                245                 250                 255     


Leu Asn Leu Val Gln Cys Ile Gln Asn Lys Pro Leu Tyr Phe Ala Asp 
            260                 265                 270         


Arg Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys Val Leu 
        275                 280                 285             


Ile Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys Ile Arg 
    290                 295                 300                 


Ser Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr Ile Gln 
305                 310                 315                 320 


Gln Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu Cys Gly 
                325                 330                 335     


Gly Asp Asp 
            


<210>  4891
<211>  357
<212>  PRT
<213>  homo sapiens

<400>  4891

Met Gly Arg Gln Leu Ala Gly Cys Gly Asp Ala Gly Lys Lys Ala Ser 
1               5                   10                  15      


Phe Lys Met Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu 
            20                  25                  30          


Gly Asp His Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr 
        35                  40                  45              


Thr Asn Phe Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile 
    50                  55                  60                  


Lys Thr Lys Gly Val Asp Glu Val Thr Ile Val Asn Ile Leu Thr Asn 
65                  70                  75                  80  


Arg Ser Asn Ala Gln Arg Gln Asp Ile Ala Phe Ala Tyr Gln Arg Arg 
                85                  90                  95      


Thr Lys Lys Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His 
            100                 105                 110         


Leu Glu Thr Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp 
        115                 120                 125             


Ala Ser Glu Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp 
    130                 135                 140                 


Ser Leu Ile Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu 
145                 150                 155                 160 


Ile Asn Arg Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp 
                165                 170                 175     


Ile Ile Ser Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu 
            180                 185                 190         


Ala Lys Gly Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu 
        195                 200                 205             


Ile Asp Gln Asp Ala Arg Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys 
    210                 215                 220                 


Gly Thr Asp Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val 
225                 230                 235                 240 


Pro His Leu Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr 
                245                 250                 255     


Asp Met Leu Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn 
            260                 265                 270         


Ala Phe Leu Asn Leu Val Gln Cys Ile Gln Asn Lys Pro Leu Tyr Phe 
        275                 280                 285             


Ala Asp Arg Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys 
    290                 295                 300                 


Val Leu Ile Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys 
305                 310                 315                 320 


Ile Arg Ser Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr 
                325                 330                 335     


Ile Gln Gln Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu 
            340                 345                 350         


Cys Gly Gly Asp Asp 
        355         


<210>  4892
<211>  339
<212>  PRT
<213>  homo sapiens

<400>  4892

Met Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu Gly Asp 
1               5                   10                  15      


His Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr Thr Asn 
            20                  25                  30          


Phe Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile Lys Thr 
        35                  40                  45              


Lys Gly Val Asp Glu Val Thr Ile Val Asn Ile Leu Thr Asn Arg Ser 
    50                  55                  60                  


Asn Ala Gln Arg Gln Asp Ile Ala Phe Ala Tyr Gln Arg Arg Thr Lys 
65                  70                  75                  80  


Lys Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His Leu Glu 
                85                  90                  95      


Thr Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp Ala Ser 
            100                 105                 110         


Glu Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp Ser Leu 
        115                 120                 125             


Ile Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu Ile Asn 
    130                 135                 140                 


Arg Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp Ile Ile 
145                 150                 155                 160 


Ser Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu Ala Lys 
                165                 170                 175     


Gly Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu Ile Asp 
            180                 185                 190         


Gln Asp Ala Arg Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys Gly Thr 
        195                 200                 205             


Asp Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val Pro His 
    210                 215                 220                 


Leu Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr Asp Met 
225                 230                 235                 240 


Leu Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn Ala Phe 
                245                 250                 255     


Leu Asn Leu Val Gln Cys Ile Gln Asn Lys Pro Leu Tyr Phe Ala Asp 
            260                 265                 270         


Arg Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys Val Leu 
        275                 280                 285             


Ile Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys Ile Arg 
    290                 295                 300                 


Ser Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr Ile Gln 
305                 310                 315                 320 


Gln Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu Cys Gly 
                325                 330                 335     


Gly Asp Asp 
            


<210>  4893
<211>  1486
<212>  PRT
<213>  homo sapiens

<400>  4893

Met Ala Ala Asn Val Gly Ser Met Phe Gln Tyr Trp Lys Arg Phe Asp 
1               5                   10                  15      


Leu Arg Arg Leu Gln Lys Glu Leu Asn Ser Val Ala Ser Glu Leu Ser 
            20                  25                  30          


Ala Arg Gln Glu Glu Ser Glu His Ser His Lys His Leu Ile Glu Leu 
        35                  40                  45              


Arg Arg Glu Phe Lys Lys Asn Val Pro Glu Glu Ile Arg Glu Met Val 
    50                  55                  60                  


Ala Pro Val Leu Lys Ser Phe Gln Ala Glu Val Val Ala Leu Ser Lys 
65                  70                  75                  80  


Arg Ser Gln Glu Ala Glu Ala Ala Phe Leu Ser Val Tyr Lys Gln Leu 
                85                  90                  95      


Ile Glu Ala Pro Asp Pro Val Pro Val Phe Glu Ala Ala Arg Ser Leu 
            100                 105                 110         


Asp Asp Arg Leu Gln Pro Pro Ser Phe Asp Pro Ser Gly Gln Pro Arg 
        115                 120                 125             


Arg Asp Leu His Thr Ser Trp Lys Arg Asn Pro Glu Leu Leu Ser Pro 
    130                 135                 140                 


Lys Glu Gln Arg Glu Gly Thr Ser Pro Ala Gly Pro Thr Leu Thr Glu 
145                 150                 155                 160 


Gly Ser Arg Leu Pro Gly Ile Pro Gly Lys Ala Leu Leu Thr Glu Thr 
                165                 170                 175     


Leu Leu Gln Arg Asn Glu Ala Glu Lys Gln Lys Gly Leu Gln Glu Val 
            180                 185                 190         


Gln Ile Thr Leu Ala Ala Arg Leu Gly Glu Ala Glu Glu Lys Ile Lys 
        195                 200                 205             


Val Leu His Ser Ala Leu Lys Ala Thr Gln Ala Glu Leu Leu Glu Leu 
    210                 215                 220                 


Arg Arg Lys Tyr Asp Glu Glu Ala Ala Ser Lys Ala Asp Glu Val Gly 
225                 230                 235                 240 


Leu Ile Met Thr Asn Leu Glu Lys Ala Asn Gln Arg Ala Glu Ala Ala 
                245                 250                 255     


Gln Arg Glu Val Glu Ser Leu Arg Glu Gln Leu Ala Ser Val Asn Ser 
            260                 265                 270         


Ser Ile Arg Leu Ala Cys Cys Ser Pro Gln Gly Pro Ser Gly Asp Lys 
        275                 280                 285             


Val Asn Phe Thr Leu Cys Ser Gly Pro Arg Leu Glu Ala Ala Leu Ala 
    290                 295                 300                 


Ser Lys Asp Arg Glu Ile Leu Arg Leu Leu Lys Asp Val Gln His Leu 
305                 310                 315                 320 


Gln Ser Ser Leu Gln Glu Leu Glu Glu Ala Ser Ala Asn Gln Ile Ala 
                325                 330                 335     


Asp Leu Glu Arg Gln Leu Thr Ala Lys Ser Glu Ala Ile Glu Lys Leu 
            340                 345                 350         


Glu Glu Lys Leu Gln Ala Gln Ser Asp Tyr Glu Glu Ile Lys Thr Glu 
        355                 360                 365             


Leu Ser Ile Leu Lys Ala Met Lys Leu Ala Ser Ser Thr Cys Ser Leu 
    370                 375                 380                 


Pro Gln Gly Met Ala Lys Pro Glu Asp Ser Leu Leu Ile Ala Lys Glu 
385                 390                 395                 400 


Ala Phe Phe Pro Thr Gln Lys Phe Leu Leu Glu Lys Pro Ser Leu Leu 
                405                 410                 415     


Ala Ser Pro Glu Glu Asp Pro Ser Glu Asp Asp Ser Ile Lys Asp Ser 
            420                 425                 430         


Leu Gly Thr Glu Gln Ser Tyr Pro Ser Pro Gln Gln Leu Pro Pro Pro 
        435                 440                 445             


Pro Gly Pro Glu Asp Pro Leu Ser Pro Ser Pro Gly Gln Pro Leu Leu 
    450                 455                 460                 


Gly Pro Ser Leu Gly Pro Asp Gly Thr Arg Thr Phe Ser Leu Ser Pro 
465                 470                 475                 480 


Phe Pro Ser Leu Ala Ser Gly Glu Arg Leu Met Met Pro Pro Ala Ala 
                485                 490                 495     


Phe Lys Gly Glu Ala Gly Gly Leu Leu Val Phe Pro Pro Ala Phe Tyr 
            500                 505                 510         


Gly Ala Lys Pro Pro Thr Ala Pro Ala Thr Pro Ala Pro Gly Pro Glu 
        515                 520                 525             


Pro Leu Gly Gly Pro Glu Pro Ala Asp Gly Gly Gly Gly Gly Ala Ala 
    530                 535                 540                 


Gly Pro Gly Ala Glu Glu Glu Gln Leu Asp Thr Ala Glu Ile Ala Phe 
545                 550                 555                 560 


Gln Val Lys Glu Gln Leu Leu Lys His Asn Ile Gly Gln Arg Val Phe 
                565                 570                 575     


Gly His Tyr Val Leu Gly Leu Ser Gln Gly Ser Val Ser Glu Ile Leu 
            580                 585                 590         


Ala Arg Pro Lys Pro Trp Arg Lys Leu Thr Val Lys Gly Lys Glu Pro 
        595                 600                 605             


Phe Ile Lys Met Lys Gln Phe Leu Ser Asp Glu Gln Asn Val Leu Ala 
    610                 615                 620                 


Leu Arg Thr Ile Gln Val Arg Gln Arg Gly Ser Ile Thr Pro Arg Ile 
625                 630                 635                 640 


Arg Thr Pro Glu Thr Gly Ser Asp Asp Ala Ile Lys Ser Ile Leu Glu 
                645                 650                 655     


Gln Ala Lys Lys Glu Ile Glu Ser Gln Lys Gly Gly Glu Pro Lys Thr 
            660                 665                 670         


Ser Val Ala Pro Leu Ser Ile Ala Asn Gly Thr Thr Pro Ala Ser Thr 
        675                 680                 685             


Ser Glu Asp Ala Ile Lys Ser Ile Leu Glu Gln Ala Arg Arg Glu Met 
    690                 695                 700                 


Gln Ala Gln Gln Gln Ala Leu Leu Glu Met Glu Val Ala Pro Arg Gly 
705                 710                 715                 720 


Arg Ser Val Pro Pro Ser Pro Pro Glu Arg Pro Ser Leu Ala Thr Ala 
                725                 730                 735     


Ser Gln Asn Gly Ala Pro Ala Leu Val Lys Gln Glu Glu Gly Ser Gly 
            740                 745                 750         


Gly Pro Ala Gln Ala Pro Leu Pro Val Leu Ser Pro Ala Ala Phe Val 
        755                 760                 765             


Gln Ser Ile Ile Arg Lys Val Lys Ser Glu Ile Gly Asp Ala Gly Tyr 
    770                 775                 780                 


Phe Asp His His Trp Ala Ser Asp Arg Gly Leu Leu Ser Arg Pro Tyr 
785                 790                 795                 800 


Ala Ser Val Ser Pro Ser Leu Ser Ser Ser Ser Ser Ser Gly Tyr Ser 
                805                 810                 815     


Gly Gln Pro Asn Gly Arg Ala Trp Pro Arg Gly Asp Glu Ala Pro Val 
            820                 825                 830         


Pro Pro Glu Asp Glu Ala Ala Ala Gly Ala Glu Asp Glu Pro Pro Arg 
        835                 840                 845             


Thr Gly Glu Leu Lys Ala Glu Gly Ala Thr Ala Glu Ala Gly Ala Arg 
    850                 855                 860                 


Leu Pro Tyr Tyr Pro Ala Tyr Val Pro Arg Thr Leu Lys Pro Thr Val 
865                 870                 875                 880 


Pro Pro Leu Thr Pro Glu Gln Tyr Glu Leu Tyr Met Tyr Arg Glu Val 
                885                 890                 895     


Asp Thr Leu Glu Leu Thr Arg Gln Val Lys Glu Lys Leu Ala Lys Asn 
            900                 905                 910         


Gly Ile Cys Gln Arg Ile Phe Gly Glu Lys Val Leu Gly Leu Ser Gln 
        915                 920                 925             


Gly Ser Val Ser Asp Met Leu Ser Arg Pro Lys Pro Trp Ser Lys Leu 
    930                 935                 940                 


Thr Gln Lys Gly Arg Glu Pro Phe Ile Arg Met Gln Leu Trp Leu Ser 
945                 950                 955                 960 


Asp Gln Leu Gly Gln Ala Val Gly Gln Gln Pro Gly Ala Ser Gln Ala 
                965                 970                 975     


Ser Pro Thr Glu Pro Arg Ser Ser Pro Ser Pro Pro Pro Ser Pro Thr 
            980                 985                 990         


Glu Pro Glu Lys Ser Ser Gln Glu  Pro Leu Ser Leu Ser  Leu Glu Ser 
        995                 1000                 1005             


Ser Lys  Glu Asn Gln Gln Pro  Glu Gly Arg Ser Ser  Ser Ser Leu 
    1010                 1015                 1020             


Ser Gly  Lys Met Tyr Ser Gly  Ser Gln Ala Pro Gly  Gly Ile Gln 
    1025                 1030                 1035             


Glu Ile  Val Ala Met Ser Pro  Glu Leu Asp Thr Tyr  Ser Ile Thr 
    1040                 1045                 1050             


Lys Arg  Val Lys Glu Val Leu  Thr Asp Asn Asn Leu  Gly Gln Arg 
    1055                 1060                 1065             


Leu Phe  Gly Glu Ser Ile Leu  Gly Leu Thr Gln Gly  Ser Val Ser 
    1070                 1075                 1080             


Asp Leu  Leu Ser Arg Pro Lys  Pro Trp His Lys Leu  Ser Leu Lys 
    1085                 1090                 1095             


Gly Arg  Glu Pro Phe Val Arg  Met Gln Leu Trp Leu  Asn Asp Pro 
    1100                 1105                 1110             


His Asn  Val Glu Lys Leu Arg  Asp Met Lys Lys Leu  Glu Lys Lys 
    1115                 1120                 1125             


Ala Tyr  Leu Lys Arg Arg Tyr  Gly Leu Ile Ser Thr  Gly Ser Asp 
    1130                 1135                 1140             


Ser Glu  Ser Pro Ala Thr Arg  Ser Glu Cys Pro Ser  Pro Cys Leu 
    1145                 1150                 1155             


Gln Pro  Gln Asp Leu Ser Leu  Leu Gln Ile Lys Lys  Pro Arg Val 
    1160                 1165                 1170             


Val Leu  Ala Pro Glu Glu Lys  Glu Ala Leu Arg Lys  Ala Tyr Gln 
    1175                 1180                 1185             


Leu Glu  Pro Tyr Pro Ser Gln  Gln Thr Ile Glu Leu  Leu Ser Phe 
    1190                 1195                 1200             


Gln Leu  Asn Leu Lys Thr Asn  Thr Val Ile Asn Trp  Phe His Asn 
    1205                 1210                 1215             


Tyr Arg  Ser Arg Met Arg Arg  Glu Met Leu Val Glu  Gly Thr Gln 
    1220                 1225                 1230             


Asp Glu  Pro Asp Leu Asp Pro  Ser Gly Gly Pro Gly  Ile Leu Pro 
    1235                 1240                 1245             


Pro Gly  His Ser His Pro Asp  Pro Thr Pro Gln Ser  Pro Asp Ser 
    1250                 1255                 1260             


Glu Thr  Glu Asp Gln Lys Pro  Thr Val Lys Glu Leu  Glu Leu Gln 
    1265                 1270                 1275             


Glu Gly  Pro Glu Glu Asn Ser  Thr Pro Leu Thr Thr  Gln Asp Lys 
    1280                 1285                 1290             


Ala Gln  Val Arg Ile Lys Gln  Glu Gln Met Glu Glu  Asp Ala Glu 
    1295                 1300                 1305             


Glu Glu  Ala Gly Ser Gln Pro  Gln Asp Ser Gly Glu  Leu Asp Lys 
    1310                 1315                 1320             


Gly Gln  Gly Pro Pro Lys Glu  Glu His Pro Asp Pro  Pro Gly Asn 
    1325                 1330                 1335             


Asp Gly  Leu Pro Lys Val Ala  Pro Gly Pro Leu Leu  Pro Gly Gly 
    1340                 1345                 1350             


Ser Thr  Pro Asp Cys Pro Ser  Leu His Pro Gln Gln  Glu Ser Glu 
    1355                 1360                 1365             


Ala Gly  Glu Arg Leu His Pro  Asp Pro Leu Ser Phe  Lys Ser Ala 
    1370                 1375                 1380             


Ser Glu  Ser Ser Arg Cys Ser  Leu Glu Val Ser Leu  Asn Ser Pro 
    1385                 1390                 1395             


Ser Ala  Ala Ser Ser Pro Gly  Leu Met Met Ser Val  Ser Pro Val 
    1400                 1405                 1410             


Pro Ser  Ser Ser Ala Pro Ile  Ser Pro Ser Pro Pro  Gly Ala Pro 
    1415                 1420                 1425             


Pro Ala  Lys Val Pro Ser Ala  Ser Pro Thr Ala Asp  Met Ala Gly 
    1430                 1435                 1440             


Ala Leu  His Pro Ser Ala Lys  Val Asn Pro Asn Leu  Gln Arg Arg 
    1445                 1450                 1455             


His Glu  Lys Met Ala Asn Leu  Asn Asn Ile Ile Tyr  Arg Val Glu 
    1460                 1465                 1470             


Arg Ala  Ala Asn Arg Glu Glu  Ala Leu Glu Trp Glu  Phe 
    1475                 1480                 1485     


<210>  4894
<211>  1210
<212>  PRT
<213>  homo sapiens

<400>  4894

Met Arg Pro Ser Gly Thr Ala Gly Ala Ala Leu Leu Ala Leu Leu Ala 
1               5                   10                  15      


Ala Leu Cys Pro Ala Ser Arg Ala Leu Glu Glu Lys Lys Val Cys Gln 
            20                  25                  30          


Gly Thr Ser Asn Lys Leu Thr Gln Leu Gly Thr Phe Glu Asp His Phe 
        35                  40                  45              


Leu Ser Leu Gln Arg Met Phe Asn Asn Cys Glu Val Val Leu Gly Asn 
    50                  55                  60                  


Leu Glu Ile Thr Tyr Val Gln Arg Asn Tyr Asp Leu Ser Phe Leu Lys 
65                  70                  75                  80  


Thr Ile Gln Glu Val Ala Gly Tyr Val Leu Ile Ala Leu Asn Thr Val 
                85                  90                  95      


Glu Arg Ile Pro Leu Glu Asn Leu Gln Ile Ile Arg Gly Asn Met Tyr 
            100                 105                 110         


Tyr Glu Asn Ser Tyr Ala Leu Ala Val Leu Ser Asn Tyr Asp Ala Asn 
        115                 120                 125             


Lys Thr Gly Leu Lys Glu Leu Pro Met Arg Asn Leu Gln Glu Ile Leu 
    130                 135                 140                 


His Gly Ala Val Arg Phe Ser Asn Asn Pro Ala Leu Cys Asn Val Glu 
145                 150                 155                 160 


Ser Ile Gln Trp Arg Asp Ile Val Ser Ser Asp Phe Leu Ser Asn Met 
                165                 170                 175     


Ser Met Asp Phe Gln Asn His Leu Gly Ser Cys Gln Lys Cys Asp Pro 
            180                 185                 190         


Ser Cys Pro Asn Gly Ser Cys Trp Gly Ala Gly Glu Glu Asn Cys Gln 
        195                 200                 205             


Lys Leu Thr Lys Ile Ile Cys Ala Gln Gln Cys Ser Gly Arg Cys Arg 
    210                 215                 220                 


Gly Lys Ser Pro Ser Asp Cys Cys His Asn Gln Cys Ala Ala Gly Cys 
225                 230                 235                 240 


Thr Gly Pro Arg Glu Ser Asp Cys Leu Val Cys Arg Lys Phe Arg Asp 
                245                 250                 255     


Glu Ala Thr Cys Lys Asp Thr Cys Pro Pro Leu Met Leu Tyr Asn Pro 
            260                 265                 270         


Thr Thr Tyr Gln Met Asp Val Asn Pro Glu Gly Lys Tyr Ser Phe Gly 
        275                 280                 285             


Ala Thr Cys Val Lys Lys Cys Pro Arg Asn Tyr Val Val Thr Asp His 
    290                 295                 300                 


Gly Ser Cys Val Arg Ala Cys Gly Ala Asp Ser Tyr Glu Met Glu Glu 
305                 310                 315                 320 


Asp Gly Val Arg Lys Cys Lys Lys Cys Glu Gly Pro Cys Arg Lys Val 
                325                 330                 335     


Cys Asn Gly Ile Gly Ile Gly Glu Phe Lys Asp Ser Leu Ser Ile Asn 
            340                 345                 350         


Ala Thr Asn Ile Lys His Phe Lys Asn Cys Thr Ser Ile Ser Gly Asp 
        355                 360                 365             


Leu His Ile Leu Pro Val Ala Phe Arg Gly Asp Ser Phe Thr His Thr 
    370                 375                 380                 


Pro Pro Leu Asp Pro Gln Glu Leu Asp Ile Leu Lys Thr Val Lys Glu 
385                 390                 395                 400 


Ile Thr Gly Phe Leu Leu Ile Gln Ala Trp Pro Glu Asn Arg Thr Asp 
                405                 410                 415     


Leu His Ala Phe Glu Asn Leu Glu Ile Ile Arg Gly Arg Thr Lys Gln 
            420                 425                 430         


His Gly Gln Phe Ser Leu Ala Val Val Ser Leu Asn Ile Thr Ser Leu 
        435                 440                 445             


Gly Leu Arg Ser Leu Lys Glu Ile Ser Asp Gly Asp Val Ile Ile Ser 
    450                 455                 460                 


Gly Asn Lys Asn Leu Cys Tyr Ala Asn Thr Ile Asn Trp Lys Lys Leu 
465                 470                 475                 480 


Phe Gly Thr Ser Gly Gln Lys Thr Lys Ile Ile Ser Asn Arg Gly Glu 
                485                 490                 495     


Asn Ser Cys Lys Ala Thr Gly Gln Val Cys His Ala Leu Cys Ser Pro 
            500                 505                 510         


Glu Gly Cys Trp Gly Pro Glu Pro Arg Asp Cys Val Ser Cys Arg Asn 
        515                 520                 525             


Val Ser Arg Gly Arg Glu Cys Val Asp Lys Cys Asn Leu Leu Glu Gly 
    530                 535                 540                 


Glu Pro Arg Glu Phe Val Glu Asn Ser Glu Cys Ile Gln Cys His Pro 
545                 550                 555                 560 


Glu Cys Leu Pro Gln Ala Met Asn Ile Thr Cys Thr Gly Arg Gly Pro 
                565                 570                 575     


Asp Asn Cys Ile Gln Cys Ala His Tyr Ile Asp Gly Pro His Cys Val 
            580                 585                 590         


Lys Thr Cys Pro Ala Gly Val Met Gly Glu Asn Asn Thr Leu Val Trp 
        595                 600                 605             


Lys Tyr Ala Asp Ala Gly His Val Cys His Leu Cys His Pro Asn Cys 
    610                 615                 620                 


Thr Tyr Gly Cys Thr Gly Pro Gly Leu Glu Gly Cys Pro Thr Asn Gly 
625                 630                 635                 640 


Pro Lys Ile Pro Ser Ile Ala Thr Gly Met Val Gly Ala Leu Leu Leu 
                645                 650                 655     


Leu Leu Val Val Ala Leu Gly Ile Gly Leu Phe Met Arg Arg Arg His 
            660                 665                 670         


Ile Val Arg Lys Arg Thr Leu Arg Arg Leu Leu Gln Glu Arg Glu Leu 
        675                 680                 685             


Val Glu Pro Leu Thr Pro Ser Gly Glu Ala Pro Asn Gln Ala Leu Leu 
    690                 695                 700                 


Arg Ile Leu Lys Glu Thr Glu Phe Lys Lys Ile Lys Val Leu Gly Ser 
705                 710                 715                 720 


Gly Ala Phe Gly Thr Val Tyr Lys Gly Leu Trp Ile Pro Glu Gly Glu 
                725                 730                 735     


Lys Val Lys Ile Pro Val Ala Ile Lys Glu Leu Arg Glu Ala Thr Ser 
            740                 745                 750         


Pro Lys Ala Asn Lys Glu Ile Leu Asp Glu Ala Tyr Val Met Ala Ser 
        755                 760                 765             


Val Asp Asn Pro His Val Cys Arg Leu Leu Gly Ile Cys Leu Thr Ser 
    770                 775                 780                 


Thr Val Gln Leu Ile Thr Gln Leu Met Pro Phe Gly Cys Leu Leu Asp 
785                 790                 795                 800 


Tyr Val Arg Glu His Lys Asp Asn Ile Gly Ser Gln Tyr Leu Leu Asn 
                805                 810                 815     


Trp Cys Val Gln Ile Ala Lys Gly Met Asn Tyr Leu Glu Asp Arg Arg 
            820                 825                 830         


Leu Val His Arg Asp Leu Ala Ala Arg Asn Val Leu Val Lys Thr Pro 
        835                 840                 845             


Gln His Val Lys Ile Thr Asp Phe Gly Leu Ala Lys Leu Leu Gly Ala 
    850                 855                 860                 


Glu Glu Lys Glu Tyr His Ala Glu Gly Gly Lys Val Pro Ile Lys Trp 
865                 870                 875                 880 


Met Ala Leu Glu Ser Ile Leu His Arg Ile Tyr Thr His Gln Ser Asp 
                885                 890                 895     


Val Trp Ser Tyr Gly Val Thr Val Trp Glu Leu Met Thr Phe Gly Ser 
            900                 905                 910         


Lys Pro Tyr Asp Gly Ile Pro Ala Ser Glu Ile Ser Ser Ile Leu Glu 
        915                 920                 925             


Lys Gly Glu Arg Leu Pro Gln Pro Pro Ile Cys Thr Ile Asp Val Tyr 
    930                 935                 940                 


Met Ile Met Val Lys Cys Trp Met Ile Asp Ala Asp Ser Arg Pro Lys 
945                 950                 955                 960 


Phe Arg Glu Leu Ile Ile Glu Phe Ser Lys Met Ala Arg Asp Pro Gln 
                965                 970                 975     


Arg Tyr Leu Val Ile Gln Gly Asp Glu Arg Met His Leu Pro Ser Pro 
            980                 985                 990         


Thr Asp Ser Asn Phe Tyr Arg Ala  Leu Met Asp Glu Glu  Asp Met Asp 
        995                 1000                 1005             


Asp Val  Val Asp Ala Asp Glu  Tyr Leu Ile Pro Gln  Gln Gly Phe 
    1010                 1015                 1020             


Phe Ser  Ser Pro Ser Thr Ser  Arg Thr Pro Leu Leu  Ser Ser Leu 
    1025                 1030                 1035             


Ser Ala  Thr Ser Asn Asn Ser  Thr Val Ala Cys Ile  Asp Arg Asn 
    1040                 1045                 1050             


Gly Leu  Gln Ser Cys Pro Ile  Lys Glu Asp Ser Phe  Leu Gln Arg 
    1055                 1060                 1065             


Tyr Ser  Ser Asp Pro Thr Gly  Ala Leu Thr Glu Asp  Ser Ile Asp 
    1070                 1075                 1080             


Asp Thr  Phe Leu Pro Val Pro  Glu Tyr Ile Asn Gln  Ser Val Pro 
    1085                 1090                 1095             


Lys Arg  Pro Ala Gly Ser Val  Gln Asn Pro Val Tyr  His Asn Gln 
    1100                 1105                 1110             


Pro Leu  Asn Pro Ala Pro Ser  Arg Asp Pro His Tyr  Gln Asp Pro 
    1115                 1120                 1125             


His Ser  Thr Ala Val Gly Asn  Pro Glu Tyr Leu Asn  Thr Val Gln 
    1130                 1135                 1140             


Pro Thr  Cys Val Asn Ser Thr  Phe Asp Ser Pro Ala  His Trp Ala 
    1145                 1150                 1155             


Gln Lys  Gly Ser His Gln Ile  Ser Leu Asp Asn Pro  Asp Tyr Gln 
    1160                 1165                 1170             


Gln Asp  Phe Phe Pro Lys Glu  Ala Lys Pro Asn Gly  Ile Phe Lys 
    1175                 1180                 1185             


Gly Ser  Thr Ala Glu Asn Ala  Glu Tyr Leu Arg Val  Ala Pro Gln 
    1190                 1195                 1200             


Ser Ser  Glu Phe Ile Gly Ala  
    1205                 1210 


<210>  4895
<211>  628
<212>  PRT
<213>  homo sapiens

<400>  4895

Met Arg Pro Ser Gly Thr Ala Gly Ala Ala Leu Leu Ala Leu Leu Ala 
1               5                   10                  15      


Ala Leu Cys Pro Ala Ser Arg Ala Leu Glu Glu Lys Lys Val Cys Gln 
            20                  25                  30          


Gly Thr Ser Asn Lys Leu Thr Gln Leu Gly Thr Phe Glu Asp His Phe 
        35                  40                  45              


Leu Ser Leu Gln Arg Met Phe Asn Asn Cys Glu Val Val Leu Gly Asn 
    50                  55                  60                  


Leu Glu Ile Thr Tyr Val Gln Arg Asn Tyr Asp Leu Ser Phe Leu Lys 
65                  70                  75                  80  


Thr Ile Gln Glu Val Ala Gly Tyr Val Leu Ile Ala Leu Asn Thr Val 
                85                  90                  95      


Glu Arg Ile Pro Leu Glu Asn Leu Gln Ile Ile Arg Gly Asn Met Tyr 
            100                 105                 110         


Tyr Glu Asn Ser Tyr Ala Leu Ala Val Leu Ser Asn Tyr Asp Ala Asn 
        115                 120                 125             


Lys Thr Gly Leu Lys Glu Leu Pro Met Arg Asn Leu Gln Glu Ile Leu 
    130                 135                 140                 


His Gly Ala Val Arg Phe Ser Asn Asn Pro Ala Leu Cys Asn Val Glu 
145                 150                 155                 160 


Ser Ile Gln Trp Arg Asp Ile Val Ser Ser Asp Phe Leu Ser Asn Met 
                165                 170                 175     


Ser Met Asp Phe Gln Asn His Leu Gly Ser Cys Gln Lys Cys Asp Pro 
            180                 185                 190         


Ser Cys Pro Asn Gly Ser Cys Trp Gly Ala Gly Glu Glu Asn Cys Gln 
        195                 200                 205             


Lys Leu Thr Lys Ile Ile Cys Ala Gln Gln Cys Ser Gly Arg Cys Arg 
    210                 215                 220                 


Gly Lys Ser Pro Ser Asp Cys Cys His Asn Gln Cys Ala Ala Gly Cys 
225                 230                 235                 240 


Thr Gly Pro Arg Glu Ser Asp Cys Leu Val Cys Arg Lys Phe Arg Asp 
                245                 250                 255     


Glu Ala Thr Cys Lys Asp Thr Cys Pro Pro Leu Met Leu Tyr Asn Pro 
            260                 265                 270         


Thr Thr Tyr Gln Met Asp Val Asn Pro Glu Gly Lys Tyr Ser Phe Gly 
        275                 280                 285             


Ala Thr Cys Val Lys Lys Cys Pro Arg Asn Tyr Val Val Thr Asp His 
    290                 295                 300                 


Gly Ser Cys Val Arg Ala Cys Gly Ala Asp Ser Tyr Glu Met Glu Glu 
305                 310                 315                 320 


Asp Gly Val Arg Lys Cys Lys Lys Cys Glu Gly Pro Cys Arg Lys Val 
                325                 330                 335     


Cys Asn Gly Ile Gly Ile Gly Glu Phe Lys Asp Ser Leu Ser Ile Asn 
            340                 345                 350         


Ala Thr Asn Ile Lys His Phe Lys Asn Cys Thr Ser Ile Ser Gly Asp 
        355                 360                 365             


Leu His Ile Leu Pro Val Ala Phe Arg Gly Asp Ser Phe Thr His Thr 
    370                 375                 380                 


Pro Pro Leu Asp Pro Gln Glu Leu Asp Ile Leu Lys Thr Val Lys Glu 
385                 390                 395                 400 


Ile Thr Gly Phe Leu Leu Ile Gln Ala Trp Pro Glu Asn Arg Thr Asp 
                405                 410                 415     


Leu His Ala Phe Glu Asn Leu Glu Ile Ile Arg Gly Arg Thr Lys Gln 
            420                 425                 430         


His Gly Gln Phe Ser Leu Ala Val Val Ser Leu Asn Ile Thr Ser Leu 
        435                 440                 445             


Gly Leu Arg Ser Leu Lys Glu Ile Ser Asp Gly Asp Val Ile Ile Ser 
    450                 455                 460                 


Gly Asn Lys Asn Leu Cys Tyr Ala Asn Thr Ile Asn Trp Lys Lys Leu 
465                 470                 475                 480 


Phe Gly Thr Ser Gly Gln Lys Thr Lys Ile Ile Ser Asn Arg Gly Glu 
                485                 490                 495     


Asn Ser Cys Lys Ala Thr Gly Gln Val Cys His Ala Leu Cys Ser Pro 
            500                 505                 510         


Glu Gly Cys Trp Gly Pro Glu Pro Arg Asp Cys Val Ser Cys Arg Asn 
        515                 520                 525             


Val Ser Arg Gly Arg Glu Cys Val Asp Lys Cys Asn Leu Leu Glu Gly 
    530                 535                 540                 


Glu Pro Arg Glu Phe Val Glu Asn Ser Glu Cys Ile Gln Cys His Pro 
545                 550                 555                 560 


Glu Cys Leu Pro Gln Ala Met Asn Ile Thr Cys Thr Gly Arg Gly Pro 
                565                 570                 575     


Asp Asn Cys Ile Gln Cys Ala His Tyr Ile Asp Gly Pro His Cys Val 
            580                 585                 590         


Lys Thr Cys Pro Ala Gly Val Met Gly Glu Asn Asn Thr Leu Val Trp 
        595                 600                 605             


Lys Tyr Ala Asp Ala Gly His Val Cys His Leu Cys His Pro Asn Cys 
    610                 615                 620                 


Thr Tyr Gly Ser 
625             


<210>  4896
<211>  405
<212>  PRT
<213>  homo sapiens

<400>  4896

Met Arg Pro Ser Gly Thr Ala Gly Ala Ala Leu Leu Ala Leu Leu Ala 
1               5                   10                  15      


Ala Leu Cys Pro Ala Ser Arg Ala Leu Glu Glu Lys Lys Val Cys Gln 
            20                  25                  30          


Gly Thr Ser Asn Lys Leu Thr Gln Leu Gly Thr Phe Glu Asp His Phe 
        35                  40                  45              


Leu Ser Leu Gln Arg Met Phe Asn Asn Cys Glu Val Val Leu Gly Asn 
    50                  55                  60                  


Leu Glu Ile Thr Tyr Val Gln Arg Asn Tyr Asp Leu Ser Phe Leu Lys 
65                  70                  75                  80  


Thr Ile Gln Glu Val Ala Gly Tyr Val Leu Ile Ala Leu Asn Thr Val 
                85                  90                  95      


Glu Arg Ile Pro Leu Glu Asn Leu Gln Ile Ile Arg Gly Asn Met Tyr 
            100                 105                 110         


Tyr Glu Asn Ser Tyr Ala Leu Ala Val Leu Ser Asn Tyr Asp Ala Asn 
        115                 120                 125             


Lys Thr Gly Leu Lys Glu Leu Pro Met Arg Asn Leu Gln Glu Ile Leu 
    130                 135                 140                 


His Gly Ala Val Arg Phe Ser Asn Asn Pro Ala Leu Cys Asn Val Glu 
145                 150                 155                 160 


Ser Ile Gln Trp Arg Asp Ile Val Ser Ser Asp Phe Leu Ser Asn Met 
                165                 170                 175     


Ser Met Asp Phe Gln Asn His Leu Gly Ser Cys Gln Lys Cys Asp Pro 
            180                 185                 190         


Ser Cys Pro Asn Gly Ser Cys Trp Gly Ala Gly Glu Glu Asn Cys Gln 
        195                 200                 205             


Lys Leu Thr Lys Ile Ile Cys Ala Gln Gln Cys Ser Gly Arg Cys Arg 
    210                 215                 220                 


Gly Lys Ser Pro Ser Asp Cys Cys His Asn Gln Cys Ala Ala Gly Cys 
225                 230                 235                 240 


Thr Gly Pro Arg Glu Ser Asp Cys Leu Val Cys Arg Lys Phe Arg Asp 
                245                 250                 255     


Glu Ala Thr Cys Lys Asp Thr Cys Pro Pro Leu Met Leu Tyr Asn Pro 
            260                 265                 270         


Thr Thr Tyr Gln Met Asp Val Asn Pro Glu Gly Lys Tyr Ser Phe Gly 
        275                 280                 285             


Ala Thr Cys Val Lys Lys Cys Pro Arg Asn Tyr Val Val Thr Asp His 
    290                 295                 300                 


Gly Ser Cys Val Arg Ala Cys Gly Ala Asp Ser Tyr Glu Met Glu Glu 
305                 310                 315                 320 


Asp Gly Val Arg Lys Cys Lys Lys Cys Glu Gly Pro Cys Arg Lys Val 
                325                 330                 335     


Cys Asn Gly Ile Gly Ile Gly Glu Phe Lys Asp Ser Leu Ser Ile Asn 
            340                 345                 350         


Ala Thr Asn Ile Lys His Phe Lys Asn Cys Thr Ser Ile Ser Gly Asp 
        355                 360                 365             


Leu His Ile Leu Pro Val Ala Phe Arg Gly Asp Ser Phe Thr His Thr 
    370                 375                 380                 


Pro Pro Leu Asp Pro Gln Glu Leu Asp Ile Leu Lys Thr Val Lys Glu 
385                 390                 395                 400 


Ile Thr Gly Leu Ser 
                405 


<210>  4897
<211>  705
<212>  PRT
<213>  homo sapiens

<400>  4897

Met Arg Pro Ser Gly Thr Ala Gly Ala Ala Leu Leu Ala Leu Leu Ala 
1               5                   10                  15      


Ala Leu Cys Pro Ala Ser Arg Ala Leu Glu Glu Lys Lys Val Cys Gln 
            20                  25                  30          


Gly Thr Ser Asn Lys Leu Thr Gln Leu Gly Thr Phe Glu Asp His Phe 
        35                  40                  45              


Leu Ser Leu Gln Arg Met Phe Asn Asn Cys Glu Val Val Leu Gly Asn 
    50                  55                  60                  


Leu Glu Ile Thr Tyr Val Gln Arg Asn Tyr Asp Leu Ser Phe Leu Lys 
65                  70                  75                  80  


Thr Ile Gln Glu Val Ala Gly Tyr Val Leu Ile Ala Leu Asn Thr Val 
                85                  90                  95      


Glu Arg Ile Pro Leu Glu Asn Leu Gln Ile Ile Arg Gly Asn Met Tyr 
            100                 105                 110         


Tyr Glu Asn Ser Tyr Ala Leu Ala Val Leu Ser Asn Tyr Asp Ala Asn 
        115                 120                 125             


Lys Thr Gly Leu Lys Glu Leu Pro Met Arg Asn Leu Gln Glu Ile Leu 
    130                 135                 140                 


His Gly Ala Val Arg Phe Ser Asn Asn Pro Ala Leu Cys Asn Val Glu 
145                 150                 155                 160 


Ser Ile Gln Trp Arg Asp Ile Val Ser Ser Asp Phe Leu Ser Asn Met 
                165                 170                 175     


Ser Met Asp Phe Gln Asn His Leu Gly Ser Cys Gln Lys Cys Asp Pro 
            180                 185                 190         


Ser Cys Pro Asn Gly Ser Cys Trp Gly Ala Gly Glu Glu Asn Cys Gln 
        195                 200                 205             


Lys Leu Thr Lys Ile Ile Cys Ala Gln Gln Cys Ser Gly Arg Cys Arg 
    210                 215                 220                 


Gly Lys Ser Pro Ser Asp Cys Cys His Asn Gln Cys Ala Ala Gly Cys 
225                 230                 235                 240 


Thr Gly Pro Arg Glu Ser Asp Cys Leu Val Cys Arg Lys Phe Arg Asp 
                245                 250                 255     


Glu Ala Thr Cys Lys Asp Thr Cys Pro Pro Leu Met Leu Tyr Asn Pro 
            260                 265                 270         


Thr Thr Tyr Gln Met Asp Val Asn Pro Glu Gly Lys Tyr Ser Phe Gly 
        275                 280                 285             


Ala Thr Cys Val Lys Lys Cys Pro Arg Asn Tyr Val Val Thr Asp His 
    290                 295                 300                 


Gly Ser Cys Val Arg Ala Cys Gly Ala Asp Ser Tyr Glu Met Glu Glu 
305                 310                 315                 320 


Asp Gly Val Arg Lys Cys Lys Lys Cys Glu Gly Pro Cys Arg Lys Val 
                325                 330                 335     


Cys Asn Gly Ile Gly Ile Gly Glu Phe Lys Asp Ser Leu Ser Ile Asn 
            340                 345                 350         


Ala Thr Asn Ile Lys His Phe Lys Asn Cys Thr Ser Ile Ser Gly Asp 
        355                 360                 365             


Leu His Ile Leu Pro Val Ala Phe Arg Gly Asp Ser Phe Thr His Thr 
    370                 375                 380                 


Pro Pro Leu Asp Pro Gln Glu Leu Asp Ile Leu Lys Thr Val Lys Glu 
385                 390                 395                 400 


Ile Thr Gly Phe Leu Leu Ile Gln Ala Trp Pro Glu Asn Arg Thr Asp 
                405                 410                 415     


Leu His Ala Phe Glu Asn Leu Glu Ile Ile Arg Gly Arg Thr Lys Gln 
            420                 425                 430         


His Gly Gln Phe Ser Leu Ala Val Val Ser Leu Asn Ile Thr Ser Leu 
        435                 440                 445             


Gly Leu Arg Ser Leu Lys Glu Ile Ser Asp Gly Asp Val Ile Ile Ser 
    450                 455                 460                 


Gly Asn Lys Asn Leu Cys Tyr Ala Asn Thr Ile Asn Trp Lys Lys Leu 
465                 470                 475                 480 


Phe Gly Thr Ser Gly Gln Lys Thr Lys Ile Ile Ser Asn Arg Gly Glu 
                485                 490                 495     


Asn Ser Cys Lys Ala Thr Gly Gln Val Cys His Ala Leu Cys Ser Pro 
            500                 505                 510         


Glu Gly Cys Trp Gly Pro Glu Pro Arg Asp Cys Val Ser Cys Arg Asn 
        515                 520                 525             


Val Ser Arg Gly Arg Glu Cys Val Asp Lys Cys Asn Leu Leu Glu Gly 
    530                 535                 540                 


Glu Pro Arg Glu Phe Val Glu Asn Ser Glu Cys Ile Gln Cys His Pro 
545                 550                 555                 560 


Glu Cys Leu Pro Gln Ala Met Asn Ile Thr Cys Thr Gly Arg Gly Pro 
                565                 570                 575     


Asp Asn Cys Ile Gln Cys Ala His Tyr Ile Asp Gly Pro His Cys Val 
            580                 585                 590         


Lys Thr Cys Pro Ala Gly Val Met Gly Glu Asn Asn Thr Leu Val Trp 
        595                 600                 605             


Lys Tyr Ala Asp Ala Gly His Val Cys His Leu Cys His Pro Asn Cys 
    610                 615                 620                 


Thr Tyr Gly Pro Gly Asn Glu Ser Leu Lys Ala Met Leu Phe Cys Leu 
625                 630                 635                 640 


Phe Lys Leu Ser Ser Cys Asn Gln Ser Asn Asp Gly Ser Val Ser His 
                645                 650                 655     


Gln Ser Gly Ser Pro Ala Ala Gln Glu Ser Cys Leu Gly Trp Ile Pro 
            660                 665                 670         


Ser Leu Leu Pro Ser Glu Phe Gln Leu Gly Trp Gly Gly Cys Ser His 
        675                 680                 685             


Leu His Ala Trp Pro Ser Ala Ser Val Ile Ile Thr Ala Ser Ser Cys 
    690                 695                 700                 


His 
705 


<210>  4898
<211>  420
<212>  PRT
<213>  homo sapiens

<400>  4898

Met Met Tyr Ser Pro Ile Cys Leu Thr Gln Asp Glu Phe His Pro Phe 
1               5                   10                  15      


Ile Glu Ala Leu Leu Pro His Val Arg Ala Ile Ala Tyr Thr Trp Phe 
            20                  25                  30          


Asn Leu Gln Ala Arg Lys Arg Lys Tyr Phe Lys Lys His Glu Lys Arg 
        35                  40                  45              


Met Ser Lys Asp Glu Glu Arg Ala Val Lys Asp Glu Leu Leu Ser Glu 
    50                  55                  60                  


Lys Pro Glu Ile Lys Gln Lys Trp Ala Ser Arg Leu Leu Ala Lys Leu 
65                  70                  75                  80  


Arg Lys Asp Ile Arg Gln Glu Tyr Arg Glu Asp Phe Val Leu Thr Val 
                85                  90                  95      


Thr Gly Lys Lys His Pro Cys Cys Val Leu Ser Asn Pro Asp Gln Lys 
            100                 105                 110         


Gly Lys Ile Arg Arg Ile Asp Cys Leu Arg Gln Ala Asp Lys Val Trp 
        115                 120                 125             


Arg Leu Asp Leu Val Met Val Ile Leu Phe Lys Gly Ile Pro Leu Glu 
    130                 135                 140                 


Ser Thr Asp Gly Glu Arg Leu Met Lys Ser Pro His Cys Thr Asn Pro 
145                 150                 155                 160 


Ala Leu Cys Val Gln Pro His His Ile Thr Val Ser Val Lys Glu Leu 
                165                 170                 175     


Asp Leu Phe Leu Ala Tyr Tyr Val Gln Glu Gln Asp Ser Gly Gln Ser 
            180                 185                 190         


Gly Ser Pro Ser His Asn Asp Pro Ala Lys Asn Pro Pro Gly Tyr Leu 
        195                 200                 205             


Glu Asp Ser Phe Val Lys Ser Gly Val Phe Asn Val Ser Glu Leu Val 
    210                 215                 220                 


Arg Val Ser Arg Thr Pro Ile Thr Gln Gly Thr Gly Val Asn Phe Pro 
225                 230                 235                 240 


Ile Gly Glu Ile Pro Ser Gln Pro Tyr Tyr His Asp Met Asn Ser Gly 
                245                 250                 255     


Val Asn Leu Gln Arg Ser Leu Ser Ser Pro Pro Ser Ser Lys Arg Pro 
            260                 265                 270         


Lys Thr Ile Ser Ile Asp Glu Asn Met Glu Pro Ser Pro Thr Gly Asp 
        275                 280                 285             


Phe Tyr Pro Ser Pro Ser Ser Pro Ala Ala Gly Ser Arg Thr Trp His 
    290                 295                 300                 


Glu Arg Asp Gln Asp Met Ser Ser Pro Thr Thr Met Lys Lys Pro Glu 
305                 310                 315                 320 


Lys Pro Leu Phe Ser Ser Ala Ser Pro Gln Asp Ser Ser Pro Arg Leu 
                325                 330                 335     


Ser Thr Phe Pro Gln His His His Pro Gly Ile Pro Gly Val Ala His 
            340                 345                 350         


Ser Val Ile Ser Thr Arg Thr Pro Pro Pro Pro Ser Pro Leu Pro Phe 
        355                 360                 365             


Pro Thr Gln Ala Ile Leu Pro Pro Ala Pro Ser Ser Tyr Phe Ser His 
    370                 375                 380                 


Pro Thr Ile Arg Tyr Pro Pro His Leu Asn Pro Gln Asp Thr Leu Lys 
385                 390                 395                 400 


Asn Tyr Val Pro Ser Tyr Asp Pro Ser Ser Pro Gln Thr Ser Gln Ser 
                405                 410                 415     


Trp Tyr Leu Gly 
            420 


<210>  4899
<211>  92
<212>  PRT
<213>  homo sapiens

<400>  4899

Met Ser Glu Leu Glu Lys Ala Met Val Ala Leu Ile Asp Val Phe His 
1               5                   10                  15      


Gln Tyr Ser Gly Arg Glu Gly Asp Lys His Lys Leu Lys Lys Ser Glu 
            20                  25                  30          


Leu Lys Glu Leu Ile Asn Asn Glu Leu Ser His Phe Leu Glu Glu Ile 
        35                  40                  45              


Lys Glu Gln Glu Val Val Asp Lys Val Met Glu Thr Leu Asp Asn Asp 
    50                  55                  60                  


Gly Asp Gly Glu Cys Asp Phe Gln Glu Phe Met Ala Phe Val Ala Met 
65                  70                  75                  80  


Val Thr Thr Ala Cys His Glu Phe Phe Glu His Glu 
                85                  90          


<210>  4900
<211>  391
<212>  PRT
<213>  homo sapiens

<400>  4900

Met Tyr Ser Met Met Met Glu Thr Asp Leu His Ser Pro Gly Gly Ala 
1               5                   10                  15      


Gln Ala Pro Thr Asn Leu Ser Gly Pro Ala Gly Ala Gly Gly Gly Gly 
            20                  25                  30          


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Lys Ala Asn Gln 
        35                  40                  45              


Asp Arg Val Lys Arg Pro Met Asn Ala Phe Met Val Trp Ser Arg Gly 
    50                  55                  60                  


Gln Arg Arg Lys Met Ala Gln Glu Asn Pro Lys Met His Asn Ser Glu 
65                  70                  75                  80  


Ile Ser Lys Arg Leu Gly Ala Glu Trp Lys Val Met Ser Glu Ala Glu 
                85                  90                  95      


Lys Arg Pro Phe Ile Asp Glu Ala Lys Arg Leu Arg Ala Leu His Met 
            100                 105                 110         


Lys Glu His Pro Asp Tyr Lys Tyr Arg Pro Arg Arg Lys Thr Lys Thr 
        115                 120                 125             


Leu Leu Lys Lys Asp Lys Tyr Ser Leu Ala Gly Gly Leu Leu Ala Ala 
    130                 135                 140                 


Gly Ala Gly Gly Gly Gly Ala Ala Val Ala Met Gly Val Gly Val Gly 
145                 150                 155                 160 


Val Gly Ala Ala Ala Val Gly Gln Arg Leu Glu Ser Pro Gly Gly Ala 
                165                 170                 175     


Ala Gly Gly Gly Tyr Ala His Val Asn Gly Trp Ala Asn Gly Ala Tyr 
            180                 185                 190         


Pro Gly Ser Val Ala Ala Ala Ala Ala Ala Ala Ala Met Met Gln Glu 
        195                 200                 205             


Ala Gln Leu Ala Tyr Gly Gln His Pro Gly Ala Gly Gly Ala His Pro 
    210                 215                 220                 


His Ala His Pro Ala His Pro His Pro His His Pro His Ala His Pro 
225                 230                 235                 240 


His Asn Pro Gln Pro Met His Arg Tyr Asp Met Gly Ala Leu Gln Tyr 
                245                 250                 255     


Ser Pro Ile Ser Asn Ser Gln Gly Tyr Met Ser Ala Ser Pro Ser Gly 
            260                 265                 270         


Tyr Gly Gly Leu Pro Tyr Gly Ala Ala Ala Ala Ala Ala Ala Ala Ala 
        275                 280                 285             


Gly Gly Ala His Gln Asn Ser Ala Val Ala Ala Ala Ala Ala Ala Ala 
    290                 295                 300                 


Ala Ala Ser Ser Gly Ala Leu Gly Ala Leu Gly Ser Leu Val Lys Ser 
305                 310                 315                 320 


Glu Pro Ser Gly Ser Pro Pro Ala Pro Ala His Ser Arg Ala Pro Cys 
                325                 330                 335     


Pro Gly Asp Leu Arg Glu Met Ile Ser Met Tyr Leu Pro Ala Gly Glu 
            340                 345                 350         


Gly Gly Asp Pro Ala Ala Ala Ala Ala Ala Ala Ala Gln Ser Arg Leu 
        355                 360                 365             


His Ser Leu Pro Gln His Tyr Gln Gly Ala Gly Ala Gly Val Asn Gly 
    370                 375                 380                 


Thr Val Pro Leu Thr His Ile 
385                 390     


<210>  4901
<211>  317
<212>  PRT
<213>  homo sapiens

<400>  4901

Met Tyr Asn Met Met Glu Thr Glu Leu Lys Pro Pro Gly Pro Gln Gln 
1               5                   10                  15      


Thr Ser Gly Gly Gly Gly Gly Asn Ser Thr Ala Ala Ala Ala Gly Gly 
            20                  25                  30          


Asn Gln Lys Asn Ser Pro Asp Arg Val Lys Arg Pro Met Asn Ala Phe 
        35                  40                  45              


Met Val Trp Ser Arg Gly Gln Arg Arg Lys Met Ala Gln Glu Asn Pro 
    50                  55                  60                  


Lys Met His Asn Ser Glu Ile Ser Lys Arg Leu Gly Ala Glu Trp Lys 
65                  70                  75                  80  


Leu Leu Ser Glu Thr Glu Lys Arg Pro Phe Ile Asp Glu Ala Lys Arg 
                85                  90                  95      


Leu Arg Ala Leu His Met Lys Glu His Pro Asp Tyr Lys Tyr Arg Pro 
            100                 105                 110         


Arg Arg Lys Thr Lys Thr Leu Met Lys Lys Asp Lys Tyr Thr Leu Pro 
        115                 120                 125             


Gly Gly Leu Leu Ala Pro Gly Gly Asn Ser Met Ala Ser Gly Val Gly 
    130                 135                 140                 


Val Gly Ala Gly Leu Gly Ala Gly Val Asn Gln Arg Met Asp Ser Tyr 
145                 150                 155                 160 


Ala His Met Asn Gly Trp Ser Asn Gly Ser Tyr Ser Met Met Gln Asp 
                165                 170                 175     


Gln Leu Gly Tyr Pro Gln His Pro Gly Leu Asn Ala His Gly Ala Ala 
            180                 185                 190         


Gln Met Gln Pro Met His Arg Tyr Asp Val Ser Ala Leu Gln Tyr Asn 
        195                 200                 205             


Ser Met Thr Ser Ser Gln Thr Tyr Met Asn Gly Ser Pro Thr Tyr Ser 
    210                 215                 220                 


Met Ser Tyr Ser Gln Gln Gly Thr Pro Gly Met Ala Leu Gly Ser Met 
225                 230                 235                 240 


Gly Ser Val Val Lys Ser Glu Ala Ser Ser Ser Pro Pro Val Val Thr 
                245                 250                 255     


Ser Ser Ser His Ser Arg Ala Pro Cys Gln Ala Gly Asp Leu Arg Asp 
            260                 265                 270         


Met Ile Ser Met Tyr Leu Pro Gly Ala Glu Val Pro Glu Pro Ala Ala 
        275                 280                 285             


Pro Ser Arg Leu His Met Ser Gln His Tyr Gln Ser Gly Pro Val Pro 
    290                 295                 300                 


Gly Thr Ala Ile Asn Gly Thr Leu Pro Leu Ser His Met 
305                 310                 315         


<210>  4902
<211>  542
<212>  PRT
<213>  homo sapiens

<400>  4902

Met Thr Lys Ser Asn Gly Glu Glu Pro Lys Met Gly Gly Arg Met Glu 
1               5                   10                  15      


Arg Phe Gln Gln Gly Val Arg Lys Arg Thr Leu Leu Ala Lys Lys Lys 
            20                  25                  30          


Val Gln Asn Ile Thr Lys Glu Asp Val Lys Ser Tyr Leu Phe Arg Asn 
        35                  40                  45              


Ala Phe Val Leu Leu Thr Val Thr Ala Val Ile Val Gly Thr Ile Leu 
    50                  55                  60                  


Gly Phe Thr Leu Arg Pro Tyr Arg Met Ser Tyr Arg Glu Val Lys Tyr 
65                  70                  75                  80  


Phe Ser Phe Pro Gly Glu Leu Leu Met Arg Met Leu Gln Met Leu Val 
                85                  90                  95      


Leu Pro Leu Ile Ile Ser Ser Leu Val Thr Gly Met Ala Ala Leu Asp 
            100                 105                 110         


Ser Lys Ala Ser Gly Lys Met Gly Met Arg Ala Val Val Tyr Tyr Met 
        115                 120                 125             


Thr Thr Thr Ile Ile Ala Val Val Ile Gly Ile Ile Ile Val Ile Ile 
    130                 135                 140                 


Ile His Pro Gly Lys Gly Thr Lys Glu Asn Met His Arg Glu Gly Lys 
145                 150                 155                 160 


Ile Val Arg Val Thr Ala Ala Asp Ala Phe Leu Asp Leu Ile Arg Asn 
                165                 170                 175     


Met Phe Pro Pro Asn Leu Val Glu Ala Cys Phe Lys Gln Phe Lys Thr 
            180                 185                 190         


Asn Tyr Glu Lys Arg Ser Phe Lys Val Pro Ile Gln Ala Asn Glu Thr 
        195                 200                 205             


Leu Val Gly Ala Val Ile Asn Asn Val Ser Glu Ala Met Glu Thr Leu 
    210                 215                 220                 


Thr Arg Ile Thr Glu Glu Leu Val Pro Val Pro Gly Ser Val Asn Gly 
225                 230                 235                 240 


Val Asn Ala Leu Gly Leu Val Val Phe Ser Met Cys Phe Gly Phe Val 
                245                 250                 255     


Ile Gly Asn Met Lys Glu Gln Gly Gln Ala Leu Arg Glu Phe Phe Asp 
            260                 265                 270         


Ser Leu Asn Glu Ala Ile Met Arg Leu Val Ala Val Ile Met Trp Tyr 
        275                 280                 285             


Ala Pro Val Gly Ile Leu Phe Leu Ile Ala Gly Lys Ile Val Glu Met 
    290                 295                 300                 


Glu Asp Met Gly Val Ile Gly Gly Gln Leu Ala Met Tyr Thr Val Thr 
305                 310                 315                 320 


Val Ile Val Gly Leu Leu Ile His Ala Val Ile Val Leu Pro Leu Leu 
                325                 330                 335     


Tyr Phe Leu Val Thr Arg Lys Asn Pro Trp Val Phe Ile Gly Gly Leu 
            340                 345                 350         


Leu Gln Ala Leu Ile Thr Ala Leu Gly Thr Ser Ser Ser Ser Ala Thr 
        355                 360                 365             


Leu Pro Ile Thr Phe Lys Cys Leu Glu Glu Asn Asn Gly Val Asp Lys 
    370                 375                 380                 


Arg Val Thr Arg Phe Val Leu Pro Val Gly Ala Thr Ile Asn Met Asp 
385                 390                 395                 400 


Gly Thr Ala Leu Tyr Glu Ala Leu Ala Ala Ile Phe Ile Ala Gln Val 
                405                 410                 415     


Asn Asn Phe Glu Leu Asn Phe Gly Gln Ile Ile Thr Ile Ser Ile Thr 
            420                 425                 430         


Ala Thr Ala Ala Ser Ile Gly Ala Ala Gly Ile Pro Gln Ala Gly Leu 
        435                 440                 445             


Val Thr Met Val Ile Val Leu Thr Ser Val Gly Leu Pro Thr Asp Asp 
    450                 455                 460                 


Ile Thr Leu Ile Ile Ala Val Asp Trp Phe Leu Asp Arg Leu Arg Thr 
465                 470                 475                 480 


Thr Thr Asn Val Leu Gly Asp Ser Leu Gly Ala Gly Ile Val Glu His 
                485                 490                 495     


Leu Ser Arg His Glu Leu Lys Asn Arg Asp Val Glu Met Gly Asn Ser 
            500                 505                 510         


Val Ile Glu Glu Asn Glu Met Lys Lys Pro Tyr Gln Leu Ile Ala Gln 
        515                 520                 525             


Asp Asn Glu Thr Glu Lys Pro Ile Asp Ser Glu Thr Lys Met 
    530                 535                 540         


<210>  4903
<211>  497
<212>  PRT
<213>  homo sapiens

<400>  4903

Met Thr Lys Ser Asn Gly Glu Glu Pro Lys Met Gly Gly Arg Met Glu 
1               5                   10                  15      


Arg Phe Gln Gln Gly Val Arg Lys Arg Thr Leu Leu Ala Lys Lys Lys 
            20                  25                  30          


Val Gln Asn Ile Thr Lys Glu Asp Val Lys Ser Tyr Leu Phe Arg Asn 
        35                  40                  45              


Ala Phe Val Leu Leu Thr Val Thr Ala Val Ile Val Gly Thr Ile Leu 
    50                  55                  60                  


Gly Phe Thr Leu Arg Pro Tyr Arg Met Ser Tyr Arg Glu Val Lys Tyr 
65                  70                  75                  80  


Phe Ser Phe Pro Gly Glu Leu Leu Met Arg Met Leu Gln Met Leu Val 
                85                  90                  95      


Leu Pro Leu Ile Ile Ser Ser Leu Val Thr Gly Met Ala Ala Leu Asp 
            100                 105                 110         


Ser Lys Ala Ser Gly Lys Met Gly Met Arg Ala Val Val Tyr Tyr Met 
        115                 120                 125             


Thr Thr Thr Ile Ile Ala Val Val Ile Gly Ile Ile Ile Val Ile Ile 
    130                 135                 140                 


Ile His Pro Gly Lys Gly Thr Lys Glu Asn Met His Arg Glu Gly Lys 
145                 150                 155                 160 


Ile Val Arg Val Thr Ala Ala Asp Ala Phe Leu Asp Leu Ile Arg Asn 
                165                 170                 175     


Met Phe Pro Pro Asn Leu Val Glu Ala Cys Phe Lys Gln Phe Lys Thr 
            180                 185                 190         


Asn Tyr Glu Lys Arg Ser Phe Lys Val Pro Ile Gln Ala Asn Glu Thr 
        195                 200                 205             


Leu Val Gly Ala Val Ile Asn Asn Val Ser Glu Ala Met Glu Thr Leu 
    210                 215                 220                 


Thr Arg Ile Thr Glu Glu Leu Val Pro Val Pro Gly Ser Val Asn Gly 
225                 230                 235                 240 


Val Asn Ala Leu Gly Leu Val Val Phe Ser Met Cys Phe Gly Phe Val 
                245                 250                 255     


Ile Gly Asn Met Lys Glu Gln Gly Gln Ala Leu Arg Glu Phe Phe Asp 
            260                 265                 270         


Ser Leu Asn Glu Ala Ile Met Arg Leu Val Ala Val Ile Met Trp Tyr 
        275                 280                 285             


Ala Pro Val Gly Ile Leu Phe Leu Ile Ala Gly Lys Ile Val Glu Met 
    290                 295                 300                 


Glu Asp Met Gly Val Ile Gly Gly Gln Leu Ala Met Tyr Thr Val Thr 
305                 310                 315                 320 


Val Ile Val Gly Leu Leu Ile His Ala Val Ile Val Leu Pro Leu Leu 
                325                 330                 335     


Tyr Phe Leu Val Thr Arg Lys Asn Pro Trp Val Phe Ile Gly Gly Leu 
            340                 345                 350         


Leu Gln Ala Leu Ile Thr Ala Leu Gly Thr Ser Ser Ser Ser Ala Thr 
        355                 360                 365             


Leu Pro Ile Thr Phe Lys Cys Leu Glu Glu Asn Asn Gly Val Asp Lys 
    370                 375                 380                 


Arg Val Thr Arg Phe Val Leu Pro Val Gly Ala Thr Ile Asn Met Asp 
385                 390                 395                 400 


Gly Thr Ala Leu Tyr Glu Ala Leu Ala Ala Ile Phe Ile Ala Gln Val 
                405                 410                 415     


Asn Asn Phe Glu Leu Asn Phe Gly Gln Ile Ile Thr Ile Arg Asp Arg 
            420                 425                 430         


Leu Arg Thr Thr Thr Asn Val Leu Gly Asp Ser Leu Gly Ala Gly Ile 
        435                 440                 445             


Val Glu His Leu Ser Arg His Glu Leu Lys Asn Arg Asp Val Glu Met 
    450                 455                 460                 


Gly Asn Ser Val Ile Glu Glu Asn Glu Met Lys Lys Pro Tyr Gln Leu 
465                 470                 475                 480 


Ile Ala Gln Asp Asn Glu Thr Glu Lys Pro Ile Asp Ser Glu Thr Lys 
                485                 490                 495     


Met 
    


<210>  4904
<211>  65
<212>  PRT
<213>  homo sapiens

<400>  4904

Met Thr Lys Ser Asn Gly Glu Glu Pro Lys Met Gly Gly Arg Met Glu 
1               5                   10                  15      


Arg Phe Gln Gln Gly Val Arg Lys Arg Thr Leu Leu Ala Lys Lys Lys 
            20                  25                  30          


Val Gln Asn Ile Thr Lys Glu Asp Val Lys Ser Tyr Leu Phe Arg Asn 
        35                  40                  45              


Ala Phe Val Leu Leu Thr Val Thr Ala Val Ile Val Gly Glu Ser Phe 
    50                  55                  60                  


Asp 
65  


<210>  4905
<211>  673
<212>  PRT
<213>  homo sapiens

<400>  4905

Met Asp Leu Thr Lys Met Gly Met Ile Gln Leu Gln Asn Pro Ser His 
1               5                   10                  15      


Pro Thr Gly Leu Leu Cys Lys Ala Asn Gln Met Arg Leu Ala Gly Thr 
            20                  25                  30          


Leu Cys Asp Val Val Ile Met Val Asp Ser Gln Glu Phe His Ala His 
        35                  40                  45              


Arg Thr Val Leu Ala Cys Thr Ser Lys Met Phe Glu Ile Leu Phe His 
    50                  55                  60                  


Arg Asn Ser Gln His Tyr Thr Leu Asp Phe Leu Ser Pro Lys Thr Phe 
65                  70                  75                  80  


Gln Gln Ile Leu Glu Tyr Ala Tyr Thr Ala Thr Leu Gln Ala Lys Ala 
                85                  90                  95      


Glu Asp Leu Asp Asp Leu Leu Tyr Ala Ala Glu Ile Leu Glu Ile Glu 
            100                 105                 110         


Tyr Leu Glu Glu Gln Cys Leu Lys Met Leu Glu Thr Ile Gln Ala Ser 
        115                 120                 125             


Asp Asp Asn Asp Thr Glu Ala Thr Met Ala Asp Gly Gly Ala Glu Glu 
    130                 135                 140                 


Glu Glu Asp Arg Lys Ala Arg Tyr Leu Lys Asn Ile Phe Ile Ser Lys 
145                 150                 155                 160 


His Ser Ser Glu Glu Ser Gly Tyr Ala Ser Val Ala Gly Gln Ser Leu 
                165                 170                 175     


Pro Gly Pro Met Val Asp Gln Ser Pro Ser Val Ser Thr Ser Phe Gly 
            180                 185                 190         


Leu Ser Ala Met Ser Pro Thr Lys Ala Ala Val Asp Ser Leu Met Thr 
        195                 200                 205             


Ile Gly Gln Ser Leu Leu Gln Gly Thr Leu Gln Pro Pro Ala Gly Pro 
    210                 215                 220                 


Glu Glu Pro Thr Leu Ala Gly Gly Gly Arg His Pro Gly Val Ala Glu 
225                 230                 235                 240 


Val Lys Thr Glu Met Met Gln Val Asp Glu Val Pro Ser Gln Asp Ser 
                245                 250                 255     


Pro Gly Ala Ala Glu Ser Ser Ile Ser Gly Gly Met Gly Asp Lys Val 
            260                 265                 270         


Glu Glu Arg Gly Lys Glu Gly Pro Gly Thr Pro Thr Arg Ser Ser Val 
        275                 280                 285             


Ile Thr Ser Ala Arg Glu Leu His Tyr Gly Arg Glu Glu Ser Ala Glu 
    290                 295                 300                 


Gln Val Pro Pro Pro Ala Glu Ala Gly Gln Ala Pro Thr Gly Arg Pro 
305                 310                 315                 320 


Glu His Pro Ala Pro Pro Pro Glu Lys His Leu Gly Ile Tyr Ser Val 
                325                 330                 335     


Leu Pro Asn His Lys Ala Asp Ala Val Leu Ser Met Pro Ser Ser Val 
            340                 345                 350         


Thr Ser Gly Leu His Val Gln Pro Ala Leu Ala Val Ser Met Asp Phe 
        355                 360                 365             


Ser Thr Tyr Gly Gly Leu Leu Pro Gln Gly Phe Ile Gln Arg Glu Leu 
    370                 375                 380                 


Phe Ser Lys Leu Gly Glu Leu Ala Val Gly Met Lys Ser Glu Ser Arg 
385                 390                 395                 400 


Thr Ile Gly Glu Gln Cys Ser Val Cys Gly Val Glu Leu Pro Asp Asn 
                405                 410                 415     


Glu Ala Val Glu Gln His Arg Lys Leu His Ser Gly Met Lys Thr Tyr 
            420                 425                 430         


Gly Cys Glu Leu Cys Gly Lys Arg Phe Leu Asp Ser Leu Arg Leu Arg 
        435                 440                 445             


Met His Leu Leu Ala His Ser Ala Gly Ala Lys Ala Phe Val Cys Asp 
    450                 455                 460                 


Gln Cys Gly Ala Gln Phe Ser Lys Glu Asp Ala Leu Glu Thr His Arg 
465                 470                 475                 480 


Gln Thr His Thr Gly Thr Asp Met Ala Val Phe Cys Leu Leu Cys Gly 
                485                 490                 495     


Lys Arg Phe Gln Ala Gln Ser Ala Leu Gln Gln His Met Glu Val His 
            500                 505                 510         


Ala Gly Val Arg Ser Tyr Ile Cys Ser Glu Cys Asn Arg Thr Phe Pro 
        515                 520                 525             


Ser His Thr Ala Leu Lys Arg His Leu Arg Ser His Thr Gly Asp His 
    530                 535                 540                 


Pro Tyr Glu Cys Glu Phe Cys Gly Ser Cys Phe Arg Asp Glu Ser Thr 
545                 550                 555                 560 


Leu Lys Ser His Lys Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys 
                565                 570                 575     


Asn Gly Cys Gly Lys Lys Phe Ser Leu Lys His Gln Leu Glu Thr His 
            580                 585                 590         


Tyr Arg Val His Thr Gly Glu Lys Pro Phe Glu Cys Lys Leu Cys His 
        595                 600                 605             


Gln Arg Ser Arg Asp Tyr Ser Ala Met Ile Lys His Leu Arg Thr His 
    610                 615                 620                 


Asn Gly Ala Ser Pro Tyr Gln Cys Thr Ile Cys Thr Glu Tyr Cys Pro 
625                 630                 635                 640 


Ser Leu Ser Ser Met Gln Lys His Met Lys Gly His Lys Pro Glu Glu 
                645                 650                 655     


Ile Pro Pro Asp Trp Arg Ile Glu Lys Thr Tyr Leu Tyr Leu Cys Tyr 
            660                 665                 670         


Val 
    


<210>  4906
<211>  673
<212>  PRT
<213>  homo sapiens

<400>  4906

Met Asp Leu Thr Lys Met Gly Met Ile Gln Leu Gln Asn Pro Ser His 
1               5                   10                  15      


Pro Thr Gly Leu Leu Cys Lys Ala Asn Gln Met Arg Leu Ala Gly Thr 
            20                  25                  30          


Leu Cys Asp Val Val Ile Met Val Asp Ser Gln Glu Phe His Ala His 
        35                  40                  45              


Arg Thr Val Leu Ala Cys Thr Ser Lys Met Phe Glu Ile Leu Phe His 
    50                  55                  60                  


Arg Asn Ser Gln His Tyr Thr Leu Asp Phe Leu Ser Pro Lys Thr Phe 
65                  70                  75                  80  


Gln Gln Ile Leu Glu Tyr Ala Tyr Thr Ala Thr Leu Gln Ala Lys Ala 
                85                  90                  95      


Glu Asp Leu Asp Asp Leu Leu Tyr Ala Ala Glu Ile Leu Glu Ile Glu 
            100                 105                 110         


Tyr Leu Glu Glu Gln Cys Leu Lys Met Leu Glu Thr Ile Gln Ala Ser 
        115                 120                 125             


Asp Asp Asn Asp Thr Glu Ala Thr Met Ala Asp Gly Gly Ala Glu Glu 
    130                 135                 140                 


Glu Glu Asp Arg Lys Ala Arg Tyr Leu Lys Asn Ile Phe Ile Ser Lys 
145                 150                 155                 160 


His Ser Ser Glu Glu Ser Gly Tyr Ala Ser Val Ala Gly Gln Ser Leu 
                165                 170                 175     


Pro Gly Pro Met Val Asp Gln Ser Pro Ser Val Ser Thr Ser Phe Gly 
            180                 185                 190         


Leu Ser Ala Met Ser Pro Thr Lys Ala Ala Val Asp Ser Leu Met Thr 
        195                 200                 205             


Ile Gly Gln Ser Leu Leu Gln Gly Thr Leu Gln Pro Pro Ala Gly Pro 
    210                 215                 220                 


Glu Glu Pro Thr Leu Ala Gly Gly Gly Arg His Pro Gly Val Ala Glu 
225                 230                 235                 240 


Val Lys Thr Glu Met Met Gln Val Asp Glu Val Pro Ser Gln Asp Ser 
                245                 250                 255     


Pro Gly Ala Ala Glu Ser Ser Ile Ser Gly Gly Met Gly Asp Lys Val 
            260                 265                 270         


Glu Glu Arg Gly Lys Glu Gly Pro Gly Thr Pro Thr Arg Ser Ser Val 
        275                 280                 285             


Ile Thr Ser Ala Arg Glu Leu His Tyr Gly Arg Glu Glu Ser Ala Glu 
    290                 295                 300                 


Gln Val Pro Pro Pro Ala Glu Ala Gly Gln Ala Pro Thr Gly Arg Pro 
305                 310                 315                 320 


Glu His Pro Ala Pro Pro Pro Glu Lys His Leu Gly Ile Tyr Ser Val 
                325                 330                 335     


Leu Pro Asn His Lys Ala Asp Ala Val Leu Ser Met Pro Ser Ser Val 
            340                 345                 350         


Thr Ser Gly Leu His Val Gln Pro Ala Leu Ala Val Ser Met Asp Phe 
        355                 360                 365             


Ser Thr Tyr Gly Gly Leu Leu Pro Gln Gly Phe Ile Gln Arg Glu Leu 
    370                 375                 380                 


Phe Ser Lys Leu Gly Glu Leu Ala Val Gly Met Lys Ser Glu Ser Arg 
385                 390                 395                 400 


Thr Ile Gly Glu Gln Cys Ser Val Cys Gly Val Glu Leu Pro Asp Asn 
                405                 410                 415     


Glu Ala Val Glu Gln His Arg Lys Leu His Ser Gly Met Lys Thr Tyr 
            420                 425                 430         


Gly Cys Glu Leu Cys Gly Lys Arg Phe Leu Asp Ser Leu Arg Leu Arg 
        435                 440                 445             


Met His Leu Leu Ala His Ser Ala Gly Ala Lys Ala Phe Val Cys Asp 
    450                 455                 460                 


Gln Cys Gly Ala Gln Phe Ser Lys Glu Asp Ala Leu Glu Thr His Arg 
465                 470                 475                 480 


Gln Thr His Thr Gly Thr Asp Met Ala Val Phe Cys Leu Leu Cys Gly 
                485                 490                 495     


Lys Arg Phe Gln Ala Gln Ser Ala Leu Gln Gln His Met Glu Val His 
            500                 505                 510         


Ala Gly Val Arg Ser Tyr Ile Cys Ser Glu Cys Asn Arg Thr Phe Pro 
        515                 520                 525             


Ser His Thr Ala Leu Lys Arg His Leu Arg Ser His Thr Gly Asp His 
    530                 535                 540                 


Pro Tyr Glu Cys Glu Phe Cys Gly Ser Cys Phe Arg Asp Glu Ser Thr 
545                 550                 555                 560 


Leu Lys Ser His Lys Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys 
                565                 570                 575     


Asn Gly Cys Gly Lys Lys Phe Ser Leu Lys His Gln Leu Glu Thr His 
            580                 585                 590         


Tyr Arg Val His Thr Gly Glu Lys Pro Phe Glu Cys Lys Leu Cys His 
        595                 600                 605             


Gln Arg Ser Arg Asp Tyr Ser Ala Met Ile Lys His Leu Arg Thr His 
    610                 615                 620                 


Asn Gly Ala Ser Pro Tyr Gln Cys Thr Ile Cys Thr Glu Tyr Cys Pro 
625                 630                 635                 640 


Ser Leu Ser Ser Met Gln Lys His Met Lys Gly His Lys Pro Glu Glu 
                645                 650                 655     


Ile Pro Pro Asp Trp Arg Ile Glu Lys Thr Tyr Leu Tyr Leu Cys Tyr 
            660                 665                 670         


Val 
    


<210>  4907
<211>  1621
<212>  PRT
<213>  homo sapiens

<400>  4907

Met Glu Gly Cys Met Gly Glu Glu Ser Phe Gln Met Trp Glu Leu Asn 
1               5                   10                  15      


Arg Arg Leu Glu Ala Tyr Leu Ala Arg Val Lys Ala Leu Glu Glu Gln 
            20                  25                  30          


Asn Glu Leu Leu Ser Ala Glu Leu Gly Gly Leu Arg Ala Gln Ser Ala 
        35                  40                  45              


Asp Thr Ser Trp Arg Ala His Ala Asp Asp Glu Leu Ala Ala Leu Arg 
    50                  55                  60                  


Ala Leu Val Asp Gln Arg Trp Arg Glu Lys His Ala Ala Glu Val Ala 
65                  70                  75                  80  


Arg Asp Asn Leu Ala Glu Glu Leu Glu Gly Val Ala Gly Arg Cys Gln 
                85                  90                  95      


Gln Leu Arg Leu Ala Arg Glu Arg Thr Thr Glu Glu Val Ala Arg Asn 
            100                 105                 110         


Arg Arg Ala Val Glu Ala Glu Lys Cys Ala Arg Ala Trp Leu Ser Ser 
        115                 120                 125             


Gln Val Ala Glu Leu Glu Arg Glu Leu Glu Ala Leu Arg Val Ala His 
    130                 135                 140                 


Glu Glu Glu Arg Val Gly Leu Asn Ala Gln Ala Ala Cys Ala Pro Arg 
145                 150                 155                 160 


Cys Pro Ala Pro Pro Arg Gly Pro Pro Ala Pro Ala Pro Glu Val Glu 
                165                 170                 175     


Glu Leu Ala Arg Arg Leu Gly Glu Ala Trp Arg Gly Ala Val Arg Gly 
            180                 185                 190         


Tyr Gln Glu Arg Val Ala His Met Glu Thr Ser Leu Gly Gln Ala Arg 
        195                 200                 205             


Glu Arg Leu Gly Arg Ala Val Gln Gly Ala Arg Glu Gly Arg Leu Glu 
    210                 215                 220                 


Leu Gln Gln Leu Gln Ala Glu Arg Gly Gly Leu Leu Glu Arg Arg Ala 
225                 230                 235                 240 


Ala Leu Glu Gln Arg Leu Glu Gly Arg Trp Gln Glu Arg Leu Arg Ala 
                245                 250                 255     


Thr Glu Lys Phe Gln Leu Ala Val Glu Ala Leu Glu Gln Glu Lys Gln 
            260                 265                 270         


Gly Leu Gln Ser Gln Ile Ala Gln Val Leu Glu Gly Arg Gln Gln Leu 
        275                 280                 285             


Ala His Leu Lys Met Ser Leu Ser Leu Glu Val Ala Thr Tyr Arg Thr 
    290                 295                 300                 


Leu Leu Glu Ala Glu Asn Ser Arg Leu Gln Thr Pro Gly Gly Gly Ser 
305                 310                 315                 320 


Lys Thr Ser Leu Ser Phe Gln Asp Pro Lys Leu Glu Leu Gln Phe Pro 
                325                 330                 335     


Arg Thr Pro Glu Gly Arg Arg Leu Gly Ser Leu Leu Pro Val Leu Ser 
            340                 345                 350         


Pro Thr Ser Leu Pro Ser Pro Leu Pro Ala Thr Leu Glu Thr Pro Val 
        355                 360                 365             


Pro Ala Phe Leu Lys Asn Gln Glu Phe Leu Gln Ala Arg Thr Pro Thr 
    370                 375                 380                 


Leu Ala Ser Thr Pro Ile Pro Pro Thr Pro Gln Ala Pro Ser Pro Ala 
385                 390                 395                 400 


Val Asp Ala Glu Ile Arg Ala Gln Asp Ala Pro Leu Ser Leu Leu Gln 
                405                 410                 415     


Thr Gln Gly Gly Arg Lys Gln Ala Pro Glu Pro Leu Arg Ala Glu Ala 
            420                 425                 430         


Arg Val Ala Ile Pro Ala Ser Val Leu Pro Gly Pro Glu Glu Pro Gly 
        435                 440                 445             


Gly Gln Arg Gln Glu Ala Ser Thr Gly Gln Ser Pro Glu Asp His Ala 
    450                 455                 460                 


Ser Leu Ala Pro Pro Leu Ser Pro Asp His Ser Ser Leu Glu Ala Lys 
465                 470                 475                 480 


Asp Gly Glu Ser Gly Gly Ser Arg Val Phe Ser Ile Cys Arg Gly Glu 
                485                 490                 495     


Gly Glu Gly Gln Ile Trp Gly Leu Val Glu Lys Glu Thr Ala Ile Glu 
            500                 505                 510         


Gly Lys Val Val Ser Ser Leu Gln Gln Glu Ile Trp Glu Glu Glu Asp 
        515                 520                 525             


Leu Asn Arg Lys Glu Ile Gln Asp Ser Gln Val Pro Leu Glu Lys Glu 
    530                 535                 540                 


Thr Leu Lys Ser Leu Gly Glu Glu Ile Gln Glu Ser Leu Lys Thr Leu 
545                 550                 555                 560 


Glu Asn Gln Ser His Glu Thr Leu Glu Arg Glu Asn Gln Glu Cys Pro 
                565                 570                 575     


Arg Ser Leu Glu Glu Asp Leu Glu Thr Leu Lys Ser Leu Glu Lys Glu 
            580                 585                 590         


Asn Lys Glu Leu Leu Lys Asp Val Glu Val Val Arg Pro Leu Glu Lys 
        595                 600                 605             


Glu Ala Val Gly Gln Leu Lys Pro Thr Gly Lys Glu Asp Thr Gln Thr 
    610                 615                 620                 


Leu Gln Ser Leu Gln Lys Glu Asn Gln Glu Leu Met Lys Ser Leu Glu 
625                 630                 635                 640 


Gly Asn Leu Glu Thr Phe Leu Phe Pro Gly Thr Glu Asn Gln Glu Leu 
                645                 650                 655     


Val Ser Ser Leu Gln Glu Asn Leu Glu Ser Leu Thr Ala Leu Glu Lys 
            660                 665                 670         


Glu Asn Gln Glu Pro Leu Arg Ser Pro Glu Val Gly Asp Glu Glu Ala 
        675                 680                 685             


Leu Arg Pro Leu Thr Lys Glu Asn Gln Glu Pro Leu Arg Ser Leu Glu 
    690                 695                 700                 


Asp Glu Asn Lys Glu Ala Phe Arg Ser Leu Glu Lys Glu Asn Gln Glu 
705                 710                 715                 720 


Pro Leu Lys Thr Leu Glu Glu Glu Asp Gln Ser Ile Val Arg Pro Leu 
                725                 730                 735     


Glu Thr Glu Asn His Lys Ser Leu Arg Ser Leu Glu Glu Gln Asp Gln 
            740                 745                 750         


Glu Thr Leu Arg Thr Leu Glu Lys Glu Thr Gln Gln Arg Arg Arg Ser 
        755                 760                 765             


Leu Gly Glu Gln Asp Gln Met Thr Leu Arg Pro Pro Glu Lys Val Asp 
    770                 775                 780                 


Leu Glu Pro Leu Lys Ser Leu Asp Gln Glu Ile Ala Arg Pro Leu Glu 
785                 790                 795                 800 


Asn Glu Asn Gln Glu Phe Leu Lys Ser Leu Lys Glu Glu Ser Val Glu 
                805                 810                 815     


Ala Val Lys Ser Leu Glu Thr Glu Ile Leu Glu Ser Leu Lys Ser Ala 
            820                 825                 830         


Gly Gln Glu Asn Leu Glu Thr Leu Lys Ser Pro Glu Thr Gln Ala Pro 
        835                 840                 845             


Leu Trp Thr Pro Glu Glu Ile Asn Gln Gly Ala Met Asn Pro Leu Glu 
    850                 855                 860                 


Lys Glu Ile Gln Glu Pro Leu Glu Ser Val Glu Val Asn Gln Glu Thr 
865                 870                 875                 880 


Phe Arg Leu Leu Glu Glu Glu Asn Gln Glu Ser Leu Arg Ser Leu Gly 
                885                 890                 895     


Ala Trp Asn Leu Glu Asn Leu Arg Ser Pro Glu Glu Val Asp Lys Glu 
            900                 905                 910         


Ser Gln Arg Asn Leu Glu Glu Glu Glu Asn Leu Gly Lys Gly Glu Tyr 
        915                 920                 925             


Gln Glu Ser Leu Arg Ser Leu Glu Glu Glu Gly Gln Glu Leu Pro Gln 
    930                 935                 940                 


Ser Ala Asp Val Gln Arg Trp Glu Asp Thr Val Glu Lys Asp Gln Glu 
945                 950                 955                 960 


Leu Ala Gln Glu Ser Pro Pro Gly Met Ala Gly Val Glu Asn Glu Asp 
                965                 970                 975     


Glu Ala Glu Leu Asn Leu Arg Glu Gln Asp Gly Phe Thr Gly Lys Glu 
            980                 985                 990         


Glu Val Val Glu Gln Gly Glu Leu  Asn Ala Thr Glu Glu  Val Trp Ile 
        995                 1000                 1005             


Pro Gly  Glu Gly His Pro Glu  Ser Pro Glu Pro Lys  Glu Gln Arg 
    1010                 1015                 1020             


Gly Leu  Val Glu Gly Ala Ser  Val Lys Gly Gly Ala  Glu Gly Leu 
    1025                 1030                 1035             


Gln Asp  Pro Glu Gly Gln Ser  Gln Gln Val Gly Ala  Pro Gly Leu 
    1040                 1045                 1050             


Gln Ala  Pro Gln Gly Leu Pro  Glu Ala Ile Glu Pro  Leu Val Glu 
    1055                 1060                 1065             


Asp Asp  Val Ala Pro Gly Gly  Asp Gln Ala Ser Pro  Glu Val Met 
    1070                 1075                 1080             


Leu Gly  Ser Glu Pro Ala Met  Gly Glu Ser Ala Ala  Gly Ala Glu 
    1085                 1090                 1095             


Pro Gly  Pro Gly Gln Gly Val  Gly Gly Leu Gly Asp  Pro Gly His 
    1100                 1105                 1110             


Leu Thr  Arg Glu Glu Val Met  Glu Pro Pro Leu Glu  Glu Glu Ser 
    1115                 1120                 1125             


Leu Glu  Ala Lys Arg Val Gln  Gly Leu Glu Gly Pro  Arg Lys Asp 
    1130                 1135                 1140             


Leu Glu  Glu Ala Gly Gly Leu  Gly Thr Glu Phe Ser  Glu Leu Pro 
    1145                 1150                 1155             


Gly Lys  Ser Arg Asp Pro Trp  Glu Pro Pro Arg Glu  Gly Arg Glu 
    1160                 1165                 1170             


Glu Ser  Glu Ala Glu Ala Pro  Arg Gly Ala Glu Glu  Ala Phe Pro 
    1175                 1180                 1185             


Ala Glu  Thr Leu Gly His Thr  Gly Ser Asp Ala Pro  Ser Pro Trp 
    1190                 1195                 1200             


Pro Leu  Gly Ser Glu Glu Ala  Glu Glu Asp Val Pro  Pro Val Leu 
    1205                 1210                 1215             


Val Ser  Pro Ser Pro Thr Tyr  Thr Pro Ile Leu Glu  Asp Ala Pro 
    1220                 1225                 1230             


Gly Pro  Gln Pro Gln Ala Glu  Gly Ser Gln Glu Ala  Ser Trp Gly 
    1235                 1240                 1245             


Val Gln  Gly Arg Ala Glu Ala  Leu Gly Lys Val Glu  Ser Glu Gln 
    1250                 1255                 1260             


Glu Glu  Leu Gly Ser Gly Glu  Ile Pro Glu Gly Pro  Gln Glu Glu 
    1265                 1270                 1275             


Gly Glu  Glu Ser Arg Glu Glu  Ser Glu Glu Asp Glu  Leu Gly Glu 
    1280                 1285                 1290             


Thr Leu  Pro Asp Ser Thr Pro  Leu Gly Phe Tyr Leu  Arg Ser Pro 
    1295                 1300                 1305             


Thr Ser  Pro Arg Trp Asp Pro  Thr Gly Glu Gln Arg  Pro Pro Pro 
    1310                 1315                 1320             


Gln Gly  Glu Thr Gly Lys Glu  Gly Trp Asp Pro Ala  Val Leu Ala 
    1325                 1330                 1335             


Ser Glu  Gly Leu Glu Ala Pro  Pro Ser Glu Lys Glu  Glu Gly Glu 
    1340                 1345                 1350             


Glu Gly  Glu Glu Glu Cys Gly  Arg Asp Ser Asp Leu  Ser Glu Glu 
    1355                 1360                 1365             


Phe Glu  Asp Leu Gly Thr Glu  Ala Pro Phe Leu Pro  Gly Val Pro 
    1370                 1375                 1380             


Gly Glu  Val Ala Glu Pro Leu  Gly Gln Val Pro Gln  Leu Leu Leu 
    1385                 1390                 1395             


Asp Pro  Ala Ala Trp Asp Arg  Asp Gly Glu Ser Asp  Gly Phe Ala 
    1400                 1405                 1410             


Asp Glu  Glu Glu Ser Gly Glu  Glu Gly Glu Glu Asp  Gln Glu Glu 
    1415                 1420                 1425             


Gly Arg  Glu Pro Gly Ala Gly  Arg Trp Gly Pro Gly  Ser Ser Val 
    1430                 1435                 1440             


Gly Ser  Leu Gln Ala Leu Ser  Ser Ser Gln Arg Gly  Glu Phe Leu 
    1445                 1450                 1455             


Glu Ser  Asp Ser Val Ser Val  Ser Val Pro Trp Asp  Asp Ser Leu 
    1460                 1465                 1470             


Arg Gly  Ala Val Ala Gly Ala  Pro Lys Thr Ala Leu  Glu Thr Glu 
    1475                 1480                 1485             


Ser Gln  Asp Ser Ala Glu Pro  Ser Gly Ser Glu Glu  Glu Ser Asp 
    1490                 1495                 1500             


Pro Val  Ser Leu Glu Arg Glu  Asp Lys Val Pro Gly  Pro Leu Glu 
    1505                 1510                 1515             


Ile Pro  Ser Gly Met Glu Asp  Ala Gly Pro Gly Ala  Asp Ile Ile 
    1520                 1525                 1530             


Gly Val  Asn Gly Gln Gly Pro  Asn Leu Glu Gly Lys  Ser Gln His 
    1535                 1540                 1545             


Val Asn  Gly Gly Val Met Asn  Gly Leu Glu Gln Ser  Glu Glu Val 
    1550                 1555                 1560             


Gly Gln  Gly Met Pro Leu Val  Ser Glu Gly Asp Arg  Gly Ser Pro 
    1565                 1570                 1575             


Phe Gln  Glu Glu Glu Gly Ser  Ala Leu Lys Thr Ser  Trp Ala Gly 
    1580                 1585                 1590             


Ala Pro  Val His Leu Gly Gln  Gly Gln Phe Leu Lys  Phe Thr Gln 
    1595                 1600                 1605             


Arg Glu  Gly Asp Arg Glu Ser  Trp Ser Ser Gly Glu  Asp 
    1610                 1615                 1620     


